#ID = Affymetrix Probe Set ID #GB_ACC = GenBank Accession Number #SPOT_ID = identifies controls #Species Scientific Name = The genus and species of the organism represented by the probe set. #Annotation Date = The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site. #Sequence Type = #Sequence Source = The database from which the sequence used to design this probe set was taken. #Target Description = #Representative Public ID = The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used. #Gene Title = Title of Gene represented by the probe set. #Gene Symbol = A gene symbol, when one is available (from UniGene). #ENTREZ_GENE_ID = Entrez Gene Database UID #RefSeq Transcript ID = References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet. #Gene Ontology Biological Process = Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". #Gene Ontology Cellular Component = Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". #Gene Ontology Molecular Function = Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". ID GB_ACC SPOT_ID Species Scientific Name Annotation Date Sequence Type Sequence Source Target Description Representative Public ID Gene Title Gene Symbol ENTREZ_GENE_ID RefSeq Transcript ID Gene Ontology Biological Process Gene Ontology Cellular Component Gene Ontology Molecular Function 1007_s_at U48705 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database U48705 /FEATURE=mRNA /DEFINITION=HSU48705 Human receptor tyrosine kinase DDR gene, complete cds U48705 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 /// 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 1053_at M87338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank M87338 /FEATURE= /DEFINITION=HUMA1SBU Human replication factor C, 40-kDa subunit (A1) mRNA, complete cds M87338 replication factor C (activator 1) 2, 40kDa RFC2 5982 NM_001278791 /// NM_001278792 /// NM_001278793 /// NM_002914 /// NM_181471 /// XM_006716080 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 117_at X51757 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database X51757 /FEATURE=cds /DEFINITION=HSP70B Human heat-shock protein HSP70B' gene X51757 heat shock 70kDa protein 6 (HSP70B') HSPA6 3310 NM_002155 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0070370 // cellular heat acclimation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 121_at X69699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X69699 /FEATURE= /DEFINITION=HSPAX8A H.sapiens Pax8 mRNA X69699 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 1255_g_at L36861 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database L36861 /FEATURE=expanded_cds /DEFINITION=HUMGCAPB Homo sapiens guanylate cyclase activating protein (GCAP) gene exons 1-4, complete cds L36861 guanylate cyclase activator 1A (retina) GUCA1A 2978 NM_000409 /// XM_006715073 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1294_at L13852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank L13852 /FEATURE= /DEFINITION=HUME1URP Homo sapiens ubiquitin-activating enzyme E1 related protein mRNA, complete cds L13852 microRNA 5193 /// ubiquitin-like modifier activating enzyme 7 MIR5193 /// UBA7 7318 /// 100847079 NM_003335 /// NR_049825 /// XM_005265430 /// XM_006713321 0006464 // cellular protein modification process // inferred from direct assay /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // not recorded /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // not recorded /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay 1316_at X55005 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database X55005 /FEATURE=mRNA /DEFINITION=HSCERBAR Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene) X55005 thyroid hormone receptor, alpha THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 1320_at X79510 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database X79510 /FEATURE=cds /DEFINITION=HSPTPD1 H.sapiens mRNA for protein-tyrosine-phosphatase D1 X79510 protein tyrosine phosphatase, non-receptor type 21 PTPN21 11099 NM_007039 /// XM_005267287 /// XM_006720011 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 1405_i_at M21121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank M21121 /FEATURE= /DEFINITION=HUMTCSM Human T cell-specific protein (RANTES) mRNA, complete cds M21121 chemokine (C-C motif) ligand 5 CCL5 6352 NM_001278736 /// NM_002985 0000165 // MAPK cascade // inferred from mutant phenotype /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002676 // regulation of chronic inflammatory response // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // non-traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // traceable author statement /// 0010759 // positive regulation of macrophage chemotaxis // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031328 // positive regulation of cellular biosynthetic process // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045070 // positive regulation of viral genome replication // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045089 // positive regulation of innate immune response // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045948 // positive regulation of translational initiation // non-traceable author statement /// 0046427 // positive regulation of JAK-STAT cascade // traceable author statement /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from direct assay /// 0070234 // positive regulation of T cell apoptotic process // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 2000110 // negative regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000406 // positive regulation of T cell migration // inferred from direct assay /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // non-traceable author statement /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0030298 // receptor signaling protein tyrosine kinase activator activity // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031726 // CCR1 chemokine receptor binding // traceable author statement /// 0031729 // CCR4 chemokine receptor binding // traceable author statement /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0046817 // chemokine receptor antagonist activity // inferred from direct assay 1431_at J02843 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database J02843 /FEATURE=cds /DEFINITION=HUMCYPIIE Human cytochrome P450IIE1 (ethanol-inducible) gene, complete cds J02843 cytochrome P450, family 2, subfamily E, polypeptide 1 CYP2E1 1571 NM_000773 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0010193 // response to ozone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 1438_at X75208 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database X75208 /FEATURE=cds /DEFINITION=HSPTKR H.sapiens HEK2 mRNA for protein tyrosine kinase receptor X75208 EPH receptor B3 EPHB3 2049 NM_004443 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048546 // digestive tract morphogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 1487_at L38487 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database L38487 /FEATURE=mRNA /DEFINITION=HUMHERRA1 Human estrogen receptor-related protein (hERRa1) mRNA, 3' end, partial cds L38487 estrogen-related receptor alpha ESRRA 2101 NM_001282450 /// NM_001282451 /// NM_004451 /// XM_006718449 /// XM_006718450 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 1494_f_at M33318 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database M33318 /FEATURE=mRNA /DEFINITION=HUMCPIIA3A Human cytochrome P450IIA3 (CYP2A3) mRNA, complete cds M33318 cytochrome P450, family 2, subfamily A, polypeptide 6 CYP2A6 1548 NM_000762 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 1598_g_at L13720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank L13720 /FEATURE= /DEFINITION=HUMGAS Homo sapiens growth-arrest-specific protein (gas) mRNA, complete cds L13720 growth arrest-specific 6 GAS6 2621 NM_000820 /// NM_001143945 /// NM_001143946 0001764 // neuron migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010934 // macrophage cytokine production // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0019079 // viral genome replication // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035754 // B cell chemotaxis // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046718 // viral entry into host cell // inferred from direct assay /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050711 // negative regulation of interleukin-1 secretion // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070168 // negative regulation of biomineral tissue development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071307 // cellular response to vitamin K // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 0097241 // hematopoietic stem cell migration to bone marrow // inferred from direct assay /// 1900142 // negative regulation of oligodendrocyte apoptotic process // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from direct assay /// 2000533 // negative regulation of renal albumin absorption // inferred from sequence or structural similarity /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred from direct assay /// 0060090 // binding, bridging // inferred from direct assay 160020_at Z48481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Z48481 /FEATURE=cds /DEFINITION=HSMMPM1 H.sapiens mRNA for membrane-type matrix metalloproteinase 1 /NOTE=replacement of probe set 1301_s_at Z48481 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1729_at L41690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank L41690 /FEATURE= /DEFINITION=HUMTRADD Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds L41690 TNFRSF1A-associated via death domain TRADD 8717 NM_003789 /// NM_153425 /// XM_005256213 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction 1773_at L00635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank L00635 /FEATURE= /DEFINITION=HUMFPTB Human farnesyl-protein transferase beta-subunit mRNA, complete cds L00635 CHURC1-FNTB readthrough /// farnesyltransferase, CAAX box, beta CHURC1-FNTB /// FNTB 2342 /// 100529261 NM_001202558 /// NM_001202559 /// NM_002028 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018343 // protein farnesylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 177_at U38545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U38545 /FEATURE= /DEFINITION=HSU38545 Human ARF-activated phosphatidylcholine-specific phospholipase D1a (hPLD1) mRNA, complete cds U38545 phospholipase D1, phosphatidylcholine-specific PLD1 5337 NM_001130081 /// NM_002662 /// XM_005247533 /// XM_005247534 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 179_at U38980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U38980 /FEATURE= /DEFINITION=U38980 Human PMS2 related (hPMSR6) mRNA, complete cds U38980 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene DTX2P1-UPK3BP1-PMS2P11 441263 NR_023383 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 1861_at U66879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U66879 /FEATURE= /DEFINITION=HSU66879 Human Bcl-2 binding component 6 (bbc6) mRNA, complete cds U66879 BCL2-associated agonist of cell death BAD 572 NM_004322 /// NM_032989 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010918 // positive regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019050 // suppression by virus of host apoptotic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044342 // type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046031 // ADP metabolic process // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from sequence or structural similarity /// 0046902 // regulation of mitochondrial membrane permeability // inferred from mutant phenotype /// 0046931 // pore complex assembly // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060139 // positive regulation of apoptotic process by virus // inferred from electronic annotation /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071247 // cellular response to chromate // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071316 // cellular response to nicotine // inferred from direct assay /// 0071396 // cellular response to lipid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from electronic annotation /// 2000078 // positive regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from mutant phenotype /// 0008289 // lipid binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200000_s_at NM_006445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006445.1 /DEF=Homo sapiens U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p (PRP8), mRNA. /FEA=mRNA /GEN=PRP8 /PROD=U5 snRNP-specific protein (220 kD), ortholog ofS. cerevisiae Prp8p /DB_XREF=gi:5453983 /UG=Hs.181368 U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p /FL=gb:AB007510.1 gb:AF092565.1 gb:NM_006445.1 NM_006445 pre-mRNA processing factor 8 PRPF8 10594 NM_006445 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from electronic annotation /// 0030623 // U5 snRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200001_at NM_001749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001749.1 /DEF=Homo sapiens calpain 4, small subunit (30K) (CAPN4), mRNA. /FEA=mRNA /GEN=CAPN4 /PROD=calpain 4 small subunit /DB_XREF=gi:4502564 /UG=Hs.74451 calpain 4, small subunit (30K) /FL=gb:BC000592.1 gb:NM_001749.1 NM_001749 calpain, small subunit 1 CAPNS1 826 NM_001003962 /// NM_001749 /// XM_005259295 /// XM_005259296 /// XM_005259297 0006508 // proteolysis // not recorded /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200002_at NM_007209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007209.1 /DEF=Homo sapiens ribosomal protein L35 (RPL35), mRNA. /FEA=mRNA /GEN=RPL35 /PROD=ribosomal protein L35 /DB_XREF=gi:6005859 /UG=Hs.182825 ribosomal protein L35 /FL=gb:BC000348.1 gb:U12465.1 gb:NM_007209.1 NM_007209 ribosomal protein L35 RPL35 11224 NM_007209 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003729 // mRNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200003_s_at NM_000991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000991.1 /DEF=Homo sapiens ribosomal protein L28 (RPL28), mRNA. /FEA=mRNA /GEN=RPL28 /PROD=ribosomal protein L28 /DB_XREF=gi:4506626 /UG=Hs.4437 ribosomal protein L28 /FL=gb:BC000072.1 gb:NM_000991.1 gb:U14969.1 NM_000991 microRNA 6805 /// ribosomal protein L28 MIR6805 /// RPL28 6158 /// 102465483 NM_000991 /// NM_001136134 /// NM_001136135 /// NM_001136136 /// NM_001136137 /// NR_106863 /// XM_005259132 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200004_at NM_001418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001418.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), mRNA. /FEA=mRNA /GEN=EIF4G2 /PROD=eukaryotic translation initiation factor 4gamma, 2 /DB_XREF=gi:4503538 /UG=Hs.183684 eukaryotic translation initiation factor 4 gamma, 2 /FL=gb:U73824.1 gb:U76111.1 gb:NM_001418.1 NM_001418 eukaryotic translation initiation factor 4 gamma, 2 EIF4G2 1982 NM_001042559 /// NM_001172705 /// NM_001418 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0008219 // cell death // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200005_at NM_003753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003753.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) (EIF3S7), mRNA. /FEA=mRNA /GEN=EIF3S7 /PROD=eukaryotic translation initiation factor 3,subunit 7 (zeta, 6667kD) /DB_XREF=gi:4503522 /UG=Hs.55682 eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) /FL=gb:BC000328.1 gb:BC000469.1 gb:U54558.1 gb:NM_003753.1 NM_003753 eukaryotic translation initiation factor 3, subunit D EIF3D 8664 NM_003753 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200006_at NM_007262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007262.1 /DEF=Homo sapiens RNA-binding protein regulatory subunit (DJ-1), mRNA. /FEA=mRNA /GEN=DJ-1 /PROD=RNA-binding protein regulatory subunit /DB_XREF=gi:6005748 /UG=Hs.10958 RNA-binding protein regulatory subunit /FL=gb:AF021819.1 gb:NM_007262.1 gb:D61380.1 NM_007262 parkinson protein 7 PARK7 11315 NM_001123377 /// NM_007262 /// XM_005263424 0001933 // negative regulation of protein phosphorylation // inferred from genetic interaction /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from genetic interaction /// 0006508 // proteolysis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007338 // single fertilization // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from genetic interaction /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045560 // regulation of TRAIL receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046826 // negative regulation of protein export from nucleus // inferred from genetic interaction /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051583 // dopamine uptake involved in synaptic transmission // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay /// 1900182 // positive regulation of protein localization to nucleus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1901671 // positive regulation of superoxide dismutase activity // inferred from direct assay /// 1901984 // negative regulation of protein acetylation // inferred from direct assay /// 1903073 // negative regulation of death-inducing signaling complex assembly // inferred by curator /// 1903094 // negative regulation of protein K48-linked deubiquitination // inferred from direct assay /// 1903122 // negative regulation of TRAIL-activated apoptotic signaling pathway // inferred from mutant phenotype /// 2000157 // negative regulation of ubiquitin-specific protease activity // inferred from direct assay /// 2000277 // positive regulation of oxidative phosphorylation uncoupler activity // inferred from electronic annotation /// 2000825 // positive regulation of androgen receptor activity // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004601 // peroxidase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0016532 // superoxide dismutase copper chaperone activity // inferred from direct assay /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044388 // small protein activating enzyme binding // inferred from physical interaction /// 0044390 // small protein conjugating enzyme binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051920 // peroxiredoxin activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction /// 1903135 // cupric ion binding // inferred from direct assay /// 1903136 // cuprous ion binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 200007_at NM_003134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003134.1 /DEF=Homo sapiens signal recognition particle 14kD (homologous Alu RNA-binding protein) (SRP14), mRNA. /FEA=mRNA /GEN=SRP14 /PROD=signal recognition particle 14kD (homologous AluRNA-binding protein) /DB_XREF=gi:4507210 /UG=Hs.180394 signal recognition particle 14kD (homologous Alu RNA-binding protein) /FL=gb:NM_003134.1 gb:U07857.1 NM_003134 signal recognition particle 14kDa (homologous Alu RNA binding protein) SRP14 6727 NM_003134 /// NR_104021 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0048500 // signal recognition particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0030942 // endoplasmic reticulum signal peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200008_s_at D13988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13988.1 /DEF=Human rab GDI mRNA, complete cds. /FEA=mRNA /PROD=human rab GDI /DB_XREF=gi:285974 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2 D13988 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200009_at NM_001494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001494.2 /DEF=Homo sapiens GDP dissociation inhibitor 2 (GDI2), mRNA. /FEA=mRNA /GEN=GDI2 /PROD=GDP dissociation inhibitor 2 /DB_XREF=gi:6598322 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2 NM_001494 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200010_at NM_000975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000975.1 /DEF=Homo sapiens ribosomal protein L11 (RPL11), mRNA. /FEA=mRNA /GEN=RPL11 /PROD=ribosomal protein L11 /DB_XREF=gi:4506594 /UG=Hs.179943 ribosomal protein L11 /FL=gb:L05092.1 gb:NM_000975.1 NM_000975 ribosomal protein L11 RPL11 6135 NM_000975 /// NM_001199802 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200011_s_at NM_001659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001659.1 /DEF=Homo sapiens ADP-ribosylation factor 3 (ARF3), mRNA. /FEA=mRNA /GEN=ARF3 /PROD=ADP-ribosylation factor 3 /DB_XREF=gi:4502202 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1 NM_001659 ADP-ribosylation factor 3 ARF3 377 NM_001659 /// XM_005268856 /// XM_006719391 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 200012_x_at NM_000982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000982.1 /DEF=Homo sapiens ribosomal protein L21 (gene or pseudogene) (RPL21), mRNA. /FEA=mRNA /GEN=RPL21 /PROD=ribosomal protein L21 (gene or pseudogene) /DB_XREF=gi:4506610 /UG=Hs.184108 ribosomal protein L21 /FL=gb:BC001603.1 gb:NM_000982.1 gb:U14967.1 gb:U25789.1 NM_000982 ribosomal protein L21 /// ribosomal protein L21 pseudogene 28 /// small nucleolar RNA, H/ACA box 27 /// small nucleolar RNA, C/D box 102 RPL21 /// RPL21P28 /// SNORA27 /// SNORD102 6144 /// 26771 /// 619499 /// 100131205 NM_000982 /// NR_002574 /// NR_002575 /// NR_026911 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200013_at NM_000986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000986.1 /DEF=Homo sapiens ribosomal protein L24 (RPL24), mRNA. /FEA=mRNA /GEN=RPL24 /PROD=ribosomal protein L24 /DB_XREF=gi:4506618 /UG=Hs.184582 ribosomal protein L24 /FL=gb:BC000690.1 gb:M94314.1 gb:NM_000986.1 NM_000986 ribosomal protein L24 RPL24 6152 NM_000986 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200014_s_at NM_004500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004500.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1C2) (HNRPC), mRNA. /FEA=mRNA /GEN=HNRPC /PROD=heterogeneous nuclear ribonucleoprotein C(C1C2) /DB_XREF=gi:4758543 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1 NM_004500 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200015_s_at NM_004404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004404.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 5 (NEDD5), mRNA. /FEA=mRNA /GEN=NEDD5 /PROD=neural precursor cell expressed, developmentallydown-regulated 5 /DB_XREF=gi:4758157 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1 NM_004404 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_001282972 /// NM_001282973 /// NM_004404 /// NM_006155 /// XM_005247011 /// XM_005247012 /// XM_005247013 /// XM_006712546 /// XM_006712547 /// XM_006712548 /// XM_006712549 /// XM_006712550 0002036 // regulation of L-glutamate transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation 200016_x_at NM_002136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002136.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A1 (HNRPA1), mRNA. /FEA=mRNA /GEN=HNRPA1 /PROD=heterogeneous nuclear ribonucleoprotein A1 /DB_XREF=gi:4504444 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 /FL=gb:NM_002136.1 NM_002136 heterogeneous nuclear ribonucleoprotein A1 /// heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 HNRNPA1 /// HNRNPA1P10 3178 /// 664709 NM_002136 /// NM_031157 /// NR_002944 /// XM_005268826 /// XR_245923 /// XR_245924 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200017_at NM_002954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002954.1 /DEF=Homo sapiens ribosomal protein S27a (RPS27A), mRNA. /FEA=mRNA /GEN=RPS27A /PROD=ribosomal protein S27a /DB_XREF=gi:4506712 /UG=Hs.3297 ribosomal protein S27a /FL=gb:BC001392.1 gb:BC005328.1 gb:NM_002954.1 NM_002954 ribosomal protein S27a RPS27A 6233 NM_001135592 /// NM_001177413 /// NM_002954 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200018_at NM_001017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001017.1 /DEF=Homo sapiens ribosomal protein S13 (RPS13), mRNA. /FEA=mRNA /GEN=RPS13 /PROD=ribosomal protein S13 /DB_XREF=gi:4506684 /UG=Hs.165590 ribosomal protein S13 /FL=gb:BC000475.1 gb:L01124.1 gb:NM_001017.1 NM_001017 uncharacterized LOC100508408 /// ribosomal protein S13 /// small nucleolar RNA, C/D box 14B LOC100508408 /// RPS13 /// SNORD14B 6207 /// 85388 /// 100508408 NM_001017 /// NR_001452 /// XR_111163 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200019_s_at NM_001997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001997.1 /DEF=Homo sapiens Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 (FAU), mRNA. /FEA=mRNA /GEN=FAU /PROD=Finkel-Biskis-Reilly murine sarcoma virus(FBR-MuSV) ubiquitously expressed (fox derived); ribosomalprotein S30 /DB_XREF=gi:4503658 /UG=Hs.177415 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 /FL=gb:NM_001997.1 NM_001997 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed FAU 2197 NM_001997 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200020_at NM_007375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007375.1 /DEF=Homo sapiens TAR DNA binding protein (TARDBP), mRNA. /FEA=mRNA /GEN=TARDBP /PROD=TAR DNA binding protein /DB_XREF=gi:6678270 /UG=Hs.193989 TAR DNA binding protein /FL=gb:AL050265.1 gb:NM_007375.1 gb:U23731.1 NM_007375 TAR DNA binding protein TARDBP 23435 NM_007375 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200021_at NM_005507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005507.1 /DEF=Homo sapiens cofilin 1 (non-muscle) (CFL1), mRNA. /FEA=mRNA /GEN=CFL1 /PROD=cofilin 1 (non-muscle) /DB_XREF=gi:5031634 /UG=Hs.180370 cofilin 1 (non-muscle) /FL=gb:NM_005507.1 NM_005507 cofilin 1 (non-muscle) CFL1 1072 NM_005507 0000910 // cytokinesis // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045792 // negative regulation of cell size // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200022_at NM_000979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000979.1 /DEF=Homo sapiens ribosomal protein L18 (RPL18), mRNA. /FEA=mRNA /GEN=RPL18 /PROD=ribosomal protein L18 /DB_XREF=gi:4506606 /UG=Hs.75458 ribosomal protein L18 /FL=gb:BC000374.1 gb:L11566.1 gb:NM_000979.1 NM_000979 ribosomal protein L18 RPL18 6141 NM_000979 /// NM_001270490 /// NR_073022 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200023_s_at NM_003754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003754.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) (EIF3S5), mRNA. /FEA=mRNA /GEN=EIF3S5 /PROD=eukaryotic translation initiation factor 3,subunit 5 (epsilon, 47kD) /DB_XREF=gi:4503518 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1 NM_003754 eukaryotic translation initiation factor 3, subunit F EIF3F 8665 NM_003754 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200024_at NM_001009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001009.1 /DEF=Homo sapiens ribosomal protein S5 (RPS5), mRNA. /FEA=mRNA /GEN=RPS5 /PROD=ribosomal protein S5 /DB_XREF=gi:4506728 /UG=Hs.76194 ribosomal protein S5 /FL=gb:NM_001009.1 gb:U14970.1 NM_001009 ribosomal protein S5 RPS5 6193 NM_001009 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from genetic interaction /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006450 // regulation of translational fidelity // inferred from genetic interaction /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200025_s_at NM_000988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000988.1 /DEF=Homo sapiens ribosomal protein L27 (RPL27), mRNA. /FEA=mRNA /GEN=RPL27 /PROD=ribosomal protein L27 /DB_XREF=gi:4506622 /UG=Hs.111611 ribosomal protein L27 /FL=gb:BC002588.1 gb:L05094.1 gb:L19527.1 gb:NM_000988.1 NM_000988 ribosomal protein L27 RPL27 6155 NM_000988 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200026_at NM_000995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000995.1 /DEF=Homo sapiens ribosomal protein L34 (RPL34), mRNA. /FEA=mRNA /GEN=RPL34 /PROD=ribosomal protein L34 /DB_XREF=gi:4506636 /UG=Hs.250895 ribosomal protein L34 /FL=gb:L38941.1 gb:BC001773.1 gb:NM_000995.1 NM_000995 ribosomal protein L34 RPL34 6164 NM_000995 /// NM_033625 /// XM_005263172 /// XM_006714287 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200027_at NM_004539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004539.2 /DEF=Homo sapiens asparaginyl-tRNA synthetase (NARS), mRNA. /FEA=mRNA /GEN=NARS /PROD=asparaginyl-tRNA synthetase /DB_XREF=gi:7262387 /UG=Hs.181311 asparaginyl-tRNA synthetase /FL=gb:BC001687.1 gb:D84273.1 gb:NM_004539.2 NM_004539 asparaginyl-tRNA synthetase NARS 4677 NM_004539 /// XM_005266700 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006421 // asparaginyl-tRNA aminoacylation // inferred from electronic annotation /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0004816 // asparagine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200028_s_at NM_020151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020151.1 /DEF=Homo sapiens GTT1 protein (GTT1), mRNA. /FEA=mRNA /GEN=GTT1 /PROD=GTT1 protein /DB_XREF=gi:9910251 /UG=Hs.283722 GTT1 protein /FL=gb:AF270647.1 gb:NM_020151.1 NM_020151 StAR-related lipid transfer (START) domain containing 7 STARD7 56910 NM_020151 /// NM_139267 0005739 // mitochondrion // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation 200029_at NM_000981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000981.1 /DEF=Homo sapiens ribosomal protein L19 (RPL19), mRNA. /FEA=mRNA /GEN=RPL19 /PROD=ribosomal protein L19 /DB_XREF=gi:4506608 /UG=Hs.252723 ribosomal protein L19 /FL=gb:BC000530.1 gb:NM_000981.1 NM_000981 ribosomal protein L19 RPL19 6143 NM_000981 /// XM_005257564 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200030_s_at NM_002635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002635.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 (SLC25A3), nuclear gene encoding mitochondrial protein, transcript variant 1b, mRNA. /FEA=mRNA /GEN=SLC25A3 /PROD=phosphate carrier precursor isoform 1b /DB_XREF=gi:4505774 /UG=Hs.78713 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 /FL=gb:BC000998.1 gb:BC001328.1 gb:BC003504.1 gb:BC004345.1 gb:NM_002635.1 NM_002635 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 SLC25A3 5250 NM_002635 /// NM_005888 /// NM_213611 /// NM_213612 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006810 // transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015293 // symporter activity // inferred from electronic annotation /// 0015320 // phosphate ion carrier activity // traceable author statement /// 0032403 // protein complex binding // inferred from direct assay 200031_s_at NM_001015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001015.1 /DEF=Homo sapiens ribosomal protein S11 (RPS11), mRNA. /FEA=mRNA /GEN=RPS11 /PROD=ribosomal protein S11 /DB_XREF=gi:4506680 /UG=Hs.182740 ribosomal protein S11 /FL=gb:NM_001015.1 NM_001015 ribosomal protein S11 /// small nucleolar RNA, C/D box 35B RPS11 /// SNORD35B 6205 /// 84546 NM_001015 /// NR_001285 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200032_s_at NM_000661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000661.1 /DEF=Homo sapiens ribosomal protein L9 (RPL9), mRNA. /FEA=mRNA /GEN=RPL9 /PROD=ribosomal protein L9 /DB_XREF=gi:4506664 /UG=Hs.157850 ribosomal protein L9 /FL=gb:U09953.1 gb:NM_000661.1 NM_000661 ribosomal protein L9 RPL9 6133 NM_000661 /// NM_001024921 /// XM_005262661 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0047961 // glycine N-acyltransferase activity // inferred from electronic annotation 200033_at NM_004396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004396.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) (DDX5), mRNA. /FEA=mRNA /GEN=DDX5 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 /DB_XREF=gi:13514826 /UG=Hs.76053 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) /FL=gb:NM_004396.2 NM_004396 DEAD (Asp-Glu-Ala-Asp) box helicase 5 /// microRNA 3064 /// microRNA 5047 DDX5 /// MIR3064 /// MIR5047 1655 /// 100616387 /// 100616408 NM_004396 /// NR_039891 /// NR_039969 /// XM_005257111 /// XM_006721738 /// XR_429871 /// XR_429872 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // inferred from mutant phenotype /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay 200034_s_at NM_000970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000970.1 /DEF=Homo sapiens ribosomal protein L6 (RPL6), mRNA. /FEA=mRNA /GEN=RPL6 /PROD=ribosomal protein L6 /DB_XREF=gi:4506656 /UG=Hs.174131 ribosomal protein L6 /FL=gb:BC004138.1 gb:D17554.1 gb:NM_000970.1 gb:AF261087.1 NM_000970 ribosomal protein L6 RPL6 6128 NM_000970 /// NM_001024662 /// XM_005253920 /// XM_006719546 /// XM_006719547 /// XM_006719548 /// XM_006719549 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200035_at NM_015343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015343.1 /DEF=Homo sapiens hypothetical protein (HSA011916), mRNA. /FEA=mRNA /GEN=HSA011916 /PROD=hypothetical protein /DB_XREF=gi:7661721 /UG=Hs.84359 hypothetical protein /FL=gb:NM_015343.1 NM_015343 CTD nuclear envelope phosphatase 1 CTDNEP1 23399 NM_001143775 /// NM_015343 0006470 // protein dephosphorylation // inferred from direct assay /// 0006998 // nuclear envelope organization // inferred from direct assay /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from genetic interaction /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0071595 // Nem1-Spo7 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200036_s_at NM_007104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007104.2 /DEF=Homo sapiens ribosomal protein L10a (RPL10A), mRNA. /FEA=mRNA /GEN=RPL10A /PROD=ribosomal protein L10a /DB_XREF=gi:6325471 /UG=Hs.252574 ribosomal protein L10a /FL=gb:U12404.1 gb:NM_007104.2 NM_007104 ribosomal protein L10a RPL10A 4736 NM_007104 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200037_s_at NM_016587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016587.1 /DEF=Homo sapiens heterochromatin-like protein 1 (HECH), mRNA. /FEA=mRNA /GEN=HECH /PROD=heterochromatin-like protein 1 /DB_XREF=gi:7705406 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1 NM_016587 chromobox homolog 3 CBX3 11335 NM_007276 /// NM_016587 /// XM_005249611 /// XM_005249612 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation 0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 1990226 // histone methyltransferase binding // inferred from physical interaction 200038_s_at NM_000985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000985.1 /DEF=Homo sapiens ribosomal protein L17 (RPL17), mRNA. /FEA=mRNA /GEN=RPL17 /PROD=ribosomal protein L17 /DB_XREF=gi:4506616 /UG=Hs.82202 ribosomal protein L17 /FL=gb:BC000502.1 gb:NM_000985.1 NM_000985 chromosome 18 open reading frame 32 /// ribosomal protein L17 /// RPL17-C18orf32 readthrough /// small nucleolar RNA, C/D box 58A /// small nucleolar RNA, C/D box 58B /// small nucleolar RNA, C/D box 58C C18orf32 /// RPL17 /// RPL17-C18orf32 /// SNORD58A /// SNORD58B /// SNORD58C 6139 /// 26790 /// 26791 /// 497661 /// 100124516 /// 100526842 NM_000985 /// NM_001035005 /// NM_001035006 /// NM_001199340 /// NM_001199341 /// NM_001199342 /// NM_001199343 /// NM_001199344 /// NM_001199345 /// NM_001199346 /// NM_001199355 /// NM_001199356 /// NR_002571 /// NR_002572 /// NR_003701 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 200039_s_at NM_002794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002794.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 2 (PSMB2), mRNA. /FEA=mRNA /GEN=PSMB2 /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:4506194 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1 NM_002794 proteasome (prosome, macropain) subunit, beta type, 2 PSMB2 5690 NM_001199779 /// NM_001199780 /// NM_002794 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200040_at NM_006559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006559.1 /DEF=Homo sapiens GAP-associated tyrosine phosphoprotein p62 (Sam68) (SAM68), mRNA. /FEA=mRNA /GEN=SAM68 /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:5730026 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1 NM_006559 KH domain containing, RNA binding, signal transduction associated 1 KHDRBS1 10657 NM_001271878 /// NM_006559 /// NR_073498 /// NR_073499 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0031647 // regulation of protein stability // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045948 // positive regulation of translational initiation // inferred from direct assay /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070618 // Grb2-Sos complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200041_s_at NM_004640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004640.1 /DEF=Homo sapiens HLA-B associated transcript-1 (D6S81E), mRNA. /FEA=mRNA /GEN=D6S81E /PROD=HLA-B associated transcript-1 /DB_XREF=gi:4758111 /UG=Hs.55296 HLA-B associated transcript-1 /FL=gb:BC004350.1 gb:NM_004640.1 NM_004640 ATP6V1G2-DDX39B readthrough (NMD candidate) /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B /// small nucleolar RNA, C/D box 84 ATP6V1G2-DDX39B /// DDX39B /// SNORD84 7919 /// 692199 /// 100532737 NM_004640 /// NM_080598 /// NR_003065 /// NR_037852 /// NR_037853 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005688 // U6 snRNP // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0030621 // U4 snRNA binding // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200042_at NM_014306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014306.1 /DEF=Homo sapiens hypothetical protein (HSPC117), mRNA. /FEA=mRNA /GEN=HSPC117 /PROD=similar to C. elegens hypothetical 55.2 kDprotein F16A11.2 /DB_XREF=gi:7657014 /UG=Hs.10729 hypothetical protein /FL=gb:BC000151.1 gb:BC002970.1 gb:AF161466.1 gb:NM_014306.1 gb:AF155658.1 NM_014306 RNA 2',3'-cyclic phosphate and 5'-OH ligase RTCB 51493 NM_014306 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from direct assay /// 0006396 // RNA processing // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0072669 // tRNA-splicing ligase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003972 // RNA ligase (ATP) activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008452 // RNA ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200043_at NM_004450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004450.1 /DEF=Homo sapiens enhancer of rudimentary (Drosophila) homolog (ERH), mRNA. /FEA=mRNA /GEN=ERH /PROD=enhancer of rudimentary (Drosophila) homolog /DB_XREF=gi:4758301 /UG=Hs.118757 enhancer of rudimentary (Drosophila) homolog /FL=gb:D85758.1 gb:U66871.1 gb:NM_004450.1 NM_004450 enhancer of rudimentary homolog (Drosophila) ERH 2079 NM_004450 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0030496 // midbody // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 200044_at NM_003769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1 NM_003769 glutamyl-tRNA(Gln) amidotransferase, subunit C /// serine/arginine-rich splicing factor 9 GATC /// SRSF9 8683 /// 283459 NM_003769 /// NM_176818 /// NR_033684 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 200045_at NM_001090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001090.1 /DEF=Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 1 (ABCF1), mRNA. /FEA=mRNA /GEN=ABCF1 /PROD=ATP-binding cassette, sub-family F, member 1 /DB_XREF=gi:10947134 /UG=Hs.9573 ATP-binding cassette, sub-family F (GCN20), member 1 /FL=gb:NM_001090.1 gb:AF027302.1 NM_001090 ATP-binding cassette, sub-family F (GCN20), member 1 ABCF1 23 NM_001025091 /// NM_001090 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from mutant phenotype /// 0006954 // inflammatory response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0008494 // translation activator activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200046_at NM_001344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001344.1 /DEF=Homo sapiens defender against cell death 1 (DAD1), mRNA. /FEA=mRNA /GEN=DAD1 /PROD=defender against cell death 1 /DB_XREF=gi:4503252 /UG=Hs.82890 defender against cell death 1 /FL=gb:NM_001344.1 gb:D15057.1 NM_001344 defender against cell death 1 DAD1 1603 NM_001344 0001824 // blastocyst development // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred by curator /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004576 // oligosaccharyl transferase activity // inferred from sequence or structural similarity /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred by curator /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 200047_s_at NM_003403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003403.2 /DEF=Homo sapiens YY1 transcription factor (YY1), mRNA. /FEA=mRNA /GEN=YY1 /PROD=YY1 transcription factor /DB_XREF=gi:6042207 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 NM_003403 YY1 transcription factor YY1 7528 NM_003403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200048_s_at NM_006694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006694.1 /DEF=Homo sapiens jumping translocation breakpoint (JTB), mRNA. /FEA=mRNA /GEN=JTB /PROD=jumping translocation breakpoint /DB_XREF=gi:5729888 /UG=Hs.6396 jumping translocation breakpoint /FL=gb:BC000499.1 gb:BC001363.1 gb:BC000996.2 gb:BC001667.1 gb:AB016488.1 gb:AF131797.1 gb:NM_006694.1 gb:AF115850.2 NM_006694 jumping translocation breakpoint JTB 10899 NM_006694 0000910 // cytokinesis // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0019901 // protein kinase binding // inferred from direct assay 200049_at NM_007067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007067.1 /DEF=Homo sapiens histone acetyltransferase (HBOA), mRNA. /FEA=mRNA /GEN=HBOA /PROD=histone acetyltransferase /DB_XREF=gi:5901961 /UG=Hs.21907 histone acetyltransferase /FL=gb:AF074606.1 gb:AF140360.1 gb:NM_007067.1 NM_007067 K(lysine) acetyltransferase 7 KAT7 11143 NM_001199155 /// NM_001199156 /// NM_001199157 /// NM_001199158 /// NM_007067 0006260 // DNA replication // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200050_at NM_007145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007145.1 /DEF=Homo sapiens zinc finger protein 146 (ZNF146), mRNA. /FEA=mRNA /GEN=ZNF146 /PROD=zinc finger protein 146 /DB_XREF=gi:6005965 /UG=Hs.301819 zinc finger protein 146 /FL=gb:BC005154.1 gb:NM_007145.1 NM_007145 zinc finger protein 146 ZNF146 7705 NM_001099638 /// NM_001099639 /// NM_007145 /// XM_005259214 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0008201 // heparin binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200051_at NM_005146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005146.1 /DEF=Homo sapiens squamous cell carcinoma antigen recognised by T cells (SART1), mRNA. /FEA=mRNA /GEN=SART1 /PROD=squamous cell carcinoma antigen recognised by Tcells /DB_XREF=gi:10863888 /UG=Hs.288319 squamous cell carcinoma antigen recognised by T cells /FL=gb:NM_005146.1 gb:BC001058.1 gb:AB006198.1 NM_005146 squamous cell carcinoma antigen recognized by T cells SART1 9092 NM_005146 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045585 // positive regulation of cytotoxic T cell differentiation // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200052_s_at NM_004515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004515.1 /DEF=Homo sapiens interleukin enhancer binding factor 2, 45kD (ILF2), mRNA. /FEA=mRNA /GEN=ILF2 /PROD=interleukin enhancer binding factor 2, 45kD /DB_XREF=gi:4758601 /UG=Hs.75117 interleukin enhancer binding factor 2, 45kD /FL=gb:BC000382.1 gb:NM_004515.1 gb:U10323.1 NM_004515 interleukin enhancer binding factor 2 ILF2 3608 NM_001267809 /// NM_004515 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200053_at NM_004890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004890.1 /DEF=Homo sapiens sperm associated antigen 7 (SPAG7), mRNA. /FEA=mRNA /GEN=SPAG7 /PROD=sperm associated antigen 7 /DB_XREF=gi:4757715 /UG=Hs.90436 sperm associated antigen 7 /FL=gb:AF047437.1 gb:NM_004890.1 NM_004890 sperm associated antigen 7 SPAG7 9552 NM_004890 /// XM_005256865 /// XM_006721600 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 200054_at NM_003904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003904.1 /DEF=Homo sapiens zinc finger protein 259 (ZNF259), mRNA. /FEA=mRNA /GEN=ZNF259 /PROD=zinc finger protein 259 /DB_XREF=gi:4508020 /UG=Hs.7165 zinc finger protein 259 /FL=gb:BC004256.1 gb:AF019767.1 gb:NM_003904.1 NM_003904 ZPR1 zinc finger ZPR1 8882 NM_003904 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001834 // trophectodermal cell proliferation // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030576 // Cajal body organization // inferred from mutant phenotype /// 0030576 // Cajal body organization // inferred from sequence or structural similarity /// 0031641 // regulation of myelination // inferred from sequence or structural similarity /// 0033120 // positive regulation of RNA splicing // inferred from mutant phenotype /// 0042023 // DNA endoreduplication // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0061564 // axon development // inferred from mutant phenotype /// 0061564 // axon development // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 1902742 // apoptotic process involved in development // inferred from sequence or structural similarity /// 1990261 // pre-mRNA catabolic process // inferred from mutant phenotype /// 2000672 // negative regulation of motor neuron apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032797 // SMN complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031369 // translation initiation factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200055_at NM_006284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006284.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD (TAF2H), mRNA. /FEA=mRNA /GEN=TAF2H /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, H, 30kD /DB_XREF=gi:5454105 /UG=Hs.89657 TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD /FL=gb:NM_006284.1 gb:U13991.1 NM_006284 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa TAF10 6881 NM_006284 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 200056_s_at NM_006333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006333.1 /DEF=Homo sapiens nuclear DNA-binding protein (C1D), mRNA. /FEA=mRNA /GEN=C1D /PROD=nuclear DNA-binding protein /DB_XREF=gi:5453582 /UG=Hs.15164 nuclear DNA-binding protein /FL=gb:NM_006333.1 NM_006333 C1D nuclear receptor corepressor C1D 10438 NM_001190263 /// NM_001190265 /// NM_006333 /// NM_173177 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0000176 // nuclear exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation 200057_s_at NM_007363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007363.2 /DEF=Homo sapiens non-POU-domain-containing, octamer-binding (NONO), mRNA. /FEA=mRNA /GEN=NONO /PROD=non-Pou domain-containing octamer (ATGCAAAT)binding protein /DB_XREF=gi:7657382 /UG=Hs.172207 non-POU-domain-containing, octamer-binding /FL=gb:NM_007363.2 NM_007363 non-POU domain containing, octamer-binding NONO 4841 NM_001145408 /// NM_001145409 /// NM_001145410 /// NM_007363 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200058_s_at BC001417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001417.1 /DEF=Homo sapiens, Similar to U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family), clone MGC:2580, mRNA, complete cds. /FEA=mRNA /PROD=Similar to U5 snRNP-specific protein, 200 kDa(DEXH RNA helicase family) /DB_XREF=gi:12655128 /UG=Hs.246112 KIAA0788 protein /FL=gb:BC001417.1 gb:AF119874.1 BC001417 U5 small nuclear ribonucleoprotein 200 kDa helicase-like /// small nuclear ribonucleoprotein 200kDa (U5) LOC101929240 /// SNRNP200 23020 /// 101929240 NM_014014 /// XR_243770 /// XR_253745 /// XR_424859 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200059_s_at BC001360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001360.1 /DEF=Homo sapiens, ras homolog gene family, member A, clone MGC:2330, mRNA, complete cds. /FEA=mRNA /PROD=ras homolog gene family, member A /DB_XREF=gi:12655024 /UG=Hs.77273 ras homolog gene family, member A /FL=gb:NM_001664.1 gb:BC001360.1 gb:L25080.1 BC001360 ras homolog family member A RHOA 387 NM_001664 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008064 // regulation of actin polymerization or depolymerization // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031098 // stress-activated protein kinase signaling cascade // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0033688 // regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0036089 // cleavage furrow formation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0061383 // trabecula morphogenesis // inferred from sequence or structural similarity /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200060_s_at BC001659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001659.1 /DEF=Homo sapiens, RNA-binding protein S1, serine-rich domain, clone MGC:1125, mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein S1, serine-rich domain /DB_XREF=gi:12804496 /UG=Hs.75104 RNA-binding protein S1, serine-rich domain /FL=gb:BC001659.1 gb:BC001838.1 BC001659 RNA binding protein S1, serine-rich domain RNPS1 10921 NM_001286625 /// NM_001286626 /// NM_001286627 /// NM_006711 /// NM_080594 /// NR_104485 /// XM_005255048 /// XM_005255049 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // traceable author statement /// 0061574 // ASAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // non-traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200061_s_at BC000523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000523.1 /DEF=Homo sapiens, Similar to ribosomal protein S24, clone MGC:8595, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein S24 /DB_XREF=gi:12653502 /UG=Hs.180450 ribosomal protein S24 /FL=gb:BC000523.1 gb:BC003149.1 BC000523 ribosomal protein S24 RPS24 6229 NM_001026 /// NM_001142282 /// NM_001142283 /// NM_001142284 /// NM_001142285 /// NM_033022 /// XM_006717938 /// XR_428711 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200062_s_at L05095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L05095.1 /DEF=Homo sapiens ribosomal protein L30 mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L30 /DB_XREF=gi:388034 /UG=Hs.111222 ribosomal protein L30 /FL=gb:L05095.1 gb:NM_000989.1 L05095 ribosomal protein L30 RPL30 6156 NM_000989 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200063_s_at BC002398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002398.1 /DEF=Homo sapiens, nucleophosmin (nucleolar phosphoprotein B23, numatrin), clone MGC:8463, mRNA, complete cds. /FEA=mRNA /PROD=nucleophosmin (nucleolar phosphoprotein B23,numatrin) /DB_XREF=gi:12803184 /UG=Hs.9614 nucleophosmin (nucleolar phosphoprotein B23, numatrin) /FL=gb:NM_002520.1 gb:BC002398.1 gb:BC003670.1 gb:M23613.1 gb:M26697.1 gb:M28699.1 BC002398 nucleophosmin (nucleolar phosphoprotein B23, numatrin) NPM1 4869 NM_001037738 /// NM_002520 /// NM_199185 /// XM_005265920 /// XM_006714869 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 200064_at AF275719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF275719.1 /DEF=Homo sapiens isolate Liv chaperone protein HSP90 beta (HSP90BETA) mRNA, complete cds. /FEA=mRNA /GEN=HSP90BETA /PROD=chaperone protein HSP90 beta /DB_XREF=gi:9082288 /UG=Hs.74335 heat shock 90kD protein 1, beta /FL=gb:BC004928.1 gb:M16660.1 gb:NM_007355.1 gb:AF275719.1 AF275719 heat shock protein 90kDa alpha (cytosolic), class B member 1 HSP90AB1 3326 NM_001271969 /// NM_001271970 /// NM_001271971 /// NM_001271972 /// NM_007355 /// NR_073528 /// XM_005249075 0001890 // placenta development // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009651 // response to salt stress // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // inferred from mutant phenotype /// 0060338 // regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from sequence or structural similarity /// 0030911 // TPR domain binding // inferred from sequence or structural similarity /// 0032564 // dATP binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200065_s_at AF052179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF052179.1 /DEF=Homo sapiens clone 24537 ADP-ribosylation factor 1 mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor 1 /DB_XREF=gi:3360490 /UG=Hs.74571 ADP-ribosylation factor 1 /FL=gb:M84326.1 gb:M36340.1 gb:AF055002.1 gb:AF052179.1 gb:NM_001658.2 AF052179 ADP-ribosylation factor 1 /// microRNA 3620 ARF1 /// MIR3620 375 /// 100500810 NM_001024226 /// NM_001024227 /// NM_001024228 /// NM_001658 /// NR_037415 0002090 // regulation of receptor internalization // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0034315 // regulation of Arp2/3 complex-mediated actin nucleation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0097061 // dendritic spine organization // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200066_at AF182645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182645.1 /DEF=Homo sapiens chondrosarcoma-associated protein 2 (CSA2) mRNA, complete cds. /FEA=mRNA /GEN=CSA2 /PROD=chondrosarcoma-associated protein 2 /DB_XREF=gi:5901877 /UG=Hs.8024 IK cytokine, down-regulator of HLA II /FL=gb:NM_006083.2 gb:AF182645.1 AF182645 IK cytokine, down-regulator of HLA II IK 3550 NM_006083 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 200067_x_at AL078596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078596 /DEF=Human DNA sequence from clone RP3-429G5 on chromosome 6q21-22.1. Contains the NR2E1 gene for nuclear receptor 2E1 (tailless, TLL, TLX, XTLL), the 3 end of the SNX3 gene for sorting nexin 3, ESTs, STSs, GSSs and four predicted CpG islands /FEA=mRNA_2 /DB_XREF=gi:6010168 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1 AL078596 sorting nexin 3 SNX3 8724 NM_003795 /// NM_152827 /// NM_152828 /// XM_005267192 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 200068_s_at M94859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M94859.1 /DEF=Human calnexin mRNA, complete cds. /FEA=mRNA /PROD=calnexin /DB_XREF=gi:179831 /UG=Hs.155560 calnexin /FL=gb:NM_001746.1 gb:BC003552.1 gb:M94859.1 gb:M98452.1 gb:L10284.1 gb:L18887.1 M94859 calnexin CANX 821 NM_001024649 /// NM_001746 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0072583 // clathrin-mediated endocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200069_at AI656011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI656011 /FEA=EST /DB_XREF=gi:4739990 /DB_XREF=est:tt42e08.x1 /CLONE=IMAGE:2243462 /UG=Hs.116875 KIAA0156 gene product /FL=gb:AB020880.1 gb:NM_014706.1 gb:D63879.1 AI656011 squamous cell carcinoma antigen recognized by T cells 3 SART3 9733 NM_014706 /// XM_005269241 0006396 // RNA processing // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200070_at BC001393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001393.1 /DEF=Homo sapiens, hypothetical protein, clone MGC:782, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:12655084 /UG=Hs.4973 hypothetical protein /FL=gb:BC001393.1 BC001393 cyclin Pas1/PHO80 domain containing 1 CNPPD1 27013 NM_015680 /// XM_005246462 /// XM_005246463 /// XM_006712419 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019901 // protein kinase binding // inferred from electronic annotation 200071_at BF224259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224259 /FEA=EST /DB_XREF=gi:11131523 /DB_XREF=est:7q85c09.x1 /CLONE=IMAGE:3705208 /UG=Hs.79968 splicing factor 30, survival of motor neuron-related /FL=gb:AF083385.1 gb:AF107463.1 gb:NM_005871.1 BF224259 survival motor neuron domain containing 1 SMNDC1 10285 NM_005871 /// XM_005269382 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200072_s_at AF061832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061832.1 /DEF=Homo sapiens M4 protein deletion mutant mRNA, complete cds. /FEA=mRNA /PROD=M4 protein deletion mutant /DB_XREF=gi:3126877 /UG=Hs.79024 heterogeneous nuclear ribonucleoprotein M /FL=gb:AF061832.1 AF061832 heterogeneous nuclear ribonucleoprotein M HNRNPM 4670 NM_001297418 /// NM_005968 /// NM_031203 /// XM_005272478 /// XM_005272479 /// XM_005272480 /// XM_005272481 /// XM_005272482 /// XM_005272483 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200073_s_at M94630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M94630.1 /DEF=Homo sapiens hnRNP-C like protein mRNA, complete cds. /FEA=mRNA /PROD=DNA-binding protein /DB_XREF=gi:181913 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:M94630.1 M94630 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200074_s_at U16738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16738.1 /DEF=Homo sapiens CAG-isl 7 mRNA, complete cds. /FEA=mRNA /PROD=CAG-isl 7 /DB_XREF=gi:608516 /UG=Hs.738 ribosomal protein L14 /FL=gb:U16738.1 U16738 ribosomal protein L14 RPL14 9045 NM_001034996 /// NM_003973 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200075_s_at BC006249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006249.1 /DEF=Homo sapiens, guanylate kinase 1, clone MGC:10618, mRNA, complete cds. /FEA=mRNA /PROD=guanylate kinase 1 /DB_XREF=gi:13623296 /FL=gb:BC006249.1 BC006249 guanylate kinase 1 GUK1 2987 NM_000858 /// NM_001159390 /// NM_001159391 /// NM_001242839 /// NM_001242840 /// XM_005273103 /// XM_005273104 /// XM_005273105 /// XM_005273106 0006163 // purine nucleotide metabolic process // inferred from direct assay /// 0006185 // dGDP biosynthetic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017144 // drug metabolic process // traceable author statement /// 0019673 // GDP-mannose metabolic process // inferred from electronic annotation /// 0034436 // glycoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046037 // GMP metabolic process // inferred from electronic annotation /// 0046054 // dGMP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046711 // GDP biosynthetic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004385 // guanylate kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200076_s_at BC006479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006479.1 /DEF=Homo sapiens, hypothetical protein MGC2749, clone MGC:4376, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein MGC2749 /DB_XREF=gi:13623702 /FL=gb:BC006479.1 BC006479 KxDL motif containing 1 KXD1 79036 NM_001171948 /// NM_001171949 /// NM_024069 /// XM_005260073 /// XM_006722883 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity 0031083 // BLOC-1 complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 200077_s_at D87914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87914.1 /DEF=Human mRNA for ornithine decarboxylase antizyme, complete cds. /FEA=mRNA /GEN=hAZ-brain /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:1590807 /FL=gb:D87914.1 D87914 ornithine decarboxylase antizyme 1 OAZ1 4946 NM_004152 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 200078_s_at BC005876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005876.1 /DEF=Homo sapiens, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD, clone MGC:4498, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 21kD /DB_XREF=gi:13543437 /FL=gb:BC005876.1 BC005876 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b ATP6V0B 533 NM_001039457 /// NM_001294333 /// NM_004047 /// XM_005270944 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 200079_s_at AF285758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF285758.1 /DEF=Homo sapiens lysyl-tRNA synthetase mRNA, complete cds; nuclear gene for mitochondrial product; alternatively spliced. /FEA=CDS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:11095908 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:AF285758.1 AF285758 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200080_s_at AI955655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI955655 /FEA=EST /DB_XREF=gi:5747965 /DB_XREF=est:wt36f03.x1 /CLONE=IMAGE:2509565 /UG=Hs.181307 H3 histone, family 3A AI955655 H3 histone, family 3A /// H3 histone, family 3A, pseudogene 4 /// H3 histone, family 3B (H3.3B) H3F3A /// H3F3AP4 /// H3F3B 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200081_s_at BE741754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE741754 /FEA=EST /DB_XREF=gi:10155746 /DB_XREF=est:601595220F1 /CLONE=IMAGE:3949109 /UG=Hs.241507 ribosomal protein S6 BE741754 ribosomal protein S6 RPS6 6194 NM_001010 0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200082_s_at AI805587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI805587 /FEA=EST /DB_XREF=gi:5392153 /DB_XREF=est:tx97a02.x1 /CLONE=IMAGE:2277482 /UG=Hs.301547 ribosomal protein S7 AI805587 ribosomal protein S7 RPS7 6201 NM_001011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030686 // 90S preribosome // not recorded /// 0032040 // small-subunit processome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200083_at AA621731 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA621731 /FEA=EST /DB_XREF=gi:2525670 /DB_XREF=est:af54h05.s1 /CLONE=IMAGE:1035513 /UG=Hs.12064 ubiquitin specific protease 22 AA621731 ubiquitin specific peptidase 22 USP22 23326 NM_015276 /// XM_005256575 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200084_at BE748698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE748698 /FEA=EST /DB_XREF=gi:10162690 /DB_XREF=est:601571740T1 /CLONE=IMAGE:3838712 /UG=Hs.78050 small acidic protein BE748698 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 200085_s_at NM_007108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007108.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) (TCEB2), mRNA. /FEA=CDS /GEN=TCEB2 /PROD=elongin B /DB_XREF=gi:6005889 /UG=Hs.172772 transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) /FL=gb:NM_007108.1 gb:L42856.1 NM_007108 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) TCEB2 6923 NM_007108 /// NM_207013 /// XM_006720937 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070449 // elongin complex // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 200086_s_at AA854966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA854966 /FEA=EST /DB_XREF=gi:2942504 /DB_XREF=est:aj70d12.s1 /CLONE=IMAGE:1401815 /UG=Hs.113205 cytochrome c oxidase subunit IV AA854966 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 /// XM_005255798 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200087_s_at AK024976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024976.1 /DEF=Homo sapiens cDNA: FLJ21323 fis, clone COL02374. /FEA=mRNA /DB_XREF=gi:10437405 /UG=Hs.75914 Homo sapiens cDNA: FLJ21323 fis, clone COL02374 AK024976 transmembrane emp24 domain trafficking protein 2 TMED2 10959 NM_006815 /// XM_005253544 0001893 // maternal placenta development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0035459 // cargo loading into vesicle // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200088_x_at AK026491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026491.1 /DEF=Homo sapiens cDNA: FLJ22838 fis, clone KAIA4494, highly similar to HUML12A Human ribosomal protein L12 mRNA. /FEA=mRNA /DB_XREF=gi:10439364 /UG=Hs.182979 ribosomal protein L12 AK026491 neurobeachin-like 1 /// ribosomal protein L12 NBEAL1 /// RPL12 6136 /// 65065 NM_000976 /// NM_001099273 /// NM_001114132 /// NM_198945 /// NM_205543 /// XM_005246787 /// XM_005246788 /// XM_006712698 /// XM_006712699 /// XM_006712700 /// XM_006712701 /// XM_006712702 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200089_s_at AI953886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI953886 /FEA=EST /DB_XREF=gi:5746196 /DB_XREF=est:wx70g02.x1 /CLONE=IMAGE:2549042 /UG=Hs.286 ribosomal protein L4 AI953886 ribosomal protein L4 /// small nucleolar RNA, C/D box 16 /// small nucleolar RNA, C/D box 18A /// small nucleolar RNA, C/D box 18B /// small nucleolar RNA, C/D box 18C RPL4 /// SNORD16 /// SNORD18A /// SNORD18B /// SNORD18C 6124 /// 595097 /// 595098 /// 595099 /// 595100 NM_000968 /// NR_002440 /// NR_002441 /// NR_002442 /// NR_002443 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200090_at BG168896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG168896 /FEA=EST /DB_XREF=gi:12675599 /DB_XREF=est:602320235F1 /CLONE=IMAGE:4415240 /UG=Hs.138381 farnesyltransferase, CAAX box, alpha BG168896 farnesyltransferase, CAAX box, alpha FNTA 2339 NM_001018676 /// NM_001018677 /// NM_002027 /// NR_033698 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018343 // protein farnesylation // inferred from direct assay /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0090044 // positive regulation of tubulin deacetylation // inferred from direct assay /// 0090045 // positive regulation of deacetylase activity // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005953 // CAAX-protein geranylgeranyltransferase complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0004661 // protein geranylgeranyltransferase activity // inferred from direct assay /// 0004662 // CAAX-protein geranylgeranyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 200091_s_at AA888388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA888388 /FEA=EST /DB_XREF=gi:3004063 /DB_XREF=est:nw79f03.s1 /CLONE=IMAGE:1252829 /UG=Hs.113029 ribosomal protein S25 AA888388 ribosomal protein S25 RPS25 6230 NM_001028 0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200092_s_at BF216701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF216701 /FEA=EST /DB_XREF=gi:11110287 /DB_XREF=est:601884615F1 /CLONE=IMAGE:4103235 /UG=Hs.179779 ribosomal protein L37 BF216701 ribosomal protein L37 RPL37 6167 NM_000997 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200093_s_at N32864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32864 /FEA=EST /DB_XREF=gi:1153263 /DB_XREF=est:yw88d08.s1 /CLONE=IMAGE:259311 /UG=Hs.256697 histidine triad nucleotide-binding protein N32864 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 /// NR_073488 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009154 // purine ribonucleotide catabolic process // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from direct assay 200094_s_at AI004246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI004246 /FEA=EST /DB_XREF=gi:3213756 /DB_XREF=est:ou03g06.x1 /CLONE=IMAGE:1625242 /UG=Hs.75309 eukaryotic translation elongation factor 2 AI004246 eukaryotic translation elongation factor 2 EEF2 1938 NM_001961 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008494 // translation activator activity // inferred from genetic interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200095_x_at AA320764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA320764 /FEA=EST /DB_XREF=gi:1973113 /DB_XREF=est:EST23183 /UG=Hs.76230 ribosomal protein S10 AA320764 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 200096_s_at AI862255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI862255 /FEA=EST /DB_XREF=gi:5526362 /DB_XREF=est:tb77d10.x1 /CLONE=IMAGE:2060371 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD AI862255 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 200097_s_at AI701949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI701949 /FEA=EST /DB_XREF=gi:4989849 /DB_XREF=est:tq09c07.x1 /CLONE=IMAGE:2208300 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K AI701949 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 /// XM_005251960 /// XM_005251961 /// XM_005251963 /// XM_005251964 /// XM_005251965 /// XM_005251966 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200098_s_at T33068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T33068 /FEA=EST /DB_XREF=gi:615166 /DB_XREF=est:EST56576 /UG=Hs.7101 anaphase-promoting complex subunit 5 T33068 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 /// XM_005253900 /// XM_006719449 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 200099_s_at AL356115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL356115 /DEF=Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands /FEA=CDS_1 /DB_XREF=gi:9795038 /UG=Hs.307132 Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands AL356115 ribosomal protein S3A /// small nucleolar RNA, C/D box 73A RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200593_s_at BC003621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003621.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A), clone MGC:1992, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:13177672 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1 BC003621 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200594_x_at NM_004501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004501.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRPU), mRNA. /FEA=mRNA /GEN=HNRPU /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:4758545 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1 NM_004501 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200595_s_at NM_003750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003750.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) (EIF3S10), mRNA. /FEA=mRNA /GEN=EIF3S10 /PROD=eukaryotic translation initiation factor 3,subunit 10 (theta, 150170kD) /DB_XREF=gi:4503508 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 NM_003750 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200596_s_at BE614908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE614908 /FEA=EST /DB_XREF=gi:9896507 /DB_XREF=est:601280348F1 /CLONE=IMAGE:3622499 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 BE614908 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200597_at AI123320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123320 /FEA=EST /DB_XREF=gi:3539086 /DB_XREF=est:qa48a10.x1 /CLONE=IMAGE:1689978 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 AI123320 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200598_s_at AI582238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI582238 /FEA=EST /DB_XREF=gi:4568135 /DB_XREF=est:tq65c10.x1 /CLONE=IMAGE:2213682 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1 AI582238 heat shock protein 90kDa beta (Grp94), member 1 /// microRNA 3652 HSP90B1 /// MIR3652 7184 /// 100500842 NM_003299 /// NR_037425 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200599_s_at NM_003299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003299.1 /DEF=Homo sapiens tumor rejection antigen (gp96) 1 (TRA1), mRNA. /FEA=mRNA /GEN=TRA1 /PROD=tumor rejection antigen (gp96) 1 /DB_XREF=gi:4507676 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1 NM_003299 heat shock protein 90kDa beta (Grp94), member 1 /// microRNA 3652 HSP90B1 /// MIR3652 7184 /// 100500842 NM_003299 /// NR_037425 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200600_at NM_002444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002444.1 /DEF=Homo sapiens moesin (MSN), mRNA. /FEA=mRNA /GEN=MSN /PROD=moesin /DB_XREF=gi:4505256 /UG=Hs.170328 moesin /FL=gb:M69066.1 gb:NM_002444.1 NM_002444 moesin MSN 4478 NM_002444 /// XM_005262269 0006928 // cellular component movement // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0050900 // leukocyte migration // inferred from expression pattern /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 2000401 // regulation of lymphocyte migration // inferred from mutant phenotype 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 200601_at U48734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U48734.1 /DEF=Human non-muscle alpha-actinin mRNA, complete cds. /FEA=mRNA /PROD=alpha actinin /DB_XREF=gi:3157975 /UG=Hs.182485 actinin, alpha 4 /FL=gb:NM_004924.2 gb:BC005033.1 gb:D89980.1 gb:U48734.1 U48734 actinin, alpha 4 ACTN4 81 NM_004924 /// XM_005259281 /// XM_005259282 /// XM_006723406 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032417 // positive regulation of sodium:proton antiporter activity // non-traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048549 // positive regulation of pinocytosis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051272 // positive regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001882 // nucleoside binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 200602_at NM_000484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000484.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) (APP), mRNA. /FEA=mRNA /GEN=APP /PROD=amyloid beta (A4) precursor protein (proteasenexin-II, Alzheimer disease) /DB_XREF=gi:4502166 /UG=Hs.177486 amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) /FL=gb:NM_000484.1 NM_000484 amyloid beta (A4) precursor protein APP 351 NM_000484 /// NM_001136016 /// NM_001136129 /// NM_001136130 /// NM_001136131 /// NM_001204301 /// NM_001204302 /// NM_001204303 /// NM_201413 /// NM_201414 0000085 // mitotic G2 phase // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007617 // mating behavior // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008088 // axon cargo transport // inferred from sequence or structural similarity /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048669 // collateral sprouting in absence of injury // inferred from sequence or structural similarity /// 0050803 // regulation of synapse structure and activity // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051124 // synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from direct assay /// 0043198 // dendritic shaft // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from electronic annotation 200603_at AL050038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050038.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566J0124 (from clone DKFZp566J0124). /FEA=mRNA /DB_XREF=gi:4884279 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 AL050038 protein kinase, cAMP-dependent, regulatory, type I, alpha PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200604_s_at M18468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M18468.1 /DEF=Human cAMP-dependent protein kinase regulatory subunit type I (PRKAR1A) mRNA, complete cds. /FEA=mRNA /GEN=PRKAR1A /PROD=cAMP-dependent protein kinase regulatory subunittype 1 /DB_XREF=gi:1526988 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 M18468 protein kinase, cAMP-dependent, regulatory, type I, alpha PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200605_s_at NM_002734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002734.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), mRNA. /FEA=mRNA /GEN=PRKAR1A /PROD=protein kinase, cAMP-dependent, regulatory, typeI, alpha /DB_XREF=gi:4506062 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 NM_002734 protein kinase, cAMP-dependent, regulatory, type I, alpha PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200606_at NM_004415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004415.1 /DEF=Homo sapiens desmoplakin (DPI, DPII) (DSP), mRNA. /FEA=mRNA /GEN=DSP /PROD=desmoplakin (DPI, DPII) /DB_XREF=gi:4758199 /UG=Hs.74316 desmoplakin (DPI, DPII) /FL=gb:M77830.3 gb:NM_004415.1 NM_004415 desmoplakin DSP 1832 NM_001008844 /// NM_004415 0002934 // desmosome organization // inferred from sequence or structural similarity /// 0003223 // ventricular compact myocardium morphogenesis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from sequence or structural similarity /// 0071896 // protein localization to adherens junction // inferred from sequence or structural similarity /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from physical interaction /// 0005198 // structural molecule activity // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction 200607_s_at BG289967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289967 /FEA=EST /DB_XREF=gi:13046289 /DB_XREF=est:602381386F1 /CLONE=IMAGE:4499085 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1 BG289967 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200608_s_at NM_006265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006265.1 /DEF=Homo sapiens RAD21 (S. pombe) homolog (RAD21), mRNA. /FEA=mRNA /GEN=RAD21 /PROD=RAD21 (S. pombe) homolog /DB_XREF=gi:5453993 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1 NM_006265 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200609_s_at NM_017491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017491.1 /DEF=Homo sapiens WD repeat domain 1 (WDR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=WDR1 /PROD=WD repeat-containing protein 1, isoform 1 /DB_XREF=gi:9257256 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1 NM_017491 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200610_s_at NM_005381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005381.1 /DEF=Homo sapiens nucleolin (NCL), mRNA. /FEA=mRNA /GEN=NCL /PROD=nucleolin /DB_XREF=gi:4885510 /UG=Hs.79110 nucleolin /FL=gb:NM_005381.1 NM_005381 nucleolin NCL 4691 NM_005381 0001525 // angiogenesis // inferred from direct assay /// 1901838 // positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200611_s_at AB010427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB010427.2 /DEF=Homo sapiens mRNA for NORI-1, complete cds. /FEA=mRNA /PROD=NORI-1 /DB_XREF=gi:5103672 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1 AB010427 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200612_s_at NM_001282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001282.1 /DEF=Homo sapiens adaptor-related protein complex 2, beta 1 subunit (AP2B1), mRNA. /FEA=mRNA /GEN=AP2B1 /PROD=adaptor-related protein complex 2, beta 1subunit /DB_XREF=gi:4557468 /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1 NM_001282 adaptor-related protein complex 2, beta 1 subunit AP2B1 163 NM_001030006 /// NM_001282 /// XM_005257937 /// XM_005257938 /// XM_005257941 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200613_at NM_004068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004068.1 /DEF=Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), mRNA. /FEA=mRNA /GEN=AP2M1 /PROD=adaptor-related protein complex 2, mu 1 subunit /DB_XREF=gi:4757993 /UG=Hs.152936 adaptor-related protein complex 2, mu 1 subunit /FL=gb:U36188.1 gb:BC004996.1 gb:D63475.1 gb:NM_004068.1 NM_004068 adaptor-related protein complex 2, mu 1 subunit AP2M1 1173 NM_001025205 /// NM_004068 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 200614_at NM_004859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004859.1 /DEF=Homo sapiens clathrin, heavy polypeptide (Hc) (CLTC), mRNA. /FEA=mRNA /GEN=CLTC /PROD=clathrin heavy chain /DB_XREF=gi:4758011 /UG=Hs.178710 clathrin, heavy polypeptide (Hc) /FL=gb:D21260.1 gb:NM_004859.1 NM_004859 clathrin, heavy chain (Hc) CLTC 1213 NM_001288653 /// NM_004859 /// XM_005257012 0001649 // osteoblast differentiation // inferred from direct assay /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032051 // clathrin light chain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200615_s_at AL567295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567295 /FEA=EST /DB_XREF=gi:12920509 /DB_XREF=est:AL567295 /CLONE=CS0DF027YO06 (3 prime) /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1 AL567295 adaptor-related protein complex 2, beta 1 subunit AP2B1 163 NM_001030006 /// NM_001282 /// XM_005257937 /// XM_005257938 /// XM_005257941 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200616_s_at BC000371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000371.1 /DEF=Homo sapiens, KIAA0152 gene product, clone MGC:8341, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0152 gene product /DB_XREF=gi:12653206 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1 BC000371 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from sequence or structural similarity 200617_at NM_014730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014730.1 /DEF=Homo sapiens KIAA0152 gene product (KIAA0152), mRNA. /FEA=mRNA /GEN=KIAA0152 /PROD=KIAA0152 gene product /DB_XREF=gi:7661947 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1 NM_014730 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from sequence or structural similarity 200618_at NM_006148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006148.1 /DEF=Homo sapiens LIM and SH3 protein 1 (LASP1), mRNA. /FEA=mRNA /GEN=LASP1 /PROD=LIM and SH3 protein 1 /DB_XREF=gi:5453709 /UG=Hs.75080 LIM and SH3 protein 1 /FL=gb:NM_006148.1 NM_006148 LIM and SH3 protein 1 LASP1 3927 NM_001271608 /// NM_006148 /// NR_073384 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 200619_at NM_006842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006842.1 /DEF=Homo sapiens splicing factor 3b, subunit 2, 145kD (SF3B2), mRNA. /FEA=mRNA /GEN=SF3B2 /PROD=splicing factor 3b, subunit 2, 145kD /DB_XREF=gi:5803154 /UG=Hs.75916 splicing factor 3b, subunit 2, 145kD /FL=gb:U41371.1 gb:NM_006842.1 NM_006842 splicing factor 3b, subunit 2, 145kDa SF3B2 10992 NM_006842 /// XM_005273726 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200620_at NM_004872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004872.1 /DEF=Homo sapiens chromosome 1 open reading frame 8 (C1ORF8), mRNA. /FEA=mRNA /GEN=C1ORF8 /PROD=chromosome 1 open reading frame 8 /DB_XREF=gi:4758571 /UG=Hs.11441 chromosome 1 open reading frame 8 /FL=gb:BC003106.1 gb:AF290615.1 gb:AF047439.1 gb:NM_004872.1 NM_004872 transmembrane protein 59 TMEM59 9528 NM_004872 /// XM_005271350 /// XM_005271351 /// XM_006711051 0006508 // proteolysis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0010955 // negative regulation of protein processing // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090285 // negative regulation of protein glycosylation in Golgi // inferred from direct assay 0000137 // Golgi cis cisterna // inferred from direct assay /// 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005797 // Golgi medial cisterna // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200621_at NM_004078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004078.1 /DEF=Homo sapiens cysteine and glycine-rich protein 1 (CSRP1), mRNA. /FEA=mRNA /GEN=CSRP1 /PROD=cysteine and glycine-rich protein 1 /DB_XREF=gi:4758085 /UG=Hs.108080 cysteine and glycine-rich protein 1 /FL=gb:M33146.1 gb:NM_004078.1 NM_004078 cysteine and glycine-rich protein 1 CSRP1 1465 NM_001144773 /// NM_001193570 /// NM_001193571 /// NM_001193572 /// NM_004078 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200622_x_at AV685208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV685208 /FEA=EST /DB_XREF=gi:10287071 /DB_XREF=est:AV685208 /CLONE=GKCCXA06 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1 AV685208 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200623_s_at NM_005184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005184.1 /DEF=Homo sapiens calmodulin 3 (phosphorylase kinase, delta) (CALM3), mRNA. /FEA=mRNA /GEN=CALM3 /PROD=calmodulin 3 (phosphorylase kinase, delta) /DB_XREF=gi:4885108 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1 NM_005184 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200624_s_at AA577695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA577695 /FEA=EST /DB_XREF=gi:2355879 /DB_XREF=est:nn22h02.s1 /CLONE=IMAGE:1084659 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1 AA577695 matrin 3 /// small nucleolar RNA host gene 4 (non-protein coding) MATR3 /// SNHG4 9782 /// 724102 NM_001194954 /// NM_001194955 /// NM_001194956 /// NM_001282278 /// NM_018834 /// NM_199189 /// NR_003141 /// NR_036536 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200625_s_at NM_006367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006367.2 /DEF=Homo sapiens adenylyl cyclase-associated protein (CAP), mRNA. /FEA=mRNA /GEN=CAP /PROD=adenylyl cyclase-associated protein /DB_XREF=gi:10938021 /UG=Hs.104125 adenylyl cyclase-associated protein /FL=gb:NM_006367.2 gb:L12168.1 gb:M98474.1 NM_006367 CAP, adenylate cyclase-associated protein 1 (yeast) CAP1 10487 NM_001105530 /// NM_006367 /// XM_005270367 /// XM_005270368 /// XM_006710294 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200626_s_at NM_018834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018834.1 /DEF=Homo sapiens matrin 3 (MATR3), mRNA. /FEA=mRNA /GEN=MATR3 /PROD=matrin 3 /DB_XREF=gi:10047081 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1 NM_018834 matrin 3 /// small nucleolar RNA host gene 4 (non-protein coding) MATR3 /// SNHG4 9782 /// 724102 NM_001194954 /// NM_001194955 /// NM_001194956 /// NM_001282278 /// NM_018834 /// NM_199189 /// NR_003141 /// NR_036536 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200627_at BC003005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003005.1 /DEF=Homo sapiens, unactive progesterone receptor, 23 kD, clone MGC:4004, mRNA, complete cds. /FEA=mRNA /PROD=unactive progesterone receptor, 23 kD /DB_XREF=gi:12804292 /UG=Hs.278270 unactive progesterone receptor, 23 kD /FL=gb:BC003005.1 gb:L24804.1 gb:NM_006601.1 BC003005 prostaglandin E synthase 3 (cytosolic) PTGES3 10728 NM_001282601 /// NM_001282602 /// NM_001282603 /// NM_001282604 /// NM_001282605 /// NM_006601 /// NR_104219 /// XM_005268576 /// XM_006719199 /// XR_245889 /// XR_429072 0000723 // telomere maintenance // traceable author statement /// 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0006278 // RNA-dependent DNA replication // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0000781 // chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003720 // telomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0050220 // prostaglandin-E synthase activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 200628_s_at M61715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M61715.1 /DEF=Human tryptophanyl-tRNA synthetase (WRS) mRNA, complete cds. /FEA=mRNA /GEN=WARS /PROD=transfer RNA-Trp synthetase /DB_XREF=gi:340367 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2 M61715 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 /// XM_005268044 /// XM_006720248 /// XM_006720249 0001525 // angiogenesis // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // non-traceable author statement /// 0004830 // tryptophan-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200629_at NM_004184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004184.2 /DEF=Homo sapiens tryptophanyl-tRNA synthetase (WARS), mRNA. /FEA=mRNA /GEN=WARS /PROD=tryptophanyl-tRNA synthetase /DB_XREF=gi:7710155 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2 NM_004184 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 /// XM_005268044 /// XM_006720248 /// XM_006720249 0001525 // angiogenesis // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // non-traceable author statement /// 0004830 // tryptophan-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200630_x_at AV702810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702810 /FEA=EST /DB_XREF=gi:10719140 /DB_XREF=est:AV702810 /CLONE=ADBDGH01 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1 AV702810 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200631_s_at NM_003011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003011.1 /DEF=Homo sapiens SET translocation (myeloid leukemia-associated) (SET), mRNA. /FEA=mRNA /GEN=SET /PROD=SET translocation (myeloid leukemia-associated) /DB_XREF=gi:4506890 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1 NM_003011 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200632_s_at NM_006096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006096.1 /DEF=Homo sapiens N-myc downstream regulated (NDRG1), mRNA. /FEA=mRNA /GEN=NDRG1 /PROD=N-myc downstream regulated /DB_XREF=gi:5174656 /UG=Hs.75789 N-myc downstream regulated /FL=gb:BC003175.1 gb:D87953.1 gb:AF004162.1 gb:NM_006096.1 NM_006096 N-myc downstream regulated 1 NDRG1 10397 NM_001135242 /// NM_001258432 /// NM_001258433 /// NM_006096 0008219 // cell death // inferred from electronic annotation /// 0010038 // response to metal ion // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from expression pattern /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0045576 // mast cell activation // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090232 // positive regulation of spindle checkpoint // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0043015 // gamma-tubulin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from direct assay 200633_at NM_018955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018955.1 /DEF=Homo sapiens ubiquitin B (UBB), mRNA. /FEA=mRNA /GEN=UBB /PROD=ubiquitin B /DB_XREF=gi:11024713 /UG=Hs.183842 ubiquitin B /FL=gb:NM_018955.1 gb:BC000379.1 NM_018955 ubiquitin B UBB 7314 NM_001281716 /// NM_001281717 /// NM_001281718 /// NM_001281719 /// NM_001281720 /// NM_018955 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 200634_at NM_005022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005022.1 /DEF=Homo sapiens profilin 1 (PFN1), mRNA. /FEA=mRNA /GEN=PFN1 /PROD=profilin 1 /DB_XREF=gi:4826897 /UG=Hs.75721 profilin 1 /FL=gb:BC002475.1 gb:J03191.1 gb:NM_005022.1 NM_005022 profilin 1 PFN1 5216 NM_005022 0001843 // neural tube closure // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030837 // negative regulation of actin filament polymerization // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from genetic interaction /// 0032232 // negative regulation of actin filament bundle assembly // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900029 // positive regulation of ruffle assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000774 // adenyl-nucleotide exchange factor activity // inferred from direct assay /// 0003779 // actin binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 200635_s_at AU145351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145351 /FEA=EST /DB_XREF=gi:11006872 /DB_XREF=est:AU145351 /CLONE=HEMBA1004591 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 AU145351 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200636_s_at NM_002840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002840.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, F (PTPRF), mRNA. /FEA=mRNA /GEN=PTPRF /PROD=protein tyrosine phosphatase, receptor type, fpolypeptide /DB_XREF=gi:4506310 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 NM_002840 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200637_s_at AI762627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762627 /FEA=EST /DB_XREF=gi:5178294 /DB_XREF=est:wi56g01.x1 /CLONE=IMAGE:2394288 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 AI762627 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200638_s_at BC003623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003623.1 /DEF=Homo sapiens, tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide, clone MGC:2153, mRNA, complete cds. /FEA=mRNA /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:13177678 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 BC003623 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200639_s_at NM_003406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 NM_003406 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200640_at NM_003406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 NM_003406 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200641_s_at U28964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U28964.1 /DEF=Homo sapiens 14-3-3 protein mRNA, complete cds. /FEA=mRNA /PROD=14-3-3 protein /DB_XREF=gi:899458 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 U28964 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200642_at NM_000454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000454.1 /DEF=Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA. /FEA=mRNA /GEN=SOD1 /PROD=superoxide dismutase 1, soluble (amyotrophiclateral sclerosis 1 (adult)) /DB_XREF=gi:4507148 /UG=Hs.75428 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) /FL=gb:BC001034.1 gb:K00065.1 gb:NM_000454.1 NM_000454 superoxide dismutase 1, soluble SOD1 6647 NM_000454 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0001890 // placenta development // non-traceable author statement /// 0001895 // retina homeostasis // inferred from sequence or structural similarity /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006879 // cellular iron ion homeostasis // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0007566 // embryo implantation // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0010033 // response to organic substance // inferred from direct assay /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0019430 // removal of superoxide radicals // not recorded /// 0019430 // removal of superoxide radicals // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032287 // peripheral nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0033081 // regulation of T cell differentiation in thymus // non-traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from sequence or structural similarity /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred by curator /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046620 // regulation of organ growth // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048538 // thymus development // non-traceable author statement /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0050665 // hydrogen peroxide biosynthetic process // inferred from direct assay /// 0050665 // hydrogen peroxide biosynthetic process // inferred from sequence or structural similarity /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060047 // heart contraction // inferred from direct assay /// 0060052 // neurofilament cytoskeleton organization // inferred from sequence or structural similarity /// 0060087 // relaxation of vascular smooth muscle // inferred from sequence or structural similarity /// 0060088 // auditory receptor cell stereocilium organization // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 1902177 // positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0032839 // dendrite cytoplasm // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004784 // superoxide dismutase activity // not recorded /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 200643_at NM_005336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005336.1 /DEF=Homo sapiens high density lipoprotein binding protein (vigilin) (HDLBP), mRNA. /FEA=mRNA /GEN=HDLBP /PROD=high density lipoprotein binding protein /DB_XREF=gi:4885408 /UG=Hs.177516 high density lipoprotein binding protein (vigilin) /FL=gb:BC001179.1 gb:M64098.1 gb:NM_005336.1 NM_005336 high density lipoprotein binding protein HDLBP 3069 NM_001243900 /// NM_005336 /// NM_203346 /// XM_005247000 /// XM_005247001 /// XM_005247002 /// XM_005247003 /// XM_006712475 /// XM_006712476 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200644_at NM_023009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023009.1 /DEF=Homo sapiens macrophage myristoylated alanine-rich C kinase substrate (MACMARCKS), mRNA. /FEA=mRNA /GEN=MACMARCKS /PROD=macrophage myristoylated alanine-rich C kinasesubstrate /DB_XREF=gi:13491173 /UG=Hs.75061 macrophage myristoylated alanine-rich C kinase substrate /FL=gb:NM_023009.1 NM_023009 MARCKS-like 1 MARCKSL1 65108 NM_023009 /// NR_052852 0008284 // positive regulation of cell proliferation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 200645_at NM_007278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007278.1 /DEF=Homo sapiens GABA(A) receptor-associated protein (GABARAP), mRNA. /FEA=mRNA /GEN=GABARAP /PROD=GABA(A) receptor-associated protein /DB_XREF=gi:6005763 /UG=Hs.7719 GABA(A) receptor-associated protein /FL=gb:AB030711.1 gb:AF044671.1 gb:AF067171.1 gb:AF161586.1 gb:NM_007278.1 gb:AF183425.1 NM_007278 GABA(A) receptor-associated protein GABARAP 11337 NM_007278 0000045 // autophagic vacuole assembly // not recorded /// 0000226 // microtubule cytoskeleton organization // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006605 // protein targeting // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from physical interaction 200646_s_at NM_006184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006184.1 /DEF=Homo sapiens nucleobindin 1 (NUCB1), mRNA. /FEA=mRNA /GEN=NUCB1 /PROD=nucleobindin 1 /DB_XREF=gi:5453817 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1 NM_006184 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200647_x_at NM_003752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003752.2 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 8 (110kD) (EIF3S8), mRNA. /FEA=mRNA /GEN=EIF3S8 /PROD=eukaryotic translation initiation factor 3,subunit 8 (110kD) /DB_XREF=gi:5579457 /UG=Hs.4835 eukaryotic translation initiation factor 3, subunit 8 (110kD) /FL=gb:NM_003752.2 NM_003752 eukaryotic translation initiation factor 3, subunit C /// eukaryotic translation initiation factor 3, subunit C-like EIF3C /// EIF3CL 8663 /// 728689 NM_001037808 /// NM_001099661 /// NM_001199142 /// NM_001267574 /// NM_001286478 /// NM_003752 /// XM_005255535 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200648_s_at NM_002065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002065.1 /DEF=Homo sapiens glutamate-ammonia ligase (glutamine synthase) (GLUL), mRNA. /FEA=mRNA /GEN=GLUL /PROD=glutamate-ammonia ligase (glutamine synthase) /DB_XREF=gi:4504026 /UG=Hs.170171 glutamate-ammonia ligase (glutamine synthase) /FL=gb:NM_002065.1 NM_002065 glutamate-ammonia ligase GLUL 2752 NM_001033044 /// NM_001033056 /// NM_002065 /// XM_006711278 0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006542 // glutamine biosynthetic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045503 // dynein light chain binding // inferred from electronic annotation 200649_at BC002356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002356.1 /DEF=Homo sapiens, nucleobindin 1, clone MGC:8479, mRNA, complete cds. /FEA=mRNA /PROD=nucleobindin 1 /DB_XREF=gi:12803104 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1 BC002356 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200650_s_at NM_005566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005566.1 /DEF=Homo sapiens lactate dehydrogenase A (LDHA), mRNA. /FEA=mRNA /GEN=LDHA /PROD=LDHA /DB_XREF=gi:5031856 /UG=Hs.2795 lactate dehydrogenase A /FL=gb:BC001829.1 gb:NM_005566.1 NM_005566 lactate dehydrogenase A LDHA 3939 NM_001135239 /// NM_001165414 /// NM_001165415 /// NM_001165416 /// NM_005566 /// NR_028500 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // non-traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 200651_at NM_006098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006098.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1), mRNA. /FEA=mRNA /GEN=GNB2L1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2-like 1 /DB_XREF=gi:5174446 /UG=Hs.5662 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /FL=gb:BC000214.1 gb:BC000366.1 gb:BC000672.1 gb:M24194.1 gb:NM_006098.1 NM_006098 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /// small nucleolar RNA, C/D box 95 /// small nucleolar RNA, C/D box 96A GNB2L1 /// SNORD95 /// SNORD96A 10399 /// 619570 /// 619571 NM_006098 /// NR_002591 /// NR_002592 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030822 // positive regulation of cAMP catabolic process // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from mutant phenotype /// 0051302 // regulation of cell division // inferred from sequence or structural similarity /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051901 // positive regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from electronic annotation /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from genetic interaction /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0001891 // phagocytic cup // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from direct assay /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008200 // ion channel inhibitor activity // inferred from sequence or structural similarity /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay /// 0032947 // protein complex scaffold // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200652_at NM_003145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003145.2 /DEF=Homo sapiens signal sequence receptor, beta (translocon-associated protein beta) (SSR2), mRNA. /FEA=mRNA /GEN=SSR2 /PROD=signal sequence receptor, beta precursor /DB_XREF=gi:6552341 /UG=Hs.74564 signal sequence receptor, beta (translocon-associated protein beta) /FL=gb:D37991.1 gb:BC000341.1 gb:NM_003145.2 NM_003145 signal sequence receptor, beta (translocon-associated protein beta) SSR2 6746 NM_003145 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200653_s_at M27319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M27319.1 /DEF=Human calmodulin mRNA, complete cds. /FEA=mRNA /PROD=calmodulin /DB_XREF=gi:179809 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1 M27319 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200654_at J02783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02783.1 /DEF=Human thyroid hormone binding protein (p55) mRNA, complete cds. /FEA=mRNA /GEN=P4HB /DB_XREF=gi:339646 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1 J02783 prolyl 4-hydroxylase, beta polypeptide P4HB 5034 NM_000918 0006457 // protein folding // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016222 // procollagen-proline 4-dioxygenase complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 200655_s_at NM_006888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006888.1 /DEF=Homo sapiens calmodulin 1 (phosphorylase kinase, delta) (CALM1), mRNA. /FEA=mRNA /GEN=CALM1 /PROD=calmodulin 1 (phosphorylase kinase, delta) /DB_XREF=gi:5901911 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1 NM_006888 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200656_s_at NM_000918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000918.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) (P4HB), mRNA. /FEA=mRNA /GEN=P4HB /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), beta polypeptide(protein disulfide isomerase; thyroid hormone bindingprotein p55) /DB_XREF=gi:4505566 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1 NM_000918 prolyl 4-hydroxylase, beta polypeptide P4HB 5034 NM_000918 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016222 // procollagen-proline 4-dioxygenase complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 200657_at NM_001152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001152.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (SLC25A5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A5 /PROD=solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 5 /DB_XREF=gi:4502098 /UG=Hs.79172 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 /FL=gb:J02683.1 gb:NM_001152.1 NM_001152 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 SLC25A5 292 NM_001152 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0015853 // adenine transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071817 // MMXD complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015207 // adenine transmembrane transporter activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200658_s_at AL560017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL560017 /FEA=EST /DB_XREF=gi:12906073 /DB_XREF=est:AL560017 /CLONE=CS0DG004YD08 (5 prime) /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2 AL560017 prohibitin PHB 5245 NM_001281496 /// NM_001281497 /// NM_001281715 /// NM_002634 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0071354 // cellular response to interleukin-6 // inferred from direct assay /// 0071897 // DNA biosynthetic process // inferred from electronic annotation /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 200659_s_at NM_002634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002634.2 /DEF=Homo sapiens prohibitin (PHB), mRNA. /FEA=mRNA /GEN=PHB /PROD=prohibitin /DB_XREF=gi:6031190 /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2 NM_002634 prohibitin PHB 5245 NM_001281496 /// NM_001281497 /// NM_001281715 /// NM_002634 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0071354 // cellular response to interleukin-6 // inferred from direct assay /// 0071897 // DNA biosynthetic process // inferred from electronic annotation /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 200660_at NM_005620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005620.1 /DEF=Homo sapiens S100 calcium-binding protein A11 (calgizzarin) (S100A11), mRNA. /FEA=mRNA /GEN=S100A11 /PROD=S100 calcium-binding protein A11 /DB_XREF=gi:5032056 /UG=Hs.256290 S100 calcium-binding protein A11 (calgizzarin) /FL=gb:D49355.1 gb:BC001410.1 gb:D50374.1 gb:NM_005620.1 gb:D38583.1 NM_005620 S100 calcium binding protein A11 S100A11 6282 NM_005620 0007165 // signal transduction // traceable author statement /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay 200661_at NM_000308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000308.1 /DEF=Homo sapiens protective protein for beta-galactosidase (galactosialidosis) (PPGB), mRNA. /FEA=mRNA /GEN=PPGB /PROD=protective protein for beta-galactosidase /DB_XREF=gi:4505988 /UG=Hs.118126 protective protein for beta-galactosidase (galactosialidosis) /FL=gb:BC000597.1 gb:M22960.1 gb:NM_000308.1 NM_000308 cathepsin A CTSA 5476 NM_000308 /// NM_001127695 /// NM_001167594 0006508 // proteolysis // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030239 // myofibril assembly // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030891 // VCB complex // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200662_s_at NM_014765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014765.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 20 (yeast) homolog (KIAA0016), mRNA. /FEA=mRNA /GEN=KIAA0016 /PROD=translocase of outer mitochondrial membrane 20(yeast) homolog /DB_XREF=gi:7657256 /UG=Hs.75187 translocase of outer mitochondrial membrane 20 (yeast) homolog /FL=gb:BC000882.1 gb:D13641.1 gb:NM_014765.1 NM_014765 translocase of outer mitochondrial membrane 20 homolog (yeast) TOMM20 9804 NM_014765 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // non-traceable author statement /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 200663_at NM_001780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001780.1 /DEF=Homo sapiens CD63 antigen (melanoma 1 antigen) (CD63), mRNA. /FEA=mRNA /GEN=CD63 /PROD=CD63 antigen (melanoma 1 antigen) /DB_XREF=gi:4502678 /UG=Hs.76294 CD63 antigen (melanoma 1 antigen) /FL=gb:BC002349.1 gb:M59907.1 gb:NM_001780.1 NM_001780 CD63 molecule CD63 967 NM_001040034 /// NM_001257389 /// NM_001257390 /// NM_001257391 /// NM_001257392 /// NM_001257400 /// NM_001257401 /// NM_001267698 /// NM_001780 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0034613 // cellular protein localization // inferred from direct assay /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0048757 // pigment granule maturation // inferred from mutant phenotype /// 1900746 // regulation of vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 2000680 // regulation of rubidium ion transport // inferred from direct assay /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097487 // multivesicular body, internal vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200664_s_at BG537255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG537255 /FEA=EST /DB_XREF=gi:13529117 /DB_XREF=est:602565318F1 /CLONE=IMAGE:4689748 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1 BG537255 DnaJ (Hsp40) homolog, subfamily B, member 1 DNAJB1 3337 NM_006145 /// XM_006722733 /// XM_006722734 /// XM_006722735 /// XM_006722736 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 200665_s_at NM_003118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003118.1 /DEF=Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin) (SPARC), mRNA. /FEA=mRNA /GEN=SPARC /PROD=secreted protein, acidic, cysteine-rich(osteonectin) /DB_XREF=gi:4507170 /UG=Hs.111779 secreted protein, acidic, cysteine-rich (osteonectin) /FL=gb:BC004974.1 gb:J03040.1 gb:NM_003118.1 NM_003118 secreted protein, acidic, cysteine-rich (osteonectin) SPARC 6678 NM_003118 0001503 // ossification // inferred from electronic annotation /// 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // non-traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005518 // collagen binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 200666_s_at NM_006145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006145.1 /DEF=Homo sapiens heat shock 40kD protein 1 (HSPF1), mRNA. /FEA=mRNA /GEN=HSPF1 /PROD=heat shock 40kD protein 1 /DB_XREF=gi:5453689 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1 NM_006145 DnaJ (Hsp40) homolog, subfamily B, member 1 DNAJB1 3337 NM_006145 /// XM_006722733 /// XM_006722734 /// XM_006722735 /// XM_006722736 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 200667_at BF448062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448062 /FEA=EST /DB_XREF=gi:11513123 /DB_XREF=est:7q97h09.x1 /CLONE=IMAGE:3706600 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 BF448062 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200668_s_at BC003395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003395.1 /DEF=Homo sapiens, ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45), clone MGC:5416, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:13097281 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 BC003395 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200669_s_at NM_003340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003340.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) (UBE2D3), mRNA. /FEA=mRNA /GEN=UBE2D3 /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:4507776 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 NM_003340 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200670_at NM_005080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005080.1 /DEF=Homo sapiens X-box binding protein 1 (XBP1), mRNA. /FEA=mRNA /GEN=XBP1 /PROD=X-box binding protein 1 /DB_XREF=gi:4827057 /UG=Hs.149923 X-box binding protein 1 /FL=gb:BC000938.1 gb:M31627.1 gb:NM_005080.1 NM_005080 X-box binding protein 1 XBP1 7494 NM_001079539 /// NM_005080 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060096 // serotonin secretion, neurotransmission // inferred from electronic annotation /// 0060691 // epithelial cell maturation involved in salivary gland development // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200671_s_at N92501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92501 /FEA=EST /DB_XREF=gi:1264810 /DB_XREF=est:zb28a07.s1 /CLONE=IMAGE:304884 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1 N92501 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200672_x_at NM_003128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003128.1 /DEF=Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), mRNA. /FEA=mRNA /GEN=SPTBN1 /PROD=spectrin, beta, non-erythrocytic 1 /DB_XREF=gi:4507194 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1 NM_003128 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200673_at NM_014713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014713.2 /DEF=Homo sapiens lysosomal-associated protein transmembrane 4 alpha (MBNT), mRNA. /FEA=mRNA /GEN=MBNT /PROD=lysosomal-associated protein transmembrane 4alpha /DB_XREF=gi:13518239 /UG=Hs.111894 lysosomal-associated protein transmembrane 4 alpha /FL=gb:BC000421.1 gb:BC003158.1 gb:NM_014713.2 gb:D14696.1 NM_014713 lysosomal protein transmembrane 4 alpha LAPTM4A 9741 NM_014713 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200674_s_at NM_000994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000994.1 /DEF=Homo sapiens ribosomal protein L32 (RPL32), mRNA. /FEA=mRNA /GEN=RPL32 /PROD=ribosomal protein L32 /DB_XREF=gi:4506634 /UG=Hs.169793 ribosomal protein L32 /FL=gb:NM_000994.1 NM_000994 ribosomal protein L32 RPL32 6161 NM_000994 /// NM_001007073 /// NM_001007074 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200675_at NM_004356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004356.1 /DEF=Homo sapiens CD81 antigen (target of antiproliferative antibody 1) (CD81), mRNA. /FEA=mRNA /GEN=CD81 /PROD=CD81 antigen (target of antiproliferativeantibody 1) /DB_XREF=gi:4757943 /UG=Hs.54457 CD81 antigen (target of antiproliferative antibody 1) /FL=gb:BC002978.1 gb:M33680.1 gb:NM_004356.1 NM_004356 CD81 molecule CD81 975 NM_004356 /// XM_005253260 0000187 // activation of MAPK activity // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0008104 // protein localization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043128 // positive regulation of 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0046718 // viral entry into host cell // traceable author statement /// 0046813 // receptor-mediated virion attachment to host cell // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 200676_s_at NM_003347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003347.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), mRNA. /FEA=mRNA /GEN=UBE2L3 /PROD=ubiquitin-conjugating enzyme E2L 3 /DB_XREF=gi:4507788 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 NM_003347 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200677_at NM_004339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004339.2 /DEF=Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA. /FEA=mRNA /GEN=PTTG1IP /PROD=pituitary tumor-transforming protein1-interacting protein precursor /DB_XREF=gi:11038670 /UG=Hs.111126 pituitary tumor-transforming 1 interacting protein /FL=gb:NM_004339.2 gb:BC000415.1 gb:AF149785.1 NM_004339 pituitary tumor-transforming 1 interacting protein PTTG1IP 754 NM_001286822 /// NM_004339 /// NR_104597 0006606 // protein import into nucleus // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 200678_x_at NM_002087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002087.1 /DEF=Homo sapiens granulin (GRN), mRNA. /FEA=mRNA /GEN=GRN /PROD=granulin /DB_XREF=gi:4504150 /UG=Hs.180577 granulin /FL=gb:M75161.1 gb:AF055008.1 gb:NM_002087.1 NM_002087 granulin GRN 2896 NM_001012479 /// NM_002087 /// XM_005257253 0001835 // blastocyst hatching // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200679_x_at BE311760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE311760 /FEA=EST /DB_XREF=gi:9148272 /DB_XREF=est:601143587F1 /CLONE=IMAGE:3507284 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1 BE311760 high mobility group box 1 HMGB1 3146 NM_002128 /// XM_005266363 /// XM_005266365 /// XM_005266368 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001773 // myeloid dendritic cell activation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from expression pattern /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 2000426 // negative regulation of apoptotic cell clearance // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0042056 // chemoattractant activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 200680_x_at NM_002128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002128.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 1 (HMG1), mRNA. /FEA=mRNA /GEN=HMG1 /PROD=high-mobility group (nonhistone chromosomal)protein 1 /DB_XREF=gi:4504424 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1 NM_002128 high mobility group box 1 HMGB1 3146 NM_002128 /// XM_005266363 /// XM_005266365 /// XM_005266368 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001773 // myeloid dendritic cell activation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from expression pattern /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 2000426 // negative regulation of apoptotic cell clearance // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0042056 // chemoattractant activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 200681_at NM_006708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006708.1 /DEF=Homo sapiens glyoxalase I (GLO1), mRNA. /FEA=mRNA /GEN=GLO1 /PROD=glyoxalase I /DB_XREF=gi:5729841 /UG=Hs.75207 glyoxalase I /FL=gb:BC001741.1 gb:L07837.1 gb:NM_006708.1 NM_006708 glyoxalase I GLO1 2739 NM_006708 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009438 // methylglyoxal metabolic process // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004462 // lactoylglutathione lyase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200682_s_at BG531983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG531983 /FEA=EST /DB_XREF=gi:13523521 /DB_XREF=est:602561007F1 /CLONE=IMAGE:4699176 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BG531983 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200683_s_at BE964689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964689 /FEA=EST /DB_XREF=gi:11768267 /DB_XREF=est:601658226R1 /CLONE=IMAGE:3885630 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BE964689 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200684_s_at AI819709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI819709 /FEA=EST /DB_XREF=gi:5438788 /DB_XREF=est:wj77c07.x1 /CLONE=IMAGE:2408844 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 AI819709 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200685_at AU146237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146237 /FEA=EST /DB_XREF=gi:11007758 /DB_XREF=est:AU146237 /CLONE=HEMBA1007233 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1 AU146237 serine/arginine-rich splicing factor 11 SRSF11 9295 NM_001190987 /// NM_004768 /// XM_005271338 /// XM_005271339 /// XM_006711037 /// XM_006711038 /// XM_006711039 /// XM_006711040 /// XM_006711041 /// XR_426640 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200686_s_at NM_004768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004768.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 11 (SFRS11), mRNA. /FEA=mRNA /GEN=SFRS11 /PROD=splicing factor, arginineserine-rich 11 /DB_XREF=gi:4759099 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1 NM_004768 serine/arginine-rich splicing factor 11 SRSF11 9295 NM_001190987 /// NM_004768 /// XM_005271338 /// XM_005271339 /// XM_006711037 /// XM_006711038 /// XM_006711039 /// XM_006711040 /// XM_006711041 /// XR_426640 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200687_s_at NM_012426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012426.1 /DEF=Homo sapiens splicing factor 3b, subunit 3, 130kD (SF3B3), mRNA. /FEA=mRNA /GEN=SF3B3 /PROD=splicing factor 3b, subunit 3, 130kD /DB_XREF=gi:11034822 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1 NM_012426 splicing factor 3b, subunit 3, 130kDa SF3B3 23450 NM_012426 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200688_at D13642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13642.1 /DEF=Human mRNA for KIAA0017 gene, complete cds. /FEA=mRNA /GEN=KIAA0017 /DB_XREF=gi:285998 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1 D13642 splicing factor 3b, subunit 3, 130kDa SF3B3 23450 NM_012426 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200689_x_at NM_001404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001404.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA. /FEA=mRNA /GEN=EEF1G /PROD=eukaryotic translation elongation factor 1gamma /DB_XREF=gi:4503480 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma /FL=gb:BC000384.1 gb:BC004189.1 gb:BC004215.1 gb:NM_001404.1 NM_001404 eukaryotic translation elongation factor 1 gamma /// microRNA 3654 EEF1G /// MIR3654 1937 /// 100500804 NM_001404 /// NR_037427 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200690_at AA927701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA927701 /FEA=EST /DB_XREF=gi:3076521 /DB_XREF=est:om72d09.s1 /CLONE=IMAGE:1552721 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 AA927701 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200691_s_at BC000478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000478.1 /DEF=Homo sapiens, heat shock 70kD protein 9B (mortalin-2), clone MGC:8684, mRNA, complete cds. /FEA=mRNA /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:12653414 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 BC000478 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200692_s_at NM_004134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004134.1 /DEF=Homo sapiens heat shock 70kD protein 9B (mortalin-2) (HSPA9B), mRNA. /FEA=mRNA /GEN=HSPA9B /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:4758569 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 NM_004134 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200693_at NM_006826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006826.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ), mRNA. /FEA=mRNA /GEN=YWHAQ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, theta polypeptide /DB_XREF=gi:5803226 /UG=Hs.74405 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide /FL=gb:NM_006826.1 NM_006826 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta YWHAQ 10971 NM_006826 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200694_s_at NM_020414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020414.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 (DDX24), mRNA. /FEA=mRNA /GEN=DDX24 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /DB_XREF=gi:13787212 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1 NM_020414 DEAD (Asp-Glu-Ala-Asp) box helicase 24 DDX24 57062 NM_020414 0003351 // epithelial cilium movement // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200695_at NM_014225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014225.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA. /FEA=mRNA /GEN=PPP2R1A /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit A (PR 65), alpha isoform /DB_XREF=gi:7657474 /UG=Hs.173902 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform /FL=gb:J02902.1 gb:NM_014225.1 NM_014225 protein phosphatase 2, regulatory subunit A, alpha PPP2R1A 5518 NM_014225 /// NR_033500 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000188 // inactivation of MAPK activity // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006470 // protein dephosphorylation // traceable author statement /// 0006672 // ceramide metabolic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007059 // chromosome segregation // inferred from direct assay /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0008380 // RNA splicing // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019932 // second-messenger-mediated signaling // non-traceable author statement /// 0030111 // regulation of Wnt signaling pathway // non-traceable author statement /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0070262 // peptidyl-serine dephosphorylation // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // non-traceable author statement /// 0016020 // membrane // non-traceable author statement 0003823 // antigen binding // inferred from physical interaction /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200696_s_at NM_000177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000177.1 /DEF=Homo sapiens gelsolin (amyloidosis, Finnish type) (GSN), mRNA. /FEA=mRNA /GEN=GSN /PROD=gelsolin (amyloidosis, Finnish type) /DB_XREF=gi:4504164 /UG=Hs.290070 gelsolin (amyloidosis, Finnish type) /FL=gb:NM_000177.1 NM_000177 gelsolin GSN 2934 NM_000177 /// NM_001127662 /// NM_001127663 /// NM_001127664 /// NM_001127665 /// NM_001127666 /// NM_001127667 /// NM_001258029 /// NM_001258030 /// NM_198252 /// XM_005251940 /// XM_005251943 /// XM_005251944 /// XM_005251945 /// XM_006717075 /// XM_006717076 /// XM_006717077 /// XM_006717078 /// XM_006717079 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051014 // actin filament severing // inferred from direct assay /// 0051014 // actin filament severing // inferred from sequence or structural similarity /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200697_at NM_000188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000188.1 /DEF=Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=HK1 /PROD=hexokinase 1 /DB_XREF=gi:4504390 /UG=Hs.118625 hexokinase 1 /FL=gb:M75126.1 gb:NM_000188.1 NM_000188 hexokinase 1 HK1 3098 NM_000188 /// NM_033496 /// NM_033497 /// NM_033498 /// NM_033500 /// XM_005269735 /// XM_005269736 /// XM_005269737 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006096 // glycolytic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded 200698_at AL542253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL542253 /FEA=EST /DB_XREF=gi:12874115 /DB_XREF=est:AL542253 /CLONE=CS0DE008YC08 (3 prime) /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 AL542253 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200699_at BE962456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962456 /FEA=EST /DB_XREF=gi:11765376 /DB_XREF=est:601655751R1 /CLONE=IMAGE:3846156 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 BE962456 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200700_s_at NM_006854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006854.2 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2), mRNA. /FEA=mRNA /GEN=KDELR2 /PROD=KDEL receptor 2 /DB_XREF=gi:8051609 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 NM_006854 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200701_at NM_006432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006432.1 /DEF=Homo sapiens epididymal secretory protein (19.5kD) (HE1), mRNA. /FEA=mRNA /GEN=HE1 /PROD=epididymal secretory protein (19.5kD) /DB_XREF=gi:5453677 /UG=Hs.119529 epididymal secretory protein (19.5kD) /FL=gb:BC002532.1 gb:NM_006432.1 NM_006432 Niemann-Pick disease, type C2 NPC2 10577 NM_006432 /// XM_006720004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0015914 // phospholipid transport // traceable author statement /// 0019747 // regulation of isoprenoid metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from direct assay /// 0032366 // intracellular sterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from genetic interaction /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0046836 // glycolipid transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 200702_s_at BG421209 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG421209 /FEA=EST /DB_XREF=gi:13327715 /DB_XREF=est:602451696F1 /CLONE=IMAGE:4590215 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1 BG421209 DEAD (Asp-Glu-Ala-Asp) box helicase 24 DDX24 57062 NM_020414 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200703_at NM_003746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003746.1 /DEF=Homo sapiens dynein, cytoplasmic, light polypeptide (PIN), mRNA. /FEA=mRNA /GEN=PIN /PROD=dynein, cytoplasmic, light polypeptide /DB_XREF=gi:4505812 /UG=Hs.5120 dynein, cytoplasmic, light polypeptide /FL=gb:U32944.1 gb:NM_003746.1 NM_003746 dynein, light chain, LC8-type 1 DYNLL1 8655 NM_001037494 /// NM_001037495 /// NM_003746 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 200704_at AB034747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB034747.1 /DEF=Homo sapiens SIMPLE mRNA for small integral membrane protein of lysosomelate endosome, complete cds. /FEA=mRNA /GEN=SIMPLE /PROD=small integral membrane protein of lysosomelateendosome /DB_XREF=gi:12862475 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1 AB034747 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 /// XM_006720982 /// XM_006720983 /// XM_006720984 /// XM_006720985 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200705_s_at NM_001959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001959.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 beta 2 (EEF1B2), mRNA. /FEA=mRNA /GEN=EEF1B2 /PROD=eukaryotic translation elongation factor 1 beta2 /DB_XREF=gi:4503476 /UG=Hs.275959 eukaryotic translation elongation factor 1 beta 2 /FL=gb:BC004931.1 gb:NM_001959.1 NM_001959 eukaryotic translation elongation factor 1 beta 2 /// small nucleolar RNA, H/ACA box 41 EEF1B2 /// SNORA41 1933 /// 619569 NM_001037663 /// NM_001959 /// NM_021121 /// NR_002590 0006412 // translation // traceable author statement /// 0006414 // translational elongation // non-traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // non-traceable author statement 0003746 // translation elongation factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200706_s_at NM_004862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004862.1 /DEF=Homo sapiens LPS-induced TNF-alpha factor (PIG7), mRNA. /FEA=mRNA /GEN=PIG7 /PROD=LPS-induced TNF-alpha factor /DB_XREF=gi:4758913 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1 NM_004862 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 /// XM_006720982 /// XM_006720983 /// XM_006720984 /// XM_006720985 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200707_at NM_002743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002743.1 /DEF=Homo sapiens protein kinase C substrate 80K-H (PRKCSH), mRNA. /FEA=mRNA /GEN=PRKCSH /PROD=protein kinase C substrate 80K-H /DB_XREF=gi:4506076 /UG=Hs.1432 protein kinase C substrate 80K-H /FL=gb:J03075.1 gb:NM_002743.1 gb:AF144075.1 NM_002743 protein kinase C substrate 80K-H PRKCSH 5589 NM_001001329 /// NM_001289102 /// NM_001289103 /// NM_001289104 /// NM_002743 /// XM_006722795 /// XM_006722796 /// XM_006722797 /// XM_006722798 /// XR_430144 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006491 // N-glycan processing // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 200708_at NM_002080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002080.1 /DEF=Homo sapiens glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=GOT2 /PROD=aspartate aminotransferase 2 precursor /DB_XREF=gi:4504068 /UG=Hs.170197 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) /FL=gb:BC000525.1 gb:M22632.1 gb:NM_002080.1 NM_002080 glutamic-oxaloacetic transaminase 2, mitochondrial GOT2 2806 NM_001286220 /// NM_002080 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006531 // aspartate metabolic process // inferred from sequence or structural similarity /// 0006532 // aspartate biosynthetic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from expression pattern /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0019550 // glutamate catabolic process to aspartate // inferred from electronic annotation /// 0019551 // glutamate catabolic process to 2-oxoglutarate // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0097052 // L-kynurenine metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // not recorded /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from direct assay /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from sequence or structural similarity /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016212 // kynurenine-oxoglutarate transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0080130 // L-phenylalanine:2-oxoglutarate aminotransferase activity // inferred from electronic annotation 200709_at NM_000801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000801.1 /DEF=Homo sapiens FK506-binding protein 1A (12kD) (FKBP1A), mRNA. /FEA=mRNA /GEN=FKBP1A /PROD=FK506-binding protein 1A (12kD) /DB_XREF=gi:4503724 /UG=Hs.752 FK506-binding protein 1A (12kD) /FL=gb:BC001925.1 gb:M34539.1 gb:NM_000801.1 NM_000801 FK506 binding protein 1A, 12kDa /// uncharacterized LOC101929368 FKBP1A /// LOC101929368 2280 /// 101929368 NM_000801 /// NM_001199786 /// NM_054014 /// XR_245428 /// XR_247917 /// XR_253167 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0018208 // peptidyl-proline modification // /// 0022417 // protein maturation by protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from genetic interaction /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded /// 0070588 // calcium ion transmembrane transport // non-traceable author statement /// 1902991 // regulation of amyloid precursor protein catabolic process // inferred from genetic interaction /// 1990000 // amyloid fibril formation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030424 // axon // /// 0033017 // sarcoplasmic reticulum membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005527 // macrolide binding // non-traceable author statement /// 0005528 // FK506 binding // inferred from direct assay /// 0005528 // FK506 binding // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 200710_at NM_000018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000018.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, very long chain (ACADVL), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADVL /PROD=acyl-Coenzyme A dehydrogenase, very long chainprecursor /DB_XREF=gi:4557234 /UG=Hs.82208 acyl-Coenzyme A dehydrogenase, very long chain /FL=gb:D43682.1 gb:BC000399.1 gb:NM_000018.1 NM_000018 acyl-CoA dehydrogenase, very long chain ACADVL 37 NM_000018 /// NM_001033859 /// NM_001270447 /// NM_001270448 /// XM_006721516 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015980 // energy derivation by oxidation of organic compounds // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004466 // long-chain-acyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 200711_s_at NM_003197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003197.2 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 1-like (TCEB1L), mRNA. /FEA=mRNA /GEN=TCEB1L /PROD=transcription elongation factor B polypeptide1-like /DB_XREF=gi:6006030 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 NM_003197 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200712_s_at AI633566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633566 /FEA=EST /DB_XREF=gi:4684896 /DB_XREF=est:th68f09.x1 /CLONE=IMAGE:2123849 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1 AI633566 microtubule-associated protein, RP/EB family, member 1 MAPRE1 22919 NM_012325 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031113 // regulation of microtubule polymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 200713_s_at NM_012325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012325.1 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 1 (MAPRE1), mRNA. /FEA=mRNA /GEN=MAPRE1 /PROD=microtubule-associated protein, RPEB family,member 1 /DB_XREF=gi:6912493 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1 NM_012325 microtubule-associated protein, RP/EB family, member 1 MAPRE1 22919 NM_012325 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031113 // regulation of microtubule polymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 200714_x_at NM_006812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006812.1 /DEF=Homo sapiens amplified in osteosarcoma (OS-9), mRNA. /FEA=mRNA /GEN=OS-9 /PROD=amplified in osteosarcoma /DB_XREF=gi:5803108 /UG=Hs.76228 amplified in osteosarcoma /FL=gb:U41635.1 gb:AB002806.1 gb:NM_006812.1 NM_006812 osteosarcoma amplified 9, endoplasmic reticulum lectin OS9 10956 NM_001017956 /// NM_001017957 /// NM_001017958 /// NM_001261420 /// NM_001261421 /// NM_001261422 /// NM_001261423 /// NM_006812 /// XM_005268581 /// XM_006719200 /// XM_006719201 0006605 // protein targeting // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000836 // Hrd1p ubiquitin ligase complex // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200715_x_at BC000514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000514.1 /DEF=Homo sapiens, ribosomal protein L13a, clone MGC:8547, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L13a /DB_XREF=gi:12653484 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1 BC000514 ribosomal protein L13a /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A RPL13A /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_073024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200716_x_at NM_012423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012423.1 /DEF=Homo sapiens ribosomal protein L13a (RPL13A), mRNA. /FEA=mRNA /GEN=RPL13A /PROD=ribosomal protein L13a /DB_XREF=gi:6912633 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1 NM_012423 ribosomal protein L13a /// ribosomal protein L13a pseudogene 5 /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A RPL13A /// RPL13AP5 /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 /// 728658 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_026712 /// NR_073024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200717_x_at NM_000971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000971.1 /DEF=Homo sapiens ribosomal protein L7 (RPL7), mRNA. /FEA=mRNA /GEN=RPL7 /PROD=ribosomal protein L7 /DB_XREF=gi:4506658 /UG=Hs.153 ribosomal protein L7 /FL=gb:L16558.1 gb:NM_000971.1 NM_000971 ribosomal protein L7 RPL7 6129 NM_000971 /// XM_006716463 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200718_s_at AA927664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA927664 /FEA=EST /DB_XREF=gi:3076484 /DB_XREF=est:om71h10.s1 /CLONE=IMAGE:1552675 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 AA927664 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200719_at BE964043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964043 /FEA=EST /DB_XREF=gi:11767371 /DB_XREF=est:601657616R1 /CLONE=IMAGE:3875955 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 BE964043 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200720_s_at AL532341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL532341 /FEA=EST /DB_XREF=gi:12795834 /DB_XREF=est:AL532341 /CLONE=CS0DM014YJ21 (5 prime) /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2 AL532341 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) ACTR1A 10121 NM_005736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200721_s_at NM_005736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005736.2 /DEF=Homo sapiens ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) (ACTR1A), mRNA. /FEA=mRNA /GEN=ACTR1A /PROD=actin-related protein 1A /DB_XREF=gi:13325058 /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2 NM_005736 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) ACTR1A 10121 NM_005736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200722_s_at BG258784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG258784 /FEA=EST /DB_XREF=gi:12768600 /DB_XREF=est:602378049F1 /CLONE=IMAGE:4508820 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1 BG258784 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003723 // RNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200723_s_at NM_005898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005898.1 /DEF=Homo sapiens membrane component, chromosome 11, surface marker 1 (M11S1), mRNA. /FEA=mRNA /GEN=M11S1 /PROD=membrane component, chromosome 11, surfacemarker 1 /DB_XREF=gi:5174502 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1 NM_005898 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003723 // RNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200724_at BC003358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003358.1 /DEF=Homo sapiens, ribosomal protein L10, clone MGC:5189, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L10 /DB_XREF=gi:13097176 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1 BC003358 ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70 RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200725_x_at NM_006013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006013.1 /DEF=Homo sapiens ribosomal protein L10 (RPL10), mRNA. /FEA=mRNA /GEN=RPL10 /PROD=ribosomal protein L10 /DB_XREF=gi:5174430 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1 NM_006013 ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70 RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200726_at NM_002710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002710.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, gamma isoform (PPP1CC), mRNA. /FEA=mRNA /GEN=PPP1CC /PROD=protein phosphatase 1, catalytic subunit, gammaisoform /DB_XREF=gi:4506006 /UG=Hs.79081 protein phosphatase 1, catalytic subunit, gamma isoform /FL=gb:NM_002710.1 NM_002710 protein phosphatase 1, catalytic subunit, gamma isozyme PPP1CC 5501 NM_001244974 /// NM_002710 /// XM_006719469 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200727_s_at AA699583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA699583 /FEA=EST /DB_XREF=gi:2703730 /DB_XREF=est:zi42g07.s1 /CLONE=IMAGE:433500 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 AA699583 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200728_at BE566290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE566290 /FEA=EST /DB_XREF=gi:9810010 /DB_XREF=est:601339864F1 /CLONE=IMAGE:3682406 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 BE566290 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200729_s_at NM_005722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005722.1 /DEF=Homo sapiens ARP2 (actin-related protein 2, yeast) homolog (ACTR2), mRNA. /FEA=mRNA /GEN=ACTR2 /PROD=ARP2 (actin-related protein 2, yeast) homolog /DB_XREF=gi:5031570 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 NM_005722 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200730_s_at BF576710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF576710 /FEA=EST /DB_XREF=gi:11650422 /DB_XREF=est:602135085F1 /CLONE=IMAGE:4290141 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 BF576710 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200731_s_at AW165960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW165960 /FEA=EST /DB_XREF=gi:6397485 /DB_XREF=est:xf43a12.x1 /CLONE=IMAGE:2620798 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 AW165960 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200732_s_at AL578310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL578310 /FEA=EST /DB_XREF=gi:12942259 /DB_XREF=est:AL578310 /CLONE=CS0DK010YM06 (3 prime) /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 AL578310 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200733_s_at U48296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U48296.1 /DEF=Homo sapiens protein tyrosine phosphatase PTPCAAX1 (hPTPCAAX1) mRNA, complete cds. /FEA=mRNA /GEN=hPTPCAAX1 /PROD=protein tyrosine phosphatase PTPCAAX1 /DB_XREF=gi:1777754 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 U48296 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200734_s_at BG341906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG341906 /FEA=EST /DB_XREF=gi:13148344 /DB_XREF=est:602463246F1 /CLONE=IMAGE:4576258 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1 BG341906 ADP-ribosylation factor 3 ARF3 377 NM_001659 /// XM_005268856 /// XM_006719391 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 200735_x_at NM_005594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005594.1 /DEF=Homo sapiens nascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA. /FEA=mRNA /GEN=NACA /PROD=nascent-polypeptide-associated complex alphapolypeptide /DB_XREF=gi:5031930 /UG=Hs.32916 nascent-polypeptide-associated complex alpha polypeptide /FL=gb:AF054187.1 gb:NM_005594.1 NM_005594 nascent polypeptide-associated complex alpha subunit NACA 4666 NM_001113201 /// NM_001113202 /// NM_001113203 /// NM_005594 /// NR_045277 /// XM_006719412 /// XM_006719413 /// XM_006719414 /// XM_006719415 /// XM_006719416 /// XM_006719417 /// XM_006719418 /// XM_006719419 /// XM_006719420 /// XM_006719421 0003231 // cardiac ventricle development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 1901227 // negative regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 1901228 // positive regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005854 // nascent polypeptide-associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from sequence or structural similarity 200736_s_at NM_000581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000581.1 /DEF=Homo sapiens glutathione peroxidase 1 (GPX1), mRNA. /FEA=mRNA /GEN=GPX1 /PROD=glutathione peroxidase 1 /DB_XREF=gi:10834975 /UG=Hs.76686 glutathione peroxidase 1 /FL=gb:NM_000581.1 gb:BC000742.1 gb:M21304.1 NM_000581 glutathione peroxidase 1 GPX1 2876 NM_000581 /// NM_201397 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009609 // response to symbiotic bacterium // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from mutant phenotype /// 0035094 // response to nicotine // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from mutant phenotype /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051702 // interaction with symbiont // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from electronic annotation /// 0047066 // phospholipid-hydroperoxide glutathione peroxidase activity // inferred from electronic annotation 200737_at NM_000291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1 NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200738_s_at NM_000291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1 NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200739_s_at BG338532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG338532 /FEA=EST /DB_XREF=gi:13144970 /DB_XREF=est:602436260F1 /CLONE=IMAGE:4554278 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1 BG338532 small ubiquitin-like modifier 3 SUMO3 6612 NM_001286416 /// NM_006936 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019789 // SUMO ligase activity // inferred from electronic annotation 200740_s_at NM_006936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006936.1 /DEF=Homo sapiens SMT3 (suppressor of mif two 3, yeast) homolog 1 (SMT3H1), mRNA. /FEA=mRNA /GEN=SMT3H1 /PROD=SMT3 (suppressor of mif two 3, yeast) homolog 1 /DB_XREF=gi:5902095 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1 NM_006936 small ubiquitin-like modifier 3 SUMO3 6612 NM_001286416 /// NM_006936 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019789 // SUMO ligase activity // inferred from electronic annotation 200741_s_at NM_001030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001030.1 /DEF=Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA. /FEA=mRNA /GEN=RPS27 /PROD=ribosomal protein S27 (metallopanstimulin 1) /DB_XREF=gi:4506710 /UG=Hs.195453 ribosomal protein S27 (metallopanstimulin 1) /FL=gb:U57847.1 gb:L19739.1 gb:NM_001030.1 NM_001030 ribosomal protein S27 RPS27 6232 NM_001030 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200742_s_at BG231932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG231932 /FEA=EST /DB_XREF=gi:12727071 /DB_XREF=est:naf34b12.x1 /CLONE=IMAGE:4142926 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2 BG231932 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 200743_s_at NM_000391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000391.2 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) (CLN2), mRNA. /FEA=mRNA /GEN=CLN2 /PROD=ceroid-lipofuscinosis, neuronal 2, lateinfantile (Jansky-Bielschowsky disease) /DB_XREF=gi:5597012 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2 NM_000391 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 200744_s_at AI741124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741124 /FEA=EST /DB_XREF=gi:5109412 /DB_XREF=est:wg19c04.x1 /CLONE=IMAGE:2365542 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 AI741124 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200745_s_at AF070603 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070603.1 /DEF=Homo sapiens clone 24584 beta-subunit signal transducing proteins GSGI mRNA, partial cds. /FEA=mRNA /PROD=beta-subunit signal transducing proteins GSGI /DB_XREF=gi:3387983 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 AF070603 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200746_s_at NM_002074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002074.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1), mRNA. /FEA=mRNA /GEN=GNB1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 1 /DB_XREF=gi:11321584 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 NM_002074 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200747_s_at NM_006185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006185.1 /DEF=Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), mRNA. /FEA=mRNA /GEN=NUMA1 /PROD=nuclear mitotic apparatus protein 1 /DB_XREF=gi:5453819 /UG=Hs.301512 nuclear mitotic apparatus protein 1 /FL=gb:NM_006185.1 NM_006185 nuclear mitotic apparatus protein 1 NUMA1 4926 NM_001286561 /// NM_006185 /// NR_104476 /// XM_006718562 /// XM_006718563 /// XM_006718564 /// XM_006718565 /// XM_006718566 /// XM_006718567 /// XM_006718568 /// XM_006718569 /// XM_006718570 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006997 // nucleus organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation 200748_s_at NM_002032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002032.1 /DEF=Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA. /FEA=mRNA /GEN=FTH1 /PROD=ferritin, heavy polypeptide 1 /DB_XREF=gi:4503794 /UG=Hs.62954 ferritin, heavy polypeptide 1 /FL=gb:BC000857.1 gb:BC001399.1 gb:M11146.1 gb:M12937.1 gb:M97164.1 gb:NM_002032.1 gb:L20941.1 NM_002032 ferritin, heavy polypeptide 1 FTH1 2495 NM_002032 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006880 // intracellular sequestering of iron ion // inferred from direct assay /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008043 // intracellular ferritin complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 200749_at BF112006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF112006 /FEA=EST /DB_XREF=gi:10941619 /DB_XREF=est:7l37e05.x1 /CLONE=IMAGE:3523665 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2 BF112006 RAN, member RAS oncogene family RAN 5901 NM_006325 /// XM_005253592 0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement 200750_s_at AF054183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054183.1 /DEF=Homo sapiens GTP binding protein mRNA, complete cds. /FEA=mRNA /PROD=GTP binding protein /DB_XREF=gi:4092053 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2 AF054183 RAN, member RAS oncogene family RAN 5901 NM_006325 /// XM_005253592 0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement 200751_s_at BE898861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE898861 /FEA=EST /DB_XREF=gi:10365758 /DB_XREF=est:601682157F1 /CLONE=IMAGE:3952046 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1 BE898861 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200752_s_at NM_005186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005186.2 /DEF=Homo sapiens calpain 1, (muI) large subunit (CAPN1), mRNA. /FEA=mRNA /GEN=CAPN1 /PROD=calpain 1, large subunit /DB_XREF=gi:12408655 /UG=Hs.2575 calpain 1, (muI) large subunit /FL=gb:NM_005186.2 NM_005186 calpain 1, (mu/I) large subunit CAPN1 823 NM_001198868 /// NM_001198869 /// NM_005186 /// NR_040008 /// XM_006718698 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032801 // receptor catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200753_x_at BE866585 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE866585 /FEA=EST /DB_XREF=gi:10315361 /DB_XREF=est:601678773F1 /CLONE=IMAGE:3961243 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1 BE866585 microRNA 636 /// serine/arginine-rich splicing factor 2 MIR636 /// SRSF2 6427 /// 693221 NM_001195427 /// NM_003016 /// NR_030366 /// NR_036608 /// XR_429913 /// XR_429914 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200754_x_at NM_003016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003016.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 2 (SFRS2), mRNA. /FEA=mRNA /GEN=SFRS2 /PROD=splicing factor, arginineserine-rich 2 /DB_XREF=gi:4506898 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1 NM_003016 microRNA 636 /// serine/arginine-rich splicing factor 2 MIR636 /// SRSF2 6427 /// 693221 NM_001195427 /// NM_003016 /// NR_030366 /// NR_036608 /// XR_429913 /// XR_429914 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200755_s_at BF939365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939365 /FEA=EST /DB_XREF=gi:12356685 /DB_XREF=est:nad87h04.x1 /CLONE=IMAGE:3410551 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 BF939365 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200756_x_at U67280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U67280.1 /DEF=Homo sapiens calumenin mRNA, complete cds. /FEA=mRNA /PROD=calumenin /DB_XREF=gi:2809323 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 U67280 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200757_s_at NM_001219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001219.2 /DEF=Homo sapiens calumenin (CALU), mRNA. /FEA=mRNA /GEN=CALU /PROD=calumenin precursor /DB_XREF=gi:6005991 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 NM_001219 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200758_s_at AI361227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI361227 /FEA=EST /DB_XREF=gi:4112848 /DB_XREF=est:qy12a07.x1 /CLONE=IMAGE:2011764 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1 AI361227 nuclear factor, erythroid 2-like 1 NFE2L1 4779 NM_003204 /// XM_005257410 /// XM_005257411 /// XM_005257412 /// XM_005257413 /// XM_005257415 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200759_x_at NM_003204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003204.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 1 (NFE2L1), mRNA. /FEA=mRNA /GEN=NFE2L1 /PROD=transcription factor 11 (basic leucine zippertype) /DB_XREF=gi:4505378 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1 NM_003204 nuclear factor, erythroid 2-like 1 NFE2L1 4779 NM_003204 /// XM_005257410 /// XM_005257411 /// XM_005257412 /// XM_005257413 /// XM_005257415 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200760_s_at N92494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92494 /FEA=EST /DB_XREF=gi:1264803 /DB_XREF=est:zb12h11.s1 /CLONE=IMAGE:301893 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2 N92494 ADP-ribosylation factor-like 6 interacting protein 5 ARL6IP5 10550 NM_006407 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051051 // negative regulation of transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 200761_s_at NM_006407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006407.2 /DEF=Homo sapiens vitamin A responsive; cytoskeleton related (JWA), mRNA. /FEA=mRNA /GEN=JWA /PROD=vitamin A responsive; cytoskeleton related /DB_XREF=gi:7669496 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2 NM_006407 ADP-ribosylation factor-like 6 interacting protein 5 ARL6IP5 10550 NM_006407 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051051 // negative regulation of transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 200762_at NM_001386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001386.1 /DEF=Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), mRNA. /FEA=mRNA /GEN=DPYSL2 /PROD=dihydropyrimidinase-like 2 /DB_XREF=gi:4503376 /UG=Hs.173381 dihydropyrimidinase-like 2 /FL=gb:U17279.1 gb:D78013.1 gb:U97105.1 gb:NM_001386.1 NM_001386 dihydropyrimidinase-like 2 DPYSL2 1808 NM_001197293 /// NM_001244604 /// NM_001386 0001975 // response to amphetamine // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004157 // dihydropyrimidinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 200763_s_at NM_001003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001003.1 /DEF=Homo sapiens ribosomal protein, large, P1 (RPLP1), mRNA. /FEA=mRNA /GEN=RPLP1 /PROD=ribosomal protein, large, P1 /DB_XREF=gi:4506668 /UG=Hs.177592 ribosomal protein, large, P1 /FL=gb:BC003369.1 gb:M17886.1 gb:NM_001003.1 NM_001003 ribosomal protein, large, P1 RPLP1 6176 NM_001003 /// NM_213725 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200764_s_at AI826881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI826881 /FEA=EST /DB_XREF=gi:5447552 /DB_XREF=est:wk75f03.x1 /CLONE=IMAGE:2421245 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1 AI826881 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 200765_x_at NM_001903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001903.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha 1 (102kD) (CTNNA1), mRNA. /FEA=mRNA /GEN=CTNNA1 /PROD=catenin (cadherin-associated protein), alpha 1(102kD) /DB_XREF=gi:4503126 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1 NM_001903 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 200766_at NM_001909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001909.1 /DEF=Homo sapiens cathepsin D (lysosomal aspartyl protease) (CTSD), mRNA. /FEA=mRNA /GEN=CTSD /PROD=cathepsin D (lysosomal aspartyl protease) /DB_XREF=gi:4503142 /UG=Hs.79572 cathepsin D (lysosomal aspartyl protease) /FL=gb:M11233.1 gb:NM_001909.1 NM_001909 cathepsin D CTSD 1509 NM_001909 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200767_s_at NM_014612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014612.1 /DEF=Homo sapiens C9orf10 protein (C9orf10), mRNA. /FEA=mRNA /GEN=C9orf10 /PROD=C9orf10 protein /DB_XREF=gi:8922113 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1 NM_014612 family with sequence similarity 120A FAM120A 23196 NM_001286722 /// NM_001286723 /// NM_001286724 /// NM_014612 /// XM_005251842 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200768_s_at BC001686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001686.1 /DEF=Homo sapiens, methionine adenosyltransferase II, alpha, clone MGC:2907, mRNA, complete cds. /FEA=mRNA /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:12804546 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1 BC001686 methionine adenosyltransferase II, alpha MAT2A 4144 NM_005911 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from direct assay /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0048269 // methionine adenosyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200769_s_at NM_005911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005911.1 /DEF=Homo sapiens methionine adenosyltransferase II, alpha (MAT2A), mRNA. /FEA=mRNA /GEN=MAT2A /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:5174528 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1 NM_005911 methionine adenosyltransferase II, alpha MAT2A 4144 NM_005911 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from direct assay /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0048269 // methionine adenosyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200770_s_at J03202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03202.1 /DEF=Human laminin B2 chain mRNA, complete cds. /FEA=mRNA /GEN=LAMB2 /DB_XREF=gi:186916 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2 J03202 laminin, gamma 1 (formerly LAMB2) LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // non-traceable author statement /// 0005606 // laminin-1 complex // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043259 // laminin-10 complex // traceable author statement /// 0043260 // laminin-11 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 200771_at NM_002293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002293.2 /DEF=Homo sapiens laminin, gamma 1 (formerly LAMB2) (LAMC1), mRNA. /FEA=mRNA /GEN=LAMC1 /PROD=laminin, gamma 1 precursor /DB_XREF=gi:9845497 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2 NM_002293 laminin, gamma 1 (formerly LAMB2) LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // non-traceable author statement /// 0005606 // laminin-1 complex // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043259 // laminin-10 complex // traceable author statement /// 0043260 // laminin-11 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 200772_x_at BF686442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF686442 /FEA=EST /DB_XREF=gi:11971850 /DB_XREF=est:602143234F1 /CLONE=IMAGE:4304193 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1 BF686442 prothymosin alpha-like /// prothymosin alpha-like /// microRNA 1244-1 /// microRNA 1244-2 /// microRNA 1244-3 /// prothymosin, alpha LOC100506248 /// LOC728026 /// MIR1244-1 /// MIR1244-2 /// MIR1244-3 /// PTMA 5757 /// 728026 /// 100302285 /// 100422872 /// 100422885 /// 100506248 NM_001099285 /// NM_002823 /// NR_036052 /// NR_036262 /// NR_036263 /// XM_001126659 /// XM_003960458 /// XM_005275719 /// XM_005276418 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200773_x_at NM_002823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002823.1 /DEF=Homo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA. /FEA=mRNA /GEN=PTMA /PROD=prothymosin, alpha (gene sequence 28) /DB_XREF=gi:4506276 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1 NM_002823 prothymosin, alpha PTMA 5757 NM_001099285 /// NM_002823 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200774_at BE963765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963765 /FEA=EST /DB_XREF=gi:11767182 /DB_XREF=est:601657412R1 /CLONE=IMAGE:3875738 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1 BE963765 family with sequence similarity 120A FAM120A 23196 NM_001286722 /// NM_001286723 /// NM_001286724 /// NM_014612 /// XM_005251842 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200775_s_at BC000355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000355.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein K, clone MGC:8660, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein K /DB_XREF=gi:12653174 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K /FL=gb:BC000355.1 gb:NM_002140.1 BC000355 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 /// XM_005251960 /// XM_005251961 /// XM_005251963 /// XM_005251964 /// XM_005251965 /// XM_005251966 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200776_s_at AL518328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL518328 /FEA=EST /DB_XREF=gi:12781821 /DB_XREF=est:AL518328 /CLONE=CS0DA009YK18 (3 prime) /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1 AL518328 basic leucine zipper and W2 domains 1 BZW1 9689 NM_001207067 /// NM_001207068 /// NM_001207069 /// NM_014670 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200777_s_at NM_014670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014670.1 /DEF=Homo sapiens KIAA0005 gene product (KIAA0005), mRNA. /FEA=mRNA /GEN=KIAA0005 /PROD=KIAA0005 gene product /DB_XREF=gi:7661849 /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1 NM_014670 basic leucine zipper and W2 domains 1 BZW1 9689 NM_001207067 /// NM_001207068 /// NM_001207069 /// NM_014670 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200778_s_at AI191427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI191427 /FEA=EST /DB_XREF=gi:3742636 /DB_XREF=est:qe48g03.x1 /CLONE=IMAGE:1742260 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1 AI191427 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_001282972 /// NM_001282973 /// NM_004404 /// NM_006155 /// XM_005247011 /// XM_005247012 /// XM_005247013 /// XM_006712546 /// XM_006712547 /// XM_006712548 /// XM_006712549 /// XM_006712550 0002036 // regulation of L-glutamate transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation 200779_at NM_001675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001675.1 /DEF=Homo sapiens activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), mRNA. /FEA=mRNA /GEN=ATF4 /PROD=activating transcription factor 4 /DB_XREF=gi:4502264 /UG=Hs.181243 activating transcription factor 4 (tax-responsive enhancer element B67) /FL=gb:M86842.1 gb:NM_001675.1 NM_001675 activating transcription factor 4 ATF4 468 NM_001675 /// NM_182810 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200780_x_at NM_000516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000516.2 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1), mRNA. /FEA=mRNA /GEN=GNAS1 /PROD=guanine nucleotide binding protein (G protein),alpha stimulating activity polypeptide 1 /DB_XREF=gi:8659565 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 /FL=gb:BC002722.1 gb:AF088185.1 gb:NM_000516.2 NM_000516 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 200781_s_at NM_001019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001019.1 /DEF=Homo sapiens ribosomal protein S15a (RPS15A), mRNA. /FEA=mRNA /GEN=RPS15A /PROD=ribosomal protein S15a /DB_XREF=gi:4506688 /UG=Hs.2953 ribosomal protein S15a /FL=gb:BC001697.1 gb:NM_001019.1 NM_001019 ribosomal protein S15a RPS15A 6210 NM_001019 /// NM_001030009 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200782_at NM_001154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001154.2 /DEF=Homo sapiens annexin A5 (ANXA5), mRNA. /FEA=mRNA /GEN=ANXA5 /PROD=annexin V /DB_XREF=gi:4809273 /UG=Hs.300711 annexin A5 /FL=gb:BC001429.1 gb:BC004993.1 gb:M18366.1 gb:J03745.1 gb:M21731.1 gb:M19384.1 gb:D00172.1 gb:NM_001154.2 NM_001154 annexin A5 ANXA5 308 NM_001154 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072563 // endothelial microparticle // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay 200783_s_at NM_005563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005563.2 /DEF=Homo sapiens leukemia-associated phosphoprotein p18 (stathmin) (LAP18), mRNA. /FEA=mRNA /GEN=LAP18 /PROD=leukemia-associated phosphoprotein p18 /DB_XREF=gi:13518023 /UG=Hs.81915 leukemia-associated phosphoprotein p18 (stathmin) /FL=gb:NM_005563.2 gb:J04991.1 NM_005563 stathmin 1 STMN1 3925 NM_001145454 /// NM_005563 /// NM_152497 /// NM_203399 /// NM_203401 0007019 // microtubule depolymerization // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0015631 // tubulin binding // inferred from direct assay 200784_s_at BF304759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF304759 /FEA=EST /DB_XREF=gi:11251657 /DB_XREF=est:601888339F1 /CLONE=IMAGE:4122417 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1 BF304759 low density lipoprotein receptor-related protein 1 LRP1 4035 NM_002332 0001523 // retinoid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0014912 // negative regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032370 // positive regulation of lipid transport // inferred from sequence or structural similarity /// 0032374 // regulation of cholesterol transport // inferred from sequence or structural similarity /// 0032429 // regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042953 // lipoprotein transport // non-traceable author statement /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0097242 // beta-amyloid clearance // traceable author statement /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0042954 // lipoprotein transporter activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070325 // lipoprotein particle receptor binding // inferred by curator 200785_s_at NM_002332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002332.1 /DEF=Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1), mRNA. /FEA=mRNA /GEN=LRP1 /PROD=low density lipoprotein-related protein 1(alpha-2-macroglobulin receptor) /DB_XREF=gi:4758685 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1 NM_002332 low density lipoprotein receptor-related protein 1 LRP1 4035 NM_002332 0001523 // retinoid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0014912 // negative regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032370 // positive regulation of lipid transport // inferred from sequence or structural similarity /// 0032374 // regulation of cholesterol transport // inferred from sequence or structural similarity /// 0032429 // regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042953 // lipoprotein transport // non-traceable author statement /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0097242 // beta-amyloid clearance // traceable author statement /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0042954 // lipoprotein transporter activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070325 // lipoprotein particle receptor binding // inferred by curator 200786_at NM_002799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002799.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7), mRNA. /FEA=mRNA /GEN=PSMB7 /PROD=proteasome (prosome, macropain) subunit, betatype, 7 /DB_XREF=gi:4506202 /UG=Hs.118065 proteasome (prosome, macropain) subunit, beta type, 7 /FL=gb:BC000509.1 gb:D38048.1 gb:NM_002799.1 NM_002799 proteasome (prosome, macropain) subunit, beta type, 7 PSMB7 5695 NM_002799 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200787_s_at BC002426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002426.1 /DEF=Homo sapiens, phosphoprotein enriched in astrocytes 15, clone MGC:1685, mRNA, complete cds. /FEA=mRNA /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:12803230 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1 BC002426 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 /// XM_005245564 /// XM_006711598 /// XM_006711599 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 200788_s_at NM_003768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003768.1 /DEF=Homo sapiens phosphoprotein enriched in astrocytes 15 (PEA15), mRNA. /FEA=mRNA /GEN=PEA15 /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:4505704 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1 NM_003768 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 /// XM_005245564 /// XM_006711598 /// XM_006711599 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 200789_at NM_001398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001398.1 /DEF=Homo sapiens enoyl Coenzyme A hydratase 1, peroxisomal (ECH1), mRNA. /FEA=mRNA /GEN=ECH1 /PROD=peroxisomal enoyl-coenzyme A hydratase-likeprotein /DB_XREF=gi:4503446 /UG=Hs.196176 enoyl Coenzyme A hydratase 1, peroxisomal /FL=gb:NM_001398.1 gb:U16660.1 NM_001398 enoyl CoA hydratase 1, peroxisomal ECH1 1891 NM_001398 /// XM_005258610 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200790_at NM_002539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002539.1 /DEF=Homo sapiens ornithine decarboxylase 1 (ODC1) mRNA. /FEA=mRNA /GEN=ODC1 /PROD=ornithine decarboxylase 1 /DB_XREF=gi:4505488 /UG=Hs.75212 ornithine decarboxylase 1 /FL=gb:M16650.1 gb:NM_002539.1 NM_002539 ornithine decarboxylase 1 ODC1 4953 NM_001287188 /// NM_001287189 /// NM_001287190 /// NM_002539 0001822 // kidney development // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006596 // polyamine biosynthetic process // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0033387 // putrescine biosynthetic process from ornithine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004586 // ornithine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 200791_s_at NM_003870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003870.1 /DEF=Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA. /FEA=mRNA /GEN=IQGAP1 /PROD=IQ motif containing GTPase activating protein 1 /DB_XREF=gi:4506786 /UG=Hs.1742 IQ motif containing GTPase activating protein 1 /FL=gb:NM_003870.1 gb:L33075.1 NM_003870 IQ motif containing GTPase activating protein 1 IQGAP1 8826 NM_003870 /// XM_005254984 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0035305 // negative regulation of dephosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005884 // actin filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 200792_at NM_001469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001469.1 /DEF=Homo sapiens thyroid autoantigen 70kD (Ku antigen) (G22P1), mRNA. /FEA=mRNA /GEN=G22P1 /PROD=thyroid autoantigen 70kD (Ku antigen) /DB_XREF=gi:4503840 /UG=Hs.197345 thyroid autoantigen 70kD (Ku antigen) /FL=gb:J04611.1 gb:M32865.1 gb:J04607.1 gb:NM_001469.1 NM_001469 X-ray repair complementing defective repair in Chinese hamster cells 6 XRCC6 2547 NM_001288976 /// NM_001288977 /// NM_001288978 /// NM_001469 0000723 // telomere maintenance // traceable author statement /// 0006266 // DNA ligation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0071475 // cellular hyperosmotic salinity response // inferred from electronic annotation /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000783 // nuclear telomere cap complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043564 // Ku70:Ku80 complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from mutant phenotype 200793_s_at NM_001098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001098.1 /DEF=Homo sapiens aconitase 2, mitochondrial (ACO2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACO2 /PROD=aconitase 2 /DB_XREF=gi:4501866 /UG=Hs.300463 aconitase 2, mitochondrial /FL=gb:U80040.1 gb:NM_001098.1 NM_001098 aconitase 2, mitochondrial ACO2 50 NM_001098 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006101 // citrate metabolic process // inferred from direct assay /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0003994 // aconitate hydratase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 200794_x_at NM_014764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014764.1 /DEF=Homo sapiens DAZ associated protein 2 (DAZAP2), mRNA. /FEA=mRNA /GEN=DAZAP2 /PROD=DAZ associated protein 2 /DB_XREF=gi:7661885 /UG=Hs.75416 DAZ associated protein 2 /FL=gb:BC002334.1 gb:D31767.1 gb:NM_014764.1 NM_014764 DAZ associated protein 2 DAZAP2 9802 NM_001136264 /// NM_001136266 /// NM_001136267 /// NM_001136268 /// NM_001136269 /// NM_014764 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200795_at NM_004684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004684.1 /DEF=Homo sapiens SPARC-like 1 (mast9, hevin) (SPARCL1), mRNA. /FEA=mRNA /GEN=SPARCL1 /PROD=SPARC-like 1 /DB_XREF=gi:4758521 /UG=Hs.75445 SPARC-like 1 (mast9, hevin) /FL=gb:NM_004684.1 NM_004684 SPARC-like 1 (hevin) SPARCL1 8404 NM_001128310 /// NM_001291976 /// NM_001291977 /// NM_004684 0007165 // signal transduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200796_s_at BF594446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF594446 /FEA=EST /DB_XREF=gi:11686770 /DB_XREF=est:7i06c12.x1 /CLONE=IMAGE:3324694 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 BF594446 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200797_s_at AI275690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI275690 /FEA=EST /DB_XREF=gi:3897964 /DB_XREF=est:qw03a03.x1 /CLONE=IMAGE:1989964 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 AI275690 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200798_x_at NM_021960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021960.1 /DEF=Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), mRNA. /FEA=mRNA /GEN=MCL1 /PROD=myeloid cell leukemia sequence 1 (BCL2-related) /DB_XREF=gi:11386164 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 NM_021960 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200799_at NM_005345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3 NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200800_s_at NM_005345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3 NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B /// heat shock 70kDa protein 1-like HSPA1A /// HSPA1B /// HSPA1L 3303 /// 3304 /// 3305 NM_005345 /// NM_005346 /// NM_005527 /// XM_005249070 /// XM_005249071 /// XM_005249073 /// XM_005272813 /// XM_005272816 /// XM_005272817 /// XM_005274859 /// XM_005274861 /// XM_005274862 /// XM_005274970 /// XM_005274973 /// XM_005274974 /// XM_005275399 /// XM_005275401 /// XM_005275402 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0006986 // response to unfolded protein // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200801_x_at NM_001101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001101.2 /DEF=Homo sapiens actin, beta (ACTB), mRNA. /FEA=mRNA /GEN=ACTB /PROD=beta actin /DB_XREF=gi:5016088 /UG=Hs.288061 actin, beta /FL=gb:BC001301.1 gb:BC002409.1 gb:BC004251.1 gb:NM_001101.2 NM_001101 actin, beta ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 200802_at NM_006513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006513.1 /DEF=Homo sapiens seryl-tRNA synthetase (SARS), mRNA. /FEA=mRNA /GEN=SARS /PROD=seryl-tRNA synthetase /DB_XREF=gi:5730028 /UG=Hs.4888 seryl-tRNA synthetase /FL=gb:BC000716.1 gb:NM_006513.1 gb:D49914.1 NM_006513 seryl-tRNA synthetase SARS 6301 NM_006513 /// NR_034072 /// NR_034073 /// XM_006710813 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0097056 // selenocysteinyl-tRNA(Sec) biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200803_s_at AF033095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033095.1 /DEF=Homo sapiens testis enhanced gene transcript protein (TEGT) mRNA, complete cds. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript protein /DB_XREF=gi:2645728 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1 AF033095 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 /// XM_005269126 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200804_at NM_003217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003217.1 /DEF=Homo sapiens testis enhanced gene transcript (TEGT), mRNA. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript /DB_XREF=gi:4507432 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1 NM_003217 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 /// XM_005269126 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200805_at NM_006816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006816.1 /DEF=Homo sapiens endoplasmic reticulum glycoprotein (GP36B), mRNA. /FEA=mRNA /GEN=GP36B /PROD=endoplasmic reticulum glycoprotein /DB_XREF=gi:5803022 /UG=Hs.75864 endoplasmic reticulum glycoprotein /FL=gb:U10362.1 gb:NM_006816.1 NM_006816 lectin, mannose-binding 2 LMAN2 10960 NM_006816 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from mutant phenotype /// 0030246 // carbohydrate binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200806_s_at BE256479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE256479 /FEA=EST /DB_XREF=gi:9126938 /DB_XREF=est:601111293F1 /CLONE=IMAGE:3352031 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1 BE256479 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 /// XM_005246518 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200807_s_at NM_002156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002156.1 /DEF=Homo sapiens heat shock 60kD protein 1 (chaperonin) (HSPD1), mRNA. /FEA=mRNA /GEN=HSPD1 /PROD=heat shock 60kD protein 1 (chaperonin) /DB_XREF=gi:4504520 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1 NM_002156 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 /// XM_005246518 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200808_s_at NM_003461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003461.1 /DEF=Homo sapiens zyxin (ZYX), mRNA. /FEA=mRNA /GEN=ZYX /PROD=zyxin /DB_XREF=gi:4508046 /UG=Hs.75873 zyxin /FL=gb:NM_003461.1 NM_003461 zyxin ZYX 7791 NM_001010972 /// NM_003461 /// XM_005250052 /// XM_005250053 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200809_x_at NM_000976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000976.1 /DEF=Homo sapiens ribosomal protein L12 (RPL12), mRNA. /FEA=mRNA /GEN=RPL12 /PROD=ribosomal protein L12 /DB_XREF=gi:4506596 /UG=Hs.182979 ribosomal protein L12 /FL=gb:L06505.1 gb:NM_000976.1 NM_000976 ribosomal protein L12 RPL12 6136 NM_000976 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200810_s_at NM_001280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1 NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 /// XM_006722636 /// XM_006722637 /// XM_006722638 /// XR_430127 /// XR_430128 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030371 // translation repressor activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070181 // small ribosomal subunit rRNA binding // inferred from direct assay 200811_at NM_001280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1 NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 /// XM_006722636 /// XM_006722637 /// XM_006722638 /// XR_430127 /// XR_430128 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030371 // translation repressor activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070181 // small ribosomal subunit rRNA binding // inferred from direct assay 200812_at NM_006429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006429.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 7 (eta) (CCT7), mRNA. /FEA=mRNA /GEN=CCT7 /PROD=chaperonin containing TCP1, subunit 7 (eta) /DB_XREF=gi:5453606 /UG=Hs.108809 chaperonin containing TCP1, subunit 7 (eta) /FL=gb:AF026292.1 gb:NM_006429.1 NM_006429 chaperonin containing TCP1, subunit 7 (eta) CCT7 10574 NM_001009570 /// NM_001166284 /// NM_001166285 /// NM_006429 /// NR_029402 /// NR_029403 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200813_s_at BE256969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE256969 /FEA=EST /DB_XREF=gi:9127437 /DB_XREF=est:601112157F1 /CLONE=IMAGE:3352623 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 BE256969 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200814_at NM_006263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006263.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1), mRNA. /FEA=mRNA /GEN=PSME1 /PROD=proteasome (prosome, macropain) activatorsubunit 1 (PA28 alpha) /DB_XREF=gi:5453989 /UG=Hs.75348 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) /FL=gb:BC000352.1 gb:L07633.1 gb:NM_006263.1 NM_006263 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) PSME1 5720 NM_001281528 /// NM_001281529 /// NM_006263 /// NM_176783 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019884 // antigen processing and presentation of exogenous antigen // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0061133 // endopeptidase activator activity // inferred from electronic annotation 200815_s_at L13386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L13386.1 /DEF=Homo sapiens (clone 47) Miller-Dieker lissencephaly protein (LIS1) mRNA, complete cds. /FEA=mRNA /GEN=LIS1 /PROD=Miller-Dieker lissencephaly protein /DB_XREF=gi:349825 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 L13386 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200816_s_at NM_000430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000430.2 /DEF=Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) (PAFAH1B1), mRNA. /FEA=mRNA /GEN=PAFAH1B1 /PROD=platelet-activating factor acetylhydrolase,isoform Ib, alpha subunit (45kD) /DB_XREF=gi:6031206 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 NM_000430 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200817_x_at NM_001014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001014.1 /DEF=Homo sapiens ribosomal protein S10 (RPS10), mRNA. /FEA=mRNA /GEN=RPS10 /PROD=ribosomal protein S10 /DB_XREF=gi:4506678 /UG=Hs.76230 ribosomal protein S10 /FL=gb:BC001032.1 gb:BC001955.1 gb:BC005012.1 gb:NM_001014.1 gb:U14972.1 NM_001014 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200818_at NM_001697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001697.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) (ATP5O), mRNA. /FEA=mRNA /GEN=ATP5O /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, O subunit (oligomycin sensitivity conferringprotein) /DB_XREF=gi:4502302 /UG=Hs.76572 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) /FL=gb:NM_001697.1 NM_001697 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit ATP5O 539 NM_001697 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred from mutant phenotype /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation 200819_s_at NM_001018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001018.1 /DEF=Homo sapiens ribosomal protein S15 (RPS15), mRNA. /FEA=mRNA /GEN=RPS15 /PROD=ribosomal protein S15 /DB_XREF=gi:4506686 /UG=Hs.133230 ribosomal protein S15 /FL=gb:J02984.1 gb:NM_001018.1 NM_001018 ribosomal protein S15 RPS15 6209 NM_001018 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200820_at NM_002812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002812.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), mRNA. /FEA=mRNA /GEN=PSMD8 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 8 /DB_XREF=gi:4506232 /UG=Hs.78466 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 /FL=gb:D38047.1 gb:BC001164.1 gb:NM_002812.1 NM_002812 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 PSMD8 5714 NM_002812 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200821_at NM_013995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013995.1 /DEF=Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2B, mRNA. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal-associated membrane protein 2precursor /DB_XREF=gi:7669502 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:U36336.1 gb:BC002965.1 gb:NM_013995.1 NM_013995 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 200822_x_at NM_000365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000365.1 /DEF=Homo sapiens triosephosphate isomerase 1 (TPI1), mRNA. /FEA=mRNA /GEN=TPI1 /PROD=triosephosphate isomerase 1 /DB_XREF=gi:4507644 /UG=Hs.83848 triosephosphate isomerase 1 /FL=gb:BC004230.1 gb:NM_000365.1 NM_000365 triosephosphate isomerase 1 TPI1 7167 NM_000365 /// NM_001159287 /// NM_001258026 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004807 // triose-phosphate isomerase activity // not recorded /// 0004807 // triose-phosphate isomerase activity // non-traceable author statement /// 0004807 // triose-phosphate isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200823_x_at NM_000992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000992.1 /DEF=Homo sapiens ribosomal protein L29 (RPL29), mRNA. /FEA=mRNA /GEN=RPL29 /PROD=ribosomal protein L29 /DB_XREF=gi:4506628 /UG=Hs.183698 ribosomal protein L29 /FL=gb:U49083.1 gb:NM_000992.1 gb:U10248.1 NM_000992 ribosomal protein L29 RPL29 6159 NM_000992 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200824_at NM_000852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000852.2 /DEF=Homo sapiens glutathione S-transferase pi (GSTP1), mRNA. /FEA=mRNA /GEN=GSTP1 /PROD=glutathione transferase /DB_XREF=gi:6552334 /UG=Hs.226795 glutathione S-transferase pi /FL=gb:U62589.1 gb:U30897.1 gb:NM_000852.2 NM_000852 glutathione S-transferase pi 1 GSTP1 2950 NM_000852 0000302 // response to reactive oxygen species // inferred from sequence or structural similarity /// 0002674 // negative regulation of acute inflammatory response // non-traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009890 // negative regulation of biosynthetic process // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred by curator /// 0032691 // negative regulation of interleukin-1 beta production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0032930 // positive regulation of superoxide anion generation // inferred from sequence or structural similarity /// 0035726 // common myeloid progenitor cell proliferation // inferred from sequence or structural similarity /// 0035732 // nitric oxide storage // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // non-traceable author statement /// 0043508 // negative regulation of JUN kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0051771 // negative regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0060547 // negative regulation of necrotic cell death // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070664 // negative regulation of leukocyte proliferation // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097057 // TRAF2-GSTP1 complex // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0019207 // kinase regulator activity // inferred from sequence or structural similarity /// 0035730 // S-nitrosoglutathione binding // inferred from direct assay /// 0035731 // dinitrosyl-iron complex binding // inferred from direct assay /// 0070026 // nitric oxide binding // non-traceable author statement 200825_s_at NM_006389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006389.2 /DEF=Homo sapiens oxygen regulated protein (150kD) (ORP150), mRNA. /FEA=mRNA /GEN=ORP150 /PROD=oxygen regulated protein precursor /DB_XREF=gi:13699861 /UG=Hs.277704 oxygen regulated protein (150kD) /FL=gb:NM_006389.2 gb:U65785.1 NM_006389 hypoxia up-regulated 1 HYOU1 10525 NM_001130991 /// NM_006389 /// XM_005271390 /// XM_005271392 /// XM_005271393 /// XM_005271394 0002931 // response to ischemia // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200826_at NM_004597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004597.3 /DEF=Homo sapiens small nuclear ribonucleoprotein D2 polypeptide (16.5kD) (SNRPD2), mRNA. /FEA=mRNA /GEN=SNRPD2 /PROD=small nuclear ribonucleoprotein D2 polypeptide(16.5kD) /DB_XREF=gi:7242206 /UG=Hs.53125 small nuclear ribonucleoprotein D2 polypeptide (16.5kD) /FL=gb:BC000486.1 gb:BC001930.1 gb:U15008.1 gb:NM_004597.3 NM_004597 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa SNRPD2 6633 NM_004597 /// NM_177542 /// XM_005259180 0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200827_at NM_000302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000302.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) (PLOD), mRNA. /FEA=mRNA /GEN=PLOD /PROD=procollagen-lysine 5-dioxygenase /DB_XREF=gi:4557836 /UG=Hs.75093 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) /FL=gb:L06419.1 gb:NM_000302.1 NM_000302 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 PLOD1 5351 NM_000302 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // non-traceable author statement /// 0008544 // epidermis development // inferred from mutant phenotype /// 0008544 // epidermis development // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0046947 // hydroxylysine biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 200828_s_at BE871379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE871379 /FEA=EST /DB_XREF=gi:10320155 /DB_XREF=est:601449306F1 /CLONE=IMAGE:3853200 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1 BE871379 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 /// XM_005258028 /// XM_005258029 /// XM_005258030 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // inferred from mutant phenotype /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200829_x_at NM_003457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003457.1 /DEF=Homo sapiens zinc finger protein 207 (ZNF207), mRNA. /FEA=mRNA /GEN=ZNF207 /PROD=zinc finger protein 207 /DB_XREF=gi:4508016 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1 NM_003457 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 /// XM_005258028 /// XM_005258029 /// XM_005258030 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // inferred from mutant phenotype /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200830_at NM_002808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002808.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2), mRNA. /FEA=mRNA /GEN=PSMD2 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 2 /DB_XREF=gi:4506226 /UG=Hs.74619 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 /FL=gb:D78151.1 gb:BC002368.1 gb:BC002997.1 gb:NM_002808.1 gb:U18247.1 gb:U12596.1 NM_002808 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 PSMD2 5708 NM_001278708 /// NM_001278709 /// NM_002808 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 200831_s_at AA678241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA678241 /FEA=EST /DB_XREF=gi:2658763 /DB_XREF=est:zi27a06.s1 /CLONE=IMAGE:431986 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1 AA678241 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation 200832_s_at AB032261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB032261.1 /DEF=Homo sapiens Scd mRNA for stearoyl-CoA desaturase, complete cds. /FEA=mRNA /GEN=Scd /PROD=stearoyl-CoA desaturase /DB_XREF=gi:7415720 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1 AB032261 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation 200833_s_at NM_015646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015646.1 /DEF=Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), mRNA. /FEA=mRNA /GEN=RAP1B /PROD=DKFZP586H0723 protein /DB_XREF=gi:7661677 /UG=Hs.156764 RAP1B, member of RAS oncogene family /FL=gb:BC000176.2 gb:NM_015646.1 NM_015646 RAP1B, member of RAS oncogene family RAP1B 5908 NM_001010942 /// NM_001251917 /// NM_001251918 /// NM_001251921 /// NM_001251922 /// NM_015646 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from electronic annotation /// 0038180 // nerve growth factor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2001214 // positive regulation of vasculogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 200834_s_at NM_001024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001024.1 /DEF=Homo sapiens ribosomal protein S21 (RPS21), mRNA. /FEA=mRNA /GEN=RPS21 /PROD=ribosomal protein S21 /DB_XREF=gi:4506698 /UG=Hs.1948 ribosomal protein S21 /FL=gb:L04483.1 gb:NM_001024.1 NM_001024 ribosomal protein S21 RPS21 6227 NM_001024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0000461 // endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0042274 // ribosomal small subunit biogenesis // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 200835_s_at AI553791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI553791 /FEA=EST /DB_XREF=gi:4486154 /DB_XREF=est:tn29a04.x1 /CLONE=IMAGE:2169006 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1 AI553791 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200836_s_at NM_002375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002375.1 /DEF=Homo sapiens microtubule-associated protein 4 (MAP4), mRNA. /FEA=mRNA /GEN=MAP4 /PROD=microtubule-associated protein 4 /DB_XREF=gi:4505098 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1 NM_002375 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200837_at NM_005745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005745.3 /DEF=Homo sapiens accessory proteins BAP31BAP29 (DXS1357E), mRNA. /FEA=mRNA /GEN=DXS1357E /PROD=accessory proteins BAP31BAP29 /DB_XREF=gi:10047078 /UG=Hs.291904 accessory proteins BAP31BAP29 /FL=gb:NM_005745.3 NM_005745 B-cell receptor-associated protein 31 BCAP31 10134 NM_001139441 /// NM_001139457 /// NM_001256447 /// NM_005745 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200838_at NM_001908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1 NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 200839_s_at NM_001908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1 NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 200840_at NM_005548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005548.1 /DEF=Homo sapiens lysyl-tRNA synthetase (KARS), mRNA. /FEA=mRNA /GEN=KARS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:5031814 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:BC004132.1 gb:D32053.1 gb:NM_005548.1 NM_005548 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200841_s_at AI142677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI142677 /FEA=EST /DB_XREF=gi:3659036 /DB_XREF=est:ok33h03.s1 /CLONE=IMAGE:1509653 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI142677 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay 200842_s_at AI475965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI475965 /FEA=EST /DB_XREF=gi:4329010 /DB_XREF=est:tl96a09.x1 /CLONE=IMAGE:2154904 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI475965 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay 200843_s_at NM_004446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004446.1 /DEF=Homo sapiens glutamyl-prolyl-tRNA synthetase (EPRS), mRNA. /FEA=mRNA /GEN=EPRS /PROD=glutamyl-prolyl tRNA synthetase /DB_XREF=gi:4758293 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 NM_004446 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay 200844_s_at BE869583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE869583 /FEA=EST /DB_XREF=gi:10318463 /DB_XREF=est:601445695F1 /CLONE=IMAGE:3849815 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1 BE869583 peroxiredoxin 6 PRDX6 9588 NM_004905 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200845_s_at NM_004905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004905.1 /DEF=Homo sapiens anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) (KIAA0106), mRNA. /FEA=mRNA /GEN=KIAA0106 /PROD=anti-oxidant protein 2 (non-selenium glutathioneperoxidase, acidic calcium-independent phospholipase A2) /DB_XREF=gi:4758637 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1 NM_004905 peroxiredoxin 6 PRDX6 9588 NM_004905 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200846_s_at NM_002708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002708.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, alpha isoform (PPP1CA), mRNA. /FEA=mRNA /GEN=PPP1CA /PROD=protein phosphatase 1, catalytic subunit, alphaisoform /DB_XREF=gi:4506002 /UG=Hs.183994 protein phosphatase 1, catalytic subunit, alpha isoform /FL=gb:BC001888.1 gb:BC004482.1 gb:M63960.1 gb:NM_002708.1 NM_002708 protein phosphatase 1, catalytic subunit, alpha isozyme PPP1CA 5499 NM_001008709 /// NM_002708 /// NM_206873 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200847_s_at NM_016127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016127.1 /DEF=Homo sapiens HSPC035 protein (LOC51669), mRNA. /FEA=mRNA /GEN=LOC51669 /PROD=HSPC035 protein /DB_XREF=gi:7706384 /UG=Hs.279921 HSPC035 protein /FL=gb:AF100748.1 gb:AF078855.1 gb:NM_016127.1 NM_016127 store-operated calcium entry-associated regulatory factor SARAF 51669 NM_001284239 /// NM_016127 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 2001256 // regulation of store-operated calcium entry // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from direct assay 200848_at AA479488 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA479488 /FEA=EST /DB_XREF=gi:2208044 /DB_XREF=est:zv21c09.s1 /CLONE=IMAGE:754288 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AA479488 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 200849_s_at AI589266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI589266 /FEA=EST /DB_XREF=gi:4598314 /DB_XREF=est:tr58c06.x2 /CLONE=IMAGE:2222506 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AI589266 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 200850_s_at NM_006621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006621.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase-like 1 (AHCYL1), mRNA. /FEA=mRNA /GEN=AHCYL1 /PROD=S-adenosylhomocysteine hydrolase-like 1 /DB_XREF=gi:5729723 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 NM_006621 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 200851_s_at NM_014761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014761.1 /DEF=Homo sapiens KIAA0174 gene product (KIAA0174), mRNA. /FEA=mRNA /GEN=KIAA0174 /PROD=KIAA0174 gene product /DB_XREF=gi:7661971 /UG=Hs.75824 KIAA0174 gene product /FL=gb:D79996.1 gb:BC000430.1 gb:BC004359.1 gb:NM_014761.1 NM_014761 increased sodium tolerance 1 homolog (yeast) IST1 9798 NM_001270975 /// NM_001270976 /// NM_001270977 /// NM_001270978 /// NM_001270979 /// NM_014761 0000910 // cytokinesis // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0009838 // abscission // inferred from direct assay /// 0009838 // abscission // inferred from mutant phenotype /// 0019076 // viral release from host cell // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046745 // viral capsid secondary envelopment // inferred from direct assay /// 0048672 // positive regulation of collateral sprouting // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0090543 // Flemming body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0090541 // MIT domain binding // inferred from physical interaction 200852_x_at NM_005273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005273.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2 (GNB2), mRNA. /FEA=mRNA /GEN=GNB2 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2 /DB_XREF=gi:4885282 /UG=Hs.91299 guanine nucleotide binding protein (G protein), beta polypeptide 2 /FL=gb:M16538.1 gb:M36429.1 gb:NM_005273.1 NM_005273 guanine nucleotide binding protein (G protein), beta polypeptide 2 GNB2 2783 NM_005273 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200853_at NM_002106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002106.1 /DEF=Homo sapiens H2A histone family, member Z (H2AFZ), mRNA. /FEA=mRNA /GEN=H2AFZ /PROD=H2A histone family, member Z /DB_XREF=gi:4504254 /UG=Hs.119192 H2A histone family, member Z /FL=gb:M37583.1 gb:NM_002106.1 NM_002106 H2A histone family, member Z H2AFZ 3015 NM_002106 /// XM_005262971 0006334 // nucleosome assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200854_at AB028970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028970.1 /DEF=Homo sapiens mRNA for KIAA1047 protein, partial cds. /FEA=mRNA /GEN=KIAA1047 /PROD=KIAA1047 protein /DB_XREF=gi:5689430 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 AB028970 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200855_at AW771910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW771910 /FEA=EST /DB_XREF=gi:7703971 /DB_XREF=est:hn66c11.x1 /CLONE=IMAGE:3032852 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 AW771910 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200856_x_at BF437948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF437948 /FEA=EST /DB_XREF=gi:11450465 /DB_XREF=est:7q63b10.x1 /CLONE=IMAGE:3702882 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 BF437948 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200857_s_at NM_006311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006311.1 /DEF=Homo sapiens nuclear receptor co-repressor 1 (NCOR1), mRNA. /FEA=mRNA /GEN=NCOR1 /PROD=nuclear receptor co-repressor 1 /DB_XREF=gi:5454137 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 NM_006311 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200858_s_at NM_001012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001012.1 /DEF=Homo sapiens ribosomal protein S8 (RPS8), mRNA. /FEA=mRNA /GEN=RPS8 /PROD=ribosomal protein S8 /DB_XREF=gi:4506742 /UG=Hs.151604 ribosomal protein S8 /FL=gb:NM_001012.1 NM_001012 ribosomal protein S8 /// small nucleolar RNA, C/D box 38B /// small nucleolar RNA, C/D box 55 RPS8 /// SNORD38B /// SNORD55 6202 /// 26811 /// 94163 NM_001012 /// NR_000015 /// NR_001457 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 200859_x_at NM_001456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001456.1 /DEF=Homo sapiens filamin A, alpha (actin-binding protein-280) (FLNA), mRNA. /FEA=mRNA /GEN=FLNA /PROD=filamin 1 (actin-binding protein-280) /DB_XREF=gi:4503744 /UG=Hs.195464 filamin A, alpha (actin-binding protein-280) /FL=gb:NM_001456.1 NM_001456 filamin A, alpha FLNA 2316 NM_001110556 /// NM_001456 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from direct assay /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred by curator /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097440 // apical dendrite // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from direct assay /// 0031267 // small GTPase binding // inferred from direct assay /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 200860_s_at BC000779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000779.1 /DEF=Homo sapiens, Similar to KIAA1007 protein, clone MGC:692, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA1007 protein /DB_XREF=gi:12653966 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1 BC000779 CCR4-NOT transcription complex, subunit 1 CNOT1 23019 NM_001265612 /// NM_016284 /// NM_206999 /// NR_049763 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200861_at NM_016284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016284.1 /DEF=Homo sapiens KIAA1007 protein (KIAA1007), mRNA. /FEA=mRNA /GEN=KIAA1007 /PROD=KIAA1007 protein /DB_XREF=gi:7706213 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1 NM_016284 CCR4-NOT transcription complex, subunit 1 CNOT1 23019 NM_001265612 /// NM_016284 /// NM_206999 /// NR_049763 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200862_at NM_014762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014762.1 /DEF=Homo sapiens seladin-1 (KIAA0018), mRNA. /FEA=mRNA /GEN=KIAA0018 /PROD=seladin-1 /DB_XREF=gi:13375617 /UG=Hs.75616 seladin-1 /FL=gb:AF261758.1 gb:BC004375.1 gb:NM_014762.1 NM_014762 24-dehydrocholesterol reductase DHCR24 1718 NM_014762 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // inferred from sequence or structural similarity /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from expression pattern /// 0007050 // cell cycle arrest // non-traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009888 // tissue development // inferred from mutant phenotype /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901214 // regulation of neuron death // non-traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction /// 0050614 // delta24-sterol reductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 200863_s_at AI215102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI215102 /FEA=EST /DB_XREF=gi:3778703 /DB_XREF=est:qg69g05.x1 /CLONE=IMAGE:1840472 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1 AI215102 RAB11A, member RAS oncogene family RAB11A 8766 NM_001206836 /// NM_004663 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement /// 0051223 // regulation of protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200864_s_at NM_004663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004663.1 /DEF=Homo sapiens RAB11A, member RAS oncogene family (RAB11A), mRNA. /FEA=mRNA /GEN=RAB11A /PROD=RAB11A, member RAS oncogene family /DB_XREF=gi:4758983 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1 NM_004663 RAB11A, member RAS oncogene family RAB11A 8766 NM_001206836 /// NM_004663 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement /// 0051223 // regulation of protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200865_at AI001896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI001896 /FEA=EST /DB_XREF=gi:3202367 /DB_XREF=est:ot42a05.s1 /CLONE=IMAGE:1619408 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1 AI001896 eukaryotic translation initiation factor 3, subunit F EIF3F 8665 NM_003754 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200866_s_at M32221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M32221.1 /DEF=Human saposin proteins A-D mRNA, complete cds. /FEA=mRNA /GEN=PSAP /DB_XREF=gi:337761 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1 M32221 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200867_at AL031685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031685 /DEF=Human DNA sequence from clone RP5-963K23 on chromosome 20q13.11-13.2 Contains a KRT18 (Keratin type I, Cytoskeletal 18 (Cytokeratin 18, CK18,CYK18)) pseudogene, a gene for a novel protein, the gene for spermatogenesis associated protein PD1 (KIAA0... /FEA=mRNA_2 /DB_XREF=gi:9368423 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1 AL031685 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200868_s_at NM_018683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018683.1 /DEF=Homo sapiens zinc finger protein 313 (ZNF313), mRNA. /FEA=mRNA /GEN=ZNF313 /PROD=zinc finger protein 313 /DB_XREF=gi:8923897 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1 NM_018683 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200869_at NM_000980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000980.1 /DEF=Homo sapiens ribosomal protein L18a (RPL18A), mRNA. /FEA=mRNA /GEN=RPL18A /PROD=ribosomal protein L18a /DB_XREF=gi:11415025 /UG=Hs.163593 ribosomal protein L18a /FL=gb:NM_000980.1 gb:L05093.1 NM_000980 ribosomal protein L18a /// small nucleolar RNA, H/ACA box 68 RPL18A /// SNORA68 6142 /// 26780 NM_000980 /// NR_000012 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200870_at NM_007178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007178.1 /DEF=Homo sapiens unr-interacting protein (UNRIP), mRNA. /FEA=mRNA /GEN=UNRIP /PROD=unr-interacting protein /DB_XREF=gi:6005931 /UG=Hs.3727 unr-interacting protein /FL=gb:BC000162.1 gb:AB024327.1 gb:NM_007178.1 gb:AL136691.1 gb:AF161496.1 NM_007178 serine/threonine kinase receptor associated protein STRAP 11171 NM_007178 /// XM_005253294 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200871_s_at NM_002778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002778.1 /DEF=Homo sapiens prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) (PSAP), mRNA. /FEA=mRNA /GEN=PSAP /PROD=prosaposin (variant Gaucher disease and variantmetachromatic leukodystrophy) /DB_XREF=gi:11386146 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1 NM_002778 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200872_at NM_002966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002966.1 /DEF=Homo sapiens S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) (S100A10), mRNA. /FEA=mRNA /GEN=S100A10 /PROD=S100 calcium-binding protein A10 /DB_XREF=gi:4506760 /UG=Hs.119301 S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) /FL=gb:M81457.1 gb:M38591.1 gb:NM_002966.1 NM_002966 S100 calcium binding protein A10 S100A10 6281 NM_002966 0001765 // membrane raft assembly // inferred from direct assay /// 0006900 // membrane budding // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 200873_s_at NM_006585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006585.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 8 (theta) (CCT8), mRNA. /FEA=mRNA /GEN=CCT8 /PROD=chaperonin containing TCP1, subunit 8 (theta) /DB_XREF=gi:6005726 /UG=Hs.15071 chaperonin containing TCP1, subunit 8 (theta) /FL=gb:D13627.1 gb:NM_006585.1 NM_006585 chaperonin containing TCP1, subunit 8 (theta) CCT8 10694 NM_001282907 /// NM_001282908 /// NM_001282909 /// NM_006585 0006200 // ATP catabolic process // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200874_s_at BE796327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE796327 /FEA=EST /DB_XREF=gi:10217525 /DB_XREF=est:601591928F1 /CLONE=IMAGE:3946015 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1 BE796327 microRNA 1292 /// NOP56 ribonucleoprotein /// small nucleolar RNA, C/D box 110 /// small nucleolar RNA, C/D box 57 /// small nucleolar RNA, C/D box 86 MIR1292 /// NOP56 /// SNORD110 /// SNORD57 /// SNORD86 10528 /// 26792 /// 692201 /// 692213 /// 100302138 NM_006392 /// NR_002738 /// NR_003078 /// NR_004399 /// NR_027700 /// NR_031699 0006364 // rRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200875_s_at NM_006392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006392.1 /DEF=Homo sapiens nucleolar protein (KKED repeat) (NOP56), mRNA. /FEA=mRNA /GEN=NOP56 /PROD=nucleolar protein (KKED repeat) /DB_XREF=gi:5453793 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1 NM_006392 microRNA 1292 /// NOP56 ribonucleoprotein /// small nucleolar RNA, C/D box 110 /// small nucleolar RNA, C/D box 57 /// small nucleolar RNA, C/D box 86 MIR1292 /// NOP56 /// SNORD110 /// SNORD57 /// SNORD86 10528 /// 26792 /// 692201 /// 692213 /// 100302138 NM_006392 /// NR_002738 /// NR_003078 /// NR_004399 /// NR_027700 /// NR_031699 0006364 // rRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200876_s_at NM_002793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002793.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1), mRNA. /FEA=mRNA /GEN=PSMB1 /PROD=proteasome (prosome, macropain) subunit, betatype, 1 /DB_XREF=gi:4506192 /UG=Hs.75748 proteasome (prosome, macropain) subunit, beta type, 1 /FL=gb:BC000508.1 gb:NM_002793.1 NM_002793 proteasome (prosome, macropain) subunit, beta type, 1 PSMB1 5689 NM_002793 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200877_at NM_006430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006430.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 4 (delta) (CCT4), mRNA. /FEA=mRNA /GEN=CCT4 /PROD=chaperonin containing TCP1, subunit 4 (delta) /DB_XREF=gi:5453604 /UG=Hs.79150 chaperonin containing TCP1, subunit 4 (delta) /FL=gb:U38846.1 gb:AF026291.1 gb:NM_006430.1 NM_006430 chaperonin containing TCP1, subunit 4 (delta) CCT4 10575 NM_001256721 /// NM_006430 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200878_at AF052094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052094.1 /DEF=Homo sapiens clone 23698 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360400 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1 AF052094 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 200879_s_at NM_001430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001430.1 /DEF=Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA. /FEA=mRNA /GEN=EPAS1 /PROD=endothelial PAS domain protein 1 /DB_XREF=gi:4503576 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1 NM_001430 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 200880_at AL534104 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL534104 /FEA=EST /DB_XREF=gi:12797597 /DB_XREF=est:AL534104 /CLONE=CS0DF005YF01 (3 prime) /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1 AL534104 DnaJ (Hsp40) homolog, subfamily A, member 1 DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from mutant phenotype /// 0051223 // regulation of protein transport // inferred from direct assay /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 200881_s_at NM_001539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001539.1 /DEF=Homo sapiens heat shock protein, DNAJ-like 2 (HSJ2), mRNA. /FEA=mRNA /GEN=HSJ2 /PROD=heat shock protein, DNAJ-like 2 /DB_XREF=gi:4504510 /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1 NM_001539 DnaJ (Hsp40) homolog, subfamily A, member 1 DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from mutant phenotype /// 0051223 // regulation of protein transport // inferred from direct assay /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 200882_s_at NM_002810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002810.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA. /FEA=mRNA /GEN=PSMD4 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 4 /DB_XREF=gi:5292160 /UG=Hs.148495 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 /FL=gb:BC002365.1 gb:U24704.1 gb:NM_002810.1 NM_002810 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 PSMD4 5710 NM_002810 /// NM_153822 /// XM_005245354 /// XM_006711464 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200883_at NM_003366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003366.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA. /FEA=mRNA /GEN=UQCRC2 /PROD=ubiquinol-cytochrome c reductase core proteinII /DB_XREF=gi:4507842 /UG=Hs.173554 ubiquinol-cytochrome c reductase core protein II /FL=gb:BC000484.1 gb:BC003136.1 gb:J04973.1 gb:NM_003366.1 NM_003366 ubiquinol-cytochrome c reductase core protein II UQCRC2 7385 NM_003366 0006119 // oxidative phosphorylation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200884_at NM_001823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001823.1 /DEF=Homo sapiens creatine kinase, brain (CKB), mRNA. /FEA=mRNA /GEN=CKB /PROD=creatine kinase, brain /DB_XREF=gi:4502850 /UG=Hs.173724 creatine kinase, brain /FL=gb:L47647.1 gb:BC001190.1 gb:BC004914.1 gb:M16364.1 gb:M16451.1 gb:NM_001823.1 NM_001823 creatine kinase, brain CKB 1152 NM_001823 0006600 // creatine metabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 200885_at NM_005167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005167.1 /DEF=Homo sapiens ras homolog gene family, member C (ARHC), mRNA. /FEA=mRNA /GEN=ARHC /PROD=ras homolog gene family, member C /DB_XREF=gi:4885066 /UG=Hs.179735 ras homolog gene family, member C /FL=gb:L25081.1 gb:NM_005167.1 NM_005167 ras homolog family member C RHOC 389 NM_001042678 /// NM_001042679 /// NM_175744 0000910 // cytokinesis // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200886_s_at NM_002629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002629.1 /DEF=Homo sapiens phosphoglycerate mutase 1 (brain) (PGAM1), mRNA. /FEA=mRNA /GEN=PGAM1 /PROD=phosphoglycerate mutase 1 (brain) /DB_XREF=gi:4505752 /UG=Hs.181013 phosphoglycerate mutase 1 (brain) /FL=gb:BC000455.1 gb:NM_002629.1 gb:J04173.1 NM_002629 phosphoglycerate mutase 1 (brain) PGAM1 5223 NM_002629 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0006110 // regulation of glycolytic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0043456 // regulation of pentose-phosphate shunt // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045730 // respiratory burst // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from direct assay /// 0004619 // phosphoglycerate mutase activity // inferred from mutant phenotype /// 0004619 // phosphoglycerate mutase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 200887_s_at NM_007315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007315.1 /DEF=Homo sapiens signal transducer and activator of transcription 1, 91kD (STAT1), mRNA. /FEA=mRNA /GEN=STAT1 /PROD=signal transducer and activator of transcription1, 91kD /DB_XREF=gi:6274551 /UG=Hs.21486 signal transducer and activator of transcription 1, 91kD /FL=gb:M97935.1 gb:NM_007315.1 NM_007315 signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200888_s_at NM_000978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000978.1 /DEF=Homo sapiens ribosomal protein L23 (RPL23), mRNA. /FEA=mRNA /GEN=RPL23 /PROD=ribosomal protein L23 /DB_XREF=gi:4506604 /UG=Hs.234518 ribosomal protein L23 /FL=gb:NM_000978.1 NM_000978 ribosomal protein L23 /// small nucleolar RNA, H/ACA box 21 RPL23 /// SNORA21 9349 /// 619505 NM_000978 /// NR_002576 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006610 // ribosomal protein import into nucleus // non-traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200889_s_at AI016620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI016620 /FEA=EST /DB_XREF=gi:3230956 /DB_XREF=est:ov30e10.x1 /CLONE=IMAGE:1638858 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 AI016620 signal sequence receptor, alpha SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200890_s_at AW006345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006345 /FEA=EST /DB_XREF=gi:5855123 /DB_XREF=est:wt04d05.x1 /CLONE=IMAGE:2506473 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 AW006345 signal sequence receptor, alpha SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200891_s_at NM_003144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003144.2 /DEF=Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha) (SSR1), mRNA. /FEA=mRNA /GEN=SSR1 /PROD=signal sequence receptor, alpha /DB_XREF=gi:6552340 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 NM_003144 signal sequence receptor, alpha SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200892_s_at BC000451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000451.1 /DEF=Homo sapiens, splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10, clone MGC:8454, mRNA, complete cds. /FEA=mRNA /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:12653362 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1 BC000451 transformer 2 beta homolog (Drosophila) TRA2B 6434 NM_001243879 /// NM_004593 /// XM_005247703 /// XM_006713724 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200893_at NM_004593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004593.1 /DEF=Homo sapiens splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 (SFRS10), mRNA. /FEA=mRNA /GEN=SFRS10 /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:4759097 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1 NM_004593 transformer 2 beta homolog (Drosophila) TRA2B 6434 NM_001243879 /// NM_004593 /// XM_005247703 /// XM_006713724 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200894_s_at AA894574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA894574 /FEA=EST /DB_XREF=gi:3030975 /DB_XREF=est:of91h10.s1 /CLONE=IMAGE:1437763 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1 AA894574 FK506 binding protein 4, 59kDa FKBP4 2288 NM_002014 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0031111 // negative regulation of microtubule polymerization or depolymerization // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from direct assay 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0032767 // copper-dependent protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048156 // tau protein binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 200895_s_at NM_002014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002014.1 /DEF=Homo sapiens FK506-binding protein 4 (59kD) (FKBP4), mRNA. /FEA=mRNA /GEN=FKBP4 /PROD=FK506-binding protein 4 (59kD) /DB_XREF=gi:4503728 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1 NM_002014 FK506 binding protein 4, 59kDa FKBP4 2288 NM_002014 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0031111 // negative regulation of microtubule polymerization or depolymerization // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from direct assay 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0032767 // copper-dependent protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048156 // tau protein binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 200896_x_at NM_004494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004494.1 /DEF=Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF), mRNA. /FEA=mRNA /GEN=HDGF /PROD=hepatoma-derived growth factor (high-mobilitygroup protein 1-like) /DB_XREF=gi:4758515 /UG=Hs.89525 hepatoma-derived growth factor (high-mobility group protein 1-like) /FL=gb:NM_004494.1 gb:D16431.1 NM_004494 hepatoma-derived growth factor HDGF 3068 NM_001126050 /// NM_001126051 /// NM_004494 /// XM_006711280 /// XM_006711281 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200897_s_at NM_016081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016081.1 /DEF=Homo sapiens palladin (KIAA0992), mRNA. /FEA=mRNA /GEN=KIAA0992 /PROD=palladin /DB_XREF=gi:7706354 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 NM_016081 palladin, cytoskeletal associated protein PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200898_s_at AK002091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002091.1 /DEF=Homo sapiens cDNA FLJ11229 fis, clone PLACE1008356, highly similar to Homo sapiens mRNA for KIAA0679 protein. /FEA=mRNA /DB_XREF=gi:7023763 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1 AK002091 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 /// XR_246060 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010616 // negative regulation of cardiac muscle adaptation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031343 // positive regulation of cell killing // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043243 // positive regulation of protein complex disassembly // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060051 // negative regulation of protein glycosylation // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0070265 // necrotic cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 200899_s_at NM_012215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012215.1 /DEF=Homo sapiens meningioma expressed antigen 5 (hyaluronidase) (MGEA5), mRNA. /FEA=mRNA /GEN=MGEA5 /PROD=meningioma expressed antigen 5 (hyaluronidase) /DB_XREF=gi:11024697 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1 NM_012215 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 /// XR_246060 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010616 // negative regulation of cardiac muscle adaptation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031343 // positive regulation of cell killing // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043243 // positive regulation of protein complex disassembly // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060051 // negative regulation of protein glycosylation // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0070265 // necrotic cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 200900_s_at AI583537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI583537 /FEA=EST /DB_XREF=gi:4569434 /DB_XREF=est:ts12d03.x1 /CLONE=IMAGE:2228357 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1 AI583537 mannose-6-phosphate receptor (cation dependent) M6PR 4074 NM_001207024 /// NM_002355 /// XM_005253376 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005537 // mannose binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200901_s_at NM_002355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002355.2 /DEF=Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), mRNA. /FEA=mRNA /GEN=M6PR /PROD=cation-dependent mannose-6-phosphate receptorprecursor /DB_XREF=gi:10947032 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1 NM_002355 mannose-6-phosphate receptor (cation dependent) /// polyhomeotic homolog 1 (Drosophila) M6PR /// PHC1 1911 /// 4074 NM_001207024 /// NM_002355 /// NM_004426 /// XM_005253334 /// XM_005253336 /// XM_005253376 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200902_at NM_004261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004261.1 /DEF=Homo sapiens 15 kDa selenoprotein (SEP15), mRNA. /FEA=mRNA /GEN=SEP15 /PROD=15 kDa selenoprotein /DB_XREF=gi:4759095 /UG=Hs.90606 15 kDa selenoprotein /FL=gb:AF288991.1 gb:BC005294.1 gb:AF051894.1 gb:NM_004261.1 NM_004261 15 kDa selenoprotein SEP15 9403 NM_004261 /// NM_203341 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from direct assay 200903_s_at NM_000687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000687.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase (AHCY), mRNA. /FEA=mRNA /GEN=AHCY /PROD=S-adenosylhomocysteine hydrolase /DB_XREF=gi:9951914 /UG=Hs.172673 S-adenosylhomocysteine hydrolase /FL=gb:M61832.1 gb:NM_000687.1 NM_000687 adenosylhomocysteinase AHCY 191 NM_000687 /// NM_001161766 /// XM_005260316 /// XM_005260317 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004013 // adenosylhomocysteinase activity // traceable author statement /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 200904_at X56841 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X56841.1 /DEF=H.sapiens HLA-E gene. /FEA=mRNA /GEN=HLA-E /PROD=HLA-E /DB_XREF=gi:433491 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1 X56841 major histocompatibility complex, class I, E HLA-E 3133 NM_005516 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002476 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib // inferred from direct assay /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002717 // positive regulation of natural killer cell mediated immunity // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay 200905_x_at NM_005516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005516.1 /DEF=Homo sapiens major histocompatibility complex, class I, E (HLA-E), mRNA. /FEA=mRNA /GEN=HLA-E /PROD=major histocompatibility complex, class I, E /DB_XREF=gi:5031744 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1 NM_005516 major histocompatibility complex, class I, E HLA-E 3133 NM_005516 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002476 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib // inferred from direct assay /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002717 // positive regulation of natural killer cell mediated immunity // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay 200906_s_at AK025843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025843.1 /DEF=Homo sapiens cDNA: FLJ22190 fis, clone HRC01053. /FEA=mRNA /DB_XREF=gi:10438481 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 AK025843 palladin, cytoskeletal associated protein PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200907_s_at AU157932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157932 /FEA=EST /DB_XREF=gi:11019453 /DB_XREF=est:AU157932 /CLONE=PLACE1010217 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 AU157932 palladin, cytoskeletal associated protein PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200908_s_at BC005354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005354.1 /DEF=Homo sapiens, ribosomal protein, large P2, clone MGC:12453, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein, large P2 /DB_XREF=gi:13529169 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1 BC005354 ribosomal protein, large, P2 RPLP2 6181 NM_001004 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200909_s_at NM_001004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001004.1 /DEF=Homo sapiens ribosomal protein, large P2 (RPLP2), mRNA. /FEA=mRNA /GEN=RPLP2 /PROD=ribosomal protein, large P2 /DB_XREF=gi:4506670 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1 NM_001004 ribosomal protein, large, P2 /// small nucleolar RNA, H/ACA box 52 RPLP2 /// SNORA52 6181 /// 619565 NM_001004 /// NR_002585 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200910_at NM_005998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005998.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 3 (gamma) (CCT3), mRNA. /FEA=mRNA /GEN=CCT3 /PROD=chaperonin containing TCP1, subunit 3 (gamma) /DB_XREF=gi:5174726 /UG=Hs.1708 chaperonin containing TCP1, subunit 3 (gamma) /FL=gb:NM_005998.1 NM_005998 chaperonin containing TCP1, subunit 3 (gamma) /// uncharacterized LOC101927137 CCT3 /// LOC101927137 7203 /// 101927137 NM_001008800 /// NM_001008883 /// NM_005998 /// NR_036564 /// NR_036565 /// XR_246167 /// XR_246168 /// XR_246169 /// XR_246170 /// XR_246171 /// XR_246172 /// XR_246173 /// XR_252798 /// XR_252799 /// XR_252800 /// XR_252801 /// XR_252802 /// XR_252803 /// XR_252804 /// XR_428788 /// XR_428789 /// XR_428790 /// XR_428791 /// XR_428792 /// XR_428793 /// XR_428794 /// XR_428795 /// XR_428796 /// XR_432624 /// XR_432625 /// XR_432626 /// XR_432627 /// XR_432628 /// XR_432629 /// XR_432630 /// XR_432631 /// XR_432632 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200911_s_at NM_006283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006283.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), mRNA. /FEA=mRNA /GEN=TACC1 /PROD=transforming, acidic coiled-coil containingprotein 1 /DB_XREF=gi:5454099 /UG=Hs.173159 transforming, acidic coiled-coil containing protein 1 /FL=gb:AF049910.1 gb:NM_006283.1 NM_006283 transforming, acidic coiled-coil containing protein 1 TACC1 6867 NM_001122824 /// NM_001146216 /// NM_006283 /// XM_005273622 /// XM_005273624 /// XM_005273625 /// XM_005273626 /// XM_005273627 /// XM_005273628 /// XM_005273629 /// XM_005273630 /// XM_005273631 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200912_s_at NM_001967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001967.2 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2), mRNA. /FEA=mRNA /GEN=EIF4A2 /PROD=eukaryotic translation initiation factor 4A,isoform 2 /DB_XREF=gi:9945313 /UG=Hs.173912 eukaryotic translation initiation factor 4A, isoform 2 /FL=gb:D30655.1 gb:NM_001967.2 NM_001967 eukaryotic translation initiation factor 4A2 /// microRNA 1248 /// small nucleolar RNA, H/ACA box 4 /// small nucleolar RNA, H/ACA box 63 /// small nucleolar RNA, H/ACA box 81 /// small nucleolar RNA, C/D box 2 EIF4A2 /// MIR1248 /// SNORA4 /// SNORA63 /// SNORA81 /// SNORD2 1974 /// 6043 /// 619567 /// 619568 /// 677847 /// 100302143 NM_001967 /// NR_002586 /// NR_002587 /// NR_002588 /// NR_002989 /// NR_031650 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200913_at NM_002707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002707.1 /DEF=Homo sapiens protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), mRNA. /FEA=mRNA /GEN=PPM1G /PROD=protein phosphatase 1G (formerly 2C),magnesium-dependent, gamma isoform /DB_XREF=gi:4505998 /UG=Hs.17883 protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform /FL=gb:BC000057.1 gb:NM_002707.1 NM_002707 protein phosphatase, Mg2+/Mn2+ dependent, 1G PPM1G 5496 NM_177983 0006470 // protein dephosphorylation // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200914_x_at BF589024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF589024 /FEA=EST /DB_XREF=gi:11681348 /DB_XREF=est:naa40c08.x1 /CLONE=IMAGE:3258639 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1 BF589024 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_001271014 /// NM_004986 /// NM_182926 /// NR_073128 /// NR_073129 /// XM_006720138 /// XM_006720139 /// XM_006720140 /// XM_006720141 0007018 // microtubule-based movement // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0019894 // kinesin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200915_x_at NM_004986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004986.1 /DEF=Homo sapiens kinectin 1 (kinesin receptor) (KTN1), mRNA. /FEA=mRNA /GEN=KTN1 /PROD=kinectin 1 (kinesin receptor) /DB_XREF=gi:4826813 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1 NM_004986 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_001271014 /// NM_004986 /// NM_182926 /// NR_073128 /// NR_073129 /// XM_006720138 /// XM_006720139 /// XM_006720140 /// XM_006720141 0007018 // microtubule-based movement // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0019894 // kinesin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200916_at NM_003564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003564.1 /DEF=Homo sapiens transgelin 2 (TAGLN2), mRNA. /FEA=mRNA /GEN=TAGLN2 /PROD=transgelin 2 /DB_XREF=gi:4507356 /UG=Hs.75725 transgelin 2 /FL=gb:D21261.1 gb:NM_003564.1 NM_003564 transgelin 2 TAGLN2 8407 NM_001277223 /// NM_001277224 /// NM_003564 0007517 // muscle organ development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from direct assay 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200917_s_at BG474541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG474541 /FEA=EST /DB_XREF=gi:13406818 /DB_XREF=est:602517313F1 /CLONE=IMAGE:4649162 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1 BG474541 signal recognition particle receptor (docking protein) SRPR 6734 NM_001177842 /// NM_003139 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200918_s_at NM_003139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003139.1 /DEF=Homo sapiens signal recognition particle receptor (docking protein) (SRPR), mRNA. /FEA=mRNA /GEN=SRPR /PROD=signal recognition particle receptor (dockingprotein) /DB_XREF=gi:4507222 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1 NM_003139 signal recognition particle receptor (docking protein) SRPR 6734 NM_001177842 /// NM_003139 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200919_at NM_004427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004427.1 /DEF=Homo sapiens early development regulator 2 (homolog of polyhomeotic 2) (EDR2), mRNA. /FEA=mRNA /GEN=EDR2 /PROD=early development regulator 2 /DB_XREF=gi:4758241 /UG=Hs.75878 early development regulator 2 (homolog of polyhomeotic 2) /FL=gb:U89278.1 gb:NM_004427.1 NM_004427 polyhomeotic homolog 2 (Drosophila) PHC2 1912 NM_004427 /// NM_198040 /// XM_005270568 /// XM_005270570 /// XM_005270571 /// XM_005270572 /// XM_006710401 /// XM_006710402 /// XM_006710403 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200920_s_at AL535380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL535380 /FEA=EST /DB_XREF=gi:12798873 /DB_XREF=est:AL535380 /CLONE=CS0DF009YN13 (5 prime) /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1 AL535380 B-cell translocation gene 1, anti-proliferative BTG1 694 NM_001731 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200921_s_at NM_001731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001731.1 /DEF=Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA. /FEA=mRNA /GEN=BTG1 /PROD=B-cell translocation protein 1 /DB_XREF=gi:4502472 /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1 NM_001731 B-cell translocation gene 1, anti-proliferative BTG1 694 NM_001731 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200922_at NM_006801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006801.1 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (KDELR1), mRNA. /FEA=mRNA /GEN=KDELR1 /PROD=KDEL receptor 1 /DB_XREF=gi:5803047 /UG=Hs.78040 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 /FL=gb:NM_006801.1 NM_006801 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 KDELR1 10945 NM_006801 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200923_at NM_005567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005567.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) (LGALS3BP), mRNA. /FEA=mRNA /GEN=LGALS3BP /PROD=galectin 6 binding protein /DB_XREF=gi:6006016 /UG=Hs.79339 lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) /FL=gb:BC002403.1 gb:BC002998.1 gb:L13210.1 gb:NM_005567.2 NM_005567 lectin, galactoside-binding, soluble, 3 binding protein LGALS3BP 3959 NM_005567 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200924_s_at NM_002394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002394.1 /DEF=Homo sapiens solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (SLC3A2), mRNA. /FEA=mRNA /GEN=SLC3A2 /PROD=antigen identified by monoclonal antibodies 4F2,TRA1.10, TROP4, and T43 /DB_XREF=gi:4505140 /UG=Hs.79748 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 /FL=gb:BC001061.1 gb:J02769.1 gb:J03569.1 gb:NM_002394.1 gb:AB018010.1 NM_002394 solute carrier family 3 (amino acid transporter heavy chain), member 2 SLC3A2 6520 NM_001012661 /// NM_001012662 /// NM_001012663 /// NM_001012664 /// NM_001013251 /// NM_002394 /// NR_037193 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015804 // neutral amino acid transport // inferred from electronic annotation /// 0015827 // tryptophan transport // inferred from sequence or structural similarity /// 0016049 // cell growth // non-traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060356 // leucine import // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005432 // calcium:sodium antiporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0043169 // cation binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200925_at NM_004373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004373.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIa polypeptide 1 (COX6A1), mRNA. /FEA=mRNA /GEN=COX6A1 /PROD=cytochrome c oxidase subunit VIa polypeptide 1 /DB_XREF=gi:10047079 /UG=Hs.180714 cytochrome c oxidase subunit VIa polypeptide 1 /FL=gb:NM_004373.1 NM_004373 cytochrome c oxidase subunit VIa polypeptide 1 COX6A1 1337 NM_004373 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005751 // mitochondrial respiratory chain complex IV // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 200926_at NM_001025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001025.1 /DEF=Homo sapiens ribosomal protein S23 (RPS23), mRNA. /FEA=mRNA /GEN=RPS23 /PROD=ribosomal protein S23 /DB_XREF=gi:4506700 /UG=Hs.3463 ribosomal protein S23 /FL=gb:D14530.1 gb:NM_001025.1 NM_001025 ribosomal protein S23 RPS23 6228 NM_001025 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200927_s_at AA919115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA919115 /FEA=EST /DB_XREF=gi:3059005 /DB_XREF=est:ol85g11.s1 /CLONE=IMAGE:1536452 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AA919115 RAB14, member RAS oncogene family RAB14 51552 NM_016322 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0006895 // Golgi to endosome transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0046907 // intracellular transport // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 200928_s_at AL162081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL162081.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762K0911 (from clone DKFZp762K0911); complete cds. /FEA=mRNA /GEN=DKFZp762K0911 /PROD=hypothetical protein /DB_XREF=gi:7328165 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AL162081 RAB14, member RAS oncogene family RAB14 51552 NM_016322 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0006895 // Golgi to endosome transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0046907 // intracellular transport // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 200929_at NM_006827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006827.1 /DEF=Homo sapiens transmembrane trafficking protein (TMP21), mRNA. /FEA=mRNA /GEN=TMP21 /PROD=transmembrane trafficking protein /DB_XREF=gi:5803200 /UG=Hs.74137 transmembrane trafficking protein /FL=gb:BC001825.1 gb:NM_006827.1 NM_006827 transmembrane emp24-like trafficking protein 10 (yeast) TMED10 10972 NM_006827 0001101 // response to acid // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from sequence or structural similarity /// 0007030 // Golgi organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034205 // beta-amyloid formation // inferred from mutant phenotype /// 0035459 // cargo loading into vesicle // traceable author statement /// 0035964 // COPI-coated vesicle budding // inferred from direct assay /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0048199 // vesicle targeting, to, from or within Golgi // inferred from sequence or structural similarity /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070765 // gamma-secretase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200930_s_at AA156675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156675 /FEA=EST /DB_XREF=gi:1728354 /DB_XREF=est:zl18h03.s1 /CLONE=IMAGE:502325 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1 AA156675 vinculin VCL 7414 NM_003373 /// NM_014000 /// XM_005270142 /// XM_005270143 0002009 // morphogenesis of an epithelium // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0090136 // epithelial cell-cell adhesion // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from sequence or structural similarity 200931_s_at NM_014000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014000.1 /DEF=Homo sapiens vinculin (VCL), transcript variant meta-VCL, mRNA. /FEA=mRNA /GEN=VCL /PROD=VCL isoform meta-VCL /DB_XREF=gi:7669549 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1 NM_014000 vinculin VCL 7414 NM_003373 /// NM_014000 /// XM_005270142 /// XM_005270143 0002009 // morphogenesis of an epithelium // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0090136 // epithelial cell-cell adhesion // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from sequence or structural similarity 200932_s_at NM_006400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006400.2 /DEF=Homo sapiens dynactin 2 (p50) (DCTN2), mRNA. /FEA=mRNA /GEN=DCTN2 /PROD=dynactin 2 /DB_XREF=gi:13259506 /UG=Hs.84153 dynactin 2 (p50) /FL=gb:U50733.1 gb:BC000718.1 gb:NM_006400.2 NM_006400 dynactin 2 (p50) DCTN2 10540 NM_001261412 /// NM_001261413 /// NM_006400 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 200933_x_at NM_001007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001007.1 /DEF=Homo sapiens ribosomal protein S4, X-linked (RPS4X), mRNA. /FEA=mRNA /GEN=RPS4X /PROD=ribosomal protein S4, X-linked /DB_XREF=gi:4506724 /UG=Hs.108124 ribosomal protein S4, X-linked /FL=gb:BC000472.1 gb:BC002569.1 gb:M58458.1 gb:M22146.1 gb:NM_001007.1 NM_001007 ribosomal protein S4, X-linked RPS4X 6191 NM_001007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005844 // polysome // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200934_at NM_003472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003472.1 /DEF=Homo sapiens DEK oncogene (DNA binding) (DEK), mRNA. /FEA=mRNA /GEN=DEK /PROD=DEK oncogene (DNA binding) /DB_XREF=gi:4503248 /UG=Hs.110713 DEK oncogene (DNA binding) /FL=gb:NM_003472.1 NM_003472 DEK proto-oncogene DEK 7913 NM_001134709 /// NM_003472 /// XM_005249391 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001032 // regulation of double-strand break repair via nonhomologous end joining // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200935_at NM_004343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004343.2 /DEF=Homo sapiens calreticulin (CALR), mRNA. /FEA=mRNA /GEN=CALR /PROD=calreticulin precursor /DB_XREF=gi:5921996 /UG=Hs.16488 calreticulin /FL=gb:BC002500.1 gb:M84739.1 gb:M32294.1 gb:NM_004343.2 NM_004343 calreticulin CALR 811 NM_004343 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002502 // peptide antigen assembly with MHC class I protein complex // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from genetic interaction /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from genetic interaction /// 0045787 // positive regulation of cell cycle // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050821 // protein stabilization // traceable author statement /// 0051208 // sequestering of calcium ion // traceable author statement /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from genetic interaction /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005844 // polysome // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042824 // MHC class I peptide loading complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement /// 0071682 // endocytic vesicle lumen // traceable author statement 0001849 // complement component C1q binding // traceable author statement /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0030246 // carbohydrate binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement 200936_at NM_000973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000973.1 /DEF=Homo sapiens ribosomal protein L8 (RPL8), mRNA. /FEA=mRNA /GEN=RPL8 /PROD=ribosomal protein L8 /DB_XREF=gi:4506662 /UG=Hs.178551 ribosomal protein L8 /FL=gb:BC000077.1 gb:NM_000973.1 NM_000973 ribosomal protein L8 RPL8 6132 NM_000973 /// NM_033301 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200937_s_at NM_000969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000969.1 /DEF=Homo sapiens ribosomal protein L5 (RPL5), mRNA. /FEA=mRNA /GEN=RPL5 /PROD=ribosomal protein L5 /DB_XREF=gi:4506654 /UG=Hs.180946 ribosomal protein L5 /FL=gb:AF113210.1 gb:NM_000969.1 gb:U14966.1 NM_000969 ribosomal protein L5 /// small nucleolar RNA, C/D box 21 RPL5 /// SNORD21 6083 /// 6125 NM_000969 /// NR_000006 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200938_s_at AI920976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI920976 /FEA=EST /DB_XREF=gi:5656940 /DB_XREF=est:wo16h05.x1 /CLONE=IMAGE:2455545 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 AI920976 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200939_s_at NM_012102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012102.1 /DEF=Homo sapiens arginine-glutamic acid dipeptide (RE) repeats (RERE), mRNA. /FEA=mRNA /GEN=RERE /PROD=arginine-glutamic acid dipeptide (RE) repeats /DB_XREF=gi:6912253 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 NM_012102 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200940_s_at AB036737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB036737.1 /DEF=Homo sapiens mRNA for RERE, complete cds. /FEA=mRNA /PROD=RERE /DB_XREF=gi:8096339 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 AB036737 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200941_at AK026575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026575.1 /DEF=Homo sapiens cDNA: FLJ22922 fis, clone KAT06722. /FEA=mRNA /DB_XREF=gi:10439459 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1 AK026575 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200942_s_at NM_001537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001537.1 /DEF=Homo sapiens heat shock factor binding protein 1 (HSBP1), mRNA. /FEA=mRNA /GEN=HSBP1 /PROD=heat shock factor binding protein 1 /DB_XREF=gi:4557646 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1 NM_001537 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200943_at NM_004965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1 NM_004965 high mobility group nucleosome binding domain 1 HMGN1 3150 NM_004965 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0040034 // regulation of development, heterochronic // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 200944_s_at NM_004965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1 NM_004965 high mobility group nucleosome binding domain 1 /// uncharacterized LOC101927733 HMGN1 /// LOC101927733 3150 /// 101927733 NM_004965 /// XR_242845 /// XR_247614 /// XR_252852 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0040034 // regulation of development, heterochronic // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 200945_s_at NM_014933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014933.1 /DEF=Homo sapiens yeast Sec31p homolog (KIAA0905), mRNA. /FEA=mRNA /GEN=KIAA0905 /PROD=yeast Sec31p homolog /DB_XREF=gi:7662369 /UG=Hs.70266 yeast Sec31p homolog /FL=gb:AB018359.1 gb:NM_014933.1 gb:AF139184.1 NM_014933 SEC31 homolog A (S. cerevisiae) SEC31A 22872 NM_001077206 /// NM_001077207 /// NM_001077208 /// NM_001191049 /// NM_014933 /// NM_016211 /// XM_005262847 /// XM_005262849 /// XM_005262850 /// XM_005262851 /// XM_005262852 /// XM_005262854 /// XM_006714141 /// XM_006714142 /// XM_006714143 /// XM_006714144 /// XM_006714145 /// XM_006714146 /// XM_006714147 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030120 // vesicle coat // inferred from direct assay /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 200946_x_at AI339331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI339331 /FEA=EST /DB_XREF=gi:4076258 /DB_XREF=est:qt01g12.x1 /CLONE=IMAGE:1946374 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1 AI339331 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016639 // oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0043531 // ADP binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay 200947_s_at NM_005271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005271.1 /DEF=Homo sapiens glutamate dehydrogenase 1 (GLUD1), mRNA. /FEA=mRNA /GEN=GLUD1 /PROD=glutamate dehydrogenase 1 /DB_XREF=gi:4885280 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1 NM_005271 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016639 // oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0043531 // ADP binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay 200948_at NM_005439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005439.1 /DEF=Homo sapiens myeloid leukemia factor 2 (MLF2), mRNA. /FEA=mRNA /GEN=MLF2 /PROD=myeloid leukemia factor 2 /DB_XREF=gi:4885486 /UG=Hs.79026 myeloid leukemia factor 2 /FL=gb:BC000898.1 gb:BC002340.1 gb:U57342.1 gb:AF070539.1 gb:NM_005439.1 NM_005439 myeloid leukemia factor 2 MLF2 8079 NM_005439 /// NR_026581 0006952 // defense response // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 200949_x_at NM_001023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001023.1 /DEF=Homo sapiens ribosomal protein S20 (RPS20), mRNA. /FEA=mRNA /GEN=RPS20 /PROD=ribosomal protein S20 /DB_XREF=gi:4506696 /UG=Hs.8102 ribosomal protein S20 /FL=gb:L06498.1 gb:NM_001023.1 NM_001023 ribosomal protein S20 /// small nucleolar RNA, C/D box 54 RPS20 /// SNORD54 6224 /// 26795 NM_001023 /// NM_001146227 /// NR_002437 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200950_at NM_006409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006409.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 1A (41 kD) (ARPC1A), mRNA. /FEA=mRNA /GEN=ARPC1A /PROD=actin related protein 23 complex, subunit 1A(41 kD) /DB_XREF=gi:5454077 /UG=Hs.90370 actin related protein 23 complex, subunit 1A (41 kD) /FL=gb:NM_006409.1 NM_006409 actin related protein 2/3 complex, subunit 1A, 41kDa ARPC1A 10552 NM_001190996 /// NM_006409 0030036 // actin cytoskeleton organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200951_s_at AW026491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW026491 /FEA=EST /DB_XREF=gi:5880021 /DB_XREF=est:wv14b06.x1 /CLONE=IMAGE:2529491 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AW026491 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200952_s_at AI635187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI635187 /FEA=EST /DB_XREF=gi:4686517 /DB_XREF=est:tz22b10.x1 /CLONE=IMAGE:2289307 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AI635187 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200953_s_at NM_001759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001759.1 /DEF=Homo sapiens cyclin D2 (CCND2), mRNA. /FEA=mRNA /GEN=CCND2 /PROD=cyclin D2 /DB_XREF=gi:4502616 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 NM_001759 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200954_at NM_001694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001694.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD (ATP6L), mRNA. /FEA=mRNA /GEN=ATP6L /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 16kD /DB_XREF=gi:4502312 /UG=Hs.76159 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD /FL=gb:BC004537.1 gb:M62762.1 gb:NM_001694.1 NM_001694 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c ATP6V0C 527 NM_001198569 /// NM_001694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 200955_at NM_006839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006839.1 /DEF=Homo sapiens inner membrane protein, mitochondrial (mitofilin) (IMMT), mRNA. /FEA=mRNA /GEN=IMMT /PROD=inner membrane protein, mitochondrial(mitofilin) /DB_XREF=gi:5803114 /UG=Hs.78504 inner membrane protein, mitochondrial (mitofilin) /FL=gb:L42572.1 gb:BC002412.1 gb:D21094.1 gb:NM_006839.1 NM_006839 inner membrane protein, mitochondrial IMMT 10989 NM_001100169 /// NM_001100170 /// NM_006839 /// XM_005264110 /// XM_005264113 /// XM_005264114 0009409 // response to cold // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200956_s_at BE795648 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE795648 /FEA=EST /DB_XREF=gi:10216846 /DB_XREF=est:601590631F1 /CLONE=IMAGE:3945006 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1 BE795648 structure specific recognition protein 1 SSRP1 6749 NM_003146 /// XM_005274194 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200957_s_at NM_003146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003146.1 /DEF=Homo sapiens structure specific recognition protein 1 (SSRP1), mRNA. /FEA=mRNA /GEN=SSRP1 /PROD=structure specific recognition protein 1 /DB_XREF=gi:4507240 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1 NM_003146 structure specific recognition protein 1 SSRP1 6749 NM_003146 /// XM_005274194 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200958_s_at NM_005625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005625.1 /DEF=Homo sapiens syndecan binding protein (syntenin) (SDCBP), mRNA. /FEA=mRNA /GEN=SDCBP /PROD=syndecan binding protein (syntenin) /DB_XREF=gi:5032082 /UG=Hs.8180 syndecan binding protein (syntenin) /FL=gb:AF000652.1 gb:NM_005625.1 NM_005625 syndecan binding protein (syntenin) SDCBP 6386 NM_001007067 /// NM_001007068 /// NM_001007069 /// NM_001007070 /// NM_005625 /// XM_005251280 0006612 // protein targeting to membrane // non-traceable author statement /// 0006930 // substrate-dependent cell migration, cell extension // non-traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005895 // interleukin-5 receptor complex // inferred from sequence or structural similarity /// 0005912 // adherens junction // non-traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005137 // interleukin-5 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045545 // syndecan binding // inferred from physical interaction /// 0045545 // syndecan binding // non-traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 200959_at NM_004960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004960.1 /DEF=Homo sapiens fusion, derived from t(12;16) malignant liposarcoma (FUS), mRNA. /FEA=mRNA /GEN=FUS /PROD=fusion, derived from t(12;16) malignantliposarcoma /DB_XREF=gi:4826733 /UG=Hs.99969 fusion, derived from t(12;16) malignant liposarcoma /FL=gb:BC000402.1 gb:BC002459.1 gb:NM_004960.1 NM_004960 FUS RNA binding protein FUS 2521 NM_001010850 /// NM_001170634 /// NM_001170937 /// NM_004960 /// NR_028388 /// XM_005255233 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200960_x_at NM_007096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007096.1 /DEF=Homo sapiens clathrin, light polypeptide (Lca) (CLTA), transcript variant brain-specific, mRNA. /FEA=mRNA /GEN=CLTA /PROD=clathrin, light polypeptide A (Lca) isoform b /DB_XREF=gi:6005992 /UG=Hs.104143 clathrin, light polypeptide (Lca) /FL=gb:M20471.1 gb:NM_007096.1 NM_007096 clathrin, light chain A CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 200961_at NM_012248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012248.1 /DEF=Homo sapiens selenophosphate synthetase 2 (SPS2), mRNA. /FEA=mRNA /GEN=SPS2 /PROD=selenophosphate synthetase 2 /DB_XREF=gi:7657612 /UG=Hs.118725 selenophosphate synthetase 2 /FL=gb:BC002381.1 gb:U43286.1 gb:NM_012248.1 NM_012248 selenophosphate synthetase 2 SEPHS2 22928 NM_012248 0008152 // metabolic process // inferred from electronic annotation /// 0016260 // selenocysteine biosynthetic process // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200962_at AI348010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348010 /FEA=EST /DB_XREF=gi:4085216 /DB_XREF=est:qp61b10.x1 /CLONE=IMAGE:1927483 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1 AI348010 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200963_x_at NM_000993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000993.1 /DEF=Homo sapiens ribosomal protein L31 (RPL31), mRNA. /FEA=mRNA /GEN=RPL31 /PROD=ribosomal protein L31 /DB_XREF=gi:4506632 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1 NM_000993 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200964_at NM_003334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003334.1 /DEF=Homo sapiens ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) (UBE1), mRNA. /FEA=mRNA /GEN=UBE1 /PROD=ubiquitin-activating enzyme E1 (A1S9T and BN75temperature sensitivity complementing) /DB_XREF=gi:4507762 /UG=Hs.2055 ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) /FL=gb:M58028.1 gb:NM_003334.1 NM_003334 ubiquitin-like modifier activating enzyme 1 UBA1 7317 NM_003334 /// NM_153280 /// XM_005272648 /// XM_005272649 /// XM_005272650 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019941 // modification-dependent protein catabolic process // not recorded 0000792 // heterochromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0010008 // endosome membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030867 // rough endoplasmic reticulum membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200965_s_at NM_006720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006720.1 /DEF=Homo sapiens actin binding LIM protein 1 (ABLIM), transcript variant ABLIM-s, mRNA. /FEA=mRNA /GEN=ABLIM /PROD=actin-binding LIM protein 1, isoform s /DB_XREF=gi:5921987 /UG=Hs.158203 actin binding LIM protein 1 /FL=gb:D31883.1 gb:NM_006720.1 NM_006720 actin binding LIM protein 1 ABLIM1 3983 NM_001003407 /// NM_001003408 /// NM_002313 /// NM_006720 /// XM_005269818 /// XM_005269819 /// XM_005269820 /// XM_005269821 /// XM_005269822 /// XM_005269823 /// XM_005269824 /// XM_005269825 /// XM_005269826 /// XM_005269827 /// XM_005269828 /// XM_005269830 /// XM_006717837 /// XM_006717838 /// XM_006717839 /// XM_006717840 /// XM_006717841 /// XM_006717842 /// XM_006717843 /// XM_006717844 /// XM_006717845 /// XM_006717846 /// XM_006717847 /// XM_006717848 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200966_x_at NM_000034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000034.1 /DEF=Homo sapiens aldolase A, fructose-bisphosphate (ALDOA), mRNA. /FEA=mRNA /GEN=ALDOA /PROD=aldolase A /DB_XREF=gi:4557304 /UG=Hs.273415 aldolase A, fructose-bisphosphate /FL=gb:BC004333.1 gb:M11560.1 gb:NM_000034.1 NM_000034 aldolase A, fructose-bisphosphate ALDOA 226 NM_000034 /// NM_001127617 /// NM_001243175 /// NM_001243177 /// NM_184041 /// NM_184043 /// XM_006721109 0002576 // platelet degranulation // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from mutant phenotype /// 0006096 // glycolytic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0007015 // actin filament organization // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031430 // M band // inferred from electronic annotation /// 0031674 // I band // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015631 // tubulin binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070061 // fructose binding // inferred from direct assay 200967_at NM_000942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1 NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0000413 // protein peptidyl-prolyl isomerization // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from mutant phenotype /// 1901873 // regulation of post-translational protein modification // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032991 // macromolecular complex // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200968_s_at NM_000942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1 NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0000413 // protein peptidyl-prolyl isomerization // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from mutant phenotype /// 1901873 // regulation of post-translational protein modification // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032991 // macromolecular complex // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200969_at BG107676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG107676 /FEA=EST /DB_XREF=gi:12601522 /DB_XREF=est:602277844F1 /CLONE=IMAGE:4365370 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 BG107676 uncharacterized LOC101928061 /// stress-associated endoplasmic reticulum protein 1 LOC101928061 /// SERP1 27230 /// 101928061 NM_014445 /// XR_241595 /// XR_249518 /// XR_251476 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200970_s_at AL136807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136807.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L1621 (from clone DKFZp434L1621); complete cds. /FEA=mRNA /GEN=DKFZp434L1621 /PROD=hypothetical protein /DB_XREF=gi:12053124 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 AL136807 stress-associated endoplasmic reticulum protein 1 SERP1 27230 NM_014445 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200971_s_at NM_014445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014445.1 /DEF=Homo sapiens stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 (SERP1), mRNA. /FEA=mRNA /GEN=SERP1 /PROD=stress-associated endoplasmic reticulum protein1; ribosome associated membrane protein 4 /DB_XREF=gi:7657551 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 NM_014445 uncharacterized LOC101928061 /// stress-associated endoplasmic reticulum protein 1 LOC101928061 /// SERP1 27230 /// 101928061 NM_014445 /// XR_241595 /// XR_249518 /// XR_251476 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200972_at BC000704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000704.1 /DEF=Homo sapiens, tetraspan 3, clone MGC:965, mRNA, complete cds. /FEA=mRNA /PROD=tetraspan 3 /DB_XREF=gi:12653830 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1 BC000704 tetraspanin 3 TSPAN3 10099 NM_001168412 /// NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200973_s_at NM_005724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005724.1 /DEF=Homo sapiens tetraspan 3 (TSPAN-3), mRNA. /FEA=mRNA /GEN=TSPAN-3 /PROD=tetraspan 3 /DB_XREF=gi:5032200 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1 NM_005724 tetraspanin 3 TSPAN3 10099 NM_001168412 /// NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200974_at NM_001613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001613.1 /DEF=Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA. /FEA=mRNA /GEN=ACTA2 /PROD=alpha 2 actin /DB_XREF=gi:4501882 /UG=Hs.195851 actin, alpha 2, smooth muscle, aorta /FL=gb:J05192.1 gb:NM_001613.1 NM_001613 actin, alpha 2, smooth muscle, aorta ACTA2 59 NM_001141945 /// NM_001613 0006936 // muscle contraction // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0030240 // skeletal muscle thin filament assembly // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0055008 // cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0072144 // glomerular mesangial cell development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 200975_at NM_000310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000310.1 /DEF=Homo sapiens palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) (PPT1), mRNA. /FEA=mRNA /GEN=PPT1 /PROD=palmitoyl-protein thioesterase 1(ceroid-lipofuscinosis, neuronal 1, infantile) /DB_XREF=gi:4506030 /UG=Hs.3873 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) /FL=gb:U44772.1 gb:NM_000310.1 NM_000310 palmitoyl-protein thioesterase 1 PPT1 5538 NM_000310 /// NM_001142604 /// XM_005271007 /// XM_005271008 0002084 // protein depalmitoylation // inferred from direct assay /// 0002084 // protein depalmitoylation // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006907 // pinocytosis // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from direct assay /// 0030149 // sphingolipid catabolic process // traceable author statement /// 0030163 // protein catabolic process // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0032429 // regulation of phospholipase A2 activity // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0044265 // cellular macromolecule catabolic process // inferred from electronic annotation /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0048549 // positive regulation of pinocytosis // inferred from mutant phenotype /// 0048666 // neuron development // traceable author statement /// 0050803 // regulation of synapse structure and activity // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051181 // cofactor transport // inferred from mutant phenotype /// 0051186 // cofactor metabolic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008474 // palmitoyl-(protein) hydrolase activity // inferred from direct assay /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from sequence or structural similarity /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 200976_s_at NM_006024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006024.2 /DEF=Homo sapiens Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1), mRNA. /FEA=mRNA /GEN=TAX1BP1 /PROD=Tax1 (human T-cell leukemia virus type I)binding protein 1 /DB_XREF=gi:5803188 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1 NM_006024 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_001206901 /// NM_001206902 /// NM_006024 /// XM_005249900 0006915 // apoptotic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from sequence or structural similarity 200977_s_at AF090891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF090891.1 /DEF=Homo sapiens clone HQ0105 PRO0105 mRNA, complete cds. /FEA=mRNA /PROD=PRO0105 /DB_XREF=gi:6690159 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1 AF090891 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_001206901 /// NM_001206902 /// NM_006024 /// XM_005249900 0006915 // apoptotic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from sequence or structural similarity 200978_at NM_005917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005917.1 /DEF=Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), mRNA. /FEA=mRNA /GEN=MDH1 /PROD=malate dehydrogenase 1, NAD (soluble) /DB_XREF=gi:5174538 /UG=Hs.75375 malate dehydrogenase 1, NAD (soluble) /FL=gb:D55654.1 gb:U20352.1 gb:NM_005917.1 NM_005917 malate dehydrogenase 1, NAD (soluble) MDH1 4190 NM_001199111 /// NM_001199112 /// NM_005917 /// XM_005264320 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030060 // L-malate dehydrogenase activity // traceable author statement /// 0047860 // diiodophenylpyruvate reductase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 200979_at BF739979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF739979 /FEA=EST /DB_XREF=gi:12066655 /DB_XREF=est:7o41g06.x1 /CLONE=IMAGE:3576778 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1 BF739979 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 /// NM_001173454 /// NM_001173455 /// NM_001173456 /// XM_006724495 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay 0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation 200980_s_at NM_000284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000284.1 /DEF=Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), mRNA. /FEA=mRNA /GEN=PDHA1 /PROD=pyruvate dehydrogenase (lipoamide) alpha 1 /DB_XREF=gi:4505684 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1 NM_000284 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 /// NM_001173454 /// NM_001173455 /// NM_001173456 /// XM_006724495 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay 0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation 200981_x_at NM_016592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016592.1 /DEF=Homo sapiens neuroendocrine secretory protein 55 (NESP55), mRNA. /FEA=mRNA /GEN=NESP55 /PROD=neuroendocrine secretory protein 55 /DB_XREF=gi:7706588 /UG=Hs.113368 neuroendocrine secretory protein 55 /FL=gb:AF105253.1 gb:NM_016592.1 NM_016592 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 200982_s_at NM_001155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001155.2 /DEF=Homo sapiens annexin A6 (ANXA6), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANXA6 /PROD=annexin VI isoform 1 /DB_XREF=gi:4809274 /UG=Hs.118796 annexin A6 /FL=gb:J03578.1 gb:D00510.1 gb:NM_001155.2 NM_001155 annexin A6 ANXA6 309 NM_001155 /// NM_001193544 /// NM_004033 /// XM_005268432 0006816 // calcium ion transport // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from mutant phenotype /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from mutant phenotype /// 0015276 // ligand-gated ion channel activity // inferred from mutant phenotype /// 0015485 // cholesterol binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 200983_x_at BF983379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF983379 /FEA=EST /DB_XREF=gi:12386191 /DB_XREF=est:602305270F1 /CLONE=IMAGE:4396576 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 BF983379 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200984_s_at X16447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16447.1 /DEF=Human mRNA for CD59, an LY-6-like protein regulating complement membrane attack. /FEA=mRNA /PROD=precursor polypeptide (AA -25 to 103) /DB_XREF=gi:29805 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 X16447 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200985_s_at NM_000611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000611.1 /DEF=Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNA. /FEA=mRNA /GEN=CD59 /PROD=CD59 antigen p18-20 (antigen identified bymonoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /DB_XREF=gi:10835164 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 NM_000611 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200986_at NM_000062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000062.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), mRNA. /FEA=mRNA /GEN=SERPING1 /PROD=complement component 1 inhibitor precursor /DB_XREF=gi:4557378 /UG=Hs.151242 serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 /FL=gb:M13690.1 gb:M13656.1 gb:NM_000062.1 NM_000062 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 SERPING1 710 NM_000062 /// NM_001032295 0001869 // negative regulation of complement activation, lectin pathway // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045916 // negative regulation of complement activation // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 200987_x_at AA758755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA758755 /FEA=EST /DB_XREF=gi:2806618 /DB_XREF=est:ah80c08.s1 /CLONE=1321934 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1 AA758755 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 200988_s_at NM_005789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005789.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3), mRNA. /FEA=mRNA /GEN=PSME3 /PROD=proteasome (prosome, macropain) activatorsubunit 3 (PA28 gamma; Ki) /DB_XREF=gi:5031996 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1 NM_005789 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 200989_at NM_001530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001530.1 /DEF=Homo sapiens hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), mRNA. /FEA=mRNA /GEN=HIF1A /PROD=hypoxia-inducible factor 1, alpha subunit (basichelix-loop-helix transcription factor) /DB_XREF=gi:4504384 /UG=Hs.197540 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) /FL=gb:U29165.1 gb:AF304431.1 gb:NM_001530.1 gb:AF207601.1 gb:AF207602.1 gb:U22431.1 NM_001530 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) HIF1A 3091 NM_001243084 /// NM_001530 /// NM_181054 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001922 // B-1 B cell homeostasis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006110 // regulation of glycolytic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010573 // vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from mutant phenotype /// 0021502 // neural fold elevation formation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0032007 // negative regulation of TOR signaling // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from direct assay /// 0032722 // positive regulation of chemokine production // traceable author statement /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032963 // collagen metabolic process // inferred from sequence or structural similarity /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045766 // positive regulation of angiogenesis // inferred by curator /// 0045821 // positive regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045926 // negative regulation of growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051541 // elastin metabolic process // inferred from sequence or structural similarity /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from electronic annotation /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070101 // positive regulation of chemokine-mediated signaling pathway // inferred by curator /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031514 // motile cilium // inferred from electronic annotation 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 200990_at NM_005762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005762.1 /DEF=Homo sapiens KRAB-associated protein 1 (TIF1B), mRNA. /FEA=mRNA /GEN=TIF1B /PROD=KRAB-associated protein 1 /DB_XREF=gi:5032178 /UG=Hs.228059 KRAB-associated protein 1 /FL=gb:BC004978.1 gb:U78773.1 gb:U95040.1 gb:NM_005762.1 NM_005762 tripartite motif containing 28 TRIM28 10155 NM_005762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0060028 // convergent extension involved in axis elongation // inferred from electronic annotation /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0035851 // Krueppel-associated box domain binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 200991_s_at NM_014748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014748.1 /DEF=Homo sapiens KIAA0064 gene product (KIAA0064), mRNA. /FEA=mRNA /GEN=KIAA0064 /PROD=KIAA0064 gene product /DB_XREF=gi:7661889 /UG=Hs.278569 sorting nexin 17 /FL=gb:BC002524.1 gb:BC002610.1 gb:D31764.1 gb:NM_014748.1 NM_014748 sorting nexin 17 SNX17 9784 NM_001267059 /// NM_001267060 /// NM_001267061 /// NM_014748 /// NR_049782 /// NR_049783 /// NR_049784 /// NR_049785 /// NR_049786 /// NR_049787 /// NR_049788 /// XM_006712154 0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030100 // regulation of endocytosis // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 200992_at AL137335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137335.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A179 (from clone DKFZp434A179); partial cds. /FEA=mRNA /GEN=DKFZp434A179 /PROD=hypothetical protein /DB_XREF=gi:6807827 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AL137335 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200993_at AA939270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA939270 /FEA=EST /DB_XREF=gi:3099183 /DB_XREF=est:oq31b02.s1 /CLONE=IMAGE:1587915 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AA939270 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200994_at BG291787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG291787 /FEA=EST /DB_XREF=gi:13050002 /DB_XREF=est:602386007F1 /CLONE=IMAGE:4515240 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 BG291787 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200995_at AI741392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741392 /FEA=EST /DB_XREF=gi:5109680 /DB_XREF=est:wg27b08.x1 /CLONE=IMAGE:2366295 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AI741392 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200996_at NM_005721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005721.2 /DEF=Homo sapiens ARP3 (actin-related protein 3, yeast) homolog (ACTR3), mRNA. /FEA=mRNA /GEN=ACTR3 /PROD=ARP3 (actin-related protein 3, yeast) homolog /DB_XREF=gi:7262289 /UG=Hs.5321 ARP3 (actin-related protein 3, yeast) homolog /FL=gb:AF006083.1 gb:NM_005721.2 NM_005721 ARP3 actin-related protein 3 homolog (yeast) ACTR3 10096 NM_001277140 /// NM_005721 /// NR_102318 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043519 // regulation of myosin II filament organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200997_at NM_002896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002896.1 /DEF=Homo sapiens RNA binding motif protein 4 (RBM4), mRNA. /FEA=mRNA /GEN=RBM4 /PROD=RNA binding motif protein 4 /DB_XREF=gi:4506444 /UG=Hs.6106 RNA binding motif protein 4 /FL=gb:BC000307.1 gb:U89505.1 gb:NM_002896.1 NM_002896 RBM14-RBM4 readthrough /// RNA binding motif protein 4 RBM14-RBM4 /// RBM4 5936 /// 100526737 NM_001198843 /// NM_001198844 /// NM_001198845 /// NM_001198846 /// NM_002896 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0002190 // cap-independent translational initiation // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009725 // response to hormone // traceable author statement /// 0016575 // histone deacetylation // inferred from physical interaction /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0032055 // negative regulation of translation in response to stress // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045947 // negative regulation of translational initiation // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016592 // mediator complex // non-traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0035198 // miRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097157 // pre-mRNA intronic binding // inferred from direct assay /// 0097158 // pre-mRNA intronic pyrimidine-rich binding // inferred from direct assay 200998_s_at AW029619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW029619 /FEA=EST /DB_XREF=gi:5888375 /DB_XREF=est:wx14e05.x1 /CLONE=IMAGE:2543648 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1 AW029619 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200999_s_at NM_006825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006825.1 /DEF=Homo sapiens transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment (P63), mRNA. /FEA=mRNA /GEN=P63 /PROD=transmembrane protein (63kD), endoplasmicreticulumGolgi intermediate compartment /DB_XREF=gi:5803112 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1 NM_006825 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201000_at NM_001605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001605.1 /DEF=Homo sapiens alanyl-tRNA synthetase (AARS), mRNA. /FEA=mRNA /GEN=AARS /PROD=alanyl-tRNA synthetase /DB_XREF=gi:4501840 /UG=Hs.75102 alanyl-tRNA synthetase /FL=gb:D32050.1 gb:NM_001605.1 NM_001605 alanyl-tRNA synthetase AARS 16 NM_001605 /// XM_006721153 0001942 // hair follicle development // inferred from electronic annotation /// 0006400 // tRNA modification // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006419 // alanyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0034620 // cellular response to unfolded protein // inferred from electronic annotation /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004813 // alanine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201001_s_at BG164064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG164064 /FEA=EST /DB_XREF=gi:12670767 /DB_XREF=est:602341091F1 /CLONE=IMAGE:4449022 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 BG164064 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201002_s_at U39361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39361.1 /DEF=Homo sapiens DNA-binding protein (CROC-1B) mRNA, complete cds. /FEA=mRNA /GEN=CROC-1B /PROD=DNA-binding protein /DB_XREF=gi:1066081 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 U39361 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201003_x_at NM_003349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003349.2 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), transcript variant 2, mRNA. /FEA=mRNA /GEN=UBE2V1 /PROD=ubiquitin-conjugating enzyme E2 variant 1,isoform b /DB_XREF=gi:12025659 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 NM_003349 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201004_at NM_006280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006280.1 /DEF=Homo sapiens signal sequence receptor, delta (translocon-associated protein delta) (SSR4), mRNA. /FEA=mRNA /GEN=SSR4 /PROD=signal sequence receptor, delta /DB_XREF=gi:5454089 /UG=Hs.102135 signal sequence receptor, delta (translocon-associated protein delta) /FL=gb:BC003371.1 gb:NM_006280.1 NM_006280 signal sequence receptor, delta SSR4 6748 NM_001204526 /// NM_001204527 /// NM_006280 /// NR_037927 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006886 // intracellular protein transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005784 // Sec61 translocon complex // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement 201005_at NM_001769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001769.1 /DEF=Homo sapiens CD9 antigen (p24) (CD9), mRNA. /FEA=mRNA /GEN=CD9 /PROD=CD9 antigen (p24) /DB_XREF=gi:4502692 /UG=Hs.1244 CD9 antigen (p24) /FL=gb:M38690.1 gb:NM_001769.1 gb:L34068.1 NM_001769 CD9 molecule CD9 928 NM_001769 /// XM_005253814 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007338 // single fertilization // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // inferred from direct assay /// 0007342 // fusion of sperm to egg plasma membrane // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009414 // response to water deprivation // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0032504 // multicellular organism reproduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201006_at NM_005809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005809.1 /DEF=Homo sapiens peroxiredoxin 2 (PRDX2), mRNA. /FEA=mRNA /GEN=PRDX2 /PROD=peroxiredoxin 2 /DB_XREF=gi:5902725 /UG=Hs.146354 peroxiredoxin 2 /FL=gb:BC000452.1 gb:BC003022.1 gb:NM_005809.1 NM_005809 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181737 /// NM_181738 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201007_at NM_000183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000183.1 /DEF=Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB), mRNA. /FEA=mRNA /GEN=HADHB /PROD=hydroxyacyl-Coenzyme Adehydrogenase3-ketoacyl-Coenzyme Athiolaseenoyl-Coenzyme A hydratase (trifunctionalprotein), beta subunit /DB_XREF=gi:4504326 /UG=Hs.146812 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit /FL=gb:AF113209.1 gb:NM_000183.1 gb:D16481.1 NM_000183 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit HADHB 3032 NM_000183 /// NM_001281512 /// NM_001281513 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // non-traceable author statement /// 0005740 // mitochondrial envelope // traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016507 // mitochondrial fatty acid beta-oxidation multienzyme complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from electronic annotation /// 0016509 // long-chain-3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051287 // NAD binding // inferred from electronic annotation 201008_s_at AA812232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA812232 /FEA=EST /DB_XREF=gi:2881843 /DB_XREF=est:ob84h09.s1 /CLONE=IMAGE:1338113 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 AA812232 thioredoxin interacting protein TXNIP 10628 NM_006472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201009_s_at AI439556 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI439556 /FEA=EST /DB_XREF=gi:4305149 /DB_XREF=est:tc90c12.x1 /CLONE=IMAGE:2073430 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 AI439556 thioredoxin interacting protein TXNIP 10628 NM_006472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201010_s_at NM_006472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006472.1 /DEF=Homo sapiens upregulated by 1,25-dihydroxyvitamin D-3 (VDUP1), mRNA. /FEA=mRNA /GEN=VDUP1 /PROD=upregulated by 1,25-dihydroxyvitamin D-3 /DB_XREF=gi:5454161 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 NM_006472 thioredoxin interacting protein TXNIP 10628 NM_006472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201011_at NM_002950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002950.1 /DEF=Homo sapiens ribophorin I (RPN1), mRNA. /FEA=mRNA /GEN=RPN1 /PROD=ribophorin I /DB_XREF=gi:4506674 /UG=Hs.2280 ribophorin I /FL=gb:NM_002950.1 NM_002950 ribophorin I RPN1 6184 NM_002950 0006412 // translation // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201012_at NM_000700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000700.1 /DEF=Homo sapiens annexin A1 (ANXA1), mRNA. /FEA=mRNA /GEN=ANXA1 /PROD=annexin I /DB_XREF=gi:4502100 /UG=Hs.78225 annexin A1 /FL=gb:BC001275.1 gb:NM_000700.1 NM_000700 annexin A1 ANXA1 301 NM_000700 0001780 // neutrophil homeostasis // inferred from mutant phenotype /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033031 // positive regulation of neutrophil apoptotic process // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046632 // alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay /// 0097350 // neutrophil clearance // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201013_s_at AA902652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA902652 /FEA=EST /DB_XREF=gi:3037775 /DB_XREF=est:ok71a12.s1 /CLONE=IMAGE:1519390 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1 AA902652 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 /// XM_006714035 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // traceable author statement /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034023 // 5-(carboxyamino)imidazole ribonucleotide mutase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201014_s_at NM_006452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006452.1 /DEF=Homo sapiens multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase (ADE2H1), mRNA. /FEA=mRNA /GEN=ADE2H1 /PROD=multifunctional polypeptide similar to SAICARsynthetase and AIR carboxylase /DB_XREF=gi:5453538 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1 NM_006452 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 /// XM_006714035 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // traceable author statement /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034023 // 5-(carboxyamino)imidazole ribonucleotide mutase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201015_s_at NM_021991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021991.1 /DEF=Homo sapiens junction plakoglobin (JUP), transcript variant 2, mRNA. /FEA=mRNA /GEN=JUP /PROD=junction plakoglobin, isoform 1 /DB_XREF=gi:12056467 /UG=Hs.2340 junction plakoglobin /FL=gb:NM_021991.1 gb:BC000441.1 NM_021991 junction plakoglobin JUP 3728 NM_002230 /// NM_021991 /// XM_005257313 /// XM_006721871 /// XM_006721872 /// XM_006721873 /// XM_006721874 /// XM_006721875 /// XM_006721876 /// XM_006721877 /// XM_006721878 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000902 // cell morphogenesis // not recorded /// 0002159 // desmosome assembly // inferred from direct assay /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003181 // atrioventricular valve morphogenesis // not recorded /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007369 // gastrulation // not recorded /// 0007398 // ectoderm development // not recorded /// 0007399 // nervous system development // not recorded /// 0016331 // morphogenesis of embryonic epithelium // not recorded /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0043588 // skin development // not recorded /// 0045216 // cell-cell junction organization // traceable author statement /// 0048599 // oocyte development // not recorded /// 0050982 // detection of mechanical stimulus // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from sequence or structural similarity /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred by curator 0005634 // nucleus // inferred from mutant phenotype /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0005916 // fascia adherens // not recorded /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071665 // gamma-catenin-TCF7L2 complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005198 // structural molecule activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005199 // structural constituent of cell wall // inferred by curator /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 201016_at BE542684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE542684 /FEA=EST /DB_XREF=gi:9771329 /DB_XREF=est:601067180F1 /CLONE=IMAGE:3453571 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BE542684 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201017_at BG149698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG149698 /FEA=EST /DB_XREF=gi:12661728 /DB_XREF=est:nad32e01.x1 /CLONE=IMAGE:3367368 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BG149698 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201018_at AL079283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079283.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 39515. /FEA=mRNA /DB_XREF=gi:5102744 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 AL079283 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201019_s_at NM_001412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001412.1 /DEF=Homo sapiens eukaryotic translation initiation factor 1A (EIF1A), mRNA. /FEA=mRNA /GEN=EIF1A /PROD=eukaryotic translation initiation factor 1A /DB_XREF=gi:4503498 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 NM_001412 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201020_at NM_003405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003405.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH), mRNA. /FEA=mRNA /GEN=YWHAH /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, eta polypeptide /DB_XREF=gi:4507950 /UG=Hs.75544 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide /FL=gb:BC003047.1 gb:L20422.1 gb:NM_003405.1 NM_003405 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta YWHAH 7533 NM_003405 0002028 // regulation of sodium ion transport // inferred from direct assay /// 0006713 // glucocorticoid catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred by curator /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from sequence or structural similarity /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201021_s_at BF697964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF697964 /FEA=EST /DB_XREF=gi:11983372 /DB_XREF=est:602130050F1 /CLONE=IMAGE:4286556 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2 BF697964 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201022_s_at NM_006870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006870.2 /DEF=Homo sapiens destrin (actin depolymerizing factor) (ADF), mRNA. /FEA=mRNA /GEN=ADF /PROD=destrin (actin depolymerizing factor) /DB_XREF=gi:6466447 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2 NM_006870 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201023_at NM_005642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005642.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD (TAF2F), mRNA. /FEA=mRNA /GEN=TAF2F /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, F, 55kD /DB_XREF=gi:5032148 /UG=Hs.155188 TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD /FL=gb:NM_005642.1 gb:U18062.1 NM_005642 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa TAF7 6879 NM_005642 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000296 // spermine transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction 201024_x_at BG261322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG261322 /FEA=EST /DB_XREF=gi:12771138 /DB_XREF=est:602373079F1 /CLONE=IMAGE:4484563 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 BG261322 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201025_at AB018284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201026_at AB018284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201027_s_at NM_015904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015904.1 /DEF=Homo sapiens KIAA0741 gene product (IF2), mRNA. /FEA=mRNA /GEN=IF2 /PROD=translation initiation factor IF2 /DB_XREF=gi:7706231 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 NM_015904 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201028_s_at U82164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82164.1 /DEF=Human transmembrane protein CD99 type II mRNA, complete cds. /FEA=mRNA /GEN=CD99 /PROD=CD99 typeII /DB_XREF=gi:2149134 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1 U82164 CD99 molecule CD99 4267 NM_001122898 /// NM_001277710 /// NM_002414 /// XM_005274530 /// XM_005274532 /// XM_005274533 /// XM_005274534 /// XM_005274535 /// XM_005274794 /// XM_005274796 /// XM_005274797 /// XM_005274798 /// XM_005274799 /// XM_006724489 /// XM_006724490 /// XM_006724491 /// XM_006724870 /// XM_006724871 /// XM_006724872 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201029_s_at NM_002414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002414.1 /DEF=Homo sapiens antigen identified by monoclonal antibodies 12E7, F21 and O13 (MIC2), mRNA. /FEA=mRNA /GEN=MIC2 /PROD=antigen identified by monoclonal antibodies12E7, F21 and O13 /DB_XREF=gi:4505182 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1 NM_002414 CD99 molecule CD99 4267 NM_001122898 /// NM_001277710 /// NM_002414 /// XM_005274530 /// XM_005274532 /// XM_005274533 /// XM_005274534 /// XM_005274535 /// XM_005274794 /// XM_005274796 /// XM_005274797 /// XM_005274798 /// XM_005274799 /// XM_006724489 /// XM_006724490 /// XM_006724491 /// XM_006724870 /// XM_006724871 /// XM_006724872 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201030_x_at NM_002300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002300.1 /DEF=Homo sapiens lactate dehydrogenase B (LDHB), mRNA. /FEA=mRNA /GEN=LDHB /PROD=lactate dehydrogenase B /DB_XREF=gi:4557031 /UG=Hs.234489 lactate dehydrogenase B /FL=gb:BC002362.1 gb:NM_002300.1 NM_002300 lactate dehydrogenase B LDHB 3945 NM_001174097 /// NM_002300 /// XM_006719074 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004457 // lactate dehydrogenase activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201031_s_at NM_005520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005520.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H1 (H) (HNRPH1), mRNA. /FEA=mRNA /GEN=HNRPH1 /PROD=heterogeneous nuclear ribonucleoprotein H1 (H) /DB_XREF=gi:5031752 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) /FL=gb:BC001348.1 gb:L22009.1 gb:NM_005520.1 NM_005520 heterogeneous nuclear ribonucleoprotein H1 (H) HNRNPH1 3187 NM_001257293 /// NM_005520 /// XM_005265895 /// XM_005265896 /// XM_005265901 /// XM_005265902 /// XM_005265903 /// XM_006714862 /// XM_006714863 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201032_at NM_006698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006698.1 /DEF=Homo sapiens bladder cancer associated protein (BLCAP), mRNA. /FEA=mRNA /GEN=BLCAP /PROD=bladder cancer associated protein /DB_XREF=gi:5729737 /UG=Hs.5300 bladder cancer associated protein /FL=gb:AF053470.1 gb:NM_006698.1 NM_006698 bladder cancer associated protein BLCAP 10904 NM_001167820 /// NM_001167821 /// NM_001167822 /// NM_001167823 /// NM_006698 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0030262 // apoptotic nuclear changes // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201033_x_at NM_001002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001002.1 /DEF=Homo sapiens ribosomal protein, large, P0 (RPLP0), mRNA. /FEA=mRNA /GEN=RPLP0 /PROD=ribosomal protein, large, P0 /DB_XREF=gi:4506666 /UG=Hs.73742 ribosomal protein, large, P0 /FL=gb:BC000345.1 gb:BC000752.1 gb:BC001127.1 gb:AF274958.1 gb:BC001834.1 gb:M17885.1 gb:NM_001002.1 NM_001002 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201034_at BE545756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE545756 /FEA=EST /DB_XREF=gi:9774401 /DB_XREF=est:601076920F1 /CLONE=IMAGE:3462940 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 BE545756 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201035_s_at BC000306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000306.1 /DEF=Homo sapiens, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, clone MGC:8392, mRNA, complete cds. /FEA=mRNA /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:12653080 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 BC000306 hydroxyacyl-CoA dehydrogenase HADH 3033 NM_001184705 /// NM_005327 /// XM_005262972 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 201036_s_at NM_005327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005327.1 /DEF=Homo sapiens L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain (HADHSC), mRNA. /FEA=mRNA /GEN=HADHSC /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:4885386 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 NM_005327 hydroxyacyl-CoA dehydrogenase HADH 3033 NM_001184705 /// NM_005327 /// XM_005262972 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 201037_at NM_002627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002627.1 /DEF=Homo sapiens phosphofructokinase, platelet (PFKP), mRNA. /FEA=mRNA /GEN=PFKP /PROD=phosphofructokinase, platelet /DB_XREF=gi:11321600 /UG=Hs.99910 phosphofructokinase, platelet /FL=gb:NM_002627.1 gb:BC002536.1 gb:M64784.1 gb:D25328.1 NM_002627 phosphofructokinase, platelet PFKP 5214 NM_001242339 /// NM_002627 /// XM_005252465 /// XM_005252466 /// XM_005252467 /// XM_006717449 0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from sequence or structural similarity /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from sequence or structural similarity /// 0003872 // 6-phosphofructokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201038_s_at T67821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T67821 /FEA=EST /DB_XREF=gi:678969 /DB_XREF=est:yc39d08.s1 /CLONE=IMAGE:83055 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 T67821 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A ANP32A 8125 NM_006305 /// XM_006720707 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201039_s_at BF572938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF572938 /FEA=EST /DB_XREF=gi:11646661 /DB_XREF=est:602078949F2 /CLONE=IMAGE:4253100 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1 BF572938 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_001270362 /// NM_001270363 /// NM_005053 /// NR_072976 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 201040_at NM_002070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002070.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2), mRNA. /FEA=mRNA /GEN=GNAI2 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 2 /DB_XREF=gi:4504040 /UG=Hs.77269 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 /FL=gb:J03004.1 gb:NM_002070.1 NM_002070 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 GNAI2 2771 NM_001166425 /// NM_001282617 /// NM_001282618 /// NM_001282619 /// NM_001282620 /// NM_002070 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 201041_s_at NM_004417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004417.2 /DEF=Homo sapiens dual specificity phosphatase 1 (DUSP1), mRNA. /FEA=mRNA /GEN=DUSP1 /PROD=dual specificity phosphatase 1 /DB_XREF=gi:7108342 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2 NM_004417 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // /// 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from sequence or structural similarity 201042_at AL031651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031651 /DEF=Human DNA sequence from clone RP5-1054A22 on chromosome 20q11.22-12 Contains two isoforms of the gene for TGM2 (transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), ESTs, STSs, GSSs and a CpG island /FEA=mRNA_1 /DB_XREF=gi:6065866 /UG=Hs.8265 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:M55153.1 gb:NM_004613.1 AL031651 transglutaminase 2 TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from mutant phenotype /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201043_s_at NM_006305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006305.1 /DEF=Homo sapiens putative human HLA class II associated protein I (PHAP1), mRNA. /FEA=mRNA /GEN=PHAP1 /PROD=putative human HLA class II associated proteinI /DB_XREF=gi:5453879 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 NM_006305 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A ANP32A 8125 NM_006305 /// XM_006720707 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201044_x_at AA530892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA530892 /FEA=EST /DB_XREF=gi:2273598 /DB_XREF=est:ni97d11.s1 /CLONE=IMAGE:984789 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2 AA530892 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // /// 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from sequence or structural similarity 201045_s_at BF513857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF513857 /FEA=EST /DB_XREF=gi:11599036 /DB_XREF=est:UI-H-BW1-amz-e-01-0-UI.s1 /CLONE=IMAGE:3071689 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 BF513857 RAB6A, member RAS oncogene family /// RAB6C-like RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201046_s_at NM_005053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005053.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog A (RAD23A), mRNA. /FEA=mRNA /GEN=RAD23A /PROD=RAD23 (S. cerevisiae) homolog A /DB_XREF=gi:4826963 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1 NM_005053 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_001270362 /// NM_001270363 /// NM_005053 /// NR_072976 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 201047_x_at BC003617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003617.1 /DEF=Homo sapiens, RAB6, member RAS oncogene family, clone MGC:1654, mRNA, complete cds. /FEA=mRNA /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:13177663 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 BC003617 RAB6A, member RAS oncogene family /// RAB6C-like RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201048_x_at NM_002869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002869.1 /DEF=Homo sapiens RAB6, member RAS oncogene family (RAB6), mRNA. /FEA=mRNA /GEN=RAB6 /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:4506372 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 NM_002869 RAB6A, member RAS oncogene family /// RAB6C-like RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201049_s_at NM_022551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022551.1 /DEF=Homo sapiens ribosomal protein S18 (RPS18), mRNA. /FEA=mRNA /GEN=RPS18 /PROD=ribosomal protein S18 /DB_XREF=gi:11968181 /UG=Hs.275865 ribosomal protein S18 /FL=gb:NM_022551.1 NM_022551 ribosomal protein S18 RPS18 6222 NM_022551 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement 0005581 // collagen trimer // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // not recorded /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201050_at NM_012268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012268.1 /DEF=Homo sapiens similar to vaccinia virus HindIII K4L ORF (HU-K4), mRNA. /FEA=mRNA /GEN=HU-K4 /PROD=similar to vaccinia virus HindIII K4L ORF /DB_XREF=gi:7110640 /UG=Hs.74573 similar to vaccinia virus HindIII K4L ORF /FL=gb:BC000553.1 gb:U60644.1 gb:NM_012268.1 NM_012268 phospholipase D family, member 3 PLD3 23646 NM_001031696 /// NM_001291311 /// NM_012268 /// XM_005258704 /// XM_005258705 /// XM_005258706 /// XM_005258707 /// XM_005258708 /// XM_005258709 /// XM_005258710 /// XM_006723121 /// XM_006723122 /// XM_006723123 /// XM_006723124 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 201051_at BE560202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE560202 /FEA=EST /DB_XREF=gi:9803834 /DB_XREF=est:601347428F1 /CLONE=IMAGE:3688350 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 BE560202 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A ANP32A 8125 NM_006305 /// XM_006720707 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201052_s_at BG029917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG029917 /FEA=EST /DB_XREF=gi:12419014 /DB_XREF=est:602297261F1 /CLONE=IMAGE:4391534 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1 BG029917 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) PSMF1 9491 NM_006814 /// NM_178578 /// NM_178579 /// XM_005260873 /// XM_005260874 /// XM_006723664 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 1901799 // negative regulation of proteasomal protein catabolic process // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 201053_s_at NM_006814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006814.1 /DEF=Homo sapiens proteasome (prosome, macropain) inhibitor subunit 1 (PI31) (PSMF1), mRNA. /FEA=mRNA /GEN=PSMF1 /PROD=proteasome inhibitor /DB_XREF=gi:5803122 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1 NM_006814 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) PSMF1 9491 NM_006814 /// NM_178578 /// NM_178579 /// XM_005260873 /// XM_005260874 /// XM_006723664 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 1901799 // negative regulation of proteasomal protein catabolic process // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 201054_at BE966599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966599 /FEA=EST /DB_XREF=gi:11772191 /DB_XREF=est:601660283R1 /CLONE=IMAGE:3906044 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1 BE966599 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201055_s_at NM_006805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006805.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A0 (HNRPA0), mRNA. /FEA=mRNA /GEN=HNRPA0 /PROD=heterogeneous nuclear ribonucleoprotein A0 /DB_XREF=gi:5803035 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1 NM_006805 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201056_at N53479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N53479 /FEA=EST /DB_XREF=gi:1194645 /DB_XREF=est:yv42c11.s1 /CLONE=IMAGE:245396 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1 N53479 golgin B1 GOLGB1 2804 NM_001256486 /// NM_001256487 /// NM_001256488 /// NM_004487 /// XM_005247371 /// XM_005247372 /// XM_005247373 /// XM_006713587 /// XM_006713588 /// XM_006713589 /// XM_006713590 /// XM_006713591 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007030 // Golgi organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201057_s_at NM_004487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004487.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 (GOLGB1), mRNA. /FEA=mRNA /GEN=GOLGB1 /PROD=golgi autoantigen, golgin subfamily b,macrogolgin (with transmembrane signal), 1 /DB_XREF=gi:4758453 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1 NM_004487 golgin B1 GOLGB1 2804 NM_001256486 /// NM_001256487 /// NM_001256488 /// NM_004487 /// XM_005247371 /// XM_005247372 /// XM_005247373 /// XM_006713587 /// XM_006713588 /// XM_006713589 /// XM_006713590 /// XM_006713591 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007030 // Golgi organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201058_s_at NM_006097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006097.1 /DEF=Homo sapiens myosin regulatory light chain 2, smooth muscle isoform (MYRL2), mRNA. /FEA=mRNA /GEN=MYRL2 /PROD=myosin regulatory light chain 2, smooth muscleisoform /DB_XREF=gi:5174602 /UG=Hs.9615 myosin regulatory light chain 2, smooth muscle isoform /FL=gb:J02854.1 gb:NM_006097.1 NM_006097 myosin, light chain 9, regulatory MYL9 10398 NM_006097 /// NM_181526 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201059_at NM_005231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005231.1 /DEF=Homo sapiens ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) (EMS1), mRNA. /FEA=mRNA /GEN=EMS1 /PROD=cortactin /DB_XREF=gi:4885204 /UG=Hs.119257 ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) /FL=gb:M98343.1 gb:NM_005231.1 NM_005231 cortactin CTTN 2017 NM_001184740 /// NM_005231 /// NM_138565 /// XM_006718447 /// XM_006718448 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201060_x_at AI537887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI537887 /FEA=EST /DB_XREF=gi:4452022 /DB_XREF=est:tp32g06.x1 /CLONE=IMAGE:2189530 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 AI537887 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 201061_s_at M81635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 M81635 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 201062_at M81635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 M81635 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0042802 // identical protein binding // inferred from electronic annotation 201063_at NM_002901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002901.1 /DEF=Homo sapiens reticulocalbin 1, EF-hand calcium binding domain (RCN1), mRNA. /FEA=mRNA /GEN=RCN1 /PROD=reticulocalbin 1 precursor /DB_XREF=gi:4506454 /UG=Hs.167791 reticulocalbin 1, EF-hand calcium binding domain /FL=gb:D42073.1 gb:NM_002901.1 NM_002901 reticulocalbin 1, EF-hand calcium binding domain RCN1 5954 NM_002901 0001701 // in utero embryonic development // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201064_s_at NM_003819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003819.2 /DEF=Homo sapiens poly(A)-binding protein, cytoplasmic 4 (inducible form) (PABPC4), mRNA. /FEA=mRNA /GEN=PABPC4 /PROD=poly(A)-binding protein, cytoplasmic 4(inducible form) /DB_XREF=gi:6552335 /UG=Hs.169900 poly(A)-binding protein, cytoplasmic 4 (inducible form) /FL=gb:NM_003819.2 NM_003819 polyadenylate-binding protein 4-like /// poly(A) binding protein, cytoplasmic 4 (inducible form) LOC100996696 /// PABPC4 8761 /// 100996696 NM_001135653 /// NM_001135654 /// NM_003819 /// XM_005269266 /// XM_005275723 /// XM_005276424 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017130 // poly(C) RNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201065_s_at NM_001518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001518.1 /DEF=Homo sapiens general transcription factor II, i (GTF2I), mRNA. /FEA=mRNA /GEN=GTF2I /PROD=general transcription factor II, i /DB_XREF=gi:4504202 /UG=Hs.278589 general transcription factor II, i /FL=gb:U77948.1 gb:AF015553.1 gb:AF038969.1 gb:NM_001518.1 NM_001518 general transcription factor IIi /// general transcription factor IIi, pseudogene 1 /// general transcription factor II, i, pseudogene GTF2I /// GTF2IP1 /// LOC100093631 2969 /// 2970 /// 100093631 NM_001163636 /// NM_001280800 /// NM_001518 /// NM_032999 /// NM_033000 /// NM_033001 /// NR_002206 /// NR_003580 /// XM_005250291 /// XM_005250296 /// XM_006715939 /// XM_006715940 /// XM_006715941 /// XM_006715942 /// XM_006715943 /// XM_006715944 /// XM_006715945 /// XM_006715946 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 201066_at NM_001916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001916.1 /DEF=Homo sapiens cytochrome c-1 (CYC1), mRNA. /FEA=mRNA /GEN=CYC1 /PROD=cytochrome c-1 /DB_XREF=gi:4503184 /UG=Hs.289271 cytochrome c-1 /FL=gb:BC001006.1 gb:NM_001916.1 NM_001916 cytochrome c-1 CYC1 1537 NM_001916 0022904 // respiratory electron transport chain // traceable author statement /// 0033762 // response to glucagon // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0045155 // electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201067_at BF215487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF215487 /FEA=EST /DB_XREF=gi:11109176 /DB_XREF=est:601881048F1 /CLONE=IMAGE:4093691 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1 BF215487 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PSMC2 5701 NM_001204453 /// NM_002803 /// XM_005250505 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201068_s_at NM_002803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002803.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), mRNA. /FEA=mRNA /GEN=PSMC2 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 2 /DB_XREF=gi:4506208 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1 NM_002803 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PSMC2 5701 NM_001204453 /// NM_002803 /// XM_005250505 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201069_at NM_004530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004530.1 /DEF=Homo sapiens matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) (MMP2), mRNA. /FEA=mRNA /GEN=MMP2 /PROD=matrix metalloproteinase 2 preproprotein /DB_XREF=gi:11342665 /UG=Hs.111301 matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) /FL=gb:NM_004530.1 gb:BC002576.1 NM_004530 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) MMP2 4313 NM_001127891 /// NM_004530 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001955 // blood vessel maturation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201070_x_at AI739389 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI739389 /FEA=EST /DB_XREF=gi:5101370 /DB_XREF=est:wi29f09.x1 /CLONE=IMAGE:2391689 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1 AI739389 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201071_x_at NM_012433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012433.1 /DEF=Homo sapiens splicing factor 3b, subunit 1, 155kD (SF3B1), mRNA. /FEA=mRNA /GEN=SF3B1 /PROD=splicing factor 3b, subunit 1, 155kD /DB_XREF=gi:6912653 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1 NM_012433 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201072_s_at AW152160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW152160 /FEA=EST /DB_XREF=gi:6200058 /DB_XREF=est:xf75e01.x1 /CLONE=IMAGE:2623896 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AW152160 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201073_s_at AL040633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL040633 /FEA=EST /DB_XREF=gi:5409580 /DB_XREF=est:DKFZp434M2414_s1 /CLONE=DKFZp434M2414 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AL040633 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201074_at AA593983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA593983 /FEA=EST /DB_XREF=gi:2409333 /DB_XREF=est:nn16d01.s1 /CLONE=IMAGE:1084033 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AA593983 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201075_s_at NM_003074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003074.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1), mRNA. /FEA=mRNA /GEN=SMARCC1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 1 /DB_XREF=gi:4507078 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 NM_003074 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201076_at NM_005008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005008.1 /DEF=Homo sapiens non-histone chromosome protein 2 (S. cerevisiae)-like 1 (NHP2L1), mRNA. /FEA=mRNA /GEN=NHP2L1 /PROD=non-histone chromosome protein 2 (S.cerevisiae)-like 1 /DB_XREF=gi:4826859 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1 NM_005008 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) NHP2L1 4809 NM_001003796 /// NM_005008 /// XM_005261620 /// XM_006724258 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201077_s_at AF155235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155235.1 /DEF=Homo sapiens 15.5 kD RNA binding protein mRNA, complete cds. /FEA=mRNA /PROD=15.5 kD RNA binding protein /DB_XREF=gi:6318598 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1 AF155235 annexin A2 /// NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) ANXA2 /// NHP2L1 302 /// 4809 NM_001002857 /// NM_001002858 /// NM_001003796 /// NM_001136015 /// NM_004039 /// NM_005008 /// XM_005261620 /// XM_006724258 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0030515 // snoRNA binding // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201078_at NM_004800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004800.1 /DEF=Homo sapiens transmembrane 9 superfamily member 2 (TM9SF2), mRNA. /FEA=mRNA /GEN=TM9SF2 /PROD=transmembrane 9 superfamily member 2 /DB_XREF=gi:4758873 /UG=Hs.28757 transmembrane 9 superfamily member 2 /FL=gb:U81006.1 gb:NM_004800.1 NM_004800 transmembrane 9 superfamily member 2 TM9SF2 9375 NM_004800 0006810 // transport // traceable author statement 0005768 // endosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201079_at NM_004710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004710.1 /DEF=Homo sapiens synaptogyrin 2 (SYNGR2), mRNA. /FEA=mRNA /GEN=SYNGR2 /PROD=synaptogyrin 2 /DB_XREF=gi:4759201 /UG=Hs.5097 synaptogyrin 2 /FL=gb:BC000407.1 gb:NM_004710.1 NM_004710 synaptogyrin 2 SYNGR2 9144 NM_004710 /// XM_005257792 /// XM_005257793 0006605 // protein targeting // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201080_at BF338509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF338509 /FEA=EST /DB_XREF=gi:11284912 /DB_XREF=est:602034176F2 /CLONE=IMAGE:4182187 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1 BF338509 phosphatidylinositol-5-phosphate 4-kinase, type II, beta PIP4K2B 8396 NM_003559 /// NM_138687 /// XM_006722130 /// XM_006722131 /// XM_006722132 /// XM_006725363 /// XM_006725364 /// XM_006725365 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201081_s_at NM_003559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003559.1 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type II, beta (PIP5K2B), mRNA. /FEA=mRNA /GEN=PIP5K2B /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeII, beta /DB_XREF=gi:4505818 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1 NM_003559 phosphatidylinositol-5-phosphate 4-kinase, type II, beta PIP4K2B 8396 NM_003559 /// NM_138687 /// XM_006722130 /// XM_006722131 /// XM_006722132 /// XM_006725363 /// XM_006725364 /// XM_006725365 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201082_s_at NM_004082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004082.2 /DEF=Homo sapiens dynactin 1 (p150, Glued (Drosophila) homolog) (DCTN1), transcript variant 1, mRNA. /FEA=mRNA /GEN=DCTN1 /PROD=dynactin 1, isoform 1 /DB_XREF=gi:13259509 /UG=Hs.74617 dynactin 1 (p150, Glued (Drosophila) homolog) /FL=gb:NM_023019.1 gb:NM_004082.2 NM_004082 dynactin 1 /// solute carrier family 4 (sodium bicarbonate cotransporter), member 5 DCTN1 /// SLC4A5 1639 /// 57835 NM_001135040 /// NM_001135041 /// NM_001190836 /// NM_001190837 /// NM_004082 /// NM_021196 /// NM_023019 /// NM_033323 /// NM_133478 /// NM_133479 /// NR_033935 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 201083_s_at AA740754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA740754 /FEA=EST /DB_XREF=gi:2779346 /DB_XREF=est:nz03b05.s1 /CLONE=IMAGE:1286673 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 AA740754 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201084_s_at NM_014739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014739.1 /DEF=Homo sapiens KIAA0164 gene product (KIAA0164), mRNA. /FEA=mRNA /GEN=KIAA0164 /PROD=KIAA0164 gene product /DB_XREF=gi:7661957 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 NM_014739 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201085_s_at AA664291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA664291 /FEA=EST /DB_XREF=gi:2618282 /DB_XREF=est:ac08d09.s1 /CLONE=IMAGE:855857 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1 AA664291 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201086_x_at NM_003103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003103.1 /DEF=Homo sapiens SON DNA binding protein (SON), mRNA. /FEA=mRNA /GEN=SON /PROD=SON DNA binding protein /DB_XREF=gi:4507152 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1 NM_003103 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201087_at NM_002859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002859.1 /DEF=Homo sapiens paxillin (PXN), mRNA. /FEA=mRNA /GEN=PXN /PROD=paxillin /DB_XREF=gi:4506344 /UG=Hs.102497 paxillin /FL=gb:NM_002859.1 gb:U14588.1 NM_002859 paxillin PXN 5829 NM_001080855 /// NM_001243756 /// NM_002859 /// NM_025157 /// XM_005253910 /// XM_005253912 /// XM_005253913 /// XM_005253914 /// XM_005253915 /// XM_005253916 /// XM_005253917 /// XM_006719531 /// XM_006719532 /// XM_006719533 /// XM_006719534 /// XM_006719535 /// XM_006719536 /// XM_006719537 /// XM_006719538 /// XM_006719539 /// XR_243019 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051435 // BH4 domain binding // inferred from electronic annotation 201088_at NM_002266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002266.1 /DEF=Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mRNA. /FEA=mRNA /GEN=KPNA2 /PROD=karyopherin alpha 2 /DB_XREF=gi:4504896 /UG=Hs.159557 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) /FL=gb:NM_002266.1 gb:U09559.1 gb:U28386.1 NM_002266 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) KPNA2 3838 NM_002266 0000018 // regulation of DNA recombination // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201089_at NM_001693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001693.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 (ATP6B2), mRNA. /FEA=mRNA /GEN=ATP6B2 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), beta polypeptide, 5658kD, isoform 2 /DB_XREF=gi:4502310 /UG=Hs.1697 ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 /FL=gb:BC003100.1 gb:NM_001693.1 gb:L35249.1 NM_001693 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 ATP6V1B2 526 NM_001693 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005902 // microvillus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005524 // ATP binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 201090_x_at NM_006082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006082.1 /DEF=Homo sapiens tubulin, alpha, ubiquitous (K-ALPHA-1), mRNA. /FEA=mRNA /GEN=K-ALPHA-1 /PROD=tubulin, alpha, ubiquitous /DB_XREF=gi:5174476 /UG=Hs.278242 tubulin, alpha, ubiquitous /FL=gb:BC000696.1 gb:BC001128.1 gb:BC001209.1 gb:K00558.1 gb:AF081484.1 gb:NM_006082.1 NM_006082 tubulin, alpha 1b TUBA1B 10376 NM_006082 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 201091_s_at BE748755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE748755 /FEA=EST /DB_XREF=gi:10162747 /DB_XREF=est:601571933T1 /CLONE=IMAGE:3838737 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1 BE748755 chromobox homolog 3 CBX3 11335 NM_007276 /// NM_016587 /// XM_005249611 /// XM_005249612 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation 0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 1990226 // histone methyltransferase binding // inferred from physical interaction 201092_at NM_002893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002893.2 /DEF=Homo sapiens retinoblastoma-binding protein 7 (RBBP7), mRNA. /FEA=mRNA /GEN=RBBP7 /PROD=retinoblastoma-binding protein 7 /DB_XREF=gi:13259504 /UG=Hs.31314 retinoblastoma-binding protein 7 /FL=gb:U35143.1 gb:NM_002893.2 NM_002893 retinoblastoma binding protein 7 RBBP7 5931 NM_001198719 /// NM_002893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0070370 // cellular heat acclimation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016581 // NuRD complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201093_x_at NM_004168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004168.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHA /PROD=succinate dehydrogenase complex, subunit A,flavoprotein precursor /DB_XREF=gi:4759079 /UG=Hs.469 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) /FL=gb:BC001380.1 gb:L21936.1 gb:NM_004168.1 gb:D30648.1 NM_004168 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) SDHA 6389 NM_001294332 /// NM_004168 /// XM_005248329 /// XM_005248331 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from direct assay /// 0007399 // nervous system development // inferred from mutant phenotype /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0005749 // mitochondrial respiratory chain complex II // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 201094_at NM_001032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001032.1 /DEF=Homo sapiens ribosomal protein S29 (RPS29), mRNA. /FEA=mRNA /GEN=RPS29 /PROD=ribosomal protein S29 /DB_XREF=gi:4506716 /UG=Hs.539 ribosomal protein S29 /FL=gb:L31610.1 gb:NM_001032.1 gb:U14973.1 NM_001032 ribosomal protein S29 RPS29 6235 NM_001030001 /// NM_001032 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201095_at NM_004394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004394.1 /DEF=Homo sapiens death-associated protein (DAP), mRNA. /FEA=mRNA /GEN=DAP /PROD=death-associated protein /DB_XREF=gi:4758119 /UG=Hs.75189 death-associated protein /FL=gb:BC002726.1 gb:NM_004394.1 NM_004394 death-associated protein DAP 1611 NM_001291963 /// NM_004394 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0034198 // cellular response to amino acid starvation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype 0070513 // death domain binding // inferred from physical interaction 201096_s_at AL537042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL537042 /FEA=EST /DB_XREF=gi:12800535 /DB_XREF=est:AL537042 /CLONE=CS0DF017YF17 (5 prime) /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2 AL537042 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201097_s_at NM_001660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001660.2 /DEF=Homo sapiens ADP-ribosylation factor 4 (ARF4), mRNA. /FEA=mRNA /GEN=ARF4 /PROD=ADP-ribosylation factor 4 /DB_XREF=gi:6995998 /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2 NM_001660 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201098_at NM_004766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004766.1 /DEF=Homo sapiens coatomer protein complex, subunit beta 2 (beta prime) (COPB2), mRNA. /FEA=mRNA /GEN=COPB2 /PROD=coatomer protein complex, subunit beta 2 (betaprime) /DB_XREF=gi:4758031 /UG=Hs.75724 coatomer protein complex, subunit beta 2 (beta prime) /FL=gb:BC000326.1 gb:NM_004766.1 NM_004766 coatomer protein complex, subunit beta 2 (beta prime) COPB2 9276 NM_004766 /// NR_023350 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201099_at AA824386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA824386 /FEA=EST /DB_XREF=gi:2896270 /DB_XREF=est:aj29c05.s1 /CLONE=1391720 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2 AA824386 ubiquitin specific peptidase 9, X-linked USP9X 8239 NM_001039590 /// NM_001039591 /// NM_004652 /// NM_021906 /// XM_005272675 /// XM_005272676 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001764 // neuron migration // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0048675 // axon extension // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction 201100_s_at NM_004652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004652.2 /DEF=Homo sapiens ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) (USP9X), transcript variant 1, mRNA. /FEA=mRNA /GEN=USP9X /PROD=Drosophila fat facets related, X-linked, isoform1 /DB_XREF=gi:11641424 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2 NM_004652 ubiquitin specific peptidase 9, X-linked USP9X 8239 NM_001039590 /// NM_001039591 /// NM_004652 /// NM_021906 /// XM_005272675 /// XM_005272676 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001764 // neuron migration // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0048675 // axon extension // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction 201101_s_at BE963370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963370 /FEA=EST /DB_XREF=gi:11766788 /DB_XREF=est:601657132R1 /CLONE=IMAGE:3866335 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 BE963370 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201102_s_at NM_002626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002626.1 /DEF=Homo sapiens phosphofructokinase, liver (PFKL), mRNA. /FEA=mRNA /GEN=PFKL /PROD=phosphofructokinase, liver /DB_XREF=gi:4505746 /UG=Hs.155455 phosphofructokinase, liver /FL=gb:BC004920.1 gb:X15573.1 gb:NM_002626.1 NM_002626 phosphofructokinase, liver PFKL 5211 NM_001002021 /// NM_002626 /// NR_024108 /// XM_005261135 /// XM_005261136 /// XM_005261137 /// XM_006724011 /// XM_006724012 0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006002 // fructose 6-phosphate metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0003872 // 6-phosphofructokinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation /// 0070061 // fructose binding // inferred from direct assay /// 0070095 // fructose-6-phosphate binding // inferred from direct assay 201103_x_at BE299495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE299495 /FEA=EST /DB_XREF=gi:9183243 /DB_XREF=est:600944774T1 /CLONE=IMAGE:2960610 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1 BE299495 neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 12 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9 NBPF10 /// NBPF11 /// NBPF12 /// NBPF14 /// NBPF15 /// NBPF20 /// NBPF8 /// NBPF9 25832 /// 149013 /// 200030 /// 284565 /// 400818 /// 728841 /// 100132406 /// 100288142 NM_001037501 /// NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_001170755 /// NM_001277444 /// NM_001278141 /// NM_001278267 /// NM_015383 /// NM_173638 /// NM_183372 /// NR_046188 /// NR_102404 /// NR_102405 /// NR_110864 /// XM_005245096 /// XM_005245097 /// XM_005277342 /// XM_005277343 /// XM_005277344 /// XM_005277345 /// XM_005277346 /// XM_005277347 /// XM_006710872 /// XM_006711103 /// XM_006711104 /// XM_006711179 /// XM_006711180 /// XM_006711181 /// XM_006711182 /// XM_006711197 /// XM_006711265 /// XM_006711317 /// XR_254328 /// XR_426769 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201104_x_at NM_015383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015383.1 /DEF=Homo sapiens hypothetical protein (DJ328E19.C1.1), mRNA. /FEA=mRNA /GEN=DJ328E19.C1.1 /PROD=hypothetical protein /DB_XREF=gi:7657016 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1 NM_015383 neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 19 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 25, pseudogene /// neuroblastoma breakpoint family, member 26 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9 NBPF10 /// NBPF11 /// NBPF14 /// NBPF15 /// NBPF19 /// NBPF20 /// NBPF25P /// NBPF26 /// NBPF8 /// NBPF9 25832 /// 200030 /// 284565 /// 400818 /// 728841 /// 100132406 /// 100288142 /// 101060226 /// 101060684 /// 101929780 NM_001037501 /// NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_001170755 /// NM_001277444 /// NM_001278267 /// NM_015383 /// NM_173638 /// NM_183372 /// NR_046188 /// NR_102404 /// NR_102405 /// NR_104217 /// NR_110864 /// XM_003960069 /// XM_003960230 /// XM_005245096 /// XM_005245097 /// XM_005276139 /// XM_005276140 /// XM_005276167 /// XM_005276168 /// XM_005276169 /// XM_005276170 /// XM_005276171 /// XM_005276172 /// XM_005276173 /// XM_005276174 /// XM_005276175 /// XM_005276176 /// XM_005276177 /// XM_005276178 /// XM_005276179 /// XM_005276180 /// XM_005276181 /// XM_005276182 /// XM_005276183 /// XM_005276184 /// XM_005276185 /// XM_005276186 /// XM_005276187 /// XM_005277469 /// XM_005277470 /// XM_005277471 /// XM_005277472 /// XM_005277473 /// XM_005277474 /// XM_005277475 /// XM_005277476 /// XM_005277477 /// XM_005277478 /// XM_005277479 /// XM_005277480 /// XM_005277481 /// XM_005277482 /// XM_005277483 /// XM_005277484 /// XM_005277485 /// XM_005277486 /// XM_005277487 /// XM_005277488 /// XM_005277503 /// XM_005277504 /// XM_005277505 /// XM_006710872 /// XM_006711091 /// XM_006711092 /// XM_006711093 /// XM_006711094 /// XM_006711095 /// XM_006711096 /// XM_006711103 /// XM_006711104 /// XM_006711197 /// XM_006711265 /// XM_006711317 /// XM_006711707 /// XM_006711708 /// XM_006711709 /// XM_006711710 /// XM_006711711 /// XM_006711712 /// XM_006726340 /// XM_006726341 /// XM_006726342 /// XM_006726343 /// XM_006726344 /// XM_006726345 /// XM_006726360 /// XM_006726361 /// XM_006726362 /// XM_006726363 /// XM_006726364 /// XM_006726365 /// XR_426769 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201105_at NM_002305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002305.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 1 (galectin 1) (LGALS1), mRNA. /FEA=mRNA /GEN=LGALS1 /PROD=beta-galactosidase binding lectin precursor /DB_XREF=gi:6006015 /UG=Hs.227751 lectin, galactoside-binding, soluble, 1 (galectin 1) /FL=gb:BC001693.1 gb:J04456.1 gb:NM_002305.2 NM_002305 lectin, galactoside-binding, soluble, 1 LGALS1 3956 NM_002305 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034120 // positive regulation of erythrocyte aggregation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016936 // galactoside binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030395 // lactose binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201106_at NM_002085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002085.1 /DEF=Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), mRNA. /FEA=mRNA /GEN=GPX4 /PROD=glutathione peroxidase 4 /DB_XREF=gi:4504106 /UG=Hs.2706 glutathione peroxidase 4 (phospholipid hydroperoxidase) /FL=gb:NM_002085.1 NM_002085 glutathione peroxidase 4 GPX4 2879 NM_001039847 /// NM_001039848 /// NM_002085 0006325 // chromatin organization // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from electronic annotation /// 0047066 // phospholipid-hydroperoxide glutathione peroxidase activity // inferred from electronic annotation 201107_s_at AI812030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI812030 /FEA=EST /DB_XREF=gi:5398596 /DB_XREF=est:tw46c12.x1 /CLONE=IMAGE:2262742 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AI812030 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201108_s_at BF055462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055462 /FEA=EST /DB_XREF=gi:10809358 /DB_XREF=est:7j80e06.x1 /CLONE=IMAGE:3392770 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 BF055462 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201109_s_at AV726673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV726673 /FEA=EST /DB_XREF=gi:10836094 /DB_XREF=est:AV726673 /CLONE=HTCBGC12 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AV726673 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201110_s_at NM_003246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003246.1 /DEF=Homo sapiens thrombospondin 1 (THBS1), mRNA. /FEA=mRNA /GEN=THBS1 /PROD=thrombospondin 1 /DB_XREF=gi:4507484 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 NM_003246 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201111_at AF053641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053641.1 /DEF=Homo sapiens brain cellular apoptosis susceptibility protein (CSE1) mRNA, complete cds. /FEA=mRNA /GEN=CSE1 /PROD=cellular apoptosis susceptibility protein /DB_XREF=gi:3560556 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1 AF053641 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 201112_s_at NM_001316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001316.1 /DEF=Homo sapiens chromosome segregation 1 (yeast homolog)-like (CSE1L), mRNA. /FEA=mRNA /GEN=CSE1L /PROD=chromosome segregation 1 (yeast homolog)-like /DB_XREF=gi:4503072 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1 NM_001316 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 201113_at NM_003321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003321.1 /DEF=Homo sapiens Tu translation elongation factor, mitochondrial (TUFM), mRNA. /FEA=mRNA /GEN=TUFM /PROD=Tu translation elongation factor, mitochondrial /DB_XREF=gi:4507732 /UG=Hs.12084 Tu translation elongation factor, mitochondrial /FL=gb:BC001633.1 gb:NM_003321.1 gb:L38995.1 NM_003321 Tu translation elongation factor, mitochondrial TUFM 7284 NM_003321 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201114_x_at NM_002792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002792.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7), mRNA. /FEA=mRNA /GEN=PSMA7 /PROD=proteasome (prosome, macropain) subunit, alphatype, 7 /DB_XREF=gi:4506188 /UG=Hs.233952 proteasome (prosome, macropain) subunit, alpha type, 7 /FL=gb:BC004427.1 gb:AF022815.1 gb:AF054185.1 gb:NM_002792.1 NM_002792 proteasome (prosome, macropain) subunit, alpha type, 7 PSMA7 5688 NM_002792 /// NM_152255 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201115_at NM_006230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006230.1 /DEF=Homo sapiens polymerase (DNA directed), delta 2, regulatory subunit (50kD) (POLD2), mRNA. /FEA=mRNA /GEN=POLD2 /PROD=polymerase (DNA directed), delta 2, regulatorysubunit (50kD) /DB_XREF=gi:5453923 /UG=Hs.74598 polymerase (DNA directed), delta 2, regulatory subunit (50kD) /FL=gb:U21090.1 gb:BC000459.1 gb:NM_006230.1 NM_006230 polymerase (DNA directed), delta 2, accessory subunit POLD2 5425 NM_001127218 /// NM_001256879 /// NM_006230 /// XM_006715745 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043625 // delta DNA polymerase complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 201116_s_at AI922855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922855 /FEA=EST /DB_XREF=gi:5658819 /DB_XREF=est:wo14h05.x1 /CLONE=IMAGE:2455353 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1 AI922855 carboxypeptidase E CPE 1363 NM_001873 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072657 // protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 201117_s_at NM_001873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001873.1 /DEF=Homo sapiens carboxypeptidase E (CPE), mRNA. /FEA=mRNA /GEN=CPE /PROD=carboxypeptidase E precursor /DB_XREF=gi:4503008 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1 NM_001873 carboxypeptidase E CPE 1363 NM_001873 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072657 // protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 201118_at NM_002631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002631.1 /DEF=Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA. /FEA=mRNA /GEN=PGD /PROD=phosphogluconate dehydrogenase /DB_XREF=gi:4505758 /UG=Hs.75888 phosphogluconate dehydrogenase /FL=gb:BC000368.1 gb:NM_002631.1 gb:U30255.1 NM_002631 phosphogluconate dehydrogenase PGD 5226 NM_002631 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from sequence or structural similarity /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from direct assay /// 0019322 // pentose biosynthetic process // inferred from electronic annotation /// 0019521 // D-gluconate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // not recorded /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201119_s_at NM_004074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004074.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIII (COX8), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX8 /PROD=cytochrome c oxidase subunit VIII /DB_XREF=gi:4758043 /UG=Hs.81097 cytochrome c oxidase subunit VIII /FL=gb:NM_004074.1 NM_004074 cytochrome c oxidase subunit VIIIA (ubiquitous) COX8A 1351 NM_004074 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201120_s_at AL547946 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL547946 /FEA=EST /DB_XREF=gi:12882489 /DB_XREF=est:AL547946 /CLONE=CS0DI035YB22 (5 prime) /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2 AL547946 progesterone receptor membrane component 1 PGRMC1 10857 NM_001282621 /// NM_006667 0007411 // axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201121_s_at NM_006667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006667.2 /DEF=Homo sapiens progesterone binding protein (HPR6.6), mRNA. /FEA=mRNA /GEN=HPR6.6 /PROD=progesterone binding protein /DB_XREF=gi:6857798 /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2 NM_006667 progesterone receptor membrane component 1 PGRMC1 10857 NM_001282621 /// NM_006667 0007411 // axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201122_x_at BC000751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000751.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 5A, clone MGC:2453, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:12653914 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1 BC000751 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_005256509 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from sequence or structural similarity /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201123_s_at NM_001970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001970.1 /DEF=Homo sapiens eukaryotic translation initiation factor 5A (EIF5A), mRNA. /FEA=mRNA /GEN=EIF5A /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:4503544 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1 NM_001970 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_005256509 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from sequence or structural similarity /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201124_at AL048423 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL048423 /FEA=EST /DB_XREF=gi:5936493 /DB_XREF=est:DKFZp586H2324_s1 /CLONE=DKFZp586H2324 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1 AL048423 integrin, beta 5 ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201125_s_at NM_002213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002213.1 /DEF=Homo sapiens integrin, beta 5 (ITGB5), mRNA. /FEA=mRNA /GEN=ITGB5 /PROD=integrin, beta 5 /DB_XREF=gi:4504772 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1 NM_002213 integrin, beta 5 ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201126_s_at NM_002406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002406.2 /DEF=Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1), mRNA. /FEA=mRNA /GEN=MGAT1 /PROD=mannosyl (alpha-1,3-)-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:6031182 /UG=Hs.151513 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:M55621.1 gb:NM_002406.2 NM_002406 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase MGAT1 4245 NM_001114617 /// NM_001114618 /// NM_001114619 /// NM_001114620 /// NM_002406 /// XM_005265915 /// XM_005265916 /// XM_006714866 /// XM_006714867 0001701 // in utero embryonic development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006049 // UDP-N-acetylglucosamine catabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003827 // alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201127_s_at AI971281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI971281 /FEA=EST /DB_XREF=gi:5768107 /DB_XREF=est:wr27d10.x1 /CLONE=IMAGE:2488915 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1 AI971281 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 /// XM_005257393 /// XM_005257394 /// XM_005257395 0006101 // citrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009346 // citrate lyase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 201128_s_at NM_001096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001096.1 /DEF=Homo sapiens ATP citrate lyase (ACLY), mRNA. /FEA=mRNA /GEN=ACLY /PROD=ATP citrate lyase /DB_XREF=gi:4501864 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1 NM_001096 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 /// XM_005257393 /// XM_005257394 /// XM_005257395 0006101 // citrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009346 // citrate lyase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 201129_at NM_006276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006276.2 /DEF=Homo sapiens splicing factor, arginineserine-rich 7 (35kD) (SFRS7), mRNA. /FEA=mRNA /GEN=SFRS7 /PROD=splicing factor, arginineserine-rich 7 (35kD) /DB_XREF=gi:6857827 /UG=Hs.184167 splicing factor, arginineserine-rich 7 (35kD) /FL=gb:BC000997.2 gb:L22253.1 gb:NM_006276.2 NM_006276 serine/arginine-rich splicing factor 7 SRSF7 6432 NM_001031684 /// NM_001195446 /// NM_006276 /// XM_005264484 /// XM_005264485 /// XM_005264486 /// XR_426994 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201130_s_at L08599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L08599.1 /DEF=Human uvomorulin (E-cadherin) (UVO) mRNA, complete cds. /FEA=mRNA /GEN=UVO /PROD=uvomorulin /DB_XREF=gi:340184 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1 L08599 cadherin 1, type 1, E-cadherin (epithelial) CDH1 999 NM_004360 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000008 // regulation of protein localization to cell surface // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201131_s_at NM_004360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004360.1 /DEF=Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1), mRNA. /FEA=mRNA /GEN=CDH1 /PROD=cadherin 1, type 1, E-cadherin (epithelial) /DB_XREF=gi:4757959 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1 NM_004360 cadherin 1, type 1, E-cadherin (epithelial) CDH1 999 NM_004360 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000008 // regulation of protein localization to cell surface // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201132_at NM_019597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019597.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H2 (H) (HNRPH2), mRNA. /FEA=mRNA /GEN=HNRPH2 /PROD=heterogeneous nuclear ribonucleoprotein H2 (H) /DB_XREF=gi:9624997 /UG=Hs.278857 heterogeneous nuclear ribonucleoprotein H2 (H) /FL=gb:NM_019597.1 NM_019597 heterogeneous nuclear ribonucleoprotein H2 (H') /// RPL36A-HNRNPH2 readthrough HNRNPH2 /// RPL36A-HNRNPH2 3188 /// 100529097 NM_001032393 /// NM_001199973 /// NM_001199974 /// NM_019597 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201133_s_at AA142966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA142966 /FEA=EST /DB_XREF=gi:1712344 /DB_XREF=est:zl43b05.s1 /CLONE=IMAGE:504657 /UG=Hs.279849 KIAA0438 gene product /FL=gb:AB007898.1 gb:NM_014819.1 AA142966 praja ring finger 2, E3 ubiquitin protein ligase PJA2 9867 NM_014819 0007616 // long-term memory // inferred from sequence or structural similarity /// 0010738 // regulation of protein kinase A signaling // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from mutant phenotype /// 0034237 // protein kinase A regulatory subunit binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 201134_x_at NM_001867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001867.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIc (COX7C), mRNA. /FEA=mRNA /GEN=COX7C /PROD=cytochrome c oxidase subunit VIIc /DB_XREF=gi:4502992 /UG=Hs.3462 cytochrome c oxidase subunit VIIc /FL=gb:BC001005.1 gb:NM_001867.1 NM_001867 cytochrome c oxidase subunit VIIc COX7C 1350 NM_001867 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201135_at NM_004092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004092.2 /DEF=Homo sapiens enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ECHS1 /PROD=mitochondrial short-chain enoyl-coenzyme Ahydratase 1 precursor /DB_XREF=gi:12707569 /UG=Hs.76394 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial /FL=gb:NM_004092.2 gb:D13900.1 NM_004092 enoyl CoA hydratase, short chain, 1, mitochondrial ECHS1 1892 NM_004092 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation 201136_at NM_002668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002668.1 /DEF=Homo sapiens proteolipid protein 2 (colonic epithelium-enriched) (PLP2), mRNA. /FEA=mRNA /GEN=PLP2 /PROD=proteolipid protein 2 (colonicepithelium-enriched) /DB_XREF=gi:4505892 /UG=Hs.77422 proteolipid protein 2 (colonic epithelium-enriched) /FL=gb:L09604.1 gb:NM_002668.1 NM_002668 proteolipid protein 2 (colonic epithelium-enriched) PLP2 5355 NM_002668 0006811 // ion transport // traceable author statement /// 0006935 // chemotaxis // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0019956 // chemokine binding // inferred from physical interaction 201137_s_at NM_002121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002121.1 /DEF=Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA. /FEA=mRNA /GEN=HLA-DPB1 /PROD=major histocompatibility complex, class II, DPbeta 1 /DB_XREF=gi:4504404 /UG=Hs.814 major histocompatibility complex, class II, DP beta 1 /FL=gb:J03041.1 gb:M57466.1 gb:M83664.1 gb:NM_002121.1 gb:M28200.1 gb:M28202.1 NM_002121 major histocompatibility complex, class II, DP beta 1 HLA-DPB1 3115 NM_002121 /// XM_006715077 /// XM_006715078 /// XM_006725039 /// XM_006725040 /// XM_006725698 /// XM_006725699 /// XM_006725816 /// XM_006725817 /// XM_006725907 /// XM_006725908 /// XM_006725997 /// XM_006725998 /// XM_006726087 /// XM_006726088 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 201138_s_at BG532929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG532929 /FEA=EST /DB_XREF=gi:13524468 /DB_XREF=est:602580582F1 /CLONE=IMAGE:4718180 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1 BG532929 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_001294145 /// NM_003142 /// XM_005246811 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201139_s_at NM_003142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003142.1 /DEF=Homo sapiens Sjogren syndrome antigen B (autoantigen La) (SSB), mRNA. /FEA=mRNA /GEN=SSB /PROD=autoantigen La /DB_XREF=gi:10835066 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1 NM_003142 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_001294145 /// NM_003142 /// XM_005246811 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201140_s_at NM_004583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004583.1 /DEF=Homo sapiens RAB5C, member RAS oncogene family (RAB5C), mRNA. /FEA=mRNA /GEN=RAB5C /PROD=RAB5C, member RAS oncogene family /DB_XREF=gi:4759019 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1 NM_004583 RAB5C, member RAS oncogene family RAB5C 5878 NM_001252039 /// NM_004583 /// NM_201434 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 201141_at NM_002510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002510.1 /DEF=Homo sapiens glycoprotein (transmembrane) nmb (GPNMB), mRNA. /FEA=mRNA /GEN=GPNMB /PROD=glycoprotein (transmembrane) nmb /DB_XREF=gi:4505404 /UG=Hs.82226 glycoprotein (transmembrane) nmb /FL=gb:AF322909.1 gb:NM_002510.1 NM_002510 glycoprotein (transmembrane) nmb GPNMB 10457 NM_001005340 /// NM_002510 /// XM_005249578 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 201142_at AA577698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA577698 /FEA=EST /DB_XREF=gi:2355882 /DB_XREF=est:nn22h05.s1 /CLONE=IMAGE:1084665 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 AA577698 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201143_s_at BC002513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002513.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ), clone MGC:1511, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:12803384 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 BC002513 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201144_s_at NM_004094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004094.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) (EIF2S1), mRNA. /FEA=mRNA /GEN=EIF2S1 /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:4758255 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 NM_004094 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201145_at NM_006118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006118.2 /DEF=Homo sapiens HS1 binding protein (HAX1), mRNA. /FEA=mRNA /GEN=HAX1 /PROD=HS1 binding protein /DB_XREF=gi:13435355 /UG=Hs.15318 HS1 binding protein /FL=gb:NM_006118.2 gb:BC005240.1 gb:U68566.1 NM_006118 HCLS1 associated protein X-1 HAX1 10456 NM_001018837 /// NM_006118 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030833 // regulation of actin filament polymerization // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019966 // interleukin-1 binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 201146_at NM_006164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006164.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), mRNA. /FEA=mRNA /GEN=NFE2L2 /PROD=nuclear factor (erythroid-derived 2)-like 2 /DB_XREF=gi:5453775 /UG=Hs.155396 nuclear factor (erythroid-derived 2)-like 2 /FL=gb:NM_006164.1 NM_006164 nuclear factor, erythroid 2-like 2 NFE2L2 4780 NM_001145412 /// NM_001145413 /// NM_006164 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 2000121 // regulation of removal of superoxide radicals // inferred from electronic annotation /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201147_s_at BF347089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF347089 /FEA=EST /DB_XREF=gi:11294684 /DB_XREF=est:602020842F1 /CLONE=IMAGE:4156354 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 BF347089 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201148_s_at AW338933 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW338933 /FEA=EST /DB_XREF=gi:6835559 /DB_XREF=est:ha68g07.x1 /CLONE=IMAGE:2878908 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 AW338933 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201149_s_at U67195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U67195.1 /DEF=Human tissue inhibitor of metalloproteinase-3 mRNA, complete cds. /FEA=mRNA /PROD=tissue inhibitor of metalloproteinase-3 /DB_XREF=gi:1519557 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 U67195 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201150_s_at NM_000362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000362.2 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) (TIMP3), mRNA. /FEA=mRNA /GEN=TIMP3 /PROD=tissue inhibitor of metalloproteinase 3precursor /DB_XREF=gi:9257248 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 NM_000362 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201151_s_at BF512200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF512200 /FEA=EST /DB_XREF=gi:11597379 /DB_XREF=est:UI-H-BI3-alq-d-11-0-UI.s1 /CLONE=IMAGE:3068228 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 BF512200 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201152_s_at N31913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N31913 /FEA=EST /DB_XREF=gi:1152312 /DB_XREF=est:yy21f10.s1 /CLONE=IMAGE:271915 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 N31913 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201153_s_at NM_021038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021038.1 /DEF=Homo sapiens muscleblind (Drosophila)-like (MBNL), mRNA. /FEA=mRNA /GEN=MBNL /PROD=muscleblind (Drosophila)-like /DB_XREF=gi:10518339 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 NM_021038 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201154_x_at NM_000968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000968.1 /DEF=Homo sapiens ribosomal protein L4 (RPL4), mRNA. /FEA=mRNA /GEN=RPL4 /PROD=ribosomal protein L4 /DB_XREF=gi:4506652 /UG=Hs.286 ribosomal protein L4 /FL=gb:BC001365.1 gb:L20868.1 gb:D23660.1 gb:NM_000968.1 NM_000968 ribosomal protein L4 /// small nucleolar RNA, C/D box 16 /// small nucleolar RNA, C/D box 18A /// small nucleolar RNA, C/D box 18B /// small nucleolar RNA, C/D box 18C RPL4 /// SNORD16 /// SNORD18A /// SNORD18B /// SNORD18C 6124 /// 595097 /// 595098 /// 595099 /// 595100 NM_000968 /// NR_002440 /// NR_002441 /// NR_002442 /// NR_002443 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201155_s_at NM_014874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014874.1 /DEF=Homo sapiens KIAA0214 gene product (KIAA0214), mRNA. /FEA=mRNA /GEN=KIAA0214 /PROD=KIAA0214 gene product /DB_XREF=gi:7662003 /UG=Hs.3363 KIAA0214 gene product /FL=gb:D86987.1 gb:AF036536.1 gb:NM_014874.1 NM_014874 mitofusin 2 MFN2 9927 NM_001127660 /// NM_014874 /// XM_005263543 /// XM_005263545 /// XM_005263547 /// XM_005263548 0001825 // blastocyst formation // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051646 // mitochondrion localization // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031306 // intrinsic component of mitochondrial outer membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201156_s_at AF141304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF141304.1 /DEF=Homo sapiens small GTPase (RAB5C) mRNA, complete cds. /FEA=CDS /GEN=RAB5C /PROD=small GTPase /DB_XREF=gi:7672664 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1 AF141304 RAB5C, member RAS oncogene family RAB5C 5878 NM_001252039 /// NM_004583 /// NM_201434 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 201157_s_at AF020500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF020500.1 /DEF=Homo sapiens myristoyl CoA:protein N-myristoyltransferase mRNA, complete cds. /FEA=CDS /PROD=myristoyl CoA:protein N-myristoyltransferase /DB_XREF=gi:2760893 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 AF020500 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation 201158_at AI570834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI570834 /FEA=EST /DB_XREF=gi:4534208 /DB_XREF=est:tr67g09.x1 /CLONE=IMAGE:2223424 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 AI570834 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation 201159_s_at NM_021079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021079.1 /DEF=Homo sapiens N-myristoyltransferase 1 (NMT1), mRNA. /FEA=mRNA /GEN=NMT1 /PROD=N-myristoyltransferase 1 /DB_XREF=gi:10835072 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 NM_021079 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation 201160_s_at AL556190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL556190 /FEA=EST /DB_XREF=gi:12898634 /DB_XREF=est:AL556190 /CLONE=CS0DK011YH09 (5 prime) /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1 AL556190 Y box binding protein 3 YBX3 8531 NM_001145426 /// NM_003651 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred by curator /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from mutant phenotype /// 2000767 // positive regulation of cytoplasmic translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201161_s_at NM_003651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003651.1 /DEF=Homo sapiens cold shock domain protein A (CSDA), mRNA. /FEA=mRNA /GEN=CSDA /PROD=cold shock domain protein A /DB_XREF=gi:4503070 /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1 NM_003651 Y box binding protein 3 YBX3 8531 NM_001145426 /// NM_003651 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred by curator /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from mutant phenotype /// 2000767 // positive regulation of cytoplasmic translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201162_at NM_001553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1 NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001253835 /// NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051414 // response to cortisol // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201163_s_at NM_001553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1 NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001253835 /// NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051414 // response to cortisol // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201164_s_at BG474429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG474429 /FEA=EST /DB_XREF=gi:13406706 /DB_XREF=est:602517152F1 /CLONE=IMAGE:4648765 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BG474429 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201165_s_at BE670915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE670915 /FEA=EST /DB_XREF=gi:10031456 /DB_XREF=est:7e43a09.x1 /CLONE=IMAGE:3285208 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BE670915 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201166_s_at NM_014676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014676.1 /DEF=Homo sapiens pumilio (Drosophila) homolog 1 (PUM1), mRNA. /FEA=mRNA /GEN=PUM1 /PROD=pumilio (Drosophila) homolog 1 /DB_XREF=gi:13491165 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 NM_014676 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201167_x_at D13989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13989.1 /DEF=Human rho GDI mRNA, complete cds. /FEA=mRNA /PROD=human rho GDI /DB_XREF=gi:285978 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1 D13989 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201168_x_at NM_004309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004309.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) alpha (ARHGDIA), mRNA. /FEA=mRNA /GEN=ARHGDIA /PROD=Rho GDP dissociation inhibitor (GDI) alpha /DB_XREF=gi:4757767 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1 NM_004309 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201169_s_at BG326045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG326045 /FEA=EST /DB_XREF=gi:13132482 /DB_XREF=est:602424821F1 /CLONE=IMAGE:4562789 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1 BG326045 basic helix-loop-helix family, member e40 BHLHE40 8553 NM_003670 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043426 // MRF binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201170_s_at NM_003670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003670.1 /DEF=Homo sapiens basic helix-loop-helix domain containing, class B, 2 (BHLHB2), mRNA. /FEA=mRNA /GEN=BHLHB2 /PROD=differentiated embryo chondrocyte expressed gene1 /DB_XREF=gi:4503298 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1 NM_003670 basic helix-loop-helix family, member e40 BHLHE40 8553 NM_003670 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043426 // MRF binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201171_at NM_003945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1 NM_003945 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 201172_x_at NM_003945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1 NM_003945 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 201173_x_at NM_006600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006600.1 /DEF=Homo sapiens nuclear distribution gene C (A.nidulans) homolog (NUDC), mRNA. /FEA=mRNA /GEN=NUDC /PROD=nuclear distribution gene C (A.nidulans)homolog /DB_XREF=gi:5729952 /UG=Hs.263812 nuclear distribution gene C (A.nidulans) homolog /FL=gb:BC002399.1 gb:BC003132.1 gb:AB019408.1 gb:AF130736.1 gb:AF125465.1 gb:AF100760.1 gb:NM_006600.1 NM_006600 nudC nuclear distribution protein NUDC 10726 NM_006600 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201174_s_at NM_018975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018975.1 /DEF=Homo sapiens TRF2-interacting telomeric RAP1 protein (RAP1), mRNA. /FEA=mRNA /GEN=RAP1 /PROD=TRF2-interacting telomeric RAP1 protein /DB_XREF=gi:9507032 /UG=Hs.274428 TRF2-interacting telomeric RAP1 protein /FL=gb:BC004465.1 gb:AF262988.1 gb:NM_018975.1 NM_018975 telomeric repeat binding factor 2, interacting protein TERF2IP 54386 NM_018975 0000723 // telomere maintenance // inferred from direct assay /// 0000723 // telomere maintenance // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from sequence or structural similarity /// 0010833 // telomere maintenance via telomere lengthening // inferred from sequence or structural similarity /// 0031848 // protection from non-homologous end joining at telomere // inferred from mutant phenotype /// 0031848 // protection from non-homologous end joining at telomere // inferred from sequence or structural similarity /// 0032205 // negative regulation of telomere maintenance // inferred from direct assay /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0048239 // negative regulation of DNA recombination at telomere // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype 0000228 // nuclear chromosome // traceable author statement /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030870 // Mre11 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // traceable author statement 201175_at NM_015959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015959.1 /DEF=Homo sapiens CGI-31 protein (LOC51075), mRNA. /FEA=mRNA /GEN=LOC51075 /PROD=CGI-31 protein /DB_XREF=gi:7705725 /UG=Hs.279861 CGI-31 protein /FL=gb:AF059753.1 gb:BC000666.1 gb:AF132965.1 gb:NM_015959.1 NM_015959 thioredoxin-related transmembrane protein 2 TMX2 51075 NM_001144012 /// NM_015959 /// NR_026593 /// NR_037645 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201176_s_at NM_001655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001655.2 /DEF=Homo sapiens archain 1 (ARCN1), mRNA. /FEA=mRNA /GEN=ARCN1 /PROD=archain /DB_XREF=gi:11863153 /UG=Hs.33642 archain 1 /FL=gb:NM_001655.2 NM_001655 archain 1 ARCN1 372 NM_001142281 /// NM_001655 /// XM_005271542 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0021691 // cerebellar Purkinje cell layer maturation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201177_s_at NM_005499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005499.1 /DEF=Homo sapiens SUMO-1 activating enzyme subunit 2 (UBA2), mRNA. /FEA=mRNA /GEN=UBA2 /PROD=SUMO-1 activating enzyme subunit 2 /DB_XREF=gi:4885648 /UG=Hs.4311 SUMO-1 activating enzyme subunit 2 /FL=gb:BC003153.1 gb:U35832.1 gb:AF090384.1 gb:AF079566.1 gb:AF110957.1 gb:NM_005499.1 gb:AL136905.1 NM_005499 ubiquitin-like modifier activating enzyme 2 UBA2 10054 NM_005499 /// XM_005258403 /// XM_005258404 /// XM_006722962 0006464 // cellular protein modification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0019950 // SMT3-dependent protein catabolic process // not recorded /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0031510 // SUMO activating enzyme complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019948 // SUMO activating enzyme activity // inferred from direct assay /// 0019948 // SUMO activating enzyme activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201178_at NM_012179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012179.1 /DEF=Homo sapiens F-box only protein 7 (FBXO7), mRNA. /FEA=mRNA /GEN=FBXO7 /PROD=F-box only protein 7 /DB_XREF=gi:7106310 /UG=Hs.5912 F-box only protein 7 /FL=gb:AF129537.1 gb:NM_012179.1 gb:AF233225.1 NM_012179 F-box protein 7 FBXO7 25793 NM_001033024 /// NM_001257990 /// NM_012179 0000422 // mitochondrion degradation // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201179_s_at J03005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03005.1 /DEF=Human alternative guanine nucleotide-binding regulatory protein (G) alpha-inhibitory-subunit mRNA, complete cds. /FEA=mRNA /GEN=GNAI1 /DB_XREF=gi:183183 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 J03005 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201180_s_at J03198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03198.1 /DEF=Human stimulatory G protein (of receptor-regulated K+ channels) alpha subunit mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183224 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 J03198 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201181_at NM_006496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006496.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3), mRNA. /FEA=mRNA /GEN=GNAI3 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 3 /DB_XREF=gi:5729849 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 NM_006496 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201182_s_at AI761771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761771 /FEA=EST /DB_XREF=gi:5177362 /DB_XREF=est:wi62b06.x1 /CLONE=IMAGE:2394803 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI761771 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201183_s_at AI613273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI613273 /FEA=EST /DB_XREF=gi:4622440 /DB_XREF=est:ty35e03.x1 /CLONE=IMAGE:2281084 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI613273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201184_s_at NM_001273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001273.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 4 (CHD4), mRNA. /FEA=mRNA /GEN=CHD4 /PROD=chromodomain helicase DNA binding protein 4 /DB_XREF=gi:4557452 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 NM_001273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201185_at NM_002775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002775.1 /DEF=Homo sapiens protease, serine, 11 (IGF binding) (PRSS11), mRNA. /FEA=mRNA /GEN=PRSS11 /PROD=protease, serine, 11 (IGF binding) /DB_XREF=gi:4506140 /UG=Hs.75111 protease, serine, 11 (IGF binding) /FL=gb:D87258.1 gb:NM_002775.1 NM_002775 HtrA serine peptidase 1 HTRA1 5654 NM_002775 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201186_at NM_002337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002337.1 /DEF=Homo sapiens low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) (LRPAP1), mRNA. /FEA=mRNA /GEN=LRPAP1 /PROD=low density lipoprotein-relatedprotein-associated protein 1 (alpha-2-macroglobulinreceptor-associated protein 1) /DB_XREF=gi:4505020 /UG=Hs.75140 low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) /FL=gb:M63959.1 gb:NM_002337.1 NM_002337 low density lipoprotein receptor-related protein associated protein 1 LRPAP1 4043 NM_002337 /// NR_110005 0006457 // protein folding // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0016192 // vesicle-mediated transport // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 1900116 // extracellular negative regulation of signal transduction // inferred from direct assay /// 1900222 // negative regulation of beta-amyloid clearance // inferred from genetic interaction 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0048237 // rough endoplasmic reticulum lumen // inferred from electronic annotation 0004873 // asialoglycoprotein receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0035473 // lipase binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction 201187_s_at BF001241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001241 /FEA=EST /DB_XREF=gi:10701516 /DB_XREF=est:7g96c02.x1 /CLONE=IMAGE:3314306 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 BF001241 inositol 1,4,5-trisphosphate receptor, type 3 ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity 0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 201188_s_at D26351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D26351.1 /DEF=Human mRNA for type 3 inositol 1,4,5-trisphosphate receptor, complete cds. /FEA=mRNA /PROD=human type 3 inositol 1,4,5-trisphosphatereceptor /DB_XREF=gi:450470 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 D26351 inositol 1,4,5-trisphosphate receptor, type 3 ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity 0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 201189_s_at NM_002224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002224.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 3 (ITPR3), mRNA. /FEA=mRNA /GEN=ITPR3 /PROD=inositol 1,4,5-triphosphate receptor, type 3 /DB_XREF=gi:4504794 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 NM_002224 inositol 1,4,5-trisphosphate receptor, type 3 ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity 0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 201190_s_at H15647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201191_at H15647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201192_s_at NM_006224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006224.1 /DEF=Homo sapiens phosphotidylinositol transfer protein (PITPN), mRNA. /FEA=mRNA /GEN=PITPN /PROD=phosphotidylinositol transfer protein /DB_XREF=gi:5453907 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 NM_006224 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201193_at NM_005896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005896.1 /DEF=Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1), mRNA. /FEA=mRNA /GEN=IDH1 /PROD=isocitrate dehydrogenase 1 (NADP+), soluble /DB_XREF=gi:5174470 /UG=Hs.11223 isocitrate dehydrogenase 1 (NADP+), soluble /FL=gb:AF020038.1 gb:AF113917.1 gb:NM_005896.1 gb:AL136702.1 NM_005896 isocitrate dehydrogenase 1 (NADP+), soluble IDH1 3417 NM_001282386 /// NM_001282387 /// NM_005896 0006097 // glyoxylate cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006102 // isocitrate metabolic process // inferred from direct assay /// 0006103 // 2-oxoglutarate metabolic process // inferred from direct assay /// 0006103 // 2-oxoglutarate metabolic process // traceable author statement /// 0006740 // NADPH regeneration // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0004450 // isocitrate dehydrogenase (NADP+) activity // not recorded /// 0004450 // isocitrate dehydrogenase (NADP+) activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201194_at NM_003009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003009.1 /DEF=Homo sapiens selenoprotein W, 1 (SEPW1), mRNA. /FEA=mRNA /GEN=SEPW1 /PROD=selenoprotein W, 1 /DB_XREF=gi:4506886 /UG=Hs.14231 selenoprotein W, 1 /FL=gb:U67171.1 gb:AF015283.1 gb:NM_003009.1 NM_003009 selenoprotein W, 1 SEPW1 6415 NM_003009 0045454 // cell redox homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008430 // selenium binding // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation 201195_s_at AB018009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB018009.1 /DEF=Homo sapiens mRNA for L-type amino acid transporter 1, complete cds. /FEA=mRNA /GEN=hLAT1 /PROD=L-type amino acid transporter 1 /DB_XREF=gi:5926731 /UG=Hs.184601 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 /FL=gb:AF077866.1 gb:AB018542.1 gb:AF104032.1 gb:NM_003486.1 gb:AB017908.1 gb:AB018009.1 AB018009 solute carrier family 7 (amino acid transporter light chain, L system), member 5 SLC7A5 8140 NM_003486 /// XM_006721286 /// XM_006721287 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 201196_s_at M21154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21154.1 /DEF=Human S-adenosylmethionine decarboxylase mRNA, complete cds. /FEA=mRNA /GEN=AMD2 /DB_XREF=gi:178517 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3 M21154 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001287214 /// NM_001287215 /// NM_001287216 /// NM_001634 /// NR_109768 0006557 // S-adenosylmethioninamine biosynthetic process // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201197_at NM_001634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001634.3 /DEF=Homo sapiens S-adenosylmethionine decarboxylase 1 (AMD1), mRNA. /FEA=mRNA /GEN=AMD1 /PROD=S-adenosylmethionine decarboxylase 1 precursor /DB_XREF=gi:5209326 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3 NM_001634 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001287214 /// NM_001287215 /// NM_001287216 /// NM_001634 /// NR_109768 0006557 // S-adenosylmethioninamine biosynthetic process // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201198_s_at AI860431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI860431 /FEA=EST /DB_XREF=gi:5514047 /DB_XREF=est:wl13h07.x1 /CLONE=IMAGE:2424829 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1 AI860431 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 PSMD1 5707 NM_001191037 /// NM_002807 /// NR_034059 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201199_s_at NM_002807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002807.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 (PSMD1), mRNA. /FEA=mRNA /GEN=PSMD1 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 1 /DB_XREF=gi:4506224 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1 NM_002807 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 PSMD1 5707 NM_001191037 /// NM_002807 /// NR_034059 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201200_at NM_003851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003851.1 /DEF=Homo sapiens cellular repressor of E1A-stimulated genes (CREG), mRNA. /FEA=mRNA /GEN=CREG /PROD=cellular repressor of E1A-stimulated genes /DB_XREF=gi:4503036 /UG=Hs.5710 cellular repressor of E1A-stimulated genes /FL=gb:AF084523.1 gb:NM_003851.1 NM_003851 cellular repressor of E1A-stimulated genes 1 CREG1 8804 NM_003851 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201201_at NM_000100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000100.1 /DEF=Homo sapiens cystatin B (stefin B) (CSTB), mRNA. /FEA=mRNA /GEN=CSTB /PROD=cystatin B (stefin B) /DB_XREF=gi:4503116 /UG=Hs.695 cystatin B (stefin B) /FL=gb:BC003370.1 gb:L03558.1 gb:NM_000100.1 NM_000100 cystatin B (stefin B) CSTB 1476 NM_000100 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201202_at NM_002592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002592.1 /DEF=Homo sapiens proliferating cell nuclear antigen (PCNA), mRNA. /FEA=mRNA /GEN=PCNA /PROD=proliferating cell nuclear antigen /DB_XREF=gi:4505640 /UG=Hs.78996 proliferating cell nuclear antigen /FL=gb:BC000491.1 gb:M15796.1 gb:NM_002592.1 NM_002592 proliferating cell nuclear antigen PCNA 5111 NM_002592 /// NM_182649 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006272 // leading strand elongation // not recorded /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0019985 // translesion synthesis // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032077 // positive regulation of deoxyribonuclease activity // inferred from direct assay /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0033993 // response to lipid // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay /// 0043626 // PCNA complex // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070557 // PCNA-p21 complex // inferred from direct assay 0000701 // purine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030337 // DNA polymerase processivity factor activity // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0032139 // dinucleotide insertion or deletion binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0070182 // DNA polymerase binding // inferred from physical interaction 201203_s_at AI921320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI921320 /FEA=EST /DB_XREF=gi:5657284 /DB_XREF=est:wo23c10.x1 /CLONE=IMAGE:2456178 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AI921320 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201204_s_at AA706065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA706065 /FEA=EST /DB_XREF=gi:2715983 /DB_XREF=est:zf44f12.s1 /CLONE=IMAGE:379823 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AA706065 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201205_at AF006751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF006751.1 /DEF=Homo sapiens ES130 mRNA, complete cds. /FEA=mRNA /PROD=ES130 /DB_XREF=gi:3299884 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AF006751 201206_s_at NM_004587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004587.1 /DEF=Homo sapiens ribosome binding protein 1 (dog 180kD homolog) (RRBP1), mRNA. /FEA=mRNA /GEN=RRBP1 /PROD=ribosome binding protein 1 /DB_XREF=gi:4759055 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 NM_004587 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201207_at NM_021137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021137.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 1 (endothelial) (TNFAIP1), mRNA. /FEA=mRNA /GEN=TNFAIP1 /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:10863936 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1 NM_021137 tumor necrosis factor, alpha-induced protein 1 (endothelial) TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from expression pattern /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 201208_s_at BC001643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001643.1 /DEF=Homo sapiens, tumor necrosis factor, alpha-induced protein 1 (endothelial), clone MGC:2317, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:12804470 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1 BC001643 tumor necrosis factor, alpha-induced protein 1 (endothelial) TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from expression pattern /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 201209_at NM_004964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004964.2 /DEF=Homo sapiens histone deacetylase 1 (HDAC1), mRNA. /FEA=mRNA /GEN=HDAC1 /PROD=histone deacetylase 1 /DB_XREF=gi:13128859 /UG=Hs.88556 histone deacetylase 1 /FL=gb:BC000301.1 gb:U50079.1 gb:NM_004964.2 gb:D50405.1 NM_004964 histone deacetylase 1 HDAC1 3065 NM_004964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006338 // chromatin remodeling // inferred by curator /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009913 // epidermal cell differentiation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043922 // negative regulation by host of viral transcription // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061198 // fungiform papilla formation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay 0000118 // histone deacetylase complex // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0004407 // histone deacetylase activity // inferred from mutant phenotype /// 0004407 // histone deacetylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0033558 // protein deacetylase activity // inferred from mutant phenotype /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 201210_at NM_001356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001356.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 (DDX3), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDX3 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /DB_XREF=gi:13514812 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1 NM_001356 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 201211_s_at AF061337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061337.1 /DEF=Homo sapiens DEAD box RNA helicase DDX3 (DDX3) mRNA, complete cds. /FEA=mRNA /GEN=DDX3 /PROD=DEAD box RNA helicase DDX3 /DB_XREF=gi:3523149 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1 AF061337 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 201212_at D55696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D55696.1 /DEF=Homo sapiens mRNA for cysteine protease, complete cds. /FEA=mRNA /PROD=cysteine protease /DB_XREF=gi:1890049 /UG=Hs.18069 protease, cysteine, 1 (legumain) /FL=gb:BC003061.1 gb:D55696.1 gb:NM_005606.1 D55696 legumain LGMN 5641 NM_001008530 /// NM_005606 /// XM_005267862 /// XM_005267863 0001101 // response to acid // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0003014 // renal system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0008202 // steroid metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032801 // receptor catabolic process // inferred from sequence or structural similarity /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 1901185 // negative regulation of ERBB signaling pathway // inferred from sequence or structural similarity 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201213_at AI090331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI090331 /FEA=EST /DB_XREF=gi:3429390 /DB_XREF=est:oy81f08.s1 /CLONE=IMAGE:1672263 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1 AI090331 protein phosphatase 1, regulatory subunit 7 PPP1R7 5510 NM_001282409 /// NM_001282410 /// NM_001282411 /// NM_001282412 /// NM_001282413 /// NM_001282414 /// NM_002712 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201214_s_at NM_002712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002712.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 7 (PPP1R7), mRNA. /FEA=mRNA /GEN=PPP1R7 /PROD=protein phosphatase 1, regulatory subunit 7 /DB_XREF=gi:4506012 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1 NM_002712 protein phosphatase 1, regulatory subunit 7 PPP1R7 5510 NM_001282409 /// NM_001282410 /// NM_001282411 /// NM_001282412 /// NM_001282413 /// NM_001282414 /// NM_002712 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201215_at NM_005032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005032.2 /DEF=Homo sapiens plastin 3 (T isoform) (PLS3), mRNA. /FEA=mRNA /GEN=PLS3 /PROD=plastin 3 precursor /DB_XREF=gi:7549808 /UG=Hs.4114 plastin 3 (T isoform) /FL=gb:M22299.1 gb:NM_005032.2 NM_005032 plastin 3 PLS3 5358 NM_001136025 /// NM_001172335 /// NM_001282337 /// NM_001282338 /// NM_005032 0060348 // bone development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201216_at NM_006817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006817.2 /DEF=Homo sapiens endoplasmic reticulum lumenal protein (ERP28), mRNA. /FEA=mRNA /GEN=ERP28 /PROD=endoplasmic reticulum lumenal protein ERp28precursor /DB_XREF=gi:13124889 /UG=Hs.75841 endoplasmic reticulum lumenal protein /FL=gb:NM_006817.2 NM_006817 endoplasmic reticulum protein 29 ERP29 10961 NM_001034025 /// NM_006817 0006457 // protein folding // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0009306 // protein secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201217_x_at NM_000967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000967.1 /DEF=Homo sapiens ribosomal protein L3 (RPL3), mRNA. /FEA=mRNA /GEN=RPL3 /PROD=ribosomal protein L3 /DB_XREF=gi:4506648 /UG=Hs.119598 ribosomal protein L3 /FL=gb:BC002408.1 gb:BC004323.1 gb:NM_000967.1 NM_000967 RNA, U86 small nucleolar /// ribosomal protein L3 /// small nucleolar RNA, C/D box 83B RNU86 /// RPL3 /// SNORD83B 6122 /// 116936 /// 116938 NM_000967 /// NM_001033853 /// NR_000026 /// NR_000028 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201218_at N23018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N23018 /FEA=EST /DB_XREF=gi:1137168 /DB_XREF=est:yx65d12.s1 /CLONE=IMAGE:266615 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 N23018 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201219_at AW269836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW269836 /FEA=EST /DB_XREF=gi:6656866 /DB_XREF=est:xv45h03.x1 /CLONE=IMAGE:2816117 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 AW269836 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201220_x_at NM_001329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001329.1 /DEF=Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=CTBP2 /PROD=C-terminal binding protein 2, isoform 1 /DB_XREF=gi:4557498 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 NM_001329 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201221_s_at NM_003089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003089.1 /DEF=Homo sapiens small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) (SNRP70), mRNA. /FEA=mRNA /GEN=SNRP70 /PROD=small nuclear ribonucleoprotein 70kD polypeptide(RNP antigen) /DB_XREF=gi:4507118 /UG=Hs.174051 small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) /FL=gb:BC000342.1 gb:M22636.1 gb:NM_003089.1 NM_003089 small nuclear ribonucleoprotein 70kDa (U1) SNRNP70 6625 NM_001009820 /// NM_003089 /// XM_005259177 /// XM_005259178 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032608 // interferon-beta production // inferred from electronic annotation /// 0032608 // interferon-beta production // inferred from sequence or structural similarity /// 0034340 // response to type I interferon // inferred from electronic annotation /// 0034340 // response to type I interferon // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201222_s_at AL527365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL527365 /FEA=EST /DB_XREF=gi:12790858 /DB_XREF=est:AL527365 /CLONE=CS0DC021YG08 (5 prime) /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1 AL527365 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_001244713 /// NM_001244724 /// NM_002874 0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 201223_s_at NM_002874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002874.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog B (RAD23B), mRNA. /FEA=mRNA /GEN=RAD23B /PROD=RAD23 (S. cerevisiae) homolog B /DB_XREF=gi:4506386 /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1 NM_002874 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_001244713 /// NM_001244724 /// NM_002874 0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 201224_s_at AU147713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147713 /FEA=EST /DB_XREF=gi:11009234 /DB_XREF=est:AU147713 /CLONE=MAMMA1001474 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1 AU147713 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 /// XM_005245717 /// XM_005245718 /// XM_005245719 /// XM_005245720 /// XM_005245721 /// XM_005245722 /// XR_241182 /// XR_241183 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201225_s_at NM_005839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005839.1 /DEF=Homo sapiens SerArg-related nuclear matrix protein (plenty of prolines 101-like) (SRM160), mRNA. /FEA=mRNA /GEN=SRM160 /PROD=SerArg-related nuclear matrix protein (plentyof prolines 101-like) /DB_XREF=gi:5032118 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1 NM_005839 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 /// XM_005245717 /// XM_005245718 /// XM_005245719 /// XM_005245720 /// XM_005245721 /// XM_005245722 /// XR_241182 /// XR_241183 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201226_at NM_005004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1 NM_005004 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa NDUFB8 4714 NM_001284367 /// NM_001284368 /// NM_005004 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201227_s_at NM_005004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1 NM_005004 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa NDUFB8 4714 NM_001284367 /// NM_001284368 /// NM_005004 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201228_s_at AW074830 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW074830 /FEA=EST /DB_XREF=gi:6029828 /DB_XREF=est:xa08a08.x1 /CLONE=IMAGE:2567702 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 AW074830 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201229_s_at BC000422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000422.1 /DEF=Homo sapiens, ariadne (Drosophila) homolog 2, clone MGC:8671, mRNA, complete cds. /FEA=mRNA /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:12653306 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 BC000422 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201230_s_at NM_006321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006321.1 /DEF=Homo sapiens ariadne (Drosophila) homolog 2 (ARIH2), mRNA. /FEA=mRNA /GEN=ARIH2 /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:5453556 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 NM_006321 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201231_s_at NM_001428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001428.1 /DEF=Homo sapiens enolase 1, (alpha) (ENO1), mRNA. /FEA=mRNA /GEN=ENO1 /PROD=enolase 1, (alpha) /DB_XREF=gi:4503570 /UG=Hs.254105 enolase 1, (alpha) /FL=gb:BC001810.1 gb:BC004458.1 gb:M14328.1 gb:NM_001428.1 NM_001428 enolase 1, (alpha) ENO1 2023 NM_001201483 /// NM_001428 /// XM_006710433 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201232_s_at NM_002817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1 NM_002817 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 PSMD13 5719 NM_002817 /// NM_175932 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201233_at NM_002817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1 NM_002817 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 PSMD13 5719 NM_002817 /// NM_175932 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201234_at NM_004517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004517.1 /DEF=Homo sapiens integrin-linked kinase (ILK), mRNA. /FEA=mRNA /GEN=ILK /PROD=integrin-linked kinase /DB_XREF=gi:4758605 /UG=Hs.6196 integrin-linked kinase /FL=gb:U40282.1 gb:NM_004517.1 NM_004517 integrin-linked kinase ILK 3611 NM_001014794 /// NM_001014795 /// NM_001278441 /// NM_001278442 /// NM_004517 /// XM_005252904 /// XM_005252905 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 201235_s_at BG339064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG339064 /FEA=EST /DB_XREF=gi:13145502 /DB_XREF=est:602436889F1 /CLONE=IMAGE:4554551 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1 BG339064 BTG family, member 2 BTG2 7832 NM_006763 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008306 // associative learning // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201236_s_at NM_006763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006763.1 /DEF=Homo sapiens BTG family, member 2 (BTG2), mRNA. /FEA=mRNA /GEN=BTG2 /PROD=BTG family, member 2 /DB_XREF=gi:5802987 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1 NM_006763 BTG family, member 2 BTG2 7832 NM_006763 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008306 // associative learning // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201237_at AV685920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV685920 /FEA=EST /DB_XREF=gi:10287783 /DB_XREF=est:AV685920 /CLONE=GKCEGD05 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1 AV685920 capping protein (actin filament) muscle Z-line, alpha 2 CAPZA2 830 NM_006136 0006461 // protein complex assembly // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201238_s_at BC005338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005338.1 /DEF=Homo sapiens, capping protein (actin filament) muscle Z-line, alpha 2, clone MGC:12426, mRNA, complete cds. /FEA=mRNA /PROD=capping protein (actin filament) muscle Z-line,alpha 2 /DB_XREF=gi:13529130 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1 BC005338 capping protein (actin filament) muscle Z-line, alpha 2 CAPZA2 830 NM_006136 0006461 // protein complex assembly // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201239_s_at BF530535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF530535 /FEA=EST /DB_XREF=gi:11617898 /DB_XREF=est:602071788F1 /CLONE=IMAGE:4214660 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1 BF530535 signal peptidase complex subunit 2 homolog (S. cerevisiae) SPCS2 9789 NM_014752 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201240_s_at NM_014752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014752.1 /DEF=Homo sapiens KIAA0102 gene product (KIAA0102), mRNA. /FEA=mRNA /GEN=KIAA0102 /PROD=KIAA0102 gene product /DB_XREF=gi:7661907 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1 NM_014752 signal peptidase complex subunit 2 homolog (S. cerevisiae) SPCS2 9789 NM_014752 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201241_at NM_004939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004939.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 (DDX1), mRNA. /FEA=mRNA /GEN=DDX1 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /DB_XREF=gi:4826685 /UG=Hs.78580 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /FL=gb:X70649.1 gb:NM_004939.1 NM_004939 DEAD (Asp-Glu-Ala-Asp) box helicase 1 DDX1 1653 NM_004939 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from expression pattern /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0071920 // cleavage body // inferred from direct assay /// 0072669 // tRNA-splicing ligase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033677 // DNA/RNA helicase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201242_s_at BC000006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000006.1 /DEF=Homo sapiens, ATPase, Na+K+ transporting, beta 1 polypeptide, clone MGC:1798, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:12652534 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1 BC000006 ATPase, Na+/K+ transporting, beta 1 polypeptide ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 201243_s_at NM_001677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001677.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, beta 1 polypeptide (ATP1B1), mRNA. /FEA=mRNA /GEN=ATP1B1 /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:4502276 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1 NM_001677 ATPase, Na+/K+ transporting, beta 1 polypeptide ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 201244_s_at NM_002880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002880.1 /DEF=Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1), mRNA. /FEA=mRNA /GEN=RAF1 /PROD=v-raf-1 murine leukemia viral oncogene homolog1 /DB_XREF=gi:4506400 /UG=Hs.85181 v-raf-1 murine leukemia viral oncogene homolog 1 /FL=gb:NM_002880.1 NM_002880 Raf-1 proto-oncogene, serine/threonine kinase RAF1 5894 NM_002880 /// XM_005265355 /// XM_005265357 /// XM_005265358 /// XM_005265359 /// XM_005265360 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071550 // death-inducing signaling complex assembly // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from physical interaction /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201245_s_at AL523776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523776 /FEA=EST /DB_XREF=gi:12787269 /DB_XREF=est:AL523776 /CLONE=CS0DC003YC23 (5 prime) /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1 AL523776 uncharacterized LOC101927673 /// OTU deubiquitinase, ubiquitin aldehyde binding 1 LOC101927673 /// OTUB1 55611 /// 101927673 NM_017670 /// NR_003089 /// XR_247234 /// XR_247664 /// XR_252904 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from direct assay /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201246_s_at NM_017670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017670.1 /DEF=Homo sapiens hypothetical protein FLJ20113 (FLJ20113), mRNA. /FEA=mRNA /GEN=FLJ20113 /PROD=hypothetical protein FLJ20113 /DB_XREF=gi:8923113 /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1 NM_017670 uncharacterized LOC101927673 /// OTU deubiquitinase, ubiquitin aldehyde binding 1 LOC101927673 /// OTUB1 55611 /// 101927673 NM_017670 /// NR_003089 /// XR_247234 /// XR_247664 /// XR_252904 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from direct assay /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201247_at BE513151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE513151 /FEA=EST /DB_XREF=gi:9720362 /DB_XREF=est:601171940F1 /CLONE=IMAGE:3545697 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1 BE513151 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 /// NR_103834 /// XM_006724310 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0071499 // cellular response to laminar fluid shear stress // non-traceable author statement /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0000247 // C-8 sterol isomerase activity // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201248_s_at NM_004599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004599.1 /DEF=Homo sapiens sterol regulatory element binding transcription factor 2 (SREBF2), mRNA. /FEA=mRNA /GEN=SREBF2 /PROD=sterol regulatory element binding transcriptionfactor 2 /DB_XREF=gi:4759169 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1 NM_004599 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 /// NR_103834 /// XM_006724310 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0071499 // cellular response to laminar fluid shear stress // non-traceable author statement /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0000247 // C-8 sterol isomerase activity // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201249_at AI091047 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI091047 /FEA=EST /DB_XREF=gi:3430106 /DB_XREF=est:qa53b03.s1 /CLONE=IMAGE:1690445 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1 AI091047 solute carrier family 2 (facilitated glucose transporter), member 1 SLC2A1 6513 NM_006516 0005975 // carbohydrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070837 // dehydroascorbic acid transport // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0033300 // dehydroascorbic acid transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042910 // xenobiotic transporter activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 201250_s_at NM_006516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006516.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1), mRNA. /FEA=mRNA /GEN=SLC2A1 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 1 /DB_XREF=gi:5730050 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1 NM_006516 solute carrier family 2 (facilitated glucose transporter), member 1 SLC2A1 6513 NM_006516 0005975 // carbohydrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070837 // dehydroascorbic acid transport // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0033300 // dehydroascorbic acid transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042910 // xenobiotic transporter activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 201251_at NM_002654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002654.1 /DEF=Homo sapiens pyruvate kinase, muscle (PKM2), mRNA. /FEA=mRNA /GEN=PKM2 /PROD=pyruvate kinase, muscle /DB_XREF=gi:4505838 /UG=Hs.198281 pyruvate kinase, muscle /FL=gb:BC000481.1 gb:M23725.1 gb:M26252.1 gb:NM_002654.1 NM_002654 pyruvate kinase, muscle PKM 5315 NM_001206796 /// NM_001206797 /// NM_001206798 /// NM_001206799 /// NM_002654 /// NM_182470 /// NM_182471 /// XM_005254443 /// XM_005254445 /// XM_006720570 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201252_at NM_006503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006503.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), mRNA. /FEA=mRNA /GEN=PSMC4 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 4 /DB_XREF=gi:5729990 /UG=Hs.211594 proteasome (prosome, macropain) 26S subunit, ATPase, 4 /FL=gb:BC000343.1 gb:AF038965.1 gb:AF020736.1 gb:U27515.1 gb:NM_006503.1 NM_006503 proteasome (prosome, macropain) 26S subunit, ATPase, 4 PSMC4 5704 NM_006503 /// NM_153001 /// XR_430205 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201253_s_at NM_006319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006319.1 /DEF=Homo sapiens CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) (CDIPT), mRNA. /FEA=mRNA /GEN=CDIPT /PROD=CDP-diacylglycerol--inositol3-phosphatidyltransferase (phosphatidylinositol synthase) /DB_XREF=gi:5453905 /UG=Hs.227107 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) /FL=gb:BC001444.1 gb:AF014807.1 gb:NM_006319.1 NM_006319 CDP-diacylglycerol--inositol 3-phosphatidyltransferase CDIPT 10423 NM_001286585 /// NM_001286586 /// NM_006319 /// NM_145752 /// XM_005255038 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046341 // CDP-diacylglycerol metabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0003881 // CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity // inferred from direct assay /// 0003881 // CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043178 // alcohol binding // inferred from electronic annotation 201254_x_at NM_001010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001010.1 /DEF=Homo sapiens ribosomal protein S6 (RPS6), mRNA. /FEA=mRNA /GEN=RPS6 /PROD=ribosomal protein S6 /DB_XREF=gi:4506730 /UG=Hs.241507 ribosomal protein S6 /FL=gb:M20020.1 gb:NM_001010.1 NM_001010 ribosomal protein S6 RPS6 6194 NM_001010 0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201255_x_at NM_004639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004639.1 /DEF=Homo sapiens HLA-B associated transcript-3 (D6S52E), mRNA. /FEA=mRNA /GEN=D6S52E /PROD=HLA-B associated transcript-3 /DB_XREF=gi:4758109 /UG=Hs.274348 HLA-B associated transcript-3 /FL=gb:M33519.1 gb:NM_004639.1 NM_004639 BCL2-associated athanogene 6 BAG6 7917 NM_001098534 /// NM_001199697 /// NM_001199698 /// NM_004639 /// NM_080702 /// NM_080703 /// XM_005249393 /// XM_005249396 /// XM_005272880 /// XM_005272883 /// XM_005275034 /// XM_005275037 /// XM_005275169 /// XM_005275172 /// XM_005275292 /// XM_005275295 /// XM_005275464 /// XM_005275468 /// XM_005275597 /// XM_005275601 /// XM_006715192 /// XM_006715193 /// XM_006715194 /// XM_006715195 /// XM_006715196 /// XM_006715197 /// XM_006715198 /// XM_006715199 /// XM_006715200 /// XM_006715201 /// XM_006715202 /// XM_006715203 /// XM_006725509 /// XM_006725510 /// XM_006725511 /// XM_006725512 /// XM_006725513 /// XM_006725514 /// XM_006725515 /// XM_006725516 /// XM_006725517 /// XM_006725518 /// XM_006725519 /// XM_006725520 /// XM_006725725 /// XM_006725726 /// XM_006725727 /// XM_006725728 /// XM_006725729 /// XM_006725730 /// XM_006725731 /// XM_006725732 /// XM_006725733 /// XM_006725734 /// XM_006725735 /// XM_006725736 /// XM_006725835 /// XM_006725836 /// XM_006725837 /// XM_006725838 /// XM_006725839 /// XM_006725840 /// XM_006725841 /// XM_006725842 /// XM_006725843 /// XM_006725844 /// XM_006725845 /// XM_006725846 /// XM_006725923 /// XM_006725924 /// XM_006725925 /// XM_006725926 /// XM_006725927 /// XM_006725928 /// XM_006725929 /// XM_006725930 /// XM_006725931 /// XM_006725932 /// XM_006725933 /// XM_006725934 /// XM_006726025 /// XM_006726026 /// XM_006726027 /// XM_006726028 /// XM_006726029 /// XM_006726030 /// XM_006726031 /// XM_006726032 /// XM_006726033 /// XM_006726034 /// XM_006726035 /// XM_006726036 /// XM_006726113 /// XM_006726114 /// XM_006726115 /// XM_006726116 /// XM_006726117 /// XM_006726118 /// XM_006726119 /// XM_006726120 /// XM_006726121 /// XM_006726122 /// XM_006726123 /// XM_006726124 0001822 // kidney development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from sequence or structural similarity /// 0043022 // ribosome binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from sequence or structural similarity 201256_at NM_004718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004718.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), mRNA. /FEA=mRNA /GEN=COX7A2L /PROD=cytochrome c oxidase subunit VIIa polypeptide 2like /DB_XREF=gi:4758041 /UG=Hs.30888 cytochrome c oxidase subunit VIIa polypeptide 2 like /FL=gb:BC005251.1 gb:AB007618.1 gb:NM_004718.1 NM_004718 cytochrome c oxidase subunit VIIa polypeptide 2 like COX7A2L 9167 NM_004718 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201257_x_at NM_001006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001006.1 /DEF=Homo sapiens ribosomal protein S3A (RPS3A), mRNA. /FEA=mRNA /GEN=RPS3A /PROD=ribosomal protein S3A /DB_XREF=gi:4506722 /UG=Hs.77039 ribosomal protein S3A /FL=gb:BC000204.1 gb:BC001708.1 gb:BC004981.1 gb:M84711.1 gb:M77234.1 gb:L13802.1 gb:NM_001006.1 NM_001006 ribosomal protein S3A /// small nucleolar RNA, C/D box 73A RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201258_at NM_001020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001020.1 /DEF=Homo sapiens ribosomal protein S16 (RPS16), mRNA. /FEA=mRNA /GEN=RPS16 /PROD=ribosomal protein S16 /DB_XREF=gi:4506690 /UG=Hs.80617 ribosomal protein S16 /FL=gb:BC004324.1 gb:M60854.1 gb:NM_001020.1 NM_001020 ribosomal protein S16 RPS16 6217 NM_001020 /// XM_005259137 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201259_s_at AI768845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768845 /FEA=EST /DB_XREF=gi:5235354 /DB_XREF=est:wj12e10.x1 /CLONE=IMAGE:2402634 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1 AI768845 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 /// XM_006716099 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // not recorded /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 201260_s_at NM_006754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006754.1 /DEF=Homo sapiens synaptophysin-like protein (SYPL), mRNA. /FEA=mRNA /GEN=SYPL /PROD=synaptophysin-like protein /DB_XREF=gi:5803184 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1 NM_006754 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 /// XM_006716099 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // not recorded /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 201261_x_at BC002416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002416.1 /DEF=Homo sapiens, biglycan, clone MGC:2298, mRNA, complete cds. /FEA=mRNA /PROD=biglycan /DB_XREF=gi:12803216 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1 BC002416 biglycan BGN 633 NM_001711 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201262_s_at NM_001711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001711.1 /DEF=Homo sapiens biglycan (BGN), mRNA. /FEA=mRNA /GEN=BGN /PROD=biglycan /DB_XREF=gi:4502402 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1 NM_001711 biglycan BGN 633 NM_001711 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201263_at NM_003191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003191.1 /DEF=Homo sapiens threonyl-tRNA synthetase (TARS), mRNA. /FEA=mRNA /GEN=TARS /PROD=threonyl-tRNA synthetase /DB_XREF=gi:4507366 /UG=Hs.84131 threonyl-tRNA synthetase /FL=gb:BC000517.1 gb:M63180.1 gb:NM_003191.1 NM_003191 threonyl-tRNA synthetase TARS 6897 NM_001258437 /// NM_001258438 /// NM_152295 /// NR_047676 /// NR_047677 /// NR_047678 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006435 // threonyl-tRNA aminoacylation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004829 // threonine-tRNA ligase activity // non-traceable author statement /// 0004829 // threonine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement 201264_at NM_007263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007263.1 /DEF=Homo sapiens coatomer protein complex, subunit epsilon (COPE), mRNA. /FEA=mRNA /GEN=COPE /PROD=coatomer protein complex, subunit epsilon /DB_XREF=gi:6005734 /UG=Hs.10326 coatomer protein complex, subunit epsilon /FL=gb:AL136928.1 gb:BC003155.1 gb:NM_007263.1 NM_007263 coatomer protein complex, subunit epsilon COPE 11316 NM_007263 /// NM_199442 /// NM_199444 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 201265_at AF119897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119897.1 /DEF=Homo sapiens PRO2760 mRNA, complete cds. /FEA=mRNA /PROD=PRO2760 /DB_XREF=gi:7770230 /UG=Hs.111334 ferritin, light polypeptide /FL=gb:BC004245.1 gb:M11147.1 gb:M10119.1 gb:NM_000146.1 gb:AF119897.1 AF119897 201266_at NM_003330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003330.1 /DEF=Homo sapiens thioredoxin reductase 1 (TXNRD1), mRNA. /FEA=mRNA /GEN=TXNRD1 /PROD=thioredoxin reductase 1 /DB_XREF=gi:4507746 /UG=Hs.13046 thioredoxin reductase 1 /FL=gb:D88687.1 gb:AF077367.1 gb:NM_003330.1 gb:AF208018.1 NM_003330 thioredoxin reductase 1 TXNRD1 7296 NM_001093771 /// NM_001261445 /// NM_001261446 /// NM_003330 /// NM_182729 /// NM_182742 /// NM_182743 0001707 // mesoderm formation // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006790 // sulfur compound metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016259 // selenocysteine metabolic process // inferred from electronic annotation /// 0042191 // methylmercury metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042537 // benzene-containing compound metabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070276 // halogen metabolic process // inferred from electronic annotation /// 0070995 // NADPH oxidation // inferred from electronic annotation /// 0071280 // cellular response to copper ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0004791 // thioredoxin-disulfide reductase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016174 // NAD(P)H oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0033797 // selenate reductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045340 // mercury ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 201267_s_at AL545523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL545523 /FEA=EST /DB_XREF=gi:12878005 /DB_XREF=est:AL545523 /CLONE=CS0DI015YE19 (5 prime) /UG=Hs.250758 proteasome (prosome, macropain) 26S subunit, ATPase, 3 /FL=gb:M34079.1 gb:NM_002804.1 AL545523 proteasome (prosome, macropain) 26S subunit, ATPase, 3 PSMC3 5702 NM_002804 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201268_at NM_002512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002512.1 /DEF=Homo sapiens non-metastatic cells 2, protein (NM23B) expressed in (NME2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NME2 /PROD=non-metastatic cells 2, protein (NM23B)expressed in /DB_XREF=gi:4505408 /UG=Hs.275163 non-metastatic cells 2, protein (NM23B) expressed in /FL=gb:BC002476.1 gb:M36981.1 gb:L16785.1 gb:NM_002512.1 NM_002512 NME1-NME2 readthrough /// NME/NM23 nucleoside diphosphate kinase 2 NME1-NME2 /// NME2 4831 /// 654364 NM_001018136 /// NM_001018137 /// NM_001018138 /// NM_001018139 /// NM_001198682 /// NM_002512 /// NR_037149 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006308 // DNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018106 // peptidyl-histidine phosphorylation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004673 // protein histidine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0043024 // ribosomal small subunit binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201269_s_at AB028991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028991.1 /DEF=Homo sapiens mRNA for KIAA1068 protein, partial cds. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:5689472 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1 AB028991 NudC domain containing 3 NUDCD3 23386 NM_015332 201270_x_at NM_015332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015332.1 /DEF=Homo sapiens KIAA1068 protein (KIAA1068), mRNA. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:13357209 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1 NM_015332 NudC domain containing 3 NUDCD3 23386 NM_015332 201271_s_at NM_016732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016732.1 /DEF=Homo sapiens RNA-binding protein (autoantigenic) (RALY), transcript variant 1, mRNA. /FEA=mRNA /GEN=RALY /PROD=RNA-binding protein (autoantigenic) longisoform /DB_XREF=gi:8051630 /UG=Hs.74111 RNA-binding protein (autoantigenic) /FL=gb:AF148457.1 gb:NM_016732.1 NM_016732 RALY heterogeneous nuclear ribonucleoprotein RALY 22913 NM_007367 /// NM_016732 /// XM_005260334 /// XM_005260336 /// XM_006723742 /// XM_006723743 /// XM_006723744 /// XM_006723745 /// XM_006723746 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201272_at NM_001628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001628.1 /DEF=Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), mRNA. /FEA=mRNA /GEN=AKR1B1 /PROD=aldo-keto reductase family 1, member B1 (aldosereductase) /DB_XREF=gi:4502048 /UG=Hs.75313 aldo-keto reductase family 1, member B1 (aldose reductase) /FL=gb:BC000260.1 gb:BC005387.1 gb:J04795.1 gb:J05017.1 gb:J05474.1 gb:M34720.1 gb:NM_001628.1 NM_001628 aldo-keto reductase family 1, member B1 (aldose reductase) AKR1B1 231 NM_001628 /// XM_005250234 0005975 // carbohydrate metabolic process // traceable author statement /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from electronic annotation /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043795 // glyceraldehyde oxidoreductase activity // inferred from direct assay 201273_s_at NM_003133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003133.1 /DEF=Homo sapiens signal recognition particle 9kD (SRP9), mRNA. /FEA=mRNA /GEN=SRP9 /PROD=signal recognition particle 9kD /DB_XREF=gi:4507216 /UG=Hs.75975 signal recognition particle 9kD /FL=gb:NM_003133.1 gb:U20998.1 NM_003133 signal recognition particle 9kDa SRP9 6726 NM_001130440 /// NM_003133 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045900 // negative regulation of translational elongation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005785 // signal recognition particle receptor complex // traceable author statement /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005047 // signal recognition particle binding // traceable author statement /// 0008312 // 7S RNA binding // inferred from electronic annotation 201274_at NM_002790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002790.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 5 (PSMA5), mRNA. /FEA=mRNA /GEN=PSMA5 /PROD=proteasome (prosome, macropain) subunit, alphatype, 5 /DB_XREF=gi:4506186 /UG=Hs.76913 proteasome (prosome, macropain) subunit, alpha type, 5 /FL=gb:NM_002790.1 NM_002790 proteasome (prosome, macropain) subunit, alpha type, 5 PSMA5 5686 NM_001199772 /// NM_001199773 /// NM_001199774 /// NM_002790 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201275_at NM_002004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002004.1 /DEF=Homo sapiens farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) (FDPS), mRNA. /FEA=mRNA /GEN=FDPS /PROD=farnesyl diphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase,geranyltranstransferase) /DB_XREF=gi:4503684 /UG=Hs.77393 farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) /FL=gb:J05262.1 gb:D14697.1 gb:NM_002004.1 NM_002004 farnesyl diphosphate synthase FDPS 2224 NM_001135821 /// NM_001135822 /// NM_001242824 /// NM_001242825 /// NM_002004 /// XM_005244962 /// XM_005244963 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201276_at AF267863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF267863.1 /DEF=Homo sapiens DC43 mRNA, complete cds. /FEA=mRNA /PROD=DC43 /DB_XREF=gi:12006052 /UG=Hs.77690 RAB5B, member RAS oncogene family /FL=gb:AF267863.1 gb:NM_002868.1 AF267863 RAB5B, member RAS oncogene family RAB5B 5869 NM_001252036 /// NM_001252037 /// NM_002868 /// XM_005269051 /// XM_005269052 /// XM_006719540 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0030742 // GTP-dependent protein binding // inferred from direct assay 201277_s_at NM_004499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004499.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein AB (HNRPAB), mRNA. /FEA=mRNA /GEN=HNRPAB /PROD=heterogeneous nuclear ribonucleoprotein AB /DB_XREF=gi:4758541 /UG=Hs.81361 heterogeneous nuclear ribonucleoprotein AB /FL=gb:BC002625.1 gb:BC004561.1 gb:M65028.1 gb:NM_004499.1 NM_004499 heterogeneous nuclear ribonucleoprotein A/B HNRNPAB 3182 NM_004499 /// NM_031266 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201278_at N21202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21202 /FEA=EST /DB_XREF=gi:1126372 /DB_XREF=est:yx41e12.s1 /CLONE=IMAGE:264334 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 N21202 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921 DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay 201279_s_at BC003064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003064.1 /DEF=Homo sapiens, disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein), clone MGC:1764, mRNA, complete cds. /FEA=mRNA /PROD=disabled (Drosophila) homolog 2(mitogen-responsive phosphoprotein) /DB_XREF=gi:13111753 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 BC003064 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921 DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay 201280_s_at NM_001343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001343.1 /DEF=Homo sapiens disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) (DAB2), mRNA. /FEA=mRNA /GEN=DAB2 /PROD=disabled (Drosophila) homolog 2 /DB_XREF=gi:4503250 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 NM_001343 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921 DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay 201281_at NM_007002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007002.1 /DEF=Homo sapiens cell membrane glycoprotein, 110000M(r) (surface antigen) (GP110), mRNA. /FEA=mRNA /GEN=GP110 /PROD=cell membrane glycoprotein, 110000M(r) (surfaceantigen) /DB_XREF=gi:5901959 /UG=Hs.90107 cell membrane glycoprotein, 110000M(r) (surface antigen) /FL=gb:NM_007002.1 gb:D64154.1 NM_007002 adhesion regulating molecule 1 ADRM1 11047 NM_001281437 /// NM_001281438 /// NM_007002 /// NM_175573 /// XM_005260257 0006368 // transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0043248 // proteasome assembly // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0070628 // proteasome binding // inferred from direct assay 201282_at NM_002541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002541.1 /DEF=Homo sapiens oxoglutarate dehydrogenase (lipoamide) (OGDH), mRNA. /FEA=mRNA /GEN=OGDH /PROD=oxoglutarate dehydrogenase (lipoamide) /DB_XREF=gi:4505492 /UG=Hs.168669 oxoglutarate dehydrogenase (lipoamide) /FL=gb:BC004964.1 gb:NM_002541.1 gb:D10523.1 NM_002541 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) OGDH 4967 NM_001003941 /// NM_001165036 /// NM_002541 /// XM_005249759 /// XM_005249761 0006091 // generation of precursor metabolites and energy // inferred from sequence or structural similarity /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006104 // succinyl-CoA metabolic process // inferred from electronic annotation /// 0006554 // lysine catabolic process // traceable author statement /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061034 // olfactory bulb mitral cell layer development // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0045252 // oxoglutarate dehydrogenase complex // inferred from electronic annotation 0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0034602 // oxoglutarate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 201283_s_at J03068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03068.1 /DEF=Human DNF1552 (lung) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181629 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2 J03068 trafficking protein, kinesin binding 1 TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0050435 // beta-amyloid metabolic process // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from electronic annotation 201284_s_at NM_001640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001640.2 /DEF=Homo sapiens N-acylaminoacyl-peptide hydrolase (APEH), mRNA. /FEA=mRNA /GEN=APEH /PROD=N-acylaminoacyl-peptide hydrolase /DB_XREF=gi:9951916 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2 NM_001640 acylaminoacyl-peptide hydrolase APEH 327 NM_001640 /// XM_005265097 /// XM_005265098 0006508 // proteolysis // inferred from direct assay /// 0050435 // beta-amyloid metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201285_at NM_013446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013446.1 /DEF=Homo sapiens makorin, ring finger protein, 1 (MKRN1), mRNA. /FEA=mRNA /GEN=MKRN1 /PROD=makorin, ring finger protein, 1 /DB_XREF=gi:7305272 /UG=Hs.7838 makorin, ring finger protein, 1 /FL=gb:AL136812.1 gb:AF192784.1 gb:NM_013446.1 NM_013446 makorin ring finger protein 1 MKRN1 23608 NM_001145125 /// NM_001291663 /// NM_013446 /// NR_117084 0000209 // protein polyubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201286_at Z48199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z48199 /DEF=H.sapiens syndecan-1 gene (exons 2-5) /FEA=mRNA /DB_XREF=gi:666051 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1 Z48199 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 /// XM_005262620 /// XM_005262621 /// XM_005262622 /// XM_006712060 0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0055002 // striated muscle cell development // inferred from expression pattern /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201287_s_at NM_002997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002997.1 /DEF=Homo sapiens syndecan 1 (SDC1), mRNA. /FEA=mRNA /GEN=SDC1 /PROD=syndecan 1 /DB_XREF=gi:4506858 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1 NM_002997 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 /// XM_005262620 /// XM_005262621 /// XM_005262622 /// XM_006712060 0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0055002 // striated muscle cell development // inferred from expression pattern /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201288_at NM_001175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001175.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) beta (ARHGDIB), mRNA. /FEA=mRNA /GEN=ARHGDIB /PROD=Rho GDP dissociation inhibitor (GDI) beta /DB_XREF=gi:10835001 /UG=Hs.83656 Rho GDP dissociation inhibitor (GDI) beta /FL=gb:NM_001175.1 gb:L20688.1 NM_001175 Rho GDP dissociation inhibitor (GDI) beta ARHGDIB 397 NM_001175 0006928 // cellular component movement // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation 201289_at NM_001554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001554.1 /DEF=Homo sapiens cysteine-rich, angiogenic inducer, 61 (CYR61), mRNA. /FEA=mRNA /GEN=CYR61 /PROD=cysteine-rich, angiogenic inducer, 61 /DB_XREF=gi:4504612 /UG=Hs.8867 cysteine-rich, angiogenic inducer, 61 /FL=gb:BC001271.1 gb:U62015.1 gb:AF003594.1 gb:AF031385.1 gb:NM_001554.1 NM_001554 cysteine-rich, angiogenic inducer, 61 CYR61 3491 NM_001554 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002041 // intussusceptive angiogenesis // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from genetic interaction /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201290_at NM_014300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014300.1 /DEF=Homo sapiens signal peptidase complex (18kD) (SPC18), mRNA. /FEA=mRNA /GEN=SPC18 /PROD=signal peptidase complex (18kD) /DB_XREF=gi:7657608 /UG=Hs.9534 signal peptidase complex (18kD) /FL=gb:BC000359.1 gb:AF061737.1 gb:AF108945.1 gb:NM_014300.1 NM_014300 SEC11 homolog A (S. cerevisiae) SEC11A 23478 NM_001271918 /// NM_001271919 /// NM_001271920 /// NM_001271921 /// NM_001271922 /// NM_014300 /// NR_073518 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201291_s_at AU159942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159942 /FEA=EST /DB_XREF=gi:11021463 /DB_XREF=est:AU159942 /CLONE=Y79AA1000724 /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AU159942 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 /// XM_005257632 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000819 // sister chromatid segregation // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // /// 0006265 // DNA topological change // inferred from direct assay /// 0006266 // DNA ligation // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // not recorded /// 0006281 // DNA repair // non-traceable author statement /// 0006312 // mitotic recombination // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044774 // mitotic DNA integrity checkpoint // not recorded /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009295 // nucleoid // not recorded /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201292_at AL561834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL561834 /FEA=EST /DB_XREF=gi:12909658 /DB_XREF=est:AL561834 /CLONE=CS0DB005YC15 (3 prime) /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AL561834 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 /// XM_005257632 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000819 // sister chromatid segregation // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // /// 0006265 // DNA topological change // inferred from direct assay /// 0006266 // DNA ligation // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // not recorded /// 0006281 // DNA repair // non-traceable author statement /// 0006312 // mitotic recombination // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044774 // mitotic DNA integrity checkpoint // not recorded /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009295 // nucleoid // not recorded /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201293_x_at NM_021130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021130.1 /DEF=Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA. /FEA=mRNA /GEN=PPIA /PROD=peptidylprolyl isomerase A (cyclophilin A) /DB_XREF=gi:10863926 /UG=Hs.182937 peptidylprolyl isomerase A (cyclophilin A) /FL=gb:NM_021130.1 gb:BC000689.1 gb:BC005320.1 NM_021130 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 201294_s_at N24643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N24643 /FEA=EST /DB_XREF=gi:1138793 /DB_XREF=est:yx89f11.s1 /CLONE=IMAGE:268941 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 N24643 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201295_s_at BF111821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF111821 /FEA=EST /DB_XREF=gi:10941511 /DB_XREF=est:7l36a06.x1 /CLONE=IMAGE:3523474 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 BF111821 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201296_s_at NM_015626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015626.1 /DEF=Homo sapiens DKFZP564A122 protein (DKFZP564A122), mRNA. /FEA=mRNA /GEN=DKFZP564A122 /PROD=DKFZP564A122 protein /DB_XREF=gi:7661595 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 NM_015626 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201297_s_at AK023321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023321.1 /DEF=Homo sapiens cDNA FLJ13259 fis, clone OVARC1000876, moderately similar to MOB1 PROTEIN. /FEA=mRNA /DB_XREF=gi:10435206 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 AK023321 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201298_s_at BC003398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003398.1 /DEF=Homo sapiens, hypothetical protein FLJ10788, clone MGC:4929, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:13097287 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 BC003398 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201299_s_at NM_018221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018221.1 /DEF=Homo sapiens hypothetical protein FLJ10788 (FLJ10788), mRNA. /FEA=mRNA /GEN=FLJ10788 /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:8922670 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 NM_018221 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201300_s_at NM_000311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000311.1 /DEF=Homo sapiens prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP), mRNA. /FEA=mRNA /GEN=PRNP /PROD=prion protein /DB_XREF=gi:4506112 /UG=Hs.74621 prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) /FL=gb:AY008282.1 gb:M13899.1 gb:NM_000311.1 NM_000311 prion protein PRNP 5621 NM_000311 /// NM_001080121 /// NM_001080122 /// NM_001080123 /// NM_001271561 /// NM_183079 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006878 // cellular copper ion homeostasis // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032703 // negative regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070885 // negative regulation of calcineurin-NFAT signaling cascade // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 201301_s_at BC000182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000182.1 /DEF=Homo sapiens, annexin A4, clone MGC:2271, mRNA, complete cds. /FEA=mRNA /PROD=annexin A4 /DB_XREF=gi:12652858 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2 BC000182 annexin A4 ANXA4 307 NM_001153 /// XM_006712000 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201302_at NM_001153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001153.2 /DEF=Homo sapiens annexin A4 (ANXA4), mRNA. /FEA=mRNA /GEN=ANXA4 /PROD=annexin IV /DB_XREF=gi:4809272 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2 NM_001153 annexin A4 ANXA4 307 NM_001153 /// XM_006712000 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201303_at NM_014740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014740.1 /DEF=Homo sapiens KIAA0111 gene product (KIAA0111), mRNA. /FEA=mRNA /GEN=KIAA0111 /PROD=KIAA0111 gene product /DB_XREF=gi:7661919 /UG=Hs.79768 KIAA0111 gene product /FL=gb:BC003662.1 gb:BC004386.1 gb:D21853.1 gb:NM_014740.1 NM_014740 eukaryotic translation initiation factor 4A3 EIF4A3 9775 NM_014740 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201304_at NM_005000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005000.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) (NDUFA5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NDUFA5 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 5 /DB_XREF=gi:13699821 /UG=Hs.83916 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) /FL=gb:BC000813.1 gb:NM_005000.2 gb:U53468.1 gb:U64028.1 NM_005000 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 NDUFA5 4698 NM_001282419 /// NM_001282420 /// NM_001282421 /// NM_001282422 /// NM_001291304 /// NM_005000 /// NR_104168 /// NR_104169 /// NR_111925 /// NR_111926 /// XM_005250371 /// XR_426239 /// XR_428243 /// XR_432226 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation 201305_x_at AV712577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV712577 /FEA=EST /DB_XREF=gi:10731883 /DB_XREF=est:AV712577 /CLONE=DCAAUH03 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1 AV712577 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B ANP32B 10541 NM_006401 0006334 // nucleosome assembly // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042393 // histone binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 201306_s_at NM_006401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006401.1 /DEF=Homo sapiens acidic protein rich in leucines (SSP29), mRNA. /FEA=mRNA /GEN=SSP29 /PROD=acidic protein rich in leucines /DB_XREF=gi:5454087 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1 NM_006401 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B ANP32B 10541 NM_006401 0006334 // nucleosome assembly // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042393 // histone binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 201307_at AL534972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL534972 /FEA=EST /DB_XREF=gi:12798465 /DB_XREF=est:AL534972 /CLONE=CS0DF007YI02 (5 prime) /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1 AL534972 septin 11 SEPT11 55752 NM_018243 /// XM_005263120 /// XM_005263121 /// XM_005263122 /// XM_006714259 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201308_s_at NM_018243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018243.1 /DEF=Homo sapiens hypothetical protein FLJ10849 (FLJ10849), mRNA. /FEA=mRNA /GEN=FLJ10849 /PROD=hypothetical protein FLJ10849 /DB_XREF=gi:8922711 /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1 NM_018243 septin 11 SEPT11 55752 NM_018243 /// XM_005263120 /// XM_005263121 /// XM_005263122 /// XM_006714259 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201309_x_at U36189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36189.1 /DEF=Human p311 protein (hP311) mRNA, complete cds. /FEA=mRNA /GEN=hP311 /PROD=p311 protein /DB_XREF=gi:1244509 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1 U36189 neuronal regeneration related protein NREP 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 /// XM_006714732 /// XM_006714733 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201310_s_at NM_004772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004772.1 /DEF=Homo sapiens P311 protein (P311), mRNA. /FEA=mRNA /GEN=P311 /PROD=P311 protein /DB_XREF=gi:4758865 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1 NM_004772 neuronal regeneration related protein NREP 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 /// XM_006714732 /// XM_006714733 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201311_s_at AL515318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515318 /FEA=EST /DB_XREF=gi:12778811 /DB_XREF=est:AL515318 /CLONE=CL0BB030ZH05 (5 prime) /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1 AL515318 SH3 domain binding glutamate-rich protein like SH3BGRL 6451 NM_003022 0009967 // positive regulation of signal transduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201312_s_at NM_003022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003022.1 /DEF=Homo sapiens SH3 domain binding glutamic acid-rich protein like (SH3BGRL), mRNA. /FEA=mRNA /GEN=SH3BGRL /PROD=SH3 domain binding glutamic acid-rich proteinlike /DB_XREF=gi:4506924 /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1 NM_003022 SH3 domain binding glutamate-rich protein like SH3BGRL 6451 NM_003022 0009967 // positive regulation of signal transduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201313_at NM_001975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001975.1 /DEF=Homo sapiens enolase 2, (gamma, neuronal) (ENO2), mRNA. /FEA=mRNA /GEN=ENO2 /PROD=enolase 2, (gamma, neuronal) /DB_XREF=gi:5803010 /UG=Hs.146580 enolase 2, (gamma, neuronal) /FL=gb:BC002745.1 gb:NM_001975.1 gb:M22349.1 NM_001975 enolase 2 (gamma, neuronal) ENO2 2026 NM_001975 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201314_at NM_006374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006374.1 /DEF=Homo sapiens serinethreonine kinase 25 (Ste20, yeast homolog) (STK25), mRNA. /FEA=mRNA /GEN=STK25 /PROD=serinethreonine kinase 25 (Ste20, yeasthomolog) /DB_XREF=gi:5454173 /UG=Hs.155206 serinethreonine kinase 25 (Ste20, yeast homolog) /FL=gb:D63780.1 gb:NM_006374.1 NM_006374 serine/threonine kinase 25 STK25 10494 NM_001271977 /// NM_001271978 /// NM_001271979 /// NM_001271980 /// NM_001282305 /// NM_001282306 /// NM_001282307 /// NM_001282308 /// NM_006374 /// XM_006712197 /// XM_006712198 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006979 // response to oxidative stress // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0045595 // regulation of cell differentiation // not recorded /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from direct assay 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201315_x_at NM_006435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006435.1 /DEF=Homo sapiens interferon induced transmembrane protein 2 (1-8D) (IFITM2), mRNA. /FEA=mRNA /GEN=IFITM2 /PROD=interferon induced transmembrane protein 2(1-8D) /DB_XREF=gi:10835237 /UG=Hs.174195 interferon induced transmembrane protein 2 (1-8D) /FL=gb:NM_006435.1 NM_006435 interferon induced transmembrane protein 2 IFITM2 10581 NM_006435 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201316_at AL523904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523904 /FEA=EST /DB_XREF=gi:12787397 /DB_XREF=est:AL523904 /CLONE=CS0DC003YB07 (3 prime) /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1 AL523904 proteasome (prosome, macropain) subunit, alpha type, 2 PSMA2 5683 NM_002787 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201317_s_at NM_002787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002787.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2), mRNA. /FEA=mRNA /GEN=PSMA2 /PROD=proteasome (prosome, macropain) subunit, alphatype, 2 /DB_XREF=gi:4506180 /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1 NM_002787 proteasome (prosome, macropain) subunit, alpha type, 2 PSMA2 5683 NM_002787 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201318_s_at NM_006471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1 NM_006471 myosin, light chain 12A, regulatory, non-sarcomeric /// myosin, light chain 12B, regulatory MYL12A /// MYL12B 10627 /// 103910 NM_001144944 /// NM_001144945 /// NM_001144946 /// NM_006471 /// NM_033546 /// XM_005258076 /// XM_005258077 /// XM_005258078 0006936 // muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201319_at NM_006471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1 NM_006471 myosin, light chain 12A, regulatory, non-sarcomeric MYL12A 10627 NM_006471 /// XM_005258076 /// XM_005258077 /// XM_005258078 0008360 // regulation of cell shape // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201320_at BF663402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF663402 /FEA=EST /DB_XREF=gi:11937297 /DB_XREF=est:602144558F1 /CLONE=IMAGE:4297695 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1 BF663402 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 /// XM_005269101 /// XM_005269102 /// XM_005269103 /// XM_005269104 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201321_s_at NM_003075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003075.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (SMARCC2), mRNA. /FEA=mRNA /GEN=SMARCC2 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 2 /DB_XREF=gi:4507080 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1 NM_003075 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 /// XM_005269101 /// XM_005269102 /// XM_005269103 /// XM_005269104 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201322_at NM_001686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001686.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ATP5B /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, beta polypeptide /DB_XREF=gi:4502294 /UG=Hs.25 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide /FL=gb:D00022.1 gb:NM_001686.1 NM_001686 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide ATP5B 506 NM_001686 0001525 // angiogenesis // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006091 // generation of precursor metabolites and energy // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005754 // mitochondrial proton-transporting ATP synthase, catalytic core // non-traceable author statement /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred by curator /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from mutant phenotype 201323_at NM_006824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006824.1 /DEF=Homo sapiens nucleolar protein p40; homolog of yeast EBNA1-binding protein (P40), mRNA. /FEA=mRNA /GEN=P40 /PROD=nucleolar protein p40; homolog of yeastEBNA1-binding protein /DB_XREF=gi:5803110 /UG=Hs.74407 nucleolar protein p40; homolog of yeast EBNA1-binding protein /FL=gb:U86602.1 gb:NM_006824.1 NM_006824 EBNA1 binding protein 2 /// microRNA 6733 EBNA1BP2 /// MIR6733 10969 /// 102465439 NM_001159936 /// NM_006824 /// NR_106791 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 201324_at NM_001423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1 NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 201325_s_at NM_001423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1 NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 201326_at BE737030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE737030 /FEA=EST /DB_XREF=gi:10151022 /DB_XREF=est:601304610F1 /CLONE=IMAGE:3639098 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1 BE737030 chaperonin containing TCP1, subunit 6A (zeta 1) CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201327_s_at NM_001762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001762.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 6A (zeta 1) (CCT6A), mRNA. /FEA=mRNA /GEN=CCT6A /PROD=chaperonin containing TCP1, subunit 6A (zeta 1) /DB_XREF=gi:4502642 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1 NM_001762 chaperonin containing TCP1, subunit 6A (zeta 1) CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201328_at AL575509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL575509 /FEA=EST /DB_XREF=gi:12936742 /DB_XREF=est:AL575509 /CLONE=CS0DI059YP21 (3 prime) /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1 AL575509 v-ets avian erythroblastosis virus E26 oncogene homolog 2 ETS2 2114 NM_001256295 /// NM_005239 /// XM_005260935 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201329_s_at NM_005239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005239.1 /DEF=Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 2 (ETS2), mRNA. /FEA=mRNA /GEN=ETS2 /PROD=v-ets avian erythroblastosis virus E26 oncogenehomolog 2 /DB_XREF=gi:4885220 /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1 NM_005239 v-ets avian erythroblastosis virus E26 oncogene homolog 2 ETS2 2114 NM_001256295 /// NM_005239 /// XM_005260935 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201330_at NM_002887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002887.1 /DEF=Homo sapiens arginyl-tRNA synthetase (RARS), mRNA. /FEA=mRNA /GEN=RARS /PROD=arginyl-tRNA synthetase /DB_XREF=gi:4506428 /UG=Hs.180832 arginyl-tRNA synthetase /FL=gb:BC000528.1 gb:NM_002887.1 NM_002887 arginyl-tRNA synthetase RARS 5917 NM_002887 /// XM_005265957 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034618 // arginine binding // inferred from electronic annotation 201331_s_at BC004973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004973.1 /DEF=Homo sapiens, signal transducer and activator of transcription 6, interleukin-4 induced, clone MGC:3649, mRNA, complete cds. /FEA=mRNA /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:13436385 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1 BC004973 signal transducer and activator of transcription 6, interleukin-4 induced STAT6 6778 NM_001178078 /// NM_001178079 /// NM_001178080 /// NM_001178081 /// NM_003153 /// NR_033659 /// XM_006719573 /// XM_006719574 /// XM_006719575 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 1902170 // cellular response to reactive nitrogen species // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201332_s_at NM_003153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003153.1 /DEF=Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA. /FEA=mRNA /GEN=STAT6 /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:4507258 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1 NM_003153 signal transducer and activator of transcription 6, interleukin-4 induced STAT6 6778 NM_001178078 /// NM_001178079 /// NM_001178080 /// NM_001178081 /// NM_003153 /// NR_033659 /// XM_006719573 /// XM_006719574 /// XM_006719575 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 1902170 // cellular response to reactive nitrogen species // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201333_s_at AI807672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI807672 /FEA=EST /DB_XREF=gi:5394238 /DB_XREF=est:wf49f10.x1 /CLONE=IMAGE:2358955 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 AI807672 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201334_s_at AB002380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002380.1 /DEF=Human mRNA for KIAA0382 gene, partial cds. /FEA=mRNA /GEN=KIAA0382 /DB_XREF=gi:2224704 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 AB002380 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201335_s_at NM_015313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015313.1 /DEF=Homo sapiens KIAA0382 protein; leukemia-associated rho guanine nucleotide exchange factor (GEF) (ARHGEF12), mRNA. /FEA=mRNA /GEN=ARHGEF12 /PROD=KIAA0382 protein; leukemia-associated rhoguanine nucleotide exchange factor (GEF) /DB_XREF=gi:7662087 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 NM_015313 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201336_at BC003570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003570.1 /DEF=Homo sapiens, Similar to vesicle-associated membrane protein 3, clone MGC:2110, mRNA, complete cds. /FEA=mRNA /PROD=Similar to vesicle-associated membrane protein3 /DB_XREF=gi:13097737 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2 BC003570 vesicle-associated membrane protein 3 VAMP3 9341 NM_004781 0001921 // positive regulation of receptor recycling // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 201337_s_at NM_004781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004781.2 /DEF=Homo sapiens vesicle-associated membrane protein 3 (cellubrevin) (VAMP3), mRNA. /FEA=mRNA /GEN=VAMP3 /PROD=vesicle-associated membrane protein 3 /DB_XREF=gi:9257252 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2 NM_004781 vesicle-associated membrane protein 3 VAMP3 9341 NM_004781 0001921 // positive regulation of receptor recycling // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 201338_x_at NM_002097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002097.1 /DEF=Homo sapiens general transcription factor IIIA (GTF3A), mRNA. /FEA=mRNA /GEN=GTF3A /PROD=general transcription factor IIIA /DB_XREF=gi:4753158 /UG=Hs.75113 general transcription factor IIIA /FL=gb:D32257.1 gb:NM_002097.1 NM_002097 general transcription factor IIIA GTF3A 2971 NM_002097 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201339_s_at NM_002979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002979.1 /DEF=Homo sapiens sterol carrier protein 2 (SCP2), mRNA. /FEA=mRNA /GEN=SCP2 /PROD=sterol carrier protein 2 /DB_XREF=gi:4506822 /UG=Hs.75760 sterol carrier protein 2 /FL=gb:M75883.1 gb:M75884.1 gb:M55421.1 gb:NM_002979.1 NM_002979 sterol carrier protein 2 SCP2 6342 NM_001007098 /// NM_001007099 /// NM_001007100 /// NM_001007250 /// NM_001193599 /// NM_001193600 /// NM_001193617 /// NM_002979 /// XM_005271103 /// XM_005271104 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015914 // phospholipid transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // non-traceable author statement /// 0032959 // inositol trisphosphate biosynthetic process // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045940 // positive regulation of steroid metabolic process // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 1901373 // lipid hydroperoxide transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation /// 0033814 // propanoyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0070538 // oleic acid binding // inferred from direct assay 201340_s_at AF010314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010314.1 /DEF=Homo sapiens Pig10 (PIG10) mRNA, complete cds. /FEA=mRNA /GEN=PIG10 /PROD=Pig10 /DB_XREF=gi:2415303 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1 AF010314 ectodermal-neural cortex 1 (with BTB domain) ENC1 8507 NM_001256574 /// NM_001256575 /// NM_001256576 /// NM_003633 /// NR_046318 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201341_at NM_003633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003633.1 /DEF=Homo sapiens ectodermal-neural cortex (with BTB-like domain) (ENC1), mRNA. /FEA=mRNA /GEN=ENC1 /PROD=ectodermal-neural cortex (with BTB-like domain) /DB_XREF=gi:4505460 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1 NM_003633 ectodermal-neural cortex 1 (with BTB domain) ENC1 8507 NM_001256574 /// NM_001256575 /// NM_001256576 /// NM_003633 /// NR_046318 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201342_at NM_003093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003093.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide C (SNRPC), mRNA. /FEA=mRNA /GEN=SNRPC /PROD=small nuclear ribonucleoprotein polypeptide C /DB_XREF=gi:4507126 /UG=Hs.1063 small nuclear ribonucleoprotein polypeptide C /FL=gb:NM_003093.1 NM_003093 small nuclear ribonucleoprotein polypeptide C SNRPC 6631 NM_003093 /// NR_029472 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000395 // mRNA 5'-splice site recognition // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay 0000243 // commitment complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071004 // U2-type prespliceosome // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0030619 // U1 snRNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201343_at BE621259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE621259 /FEA=EST /DB_XREF=gi:9892197 /DB_XREF=est:601493415F1 /CLONE=IMAGE:3895850 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BE621259 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201344_at BF196642 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196642 /FEA=EST /DB_XREF=gi:11084786 /DB_XREF=est:7m93c12.x1 /CLONE=IMAGE:3562750 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BF196642 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201345_s_at NM_003339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003339.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) (UBE2D2), mRNA. /FEA=mRNA /GEN=UBE2D2 /PROD=ubiquitin-conjugating enzyme E2D 2 (homologousto yeast UBC45) /DB_XREF=gi:4507774 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 NM_003339 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201346_at NM_024551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024551.1 /DEF=Homo sapiens hypothetical protein FLJ21432 (FLJ21432), mRNA. /FEA=mRNA /GEN=FLJ21432 /PROD=hypothetical protein FLJ21432 /DB_XREF=gi:13375714 /UG=Hs.11641 hypothetical protein FLJ21432 /FL=gb:NM_024551.1 gb:BC004906.1 NM_024551 adiponectin receptor 2 ADIPOR2 79602 NM_024551 /// XM_005253789 /// XM_006719018 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0033211 // adiponectin-activated signaling pathway // not recorded /// 0046326 // positive regulation of glucose import // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042562 // hormone binding // not recorded /// 0042562 // hormone binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201347_x_at NM_012203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012203.1 /DEF=Homo sapiens glyoxylate reductasehydroxypyruvate reductase (GRHPR), mRNA. /FEA=mRNA /GEN=GRHPR /PROD=glyoxylate reductasehydroxypyruvate reductase /DB_XREF=gi:6912395 /UG=Hs.155742 glyoxylate reductasehydroxypyruvate reductase /FL=gb:AF113215.1 gb:BC000605.1 gb:BC003131.1 gb:AF146018.1 gb:AF113251.1 gb:AF134895.1 gb:NM_012203.1 NM_012203 glyoxylate reductase/hydroxypyruvate reductase GRHPR 9380 NM_012203 /// XM_005251631 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007588 // excretion // inferred from mutant phenotype /// 0008152 // metabolic process // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043648 // dicarboxylic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0008465 // glycerate dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016618 // hydroxypyruvate reductase activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay 201348_at NM_002084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002084.2 /DEF=Homo sapiens glutathione peroxidase 3 (plasma) (GPX3), mRNA. /FEA=mRNA /GEN=GPX3 /PROD=plasma glutathione peroxidase 3 precursor /DB_XREF=gi:6006000 /UG=Hs.172153 glutathione peroxidase 3 (plasma) /FL=gb:D00632.1 gb:NM_002084.2 gb:AF217787.1 NM_002084 glutathione peroxidase 3 (plasma) GPX3 2878 NM_002084 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // traceable author statement /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // not recorded /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0008134 // transcription factor binding // traceable author statement /// 0008430 // selenium binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201349_at NM_004252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004252.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 (SLC9A3R1), mRNA. /FEA=mRNA /GEN=SLC9A3R1 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 3 regulatory factor 1 /DB_XREF=gi:4759139 /UG=Hs.184276 solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 /FL=gb:BC001443.1 gb:BC003361.1 gb:AF036241.1 gb:AF015926.1 gb:NM_004252.1 NM_004252 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 SLC9A3R1 9368 NM_004252 0003096 // renal sodium ion transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030033 // microvillus assembly // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from electronic annotation /// 0032415 // regulation of sodium:proton antiporter activity // non-traceable author statement /// 0032416 // negative regulation of sodium:proton antiporter activity // inferred from electronic annotation /// 0032782 // bile acid secretion // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034635 // glutathione transport // inferred from sequence or structural similarity /// 0044062 // regulation of excretion // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0070293 // renal absorption // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0097291 // renal phosphate ion absorption // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay /// 0097225 // sperm midpiece // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017081 // chloride channel regulator activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0050780 // dopamine receptor binding // inferred from electronic annotation /// 0070851 // growth factor receptor binding // inferred from physical interaction 201350_at NM_004475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004475.1 /DEF=Homo sapiens flotillin 2 (FLOT2), mRNA. /FEA=mRNA /GEN=FLOT2 /PROD=flotillin 2 /DB_XREF=gi:4758393 /UG=Hs.184488 flotillin 2 /FL=gb:NM_004475.1 gb:M60922.1 NM_004475 flotillin 2 FLOT2 2319 NM_004475 /// XM_005257950 /// XM_005257952 /// XM_005257953 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 1902992 // negative regulation of amyloid precursor protein catabolic process // inferred from mutant phenotype 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 201351_s_at AF070656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070656.1 /DEF=Homo sapiens FtsH homolog mRNA, complete cds. /FEA=mRNA /PROD=FtsH homolog /DB_XREF=gi:4454687 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1 AF070656 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201352_at NM_014263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014263.1 /DEF=Homo sapiens YME1 (S.cerevisiae)-like 1 (YME1L1), mRNA. /FEA=mRNA /GEN=YME1L1 /PROD=YME1 (S.cerevisiae)-like 1 /DB_XREF=gi:7657688 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1 NM_014263 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201353_s_at AI653126 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653126 /FEA=EST /DB_XREF=gi:4737105 /DB_XREF=est:wb43c08.x1 /CLONE=IMAGE:2308430 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 AI653126 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201354_s_at AA788652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA788652 /FEA=EST /DB_XREF=gi:2848772 /DB_XREF=est:ah30a09.s1 /CLONE=1240312 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 AA788652 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201355_s_at NM_013449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013449.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 2A (BAZ2A), mRNA. /FEA=mRNA /GEN=BAZ2A /PROD=bromodomain adjacent to zinc finger domain, 2A /DB_XREF=gi:7304920 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 NM_013449 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201356_at BF129339 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF129339 /FEA=EST /DB_XREF=gi:10968379 /DB_XREF=est:601810961R1 /CLONE=IMAGE:4053975 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1 BF129339 splicing factor 3a, subunit 1, 120kDa SF3A1 10291 NM_001005409 /// NM_005877 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005684 // U2-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201357_s_at NM_005877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005877.1 /DEF=Homo sapiens splicing factor 3a, subunit 1, 120kD (SF3A1), mRNA. /FEA=mRNA /GEN=SF3A1 /PROD=splicing factor 3a, subunit 1, 120kD /DB_XREF=gi:5032086 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1 NM_005877 splicing factor 3a, subunit 1, 120kDa SF3A1 10291 NM_001005409 /// NM_005877 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005684 // U2-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201358_s_at NM_016451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1 NM_016451 coatomer protein complex, subunit beta 1 COPB1 1315 NM_001144061 /// NM_001144062 /// NM_016451 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201359_at NM_016451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1 NM_016451 coatomer protein complex, subunit beta 1 COPB1 1315 NM_001144061 /// NM_001144062 /// NM_016451 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201360_at NM_000099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000099.1 /DEF=Homo sapiens cystatin C (amyloid angiopathy and cerebral hemorrhage) (CST3), mRNA. /FEA=mRNA /GEN=CST3 /PROD=cystatin C (amyloid angiopathy and cerebralhemorrhage) /DB_XREF=gi:4503106 /UG=Hs.135084 cystatin C (amyloid angiopathy and cerebral hemorrhage) /FL=gb:NM_000099.1 NM_000099 cystatin C CST3 1471 NM_000099 /// NM_001288614 0006952 // defense response // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010703 // negative regulation of histolysis // inferred by curator /// 0010711 // negative regulation of collagen catabolic process // inferred from expression pattern /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from expression pattern /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0034103 // regulation of tissue remodeling // inferred from expression pattern /// 0043206 // extracellular fibril organization // inferred from genetic interaction /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0060311 // negative regulation of elastin catabolic process // inferred from mutant phenotype /// 0060313 // negative regulation of blood vessel remodeling // inferred from expression pattern 0005576 // extracellular region // inferred from mutant phenotype /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 201361_at NM_024092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024092.1 /DEF=Homo sapiens hypothetical protein MGC5508 (MGC5508), mRNA. /FEA=mRNA /GEN=MGC5508 /PROD=hypothetical protein MGC5508 /DB_XREF=gi:13129091 /UG=Hs.13662 hypothetical protein MGC5508 /FL=gb:BC001309.1 gb:NM_024092.1 NM_024092 transmembrane protein 109 TMEM109 79073 NM_024092 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0071480 // cellular response to gamma radiation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201362_at AF205218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF205218.1 /DEF=Homo sapiens NS1-binding protein-like protein mRNA, complete cds. /FEA=mRNA /PROD=NS1-binding protein-like protein /DB_XREF=gi:12003206 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1 AF205218 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 /// NM_016389 /// XM_005244843 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201363_s_at AB020657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020657.1 /DEF=Homo sapiens mRNA for KIAA0850 protein, complete cds. /FEA=mRNA /GEN=KIAA0850 /PROD=KIAA0850 protein /DB_XREF=gi:4240188 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1 AB020657 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 /// NM_016389 /// XM_005244843 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201364_s_at AF242521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF242521.1 /DEF=Homo sapiens ornithine decarboxylase antizyme mRNA, complete cds. /FEA=mRNA /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:9802039 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1 AF242521 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201365_at NM_002537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002537.1 /DEF=Homo sapiens ornithine decarboxylase antizyme 2 (OAZ2), mRNA. /FEA=mRNA /GEN=OAZ2 /PROD=ornithine decarboxylase antizyme 2 /DB_XREF=gi:9845506 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1 NM_002537 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201366_at NM_004034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004034.1 /DEF=Homo sapiens annexin A7 (ANXA7), transcript variant 2, mRNA. /FEA=mRNA /GEN=ANXA7 /PROD=annexin VII isoform 2 /DB_XREF=gi:4809278 /UG=Hs.78637 annexin A7 /FL=gb:NM_004034.1 NM_004034 annexin A7 ANXA7 310 NM_001156 /// NM_004034 /// XM_005269738 /// XM_005269739 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007599 // hemostasis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009992 // cellular water homeostasis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0035176 // social behavior // inferred from expression pattern /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201367_s_at AI356398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI356398 /FEA=EST /DB_XREF=gi:4108019 /DB_XREF=est:qz26f08.x1 /CLONE=IMAGE:2028039 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 AI356398 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201368_at U07802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U07802 /DEF=Human Tis11d gene, complete cds /FEA=mRNA /DB_XREF=gi:984508 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 U07802 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201369_s_at NM_006887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006887.1 /DEF=Homo sapiens butyrate response factor 2 (EGF-response factor 2) (BRF2), mRNA. /FEA=mRNA /GEN=BRF2 /PROD=butyrate response factor 2 (EGF-response factor2) /DB_XREF=gi:5901899 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 NM_006887 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201370_s_at AU145232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145232 /FEA=EST /DB_XREF=gi:11006753 /DB_XREF=est:AU145232 /CLONE=HEMBA1004254 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 AU145232 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201371_s_at AF062537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062537.1 /DEF=Homo sapiens cullin 3 mRNA, complete cds. /FEA=mRNA /PROD=cullin 3 /DB_XREF=gi:3139078 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 AF062537 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201372_s_at NM_003590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003590.1 /DEF=Homo sapiens cullin 3 (CUL3), mRNA. /FEA=mRNA /GEN=CUL3 /PROD=cullin 3 /DB_XREF=gi:4503164 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 NM_003590 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201373_at NM_000445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000445.1 /DEF=Homo sapiens plectin 1, intermediate filament binding protein, 500kD (PLEC1), mRNA. /FEA=mRNA /GEN=PLEC1 /PROD=plectin 1, intermediate filament bindingprotein, 500kD /DB_XREF=gi:4505876 /UG=Hs.79706 plectin 1, intermediate filament binding protein, 500kD /FL=gb:U53204.1 gb:NM_000445.1 NM_000445 plectin PLEC 5339 NM_000445 /// NM_201378 /// NM_201379 /// NM_201380 /// NM_201381 /// NM_201382 /// NM_201383 /// NM_201384 /// XM_005250976 /// XM_005250977 /// XM_005250978 /// XM_005250979 /// XM_005250980 /// XM_005250981 /// XM_005250982 /// XM_005250983 /// XM_005250984 /// XM_006716588 /// XM_006716589 /// XM_006716590 /// XM_006716591 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046417 // chorismate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201374_x_at AI379894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI379894 /FEA=EST /DB_XREF=gi:4189747 /DB_XREF=est:tc64g11.x1 /CLONE=IMAGE:2069444 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1 AI379894 protein phosphatase 2, catalytic subunit, beta isozyme PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein dephosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201375_s_at NM_004156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004156.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (PPP2CB), mRNA. /FEA=mRNA /GEN=PPP2CB /PROD=protein phosphatase 2 (formerly 2A), catalyticsubunit, beta isoform /DB_XREF=gi:4758951 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1 NM_004156 protein phosphatase 2, catalytic subunit, beta isozyme PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein dephosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201376_s_at AI591354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI591354 /FEA=EST /DB_XREF=gi:4600402 /DB_XREF=est:ts10e04.x1 /CLONE=IMAGE:2228190 /UG=Hs.808 heterogeneous nuclear ribonucleoprotein F /FL=gb:BC001432.1 gb:L28010.1 gb:NM_004966.1 AI591354 heterogeneous nuclear ribonucleoprotein F HNRNPF 3185 NM_001098204 /// NM_001098205 /// NM_001098206 /// NM_001098207 /// NM_001098208 /// NM_004966 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201377_at NM_014847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1 NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201378_s_at NM_014847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1 NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201379_s_at NM_003288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003288.1 /DEF=Homo sapiens tumor protein D52-like 2 (TPD52L2), mRNA. /FEA=mRNA /GEN=TPD52L2 /PROD=tumor protein D52-like 2 /DB_XREF=gi:4507642 /UG=Hs.154718 tumor protein D52-like 2 /FL=gb:AF004430.1 gb:NM_003288.1 NM_003288 tumor protein D52-like 2 TPD52L2 7165 NM_001243891 /// NM_001243892 /// NM_001243894 /// NM_001243895 /// NM_003288 /// NM_199359 /// NM_199360 /// NM_199361 /// NM_199362 /// NM_199363 /// NR_045090 0042127 // regulation of cell proliferation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201380_at NM_006371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006371.1 /DEF=Homo sapiens cartilage associated protein (CRTAP), mRNA. /FEA=mRNA /GEN=CRTAP /PROD=cartilage associated protein /DB_XREF=gi:5453600 /UG=Hs.155481 cartilage associated protein /FL=gb:NM_006371.1 NM_006371 cartilage associated protein CRTAP 10491 NM_006371 0007283 // spermatogenesis // inferred from electronic annotation /// 0018400 // peptidyl-proline hydroxylation to 3-hydroxy-L-proline // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity /// 1901874 // negative regulation of post-translational protein modification // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0032991 // macromolecular complex // inferred from sequence or structural similarity 0032403 // protein complex binding // inferred from sequence or structural similarity 201381_x_at AF057356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF057356.1 /DEF=Homo sapiens calcyclin binding protein mRNA, complete cds. /FEA=mRNA /PROD=calcyclin binding protein /DB_XREF=gi:3063652 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1 AF057356 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201382_at NM_014412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014412.1 /DEF=Homo sapiens calcyclin binding protein (CACYBP), mRNA. /FEA=mRNA /GEN=CACYBP /PROD=calcyclin binding protein /DB_XREF=gi:7656951 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1 NM_014412 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201383_s_at AL044170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044170 /FEA=EST /DB_XREF=gi:5935951 /DB_XREF=est:DKFZp434P2128_s1 /CLONE=DKFZp434P2128 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1 AL044170 neighbor of BRCA1 gene 1 NBR1 4077 NM_001291571 /// NM_001291572 /// NM_005899 /// NM_031858 /// NM_031862 /// XM_006721903 0016236 // macroautophagy // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from direct assay 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from sequence or structural similarity 201384_s_at NM_005899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005899.1 /DEF=Homo sapiens membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) (M17S2), mRNA. /FEA=mRNA /GEN=M17S2 /PROD=membrane component, chromosome 17, surfacemarker 2 (ovarian carcinoma antigen CA125) /DB_XREF=gi:5174504 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1 NM_005899 neighbor of BRCA1 gene 1 NBR1 4077 NM_001291571 /// NM_001291572 /// NM_005899 /// NM_031858 /// NM_031862 /// XM_006721903 0016236 // macroautophagy // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from direct assay 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from sequence or structural similarity 201385_at NM_001358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001358.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 (DDX15), mRNA. /FEA=mRNA /GEN=DDX15 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /DB_XREF=gi:4557516 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1 NM_001358 DEAH (Asp-Glu-Ala-His) box helicase 15 DHX15 1665 NM_001358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201386_s_at AF279891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279891.1 /DEF=Homo sapiens dead box protein 15 mRNA, complete cds. /FEA=mRNA /PROD=dead box protein 15 /DB_XREF=gi:9624452 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1 AF279891 DEAH (Asp-Glu-Ala-His) box helicase 15 DHX15 1665 NM_001358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201387_s_at NM_004181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004181.1 /DEF=Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA. /FEA=mRNA /GEN=UCHL1 /PROD=ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase) /DB_XREF=gi:4759283 /UG=Hs.76118 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) /FL=gb:BC000332.1 gb:BC005117.1 gb:NM_004181.1 NM_004181 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) UCHL1 7345 NM_004181 0002931 // response to ischemia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042755 // eating behavior // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201388_at NM_002809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002809.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 (PSMD3), mRNA. /FEA=mRNA /GEN=PSMD3 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 3 /DB_XREF=gi:4506228 /UG=Hs.9736 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 /FL=gb:BC000074.1 gb:BC004859.1 gb:D67025.1 gb:AF091075.1 gb:NM_002809.1 NM_002809 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 PSMD3 5709 NM_002809 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201389_at NM_002205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002205.1 /DEF=Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), mRNA. /FEA=mRNA /GEN=ITGA5 /PROD=integrin alpha 5 precursor /DB_XREF=gi:4504750 /UG=Hs.149609 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) /FL=gb:NM_002205.1 NM_002205 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) ITGA5 3678 NM_002205 0001525 // angiogenesis // traceable author statement /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0033631 // cell-cell adhesion mediated by integrin // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001726 // ruffle // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 201390_s_at NM_001320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001320.1 /DEF=Homo sapiens casein kinase 2, beta polypeptide (CSNK2B), mRNA. /FEA=mRNA /GEN=CSNK2B /PROD=casein kinase 2, beta polypeptide /DB_XREF=gi:10334850 /UG=Hs.165843 casein kinase 2, beta polypeptide /FL=gb:NM_001320.1 NM_001320 casein kinase 2, beta polypeptide CSNK2B 1460 NM_001282385 /// NM_001320 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from mutant phenotype /// 0033211 // adiponectin-activated signaling pathway // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043623 // cellular protein complex assembly // non-traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // non-traceable author statement /// 0051101 // regulation of DNA binding // non-traceable author statement /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005956 // protein kinase CK2 complex // non-traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019887 // protein kinase regulator activity // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201391_at NM_016292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016292.1 /DEF=Homo sapiens heat shock protein 75 (TRAP1), mRNA. /FEA=mRNA /GEN=TRAP1 /PROD=tumor necrosis factor type 1 receptor associatedprotein /DB_XREF=gi:7706484 /UG=Hs.182366 heat shock protein 75 /FL=gb:BC002994.1 gb:AF154108.1 gb:NM_016292.1 NM_016292 TNF receptor-associated protein 1 TRAP1 10131 NM_001272049 /// NM_016292 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 1901856 // negative regulation of cellular respiration // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201392_s_at BG031974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG031974 /FEA=EST /DB_XREF=gi:12422804 /DB_XREF=est:602300668F1 /CLONE=IMAGE:4402217 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1 BG031974 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031995 // insulin-like growth factor II binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201393_s_at NM_000876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000876.1 /DEF=Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA. /FEA=mRNA /GEN=IGF2R /PROD=insulin-like growth factor 2 receptor /DB_XREF=gi:4504610 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1 NM_000876 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031995 // insulin-like growth factor II binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201394_s_at U23946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U23946.1 /DEF=Human putative tumor suppressor (LUCA15) mRNA, complete cds. /FEA=mRNA /GEN=LUCA15 /DB_XREF=gi:1244403 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1 U23946 RNA binding motif protein 5 RBM5 10181 NM_005778 /// NR_036627 /// XM_006712917 /// XM_006712918 /// XM_006712919 /// XM_006712920 /// XR_427245 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201395_at NM_005778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005778.1 /DEF=Homo sapiens RNA binding motif protein 5 (RBM5), mRNA. /FEA=mRNA /GEN=RBM5 /PROD=RNA binding motif protein 5 /DB_XREF=gi:5032030 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1 NM_005778 RNA binding motif protein 5 RBM5 10181 NM_005778 /// NR_036627 /// XM_006712917 /// XM_006712918 /// XM_006712919 /// XM_006712920 /// XR_427245 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201396_s_at NM_003021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003021.2 /DEF=Homo sapiens small glutamine-rich tetratricopeptide repeat (TPR)-containing (SGT), mRNA. /FEA=mRNA /GEN=SGT /PROD=small glutamine-rich tetratricopeptide /DB_XREF=gi:13259553 /UG=Hs.203910 small glutamine-rich tetratricopeptide repeat (TPR)-containing /FL=gb:BC000390.1 gb:NM_003021.2 gb:BC005165.1 gb:AL050156.1 NM_003021 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha SGTA 6449 NM_003021 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201397_at NM_006623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006623.1 /DEF=Homo sapiens phosphoglycerate dehydrogenase (PHGDH), mRNA. /FEA=mRNA /GEN=PHGDH /PROD=phosphoglycerate dehydrogenase /DB_XREF=gi:5729973 /UG=Hs.3343 phosphoglycerate dehydrogenase /FL=gb:BC000303.1 gb:BC001349.1 gb:AF006043.1 gb:NM_006623.1 gb:AF171237.1 NM_006623 phosphoglycerate dehydrogenase PHGDH 26227 NM_006623 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0006566 // threonine metabolic process // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021782 // glial cell development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022402 // cell cycle process // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004617 // phosphoglycerate dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201398_s_at BC000687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000687.1 /DEF=Homo sapiens, translocating chain-associating membrane protein, clone MGC:784, mRNA, complete cds. /FEA=mRNA /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:12653796 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1 BC000687 translocation associated membrane protein 1 TRAM1 23471 NM_014294 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201399_s_at NM_014294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014294.1 /DEF=Homo sapiens translocating chain-associating membrane protein (TRAM), mRNA. /FEA=mRNA /GEN=TRAM /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:7657654 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1 NM_014294 translocation associated membrane protein 1 TRAM1 23471 NM_014294 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201400_at NM_002795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002795.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 3 (PSMB3), mRNA. /FEA=mRNA /GEN=PSMB3 /PROD=proteasome (prosome, macropain) subunit, betatype, 3 /DB_XREF=gi:4506196 /UG=Hs.82793 proteasome (prosome, macropain) subunit, beta type, 3 /FL=gb:NM_002795.1 gb:D26598.1 NM_002795 proteasome (prosome, macropain) subunit, beta type, 3 PSMB3 5691 NM_002795 /// NR_104194 /// NR_104195 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201401_s_at M80776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80776.1 /DEF=Human beta-adrenergic receptor kinase 1 mRNA, complete cds. /FEA=mRNA /GEN=receptor kinase /PROD=receptor kinase /DB_XREF=gi:179334 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2 M80776 adrenergic, beta, receptor kinase 1 ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from sequence or structural similarity /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 201402_at NM_001619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001619.2 /DEF=Homo sapiens adrenergic, beta, receptor kinase 1 (ADRBK1), mRNA. /FEA=mRNA /GEN=ADRBK1 /PROD=beta adrenergic receptor kinase 1 /DB_XREF=gi:6138971 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2 NM_001619 adrenergic, beta, receptor kinase 1 ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from sequence or structural similarity /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 201403_s_at NM_004528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004528.1 /DEF=Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA. /FEA=mRNA /GEN=MGST3 /PROD=microsomal glutathione S-transferase 3 /DB_XREF=gi:4758713 /UG=Hs.111811 microsomal glutathione S-transferase 3 /FL=gb:BC000505.1 gb:BC003034.1 gb:AF026977.1 gb:NM_004528.1 NM_004528 microsomal glutathione S-transferase 3 MGST3 4259 NM_004528 /// XM_005245174 0006629 // lipid metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // not recorded /// 0055114 // oxidation-reduction process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005635 // nuclear envelope // not recorded /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // not recorded /// 0004601 // peroxidase activity // traceable author statement /// 0004602 // glutathione peroxidase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation 201404_x_at BC000268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000268.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, beta type, 2, clone MGC:1664, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:12653014 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1 BC000268 proteasome (prosome, macropain) subunit, beta type, 2 PSMB2 5690 NM_001199779 /// NM_001199780 /// NM_002794 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201405_s_at NM_006833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006833.1 /DEF=Homo sapiens COP9 subunit 6 (MOV34 homolog, 34 kD) (MOV34-34KD), mRNA. /FEA=mRNA /GEN=MOV34-34KD /PROD=COP9 subunit 6 (MOV34 homolog, 34 kD) /DB_XREF=gi:5803095 /UG=Hs.15591 COP9 subunit 6 (MOV34 homolog, 34 kD) /FL=gb:BC002520.1 gb:U70735.1 gb:NM_006833.1 NM_006833 COP9 signalosome subunit 6 COPS6 10980 NM_006833 0010388 // cullin deneddylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201406_at NM_021029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021029.1 /DEF=Homo sapiens ribosomal protein L44 (RPL44), mRNA. /FEA=mRNA /GEN=RPL44 /PROD=ribosomal protein L44 /DB_XREF=gi:10445222 /UG=Hs.178391 ribosomal protein L44 /FL=gb:NM_021029.1 gb:BC001781.1 NM_021029 ribosomal protein L36a /// RPL36A-HNRNPH2 readthrough RPL36A /// RPL36A-HNRNPH2 6173 /// 100529097 NM_001199972 /// NM_001199973 /// NM_001199974 /// NM_021029 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201407_s_at AI186712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186712 /FEA=EST /DB_XREF=gi:3737350 /DB_XREF=est:qe82f01.x1 /CLONE=IMAGE:1745497 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 AI186712 protein phosphatase 1, catalytic subunit, beta isozyme PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201408_at W67887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W67887 /FEA=EST /DB_XREF=gi:1376776 /DB_XREF=est:zd38c11.s1 /CLONE=IMAGE:342932 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 W67887 protein phosphatase 1, catalytic subunit, beta isozyme PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201409_s_at NM_002709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002709.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), mRNA. /FEA=mRNA /GEN=PPP1CB /PROD=protein phosphatase 1, catalytic subunit, betaisoform /DB_XREF=gi:4506004 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 NM_002709 protein phosphatase 1, catalytic subunit, beta isozyme PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201410_at AI983043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983043 /FEA=EST /DB_XREF=gi:5810262 /DB_XREF=est:wz30b11.x1 /CLONE=IMAGE:2559549 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1 AI983043 pleckstrin homology domain containing, family B (evectins) member 2 PLEKHB2 55041 NM_001031706 /// NM_001100623 /// NM_001267062 /// NM_001267063 /// NM_001267064 /// NM_001267065 /// NM_001267066 /// NM_001267067 /// NM_001267068 /// NM_017958 /// NR_049789 /// NR_049790 /// NR_049791 /// NR_049792 /// XM_006712607 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 201411_s_at NM_017958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017958.1 /DEF=Homo sapiens hypothetical protein FLJ20783 (FLJ20783), mRNA. /FEA=mRNA /GEN=FLJ20783 /PROD=hypothetical protein FLJ20783 /DB_XREF=gi:8923679 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1 NM_017958 pleckstrin homology domain containing, family B (evectins) member 2 PLEKHB2 55041 NM_001031706 /// NM_001100623 /// NM_001267062 /// NM_001267063 /// NM_001267064 /// NM_001267065 /// NM_001267066 /// NM_001267067 /// NM_001267068 /// NM_017958 /// NR_049789 /// NR_049790 /// NR_049791 /// NR_049792 /// XM_006712607 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 201412_at NM_014045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014045.1 /DEF=Homo sapiens DKFZP564C1940 protein (DKFZP564C1940), mRNA. /FEA=mRNA /GEN=DKFZP564C1940 /PROD=DKFZP564C1940 protein /DB_XREF=gi:13027587 /UG=Hs.3804 DKFZP564C1940 protein /FL=gb:BC000424.1 gb:NM_014045.1 gb:AF131760.1 NM_014045 low density lipoprotein receptor-related protein 10 LRP10 26020 NM_014045 /// XM_005267510 0006897 // endocytosis // inferred from electronic annotation 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201413_at NM_000414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000414.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 4 (HSD17B4), mRNA. /FEA=mRNA /GEN=HSD17B4 /PROD=hydroxysteroid (17-beta) dehydrogenase 4 /DB_XREF=gi:4504504 /UG=Hs.75441 hydroxysteroid (17-beta) dehydrogenase 4 /FL=gb:BC003098.1 gb:NM_000414.1 NM_000414 hydroxysteroid (17-beta) dehydrogenase 4 HSD17B4 3295 NM_000414 /// NM_001199291 /// NM_001199292 /// NM_001292027 /// NM_001292028 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0036111 // very long-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0036112 // medium-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0060009 // Sertoli cell development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from direct assay /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from mutant phenotype /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from direct assay /// 0016508 // long-chain-enoyl-CoA hydratase activity // traceable author statement /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation /// 0033989 // 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044594 // 17-beta-hydroxysteroid dehydrogenase (NAD+) activity // inferred from direct assay 201414_s_at NM_005969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005969.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 4 (NAP1L4), mRNA. /FEA=mRNA /GEN=NAP1L4 /PROD=nucleosome assembly protein 1-like 4 /DB_XREF=gi:5174612 /UG=Hs.78103 nucleosome assembly protein 1-like 4 /FL=gb:U77456.1 gb:NM_005969.1 NM_005969 nucleosome assembly protein 1-like 4 NAP1L4 4676 NM_005969 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 201415_at NM_000178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000178.1 /DEF=Homo sapiens glutathione synthetase (GSS), mRNA. /FEA=mRNA /GEN=GSS /PROD=glutathione synthetase /DB_XREF=gi:4504168 /UG=Hs.82327 glutathione synthetase /FL=gb:U34683.1 gb:NM_000178.1 NM_000178 glutathione synthetase GSS 2937 NM_000178 /// XM_005260406 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004363 // glutathione synthase activity // traceable author statement /// 0005524 // ATP binding // inferred from direct assay /// 0016594 // glycine binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201416_at BG528420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG528420 /FEA=EST /DB_XREF=gi:13519957 /DB_XREF=est:602579853F1 /CLONE=IMAGE:4719060 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 BG528420 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201417_at AL136179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136179 /DEF=Human DNA sequence from clone RP3-322L4 on chromosome 6. Contains the SOX4 gene for SRY (sex determining region Y)-box 4, a pseudogene similar to predicted fly, worm and yeast genes, ESTs, STSs, GSSs and four CpG islands /FEA=mRNA /DB_XREF=gi:8649149 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 AL136179 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201418_s_at NM_003107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003107.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 4 (SOX4), mRNA. /FEA=mRNA /GEN=SOX4 /PROD=SRY (sex determining region Y)-box 4 /DB_XREF=gi:4507162 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 NM_003107 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201419_at NM_004656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004656.1 /DEF=Homo sapiens BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1), mRNA. /FEA=mRNA /GEN=BAP1 /PROD=BRCA1 associated protein-1 (ubiquitincarboxy-terminal hydrolase) /DB_XREF=gi:4757835 /UG=Hs.106674 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) /FL=gb:BC001596.1 gb:AF045581.1 gb:NM_004656.1 NM_004656 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) BAP1 8314 NM_004656 0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from direct assay /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0071108 // protein K48-linked deubiquitination // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035517 // PR-DUB complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // non-traceable author statement /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201420_s_at BF975273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF975273 /FEA=EST /DB_XREF=gi:12342488 /DB_XREF=est:602244783F1 /CLONE=IMAGE:4335765 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1 BF975273 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from genetic interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from genetic interaction /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034709 // methylosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from genetic interaction 201421_s_at NM_024102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024102.1 /DEF=Homo sapiens hypothetical protein MGC2722 (MGC2722), mRNA. /FEA=mRNA /GEN=MGC2722 /PROD=hypothetical protein MGC2722 /DB_XREF=gi:13129109 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1 NM_024102 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from genetic interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from genetic interaction /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034709 // methylosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from genetic interaction 201422_at NM_006332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006332.1 /DEF=Homo sapiens interferon, gamma-inducible protein 30 (IFI30), mRNA. /FEA=mRNA /GEN=IFI30 /PROD=interferon, gamma-inducible protein 30 /DB_XREF=gi:5453695 /UG=Hs.14623 interferon, gamma-inducible protein 30 /FL=gb:J03909.1 gb:NM_006332.1 gb:AF097362.1 NM_006332 interferon, gamma-inducible protein 30 /// phosphoinositide-3-kinase, regulatory subunit 2 (beta) IFI30 /// PIK3R2 5296 /// 10437 NM_005027 /// NM_006332 /// NR_073517 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from sequence or structural similarity /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016667 // oxidoreductase activity, acting on a sulfur group of donors // inferred from mutant phenotype /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation 201423_s_at AL037208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037208 /FEA=EST /DB_XREF=gi:5406648 /DB_XREF=est:DKFZp564B1169_s1 /CLONE=DKFZp564B1169 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1 AL037208 cullin 4A CUL4A 8451 NM_001008895 /// NM_001278513 /// NM_001278514 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201424_s_at NM_003589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003589.1 /DEF=Homo sapiens cullin 4A (CUL4A), mRNA. /FEA=mRNA /GEN=CUL4A /PROD=cullin 4A /DB_XREF=gi:11140810 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1 NM_003589 cullin 4A CUL4A 8451 NM_001008895 /// NM_001278513 /// NM_001278514 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201425_at NM_000690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000690.1 /DEF=Homo sapiens aldehyde dehydrogenase 2, mitochondrial (ALDH2), mRNA. /FEA=mRNA /GEN=ALDH2 /PROD=aldehyde dehydrogenase 2, mitochondrial /DB_XREF=gi:4502032 /UG=Hs.195432 aldehyde dehydrogenase 2 family (mitochondrial) /FL=gb:BC002967.1 gb:NM_000690.1 NM_000690 aldehyde dehydrogenase 2 family (mitochondrial) ALDH2 217 NM_000690 /// NM_001204889 0005975 // carbohydrate metabolic process // traceable author statement /// 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // not recorded /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 201426_s_at AI922599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922599 /FEA=EST /DB_XREF=gi:5658563 /DB_XREF=est:wm90b11.x1 /CLONE=IMAGE:2443197 /UG=Hs.297753 vimentin /FL=gb:BC000163.2 gb:NM_003380.1 AI922599 vimentin VIM 7431 NM_003380 /// XM_006717500 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0045103 // intermediate filament-based process // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0060020 // Bergmann glial cell differentiation // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005882 // intermediate filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 201427_s_at NM_005410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005410.1 /DEF=Homo sapiens selenoprotein P, plasma, 1 (SEPP1), mRNA. /FEA=mRNA /GEN=SEPP1 /PROD=selenoprotein P precursor /DB_XREF=gi:4885590 /UG=Hs.3314 selenoprotein P, plasma, 1 /FL=gb:NM_005410.1 NM_005410 selenoprotein P, plasma, 1 SEPP1 6414 NM_001085486 /// NM_001093726 /// NM_005410 0001887 // selenium compound metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008430 // selenium binding // inferred from electronic annotation 201428_at NM_001305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001305.1 /DEF=Homo sapiens claudin 4 (CLDN4), mRNA. /FEA=mRNA /GEN=CLDN4 /PROD=claudin 4 /DB_XREF=gi:4502876 /UG=Hs.5372 claudin 4 /FL=gb:BC000671.1 gb:AB000712.1 gb:NM_001305.1 NM_001305 claudin 4 CLDN4 1364 NM_001305 0007165 // signal transduction // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 201429_s_at NM_000998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000998.1 /DEF=Homo sapiens ribosomal protein L37a (RPL37A), mRNA. /FEA=mRNA /GEN=RPL37A /PROD=ribosomal protein L37a /DB_XREF=gi:4506642 /UG=Hs.5566 ribosomal protein L37a /FL=gb:BC000555.1 gb:L06499.1 gb:NM_000998.1 NM_000998 ribosomal protein L37a RPL37A 6168 NM_000998 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201430_s_at W72516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W72516 /FEA=EST /DB_XREF=gi:1382173 /DB_XREF=est:zd64g05.s1 /CLONE=IMAGE:345464 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1 W72516 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001197294 /// NM_001387 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from electronic annotation 201431_s_at NM_001387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001387.1 /DEF=Homo sapiens dihydropyrimidinase-like 3 (DPYSL3), mRNA. /FEA=mRNA /GEN=DPYSL3 /PROD=dihydropyrimidinase-like 3 /DB_XREF=gi:4503378 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1 NM_001387 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001197294 /// NM_001387 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from electronic annotation 201432_at NM_001752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001752.1 /DEF=Homo sapiens catalase (CAT), mRNA. /FEA=mRNA /GEN=CAT /PROD=catalase /DB_XREF=gi:4557013 /UG=Hs.76359 catalase /FL=gb:NM_001752.1 NM_001752 catalase CAT 847 NM_001752 0000302 // response to reactive oxygen species // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042697 // menopause // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0004096 // catalase activity // inferred from direct assay /// 0004096 // catalase activity // traceable author statement /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay 201433_s_at NM_014754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014754.1 /DEF=Homo sapiens phosphatidylserine synthase 1 (PTDSS1), mRNA. /FEA=mRNA /GEN=PTDSS1 /PROD=phosphatidylserine synthase 1 /DB_XREF=gi:7662646 /UG=Hs.77329 phosphatidylserine synthase 1 /FL=gb:BC004192.1 gb:BC004390.1 gb:D14694.1 gb:NM_014754.1 NM_014754 phosphatidylserine synthase 1 PTDSS1 9791 NM_001290225 /// NM_014754 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006659 // phosphatidylserine biosynthetic process // inferred from electronic annotation /// 0006659 // phosphatidylserine biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation 201434_at NM_003314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003314.1 /DEF=Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA. /FEA=mRNA /GEN=TTC1 /PROD=tetratricopeptide repeat domain 1 /DB_XREF=gi:4507710 /UG=Hs.7733 tetratricopeptide repeat domain 1 /FL=gb:BC000942.1 gb:U46570.1 gb:NM_003314.1 NM_003314 tetratricopeptide repeat domain 1 TTC1 7265 NM_001282500 /// NM_003314 0006457 // protein folding // non-traceable author statement 0005778 // peroxisomal membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 201435_s_at AW268640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW268640 /FEA=EST /DB_XREF=gi:6655670 /DB_XREF=est:xv52a03.x1 /CLONE=IMAGE:2816716 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AW268640 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201436_at AI742789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742789 /FEA=EST /DB_XREF=gi:5111077 /DB_XREF=est:wg46c05.x1 /CLONE=IMAGE:2368136 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AI742789 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201437_s_at NM_001968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001968.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), mRNA. /FEA=mRNA /GEN=EIF4E /PROD=eukaryotic translation initiation factor 4E /DB_XREF=gi:4503534 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 NM_001968 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201438_at NM_004369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004369.1 /DEF=Homo sapiens collagen, type VI, alpha 3 (COL6A3), mRNA. /FEA=mRNA /GEN=COL6A3 /PROD=collagen, type VI, alpha 3 /DB_XREF=gi:4758027 /UG=Hs.80988 collagen, type VI, alpha 3 /FL=gb:NM_004369.1 NM_004369 collagen, type VI, alpha 3 COL6A3 1293 NM_004369 /// NM_057164 /// NM_057165 /// NM_057166 /// NM_057167 /// XM_005246065 /// XM_005246066 /// XM_006712253 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 201439_at NM_004193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004193.1 /DEF=Homo sapiens golgi-specific brefeldin A resistance factor 1 (GBF1), mRNA. /FEA=mRNA /GEN=GBF1 /PROD=golgi-specific brefeldin A resistance factor 1 /DB_XREF=gi:4758415 /UG=Hs.155499 golgi-specific brefeldin A resistance factor 1 /FL=gb:AF068755.1 gb:NM_004193.1 NM_004193 golgi brefeldin A resistant guanine nucleotide exchange factor 1 GBF1 8729 NM_001199378 /// NM_001199379 /// NM_004193 /// XM_005270261 /// XM_006718047 /// XM_006718048 /// XM_006718049 /// XM_006718050 /// XM_006718051 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201440_at NM_004818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004818.1 /DEF=Homo sapiens prp28, U5 snRNP 100 kd protein (U5-100K), mRNA. /FEA=mRNA /GEN=U5-100K /PROD=prp28, U5 snRNP 100 kd protein /DB_XREF=gi:4759277 /UG=Hs.168103 prp28, U5 snRNP 100 kd protein /FL=gb:BC002366.1 gb:AF026402.1 gb:NM_004818.1 NM_004818 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 DDX23 9416 NM_004818 /// XM_006719699 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201441_at NM_001863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001863.2 /DEF=Homo sapiens cytochrome c oxidase subunit VIb (COX6B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6B /PROD=cytochrome c oxidase subunit VIb /DB_XREF=gi:6680989 /UG=Hs.174031 cytochrome c oxidase subunit VIb /FL=gb:BC001015.1 gb:BC002478.1 gb:NM_001863.2 NM_001863 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) COX6B1 1340 NM_001863 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // non-traceable author statement 201442_s_at AF248966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 AF248966 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201443_s_at AF248966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 AF248966 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201444_s_at NM_005765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005765.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 (APT6M8-9), mRNA. /FEA=mRNA /GEN=APT6M8-9 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) membrane sector associated protein M8-9 /DB_XREF=gi:5031590 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 NM_005765 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201445_at NM_001839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001839.1 /DEF=Homo sapiens calponin 3, acidic (CNN3), mRNA. /FEA=mRNA /GEN=CNN3 /PROD=calponin 3 /DB_XREF=gi:4502922 /UG=Hs.194662 calponin 3, acidic /FL=gb:NM_001839.1 NM_001839 calponin 3, acidic CNN3 1266 NM_001286055 /// NM_001286056 /// NM_001839 /// XM_006710335 0006939 // smooth muscle contraction // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from electronic annotation 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // non-traceable author statement /// 0008017 // microtubule binding // inferred from electronic annotation /// 0030172 // troponin C binding // non-traceable author statement 201446_s_at BF692742 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF692742 /FEA=EST /DB_XREF=gi:11978150 /DB_XREF=est:602079823F1 /CLONE=IMAGE:4244524 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 BF692742 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201447_at H96549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H96549 /FEA=EST /DB_XREF=gi:1110035 /DB_XREF=est:yw01c09.s1 /CLONE=IMAGE:250960 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 H96549 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201448_at AL046419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046419 /FEA=EST /DB_XREF=gi:5434493 /DB_XREF=est:DKFZp434N247_s1 /CLONE=DKFZp434N247 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL046419 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201449_at AL567227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567227 /FEA=EST /DB_XREF=gi:12920378 /DB_XREF=est:AL567227 /CLONE=CS0DF027YA11 (3 prime) /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL567227 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201450_s_at NM_022037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022037.1 /DEF=Homo sapiens TIA1 cytotoxic granule-associated RNA-binding protein (TIA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TIA1 /PROD=TIA1 protein, isoform 1 /DB_XREF=gi:11863160 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 NM_022037 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201451_x_at D78132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D78132.1 /DEF=Homo sapiens mRNA for ras-related GTP-binding protein, complete cds. /FEA=mRNA /GEN=Rheb /PROD=ras-related GTP-binding protein /DB_XREF=gi:1772344 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 D78132 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201452_at AW138374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138374 /FEA=EST /DB_XREF=gi:6142692 /DB_XREF=est:UI-H-BI1-adb-e-09-0-UI.s1 /CLONE=IMAGE:2716145 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 AW138374 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201453_x_at NM_005614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005614.1 /DEF=Homo sapiens Ras homolog enriched in brain 2 (RHEB2), mRNA. /FEA=mRNA /GEN=RHEB2 /PROD=Ras homolog enriched in brain 2 /DB_XREF=gi:5032040 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 NM_005614 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201454_s_at AW055008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW055008 /FEA=EST /DB_XREF=gi:5920711 /DB_XREF=est:wy98c09.x1 /CLONE=IMAGE:2556592 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1 AW055008 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 /// XM_006722187 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201455_s_at AJ132583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ132583.1 /DEF=Homo sapiens mRNA for puromycin sensitive aminopeptidase, partial. /FEA=mRNA /PROD=puromycin sensitive aminopeptidase /DB_XREF=gi:4210725 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1 AJ132583 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 /// XM_006722187 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201456_s_at AU160695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU160695 /FEA=EST /DB_XREF=gi:11022216 /DB_XREF=est:AU160695 /CLONE=Y79AA1002240 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 AU160695 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 201457_x_at AF081496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081496.1 /DEF=Homo sapiens kinetochore protein BUB3 (BUB3) mRNA, complete cds. /FEA=mRNA /GEN=BUB3 /PROD=kinetochore protein BUB3 /DB_XREF=gi:3639059 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 AF081496 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 201458_s_at NM_004725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004725.1 /DEF=Homo sapiens BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog (BUB3), mRNA. /FEA=mRNA /GEN=BUB3 /PROD=BUB3 (budding uninhibited by benzimidazoles 3,yeast) homolog /DB_XREF=gi:4757879 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 NM_004725 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 201459_at NM_006666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006666.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 2 (RUVBL2), mRNA. /FEA=mRNA /GEN=RUVBL2 /PROD=RuvB (E coli homolog)-like 2 /DB_XREF=gi:5730022 /UG=Hs.6455 RuvB (E coli homolog)-like 2 /FL=gb:BC000428.1 gb:BC004531.1 gb:AB024301.1 gb:AF151804.1 gb:AF155138.1 gb:NM_006666.1 gb:AL136743.1 gb:AF124607.1 NM_006666 RuvB-like AAA ATPase 2 RUVBL2 10856 NM_006666 /// XM_005258426 /// XM_005258427 /// XM_005258428 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from mutant phenotype /// 0071733 // transcriptional activation by promoter-enhancer looping // inferred from mutant phenotype /// 0071899 // negative regulation of estrogen receptor binding // inferred from mutant phenotype 0000812 // Swr1 complex // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 201460_at AI141802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI141802 /FEA=EST /DB_XREF=gi:3649259 /DB_XREF=est:qa56e05.s1 /CLONE=IMAGE:1690784 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1 AI141802 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 /// XM_005273353 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032675 // regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 201461_s_at NM_004759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004759.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), mRNA. /FEA=mRNA /GEN=MAPKAPK2 /PROD=mitogen-activated protein kinase-activatedprotein kinase 2 /DB_XREF=gi:10863900 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1 NM_004759 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 /// XM_005273353 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032675 // regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 201462_at NM_014766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014766.1 /DEF=Homo sapiens KIAA0193 gene product (KIAA0193), mRNA. /FEA=mRNA /GEN=KIAA0193 /PROD=KIAA0193 gene product /DB_XREF=gi:7661983 /UG=Hs.75137 KIAA0193 gene product /FL=gb:D83777.1 gb:NM_014766.1 NM_014766 secernin 1 SCRN1 9805 NM_001145513 /// NM_001145514 /// NM_001145515 /// NM_014766 /// XM_005249918 0006508 // proteolysis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0016805 // dipeptidase activity // inferred from electronic annotation 201463_s_at NM_006755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006755.1 /DEF=Homo sapiens transaldolase 1 (TALDO1), mRNA. /FEA=mRNA /GEN=TALDO1 /PROD=transaldolase 1 /DB_XREF=gi:5803186 /UG=Hs.77290 transaldolase 1 /FL=gb:L19437.2 gb:NM_006755.1 NM_006755 transaldolase 1 TALDO1 6888 NM_006755 0005975 // carbohydrate metabolic process // traceable author statement /// 0005999 // xylulose biosynthetic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004801 // sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 201464_x_at BG491844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG491844 /FEA=EST /DB_XREF=gi:13453356 /DB_XREF=est:602535931T1 /CLONE=IMAGE:4684998 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 BG491844 jun proto-oncogene JUN 3725 NM_002228 0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201465_s_at BC002646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002646.1 /DEF=Homo sapiens, v-jun avian sarcoma virus 17 oncogene homolog, clone MGC:3338, mRNA, complete cds. /FEA=mRNA /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:12803622 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 BC002646 jun proto-oncogene JUN 3725 NM_002228 0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201466_s_at NM_002228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002228.2 /DEF=Homo sapiens v-jun avian sarcoma virus 17 oncogene homolog (JUN), mRNA. /FEA=mRNA /GEN=JUN /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:7710122 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 NM_002228 jun proto-oncogene JUN 3725 NM_002228 0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201467_s_at AI039874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI039874 /FEA=EST /DB_XREF=gi:3279068 /DB_XREF=est:ox97c05.x1 /CLONE=IMAGE:1664264 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1 AI039874 NAD(P)H dehydrogenase, quinone 1 NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 /// NM_001286137 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201468_s_at NM_000903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000903.1 /DEF=Homo sapiens diaphorase (NADHNADPH) (cytochrome b-5 reductase) (DIA4), mRNA. /FEA=mRNA /GEN=DIA4 /PROD=NAD(P)H menadione oxidoreductase 1,dioxin-inducible /DB_XREF=gi:4505414 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1 NM_000903 NAD(P)H dehydrogenase, quinone 1 NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 /// NM_001286137 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201469_s_at AI809967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI809967 /FEA=EST /DB_XREF=gi:5396533 /DB_XREF=est:wf64c03.x1 /CLONE=IMAGE:2360356 /UG=Hs.81972 SHC (Src homology 2 domain-containing) transforming protein 1 /FL=gb:NM_003029.1 gb:U73377.1 AI809967 SHC (Src homology 2 domain containing) transforming protein 1 SHC1 6464 NM_001130040 /// NM_001130041 /// NM_001202859 /// NM_003029 /// NM_183001 /// XM_005245449 /// XM_005245450 /// XM_005245451 /// XM_005245452 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 201470_at NM_004832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004832.1 /DEF=Homo sapiens glutathione-S-transferase like; glutathione transferase omega (GSTTLp28), mRNA. /FEA=mRNA /GEN=GSTTLp28 /PROD=glutathione-S-transferase like /DB_XREF=gi:4758483 /UG=Hs.11465 glutathione-S-transferase like; glutathione transferase omega /FL=gb:BC000127.1 gb:U90313.1 gb:NM_004832.1 gb:AF212303.1 NM_004832 glutathione S-transferase omega 1 GSTO1 9446 NM_001191002 /// NM_001191003 /// NM_004832 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0014810 // positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred by curator /// 0019852 // L-ascorbic acid metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0045174 // glutathione dehydrogenase (ascorbate) activity // inferred from direct assay /// 0050610 // methylarsonate reductase activity // inferred from electronic annotation 201471_s_at NM_003900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003900.1 /DEF=Homo sapiens sequestosome 1 (SQSTM1), mRNA. /FEA=mRNA /GEN=SQSTM1 /PROD=sequestosome 1 /DB_XREF=gi:4505570 /UG=Hs.182248 sequestosome 1 /FL=gb:U41806.1 gb:BC003139.1 gb:U46751.1 gb:NM_003900.1 NM_003900 sequestosome 1 SQSTM1 8878 NM_001142298 /// NM_001142299 /// NM_003900 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006914 // autophagy // inferred from mutant phenotype /// 0006914 // autophagy // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0008104 // protein localization // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0016236 // macroautophagy // inferred from sequence or structural similarity /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from electronic annotation 201472_at NM_003372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003372.2 /DEF=Homo sapiens von Hippel-Lindau binding protein 1 (VBP1), mRNA. /FEA=mRNA /GEN=VBP1 /PROD=von Hippel-Lindau binding protein 1 /DB_XREF=gi:9257253 /UG=Hs.198307 von Hippel-Lindau binding protein 1 /FL=gb:U96759.1 gb:NM_003372.2 NM_003372 von Hippel-Lindau binding protein 1 VBP1 7411 NM_003372 /// XM_005274729 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016272 // prefoldin complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 201473_at NM_002229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002229.1 /DEF=Homo sapiens jun B proto-oncogene (JUNB), mRNA. /FEA=mRNA /GEN=JUNB /PROD=jun B proto-oncogene /DB_XREF=gi:4504808 /UG=Hs.198951 jun B proto-oncogene /FL=gb:BC004250.1 gb:NM_002229.1 NM_002229 jun B proto-oncogene JUNB 3726 NM_002229 0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033687 // osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046697 // decidualization // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201474_s_at NM_002204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002204.1 /DEF=Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant a, mRNA. /FEA=mRNA /GEN=ITGA3 /PROD=integrin alpha 3 isoform a precursor /DB_XREF=gi:4504746 /UG=Hs.265829 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) /FL=gb:M59911.1 gb:NM_002204.1 NM_002204 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) ITGA3 3675 NM_002204 /// NM_005501 /// XM_005257308 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201475_x_at NM_004990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004990.1 /DEF=Homo sapiens methionine-tRNA synthetase (MARS), mRNA. /FEA=mRNA /GEN=MARS /PROD=methionine-tRNA synthetase /DB_XREF=gi:4826825 /UG=Hs.279946 methionine-tRNA synthetase /FL=gb:BC002384.1 gb:NM_004990.1 gb:D84224.1 NM_004990 methionyl-tRNA synthetase /// microRNA 6758 MARS /// MIR6758 4141 /// 102465454 NM_004990 /// NR_106816 /// XM_006719398 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006431 // methionyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004825 // methionine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201476_s_at AI692974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI692974 /FEA=EST /DB_XREF=gi:4970314 /DB_XREF=est:wd36e03.x1 /CLONE=IMAGE:2330236 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1 AI692974 ribonucleotide reductase M1 RRM1 6240 NM_001033 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation 201477_s_at NM_001033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001033.1 /DEF=Homo sapiens ribonucleotide reductase M1 polypeptide (RRM1), mRNA. /FEA=mRNA /GEN=RRM1 /PROD=ribonucleotide reductase M1 polypeptide /DB_XREF=gi:4506748 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1 NM_001033 ribonucleotide reductase M1 RRM1 6240 NM_001033 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation 201478_s_at U59151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59151.1 /DEF=Human Cbf5p homolog (CBF5) mRNA, complete cds. /FEA=mRNA /GEN=CBF5 /PROD=Cbf5p homolog /DB_XREF=gi:2737893 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1 U59151 dyskeratosis congenita 1, dyskerin /// microRNA 664b /// small nucleolar RNA, H/ACA box 56 DKC1 /// MIR664B /// SNORA56 1736 /// 677835 /// 100847052 NM_001142463 /// NM_001288747 /// NM_001363 /// NR_002984 /// NR_049842 /// NR_110021 /// NR_110022 /// NR_110023 0000723 // telomere maintenance // traceable author statement /// 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201479_at NM_001363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001363.1 /DEF=Homo sapiens dyskeratosis congenita 1, dyskerin (DKC1), mRNA. /FEA=mRNA /GEN=DKC1 /PROD=dyskeratosis congenita 1, dyskerin /DB_XREF=gi:4503336 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1 NM_001363 dyskeratosis congenita 1, dyskerin /// microRNA 664b /// small nucleolar RNA, H/ACA box 56 DKC1 /// MIR664B /// SNORA56 1736 /// 677835 /// 100847052 NM_001142463 /// NM_001288747 /// NM_001363 /// NR_002984 /// NR_049842 /// NR_110021 /// NR_110022 /// NR_110023 0000723 // telomere maintenance // traceable author statement /// 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201480_s_at NM_003169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003169.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 5 homolog (SUPT5H), mRNA. /FEA=mRNA /GEN=SUPT5H /PROD=suppressor of Ty (S.cerevisiae) 5 homolog /DB_XREF=gi:4507312 /UG=Hs.70186 suppressor of Ty (S.cerevisiae) 5 homolog /FL=gb:U56402.1 gb:AB000516.1 gb:NM_003169.1 NM_003169 suppressor of Ty 5 homolog (S. cerevisiae) SUPT5H 6829 NM_001111020 /// NM_001130824 /// NM_001130825 /// NM_003169 /// XM_005259183 /// XM_006723337 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0010033 // response to organic substance // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0039692 // single stranded viral RNA replication via double stranded DNA intermediate // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0032044 // DSIF complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201481_s_at NM_002862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002862.1 /DEF=Homo sapiens phosphorylase, glycogen; brain (PYGB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PYGB /PROD=phosphorylase, glycogen; brain /DB_XREF=gi:4506350 /UG=Hs.75658 phosphorylase, glycogen; brain /FL=gb:U47025.1 gb:NM_002862.1 NM_002862 phosphorylase, glycogen; brain PYGB 5834 NM_002862 /// XM_006723601 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // non-traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0008184 // glycogen phosphorylase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 201482_at NM_002826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002826.2 /DEF=Homo sapiens quiescin Q6 (QSCN6), mRNA. /FEA=mRNA /GEN=QSCN6 /PROD=quiescin Q6 /DB_XREF=gi:13325074 /UG=Hs.77266 quiescin Q6 /FL=gb:L42379.1 gb:U97276.2 gb:NM_002826.2 NM_002826 quiescin Q6 sulfhydryl oxidase 1 QSOX1 5768 NM_001004128 /// NM_002826 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // inferred from genetic interaction /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0003756 // protein disulfide isomerase activity // inferred from genetic interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016971 // flavin-linked sulfhydryl oxidase activity // inferred from direct assay /// 0016971 // flavin-linked sulfhydryl oxidase activity // inferred from genetic interaction /// 0016972 // thiol oxidase activity // inferred from electronic annotation 201483_s_at BC002802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002802.1 /DEF=Homo sapiens, suppressor of Ty (S.cerevisiae) 4 homolog 1, clone MGC:3864, mRNA, complete cds. /FEA=mRNA /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:12803910 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1 BC002802 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 /// NR_073470 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032044 // DSIF complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201484_at NM_003168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003168.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 4 homolog 1 (SUPT4H1), mRNA. /FEA=mRNA /GEN=SUPT4H1 /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:4507310 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1 NM_003168 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 /// NR_073470 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032044 // DSIF complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201485_s_at BC004892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004892.1 /DEF=Homo sapiens, reticulocalbin 2, EF-hand calcium binding domain, clone MGC:1650, mRNA, complete cds. /FEA=mRNA /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:13436151 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1 BC004892 reticulocalbin 2, EF-hand calcium binding domain RCN2 5955 NM_001271837 /// NM_002902 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201486_at NM_002902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002902.1 /DEF=Homo sapiens reticulocalbin 2, EF-hand calcium binding domain (RCN2), mRNA. /FEA=mRNA /GEN=RCN2 /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:4506456 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1 NM_002902 reticulocalbin 2, EF-hand calcium binding domain RCN2 5955 NM_001271837 /// NM_002902 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201487_at NM_001814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001814.1 /DEF=Homo sapiens cathepsin C (CTSC), mRNA. /FEA=mRNA /GEN=CTSC /PROD=cathepsin C /DB_XREF=gi:4503140 /UG=Hs.10029 cathepsin C /FL=gb:NM_001814.1 NM_001814 cathepsin C CTSC 1075 NM_001114173 /// NM_001814 /// NM_148170 0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity 201488_x_at BC000717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000717.1 /DEF=Homo sapiens, GAP-associated tyrosine phosphoprotein p62 (Sam68), clone MGC:1286, mRNA, complete cds. /FEA=mRNA /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:12653852 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1 BC000717 KH domain containing, RNA binding, signal transduction associated 1 KHDRBS1 10657 NM_001271878 /// NM_006559 /// NR_073498 /// NR_073499 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0031647 // regulation of protein stability // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045948 // positive regulation of translational initiation // inferred from direct assay /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070618 // Grb2-Sos complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201489_at BC005020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005020.1 /DEF=Homo sapiens, peptidylprolyl isomerase F (cyclophilin F), clone MGC:11022, mRNA, complete cds. /FEA=mRNA /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:13477126 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1 BC005020 peptidylprolyl isomerase F PPIF 10105 NM_005729 /// XM_005269379 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010849 // regulation of proton-transporting ATPase activity, rotational mechanism // inferred from sequence or structural similarity /// 0010939 // regulation of necrotic cell death // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090324 // negative regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 1902445 // regulation of mitochondrial membrane permeability involved in programmed necrotic cell death // inferred from mutant phenotype /// 2000276 // negative regulation of oxidative phosphorylation uncoupler activity // inferred from sequence or structural similarity /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201490_s_at NM_005729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005729.1 /DEF=Homo sapiens peptidylprolyl isomerase F (cyclophilin F) (PPIF), mRNA. /FEA=mRNA /GEN=PPIF /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:5031986 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1 NM_005729 peptidylprolyl isomerase F PPIF 10105 NM_005729 /// XM_005269379 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010849 // regulation of proton-transporting ATPase activity, rotational mechanism // inferred from sequence or structural similarity /// 0010939 // regulation of necrotic cell death // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090324 // negative regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 1902445 // regulation of mitochondrial membrane permeability involved in programmed necrotic cell death // inferred from mutant phenotype /// 2000276 // negative regulation of oxidative phosphorylation uncoupler activity // inferred from sequence or structural similarity /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201491_at NM_012111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012111.1 /DEF=Homo sapiens chromosome 14 open reading frame 3 (C14ORF3), mRNA. /FEA=mRNA /GEN=C14ORF3 /PROD=chromosome 14 open reading frame 3 /DB_XREF=gi:6912279 /UG=Hs.204041 chromosome 14 open reading frame 3 /FL=gb:BC000321.1 gb:NM_012111.1 gb:AF164791.1 NM_012111 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) AHSA1 10598 NM_012111 0006457 // protein folding // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay 201492_s_at NM_021104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021104.1 /DEF=Homo sapiens ribosomal protein L41 (RPL41), mRNA. /FEA=mRNA /GEN=RPL41 /PROD=ribosomal protein L41 /DB_XREF=gi:10863874 /UG=Hs.324406 ribosomal protein L41 /FL=gb:NM_021104.1 NM_021104 ribosomal protein L41 RPL41 6171 NM_001035267 /// NM_021104 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 201493_s_at BE778078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE778078 /FEA=EST /DB_XREF=gi:10199276 /DB_XREF=est:601463189F1 /CLONE=IMAGE:3866399 /UG=Hs.6151 pumilio (Drosophila) homolog 2 /FL=gb:AF315591.1 gb:NM_015317.1 BE778078 pumilio RNA-binding family member 2 PUM2 23369 NM_001282752 /// NM_001282790 /// NM_001282791 /// NM_015317 /// XM_005262607 /// XM_005262609 /// XM_005262610 /// XM_006711972 /// XM_006711973 /// XM_006711974 /// XM_006711975 0006417 // regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201494_at NM_005040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005040.1 /DEF=Homo sapiens prolylcarboxypeptidase (angiotensinase C) (PRCP), mRNA. /FEA=mRNA /GEN=PRCP /PROD=prolylcarboxypeptidase (angiotensinase C) /DB_XREF=gi:4826939 /UG=Hs.75693 prolylcarboxypeptidase (angiotensinase C) /FL=gb:L13977.1 gb:NM_005040.1 NM_005040 prolylcarboxypeptidase (angiotensinase C) PRCP 5547 NM_005040 /// NM_199418 /// XM_005274093 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201495_x_at AI889739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI889739 /FEA=EST /DB_XREF=gi:5594903 /DB_XREF=est:wo17e08.x1 /CLONE=IMAGE:2455622 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 AI889739 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0051015 // actin filament binding // inferred from electronic annotation 201496_x_at S67238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S67238.1 /DEF=smooth muscle myosin heavy chain isoform SM2 human, umbilical cord, fetal aorta, mRNA Partial, 1078 nt. /FEA=mRNA /GEN=smooth muscle myosin heavy chain isoform SM2 /PROD=smooth muscle myosin heavy chain isoform SM2 /DB_XREF=gi:452982 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 S67238 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0051015 // actin filament binding // inferred from electronic annotation 201497_x_at NM_022844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022844.1 /DEF=Homo sapiens myosin, heavy polypeptide 11, smooth muscle (MYH11), transcript variant SM2, mRNA. /FEA=mRNA /GEN=MYH11 /PROD=smooth muscle myosin heavy chain 11, isoformSM2 /DB_XREF=gi:13124874 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 NM_022844 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0030546 // receptor activator activity // inferred from electronic annotation /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0043539 // protein serine/threonine kinase activator activity // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from electronic annotation 201498_at AI160440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI160440 /FEA=EST /DB_XREF=gi:3693820 /DB_XREF=est:qc08f12.x1 /CLONE=IMAGE:1709039 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1 AI160440 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_001286457 /// NM_001286458 /// NM_003470 0006281 // DNA repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0002039 // p53 binding // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 201499_s_at NM_003470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003470.1 /DEF=Homo sapiens ubiquitin specific protease 7 (herpes virus-associated) (USP7), mRNA. /FEA=mRNA /GEN=USP7 /PROD=ubiquitin specific protease 7 (herpesvirus-associated) /DB_XREF=gi:4507856 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1 NM_003470 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_001286457 /// NM_001286458 /// NM_003470 0006281 // DNA repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0002039 // p53 binding // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 201500_s_at NM_021959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021959.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA. /FEA=mRNA /GEN=PPP1R11 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 11 /DB_XREF=gi:11386174 /UG=Hs.82887 protein phosphatase 1, regulatory (inhibitor) subunit 11 /FL=gb:NM_021959.1 NM_021959 protein phosphatase 1, regulatory (inhibitor) subunit 11 PPP1R11 6992 NM_021959 /// NM_170781 /// XM_005275158 /// XM_006715174 /// XM_006725042 /// XM_006725499 /// XM_006725713 /// XM_006725921 /// XM_006726016 /// XM_006726110 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201501_s_at NM_002092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002092.1 /DEF=Homo sapiens G-rich RNA sequence binding factor 1 (GRSF1), mRNA. /FEA=mRNA /GEN=GRSF1 /PROD=G-rich RNA sequence binding factor 1 /DB_XREF=gi:4504160 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1 NM_002092 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201502_s_at AI078167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI078167 /FEA=EST /DB_XREF=gi:3412575 /DB_XREF=est:oz30d08.x1 /CLONE=IMAGE:1676847 /UG=Hs.81328 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha /FL=gb:NM_020529.1 gb:BC002601.1 gb:BC004983.1 gb:M69043.1 AI078167 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha NFKBIA 4792 NM_020529 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007253 // cytoplasmic sequestering of NF-kappaB // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070417 // cellular response to cold // non-traceable author statement /// 0070427 // nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0033256 // I-kappaB/NF-kappaB complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0008139 // nuclear localization sequence binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 201503_at BG500067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG500067 /FEA=EST /DB_XREF=gi:13461584 /DB_XREF=est:602545874F1 /CLONE=IMAGE:4668234 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1 BG500067 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 /// XM_006714749 /// XM_006714750 0006200 // ATP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201504_s_at AI435302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI435302 /FEA=EST /DB_XREF=gi:4302230 /DB_XREF=est:ti02h06.x1 /CLONE=IMAGE:2129339 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI435302 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201505_at NM_002291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002291.1 /DEF=Homo sapiens laminin, beta 1 (LAMB1), mRNA. /FEA=mRNA /GEN=LAMB1 /PROD=laminin, beta 1 precursor /DB_XREF=gi:4504950 /UG=Hs.82124 laminin, beta 1 /FL=gb:M61916.1 gb:NM_002291.1 NM_002291 laminin, beta 1 LAMB1 3912 NM_002291 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021812 // neuronal-glial interaction involved in cerebral cortex radial glia guided migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042476 // odontogenesis // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from direct assay /// 0005606 // laminin-1 complex // inferred from physical interaction /// 0005606 // laminin-1 complex // traceable author statement /// 0005607 // laminin-2 complex // inferred from direct assay /// 0005607 // laminin-2 complex // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043256 // laminin complex // inferred from electronic annotation /// 0043257 // laminin-8 complex // inferred from direct assay /// 0043257 // laminin-8 complex // traceable author statement /// 0043259 // laminin-10 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 201506_at NM_000358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000358.1 /DEF=Homo sapiens transforming growth factor, beta-induced, 68kD (TGFBI), mRNA. /FEA=mRNA /GEN=TGFBI /PROD=transforming growth factor, beta-induced, 68kD /DB_XREF=gi:4507466 /UG=Hs.118787 transforming growth factor, beta-induced, 68kD /FL=gb:BC000097.1 gb:BC004972.1 gb:M77349.1 gb:NM_000358.1 NM_000358 transforming growth factor, beta-induced, 68kDa TGFBI 7045 NM_000358 0001525 // angiogenesis // inferred from expression pattern /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201507_at NM_002622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002622.2 /DEF=Homo sapiens prefoldin 1 (PFDN1), mRNA. /FEA=mRNA /GEN=PFDN1 /PROD=prefoldin 1 /DB_XREF=gi:12408673 /UG=Hs.132881 prefoldin 1 /FL=gb:NM_002622.2 NM_002622 prefoldin subunit 1 PFDN1 5201 NM_002622 /// XM_005268465 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0016272 // prefoldin complex // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 201508_at NM_001552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001552.1 /DEF=Homo sapiens insulin-like growth factor-binding protein 4 (IGFBP4), mRNA. /FEA=mRNA /GEN=IGFBP4 /PROD=insulin-like growth factor-binding protein 4 /DB_XREF=gi:10835020 /UG=Hs.1516 insulin-like growth factor-binding protein 4 /FL=gb:NM_001552.1 gb:M62403.1 NM_001552 insulin-like growth factor binding protein 4 IGFBP4 3487 NM_001552 0001501 // skeletal system development // traceable author statement /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201509_at NM_006899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006899.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), mRNA. /FEA=mRNA /GEN=IDH3B /PROD=isocitrate dehydrogenase 3 (NAD+) beta /DB_XREF=gi:5901981 /UG=Hs.155410 isocitrate dehydrogenase 3 (NAD+) beta /FL=gb:BC001960.1 gb:U49283.1 gb:NM_006899.1 NM_006899 isocitrate dehydrogenase 3 (NAD+) beta IDH3B 3420 NM_001258384 /// NM_006899 /// NM_174855 /// NM_174856 /// XM_005260716 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201510_at AF017307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF017307.1 /DEF=Homo sapiens Ets-related transcription factor (ERT) mRNA, complete cds. /FEA=mRNA /GEN=ERT /PROD=Ets-related transcription factor /DB_XREF=gi:2338755 /UG=Hs.166096 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) /FL=gb:BC003569.1 gb:U66894.1 gb:U73843.1 gb:AF017307.1 gb:AF016295.1 gb:U97156.1 gb:NM_004433.1 AF017307 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) ELF3 1999 NM_001114309 /// NM_004433 /// XM_005244942 0001824 // blastocyst development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // inferred from expression pattern /// 0007275 // multicellular organismal development // traceable author statement /// 0008544 // epidermis development // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201511_at NM_001087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001087.1 /DEF=Homo sapiens angio-associated, migratory cell protein (AAMP), mRNA. /FEA=mRNA /GEN=AAMP /PROD=angio-associated, migratory cell protein /DB_XREF=gi:4557228 /UG=Hs.83347 angio-associated, migratory cell protein /FL=gb:NM_001087.1 gb:M95627.1 NM_001087 angio-associated, migratory cell protein AAMP 14 NM_001087 /// XM_005246325 0001525 // angiogenesis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from sequence or structural similarity /// 0014909 // smooth muscle cell migration // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement 201512_s_at BC003633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003633.1 /DEF=Homo sapiens, translocase of outer mitochondrial membrane 70 (yeast) homolog A, clone MGC:3766, mRNA, complete cds. /FEA=mRNA /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:13177705 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1 BC003633 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201513_at AI659180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659180 /FEA=EST /DB_XREF=gi:4762750 /DB_XREF=est:tu02c06.x1 /CLONE=IMAGE:2249866 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI659180 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201514_s_at NM_005754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005754.1 /DEF=Homo sapiens Ras-GTPase-activating protein SH3-domain-binding protein (G3BP), mRNA. /FEA=mRNA /GEN=G3BP /PROD=Ras-GTPase-activating protein SH3-domain-bindingprotein /DB_XREF=gi:5031702 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1 NM_005754 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 /// XM_006714749 /// XM_006714750 0006200 // ATP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201515_s_at NM_004622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004622.1 /DEF=Homo sapiens translin (TSN), mRNA. /FEA=mRNA /GEN=TSN /PROD=translin /DB_XREF=gi:4759269 /UG=Hs.75066 translin /FL=gb:NM_004622.1 NM_004622 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201516_at NM_003132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003132.1 /DEF=Homo sapiens spermidine synthase (SRM), mRNA. /FEA=mRNA /GEN=SRM /PROD=spermidine synthase /DB_XREF=gi:4507208 /UG=Hs.76244 spermidine synthase /FL=gb:BC000309.1 gb:NM_003132.1 gb:M34338.1 NM_003132 spermidine synthase SRM 6723 NM_003132 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from direct assay /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004766 // spermidine synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 201517_at BC001255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001255.1 /DEF=Homo sapiens, nuclear cap binding protein subunit 2, 20kD, clone MGC:4991, mRNA, complete cds. /FEA=mRNA /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:12654824 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1 BC001255 nuclear cap binding protein subunit 2, 20kDa NCBP2 22916 NM_001042540 /// NM_007362 /// XM_005269313 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201518_at NM_006807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006807.1 /DEF=Homo sapiens chromobox homolog 1 (Drosophila HP1 beta) (CBX1), mRNA. /FEA=mRNA /GEN=CBX1 /PROD=chromobox homolog 1 (Drosophila HP1 beta) /DB_XREF=gi:5803075 /UG=Hs.77254 chromobox homolog 1 (Drosophila HP1 beta) /FL=gb:U35451.1 gb:BC002609.1 gb:NM_006807.1 NM_006807 chromobox homolog 1 CBX1 10951 NM_001127228 /// NM_006807 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 1990226 // histone methyltransferase binding // inferred from physical interaction 201519_at NM_014820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014820.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 70 (yeast) homolog A (TOMM70A), mRNA. /FEA=mRNA /GEN=TOMM70A /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:7662672 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1 NM_014820 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201520_s_at BF034561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF034561 /FEA=EST /DB_XREF=gi:10742273 /DB_XREF=est:601455476F1 /CLONE=IMAGE:3859242 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1 BF034561 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201521_s_at NM_007362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007362.1 /DEF=Homo sapiens nuclear cap binding protein subunit 2, 20kD (NCBP2), mRNA. /FEA=mRNA /GEN=NCBP2 /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:6679063 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1 NM_007362 nuclear cap binding protein subunit 2, 20kDa NCBP2 22916 NM_001042540 /// NM_007362 /// XM_005269313 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201522_x_at NM_003097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003097.2 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. /FEA=mRNA /GEN=SNRPN /PROD=small nuclear ribonucleoprotein polypeptide N /DB_XREF=gi:13027651 /UG=Hs.48375 small nuclear ribonucleoprotein polypeptide N /FL=gb:U41303.1 gb:NM_003097.2 gb:BC003180.1 gb:J04615.1 NM_003097 small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame SNRPN /// SNURF 6638 /// 8926 NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201523_x_at BE262760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE262760 /FEA=EST /DB_XREF=gi:9136144 /DB_XREF=est:601153762F1 /CLONE=IMAGE:3509895 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1 BE262760 ubiquitin-conjugating enzyme E2N UBE2N 7334 NM_003348 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201524_x_at NM_003348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003348.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) (UBE2N), mRNA. /FEA=mRNA /GEN=UBE2N /PROD=ubiquitin-conjugating enzyme E2N (homologous toyeast UBC13) /DB_XREF=gi:4507792 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1 NM_003348 ubiquitin-conjugating enzyme E2N UBE2N 7334 NM_003348 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201525_at NM_001647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001647.1 /DEF=Homo sapiens apolipoprotein D (APOD), mRNA. /FEA=mRNA /GEN=APOD /PROD=apolipoprotein D precursor /DB_XREF=gi:4502162 /UG=Hs.75736 apolipoprotein D /FL=gb:J02611.1 gb:NM_001647.1 NM_001647 apolipoprotein D APOD 347 NM_001647 0000302 // response to reactive oxygen species // inferred from direct assay /// 0001525 // angiogenesis // non-traceable author statement /// 0006006 // glucose metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // non-traceable author statement /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007568 // aging // non-traceable author statement /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014012 // peripheral nervous system axon regeneration // inferred from sequence or structural similarity /// 0030682 // evasion or tolerance of host defense response // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0042308 // negative regulation of protein import into nucleus // inferred from direct assay /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0060588 // negative regulation of lipoprotein lipid oxidation // inferred from direct assay /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900016 // negative regulation of cytokine production involved in inflammatory response // inferred from direct assay /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from mutant phenotype /// 2000405 // negative regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0022626 // cytosolic ribosome // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0036094 // small molecule binding // inferred from electronic annotation 201526_at NM_001662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001662.2 /DEF=Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA. /FEA=mRNA /GEN=ARF5 /PROD=ADP-ribosylation factor 5 /DB_XREF=gi:6995999 /UG=Hs.77541 ADP-ribosylation factor 5 /FL=gb:BC003043.1 gb:M57567.1 gb:NM_001662.2 NM_001662 ADP-ribosylation factor 5 ARF5 381 NM_001662 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201527_at NM_004231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004231.1 /DEF=Homo sapiens ATPase, vacuolar, 14 kD (ATP6S14), mRNA. /FEA=mRNA /GEN=ATP6S14 /PROD=ATPase, vacuolar, 14 kD /DB_XREF=gi:4757819 /UG=Hs.78089 ATPase, vacuolar, 14 kD /FL=gb:D49400.1 gb:NM_004231.1 NM_004231 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F /// V-type proton ATPase subunit F-like ATP6V1F /// LOC101927180 9296 /// 101927180 NM_001198909 /// NM_004231 /// XM_005269262 /// XM_005275720 /// XM_005276420 0006200 // ATP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016469 // proton-transporting two-sector ATPase complex // non-traceable author statement /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0042624 // ATPase activity, uncoupled // non-traceable author statement /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201528_at BG398414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG398414 /FEA=EST /DB_XREF=gi:13291862 /DB_XREF=est:602439888F1 /CLONE=IMAGE:4566380 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1 BG398414 replication protein A1, 70kDa RPA1 6117 NM_002945 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201529_s_at NM_002945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002945.1 /DEF=Homo sapiens replication protein A1 (70kD) (RPA1), mRNA. /FEA=mRNA /GEN=RPA1 /PROD=replication protein A1 (70kD) /DB_XREF=gi:4506582 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1 NM_002945 replication protein A1, 70kDa RPA1 6117 NM_002945 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201530_x_at NM_001416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001416.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA. /FEA=mRNA /GEN=EIF4A1 /PROD=eukaryotic translation initiation factor 4A,isoform 1 /DB_XREF=gi:4503528 /UG=Hs.129673 eukaryotic translation initiation factor 4A, isoform 1 /FL=gb:NM_001416.1 NM_001416 eukaryotic translation initiation factor 4A1 /// uncharacterized LOC101928634 /// SENP3-EIF4A1 readthrough (NMD candidate) /// small nucleolar RNA, H/ACA box 48 /// small nucleolar RNA, H/ACA box 67 /// small nucleolar RNA, C/D box 10 EIF4A1 /// LOC101928634 /// SENP3-EIF4A1 /// SNORA48 /// SNORA67 /// SNORD10 1973 /// 26781 /// 652965 /// 652966 /// 100533955 /// 101928634 NM_001204510 /// NM_001416 /// NR_002604 /// NR_002912 /// NR_002918 /// NR_037926 /// XR_244579 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201531_at NM_003407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003407.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp-36 in mouse (ZFP36), mRNA. /FEA=mRNA /GEN=ZFP36 /PROD=zinc finger protein homologous to Zfp-36 inmouse /DB_XREF=gi:4507960 /UG=Hs.1665 zinc finger protein homologous to Zfp-36 in mouse /FL=gb:M92843.1 gb:M63625.1 gb:NM_003407.1 NM_003407 ZFP36 ring finger protein ZFP36 7538 NM_003407 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from direct assay /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0017091 // AU-rich element binding // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019957 // C-C chemokine binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201532_at NM_002788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002788.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), mRNA. /FEA=mRNA /GEN=PSMA3 /PROD=proteasome (prosome, macropain) subunit, alphatype, 3 /DB_XREF=gi:4506182 /UG=Hs.167106 proteasome (prosome, macropain) subunit, alpha type, 3 /FL=gb:BC005265.1 gb:NM_002788.1 NM_002788 proteasome (prosome, macropain) subunit, alpha type, 3 PSMA3 5684 NM_002788 /// NM_152132 /// NR_038123 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from direct assay /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201533_at NM_001904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001904.1 /DEF=Homo sapiens catenin (cadherin-associated protein), beta 1 (88kD) (CTNNB1), mRNA. /FEA=mRNA /GEN=CTNNB1 /PROD=catenin (cadherin-associated protein), beta 1(88kD) /DB_XREF=gi:4503130 /UG=Hs.171271 catenin (cadherin-associated protein), beta 1 (88kD) /FL=gb:NM_001904.1 NM_001904 catenin (cadherin-associated protein), beta 1, 88kDa CTNNB1 1499 NM_001098209 /// NM_001098210 /// NM_001904 /// XM_005264886 /// XM_006712983 /// XM_006712984 /// XM_006712985 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000578 // embryonic axis specification // not recorded /// 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001569 // patterning of blood vessels // inferred by curator /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // not recorded /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001711 // endodermal cell fate commitment // not recorded /// 0001764 // neuron migration // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001840 // neural plate development // inferred from electronic annotation /// 0001889 // liver development // not recorded /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // not recorded /// 0003338 // metanephros morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // not recorded /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007398 // ectoderm development // not recorded /// 0007403 // glial cell fate determination // not recorded /// 0007494 // midgut development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009725 // response to hormone // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // not recorded /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // not recorded /// 0009987 // cellular process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from genetic interaction /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0022009 // central nervous system vasculogenesis // not recorded /// 0022405 // hair cycle process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030539 // male genitalia development // not recorded /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // not recorded /// 0030997 // regulation of centriole-centriole cohesion // inferred from direct assay /// 0031016 // pancreas development // not recorded /// 0031069 // hair follicle morphogenesis // not recorded /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // not recorded /// 0032355 // response to estradiol // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033077 // T cell differentiation in thymus // not recorded /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035112 // genitalia morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035315 // hair cell differentiation // traceable author statement /// 0036023 // embryonic skeletal limb joint morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042129 // regulation of T cell proliferation // not recorded /// 0042475 // odontogenesis of dentin-containing tooth // not recorded /// 0042493 // response to drug // inferred from expression pattern /// 0042692 // muscle cell differentiation // traceable author statement /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // not recorded /// 0043410 // positive regulation of MAPK cascade // not recorded /// 0043587 // tongue morphogenesis // not recorded /// 0043588 // skin development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // not recorded /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // not recorded /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048145 // regulation of fibroblast proliferation // traceable author statement /// 0048262 // determination of dorsal/ventral asymmetry // not recorded /// 0048469 // cell maturation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // not recorded /// 0048513 // organ development // inferred from electronic annotation /// 0048538 // thymus development // not recorded /// 0048599 // oocyte development // not recorded /// 0048617 // embryonic foregut morphogenesis // not recorded /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050808 // synapse organization // not recorded /// 0051145 // smooth muscle cell differentiation // not recorded /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0060066 // oviduct development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060173 // limb development // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060440 // trachea formation // not recorded /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060479 // lung cell differentiation // not recorded /// 0060484 // lung-associated mesenchyme development // not recorded /// 0060492 // lung induction // not recorded /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0060769 // positive regulation of epithelial cell proliferation involved in prostate gland development // not recorded /// 0060789 // hair follicle placode formation // not recorded /// 0060916 // mesenchymal cell proliferation involved in lung development // not recorded /// 0061047 // positive regulation of branching involved in lung morphogenesis // not recorded /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype /// 0061198 // fungiform papilla formation // inferred from electronic annotation /// 0061324 // canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation // inferred from sequence or structural similarity /// 0070602 // regulation of centromeric sister chromatid cohesion // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072001 // renal system development // inferred from electronic annotation /// 0072033 // renal vesicle formation // not recorded /// 0072053 // renal inner medulla development // not recorded /// 0072054 // renal outer medulla development // not recorded /// 0072079 // nephron tubule formation // not recorded /// 0072182 // regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 2000008 // regulation of protein localization to cell surface // inferred from direct assay /// 2000017 // positive regulation of determination of dorsal identity // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005916 // fascia adherens // not recorded /// 0005924 // cell-substrate adherens junction // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030027 // lamellipodium // not recorded /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030057 // desmosome // not recorded /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // not recorded /// 0032993 // protein-DNA complex // inferred from direct assay /// 0034750 // Scrib-APC-beta-catenin complex // inferred from electronic annotation /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay /// 0071664 // catenin-TCF7L2 complex // inferred from electronic annotation /// 0071944 // cell periphery // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // non-traceable author statement /// 0005198 // structural molecule activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 201534_s_at AF044221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF044221.1 /DEF=Homo sapiens HCG-1 protein (HCG-1) mRNA, complete cds. /FEA=mRNA /GEN=HCG-1 /PROD=HCG-1 protein /DB_XREF=gi:4105251 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1 AF044221 ubiquitin-like 3 UBL3 5412 NM_007106 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201535_at NM_007106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007106.1 /DEF=Homo sapiens ubiquitin-like 3 (UBL3), mRNA. /FEA=mRNA /GEN=UBL3 /PROD=ubiquitin-like 3 /DB_XREF=gi:6005927 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1 NM_007106 ubiquitin-like 3 UBL3 5412 NM_007106 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201536_at AL048503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL048503 /FEA=EST /DB_XREF=gi:5936534 /DB_XREF=est:DKFZp586M1524_s1 /CLONE=DKFZp586M1524 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 AL048503 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201537_s_at BC002682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002682.1 /DEF=Homo sapiens, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related), clone MGC:3615, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 3 (vaccinia virusphosphatase VH1-related) /DB_XREF=gi:12803692 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 BC002682 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201538_s_at NM_004090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004090.1 /DEF=Homo sapiens dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (DUSP3), mRNA. /FEA=mRNA /GEN=DUSP3 /PROD=dual specificity phosphatase 3 /DB_XREF=gi:4758207 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 NM_004090 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201539_s_at U29538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U29538.1 /DEF=Human heart protein with four and a half LIM domains (FHL-1) mRNA, complete cds. /FEA=mRNA /GEN=FHL-1 /DB_XREF=gi:2078479 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1 U29538 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201540_at NM_001449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001449.1 /DEF=Homo sapiens four and a half LIM domains 1 (FHL1), mRNA. /FEA=mRNA /GEN=FHL1 /PROD=four and a half LIM domains 1 /DB_XREF=gi:4503720 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1 NM_001449 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201541_s_at NM_006349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006349.1 /DEF=Homo sapiens putative cyclin G1 interacting protein (CG1I), mRNA. /FEA=mRNA /GEN=CG1I /PROD=putative cyclin G1 interacting protein /DB_XREF=gi:5453616 /UG=Hs.10028 putative cyclin G1 interacting protein /FL=gb:U61837.1 gb:NM_006349.1 NM_006349 zinc finger, HIT-type containing 1 ZNHIT1 10467 NM_006349 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0042129 // regulation of T cell proliferation // inferred from electronic annotation /// 0070317 // negative regulation of G0 to G1 transition // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201542_at AY008268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY008268.1 /DEF=Homo sapiens GTP-binding protein SAR1 (SAR1) mRNA, complete cds. /FEA=mRNA /GEN=SAR1 /PROD=GTP-binding protein SAR1 /DB_XREF=gi:10445220 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1 AY008268 secretion associated, Ras related GTPase 1A SAR1A 56681 NM_001142648 /// NM_020150 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201543_s_at NM_020150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020150.1 /DEF=Homo sapiens SAR1 protein (SAR1), mRNA. /FEA=mRNA /GEN=SAR1 /PROD=SAR1 protein /DB_XREF=gi:9910541 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1 NM_020150 secretion associated, Ras related GTPase 1A SAR1A 56681 NM_001142648 /// NM_020150 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201544_x_at BF675004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF675004 /FEA=EST /DB_XREF=gi:11948899 /DB_XREF=est:602138088F1 /CLONE=IMAGE:4274564 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1 BF675004 BCL2-like 2 /// BCL2L2-PABPN1 readthrough /// poly(A) binding protein, nuclear 1 BCL2L2 /// BCL2L2-PABPN1 /// PABPN1 599 /// 8106 /// 100529063 NM_001199839 /// NM_001199864 /// NM_004050 /// NM_004643 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0010467 // gene expression // traceable author statement /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0046778 // modification by virus of host mRNA processing // traceable author statement /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // not recorded /// 0051400 // BH domain binding // inferred from electronic annotation 201545_s_at NM_004643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004643.1 /DEF=Homo sapiens poly(A)-binding protein, nuclear 1 (PABPN1), mRNA. /FEA=mRNA /GEN=PABPN1 /PROD=poly(A)-binding protein, nuclear 1 /DB_XREF=gi:4758875 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1 NM_004643 BCL2L2-PABPN1 readthrough /// poly(A) binding protein, nuclear 1 BCL2L2-PABPN1 /// PABPN1 8106 /// 100529063 NM_001199864 /// NM_004643 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0046778 // modification by virus of host mRNA processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201546_at NM_004238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004238.1 /DEF=Homo sapiens thyroid hormone receptor interactor 12 (TRIP12), mRNA. /FEA=mRNA /GEN=TRIP12 /PROD=thyroid hormone receptor interactor 12 /DB_XREF=gi:10863902 /UG=Hs.138617 thyroid hormone receptor interactor 12 /FL=gb:NM_004238.1 gb:D28476.1 NM_004238 thyroid hormone receptor interactor 12 TRIP12 9320 NM_001284214 /// NM_001284215 /// NM_001284216 /// NM_004238 /// XM_005246954 /// XM_005246955 /// XM_005246956 /// XM_005246957 /// XM_005246958 /// XM_005246960 /// XM_005246961 /// XM_005246962 /// XM_005246963 /// XM_006712852 /// XM_006712853 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201547_at AA729218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA729218 /FEA=EST /DB_XREF=gi:2750577 /DB_XREF=est:nx35a04.s1 /CLONE=IMAGE:1258062 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 AA729218 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 201548_s_at W02593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W02593 /FEA=EST /DB_XREF=gi:1274571 /DB_XREF=est:za51e06.r1 /CLONE=IMAGE:296098 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 W02593 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 201549_x_at NM_006618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006618.1 /DEF=Homo sapiens putative DNAchromatin binding motif (PLU-1), mRNA. /FEA=mRNA /GEN=PLU-1 /PROD=putative DNAchromatin binding motif /DB_XREF=gi:5729977 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 NM_006618 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 201550_x_at NM_001614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001614.2 /DEF=Homo sapiens actin, gamma 1 (ACTG1), mRNA. /FEA=mRNA /GEN=ACTG1 /PROD=actin, gamma 1 propeptide /DB_XREF=gi:11038618 /UG=Hs.14376 actin, gamma 1 /FL=gb:NM_001614.2 gb:BC000292.1 NM_001614 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 201551_s_at J03263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03263.1 /DEF=Human lysosome-associated membrane glycoprotein (lamp A) mRNA, complete cds. /FEA=mRNA /GEN=LAMP1 /DB_XREF=gi:187178 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 J03263 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201552_at NM_005561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201553_s_at NM_005561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201554_x_at NM_004130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004130.1 /DEF=Homo sapiens glycogenin (GYG), mRNA. /FEA=mRNA /GEN=GYG /PROD=glycogenin /DB_XREF=gi:4758491 /UG=Hs.174071 glycogenin /FL=gb:U44131.1 gb:BC000033.1 gb:NM_004130.1 gb:U31525.1 NM_004130 glycogenin 1 GYG1 2992 NM_001184720 /// NM_001184721 /// NM_004130 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201555_at NM_002388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002388.2 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 3 (MCM3), mRNA. /FEA=mRNA /GEN=MCM3 /PROD=minichromosome maintenance deficient (S.cerevisiae) 3 /DB_XREF=gi:6631094 /UG=Hs.179565 minichromosome maintenance deficient (S. cerevisiae) 3 /FL=gb:BC001626.1 gb:NM_002388.2 gb:D38073.1 NM_002388 minichromosome maintenance complex component 3 MCM3 4172 NM_001270472 /// NM_002388 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005658 // alpha DNA polymerase:primase complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201556_s_at BC002737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002737.1 /DEF=Homo sapiens, vesicle-associated membrane protein 2, clone MGC:3377, mRNA, complete cds. /FEA=mRNA /PROD=vesicle-associated membrane protein 2 /DB_XREF=gi:12803794 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1 BC002737 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 /// XM_005256775 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030667 // secretory granule membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 201557_at NM_014232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014232.1 /DEF=Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2), mRNA. /FEA=mRNA /GEN=VAMP2 /PROD=vesicle-associated membrane protein 2(synaptobrevin 2) /DB_XREF=gi:7657674 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1 NM_014232 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 /// XM_005256775 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030667 // secretory granule membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 201558_at NM_003610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003610.1 /DEF=Homo sapiens RAE1 (RNA export 1, S.pombe) homolog (RAE1), mRNA. /FEA=mRNA /GEN=RAE1 /PROD=RAE1 (RNA export 1, S.pombe) homolog /DB_XREF=gi:4506398 /UG=Hs.196209 RAE1 (RNA export 1, S.pombe) homolog /FL=gb:U84720.1 gb:NM_003610.1 NM_003610 ribonucleic acid export 1 RAE1 8480 NM_001015885 /// NM_003610 /// XM_005260582 /// XM_005260583 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005640 // nuclear outer membrane // traceable author statement /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 201559_s_at AF109196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109196.1 /DEF=Homo sapiens intracellular chloride channel p64H1 mRNA, complete cds. /FEA=mRNA /PROD=intracellular chloride channel p64H1 /DB_XREF=gi:4588523 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1 AF109196 chloride intracellular channel 4 CLIC4 25932 NM_013943 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // non-traceable author statement /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201560_at NM_013943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013943.1 /DEF=Homo sapiens chloride intracellular channel 4 (CLIC4), mRNA. /FEA=mRNA /GEN=CLIC4 /PROD=chloride intracellular channel 4 /DB_XREF=gi:7330334 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1 NM_013943 chloride intracellular channel 4 CLIC4 25932 NM_013943 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // non-traceable author statement /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201561_s_at NM_014944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014944.1 /DEF=Homo sapiens KIAA0911 protein (KIAA0911), mRNA. /FEA=mRNA /GEN=KIAA0911 /PROD=KIAA0911 protein /DB_XREF=gi:7662373 /UG=Hs.29665 KIAA0911 protein /FL=gb:AB020718.1 gb:NM_014944.1 NM_014944 calsyntenin 1 CLSTN1 22883 NM_001009566 /// NM_014944 /// XM_005263432 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0042988 // X11-like protein binding // inferred from physical interaction 201562_s_at NM_003104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003104.1 /DEF=Homo sapiens sorbitol dehydrogenase (SORD), mRNA. /FEA=mRNA /GEN=SORD /PROD=sorbitol dehydrogenase /DB_XREF=gi:4507154 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1 NM_003104 sorbitol dehydrogenase SORD 6652 NM_003104 /// NR_034039 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay 201563_at L29008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L29008.1 /DEF=Human L-iditol-2 dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=L-iditol-2 dehydrogenase /DB_XREF=gi:496077 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1 L29008 sorbitol dehydrogenase SORD 6652 NM_003104 /// NR_034039 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay 201564_s_at NM_003088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003088.1 /DEF=Homo sapiens singed (Drosophila)-like (sea urchin fascin homolog like) (SNL), mRNA. /FEA=mRNA /GEN=SNL /PROD=singed (Drosophila)-like (sea urchin fascinhomolog like) /DB_XREF=gi:4507114 /UG=Hs.118400 singed (Drosophila)-like (sea urchin fascin homolog like) /FL=gb:BC000521.1 gb:NM_003088.1 gb:U03057.1 gb:U09873.1 NM_003088 fascin actin-bundling protein 1 FSCN1 6624 NM_003088 0008283 // cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0048870 // cell motility // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071437 // invadopodium // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 201565_s_at NM_002166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002166.1 /DEF=Homo sapiens inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2), mRNA. /FEA=mRNA /GEN=ID2 /PROD=inhibitor of DNA binding 2, dominant negativehelix-loop-helix protein /DB_XREF=gi:4504570 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1 NM_002166 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein ID2 3398 NM_002166 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred by curator /// 0090398 // cellular senescence // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 201566_x_at D13891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13891.1 /DEF=Human mRNA for Id-2H, complete cds. /FEA=mRNA /GEN=Id-2H /PROD=Id-2H /DB_XREF=gi:464183 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1 D13891 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein ID2 3398 NM_002166 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred by curator /// 0090398 // cellular senescence // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 201567_s_at NM_002078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002078.2 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA. /FEA=mRNA /GEN=GOLGA4 /PROD=golgi autoantigen, golgin subfamily a, 4 /DB_XREF=gi:6715599 /UG=Hs.183773 golgi autoantigen, golgin subfamily a, 4 /FL=gb:U41740.1 gb:NM_002078.2 NM_002078 golgin A4 GOLGA4 2803 NM_001172713 /// NM_002078 /// XM_005265069 /// XM_005265070 /// XM_005265071 /// XM_005265072 /// XM_005265073 /// XM_005265074 /// XM_005265075 /// XM_006713110 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from physical interaction 201568_at NM_014402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014402.1 /DEF=Homo sapiens low molecular mass ubiquinone-binding protein (9.5kD) (QP-C), mRNA. /FEA=mRNA /GEN=QP-C /PROD=low molecular mass ubiquinone-binding protein /DB_XREF=gi:7657485 /UG=Hs.3709 low molecular mass ubiquinone-binding protein (9.5kD) /FL=gb:BC001390.1 gb:D50369.1 gb:NM_014402.1 NM_014402 ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa UQCRQ 27089 NM_014402 0021539 // subthalamus development // inferred from electronic annotation /// 0021548 // pons development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation 201569_s_at NM_015380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1 NM_015380 SAMM50 sorting and assembly machinery component SAMM50 25813 NM_015380 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019867 // outer membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201570_at NM_015380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1 NM_015380 SAMM50 sorting and assembly machinery component SAMM50 25813 NM_015380 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019867 // outer membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201571_s_at AI656493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI656493 /FEA=EST /DB_XREF=gi:4740472 /DB_XREF=est:tt51d09.x1 /CLONE=IMAGE:2244305 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1 AI656493 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 /// XM_005262778 /// XM_005262779 /// XM_005262780 /// XM_005262781 /// XM_005262782 /// XM_006714113 /// XM_006714114 /// XM_006714115 /// XM_006714116 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201572_x_at NM_001921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001921.1 /DEF=Homo sapiens dCMP deaminase (DCTD), mRNA. /FEA=mRNA /GEN=DCTD /PROD=dCMP deaminase /DB_XREF=gi:4503276 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1 NM_001921 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 /// XM_005262778 /// XM_005262779 /// XM_005262780 /// XM_005262781 /// XM_005262782 /// XM_006714113 /// XM_006714114 /// XM_006714115 /// XM_006714116 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201573_s_at M75715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M75715.1 /DEF=Human TB3-1 mRNA, complete cds. /FEA=mRNA /PROD=TB3-1 /DB_XREF=gi:338686 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1 M75715 eukaryotic translation termination factor 1 ETF1 2107 NM_001256302 /// NM_001282185 /// NM_001291974 /// NM_001291975 /// NM_004730 /// XM_005271920 /// XM_005271921 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006449 // regulation of translational termination // traceable author statement /// 0006479 // protein methylation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201574_at NM_004730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004730.1 /DEF=Homo sapiens eukaryotic translation termination factor 1 (ETF1), mRNA. /FEA=mRNA /GEN=ETF1 /PROD=eukaryotic translation termination factor 1 /DB_XREF=gi:4759033 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1 NM_004730 eukaryotic translation termination factor 1 ETF1 2107 NM_001256302 /// NM_001282185 /// NM_001291974 /// NM_001291975 /// NM_004730 /// XM_005271920 /// XM_005271921 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006449 // regulation of translational termination // traceable author statement /// 0006479 // protein methylation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201575_at NM_012245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012245.1 /DEF=Homo sapiens SKI-INTERACTING PROTEIN (SNW1), mRNA. /FEA=mRNA /GEN=SNW1 /PROD=SKI-INTERACTING PROTEIN /DB_XREF=gi:6912675 /UG=Hs.79008 SKI-INTERACTING PROTEIN /FL=gb:U51432.1 gb:AF045184.1 gb:NM_012245.1 NM_012245 SNW domain containing 1 SNW1 22938 NM_012245 /// XM_005267413 /// XM_005267414 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048385 // regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0070564 // positive regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071146 // SMAD3-SMAD4 protein complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay 201576_s_at NM_000404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000404.1 /DEF=Homo sapiens galactosidase, beta 1 (GLB1), mRNA. /FEA=mRNA /GEN=GLB1 /PROD=galactosidase, beta 1 /DB_XREF=gi:10834965 /UG=Hs.79222 galactosidase, beta 1 /FL=gb:NM_000404.1 gb:M27507.1 gb:M22590.1 gb:M34423.1 NM_000404 galactosidase, beta 1 /// transmembrane protein with metallophosphoesterase domain GLB1 /// TMPPE 2720 /// 643853 NM_000404 /// NM_001039770 /// NM_001079811 /// NM_001135602 /// NM_001136238 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019388 // galactose catabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0009341 // beta-galactosidase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016936 // galactoside binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201577_at NM_000269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000269.1 /DEF=Homo sapiens non-metastatic cells 1, protein (NM23A) expressed in (NME1), mRNA. /FEA=mRNA /GEN=NME1 /PROD=non-metastatic cells 1 protein /DB_XREF=gi:4557796 /UG=Hs.118638 non-metastatic cells 1, protein (NM23A) expressed in /FL=gb:BC000293.1 gb:NM_000269.1 NM_000269 NME/NM23 nucleoside diphosphate kinase 1 NME1 4830 NM_000269 /// NM_198175 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006308 // DNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018106 // peptidyl-histidine phosphorylation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004673 // protein histidine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0043024 // ribosomal small subunit binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201578_at NM_005397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005397.1 /DEF=Homo sapiens podocalyxin-like (PODXL), mRNA. /FEA=mRNA /GEN=PODXL /PROD=podocalyxin-like /DB_XREF=gi:4885556 /UG=Hs.16426 podocalyxin-like /FL=gb:U97519.1 gb:NM_005397.1 NM_005397 podocalyxin-like PODXL 5420 NM_001018111 /// NM_005397 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0022408 // negative regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032534 // regulation of microvillus assembly // inferred from sequence or structural similarity /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 0072175 // epithelial tube formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031528 // microvillus membrane // inferred from sequence or structural similarity /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201579_at NM_005245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005245.1 /DEF=Homo sapiens FAT tumor suppressor (Drosophila) homolog (FAT), mRNA. /FEA=mRNA /GEN=FAT /PROD=FAT tumor suppressor precursor /DB_XREF=gi:4885228 /UG=Hs.166994 FAT tumor suppressor (Drosophila) homolog /FL=gb:NM_005245.1 NM_005245 FAT atypical cadherin 1 FAT1 2195 NM_005245 /// XM_005262834 /// XM_005262835 /// XM_006714139 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201580_s_at AL544094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL544094 /FEA=EST /DB_XREF=gi:12876573 /DB_XREF=est:AL544094 /CLONE=CS0DI004YG20 (3 prime) /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 AL544094 thioredoxin-related transmembrane protein 4 TMX4 56255 NM_021156 0006457 // protein folding // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded 201581_at BF572868 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF572868 /FEA=EST /DB_XREF=gi:11646580 /DB_XREF=est:602079440F2 /CLONE=IMAGE:4254176 /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 BF572868 thioredoxin-related transmembrane protein 4 TMX4 56255 NM_021156 0006457 // protein folding // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded 201582_at AL121900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121900 /DEF=Human DNA sequence from clone RP11-379J5 on chromosome 20 Contains the last exon of the SEC23B gene for Sec23 (S. cerevisiae) homolog B, a putative novel gene, the 5 end of the gene for a novel protein similar to bacterial histidyl-tRNA synthetas... /FEA=mRNA /DB_XREF=gi:11121203 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1 AL121900 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_001172745 /// NM_001172746 /// NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 201583_s_at NM_006363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006363.1 /DEF=Homo sapiens Sec23 (S. cerevisiae) homolog B (SEC23B), mRNA. /FEA=mRNA /GEN=SEC23B /PROD=Sec23 (S. cerevisiae) homolog B /DB_XREF=gi:5454043 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1 NM_006363 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_001172745 /// NM_001172746 /// NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 201584_s_at NM_005804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005804.1 /DEF=Homo sapiens nuclear RNA helicase, DECD variant of DEAD box family (DDXL), mRNA. /FEA=mRNA /GEN=DDXL /PROD=nuclear RNA helicase, DECD variant of DEAD boxfamily /DB_XREF=gi:5031658 /UG=Hs.179606 nuclear RNA helicase, DECD variant of DEAD box family /FL=gb:BC001009.1 gb:U90426.1 gb:NM_005804.1 NM_005804 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A DDX39A 10212 NM_001204057 /// NM_005804 /// NM_138998 /// NR_038336 /// NR_046366 /// XM_006722606 0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201585_s_at BG035151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG035151 /FEA=EST /DB_XREF=gi:12428997 /DB_XREF=est:602324851F1 /CLONE=IMAGE:4412917 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1 BG035151 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201586_s_at NM_005066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005066.1 /DEF=Homo sapiens splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) (SFPQ), mRNA. /FEA=mRNA /GEN=SFPQ /PROD=splicing factor prolineglutamine rich(polypyrimidine tract-binding protein-associated) /DB_XREF=gi:4826997 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1 NM_005066 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201587_s_at NM_001569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001569.2 /DEF=Homo sapiens interleukin-1 receptor-associated kinase 1 (IRAK1), mRNA. /FEA=mRNA /GEN=IRAK1 /PROD=interleukin-1 receptor-associated kinase 1 /DB_XREF=gi:4755143 /UG=Hs.182018 interleukin-1 receptor-associated kinase 1 /FL=gb:L76191.1 gb:NM_001569.2 NM_001569 interleukin-1 receptor-associated kinase 1 IRAK1 3654 NM_001025242 /// NM_001025243 /// NM_001569 /// XM_005274668 0000187 // activation of MAPK activity // traceable author statement /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0045323 // interleukin-1 receptor complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201588_at NM_004786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004786.1 /DEF=Homo sapiens thioredoxin-like, 32kD (TXNL), mRNA. /FEA=mRNA /GEN=TXNL /PROD=thioredoxin-like, 32kD /DB_XREF=gi:4759273 /UG=Hs.18792 thioredoxin-like, 32kD /FL=gb:BC001156.1 gb:AF003938.1 gb:AF051896.1 gb:AF052659.1 gb:NM_004786.1 NM_004786 thioredoxin-like 1 TXNL1 9352 NM_004786 /// NR_024546 /// XM_006722580 /// XM_006722581 /// XR_430086 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015036 // disulfide oxidoreductase activity // inferred from direct assay 201589_at D80000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D80000.1 /DEF=Human mRNA for KIAA0178 gene, partial cds. /FEA=mRNA /GEN=KIAA0178 /DB_XREF=gi:1136415 /UG=Hs.211602 SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 /FL=gb:NM_006306.1 D80000 structural maintenance of chromosomes 1A SMC1A 8243 NM_001281463 /// NM_006306 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007064 // mitotic sister chromatid cohesion // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0009314 // response to radiation // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from electronic annotation /// 0008280 // cohesin core heterodimer // traceable author statement /// 0030893 // meiotic cohesin complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201590_x_at NM_004039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004039.1 /DEF=Homo sapiens annexin A2 (ANXA2), mRNA. /FEA=mRNA /GEN=ANXA2 /PROD=annexin A2 /DB_XREF=gi:4757755 /UG=Hs.217493 annexin A2 /FL=gb:BC001748.1 gb:D00017.1 gb:NM_004039.1 NM_004039 annexin A2 ANXA2 302 NM_001002857 /// NM_001002858 /// NM_001136015 /// NM_004039 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201591_s_at NM_007184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007184.1 /DEF=Homo sapiens imidazoline receptor candidate (I-1), mRNA. /FEA=mRNA /GEN=I-1 /PROD=imidazoline receptor candidate /DB_XREF=gi:6005787 /UG=Hs.26285 imidazoline receptor candidate /FL=gb:AF082516.1 gb:NM_007184.1 NM_007184 nischarin NISCH 11188 NM_001276293 /// NM_001276294 /// NM_007184 /// XM_005264839 /// XM_006712955 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0048243 // norepinephrine secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008227 // G-protein coupled amine receptor activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201592_at NM_003756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003756.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) (EIF3S3), mRNA. /FEA=mRNA /GEN=EIF3S3 /PROD=eukaryotic translation initiation factor 3,subunit 3 (gamma, 40kD) /DB_XREF=gi:4503514 /UG=Hs.58189 eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) /FL=gb:BC000386.1 gb:U54559.1 gb:NM_003756.1 NM_003756 eukaryotic translation initiation factor 3, subunit H EIF3H 8667 NM_003756 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201593_s_at AV716798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV716798 /FEA=EST /DB_XREF=gi:10813950 /DB_XREF=est:AV716798 /CLONE=DCBAKB02 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1 AV716798 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201594_s_at NM_005134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005134.1 /DEF=Homo sapiens protein phosphatase 4, regulatory subunit 1 (PPP4R1), mRNA. /FEA=mRNA /GEN=PPP4R1 /PROD=protein phosphatase 4, regulatory subunit 1 /DB_XREF=gi:4826933 /UG=Hs.3382 protein phosphatase 4, regulatory subunit 1 /FL=gb:AF111106.1 gb:NM_005134.1 gb:AF100744.1 NM_005134 protein phosphatase 4, regulatory subunit 1 PPP4R1 9989 NM_001042388 /// NM_005134 /// NR_052003 /// XR_430048 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // non-traceable author statement 0030289 // protein phosphatase 4 complex // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030362 // protein phosphatase type 4 regulator activity // non-traceable author statement 201595_s_at NM_018471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018471.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT010 (HT010), mRNA. /FEA=mRNA /GEN=HT010 /PROD=uncharacterized hypothalamus protein HT010 /DB_XREF=gi:8923807 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1 NM_018471 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201596_x_at NM_000224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000224.1 /DEF=Homo sapiens keratin 18 (KRT18), mRNA. /FEA=mRNA /GEN=KRT18 /PROD=keratin 18 /DB_XREF=gi:4557887 /UG=Hs.65114 keratin 18 /FL=gb:BC000698.1 gb:BC000180.2 gb:BC004253.1 gb:M26326.1 gb:NM_000224.1 NM_000224 keratin 18 KRT18 3875 NM_000224 /// NM_199187 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0043000 // Golgi to plasma membrane CFTR protein transport // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 201597_at NM_001865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001865.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (COX7A2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX7A2 /PROD=cytochrome c oxidase subunit VIIa polypeptide 2(liver) /DB_XREF=gi:4502988 /UG=Hs.70312 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) /FL=gb:NM_001865.1 NM_001865 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) COX7A2 1347 NM_001865 /// NR_029466 /// XM_006715335 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201598_s_at NM_001567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001567.2 /DEF=Homo sapiens inositol polyphosphate phosphatase-like 1 (INPPL1), mRNA. /FEA=mRNA /GEN=INPPL1 /PROD=inositol polyphosphate phosphatase-like 1 /DB_XREF=gi:4755141 /UG=Hs.75339 inositol polyphosphate phosphatase-like 1 /FL=gb:NM_001567.2 gb:L24444.1 NM_001567 inositol polyphosphate phosphatase-like 1 INPPL1 3636 NM_001567 /// XM_005273978 /// XM_005273979 /// XM_006718534 /// XM_006718535 /// XM_006718536 /// XM_006718537 0001958 // endochondral ossification // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0007155 // cell adhesion // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0097178 // ruffle assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction 201599_at NM_000274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000274.1 /DEF=Homo sapiens ornithine aminotransferase (gyrate atrophy) (OAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OAT /PROD=ornithine aminotransferase precursor /DB_XREF=gi:4557808 /UG=Hs.75485 ornithine aminotransferase (gyrate atrophy) /FL=gb:BC000964.1 gb:M12267.1 gb:M23204.1 gb:M14963.1 gb:NM_000274.1 NM_000274 ornithine aminotransferase OAT 4942 NM_000274 /// NM_001171814 /// XM_006717871 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0034214 // protein hexamerization // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004587 // ornithine-oxo-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 201600_at NM_007273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007273.1 /DEF=Homo sapiens B-cell associated protein (REA), mRNA. /FEA=mRNA /GEN=REA /PROD=B-cell associated protein /DB_XREF=gi:6005853 /UG=Hs.7771 B-cell associated protein /FL=gb:AF150962.1 gb:NM_007273.1 gb:AF126021.1 gb:AF178980.1 NM_007273 prohibitin 2 PHB2 11331 NM_001144831 /// NM_001267700 /// XR_242980 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // non-traceable author statement 201601_x_at NM_003641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003641.1 /DEF=Homo sapiens interferon induced transmembrane protein 1 (9-27) (IFITM1), mRNA. /FEA=mRNA /GEN=IFITM1 /PROD=interferon induced transmembrane protein 1(9-27) /DB_XREF=gi:4504580 /UG=Hs.146360 interferon induced transmembrane protein 1 (9-27) /FL=gb:BC000897.1 gb:J04164.1 gb:NM_003641.1 NM_003641 interferon induced transmembrane protein 1 /// interferon induced transmembrane protein 2 IFITM1 /// IFITM2 8519 /// 10581 NM_003641 /// NM_006435 0001503 // ossification // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201602_s_at BE737620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE737620 /FEA=EST /DB_XREF=gi:10151612 /DB_XREF=est:601572895F1 /CLONE=IMAGE:3839831 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 BE737620 protein phosphatase 1, regulatory subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201603_at AI817061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817061 /FEA=EST /DB_XREF=gi:5436140 /DB_XREF=est:wj76e05.x1 /CLONE=IMAGE:2408768 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 AI817061 protein phosphatase 1, regulatory subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201604_s_at NM_002480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002480.1 /DEF=Homo sapiens myosin phosphatase, target subunit 1 (MYPT1), mRNA. /FEA=mRNA /GEN=MYPT1 /PROD=myosin phosphatase target subunit 1 /DB_XREF=gi:4505316 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 NM_002480 protein phosphatase 1, regulatory subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201605_x_at NM_004368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004368.1 /DEF=Homo sapiens calponin 2 (CNN2), mRNA. /FEA=mRNA /GEN=CNN2 /PROD=calponin 2 /DB_XREF=gi:4758017 /UG=Hs.169718 calponin 2 /FL=gb:D83735.1 gb:NM_004368.1 NM_004368 calponin 2 CNN2 1265 NM_004368 /// NM_201277 0007010 // cytoskeleton organization // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0032970 // regulation of actin filament-based process // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 201606_s_at BE796924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE796924 /FEA=EST /DB_XREF=gi:10218031 /DB_XREF=est:601587284F1 /CLONE=IMAGE:3941445 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 BE796924 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201607_at AI694451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694451 /FEA=EST /DB_XREF=gi:4971791 /DB_XREF=est:wd83h06.x1 /CLONE=IMAGE:2338235 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 AI694451 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201608_s_at NM_007062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007062.1 /DEF=Homo sapiens nuclear phosphoprotein similar to S. cerevisiae PWP1 (PWP1), mRNA. /FEA=mRNA /GEN=PWP1 /PROD=nuclear phosphoprotein similar to S. cerevisiaePWP1 /DB_XREF=gi:5902033 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 NM_007062 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201609_x_at AL578502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL578502 /FEA=EST /DB_XREF=gi:12942638 /DB_XREF=est:AL578502 /CLONE=CS0DK011YK08 (3 prime) /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 AL578502 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201610_at AF064084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF064084.1 /DEF=Homo sapiens prenylcysteine carboxyl methyltransferase (PCCMT) mRNA, complete cds. /FEA=mRNA /GEN=PCCMT /PROD=prenylcysteine carboxyl methyltransferase /DB_XREF=gi:3135668 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 AF064084 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201611_s_at NM_012405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012405.1 /DEF=Homo sapiens isoprenylcysteine carboxyl methyltransferase (ICMT), mRNA. /FEA=mRNA /GEN=ICMT /PROD=isoprenylcysteine carboxyl methyltransferase /DB_XREF=gi:6912429 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 NM_012405 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201612_at NM_000696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000696.1 /DEF=Homo sapiens aldehyde dehydrogenase 9 (gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) (ALDH9), mRNA. /FEA=mRNA /GEN=ALDH9 /PROD=aldehyde dehydrogenase 9(gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) /DB_XREF=gi:4502046 /UG=Hs.2533 aldehyde dehydrogenase 9 family, member A1 /FL=gb:U34252.1 gb:NM_000696.1 gb:AF172093.1 NM_000696 aldehyde dehydrogenase 9 family, member A1 ALDH9A1 223 NM_000696 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // inferred from direct assay /// 0042445 // hormone metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from electronic annotation /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019145 // aminobutyraldehyde dehydrogenase activity // inferred from direct assay /// 0033737 // 1-pyrroline dehydrogenase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043176 // amine binding // inferred from electronic annotation /// 0047105 // 4-trimethylammoniobutyraldehyde dehydrogenase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201613_s_at BC000519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000519.1 /DEF=Homo sapiens, RuvB (E coli homolog)-like 1, clone MGC:8557, mRNA, complete cds. /FEA=mRNA /PROD=RuvB (E coli homolog)-like 1 /DB_XREF=gi:12653494 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1 BC000519 adaptor-related protein complex 1, gamma 2 subunit AP1G2 8906 NM_001282474 /// NM_001282475 /// NM_003917 /// NM_080545 /// XM_005268166 /// XM_005268167 /// XM_005268168 /// XM_005268169 /// XM_005268170 /// XM_005268171 /// XM_005268172 /// XM_005268173 /// XM_005268174 /// XM_005268175 /// XM_005268176 /// XM_005268177 /// XM_005268178 /// XM_005268179 /// XM_005268180 /// XM_005268181 /// XM_005268182 /// XM_006720301 /// XR_245729 /// XR_245730 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 201614_s_at NM_003707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003707.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 1 (RUVBL1), mRNA. /FEA=mRNA /GEN=RUVBL1 /PROD=TATA binding protein interacting protein 49 kDa /DB_XREF=gi:4506752 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1 NM_003707 RuvB-like AAA ATPase 1 RUVBL1 8607 NM_003707 /// XM_005247841 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from electronic annotation 201615_x_at AI685060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI685060 /FEA=EST /DB_XREF=gi:4896365 /DB_XREF=est:wc67a07.x1 /CLONE=IMAGE:2323668 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AI685060 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201616_s_at AL577531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL577531 /FEA=EST /DB_XREF=gi:12940753 /DB_XREF=est:AL577531 /CLONE=CS0DI087YP20 (3 prime) /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AL577531 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201617_x_at NM_004342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004342.2 /DEF=Homo sapiens caldesmon 1 (CALD1), mRNA. /FEA=mRNA /GEN=CALD1 /PROD=caldesmon 1 /DB_XREF=gi:11091984 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 NM_004342 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201618_x_at NM_003801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003801.2 /DEF=Homo sapiens anchor attachment protein 1 (Gaa1p, yeast) homolog (GPAA1), mRNA. /FEA=mRNA /GEN=GPAA1 /PROD=anchor attachment protein 1 /DB_XREF=gi:6031166 /UG=Hs.4742 anchor attachment protein 1 (Gaa1p, yeast) homolog /FL=gb:BC003171.1 gb:BC004129.1 gb:AB006969.1 gb:AB002135.1 gb:NM_003801.2 NM_003801 glycosylphosphatidylinositol anchor attachment 1 GPAA1 8733 NM_003801 0006461 // protein complex assembly // non-traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042765 // GPI-anchor transamidase complex // traceable author statement 0003923 // GPI-anchor transamidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // non-traceable author statement /// 0034235 // GPI anchor binding // inferred from mutant phenotype 201619_at NM_006793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006793.1 /DEF=Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PRDX3 /PROD=peroxiredoxin 3 /DB_XREF=gi:5802973 /UG=Hs.75454 peroxiredoxin 3 /FL=gb:BC002685.1 gb:NM_006793.1 gb:D49396.1 NM_006793 peroxiredoxin 3 PRDX3 10935 NM_006793 /// NM_014098 0001893 // maternal placenta development // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018171 // peptidyl-cysteine oxidation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from genetic interaction /// 0042744 // hydrogen peroxide catabolic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008785 // alkyl hydroperoxide reductase activity // non-traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201620_at NM_003791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003791.1 /DEF=Homo sapiens membrane-bound transcription factor protease, site 1 (MBTPS1), mRNA. /FEA=mRNA /GEN=MBTPS1 /PROD=site-1 protease preproprotein /DB_XREF=gi:4506774 /UG=Hs.75890 membrane-bound transcription factor protease, site 1 /FL=gb:NM_003791.1 gb:D42053.1 NM_003791 membrane-bound transcription factor peptidase, site 1 MBTPS1 8720 NM_003791 /// NM_201268 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // not recorded /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // not recorded /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201621_at NM_005380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005380.1 /DEF=Homo sapiens neuroblastoma, suppression of tumorigenicity 1 (NBL1), mRNA. /FEA=mRNA /GEN=NBL1 /PROD=neuroblastoma, suppression of tumorigenicity 1 /DB_XREF=gi:4885508 /UG=Hs.76307 neuroblastoma, suppression of tumorigenicity 1 /FL=gb:NM_005380.1 gb:D28124.1 NM_005380 neuroblastoma 1, DAN family BMP antagonist NBL1 4681 NM_001204084 /// NM_001204085 /// NM_001204086 /// NM_001278164 /// NM_001278165 /// NM_001278166 /// NM_005380 /// NM_182744 0007399 // nervous system development // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0038098 // sequestering of BMP from receptor via BMP binding // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048263 // determination of dorsal identity // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005739 // mitochondrion // /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016015 // morphogen activity // inferred from sequence or structural similarity /// 0036122 // BMP binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 201622_at NM_014390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014390.1 /DEF=Homo sapiens EBNA-2 co-activator (100kD) (p100), mRNA. /FEA=mRNA /GEN=p100 /PROD=EBNA-2 co-activator (100kD) /DB_XREF=gi:7657430 /UG=Hs.79093 EBNA-2 co-activator (100kD) /FL=gb:NM_014390.1 gb:U22055.1 NM_014390 staphylococcal nuclease and tudor domain containing 1 SND1 27044 NM_014390 0001649 // osteoblast differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201623_s_at BC000629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000629.1 /DEF=Homo sapiens, Similar to aspartyl-tRNA synthetase, clone MGC:1562, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aspartyl-tRNA synthetase /DB_XREF=gi:12653688 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1 BC000629 aspartyl-tRNA synthetase DARS 1615 NM_001293312 /// NM_001349 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201624_at NM_001349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001349.1 /DEF=Homo sapiens aspartyl-tRNA synthetase (DARS), mRNA. /FEA=mRNA /GEN=DARS /PROD=aspartyl-tRNA synthetase /DB_XREF=gi:4557512 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1 NM_001349 aspartyl-tRNA synthetase DARS 1615 NM_001293312 /// NM_001349 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201625_s_at BE300521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE300521 /FEA=EST /DB_XREF=gi:9184269 /DB_XREF=est:ba69f11.x1 /CLONE=IMAGE:2905677 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BE300521 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201626_at BG292233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG292233 /FEA=EST /DB_XREF=gi:13050848 /DB_XREF=est:602386668F1 /CLONE=IMAGE:4515521 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BG292233 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201627_s_at NM_005542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005542.1 /DEF=Homo sapiens insulin induced gene 1 (INSIG1), mRNA. /FEA=mRNA /GEN=INSIG1 /PROD=insulin induced gene 1 /DB_XREF=gi:5031800 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 NM_005542 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201628_s_at NM_006570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006570.1 /DEF=Homo sapiens Ras-related GTP-binding protein (RAGA), mRNA. /FEA=mRNA /GEN=RAGA /PROD=Ras-related GTP-binding protein /DB_XREF=gi:5729998 /UG=Hs.57304 Ras-related GTP-binding protein /FL=gb:U41654.1 gb:NM_006570.1 NM_006570 Ras-related GTP binding A RRAGA 10670 NM_006570 0006915 // apoptotic process // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032008 // positive regulation of TOR signaling // non-traceable author statement /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201629_s_at BE872974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE872974 /FEA=EST /DB_XREF=gi:10321660 /DB_XREF=est:601450667F1 /CLONE=IMAGE:3854584 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1 BE872974 acid phosphatase 1, soluble ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NM_177554 /// NR_024080 /// XR_426957 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201630_s_at NM_004300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004300.1 /DEF=Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant a, mRNA. /FEA=mRNA /GEN=ACP1 /PROD=acid phosphatase 1 isoform a /DB_XREF=gi:4757713 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1 NM_004300 acid phosphatase 1, soluble ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NM_177554 /// NR_024080 /// XR_426957 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201631_s_at NM_003897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003897.1 /DEF=Homo sapiens immediate early response 3 (IER3), mRNA. /FEA=mRNA /GEN=IER3 /PROD=immediate early response 3 /DB_XREF=gi:4503328 /UG=Hs.76095 immediate early response 3 /FL=gb:BC000844.1 gb:BC005080.1 gb:AF083421.1 gb:NM_003897.1 NM_003897 immediate early response 3 IER3 8870 NM_003897 /// NM_052815 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0001562 // response to protozoan // inferred from electronic annotation /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006282 // regulation of DNA repair // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201632_at NM_001414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001414.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) (EIF2B1), mRNA. /FEA=mRNA /GEN=EIF2B1 /PROD=eukaryotic translation initiation factor 2B,subunit 1 (alpha, 26kD) /DB_XREF=gi:4503502 /UG=Hs.78592 eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) /FL=gb:NM_001414.1 NM_001414 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa EIF2B1 1967 NM_001414 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // not recorded /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0032057 // negative regulation of translational initiation in response to stress // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 201633_s_at AW235051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW235051 /FEA=EST /DB_XREF=gi:6567440 /DB_XREF=est:xn18a09.x1 /CLONE=IMAGE:2694040 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1 AW235051 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201634_s_at NM_030579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030579.1 /DEF=Homo sapiens cytochrome b5 outer mitochondrial membrane precursor (CYB5-M), mRNA. /FEA=mRNA /GEN=CYB5-M /PROD=cytochrome b5 outer mitochondrial membraneprecursor /DB_XREF=gi:13385593 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1 NM_030579 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201635_s_at AI990766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI990766 /FEA=EST /DB_XREF=gi:5837647 /DB_XREF=est:ws23e06.x1 /CLONE=IMAGE:2498050 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 AI990766 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201636_at BG025078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG025078 /FEA=EST /DB_XREF=gi:12411309 /DB_XREF=est:602276425F1 /CLONE=IMAGE:4364070 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 BG025078 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201637_s_at NM_005087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005087.1 /DEF=Homo sapiens fragile X mental retardation, autosomal homolog 1 (FXR1), mRNA. /FEA=mRNA /GEN=FXR1 /PROD=fragile X mental retardation-related protein 1 /DB_XREF=gi:4826735 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 NM_005087 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201638_s_at BE676642 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE676642 /FEA=EST /DB_XREF=gi:10037183 /DB_XREF=est:7f33f02.x1 /CLONE=IMAGE:3296475 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1 BE676642 cleavage and polyadenylation specific factor 1, 160kDa CPSF1 29894 NM_013291 /// XM_006716548 /// XM_006716549 /// XM_006716550 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201639_s_at NM_013291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013291.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 1, 160kD subunit (CPSF1), mRNA. /FEA=mRNA /GEN=CPSF1 /PROD=cleavage and polyadenylation specific factor 1,160kD subunit /DB_XREF=gi:9558724 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1 NM_013291 cleavage and polyadenylation specific factor 1, 160kDa /// microRNA 1234 /// microRNA 6849 /// microRNA 939 CPSF1 /// MIR1234 /// MIR6849 /// MIR939 29894 /// 100126351 /// 100302196 /// 102466749 NM_013291 /// NR_030635 /// NR_031600 /// NR_106908 /// XM_006716548 /// XM_006716549 /// XM_006716550 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201640_x_at NM_001294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001294.1 /DEF=Homo sapiens cleft lip and palate associated transmembrane protein 1 (CLPTM1), mRNA. /FEA=mRNA /GEN=CLPTM1 /PROD=cleft lip and palate associated transmembraneprotein 1 /DB_XREF=gi:4502896 /UG=Hs.106671 cleft lip and palate associated transmembrane protein 1 /FL=gb:AF037339.1 gb:NM_001294.1 NM_001294 cleft lip and palate associated transmembrane protein 1 CLPTM1 1209 NM_001199468 /// NM_001282175 /// NM_001282176 /// NM_001294 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201641_at NM_004335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004335.2 /DEF=Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. /FEA=mRNA /GEN=BST2 /PROD=bone marrow stromal cell antigen 2 /DB_XREF=gi:7262372 /UG=Hs.118110 bone marrow stromal cell antigen 2 /FL=gb:D28137.1 gb:NM_004335.2 NM_004335 bone marrow stromal cell antigen 2 BST2 684 NM_004335 0002376 // immune system process // inferred from electronic annotation /// 0002737 // negative regulation of plasmacytoid dendritic cell cytokine production // inferred from direct assay /// 0006959 // humoral immune response // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0035455 // response to interferon-alpha // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from sequence or structural similarity /// 0042113 // B cell activation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 1901253 // negative regulation of intracellular transport of viral material // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201642_at NM_005534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005534.1 /DEF=Homo sapiens interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2), mRNA. /FEA=mRNA /GEN=IFNGR2 /PROD=interferon gamma receptor 2 (interferon gammatransducer 1) /DB_XREF=gi:5031782 /UG=Hs.177559 interferon gamma receptor 2 (interferon gamma transducer 1) /FL=gb:BC003624.1 gb:U05875.1 gb:U05877.1 gb:NM_005534.1 NM_005534 interferon gamma receptor 2 (interferon gamma transducer 1) IFNGR2 3460 NM_005534 /// XM_005260969 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004906 // interferon-gamma receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201643_x_at NM_016604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016604.1 /DEF=Homo sapiens putative zinc finger protein (LOC51780), mRNA. /FEA=mRNA /GEN=LOC51780 /PROD=putative zinc finger protein /DB_XREF=gi:7706598 /UG=Hs.24125 putative zinc finger protein /FL=gb:AF251039.1 gb:NM_016604.1 NM_016604 lysine (K)-specific demethylase 3B KDM3B 51780 NM_016604 /// XM_005272018 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 201644_at NM_003313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003313.2 /DEF=Homo sapiens tissue specific transplantation antigen P35B (TSTA3), mRNA. /FEA=mRNA /GEN=TSTA3 /PROD=tissue specific transplantation antigen P35B /DB_XREF=gi:6598326 /UG=Hs.264428 tissue specific transplantation antigen P35B /FL=gb:BC001941.1 gb:U58766.1 gb:NM_003313.2 NM_003313 tissue specific transplantation antigen P35B TSTA3 7264 NM_003313 /// XM_005251050 /// XM_005251051 /// XM_005251052 /// XM_006725093 /// XM_006725094 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019673 // GDP-mannose metabolic process // inferred from direct assay /// 0019835 // cytolysis // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from direct assay /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042356 // GDP-4-dehydro-D-rhamnose reductase activity // traceable author statement /// 0050577 // GDP-L-fucose synthase activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 201645_at NM_002160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002160.1 /DEF=Homo sapiens hexabrachion (tenascin C, cytotactin) (HXB), mRNA. /FEA=mRNA /GEN=HXB /PROD=hexabrachion (tenascin C, cytotactin) /DB_XREF=gi:4504548 /UG=Hs.289114 hexabrachion (tenascin C, cytotactin) /FL=gb:M55618.1 gb:NM_002160.1 NM_002160 tenascin C TNC 3371 NM_002160 /// XM_005251972 /// XM_005251973 /// XM_005251974 /// XM_005251975 /// XM_006717096 /// XM_006717097 /// XM_006717098 /// XM_006717099 /// XM_006717100 /// XM_006717101 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0060447 // bud outgrowth involved in lung branching // inferred from electronic annotation /// 0060739 // mesenchymal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0045545 // syndecan binding // inferred from physical interaction 201646_at AA885297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA885297 /FEA=EST /DB_XREF=gi:2994374 /DB_XREF=est:al58h03.s1 /CLONE=IMAGE:1461557 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1 AA885297 scavenger receptor class B, member 2 SCARB2 950 NM_001204255 /// NM_005506 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201647_s_at NM_005506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005506.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) (CD36L2), mRNA. /FEA=mRNA /GEN=CD36L2 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 2 (lysosomal integralmembrane protein II) /DB_XREF=gi:5031630 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1 NM_005506 scavenger receptor class B, member 2 SCARB2 950 NM_001204255 /// NM_005506 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201648_at AL039831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL039831 /FEA=EST /DB_XREF=gi:5935215 /DB_XREF=est:DKFZp434D1112_s1 /CLONE=DKFZp434D1112 /UG=Hs.50651 Janus kinase 1 (a protein tyrosine kinase) /FL=gb:M64174.1 gb:NM_002227.1 AL039831 Janus kinase 1 JAK1 3716 NM_002227 /// XM_005270841 /// XM_006710624 0006468 // protein phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038110 // interleukin-2-mediated signaling pathway // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005131 // growth hormone receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation 201649_at NM_004223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004223.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 6 (UBE2L6), mRNA. /FEA=mRNA /GEN=UBE2L6 /PROD=ubiquitin-conjugating enzyme E2L 6 /DB_XREF=gi:4759281 /UG=Hs.169895 ubiquitin-conjugating enzyme E2L 6 /FL=gb:AF031141.1 gb:AF061736.1 gb:NM_004223.1 NM_004223 ubiquitin-conjugating enzyme E2L 6 UBE2L6 9246 NM_004223 /// NM_198183 0006464 // cellular protein modification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // inferred from electronic annotation /// 0032020 // ISG15-protein conjugation // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0042296 // ISG15 ligase activity // inferred from electronic annotation 201650_at NM_002276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002276.1 /DEF=Homo sapiens keratin 19 (KRT19), mRNA. /FEA=mRNA /GEN=KRT19 /PROD=keratin 19 /DB_XREF=gi:4504916 /UG=Hs.182265 keratin 19 /FL=gb:BC002539.1 gb:NM_002276.1 NM_002276 keratin 19 KRT19 3880 NM_002276 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from expression pattern /// 0045214 // sarcomere organization // inferred from direct assay /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 201651_s_at NM_007229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007229.1 /DEF=Homo sapiens protein kinase C and casein kinase substrate in neurons 2 (PACSIN2), mRNA. /FEA=mRNA /GEN=PACSIN2 /PROD=protein kinase C and casein kinase substrate inneurons 2 /DB_XREF=gi:6005825 /UG=Hs.18842 protein kinase C and casein kinase substrate in neurons 2 /FL=gb:AF128536.1 gb:NM_007229.1 NM_007229 protein kinase C and casein kinase substrate in neurons 2 PACSIN2 11252 NM_001184970 /// NM_001184971 /// NM_007229 /// XM_005261319 /// XM_006724117 /// XM_006724118 /// XM_006724119 /// XM_006724120 0006897 // endocytosis // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // inferred from electronic annotation /// 0048858 // cell projection morphogenesis // inferred from sequence or structural similarity /// 0070836 // caveola assembly // inferred from mutant phenotype /// 0072584 // caveolin-mediated endocytosis // inferred from mutant phenotype /// 0097320 // membrane tubulation // inferred from direct assay /// 0097320 // membrane tubulation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070300 // phosphatidic acid binding // inferred from direct assay 201652_at NM_006837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006837.1 /DEF=Homo sapiens COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 (COPS5), mRNA. /FEA=mRNA /GEN=COPS5 /PROD=COP9 (constitutive photomorphogenic,Arabidopsis, homolog) subunit 5 /DB_XREF=gi:5803045 /UG=Hs.198767 COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 /FL=gb:BC001187.1 gb:BC001859.1 gb:U65928.1 gb:U70734.1 gb:NM_006837.1 NM_006837 COP9 signalosome subunit 5 COPS5 10987 NM_006837 0000338 // protein deneddylation // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0010388 // cullin deneddylation // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1990182 // exosomal secretion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0008021 // synaptic vesicle // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201653_at NM_005776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005776.1 /DEF=Homo sapiens cornichon-like (CNIL), mRNA. /FEA=mRNA /GEN=CNIL /PROD=cornichon-like /DB_XREF=gi:5031638 /UG=Hs.201673 cornichon-like /FL=gb:AF104398.1 gb:AF070654.1 gb:AF031379.1 gb:NM_005776.1 NM_005776 cornichon family AMPA receptor auxiliary protein 1 CNIH1 10175 NM_001009551 /// NM_005776 /// XR_245653 0006810 // transport // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201654_s_at AI991033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991033 /FEA=EST /DB_XREF=gi:5837930 /DB_XREF=est:wu36a08.x1 /CLONE=IMAGE:2522102 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2 AI991033 heparan sulfate proteoglycan 2 HSPG2 3339 NM_001291860 /// NM_005529 /// XM_005245863 /// XM_006710594 /// XM_006710595 /// XM_006710596 /// XM_006710597 /// XM_006710598 0001523 // retinoid metabolic process // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201655_s_at M85289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M85289.1 /DEF=Human heparan sulfate proteoglycan (HSPG2) mRNA, complete cds. /FEA=mRNA /GEN=HSPG2 /PROD=heparan sulfate proteoglycan /DB_XREF=gi:184426 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2 M85289 heparan sulfate proteoglycan 2 HSPG2 3339 NM_001291860 /// NM_005529 /// XM_005245863 /// XM_006710594 /// XM_006710595 /// XM_006710596 /// XM_006710597 /// XM_006710598 0001523 // retinoid metabolic process // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201656_at NM_000210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000210.1 /DEF=Homo sapiens integrin, alpha 6 (ITGA6), mRNA. /FEA=mRNA /GEN=ITGA6 /PROD=integrin alpha chain, alpha 6 /DB_XREF=gi:4557674 /UG=Hs.227730 integrin, alpha 6 /FL=gb:NM_000210.1 NM_000210 integrin, alpha 6 ITGA6 3655 NM_000210 /// NM_001079818 /// XM_006712510 /// XM_006712511 0007044 // cell-substrate junction assembly // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0034676 // integrin alpha6-beta4 complex // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201657_at BE890745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE890745 /FEA=EST /DB_XREF=gi:10349375 /DB_XREF=est:601431177F1 /CLONE=IMAGE:3916507 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 BE890745 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201658_at AU151560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151560 /FEA=EST /DB_XREF=gi:11013081 /DB_XREF=est:AU151560 /CLONE=NT2RP2005555 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 AU151560 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201659_s_at NM_001177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001177.2 /DEF=Homo sapiens ADP-ribosylation factor-like 1 (ARL1), mRNA. /FEA=mRNA /GEN=ARL1 /PROD=ADP-ribosylation factor-like 1 /DB_XREF=gi:4755126 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 NM_001177 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201660_at AL525798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL525798 /FEA=EST /DB_XREF=gi:12789291 /DB_XREF=est:AL525798 /CLONE=CS0DC013YB08 (5 prime) /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 AL525798 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201661_s_at NM_004457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004457.2 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 3 (FACL3), mRNA. /FEA=mRNA /GEN=FACL3 /PROD=long-chain fatty-acid-Coenzyme A ligase 3 /DB_XREF=gi:12669907 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 NM_004457 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201662_s_at D89053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89053.1 /DEF=Homo sapiens mRNA for Acyl-CoA synthetase 3, complete cds. /FEA=mRNA /PROD=Acyl-CoA synthetase 3 /DB_XREF=gi:4165017 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 D89053 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201663_s_at NM_005496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005496.1 /DEF=Homo sapiens chromosome-associated polypeptide C (CAP-C), mRNA. /FEA=mRNA /GEN=CAP-C /PROD=chromosome-associated polypeptide C /DB_XREF=gi:4885112 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1 NM_005496 structural maintenance of chromosomes 4 SMC4 10051 NM_001002799 /// NM_001002800 /// NM_001288753 /// NM_005496 /// XM_006713459 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201664_at AL136877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136877.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F205 (from clone DKFZp434F205); complete cds. /FEA=mRNA /GEN=DKFZp434F205 /PROD=hypothetical protein /DB_XREF=gi:6807670 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1 AL136877 structural maintenance of chromosomes 4 SMC4 10051 NM_001002799 /// NM_001002800 /// NM_001288753 /// NM_005496 /// XM_006713459 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201665_x_at NM_001021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001021.1 /DEF=Homo sapiens ribosomal protein S17 (RPS17), mRNA. /FEA=mRNA /GEN=RPS17 /PROD=ribosomal protein S17 /DB_XREF=gi:4506692 /UG=Hs.5174 ribosomal protein S17 /FL=gb:M13932.1 gb:NM_001021.1 NM_001021 ribosomal protein S17 RPS17 6218 NM_001021 /// NM_001199057 /// NR_111943 /// NR_111944 0000028 // ribosomal small subunit assembly // not recorded /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // not recorded /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201666_at NM_003254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003254.1 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) (TIMP1), mRNA. /FEA=mRNA /GEN=TIMP1 /PROD=tissue inhibitor of metalloproteinase 1precursor /DB_XREF=gi:4507508 /UG=Hs.5831 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) /FL=gb:BC000866.1 gb:M12670.1 gb:M59906.1 gb:NM_003254.1 NM_003254 TIMP metallopeptidase inhibitor 1 TIMP1 7076 NM_003254 /// XM_005272645 0001775 // cell activation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0048553 // negative regulation of metalloenzyme activity // inferred from direct assay /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 1901164 // negative regulation of trophoblast cell migration // inferred from mutant phenotype /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201667_at NM_000165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000165.2 /DEF=Homo sapiens gap junction protein, alpha 1, 43kD (connexin 43) (GJA1), mRNA. /FEA=mRNA /GEN=GJA1 /PROD=connexin 43 /DB_XREF=gi:4755136 /UG=Hs.74471 gap junction protein, alpha 1, 43kD (connexin 43) /FL=gb:M65188.1 gb:NM_000165.2 NM_000165 gap junction protein, alpha 1, 43kDa GJA1 2697 NM_000165 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0003104 // positive regulation of glomerular filtration // inferred from electronic annotation /// 0003158 // endothelium development // inferred from electronic annotation /// 0003294 // atrial ventricular junction remodeling // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0010232 // vascular transport // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from direct assay /// 0010652 // positive regulation of cell communication by chemical coupling // inferred from electronic annotation /// 0015867 // ATP transport // inferred from electronic annotation /// 0016264 // gap junction assembly // traceable author statement /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0034405 // response to fluid shear stress // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045844 // positive regulation of striated muscle tissue development // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046850 // regulation of bone remodeling // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060156 // milk ejection // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086014 // atrial cardiac muscle cell action potential // traceable author statement /// 2000810 // regulation of tight junction assembly // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005921 // gap junction // inferred from direct assay /// 0005921 // gap junction // inferred from sequence or structural similarity /// 0005922 // connexon complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from electronic annotation /// 0005243 // gap junction channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0071253 // connexin binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 201668_x_at AW163148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW163148 /FEA=EST /DB_XREF=gi:6302181 /DB_XREF=est:au92d06.y1 /CLONE=IMAGE:2783723 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 AW163148 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201669_s_at NM_002356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002356.4 /DEF=Homo sapiens myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) (MACS), mRNA. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich protein kinase Csubstrate /DB_XREF=gi:11125771 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 NM_002356 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201670_s_at M68956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M68956.1 /DEF=Human myristoylated alanine-rich C-kinase substrate mRNA, complete cds. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich C-kinase substrate /DB_XREF=gi:187386 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 M68956 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201671_x_at BC003556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003556.1 /DEF=Homo sapiens, ubiquitin specific protease 14 (tRNA-guanine transglycosylase), clone MGC:1453, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:13097695 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1 BC003556 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070628 // proteasome binding // inferred from direct assay 201672_s_at NM_005151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005151.1 /DEF=Homo sapiens ubiquitin specific protease 14 (tRNA-guanine transglycosylase) (USP14), mRNA. /FEA=mRNA /GEN=USP14 /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:4827049 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1 NM_005151 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070628 // proteasome binding // inferred from direct assay 201673_s_at NM_002103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002103.1 /DEF=Homo sapiens glycogen synthase 1 (muscle) (GYS1), mRNA. /FEA=mRNA /GEN=GYS1 /PROD=glycogen synthase 1 (muscle) /DB_XREF=gi:4504232 /UG=Hs.772 glycogen synthase 1 (muscle) /FL=gb:U32573.1 gb:BC002617.1 gb:J04501.1 gb:NM_002103.1 NM_002103 glycogen synthase 1 (muscle) GYS1 2997 NM_001161587 /// NM_002103 /// NR_027763 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from direct assay /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004373 // glycogen (starch) synthase activity // not recorded /// 0004373 // glycogen (starch) synthase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0061547 // glycogen synthase activity, transferring glucose-1-phosphate // not recorded 201674_s_at BC000729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000729.1 /DEF=Homo sapiens, A kinase (PRKA) anchor protein 1, clone MGC:1807, mRNA, complete cds. /FEA=mRNA /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:12653874 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1 BC000729 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201675_at NM_003488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003488.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 1 (AKAP1), mRNA. /FEA=mRNA /GEN=AKAP1 /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:4502014 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1 NM_003488 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201676_x_at NM_002786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002786.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), mRNA. /FEA=mRNA /GEN=PSMA1 /PROD=proteasome (prosome, macropain) subunit, alphatype, 1 /DB_XREF=gi:4506178 /UG=Hs.82159 proteasome (prosome, macropain) subunit, alpha type, 1 /FL=gb:BC002577.1 gb:NM_002786.1 NM_002786 proteasome (prosome, macropain) subunit, alpha type, 1 PSMA1 5682 NM_001143937 /// NM_002786 /// NM_148976 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005844 // polysome // traceable author statement /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201677_at AI937543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI937543 /FEA=EST /DB_XREF=gi:5676413 /DB_XREF=est:wp78f01.x1 /CLONE=IMAGE:2467897 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1 AI937543 5-hydroxymethylcytosine (hmC) binding, ES cell-specific HMCES 56941 NM_001006109 /// NM_020187 /// XM_005247636 /// XM_005247637 0006508 // proteolysis // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201678_s_at NM_020187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020187.1 /DEF=Homo sapiens DC12 protein (DC12), mRNA. /FEA=mRNA /GEN=DC12 /PROD=DC12 protein /DB_XREF=gi:9910181 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1 NM_020187 5-hydroxymethylcytosine (hmC) binding, ES cell-specific HMCES 56941 NM_001006109 /// NM_020187 /// XM_005247636 /// XM_005247637 0006508 // proteolysis // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201679_at BE646076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646076 /FEA=EST /DB_XREF=gi:9970376 /DB_XREF=est:7e92g12.x1 /CLONE=IMAGE:3292678 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 BE646076 serrate, RNA effector molecule SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201680_x_at NM_015908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015908.1 /DEF=Homo sapiens arsenate resistance protein ARS2 (ARS2), mRNA. /FEA=mRNA /GEN=ARS2 /PROD=arsenate resistance protein ARS2 /DB_XREF=gi:7706237 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 NM_015908 serrate, RNA effector molecule SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201681_s_at AB011155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011155.1 /DEF=Homo sapiens mRNA for KIAA0583 protein, partial cds. /FEA=mRNA /GEN=KIAA0583 /PROD=KIAA0583 protein /DB_XREF=gi:3043689 /UG=Hs.170290 discs, large (Drosophila) homolog 5 /FL=gb:U61843.1 gb:NM_004747.1 AB011155 discs, large homolog 5 (Drosophila) DLG5 9231 NM_004747 /// XM_005270276 /// XM_006718055 /// XM_006718056 /// XM_006718057 /// XM_006725120 /// XM_006725121 /// XM_006725122 /// XM_006725123 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 201682_at NM_004279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004279.1 /DEF=Homo sapiens peptidase (mitochondrial processing) beta (PMPCB), mRNA. /FEA=mRNA /GEN=PMPCB /PROD=peptidase (mitochondrial processing) beta /DB_XREF=gi:4758733 /UG=Hs.184211 peptidase (mitochondrial processing) beta /FL=gb:AF054182.1 gb:NM_004279.1 NM_004279 peptidase (mitochondrial processing) beta PMPCB 9512 NM_004279 /// XM_005250717 /// XM_006716181 /// XR_242267 0006508 // proteolysis // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201683_x_at BE783632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE783632 /FEA=EST /DB_XREF=gi:10204830 /DB_XREF=est:601471206F1 /CLONE=IMAGE:3874321 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BE783632 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201684_s_at BF001668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001668 /FEA=EST /DB_XREF=gi:10701943 /DB_XREF=est:7g91e03.x1 /CLONE=IMAGE:3313852 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BF001668 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201685_s_at NM_014828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014828.1 /DEF=Homo sapiens KIAA0737 gene product (KIAA0737), mRNA. /FEA=mRNA /GEN=KIAA0737 /PROD=KIAA0737 gene product /DB_XREF=gi:7662273 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 NM_014828 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201686_x_at AF229254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229254.1 /DEF=Homo sapiens clone FIF 504 fibroblast growth factor 2-interacting factor (API5) mRNA, complete cds. /FEA=mRNA /GEN=API5 /PROD=fibroblast growth factor 2-interacting factor /DB_XREF=gi:12656084 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1 AF229254 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201687_s_at NM_006595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006595.1 /DEF=Homo sapiens API5-like 1 (API5L1), mRNA. /FEA=mRNA /GEN=API5L1 /PROD=API5-like 1 /DB_XREF=gi:5729729 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1 NM_006595 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201688_s_at BG389015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG389015 /FEA=EST /DB_XREF=gi:13282461 /DB_XREF=est:602414790F1 /CLONE=IMAGE:4523087 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BG389015 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201689_s_at BE974098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE974098 /FEA=EST /DB_XREF=gi:10587434 /DB_XREF=est:601680437F1 /CLONE=IMAGE:3950697 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BE974098 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201690_s_at AA524023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524023 /FEA=EST /DB_XREF=gi:2264951 /DB_XREF=est:ng32e06.s1 /CLONE=IMAGE:936514 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 AA524023 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201691_s_at NM_005079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005079.1 /DEF=Homo sapiens tumor protein D52 (TPD52), mRNA. /FEA=mRNA /GEN=TPD52 /PROD=tumor protein D52 /DB_XREF=gi:4827037 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 NM_005079 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201692_at NM_005866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005866.1 /DEF=Homo sapiens sigma receptor (SR31747 binding protein 1) (SR-BP1), mRNA. /FEA=mRNA /GEN=SR-BP1 /PROD=sigma receptor (SR31747 binding protein 1) /DB_XREF=gi:5032116 /UG=Hs.24447 sigma receptor (SR31747 binding protein 1) /FL=gb:BC004899.1 gb:U75283.1 gb:U79528.1 gb:NM_005866.1 NM_005866 sigma non-opioid intracellular receptor 1 SIGMAR1 10280 NM_001282205 /// NM_001282206 /// NM_001282207 /// NM_001282208 /// NM_001282209 /// NM_005866 /// NM_147157 /// NM_147158 /// NM_147159 /// NM_147160 /// NR_104108 0006696 // ergosterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // traceable author statement 201693_s_at AV733950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV733950 /FEA=EST /DB_XREF=gi:10851495 /DB_XREF=est:AV733950 /CLONE=cdAADG12 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1 AV733950 early growth response 1 EGR1 1958 NM_001964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033233 // regulation of protein sumoylation // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // not recorded /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071317 // cellular response to isoquinoline alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // not recorded /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0072110 // glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 0072303 // positive regulation of glomerular metanephric mesangial cell proliferation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201694_s_at NM_001964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001964.1 /DEF=Homo sapiens early growth response 1 (EGR1), mRNA. /FEA=mRNA /GEN=EGR1 /PROD=early growth response 1 /DB_XREF=gi:4503492 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1 NM_001964 early growth response 1 EGR1 1958 NM_001964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033233 // regulation of protein sumoylation // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // not recorded /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071317 // cellular response to isoquinoline alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // not recorded /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0072110 // glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 0072303 // positive regulation of glomerular metanephric mesangial cell proliferation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201695_s_at NM_000270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000270.1 /DEF=Homo sapiens nucleoside phosphorylase (NP), mRNA. /FEA=mRNA /GEN=NP /PROD=purine nucleoside phosphorylase /DB_XREF=gi:4557800 /UG=Hs.75514 nucleoside phosphorylase /FL=gb:NM_000270.1 NM_000270 purine nucleoside phosphorylase PNP 4860 NM_000270 0006139 // nucleobase-containing compound metabolic process // inferred from direct assay /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006148 // inosine catabolic process // inferred from direct assay /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0034356 // NAD biosynthesis via nicotinamide riboside salvage pathway // inferred from genetic interaction /// 0034418 // urate biosynthetic process // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0070970 // interleukin-2 secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001882 // nucleoside binding // inferred from direct assay /// 0002060 // purine nucleobase binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // not recorded /// 0004731 // purine-nucleoside phosphorylase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from direct assay 201696_at NM_005626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005626.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 4 (SFRS4), mRNA. /FEA=mRNA /GEN=SFRS4 /PROD=splicing factor, arginineserine-rich 4 /DB_XREF=gi:5032088 /UG=Hs.76122 splicing factor, arginineserine-rich 4 /FL=gb:BC002781.1 gb:L14076.1 gb:NM_005626.1 NM_005626 serine/arginine-rich splicing factor 4 SRSF4 6429 NM_005626 /// XM_006710815 /// XM_006710816 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201697_s_at NM_001379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001379.1 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 1 (DNMT1), mRNA. /FEA=mRNA /GEN=DNMT1 /PROD=DNA (cytosine-5-)-methyltransferase 1 /DB_XREF=gi:4503350 /UG=Hs.77462 DNA (cytosine-5-)-methyltransferase 1 /FL=gb:NM_001379.1 NM_001379 DNA (cytosine-5-)-methyltransferase 1 DNMT1 1786 NM_001130823 /// NM_001379 /// XM_006722681 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0090116 // C-5 methylation of cytosine // inferred from electronic annotation 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005657 // replication fork // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0009008 // DNA-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201698_s_at NM_003769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1 NM_003769 glutamyl-tRNA(Gln) amidotransferase, subunit C /// serine/arginine-rich splicing factor 9 GATC /// SRSF9 8683 /// 283459 NM_003769 /// NM_176818 /// NR_033684 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 201699_at NM_002806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002806.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 6 (PSMC6), mRNA. /FEA=mRNA /GEN=PSMC6 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 6 /DB_XREF=gi:4506214 /UG=Hs.79357 proteasome (prosome, macropain) 26S subunit, ATPase, 6 /FL=gb:BC005390.1 gb:D78275.1 gb:AF006305.1 gb:NM_002806.1 NM_002806 proteasome (prosome, macropain) 26S subunit, ATPase, 6 PSMC6 5706 NM_002806 /// XR_245706 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred by curator /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0090261 // positive regulation of inclusion body assembly // inferred from electronic annotation 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 201700_at NM_001760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001760.1 /DEF=Homo sapiens cyclin D3 (CCND3), mRNA. /FEA=mRNA /GEN=CCND3 /PROD=cyclin D3 /DB_XREF=gi:4502618 /UG=Hs.83173 cyclin D3 /FL=gb:M90814.1 gb:M92287.1 gb:NM_001760.1 NM_001760 cyclin D3 CCND3 896 NM_001136017 /// NM_001136125 /// NM_001136126 /// NM_001287427 /// NM_001287434 /// NM_001760 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 201701_s_at NM_006320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006320.1 /DEF=Homo sapiens progesterone membrane binding protein (PMBP), mRNA. /FEA=mRNA /GEN=PMBP /PROD=progesterone membrane binding protein /DB_XREF=gi:5453915 /UG=Hs.9071 progesterone membrane binding protein /FL=gb:NM_006320.1 NM_006320 progesterone receptor membrane component 2 PGRMC2 10424 NM_006320 0043401 // steroid hormone mediated signaling pathway // traceable author statement 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003707 // steroid hormone receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201702_s_at AI492873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI492873 /FEA=EST /DB_XREF=gi:4393876 /DB_XREF=est:th78b05.x1 /CLONE=IMAGE:2124753 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1 AI492873 protein phosphatase 1, regulatory subunit 10 PPP1R10 5514 NM_002714 /// NR_072994 /// XM_006715130 /// XM_006715131 /// XM_006715132 /// XM_006715133 /// XM_006725489 /// XM_006725490 /// XM_006725491 /// XM_006725492 /// XM_006725703 /// XM_006725704 /// XM_006725705 /// XM_006725706 /// XM_006725820 /// XM_006725821 /// XM_006725822 /// XM_006725823 /// XM_006725912 /// XM_006725913 /// XM_006725914 /// XM_006725915 /// XM_006726005 /// XM_006726006 /// XM_006726007 /// XM_006726008 /// XM_006726100 /// XM_006726101 /// XM_006726102 /// XM_006726103 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201703_s_at NM_002714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002714.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 10 (PPP1R10), mRNA. /FEA=mRNA /GEN=PPP1R10 /PROD=protein phosphatase 1, regulatory subunit 10 /DB_XREF=gi:4506008 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1 NM_002714 protein phosphatase 1, regulatory subunit 10 PPP1R10 5514 NM_002714 /// NR_072994 /// XM_006715130 /// XM_006715131 /// XM_006715132 /// XM_006715133 /// XM_006725489 /// XM_006725490 /// XM_006725491 /// XM_006725492 /// XM_006725703 /// XM_006725704 /// XM_006725705 /// XM_006725706 /// XM_006725820 /// XM_006725821 /// XM_006725822 /// XM_006725823 /// XM_006725912 /// XM_006725913 /// XM_006725914 /// XM_006725915 /// XM_006726005 /// XM_006726006 /// XM_006726007 /// XM_006726008 /// XM_006726100 /// XM_006726101 /// XM_006726102 /// XM_006726103 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201704_at NM_001247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001247.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 6 (putative function) (ENTPD6), mRNA. /FEA=mRNA /GEN=ENTPD6 /PROD=ectonucleoside triphosphate diphosphohydrolase 6(putative function) /DB_XREF=gi:4557422 /UG=Hs.12330 ectonucleoside triphosphate diphosphohydrolase 6 (putative function) /FL=gb:AF039916.1 gb:NM_001247.1 NM_001247 ectonucleoside triphosphate diphosphohydrolase 6 (putative) ENTPD6 955 NM_001114089 /// NM_001247 /// XM_005260878 /// XM_005260881 /// XM_005260882 /// XM_005260883 /// XM_005260884 /// XM_005260885 /// XM_005260886 /// XM_005260887 /// XM_006723665 /// XM_006723666 0008152 // metabolic process // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008894 // guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from electronic annotation 201705_at NM_002811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002811.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA. /FEA=mRNA /GEN=PSMD7 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 7 (Mov34 homolog) /DB_XREF=gi:4506230 /UG=Hs.155543 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) /FL=gb:NM_002811.1 gb:D50063.1 NM_002811 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 PSMD7 5713 NM_002811 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201706_s_at BC000496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000496.1 /DEF=Homo sapiens, peroxisomal farnesylated protein, clone MGC:8403, mRNA, complete cds. /FEA=mRNA /PROD=peroxisomal farnesylated protein /DB_XREF=gi:12653448 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1 BC000496 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_001193644 /// NM_002857 /// NR_036492 /// NR_036493 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007031 // peroxisome organization // non-traceable author statement /// 0016557 // peroxisome membrane biogenesis // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0045046 // protein import into peroxisome membrane // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 0072663 // establishment of protein localization to peroxisome // inferred from mutant phenotype /// 1900131 // negative regulation of lipid binding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0036105 // peroxisome membrane class-1 targeting sequence binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 201707_at NM_002857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002857.1 /DEF=Homo sapiens peroxisomal farnesylated protein (PXF), mRNA. /FEA=mRNA /GEN=PXF /PROD=peroxisomal farnesylated protein /DB_XREF=gi:4506338 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1 NM_002857 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_001193644 /// NM_002857 /// NR_036492 /// NR_036493 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007031 // peroxisome organization // non-traceable author statement /// 0016557 // peroxisome membrane biogenesis // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0045046 // protein import into peroxisome membrane // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 0072663 // establishment of protein localization to peroxisome // inferred from mutant phenotype /// 1900131 // negative regulation of lipid binding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0036105 // peroxisome membrane class-1 targeting sequence binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 201708_s_at AW083371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW083371 /FEA=EST /DB_XREF=gi:6038609 /DB_XREF=est:xc09g02.x1 /CLONE=IMAGE:2583794 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1 AW083371 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_001202502 /// NM_003634 /// XM_005261789 0019233 // sensory perception of pain // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 201709_s_at NM_003634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003634.1 /DEF=Homo sapiens NIPSNAP, C. elegans, homolog 1 (NIPSNAP1), mRNA. /FEA=mRNA /GEN=NIPSNAP1 /PROD=NIPSNAP, C. elegans, homolog 1 /DB_XREF=gi:4505398 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1 NM_003634 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_001202502 /// NM_003634 /// XM_005261789 0019233 // sensory perception of pain // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 201710_at NM_002466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002466.1 /DEF=Homo sapiens v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2), mRNA. /FEA=mRNA /GEN=MYBL2 /PROD=v-myb avian myeloblastosis viral oncogenehomolog-like 2 /DB_XREF=gi:4505292 /UG=Hs.179718 v-myb avian myeloblastosis viral oncogene homolog-like 2 /FL=gb:NM_002466.1 NM_002466 v-myb avian myeloblastosis viral oncogene homolog-like 2 MYBL2 4605 NM_001278610 /// NM_002466 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031523 // Myb complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201711_x_at AI681120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI681120 /FEA=EST /DB_XREF=gi:4891302 /DB_XREF=est:tx44b06.x1 /CLONE=IMAGE:2272403 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 AI681120 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201712_s_at NM_006267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006267.2 /DEF=Homo sapiens RAN binding protein 2 (RANBP2), mRNA. /FEA=mRNA /GEN=RANBP2 /PROD=RAN binding protein 2 /DB_XREF=gi:6382078 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 NM_006267 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201713_s_at D42063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D42063.1 /DEF=Human mRNA for RanBP2 (Ran-binding protein 2), complete cds. /FEA=mRNA /PROD=RanBP2 (Ran-binding protein 2) /DB_XREF=gi:924266 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 D42063 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201714_at NM_001070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001070.1 /DEF=Homo sapiens tubulin, gamma 1 (TUBG1), mRNA. /FEA=mRNA /GEN=TUBG1 /PROD=tubulin, gamma 1 /DB_XREF=gi:4507730 /UG=Hs.21635 tubulin, gamma 1 /FL=gb:BC000619.1 gb:M61764.1 gb:NM_001070.1 NM_001070 tubulin, gamma 1 TUBG1 7283 NM_001070 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000212 // meiotic spindle organization // inferred from sequence or structural similarity /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007020 // microtubule nucleation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0000930 // gamma-tubulin complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201715_s_at NM_014977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014977.1 /DEF=Homo sapiens KIAA0670 proteinacinus (KIAA0670), mRNA. /FEA=mRNA /GEN=KIAA0670 /PROD=KIAA0670 proteinacinus /DB_XREF=gi:7662237 /UG=Hs.227133 KIAA0670 proteinacinus /FL=gb:AF124726.1 gb:NM_014977.1 NM_014977 apoptotic chromatin condensation inducer 1 ACIN1 22985 NM_001164814 /// NM_001164815 /// NM_001164816 /// NM_001164817 /// NM_014977 /// XM_005267415 /// XM_005267416 /// XM_005267418 /// XM_006720081 /// XR_429295 /// XR_429296 /// XR_429297 0006200 // ATP catabolic process // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from expression pattern /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0061574 // ASAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // non-traceable author statement /// 0019899 // enzyme binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201716_at NM_003099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003099.1 /DEF=Homo sapiens sorting nexin 1 (SNX1), mRNA. /FEA=mRNA /GEN=SNX1 /PROD=sorting nexin 1 /DB_XREF=gi:4507138 /UG=Hs.75283 sorting nexin 1 /FL=gb:BC000357.1 gb:U53225.1 gb:AF065483.1 gb:NM_003099.1 NM_003099 sorting nexin 1 SNX1 6642 NM_001242933 /// NM_003099 /// NM_148955 /// NM_152826 /// XM_005254610 /// XM_005254611 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 201717_at NM_004927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004927.1 /DEF=Homo sapiens chromosome 11 open reading frame 4 (C11ORF4), mRNA. /FEA=mRNA /GEN=C11ORF4 /PROD=chromosome 11 open reading frame 4 /DB_XREF=gi:4826648 /UG=Hs.75859 chromosome 11 open reading frame 4 /FL=gb:U39400.1 gb:BC004378.1 gb:NM_004927.1 NM_004927 mitochondrial ribosomal protein L49 MRPL49 740 NM_004927 /// NR_037567 /// NR_037568 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201718_s_at BF511685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511685 /FEA=EST /DB_XREF=gi:11594983 /DB_XREF=est:UI-H-BI4-aom-c-09-0-UI.s1 /CLONE=IMAGE:3085432 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1 BF511685 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001199388 /// NM_001199389 /// NM_001252660 /// NM_001431 /// XM_005266840 /// XM_005266841 /// XM_006715356 /// XM_006715357 /// XM_006715358 /// XM_006715359 /// XM_006715360 /// XM_006715361 /// XM_006715362 /// XM_006715363 /// XM_006715364 /// XM_006715365 /// XM_006715366 /// XM_006715367 /// XM_006715368 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from electronic annotation 201719_s_at NM_001431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001431.1 /DEF=Homo sapiens erythrocyte membrane protein band 4.1-like 2 (EPB41L2), mRNA. /FEA=mRNA /GEN=EPB41L2 /PROD=erythrocyte membrane protein band 4.1-like 2 /DB_XREF=gi:4503578 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1 NM_001431 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001199388 /// NM_001199389 /// NM_001252660 /// NM_001431 /// XM_005266840 /// XM_005266841 /// XM_006715356 /// XM_006715357 /// XM_006715358 /// XM_006715359 /// XM_006715360 /// XM_006715361 /// XM_006715362 /// XM_006715363 /// XM_006715364 /// XM_006715365 /// XM_006715366 /// XM_006715367 /// XM_006715368 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from electronic annotation 201720_s_at AI589086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI589086 /FEA=EST /DB_XREF=gi:4598134 /DB_XREF=est:tf80g10.x1 /CLONE=IMAGE:2105634 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1 AI589086 lysosomal protein transmembrane 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201721_s_at NM_006762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006762.1 /DEF=Homo sapiens Lysosomal-associated multispanning membrane protein-5 (LAPTM5), mRNA. /FEA=mRNA /GEN=LAPTM5 /PROD=Lysosomal-associated multispanning membraneprotein-5 /DB_XREF=gi:5803055 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1 NM_006762 lysosomal protein transmembrane 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201722_s_at AV692127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV692127 /FEA=EST /DB_XREF=gi:10293990 /DB_XREF=est:AV692127 /CLONE=GKCAOB04 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 AV692127 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201723_s_at U41514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U41514.1 /DEF=Human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA, complete cds. /FEA=mRNA /PROD=UDP-GalNAc:polypeptideN-acetylgalactosaminyltransferase /DB_XREF=gi:1136284 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 U41514 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201724_s_at NM_020474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020474.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1), mRNA. /FEA=mRNA /GEN=GALNT1 /PROD=polypeptide N-acetylgalactosaminyltransferase 1 /DB_XREF=gi:13124890 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 NM_020474 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201725_at NM_006023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006023.1 /DEF=Homo sapiens D123 gene product (D123), mRNA. /FEA=mRNA /GEN=D123 /PROD=D123 gene product /DB_XREF=gi:5174422 /UG=Hs.82043 D123 gene product /FL=gb:BC001600.1 gb:D14878.1 gb:U27112.1 gb:NM_006023.1 NM_006023 cell division cycle 123 CDC123 8872 NM_006023 /// XM_005252638 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 201726_at BC003376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003376.1 /DEF=Homo sapiens, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), clone MGC:5084, mRNA, complete cds. /FEA=mRNA /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:13097227 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1 BC003376 ELAV like RNA binding protein 1 ELAVL1 1994 NM_001419 /// XR_430131 0006417 // regulation of translation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201727_s_at NM_001419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001419.1 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mRNA. /FEA=mRNA /GEN=ELAVL1 /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:4503550 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1 NM_001419 ELAV like RNA binding protein 1 ELAVL1 1994 NM_001419 /// XR_430131 0006417 // regulation of translation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201728_s_at AA904674 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA904674 /FEA=EST /DB_XREF=gi:3039797 /DB_XREF=est:oj73f02.s1 /CLONE=IMAGE:1503963 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1 AA904674 KIAA0100 KIAA0100 9703 NM_014680 /// XM_005258073 /// XM_006722198 /// XR_429933 0005576 // extracellular region // inferred from electronic annotation 201729_s_at NM_014680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014680.1 /DEF=Homo sapiens KIAA0100 gene product (KIAA0100), mRNA. /FEA=mRNA /GEN=KIAA0100 /PROD=KIAA0100 gene product /DB_XREF=gi:7661903 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1 NM_014680 KIAA0100 KIAA0100 9703 NM_014680 /// XM_005258073 /// XM_006722198 /// XR_429933 0005576 // extracellular region // inferred from electronic annotation 201730_s_at BF110993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110993 /FEA=EST /DB_XREF=gi:10940683 /DB_XREF=est:7n42e09.x1 /CLONE=IMAGE:3567448 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1 BF110993 translocated promoter region, nuclear basket protein TPR 7175 NM_003292 /// XM_005245471 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0009318 // exodeoxyribonuclease VII complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008855 // exodeoxyribonuclease VII activity // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 201731_s_at NM_003292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003292.1 /DEF=Homo sapiens translocated promoter region (to activated MET oncogene) (TPR), mRNA. /FEA=mRNA /GEN=TPR /PROD=translocated promoter region (to activated METoncogene) /DB_XREF=gi:4507658 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1 NM_003292 translocated promoter region, nuclear basket protein TPR 7175 NM_003292 /// XM_005245471 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0009318 // exodeoxyribonuclease VII complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008855 // exodeoxyribonuclease VII activity // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 201732_s_at AF029346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF029346.1 /DEF=Homo sapiens chloride channel protein 3 (CLCN3) mRNA, complete cds. /FEA=CDS /GEN=CLCN3 /PROD=chloride channel protein 3 /DB_XREF=gi:2599547 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AF029346 chloride channel, voltage-sensitive 3 CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201733_at AA902971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA902971 /FEA=EST /DB_XREF=gi:3038094 /DB_XREF=est:ok44c09.s1 /CLONE=IMAGE:1516816 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AA902971 chloride channel, voltage-sensitive 3 CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201734_at AI760629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760629 /FEA=EST /DB_XREF=gi:5176296 /DB_XREF=est:wi66e06.x1 /CLONE=IMAGE:2398306 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AI760629 chloride channel, voltage-sensitive 3 CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201735_s_at NM_001829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001829.1 /DEF=Homo sapiens chloride channel 3 (CLCN3), mRNA. /FEA=mRNA /GEN=CLCN3 /PROD=chloride channel 3 /DB_XREF=gi:4502868 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 NM_001829 chloride channel, voltage-sensitive 3 CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201736_s_at BF000409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF000409 /FEA=EST /DB_XREF=gi:10700684 /DB_XREF=est:7h27h07.x1 /CLONE=IMAGE:3317245 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1 BF000409 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201737_s_at NM_005885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005885.1 /DEF=Homo sapiens similar to S. cerevisiae SSM4 (TEB4), mRNA. /FEA=mRNA /GEN=TEB4 /PROD=similar to S. cerevisiae SSM4 /DB_XREF=gi:5032166 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1 NM_005885 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201738_at NM_005875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005875.1 /DEF=Homo sapiens translation factor sui1 homolog (GC20), mRNA. /FEA=mRNA /GEN=GC20 /PROD=translation factor sui1 homolog /DB_XREF=gi:5031710 /UG=Hs.21756 translation factor sui1 homolog /FL=gb:AF064607.1 gb:AF077052.1 gb:NM_005875.1 gb:AF263452.1 NM_005875 eukaryotic translation initiation factor 1B EIF1B 10289 NM_005875 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // non-traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201739_at NM_005627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005627.1 /DEF=Homo sapiens serumglucocorticoid regulated kinase (SGK), mRNA. /FEA=mRNA /GEN=SGK /PROD=serumglucocorticoid regulated kinase /DB_XREF=gi:5032090 /UG=Hs.296323 serumglucocorticoid regulated kinase /FL=gb:BC001263.1 gb:NM_005627.1 gb:AF153609.1 NM_005627 serum/glucocorticoid regulated kinase 1 SGK1 6446 NM_001143676 /// NM_001143677 /// NM_001143678 /// NM_001291995 /// NM_005627 0001558 // regulation of cell growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007616 // long-term memory // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0032411 // positive regulation of transporter activity // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060453 // regulation of gastric acid secretion // traceable author statement /// 0070294 // renal sodium ion absorption // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // traceable author statement /// 0017081 // chloride channel regulator activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 201740_at NM_004551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004551.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) (NDUFS3), mRNA. /FEA=mRNA /GEN=NDUFS3 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 3(30kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758787 /UG=Hs.5273 NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) /FL=gb:BC000617.1 gb:AF067139.1 gb:NM_004551.1 gb:AF100743.1 NM_004551 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) NDUFS3 4722 NM_004551 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation 201741_x_at M69040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M69040.1 /DEF=Human SF2p33 mRNA, complete cds. /FEA=mRNA /PROD=SF2p33 /DB_XREF=gi:338046 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1 M69040 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201742_x_at NM_006924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006924.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) (SFRS1), mRNA. /FEA=mRNA /GEN=SFRS1 /PROD=splicing factor, arginineserine-rich 1(splicing factor 2, alternate splicing factor) /DB_XREF=gi:5902075 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1 NM_006924 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201743_at NM_000591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000591.1 /DEF=Homo sapiens CD14 antigen (CD14), mRNA. /FEA=mRNA /GEN=CD14 /PROD=CD14 antigen precursor /DB_XREF=gi:4557416 /UG=Hs.75627 CD14 antigen /FL=gb:M86511.1 gb:AF097942.1 gb:NM_000591.1 NM_000591 CD14 molecule CD14 929 NM_000591 /// NM_001040021 /// NM_001174104 /// NM_001174105 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006909 // phagocytosis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001847 // opsonin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016019 // peptidoglycan receptor activity // traceable author statement /// 0070891 // lipoteichoic acid binding // inferred from direct assay 201744_s_at NM_002345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002345.1 /DEF=Homo sapiens lumican (LUM), mRNA. /FEA=mRNA /GEN=LUM /PROD=lumican /DB_XREF=gi:4505046 /UG=Hs.79914 lumican /FL=gb:NM_002345.1 gb:U18728.1 gb:U21128.1 NM_002345 lumican LUM 4060 NM_002345 0005975 // carbohydrate metabolic process // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay 201745_at NM_002822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002822.1 /DEF=Homo sapiens protein tyrosine kinase 9 (PTK9), mRNA. /FEA=mRNA /GEN=PTK9 /PROD=protein tyrosine kinase 9 /DB_XREF=gi:4506274 /UG=Hs.82643 protein tyrosine kinase 9 /FL=gb:NM_002822.1 gb:U02680.1 NM_002822 twinfilin actin-binding protein 1 TWF1 5756 NM_001242397 /// NM_002822 /// NM_198974 /// NR_073472 /// NR_073473 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0043538 // regulation of actin phosphorylation // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity 201746_at NM_000546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000546.2 /DEF=Homo sapiens tumor protein p53 (Li-Fraumeni syndrome) (TP53), mRNA. /FEA=mRNA /GEN=TP53 /PROD=tumor protein p53 /DB_XREF=gi:8400737 /UG=Hs.1846 tumor protein p53 (Li-Fraumeni syndrome) /FL=gb:AF307851.1 gb:BC003596.1 gb:M14694.1 gb:M14695.1 gb:NM_000546.2 NM_000546 tumor protein p53 TP53 7157 NM_000546 /// NM_001126112 /// NM_001126113 /// NM_001126114 /// NM_001126115 /// NM_001126116 /// NM_001126117 /// NM_001126118 /// NM_001276695 /// NM_001276696 /// NM_001276697 /// NM_001276698 /// NM_001276699 /// NM_001276760 /// NM_001276761 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0007369 // gastrulation // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from direct assay /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0009303 // rRNA transcription // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010332 // response to gamma radiation // inferred from mutant phenotype /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // not recorded /// 0031497 // chromatin assembly // inferred from direct assay /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034103 // regulation of tissue remodeling // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0034644 // cellular response to UV // not recorded /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046902 // regulation of mitochondrial membrane permeability // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051097 // negative regulation of helicase activity // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090343 // positive regulation of cell aging // inferred from electronic annotation /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097252 // oligodendrocyte apoptotic process // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901525 // negative regulation of macromitophagy // inferred from electronic annotation /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // not recorded /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from physical interaction /// 0097371 // MDM2/MDM4 family protein binding // inferred from electronic annotation 201747_s_at AI769566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769566 /FEA=EST /DB_XREF=gi:5236075 /DB_XREF=est:wj24e11.x1 /CLONE=IMAGE:2403788 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1 AI769566 scaffold attachment factor B SAFB 6294 NM_001201338 /// NM_001201339 /// NM_001201340 /// NM_002967 /// NR_037699 /// XM_006722839 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201748_s_at NM_002967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002967.1 /DEF=Homo sapiens scaffold attachment factor B (SAFB), mRNA. /FEA=mRNA /GEN=SAFB /PROD=scaffold attachment factor B /DB_XREF=gi:4506778 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1 NM_002967 scaffold attachment factor B SAFB 6294 NM_001201338 /// NM_001201339 /// NM_001201340 /// NM_002967 /// NR_037699 /// XM_006722839 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201749_at BF969352 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF969352 /FEA=EST /DB_XREF=gi:12336567 /DB_XREF=est:602271616F1 /CLONE=IMAGE:4359794 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1 BF969352 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 /// XM_006710398 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0010814 // substance P catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010816 // calcitonin catabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031302 // intrinsic component of endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201750_s_at NM_001397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001397.1 /DEF=Homo sapiens endothelin converting enzyme 1 (ECE1), mRNA. /FEA=mRNA /GEN=ECE1 /PROD=endothelin converting enzyme 1 /DB_XREF=gi:4503442 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1 NM_001397 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 /// XM_006710398 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0010814 // substance P catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010816 // calcitonin catabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031302 // intrinsic component of endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201751_at NM_014876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014876.1 /DEF=Homo sapiens KIAA0063 gene product (KIAA0063), mRNA. /FEA=mRNA /GEN=KIAA0063 /PROD=KIAA0063 gene product /DB_XREF=gi:7661887 /UG=Hs.3094 KIAA0063 gene product /FL=gb:D31884.1 gb:NM_014876.1 NM_014876 Josephin domain containing 1 JOSD1 9929 NM_014876 /// XM_005261876 /// XM_005261877 /// XM_005261878 /// XM_005261879 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201752_s_at AI763123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI763123 /FEA=EST /DB_XREF=gi:5178790 /DB_XREF=est:wi06f09.x1 /CLONE=IMAGE:2389481 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1 AI763123 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201753_s_at NM_019903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019903.1 /DEF=Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 2, mRNA. /FEA=mRNA /GEN=ADD3 /PROD=adducin 3, isoform b /DB_XREF=gi:9951926 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1 NM_019903 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201754_at NM_004374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004374.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIc (COX6C), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6C /PROD=cytochrome c oxidase subunit VIc /DB_XREF=gi:4758039 /UG=Hs.74649 cytochrome c oxidase subunit VIc /FL=gb:BC000187.1 gb:NM_004374.1 NM_004374 cytochrome c oxidase subunit VIc COX6C 1345 NM_004374 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201755_at NM_006739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006739.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) (MCM5), mRNA. /FEA=mRNA /GEN=MCM5 /PROD=minichromosome maintenance deficient (S.cerevisiae) 5 (cell division cycle 46) /DB_XREF=gi:6981191 /UG=Hs.77171 minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) /FL=gb:D83986.1 gb:BC000142.1 gb:BC003656.1 gb:NM_006739.1 NM_006739 minichromosome maintenance complex component 5 MCM5 4174 NM_006739 /// XM_006724242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201756_at NM_002946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002946.1 /DEF=Homo sapiens replication protein A2 (32kD) (RPA2), mRNA. /FEA=mRNA /GEN=RPA2 /PROD=replication protein A2 (32kD) /DB_XREF=gi:4506584 /UG=Hs.79411 replication protein A2 (32kD) /FL=gb:BC001630.1 gb:J05249.1 gb:NM_002946.1 NM_002946 replication protein A2, 32kDa RPA2 6118 NM_001286076 /// NM_002946 /// XM_005245965 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred by curator /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from electronic annotation 201757_at NM_004552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004552.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) (NDUFS5), mRNA. /FEA=mRNA /GEN=NDUFS5 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 5(15kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758789 /UG=Hs.80595 NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) /FL=gb:BC001884.1 gb:AF020352.1 gb:AF047434.1 gb:NM_004552.1 NM_004552 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) /// ribosomal protein L10 NDUFS5 /// RPL10 4725 /// 6134 NM_001184979 /// NM_001256577 /// NM_001256580 /// NM_004552 /// NM_006013 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201758_at NM_006292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006292.1 /DEF=Homo sapiens tumor susceptibility gene 101 (TSG101), mRNA. /FEA=mRNA /GEN=TSG101 /PROD=tumor susceptibility gene 101 /DB_XREF=gi:5454139 /UG=Hs.118910 tumor susceptibility gene 101 /FL=gb:BC002487.1 gb:U82130.1 gb:NM_006292.1 NM_006292 tumor susceptibility 101 TSG101 7251 NM_006292 /// XM_005253107 /// XM_005253108 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046755 // viral budding // inferred from mutant phenotype /// 0046755 // viral budding // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201759_at AW247323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW247323 /FEA=EST /DB_XREF=gi:6590316 /DB_XREF=est:2819524.3prime /CLONE=IMAGE:2819524 /UG=Hs.12570 tubulin-specific chaperone d /FL=gb:BC003094.1 gb:AB023205.1 gb:NM_005993.2 AW247323 tubulin folding cofactor D TBCD 6904 NM_001033052 /// NM_005993 /// XM_005256396 /// XM_005256399 /// XM_005256400 /// XM_005256401 /// XM_005256402 /// XM_005256403 /// XM_005256404 /// XM_005256405 /// XM_006722290 /// XM_006722291 /// XM_006722292 /// XR_430033 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0034333 // adherens junction assembly // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 201760_s_at NM_018639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018639.1 /DEF=Homo sapiens CS box-containing WD protein (LOC55884), mRNA. /FEA=mRNA /GEN=LOC55884 /PROD=CS box-containing WD protein /DB_XREF=gi:8923880 /UG=Hs.136644 CS box-containing WD protein /FL=gb:AF229181.1 gb:AF163324.1 gb:NM_018639.1 NM_018639 WD repeat and SOCS box containing 2 WSB2 55884 NM_001278557 /// NM_001278558 /// NM_018639 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201761_at NM_006636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006636.2 /DEF=Homo sapiens methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (MTHFD2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTHFD2 /PROD=methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase,precursor /DB_XREF=gi:13699869 /UG=Hs.154672 methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase /FL=gb:NM_006636.2 NM_006636 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase MTHFD2 10797 NM_001040409 /// NM_006636 /// NR_027405 /// XM_006711924 0006730 // one-carbon metabolic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // inferred from sequence or structural similarity /// 0004487 // methylenetetrahydrofolate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from direct assay 201762_s_at NM_002818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002818.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (PSME2), mRNA. /FEA=mRNA /GEN=PSME2 /PROD=proteasome (prosome, macropain) activatorsubunit 2 (PA28 beta) /DB_XREF=gi:4506236 /UG=Hs.179774 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) /FL=gb:D45248.1 gb:BC004368.1 gb:NM_002818.1 NM_002818 microRNA 7703 /// proteasome (prosome, macropain) activator subunit 2 (PA28 beta) MIR7703 /// PSME2 5721 /// 102465801 NM_002818 /// NR_106990 /// XM_006720212 /// XM_006720213 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201763_s_at NM_001350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001350.1 /DEF=Homo sapiens death-associated protein 6 (DAXX), mRNA. /FEA=mRNA /GEN=DAXX /PROD=death-associated protein 6 /DB_XREF=gi:4503256 /UG=Hs.180224 death-associated protein 6 /FL=gb:AF015956.2 gb:AF039136.1 gb:AF050179.1 gb:AF097742.1 gb:AB015051.1 gb:NM_001350.1 NM_001350 death-domain associated protein DAXX 1616 NM_001141969 /// NM_001141970 /// NM_001254717 /// NM_001350 /// XM_005248860 /// XM_005275218 /// XM_005275354 0000281 // mitotic cytokinesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from genetic interaction /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 1901216 // positive regulation of neuron death // inferred from genetic interaction /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0031072 // heat shock protein binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 201764_at NM_024056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024056.1 /DEF=Homo sapiens hypothetical protein MGC5576 (MGC5576), mRNA. /FEA=mRNA /GEN=MGC5576 /PROD=hypothetical protein MGC5576 /DB_XREF=gi:13129025 /UG=Hs.103834 hypothetical protein MGC5576 /FL=gb:BC000854.1 gb:NM_024056.1 NM_024056 transmembrane protein 106C TMEM106C 79022 NM_001143841 /// NM_001143842 /// NM_001143843 /// NM_001143844 /// NM_001143845 /// NM_024056 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201765_s_at AL523158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523158 /FEA=EST /DB_XREF=gi:12786651 /DB_XREF=est:AL523158 /CLONE=CS0DC001YM06 (3 prime) /UG=Hs.119403 hexosaminidase A (alpha polypeptide) /FL=gb:NM_000520.2 AL523158 hexosaminidase A (alpha polypeptide) HEXA 3073 NM_000520 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201766_at AF304370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF304370.1 /DEF=Homo sapiens putative prostate cancer susceptibility protein HPC2ELAC2 mRNA, complete cds. /FEA=mRNA /PROD=putative prostate cancer susceptibility proteinHPC2ELAC2 /DB_XREF=gi:10880932 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1 AF304370 elaC ribonuclease Z 2 ELAC2 60528 NM_001165962 /// NM_018127 /// NM_173717 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0072684 // mitochondrial tRNA 3'-trailer cleavage, endonucleolytic // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201767_s_at NM_018127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018127.2 /DEF=Homo sapiens putative prostate cancer susceptibility protein (HPC2), mRNA. /FEA=mRNA /GEN=HPC2 /PROD=putative prostate cancer susceptibility protein /DB_XREF=gi:11875212 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1 NM_018127 elaC ribonuclease Z 2 ELAC2 60528 NM_001165962 /// NM_018127 /// NM_173717 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0072684 // mitochondrial tRNA 3'-trailer cleavage, endonucleolytic // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201768_s_at BC004467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004467.1 /DEF=Homo sapiens, KIAA0171 gene product, clone MGC:10257, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0171 gene product /DB_XREF=gi:13325306 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1 BC004467 clathrin interactor 1 CLINT1 9685 NM_001195555 /// NM_001195556 /// NM_014666 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction 201769_at NM_014666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014666.1 /DEF=Homo sapiens KIAA0171 gene product (KIAA0171), mRNA. /FEA=mRNA /GEN=KIAA0171 /PROD=KIAA0171 gene product /DB_XREF=gi:7661967 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1 NM_014666 clathrin interactor 1 CLINT1 9685 NM_001195555 /// NM_001195556 /// NM_014666 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction 201770_at NM_004596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004596.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. /FEA=mRNA /GEN=SNRPA /PROD=small nuclear ribonucleoprotein polypeptide A /DB_XREF=gi:4759155 /UG=Hs.173255 small nuclear ribonucleoprotein polypeptide A /FL=gb:BC000405.1 gb:NM_004596.1 NM_004596 small nuclear ribonucleoprotein polypeptide A SNRPA 6626 NM_004596 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201771_at NM_005698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005698.1 /DEF=Homo sapiens secretory carrier membrane protein 3 (SCAMP3), mRNA. /FEA=mRNA /GEN=SCAMP3 /PROD=secretory carrier membrane protein 3 /DB_XREF=gi:5032076 /UG=Hs.200600 secretory carrier membrane protein 3 /FL=gb:BC000161.2 gb:BC005135.1 gb:AF005039.1 gb:NM_005698.1 NM_005698 secretory carrier membrane protein 3 SCAMP3 10067 NM_005698 /// NM_052837 /// XM_006711105 /// XM_006711106 /// XM_006711107 /// XM_006726206 /// XM_006726207 /// XM_006726208 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201772_at NM_015878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015878.1 /DEF=Homo sapiens antizyme inhibitor (LOC51582), mRNA. /FEA=mRNA /GEN=LOC51582 /PROD=antizyme inhibitor /DB_XREF=gi:7706219 /UG=Hs.223014 antizyme inhibitor /FL=gb:D88674.1 gb:NM_015878.1 NM_015878 antizyme inhibitor 1 AZIN1 51582 NM_015878 /// NM_148174 /// XM_005250969 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0042978 // ornithine decarboxylase activator activity // inferred from electronic annotation 201773_at NM_015339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015339.1 /DEF=Homo sapiens activity-dependent neuroprotective protein (ADNP), mRNA. /FEA=mRNA /GEN=ADNP /PROD=activity-dependent neuroprotective protein /DB_XREF=gi:12229216 /UG=Hs.3657 activity-dependent neuroprotective protein /FL=gb:AF250860.1 gb:NM_015339.1 NM_015339 activity-dependent neuroprotector homeobox ADNP 23394 NM_001282531 /// NM_001282532 /// NM_015339 /// NM_181442 /// XM_006723759 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201774_s_at AK022511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022511.1 /DEF=Homo sapiens cDNA FLJ12449 fis, clone NT2RM1000314, highly similar to Human mRNA for KIAA0159 gene. /FEA=mRNA /DB_XREF=gi:10433940 /UG=Hs.5719 chromosome condensation-related SMC-associated protein 1 /FL=gb:NM_014865.1 gb:D63880.1 AK022511 non-SMC condensin I complex, subunit D2 NCAPD2 9918 NM_014865 0000278 // mitotic cell cycle // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0000797 // condensin core heterodimer // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042393 // histone binding // non-traceable author statement 201775_s_at AA676790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA676790 /FEA=EST /DB_XREF=gi:2657312 /DB_XREF=est:zj64h12.s1 /CLONE=IMAGE:455111 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 AA676790 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201776_s_at AK001487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001487.1 /DEF=Homo sapiens cDNA FLJ10625 fis, clone NT2RP2005540, highly similar to Homo sapiens mRNA for KIAA0494 protein. /FEA=mRNA /DB_XREF=gi:7022773 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 AK001487 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201777_s_at BC002525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002525.1 /DEF=Homo sapiens, KIAA0494 gene product, clone MGC:1949, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0494 gene product /DB_XREF=gi:12803404 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 BC002525 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201778_s_at NM_014774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014774.1 /DEF=Homo sapiens KIAA0494 gene product (KIAA0494), mRNA. /FEA=mRNA /GEN=KIAA0494 /PROD=KIAA0494 gene product /DB_XREF=gi:7662159 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 NM_014774 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201779_s_at AF070558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070558.1 /DEF=Homo sapiens clone 24450 RING zinc finger protein RZF mRNA, complete cds. /FEA=mRNA /PROD=RING zinc finger protein RZF /DB_XREF=gi:3387924 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1 AF070558 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183382 /// NM_183383 /// NM_183384 /// XM_005247092 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201780_s_at NM_007282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007282.1 /DEF=Homo sapiens ring finger protein 13 (RNF13), mRNA. /FEA=mRNA /GEN=RNF13 /PROD=ring finger protein 13 /DB_XREF=gi:6005863 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1 NM_007282 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183382 /// NM_183383 /// NM_183384 /// XM_005247092 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201781_s_at AL558532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL558532 /FEA=EST /DB_XREF=gi:12903142 /DB_XREF=est:AL558532 /CLONE=CS0DJ006YJ15 (5 prime) /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1 AL558532 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // inferred from direct assay /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036004 // GAF domain binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 201782_s_at NM_003977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003977.1 /DEF=Homo sapiens aryl hydrocarbon receptor-interacting protein (AIP), mRNA. /FEA=mRNA /GEN=AIP /PROD=aryl hydrocarbon receptor-interacting protein /DB_XREF=gi:4502008 /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1 NM_003977 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // inferred from direct assay /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036004 // GAF domain binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 201783_s_at NM_021975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021975.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) (RELA), mRNA. /FEA=mRNA /GEN=RELA /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog A (nuclear factor of kappa light polypeptide geneenhancer in B-cells 3 (p65)) /DB_XREF=gi:11496238 /UG=Hs.75569 v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) /FL=gb:NM_021975.1 gb:L19067.1 NM_021975 v-rel avian reticuloendotheliosis viral oncogene homolog A RELA 5970 NM_001145138 /// NM_001243984 /// NM_001243985 /// NM_021975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006117 // acetaldehyde metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0006968 // cellular defense response // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from direct assay /// 0014040 // positive regulation of Schwann cell differentiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051607 // defense response to virus // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071354 // cellular response to interleukin-6 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from mutant phenotype /// 2000630 // positive regulation of miRNA metabolic process // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0071532 // ankyrin repeat binding // inferred from electronic annotation 201784_s_at NM_014267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014267.1 /DEF=Homo sapiens small acidic protein (IMAGE145052), mRNA. /FEA=mRNA /GEN=IMAGE145052 /PROD=small acidic protein /DB_XREF=gi:7657233 /UG=Hs.78050 small acidic protein /FL=gb:U51678.1 gb:NM_014267.1 NM_014267 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 201785_at NM_002933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002933.1 /DEF=Homo sapiens ribonuclease, RNase A family, 1 (pancreatic) (RNASE1), mRNA. /FEA=mRNA /GEN=RNASE1 /PROD=ribonuclease, RNase A family, 1 (pancreatic) /DB_XREF=gi:4506546 /UG=Hs.78224 ribonuclease, RNase A family, 1 (pancreatic) /FL=gb:BC005324.1 gb:NM_002933.1 gb:D26129.1 NM_002933 ribonuclease, RNase A family, 1 (pancreatic) RNASE1 6035 NM_002933 /// NM_198232 /// NM_198234 /// NM_198235 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation 201786_s_at NM_001111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001111.2 /DEF=Homo sapiens adenosine deaminase, RNA-specific (ADAR), transcript variant ADAR-a, mRNA. /FEA=mRNA /GEN=ADAR /PROD=adenosine deaminase, RNA-specific, isoformADAR-a /DB_XREF=gi:7669471 /UG=Hs.7957 adenosine deaminase, RNA-specific /FL=gb:U10439.1 gb:NM_001111.2 gb:U18121.1 NM_001111 adenosine deaminase, RNA-specific ADAR 103 NM_001025107 /// NM_001111 /// NM_001193495 /// NM_015840 /// NM_015841 /// XM_006711109 /// XM_006711110 /// XM_006711111 /// XM_006711112 /// XM_006711113 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // inferred from mutant phenotype /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred from direct assay /// 0016556 // mRNA modification // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0044530 // supraspliceosomal complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // non-traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201787_at NM_001996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001996.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant C, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform C precursor /DB_XREF=gi:4503662 /UG=Hs.79732 fibulin 1 /FL=gb:NM_001996.1 NM_001996 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 201788_at NM_007372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007372.1 /DEF=Homo sapiens RNA helicase-related protein (RNAHP), mRNA. /FEA=mRNA /GEN=RNAHP /PROD=RNA helicase-related protein /DB_XREF=gi:11321631 /UG=Hs.8765 RNA helicase-related protein /FL=gb:NM_007372.1 gb:AF083255.1 NM_007372 DEAD (Asp-Glu-Ala-Asp) box helicase 42 DDX42 11325 NM_007372 /// NM_203499 /// XM_006721657 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008104 // protein localization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201789_at BC000637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000637.1 /DEF=Homo sapiens, CGI-86 protein, clone MGC:681, mRNA, complete cds. /FEA=mRNA /PROD=CGI-86 protein /DB_XREF=gi:12653704 /UG=Hs.109201 CGI-86 protein /FL=gb:BC000637.1 gb:AF151844.1 gb:NM_016029.1 BC000637 pecanex-like 4 (Drosophila) PCNXL4 64430 NM_022495 /// XM_005268009 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201790_s_at AW150953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW150953 /FEA=EST /DB_XREF=gi:6198851 /DB_XREF=est:xg42f09.x1 /CLONE=IMAGE:2630249 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1 AW150953 7-dehydrocholesterol reductase DHCR7 1717 NM_001163817 /// NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay 201791_s_at NM_001360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001360.1 /DEF=Homo sapiens 7-dehydrocholesterol reductase (DHCR7), mRNA. /FEA=mRNA /GEN=DHCR7 /PROD=7-dehydrocholesterol reductase /DB_XREF=gi:4503320 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1 NM_001360 7-dehydrocholesterol reductase DHCR7 1717 NM_001163817 /// NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay 201792_at NM_001129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001129.2 /DEF=Homo sapiens AE-binding protein 1 (AEBP1), mRNA. /FEA=mRNA /GEN=AEBP1 /PROD=adipocyte enhancer binding protein 1 precursor /DB_XREF=gi:4755145 /UG=Hs.118397 AE-binding protein 1 /FL=gb:D86479.1 gb:AF053944.1 gb:NM_001129.2 NM_001129 AE binding protein 1 AEBP1 165 NM_001129 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 201793_x_at BF509099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF509099 /FEA=EST /DB_XREF=gi:11592397 /DB_XREF=est:UI-H-BI4-aou-e-05-0-UI.s1 /CLONE=IMAGE:3086288 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1 BF509099 SMG7 nonsense mediated mRNA decay factor SMG7 9887 NM_001174061 /// NM_014837 /// NM_173156 /// NM_201568 /// NM_201569 /// XM_005245647 /// XM_005245648 /// XM_005245649 /// XM_005245652 /// XM_005245653 /// XM_005245654 /// XM_005245655 /// XM_005245656 /// XM_006711674 /// XM_006711675 /// XM_006711676 /// XM_006711677 /// XM_006711678 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201794_s_at NM_014837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014837.1 /DEF=Homo sapiens KIAA0250 gene product (KIAA0250), mRNA. /FEA=mRNA /GEN=KIAA0250 /PROD=KIAA0250 gene product /DB_XREF=gi:7662023 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1 NM_014837 SMG7 nonsense mediated mRNA decay factor SMG7 9887 NM_001174061 /// NM_014837 /// NM_173156 /// NM_201568 /// NM_201569 /// XM_005245647 /// XM_005245648 /// XM_005245649 /// XM_005245652 /// XM_005245653 /// XM_005245654 /// XM_005245655 /// XM_005245656 /// XM_006711674 /// XM_006711675 /// XM_006711676 /// XM_006711677 /// XM_006711678 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201795_at NM_002296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002296.1 /DEF=Homo sapiens lamin B receptor (LBR), mRNA. /FEA=mRNA /GEN=LBR /PROD=lamin B receptor /DB_XREF=gi:4504960 /UG=Hs.152931 lamin B receptor /FL=gb:L25931.1 gb:NM_002296.1 NM_002296 lamin B receptor LBR 3930 NM_002296 /// NM_194442 /// XM_005273125 0006695 // cholesterol biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070087 // chromo shadow domain binding // inferred from physical interaction 201796_s_at BE790854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE790854 /FEA=EST /DB_XREF=gi:10212052 /DB_XREF=est:601582271F1 /CLONE=IMAGE:3936952 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1 BE790854 valyl-tRNA synthetase VARS 7407 NM_006295 /// XM_005249362 /// XM_005272869 /// XM_005274886 /// XM_005275021 /// XM_005275290 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201797_s_at NM_006295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006295.1 /DEF=Homo sapiens valyl-tRNA synthetase 2 (VARS2), mRNA. /FEA=mRNA /GEN=VARS2 /PROD=valyl-tRNA synthetase 2 /DB_XREF=gi:5454157 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1 NM_006295 valyl-tRNA synthetase VARS 7407 NM_006295 /// XM_005249362 /// XM_005272869 /// XM_005274886 /// XM_005275021 /// XM_005275290 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201798_s_at NM_013451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013451.1 /DEF=Homo sapiens fer-1 (C.elegans)-like 3 (myoferlin) (FER1L3), mRNA. /FEA=mRNA /GEN=FER1L3 /PROD=fer-1 (C.elegans)-like 3 (myoferlin) /DB_XREF=gi:7305052 /UG=Hs.234680 fer-1 (C.elegans)-like 3 (myoferlin) /FL=gb:AF182316.1 gb:NM_013451.1 NM_013451 myoferlin MYOF 26509 NM_013451 /// NM_133337 /// XM_005269693 /// XM_005269694 /// XM_006717760 0001778 // plasma membrane repair // inferred from sequence or structural similarity /// 0006936 // muscle contraction // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from sequence or structural similarity 201799_s_at AI927993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927993 /FEA=EST /DB_XREF=gi:5663957 /DB_XREF=est:wo92c11.x1 /CLONE=IMAGE:2462804 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1 AI927993 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008142 // oxysterol binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 201800_s_at AF185696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF185696.1 /DEF=Homo sapiens oxysterol-binding protein 1 (OSBP1) mRNA, complete cds. /FEA=mRNA /GEN=OSBP1 /PROD=oxysterol-binding protein 1 /DB_XREF=gi:10441379 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1 AF185696 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008142 // oxysterol binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 201801_s_at AF079117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF079117.1 /DEF=Homo sapiens equilibrative NBMPR-sensitive nucleoside transporter (ENT1) mRNA, complete cds. /FEA=mRNA /GEN=ENT1 /PROD=equilibrative NBMPR-sensitive nucleosidetransporter /DB_XREF=gi:3694939 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1 AF079117 solute carrier family 29 (equilibrative nucleoside transporter), member 1 SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 /// XM_005248875 /// XM_005248876 /// XM_005248878 /// XM_005248879 /// XM_005248880 /// XM_005248881 /// XM_005248882 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0015858 // nucleoside transport // inferred from direct assay /// 0015862 // uridine transport // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 201802_at NM_004955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004955.1 /DEF=Homo sapiens solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1), mRNA. /FEA=mRNA /GEN=SLC29A1 /PROD=solute carrier family 29 (nucleosidetransporters), member 1 /DB_XREF=gi:4826715 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1 NM_004955 solute carrier family 29 (equilibrative nucleoside transporter), member 1 SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 /// XM_005248875 /// XM_005248876 /// XM_005248878 /// XM_005248879 /// XM_005248880 /// XM_005248881 /// XM_005248882 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0015858 // nucleoside transport // inferred from direct assay /// 0015862 // uridine transport // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 201803_at NM_000938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000938.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide B (140kD) (POLR2B), mRNA. /FEA=mRNA /GEN=POLR2B /PROD=polymerase (RNA) II (DNA directed) polypeptide B(140kD) /DB_XREF=gi:4505940 /UG=Hs.296014 polymerase (RNA) II (DNA directed) polypeptide B (140kD) /FL=gb:NM_000938.1 NM_000938 polymerase (RNA) II (DNA directed) polypeptide B, 140kDa POLR2B 5431 NM_000938 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032549 // ribonucleoside binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201804_x_at NM_001281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001281.1 /DEF=Homo sapiens cytoskeleton-associated protein 1 (CKAP1), mRNA. /FEA=mRNA /GEN=CKAP1 /PROD=CKAP1 /DB_XREF=gi:4502848 /UG=Hs.31053 cytoskeleton-associated protein 1 /FL=gb:AF013488.1 gb:NM_001281.1 gb:D49738.1 NM_001281 tubulin folding cofactor B TBCB 1155 NM_001281 /// XM_006722998 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement 0005515 // protein binding // inferred from physical interaction 201805_at NM_002733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002733.1 /DEF=Homo sapiens protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), mRNA. /FEA=mRNA /GEN=PRKAG1 /PROD=protein kinase, AMP-activated, gamma 1non-catalytic subunit /DB_XREF=gi:4506060 /UG=Hs.3136 protein kinase, AMP-activated, gamma 1 non-catalytic subunit /FL=gb:BC000358.1 gb:U42412.1 gb:NM_002733.1 NM_002733 protein kinase, AMP-activated, gamma 1 non-catalytic subunit PRKAG1 5571 NM_001206709 /// NM_001206710 /// NM_002733 /// NM_212461 /// XM_005269019 /// XM_005269020 /// XM_006719499 /// XM_006719500 0006110 // regulation of glycolytic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031588 // AMP-activated protein kinase complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004679 // AMP-activated protein kinase activity // inferred from sequence or structural similarity /// 0004691 // cAMP-dependent protein kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016208 // AMP binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity 201806_s_at NM_007245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007245.1 /DEF=Homo sapiens ataxin 2 related protein (A2LP), transcript variant 1, mRNA. /FEA=mRNA /GEN=A2LP /PROD=ataxin 2 related protein, isoform 1 /DB_XREF=gi:6005698 /UG=Hs.43509 ataxin 2 related protein /FL=gb:AF034373.1 gb:NM_007245.1 NM_007245 ataxin 2-like ATXN2L 11273 NM_007245 /// NM_017492 /// NM_145714 /// NM_148414 /// NM_148415 /// NM_148416 /// XM_005255061 /// XM_005255062 /// XM_005255063 /// XM_005255064 /// XM_005255065 /// XM_005255066 /// XM_005255067 /// XM_005255068 /// XM_005255069 /// XM_005255070 /// XM_005255071 /// XM_005255072 /// XM_005255074 /// XM_005255075 /// XM_005255076 /// XM_005255077 /// XM_006721007 /// XM_006721008 /// XM_006721009 /// XM_006721010 /// XM_006721011 /// XM_006721012 /// XM_006721013 /// XR_243256 0010603 // regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0034063 // stress granule assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201807_at NM_004896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004896.1 /DEF=Homo sapiens vacuolar protein sorting 26 (yeast homolog) (VPS26), mRNA. /FEA=mRNA /GEN=VPS26 /PROD=vacuolar protein sorting 26 (yeast homolog) /DB_XREF=gi:4758509 /UG=Hs.67052 vacuolar protein sorting 26 (yeast homolog) /FL=gb:AF054179.1 gb:NM_004896.1 gb:AF175266.1 NM_004896 vacuolar protein sorting 26 homolog A (S. pombe) VPS26A 9559 NM_001035260 /// NM_004896 0006810 // transport // inferred from electronic annotation /// 0007034 // vacuolar transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // non-traceable author statement 201808_s_at BE732652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE732652 /FEA=EST /DB_XREF=gi:10146644 /DB_XREF=est:601571266F1 /CLONE=IMAGE:3925601 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1 BE732652 endoglin ENG 2022 NM_000118 /// NM_001114753 /// NM_001278138 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001300 // chronological cell aging // inferred from electronic annotation /// 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0003273 // cell migration involved in endocardial cushion formation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0030155 // regulation of cell adhesion // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036273 // response to statin // inferred from electronic annotation /// 0042060 // wound healing // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042325 // regulation of phosphorylation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070483 // detection of hypoxia // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator /// 0072563 // endothelial microparticle // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005072 // transforming growth factor beta receptor, cytoplasmic mediator activity // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 201809_s_at NM_000118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000118.1 /DEF=Homo sapiens endoglin (Osler-Rendu-Weber syndrome 1) (ENG), mRNA. /FEA=mRNA /GEN=ENG /PROD=endoglin precursor /DB_XREF=gi:4557554 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1 NM_000118 endoglin ENG 2022 NM_000118 /// NM_001114753 /// NM_001278138 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001300 // chronological cell aging // inferred from electronic annotation /// 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0003273 // cell migration involved in endocardial cushion formation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0030155 // regulation of cell adhesion // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036273 // response to statin // inferred from electronic annotation /// 0042060 // wound healing // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042325 // regulation of phosphorylation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070483 // detection of hypoxia // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator /// 0072563 // endothelial microparticle // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005072 // transforming growth factor beta receptor, cytoplasmic mediator activity // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 201810_s_at AL562152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL562152 /FEA=EST /DB_XREF=gi:12910291 /DB_XREF=est:AL562152 /CLONE=CS0DC001YK23 (3 prime) /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1 AL562152 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 /// XM_006713420 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201811_x_at NM_004844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004844.1 /DEF=Homo sapiens SH3-domain binding protein 5 (BTK-associated) (SH3BP5), mRNA. /FEA=mRNA /GEN=SH3BP5 /PROD=SH3-domain binding protein 5 (BTK-associated) /DB_XREF=gi:4759057 /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1 NM_004844 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 /// XM_006713420 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201812_s_at NM_019059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019059.1 /DEF=Homo sapiens 6.2 kd protein (LOC54543), mRNA. /FEA=mRNA /GEN=LOC54543 /PROD=6.2 kd protein /DB_XREF=gi:9506858 /UG=Hs.112318 6.2 kd protein /FL=gb:BC001732.1 gb:AF150733.1 gb:NM_019059.1 NM_019059 chromosome 4 open reading frame 46 /// translocase of outer mitochondrial membrane 7 homolog (yeast) C4orf46 /// TOMM7 54543 /// 201725 NM_001008393 /// NM_019059 /// NR_077234 /// NR_077235 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030150 // protein import into mitochondrial matrix // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201813_s_at AI654161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI654161 /FEA=EST /DB_XREF=gi:4738140 /DB_XREF=est:ty62e04.x1 /CLONE=IMAGE:2283678 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI654161 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201814_at AI300084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI300084 /FEA=EST /DB_XREF=gi:3959430 /DB_XREF=est:qn59f02.x1 /CLONE=IMAGE:1902555 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI300084 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201815_s_at NM_014744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014744.1 /DEF=Homo sapiens KIAA0210 gene product (KIAA0210), mRNA. /FEA=mRNA /GEN=KIAA0210 /PROD=KIAA0210 gene product /DB_XREF=gi:7661997 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 NM_014744 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201816_s_at NM_001483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001483.1 /DEF=Homo sapiens glioblastoma amplified sequence (GBAS), mRNA. /FEA=mRNA /GEN=GBAS /PROD=glioblastoma amplified sequence /DB_XREF=gi:4503936 /UG=Hs.152707 glioblastoma amplified sequence /FL=gb:BC000732.1 gb:BC001837.1 gb:AF029786.1 gb:NM_001483.1 NM_001483 glioblastoma amplified sequence GBAS 2631 NM_001202469 /// NM_001483 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 2000984 // negative regulation of ATP citrate synthase activity // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 201817_at NM_014671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014671.1 /DEF=Homo sapiens KIAA0010 gene product (KIAA0010), mRNA. /FEA=mRNA /GEN=KIAA0010 /PROD=KIAA0010 gene product /DB_XREF=gi:7661855 /UG=Hs.155287 KIAA0010 gene product /FL=gb:D13635.1 gb:NM_014671.1 NM_014671 ubiquitin protein ligase E3C UBE3C 9690 NM_014671 /// XM_005249564 /// XM_005249565 0000209 // protein polyubiquitination // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0000502 // proteasome complex // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 201818_at NM_024830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024830.1 /DEF=Homo sapiens hypothetical protein FLJ12443 (FLJ12443), mRNA. /FEA=mRNA /GEN=FLJ12443 /PROD=hypothetical protein FLJ12443 /DB_XREF=gi:13376233 /UG=Hs.179882 hypothetical protein FLJ12443 /FL=gb:NM_024830.1 NM_024830 lysophosphatidylcholine acyltransferase 1 LPCAT1 79888 NM_024830 /// XM_005248373 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 2001246 // negative regulation of phosphatidylcholine biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047159 // 1-alkenylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from direct assay /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from sequence or structural similarity /// 0047191 // 1-alkylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047192 // 1-alkylglycerophosphocholine O-acetyltransferase activity // inferred from electronic annotation 201819_at NM_005505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005505.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 (CD36L1), mRNA. /FEA=mRNA /GEN=CD36L1 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 1 /DB_XREF=gi:5031628 /UG=Hs.180616 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 /FL=gb:NM_005505.1 NM_005505 scavenger receptor class B, member 1 SCARB1 949 NM_001082959 /// NM_005505 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0044406 // adhesion of symbiont to host // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001786 // phosphatidylserine binding // inferred from sequence or structural similarity /// 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0070506 // high-density lipoprotein particle receptor activity // inferred from direct assay 201820_at NM_000424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000424.1 /DEF=Homo sapiens keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) (KRT5), mRNA. /FEA=mRNA /GEN=KRT5 /PROD=keratin 5 (epidermolysis bullosa simplex,Dowling-MearaKobnerWeber-Cockayne types) /DB_XREF=gi:4557889 /UG=Hs.195850 keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) /FL=gb:M21389.1 gb:NM_000424.1 NM_000424 keratin 5 KRT5 3852 NM_000424 0008544 // epidermis development // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 201821_s_at BC004439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004439.1 /DEF=Homo sapiens, translocase of inner mitochondrial membrane 17 (yeast) homolog A, clone MGC:4031, mRNA, complete cds. /FEA=mRNA /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:13325239 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1 BC004439 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201822_at NM_006335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006335.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 17 (yeast) homolog A (TIM17), mRNA. /FEA=mRNA /GEN=TIM17 /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:5454119 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1 NM_006335 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201823_s_at NM_004290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004290.1 /DEF=Homo sapiens ring finger protein 14 (RNF14), mRNA. /FEA=mRNA /GEN=RNF14 /PROD=ring finger protein 14 /DB_XREF=gi:4757761 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1 NM_004290 ring finger protein 14 RNF14 9604 NM_001201365 /// NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 /// XM_005268536 /// XM_005268537 /// XM_005268538 /// XM_005268539 /// XM_005268540 /// XM_005268541 /// XM_005268542 /// XM_005268543 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 201824_at AB022663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB022663.1 /DEF=Homo sapiens HFB30 mRNA, complete cds. /FEA=mRNA /GEN=HFB30 /DB_XREF=gi:5019617 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1 AB022663 ring finger protein 14 RNF14 9604 NM_001201365 /// NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 /// XM_005268536 /// XM_005268537 /// XM_005268538 /// XM_005268539 /// XM_005268540 /// XM_005268541 /// XM_005268542 /// XM_005268543 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 201825_s_at AL572542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL572542 /FEA=EST /DB_XREF=gi:12930912 /DB_XREF=est:AL572542 /CLONE=CS0DI008YC09 (3 prime) /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1 AL572542 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 201826_s_at NM_016002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016002.1 /DEF=Homo sapiens CGI-49 protein (LOC51097), mRNA. /FEA=mRNA /GEN=LOC51097 /PROD=CGI-49 protein /DB_XREF=gi:7705766 /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1 NM_016002 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 201827_at AF113019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113019.1 /DEF=Homo sapiens PRO2451 mRNA, complete cds. /FEA=mRNA /PROD=PRO2451 /DB_XREF=gi:6642761 /UG=Hs.250581 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 /FL=gb:U66618.1 gb:NM_003077.1 gb:AF113019.1 AF113019 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 SMARCD2 6603 NM_001098426 /// NM_003077 /// XM_005257604 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201828_x_at NM_003928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003928.1 /DEF=Homo sapiens CAAX box 1 (CXX1), mRNA. /FEA=mRNA /GEN=CXX1 /PROD=CAAX box 1 /DB_XREF=gi:4503180 /UG=Hs.250708 CAAX box 1 /FL=gb:BC002385.1 gb:BC002410.1 gb:AF038168.1 gb:AF052096.1 gb:NM_003928.1 NM_003928 family with sequence similarity 127, member A FAM127A 8933 NM_001078171 /// NM_003928 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201829_at AW263232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW263232 /FEA=EST /DB_XREF=gi:6640048 /DB_XREF=est:xn79e03.x1 /CLONE=IMAGE:2700700 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1 AW263232 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 /// NR_073040 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 201830_s_at NM_005863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005863.1 /DEF=Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA. /FEA=mRNA /GEN=NET1 /PROD=neuroepithelial cell transforming gene 1 /DB_XREF=gi:5031938 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1 NM_005863 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 /// NR_073040 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 201831_s_at BE875592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE875592 /FEA=EST /DB_XREF=gi:10324368 /DB_XREF=est:601487031F1 /CLONE=IMAGE:3889710 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1 BE875592 USO1 vesicle transport factor USO1 8615 NM_001290049 /// NM_003715 /// XM_006714395 /// XM_006714396 /// XM_006714397 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045056 // transcytosis // not recorded /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048211 // Golgi vesicle docking // not recorded /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061025 // membrane fusion // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 201832_s_at NM_003715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003715.1 /DEF=Homo sapiens vesicle docking protein p115 (P115), mRNA. /FEA=mRNA /GEN=P115 /PROD=vesicle docking protein p115 /DB_XREF=gi:4505540 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1 NM_003715 USO1 vesicle transport factor USO1 8615 NM_001290049 /// NM_003715 /// XM_006714395 /// XM_006714396 /// XM_006714397 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045056 // transcytosis // not recorded /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048211 // Golgi vesicle docking // not recorded /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061025 // membrane fusion // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 201833_at NM_001527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001527.1 /DEF=Homo sapiens histone deacetylase 2 (HDAC2), mRNA. /FEA=mRNA /GEN=HDAC2 /PROD=histone deacetylase 2 /DB_XREF=gi:4557640 /UG=Hs.3352 histone deacetylase 2 /FL=gb:U31814.1 gb:NM_001527.1 NM_001527 histone deacetylase 2 HDAC2 3066 NM_001527 /// NR_033441 /// NR_073443 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred by curator /// 0006344 // maintenance of chromatin silencing // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009913 // epidermal cell differentiation // inferred from sequence or structural similarity /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred by curator /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred by curator /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061198 // fungiform papilla formation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0070933 // histone H4 deacetylation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090311 // regulation of protein deacetylation // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from mutant phenotype /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 201834_at BC001007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001007.1 /DEF=Homo sapiens, protein kinase, AMP-activated, beta 1 non-catalytic subunit, clone MGC:8608, mRNA, complete cds. /FEA=mRNA /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:12654368 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1 BC001007 protein kinase, AMP-activated, beta 1 non-catalytic subunit PRKAB1 5564 NM_006253 /// XM_005253909 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 201835_s_at NM_006253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006253.1 /DEF=Homo sapiens protein kinase, AMP-activated, beta 1 non-catalytic subunit (PRKAB1), mRNA. /FEA=mRNA /GEN=PRKAB1 /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:5453967 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1 NM_006253 protein kinase, AMP-activated, beta 1 non-catalytic subunit PRKAB1 5564 NM_006253 /// XM_005253909 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 201836_s_at AU154740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154740 /FEA=EST /DB_XREF=gi:11016261 /DB_XREF=est:AU154740 /CLONE=NT2RP4001989 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 AU154740 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201837_s_at AF197954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF197954.1 /DEF=Homo sapiens adenocarcinoma antigen ART1 mRNA, complete cds. /FEA=mRNA /PROD=adenocarcinoma antigen ART1 /DB_XREF=gi:11066257 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 AF197954 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201838_s_at NM_014860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014860.1 /DEF=Homo sapiens KIAA0764 gene product (KIAA0764), mRNA. /FEA=mRNA /GEN=KIAA0764 /PROD=KIAA0764 gene product /DB_XREF=gi:7662291 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 NM_014860 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201839_s_at NM_002354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002354.1 /DEF=Homo sapiens tumor-associated calcium signal transducer 1 (TACSTD1), mRNA. /FEA=mRNA /GEN=TACSTD1 /PROD=tumor-associated calcium signal transducer 1precursor /DB_XREF=gi:4505058 /UG=Hs.692 tumor-associated calcium signal transducer 1 /FL=gb:M32306.1 gb:M33011.1 gb:NM_002354.1 NM_002354 epithelial cell adhesion molecule EPCAM 4072 NM_002354 0001657 // ureteric bud development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from mutant phenotype /// 2000048 // negative regulation of cell-cell adhesion mediated by cadherin // inferred from direct assay /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay 201840_at NM_006156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006156.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 8 (NEDD8), mRNA. /FEA=mRNA /GEN=NEDD8 /PROD=neural precursor cell expressed, developmentallydown-regulated 8 /DB_XREF=gi:5453759 /UG=Hs.75512 neural precursor cell expressed, developmentally down-regulated 8 /FL=gb:D23662.1 gb:NM_006156.1 NM_006156 neural precursor cell expressed, developmentally down-regulated 8 NEDD8 4738 NM_006156 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0045116 // protein neddylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201841_s_at NM_001540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001540.2 /DEF=Homo sapiens heat shock 27kD protein 1 (HSPB1), mRNA. /FEA=mRNA /GEN=HSPB1 /PROD=heat shock 27kD protein 1 /DB_XREF=gi:4996892 /UG=Hs.76067 heat shock 27kD protein 1 /FL=gb:AB020027.1 gb:BC000510.1 gb:U90906.1 gb:NM_001540.2 NM_001540 heat shock 27kDa protein 1 HSPB1 3315 NM_001540 0001895 // retina homeostasis // inferred from expression pattern /// 0006446 // regulation of translational initiation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0032731 // positive regulation of interleukin-1 beta production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000502 // proteasome complex // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201842_s_at AI826799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI826799 /FEA=EST /DB_XREF=gi:5447470 /DB_XREF=est:wk56d07.x1 /CLONE=IMAGE:2419405 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2 AI826799 EGF containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 201843_s_at NM_004105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004105.2 /DEF=Homo sapiens EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1, mRNA. /FEA=mRNA /GEN=EFEMP1 /PROD=EGF-containing fibulin-like extracellular matrixprotein 1 precursor, isoform a precursor /DB_XREF=gi:9665261 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2 NM_004105 EGF containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 201844_s_at W84482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W84482 /FEA=EST /DB_XREF=gi:1395613 /DB_XREF=est:zd89h07.s1 /CLONE=IMAGE:356701 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 W84482 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201845_s_at AB029551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB029551.1 /DEF=Homo sapiens YEAF1 mRNA for YY1 and E4TF1 associated factor 1, complete cds. /FEA=mRNA /GEN=YEAF1 /PROD=YY1 and E4TF1 associated factor 1 /DB_XREF=gi:6714542 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 AB029551 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201846_s_at NM_012234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012234.1 /DEF=Homo sapiens RING1 and YY1 binding protein (RYBP), mRNA. /FEA=mRNA /GEN=RYBP /PROD=RING1 and YY1 binding protein /DB_XREF=gi:6912639 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 NM_012234 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201847_at NM_000235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000235.1 /DEF=Homo sapiens lipase A, lysosomal acid, cholesterol esterase (Wolman disease) (LIPA), mRNA. /FEA=mRNA /GEN=LIPA /PROD=lipase A precursor /DB_XREF=gi:4557720 /UG=Hs.85226 lipase A, lysosomal acid, cholesterol esterase (Wolman disease) /FL=gb:M74775.1 gb:NM_000235.1 gb:U08464.1 NM_000235 lipase A, lysosomal acid, cholesterol esterase LIPA 3988 NM_000235 /// NM_001127605 /// NM_001288979 /// NR_110233 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004771 // sterol esterase activity // inferred from direct assay /// 0016298 // lipase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 201848_s_at U15174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U15174.1 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3) mRNA, complete cds. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:558845 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2 U15174 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006915 // apoptotic process // inferred from physical interaction /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010637 // negative regulation of mitochondrial fusion // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043243 // positive regulation of protein complex disassembly // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071279 // cellular response to cobalt ion // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097345 // mitochondrial outer membrane permeabilization // inferred from direct assay /// 1990144 // intrinsic apoptotic signaling pathway in response to hypoxia // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 201849_at NM_004052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004052.2 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:7669480 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2 NM_004052 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006915 // apoptotic process // inferred from physical interaction /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010637 // negative regulation of mitochondrial fusion // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043243 // positive regulation of protein complex disassembly // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071279 // cellular response to cobalt ion // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097345 // mitochondrial outer membrane permeabilization // inferred from direct assay /// 1990144 // intrinsic apoptotic signaling pathway in response to hypoxia // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 201850_at NM_001747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001747.1 /DEF=Homo sapiens capping protein (actin filament), gelsolin-like (CAPG), mRNA. /FEA=mRNA /GEN=CAPG /PROD=capping protein (actin filament), gelsolin-like /DB_XREF=gi:4502560 /UG=Hs.82422 capping protein (actin filament), gelsolin-like /FL=gb:BC000728.1 gb:M94345.1 gb:NM_001747.1 NM_001747 capping protein (actin filament), gelsolin-like CAPG 822 NM_001256139 /// NM_001256140 /// NM_001747 /// XM_005264581 /// XM_005264582 0006461 // protein complex assembly // non-traceable author statement /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008290 // F-actin capping protein complex // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201851_at NM_003025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003025.1 /DEF=Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA. /FEA=mRNA /GEN=SH3GL1 /PROD=SH3-domain GRB2-like 1 /DB_XREF=gi:4506928 /UG=Hs.97616 SH3-domain GRB2-like 1 /FL=gb:BC001270.1 gb:U65999.1 gb:NM_003025.1 NM_003025 SH3-domain GRB2-like 1 SH3GL1 6455 NM_001199943 /// NM_001199944 /// NM_003025 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation 201852_x_at AI813758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI813758 /FEA=EST /DB_XREF=gi:5424973 /DB_XREF=est:wk79b04.x1 /CLONE=IMAGE:2421583 /UG=Hs.119571 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) /FL=gb:NM_000090.1 AI813758 collagen, type III, alpha 1 COL3A1 1281 NM_000090 0001501 // skeletal system development // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // non-traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005586 // collagen type III trimer // inferred from mutant phenotype /// 0005586 // collagen type III trimer // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement 0005178 // integrin binding // inferred from mutant phenotype /// 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 201853_s_at NM_021873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021873.1 /DEF=Homo sapiens cell division cycle 25B (CDC25B), transcript variant 3, mRNA. /FEA=mRNA /GEN=CDC25B /PROD=cell division cycle 25B, isoform 3 /DB_XREF=gi:11641412 /UG=Hs.153752 cell division cycle 25B /FL=gb:NM_021873.1 NM_021873 cell division cycle 25B CDC25B 994 NM_001287516 /// NM_001287517 /// NM_001287518 /// NM_001287519 /// NM_001287520 /// NM_001287522 /// NM_001287524 /// NM_004358 /// NM_021872 /// NM_021873 /// NM_021874 /// NM_212530 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 201854_s_at AI744148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744148 /FEA=EST /DB_XREF=gi:5112436 /DB_XREF=est:wc36h01.x1 /CLONE=IMAGE:2317297 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1 AI744148 ATM interactor ATMIN 23300 NM_015251 /// XM_005255866 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201855_s_at NM_015251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015251.1 /DEF=Homo sapiens KIAA0431 protein (KIAA0431), mRNA. /FEA=mRNA /GEN=KIAA0431 /PROD=KIAA0431 protein /DB_XREF=gi:7662115 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1 NM_015251 ATM interactor ATMIN 23300 NM_015251 /// XM_005255866 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201856_s_at BC000376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000376.1 /DEF=Homo sapiens, clone MGC:8379, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:8379) /DB_XREF=gi:12653216 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1 BC000376 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201857_at NM_016107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016107.1 /DEF=Homo sapiens M-phase phosphoprotein homolog (LOC51663), mRNA. /FEA=mRNA /GEN=LOC51663 /PROD=M-phase phosphoprotein homolog /DB_XREF=gi:7706372 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1 NM_016107 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201858_s_at J03223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03223.1 /DEF=Human secretory granule proteoglycan peptide core mRNA, complete cds. /FEA=mRNA /GEN=PRG1 /DB_XREF=gi:190419 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1 J03223 serglycin SRGN 5552 NM_002727 /// NR_036430 0002576 // platelet degranulation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0042588 // zymogen granule // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation 201859_at NM_002727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002727.1 /DEF=Homo sapiens proteoglycan 1, secretory granule (PRG1), mRNA. /FEA=mRNA /GEN=PRG1 /PROD=proteoglycan 1, secretory granule /DB_XREF=gi:4506044 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1 NM_002727 serglycin SRGN 5552 NM_002727 /// NR_036430 0002576 // platelet degranulation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0042588 // zymogen granule // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation 201860_s_at NM_000930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000930.1 /DEF=Homo sapiens plasminogen activator, tissue (PLAT), mRNA. /FEA=mRNA /GEN=PLAT /PROD=plasminogen activator, tissue /DB_XREF=gi:4505860 /UG=Hs.274404 plasminogen activator, tissue /FL=gb:NM_000931.1 gb:M15518.1 gb:M18182.1 gb:NM_000930.1 NM_000930 plasminogen activator, tissue PLAT 5327 NM_000930 /// NM_000931 /// NM_033011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060279 // positive regulation of ovulation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201861_s_at BF965566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF965566 /FEA=EST /DB_XREF=gi:12332781 /DB_XREF=est:602277032F1 /CLONE=IMAGE:4364790 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1 BF965566 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201862_s_at NM_004735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004735.1 /DEF=Homo sapiens leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), mRNA. /FEA=mRNA /GEN=LRRFIP1 /PROD=leucine rich repeat (in FLII) interactingprotein 1 /DB_XREF=gi:4758689 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1 NM_004735 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201863_at NM_014077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014077.1 /DEF=Homo sapiens DKFZP586O0120 protein (DKFZP586O0120), mRNA. /FEA=mRNA /GEN=DKFZP586O0120 /PROD=DKFZP586O0120 protein /DB_XREF=gi:7661695 /UG=Hs.4766 DKFZP586O0120 protein /FL=gb:BC000639.1 gb:AL050157.1 gb:AF151902.1 gb:NM_014077.1 NM_014077 family with sequence similarity 32, member A FAM32A 26017 NM_014077 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201864_at NM_001493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001493.1 /DEF=Homo sapiens GDP dissociation inhibitor 1 (GDI1), mRNA. /FEA=mRNA /GEN=GDI1 /PROD=GDP dissociation inhibitor 1 /DB_XREF=gi:4503970 /UG=Hs.74576 GDP dissociation inhibitor 1 /FL=gb:BC000317.1 gb:NM_001493.1 gb:D45021.1 NM_001493 GDP dissociation inhibitor 1 GDI1 2664 NM_001493 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032482 // Rab protein signal transduction // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0090315 // negative regulation of protein targeting to membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030496 // midbody // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005093 // Rab GDP-dissociation inhibitor activity // inferred from sequence or structural similarity /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation 201865_x_at AI432196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI432196 /FEA=EST /DB_XREF=gi:4308490 /DB_XREF=est:tg77g05.x1 /CLONE=IMAGE:2114840 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1 AI432196 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201866_s_at NM_000176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000176.1 /DEF=Homo sapiens nuclear receptor subfamily 3, group C, member 1 (NR3C1), mRNA. /FEA=mRNA /GEN=NR3C1 /PROD=nuclear receptor subfamily 3, group C, member 1 /DB_XREF=gi:4504132 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1 NM_000176 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201867_s_at AW968555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW968555 /FEA=EST /DB_XREF=gi:8158396 /DB_XREF=est:EST380631 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AW968555 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201868_s_at AI082187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI082187 /FEA=EST /DB_XREF=gi:3418979 /DB_XREF=est:ox75f01.x1 /CLONE=IMAGE:1662169 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AI082187 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201869_s_at BF593932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593932 /FEA=EST /DB_XREF=gi:11686256 /DB_XREF=est:nab48e09.x1 /CLONE=IMAGE:3269104 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 BF593932 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201870_at NM_006809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006809.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 34 (TOM34), mRNA. /FEA=mRNA /GEN=TOM34 /PROD=translocase of outer mitochondrial membrane 34 /DB_XREF=gi:5803204 /UG=Hs.76927 translocase of outer mitochondrial membrane 34 /FL=gb:BC001763.1 gb:U58970.1 gb:NM_006809.1 NM_006809 translocase of outer mitochondrial membrane 34 TOMM34 10953 NM_006809 /// XM_005260254 /// XR_244131 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from physical interaction 201871_s_at NM_015853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015853.1 /DEF=Homo sapiens ORF (LOC51035), mRNA. /FEA=mRNA /GEN=LOC51035 /PROD=unknown protein LOC51035 /DB_XREF=gi:7705653 /UG=Hs.77868 ORF /FL=gb:BC000902.1 gb:M68864.1 gb:NM_015853.1 NM_015853 UBX domain protein 1 UBXN1 51035 NM_001286077 /// NM_001286078 /// NM_015853 /// XM_005274033 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction /// 0071796 // K6-linked polyubiquitin binding // inferred from direct assay 201872_s_at AI002002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI002002 /FEA=EST /DB_XREF=gi:3202473 /DB_XREF=est:ot42e10.s1 /CLONE=IMAGE:1619466 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1 AI002002 ATP-binding cassette, sub-family E (OABP), member 1 ABCE1 6059 NM_001040876 /// NM_002940 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201873_s_at NM_002940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002940.1 /DEF=Homo sapiens ATP-binding cassette, sub-family E (OABP), member 1 (ABCE1), mRNA. /FEA=mRNA /GEN=ABCE1 /PROD=ATP-binding cassette, sub-family E, member 1 /DB_XREF=gi:4506558 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1 NM_002940 ATP-binding cassette, sub-family E (OABP), member 1 ABCE1 6059 NM_001040876 /// NM_002940 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201874_at BF978611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF978611 /FEA=EST /DB_XREF=gi:12345826 /DB_XREF=est:602149061F1 /CLONE=IMAGE:4307822 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1 BF978611 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201875_s_at NM_024569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024569.1 /DEF=Homo sapiens hypothetical protein FLJ21047 (FLJ21047), mRNA. /FEA=mRNA /GEN=FLJ21047 /PROD=hypothetical protein FLJ21047 /DB_XREF=gi:13375739 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1 NM_024569 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201876_at NM_000305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000305.1 /DEF=Homo sapiens paraoxonase 2 (PON2), mRNA. /FEA=mRNA /GEN=PON2 /PROD=paraoxonase 2 /DB_XREF=gi:4505952 /UG=Hs.169857 paraoxonase 2 /FL=gb:L48513.1 gb:AF001601.1 gb:NM_000305.1 NM_000305 paraoxonase 2 PON2 5445 NM_000305 /// NM_001018161 /// XM_005250453 /// XM_005250454 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004064 // arylesterase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201877_s_at NM_002719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002719.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), gamma isoform (PPP2R5C), mRNA. /FEA=mRNA /GEN=PPP2R5C /PROD=protein phosphatase 2, regulatory subunit B(B56), gamma isoform /DB_XREF=gi:4506022 /UG=Hs.171734 protein phosphatase 2, regulatory subunit B (B56), gamma isoform /FL=gb:U37352.1 gb:NM_002719.1 NM_002719 protein phosphatase 2, regulatory subunit B', gamma PPP2R5C 5527 NM_001161725 /// NM_001161726 /// NM_002719 /// NM_178586 /// NM_178587 /// NM_178588 /// XM_005267819 /// XM_005267820 /// XM_005267822 /// XM_005267823 /// XM_005267824 /// XM_005267826 /// XM_005267827 0006508 // proteolysis // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // non-traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // non-traceable author statement 201878_at N25546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25546 /FEA=EST /DB_XREF=gi:1139894 /DB_XREF=est:yx76e05.s1 /CLONE=IMAGE:267680 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2 N25546 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201879_at AI694332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694332 /FEA=EST /DB_XREF=gi:4971672 /DB_XREF=est:wd45e11.x1 /CLONE=IMAGE:2331116 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2 AI694332 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201880_at AL040708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL040708 /FEA=EST /DB_XREF=gi:5409654 /DB_XREF=est:DKFZp434A1015_s1 /CLONE=DKFZp434A1015 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2 AL040708 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201881_s_at NM_005744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005744.2 /DEF=Homo sapiens ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 (ARIH1), mRNA. /FEA=mRNA /GEN=ARIH1 /PROD=ariadne homolog /DB_XREF=gi:9966762 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2 NM_005744 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201882_x_at AI492393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI492393 /FEA=EST /DB_XREF=gi:4393396 /DB_XREF=est:ti27e03.x1 /CLONE=IMAGE:2131708 /UG=Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 /FL=gb:NM_001497.1 gb:D29805.1 AI492393 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction 201883_s_at D29805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D29805.1 /DEF=Human mRNA for beta-1,4-galactosyltransferase, complete cds. /FEA=mRNA /PROD=beta-1,4-galactosyltransferase /DB_XREF=gi:474986 /UG=Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 /FL=gb:NM_001497.1 gb:D29805.1 D29805 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction 201884_at NM_004363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004363.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), mRNA. /FEA=mRNA /GEN=CEACAM5 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 5 /DB_XREF=gi:11386170 /UG=Hs.220529 carcinoembryonic antigen-related cell adhesion molecule 5 /FL=gb:NM_004363.1 gb:M29540.1 NM_004363 carcinoembryonic antigen-related cell adhesion molecule 5 CEACAM5 1048 NM_001291484 /// NM_004363 /// XM_005258413 /// XM_005258415 0010832 // negative regulation of myotube differentiation // inferred from direct assay /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071575 // integral component of external side of plasma membrane // inferred from direct assay 0034235 // GPI anchor binding // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201885_s_at NM_000398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000398.3 /DEF=Homo sapiens diaphorase (NADH) (cytochrome b-5 reductase) (DIA1), nuclear gene encoding mitochondrial protein, transcript variant M, mRNA. /FEA=mRNA /GEN=DIA1 /PROD=cytochrome b5 reductase, membrane-bound isoform /DB_XREF=gi:6552326 /UG=Hs.274464 diaphorase (NADH) (cytochrome b-5 reductase) /FL=gb:BC004821.1 gb:NM_000398.3 NM_000398 cytochrome b5 reductase 3 CYB5R3 1727 NM_000398 /// NM_001129819 /// NM_001171660 /// NM_001171661 /// NM_007326 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0016208 // AMP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 201886_at NM_025230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025230.1 /DEF=Homo sapiens hypthetical protein PRO2389 (PRO2389), mRNA. /FEA=mRNA /GEN=PRO2389 /PROD=hypthetical protein PRO2389 /DB_XREF=gi:13489107 /UG=Hs.283976 hypthetical protein PRO2389 /FL=gb:AF130070.1 gb:AF267858.1 gb:NM_025230.1 NM_025230 DDB1 and CUL4 associated factor 11 DCAF11 80344 NM_001163484 /// NM_025230 /// NM_181357 /// NR_028099 /// NR_028100 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201887_at NM_001560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001560.1 /DEF=Homo sapiens interleukin 13 receptor, alpha 1 (IL13RA1), mRNA. /FEA=mRNA /GEN=IL13RA1 /PROD=interleukin 13 receptor, alpha 1 /DB_XREF=gi:4504646 /UG=Hs.285115 interleukin 13 receptor, alpha 1 /FL=gb:NM_001560.1 gb:U81379.3 NM_001560 interleukin 13 receptor, alpha 1 IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 201888_s_at U81379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U81379.3 /DEF=Homo sapiens interleukin-13 receptor mRNA, complete cds. /FEA=mRNA /PROD=interleukin-13 receptor /DB_XREF=gi:5870850 /UG=Hs.285115 interleukin 13 receptor, alpha 1 /FL=gb:NM_001560.1 gb:U81379.3 U81379 interleukin 13 receptor, alpha 1 IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 201889_at NM_014888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014888.1 /DEF=Homo sapiens predicted osteoblast protein (GS3786), mRNA. /FEA=mRNA /GEN=GS3786 /PROD=predicted osteoblast protein /DB_XREF=gi:7661713 /UG=Hs.29882 predicted osteoblast protein /FL=gb:D87120.1 gb:NM_014888.1 NM_014888 family with sequence similarity 3, member C FAM3C 10447 NM_001040020 /// NM_014888 0007275 // multicellular organismal development // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // non-traceable author statement 201890_at BE966236 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966236 /FEA=EST /DB_XREF=gi:11771437 /DB_XREF=est:601660172R1 /CLONE=IMAGE:3905920 /UG=Hs.75319 ribonucleotide reductase M2 polypeptide /FL=gb:NM_001034.1 BE966236 ribonucleotide reductase M2 RRM2 6241 NM_001034 /// NM_001165931 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009186 // deoxyribonucleoside diphosphate metabolic process // inferred from electronic annotation /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201891_s_at NM_004048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004048.1 /DEF=Homo sapiens beta-2-microglobulin (B2M), mRNA. /FEA=mRNA /GEN=B2M /PROD=beta-2-microglobulin /DB_XREF=gi:4757825 /UG=Hs.75415 beta-2-microglobulin /FL=gb:AB021288.1 gb:NM_004048.1 NM_004048 beta-2-microglobulin B2M 567 NM_004048 /// XM_005254549 /// XM_006725182 0001895 // retina homeostasis // inferred from expression pattern /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042026 // protein refolding // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0031905 // early endosome lumen // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 201892_s_at NM_000884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000884.1 /DEF=Homo sapiens IMP (inosine monophosphate) dehydrogenase 2 (IMPDH2), mRNA. /FEA=mRNA /GEN=IMPDH2 /PROD=IMP (inosine monophosphate) dehydrogenase 2 /DB_XREF=gi:4504688 /UG=Hs.75432 IMP (inosine monophosphate) dehydrogenase 2 /FL=gb:J04208.1 gb:NM_000884.1 NM_000884 IMP (inosine 5'-monophosphate) dehydrogenase 2 IMPDH2 3615 NM_000884 /// XM_006713128 0006051 // N-acetylmannosamine metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006177 // GMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003938 // IMP dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018580 // nitronate monooxygenase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047465 // N-acylglucosamine-6-phosphate 2-epimerase activity // inferred from electronic annotation 201893_x_at AF138300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF138300.1 /DEF=Homo sapiens decorin variant A mRNA, complete cds. /FEA=CDS /PROD=decorin variant A /DB_XREF=gi:5532410 /UG=Hs.76152 decorin /FL=gb:M14219.1 gb:NM_001920.1 gb:AF138300.1 gb:AF138304.1 AF138300 decorin DCN 1634 NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201894_s_at NM_001920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001920.1 /DEF=Homo sapiens decorin (DCN), mRNA. /FEA=mRNA /GEN=DCN /PROD=decorin /DB_XREF=gi:4503270 /UG=Hs.76152 decorin /FL=gb:M14219.1 gb:NM_001920.1 gb:AF138300.1 gb:AF138304.1 NM_001920 signal sequence receptor, alpha SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201895_at NM_001654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001654.1 /DEF=Homo sapiens v-raf murine sarcoma 3611 viral oncogene homolog 1 (ARAF1), mRNA. /FEA=mRNA /GEN=ARAF1 /PROD=v-raf murine sarcoma 3611 viral oncogene homolog1 /DB_XREF=gi:4502192 /UG=Hs.77183 v-raf murine sarcoma 3611 viral oncogene homolog 1 /FL=gb:BC002466.1 gb:NM_001654.1 NM_001654 A-Raf proto-oncogene, serine/threonine kinase ARAF 369 NM_001256196 /// NM_001256197 /// NM_001654 /// XM_006724529 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201896_s_at BC001425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001425.1 /DEF=Homo sapiens, Similar to differential display and activated by p53, clone MGC:1780, mRNA, complete cds. /FEA=mRNA /PROD=Similar to differential display and activated byp53 /DB_XREF=gi:12655140 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1 BC001425 proline/serine-rich coiled-coil 1 PSRC1 84722 NM_001005290 /// NM_001032290 /// NM_001032291 /// NM_032636 /// XM_005271282 /// XM_005271283 /// XM_006710982 /// XM_006710983 /// XM_006710984 /// XM_006710985 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007080 // mitotic metaphase plate congression // inferred from direct assay /// 0009987 // cellular process // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0031116 // positive regulation of microtubule polymerization // inferred from sequence or structural similarity /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060236 // regulation of mitotic spindle organization // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 201897_s_at NM_001826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001826.1 /DEF=Homo sapiens CDC28 protein kinase 1 (CKS1), mRNA. /FEA=mRNA /GEN=CKS1 /PROD=CDC28 protein kinase 1 /DB_XREF=gi:4502856 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1 NM_001826 CDC28 protein kinase regulatory subunit 1B CKS1B 1163 NM_001826 /// NR_024163 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation 201898_s_at AI126625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI126625 /FEA=EST /DB_XREF=gi:3595139 /DB_XREF=est:qd83a12.x1 /CLONE=IMAGE:1736062 /UG=Hs.80612 ubiquitin-conjugating enzyme E2A (RAD6 homolog) /FL=gb:M74524.1 gb:NM_003336.1 AI126625 ubiquitin-conjugating enzyme E2A UBE2A 7319 NM_001282161 /// NM_003336 /// NM_181762 /// NM_181777 0000209 // protein polyubiquitination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from genetic interaction /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201899_s_at NM_003336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003336.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A), mRNA. /FEA=mRNA /GEN=UBE2A /PROD=ubiquitin-conjugating enzyme E2A (RAD6 homolog) /DB_XREF=gi:4507768 /UG=Hs.80612 ubiquitin-conjugating enzyme E2A (RAD6 homolog) /FL=gb:M74524.1 gb:NM_003336.1 NM_003336 ubiquitin-conjugating enzyme E2A UBE2A 7319 NM_001282161 /// NM_003336 /// NM_181762 /// NM_181777 0000209 // protein polyubiquitination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from genetic interaction /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201900_s_at NM_006066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006066.1 /DEF=Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde reductase) (AKR1A1), mRNA. /FEA=mRNA /GEN=AKR1A1 /PROD=aldo-keto reductase family 1, member A1(aldehyde reductase) /DB_XREF=gi:5174390 /UG=Hs.89529 aldo-keto reductase family 1, member A1 (aldehyde reductase) /FL=gb:BC000670.1 gb:J04794.1 gb:NM_006066.1 NM_006066 aldo-keto reductase family 1, member A1 (aldehyde reductase) AKR1A1 10327 NM_001202413 /// NM_001202414 /// NM_006066 /// NM_153326 0006006 // glucose metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0019853 // L-ascorbic acid biosynthetic process // inferred from electronic annotation /// 0042840 // D-glucuronate catabolic process // inferred from electronic annotation /// 0046185 // aldehyde catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // traceable author statement /// 0008106 // alcohol dehydrogenase (NADP+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047939 // L-glucuronate reductase activity // inferred from electronic annotation 201901_s_at Z14077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z14077.1 /DEF=H.sapiens mRNA for YY1NF-E1 protein. /FEA=mRNA /PROD=YY1 NF-E1 /DB_XREF=gi:38010 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 Z14077 YY1 transcription factor YY1 7528 NM_003403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201902_s_at BG390664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG390664 /FEA=EST /DB_XREF=gi:13284112 /DB_XREF=est:602415258F1 /CLONE=IMAGE:4523487 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 BG390664 YY1 transcription factor YY1 7528 NM_003403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201903_at NM_003365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003365.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase core protein I (UQCRC1), mRNA. /FEA=mRNA /GEN=UQCRC1 /PROD=ubiquinol-cytochrome c reductase core protein I /DB_XREF=gi:4507840 /UG=Hs.119251 ubiquinol-cytochrome c reductase core protein I /FL=gb:L16842.1 gb:NM_003365.1 gb:D26485.1 NM_003365 ubiquinol-cytochrome c reductase core protein I UQCRC1 7384 NM_003365 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008121 // ubiquinol-cytochrome-c reductase activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201904_s_at BF031714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF031714 /FEA=EST /DB_XREF=gi:10739426 /DB_XREF=est:601558023F1 /CLONE=IMAGE:3827909 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1 BF031714 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201905_s_at BF590317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF590317 /FEA=EST /DB_XREF=gi:11682641 /DB_XREF=est:nab22h04.x1 /CLONE=IMAGE:3266910 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1 BF590317 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201906_s_at NM_005808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005808.1 /DEF=Homo sapiens HYA22 protein (HYA22), mRNA. /FEA=mRNA /GEN=HYA22 /PROD=HYA22 protein /DB_XREF=gi:5031774 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1 NM_005808 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201907_x_at U49262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49262.1 /DEF=Human dishevelled (DVL) mRNA, complete cds. /FEA=mRNA /GEN=DVL /PROD=dishevelled /DB_XREF=gi:1277022 /UG=Hs.174044 dishevelled 3 (homologous to Drosophila dsh) /FL=gb:U49262.1 gb:D86963.1 gb:U75651.1 gb:AF006013.1 gb:NM_004423.2 U49262 dishevelled segment polarity protein 3 DVL3 1857 NM_004423 /// XM_005247172 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // not recorded 0002020 // protease binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201908_at NM_004423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004423.2 /DEF=Homo sapiens dishevelled 3 (homologous to Drosophila dsh) (DVL3), mRNA. /FEA=mRNA /GEN=DVL3 /PROD=dishevelled 3 /DB_XREF=gi:6806886 /UG=Hs.174044 dishevelled 3 (homologous to Drosophila dsh) /FL=gb:U49262.1 gb:D86963.1 gb:U75651.1 gb:AF006013.1 gb:NM_004423.2 NM_004423 dishevelled segment polarity protein 3 DVL3 1857 NM_004423 /// XM_005247172 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // not recorded 0002020 // protease binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201909_at NM_001008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001008.1 /DEF=Homo sapiens ribosomal protein S4, Y-linked (RPS4Y), mRNA. /FEA=mRNA /GEN=RPS4Y /PROD=ribosomal protein S4, Y-linked /DB_XREF=gi:4506726 /UG=Hs.180911 ribosomal protein S4, Y-linked /FL=gb:M58459.1 gb:NM_001008.1 gb:AF116711.1 NM_001008 ribosomal protein S4, Y-linked 1 RPS4Y1 6192 NM_001008 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005844 // polysome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0019843 // rRNA binding // inferred from electronic annotation 201910_at BF213279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF213279 /FEA=EST /DB_XREF=gi:11106865 /DB_XREF=est:601844779F1 /CLONE=IMAGE:4070203 /UG=Hs.183738 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) /FL=gb:AB008430.1 gb:NM_005766.1 BF213279 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) FARP1 10160 NM_001001715 /// NM_001286839 /// NM_005766 /// XM_006719913 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0048365 // Rac GTPase binding // inferred from electronic annotation 201911_s_at NM_005766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005766.1 /DEF=Homo sapiens FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (FARP1), mRNA. /FEA=mRNA /GEN=FARP1 /PROD=FERM, RhoGEF, and pleckstrin domain protein 1 /DB_XREF=gi:5031632 /UG=Hs.183738 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) /FL=gb:AB008430.1 gb:NM_005766.1 NM_005766 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) FARP1 10160 NM_001001715 /// NM_001286839 /// NM_005766 /// XM_006719913 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0048365 // Rac GTPase binding // inferred from electronic annotation 201912_s_at NM_002094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002094.1 /DEF=Homo sapiens G1 to S phase transition 1 (GSPT1), mRNA. /FEA=mRNA /GEN=GSPT1 /PROD=G1 to S phase transition 1 /DB_XREF=gi:4504166 /UG=Hs.2707 G1 to S phase transition 1 /FL=gb:NM_002094.1 NM_002094 G1 to S phase transition 1 GSPT1 2935 NM_001130006 /// NM_001130007 /// NM_002094 /// XM_005255274 /// XM_005255275 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from mutant phenotype /// 0006479 // protein methylation // inferred from direct assay 0005622 // intracellular // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003747 // translation release factor activity // inferred from mutant phenotype /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201913_s_at NM_025233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025233.1 /DEF=Homo sapiens nucleotide binding protein (NBP), mRNA. /FEA=mRNA /GEN=NBP /PROD=nucleotide binding protein /DB_XREF=gi:13376837 /UG=Hs.296422 nucleotide binding protein /FL=gb:NM_025233.1 gb:AF208536.1 NM_025233 CoA synthase COASY 80347 NM_001042529 /// NM_001042530 /// NM_001042531 /// NM_001042532 /// NM_025233 /// XM_006722116 /// XR_429926 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0015937 // coenzyme A biosynthetic process // traceable author statement /// 0015939 // pantothenate metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004140 // dephospho-CoA kinase activity // inferred from direct assay /// 0004595 // pantetheine-phosphate adenylyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 201914_s_at AK001465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001465.1 /DEF=Homo sapiens cDNA FLJ10603 fis, clone NT2RP2005012, highly similar to Homo sapiens mRNA for SEC63 protein. /FEA=mRNA /DB_XREF=gi:7022740 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1 AK001465 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201915_at AI806665 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806665 /FEA=EST /DB_XREF=gi:5393231 /DB_XREF=est:wf35c05.x1 /CLONE=IMAGE:2357576 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1 AI806665 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201916_s_at NM_007214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007214.1 /DEF=Homo sapiens SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like (SEC63L), mRNA. /FEA=mRNA /GEN=SEC63L /PROD=SEC63, endoplasmic reticulum transloconcomponent (S. cerevisiae) like /DB_XREF=gi:6005871 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1 NM_007214 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201917_s_at AI694452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694452 /FEA=EST /DB_XREF=gi:4971792 /DB_XREF=est:wd83h07.x1 /CLONE=IMAGE:2338237 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AI694452 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201918_at AI927944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927944 /FEA=EST /DB_XREF=gi:5663908 /DB_XREF=est:wp03g05.x1 /CLONE=IMAGE:2463800 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AI927944 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201919_at AL049246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049246.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C053 (from clone DKFZp564C053). /FEA=mRNA /DB_XREF=gi:4499983 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AL049246 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201920_at NM_005415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005415.2 /DEF=Homo sapiens solute carrier family 20 (phosphate transporter), member 1 (SLC20A1), mRNA. /FEA=mRNA /GEN=SLC20A1 /PROD=solute carrier family 20 (phosphatetransporter), member 1 /DB_XREF=gi:7382462 /UG=Hs.78452 solute carrier family 20 (phosphate transporter), member 1 /FL=gb:L20859.1 gb:NM_005415.2 NM_005415 solute carrier family 20 (phosphate transporter), member 1 SLC20A1 6574 NM_005415 /// XM_005263743 /// XM_006712712 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0035435 // phosphate ion transmembrane transport // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0004872 // receptor activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0005316 // high affinity inorganic phosphate:sodium symporter activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 201921_at NM_004125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004125.1 /DEF=Homo sapiens guanine nucleotide binding protein 10 (GNG10), mRNA. /FEA=mRNA /GEN=GNG10 /PROD=guanine nucleotide binding protein 10 /DB_XREF=gi:4758445 /UG=Hs.79126 guanine nucleotide binding protein 10 /FL=gb:NM_004125.1 gb:U31383.1 NM_004125 guanine nucleotide binding protein (G protein), gamma 10 GNG10 2790 NM_001017998 /// NM_001198664 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 201922_at NM_014886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014886.1 /DEF=Homo sapiens hypothetical protein (YR-29), mRNA. /FEA=mRNA /GEN=YR-29 /PROD=hypothetical protein /DB_XREF=gi:7662676 /UG=Hs.8170 hypothetical protein /FL=gb:AF077615.1 gb:BC005288.1 gb:NM_014886.1 NM_014886 NSA2 ribosome biogenesis homolog (S. cerevisiae) NSA2 10412 NM_001271665 /// NM_014886 /// NR_073403 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201923_at NM_006406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006406.1 /DEF=Homo sapiens thioredoxin peroxidase (antioxidant enzyme) (AOE372), mRNA. /FEA=mRNA /GEN=AOE372 /PROD=thioredoxin peroxidase /DB_XREF=gi:5453548 /UG=Hs.83383 thioredoxin peroxidase (antioxidant enzyme) /FL=gb:BC003609.1 gb:NM_006406.1 gb:U25182.1 NM_006406 peroxiredoxin 4 PRDX4 10549 NM_006406 /// XM_005274438 0007252 // I-kappaB phosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000255 // negative regulation of male germ cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201924_at NM_005935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005935.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 (MLLT2), mRNA. /FEA=mRNA /GEN=MLLT2 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 2 /DB_XREF=gi:5174572 /UG=Hs.114765 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 /FL=gb:L13773.1 gb:L25050.1 gb:NM_005935.1 NM_005935 AF4/FMR2 family, member 1 AFF1 4299 NM_001166693 /// NM_005935 /// XM_005263007 /// XM_005263008 /// XM_005263009 /// XM_005263010 /// XM_005263011 /// XM_005263012 /// XM_005263013 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201925_s_at NM_000574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000574.1 /DEF=Homo sapiens decay accelerating factor for complement (CD55, Cromer blood group system) (DAF), mRNA. /FEA=mRNA /GEN=DAF /PROD=decay accelerating factor for complement (CD55,Cromer blood group system) /DB_XREF=gi:10835142 /UG=Hs.1369 decay accelerating factor for complement (CD55, Cromer blood group system) /FL=gb:NM_000574.1 gb:BC001288.1 gb:M31516.1 NM_000574 CD55 molecule, decay accelerating factor for complement (Cromer blood group) CD55 1604 NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077 0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 201926_s_at BC001288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001288.1 /DEF=Homo sapiens, Similar to decay accelerating factor for complement (CD55, Cromer blood group system), clone MGC:5192, mRNA, complete cds. /FEA=mRNA /PROD=Similar to decay accelerating factor forcomplement (CD55, Cromer blood group system) /DB_XREF=gi:12654888 /UG=Hs.1369 decay accelerating factor for complement (CD55, Cromer blood group system) /FL=gb:NM_000574.1 gb:BC001288.1 gb:M31516.1 BC001288 CD55 molecule, decay accelerating factor for complement (Cromer blood group) CD55 1604 NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077 0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 201927_s_at BG292559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG292559 /FEA=EST /DB_XREF=gi:13051484 /DB_XREF=est:602386951F1 /CLONE=IMAGE:4515829 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2 BG292559 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201928_at AA194254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA194254 /FEA=EST /DB_XREF=gi:1783969 /DB_XREF=est:zr39d09.s1 /CLONE=IMAGE:665777 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2 AA194254 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201929_s_at NM_003628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003628.2 /DEF=Homo sapiens plakophilin 4 (PKP4), mRNA. /FEA=mRNA /GEN=PKP4 /PROD=plakophilin 4 /DB_XREF=gi:6806894 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2 NM_003628 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201930_at NM_005915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005915.2 /DEF=Homo sapiens minichromosome maintenance deficient (mis5, S. pombe) 6 (MCM6), mRNA. /FEA=mRNA /GEN=MCM6 /PROD=minichromosome maintenance deficient (mis5, S.pombe) 6 /DB_XREF=gi:7427518 /UG=Hs.155462 minichromosome maintenance deficient (mis5, S. pombe) 6 /FL=gb:U46838.1 gb:D84557.1 gb:NM_005915.2 NM_005915 minichromosome maintenance complex component 6 MCM6 4175 NM_005915 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201931_at NM_000126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000126.1 /DEF=Homo sapiens electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) (ETFA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ETFA /PROD=electron transfer flavoprotein, alphapolypeptide /DB_XREF=gi:4503606 /UG=Hs.169919 electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) /FL=gb:J04058.1 gb:NM_000126.1 NM_000126 electron-transfer-flavoprotein, alpha polypeptide ETFA 2108 NM_000126 /// NM_001127716 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 201932_at NM_006369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006369.1 /DEF=Homo sapiens MUF1 protein (MUF1), mRNA. /FEA=mRNA /GEN=MUF1 /PROD=MUF1 protein /DB_XREF=gi:5453747 /UG=Hs.172210 MUF1 protein /FL=gb:BC004953.1 gb:NM_006369.1 NM_006369 leucine rich repeat containing 41 LRRC41 10489 NM_006369 /// XM_005270376 0016567 // protein ubiquitination // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 201933_at NM_002768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002768.1 /DEF=Homo sapiens procollagen (type III) N-endopeptidase (PCOLN3), mRNA. /FEA=mRNA /GEN=PCOLN3 /PROD=procollagen (type III) N-endopeptidase /DB_XREF=gi:4506138 /UG=Hs.183138 procollagen (type III) N-endopeptidase /FL=gb:U58048.1 gb:NM_002768.1 gb:AF281063.1 NM_002768 charged multivesicular body protein 1A CHMP1A 5119 NM_001083314 /// NM_002768 /// NR_046418 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0016458 // gene silencing // inferred from direct assay /// 0045014 // negative regulation of transcription by glucose // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201934_at N92524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92524 /FEA=EST /DB_XREF=gi:1264833 /DB_XREF=est:zb28d02.s1 /CLONE=IMAGE:304899 /UG=Hs.194110 hypothetical protein PRO2730 /FL=gb:AF132207.1 gb:NM_025222.1 N92524 WD repeat domain 82 WDR82 80335 NM_025222 0051568 // histone H3-K4 methylation // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay 201935_s_at AI768122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768122 /FEA=EST /DB_XREF=gi:5234631 /DB_XREF=est:wg81d04.x1 /CLONE=IMAGE:2371495 /UG=Hs.25732 eukaryotic translation initiation factor 4 gamma, 3 /FL=gb:NM_003760.2 gb:AF012072.2 AI768122 eukaryotic translation initiation factor 4 gamma, 3 EIF4G3 8672 NM_001198801 /// NM_001198802 /// NM_001198803 /// NM_003760 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000339 // RNA cap binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201936_s_at NM_003760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003760.2 /DEF=Homo sapiens eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), mRNA. /FEA=mRNA /GEN=EIF4G3 /PROD=eukaryotic translation initiation factor 4gamma, 3 /DB_XREF=gi:10092600 /UG=Hs.25732 eukaryotic translation initiation factor 4 gamma, 3 /FL=gb:NM_003760.2 gb:AF012072.2 NM_003760 eukaryotic translation initiation factor 4 gamma, 3 EIF4G3 8672 NM_001198801 /// NM_001198802 /// NM_001198803 /// NM_003760 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000339 // RNA cap binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201937_s_at NM_012100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012100.1 /DEF=Homo sapiens aspartyl aminopeptidase (DNPEP), mRNA. /FEA=mRNA /GEN=DNPEP /PROD=aspartyl aminopeptidase /DB_XREF=gi:6912247 /UG=Hs.258551 aspartyl aminopeptidase /FL=gb:BC000653.1 gb:AF005050.2 gb:NM_012100.1 NM_012100 aspartyl aminopeptidase DNPEP 23549 NM_012100 /// XM_005246430 /// XM_005246431 /// XM_005246432 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201938_at NM_004642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004642.1 /DEF=Homo sapiens deleted in oral cancer (mouse, homolog) 1 (DOC1), mRNA. /FEA=mRNA /GEN=DOC1 /PROD=deleted in oral cancer (mouse, homolog) 1 /DB_XREF=gi:4758187 /UG=Hs.3436 deleted in oral cancer (mouse, homolog) 1 /FL=gb:AB006077.1 gb:AF006484.1 gb:NM_004642.1 NM_004642 cyclin-dependent kinase 2 associated protein 1 CDK2AP1 8099 NM_001270433 /// NM_001270434 /// NM_004642 /// NR_073007 /// NR_073008 0000084 // mitotic S phase // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0003677 // DNA binding // traceable author statement 201939_at NM_006622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006622.1 /DEF=Homo sapiens serum-inducible kinase (SNK), mRNA. /FEA=mRNA /GEN=SNK /PROD=serum-inducible kinase /DB_XREF=gi:5730054 /UG=Hs.3838 serum-inducible kinase /FL=gb:AF059617.1 gb:NM_006622.1 gb:AF223574.1 NM_006622 polo-like kinase 2 PLK2 10769 NM_001252226 /// NM_006622 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from sequence or structural similarity /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046599 // regulation of centriole replication // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity 0005622 // intracellular // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 201940_at AA897514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA897514 /FEA=EST /DB_XREF=gi:3034134 /DB_XREF=est:aj62b12.s1 /CLONE=IMAGE:1394879 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 AA897514 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201941_at BE349147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE349147 /FEA=EST /DB_XREF=gi:9261086 /DB_XREF=est:ht51f05.x1 /CLONE=IMAGE:3150273 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 BE349147 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201942_s_at D85390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D85390.1 /DEF=Homo sapiens mRNA for gp180-carboxypeptidase D-like enzyme, complete cds. /FEA=mRNA /PROD=gp180-carboxypeptidase D-like enzyme /DB_XREF=gi:3641620 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 D85390 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201943_s_at NM_001304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001304.2 /DEF=Homo sapiens carboxypeptidase D (CPD), mRNA. /FEA=mRNA /GEN=CPD /PROD=carboxypeptidase D precursor /DB_XREF=gi:8051580 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 NM_001304 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201944_at NM_000521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000521.2 /DEF=Homo sapiens hexosaminidase B (beta polypeptide) (HEXB), mRNA. /FEA=mRNA /GEN=HEXB /PROD=hexosaminidase B preproprotein /DB_XREF=gi:13128866 /UG=Hs.51043 hexosaminidase B (beta polypeptide) /FL=gb:NM_000521.2 gb:M19735.1 NM_000521 hexosaminidase B (beta polypeptide) HEXB 3074 NM_000521 /// NM_001292004 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008049 // male courtship behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0031323 // regulation of cellular metabolic process // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201945_at NM_002569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002569.1 /DEF=Homo sapiens paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) (PACE), mRNA. /FEA=mRNA /GEN=PACE /PROD=paired basic amino acid cleaving enzyme (furin,membrane associated receptor protein) /DB_XREF=gi:4505578 /UG=Hs.59242 paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) /FL=gb:NM_002569.1 NM_002569 furin (paired basic amino acid cleaving enzyme) FURIN 5045 NM_001289823 /// NM_001289824 /// NM_002569 /// XM_005254931 /// XM_005254932 0006465 // signal peptide processing // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0016485 // protein processing // inferred from mutant phenotype /// 0016486 // peptide hormone processing // inferred from direct assay /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0019058 // viral life cycle // inferred from expression pattern /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032804 // negative regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032904 // negative regulation of nerve growth factor production // inferred from direct assay /// 0032911 // negative regulation of transforming growth factor beta1 production // inferred from mutant phenotype /// 0032940 // secretion by cell // inferred from direct assay /// 0042176 // regulation of protein catabolic process // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred by curator /// 0052548 // regulation of endopeptidase activity // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 201946_s_at AL545982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL545982 /FEA=EST /DB_XREF=gi:12878676 /DB_XREF=est:AL545982 /CLONE=CS0DI023YD15 (5 prime) /UG=Hs.6456 chaperonin containing TCP1, subunit 2 (beta) /FL=gb:AF026293.1 gb:AF026166.1 gb:NM_006431.1 AL545982 chaperonin containing TCP1, subunit 2 (beta) CCT2 10576 NM_001198842 /// NM_006431 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 201947_s_at NM_006431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006431.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 2 (beta) (CCT2), mRNA. /FEA=mRNA /GEN=CCT2 /PROD=chaperonin containing TCP1, subunit 2 (beta) /DB_XREF=gi:5453602 /UG=Hs.6456 chaperonin containing TCP1, subunit 2 (beta) /FL=gb:AF026293.1 gb:AF026166.1 gb:NM_006431.1 NM_006431 chaperonin containing TCP1, subunit 2 (beta) CCT2 10576 NM_001198842 /// NM_006431 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 201948_at NM_013285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013285.1 /DEF=Homo sapiens nucleolar GTPase (HUMAUANTIG), mRNA. /FEA=mRNA /GEN=HUMAUANTIG /PROD=nucleolar GTPase /DB_XREF=gi:7019418 /UG=Hs.75528 nucleolar GTPase /FL=gb:BC000107.1 gb:L05425.1 gb:NM_013285.1 NM_013285 guanine nucleotide binding protein-like 2 (nucleolar) GNL2 29889 NM_013285 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // non-traceable author statement /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201949_x_at AL572341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL572341 /FEA=EST /DB_XREF=gi:12930514 /DB_XREF=est:AL572341 /CLONE=CS0DI007YC13 (3 prime) /UG=Hs.76368 capping protein (actin filament) muscle Z-line, beta /FL=gb:NM_004930.1 gb:U03271.1 AL572341 capping protein (actin filament) muscle Z-line, beta CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 201950_x_at NM_004930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004930.1 /DEF=Homo sapiens capping protein (actin filament) muscle Z-line, beta (CAPZB), mRNA. /FEA=mRNA /GEN=CAPZB /PROD=F-actin capping protein beta subunit /DB_XREF=gi:4826658 /UG=Hs.76368 capping protein (actin filament) muscle Z-line, beta /FL=gb:NM_004930.1 gb:U03271.1 NM_004930 capping protein (actin filament) muscle Z-line, beta CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 201951_at BF242905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF242905 /FEA=EST /DB_XREF=gi:11156833 /DB_XREF=est:601877949F1 /CLONE=IMAGE:4106028 /UG=Hs.10247 activated leucocyte cell adhesion molecule /FL=gb:NM_001627.1 gb:L38608.1 BF242905 activated leukocyte cell adhesion molecule ALCAM 214 NM_001243280 /// NM_001243281 /// NM_001243283 /// NM_001627 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201952_at AA156721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156721 /FEA=EST /DB_XREF=gi:1728335 /DB_XREF=est:zl18b04.s1 /CLONE=IMAGE:502255 /UG=Hs.10247 activated leucocyte cell adhesion molecule /FL=gb:NM_001627.1 gb:L38608.1 AA156721 activated leukocyte cell adhesion molecule ALCAM 214 NM_001243280 /// NM_001243281 /// NM_001243283 /// NM_001627 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201953_at NM_006384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006384.2 /DEF=Homo sapiens calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) (SIP2-28), mRNA. /FEA=mRNA /GEN=SIP2-28 /PROD=calcium and integrin binding protein /DB_XREF=gi:9951921 /UG=Hs.10803 calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) /FL=gb:BC000846.1 gb:U83236.1 gb:U82226.1 gb:U85611.1 gb:NM_006384.2 NM_006384 calcium and integrin binding 1 (calmyrin) CIB1 10519 NM_001277764 /// NM_006384 /// NR_102427 /// NR_102428 /// XM_006720375 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007113 // endomitotic cell cycle // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // non-traceable author statement /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0038163 // thrombopoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051302 // regulation of cell division // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from genetic interaction /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0090314 // positive regulation of protein targeting to membrane // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay /// 2000256 // positive regulation of male germ cell proliferation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0032433 // filopodium tip // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005509 // calcium ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0043495 // protein anchor // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201954_at NM_005720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005720.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 1A (41 kD) (ARPC1B), mRNA. /FEA=mRNA /GEN=ARPC1B /PROD=actin related protein 23 complex, subunit 1A(41 kD) /DB_XREF=gi:5031600 /UG=Hs.11538 actin related protein 23 complex, subunit 1A (41 kD) /FL=gb:BC002562.1 gb:AF006084.1 gb:NM_005720.1 NM_005720 actin related protein 2/3 complex, subunit 1B, 41kDa ARPC1B 10095 NM_005720 /// XM_006715825 /// XM_006715826 0006928 // cellular component movement // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201955_at AL137784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137784 /DEF=Human DNA sequence from clone RP1-199J3 on chromosome 6 Contains ESTs, STSs, GSSs and CpG islands. Contains part of the gene for a novel protein similar to ubiquitin carboxyl-terminal hudrolase 16 (EC 3.1.2.15), a novel gene, the CCNC gene encodin... /FEA=mRNA /DB_XREF=gi:9863487 /UG=Hs.118442 cyclin C /FL=gb:NM_005190.2 AL137784 cyclin C CCNC 892 NM_001013399 /// NM_005190 /// XM_005267202 /// XM_006715594 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 201956_s_at NM_014236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014236.1 /DEF=Homo sapiens glyceronephosphate O-acyltransferase (GNPAT), mRNA. /FEA=mRNA /GEN=GNPAT /PROD=glyceronephosphate O-acyltransferase /DB_XREF=gi:7657133 /UG=Hs.12482 glyceronephosphate O-acyltransferase /FL=gb:BC000450.1 gb:AF043937.1 gb:NM_014236.1 NM_014236 glyceronephosphate O-acyltransferase GNPAT 8443 NM_014236 /// XM_005273313 /// XM_005273314 0006644 // phospholipid metabolic process // traceable author statement /// 0006650 // glycerophospholipid metabolic process // inferred from electronic annotation /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008611 // ether lipid biosynthetic process // inferred from direct assay /// 0008611 // ether lipid biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0070542 // response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004366 // glycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016287 // glycerone-phosphate O-acyltransferase activity // inferred from direct assay /// 0016287 // glycerone-phosphate O-acyltransferase activity // traceable author statement /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 201957_at AF324888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF324888.1 /DEF=Homo sapiens myosin phosphatase target subunit 2 mRNA, complete cds. /FEA=mRNA /PROD=myosin phosphatase target subunit 2 /DB_XREF=gi:12642661 /UG=Hs.130760 myosin phosphatase, target subunit 2 /FL=gb:AF324888.1 gb:AB003062.1 gb:NM_002481.1 AF324888 protein phosphatase 1, regulatory subunit 12B PPP1R12B 4660 NM_001167857 /// NM_001167858 /// NM_001197131 /// NM_002481 /// NM_032103 /// NM_032104 /// NM_032105 /// XM_005245199 /// XM_005245200 /// XM_005245201 /// XM_005245202 /// XM_005245204 /// XM_005245205 /// XM_005245206 /// XM_006711339 /// XR_426776 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement 201958_s_at NM_002481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002481.1 /DEF=Homo sapiens myosin phosphatase, target subunit 2 (MYPT2), mRNA. /FEA=mRNA /GEN=MYPT2 /PROD=myosin phosphatase target subunit 2 /DB_XREF=gi:4505318 /UG=Hs.130760 myosin phosphatase, target subunit 2 /FL=gb:AF324888.1 gb:AB003062.1 gb:NM_002481.1 NM_002481 protein phosphatase 1, regulatory subunit 12B PPP1R12B 4660 NM_001167857 /// NM_001167858 /// NM_001197131 /// NM_002481 /// NM_032103 /// NM_032104 /// NM_032105 /// XM_005245199 /// XM_005245200 /// XM_005245201 /// XM_005245202 /// XM_005245204 /// XM_005245205 /// XM_005245206 /// XM_006711339 /// XR_426776 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement 201959_s_at AA488899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA488899 /FEA=EST /DB_XREF=gi:2218501 /DB_XREF=est:aa55h06.s1 /CLONE=IMAGE:824891 /UG=Hs.151411 KIAA0916 protein /FL=gb:AF075587.1 gb:AF083244.1 gb:NM_015057.1 AA488899 MYC binding protein 2, E3 ubiquitin protein ligase MYCBP2 23077 NM_015057 /// XM_005266299 /// XM_005266300 /// XM_006719779 /// XM_006719780 /// XM_006719781 /// XM_006719782 /// XM_006719783 /// XM_006719784 /// XM_006719785 /// XM_006719786 /// XM_006719787 /// XM_006719788 /// XM_006719789 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0021785 // branchiomotor neuron axon guidance // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201960_s_at NM_015057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015057.1 /DEF=Homo sapiens KIAA0916 protein (KIAA0916), mRNA. /FEA=mRNA /GEN=KIAA0916 /PROD=KIAA0916 protein /DB_XREF=gi:7662379 /UG=Hs.151411 KIAA0916 protein /FL=gb:AF075587.1 gb:AF083244.1 gb:NM_015057.1 NM_015057 MYC binding protein 2, E3 ubiquitin protein ligase MYCBP2 23077 NM_015057 /// XM_005266299 /// XM_005266300 /// XM_006719779 /// XM_006719780 /// XM_006719781 /// XM_006719782 /// XM_006719783 /// XM_006719784 /// XM_006719785 /// XM_006719786 /// XM_006719787 /// XM_006719788 /// XM_006719789 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0021785 // branchiomotor neuron axon guidance // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201961_s_at AL583171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583171 /FEA=EST /DB_XREF=gi:12951876 /DB_XREF=est:AL583171 /CLONE=CS0DL009YA21 (3 prime) /UG=Hs.153639 hypothetical SBBI03 protein /FL=gb:AF077599.1 gb:NM_005785.1 AL583171 ring finger protein 41, E3 ubiquitin protein ligase RNF41 10193 NM_001242826 /// NM_005785 /// NM_194358 /// NM_194359 /// NR_040053 /// XM_005268561 0000209 // protein polyubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051896 // regulation of protein kinase B signaling // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005135 // interleukin-3 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031386 // protein tag // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201962_s_at NM_005785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005785.1 /DEF=Homo sapiens hypothetical SBBI03 protein (SBB103), mRNA. /FEA=mRNA /GEN=SBB103 /PROD=hypothetical SBBI03 protein /DB_XREF=gi:5032070 /UG=Hs.153639 hypothetical SBBI03 protein /FL=gb:AF077599.1 gb:NM_005785.1 NM_005785 ring finger protein 41, E3 ubiquitin protein ligase RNF41 10193 NM_001242826 /// NM_005785 /// NM_194358 /// NM_194359 /// NR_040053 /// XM_005268561 0000209 // protein polyubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051896 // regulation of protein kinase B signaling // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005135 // interleukin-3 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031386 // protein tag // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201963_at NM_021122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021122.2 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 2 (FACL2), mRNA. /FEA=mRNA /GEN=FACL2 /PROD=long-chain fatty-acid-Coenzyme A ligase 2 /DB_XREF=gi:12669906 /UG=Hs.154890 fatty-acid-Coenzyme A ligase, long-chain 2 /FL=gb:NM_021122.2 gb:D10040.1 NM_021122 acyl-CoA synthetase long-chain family member 1 ACSL1 2180 NM_001286708 /// NM_001286710 /// NM_001286711 /// NM_001286712 /// NM_001995 /// XM_005262827 /// XM_005262828 /// XM_005262829 /// XM_005262831 /// XM_006714138 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033211 // adiponectin-activated signaling pathway // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042178 // xenobiotic catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201964_at N64643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64643 /FEA=EST /DB_XREF=gi:1212472 /DB_XREF=est:yz87a06.s1 /CLONE=IMAGE:290002 /UG=Hs.154919 KIAA0625 protein /FL=gb:NM_015046.1 N64643 senataxin SETX 23064 NM_015046 /// XM_005272171 /// XM_005272172 /// XM_005272173 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003678 // DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201965_s_at NM_015046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015046.1 /DEF=Homo sapiens KIAA0625 protein (KIAA0625), mRNA. /FEA=mRNA /GEN=KIAA0625 /PROD=KIAA0625 protein /DB_XREF=gi:7662211 /UG=Hs.154919 KIAA0625 protein /FL=gb:NM_015046.1 NM_015046 senataxin SETX 23064 NM_015046 /// XM_005272171 /// XM_005272172 /// XM_005272173 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003678 // DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201966_at NM_004550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004550.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Q reductase) (NDUFS2), mRNA. /FEA=mRNA /GEN=NDUFS2 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 2(49kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758785 /UG=Hs.173611 NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Q reductase) /FL=gb:BC001456.1 gb:BC000170.2 gb:AF050640.1 gb:AF013160.1 gb:NM_004550.1 NM_004550 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) NDUFS2 4720 NM_001166159 /// NM_004550 /// XM_005245208 /// XM_005245209 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 201967_at NM_005777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005777.1 /DEF=Homo sapiens RNA binding motif protein 6 (RBM6), mRNA. /FEA=mRNA /GEN=RBM6 /PROD=RNA binding motif protein 6 /DB_XREF=gi:5032032 /UG=Hs.173993 RNA binding motif protein 6 /FL=gb:AF042857.1 gb:AF069517.1 gb:U50839.1 gb:AF091264.1 gb:NM_005777.1 NM_005777 RNA binding motif protein 6 RBM6 10180 NM_001167582 /// NM_005777 /// XM_005264784 /// XM_005264785 /// XM_005264786 /// XM_005264787 /// XM_005264788 /// XM_006712916 0006396 // RNA processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201968_s_at NM_002633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002633.1 /DEF=Homo sapiens phosphoglucomutase 1 (PGM1), mRNA. /FEA=mRNA /GEN=PGM1 /PROD=phosphoglucomutase 1 /DB_XREF=gi:4505764 /UG=Hs.1869 phosphoglucomutase 1 /FL=gb:BC001756.1 gb:M83088.1 gb:NM_002633.1 NM_002633 phosphoglucomutase 1 PGM1 5236 NM_001172818 /// NM_001172819 /// NM_002633 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // not recorded /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0019388 // galactose catabolic process // not recorded /// 0019388 // galactose catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004614 // phosphoglucomutase activity // inferred from direct assay /// 0004614 // phosphoglucomutase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201969_at AW003362 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003362 /FEA=EST /DB_XREF=gi:5850278 /DB_XREF=est:wq65h01.x1 /CLONE=IMAGE:2476177 /UG=Hs.243886 nuclear autoantigenic sperm protein (histone-binding) /FL=gb:M97856.1 gb:NM_002482.1 AW003362 nuclear autoantigenic sperm protein (histone-binding) NASP 4678 NM_001195193 /// NM_002482 /// NM_152298 /// NM_172164 /// XM_005270888 /// XM_005270889 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0043486 // histone exchange // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from sequence or structural similarity 201970_s_at NM_002482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002482.1 /DEF=Homo sapiens nuclear autoantigenic sperm protein (histone-binding) (NASP), mRNA. /FEA=mRNA /GEN=NASP /PROD=nuclear autoantigenic sperm protein(histone-binding) /DB_XREF=gi:4505332 /UG=Hs.243886 nuclear autoantigenic sperm protein (histone-binding) /FL=gb:M97856.1 gb:NM_002482.1 NM_002482 nuclear autoantigenic sperm protein (histone-binding) NASP 4678 NM_001195193 /// NM_002482 /// NM_152298 /// NM_172164 /// XM_005270888 /// XM_005270889 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0043486 // histone exchange // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from sequence or structural similarity 201971_s_at NM_001690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001690.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 (ATP6A1), mRNA. /FEA=mRNA /GEN=ATP6A1 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), alpha polypeptide, 70kD, isoform 1 /DB_XREF=gi:4502304 /UG=Hs.281866 ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 /FL=gb:L09235.1 gb:NM_001690.1 gb:AF113129.1 NM_001690 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A ATP6V1A 523 NM_001690 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201972_at AF113129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113129.1 /DEF=Homo sapiens vacuolar ATPase isoform VA68 mRNA, complete cds. /FEA=mRNA /PROD=vacuolar ATPase isoform VA68 /DB_XREF=gi:6523820 /UG=Hs.281866 ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 /FL=gb:L09235.1 gb:NM_001690.1 gb:AF113129.1 AF113129 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A ATP6V1A 523 NM_001690 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201973_s_at AL550875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL550875 /FEA=EST /DB_XREF=gi:12888273 /DB_XREF=est:AL550875 /CLONE=CS0DI065YO01 (5 prime) /UG=Hs.289112 CGI-43 protein /FL=gb:NM_015622.1 gb:AF151801.1 AL550875 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) /// CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) CCZ1 /// CCZ1B 51622 /// 221960 NM_015622 /// NM_198097 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201974_s_at NM_015622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015622.1 /DEF=Homo sapiens CGI-43 protein (LOC51622), mRNA. /FEA=mRNA /GEN=LOC51622 /PROD=DKFZP586I1023 protein /DB_XREF=gi:11056021 /UG=Hs.289112 CGI-43 protein /FL=gb:NM_015622.1 gb:AF151801.1 NM_015622 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) CCZ1 51622 NM_015622 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201975_at NM_002956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002956.1 /DEF=Homo sapiens restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) (RSN), mRNA. /FEA=mRNA /GEN=RSN /PROD=restin (Reed-Steinberg cell-expressedintermediate filament-associated protein) /DB_XREF=gi:4506750 /UG=Hs.31638 restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) /FL=gb:NM_002956.1 NM_002956 CAP-GLY domain containing linker protein 1 CLIP1 6249 NM_001247997 /// NM_002956 /// NM_198240 /// XM_005253593 /// XM_005253594 /// XM_005253595 /// XM_006719551 /// XM_006719552 /// XM_006719553 /// XM_006719554 /// XM_006719555 0000278 // mitotic cell cycle // traceable author statement /// 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from mutant phenotype 0000776 // kinetochore // traceable author statement /// 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from mutant phenotype /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0044354 // macropinosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // non-traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 201976_s_at NM_012334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012334.1 /DEF=Homo sapiens myosin X (MYO10), mRNA. /FEA=mRNA /GEN=MYO10 /PROD=myosin X /DB_XREF=gi:11037056 /UG=Hs.61638 myosin X /FL=gb:NM_012334.1 gb:AF234532.1 gb:AF247457.2 NM_012334 myosin X MYO10 4651 NM_012334 /// XM_005248306 /// XM_005248307 /// XM_006714475 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030705 // cytoskeleton-dependent intracellular transport // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032433 // filopodium tip // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060002 // plus-end directed microfilament motor activity // inferred from sequence or structural similarity 201977_s_at AI539425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI539425 /FEA=EST /DB_XREF=gi:4453560 /DB_XREF=est:te46d03.x1 /CLONE=IMAGE:2089733 /UG=Hs.63510 KIAA0141 gene product /FL=gb:D50931.1 gb:NM_014773.1 AI539425 KIAA0141 KIAA0141 9812 NM_001142603 /// NM_014773 /// XM_005268547 /// XM_005268548 /// XM_005268549 /// XM_005268550 /// XM_005268551 /// XM_005268552 /// XM_006714812 /// XR_245861 /// XR_427782 /// XR_427783 0006915 // apoptotic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201978_s_at NM_014773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014773.1 /DEF=Homo sapiens KIAA0141 gene product (KIAA0141), mRNA. /FEA=mRNA /GEN=KIAA0141 /PROD=KIAA0141 gene product /DB_XREF=gi:7661939 /UG=Hs.63510 KIAA0141 gene product /FL=gb:D50931.1 gb:NM_014773.1 NM_014773 KIAA0141 KIAA0141 9812 NM_001142603 /// NM_014773 /// XM_005268547 /// XM_005268548 /// XM_005268549 /// XM_005268550 /// XM_005268551 /// XM_005268552 /// XM_006714812 /// XR_245861 /// XR_427782 /// XR_427783 0006915 // apoptotic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201979_s_at NM_006247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006247.1 /DEF=Homo sapiens protein phosphatase 5, catalytic subunit (PPP5C), mRNA. /FEA=mRNA /GEN=PPP5C /PROD=protein phosphatase 5, catalytic subunit /DB_XREF=gi:5453957 /UG=Hs.75180 protein phosphatase 5, catalytic subunit /FL=gb:BC001970.1 gb:NM_006247.1 NM_006247 protein phosphatase 5, catalytic subunit PPP5C 5536 NM_001204284 /// NM_006247 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043278 // response to morphine // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201980_s_at NM_012425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012425.2 /DEF=Homo sapiens Ras suppressor protein 1 (RSU1), mRNA. /FEA=mRNA /GEN=RSU1 /PROD=ras suppressor protein 1 /DB_XREF=gi:10800408 /UG=Hs.75551 Homo sapiens Ras suppressor protein 1 (RSU1), mRNA /FL=gb:NM_012425.2 NM_012425 Ras suppressor protein 1 RSU1 6251 NM_012425 /// NM_152724 /// XM_005252552 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201981_at AA148534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA148534 /FEA=EST /DB_XREF=gi:1721559 /DB_XREF=est:zl06d06.s1 /CLONE=IMAGE:491531 /UG=Hs.75874 pregnancy-associated plasma protein A /FL=gb:U28727.1 gb:NM_002581.1 AA148534 pregnancy-associated plasma protein A, pappalysin 1 PAPPA 5069 NM_002581 /// XM_006717129 0006508 // proteolysis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201982_s_at NM_002581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002581.1 /DEF=Homo sapiens pregnancy-associated plasma protein A (PAPPA), mRNA. /FEA=mRNA /GEN=PAPPA /PROD=pregnancy-associated plasma protein A /DB_XREF=gi:4505606 /UG=Hs.75874 pregnancy-associated plasma protein A /FL=gb:U28727.1 gb:NM_002581.1 NM_002581 pregnancy-associated plasma protein A, pappalysin 1 PAPPA 5069 NM_002581 /// XM_006717129 0006508 // proteolysis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201983_s_at AW157070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157070 /FEA=EST /DB_XREF=gi:6228471 /DB_XREF=est:au91e07.x1 /CLONE=IMAGE:2783652 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:NM_005228.1 AW157070 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 201984_s_at NM_005228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005228.1 /DEF=Homo sapiens epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) (EGFR), mRNA. /FEA=mRNA /GEN=EGFR /PROD=epidermal growth factor receptor (avianerythroblastic leukemia viral (v-erb-b) oncogene homolog) /DB_XREF=gi:4885198 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:NM_005228.1 NM_005228 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 201985_at NM_014846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014846.1 /DEF=Homo sapiens KIAA0196 gene product (KIAA0196), mRNA. /FEA=mRNA /GEN=KIAA0196 /PROD=KIAA0196 gene product /DB_XREF=gi:7661987 /UG=Hs.8294 KIAA0196 gene product /FL=gb:D83780.1 gb:NM_014846.1 NM_014846 KIAA0196 KIAA0196 9897 NM_014846 /// XM_005251120 0008219 // cell death // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay 201986_at AB011165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011165.1 /DEF=Homo sapiens mRNA for KIAA0593 protein, partial cds. /FEA=mRNA /GEN=KIAA0593 /PROD=KIAA0593 protein /DB_XREF=gi:3043709 /UG=Hs.11861 thyroid hormone receptor-associated protein, 240 kDa subunit /FL=gb:AF117754.1 gb:NM_005121.1 AB011165 mediator complex subunit 13 MED13 9969 NM_005121 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201987_at AI984051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984051 /FEA=EST /DB_XREF=gi:5811270 /DB_XREF=est:wt52h03.x1 /CLONE=IMAGE:2511125 /UG=Hs.11861 thyroid hormone receptor-associated protein, 240 kDa subunit /FL=gb:AF117754.1 gb:NM_005121.1 AI984051 mediator complex subunit 13 MED13 9969 NM_005121 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201988_s_at BF438056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF438056 /FEA=EST /DB_XREF=gi:11450573 /DB_XREF=est:7q66e01.x1 /CLONE=IMAGE:3703369 /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1 BF438056 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201989_s_at AL529409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL529409 /FEA=EST /DB_XREF=gi:12792902 /DB_XREF=est:AL529409 /CLONE=CS0DD006YM17 (3 prime) /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1 AL529409 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201990_s_at NM_001310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001310.1 /DEF=Homo sapiens cAMP responsive element binding protein-like 2 (CREBL2), mRNA. /FEA=mRNA /GEN=CREBL2 /PROD=cAMP responsive element binding protein-like 2 /DB_XREF=gi:4503034 /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1 NM_001310 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201991_s_at BF223224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223224 /FEA=EST /DB_XREF=gi:11130401 /DB_XREF=est:7q30g05.x1 /CLONE=IMAGE:3700017 /UG=Hs.149436 kinesin family member 5B /FL=gb:NM_004521.1 BF223224 kinesin family member 5B KIF5B 3799 NM_004521 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 201992_s_at NM_004521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004521.1 /DEF=Homo sapiens kinesin family member 5B (KIF5B), mRNA. /FEA=mRNA /GEN=KIF5B /PROD=kinesin family member 5B /DB_XREF=gi:4758647 /UG=Hs.149436 kinesin family member 5B /FL=gb:NM_004521.1 NM_004521 kinesin family member 5B KIF5B 3799 NM_004521 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 201993_x_at NM_005463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005463.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein D-like (HNRPDL), mRNA. /FEA=mRNA /GEN=HNRPDL /PROD=heterogeneous nuclear ribonucleoprotein D-like /DB_XREF=gi:4885422 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like /FL=gb:AB017019.1 gb:NM_005463.1 NM_005463 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201994_at NM_012286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012286.1 /DEF=Homo sapiens MORF-related gene X (KIAA0026), mRNA. /FEA=mRNA /GEN=KIAA0026 /PROD=MORF-related gene X /DB_XREF=gi:6912447 /UG=Hs.173714 MORF-related gene X /FL=gb:D14812.1 gb:AF100620.1 gb:NM_012286.1 gb:AF167174.1 NM_012286 mortality factor 4 like 2 MORF4L2 9643 NM_001142418 /// NM_001142419 /// NM_001142420 /// NM_001142421 /// NM_001142422 /// NM_001142423 /// NM_001142424 /// NM_001142425 /// NM_001142426 /// NM_001142427 /// NM_001142428 /// NM_001142429 /// NM_001142430 /// NM_001142431 /// NM_001142432 /// NM_012286 0001558 // regulation of cell growth // non-traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201995_at NM_000127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000127.1 /DEF=Homo sapiens exostoses (multiple) 1 (EXT1), mRNA. /FEA=mRNA /GEN=EXT1 /PROD=exostoses (multiple) 1 /DB_XREF=gi:4557570 /UG=Hs.184161 exostoses (multiple) 1 /FL=gb:BC001174.1 gb:NM_000127.1 NM_000127 exostosin glycosyltransferase 1 EXT1 2131 NM_000127 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0072498 // embryonic skeletal joint development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from sequence or structural similarity /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // inferred from sequence or structural similarity /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement 201996_s_at AL524033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL524033 /FEA=EST /DB_XREF=gi:12787526 /DB_XREF=est:AL524033 /CLONE=CS0DC003YL08 (3 prime) /UG=Hs.184245 KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog /FL=gb:NM_015001.1 AL524033 spen family transcriptional repressor SPEN 23013 NM_015001 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201997_s_at NM_015001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015001.1 /DEF=Homo sapiens KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog (KIAA0929), mRNA. /FEA=mRNA /GEN=KIAA0929 /PROD=KIAA0929 protein Msx2 interacting nuclear target(MINT) homolog /DB_XREF=gi:7657266 /UG=Hs.184245 KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog /FL=gb:NM_015001.1 NM_015001 spen family transcriptional repressor SPEN 23013 NM_015001 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201998_at AI743792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743792 /FEA=EST /DB_XREF=gi:5112080 /DB_XREF=est:wg53h11.x1 /CLONE=IMAGE:2368869 /UG=Hs.2554 sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) /FL=gb:NM_003032.1 AI743792 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ST6GAL1 6480 NM_003032 /// NM_173216 /// NM_173217 /// XM_005247717 /// XM_005247719 /// XM_005247720 /// XM_006713734 0006054 // N-acetylneuraminate metabolic process // inferred from direct assay /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003835 // beta-galactoside alpha-2,6-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 201999_s_at NM_006519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006519.1 /DEF=Homo sapiens t-complex-associated-testis-expressed 1-like 1 (TCTEL1), mRNA. /FEA=mRNA /GEN=TCTEL1 /PROD=t-complex-associated-testis-expressed 1-like 1 /DB_XREF=gi:5730084 /UG=Hs.266940 t-complex-associated-testis-expressed 1-like 1 /FL=gb:U56255.1 gb:D50663.1 gb:NM_006519.1 NM_006519 dynein, light chain, Tctex-type 1 DYNLT1 6993 NM_001291602 /// NM_001291603 /// NM_006519 /// XM_005267117 0000132 // establishment of mitotic spindle orientation // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation /// 0075521 // microtubule-dependent intracellular transport of viral material towards nucleus // inferred from electronic annotation /// 0075606 // transport of viral material towards nucleus // inferred from electronic annotation /// 0075733 // intracellular transport of virus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202000_at BC002772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002772.1 /DEF=Homo sapiens, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14), clone MGC:3686, mRNA, complete cds. /FEA=mRNA /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 6 (14kD, B14) /DB_XREF=gi:12803858 /UG=Hs.274416 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) /FL=gb:BC002772.1 gb:AF047182.1 gb:NM_002490.1 BC002772 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa NDUFA6 4700 NM_002490 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202001_s_at NM_002490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002490.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) (NDUFA6), mRNA. /FEA=mRNA /GEN=NDUFA6 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 6 (14kD, B14) /DB_XREF=gi:4505358 /UG=Hs.274416 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) /FL=gb:BC002772.1 gb:AF047182.1 gb:NM_002490.1 NM_002490 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa NDUFA6 4700 NM_002490 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202002_at AW072302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW072302 /FEA=EST /DB_XREF=gi:6027300 /DB_XREF=est:wz98h08.x1 /CLONE=IMAGE:2566911 /UG=Hs.32500 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC001918.1 gb:D16294.1 gb:NM_006111.1 AW072302 acetyl-CoA acyltransferase 2 ACAA2 10449 NM_006111 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay /// 1902109 // negative regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202003_s_at NM_006111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006111.1 /DEF=Homo sapiens acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) (ACAA2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACAA2 /PROD=acetyl-Coenzyme A acyltransferase 2(mitochondrial 3-oxoacyl-Coenzyme A thiolase) /DB_XREF=gi:5174428 /UG=Hs.32500 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC001918.1 gb:D16294.1 gb:NM_006111.1 NM_006111 acetyl-CoA acyltransferase 2 ACAA2 10449 NM_006111 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay /// 1902109 // negative regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202004_x_at NM_003001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003001.2 /DEF=Homo sapiens succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD (SDHC), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHC /PROD=succinate dehydrogenase complex, subunit Cprecursor /DB_XREF=gi:9257243 /UG=Hs.3577 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD /FL=gb:U57877.1 gb:NM_003001.2 NM_003001 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa SDHC 6391 NM_001035511 /// NM_001035512 /// NM_001035513 /// NM_001278172 /// NM_003001 /// NR_103459 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0045273 // respiratory chain complex II // traceable author statement /// 0045281 // succinate dehydrogenase complex // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202005_at NM_021978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021978.1 /DEF=Homo sapiens suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) (ST14), mRNA. /FEA=mRNA /GEN=ST14 /PROD=suppression of tumorigenicity 14 (coloncarcinoma, matriptase, epithin) /DB_XREF=gi:11415039 /UG=Hs.56937 suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) /FL=gb:AF057145.1 gb:NM_021978.1 gb:AB030036.1 gb:AF133086.1 gb:AF118224.2 NM_021978 suppression of tumorigenicity 14 (colon carcinoma) ST14 6768 NM_021978 0006508 // proteolysis // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 202006_at NM_002835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002835.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 12 (PTPN12), mRNA. /FEA=mRNA /GEN=PTPN12 /PROD=protein tyrosine phosphatase, non-receptor type12 /DB_XREF=gi:4506286 /UG=Hs.62 protein tyrosine phosphatase, non-receptor type 12 /FL=gb:D13380.1 gb:M93425.1 gb:NM_002835.1 NM_002835 protein tyrosine phosphatase, non-receptor type 12 PTPN12 5782 NM_001131008 /// NM_001131009 /// NM_002835 /// XM_005250518 /// XM_006716073 /// XM_006716074 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction 202007_at BF940043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF940043 /FEA=EST /DB_XREF=gi:12357363 /DB_XREF=est:nac66f12.x1 /CLONE=IMAGE:3439271 /UG=Hs.62041 nidogen (enactin) /FL=gb:M30269.1 gb:NM_002508.1 BF940043 nidogen 1 NID1 4811 NM_002508 /// XM_006711771 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from electronic annotation /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202008_s_at NM_002508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002508.1 /DEF=Homo sapiens nidogen (enactin) (NID), mRNA. /FEA=mRNA /GEN=NID /PROD=nidogen (enactin) /DB_XREF=gi:4505394 /UG=Hs.62041 nidogen (enactin) /FL=gb:M30269.1 gb:NM_002508.1 NM_002508 nidogen 1 NID1 4811 NM_002508 /// XM_006711771 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from electronic annotation /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202009_at NM_007284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007284.1 /DEF=Homo sapiens protein tyrosine kinase 9-like (A6-related protein) (PTK9L), mRNA. /FEA=mRNA /GEN=PTK9L /PROD=protein tyrosine kinase 9-like (A6-relatedprotein) /DB_XREF=gi:6005845 /UG=Hs.6780 protein tyrosine kinase 9-like (A6-related protein) /FL=gb:BC000327.1 gb:BC003161.1 gb:NM_007284.1 gb:AL136773.1 NM_007284 twinfilin actin-binding protein 2 TWF2 11344 NM_007284 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0032532 // regulation of microvillus length // inferred by curator /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from mutant phenotype /// 0051016 // barbed-end actin filament capping // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from direct assay /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 202010_s_at NM_021188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021188.1 /DEF=Homo sapiens clones 23667 and 23775 zinc finger protein (LOC57862), mRNA. /FEA=mRNA /GEN=LOC57862 /PROD=clones 23667 and 23775 zinc finger protein /DB_XREF=gi:10863994 /UG=Hs.7137 clones 23667 and 23775 zinc finger protein /FL=gb:NM_021188.1 gb:U90919.1 NM_021188 prostaglandin reductase 2 /// zinc finger protein 410 PTGR2 /// ZNF410 57862 /// 145482 NM_001146154 /// NM_001146155 /// NM_001242924 /// NM_001242926 /// NM_001242927 /// NM_001242928 /// NM_021188 /// NM_152444 /// NR_040251 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0036132 // 13-prostaglandin reductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047522 // 15-oxoprostaglandin 13-oxidase activity // inferred from direct assay 202011_at NM_003257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003257.1 /DEF=Homo sapiens tight junction protein 1 (zona occludens 1) (TJP1), mRNA. /FEA=mRNA /GEN=TJP1 /PROD=tight junction protein 1 (zona occludens 1) /DB_XREF=gi:4507516 /UG=Hs.74614 tight junction protein 1 (zona occludens 1) /FL=gb:L14837.1 gb:NM_003257.1 NM_003257 tight junction protein 1 TJP1 7082 NM_003257 /// NM_175610 /// XM_005254616 /// XM_005254617 /// XM_005254618 /// XM_005254619 /// XM_005254620 /// XM_005254621 /// XM_006720660 /// XM_006720661 /// XM_006725553 /// XM_006725554 /// XM_006725555 /// XM_006725556 /// XM_006725557 /// XM_006725558 /// XM_006725559 /// XM_006725560 0001825 // blastocyst formation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0071000 // response to magnetism // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1901350 // cell-cell signaling involved in cell-cell junction organization // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043296 // apical junction complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0046581 // intercellular canaliculus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 202012_s_at AA196245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA196245 /FEA=EST /DB_XREF=gi:1791879 /DB_XREF=est:zp92h05.s1 /CLONE=IMAGE:627705 /UG=Hs.75334 exostoses (multiple) 2 /FL=gb:U64511.1 gb:NM_000401.1 AA196245 exostosin glycosyltransferase 2 EXT2 2132 NM_000401 /// NM_001178083 /// NM_207122 0001503 // ossification // inferred from mutant phenotype /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement 202013_s_at NM_000401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000401.1 /DEF=Homo sapiens exostoses (multiple) 2 (EXT2), mRNA. /FEA=mRNA /GEN=EXT2 /PROD=exostoses (multiple) 2 /DB_XREF=gi:4557572 /UG=Hs.75334 exostoses (multiple) 2 /FL=gb:U64511.1 gb:NM_000401.1 NM_000401 exostosin glycosyltransferase 2 EXT2 2132 NM_000401 /// NM_001178083 /// NM_207122 0001503 // ossification // inferred from mutant phenotype /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement 202014_at NM_014330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014330.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible 34 (GADD34), mRNA. /FEA=mRNA /GEN=GADD34 /PROD=growth arrest and DNA-damage-inducible 34 /DB_XREF=gi:9790902 /UG=Hs.76556 growth arrest and DNA-damage-inducible 34 /FL=gb:BC003067.1 gb:U83981.1 gb:NM_014330.2 NM_014330 protein phosphatase 1, regulatory subunit 15A PPP1R15A 23645 NM_014330 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 202015_x_at NM_006838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006838.1 /DEF=Homo sapiens methionine aminopeptidase; eIF-2-associated p67 (MNPEP), mRNA. /FEA=mRNA /GEN=MNPEP /PROD=methionine aminopeptidase; eIF-2-associated p67 /DB_XREF=gi:5803091 /UG=Hs.78935 methionine aminopeptidase; eIF-2-associated p67 /FL=gb:NM_006838.1 gb:U29607.1 NM_006838 0006508 // proteolysis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031365 // N-terminal protein amino acid modification // inferred from direct assay /// 0070084 // protein initiator methionine removal // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from electronic annotation 202016_at NM_002402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002402.1 /DEF=Homo sapiens mesoderm specific transcript (mouse) homolog (MEST), mRNA. /FEA=mRNA /GEN=MEST /PROD=mesoderm specific transcript (mouse) homolog /DB_XREF=gi:4505154 /UG=Hs.79284 mesoderm specific transcript (mouse) homolog /FL=gb:BC002413.1 gb:D78611.1 gb:D87367.1 gb:NM_002402.1 NM_002402 mesoderm specific transcript MEST 4232 NM_001253900 /// NM_001253901 /// NM_001253902 /// NM_002402 /// NM_177524 /// NM_177525 0007498 // mesoderm development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010883 // regulation of lipid storage // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202017_at NM_000120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000120.2 /DEF=Homo sapiens epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), mRNA. /FEA=mRNA /GEN=EPHX1 /PROD=epoxide hydrolase 1, microsomal (xenobiotic) /DB_XREF=gi:4557560 /UG=Hs.89649 epoxide hydrolase 1, microsomal (xenobiotic) /FL=gb:BC003567.1 gb:J03518.1 gb:L25878.1 gb:L25879.1 gb:NM_000120.2 NM_000120 epoxide hydrolase 1, microsomal (xenobiotic) EPHX1 2052 NM_000120 /// NM_001136018 /// NM_001291163 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004301 // epoxide hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033961 // cis-stilbene-oxide hydrolase activity // inferred from electronic annotation 202018_s_at NM_002343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002343.1 /DEF=Homo sapiens lactotransferrin (LTF), mRNA. /FEA=mRNA /GEN=LTF /PROD=lactotransferrin /DB_XREF=gi:4505042 /UG=Hs.105938 lactotransferrin /FL=gb:AF332168.1 gb:M93150.1 gb:M83202.1 gb:NM_002343.1 NM_002343 lactotransferrin LTF 4057 NM_001199149 /// NM_002343 0001503 // ossification // inferred from electronic annotation /// 0001817 // regulation of cytokine production // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0019732 // antifungal humoral response // inferred from direct assay /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0033214 // iron assimilation by chelation and transport // traceable author statement /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051701 // interaction with host // traceable author statement /// 0052572 // response to host immune response // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090382 // phagosome maturation // traceable author statement /// 1900159 // positive regulation of bone mineralization involved in bone maturation // inferred from sequence or structural similarity /// 1900229 // negative regulation of single-species biofilm formation in or on host organism // inferred from direct assay /// 1902732 // positive regulation of chondrocyte proliferation // inferred from direct assay /// 2000308 // negative regulation of tumor necrosis factor (ligand) superfamily member 11 production // inferred from sequence or structural similarity /// 2001205 // negative regulation of osteoclast development // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097013 // phagocytic vesicle lumen // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202019_s_at AI935255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935255 /FEA=EST /DB_XREF=gi:5674125 /DB_XREF=est:wp16a02.x1 /CLONE=IMAGE:2464970 /UG=Hs.13351 LanC (bacterial lantibiotic synthetase component C)-like 1 /FL=gb:NM_006055.1 AI935255 LanC lantibiotic synthetase component C-like 1 (bacterial) LANCL1 10314 NM_001136574 /// NM_001136575 /// NM_006055 /// XM_005246243 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 202020_s_at NM_006055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006055.1 /DEF=Homo sapiens LanC (bacterial lantibiotic synthetase component C)-like 1 (LANCL1), mRNA. /FEA=mRNA /GEN=LANCL1 /PROD=lanthionine synthetase C-like protein 1 /DB_XREF=gi:5174444 /UG=Hs.13351 LanC (bacterial lantibiotic synthetase component C)-like 1 /FL=gb:NM_006055.1 NM_006055 LanC lantibiotic synthetase component C-like 1 (bacterial) LANCL1 10314 NM_001136574 /// NM_001136575 /// NM_006055 /// XM_005246243 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 202021_x_at AF083441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083441.1 /DEF=Homo sapiens SUI1 isolog mRNA, complete cds. /FEA=mRNA /PROD=SUI1 isolog /DB_XREF=gi:5813822 /UG=Hs.150580 putative translation initiation factor /FL=gb:BC005118.1 gb:AF100737.1 gb:L26247.1 gb:NM_005801.1 gb:AF083441.1 AF083441 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202022_at NM_005165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005165.1 /DEF=Homo sapiens aldolase C, fructose-bisphosphate (ALDOC), mRNA. /FEA=mRNA /GEN=ALDOC /PROD=aldolase C, fructose-bisphosphate /DB_XREF=gi:4885062 /UG=Hs.155247 aldolase C, fructose-bisphosphate /FL=gb:BC003613.1 gb:AF054987.1 gb:NM_005165.1 NM_005165 aldolase C, fructose-bisphosphate ALDOC 230 NM_005165 /// XM_005257947 /// XM_005257949 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred by curator /// 0030424 // axon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation 202023_at NM_004428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004428.1 /DEF=Homo sapiens ephrin-A1 (EFNA1), mRNA. /FEA=mRNA /GEN=EFNA1 /PROD=ephrin A1 precursor /DB_XREF=gi:4758245 /UG=Hs.1624 ephrin-A1 /FL=gb:M57730.1 gb:NM_004428.1 NM_004428 ephrin-A1 EFNA1 1942 NM_004428 /// NM_182685 /// XM_005244940 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // not recorded /// 0003180 // aortic valve morphogenesis // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // not recorded /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0014028 // notochord formation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202024_at NM_004317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004317.1 /DEF=Homo sapiens arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 (ASNA1), mRNA. /FEA=mRNA /GEN=ASNA1 /PROD=arsA (bacterial) arsenite transporter,ATP-binding, homolog 1 /DB_XREF=gi:4757795 /UG=Hs.165439 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 /FL=gb:BC002651.1 gb:U60276.1 gb:AF047469.1 gb:NM_004317.1 NM_004317 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) ASNA1 439 NM_004317 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015698 // inorganic anion transport // traceable author statement /// 0045048 // protein insertion into ER membrane // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015105 // arsenite transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202025_x_at NM_001607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001607.2 /DEF=Homo sapiens acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) (ACAA1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACAA1 /PROD=acetyl-Coenzyme A acyltransferase 1 /DB_XREF=gi:6598316 /UG=Hs.166160 acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC000635.1 gb:NM_001607.2 NM_001607 acetyl-CoA acyltransferase 1 ACAA1 30 NM_001130410 /// NM_001607 /// NR_024024 /// XM_006713122 /// XM_006713123 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from mutant phenotype /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016401 // palmitoyl-CoA oxidase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 202026_at NM_003002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003002.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHD /PROD=succinate dehydrogenase complex, subunit Dprecursor /DB_XREF=gi:4506864 /UG=Hs.168289 succinate dehydrogenase complex, subunit D, integral membrane protein /FL=gb:BC005263.1 gb:AB006202.1 gb:NM_003002.1 NM_003002 succinate dehydrogenase complex, subunit D, integral membrane protein SDHD 6392 NM_001276503 /// NM_001276504 /// NM_001276506 /// NM_003002 /// NR_077060 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity 202027_at NM_012264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012264.1 /DEF=Homo sapiens chromosome 22 open reading frame 5 (C22ORF5), mRNA. /FEA=mRNA /GEN=C22ORF5 /PROD=chromosome 22 open reading frame 5 /DB_XREF=gi:7110634 /UG=Hs.182626 chromosome 22 open reading frame 5 /FL=gb:NM_012264.1 NM_012264 transmembrane protein 184B TMEM184B 25829 NM_001195071 /// NM_001195072 /// NM_012264 /// XM_005261509 /// XM_005261510 /// XM_005261511 /// XM_005261512 /// XM_005261513 /// XM_005261514 /// XM_006724227 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202028_s_at BC000603 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000603.1 /DEF=Homo sapiens, ribosomal protein L38, clone MGC:1637, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L38 /DB_XREF=gi:12653644 /UG=Hs.2017 ribosomal protein L38 /FL=gb:BC000603.1 gb:NM_000999.1 BC000603 ribosomal protein L38 RPL38 6169 NM_000999 /// NM_001035258 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034463 // 90S preribosome assembly // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048318 // axial mesoderm development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033291 // eukaryotic 80S initiation complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 202029_x_at NM_000999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000999.1 /DEF=Homo sapiens ribosomal protein L38 (RPL38), mRNA. /FEA=mRNA /GEN=RPL38 /PROD=ribosomal protein L38 /DB_XREF=gi:4506644 /UG=Hs.2017 ribosomal protein L38 /FL=gb:BC000603.1 gb:NM_000999.1 NM_000999 ribosomal protein L38 RPL38 6169 NM_000999 /// NM_001035258 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034463 // 90S preribosome assembly // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048318 // axial mesoderm development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033291 // eukaryotic 80S initiation complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 202030_at NM_005881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005881.1 /DEF=Homo sapiens branched chain alpha-ketoacid dehydrogenase kinase (BCKDK), mRNA. /FEA=mRNA /GEN=BCKDK /PROD=branched chain alpha-ketoacid dehydrogenasekinase /DB_XREF=gi:5031608 /UG=Hs.20644 branched chain alpha-ketoacid dehydrogenase kinase /FL=gb:AF026548.1 gb:NM_005881.1 NM_005881 branched chain ketoacid dehydrogenase kinase BCKDK 10295 NM_001122957 /// NM_001271926 /// NM_005881 0006468 // protein phosphorylation // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // non-traceable author statement /// 0009083 // branched-chain amino acid catabolic process // inferred from sequence or structural similarity /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from sequence or structural similarity /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047323 // [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity // inferred from electronic annotation 202031_s_at NM_015610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015610.1 /DEF=Homo sapiens DKFZP434J154 protein (DKFZP434J154), mRNA. /FEA=mRNA /GEN=DKFZP434J154 /PROD=DKFZP434J154 protein /DB_XREF=gi:7661579 /UG=Hs.226372 DKFZP434J154 protein /FL=gb:BC004116.1 gb:AL080155.1 gb:NM_015610.1 NM_015610 WD repeat domain, phosphoinositide interacting 2 WIPI2 26100 NM_001033518 /// NM_001033519 /// NM_001033520 /// NM_001278299 /// NM_015610 /// NM_016003 /// XM_006715685 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000421 // autophagic vacuole membrane // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 202032_s_at NM_006122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006122.1 /DEF=Homo sapiens mannosidase, alpha, class 2A, member 2 (MAN2A2), mRNA. /FEA=mRNA /GEN=MAN2A2 /PROD=mannosidase, alpha, class 2A, member 2 /DB_XREF=gi:5540099 /UG=Hs.295605 mannosidase, alpha, class 2A, member 2 /FL=gb:NM_006122.1 gb:L28821.1 NM_006122 mannosidase, alpha, class 2A, member 2 MAN2A2 4122 NM_006122 /// XM_005254910 /// XM_005254911 /// XM_006720507 /// XR_243208 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0004572 // mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202033_s_at BG402105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG402105 /FEA=EST /DB_XREF=gi:13295553 /DB_XREF=est:602465641F1 /CLONE=IMAGE:4593682 /UG=Hs.50421 KIAA0203 gene product /FL=gb:D86958.1 gb:NM_014781.1 BG402105 RB1-inducible coiled-coil 1 RB1CC1 9821 NM_001083617 /// NM_014781 /// XM_006716491 /// XM_006716492 /// XM_006716493 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202034_x_at NM_014781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014781.1 /DEF=Homo sapiens KIAA0203 gene product (KIAA0203), mRNA. /FEA=mRNA /GEN=KIAA0203 /PROD=KIAA0203 gene product /DB_XREF=gi:7661991 /UG=Hs.50421 KIAA0203 gene product /FL=gb:D86958.1 gb:NM_014781.1 NM_014781 RB1-inducible coiled-coil 1 RB1CC1 9821 NM_001083617 /// NM_014781 /// XM_006716491 /// XM_006716492 /// XM_006716493 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202035_s_at AI332407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI332407 /FEA=EST /DB_XREF=gi:4068966 /DB_XREF=est:qq15g12.x1 /CLONE=IMAGE:1932646 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2 AI332407 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202036_s_at AF017987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF017987.1 /DEF=Homo sapiens secreted apoptosis related protein 2 (SARP2) mRNA, complete cds. /FEA=mRNA /GEN=SARP2 /PROD=secreted apoptosis related protein 2 /DB_XREF=gi:2415416 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2 AF017987 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202037_s_at NM_003012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003012.2 /DEF=Homo sapiens secreted frizzled-related protein 1 (SFRP1), mRNA. /FEA=mRNA /GEN=SFRP1 /PROD=secreted frizzled-related protein 1 /DB_XREF=gi:8400731 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2 NM_003012 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202038_at NM_004788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004788.1 /DEF=Homo sapiens ubiquitination factor E4A (homologous to yeast UFD2) (UBE4A), mRNA. /FEA=mRNA /GEN=UBE4A /PROD=ubiquitination factor E4A (homologous to yeastUFD2) /DB_XREF=gi:4759287 /UG=Hs.75275 ubiquitination factor E4A (homologous to yeast UFD2) /FL=gb:D50916.1 gb:NM_004788.1 NM_004788 ubiquitination factor E4A UBE4A 9354 NM_001204077 /// NM_004788 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202039_at NM_004740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004740.1 /DEF=Homo sapiens TGFB1-induced anti-apoptotic factor 1 (TIAF1), mRNA. /FEA=mRNA /GEN=TIAF1 /PROD=TGFB1-induced anti-apoptotic factor 1 /DB_XREF=gi:4759231 /UG=Hs.75822 TGFB1-induced anti-apoptotic factor 1 /FL=gb:D86970.1 gb:AF105277.1 gb:NM_004740.1 NM_004740 myosin XVIIIA /// TGFB1-induced anti-apoptotic factor 1 MYO18A /// TIAF1 9220 /// 399687 NM_004740 /// NM_078471 /// NM_203318 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0048194 // Golgi vesicle budding // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0042641 // actomyosin // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 202040_s_at NM_005056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005056.1 /DEF=Homo sapiens retinoblastoma-binding protein 2 (RBBP2), mRNA. /FEA=mRNA /GEN=RBBP2 /PROD=retinoblastoma-binding protein 2 /DB_XREF=gi:4826967 /UG=Hs.76272 retinoblastoma-binding protein 2 /FL=gb:NM_005056.1 NM_005056 lysine (K)-specific demethylase 5A KDM5A 5927 NM_001042603 /// NM_005056 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 202041_s_at NM_004214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004214.3 /DEF=Homo sapiens fibroblast growth factor (acidic) intracellular binding protein (FIBP), mRNA. /FEA=mRNA /GEN=FIBP /PROD=fibroblast growth factor (acidic) intracellularbinding protein /DB_XREF=gi:7262377 /UG=Hs.7768 fibroblast growth factor (acidic) intracellular binding protein /FL=gb:AF171944.1 gb:AF171945.1 gb:AF171946.1 gb:AF010187.2 gb:NM_004214.3 NM_004214 fibroblast growth factor (acidic) intracellular binding protein FIBP 9158 NM_004214 /// NM_198897 /// XM_005274391 /// XM_005274392 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0017134 // fibroblast growth factor binding // inferred from physical interaction 202042_at NM_002109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002109.2 /DEF=Homo sapiens histidyl-tRNA synthetase (HARS), mRNA. /FEA=mRNA /GEN=HARS /PROD=histidyl tRNA synthetase /DB_XREF=gi:6996013 /UG=Hs.77798 histidyl-tRNA synthetase /FL=gb:NM_002109.2 NM_002109 histidyl-tRNA synthetase /// uncharacterized LOC101928623 HARS /// LOC101928623 3035 /// 101928623 NM_001258040 /// NM_001258041 /// NM_001258042 /// NM_001289092 /// NM_001289093 /// NM_001289094 /// NM_002109 /// XM_005268428 /// XR_242729 /// XR_242730 /// XR_247486 /// XR_252702 /// XR_252703 /// XR_424088 /// XR_424089 /// XR_424090 /// XR_428675 /// XR_432546 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006427 // histidyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004821 // histidine-tRNA ligase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202043_s_at NM_004595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004595.1 /DEF=Homo sapiens spermine synthase (SMS), mRNA. /FEA=mRNA /GEN=SMS /PROD=spermine synthase /DB_XREF=gi:4759151 /UG=Hs.89718 spermine synthase /FL=gb:AD001528.1 gb:NM_004595.1 NM_004595 spermine synthase SMS 6611 NM_001258423 /// NM_004595 /// XM_005274582 /// XM_005274583 0006555 // methionine metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004766 // spermidine synthase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016768 // spermine synthase activity // inferred from electronic annotation 202044_at AU159484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159484 /FEA=EST /DB_XREF=gi:11021005 /DB_XREF=est:AU159484 /CLONE=THYRO1001796 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1 AU159484 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202045_s_at AI670100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI670100 /FEA=EST /DB_XREF=gi:4834874 /DB_XREF=est:wc11g10.x1 /CLONE=IMAGE:2314914 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1 AI670100 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202046_s_at NM_004491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004491.1 /DEF=Homo sapiens glucocorticoid receptor DNA binding factor 1 (GRLF1), mRNA. /FEA=mRNA /GEN=GRLF1 /PROD=glucocorticoid receptor DNA binding factor 1 /DB_XREF=gi:4758481 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1 NM_004491 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202047_s_at AI458128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI458128 /FEA=EST /DB_XREF=gi:4312134 /DB_XREF=est:tj64g03.x1 /CLONE=IMAGE:2146324 /UG=Hs.107374 chromobox homolog 6 /FL=gb:NM_014292.1 AI458128 chromobox homolog 6 CBX6 23466 NM_014292 /// XM_005261412 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202048_s_at NM_014292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014292.1 /DEF=Homo sapiens chromobox homolog 6 (CBX6), mRNA. /FEA=mRNA /GEN=CBX6 /PROD=chromobox homolog 6 /DB_XREF=gi:10140848 /UG=Hs.107374 chromobox homolog 6 /FL=gb:NM_014292.1 NM_014292 chromobox homolog 6 CBX6 23466 NM_014292 /// XM_005261412 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202049_s_at AA521508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521508 /FEA=EST /DB_XREF=gi:2262051 /DB_XREF=est:aa74h06.s1 /CLONE=IMAGE:826715 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1 AA521508 zinc finger, MYM-type 4 ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202050_s_at AI650586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI650586 /FEA=EST /DB_XREF=gi:4734565 /DB_XREF=est:wa92g09.x1 /CLONE=IMAGE:2303680 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1 AI650586 zinc finger, MYM-type 4 ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202051_s_at NM_005095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005095.1 /DEF=Homo sapiens zinc finger protein 262 (ZNF262), mRNA. /FEA=mRNA /GEN=ZNF262 /PROD=zinc finger protein 262 /DB_XREF=gi:4827068 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1 NM_005095 zinc finger, MYM-type 4 ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202052_s_at NM_015577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015577.1 /DEF=Homo sapiens novel retinal pigment epithelial gene (NORPEG), mRNA. /FEA=mRNA /GEN=NORPEG /PROD=DKFZP564G013 protein /DB_XREF=gi:13470085 /UG=Hs.15165 novel retinal pigment epithelial gene /FL=gb:NM_015577.1 gb:AF155135.1 NM_015577 retinoic acid induced 14 RAI14 26064 NM_001145520 /// NM_001145521 /// NM_001145522 /// NM_001145523 /// NM_001145525 /// NM_015577 /// XM_006714469 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 202053_s_at L47162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L47162.1 /DEF=Human fatty aldehyde dehydrogenase (FALDH) mRNA, complete cds. /FEA=mRNA /GEN=FALDH /PROD=fatty aldehyde dehydrogenase /DB_XREF=gi:1082035 /UG=Hs.159608 aldehyde dehydrogenase 3 family, member A2 /FL=gb:L47162.1 gb:U46689.1 gb:NM_000382.1 L47162 aldehyde dehydrogenase 3 family, member A2 ALDH3A2 224 NM_000382 /// NM_001031806 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0006081 // cellular aldehyde metabolic process // non-traceable author statement /// 0006714 // sesquiterpenoid metabolic process // inferred from direct assay /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007422 // peripheral nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0033306 // phytol metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from mutant phenotype /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046577 // long-chain-alcohol oxidase activity // inferred from direct assay /// 0050061 // long-chain-aldehyde dehydrogenase activity // inferred from direct assay /// 0052814 // medium-chain-aldehyde dehydrogenase activity // inferred from direct assay 202054_s_at NM_000382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000382.1 /DEF=Homo sapiens aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), mRNA. /FEA=mRNA /GEN=ALDH3A2 /PROD=aldehyde dehydrogenase 3A2 /DB_XREF=gi:4557302 /UG=Hs.159608 aldehyde dehydrogenase 3 family, member A2 /FL=gb:L47162.1 gb:U46689.1 gb:NM_000382.1 NM_000382 aldehyde dehydrogenase 3 family, member A2 ALDH3A2 224 NM_000382 /// NM_001031806 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0006081 // cellular aldehyde metabolic process // non-traceable author statement /// 0006714 // sesquiterpenoid metabolic process // inferred from direct assay /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007422 // peripheral nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0033306 // phytol metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from mutant phenotype /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046577 // long-chain-alcohol oxidase activity // inferred from direct assay /// 0050061 // long-chain-aldehyde dehydrogenase activity // inferred from direct assay /// 0052814 // medium-chain-aldehyde dehydrogenase activity // inferred from direct assay 202055_at AA652173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA652173 /FEA=EST /DB_XREF=gi:2583825 /DB_XREF=est:ns51f05.s1 /CLONE=IMAGE:1187169 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 AA652173 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202056_at AW051311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW051311 /FEA=EST /DB_XREF=gi:5913581 /DB_XREF=est:wy89b01.x1 /CLONE=IMAGE:2555689 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 AW051311 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202057_at BC002374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002374.1 /DEF=Homo sapiens, karyopherin alpha 1 (importin alpha 5), clone MGC:8554, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin alpha 1 (importin alpha 5) /DB_XREF=gi:12803140 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 BC002374 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202058_s_at BC002374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002374.1 /DEF=Homo sapiens, karyopherin alpha 1 (importin alpha 5), clone MGC:8554, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin alpha 1 (importin alpha 5) /DB_XREF=gi:12803140 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 BC002374 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202059_s_at NM_002264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002264.1 /DEF=Homo sapiens karyopherin alpha 1 (importin alpha 5) (KPNA1), mRNA. /FEA=mRNA /GEN=KPNA1 /PROD=karyopherin alpha 1 /DB_XREF=gi:4504894 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 NM_002264 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202060_at NM_014633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014633.1 /DEF=Homo sapiens KIAA0155 gene product (KIAA0155), mRNA. /FEA=mRNA /GEN=KIAA0155 /PROD=KIAA0155 gene product /DB_XREF=gi:7661949 /UG=Hs.173288 KIAA0155 gene product /FL=gb:NM_014633.1 gb:D63875.1 NM_014633 CTR9, Paf1/RNA polymerase II complex component CTR9 9646 NM_014633 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070102 // interleukin-6-mediated signaling pathway // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 2001162 // positive regulation of histone H3-K79 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035327 // transcriptionally active chromatin // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from electronic annotation 202061_s_at AI927770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927770 /FEA=EST /DB_XREF=gi:5663734 /DB_XREF=est:wo08h07.x1 /CLONE=IMAGE:2454781 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1 AI927770 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202062_s_at NM_005065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005065.1 /DEF=Homo sapiens sel-1 (suppressor of lin-12, C.elegans)-like (SEL1L), mRNA. /FEA=mRNA /GEN=SEL1L /PROD=sel-1 (suppressor of lin-12, C.elegans)-like /DB_XREF=gi:4826995 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1 NM_005065 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202063_s_at AB020335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020335.1 /DEF=Homo sapiens Pancreas-specific TSA305 mRNA , complete cds. /FEA=mRNA /GEN=TSA305 /DB_XREF=gi:6518494 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1 AB020335 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202064_s_at AF052059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF052059.1 /DEF=Homo sapiens SEL1L (SEL1L) mRNA, complete cds. /FEA=mRNA /GEN=SEL1L /PROD=SEL1L /DB_XREF=gi:6851088 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1 AF052059 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202065_s_at BG033593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG033593 /FEA=EST /DB_XREF=gi:12426042 /DB_XREF=est:602301717F1 /CLONE=IMAGE:4403212 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:NM_003626.1 gb:U22816.1 BG033593 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202066_at AA195259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA195259 /FEA=EST /DB_XREF=gi:1784959 /DB_XREF=est:zr36g01.s1 /CLONE=IMAGE:665520 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:NM_003626.1 gb:U22816.1 AA195259 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202067_s_at AI861942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI861942 /FEA=EST /DB_XREF=gi:5526049 /DB_XREF=est:td18b10.x1 /CLONE=IMAGE:2075995 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) /FL=gb:NM_000527.2 AI861942 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 202068_s_at NM_000527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000527.2 /DEF=Homo sapiens low density lipoprotein receptor (familial hypercholesterolemia) (LDLR), mRNA. /FEA=mRNA /GEN=LDLR /PROD=low density lipoprotein receptor precursor /DB_XREF=gi:8051613 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) /FL=gb:NM_000527.2 NM_000527 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 202069_s_at AI826060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI826060 /FEA=EST /DB_XREF=gi:5446731 /DB_XREF=est:wk28a12.x1 /CLONE=IMAGE:2413630 /UG=Hs.250616 isocitrate dehydrogenase 3 (NAD+) alpha /FL=gb:NM_005530.1 gb:U07681.1 AI826060 isocitrate dehydrogenase 3 (NAD+) alpha IDH3A 3419 NM_005530 /// XM_005254334 /// XM_005254336 /// XM_005254337 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 202070_s_at NM_005530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005530.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A), mRNA. /FEA=mRNA /GEN=IDH3A /PROD=isocitrate dehydrogenase 3 (NAD+) alpha /DB_XREF=gi:5031776 /UG=Hs.250616 isocitrate dehydrogenase 3 (NAD+) alpha /FL=gb:NM_005530.1 gb:U07681.1 NM_005530 isocitrate dehydrogenase 3 (NAD+) alpha IDH3A 3419 NM_005530 /// XM_005254334 /// XM_005254336 /// XM_005254337 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 202071_at NM_002999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002999.1 /DEF=Homo sapiens syndecan 4 (amphiglycan, ryudocan) (SDC4), mRNA. /FEA=mRNA /GEN=SDC4 /PROD=syndecan 4 (amphiglycan, ryudocan) /DB_XREF=gi:4506860 /UG=Hs.252189 syndecan 4 (amphiglycan, ryudocan) /FL=gb:NM_002999.1 NM_002999 syndecan 4 SDC4 6385 NM_002999 0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0070053 // thrombospondin receptor activity // inferred from mutant phenotype 202072_at NM_001533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001533.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein L (HNRPL), mRNA. /FEA=mRNA /GEN=HNRPL /PROD=heterogeneous nuclear ribonucleoprotein L /DB_XREF=gi:4557644 /UG=Hs.2730 heterogeneous nuclear ribonucleoprotein L /FL=gb:AB044547.1 gb:NM_001533.1 NM_001533 heterogeneous nuclear ribonucleoprotein L HNRNPL 3191 NM_001005335 /// NM_001533 /// XR_243927 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202073_at AV757675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV757675 /FEA=EST /DB_XREF=gi:10915523 /DB_XREF=est:AV757675 /CLONE=BMFAVB12 /UG=Hs.278898 tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein /FL=gb:NM_021980.1 AV757675 optineurin OPTN 10133 NM_001008211 /// NM_001008212 /// NM_001008213 /// NM_021980 /// XM_005252336 /// XM_005252337 /// XM_005252338 0000042 // protein targeting to Golgi // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001920 // negative regulation of receptor recycling // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016236 // macroautophagy // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 202074_s_at NM_021980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021980.1 /DEF=Homo sapiens tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein (FIP2), mRNA. /FEA=mRNA /GEN=FIP2 /PROD=tumor necrosis factor alpha-inducible cellularprotein containing leucine zipper domains; Huntingtininteracting protein L; transcrption factorIIIA-interacting protein /DB_XREF=gi:11415041 /UG=Hs.278898 tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein /FL=gb:NM_021980.1 NM_021980 optineurin OPTN 10133 NM_001008211 /// NM_001008212 /// NM_001008213 /// NM_021980 /// XM_005252336 /// XM_005252337 /// XM_005252338 0000042 // protein targeting to Golgi // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001920 // negative regulation of receptor recycling // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016236 // macroautophagy // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 202075_s_at NM_006227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006227.1 /DEF=Homo sapiens phospholipid transfer protein (PLTP), mRNA. /FEA=mRNA /GEN=PLTP /PROD=phospholipid transfer protein /DB_XREF=gi:5453913 /UG=Hs.283007 phospholipid transfer protein /FL=gb:L26232.1 gb:NM_006227.1 NM_006227 phospholipid transfer protein PLTP 5360 NM_001242920 /// NM_001242921 /// NM_006227 /// NM_182676 /// XM_005260439 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0010189 // vitamin E biosynthetic process // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 202076_at NM_001166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001166.2 /DEF=Homo sapiens baculoviral IAP repeat-containing 2 (BIRC2), mRNA. /FEA=mRNA /GEN=BIRC2 /PROD=baculoviral IAP repeat-containing protein 2 /DB_XREF=gi:10880127 /UG=Hs.289107 baculoviral IAP repeat-containing 2 /FL=gb:NM_001166.2 gb:U37547.1 gb:L49431.1 gb:U45879.1 NM_001166 baculoviral IAP repeat containing 2 BIRC2 329 NM_001166 /// NM_001256163 /// NM_001256166 0000209 // protein polyubiquitination // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034121 // regulation of toll-like receptor signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0039535 // regulation of RIG-I signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045088 // regulation of innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060544 // regulation of necroptotic process // inferred from mutant phenotype /// 0070266 // necroptotic process // inferred from electronic annotation /// 0070424 // regulation of nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 1902523 // positive regulation of protein K63-linked ubiquitination // inferred from direct assay /// 1902524 // positive regulation of protein K48-linked ubiquitination // inferred from direct assay /// 1902527 // positive regulation of protein monoubiquitination // inferred from direct assay /// 2000116 // regulation of cysteine-type endopeptidase activity // traceable author statement 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 202077_at NM_005003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005003.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1, alphabeta subcomplex, 1 (8kD, SDAP) (NDUFAB1), mRNA. /FEA=mRNA /GEN=NDUFAB1 /PROD=NADH dehydrogenase (ubiquinone) 1, alphabetasubcomplex, 1 (8kD, SDAP) /DB_XREF=gi:4826851 /UG=Hs.5556 NADH dehydrogenase (ubiquinone) 1, alphabeta subcomplex, 1 (8kD, SDAP) /FL=gb:AF087660.1 gb:NM_005003.1 NM_005003 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa NDUFAB1 4706 NM_005003 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // non-traceable author statement /// 0009249 // protein lipoylation // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from sequence or structural similarity /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // non-traceable author statement /// 0070469 // respiratory chain // inferred from electronic annotation 0000036 // ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process // non-traceable author statement /// 0005504 // fatty acid binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202078_at NM_003653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003653.1 /DEF=Homo sapiens COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3 (COPS3), mRNA. /FEA=mRNA /GEN=COPS3 /PROD=COP9 (constitutive photomorphogenic,Arabidopsis, homolog) subunit 3 /DB_XREF=gi:4502974 /UG=Hs.6076 COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3 /FL=gb:BC001891.1 gb:AF031647.1 gb:NM_003653.1 gb:AF098109.1 NM_003653 COP9 signalosome subunit 3 COPS3 8533 NM_001199125 /// NM_003653 /// XM_005256837 /// XM_005256838 /// XM_005256839 /// XM_005256840 /// XM_005256841 /// XM_005256842 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0009416 // response to light stimulus // traceable author statement /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202079_s_at AI633774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633774 /FEA=EST /DB_XREF=gi:4685104 /DB_XREF=est:tt28d06.x1 /CLONE=IMAGE:2242091 /UG=Hs.6705 KIAA1042 protein /FL=gb:AB028965.1 gb:NM_014965.1 AI633774 trafficking protein, kinesin binding 1 TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 202080_s_at NM_014965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014965.1 /DEF=Homo sapiens KIAA1042 protein (KIAA1042), mRNA. /FEA=mRNA /GEN=KIAA1042 /PROD=KIAA1042 protein /DB_XREF=gi:7662457 /UG=Hs.6705 KIAA1042 protein /FL=gb:AB028965.1 gb:NM_014965.1 NM_014965 trafficking protein, kinesin binding 1 TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 202081_at NM_004907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004907.1 /DEF=Homo sapiens immediate early protein (ETR101), mRNA. /FEA=mRNA /GEN=ETR101 /PROD=immediate early protein /DB_XREF=gi:4758313 /UG=Hs.737 immediate early protein /FL=gb:BC003625.1 gb:M62831.1 gb:NM_004907.1 NM_004907 immediate early response 2 IER2 9592 NM_004907 0005737 // cytoplasm // inferred from electronic annotation 202082_s_at AV748469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV748469 /FEA=EST /DB_XREF=gi:10906317 /DB_XREF=est:AV748469 /CLONE=NPCAXA07 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1 AV748469 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202083_s_at AI017770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI017770 /FEA=EST /DB_XREF=gi:3232106 /DB_XREF=est:ov32b12.x1 /CLONE=IMAGE:1639007 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1 AI017770 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202084_s_at NM_003003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003003.1 /DEF=Homo sapiens SEC14 (S. cerevisiae)-like 1 (SEC14L1), mRNA. /FEA=mRNA /GEN=SEC14L1 /PROD=SEC14 (S. cerevisiae)-like 1 /DB_XREF=gi:4506866 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1 NM_003003 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202085_at NM_004817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004817.1 /DEF=Homo sapiens tight junction protein 2 (zona occludens 2) (TJP2), mRNA. /FEA=mRNA /GEN=TJP2 /PROD=tight junction protein 2 (zona occludens 2) /DB_XREF=gi:4759341 /UG=Hs.75608 tight junction protein 2 (zona occludens 2) /FL=gb:NM_004817.1 gb:L27476.1 NM_004817 tight junction protein 2 TJP2 9414 NM_001170414 /// NM_001170415 /// NM_001170416 /// NM_001170630 /// NM_004817 /// NM_201629 /// XM_005252311 /// XM_005252312 /// XM_005252313 /// XM_005252314 /// XM_005252315 /// XM_006717324 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation 202086_at NM_002462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002462.1 /DEF=Homo sapiens myxovirus (influenza) resistance 1, homolog of murine (interferon-inducible protein p78) (MX1), mRNA. /FEA=mRNA /GEN=MX1 /PROD=myxovirus (influenza) resistance 1, homolog ofmurine (interferon-inducible protein p78) /DB_XREF=gi:4505290 /UG=Hs.76391 myxovirus (influenza) resistance 1, homolog of murine (interferon-inducible protein p78) /FL=gb:M30817.1 gb:M33882.1 gb:NM_002462.1 NM_002462 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) MX1 4599 NM_001144925 /// NM_001178046 /// NM_001282920 /// NM_002462 /// XM_005260978 /// XM_005260979 /// XM_005260980 /// XM_005260981 /// XM_005260982 /// XM_006724005 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034340 // response to type I interferon // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 202087_s_at NM_001912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001912.1 /DEF=Homo sapiens cathepsin L (CTSL), mRNA. /FEA=mRNA /GEN=CTSL /PROD=cathepsin L /DB_XREF=gi:4503154 /UG=Hs.78056 cathepsin L /FL=gb:NM_001912.1 NM_001912 cathepsin L CTSL 1514 NM_001257971 /// NM_001257972 /// NM_001257973 /// NM_001912 /// NM_145918 /// XM_005251716 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0006508 // proteolysis // inferred from direct assay /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0071888 // macrophage apoptotic process // non-traceable author statement /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202088_at AI635449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI635449 /FEA=EST /DB_XREF=gi:4686779 /DB_XREF=est:ts65a01.x1 /CLONE=IMAGE:2233416 /UG=Hs.79136 LIV-1 protein, estrogen regulated /FL=gb:U41060.2 gb:NM_012319.2 AI635449 solute carrier family 39 (zinc transporter), member 6 SLC39A6 25800 NM_001099406 /// NM_012319 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype /// 0071578 // zinc ion transmembrane import // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202089_s_at NM_012319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012319.2 /DEF=Homo sapiens LIV-1 protein, estrogen regulated (LIV-1), mRNA. /FEA=mRNA /GEN=LIV-1 /PROD=LIV-1 protein, estrogen regulated /DB_XREF=gi:12751474 /UG=Hs.79136 LIV-1 protein, estrogen regulated /FL=gb:U41060.2 gb:NM_012319.2 NM_012319 solute carrier family 39 (zinc transporter), member 6 SLC39A6 25800 NM_001099406 /// NM_012319 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype /// 0071578 // zinc ion transmembrane import // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202090_s_at NM_006830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006830.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase (6.4kD) subunit (UQCR), mRNA. /FEA=mRNA /GEN=UQCR /PROD=ubiquinol-cytochrome c reductase (6.4kD)subunit /DB_XREF=gi:5803216 /UG=Hs.8372 ubiquinol-cytochrome c reductase (6.4kD) subunit /FL=gb:D55636.1 gb:NM_006830.1 NM_006830 ubiquinol-cytochrome c reductase, complex III subunit XI UQCR11 10975 NM_006830 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 202091_at BC003087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003087.1 /DEF=Homo sapiens, binder of Arl Two, clone MGC:1121, mRNA, complete cds. /FEA=mRNA /PROD=binder of Arl Two /DB_XREF=gi:13111840 /UG=Hs.9552 binder of Arl Two /FL=gb:BC003087.1 gb:AF126062.1 gb:NM_012106.1 BC003087 202092_s_at BF244411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF244411 /FEA=EST /DB_XREF=gi:11158342 /DB_XREF=est:601862994F1 /CLONE=IMAGE:4080550 /UG=Hs.9552 binder of Arl Two /FL=gb:BC003087.1 gb:AF126062.1 gb:NM_012106.1 BF244411 ADP-ribosylation factor-like 2 binding protein ARL2BP 23568 NM_012106 0007165 // signal transduction // traceable author statement /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051457 // maintenance of protein location in nucleus // inferred from mutant phenotype /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202093_s_at NM_019088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019088.1 /DEF=Homo sapiens hypothetical protein F23149_1 (F23149_1), mRNA. /FEA=mRNA /GEN=F23149_1 /PROD=hypothetical protein F23149_1 /DB_XREF=gi:9506582 /UG=Hs.152894 hypothetical protein F23149_1 /FL=gb:BC000017.1 gb:NM_019088.1 NM_019088 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) PAF1 54623 NM_001256826 /// NM_019088 /// NR_046384 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202094_at AA648913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA648913 /FEA=EST /DB_XREF=gi:2575342 /DB_XREF=est:ns41a09.s1 /CLONE=IMAGE:1186168 /UG=Hs.1578 baculoviral IAP repeat-containing 5 (survivin) /FL=gb:NM_001168.1 gb:AF077350.1 AA648913 baculoviral IAP repeat containing 5 BIRC5 332 NM_001012270 /// NM_001012271 /// NM_001168 /// XR_243654 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0050897 // cobalt ion binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction 202095_s_at NM_001168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001168.1 /DEF=Homo sapiens baculoviral IAP repeat-containing 5 (survivin) (BIRC5), mRNA. /FEA=mRNA /GEN=BIRC5 /PROD=baculoviral IAP repeat-containing protein 5 /DB_XREF=gi:4502144 /UG=Hs.1578 baculoviral IAP repeat-containing 5 (survivin) /FL=gb:NM_001168.1 gb:AF077350.1 NM_001168 baculoviral IAP repeat containing 5 BIRC5 332 NM_001012270 /// NM_001012271 /// NM_001168 /// XR_243654 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0050897 // cobalt ion binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction 202096_s_at NM_000714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000714.2 /DEF=Homo sapiens benzodiazapine receptor (peripheral) (BZRP), nuclear gene encoding mitochondrial protein, transcript variant PBR, mRNA. /FEA=mRNA /GEN=BZRP /PROD=peripheral benzodiazapine receptor /DB_XREF=gi:6382068 /UG=Hs.202 benzodiazapine receptor (peripheral) /FL=gb:BC001110.1 gb:M36035.1 gb:NM_000714.2 NM_000714 translocator protein (18kDa) TSPO 706 NM_000714 /// NM_001256530 /// NM_001256531 /// NM_007311 /// NR_046308 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008347 // glial cell migration // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010266 // response to vitamin B1 // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0032374 // regulation of cholesterol transport // traceable author statement /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060242 // contact inhibition // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071294 // cellular response to zinc ion // inferred from electronic annotation /// 0071476 // cellular hypotonic response // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005497 // androgen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // inferred from electronic annotation /// 0015485 // cholesterol binding // traceable author statement 202097_at NM_005124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005124.1 /DEF=Homo sapiens nucleoporin 153kD (NUP153), mRNA. /FEA=mRNA /GEN=NUP153 /PROD=nucleoporin 153kD /DB_XREF=gi:4826871 /UG=Hs.211608 nucleoporin 153kD /FL=gb:NM_005124.1 NM_005124 nucleoporin 153kDa NUP153 9972 NM_001278209 /// NM_001278210 /// NM_005124 /// XM_005249507 /// XM_006715290 /// XM_006715291 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0075732 // viral penetration into host nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0043495 // protein anchor // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202098_s_at NM_001535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001535.1 /DEF=Homo sapiens HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 (HRMT1L1), mRNA. /FEA=mRNA /GEN=HRMT1L1 /PROD=HMT1 (hnRNP methyltransferase, S.cerevisiae)-like 1 /DB_XREF=gi:4504494 /UG=Hs.235887 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 /FL=gb:U80213.1 gb:NM_001535.1 NM_001535 protein arginine methyltransferase 2 PRMT2 3275 NM_001242864 /// NM_001242865 /// NM_001242866 /// NM_001286676 /// NM_001286677 /// NM_001286678 /// NM_001535 /// NM_206962 /// XM_005261111 /// XM_006723998 /// XM_006723999 /// XM_006724000 0006479 // protein methylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0035246 // peptidyl-arginine N-methylation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048588 // developmental cell growth // inferred from sequence or structural similarity /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035189 // Rb-E2F complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0008469 // histone-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0033142 // progesterone receptor binding // inferred from physical interaction /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 202099_s_at H42875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H42875 /FEA=EST /DB_XREF=gi:918927 /DB_XREF=est:yo68b01.s1 /CLONE=IMAGE:183049 /UG=Hs.2491 DiGeorge syndrome critical region gene 2 /FL=gb:D79985.1 gb:NM_005137.1 H42875 DiGeorge syndrome critical region gene 2 DGCR2 9993 NM_001173533 /// NM_001173534 /// NM_001184781 /// NM_005137 /// NR_033674 0007155 // cell adhesion // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202100_at BG169673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG169673 /FEA=EST /DB_XREF=gi:12676376 /DB_XREF=est:602324650F1 /CLONE=IMAGE:4427484 /UG=Hs.250811 v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) /FL=gb:M35416.1 gb:NM_002881.1 BG169673 v-ral simian leukemia viral oncogene homolog B RALB 5899 NM_002881 /// XM_005263724 /// XM_005263727 /// XM_005263728 /// XM_005263729 0000910 // cytokinesis // inferred from direct assay /// 0001928 // regulation of exocyst assembly // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 202101_s_at NM_002881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002881.1 /DEF=Homo sapiens v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RALB), mRNA. /FEA=mRNA /GEN=RALB /PROD=v-ral simian leukemia viral oncogene homolog B /DB_XREF=gi:4506404 /UG=Hs.250811 v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) /FL=gb:M35416.1 gb:NM_002881.1 NM_002881 v-ral simian leukemia viral oncogene homolog B RALB 5899 NM_002881 /// XM_005263724 /// XM_005263727 /// XM_005263728 /// XM_005263729 0000910 // cytokinesis // inferred from direct assay /// 0001928 // regulation of exocyst assembly // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 202102_s_at BF718610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF718610 /FEA=EST /DB_XREF=gi:12019523 /DB_XREF=est:KEST81 /CLONE=S90413.NIH-116-R.ab1 /UG=Hs.278675 bromodomain-containing 4 /FL=gb:NM_014299.1 BF718610 bromodomain containing 4 BRD4 23476 NM_014299 /// NM_058243 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 1901407 // regulation of phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 202103_at AI991631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991631 /FEA=EST /DB_XREF=gi:5838623 /DB_XREF=est:wr12h09.x1 /CLONE=IMAGE:2481377 /UG=Hs.278675 bromodomain-containing 4 /FL=gb:NM_014299.1 AI991631 bromodomain containing 4 BRD4 23476 NM_014299 /// NM_058243 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 1901407 // regulation of phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 202104_s_at NM_003119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003119.1 /DEF=Homo sapiens spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) (SPG7), mRNA. /FEA=mRNA /GEN=SPG7 /PROD=paraplegin /DB_XREF=gi:4507172 /UG=Hs.296847 spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) /FL=gb:NM_003119.1 NM_003119 uncharacterized LOC101930112 /// spastic paraplegia 7 (pure and complicated autosomal recessive) LOC101930112 /// SPG7 6687 /// 101930112 NM_003119 /// NM_199367 /// XM_005256321 /// XM_006721264 /// XM_006721265 /// XM_006721266 /// XR_253599 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 202105_at NM_001551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001551.1 /DEF=Homo sapiens immunoglobulin (CD79A) binding protein 1 (IGBP1), mRNA. /FEA=mRNA /GEN=IGBP1 /PROD=immunoglobulin-binding protein 1 /DB_XREF=gi:4557662 /UG=Hs.3631 immunoglobulin (CD79A) binding protein 1 /FL=gb:BC004137.1 gb:NM_001551.1 NM_001551 immunoglobulin (CD79A) binding protein 1 IGBP1 3476 NM_001551 /// XR_430521 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035306 // positive regulation of dephosphorylation // inferred from electronic annotation /// 0035308 // negative regulation of protein dephosphorylation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060632 // regulation of microtubule-based movement // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation 202106_at NM_005895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005895.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 3 (GOLGA3), mRNA. /FEA=mRNA /GEN=GOLGA3 /PROD=golgi autoantigen, golgin subfamily a, 3 /DB_XREF=gi:5174440 /UG=Hs.4953 golgi autoantigen, golgin subfamily a, 3 /FL=gb:D63997.1 gb:NM_005895.1 NM_005895 golgin A3 GOLGA3 2802 NM_001172557 /// NM_005895 /// XM_005266162 /// XM_005266164 /// XM_005266165 /// XM_005266167 /// XM_006719736 /// XM_006719737 /// XM_006719738 /// XM_006719739 /// XM_006719740 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0090498 // extrinsic component of Golgi membrane // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202107_s_at NM_004526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004526.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin) (MCM2), mRNA. /FEA=mRNA /GEN=MCM2 /PROD=minichromosome maintenance deficient (S.cerevisiae) 2 (mitotin) /DB_XREF=gi:4758705 /UG=Hs.57101 minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin) /FL=gb:D83987.1 gb:NM_004526.1 NM_004526 minichromosome maintenance complex component 2 MCM2 4171 NM_004526 /// NR_073375 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from mutant phenotype /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202108_at NM_000285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000285.1 /DEF=Homo sapiens peptidase D (PEPD), mRNA. /FEA=mRNA /GEN=PEPD /PROD=Xaa-Pro dipeptidase /DB_XREF=gi:4557834 /UG=Hs.73947 peptidase D /FL=gb:BC004305.1 gb:J04605.1 gb:NM_000285.1 NM_000285 peptidase D PEPD 5184 NM_000285 /// NM_001166056 /// NM_001166057 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202109_at NM_012402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012402.1 /DEF=Homo sapiens partner of RAC1 (arfaptin 2) (POR1), mRNA. /FEA=mRNA /GEN=POR1 /PROD=partner of RAC1 (arfaptin 2) /DB_XREF=gi:6912601 /UG=Hs.75139 partner of RAC1 (arfaptin 2) /FL=gb:BC000392.1 gb:U52522.1 gb:NM_012402.1 NM_012402 ADP-ribosylation factor interacting protein 2 ARFIP2 23647 NM_001242854 /// NM_001242855 /// NM_001242856 /// NM_012402 /// XM_005252840 0006928 // cellular component movement // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // traceable author statement 0001726 // ruffle // inferred from mutant phenotype /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // traceable author statement /// 0048365 // Rac GTPase binding // traceable author statement 202110_at NM_001866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001866.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIb (COX7B), mRNA. /FEA=mRNA /GEN=COX7B /PROD=cytochrome c oxidase subunit VIIb /DB_XREF=gi:4502990 /UG=Hs.75752 cytochrome c oxidase subunit VIIb /FL=gb:NM_001866.1 NM_001866 cytochrome c oxidase subunit VIIb COX7B 1349 NM_001866 0007417 // central nervous system development // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 202111_at NM_003040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003040.1 /DEF=Homo sapiens solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (SLC4A2), mRNA. /FEA=mRNA /GEN=SLC4A2 /PROD=solute carrier family 4, anion exchanger, member2 (erythrocyte membrane protein band 3-like 1) /DB_XREF=gi:4507022 /UG=Hs.79410 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) /FL=gb:U62531.1 gb:NM_003040.1 NM_003040 solute carrier family 4 (anion exchanger), member 2 SLC4A2 6522 NM_001199692 /// NM_001199693 /// NM_001199694 /// NM_003040 /// XM_006716094 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // traceable author statement /// 0015108 // chloride transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 202112_at NM_000552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000552.2 /DEF=Homo sapiens von Willebrand factor (VWF), mRNA. /FEA=mRNA /GEN=VWF /PROD=von Willebrand factor precursor /DB_XREF=gi:9257255 /UG=Hs.110802 von Willebrand factor /FL=gb:NM_000552.2 NM_000552 von Willebrand factor VWF 7450 NM_000552 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007596 // blood coagulation // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from mutant phenotype /// 0009611 // response to wounding // traceable author statement /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031091 // platelet alpha granule // non-traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0002020 // protease binding // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0019865 // immunoglobulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay 202113_s_at AF043453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043453.1 /DEF=Homo sapiens sorting nexin 2 (SNX2) mRNA, complete cds. /FEA=mRNA /GEN=SNX2 /PROD=sorting nexin 2 /DB_XREF=gi:2827433 /UG=Hs.11183 sorting nexin 2 /FL=gb:BC003382.1 gb:AF043453.1 gb:AF065482.1 gb:NM_003100.1 AF043453 sorting nexin 2 SNX2 6643 NM_001278199 /// NM_003100 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded 202114_at NM_003100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003100.1 /DEF=Homo sapiens sorting nexin 2 (SNX2), mRNA. /FEA=mRNA /GEN=SNX2 /PROD=sorting nexin 2 /DB_XREF=gi:4507140 /UG=Hs.11183 sorting nexin 2 /FL=gb:BC003382.1 gb:AF043453.1 gb:AF065482.1 gb:NM_003100.1 NM_003100 sorting nexin 2 SNX2 6643 NM_001278199 /// NM_003100 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded 202115_s_at NM_015658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015658.1 /DEF=Homo sapiens DKFZP564C186 protein (DKFZP564C186), mRNA. /FEA=mRNA /GEN=DKFZP564C186 /PROD=DKFZP564C186 protein /DB_XREF=gi:7661605 /UG=Hs.134200 DKFZP564C186 protein /FL=gb:BC003555.1 gb:NM_015658.1 NM_015658 nucleolar complex associated 2 homolog (S. cerevisiae) NOC2L 26155 NM_015658 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002903 // negative regulation of B cell apoptotic process // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay /// 0032066 // nucleolus to nucleoplasm transport // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from direct assay 202116_at NM_006268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006268.2 /DEF=Homo sapiens requiem, apoptosis response zinc finger gene (REQ), mRNA. /FEA=mRNA /GEN=REQ /PROD=requiem /DB_XREF=gi:10862706 /UG=Hs.13495 requiem, apoptosis response zinc finger gene /FL=gb:NM_006268.2 gb:U94585.1 gb:AF001433.1 NM_006268 D4, zinc and double PHD fingers family 2 DPF2 5977 NM_006268 /// XM_005274149 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202117_at BG468434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG468434 /FEA=EST /DB_XREF=gi:13400704 /DB_XREF=est:602510404F1 /CLONE=IMAGE:4644528 /UG=Hs.138860 Rho GTPase activating protein 1 /FL=gb:NM_004308.1 BG468434 Rho GTPase activating protein 1 ARHGAP1 392 NM_004308 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 202118_s_at AA541758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA541758 /FEA=EST /DB_XREF=gi:2288192 /DB_XREF=est:ni87d05.s1 /CLONE=IMAGE:983817 /UG=Hs.14158 copine III /FL=gb:AB014536.1 gb:NM_003909.1 gb:AF077226.2 AA541758 copine III CPNE3 8895 NM_003909 /// XM_005251093 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202119_s_at NM_003909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003909.1 /DEF=Homo sapiens copine III (CPNE3), mRNA. /FEA=mRNA /GEN=CPNE3 /PROD=copine III /DB_XREF=gi:4503014 /UG=Hs.14158 copine III /FL=gb:AB014536.1 gb:NM_003909.1 gb:AF077226.2 NM_003909 copine III CPNE3 8895 NM_003909 /// XM_005251093 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202120_x_at NM_004069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004069.2 /DEF=Homo sapiens adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17, mRNA. /FEA=mRNA /GEN=AP2S1 /PROD=adaptor-related protein complex 2, sigma 1subunit, isoform AP17 /DB_XREF=gi:11038644 /UG=Hs.119591 adaptor-related protein complex 2, sigma 1 subunit /FL=gb:NM_004069.2 NM_004069 adaptor-related protein complex 2, sigma 1 subunit AP2S1 1175 NM_004069 /// NM_021575 /// XM_005258499 /// XM_005258500 /// XM_006723004 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030100 // regulation of endocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005215 // transporter activity // non-traceable author statement /// 0008565 // protein transporter activity // non-traceable author statement 202121_s_at NM_014453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014453.1 /DEF=Homo sapiens putative breast adenocarcinoma marker (32kD) (BC-2), mRNA. /FEA=mRNA /GEN=BC-2 /PROD=putative breast adenocarcinoma marker (32kD) /DB_XREF=gi:7656921 /UG=Hs.12107 putative breast adenocarcinoma marker (32kD) /FL=gb:AF042384.1 gb:NM_014453.1 NM_014453 charged multivesicular body protein 2A CHMP2A 27243 NM_014453 /// NM_198426 /// XM_005258746 /// XM_005258747 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0050792 // regulation of viral process // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 1902188 // positive regulation of viral release from host cell // inferred from mutant phenotype 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202122_s_at NM_005817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005817.1 /DEF=Homo sapiens cargo selection protein (mannose 6 phosphate receptor binding protein) (TIP47), mRNA. /FEA=mRNA /GEN=TIP47 /PROD=cargo selection protein (mannose 6 phosphatereceptor binding protein) /DB_XREF=gi:5032182 /UG=Hs.140452 cargo selection protein (mannose 6 phosphate receptor binding protein) /FL=gb:AF057140.1 gb:AF051314.1 gb:AF051315.1 gb:AF055574.1 gb:NM_005817.1 NM_005817 perilipin 3 PLIN3 10226 NM_001164189 /// NM_001164194 /// NM_005817 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202123_s_at NM_005157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005157.2 /DEF=Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1), transcript variant a, mRNA. /FEA=mRNA /GEN=ABL1 /PROD=v-abl Abelson murine leukemia viral oncogenehomolog 1 isoform a /DB_XREF=gi:6382056 /UG=Hs.146355 v-abl Abelson murine leukemia viral oncogene homolog 1 /FL=gb:M14752.1 gb:NM_005157.2 NM_005157 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1 25 NM_005157 /// NM_007313 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030100 // regulation of endocytosis // traceable author statement /// 0030155 // regulation of cell adhesion // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051353 // positive regulation of oxidoreductase activity // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003785 // actin monomer binding // traceable author statement /// 0004515 // nicotinate-nucleotide adenylyltransferase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 202124_s_at AV705253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705253 /FEA=EST /DB_XREF=gi:10722559 /DB_XREF=est:AV705253 /CLONE=ADBBQF03 /UG=Hs.154248 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 /FL=gb:AB038951.1 gb:NM_015049.1 AV705253 trafficking protein, kinesin binding 2 TRAK2 66008 NM_015049 /// XM_006712714 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // non-traceable author statement 202125_s_at NM_015049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015049.1 /DEF=Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 (ALS2CR3), mRNA. /FEA=mRNA /GEN=ALS2CR3 /PROD=amyotrophic lateral sclerosis 2 (juvenile)chromosome region, candidate 3 /DB_XREF=gi:13027379 /UG=Hs.154248 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 /FL=gb:AB038951.1 gb:NM_015049.1 NM_015049 trafficking protein, kinesin binding 2 TRAK2 66008 NM_015049 /// XM_006712714 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // non-traceable author statement 202126_at AA156948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156948 /FEA=EST /DB_XREF=gi:1728563 /DB_XREF=est:zl19f02.s1 /CLONE=IMAGE:502395 /UG=Hs.198891 serinethreonine-protein kinase PRP4 homolog /FL=gb:U48736.1 gb:NM_003913.1 AA156948 pre-mRNA processing factor 4B PRPF4B 8899 NM_003913 /// NM_176800 /// XM_006715238 /// XR_241936 /// XR_241940 /// XR_241944 /// XR_241945 /// XR_241947 /// XR_241948 /// XR_241949 /// XR_427838 /// XR_427839 /// XR_427840 /// XR_427841 /// XR_427842 /// XR_427843 /// XR_427844 /// XR_427845 /// XR_427846 /// XR_427847 /// XR_427848 /// XR_427849 /// XR_427850 /// XR_427851 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202127_at AB011108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011108.1 /DEF=Homo sapiens mRNA for KIAA0536 protein, partial cds. /FEA=mRNA /GEN=KIAA0536 /PROD=KIAA0536 protein /DB_XREF=gi:3043595 /UG=Hs.198891 serinethreonine-protein kinase PRP4 homolog /FL=gb:U48736.1 gb:NM_003913.1 AB011108 pre-mRNA processing factor 4B PRPF4B 8899 NM_003913 /// NM_176800 /// XM_006715238 /// XR_241936 /// XR_241940 /// XR_241944 /// XR_241945 /// XR_241947 /// XR_241948 /// XR_241949 /// XR_427838 /// XR_427839 /// XR_427840 /// XR_427841 /// XR_427842 /// XR_427843 /// XR_427844 /// XR_427845 /// XR_427846 /// XR_427847 /// XR_427848 /// XR_427849 /// XR_427850 /// XR_427851 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202128_at NM_014821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014821.1 /DEF=Homo sapiens KIAA0317 gene product (KIAA0317), mRNA. /FEA=mRNA /GEN=KIAA0317 /PROD=KIAA0317 gene product /DB_XREF=gi:7662051 /UG=Hs.20126 KIAA0317 gene product /FL=gb:AB002315.1 gb:NM_014821.1 NM_014821 apoptosis resistant E3 ubiquitin protein ligase 1 AREL1 9870 NM_001039479 /// NM_014821 /// XM_005268244 /// XM_006720344 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation 202129_s_at AW006290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006290 /FEA=EST /DB_XREF=gi:5855068 /DB_XREF=est:wq69f11.x1 /CLONE=IMAGE:2476557 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1 AW006290 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202130_at AA725102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA725102 /FEA=EST /DB_XREF=gi:2742809 /DB_XREF=est:ai08h05.s1 /CLONE=1342233 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1 AA725102 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202131_s_at NM_003831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003831.1 /DEF=Homo sapiens sudD (suppressor of bimD6, Aspergillus nidulans) homolog (SUDD), mRNA. /FEA=mRNA /GEN=SUDD /PROD=sudD (suppressor of bimD6, Aspergillus nidulans)homolog /DB_XREF=gi:4507298 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1 NM_003831 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202132_at AA081084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA081084 /FEA=EST /DB_XREF=gi:1623002 /DB_XREF=est:zn32h12.s1 /CLONE=IMAGE:549191 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1 AA081084 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202133_at BF674349 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF674349 /FEA=EST /DB_XREF=gi:11948244 /DB_XREF=est:602137094F1 /CLONE=IMAGE:4273679 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1 BF674349 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202134_s_at NM_015472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015472.1 /DEF=Homo sapiens transcriptional co-activator with PDZ-binding motif (TAZ) (TAZ), mRNA. /FEA=mRNA /GEN=TAZ /PROD=transcriptional co-activator with PDZ-bindingmotif (TAZ) /DB_XREF=gi:13346497 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1 NM_015472 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202135_s_at NM_005735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005735.2 /DEF=Homo sapiens ARP1 (actin-related protein 1, yeast) homolog B (centractin beta) (ACTR1B), mRNA. /FEA=mRNA /GEN=ACTR1B /PROD=actin-related protein 1B /DB_XREF=gi:13325060 /UG=Hs.2477 ARP1 (actin-related protein 1, yeast) homolog B (centractin beta) /FL=gb:NM_005735.2 gb:BC004374.1 NM_005735 ARP1 actin-related protein 1 homolog B, centractin beta (yeast) ACTR1B 10120 NM_005735 /// XM_005263854 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 202136_at BE250417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE250417 /FEA=EST /DB_XREF=gi:9120528 /DB_XREF=est:600943460T1 /CLONE=IMAGE:2959935 /UG=Hs.301449 adenovirus 5 E1A binding protein /FL=gb:NM_006624.1 BE250417 zinc finger, MYND-type containing 11 ZMYND11 10771 NM_001202464 /// NM_001202465 /// NM_001202466 /// NM_001202467 /// NM_001202468 /// NM_006624 /// NM_212479 /// XM_005252359 /// XM_005252360 /// XM_005252361 /// XM_005252362 /// XM_005252363 /// XM_006717376 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034243 // regulation of transcription elongation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202137_s_at NM_006624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006624.1 /DEF=Homo sapiens adenovirus 5 E1A binding protein (BS69), mRNA. /FEA=mRNA /GEN=BS69 /PROD=adenovirus 5 E1A binding protein /DB_XREF=gi:5729745 /UG=Hs.301449 adenovirus 5 E1A binding protein /FL=gb:NM_006624.1 NM_006624 zinc finger, MYND-type containing 11 ZMYND11 10771 NM_001202464 /// NM_001202465 /// NM_001202466 /// NM_001202467 /// NM_001202468 /// NM_006624 /// NM_212479 /// XM_005252359 /// XM_005252360 /// XM_005252361 /// XM_005252362 /// XM_005252363 /// XM_006717376 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034243 // regulation of transcription elongation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202138_x_at NM_006303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006303.2 /DEF=Homo sapiens JTV1 gene (JTV1), mRNA. /FEA=mRNA /GEN=JTV1 /PROD=JTV1 /DB_XREF=gi:11125769 /UG=Hs.301613 JTV1 gene /FL=gb:NM_006303.2 gb:U24169.1 gb:BC002853.1 NM_006303 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 AIMP2 7965 NM_006303 /// XM_005249847 /// XM_005249848 /// XM_005249850 /// XM_006715772 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 202139_at NM_003689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003689.1 /DEF=Homo sapiens aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2), mRNA. /FEA=mRNA /GEN=AKR7A2 /PROD=aldo-keto reductase family 7, member A2(aflatoxin aldehyde reductase) /DB_XREF=gi:4502020 /UG=Hs.6980 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) /FL=gb:BC004111.1 gb:AF026947.1 gb:NM_003689.1 NM_003689 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) AKR7A2 8574 NM_003689 0005975 // carbohydrate metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019119 // phenanthrene-9,10-epoxide hydrolase activity // inferred from direct assay 202140_s_at NM_003992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003992.1 /DEF=Homo sapiens CDC-like kinase 3 (CLK3), transcript variant phclk3, mRNA. /FEA=mRNA /GEN=CLK3 /PROD=CDC-like kinase 3 isoform hclk3 /DB_XREF=gi:4502884 /UG=Hs.73987 CDC-like kinase 3 /FL=gb:BC002555.1 gb:NM_003992.1 gb:L29217.1 NM_003992 CDC-like kinase 3 CLK3 1198 NM_001130028 /// NM_001292 /// NM_003992 /// XM_005254151 /// XM_005254152 /// XM_005254153 /// XM_005254154 /// XM_006720383 /// XM_006720384 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202141_s_at BC003090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003090.1 /DEF=Homo sapiens, COP9 homolog, clone MGC:1297, mRNA, complete cds. /FEA=mRNA /PROD=COP9 homolog /DB_XREF=gi:13111846 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1 BC003090 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202142_at BC003090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003090.1 /DEF=Homo sapiens, COP9 homolog, clone MGC:1297, mRNA, complete cds. /FEA=mRNA /PROD=COP9 homolog /DB_XREF=gi:13111846 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1 BC003090 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202143_s_at NM_006710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006710.1 /DEF=Homo sapiens COP9 homolog (COP9), mRNA. /FEA=mRNA /GEN=COP9 /PROD=COP9 homolog /DB_XREF=gi:5729778 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1 NM_006710 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202144_s_at NM_000026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000026.1 /DEF=Homo sapiens adenylosuccinate lyase (ADSL), mRNA. /FEA=mRNA /GEN=ADSL /PROD=adenylosuccinate lyase /DB_XREF=gi:4557268 /UG=Hs.75527 adenylosuccinate lyase /FL=gb:AF067853.1 gb:NM_000026.1 NM_000026 adenylosuccinate lyase ADSL 158 NM_000026 /// NM_001123378 0001666 // response to hypoxia // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006163 // purine nucleotide metabolic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred by curator /// 0006167 // AMP biosynthetic process // inferred from direct assay /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009152 // purine ribonucleotide biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044208 // 'de novo' AMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // inferred from direct assay /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0070626 // (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity // inferred from electronic annotation 202145_at NM_002346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002346.1 /DEF=Homo sapiens lymphocyte antigen 6 complex, locus E (LY6E), mRNA. /FEA=mRNA /GEN=LY6E /PROD=lymphocyte antigen 6 complex, locus E /DB_XREF=gi:4505048 /UG=Hs.77667 lymphocyte antigen 6 complex, locus E /FL=gb:U42376.1 gb:U56145.1 gb:NM_002346.1 NM_002346 lymphocyte antigen 6 complex, locus E LY6E 4061 NM_001127213 /// NM_002346 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0048242 // epinephrine secretion // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 202146_at AA747426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA747426 /FEA=EST /DB_XREF=gi:2787384 /DB_XREF=est:nx88e08.s1 /CLONE=IMAGE:1269350 /UG=Hs.7879 interferon-related developmental regulator 1 /FL=gb:BC001272.1 gb:NM_001550.1 AA747426 interferon-related developmental regulator 1 IFRD1 3475 NM_001007245 /// NM_001197079 /// NM_001197080 /// NM_001550 /// NR_120333 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007518 // myoblast fate determination // traceable author statement /// 0007527 // adult somatic muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 202147_s_at NM_001550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001550.1 /DEF=Homo sapiens interferon-related developmental regulator 1 (IFRD1), mRNA. /FEA=mRNA /GEN=IFRD1 /PROD=interferon-related developmental regulator 1 /DB_XREF=gi:4504606 /UG=Hs.7879 interferon-related developmental regulator 1 /FL=gb:BC001272.1 gb:NM_001550.1 NM_001550 interferon-related developmental regulator 1 IFRD1 3475 NM_001007245 /// NM_001197079 /// NM_001197080 /// NM_001550 /// NR_120333 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007518 // myoblast fate determination // traceable author statement /// 0007527 // adult somatic muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 202148_s_at NM_006907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006907.1 /DEF=Homo sapiens pyrroline-5-carboxylate reductase 1 (PYCR1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PYCR1 /PROD=pyrroline-5-carboxylate reductase 1 /DB_XREF=gi:5902035 /UG=Hs.79217 pyrroline-5-carboxylate reductase 1 /FL=gb:M77836.1 gb:NM_006907.1 NM_006907 pyrroline-5-carboxylate reductase 1 PYCR1 5831 NM_001282279 /// NM_001282280 /// NM_001282281 /// NM_006907 /// NM_153824 /// XM_005256381 /// XM_006722286 0006561 // proline biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046168 // glycerol-3-phosphate catabolic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0004735 // pyrroline-5-carboxylate reductase activity // inferred from direct assay /// 0004735 // pyrroline-5-carboxylate reductase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051287 // NAD binding // inferred from electronic annotation 202149_at AL136139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136139 /DEF=Human DNA sequence from clone RP4-761I2 on chromosome 6 Contains 3 part of the gene for enhancer of filamentation (HEF1), ESTs, STSs and CpG islands /FEA=mRNA /DB_XREF=gi:8217463 /UG=Hs.80261 enhancer of filamentation 1 (cas-like docking; Crk-associated substrate related) /FL=gb:L43821.1 gb:U64317.1 gb:NM_006403.1 AL136139 neural precursor cell expressed, developmentally down-regulated 9 NEDD9 4739 NM_001142393 /// NM_001271033 /// NM_006403 /// NM_182966 /// NR_073131 0007010 // cytoskeleton organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202150_s_at U64317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U64317.1 /DEF=Human Crk-associated substrate related protein Cas-L mRNA, complete cds. /FEA=mRNA /PROD=Crk-associated substrate related protein Cas-L /DB_XREF=gi:1490786 /UG=Hs.80261 enhancer of filamentation 1 (cas-like docking; Crk-associated substrate related) /FL=gb:L43821.1 gb:U64317.1 gb:NM_006403.1 U64317 neural precursor cell expressed, developmentally down-regulated 9 NEDD9 4739 NM_001142393 /// NM_001271033 /// NM_006403 /// NM_182966 /// NR_073131 0007010 // cytoskeleton organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202151_s_at NM_016172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016172.1 /DEF=Homo sapiens putative glialblastoma cell differentiation-related (GDBR1), mRNA. /FEA=mRNA /GEN=GDBR1 /PROD=putative glialblastoma celldifferentiation-related protein /DB_XREF=gi:7705380 /UG=Hs.9194 putative glialblastoma cell differentiation-related /FL=gb:BC004967.1 gb:AF176796.1 gb:NM_016172.1 NM_016172 UBA domain containing 1 UBAC1 10422 NM_016172 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202152_x_at NM_003367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003367.1 /DEF=Homo sapiens upstream transcription factor 2, c-fos interacting (USF2), mRNA. /FEA=mRNA /GEN=USF2 /PROD=upstream transcription factor 2, c-fosinteracting /DB_XREF=gi:4507846 /UG=Hs.93649 upstream transcription factor 2, c-fos interacting /FL=gb:NM_003367.1 NM_003367 upstream transcription factor 2, c-fos interacting USF2 7392 NM_003367 /// NM_207291 /// XM_005259197 0000430 // regulation of transcription from RNA polymerase II promoter by glucose // inferred by curator /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from mutant phenotype /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007595 // lactation // inferred from electronic annotation /// 0019086 // late viral transcription // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 202153_s_at NM_016553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016553.1 /DEF=Homo sapiens hypothetical protein (DKFZp547L134), mRNA. /FEA=mRNA /GEN=DKFZp547L134 /PROD=hypothetical protein /DB_XREF=gi:7705354 /UG=Hs.9877 hypothetical protein /FL=gb:AL162061.1 gb:NM_016553.1 NM_016553 nucleoporin 62kDa NUP62 23636 NM_001193357 /// NM_012346 /// NM_016553 /// NM_153718 /// NM_153719 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008645 // hexose transport // traceable author statement /// 0009755 // hormone-mediated signaling pathway // non-traceable author statement /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031074 // nucleocytoplasmic shuttling complex // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0046930 // pore complex // non-traceable author statement 0003682 // chromatin binding // non-traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from sequence or structural similarity /// 0051425 // PTB domain binding // inferred from electronic annotation 202154_x_at NM_006086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006086.1 /DEF=Homo sapiens tubulin, beta, 4 (TUBB4), mRNA. /FEA=mRNA /GEN=TUBB4 /PROD=tubulin, beta, 4 /DB_XREF=gi:5174736 /UG=Hs.159154 tubulin, beta, 4 /FL=gb:BC000748.1 gb:U47634.1 gb:NM_006086.1 NM_006086 tubulin, beta 3 class III TUBB3 10381 NM_001197181 /// NM_006086 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202155_s_at NM_005085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005085.1 /DEF=Homo sapiens nucleoporin 214kD (CAIN) (NUP214), mRNA. /FEA=mRNA /GEN=NUP214 /PROD=nucleoporin 214kD (CAIN) /DB_XREF=gi:4826873 /UG=Hs.170285 nucleoporin 214kD (CAIN) /FL=gb:NM_005085.1 NM_005085 nucleoporin 214kDa NUP214 8021 NM_005085 /// XM_005272216 /// XM_005272217 /// XM_005272218 /// XM_005272219 /// XM_006717292 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202156_s_at N36839 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36839 /FEA=EST /DB_XREF=gi:1157981 /DB_XREF=est:yy35f07.s1 /CLONE=IMAGE:273253 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1 N36839 CUGBP, Elav-like family member 2 CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202157_s_at U69546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U69546.1 /DEF=Homo sapiens RNA-binding protein BRUNOL3 (BRUNOL3) mRNA, complete cds. /FEA=mRNA /GEN=BRUNOL3 /PROD=RNA-binding protein BRUNOL3 /DB_XREF=gi:1568642 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1 U69546 CUGBP, Elav-like family member 2 CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202158_s_at NM_006561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006561.1 /DEF=Homo sapiens CUG triplet repeat, RNA-binding protein 2 (CUGBP2), mRNA. /FEA=mRNA /GEN=CUGBP2 /PROD=CUG triplet repeat, RNA-binding protein 2 /DB_XREF=gi:5729815 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1 NM_006561 CUGBP, Elav-like family member 2 CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202159_at NM_004461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004461.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase-like (FARSL), mRNA. /FEA=mRNA /GEN=FARSL /PROD=phenylalanine-tRNA synthetase-like protein /DB_XREF=gi:4758339 /UG=Hs.23111 phenylalanine-tRNA synthetase-like /FL=gb:U07424.1 gb:AF042347.1 gb:NM_004461.1 gb:D84471.1 NM_004461 phenylalanyl-tRNA synthetase, alpha subunit FARSA 2193 NM_004461 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202160_at NM_004380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004380.1 /DEF=Homo sapiens CREB binding protein (Rubinstein-Taybi syndrome) (CREBBP), mRNA. /FEA=mRNA /GEN=CREBBP /PROD=CREB binding protein /DB_XREF=gi:4758055 /UG=Hs.23598 CREB binding protein (Rubinstein-Taybi syndrome) /FL=gb:U47741.1 gb:NM_004380.1 NM_004380 CREB binding protein CREBBP 1387 NM_001079846 /// NM_004380 /// XM_005255124 /// XM_005255125 /// XM_006720848 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // traceable author statement /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042733 // embryonic digit morphogenesis // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001102 // RNA polymerase II activating transcription factor binding // traceable author statement /// 0001105 // RNA polymerase II transcription coactivator activity // traceable author statement /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from physical interaction /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043426 // MRF binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 202161_at NM_002741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002741.1 /DEF=Homo sapiens protein kinase C-like 1 (PRKCL1), mRNA. /FEA=mRNA /GEN=PRKCL1 /PROD=protein kinase C-like 1 /DB_XREF=gi:4506072 /UG=Hs.2499 protein kinase C-like 1 /FL=gb:U33053.1 gb:NM_002741.1 gb:D26181.1 NM_002741 protein kinase N1 PKN1 5585 NM_002741 /// NM_213560 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0010631 // epithelial cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035407 // histone H3-T11 phosphorylation // inferred from direct assay /// 2000145 // regulation of cell motility // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035402 // histone kinase activity (H3-T11 specific) // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay 202162_s_at AI769416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769416 /FEA=EST /DB_XREF=gi:5235925 /DB_XREF=est:wj13f08.x1 /CLONE=IMAGE:2402727 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1 AI769416 CCR4-NOT transcription complex, subunit 8 CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202163_s_at NM_004779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004779.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 8 (CNOT8), mRNA. /FEA=mRNA /GEN=CNOT8 /PROD=CCR4-NOT transcription complex, subunit 8 /DB_XREF=gi:4758945 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1 NM_004779 CCR4-NOT transcription complex, subunit 8 CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202164_s_at AF180476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180476.1 /DEF=Homo sapiens CALIFp (CALIF) mRNA, complete cds. /FEA=mRNA /GEN=CALIF /PROD=CALIFp /DB_XREF=gi:6856208 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1 AF180476 CCR4-NOT transcription complex, subunit 8 CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202165_at BF966540 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF966540 /FEA=EST /DB_XREF=gi:12333755 /DB_XREF=est:602287009T1 /CLONE=IMAGE:4375586 /UG=Hs.267819 protein phosphatase 1, regulatory (inhibitor) subunit 2 /FL=gb:NM_006241.1 BF966540 protein phosphatase 1, regulatory (inhibitor) subunit 2 PPP1R2 5504 NM_001291504 /// NM_001291505 /// NM_006241 /// XM_006713682 /// XM_006713683 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202166_s_at NM_006241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006241.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 2 (PPP1R2), mRNA. /FEA=mRNA /GEN=PPP1R2 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 2 /DB_XREF=gi:5453945 /UG=Hs.267819 protein phosphatase 1, regulatory (inhibitor) subunit 2 /FL=gb:NM_006241.1 NM_006241 protein phosphatase 1, regulatory (inhibitor) subunit 2 PPP1R2 5504 NM_001291504 /// NM_001291505 /// NM_006241 /// XM_006713682 /// XM_006713683 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202167_s_at NM_022362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022362.1 /DEF=Homo sapiens MMS19 (MET18 S. cerevisiae)-like (MMS19L), mRNA. /FEA=mRNA /GEN=MMS19L /PROD=MMS19 (MET18 S. cerevisiae)-like /DB_XREF=gi:13375625 /UG=Hs.288891 MMS19 (MET18 S. cerevisiae)-like /FL=gb:NM_022362.1 NM_022362 MMS19 nucleotide excision repair homolog (S. cerevisiae) MMS19 64210 NM_001289403 /// NM_001289404 /// NM_001289405 /// NM_022362 /// XM_005270035 /// XM_005270041 /// XM_006717944 /// XM_006717945 /// XR_428713 0000160 // phosphorelay signal transduction system // non-traceable author statement /// 0006259 // DNA metabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // non-traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0009725 // response to hormone // non-traceable author statement /// 0016226 // iron-sulfur cluster assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005675 // holo TFIIH complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement 202168_at NM_003187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003187.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD (TAF2G), mRNA. /FEA=mRNA /GEN=TAF2G /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, G, 32kD /DB_XREF=gi:4507350 /UG=Hs.60679 TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD /FL=gb:BC003400.1 gb:NM_003187.1 gb:U21858.1 gb:U25112.1 gb:U30504.1 NM_003187 adenylate kinase 6 /// TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa AK6 /// TAF9 6880 /// 102157402 NM_001015891 /// NM_001015892 /// NM_003187 /// NM_016283 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060760 // positive regulation of response to cytokine stimulus // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202169_s_at AF302110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF302110.1 /DEF=Homo sapiens alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase mRNA, complete cds. /FEA=mRNA /PROD=alpha-aminoadipic semialdehydedehydrogenase-phosphopantetheinyl transferase /DB_XREF=gi:11120434 /UG=Hs.64595 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase /FL=gb:AF302110.1 gb:AF136978.1 gb:AF151838.1 gb:AF151057.1 gb:NM_015423.1 gb:AF201943.1 AF302110 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase AASDHPPT 60496 NM_015423 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008897 // holo-[acyl-carrier-protein] synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202170_s_at AF151057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151057.1 /DEF=Homo sapiens HSPC223 mRNA, complete cds. /FEA=mRNA /PROD=HSPC223 /DB_XREF=gi:7106835 /UG=Hs.64595 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase /FL=gb:AF302110.1 gb:AF136978.1 gb:AF151838.1 gb:AF151057.1 gb:NM_015423.1 gb:AF201943.1 AF151057 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase AASDHPPT 60496 NM_015423 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008897 // holo-[acyl-carrier-protein] synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202171_at AU146275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146275 /FEA=EST /DB_XREF=gi:11007796 /DB_XREF=est:AU146275 /CLONE=HEMBB1000004 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1 AU146275 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202172_at BG035116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG035116 /FEA=EST /DB_XREF=gi:12428927 /DB_XREF=est:602324811F1 /CLONE=IMAGE:4412907 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1 BG035116 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202173_s_at NM_007146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007146.1 /DEF=Homo sapiens zinc finger protein 161 (ZNF161), mRNA. /FEA=mRNA /GEN=ZNF161 /PROD=zinc finger protein 161 /DB_XREF=gi:6005967 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1 NM_007146 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202174_s_at NM_006197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006197.1 /DEF=Homo sapiens pericentriolar material 1 (PCM1), mRNA. /FEA=mRNA /GEN=PCM1 /PROD=pericentriolar material 1 /DB_XREF=gi:5453855 /UG=Hs.75737 pericentriolar material 1 /FL=gb:L27841.1 gb:NM_006197.1 NM_006197 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 202175_at NM_024536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024536.1 /DEF=Homo sapiens hypothetical protein FLJ22678 (FLJ22678), mRNA. /FEA=mRNA /GEN=FLJ22678 /PROD=hypothetical protein FLJ22678 /DB_XREF=gi:13375692 /UG=Hs.7718 hypothetical protein FLJ22678 /FL=gb:NM_024536.1 NM_024536 chondroitin polymerizing factor CHPF 79586 NM_001195731 /// NM_024536 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation 202176_at NM_000122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000122.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), mRNA. /FEA=mRNA /GEN=ERCC3 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 3 (xerodermapigmentosum group B complementing) /DB_XREF=gi:4557562 /UG=Hs.77929 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) /FL=gb:M31899.1 gb:NM_000122.1 NM_000122 excision repair cross-complementation group 3 ERCC3 2071 NM_000122 /// XM_005263618 0000717 // nucleotide-excision repair, DNA duplex unwinding // inferred from mutant phenotype /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006265 // DNA topological change // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0008104 // protein localization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from mutant phenotype /// 0009650 // UV protection // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0033683 // nucleotide-excision repair, DNA incision // inferred from mutant phenotype /// 0035315 // hair cell differentiation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement /// 1901990 // regulation of mitotic cell cycle phase transition // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005675 // holo TFIIH complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // non-traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from mutant phenotype /// 0008134 // transcription factor binding // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0032564 // dATP binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043138 // 3'-5' DNA helicase activity // inferred from direct assay /// 0043138 // 3'-5' DNA helicase activity // inferred from mutant phenotype /// 0047485 // protein N-terminus binding // inferred from physical interaction 202177_at NM_000820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000820.1 /DEF=Homo sapiens growth arrest-specific 6 (GAS6), mRNA. /FEA=mRNA /GEN=GAS6 /PROD=growth arrest-specific 6 /DB_XREF=gi:4557616 /UG=Hs.78501 growth arrest-specific 6 /FL=gb:L13720.1 gb:NM_000820.1 NM_000820 growth arrest-specific 6 GAS6 2621 NM_000820 /// NM_001143945 /// NM_001143946 0001764 // neuron migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010934 // macrophage cytokine production // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0019079 // viral genome replication // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035754 // B cell chemotaxis // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046718 // viral entry into host cell // inferred from direct assay /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050711 // negative regulation of interleukin-1 secretion // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070168 // negative regulation of biomineral tissue development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071307 // cellular response to vitamin K // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 0097241 // hematopoietic stem cell migration to bone marrow // inferred from direct assay /// 1900142 // negative regulation of oligodendrocyte apoptotic process // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from direct assay /// 2000533 // negative regulation of renal albumin absorption // inferred from sequence or structural similarity /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred from direct assay /// 0060090 // binding, bridging // inferred from direct assay 202178_at NM_002744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002744.2 /DEF=Homo sapiens protein kinase C, zeta (PRKCZ), mRNA. /FEA=mRNA /GEN=PRKCZ /PROD=protein kinase C, zeta /DB_XREF=gi:10864649 /UG=Hs.78793 protein kinase C, zeta /FL=gb:NM_002744.2 gb:L14283.1 NM_002744 protein kinase C, zeta PRKCZ 5590 NM_001033581 /// NM_001033582 /// NM_001242874 /// NM_002744 /// XM_006710764 /// XM_006710765 /// XM_006710766 /// XM_006710767 /// XM_006710768 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from electronic annotation /// 0032148 // activation of protein kinase B activity // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070528 // protein kinase C signaling // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity /// 2000664 // positive regulation of interleukin-5 secretion // inferred from sequence or structural similarity /// 2000667 // positive regulation of interleukin-13 secretion // inferred from sequence or structural similarity /// 2001181 // positive regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045179 // apical cortex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred by curator /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 202179_at NM_000386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000386.1 /DEF=Homo sapiens bleomycin hydrolase (BLMH), mRNA. /FEA=mRNA /GEN=BLMH /PROD=bleomycin hydrolase /DB_XREF=gi:4557366 /UG=Hs.78943 bleomycin hydrolase /FL=gb:BC003616.1 gb:NM_000386.1 NM_000386 bleomycin hydrolase BLMH 642 NM_000386 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // traceable author statement /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 202180_s_at NM_017458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017458.1 /DEF=Homo sapiens major vault protein (MVP), transcript variant 1, mRNA. /FEA=mRNA /GEN=MVP /PROD=major vault protein /DB_XREF=gi:9665254 /UG=Hs.80680 major vault protein /FL=gb:NM_017458.1 NM_017458 major vault protein MVP 9961 NM_001293204 /// NM_001293205 /// NM_005115 /// NM_017458 0006810 // transport // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0023057 // negative regulation of signaling // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072376 // protein activation cascade // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from direct assay 202181_at NM_014734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014734.1 /DEF=Homo sapiens KIAA0247 gene product (KIAA0247), mRNA. /FEA=mRNA /GEN=KIAA0247 /PROD=KIAA0247 gene product /DB_XREF=gi:7662019 /UG=Hs.82426 KIAA0247 gene product /FL=gb:D87434.1 gb:NM_014734.1 NM_014734 KIAA0247 KIAA0247 9766 NM_014734 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202182_at NM_021078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021078.1 /DEF=Homo sapiens GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 (GCN5L2), mRNA. /FEA=mRNA /GEN=GCN5L2 /PROD=GCN5 (general control of amino-acid synthesis,yeast, homolog)-like 2 /DB_XREF=gi:10835100 /UG=Hs.101067 GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 /FL=gb:NM_021078.1 NM_021078 K(lysine) acetyltransferase 2A KAT2A 2648 NM_021078 /// XM_006721817 /// XM_006721818 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0022037 // metencephalon development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0010484 // H3 histone acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043997 // histone acetyltransferase activity (H4-K12 specific) // inferred from electronic annotation 202183_s_at NM_007317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007317.1 /DEF=Homo sapiens kinesin-like 4 (KNSL4), mRNA. /FEA=mRNA /GEN=KNSL4 /PROD=kinesin-like 4 /DB_XREF=gi:6453817 /UG=Hs.119324 kinesin-like 4 /FL=gb:BC004352.1 gb:AB017430.2 gb:L29096.1 gb:NM_007317.1 NM_007317 kinesin family member 22 KIF22 3835 NM_001256269 /// NM_001256270 /// NM_007317 /// XR_243280 0006281 // DNA repair // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // traceable author statement /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 202184_s_at NM_018230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018230.1 /DEF=Homo sapiens hypothetical protein FLJ10814 (FLJ10814), mRNA. /FEA=mRNA /GEN=FLJ10814 /PROD=hypothetical protein FLJ10814 /DB_XREF=gi:8922689 /UG=Hs.12457 hypothetical protein FLJ10814 /FL=gb:NM_018230.1 NM_018230 nucleoporin 133kDa NUP133 55746 NM_018230 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202185_at NM_001084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001084.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), mRNA. /FEA=mRNA /GEN=PLOD3 /PROD=procollagen-lysine, 2-oxoglutarate 5-dioxygenase3v /DB_XREF=gi:4505890 /UG=Hs.153357 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 /FL=gb:AF046889.1 gb:AF068229.1 gb:NM_001084.1 NM_001084 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 PLOD3 8985 NM_001084 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0070831 // basement membrane assembly // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0033823 // procollagen glucosyltransferase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050211 // procollagen galactosyltransferase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 202186_x_at AI803525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803525 /FEA=EST /DB_XREF=gi:5368985 /DB_XREF=est:tc42h07.x1 /CLONE=IMAGE:2067325 /UG=Hs.155079 protein phosphatase 2, regulatory subunit B (B56), alpha isoform /FL=gb:L42373.1 gb:NM_006243.1 AI803525 protein phosphatase 2, regulatory subunit B', alpha PPP2R5A 5525 NM_001199756 /// NM_006243 0007165 // signal transduction // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090219 // negative regulation of lipid kinase activity // inferred from mutant phenotype 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 202187_s_at NM_006243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006243.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A), mRNA. /FEA=mRNA /GEN=PPP2R5A /PROD=protein phosphatase 2, regulatory subunit B(B56), alpha isoform /DB_XREF=gi:5453949 /UG=Hs.155079 protein phosphatase 2, regulatory subunit B (B56), alpha isoform /FL=gb:L42373.1 gb:NM_006243.1 NM_006243 protein phosphatase 2, regulatory subunit B', alpha PPP2R5A 5525 NM_001199756 /// NM_006243 0007165 // signal transduction // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090219 // negative regulation of lipid kinase activity // inferred from mutant phenotype 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 202188_at NM_014669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014669.1 /DEF=Homo sapiens KIAA0095 gene product (KIAA0095), mRNA. /FEA=mRNA /GEN=KIAA0095 /PROD=KIAA0095 gene product /DB_XREF=gi:7661901 /UG=Hs.155314 KIAA0095 gene product /FL=gb:D42085.1 gb:NM_014669.1 NM_014669 nucleoporin 93kDa NUP93 9688 NM_001242795 /// NM_001242796 /// NM_014669 /// XM_005256263 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 202189_x_at NM_002819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002819.1 /DEF=Homo sapiens polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) (PTB), mRNA. /FEA=mRNA /GEN=PTB /PROD=polypyrimidine tract binding protein(heterogeneous nuclear ribonucleoprotein I) /DB_XREF=gi:4506242 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) /FL=gb:NM_002819.1 NM_002819 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202190_at NM_001324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001324.1 /DEF=Homo sapiens cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kD (CSTF1), mRNA. /FEA=mRNA /GEN=CSTF1 /PROD=cleavage stimulation factor subunit 1 /DB_XREF=gi:4557490 /UG=Hs.172865 cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kD /FL=gb:BC001011.1 gb:L02547.1 gb:NM_001324.1 NM_001324 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa CSTF1 1477 NM_001033521 /// NM_001033522 /// NM_001324 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202191_s_at BE439987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE439987 /FEA=EST /DB_XREF=gi:9439470 /DB_XREF=est:HTM1-745F /UG=Hs.226133 growth arrest-specific 7 /FL=gb:AB007854.1 gb:NM_005890.1 BE439987 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 202192_s_at NM_005890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005890.1 /DEF=Homo sapiens growth arrest-specific 7 (GAS7), transcript variant b, mRNA. /FEA=mRNA /GEN=GAS7 /PROD=growth arrest-specific 7 isoform b /DB_XREF=gi:5360211 /UG=Hs.226133 growth arrest-specific 7 /FL=gb:AB007854.1 gb:NM_005890.1 NM_005890 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 202193_at NM_005569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005569.2 /DEF=Homo sapiens LIM domain kinase 2 (LIMK2), transcript variant 2a, mRNA. /FEA=mRNA /GEN=LIMK2 /PROD=LIM domain kinase 2 isoform 2a /DB_XREF=gi:8051619 /UG=Hs.278027 LIM domain kinase 2 /FL=gb:D45906.1 gb:NM_005569.2 NM_005569 LIM domain kinase 2 LIMK2 3985 NM_001031801 /// NM_005569 /// NM_016733 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0042325 // regulation of phosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202194_at AL117354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117354 /DEF=Human DNA sequence from clone RP5-976O13 on chromosome 1p21.2-22.2 Contains part of the gene for CGI-100 protein, 3 isoforms of the gene for M96 protein, ESTs, STSs, GSSs and a CpG Island /FEA=mRNA_1 /DB_XREF=gi:6822199 /UG=Hs.296155 CGI-100 protein /FL=gb:AF151858.1 gb:NM_016040.1 AL117354 transmembrane emp24 protein transport domain containing 5 TMED5 50999 NM_001167830 /// NM_016040 /// NR_030761 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202195_s_at NM_016040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016040.1 /DEF=Homo sapiens CGI-100 protein (LOC50999), mRNA. /FEA=mRNA /GEN=LOC50999 /PROD=CGI-100 protein /DB_XREF=gi:7705583 /UG=Hs.296155 CGI-100 protein /FL=gb:AF151858.1 gb:NM_016040.1 NM_016040 transmembrane emp24 protein transport domain containing 5 TMED5 50999 NM_001167830 /// NM_016040 /// NR_030761 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202196_s_at NM_013253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013253.1 /DEF=Homo sapiens dickkopf (Xenopus laevis) homolog 3 (DKK3), mRNA. /FEA=mRNA /GEN=DKK3 /PROD=Dickkopf gene 3 /DB_XREF=gi:7019362 /UG=Hs.4909 dickkopf (Xenopus laevis) homolog 3 /FL=gb:AF177396.1 gb:AB033421.1 gb:AB034203.1 gb:NM_013253.1 NM_013253 dickkopf WNT signaling pathway inhibitor 3 DKK3 27122 NM_001018057 /// NM_013253 /// NM_015881 /// XM_006718177 /// XM_006718178 /// XM_006718179 /// XM_006718180 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from expression pattern /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202197_at NM_021090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021090.1 /DEF=Homo sapiens myotubularin related protein 3 (MTMR3), mRNA. /FEA=mRNA /GEN=MTMR3 /PROD=myotubularin related protein 3 /DB_XREF=gi:10835108 /UG=Hs.63302 myotubularin related protein 3 /FL=gb:NM_021090.1 gb:AB002369.1 gb:AF233438.1 NM_021090 myotubularin related protein 3 MTMR3 8897 NM_001013676 /// NM_021090 /// NM_153050 /// NM_153051 /// XM_005261803 /// XM_005261804 /// XM_005261805 /// XM_005261806 /// XM_005261807 /// XM_005261808 /// XM_005261809 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202198_s_at AF233438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF233438.1 /DEF=Homo sapiens FYVE domain-containing dual specificity protein phosphatase FYVE-DSP1c mRNA, complete cds. /FEA=mRNA /PROD=FYVE domain-containing dual specificity proteinphosphatase FYVE-DSP1c /DB_XREF=gi:7208447 /UG=Hs.63302 myotubularin related protein 3 /FL=gb:NM_021090.1 gb:AB002369.1 gb:AF233438.1 AF233438 myotubularin related protein 3 MTMR3 8897 NM_001013676 /// NM_021090 /// NM_153050 /// NM_153051 /// XM_005261803 /// XM_005261804 /// XM_005261805 /// XM_005261806 /// XM_005261807 /// XM_005261808 /// XM_005261809 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202199_s_at AW082913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW082913 /FEA=EST /DB_XREF=gi:6038065 /DB_XREF=est:xc04c12.x1 /CLONE=IMAGE:2583286 /UG=Hs.75761 SFRS protein kinase 1 /FL=gb:NM_003137.1 gb:U09564.1 AW082913 SRSF protein kinase 1 SRPK1 6732 NM_003137 /// NR_034069 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007059 // chromosome segregation // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035092 // sperm chromatin condensation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement /// 0050684 // regulation of mRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202200_s_at NM_003137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003137.1 /DEF=Homo sapiens SFRS protein kinase 1 (SRPK1), mRNA. /FEA=mRNA /GEN=SRPK1 /PROD=SFRS protein kinase 1 /DB_XREF=gi:4507218 /UG=Hs.75761 SFRS protein kinase 1 /FL=gb:NM_003137.1 gb:U09564.1 NM_003137 SRSF protein kinase 1 SRPK1 6732 NM_003137 /// NR_034069 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007059 // chromosome segregation // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035092 // sperm chromatin condensation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement /// 0050684 // regulation of mRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202201_at NM_000713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000713.1 /DEF=Homo sapiens biliverdin reductase B (flavin reductase (NADPH)) (BLVRB), mRNA. /FEA=mRNA /GEN=BLVRB /PROD=biliverdin reductase B (flavin reductase(NADPH)) /DB_XREF=gi:4502418 /UG=Hs.76289 biliverdin reductase B (flavin reductase (NADPH)) /FL=gb:D26308.1 gb:NM_000713.1 NM_000713 biliverdin reductase B (flavin reductase (NADPH)) BLVRB 645 NM_000713 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // inferred from direct assay /// 0042167 // heme catabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0004074 // biliverdin reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042602 // riboflavin reductase (NADPH) activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 202202_s_at NM_002290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002290.2 /DEF=Homo sapiens laminin, alpha 4 (LAMA4), mRNA. /FEA=mRNA /GEN=LAMA4 /PROD=laminin, alpha 4 precursor /DB_XREF=gi:9845494 /UG=Hs.78672 laminin, alpha 4 /FL=gb:NM_002290.2 NM_002290 laminin, alpha 4 LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202203_s_at NM_001144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001144.1 /DEF=Homo sapiens autocrine motility factor receptor (AMFR), mRNA. /FEA=mRNA /GEN=AMFR /PROD=autocrine motility factor receptor /DB_XREF=gi:4502074 /UG=Hs.80731 autocrine motility factor receptor /FL=gb:NM_001144.1 gb:L35233.1 gb:AF124145.1 NM_001144 autocrine motility factor receptor, E3 ubiquitin protein ligase AMFR 267 NM_001144 /// NM_138958 /// XM_005255889 /// XM_005255890 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202204_s_at AF124145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF124145.1 /DEF=Homo sapiens autocrine motility factor receptor (AMFR) mRNA, complete cds. /FEA=mRNA /GEN=AMFR /PROD=autocrine motility factor receptor /DB_XREF=gi:5931954 /UG=Hs.80731 autocrine motility factor receptor /FL=gb:NM_001144.1 gb:L35233.1 gb:AF124145.1 AF124145 autocrine motility factor receptor, E3 ubiquitin protein ligase AMFR 267 NM_001144 /// NM_138958 /// XM_005255889 /// XM_005255890 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202205_at NM_003370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003370.1 /DEF=Homo sapiens vasodilator-stimulated phosphoprotein (VASP), mRNA. /FEA=mRNA /GEN=VASP /PROD=vasodilator-stimulated phosphoprotein /DB_XREF=gi:4507868 /UG=Hs.93183 vasodilator-stimulated phosphoprotein /FL=gb:NM_003370.1 NM_003370 vasodilator-stimulated phosphoprotein VASP 7408 NM_001008736 /// NM_003370 /// XM_005259199 /// XM_005259200 0001843 // neural tube closure // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 202206_at AW450363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450363 /FEA=EST /DB_XREF=gi:6991139 /DB_XREF=est:UI-H-BI3-akn-d-02-0-UI.s1 /CLONE=IMAGE:2734875 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2 AW450363 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202207_at BG435404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG435404 /FEA=EST /DB_XREF=gi:13341910 /DB_XREF=est:602507678F1 /CLONE=IMAGE:4605066 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2 BG435404 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202208_s_at BC001051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001051.1 /DEF=Homo sapiens, ADP-ribosylation factor-like 7, clone MGC:1575, mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor-like 7 /DB_XREF=gi:12654450 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2 BC001051 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202209_at NM_014463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014463.1 /DEF=Homo sapiens Lsm3 protein (LSM3), mRNA. /FEA=mRNA /GEN=LSM3 /PROD=Lsm3 protein /DB_XREF=gi:7657314 /UG=Hs.111632 Lsm3 protein /FL=gb:AF182418.1 gb:AF182289.1 gb:NM_014463.1 NM_014463 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM3 27258 NM_014463 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202210_x_at NM_019884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019884.1 /DEF=Homo sapiens glycogen synthase kinase 3 alpha (GSK3A), mRNA. /FEA=mRNA /GEN=GSK3A /PROD=glycogen synthase kinase 3 alpha /DB_XREF=gi:11995473 /UG=Hs.118890 glycogen synthase kinase 3 alpha /FL=gb:NM_019884.1 gb:D63424.1 gb:L40027.1 NM_019884 glycogen synthase kinase 3 alpha GSK3A 2931 NM_019884 0003073 // regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010905 // negative regulation of UDP-glucose catabolic process // inferred by curator /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0036016 // cellular response to interleukin-3 // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // non-traceable author statement /// 0045823 // positive regulation of heart contraction // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051348 // negative regulation of transferase activity // inferred from mutant phenotype /// 0061052 // negative regulation of cell growth involved in cardiac muscle cell development // inferred from sequence or structural similarity /// 0071879 // positive regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2000077 // negative regulation of type B pancreatic cell development // traceable author statement /// 2000466 // negative regulation of glycogen (starch) synthase activity // traceable author statement /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement /// 0030877 // beta-catenin destruction complex // non-traceable author statement /// 0030877 // beta-catenin destruction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0050321 // tau-protein kinase activity // traceable author statement 202211_at BC005122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005122.1 /DEF=Homo sapiens, ADP-ribosylation factor GTPase activating protein 1, clone MGC:10272, mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor GTPase activatingprotein 1 /DB_XREF=gi:13477296 /UG=Hs.13014 ADP-ribosylation factor GTPase activating protein 1 /FL=gb:BC005122.1 gb:AF111847.1 gb:NM_014570.1 BC005122 ADP-ribosylation factor GTPase activating protein 3 ARFGAP3 26286 NM_001142293 /// NM_014570 /// XM_005261525 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0009306 // protein secretion // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202212_at NM_014303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014303.1 /DEF=Homo sapiens pescadillo (zebrafish) homolog 1, containing BRCT domain (PES1), mRNA. /FEA=mRNA /GEN=PES1 /PROD=pescadillo (zebrafish) homolog 1, containingBRCT domain /DB_XREF=gi:7657454 /UG=Hs.13501 pescadillo (zebrafish) homolog 1, containing BRCT domain /FL=gb:U78310.1 gb:NM_014303.1 NM_014303 pescadillo ribosomal biogenesis factor 1 PES1 23481 NM_001243225 /// NM_001282327 /// NM_001282328 /// NM_014303 /// XM_006724173 0000463 // maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0000466 // maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008283 // cell proliferation // non-traceable author statement /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042273 // ribosomal large subunit biogenesis // inferred by curator /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030687 // preribosome, large subunit precursor // inferred from direct assay /// 0070545 // PeBoW complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202213_s_at AI650819 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI650819 /FEA=EST /DB_XREF=gi:4734798 /DB_XREF=est:wa95a10.x1 /CLONE=IMAGE:2303898 /UG=Hs.155976 cullin 4B /FL=gb:NM_003588.1 gb:AB014595.1 AI650819 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 202214_s_at NM_003588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003588.1 /DEF=Homo sapiens cullin 4B (CUL4B), mRNA. /FEA=mRNA /GEN=CUL4B /PROD=cullin 4B /DB_XREF=gi:13270466 /UG=Hs.155976 cullin 4B /FL=gb:NM_003588.1 gb:AB014595.1 NM_003588 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 202215_s_at NM_014223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014223.2 /DEF=Homo sapiens nuclear transcription factor Y, gamma (NFYC), mRNA. /FEA=mRNA /GEN=NFYC /PROD=nuclear transcription factor Y, gamma /DB_XREF=gi:11496977 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:NM_014223.2 gb:D85425.1 gb:BC005003.1 gb:D89986.1 NM_014223 nuclear transcription factor Y, gamma NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202216_x_at BC005003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005003.1 /DEF=Homo sapiens, nuclear transcription factor Y, gamma, clone MGC:792, mRNA, complete cds. /FEA=mRNA /PROD=nuclear transcription factor Y, gamma /DB_XREF=gi:13436472 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:NM_014223.2 gb:D85425.1 gb:BC005003.1 gb:D89986.1 BC005003 nuclear transcription factor Y, gamma NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202217_at NM_004649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004649.1 /DEF=Homo sapiens ES1 (zebrafish) protein, human homolog of (C21ORF33), mRNA. /FEA=mRNA /GEN=C21ORF33 /PROD=ES1 (zebrafish) protein, human homolog of /DB_XREF=gi:5031690 /UG=Hs.182423 ES1 (zebrafish) protein, human homolog of /FL=gb:BC002370.1 gb:BC003587.1 gb:D86061.1 gb:U53003.1 gb:NM_004649.1 NM_004649 chromosome 21 open reading frame 33 C21orf33 8209 NM_004649 /// NM_198155 /// XM_005261184 /// XM_005261185 /// XM_005261186 /// XM_006724055 /// XM_006724056 0005739 // mitochondrion // not recorded 202218_s_at NM_004265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004265.1 /DEF=Homo sapiens delta-6 fatty acid desaturase (FADSD6), mRNA. /FEA=mRNA /GEN=FADSD6 /PROD=delta-6 fatty acid desaturase /DB_XREF=gi:4758333 /UG=Hs.184641 fatty acid desaturase 2 /FL=gb:AF084559.1 gb:AF126799.1 gb:NM_004265.1 NM_004265 fatty acid desaturase 2 FADS2 9415 NM_001281501 /// NM_001281502 /// NM_004265 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 202219_at NM_005629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005629.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), mRNA. /FEA=mRNA /GEN=SLC6A8 /PROD=solute carrier family 6 (neurotransmittertransporter, creatine), member 8 /DB_XREF=gi:5032096 /UG=Hs.187958 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 /FL=gb:L31409.1 gb:NM_005629.1 NM_005629 solute carrier family 6 (neurotransmitter transporter), member 8 SLC6A8 6535 NM_001142805 /// NM_001142806 /// NM_005629 0006600 // creatine metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0015871 // choline transport // inferred from electronic annotation /// 0015881 // creatine transport // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // non-traceable author statement /// 1902598 // creatine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005308 // creatine transmembrane transporter activity // non-traceable author statement /// 0005309 // creatine:sodium symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 202220_at NM_014949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014949.1 /DEF=Homo sapiens KIAA0907 protein (KIAA0907), mRNA. /FEA=mRNA /GEN=KIAA0907 /PROD=KIAA0907 protein /DB_XREF=gi:7662371 /UG=Hs.24656 KIAA0907 protein /FL=gb:AB020714.1 gb:NM_014949.1 NM_014949 KIAA0907 KIAA0907 22889 NM_014949 0003723 // RNA binding // inferred from electronic annotation 202221_s_at AV727101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV727101 /FEA=EST /DB_XREF=gi:10836522 /DB_XREF=est:AV727101 /CLONE=HTCBGF05 /UG=Hs.25272 E1A binding protein p300 /FL=gb:NM_001429.1 gb:U01877.1 AV727101 E1A binding protein p300 EP300 2033 NM_001429 /// XM_006724165 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0043969 // histone H2B acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0090043 // regulation of tubulin deacetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 202222_s_at NM_001927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001927.1 /DEF=Homo sapiens desmin (DES), mRNA. /FEA=mRNA /GEN=DES /PROD=desmin /DB_XREF=gi:4503306 /UG=Hs.279604 desmin /FL=gb:AF167579.1 gb:U59167.1 gb:AF055081.1 gb:AF055082.1 gb:AF055083.1 gb:NM_001927.1 gb:AF137053.1 NM_001927 desmin DES 1674 NM_001927 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202223_at NM_002219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002219.1 /DEF=Homo sapiens integral membrane protein 1 (ITM1), mRNA. /FEA=mRNA /GEN=ITM1 /PROD=integral membrane protein 1 /DB_XREF=gi:4504786 /UG=Hs.287850 integral membrane protein 1 /FL=gb:NM_002219.1 gb:L38961.1 NM_002219 STT3A, subunit of the oligosaccharyltransferase complex (catalytic) STT3A 3703 NM_001278503 /// NM_001278504 /// NM_152713 0006486 // protein glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043686 // co-translational protein modification // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004576 // oligosaccharyl transferase activity // inferred from electronic annotation /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from mutant phenotype /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 202224_at BF304695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF304695 /FEA=EST /DB_XREF=gi:11251580 /DB_XREF=est:601888248F1 /CLONE=IMAGE:4122466 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1 BF304695 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 202225_at AW612311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW612311 /FEA=EST /DB_XREF=gi:7317497 /DB_XREF=est:hg95e07.x1 /CLONE=IMAGE:2953380 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1 AW612311 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 202226_s_at NM_016823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016823.1 /DEF=Homo sapiens v-crk avian sarcoma virus CT10 oncogene homolog (CRK), transcript variant II, mRNA. /FEA=mRNA /GEN=CRK /PROD=v-crk avian sarcoma virus CT10 oncogene homologisoform a /DB_XREF=gi:8400705 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1 NM_016823 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 202227_s_at NM_006696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006696.1 /DEF=Homo sapiens thyroid hormone receptor coactivating protein (SMAP), mRNA. /FEA=mRNA /GEN=SMAP /PROD=thyroid hormone receptor coactivating protein /DB_XREF=gi:5730052 /UG=Hs.5464 thyroid hormone receptor coactivating protein /FL=gb:AF016270.1 gb:NM_006696.1 NM_006696 bromodomain containing 8 BRD8 10902 NM_001164326 /// NM_006696 /// NM_139199 /// NM_183359 /// XM_005271855 /// XM_005271856 /// XM_005271857 /// XM_005271859 /// XM_005271860 /// XM_005271861 /// XM_005271864 /// XM_005271865 /// XM_006714524 /// XM_006714525 /// XR_427701 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202228_s_at NM_017455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017455.1 /DEF=Homo sapiens stromal cell derived factor receptor 1 (SDFR1), transcript variant alpha, mRNA. /FEA=mRNA /GEN=SDFR1 /PROD=stromal cell derived factor receptor 1 isoforma /DB_XREF=gi:9257239 /UG=Hs.6354 stromal cell derived factor receptor 1 /FL=gb:AF109127.1 gb:NM_017455.1 NM_017455 neuroplastin NPTN 27020 NM_001161363 /// NM_001161364 /// NM_012428 /// NM_017455 /// XM_005254304 /// XR_429449 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity 0005105 // type 1 fibroblast growth factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 202229_s_at AI372979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI372979 /FEA=EST /DB_XREF=gi:4152845 /DB_XREF=est:qz17g05.x1 /CLONE=IMAGE:2021816 /UG=Hs.6430 protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein /FL=gb:U94836.2 gb:NM_006387.2 AI372979 calcium homeostasis endoplasmic reticulum protein CHERP 10523 NM_006387 0006396 // RNA processing // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202230_s_at NM_006387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006387.2 /DEF=Homo sapiens protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein (ERPROT213-21), mRNA. /FEA=mRNA /GEN=ERPROT213-21 /PROD=protein with polyglutamine repeat; calcium(ca2+) homeostasis endoplasmic reticulum protein /DB_XREF=gi:11055968 /UG=Hs.6430 protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein /FL=gb:U94836.2 gb:NM_006387.2 NM_006387 calcium homeostasis endoplasmic reticulum protein CHERP 10523 NM_006387 0006396 // RNA processing // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202231_at NM_006360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006360.1 /DEF=Homo sapiens dendritic cell protein (GA17), mRNA. /FEA=mRNA /GEN=GA17 /PROD=dendritic cell protein /DB_XREF=gi:5453653 /UG=Hs.69469 dendritic cell protein /FL=gb:AF277183.1 gb:AF064603.1 gb:NM_006360.1 NM_006360 eukaryotic translation initiation factor 3, subunit M EIF3M 10480 NM_006360 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0002183 // cytoplasmic translational initiation // not recorded /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 202232_s_at NM_006360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006360.1 /DEF=Homo sapiens dendritic cell protein (GA17), mRNA. /FEA=mRNA /GEN=GA17 /PROD=dendritic cell protein /DB_XREF=gi:5453653 /UG=Hs.69469 dendritic cell protein /FL=gb:AF277183.1 gb:AF064603.1 gb:NM_006360.1 NM_006360 eukaryotic translation initiation factor 3, subunit M EIF3M 10480 NM_006360 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0002183 // cytoplasmic translational initiation // not recorded /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202233_s_at NM_006004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006004.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase hinge protein (UQCRH), mRNA. /FEA=mRNA /GEN=UQCRH /PROD=ubiquinol-cytochrome c reductase hinge protein /DB_XREF=gi:5174744 /UG=Hs.73818 ubiquinol-cytochrome c reductase hinge protein /FL=gb:BC001426.1 gb:BC001934.1 gb:M36647.1 gb:NM_006004.1 NM_006004 ubiquinol-cytochrome c reductase hinge protein /// ubiquinol-cytochrome c reductase hinge protein-like UQCRH /// UQCRHL 7388 /// 440567 NM_001089591 /// NM_006004 /// XM_005271167 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // not recorded /// 0007266 // Rho protein signal transduction // /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030168 // platelet activation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // not recorded /// 0031584 // activation of phospholipase D activity // /// 0031584 // activation of phospholipase D activity // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031526 // brush border membrane // not recorded /// 0031526 // brush border membrane // /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // /// 0003924 // GTPase activity // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // not recorded /// 0031702 // type 1 angiotensin receptor binding // /// 0031752 // D5 dopamine receptor binding // not recorded /// 0031752 // D5 dopamine receptor binding // /// 0031752 // D5 dopamine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202234_s_at BF511091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511091 /FEA=EST /DB_XREF=gi:11594389 /DB_XREF=est:UI-H-BI4-apn-c-05-0-UI.s1 /CLONE=IMAGE:3087753 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1 BF511091 solute carrier family 16 (monocarboxylate transporter), member 1 SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202235_at BF511091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511091 /FEA=EST /DB_XREF=gi:11594389 /DB_XREF=est:UI-H-BI4-apn-c-05-0-UI.s1 /CLONE=IMAGE:3087753 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1 BF511091 solute carrier family 16 (monocarboxylate transporter), member 1 SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202236_s_at NM_003051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003051.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 1 (SLC16A1), mRNA. /FEA=mRNA /GEN=SLC16A1 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 1 /DB_XREF=gi:4506982 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1 NM_003051 solute carrier family 16 (monocarboxylate transporter), member 1 SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202237_at NM_006169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006169.1 /DEF=Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. /FEA=mRNA /GEN=NNMT /PROD=nicotinamide N-methyltransferase /DB_XREF=gi:5453789 /UG=Hs.76669 nicotinamide N-methyltransferase /FL=gb:BC000234.1 gb:U08021.1 gb:NM_006169.1 NM_006169 uncharacterized LOC101928916 /// nicotinamide N-methyltransferase LOC101928916 /// NNMT 4837 /// 101928916 NM_006169 /// XR_246479 /// XR_247717 /// XR_252975 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0008112 // nicotinamide N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202238_s_at NM_006169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006169.1 /DEF=Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. /FEA=mRNA /GEN=NNMT /PROD=nicotinamide N-methyltransferase /DB_XREF=gi:5453789 /UG=Hs.76669 nicotinamide N-methyltransferase /FL=gb:BC000234.1 gb:U08021.1 gb:NM_006169.1 NM_006169 uncharacterized LOC101928916 /// nicotinamide N-methyltransferase LOC101928916 /// NNMT 4837 /// 101928916 NM_006169 /// XR_246479 /// XR_247717 /// XR_252975 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0008112 // nicotinamide N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202239_at NM_006437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006437.2 /DEF=Homo sapiens ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 (ADPRTL1), mRNA. /FEA=mRNA /GEN=ADPRTL1 /PROD=poly(ADP-ribosyl)transferase-like 1 /DB_XREF=gi:11496990 /UG=Hs.77225 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 /FL=gb:NM_006437.2 gb:AF057160.1 gb:AF158255.1 NM_006437 poly (ADP-ribose) polymerase family, member 4 PARP4 143 NM_006437 0006281 // DNA repair // non-traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006471 // protein ADP-ribosylation // non-traceable author statement /// 0006810 // transport // non-traceable author statement /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement /// 0008219 // cell death // inferred from mutant phenotype /// 0042493 // response to drug // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay 202240_at NM_005030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005030.1 /DEF=Homo sapiens polo (Drosophia)-like kinase (PLK), mRNA. /FEA=mRNA /GEN=PLK /PROD=polo (Drosophia)-like kinase /DB_XREF=gi:4826915 /UG=Hs.77597 polo (Drosophia)-like kinase /FL=gb:BC002369.1 gb:BC003002.1 gb:U01038.1 gb:L19559.1 gb:NM_005030.1 NM_005030 polo-like kinase 1 PLK1 5347 NM_005030 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000281 // mitotic cytokinesis // inferred from direct assay /// 0000910 // cytokinesis // inferred from direct assay /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001578 // microtubule bundle formation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // traceable author statement /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008283 // cell proliferation // traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0040038 // polar body extrusion after meiotic divisions // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // traceable author statement /// 0071168 // protein localization to chromatin // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0000942 // condensed nuclear chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 202241_at NM_025195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025195.1 /DEF=Homo sapiens phosphoprotein regulated by mitogenic pathways (C8FW), mRNA. /FEA=mRNA /GEN=C8FW /PROD=G-protein-coupled receptor induced protein /DB_XREF=gi:13399327 /UG=Hs.7837 phosphoprotein regulated by mitogenic pathways /FL=gb:AF205437.1 gb:NM_025195.1 NM_025195 tribbles pseudokinase 1 TRIB1 10221 NM_001282985 /// NM_025195 /// XM_006716496 /// XM_006716497 /// XR_428373 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007254 // JNK cascade // inferred from mutant phenotype /// 0014912 // negative regulation of smooth muscle cell migration // inferred from mutant phenotype /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004672 // protein kinase activity // traceable author statement /// 0004860 // protein kinase inhibitor activity // inferred from mutant phenotype /// 0005524 // ATP binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity 202242_at NM_004615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004615.1 /DEF=Homo sapiens transmembrane 4 superfamily member 2 (TM4SF2), mRNA. /FEA=mRNA /GEN=TM4SF2 /PROD=transmembrane 4 superfamily member 2 /DB_XREF=gi:4759235 /UG=Hs.82749 transmembrane 4 superfamily member 2 /FL=gb:D10653.1 gb:D29808.1 gb:NM_004615.1 NM_004615 tetraspanin 7 TSPAN7 7102 NM_004615 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202243_s_at NM_002796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002796.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA. /FEA=mRNA /GEN=PSMB4 /PROD=proteasome (prosome, macropain) subunit, betatype, 4 /DB_XREF=gi:4506198 /UG=Hs.89545 proteasome (prosome, macropain) subunit, beta type, 4 /FL=gb:BC000331.1 gb:NM_002796.1 gb:D26600.1 NM_002796 proteasome (prosome, macropain) subunit, beta type, 4 PSMB4 5692 NM_002796 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202244_at NM_002796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002796.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA. /FEA=mRNA /GEN=PSMB4 /PROD=proteasome (prosome, macropain) subunit, betatype, 4 /DB_XREF=gi:4506198 /UG=Hs.89545 proteasome (prosome, macropain) subunit, beta type, 4 /FL=gb:BC000331.1 gb:NM_002796.1 gb:D26600.1 NM_002796 proteasome (prosome, macropain) subunit, beta type, 4 PSMB4 5692 NM_002796 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202245_at AW084510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW084510 /FEA=EST /DB_XREF=gi:6039662 /DB_XREF=est:wz24g11.x1 /CLONE=IMAGE:2559044 /UG=Hs.93199 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) /FL=gb:NM_002340.1 gb:U22526.1 AW084510 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) LSS 4047 NM_001001438 /// NM_001145436 /// NM_001145437 /// NM_002340 /// XM_006724003 /// XM_006724004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000250 // lanosterol synthase activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation 202246_s_at NM_000075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000075.1 /DEF=Homo sapiens cyclin-dependent kinase 4 (CDK4), mRNA. /FEA=mRNA /GEN=CDK4 /PROD=cyclin-dependent kinase 4 /DB_XREF=gi:4502734 /UG=Hs.95577 cyclin-dependent kinase 4 /FL=gb:BC003644.1 gb:U79269.1 gb:NM_000075.1 gb:M14505.1 NM_000075 cyclin-dependent kinase 4 CDK4 1019 NM_000075 /// NM_052984 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from genetic interaction /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202247_s_at BE561596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE561596 /FEA=EST /DB_XREF=gi:9805316 /DB_XREF=est:601347512F1 /CLONE=IMAGE:3688347 /UG=Hs.101448 metastasis associated 1 /FL=gb:U35113.1 gb:NM_004689.1 BE561596 metastasis associated 1 MTA1 9112 NM_001203258 /// NM_004689 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0033363 // secretory granule organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202248_at BC000110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000110.1 /DEF=Homo sapiens, Similar to E2F transcription factor 5, clone MGC:1262, mRNA, complete cds. /FEA=mRNA /PROD=Similar to E2F transcription factor 5 /DB_XREF=gi:12652720 /UG=Hs.108371 E2F transcription factor 4, p107p130-binding /FL=gb:BC000110.1 gb:NM_001950.2 gb:U15641.1 BC000110 E2F transcription factor 4, p107/p130-binding E2F4 1874 NM_001950 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008015 // blood circulation // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202249_s_at AU146233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146233 /FEA=EST /DB_XREF=gi:11007754 /DB_XREF=est:AU146233 /CLONE=HEMBA1007223 /UG=Hs.110707 H326 /FL=gb:U06631.1 gb:NM_015726.1 AU146233 DDB1 and CUL4 associated factor 8 DCAF8 50717 NM_015726 /// NR_028103 /// NR_028104 /// NR_028105 /// NR_028106 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202250_s_at NM_015726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015726.1 /DEF=Homo sapiens H326 (H326), mRNA. /FEA=mRNA /GEN=H326 /PROD=H326 /DB_XREF=gi:7657147 /UG=Hs.110707 H326 /FL=gb:U06631.1 gb:NM_015726.1 NM_015726 DDB1 and CUL4 associated factor 8 DCAF8 50717 NM_015726 /// NR_028103 /// NR_028104 /// NR_028105 /// NR_028106 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202251_at NM_004698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004698.1 /DEF=Homo sapiens U4U6-associated RNA splicing factor (HPRP3P), mRNA. /FEA=mRNA /GEN=HPRP3P /PROD=U4U6-associated RNA splicing factor /DB_XREF=gi:4758555 /UG=Hs.11776 U4U6-associated RNA splicing factor /FL=gb:BC000184.1 gb:BC001954.1 gb:AF016370.1 gb:AF001947.1 gb:NM_004698.1 NM_004698 pre-mRNA processing factor 3 PRPF3 9129 NM_004698 /// XR_241103 /// XR_241104 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202252_at NM_002870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002870.1 /DEF=Homo sapiens RAB13, member RAS oncogene family (RAB13), mRNA. /FEA=mRNA /GEN=RAB13 /PROD=RAB13, member RAS oncogene family /DB_XREF=gi:4506362 /UG=Hs.151536 RAB13, member RAS oncogene family /FL=gb:BC000799.1 gb:NM_002870.1 NM_002870 RAB13, member RAS oncogene family RAB13 5872 NM_001272038 /// NM_002870 /// NR_073553 0006184 // GTP catabolic process // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010737 // protein kinase A signaling // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035767 // endothelial cell chemotaxis // inferred from sequence or structural similarity /// 0044795 // trans-Golgi network to recycling endosome transport // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0070830 // tight junction assembly // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097368 // establishment of Sertoli cell barrier // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from electronic annotation 202253_s_at NM_004945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004945.1 /DEF=Homo sapiens dynamin 2 (DNM2), mRNA. /FEA=mRNA /GEN=DNM2 /PROD=dynamin 2 /DB_XREF=gi:4826699 /UG=Hs.167013 dynamin 2 /FL=gb:L36983.1 gb:NM_004945.1 NM_004945 dynamin 2 DNM2 1785 NM_001005360 /// NM_001005361 /// NM_001005362 /// NM_001190716 /// NM_004945 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048489 // synaptic vesicle transport // non-traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0045334 // clathrin-coated endocytic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 202254_at AB007900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007900.1 /DEF=Homo sapiens KIAA0440 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0440 /DB_XREF=gi:2662160 /UG=Hs.172180 KIAA0440 protein /FL=gb:AF090990.1 gb:NM_015556.1 AB007900 signal-induced proliferation-associated 1 like 1 SIPA1L1 26037 NM_001284245 /// NM_001284246 /// NM_001284247 /// NM_015556 /// XM_005267514 /// XM_005267516 /// XM_005267519 /// XM_006720109 /// XM_006720110 /// XM_006720111 /// XM_006720112 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032317 // regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0032861 // activation of Rap GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation 202255_s_at NM_015556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015556.1 /DEF=Homo sapiens KIAA0440 protein (KIAA0440), mRNA. /FEA=mRNA /GEN=KIAA0440 /PROD=KIAA0440 protein /DB_XREF=gi:7662125 /UG=Hs.172180 KIAA0440 protein /FL=gb:AF090990.1 gb:NM_015556.1 NM_015556 signal-induced proliferation-associated 1 like 1 SIPA1L1 26037 NM_001284245 /// NM_001284246 /// NM_001284247 /// NM_015556 /// XM_005267514 /// XM_005267516 /// XM_005267519 /// XM_006720109 /// XM_006720110 /// XM_006720111 /// XM_006720112 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032317 // regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0032861 // activation of Rap GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation 202256_at BF793888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF793888 /FEA=EST /DB_XREF=gi:12098942 /DB_XREF=est:602255284F1 /CLONE=IMAGE:4347332 /UG=Hs.202677 CD2 antigen (cytoplasmic tail)-binding protein 2 /FL=gb:BC000495.1 gb:BC001947.1 gb:AF104222.1 gb:NM_006110.1 BF793888 CD2 (cytoplasmic tail) binding protein 2 CD2BP2 10421 NM_001243646 /// NM_006110 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 202257_s_at NM_006110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006110.1 /DEF=Homo sapiens CD2 antigen (cytoplasmic tail)-binding protein 2 (CD2BP2), mRNA. /FEA=mRNA /GEN=CD2BP2 /PROD=CD2 antigen (cytoplasmic tail)-binding protein2 /DB_XREF=gi:5174408 /UG=Hs.202677 CD2 antigen (cytoplasmic tail)-binding protein 2 /FL=gb:BC000495.1 gb:BC001947.1 gb:AF104222.1 gb:NM_006110.1 NM_006110 CD2 (cytoplasmic tail) binding protein 2 CD2BP2 10421 NM_001243646 /// NM_006110 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 202258_s_at U50532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U50532.1 /DEF=Human BRCA2 region, mRNA sequence CG005. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1531603 /UG=Hs.23518 hypothetical protein from BCRA2 region /FL=gb:NM_014887.1 U50532 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 202259_s_at NM_014887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014887.1 /DEF=Homo sapiens hypothetical protein from BCRA2 region (CG005), mRNA. /FEA=mRNA /GEN=CG005 /PROD=hypothetical protein from BCRA2 region /DB_XREF=gi:7656970 /UG=Hs.23518 hypothetical protein from BCRA2 region /FL=gb:NM_014887.1 NM_014887 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 202260_s_at NM_003165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003165.1 /DEF=Homo sapiens syntaxin binding protein 1 (STXBP1), mRNA. /FEA=mRNA /GEN=STXBP1 /PROD=syntaxin binding protein 1 /DB_XREF=gi:4507296 /UG=Hs.239356 syntaxin binding protein 1 /FL=gb:AF004563.1 gb:NM_003165.1 NM_003165 syntaxin binding protein 1 STXBP1 6812 NM_001032221 /// NM_003165 0002576 // platelet degranulation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from sequence or structural similarity /// 0010807 // regulation of synaptic vesicle priming // inferred from sequence or structural similarity /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050821 // protein stabilization // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031091 // platelet alpha granule // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation 202261_at NM_005997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005997.1 /DEF=Homo sapiens transcription factor-like 1 (TCFL1), mRNA. /FEA=mRNA /GEN=TCFL1 /PROD=transcription factor-like 1 /DB_XREF=gi:5174714 /UG=Hs.2430 transcription factor-like 1 /FL=gb:BC003151.1 gb:NM_005997.1 gb:D43642.1 NM_005997 vacuolar protein sorting 72 homolog (S. cerevisiae) VPS72 6944 NM_001271087 /// NM_001271088 /// NM_005997 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202262_x_at NM_013974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013974.1 /DEF=Homo sapiens dimethylarginine dimethylaminohydrolase 2 (DDAH2), mRNA. /FEA=mRNA /GEN=DDAH2 /PROD=dimethylarginine dimethylaminohydrolase 2 /DB_XREF=gi:7524353 /UG=Hs.247362 dimethylarginine dimethylaminohydrolase 2 /FL=gb:BC001435.1 gb:AF070667.1 gb:NM_013974.1 NM_013974 dimethylarginine dimethylaminohydrolase 2 DDAH2 23564 NM_013974 /// XM_005248974 /// XM_005272783 /// XM_005274929 /// XM_005275086 /// XM_005275225 /// XM_005275361 /// XM_005275522 0000052 // citrulline metabolic process // inferred from direct assay /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016403 // dimethylargininase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation 202263_at NM_016243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016243.1 /DEF=Homo sapiens cytochrome b5 reductase 1 (B5R.1) (LOC51706), mRNA. /FEA=mRNA /GEN=LOC51706 /PROD=cytochrome b5 reductase 1 (B5R.1) /DB_XREF=gi:7706454 /UG=Hs.289113 cytochrome b5 reductase 1 (B5R.1) /FL=gb:AF169481.1 gb:AF125533.1 gb:NM_016243.1 NM_016243 cytochrome b5 reductase 1 CYB5R1 51706 NM_016243 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 202264_s_at NM_006114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006114.1 /DEF=Homo sapiens DNA segment on chromosome 19 (unique) 1177 expressed sequence (D19S1177E), mRNA. /FEA=mRNA /GEN=D19S1177E /PROD=mitochondrial outer membrane protein TOM40 /DB_XREF=gi:5174722 /UG=Hs.30928 DNA segment on chromosome 19 (unique) 1177 expressed sequence /FL=gb:BC001779.1 gb:AF043250.1 gb:NM_006114.1 NM_006114 translocase of outer mitochondrial membrane 40 homolog (yeast) TOMM40 10452 NM_001128916 /// NM_001128917 /// NM_006114 /// XM_005258411 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071806 // protein transmembrane transport // inferred from sequence or structural similarity /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from mutant phenotype /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008320 // protein transmembrane transporter activity // inferred from sequence or structural similarity /// 0008320 // protein transmembrane transporter activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 202265_at NM_005180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005180.1 /DEF=Homo sapiens murine leukemia viral (bmi-1) oncogene homolog (BMI1), mRNA. /FEA=mRNA /GEN=BMI1 /PROD=murine leukemia viral (bmi-1) oncogene homolog /DB_XREF=gi:4885094 /UG=Hs.431 murine leukemia viral (bmi-1) oncogene homolog /FL=gb:L13689.1 gb:NM_005180.1 NM_005180 BMI1 proto-oncogene, polycomb ring finger /// COMMD3-BMI1 readthrough BMI1 /// COMMD3-BMI1 648 /// 100532731 NM_001204062 /// NM_005180 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007379 // segment specification // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from expression pattern /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 202266_at NM_016614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016614.1 /DEF=Homo sapiens TRAF and TNF receptor-associated protein (AD022), mRNA. /FEA=mRNA /GEN=AD022 /PROD=TRAF and TNF receptor-associated protein /DB_XREF=gi:7705261 /UG=Hs.46847 TRAF and TNF receptor-associated protein /FL=gb:AF201687.1 gb:AF223469.1 gb:NM_016614.1 NM_016614 tyrosyl-DNA phosphodiesterase 2 TDP2 51567 NM_016614 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0036317 // tyrosyl-RNA phosphodiesterase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070260 // 5'-tyrosyl-DNA phosphodiesterase activity // inferred from direct assay /// 0070260 // 5'-tyrosyl-DNA phosphodiesterase activity // inferred from mutant phenotype 202267_at NM_005562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005562.1 /DEF=Homo sapiens laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) (LAMC2), transcript variant 1, mRNA. /FEA=mRNA /GEN=LAMC2 /PROD=laminin, gamma 2, isoform a precursor /DB_XREF=gi:5031846 /UG=Hs.54451 laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) /FL=gb:NM_005562.1 NM_005562 laminin, gamma 2 LAMC2 3918 NM_005562 /// NM_018891 /// XM_005245150 /// XM_006711316 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005607 // laminin-2 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 202268_s_at NM_003905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003905.1 /DEF=Homo sapiens amyloid beta precursor protein-binding protein 1, 59kD (APPBP1), mRNA. /FEA=mRNA /GEN=APPBP1 /PROD=Amyloid beta precursor protein-binding protein1 /DB_XREF=gi:4502168 /UG=Hs.61828 amyloid beta precursor protein-binding protein 1, 59kD /FL=gb:AL136798.1 gb:BC000480.1 gb:U50939.1 gb:NM_003905.1 NM_003905 NEDD8 activating enzyme E1 subunit 1 NAE1 8883 NM_001018159 /// NM_001018160 /// NM_001286500 /// NM_003905 /// XM_005256215 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033314 // mitotic DNA replication checkpoint // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043523 // regulation of neuron apoptotic process // inferred from direct assay /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019781 // NEDD8 activating enzyme activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 202269_x_at BC002666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002666.1 /DEF=Homo sapiens, guanylate binding protein 1, interferon-inducible, 67kD, clone MGC:3949, mRNA, complete cds. /FEA=mRNA /PROD=guanylate binding protein 1,interferon-inducible, 67kD /DB_XREF=gi:12803662 /UG=Hs.62661 guanylate binding protein 1, interferon-inducible, 67kD /FL=gb:BC002666.1 gb:M55542.1 gb:NM_002053.1 BC002666 guanylate binding protein 1, interferon-inducible GBP1 2633 NM_002053 /// XM_006710573 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202270_at NM_002053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002053.1 /DEF=Homo sapiens guanylate binding protein 1, interferon-inducible, 67kD (GBP1), mRNA. /FEA=mRNA /GEN=GBP1 /PROD=guanylate binding protein 1,interferon-inducible, 67kD /DB_XREF=gi:4503938 /UG=Hs.62661 guanylate binding protein 1, interferon-inducible, 67kD /FL=gb:BC002666.1 gb:M55542.1 gb:NM_002053.1 NM_002053 guanylate binding protein 1, interferon-inducible GBP1 2633 NM_002053 /// XM_006710573 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202271_at AB007952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007952.1 /DEF=Homo sapiens mRNA for KIAA0483 protein, partial cds. /FEA=mRNA /GEN=KIAA0483 /PROD=KIAA0483 protein /DB_XREF=gi:3413925 /UG=Hs.64691 KIAA0483 protein /FL=gb:NM_015176.1 AB007952 F-box protein 28 FBXO28 23219 NM_001136115 /// NM_015176 /// NR_049764 0005515 // protein binding // inferred from electronic annotation 202272_s_at NM_015176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015176.1 /DEF=Homo sapiens KIAA0483 protein (KIAA0483), mRNA. /FEA=mRNA /GEN=KIAA0483 /PROD=KIAA0483 protein /DB_XREF=gi:7662157 /UG=Hs.64691 KIAA0483 protein /FL=gb:NM_015176.1 NM_015176 F-box protein 28 FBXO28 23219 NM_001136115 /// NM_015176 /// NR_049764 0005515 // protein binding // inferred from electronic annotation 202273_at NM_002609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002609.1 /DEF=Homo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB), mRNA. /FEA=mRNA /GEN=PDGFRB /PROD=platelet-derived growth factor receptor, betapolypeptide /DB_XREF=gi:4505682 /UG=Hs.76144 platelet-derived growth factor receptor, beta polypeptide /FL=gb:M21616.1 gb:J03278.1 gb:NM_002609.1 NM_002609 platelet-derived growth factor receptor, beta polypeptide PDGFRB 5159 NM_002609 /// XM_005268464 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006024 // glycosaminoglycan biosynthetic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from mutant phenotype /// 0014911 // positive regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from electronic annotation /// 0035441 // cell migration involved in vasculogenesis // inferred from sequence or structural similarity /// 0035789 // metanephric mesenchymal cell migration // inferred from electronic annotation /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036120 // cellular response to platelet-derived growth factor stimulus // traceable author statement /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060981 // cell migration involved in coronary angiogenesis // inferred from sequence or structural similarity /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071670 // smooth muscle cell chemotaxis // inferred from sequence or structural similarity /// 0072075 // metanephric mesenchyme development // inferred from electronic annotation /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072275 // metanephric glomerulus morphogenesis // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from electronic annotation /// 0072284 // metanephric S-shaped body morphogenesis // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004992 // platelet activating factor receptor activity // traceable author statement /// 0005017 // platelet-derived growth factor-activated receptor activity // traceable author statement /// 0005019 // platelet-derived growth factor beta-receptor activity // inferred from direct assay /// 0005019 // platelet-derived growth factor beta-receptor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 202274_at NM_001615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001615.2 /DEF=Homo sapiens actin, gamma 2, smooth muscle, enteric (ACTG2), mRNA. /FEA=mRNA /GEN=ACTG2 /PROD=actin, gamma 2 propeptide /DB_XREF=gi:11038625 /UG=Hs.78045 actin, gamma 2, smooth muscle, enteric /FL=gb:NM_001615.2 NM_001615 actin, gamma 2, smooth muscle, enteric ACTG2 72 NM_001199893 /// NM_001615 0006936 // muscle contraction // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202275_at NM_000402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000402.1 /DEF=Homo sapiens glucose-6-phosphate dehydrogenase (G6PD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=G6PD /PROD=glucose-6-phosphate dehydrogenase /DB_XREF=gi:4503844 /UG=Hs.80206 glucose-6-phosphate dehydrogenase /FL=gb:BC000337.1 gb:M21248.1 gb:NM_000402.1 NM_000402 glucose-6-phosphate dehydrogenase G6PD 2539 NM_000402 /// NM_001042351 /// XM_005274657 /// XM_005274658 0001816 // cytokine production // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006739 // NADP metabolic process // inferred from direct assay /// 0006740 // NADPH regeneration // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from mutant phenotype /// 0010734 // negative regulation of protein glutathionylation // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019322 // pentose biosynthetic process // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032094 // response to food // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0043249 // erythrocyte maturation // inferred from mutant phenotype /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046390 // ribose phosphate biosynthetic process // inferred from mutant phenotype /// 0051156 // glucose 6-phosphate metabolic process // inferred from direct assay /// 0051156 // glucose 6-phosphate metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from direct assay /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from direct assay /// 0005536 // glucose binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050661 // NADP binding // inferred from direct assay 202276_at NM_006304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006304.1 /DEF=Homo sapiens Deleted in split-handsplit-foot 1 region (DSS1), mRNA. /FEA=mRNA /GEN=DSS1 /PROD=deleted in split-handsplit-foot 1 region /DB_XREF=gi:5453639 /UG=Hs.85215 Deleted in split-handsplit-foot 1 region /FL=gb:U41515.1 gb:NM_006304.1 NM_006304 split hand/foot malformation (ectrodactyly) type 1 SHFM1 7979 NM_006304 0000724 // double-strand break repair via homologous recombination // not recorded /// 0006508 // proteolysis // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay 202277_at AL568804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568804 /FEA=EST /DB_XREF=gi:12923509 /DB_XREF=est:AL568804 /CLONE=CS0DE005YN15 (3 prime) /UG=Hs.90458 serine palmitoyltransferase, long chain base subunit 1 /FL=gb:NM_006415.1 AL568804 serine palmitoyltransferase, long chain base subunit 1 SPTLC1 10558 NM_001281303 /// NM_006415 /// NM_178324 /// XR_242563 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay /// 0035339 // SPOTS complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 202278_s_at NM_006415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006415.1 /DEF=Homo sapiens serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), mRNA. /FEA=mRNA /GEN=SPTLC1 /PROD=serine palmitoyltransferase, long chain basesubunit 1 /DB_XREF=gi:5454083 /UG=Hs.90458 serine palmitoyltransferase, long chain base subunit 1 /FL=gb:NM_006415.1 NM_006415 serine palmitoyltransferase, long chain base subunit 1 SPTLC1 10558 NM_001281303 /// NM_006415 /// NM_178324 /// XR_242563 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay /// 0035339 // SPOTS complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 202279_at NM_004894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004894.1 /DEF=Homo sapiens chromosome 14 open reading frame 2 (C14ORF2), mRNA. /FEA=mRNA /GEN=C14ORF2 /PROD=chromosome 14 open reading frame 2 /DB_XREF=gi:4758939 /UG=Hs.109052 chromosome 14 open reading frame 2 /FL=gb:BC000429.1 gb:BC001944.1 gb:AF054175.1 gb:NM_004894.1 NM_004894 chromosome 14 open reading frame 2 C14orf2 9556 NM_001127393 /// NM_004894 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 202280_at D88435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D88435.1 /DEF=Homo sapiens mRNA for HsGAK, complete cds. /FEA=mRNA /PROD=HsGAK /DB_XREF=gi:2506079 /UG=Hs.153227 cyclin G associated kinase /FL=gb:D88435.1 gb:NM_005255.1 D88435 202281_at NM_005255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005255.1 /DEF=Homo sapiens cyclin G associated kinase (GAK), mRNA. /FEA=mRNA /GEN=GAK /PROD=cyclin G associated kinase /DB_XREF=gi:4885250 /UG=Hs.153227 cyclin G associated kinase /FL=gb:D88435.1 gb:NM_005255.1 NM_005255 cyclin G associated kinase GAK 2580 NM_001286833 /// NM_005255 /// XM_005272268 /// XM_005272269 /// XM_005272270 /// XM_005272272 /// XM_005272273 /// XM_006713874 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202282_at NM_004493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004493.1 /DEF=Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase, type II (HADH2), mRNA. /FEA=mRNA /GEN=HADH2 /PROD=hydroxyacyl-Coenzyme A dehydrogenase, type II /DB_XREF=gi:4758503 /UG=Hs.171280 hydroxyacyl-Coenzyme A dehydrogenase, type II /FL=gb:BC000372.1 gb:BC000829.1 gb:U73514.1 gb:U96132.1 gb:AF035555.1 gb:AF069134.1 gb:NM_004493.1 NM_004493 hydroxysteroid (17-beta) dehydrogenase 10 HSD17B10 3028 NM_001037811 /// NM_004493 0006629 // lipid metabolic process // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008709 // cholate 7-alpha-dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030283 // testosterone dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047015 // 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity // inferred from electronic annotation 202283_at NM_002615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002615.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1), mRNA. /FEA=mRNA /GEN=SERPINF1 /PROD=serine (or cysteine) proteinase inhibitor, cladeF (alpha-2 antiplasmin, pigment epithelium derivedfactor), member 1 /DB_XREF=gi:4505708 /UG=Hs.173594 serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 /FL=gb:M90439.1 gb:BC000522.1 gb:M76979.1 gb:NM_002615.1 NM_002615 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 SERPINF1 5176 NM_002615 0001822 // kidney development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007614 // short-term memory // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030162 // regulation of proteolysis // not recorded /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded 202284_s_at NM_000389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000389.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), mRNA. /FEA=mRNA /GEN=CDKN1A /PROD=cyclin-dependent kinase inhibitor 1A (p21,Cip1) /DB_XREF=gi:11386202 /UG=Hs.179665 cyclin-dependent kinase inhibitor 1A (p21, Cip1) /FL=gb:NM_000389.1 gb:BC000275.1 gb:BC001935.1 gb:U03106.1 gb:L26165.1 gb:L25610.1 gb:U09579.1 NM_000389 cyclin-dependent kinase inhibitor 1A (p21, Cip1) CDKN1A 1026 NM_000389 /// NM_001220777 /// NM_001220778 /// NM_001291549 /// NM_078467 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from expression pattern /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from mutant phenotype /// 0033158 // regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 0090400 // stress-induced premature senescence // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2000278 // regulation of DNA biosynthetic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070557 // PCNA-p21 complex // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019912 // cyclin-dependent protein kinase activating kinase activity // inferred from direct assay /// 0030332 // cyclin binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202285_s_at AI627697 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI627697 /FEA=EST /DB_XREF=gi:4664497 /DB_XREF=est:ty81g09.x1 /CLONE=IMAGE:2285536 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1 AI627697 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202286_s_at J04152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J04152 /DEF=Human gastrointestinal tumor-associated antigen GA733-1 protein gene, complete cds, clone 05516 /FEA=mRNA /DB_XREF=gi:182893 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1 J04152 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 202287_s_at NM_002353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002353.1 /DEF=Homo sapiens tumor-associated calcium signal transducer 2 (TACSTD2), mRNA. /FEA=mRNA /GEN=TACSTD2 /PROD=tumor-associated calcium signal transducer 2precursor /DB_XREF=gi:4505056 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1 NM_002353 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202288_at U88966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88966.1 /DEF=Human protein rapamycin associated protein (FRAP2) gene, complete cds. /FEA=mRNA /GEN=FRAP2 /PROD=rapamycin associated protein FRAP2 /DB_XREF=gi:3282238 /UG=Hs.250723 FK506 binding protein 12-rapamycin associated protein 1 /FL=gb:U88966.1 gb:NM_004958.1 gb:L34075.1 U88966 mechanistic target of rapamycin (serine/threonine kinase) MTOR 2475 NM_004958 /// XM_005263438 /// XM_005263439 /// XR_244786 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0006109 // regulation of carbohydrate metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006950 // response to stress // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007584 // response to nutrient // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010507 // negative regulation of autophagy // inferred from sequence or structural similarity /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016049 // cell growth // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030163 // protein catabolic process // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0031998 // regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032095 // regulation of response to food // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040007 // growth // non-traceable author statement /// 0043200 // response to amino acid // inferred from direct assay /// 0043610 // regulation of carbohydrate utilization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from sequence or structural similarity /// 0031931 // TORC1 complex // inferred from direct assay /// 0031931 // TORC1 complex // inferred from mutant phenotype /// 0031932 // TORC2 complex // inferred from direct assay /// 0070438 // mTOR-FKBP12-rapamycin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001030 // RNA polymerase III type 1 promoter DNA binding // inferred from direct assay /// 0001031 // RNA polymerase III type 2 promoter DNA binding // inferred from direct assay /// 0001032 // RNA polymerase III type 3 promoter DNA binding // inferred from direct assay /// 0001156 // TFIIIC-class transcription factor binding // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 202289_s_at NM_006997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006997.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 2 (TACC2), mRNA. /FEA=mRNA /GEN=TACC2 /PROD=transforming, acidic coiled-coil containingprotein 2 /DB_XREF=gi:11119413 /UG=Hs.272023 transforming, acidic coiled-coil containing protein 2 /FL=gb:AF095791.2 gb:NM_006997.1 NM_006997 transforming, acidic coiled-coil containing protein 2 TACC2 10579 NM_001291876 /// NM_001291877 /// NM_001291878 /// NM_001291879 /// NM_006997 /// NM_206860 /// NM_206861 /// NM_206862 /// XM_005269388 /// XM_005269389 /// XM_005269390 /// XM_005269391 /// XM_005269392 /// XM_005269393 /// XM_005269394 /// XM_005269395 /// XM_005269396 /// XM_005269397 /// XM_005269399 /// XM_006717548 /// XM_006717549 /// XM_006717550 /// XM_006717551 /// XM_006717552 /// XM_006717553 /// XM_006717554 /// XM_006717555 /// XM_006717556 /// XM_006717557 /// XM_006717558 /// XM_006717559 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030953 // astral microtubule organization // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay 202290_at NM_014891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014891.1 /DEF=Homo sapiens PDGF associated protein (HASPP28), mRNA. /FEA=mRNA /GEN=HASPP28 /PROD=PDGF associated protein /DB_XREF=gi:7657440 /UG=Hs.278426 PDGFA associated protein 1 /FL=gb:U41745.1 gb:BC000684.1 gb:NM_014891.1 NM_014891 PDGFA associated protein 1 PDAP1 11333 NM_014891 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 202291_s_at NM_000900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000900.1 /DEF=Homo sapiens matrix Gla protein (MGP), mRNA. /FEA=mRNA /GEN=MGP /PROD=matrix Gla protein /DB_XREF=gi:4505178 /UG=Hs.279009 matrix Gla protein /FL=gb:M58549.1 gb:NM_000900.1 NM_000900 matrix Gla protein MGP 4256 NM_000900 /// NM_001190839 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008147 // structural constituent of bone // traceable author statement 202292_x_at NM_007260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007260.1 /DEF=Homo sapiens lysophospholipase II (LYPLA2), mRNA. /FEA=mRNA /GEN=LYPLA2 /PROD=lysophospholipase II /DB_XREF=gi:9966763 /UG=Hs.283655 lysophospholipase II /FL=gb:AF098668.1 gb:NM_007260.1 NM_007260 lysophospholipase II LYPLA2 11313 NM_007260 /// XM_005245728 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 202293_at AW168948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW168948 /FEA=EST /DB_XREF=gi:6400473 /DB_XREF=est:xj15f07.x1 /CLONE=IMAGE:2657317 /UG=Hs.286148 stromal antigen 1 /FL=gb:NM_005862.1 AW168948 stromal antigen 1 STAG1 10274 NM_005862 /// XM_006713471 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202294_at AI126490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI126490 /FEA=EST /DB_XREF=gi:3595004 /DB_XREF=est:qd82h04.x1 /CLONE=IMAGE:1736023 /UG=Hs.286148 stromal antigen 1 /FL=gb:NM_005862.1 AI126490 stromal antigen 1 STAG1 10274 NM_005862 /// XM_006713471 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202295_s_at NM_004390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004390.1 /DEF=Homo sapiens cathepsin H (CTSH), mRNA. /FEA=mRNA /GEN=CTSH /PROD=cathepsin H /DB_XREF=gi:4758095 /UG=Hs.288181 cathepsin H /FL=gb:BC002479.1 gb:NM_004390.1 NM_004390 cathepsin H CTSH 1512 NM_004390 /// NM_148979 /// XM_005254181 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001913 // T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002764 // immune response-regulating signaling pathway // inferred from direct assay /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010813 // neuropeptide catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0019882 // antigen processing and presentation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031638 // zymogen activation // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043129 // surfactant homeostasis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0060448 // dichotomous subdivision of terminal units involved in lung branching // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0001520 // outer dense fiber // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004177 // aminopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030108 // HLA-A specific activating MHC class I receptor activity // inferred from direct assay /// 0030984 // kininogen binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay 202296_s_at NM_007033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007033.1 /DEF=Homo sapiens similar to S. cerevisiae RER1 (RER1), mRNA. /FEA=mRNA /GEN=RER1 /PROD=similar to S. cerevisiae RER1 /DB_XREF=gi:5902045 /UG=Hs.40500 similar to S. cerevisiae RER1 /FL=gb:BC004965.1 gb:NM_007033.1 gb:AF157324.1 NM_007033 retention in endoplasmic reticulum sorting receptor 1 RER1 11079 NM_007033 /// XM_005244713 /// XM_006710305 /// XM_006710306 /// XM_006710307 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 202297_s_at AF157324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF157324.1 /DEF=Homo sapiens RER1 protein (RER1) mRNA, complete cds. /FEA=mRNA /GEN=RER1 /PROD=RER1 protein /DB_XREF=gi:7688698 /UG=Hs.40500 similar to S. cerevisiae RER1 /FL=gb:BC004965.1 gb:NM_007033.1 gb:AF157324.1 AF157324 retention in endoplasmic reticulum sorting receptor 1 RER1 11079 NM_007033 /// XM_005244713 /// XM_006710305 /// XM_006710306 /// XM_006710307 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 202298_at NM_004541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004541.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) (NDUFA1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NDUFA1 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 1 /DB_XREF=gi:13699820 /UG=Hs.74823 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) /FL=gb:BC000266.1 gb:NM_004541.2 gb:U54993.1 NM_004541 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa NDUFA1 4694 NM_004541 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202299_s_at NM_006402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006402.1 /DEF=Homo sapiens hepatitis B virus x-interacting protein (9.6kD) (XIP), mRNA. /FEA=mRNA /GEN=XIP /PROD=hepatitis B virus x-interacting protein /DB_XREF=gi:5454169 /UG=Hs.80464 hepatitis B virus x-interacting protein (9.6kD) /FL=gb:AF029890.1 gb:NM_006402.1 NM_006402 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 LAMTOR5 10542 NM_006402 0008361 // regulation of cell size // inferred from mutant phenotype /// 0009615 // response to virus // traceable author statement /// 0019079 // viral genome replication // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0061462 // protein localization to lysosome // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 202300_at NM_006402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006402.1 /DEF=Homo sapiens hepatitis B virus x-interacting protein (9.6kD) (XIP), mRNA. /FEA=mRNA /GEN=XIP /PROD=hepatitis B virus x-interacting protein /DB_XREF=gi:5454169 /UG=Hs.80464 hepatitis B virus x-interacting protein (9.6kD) /FL=gb:AF029890.1 gb:NM_006402.1 NM_006402 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 LAMTOR5 10542 NM_006402 0008361 // regulation of cell size // inferred from mutant phenotype /// 0009615 // response to virus // traceable author statement /// 0019079 // viral genome replication // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0061462 // protein localization to lysosome // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 202301_s_at BE396879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE396879 /FEA=EST /DB_XREF=gi:9342244 /DB_XREF=est:601289401F1 /CLONE=IMAGE:3619848 /UG=Hs.81648 hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 /FL=gb:NM_023012.1 BE396879 arginine/serine-rich coiled-coil 2 RSRC2 65117 NM_023012 /// NM_198261 /// NM_198262 /// NR_036434 /// NR_036435 /// NR_036436 /// XM_005253601 /// XM_005253602 /// XM_005253604 /// XM_005253606 /// XR_242958 /// XR_242959 0044822 // poly(A) RNA binding // inferred from direct assay 202302_s_at NM_023012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023012.1 /DEF=Homo sapiens hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 (FLJ11021), mRNA. /FEA=mRNA /GEN=FLJ11021 /PROD=hypothetical protein FLJ11021 similar tosplicing factor, arginineserine-rich 4 /DB_XREF=gi:12711677 /UG=Hs.81648 hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 /FL=gb:NM_023012.1 NM_023012 arginine/serine-rich coiled-coil 2 RSRC2 65117 NM_023012 /// NM_198261 /// NM_198262 /// NR_036434 /// NR_036435 /// NR_036436 /// XM_005253601 /// XM_005253602 /// XM_005253604 /// XM_005253606 /// XR_242958 /// XR_242959 0044822 // poly(A) RNA binding // inferred from direct assay 202303_x_at NM_003601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003601.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (SMARCA5), mRNA. /FEA=mRNA /GEN=SMARCA5 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 /DB_XREF=gi:4507074 /UG=Hs.9456 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 /FL=gb:AB010882.1 gb:NM_003601.1 NM_003601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 SMARCA5 8467 NM_003601 0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005677 // chromatin silencing complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0031010 // ISWI-type complex // inferred from electronic annotation /// 0031213 // RSF complex // inferred from physical interaction /// 0043596 // nuclear replication fork // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay 202304_at NM_014923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014923.1 /DEF=Homo sapiens KIAA0970 protein (KIAA0970), mRNA. /FEA=mRNA /GEN=KIAA0970 /PROD=KIAA0970 protein /DB_XREF=gi:7662419 /UG=Hs.103329 KIAA0970 protein /FL=gb:AB023187.1 gb:NM_014923.1 NM_014923 fibronectin type III domain containing 3A FNDC3A 22862 NM_001079673 /// NM_001278438 /// NM_014923 /// NR_103528 /// XM_006719777 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202305_s_at AI685892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI685892 /FEA=EST /DB_XREF=gi:4897186 /DB_XREF=est:tu38a11.x1 /CLONE=IMAGE:2253308 /UG=Hs.103419 fasciculation and elongation protein zeta 2 (zygin II) /FL=gb:AF113124.1 gb:NM_005102.1 AI685892 fasciculation and elongation protein zeta 2 (zygin II) FEZ2 9637 NM_001042548 /// NM_005102 /// XM_006712153 /// XR_244972 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005515 // protein binding // inferred from physical interaction 202306_at NM_002696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002696.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide G (POLR2G), mRNA. /FEA=mRNA /GEN=POLR2G /PROD=polymerase (RNA) II (DNA directed) polypeptideG /DB_XREF=gi:4505946 /UG=Hs.14839 polymerase (RNA) II (DNA directed) polypeptide G /FL=gb:NM_002696.1 gb:U20659.1 NM_002696 polymerase (RNA) II (DNA directed) polypeptide G POLR2G 5436 NM_002696 0000291 // nuclear-transcribed mRNA catabolic process, exonucleolytic // not recorded /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045948 // positive regulation of translational initiation // not recorded /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // not recorded 0000932 // cytoplasmic mRNA processing body // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003697 // single-stranded DNA binding // not recorded /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // not recorded /// 0003899 // DNA-directed RNA polymerase activity // not recorded /// 0031369 // translation initiation factor binding // not recorded 202307_s_at NM_000593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000593.2 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 2 (ABCB2), mRNA. /FEA=mRNA /GEN=ABCB2 /PROD=ATP-binding cassette, sub-family B, member 2 /DB_XREF=gi:9665247 /UG=Hs.158164 ATP-binding cassette, sub-family B (MDRTAP), member 2 /FL=gb:L21204.1 gb:L21205.1 gb:L21206.1 gb:L21207.1 gb:L21208.1 gb:NM_000593.2 NM_000593 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) TAP1 6890 NM_000593 /// NM_001292022 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0046967 // cytosol to ER transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015197 // peptide transporter activity // inferred from genetic interaction /// 0015197 // peptide transporter activity // inferred from mutant phenotype /// 0015421 // oligopeptide-transporting ATPase activity // /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // non-traceable author statement /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043531 // ADP binding // inferred from direct assay /// 0046978 // TAP1 binding // inferred from sequence or structural similarity /// 0046979 // TAP2 binding // inferred from physical interaction /// 0046980 // tapasin binding // 202308_at NM_004176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004176.1 /DEF=Homo sapiens sterol regulatory element binding transcription factor 1 (SREBF1), mRNA. /FEA=mRNA /GEN=SREBF1 /PROD=sterol regulatory element binding transcriptionfactor 1 /DB_XREF=gi:4759167 /UG=Hs.166 sterol regulatory element binding transcription factor 1 /FL=gb:U00968.1 gb:NM_004176.1 NM_004176 sterol regulatory element binding transcription factor 1 SREBF1 6720 NM_001005291 /// NM_004176 /// XM_005256772 /// XM_006721570 /// XR_429821 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003062 // regulation of heart rate by chemical signal // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009749 // response to glucose // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032810 // sterol response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202309_at NM_005956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005956.2 /DEF=Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1), mRNA. /FEA=mRNA /GEN=MTHFD1 /PROD=methylenetetrahydrofolate dehydrogenase (NADP+dependent), methenyltetrahydrofolate cyclohydrolase,formyltetrahydrofolate synthetase /DB_XREF=gi:13699867 /UG=Hs.172665 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase /FL=gb:NM_005956.2 gb:J04031.1 NM_005956 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase MTHFD1 4522 NM_005956 0000105 // histidine biosynthetic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // not recorded /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // not recorded /// 0004329 // formate-tetrahydrofolate ligase activity // traceable author statement /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // traceable author statement /// 0004486 // methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity // traceable author statement /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202310_s_at K01228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K01228.1 /DEF=Human proalpha 1 (I) chain of type I procollagen mRNA (partial). /FEA=mRNA /GEN=COL1A1 /DB_XREF=gi:180391 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1 K01228 collagen, type I, alpha 1 COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202311_s_at AI743621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743621 /FEA=EST /DB_XREF=gi:5111909 /DB_XREF=est:wg51h09.x1 /CLONE=IMAGE:2368673 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1 AI743621 collagen, type I, alpha 1 COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202312_s_at NM_000088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000088.1 /DEF=Homo sapiens collagen, type I, alpha 1 (COL1A1), mRNA. /FEA=mRNA /GEN=COL1A1 /PROD=collagen, type I, alpha 1 /DB_XREF=gi:4502944 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1 NM_000088 collagen, type I, alpha 1 COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202313_at NM_002717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002717.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform (PPP2R2A), mRNA. /FEA=mRNA /GEN=PPP2R2A /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit B (PR 52), alpha isoform /DB_XREF=gi:4506018 /UG=Hs.179574 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform /FL=gb:M64929.1 gb:NM_002717.1 NM_002717 protein phosphatase 2, regulatory subunit B, alpha PPP2R2A 5520 NM_001177591 /// NM_002717 /// XM_005273559 /// XM_005273560 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043278 // response to morphine // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement 202314_at NM_000786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000786.1 /DEF=Homo sapiens cytochrome P450, 51 (lanosterol 14-alpha-demethylase) (CYP51), mRNA. /FEA=mRNA /GEN=CYP51 /PROD=cytochrome P450, 51 (lanosterol14-alpha-demethylase) /DB_XREF=gi:4503242 /UG=Hs.226213 cytochrome P450, 51 (lanosterol 14-alpha-demethylase) /FL=gb:U23942.1 gb:NM_000786.1 gb:D55653.1 NM_000786 cytochrome P450, family 51, subfamily A, polypeptide 1 /// leucine-rich repeats and death domain containing 1 CYP51A1 /// LRRD1 1595 /// 401387 NM_000786 /// NM_001045475 /// NM_001146152 /// NM_001161528 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033488 // cholesterol biosynthetic process via 24,25-dihydrolanosterol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070988 // demethylation // inferred from direct assay /// 0070988 // demethylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008398 // sterol 14-demethylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202315_s_at NM_004327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004327.2 /DEF=Homo sapiens breakpoint cluster region (BCR), transcript variant 1, mRNA. /FEA=mRNA /GEN=BCR /PROD=breakpoint cluster region, isoform 1 /DB_XREF=gi:11038638 /UG=Hs.234799 breakpoint cluster region /FL=gb:NM_004327.2 NM_004327 breakpoint cluster region BCR 613 NM_004327 /// NM_021574 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043314 // negative regulation of neutrophil degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 202316_x_at AW241715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW241715 /FEA=EST /DB_XREF=gi:6575469 /DB_XREF=est:xn74b08.x1 /CLONE=IMAGE:2700183 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) /FL=gb:AF043117.1 gb:NM_006048.1 AW241715 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202317_s_at NM_006048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006048.1 /DEF=Homo sapiens ubiquitination factor E4B (homologous to yeast UFD2) (UBE4B), mRNA. /FEA=mRNA /GEN=UBE4B /PROD=ubiquitination factor E4B (homologous to yeastUFD2) /DB_XREF=gi:5174482 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) /FL=gb:AF043117.1 gb:NM_006048.1 NM_006048 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202318_s_at AF306508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF306508.1 /DEF=Homo sapiens SUMO-1 specific protease FKSG6 mRNA, complete cds. /FEA=mRNA /PROD=SUMO-1 specific protease FKSG6 /DB_XREF=gi:11096243 /UG=Hs.27197 SUMO-1-specific protease /FL=gb:AF307849.1 gb:AF306508.1 gb:AF196304.1 gb:NM_015571.1 AF306508 SUMO1/sentrin specific peptidase 6 SENP6 26054 NM_001100409 /// NM_015571 /// XM_006715457 /// XR_241847 0006508 // proteolysis // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from mutant phenotype /// 0070646 // protein modification by small protein removal // inferred from direct assay /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from mutant phenotype 202319_at NM_015571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015571.1 /DEF=Homo sapiens SUMO-1-specific protease (KIAA0797), mRNA. /FEA=mRNA /GEN=KIAA0797 /PROD=SUMO-1-specific protease /DB_XREF=gi:7662311 /UG=Hs.27197 SUMO-1-specific protease /FL=gb:AF307849.1 gb:AF306508.1 gb:AF196304.1 gb:NM_015571.1 NM_015571 SUMO1/sentrin specific peptidase 6 SENP6 26054 NM_001100409 /// NM_015571 /// XM_006715457 /// XR_241847 0006508 // proteolysis // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from mutant phenotype /// 0070646 // protein modification by small protein removal // inferred from direct assay /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from mutant phenotype 202320_at NM_001520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001520.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ) (GTF3C1), mRNA. /FEA=mRNA /GEN=GTF3C1 /PROD=general transcription factor IIIC, polypeptide 1(alpha subunit, 220kD ) /DB_XREF=gi:4753160 /UG=Hs.331 general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ) /FL=gb:U02619.1 gb:NM_001520.1 NM_001520 general transcription factor IIIC, polypeptide 1, alpha 220kDa GTF3C1 2975 NM_001286242 /// NM_001520 /// XM_006721042 0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 202321_at AW299507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299507 /FEA=EST /DB_XREF=gi:6709184 /DB_XREF=est:xs40e12.x1 /CLONE=IMAGE:2772142 /UG=Hs.55498 geranylgeranyl diphosphate synthase 1 /FL=gb:AF057698.1 gb:BC005252.1 gb:AB017971.1 gb:AB016043.1 gb:AB019036.1 gb:NM_004837.1 gb:AF125394.1 AW299507 geranylgeranyl diphosphate synthase 1 GGPS1 9453 NM_001037277 /// NM_001037278 /// NM_004837 /// NR_036605 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0033386 // geranylgeranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from direct assay /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202322_s_at NM_004837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004837.1 /DEF=Homo sapiens geranylgeranyl diphosphate synthase 1 (GGPS1), mRNA. /FEA=mRNA /GEN=GGPS1 /PROD=geranylgeranyl diphosphate synthase 1 /DB_XREF=gi:4758429 /UG=Hs.55498 geranylgeranyl diphosphate synthase 1 /FL=gb:AF057698.1 gb:BC005252.1 gb:AB017971.1 gb:AB016043.1 gb:AB019036.1 gb:NM_004837.1 gb:AF125394.1 NM_004837 geranylgeranyl diphosphate synthase 1 GGPS1 9453 NM_001037277 /// NM_001037278 /// NM_004837 /// NR_036605 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0033386 // geranylgeranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from direct assay /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202323_s_at AI636775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI636775 /FEA=EST /DB_XREF=gi:4688105 /DB_XREF=est:ts89h01.x1 /CLONE=IMAGE:2238481 /UG=Hs.6831 golgi resident protein GCP60 /FL=gb:AB043587.1 gb:NM_022735.1 AI636775 acyl-CoA binding domain containing 3 ACBD3 64746 NM_022735 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202324_s_at NM_022735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022735.1 /DEF=Homo sapiens golgi resident protein GCP60 (GCP60), mRNA. /FEA=mRNA /GEN=GCP60 /PROD=golgi resident protein GCP60 /DB_XREF=gi:12232390 /UG=Hs.6831 golgi resident protein GCP60 /FL=gb:AB043587.1 gb:NM_022735.1 NM_022735 acyl-CoA binding domain containing 3 ACBD3 64746 NM_022735 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202325_s_at NM_001685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001685.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 (ATP5J), mRNA. /FEA=mRNA /GEN=ATP5J /PROD=ATP synthase, H+ transporting, mitochondrial /DB_XREF=gi:4502292 /UG=Hs.73851 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 /FL=gb:M37104.1 gb:M73031.1 gb:NM_001685.1 gb:AL110183.1 NM_001685 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 ATP5J 522 NM_001003696 /// NM_001003697 /// NM_001003701 /// NM_001003703 /// NM_001685 /// XM_005260992 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 202326_at NM_006709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006709.1 /DEF=Homo sapiens ankyrin repeat-containing protein (G9A), mRNA. /FEA=mRNA /GEN=G9A /PROD=ankyrin repeat-containing protein /DB_XREF=gi:5729833 /UG=Hs.75196 ankyrin repeat-containing protein /FL=gb:BC002686.1 gb:NM_006709.1 NM_006709 euchromatic histone-lysine N-methyltransferase 2 EHMT2 10919 NM_001289413 /// NM_006709 /// NM_025256 /// XM_005248824 /// XM_005272767 /// XM_005274833 /// XM_005274835 /// XM_005274913 /// XM_005275207 /// XM_005275209 /// XM_005275343 /// XM_005275345 /// XM_006714974 /// XM_006714975 /// XM_006714976 /// XM_006725028 /// XM_006725029 /// XM_006725467 /// XM_006725468 /// XM_006725469 /// XM_006725682 /// XM_006725683 /// XM_006725684 /// XM_006725892 /// XM_006725893 /// XM_006725981 /// XM_006725982 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from mutant phenotype /// 0018027 // peptidyl-lysine dimethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from sequence or structural similarity /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from sequence or structural similarity /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202327_s_at AA020938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA020938 /FEA=EST /DB_XREF=gi:1484673 /DB_XREF=est:ze64c09.s1 /CLONE=IMAGE:363760 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) /FL=gb:NM_000296.1 gb:U24497.1 gb:L33243.1 AA020938 polycystin-1-like /// polycystic kidney disease 1 (autosomal dominant) LOC101930075 /// PKD1 5310 /// 101930075 NM_000296 /// NM_001009944 /// XM_005255370 /// XM_005276493 /// XM_006720889 /// XM_006720890 /// XM_006720891 /// XM_006720892 /// XM_006720893 /// XM_006720894 /// XM_006720895 /// XR_429642 /// XR_429643 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // not recorded /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 202328_s_at NM_000296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000296.1 /DEF=Homo sapiens polycystic kidney disease 1 (autosomal dominant) (PKD1), mRNA. /FEA=mRNA /GEN=PKD1 /PROD=polycystic kidney disease 1 (autosomaldominant) /DB_XREF=gi:4505832 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) /FL=gb:NM_000296.1 gb:U24497.1 gb:L33243.1 NM_000296 polycystin-1-like /// polycystic kidney disease 1 (autosomal dominant) LOC101930075 /// PKD1 5310 /// 101930075 NM_000296 /// NM_001009944 /// XM_005255370 /// XM_005276493 /// XM_006720889 /// XM_006720890 /// XM_006720891 /// XM_006720892 /// XM_006720893 /// XM_006720894 /// XM_006720895 /// XR_429642 /// XR_429643 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // not recorded /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 202329_at NM_004383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004383.1 /DEF=Homo sapiens c-src tyrosine kinase (CSK), mRNA. /FEA=mRNA /GEN=CSK /PROD=c-src tyrosine kinase /DB_XREF=gi:4758077 /UG=Hs.77793 c-src tyrosine kinase /FL=gb:NM_004383.1 NM_004383 c-src tyrosine kinase CSK 1445 NM_001127190 /// NM_004383 /// XM_005254165 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010989 // negative regulation of low-density lipoprotein particle clearance // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0033673 // negative regulation of kinase activity // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from physical interaction /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from electronic annotation 202330_s_at NM_003362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003362.1 /DEF=Homo sapiens uracil-DNA glycosylase (UNG), mRNA. /FEA=mRNA /GEN=UNG /PROD=uracil-DNA glycosylase /DB_XREF=gi:6224978 /UG=Hs.78853 uracil-DNA glycosylase /FL=gb:NM_003362.1 NM_003362 uracil-DNA glycosylase UNG 7374 NM_003362 /// NM_080911 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from electronic annotation /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004844 // uracil DNA N-glycosylase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation 202331_at NM_000709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000709.1 /DEF=Homo sapiens branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) (BCKDHA), mRNA. /FEA=mRNA /GEN=BCKDHA /PROD=branched chain keto acid dehydrogenase E1, alphapolypeptide (maple syrup urine disease) /DB_XREF=gi:11386134 /UG=Hs.78950 branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) /FL=gb:NM_000709.1 NM_000709 branched chain keto acid dehydrogenase E1, alpha polypeptide BCKDHA 593 NM_000709 /// NM_001164783 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // inferred from direct assay /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from direct assay 0003826 // alpha-ketoacid dehydrogenase activity // inferred from direct assay /// 0003863 // 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202332_at NM_001894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001894.1 /DEF=Homo sapiens casein kinase 1, epsilon (CSNK1E), mRNA. /FEA=mRNA /GEN=CSNK1E /PROD=casein kinase 1, epsilon /DB_XREF=gi:4503092 /UG=Hs.79658 casein kinase 1, epsilon /FL=gb:NM_001894.1 gb:AB024597.1 gb:L37043.1 NM_001894 LOC400927-CSNK1E readthrough /// casein kinase 1, epsilon CSNK1E /// CSNK1E 1454 /// 102800317 NM_001289912 /// NM_001894 /// NM_152221 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202333_s_at AA877765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA877765 /FEA=EST /DB_XREF=gi:2986730 /DB_XREF=est:nr06f05.s1 /CLONE=IMAGE:1161057 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1 AA877765 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202334_s_at AI768723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768723 /FEA=EST /DB_XREF=gi:5235232 /DB_XREF=est:wh25c12.x1 /CLONE=IMAGE:2381782 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1 AI768723 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202335_s_at NM_003337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003337.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B), mRNA. /FEA=mRNA /GEN=UBE2B /PROD=ubiquitin-conjugating enzyme E2B (RAD6 homolog) /DB_XREF=gi:4507770 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1 NM_003337 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202336_s_at NM_000919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000919.1 /DEF=Homo sapiens peptidylglycine alpha-amidating monooxygenase (PAM), mRNA. /FEA=mRNA /GEN=PAM /PROD=peptidylglycine alpha-amidating monooxygenase /DB_XREF=gi:4505602 /UG=Hs.83920 peptidylglycine alpha-amidating monooxygenase /FL=gb:M37721.1 gb:NM_000919.1 NM_000919 peptidylglycine alpha-amidating monooxygenase PAM 5066 NM_000919 /// NM_001177306 /// NM_138766 /// NM_138821 /// NM_138822 /// NR_033440 /// XM_006714632 /// XM_006714633 /// XM_006714634 /// XM_006714635 /// XM_006714636 /// XM_006714637 /// XM_006714638 /// XM_006714639 /// XM_006714640 0001519 // peptide amidation // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006518 // peptide metabolic process // inferred from electronic annotation /// 0006518 // peptide metabolic process // non-traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from mutant phenotype /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0018032 // protein amidation // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // non-traceable author statement /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004504 // peptidylglycine monooxygenase activity // inferred from direct assay /// 0004598 // peptidylamidoglycolate lyase activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202337_at NM_007221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007221.1 /DEF=Homo sapiens polyamine-modulated factor 1 (PMF1), mRNA. /FEA=mRNA /GEN=PMF1 /PROD=polyamine-modulated factor 1 /DB_XREF=gi:6005831 /UG=Hs.94446 polyamine-modulated factor 1 /FL=gb:AF141310.1 gb:NM_007221.1 NM_007221 polyamine-modulated factor 1 PMF1 11243 NM_001199653 /// NM_001199654 /// NM_007221 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction 202338_at NM_003258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003258.1 /DEF=Homo sapiens thymidine kinase 1, soluble (TK1), mRNA. /FEA=mRNA /GEN=TK1 /PROD=thymidine kinase 1, soluble /DB_XREF=gi:4507518 /UG=Hs.105097 thymidine kinase 1, soluble /FL=gb:K02581.1 gb:NM_003258.1 NM_003258 thymidine kinase 1, soluble TK1 7083 NM_003258 /// XM_005257631 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014856 // skeletal muscle cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051414 // response to cortisol // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060138 // fetal process involved in parturition // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202339_at NM_004819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004819.1 /DEF=Homo sapiens symplekin; Huntingtin interacting protein I (SPK), mRNA. /FEA=mRNA /GEN=SPK /PROD=symplekin /DB_XREF=gi:4759195 /UG=Hs.107019 symplekin; Huntingtin interacting protein I /FL=gb:U49240.1 gb:NM_004819.1 NM_004819 symplekin SYMPK 8189 NM_004819 /// XM_005259286 /// XR_243962 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006398 // histone mRNA 3'-end processing // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202340_x_at NM_002135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002135.1 /DEF=Homo sapiens nuclear receptor subfamily 4, group A, member 1 (NR4A1), mRNA. /FEA=mRNA /GEN=NR4A1 /PROD=nuclear receptor subfamily 4, group A, member 1 /DB_XREF=gi:4504440 /UG=Hs.1119 nuclear receptor subfamily 4, group A, member 1 /FL=gb:L13740.1 gb:NM_002135.1 NM_002135 nuclear receptor subfamily 4, group A, member 1 NR4A1 3164 NM_001202233 /// NM_001202234 /// NM_002135 /// NM_173157 /// NM_173158 /// XM_005268822 /// XM_005268823 /// XM_005268824 /// XM_006719363 /// XM_006719364 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202341_s_at AA149745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA149745 /FEA=EST /DB_XREF=gi:1720818 /DB_XREF=est:zo02h04.s1 /CLONE=IMAGE:566551 /UG=Hs.12372 tripartite motif protein TRIM2 /FL=gb:AF220018.1 gb:NM_015271.1 AA149745 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202342_s_at NM_015271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015271.1 /DEF=Homo sapiens tripartite motif protein TRIM2 (KIAA0517), mRNA. /FEA=mRNA /GEN=KIAA0517 /PROD=tripartite motif protein TRIM2 /DB_XREF=gi:13446226 /UG=Hs.12372 tripartite motif protein TRIM2 /FL=gb:AF220018.1 gb:NM_015271.1 NM_015271 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202343_x_at NM_001862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001862.1 /DEF=Homo sapiens cytochrome c oxidase subunit Vb (COX5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX5B /PROD=cytochrome c oxidase subunit Vb /DB_XREF=gi:4502982 /UG=Hs.1342 cytochrome c oxidase subunit Vb /FL=gb:M19961.1 gb:NM_001862.1 NM_001862 cytochrome c oxidase subunit Vb COX5B 1329 NM_001862 0007585 // respiratory gaseous exchange // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202344_at NM_005526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005526.1 /DEF=Homo sapiens heat shock transcription factor 1 (HSF1), mRNA. /FEA=mRNA /GEN=HSF1 /PROD=heat shock transcription factor 1 /DB_XREF=gi:5031766 /UG=Hs.1499 heat shock transcription factor 1 /FL=gb:M64673.1 gb:NM_005526.1 NM_005526 heat shock transcription factor 1 HSF1 3297 NM_005526 /// XM_005272315 /// XM_005272316 /// XM_005272317 /// XR_246618 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0090231 // regulation of spindle checkpoint // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001162 // RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202345_s_at NM_001444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001444.1 /DEF=Homo sapiens fatty acid binding protein 5 (psoriasis-associated) (FABP5), mRNA. /FEA=mRNA /GEN=FABP5 /PROD=fatty acid binding protein 5(psoriasis-associated) /DB_XREF=gi:4557580 /UG=Hs.153179 fatty acid binding protein 5 (psoriasis-associated) /FL=gb:M94856.1 gb:NM_001444.1 NM_001444 fatty acid binding protein 5 (psoriasis-associated) FABP5 2171 NM_001444 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement 202346_at NM_005339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005339.2 /DEF=Homo sapiens huntingtin interacting protein 2 (HIP2), mRNA. /FEA=mRNA /GEN=HIP2 /PROD=huntingtin interacting protein 2 /DB_XREF=gi:12545382 /UG=Hs.155485 huntingtin interacting protein 2 /FL=gb:NM_005339.2 gb:U58522.1 gb:AB022435.1 NM_005339 ubiquitin-conjugating enzyme E2K UBE2K 3093 NM_001111112 /// NM_001111113 /// NM_005339 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 202347_s_at AB022435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB022435.1 /DEF=Homo sapiens LIG mRNA for E2 ubiquitin-conjugating enzyme, complete cds. /FEA=mRNA /GEN=LIG /PROD=E2 ubiquitin-conjugating enzyme /DB_XREF=gi:4996607 /UG=Hs.155485 huntingtin interacting protein 2 /FL=gb:NM_005339.2 gb:U58522.1 gb:AB022435.1 AB022435 ubiquitin-conjugating enzyme E2K UBE2K 3093 NM_001111112 /// NM_001111113 /// NM_005339 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 202348_s_at BC000674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000674.1 /DEF=Homo sapiens, dystonia 1, torsion (autosomal dominant; torsin A), clone MGC:1558, mRNA, complete cds. /FEA=mRNA /PROD=dystonia 1, torsion (autosomal dominant; torsinA) /DB_XREF=gi:12653776 /UG=Hs.19261 dystonia 1, torsion (autosomal dominant; torsin A) /FL=gb:BC000674.1 gb:AF007871.1 gb:NM_000113.1 BC000674 torsin family 1, member A (torsin A) TOR1A 1861 NM_000113 0000338 // protein deneddylation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0006996 // organelle organization // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0044319 // wound healing, spreading of cells // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0048489 // synaptic vesicle transport // inferred from mutant phenotype /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from sequence or structural similarity /// 0071763 // nuclear membrane organization // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 1900244 // positive regulation of synaptic vesicle endocytosis // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 202349_at NM_000113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000113.1 /DEF=Homo sapiens dystonia 1, torsion (autosomal dominant; torsin A) (DYT1), mRNA. /FEA=mRNA /GEN=DYT1 /PROD=torsin A /DB_XREF=gi:4557540 /UG=Hs.19261 dystonia 1, torsion (autosomal dominant; torsin A) /FL=gb:BC000674.1 gb:AF007871.1 gb:NM_000113.1 NM_000113 torsin family 1, member A (torsin A) TOR1A 1861 NM_000113 0000338 // protein deneddylation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0006996 // organelle organization // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0044319 // wound healing, spreading of cells // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0048489 // synaptic vesicle transport // inferred from mutant phenotype /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from sequence or structural similarity /// 0071763 // nuclear membrane organization // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 1900244 // positive regulation of synaptic vesicle endocytosis // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 202350_s_at NM_002380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002380.2 /DEF=Homo sapiens matrilin 2 (MATN2) precursor, transcript variant 1, mRNA. /FEA=mRNA /GEN=MATN2 /PROD=matrilin 2 precursor /DB_XREF=gi:13518036 /UG=Hs.19368 matrilin 2 /FL=gb:U69263.2 gb:NM_002380.2 NM_002380 uncharacterized LOC100506558 /// matrilin 2 LOC100506558 /// MATN2 4147 /// 100506558 NM_002380 /// NM_030583 /// XM_005250920 /// XR_108869 /// XR_133494 /// XR_171741 0001764 // neuron migration // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0031104 // dendrite regeneration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202351_at AI093579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI093579 /FEA=EST /DB_XREF=gi:3432555 /DB_XREF=est:qb15g06.x1 /CLONE=IMAGE:1696378 /UG=Hs.295726 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) /FL=gb:M14648.1 gb:NM_002210.1 AI093579 integrin, alpha V ITGAV 3685 NM_001144999 /// NM_001145000 /// NM_002210 /// XM_005246536 /// XM_006712513 0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0033690 // positive regulation of osteoblast proliferation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0046718 // viral entry into host cell // traceable author statement /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0052066 // entry of symbiont into host cell by promotion of host phagocytosis // non-traceable author statement /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 2000425 // regulation of apoptotic cell clearance // inferred from sequence or structural similarity /// 2000536 // negative regulation of entry of bacterium into host cell // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008305 // integrin complex // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035867 // alphav-beta3 integrin-IGF-1-IGF1R complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001846 // opsonin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031994 // insulin-like growth factor I binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity 202352_s_at AI446530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI446530 /FEA=EST /DB_XREF=gi:4295855 /DB_XREF=est:tj05b01.x1 /CLONE=IMAGE:2140585 /UG=Hs.4295 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 /FL=gb:AB003103.1 gb:NM_002816.1 AI446530 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 PSMD12 5718 NM_002816 /// NM_174871 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202353_s_at NM_002816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002816.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12), mRNA. /FEA=mRNA /GEN=PSMD12 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 12 /DB_XREF=gi:4506220 /UG=Hs.4295 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 /FL=gb:AB003103.1 gb:NM_002816.1 NM_002816 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 PSMD12 5718 NM_002816 /// NM_174871 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202354_s_at AW190445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190445 /FEA=EST /DB_XREF=gi:6464925 /DB_XREF=est:xl15c01.x1 /CLONE=IMAGE:2676288 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1 AW190445 general transcription factor IIF, polypeptide 1, 74kDa GTF2F1 2962 NM_002096 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202355_s_at BC000120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000120.1 /DEF=Homo sapiens, general transcription factor IIF, polypeptide 1 (74kD subunit), clone MGC:1732, mRNA, complete cds. /FEA=mRNA /PROD=general transcription factor IIF, polypeptide 1(74kD subunit) /DB_XREF=gi:12652738 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1 BC000120 general transcription factor IIF, polypeptide 1, 74kDa GTF2F1 2962 NM_002096 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202356_s_at NM_002096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002096.1 /DEF=Homo sapiens general transcription factor IIF, polypeptide 1 (74kD subunit) (GTF2F1), mRNA. /FEA=mRNA /GEN=GTF2F1 /PROD=general transcription factor IIF, polypeptide 1(74kD subunit) /DB_XREF=gi:4504196 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1 NM_002096 general transcription factor IIF, polypeptide 1, 74kDa GTF2F1 2962 NM_002096 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202357_s_at NM_001710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001710.1 /DEF=Homo sapiens B-factor, properdin (BF), mRNA. /FEA=mRNA /GEN=BF /PROD=B-factor, properdin /DB_XREF=gi:4502396 /UG=Hs.69771 B-factor, properdin /FL=gb:BC004143.1 gb:L15702.1 gb:NM_001710.1 gb:S67310.1 NM_001710 complement factor B CFB 629 NM_001710 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // non-traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202358_s_at BG434168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG434168 /FEA=EST /DB_XREF=gi:13340674 /DB_XREF=est:602506096F1 /CLONE=IMAGE:4603630 /UG=Hs.76906 KIAA0254 gene product /FL=gb:D87443.1 gb:NM_014758.1 BG434168 sorting nexin 19 SNX19 399979 NM_014758 /// XM_005271545 /// XM_005271546 /// XM_005271548 /// XM_005271549 /// XR_428976 /// XR_428977 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202359_s_at NM_014758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014758.1 /DEF=Homo sapiens KIAA0254 gene product (KIAA0254), mRNA. /FEA=mRNA /GEN=KIAA0254 /PROD=KIAA0254 gene product /DB_XREF=gi:7662025 /UG=Hs.76906 KIAA0254 gene product /FL=gb:D87443.1 gb:NM_014758.1 NM_014758 sorting nexin 19 SNX19 399979 NM_014758 /// XM_005271545 /// XM_005271546 /// XM_005271548 /// XM_005271549 /// XR_428976 /// XR_428977 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202360_at NM_014757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014757.2 /DEF=Homo sapiens mastermind (Drosophila), homolog of (MAML1), mRNA. /FEA=mRNA /GEN=MAML1 /PROD=homolog of Drosophila mastermind /DB_XREF=gi:13376996 /UG=Hs.76986 mastermind (Drosophila), homolog of /FL=gb:NM_014757.2 gb:D83785.1 NM_014757 mastermind-like 1 (Drosophila) MAML1 9794 NM_014757 0003162 // atrioventricular node development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from genetic interaction /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from electronic annotation /// 0060928 // atrioventricular node cell development // inferred from sequence or structural similarity 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction 202361_at NM_004922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004922.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member C (SEC24C), mRNA. /FEA=mRNA /GEN=SEC24C /PROD=SEC24 (S. cerevisiae) related gene family,member C /DB_XREF=gi:4758633 /UG=Hs.81964 SEC24 (S. cerevisiae) related gene family, member C /FL=gb:NM_004922.1 gb:D38555.1 NM_004922 SEC24 family member C SEC24C 9632 NM_004922 /// NM_198597 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 202362_at NM_002884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002884.1 /DEF=Homo sapiens RAP1A, member of RAS oncogene family (RAP1A), mRNA. /FEA=mRNA /GEN=RAP1A /PROD=RAP1A, member of RAS oncogene family /DB_XREF=gi:4506412 /UG=Hs.865 RAP1A, member of RAS oncogene family /FL=gb:NM_002884.1 gb:M22995.1 NM_002884 RAP1A, member of RAS oncogene family RAP1A 5906 NM_001010935 /// NM_001291896 /// NM_002884 /// XM_006710803 /// XR_246288 0000186 // activation of MAPKK activity // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay 202363_at AF231124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF231124.1 /DEF=Homo sapiens testican-1 mRNA, complete cds. /FEA=mRNA /PROD=testican-1 /DB_XREF=gi:7248844 /UG=Hs.93029 sparcosteonectin, cwcv and kazal-like domains proteoglycan (testican) /FL=gb:NM_004598.1 gb:AF231124.1 AF231124 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 SPOCK1 6695 NM_004598 0001558 // regulation of cell growth // non-traceable author statement /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0021953 // central nervous system neuron differentiation // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // non-traceable author statement /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay 202364_at NM_005962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005962.1 /DEF=Homo sapiens MAX-interacting protein 1 (MXI1), mRNA. /FEA=mRNA /GEN=MXI1 /PROD=MAX-interacting protein 1 /DB_XREF=gi:5174596 /UG=Hs.118630 MAX-interacting protein 1 /FL=gb:L07648.1 gb:NM_005962.1 gb:D63940.1 NM_005962 MAX interactor 1, dimerization protein MXI1 4601 NM_001008541 /// NM_005962 /// NM_130439 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 202365_at BC004815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004815.1 /DEF=Homo sapiens, clone MGC:5139, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5139) /DB_XREF=gi:13435956 /UG=Hs.127610 acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain /FL=gb:BC004815.1 gb:M26393.1 gb:NM_000017.1 BC004815 unc-119 homolog B (C. elegans) UNC119B 84747 NM_001080533 /// NM_032661 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from direct assay /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005929 // cilium // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 202366_at NM_000017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000017.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (ACADS), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADS /PROD=acyl-Coenzyme A dehydrogenase, C-2 to C-3 shortchain precursor /DB_XREF=gi:4557232 /UG=Hs.127610 acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain /FL=gb:BC004815.1 gb:M26393.1 gb:NM_000017.1 NM_000017 acyl-CoA dehydrogenase, C-2 to C-3 short chain ACADS 35 NM_000017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046359 // butyrate catabolic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004085 // butyryl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 202367_at NM_001913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001913.1 /DEF=Homo sapiens cut (Drosophila)-like 1 (CCAAT displacement protein) (CUTL1), mRNA. /FEA=mRNA /GEN=CUTL1 /PROD=cut (Drosophila)-like 1 (CCAAT displacementprotein) /DB_XREF=gi:4503168 /UG=Hs.147049 cut (Drosophila)-like 1 (CCAAT displacement protein) /FL=gb:NM_001913.1 gb:L12579.1 NM_001913 cut-like homeobox 1 CUX1 1523 NM_001202543 /// NM_001202544 /// NM_001202545 /// NM_001202546 /// NM_001913 /// NM_181500 /// NM_181552 /// XM_005250150 /// XM_005250151 /// XM_005250154 /// XM_006715854 /// XM_006715855 /// XM_006715856 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000301 // retrograde transport, vesicle recycling within Golgi // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 202368_s_at AI986461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI986461 /FEA=EST /DB_XREF=gi:5813738 /DB_XREF=est:wz65f07.x1 /CLONE=IMAGE:2562949 /UG=Hs.153954 TRAM-like protein /FL=gb:D31762.1 gb:NM_012288.1 AI986461 translocation associated membrane protein 2 TRAM2 9697 NM_012288 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202369_s_at NM_012288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012288.1 /DEF=Homo sapiens TRAM-like protein (KIAA0057), mRNA. /FEA=mRNA /GEN=KIAA0057 /PROD=TRAM-like protein /DB_XREF=gi:6912449 /UG=Hs.153954 TRAM-like protein /FL=gb:D31762.1 gb:NM_012288.1 NM_012288 translocation associated membrane protein 2 TRAM2 9697 NM_012288 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202370_s_at NM_001755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001755.1 /DEF=Homo sapiens core-binding factor, beta subunit (CBFB), transcript variant 2, mRNA. /FEA=mRNA /GEN=CBFB /PROD=core-binding factor, beta subunit, isoform 2 /DB_XREF=gi:13124872 /UG=Hs.179881 core-binding factor, beta subunit /FL=gb:NM_001755.1 NM_001755 core-binding factor, beta subunit CBFB 865 NM_001755 /// NM_022845 /// XM_005256212 /// XM_006721321 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202371_at NM_024863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024863.1 /DEF=Homo sapiens hypothetical protein FLJ21174 (FLJ21174), mRNA. /FEA=mRNA /GEN=FLJ21174 /PROD=hypothetical protein FLJ21174 /DB_XREF=gi:13376293 /UG=Hs.194329 hypothetical protein FLJ21174 /FL=gb:AF271783.1 gb:NM_024863.1 NM_024863 transcription elongation factor A (SII)-like 4 TCEAL4 79921 NM_001006935 /// NM_001006936 /// NM_001006937 /// NM_024863 /// XM_005262192 /// XM_005262193 /// XM_005262194 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation 202372_at BF240652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF240652 /FEA=EST /DB_XREF=gi:11154576 /DB_XREF=est:601875908F1 /CLONE=IMAGE:4099824 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1 BF240652 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006886 // intracellular protein transport // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202373_s_at AF255648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF255648.1 /DEF=Homo sapiens rGAP-iso mRNA, complete cds. /FEA=mRNA /PROD=rGAP-iso /DB_XREF=gi:12005820 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1 AF255648 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202374_s_at NM_012414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012414.1 /DEF=Homo sapiens rab3 GTPase-activating protein, non-catalytic subunit (150kD) (RAB3-GAP150), mRNA. /FEA=mRNA /GEN=RAB3-GAP150 /PROD=rab3 GTPase-activating protein, non-catalyticsubunit (150kD) /DB_XREF=gi:6912619 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1 NM_012414 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006886 // intracellular protein transport // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202375_at NM_014822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014822.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member D (SEC24D), mRNA. /FEA=mRNA /GEN=SEC24D /PROD=SEC24 (S. cerevisiae) related gene family,member D /DB_XREF=gi:7662658 /UG=Hs.19822 SEC24 (S. cerevisiae) related gene family, member D /FL=gb:AB018298.1 gb:AF130464.2 gb:NM_014822.1 NM_014822 SEC24 family member D SEC24D 9871 NM_014822 /// XM_005263378 /// XM_005263379 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 202376_at NM_001085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001085.2 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3), mRNA. /FEA=mRNA /GEN=SERPINA3 /PROD=alpha-1-antichymotrypsin, precursor /DB_XREF=gi:9665246 /UG=Hs.234726 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 /FL=gb:BC003559.1 gb:K01500.1 gb:NM_001085.2 NM_001085 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 SERPINA3 12 NM_001085 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0019216 // regulation of lipid metabolic process // non-traceable author statement /// 0030162 // regulation of proteolysis // not recorded /// 0030277 // maintenance of gastrointestinal epithelium // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202377_at AW026535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW026535 /FEA=EST /DB_XREF=gi:5880065 /DB_XREF=est:wv14f10.x1 /CLONE=IMAGE:2529547 /UG=Hs.23581 leptin receptor gene-related protein /FL=gb:NM_017526.1 AW026535 leptin receptor overlapping transcript LEPROT 54741 NM_001198681 /// NM_001198683 /// NM_017526 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 202378_s_at NM_017526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017526.1 /DEF=Homo sapiens leptin receptor gene-related protein (HSOBRGRP), mRNA. /FEA=mRNA /GEN=HSOBRGRP /PROD=leptin receptor gene-related protein /DB_XREF=gi:8923784 /UG=Hs.23581 leptin receptor gene-related protein /FL=gb:NM_017526.1 NM_017526 leptin receptor overlapping transcript LEPROT 54741 NM_001198681 /// NM_001198683 /// NM_017526 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 202379_s_at AI361805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI361805 /FEA=EST /DB_XREF=gi:4113426 /DB_XREF=est:qz24g07.x1 /CLONE=IMAGE:2027868 /UG=Hs.241493 natural killer-tumor recognition sequence /FL=gb:L04288.2 gb:NM_005385.2 AI361805 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202380_s_at NM_005385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005385.2 /DEF=Homo sapiens natural killer-tumor recognition sequence (NKTR), mRNA. /FEA=mRNA /GEN=NKTR /PROD=natural killer-tumor recognition sequence /DB_XREF=gi:6631099 /UG=Hs.241493 natural killer-tumor recognition sequence /FL=gb:L04288.2 gb:NM_005385.2 NM_005385 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202381_at NM_003816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003816.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 9 (meltrin gamma) (ADAM9), mRNA. /FEA=mRNA /GEN=ADAM9 /PROD=a disintegrin and metalloproteinase domain 9preproprotein /DB_XREF=gi:4501914 /UG=Hs.2442 a disintegrin and metalloproteinase domain 9 (meltrin gamma) /FL=gb:U41766.1 gb:NM_003816.1 NM_003816 ADAM metallopeptidase domain 9 ADAM9 8754 NM_001005845 /// NM_003816 /// NR_027638 /// NR_027639 /// NR_027878 0000186 // activation of MAPKK activity // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred by curator /// 0010042 // response to manganese ion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030574 // collagen catabolic process // traceable author statement /// 0033627 // cell adhesion mediated by integrin // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034241 // positive regulation of macrophage fusion // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from direct assay /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // traceable author statement /// 0051384 // response to glucocorticoid // inferred from sequence or structural similarity /// 0051549 // positive regulation of keratinocyte migration // inferred from mutant phenotype /// 0051592 // response to calcium ion // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031233 // intrinsic component of external side of plasma membrane // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005178 // integrin binding // inferred by curator /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202382_s_at NM_005471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005471.1 /DEF=Homo sapiens glucosamine-6-phosphate isomerase (GNPI), mRNA. /FEA=mRNA /GEN=GNPI /PROD=glucosamine-6-phosphate isomerase /DB_XREF=gi:13027377 /UG=Hs.278500 glucosamine-6-phosphate isomerase /FL=gb:NM_005471.1 gb:AF029914.1 gb:AF048826.1 gb:D31766.1 NM_005471 glucosamine-6-phosphate deaminase 1 GNPDA1 10007 NM_005471 /// XM_005268348 /// XM_006714747 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006043 // glucosamine catabolic process // inferred from mutant phenotype /// 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0007338 // single fertilization // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004342 // glucosamine-6-phosphate deaminase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 202383_at NM_004187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004187.1 /DEF=Homo sapiens SMC (mouse) homolog, X chromosome (SMCX), mRNA. /FEA=mRNA /GEN=SMCX /PROD=SMC (mouse) homolog, X chromosome /DB_XREF=gi:11321604 /UG=Hs.283429 SMC (mouse) homolog, X chromosome /FL=gb:NM_004187.1 gb:L25270.1 NM_004187 lysine (K)-specific demethylase 5C KDM5C 8242 NM_001146702 /// NM_001282622 /// NM_004187 /// XM_005262035 /// XM_006724609 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 202384_s_at AW167713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW167713 /FEA=EST /DB_XREF=gi:6399238 /DB_XREF=est:xn48b02.x1 /CLONE=IMAGE:2696907 /UG=Hs.301266 Treacher Collins-Franceschetti syndrome 1 /FL=gb:U76366.1 gb:U40847.1 gb:NM_000356.1 AW167713 Treacher Collins-Franceschetti syndrome 1 TCOF1 6949 NM_000356 /// NM_001008656 /// NM_001008657 /// NM_001135243 /// NM_001135244 /// NM_001135245 /// NM_001195141 /// XM_005268502 /// XM_005268503 /// XM_005268504 /// XM_005268505 /// XM_005268506 /// XM_005268507 /// XM_005268508 /// XM_005268509 /// XR_427778 /// XR_427779 /// XR_427780 0001501 // skeletal system development // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0042790 // transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202385_s_at NM_000356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000356.1 /DEF=Homo sapiens Treacher Collins-Franceschetti syndrome 1 (TCOF1), mRNA. /FEA=mRNA /GEN=TCOF1 /PROD=treacle /DB_XREF=gi:4507410 /UG=Hs.301266 Treacher Collins-Franceschetti syndrome 1 /FL=gb:U76366.1 gb:U40847.1 gb:NM_000356.1 NM_000356 Treacher Collins-Franceschetti syndrome 1 TCOF1 6949 NM_000356 /// NM_001008656 /// NM_001008657 /// NM_001135243 /// NM_001135244 /// NM_001135245 /// NM_001195141 /// XM_005268502 /// XM_005268503 /// XM_005268504 /// XM_005268505 /// XM_005268506 /// XM_005268507 /// XM_005268508 /// XM_005268509 /// XR_427778 /// XR_427779 /// XR_427780 0001501 // skeletal system development // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0042790 // transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202386_s_at NM_019081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019081.1 /DEF=Homo sapiens KIAA0430 gene product (KIAA0430), mRNA. /FEA=mRNA /GEN=KIAA0430 /PROD=hypothetical protein A-362G6.1 /DB_XREF=gi:11464998 /UG=Hs.30909 KIAA0430 gene product /FL=gb:NM_019081.1 NM_019081 KIAA0430 KIAA0430 9665 NM_001184998 /// NM_001184999 /// NM_014647 /// NM_019081 /// XM_005255704 /// XM_005255705 /// XM_005255706 /// XM_005255707 /// XM_005255708 /// XM_005255709 /// XM_006720986 /// XM_006725215 /// XM_006725216 /// XM_006725217 /// XM_006725218 /// XM_006725219 /// XM_006725220 /// XM_006725221 0006302 // double-strand break repair // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 202387_at NM_004323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004323.2 /DEF=Homo sapiens BCL2-associated athanogene (BAG1), mRNA. /FEA=mRNA /GEN=BAG1 /PROD=BCL2-associated athanogene /DB_XREF=gi:7549801 /UG=Hs.41714 BCL2-associated athanogene /FL=gb:BC001936.1 gb:AF022224.1 gb:U46917.1 gb:NM_004323.2 NM_004323 BCL2-associated athanogene BAG1 573 NM_001172415 /// NM_004323 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202388_at NM_002923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002923.1 /DEF=Homo sapiens regulator of G-protein signalling 2, 24kD (RGS2), mRNA. /FEA=mRNA /GEN=RGS2 /PROD=regulator of G-protein signalling 2, 24kD /DB_XREF=gi:4506516 /UG=Hs.78944 regulator of G-protein signalling 2, 24kD /FL=gb:L13463.1 gb:NM_002923.1 NM_002923 regulator of G-protein signaling 2 RGS2 5997 NM_002923 0006417 // regulation of translation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010519 // negative regulation of phospholipase activity // inferred from sequence or structural similarity /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055119 // relaxation of cardiac muscle // inferred from sequence or structural similarity /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0071877 // regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement /// 0048487 // beta-tubulin binding // inferred from electronic annotation 202389_s_at L12392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12392.1 /DEF=Homo sapiens Huntingtons Disease (HD) mRNA, complete cds. /FEA=mRNA /GEN=HD /PROD=Huntingtons Disease protein /DB_XREF=gi:1709991 /UG=Hs.79391 huntingtin (Huntington disease) /FL=gb:L12392.1 gb:L20431.1 gb:NM_002111.3 L12392 huntingtin HTT 3064 NM_002111 0000050 // urea cycle // inferred from electronic annotation /// 0000052 // citrulline metabolic process // inferred from electronic annotation /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0019244 // lactate biosynthetic process from pyruvate // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0021990 // neural plate formation // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048513 // organ development // not recorded /// 0048666 // neuron development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016234 // inclusion body // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0034452 // dynactin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0045505 // dynein intermediate chain binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050809 // diazepam binding // inferred from electronic annotation 202390_s_at NM_002111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002111.3 /DEF=Homo sapiens huntingtin (Huntington disease) (HD), mRNA. /FEA=mRNA /GEN=HD /PROD=huntingtin /DB_XREF=gi:4755137 /UG=Hs.79391 huntingtin (Huntington disease) /FL=gb:L12392.1 gb:L20431.1 gb:NM_002111.3 NM_002111 huntingtin HTT 3064 NM_002111 0000050 // urea cycle // inferred from electronic annotation /// 0000052 // citrulline metabolic process // inferred from electronic annotation /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0019244 // lactate biosynthetic process from pyruvate // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0021990 // neural plate formation // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048513 // organ development // not recorded /// 0048666 // neuron development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016234 // inclusion body // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0034452 // dynactin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0045505 // dynein intermediate chain binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050809 // diazepam binding // inferred from electronic annotation 202391_at NM_006317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006317.1 /DEF=Homo sapiens brain acid-soluble protein 1 (BASP1), mRNA. /FEA=mRNA /GEN=BASP1 /PROD=brain acid-soluble protein 1 /DB_XREF=gi:5453749 /UG=Hs.79516 brain abundant, membrane attached signal protein 1 /FL=gb:BC000518.1 gb:AF039656.1 gb:NM_006317.1 NM_006317 brain abundant, membrane attached signal protein 1 BASP1 10409 NM_001271606 /// NM_006317 0007356 // thorax and anterior abdomen determination // inferred from sequence or structural similarity /// 0008406 // gonad development // inferred from sequence or structural similarity /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0060421 // positive regulation of heart growth // inferred from sequence or structural similarity /// 0060539 // diaphragm development // inferred from sequence or structural similarity /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 2001076 // positive regulation of metanephric ureteric bud development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 202392_s_at NM_014338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014338.1 /DEF=Homo sapiens phosphatidylserine decarboxylase (PISD), mRNA. /FEA=mRNA /GEN=PISD /PROD=phosphatidylserine decarboxylase /DB_XREF=gi:13489111 /UG=Hs.8128 phosphatidylserine decarboxylase /FL=gb:NM_014338.1 NM_014338 microRNA 7109 /// phosphatidylserine decarboxylase MIR7109 /// PISD 23761 /// 102465666 NM_014338 /// NR_106959 /// XM_005261455 /// XM_005261456 /// XM_005261457 /// XM_005261458 /// XM_005261459 /// XM_005261460 /// XM_005261461 /// XM_005261462 /// XM_006724199 /// XM_006724200 /// XM_006724201 /// XM_006724202 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0004609 // phosphatidylserine decarboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 202393_s_at NM_005655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005655.1 /DEF=Homo sapiens TGFB inducible early growth response (TIEG), mRNA. /FEA=mRNA /GEN=TIEG /PROD=TGFB inducible early growth response /DB_XREF=gi:5032176 /UG=Hs.82173 TGFB inducible early growth response /FL=gb:U21847.1 gb:NM_005655.1 NM_005655 Kruppel-like factor 10 KLF10 7071 NM_001032282 /// NM_005655 /// NR_103759 /// NR_103760 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202394_s_at NM_018358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018358.1 /DEF=Homo sapiens hypothetical protein FLJ11198 (FLJ11198), mRNA. /FEA=mRNA /GEN=FLJ11198 /PROD=hypothetical protein FLJ11198 /DB_XREF=gi:8922935 /UG=Hs.91251 hypothetical protein FLJ11198 /FL=gb:NM_018358.1 NM_018358 ATP-binding cassette, sub-family F (GCN20), member 3 ABCF3 55324 NM_018358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 202395_at NM_006178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006178.1 /DEF=Homo sapiens N-ethylmaleimide-sensitive factor (NSF), mRNA. /FEA=mRNA /GEN=NSF /PROD=N-ethylmaleimide-sensitive factor /DB_XREF=gi:11079227 /UG=Hs.108802 N-ethylmaleimide-sensitive factor /FL=gb:AF102846.2 gb:NM_006178.1 gb:AF135168.1 NM_006178 uncharacterized LOC101930324 /// N-ethylmaleimide-sensitive factor LOC101930324 /// NSF 4905 /// 101930324 NM_006178 /// NR_040116 /// XM_006721929 /// XM_006725276 /// XM_006725626 /// XR_250612 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045026 // plasma membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from sequence or structural similarity /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202396_at NM_006706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006706.1 /DEF=Homo sapiens transcription factor CA150 (CA150), mRNA. /FEA=mRNA /GEN=CA150 /PROD=transcription factor CA150 /DB_XREF=gi:5729753 /UG=Hs.13063 transcription factor CA150 /FL=gb:AF017789.1 gb:NM_006706.1 NM_006706 transcription elongation regulator 1 TCERG1 10915 NM_001040006 /// NM_006706 /// XM_005268365 /// XM_005268366 /// XM_005268367 /// XM_006714754 /// XR_245850 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 202397_at NM_005796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005796.1 /DEF=Homo sapiens nuclear transport factor 2 (placental protein 15) (PP15), mRNA. /FEA=mRNA /GEN=PP15 /PROD=nuclear transport factor 2 (placental protein15) /DB_XREF=gi:5031984 /UG=Hs.151734 nuclear transport factor 2 (placental protein 15) /FL=gb:U43939.1 gb:BC002348.1 gb:NM_005796.1 NM_005796 nuclear transport factor 2 /// nuclear transport factor 2 pseudogene 4 NUTF2 /// NUTF2P4 10204 /// 128322 NM_005796 /// XM_003960108 /// XM_005255771 /// XM_060943 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202398_at BC002785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002785.1 /DEF=Homo sapiens, adaptor-related protein complex 3, sigma 2 subunit, clone MGC:3577, mRNA, complete cds. /FEA=mRNA /PROD=adaptor-related protein complex 3, sigma 2subunit /DB_XREF=gi:12803880 /UG=Hs.154782 adaptor-related protein complex 3, sigma 2 subunit /FL=gb:BC002785.1 gb:NM_005829.1 BC002785 adaptor-related protein complex 3, sigma 2 subunit /// C15orf38-AP3S2 readthrough AP3S2 /// C15orf38-AP3S2 10239 /// 100526783 NM_001199058 /// NM_005829 /// NR_023361 /// NR_037582 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 202399_s_at NM_005829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005829.1 /DEF=Homo sapiens adaptor-related protein complex 3, sigma 2 subunit (AP3S2), mRNA. /FEA=mRNA /GEN=AP3S2 /PROD=adaptor-related protein complex 3, sigma 2subunit /DB_XREF=gi:5031580 /UG=Hs.154782 adaptor-related protein complex 3, sigma 2 subunit /FL=gb:BC002785.1 gb:NM_005829.1 NM_005829 adaptor-related protein complex 3, sigma 2 subunit /// C15orf38-AP3S2 readthrough AP3S2 /// C15orf38-AP3S2 10239 /// 100526783 NM_001199058 /// NM_005829 /// NR_023361 /// NR_037582 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 202400_s_at AI188786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI188786 /FEA=EST /DB_XREF=gi:3739995 /DB_XREF=est:qd16g09.x1 /CLONE=IMAGE:1723936 /UG=Hs.155321 serum response factor (c-fos serum response element-binding transcription factor) /FL=gb:J03161.1 gb:NM_003131.1 AI188786 serum response factor (c-fos serum response element-binding transcription factor) SRF 6722 NM_001292001 /// NM_003131 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from direct assay /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0009725 // response to hormone // inferred from direct assay /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030038 // contractile actin filament bundle assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from mutant phenotype /// 0034097 // response to cytokine // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from direct assay /// 0046016 // positive regulation of transcription by glucose // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048666 // neuron development // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051150 // regulation of smooth muscle cell differentiation // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060947 // cardiac vascular smooth muscle cell differentiation // inferred from electronic annotation /// 0061029 // eyelid development in camera-type eye // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900222 // negative regulation of beta-amyloid clearance // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0010736 // serum response element binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202401_s_at NM_003131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003131.1 /DEF=Homo sapiens serum response factor (c-fos serum response element-binding transcription factor) (SRF), mRNA. /FEA=mRNA /GEN=SRF /PROD=serum response factor (c-fos serum responseelement-binding transcription factor) /DB_XREF=gi:4507204 /UG=Hs.155321 serum response factor (c-fos serum response element-binding transcription factor) /FL=gb:J03161.1 gb:NM_003131.1 NM_003131 serum response factor (c-fos serum response element-binding transcription factor) SRF 6722 NM_001292001 /// NM_003131 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from direct assay /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0009725 // response to hormone // inferred from direct assay /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030038 // contractile actin filament bundle assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from mutant phenotype /// 0034097 // response to cytokine // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from direct assay /// 0046016 // positive regulation of transcription by glucose // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048666 // neuron development // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051150 // regulation of smooth muscle cell differentiation // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060947 // cardiac vascular smooth muscle cell differentiation // inferred from electronic annotation /// 0061029 // eyelid development in camera-type eye // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900222 // negative regulation of beta-amyloid clearance // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0010736 // serum response element binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202402_s_at NM_001751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001751.1 /DEF=Homo sapiens cysteinyl-tRNA synthetase (CARS), mRNA. /FEA=mRNA /GEN=CARS /PROD=cysteinyl-tRNA synthetase /DB_XREF=gi:10835050 /UG=Hs.159604 cysteinyl-tRNA synthetase /FL=gb:NM_001751.1 gb:BC002880.1 gb:AF288206.1 gb:AF288207.1 NM_001751 cysteinyl-tRNA synthetase CARS 833 NM_001014437 /// NM_001014438 /// NM_001194997 /// NM_001751 /// NM_139273 /// NR_036542 /// XM_006718340 /// XM_006718341 /// XM_006725129 /// XM_006725130 /// XR_428857 /// XR_430701 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006423 // cysteinyl-tRNA aminoacylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000049 // tRNA binding // inferred from mutant phenotype /// 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004817 // cysteine-tRNA ligase activity // inferred from direct assay /// 0004817 // cysteine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202403_s_at AA788711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA788711 /FEA=EST /DB_XREF=gi:2848831 /DB_XREF=est:ag40g07.s1 /CLONE=IMAGE:1119324 /UG=Hs.179573 collagen, type I, alpha 2 /FL=gb:J03464.1 gb:NM_000089.1 AA788711 collagen, type I, alpha 2 COL1A2 1278 NM_000089 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0042476 // odontogenesis // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from direct assay /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005584 // collagen type I trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202404_s_at NM_000089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000089.1 /DEF=Homo sapiens collagen, type I, alpha 2 (COL1A2), mRNA. /FEA=mRNA /GEN=COL1A2 /PROD=collagen, type I, alpha 2 /DB_XREF=gi:4502946 /UG=Hs.179573 collagen, type I, alpha 2 /FL=gb:J03464.1 gb:NM_000089.1 NM_000089 collagen, type I, alpha 2 COL1A2 1278 NM_000089 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0042476 // odontogenesis // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from direct assay /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005584 // collagen type I trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202405_at BF432532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432532 /FEA=EST /DB_XREF=gi:11444682 /DB_XREF=est:nac56b07.x1 /CLONE=IMAGE:3406405 /UG=Hs.182741 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 /FL=gb:NM_003252.2 gb:M96954.1 BF432532 TIA1 cytotoxic granule-associated RNA binding protein-like 1 TIAL1 7073 NM_001033925 /// NM_003252 /// XM_005270108 /// XM_005270109 /// XM_005270110 /// XM_006717959 /// XR_428715 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202406_s_at NM_003252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003252.2 /DEF=Homo sapiens TIA1 cytotoxic granule-associated RNA-binding protein-like 1 (TIAL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TIAL1 /PROD=TIA1 cytotoxic granule-associated RNA-bindingprotein-like 1, isoform 1 /DB_XREF=gi:13435392 /UG=Hs.182741 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 /FL=gb:NM_003252.2 gb:M96954.1 NM_003252 TIA1 cytotoxic granule-associated RNA binding protein-like 1 TIAL1 7073 NM_001033925 /// NM_003252 /// XM_005270108 /// XM_005270109 /// XM_005270110 /// XM_006717959 /// XR_428715 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202407_s_at BF342707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF342707 /FEA=EST /DB_XREF=gi:11289729 /DB_XREF=est:602013660F1 /CLONE=IMAGE:4149542 /UG=Hs.183438 DKFZP566J153 protein /FL=gb:AL050369.1 gb:NM_015629.1 BF342707 pre-mRNA processing factor 31 PRPF31 26121 NM_015629 /// XM_005258729 /// XM_005277071 /// XM_005277249 /// XM_005278258 /// XM_006723137 /// XM_006725641 /// XM_006725767 /// XM_006725768 /// XM_006725868 /// XM_006725869 /// XM_006725956 /// XM_006725957 /// XM_006726055 /// XM_006726056 /// XM_006726153 /// XM_006726154 /// XM_006726193 /// XM_006726194 /// XM_006726273 /// XM_006726309 0000244 // spliceosomal tri-snRNP complex assembly // inferred from direct assay /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005684 // U2-type spliceosomal complex // inferred by curator /// 0005687 // U4 snRNP // inferred from direct assay /// 0005690 // U4atac snRNP // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070990 // snRNP binding // inferred from physical interaction 202408_s_at NM_015629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015629.1 /DEF=Homo sapiens DKFZP566J153 protein (DKFZP566J153), mRNA. /FEA=mRNA /GEN=DKFZP566J153 /PROD=DKFZP566J153 protein /DB_XREF=gi:7661653 /UG=Hs.183438 DKFZP566J153 protein /FL=gb:AL050369.1 gb:NM_015629.1 NM_015629 pre-mRNA processing factor 31 PRPF31 26121 NM_015629 /// XM_005258729 /// XM_005277071 /// XM_005277249 /// XM_005278258 /// XM_006723137 /// XM_006725641 /// XM_006725767 /// XM_006725768 /// XM_006725868 /// XM_006725869 /// XM_006725956 /// XM_006725957 /// XM_006726055 /// XM_006726056 /// XM_006726153 /// XM_006726154 /// XM_006726193 /// XM_006726194 /// XM_006726273 /// XM_006726309 0000244 // spliceosomal tri-snRNP complex assembly // inferred from direct assay /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005684 // U2-type spliceosomal complex // inferred by curator /// 0005687 // U4 snRNP // inferred from direct assay /// 0005690 // U4atac snRNP // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070990 // snRNP binding // inferred from physical interaction 202409_at X07868 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07868 /DEF=Human DNA for insulin-like growth factor II (IGF-2); exon 7 and additional ORF /FEA=mRNA_1 /DB_XREF=gi:32998 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:BC000531.1 gb:J03242.1 gb:M17426.1 gb:NM_000612.2 X07868 insulin-like growth factor 2 (somatomedin A) /// INS-IGF2 readthrough IGF2 /// INS-IGF2 3481 /// 723961 NM_000612 /// NM_001007139 /// NM_001042376 /// NM_001127598 /// NM_001291861 /// NM_001291862 /// NR_003512 0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 202410_x_at NM_000612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000612.2 /DEF=Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), mRNA. /FEA=mRNA /GEN=IGF2 /PROD=insulin-like growth factor 2 (somatomedin A) /DB_XREF=gi:6453816 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:BC000531.1 gb:J03242.1 gb:M17426.1 gb:NM_000612.2 NM_000612 insulin-like growth factor 2 (somatomedin A) /// INS-IGF2 readthrough IGF2 /// INS-IGF2 3481 /// 723961 NM_000612 /// NM_001007139 /// NM_001042376 /// NM_001127598 /// NM_001291861 /// NM_001291862 /// NR_003512 0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 202411_at NM_005532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005532.1 /DEF=Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNA. /FEA=mRNA /GEN=IFI27 /PROD=interferon, alpha-inducible protein 27 /DB_XREF=gi:5031780 /UG=Hs.278613 interferon, alpha-inducible protein 27 /FL=gb:NM_005532.1 NM_005532 interferon, alpha-inducible protein 27 IFI27 3429 NM_001130080 /// NM_001288952 /// NM_001288954 /// NM_001288956 /// NM_001288957 /// NM_001288958 /// NM_001288959 /// NM_001288960 /// NM_001288995 /// NM_005532 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202412_s_at AW499935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW499935 /FEA=EST /DB_XREF=gi:7112073 /DB_XREF=est:UI-HF-BN0-akf-f-02-0-UI.r1 /CLONE=IMAGE:3077114 /UG=Hs.35086 ubiquitin specific protease 1 /FL=gb:AB014458.1 gb:AF117386.1 gb:NM_003368.1 gb:AL117575.1 AW499935 ubiquitin specific peptidase 1 USP1 7398 NM_001017415 /// NM_001017416 /// NM_003368 0006281 // DNA repair // traceable author statement /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202413_s_at NM_003368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003368.1 /DEF=Homo sapiens ubiquitin specific protease 1 (USP1), mRNA. /FEA=mRNA /GEN=USP1 /PROD=ubiquitin specific protease 1 /DB_XREF=gi:4507850 /UG=Hs.35086 ubiquitin specific protease 1 /FL=gb:AB014458.1 gb:AF117386.1 gb:NM_003368.1 gb:AL117575.1 NM_003368 ubiquitin specific peptidase 1 USP1 7398 NM_001017415 /// NM_001017416 /// NM_003368 0006281 // DNA repair // traceable author statement /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202414_at NM_000123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000123.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (ERCC5), mRNA. /FEA=mRNA /GEN=ERCC5 /PROD=XPG-complementing protein /DB_XREF=gi:4503600 /UG=Hs.48576 excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) /FL=gb:D16305.1 gb:L20046.1 gb:NM_000123.1 NM_000123 excision repair cross-complementation group 5 ERCC5 2073 NM_000123 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from direct assay /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0009650 // UV protection // inferred from genetic interaction /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000405 // bubble DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004520 // endodeoxyribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 202415_s_at NM_012267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012267.1 /DEF=Homo sapiens hsp70-interacting protein (HSPBP1), mRNA. /FEA=mRNA /GEN=HSPBP1 /PROD=hsp70-interacting protein /DB_XREF=gi:6912423 /UG=Hs.53066 hsp70-interacting protein /FL=gb:AB020592.1 gb:AF093420.1 gb:NM_012267.1 gb:AF187859.1 NM_012267 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 HSPBP1 23640 NM_001130106 /// NM_012267 /// XM_005258700 /// XM_005258701 /// XM_005258703 0006457 // protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement 0004857 // enzyme inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202416_at NM_003315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003315.1 /DEF=Homo sapiens tetratricopeptide repeat domain 2 (TTC2), mRNA. /FEA=mRNA /GEN=TTC2 /PROD=tetratricopeptide repeat domain 2 /DB_XREF=gi:4507712 /UG=Hs.5542 DnaJ (Hsp40) homolog, subfamily C, member 7 /FL=gb:U46571.1 gb:NM_003315.1 NM_003315 DnaJ (Hsp40) homolog, subfamily C, member 7 DNAJC7 7266 NM_001144766 /// NM_003315 /// NR_029431 /// XM_006722050 /// XM_006722051 /// XM_006722052 /// XM_006722053 /// XM_006722054 0006457 // protein folding // traceable author statement /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction 202417_at NM_012289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012289.1 /DEF=Homo sapiens Kelch-like ECH-associated protein 1 (KIAA0132), mRNA. /FEA=mRNA /GEN=KIAA0132 /PROD=Kelch-like ECH-associated protein 1 /DB_XREF=gi:6912451 /UG=Hs.57729 Kelch-like ECH-associated protein 1 /FL=gb:BC002417.1 gb:BC002930.1 gb:D50922.1 gb:NM_012289.1 NM_012289 kelch-like ECH-associated protein 1 KEAP1 9817 NM_012289 /// NM_203500 /// XM_005260173 /// XM_005260174 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045604 // regulation of epidermal cell differentiation // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202418_at NM_020470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020470.1 /DEF=Homo sapiens putative transmembrane protein; homolog of yeast Golgi membrane protein Yif1p (Yip1p-interacting factor) (54TM), mRNA. /FEA=mRNA /GEN=54TM /PROD=putative transmembrane protein; homolog of yeastGolgi membrane protein Yif1p (Yip1p-interacting factor) /DB_XREF=gi:9994168 /UG=Hs.5809 putative transmembrane protein; homolog of yeast Golgi membrane protein Yif1p (Yip1p-interacting factor) /FL=gb:BC001299.1 gb:AF004876.1 gb:NM_020470.1 NM_020470 Yip1 interacting factor homolog A (S. cerevisiae) YIF1A 10897 NM_020470 /// XM_005273720 /// XM_005273721 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202419_at NM_002035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002035.1 /DEF=Homo sapiens follicular lymphoma variant translocation 1 (FVT1), mRNA. /FEA=mRNA /GEN=FVT1 /PROD=follicular lymphoma variant translocation 1 /DB_XREF=gi:4503816 /UG=Hs.74050 follicular lymphoma variant translocation 1 /FL=gb:NM_002035.1 NM_002035 3-ketodihydrosphingosine reductase KDSR 2531 NM_002035 /// XM_005266677 /// XM_006722433 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006666 // 3-keto-sphinganine metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047560 // 3-dehydrosphinganine reductase activity // inferred from direct assay 202420_s_at NM_001357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001357.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) (DDX9), transcript variant 1, mRNA. /FEA=mRNA /GEN=DDX9 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9,isoform 1 /DB_XREF=gi:13514819 /UG=Hs.74578 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) /FL=gb:NM_001357.2 gb:L13848.1 NM_001357 DEAH (Asp-Glu-Ala-His) box helicase 9 DHX9 1660 NM_001357 /// NM_030588 /// NR_033302 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202421_at AB007935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007935.1 /DEF=Homo sapiens mRNA for KIAA0466 protein, partial cds. /FEA=mRNA /GEN=KIAA0466 /PROD=KIAA0466 protein /DB_XREF=gi:3413893 /UG=Hs.81234 immunoglobulin superfamily, member 3 /FL=gb:AF031174.1 gb:NM_001542.1 AB007935 immunoglobulin superfamily, member 3 IGSF3 3321 NM_001007237 /// NM_001542 /// XM_005270793 /// XM_005270794 /// XM_006710593 0032808 // lacrimal gland development // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 202422_s_at NM_022977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022977.1 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 4 (FACL4), transcript variant 2, mRNA. /FEA=mRNA /GEN=FACL4 /PROD=long-chain fatty-acid-Coenzyme A ligase 4,isoform 2 /DB_XREF=gi:12669908 /UG=Hs.81452 fatty-acid-Coenzyme A ligase, long-chain 4 /FL=gb:NM_022977.1 NM_022977 acyl-CoA synthetase long-chain family member 4 ACSL4 2182 NM_004458 /// NM_022977 /// XM_005262108 /// XM_005262109 /// XM_005262110 /// XM_006724635 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0032307 // negative regulation of prostaglandin secretion // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from electronic annotation /// 0070672 // response to interleukin-15 // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0047676 // arachidonate-CoA ligase activity // inferred from direct assay 202423_at NM_006766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006766.1 /DEF=Homo sapiens zinc finger protein 220 (ZNF220), mRNA. /FEA=mRNA /GEN=ZNF220 /PROD=zinc finger protein 220 /DB_XREF=gi:5803097 /UG=Hs.82210 zinc finger protein 220 /FL=gb:U47742.1 gb:NM_006766.1 NM_006766 K(lysine) acetyltransferase 6A KAT6A 7994 NM_001099412 /// NM_001099413 /// NM_006766 /// XM_005273649 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202424_at NM_030662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030662.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 2 (MAP2K2), mRNA. /FEA=mRNA /GEN=MAP2K2 /PROD=mitogen-activated protein kinase kinase 2 /DB_XREF=gi:13489053 /UG=Hs.72241 mitogen-activated protein kinase kinase 2 /FL=gb:BC000471.1 gb:NM_030662.1 NM_030662 mitogen-activated protein kinase kinase 2 MAP2K2 5605 NM_030662 /// XM_006722799 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036289 // peptidyl-serine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000147 // positive regulation of cell motility // inferred from electronic annotation /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 202425_x_at NM_000944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000944.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) (PPP3CA), mRNA. /FEA=mRNA /GEN=PPP3CA /PROD=protein phosphatase 3 (formerly 2B), catalyticsubunit, alpha isoform (calcineurin A alpha) /DB_XREF=gi:6715567 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1 NM_000944 protein phosphatase 3, catalytic subunit, alpha isozyme PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202426_s_at BE675800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675800 /FEA=EST /DB_XREF=gi:10036341 /DB_XREF=est:7f16c05.x1 /CLONE=IMAGE:3294824 /UG=Hs.20084 retinoid X receptor, alpha /FL=gb:NM_002957.2 BE675800 retinoid X receptor, alpha RXRA 6256 NM_001291920 /// NM_001291921 /// NM_002957 /// XM_005263409 /// XM_006717232 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070644 // vitamin D response element binding // inferred from direct assay 202427_s_at NM_015415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015415.1 /DEF=Homo sapiens DKFZP564B167 protein (DKFZP564B167), mRNA. /FEA=mRNA /GEN=DKFZP564B167 /PROD=DKFZP564B167 protein /DB_XREF=gi:7661601 /UG=Hs.76285 DKFZP564B167 protein /FL=gb:AL110297.1 gb:NM_015415.1 NM_015415 mitochondrial pyruvate carrier 2 MPC2 25874 NM_001143674 /// NM_015415 /// NR_026550 /// XM_006711266 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006850 // mitochondrial pyruvate transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901475 // pyruvate transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0050833 // pyruvate transmembrane transporter activity // inferred from electronic annotation 202428_x_at NM_020548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020548.1 /DEF=Homo sapiens diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (DBI), mRNA. /FEA=mRNA /GEN=DBI /PROD=diazepam binding inhibitor /DB_XREF=gi:10140852 /UG=Hs.78888 diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) /FL=gb:NM_020548.1 gb:M14200.1 NM_020548 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) DBI 1622 NM_001079862 /// NM_001079863 /// NM_001178017 /// NM_001178041 /// NM_001178042 /// NM_001178043 /// NM_001282633 /// NM_001282634 /// NM_001282635 /// NM_001282636 /// NM_020548 /// NR_104221 0001942 // hair follicle development // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030156 // benzodiazepine receptor binding // traceable author statement /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 202429_s_at AL353950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL353950.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L0516 (from clone DKFZp761L0516); complete cds. /FEA=mRNA /GEN=DKFZp761L0516 /PROD=hypothetical protein /DB_XREF=gi:7669991 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1 AL353950 protein phosphatase 3, catalytic subunit, alpha isozyme PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202430_s_at NM_021105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021105.1 /DEF=Homo sapiens phospholipid scramblase 1 (PLSCR1), mRNA. /FEA=mRNA /GEN=PLSCR1 /PROD=phospholipid scramblase 1 /DB_XREF=gi:10863876 /UG=Hs.198282 phospholipid scramblase 1 /FL=gb:NM_021105.1 gb:AB006746.1 gb:AF098642.1 NM_021105 phospholipid scramblase 1 PLSCR1 5359 NM_021105 /// XM_005247538 0006659 // phosphatidylserine biosynthetic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0017121 // phospholipid scrambling // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 2000373 // positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from direct assay /// 0017128 // phospholipid scramblase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042609 // CD4 receptor binding // inferred from physical interaction 202431_s_at NM_002467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002467.1 /DEF=Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC), mRNA. /FEA=mRNA /GEN=MYC /PROD=v-myc avian myelocytomatosis viral oncogenehomolog /DB_XREF=gi:12962934 /UG=Hs.79070 v-myc avian myelocytomatosis viral oncogene homolog /FL=gb:BC000141.1 gb:BC000917.2 gb:NM_002467.1 NM_002467 v-myc avian myelocytomatosis viral oncogene homolog MYC 4609 NM_002467 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006879 // cellular iron ion homeostasis // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0032204 // regulation of telomere maintenance // inferred from mutant phenotype /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from expression pattern /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044346 // fibroblast apoptotic process // traceable author statement /// 0045656 // negative regulation of monocyte differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051276 // chromosome organization // inferred from direct assay /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0070848 // response to growth factor // traceable author statement /// 0090096 // positive regulation of metanephric cap mesenchymal cell proliferation // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0044195 // nucleoplasmic reticulum // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay /// 0071074 // eukaryotic initiation factor eIF2 binding // inferred from physical interaction 202432_at NM_021132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021132.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) (PPP3CB), mRNA. /FEA=mRNA /GEN=PPP3CB /PROD=protein phosphatase 3 (formerly 2B), catalyticsubunit, beta isoform (calcineurin A beta) /DB_XREF=gi:11036639 /UG=Hs.151531 protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) /FL=gb:NM_021132.1 gb:M29551.1 NM_021132 protein phosphatase 3, catalytic subunit, beta isozyme PPP3CB 5532 NM_001142353 /// NM_001142354 /// NM_001289968 /// NM_001289969 /// NM_021132 /// XM_005269944 /// XM_005269945 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007612 // learning // traceable author statement /// 0007613 // memory // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035176 // social behavior // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0048675 // axon extension // traceable author statement /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005955 // calcineurin complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from sequence or structural similarity /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202433_at NM_005827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005827.1 /DEF=Homo sapiens UDP-galactose transporter related (UGTREL1), mRNA. /FEA=mRNA /GEN=UGTREL1 /PROD=UDP-galactose transporter related /DB_XREF=gi:5032212 /UG=Hs.154073 UDP-galactose transporter related /FL=gb:D87989.1 gb:NM_005827.1 NM_005827 solute carrier family 35, member B1 SLC35B1 10237 NM_001278784 /// NM_005827 /// XM_005256929 /// XM_006721632 0006810 // transport // traceable author statement /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0072334 // UDP-galactose transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0005459 // UDP-galactose transmembrane transporter activity // traceable author statement 202434_s_at N21019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21019 /FEA=EST /DB_XREF=gi:1126189 /DB_XREF=est:yx46b08.s1 /CLONE=IMAGE:264759 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1 N21019 cytochrome P450, family 1, subfamily B, polypeptide 1 CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 202435_s_at AU154504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154504 /FEA=EST /DB_XREF=gi:11016025 /DB_XREF=est:AU154504 /CLONE=NT2RP4001328 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1 AU154504 cytochrome P450, family 1, subfamily B, polypeptide 1 CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 202436_s_at AU144855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144855 /FEA=EST /DB_XREF=gi:11006376 /DB_XREF=est:AU144855 /CLONE=HEMBA1003161 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1 AU144855 cytochrome P450, family 1, subfamily B, polypeptide 1 CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 202437_s_at NM_000104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000104.2 /DEF=Homo sapiens cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) (CYP1B1), mRNA. /FEA=mRNA /GEN=CYP1B1 /PROD=cytochrome P450, subfamily I (dioxin-inducible),polypeptide 1 /DB_XREF=gi:13325059 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1 NM_000104 cytochrome P450, family 1, subfamily B, polypeptide 1 CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 202438_x_at BF346014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF346014 /FEA=EST /DB_XREF=gi:11293609 /DB_XREF=est:602018737F1 /CLONE=IMAGE:4154216 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:M58342.1 gb:NM_000202.2 BF346014 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202439_s_at NM_000202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000202.2 /DEF=Homo sapiens iduronate 2-sulfatase (Hunter syndrome) (IDS), transcript variant 1, mRNA. /FEA=mRNA /GEN=IDS /PROD=iduronate-2-sulfatase isoform a precursor /DB_XREF=gi:5360215 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:M58342.1 gb:NM_000202.2 NM_000202 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202440_s_at NM_005418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005418.1 /DEF=Homo sapiens suppression of tumorigenicity 5 (ST5), mRNA. /FEA=mRNA /GEN=ST5 /PROD=suppression of tumorigenicity 5 /DB_XREF=gi:4885612 /UG=Hs.79265 suppression of tumorigenicity 5 /FL=gb:U15131.1 gb:U15779.1 gb:NM_005418.1 NM_005418 suppression of tumorigenicity 5 ST5 6764 NM_005418 /// NM_139157 /// NM_213618 /// XM_005253077 /// XM_005253079 /// XM_005253080 /// XM_005253081 /// XM_005253083 /// XM_005253084 /// XM_006718284 /// XM_006718285 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 202441_at AL568449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568449 /FEA=EST /DB_XREF=gi:12922799 /DB_XREF=est:AL568449 /CLONE=CS0DE001YC12 (3 prime) /UG=Hs.285818 similar to Caenorhabditis elegans protein C42C1.9 /FL=gb:AF064093.1 gb:NM_006459.1 AL568449 ER lipid raft associated 1 ERLIN1 10613 NM_001100626 /// NM_006459 /// XM_005269442 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202442_at NM_001284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001284.1 /DEF=Homo sapiens adaptor-related protein complex 3, sigma 1 subunit (AP3S1), mRNA. /FEA=mRNA /GEN=AP3S1 /PROD=adaptor-related protein complex 3, sigma 1subunit /DB_XREF=gi:4502860 /UG=Hs.80917 adaptor-related protein complex 3, sigma 1 subunit /FL=gb:BC000804.1 gb:D63643.1 gb:U91932.1 gb:NM_001284.1 NM_001284 adaptor-related protein complex 3, sigma 1 subunit AP3S1 1176 NM_001002924 /// NM_001284 /// XM_005271872 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030133 // transport vesicle // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 202443_x_at AA291203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA291203 /FEA=EST /DB_XREF=gi:1939386 /DB_XREF=est:zt38h02.s1 /CLONE=IMAGE:724659 /UG=Hs.8121 Notch (Drosophila) homolog 2 /FL=gb:AF315356.1 gb:NM_024408.1 AA291203 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 202444_s_at NM_006459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006459.1 /DEF=Homo sapiens similar to Caenorhabditis elegans protein C42C1.9 (KEO4), mRNA. /FEA=mRNA /GEN=KEO4 /PROD=similar to Caenorhabditis elegans proteinC42C1.9 /DB_XREF=gi:5453705 /UG=Hs.285818 similar to Caenorhabditis elegans protein C42C1.9 /FL=gb:AF064093.1 gb:NM_006459.1 NM_006459 ER lipid raft associated 1 ERLIN1 10613 NM_001100626 /// NM_006459 /// XM_005269442 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202445_s_at NM_024408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024408.1 /DEF=Homo sapiens Notch (Drosophila) homolog 2 (NOTCH2), mRNA. /FEA=mRNA /GEN=NOTCH2 /PROD=Notch (Drosophila) homolog 2 /DB_XREF=gi:13249343 /UG=Hs.8121 Notch (Drosophila) homolog 2 /FL=gb:AF315356.1 gb:NM_024408.1 NM_024408 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 202446_s_at AI825926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825926 /FEA=EST /DB_XREF=gi:5446597 /DB_XREF=est:to92d05.x1 /CLONE=IMAGE:2185737 /UG=Hs.198282 phospholipid scramblase 1 /FL=gb:NM_021105.1 gb:AB006746.1 gb:AF098642.1 AI825926 phospholipid scramblase 1 PLSCR1 5359 NM_021105 /// XM_005247538 0006659 // phosphatidylserine biosynthetic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0017121 // phospholipid scrambling // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 2000373 // positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from direct assay /// 0017128 // phospholipid scramblase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042609 // CD4 receptor binding // inferred from physical interaction 202447_at NM_001359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001359.1 /DEF=Homo sapiens 2,4-dienoyl CoA reductase 1, mitochondrial (DECR1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=DECR1 /PROD=2,4-dienoyl CoA reductase 1 precursor /DB_XREF=gi:4503300 /UG=Hs.81548 2,4-dienoyl CoA reductase 1, mitochondrial /FL=gb:U49352.1 gb:NM_001359.1 gb:L26050.1 NM_001359 2,4-dienoyl CoA reductase 1, mitochondrial DECR1 1666 NM_001359 /// XM_005250808 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008670 // 2,4-dienoyl-CoA reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay 202448_s_at BE675849 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675849 /FEA=EST /DB_XREF=gi:10036390 /DB_XREF=est:7f17c03.x1 /CLONE=IMAGE:3294916 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1 BE675849 zyg-11 related, cell cycle regulator ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202449_s_at NM_002957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002957.2 /DEF=Homo sapiens retinoid X receptor, alpha (RXRA), mRNA. /FEA=mRNA /GEN=RXRA /PROD=retinoid X receptor, alpha /DB_XREF=gi:10862707 /UG=Hs.20084 retinoid X receptor, alpha /FL=gb:NM_002957.2 NM_002957 retinoid X receptor, alpha RXRA 6256 NM_001291920 /// NM_001291921 /// NM_002957 /// XM_005263409 /// XM_006717232 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070644 // vitamin D response element binding // inferred from direct assay 202450_s_at NM_000396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000396.1 /DEF=Homo sapiens cathepsin K (pycnodysostosis) (CTSK), mRNA. /FEA=mRNA /GEN=CTSK /PROD=cathepsin K (pycnodysostosis) /DB_XREF=gi:4503150 /UG=Hs.83942 cathepsin K (pycnodysostosis) /FL=gb:NM_000396.1 gb:U13665.1 NM_000396 cathepsin K CTSK 1513 NM_000396 0001957 // intramembranous ossification // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045453 // bone resorption // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 202451_at BC000365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000365.1 /DEF=Homo sapiens, general transcription factor IIH, polypeptide 1 (62kD subunit), clone MGC:8323, mRNA, complete cds. /FEA=mRNA /PROD=general transcription factor IIH, polypeptide 1(62kD subunit) /DB_XREF=gi:12653194 /UG=Hs.89578 general transcription factor IIH, polypeptide 1 (62kD subunit) /FL=gb:BC000365.1 gb:BC004452.1 gb:M95809.1 gb:NM_005316.1 BC000365 general transcription factor IIH, polypeptide 1, 62kDa GTF2H1 2965 NM_001142307 /// NM_005316 /// XM_006718208 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay 202452_at AI991574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991574 /FEA=EST /DB_XREF=gi:5838479 /DB_XREF=est:ws17h05.x1 /CLONE=IMAGE:2497497 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1 AI991574 zyg-11 related, cell cycle regulator ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202453_s_at NM_005316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005316.1 /DEF=Homo sapiens general transcription factor IIH, polypeptide 1 (62kD subunit) (GTF2H1), mRNA. /FEA=mRNA /GEN=GTF2H1 /PROD=general transcription factor IIH, polypeptide 1(62kD subunit) /DB_XREF=gi:4885364 /UG=Hs.89578 general transcription factor IIH, polypeptide 1 (62kD subunit) /FL=gb:BC000365.1 gb:BC004452.1 gb:M95809.1 gb:NM_005316.1 NM_005316 general transcription factor IIH, polypeptide 1, 62kDa GTF2H1 2965 NM_001142307 /// NM_005316 /// XM_006718208 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay 202454_s_at NM_001982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001982.1 /DEF=Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3), mRNA. /FEA=mRNA /GEN=ERBB3 /PROD=v-erb-b2 avian erythroblastic leukemia viraloncogene homolog 3 /DB_XREF=gi:4503596 /UG=Hs.199067 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 /FL=gb:M29366.1 gb:M34309.1 gb:NM_001982.1 NM_001982 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 ERBB3 2065 NM_001005915 /// NM_001982 0003197 // endocardial cushion development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043235 // receptor complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from sequence or structural similarity /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 202455_at NM_005474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005474.2 /DEF=Homo sapiens histone deacetylase 5 (HDAC5), mRNA. /FEA=mRNA /GEN=HDAC5 /PROD=histone deacetylase 5 /DB_XREF=gi:13259520 /UG=Hs.9028 histone deacetylase 5 /FL=gb:NM_005474.2 gb:AF132608.1 NM_005474 histone deacetylase 5 HDAC5 10014 NM_001015053 /// NM_005474 /// NM_139205 /// XM_005256904 /// XM_005256905 /// XM_005256906 /// XM_005256907 /// XM_006721629 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006342 // chromatin silencing // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from direct assay /// 0030183 // B cell differentiation // traceable author statement /// 0032869 // cellular response to insulin stimulus // non-traceable author statement /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0042113 // B cell activation // traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048742 // regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051153 // regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from mutant phenotype 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 202456_s_at NM_006336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006336.1 /DEF=Homo sapiens ZYG homolog (ZYG), mRNA. /FEA=mRNA /GEN=ZYG /PROD=ZYG homolog /DB_XREF=gi:5454185 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1 NM_006336 zyg-11 related, cell cycle regulator ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202457_s_at AA911231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA911231 /FEA=EST /DB_XREF=gi:3050521 /DB_XREF=est:ol49c10.s1 /CLONE=IMAGE:1526802 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1 AA911231 protein phosphatase 3, catalytic subunit, alpha isozyme PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202458_at NM_007173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007173.1 /DEF=Homo sapiens protease, serine, 23 (SPUVE), mRNA. /FEA=mRNA /GEN=SPUVE /PROD=protease, serine, 23 /DB_XREF=gi:6005881 /UG=Hs.325820 protease, serine, 23 /FL=gb:AL136914.1 gb:BC001278.1 gb:AF015287.1 gb:NM_007173.1 gb:AF193611.1 NM_007173 protease, serine, 23 PRSS23 11098 NM_001293178 /// NM_001293179 /// NM_001293180 /// NM_007173 /// NR_120591 /// NR_120592 /// NR_120593 /// XM_005273727 /// XR_424260 /// XR_428964 /// XR_432738 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202459_s_at U55968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U55968 /FEA=EST /DB_XREF=gi:1354524 /DB_XREF=est:HSU55968 /CLONE=26508 /UG=Hs.166318 lipin 2 /FL=gb:D87436.1 gb:NM_014646.1 U55968 lipin 2 LPIN2 9663 NM_014646 /// XM_005258177 /// XM_005258178 /// XM_005258179 /// XM_006722368 /// XR_243814 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0008195 // phosphatidate phosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 202460_s_at NM_014646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014646.1 /DEF=Homo sapiens lipin 2 (LPIN2), mRNA. /FEA=mRNA /GEN=LPIN2 /PROD=lipin 2 /DB_XREF=gi:7662021 /UG=Hs.166318 lipin 2 /FL=gb:D87436.1 gb:NM_014646.1 NM_014646 lipin 2 LPIN2 9663 NM_014646 /// XM_005258177 /// XM_005258178 /// XM_005258179 /// XM_006722368 /// XR_243814 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0008195 // phosphatidate phosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 202461_at NM_014239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014239.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD) (EIF2B2), mRNA. /FEA=mRNA /GEN=EIF2B2 /PROD=eukaryotic translation initiation factor 2B,subunit 2 (beta, 39kD) /DB_XREF=gi:7657057 /UG=Hs.170001 eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD) /FL=gb:BC000494.1 gb:BC003165.1 gb:AF035280.1 gb:NM_014239.1 NM_014239 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa EIF2B2 8892 NM_014239 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // not recorded /// 0006446 // regulation of translational initiation // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0042552 // myelination // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 202462_s_at NM_014829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014829.1 /DEF=Homo sapiens KIAA0801 gene product (KIAA0801), mRNA. /FEA=mRNA /GEN=KIAA0801 /PROD=KIAA0801 gene product /DB_XREF=gi:7662317 /UG=Hs.17585 KIAA0801 gene product /FL=gb:AB018344.1 gb:NM_014829.1 NM_014829 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 DDX46 9879 NM_014829 /// XM_005272142 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202463_s_at NM_003926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003926.4 /DEF=Homo sapiens methyl-CpG binding domain protein 3 (MBD3), mRNA. /FEA=mRNA /GEN=MBD3 /PROD=methyl-CpG binding domain protein 3 /DB_XREF=gi:7710147 /UG=Hs.178728 methyl-CpG binding domain protein 3 /FL=gb:BC000872.1 gb:NM_003926.4 NM_003926 methyl-CpG binding domain protein 3 MBD3 53615 NM_001281453 /// NM_001281454 /// NM_003926 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016581 // NuRD complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay 202464_s_at NM_004566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004566.1 /DEF=Homo sapiens 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 (PFKFB3), mRNA. /FEA=mRNA /GEN=PFKFB3 /PROD=6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 /DB_XREF=gi:4758899 /UG=Hs.195471 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 /FL=gb:D49817.1 gb:AF109735.1 gb:NM_004566.1 NM_004566 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 PFKFB3 5209 NM_001145443 /// NM_001282630 /// NM_004566 /// XM_005252463 /// XM_005252464 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // non-traceable author statement /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202465_at NM_002593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002593.2 /DEF=Homo sapiens procollagen C-endopeptidase enhancer (PCOLCE), mRNA. /FEA=mRNA /GEN=PCOLCE /PROD=procollagen C-endopeptidase enhancer /DB_XREF=gi:7262388 /UG=Hs.202097 procollagen C-endopeptidase enhancer /FL=gb:BC000574.1 gb:AB008549.1 gb:L33799.1 gb:NM_002593.2 NM_002593 procollagen C-endopeptidase enhancer PCOLCE 5118 NM_002593 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016504 // peptidase activator activity // inferred from direct assay 202466_at NM_006999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006999.2 /DEF=Homo sapiens topoisomerase-related function protein 4-1 (TRF4), mRNA. /FEA=mRNA /GEN=TRF4 /PROD=topoisomerase-related function protein 4-1 /DB_XREF=gi:6631114 /UG=Hs.225951 topoisomerase-related function protein 4-1 /FL=gb:AB005754.3 gb:NM_006999.2 NM_006999 PAP associated domain containing 7 PAPD7 11044 NM_001171805 /// NM_001171806 /// NM_006999 /// XM_005248234 /// XM_005248236 /// XM_006714438 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006302 // double-strand break repair // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0043221 // SMC family protein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202467_s_at NM_004236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004236.1 /DEF=Homo sapiens thyroid receptor interacting protein 15 (TRIP15), mRNA. /FEA=mRNA /GEN=TRIP15 /PROD=thyroid receptor interacting protein 15 /DB_XREF=gi:4759263 /UG=Hs.30212 thyroid receptor interacting protein 15 /FL=gb:AF084260.1 gb:NM_004236.1 gb:AF120268.1 gb:AF100762.1 NM_004236 COP9 signalosome subunit 2 COPS2 9318 NM_001143887 /// NM_004236 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010388 // cullin deneddylation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202468_s_at NM_003798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003798.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha-like 1 (CTNNAL1), mRNA. /FEA=mRNA /GEN=CTNNAL1 /PROD=catenin (cadherin-associated protein),alpha-like 1 /DB_XREF=gi:4503128 /UG=Hs.58488 catenin (cadherin-associated protein), alpha-like 1 /FL=gb:AF006070.1 gb:U97067.1 gb:AF080071.1 gb:AF030233.1 gb:NM_003798.1 NM_003798 catenin (cadherin-associated protein), alpha-like 1 CTNNAL1 8727 NM_001286974 /// NM_003798 /// XM_005252291 0007155 // cell adhesion // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 202469_s_at AU149367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149367 /FEA=EST /DB_XREF=gi:11010888 /DB_XREF=est:AU149367 /CLONE=NT2RM4002171 /UG=Hs.64542 cleavage and polyadenylation specific factor 6, 68kD subunit /FL=gb:NM_007007.1 AU149367 cleavage and polyadenylation specific factor 6, 68kDa CPSF6 11052 NM_007007 /// XM_005268588 /// XM_005268589 /// XM_005268590 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202470_s_at NM_007007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007007.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 6, 68kD subunit (CPSF6), mRNA. /FEA=mRNA /GEN=CPSF6 /PROD=cleavage and polyadenylation specific factor 6,68 kD subunit /DB_XREF=gi:5901927 /UG=Hs.64542 cleavage and polyadenylation specific factor 6, 68kD subunit /FL=gb:NM_007007.1 NM_007007 cleavage and polyadenylation specific factor 6, 68kDa CPSF6 11052 NM_007007 /// XM_005268588 /// XM_005268589 /// XM_005268590 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202471_s_at NM_004135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004135.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G), mRNA. /FEA=mRNA /GEN=IDH3G /PROD=isocitrate dehydrogenase 3 (NAD+) gamma /DB_XREF=gi:4758581 /UG=Hs.75253 isocitrate dehydrogenase 3 (NAD+) gamma /FL=gb:BC001902.1 gb:BC000933.2 gb:U40272.1 gb:NM_004135.1 NM_004135 isocitrate dehydrogenase 3 (NAD+) gamma IDH3G 3421 NM_004135 /// NM_174869 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 202472_at NM_002435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002435.1 /DEF=Homo sapiens mannose phosphate isomerase (MPI), mRNA. /FEA=mRNA /GEN=MPI /PROD=mannose-6- phosphate isomerase /DB_XREF=gi:4505234 /UG=Hs.75694 mannose phosphate isomerase /FL=gb:NM_002435.1 NM_002435 mannose phosphate isomerase MPI 4351 NM_001289155 /// NM_001289156 /// NM_001289157 /// NM_002435 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004476 // mannose-6-phosphate isomerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202473_x_at AA703045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA703045 /FEA=EST /DB_XREF=gi:2706158 /DB_XREF=est:zi74d09.s1 /CLONE=IMAGE:436529 /UG=Hs.83634 host cell factor C1 (VP16-accessory protein) /FL=gb:NM_005334.1 AA703045 host cell factor C1 HCFC1 3054 NM_005334 /// XM_005274664 /// XM_006724815 /// XM_006724816 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019046 // release from viral latency // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202474_s_at NM_005334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005334.1 /DEF=Homo sapiens host cell factor C1 (VP16-accessory protein) (HCFC1), mRNA. /FEA=mRNA /GEN=HCFC1 /PROD=host cell factor C1 (VP16-accessory protein) /DB_XREF=gi:4885402 /UG=Hs.83634 host cell factor C1 (VP16-accessory protein) /FL=gb:NM_005334.1 NM_005334 host cell factor C1 HCFC1 3054 NM_005334 /// XM_005274664 /// XM_006724815 /// XM_006724816 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019046 // release from viral latency // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202475_at NM_006326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006326.1 /DEF=Homo sapiens seven transmembrane domain protein (NIFIE14), mRNA. /FEA=mRNA /GEN=NIFIE14 /PROD=seven transmembrane domain protein /DB_XREF=gi:5453781 /UG=Hs.9234 seven transmembrane domain protein /FL=gb:BC001118.1 gb:NM_006326.1 NM_006326 transmembrane protein 147 TMEM147 10430 NM_001242597 /// NM_001242598 /// NM_032635 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202476_s_at BF002130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002130 /FEA=EST /DB_XREF=gi:10702405 /DB_XREF=est:7g99f03.x1 /CLONE=IMAGE:3314621 /UG=Hs.13386 gamma-tubulin complex protein 2 /FL=gb:BC005011.1 gb:AF042379.1 gb:NM_006659.1 BF002130 tubulin, gamma complex associated protein 2 TUBGCP2 10844 NM_001256617 /// NM_001256618 /// NM_006659 /// NR_046330 /// XM_006717596 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202477_s_at NM_006659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006659.1 /DEF=Homo sapiens gamma-tubulin complex protein 2 (GCP2), mRNA. /FEA=mRNA /GEN=GCP2 /PROD=gamma-tubulin complex protein 2 /DB_XREF=gi:5729839 /UG=Hs.13386 gamma-tubulin complex protein 2 /FL=gb:BC005011.1 gb:AF042379.1 gb:NM_006659.1 NM_006659 tubulin, gamma complex associated protein 2 TUBGCP2 10844 NM_001256617 /// NM_001256618 /// NM_006659 /// NR_046330 /// XM_006717596 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202478_at NM_021643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021643.1 /DEF=Homo sapiens GS3955 protein (GS3955), mRNA. /FEA=mRNA /GEN=GS3955 /PROD=GS3955 protein /DB_XREF=gi:11056053 /UG=Hs.155418 GS3955 protein /FL=gb:NM_021643.1 gb:BC002637.1 gb:D87119.1 NM_021643 tribbles pseudokinase 2 TRIB2 28951 NM_021643 /// NR_027303 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045081 // negative regulation of interleukin-10 biosynthetic process // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity 202479_s_at BC002637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002637.1 /DEF=Homo sapiens, GS3955 protein, clone MGC:3860, mRNA, complete cds. /FEA=mRNA /PROD=GS3955 protein /DB_XREF=gi:12803604 /UG=Hs.155418 GS3955 protein /FL=gb:NM_021643.1 gb:BC002637.1 gb:D87119.1 BC002637 tribbles pseudokinase 2 TRIB2 28951 NM_021643 /// NR_027303 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045081 // negative regulation of interleukin-10 biosynthetic process // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity 202480_s_at NM_004216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004216.1 /DEF=Homo sapiens death effector domain-containing (DEDD), mRNA. /FEA=mRNA /GEN=DEDD /PROD=death effector domain-containing /DB_XREF=gi:4758143 /UG=Hs.169681 death effector domain-containing /FL=gb:AF083236.1 gb:AF043733.1 gb:AF100341.1 gb:NM_004216.1 NM_004216 death effector domain containing DEDD 9191 NM_001039711 /// NM_001039712 /// NM_004216 /// NM_032998 /// XM_005245597 /// XM_005245598 /// XM_005245599 /// XM_005245600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202481_at NM_004753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004753.1 /DEF=Homo sapiens short-chain dehydrogenasereductase 1 (SDR1), mRNA. /FEA=mRNA /GEN=SDR1 /PROD=short-chain dehydrogenasereductase 1 /DB_XREF=gi:4759083 /UG=Hs.17144 short-chain dehydrogenasereductase 1 /FL=gb:BC002730.1 gb:AF061741.1 gb:NM_004753.1 NM_004753 dehydrogenase/reductase (SDR family) member 3 DHRS3 9249 NM_004753 /// XM_005263533 /// XM_005263534 /// XM_006711036 0001523 // retinoid metabolic process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042572 // retinol metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from electronic annotation 202482_x_at AI862473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI862473 /FEA=EST /DB_XREF=gi:5526580 /DB_XREF=est:td16h04.x1 /CLONE=IMAGE:2075863 /UG=Hs.24763 RAN binding protein 1 /FL=gb:D38076.1 gb:NM_002882.2 AI862473 RAN binding protein 1 RANBP1 5902 NM_001278639 /// NM_001278640 /// NM_001278641 /// NM_002882 /// XM_006724287 /// XM_006724288 0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement 202483_s_at NM_002882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002882.2 /DEF=Homo sapiens RAN binding protein 1 (RANBP1), mRNA. /FEA=mRNA /GEN=RANBP1 /PROD=RAN binding protein 1 /DB_XREF=gi:6382077 /UG=Hs.24763 RAN binding protein 1 /FL=gb:D38076.1 gb:NM_002882.2 NM_002882 RAN binding protein 1 RANBP1 5902 NM_001278639 /// NM_001278640 /// NM_001278641 /// NM_002882 /// XM_006724287 /// XM_006724288 0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement 202484_s_at AF072242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072242.1 /DEF=Homo sapiens methyl-CpG binding protein MBD2 (MBD2) mRNA, complete cds. /FEA=mRNA /GEN=MBD2 /PROD=methyl-CpG binding protein MBD2 /DB_XREF=gi:3800792 /UG=Hs.25674 methyl-CpG binding domain protein 2 /FL=gb:AF072242.1 gb:NM_003927.2 AF072242 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202485_s_at NM_003927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003927.2 /DEF=Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1, mRNA. /FEA=mRNA /GEN=MBD2 /PROD=methyl-CpG binding domain protein 2, isoform 1 /DB_XREF=gi:7710146 /UG=Hs.25674 methyl-CpG binding domain protein 2 /FL=gb:AF072242.1 gb:NM_003927.2 NM_003927 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202486_at NM_006796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006796.1 /DEF=Homo sapiens AFG3 (ATPase family gene 3, yeast)-like 2 (AFG3L2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=AFG3L2 /PROD=AFG3-like 2 /DB_XREF=gi:5802969 /UG=Hs.29385 AFG3 (ATPase family gene 3, yeast)-like 2 /FL=gb:NM_006796.1 NM_006796 AFG3-like AAA ATPase 2 AFG3L2 10939 NM_006796 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0034982 // mitochondrial protein processing // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042407 // cristae formation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 202487_s_at NM_012412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012412.1 /DEF=Homo sapiens purine-rich element binding protein B (PURB), mRNA. /FEA=mRNA /GEN=PURB /PROD=purine-rich element binding protein B /DB_XREF=gi:6912615 /UG=Hs.301005 purine-rich element binding protein B /FL=gb:BC000098.1 gb:BC004274.1 gb:AF081192.1 gb:NM_012412.1 NM_012412 H2A histone family, member V H2AFV 94239 NM_012412 /// NM_138635 /// NM_201436 /// NM_201516 /// NM_201517 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202488_s_at NM_005971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005971.2 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 3 (FXYD3), transcript variant 1, mRNA. /FEA=mRNA /GEN=FXYD3 /PROD=MAT-8 protein, isoform 1 precursor /DB_XREF=gi:11612675 /UG=Hs.301350 FXYD domain-containing ion transport regulator 3 /FL=gb:NM_005971.2 gb:BC005238.1 NM_005971 FXYD domain containing ion transport regulator 3 FXYD3 5349 NM_001136007 /// NM_001136008 /// NM_001136009 /// NM_001136010 /// NM_001136011 /// NM_001136012 /// NM_005971 /// NM_021910 /// XM_005258992 /// XM_005258993 /// XM_005258994 /// XM_005258995 /// XM_005258996 /// XM_006723242 /// XM_006723243 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 202489_s_at BC005238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005238.1 /DEF=Homo sapiens, FXYD domain-containing ion transport regulator 3, clone MGC:12265, mRNA, complete cds. /FEA=mRNA /PROD=FXYD domain-containing ion transport regulator3 /DB_XREF=gi:13528881 /UG=Hs.301350 FXYD domain-containing ion transport regulator 3 /FL=gb:NM_005971.2 gb:BC005238.1 BC005238 FXYD domain containing ion transport regulator 3 FXYD3 5349 NM_001136007 /// NM_001136008 /// NM_001136009 /// NM_001136010 /// NM_001136011 /// NM_001136012 /// NM_005971 /// NM_021910 /// XM_005258992 /// XM_005258993 /// XM_005258994 /// XM_005258995 /// XM_005258996 /// XM_006723242 /// XM_006723243 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 202490_at AF153419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153419.2 /DEF=Homo sapiens IkappaBkinase complex-associated protein (IKBKAP) mRNA, complete cds. /FEA=mRNA /GEN=IKBKAP /PROD=IkappaBkinase complex-associated protein /DB_XREF=gi:13133509 /UG=Hs.31323 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein /FL=gb:AF153419.2 gb:AF044195.1 gb:NM_003640.1 AF153419 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein IKBKAP 8518 NM_003640 /// XM_005252285 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation 202491_s_at NM_003640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003640.1 /DEF=Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), mRNA. /FEA=mRNA /GEN=IKBKAP /PROD=inhibitor of kappa light polypeptide geneenhancer in B-cells, kinase complex-associated protein /DB_XREF=gi:4504628 /UG=Hs.31323 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein /FL=gb:AF153419.2 gb:AF044195.1 gb:NM_003640.1 NM_003640 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein IKBKAP 8518 NM_003640 /// XM_005252285 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation 202492_at NM_024085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024085.1 /DEF=Homo sapiens hypothetical protein FLJ22169 (FLJ22169), mRNA. /FEA=mRNA /GEN=FLJ22169 /PROD=hypothetical protein FLJ22169 /DB_XREF=gi:13129081 /UG=Hs.323363 hypothetical protein FLJ22169 /FL=gb:BC001206.1 gb:NM_024085.1 NM_024085 autophagy related 9A ATG9A 79065 NM_001077198 /// NM_024085 /// NR_104255 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000422 // mitochondrion degradation // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from electronic annotation /// 0034497 // protein localization to pre-autophagosomal structure // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0043588 // skin development // inferred from mutant phenotype /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // inferred from electronic annotation /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // /// 0055085 // transmembrane transport // inferred from electronic annotation 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // not recorded /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015002 // heme-copper terminal oxidase activity // inferred from electronic annotation /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 202493_x_at NM_001317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001317.2 /DEF=Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 1, mRNA. /FEA=mRNA /GEN=CSH1 /PROD=chorionic somatomammotropin hormone 1, isoform 1precursor /DB_XREF=gi:12408683 /UG=Hs.324928 chorionic somatomammotropin hormone 1 (placental lactogen) /FL=gb:NM_001317.2 gb:J00118.1 NM_001317 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSHL1 /// GH1 1442 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202494_at NM_006112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006112.1 /DEF=Homo sapiens peptidylprolyl isomerase E (cyclophilin E) (PPIE), mRNA. /FEA=mRNA /GEN=PPIE /PROD=peptidylprolyl isomerase E (cyclophilin E) /DB_XREF=gi:5174636 /UG=Hs.33251 peptidylprolyl isomerase E (cyclophilin E) /FL=gb:BC004898.1 gb:AF042385.1 gb:AF104012.1 gb:NM_006112.1 NM_006112 peptidylprolyl isomerase E (cyclophilin E) PPIE 10450 NM_001195007 /// NM_006112 /// NM_203456 /// NM_203457 /// NR_036543 /// NR_036544 /// XM_006710288 /// XM_006710289 /// XM_006710290 /// XM_006710291 /// XM_006710292 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0000413 // protein peptidyl-prolyl isomerization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202495_at NM_003192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003192.1 /DEF=Homo sapiens tubulin-specific chaperone c (TBCC), mRNA. /FEA=mRNA /GEN=TBCC /PROD=beta-tubulin cofactor C /DB_XREF=gi:4507372 /UG=Hs.75064 tubulin-specific chaperone c /FL=gb:U61234.1 gb:NM_003192.1 NM_003192 tubulin folding cofactor C TBCC 6903 NM_003192 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // traceable author statement /// 0032391 // photoreceptor connecting cilium // inferred from direct assay 0003924 // GTPase activity // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 202496_at NM_014329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014329.1 /DEF=Homo sapiens autoantigen (RCD-8), mRNA. /FEA=mRNA /GEN=RCD-8 /PROD=autoantigen /DB_XREF=gi:7657509 /UG=Hs.75682 autoantigen /FL=gb:L26339.1 gb:U17474.1 gb:NM_014329.1 NM_014329 enhancer of mRNA decapping 4 EDC4 23644 NM_014329 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202497_x_at AI631159 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI631159 /FEA=EST /DB_XREF=gi:4682489 /DB_XREF=est:ts93d05.x1 /CLONE=IMAGE:2238825 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1 AI631159 solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202498_s_at BE550486 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE550486 /FEA=EST /DB_XREF=gi:9792178 /DB_XREF=est:7a27c01.x1 /CLONE=IMAGE:3219936 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1 BE550486 solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202499_s_at NM_006931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006931.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 3 (SLC2A3), mRNA. /FEA=mRNA /GEN=SLC2A3 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 3 /DB_XREF=gi:5902089 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1 NM_006931 solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202500_at NM_006736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006736.1 /DEF=Homo sapiens heat shock protein, neuronal DNAJ-like 1 (HSJ1), mRNA. /FEA=mRNA /GEN=HSJ1 /PROD=heat shock protein, neuronal DNAJ-like 1 /DB_XREF=gi:5921580 /UG=Hs.77768 DnaJ (Hsp40) homolog, subfamily B, member 2 /FL=gb:NM_006736.1 NM_006736 DnaJ (Hsp40) homolog, subfamily B, member 2 DNAJB2 3300 NM_001039550 /// NM_006736 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from genetic interaction /// 0030308 // negative regulation of cell growth // inferred from genetic interaction /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 0090086 // negative regulation of protein deubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 202501_at NM_014268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014268.1 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 2 (MAPRE2), mRNA. /FEA=mRNA /GEN=MAPRE2 /PROD=microtubule-associated protein, RPEB family,member 2 /DB_XREF=gi:10346134 /UG=Hs.78335 microtubule-associated protein, RPEB family, member 2 /FL=gb:NM_014268.1 NM_014268 microtubule-associated protein, RP/EB family, member 2 MAPRE2 10982 NM_001143826 /// NM_001143827 /// NM_001256420 /// NM_014268 /// NR_046177 /// XM_006722375 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 202502_at NM_000016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000016.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain (ACADM), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADM /PROD=acyl-Coenzyme A dehydrogenase, C-4 to C-12straight chain proenzyme /DB_XREF=gi:4557230 /UG=Hs.79158 acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain /FL=gb:BC005377.1 gb:M16827.1 gb:NM_000016.1 gb:AF251043.1 NM_000016 acyl-CoA dehydrogenase, C-4 to C-12 straight chain ACADM 34 NM_000016 /// NM_001127328 /// NM_001286042 /// NM_001286043 /// NM_001286044 /// NR_022013 0001889 // liver development // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from mutant phenotype /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from direct assay /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from mutant phenotype /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from mutant phenotype /// 0051791 // medium-chain fatty acid metabolic process // inferred from direct assay /// 0051793 // medium-chain fatty acid catabolic process // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from direct assay /// 0003995 // acyl-CoA dehydrogenase activity // inferred from mutant phenotype /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0070991 // medium-chain-acyl-CoA dehydrogenase activity // inferred from direct assay 202503_s_at NM_014736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014736.1 /DEF=Homo sapiens KIAA0101 gene product (KIAA0101), mRNA. /FEA=mRNA /GEN=KIAA0101 /PROD=KIAA0101 gene product /DB_XREF=gi:7661905 /UG=Hs.81892 KIAA0101 gene product /FL=gb:D14657.1 gb:NM_014736.1 NM_014736 KIAA0101 KIAA0101 9768 NM_001029989 /// NM_014736 /// NR_109934 0006260 // DNA replication // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0019985 // translesion synthesis // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202504_at NM_012101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012101.1 /DEF=Homo sapiens ataxia-telangiectasia group D-associated protein (ATDC), mRNA. /FEA=mRNA /GEN=ATDC /PROD=ataxia-telangiectasia group D-associatedprotein /DB_XREF=gi:6912249 /UG=Hs.82237 ataxia-telangiectasia group D-associated protein /FL=gb:AF230388.1 gb:L24203.1 gb:NM_012101.1 NM_012101 tripartite motif containing 29 TRIM29 23650 NM_012101 /// NM_058193 /// XM_005271487 /// XM_005271490 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 1900181 // negative regulation of protein localization to nucleus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0002039 // p53 binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202505_at NM_003092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003092.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide B (SNRPB2), mRNA. /FEA=mRNA /GEN=SNRPB2 /PROD=small nuclear ribonucleoprotein polypeptide B /DB_XREF=gi:4507122 /UG=Hs.82575 small nuclear ribonucleoprotein polypeptide B /FL=gb:M15841.1 gb:NM_003092.1 NM_003092 small nuclear ribonucleoprotein polypeptide B SNRPB2 6629 NM_003092 /// NM_198220 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005686 // U2 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from electronic annotation 202506_at NM_006751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006751.1 /DEF=Homo sapiens sperm specific antigen 2 (SSFA2), mRNA. /FEA=mRNA /GEN=SSFA2 /PROD=sperm specific antigen 2 /DB_XREF=gi:5803178 /UG=Hs.82767 sperm specific antigen 2 /FL=gb:M61199.1 gb:NM_006751.1 NM_006751 sperm specific antigen 2 SSFA2 6744 NM_001130445 /// NM_001287503 /// NM_001287504 /// NM_001287505 /// NM_006751 /// NR_109843 /// XM_005246812 /// XM_005246813 /// XR_241319 /// XR_241320 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation 202507_s_at L19760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L19760.1 /DEF=Human nerve-terminal protein (isoform SNAP25A) mRNA, complete cds. /FEA=mRNA /GEN=SNAP /PROD=nerve terminal protein /DB_XREF=gi:307425 /UG=Hs.84389 synaptosomal-associated protein, 25kD /FL=gb:D21267.1 gb:L19760.1 gb:L19761.1 gb:NM_003081.1 L19760 synaptosomal-associated protein, 25kDa SNAP25 6616 NM_003081 /// NM_130811 /// XM_005260808 /// XM_005260810 /// XM_006723614 0001504 // neurotransmitter uptake // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202508_s_at NM_003081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003081.1 /DEF=Homo sapiens synaptosomal-associated protein, 25kD (SNAP25), mRNA. /FEA=mRNA /GEN=SNAP25 /PROD=synaptosomal-associated protein (25kD) /DB_XREF=gi:4507098 /UG=Hs.84389 synaptosomal-associated protein, 25kD /FL=gb:D21267.1 gb:L19760.1 gb:L19761.1 gb:NM_003081.1 NM_003081 synaptosomal-associated protein, 25kDa SNAP25 6616 NM_003081 /// NM_130811 /// XM_005260808 /// XM_005260810 /// XM_006723614 0001504 // neurotransmitter uptake // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202509_s_at AI862445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI862445 /FEA=EST /DB_XREF=gi:5526552 /DB_XREF=est:td16e10.x1 /CLONE=IMAGE:2075850 /UG=Hs.101382 tumor necrosis factor, alpha-induced protein 2 /FL=gb:M92357.1 gb:NM_006291.1 AI862445 tumor necrosis factor, alpha-induced protein 2 TNFAIP2 7127 NM_006291 /// XM_006720243 0001525 // angiogenesis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202510_s_at NM_006291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006291.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 2 (TNFAIP2), mRNA. /FEA=mRNA /GEN=TNFAIP2 /PROD=tumor necrosis factor, alpha-induced protein 2 /DB_XREF=gi:5454133 /UG=Hs.101382 tumor necrosis factor, alpha-induced protein 2 /FL=gb:M92357.1 gb:NM_006291.1 NM_006291 tumor necrosis factor, alpha-induced protein 2 TNFAIP2 7127 NM_006291 /// XM_006720243 0001525 // angiogenesis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202511_s_at AK001899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001899.1 /DEF=Homo sapiens cDNA FLJ11037 fis, clone PLACE1004316, highly similar to H.sapiens mRNA for apoptosis specific protein. /FEA=mRNA /DB_XREF=gi:7023451 /UG=Hs.11171 APG5 (autophagy 5, S. cerevisiae)-like /FL=gb:NM_004849.1 AK001899 autophagy related 5 ATG5 9474 NM_001286106 /// NM_001286107 /// NM_001286108 /// NM_001286111 /// NM_004849 /// NR_104402 /// NR_104403 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // not recorded /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002739 // regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // not recorded /// 0006914 // autophagy // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0030435 // sporulation resulting in formation of a cellular spore // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from sequence or structural similarity /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // traceable author statement /// 0048840 // otolith development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // not recorded 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // not recorded 202512_s_at NM_004849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004849.1 /DEF=Homo sapiens APG5 (autophagy 5, S. cerevisiae)-like (APG5L), mRNA. /FEA=mRNA /GEN=APG5L /PROD=APG5 (autophagy 5, S. cerevisiae)-like /DB_XREF=gi:4757797 /UG=Hs.11171 APG5 (autophagy 5, S. cerevisiae)-like /FL=gb:NM_004849.1 NM_004849 autophagy related 5 ATG5 9474 NM_001286106 /// NM_001286107 /// NM_001286108 /// NM_001286111 /// NM_004849 /// NR_104402 /// NR_104403 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // not recorded /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002739 // regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // not recorded /// 0006914 // autophagy // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0030435 // sporulation resulting in formation of a cellular spore // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from sequence or structural similarity /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // traceable author statement /// 0048840 // otolith development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // not recorded 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // not recorded 202513_s_at NM_006245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006245.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), delta isoform (PPP2R5D), mRNA. /FEA=mRNA /GEN=PPP2R5D /PROD=protein phosphatase 2, regulatory subunit B(B56), delta isoform /DB_XREF=gi:5453953 /UG=Hs.118244 protein phosphatase 2, regulatory subunit B (B56), delta isoform /FL=gb:BC001095.1 gb:L76702.1 gb:AB000634.1 gb:NM_006245.1 NM_006245 protein phosphatase 2, regulatory subunit B', delta PPP2R5D 5528 NM_001270476 /// NM_006245 /// NM_180976 /// NM_180977 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 202514_at AW139131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139131 /FEA=EST /DB_XREF=gi:6143449 /DB_XREF=est:UI-H-BI1-aet-a-12-0-UI.s1 /CLONE=IMAGE:2720183 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1 AW139131 discs, large homolog 1 (Drosophila) DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202515_at BG251175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG251175 /FEA=EST /DB_XREF=gi:12760991 /DB_XREF=est:602364982F1 /CLONE=IMAGE:4473165 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1 BG251175 discs, large homolog 1 (Drosophila) DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202516_s_at NM_004087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004087.1 /DEF=Homo sapiens discs, large (Drosophila) homolog 1 (DLG1), mRNA. /FEA=mRNA /GEN=DLG1 /PROD=discs, large (Drosophila) homolog 1 /DB_XREF=gi:4758161 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1 NM_004087 discs, large homolog 1 (Drosophila) DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202517_at NM_001313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001313.1 /DEF=Homo sapiens collapsin response mediator protein 1 (CRMP1), mRNA. /FEA=mRNA /GEN=CRMP1 /PROD=collapsin response mediator protein 1 /DB_XREF=gi:4503050 /UG=Hs.155392 collapsin response mediator protein 1 /FL=gb:BC000252.1 gb:D78012.1 gb:NM_001313.1 gb:U17278.1 NM_001313 collapsin response mediator protein 1 CRMP1 1400 NM_001014809 /// NM_001288661 /// NM_001288662 /// NM_001313 /// XM_005247940 /// XM_005247941 /// XM_005247942 /// XM_005247943 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 202518_at NM_001707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001707.1 /DEF=Homo sapiens B-cell CLLlymphoma 7B (BCL7B), mRNA. /FEA=mRNA /GEN=BCL7B /PROD=B-cell CLLlymphoma 7B /DB_XREF=gi:4502384 /UG=Hs.16269 B-cell CLLlymphoma 7B /FL=gb:BC000956.2 gb:BC001967.1 gb:NM_001707.1 NM_001707 B-cell CLL/lymphoma 7B BCL7B 9275 NM_001197244 /// NM_001707 /// NM_138707 /// NR_036682 /// XM_006716177 0003779 // actin binding // non-traceable author statement 202519_at NM_014938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014938.1 /DEF=Homo sapiens KIAA0867 protein (MONDOA), mRNA. /FEA=mRNA /GEN=MONDOA /PROD=MondoA protein /DB_XREF=gi:7662347 /UG=Hs.52081 KIAA0867 protein /FL=gb:AB020674.1 gb:NM_014938.1 NM_014938 MLX interacting protein MLXIP 22877 NM_014938 /// XM_006719290 /// XM_006719291 /// XM_006719292 /// XM_006719293 /// XM_006719294 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202520_s_at NM_000249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000249.1 /DEF=Homo sapiens mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) (MLH1), mRNA. /FEA=mRNA /GEN=MLH1 /PROD=mutL homolog 1 /DB_XREF=gi:4557756 /UG=Hs.57301 mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) /FL=gb:NM_000249.1 gb:U07343.1 gb:U07418.1 NM_000249 mutL homolog 1 MLH1 4292 NM_000249 /// NM_001167617 /// NM_001167618 /// NM_001167619 /// NM_001258271 /// NM_001258273 /// NM_001258274 /// XM_005265161 /// XM_005265163 /// XM_005265164 /// XM_005265166 /// XR_427268 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0000712 // resolution of meiotic recombination intermediates // inferred from electronic annotation /// 0002204 // somatic recombination of immunoglobulin genes involved in immune response // inferred from electronic annotation /// 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007060 // male meiosis chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // /// 0007140 // male meiosis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0043060 // meiotic metaphase I plate congression // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0045950 // negative regulation of mitotic recombination // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0051257 // spindle midzone assembly involved in meiosis // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005712 // chiasma // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0032300 // mismatch repair complex // /// 0032389 // MutLalpha complex // not recorded /// 0032390 // MutLbeta complex // 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032137 // guanine/thymine mispair binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from electronic annotation 202521_at NM_006565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006565.1 /DEF=Homo sapiens CCCTC-binding factor (zinc finger protein) (CTCF), mRNA. /FEA=mRNA /GEN=CTCF /PROD=CCCTC-binding factor (zinc finger protein) /DB_XREF=gi:5729789 /UG=Hs.57419 CCCTC-binding factor (zinc finger protein) /FL=gb:NM_006565.1 gb:U25435.1 NM_006565 CCCTC-binding factor (zinc finger protein) CTCF 10664 NM_001191022 /// NM_006565 /// XM_005255775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0031060 // regulation of histone methylation // inferred from electronic annotation /// 0035065 // regulation of histone acetylation // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0040030 // regulation of molecular function, epigenetic // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0070602 // regulation of centromeric sister chromatid cohesion // non-traceable author statement 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0043035 // chromatin insulator sequence binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202522_at AL031591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031591 /DEF=Human DNA sequence from clone RP3-353E16 on chromosome 22q11.22-12.3 Contains the 5 part of the MN1 gene for meningioma (disrupted in balanced translocation) 1, the PITPNB gene for phosphatidylinositol transfer protein beta, ESTs, STSs, GSSs and ... /FEA=mRNA /DB_XREF=gi:6006484 /UG=Hs.7370 phosphotidylinositol transfer protein, beta /FL=gb:D30037.1 gb:NM_012399.1 AL031591 phosphatidylinositol transfer protein, beta PITPNB 23760 NM_001284277 /// NM_001284278 /// NM_012399 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015914 // phospholipid transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 202523_s_at AI952009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI952009 /FEA=EST /DB_XREF=gi:5744319 /DB_XREF=est:wx40f07.x1 /CLONE=IMAGE:2546149 /UG=Hs.74583 KIAA0275 gene product /FL=gb:D87465.1 gb:NM_014767.1 AI952009 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 SPOCK2 9806 NM_001134434 /// NM_001244950 /// NM_014767 /// XM_005270302 0007165 // signal transduction // inferred from electronic annotation /// 0007416 // synapse assembly // non-traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202524_s_at NM_014767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014767.1 /DEF=Homo sapiens KIAA0275 gene product (KIAA0275), mRNA. /FEA=mRNA /GEN=KIAA0275 /PROD=KIAA0275 gene product /DB_XREF=gi:7662035 /UG=Hs.74583 KIAA0275 gene product /FL=gb:D87465.1 gb:NM_014767.1 NM_014767 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 SPOCK2 9806 NM_001134434 /// NM_001244950 /// NM_014767 /// XM_005270302 0007165 // signal transduction // inferred from electronic annotation /// 0007416 // synapse assembly // non-traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202525_at NM_002773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002773.1 /DEF=Homo sapiens protease, serine, 8 (prostasin) (PRSS8), mRNA. /FEA=mRNA /GEN=PRSS8 /PROD=protease, serine, 8 (prostasin) /DB_XREF=gi:4506152 /UG=Hs.75799 protease, serine, 8 (prostasin) /FL=gb:BC001462.1 gb:NM_002773.1 gb:L41351.1 NM_002773 protease, serine, 8 PRSS8 5652 NM_002773 0006508 // proteolysis // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 202526_at U44378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U44378.1 /DEF=Human homozygous deletion target in pancreatic carcinoma (DPC4) mRNA, complete cds. /FEA=mRNA /GEN=DPC4 /PROD=Dpc4 /DB_XREF=gi:1163233 /UG=Hs.75862 MAD (mothers against decapentaplegic, Drosophila) homolog 4 /FL=gb:U44378.1 gb:BC002379.1 gb:NM_005359.1 U44378 SMAD family member 4 SMAD4 4089 NM_005359 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003190 // atrioventricular valve formation // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003251 // positive regulation of cell proliferation involved in heart valve morphogenesis // inferred from electronic annotation /// 0003279 // cardiac septum development // inferred from electronic annotation /// 0003360 // brainstem development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036302 // atrioventricular canal development // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051797 // regulation of hair follicle development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060956 // endocardial cell differentiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0030616 // transforming growth factor beta receptor, common-partner cytoplasmic mediator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 202527_s_at NM_005359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005359.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 4 (MADH4), mRNA. /FEA=mRNA /GEN=MADH4 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 4 /DB_XREF=gi:4885456 /UG=Hs.75862 MAD (mothers against decapentaplegic, Drosophila) homolog 4 /FL=gb:U44378.1 gb:BC002379.1 gb:NM_005359.1 NM_005359 SMAD family member 4 SMAD4 4089 NM_005359 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003190 // atrioventricular valve formation // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003251 // positive regulation of cell proliferation involved in heart valve morphogenesis // inferred from electronic annotation /// 0003279 // cardiac septum development // inferred from electronic annotation /// 0003360 // brainstem development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036302 // atrioventricular canal development // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051797 // regulation of hair follicle development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060956 // endocardial cell differentiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0030616 // transforming growth factor beta receptor, common-partner cytoplasmic mediator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 202528_at NM_000403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000403.2 /DEF=Homo sapiens galactose-4-epimerase, UDP- (GALE), mRNA. /FEA=mRNA /GEN=GALE /PROD=UDP-galactose-4-epimerase /DB_XREF=gi:9945333 /UG=Hs.76057 galactose-4-epimerase, UDP- /FL=gb:BC001273.1 gb:L41668.1 gb:NM_000403.2 NM_000403 UDP-galactose-4-epimerase GALE 2582 NM_000403 /// NM_001008216 /// NM_001127621 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019388 // galactose catabolic process // inferred from direct assay /// 0019388 // galactose catabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0003978 // UDP-glucose 4-epimerase activity // not recorded /// 0003978 // UDP-glucose 4-epimerase activity // inferred from direct assay /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050662 // coenzyme binding // inferred from electronic annotation 202529_at NM_002766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002766.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPSAP1), mRNA. /FEA=mRNA /GEN=PRPSAP1 /PROD=phosphoribosyl pyrophosphatesynthetase-associated protein 1 /DB_XREF=gi:4506130 /UG=Hs.77498 phosphoribosyl pyrophosphate synthetase-associated protein 1 /FL=gb:D61391.1 gb:NM_002766.1 NM_002766 phosphoribosyl pyrophosphate synthetase-associated protein 1 PRPSAP1 5635 NM_002766 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0033673 // negative regulation of kinase activity // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0019900 // kinase binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 202530_at NM_001315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001315.1 /DEF=Homo sapiens mitogen-activated protein kinase 14 (MAPK14), mRNA. /FEA=mRNA /GEN=MAPK14 /PROD=mitogen-activated protein kinase 14 /DB_XREF=gi:4503068 /UG=Hs.79107 mitogen-activated protein kinase 14 /FL=gb:NM_001315.1 gb:L35263.1 NM_001315 mitogen-activated protein kinase 14 MAPK14 1432 NM_001315 /// NM_139012 /// NM_139013 /// NM_139014 /// XM_006714998 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038066 // p38MAPK cascade // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090400 // stress-induced premature senescence // inferred from mutant phenotype /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005623 // cell // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity 202531_at NM_002198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002198.1 /DEF=Homo sapiens interferon regulatory factor 1 (IRF1), mRNA. /FEA=mRNA /GEN=IRF1 /PROD=interferon regulatory factor 1 /DB_XREF=gi:4504720 /UG=Hs.80645 interferon regulatory factor 1 /FL=gb:NM_002198.1 NM_002198 interferon regulatory factor 1 IRF1 3659 NM_002198 /// XR_427711 0002376 // immune system process // inferred from electronic annotation /// 0002819 // regulation of adaptive immune response // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0034124 // regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0035458 // cellular response to interferon-beta // inferred from direct assay /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045088 // regulation of innate immune response // traceable author statement /// 0045590 // negative regulation of regulatory T cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2000564 // regulation of CD8-positive, alpha-beta T cell proliferation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202532_s_at BC000192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000192.1 /DEF=Homo sapiens, dihydrofolate reductase, clone MGC:857, mRNA, complete cds. /FEA=mRNA /PROD=dihydrofolate reductase /DB_XREF=gi:12652874 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2 BC000192 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202533_s_at BC003584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003584.1 /DEF=Homo sapiens, dihydrofolate reductase, clone MGC:3153, mRNA, complete cds. /FEA=mRNA /PROD=dihydrofolate reductase /DB_XREF=gi:13097773 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2 BC003584 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202534_x_at NM_000791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000791.2 /DEF=Homo sapiens dihydrofolate reductase (DHFR), mRNA. /FEA=mRNA /GEN=DHFR /PROD=dihydrofolate reductase /DB_XREF=gi:7262376 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2 NM_000791 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202535_at NM_003824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003824.1 /DEF=Homo sapiens Fas (TNFRSF6)-associated via death domain (FADD), mRNA. /FEA=mRNA /GEN=FADD /PROD=Fas (TNFRSF6)-associated via death domain /DB_XREF=gi:4505228 /UG=Hs.86131 Fas (TNFRSF6)-associated via death domain /FL=gb:BC000334.1 gb:NM_003824.1 gb:U24231.1 NM_003824 Fas (TNFRSF6)-associated via death domain FADD 8772 NM_003824 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002821 // positive regulation of adaptive immune response // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036462 // TRAIL-activated apoptotic signaling pathway // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070236 // negative regulation of activation-induced cell death of T cells // inferred from sequence or structural similarity /// 0070265 // necrotic cell death // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000454 // positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031264 // death-inducing signaling complex // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from physical interaction /// 0005123 // death receptor binding // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202536_at AK002165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002165.1 /DEF=Homo sapiens cDNA FLJ11303 fis, clone PLACE1009995, highly similar to Homo sapiens mRNA; cDNA DKFZp564O123. /FEA=mRNA /DB_XREF=gi:7023876 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1 AK002165 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202537_s_at AF151842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151842.1 /DEF=Homo sapiens CGI-84 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-84 protein /DB_XREF=gi:4929636 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1 AF151842 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202538_s_at NM_014043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014043.1 /DEF=Homo sapiens DKFZP564O123 protein (DKFZP564O123), mRNA. /FEA=mRNA /GEN=DKFZP564O123 /PROD=DKFZP564O123 protein /DB_XREF=gi:7661633 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1 NM_014043 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202539_s_at AL518627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL518627 /FEA=EST /DB_XREF=gi:12782120 /DB_XREF=est:AL518627 /CLONE=CS0DA009YG15 (3 prime) /UG=Hs.11899 3-hydroxy-3-methylglutaryl-Coenzyme A reductase /FL=gb:M11058.1 gb:NM_000859.1 AL518627 3-hydroxy-3-methylglutaryl-CoA reductase HMGCR 3156 NM_000859 /// NM_001130996 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006743 // ubiquinone metabolic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from electronic annotation /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004420 // hydroxymethylglutaryl-CoA reductase (NADPH) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042282 // hydroxymethylglutaryl-CoA reductase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from direct assay 202540_s_at NM_000859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000859.1 /DEF=Homo sapiens 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGCR), mRNA. /FEA=mRNA /GEN=HMGCR /PROD=3-hydroxy-3-methylglutaryl-Coenzyme A reductase /DB_XREF=gi:4557642 /UG=Hs.11899 3-hydroxy-3-methylglutaryl-Coenzyme A reductase /FL=gb:M11058.1 gb:NM_000859.1 NM_000859 3-hydroxy-3-methylglutaryl-CoA reductase HMGCR 3156 NM_000859 /// NM_001130996 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006743 // ubiquinone metabolic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from electronic annotation /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004420 // hydroxymethylglutaryl-CoA reductase (NADPH) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042282 // hydroxymethylglutaryl-CoA reductase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from direct assay 202541_at BF589679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF589679 /FEA=EST /DB_XREF=gi:11682003 /DB_XREF=est:naa08b05.x1 /CLONE=IMAGE:3253977 /UG=Hs.146401 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) /FL=gb:NM_004757.1 gb:U10117.1 BF589679 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 AIMP1 9255 NM_001142415 /// NM_001142416 /// NM_004757 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202542_s_at NM_004757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004757.1 /DEF=Homo sapiens small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) (SCYE1), mRNA. /FEA=mRNA /GEN=SCYE1 /PROD=small inducible cytokine subfamily E, member 1 /DB_XREF=gi:4758265 /UG=Hs.146401 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) /FL=gb:NM_004757.1 gb:U10117.1 NM_004757 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 AIMP1 9255 NM_001142415 /// NM_001142416 /// NM_004757 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202543_s_at BC005359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005359.1 /DEF=Homo sapiens, glia maturation factor, beta, clone MGC:12462, mRNA, complete cds. /FEA=mRNA /PROD=glia maturation factor, beta /DB_XREF=gi:13529184 /UG=Hs.151413 glia maturation factor, beta /FL=gb:BC005359.1 gb:M86492.1 gb:AB001106.1 gb:NM_004124.1 BC005359 glia maturation factor, beta GMFB 2764 NM_004124 /// XM_005267541 /// XM_006720118 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 202544_at NM_004124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004124.1 /DEF=Homo sapiens glia maturation factor, beta (GMFB), mRNA. /FEA=mRNA /GEN=GMFB /PROD=glia maturation factor, beta /DB_XREF=gi:4758441 /UG=Hs.151413 glia maturation factor, beta /FL=gb:BC005359.1 gb:M86492.1 gb:AB001106.1 gb:NM_004124.1 NM_004124 glia maturation factor, beta GMFB 2764 NM_004124 /// XM_005267541 /// XM_006720118 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 202545_at NM_006254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006254.1 /DEF=Homo sapiens protein kinase C, delta (PRKCD), mRNA. /FEA=mRNA /GEN=PRKCD /PROD=protein kinase C, delta /DB_XREF=gi:5453969 /UG=Hs.155342 protein kinase C, delta /FL=gb:L07860.1 gb:L07861.1 gb:D10495.1 gb:NM_006254.1 NM_006254 protein kinase C, delta PRKCD 5580 NM_006254 /// NM_212539 /// XM_006713257 /// XM_006713258 /// XM_006713259 0001666 // response to hypoxia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0032091 // negative regulation of protein binding // traceable author statement /// 0032613 // interleukin-10 production // inferred from electronic annotation /// 0032615 // interleukin-12 production // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from mutant phenotype /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0042119 // neutrophil activation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // non-traceable author statement /// 0051490 // negative regulation of filopodium assembly // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0090331 // negative regulation of platelet aggregation // inferred from sequence or structural similarity /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900163 // positive regulation of phospholipid scramblase activity // inferred from mutant phenotype /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from mutant phenotype /// 2000753 // positive regulation of glucosylceramide catabolic process // inferred from mutant phenotype /// 2000755 // positive regulation of sphingomyelin catabolic process // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004699 // calcium-independent protein kinase C activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070976 // TIR domain binding // inferred from electronic annotation 202546_at NM_003761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003761.1 /DEF=Homo sapiens vesicle-associated membrane protein 8 (endobrevin) (VAMP8), mRNA. /FEA=mRNA /GEN=VAMP8 /PROD=vesicle-associated membrane protein 8 /DB_XREF=gi:4507864 /UG=Hs.172684 vesicle-associated membrane protein 8 (endobrevin) /FL=gb:BC001634.1 gb:AF053233.1 gb:NM_003761.1 NM_003761 vesicle-associated membrane protein 8 VAMP8 8673 NM_003761 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0046718 // viral entry into host cell // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 202547_s_at AA778936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA778936 /FEA=EST /DB_XREF=gi:2838267 /DB_XREF=est:zj38h05.s1 /CLONE=IMAGE:452601 /UG=Hs.172813 PAK-interacting exchange factor beta /FL=gb:D63476.1 gb:NM_003899.1 AA778936 Rho guanine nucleotide exchange factor (GEF) 7 ARHGEF7 8874 NM_001113511 /// NM_001113512 /// NM_001113513 /// NM_003899 /// NM_145735 /// XM_005254085 /// XM_005254086 /// XM_005254087 /// XM_005254088 /// XM_005254089 /// XM_005254090 /// XM_005254091 /// XM_005254092 /// XM_005254093 /// XM_005254094 /// XM_005254095 /// XM_006719956 /// XM_006719957 /// XM_006719958 /// XM_006719959 /// XM_006719960 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 202548_s_at NM_003899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003899.1 /DEF=Homo sapiens PAK-interacting exchange factor beta (P85SPR), mRNA. /FEA=mRNA /GEN=P85SPR /PROD=PAK-interacting exchange factor beta /DB_XREF=gi:4505572 /UG=Hs.172813 PAK-interacting exchange factor beta /FL=gb:D63476.1 gb:NM_003899.1 NM_003899 Rho guanine nucleotide exchange factor (GEF) 7 ARHGEF7 8874 NM_001113511 /// NM_001113512 /// NM_001113513 /// NM_003899 /// NM_145735 /// XM_005254085 /// XM_005254086 /// XM_005254087 /// XM_005254088 /// XM_005254089 /// XM_005254090 /// XM_005254091 /// XM_005254092 /// XM_005254093 /// XM_005254094 /// XM_005254095 /// XM_006719956 /// XM_006719957 /// XM_006719958 /// XM_006719959 /// XM_006719960 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 202549_at AK025720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025720.1 /DEF=Homo sapiens cDNA: FLJ22067 fis, clone HEP11115F, highly similar to AF086629 Homo sapiens VAMP-associated protein C (VAP-C) mRNA. /FEA=mRNA /DB_XREF=gi:10438329 /UG=Hs.182625 VAMP (vesicle-associated membrane protein)-associated protein B and C /FL=gb:BC001712.1 gb:AF086628.1 gb:NM_004738.1 gb:AF160212.1 AK025720 VAMP (vesicle-associated membrane protein)-associated protein B and C VAPB 9217 NM_001195677 /// NM_004738 /// NR_036633 /// XM_006723888 0006665 // sphingolipid metabolic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay 202550_s_at NM_004738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004738.1 /DEF=Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), mRNA. /FEA=mRNA /GEN=VAPB /PROD=VAMP (vesicle-associated membraneprotein)-associated protein B and C /DB_XREF=gi:4759301 /UG=Hs.182625 VAMP (vesicle-associated membrane protein)-associated protein B and C /FL=gb:BC001712.1 gb:AF086628.1 gb:NM_004738.1 gb:AF160212.1 NM_004738 VAMP (vesicle-associated membrane protein)-associated protein B and C VAPB 9217 NM_001195677 /// NM_004738 /// NR_036633 /// XM_006723888 0006665 // sphingolipid metabolic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay 202551_s_at BG546884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG546884 /FEA=EST /DB_XREF=gi:13545549 /DB_XREF=est:602574066F1 /CLONE=IMAGE:4702049 /UG=Hs.19280 cysteine-rich motor neuron 1 /FL=gb:NM_016441.1 gb:AF167706.1 BG546884 cysteine rich transmembrane BMP regulator 1 (chordin-like) /// uncharacterized LOC101929500 CRIM1 /// LOC101929500 51232 /// 101929500 NM_016441 /// XM_005264357 /// XM_005264358 /// XR_244983 /// XR_249109 /// XR_251054 /// XR_426983 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay 202552_s_at NM_016441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016441.1 /DEF=Homo sapiens cysteine-rich motor neuron 1 (CRIM1), mRNA. /FEA=mRNA /GEN=CRIM1 /PROD=cysteine-rich motor neuron 1 /DB_XREF=gi:10092638 /UG=Hs.19280 cysteine-rich motor neuron 1 /FL=gb:NM_016441.1 gb:AF167706.1 NM_016441 cysteine rich transmembrane BMP regulator 1 (chordin-like) /// uncharacterized LOC101929500 CRIM1 /// LOC101929500 51232 /// 101929500 NM_016441 /// XM_005264357 /// XM_005264358 /// XR_244983 /// XR_249109 /// XR_251054 /// XR_426983 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay 202553_s_at NM_015484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015484.1 /DEF=Homo sapiens GCIP-interacting protein p29 (P29), mRNA. /FEA=mRNA /GEN=P29 /PROD=GCIP-interacting protein p29 /DB_XREF=gi:7661635 /UG=Hs.20013 GCIP-interacting protein p29 /FL=gb:AF273089.1 gb:AL080166.1 gb:NM_015484.1 NM_015484 SYF2 pre-mRNA-splicing factor SYF2 25949 NM_015484 /// NM_207170 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202554_s_at AL527430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL527430 /FEA=EST /DB_XREF=gi:12790923 /DB_XREF=est:AL527430 /CLONE=CS0DC021YF13 (5 prime) /UG=Hs.2006 glutathione S-transferase M3 (brain) /FL=gb:BC000088.1 gb:J05459.1 gb:NM_000849.1 AL527430 glutathione S-transferase mu 3 (brain) GSTM3 2947 NM_000849 /// NR_024537 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008065 // establishment of blood-nerve barrier // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 202555_s_at NM_005965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005965.1 /DEF=Homo sapiens myosin, light polypeptide kinase (MYLK), mRNA. /FEA=mRNA /GEN=MYLK /PROD=myosin, light polypeptide kinase /DB_XREF=gi:5174600 /UG=Hs.211582 myosin, light polypeptide kinase /FL=gb:AB037663.1 gb:NM_005965.1 gb:AF069601.2 NM_005965 myosin light chain kinase MYLK 4638 NM_005965 /// NM_053025 /// NM_053026 /// NM_053027 /// NM_053028 /// NM_053029 /// NM_053030 /// NM_053031 /// NM_053032 /// XM_005247492 /// XM_005247493 /// XM_005247494 /// XM_006713649 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // not recorded /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007015 // actin filament organization // not recorded /// 0014820 // tonic smooth muscle contraction // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032060 // bleb assembly // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060414 // aorta smooth muscle tissue morphogenesis // inferred from mutant phenotype /// 0071476 // cellular hypotonic response // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004687 // myosin light chain kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202556_s_at NM_006337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006337.1 /DEF=Homo sapiens microspherule protein 1 (MCRS1), mRNA. /FEA=mRNA /GEN=MCRS1 /PROD=microspherule protein 1 /DB_XREF=gi:5453693 /UG=Hs.25313 microspherule protein 1 /FL=gb:AF068007.1 gb:NM_006337.1 NM_006337 microspherule protein 1 MCRS1 10445 NM_001012300 /// NM_001278341 /// NM_006337 /// XM_005268572 /// XM_005268573 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0031011 // Ino80 complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202557_at AI718418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI718418 /FEA=EST /DB_XREF=gi:5035674 /DB_XREF=est:as43b01.x1 /CLONE=IMAGE:2319913 /UG=Hs.288799 stress 70 protein chaperone, microsome-associated, 60kD /FL=gb:U04735.1 gb:NM_006948.1 AI718418 heat shock protein 70kDa family, member 13 HSPA13 6782 NM_006948 0000902 // cell morphogenesis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202558_s_at NM_006948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006948.1 /DEF=Homo sapiens stress 70 protein chaperone, microsome-associated, 60kD (STCH), mRNA. /FEA=mRNA /GEN=STCH /PROD=stress 70 protein chaperone,microsome-associated, 60kD /DB_XREF=gi:5902125 /UG=Hs.288799 stress 70 protein chaperone, microsome-associated, 60kD /FL=gb:U04735.1 gb:NM_006948.1 NM_006948 heat shock protein 70kDa family, member 13 HSPA13 6782 NM_006948 0000902 // cell morphogenesis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202559_x_at AW005776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW005776 /FEA=EST /DB_XREF=gi:5854554 /DB_XREF=est:wz89d09.x1 /CLONE=IMAGE:2566001 /UG=Hs.323817 DKFZP547E1010 protein /FL=gb:NM_015607.1 AW005776 chromatin target of PRMT1 CHTOP 26097 NM_001206612 /// NM_001244664 /// NM_015607 /// XM_005245085 /// XM_005245086 /// XM_006711269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202560_s_at NM_015607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015607.1 /DEF=Homo sapiens DKFZP547E1010 protein (DKFZP547E1010), mRNA. /FEA=mRNA /GEN=DKFZP547E1010 /PROD=DKFZP547E1010 protein /DB_XREF=gi:7661589 /UG=Hs.323817 DKFZP547E1010 protein /FL=gb:NM_015607.1 NM_015607 chromatin target of PRMT1 CHTOP 26097 NM_001206612 /// NM_001244664 /// NM_015607 /// XM_005245085 /// XM_005245086 /// XM_006711269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202561_at AF070613 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070613.1 /DEF=Homo sapiens clone 24585 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387995 /UG=Hs.131814 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase /FL=gb:AF082556.1 gb:NM_003747.1 AF070613 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase TNKS 8658 NM_003747 /// XM_006716263 0000209 // protein polyubiquitination // inferred from direct assay /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0032210 // regulation of telomere maintenance via telomerase // inferred by curator /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from direct assay /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051225 // spindle assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0070212 // protein poly-ADP-ribosylation // inferred from direct assay /// 0070213 // protein auto-ADP-ribosylation // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000242 // pericentriolar material // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // traceable author statement 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202562_s_at AL136658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136658.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564H0664 (from clone DKFZp564H0664); complete cds. /FEA=mRNA /GEN=DKFZp564H0664 /PROD=hypothetical protein /DB_XREF=gi:12052839 /UG=Hs.15106 chromosome 14 open reading frame 1 /FL=gb:AL136658.1 gb:AF136971.1 gb:BC002444.1 gb:AF134159.2 gb:NM_007176.1 AL136658 chromosome 14 open reading frame 1 C14orf1 11161 NM_007176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030133 // transport vesicle // inferred from direct assay 202563_at NM_007176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007176.1 /DEF=Homo sapiens chromosome 14 open reading frame 1 (C14ORF1), mRNA. /FEA=mRNA /GEN=C14ORF1 /PROD=chromosome 14 open reading frame 1 /DB_XREF=gi:6005718 /UG=Hs.15106 chromosome 14 open reading frame 1 /FL=gb:AL136658.1 gb:AF136971.1 gb:BC002444.1 gb:AF134159.2 gb:NM_007176.1 NM_007176 chromosome 14 open reading frame 1 C14orf1 11161 NM_007176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030133 // transport vesicle // inferred from direct assay 202564_x_at NM_001667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001667.1 /DEF=Homo sapiens ADP-ribosylation factor-like 2 (ARL2), mRNA. /FEA=mRNA /GEN=ARL2 /PROD=ADP-ribosylation factor-like 2 /DB_XREF=gi:4502228 /UG=Hs.154162 ADP-ribosylation factor-like 2 /FL=gb:BC002530.1 gb:L13687.1 gb:NM_001667.1 NM_001667 ADP-ribosylation factor-like 2 ARL2 402 NM_001199745 /// NM_001667 0006184 // GTP catabolic process // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007021 // tubulin complex assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0031113 // regulation of microtubule polymerization // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from mutant phenotype /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 202565_s_at NM_003174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003174.2 /DEF=Homo sapiens supervillin (SVIL), transcript variant 1, mRNA. /FEA=mRNA /GEN=SVIL /PROD=supervillin, isoform 1 /DB_XREF=gi:11496980 /UG=Hs.154567 supervillin /FL=gb:NM_003174.2 gb:AF051850.1 gb:AF051851.1 NM_003174 supervillin SVIL 6840 NM_003174 /// NM_021738 /// XM_005252564 /// XM_005252565 /// XM_005252566 /// XM_005252567 /// XM_005252568 /// XM_005252569 /// XM_005252570 /// XM_005252571 /// XM_005252572 /// XM_005252573 /// XM_006717492 /// XM_006717493 /// XM_006717494 /// XM_006717495 /// XM_006717496 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0071437 // invadopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 202566_s_at AF051851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051851.1 /DEF=Homo sapiens supervillin mRNA, complete cds. /FEA=mRNA /PROD=supervillin /DB_XREF=gi:2961251 /UG=Hs.154567 supervillin /FL=gb:NM_003174.2 gb:AF051850.1 gb:AF051851.1 AF051851 supervillin SVIL 6840 NM_003174 /// NM_021738 /// XM_005252564 /// XM_005252565 /// XM_005252566 /// XM_005252567 /// XM_005252568 /// XM_005252569 /// XM_005252570 /// XM_005252571 /// XM_005252572 /// XM_005252573 /// XM_006717492 /// XM_006717493 /// XM_006717494 /// XM_006717495 /// XM_006717496 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0071437 // invadopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 202567_at NM_004175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004175.1 /DEF=Homo sapiens small nuclear ribonucleoprotein D3 polypeptide (18kD) (SNRPD3), mRNA. /FEA=mRNA /GEN=SNRPD3 /PROD=small nuclear ribonucleoprotein D3 polypeptide(18kD) /DB_XREF=gi:4759159 /UG=Hs.1575 small nuclear ribonucleoprotein D3 polypeptide (18kD) /FL=gb:BC000457.1 gb:BC003150.1 gb:NM_004175.1 gb:U15009.1 NM_004175 small nuclear ribonucleoprotein D3 polypeptide 18kDa SNRPD3 6634 NM_001278656 /// NM_004175 /// NR_103819 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071208 // histone pre-mRNA DCP binding // inferred from sequence or structural similarity 202568_s_at AI745639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI745639 /FEA=EST /DB_XREF=gi:5113927 /DB_XREF=est:tr24b01.x1 /CLONE=IMAGE:2219209 /UG=Hs.172766 MAPmicrotubule affinity-regulating kinase 3 /FL=gb:M80359.1 gb:NM_002376.1 AI745639 MAP/microtubule affinity-regulating kinase 3 MARK3 4140 NM_001128918 /// NM_001128919 /// NM_001128920 /// NM_001128921 /// NM_002376 /// XM_005267641 /// XM_005267642 /// XM_005267643 /// XM_006720146 /// XM_006720147 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202569_s_at NM_002376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002376.1 /DEF=Homo sapiens MAPmicrotubule affinity-regulating kinase 3 (MARK3), mRNA. /FEA=mRNA /GEN=MARK3 /PROD=MAPmicrotubule affinity-regulating kinase 3 /DB_XREF=gi:4505102 /UG=Hs.172766 MAPmicrotubule affinity-regulating kinase 3 /FL=gb:M80359.1 gb:NM_002376.1 NM_002376 MAP/microtubule affinity-regulating kinase 3 MARK3 4140 NM_001128918 /// NM_001128919 /// NM_001128920 /// NM_001128921 /// NM_002376 /// XM_005267641 /// XM_005267642 /// XM_005267643 /// XM_006720146 /// XM_006720147 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202570_s_at BF346592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF346592 /FEA=EST /DB_XREF=gi:11294104 /DB_XREF=est:602020234F1 /CLONE=IMAGE:4155609 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1 BF346592 discs, large (Drosophila) homolog-associated protein 4 DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202571_s_at BE550798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE550798 /FEA=EST /DB_XREF=gi:9792490 /DB_XREF=est:7b59b04.x1 /CLONE=IMAGE:3232495 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1 BE550798 discs, large (Drosophila) homolog-associated protein 4 DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202572_s_at NM_014902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014902.1 /DEF=Homo sapiens KIAA0964 protein (KIAA0964), mRNA. /FEA=mRNA /GEN=KIAA0964 /PROD=KIAA0964 protein /DB_XREF=gi:7662411 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1 NM_014902 discs, large (Drosophila) homolog-associated protein 4 DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202573_at AL530441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL530441 /FEA=EST /DB_XREF=gi:12793934 /DB_XREF=est:AL530441 /CLONE=CS0DD007YK14 (3 prime) /UG=Hs.181390 casein kinase 1, gamma 2 /FL=gb:NM_001319.2 gb:U89896.1 AL530441 casein kinase 1, gamma 2 CSNK1G2 1455 NM_001319 /// XM_005259498 /// XM_005259499 /// XM_005259500 /// XM_005259501 /// XM_005259502 /// XR_430129 0006468 // protein phosphorylation // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202574_s_at NM_001319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001319.2 /DEF=Homo sapiens casein kinase 1, gamma 2 (CSNK1G2), mRNA. /FEA=mRNA /GEN=CSNK1G2 /PROD=casein kinase 1, gamma 2 /DB_XREF=gi:11079647 /UG=Hs.181390 casein kinase 1, gamma 2 /FL=gb:NM_001319.2 gb:U89896.1 NM_001319 casein kinase 1, gamma 2 CSNK1G2 1455 NM_001319 /// XM_005259498 /// XM_005259499 /// XM_005259500 /// XM_005259501 /// XM_005259502 /// XR_430129 0006468 // protein phosphorylation // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202575_at NM_001878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001878.2 /DEF=Homo sapiens cellular retinoic acid-binding protein 2 (CRABP2), mRNA. /FEA=mRNA /GEN=CRABP2 /PROD=cellular retinoic acid-binding protein 2 /DB_XREF=gi:6382069 /UG=Hs.183650 cellular retinoic acid-binding protein 2 /FL=gb:BC001109.1 gb:M68867.1 gb:NM_001878.2 NM_001878 cellular retinoic acid binding protein 2 CRABP2 1382 NM_001199723 /// NM_001878 /// XM_006711169 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001972 // retinoic acid binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 202576_s_at AL553254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL553254 /FEA=EST /DB_XREF=gi:12892919 /DB_XREF=est:AL553254 /CLONE=CS0DI073YF07 (3 prime) /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1 AL553254 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B DDX19A /// DDX19B 11269 /// 55308 NM_001014449 /// NM_001014451 /// NM_001257172 /// NM_001257173 /// NM_001257174 /// NM_001257175 /// NM_007242 /// NM_018332 /// XM_005256030 /// XM_006721126 /// XM_006721127 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202577_s_at BC005162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005162.1 /DEF=Homo sapiens, hypothetical protein FLJ11126, clone MGC:4651, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ11126 /DB_XREF=gi:13477370 /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1 BC005162 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A DDX19A 55308 NM_018332 /// XM_005256030 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202578_s_at NM_018332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018332.1 /DEF=Homo sapiens hypothetical protein FLJ11126 (FLJ11126), mRNA. /FEA=mRNA /GEN=FLJ11126 /PROD=hypothetical protein FLJ11126 /DB_XREF=gi:8922885 /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1 NM_018332 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A DDX19A 55308 NM_018332 /// XM_005256030 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202579_x_at NM_006353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006353.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 17-like 3 (HMG17L3), mRNA. /FEA=mRNA /GEN=HMG17L3 /PROD=high-mobility group (nonhistone chromosomal)protein 17-like 3 /DB_XREF=gi:10835239 /UG=Hs.236774 high-mobility group (nonhistone chromosomal) protein 17-like 3 /FL=gb:NM_006353.1 gb:U90549.1 NM_006353 high mobility group nucleosomal binding domain 4 HMGN4 10473 NM_006353 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 202580_x_at NM_021953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021953.1 /DEF=Homo sapiens forkhead box M1 (FOXM1), mRNA. /FEA=mRNA /GEN=FOXM1 /PROD=forkhead box M1 /DB_XREF=gi:11386144 /UG=Hs.239 forkhead box M1 /FL=gb:NM_021953.1 gb:U83113.1 gb:L16783.1 NM_021953 forkhead box M1 FOXM1 2305 NM_001243088 /// NM_001243089 /// NM_021953 /// NM_202002 /// NM_202003 /// XM_005253676 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // traceable author statement /// 0001570 // vasculogenesis // not recorded /// 0001889 // liver development // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007049 // cell cycle // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046578 // regulation of Ras protein signal transduction // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051726 // regulation of cell cycle // traceable author statement /// 0071156 // regulation of cell cycle arrest // inferred from mutant phenotype /// 0090344 // negative regulation of cell aging // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2000781 // positive regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202581_at NM_005346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005346.2 /DEF=Homo sapiens heat shock 70kD protein 1B (HSPA1B), mRNA. /FEA=mRNA /GEN=HSPA1B /PROD=heat shock 70kD protein 1B /DB_XREF=gi:5579470 /UG=Hs.274402 heat shock 70kD protein 1B /FL=gb:NM_005346.2 NM_005346 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 202582_s_at AF306510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF306510.1 /DEF=Homo sapiens RANBPM mRNA, complete cds. /FEA=mRNA /PROD=RANBPM /DB_XREF=gi:13194575 /UG=Hs.279886 RAN binding protein 9 /FL=gb:AF306510.1 gb:AB008515.1 gb:NM_005493.1 AF306510 RAN binding protein 9 RANBP9 10048 NM_005493 /// XM_006714945 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 202583_s_at NM_005493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005493.1 /DEF=Homo sapiens RAN binding protein 9 (RANBP9), mRNA. /FEA=mRNA /GEN=RANBP9 /PROD=RAN binding protein 9 /DB_XREF=gi:4885570 /UG=Hs.279886 RAN binding protein 9 /FL=gb:AF306510.1 gb:AB008515.1 gb:NM_005493.1 NM_005493 RAN binding protein 9 RANBP9 10048 NM_005493 /// XM_006714945 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 202584_at AW291398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW291398 /FEA=EST /DB_XREF=gi:6698118 /DB_XREF=est:UI-H-BI2-aga-d-06-0-UI.s1 /CLONE=IMAGE:2723746 /UG=Hs.3187 nuclear transcription factor, X-box binding 1 /FL=gb:NM_002504.1 gb:U15306.1 AW291398 nuclear transcription factor, X-box binding 1 NFX1 4799 NM_002504 /// NM_147133 /// NM_147134 /// XM_005251473 /// XM_005251474 /// XM_005251475 /// XM_006716776 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202585_s_at NM_002504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002504.1 /DEF=Homo sapiens nuclear transcription factor, X-box binding 1 (NFX1), mRNA. /FEA=mRNA /GEN=NFX1 /PROD=nuclear transcription factor, X-box binding 1 /DB_XREF=gi:4505386 /UG=Hs.3187 nuclear transcription factor, X-box binding 1 /FL=gb:NM_002504.1 gb:U15306.1 NM_002504 nuclear transcription factor, X-box binding 1 NFX1 4799 NM_002504 /// NM_147133 /// NM_147134 /// XM_005251473 /// XM_005251474 /// XM_005251475 /// XM_006716776 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202586_at AA772747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA772747 /FEA=EST /DB_XREF=gi:2824530 /DB_XREF=est:ai54b03.s1 /CLONE=1360781 /UG=Hs.71618 polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) /FL=gb:U37690.1 gb:NM_021128.1 AA772747 polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa POLR2L 5441 NM_021128 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0008270 // zinc ion binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 202587_s_at BC001116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001116.1 /DEF=Homo sapiens, adenylate kinase 1, clone MGC:1808, mRNA, complete cds. /FEA=mRNA /PROD=adenylate kinase 1 /DB_XREF=gi:12654562 /UG=Hs.76240 adenylate kinase 1 /FL=gb:BC001116.1 gb:NM_000476.1 gb:AB021871.1 BC001116 adenylate kinase 1 AK1 203 NM_000476 /// XM_005251786 /// XM_005251788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0001520 // outer dense fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 202588_at NM_000476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000476.1 /DEF=Homo sapiens adenylate kinase 1 (AK1), mRNA. /FEA=mRNA /GEN=AK1 /PROD=adenylate kinase 1 /DB_XREF=gi:4502010 /UG=Hs.76240 adenylate kinase 1 /FL=gb:BC001116.1 gb:NM_000476.1 gb:AB021871.1 NM_000476 adenylate kinase 1 AK1 203 NM_000476 /// XM_005251786 /// XM_005251788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0001520 // outer dense fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 202589_at NM_001071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001071.1 /DEF=Homo sapiens thymidylate synthetase (TYMS), mRNA. /FEA=mRNA /GEN=TYMS /PROD=thymidylate synthetase /DB_XREF=gi:4507750 /UG=Hs.82962 thymidylate synthetase /FL=gb:BC002567.1 gb:NM_001071.1 NM_001071 thymidylate synthetase TYMS 7298 NM_001071 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006231 // dTMP biosynthetic process // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019088 // immortalization of host cell by virus // inferred from electronic annotation /// 0019860 // uracil metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046078 // dUMP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004799 // thymidylate synthase activity // traceable author statement /// 0005542 // folic acid binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 202590_s_at AL574319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574319 /FEA=EST /DB_XREF=gi:12934412 /DB_XREF=est:AL574319 /CLONE=CS0DI057YO23 (3 prime) /UG=Hs.92261 pyruvate dehydrogenase kinase, isoenzyme 2 /FL=gb:L42451.1 gb:NM_002611.1 AL574319 pyruvate dehydrogenase kinase, isozyme 2 PDK2 5164 NM_001199898 /// NM_001199899 /// NM_001199900 /// NM_002611 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006111 // regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010565 // regulation of cellular ketone metabolic process // inferred from sequence or structural similarity /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031670 // cellular response to nutrient // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202591_s_at NM_003143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003143.1 /DEF=Homo sapiens single-stranded DNA-binding protein (SSBP), mRNA. /FEA=mRNA /GEN=SSBP /PROD=single-stranded DNA-binding protein /DB_XREF=gi:4507230 /UG=Hs.923 single-stranded DNA-binding protein /FL=gb:M94556.1 gb:NM_003143.1 NM_003143 single-stranded DNA binding protein 1, mitochondrial SSBP1 6742 NM_001256510 /// NM_001256511 /// NM_001256512 /// NM_001256513 /// NM_003143 /// NR_046269 /// XM_005250048 /// XM_005250049 /// XM_005250050 /// XM_005250051 0006260 // DNA replication // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202592_at NM_001487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001487.1 /DEF=Homo sapiens GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 (GCN5L1), mRNA. /FEA=mRNA /GEN=GCN5L1 /PROD=GCN5 (general control of amino-acid synthesis,yeast, homolog)-like 1 /DB_XREF=gi:4503954 /UG=Hs.94672 GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 /FL=gb:D64007.1 gb:NM_001487.1 NM_001487 biogenesis of lysosomal organelles complex-1, subunit 1 BLOC1S1 2647 NM_001487 /// NR_037655 /// NR_037656 /// NR_037657 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0018394 // peptidyl-lysine acetylation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032438 // melanosome organization // non-traceable author statement /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0060155 // platelet dense granule organization // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202593_s_at NM_016641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016641.1 /DEF=Homo sapiens membrane interacting protein of RGS16 (MIR16), mRNA. /FEA=mRNA /GEN=MIR16 /PROD=membrane interacting protein of RGS16 /DB_XREF=gi:7706616 /UG=Hs.107014 membrane interacting protein of RGS16 /FL=gb:AF212862.1 gb:NM_016641.1 NM_016641 glycerophosphodiester phosphodiesterase 1 GDE1 51573 NM_016641 /// XM_005255355 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047395 // glycerophosphoinositol glycerophosphodiesterase activity // inferred from electronic annotation 202594_at NM_015344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015344.1 /DEF=Homo sapiens MY047 protein (MY047), mRNA. /FEA=mRNA /GEN=MY047 /PROD=MY047 protein /DB_XREF=gi:7662509 /UG=Hs.11000 leptin receptor overlapping transcript-like 1 /FL=gb:BC000642.1 gb:AF063605.1 gb:AF161461.1 gb:NM_015344.1 NM_015344 leptin receptor overlapping transcript-like 1 LEPROTL1 23484 NM_001128208 /// NM_015344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202595_s_at AF161461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF161461.1 /DEF=Homo sapiens HSPC112 mRNA, complete cds. /FEA=mRNA /PROD=HSPC112 /DB_XREF=gi:6841445 /UG=Hs.11000 leptin receptor overlapping transcript-like 1 /FL=gb:BC000642.1 gb:AF063605.1 gb:AF161461.1 gb:NM_015344.1 AF161461 leptin receptor overlapping transcript-like 1 LEPROTL1 23484 NM_001128208 /// NM_015344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202596_at BC000436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000436.1 /DEF=Homo sapiens, endosulfine alpha, clone MGC:8394, mRNA, complete cds. /FEA=mRNA /PROD=endosulfine alpha /DB_XREF=gi:12653334 /UG=Hs.111680 endosulfine alpha /FL=gb:BC000436.1 gb:BC004461.1 gb:NM_004436.1 gb:AF157509.1 BC000436 endosulfine alpha ENSA 2029 NM_004436 /// NM_207042 /// NM_207043 /// NM_207044 /// NM_207045 /// NM_207046 /// NM_207047 /// NM_207168 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 202597_at AU144284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144284 /FEA=EST /DB_XREF=gi:11005805 /DB_XREF=est:AU144284 /CLONE=HEMBA1001439 /UG=Hs.11801 interferon regulatory factor 6 /FL=gb:AF027292.1 gb:NM_006147.1 AU144284 interferon regulatory factor 6 IRF6 3664 NM_001206696 /// NM_006147 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060644 // mammary gland epithelial cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202598_at NM_005979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005979.1 /DEF=Homo sapiens S100 calcium-binding protein A13 (S100A13), mRNA. /FEA=mRNA /GEN=S100A13 /PROD=S100 calcium-binding protein A13 /DB_XREF=gi:5174658 /UG=Hs.14331 S100 calcium-binding protein A13 /FL=gb:BC000632.1 gb:NM_005979.1 NM_005979 S100 calcium binding protein A13 S100A13 6284 NM_001024210 /// NM_001024211 /// NM_001024212 /// NM_001024213 /// NM_005979 /// XM_005245434 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043303 // mast cell degranulation // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from mutant phenotype /// 0050703 // interleukin-1 alpha secretion // inferred from direct assay /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0042629 // mast cell granule // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 202599_s_at NM_003489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003489.1 /DEF=Homo sapiens nuclear receptor interacting protein 1 (NRIP1), mRNA. /FEA=mRNA /GEN=NRIP1 /PROD=receptor interacting protein 140 /DB_XREF=gi:4505454 /UG=Hs.155017 nuclear receptor interacting protein 1 /FL=gb:NM_003489.1 NM_003489 nuclear receptor interacting protein 1 NRIP1 8204 NM_003489 /// XM_005261063 /// XM_005261065 /// XM_005261066 /// XM_006724054 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030728 // ovulation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202600_s_at AI824012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI824012 /FEA=EST /DB_XREF=gi:5444683 /DB_XREF=est:wj29e06.x1 /CLONE=IMAGE:2404258 /UG=Hs.155017 nuclear receptor interacting protein 1 /FL=gb:NM_003489.1 AI824012 nuclear receptor interacting protein 1 NRIP1 8204 NM_003489 /// XM_005261063 /// XM_005261065 /// XM_005261066 /// XM_006724054 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030728 // ovulation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202601_s_at AI373539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI373539 /FEA=EST /DB_XREF=gi:4153405 /DB_XREF=est:qz46h02.x1 /CLONE=IMAGE:2029971 /UG=Hs.171595 HIV TAT specific factor 1 /FL=gb:U76992.1 gb:NM_014500.1 AI373539 HIV-1 Tat specific factor 1 HTATSF1 27336 NM_001163280 /// NM_014500 /// XM_005262404 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202602_s_at NM_014500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014500.1 /DEF=Homo sapiens HIV TAT specific factor 1 (HTATSF1), mRNA. /FEA=mRNA /GEN=HTATSF1 /PROD=HIV TAT specific factor 1 /DB_XREF=gi:7657636 /UG=Hs.171595 HIV TAT specific factor 1 /FL=gb:U76992.1 gb:NM_014500.1 NM_014500 HIV-1 Tat specific factor 1 HTATSF1 27336 NM_001163280 /// NM_014500 /// XM_005262404 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202603_at N51370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N51370 /FEA=EST /DB_XREF=gi:1192536 /DB_XREF=est:yz16d01.s1 /CLONE=IMAGE:283201 /UG=Hs.172028 a disintegrin and metalloproteinase domain 10 /FL=gb:AF009615.1 gb:NM_001110.1 N51370 ADAM metallopeptidase domain 10 ADAM10 102 NM_001110 /// XM_005254117 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051089 // constitutive protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay /// 0097197 // tetraspanin-enriched microdomain // inferred from direct assay 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005102 // receptor binding // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202604_x_at NM_001110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001110.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 10 (ADAM10), mRNA. /FEA=mRNA /GEN=ADAM10 /PROD=a disintegrin and metalloprotease domain 10 /DB_XREF=gi:4557250 /UG=Hs.172028 a disintegrin and metalloproteinase domain 10 /FL=gb:AF009615.1 gb:NM_001110.1 NM_001110 ADAM metallopeptidase domain 10 ADAM10 102 NM_001110 /// XM_005254117 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051089 // constitutive protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay /// 0097197 // tetraspanin-enriched microdomain // inferred from direct assay 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005102 // receptor binding // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202605_at NM_000181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000181.1 /DEF=Homo sapiens glucuronidase, beta (GUSB), mRNA. /FEA=mRNA /GEN=GUSB /PROD=glucuronidase, beta /DB_XREF=gi:4504222 /UG=Hs.183868 glucuronidase, beta /FL=gb:M15182.1 gb:NM_000181.1 NM_000181 glucuronidase, beta GUSB 2990 NM_000181 /// NM_001284290 /// NM_001293104 /// NM_001293105 /// NR_120531 /// XM_005250297 /// XR_242233 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004566 // beta-glucuronidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 202606_s_at NM_012290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012290.1 /DEF=Homo sapiens tousled-like kinase 1 (TLK1), mRNA. /FEA=mRNA /GEN=TLK1 /PROD=tousled-like kinase 1 /DB_XREF=gi:6912719 /UG=Hs.18895 tousled-like kinase 1 /FL=gb:AB004885.1 gb:NM_012290.1 gb:AF246219.1 NM_012290 tousled-like kinase 1 TLK1 9874 NM_001136554 /// NM_001136555 /// NM_012290 /// XM_005246981 /// XM_006712883 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202607_at AL526632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL526632 /FEA=EST /DB_XREF=gi:12790125 /DB_XREF=est:AL526632 /CLONE=CS0DC020YC21 (3 prime) /UG=Hs.20894 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 /FL=gb:U36600.1 gb:NM_001543.1 gb:U17970.1 gb:U18918.1 AL526632 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 NDST1 3340 NM_001543 /// XM_005268433 /// XM_005268434 /// XM_005268435 /// XM_005268436 /// XM_005268437 /// XM_005268438 /// XM_005268439 /// XM_005268440 /// XM_005268441 /// XM_005268442 /// XM_006714782 /// XM_006714783 /// XR_245854 0000165 // MAPK cascade // inferred from electronic annotation /// 0000271 // polysaccharide biosynthetic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006477 // protein sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 202608_s_at NM_001543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001543.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 (NDST1), mRNA. /FEA=mRNA /GEN=NDST1 /PROD=N-deacetylaseN-sulfotransferase (heparanglucosaminyl) 1 /DB_XREF=gi:4505350 /UG=Hs.20894 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 /FL=gb:U36600.1 gb:NM_001543.1 gb:U17970.1 gb:U18918.1 NM_001543 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 NDST1 3340 NM_001543 /// XM_005268433 /// XM_005268434 /// XM_005268435 /// XM_005268436 /// XM_005268437 /// XM_005268438 /// XM_005268439 /// XM_005268440 /// XM_005268441 /// XM_005268442 /// XM_006714782 /// XM_006714783 /// XR_245854 0000165 // MAPK cascade // inferred from electronic annotation /// 0000271 // polysaccharide biosynthetic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006477 // protein sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 202609_at NM_004447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004447.1 /DEF=Homo sapiens epidermal growth factor receptor pathway substrate 8 (EPS8), mRNA. /FEA=mRNA /GEN=EPS8 /PROD=epidermal growth factor receptor pathwaysubstrate 8 /DB_XREF=gi:4758295 /UG=Hs.2132 epidermal growth factor receptor pathway substrate 8 /FL=gb:NM_004447.1 gb:U12535.1 NM_004447 epidermal growth factor receptor pathway substrate 8 EPS8 2059 NM_004447 /// XM_005253339 /// XM_005253340 /// XM_006719057 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010458 // exit from mitosis // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030832 // regulation of actin filament length // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0036336 // dendritic cell migration // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0070358 // actin polymerization-dependent cell motility // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity 202610_s_at AF135802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF135802.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein complex component TRAP170 mRNA, complete cds. /FEA=mRNA /PROD=thyroid hormone receptor-associated proteincomplex component TRAP170 /DB_XREF=gi:4580325 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1 AF135802 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202611_s_at AI971089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI971089 /FEA=EST /DB_XREF=gi:5767915 /DB_XREF=est:wr23g11.x1 /CLONE=IMAGE:2488580 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1 AI971089 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202612_s_at NM_004229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004229.1 /DEF=Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) (CRSP2), mRNA. /FEA=mRNA /GEN=CRSP2 /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 2 (150kD) /DB_XREF=gi:4758101 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1 NM_004229 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202613_at NM_001905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001905.1 /DEF=Homo sapiens CTP synthase (CTPS), mRNA. /FEA=mRNA /GEN=CTPS /PROD=CTP synthase /DB_XREF=gi:4503132 /UG=Hs.251871 CTP synthase /FL=gb:NM_001905.1 NM_001905 CTP synthase 1 CTPS1 1503 NM_001905 /// XM_005270536 /// XM_006710390 /// XM_006710391 /// XR_426589 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044210 // 'de novo' CTP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003883 // CTP synthase activity // not recorded /// 0003883 // CTP synthase activity // inferred from direct assay /// 0003883 // CTP synthase activity // inferred from genetic interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202614_at NM_006345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006345.2 /DEF=Homo sapiens chromosome 4 open reading frame 1 (C4ORF1), mRNA. /FEA=mRNA /GEN=C4ORF1 /PROD=chromosome 4 open reading frame 1 /DB_XREF=gi:7656945 /UG=Hs.270956 chromosome 4 open reading frame 1 /FL=gb:AF006621.2 gb:NM_006345.2 NM_006345 solute carrier family 30 (zinc transporter), member 9 SLC30A9 10463 NM_006345 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation 202615_at BF222895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222895 /FEA=EST /DB_XREF=gi:11130072 /DB_XREF=est:7q24f10.x1 /CLONE=IMAGE:3699235 /UG=Hs.296261 guanine nucleotide binding protein (G protein), q polypeptide /FL=gb:U43083.1 gb:AF329284.1 gb:AF011496.1 gb:NM_002072.1 BF222895 guanine nucleotide binding protein (G protein), q polypeptide GNAQ 2776 NM_002072 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007215 // glutamate receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016322 // neuron remodeling // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 202616_s_at AI631140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI631140 /FEA=EST /DB_XREF=gi:4682470 /DB_XREF=est:ts93b07.x1 /CLONE=IMAGE:2238805 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1 AI631140 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202617_s_at NM_004992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004992.2 /DEF=Homo sapiens methyl CpG binding protein 2 (Rett syndrome) (MECP2), mRNA. /FEA=mRNA /GEN=MECP2 /PROD=methyl CpG binding protein 2 /DB_XREF=gi:7710148 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1 NM_004992 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202618_s_at L37298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L37298.1 /DEF=Homo sapiens methyl-CpG-binding protein (MeCP-2) mRNA, complete cds. /FEA=mRNA /GEN=MeCP-2 /PROD=methyl-CpG-binding protein /DB_XREF=gi:972764 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1 L37298 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202619_s_at AI754404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI754404 /FEA=EST /DB_XREF=gi:5132668 /DB_XREF=est:cr24g06.x1 /CLONE=HBMSC_cr24g06 /UG=Hs.41270 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 /FL=gb:U84573.1 gb:NM_000935.1 AI754404 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 PLOD2 5352 NM_000935 /// NM_182943 /// XM_005247535 /// XM_005247536 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 202620_s_at NM_000935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000935.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 (PLOD2), mRNA. /FEA=mRNA /GEN=PLOD2 /PROD=procollagen-lysine, 2-oxoglutarate 5-dioxygenase(lysine hydroxylase) 2 /DB_XREF=gi:4505888 /UG=Hs.41270 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 /FL=gb:U84573.1 gb:NM_000935.1 NM_000935 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 PLOD2 5352 NM_000935 /// NM_182943 /// XM_005247535 /// XM_005247536 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 202621_at NM_001571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001571.1 /DEF=Homo sapiens interferon regulatory factor 3 (IRF3), mRNA. /FEA=mRNA /GEN=IRF3 /PROD=interferon regulatory factor 3 /DB_XREF=gi:4504724 /UG=Hs.75254 interferon regulatory factor 3 /FL=gb:NM_001571.1 NM_001571 interferon regulatory factor 3 IRF3 3661 NM_001197122 /// NM_001197123 /// NM_001197124 /// NM_001197125 /// NM_001197126 /// NM_001197127 /// NM_001197128 /// NM_001571 /// NR_045568 /// XM_006723197 /// XM_006723198 /// XM_006723199 /// XM_006723200 /// XM_006723201 /// XM_006723202 /// XR_430199 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0039530 // MDA-5 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0045358 // negative regulation of interferon-beta biosynthetic process // inferred from electronic annotation /// 0050689 // negative regulation of defense response to virus by host // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation /// 0071359 // cellular response to dsRNA // inferred from electronic annotation /// 0071888 // macrophage apoptotic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202622_s_at NM_002973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002973.1 /DEF=Homo sapiens spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2) (SCA2), mRNA. /FEA=mRNA /GEN=SCA2 /PROD=ataxin 2 /DB_XREF=gi:4506794 /UG=Hs.76253 spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2) /FL=gb:U70323.1 gb:NM_002973.1 NM_002973 ataxin 2 ATXN2 6311 NM_002973 0002091 // negative regulation of receptor internalization // inferred from mutant phenotype /// 0006417 // regulation of translation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0034063 // stress granule assembly // inferred from mutant phenotype /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0050658 // RNA transport // non-traceable author statement /// 0050905 // neuromuscular process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005844 // polysome // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202623_at NM_018453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018453.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM036 (BM036), mRNA. /FEA=mRNA /GEN=BM036 /PROD=uncharacterized bone marrow protein BM036 /DB_XREF=gi:8922092 /UG=Hs.7731 uncharacterized bone marrow protein BM036 /FL=gb:BC001245.1 gb:AF217512.1 gb:NM_018453.1 NM_018453 E2F-associated phosphoprotein EAPP 55837 NM_018453 /// XM_005267858 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 202624_s_at NM_012295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012295.1 /DEF=Homo sapiens calcineurin binding protein 1 (KIAA0330), mRNA. /FEA=mRNA /GEN=KIAA0330 /PROD=calcineurin binding protein 1 /DB_XREF=gi:6912457 /UG=Hs.7840 calcineurin binding protein 1 /FL=gb:AF072441.1 gb:NM_012295.1 NM_012295 calcineurin binding protein 1 CABIN1 23523 NM_001199281 /// NM_001201429 /// NM_012295 /// XM_005261415 /// XM_005261416 /// XM_005261417 /// XM_005261419 /// XM_005261420 /// XM_006724179 /// XM_006724180 /// XM_006724181 /// XM_006724182 /// XM_006724183 /// XM_006724184 /// XR_430404 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202625_at AI356412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI356412 /FEA=EST /DB_XREF=gi:4108033 /DB_XREF=est:qz26h02.x1 /CLONE=IMAGE:2028051 /UG=Hs.80887 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog /FL=gb:NM_002350.1 AI356412 LYN proto-oncogene, Src family tyrosine kinase LYN 4067 NM_001111097 /// NM_002350 /// XM_005251233 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // traceable author statement /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // traceable author statement /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002576 // platelet degranulation // inferred from sequence or structural similarity /// 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from sequence or structural similarity /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred by curator /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045646 // regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070304 // positive regulation of stress-activated protein kinase signaling cascade // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070447 // positive regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0070667 // negative regulation of mast cell proliferation // inferred from sequence or structural similarity /// 0070668 // positive regulation of mast cell proliferation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090025 // regulation of monocyte chemotaxis // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034666 // integrin alpha2-beta1 complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202626_s_at NM_002350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002350.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN), mRNA. /FEA=mRNA /GEN=LYN /PROD=v-yes-1 Yamaguchi sarcoma viral related oncogenehomolog /DB_XREF=gi:4505054 /UG=Hs.80887 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog /FL=gb:NM_002350.1 NM_002350 LYN proto-oncogene, Src family tyrosine kinase LYN 4067 NM_001111097 /// NM_002350 /// XM_005251233 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // traceable author statement /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // traceable author statement /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002576 // platelet degranulation // inferred from sequence or structural similarity /// 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from sequence or structural similarity /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred by curator /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045646 // regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070304 // positive regulation of stress-activated protein kinase signaling cascade // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070447 // positive regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0070667 // negative regulation of mast cell proliferation // inferred from sequence or structural similarity /// 0070668 // positive regulation of mast cell proliferation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090025 // regulation of monocyte chemotaxis // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034666 // integrin alpha2-beta1 complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202627_s_at AL574210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574210 /FEA=EST /DB_XREF=gi:12934198 /DB_XREF=est:AL574210 /CLONE=CS0DI039YB02 (3 prime) /UG=Hs.82085 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 /FL=gb:NM_000602.1 gb:M16006.1 AL574210 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 SERPINE1 5054 NM_000602 /// NM_001165413 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from mutant phenotype /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from mutant phenotype /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035491 // positive regulation of leukotriene production involved in inflammatory response // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from genetic interaction /// 0050829 // defense response to Gram-negative bacterium // inferred from genetic interaction /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0061044 // negative regulation of vascular wound healing // inferred from genetic interaction /// 0061045 // negative regulation of wound healing // inferred by curator /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202628_s_at NM_000602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000602.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), mRNA. /FEA=mRNA /GEN=SERPINE1 /PROD=serine (or cysteine) proteinase inhibitor, cladeE (nexin, plasminogen activator inhibitor type 1), member1 /DB_XREF=gi:10835158 /UG=Hs.82085 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 /FL=gb:NM_000602.1 gb:M16006.1 NM_000602 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 SERPINE1 5054 NM_000602 /// NM_001165413 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from mutant phenotype /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from mutant phenotype /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035491 // positive regulation of leukotriene production involved in inflammatory response // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from genetic interaction /// 0050829 // defense response to Gram-negative bacterium // inferred from genetic interaction /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0061044 // negative regulation of vascular wound healing // inferred from genetic interaction /// 0061045 // negative regulation of wound healing // inferred by curator /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202629_at AV681579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV681579 /FEA=EST /DB_XREF=gi:10283442 /DB_XREF=est:AV681579 /CLONE=GKBAFE05 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1 AV681579 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202630_at AA046411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA046411 /FEA=EST /DB_XREF=gi:1526376 /DB_XREF=est:zf47b09.s1 /CLONE=IMAGE:380057 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1 AA046411 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202631_s_at NM_006380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006380.1 /DEF=Homo sapiens amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 (APPBP2), mRNA. /FEA=mRNA /GEN=APPBP2 /PROD=amyloid beta precursor protein (cytoplasmictail)-binding protein 2 /DB_XREF=gi:5453552 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1 NM_006380 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202632_at NM_001383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001383.1 /DEF=Homo sapiens diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1 (DPH2L1), mRNA. /FEA=mRNA /GEN=DPH2L1 /PROD=diptheria toxin resistance protein required fordiphthamide biosynthesis (Saccharomyces)-like 1 /DB_XREF=gi:4503360 /UG=Hs.84183 diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1 /FL=gb:BC003099.1 gb:AF321876.1 gb:U34880.1 gb:NM_001383.1 NM_001383 diphthamide biosynthesis 1 /// ovarian tumor suppressor candidate 2 DPH1 /// OVCA2 1801 /// 124641 NM_001383 /// NM_080822 0006412 // translation // traceable author statement /// 0008152 // metabolic process // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // non-traceable author statement 202633_at NM_007027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007027.1 /DEF=Homo sapiens topoisomerase (DNA) II binding protein (TOPBP1), mRNA. /FEA=mRNA /GEN=TOPBP1 /PROD=topoisomerase (DNA) II binding protein /DB_XREF=gi:5902137 /UG=Hs.91417 topoisomerase (DNA) II binding protein /FL=gb:AB019397.1 gb:NM_007027.1 NM_007027 topoisomerase (DNA) II binding protein 1 TOPBP1 11073 NM_007027 /// XM_005247076 0006259 // DNA metabolic process // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202634_at AL558030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL558030 /FEA=EST /DB_XREF=gi:12902161 /DB_XREF=est:AL558030 /CLONE=CS0DJ002YJ02 (5 prime) /UG=Hs.150675 polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) /FL=gb:BC000806.1 gb:NM_005034.1 AL558030 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa POLR2K 5440 NM_005034 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202635_s_at NM_005034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005034.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) (POLR2K), mRNA. /FEA=mRNA /GEN=POLR2K /PROD=polymerase (RNA) II (DNA directed) polypeptide K(7.0kD) /DB_XREF=gi:4826923 /UG=Hs.150675 polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) /FL=gb:BC000806.1 gb:NM_005034.1 NM_005034 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa POLR2K 5440 NM_005034 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202636_at NM_005667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005667.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp103 in mouse (ZFP103), mRNA. /FEA=mRNA /GEN=ZFP103 /PROD=zinc finger protein homologous to Zfp103 inmouse /DB_XREF=gi:5031824 /UG=Hs.155968 zinc finger protein homologous to Zfp103 in mouse /FL=gb:D76444.1 gb:NM_005667.1 NM_005667 ring finger protein 103 RNF103 7844 NM_001198951 /// NM_001198952 /// NM_005667 0007417 // central nervous system development // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202637_s_at AI608725 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI608725 /FEA=EST /DB_XREF=gi:4617892 /DB_XREF=est:tw90b01.x1 /CLONE=IMAGE:2266921 /UG=Hs.168383 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor /FL=gb:M24283.1 gb:J03132.1 gb:NM_000201.1 AI608725 intercellular adhesion molecule 1 ICAM1 3383 NM_000201 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001910 // regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from electronic annotation /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007569 // cell aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010477 // response to sulfur dioxide // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202638_s_at NM_000201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000201.1 /DEF=Homo sapiens intercellular adhesion molecule 1 (CD54), human rhinovirus receptor (ICAM1), mRNA. /FEA=mRNA /GEN=ICAM1 /PROD=intercellular adhesion molecule 1 precursor /DB_XREF=gi:4557877 /UG=Hs.168383 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor /FL=gb:M24283.1 gb:J03132.1 gb:NM_000201.1 NM_000201 intercellular adhesion molecule 1 ICAM1 3383 NM_000201 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001910 // regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from electronic annotation /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007569 // cell aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010477 // response to sulfur dioxide // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202639_s_at AI689052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI689052 /FEA=EST /DB_XREF=gi:4900346 /DB_XREF=est:tx81b08.x1 /CLONE=IMAGE:2275959 /UG=Hs.176657 RAN binding protein 3 /FL=gb:NM_003624.1 AI689052 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 202640_s_at NM_003624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003624.1 /DEF=Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-a, mRNA. /FEA=mRNA /GEN=RANBP3 /PROD=RAN binding protein 3, isoform RANBP3-a /DB_XREF=gi:4506408 /UG=Hs.176657 RAN binding protein 3 /FL=gb:NM_003624.1 NM_003624 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 202641_at NM_004311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004311.1 /DEF=Homo sapiens ADP-ribosylation factor-like 3 (ARL3), mRNA. /FEA=mRNA /GEN=ARL3 /PROD=ADP-ribosylation factor-like 3 /DB_XREF=gi:4757773 /UG=Hs.182215 ADP-ribosylation factor-like 3 /FL=gb:U07151.1 gb:NM_004311.1 NM_004311 ADP-ribosylation factor-like 3 ARL3 403 NM_004311 0000910 // cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0042461 // photoreceptor cell development // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202642_s_at NM_003496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003496.1 /DEF=Homo sapiens transformationtranscription domain-associated protein (TRRAP), mRNA. /FEA=mRNA /GEN=TRRAP /PROD=transformationtranscription domain-associatedprotein /DB_XREF=gi:4507690 /UG=Hs.203952 transformationtranscription domain-associated protein /FL=gb:AF076974.1 gb:NM_003496.1 NM_003496 transformation/transcription domain-associated protein TRRAP 8295 NM_001244580 /// NM_003496 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // non-traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000125 // PCAF complex // non-traceable author statement /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202643_s_at AI738896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738896 /FEA=EST /DB_XREF=gi:5100877 /DB_XREF=est:wi22g02.x1 /CLONE=IMAGE:2391026 /UG=Hs.211600 tumor necrosis factor, alpha-induced protein 3 /FL=gb:M59465.1 gb:NM_006290.1 AI738896 tumor necrosis factor, alpha-induced protein 3 TNFAIP3 7128 NM_001270507 /// NM_001270508 /// NM_006290 /// XM_005267119 /// XM_006715555 0001922 // B-1 B cell homeostasis // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // non-traceable author statement /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from direct assay /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // non-traceable author statement /// 0034148 // negative regulation of toll-like receptor 5 signaling pathway // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // non-traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // non-traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0061043 // regulation of vascular wound healing // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070429 // negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070433 // negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0072573 // tolerance induction to lipopolysaccharide // inferred from mutant phenotype /// 0090291 // negative regulation of osteoclast proliferation // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2000349 // negative regulation of CD40 signaling pathway // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202644_s_at NM_006290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006290.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 3 (TNFAIP3), mRNA. /FEA=mRNA /GEN=TNFAIP3 /PROD=tumor necrosis factor, alpha-induced protein 3 /DB_XREF=gi:5454131 /UG=Hs.211600 tumor necrosis factor, alpha-induced protein 3 /FL=gb:M59465.1 gb:NM_006290.1 NM_006290 tumor necrosis factor, alpha-induced protein 3 TNFAIP3 7128 NM_001270507 /// NM_001270508 /// NM_006290 /// XM_005267119 /// XM_006715555 0001922 // B-1 B cell homeostasis // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // non-traceable author statement /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from direct assay /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // non-traceable author statement /// 0034148 // negative regulation of toll-like receptor 5 signaling pathway // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // non-traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // non-traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0061043 // regulation of vascular wound healing // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070429 // negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070433 // negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0072573 // tolerance induction to lipopolysaccharide // inferred from mutant phenotype /// 0090291 // negative regulation of osteoclast proliferation // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2000349 // negative regulation of CD40 signaling pathway // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202645_s_at NM_000244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000244.1 /DEF=Homo sapiens multiple endocrine neoplasia I (MEN1), mRNA. /FEA=mRNA /GEN=MEN1 /PROD=multiple endocrine neoplasia I /DB_XREF=gi:4557744 /UG=Hs.24297 multiple endocrine neoplasia I /FL=gb:U93236.1 gb:NM_000244.1 NM_000244 multiple endocrine neoplasia I MEN1 4221 NM_000244 /// NM_130799 /// NM_130800 /// NM_130801 /// NM_130802 /// NM_130803 /// NM_130804 /// XM_005274001 /// XM_005274002 /// XM_005274003 /// XM_006718557 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from direct assay /// 0001503 // ossification // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from genetic interaction /// 0006281 // DNA repair // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0009790 // embryo development // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0031062 // positive regulation of histone methylation // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032925 // regulation of activin receptor signaling pathway // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from genetic interaction /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay 0000400 // four-way junction DNA binding // inferred from direct assay /// 0000403 // Y-form DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 202646_s_at AA167775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA167775 /FEA=EST /DB_XREF=gi:1744943 /DB_XREF=est:zq40g07.s1 /CLONE=IMAGE:632220 /UG=Hs.260523 neuroblastoma RAS viral (v-ras) oncogene homolog /FL=gb:BC005219.1 gb:NM_002524.2 AA167775 cold shock domain containing E1, RNA-binding CSDE1 7812 NM_001007553 /// NM_001130523 /// NM_001242891 /// NM_001242892 /// NM_001242893 /// NM_007158 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202647_s_at NM_002524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002524.2 /DEF=Homo sapiens neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS), mRNA. /FEA=mRNA /GEN=NRAS /PROD=neuroblastoma RAS viral (v-ras) oncogenehomolog /DB_XREF=gi:6006027 /UG=Hs.260523 neuroblastoma RAS viral (v-ras) oncogene homolog /FL=gb:BC005219.1 gb:NM_002524.2 NM_002524 neuroblastoma RAS viral (v-ras) oncogene homolog NRAS 4893 NM_002524 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 202648_at BC000023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000023.1 /DEF=Homo sapiens, ribosomal protein S19, clone MGC:1630, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S19 /DB_XREF=gi:12652562 /UG=Hs.298262 ribosomal protein S19 /FL=gb:BC000023.1 gb:M81757.1 gb:NM_001022.1 BC000023 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 202649_x_at NM_001022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001022.1 /DEF=Homo sapiens ribosomal protein S19 (RPS19), mRNA. /FEA=mRNA /GEN=RPS19 /PROD=ribosomal protein S19 /DB_XREF=gi:4506694 /UG=Hs.298262 ribosomal protein S19 /FL=gb:BC000023.1 gb:M81757.1 gb:NM_001022.1 NM_001022 ribosomal protein S19 RPS19 6223 NM_001022 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007000 // nucleolus organization // inferred from mutant phenotype /// 0009991 // response to extracellular stimulus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0051272 // positive regulation of cellular component movement // traceable author statement /// 0060265 // positive regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202650_s_at NM_014738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014738.1 /DEF=Homo sapiens KIAA0195 gene product (KIAA0195), mRNA. /FEA=mRNA /GEN=KIAA0195 /PROD=KIAA0195 gene product /DB_XREF=gi:7661985 /UG=Hs.301132 KIAA0195 gene product /FL=gb:D83779.1 gb:NM_014738.1 NM_014738 KIAA0195 /// microRNA 6785 KIAA0195 /// MIR6785 9772 /// 102466911 NM_014738 /// NR_106843 /// XM_005257863 /// XM_005257864 /// XM_005257865 /// XM_005257866 /// XM_005257867 /// XM_005257868 /// XM_006722200 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202651_at NM_014873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014873.1 /DEF=Homo sapiens KIAA0205 gene product (KIAA0205), mRNA. /FEA=mRNA /GEN=KIAA0205 /PROD=KIAA0205 gene product /DB_XREF=gi:7661995 /UG=Hs.3610 KIAA0205 gene product /FL=gb:D86960.1 gb:NM_014873.1 NM_014873 lysophosphatidylglycerol acyltransferase 1 LPGAT1 9926 NM_014873 /// XM_005273362 /// XM_005273363 /// XM_005273364 /// XM_006711695 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 202652_at NM_001164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001164.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), mRNA. /FEA=mRNA /GEN=APBB1 /PROD=amyloid beta (A4) precursor protein-binding,family B, member 1 (Fe65) /DB_XREF=gi:4502130 /UG=Hs.3763 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) /FL=gb:L77864.1 gb:NM_001164.1 NM_001164 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) APBB1 322 NM_001164 /// NM_001257319 /// NM_001257320 /// NM_001257321 /// NM_001257322 /// NM_001257323 /// NM_001257324 /// NM_001257325 /// NM_001257326 /// NM_145689 /// NR_047512 /// XM_006718209 /// XM_006718210 /// XM_006718211 /// XM_006718212 /// XM_006718213 /// XM_006718214 /// XM_006718215 /// XM_006718216 0001764 // neuron migration // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050760 // negative regulation of thymidylate synthase biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0001540 // beta-amyloid binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0042393 // histone binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from physical interaction 202653_s_at BC003404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003404.1 /DEF=Homo sapiens, hypothetical protein DKFZp586F1122 similar to axotrophin, clone IMAGE:3449089, mRNA, partial cds. /FEA=mRNA /PROD=hypothetical protein DKFZp586F1122 similar toaxotrophin /DB_XREF=gi:13097302 /UG=Hs.5306 hypothetical protein DKFZp586F1122 similar to axotrophin /FL=gb:NM_022826.1 BC003404 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase MARCH7 64844 NM_001282805 /// NM_001282806 /// NM_001282807 /// NM_022826 /// XM_005246773 /// XM_005246774 /// XR_427106 0006909 // phagocytosis // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202654_x_at NM_022826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022826.1 /DEF=Homo sapiens hypothetical protein DKFZp586F1122 similar to axotrophin (DKFZP586F1122), mRNA. /FEA=mRNA /GEN=DKFZP586F1122 /PROD=hypothetical protein DKFZp586F1122 similar toaxotrophin /DB_XREF=gi:12383065 /UG=Hs.5306 hypothetical protein DKFZp586F1122 similar to axotrophin /FL=gb:NM_022826.1 NM_022826 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase MARCH7 64844 NM_001282805 /// NM_001282806 /// NM_001282807 /// NM_022826 /// XM_005246773 /// XM_005246774 /// XR_427106 0006909 // phagocytosis // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202655_at NM_006010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006010.1 /DEF=Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA. /FEA=mRNA /GEN=ARMET /PROD=arginine-rich protein /DB_XREF=gi:5174392 /UG=Hs.75412 arginine-rich, mutated in early stage tumors /FL=gb:M83751.1 gb:NM_006010.1 NM_006010 mesencephalic astrocyte-derived neurotrophic factor MANF 7873 NM_006010 0002014 // vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202656_s_at BG107456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG107456 /FEA=EST /DB_XREF=gi:12601302 /DB_XREF=est:602277568F1 /CLONE=IMAGE:4365352 /UG=Hs.77293 KIAA0127 gene product /FL=gb:D50917.1 gb:NM_014755.1 BG107456 SERTA domain containing 2 SERTAD2 9792 NM_014755 /// XM_005264669 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202657_s_at NM_014755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014755.1 /DEF=Homo sapiens KIAA0127 gene product (KIAA0127), mRNA. /FEA=mRNA /GEN=KIAA0127 /PROD=KIAA0127 gene product /DB_XREF=gi:7661925 /UG=Hs.77293 KIAA0127 gene product /FL=gb:D50917.1 gb:NM_014755.1 NM_014755 SERTA domain containing 2 SERTAD2 9792 NM_014755 /// XM_005264669 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202658_at NM_003846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003846.1 /DEF=Homo sapiens peroxisomal biogenesis factor 11B (PEX11B), mRNA. /FEA=mRNA /GEN=PEX11B /PROD=peroxisomal biogenesis factor 11B /DB_XREF=gi:4505718 /UG=Hs.83023 peroxisomal biogenesis factor 11B /FL=gb:AF093670.1 gb:AB018080.1 gb:NM_003846.1 NM_003846 peroxisomal biogenesis factor 11 beta PEX11B 8799 NM_001184795 /// NM_003846 /// NR_073491 /// NR_073492 /// NR_073493 0007031 // peroxisome organization // inferred from direct assay /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0016559 // peroxisome fission // inferred from direct assay /// 0044375 // regulation of peroxisome size // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202659_at NM_002801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002801.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10), mRNA. /FEA=mRNA /GEN=PSMB10 /PROD=proteasome (prosome, macropain) subunit, betatype, 10 /DB_XREF=gi:4506190 /UG=Hs.9661 proteasome (prosome, macropain) subunit, beta type, 10 /FL=gb:NM_002801.1 NM_002801 proteasome (prosome, macropain) subunit, beta type, 10 PSMB10 5699 NM_002801 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202660_at AA834576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA834576 /FEA=EST /DB_XREF=gi:2908175 /DB_XREF=est:od63f10.s1 /CLONE=IMAGE:1372651 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1 AA834576 inositol 1,4,5-trisphosphate receptor, type 2 ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202661_at AI963873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI963873 /FEA=EST /DB_XREF=gi:5756586 /DB_XREF=est:wt86b08.x1 /CLONE=IMAGE:2514327 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1 AI963873 inositol 1,4,5-trisphosphate receptor, type 2 ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202662_s_at NM_002223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002223.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 2 (ITPR2), mRNA. /FEA=mRNA /GEN=ITPR2 /PROD=inositol 1,4,5-triphosphate receptor, type 2 /DB_XREF=gi:4504792 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1 NM_002223 inositol 1,4,5-trisphosphate receptor, type 2 ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202663_at AI005043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI005043 /FEA=EST /DB_XREF=gi:3214553 /DB_XREF=est:ou91c11.x1 /CLONE=IMAGE:1635188 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2 AI005043 WAS/WASL interacting protein family, member 1 WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202664_at AW058622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW058622 /FEA=EST /DB_XREF=gi:5934261 /DB_XREF=est:wy59c01.x1 /CLONE=IMAGE:2552832 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2 AW058622 WAS/WASL interacting protein family, member 1 WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202665_s_at NM_003387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003387.2 /DEF=Homo sapiens Wiskott-Aldrich syndrome protein interacting protein (WASPIP), mRNA. /FEA=mRNA /GEN=WASPIP /PROD=WASP-interacting protein /DB_XREF=gi:8400739 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2 NM_003387 WAS/WASL interacting protein family, member 1 WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202666_s_at NM_004301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004301.1 /DEF=Homo sapiens BAF53 (BAF53A), mRNA. /FEA=mRNA /GEN=BAF53A /PROD=BAF53a /DB_XREF=gi:4757717 /UG=Hs.274350 BAF53 /FL=gb:AL136608.1 gb:BC001391.1 gb:BC000949.2 gb:AF041474.1 gb:AB015907.1 gb:NM_004301.1 NM_004301 actin-like 6A ACTL6A 86 NM_004301 /// NM_177989 /// NM_178042 0003407 // neural retina development // inferred from expression pattern /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 202667_s_at NM_006979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006979.1 /DEF=Homo sapiens HLA class II region expressed gene KE4 (HKE4), mRNA. /FEA=mRNA /GEN=HKE4 /PROD=HLA class II region expressed gene KE4 /DB_XREF=gi:5901935 /UG=Hs.278721 HLA class II region expressed gene KE4 /FL=gb:D82060.1 gb:NM_006979.1 NM_006979 solute carrier family 39 (zinc transporter), member 7 SLC39A7 7922 NM_001077516 /// NM_001288777 /// NM_006979 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202668_at BF001670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001670 /FEA=EST /DB_XREF=gi:10701945 /DB_XREF=est:7g91e06.x1 /CLONE=IMAGE:3313858 /UG=Hs.30942 ephrin-B2 /FL=gb:U81262.1 gb:NM_004093.1 gb:L38734.1 gb:U16797.1 BF001670 ephrin-B2 EFNB2 1948 NM_004093 0001525 // angiogenesis // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010839 // negative regulation of keratinocyte proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from direct assay /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202669_s_at U16797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16797.1 /DEF=Human LERK-5 (EPLG5) mRNA, complete cds. /FEA=mRNA /GEN=EPLG5 /PROD=LERK-5 /DB_XREF=gi:902370 /UG=Hs.30942 ephrin-B2 /FL=gb:U81262.1 gb:NM_004093.1 gb:L38734.1 gb:U16797.1 U16797 ephrin-B2 EFNB2 1948 NM_004093 0001525 // angiogenesis // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010839 // negative regulation of keratinocyte proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from direct assay /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202670_at AI571419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI571419 /FEA=EST /DB_XREF=gi:4534793 /DB_XREF=est:tn45h10.x1 /CLONE=IMAGE:2170627 /UG=Hs.3446 mitogen-activated protein kinase kinase 1 /FL=gb:L05624.1 gb:NM_002755.1 AI571419 mitogen-activated protein kinase kinase 1 MAP2K1 5604 NM_002755 /// XM_005254541 /// XM_006720608 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003056 // regulation of vascular smooth muscle contraction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0034111 // negative regulation of homotypic cell-cell adhesion // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048313 // Golgi inheritance // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048870 // cell motility // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 0090398 // cellular senescence // inferred from mutant phenotype /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005816 // spindle pole body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004728 // receptor signaling protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay 202671_s_at NM_003681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003681.1 /DEF=Homo sapiens pyridoxal (pyridoxine, vitamin B6) kinase (PDXK), mRNA. /FEA=mRNA /GEN=PDXK /PROD=pyridoxal kinase /DB_XREF=gi:4505700 /UG=Hs.38041 pyridoxal (pyridoxine, vitamin B6) kinase /FL=gb:BC000123.1 gb:U89606.1 gb:NM_003681.1 NM_003681 pyridoxal (pyridoxine, vitamin B6) kinase PDXK 8566 NM_003681 /// NM_021941 /// XM_005261195 /// XM_005261196 /// XM_005261198 /// XM_005261199 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0009443 // pyridoxal 5'-phosphate salvage // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042816 // vitamin B6 metabolic process // inferred by curator /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0042823 // pyridoxal phosphate biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008478 // pyridoxal kinase activity // inferred from direct assay /// 0008478 // pyridoxal kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from direct assay /// 0031402 // sodium ion binding // inferred from direct assay /// 0031403 // lithium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202672_s_at NM_001674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001674.1 /DEF=Homo sapiens activating transcription factor 3 (ATF3), mRNA. /FEA=mRNA /GEN=ATF3 /PROD=activating transcription factor 3 long isoform /DB_XREF=gi:4502262 /UG=Hs.460 activating transcription factor 3 /FL=gb:L19871.1 gb:NM_001674.1 NM_001674 activating transcription factor 3 ATF3 467 NM_001030287 /// NM_001040619 /// NM_001206484 /// NM_001206485 /// NM_001206486 /// NM_001206488 /// NM_001674 /// NM_004024 /// XM_005273146 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202673_at NM_003859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003859.1 /DEF=Homo sapiens dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit (DPM1), mRNA. /FEA=mRNA /GEN=DPM1 /PROD=dolichyl-phosphate mannosyltransferasepolypeptide 1 /DB_XREF=gi:4503362 /UG=Hs.5085 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit /FL=gb:D86198.1 gb:NM_003859.1 NM_003859 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit DPM1 8813 NM_003859 /// XM_005260600 /// XM_005260601 /// XM_005260602 /// XR_244156 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019348 // dolichol metabolic process // inferred from direct assay /// 0019673 // GDP-mannose metabolic process // inferred from electronic annotation /// 0035268 // protein mannosylation // inferred from direct assay /// 0035269 // protein O-linked mannosylation // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0033185 // dolichol-phosphate-mannose synthase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // inferred from direct assay /// 0004582 // dolichyl-phosphate beta-D-mannosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043178 // alcohol binding // inferred from electronic annotation 202674_s_at NM_005358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005358.2 /DEF=Homo sapiens LIM domain only 7 (LMO7), mRNA. /FEA=mRNA /GEN=LMO7 /PROD=LIM domain only 7 isoform a /DB_XREF=gi:7369018 /UG=Hs.5978 LIM domain only 7 /FL=gb:AF144237.1 gb:NM_005358.2 NM_005358 LIM domain 7 LMO7 4008 NM_005358 /// NM_015842 /// NM_015843 /// XM_005266381 /// XM_005266383 /// XM_005266387 /// XM_005266389 /// XM_005266391 /// XM_005266392 /// XM_005266396 /// XM_005266397 /// XM_006719810 /// XM_006719811 /// XM_006719812 /// XM_006719813 /// XM_006719814 /// XM_006719815 /// XM_006719816 /// XM_006719817 /// XM_006719818 /// XM_006719819 /// XM_006719820 /// XM_006719821 /// XM_006719822 /// XM_006719823 /// XM_006719824 /// XM_006719825 /// XM_006719826 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202675_at NM_003000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003000.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHB /PROD=succinate dehydrogenase complex, subunit B, ironsulfur (Ip) /DB_XREF=gi:9257241 /UG=Hs.64 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) /FL=gb:U17248.1 gb:NM_003000.1 NM_003000 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) SDHB 6390 NM_003000 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from sequence or structural similarity /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity 202676_x_at NM_006712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006712.1 /DEF=Homo sapiens Fas-activated serinethreonine kinase (FASTK), mRNA. /FEA=mRNA /GEN=FASTK /PROD=Fas-activated serinethreonine kinase /DB_XREF=gi:5729821 /UG=Hs.75087 Fas-activated serinethreonine kinase /FL=gb:NM_006712.1 NM_006712 Fas-activated serine/threonine kinase FASTK 10922 NM_001258461 /// NM_006712 /// NM_033015 /// XM_005249932 /// XM_005249933 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033867 // Fas-activated serine/threonine kinase activity // inferred from electronic annotation 202677_at NM_002890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002890.1 /DEF=Homo sapiens RAS p21 protein activator (GTPase activating protein) 1 (RASA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=RASA1 /PROD=RAS p21 protein activator 1, isoform 1 /DB_XREF=gi:4506430 /UG=Hs.758 RAS p21 protein activator (GTPase activating protein) 1 /FL=gb:M23379.1 gb:NM_002890.1 NM_002890 RAS p21 protein activator (GTPase activating protein) 1 RASA1 5921 NM_002890 /// NM_022650 0000281 // mitotic cytokinesis // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0008360 // regulation of cell shape // non-traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051252 // regulation of RNA metabolic process // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0001948 // glycoprotein binding // inferred from physical interaction /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019870 // potassium channel inhibitor activity // non-traceable author statement /// 0051020 // GTPase binding // inferred from physical interaction 202678_at NM_004492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004492.1 /DEF=Homo sapiens general transcription factor IIA, 2 (12kD subunit) (GTF2A2), mRNA. /FEA=mRNA /GEN=GTF2A2 /PROD=general transcription factor IIA, 2 (12kDsubunit) /DB_XREF=gi:4758485 /UG=Hs.76362 general transcription factor IIA, 2 (12kD subunit) /FL=gb:BC000287.1 gb:BC001919.1 gb:U21242.1 gb:NM_004492.1 gb:U14193.1 NM_004492 general transcription factor IIA, 2, 12kDa GTF2A2 2958 NM_004492 /// XM_005254324 /// XM_005254325 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005672 // transcription factor TFIIA complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 202679_at NM_000271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000271.1 /DEF=Homo sapiens Niemann-Pick disease, type C1 (NPC1), mRNA. /FEA=mRNA /GEN=NPC1 /PROD=Niemann-Pick disease, type C1 /DB_XREF=gi:4557802 /UG=Hs.76918 Niemann-Pick disease, type C1 /FL=gb:AF002020.1 gb:NM_000271.1 NM_000271 Niemann-Pick disease, type C1 NPC1 4864 NM_000271 /// XM_005258277 /// XM_005258278 /// XM_005258279 /// XM_006722479 0006486 // protein glycosylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0007041 // lysosomal transport // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from sequence or structural similarity /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from direct assay /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071404 // cellular response to low-density lipoprotein particle stimulus // inferred from electronic annotation /// 0090150 // establishment of protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0015248 // sterol transporter activity // traceable author statement /// 0015485 // cholesterol binding // inferred from direct assay 202680_at NM_002095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002095.1 /DEF=Homo sapiens general transcription factor IIE, polypeptide 2 (beta subunit, 34kD) (GTF2E2), mRNA. /FEA=mRNA /GEN=GTF2E2 /PROD=general transcription factor IIE, polypeptide 2(beta subunit, 34kD) /DB_XREF=gi:4504194 /UG=Hs.77100 general transcription factor IIE, polypeptide 2 (beta subunit, 34kD) /FL=gb:NM_002095.1 NM_002095 general transcription factor IIE, polypeptide 2, beta 34kDa GTF2E2 2961 NM_002095 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005673 // transcription factor TFIIE complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202681_at AI346043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346043 /FEA=EST /DB_XREF=gi:4083249 /DB_XREF=est:qp48c09.x1 /CLONE=IMAGE:1926256 /UG=Hs.77500 ubiquitin specific protease 4 (proto-oncogene) /FL=gb:U20657.1 gb:AF017305.1 gb:NM_003363.1 AI346043 chromosome 3 open reading frame 62 /// microRNA 4271 /// ubiquitin specific peptidase 4 (proto-oncogene) C3orf62 /// MIR4271 /// USP4 7375 /// 375341 /// 100422952 NM_001251877 /// NM_003363 /// NM_198562 /// NM_199443 /// NR_036233 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202682_s_at NM_003363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003363.1 /DEF=Homo sapiens ubiquitin specific protease 4 (proto-oncogene) (USP4), mRNA. /FEA=mRNA /GEN=USP4 /PROD=ubiquitin specific protease, proto-oncogene /DB_XREF=gi:4507852 /UG=Hs.77500 ubiquitin specific protease 4 (proto-oncogene) /FL=gb:U20657.1 gb:AF017305.1 gb:NM_003363.1 NM_003363 ubiquitin specific peptidase 4 (proto-oncogene) USP4 7375 NM_001251877 /// NM_003363 /// NM_199443 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202683_s_at NM_003799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003799.1 /DEF=Homo sapiens RNA (guanine-7-) methyltransferase (RNMT), mRNA. /FEA=mRNA /GEN=RNMT /PROD=RNA (guanine-7-) methyltransferase /DB_XREF=gi:4506566 /UG=Hs.8086 RNA (guanine-7-) methyltransferase /FL=gb:AB007858.1 gb:AF067791.1 gb:AB022604.1 gb:NM_003799.1 gb:AB020966.1 NM_003799 RNA (guanine-7-) methyltransferase RNMT 8731 NM_003799 /// XM_005258160 /// XM_005258162 /// XM_006722361 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from mutant phenotype /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from mutant phenotype /// 0036265 // RNA (guanine-N7)-methylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202684_s_at AB020966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020966.1 /DEF=Homo sapiens hMet mRNA for RNA (guanine-N7-) methyltransferase, complete cds. /FEA=mRNA /GEN=hMet /PROD=RNA (guanine-N7-) methyltransferase /DB_XREF=gi:5478274 /UG=Hs.8086 RNA (guanine-7-) methyltransferase /FL=gb:AB007858.1 gb:AF067791.1 gb:AB022604.1 gb:NM_003799.1 gb:AB020966.1 AB020966 RNA (guanine-7-) methyltransferase RNMT 8731 NM_003799 /// XM_005258160 /// XM_005258162 /// XM_006722361 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from mutant phenotype /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from mutant phenotype /// 0036265 // RNA (guanine-N7)-methylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202685_s_at AI467916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI467916 /FEA=EST /DB_XREF=gi:4330006 /DB_XREF=est:tj84a10.x1 /CLONE=IMAGE:2148186 /UG=Hs.83341 AXL receptor tyrosine kinase /FL=gb:NM_021913.1 AI467916 AXL receptor tyrosine kinase AXL 558 NM_001278599 /// NM_001699 /// NM_021913 0001764 // neuron migration // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0021885 // forebrain cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0048469 // cell maturation // inferred from expression pattern /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202686_s_at NM_021913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021913.1 /DEF=Homo sapiens AXL receptor tyrosine kinase (AXL), transcript variant 1, mRNA. /FEA=mRNA /GEN=AXL /PROD=AXL receptor tyrosine kinase isoform 1precursor /DB_XREF=gi:11863122 /UG=Hs.83341 AXL receptor tyrosine kinase /FL=gb:NM_021913.1 NM_021913 AXL receptor tyrosine kinase AXL 558 NM_001278599 /// NM_001699 /// NM_021913 0001764 // neuron migration // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0021885 // forebrain cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0048469 // cell maturation // inferred from expression pattern /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202687_s_at U57059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U57059.1 /DEF=Homo sapiens Apo-2 ligand mRNA, complete cds. /FEA=mRNA /PROD=Apo-2 ligand /DB_XREF=gi:1336207 /UG=Hs.83429 tumor necrosis factor (ligand) superfamily, member 10 /FL=gb:U37518.1 gb:U57059.1 gb:NM_003810.1 U57059 tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 8743 NM_001190942 /// NM_001190943 /// NM_003810 /// NR_033994 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202688_at NM_003810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003810.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), mRNA. /FEA=mRNA /GEN=TNFSF10 /PROD=tumor necrosis factor (ligand) superfamily,member 10 /DB_XREF=gi:4507592 /UG=Hs.83429 tumor necrosis factor (ligand) superfamily, member 10 /FL=gb:U37518.1 gb:U57059.1 gb:NM_003810.1 NM_003810 tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 8743 NM_001190942 /// NM_001190943 /// NM_003810 /// NR_033994 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202689_at NM_013286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013286.1 /DEF=Homo sapiens chromosome 3p21.1 gene sequence (HUMAGCGB), mRNA. /FEA=mRNA /GEN=HUMAGCGB /PROD=chromosome 3p21.1 gene sequence /DB_XREF=gi:7110644 /UG=Hs.84162 chromosome 3p21.1 gene sequence /FL=gb:BC001367.1 gb:L13434.1 gb:NM_013286.1 NM_013286 RNA binding motif protein 15B RBM15B 29890 NM_013286 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202690_s_at BC001721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001721.1 /DEF=Homo sapiens, small nuclear ribonucleoprotein D1 polypeptide (16kD), clone MGC:2222, mRNA, complete cds. /FEA=mRNA /PROD=small nuclear ribonucleoprotein D1 polypeptide(16kD) /DB_XREF=gi:12804598 /UG=Hs.86948 small nuclear ribonucleoprotein D1 polypeptide (16kD) /FL=gb:BC001721.1 gb:J03798.1 gb:NM_006938.1 BC001721 small nuclear ribonucleoprotein D1 polypeptide 16kDa SNRPD1 6632 NM_001291916 /// NM_006938 0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202691_at NM_006938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006938.1 /DEF=Homo sapiens small nuclear ribonucleoprotein D1 polypeptide (16kD) (SNRPD1), mRNA. /FEA=mRNA /GEN=SNRPD1 /PROD=small nuclear ribonucleoprotein D1 polypeptide(16kD) /DB_XREF=gi:5902101 /UG=Hs.86948 small nuclear ribonucleoprotein D1 polypeptide (16kD) /FL=gb:BC001721.1 gb:J03798.1 gb:NM_006938.1 NM_006938 small nuclear ribonucleoprotein D1 polypeptide 16kDa SNRPD1 6632 NM_001291916 /// NM_006938 0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202692_s_at NM_014233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014233.1 /DEF=Homo sapiens upstream binding transcription factor, RNA polymerase I (UBTF), mRNA. /FEA=mRNA /GEN=UBTF /PROD=upstream binding transcription factor, RNApolymerase I /DB_XREF=gi:7657670 /UG=Hs.89781 upstream binding transcription factor, RNA polymerase I /FL=gb:NM_014233.1 NM_014233 upstream binding transcription factor, RNA polymerase I UBTF 7343 NM_001076683 /// NM_001076684 /// NM_014233 /// NR_045058 /// XM_006722059 /// XM_006722060 /// XM_006722061 0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202693_s_at AW194730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194730 /FEA=EST /DB_XREF=gi:6473630 /DB_XREF=est:xn43d11.x1 /CLONE=IMAGE:2696469 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1 AW194730 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202694_at AW183478 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW183478 /FEA=EST /DB_XREF=gi:6451992 /DB_XREF=est:xj77a08.x1 /CLONE=IMAGE:2663222 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1 AW183478 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202695_s_at NM_004760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004760.1 /DEF=Homo sapiens serinethreonine kinase 17a (apoptosis-inducing) (STK17A), mRNA. /FEA=mRNA /GEN=STK17A /PROD=serinethreonine kinase 17a(apoptosis-inducing) /DB_XREF=gi:4758191 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1 NM_004760 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202696_at NM_005109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005109.1 /DEF=Homo sapiens oxidative-stress responsive 1 (OSR1), mRNA. /FEA=mRNA /GEN=OSR1 /PROD=oxidative-stress responsive 1 /DB_XREF=gi:4826877 /UG=Hs.95220 oxidative-stress responsive 1 /FL=gb:AB017642.1 gb:NM_005109.1 gb:AB029024.1 NM_005109 oxidative stress responsive 1 OXSR1 9943 NM_005109 /// XM_005265638 0006468 // protein phosphorylation // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // not recorded /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202697_at NM_007006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007006.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 5, 25 kD subunit (CPSF5), mRNA. /FEA=mRNA /GEN=CPSF5 /PROD=cleavage and polyadenylation specific factor 5,25 kD subunit /DB_XREF=gi:5901925 /UG=Hs.9605 cleavage and polyadenylation specific factor 5, 25 kD subunit /FL=gb:BC001403.1 gb:NM_007006.1 NM_007006 nudix (nucleoside diphosphate linked moiety X)-type motif 21 NUDT21 11051 NM_007006 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202698_x_at NM_001861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001861.1 /DEF=Homo sapiens cytochrome c oxidase subunit IV (COX4), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX4 /PROD=cytochrome c oxidase subunit IV /DB_XREF=gi:4502980 /UG=Hs.113205 cytochrome c oxidase subunit IV /FL=gb:M21575.1 gb:M34600.1 gb:U90915.1 gb:NM_001861.1 NM_001861 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 /// XM_005255798 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202699_s_at AW510783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW510783 /FEA=EST /DB_XREF=gi:7148861 /DB_XREF=est:hd39g03.x1 /CLONE=IMAGE:2911924 /UG=Hs.119387 KIAA0792 gene product /FL=gb:AB018335.1 gb:NM_014698.1 AW510783 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 202700_s_at NM_014698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014698.1 /DEF=Homo sapiens KIAA0792 gene product (KIAA0792), mRNA. /FEA=mRNA /GEN=KIAA0792 /PROD=KIAA0792 gene product /DB_XREF=gi:7662307 /UG=Hs.119387 KIAA0792 gene product /FL=gb:AB018335.1 gb:NM_014698.1 NM_014698 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 202701_at NM_006129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006129.2 /DEF=Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant BMP1-3, mRNA. /FEA=mRNA /GEN=BMP1 /PROD=bone morphogenetic protein 1, isoform 3,precursor /DB_XREF=gi:5902809 /UG=Hs.1274 bone morphogenetic protein 1 /FL=gb:U50330.1 gb:NM_006129.2 NM_006129 bone morphogenetic protein 1 BMP1 649 NM_001199 /// NM_006128 /// NM_006129 /// NM_006130 /// NM_006131 /// NM_006132 /// NR_033403 /// NR_033404 /// XM_006716386 /// XR_428315 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202702_at NM_003449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003449.1 /DEF=Homo sapiens zinc finger protein 173 (ZNF173), mRNA. /FEA=mRNA /GEN=ZNF173 /PROD=zinc finger protein 173 /DB_XREF=gi:4508004 /UG=Hs.1287 zinc finger protein 173 /FL=gb:NM_003449.1 gb:U09825.1 NM_003449 tripartite motif containing 26 TRIM26 7726 NM_001242783 /// NM_003449 /// XM_005249374 /// XM_005249375 /// XM_005249376 /// XM_005249377 /// XM_005249378 /// XM_005272870 /// XM_005272871 /// XM_005272872 /// XM_005274887 /// XM_005274888 /// XM_005274890 /// XM_005274891 /// XM_005275022 /// XM_005275023 /// XM_005275025 /// XM_005275026 /// XM_005275159 /// XM_005275160 /// XM_005275161 /// XM_005275452 /// XM_005275453 /// XM_005275455 /// XM_005275456 /// XM_005275590 /// XM_005275591 /// XM_005275592 /// XM_005275593 /// XM_005275594 /// XM_006715180 /// XM_006725500 0045087 // innate immune response // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement 202703_at NM_003584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003584.1 /DEF=Homo sapiens dual specificity phosphatase 11 (RNARNP complex 1-interacting) (DUSP11), mRNA. /FEA=mRNA /GEN=DUSP11 /PROD=dual specificity phosphatase 11 /DB_XREF=gi:4503414 /UG=Hs.14611 dual specificity phosphatase 11 (RNARNP complex 1-interacting) /FL=gb:BC000346.1 gb:AF023917.1 gb:NM_003584.1 NM_003584 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) DUSP11 8446 NM_003584 /// XM_005264604 /// XR_244962 0006396 // RNA processing // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0098507 // polynucleotide 5' dephosphorylation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0098519 // nucleotide phosphatase activity, acting on free nucleotides // inferred from mutant phenotype 202704_at AA675892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA675892 /FEA=EST /DB_XREF=gi:2775239 /DB_XREF=est:b03503s /CLONE=b03503 /UG=Hs.178137 transducer of ERBB2, 1 /FL=gb:D38305.1 gb:NM_005749.1 AA675892 transducer of ERBB2, 1 TOB1 10140 NM_001243877 /// NM_001243885 /// NM_005749 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0060212 // negative regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030014 // CCR4-NOT complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation 202705_at NM_004701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004701.2 /DEF=Homo sapiens cyclin B2 (CCNB2), mRNA. /FEA=mRNA /GEN=CCNB2 /PROD=cyclin B2 /DB_XREF=gi:10938017 /UG=Hs.194698 cyclin B2 /FL=gb:NM_004701.2 gb:AF002822.1 gb:AB020981.1 gb:AL080146.1 NM_004701 cyclin B2 CCNB2 9133 NM_004701 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202706_s_at D86227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86227.1 /DEF=Homo sapiens clone TA-UMPSpoly mRNA for UMP synthase, complete cds. /FEA=mRNA /GEN=UMPS /PROD=UMP synthase /DB_XREF=gi:2081619 /UG=Hs.2057 uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) /FL=gb:BC000364.1 gb:D86227.1 gb:D86228.1 gb:D86230.1 gb:J03626.1 gb:NM_000373.1 D86227 uridine monophosphate synthetase UMPS 7372 NM_000373 /// NR_033434 /// NR_033437 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004588 // orotate phosphoribosyltransferase activity // inferred from direct assay /// 0004588 // orotate phosphoribosyltransferase activity // traceable author statement /// 0004590 // orotidine-5'-phosphate decarboxylase activity // inferred from direct assay /// 0004590 // orotidine-5'-phosphate decarboxylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 202707_at NM_000373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000373.1 /DEF=Homo sapiens uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) (UMPS), mRNA. /FEA=mRNA /GEN=UMPS /PROD=uridine monophosphate synthetase (orotatephosphoribosyl transferase andorotidine-5-decarboxylase) /DB_XREF=gi:4507834 /UG=Hs.2057 uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) /FL=gb:BC000364.1 gb:D86227.1 gb:D86228.1 gb:D86230.1 gb:J03626.1 gb:NM_000373.1 NM_000373 uridine monophosphate synthetase UMPS 7372 NM_000373 /// NR_033434 /// NR_033437 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004588 // orotate phosphoribosyltransferase activity // inferred from direct assay /// 0004588 // orotate phosphoribosyltransferase activity // traceable author statement /// 0004590 // orotidine-5'-phosphate decarboxylase activity // inferred from direct assay /// 0004590 // orotidine-5'-phosphate decarboxylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 202708_s_at NM_003528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003528.1 /DEF=Homo sapiens H2B histone family, member Q (H2BFQ), mRNA. /FEA=mRNA /GEN=H2BFQ /PROD=H2B histone family, member Q /DB_XREF=gi:4504276 /UG=Hs.2178 H2B histone family, member Q /FL=gb:NM_003528.1 NM_003528 histone cluster 2, H2be HIST2H2BE 8349 NM_003528 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202709_at NM_002023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002023.2 /DEF=Homo sapiens fibromodulin (FMOD), mRNA. /FEA=mRNA /GEN=FMOD /PROD=fibromodulin precursor /DB_XREF=gi:5016093 /UG=Hs.230 fibromodulin /FL=gb:NM_002023.2 NM_002023 fibromodulin FMOD 2331 NM_002023 /// NR_103757 0005975 // carbohydrate metabolic process // traceable author statement /// 0007181 // transforming growth factor beta receptor complex assembly // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation 202710_at BC000899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000899.1 /DEF=Homo sapiens, Golgi vesicular membrane trafficking protein p18, clone MGC:5210, mRNA, complete cds. /FEA=mRNA /PROD=Golgi vesicular membrane trafficking proteinp18 /DB_XREF=gi:12654162 /UG=Hs.23103 Bet1 (S. cerevisiae) homolog /FL=gb:BC000899.1 gb:NM_005868.2 gb:AF007551.1 BC000899 Bet1 golgi vesicular membrane trafficking protein BET1 10282 NM_005868 /// XM_005250109 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 202711_at NM_004429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004429.1 /DEF=Homo sapiens ephrin-B1 (EFNB1), mRNA. /FEA=mRNA /GEN=EFNB1 /PROD=ephrin-B1 /DB_XREF=gi:4758247 /UG=Hs.144700 ephrin-B1 /FL=gb:U09303.1 gb:NM_004429.1 gb:U09304.1 gb:L37361.1 NM_004429 ephrin-B1 EFNB1 1947 NM_004429 0001755 // neural crest cell migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // not recorded 202712_s_at NM_020990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020990.2 /DEF=Homo sapiens creatine kinase, mitochondrial 1 (ubiquitous) (CKMT1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CKMT1 /PROD=ubiquitous mitochondrial creatine kinaseprecursor /DB_XREF=gi:11641403 /UG=Hs.153998 creatine kinase, mitochondrial 1 (ubiquitous) /FL=gb:NM_020990.2 gb:BC001926.1 NM_020990 creatine kinase, mitochondrial 1A /// creatine kinase, mitochondrial 1B CKMT1A /// CKMT1B 1159 /// 548596 NM_001015001 /// NM_020990 /// XM_005254150 /// XM_005254498 0006600 // creatine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202713_s_at AA129755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129755 /FEA=EST /DB_XREF=gi:1690165 /DB_XREF=est:zl16b10.s1 /CLONE=IMAGE:502075 /UG=Hs.154668 KIAA0391 gene product /FL=gb:AB002389.1 gb:NM_014672.1 AA129755 KIAA0391 /// proteasome (prosome, macropain) subunit, alpha type, 6 KIAA0391 /// PSMA6 5687 /// 9692 NM_001256678 /// NM_001256679 /// NM_001256680 /// NM_001256681 /// NM_001282232 /// NM_001282233 /// NM_001282234 /// NM_002791 /// NM_014672 /// NR_104110 /// XM_005268237 /// XM_006720334 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005839 // proteasome core complex // non-traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from direct assay /// 0019773 // proteasome core complex, alpha-subunit complex // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0004175 // endopeptidase activity // non-traceable author statement /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035639 // purine ribonucleoside triphosphate binding // non-traceable author statement /// 0051059 // NF-kappaB binding // inferred from physical interaction 202714_s_at NM_014672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014672.1 /DEF=Homo sapiens KIAA0391 gene product (KIAA0391), mRNA. /FEA=mRNA /GEN=KIAA0391 /PROD=KIAA0391 gene product /DB_XREF=gi:7662093 /UG=Hs.154668 KIAA0391 gene product /FL=gb:AB002389.1 gb:NM_014672.1 NM_014672 KIAA0391 KIAA0391 9692 NM_001256678 /// NM_001256679 /// NM_001256680 /// NM_001256681 /// NM_014672 /// XM_005268237 /// XM_006720334 0008033 // tRNA processing // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 202715_at NM_004341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004341.1 /DEF=Homo sapiens carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CAD /PROD=carbamoyl-phosphate synthetase 2, aspartatetranscarbamylase, and dihydroorotase /DB_XREF=gi:4757895 /UG=Hs.154868 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase /FL=gb:D78586.1 gb:NM_004341.1 NM_004341 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase CAD 790 NM_004341 /// XM_005264555 /// XM_005264556 /// XM_005264557 /// XM_005264558 /// XM_006712101 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from direct assay /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from sequence or structural similarity /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0051414 // response to cortisol // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0070409 // carbamoyl phosphate biosynthetic process // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042995 // cell projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004070 // aspartate carbamoyltransferase activity // inferred from sequence or structural similarity /// 0004070 // aspartate carbamoyltransferase activity // traceable author statement /// 0004088 // carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity // inferred from sequence or structural similarity /// 0004088 // carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity // traceable author statement /// 0004151 // dihydroorotase activity // inferred from direct assay /// 0004151 // dihydroorotase activity // inferred from sequence or structural similarity /// 0004151 // dihydroorotase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016743 // carboxyl- or carbamoyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070335 // aspartate binding // inferred from sequence or structural similarity 202716_at NM_002827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002827.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 1 (PTPN1), mRNA. /FEA=mRNA /GEN=PTPN1 /PROD=protein tyrosine phosphatase, non-receptor type1 /DB_XREF=gi:4506288 /UG=Hs.155894 protein tyrosine phosphatase, non-receptor type 1 /FL=gb:M33689.1 gb:M31724.1 gb:NM_002827.1 NM_002827 protein tyrosine phosphatase, non-receptor type 1 PTPN1 5770 NM_001278618 /// NM_002827 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1990264 // peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity // inferred from sequence or structural similarity 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from physical interaction 202717_s_at NM_003903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003903.1 /DEF=Homo sapiens CDC16 (cell division cycle 16, S. cerevisiae, homolog) (CDC16), mRNA. /FEA=mRNA /GEN=CDC16 /PROD=CDC16 (cell division cycle 16, S. cerevisiae,homolog) /DB_XREF=gi:4502700 /UG=Hs.1592 CDC16 (cell division cycle 16, S. cerevisiae, homolog) /FL=gb:NM_003903.1 gb:U18291.1 NM_003903 cell division cycle 16 CDC16 8881 NM_001078645 /// NM_003903 /// XM_005266204 /// XM_005266206 /// XM_006719992 /// XM_006719993 /// XR_245358 /// XR_245359 /// XR_245360 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202718_at NM_000597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000597.1 /DEF=Homo sapiens insulin-like growth factor binding protein 2 (36kD) (IGFBP2), mRNA. /FEA=mRNA /GEN=IGFBP2 /PROD=insulin-like growth factor binding protein 2(36kD) /DB_XREF=gi:10835156 /UG=Hs.162 insulin-like growth factor binding protein 2 (36kD) /FL=gb:NM_000597.1 gb:BC004312.1 gb:M35410.1 NM_000597 insulin-like growth factor binding protein 2, 36kDa IGFBP2 3485 NM_000597 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred by curator /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from direct assay /// 0031995 // insulin-like growth factor II binding // inferred from sequence or structural similarity 202719_s_at BC001451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001451.1 /DEF=Homo sapiens, testin, clone MGC:1146, mRNA, complete cds. /FEA=mRNA /PROD=testin /DB_XREF=gi:12655188 /UG=Hs.165986 testin /FL=gb:AF245356.1 gb:AF245357.1 gb:BC001451.1 gb:NM_015641.1 BC001451 testis derived transcript (3 LIM domains) TES 26136 NM_015641 /// NM_152829 /// XM_005250258 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0008270 // zinc ion binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202720_at NM_015641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015641.1 /DEF=Homo sapiens testin (DKFZP586B2022), mRNA. /FEA=mRNA /GEN=DKFZP586B2022 /PROD=testin /DB_XREF=gi:7661665 /UG=Hs.165986 testin /FL=gb:AF245356.1 gb:AF245357.1 gb:BC001451.1 gb:NM_015641.1 NM_015641 testis derived transcript (3 LIM domains) TES 26136 NM_015641 /// NM_152829 /// XM_005250258 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0008270 // zinc ion binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202721_s_at BE645771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645771 /FEA=EST /DB_XREF=gi:9970082 /DB_XREF=est:7e76b02.x1 /CLONE=IMAGE:3288363 /UG=Hs.1674 glutamine-fructose-6-phosphate transaminase 1 /FL=gb:M90516.1 gb:NM_002056.1 BE645771 glutamine--fructose-6-phosphate transaminase 1 GFPT1 2673 NM_001244710 /// NM_002056 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006042 // glucosamine biosynthetic process // inferred from electronic annotation /// 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004360 // glutamine-fructose-6-phosphate transaminase (isomerizing) activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202722_s_at NM_002056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002056.1 /DEF=Homo sapiens glutamine-fructose-6-phosphate transaminase 1 (GFPT1), mRNA. /FEA=mRNA /GEN=GFPT1 /PROD=glucosamine-fructose-6-phosphateaminotransferase /DB_XREF=gi:4503980 /UG=Hs.1674 glutamine-fructose-6-phosphate transaminase 1 /FL=gb:M90516.1 gb:NM_002056.1 NM_002056 glutamine--fructose-6-phosphate transaminase 1 GFPT1 2673 NM_001244710 /// NM_002056 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006042 // glucosamine biosynthetic process // inferred from electronic annotation /// 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004360 // glutamine-fructose-6-phosphate transaminase (isomerizing) activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202723_s_at AW117498 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW117498 /FEA=EST /DB_XREF=gi:6086082 /DB_XREF=est:xd92e10.x1 /CLONE=IMAGE:2605098 /UG=Hs.170133 forkhead box O1A (rhabdomyosarcoma) /FL=gb:AF032885.1 gb:U02310.1 gb:NM_002015.2 AW117498 forkhead box O1 FOXO1 2308 NM_002015 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // not recorded /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070417 // cellular response to cold // inferred from sequence or structural similarity /// 0071455 // cellular response to hyperoxia // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 202724_s_at NM_002015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002015.2 /DEF=Homo sapiens forkhead box O1A (rhabdomyosarcoma) (FOXO1A), mRNA. /FEA=mRNA /GEN=FOXO1A /PROD=forkhead box O1A /DB_XREF=gi:9257221 /UG=Hs.170133 forkhead box O1A (rhabdomyosarcoma) /FL=gb:AF032885.1 gb:U02310.1 gb:NM_002015.2 NM_002015 forkhead box O1 FOXO1 2308 NM_002015 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // not recorded /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070417 // cellular response to cold // inferred from sequence or structural similarity /// 0071455 // cellular response to hyperoxia // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 202725_at NM_000937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000937.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide A (220kD) (POLR2A), mRNA. /FEA=mRNA /GEN=POLR2A /PROD=polymerase (RNA) II (DNA directed) polypeptide A(220kD) /DB_XREF=gi:4505938 /UG=Hs.171880 polymerase (RNA) II (DNA directed) polypeptide A (220kD) /FL=gb:NM_000937.1 NM_000937 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa POLR2A 5430 NM_000937 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001172 // transcription, RNA-templated // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0003968 // RNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202726_at NM_000234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000234.1 /DEF=Homo sapiens ligase I, DNA, ATP-dependent (LIG1), mRNA. /FEA=mRNA /GEN=LIG1 /PROD=DNA ligase I /DB_XREF=gi:4557718 /UG=Hs.1770 ligase I, DNA, ATP-dependent /FL=gb:M36067.1 gb:NM_000234.1 NM_000234 ligase I, DNA, ATP-dependent LIG1 3978 NM_000234 /// NM_001289063 /// NM_001289064 /// NR_110296 /// XM_005258934 /// XM_006723215 /// XM_006723216 /// XM_006723217 /// XR_243932 /// XR_243934 /// XR_430200 /// XR_430201 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // not recorded /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0033151 // V(D)J recombination // inferred from direct assay /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003910 // DNA ligase (ATP) activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202727_s_at NM_000416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000416.1 /DEF=Homo sapiens interferon gamma receptor 1 (IFNGR1), mRNA. /FEA=mRNA /GEN=IFNGR1 /PROD=interferon gamma receptor 1 /DB_XREF=gi:4557879 /UG=Hs.180866 interferon gamma receptor 1 /FL=gb:BC005333.1 gb:J03143.1 gb:NM_000416.1 NM_000416 interferon gamma receptor 1 IFNGR1 3459 NM_000416 /// XM_006715470 /// XM_006715471 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0004906 // interferon-gamma receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from electronic annotation 202728_s_at AI986120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI986120 /FEA=EST /DB_XREF=gi:5813397 /DB_XREF=est:wr80e09.x1 /CLONE=IMAGE:2494024 /UG=Hs.241257 latent transforming growth factor beta binding protein 1 /FL=gb:M34057.1 gb:NM_000627.1 AI986120 latent transforming growth factor beta binding protein 1 LTBP1 4052 NM_000627 /// NM_001166264 /// NM_001166265 /// NM_001166266 /// NM_206943 /// XM_005264315 /// XM_005264316 /// XM_005264317 /// XM_005264318 /// XM_005264319 /// XM_006712019 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035583 // sequestering of TGFbeta in extracellular matrix // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 202729_s_at NM_000627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000627.1 /DEF=Homo sapiens latent transforming growth factor beta binding protein 1 (LTBP1), mRNA. /FEA=mRNA /GEN=LTBP1 /PROD=latent transforming growth factor beta bindingprotein 1 precursor /DB_XREF=gi:4557730 /UG=Hs.241257 latent transforming growth factor beta binding protein 1 /FL=gb:M34057.1 gb:NM_000627.1 NM_000627 latent transforming growth factor beta binding protein 1 LTBP1 4052 NM_000627 /// NM_001166264 /// NM_001166265 /// NM_001166266 /// NM_206943 /// XM_005264315 /// XM_005264316 /// XM_005264317 /// XM_005264318 /// XM_005264319 /// XM_006712019 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035583 // sequestering of TGFbeta in extracellular matrix // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 202730_s_at NM_014456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014456.1 /DEF=Homo sapiens programmed cell death 4 (PDCD4), mRNA. /FEA=mRNA /GEN=PDCD4 /PROD=programmed cell death 4 /DB_XREF=gi:7657448 /UG=Hs.296251 programmed cell death 4 /FL=gb:U96628.1 gb:NM_014456.1 NM_014456 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202731_at NM_014456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014456.1 /DEF=Homo sapiens programmed cell death 4 (PDCD4), mRNA. /FEA=mRNA /GEN=PDCD4 /PROD=programmed cell death 4 /DB_XREF=gi:7657448 /UG=Hs.296251 programmed cell death 4 /FL=gb:U96628.1 gb:NM_014456.1 NM_014456 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202732_at NM_007066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007066.1 /DEF=Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor gamma (PKIG), mRNA. /FEA=mRNA /GEN=PKIG /PROD=protein kinase (cAMP-dependent, catalytic)inhibitor gamma /DB_XREF=gi:5902019 /UG=Hs.3407 protein kinase (cAMP-dependent, catalytic) inhibitor gamma /FL=gb:AB019517.1 gb:AF182032.1 gb:NM_007066.1 NM_007066 protein kinase (cAMP-dependent, catalytic) inhibitor gamma PKIG 11142 NM_001281444 /// NM_001281445 /// NM_007066 /// NM_181804 /// NM_181805 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 202733_at NM_004199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004199.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II (P4HA2), mRNA. /FEA=mRNA /GEN=P4HA2 /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), alpha polypeptideII /DB_XREF=gi:4758867 /UG=Hs.3622 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II /FL=gb:U90441.1 gb:NM_004199.1 NM_004199 uncharacterized LOC101927705 /// prolyl 4-hydroxylase, alpha polypeptide II LOC101927705 /// P4HA2 8974 /// 101927705 NM_001017973 /// NM_001017974 /// NM_001142598 /// NM_001142599 /// NM_004199 /// XM_005272116 /// XM_005272117 /// XM_005272118 /// XM_005272119 /// XM_005272120 /// XM_005272122 /// XM_006714728 /// XM_006714729 /// XM_006714730 /// XM_006714731 /// XR_246585 /// XR_249830 /// XR_251870 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004656 // procollagen-proline 4-dioxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 202734_at NM_004240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004240.1 /DEF=Homo sapiens thyroid hormone receptor interactor 10 (TRIP10), mRNA. /FEA=mRNA /GEN=TRIP10 /PROD=thyroid hormone receptor interactor 10 /DB_XREF=gi:11342675 /UG=Hs.73999 thyroid hormone receptor interactor 10 /FL=gb:NM_004240.1 NM_004240 thyroid hormone receptor interactor 10 TRIP10 9322 NM_001288962 /// NM_001288963 /// NM_004240 /// NR_110231 /// XM_005259683 /// XM_006722940 /// XR_430161 0006897 // endocytosis // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001891 // phagocytic cup // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202735_at NM_006579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006579.1 /DEF=Homo sapiens emopamil-binding protein (sterol isomerase) (EBP), mRNA. /FEA=mRNA /GEN=EBP /PROD=emopamil-binding protein (sterol isomerase) /DB_XREF=gi:5729809 /UG=Hs.75105 emopamil-binding protein (sterol isomerase) /FL=gb:NM_006579.1 NM_006579 emopamil binding protein (sterol isomerase) EBP 10682 NM_006579 0001501 // skeletal system development // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004769 // steroid delta-isomerase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0015238 // drug transmembrane transporter activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0047750 // cholestenol delta-isomerase activity // inferred from electronic annotation 202736_s_at AA112507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA112507 /FEA=EST /DB_XREF=gi:1665056 /DB_XREF=est:zm28c01.r1 /CLONE=IMAGE:526944 /UG=Hs.76719 U6 snRNA-associated Sm-like protein /FL=gb:BC000387.1 gb:BC003652.1 gb:AF182290.1 gb:AF117235.1 gb:NM_012321.1 gb:AF251218.1 AA112507 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM4 25804 NM_001252129 /// NM_012321 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005688 // U6 snRNP // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202737_s_at NM_012321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012321.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein (LSM4), mRNA. /FEA=mRNA /GEN=LSM4 /PROD=U6 snRNA-associated Sm-like protein /DB_XREF=gi:6912485 /UG=Hs.76719 U6 snRNA-associated Sm-like protein /FL=gb:BC000387.1 gb:BC003652.1 gb:AF182290.1 gb:AF117235.1 gb:NM_012321.1 gb:AF251218.1 NM_012321 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM4 25804 NM_001252129 /// NM_012321 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005688 // U6 snRNP // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202738_s_at BG149218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG149218 /FEA=EST /DB_XREF=gi:12661248 /DB_XREF=est:nad24g09.x1 /CLONE=IMAGE:3366712 /UG=Hs.78060 phosphorylase kinase, beta /FL=gb:NM_000293.1 BG149218 phosphorylase kinase, beta PHKB 5257 NM_000293 /// NM_001031835 /// XM_005255983 /// XM_005255984 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202739_s_at NM_000293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000293.1 /DEF=Homo sapiens phosphorylase kinase, beta (PHKB), mRNA. /FEA=mRNA /GEN=PHKB /PROD=phosphorylase kinase, beta /DB_XREF=gi:4505782 /UG=Hs.78060 phosphorylase kinase, beta /FL=gb:NM_000293.1 NM_000293 phosphorylase kinase, beta PHKB 5257 NM_000293 /// NM_001031835 /// XM_005255983 /// XM_005255984 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202740_at NM_000666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000666.1 /DEF=Homo sapiens aminoacylase 1 (ACY1), mRNA. /FEA=mRNA /GEN=ACY1 /PROD=aminoacylase 1 /DB_XREF=gi:4501900 /UG=Hs.79 aminoacylase 1 /FL=gb:BC000545.1 gb:BC003023.1 gb:L07548.1 gb:D14524.1 gb:D16307.1 gb:NM_000666.1 NM_000666 ABHD14A-ACY1 readthrough (NMD candidate) /// aminoacylase 1 ABHD14A-ACY1 /// ACY1 95 /// 100526760 NM_000666 /// NM_001198895 /// NM_001198896 /// NM_001198897 /// NM_001198898 /// NR_037192 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202741_at AA130247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA130247 /FEA=EST /DB_XREF=gi:1691251 /DB_XREF=est:zl38g12.s1 /CLONE=IMAGE:504262 /UG=Hs.87773 protein kinase, cAMP-dependent, catalytic, beta /FL=gb:M34181.1 gb:NM_002731.1 AA130247 protein kinase, cAMP-dependent, catalytic, beta PRKACB 5567 NM_001242857 /// NM_001242858 /// NM_001242859 /// NM_001242860 /// NM_001242861 /// NM_001242862 /// NM_002731 /// NM_182948 /// NM_207578 /// XM_005271015 /// XM_005271016 /// XM_005271017 /// XM_005271018 /// XM_005271019 /// XM_005271020 /// XM_005271021 /// XM_005271022 /// XM_005271023 /// XM_006710758 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051447 // negative regulation of meiotic cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097338 // response to clozapine // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 202742_s_at NM_002731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002731.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, catalytic, beta (PRKACB), mRNA. /FEA=mRNA /GEN=PRKACB /PROD=protein kinase, cAMP-dependent, catalytic, beta /DB_XREF=gi:4506056 /UG=Hs.87773 protein kinase, cAMP-dependent, catalytic, beta /FL=gb:M34181.1 gb:NM_002731.1 NM_002731 protein kinase, cAMP-dependent, catalytic, beta PRKACB 5567 NM_001242857 /// NM_001242858 /// NM_001242859 /// NM_001242860 /// NM_001242861 /// NM_001242862 /// NM_002731 /// NM_182948 /// NM_207578 /// XM_005271015 /// XM_005271016 /// XM_005271017 /// XM_005271018 /// XM_005271019 /// XM_005271020 /// XM_005271021 /// XM_005271022 /// XM_005271023 /// XM_006710758 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051447 // negative regulation of meiotic cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097338 // response to clozapine // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 202743_at BE622627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE622627 /FEA=EST /DB_XREF=gi:9893567 /DB_XREF=est:601440792T1 /CLONE=IMAGE:3915695 /UG=Hs.88051 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) /FL=gb:D88532.1 gb:NM_003629.1 BE622627 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) PIK3R3 8503 NM_001114172 /// NM_003629 /// XM_005271290 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // traceable author statement /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation 202744_at NM_006749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006749.1 /DEF=Homo sapiens solute carrier family 20 (phosphate transporter), member 2 (SLC20A2), mRNA. /FEA=mRNA /GEN=SLC20A2 /PROD=solute carrier family 20 (phosphatetransporter), member 2 /DB_XREF=gi:5803172 /UG=Hs.10018 solute carrier family 20 (phosphate transporter), member 2 /FL=gb:L20852.1 gb:NM_006749.1 NM_006749 solute carrier family 20 (phosphate transporter), member 2 SLC20A2 6575 NM_001257180 /// NM_001257181 /// NM_006749 /// XM_005273613 /// XM_005273615 /// XM_006716390 /// XM_006716391 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 202745_at NM_005154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005154.1 /DEF=Homo sapiens ubiquitin specific protease 8 (USP8), mRNA. /FEA=mRNA /GEN=USP8 /PROD=ubiquitin specific protease 8 /DB_XREF=gi:4827053 /UG=Hs.152818 ubiquitin specific protease 8 /FL=gb:D29956.1 gb:NM_005154.1 NM_005154 ubiquitin specific peptidase 8 USP8 9101 NM_001128610 /// NM_001128611 /// NM_001283049 /// NM_005154 /// XM_006720761 /// XM_006720762 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202746_at AL021786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021786 /DEF=Human DNA sequence from PAC 696H22 on chromosome Xq21.1-21.2. Contains a mouse E25 like gene, a Kinesin like pseudogene and ESTs /FEA=mRNA /DB_XREF=gi:2853186 /UG=Hs.17109 integral membrane protein 2A /FL=gb:AF038953.1 gb:NM_004867.1 AL021786 integral membrane protein 2A ITM2A 9452 NM_001171581 /// NM_004867 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202747_s_at NM_004867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004867.1 /DEF=Homo sapiens integral membrane protein 2A (ITM2A), mRNA. /FEA=mRNA /GEN=ITM2A /PROD=integral membrane protein 2A /DB_XREF=gi:4758223 /UG=Hs.17109 integral membrane protein 2A /FL=gb:AF038953.1 gb:NM_004867.1 NM_004867 integral membrane protein 2A ITM2A 9452 NM_001171581 /// NM_004867 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202748_at NM_004120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004120.2 /DEF=Homo sapiens guanylate binding protein 2, interferon-inducible (GBP2), mRNA. /FEA=mRNA /GEN=GBP2 /PROD=guanylate binding protein 2,interferon-inducible /DB_XREF=gi:6996011 /UG=Hs.171862 guanylate binding protein 2, interferon-inducible /FL=gb:NM_004120.2 gb:M55543.1 NM_004120 guanylate binding protein 2, interferon-inducible GBP2 2634 NM_004120 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 202749_at NM_004627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004627.1 /DEF=Homo sapiens tryptophan rich basic protein (WRB), mRNA. /FEA=mRNA /GEN=WRB /PROD=tryptophan rich basic protein /DB_XREF=gi:4759325 /UG=Hs.198308 tryptophan rich basic protein /FL=gb:NM_004627.1 NM_004627 tryptophan rich basic protein WRB 7485 NM_001146218 /// NM_004627 /// XM_005261059 /// XM_005261060 /// XM_005261061 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202750_s_at AL080147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080147.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B194 (from clone DKFZp434B194); complete cds. /FEA=mRNA /GEN=DKFZp434B194 /PROD=hypothetical protein /DB_XREF=gi:5262598 /UG=Hs.20225 tuftelin-interacting protein /FL=gb:AL080147.1 gb:NM_012143.1 AL080147 tuftelin interacting protein 11 TFIP11 24144 NM_001008697 /// NM_012143 0000390 // spliceosomal complex disassembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202751_at NM_012143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012143.1 /DEF=Homo sapiens tuftelin-interacting protein (TIP39), mRNA. /FEA=mRNA /GEN=TIP39 /PROD=tuftelin-interacting protein /DB_XREF=gi:8393258 /UG=Hs.20225 tuftelin-interacting protein /FL=gb:AL080147.1 gb:NM_012143.1 NM_012143 tuftelin interacting protein 11 TFIP11 24144 NM_001008697 /// NM_012143 0000390 // spliceosomal complex disassembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202752_x_at NM_012244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012244.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (SLC7A8), mRNA. /FEA=mRNA /GEN=SLC7A8 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 8 /DB_XREF=gi:6912669 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 /FL=gb:AB037669.1 gb:AF171669.1 gb:NM_012244.1 NM_012244 solute carrier family 7 (amino acid transporter light chain, L system), member 8 SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 202753_at NM_014814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014814.1 /DEF=Homo sapiens KIAA0107 gene product (KIAA0107), mRNA. /FEA=mRNA /GEN=KIAA0107 /PROD=KIAA0107 gene product /DB_XREF=gi:7661913 /UG=Hs.23488 KIAA0107 gene product /FL=gb:BC000630.1 gb:BC000904.2 gb:D14663.1 gb:AF215935.1 gb:NM_014814.1 NM_014814 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 PSMD6 9861 NM_001271779 /// NM_001271780 /// NM_001271781 /// NM_014814 /// XM_005265618 /// XM_005265619 /// XM_006713431 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016887 // ATPase activity // non-traceable author statement 202754_at NM_015361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015361.1 /DEF=Homo sapiens KIAA0029 protein (KIAA0029), mRNA. /FEA=mRNA /GEN=KIAA0029 /PROD=KIAA0029 protein /DB_XREF=gi:7661873 /UG=Hs.268053 KIAA0029 protein /FL=gb:NM_015361.1 NM_015361 R3H domain containing 1 R3HDM1 23518 NM_001282798 /// NM_001282799 /// NM_001282800 /// NM_015361 /// XM_005263622 /// XM_005263623 /// XM_005263624 /// XM_005263626 /// XM_005263627 /// XM_005263628 /// XM_005263629 /// XM_005263631 /// XM_005263632 /// XM_005263633 /// XM_006712389 /// XM_006712390 /// XM_006712391 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202755_s_at AI354864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI354864 /FEA=EST /DB_XREF=gi:4095017 /DB_XREF=est:qt76c12.x1 /CLONE=IMAGE:1961206 /UG=Hs.2699 glypican 1 /FL=gb:NM_002081.1 AI354864 glypican 1 GPC1 2817 NM_002081 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0030200 // heparan sulfate proteoglycan catabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032288 // myelin assembly // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 202756_s_at NM_002081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002081.1 /DEF=Homo sapiens glypican 1 (GPC1), mRNA. /FEA=mRNA /GEN=GPC1 /PROD=glypican 1 precursor /DB_XREF=gi:4504080 /UG=Hs.2699 glypican 1 /FL=gb:NM_002081.1 NM_002081 glypican 1 GPC1 2817 NM_002081 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0030200 // heparan sulfate proteoglycan catabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032288 // myelin assembly // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 202757_at NM_015456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015456.1 /DEF=Homo sapiens DKFZP586B0519 protein (DKFZP586B0519), mRNA. /FEA=mRNA /GEN=DKFZP586B0519 /PROD=DKFZP586B0519 protein /DB_XREF=gi:7661663 /UG=Hs.27633 DKFZP586B0519 protein /FL=gb:AL050280.1 gb:NM_015456.1 NM_015456 negative elongation factor complex member B NELFB 25920 NM_015456 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202758_s_at NM_003721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003721.1 /DEF=Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), mRNA. /FEA=mRNA /GEN=RFXANK /PROD=regulatory factor X-associatedankyrin-containing protein /DB_XREF=gi:4506498 /UG=Hs.296776 regulatory factor X-associated ankyrin-containing protein /FL=gb:AF094760.1 gb:AF105427.1 gb:NM_003721.1 gb:AF077196.1 NM_003721 regulatory factor X-associated ankyrin-containing protein RFXANK 8625 NM_001278727 /// NM_001278728 /// NM_003721 /// NM_134440 /// XM_005260134 /// XM_005260135 /// XM_005260136 /// XM_005260137 /// XM_006722930 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation 202759_s_at BE879367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE879367 /FEA=EST /DB_XREF=gi:10328143 /DB_XREF=est:601484628F1 /CLONE=IMAGE:3887262 /UG=Hs.42322 A kinase (PRKA) anchor protein 2 /FL=gb:AB023137.1 gb:NM_007203.1 BE879367 A kinase (PRKA) anchor protein 2 /// PALM2-AKAP2 readthrough AKAP2 /// PALM2-AKAP2 11217 /// 445815 NM_001004065 /// NM_001136562 /// NM_001198656 /// NM_007203 /// NM_147150 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 202760_s_at NM_007203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007203.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 2 (AKAP2), mRNA. /FEA=mRNA /GEN=AKAP2 /PROD=A kinase (PRKA) anchor protein 2 /DB_XREF=gi:6005708 /UG=Hs.42322 A kinase (PRKA) anchor protein 2 /FL=gb:AB023137.1 gb:NM_007203.1 NM_007203 A kinase (PRKA) anchor protein 2 /// PALM2-AKAP2 readthrough AKAP2 /// PALM2-AKAP2 11217 /// 445815 NM_001004065 /// NM_001136562 /// NM_001198656 /// NM_007203 /// NM_147150 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 202761_s_at NM_015180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015180.1 /DEF=Homo sapiens synaptic nuclei expressed gene 2; KIAA1011 protein (KIAA1011), mRNA. /FEA=mRNA /GEN=KIAA1011 /PROD=KIAA1011 protein /DB_XREF=gi:11056019 /UG=Hs.57749 synaptic nuclei expressed gene 2; KIAA1011 protein /FL=gb:NM_015180.1 gb:AL080133.1 NM_015180 spectrin repeat containing, nuclear envelope 2 SYNE2 23224 NM_015180 /// NM_182910 /// NM_182912 /// NM_182913 /// NM_182914 /// XM_005267454 /// XM_005267455 /// XM_005267456 /// XM_005267457 /// XM_005267458 /// XM_005267459 /// XM_005267460 /// XM_006720084 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from mutant phenotype /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031022 // nuclear migration along microfilament // inferred from sequence or structural similarity /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from mutant phenotype /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0031981 // nuclear lumen // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202762_at AL049383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049383.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L0218 (from clone DKFZp586L0218). /FEA=mRNA /DB_XREF=gi:4500172 /UG=Hs.58617 Rho-associated, coiled-coil containing protein kinase 2 /FL=gb:AB014519.1 gb:NM_004850.2 AL049383 Rho-associated, coiled-coil containing protein kinase 2 ROCK2 9475 NM_004850 /// XM_005246190 0000910 // cytokinesis // non-traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006939 // smooth muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0010825 // positive regulation of centrosome duplication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // traceable author statement /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045616 // regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 2000114 // regulation of establishment of cell polarity // traceable author statement /// 2000145 // regulation of cell motility // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202763_at NM_004346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004346.1 /DEF=Homo sapiens caspase 3, apoptosis-related cysteine protease (CASP3), mRNA. /FEA=mRNA /GEN=CASP3 /PROD=caspase 3, apoptosis-related cysteine protease /DB_XREF=gi:4757911 /UG=Hs.74552 caspase 3, apoptosis-related cysteine protease /FL=gb:NM_004346.1 gb:U13737.1 gb:U13738.1 gb:U26943.1 NM_004346 caspase 3, apoptosis-related cysteine peptidase CASP3 836 NM_004346 /// NM_032991 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030182 // neuron differentiation // not recorded /// 0030198 // extracellular matrix organization // traceable author statement /// 0030216 // keratinocyte differentiation // not recorded /// 0030218 // erythrocyte differentiation // inferred from direct assay /// 0030218 // erythrocyte differentiation // traceable author statement /// 0030220 // platelet formation // traceable author statement /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from mutant phenotype /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from genetic interaction /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0046007 // negative regulation of activated T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0097200 // cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from mutant phenotype 202764_at NM_003156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003156.1 /DEF=Homo sapiens stromal interaction molecule 1 (STIM1), mRNA. /FEA=mRNA /GEN=STIM1 /PROD=stromal interaction molecule 1 /DB_XREF=gi:4507268 /UG=Hs.74597 stromal interaction molecule 1 /FL=gb:U52426.1 gb:NM_003156.1 NM_003156 stromal interaction molecule 1 STIM1 6786 NM_001277961 /// NM_001277962 /// NM_003156 0002115 // store-operated calcium entry // inferred from electronic annotation /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 202765_s_at AI264196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI264196 /FEA=EST /DB_XREF=gi:3872399 /DB_XREF=est:qi20h04.x1 /CLONE=IMAGE:1857079 /UG=Hs.750 fibrillin 1 (Marfan syndrome) /FL=gb:L13923.1 gb:NM_000138.1 AI264196 fibrillin 1 FBN1 2200 NM_000138 0001501 // skeletal system development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202766_s_at NM_000138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000138.1 /DEF=Homo sapiens fibrillin 1 (Marfan syndrome) (FBN1), mRNA. /FEA=mRNA /GEN=FBN1 /PROD=fibrillin 1 /DB_XREF=gi:4557590 /UG=Hs.750 fibrillin 1 (Marfan syndrome) /FL=gb:L13923.1 gb:NM_000138.1 NM_000138 fibrillin 1 FBN1 2200 NM_000138 0001501 // skeletal system development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202767_at NM_001610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001610.1 /DEF=Homo sapiens acid phosphatase 2, lysosomal (ACP2), mRNA. /FEA=mRNA /GEN=ACP2 /PROD=lysosomal acid phosphatase 2 precursor /DB_XREF=gi:4557009 /UG=Hs.75589 acid phosphatase 2, lysosomal /FL=gb:BC003160.1 gb:NM_001610.1 NM_001610 acid phosphatase 2, lysosomal ACP2 53 NM_001131064 /// NM_001610 /// XM_005252984 /// XM_005252985 /// XR_242812 0001501 // skeletal system development // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202768_at NM_006732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006732.1 /DEF=Homo sapiens FBJ murine osteosarcoma viral oncogene homolog B (FOSB), mRNA. /FEA=mRNA /GEN=FOSB /PROD=FBJ murine osteosarcoma viral oncogene homologB /DB_XREF=gi:5803016 /UG=Hs.75678 FBJ murine osteosarcoma viral oncogene homolog B /FL=gb:L49169.1 gb:NM_006732.1 NM_006732 FBJ murine osteosarcoma viral oncogene homolog B FOSB 2354 NM_001114171 /// NM_006732 /// XM_005258691 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202769_at AW134535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134535 /FEA=EST /DB_XREF=gi:6138088 /DB_XREF=est:UI-H-BI1-abv-g-06-0-UI.s1 /CLONE=IMAGE:2713163 /UG=Hs.79069 cyclin G2 /FL=gb:U47414.1 gb:NM_004354.1 AW134535 cyclin G2 CCNG2 901 NM_004354 0000075 // cell cycle checkpoint // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 202770_s_at NM_004354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004354.1 /DEF=Homo sapiens cyclin G2 (CCNG2), mRNA. /FEA=mRNA /GEN=CCNG2 /PROD=cyclin G2 /DB_XREF=gi:4757935 /UG=Hs.79069 cyclin G2 /FL=gb:U47414.1 gb:NM_004354.1 NM_004354 cyclin G2 CCNG2 901 NM_004354 0000075 // cell cycle checkpoint // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 202771_at NM_014745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014745.1 /DEF=Homo sapiens KIAA0233 gene product (KIAA0233), mRNA. /FEA=mRNA /GEN=KIAA0233 /PROD=KIAA0233 gene product /DB_XREF=gi:7662013 /UG=Hs.79077 KIAA0233 gene product /FL=gb:D87071.1 gb:NM_014745.1 NM_014745 piezo-type mechanosensitive ion channel component 1 PIEZO1 9780 NM_001142864 /// XM_006721353 /// XM_006721354 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0033625 // positive regulation of integrin activation // inferred from mutant phenotype /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0008381 // mechanically-gated ion channel activity // inferred from electronic annotation 202772_at NM_000191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000191.1 /DEF=Homo sapiens 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) (HMGCL), mRNA. /FEA=mRNA /GEN=HMGCL /PROD=3-hydroxymethyl-3-methylglutaryl-Coenzyme Alyase (hydroxymethylglutaricaciduria) /DB_XREF=gi:4504426 /UG=Hs.831 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) /FL=gb:L07033.1 gb:NM_000191.1 NM_000191 3-hydroxymethyl-3-methylglutaryl-CoA lyase HMGCL 3155 NM_000191 /// NM_001166059 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006552 // leucine catabolic process // non-traceable author statement /// 0006637 // acyl-CoA metabolic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // inferred from direct assay /// 0046951 // ketone body biosynthetic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0070542 // response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005777 // peroxisome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0004419 // hydroxymethylglutaryl-CoA lyase activity // inferred from direct assay /// 0004419 // hydroxymethylglutaryl-CoA lyase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from direct assay 202773_s_at AI023864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI023864 /FEA=EST /DB_XREF=gi:3238908 /DB_XREF=est:ow69a07.s1 /CLONE=IMAGE:1652052 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1 AI023864 splicing factor, suppressor of white-apricot family SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202774_s_at AI871457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871457 /FEA=EST /DB_XREF=gi:5545506 /DB_XREF=est:wl67c04.x1 /CLONE=IMAGE:2429958 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1 AI871457 splicing factor, suppressor of white-apricot family SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202775_s_at NM_004592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004592.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) (SFRS8), mRNA. /FEA=mRNA /GEN=SFRS8 /PROD=splicing factor, arginineserine-rich 8(suppressor-of-white-apricot, Drosophila homolog) /DB_XREF=gi:4759101 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1 NM_004592 splicing factor, suppressor of white-apricot family SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202776_at NM_014597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014597.1 /DEF=Homo sapiens acidic 82 kDa protein mRNA (HSU15552), mRNA. /FEA=mRNA /GEN=HSU15552 /PROD=acidic 82 kDa protein mRNA /DB_XREF=gi:7657203 /UG=Hs.85769 acidic 82 kDa protein mRNA /FL=gb:U15552.1 gb:NM_014597.1 NM_014597 deoxynucleotidyltransferase, terminal, interacting protein 2 DNTTIP2 30836 NM_014597 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202777_at NM_007373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007373.1 /DEF=Homo sapiens suppressor of clear, C. elegans, homolog of (SHOC2), mRNA. /FEA=mRNA /GEN=SHOC2 /PROD=suppressor of clear, C. elegans, homolog of /DB_XREF=gi:6677944 /UG=Hs.104315 soc-2 (suppressor of clear, C.elegans) homolog /FL=gb:AF068920.1 gb:AF054828.1 gb:AB020669.1 gb:NM_007373.1 NM_007373 soc-2 suppressor of clear homolog (C. elegans) SHOC2 8036 NM_001269039 /// NM_007373 0007265 // Ras protein signal transduction // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // non-traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement 0000164 // protein phosphatase type 1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // traceable author statement /// 0019903 // protein phosphatase binding // inferred from direct assay 202778_s_at NM_003453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003453.1 /DEF=Homo sapiens zinc finger protein 198 (ZNF198), mRNA. /FEA=mRNA /GEN=ZNF198 /PROD=zinc finger protein 198 /DB_XREF=gi:4508010 /UG=Hs.109526 zinc finger protein 198 /FL=gb:AF035374.1 gb:AF060181.1 gb:NM_003453.1 NM_003453 zinc finger, MYM-type 2 ZMYM2 7750 NM_001190964 /// NM_001190965 /// NM_003453 /// NM_197968 /// XM_005266517 /// XM_005266518 /// XM_005266519 /// XM_005266520 /// XM_005266521 /// XM_006719864 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0008270 // zinc ion binding // non-traceable author statement /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202779_s_at NM_014501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014501.1 /DEF=Homo sapiens ubiquitin carrier protein (E2-EPF), mRNA. /FEA=mRNA /GEN=E2-EPF /PROD=ubiquitin carrier protein /DB_XREF=gi:7657045 /UG=Hs.174070 ubiquitin carrier protein /FL=gb:M91670.1 gb:NM_014501.1 NM_014501 ubiquitin-conjugating enzyme E2S UBE2S 27338 NM_014501 0006464 // cellular protein modification process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from direct assay /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0010994 // free ubiquitin chain polymerization // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0005680 // anaphase-promoting complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 202780_at NM_000436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000436.1 /DEF=Homo sapiens 3-oxoacid CoA transferase (OXCT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OXCT /PROD=3-oxoacid CoA transferase precursor /DB_XREF=gi:4557816 /UG=Hs.177584 3-oxoacid CoA transferase /FL=gb:U62961.1 gb:NM_000436.1 NM_000436 3-oxoacid CoA transferase 1 OXCT1 5019 NM_000436 /// XR_427658 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0042182 // ketone catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046950 // cellular ketone body metabolic process // inferred from mutant phenotype /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046952 // ketone body catabolic process // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0008260 // 3-oxoacid CoA-transferase activity // inferred from mutant phenotype /// 0008260 // 3-oxoacid CoA-transferase activity // traceable author statement /// 0008410 // CoA-transferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement 202781_s_at AI806031 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806031 /FEA=EST /DB_XREF=gi:5392597 /DB_XREF=est:te53d09.x1 /CLONE=IMAGE:2090417 /UG=Hs.178347 SKIP for skeletal muscle and kidney enriched inositol phosphatase /FL=gb:AB036829.1 gb:NM_016532.1 AI806031 inositol polyphosphate-5-phosphatase K INPP5K 51763 NM_001135642 /// NM_016532 /// NM_130766 /// XM_005256683 /// XM_005256685 /// XM_005256686 /// XM_006721545 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005979 // regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from sequence or structural similarity /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035305 // negative regulation of dephosphorylation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0072661 // protein targeting to plasma membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 0097178 // ruffle assembly // inferred from direct assay /// 2000466 // negative regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2001153 // positive regulation of renal water transport // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016312 // inositol bisphosphate phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034485 // phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from direct assay /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from mutant phenotype /// 0042577 // lipid phosphatase activity // non-traceable author statement /// 0046030 // inositol trisphosphate phosphatase activity // inferred from direct assay /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation 202782_s_at NM_016532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016532.1 /DEF=Homo sapiens SKIP for skeletal muscle and kidney enriched inositol phosphatase (LOC51763), mRNA. /FEA=mRNA /GEN=LOC51763 /PROD=SKIP for skeletal muscle and kidney enrichedinositol phosphatase /DB_XREF=gi:7706564 /UG=Hs.178347 SKIP for skeletal muscle and kidney enriched inositol phosphatase /FL=gb:AB036829.1 gb:NM_016532.1 NM_016532 inositol polyphosphate-5-phosphatase K INPP5K 51763 NM_001135642 /// NM_016532 /// NM_130766 /// XM_005256683 /// XM_005256685 /// XM_005256686 /// XM_006721545 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005979 // regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from sequence or structural similarity /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035305 // negative regulation of dephosphorylation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0072661 // protein targeting to plasma membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 0097178 // ruffle assembly // inferred from direct assay /// 2000466 // negative regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2001153 // positive regulation of renal water transport // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016312 // inositol bisphosphate phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034485 // phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from direct assay /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from mutant phenotype /// 0042577 // lipid phosphatase activity // non-traceable author statement /// 0046030 // inositol trisphosphate phosphatase activity // inferred from direct assay /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation 202783_at U40490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U40490.1 /DEF=Human nicotinamide nucleotide transhydrogenase mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=nicotinamide nucleotide transhydrogenase /DB_XREF=gi:1110519 /UG=Hs.18136 nicotinamide nucleotide transhydrogenase /FL=gb:U40490.1 gb:NM_012343.1 U40490 nicotinamide nucleotide transhydrogenase NNT 23530 NM_012343 /// NM_182977 /// XM_005248274 /// XM_005248275 /// XM_006714461 0006099 // tricarboxylic acid cycle // traceable author statement /// 0015992 // proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003957 // NAD(P)+ transhydrogenase (B-specific) activity // traceable author statement /// 0008746 // NAD(P)+ transhydrogenase activity // not recorded /// 0008750 // NAD(P)+ transhydrogenase (AB-specific) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0051287 // NAD binding // traceable author statement 202784_s_at NM_012343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012343.1 /DEF=Homo sapiens nicotinamide nucleotide transhydrogenase (NNT), mRNA. /FEA=mRNA /GEN=NNT /PROD=nicotinamide nucleotide transhydrogenase /DB_XREF=gi:6912535 /UG=Hs.18136 nicotinamide nucleotide transhydrogenase /FL=gb:U40490.1 gb:NM_012343.1 NM_012343 nicotinamide nucleotide transhydrogenase NNT 23530 NM_012343 /// NM_182977 /// XM_005248274 /// XM_005248275 /// XM_006714461 0006099 // tricarboxylic acid cycle // traceable author statement /// 0015992 // proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003957 // NAD(P)+ transhydrogenase (B-specific) activity // traceable author statement /// 0008746 // NAD(P)+ transhydrogenase activity // not recorded /// 0008750 // NAD(P)+ transhydrogenase (AB-specific) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0051287 // NAD binding // traceable author statement 202785_at NM_005001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005001.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (14.5kD, B14.5a) (NDUFA7), mRNA. /FEA=mRNA /GEN=NDUFA7 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 7 (14.5kD, B14.5a) /DB_XREF=gi:4826849 /UG=Hs.19561 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (14.5kD, B14.5a) /FL=gb:BC003102.1 gb:AF054178.1 gb:AF050637.1 gb:NM_005001.1 NM_005001 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa NDUFA7 4701 NM_005001 /// XR_246670 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042773 // ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202786_at NM_013233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013233.1 /DEF=Homo sapiens Ste-20 related kinase (SPAK), mRNA. /FEA=mRNA /GEN=SPAK /PROD=Ste-20 related kinase /DB_XREF=gi:7019542 /UG=Hs.199263 Ste-20 related kinase /FL=gb:AF017635.1 gb:AF099989.1 gb:AF030403.1 gb:NM_013233.1 NM_013233 serine threonine kinase 39 STK39 27347 NM_013233 /// XM_005246465 /// XM_005246466 0006468 // protein phosphorylation // non-traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0071476 // cellular hypotonic response // inferred by curator /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 2000681 // negative regulation of rubidium ion transport // inferred from direct assay /// 2000687 // negative regulation of rubidium ion transmembrane transporter activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 202787_s_at U43784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43784.1 /DEF=Human mitogen activated protein kinase activated protein kinase-3 mRNA, complete cds. /FEA=mRNA /PROD=mitogen activated protein kinase activatedprotein kinase-3 /DB_XREF=gi:1256004 /UG=Hs.227789 mitogen-activated protein kinase-activated protein kinase 3 /FL=gb:U09578.1 gb:U43784.1 gb:BC001662.1 gb:NM_004635.1 U43784 mitogen-activated protein kinase-activated protein kinase 3 MAPKAPK3 7867 NM_001243925 /// NM_001243926 /// NM_004635 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202788_at NM_004635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004635.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3), mRNA. /FEA=mRNA /GEN=MAPKAPK3 /PROD=mitogen-activated protein kinase-activatedprotein kinase 3 /DB_XREF=gi:4758699 /UG=Hs.227789 mitogen-activated protein kinase-activated protein kinase 3 /FL=gb:U09578.1 gb:U43784.1 gb:BC001662.1 gb:NM_004635.1 NM_004635 mitogen-activated protein kinase-activated protein kinase 3 MAPKAPK3 7867 NM_001243925 /// NM_001243926 /// NM_004635 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 202789_at AL022394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022394 /DEF=Human DNA sequence from clone RP3-511B24 on chromosome 20q11.2-12. Contains the 3 end of the TOP1 gene for topoisomerase (DNA) I, the PLCG1 gene for phospholipase C gamma 1, gene KIAA0395 for a possible homeobox protein, a 60S Ribosomal Protein L... /FEA=mRNA_1 /DB_XREF=gi:11345540 /UG=Hs.268177 phospholipase C, gamma 1 (formerly subtype 148) /FL=gb:M34667.1 gb:NM_002660.1 AL022394 phospholipase C, gamma 1 PLCG1 5335 NM_002660 /// NM_182811 /// XM_005260438 /// XR_244143 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202790_at NM_001307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001307.1 /DEF=Homo sapiens claudin 7 (CLDN7), mRNA. /FEA=mRNA /GEN=CLDN7 /PROD=claudin 7 /DB_XREF=gi:10835007 /UG=Hs.278562 claudin 7 /FL=gb:NM_001307.1 gb:BC001055.1 NM_001307 claudin 7 CLDN7 1366 NM_001185022 /// NM_001185023 /// NM_001307 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity 202791_s_at AK022669 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022669.1 /DEF=Homo sapiens cDNA FLJ12607 fis, clone NT2RM4001489, highly similar to Homo sapiens mRNA for KIAA0685 protein. /FEA=mRNA /DB_XREF=gi:10434196 /UG=Hs.296406 KIAA0685 gene product /FL=gb:AB014585.1 gb:NM_014678.1 AK022669 protein phosphatase 6, regulatory subunit 2 PPP6R2 9701 NM_001242898 /// NM_001242899 /// NM_001242900 /// NM_014678 /// XM_005261956 /// XM_005261957 /// XM_005261958 /// XM_005261959 /// XM_005261960 /// XM_006724428 /// XM_006724429 /// XM_006724430 /// XM_006724431 /// XM_006724432 /// XM_006724433 /// XM_006724434 /// XM_006724435 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202792_s_at NM_014678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014678.1 /DEF=Homo sapiens KIAA0685 gene product (KIAA0685), mRNA. /FEA=mRNA /GEN=KIAA0685 /PROD=KIAA0685 gene product /DB_XREF=gi:7662251 /UG=Hs.296406 KIAA0685 gene product /FL=gb:AB014585.1 gb:NM_014678.1 NM_014678 protein phosphatase 6, regulatory subunit 2 PPP6R2 9701 NM_001242898 /// NM_001242899 /// NM_001242900 /// NM_014678 /// XM_005261956 /// XM_005261957 /// XM_005261958 /// XM_005261959 /// XM_005261960 /// XM_006724428 /// XM_006724429 /// XM_006724430 /// XM_006724431 /// XM_006724432 /// XM_006724433 /// XM_006724434 /// XM_006724435 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202793_at NM_005768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005768.2 /DEF=Homo sapiens putative protein similar to nessy (Drosophila) (C3F), mRNA. /FEA=mRNA /GEN=C3F /PROD=putative protein similar to nessy (Drosophila) /DB_XREF=gi:5579449 /UG=Hs.300423 putative protein similar to nessy (Drosophila) /FL=gb:BC000664.1 gb:U72515.1 gb:NM_005768.2 NM_005768 lysophosphatidylcholine acyltransferase 3 LPCAT3 10162 NM_005768 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0097006 // regulation of plasma lipoprotein particle levels // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from mutant phenotype 202794_at NM_002194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002194.2 /DEF=Homo sapiens inositol polyphosphate-1-phosphatase (INPP1), mRNA. /FEA=mRNA /GEN=INPP1 /PROD=inositol polyphosphate-1-phosphatase /DB_XREF=gi:4755138 /UG=Hs.32309 inositol polyphosphate-1-phosphatase /FL=gb:L08488.1 gb:NM_002194.2 NM_002194 inositol polyphosphate-1-phosphatase INPP1 3628 NM_001128928 /// NM_002194 /// XM_005246532 /// XM_006712498 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004441 // inositol-1,4-bisphosphate 1-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052829 // inositol-1,3,4-trisphosphate 1-phosphatase activity // traceable author statement 202795_x_at NM_007032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007032.1 /DEF=Homo sapiens putative nuclear protein (HRIHFB2122), mRNA. /FEA=mRNA /GEN=HRIHFB2122 /PROD=putative nuclear protein /DB_XREF=gi:10334853 /UG=Hs.40342 putative nuclear protein /FL=gb:NM_007032.1 NM_007032 TRIO and F-actin binding protein TRIOBP 11078 NM_001039141 /// NM_007032 /// NM_138632 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030047 // actin modification // non-traceable author statement /// 0051016 // barbed-end actin filament capping // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0030496 // midbody // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0045159 // myosin II binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from direct assay 202796_at NM_007286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007286.1 /DEF=Homo sapiens synaptopodin (KIAA1029), mRNA. /FEA=mRNA /GEN=KIAA1029 /PROD=synaptopodin /DB_XREF=gi:6005797 /UG=Hs.5307 synaptopodin /FL=gb:AB028952.1 gb:NM_007286.1 NM_007286 synaptopodin SYNPO 11346 NM_001109974 /// NM_001166208 /// NM_001166209 /// NM_007286 /// XM_005268369 /// XM_005268370 /// XM_005268371 /// XM_006714755 0032233 // positive regulation of actin filament bundle assembly // inferred from electronic annotation /// 0032233 // positive regulation of actin filament bundle assembly // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // inferred from electronic annotation /// 0051492 // regulation of stress fiber assembly // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202797_at NM_014016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014016.1 /DEF=Homo sapiens KIAA0851 protein (KIAA0851), mRNA. /FEA=mRNA /GEN=KIAA0851 /PROD=KIAA0851 protein /DB_XREF=gi:7662337 /UG=Hs.5867 KIAA0851 protein /FL=gb:AB020658.1 gb:AL136831.1 gb:NM_014016.1 NM_014016 SAC1 suppressor of actin mutations 1-like (yeast) SACM1L 22908 NM_014016 /// XR_427259 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0034593 // phosphatidylinositol bisphosphate phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0043812 // phosphatidylinositol-4-phosphate phosphatase activity // inferred from electronic annotation 202798_at NM_006323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006323.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member B (SEC24B), mRNA. /FEA=mRNA /GEN=SEC24B /PROD=SEC24 (S. cerevisiae) related gene family,member B /DB_XREF=gi:5454045 /UG=Hs.7239 SEC24 (S. cerevisiae) related gene family, member B /FL=gb:NM_006323.1 NM_006323 SEC24 family member B SEC24B 10427 NM_001042734 /// NM_006323 /// XM_005262688 /// XM_005262689 /// XM_005262691 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 202799_at NM_006012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006012.1 /DEF=Homo sapiens ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli) homolog (CLPP), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CLPP /PROD=endopeptidase Clp precursor /DB_XREF=gi:5174418 /UG=Hs.74362 ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli) homolog /FL=gb:BC002956.1 gb:NM_006012.1 NM_006012 caseinolytic mitochondrial matrix peptidase proteolytic subunit CLPP 8192 NM_006012 0006508 // proteolysis // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0009368 // endopeptidase Clp complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 202800_at NM_004172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004172.1 /DEF=Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC1A3 /PROD=solute carrier family 1 (glial high affinityglutamate transporter), member 3 /DB_XREF=gi:4759125 /UG=Hs.75379 solute carrier family 1 (glial high affinity glutamate transporter), member 3 /FL=gb:D26443.1 gb:NM_004172.1 gb:U03504.1 NM_004172 solute carrier family 1 (glial high affinity glutamate transporter), member 3 SLC1A3 6507 NM_001166695 /// NM_001166696 /// NM_001289939 /// NM_001289940 /// NM_004172 /// XM_005248342 /// XM_006714488 0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009449 // gamma-aminobutyric acid biosynthetic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043205 // fibril // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005314 // high-affinity glutamate transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 202801_at NM_002730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002730.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), mRNA. /FEA=mRNA /GEN=PRKACA /PROD=protein kinase, cAMP-dependent, catalytic,alpha /DB_XREF=gi:4506054 /UG=Hs.77271 protein kinase, cAMP-dependent, catalytic, alpha /FL=gb:NM_002730.1 NM_002730 protein kinase, cAMP-dependent, catalytic, alpha PRKACA 5566 NM_002730 /// NM_207518 /// XM_005259984 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0002027 // regulation of heart rate // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // traceable author statement /// 0043393 // regulation of protein binding // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from direct assay /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement /// 2000810 // regulation of tight junction assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0034704 // calcium channel complex // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097225 // sperm midpiece // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004691 // cAMP-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from physical interaction 202802_at NM_001930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001930.2 /DEF=Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 1, mRNA. /FEA=mRNA /GEN=DHPS /PROD=deoxyhypusine synthase isoform a /DB_XREF=gi:7108341 /UG=Hs.79064 deoxyhypusine synthase /FL=gb:U40579.1 gb:BC000333.1 gb:U32178.1 gb:U79262.1 gb:NM_001930.2 gb:L39068.1 NM_001930 deoxyhypusine synthase DHPS 1725 NM_001206974 /// NM_001930 /// NM_013406 /// NM_013407 /// NR_038192 0006412 // translation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050983 // deoxyhypusine biosynthetic process from spermidine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0034038 // deoxyhypusine synthase activity // traceable author statement 202803_s_at NM_000211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000211.1 /DEF=Homo sapiens integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) (ITGB2), mRNA. /FEA=mRNA /GEN=ITGB2 /PROD=integrin beta chain, beta 2 precursor /DB_XREF=gi:4557885 /UG=Hs.83968 integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) /FL=gb:NM_000211.1 NM_000211 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) ITGB2 3689 NM_000211 /// NM_001127491 /// XM_006724001 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202804_at AI539710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI539710 /FEA=EST /DB_XREF=gi:4453845 /DB_XREF=est:tp77b05.x1 /CLONE=IMAGE:2205297 /UG=Hs.89433 ATP-binding cassette, sub-family C (CFTRMRP), member 1 /FL=gb:L05628.1 gb:NM_004996.2 AI539710 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 ABCC1 4363 NM_004996 /// NM_019862 /// NM_019898 /// NM_019899 /// NM_019900 /// NM_019901 /// NM_019902 /// XM_005255327 /// XM_005255328 /// XM_005255329 /// XM_006720884 /// XM_006720885 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 202805_s_at NM_004996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004996.2 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 1 (ABCC1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCC1 /PROD=ATP-binding cassette, sub-family C, member 1,isoform 1 /DB_XREF=gi:9955961 /UG=Hs.89433 ATP-binding cassette, sub-family C (CFTRMRP), member 1 /FL=gb:L05628.1 gb:NM_004996.2 NM_004996 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 ABCC1 4363 NM_004996 /// NM_019862 /// NM_019898 /// NM_019899 /// NM_019900 /// NM_019901 /// NM_019902 /// XM_005255327 /// XM_005255328 /// XM_005255329 /// XM_006720884 /// XM_006720885 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 202806_at NM_004395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004395.1 /DEF=Homo sapiens drebrin 1 (DBN1), mRNA. /FEA=mRNA /GEN=DBN1 /PROD=drebrin 1 /DB_XREF=gi:4758123 /UG=Hs.89434 drebrin 1 /FL=gb:BC000283.1 gb:U00802.1 gb:NM_004395.1 gb:D17530.1 NM_004395 drebrin 1 DBN1 1627 NM_004395 /// NM_080881 /// XM_005265827 /// XM_005265828 /// XM_005265829 /// XM_006714826 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032507 // maintenance of protein location in cell // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // non-traceable author statement /// 0048699 // generation of neurons // inferred from electronic annotation /// 0050773 // regulation of dendrite development // non-traceable author statement /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // non-traceable author statement /// 0042641 // actomyosin // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from sequence or structural similarity 202807_s_at NM_005488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005488.1 /DEF=Homo sapiens target of myb1 (chicken) homolog (TOM1), mRNA. /FEA=mRNA /GEN=TOM1 /PROD=target of myb1 (chicken) homolog /DB_XREF=gi:4885636 /UG=Hs.9482 target of myb1 (chicken) homolog /FL=gb:NM_005488.1 NM_005488 target of myb1 (chicken) TOM1 10043 NM_001135729 /// NM_001135730 /// NM_001135732 /// NM_005488 /// NR_024194 /// NR_024195 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // non-traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0016197 // endosomal transport // non-traceable author statement /// 0016197 // endosomal transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from direct assay 202808_at AK000161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000161.1 /DEF=Homo sapiens cDNA FLJ20154 fis, clone COL08740. /FEA=mRNA /DB_XREF=gi:7020067 /UG=Hs.10346 hypothetical protein FLJ20154 /FL=gb:NM_017787.1 AK000161 WW domain binding protein 1-like WBP1L 54838 NM_001083913 /// NM_017787 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202809_s_at NM_023015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023015.1 /DEF=Homo sapiens hypothetical protein FLJ21919 (FLJ21919), mRNA. /FEA=mRNA /GEN=FLJ21919 /PROD=hypothetical protein FLJ21919 /DB_XREF=gi:12711679 /UG=Hs.105894 hypothetical protein FLJ21919 /FL=gb:NM_023015.1 NM_023015 integrator complex subunit 3 INTS3 65123 NM_023015 /// XM_005245459 /// XM_005245461 /// XM_005276735 /// XM_005276737 /// XM_006711490 /// XM_006711491 /// XM_006726204 /// XM_006726205 /// XR_241094 /// XR_254195 0006281 // DNA repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay /// 0070876 // SOSS complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202810_at NM_004147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004147.1 /DEF=Homo sapiens developmentally regulated GTP-binding protein 1 (DRG1), mRNA. /FEA=mRNA /GEN=DRG1 /PROD=developmentally regulated GTP-binding protein 1 /DB_XREF=gi:4758795 /UG=Hs.115242 developmentally regulated GTP-binding protein 1 /FL=gb:AF078103.1 gb:NM_004147.1 NM_004147 developmentally regulated GTP binding protein 1 DRG1 4733 NM_004147 0006351 // transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202811_at NM_006463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006463.1 /DEF=Homo sapiens associated molecule with the SH3 domain of STAM (AMSH), mRNA. /FEA=mRNA /GEN=AMSH /PROD=associated molecule with the SH3 domain of STAM /DB_XREF=gi:5453544 /UG=Hs.12479 associated molecule with the SH3 domain of STAM /FL=gb:U73522.1 gb:NM_006463.1 NM_006463 STAM binding protein STAMBP 10617 NM_006463 /// NM_201647 /// NM_213622 /// XM_005264088 /// XM_005264091 /// XM_006711920 /// XM_006711921 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202812_at NM_000152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000152.2 /DEF=Homo sapiens glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) (GAA), mRNA. /FEA=mRNA /GEN=GAA /PROD=acid alpha-glucosidase preproprotein /DB_XREF=gi:11496988 /UG=Hs.1437 glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) /FL=gb:NM_000152.2 gb:M34424.1 NM_000152 glucosidase, alpha; acid GAA 2548 NM_000152 /// NM_001079803 /// NM_001079804 /// XM_005257193 /// XM_005257194 0000023 // maltose metabolic process // inferred by curator /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002086 // diaphragm contraction // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // inferred from direct assay /// 0005985 // sucrose metabolic process // inferred by curator /// 0006006 // glucose metabolic process // inferred by curator /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0043181 // vacuolar sequestering // inferred from mutant phenotype /// 0043587 // tongue morphogenesis // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004558 // alpha-glucosidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032450 // maltose alpha-glucosidase activity // inferred from electronic annotation 202813_at NM_005646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005646.1 /DEF=Homo sapiens TAR (HIV) RNA-binding protein 1 (TARBP1), mRNA. /FEA=mRNA /GEN=TARBP1 /PROD=TAR (HIV) RNA-binding protein 1 /DB_XREF=gi:5032156 /UG=Hs.151518 TAR (HIV) RNA-binding protein 1 /FL=gb:U38847.1 gb:NM_005646.1 NM_005646 TAR (HIV-1) RNA binding protein 1 TARBP1 6894 NM_005646 /// XM_005273234 /// XM_006711812 0001510 // RNA methylation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202814_s_at AW193511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW193511 /FEA=EST /DB_XREF=gi:6472210 /DB_XREF=est:xm17b10.x1 /CLONE=IMAGE:2684443 /UG=Hs.15299 HMBA-inducible /FL=gb:AB021179.1 gb:NM_006460.1 AW193511 hexamethylene bis-acetamide inducible 1 HEXIM1 10614 NM_006460 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from direct assay 202815_s_at NM_006460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006460.1 /DEF=Homo sapiens HMBA-inducible (HIS1), mRNA. /FEA=mRNA /GEN=HIS1 /PROD=HMBA-inducible /DB_XREF=gi:5453681 /UG=Hs.15299 HMBA-inducible /FL=gb:AB021179.1 gb:NM_006460.1 NM_006460 hexamethylene bis-acetamide inducible 1 HEXIM1 10614 NM_006460 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from direct assay 202816_s_at AW292882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW292882 /FEA=EST /DB_XREF=gi:6699518 /DB_XREF=est:UI-H-BW0-aif-g-06-0-UI.s1 /CLONE=IMAGE:2729267 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome /FL=gb:NM_005637.1 AW292882 synovial sarcoma translocation, chromosome 18 SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 202817_s_at NM_005637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005637.1 /DEF=Homo sapiens synovial sarcoma, translocated to X chromosome (SSXT), mRNA. /FEA=mRNA /GEN=SSXT /PROD=synovial sarcoma, translocated to X chromosome /DB_XREF=gi:5032124 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome /FL=gb:NM_005637.1 NM_005637 synovial sarcoma translocation, chromosome 18 SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 202818_s_at AI344128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI344128 /FEA=EST /DB_XREF=gi:4081334 /DB_XREF=est:tc02c08.x1 /CLONE=IMAGE:2062670 /UG=Hs.155202 transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) /FL=gb:BC002883.1 gb:NM_003198.1 gb:L47345.1 AI344128 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) TCEB3 6924 NM_003198 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202819_s_at NM_003198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003198.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) (TCEB3), mRNA. /FEA=mRNA /GEN=TCEB3 /PROD=elongin A /DB_XREF=gi:4507388 /UG=Hs.155202 transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) /FL=gb:BC002883.1 gb:NM_003198.1 gb:L47345.1 NM_003198 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) TCEB3 6924 NM_003198 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202820_at NM_001621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001621.2 /DEF=Homo sapiens aryl hydrocarbon receptor (AHR), mRNA. /FEA=mRNA /GEN=AHR /PROD=aryl hydrocarbon receptor /DB_XREF=gi:5016091 /UG=Hs.170087 aryl hydrocarbon receptor /FL=gb:L19872.1 gb:D16354.1 gb:NM_001621.2 NM_001621 aryl hydrocarbon receptor AHR 196 NM_001621 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0007049 // cell cycle // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030888 // regulation of B cell proliferation // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0034752 // cytosolic aryl hydrocarbon receptor complex // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement /// 0046983 // protein dimerization activity // traceable author statement /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 202821_s_at AL044018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044018 /FEA=EST /DB_XREF=gi:5935931 /DB_XREF=est:DKFZp434J1028_s1 /CLONE=DKFZp434J1028 /UG=Hs.180398 LIM domain-containing preferred translocation partner in lipoma /FL=gb:NM_005578.1 AL044018 LIM domain containing preferred translocation partner in lipoma LPP 4026 NM_001167671 /// NM_001167672 /// NM_005578 /// XM_005247444 /// XM_005247445 /// XM_005247446 /// XM_005247447 /// XM_005247448 /// XM_005247450 /// XM_005247451 /// XM_005247453 /// XM_006713637 0007155 // cell adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202822_at BF221852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF221852 /FEA=EST /DB_XREF=gi:11129029 /DB_XREF=est:7p37f11.x1 /CLONE=IMAGE:3648141 /UG=Hs.180398 LIM domain-containing preferred translocation partner in lipoma /FL=gb:NM_005578.1 BF221852 LIM domain containing preferred translocation partner in lipoma LPP 4026 NM_001167671 /// NM_001167672 /// NM_005578 /// XM_005247444 /// XM_005247445 /// XM_005247446 /// XM_005247447 /// XM_005247448 /// XM_005247450 /// XM_005247451 /// XM_005247453 /// XM_006713637 0007155 // cell adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202823_at N89607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N89607 /FEA=EST /DB_XREF=gi:1442934 /DB_XREF=est:zb08h02.s1 /CLONE=IMAGE:301491 /UG=Hs.184693 transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) /FL=gb:NM_005648.1 gb:L34587.1 N89607 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) TCEB1 6921 NM_001204857 /// NM_001204858 /// NM_001204859 /// NM_001204860 /// NM_001204861 /// NM_001204862 /// NM_001204863 /// NM_001204864 /// NM_005648 /// XM_005251290 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0070449 // elongin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202824_s_at NM_005648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005648.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) (TCEB1), mRNA. /FEA=mRNA /GEN=TCEB1 /PROD=elongin C /DB_XREF=gi:5032160 /UG=Hs.184693 transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) /FL=gb:NM_005648.1 gb:L34587.1 NM_005648 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) TCEB1 6921 NM_001204857 /// NM_001204858 /// NM_001204859 /// NM_001204860 /// NM_001204861 /// NM_001204862 /// NM_001204863 /// NM_001204864 /// NM_005648 /// XM_005251290 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0070449 // elongin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202825_at NM_001151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001151.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (SLC25A4), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A4 /PROD=solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 4 /DB_XREF=gi:4502096 /UG=Hs.2043 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 /FL=gb:J02966.1 gb:NM_001151.1 NM_001151 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 SLC25A4 291 NM_001151 0000002 // mitochondrial genome maintenance // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015207 // adenine transmembrane transporter activity // traceable author statement 202826_at NM_003710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003710.1 /DEF=Homo sapiens serine protease inhibitor, Kunitz type 1 (SPINT1), mRNA. /FEA=mRNA /GEN=SPINT1 /PROD=hepatocyte growth factor activator inhibitorprecursor /DB_XREF=gi:4504328 /UG=Hs.233950 serine protease inhibitor, Kunitz type 1 /FL=gb:BC004140.1 gb:AB000095.1 gb:NM_003710.1 NM_003710 serine peptidase inhibitor, Kunitz type 1 SPINT1 6692 NM_001032367 /// NM_003710 /// NM_181642 /// XM_006720657 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202827_s_at AU149305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149305 /FEA=EST /DB_XREF=gi:11010826 /DB_XREF=est:AU149305 /CLONE=NT2RM4002036 /UG=Hs.2399 matrix metalloproteinase 14 (membrane-inserted) /FL=gb:U41078.1 gb:NM_004995.2 AU149305 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202828_s_at NM_004995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004995.2 /DEF=Homo sapiens matrix metalloproteinase 14 (membrane-inserted) (MMP14), mRNA. /FEA=mRNA /GEN=MMP14 /PROD=matrix metalloproteinase 14 preproprotein /DB_XREF=gi:13027797 /UG=Hs.2399 matrix metalloproteinase 14 (membrane-inserted) /FL=gb:U41078.1 gb:NM_004995.2 NM_004995 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202829_s_at NM_005638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005638.1 /DEF=Homo sapiens synaptobrevin-like 1 (SYBL1), mRNA. /FEA=mRNA /GEN=SYBL1 /PROD=synaptobrevin-like 1 /DB_XREF=gi:5032136 /UG=Hs.24167 synaptobrevin-like 1 /FL=gb:NM_005638.1 NM_005638 vesicle-associated membrane protein 7 VAMP7 6845 NM_001145149 /// NM_001185183 /// NM_005638 /// NR_033714 /// NR_033715 /// XM_006724835 /// XM_006724881 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // inferred from direct assay /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0034197 // triglyceride transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0043308 // eosinophil degranulation // inferred from sequence or structural similarity /// 0043312 // neutrophil degranulation // inferred from sequence or structural similarity /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1900483 // regulation of protein targeting to vacuolar membrane // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 202830_s_at NM_001467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001467.1 /DEF=Homo sapiens glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1 (G6PT1), mRNA. /FEA=mRNA /GEN=G6PT1 /PROD=glucose-6-phosphatase, transport(glucose-6-phosphate) protein 1 /DB_XREF=gi:4503846 /UG=Hs.26655 glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1 /FL=gb:BC002400.1 gb:BC003589.1 gb:NM_001467.1 gb:AF110819.1 NM_001467 solute carrier family 37 (glucose-6-phosphate transporter), member 4 SLC37A4 2542 NM_001164277 /// NM_001164278 /// NM_001164279 /// NM_001164280 /// NM_001467 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from direct assay /// 0015760 // glucose-6-phosphate transport // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032682 // negative regulation of chemokine production // inferred from electronic annotation /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045730 // respiratory burst // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from direct assay /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from mutant phenotype 202831_at NM_002083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002083.1 /DEF=Homo sapiens glutathione peroxidase 2 (gastrointestinal) (GPX2), mRNA. /FEA=mRNA /GEN=GPX2 /PROD=gastrointestinal glutathione peroxidase 2 /DB_XREF=gi:4504102 /UG=Hs.2704 glutathione peroxidase 2 (gastrointestinal) /FL=gb:NM_002083.1 NM_002083 glutathione peroxidase 2 (gastrointestinal) GPX2 2877 NM_002083 /// NR_046320 /// NR_046321 0001659 // temperature homeostasis // inferred from electronic annotation /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009609 // response to symbiotic bacterium // inferred from electronic annotation /// 0051702 // interaction with symbiont // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 202832_at NM_014635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014635.1 /DEF=Homo sapiens KIAA0336 gene product (KIAA0336), mRNA. /FEA=mRNA /GEN=KIAA0336 /PROD=KIAA0336 gene product /DB_XREF=gi:7662061 /UG=Hs.278671 KIAA0336 gene product /FL=gb:AF273042.1 gb:AB002334.1 gb:NM_014635.1 NM_014635 GRIP and coiled-coil domain containing 2 GCC2 9648 NM_181453 /// NR_028063 /// XM_006712870 /// XM_006712871 /// XM_006712872 /// XR_427125 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0034499 // late endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0070861 // regulation of protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0071955 // recycling endosome to Golgi transport // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202833_s_at NM_000295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000295.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), mRNA. /FEA=mRNA /GEN=SERPINA1 /PROD=serine (or cysteine) proteinase inhibitor, cladeA (alpha-1 antiproteinase, antitrypsin), member 1 /DB_XREF=gi:4505792 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 /FL=gb:AF130068.1 gb:M11465.1 gb:K01396.1 gb:NM_000295.1 NM_000295 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 SERPINA1 5265 NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202834_at NM_000029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000029.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 (SERPINA8), mRNA. /FEA=mRNA /GEN=SERPINA8 /PROD=angiotensinogen precursor /DB_XREF=gi:4557286 /UG=Hs.3697 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 /FL=gb:K02215.1 gb:NM_000029.1 NM_000029 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) AGT 183 NM_000029 0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // traceable author statement /// 0001822 // kidney development // inferred from mutant phenotype /// 0001974 // blood vessel remodeling // traceable author statement /// 0001991 // regulation of systemic arterial blood pressure by circulatory renin-angiotensin // inferred from electronic annotation /// 0001998 // angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001999 // renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002003 // angiotensin maturation // traceable author statement /// 0002016 // regulation of blood volume by renin-angiotensin // non-traceable author statement /// 0002018 // renin-angiotensin regulation of aldosterone production // non-traceable author statement /// 0002019 // regulation of renal output by angiotensin // non-traceable author statement /// 0002034 // regulation of blood vessel size by renin-angiotensin // traceable author statement /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0003014 // renal system process // inferred from direct assay /// 0003051 // angiotensin-mediated drinking behavior // inferred from electronic annotation /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0003331 // positive regulation of extracellular matrix constituent secretion // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from electronic annotation /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from mutant phenotype /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from electronic annotation /// 0014873 // response to muscle activity involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0030162 // regulation of proteolysis // not recorded /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // traceable author statement /// 0034104 // negative regulation of tissue remodeling // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // non-traceable author statement /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0035813 // regulation of renal sodium excretion // non-traceable author statement /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048659 // smooth muscle cell proliferation // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070471 // uterine smooth muscle contraction // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred by curator /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005179 // hormone activity // inferred by curator /// 0005179 // hormone activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0010698 // acetyltransferase activator activity // inferred from direct assay /// 0031701 // angiotensin receptor binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from physical interaction /// 0031703 // type 2 angiotensin receptor binding // inferred from physical interaction 202835_at BC001046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001046.1 /DEF=Homo sapiens, similar to S. pombe dim1+, clone MGC:1296, mRNA, complete cds. /FEA=mRNA /PROD=similar to S. pombe dim1+ /DB_XREF=gi:12654440 /UG=Hs.5074 similar to S. pombe dim1+ /FL=gb:BC001046.1 gb:AF023611.1 gb:NM_006701.1 gb:AF146373.1 BC001046 thioredoxin-like 4A TXNL4A 10907 NM_006701 /// XM_005266645 0000245 // spliceosomal complex assembly // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202836_s_at NM_006701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006701.1 /DEF=Homo sapiens similar to S. pombe dim1+ (DIM1), mRNA. /FEA=mRNA /GEN=DIM1 /PROD=similar to S. pombe dim1+ /DB_XREF=gi:5729801 /UG=Hs.5074 similar to S. pombe dim1+ /FL=gb:BC001046.1 gb:AF023611.1 gb:NM_006701.1 gb:AF146373.1 NM_006701 thioredoxin-like 4A TXNL4A 10907 NM_006701 /// XM_005266645 0000245 // spliceosomal complex assembly // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202837_at NM_006700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006700.1 /DEF=Homo sapiens FLN29 gene product (FLN29), mRNA. /FEA=mRNA /GEN=FLN29 /PROD=FLN29 gene product /DB_XREF=gi:5729827 /UG=Hs.5148 FLN29 gene product /FL=gb:BC003553.1 gb:AB007447.1 gb:NM_006700.1 NM_006700 TRAF-type zinc finger domain containing 1 TRAFD1 10906 NM_001143906 /// NM_006700 0034097 // response to cytokine // inferred from electronic annotation /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202838_at NM_000147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000147.1 /DEF=Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), mRNA. /FEA=mRNA /GEN=FUCA1 /PROD=fucosidase, alpha-L- 1, tissue /DB_XREF=gi:4503802 /UG=Hs.576 fucosidase, alpha-L- 1, tissue /FL=gb:M29877.1 gb:NM_000147.1 NM_000147 fucosidase, alpha-L- 1, tissue FUCA1 2517 NM_000147 /// XM_005245821 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from direct assay /// 0006027 // glycosaminoglycan catabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016139 // glycoside catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred by curator /// 0005764 // lysosome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004560 // alpha-L-fucosidase activity // inferred from direct assay /// 0004560 // alpha-L-fucosidase activity // traceable author statement /// 0015928 // fucosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042806 // fucose binding // not recorded 202839_s_at NM_004146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004146.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 (18kD, B18) (NDUFB7), mRNA. /FEA=mRNA /GEN=NDUFB7 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 7 (18kD, B18) /DB_XREF=gi:10764846 /UG=Hs.661 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 (18kD, B18) /FL=gb:NM_004146.2 gb:BC002595.1 gb:AF112200.1 gb:AF217091.1 NM_004146 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa NDUFB7 4713 NM_004146 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202840_at NM_003487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003487.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) (TAF2N), mRNA. /FEA=mRNA /GEN=TAF2N /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, N, 68kD (RNA-binding protein56) /DB_XREF=gi:4507352 /UG=Hs.66772 TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) /FL=gb:U51334.1 gb:NM_003487.1 NM_003487 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa TAF15 8148 NM_003487 /// NM_139215 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202841_x_at NM_007346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007346.1 /DEF=Homo sapiens 7-60 protein (7-60), mRNA. /FEA=mRNA /GEN=7-60 /PROD=7-60 protein /DB_XREF=gi:6671492 /UG=Hs.67896 7-60 protein /FL=gb:AF109134.1 gb:NM_007346.1 gb:AF172451.1 NM_007346 opioid growth factor receptor OGFR 11054 NM_007346 0001558 // regulation of cell growth // non-traceable author statement /// 0038003 // opioid receptor signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // non-traceable author statement 202842_s_at AL080081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080081.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F1862 (from clone DKFZp564F1862); complete cds. /FEA=mRNA /GEN=DKFZp564F1862 /PROD=hypothetical protein /DB_XREF=gi:5262493 /UG=Hs.6790 DnaJ (Hsp40) homolog, subfamily B, member 9 /FL=gb:AF083247.1 gb:AL080081.1 gb:AB026908.1 gb:NM_012328.1 AL080081 DnaJ (Hsp40) homolog, subfamily B, member 9 DNAJB9 4189 NM_012328 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 202843_at NM_012328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012328.1 /DEF=Homo sapiens microvascular endothelial differentiation gene 1 (MDG1), mRNA. /FEA=mRNA /GEN=MDG1 /PROD=microvascular endothelial differentiation gene1 /DB_XREF=gi:9558754 /UG=Hs.6790 DnaJ (Hsp40) homolog, subfamily B, member 9 /FL=gb:AF083247.1 gb:AL080081.1 gb:AB026908.1 gb:NM_012328.1 NM_012328 DnaJ (Hsp40) homolog, subfamily B, member 9 DNAJB9 4189 NM_012328 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 202844_s_at AW025261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW025261 /FEA=EST /DB_XREF=gi:5878791 /DB_XREF=est:wu95f02.x1 /CLONE=IMAGE:2527803 /UG=Hs.75447 ralA binding protein 1 /FL=gb:NM_006788.1 gb:L42542.1 AW025261 ralA binding protein 1 RALBP1 10928 NM_006788 /// XM_006722295 /// XM_006722296 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from physical interaction /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0043492 // ATPase activity, coupled to movement of substances // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction 202845_s_at NM_006788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006788.1 /DEF=Homo sapiens ralA binding protein 1 (RALBP1), mRNA. /FEA=mRNA /GEN=RALBP1 /PROD=ralA binding protein 1 /DB_XREF=gi:5803144 /UG=Hs.75447 ralA binding protein 1 /FL=gb:NM_006788.1 gb:L42542.1 NM_006788 ralA binding protein 1 RALBP1 10928 NM_006788 /// XM_006722295 /// XM_006722296 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from physical interaction /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0043492 // ATPase activity, coupled to movement of substances // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction 202846_s_at NM_002642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002642.1 /DEF=Homo sapiens phosphatidylinositol glycan, class C (PIGC), mRNA. /FEA=mRNA /GEN=PIGC /PROD=phosphatidylinositol glycan, class C /DB_XREF=gi:4505794 /UG=Hs.75790 phosphatidylinositol glycan, class C /FL=gb:D85418.1 gb:NM_002642.1 NM_002642 phosphatidylinositol glycan anchor biosynthesis, class C PIGC 5279 NM_002642 /// NM_153747 /// XM_006711383 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation 202847_at NM_004563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004563.1 /DEF=Homo sapiens phosphoenolpyruvate carboxykinase 2 (mitochondrial) (PCK2), mRNA. /FEA=mRNA /GEN=PCK2 /PROD=phosphoenolpyruvate carboxykinase 2(mitochondrial) /DB_XREF=gi:4758885 /UG=Hs.75812 phosphoenolpyruvate carboxykinase 2 (mitochondrial) /FL=gb:BC001454.1 gb:NM_004563.1 NM_004563 phosphoenolpyruvate carboxykinase 2 (mitochondrial) PCK2 5106 NM_001018073 /// NM_001291556 /// NM_004563 /// XM_005267726 /// XM_006720157 /// XM_006720158 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006116 // NADH oxidation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004611 // phosphoenolpyruvate carboxykinase activity // traceable author statement /// 0004613 // phosphoenolpyruvate carboxykinase (GTP) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202848_s_at BG423052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG423052 /FEA=EST /DB_XREF=gi:13329558 /DB_XREF=est:602450255F1 /CLONE=IMAGE:4588980 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:L16862.1 gb:NM_002082.1 BG423052 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202849_x_at NM_002082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002082.1 /DEF=Homo sapiens G protein-coupled receptor kinase 6 (GPRK6), mRNA. /FEA=mRNA /GEN=GPRK6 /PROD=G protein-coupled receptor kinase 6 /DB_XREF=gi:4504100 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:L16862.1 gb:NM_002082.1 NM_002082 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202850_at NM_002858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002858.2 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 3 (ABCD3), mRNA. /FEA=mRNA /GEN=ABCD3 /PROD=ATP-binding cassette, sub-family D, member 3 /DB_XREF=gi:10947125 /UG=Hs.76781 ATP-binding cassette, sub-family D (ALD), member 3 /FL=gb:NM_002858.2 gb:M81182.1 NM_002858 ATP-binding cassette, sub-family D (ALD), member 3 ABCD3 5825 NM_001122674 /// NM_002858 /// XM_005271088 /// XM_005271089 /// XM_006710802 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from direct assay /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0042760 // very long-chain fatty acid catabolic process // inferred from genetic interaction /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 202851_at AL136715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136715.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566A0646 (from clone DKFZp566A0646); complete cds. /FEA=mRNA /GEN=DKFZp566A0646 /PROD=hypothetical protein /DB_XREF=gi:12052948 /UG=Hs.77703 hypothetical protein FLJ11506 /FL=gb:AL136715.1 gb:NM_024666.1 AL136715 alpha- and gamma-adaptin binding protein AAGAB 79719 NM_001271885 /// NM_001271886 /// NM_024666 /// XM_005254664 /// XM_006720683 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 202852_s_at NM_024666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024666.1 /DEF=Homo sapiens hypothetical protein FLJ11506 (FLJ11506), mRNA. /FEA=mRNA /GEN=FLJ11506 /PROD=hypothetical protein FLJ11506 /DB_XREF=gi:13375923 /UG=Hs.77703 hypothetical protein FLJ11506 /FL=gb:AL136715.1 gb:NM_024666.1 NM_024666 alpha- and gamma-adaptin binding protein AAGAB 79719 NM_001271885 /// NM_001271886 /// NM_024666 /// XM_005254664 /// XM_006720683 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 202853_s_at NM_002958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002958.1 /DEF=Homo sapiens RYK receptor-like tyrosine kinase (RYK), mRNA. /FEA=mRNA /GEN=RYK /PROD=RYK receptor-like tyrosine kinase precursor /DB_XREF=gi:11863158 /UG=Hs.79350 RYK receptor-like tyrosine kinase /FL=gb:NM_002958.1 NM_002958 receptor-like tyrosine kinase RYK 6259 NM_001005861 /// NM_002958 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from electronic annotation /// 0042813 // Wnt-activated receptor activity // inferred from electronic annotation 202854_at NM_000194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000194.1 /DEF=Homo sapiens hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) (HPRT1), mRNA. /FEA=mRNA /GEN=HPRT1 /PROD=hypoxanthine phosphoribosyltransferase 1 /DB_XREF=gi:4504482 /UG=Hs.82314 hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) /FL=gb:BC000578.1 gb:M31642.1 gb:NM_000194.1 NM_000194 hypoxanthine phosphoribosyltransferase 1 HPRT1 3251 NM_000194 0001975 // response to amphetamine // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from mutant phenotype /// 0006166 // purine ribonucleoside salvage // inferred from mutant phenotype /// 0006168 // adenine salvage // not recorded /// 0006178 // guanine salvage // inferred from direct assay /// 0007610 // behavior // inferred from mutant phenotype /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0032263 // GMP salvage // not recorded /// 0032264 // IMP salvage // not recorded /// 0032264 // IMP salvage // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0043103 // hypoxanthine salvage // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045964 // positive regulation of dopamine metabolic process // inferred from mutant phenotype /// 0046038 // GMP catabolic process // inferred from direct assay /// 0046040 // IMP metabolic process // inferred from direct assay /// 0046083 // adenine metabolic process // inferred from electronic annotation /// 0046100 // hypoxanthine metabolic process // inferred from mutant phenotype /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004422 // hypoxanthine phosphoribosyltransferase activity // not recorded /// 0004422 // hypoxanthine phosphoribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052657 // guanine phosphoribosyltransferase activity // inferred from direct assay 202855_s_at AL513917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL513917 /FEA=EST /DB_XREF=gi:12777411 /DB_XREF=est:AL513917 /CLONE=CL0BA006ZD09 (3 prime) /UG=Hs.85838 solute carrier family 16 (monocarboxylic acid transporters), member 3 /FL=gb:U81800.1 gb:NM_004207.1 AL513917 microRNA 6787 /// solute carrier family 16 (monocarboxylate transporter), member 3 MIR6787 /// SLC16A3 9123 /// 102465472 NM_001042422 /// NM_001042423 /// NM_001206950 /// NM_001206951 /// NM_001206952 /// NM_004207 /// NR_106845 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202856_s_at NM_004207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004207.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 3 (SLC16A3), mRNA. /FEA=mRNA /GEN=SLC16A3 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 3 /DB_XREF=gi:4759111 /UG=Hs.85838 solute carrier family 16 (monocarboxylic acid transporters), member 3 /FL=gb:U81800.1 gb:NM_004207.1 NM_004207 microRNA 6787 /// solute carrier family 16 (monocarboxylate transporter), member 3 MIR6787 /// SLC16A3 9123 /// 102465472 NM_001042422 /// NM_001042423 /// NM_001206950 /// NM_001206951 /// NM_001206952 /// NM_004207 /// NR_106845 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202857_at NM_014255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014255.1 /DEF=Homo sapiens transmembrane protein 4 (TMEM4), mRNA. /FEA=mRNA /GEN=TMEM4 /PROD=transmembrane protein 4 /DB_XREF=gi:7657175 /UG=Hs.8752 transmembrane protein 4 /FL=gb:AB015631.1 gb:NM_014255.1 NM_014255 canopy FGF signaling regulator 2 CNPY2 10330 NM_001190991 /// NM_014255 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 202858_at NM_006758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006758.1 /DEF=Homo sapiens U2(RNU2) small nuclear RNA auxillary factor 1 (non-standard symbol) (U2AF1), mRNA. /FEA=mRNA /GEN=U2AF1 /PROD=U2 small nuclear RNA auxillary factor 1 /DB_XREF=gi:5803206 /UG=Hs.59271 U2(RNU2) small nuclear RNA auxillary factor 1 (non-standard symbol) /FL=gb:BC001177.1 gb:BC001923.1 gb:M96982.1 gb:NM_006758.1 NM_006758 U2 small nuclear RNA auxiliary factor 1 U2AF1 7307 NM_001025203 /// NM_001025204 /// NM_006758 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050733 // RS domain binding // inferred from electronic annotation 202859_x_at NM_000584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000584.1 /DEF=Homo sapiens interleukin 8 (IL8), mRNA. /FEA=mRNA /GEN=IL8 /PROD=interleukin 8 /DB_XREF=gi:10834977 /UG=Hs.624 interleukin 8 /FL=gb:NM_000584.1 gb:M17017.1 gb:M26383.1 NM_000584 chemokine (C-X-C motif) ligand 8 CXCL8 3576 NM_000584 0001525 // angiogenesis // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from genetic interaction /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031623 // receptor internalization // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042119 // neutrophil activation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045091 // regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0050930 // induction of positive chemotaxis // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0090023 // positive regulation of neutrophil chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005153 // interleukin-8 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // traceable author statement 202860_at NM_014856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014856.1 /DEF=Homo sapiens KIAA0476 gene product (KIAA0476), mRNA. /FEA=mRNA /GEN=KIAA0476 /PROD=KIAA0476 gene product /DB_XREF=gi:7662151 /UG=Hs.6684 KIAA0476 gene product /FL=gb:AB007945.1 gb:NM_014856.1 NM_014856 DENN/MADD domain containing 4B DENND4B 9909 NM_014856 /// XM_005245678 /// XM_005245679 /// XM_006711690 /// XM_006711691 /// XR_426806 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032483 // regulation of Rab protein signal transduction // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 202861_at NM_002616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002616.1 /DEF=Homo sapiens period (Drosophila) homolog 1 (PER1), mRNA. /FEA=mRNA /GEN=PER1 /PROD=period 1 /DB_XREF=gi:4505712 /UG=Hs.68398 period (Drosophila) homolog 1 /FL=gb:AF022991.1 gb:AB002107.1 gb:NM_002616.1 NM_002616 microRNA 6883 /// period circadian clock 1 MIR6883 /// PER1 5187 /// 102465532 NM_002616 /// NR_106943 /// XM_005256689 /// XM_005256690 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from expression pattern /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // traceable author statement /// 0010608 // posttranscriptional regulation of gene expression // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity /// 1900015 // regulation of cytokine production involved in inflammatory response // inferred from sequence or structural similarity /// 1900744 // regulation of p38MAPK cascade // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from sequence or structural similarity /// 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay 202862_at NM_000137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000137.1 /DEF=Homo sapiens fumarylacetoacetate (FAH), mRNA. /FEA=mRNA /GEN=FAH /PROD=fumarylacetoacetase /DB_XREF=gi:4557586 /UG=Hs.73875 fumarylacetoacetate /FL=gb:BC002527.1 gb:M55150.1 gb:NM_000137.1 NM_000137 fumarylacetoacetate hydrolase (fumarylacetoacetase) FAH 2184 NM_000137 0006527 // arginine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004334 // fumarylacetoacetase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202863_at NM_003113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003113.1 /DEF=Homo sapiens nuclear antigen Sp100 (SP100), mRNA. /FEA=mRNA /GEN=SP100 /PROD=nuclear antigen Sp100 /DB_XREF=gi:4507164 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:M60618.1 gb:NM_003113.1 NM_003113 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 202864_s_at NM_003113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003113.1 /DEF=Homo sapiens nuclear antigen Sp100 (SP100), mRNA. /FEA=mRNA /GEN=SP100 /PROD=nuclear antigen Sp100 /DB_XREF=gi:4507164 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:M60618.1 gb:NM_003113.1 NM_003113 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 202865_at AI695173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI695173 /FEA=EST /DB_XREF=gi:4983073 /DB_XREF=est:we47h05.x1 /CLONE=IMAGE:2344281 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1 AI695173 DnaJ (Hsp40) homolog, subfamily B, member 12 DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202866_at BG283782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG283782 /FEA=EST /DB_XREF=gi:13034069 /DB_XREF=est:602408085F1 /CLONE=IMAGE:4520181 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1 BG283782 DnaJ (Hsp40) homolog, subfamily B, member 12 DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202867_s_at NM_017626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017626.1 /DEF=Homo sapiens hypothetical protein FLJ20027 (FLJ20027), mRNA. /FEA=mRNA /GEN=FLJ20027 /PROD=hypothetical protein FLJ20027 /DB_XREF=gi:8923029 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1 NM_017626 DnaJ (Hsp40) homolog, subfamily B, member 12 DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202868_s_at NM_006627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006627.1 /DEF=Homo sapiens POP4 (processing of precursor , S. cerevisiae) homolog (POP4), mRNA. /FEA=mRNA /GEN=POP4 /PROD=POP4 (processing of precursor , S. cerevisiae)homolog /DB_XREF=gi:5729985 /UG=Hs.82238 POP4 (processing of precursor , S. cerevisiae) homolog /FL=gb:BC004438.1 gb:AF001176.2 gb:NM_006627.1 NM_006627 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) POP4 10775 NM_006627 /// NR_027368 0006364 // rRNA processing // inferred from electronic annotation /// 0006379 // mRNA cleavage // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0000172 // ribonuclease MRP complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005655 // nucleolar ribonuclease P complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030677 // ribonuclease P complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 202869_at NM_016816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016816.1 /DEF=Homo sapiens 2,5-oligoadenylate synthetase 1 (40-46 kD) (OAS1), transcript variant E18, mRNA. /FEA=mRNA /GEN=OAS1 /PROD=2,5-oligoadenylate synthetase 1, isoform E18 /DB_XREF=gi:8051620 /UG=Hs.82396 2,5-oligoadenylate synthetase 1 (40-46 kD) /FL=gb:NM_016816.1 NM_016816 2'-5'-oligoadenylate synthetase 1, 40/46kDa OAS1 4938 NM_001032409 /// NM_002534 /// NM_016816 /// XM_006719434 0002376 // immune system process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006164 // purine nucleotide biosynthetic process // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060700 // regulation of ribonuclease activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202870_s_at NM_001255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001255.1 /DEF=Homo sapiens CDC20 (cell division cycle 20, S. cerevisiae, homolog) (CDC20), mRNA. /FEA=mRNA /GEN=CDC20 /PROD=cell division cycle 20 /DB_XREF=gi:4557436 /UG=Hs.82906 CDC20 (cell division cycle 20, S. cerevisiae, homolog) /FL=gb:BC001088.1 gb:AF099644.1 gb:NM_001255.1 gb:U05340.1 NM_001255 cell division cycle 20 CDC20 991 NM_001255 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031915 // positive regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 202871_at NM_004295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004295.1 /DEF=Homo sapiens TNF receptor-associated factor 4 (TRAF4), mRNA. /FEA=mRNA /GEN=TRAF4 /PROD=TNF receptor-associated factor 4 /DB_XREF=gi:4759251 /UG=Hs.8375 TNF receptor-associated factor 4 /FL=gb:BC001769.1 gb:NM_004295.1 NM_004295 TNF receptor-associated factor 4 TRAF4 9618 NM_004295 /// NM_145751 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 202872_at AW024925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024925 /FEA=EST /DB_XREF=gi:5878455 /DB_XREF=est:wu92g09.x1 /CLONE=IMAGE:2527552 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1 AW024925 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 202873_at BF034973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF034973 /FEA=EST /DB_XREF=gi:10742685 /DB_XREF=est:601459039F1 /CLONE=IMAGE:3862832 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1 BF034973 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 202874_s_at NM_001695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001695.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD (ATP6C), mRNA. /FEA=mRNA /GEN=ATP6C /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 42kD /DB_XREF=gi:4502314 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1 NM_001695 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 202875_s_at BE397715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE397715 /FEA=EST /DB_XREF=gi:9343080 /DB_XREF=est:601289842F1 /CLONE=IMAGE:3620290 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:NM_002586.1 BE397715 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202876_s_at NM_002586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002586.1 /DEF=Homo sapiens pre-B-cell leukemia transcription factor 2 (PBX2), mRNA. /FEA=mRNA /GEN=PBX2 /PROD=pre-B-cell leukemia transcription factor 2 /DB_XREF=gi:4505624 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:NM_002586.1 NM_002586 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202877_s_at W72082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W72082 /FEA=EST /DB_XREF=gi:1382588 /DB_XREF=est:zd70c06.s1 /CLONE=IMAGE:345994 /UG=Hs.97199 complement component C1q receptor /FL=gb:NM_012072.2 gb:U94333.1 W72082 CD93 molecule CD93 22918 NM_012072 0006909 // phagocytosis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042116 // macrophage activation // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0001849 // complement component C1q binding // inferred from direct assay /// 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 202878_s_at NM_012072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012072.2 /DEF=Homo sapiens complement component C1q receptor (C1QR), mRNA. /FEA=mRNA /GEN=C1QR /PROD=complement component C1q receptor /DB_XREF=gi:11496985 /UG=Hs.97199 complement component C1q receptor /FL=gb:NM_012072.2 gb:U94333.1 NM_012072 CD93 molecule CD93 22918 NM_012072 0006909 // phagocytosis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042116 // macrophage activation // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0001849 // complement component C1q binding // inferred from direct assay /// 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 202879_s_at AI798823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI798823 /FEA=EST /DB_XREF=gi:5364295 /DB_XREF=est:we93b05.x1 /CLONE=IMAGE:2348625 /UG=Hs.1050 pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) /FL=gb:M85169.1 gb:NM_004762.1 gb:NM_017456.1 AI798823 cytohesin 1 CYTH1 9267 NM_001292018 /// NM_001292019 /// NM_004762 /// NM_017456 /// XM_006722180 /// XM_006722181 /// XM_006722182 /// XM_006722183 /// XM_006722184 /// XM_006722185 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 202880_s_at NM_004762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004762.1 /DEF=Homo sapiens pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) (PSCD1), transcript variant 1, mRNA. /FEA=mRNA /GEN=PSCD1 /PROD=cytohesin 1, isoform 1 /DB_XREF=gi:4758963 /UG=Hs.1050 pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) /FL=gb:M85169.1 gb:NM_004762.1 gb:NM_017456.1 NM_004762 cytohesin 1 CYTH1 9267 NM_001292018 /// NM_001292019 /// NM_004762 /// NM_017456 /// XM_006722180 /// XM_006722181 /// XM_006722182 /// XM_006722183 /// XM_006722184 /// XM_006722185 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 202881_x_at AF172066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF172066.2 /DEF=Homo sapiens retinoic acid repressible protein (RARG-1) mRNA, complete cds. /FEA=mRNA /GEN=RARG-1 /PROD=retinoic acid repressible protein /DB_XREF=gi:13559882 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF172066.2 gb:NM_016167.2 AF172066 202882_x_at NM_016167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016167.2 /DEF=Homo sapiens retinoic acid repressible protein (RARG-1), mRNA. /FEA=mRNA /GEN=RARG-1 /PROD=retinoic acid repressible protein /DB_XREF=gi:13569842 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF172066.2 gb:NM_016167.2 NM_016167 nucleolar protein 7, 27kDa NOL7 51406 NM_016167 /// XM_005249173 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202883_s_at T79584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T79584 /FEA=EST /DB_XREF=gi:698093 /DB_XREF=est:yd71a11.s1 /CLONE=IMAGE:113660 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1 T79584 protein phosphatase 2, regulatory subunit A, beta PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202884_s_at NM_002716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002716.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (PPP2R1B), mRNA. /FEA=mRNA /GEN=PPP2R1B /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit A (PR 65), beta isoform /DB_XREF=gi:11386166 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1 NM_002716 protein phosphatase 2, regulatory subunit A, beta PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202885_s_at AF163473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF163473.1 /DEF=Homo sapiens protein phosphatase 2A regulatory subunit A beta isoform (PPP2R1B) mRNA, complete cds. /FEA=mRNA /GEN=PPP2R1B /PROD=protein phosphatase 2A regulatory subunit A betaisoform /DB_XREF=gi:11692008 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1 AF163473 protein phosphatase 2, regulatory subunit A, beta PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202886_s_at M65254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M65254.1 /DEF=Protein phosphatase 2A 65 kDa regulatory subunit-beta mRNA, complete cds. /FEA=mRNA /GEN=SNRPEP1 /PROD=protein phosphatase-2A regulatory subunit-beta /DB_XREF=gi:189429 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1 M65254 protein phosphatase 2, regulatory subunit A, beta PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202887_s_at NM_019058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019058.1 /DEF=Homo sapiens hypothetical protein (FLJ20500), mRNA. /FEA=mRNA /GEN=FLJ20500 /PROD=hypothetical protein /DB_XREF=gi:9506686 /UG=Hs.111244 hypothetical protein /FL=gb:AL136668.1 gb:NM_019058.1 NM_019058 DNA-damage-inducible transcript 4 DDIT4 54541 NM_019058 0001666 // response to hypoxia // inferred from direct assay /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0043241 // protein complex disassembly // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 1901216 // positive regulation of neuron death // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0071889 // 14-3-3 protein binding // inferred from electronic annotation 202888_s_at NM_001150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001150.1 /DEF=Homo sapiens alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) (ANPEP), mRNA. /FEA=mRNA /GEN=ANPEP /PROD=membrane alanine aminopeptidase precursor /DB_XREF=gi:4502094 /UG=Hs.1239 alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) /FL=gb:M22324.1 gb:NM_001150.1 NM_001150 alanyl (membrane) aminopeptidase ANPEP 290 NM_001150 /// XM_005254892 0001525 // angiogenesis // inferred from electronic annotation /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202889_x_at T62571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T62571 /FEA=EST /DB_XREF=gi:666228 /DB_XREF=est:yc04h01.s1 /CLONE=IMAGE:79729 /UG=Hs.146388 microtubule-associated protein 7 /FL=gb:NM_003980.1 T62571 microtubule-associated protein 7 MAP7 9053 NM_001198608 /// NM_001198609 /// NM_001198611 /// NM_001198614 /// NM_001198615 /// NM_001198616 /// NM_001198617 /// NM_001198618 /// NM_001198619 /// NM_003980 /// XM_005267209 /// XM_006715598 /// XM_006715599 /// XM_006715600 /// XM_006715601 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from sequence or structural similarity /// 0006997 // nucleus organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202890_at AW242297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242297 /FEA=EST /DB_XREF=gi:6576051 /DB_XREF=est:xm96b11.x1 /CLONE=IMAGE:2692029 /UG=Hs.146388 microtubule-associated protein 7 /FL=gb:NM_003980.1 AW242297 microtubule-associated protein 7 MAP7 9053 NM_001198608 /// NM_001198609 /// NM_001198611 /// NM_001198614 /// NM_001198615 /// NM_001198616 /// NM_001198617 /// NM_001198618 /// NM_001198619 /// NM_003980 /// XM_005267209 /// XM_006715598 /// XM_006715599 /// XM_006715600 /// XM_006715601 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from sequence or structural similarity /// 0006997 // nucleus organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement 202891_at NM_005600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005600.1 /DEF=Homo sapiens nitrilase 1 (NIT1), mRNA. /FEA=mRNA /GEN=NIT1 /PROD=nitrilase 1 /DB_XREF=gi:5031946 /UG=Hs.146406 nitrilase 1 /FL=gb:AF069987.1 gb:NM_005600.1 NM_005600 nitrilase 1 NIT1 4817 NM_001185092 /// NM_001185093 /// NM_001185094 /// NM_005600 /// XM_005245214 /// XM_005245215 /// XM_005245216 /// XM_006711341 0006807 // nitrogen compound metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000257 // nitrilase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation 202892_at NM_004661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004661.1 /DEF=Homo sapiens CDC23 (cell division cycle 23, yeast, homolog) (CDC23), mRNA. /FEA=mRNA /GEN=CDC23 /PROD=cell division cycle 23, yeast homolog; CDC23 /DB_XREF=gi:4757947 /UG=Hs.153546 CDC23 (cell division cycle 23, yeast, homolog) /FL=gb:AF053977.1 gb:AB011472.1 gb:NM_004661.1 gb:AF191341.1 NM_004661 cell division cycle 23 CDC23 8697 NM_004661 0000080 // mitotic G1 phase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0007080 // mitotic metaphase plate congression // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007096 // regulation of exit from mitosis // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202893_at NM_006377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006377.1 /DEF=Homo sapiens UNC13 (C. elegans)-like (UNC13), mRNA. /FEA=mRNA /GEN=UNC13 /PROD=UNC13 (C. elegans)-like /DB_XREF=gi:5454147 /UG=Hs.155001 UNC13 (C. elegans)-like /FL=gb:AF020202.1 gb:NM_006377.1 NM_006377 unc-13 homolog B (C. elegans) UNC13B 10497 NM_006377 /// XM_006716716 0006887 // exocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202894_at NM_004444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004444.1 /DEF=Homo sapiens EphB4 (EPHB4) mRNA. /FEA=mRNA /GEN=HTK /PROD=EphB4 /DB_XREF=gi:4758289 /UG=Hs.155227 EphB4 /FL=gb:NM_004444.1 gb:U07695.1 NM_004444 EPH receptor B4 EPHB4 2050 NM_004444 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 202895_s_at D86043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86043.1 /DEF=Homo sapiens mRNA for SHPS-1, complete cds. /FEA=mRNA /PROD=SHPS-1 /DB_XREF=gi:1864010 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1 D86043 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202896_s_at NM_004648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004648.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type substrate 1 (PTPNS1), mRNA. /FEA=mRNA /GEN=PTPNS1 /PROD=protein tyrosine phosphatase, non-receptor typesubstrate 1 /DB_XREF=gi:4758977 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1 NM_004648 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202897_at AB023430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB023430.1 /DEF=Homo sapiens Bit mRNA, complete cds. /FEA=mRNA /GEN=Bit /DB_XREF=gi:6518912 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1 AB023430 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202898_at NM_014654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014654.1 /DEF=Homo sapiens KIAA0468 gene product (KIAA0468), mRNA. /FEA=mRNA /GEN=KIAA0468 /PROD=KIAA0468 gene product /DB_XREF=gi:7662137 /UG=Hs.158287 KIAA0468 gene product /FL=gb:AB007937.1 gb:NM_014654.1 NM_014654 syndecan 3 SDC3 9672 NM_014654 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0008092 // cytoskeletal protein binding // inferred from electronic annotation 202899_s_at NM_003017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003017.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 3 (SFRS3), mRNA. /FEA=mRNA /GEN=SFRS3 /PROD=splicing factor, arginineserine-rich 3 /DB_XREF=gi:4506900 /UG=Hs.167460 splicing factor, arginineserine-rich 3 /FL=gb:L10838.1 gb:NM_003017.1 NM_003017 serine/arginine-rich splicing factor 3 SRSF3 6428 NM_003017 /// NR_036610 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 2028_s_at M96577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank M96577 /FEATURE= /DEFINITION=HUME2F Homo sapiens (E2F-1) pRB-binding protein mRNA, complete cds M96577 E2F transcription factor 1 E2F1 1869 NM_005225 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000080 // mitotic G1 phase // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0043276 // anoikis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048255 // mRNA stabilization // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035189 // Rb-E2F complex // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202900_s_at NM_002532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002532.2 /DEF=Homo sapiens nucleoporin 88kD (NUP88), mRNA. /FEA=mRNA /GEN=NUP88 /PROD=nucleoporin 88kD /DB_XREF=gi:5729954 /UG=Hs.172108 nucleoporin 88kD /FL=gb:BC000335.1 gb:NM_002532.2 NM_002532 nucleoporin 88kDa NUP88 4927 NM_002532 /// XM_005256659 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005215 // transporter activity // traceable author statement 202901_x_at BC002642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002642.1 /DEF=Homo sapiens, cathepsin S, clone MGC:3886, mRNA, complete cds. /FEA=mRNA /PROD=cathepsin S /DB_XREF=gi:12803614 /UG=Hs.181301 cathepsin S /FL=gb:BC002642.1 gb:M86553.1 gb:NM_004079.1 gb:M90696.1 BC002642 cathepsin S CTSS 1520 NM_001199739 /// NM_004079 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202902_s_at NM_004079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004079.1 /DEF=Homo sapiens cathepsin S (CTSS), mRNA. /FEA=mRNA /GEN=CTSS /PROD=cathepsin S /DB_XREF=gi:4758097 /UG=Hs.181301 cathepsin S /FL=gb:BC002642.1 gb:M86553.1 gb:NM_004079.1 gb:M90696.1 NM_004079 cathepsin S CTSS 1520 NM_001199739 /// NM_004079 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202903_at AU153477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153477 /FEA=EST /DB_XREF=gi:11014998 /DB_XREF=est:AU153477 /CLONE=NT2RP3003272 /UG=Hs.227280 U6 snRNA-associated Sm-like protein /FL=gb:AF182291.1 gb:NM_012322.1 AU153477 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM5 23658 NM_001130710 /// NM_001139499 /// NM_012322 /// NR_024466 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202904_s_at NM_012322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012322.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein (LSM5), mRNA. /FEA=mRNA /GEN=LSM5 /PROD=U6 snRNA-associated Sm-like protein /DB_XREF=gi:6912487 /UG=Hs.227280 U6 snRNA-associated Sm-like protein /FL=gb:AF182291.1 gb:NM_012322.1 NM_012322 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM5 23658 NM_001130710 /// NM_001139499 /// NM_012322 /// NR_024466 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202905_x_at AI796269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796269 /FEA=EST /DB_XREF=gi:5361732 /DB_XREF=est:wh44g10.x1 /CLONE=IMAGE:2383650 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2 AI796269 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202906_s_at AF049895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF049895 /DEF=Homo sapiens 8q21.3: Nibrin (NBS1), 2,4-dienoyl-CoA reductase (DECR), and calbindin 1 (CALB1) genes /FEA=mRNA_5 /DB_XREF=gi:4126312 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2 AF049895 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202907_s_at NM_002485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002485.2 /DEF=Homo sapiens Nijmegen breakage syndrome 1 (nibrin) (NBS1), mRNA. /FEA=mRNA /GEN=NBS1 /PROD=nibrin /DB_XREF=gi:6996019 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2 NM_002485 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202908_at NM_006005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006005.2 /DEF=Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), mRNA. /FEA=mRNA /GEN=WFS1 /PROD=Wolfram syndrome protein /DB_XREF=gi:13376995 /UG=Hs.26077 Wolfram syndrome 1 (wolframin) /FL=gb:NM_006005.2 gb:AF084481.1 NM_006005 Wolfram syndrome 1 (wolframin) WFS1 7466 NM_001145853 /// NM_006005 0001822 // kidney development // inferred from mutant phenotype /// 0003091 // renal water homeostasis // inferred from mutant phenotype /// 0006983 // ER overload response // inferred by curator /// 0006983 // ER overload response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022417 // protein maturation by protein folding // inferred by curator /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042048 // olfactory behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0051247 // positive regulation of protein metabolic process // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0070845 // polyubiquitinated misfolded protein transport // inferred from sequence or structural similarity /// 1902236 // negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0033613 // activating transcription factor binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 202909_at NM_014805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014805.1 /DEF=Homo sapiens KIAA0766 gene product (KIAA0766), mRNA. /FEA=mRNA /GEN=KIAA0766 /PROD=KIAA0766 gene product /DB_XREF=gi:7662293 /UG=Hs.28020 KIAA0766 gene product /FL=gb:AF059751.1 gb:AB018309.1 gb:NM_014805.1 NM_014805 EPM2A (laforin) interacting protein 1 EPM2AIP1 9852 NM_014805 0005783 // endoplasmic reticulum // inferred from electronic annotation 202910_s_at NM_001784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001784.1 /DEF=Homo sapiens CD97 antigen (CD97), mRNA. /FEA=mRNA /GEN=CD97 /PROD=CD97 antigen /DB_XREF=gi:4502690 /UG=Hs.3107 CD97 antigen /FL=gb:NM_001784.1 NM_001784 CD97 molecule CD97 976 NM_001025160 /// NM_001784 /// NM_078481 /// XM_005260170 /// XM_005260171 /// XM_005260172 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202911_at NM_000179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000179.1 /DEF=Homo sapiens mutS (E. coli) homolog 6 (MSH6), mRNA. /FEA=mRNA /GEN=MSH6 /PROD=mutS (E. coli) homolog 6 /DB_XREF=gi:4504190 /UG=Hs.3248 mutS (E. coli) homolog 6 /FL=gb:U28946.1 gb:BC004246.1 gb:NM_000179.1 gb:U54777.2 NM_000179 mutS homolog 6 MSH6 2956 NM_000179 /// NM_001281492 /// NM_001281493 /// NM_001281494 /// XM_005264271 0000710 // meiotic mismatch repair // not recorded /// 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from sequence or structural similarity /// 0009411 // response to UV // not recorded /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000228 // nuclear chromosome // not recorded /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 202912_at NM_001124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001124.1 /DEF=Homo sapiens adrenomedullin (ADM), mRNA. /FEA=mRNA /GEN=ADM /PROD=adrenomedullin /DB_XREF=gi:4501944 /UG=Hs.394 adrenomedullin /FL=gb:NM_001124.1 gb:D14874.1 NM_001124 adrenomedullin ADM 133 NM_001124 0001570 // vasculogenesis // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006701 // progesterone biosynthetic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045906 // negative regulation of vasoconstriction // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046879 // hormone secretion // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from electronic annotation /// 2001214 // positive regulation of vasculogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031700 // adrenomedullin receptor binding // inferred from electronic annotation 202913_at AI090007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI090007 /FEA=EST /DB_XREF=gi:3429066 /DB_XREF=est:qb13h01.x1 /CLONE=IMAGE:1696177 /UG=Hs.47822 Rho guanine exchange factor (GEF) 11 /FL=gb:AB002378.1 gb:NM_014784.1 AI090007 Rho guanine nucleotide exchange factor (GEF) 11 ARHGEF11 9826 NM_014784 /// NM_198236 /// XM_005245629 /// XM_005245633 /// XM_006711659 /// XM_006711660 /// XM_006711661 /// XM_006711662 /// XM_006711663 /// XM_006711664 /// XM_006711665 0000910 // cytokinesis // non-traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006941 // striated muscle contraction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0030010 // establishment of cell polarity // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202914_s_at NM_014784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014784.1 /DEF=Homo sapiens Rho guanine exchange factor (GEF) 11 (ARHGEF11), mRNA. /FEA=mRNA /GEN=ARHGEF11 /PROD=Rho guanine exchange factor (GEF) 11 /DB_XREF=gi:7662085 /UG=Hs.47822 Rho guanine exchange factor (GEF) 11 /FL=gb:AB002378.1 gb:NM_014784.1 NM_014784 Rho guanine nucleotide exchange factor (GEF) 11 ARHGEF11 9826 NM_014784 /// NM_198236 /// XM_005245629 /// XM_005245633 /// XM_006711659 /// XM_006711660 /// XM_006711661 /// XM_006711662 /// XM_006711663 /// XM_006711664 /// XM_006711665 0000910 // cytokinesis // non-traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006941 // striated muscle contraction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0030010 // establishment of cell polarity // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 202915_s_at BF115776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF115776 /FEA=EST /DB_XREF=gi:10985252 /DB_XREF=est:7n64f10.x1 /CLONE=IMAGE:3569442 /UG=Hs.5737 KIAA0475 gene product /FL=gb:AB007944.1 gb:NM_014864.1 BF115776 family with sequence similarity 20, member B FAM20B 9917 NM_014864 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from direct assay 202916_s_at NM_014864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014864.1 /DEF=Homo sapiens KIAA0475 gene product (KIAA0475), mRNA. /FEA=mRNA /GEN=KIAA0475 /PROD=KIAA0475 gene product /DB_XREF=gi:7662149 /UG=Hs.5737 KIAA0475 gene product /FL=gb:AB007944.1 gb:NM_014864.1 NM_014864 family with sequence similarity 20, member B FAM20B 9917 NM_014864 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from direct assay 202917_s_at NM_002964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002964.2 /DEF=Homo sapiens S100 calcium-binding protein A8 (calgranulin A) (S100A8), mRNA. /FEA=mRNA /GEN=S100A8 /PROD=S100 calcium-binding protein A8 /DB_XREF=gi:9845519 /UG=Hs.100000 S100 calcium-binding protein A8 (calgranulin A) /FL=gb:NM_002964.2 NM_002964 S100 calcium binding protein A8 S100A8 6279 NM_002964 0001816 // cytokine production // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006914 // autophagy // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0032119 // sequestering of zinc ion // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032602 // chemokine production // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0070488 // neutrophil aggregation // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0035662 // Toll-like receptor 4 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // traceable author statement /// 0050786 // RAGE receptor binding // traceable author statement 202918_s_at AF151853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151853.1 /DEF=Homo sapiens CGI-95 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-95 protein /DB_XREF=gi:4929658 /UG=Hs.107942 DKFZP564M112 protein /FL=gb:AB015441.1 gb:BC005237.1 gb:AF151853.1 gb:AL080070.1 gb:NM_015387.1 AF151853 HSPE1-MOB4 readthrough /// MOB family member 4, phocein HSPE1-MOB4 /// MOB4 25843 /// 100529241 NM_001100819 /// NM_001202485 /// NM_001204094 /// NM_015387 /// NM_199482 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202919_at NM_015387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015387.1 /DEF=Homo sapiens DKFZP564M112 protein (DKFZP564M112), mRNA. /FEA=mRNA /GEN=DKFZP564M112 /PROD=DKFZP564M112 protein /DB_XREF=gi:7661623 /UG=Hs.107942 DKFZP564M112 protein /FL=gb:AB015441.1 gb:BC005237.1 gb:AF151853.1 gb:AL080070.1 gb:NM_015387.1 NM_015387 MOB family member 4, phocein MOB4 25843 NM_001100819 /// NM_001204094 /// NM_015387 /// NM_199482 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202920_at BF726212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF726212 /FEA=EST /DB_XREF=gi:12042123 /DB_XREF=est:by03a08.y1 /CLONE=by03a08 /UG=Hs.117970 ankyrin 2, neuronal /FL=gb:NM_001148.2 BF726212 ankyrin 2, neuronal ANK2 287 NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 202921_s_at NM_001148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001148.2 /DEF=Homo sapiens ankyrin 2, neuronal (ANK2), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANK2 /PROD=ankyrin 2, isoform 1 /DB_XREF=gi:10947051 /UG=Hs.117970 ankyrin 2, neuronal /FL=gb:NM_001148.2 NM_001148 ankyrin 2, neuronal ANK2 287 NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 202922_at BF676980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF676980 /FEA=EST /DB_XREF=gi:11950875 /DB_XREF=est:602084207F1 /CLONE=IMAGE:4248744 /UG=Hs.151393 glutamate-cysteine ligase, catalytic subunit /FL=gb:M90656.1 gb:NM_001498.1 BF676980 glutamate-cysteine ligase, catalytic subunit GCLC 2729 NM_001197115 /// NM_001498 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009408 // response to heat // inferred from direct assay /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from direct assay /// 0019852 // L-ascorbic acid metabolic process // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from physical interaction 202923_s_at NM_001498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001498.1 /DEF=Homo sapiens glutamate-cysteine ligase, catalytic subunit (GCLC), mRNA. /FEA=mRNA /GEN=GCLC /PROD=glutamate-cysteine ligase /DB_XREF=gi:4557624 /UG=Hs.151393 glutamate-cysteine ligase, catalytic subunit /FL=gb:M90656.1 gb:NM_001498.1 NM_001498 glutamate-cysteine ligase, catalytic subunit GCLC 2729 NM_001197115 /// NM_001498 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009408 // response to heat // inferred from direct assay /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from direct assay /// 0019852 // L-ascorbic acid metabolic process // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from physical interaction 202924_s_at AL562280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL562280 /FEA=EST /DB_XREF=gi:12910544 /DB_XREF=est:AL562280 /CLONE=CS0DC003YF04 (3 prime) /UG=Hs.154104 pleiomorphic adenoma gene-like 2 /FL=gb:AF006005.1 gb:NM_002657.2 AL562280 pleiomorphic adenoma gene-like 2 PLAGL2 5326 NM_002657 /// XM_005260436 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034378 // chylomicron assembly // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202925_s_at NM_002657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002657.2 /DEF=Homo sapiens pleiomorphic adenoma gene-like 2 (PLAGL2), mRNA. /FEA=mRNA /GEN=PLAGL2 /PROD=pleiomorphic adenoma gene-like 2 /DB_XREF=gi:6031195 /UG=Hs.154104 pleiomorphic adenoma gene-like 2 /FL=gb:AF006005.1 gb:NM_002657.2 NM_002657 pleiomorphic adenoma gene-like 2 PLAGL2 5326 NM_002657 /// XM_005260436 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034378 // chylomicron assembly // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202926_at NM_015909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015909.1 /DEF=Homo sapiens neuroblastoma-amplified protein (LOC51594), mRNA. /FEA=mRNA /GEN=LOC51594 /PROD=neuroblastoma-amplified protein /DB_XREF=gi:7706239 /UG=Hs.15430 neuroblastoma-amplified protein /FL=gb:AF056195.1 gb:NM_015909.1 NM_015909 neuroblastoma amplified sequence NBAS 51594 NM_015909 /// NR_052013 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 202927_at NM_006221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006221.1 /DEF=Homo sapiens protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1 (PIN1), mRNA. /FEA=mRNA /GEN=PIN1 /PROD=protein (peptidyl-prolyl cistrans isomerase)NIMA-interacting 1 /DB_XREF=gi:5453897 /UG=Hs.161362 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1 /FL=gb:BC002899.1 gb:U49070.1 gb:NM_006221.1 NM_006221 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 PIN1 5300 NM_006221 /// NR_038422 /// NR_038830 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from genetic interaction /// 0006457 // protein folding // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032465 // regulation of cytokinesis // inferred from genetic interaction /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 2000146 // negative regulation of cell motility // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from direct assay /// 0050816 // phosphothreonine binding // inferred from direct assay /// 0050816 // phosphothreonine binding // inferred from physical interaction 202928_s_at NM_024165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024165.1 /DEF=Homo sapiens PHD finger protein 1 (PHF1), transcript variant 2, mRNA. /FEA=mRNA /GEN=PHF1 /PROD=PHD finger protein 1, isoform b /DB_XREF=gi:13435396 /UG=Hs.166204 PHD finger protein 1 /FL=gb:NM_024165.1 gb:AF052205.1 NM_024165 PHD finger protein 1 PHF1 5252 NM_002636 /// NM_024165 /// NR_027692 /// XM_006715109 /// XM_006715110 /// XM_006715111 /// XM_006726097 /// XM_006726098 /// XM_006726099 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202929_s_at NM_001355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001355.2 /DEF=Homo sapiens D-dopachrome tautomerase (DDT), mRNA. /FEA=mRNA /GEN=DDT /PROD=D-dopachrome tautomerase /DB_XREF=gi:5453630 /UG=Hs.180015 D-dopachrome tautomerase /FL=gb:U84143.1 gb:U49785.1 gb:NM_001355.2 NM_001355 D-dopachrome tautomerase /// D-dopachrome tautomerase-like DDT /// DDTL 1652 /// 100037417 NM_001084392 /// NM_001084393 /// NM_001355 /// XM_005261299 /// XM_006725405 /// XM_006725406 0008152 // metabolic process // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004167 // dopachrome isomerase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0033981 // D-dopachrome decarboxylase activity // inferred from electronic annotation 202930_s_at NM_003850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003850.1 /DEF=Homo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2), mRNA. /FEA=mRNA /GEN=SUCLA2 /PROD=succinate-CoA ligase, ADP-forming, beta subunit /DB_XREF=gi:11321582 /UG=Hs.182217 succinate-CoA ligase, ADP-forming, beta subunit /FL=gb:NM_003850.1 gb:AB035863.1 NM_003850 succinate-CoA ligase, ADP-forming, beta subunit SUCLA2 8803 NM_003850 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0006781 // succinyl-CoA pathway // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004775 // succinate-CoA ligase (ADP-forming) activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202931_x_at NM_004305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004305.1 /DEF=Homo sapiens bridging integrator 1 (BIN1), mRNA. /FEA=mRNA /GEN=BIN1 /PROD=bridging integrator 1 /DB_XREF=gi:4757747 /UG=Hs.193163 bridging integrator 1 /FL=gb:U68485.1 gb:NM_004305.1 NM_004305 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 202932_at NM_005433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005433.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1), mRNA. /FEA=mRNA /GEN=YES1 /PROD=v-yes-1 Yamaguchi sarcoma viral oncogene homolog1 /DB_XREF=gi:4885660 /UG=Hs.194148 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 /FL=gb:NM_005433.1 NM_005433 YES proto-oncogene 1, Src family tyrosine kinase YES1 7525 NM_005433 /// XM_005258139 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction 202933_s_at NM_005433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005433.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1), mRNA. /FEA=mRNA /GEN=YES1 /PROD=v-yes-1 Yamaguchi sarcoma viral oncogene homolog1 /DB_XREF=gi:4885660 /UG=Hs.194148 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 /FL=gb:NM_005433.1 NM_005433 YES proto-oncogene 1, Src family tyrosine kinase YES1 7525 NM_005433 /// XM_005258139 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction 202934_at AI761561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761561 /FEA=EST /DB_XREF=gi:5177228 /DB_XREF=est:wi61h11.x1 /CLONE=IMAGE:2394789 /UG=Hs.198427 hexokinase 2 /FL=gb:NM_000189.1 gb:AF148513.1 AI761561 hexokinase 2 HK2 3099 NM_000189 /// XM_005264280 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // not recorded /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005536 // glucose binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded 202935_s_at AI382146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI382146 /FEA=EST /DB_XREF=gi:4194927 /DB_XREF=est:te30c10.x1 /CLONE=IMAGE:2087442 /UG=Hs.2316 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) /FL=gb:NM_000346.1 AI382146 SRY (sex determining region Y)-box 9 SOX9 6662 NM_000346 0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002683 // negative regulation of immune system process // inferred from sequence or structural similarity /// 0003170 // heart valve development // inferred from sequence or structural similarity /// 0003179 // heart valve morphogenesis // inferred from sequence or structural similarity /// 0003188 // heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003413 // chondrocyte differentiation involved in endochondral bone morphogenesis // inferred from mutant phenotype /// 0003415 // chondrocyte hypertrophy // inferred from sequence or structural similarity /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0019100 // male germ-line sex determination // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from expression pattern /// 0030858 // positive regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from direct assay /// 0032332 // positive regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0035622 // intrahepatic bile duct development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from expression pattern /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060221 // retinal rod cell differentiation // inferred from sequence or structural similarity /// 0060350 // endochondral bone morphogenesis // inferred from electronic annotation /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation /// 0060517 // epithelial cell proliferation involved in prostatic bud elongation // inferred from sequence or structural similarity /// 0060729 // intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0060784 // regulation of cell proliferation involved in tissue homeostasis // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0061138 // morphogenesis of a branching epithelium // inferred from sequence or structural similarity /// 0070168 // negative regulation of biomineral tissue development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0072034 // renal vesicle induction // inferred from sequence or structural similarity /// 0072170 // metanephric tubule development // inferred from electronic annotation /// 0072190 // ureter urothelium development // inferred from electronic annotation /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090184 // positive regulation of kidney development // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from direct assay /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from electronic annotation /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202936_s_at NM_000346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000346.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) (SOX9), mRNA. /FEA=mRNA /GEN=SOX9 /PROD=transcription factor SOX9 /DB_XREF=gi:4557852 /UG=Hs.2316 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) /FL=gb:NM_000346.1 NM_000346 SRY (sex determining region Y)-box 9 SOX9 6662 NM_000346 0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002683 // negative regulation of immune system process // inferred from sequence or structural similarity /// 0003170 // heart valve development // inferred from sequence or structural similarity /// 0003179 // heart valve morphogenesis // inferred from sequence or structural similarity /// 0003188 // heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003413 // chondrocyte differentiation involved in endochondral bone morphogenesis // inferred from mutant phenotype /// 0003415 // chondrocyte hypertrophy // inferred from sequence or structural similarity /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0019100 // male germ-line sex determination // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from expression pattern /// 0030858 // positive regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from direct assay /// 0032332 // positive regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0035622 // intrahepatic bile duct development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from expression pattern /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060221 // retinal rod cell differentiation // inferred from sequence or structural similarity /// 0060350 // endochondral bone morphogenesis // inferred from electronic annotation /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation /// 0060517 // epithelial cell proliferation involved in prostatic bud elongation // inferred from sequence or structural similarity /// 0060729 // intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0060784 // regulation of cell proliferation involved in tissue homeostasis // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0061138 // morphogenesis of a branching epithelium // inferred from sequence or structural similarity /// 0070168 // negative regulation of biomineral tissue development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0072034 // renal vesicle induction // inferred from sequence or structural similarity /// 0072170 // metanephric tubule development // inferred from electronic annotation /// 0072190 // ureter urothelium development // inferred from electronic annotation /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090184 // positive regulation of kidney development // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from direct assay /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from electronic annotation /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202937_x_at AL022316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022316 /DEF=Human DNA sequence from clone CTA-126B4 on chromosome 22q13.2-13.31 Contains two or three novel genes, ESTs, STSs, GSSs and a CpG Island /FEA=mRNA_3 /DB_XREF=gi:4691242 /UG=Hs.239934 CGI-96 protein /FL=gb:AF151854.1 gb:NM_015703.1 AL022316 ribosomal RNA processing 7 homolog A (S. cerevisiae) RRP7A 27341 NM_015703 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202938_x_at NM_015703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015703.1 /DEF=Homo sapiens CGI-96 protein (CGI-96), mRNA. /FEA=mRNA /GEN=CGI-96 /PROD=CGI-96 protein /DB_XREF=gi:7661545 /UG=Hs.239934 CGI-96 protein /FL=gb:AF151854.1 gb:NM_015703.1 NM_015703 ribosomal RNA processing 7 homolog A (S. cerevisiae) /// ribosomal RNA processing 7 homolog B (S. cerevisiae) RRP7A /// RRP7B 27341 /// 91695 NM_015703 /// NR_002184 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202939_at NM_005857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005857.1 /DEF=Homo sapiens zinc metalloproteinase, STE24 (yeast, homolog) (ZMPSTE24), mRNA. /FEA=mRNA /GEN=ZMPSTE24 /PROD=zinc metalloproteinase, STE24 (yeast, homolog) /DB_XREF=gi:5032128 /UG=Hs.25846 zinc metalloproteinase, STE24 (yeast, homolog) /FL=gb:AB016068.1 gb:AF064867.1 gb:NM_005857.1 NM_005857 zinc metallopeptidase STE24 ZMPSTE24 10269 NM_005857 0006508 // proteolysis // traceable author statement /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0030327 // prenylated protein catabolic process // inferred from electronic annotation /// 0071586 // CAAX-box protein processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202940_at NM_014823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014823.1 /DEF=Homo sapiens KIAA0344 gene product (KIAA0344), mRNA. /FEA=mRNA /GEN=KIAA0344 /PROD=KIAA0344 gene product /DB_XREF=gi:7662065 /UG=Hs.321444 KIAA0344 gene product /FL=gb:AB002342.1 gb:NM_014823.1 NM_014823 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay 202941_at NM_021074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021074.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) (NDUFV2), mRNA. /FEA=mRNA /GEN=NDUFV2 /PROD=NADH dehydrogenase (ubiquinone) flavoprotein 2(24kD) /DB_XREF=gi:10835024 /UG=Hs.51299 NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) /FL=gb:NM_021074.1 gb:BC001632.1 gb:M22538.1 NM_021074 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa NDUFV2 4729 NM_021074 /// XR_243808 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from mutant phenotype /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0007399 // nervous system development // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045272 // plasma membrane respiratory chain complex I // not recorded /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 202942_at NM_001985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001985.1 /DEF=Homo sapiens electron-transfer-flavoprotein, beta polypeptide (ETFB), mRNA. /FEA=mRNA /GEN=ETFB /PROD=electron-transfer-flavoprotein, betapolypeptide /DB_XREF=gi:4503608 /UG=Hs.74047 electron-transfer-flavoprotein, beta polypeptide /FL=gb:NM_001985.1 NM_001985 electron-transfer-flavoprotein, beta polypeptide ETFB 2109 NM_001014763 /// NM_001985 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation 202943_s_at M38083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M38083.1 /DEF=Human alpha-N-acetylgalactosaminidase mRNA, complete cds. /FEA=mRNA /PROD=alpha-N-acetylgalactosaminidase /DB_XREF=gi:189054 /UG=Hs.75372 N-acetylgalactosaminidase, alpha- /FL=gb:BC000095.1 gb:M62783.1 gb:M38083.1 gb:NM_000262.1 M38083 N-acetylgalactosaminidase, alpha- NAGA 4668 NM_000262 /// XM_005261615 /// XM_005261616 /// XM_005261617 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // not recorded /// 0016052 // carbohydrate catabolic process // inferred from direct assay /// 0016139 // glycoside catabolic process // not recorded /// 0019377 // glycolipid catabolic process // inferred from mutant phenotype /// 0046477 // glycosylceramide catabolic process // not recorded 0005737 // cytoplasm // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004557 // alpha-galactosidase activity // not recorded /// 0008456 // alpha-N-acetylgalactosaminidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202944_at NM_000262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000262.1 /DEF=Homo sapiens N-acetylgalactosaminidase, alpha- (NAGA), mRNA. /FEA=mRNA /GEN=NAGA /PROD=alpha-N-acetylgalactosaminidase precursor /DB_XREF=gi:4557780 /UG=Hs.75372 N-acetylgalactosaminidase, alpha- /FL=gb:BC000095.1 gb:M62783.1 gb:M38083.1 gb:NM_000262.1 NM_000262 N-acetylgalactosaminidase, alpha- NAGA 4668 NM_000262 /// XM_005261615 /// XM_005261616 /// XM_005261617 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // not recorded /// 0016052 // carbohydrate catabolic process // inferred from direct assay /// 0016139 // glycoside catabolic process // not recorded /// 0019377 // glycolipid catabolic process // inferred from mutant phenotype /// 0046477 // glycosylceramide catabolic process // not recorded 0005737 // cytoplasm // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004557 // alpha-galactosidase activity // not recorded /// 0008456 // alpha-N-acetylgalactosaminidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202945_at NM_004957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004957.1 /DEF=Homo sapiens folylpolyglutamate synthase (FPGS), mRNA. /FEA=mRNA /GEN=FPGS /PROD=folylpolyglutamate synthase /DB_XREF=gi:4826727 /UG=Hs.754 folylpolyglutamate synthase /FL=gb:M98045.1 gb:NM_004957.1 NM_004957 folylpolyglutamate synthase FPGS 2356 NM_001018078 /// NM_001288803 /// NM_004957 /// NR_110170 /// XM_005251864 /// XR_242581 /// XR_242582 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006544 // glycine metabolic process // inferred from sequence or structural similarity /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from sequence or structural similarity /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0046901 // tetrahydrofolylpolyglutamate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004326 // tetrahydrofolylpolyglutamate synthase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202946_s_at NM_014962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014962.1 /DEF=Homo sapiens KIAA0952 protein (KIAA0952), mRNA. /FEA=mRNA /GEN=KIAA0952 /PROD=KIAA0952 protein /DB_XREF=gi:7662401 /UG=Hs.7935 KIAA0952 protein /FL=gb:AB023169.1 gb:NM_014962.1 NM_014962 BTB (POZ) domain containing 3 BTBD3 22903 NM_001282550 /// NM_001282551 /// NM_001282552 /// NM_001282554 /// NM_014962 /// NM_181443 /// XM_006723550 /// XM_006723551 0007399 // nervous system development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 202947_s_at NM_002101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002101.2 /DEF=Homo sapiens glycophorin C (Gerbich blood group) (GYPC), transcript variant 1, mRNA. /FEA=mRNA /GEN=GYPC /PROD=glycophorin C, isoform 1 /DB_XREF=gi:8051606 /UG=Hs.81994 glycophorin C (Gerbich blood group) /FL=gb:M36284.1 gb:M11802.1 gb:NM_002101.2 NM_002101 glycophorin C (Gerbich blood group) GYPC 2995 NM_001256584 /// NM_002101 /// NM_016815 /// XM_005263653 /// XM_006712460 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202948_at NM_000877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000877.1 /DEF=Homo sapiens interleukin 1 receptor, type I (IL1R1), mRNA. /FEA=mRNA /GEN=IL1R1 /PROD=interleukin 1 receptor, type I /DB_XREF=gi:4504658 /UG=Hs.82112 interleukin 1 receptor, type I /FL=gb:M27492.1 gb:NM_000877.1 NM_000877 interleukin 1 receptor, type I IL1R1 3554 NM_000877 /// NM_001288706 /// XM_005263929 /// XM_005263930 /// XM_005263931 /// XM_005263932 /// XM_005263933 /// XM_005263934 /// XR_244889 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from direct assay /// 0004909 // interleukin-1, Type I, activating receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 202949_s_at NM_001450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001450.1 /DEF=Homo sapiens four and a half LIM domains 2 (FHL2), mRNA. /FEA=mRNA /GEN=FHL2 /PROD=four and a half LIM domains 2 /DB_XREF=gi:4503722 /UG=Hs.8302 four and a half LIM domains 2 /FL=gb:U29332.1 gb:NM_001450.1 NM_001450 four and a half LIM domains 2 FHL2 2274 NM_001039492 /// NM_001450 /// NM_201555 /// NM_201556 /// NM_201557 /// XM_005263901 /// XM_005263902 /// XM_005263903 /// XM_005263904 /// XM_005263906 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009725 // response to hormone // inferred from mutant phenotype /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0055014 // atrial cardiac muscle cell development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202950_at NM_001889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001889.1 /DEF=Homo sapiens crystallin, zeta (quinone reductase) (CRYZ), mRNA. /FEA=mRNA /GEN=CRYZ /PROD=crystallin, zeta (quinone reductase) /DB_XREF=gi:4503066 /UG=Hs.83114 crystallin, zeta (quinone reductase) /FL=gb:L13278.1 gb:S58039.1 gb:NM_001889.1 NM_001889 crystallin, zeta (quinone reductase) CRYZ 1429 NM_001130042 /// NM_001130043 /// NM_001134759 /// NM_001889 /// XM_005270491 0007601 // visual perception // traceable author statement /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0003960 // NADPH:quinone reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from direct assay /// 0070404 // NADH binding // inferred from direct assay 202951_at BE048506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE048506 /FEA=EST /DB_XREF=gi:8365559 /DB_XREF=est:hr49h06.x1 /CLONE=IMAGE:3131867 /UG=Hs.8724 serine threonine protein kinase /FL=gb:NM_007271.1 BE048506 serine/threonine kinase 38 STK38 11329 NM_007271 /// XM_005248839 /// XM_006714988 /// XM_006714989 /// XM_006714990 0006464 // cellular protein modification process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202952_s_at NM_003474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003474.2 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 12 (meltrin alpha) (ADAM12), transcript variant 1, mRNA. /FEA=mRNA /GEN=ADAM12 /PROD=a disintegrin and metalloprotease domain 12 ,isoform 1 preproprotein /DB_XREF=gi:13259517 /UG=Hs.8850 a disintegrin and metalloproteinase domain 12 (meltrin alpha) /FL=gb:AF023476.2 gb:NM_003474.2 NM_003474 ADAM metallopeptidase domain 12 ADAM12 8038 NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202953_at NM_000491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000491.2 /DEF=Homo sapiens complement component 1, q subcomponent, beta polypeptide (C1QB), mRNA. /FEA=mRNA /GEN=C1QB /PROD=complement component 1, q subcomponent, betapolypeptide precursor /DB_XREF=gi:11038661 /UG=Hs.8986 complement component 1, q subcomponent, beta polypeptide /FL=gb:NM_000491.2 NM_000491 complement component 1, q subcomponent, B chain C1QB 713 NM_000491 /// XM_005245982 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048839 // inner ear development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005602 // complement component C1 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202954_at NM_007019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007019.1 /DEF=Homo sapiens ubiquitin carrier protein E2-C (UBCH10), mRNA. /FEA=mRNA /GEN=UBCH10 /PROD=ubiquitin carrier protein E2-C /DB_XREF=gi:5902145 /UG=Hs.93002 ubiquitin carrier protein E2-C /FL=gb:U73379.1 gb:NM_007019.1 NM_007019 ubiquitin-conjugating enzyme E2C UBE2C 11065 NM_001281741 /// NM_001281742 /// NM_007019 /// NM_181799 /// NM_181800 /// NM_181801 /// NM_181802 /// NM_181803 /// NR_104036 /// NR_104037 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0010994 // free ubiquitin chain polymerization // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 202955_s_at AF084520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF084520.1 /DEF=Homo sapiens brefeldin A-inhibited guanine nucleotide-exchange protein 1 mRNA, complete cds. /FEA=mRNA /PROD=brefeldin A-inhibited guaninenucleotide-exchange protein 1 /DB_XREF=gi:5052120 /UG=Hs.94631 brefeldin A-inhibited guanine nucleotide-exchange protein 1 /FL=gb:AF084520.1 gb:AF111162.1 gb:NM_006421.2 AF084520 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) ARFGEF1 10565 NM_006421 /// XM_005251134 /// XM_005251135 /// XM_005251136 /// XM_006716418 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030837 // negative regulation of actin filament polymerization // inferred from mutant phenotype /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0090284 // positive regulation of protein glycosylation in Golgi // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay 202956_at NM_006421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006421.2 /DEF=Homo sapiens brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1), mRNA. /FEA=mRNA /GEN=BIG1 /PROD=brefeldin A-inhibited guaninenucleotide-exchange protein 1 /DB_XREF=gi:6715588 /UG=Hs.94631 brefeldin A-inhibited guanine nucleotide-exchange protein 1 /FL=gb:AF084520.1 gb:AF111162.1 gb:NM_006421.2 NM_006421 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) ARFGEF1 10565 NM_006421 /// XM_005251134 /// XM_005251135 /// XM_005251136 /// XM_006716418 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030837 // negative regulation of actin filament polymerization // inferred from mutant phenotype /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0090284 // positive regulation of protein glycosylation in Golgi // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay 202957_at NM_005335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005335.1 /DEF=Homo sapiens hematopoietic cell-specific Lyn substrate 1 (HCLS1), mRNA. /FEA=mRNA /GEN=HCLS1 /PROD=hematopoietic cell-specific Lyn substrate 1 /DB_XREF=gi:4885404 /UG=Hs.14601 hematopoietic cell-specific Lyn substrate 1 /FL=gb:NM_005335.1 NM_005335 hematopoietic cell-specific Lyn substrate 1 HCLS1 3059 NM_001292041 /// NM_005335 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030833 // regulation of actin filament polymerization // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202958_at NM_002833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002833.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 9 (PTPN9), mRNA. /FEA=mRNA /GEN=PTPN9 /PROD=protein tyrosine phosphatase, non-receptor type9 /DB_XREF=gi:4506300 /UG=Hs.147663 protein tyrosine phosphatase, non-receptor type 9 /FL=gb:M83738.1 gb:NM_002833.1 NM_002833 protein tyrosine phosphatase, non-receptor type 9 PTPN9 5780 NM_002833 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 202959_at AI433712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI433712 /FEA=EST /DB_XREF=gi:4291098 /DB_XREF=est:ti88f08.x1 /CLONE=IMAGE:2139111 /UG=Hs.155212 methylmalonyl Coenzyme A mutase /FL=gb:M65131.1 gb:NM_000255.1 AI433712 methylmalonyl CoA mutase MUT 4594 NM_000255 /// XM_005249143 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004494 // methylmalonyl-CoA mutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 202960_s_at NM_000255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000255.1 /DEF=Homo sapiens methylmalonyl Coenzyme A mutase (MUT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MUT /PROD=methylmalonyl Coenzyme A mutase precursor /DB_XREF=gi:4557766 /UG=Hs.155212 methylmalonyl Coenzyme A mutase /FL=gb:M65131.1 gb:NM_000255.1 NM_000255 methylmalonyl CoA mutase MUT 4594 NM_000255 /// XM_005249143 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004494 // methylmalonyl-CoA mutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 202961_s_at NM_004889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004889.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 (ATP5J2), mRNA. /FEA=mRNA /GEN=ATP5J2 /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit f, isoform 2 /DB_XREF=gi:4757811 /UG=Hs.155751 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 /FL=gb:BC003678.1 gb:AF047436.1 gb:NM_004889.1 NM_004889 ARMC2 antisense RNA 1 /// ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 ARMC2-AS1 /// ATP5J2 9551 /// 101929716 NM_001003713 /// NM_001003714 /// NM_001039178 /// NM_001190353 /// NM_001190354 /// NM_004889 /// NR_104137 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 202962_at NM_015254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015254.1 /DEF=Homo sapiens kinesin family member 13B (KIF13B), mRNA. /FEA=mRNA /GEN=KIF13B /PROD=kinesin family member 13B /DB_XREF=gi:13194196 /UG=Hs.15711 kinesin family member 13B /FL=gb:AL583912.1 gb:NM_015254.1 gb:AF279865.1 NM_015254 kinesin family member 13B KIF13B 23303 NM_015254 /// XM_005273458 /// XM_005273459 /// XM_006716316 /// XM_006716317 0006605 // protein targeting // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0050770 // regulation of axonogenesis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 202963_at AW027312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027312 /FEA=EST /DB_XREF=gi:5886068 /DB_XREF=est:wt73b04.x1 /CLONE=IMAGE:2513071 /UG=Hs.166891 regulatory factor X, 5 (influences HLA class II expression) /FL=gb:NM_000449.1 AW027312 regulatory factor X, 5 (influences HLA class II expression) RFX5 5993 NM_000449 /// NM_001025603 /// XM_005245405 /// XM_005245406 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202964_s_at NM_000449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000449.1 /DEF=Homo sapiens regulatory factor X, 5 (influences HLA class II expression) (RFX5), mRNA. /FEA=mRNA /GEN=RFX5 /PROD=regulatory factor X, 5 /DB_XREF=gi:4557842 /UG=Hs.166891 regulatory factor X, 5 (influences HLA class II expression) /FL=gb:NM_000449.1 NM_000449 regulatory factor X, 5 (influences HLA class II expression) RFX5 5993 NM_000449 /// NM_001025603 /// XM_005245405 /// XM_005245406 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202965_s_at NM_014289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014289.2 /DEF=Homo sapiens calpain 6 (CAPN6), mRNA. /FEA=mRNA /GEN=CAPN6 /PROD=calpain 6 /DB_XREF=gi:13186315 /UG=Hs.169172 calpain 6 /FL=gb:BC000730.1 gb:NM_014289.2 gb:AF029232.1 NM_014289 calpain 6 CAPN6 827 NM_014289 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0006508 // proteolysis // not recorded /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 202966_at NM_014289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014289.2 /DEF=Homo sapiens calpain 6 (CAPN6), mRNA. /FEA=mRNA /GEN=CAPN6 /PROD=calpain 6 /DB_XREF=gi:13186315 /UG=Hs.169172 calpain 6 /FL=gb:BC000730.1 gb:NM_014289.2 gb:AF029232.1 NM_014289 calpain 6 CAPN6 827 NM_014289 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0006508 // proteolysis // not recorded /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 202967_at NM_001512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001512.1 /DEF=Homo sapiens glutathione S-transferase A4 (GSTA4), mRNA. /FEA=mRNA /GEN=GSTA4 /PROD=glutathione S-transferase A4 /DB_XREF=gi:4504172 /UG=Hs.169907 glutathione S-transferase A4 /FL=gb:AF020918.1 gb:AF025887.1 gb:NM_001512.1 gb:AF125271.1 gb:AF125272.1 gb:AF125273.1 NM_001512 glutathione S-transferase alpha 4 GSTA4 2941 NM_001512 /// XM_005249035 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202968_s_at Y09216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09216.1 /DEF=H.sapiens mRNA for protein kinase, Dyrk2. /FEA=mRNA /GEN=Dyrk2 /DB_XREF=gi:1666065 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 Y09216 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 202969_at AI216690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI216690 /FEA=EST /DB_XREF=gi:3785731 /DB_XREF=est:qg66h07.x1 /CLONE=IMAGE:1840189 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 AI216690 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 202970_at AI192838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI192838 /FEA=EST /DB_XREF=gi:3744047 /DB_XREF=est:qe63c04.x1 /CLONE=IMAGE:1743654 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 AI192838 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 202971_s_at NM_006482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006482.1 /DEF=Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), transcript variant 2, mRNA. /FEA=mRNA /GEN=DYRK2 /PROD=dual-specificity tyrosine-(Y)-phosphorylationregulated kinase 2 isoform 2 /DB_XREF=gi:5922003 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 NM_006482 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 202972_s_at AW450403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450403 /FEA=EST /DB_XREF=gi:6991179 /DB_XREF=est:UI-H-BI3-akn-g-07-0-UI.s1 /CLONE=IMAGE:2735029 /UG=Hs.177664 KIAA0914 gene product /FL=gb:AB020721.1 gb:NM_014883.1 AW450403 family with sequence similarity 13, member A FAM13A 10144 NM_001015045 /// NM_001265578 /// NM_001265579 /// NM_001265580 /// NM_014883 /// XM_005262681 /// XM_005262682 /// XM_005262683 /// XM_005262684 /// XM_005262685 /// XM_006714057 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 202973_x_at NM_014883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014883.1 /DEF=Homo sapiens KIAA0914 gene product (KIAA0914), mRNA. /FEA=mRNA /GEN=KIAA0914 /PROD=KIAA0914 gene product /DB_XREF=gi:7662375 /UG=Hs.177664 KIAA0914 gene product /FL=gb:AB020721.1 gb:NM_014883.1 NM_014883 family with sequence similarity 13, member A FAM13A 10144 NM_001015045 /// NM_001265578 /// NM_001265579 /// NM_001265580 /// NM_014883 /// XM_005262681 /// XM_005262682 /// XM_005262683 /// XM_005262684 /// XM_005262685 /// XM_006714057 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 202974_at NM_002436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002436.2 /DEF=Homo sapiens membrane protein, palmitoylated 1 (55kD) (MPP1), mRNA. /FEA=mRNA /GEN=MPP1 /PROD=palmitoylated membrane protein 1 /DB_XREF=gi:6006024 /UG=Hs.1861 membrane protein, palmitoylated 1 (55kD) /FL=gb:BC002392.1 gb:M64925.1 gb:NM_002436.2 NM_002436 membrane protein, palmitoylated 1, 55kDa MPP1 4354 NM_001166460 /// NM_001166461 /// NM_001166462 /// NM_002436 0007165 // signal transduction // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0090022 // regulation of neutrophil chemotaxis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202975_s_at N21138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21138 /FEA=EST /DB_XREF=gi:1126308 /DB_XREF=est:yx52h03.s1 /CLONE=IMAGE:265397 /UG=Hs.188006 KIAA0878 protein /FL=gb:AB020685.1 gb:NM_014899.1 N21138 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 202976_s_at NM_014899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014899.1 /DEF=Homo sapiens KIAA0878 protein (KIAA0878), mRNA. /FEA=mRNA /GEN=KIAA0878 /PROD=KIAA0878 protein /DB_XREF=gi:7662355 /UG=Hs.188006 KIAA0878 protein /FL=gb:AB020685.1 gb:NM_014899.1 NM_014899 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 202977_s_at AI206560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI206560 /FEA=EST /DB_XREF=gi:3765232 /DB_XREF=est:qf61g11.x1 /CLONE=IMAGE:1754564 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1 AI206560 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202978_s_at AW204564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW204564 /FEA=EST /DB_XREF=gi:6504036 /DB_XREF=est:UI-H-BI1-aec-e-07-0-UI.s1 /CLONE=IMAGE:2718828 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1 AW204564 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202979_s_at NM_021212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021212.1 /DEF=Homo sapiens HCF-binding transcription factor Zhangfei (ZF), mRNA. /FEA=mRNA /GEN=ZF /PROD=HCF-binding transcription factor Zhangfei /DB_XREF=gi:10864024 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1 NM_021212 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202980_s_at AI953523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI953523 /FEA=EST /DB_XREF=gi:5745833 /DB_XREF=est:wq29g12.x1 /CLONE=IMAGE:2472742 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 /FL=gb:U76247.1 gb:U63295.1 gb:NM_003031.1 AI953523 siah E3 ubiquitin protein ligase 1 SIAH1 6477 NM_001006610 /// NM_003031 /// XM_006721246 0006200 // ATP catabolic process // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006515 // misfolded or incompletely synthesized protein catabolic process // /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // /// 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202981_x_at NM_003031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003031.1 /DEF=Homo sapiens seven in absentia (Drosophila) homolog 1 (SIAH1), mRNA. /FEA=mRNA /GEN=SIAH1 /PROD=seven in absentia (Drosophila) homolog 1 /DB_XREF=gi:4506946 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 /FL=gb:U76247.1 gb:U63295.1 gb:NM_003031.1 NM_003031 siah E3 ubiquitin protein ligase 1 SIAH1 6477 NM_001006610 /// NM_003031 /// XM_006721246 0006200 // ATP catabolic process // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006515 // misfolded or incompletely synthesized protein catabolic process // /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // /// 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202982_s_at NM_006821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006821.1 /DEF=Homo sapiens peroxisomal long-chain acyl-coA thioesterase (ZAP128), mRNA. /FEA=mRNA /GEN=ZAP128 /PROD=peroxisomal long-chain acyl-coA thioesterase /DB_XREF=gi:13375613 /UG=Hs.299629 peroxisomal long-chain acyl-coA thioesterase /FL=gb:BC004436.1 gb:NM_006821.1 gb:AY005822.1 NM_006821 acyl-CoA thioesterase 1 /// acyl-CoA thioesterase 2 ACOT1 /// ACOT2 10965 /// 641371 NM_001037161 /// NM_006821 /// NR_046028 /// XM_006720007 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006637 // acyl-CoA metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay 202983_at AI760760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760760 /FEA=EST /DB_XREF=gi:5176427 /DB_XREF=est:wi67b09.x1 /CLONE=IMAGE:2398361 /UG=Hs.3068 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 /FL=gb:NM_003071.1 AI760760 helicase-like transcription factor HLTF 6596 NM_003071 /// NM_139048 /// XM_005247724 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202984_s_at AA457021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA457021 /FEA=EST /DB_XREF=gi:2179741 /DB_XREF=est:aa38a08.s1 /CLONE=IMAGE:815510 /UG=Hs.5443 BCL2-associated athanogene 5 /FL=gb:AF095195.2 gb:NM_004873.1 AA457021 BCL2-associated athanogene 5 BAG5 9529 NM_001015048 /// NM_001015049 /// NM_004873 0006457 // protein folding // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0061084 // negative regulation of protein refolding // inferred from sequence or structural similarity /// 0070997 // neuron death // inferred from sequence or structural similarity /// 0090083 // regulation of inclusion body assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 202985_s_at NM_004873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004873.1 /DEF=Homo sapiens BCL2-associated athanogene 5 (BAG5), mRNA. /FEA=mRNA /GEN=BAG5 /PROD=BCL2-associated athanogene 5 /DB_XREF=gi:6631076 /UG=Hs.5443 BCL2-associated athanogene 5 /FL=gb:AF095195.2 gb:NM_004873.1 NM_004873 BCL2-associated athanogene 5 BAG5 9529 NM_001015048 /// NM_001015049 /// NM_004873 0006457 // protein folding // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0061084 // negative regulation of protein refolding // inferred from sequence or structural similarity /// 0070997 // neuron death // inferred from sequence or structural similarity /// 0090083 // regulation of inclusion body assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 202986_at NM_014862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014862.1 /DEF=Homo sapiens KIAA0307 gene product (KIAA0307), mRNA. /FEA=mRNA /GEN=KIAA0307 /PROD=KIAA0307 gene product /DB_XREF=gi:7662049 /UG=Hs.6111 KIAA0307 gene product /FL=gb:AB002305.1 gb:NM_014862.1 NM_014862 aryl-hydrocarbon receptor nuclear translocator 2 ARNT2 9915 NM_014862 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017162 // aryl hydrocarbon receptor binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 202987_at AW296296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW296296 /FEA=EST /DB_XREF=gi:6702922 /DB_XREF=est:UI-H-BI2-aid-c-12-0-UI.s1 /CLONE=IMAGE:2728727 /UG=Hs.7446 DKFZP586G0522 protein /FL=gb:AF274303.1 gb:AF272151.1 gb:BC002823.1 gb:AL050289.1 gb:NM_015524.1 AW296296 TRAF3 interacting protein 2 TRAF3IP2 10758 NM_001164281 /// NM_001164282 /// NM_001164283 /// NM_147200 /// NM_147686 /// NR_028338 /// XM_006715319 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0048305 // immunoglobulin secretion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202988_s_at NM_002922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002922.1 /DEF=Homo sapiens regulator of G-protein signalling 1 (RGS1), mRNA. /FEA=mRNA /GEN=RGS1 /PROD=regulator of G-protein signalling 1 /DB_XREF=gi:4506514 /UG=Hs.75256 regulator of G-protein signalling 1 /FL=gb:NM_002922.1 NM_002922 regulator of G-protein signaling 1 RGS1 5996 NM_002922 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 202989_at NM_002922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002922.1 /DEF=Homo sapiens regulator of G-protein signalling 1 (RGS1), mRNA. /FEA=mRNA /GEN=RGS1 /PROD=regulator of G-protein signalling 1 /DB_XREF=gi:4506514 /UG=Hs.75256 regulator of G-protein signalling 1 /FL=gb:NM_002922.1 NM_002922 regulator of G-protein signaling 1 RGS1 5996 NM_002922 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 202990_at NM_002863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002863.1 /DEF=Homo sapiens phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) (PYGL), mRNA. /FEA=mRNA /GEN=PYGL /PROD=phosphorylase, glycogen; liver (Hers disease,glycogen storage disease type VI) /DB_XREF=gi:4506352 /UG=Hs.771 phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) /FL=gb:M14636.1 gb:AF066858.1 gb:AF046785.1 gb:NM_002863.1 NM_002863 phosphorylase, glycogen, liver PYGL 5836 NM_001163940 /// NM_002863 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from mutant phenotype /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002060 // purine nucleobase binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005536 // glucose binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0008184 // glycogen phosphorylase activity // not recorded /// 0008184 // glycogen phosphorylase activity // inferred from direct assay /// 0008184 // glycogen phosphorylase activity // inferred from mutant phenotype /// 0016208 // AMP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019842 // vitamin binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032052 // bile acid binding // inferred from direct assay /// 0042803 // protein homodimerization activity // non-traceable author statement 202991_at NM_006804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006804.1 /DEF=Homo sapiens steroidogenic acute regulatory protein related (MLN64), mRNA. /FEA=mRNA /GEN=MLN64 /PROD=steroidogenic acute regulatory protein related /DB_XREF=gi:5803089 /UG=Hs.77628 steroidogenic acute regulatory protein related /FL=gb:D38255.1 gb:NM_006804.1 NM_006804 StAR-related lipid transfer (START) domain containing 3 STARD3 10948 NM_001165937 /// NM_001165938 /// NM_006804 /// XM_006721645 /// XM_006721646 /// XR_243628 /// XR_429868 0006629 // lipid metabolic process // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006701 // progesterone biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation 202992_at NM_000587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000587.1 /DEF=Homo sapiens complement component 7 (C7), mRNA. /FEA=mRNA /GEN=C7 /PROD=complement component 7 precursor /DB_XREF=gi:4557386 /UG=Hs.78065 complement component 7 /FL=gb:J03507.1 gb:NM_000587.1 NM_000587 complement component 7 C7 730 NM_000587 0002376 // immune system process // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202993_at NM_006844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006844.1 /DEF=Homo sapiens ilvB (bacterial acetolactate synthase)-like (ILVBL), mRNA. /FEA=mRNA /GEN=ILVBL /PROD=ilvB (bacterial acetolactate synthase)-like /DB_XREF=gi:5803041 /UG=Hs.78880 ilvB (bacterial acetolactate synthase)-like /FL=gb:U61263.1 gb:NM_006844.1 NM_006844 ilvB (bacterial acetolactate synthase)-like ILVBL 10994 NM_006844 /// NM_176826 /// XM_005259717 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202994_s_at Z95331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z95331 /DEF=Human DNA sequence from clone CTA-941F9 on chromosome 22q13 Contains the 3 end of the FBLN1 gene for Fibulin 1 isoforms B, C and D, the first exon of the gene for a novel protein (the ortholog of mouse brain protein E46), ESTs, STSs, GSSs and two... /FEA=mRNA_1 /DB_XREF=gi:6572282 /UG=Hs.79732 fibulin 1 /FL=gb:U01244.1 gb:NM_006486.1 Z95331 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 202995_s_at NM_006486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006486.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant D, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform D /DB_XREF=gi:5922008 /UG=Hs.79732 fibulin 1 /FL=gb:U01244.1 gb:NM_006486.1 NM_006486 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 202996_at NM_021173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021173.1 /DEF=Homo sapiens polymerase (DNA-directed), delta 4 (POLD4), mRNA. /FEA=mRNA /GEN=POLD4 /PROD=polymerase (DNA-directed), delta 4 /DB_XREF=gi:10863968 /UG=Hs.82520 polymerase (DNA-directed), delta 4 /FL=gb:NM_021173.1 gb:BC001334.1 gb:AF179890.1 NM_021173 polymerase (DNA-directed), delta 4, accessory subunit POLD4 57804 NM_001256870 /// NM_021173 /// NR_046411 /// NR_046412 /// NR_046413 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 202997_s_at BE251211 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE251211 /FEA=EST /DB_XREF=gi:9121333 /DB_XREF=est:601116312F1 /CLONE=IMAGE:3356954 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1 BE251211 lysyl oxidase-like 2 LOXL2 4017 NM_002318 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay 202998_s_at NM_002318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002318.1 /DEF=Homo sapiens lysyl oxidase-like 2 (LOXL2), mRNA. /FEA=mRNA /GEN=LOXL2 /PROD=lysyl oxidase-like 2 /DB_XREF=gi:4505010 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1 NM_002318 lysyl oxidase-like 2 LOXL2 4017 NM_002318 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay 202999_s_at AF117949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF117949.1 /DEF=Homo sapiens lysyl oxidase-like protein 2 (LOXL2) mRNA, complete cds. /FEA=mRNA /GEN=LOXL2 /PROD=lysyl oxidase-like protein 2 /DB_XREF=gi:4959424 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1 AF117949 lysyl oxidase-like 2 LOXL2 4017 NM_002318 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay 203000_at BF967657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF967657 /FEA=EST /DB_XREF=gi:12334872 /DB_XREF=est:602287358T1 /CLONE=IMAGE:4374495 /UG=Hs.90005 superiorcervical ganglia, neural specific 10 /FL=gb:D50375.1 gb:NM_007029.1 BF967657 stathmin 2 STMN2 11075 NM_001199214 /// NM_007029 /// XM_005251142 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030182 // neuron differentiation // non-traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031117 // positive regulation of microtubule depolymerization // inferred from direct assay /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 203001_s_at NM_007029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007029.1 /DEF=Homo sapiens superiorcervical ganglia, neural specific 10 (SCGN10), mRNA. /FEA=mRNA /GEN=SCGN10 /PROD=superiorcervical ganglia, neural specific 10 /DB_XREF=gi:5902079 /UG=Hs.90005 superiorcervical ganglia, neural specific 10 /FL=gb:D50375.1 gb:NM_007029.1 NM_007029 stathmin 2 STMN2 11075 NM_001199214 /// NM_007029 /// XM_005251142 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030182 // neuron differentiation // non-traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031117 // positive regulation of microtubule depolymerization // inferred from direct assay /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 203002_at NM_016201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016201.1 /DEF=Homo sapiens Leman coiled-coil protein (LCCP), mRNA. /FEA=mRNA /GEN=LCCP /PROD=Leman coiled-coil protein /DB_XREF=gi:7705577 /UG=Hs.92186 Leman coiled-coil protein /FL=gb:AF175966.1 gb:NM_016201.1 NM_016201 angiomotin like 2 AMOTL2 51421 NM_001278683 /// NM_001278685 /// NM_016201 /// XM_005247520 /// XM_006713654 /// XM_006713655 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 203003_at AL530331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL530331 /FEA=EST /DB_XREF=gi:12793824 /DB_XREF=est:AL530331 /CLONE=CS0DD007YM06 (3 prime) /UG=Hs.111243 MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) /FL=gb:L16794.1 gb:NM_005920.1 AL530331 myocyte enhancer factor 2D MEF2D 4209 NM_001271629 /// NM_005920 /// XM_005245169 /// XM_005245170 /// XM_006711330 /// XM_006711331 /// XM_006711332 /// XM_006711333 /// XM_006711334 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from expression pattern /// 0007517 // muscle organ development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 203004_s_at NM_005920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005920.1 /DEF=Homo sapiens MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D), mRNA. /FEA=mRNA /GEN=MEF2D /PROD=MADS box transcription enhancer factor 2,polypeptide D (myocyte enhancer factor 2D) /DB_XREF=gi:5174544 /UG=Hs.111243 MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) /FL=gb:L16794.1 gb:NM_005920.1 NM_005920 myocyte enhancer factor 2D MEF2D 4209 NM_001271629 /// NM_005920 /// XM_005245169 /// XM_005245170 /// XM_006711330 /// XM_006711331 /// XM_006711332 /// XM_006711333 /// XM_006711334 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from expression pattern /// 0007517 // muscle organ development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 203005_at NM_002342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002342.1 /DEF=Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3 (LTBR), mRNA. /FEA=mRNA /GEN=LTBR /PROD=lymphotoxin B receptor /DB_XREF=gi:4505038 /UG=Hs.1116 lymphotoxin beta receptor (TNFR superfamily, member 3 /FL=gb:L04270.1 gb:NM_002342.1 NM_002342 lymphotoxin beta receptor (TNFR superfamily, member 3) LTBR 4055 NM_001270987 /// NM_002342 /// XM_005253688 /// XM_006718983 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 203006_at NM_005539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005539.1 /DEF=Homo sapiens inositol polyphosphate-5-phosphatase, 40kD (INPP5A), mRNA. /FEA=mRNA /GEN=INPP5A /PROD=inositol polyphosphate-5-phosphatase, 40kD /DB_XREF=gi:5031796 /UG=Hs.124029 inositol polyphosphate-5-phosphatase, 40kD /FL=gb:NM_005539.1 NM_005539 inositol polyphosphate-5-phosphatase, 40kDa INPP5A 3632 NM_005539 0007154 // cell communication // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004445 // inositol-polyphosphate 5-phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from physical interaction /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation 203007_x_at AF077198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077198.1 /DEF=Homo sapiens lysophospholipase mRNA, complete cds. /FEA=mRNA /PROD=lysophospholipase /DB_XREF=gi:4679009 /UG=Hs.12540 lysophospholipase I /FL=gb:AF081281.1 gb:AF077198.1 gb:NM_006330.1 gb:AF291053.1 AF077198 lysophospholipase I LYPLA1 10434 NM_001279356 /// NM_001279357 /// NM_001279358 /// NM_001279359 /// NM_001279360 /// NM_006330 /// XM_005251127 /// XM_006716417 /// XR_428339 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004622 // lysophospholipase activity // traceable author statement /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203008_x_at NM_005783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005783.1 /DEF=Homo sapiens ATP binding protein associated with cell differentiation (APACD), mRNA. /FEA=mRNA /GEN=APACD /PROD=ATP binding protein associated with celldifferentiation /DB_XREF=gi:5031582 /UG=Hs.153884 ATP binding protein associated with cell differentiation /FL=gb:AB006679.1 gb:NM_005783.1 NM_005783 thioredoxin domain containing 9 TXNDC9 10190 NM_005783 0045454 // cell redox homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203009_at NM_005581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005581.1 /DEF=Homo sapiens Lutheran blood group (Auberger b antigen included) (LU), mRNA. /FEA=mRNA /GEN=LU /PROD=Lutheran blood group (Auberger b antigenincluded) /DB_XREF=gi:5031890 /UG=Hs.155048 Lutheran blood group (Auberger b antigen included) /FL=gb:NM_005581.1 NM_005581 basal cell adhesion molecule (Lutheran blood group) BCAM 4059 NM_001013257 /// NM_005581 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005055 // laminin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from mutant phenotype 203010_at NM_003152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003152.1 /DEF=Homo sapiens signal transducer and activator of transcription 5A (STAT5A), mRNA. /FEA=mRNA /GEN=STAT5A /PROD=signal transducer and activator of transcription5A /DB_XREF=gi:4507256 /UG=Hs.167503 signal transducer and activator of transcription 5A /FL=gb:U43185.1 gb:NM_003152.1 gb:L41142.1 NM_003152 signal transducer and activator of transcription 5A STAT5A 6776 NM_001288718 /// NM_001288719 /// NM_001288720 /// NM_003152 /// XM_005257624 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0001553 // luteinization // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046543 // development of secondary female sexual characteristics // inferred from electronic annotation /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0060376 // positive regulation of mast cell differentiation // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0070668 // positive regulation of mast cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203011_at NM_005536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005536.2 /DEF=Homo sapiens inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1), mRNA. /FEA=mRNA /GEN=IMPA1 /PROD=inositol(myo)-1(or 4)-monophosphatase 1 /DB_XREF=gi:8393607 /UG=Hs.171776 inositol(myo)-1(or 4)-monophosphatase 1 /FL=gb:AF042729.2 gb:NM_005536.2 NM_005536 inositol(myo)-1(or 4)-monophosphatase 1 IMPA1 3612 NM_001144878 /// NM_001144879 /// NM_005536 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006661 // phosphatidylinositol biosynthetic process // inferred from mutant phenotype /// 0006796 // phosphate-containing compound metabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008934 // inositol monophosphate 1-phosphatase activity // inferred from direct assay /// 0008934 // inositol monophosphate 1-phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation 203012_x_at NM_000984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000984.1 /DEF=Homo sapiens ribosomal protein L23a (RPL23A), mRNA. /FEA=mRNA /GEN=RPL23A /PROD=ribosomal protein L23a /DB_XREF=gi:4506614 /UG=Hs.184776 ribosomal protein L23a /FL=gb:U37230.1 gb:NM_000984.1 NM_000984 ribosomal protein L23a RPL23A 6147 NM_000984 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203013_at NM_007265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007265.1 /DEF=Homo sapiens suppressor of S. cerevisiae gcr2 (HSGT1), mRNA. /FEA=mRNA /GEN=HSGT1 /PROD=suppressor of S. cerevisiae gcr2 /DB_XREF=gi:6005783 /UG=Hs.19673 suppressor of S. cerevisiae gcr2 /FL=gb:BC000721.1 gb:D88208.1 gb:NM_007265.1 NM_007265 ecdysoneless homolog (Drosophila) ECD 11319 NM_001135752 /// NM_001135753 /// NM_007265 /// NR_024203 0006110 // regulation of glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203014_x_at NM_015705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015705.1 /DEF=Homo sapiens hypothetical protein (DJ1042K10.2), mRNA. /FEA=mRNA /GEN=DJ1042K10.2 /PROD=hypothetical protein /DB_XREF=gi:11034850 /UG=Hs.22129 hypothetical protein /FL=gb:NM_015705.1 NM_015705 small G protein signaling modulator 3 SGSM3 27352 NM_015705 /// XM_005261572 /// XM_005261573 /// XM_005261574 /// XM_005261575 /// XM_005261577 /// XM_005261579 /// XR_244369 /// XR_244370 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032483 // regulation of Rab protein signal transduction // inferred from expression pattern /// 0032486 // Rap protein signal transduction // inferred from expression pattern /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from direct assay 203015_s_at AW136988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW136988 /FEA=EST /DB_XREF=gi:6141121 /DB_XREF=est:UI-H-BI1-acu-b-04-0-UI.s1 /CLONE=IMAGE:2715582 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 AW136988 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203016_s_at AK001710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001710.1 /DEF=Homo sapiens cDNA FLJ10848 fis, clone NT2RP4001407, highly similar to Homo sapiens mRNA for KIAA0923 protein. /FEA=mRNA /DB_XREF=gi:7023139 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 AK001710 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203017_s_at R52678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R52678 /FEA=EST /DB_XREF=gi:814580 /DB_XREF=est:yg99c07.s1 /CLONE=IMAGE:41738 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 R52678 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203018_s_at AU152583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152583 /FEA=EST /DB_XREF=gi:11014104 /DB_XREF=est:AU152583 /CLONE=NT2RP3001245 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 AU152583 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203019_x_at NM_014021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014021.1 /DEF=Homo sapiens KIAA0923 protein (KIAA0923), mRNA. /FEA=mRNA /GEN=KIAA0923 /PROD=KIAA0923 protein /DB_XREF=gi:7662381 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 NM_014021 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203020_at NM_014857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014857.1 /DEF=Homo sapiens KIAA0471 gene product (KIAA0471), mRNA. /FEA=mRNA /GEN=KIAA0471 /PROD=KIAA0471 gene product /DB_XREF=gi:7662143 /UG=Hs.242271 KIAA0471 gene product /FL=gb:AB007940.1 gb:NM_014857.1 NM_014857 RAB GTPase activating protein 1-like RABGAP1L 9910 NM_001035230 /// NM_001243763 /// NM_001243764 /// NM_001243765 /// NM_014857 /// XM_005245680 /// XM_005245681 /// XM_006711692 /// XM_006711693 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from direct assay 203021_at NM_003064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003064.1 /DEF=Homo sapiens secretory leukocyte protease inhibitor (antileukoproteinase) (SLPI), mRNA. /FEA=mRNA /GEN=SLPI /PROD=secretory leukocyte protease inhibitor(antileukoproteinase) /DB_XREF=gi:4507064 /UG=Hs.251754 secretory leukocyte protease inhibitor (antileukoproteinase) /FL=gb:NM_003066.1 gb:AF114471.1 gb:NM_003064.1 NM_003064 secretory leukocyte peptidase inhibitor SLPI 6590 NM_003064 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203022_at NM_006397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006397.1 /DEF=Homo sapiens ribonuclease HI, large subunit (RNASEHI), mRNA. /FEA=mRNA /GEN=RNASEHI /PROD=ribonuclease HI, large subunit /DB_XREF=gi:5454009 /UG=Hs.25292 ribonuclease HI, large subunit /FL=gb:NM_006397.1 NM_006397 ribonuclease H2, subunit A RNASEH2A 10535 NM_006397 /// XM_006722619 0006260 // DNA replication // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006401 // RNA catabolic process // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0032299 // ribonuclease H2 complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from direct assay /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203023_at NM_016391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016391.1 /DEF=Homo sapiens hypothetical protein (HSPC111), mRNA. /FEA=mRNA /GEN=HSPC111 /PROD=hypothetical protein /DB_XREF=gi:7705450 /UG=Hs.279918 hypothetical protein /FL=gb:AF151875.1 gb:AF161460.1 gb:AF151019.1 gb:NM_016391.1 NM_016391 NOP16 nucleolar protein NOP16 51491 NM_001256539 /// NM_001256540 /// NM_001291305 /// NM_001291306 /// NM_001291307 /// NM_001291308 /// NM_016391 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 203024_s_at NM_020199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020199.1 /DEF=Homo sapiens HTGN29 protein (HTGN29), mRNA. /FEA=mRNA /GEN=HTGN29 /PROD=HTGN29 protein /DB_XREF=gi:9910277 /UG=Hs.283437 HTGN29 protein /FL=gb:AF226055.1 gb:NM_020199.1 NM_020199 chromosome 5 open reading frame 15 C5orf15 56951 NM_020199 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203025_at NM_003491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003491.1 /DEF=Homo sapiens N-acetyltransferase, homolog of S. cerevisiae ARD1 (ARD1), mRNA. /FEA=mRNA /GEN=ARD1 /PROD=N-acetyltransferase, homolog of S. cerevisiaeARD1 /DB_XREF=gi:10835056 /UG=Hs.333034 N-acetyltransferase, homolog of S. cerevisiae ARD1 /FL=gb:NM_003491.1 gb:BC000308.1 NM_003491 N(alpha)-acetyltransferase 10, NatA catalytic subunit NAA10 8260 NM_001256119 /// NM_001256120 /// NM_003491 0006323 // DNA packaging // traceable author statement /// 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay /// 0006475 // internal protein amino acid acetylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031415 // NatA complex // inferred from direct assay 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // traceable author statement /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from direct assay 203026_at NM_014872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014872.1 /DEF=Homo sapiens KIAA0354 gene product (KIAA0354), mRNA. /FEA=mRNA /GEN=KIAA0354 /PROD=KIAA0354 gene product /DB_XREF=gi:7662073 /UG=Hs.3682 KIAA0354 gene product /FL=gb:AB002352.1 gb:NM_014872.1 NM_014872 zinc finger and BTB domain containing 5 ZBTB5 9925 NM_014872 /// XM_005251634 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203027_s_at AI189359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189359 /FEA=EST /DB_XREF=gi:3740568 /DB_XREF=est:qd05f07.x1 /CLONE=IMAGE:1722853 /UG=Hs.3828 mevalonate (diphospho) decarboxylase /FL=gb:U49260.1 gb:BC000011.1 gb:NM_002461.1 AI189359 mevalonate (diphospho) decarboxylase MVD 4597 NM_002461 /// XM_005256312 /// XM_006721192 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004163 // diphosphomevalonate decarboxylase activity // inferred from direct assay /// 0004163 // diphosphomevalonate decarboxylase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 203028_s_at NM_000101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000101.1 /DEF=Homo sapiens cytochrome b-245, alpha polypeptide (CYBA), mRNA. /FEA=mRNA /GEN=CYBA /PROD=flavocytochrome b-558 alpha polypeptide /DB_XREF=gi:4557504 /UG=Hs.68877 cytochrome b-245, alpha polypeptide /FL=gb:M21186.1 gb:NM_000101.1 NM_000101 cytochrome b-245, alpha polypeptide CYBA 1535 NM_000101 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0003106 // negative regulation of glomerular filtration by angiotensin // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014895 // smooth muscle hypertrophy // inferred from sequence or structural similarity /// 0017004 // cytochrome complex assembly // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0050665 // hydrogen peroxide biosynthetic process // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // inferred from mutant phenotype /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203029_s_at NM_002847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002847.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), mRNA. /FEA=mRNA /GEN=PTPRN2 /PROD=protein tyrosine phosphatase, receptor type, Npolypeptide 2 /DB_XREF=gi:11386148 /UG=Hs.74624 protein tyrosine phosphatase, receptor type, N polypeptide 2 /FL=gb:NM_002847.1 gb:U66702.1 gb:AF007555.1 NM_002847 protein tyrosine phosphatase, receptor type, N polypeptide 2 PTPRN2 5799 NM_002847 /// NM_130842 /// NM_130843 /// XM_006716075 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203030_s_at AF007555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF007555.1 /DEF=Homo sapiens IARreceptor-like protein-tyrosine phosphatase precursor mRNA, complete cds. /FEA=mRNA /PROD=IARreceptor-like protein-tyrosine phosphataseprecursor /DB_XREF=gi:2262074 /UG=Hs.74624 protein tyrosine phosphatase, receptor type, N polypeptide 2 /FL=gb:NM_002847.1 gb:U66702.1 gb:AF007555.1 AF007555 protein tyrosine phosphatase, receptor type, N polypeptide 2 PTPRN2 5799 NM_002847 /// NM_130842 /// NM_130843 /// XM_006716075 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203031_s_at NM_000375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000375.1 /DEF=Homo sapiens uroporphyrinogen III synthase (congenital erythropoietic porphyria) (UROS), mRNA. /FEA=mRNA /GEN=UROS /PROD=uroporphyrinogen III synthase /DB_XREF=gi:4557872 /UG=Hs.75593 uroporphyrinogen III synthase (congenital erythropoietic porphyria) /FL=gb:BC002573.1 gb:J03824.1 gb:NM_000375.1 NM_000375 uroporphyrinogen III synthase UROS 7390 NM_000375 /// XM_005270137 /// XM_005270138 /// XM_005270139 /// XM_005270140 /// XM_005270141 /// XM_006717960 /// XR_246103 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006780 // uroporphyrinogen III biosynthetic process // inferred from direct assay /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // inferred from direct assay /// 0006783 // heme biosynthetic process // traceable author statement /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0071243 // cellular response to arsenic-containing substance // inferred from electronic annotation /// 0071418 // cellular response to amine stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0004852 // uroporphyrinogen-III synthase activity // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 203032_s_at AI363836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI363836 /FEA=EST /DB_XREF=gi:4123525 /DB_XREF=est:qy62g01.x1 /CLONE=IMAGE:2016624 /UG=Hs.75653 fumarate hydratase /FL=gb:BC003108.1 gb:M15502.1 gb:U59309.1 gb:U48857.1 gb:NM_000143.1 AI363836 fumarate hydratase FH 2271 NM_000143 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006106 // fumarate metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0045239 // tricarboxylic acid cycle enzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004333 // fumarate hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 203033_x_at NM_000143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000143.1 /DEF=Homo sapiens fumarate hydratase (FH), mRNA. /FEA=mRNA /GEN=FH /PROD=fumarate hydratase /DB_XREF=gi:4503716 /UG=Hs.75653 fumarate hydratase /FL=gb:BC003108.1 gb:M15502.1 gb:U59309.1 gb:U48857.1 gb:NM_000143.1 NM_000143 fumarate hydratase FH 2271 NM_000143 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006106 // fumarate metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0045239 // tricarboxylic acid cycle enzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004333 // fumarate hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 203034_s_at NM_000990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000990.1 /DEF=Homo sapiens ribosomal protein L27a (RPL27A), mRNA. /FEA=mRNA /GEN=RPL27A /PROD=ribosomal protein L27a /DB_XREF=gi:4506624 /UG=Hs.76064 ribosomal protein L27a /FL=gb:BC005326.1 gb:NM_000990.1 gb:U14968.1 NM_000990 ribosomal protein L27a /// small nucleolar RNA, H/ACA box 45A RPL27A /// SNORA45A 6157 /// 619562 NM_000990 /// NM_032650 /// NR_002580 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042371 // vitamin K biosynthetic process // inferred from direct assay /// 0042371 // vitamin K biosynthetic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004659 // prenyltransferase activity // inferred from direct assay /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203035_s_at NM_006099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006099.1 /DEF=Homo sapiens protein inhibitor of activated STAT3 (PIAS3), mRNA. /FEA=mRNA /GEN=PIAS3 /PROD=protein inhibitor of activated STAT3 /DB_XREF=gi:5174628 /UG=Hs.76578 protein inhibitor of activated STAT3 /FL=gb:BC001154.1 gb:AB021868.1 gb:NM_006099.1 NM_006099 protein inhibitor of activated STAT, 3 PIAS3 10401 NM_006099 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction 203036_s_at AI027678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI027678 /FEA=EST /DB_XREF=gi:3245117 /DB_XREF=est:ov89e02.x1 /CLONE=IMAGE:1644506 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AB007889.1 gb:NM_014751.1 AI027678 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203037_s_at NM_014751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014751.1 /DEF=Homo sapiens KIAA0429 gene product (KIAA0429), mRNA. /FEA=mRNA /GEN=KIAA0429 /PROD=KIAA0429 gene product /DB_XREF=gi:7662113 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AB007889.1 gb:NM_014751.1 NM_014751 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203038_at NM_002844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002844.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, K (PTPRK), mRNA. /FEA=mRNA /GEN=PTPRK /PROD=protein tyrosine phosphatase, receptor type, K /DB_XREF=gi:4506316 /UG=Hs.79005 protein tyrosine phosphatase, receptor type, K /FL=gb:L77886.1 gb:NM_002844.1 NM_002844 protein tyrosine phosphatase, receptor type, K PTPRK 5796 NM_001135648 /// NM_001291981 /// NM_001291982 /// NM_001291983 /// NM_001291984 /// NM_002844 /// XM_005267082 /// XM_005267085 /// XM_005267086 /// XM_006715535 /// XM_006715536 /// XM_006715537 /// XM_006715538 /// XM_006715539 /// XM_006715540 /// XM_006715541 /// XM_006725019 /// XM_006725020 /// XM_006725021 /// XM_006725022 /// XM_006725023 /// XM_006725024 /// XM_006725025 /// XM_006725026 /// XM_006725027 0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010839 // negative regulation of keratinocyte proliferation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction 203039_s_at NM_005006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005006.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase) (NDUFS1), mRNA. /FEA=mRNA /GEN=NDUFS1 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 1(75kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4826855 /UG=Hs.8248 NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase) /FL=gb:NM_005006.1 NM_005006 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) NDUFS1 4719 NM_001199981 /// NM_001199982 /// NM_001199983 /// NM_001199984 /// NM_005006 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042773 // ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from mutant phenotype /// 0046034 // ATP metabolic process // inferred from mutant phenotype /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 203040_s_at NM_000190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000190.1 /DEF=Homo sapiens hydroxymethylbilane synthase (HMBS), mRNA. /FEA=mRNA /GEN=HMBS /PROD=hydroxymethylbilane synthase /DB_XREF=gi:4504422 /UG=Hs.82609 hydroxymethylbilane synthase /FL=gb:BC000520.1 gb:NM_000190.1 NM_000190 hydroxymethylbilane synthase HMBS 3145 NM_000190 /// NM_001024382 /// NM_001258208 /// NM_001258209 /// XM_005271531 /// XM_005271532 /// XM_005271533 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // traceable author statement /// 0018160 // peptidyl-pyrromethane cofactor linkage // inferred from electronic annotation /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004418 // hydroxymethylbilane synthase activity // inferred from direct assay /// 0004418 // hydroxymethylbilane synthase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 203041_s_at J04183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04183.1 /DEF=Homo sapiens lysosomal membrane glycoprotein-2 (LAMP2), complete cds. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal membrane glycoprotein-2 /DB_XREF=gi:186929 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:J04183.1 gb:NM_002294.1 J04183 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 203042_at NM_002294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002294.1 /DEF=Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2A, mRNA. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal-associated membrane protein 2precursor /DB_XREF=gi:4504956 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:J04183.1 gb:NM_002294.1 NM_002294 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 203043_at NM_004729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004729.1 /DEF=Homo sapiens Ac-like transposable element (ALTE), mRNA. /FEA=mRNA /GEN=ALTE /PROD=Ac-like transposable element /DB_XREF=gi:4759257 /UG=Hs.9933 Ac-like transposable element /FL=gb:AB018328.1 gb:NM_004729.1 NM_004729 zinc finger, BED-type containing 1 ZBED1 9189 NM_001171135 /// NM_001171136 /// NM_004729 0008152 // metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004803 // transposase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 203044_at NM_014918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014918.1 /DEF=Homo sapiens KIAA0990 protein (KIAA0990), mRNA. /FEA=mRNA /GEN=KIAA0990 /PROD=KIAA0990 protein /DB_XREF=gi:7662433 /UG=Hs.110488 KIAA0990 protein /FL=gb:AB023207.1 gb:NM_014918.1 NM_014918 chondroitin sulfate synthase 1 CHSY1 22856 NM_014918 /// XM_006720435 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation 203045_at NM_004148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004148.1 /DEF=Homo sapiens ninjurin 1 (NINJ1), mRNA. /FEA=mRNA /GEN=NINJ1 /PROD=ninjurin 1 /DB_XREF=gi:4758809 /UG=Hs.11342 ninjurin 1 /FL=gb:BC004440.1 gb:U72661.1 gb:U91512.1 gb:NM_004148.1 NM_004148 ninjurin 1 NINJ1 4814 NM_004148 0007155 // cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203046_s_at NM_003920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003920.1 /DEF=Homo sapiens timeless (Drosophila) homolog (TIMELESS), mRNA. /FEA=mRNA /GEN=TIMELESS /PROD=timeless (Drosophila) homolog /DB_XREF=gi:4507506 /UG=Hs.118631 timeless (Drosophila) homolog /FL=gb:AF098162.1 gb:AB015597.1 gb:NM_003920.1 NM_003920 timeless circadian clock TIMELESS 8914 NM_003920 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203047_at NM_005990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005990.1 /DEF=Homo sapiens serinethreonine kinase 10 (STK10), mRNA. /FEA=mRNA /GEN=STK10 /PROD=serinethreonine kinase 10 /DB_XREF=gi:5174700 /UG=Hs.16134 serinethreonine kinase 10 /FL=gb:AB015718.1 gb:NM_005990.1 gb:AF119894.1 NM_005990 serine/threonine kinase 10 STK10 6793 NM_005990 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0071593 // lymphocyte aggregation // inferred from electronic annotation /// 2000401 // regulation of lymphocyte migration // inferred from mutant phenotype 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042801 // polo kinase kinase activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 203048_s_at BE566023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE566023 /FEA=EST /DB_XREF=gi:9809743 /DB_XREF=est:601339016F1 /CLONE=IMAGE:3681626 /UG=Hs.170098 KIAA0372 gene product /FL=gb:AB002370.1 gb:NM_014639.1 BE566023 tetratricopeptide repeat domain 37 TTC37 9652 NM_014639 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203049_s_at NM_014639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014639.1 /DEF=Homo sapiens KIAA0372 gene product (KIAA0372), mRNA. /FEA=mRNA /GEN=KIAA0372 /PROD=KIAA0372 gene product /DB_XREF=gi:7662077 /UG=Hs.170098 KIAA0372 gene product /FL=gb:AB002370.1 gb:NM_014639.1 NM_014639 tetratricopeptide repeat domain 37 TTC37 9652 NM_014639 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203050_at NM_005657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005657.1 /DEF=Homo sapiens tumor protein p53-binding protein, 1 (TP53BP1), mRNA. /FEA=mRNA /GEN=TP53BP1 /PROD=tumor protein p53-binding protein, 1 /DB_XREF=gi:5032188 /UG=Hs.170263 tumor protein p53-binding protein, 1 /FL=gb:AF078776.1 gb:NM_005657.1 NM_005657 tumor protein p53 binding protein 1 TP53BP1 7158 NM_001141979 /// NM_001141980 /// NM_005657 /// XM_005254634 /// XM_005254635 /// XM_006720666 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred by curator 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from mutant phenotype /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042162 // telomeric DNA binding // inferred from electronic annotation 203051_at NM_014952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014952.1 /DEF=Homo sapiens KIAA0945 protein (KIAA0945), mRNA. /FEA=mRNA /GEN=KIAA0945 /PROD=KIAA0945 protein /DB_XREF=gi:7662397 /UG=Hs.22109 KIAA0945 protein /FL=gb:AB023162.1 gb:NM_014952.1 NM_014952 bromo adjacent homology domain containing 1 BAHD1 22893 NM_014952 /// XM_005254229 /// XM_005254230 /// XM_005254231 /// XM_006720436 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031507 // heterochromatin assembly // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203052_at NM_000063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000063.1 /DEF=Homo sapiens complement component 2 (C2), mRNA. /FEA=mRNA /GEN=C2 /PROD=complement component 2 /DB_XREF=gi:4557382 /UG=Hs.2253 complement component 2 /FL=gb:NM_000063.1 NM_000063 complement component 2 C2 717 NM_000063 /// NM_001145903 /// NM_001178063 /// NM_001282457 /// NM_001282458 /// NM_001282459 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // inferred from mutant phenotype /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 2000427 // positive regulation of apoptotic cell clearance // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203053_at NM_005872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005872.1 /DEF=Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA. /FEA=mRNA /GEN=BCAS2 /PROD=breast carcinoma amplified sequence 2 /DB_XREF=gi:5031652 /UG=Hs.22960 breast carcinoma amplified sequence 2 /FL=gb:BC005285.1 gb:AF081788.1 gb:AB020623.1 gb:NM_005872.1 NM_005872 breast carcinoma amplified sequence 2 BCAS2 10286 NM_005872 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203054_s_at NM_022171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022171.1 /DEF=Homo sapiens T-cell leukemia translocation altered gene (TCTA), mRNA. /FEA=mRNA /GEN=TCTA /PROD=T-cell leukemia translocation altered gene /DB_XREF=gi:11560140 /UG=Hs.250894 T-cell leukemia translocation altered gene /FL=gb:NM_022171.1 gb:BC005157.1 NM_022171 T-cell leukemia translocation altered TCTA 6988 NM_022171 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203055_s_at NM_004706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004706.1 /DEF=Homo sapiens Rho guanine nucleotide exchange factor (GEF) 1 (ARHGEF1), mRNA. /FEA=mRNA /GEN=ARHGEF1 /PROD=Rho guanine nucleotide exchange factor (GEF) 1 /DB_XREF=gi:4759189 /UG=Hs.252280 Rho guanine nucleotide exchange factor (GEF) 1 /FL=gb:BC005155.1 gb:NM_004706.1 NM_004706 Rho guanine nucleotide exchange factor (GEF) 1 /// uncharacterized LOC100505585 ARHGEF1 /// LOC100505585 9138 /// 100505585 NM_004706 /// NM_198977 /// NM_199002 /// XM_005259386 /// XM_005259387 /// XM_005259388 /// XM_005259389 /// XM_005259390 /// XM_006723463 /// XR_109536 /// XR_133186 /// XR_172294 0007266 // Rho protein signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203056_s_at AI681013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI681013 /FEA=EST /DB_XREF=gi:4891195 /DB_XREF=est:tx43d04.x1 /CLONE=IMAGE:2272327 /UG=Hs.26719 zinc-finger DNA-binding protein /FL=gb:D45132.1 gb:NM_015866.1 AI681013 PR domain containing 2, with ZNF domain PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203057_s_at AV724783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV724783 /FEA=EST /DB_XREF=gi:10829513 /DB_XREF=est:AV724783 /CLONE=HTBCEG11 /UG=Hs.26719 zinc-finger DNA-binding protein /FL=gb:D45132.1 gb:NM_015866.1 AV724783 PR domain containing 2, with ZNF domain PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203058_s_at AW299958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299958 /FEA=EST /DB_XREF=gi:6709635 /DB_XREF=est:xs44g05.x1 /CLONE=IMAGE:2772536 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1 AW299958 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203059_s_at NM_004670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004670.1 /DEF=Homo sapiens 3-phosphoadenosine 5-phosphosulfate synthase 2 (PAPSS2), mRNA. /FEA=mRNA /GEN=PAPSS2 /PROD=3-prime-phosphoadenosine 5-prime-phosphosulfatesynthase 2 /DB_XREF=gi:4758879 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1 NM_004670 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203060_s_at AF074331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074331.1 /DEF=Homo sapiens PAPS synthetase-2 (PAPSS2) mRNA, complete cds. /FEA=mRNA /GEN=PAPSS2 /PROD=PAPS synthetase-2 /DB_XREF=gi:5052074 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1 AF074331 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203061_s_at AI673553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI673553 /FEA=EST /DB_XREF=gi:4853284 /DB_XREF=est:we75d11.x1 /CLONE=IMAGE:2346933 /UG=Hs.277585 KIAA0170 gene product /FL=gb:D79992.1 gb:NM_014641.1 AI673553 mediator of DNA-damage checkpoint 1 MDC1 9656 NM_014641 /// XM_005249492 /// XM_005249493 /// XM_005249494 /// XM_005249497 /// XM_005249498 /// XM_005272909 /// XM_005272910 /// XM_005272911 /// XM_005272914 /// XM_005272915 /// XM_005274899 /// XM_005274900 /// XM_005274901 /// XM_005274904 /// XM_005274905 /// XM_005275065 /// XM_005275066 /// XM_005275067 /// XM_005275070 /// XM_005275071 /// XM_005275196 /// XM_005275198 /// XM_005275199 /// XM_005275200 /// XM_005275321 /// XM_005275322 /// XM_005275323 /// XM_005275326 /// XM_005275327 /// XM_005275492 /// XM_005275493 /// XM_005275494 /// XM_005275497 /// XM_005275498 /// XM_005275629 /// XM_005275630 /// XM_005275631 /// XM_005275634 /// XM_005275635 /// XM_006725856 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0070975 // FHA domain binding // inferred from physical interaction 203062_s_at NM_014641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014641.1 /DEF=Homo sapiens KIAA0170 gene product (KIAA0170), mRNA. /FEA=mRNA /GEN=KIAA0170 /PROD=KIAA0170 gene product /DB_XREF=gi:7661965 /UG=Hs.277585 KIAA0170 gene product /FL=gb:D79992.1 gb:NM_014641.1 NM_014641 mediator of DNA-damage checkpoint 1 MDC1 9656 NM_014641 /// XM_005249492 /// XM_005249493 /// XM_005249494 /// XM_005249497 /// XM_005249498 /// XM_005272909 /// XM_005272910 /// XM_005272911 /// XM_005272914 /// XM_005272915 /// XM_005274899 /// XM_005274900 /// XM_005274901 /// XM_005274904 /// XM_005274905 /// XM_005275065 /// XM_005275066 /// XM_005275067 /// XM_005275070 /// XM_005275071 /// XM_005275196 /// XM_005275198 /// XM_005275199 /// XM_005275200 /// XM_005275321 /// XM_005275322 /// XM_005275323 /// XM_005275326 /// XM_005275327 /// XM_005275492 /// XM_005275493 /// XM_005275494 /// XM_005275497 /// XM_005275498 /// XM_005275629 /// XM_005275630 /// XM_005275631 /// XM_005275634 /// XM_005275635 /// XM_006725856 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0070975 // FHA domain binding // inferred from physical interaction 203063_at NM_014634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014634.1 /DEF=Homo sapiens KIAA0015 gene product (KIAA0015), mRNA. /FEA=mRNA /GEN=KIAA0015 /PROD=KIAA0015 gene product /DB_XREF=gi:7661861 /UG=Hs.278441 KIAA0015 gene product /FL=gb:D13640.1 gb:NM_014634.1 NM_014634 protein phosphatase, Mg2+/Mn2+ dependent, 1F PPM1F 9647 NM_014634 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010811 // positive regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045927 // positive regulation of growth // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203064_s_at NM_004514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004514.1 /DEF=Homo sapiens interleukin enhancer binding factor 1 (ILF1), mRNA. /FEA=mRNA /GEN=ILF1 /PROD=interleukin enhancer binding factor 1 /DB_XREF=gi:4758599 /UG=Hs.296281 interleukin enhancer binding factor 1 /FL=gb:U58196.1 gb:NM_004514.1 NM_004514 forkhead box K2 FOXK2 3607 NM_004514 /// NM_181430 /// NM_181431 /// XM_006722281 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203065_s_at NM_001753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001753.2 /DEF=Homo sapiens caveolin 1, caveolae protein, 22kD (CAV1), mRNA. /FEA=mRNA /GEN=CAV1 /PROD=caveolin 1 /DB_XREF=gi:4580417 /UG=Hs.323469 caveolin 1, caveolae protein, 22kD /FL=gb:NM_001753.2 NM_001753 caveolin 1, caveolae protein, 22kDa CAV1 857 NM_001172895 /// NM_001172896 /// NM_001172897 /// NM_001753 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003057 // regulation of the force of heart contraction by chemical signal // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0030301 // cholesterol transport // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030857 // negative regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0031295 // T cell costimulation // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032507 // maintenance of protein location in cell // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033484 // nitric oxide homeostasis // inferred from sequence or structural similarity /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0052547 // regulation of peptidase activity // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060056 // mammary gland involution // inferred from sequence or structural similarity /// 0070836 // caveola assembly // inferred from mutant phenotype /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0072584 // caveolin-mediated endocytosis // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0005901 // caveola // non-traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005113 // patched binding // non-traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // traceable author statement /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0032947 // protein complex scaffold // traceable author statement /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 203066_at NM_014863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014863.1 /DEF=Homo sapiens B cell RAG associated protein (BRAG), mRNA. /FEA=mRNA /GEN=BRAG /PROD=KIAA0598 gene product /DB_XREF=gi:7662195 /UG=Hs.6079 B cell RAG associated protein /FL=gb:AB011170.1 gb:AF026477.1 gb:NM_014863.1 gb:NM_015892.1 NM_014863 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 CHST15 51363 NM_001270764 /// NM_001270765 /// NM_014863 /// NM_015892 /// XM_005269891 /// XM_005269892 /// XM_005269893 /// XM_005269894 /// XM_006717891 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019319 // hexose biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // inferred from direct assay /// 0050659 // N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity // inferred from direct assay 203067_at NM_003477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003477.1 /DEF=Homo sapiens Pyruvate dehydrogenase complex, lipoyl-containing component X; E3-binding protein (PDX1), mRNA. /FEA=mRNA /GEN=PDX1 /PROD=Pyruvate dehydrogenase complex,lipoyl-containing component X /DB_XREF=gi:4505698 /UG=Hs.74642 Pyruvate dehydrogenase complex, lipoyl-containing component X; E3-binding protein /FL=gb:AF001437.1 gb:U82328.1 gb:NM_003477.1 NM_003477 pyruvate dehydrogenase complex, component X PDHX 8050 NM_001135024 /// NM_001166158 /// NM_003477 0006090 // pyruvate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 203068_at NM_014851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014851.1 /DEF=Homo sapiens KIAA0469 gene product (KIAA0469), mRNA. /FEA=mRNA /GEN=KIAA0469 /PROD=KIAA0469 gene product /DB_XREF=gi:7662139 /UG=Hs.7764 KIAA0469 gene product /FL=gb:AB007938.1 gb:NM_014851.1 NM_014851 kelch-like family member 21 KLHL21 9903 NM_014851 /// XM_005263542 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0035853 // chromosome passenger complex localization to spindle midzone // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 203069_at NM_014849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014849.1 /DEF=Homo sapiens KIAA0736 gene product (KIAA0736), mRNA. /FEA=mRNA /GEN=KIAA0736 /PROD=KIAA0736 gene product /DB_XREF=gi:7662271 /UG=Hs.7979 KIAA0736 gene product /FL=gb:AB018279.1 gb:NM_014849.1 NM_014849 synaptic vesicle glycoprotein 2A SV2A 9900 NM_001278719 /// NM_014849 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 203070_at NM_004636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004636.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (SEMA3B), mRNA. /FEA=mRNA /GEN=SEMA3B /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3B /DB_XREF=gi:4759091 /UG=Hs.82222 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B /FL=gb:NM_004636.1 gb:U28369.1 NM_004636 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B SEMA3B 7869 NM_001005914 /// NM_001290060 /// NM_001290061 /// NM_001290062 /// NM_001290063 /// NM_004636 /// NR_110697 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 203071_at NM_004636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004636.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (SEMA3B), mRNA. /FEA=mRNA /GEN=SEMA3B /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3B /DB_XREF=gi:4759091 /UG=Hs.82222 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B /FL=gb:NM_004636.1 gb:U28369.1 NM_004636 microRNA 6872 /// sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B MIR6872 /// SEMA3B 7869 /// 102465526 NM_001005914 /// NM_001290060 /// NM_001290061 /// NM_001290062 /// NM_001290063 /// NM_004636 /// NR_106932 /// NR_110697 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 203072_at NM_004998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004998.1 /DEF=Homo sapiens myosin IC (MYO1C), mRNA. /FEA=mRNA /GEN=MYO1C /PROD=myosin IC /DB_XREF=gi:4826843 /UG=Hs.82251 myosin IC /FL=gb:NM_004998.1 gb:U14391.1 NM_004998 myosin IE MYO1E 4643 NM_004998 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003094 // glomerular filtration // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030048 // actin filament-based movement // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016459 // myosin complex // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000146 // microfilament motor activity // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 203073_at NM_007357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007357.1 /DEF=Homo sapiens low density lipoprotein receptor defect C complementing (LDLC), mRNA. /FEA=mRNA /GEN=LDLC /PROD=low density lipoprotein receptor defect Ccomplementing /DB_XREF=gi:6678675 /UG=Hs.82399 low density lipoprotein receptor defect C complementing /FL=gb:NM_007357.1 NM_007357 component of oligomeric golgi complex 2 COG2 22796 NM_001145036 /// NM_007357 0006486 // protein glycosylation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0009312 // oligosaccharide biosynthetic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from mutant phenotype /// 0032403 // protein complex binding // inferred from electronic annotation 203074_at NM_001630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001630.1 /DEF=Homo sapiens annexin A8 (ANXA8), mRNA. /FEA=mRNA /GEN=ANXA8 /PROD=annexin VIII /DB_XREF=gi:4502112 /UG=Hs.87268 annexin A8 /FL=gb:BC004376.1 gb:M81844.1 gb:NM_001630.1 NM_001630 annexin A8 /// annexin A8-like 1 ANXA8 /// ANXA8L1 653145 /// 728113 NM_001039801 /// NM_001040084 /// NM_001098845 /// NM_001271702 /// NM_001271703 /// NM_001278923 /// NM_001278924 /// NM_001630 /// XM_006717951 /// XR_246202 /// XR_428714 0007032 // endosome organization // inferred from mutant phenotype /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900138 // negative regulation of phospholipase A2 activity // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 203075_at AW151617 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW151617 /FEA=EST /DB_XREF=gi:6199515 /DB_XREF=est:xf66g01.x1 /CLONE=IMAGE:2623056 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1 AW151617 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 203076_s_at U65019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U65019.1 /DEF=Human MAD-related protein 2 (MADR2) mRNA, complete cds. /FEA=mRNA /GEN=MADR2 /PROD=MAD-related protein 2 /DB_XREF=gi:1575529 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1 U65019 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 203077_s_at NM_005901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005901.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 2 (MADH2), mRNA. /FEA=mRNA /GEN=MADH2 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 2 /DB_XREF=gi:5174510 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1 NM_005901 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 203078_at U83410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U83410.1 /DEF=Human CUL-2 (cul-2) mRNA, complete cds. /FEA=mRNA /GEN=cul-2 /PROD=CUL-2 /DB_XREF=gi:1923242 /UG=Hs.82919 cullin 2 /FL=gb:U83410.1 gb:NM_003591.1 gb:AF126404.1 U83410 cullin 2 CUL2 8453 NM_001198777 /// NM_001198778 /// NM_001198779 /// NM_003591 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 203079_s_at NM_003591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003591.1 /DEF=Homo sapiens cullin 2 (CUL2), mRNA. /FEA=mRNA /GEN=CUL2 /PROD=cullin 2 /DB_XREF=gi:4503162 /UG=Hs.82919 cullin 2 /FL=gb:U83410.1 gb:NM_003591.1 gb:AF126404.1 NM_003591 cullin 2 CUL2 8453 NM_001198777 /// NM_001198778 /// NM_001198779 /// NM_003591 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 203080_s_at NM_013450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013450.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 2B (BAZ2B), mRNA. /FEA=mRNA /GEN=BAZ2B /PROD=bromodomain adjacent to zinc finger domain, 2B /DB_XREF=gi:7304922 /UG=Hs.8383 bromodomain adjacent to zinc finger domain, 2B /FL=gb:AB032255.1 gb:NM_013450.1 NM_013450 bromodomain adjacent to zinc finger domain, 2B BAZ2B 29994 NM_001289975 /// NM_013450 /// NR_110586 /// XM_005246488 /// XM_005246489 /// XM_005246492 /// XM_005246497 /// XM_005246500 /// XM_006712461 /// XM_006712462 /// XM_006712463 /// XM_006712464 /// XM_006712465 /// XM_006712466 /// XM_006712467 /// XM_006712468 /// XM_006712469 /// XM_006712470 /// XM_006712471 /// XM_006712472 /// XM_006712473 /// XM_006712474 /// XR_425476 /// XR_427178 /// XR_431488 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203081_at NM_020248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020248.1 /DEF=Homo sapiens beta-catenin-interacting protein ICAT (LOC56998), mRNA. /FEA=mRNA /GEN=LOC56998 /PROD=beta-catenin-interacting protein ICAT /DB_XREF=gi:9910389 /UG=Hs.99816 beta-catenin-interacting protein ICAT /FL=gb:AB021262.1 gb:NM_020248.1 NM_020248 catenin, beta interacting protein 1 CTNNBIP1 56998 NM_001012329 /// NM_020248 /// XM_006710779 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0002528 // regulation of vascular permeability involved in acute inflammatory response // inferred from mutant phenotype /// 0009952 // anterior/posterior pattern specification // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // not recorded /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045657 // positive regulation of monocyte differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0060633 // negative regulation of transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0072201 // negative regulation of mesenchymal cell proliferation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 203082_at NM_014753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014753.1 /DEF=Homo sapiens KIAA0187 gene product (KIAA0187), mRNA. /FEA=mRNA /GEN=KIAA0187 /PROD=KIAA0187 gene product /DB_XREF=gi:7661979 /UG=Hs.10848 KIAA0187 gene product /FL=gb:D80009.1 gb:NM_014753.1 NM_014753 BMS1 ribosome biogenesis factor BMS1 9790 NM_014753 /// XM_005271846 /// XM_005271847 /// XM_005271848 /// XM_005271849 /// XM_006718081 /// XR_246522 /// XR_428728 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203083_at NM_003247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003247.1 /DEF=Homo sapiens thrombospondin 2 (THBS2), mRNA. /FEA=mRNA /GEN=THBS2 /PROD=thrombospondin 2 /DB_XREF=gi:4507486 /UG=Hs.108623 thrombospondin 2 /FL=gb:L12350.1 gb:NM_003247.1 NM_003247 thrombospondin 2 THBS2 7058 NM_003247 0007155 // cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation 203084_at NM_000660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000660.1 /DEF=Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA. /FEA=mRNA /GEN=TGFB1 /PROD=transforming growth factor, beta 1 /DB_XREF=gi:10863872 /UG=Hs.1103 transforming growth factor, beta 1 /FL=gb:NM_000660.1 gb:BC000125.1 gb:BC001180.1 gb:M38449.1 NM_000660 transforming growth factor, beta 1 TGFB1 7040 NM_000660 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // traceable author statement /// 0002460 // adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009817 // defense response to fungus, incompatible interaction // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0019058 // viral life cycle // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030334 // regulation of cell migration // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from expression pattern /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031536 // positive regulation of exit from mitosis // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0032943 // mononuclear cell proliferation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042306 // regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043932 // ossification involved in bone remodeling // inferred from expression pattern /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0051101 // regulation of DNA binding // inferred from sequence or structural similarity /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060312 // regulation of blood vessel remodeling // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060751 // branch elongation involved in mammary gland duct branching // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061035 // regulation of cartilage development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1901203 // positive regulation of extracellular matrix assembly // inferred by curator /// 1901666 // positive regulation of NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 2000628 // regulation of miRNA metabolic process // inferred from direct assay /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203085_s_at BC000125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000125.1 /DEF=Homo sapiens, Similar to transforming growth factor, beta 1, clone MGC:3119, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transforming growth factor, beta 1 /DB_XREF=gi:12652748 /UG=Hs.1103 transforming growth factor, beta 1 /FL=gb:NM_000660.1 gb:BC000125.1 gb:BC001180.1 gb:M38449.1 BC000125 transforming growth factor, beta 1 TGFB1 7040 NM_000660 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // traceable author statement /// 0002460 // adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009817 // defense response to fungus, incompatible interaction // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0019058 // viral life cycle // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030334 // regulation of cell migration // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from expression pattern /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031536 // positive regulation of exit from mitosis // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0032943 // mononuclear cell proliferation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042306 // regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043932 // ossification involved in bone remodeling // inferred from expression pattern /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0051101 // regulation of DNA binding // inferred from sequence or structural similarity /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060312 // regulation of blood vessel remodeling // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060751 // branch elongation involved in mammary gland duct branching // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061035 // regulation of cartilage development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1901203 // positive regulation of extracellular matrix assembly // inferred by curator /// 1901666 // positive regulation of NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 2000628 // regulation of miRNA metabolic process // inferred from direct assay /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203086_at BE872563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE872563 /FEA=EST /DB_XREF=gi:10321339 /DB_XREF=est:601451167F1 /CLONE=IMAGE:3854969 /UG=Hs.113319 kinesin heavy chain member 2 /FL=gb:NM_004520.1 BE872563 kinesin heavy chain member 2A KIF2A 3796 NM_001098511 /// NM_001243952 /// NM_001243953 /// NM_004520 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203087_s_at NM_004520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004520.1 /DEF=Homo sapiens kinesin heavy chain member 2 (KIF2), mRNA. /FEA=mRNA /GEN=KIF2 /PROD=kinesin heavy chain member 2 /DB_XREF=gi:4758643 /UG=Hs.113319 kinesin heavy chain member 2 /FL=gb:NM_004520.1 NM_004520 kinesin heavy chain member 2A KIF2A 3796 NM_001098511 /// NM_001243952 /// NM_001243953 /// NM_004520 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203088_at NM_006329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006329.1 /DEF=Homo sapiens fibulin 5 (FBLN5), mRNA. /FEA=mRNA /GEN=FBLN5 /PROD=fibulin 5 /DB_XREF=gi:5453649 /UG=Hs.11494 fibulin 5 /FL=gb:AF093118.1 gb:AF112152.1 gb:NM_006329.1 NM_006329 fibulin 5 FBLN5 10516 NM_006329 /// XM_005267267 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from sequence or structural similarity /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071953 // elastic fiber // inferred from sequence or structural similarity 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 203089_s_at NM_013247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013247.1 /DEF=Homo sapiens HtrA-like serine protease (OMI), mRNA. /FEA=mRNA /GEN=OMI /PROD=HtrA-like serine protease /DB_XREF=gi:7019476 /UG=Hs.115721 HtrA-like serine protease /FL=gb:BC000096.1 gb:AF020760.2 gb:NM_013247.1 gb:AF141305.1 NM_013247 HtrA serine peptidase 2 HTRA2 27429 NM_013247 /// NM_145074 /// XM_005264266 0006508 // proteolysis // inferred from mutant phenotype /// 0006508 // proteolysis // traceable author statement /// 0006672 // ceramide metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0009635 // response to herbicide // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016540 // protein autoprocessing // traceable author statement /// 0019742 // pentacyclic triterpenoid metabolic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001269 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005739 // mitochondrion // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 203090_at NM_006923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006923.1 /DEF=Homo sapiens stromal cell-derived factor 2 (SDF2), mRNA. /FEA=mRNA /GEN=SDF2 /PROD=stromal cell-derived factor 2 /DB_XREF=gi:5902073 /UG=Hs.118684 stromal cell-derived factor 2 /FL=gb:BC000500.1 gb:BC001406.1 gb:D50645.1 gb:NM_006923.1 NM_006923 stromal cell-derived factor 2 SDF2 6388 NM_006923 /// NR_045585 0006486 // protein glycosylation // traceable author statement /// 0035269 // protein O-linked mannosylation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // traceable author statement 203091_at NM_003902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003902.1 /DEF=Homo sapiens far upstream element (FUSE) binding protein 1 (FUBP1), mRNA. /FEA=mRNA /GEN=FUBP1 /PROD=far upstream element-binding protein /DB_XREF=gi:4503800 /UG=Hs.118962 far upstream element (FUSE) binding protein 1 /FL=gb:NM_003902.1 gb:U05040.1 NM_003902 far upstream element (FUSE) binding protein 1 FUBP1 8880 NM_003902 /// XM_005271309 /// XM_006711021 /// XM_006711022 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203092_at AF026030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026030.1 /DEF=Homo sapiens putative mitochondrial inner membrane protein import receptor (hTIM44) mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /GEN=hTIM44 /PROD=putative mitochondrial inner membrane proteinimport receptor /DB_XREF=gi:4103601 /UG=Hs.123178 translocase of inner mitochondrial membrane 44 (yeast) homolog /FL=gb:AF026030.1 gb:NM_006351.1 AF026030 translocase of inner mitochondrial membrane 44 homolog (yeast) TIMM44 10469 NM_006351 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203093_s_at NM_006351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006351.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 44 (yeast) homolog (TIM44), mRNA. /FEA=mRNA /GEN=TIM44 /PROD=translocase of inner mitochondrial membrane 44(yeast) homolog /DB_XREF=gi:5454123 /UG=Hs.123178 translocase of inner mitochondrial membrane 44 (yeast) homolog /FL=gb:AF026030.1 gb:NM_006351.1 NM_006351 translocase of inner mitochondrial membrane 44 homolog (yeast) TIMM44 10469 NM_006351 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203094_at NM_014628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014628.1 /DEF=Homo sapiens gene predicted from cDNA with a complete coding sequence (KIAA0110), mRNA. /FEA=mRNA /GEN=KIAA0110 /PROD=gene predicted from cDNA with a complete codingsequence /DB_XREF=gi:7661917 /UG=Hs.124 gene predicted from cDNA with a complete coding sequence /FL=gb:BC002904.1 gb:D14811.1 gb:NM_014628.1 NM_014628 MAD2L1 binding protein MAD2L1BP 9587 NM_001003690 /// NM_014628 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007096 // regulation of exit from mitosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203095_at NM_002453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002453.1 /DEF=Homo sapiens mitochondrial translational initiation factor 2 (MTIF2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTIF2 /PROD=mitochondrial translational initiation factor 2precursor /DB_XREF=gi:4505276 /UG=Hs.149894 mitochondrial translational initiation factor 2 /FL=gb:NM_002453.1 gb:L34600.1 NM_002453 mitochondrial translational initiation factor 2 MTIF2 4528 NM_001005369 /// NM_002453 /// XM_005264335 /// XM_006712023 /// XM_006712024 0001732 // formation of translation initiation complex // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from sequence or structural similarity /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032790 // ribosome disassembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from sequence or structural similarity /// 0043024 // ribosomal small subunit binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 203096_s_at BF439282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439282 /FEA=EST /DB_XREF=gi:11451799 /DB_XREF=est:nab62c11.x1 /CLONE=IMAGE:3272444 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 /FL=gb:AB002311.1 gb:NM_014247.1 BF439282 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 203097_s_at NM_014247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014247.1 /DEF=Homo sapiens PDZ domain containing guanine nucleotide exchange factor(GEF)1 (PDZ-GEF1), mRNA. /FEA=mRNA /GEN=PDZ-GEF1 /PROD=PDZ domain containing guanine nucleotideexchange factor(GEF)1 /DB_XREF=gi:7657260 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 /FL=gb:AB002311.1 gb:NM_014247.1 NM_014247 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 203098_at AL050164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050164.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C1622 (from clone DKFZp586C1622); partial cds. /FEA=mRNA /GEN=DKFZp586C1622 /PROD=hypothetical protein /DB_XREF=gi:4884378 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1 AL050164 chromodomain protein, Y-like CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 203099_s_at AF081258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081258.1 /DEF=Homo sapiens testis-specific chromodomain Y-like protein (CDYL) mRNA, alternatively processed, complete cds. /FEA=mRNA /GEN=CDYL /PROD=testis-specific chromodomain Y-like protein /DB_XREF=gi:4558755 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1 AF081258 chromodomain protein, Y-like CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 203100_s_at NM_004824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004824.1 /DEF=Homo sapiens chromodomain protein, Y chromosome-like (CDYL), mRNA. /FEA=mRNA /GEN=CDYL /PROD=chromodomain protein, Y chromosome-like /DB_XREF=gi:4757969 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1 NM_004824 chromodomain protein, Y-like CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 203101_s_at AW103265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW103265 /FEA=EST /DB_XREF=gi:6073916 /DB_XREF=est:xd67b03.x1 /CLONE=IMAGE:2602637 /UG=Hs.172195 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:NM_002408.2 AW103265 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase MGAT2 4247 NM_001015883 /// NM_002408 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008455 // alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 203102_s_at NM_002408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002408.2 /DEF=Homo sapiens mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2), mRNA. /FEA=mRNA /GEN=MGAT2 /PROD=alpha-1,6-mannosyl-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:6031183 /UG=Hs.172195 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:NM_002408.2 NM_002408 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase MGAT2 4247 NM_001015883 /// NM_002408 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008455 // alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 203103_s_at NM_014502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014502.1 /DEF=Homo sapiens nuclear matrix protein NMP200 related to splicing factor PRP19 (NMP200), mRNA. /FEA=mRNA /GEN=NMP200 /PROD=nuclear matrix protein NMP200 related tosplicing factor PRP19 /DB_XREF=gi:7657380 /UG=Hs.173980 nuclear matrix protein NMP200 related to splicing factor PRP19 /FL=gb:NM_014502.1 NM_014502 pre-mRNA processing factor 19 PRPF19 27339 NM_014502 0000209 // protein polyubiquitination // inferred from direct assay /// 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 203104_at NM_005211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005211.1 /DEF=Homo sapiens colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R), mRNA. /FEA=mRNA /GEN=CSF1R /PROD=colony stimulating factor 1 receptor, formerlyMcDonough feline sarcoma viral (v-fms) oncogene homolog /DB_XREF=gi:4885158 /UG=Hs.174142 colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog /FL=gb:NM_005211.1 NM_005211 colony stimulating factor 1 receptor CSF1R 1436 NM_001288705 /// NM_005211 /// NR_109969 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030224 // monocyte differentiation // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from mutant phenotype /// 0038145 // macrophage colony-stimulating factor signaling pathway // inferred from electronic annotation /// 0038145 // macrophage colony-stimulating factor signaling pathway // inferred from mutant phenotype /// 0038145 // macrophage colony-stimulating factor signaling pathway // traceable author statement /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045217 // cell-cell junction maintenance // inferred from mutant phenotype /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity /// 0060603 // mammary gland duct morphogenesis // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0090197 // positive regulation of chemokine secretion // inferred from mutant phenotype /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005011 // macrophage colony-stimulating factor receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from direct assay /// 0019955 // cytokine binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 203105_s_at NM_012062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012062.1 /DEF=Homo sapiens dynamin 1-like (DNM1L), transcript variant 1, mRNA. /FEA=mRNA /GEN=DNM1L /PROD=dynamin 1-like protein, isoform 1 /DB_XREF=gi:6996004 /UG=Hs.180628 dynamin 1-like /FL=gb:AF000430.1 gb:AB006965.1 gb:NM_012062.1 NM_012062 dynamin 1-like DNM1L 10059 NM_001278463 /// NM_001278464 /// NM_001278465 /// NM_001278466 /// NM_005690 /// NM_012062 /// NM_012063 /// XM_005253282 /// XM_005253283 0000266 // mitochondrial fission // inferred from direct assay /// 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0003374 // dynamin polymerization involved in mitochondrial fission // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0010821 // regulation of mitochondrion organization // inferred from mutant phenotype /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0032459 // regulation of protein oligomerization // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0061025 // membrane fusion // inferred from direct assay /// 0070266 // necroptotic process // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // traceable author statement /// 0090149 // membrane fission involved in mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 1900063 // regulation of peroxisome organization // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 203106_s_at NM_014396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014396.1 /DEF=Homo sapiens vacuolar protein sorting 41 (yeast homolog) (VPS41), mRNA. /FEA=mRNA /GEN=VPS41 /PROD=vacuolar protein sorting 41 (yeast homolog) /DB_XREF=gi:7657676 /UG=Hs.180941 vacuolar protein sorting 41 (yeast homolog) /FL=gb:U87309.1 gb:NM_014396.1 NM_014396 vacuolar protein sorting 41 homolog (S. cerevisiae) VPS41 27072 NM_014396 /// NM_080631 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030897 // HOPS complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203107_x_at NM_002952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002952.1 /DEF=Homo sapiens ribosomal protein S2 (RPS2), mRNA. /FEA=mRNA /GEN=RPS2 /PROD=ribosomal protein S2 /DB_XREF=gi:4506718 /UG=Hs.182426 ribosomal protein S2 /FL=gb:BC001795.1 gb:NM_002952.1 NM_002952 ribosomal protein S2 /// small nucleolar RNA, H/ACA box 64 RPS2 /// SNORA64 6187 /// 26784 NM_002952 /// NR_002326 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051347 // positive regulation of transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203108_at NM_003979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003979.2 /DEF=Homo sapiens retinoic acid induced 3 (RAI3), mRNA. /FEA=mRNA /GEN=RAI3 /PROD=retinoic acid induced 3 /DB_XREF=gi:12056470 /UG=Hs.194691 retinoic acid induced 3 /FL=gb:NM_003979.2 gb:BC003665.1 gb:AF095448.1 NM_003979 G protein-coupled receptor, class C, group 5, member A GPRC5A 9052 NM_003979 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 203109_at NM_003969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003969.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12) (UBE2M), mRNA. /FEA=mRNA /GEN=UBE2M /PROD=ubiquitin-conjugating enzyme E2M (homologous toyeast UBC12) /DB_XREF=gi:4507790 /UG=Hs.200478 ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12) /FL=gb:AF075599.1 gb:AB012191.1 gb:NM_003969.1 NM_003969 ubiquitin-conjugating enzyme E2M UBE2M 9040 NM_003969 0006464 // cellular protein modification process // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0018169 // ribosomal S6-glutamic acid ligase activity // inferred from direct assay /// 0019788 // NEDD8 ligase activity // inferred from direct assay 203110_at U43522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43522.1 /DEF=Human cell adhesion kinase beta (CAKbeta) mRNA, complete cds. /FEA=mRNA /GEN=CAKbeta /PROD=cell adhesion kinase beta /DB_XREF=gi:1165218 /UG=Hs.20313 protein tyrosine kinase 2 beta /FL=gb:L49207.1 gb:U43522.1 gb:NM_004103.1 gb:U33284.1 U43522 protein tyrosine kinase 2 beta PTK2B 2185 NM_004103 /// NM_173174 /// NM_173175 /// NM_173176 /// XM_005273447 /// XM_005273448 0000165 // MAPK cascade // inferred from electronic annotation /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002315 // marginal zone B cell differentiation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from mutant phenotype /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0010752 // regulation of cGMP-mediated signaling // inferred from electronic annotation /// 0010758 // regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0030826 // regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0032960 // regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042976 // activation of Janus kinase activity // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045428 // regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050848 // regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 2000058 // regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043423 // 3-phosphoinositide-dependent protein kinase binding // inferred from electronic annotation 203111_s_at NM_004103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004103.1 /DEF=Homo sapiens protein tyrosine kinase 2 beta (PTK2B), mRNA. /FEA=mRNA /GEN=PTK2B /PROD=protein tyrosine kinase 2 beta /DB_XREF=gi:4758975 /UG=Hs.20313 protein tyrosine kinase 2 beta /FL=gb:L49207.1 gb:U43522.1 gb:NM_004103.1 gb:U33284.1 NM_004103 protein tyrosine kinase 2 beta PTK2B 2185 NM_004103 /// NM_173174 /// NM_173175 /// NM_173176 /// XM_005273447 /// XM_005273448 0000165 // MAPK cascade // inferred from electronic annotation /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002315 // marginal zone B cell differentiation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from mutant phenotype /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0010752 // regulation of cGMP-mediated signaling // inferred from electronic annotation /// 0010758 // regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0030826 // regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0032960 // regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042976 // activation of Janus kinase activity // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045428 // regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050848 // regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 2000058 // regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043423 // 3-phosphoinositide-dependent protein kinase binding // inferred from electronic annotation 203112_s_at NM_005663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005663.1 /DEF=Homo sapiens Wolf-Hirschhorn syndrome candidate 2 (WHSC2), mRNA. /FEA=mRNA /GEN=WHSC2 /PROD=WHSC2 protein /DB_XREF=gi:5032226 /UG=Hs.21771 Wolf-Hirschhorn syndrome candidate 2 /FL=gb:BC002764.1 gb:AF101434.1 gb:NM_005663.1 NM_005663 microRNA 943 /// negative elongation factor complex member A MIR943 /// NELFA 7469 /// 100126332 NM_005663 /// NR_030641 /// XM_006713916 /// XM_006713917 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203113_s_at NM_001960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001960.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), mRNA. /FEA=mRNA /GEN=EEF1D /PROD=eukaryotic translation elongation factor 1 delta(guanine nucleotide exchange protein) /DB_XREF=gi:4503478 /UG=Hs.223241 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) /FL=gb:NM_001960.1 NM_001960 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) EEF1D 1936 NM_001130053 /// NM_001130054 /// NM_001130055 /// NM_001130056 /// NM_001130057 /// NM_001195203 /// NM_001289950 /// NM_001960 /// NM_032378 /// XM_005250820 /// XM_005250821 /// XM_005250823 /// XM_005250824 /// XM_005250825 /// XM_005250826 /// XM_006716519 /// XM_006716520 /// XM_006716521 /// XM_006716522 /// XM_006716523 /// XM_006716524 /// XM_006716525 /// XM_006725064 /// XM_006725065 /// XM_006725066 /// XM_006725067 /// XM_006725068 /// XM_006725069 /// XM_006725070 /// XM_006725071 /// XM_006725072 /// XM_006725073 /// XM_006725074 /// XM_006725075 /// XM_006725076 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 203114_at NM_006396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006396.1 /DEF=Homo sapiens Sjogrens syndromescleroderma autoantigen 1 (SSSCA1), mRNA. /FEA=mRNA /GEN=SSSCA1 /PROD=Sjogrens syndromescleroderma autoantigen 1 /DB_XREF=gi:5453837 /UG=Hs.25723 Sjogrens syndromescleroderma autoantigen 1 /FL=gb:AB001740.1 gb:NM_006396.1 NM_006396 Sjogren syndrome/scleroderma autoantigen 1 SSSCA1 10534 NM_006396 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203115_at AU152635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152635 /FEA=EST /DB_XREF=gi:11014156 /DB_XREF=est:AU152635 /CLONE=NT2RP3001344 /UG=Hs.26 ferrochelatase (protoporphyria) /FL=gb:NM_000140.1 AU152635 ferrochelatase FECH 2235 NM_000140 /// NM_001012515 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009416 // response to light stimulus // traceable author statement /// 0009589 // detection of UV // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046501 // protoporphyrinogen IX metabolic process // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070541 // response to platinum ion // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004325 // ferrochelatase activity // inferred from direct assay /// 0004325 // ferrochelatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030350 // iron-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046906 // tetrapyrrole binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 203116_s_at NM_000140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000140.1 /DEF=Homo sapiens ferrochelatase (protoporphyria) (FECH), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FECH /PROD=ferrochelatase precursor /DB_XREF=gi:4557592 /UG=Hs.26 ferrochelatase (protoporphyria) /FL=gb:NM_000140.1 NM_000140 ferrochelatase FECH 2235 NM_000140 /// NM_001012515 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009416 // response to light stimulus // traceable author statement /// 0009589 // detection of UV // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046501 // protoporphyrinogen IX metabolic process // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070541 // response to platinum ion // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004325 // ferrochelatase activity // inferred from direct assay /// 0004325 // ferrochelatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030350 // iron-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046906 // tetrapyrrole binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 203117_s_at NM_014871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014871.1 /DEF=Homo sapiens KIAA0710 gene product (KIAA0710), mRNA. /FEA=mRNA /GEN=KIAA0710 /PROD=KIAA0710 gene product /DB_XREF=gi:7662257 /UG=Hs.273397 KIAA0710 gene product /FL=gb:AB014610.1 gb:NM_014871.1 NM_014871 PAN2 poly(A) specific ribonuclease subunit PAN2 9924 NM_001127460 /// NM_001166279 /// NM_014871 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031251 // PAN complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203118_at NM_004716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004716.1 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 7 (PCSK7), mRNA. /FEA=mRNA /GEN=PCSK7 /PROD=proprotein convertase subtilisinkexin type 7 /DB_XREF=gi:4758887 /UG=Hs.32978 proprotein convertase subtilisinkexin type 7 /FL=gb:U40623.1 gb:U33849.1 gb:NM_004716.1 NM_004716 proprotein convertase subtilisin/kexin type 7 PCSK7 9159 NM_004716 /// XM_006718938 /// XM_006718939 /// XM_006718940 /// XR_428984 /// XR_428985 0006508 // proteolysis // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // non-traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203119_at NM_024098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024098.1 /DEF=Homo sapiens hypothetical protein MGC2574 (MGC2574), mRNA. /FEA=mRNA /GEN=MGC2574 /PROD=hypothetical protein MGC2574 /DB_XREF=gi:13129103 /UG=Hs.4253 hypothetical protein MGC2574 /FL=gb:BC001378.1 gb:NM_024098.1 NM_024098 coiled-coil domain containing 86 CCDC86 79080 NM_024098 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203120_at NM_005426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005426.1 /DEF=Homo sapiens tumor protein p53-binding protein, 2 (TP53BP2), mRNA. /FEA=mRNA /GEN=TP53BP2 /PROD=tumor protein p53-binding protein, 2 /DB_XREF=gi:4885642 /UG=Hs.44585 tumor protein p53-binding protein, 2 /FL=gb:U58334.1 gb:NM_005426.1 NM_005426 tumor protein p53 binding protein 2 TP53BP2 7159 NM_001031685 /// NM_005426 /// XM_005273246 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 203122_at NM_016030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016030.1 /DEF=Homo sapiens CGI-87 protein (LOC51112), mRNA. /FEA=mRNA /GEN=LOC51112 /PROD=CGI-87 protein /DB_XREF=gi:7705796 /UG=Hs.5008 CGI-87 protein /FL=gb:AF151845.1 gb:NM_016030.1 NM_016030 trafficking protein particle complex 12 TRAPPC12 51112 NM_016030 /// XM_005264693 /// XM_006711887 /// XR_426956 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203123_s_at AU154469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154469 /FEA=EST /DB_XREF=gi:11015990 /DB_XREF=est:AU154469 /CLONE=NT2RP4001182 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1 AU154469 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203124_s_at NM_000617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000617.1 /DEF=Homo sapiens solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), mRNA. /FEA=mRNA /GEN=SLC11A2 /PROD=solute carrier family 11 (proton-coupleddivalent metal ion transporters), member 2 /DB_XREF=gi:10835168 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1 NM_000617 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203125_x_at AF046997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF046997.1 /DEF=Homo sapiens NRAMP2 iron transporter mRNA, complete cds. /FEA=mRNA /PROD=NRAMP2 iron transporter /DB_XREF=gi:3170363 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1 AF046997 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203126_at NM_014214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014214.1 /DEF=Homo sapiens inositol(myo)-1(or 4)-monophosphatase 2 (IMPA2), mRNA. /FEA=mRNA /GEN=IMPA2 /PROD=inositol(myo)-1(or 4)-monophosphatase 2 /DB_XREF=gi:7657235 /UG=Hs.5753 inositol(myo)-1(or 4)-monophosphatase 2 /FL=gb:AF200432.1 gb:NM_014214.1 gb:AF014398.2 NM_014214 inositol(myo)-1(or 4)-monophosphatase 2 IMPA2 3613 NM_014214 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0008934 // inositol monophosphate 1-phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation 203127_s_at BC005123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005123.1 /DEF=Homo sapiens, serine palmitoyltransferase, long chain base subunit 2, clone MGC:10362, mRNA, complete cds. /FEA=mRNA /PROD=serine palmitoyltransferase, long chain basesubunit 2 /DB_XREF=gi:13477298 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 /FL=gb:BC005123.1 gb:AB011098.1 gb:NM_004863.1 BC005123 serine palmitoyltransferase, long chain base subunit 2 SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 203128_at NM_004863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004863.1 /DEF=Homo sapiens serine palmitoyltransferase, long chain base subunit 2 (SPTLC2), mRNA. /FEA=mRNA /GEN=SPTLC2 /PROD=serine palmitoyltransferase, long chain basesubunit 2 /DB_XREF=gi:4758667 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 /FL=gb:BC005123.1 gb:AB011098.1 gb:NM_004863.1 NM_004863 serine palmitoyltransferase, long chain base subunit 2 SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 203129_s_at BF059313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF059313 /FEA=EST /DB_XREF=gi:10813297 /DB_XREF=est:7k60c04.x1 /CLONE=IMAGE:3479791 /UG=Hs.6641 kinesin family member 5C /FL=gb:AB011103.1 gb:NM_004522.1 BF059313 kinesin family member 5C KIF5C 3800 NM_004522 /// NR_111932 0006810 // transport // inferred from electronic annotation /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203130_s_at NM_004522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004522.1 /DEF=Homo sapiens kinesin family member 5C (KIF5C), mRNA. /FEA=mRNA /GEN=KIF5C /PROD=kinesin family member 5C /DB_XREF=gi:4758649 /UG=Hs.6641 kinesin family member 5C /FL=gb:AB011103.1 gb:NM_004522.1 NM_004522 kinesin family member 5C KIF5C 3800 NM_004522 /// NR_111932 0006810 // transport // inferred from electronic annotation /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203131_at NM_006206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006206.1 /DEF=Homo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), mRNA. /FEA=mRNA /GEN=PDGFRA /PROD=platelet-derived growth factor receptor, alphapolypeptide /DB_XREF=gi:5453869 /UG=Hs.74615 platelet-derived growth factor receptor, alpha polypeptide /FL=gb:M21574.1 gb:NM_006206.1 NM_006206 platelet-derived growth factor receptor, alpha polypeptide PDGFRA 5156 NM_006206 /// XM_005265743 /// XM_006714039 /// XM_006714040 /// XM_006714041 0001553 // luteinization // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030539 // male genitalia development // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035790 // platelet-derived growth factor receptor-alpha signaling pathway // inferred from mutant phenotype /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2000739 // regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from mutant phenotype /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 203132_at NM_000321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000321.1 /DEF=Homo sapiens retinoblastoma 1 (including osteosarcoma) (RB1), mRNA. /FEA=mRNA /GEN=RB1 /PROD=retinoblastoma 1 (including osteosarcoma) /DB_XREF=gi:4506434 /UG=Hs.75770 retinoblastoma 1 (including osteosarcoma) /FL=gb:M33647.1 gb:M15400.1 gb:M28419.1 gb:NM_000321.1 NM_000321 retinoblastoma 1 RB1 5925 NM_000321 0000075 // cell cycle checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from physical interaction /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031134 // sister chromatid biorientation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from mutant phenotype /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071459 // protein localization to chromosome, centromeric region // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0090230 // regulation of centromere complex assembly // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016514 // SWI/SNF complex // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0035189 // Rb-E2F complex // traceable author statement 0001047 // core promoter binding // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0051219 // phosphoprotein binding // inferred from physical interaction 203133_at NM_006808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006808.1 /DEF=Homo sapiens protein translocation complex beta (SEC61B), mRNA. /FEA=mRNA /GEN=SEC61B /PROD=protein translocation complex beta /DB_XREF=gi:5803164 /UG=Hs.77028 protein translocation complex beta /FL=gb:BC001734.1 gb:L25085.1 gb:NM_006808.1 NM_006808 Sec61 beta subunit SEC61B 10952 NM_006808 0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0031205 // endoplasmic reticulum Sec complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from physical interaction 203134_at NM_007166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007166.1 /DEF=Homo sapiens Clathrin assembly lymphoid-myeloid leukemia gene (CLTH), mRNA. /FEA=mRNA /GEN=CLTH /PROD=Clathrin assembly lymphoid-myeloid leukemiagene /DB_XREF=gi:6005732 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein /FL=gb:U45976.1 gb:NM_007166.1 NM_007166 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 203135_at NM_003194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003194.1 /DEF=Homo sapiens TATA box binding protein (TBP), mRNA. /FEA=mRNA /GEN=TBP /PROD=TATA box binding protein /DB_XREF=gi:4507378 /UG=Hs.1100 TATA box binding protein /FL=gb:M34960.1 gb:M55654.1 gb:NM_003194.1 NM_003194 TATA box binding protein TBP 6908 NM_001172085 /// NM_003194 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005672 // transcription factor TFIIA complex // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from physical interaction 203136_at NM_006423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006423.1 /DEF=Homo sapiens Rab acceptor 1 (prenylated) (RABAC1), mRNA. /FEA=mRNA /GEN=RABAC1 /PROD=Rab acceptor 1 (prenylated) /DB_XREF=gi:5453959 /UG=Hs.11417 Rab acceptor 1 (prenylated) /FL=gb:NM_006423.1 gb:AF112202.1 NM_006423 Rab acceptor 1 (prenylated) RABAC1 10567 NM_006423 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from electronic annotation 203137_at NM_004906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004906.1 /DEF=Homo sapiens Wilms tumour 1-associating protein (KIAA0105), mRNA. /FEA=mRNA /GEN=KIAA0105 /PROD=Wilms tumour 1-associating protein /DB_XREF=gi:4758635 /UG=Hs.119 Wilms tumour 1-associating protein /FL=gb:AF277190.1 gb:D14661.1 gb:NM_004906.1 NM_004906 Wilms tumor 1 associated protein WTAP 9589 NM_001270531 /// NM_001270532 /// NM_001270533 /// NM_004906 /// NM_152857 /// NM_152858 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0080009 // mRNA methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 203138_at NM_003642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003642.1 /DEF=Homo sapiens histone acetyltransferase 1 (HAT1), mRNA. /FEA=mRNA /GEN=HAT1 /PROD=histone acetyltransferase 1 /DB_XREF=gi:4504340 /UG=Hs.13340 histone acetyltransferase 1 /FL=gb:AF030424.1 gb:NM_003642.1 NM_003642 histone acetyltransferase 1 HAT1 8520 NM_001033085 /// NM_003642 /// NR_027862 /// XM_006712808 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006348 // chromatin silencing at telomere // inferred from electronic annotation /// 0006475 // internal protein amino acid acetylation // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 203139_at NM_004938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004938.1 /DEF=Homo sapiens death-associated protein kinase 1 (DAPK1), mRNA. /FEA=mRNA /GEN=DAPK1 /PROD=death-associated protein kinase 1 /DB_XREF=gi:4826683 /UG=Hs.153924 death-associated protein kinase 1 /FL=gb:NM_004938.1 NM_004938 death-associated protein kinase 1 DAPK1 1612 NM_001288729 /// NM_001288730 /// NM_001288731 /// NM_004938 /// XM_005251757 /// XM_006716988 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203140_at NM_001706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001706.1 /DEF=Homo sapiens B-cell CLLlymphoma 6 (zinc finger protein 51) (BCL6), mRNA. /FEA=mRNA /GEN=BCL6 /PROD=B-cell CLLlymphoma 6 (zinc finger protein 51) /DB_XREF=gi:4502382 /UG=Hs.155024 B-cell CLLlymphoma 6 (zinc finger protein 51) /FL=gb:U00115.1 gb:NM_001706.1 NM_001706 B-cell CLL/lymphoma 6 BCL6 604 NM_001130845 /// NM_001134738 /// NM_001706 /// NM_138931 /// XM_005247694 0000060 // protein import into nucleus, translocation // inferred from genetic interaction /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // non-traceable author statement /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032764 // negative regulation of mast cell cytokine production // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042092 // type 2 immune response // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043380 // regulation of memory T cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0048294 // negative regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203141_s_at AW058575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW058575 /FEA=EST /DB_XREF=gi:5934214 /DB_XREF=est:wx23f04.x1 /CLONE=IMAGE:2544511 /UG=Hs.155172 adaptor-related protein complex 3, beta 1 subunit /FL=gb:U91931.1 gb:U81504.1 gb:NM_003664.1 AW058575 adaptor-related protein complex 3, beta 1 subunit AP3B1 8546 NM_001271769 /// NM_003664 /// XM_005248618 /// XM_005248619 0006622 // protein targeting to lysosome // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203142_s_at NM_003664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003664.1 /DEF=Homo sapiens adaptor-related protein complex 3, beta 1 subunit (AP3B1), mRNA. /FEA=mRNA /GEN=AP3B1 /PROD=adaptor-related protein complex 3, beta 1subunit /DB_XREF=gi:4501974 /UG=Hs.155172 adaptor-related protein complex 3, beta 1 subunit /FL=gb:U91931.1 gb:U81504.1 gb:NM_003664.1 NM_003664 adaptor-related protein complex 3, beta 1 subunit AP3B1 8546 NM_001271769 /// NM_003664 /// XM_005248618 /// XM_005248619 0006622 // protein targeting to lysosome // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203143_s_at T79953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T79953 /FEA=EST /DB_XREF=gi:698462 /DB_XREF=est:yd85c11.s1 /CLONE=IMAGE:115028 /UG=Hs.158282 KIAA0040 gene product /FL=gb:D25539.1 gb:NM_014656.1 T79953 KIAA0040 KIAA0040 9674 NM_001162893 /// NM_001162894 /// NM_001162895 /// NM_014656 /// XM_005245628 203144_s_at NM_014656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014656.1 /DEF=Homo sapiens KIAA0040 gene product (KIAA0040), mRNA. /FEA=mRNA /GEN=KIAA0040 /PROD=KIAA0040 gene product /DB_XREF=gi:7657258 /UG=Hs.158282 KIAA0040 gene product /FL=gb:D25539.1 gb:NM_014656.1 NM_014656 KIAA0040 KIAA0040 9674 NM_001162893 /// NM_001162894 /// NM_001162895 /// NM_014656 /// XM_005245628 203145_at NM_006461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006461.1 /DEF=Homo sapiens mitotic spindle coiled-coil related protein (DEEPEST), mRNA. /FEA=mRNA /GEN=DEEPEST /PROD=mitotic spindle coiled-coil related protein /DB_XREF=gi:5453631 /UG=Hs.16244 mitotic spindle coiled-coil related protein /FL=gb:BC000322.1 gb:AF063308.1 gb:NM_006461.1 NM_006461 sperm associated antigen 5 SPAG5 10615 NM_006461 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007051 // spindle organization // non-traceable author statement /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203146_s_at NM_001470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001470.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=GABBR1 /PROD=gamma-aminobutyric acid (GABA) B receptor 1,isoform a precursor /DB_XREF=gi:10835014 /UG=Hs.167017 gamma-aminobutyric acid (GABA) B receptor, 1 /FL=gb:NM_001470.1 gb:AF301005.1 gb:AF099148.1 NM_001470 gamma-aminobutyric acid (GABA) B receptor, 1 GABBR1 2550 NM_001470 /// NM_021903 /// NM_021904 /// NM_021905 /// XM_005248982 /// XM_005272785 /// XM_005274841 /// XM_005274931 /// XM_005275088 /// XM_005275227 /// XM_005275363 /// XM_006715047 /// XM_006725030 /// XM_006725477 /// XM_006725691 /// XM_006725807 /// XM_006725901 /// XM_006725988 /// XR_241884 /// XR_246960 /// XR_247352 /// XR_247386 /// XR_247400 /// XR_430672 /// XR_430972 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032446 // protein modification by small protein conjugation // non-traceable author statement /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from expression pattern /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0043011 // myeloid dendritic cell differentiation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 203147_s_at BE962483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962483 /FEA=EST /DB_XREF=gi:11765431 /DB_XREF=est:601655782R1 /CLONE=IMAGE:3846116 /UG=Hs.179703 KIAA0129 gene product /FL=gb:D50919.1 gb:NM_014788.1 BE962483 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203148_s_at NM_014788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014788.1 /DEF=Homo sapiens KIAA0129 gene product (KIAA0129), mRNA. /FEA=mRNA /GEN=KIAA0129 /PROD=KIAA0129 gene product /DB_XREF=gi:7661927 /UG=Hs.179703 KIAA0129 gene product /FL=gb:D50919.1 gb:NM_014788.1 NM_014788 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203149_at NM_002856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002856.1 /DEF=Homo sapiens poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), mRNA. /FEA=mRNA /GEN=PVRL2 /PROD=poliovirus receptor-related 2 (herpesvirus entrymediator B) /DB_XREF=gi:5360209 /UG=Hs.183986 poliovirus receptor-related 2 (herpesvirus entry mediator B) /FL=gb:BC003091.1 gb:AF058448.1 gb:NM_002856.1 NM_002856 poliovirus receptor-related 2 (herpesvirus entry mediator B) PVRL2 5819 NM_001042724 /// NM_002856 0001675 // acrosome assembly // inferred from electronic annotation /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0002891 // positive regulation of immunoglobulin mediated immune response // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0030382 // sperm mitochondrion organization // inferred from electronic annotation /// 0032990 // cell part morphogenesis // inferred from electronic annotation /// 0033005 // positive regulation of mast cell activation // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0044782 // cilium organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0046814 // coreceptor-mediated virion attachment to host cell // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051654 // establishment of mitochondrion localization // inferred from electronic annotation /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 203150_at NM_005833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005833.1 /DEF=Homo sapiens Rab9 effector p40 (RAB9P40), mRNA. /FEA=mRNA /GEN=RAB9P40 /PROD=Rab9 effector p40 /DB_XREF=gi:5032014 /UG=Hs.19012 Rab9 effector p40 /FL=gb:BC000503.1 gb:Z97074.1 gb:NM_005833.1 NM_005833 Rab9 effector protein with kelch motifs RABEPK 10244 NM_001174152 /// NM_001174153 /// NM_005833 /// XM_005251640 /// XM_005251641 /// XM_005251642 /// XM_005251643 /// XM_005251644 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203151_at AW296788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW296788 /FEA=EST /DB_XREF=gi:6703424 /DB_XREF=est:UI-H-BW0-ajb-d-08-0-UI.s1 /CLONE=IMAGE:2731071 /UG=Hs.194301 microtubule-associated protein 1A /FL=gb:U38292.1 gb:NM_002373.1 gb:U14577.1 AW296788 microtubule-associated protein 1A MAP1A 4130 NM_002373 /// XM_005254385 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203152_at NM_003776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003776.1 /DEF=Homo sapiens nuclear localization signal deleted in velocardiofacial syndrome (NLVCF), mRNA. /FEA=mRNA /GEN=NLVCF /PROD=nuclear localization signal deleted invelocardiofacial syndrome protein /DB_XREF=gi:4505402 /UG=Hs.19500 nuclear localization signal deleted in velocardiofacial syndrome /FL=gb:AF034091.1 gb:NM_003776.1 NM_003776 mitochondrial ribosomal protein L40 MRPL40 64976 NM_003776 /// XM_005261267 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 203153_at NM_001548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001548.1 /DEF=Homo sapiens interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), mRNA. /FEA=mRNA /GEN=IFIT1 /PROD=interferon-induced protein withtetratricopeptide repeats 1 /DB_XREF=gi:4504584 /UG=Hs.20315 interferon-induced protein with tetratricopeptide repeats 1 /FL=gb:M24594.1 gb:NM_001548.1 NM_001548 interferon-induced protein with tetratricopeptide repeats 1 IFIT1 3434 NM_001270927 /// NM_001270928 /// NM_001270929 /// NM_001270930 /// NM_001548 0002376 // immune system process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay /// 0051097 // negative regulation of helicase activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071357 // cellular response to type I interferon // inferred from direct assay /// 0071360 // cellular response to exogenous dsRNA // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203154_s_at NM_005884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005884.2 /DEF=Homo sapiens protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs (PAK4), mRNA. /FEA=mRNA /GEN=PAK4 /PROD=protein kinase related to S. cerevisiae STE20,effector for Cdc42Hs /DB_XREF=gi:7382497 /UG=Hs.20447 protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs /FL=gb:AF005046.1 gb:NM_005884.2 NM_005884 p21 protein (Cdc42/Rac)-activated kinase 4 PAK4 10298 NM_001014831 /// NM_001014832 /// NM_001014833 /// NM_001014834 /// NM_001014835 /// NM_005884 /// XM_006722971 /// XM_006722972 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203155_at NM_012432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012432.1 /DEF=Homo sapiens SET domain, bifurcated 1 (SETDB1), mRNA. /FEA=mRNA /GEN=SETDB1 /PROD=SET domain, bifurcated 1 /DB_XREF=gi:6912651 /UG=Hs.20991 SET domain, bifurcated 1 /FL=gb:D31891.1 gb:NM_012432.1 NM_012432 SET domain, bifurcated 1 SETDB1 9869 NM_001145415 /// NM_001243491 /// NM_012432 /// XM_005245641 /// XM_006711672 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203156_at NM_016248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016248.1 /DEF=Homo sapiens A-kinase anchoring protein 220 (LOC51707), mRNA. /FEA=mRNA /GEN=LOC51707 /PROD=A-kinase anchoring protein 220 /DB_XREF=gi:7706456 /UG=Hs.232076 A kinase (PRKA) anchor protein 11 /FL=gb:AF176555.1 gb:NM_016248.1 NM_016248 A kinase (PRKA) anchor protein 11 AKAP11 11215 NM_016248 /// NM_144490 /// XM_005266247 /// XM_005266248 /// XM_005266249 /// XM_005266250 0035556 // intracellular signal transduction // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0008157 // protein phosphatase 1 binding // traceable author statement /// 0051018 // protein kinase A binding // traceable author statement 203157_s_at AB020645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020645.1 /DEF=Homo sapiens mRNA for KIAA0838 protein, complete cds. /FEA=mRNA /GEN=KIAA0838 /PROD=KIAA0838 protein /DB_XREF=gi:4240164 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1 AB020645 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203158_s_at AF097493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF097493.1 /DEF=Homo sapiens glutaminase kidney isoform mRNA, complete cds. /FEA=mRNA /PROD=glutaminase kidney isoform /DB_XREF=gi:6002672 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1 AF097493 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203159_at NM_014905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014905.1 /DEF=Homo sapiens glutaminase (GLS), mRNA. /FEA=mRNA /GEN=GLS /PROD=glutaminase C /DB_XREF=gi:7662327 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1 NM_014905 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203160_s_at AK022075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022075.1 /DEF=Homo sapiens cDNA FLJ12013 fis, clone HEMBB1001673, highly similar to Homo sapiens gene for new zinc finger protein. /FEA=mRNA /DB_XREF=gi:10433395 /UG=Hs.24439 ring finger protein (C3HC4 type) 8 /FL=gb:AB014546.1 gb:NM_003958.1 AK022075 ring finger protein 8, E3 ubiquitin protein ligase RNF8 9025 NM_003958 /// NM_183078 /// NR_046399 /// XM_006715241 /// XM_006715242 /// XM_006715243 /// XR_427852 /// XR_427853 /// XR_427854 /// XR_427855 /// XR_427856 /// XR_427857 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from sequence or structural similarity /// 0036297 // interstrand cross-link repair // traceable author statement /// 0043486 // histone exchange // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045900 // negative regulation of translational elongation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203161_s_at NM_003958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003958.1 /DEF=Homo sapiens ring finger protein (C3HC4 type) 8 (RNF8), mRNA. /FEA=mRNA /GEN=RNF8 /PROD=ring finger protein (C3HC4 type) 8 /DB_XREF=gi:4504866 /UG=Hs.24439 ring finger protein (C3HC4 type) 8 /FL=gb:AB014546.1 gb:NM_003958.1 NM_003958 ring finger protein 8, E3 ubiquitin protein ligase RNF8 9025 NM_003958 /// NM_183078 /// NR_046399 /// XM_006715241 /// XM_006715242 /// XM_006715243 /// XR_427852 /// XR_427853 /// XR_427854 /// XR_427855 /// XR_427856 /// XR_427857 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from sequence or structural similarity /// 0036297 // interstrand cross-link repair // traceable author statement /// 0043486 // histone exchange // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045900 // negative regulation of translational elongation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203162_s_at NM_005886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005886.1 /DEF=Homo sapiens katanin p80 (WD40-containing) subunit B 1 (KATNB1), mRNA. /FEA=mRNA /GEN=KATNB1 /PROD=katanin p80 subunit B 1 /DB_XREF=gi:5031816 /UG=Hs.275675 katanin p80 (WD40-containing) subunit B 1 /FL=gb:BC001353.1 gb:AF052432.1 gb:NM_005886.1 NM_005886 katanin p80 (WD repeat containing) subunit B 1 KATNB1 10300 NM_005886 /// XM_005255772 /// XM_006721121 /// XM_006721122 /// XM_006721123 0006200 // ATP catabolic process // inferred from direct assay /// 0006605 // protein targeting // non-traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from mutant phenotype /// 0051013 // microtubule severing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0008352 // katanin complex // inferred from direct assay /// 0008352 // katanin complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0045502 // dynein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203163_at NM_005886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005886.1 /DEF=Homo sapiens katanin p80 (WD40-containing) subunit B 1 (KATNB1), mRNA. /FEA=mRNA /GEN=KATNB1 /PROD=katanin p80 subunit B 1 /DB_XREF=gi:5031816 /UG=Hs.275675 katanin p80 (WD40-containing) subunit B 1 /FL=gb:BC001353.1 gb:AF052432.1 gb:NM_005886.1 NM_005886 katanin p80 (WD repeat containing) subunit B 1 KATNB1 10300 NM_005886 /// XM_005255772 /// XM_006721121 /// XM_006721122 /// XM_006721123 0006200 // ATP catabolic process // inferred from direct assay /// 0006605 // protein targeting // non-traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from mutant phenotype /// 0051013 // microtubule severing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0008352 // katanin complex // inferred from direct assay /// 0008352 // katanin complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0045502 // dynein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203164_at BE464756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE464756 /FEA=EST /DB_XREF=gi:9510618 /DB_XREF=est:hv89d09.x1 /CLONE=IMAGE:3180593 /UG=Hs.285176 acetyl-Coenzyme A transporter /FL=gb:D88152.1 gb:NM_004733.2 BE464756 solute carrier family 33 (acetyl-CoA transporter), member 1 SLC33A1 9197 NM_001190992 /// NM_004733 /// XM_006713822 0006810 // transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008521 // acetyl-CoA transporter activity // inferred from electronic annotation 203165_s_at NM_004733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004733.2 /DEF=Homo sapiens acetyl-Coenzyme A transporter (ACATN), mRNA. /FEA=mRNA /GEN=ACATN /PROD=acetyl-Coenzyme A transporter /DB_XREF=gi:6042194 /UG=Hs.285176 acetyl-Coenzyme A transporter /FL=gb:D88152.1 gb:NM_004733.2 NM_004733 solute carrier family 33 (acetyl-CoA transporter), member 1 SLC33A1 9197 NM_001190992 /// NM_004733 /// XM_006713822 0006810 // transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008521 // acetyl-CoA transporter activity // inferred from electronic annotation 203166_at NM_006324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006324.1 /DEF=Homo sapiens craniofacial development protein 1 (CFDP1), mRNA. /FEA=mRNA /GEN=CFDP1 /PROD=craniofacial development protein 1 /DB_XREF=gi:5453566 /UG=Hs.296460 craniofacial development protein 1 /FL=gb:BC000991.2 gb:AB009285.1 gb:NM_006324.1 NM_006324 craniofacial development protein 1 CFDP1 10428 NM_006324 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 203167_at NM_003255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003255.2 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 2 (TIMP2), mRNA. /FEA=mRNA /GEN=TIMP2 /PROD=tissue inhibitor of metalloproteinase 2precursor /DB_XREF=gi:9257247 /UG=Hs.325495 tissue inhibitor of metalloproteinase 2 /FL=gb:M32304.1 gb:J05593.1 gb:NM_003255.2 NM_003255 TIMP metallopeptidase inhibitor 2 TIMP2 7077 NM_003255 0007417 // central nervous system development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030814 // regulation of cAMP metabolic process // inferred from electronic annotation /// 0032487 // regulation of Rap protein signal transduction // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045762 // positive regulation of adenylate cyclase activity // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203168_at NM_004381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004381.1 /DEF=Homo sapiens cAMP responsive element binding protein-like 1 (CREBL1), mRNA. /FEA=mRNA /GEN=CREBL1 /PROD=cAMP responsive element binding protein-like 1 /DB_XREF=gi:4758057 /UG=Hs.42853 cAMP responsive element binding protein-like 1 /FL=gb:U31903.1 gb:NM_004381.1 NM_004381 activating transcription factor 6 beta ATF6B 1388 NM_001136153 /// NM_004381 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203169_at NM_014785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014785.1 /DEF=Homo sapiens KIAA0258 gene product (KIAA0258), mRNA. /FEA=mRNA /GEN=KIAA0258 /PROD=KIAA0258 gene product /DB_XREF=gi:7662029 /UG=Hs.47313 KIAA0258 gene product /FL=gb:BC001725.1 gb:D87447.1 gb:NM_014785.1 NM_014785 RGP1 retrograde golgi transport homolog (S. cerevisiae) RGP1 9827 NM_001080496 /// XM_006716895 203170_at AB007869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007869.1 /DEF=Homo sapiens KIAA0409 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0409 /DB_XREF=gi:2662098 /UG=Hs.5158 KIAA0409 protein /FL=gb:BC001071.1 gb:NM_015324.1 AB007869 ribosomal RNA processing 8, methyltransferase, homolog (yeast) RRP8 23378 NM_015324 0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0046015 // regulation of transcription by glucose // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0033553 // rDNA heterochromatin // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203171_s_at NM_015324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015324.1 /DEF=Homo sapiens KIAA0409 protein (KIAA0409), mRNA. /FEA=mRNA /GEN=KIAA0409 /PROD=KIAA0409 protein /DB_XREF=gi:12758124 /UG=Hs.5158 KIAA0409 protein /FL=gb:BC001071.1 gb:NM_015324.1 NM_015324 ribosomal RNA processing 8, methyltransferase, homolog (yeast) RRP8 23378 NM_015324 0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0046015 // regulation of transcription by glucose // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0033553 // rDNA heterochromatin // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203172_at NM_004860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004860.2 /DEF=Homo sapiens fragile X mental retardation, autosomal homolog 2 (FXR2), mRNA. /FEA=mRNA /GEN=FXR2 /PROD=fragile X mental retardation syndrome relatedprotein 2 /DB_XREF=gi:6598321 /UG=Hs.52788 fragile X mental retardation, autosomal homolog 2 /FL=gb:U31501.1 gb:NM_004860.2 NM_004860 fragile X mental retardation, autosomal homolog 2 FXR2 9513 NM_004860 /// XR_243572 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203173_s_at AW080196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW080196 /FEA=EST /DB_XREF=gi:6035348 /DB_XREF=est:xe49g08.x1 /CLONE=IMAGE:2611262 /UG=Hs.5320 hypothetical protein /FL=gb:NM_020314.1 gb:AL136744.1 AW080196 chromosome 16 open reading frame 62 C16orf62 57020 NM_020314 /// XM_005255435 /// XM_005255436 /// XM_006721065 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203174_s_at NM_003224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003224.1 /DEF=Homo sapiens ADP-ribosylation factor related protein 1 (ARFRP1), mRNA. /FEA=mRNA /GEN=ARFRP1 /PROD=ADP-ribosylation factor related protein 1 /DB_XREF=gi:4507448 /UG=Hs.64904 ADP-ribosylation factor related protein 1 /FL=gb:NM_003224.1 NM_003224 ADP-ribosylation factor related protein 1 ARFRP1 10139 NM_001134758 /// NM_001267544 /// NM_001267545 /// NM_001267546 /// NM_001267547 /// NM_001267548 /// NM_001267549 /// NM_003224 /// NR_051954 /// NR_051955 /// NR_051956 /// NR_051957 /// NR_051958 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203175_at NM_001665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001665.1 /DEF=Homo sapiens ras homolog gene family, member G (rho G) (ARHG), mRNA. /FEA=mRNA /GEN=ARHG /PROD=ras homolog gene family, member G (rho G) /DB_XREF=gi:4502218 /UG=Hs.75082 ras homolog gene family, member G (rho G) /FL=gb:NM_001665.1 NM_001665 ras homolog family member G RHOG 391 NM_001665 /// XM_005252916 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203176_s_at BE552470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE552470 /FEA=EST /DB_XREF=gi:9794162 /DB_XREF=est:hw27d09.x1 /CLONE=IMAGE:3184145 /UG=Hs.75133 transcription factor 6-like 1 (mitochondrial transcription factor 1-like) /FL=gb:M62810.1 gb:NM_003201.1 BE552470 transcription factor A, mitochondrial TFAM 7019 NM_001270782 /// NM_003201 /// NM_012251 /// NR_073073 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033108 // mitochondrial respiratory chain complex assembly // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay 203177_x_at NM_003201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003201.1 /DEF=Homo sapiens transcription factor 6-like 1 (mitochondrial transcription factor 1-like) (TCF6L1), mRNA. /FEA=mRNA /GEN=TCF6L1 /PROD=transcription factor 6-like 1 (mitochondrialtranscription factor 1-like) /DB_XREF=gi:4507400 /UG=Hs.75133 transcription factor 6-like 1 (mitochondrial transcription factor 1-like) /FL=gb:M62810.1 gb:NM_003201.1 NM_003201 transcription factor A, mitochondrial TFAM 7019 NM_001270782 /// NM_003201 /// NM_012251 /// NR_073073 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033108 // mitochondrial respiratory chain complex assembly // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay 203178_at NM_001482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001482.1 /DEF=Homo sapiens glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM), mRNA. /FEA=mRNA /GEN=GATM /PROD=glycine amidinotransferase (L-arginine:glycineamidinotransferase) /DB_XREF=gi:4503932 /UG=Hs.75335 glycine amidinotransferase (L-arginine:glycine amidinotransferase) /FL=gb:BC004141.1 gb:NM_001482.1 NM_001482 glycine amidinotransferase (L-arginine:glycine amidinotransferase) GATM 2628 NM_001482 /// XR_424635 /// XR_429525 /// XR_433091 0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015067 // amidinotransferase activity // inferred from electronic annotation /// 0015068 // glycine amidinotransferase activity // inferred from direct assay /// 0015068 // glycine amidinotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation 203179_at NM_000155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000155.1 /DEF=Homo sapiens galactose-1-phosphate uridylyltransferase (GALT), mRNA. /FEA=mRNA /GEN=GALT /PROD=galactose-1-phosphate uridylyltransferase /DB_XREF=gi:4557614 /UG=Hs.75641 galactose-1-phosphate uridylyltransferase /FL=gb:M60091.1 gb:NM_000155.1 NM_000155 galactose-1-phosphate uridylyltransferase GALT 2592 NM_000155 /// NM_001258332 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // traceable author statement /// 0006258 // UDP-glucose catabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019388 // galactose catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0008108 // UDP-glucose:hexose-1-phosphate uridylyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046316 // gluconokinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203180_at NM_000693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000693.1 /DEF=Homo sapiens aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), mRNA. /FEA=mRNA /GEN=ALDH1A3 /PROD=aldehyde dehydrogenase 1A3 /DB_XREF=gi:4502040 /UG=Hs.75746 aldehyde dehydrogenase 1 family, member A3 /FL=gb:NM_000693.1 gb:U07919.1 NM_000693 aldehyde dehydrogenase 1 family, member A3 ALDH1A3 220 NM_000693 /// NM_001037224 /// NM_001293815 /// XR_109231 /// XR_111558 /// XR_172102 /// XR_243247 /// XR_248182 /// XR_253467 0002072 // optic cup morphogenesis involved in camera-type eye development // inferred from electronic annotation /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021768 // nucleus accumbens development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 203181_x_at AW149364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149364 /FEA=EST /DB_XREF=gi:6197260 /DB_XREF=est:xf36c05.x1 /CLONE=IMAGE:2620136 /UG=Hs.78353 SFRS protein kinase 2 /FL=gb:U88666.1 gb:NM_003138.1 AW149364 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity 203182_s_at NM_003138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003138.1 /DEF=Homo sapiens SFRS protein kinase 2 (SRPK2), mRNA. /FEA=mRNA /GEN=SRPK2 /PROD=SFRS protein kinase 2 /DB_XREF=gi:4507220 /UG=Hs.78353 SFRS protein kinase 2 /FL=gb:U88666.1 gb:NM_003138.1 NM_003138 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity 203183_s_at NM_003076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003076.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), mRNA. /FEA=mRNA /GEN=SMARCD1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily d, member 1 /DB_XREF=gi:4507082 /UG=Hs.79335 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 /FL=gb:U66617.1 gb:NM_003076.1 NM_003076 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 SMARCD1 6602 NM_003076 /// NM_139071 /// XM_005269107 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 203184_at NM_001999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001999.2 /DEF=Homo sapiens fibrillin 2 (congenital contractural arachnodactyly) (FBN2), mRNA. /FEA=mRNA /GEN=FBN2 /PROD=fibrillin 2 /DB_XREF=gi:4755135 /UG=Hs.79432 fibrillin 2 (congenital contractural arachnodactyly) /FL=gb:U03272.1 gb:NM_001999.2 NM_001999 fibrillin 2 FBN2 2201 NM_001999 0009653 // anatomical structure morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0060346 // bone trabecula formation // inferred from sequence or structural similarity 0001527 // microfibril // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203185_at NM_014737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014737.1 /DEF=Homo sapiens Ras association (RalGDSAF-6) domain family 2 (RASSF2), mRNA. /FEA=mRNA /GEN=RASSF2 /PROD=Ras association (RalGDSAF-6) domain family 2 /DB_XREF=gi:7661963 /UG=Hs.80905 Ras association (RalGDSAF-6) domain family 2 /FL=gb:D79990.1 gb:NM_014737.1 NM_014737 Ras association (RalGDS/AF-6) domain family member 2 RASSF2 9770 NM_014737 /// NM_170774 /// XM_005260895 /// XM_006723668 /// XM_006723669 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203186_s_at NM_002961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002961.2 /DEF=Homo sapiens S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) (S100A4), transcript variant 1, mRNA. /FEA=mRNA /GEN=S100A4 /PROD=S100 calcium-binding protein A4 /DB_XREF=gi:9845514 /UG=Hs.81256 S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) /FL=gb:NM_002961.2 gb:NM_019554.1 NM_002961 S100 calcium binding protein A4 S100A4 6275 NM_002961 /// NM_019554 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 203187_at NM_001380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001380.1 /DEF=Homo sapiens dedicator of cyto-kinesis 1 (DOCK1), mRNA. /FEA=mRNA /GEN=DOCK1 /PROD=dedicator of cyto-kinesis 1 /DB_XREF=gi:4503354 /UG=Hs.82295 dedicator of cyto-kinesis 1 /FL=gb:D50857.1 gb:NM_001380.1 NM_001380 dedicator of cytokinesis 1 DOCK1 1793 NM_001290223 /// NM_001380 /// XM_006717681 /// XM_006717682 /// XM_006717683 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 203188_at NM_006876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006876.1 /DEF=Homo sapiens i-beta-1,3-N-acetylglucosaminyltransferase (BETA3GNTI), mRNA. /FEA=mRNA /GEN=BETA3GNTI /PROD=i-beta-1,3-N-acetylglucosaminyltransferase /DB_XREF=gi:5802983 /UG=Hs.8526 i-beta-1,3-N-acetylglucosaminyltransferase /FL=gb:AF029893.1 gb:NM_006876.1 NM_006876 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 B3GNT1 11041 NM_006876 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030311 // poly-N-acetyllactosamine biosynthetic process // inferred from direct assay /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008532 // N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 203189_s_at NM_002496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002496.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) (NDUFS8), mRNA. /FEA=mRNA /GEN=NDUFS8 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 8(23kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4505370 /UG=Hs.90443 NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) /FL=gb:U65579.1 gb:NM_002496.1 NM_002496 microRNA 4691 /// microRNA 7113 /// NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) MIR4691 /// MIR7113 /// NDUFS8 4728 /// 100616403 /// 102465669 NM_002496 /// NR_039840 /// NR_106963 /// XM_005274013 /// XM_005274014 /// XM_005274015 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 203190_at NM_002496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002496.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) (NDUFS8), mRNA. /FEA=mRNA /GEN=NDUFS8 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 8(23kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4505370 /UG=Hs.90443 NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) /FL=gb:U65579.1 gb:NM_002496.1 NM_002496 microRNA 4691 /// microRNA 7113 /// NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) MIR4691 /// MIR7113 /// NDUFS8 4728 /// 100616403 /// 102465669 NM_002496 /// NR_039840 /// NR_106963 /// XM_005274013 /// XM_005274014 /// XM_005274015 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 203191_at AF308472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF308472.1 /DEF=Homo sapiens ATP-binding cassette half-transporter (PRP) mRNA, complete cds. /FEA=mRNA /GEN=PRP /PROD=ATP-binding cassette half-transporter /DB_XREF=gi:11245443 /UG=Hs.107911 ATP-binding cassette, sub-family B (MDRTAP), member 6 /FL=gb:AF308472.1 gb:BC000559.1 gb:AF076775.1 gb:NM_005689.1 AF308472 ATP-binding cassette, sub-family B (MDR/TAP), member 6 ABCB6 10058 NM_005689 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 203192_at NM_005689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005689.1 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 6 (ABCB6), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ABCB6 /PROD=ATP-binding cassette, sub-family B, member 6 /DB_XREF=gi:9955962 /UG=Hs.107911 ATP-binding cassette, sub-family B (MDRTAP), member 6 /FL=gb:AF308472.1 gb:BC000559.1 gb:AF076775.1 gb:NM_005689.1 NM_005689 ATP-binding cassette, sub-family B (MDR/TAP), member 6 ABCB6 10058 NM_005689 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000422 // mitochondrion degradation // not recorded /// 0000422 // mitochondrion degradation // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from electronic annotation /// 0034497 // protein localization to pre-autophagosomal structure // not recorded /// 0034497 // protein localization to pre-autophagosomal structure // /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0034727 // piecemeal microautophagy of nucleus // /// 0043588 // skin development // inferred from mutant phenotype /// 0044805 // late nucleophagy // not recorded /// 0044805 // late nucleophagy // /// 0045087 // innate immune response // inferred from electronic annotation /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0070574 // cadmium ion transmembrane transport // /// 0071585 // detoxification of cadmium ion // 0000407 // pre-autophagosomal structure // not recorded /// 0000407 // pre-autophagosomal structure // /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // /// 0005776 // autophagic vacuole // not recorded /// 0005776 // autophagic vacuole // /// 0005776 // autophagic vacuole // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0016021 // integral component of membrane // /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 203193_at NM_004451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004451.1 /DEF=Homo sapiens estrogen-related receptor alpha (ESRRA), mRNA. /FEA=mRNA /GEN=ESRRA /PROD=estrogen-related receptor alpha /DB_XREF=gi:4758305 /UG=Hs.110849 estrogen-related receptor alpha /FL=gb:NM_004451.1 NM_004451 estrogen-related receptor alpha ESRRA 2101 NM_001282450 /// NM_001282451 /// NM_004451 /// XM_006718449 /// XM_006718450 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203194_s_at AA527238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527238 /FEA=EST /DB_XREF=gi:2269307 /DB_XREF=est:ng35e10.s1 /CLONE=IMAGE:936810 /UG=Hs.112255 nucleoporin 98kD /FL=gb:NM_005387.2 gb:AF071076.1 AA527238 nucleoporin 98kDa NUP98 4928 NM_005387 /// NM_016320 /// NM_139131 /// NM_139132 /// XM_005252950 /// XM_006718240 /// XM_006718241 /// XM_006718242 /// XR_428845 0000059 // protein import into nucleus, docking // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006999 // nuclear pore organization // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0017056 // structural constituent of nuclear pore // non-traceable author statement /// 0042277 // peptide binding // inferred from electronic annotation 203195_s_at NM_005387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005387.2 /DEF=Homo sapiens nucleoporin 98kD (NUP98), mRNA. /FEA=mRNA /GEN=NUP98 /PROD=nucleoporin 98kD /DB_XREF=gi:11120677 /UG=Hs.112255 nucleoporin 98kD /FL=gb:NM_005387.2 gb:AF071076.1 NM_005387 nucleoporin 98kDa NUP98 4928 NM_005387 /// NM_016320 /// NM_139131 /// NM_139132 /// XM_005252950 /// XM_006718240 /// XM_006718241 /// XM_006718242 /// XR_428845 0000059 // protein import into nucleus, docking // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006999 // nuclear pore organization // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0017056 // structural constituent of nuclear pore // non-traceable author statement /// 0042277 // peptide binding // inferred from electronic annotation 203196_at AI948503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI948503 /FEA=EST /DB_XREF=gi:5740813 /DB_XREF=est:wq06f10.x1 /CLONE=IMAGE:2470507 /UG=Hs.139336 ATP-binding cassette, sub-family C (CFTRMRP), member 4 /FL=gb:AF071202.1 gb:NM_005845.1 AI948503 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 ABCC4 10257 NM_001105515 /// NM_005845 /// XM_005254025 /// XM_006719914 0002576 // platelet degranulation // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 203197_s_at AW157077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157077 /FEA=EST /DB_XREF=gi:6228478 /DB_XREF=est:au91f04.x1 /CLONE=IMAGE:2783647 /UG=Hs.146861 hypothetical protein FLJ20580 /FL=gb:NM_017887.1 AW157077 chromosome 1 open reading frame 123 C1orf123 54987 NM_017887 0070062 // extracellular vesicular exosome // inferred from direct assay 203198_at NM_001261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001261.1 /DEF=Homo sapiens cyclin-dependent kinase 9 (CDC2-related kinase) (CDK9), mRNA. /FEA=mRNA /GEN=CDK9 /PROD=cyclin-dependent kinase 9 (CDC2-related kinase) /DB_XREF=gi:4502746 /UG=Hs.150423 cyclin-dependent kinase 9 (CDC2-related kinase) /FL=gb:BC001968.1 gb:NM_001261.1 gb:L25676.1 NM_001261 cyclin-dependent kinase 9 CDK9 1025 NM_001261 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031056 // regulation of histone modification // inferred from direct assay /// 0043111 // replication fork arrest // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008023 // transcription elongation factor complex // traceable author statement /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017069 // snRNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 203199_s_at N29717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N29717 /FEA=EST /DB_XREF=gi:1148237 /DB_XREF=est:yw78f05.s1 /CLONE=IMAGE:258369 /UG=Hs.153792 5-methyltetrahydrofolate-homocysteine methyltransferase reductase /FL=gb:NM_024010.1 gb:AF121214.1 N29717 5-methyltetrahydrofolate-homocysteine methyltransferase reductase MTRR 4552 NM_002454 /// NM_024010 /// XM_006714474 /// XR_241702 /// XR_241703 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006555 // methionine metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0010181 // FMN binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // not recorded /// 0016723 // oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor // inferred from direct assay /// 0030586 // [methionine synthase] reductase activity // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050661 // NADP binding // traceable author statement 203200_s_at NM_024010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024010.1 /DEF=Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, mRNA. /FEA=mRNA /GEN=MTRR /PROD=methionine synthase reductase, isoform 2 /DB_XREF=gi:13325067 /UG=Hs.153792 5-methyltetrahydrofolate-homocysteine methyltransferase reductase /FL=gb:NM_024010.1 gb:AF121214.1 NM_024010 5-methyltetrahydrofolate-homocysteine methyltransferase reductase MTRR 4552 NM_002454 /// NM_024010 /// XM_006714474 /// XR_241702 /// XR_241703 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006555 // methionine metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0010181 // FMN binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // not recorded /// 0016723 // oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor // inferred from direct assay /// 0030586 // [methionine synthase] reductase activity // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050661 // NADP binding // traceable author statement 203201_at NM_000303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000303.1 /DEF=Homo sapiens phosphomannomutase 2 (PMM2), mRNA. /FEA=mRNA /GEN=PMM2 /PROD=phosphomannomutase 2 /DB_XREF=gi:4557838 /UG=Hs.154695 phosphomannomutase 2 /FL=gb:U85773.1 gb:NM_000303.1 NM_000303 phosphomannomutase 2 PMM2 5373 NM_000303 /// XM_005255372 /// XM_005255373 /// XM_005255374 0006486 // protein glycosylation // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019307 // mannose biosynthetic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004615 // phosphomannomutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 203202_at AI950314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI950314 /FEA=EST /DB_XREF=gi:5742624 /DB_XREF=est:wp08c11.x1 /CLONE=IMAGE:2464244 /UG=Hs.154762 HIV-1 rev binding protein 2 /FL=gb:U55766.1 gb:NM_007043.1 AI950314 KRR1, small subunit (SSU) processome component, homolog (yeast) KRR1 11103 NM_007043 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203203_s_at NM_007043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007043.1 /DEF=Homo sapiens HIV-1 rev binding protein 2 (HRB2), mRNA. /FEA=mRNA /GEN=HRB2 /PROD=HIV-1 rev binding protein 2 /DB_XREF=gi:5902047 /UG=Hs.154762 HIV-1 rev binding protein 2 /FL=gb:U55766.1 gb:NM_007043.1 NM_007043 KRR1, small subunit (SSU) processome component, homolog (yeast) KRR1 11103 NM_007043 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203204_s_at BC002558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002558.1 /DEF=Homo sapiens, KIAA0677 gene product, clone MGC:1972, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0677 gene product /DB_XREF=gi:12803466 /UG=Hs.155983 KIAA0677 gene product /FL=gb:BC002558.1 gb:AB014577.1 gb:NM_014663.1 BC002558 lysine (K)-specific demethylase 4A KDM4A 9682 NM_014663 /// XM_005271354 /// XM_005271355 /// XM_005271356 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay 203205_at NM_014663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014663.1 /DEF=Homo sapiens KIAA0677 gene product (KIAA0677), mRNA. /FEA=mRNA /GEN=KIAA0677 /PROD=KIAA0677 gene product /DB_XREF=gi:7662245 /UG=Hs.155983 KIAA0677 gene product /FL=gb:BC002558.1 gb:AB014577.1 gb:NM_014663.1 NM_014663 lysine (K)-specific demethylase 4A KDM4A 9682 NM_014663 /// XM_005271354 /// XM_005271355 /// XM_005271356 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay 203206_at NM_014661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014661.1 /DEF=Homo sapiens KIAA0140 gene product (KIAA0140), mRNA. /FEA=mRNA /GEN=KIAA0140 /PROD=KIAA0140 gene product /DB_XREF=gi:7661937 /UG=Hs.156016 KIAA0140 gene product /FL=gb:D50930.1 gb:NM_014661.1 NM_014661 family with sequence similarity 53, member B FAM53B 9679 NM_014661 203207_s_at BF214329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF214329 /FEA=EST /DB_XREF=gi:11107915 /DB_XREF=est:601848574F1 /CLONE=IMAGE:4079202 /UG=Hs.170198 KIAA0009 gene product /FL=gb:D13634.1 gb:NM_014637.1 BF214329 mitochondrial fission regulator 1 MTFR1 9650 NM_001145838 /// NM_001145839 /// NM_014637 /// XM_005251327 /// XM_006716484 0000266 // mitochondrial fission // inferred from sequence or structural similarity /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 203208_s_at NM_014637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014637.1 /DEF=Homo sapiens KIAA0009 gene product (KIAA0009), mRNA. /FEA=mRNA /GEN=KIAA0009 /PROD=KIAA0009 gene product /DB_XREF=gi:7661853 /UG=Hs.170198 KIAA0009 gene product /FL=gb:D13634.1 gb:NM_014637.1 NM_014637 mitochondrial fission regulator 1 MTFR1 9650 NM_001145838 /// NM_001145839 /// NM_014637 /// XM_005251327 /// XM_006716484 0000266 // mitochondrial fission // inferred from sequence or structural similarity /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 203209_at BC001866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001866.1 /DEF=Homo sapiens, replication factor C (activator 1) 5 (36.5kD), clone MGC:1155, mRNA, complete cds. /FEA=mRNA /PROD=replication factor C (activator 1) 5 (36.5kD) /DB_XREF=gi:12804840 /UG=Hs.171075 replication factor C (activator 1) 5 (36.5kD) /FL=gb:BC001866.1 gb:L07540.1 gb:NM_007370.1 BC001866 replication factor C (activator 1) 5, 36.5kDa RFC5 5985 NM_001130112 /// NM_001130113 /// NM_001206801 /// NM_007370 /// NM_181578 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 203210_s_at NM_007370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007370.1 /DEF=Homo sapiens replication factor C (activator 1) 5 (36.5kD) (RFC5), mRNA. /FEA=mRNA /GEN=RFC5 /PROD=replication factor C (activator 1) 5 (36.5kD) /DB_XREF=gi:6677722 /UG=Hs.171075 replication factor C (activator 1) 5 (36.5kD) /FL=gb:BC001866.1 gb:L07540.1 gb:NM_007370.1 NM_007370 replication factor C (activator 1) 5, 36.5kDa RFC5 5985 NM_001130112 /// NM_001130113 /// NM_001206801 /// NM_007370 /// NM_181578 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 203211_s_at AK027038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027038.1 /DEF=Homo sapiens cDNA: FLJ23385 fis, clone HEP16802. /FEA=mRNA /DB_XREF=gi:10440053 /UG=Hs.181326 KIAA1073 protein /FL=gb:AB028996.1 gb:NM_016156.1 AK027038 myotubularin related protein 2 MTMR2 8898 NM_001243571 /// NM_016156 /// NM_201278 /// NM_201281 /// XM_005274374 /// XM_005274375 /// XM_006718933 /// XM_006718934 /// XM_006718935 /// XM_006718936 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from sequence or structural similarity /// 2000645 // negative regulation of receptor catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052866 // phosphatidylinositol phosphate phosphatase activity // inferred from electronic annotation 203212_s_at NM_016156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016156.1 /DEF=Homo sapiens KIAA1073 protein (KIAA1073), mRNA. /FEA=mRNA /GEN=KIAA1073 /PROD=KIAA1073 protein /DB_XREF=gi:7705563 /UG=Hs.181326 KIAA1073 protein /FL=gb:AB028996.1 gb:NM_016156.1 NM_016156 myotubularin related protein 2 MTMR2 8898 NM_001243571 /// NM_016156 /// NM_201278 /// NM_201281 /// XM_005274374 /// XM_005274375 /// XM_006718933 /// XM_006718934 /// XM_006718935 /// XM_006718936 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from sequence or structural similarity /// 2000645 // negative regulation of receptor catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052866 // phosphatidylinositol phosphate phosphatase activity // inferred from electronic annotation 203213_at AL524035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL524035 /FEA=EST /DB_XREF=gi:12787528 /DB_XREF=est:AL524035 /CLONE=CS0DC003YN06 (3 prime) /UG=Hs.184572 cell division cycle 2, G1 to S and G2 to M /FL=gb:NM_001786.1 AL524035 cyclin-dependent kinase 1 CDK1 983 NM_001130829 /// NM_001170406 /// NM_001170407 /// NM_001786 /// NM_033379 /// XM_005270303 /// XM_006718082 /// XM_006718083 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007344 // pronuclear fusion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014038 // regulation of Schwann cell differentiation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045995 // regulation of embryonic development // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from electronic annotation 203214_x_at NM_001786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001786.1 /DEF=Homo sapiens cell division cycle 2, G1 to S and G2 to M (CDC2), mRNA. /FEA=mRNA /GEN=CDC2 /PROD=cell division cycle 2, G1 to S and G2 to M /DB_XREF=gi:4502708 /UG=Hs.184572 cell division cycle 2, G1 to S and G2 to M /FL=gb:NM_001786.1 NM_001786 cyclin-dependent kinase 1 CDK1 983 NM_001130829 /// NM_001170406 /// NM_001170407 /// NM_001786 /// NM_033379 /// XM_005270303 /// XM_006718082 /// XM_006718083 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007344 // pronuclear fusion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014038 // regulation of Schwann cell differentiation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045995 // regulation of embryonic development // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from electronic annotation 203215_s_at AA877789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA877789 /FEA=EST /DB_XREF=gi:2986754 /DB_XREF=est:nr06h10.s1 /CLONE=IMAGE:1161091 /UG=Hs.22564 myosin VI /FL=gb:AB002387.1 gb:NM_004999.1 AA877789 myosin VI MYO6 4646 NM_004999 /// XM_005248719 /// XM_005248720 /// XM_005248721 /// XM_005248722 /// XM_005248724 /// XM_005248725 /// XM_005248726 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051046 // regulation of secretion // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060001 // minus-end directed microfilament motor activity // non-traceable author statement 203216_s_at NM_004999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004999.1 /DEF=Homo sapiens myosin VI (MYO6), mRNA. /FEA=mRNA /GEN=MYO6 /PROD=myosin VI /DB_XREF=gi:4826845 /UG=Hs.22564 myosin VI /FL=gb:AB002387.1 gb:NM_004999.1 NM_004999 myosin VI MYO6 4646 NM_004999 /// XM_005248719 /// XM_005248720 /// XM_005248721 /// XM_005248722 /// XM_005248724 /// XM_005248725 /// XM_005248726 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051046 // regulation of secretion // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060001 // minus-end directed microfilament motor activity // non-traceable author statement 203217_s_at NM_003896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003896.1 /DEF=Homo sapiens sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) (SIAT9), mRNA. /FEA=mRNA /GEN=SIAT9 /PROD=sialyltransferase 9 (CMP-NeuAc:lactosylceramidealpha-2,3-sialyltransferase; GM3 synthase) /DB_XREF=gi:4506954 /UG=Hs.225939 sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) /FL=gb:AB018356.1 gb:NM_003896.1 gb:AF119415.1 NM_003896 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ST3GAL5 8869 NM_001042437 /// NM_003896 /// XM_005264630 /// XM_006712127 /// XR_244967 /// XR_426999 0001574 // ganglioside biosynthetic process // non-traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0004513 // neolactotetraosylceramide alpha-2,3-sialyltransferase activity // traceable author statement /// 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047291 // lactosylceramide alpha-2,3-sialyltransferase activity // inferred from direct assay 203218_at W37431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W37431 /FEA=EST /DB_XREF=gi:1319025 /DB_XREF=est:zc11f11.s1 /CLONE=IMAGE:322029 /UG=Hs.246857 mitogen-activated protein kinase 9 /FL=gb:U34821.1 gb:NM_002752.1 gb:L31951.1 gb:U09759.1 W37431 mitogen-activated protein kinase 9 MAPK9 5601 NM_001135044 /// NM_002752 /// NM_139068 /// NM_139069 /// NM_139070 /// XM_005265940 /// XM_006714891 0000165 // MAPK cascade // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010770 // positive regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0032308 // positive regulation of prostaglandin secretion // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004705 // JUN kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 203219_s_at NM_000485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000485.1 /DEF=Homo sapiens adenine phosphoribosyltransferase (APRT), mRNA. /FEA=mRNA /GEN=APRT /PROD=adenine phosphoribosyltransferase /DB_XREF=gi:4502170 /UG=Hs.28914 adenine phosphoribosyltransferase /FL=gb:NM_000485.1 NM_000485 adenine phosphoribosyltransferase APRT 353 NM_000485 /// NM_001030018 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006168 // adenine salvage // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002055 // adenine binding // inferred from electronic annotation /// 0003999 // adenine phosphoribosyltransferase activity // traceable author statement /// 0016208 // AMP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 203220_s_at AI951720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI951720 /FEA=EST /DB_XREF=gi:5744030 /DB_XREF=est:wv38f09.x1 /CLONE=IMAGE:2531849 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1 AI951720 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203221_at AI758763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI758763 /FEA=EST /DB_XREF=gi:5152488 /DB_XREF=est:ty24a06.x1 /CLONE=IMAGE:2279986 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1 AI758763 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203222_s_at NM_005077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005077.1 /DEF=Homo sapiens transducin-like enhancer of split 1, homolog of Drosophila E(sp1) (TLE1), mRNA. /FEA=mRNA /GEN=TLE1 /PROD=transducin-like enhancer of split 1, homolog ofDrosophila E(sp1) /DB_XREF=gi:4827027 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1 NM_005077 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203223_at NM_004703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004703.1 /DEF=Homo sapiens rabaptin-5 (RAB5EP), mRNA. /FEA=mRNA /GEN=RAB5EP /PROD=rabaptin-5 /DB_XREF=gi:4759005 /UG=Hs.326056 rabaptin-5 /FL=gb:NM_004703.1 NM_004703 rabaptin, RAB GTPase binding effector protein 1 RABEP1 9135 NM_001083585 /// NM_001291581 /// NM_001291582 /// NM_004703 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 203224_at BF340123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF340123 /FEA=EST /DB_XREF=gi:11286585 /DB_XREF=est:602037283F1 /CLONE=IMAGE:4185212 /UG=Hs.37558 hypothetical protein FLJ11149 /FL=gb:NM_018339.1 BF340123 riboflavin kinase RFK 55312 NM_018339 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0009231 // riboflavin biosynthetic process // non-traceable author statement /// 0009398 // FMN biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008531 // riboflavin kinase activity // non-traceable author statement /// 0008531 // riboflavin kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203225_s_at NM_018339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018339.1 /DEF=Homo sapiens hypothetical protein FLJ11149 (FLJ11149), mRNA. /FEA=mRNA /GEN=FLJ11149 /PROD=hypothetical protein FLJ11149 /DB_XREF=gi:8922898 /UG=Hs.37558 hypothetical protein FLJ11149 /FL=gb:NM_018339.1 NM_018339 riboflavin kinase RFK 55312 NM_018339 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0009231 // riboflavin biosynthetic process // non-traceable author statement /// 0009398 // FMN biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008531 // riboflavin kinase activity // non-traceable author statement /// 0008531 // riboflavin kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203226_s_at AL514076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL514076 /FEA=EST /DB_XREF=gi:12777570 /DB_XREF=est:AL514076 /CLONE=CL0BA004ZB05 (5 prime) /UG=Hs.50984 sarcoma amplified sequence /FL=gb:U01160.1 gb:NM_005981.1 AL514076 tetraspanin 31 TSPAN31 6302 NM_005981 /// XM_005269074 0008284 // positive regulation of cell proliferation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 203227_s_at NM_005981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005981.1 /DEF=Homo sapiens sarcoma amplified sequence (SAS), mRNA. /FEA=mRNA /GEN=SAS /PROD=sarcoma amplified sequence /DB_XREF=gi:5174666 /UG=Hs.50984 sarcoma amplified sequence /FL=gb:U01160.1 gb:NM_005981.1 NM_005981 tetraspanin 31 TSPAN31 6302 NM_005981 /// XM_005269074 0008284 // positive regulation of cell proliferation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 203228_at NM_002573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002573.1 /DEF=Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD) (PAFAH1B3), mRNA. /FEA=mRNA /GEN=PAFAH1B3 /PROD=platelet-activating factor acetylhydrolase,isoform Ib, gamma subunit (29kD) /DB_XREF=gi:4505586 /UG=Hs.6793 platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD) /FL=gb:D63391.1 gb:BC003016.1 gb:NM_002573.1 NM_002573 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) PAFAH1B3 5050 NM_001145939 /// NM_001145940 /// NM_002573 0006629 // lipid metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203229_s_at NM_003993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003993.1 /DEF=Homo sapiens CDC-like kinase 2 (CLK2), transcript variant phclk2, mRNA. /FEA=mRNA /GEN=CLK2 /PROD=CDC-like kinase 2 isoform hclk2 /DB_XREF=gi:4502882 /UG=Hs.73986 CDC-like kinase 2 /FL=gb:NM_003993.1 gb:L29218.1 NM_003993 CDC-like kinase 2 CLK2 1196 NM_001291 /// NM_001294338 /// NM_001294339 /// NM_003993 /// XM_005244876 /// XM_005244878 /// XM_005244879 /// XM_005276742 /// XM_005276744 /// XM_005276745 /// XR_241067 /// XR_254196 0006468 // protein phosphorylation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203230_at AF006011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006011.1 /DEF=Homo sapiens dishevelled 1 (DVL1) mRNA, complete cds. /FEA=mRNA /GEN=DVL1 /PROD=dishevelled 1 /DB_XREF=gi:2291005 /UG=Hs.74375 dishevelled 1 (homologous to Drosophila dsh) /FL=gb:U46461.1 gb:AF006011.1 gb:NM_004421.1 AF006011 dishevelled segment polarity protein 1 DVL1 1855 NM_004421 /// NM_181870 /// NM_182779 /// XM_005244731 /// XM_005244732 /// XM_005244733 0001505 // regulation of neurotransmitter levels // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0007507 // heart development // non-traceable author statement /// 0007528 // neuromuscular junction development // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from expression pattern /// 0022007 // convergent extension involved in neural plate elongation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0035372 // protein localization to microtubule // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048668 // collateral sprouting // not recorded /// 0048675 // axon extension // not recorded /// 0048813 // dendrite morphogenesis // not recorded /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0060026 // convergent extension // not recorded /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // not recorded /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005874 // microtubule // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // not recorded /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // not recorded /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0030426 // growth cone // not recorded /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043025 // neuronal cell body // not recorded /// 0045202 // synapse // not recorded /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0048365 // Rac GTPase binding // not recorded 203231_s_at AW235612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW235612 /FEA=EST /DB_XREF=gi:6568001 /DB_XREF=est:xn20e02.x1 /CLONE=IMAGE:2694266 /UG=Hs.74520 spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) /FL=gb:NM_000332.1 AW235612 ataxin 1 ATXN1 6310 NM_000332 /// NM_001128164 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay 203232_s_at NM_000332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000332.1 /DEF=Homo sapiens spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) (SCA1), mRNA. /FEA=mRNA /GEN=SCA1 /PROD=ataxin 1 /DB_XREF=gi:4506792 /UG=Hs.74520 spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) /FL=gb:NM_000332.1 NM_000332 ataxin 1 ATXN1 6310 NM_000332 /// NM_001128164 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay 203233_at NM_000418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000418.1 /DEF=Homo sapiens interleukin 4 receptor (IL4R), mRNA. /FEA=mRNA /GEN=IL4R /PROD=interleukin 4 receptor precursor /DB_XREF=gi:4557668 /UG=Hs.75545 interleukin 4 receptor /FL=gb:NM_000418.1 NM_000418 interleukin 4 receptor IL4R 3566 NM_000418 /// NM_001008699 /// NM_001257406 /// NM_001257407 /// NM_001257997 /// XM_005255305 /// XM_005255308 /// XM_005255309 /// XM_006721043 0002376 // immune system process // inferred from electronic annotation /// 0002532 // production of molecular mediator involved in inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0035771 // interleukin-4-mediated signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004913 // interleukin-4 receptor activity // traceable author statement /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from reviewed computational analysis 203234_at NM_003364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003364.1 /DEF=Homo sapiens uridine phosphorylase (UP), mRNA. /FEA=mRNA /GEN=UP /PROD=uridine phosphorylase /DB_XREF=gi:4507838 /UG=Hs.77573 uridine phosphorylase /FL=gb:BC001405.1 gb:NM_003364.1 NM_003364 uridine phosphorylase 1 UPP1 7378 NM_001287426 /// NM_001287428 /// NM_001287429 /// NM_001287430 /// NM_003364 /// NM_181597 /// NR_109837 /// XM_005249838 /// XM_006715771 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009166 // nucleotide catabolic process // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044206 // UMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046108 // uridine metabolic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004850 // uridine phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation 203235_at NM_003249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003249.1 /DEF=Homo sapiens thimet oligopeptidase 1 (THOP1), mRNA. /FEA=mRNA /GEN=THOP1 /PROD=thimet oligopeptidase 1 /DB_XREF=gi:4507490 /UG=Hs.78769 thimet oligopeptidase 1 /FL=gb:U29366.1 gb:BC000583.1 gb:BC002391.1 gb:BC000135.2 gb:NM_003249.1 NM_003249 thimet oligopeptidase 1 THOP1 7064 NM_003249 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203236_s_at NM_009587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_009587.1 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 9 (galectin 9) (LGALS9), transcript variant long, mRNA. /FEA=mRNA /GEN=LGALS9 /PROD=galectin 9, long isoform /DB_XREF=gi:6806889 /UG=Hs.81337 lectin, galactoside-binding, soluble, 9 (galectin 9) /FL=gb:AB006782.1 gb:NM_009587.1 NM_009587 lectin, galactoside-binding, soluble, 9 LGALS9 3965 NM_002308 /// NM_009587 /// NR_024043 /// XM_006721892 /// XM_006721893 /// XM_006721894 /// XM_006721895 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005534 // galactose binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from direct assay 203237_s_at AW139152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139152 /FEA=EST /DB_XREF=gi:6143470 /DB_XREF=est:UI-H-BI1-aet-c-11-0-UI.s1 /CLONE=IMAGE:2720277 /UG=Hs.8546 Notch (Drosophila) homolog 3 /FL=gb:U97669.1 gb:NM_000435.1 AW139152 notch 3 NOTCH3 4854 NM_000435 /// XM_005259924 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0072104 // glomerular capillary formation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 203238_s_at NM_000435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000435.1 /DEF=Homo sapiens Notch (Drosophila) homolog 3 (NOTCH3), mRNA. /FEA=mRNA /GEN=NOTCH3 /PROD=Notch (Drosophila) homolog 3 /DB_XREF=gi:4557798 /UG=Hs.8546 Notch (Drosophila) homolog 3 /FL=gb:U97669.1 gb:NM_000435.1 NM_000435 notch 3 NOTCH3 4854 NM_000435 /// XM_005259924 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0072104 // glomerular capillary formation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 203239_s_at NM_014516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014516.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 3 (CNOT3), mRNA. /FEA=mRNA /GEN=CNOT3 /PROD=CCR4-NOT transcription complex, subunit 3 /DB_XREF=gi:7657386 /UG=Hs.108300 CCR4-NOT transcription complex, subunit 3 /FL=gb:AB014591.1 gb:NM_014516.1 NM_014516 CCR4-NOT transcription complex, subunit 3 CNOT3 4849 NM_014516 /// XM_005258956 /// XM_005258957 /// XM_005258958 /// XM_005258959 /// XM_005277076 /// XM_005277077 /// XM_005277078 /// XM_005277079 /// XM_005277266 /// XM_005277267 /// XM_005277268 /// XM_005277269 /// XM_005278279 /// XM_005278280 /// XM_005278281 /// XM_005278282 /// XM_006725771 /// XM_006725772 /// XM_006725773 /// XM_006725774 /// XM_006725872 /// XM_006725873 /// XM_006725874 /// XM_006725875 /// XM_006725960 /// XM_006725961 /// XM_006725962 /// XM_006725963 /// XM_006726059 /// XM_006726060 /// XM_006726061 /// XM_006726062 /// XM_006726160 /// XM_006726161 /// XM_006726162 /// XM_006726163 /// XM_006726197 /// XM_006726198 /// XM_006726199 /// XM_006726200 /// XR_243935 /// XR_243936 /// XR_254258 /// XR_254259 /// XR_254309 /// XR_254310 /// XR_254515 /// XR_254516 /// XR_430951 /// XR_430952 /// XR_430984 /// XR_430985 /// XR_431004 /// XR_431005 /// XR_431023 /// XR_431024 /// XR_431054 /// XR_431055 /// XR_431065 /// XR_431066 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203240_at NM_003890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003890.1 /DEF=Homo sapiens IgG Fc binding protein (FC(GAMMA)BP) mRNA. /FEA=mRNA /GEN=FC(GAMMA)BP /PROD=IgG Fc binding protein /DB_XREF=gi:4503680 /UG=Hs.111732 Fc fragment of IgG binding protein /FL=gb:D84239.1 gb:NM_003890.1 NM_003890 Fc fragment of IgG binding protein FCGBP 8857 NM_003890 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203241_at NM_003369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003369.1 /DEF=Homo sapiens UV radiation resistance associated gene (UVRAG), mRNA. /FEA=mRNA /GEN=UVRAG /PROD=UV radiation resistance associated gene /DB_XREF=gi:4507860 /UG=Hs.13137 UV radiation resistance associated gene /FL=gb:NM_003369.1 gb:AB012958.1 NM_003369 UV radiation resistance associated UVRAG 7405 NM_003369 /// XM_005274209 /// XM_006718673 /// XM_006718674 /// XM_006718675 0006281 // DNA repair // traceable author statement /// 0010508 // positive regulation of autophagy // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 203242_s_at BG054550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG054550 /FEA=EST /DB_XREF=gi:12511559 /DB_XREF=est:7o46a11.x1 /CLONE=IMAGE:3576885 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) /FL=gb:AF061258.1 gb:NM_006457.1 BG054550 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203243_s_at NM_006457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006457.1 /DEF=Homo sapiens LIM protein (similar to rat protein kinase C-binding enigma) (LIM), mRNA. /FEA=mRNA /GEN=LIM /PROD=LIM protein (similar to rat protein kinaseC-binding enigma) /DB_XREF=gi:5453713 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) /FL=gb:AF061258.1 gb:NM_006457.1 NM_006457 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203244_at NM_000319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000319.1 /DEF=Homo sapiens peroxisome receptor 1 (PXR1), mRNA. /FEA=mRNA /GEN=PXR1 /PROD=peroxisome receptor 1 /DB_XREF=gi:4506346 /UG=Hs.158084 peroxisome receptor 1 /FL=gb:NM_000319.1 gb:U19721.1 NM_000319 peroxisomal biogenesis factor 5 PEX5 5830 NM_000319 /// NM_001131023 /// NM_001131024 /// NM_001131025 /// NM_001131026 /// XM_005253451 /// XM_005253452 /// XM_005253453 /// XM_005253455 /// XM_006719129 /// XM_006719130 /// XM_006719131 /// XM_006719132 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from genetic interaction /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // non-traceable author statement /// 0016560 // protein import into peroxisome matrix, docking // inferred from direct assay /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0048468 // cell development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from mutant phenotype /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 203245_s_at BC002791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002791.1 /DEF=Homo sapiens, homologous to yeast nitrogen permease (candidate tumor suppressor), clone MGC:3527, mRNA, complete cds. /FEA=mRNA /PROD=homologous to yeast nitrogen permease (candidatetumor suppressor) /DB_XREF=gi:12803888 /UG=Hs.169780 homologous to yeast nitrogen permease (candidate tumor suppressor) /FL=gb:BC002791.1 gb:AF040707.1 gb:NM_006545.1 BC002791 long intergenic non-protein coding RNA 94 LINC00094 266655 NR_002800 /// NR_015427 203246_s_at NM_006545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006545.1 /DEF=Homo sapiens homologous to yeast nitrogen permease (candidate tumor suppressor) (NPR2L), mRNA. /FEA=mRNA /GEN=NPR2L /PROD=homologous to yeast nitrogen permease (candidatetumor suppressor) /DB_XREF=gi:5729948 /UG=Hs.169780 homologous to yeast nitrogen permease (candidate tumor suppressor) /FL=gb:BC002791.1 gb:AF040707.1 gb:NM_006545.1 NM_006545 nitrogen permease regulator-like 2 (S. cerevisiae) NPRL2 10641 NM_006545 /// XM_005264806 /// XM_005264808 /// XM_006712937 0006468 // protein phosphorylation // inferred from direct assay /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203247_s_at BC003566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003566.1 /DEF=Homo sapiens, zinc finger protein 24 (KOX 17), clone MGC:2057, mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 24 (KOX 17) /DB_XREF=gi:13097725 /UG=Hs.183593 zinc finger protein 24 (KOX 17) /FL=gb:BC003566.1 gb:U68536.1 gb:AF038964.1 gb:NM_006965.1 BC003566 zinc finger protein 24 ZNF24 7572 NM_006965 /// XM_005258341 /// XM_005258342 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203248_at NM_006965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006965.1 /DEF=Homo sapiens zinc finger protein 24 (KOX 17) (ZNF24), mRNA. /FEA=mRNA /GEN=ZNF24 /PROD=zinc finger protein 24 (KOX 17) /DB_XREF=gi:5902161 /UG=Hs.183593 zinc finger protein 24 (KOX 17) /FL=gb:BC003566.1 gb:U68536.1 gb:AF038964.1 gb:NM_006965.1 NM_006965 zinc finger protein 24 ZNF24 7572 NM_006965 /// XM_005258341 /// XM_005258342 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203249_at AB002386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002386.1 /DEF=Human mRNA for KIAA0388 gene, complete cds. /FEA=mRNA /GEN=KIAA0388 /DB_XREF=gi:2224716 /UG=Hs.194669 enhancer of zeste (Drosophila) homolog 1 /FL=gb:U50315.1 gb:AB002386.1 gb:NM_001991.1 AB002386 enhancer of zeste 1 polycomb repressive complex 2 subunit EZH1 2145 NM_001991 /// XM_005257144 /// XM_005257145 /// XM_005257146 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from electronic annotation 203250_at NM_014892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014892.1 /DEF=Homo sapiens KIAA1116 protein (KIAA1116), mRNA. /FEA=mRNA /GEN=KIAA1116 /PROD=KIAA1116 protein /DB_XREF=gi:7662491 /UG=Hs.227602 KIAA1116 protein /FL=gb:AB029039.1 gb:NM_014892.1 NM_014892 SR-related CTD-associated factor 8 SCAF8 22828 NM_001286188 /// NM_001286189 /// NM_001286194 /// NM_001286199 /// NM_014892 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0043175 // RNA polymerase core enzyme binding // inferred from physical interaction 203252_at NM_005851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005851.1 /DEF=Homo sapiens tumor suppressor deleted in oral cancer-related 1 (DOC-1R), mRNA. /FEA=mRNA /GEN=DOC-1R /PROD=tumor suppressor deleted in oral cancer-related1 /DB_XREF=gi:5031668 /UG=Hs.25664 tumor suppressor deleted in oral cancer-related 1 /FL=gb:BC002850.1 gb:AF089814.1 gb:NM_005851.1 NM_005851 cyclin-dependent kinase 2 associated protein 2 CDK2AP2 10263 NM_001271849 /// NM_005851 /// NR_073484 0016310 // phosphorylation // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation 203253_s_at NM_015216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015216.1 /DEF=Homo sapiens KIAA0433 protein (KIAA0433), mRNA. /FEA=mRNA /GEN=KIAA0433 /PROD=KIAA0433 protein /DB_XREF=gi:7662117 /UG=Hs.26179 KIAA0433 protein /FL=gb:NM_015216.1 NM_015216 diphosphoinositol pentakisphosphate kinase 2 PPIP5K2 23262 NM_001276277 /// NM_001281471 /// NM_015216 /// NR_074081 /// XM_005271935 /// XM_005271936 /// XM_005271938 /// XM_005277534 /// XM_005277535 /// XM_005277536 /// XM_005277538 /// XM_005277539 /// XM_005277541 /// XM_006714576 /// XM_006714577 /// XM_006714578 0006020 // inositol metabolic process // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000827 // inositol-1,3,4,5,6-pentakisphosphate kinase activity // inferred from sequence or structural similarity /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from sequence or structural similarity /// 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033857 // diphosphoinositol-pentakisphosphate kinase activity // inferred from sequence or structural similarity /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation 203254_s_at NM_006289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006289.1 /DEF=Homo sapiens talin (TLN), mRNA. /FEA=mRNA /GEN=TLN /PROD=talin /DB_XREF=gi:5454129 /UG=Hs.278559 talin /FL=gb:AF078828.1 gb:NM_006289.1 gb:AF177198.1 NM_006289 talin 1 TLN1 7094 NM_006289 /// XM_005251564 /// XM_006716852 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0001726 // ruffle // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred by curator /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0005925 // focal adhesion // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 203255_at NM_018693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018693.1 /DEF=Homo sapiens vitiligo-associated protein VIT-1 (VIT1), mRNA. /FEA=mRNA /GEN=VIT1 /PROD=vitiligo-associated protein VIT-1 /DB_XREF=gi:10048403 /UG=Hs.284289 vitiligo-associated protein VIT-1 /FL=gb:NM_018693.1 gb:AF264714.1 NM_018693 F-box protein 11 FBXO11 80204 NM_001190274 /// NM_012167 /// NM_018693 /// NM_025133 /// XM_005264572 /// XM_005264573 /// XM_005264574 0006464 // cellular protein modification process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0035246 // peptidyl-arginine N-methylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016274 // protein-arginine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203256_at NM_001793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001793.1 /DEF=Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3), mRNA. /FEA=mRNA /GEN=CDH3 /PROD=cadherin 3, type 1, P-cadherin (placental) /DB_XREF=gi:4502722 /UG=Hs.2877 cadherin 3, type 1, P-cadherin (placental) /FL=gb:NM_001793.1 NM_001793 cadherin 3, type 1, P-cadherin (placental) CDH3 1001 NM_001793 0001895 // retina homeostasis // inferred from mutant phenotype /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010838 // positive regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022405 // hair cycle process // inferred from mutant phenotype /// 0031424 // keratinization // inferred from mutant phenotype /// 0032773 // positive regulation of monophenol monooxygenase activity // inferred from mutant phenotype /// 0032912 // negative regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0048023 // positive regulation of melanin biosynthetic process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051796 // negative regulation of catagen // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060901 // regulation of hair cycle by canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902910 // positive regulation of melanosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203257_s_at NM_024113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024113.1 /DEF=Homo sapiens hypothetical protein MGC4707 (MGC4707), mRNA. /FEA=mRNA /GEN=MGC4707 /PROD=hypothetical protein MGC4707 /DB_XREF=gi:13129129 /UG=Hs.291003 hypothetical protein MGC4707 /FL=gb:BC001860.1 gb:NM_024113.1 NM_024113 chromosome 11 open reading frame 49 C11orf49 79096 NM_001003676 /// NM_001003677 /// NM_001003678 /// NM_001278222 /// NM_024113 /// NR_103471 /// NR_103472 /// XM_006718315 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 203258_at NM_006442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006442.1 /DEF=Homo sapiens DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), mRNA. /FEA=mRNA /GEN=DRAP1 /PROD=DR1-associated protein 1 (negative cofactor 2alpha) /DB_XREF=gi:5453635 /UG=Hs.295362 DR1-associated protein 1 (negative cofactor 2 alpha) /FL=gb:U41843.1 gb:NM_006442.1 NM_006442 DR1-associated protein 1 (negative cofactor 2 alpha) DRAP1 10589 NM_006442 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203259_s_at BC001671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001671.1 /DEF=Homo sapiens, Similar to CGI-130 protein, clone MGC:2442, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CGI-130 protein /DB_XREF=gi:12804520 /UG=Hs.32826 CGI-130 protein /FL=gb:BC001671.1 gb:AF151888.1 gb:NM_016063.1 BC001671 HD domain containing 2 HDDC2 51020 NM_016063 /// XR_245538 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203260_at NM_016063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016063.1 /DEF=Homo sapiens CGI-130 protein (LOC51020), mRNA. /FEA=mRNA /GEN=LOC51020 /PROD=CGI-130 protein /DB_XREF=gi:7705623 /UG=Hs.32826 CGI-130 protein /FL=gb:BC001671.1 gb:AF151888.1 gb:NM_016063.1 NM_016063 HD domain containing 2 HDDC2 51020 NM_016063 /// XR_245538 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203261_at NM_006571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006571.1 /DEF=Homo sapiens novel RGD-containing protein (WS-3), mRNA. /FEA=mRNA /GEN=WS-3 /PROD=novel RGD-containing protein /DB_XREF=gi:5730115 /UG=Hs.39913 novel RGD-containing protein /FL=gb:D84145.1 gb:NM_006571.1 NM_006571 dynactin 6 DCTN6 10671 NM_006571 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation 0045502 // dynein binding // inferred from electronic annotation 203262_s_at NM_004699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004699.1 /DEF=Homo sapiens DNA segment on chromosome X (unique) 9928 expressed sequence (DXS9928E), mRNA. /FEA=mRNA /GEN=DXS9928E /PROD=XAP-5 protein /DB_XREF=gi:4758219 /UG=Hs.54277 DNA segment on chromosome X (unique) 9928 expressed sequence /FL=gb:BC000028.1 gb:D83260.1 gb:AD001530.1 gb:NM_004699.1 NM_004699 family with sequence similarity 50, member A FAM50A 9130 NM_004699 0007283 // spermatogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 203263_s_at AI625739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI625739 /FEA=EST /DB_XREF=gi:4650670 /DB_XREF=est:ty65g05.x1 /CLONE=IMAGE:2283992 /UG=Hs.54697 Cdc42 guanine exchange factor (GEF) 9 /FL=gb:NM_015185.1 AI625739 Cdc42 guanine nucleotide exchange factor (GEF) 9 ARHGEF9 23229 NM_001173479 /// NM_001173480 /// NM_015185 /// XM_005262249 /// XM_005262250 /// XM_005262251 /// XM_005262252 /// XM_005262253 /// XM_006724636 /// XM_006724637 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203264_s_at NM_015185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015185.1 /DEF=Homo sapiens Cdc42 guanine exchange factor (GEF) 9 (ARHGEF9), mRNA. /FEA=mRNA /GEN=ARHGEF9 /PROD=Cdc42 guanine exchange factor (GEF) 9 /DB_XREF=gi:7662107 /UG=Hs.54697 Cdc42 guanine exchange factor (GEF) 9 /FL=gb:NM_015185.1 NM_015185 Cdc42 guanine nucleotide exchange factor (GEF) 9 ARHGEF9 23229 NM_001173479 /// NM_001173480 /// NM_015185 /// XM_005262249 /// XM_005262250 /// XM_005262251 /// XM_005262252 /// XM_005262253 /// XM_006724636 /// XM_006724637 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203265_s_at AA810268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA810268 /FEA=EST /DB_XREF=gi:2879627 /DB_XREF=est:od14f07.s1 /CLONE=IMAGE:1367941 /UG=Hs.75217 mitogen-activated protein kinase kinase 4 /FL=gb:NM_003010.1 gb:L36870.1 gb:U17743.1 AA810268 mitogen-activated protein kinase kinase 4 MAP2K4 6416 NM_001281435 /// NM_003010 /// XM_005256753 /// XM_005256755 /// XM_006721568 0000165 // MAPK cascade // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 203266_s_at NM_003010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003010.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), mRNA. /FEA=mRNA /GEN=MAP2K4 /PROD=mitogen-activated protein kinase kinase 4 /DB_XREF=gi:4506888 /UG=Hs.75217 mitogen-activated protein kinase kinase 4 /FL=gb:NM_003010.1 gb:L36870.1 gb:U17743.1 NM_003010 mitogen-activated protein kinase kinase 4 MAP2K4 6416 NM_001281435 /// NM_003010 /// XM_005256753 /// XM_005256755 /// XM_006721568 0000165 // MAPK cascade // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 203267_s_at BF223206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223206 /FEA=EST /DB_XREF=gi:11130383 /DB_XREF=est:7q30e06.x1 /CLONE=IMAGE:3699923 /UG=Hs.78582 developmentally regulated GTP-binding protein 2 /FL=gb:BC000493.1 gb:NM_001388.1 BF223206 developmentally regulated GTP binding protein 2 DRG2 1819 NM_001388 /// XM_005256499 /// XM_005256500 /// XM_006721468 0007165 // signal transduction // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 203268_s_at NM_001388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001388.1 /DEF=Homo sapiens developmentally regulated GTP-binding protein 2 (DRG2), mRNA. /FEA=mRNA /GEN=DRG2 /PROD=developmentally regulated GTP-binding protein 2 /DB_XREF=gi:4557536 /UG=Hs.78582 developmentally regulated GTP-binding protein 2 /FL=gb:BC000493.1 gb:NM_001388.1 NM_001388 developmentally regulated GTP binding protein 2 DRG2 1819 NM_001388 /// XM_005256499 /// XM_005256500 /// XM_006721468 0007165 // signal transduction // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 203269_at NM_003580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003580.1 /DEF=Homo sapiens neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), mRNA. /FEA=mRNA /GEN=NSMAF /PROD=neutral sphingomyelinase (N-SMase) activationassociated factor /DB_XREF=gi:4505464 /UG=Hs.78687 neutral sphingomyelinase (N-SMase) activation associated factor /FL=gb:NM_003580.1 NM_003580 neutral sphingomyelinase (N-SMase) activation associated factor NSMAF 8439 NM_001144772 /// NM_003580 0006672 // ceramide metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016230 // sphingomyelin phosphodiesterase activator activity // inferred from electronic annotation 203270_at NM_012145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012145.1 /DEF=Homo sapiens deoxythymidylate kinase (thymidylate kinase) (DTYMK), mRNA. /FEA=mRNA /GEN=DTYMK /PROD=deoxythymidylate kinase (thymidylate kinase) /DB_XREF=gi:6912339 /UG=Hs.79006 deoxythymidylate kinase (thymidylate kinase) /FL=gb:BC001827.1 gb:L16991.1 gb:NM_012145.1 NM_012145 deoxythymidylate kinase (thymidylate kinase) DTYMK 1841 NM_001165031 /// NM_012145 /// NR_033255 0006233 // dTDP biosynthetic process // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0046940 // nucleoside monophosphate phosphorylation // not recorded /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004798 // thymidylate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050145 // nucleoside phosphate kinase activity // not recorded 203271_s_at NM_005148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005148.1 /DEF=Homo sapiens unc119 (C.elegans) homolog (UNC119), mRNA. /FEA=mRNA /GEN=UNC119 /PROD=unc119 (C.elegans) homolog /DB_XREF=gi:4827047 /UG=Hs.81728 unc119 (C.elegans) homolog /FL=gb:U40998.1 gb:AF028788.1 gb:NM_005148.1 NM_005148 unc-119 homolog (C. elegans) UNC119 9094 NM_005148 /// NM_054035 0006810 // transport // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 1900186 // negative regulation of clathrin-mediated endocytosis // inferred from sequence or structural similarity /// 2001287 // negative regulation of caveolin-mediated endocytosis // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 203272_s_at BF308548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF308548 /FEA=EST /DB_XREF=gi:11255776 /DB_XREF=est:601890403F1 /CLONE=IMAGE:4131457 /UG=Hs.8186 lung cancer candidate /FL=gb:AF055479.1 gb:NM_007275.1 BF308548 tumor suppressor candidate 2 TUSC2 11334 NM_007275 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032618 // interleukin-15 production // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0071609 // chemokine (C-C motif) ligand 5 production // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 203273_s_at NM_007275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007275.1 /DEF=Homo sapiens lung cancer candidate (FUS1), mRNA. /FEA=mRNA /GEN=FUS1 /PROD=lung cancer candidate /DB_XREF=gi:6005759 /UG=Hs.8186 lung cancer candidate /FL=gb:AF055479.1 gb:NM_007275.1 NM_007275 tumor suppressor candidate 2 TUSC2 11334 NM_007275 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032618 // interleukin-15 production // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0071609 // chemokine (C-C motif) ligand 5 production // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 203274_at NM_012151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012151.2 /DEF=Homo sapiens coagulation factor VIII-associated (intronic transcript) (F8A), mRNA. /FEA=mRNA /GEN=F8A /PROD=coagulation factor VIII-associated protein /DB_XREF=gi:12056462 /UG=Hs.83363 coagulation factor VIII-associated (intronic transcript) /FL=gb:NM_012151.2 NM_012151 coagulation factor VIII-associated 1 /// coagulation factor VIII-associated 2 /// coagulation factor VIII-associated 3 F8A1 /// F8A2 /// F8A3 8263 /// 474383 /// 474384 NM_001007523 /// NM_001007524 /// NM_012151 0005634 // nucleus // inferred from direct assay 203275_at NM_002199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002199.2 /DEF=Homo sapiens interferon regulatory factor 2 (IRF2), mRNA. /FEA=mRNA /GEN=IRF2 /PROD=interferon regulatory factor 2 /DB_XREF=gi:4755144 /UG=Hs.83795 interferon regulatory factor 2 /FL=gb:NM_002199.2 NM_002199 interferon regulatory factor 2 IRF2 3660 NM_002199 /// XM_005262984 /// XM_005262986 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 203276_at NM_005573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005573.1 /DEF=Homo sapiens lamin B1 (LMNB1), mRNA. /FEA=mRNA /GEN=LMNB1 /PROD=lamin B1 /DB_XREF=gi:5031876 /UG=Hs.89497 lamin B1 /FL=gb:M34458.1 gb:NM_005573.1 NM_005573 lamin B1 LMNB1 4001 NM_001198557 /// NM_005573 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005638 // lamin filament // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation 203277_at NM_004401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004401.1 /DEF=Homo sapiens DNA fragmentation factor, 45 kD, alpha polypeptide (DFFA), mRNA. /FEA=mRNA /GEN=DFFA /PROD=DNA fragmentation factor, 45 kD, alphapolypeptide /DB_XREF=gi:4758147 /UG=Hs.105658 DNA fragmentation factor, 45 kD, alpha polypeptide /FL=gb:BC000037.1 gb:U91985.1 gb:NM_004401.1 NM_004401 DNA fragmentation factor, 45kDa, alpha polypeptide DFFA 1676 NM_004401 /// NM_213566 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1902511 // negative regulation of apoptotic DNA fragmentation // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004536 // deoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203278_s_at NM_016621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016621.1 /DEF=Homo sapiens hypothetical protein (LOC51317), mRNA. /FEA=mRNA /GEN=LOC51317 /PROD=hypothetical protein /DB_XREF=gi:7706159 /UG=Hs.106826 KIAA1696 protein /FL=gb:AF208848.1 gb:NM_016621.1 NM_016621 PHD finger protein 21A PHF21A 51317 NM_001101802 /// NM_016621 /// XM_005252962 /// XM_005252963 /// XM_005252964 /// XM_005252965 /// XM_005252967 /// XM_005252970 /// XM_006718247 /// XM_006718248 /// XR_242810 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203279_at NM_014674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014674.1 /DEF=Homo sapiens KIAA0212 gene product (KIAA0212), mRNA. /FEA=mRNA /GEN=KIAA0212 /PROD=KIAA0212 gene product /DB_XREF=gi:7662001 /UG=Hs.154332 KIAA0212 gene product /FL=gb:D86967.1 gb:NM_014674.1 NM_014674 ER degradation enhancer, mannosidase alpha-like 1 EDEM1 9695 NM_014674 /// XM_006713424 /// XM_006713425 /// XR_245168 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 203280_at NM_014649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014649.1 /DEF=Homo sapiens KIAA0138 gene product (KIAA0138), mRNA. /FEA=mRNA /GEN=KIAA0138 /PROD=KIAA0138 gene product /DB_XREF=gi:7661935 /UG=Hs.159384 KIAA0138 gene product /FL=gb:D50928.1 gb:NM_014649.1 NM_014649 scaffold attachment factor B2 SAFB2 9667 NM_014649 /// XM_005259688 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203281_s_at NM_003335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003335.1 /DEF=Homo sapiens ubiquitin-activating enzyme E1-like (UBE1L), mRNA. /FEA=mRNA /GEN=UBE1L /PROD=ubiquitin-activating enzyme E1-like /DB_XREF=gi:4507766 /UG=Hs.16695 ubiquitin-activating enzyme E1-like /FL=gb:NM_003335.1 gb:L13852.1 NM_003335 microRNA 5193 /// ubiquitin-like modifier activating enzyme 7 MIR5193 /// UBA7 7318 /// 100847079 NM_003335 /// NR_049825 /// XM_005265430 /// XM_006713321 0006464 // cellular protein modification process // inferred from direct assay /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // not recorded /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // not recorded /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay 203282_at NM_000158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000158.1 /DEF=Homo sapiens glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) (GBE1), mRNA. /FEA=mRNA /GEN=GBE1 /PROD=glucan (1,4-alpha-), branching enzyme 1(glycogen branching enzyme) /DB_XREF=gi:4557618 /UG=Hs.1691 glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) /FL=gb:L07956.1 gb:NM_000158.1 NM_000158 glucan (1,4-alpha-), branching enzyme 1 GBE1 2632 NM_000158 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003844 // 1,4-alpha-glucan branching enzyme activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043169 // cation binding // inferred from electronic annotation 203283_s_at AK023260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023260.1 /DEF=Homo sapiens cDNA FLJ13198 fis, clone NT2RP3004454, highly similar to Homo sapiens mRNA for KIAA0448 protein. /FEA=mRNA /DB_XREF=gi:10435114 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1 AK023260 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203284_s_at AW151887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW151887 /FEA=EST /DB_XREF=gi:6199872 /DB_XREF=est:xf72c12.x1 /CLONE=IMAGE:2623606 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1 AW151887 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203285_s_at NM_012262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012262.2 /DEF=Homo sapiens heparan sulfate 2-O-sulfotransferase (HS2ST1), mRNA. /FEA=mRNA /GEN=HS2ST1 /PROD=heparan sulfate 2-O-sulfotransferase 1 /DB_XREF=gi:12545388 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1 NM_012262 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203286_at NM_014901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014901.1 /DEF=Homo sapiens KIAA1100 protein (KIAA1100), mRNA. /FEA=mRNA /GEN=KIAA1100 /PROD=KIAA1100 protein /DB_XREF=gi:7662485 /UG=Hs.179946 KIAA1100 protein /FL=gb:AB029023.1 gb:NM_014901.1 NM_014901 ring finger protein 44 RNF44 22838 NM_014901 /// XM_005265840 /// XM_005265841 /// XM_005265842 /// XM_005265843 /// XM_005265844 /// XM_005265845 /// XM_006714831 /// XM_006714832 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203287_at NM_005558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005558.1 /DEF=Homo sapiens ladinin 1 (LAD1), mRNA. /FEA=mRNA /GEN=LAD1 /PROD=ladinin 1 /DB_XREF=gi:5031844 /UG=Hs.18141 ladinin 1 /FL=gb:U42408.1 gb:NM_005558.1 NM_005558 ladinin 1 LAD1 3898 NM_005558 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // traceable author statement 203288_at NM_014686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014686.1 /DEF=Homo sapiens KIAA0355 gene product (KIAA0355), mRNA. /FEA=mRNA /GEN=KIAA0355 /PROD=KIAA0355 gene product /DB_XREF=gi:7662075 /UG=Hs.186840 KIAA0355 gene product /FL=gb:AB002353.1 gb:NM_014686.1 NM_014686 KIAA0355 KIAA0355 9710 NM_014686 /// XM_005259444 203289_s_at BE791629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE791629 /FEA=EST /DB_XREF=gi:10212827 /DB_XREF=est:601585959F1 /CLONE=IMAGE:3940215 /UG=Hs.19699 Conserved gene telomeric to alpha globin cluster /FL=gb:NM_012075.1 BE791629 nitrogen permease regulator-like 3 (S. cerevisiae) NPRL3 8131 NM_001039476 /// NM_001077350 /// NM_001243247 /// NM_001243248 /// NM_001243249 /// NM_012075 0003281 // ventricular septum development // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation 203290_at NM_002122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002122.1 /DEF=Homo sapiens major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1), mRNA. /FEA=mRNA /GEN=HLA-DQA1 /PROD=major histocompatibility complex, class II, DQalpha 1 /DB_XREF=gi:4504406 /UG=Hs.198253 major histocompatibility complex, class II, DQ alpha 1 /FL=gb:M33906.1 gb:M17846.1 gb:M17847.1 gb:M26041.1 gb:M16995.1 gb:NM_002122.1 NM_002122 major histocompatibility complex, class II, DQ alpha 1 HLA-DQA1 3117 NM_002122 /// XM_003846468 /// XM_005274953 /// XM_005275108 /// XM_005275333 /// XM_005275542 /// XM_005275544 /// XM_006715079 /// XM_006725484 /// XM_006725999 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 203291_at NM_013316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013316.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 4 (CNOT4), mRNA. /FEA=mRNA /GEN=CNOT4 /PROD=CCR4-NOT transcription complex, subunit 4 /DB_XREF=gi:7019466 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:U71267.1 gb:NM_013316.1 NM_013316 CCR4-NOT transcription complex, subunit 4 CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203292_s_at NM_021729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021729.2 /DEF=Homo sapiens vacuolar protein sorting 11 (yeast homolog) (VPS11), mRNA. /FEA=mRNA /GEN=VPS11 /PROD=vacuolar protein sorting 11 (yeast homolog) /DB_XREF=gi:11141864 /UG=Hs.234282 vacuolar protein sorting 11 (yeast homolog) /FL=gb:AB027508.2 gb:NM_021729.2 gb:AF308800.1 NM_021729 vacuolar protein sorting 11 homolog (S. cerevisiae) VPS11 55823 NM_001290185 /// NM_021729 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030897 // HOPS complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203293_s_at NM_005570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005570.2 /DEF=Homo sapiens lectin, mannose-binding, 1 (LMAN1), mRNA. /FEA=mRNA /GEN=LMAN1 /PROD=lectin, mannose-binding, 1 precursor /DB_XREF=gi:10862689 /UG=Hs.287912 lectin, mannose-binding, 1 /FL=gb:NM_005570.2 gb:U09716.1 NM_005570 lectin, mannose-binding, 1 LMAN1 3998 NM_005570 0006457 // protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 203294_s_at U09716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U09716.1 /DEF=Human mannose-specific lectin (MR60) mRNA, complete cds. /FEA=mRNA /GEN=MR60 /PROD=mannose-specific lectin /DB_XREF=gi:606827 /UG=Hs.287912 lectin, mannose-binding, 1 /FL=gb:NM_005570.2 gb:U09716.1 U09716 lectin, mannose-binding, 1 LMAN1 3998 NM_005570 0006457 // protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 203295_s_at AW440492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW440492 /FEA=EST /DB_XREF=gi:6975798 /DB_XREF=est:hb91c10.x1 /CLONE=IMAGE:2890578 /UG=Hs.34114 ATPase, Na+K+ transporting, alpha 2 (+) polypeptide /FL=gb:NM_000702.1 AW440492 ATPase, Na+/K+ transporting, alpha 2 polypeptide ATP1A2 477 NM_000702 0001504 // neurotransmitter uptake // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0006814 // sodium ion transport // non-traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0040011 // locomotion // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045988 // negative regulation of striated muscle contraction // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203296_s_at NM_000702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000702.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, alpha 2 (+) polypeptide (ATP1A2), mRNA. /FEA=mRNA /GEN=ATP1A2 /PROD=ATPase, Na+K+ transporting, alpha 2 (+)polypeptide /DB_XREF=gi:4502270 /UG=Hs.34114 ATPase, Na+K+ transporting, alpha 2 (+) polypeptide /FL=gb:NM_000702.1 NM_000702 ATPase, Na+/K+ transporting, alpha 2 polypeptide ATP1A2 477 NM_000702 0001504 // neurotransmitter uptake // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0006814 // sodium ion transport // non-traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0040011 // locomotion // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045988 // negative regulation of striated muscle contraction // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203297_s_at BG029530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG029530 /FEA=EST /DB_XREF=gi:12418626 /DB_XREF=est:602297090F1 /CLONE=IMAGE:4391375 /UG=Hs.40154 jumonji (mouse) homolog /FL=gb:NM_004973.2 gb:U57592.1 BG029530 jumonji, AT rich interactive domain 2 JARID2 3720 NM_001267040 /// NM_004973 /// XM_005249089 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from sequence or structural similarity 203298_s_at NM_004973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004973.2 /DEF=Homo sapiens jumonji (mouse) homolog (JMJ), mRNA. /FEA=mRNA /GEN=JMJ /PROD=jumonji /DB_XREF=gi:11863151 /UG=Hs.40154 jumonji (mouse) homolog /FL=gb:NM_004973.2 gb:U57592.1 NM_004973 jumonji, AT rich interactive domain 2 JARID2 3720 NM_001267040 /// NM_004973 /// XM_005249089 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from sequence or structural similarity 203299_s_at AF251295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF251295.1 /DEF=Homo sapiens DC22 mRNA, complete cds. /FEA=mRNA /PROD=DC22 /DB_XREF=gi:12005731 /UG=Hs.40368 adaptor-related protein complex 1, sigma 2 subunit /FL=gb:AF251295.1 gb:BC001117.1 gb:AB015320.1 gb:NM_003916.1 AF251295 adaptor-related protein complex 1, sigma 2 subunit AP1S2 8905 NM_001272071 /// NM_003916 /// XM_005274612 /// XM_005274614 /// XR_247289 /// XR_247290 /// XR_247291 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0008565 // protein transporter activity // inferred from electronic annotation 203300_x_at NM_003916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003916.1 /DEF=Homo sapiens adaptor-related protein complex 1, sigma 2 subunit (AP1S2), mRNA. /FEA=mRNA /GEN=AP1S2 /PROD=adaptor-related protein complex 1, sigma 2subunit /DB_XREF=gi:4506956 /UG=Hs.40368 adaptor-related protein complex 1, sigma 2 subunit /FL=gb:AF251295.1 gb:BC001117.1 gb:AB015320.1 gb:NM_003916.1 NM_003916 adaptor-related protein complex 1, sigma 2 subunit AP1S2 8905 NM_001272071 /// NM_003916 /// XM_005274612 /// XM_005274614 /// XR_247289 /// XR_247290 /// XR_247291 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0008565 // protein transporter activity // inferred from electronic annotation 203301_s_at NM_021145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021145.1 /DEF=Homo sapiens cyclin D binding Myb-like transcription factor 1 (DMTF), mRNA. /FEA=mRNA /GEN=DMTF /PROD=cyclin D binding Myb-like transcription factor1 /DB_XREF=gi:10863946 /UG=Hs.5671 cyclin D binding Myb-like transcription factor 1 /FL=gb:NM_021145.1 gb:AF084530.1 NM_021145 cyclin D binding myb-like transcription factor 1 DMTF1 9988 NM_001142326 /// NM_001142327 /// NM_021145 /// NR_024549 /// NR_024550 /// XM_005250734 /// XM_006716197 /// XM_006716198 /// XM_006716199 /// XM_006716200 /// XM_006716201 /// XM_006716202 /// XM_006716203 /// XM_006716204 /// XM_006716205 /// XM_006716206 /// XR_428190 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement 203302_at NM_000788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000788.1 /DEF=Homo sapiens deoxycytidine kinase (DCK), mRNA. /FEA=mRNA /GEN=DCK /PROD=deoxycytidine kinase /DB_XREF=gi:4503268 /UG=Hs.709 deoxycytidine kinase /FL=gb:M60527.1 gb:NM_000788.1 NM_000788 deoxycytidine kinase DCK 1633 NM_000788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded /// 0042803 // protein homodimerization activity // inferred from physical interaction 203303_at NM_006520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006520.1 /DEF=Homo sapiens t-complex-associated-testis-expressed 1-like (TCTE1L), mRNA. /FEA=mRNA /GEN=TCTE1L /PROD=t-complex-associated-testis-expressed 1-like /DB_XREF=gi:5730086 /UG=Hs.75307 t-complex-associated-testis-expressed 1-like /FL=gb:BC000968.2 gb:U02556.1 gb:NM_006520.1 NM_006520 dynein, light chain, Tctex-type 3 DYNLT3 6990 NM_006520 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203304_at NM_012342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012342.1 /DEF=Homo sapiens putative transmembrane protein (NMA), mRNA. /FEA=mRNA /GEN=NMA /PROD=putative transmembrane protein /DB_XREF=gi:6912533 /UG=Hs.78776 putative transmembrane protein /FL=gb:U23070.1 gb:NM_012342.1 NM_012342 BMP and activin membrane-bound inhibitor BAMBI 25805 NM_012342 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016477 // cell migration // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // traceable author statement 203305_at NM_000129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000129.2 /DEF=Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA. /FEA=mRNA /GEN=F13A1 /PROD=coagulation factor XIII A1 subunit precursor /DB_XREF=gi:9961355 /UG=Hs.80424 coagulation factor XIII, A1 polypeptide /FL=gb:M14354.1 gb:NM_000129.2 NM_000129 coagulation factor XIII, A1 polypeptide F13A1 2162 NM_000129 /// XM_006715010 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203306_s_at NM_006416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006416.1 /DEF=Homo sapiens solute carrier family 35 (CMP-sialic acid transporter), member 1 (SLC35A1), mRNA. /FEA=mRNA /GEN=SLC35A1 /PROD=solute carrier family 35 (CMP-sialic acidtransporter), member 1 /DB_XREF=gi:5453620 /UG=Hs.82921 solute carrier family 35 (CMP-sialic acid transporter), member 1 /FL=gb:D87969.1 gb:NM_006416.1 NM_006416 solute carrier family 35 (CMP-sialic acid transporter), member A1 SLC35A1 10559 NM_001168398 /// NM_006416 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015782 // CMP-N-acetylneuraminate transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005456 // CMP-N-acetylneuraminate transmembrane transporter activity // traceable author statement 203307_at NM_005275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005275.1 /DEF=Homo sapiens guanine nucleotide binding protein-like 1 (GNL1), mRNA. /FEA=mRNA /GEN=GNL1 /PROD=guanine nucleotide binding protein-like 1 /DB_XREF=gi:4885288 /UG=Hs.83147 guanine nucleotide binding protein-like 1 /FL=gb:NM_005275.1 gb:L25665.1 NM_005275 guanine nucleotide binding protein-like 1 GNL1 2794 NM_005275 /// XM_005249015 /// XM_005272793 /// XM_005274939 /// XM_005275093 /// XM_005275235 /// XM_005275369 /// XM_005275529 0002456 // T cell mediated immunity // non-traceable author statement /// 0006184 // GTP catabolic process // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0042254 // ribosome biogenesis // not recorded 0005615 // extracellular space // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005525 // GTP binding // non-traceable author statement 203308_x_at AI185798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI185798 /FEA=EST /DB_XREF=gi:3736436 /DB_XREF=est:qe49f04.x1 /CLONE=IMAGE:1742335 /UG=Hs.83951 Hermansky-Pudlak syndrome /FL=gb:U65676.1 gb:NM_000195.1 AI185798 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 203309_s_at NM_000195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000195.1 /DEF=Homo sapiens Hermansky-Pudlak syndrome (HPS), mRNA. /FEA=mRNA /GEN=HPS /PROD=Hermansky-Pudlak syndrome protein /DB_XREF=gi:4504484 /UG=Hs.83951 Hermansky-Pudlak syndrome /FL=gb:U65676.1 gb:NM_000195.1 NM_000195 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 203310_at NM_007269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007269.1 /DEF=Homo sapiens syntaxin binding protein 3 (STXBP3), mRNA. /FEA=mRNA /GEN=STXBP3 /PROD=syntaxin 4 binding protein /DB_XREF=gi:6005885 /UG=Hs.8813 syntaxin binding protein 3 /FL=gb:D63506.1 gb:AF032922.1 gb:NM_007269.1 NM_007269 syntaxin binding protein 3 STXBP3 6814 NM_007269 0006810 // transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043312 // neutrophil degranulation // inferred from expression pattern /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from mutant phenotype /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031091 // platelet alpha granule // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070820 // tertiary granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction 203311_s_at M57763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57763.1 /DEF=Human ADP-ribosylation factor (hARF6) mRNA, complete cds. /FEA=mRNA /GEN=hARF6 /PROD=ADP-ribosylation factor /DB_XREF=gi:178988 /UG=Hs.89474 ADP-ribosylation factor 6 /FL=gb:BC002952.1 gb:M57763.1 gb:NM_001663.2 M57763 ADP-ribosylation factor 6 ARF6 382 NM_001663 0001889 // liver development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // inferred from direct assay /// 0033028 // myeloid cell apoptotic process // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction 203312_x_at NM_001663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001663.2 /DEF=Homo sapiens ADP-ribosylation factor 6 (ARF6), mRNA. /FEA=mRNA /GEN=ARF6 /PROD=ADP-ribosylation factor 6 /DB_XREF=gi:6996000 /UG=Hs.89474 ADP-ribosylation factor 6 /FL=gb:BC002952.1 gb:M57763.1 gb:NM_001663.2 NM_001663 ADP-ribosylation factor 6 ARF6 382 NM_001663 0001889 // liver development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // inferred from direct assay /// 0033028 // myeloid cell apoptotic process // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction 203313_s_at NM_003244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003244.1 /DEF=Homo sapiens TG-interacting factor (TALE family homeobox) (TGIF), mRNA. /FEA=mRNA /GEN=TGIF /PROD=TG-interacting factor (TALE family homeobox) /DB_XREF=gi:4507472 /UG=Hs.90077 TG-interacting factor (TALE family homeobox) /FL=gb:BC000814.1 gb:NM_003244.1 gb:AF179900.1 NM_003244 TGFB-induced factor homeobox 1 TGIF1 7050 NM_001278682 /// NM_001278684 /// NM_001278686 /// NM_003244 /// NM_170695 /// NM_173207 /// NM_173208 /// NM_173209 /// NM_173210 /// NM_173211 /// NM_174886 /// XM_005258135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0038092 // nodal signaling pathway // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from electronic annotation 203314_at NM_012227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012227.1 /DEF=Homo sapiens Pseudoautosomal GTP-binding protein-like (PGPL), mRNA. /FEA=mRNA /GEN=PGPL /PROD=Pseudoautosomal GTP-binding protein-likeprotein /DB_XREF=gi:6912587 /UG=Hs.101033 Pseudoautosomal GTP-binding protein-like /FL=gb:NM_012227.1 NM_012227 GTP binding protein 6 (putative) GTPBP6 8225 NM_012227 /// XM_006724447 /// XM_006724868 0015684 // ferrous iron transport // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203315_at BC000103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000103.1 /DEF=Homo sapiens, NCK adaptor protein 2, clone MGC:1698, mRNA, complete cds. /FEA=mRNA /PROD=NCK adaptor protein 2 /DB_XREF=gi:12652708 /UG=Hs.101695 NCK adaptor protein 2 /FL=gb:BC000103.1 gb:AF043119.1 gb:AF047487.1 gb:NM_003581.1 BC000103 NCK adaptor protein 2 NCK2 8440 NM_001004720 /// NM_001004722 /// NM_003581 /// XM_006712797 /// XM_006712798 0006417 // regulation of translation // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042110 // T cell activation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019887 // protein kinase regulator activity // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 203316_s_at NM_003094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003094.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide E (SNRPE), mRNA. /FEA=mRNA /GEN=SNRPE /PROD=small nuclear ribonucleoprotein polypeptide E /DB_XREF=gi:4507128 /UG=Hs.1066 small nuclear ribonucleoprotein polypeptide E /FL=gb:BC002639.1 gb:M37716.1 gb:NM_003094.1 NM_003094 small nuclear ribonucleoprotein polypeptide E SNRPE 6635 NM_003094 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0042633 // hair cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // non-traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203317_at NM_012455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012455.1 /DEF=Homo sapiens SEC7 homolog (TIC), mRNA. /FEA=mRNA /GEN=TIC /PROD=SEC7 homolog /DB_XREF=gi:6912705 /UG=Hs.110121 SEC7 homolog /FL=gb:U63127.1 gb:NM_012455.1 NM_012455 pleckstrin and Sec7 domain containing 4 PSD4 23550 NM_012455 /// XM_005263634 /// XM_006712392 /// XM_006712393 /// XM_006712394 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203318_s_at NM_021964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021964.1 /DEF=Homo sapiens zinc finger protein 148 (pHZ-52) (ZNF148), mRNA. /FEA=mRNA /GEN=ZNF148 /PROD=zinc finger protein 148 (pHZ-52) /DB_XREF=gi:11415035 /UG=Hs.112180 zinc finger protein 148 (pHZ-52) /FL=gb:NM_021964.1 gb:L04282.1 NM_021964 zinc finger protein 148 ZNF148 7707 NM_021964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007276 // gamete generation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203319_s_at L04282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L04282.1 /DEF=Human CACCC box-binding protein mRNA, complete cds. /FEA=mRNA /PROD=CACCC box-binding protein /DB_XREF=gi:388318 /UG=Hs.112180 zinc finger protein 148 (pHZ-52) /FL=gb:NM_021964.1 gb:L04282.1 L04282 zinc finger protein 148 ZNF148 7707 NM_021964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007276 // gamete generation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203320_at NM_005475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005475.1 /DEF=Homo sapiens lymphocyte adaptor protein (LNK), mRNA. /FEA=mRNA /GEN=LNK /PROD=lymphocyte adaptor protein /DB_XREF=gi:4885454 /UG=Hs.13131 lymphocyte adaptor protein /FL=gb:AF055581.1 gb:NM_005475.1 NM_005475 SH2B adaptor protein 3 SH2B3 10019 NM_001291424 /// NM_005475 /// XM_005253818 /// XM_005253819 /// XM_006719180 0007596 // blood coagulation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from electronic annotation 203321_s_at AK022688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022688.1 /DEF=Homo sapiens cDNA FLJ12626 fis, clone NT2RM4001810, weakly similar to AGGRECAN CORE PROTEIN PRECURSOR. /FEA=CDS /DB_XREF=gi:10434228 /UG=Hs.131915 KIAA0863 protein /FL=gb:AB020670.1 gb:NM_014913.1 AK022688 ADNP homeobox 2 ADNP2 22850 NM_014913 /// XM_005266656 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203322_at AU145934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145934 /FEA=EST /DB_XREF=gi:11007455 /DB_XREF=est:AU145934 /CLONE=HEMBA1006312 /UG=Hs.131915 KIAA0863 protein /FL=gb:AB020670.1 gb:NM_014913.1 AU145934 ADNP homeobox 2 ADNP2 22850 NM_014913 /// XM_005266656 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203323_at BF197655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF197655 /FEA=EST /DB_XREF=gi:11086950 /DB_XREF=est:7m95b04.x1 /CLONE=IMAGE:3562710 /UG=Hs.139851 caveolin 2 /FL=gb:BC005256.1 gb:AF035752.1 gb:NM_001233.1 BF197655 caveolin 2 CAV2 858 NM_001206747 /// NM_001206748 /// NM_001233 /// NM_198212 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from expression pattern /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0070836 // caveola assembly // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from electronic annotation 203324_s_at NM_001233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001233.1 /DEF=Homo sapiens caveolin 2 (CAV2), mRNA. /FEA=mRNA /GEN=CAV2 /PROD=caveolin 2 /DB_XREF=gi:4557412 /UG=Hs.139851 caveolin 2 /FL=gb:BC005256.1 gb:AF035752.1 gb:NM_001233.1 NM_001233 caveolin 2 CAV2 858 NM_001206747 /// NM_001206748 /// NM_001233 /// NM_198212 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from expression pattern /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0070836 // caveola assembly // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from electronic annotation 203325_s_at AI130969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI130969 /FEA=EST /DB_XREF=gi:3600985 /DB_XREF=est:qc15e01.x1 /CLONE=IMAGE:1709688 /UG=Hs.146428 collagen, type V, alpha 1 /FL=gb:M76729.1 gb:D90279.1 gb:NM_000093.1 AI130969 collagen, type V, alpha 1 COL5A1 1289 NM_000093 /// NM_001278074 0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 203326_x_at M76729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76729.1 /DEF=Human pro-alpha-1 (V) collagen mRNA, complete cds. /FEA=mRNA /GEN=COL5A1 /PROD=pro-alpha-1 type V collagen /DB_XREF=gi:189519 /UG=Hs.146428 collagen, type V, alpha 1 /FL=gb:M76729.1 gb:D90279.1 gb:NM_000093.1 M76729 0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005588 // collagen type V trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 203327_at N22903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N22903 /FEA=EST /DB_XREF=gi:1137053 /DB_XREF=est:yx66e04.s1 /CLONE=IMAGE:266718 /UG=Hs.1508 insulin-degrading enzyme /FL=gb:M21188.1 gb:NM_004969.1 N22903 insulin-degrading enzyme IDE 3416 NM_001165946 /// NM_004969 /// XM_005269766 /// XM_005269769 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0008340 // determination of adult lifespan // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010992 // ubiquitin homeostasis // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 1901142 // insulin metabolic process // inferred from direct assay /// 1901143 // insulin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031626 // beta-endorphin binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203328_x_at NM_004969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004969.1 /DEF=Homo sapiens insulin-degrading enzyme (IDE), mRNA. /FEA=mRNA /GEN=IDE /PROD=insulysin /DB_XREF=gi:4826769 /UG=Hs.1508 insulin-degrading enzyme /FL=gb:M21188.1 gb:NM_004969.1 NM_004969 insulin-degrading enzyme IDE 3416 NM_001165946 /// NM_004969 /// XM_005269766 /// XM_005269769 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0008340 // determination of adult lifespan // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010992 // ubiquitin homeostasis // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 1901142 // insulin metabolic process // inferred from direct assay /// 1901143 // insulin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031626 // beta-endorphin binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203329_at NM_002845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002845.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, M (PTPRM), mRNA. /FEA=mRNA /GEN=PTPRM /PROD=protein tyrosine phosphatase, receptor type, mupolypeptide /DB_XREF=gi:4506318 /UG=Hs.154151 protein tyrosine phosphatase, receptor type, M /FL=gb:NM_002845.1 NM_002845 protein tyrosine phosphatase, receptor type, M PTPRM 5797 NM_001105244 /// NM_002845 /// XM_006722335 /// XM_006722336 /// XM_006722337 /// XM_006722338 /// XR_430046 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010842 // retina layer formation // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0031290 // retinal ganglion cell axon guidance // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay 203330_s_at NM_003164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003164.1 /DEF=Homo sapiens syntaxin 5A (STX5A), mRNA. /FEA=mRNA /GEN=STX5A /PROD=syntaxin 5A /DB_XREF=gi:4507292 /UG=Hs.154546 syntaxin 5A /FL=gb:NM_003164.1 gb:U26648.1 NM_003164 syntaxin 5 STX5 6811 NM_001244666 /// NM_003164 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006903 // vesicle targeting // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 203331_s_at U53470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U53470.1 /DEF=Human signaling inositol polyphosphate phosphatase SHIP II mRNA, complete cds. /FEA=mRNA /PROD=signaling inositol polyphosphate phosphataseSHIP II /DB_XREF=gi:4097284 /UG=Hs.155939 inositol polyphosphate-5-phosphatase, 145kD /FL=gb:U50040.1 gb:U57650.1 gb:U84400.1 gb:U53470.1 gb:NM_005541.1 U53470 inositol polyphosphate-5-phosphatase, 145kDa INPP5D 3635 NM_001017915 /// NM_005541 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045656 // negative regulation of monocyte differentiation // inferred from electronic annotation /// 0045659 // negative regulation of neutrophil differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from electronic annotation 203332_s_at NM_005541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005541.1 /DEF=Homo sapiens inositol polyphosphate-5-phosphatase, 145kD (INPP5D), mRNA. /FEA=mRNA /GEN=INPP5D /PROD=inositol polyphosphate-5-phosphatase, 145kD /DB_XREF=gi:5031798 /UG=Hs.155939 inositol polyphosphate-5-phosphatase, 145kD /FL=gb:U50040.1 gb:U57650.1 gb:U84400.1 gb:U53470.1 gb:NM_005541.1 NM_005541 inositol polyphosphate-5-phosphatase, 145kDa INPP5D 3635 NM_001017915 /// NM_005541 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045656 // negative regulation of monocyte differentiation // inferred from electronic annotation /// 0045659 // negative regulation of neutrophil differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from electronic annotation 203333_at NM_014970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014970.1 /DEF=Homo sapiens smg GDS-ASSOCIATED PROTEIN (SMAP), mRNA. /FEA=mRNA /GEN=SMAP /PROD=smg GDS-ASSOCIATED PROTEIN /DB_XREF=gi:7657592 /UG=Hs.171374 smg GDS-ASSOCIATED PROTEIN /FL=gb:U59919.1 gb:NM_014970.1 NM_014970 kinesin-associated protein 3 KIFAP3 22920 NM_001204514 /// NM_001204516 /// NM_001204517 /// NM_014970 /// XM_005244970 0006461 // protein complex assembly // traceable author statement /// 0007017 // microtubule-based process // inferred from sequence or structural similarity /// 0007018 // microtubule-based movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0046587 // positive regulation of calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072383 // plus-end-directed vesicle transport along microtubule // traceable author statement 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016939 // kinesin II complex // inferred from direct assay /// 0016939 // kinesin II complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction 203334_at NM_004941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004941.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 (RNA helicase) (DDX8), mRNA. /FEA=mRNA /GEN=DDX8 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 /DB_XREF=gi:4826689 /UG=Hs.171872 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 (RNA helicase) /FL=gb:D50487.1 gb:NM_004941.1 NM_004941 DEAH (Asp-Glu-Ala-His) box polypeptide 8 DHX8 1659 NM_004941 /// XM_005257113 /// XM_005257114 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203335_at NM_006214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006214.1 /DEF=Homo sapiens phytanoyl-CoA hydroxylase (Refsum disease) (PHYH), mRNA. /FEA=mRNA /GEN=PHYH /PROD=phytanoyl-CoA hydroxylase (Refsum disease) /DB_XREF=gi:5453883 /UG=Hs.172887 phytanoyl-CoA hydroxylase (Refsum disease) /FL=gb:AF023462.1 gb:AF112977.1 gb:NM_006214.1 NM_006214 phytanoyl-CoA 2-hydroxylase PHYH 5264 NM_001037537 /// NM_006214 /// XM_005252469 0001561 // fatty acid alpha-oxidation // inferred from direct assay /// 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097089 // methyl-branched fatty acid metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay /// 0048244 // phytanoyl-CoA dioxygenase activity // inferred from direct assay /// 0048244 // phytanoyl-CoA dioxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 203336_s_at AL548363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL548363 /FEA=EST /DB_XREF=gi:12883296 /DB_XREF=est:AL548363 /CLONE=CS0DI016YO13 (5 prime) /UG=Hs.173274 integrin cytoplasmic domain-associated protein 1 /FL=gb:AF012023.1 gb:NM_004763.1 AL548363 integrin beta 1 binding protein 1 ITGB1BP1 9270 NM_004763 /// NM_022334 /// XM_005246183 /// XM_005246184 /// XM_005246185 /// XM_005246186 /// XM_005246187 /// XM_005246188 /// XM_005246189 /// XM_006711903 0001525 // angiogenesis // inferred from electronic annotation /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010764 // negative regulation of fibroblast migration // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0016477 // cell migration // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035148 // tube formation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203337_x_at NM_004763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004763.1 /DEF=Homo sapiens integrin cytoplasmic domain-associated protein 1 (ICAP-1A), transcript variant 1, mRNA. /FEA=mRNA /GEN=ICAP-1A /PROD=integrin cytoplasmic domain-associated protein1, isoform 1 /DB_XREF=gi:4758577 /UG=Hs.173274 integrin cytoplasmic domain-associated protein 1 /FL=gb:AF012023.1 gb:NM_004763.1 NM_004763 integrin beta 1 binding protein 1 ITGB1BP1 9270 NM_004763 /// NM_022334 /// XM_005246183 /// XM_005246184 /// XM_005246185 /// XM_005246186 /// XM_005246187 /// XM_005246188 /// XM_005246189 /// XM_006711903 0001525 // angiogenesis // inferred from electronic annotation /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010764 // negative regulation of fibroblast migration // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0016477 // cell migration // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035148 // tube formation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203338_at NM_006246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006246.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (PPP2R5E), mRNA. /FEA=mRNA /GEN=PPP2R5E /PROD=protein phosphatase 2, regulatory subunit B(B56), epsilon isoform /DB_XREF=gi:5453955 /UG=Hs.173328 protein phosphatase 2, regulatory subunit B (B56), epsilon isoform /FL=gb:L76703.1 gb:NM_006246.1 NM_006246 protein phosphatase 2, regulatory subunit B', epsilon isoform PPP2R5E 5529 NM_001282179 /// NM_001282180 /// NM_001282181 /// NM_001282182 /// NM_006246 /// NR_104104 0007165 // signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 203339_at AI887457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI887457 /FEA=EST /DB_XREF=gi:5592621 /DB_XREF=est:wm05f07.x1 /CLONE=IMAGE:2435077 /UG=Hs.179866 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 /FL=gb:NM_003705.1 AI887457 solute carrier family 25 (aspartate/glutamate carrier), member 12 SLC25A12 8604 NM_003705 /// NR_047549 /// XM_005246923 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203340_s_at NM_003705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003705.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier, Aralar), member 12 (SLC25A12), mRNA. /FEA=mRNA /GEN=SLC25A12 /PROD=solute carrier family 25 (mitochondrial carrier,Aralar), member 12 /DB_XREF=gi:4507006 /UG=Hs.179866 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 /FL=gb:NM_003705.1 NM_003705 solute carrier family 25 (aspartate/glutamate carrier), member 12 SLC25A12 8604 NM_003705 /// NR_047549 /// XM_005246923 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203341_at NM_005760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005760.1 /DEF=Homo sapiens CCAAT-box-binding transcription factor (CBF2), mRNA. /FEA=mRNA /GEN=CBF2 /PROD=CCAAT-box-binding transcription factor /DB_XREF=gi:5031624 /UG=Hs.184760 CCAAT-box-binding transcription factor /FL=gb:M37197.1 gb:NM_005760.1 NM_005760 CCAAT/enhancer binding protein (C/EBP), zeta CEBPZ 10153 NM_005760 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203342_at NM_005834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005834.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 17 (yeast) homolog B (TIM17B), mRNA. /FEA=mRNA /GEN=TIM17B /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog B /DB_XREF=gi:5032180 /UG=Hs.19105 translocase of inner mitochondrial membrane 17 (yeast) homolog B /FL=gb:AJ005895.1 gb:AF034790.1 gb:AF077039.1 gb:NM_005834.1 NM_005834 translocase of inner mitochondrial membrane 17 homolog B (yeast) TIMM17B 10245 NM_001167947 /// NM_005834 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203343_at NM_003359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003359.1 /DEF=Homo sapiens UDP-glucose dehydrogenase (UGDH), mRNA. /FEA=mRNA /GEN=UGDH /PROD=UDP-glucose dehydrogenase /DB_XREF=gi:4507812 /UG=Hs.28309 UDP-glucose dehydrogenase /FL=gb:AF061016.1 gb:NM_003359.1 NM_003359 UDP-glucose 6-dehydrogenase UGDH 7358 NM_001184700 /// NM_001184701 /// NM_003359 /// XM_005262667 /// XM_006714029 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006011 // UDP-glucose metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006065 // UDP-glucuronate biosynthetic process // inferred from electronic annotation /// 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0052695 // cellular glucuronidation // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003979 // UDP-glucose 6-dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 203344_s_at NM_002894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002894.1 /DEF=Homo sapiens retinoblastoma-binding protein 8 (RBBP8), mRNA. /FEA=mRNA /GEN=RBBP8 /PROD=retinoblastoma-binding protein 8 /DB_XREF=gi:4506440 /UG=Hs.29287 retinoblastoma-binding protein 8 /FL=gb:AF043431.1 gb:NM_002894.1 NM_002894 retinoblastoma binding protein 8 RBBP8 5932 NM_002894 /// NM_203291 /// NM_203292 /// XM_005258325 /// XM_005258326 /// XM_006722519 /// XM_006722520 /// XM_006722521 /// XM_006722522 0000075 // cell cycle checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0010792 // DNA double-strand break processing involved in repair via single-strand annealing // inferred from mutant phenotype /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from mutant phenotype /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203345_s_at AI566096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI566096 /FEA=EST /DB_XREF=gi:4524548 /DB_XREF=est:tn53d02.x1 /CLONE=IMAGE:2172099 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1 AI566096 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203346_s_at AF072814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072814.1 /DEF=Homo sapiens PHD finger DNA binding protein isoform 1 (M96) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=M96 /PROD=PHD finger DNA binding protein isoform 1 /DB_XREF=gi:3342451 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1 AF072814 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203347_s_at NM_007358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007358.1 /DEF=Homo sapiens putative DNA binding protein (M96), mRNA. /FEA=mRNA /GEN=M96 /PROD=putative DNA binding protein /DB_XREF=gi:6678763 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1 NM_007358 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203348_s_at BF060791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF060791 /FEA=EST /DB_XREF=gi:10819701 /DB_XREF=est:7j60g07.x1 /CLONE=IMAGE:3390876 /UG=Hs.43697 ets variant gene 5 (ets-related molecule) /FL=gb:NM_004454.1 BF060791 ets variant 5 ETV5 2119 NM_004454 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203349_s_at NM_004454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004454.1 /DEF=Homo sapiens ets variant gene 5 (ets-related molecule) (ETV5), mRNA. /FEA=mRNA /GEN=ETV5 /PROD=ets variant gene 5 (ets-related molecule) /DB_XREF=gi:4758315 /UG=Hs.43697 ets variant gene 5 (ets-related molecule) /FL=gb:NM_004454.1 NM_004454 ets variant 5 ETV5 2119 NM_004454 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203350_at NM_001128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001128.1 /DEF=Homo sapiens adaptor-related protein complex 1, gamma 1 subunit (AP1G1), mRNA. /FEA=mRNA /GEN=AP1G1 /PROD=adaptor-related protein complex 1, gamma 1subunit /DB_XREF=gi:4501978 /UG=Hs.5344 adaptor-related protein complex 1, gamma 1 subunit /FL=gb:AB015317.1 gb:NM_001128.1 NM_001128 adaptor-related protein complex 1, gamma 1 subunit AP1G1 164 NM_001030007 /// NM_001128 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032438 // melanosome organization // inferred by curator /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203351_s_at AF047598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047598.1 /DEF=Homo sapiens origin recognition complex subunit 4 (ORC4L) mRNA, complete cds. /FEA=mRNA /GEN=ORC4L /PROD=origin recognition complex subunit 4 /DB_XREF=gi:2906225 /UG=Hs.55055 origin recognition complex, subunit 4 (yeast homolog)-like /FL=gb:BC005388.1 gb:AF022108.1 gb:AF047598.1 gb:NM_002552.1 gb:AF132596.1 AF047598 origin recognition complex, subunit 4 ORC4 5000 NM_001190879 /// NM_001190881 /// NM_001190882 /// NM_002552 /// NM_181741 /// NM_181742 /// XM_006712556 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from mutant phenotype 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203352_at NM_002552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002552.1 /DEF=Homo sapiens origin recognition complex, subunit 4 (yeast homolog)-like (ORC4L), mRNA. /FEA=mRNA /GEN=ORC4L /PROD=origin recognition complex, subunit 4 (yeasthomolog)-like /DB_XREF=gi:4505522 /UG=Hs.55055 origin recognition complex, subunit 4 (yeast homolog)-like /FL=gb:BC005388.1 gb:AF022108.1 gb:AF047598.1 gb:NM_002552.1 gb:AF132596.1 NM_002552 origin recognition complex, subunit 4 ORC4 5000 NM_001190879 /// NM_001190881 /// NM_001190882 /// NM_002552 /// NM_181741 /// NM_181742 /// XM_006712556 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from mutant phenotype 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203353_s_at NM_015846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015846.1 /DEF=Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 1, mRNA. /FEA=mRNA /GEN=MBD1 /PROD=methyl-CpG binding domain protein 1, isoform 1 /DB_XREF=gi:7710138 /UG=Hs.6211 methyl-CpG binding domain protein 1 /FL=gb:AF078830.1 gb:NM_015846.1 NM_015846 methyl-CpG binding domain protein 1 MBD1 4152 NM_001204136 /// NM_001204137 /// NM_001204138 /// NM_001204139 /// NM_001204140 /// NM_001204141 /// NM_001204142 /// NM_001204143 /// NM_001204151 /// NM_002384 /// NM_015844 /// NM_015845 /// NM_015846 /// NM_015847 /// XM_005258262 /// XM_005258264 /// XM_005258265 /// XM_005258268 /// XM_005258271 /// XM_005258272 /// XM_005258274 /// XM_006722452 /// XM_006722453 /// XM_006722454 /// XM_006722455 /// XM_006722456 /// XM_006722457 /// XM_006722458 /// XM_006722459 /// XM_006722460 /// XM_006722461 /// XM_006722462 /// XM_006722463 /// XM_006722464 /// XM_006722465 /// XM_006722466 /// XM_006722467 /// XM_006722468 /// XM_006722469 /// XM_006722470 /// XM_006722471 /// XM_006722472 /// XM_006722473 /// XM_006722474 /// XM_006722475 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203354_s_at AW117368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW117368 /FEA=EST /DB_XREF=gi:6085952 /DB_XREF=est:xd88h01.x1 /CLONE=IMAGE:2604721 /UG=Hs.6763 KIAA0942 protein /FL=gb:AF243495.2 gb:NM_015310.1 AW117368 pleckstrin and Sec7 domain containing 3 PSD3 23362 NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation 203355_s_at NM_015310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015310.1 /DEF=Homo sapiens KIAA0942 protein (KIAA0942), mRNA. /FEA=mRNA /GEN=KIAA0942 /PROD=KIAA0942 protein /DB_XREF=gi:7662395 /UG=Hs.6763 KIAA0942 protein /FL=gb:AF243495.2 gb:NM_015310.1 NM_015310 pleckstrin and Sec7 domain containing 3 PSD3 23362 NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation 203356_at BE349584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE349584 /FEA=EST /DB_XREF=gi:9261437 /DB_XREF=est:ht55h12.x1 /CLONE=IMAGE:3150695 /UG=Hs.7145 calpain 7 /FL=gb:AB028639.1 gb:NM_014296.1 BE349584 calpain 7 CAPN7 23473 NM_014296 /// XM_005265008 /// XM_006713080 /// XR_245107 /// XR_245108 0006508 // proteolysis // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0090541 // MIT domain binding // inferred from physical interaction 203357_s_at NM_014296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014296.1 /DEF=Homo sapiens calpain 7 (CAPN7), mRNA. /FEA=mRNA /GEN=CAPN7 /PROD=calpain 7 /DB_XREF=gi:7656958 /UG=Hs.7145 calpain 7 /FL=gb:AB028639.1 gb:NM_014296.1 NM_014296 calpain 7 CAPN7 23473 NM_014296 /// XM_005265008 /// XM_006713080 /// XR_245107 /// XR_245108 0006508 // proteolysis // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0090541 // MIT domain binding // inferred from physical interaction 203358_s_at NM_004456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004456.1 /DEF=Homo sapiens enhancer of zeste (Drosophila) homolog 2 (EZH2), mRNA. /FEA=mRNA /GEN=EZH2 /PROD=enhancer of zeste (Drosophila) homolog 2 /DB_XREF=gi:4758323 /UG=Hs.77256 enhancer of zeste (Drosophila) homolog 2 /FL=gb:U61145.1 gb:NM_004456.1 NM_004456 enhancer of zeste 2 polycomb repressive complex 2 subunit EZH2 2146 NM_001203247 /// NM_001203248 /// NM_001203249 /// NM_004456 /// NM_152998 /// XM_005249962 /// XM_005249963 /// XM_005249964 /// XM_006715883 /// XM_006715884 /// XM_006715885 /// XM_006715886 /// XM_006715887 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014013 // regulation of gliogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045605 // negative regulation of epidermal cell differentiation // inferred from electronic annotation /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // traceable author statement 203359_s_at AL525412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL525412 /FEA=EST /DB_XREF=gi:12788905 /DB_XREF=est:AL525412 /CLONE=CS0DC011YJ12 (5 prime) /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2 AL525412 GJA9-MYCBP readthrough /// MYC binding protein GJA9-MYCBP /// MYCBP 26292 /// 100527950 NM_012333 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203360_s_at D50692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50692.1 /DEF=Homo sapiens mRNA for c-myc binding protein, complete cds. /FEA=mRNA /PROD=c-myc binding protein /DB_XREF=gi:1785850 /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2 D50692 gap junction protein, alpha 9, 59kDa /// GJA9-MYCBP readthrough /// MYC binding protein GJA9 /// GJA9-MYCBP /// MYCBP 26292 /// 81025 /// 100527950 NM_012333 /// NM_030772 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203361_s_at NM_012333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012333.2 /DEF=Homo sapiens c-myc binding protein (MYCBP), mRNA. /FEA=mRNA /GEN=MYCBP /PROD=c-myc binding protein /DB_XREF=gi:8850230 /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2 NM_012333 GJA9-MYCBP readthrough /// MYC binding protein GJA9-MYCBP /// MYCBP 26292 /// 100527950 NM_012333 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203362_s_at NM_002358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002358.2 /DEF=Homo sapiens MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 (MAD2L1), mRNA. /FEA=mRNA /GEN=MAD2L1 /PROD=MAD2-like 1 /DB_XREF=gi:6466452 /UG=Hs.79078 MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 /FL=gb:BC000356.1 gb:U65410.1 gb:NM_002358.2 gb:U31278.1 NM_002358 MAD2 mitotic arrest deficient-like 1 (yeast) MAD2L1 4085 NM_002358 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0060564 // negative regulation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203363_s_at AU153525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153525 /FEA=EST /DB_XREF=gi:11015046 /DB_XREF=est:AU153525 /CLONE=NT2RP3003369 /UG=Hs.79672 KIAA0652 gene product /FL=gb:AB014552.1 gb:NM_014741.1 AU153525 autophagy related 13 ATG13 9776 NM_001142673 /// NM_001205119 /// NM_001205120 /// NM_001205121 /// NM_001205122 /// NM_014741 /// XM_005253262 /// XM_005253263 /// XM_005253265 /// XM_005253266 /// XM_005253268 /// XM_006718394 /// XM_006718395 /// XM_006718396 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0034273 // Atg1p signaling complex // /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 203364_s_at NM_014741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014741.1 /DEF=Homo sapiens KIAA0652 gene product (KIAA0652), mRNA. /FEA=mRNA /GEN=KIAA0652 /PROD=KIAA0652 gene product /DB_XREF=gi:7662225 /UG=Hs.79672 KIAA0652 gene product /FL=gb:AB014552.1 gb:NM_014741.1 NM_014741 autophagy related 13 ATG13 9776 NM_001142673 /// NM_001205119 /// NM_001205120 /// NM_001205121 /// NM_001205122 /// NM_014741 /// XM_005253262 /// XM_005253263 /// XM_005253265 /// XM_005253266 /// XM_005253268 /// XM_006718394 /// XM_006718395 /// XM_006718396 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0034273 // Atg1p signaling complex // /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 203365_s_at NM_002428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002428.1 /DEF=Homo sapiens matrix metalloproteinase 15 (membrane-inserted) (MMP15), mRNA. /FEA=mRNA /GEN=MMP15 /PROD=matrix metalloproteinase 15 preproprotein /DB_XREF=gi:4505210 /UG=Hs.80343 matrix metalloproteinase 15 (membrane-inserted) /FL=gb:D86331.1 gb:NM_002428.1 NM_002428 matrix metallopeptidase 15 (membrane-inserted) MMP15 4324 NM_002428 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203366_at NM_002693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002693.1 /DEF=Homo sapiens polymerase (DNA directed), gamma (POLG), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=POLG /PROD=polymerase (DNA directed), gamma /DB_XREF=gi:4505936 /UG=Hs.80961 polymerase (DNA directed), gamma /FL=gb:U60325.1 gb:D84103.1 gb:NM_002693.1 NM_002693 polymerase (DNA directed), gamma POLG 5428 NM_001126131 /// NM_002693 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 203367_at NM_007026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007026.1 /DEF=Homo sapiens MKP-1 like protein tyrosine phosphatase (MKP-L), mRNA. /FEA=mRNA /GEN=MKP-L /PROD=MKP-1 like protein tyrosine phosphatase /DB_XREF=gi:5902001 /UG=Hs.91448 MKP-1 like protein tyrosine phosphatase /FL=gb:BC000370.1 gb:BC001894.1 gb:BC004448.1 gb:AF038844.1 gb:NM_007026.1 gb:AF120032.1 NM_007026 dual specificity phosphatase 14 DUSP14 11072 NM_007026 /// XM_005256977 /// XM_006725300 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203368_at NM_015513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015513.1 /DEF=Homo sapiens DKFZP566D213 protein (DKFZP566D213), mRNA. /FEA=mRNA /GEN=DKFZP566D213 /PROD=DKFZP566D213 protein /DB_XREF=gi:7661643 /UG=Hs.9383 DKFZP566D213 protein /FL=gb:AL050275.1 gb:NM_015513.1 NM_015513 cysteine-rich with EGF-like domains 1 CRELD1 78987 NM_001031717 /// NM_001077415 /// NM_015513 /// XM_006713328 /// XM_006713329 /// XM_006713330 /// XM_006713331 /// XR_427293 /// XR_427294 0003197 // endocardial cushion development // traceable author statement /// 0003279 // cardiac septum development // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203369_x_at AI825846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825846 /FEA=EST /DB_XREF=gi:5446517 /DB_XREF=est:td19c09.x1 /CLONE=IMAGE:2076112 /UG=Hs.102948 enigma (LIM domain protein) /FL=gb:NM_005451.2 gb:BC001093.1 gb:AF265209.1 AI825846 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203370_s_at NM_005451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005451.2 /DEF=Homo sapiens enigma (LIM domain protein) (ENIGMA), mRNA. /FEA=mRNA /GEN=ENIGMA /PROD=enigma protein /DB_XREF=gi:11496884 /UG=Hs.102948 enigma (LIM domain protein) /FL=gb:NM_005451.2 gb:BC001093.1 gb:AF265209.1 NM_005451 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203371_s_at NM_002491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002491.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) (NDUFB3), mRNA. /FEA=mRNA /GEN=NDUFB3 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 3 (12kD, B12) /DB_XREF=gi:4505360 /UG=Hs.109760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) /FL=gb:AF047183.1 gb:NM_002491.1 NM_002491 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa NDUFB3 4709 NM_001257102 /// NM_002491 /// XM_006712544 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203372_s_at AB004903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB004903.1 /DEF=Homo sapiens mRNA for STAT induced STAT inhibitor-2, complete cds. /FEA=mRNA /PROD=STAT induced STAT inhibitor-2 /DB_XREF=gi:2443360 /UG=Hs.110776 STAT induced STAT inhibitor-2 /FL=gb:AB004903.1 gb:AB006966.1 gb:AF037989.1 gb:AF020590.1 gb:NM_003877.1 AB004903 suppressor of cytokine signaling 2 SOCS2 8835 NM_001270467 /// NM_001270468 /// NM_001270469 /// NM_001270470 /// NM_001270471 /// NM_003877 /// XM_005269213 /// XM_006719673 /// XM_006719674 0001558 // regulation of cell growth // non-traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005131 // growth hormone receptor binding // non-traceable author statement /// 0005148 // prolactin receptor binding // non-traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008269 // JAK pathway signal transduction adaptor activity // inferred from electronic annotation 203373_at NM_003877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003877.1 /DEF=Homo sapiens STAT induced STAT inhibitor-2 (STATI2), mRNA. /FEA=mRNA /GEN=STATI2 /PROD=STAT induced STAT inhibitor-2 /DB_XREF=gi:4507262 /UG=Hs.110776 STAT induced STAT inhibitor-2 /FL=gb:AB004903.1 gb:AB006966.1 gb:AF037989.1 gb:AF020590.1 gb:NM_003877.1 NM_003877 suppressor of cytokine signaling 2 SOCS2 8835 NM_001270467 /// NM_001270468 /// NM_001270469 /// NM_001270470 /// NM_001270471 /// NM_003877 /// XM_005269213 /// XM_006719673 /// XM_006719674 0001558 // regulation of cell growth // non-traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005131 // growth hormone receptor binding // non-traceable author statement /// 0005148 // prolactin receptor binding // non-traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008269 // JAK pathway signal transduction adaptor activity // inferred from electronic annotation 203374_s_at AW612376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW612376 /FEA=EST /DB_XREF=gi:7317562 /DB_XREF=est:hg99b11.x1 /CLONE=IMAGE:2953725 /UG=Hs.1117 tripeptidyl peptidase II /FL=gb:M73047.1 gb:NM_003291.1 AW612376 tripeptidyl peptidase II TPP2 7174 NM_003291 /// XM_005254070 /// XM_005254071 /// XM_005254072 /// XM_005254073 /// XR_243046 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004175 // endopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008240 // tripeptidyl-peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203375_s_at NM_003291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003291.1 /DEF=Homo sapiens tripeptidyl peptidase II (TPP2), mRNA. /FEA=mRNA /GEN=TPP2 /PROD=tripeptidyl peptidase II /DB_XREF=gi:4507656 /UG=Hs.1117 tripeptidyl peptidase II /FL=gb:M73047.1 gb:NM_003291.1 NM_003291 tripeptidyl peptidase II TPP2 7174 NM_003291 /// XM_005254070 /// XM_005254071 /// XM_005254072 /// XM_005254073 /// XR_243046 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004175 // endopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008240 // tripeptidyl-peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203376_at BG528818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG528818 /FEA=EST /DB_XREF=gi:13520355 /DB_XREF=est:602579703F1 /CLONE=IMAGE:4713600 /UG=Hs.116674 pre-mRNA splicing factor 17 /FL=gb:AF038392.1 gb:AF061241.1 gb:NM_015891.1 BG528818 cell division cycle 40 CDC40 51362 NM_015891 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203377_s_at NM_015891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015891.1 /DEF=Homo sapiens pre-mRNA splicing factor (PRP17), mRNA. /FEA=mRNA /GEN=PRP17 /PROD=pre-mRNA splicing factor /DB_XREF=gi:7706656 /UG=Hs.116674 pre-mRNA splicing factor 17 /FL=gb:AF038392.1 gb:AF061241.1 gb:NM_015891.1 NM_015891 cell division cycle 40 CDC40 51362 NM_015891 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203378_at AB020631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020631.1 /DEF=Homo sapiens mRNA for KIAA0824 protein, partial cds. /FEA=mRNA /GEN=KIAA0824 /PROD=KIAA0824 protein /DB_XREF=gi:4240136 /UG=Hs.123654 PCF11p homolog /FL=gb:AF046935.1 gb:NM_015885.1 AB020631 PCF11 cleavage and polyadenylation factor subunit PCF11 51585 NM_015885 /// XM_005274048 /// XM_005274049 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006379 // mRNA cleavage // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005849 // mRNA cleavage factor complex // non-traceable author statement 203379_at NM_002953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002953.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 90kD, polypeptide 1 (RPS6KA1), mRNA. /FEA=mRNA /GEN=RPS6KA1 /PROD=ribosomal protein S6 kinase, 90kD, polypeptide1 /DB_XREF=gi:4506732 /UG=Hs.149957 ribosomal protein S6 kinase, 90kD, polypeptide 1 /FL=gb:L07597.1 gb:NM_002953.1 NM_002953 ribosomal protein S6 kinase, 90kDa, polypeptide 1 RPS6KA1 6195 NM_001006665 /// NM_002953 /// XM_005245966 /// XM_005245967 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043555 // regulation of translation in response to stress // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 2000491 // positive regulation of hepatic stellate cell activation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203380_x_at NM_006925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006925.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 5 (SFRS5), mRNA. /FEA=mRNA /GEN=SFRS5 /PROD=splicing factor, arginineserine-rich 5 /DB_XREF=gi:5902077 /UG=Hs.166975 splicing factor, arginineserine-rich 5 /FL=gb:U30827.1 gb:NM_006925.1 NM_006925 serine/arginine-rich splicing factor 5 SRSF5 6430 NM_001039465 /// NM_006925 /// XM_005267998 /// XM_005267999 /// XM_005268000 /// XM_005268001 /// XR_429326 /// XR_429327 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 203381_s_at N33009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N33009 /FEA=EST /DB_XREF=gi:1153408 /DB_XREF=est:yy31f09.s1 /CLONE=IMAGE:272873 /UG=Hs.169401 apolipoprotein E /FL=gb:BC003557.1 gb:M12529.1 gb:K00396.1 gb:NM_000041.1 N33009 apolipoprotein E APOE 348 NM_000041 /// XM_005258867 0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 203382_s_at NM_000041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000041.1 /DEF=Homo sapiens apolipoprotein E (APOE), mRNA. /FEA=mRNA /GEN=APOE /PROD=apolipoprotein E /DB_XREF=gi:4557324 /UG=Hs.169401 apolipoprotein E /FL=gb:BC003557.1 gb:M12529.1 gb:K00396.1 gb:NM_000041.1 NM_000041 apolipoprotein E APOE 348 NM_000041 /// XM_005258867 0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 203383_s_at BG111661 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG111661 /FEA=EST /DB_XREF=gi:12605167 /DB_XREF=est:602285419F1 /CLONE=IMAGE:4372612 /UG=Hs.172647 golgi autoantigen, golgin subfamily a, 1 /FL=gb:U51587.1 gb:NM_002077.1 BG111661 golgin A1 GOLGA1 2800 NM_002077 /// XM_005251929 /// XM_006717062 /// XM_006717063 0000042 // protein targeting to Golgi // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203384_s_at NM_002077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002077.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 1 (GOLGA1), mRNA. /FEA=mRNA /GEN=GOLGA1 /PROD=golgin 97 /DB_XREF=gi:4504062 /UG=Hs.172647 golgi autoantigen, golgin subfamily a, 1 /FL=gb:U51587.1 gb:NM_002077.1 NM_002077 golgin A1 GOLGA1 2800 NM_002077 /// XM_005251929 /// XM_006717062 /// XM_006717063 0000042 // protein targeting to Golgi // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203385_at NM_001345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001345.1 /DEF=Homo sapiens diacylglycerol kinase, alpha (80kD) (DGKA), mRNA. /FEA=mRNA /GEN=DGKA /PROD=diacylglycerol kinase, alpha (80kD) /DB_XREF=gi:11415023 /UG=Hs.172690 diacylglycerol kinase, alpha (80kD) /FL=gb:NM_001345.1 gb:AF064770.1 NM_001345 diacylglycerol kinase, alpha 80kDa DGKA 1606 NM_001345 /// NM_201444 /// NM_201445 /// NM_201554 /// XM_005268688 /// XM_005268689 /// XM_005268690 /// XM_006719260 /// XR_429084 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203386_at AI650848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI650848 /FEA=EST /DB_XREF=gi:4734827 /DB_XREF=est:wa95d04.x1 /CLONE=IMAGE:2303911 /UG=Hs.173802 KIAA0603 gene product /FL=gb:AB011175.1 gb:NM_014832.1 AI650848 TBC1 domain family, member 4 TBC1D4 9882 NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903 0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203387_s_at NM_014832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014832.1 /DEF=Homo sapiens KIAA0603 gene product (KIAA0603), mRNA. /FEA=mRNA /GEN=KIAA0603 /PROD=KIAA0603 gene product /DB_XREF=gi:7662197 /UG=Hs.173802 KIAA0603 gene product /FL=gb:AB011175.1 gb:NM_014832.1 NM_014832 TBC1 domain family, member 4 TBC1D4 9882 NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903 0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203388_at NM_004313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004313.1 /DEF=Homo sapiens arrestin, beta 2 (ARRB2), mRNA. /FEA=mRNA /GEN=ARRB2 /PROD=arrestin beta 2 /DB_XREF=gi:4757779 /UG=Hs.18142 arrestin, beta 2 /FL=gb:AF106941.1 gb:NM_004313.1 NM_004313 arrestin, beta 2 ARRB2 409 NM_001257328 /// NM_001257329 /// NM_001257330 /// NM_001257331 /// NM_004313 /// NM_199004 /// NR_047516 /// XM_006721520 /// XM_006721521 /// XR_429814 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002032 // desensitization of G-protein coupled receptor protein signaling pathway by arrestin // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from genetic interaction /// 0031623 // receptor internalization // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032226 // positive regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045953 // negative regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031826 // type 2A serotonin receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 203389_at AF035621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035621.1 /DEF=Homo sapiens kinesin-related protein (KIF3C) mRNA, complete cds. /FEA=mRNA /GEN=KIF3C /PROD=kinesin-related protein /DB_XREF=gi:2815621 /UG=Hs.21611 kinesin family member 3C /FL=gb:AF018164.1 gb:AF035621.1 gb:NM_002254.1 AF035621 kinesin family member 3C KIF3C 3797 NM_002254 /// XM_005264299 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203390_s_at NM_002254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002254.1 /DEF=Homo sapiens kinesin family member 3C (KIF3C), mRNA. /FEA=mRNA /GEN=KIF3C /PROD=kinesin family member 3C /DB_XREF=gi:4504868 /UG=Hs.21611 kinesin family member 3C /FL=gb:AF018164.1 gb:AF035621.1 gb:NM_002254.1 NM_002254 kinesin family member 3C KIF3C 3797 NM_002254 /// XM_005264299 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203391_at NM_004470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004470.1 /DEF=Homo sapiens FK506-binding protein 2 (13kD) (FKBP2), mRNA. /FEA=mRNA /GEN=FKBP2 /PROD=FK506-binding protein 2 (13kD) /DB_XREF=gi:4758381 /UG=Hs.227729 FK506-binding protein 2 (13kD) /FL=gb:BC003384.1 gb:M65128.1 gb:M75099.1 gb:NM_004470.1 NM_004470 FK506 binding protein 2, 13kDa FKBP2 2286 NM_001135208 /// NM_004470 /// NM_057092 /// XM_005273848 /// XM_006718476 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // not recorded 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation 203392_s_at NM_001328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001328.1 /DEF=Homo sapiens C-terminal binding protein 1 (CTBP1), mRNA. /FEA=mRNA /GEN=CTBP1 /PROD=C-terminal binding protein 1 /DB_XREF=gi:4557496 /UG=Hs.239737 C-terminal binding protein 1 /FL=gb:U37408.1 gb:AF091555.1 gb:NM_001328.1 NM_001328 C-terminal binding protein 1 CTBP1 1487 NM_001012614 /// NM_001328 /// XM_005272261 /// XM_005272262 /// XM_005272263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007030 // Golgi organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from mutant phenotype /// 0034401 // regulation of transcription by chromatin organization // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090241 // negative regulation of histone H4 acetylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 203393_at BE973687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE973687 /FEA=EST /DB_XREF=gi:10587023 /DB_XREF=est:601680868F1 /CLONE=IMAGE:3951041 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2 BE973687 hes family bHLH transcription factor 1 HES1 3280 NM_005524 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203394_s_at BE973687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE973687 /FEA=EST /DB_XREF=gi:10587023 /DB_XREF=est:601680868F1 /CLONE=IMAGE:3951041 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2 BE973687 hes family bHLH transcription factor 1 HES1 3280 NM_005524 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203395_s_at NM_005524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005524.2 /DEF=Homo sapiens hairy (Drosophila)-homolog (HRY), mRNA. /FEA=mRNA /GEN=HRY /PROD=hairy (Drosophila)-homolog /DB_XREF=gi:8400709 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2 NM_005524 hes family bHLH transcription factor 1 HES1 3280 NM_005524 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203396_at NM_002789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002789.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 4 (PSMA4), mRNA. /FEA=mRNA /GEN=PSMA4 /PROD=proteasome (prosome, macropain) subunit, alphatype, 4 /DB_XREF=gi:4506184 /UG=Hs.251531 proteasome (prosome, macropain) subunit, alpha type, 4 /FL=gb:BC005361.1 gb:NM_002789.1 NM_002789 proteasome (prosome, macropain) subunit, alpha type, 4 PSMA4 5685 NM_001102667 /// NM_001102668 /// NM_002789 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203397_s_at BF063271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF063271 /FEA=EST /DB_XREF=gi:10822181 /DB_XREF=est:7h87d05.x1 /CLONE=IMAGE:3322953 /UG=Hs.278611 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) /FL=gb:NM_004482.2 BF063271 polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 2591 NM_004482 /// XM_005246449 /// XM_006712402 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203398_s_at NM_004482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004482.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3), mRNA. /FEA=mRNA /GEN=GALNT3 /PROD=polypeptide N-acetylgalactosaminyltransferase 3 /DB_XREF=gi:9945386 /UG=Hs.278611 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) /FL=gb:NM_004482.2 NM_004482 polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 2591 NM_004482 /// XM_005246449 /// XM_006712402 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203399_x_at NM_021016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021016.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 3 (PSG3), mRNA. /FEA=mRNA /GEN=PSG3 /PROD=pregnancy specific beta-1-glycoprotein 3 /DB_XREF=gi:11036637 /UG=Hs.282847 pregnancy specific beta-1-glycoprotein 3 /FL=gb:NM_021016.1 gb:M34420.1 gb:M23575.1 gb:M93061.1 NM_021016 pregnancy specific beta-1-glycoprotein 11 /// pregnancy specific beta-1-glycoprotein 3 PSG11 /// PSG3 5671 /// 5680 NM_001113410 /// NM_002785 /// NM_021016 /// NM_203287 0006952 // defense response // traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203400_s_at NM_001063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001063.1 /DEF=Homo sapiens transferrin (TF), mRNA. /FEA=mRNA /GEN=TF /PROD=transferrin precursor /DB_XREF=gi:4557870 /UG=Hs.284176 transferrin /FL=gb:M12530.1 gb:NM_001063.1 NM_001063 transferrin TF 7018 NM_001063 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030120 // vesicle coat // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097433 // dense body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203401_at NM_002765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002765.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase 2 (PRPS2), mRNA. /FEA=mRNA /GEN=PRPS2 /PROD=phosphoribosyl pyrophosphate synthetase 2 /DB_XREF=gi:4506128 /UG=Hs.2910 phosphoribosyl pyrophosphate synthetase 2 /FL=gb:NM_002765.1 NM_002765 phosphoribosyl pyrophosphate synthetase 2 PRPS2 5634 NM_001039091 /// NM_002765 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044249 // cellular biosynthetic process // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043531 // ADP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203402_at AL520102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL520102 /FEA=EST /DB_XREF=gi:12783595 /DB_XREF=est:AL520102 /CLONE=CS0DB005YO14 (3 prime) /UG=Hs.298184 potassium voltage-gated channel, shaker-related subfamily, beta member 2 /FL=gb:U33429.1 gb:AF029749.1 gb:NM_003636.1 AL520102 potassium voltage-gated channel, shaker-related subfamily, beta member 2 KCNAB2 8514 NM_001199860 /// NM_001199861 /// NM_001199862 /// NM_001199863 /// NM_003636 /// NM_172130 /// XM_005263511 /// XM_005263512 /// XM_005263513 /// XM_005263514 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 203403_s_at NM_005977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005977.1 /DEF=Homo sapiens ring finger protein (C3H2C3 type) 6 (RNF6), mRNA. /FEA=mRNA /GEN=RNF6 /PROD=ring finger protein (C3H2C3 type) 6 /DB_XREF=gi:5174652 /UG=Hs.32597 ring finger protein (C3H2C3 type) 6 /FL=gb:NM_005977.1 NM_005977 ring finger protein (C3H2C3 type) 6 RNF6 6049 NM_005977 /// NM_183043 /// NM_183044 /// NM_183045 /// XM_005266485 /// XM_005266486 /// XM_006719854 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from sequence or structural similarity /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 203404_at NM_014782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014782.1 /DEF=Homo sapiens KIAA0512 gene product (KIAA0512), mRNA. /FEA=mRNA /GEN=KIAA0512 /PROD=KIAA0512 gene product /DB_XREF=gi:7662161 /UG=Hs.48924 KIAA0512 gene product; ALEX2 /FL=gb:AB011084.1 gb:NM_014782.1 NM_014782 armadillo repeat containing, X-linked 2 ARMCX2 9823 NM_001282231 /// NM_014782 /// NM_177949 /// XM_005278109 /// XM_005278110 /// XM_005278111 /// XM_005278113 /// XM_005278114 /// XM_005278115 /// XM_005278116 /// XM_005278117 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203405_at NM_003720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003720.1 /DEF=Homo sapiens Down syndrome critical region gene 2 (DSCR2), mRNA. /FEA=mRNA /GEN=DSCR2 /PROD=Down syndrome critical region protein 2 /DB_XREF=gi:4505022 /UG=Hs.5198 Down syndrome critical region gene 2 /FL=gb:BC003619.1 gb:NM_003720.1 NM_003720 proteasome (prosome, macropain) assembly chaperone 1 PSMG1 8624 NM_001261824 /// NM_003720 /// NM_203433 /// NR_049728 0043248 // proteasome assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203406_at NM_005926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005926.1 /DEF=Homo sapiens microfibrillar-associated protein 1 (MFAP1), mRNA. /FEA=mRNA /GEN=MFAP1 /PROD=microfibrillar-associated protein 1 /DB_XREF=gi:5174552 /UG=Hs.61418 microfibrillar-associated protein 1 /FL=gb:U04209.1 gb:NM_005926.1 NM_005926 microfibrillar-associated protein 1 MFAP1 4236 NM_005926 0030198 // extracellular matrix organization // traceable author statement 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203407_at NM_002705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002705.1 /DEF=Homo sapiens periplakin (PPL), mRNA. /FEA=mRNA /GEN=PPL /PROD=periplakin /DB_XREF=gi:4505992 /UG=Hs.74304 periplakin /FL=gb:AF001691.1 gb:NM_002705.1 NM_002705 periplakin PPL 5493 NM_002705 /// XM_006720902 0031424 // keratinization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203408_s_at NM_002971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002971.1 /DEF=Homo sapiens special AT-rich sequence binding protein 1 (binds to nuclear matrixscaffold-associating DNAs) (SATB1), mRNA. /FEA=mRNA /GEN=SATB1 /PROD=special AT-rich sequence binding protein 1(binds to nuclear matrixscaffold-associating DNAs) /DB_XREF=gi:4506790 /UG=Hs.74592 special AT-rich sequence binding protein 1 (binds to nuclear matrixscaffold-associating DNAs) /FL=gb:M97287.1 gb:NM_002971.1 NM_002971 SATB homeobox 1 SATB1 6304 NM_001131010 /// NM_001195470 /// NM_002971 /// XM_006713280 /// XM_006713281 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0043367 // CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0060004 // reflex // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203409_at NM_000107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000107.1 /DEF=Homo sapiens damage-specific DNA binding protein 2 (48kD) (DDB2), mRNA. /FEA=mRNA /GEN=DDB2 /PROD=damage-specific DNA binding protein 2 (48kD) /DB_XREF=gi:4557514 /UG=Hs.77602 damage-specific DNA binding protein 2 (48kD) /FL=gb:BC000093.1 gb:U18300.1 gb:NM_000107.1 NM_000107 damage-specific DNA binding protein 2, 48kDa DDB2 1643 NM_000107 /// XM_005252808 /// XM_006718161 /// XR_242780 0000209 // protein polyubiquitination // inferred from direct assay /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070914 // UV-damage excision repair // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203410_at NM_006803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006803.1 /DEF=Homo sapiens adaptor-related protein complex 3, mu 2 subunit (AP3M2), mRNA. /FEA=mRNA /GEN=AP3M2 /PROD=adaptor-related protein complex 3, mu 2 subunit /DB_XREF=gi:5802999 /UG=Hs.77770 adaptor-related protein complex 3, mu 2 subunit /FL=gb:NM_006803.1 gb:D38293.1 NM_006803 adaptor-related protein complex 3, mu 2 subunit AP3M2 10947 NM_001134296 /// NM_006803 /// XM_006716276 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203411_s_at NM_005572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005572.1 /DEF=Homo sapiens lamin AC (LMNA), mRNA. /FEA=mRNA /GEN=LMNA /PROD=lamin AC /DB_XREF=gi:5031874 /UG=Hs.77886 lamin AC /FL=gb:BC000511.1 gb:BC003162.1 gb:M13451.1 gb:NM_005572.1 NM_005572 lamin A/C LMNA 4000 NM_001257374 /// NM_001282624 /// NM_001282625 /// NM_001282626 /// NM_005572 /// NM_170707 /// NM_170708 0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203412_at NM_006767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006767.1 /DEF=Homo sapiens leucine-zipper-like transcriptional regulator, 1 (LZTR1), mRNA. /FEA=mRNA /GEN=LZTR1 /PROD=leucine-zipper-like transcriptional regulator,1 /DB_XREF=gi:5803073 /UG=Hs.78788 leucine-zipper-like transcriptional regulator, 1 /FL=gb:NM_006767.1 gb:D38496.1 NM_006767 leucine-zipper-like transcription regulator 1 LZTR1 8216 NM_006767 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203413_at NM_006159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006159.1 /DEF=Homo sapiens nel (chicken)-like 2 (NELL2), mRNA. /FEA=mRNA /GEN=NELL2 /PROD=nel (chicken)-like 2 /DB_XREF=gi:5453765 /UG=Hs.79389 nel (chicken)-like 2 /FL=gb:D83018.1 gb:NM_006159.1 NM_006159 NEL-like 2 (chicken) NELL2 4753 NM_001145107 /// NM_001145108 /// NM_001145109 /// NM_001145110 /// NM_006159 /// XM_005268905 0007155 // cell adhesion // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 203414_at NM_012329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012329.1 /DEF=Homo sapiens monocyte to macrophage differentiation-associated (MMD), mRNA. /FEA=mRNA /GEN=MMD /PROD=monocyte to macrophagedifferentiation-associated, precursor /DB_XREF=gi:6912507 /UG=Hs.79889 monocyte to macrophage differentiation-associated /FL=gb:NM_012329.1 NM_012329 monocyte to macrophage differentiation-associated MMD 23531 NM_012329 /// XM_006721795 /// XR_429880 0019835 // cytolysis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement 203415_at NM_013232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013232.1 /DEF=Homo sapiens programmed cell death 6 (PDCD6), mRNA. /FEA=mRNA /GEN=PDCD6 /PROD=programmed cell death 6 /DB_XREF=gi:7019484 /UG=Hs.80019 programmed cell death 6 /FL=gb:AF035606.1 gb:U58773.1 gb:NM_013232.1 NM_013232 programmed cell death 6 PDCD6 10016 NM_001267556 /// NM_001267557 /// NM_001267558 /// NM_001267559 /// NM_013232 /// NR_073609 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032007 // negative regulation of TOR signaling // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0036324 // vascular endothelial growth factor receptor-2 signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from mutant phenotype 203416_at NM_000560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000560.1 /DEF=Homo sapiens CD53 antigen (CD53), mRNA. /FEA=mRNA /GEN=CD53 /PROD=CD53 antigen /DB_XREF=gi:10834971 /UG=Hs.82212 CD53 antigen /FL=gb:NM_000560.1 gb:M60871.1 gb:M37033.1 NM_000560 CD53 molecule CD53 963 NM_000560 /// NM_001040033 /// XM_006711053 0007165 // signal transduction // non-traceable author statement /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203417_at NM_017459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017459.1 /DEF=Homo sapiens microfibrillar-associated protein 2 (MFAP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=MFAP2 /PROD=microfibrillar-associated protein 2 precursor /DB_XREF=gi:9665258 /UG=Hs.83551 microfibrillar-associated protein 2 /FL=gb:U19718.1 gb:NM_017459.1 gb:NM_002403.2 NM_017459 microfibrillar-associated protein 2 MFAP2 4237 NM_001135247 /// NM_001135248 /// NM_002403 /// NM_017459 0030198 // extracellular matrix organization // traceable author statement /// 0030220 // platelet formation // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 203418_at NM_001237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001237.1 /DEF=Homo sapiens cyclin A2 (CCNA2), mRNA. /FEA=mRNA /GEN=CCNA2 /PROD=cyclin A /DB_XREF=gi:4502612 /UG=Hs.85137 cyclin A2 /FL=gb:NM_001237.1 NM_001237 cyclin A2 CCNA2 890 NM_001237 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 203419_at NM_014727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014727.1 /DEF=Homo sapiens KIAA0304 gene product (KIAA0304), mRNA. /FEA=mRNA /GEN=KIAA0304 /PROD=KIAA0304 gene product /DB_XREF=gi:7662045 /UG=Hs.92236 KIAA0304 gene product /FL=gb:NM_014727.1 NM_014727 lysine (K)-specific methyltransferase 2B KMT2B 9757 NM_014727 /// XM_006723513 /// XM_006723514 /// XM_006723515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009994 // oocyte differentiation // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // non-traceable author statement /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203420_at NM_016255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016255.1 /DEF=Homo sapiens Autosomal Highly Conserved Protein (AHCP), mRNA. /FEA=mRNA /GEN=AHCP /PROD=Autosomal Highly Conserved Protein /DB_XREF=gi:7705267 /UG=Hs.95260 Autosomal Highly Conserved Protein /FL=gb:AF097027.1 gb:NM_016255.1 NM_016255 family with sequence similarity 8, member A1 FAM8A1 51439 NM_016255 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203421_at NM_006034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006034.1 /DEF=Homo sapiens p53-induced protein (PIG11), mRNA. /FEA=mRNA /GEN=PIG11 /PROD=p53-induced protein /DB_XREF=gi:5174630 /UG=Hs.96908 p53-induced protein /FL=gb:BC000443.1 gb:BC003010.1 gb:AF010315.1 gb:NM_006034.1 NM_006034 tumor protein p53 inducible protein 11 TP53I11 9537 NM_001076787 /// NM_001258320 /// NM_001258321 /// NM_001258322 /// NM_001258323 /// NM_001258324 /// NM_006034 /// XM_005253227 /// XM_005253229 /// XM_006718387 /// XR_242833 /// XR_428864 0006950 // response to stress // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203422_at NM_002691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002691.1 /DEF=Homo sapiens polymerase (DNA directed), delta 1, catalytic subunit (125kD) (POLD1), mRNA. /FEA=mRNA /GEN=POLD1 /PROD=polymerase (DNA directed), delta 1, catalyticsubunit (125kD) /DB_XREF=gi:4505932 /UG=Hs.99890 polymerase (DNA directed), delta 1, catalytic subunit (125kD) /FL=gb:M80397.1 gb:M81735.1 gb:NM_002691.1 NM_002691 polymerase (DNA directed), delta 1, catalytic subunit POLD1 5424 NM_001256849 /// NM_002691 /// NR_046402 /// XM_005259006 /// XM_005259007 /// XM_005259008 /// XM_006723248 0000084 // mitotic S phase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from direct assay /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred by curator /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0007346 // regulation of mitotic cell cycle // not recorded /// 0009411 // response to UV // traceable author statement /// 0019985 // translesion synthesis // not recorded /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043137 // DNA replication, removal of RNA primer // not recorded /// 0044281 // small molecule metabolic process // traceable author statement /// 0045004 // DNA replication proofreading // not recorded /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // not recorded /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0043625 // delta DNA polymerase complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 203423_at NM_002899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002899.2 /DEF=Homo sapiens retinol-binding protein 1, cellular (RBP1), mRNA. /FEA=mRNA /GEN=RBP1 /PROD=retinol-binding protein 1, cellular /DB_XREF=gi:8400726 /UG=Hs.101850 retinol-binding protein 1, cellular /FL=gb:M11433.1 gb:NM_002899.2 NM_002899 retinol binding protein 1, cellular RBP1 5947 NM_001130992 /// NM_001130993 /// NM_002899 0001523 // retinoid metabolic process // traceable author statement /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0006776 // vitamin A metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 203424_s_at AW157548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157548 /FEA=EST /DB_XREF=gi:6228949 /DB_XREF=est:au83f04.x1 /CLONE=IMAGE:2782879 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1 AW157548 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203425_s_at NM_000599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000599.1 /DEF=Homo sapiens insulin-like growth factor binding protein 5 (IGFBP5), mRNA. /FEA=mRNA /GEN=IGFBP5 /PROD=insulin-like growth factor binding protein 5 /DB_XREF=gi:10834981 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1 NM_000599 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203426_s_at M65062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M65062.1 /DEF=Human insulin-like growth factor binding protein 5 (IGFBP-5) mRNA, complete cds. /FEA=mRNA /GEN=IGFBP5 /PROD=insulin-like growth factor binding protein 5 /DB_XREF=gi:184819 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1 M65062 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203427_at NM_014034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014034.1 /DEF=Homo sapiens DKFZP547E2110 protein (DKFZP547E2110), mRNA. /FEA=mRNA /GEN=DKFZP547E2110 /PROD=DKFZP547E2110 protein /DB_XREF=gi:7661591 /UG=Hs.108110 DKFZP547E2110 protein /FL=gb:AL050261.1 gb:AF151856.1 gb:AF161495.1 gb:NM_014034.1 gb:AB028628.1 NM_014034 anti-silencing function 1A histone chaperone ASF1A 25842 NM_014034 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031936 // negative regulation of chromatin silencing // non-traceable author statement /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 203428_s_at AB028628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB028628.1 /DEF=Homo sapiens mRNA for CIA, complete cds. /FEA=mRNA /PROD=CIA /DB_XREF=gi:8439508 /UG=Hs.108110 DKFZP547E2110 protein /FL=gb:AL050261.1 gb:AF151856.1 gb:AF161495.1 gb:NM_014034.1 gb:AB028628.1 AB028628 anti-silencing function 1A histone chaperone ASF1A 25842 NM_014034 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031936 // negative regulation of chromatin silencing // non-traceable author statement /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 203429_s_at NM_016227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016227.1 /DEF=Homo sapiens membrane protein CH1 (CH1), mRNA. /FEA=mRNA /GEN=CH1 /PROD=membrane protein CH1 /DB_XREF=gi:7705321 /UG=Hs.108636 membrane protein CH1 /FL=gb:AF097535.1 gb:NM_016227.1 NM_016227 SUN domain containing ossification factor SUCO 51430 NM_001282750 /// NM_001282751 /// NM_014283 /// NM_016227 /// XM_005245251 /// XM_006711374 /// XM_006711375 /// XM_006711376 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0046850 // regulation of bone remodeling // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation 203430_at NM_014320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014320.1 /DEF=Homo sapiens putative heme-binding protein (SOUL), mRNA. /FEA=mRNA /GEN=SOUL /PROD=putative heme-binding protein /DB_XREF=gi:7657602 /UG=Hs.111029 putative heme-binding protein /FL=gb:AF117616.1 gb:NM_014320.1 NM_014320 heme binding protein 2 HEBP2 23593 NM_014320 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0035794 // positive regulation of mitochondrial membrane permeability // inferred from mutant phenotype /// 1901031 // regulation of response to reactive oxygen species // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203431_s_at NM_014715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014715.1 /DEF=Homo sapiens KIAA0712 gene product (KIAA0712), mRNA. /FEA=mRNA /GEN=KIAA0712 /PROD=KIAA0712 gene product /DB_XREF=gi:7662261 /UG=Hs.111138 KIAA0712 gene product /FL=gb:AB018255.1 gb:NM_014715.1 NM_014715 Rho GTPase activating protein 32 ARHGAP32 9743 NM_001142685 /// NM_014715 /// XM_005271736 /// XM_006718947 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 203432_at AW272611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW272611 /FEA=EST /DB_XREF=gi:6659725 /DB_XREF=est:xu22h03.x1 /CLONE=IMAGE:2800949 /UG=Hs.11355 thymopoietin /FL=gb:NM_003276.1 gb:U09086.1 AW272611 thymopoietin TMPO 7112 NM_001032283 /// NM_001032284 /// NM_003276 /// XM_005269130 /// XM_005269132 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement 203433_at NM_006441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006441.1 /DEF=Homo sapiens 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS), mRNA. /FEA=mRNA /GEN=MTHFS /PROD=5,10-methenyltetrahydrofolate synthetase(5-formyltetrahydrofolate cyclo-ligase) /DB_XREF=gi:5453745 /UG=Hs.118131 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) /FL=gb:NM_006441.1 gb:L38928.1 NM_006441 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) /// ST20-MTHFS readthrough MTHFS /// ST20-MTHFS 10588 /// 100528021 NM_001199758 /// NM_001199760 /// NM_006441 /// NR_037654 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0015942 // formate metabolic process // non-traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005542 // folic acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030272 // 5-formyltetrahydrofolate cyclo-ligase activity // inferred from direct assay /// 0030272 // 5-formyltetrahydrofolate cyclo-ligase activity // non-traceable author statement 203434_s_at AI433463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI433463 /FEA=EST /DB_XREF=gi:4289355 /DB_XREF=est:ti65g11.x1 /CLONE=IMAGE:2136932 /UG=Hs.1298 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) /FL=gb:J03779.1 gb:NM_007287.1 gb:NM_007288.1 AI433463 membrane metallo-endopeptidase MME 4311 NM_000902 /// NM_007287 /// NM_007288 /// NM_007289 /// XM_006713646 /// XM_006713647 0001822 // kidney development // inferred from expression pattern /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006518 // peptide metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046449 // creatinine metabolic process // inferred from mutant phenotype /// 0050435 // beta-amyloid metabolic process // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay /// 0090399 // replicative senescence // inferred from expression pattern 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203435_s_at NM_007287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007287.1 /DEF=Homo sapiens membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) (MME), transcript variant 1bis, mRNA. /FEA=mRNA /GEN=MME /PROD=membrane metallo-endopeptidase /DB_XREF=gi:6042199 /UG=Hs.1298 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) /FL=gb:J03779.1 gb:NM_007287.1 gb:NM_007288.1 NM_007287 membrane metallo-endopeptidase MME 4311 NM_000902 /// NM_007287 /// NM_007288 /// NM_007289 /// XM_006713646 /// XM_006713647 0001822 // kidney development // inferred from expression pattern /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006518 // peptide metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046449 // creatinine metabolic process // inferred from mutant phenotype /// 0050435 // beta-amyloid metabolic process // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay /// 0090399 // replicative senescence // inferred from expression pattern 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203436_at NM_006413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006413.1 /DEF=Homo sapiens ribonuclease P (30kD) (RPP30), mRNA. /FEA=mRNA /GEN=RPP30 /PROD=ribonuclease P (30kD) /DB_XREF=gi:5454023 /UG=Hs.139120 ribonuclease P (30kD) /FL=gb:U77665.1 gb:NM_006413.1 NM_006413 ribonuclease P/MRP 30kDa subunit RPP30 10556 NM_001104546 /// NM_006413 /// XM_006717546 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005634 // nucleus // traceable author statement /// 0005655 // nucleolar ribonuclease P complex // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203437_at NM_003876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003876.1 /DEF=Homo sapiens putative receptor protein (PMI), mRNA. /FEA=mRNA /GEN=PMI /PROD=putative receptor protein /DB_XREF=gi:4505900 /UG=Hs.15196 putative receptor protein /FL=gb:BC002819.1 gb:BC005268.1 gb:NM_003876.1 NM_003876 transmembrane protein 11 TMEM11 8834 NM_003876 /// NR_024547 0007005 // mitochondrion organization // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203438_at AI435828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI435828 /FEA=EST /DB_XREF=gi:4305913 /DB_XREF=est:th79e05.x1 /CLONE=IMAGE:2124896 /UG=Hs.155223 stanniocalcin 2 /FL=gb:BC000658.1 gb:AF055460.1 gb:AB012664.1 gb:AF098462.1 gb:AF031036.1 gb:NM_003714.1 AI435828 stanniocalcin 2 STC2 8614 NM_003714 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203439_s_at BC000658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000658.1 /DEF=Homo sapiens, stanniocalcin 2, clone MGC:1881, mRNA, complete cds. /FEA=mRNA /PROD=stanniocalcin 2 /DB_XREF=gi:12653744 /UG=Hs.155223 stanniocalcin 2 /FL=gb:BC000658.1 gb:AF055460.1 gb:AB012664.1 gb:AF098462.1 gb:AF031036.1 gb:NM_003714.1 BC000658 stanniocalcin 2 STC2 8614 NM_003714 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203440_at M34064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34064.1 /DEF=Human N-cadherin mRNA, complete cds. /FEA=mRNA /GEN=NCAD /DB_XREF=gi:416292 /UG=Hs.161 cadherin 2, type 1, N-cadherin (neuronal) /FL=gb:M34064.1 gb:NM_001792.1 M34064 cadherin 2, type 1, N-cadherin (neuronal) CDH2 1000 NM_001792 /// XM_005258181 /// XM_005258182 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203441_s_at NM_001792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001792.1 /DEF=Homo sapiens cadherin 2, type 1, N-cadherin (neuronal) (CDH2), mRNA. /FEA=mRNA /GEN=CDH2 /PROD=cadherin 2, type 1, N-cadherin (neuronal) /DB_XREF=gi:4502720 /UG=Hs.161 cadherin 2, type 1, N-cadherin (neuronal) /FL=gb:M34064.1 gb:NM_001792.1 NM_001792 cadherin 2, type 1, N-cadherin (neuronal) CDH2 1000 NM_001792 /// XM_005258181 /// XM_005258182 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203442_x_at AA478965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA478965 /FEA=EST /DB_XREF=gi:2207599 /DB_XREF=est:zv18e01.s1 /CLONE=IMAGE:754008 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1 AA478965 echinoderm microtubule associated protein like 3 EML3 256364 NM_153265 /// XM_005273876 /// XM_005273877 /// XM_005273878 /// XM_006718489 /// XM_006718490 /// XM_006718491 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203443_at AB012922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB012922 /DEF=Homo sapiens MTA1-L1 gene, complete cds /FEA=mRNA /DB_XREF=gi:4126426 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1 AB012922 echinoderm microtubule associated protein like 3 EML3 256364 NM_153265 /// XM_005273876 /// XM_005273877 /// XM_005273878 /// XM_006718489 /// XM_006718490 /// XM_006718491 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203444_s_at NM_004739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004739.1 /DEF=Homo sapiens metastasis-associated 1-like 1 (MTA1L1), mRNA. /FEA=mRNA /GEN=MTA1L1 /PROD=metastasis-associated 1-like 1 /DB_XREF=gi:4758739 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1 NM_004739 metastasis associated 1 family, member 2 MTA2 9219 NM_004739 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203445_s_at NM_005730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005730.1 /DEF=Homo sapiens conserved gene amplified in osteosarcoma (OS4), mRNA. /FEA=mRNA /GEN=OS4 /PROD=conserved gene amplified in osteosarcoma /DB_XREF=gi:5031964 /UG=Hs.180669 conserved gene amplified in osteosarcoma /FL=gb:U81556.1 gb:NM_005730.1 NM_005730 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 CTDSP2 10106 NM_005730 /// XM_005268556 0006470 // protein dephosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008420 // CTD phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203446_s_at NM_000276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000276.2 /DEF=Homo sapiens oculocerebrorenal syndrome of Lowe (OCRL), transcript variant a, mRNA. /FEA=mRNA /GEN=OCRL /PROD=phosphatidylinositol polyphosphate5-phosphatase, isoform a /DB_XREF=gi:13325071 /UG=Hs.181060 oculocerebrorenal syndrome of Lowe /FL=gb:U57627.2 gb:NM_000276.2 NM_000276 oculocerebrorenal syndrome of Lowe OCRL 4952 NM_000276 /// NM_001587 /// XM_005262421 /// XM_005262422 /// XM_006724760 /// XM_006724761 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001750 // photoreceptor outer segment // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // traceable author statement /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0052745 // inositol phosphate phosphatase activity // non-traceable author statement 203447_at AU157008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157008 /FEA=EST /DB_XREF=gi:11018529 /DB_XREF=est:AU157008 /CLONE=PLACE1005711 /UG=Hs.193725 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 /FL=gb:NM_005047.1 AU157008 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 PSMD5 5711 NM_001270427 /// NM_005047 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 203448_s_at AI347136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI347136 /FEA=EST /DB_XREF=gi:4084342 /DB_XREF=est:tc04a11.x1 /CLONE=IMAGE:2062844 /UG=Hs.194562 telomeric repeat binding factor (NIMA-interacting) 1 /FL=gb:U40705.1 gb:NM_017489.1 AI347136 telomeric repeat binding factor (NIMA-interacting) 1 TERF1 7013 NM_003218 /// NM_017489 /// XM_005251291 /// XM_005251292 0000086 // G2/M transition of mitotic cell cycle // inferred from expression pattern /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from genetic interaction /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from sequence or structural similarity /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0010521 // telomerase inhibitor activity // inferred from genetic interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay 203449_s_at NM_017489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017489.1 /DEF=Homo sapiens telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TERF1 /PROD=telomeric repeat binding factor 1, isoform 1 /DB_XREF=gi:9257245 /UG=Hs.194562 telomeric repeat binding factor (NIMA-interacting) 1 /FL=gb:U40705.1 gb:NM_017489.1 NM_017489 telomeric repeat binding factor (NIMA-interacting) 1 TERF1 7013 NM_003218 /// NM_017489 /// XM_005251291 /// XM_005251292 0000086 // G2/M transition of mitotic cell cycle // inferred from expression pattern /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from genetic interaction /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from sequence or structural similarity /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0010521 // telomerase inhibitor activity // inferred from genetic interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay 203450_at NM_015373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015373.1 /DEF=Homo sapiens chromosome 22 open reading frame 2 (C22ORF2), mRNA. /FEA=mRNA /GEN=C22ORF2 /PROD=chromosome 22 open reading frame 2 /DB_XREF=gi:7656941 /UG=Hs.227637 chromosome 22 open reading frame 2 /FL=gb:AL136686.1 gb:NM_015373.1 NM_015373 chibby homolog 1 (Drosophila) CBY1 25776 NM_001002880 /// NM_015373 0008104 // protein localization // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 203451_at NM_003893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003893.1 /DEF=Homo sapiens LIM domain binding 1 (LDB1), mRNA. /FEA=mRNA /GEN=LDB1 /PROD=LIM domain binding 1 /DB_XREF=gi:4504968 /UG=Hs.26002 LIM domain binding 1 /FL=gb:BC000482.1 gb:AB016485.1 gb:AF064491.1 gb:AF068652.1 gb:NM_003893.1 NM_003893 LIM domain binding 1 LDB1 8861 NM_001113407 /// NM_003893 /// XM_005270262 0000972 // transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery // inferred from sequence or structural similarity /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0022607 // cellular component assembly // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043973 // histone H3-K4 acetylation // inferred from sequence or structural similarity /// 0045647 // negative regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046985 // positive regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060322 // head development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043621 // protein self-association // inferred from electronic annotation 203452_at NM_012200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012200.2 /DEF=Homo sapiens beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3GAT3), mRNA. /FEA=mRNA /GEN=B3GAT3 /PROD=beta-1,3-glucuronyltransferase 3 /DB_XREF=gi:12408653 /UG=Hs.26492 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) /FL=gb:NM_012200.2 gb:AB009598.1 NM_012200 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) B3GAT3 26229 NM_001288721 /// NM_001288722 /// NM_001288723 /// NM_012200 /// NR_109991 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015018 // galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity // non-traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203453_at NM_001038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001038.1 /DEF=Homo sapiens sodium channel, nonvoltage-gated 1 alpha (SCNN1A), mRNA. /FEA=mRNA /GEN=SCNN1A /PROD=sodium channel, nonvoltage-gated 1 alpha /DB_XREF=gi:4506814 /UG=Hs.2794 sodium channel, nonvoltage-gated 1 alpha /FL=gb:NM_001038.1 NM_001038 sodium channel, non-voltage-gated 1 alpha subunit SCNN1A 6337 NM_001038 /// NM_001159575 /// NM_001159576 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0034706 // sodium channel complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 203454_s_at NM_004045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004045.1 /DEF=Homo sapiens ATX1 (antioxidant protein 1, yeast) homolog 1 (ATOX1), mRNA. /FEA=mRNA /GEN=ATOX1 /PROD=ATX1 (antioxidant protein 1, yeast) homolog 1 /DB_XREF=gi:4757803 /UG=Hs.279910 ATX1 (antioxidant protein 1, yeast) homolog 1 /FL=gb:NM_004045.1 NM_004045 antioxidant 1 copper chaperone ATOX1 475 NM_004045 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005507 // copper ion binding // inferred from direct assay /// 0016530 // metallochaperone activity // traceable author statement /// 0016531 // copper chaperone activity // inferred from direct assay /// 0032767 // copper-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203455_s_at NM_002970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002970.1 /DEF=Homo sapiens spermidinespermine N1-acetyltransferase (SAT), mRNA. /FEA=mRNA /GEN=SAT /PROD=spermidinespermine N1-acetyltransferase /DB_XREF=gi:4506788 /UG=Hs.28491 spermidinespermine N1-acetyltransferase /FL=gb:BC002503.1 gb:M77693.1 gb:NM_002970.1 NM_002970 spermidine/spermine N1-acetyltransferase 1 SAT1 6303 NM_002970 /// NR_027783 0001525 // angiogenesis // inferred from expression pattern /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009447 // putrescine catabolic process // inferred from electronic annotation /// 0032918 // spermidine acetylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004145 // diamine N-acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019809 // spermidine binding // inferred from electronic annotation 203456_at NM_007213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007213.1 /DEF=Homo sapiens JM4 protein (JM4), mRNA. /FEA=mRNA /GEN=JM4 /PROD=JM4 protein /DB_XREF=gi:6005793 /UG=Hs.29595 JM4 protein /FL=gb:AJ005896.1 gb:NM_007213.1 NM_007213 PRA1 domain family, member 2 PRAF2 11230 NM_007213 0000045 // autophagic vacuole assembly // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // not recorded /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // not recorded 203457_at NM_003569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003569.1 /DEF=Homo sapiens syntaxin 7 (STX7), mRNA. /FEA=mRNA /GEN=STX7 /PROD=syntaxin 7 /DB_XREF=gi:4507294 /UG=Hs.299166 syntaxin 7 /FL=gb:U77942.1 gb:NM_003569.1 NM_003569 syntaxin 7 STX7 8417 NM_003569 0006886 // intracellular protein transport // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0000149 // SNARE binding // inferred from direct assay /// 0005484 // SNAP receptor activity // not recorded 203458_at AI951454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI951454 /FEA=EST /DB_XREF=gi:5743690 /DB_XREF=est:wx67b10.x1 /CLONE=IMAGE:2548699 /UG=Hs.301540 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) /FL=gb:M76231.1 gb:NM_003124.1 AI951454 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) SPR 6697 NM_003124 0006729 // tetrahydrobiopterin biosynthetic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004757 // sepiapterin reductase activity // inferred from sequence or structural similarity /// 0004757 // sepiapterin reductase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement 203459_s_at NM_022575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022575.1 /DEF=Homo sapiens vacuolar protein sorting 16 (yeast homolog) (VPS16), mRNA. /FEA=mRNA /GEN=VPS16 /PROD=vacuolar protein sorting 16 (yeast homolog) /DB_XREF=gi:12007657 /UG=Hs.302441 vacuolar protein sorting 16 (yeast homolog) /FL=gb:AF308801.1 gb:NM_022575.1 NM_022575 vacuolar protein sorting 16 homolog (S. cerevisiae) VPS16 64601 NM_022575 /// NM_080413 /// NM_080414 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 203460_s_at NM_007318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007318.1 /DEF=Homo sapiens presenilin 1 (Alzheimer disease 3) (PSEN1), transcript variant I-463, mRNA. /FEA=mRNA /GEN=PSEN1 /PROD=presenilin 1 isoform I-463 /DB_XREF=gi:7549812 /UG=Hs.3260 presenilin 1 (Alzheimer disease 3) /FL=gb:U40379.1 gb:L76517.1 gb:NM_007318.1 NM_007318 presenilin 1 PSEN1 5663 NM_000021 /// NM_007318 /// NM_007319 /// XM_005267864 /// XM_005267866 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015871 // choline transport // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021870 // Cajal-Retzius cell differentiation // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from genetic interaction /// 0034205 // beta-amyloid formation // inferred from electronic annotation /// 0035282 // segmentation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from electronic annotation /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // not recorded /// 0051604 // protein maturation // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // /// 0060075 // regulation of resting membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0031965 // nuclear membrane // inferred from direct assay /// 0035253 // ciliary rootlet // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // not recorded /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // not recorded /// 0070765 // gamma-secretase complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0045296 // cadherin binding // not recorded 203461_at NM_001271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001271.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), mRNA. /FEA=mRNA /GEN=CHD2 /PROD=chromodomain helicase DNA binding protein 2 /DB_XREF=gi:4557448 /UG=Hs.36787 chromodomain helicase DNA binding protein 2 /FL=gb:AF006514.1 gb:NM_001271.1 NM_001271 chromodomain helicase DNA binding protein 2 CHD2 1106 NM_001042572 /// NM_001271 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 203462_x_at NM_003751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003751.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) (EIF3S9), mRNA. /FEA=mRNA /GEN=EIF3S9 /PROD=eukaryotic translation initiation factor 3,subunit 9 (eta, 116kD) /DB_XREF=gi:4503526 /UG=Hs.57783 eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) /FL=gb:U62583.1 gb:NM_003751.1 NM_003751 eukaryotic translation initiation factor 3, subunit B EIF3B 8662 NM_001037283 /// NM_003751 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // traceable author statement 203463_s_at H05668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H05668 /FEA=EST /DB_XREF=gi:869220 /DB_XREF=est:yl75e11.s1 /CLONE=IMAGE:43677 /UG=Hs.7407 KIAA1065 protein /FL=gb:AF062085.1 gb:AB028988.1 gb:NM_014964.1 H05668 epsin 2 /// EPN2 intronic transcript 1 (non-protein coding) EPN2 /// EPN2-IT1 22905 /// 100874309 NM_001102664 /// NM_014964 /// NM_148921 /// NR_046824 /// XM_005256539 /// XM_006721475 /// XM_006721476 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030128 // clathrin coat of endocytic vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203464_s_at NM_014964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014964.1 /DEF=Homo sapiens KIAA1065 protein (KIAA1065), mRNA. /FEA=mRNA /GEN=KIAA1065 /PROD=KIAA1065 protein /DB_XREF=gi:7662467 /UG=Hs.7407 KIAA1065 protein /FL=gb:AF062085.1 gb:AB028988.1 gb:NM_014964.1 NM_014964 epsin 2 /// EPN2 intronic transcript 1 (non-protein coding) EPN2 /// EPN2-IT1 22905 /// 100874309 NM_001102664 /// NM_014964 /// NM_148921 /// NR_046824 /// XM_005256539 /// XM_006721475 /// XM_006721476 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030128 // clathrin coat of endocytic vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203465_at NM_014763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014763.1 /DEF=Homo sapiens mitochondrial ribosomal protein L19 (MRPL19), mRNA. /FEA=mRNA /GEN=MRPL19 /PROD=mitochondrial ribosomal protein L19 /DB_XREF=gi:7661911 /UG=Hs.75574 mitochondrial ribosomal protein L19 /FL=gb:D14660.1 gb:NM_014763.1 NM_014763 mitochondrial ribosomal protein L19 MRPL19 9801 NM_014763 /// XM_006712155 /// XR_427001 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation 203466_at NM_002437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002437.1 /DEF=Homo sapiens MpV17 transgene, murine homolog, glomerulosclerosis (MPV17), mRNA. /FEA=mRNA /GEN=MPV17 /PROD=MpV17 transgene, murine homolog,glomerulosclerosis /DB_XREF=gi:4505240 /UG=Hs.75659 MpV17 transgene, murine homolog, glomerulosclerosis /FL=gb:BC001115.1 gb:NM_002437.1 NM_002437 MpV17 mitochondrial inner membrane protein MPV17 4358 NM_002437 /// XM_005264326 /// XM_005264327 /// XM_006712021 0000002 // mitochondrial genome maintenance // inferred from mutant phenotype /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from sequence or structural similarity /// 0042592 // homeostatic process // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203467_at NM_002676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002676.1 /DEF=Homo sapiens phosphomannomutase 1 (PMM1), mRNA. /FEA=mRNA /GEN=PMM1 /PROD=phosphomannomutase 1 /DB_XREF=gi:4505904 /UG=Hs.75835 phosphomannomutase 1 /FL=gb:D87810.1 gb:U62526.1 gb:U86070.1 gb:NM_002676.1 NM_002676 phosphomannomutase 1 PMM1 5372 NM_002676 /// XM_005261637 /// XM_005261638 /// XM_005261640 /// XM_005261641 /// XM_005261642 /// XR_430409 0006013 // mannose metabolic process // inferred from direct assay /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019307 // mannose biosynthetic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004615 // phosphomannomutase activity // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203468_at NM_003674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003674.1 /DEF=Homo sapiens cyclin-dependent kinase (CDC2-like) 10 (CDK10), mRNA. /FEA=mRNA /GEN=CDK10 /PROD=cyclin-dependent kinase (CDC2-like) 10 /DB_XREF=gi:4502730 /UG=Hs.77313 cyclin-dependent kinase (CDC2-like) 10 /FL=gb:NM_003674.1 NM_003674 cyclin-dependent kinase 10 CDK10 8558 NM_001098533 /// NM_001160367 /// NM_003674 /// NM_052987 /// NM_052988 /// NR_027702 /// NR_027703 /// XM_006721308 /// XM_006721309 /// XM_006721310 /// XM_006721311 /// XM_006721312 /// XM_006721313 /// XM_006721314 /// XM_006721315 /// XM_006721316 /// XM_006721317 /// XM_006721318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203469_s_at NM_003674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003674.1 /DEF=Homo sapiens cyclin-dependent kinase (CDC2-like) 10 (CDK10), mRNA. /FEA=mRNA /GEN=CDK10 /PROD=cyclin-dependent kinase (CDC2-like) 10 /DB_XREF=gi:4502730 /UG=Hs.77313 cyclin-dependent kinase (CDC2-like) 10 /FL=gb:NM_003674.1 NM_003674 cyclin-dependent kinase 10 CDK10 8558 NM_001098533 /// NM_001160367 /// NM_003674 /// NM_052987 /// NM_052988 /// NR_027702 /// NR_027703 /// XM_006721308 /// XM_006721309 /// XM_006721310 /// XM_006721311 /// XM_006721312 /// XM_006721313 /// XM_006721314 /// XM_006721315 /// XM_006721316 /// XM_006721317 /// XM_006721318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203470_s_at AI433595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI433595 /FEA=EST /DB_XREF=gi:4290278 /DB_XREF=est:ti47f03.x1 /CLONE=IMAGE:2133629 /UG=Hs.77436 pleckstrin /FL=gb:NM_002664.1 AI433595 pleckstrin PLEK 5341 NM_002664 0002244 // hematopoietic progenitor cell differentiation // inferred from expression pattern /// 0002576 // platelet degranulation // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0010920 // negative regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0010925 // positive regulation of inositol-polyphosphate 5-phosphatase activity // inferred from direct assay /// 0030030 // cell projection organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0030845 // phospholipase C-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0033625 // positive regulation of integrin activation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0050849 // negative regulation of calcium-mediated signaling // non-traceable author statement /// 0060305 // regulation of cell diameter // inferred from direct assay /// 0070493 // thrombin receptor signaling pathway // inferred from direct assay /// 0070527 // platelet aggregation // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from sequence or structural similarity /// 0070560 // protein secretion by platelet // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay 0005080 // protein kinase C binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 203471_s_at NM_002664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002664.1 /DEF=Homo sapiens pleckstrin (PLEK), mRNA. /FEA=mRNA /GEN=PLEK /PROD=pleckstrin /DB_XREF=gi:4505878 /UG=Hs.77436 pleckstrin /FL=gb:NM_002664.1 NM_002664 pleckstrin PLEK 5341 NM_002664 0002244 // hematopoietic progenitor cell differentiation // inferred from expression pattern /// 0002576 // platelet degranulation // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0010920 // negative regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0010925 // positive regulation of inositol-polyphosphate 5-phosphatase activity // inferred from direct assay /// 0030030 // cell projection organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0030845 // phospholipase C-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0033625 // positive regulation of integrin activation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0050849 // negative regulation of calcium-mediated signaling // non-traceable author statement /// 0060305 // regulation of cell diameter // inferred from direct assay /// 0070493 // thrombin receptor signaling pathway // inferred from direct assay /// 0070527 // platelet aggregation // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from sequence or structural similarity /// 0070560 // protein secretion by platelet // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay 0005080 // protein kinase C binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 203472_s_at AB026256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026256.1 /DEF=Homo sapiens mRNA for organic anion transporter OATP-B, complete cds. /FEA=mRNA /GEN=OATP-B /PROD=organic anion transporter OATP-B /DB_XREF=gi:5006262 /UG=Hs.7884 solute carrier family 21 (organic anion transporter), member 9 /FL=gb:AB020687.1 gb:AB026256.1 gb:NM_007256.1 AB026256 solute carrier organic anion transporter family, member 2B1 SLCO2B1 11309 NM_001145211 /// NM_001145212 /// NM_007256 /// XM_006718427 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071718 // sodium-independent icosanoid transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay 203473_at NM_007256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007256.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 9 (SLC21A9), mRNA. /FEA=mRNA /GEN=SLC21A9 /PROD=solute carrier family 21 (organic aniontransporter), member 9 /DB_XREF=gi:6005819 /UG=Hs.7884 solute carrier family 21 (organic anion transporter), member 9 /FL=gb:AB020687.1 gb:AB026256.1 gb:NM_007256.1 NM_007256 solute carrier organic anion transporter family, member 2B1 SLCO2B1 11309 NM_001145211 /// NM_001145212 /// NM_007256 /// XM_006718427 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071718 // sodium-independent icosanoid transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay 203474_at NM_006633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006633.1 /DEF=Homo sapiens IQ motif containing GTPase activating protein 2 (IQGAP2), mRNA. /FEA=mRNA /GEN=IQGAP2 /PROD=IQ motif containing GTPase activating protein 2 /DB_XREF=gi:5729886 /UG=Hs.78993 IQ motif containing GTPase activating protein 2 /FL=gb:U51903.1 gb:NM_006633.1 NM_006633 IQ motif containing GTPase activating protein 2 IQGAP2 10788 NM_001285460 /// NM_001285461 /// NM_001285462 /// NM_006633 /// XM_005248409 /// XM_005248410 /// XM_005248411 /// XM_005248413 /// XM_005248414 /// XM_006714522 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay 203475_at NM_000103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000103.1 /DEF=Homo sapiens cytochrome P450, subfamily XIX (aromatization of androgens) (CYP19), mRNA. /FEA=mRNA /GEN=CYP19 /PROD=cytochrome P450, subfamily XIX (aromatization ofandrogens) /DB_XREF=gi:4503196 /UG=Hs.79946 cytochrome P450, subfamily XIX (aromatization of androgens) /FL=gb:M18856.1 gb:M22246.1 gb:J04127.1 gb:M28420.1 gb:NM_000103.1 NM_000103 cytochrome P450, family 19, subfamily A, polypeptide 1 CYP19A1 1588 NM_000103 /// NM_031226 /// XM_005254190 /// XM_005254191 /// XM_005254192 /// XM_006720406 0006694 // steroid biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from direct assay 203476_at NM_006670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006670.1 /DEF=Homo sapiens 5T4 oncofetal trophoblast glycoprotein (5T4), mRNA. /FEA=mRNA /GEN=5T4 /PROD=5T4 oncofetal trophoblast glycoprotein /DB_XREF=gi:5729717 /UG=Hs.82128 5T4 oncofetal trophoblast glycoprotein /FL=gb:NM_006670.1 NM_006670 trophoblast glycoprotein TPBG 7162 NM_001166392 /// NM_006670 /// XM_005248763 0007155 // cell adhesion // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203477_at NM_001855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001855.1 /DEF=Homo sapiens collagen, type XV, alpha 1 (COL15A1), mRNA. /FEA=mRNA /GEN=COL15A1 /PROD=collagen, type XV, alpha 1 /DB_XREF=gi:4502940 /UG=Hs.83164 collagen, type XV, alpha 1 /FL=gb:NM_001855.1 gb:L25286.1 NM_001855 collagen, type XV, alpha 1 COL15A1 1306 NM_001855 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred by curator /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005582 // collagen type XV trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred by curator 203478_at NM_002494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002494.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 (6kD, KFYI) (NDUFC1), mRNA. /FEA=mRNA /GEN=NDUFC1 /PROD=NADH dehydrogenase (ubiquinone) 1, subcomplexunknown, 1 (6kD, KFYI) /DB_XREF=gi:4505366 /UG=Hs.84549 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 (6kD, KFYI) /FL=gb:AF047184.1 gb:AF047435.1 gb:NM_002494.1 NM_002494 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa NDUFC1 4717 NM_001184986 /// NM_001184987 /// NM_001184988 /// NM_001184989 /// NM_001184990 /// NM_001184991 /// NM_002494 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203479_s_at T79216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T79216 /FEA=EST /DB_XREF=gi:697725 /DB_XREF=est:yd70h03.s1 /CLONE=IMAGE:113621 /UG=Hs.89519 KIAA1046 protein /FL=gb:AB028969.1 gb:NM_014928.1 T79216 OTU deubiquitinase 4 OTUD4 54726 NM_001102653 /// NM_017493 /// NM_199324 /// XM_005263079 /// XM_005263080 /// XM_005263081 0006508 // proteolysis // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203480_s_at NM_014928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014928.1 /DEF=Homo sapiens KIAA1046 protein (KIAA1046), mRNA. /FEA=mRNA /GEN=KIAA1046 /PROD=KIAA1046 protein /DB_XREF=gi:7662459 /UG=Hs.89519 KIAA1046 protein /FL=gb:AB028969.1 gb:NM_014928.1 NM_014928 OTU deubiquitinase 4 OTUD4 54726 NM_001102653 /// NM_017493 /// NM_199324 /// XM_005263079 /// XM_005263080 /// XM_005263081 0006508 // proteolysis // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203481_at AI655902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655902 /FEA=EST /DB_XREF=gi:4739881 /DB_XREF=est:tt41c06.x1 /CLONE=IMAGE:2243338 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1 AI655902 family with sequence similarity 178, member A FAM178A 55719 NM_001136123 /// NM_001243770 /// NM_018121 /// NM_144592 /// XM_005269965 /// XM_006717913 0000785 // chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 203482_at AL133215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133215 /DEF=Human DNA sequence from clone RP11-108L7 on chromosome 10. contains part of the gene for a novel Insulin-like growth factor binding type protein with Kazal-type serine protease inhibitor domain, the gene for a novel protein similar to rat tricarbo... /FEA=mRNA_4 /DB_XREF=gi:7228177 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1 AL133215 family with sequence similarity 178, member A FAM178A 55719 NM_001136123 /// NM_001243770 /// NM_018121 /// NM_144592 /// XM_005269965 /// XM_006717913 0000785 // chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 203483_at NM_018121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_018121.1 /DEF=Homo sapiens hypothetical protein FLJ10512 (FLJ10512), mRNA. /FEA=mRNA /GEN=FLJ10512 /PROD=hypothetical protein FLJ10512 /DB_XREF=gi:8922480 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1 NM_018121 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G SEMA4G 57715 NM_001203244 /// NM_017893 /// XM_005270008 /// XM_005270009 /// XM_005270010 /// XR_246101 /// XR_428710 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203484_at NM_014302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014302.1 /DEF=Homo sapiens Sec61 gamma (SEC61G), mRNA. /FEA=mRNA /GEN=SEC61G /PROD=Sec61 gamma /DB_XREF=gi:7657545 /UG=Hs.9950 Sec61 gamma /FL=gb:AF054184.1 gb:NM_014302.1 NM_014302 Sec61 gamma subunit SEC61G 23480 NM_001012456 /// NM_014302 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006412 // translation // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from sequence or structural similarity /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203485_at NM_021136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021136.1 /DEF=Homo sapiens reticulon 1 (RTN1), mRNA. /FEA=mRNA /GEN=RTN1 /PROD=reticulon 1 /DB_XREF=gi:10863934 /UG=Hs.99947 reticulon 1 /FL=gb:NM_021136.1 gb:L10333.1 gb:L10334.1 NM_021136 reticulon 1 RTN1 6252 NM_001243115 /// NM_021136 /// NM_206852 /// NM_206857 0007165 // signal transduction // non-traceable author statement /// 0030182 // neuron differentiation // inferred from expression pattern 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203486_s_at BF195973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195973 /FEA=EST /DB_XREF=gi:11083411 /DB_XREF=est:7o88c12.x1 /CLONE=IMAGE:3643391 /UG=Hs.102708 DKFZP434A043 protein /FL=gb:NM_015396.1 BF195973 armadillo repeat containing 8 ARMC8 25852 NM_001267041 /// NM_001267042 /// NM_001282342 /// NM_014154 /// NM_015396 /// NM_213654 /// XM_006713564 /// XM_006713565 /// XM_006713566 /// XM_006713567 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203487_s_at NM_015396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015396.1 /DEF=Homo sapiens DKFZP434A043 protein (DKFZP434A043), mRNA. /FEA=mRNA /GEN=DKFZP434A043 /PROD=DKFZP434A043 protein /DB_XREF=gi:7661561 /UG=Hs.102708 DKFZP434A043 protein /FL=gb:NM_015396.1 NM_015396 armadillo repeat containing 8 ARMC8 25852 NM_001267041 /// NM_001267042 /// NM_001282342 /// NM_014154 /// NM_015396 /// NM_213654 /// XM_006713564 /// XM_006713565 /// XM_006713566 /// XM_006713567 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203488_at NM_014921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014921.1 /DEF=Homo sapiens lectomedin-2 (KIAA0821), mRNA. /FEA=mRNA /GEN=KIAA0821 /PROD=lectomedin-2 /DB_XREF=gi:7662323 /UG=Hs.107054 lectomedin-2 /FL=gb:AF307079.1 gb:AB020628.1 gb:NM_014921.1 NM_014921 latrophilin 1 LPHN1 22859 NM_001008701 /// NM_014921 /// XM_005259818 /// XM_005259819 /// XM_006722688 /// XM_006722689 /// XM_006722690 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016524 // latrotoxin receptor activity // inferred from sequence or structural similarity /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 203489_at NM_006427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006427.2 /DEF=Homo sapiens CD27-binding (Siva) protein (SIVA), transcript variant 1, mRNA. /FEA=mRNA /GEN=SIVA /PROD=CD27-binding (Siva) protein isoform 1 /DB_XREF=gi:11277467 /UG=Hs.112058 CD27-binding (Siva) protein /FL=gb:NM_006427.2 gb:U82938.1 NM_006427 SIVA1, apoptosis-inducing factor SIVA1 10572 NM_006427 /// NM_021709 0006915 // apoptotic process // inferred from electronic annotation /// 0006924 // activation-induced cell death of T cells // inferred from direct assay /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001618 // virus receptor activity // inferred from sequence or structural similarity /// 0005175 // CD27 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203490_at NM_001421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001421.1 /DEF=Homo sapiens E74-like factor 4 (ets domain transcription factor) (ELF4), mRNA. /FEA=mRNA /GEN=ELF4 /PROD=E74-like factor 4 (ets domain transcriptionfactor) /DB_XREF=gi:4503554 /UG=Hs.151139 E74-like factor 4 (ets domain transcription factor) /FL=gb:U32645.1 gb:AF000670.1 gb:NM_001421.1 NM_001421 E74-like factor 4 (ets domain transcription factor) ELF4 2000 NM_001127197 /// NM_001421 /// XM_005262389 0001787 // natural killer cell proliferation // inferred from sequence or structural similarity /// 0001866 // NK T cell proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203491_s_at AI123527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123527 /FEA=EST /DB_XREF=gi:3539293 /DB_XREF=est:qa49e12.x1 /CLONE=IMAGE:1690126 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AI123527 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203492_x_at AA918224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA918224 /FEA=EST /DB_XREF=gi:3058114 /DB_XREF=est:on82h06.s1 /CLONE=IMAGE:1563227 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AA918224 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203493_s_at AL525206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL525206 /FEA=EST /DB_XREF=gi:12788699 /DB_XREF=est:AL525206 /CLONE=CS0DC005YH06 (5 prime) /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AL525206 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203494_s_at NM_014679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014679.1 /DEF=Homo sapiens KIAA0092 gene product (KIAA0092), mRNA. /FEA=mRNA /GEN=KIAA0092 /PROD=KIAA0092 gene product /DB_XREF=gi:7661899 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 NM_014679 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203495_at NM_014665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014665.1 /DEF=Homo sapiens KIAA0014 gene product (KIAA0014), mRNA. /FEA=mRNA /GEN=KIAA0014 /PROD=KIAA0014 gene product /DB_XREF=gi:7661859 /UG=Hs.155650 KIAA0014 gene product /FL=gb:D25216.1 gb:NM_014665.1 NM_014665 leucine rich repeat containing 14 LRRC14 9684 NM_001272036 /// NM_014665 /// XM_005272358 /// XM_005272359 /// XM_005272360 /// XM_005272361 /// XM_006716688 /// XM_006716689 203496_s_at AF055994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF055994.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein complex component TRAP220 mRNA, complete cds. /FEA=mRNA /PROD=thyroid hormone receptor-associated proteincomplex component TRAP220 /DB_XREF=gi:3319289 /UG=Hs.15589 PPAR binding protein /FL=gb:AF055994.1 gb:NM_004774.1 gb:AF283812.1 AF055994 mediator complex subunit 1 MED1 5469 NM_004774 /// XM_005257465 /// XM_006721957 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002154 // thyroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003406 // retinal pigment epithelium development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from sequence or structural similarity /// 0048822 // enucleate erythrocyte development // inferred from electronic annotation /// 0051726 // regulation of cell cycle // non-traceable author statement /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from mutant phenotype /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from direct assay /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0030375 // thyroid hormone receptor coactivator activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0042809 // vitamin D receptor binding // traceable author statement /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050693 // LBD domain binding // inferred from physical interaction 203497_at NM_004774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004774.1 /DEF=Homo sapiens PPAR binding protein (PPARBP), mRNA. /FEA=mRNA /GEN=PPARBP /PROD=thyroid hormone receptor interactor 2 /DB_XREF=gi:4759265 /UG=Hs.15589 PPAR binding protein /FL=gb:AF055994.1 gb:NM_004774.1 gb:AF283812.1 NM_004774 mediator complex subunit 1 MED1 5469 NM_004774 /// XM_005257465 /// XM_006721957 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002154 // thyroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003406 // retinal pigment epithelium development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from sequence or structural similarity /// 0048822 // enucleate erythrocyte development // inferred from electronic annotation /// 0051726 // regulation of cell cycle // non-traceable author statement /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from mutant phenotype /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from direct assay /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0030375 // thyroid hormone receptor coactivator activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0042809 // vitamin D receptor binding // traceable author statement /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050693 // LBD domain binding // inferred from physical interaction 203498_at NM_005822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005822.1 /DEF=Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA. /FEA=mRNA /GEN=DSCR1L1 /PROD=Down syndrome critical region gene 1-like 1protein /DB_XREF=gi:5032234 /UG=Hs.156007 Down syndrome critical region gene 1-like 1 /FL=gb:D83407.1 gb:NM_005822.1 NM_005822 regulator of calcineurin 2 RCAN2 10231 NM_001251973 /// NM_001251974 /// NM_005822 /// XM_006714948 0007417 // central nervous system development // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // non-traceable author statement 203499_at NM_004431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004431.1 /DEF=Homo sapiens EphA2 (EPHA2), mRNA. /FEA=mRNA /GEN=EPHA2 /PROD=EphA2 /DB_XREF=gi:4758277 /UG=Hs.171596 EphA2 /FL=gb:M59371.1 gb:NM_004431.1 NM_004431 EPH receptor A2 EPHA2 1969 NM_004431 /// XM_005245751 /// XM_005245752 0001501 // skeletal system development // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010591 // regulation of lamellipodium assembly // inferred from mutant phenotype /// 0014028 // notochord formation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0046849 // bone remodeling // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048320 // axial mesoderm formation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060035 // notochord cell development // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from sequence or structural similarity /// 0070309 // lens fiber cell morphogenesis // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203500_at NM_000159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000159.1 /DEF=Homo sapiens glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. /FEA=mRNA /GEN=GCDH /PROD=glutaryl-Coenzyme A dehydrogenase isoform a /DB_XREF=gi:4503942 /UG=Hs.184141 glutaryl-Coenzyme A dehydrogenase /FL=gb:BC002579.1 gb:U69141.1 gb:NM_000159.1 NM_000159 glutaryl-CoA dehydrogenase GCDH 2639 NM_000159 /// NM_013976 /// NR_102316 /// NR_102317 /// XM_006722720 /// XM_006722721 0006554 // lysine catabolic process // traceable author statement /// 0006568 // tryptophan metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004361 // glutaryl-CoA dehydrogenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 203501_at NM_006102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006102.1 /DEF=Homo sapiens plasma glutamate carboxypeptidase (PGCP), mRNA. /FEA=mRNA /GEN=PGCP /PROD=plasma glutamate carboxypeptidase /DB_XREF=gi:5174626 /UG=Hs.197335 plasma glutamate carboxypeptidase /FL=gb:AF119386.1 gb:NM_006102.1 NM_006102 carboxypeptidase Q CPQ 10404 NM_016134 /// XM_005250755 /// XM_006716498 /// XR_428374 0006508 // proteolysis // inferred from direct assay /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0043171 // peptide catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070573 // metallodipeptidase activity // inferred from direct assay 203502_at NM_001724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001724.1 /DEF=Homo sapiens 2,3-bisphosphoglycerate mutase (BPGM), mRNA. /FEA=mRNA /GEN=BPGM /PROD=2,3-bisphosphoglycerate mutase /DB_XREF=gi:4502444 /UG=Hs.198365 2,3-bisphosphoglycerate mutase /FL=gb:NM_001724.1 NM_001724 2,3-bisphosphoglycerate mutase BPGM 669 NM_001293085 /// NM_001724 /// NM_199186 /// XM_006716096 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation 203503_s_at NM_004565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004565.1 /DEF=Homo sapiens peroxisomal biogenesis factor 14 (PEX14), mRNA. /FEA=mRNA /GEN=PEX14 /PROD=peroxisomal biogenesis factor 14 /DB_XREF=gi:4758895 /UG=Hs.19851 peroxisomal biogenesis factor 14 /FL=gb:AF045186.1 gb:AB017546.1 gb:NM_004565.1 NM_004565 peroxisomal biogenesis factor 14 PEX14 5195 NM_004565 /// XM_005263470 /// XM_006710685 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from genetic interaction /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016560 // protein import into peroxisome matrix, docking // inferred from electronic annotation /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from direct assay /// 0036250 // peroxisome transport along microtubule // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0044721 // protein import into peroxisome matrix, substrate release // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from physical interaction 203504_s_at NM_005502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005502.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), mRNA. /FEA=mRNA /GEN=ABCA1 /PROD=ATP-binding cassette, sub-family A member 1 /DB_XREF=gi:5915657 /UG=Hs.211562 ATP-binding cassette, sub-family A (ABC1), member 1 /FL=gb:AF165281.1 gb:NM_005502.1 gb:AF285167.1 NM_005502 ATP-binding cassette, sub-family A (ABC1), member 1 ABCA1 19 NM_005502 /// XM_005251773 /// XM_005251774 /// XM_005251776 /// XM_005251778 /// XM_005251780 /// XM_006716995 0002790 // peptide secretion // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0060155 // platelet dense granule organization // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008509 // anion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0019905 // syntaxin binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 203505_at AF285167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF285167.1 /DEF=Homo sapiens ATP-binding cassette transporter 1 (ABCA1) mRNA, complete cds. /FEA=mRNA /GEN=ABCA1 /PROD=ATP-binding cassette transporter 1 /DB_XREF=gi:9755158 /UG=Hs.211562 ATP-binding cassette, sub-family A (ABC1), member 1 /FL=gb:AF165281.1 gb:NM_005502.1 gb:AF285167.1 AF285167 ATP-binding cassette, sub-family A (ABC1), member 1 ABCA1 19 NM_005502 /// XM_005251773 /// XM_005251774 /// XM_005251776 /// XM_005251778 /// XM_005251780 /// XM_006716995 0002790 // peptide secretion // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0060155 // platelet dense granule organization // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008509 // anion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0019905 // syntaxin binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 203506_s_at NM_005120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005120.1 /DEF=Homo sapiens trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) (TNRC11), mRNA. /FEA=mRNA /GEN=TNRC11 /PROD=trinucleotide repeat containing 11(THR-associated protein, 230 kDa subunit) /DB_XREF=gi:4827041 /UG=Hs.211607 trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) /FL=gb:U80742.1 gb:AF071309.1 gb:AF117755.1 gb:NM_005120.1 NM_005120 mediator complex subunit 12 MED12 9968 NM_005120 /// XM_005262317 /// XM_005262319 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090245 // axis elongation involved in somitogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 203507_at NM_001251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001251.1 /DEF=Homo sapiens CD68 antigen (CD68), mRNA. /FEA=mRNA /GEN=CD68 /PROD=CD68 antigen /DB_XREF=gi:4557434 /UG=Hs.246381 CD68 antigen /FL=gb:NM_001251.1 NM_001251 CD68 molecule /// uncharacterized LOC101928634 /// small nucleolar RNA, H/ACA box 67 CD68 /// LOC101928634 /// SNORA67 968 /// 26781 /// 101928634 NM_001040059 /// NM_001251 /// NR_002912 /// XR_244579 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203508_at NM_001066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001066.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), mRNA. /FEA=mRNA /GEN=TNFRSF1B /PROD=tumor necrosis factor receptor 2 (75kD) /DB_XREF=gi:4507576 /UG=Hs.256278 tumor necrosis factor receptor superfamily, member 1B /FL=gb:M32315.1 gb:M55994.1 gb:NM_001066.1 NM_001066 tumor necrosis factor receptor superfamily, member 1B TNFRSF1B 7133 NM_001066 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043196 // varicosity // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005031 // tumor necrosis factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203509_at NM_003105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003105.2 /DEF=Homo sapiens sortilin-related receptor, L(DLR class) A repeats-containing (SORL1), mRNA. /FEA=mRNA /GEN=SORL1 /PROD=sortilin-related receptor, L(DLR class) Arepeats-containing /DB_XREF=gi:6325473 /UG=Hs.278571 sortilin-related receptor, L(DLR class) A repeats-containing /FL=gb:U60975.2 gb:NM_003105.2 NM_003105 sortilin-related receptor, L(DLR class) A repeats containing SORL1 6653 NM_003105 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006622 // protein targeting to lysosome // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032460 // negative regulation of protein oligomerization // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045053 // protein retention in Golgi apparatus // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from direct assay /// 0070863 // positive regulation of protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from sequence or structural similarity /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902771 // positive regulation of choline O-acetyltransferase activity // inferred from sequence or structural similarity /// 1902948 // negative regulation of tau-protein kinase activity // inferred from sequence or structural similarity /// 1902953 // positive regulation of ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 1902955 // positive regulation of early endosome to recycling endosome transport // inferred from mutant phenotype /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from direct assay /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902966 // positive regulation of protein localization to early endosome // inferred from mutant phenotype /// 1902997 // negative regulation of neurofibrillary tangle assembly // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction 203510_at BG170541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG170541 /FEA=EST /DB_XREF=gi:12677244 /DB_XREF=est:602322942F1 /CLONE=IMAGE:4425947 /UG=Hs.285754 met proto-oncogene (hepatocyte growth factor receptor) /FL=gb:J02958.1 gb:NM_000245.1 BG170541 MET proto-oncogene, receptor tyrosine kinase MET 4233 NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 203511_s_at AF041432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF041432.1 /DEF=Homo sapiens bet3 (BET3) mRNA, complete cds. /FEA=mRNA /GEN=BET3 /PROD=bet3 /DB_XREF=gi:2791803 /UG=Hs.288013 similar to yeast BET3 (S. cerevisiae) /FL=gb:AF041432.1 gb:NM_014408.1 AF041432 trafficking protein particle complex 3 TRAPPC3 27095 NM_001270894 /// NM_001270895 /// NM_001270896 /// NM_001270897 /// NM_014408 /// NR_073097 /// NR_073098 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0030008 // TRAPP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203512_at NM_014408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014408.1 /DEF=Homo sapiens similar to yeast BET3 (S. cerevisiae) (BET3), mRNA. /FEA=mRNA /GEN=BET3 /PROD=similar to yeast BET3 (S. cerevisiae) /DB_XREF=gi:7656925 /UG=Hs.288013 similar to yeast BET3 (S. cerevisiae) /FL=gb:AF041432.1 gb:NM_014408.1 NM_014408 trafficking protein particle complex 3 TRAPPC3 27095 NM_001270894 /// NM_001270895 /// NM_001270896 /// NM_001270897 /// NM_014408 /// NR_073097 /// NR_073098 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0030008 // TRAPP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203513_at NM_025137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025137.1 /DEF=Homo sapiens hypothetical protein FLJ21439 (FLJ21439), mRNA. /FEA=mRNA /GEN=FLJ21439 /PROD=hypothetical protein FLJ21439 /DB_XREF=gi:13376718 /UG=Hs.288872 hypothetical protein FLJ21439 /FL=gb:NM_025137.1 NM_025137 spastic paraplegia 11 (autosomal recessive) SPG11 80208 NM_001160227 /// NM_025137 /// XM_005254694 /// XM_005254695 /// XM_006720699 /// XM_006720700 /// XM_006720701 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203514_at BF971923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF971923 /FEA=EST /DB_XREF=gi:12339138 /DB_XREF=est:602240326F1 /CLONE=IMAGE:4328791 /UG=Hs.29282 mitogen-activated protein kinase kinase kinase 3 /FL=gb:U78876.1 gb:NM_002401.1 BF971923 mitogen-activated protein kinase kinase kinase 3 MAP3K3 4215 NM_002401 /// NM_203351 /// XM_005257376 /// XM_005257377 /// XM_005257378 /// XM_006721909 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0046777 // protein autophosphorylation // inferred from direct assay 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203515_s_at NM_006556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006556.1 /DEF=Homo sapiens phosphomevalonate kinase (PMVK), mRNA. /FEA=mRNA /GEN=PMVK /PROD=phosphomevalonate kinase /DB_XREF=gi:5729979 /UG=Hs.30954 phosphomevalonate kinase /FL=gb:L77213.1 gb:NM_006556.1 NM_006556 phosphomevalonate kinase PMVK 10654 NM_006556 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070723 // response to cholesterol // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004631 // phosphomevalonate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203516_at NM_003098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003098.1 /DEF=Homo sapiens syntrophin, alpha 1(dystrophin-associated protein A1, 59kD, acidic component) (SNTA1), mRNA. /FEA=mRNA /GEN=SNTA1 /PROD=syntrophin, alpha 1(dystrophin-associatedprotein A1, 59kD, acidic component) /DB_XREF=gi:4507136 /UG=Hs.31121 syntrophin, alpha 1(dystrophin-associated protein A1, 59kD, acidic component) /FL=gb:U40571.1 gb:NM_003098.1 NM_003098 syntrophin, alpha 1 SNTA1 6640 NM_003098 /// XM_005260517 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003117 // regulation of vasoconstriction by circulating norepinephrine // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from mutant phenotype /// 1902305 // regulation of sodium ion transmembrane transport // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 203517_at NM_006554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006554.1 /DEF=Homo sapiens metaxin 2 (MTX2), mRNA. /FEA=mRNA /GEN=MTX2 /PROD=metaxin 2 /DB_XREF=gi:5729936 /UG=Hs.31584 metaxin 2 /FL=gb:AF053551.1 gb:NM_006554.1 NM_006554 metaxin 2 MTX2 10651 NM_001006635 /// NM_006554 /// NR_027850 /// XM_006712199 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 203518_at NM_000081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000081.1 /DEF=Homo sapiens Chediak-Higashi syndrome 1 (CHS1), mRNA. /FEA=mRNA /GEN=CHS1 /PROD=beige protein homolog /DB_XREF=gi:4502838 /UG=Hs.36508 Chediak-Higashi syndrome 1 /FL=gb:U67615.1 gb:NM_000081.1 NM_000081 lysosomal trafficking regulator LYST 1130 NM_000081 /// NM_001005736 /// NR_102436 /// XM_005273027 /// XM_005273028 /// XM_005273029 /// XM_005273030 /// XM_006711731 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from sequence or structural similarity /// 0032438 // melanosome organization // inferred from sequence or structural similarity /// 0032510 // endosome to lysosome transport via multivesicular body sorting pathway // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203519_s_at NM_015542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015542.1 /DEF=Homo sapiens regulator of nonsense transcripts 2; DKFZP434D222 protein (RENT2), mRNA. /FEA=mRNA /GEN=RENT2 /PROD=regulator of nonsense transcripts 2 /DB_XREF=gi:11693131 /UG=Hs.3862 regulator of nonsense transcripts 2; DKFZP434D222 protein /FL=gb:AF301013.1 gb:NM_015542.1 gb:AY013249.1 gb:AF318574.1 NM_015542 UPF2 regulator of nonsense transcripts homolog (yeast) UPF2 26019 NM_015542 /// NM_080599 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203520_s_at AW613549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW613549 /FEA=EST /DB_XREF=gi:7318735 /DB_XREF=est:hh33g04.x1 /CLONE=IMAGE:2956950 /UG=Hs.48433 endocrine regulator /FL=gb:AF121141.1 gb:NM_014345.1 AW613549 zinc finger protein 318 ZNF318 24149 NM_014345 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203521_s_at NM_014345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014345.1 /DEF=Homo sapiens endocrine regulator (HRIHFB2436), mRNA. /FEA=mRNA /GEN=HRIHFB2436 /PROD=endocrine regulator /DB_XREF=gi:7657183 /UG=Hs.48433 endocrine regulator /FL=gb:AF121141.1 gb:NM_014345.1 NM_014345 zinc finger protein 318 ZNF318 24149 NM_014345 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203522_at NM_005125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005125.1 /DEF=Homo sapiens copper chaperone for superoxide dismutase (CCS), mRNA. /FEA=mRNA /GEN=CCS /PROD=copper chaperone for superoxide dismutase /DB_XREF=gi:4826664 /UG=Hs.5002 copper chaperone for superoxide dismutase /FL=gb:AF002210.1 gb:NM_005125.1 NM_005125 copper chaperone for superoxide dismutase CCS 9973 NM_005125 /// XR_247219 0006801 // superoxide metabolic process // traceable author statement /// 0015680 // intracellular copper ion transport // traceable author statement /// 0019430 // removal of superoxide radicals // not recorded /// 0030001 // metal ion transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // traceable author statement /// 0051353 // positive regulation of oxidoreductase activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // /// 0005829 // cytosol // traceable author statement 0004784 // superoxide dismutase activity // not recorded /// 0005375 // copper ion transmembrane transporter activity // traceable author statement /// 0005507 // copper ion binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // not recorded /// 0015035 // protein disulfide oxidoreductase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016532 // superoxide dismutase copper chaperone activity // /// 0046872 // metal ion binding // inferred from electronic annotation 203523_at NM_002339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002339.1 /DEF=Homo sapiens lymphocyte-specific protein 1 (LSP1), mRNA. /FEA=mRNA /GEN=LSP1 /PROD=lymphocyte-specific protein 1 /DB_XREF=gi:10880978 /UG=Hs.56729 lymphocyte-specific protein 1 /FL=gb:NM_002339.1 gb:BC001785.1 gb:M33552.1 NM_002339 lymphocyte-specific protein 1 LSP1 4046 NM_001013253 /// NM_001013254 /// NM_001013255 /// NM_001242932 /// NM_001289005 /// NM_002339 /// XM_005252924 /// XM_005252926 /// XM_005252927 /// XM_006718232 0006928 // cellular component movement // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 203524_s_at NM_021126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021126.1 /DEF=Homo sapiens mercaptopyruvate sulfurtransferase (MPST), mRNA. /FEA=mRNA /GEN=MPST /PROD=mercaptopyruvate sulfurtransferase /DB_XREF=gi:13489090 /UG=Hs.74097 mercaptopyruvate sulfurtransferase /FL=gb:NM_021126.1 NM_021126 mercaptopyruvate sulfurtransferase MPST 4357 NM_001013436 /// NM_001013440 /// NM_001130517 /// NM_021126 /// NR_024038 /// XM_005261610 /// XM_006724253 0008152 // metabolic process // inferred from electronic annotation /// 0009440 // cyanate catabolic process // traceable author statement /// 0009636 // response to toxic substance // traceable author statement /// 0070814 // hydrogen sulfide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004792 // thiosulfate sulfurtransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016784 // 3-mercaptopyruvate sulfurtransferase activity // inferred from electronic annotation 203525_s_at AI375486 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375486 /FEA=EST /DB_XREF=gi:4175476 /DB_XREF=est:tc30f12.x1 /CLONE=IMAGE:2066159 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1 AI375486 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203526_s_at M74088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74088.1 /DEF=Human APC gene mRNA, complete cds. /FEA=mRNA /GEN=APC /DB_XREF=gi:182396 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1 M74088 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203527_s_at NM_000038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000038.1 /DEF=Homo sapiens adenomatosis polyposis coli (APC), mRNA. /FEA=mRNA /GEN=APC /PROD=adenomatosis polyposis coli /DB_XREF=gi:4557318 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1 NM_000038 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203528_at NM_006378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006378.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), mRNA. /FEA=mRNA /GEN=SEMA4D /PROD=sema domain, immunoglobulin domain (Ig),transmembrane domain (TM) and short cytoplasmic domain,(semaphorin) 4D /DB_XREF=gi:5454049 /UG=Hs.79089 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D /FL=gb:U60800.1 gb:NM_006378.1 NM_006378 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D SEMA4D 10507 NM_001142287 /// NM_006378 /// NM_182635 /// XM_005251654 /// XM_006716922 /// XM_006716923 /// XM_006716924 /// XM_006716925 /// XM_006716926 /// XM_006716927 /// XM_006716928 /// XM_006716929 /// XM_006716930 /// XM_006716931 /// XR_242561 /// XR_242562 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031344 // regulation of cell projection organization // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043931 // ossification involved in bone maturation // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0048672 // positive regulation of collateral sprouting // inferred from mutant phenotype /// 0048814 // regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0070486 // leukocyte aggregation // inferred from mutant phenotype /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from mutant phenotype /// 1900220 // semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from sequence or structural similarity 203529_at NM_016294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016294.1 /DEF=Homo sapiens serinethreonine protein phosphatase catalytic subunit (LOC51723), mRNA. /FEA=mRNA /GEN=LOC51723 /PROD=serinethreonine protein phosphatase catalyticsubunit /DB_XREF=gi:7706488 /UG=Hs.80324 serinethreonine protein phosphatase catalytic subunit /FL=gb:AF035158.2 gb:NM_016294.1 NM_016294 protein phosphatase 6, catalytic subunit PPP6C 5537 NM_001123355 /// NM_001123369 /// NM_002721 /// XM_006717175 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203530_s_at NM_004604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004604.1 /DEF=Homo sapiens syntaxin 4A (placental) (STX4A), mRNA. /FEA=mRNA /GEN=STX4A /PROD=syntaxin 4A (placental) /DB_XREF=gi:4759185 /UG=Hs.83734 syntaxin 4A (placental) /FL=gb:BC002436.1 gb:AF026007.1 gb:U07158.1 gb:NM_004604.1 NM_004604 syntaxin 4 STX4 6810 NM_001272095 /// NM_001272096 /// NM_004604 /// XM_005255521 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005773 // vacuole // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0043219 // lateral loop // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203531_at BF435809 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF435809 /FEA=EST /DB_XREF=gi:11448124 /DB_XREF=est:nab42a09.x1 /CLONE=IMAGE:3268504 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1 BF435809 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203532_x_at AF017061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF017061.1 /DEF=Homo sapiens vasopressin-activated calcium mobilizing putative receptor protein (VACM-1) mRNA, complete cds. /FEA=mRNA /GEN=VACM-1 /PROD=vasopressin-activated calcium mobilizingputative receptor protein /DB_XREF=gi:2394273 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1 AF017061 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203533_s_at NM_003478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003478.1 /DEF=Homo sapiens cullin 5 (CUL5), mRNA. /FEA=mRNA /GEN=CUL5 /PROD=Vasopressin-activated calcium-mobilizingreceptor-1 /DB_XREF=gi:4503166 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1 NM_003478 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203534_at NM_014462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014462.1 /DEF=Homo sapiens Lsm1 protein (LSM1), mRNA. /FEA=mRNA /GEN=LSM1 /PROD=Lsm1 protein /DB_XREF=gi:7657312 /UG=Hs.111783 Lsm1 protein /FL=gb:BC001767.1 gb:AF000177.1 gb:NM_014462.1 NM_014462 LSM1, U6 small nuclear RNA associated LSM1 27257 NM_014462 /// NR_045492 /// NR_045493 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203535_at NM_002965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002965.2 /DEF=Homo sapiens S100 calcium-binding protein A9 (calgranulin B) (S100A9), mRNA. /FEA=mRNA /GEN=S100A9 /PROD=S100 calcium-binding protein A9 /DB_XREF=gi:9845520 /UG=Hs.112405 S100 calcium-binding protein A9 (calgranulin B) /FL=gb:M26311.1 gb:NM_002965.2 NM_002965 S100 calcium binding protein A9 S100A9 6280 NM_002965 0001816 // cytokine production // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from direct assay /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006914 // autophagy // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0032119 // sequestering of zinc ion // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032602 // chemokine production // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045113 // regulation of integrin biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0070488 // neutrophil aggregation // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0035662 // Toll-like receptor 4 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // traceable author statement /// 0050786 // RAGE receptor binding // traceable author statement 203536_s_at NM_004804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004804.1 /DEF=Homo sapiens WD40 protein Ciao1 (CIAO1), mRNA. /FEA=mRNA /GEN=CIAO1 /PROD=WD40 protein Ciao1 /DB_XREF=gi:4757987 /UG=Hs.12109 WD40 protein Ciao1 /FL=gb:BC001395.1 gb:U63810.1 gb:NM_004804.1 NM_004804 cytosolic iron-sulfur assembly component 1 CIAO1 9391 NM_004804 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016226 // iron-sulfur cluster assembly // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203537_at NM_002767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002767.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPSAP2), mRNA. /FEA=mRNA /GEN=PRPSAP2 /PROD=phosphoribosyl pyrophosphatesynthetase-associated protein 2 /DB_XREF=gi:4506132 /UG=Hs.13339 phosphoribosyl pyrophosphate synthetase-associated protein 2 /FL=gb:AB007851.1 gb:NM_002767.1 NM_002767 phosphoribosyl pyrophosphate synthetase-associated protein 2 PRPSAP2 5636 NM_001243936 /// NM_001243940 /// NM_001243941 /// NM_001243942 /// NM_002767 /// XM_005256724 /// XM_005256725 /// XM_005256726 /// XM_005256727 /// XM_005256729 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement 203538_at NM_001745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001745.1 /DEF=Homo sapiens calcium modulating ligand (CAMLG), mRNA. /FEA=mRNA /GEN=CAMLG /PROD=calcium modulating ligand /DB_XREF=gi:4502558 /UG=Hs.13572 calcium modulating ligand /FL=gb:NM_001745.1 gb:U18242.1 NM_001745 calcium modulating ligand CAMLG 819 NM_001745 0001881 // receptor recycling // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 203539_s_at J04569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J04569.1 /DEF=Human glial fibrillary acidic protein (GFAP) mRNA, complete cds. /FEA=mRNA /GEN=GFAP /DB_XREF=gi:183074 /UG=Hs.1447 glial fibrillary acidic protein /FL=gb:J04569.1 gb:NM_002055.1 J04569 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203540_at NM_002055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002055.1 /DEF=Homo sapiens glial fibrillary acidic protein (GFAP), mRNA. /FEA=mRNA /GEN=GFAP /PROD=glial fibrillary acidic protein /DB_XREF=gi:4503978 /UG=Hs.1447 glial fibrillary acidic protein /FL=gb:J04569.1 gb:NM_002055.1 NM_002055 glial fibrillary acidic protein GFAP 2670 NM_001131019 /// NM_001242376 /// NM_002055 0009611 // response to wounding // inferred from electronic annotation /// 0010625 // positive regulation of Schwann cell proliferation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0045103 // intermediate filament-based process // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0051580 // regulation of neurotransmitter uptake // inferred from electronic annotation /// 0060020 // Bergmann glial cell differentiation // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0097449 // astrocyte projection // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation 203541_s_at BF438302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF438302 /FEA=EST /DB_XREF=gi:11450819 /DB_XREF=est:7q07f04.x1 /CLONE=IMAGE:3676950 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1 BF438302 Kruppel-like factor 9 KLF9 687 NM_001206 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203542_s_at AI690205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI690205 /FEA=EST /DB_XREF=gi:4901499 /DB_XREF=est:tx33d02.x1 /CLONE=IMAGE:2271363 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1 AI690205 Kruppel-like factor 9 KLF9 687 NM_001206 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203543_s_at NM_001206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001206.1 /DEF=Homo sapiens basic transcription element binding protein 1 (BTEB1), mRNA. /FEA=mRNA /GEN=BTEB1 /PROD=basic transcription element binding protein 1 /DB_XREF=gi:4557374 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1 NM_001206 Kruppel-like factor 9 KLF9 687 NM_001206 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203544_s_at NM_003473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003473.1 /DEF=Homo sapiens signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (STAM), mRNA. /FEA=mRNA /GEN=STAM /PROD=signal transducing adaptor molecule (SH3 domainand ITAM motif) 1 /DB_XREF=gi:4507248 /UG=Hs.153487 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 /FL=gb:U43899.1 gb:NM_003473.1 NM_003473 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 STAM 8027 NM_003473 /// NR_037774 /// XM_005252603 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203545_at NM_024079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024079.1 /DEF=Homo sapiens hypothetical protein MGC2840 similar to a putative glucosyltransferase (MGC2840), mRNA. /FEA=mRNA /GEN=MGC2840 /PROD=hypothetical protein MGC2840 similar to aputative glucosyltransferase /DB_XREF=gi:13129069 /UG=Hs.155356 hypothetical protein MGC2840 similar to a putative glucosyltransferase /FL=gb:BC001133.1 gb:NM_024079.1 NM_024079 ALG8, alpha-1,3-glucosyltransferase ALG8 79053 NM_001007027 /// NM_001007028 /// NM_024079 /// XM_005274247 /// XR_428923 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from mutant phenotype /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000033 // alpha-1,3-mannosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 203546_at NM_014652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014652.1 /DEF=Homo sapiens KIAA0724 gene product (KIAA0724), mRNA. /FEA=mRNA /GEN=KIAA0724 /PROD=KIAA0724 gene product /DB_XREF=gi:7662265 /UG=Hs.158497 KIAA0724 gene product /FL=gb:AB018267.1 gb:NM_014652.1 gb:AF267987.1 NM_014652 importin 13 IPO13 9670 NM_014652 /// XM_003846624 0006606 // protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation 203547_at U47924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U47924 /DEF=Human chromosome 12p13 sequence /FEA=mRNA_6 /DB_XREF=gi:1633547 /UG=Hs.17483 CD4 antigen (p55) /FL=gb:NM_000616.1 gb:M12807.1 U47924 CD4 molecule CD4 920 NM_000616 /// NM_001195014 /// NM_001195015 /// NM_001195016 /// NM_001195017 /// NR_036545 0001816 // cytokine production // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006948 // induction by virus of host cell-cell fusion // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from direct assay /// 0030260 // entry into host cell // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032507 // maintenance of protein location in cell // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0045058 // T cell selection // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045234 // protein palmitoleylation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // non-traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0015026 // coreceptor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042289 // MHC class II protein binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 203548_s_at BF672975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF672975 /FEA=EST /DB_XREF=gi:11946870 /DB_XREF=est:602152854F1 /CLONE=IMAGE:4294021 /UG=Hs.180878 lipoprotein lipase /FL=gb:M15856.1 gb:NM_000237.1 BF672975 lipoprotein lipase LPL 4023 NM_000237 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred by curator /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // inferred from sequence or structural similarity /// 0007603 // phototransduction, visible light // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010886 // positive regulation of cholesterol storage // inferred from mutant phenotype /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from sequence or structural similarity /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070328 // triglyceride homeostasis // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from direct assay /// 0004465 // lipoprotein lipase activity // inferred from sequence or structural similarity /// 0004620 // phospholipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017129 // triglyceride binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction 203549_s_at NM_000237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000237.1 /DEF=Homo sapiens lipoprotein lipase (LPL), mRNA. /FEA=mRNA /GEN=LPL /PROD=lipoprotein lipase precursor /DB_XREF=gi:4557726 /UG=Hs.180878 lipoprotein lipase /FL=gb:M15856.1 gb:NM_000237.1 NM_000237 lipoprotein lipase LPL 4023 NM_000237 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred by curator /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // inferred from sequence or structural similarity /// 0007603 // phototransduction, visible light // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010886 // positive regulation of cholesterol storage // inferred from mutant phenotype /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from sequence or structural similarity /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070328 // triglyceride homeostasis // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from direct assay /// 0004465 // lipoprotein lipase activity // inferred from sequence or structural similarity /// 0004620 // phospholipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017129 // triglyceride binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction 203550_s_at NM_006589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006589.1 /DEF=Homo sapiens chromosome 1 open reading frame 2 (C1ORF2), mRNA. /FEA=mRNA /GEN=C1ORF2 /PROD=chromosome 1 open reading frame 2 /DB_XREF=gi:5729751 /UG=Hs.19554 chromosome 1 open reading frame 2 /FL=gb:NM_006589.1 NM_006589 family with sequence similarity 189, member B FAM189B 10712 NM_001267608 /// NM_006589 /// NM_198264 /// XM_005244845 /// XM_005244847 /// XM_005244848 /// XM_005276738 /// XM_005276740 /// XM_005276741 /// XM_006711126 /// XM_006711127 /// XM_006726209 /// XM_006726210 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 203551_s_at NM_004375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004375.1 /DEF=Homo sapiens COX11 (yeast) homolog, cytochrome c oxidase assembly protein (COX11), mRNA. /FEA=mRNA /GEN=COX11 /PROD=COX11 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:4758033 /UG=Hs.241515 COX11 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:AF044321.1 gb:NM_004375.1 NM_004375 cytochrome c oxidase assembly homolog 11 (yeast) COX11 1353 NM_001162861 /// NM_001162862 /// NM_004375 /// NR_027941 /// NR_027942 /// XM_006721704 /// XM_006721705 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 203552_at AW298170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW298170 /FEA=EST /DB_XREF=gi:6704806 /DB_XREF=est:UI-H-BW0-ajt-a-06-0-UI.s1 /CLONE=IMAGE:2732819 /UG=Hs.246970 mitogen-activated protein kinase kinase kinase kinase 5 /FL=gb:U77129.1 gb:NM_006575.1 AW298170 mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 11183 NM_006575 /// NM_198794 /// XM_006720013 /// XM_006720014 0000165 // MAPK cascade // /// 0000185 // activation of MAPKKK activity // /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203553_s_at NM_006575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006575.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), mRNA. /FEA=mRNA /GEN=MAP4K5 /PROD=mitogen-activated protein kinase kinase kinasekinase /DB_XREF=gi:5729890 /UG=Hs.246970 mitogen-activated protein kinase kinase kinase kinase 5 /FL=gb:U77129.1 gb:NM_006575.1 NM_006575 mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 11183 NM_006575 /// NM_198794 /// XM_006720013 /// XM_006720014 0000165 // MAPK cascade // /// 0000185 // activation of MAPKKK activity // /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203554_x_at NM_004219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004219.2 /DEF=Homo sapiens pituitary tumor-transforming 1 (PTTG1), mRNA. /FEA=mRNA /GEN=PTTG1 /PROD=pituitary tumor-transforming protein 1 /DB_XREF=gi:11038651 /UG=Hs.252587 pituitary tumor-transforming 1 /FL=gb:NM_004219.2 gb:AF095287.1 gb:AF062649.1 gb:AF075242.1 NM_004219 pituitary tumor-transforming 1 PTTG1 9232 NM_001282382 /// NM_001282383 /// NM_004219 0000278 // mitotic cell cycle // traceable author statement /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 203555_at NM_014369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014369.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), mRNA. /FEA=mRNA /GEN=PTPN18 /PROD=protein tyrosine phosphatase, non-receptor type18 (brain-derived) /DB_XREF=gi:7657483 /UG=Hs.278597 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) /FL=gb:NM_014369.1 NM_014369 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) PTPN18 26469 NM_001142370 /// NM_014369 /// XM_006712415 /// XM_006712416 /// XM_006712417 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203556_at NM_014943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014943.1 /DEF=Homo sapiens KIAA0854 protein (KIAA0854), mRNA. /FEA=mRNA /GEN=KIAA0854 /PROD=KIAA0854 protein /DB_XREF=gi:7662341 /UG=Hs.30209 KIAA0854 protein /FL=gb:AB020661.1 gb:NM_014943.1 NM_014943 zinc fingers and homeoboxes 2 ZHX2 22882 NM_014943 /// XM_005250836 /// XM_005250837 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 203557_s_at NM_000281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000281.1 /DEF=Homo sapiens 6-pyruvoyl-tetrahydropterin synthasedimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) (PCBD), mRNA. /FEA=mRNA /GEN=PCBD /PROD=pterin-4 alpha-carbinolamine dehydrataseprecursor /DB_XREF=gi:4557830 /UG=Hs.3192 6-pyruvoyl-tetrahydropterin synthasedimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) /FL=gb:NM_000281.1 gb:AF082858.1 gb:L41559.1 NM_000281 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha PCBD1 5092 NM_000281 /// NM_001289797 /// XM_005269877 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043496 // regulation of protein homodimerization activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004505 // phenylalanine 4-monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008124 // 4-alpha-hydroxytetrahydrobiopterin dehydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203558_at NM_014780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014780.1 /DEF=Homo sapiens KIAA0076 gene product (KIAA0076), mRNA. /FEA=mRNA /GEN=KIAA0076 /PROD=KIAA0076 gene product /DB_XREF=gi:7661893 /UG=Hs.51039 KIAA0076 gene product /FL=gb:D38548.1 gb:NM_014780.1 NM_014780 cullin 7 CUL7 9820 NM_001168370 /// NM_014780 /// XM_005249503 /// XM_006715285 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001890 // placenta development // inferred from direct assay /// 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from genetic interaction /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005680 // anaphase-promoting complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 1990393 // 3M complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 203559_s_at NM_001091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001091.1 /DEF=Homo sapiens amiloride binding protein 1 (amine oxidase (copper-containing)) (ABP1), mRNA. /FEA=mRNA /GEN=ABP1 /PROD=amiloride binding protein 1 precursor /DB_XREF=gi:4501850 /UG=Hs.75741 amiloride binding protein 1 (amine oxidase (copper-containing)) /FL=gb:M55602.1 gb:NM_001091.1 gb:U11862.1 NM_001091 amine oxidase, copper containing 1 AOC1 26 NM_001091 /// NM_001272072 /// XM_005249967 /// XM_006715918 0009308 // amine metabolic process // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0035874 // cellular response to copper ion starvation // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071420 // cellular response to histamine // inferred from direct assay /// 0071504 // cellular response to heparin // traceable author statement /// 0097185 // cellular response to azide // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from direct assay /// 0005261 // cation channel activity // inferred from direct assay /// 0005272 // sodium channel activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0008131 // primary amine oxidase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from direct assay /// 0052597 // diamine oxidase activity // inferred from direct assay /// 0052598 // histamine oxidase activity // inferred from electronic annotation /// 0052599 // methylputrescine oxidase activity // inferred from electronic annotation /// 0052600 // propane-1,3-diamine oxidase activity // inferred from electronic annotation 203560_at NM_003878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003878.1 /DEF=Homo sapiens gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (GGH), mRNA. /FEA=mRNA /GEN=GGH /PROD=gamma-glutamyl hydrolase (conjugase,folylpolygammaglutamyl hydrolase) precursor /DB_XREF=gi:4503986 /UG=Hs.78619 gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) /FL=gb:U55206.1 gb:NM_003878.1 NM_003878 gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) GGH 8836 NM_003878 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008238 // exopeptidase activity // traceable author statement /// 0008242 // omega peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034722 // gamma-glutamyl-peptidase activity // inferred from direct assay 203561_at NM_021642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021642.1 /DEF=Homo sapiens Fc fragment of IgG, low affinity IIa, receptor for (CD32) (FCGR2A), mRNA. /FEA=mRNA /GEN=FCGR2A /PROD=Fc fragment of IgG, low affinity IIa, receptorfor (CD32) /DB_XREF=gi:11056051 /UG=Hs.78864 Fc fragment of IgG, low affinity IIa, receptor for (CD32) /FL=gb:NM_021642.1 gb:M31932.1 gb:J03619.1 gb:M28697.1 NM_021642 Fc fragment of IgG, low affinity IIa, receptor (CD32) FCGR2A 2212 NM_001136219 /// NM_021642 /// XM_005244960 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 203562_at NM_005103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005103.2 /DEF=Homo sapiens fasciculation and elongation protein zeta 1 (zygin I) (FEZ1), transcript variant 1, mRNA. /FEA=mRNA /GEN=FEZ1 /PROD=zygin 1, isoform 1 /DB_XREF=gi:12025681 /UG=Hs.79226 fasciculation and elongation protein zeta 1 (zygin I) /FL=gb:NM_005103.2 gb:U69139.1 gb:U60060.1 NM_005103 fasciculation and elongation protein zeta 1 (zygin I) FEZ1 9638 NM_005103 /// NM_022549 /// XM_005271734 /// XM_005271735 0006810 // transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051654 // establishment of mitochondrion localization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203563_at NM_021638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021638.1 /DEF=Homo sapiens actin filament associated protein (AFAP), mRNA. /FEA=mRNA /GEN=AFAP /PROD=actin filament associated protein /DB_XREF=gi:11056013 /UG=Hs.80306 actin filament associated protein /FL=gb:AF188700.1 gb:NM_021638.1 NM_021638 actin filament associated protein 1 AFAP1 60312 NM_001134647 /// NM_021638 /// NM_198595 /// XM_006713908 /// XM_006713909 /// XM_006713910 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203564_at NM_004629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004629.1 /DEF=Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA. /FEA=mRNA /GEN=FANCG /PROD=X-ray repair complementing defective repair inChinese hamster cells 9 /DB_XREF=gi:4759335 /UG=Hs.8047 Fanconi anemia, complementation group G /FL=gb:BC000032.1 gb:U70310.1 gb:NM_004629.1 NM_004629 Fanconi anemia, complementation group G FANCG 2189 NM_004629 0000075 // cell cycle checkpoint // traceable author statement /// 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007286 // spermatid development // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0003684 // damaged DNA binding // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203565_s_at NM_002431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002431.1 /DEF=Homo sapiens menage a trois 1 (CAK assembly factor) (MNAT1), mRNA. /FEA=mRNA /GEN=MNAT1 /PROD=menage a trois 1 (CAK assembly factor) /DB_XREF=gi:4505224 /UG=Hs.82380 menage a trois 1 (CAK assembly factor) /FL=gb:BC000820.1 gb:NM_002431.1 NM_002431 MNAT CDK-activating kinase assembly factor 1 MNAT1 4331 NM_001177963 /// NM_002431 /// XM_005267687 /// XM_005267688 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0021591 // ventricular system development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044236 // multicellular organismal metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 203566_s_at NM_000645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000645.1 /DEF=Homo sapiens amylo-1,6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) (AGL), transcript variant 5, mRNA. /FEA=mRNA /GEN=AGL /PROD=amylo-1,6-glucosidase,4-alpha-glucanotransferase isoform 2 /DB_XREF=gi:4557282 /UG=Hs.904 amylo-1,6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) /FL=gb:M85168.1 gb:NM_000645.1 NM_000645 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase AGL 178 NM_000028 /// NM_000642 /// NM_000643 /// NM_000644 /// NM_000645 /// NM_000646 /// XM_005270557 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // not recorded /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016234 // inclusion body // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0043033 // isoamylase complex // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004133 // glycogen debranching enzyme activity // traceable author statement /// 0004134 // 4-alpha-glucanotransferase activity // not recorded /// 0004135 // amylo-alpha-1,6-glucosidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from electronic annotation 203567_s_at AU157590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157590 /FEA=EST /DB_XREF=gi:11019111 /DB_XREF=est:AU157590 /CLONE=PLACE1008438 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1 AU157590 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203568_s_at NM_006355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006355.1 /DEF=Homo sapiens ring finger protein 15 (RNF15), mRNA. /FEA=mRNA /GEN=RNF15 /PROD=ring finger protein 15 /DB_XREF=gi:5454013 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1 NM_006355 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203569_s_at NM_003611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003611.1 /DEF=Homo sapiens chromosome X open reading frame 5 (CXORF5), mRNA. /FEA=mRNA /GEN=CXORF5 /PROD=chromosome X open reading frame 5 /DB_XREF=gi:4503178 /UG=Hs.6483 oral-facial-digital syndrome 1 gene /FL=gb:NM_003611.1 NM_003611 oral-facial-digital syndrome 1 OFD1 8481 NM_003611 /// XM_005274599 /// XM_005274600 /// XM_005274601 /// XM_005274602 /// XM_005274603 /// XM_005274604 /// XM_005274605 /// XM_005274606 /// XM_005274607 /// XM_005274609 /// XR_247288 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from sequence or structural similarity /// 0090307 // spindle assembly involved in mitosis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from sequence or structural similarity /// 0043015 // gamma-tubulin binding // inferred from sequence or structural similarity 203570_at NM_005576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005576.1 /DEF=Homo sapiens lysyl oxidase-like 1 (LOXL1), mRNA. /FEA=mRNA /GEN=LOXL1 /PROD=lysyl oxidase-like 1 /DB_XREF=gi:5031882 /UG=Hs.65436 lysyl oxidase-like 1 /FL=gb:L21186.1 gb:NM_005576.1 NM_005576 lysyl oxidase-like 1 LOXL1 4016 NM_005576 0018277 // protein deamination // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203571_s_at NM_006829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006829.1 /DEF=Homo sapiens adipose specific 2 (APM2), mRNA. /FEA=mRNA /GEN=APM2 /PROD=adipose specific 2 /DB_XREF=gi:5802975 /UG=Hs.74120 adipose specific 2 /FL=gb:BC004471.1 gb:NM_006829.1 gb:D45370.1 NM_006829 adipogenesis regulatory factor ADIRF 10974 NM_006829 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071478 // cellular response to radiation // inferred from direct assay /// 0072719 // cellular response to cisplatin // inferred from direct assay /// 2001023 // regulation of response to drug // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 203572_s_at NM_005641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005641.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, E, 7085kD (TAF2E), mRNA. /FEA=mRNA /GEN=TAF2E /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, E, 7085kD /DB_XREF=gi:5032146 /UG=Hs.78865 TATA box binding protein (TBP)-associated factor, RNA polymerase II, E, 7085kD /FL=gb:NM_005641.1 gb:L25444.1 NM_005641 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa TAF6 6878 NM_001190415 /// NM_005641 /// NM_139122 /// NM_139123 /// NM_139315 /// NR_033792 /// XM_006716100 /// XM_006716101 /// XM_006716102 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203573_s_at NM_004581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004581.1 /DEF=Homo sapiens Rab geranylgeranyltransferase, alpha subunit (RABGGTA), mRNA. /FEA=mRNA /GEN=RABGGTA /PROD=Rab geranylgeranyltransferase, alpha subunit /DB_XREF=gi:4759015 /UG=Hs.78920 Rab geranylgeranyltransferase, alpha subunit /FL=gb:NM_004581.1 NM_004581 Rab geranylgeranyltransferase, alpha subunit RABGGTA 5875 NM_004581 /// NM_182836 /// XM_005267959 /// XM_005267960 0006464 // cellular protein modification process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203574_at NM_005384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005384.1 /DEF=Homo sapiens nuclear factor, interleukin 3 regulated (NFIL3), mRNA. /FEA=mRNA /GEN=NFIL3 /PROD=nuclear factor, interleukin 3 regulated /DB_XREF=gi:4885516 /UG=Hs.79334 nuclear factor, interleukin 3 regulated /FL=gb:U26173.1 gb:NM_005384.1 NM_005384 nuclear factor, interleukin 3 regulated NFIL3 4783 NM_001289999 /// NM_001290000 /// NM_005384 /// XM_005251999 /// XM_005252000 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203575_at NM_001896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001896.1 /DEF=Homo sapiens casein kinase 2, alpha prime polypeptide (CSNK2A2), mRNA. /FEA=mRNA /GEN=CSNK2A2 /PROD=casein kinase 2, alpha prime polypeptide /DB_XREF=gi:4503096 /UG=Hs.82201 casein kinase 2, alpha prime polypeptide /FL=gb:M55268.1 gb:NM_001896.1 NM_001896 casein kinase 2, alpha prime polypeptide CSNK2A2 1459 NM_001896 /// XM_005255799 /// XM_005255800 /// XM_005255801 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 203576_at NM_001190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001190.1 /DEF=Homo sapiens branched chain aminotransferase 2, mitochondrial (BCAT2), mRNA. /FEA=mRNA /GEN=BCAT2 /PROD=branched chain aminotransferase 2,mitochondrial /DB_XREF=gi:4502374 /UG=Hs.101408 branched chain aminotransferase 2, mitochondrial /FL=gb:BC001900.1 gb:BC004243.1 gb:U62739.1 gb:U68418.1 gb:NM_001190.1 NM_001190 branched chain amino-acid transaminase 2, mitochondrial BCAT2 587 NM_001164773 /// NM_001190 /// NM_001284325 /// NR_028451 0006549 // isoleucine metabolic process // inferred from electronic annotation /// 0006550 // isoleucine catabolic process // inferred from electronic annotation /// 0006551 // leucine metabolic process // inferred from electronic annotation /// 0006573 // valine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0010817 // regulation of hormone levels // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation 203577_at NM_001517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001517.1 /DEF=Homo sapiens general transcription factor IIH, polypeptide 4 (52kD subunit) (GTF2H4), mRNA. /FEA=mRNA /GEN=GTF2H4 /PROD=general transcription factor IIH, polypeptide 4(52kD subunit) /DB_XREF=gi:4504200 /UG=Hs.102910 general transcription factor IIH, polypeptide 4 (52kD subunit) /FL=gb:BC004935.1 gb:NM_001517.1 NM_001517 general transcription factor IIH, polypeptide 4, 52kDa GTF2H4 2968 NM_001517 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation 203578_s_at BG230586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230586 /FEA=EST /DB_XREF=gi:12725619 /DB_XREF=est:naf40g01.x1 /CLONE=IMAGE:4143552 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1 BG230586 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203579_s_at AI660619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI660619 /FEA=EST /DB_XREF=gi:4764202 /DB_XREF=est:wf21h04.x1 /CLONE=IMAGE:2351287 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1 AI660619 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203580_s_at NM_003983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003983.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), mRNA. /FEA=mRNA /GEN=SLC7A6 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 6 /DB_XREF=gi:4507052 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1 NM_003983 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203581_at BC002438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002438.1 /DEF=Homo sapiens, RAB4, member RAS oncogene family, clone MGC:1486, mRNA, complete cds. /FEA=mRNA /PROD=RAB4, member RAS oncogene family /DB_XREF=gi:12803248 /UG=Hs.119007 RAB4, member RAS oncogene family /FL=gb:BC002438.1 gb:BC004309.1 gb:NM_004578.1 gb:M28211.1 BC002438 RAB4A, member RAS oncogene family /// S-phase response (cyclin related) RAB4A /// SPHAR 5867 /// 10638 NM_001271998 /// NM_004578 /// NM_006542 /// NR_073545 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 203582_s_at NM_004578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004578.1 /DEF=Homo sapiens RAB4, member RAS oncogene family (RAB4), mRNA. /FEA=mRNA /GEN=RAB4 /PROD=RAB4, member RAS oncogene family /DB_XREF=gi:4759001 /UG=Hs.119007 RAB4, member RAS oncogene family /FL=gb:BC002438.1 gb:BC004309.1 gb:NM_004578.1 gb:M28211.1 NM_004578 RAB4A, member RAS oncogene family /// S-phase response (cyclin related) RAB4A /// SPHAR 5867 /// 10638 NM_001271998 /// NM_004578 /// NM_006542 /// NR_073545 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 203583_at NM_014044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014044.1 /DEF=Homo sapiens DKFZP564G0222 protein (DKFZP564G0222), mRNA. /FEA=mRNA /GEN=DKFZP564G0222 /PROD=DKFZP564G0222 protein /DB_XREF=gi:7661609 /UG=Hs.13370 DKFZP564G0222 protein /FL=gb:AF077038.1 gb:AL080115.1 gb:NM_014044.1 NM_014044 unc-50 homolog (C. elegans) UNC50 25972 NM_014044 /// XM_005263913 /// XM_006712403 /// XM_006712404 0006810 // transport // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 203584_at NM_014673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014673.1 /DEF=Homo sapiens KIAA0103 gene product (KIAA0103), mRNA. /FEA=mRNA /GEN=KIAA0103 /PROD=KIAA0103 gene product /DB_XREF=gi:7661909 /UG=Hs.154387 KIAA0103 gene product /FL=gb:D14659.1 gb:NM_014673.1 NM_014673 ER membrane protein complex subunit 2 EMC2 9694 NM_014673 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203585_at NM_007150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007150.1 /DEF=Homo sapiens zinc finger protein 185 (LIM domain) (ZNF185), mRNA. /FEA=mRNA /GEN=ZNF185 /PROD=zinc finger protein 185 (LIM domain) /DB_XREF=gi:6005971 /UG=Hs.16622 zinc finger protein 185 (LIM domain) /FL=gb:NM_007150.1 NM_007150 zinc finger protein 185 (LIM domain) ZNF185 7739 NM_001178106 /// NM_001178107 /// NM_001178108 /// NM_001178109 /// NM_001178110 /// NM_001178113 /// NM_001178114 /// NM_001178115 /// NM_007150 /// XM_005274730 /// XM_005274731 /// XM_005274732 /// XM_005274733 /// XM_005274734 /// XM_005274735 /// XM_005274736 /// XM_005274737 /// XM_005274738 /// XM_005274739 /// XM_005274740 /// XM_005274741 /// XM_005274742 /// XM_005274744 /// XM_005274745 /// XM_005274746 /// XM_006724843 /// XM_006724844 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203586_s_at NM_001661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001661.1 /DEF=Homo sapiens ADP-ribosylation factor 4-like (ARF4L), mRNA. /FEA=mRNA /GEN=ARF4L /PROD=ADP-ribosylation factor 4-like /DB_XREF=gi:4502206 /UG=Hs.183153 ADP-ribosylation factor 4-like /FL=gb:BC000043.1 gb:NM_001661.1 gb:L38490.1 gb:U25771.1 NM_001661 ADP-ribosylation factor-like 4D ARL4D 379 NM_001661 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203587_at U25771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U25771.1 /DEF=Human ADP-ribosylation factor mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor /DB_XREF=gi:808069 /UG=Hs.183153 ADP-ribosylation factor 4-like /FL=gb:BC000043.1 gb:NM_001661.1 gb:L38490.1 gb:U25771.1 U25771 ADP-ribosylation factor-like 4D ARL4D 379 NM_001661 0006184 // GTP catabolic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203588_s_at BG034328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG034328 /FEA=EST /DB_XREF=gi:12427528 /DB_XREF=est:602302213F1 /CLONE=IMAGE:4403787 /UG=Hs.19131 transcription factor Dp-2 (E2F dimerization partner 2) /FL=gb:NM_006286.1 gb:U18422.1 BG034328 transcription factor Dp-2 (E2F dimerization partner 2) TFDP2 7029 NM_001178138 /// NM_001178139 /// NM_001178140 /// NM_001178141 /// NM_001178142 /// NM_006286 /// XM_005247731 /// XM_005247733 /// XM_005247734 /// XM_005247735 /// XM_006713737 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 203589_s_at NM_006286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006286.1 /DEF=Homo sapiens transcription factor Dp-2 (E2F dimerization partner 2) (TFDP2), mRNA. /FEA=mRNA /GEN=TFDP2 /PROD=transcription factor Dp-2 (E2F dimerizationpartner 2) /DB_XREF=gi:5454111 /UG=Hs.19131 transcription factor Dp-2 (E2F dimerization partner 2) /FL=gb:NM_006286.1 gb:U18422.1 NM_006286 transcription factor Dp-2 (E2F dimerization partner 2) TFDP2 7029 NM_001178138 /// NM_001178139 /// NM_001178140 /// NM_001178141 /// NM_001178142 /// NM_006286 /// XM_005247731 /// XM_005247733 /// XM_005247734 /// XM_005247735 /// XM_006713737 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 203590_at NM_006141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006141.1 /DEF=Homo sapiens dynein, cytoplasmic, light intermediate polypeptide 2 (DNCLI2), mRNA. /FEA=mRNA /GEN=DNCLI2 /PROD=dynein, cytoplasmic, light intermediatepolypeptide 2 /DB_XREF=gi:5453633 /UG=Hs.194625 dynein, cytoplasmic, light intermediate polypeptide 2 /FL=gb:AF035812.1 gb:NM_006141.1 NM_006141 dynein, cytoplasmic 1, light intermediate chain 2 DYNC1LI2 1783 NM_001286157 /// NM_006141 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051642 // centrosome localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 203591_s_at NM_000760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000760.1 /DEF=Homo sapiens colony stimulating factor 3 receptor (granulocyte) (CSF3R), mRNA. /FEA=mRNA /GEN=CSF3R /PROD=colony stimulating factor 3 receptor(granulocyte) /DB_XREF=gi:4503080 /UG=Hs.2175 colony stimulating factor 3 receptor (granulocyte) /FL=gb:M59818.1 gb:NM_000760.1 NM_000760 colony stimulating factor 3 receptor (granulocyte) CSF3R 1441 NM_000760 /// NM_156038 /// NM_156039 /// NM_172313 /// XM_005270492 /// XM_005270493 /// XM_005270495 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203592_s_at NM_005860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005860.1 /DEF=Homo sapiens follistatin-like 3 (secreted glycoprotein) (FSTL3), mRNA. /FEA=mRNA /GEN=FSTL3 /PROD=follistatin-like 3 glycoprotein /DB_XREF=gi:5031700 /UG=Hs.25348 follistatin-like 3 (secreted glycoprotein) /FL=gb:U76702.1 gb:NM_005860.1 NM_005860 follistatin-like 3 (secreted glycoprotein) FSTL3 10272 NM_005860 0001503 // ossification // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0090101 // negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation 0001968 // fibronectin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 203593_at NM_012120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012120.1 /DEF=Homo sapiens CD2-associated protein (CD2AP), mRNA. /FEA=mRNA /GEN=CD2AP /PROD=CD2-associated protein /DB_XREF=gi:11321633 /UG=Hs.265561 CD2-associated protein /FL=gb:NM_012120.1 gb:AF146277.1 gb:AF164377.1 NM_012120 CD2-associated protein CD2AP 23607 NM_012120 /// XM_005248976 /// XM_005248977 0006461 // protein complex assembly // traceable author statement /// 0006930 // substrate-dependent cell migration, cell extension // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0016050 // vesicle organization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0048259 // regulation of receptor-mediated endocytosis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005172 // vascular endothelial growth factor receptor binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 203594_at NM_003729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003729.1 /DEF=Homo sapiens RNA 3-terminal phosphate cyclase (RPC), mRNA. /FEA=mRNA /GEN=RPC /PROD=RNA 3-terminal phosphate cyclase /DB_XREF=gi:4506588 /UG=Hs.27076 RNA 3-terminal phosphate cyclase /FL=gb:NM_003729.1 NM_003729 RNA 3'-terminal phosphate cyclase RTCA 8634 NM_001130841 /// NM_003729 /// XM_005271298 /// XM_005271299 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003963 // RNA-3'-phosphate cyclase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203595_s_at N47725 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N47725 /FEA=EST /DB_XREF=gi:1188891 /DB_XREF=est:yy92h11.s1 /CLONE=IMAGE:281061 /UG=Hs.27610 retinoic acid- and interferon-inducible protein (58kD) /FL=gb:U34605.1 gb:NM_012420.1 N47725 interferon-induced protein with tetratricopeptide repeats 5 IFIT5 24138 NM_012420 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203596_s_at NM_012420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012420.1 /DEF=Homo sapiens retinoic acid- and interferon-inducible protein (58kD) (RI58), mRNA. /FEA=mRNA /GEN=RI58 /PROD=retinoic acid- and interferon-inducible protein(58kD) /DB_XREF=gi:6912629 /UG=Hs.27610 retinoic acid- and interferon-inducible protein (58kD) /FL=gb:U34605.1 gb:NM_012420.1 NM_012420 interferon-induced protein with tetratricopeptide repeats 5 IFIT5 24138 NM_012420 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203597_s_at AI734228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI734228 /FEA=EST /DB_XREF=gi:5055341 /DB_XREF=est:zb57d10.y5 /CLONE=IMAGE:307699 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2 AI734228 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203598_s_at AK000979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000979.1 /DEF=Homo sapiens cDNA FLJ10117 fis, clone HEMBA1002810, highly similar to Homo sapiens formin binding protein 21 mRNA. /FEA=mRNA /DB_XREF=gi:7021977 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2 AK000979 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203599_s_at NM_007187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007187.2 /DEF=Homo sapiens WW domain binding protein 4 (formin binding protein 21) (WBP4), mRNA. /FEA=mRNA /GEN=WBP4 /PROD=WW domain-containing binding protein 4 /DB_XREF=gi:9943844 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2 NM_007187 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203600_s_at NM_003704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003704.1 /DEF=Homo sapiens gene with multiple splice variants near HD locus on 4p16.3 (RES4-22), mRNA. /FEA=mRNA /GEN=RES4-22 /PROD=gene with multiple splice variants near HD locuson 4p16.3 /DB_XREF=gi:4506480 /UG=Hs.325987 gene with multiple splice variants near HD locus on 4p16.3 /FL=gb:AB000459.1 gb:NM_003704.1 NM_003704 family with sequence similarity 193, member A FAM193A 8603 NM_001256666 /// NM_001256667 /// NM_001256668 /// NM_003704 /// NR_046335 /// NR_046336 /// XM_006713930 /// XM_006713931 /// XM_006713932 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203601_s_at AW574837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW574837 /FEA=EST /DB_XREF=gi:7246376 /DB_XREF=est:UI-HF-BK0-abj-e-01-0-UI.s1 /CLONE=IMAGE:3056353 /UG=Hs.33532 zinc finger protein 151 (pHZ-67) /FL=gb:NM_003443.1 AW574837 zinc finger and BTB domain containing 17 ZBTB17 7709 NM_001242884 /// NM_001287603 /// NM_001287604 /// NM_003443 /// XM_005245986 /// XM_005245987 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203602_s_at NM_003443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003443.1 /DEF=Homo sapiens zinc finger protein 151 (pHZ-67) (ZNF151), mRNA. /FEA=mRNA /GEN=ZNF151 /PROD=zinc finger protein 151 (pHZ-67) /DB_XREF=gi:4507996 /UG=Hs.33532 zinc finger protein 151 (pHZ-67) /FL=gb:NM_003443.1 NM_003443 zinc finger and BTB domain containing 17 ZBTB17 7709 NM_001242884 /// NM_001287603 /// NM_001287604 /// NM_003443 /// XM_005245986 /// XM_005245987 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203603_s_at NM_014795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014795.1 /DEF=Homo sapiens zinc finger homeobox 1B (ZFHX1B), mRNA. /FEA=mRNA /GEN=ZFHX1B /PROD=zinc finger homeobox 1B /DB_XREF=gi:7662183 /UG=Hs.34871 zinc finger homeobox 1B /FL=gb:AB011141.1 gb:NM_014795.1 NM_014795 zinc finger E-box binding homeobox 2 ZEB2 9839 NM_001171653 /// NM_014795 /// NR_033258 /// XM_006712881 /// XM_006712882 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045636 // positive regulation of melanocyte differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048023 // positive regulation of melanin biosynthetic process // inferred by curator /// 0048066 // developmental pigmentation // inferred from sequence or structural similarity /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0097324 // melanocyte migration // inferred from sequence or structural similarity /// 1903056 // regulation of melanosome organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046332 // SMAD binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from electronic annotation 203604_at N38750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N38750 /FEA=EST /DB_XREF=gi:1161957 /DB_XREF=est:yy42c06.s1 /CLONE=IMAGE:273898 /UG=Hs.48450 KIAA0222 gene product /FL=gb:D86975.1 gb:NM_014643.1 N38750 zinc finger protein 516 ZNF516 9658 NM_014643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203605_at NM_003136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003136.1 /DEF=Homo sapiens signal recognition particle 54kD (SRP54), mRNA. /FEA=mRNA /GEN=SRP54 /PROD=signal recognition particle 54kD /DB_XREF=gi:4507214 /UG=Hs.49346 signal recognition particle 54kD /FL=gb:U51920.1 gb:BC000652.1 gb:BC003389.1 gb:NM_003136.1 NM_003136 signal recognition particle 54kDa SRP54 6729 NM_001146282 /// NM_003136 /// XM_005268024 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred by curator /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006616 // SRP-dependent cotranslational protein targeting to membrane, translocation // inferred from sequence or structural similarity /// 0006617 // SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008312 // 7S RNA binding // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0030942 // endoplasmic reticulum signal peptide binding // inferred from direct assay /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203606_at NM_004553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004553.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Q reductase) (NDUFS6), mRNA. /FEA=mRNA /GEN=NDUFS6 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 6(13kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758791 /UG=Hs.49767 NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Q reductase) /FL=gb:AF044959.1 gb:NM_004553.1 NM_004553 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) NDUFS6 4726 NM_004553 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061458 // reproductive system development // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement 203607_at NM_014937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014937.1 /DEF=Homo sapiens KIAA0966 protein (KIAA0966), mRNA. /FEA=mRNA /GEN=KIAA0966 /PROD=KIAA0966 protein /DB_XREF=gi:7662413 /UG=Hs.52463 KIAA0966 protein /FL=gb:AF113227.1 gb:AB023183.1 gb:NM_014937.1 NM_014937 inositol polyphosphate-5-phosphatase F INPP5F 22876 NM_001243194 /// NM_001243195 /// NM_014937 /// XM_006717719 /// XM_006717720 0008152 // metabolic process // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0031161 // phosphatidylinositol catabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 203608_at AL031230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031230 /DEF=Human DNA sequence from clone 73M23 on chromosome 6p22.2-22.3. Contains the 5 part of the possibly alternatively spliced gene for Phosphatidylinositol-glycan-specific Phospholipase D 1 precursor (EC 3.1.4.50, PIGPLD1, Glycoprotein Phospholipase D... /FEA=mRNA_5 /DB_XREF=gi:3947845 /UG=Hs.5299 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) /FL=gb:NM_001080.1 AL031230 aldehyde dehydrogenase 5 family, member A1 ALDH5A1 7915 NM_001080 /// NM_170740 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006083 // acetate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006650 // glycerophospholipid metabolic process // inferred from sequence or structural similarity /// 0006678 // glucosylceramide metabolic process // inferred from electronic annotation /// 0006681 // galactosylceramide metabolic process // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from direct assay /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from mutant phenotype /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0042135 // neurotransmitter catabolic process // inferred from sequence or structural similarity /// 0046459 // short-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from direct assay /// 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0009013 // succinate-semialdehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred by curator 203609_s_at NM_001080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001080.1 /DEF=Homo sapiens aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) (ALDH5A1), mRNA. /FEA=mRNA /GEN=ALDH5A1 /PROD=aldehyde dehydrogenase 5 family, member A1(succinate-semialdehyde dehydrogenase) /DB_XREF=gi:4507228 /UG=Hs.5299 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) /FL=gb:NM_001080.1 NM_001080 aldehyde dehydrogenase 5 family, member A1 ALDH5A1 7915 NM_001080 /// NM_170740 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006083 // acetate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006650 // glycerophospholipid metabolic process // inferred from sequence or structural similarity /// 0006678 // glucosylceramide metabolic process // inferred from electronic annotation /// 0006681 // galactosylceramide metabolic process // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from direct assay /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from mutant phenotype /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0042135 // neurotransmitter catabolic process // inferred from sequence or structural similarity /// 0046459 // short-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from direct assay /// 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0009013 // succinate-semialdehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred by curator 203610_s_at AI363270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI363270 /FEA=EST /DB_XREF=gi:4114891 /DB_XREF=est:qy56f11.x1 /CLONE=IMAGE:2016045 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1 AI363270 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203611_at NM_005652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005652.1 /DEF=Homo sapiens telomeric repeat binding factor 2 (TERF2), mRNA. /FEA=mRNA /GEN=TERF2 /PROD=telomeric repeat binding factor 2 /DB_XREF=gi:5032168 /UG=Hs.100030 telomeric repeat binding factor 2 /FL=gb:AF002999.1 gb:NM_005652.1 NM_005652 telomeric repeat binding factor 2 TERF2 7014 NM_005652 /// XM_005256121 /// XM_005256122 /// XM_005256123 /// XM_005256124 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // non-traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // inferred by curator /// 0007049 // cell cycle // inferred from electronic annotation /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0016233 // telomere capping // inferred from mutant phenotype /// 0031627 // telomeric loop formation // inferred from direct assay /// 0031848 // protection from non-homologous end joining at telomere // inferred from mutant phenotype /// 0032205 // negative regulation of telomere maintenance // inferred from direct assay /// 0032206 // positive regulation of telomere maintenance // inferred from electronic annotation /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0090398 // cellular senescence // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 203612_at NM_004053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004053.1 /DEF=Homo sapiens bystin-like (BYSL), mRNA. /FEA=mRNA /GEN=BYSL /PROD=bystin /DB_XREF=gi:4757881 /UG=Hs.106880 bystin-like /FL=gb:L36720.1 gb:NM_004053.1 NM_004053 bystin-like BYSL 705 NM_004053 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203613_s_at NM_002493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002493.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD, B17) (NDUFB6), mRNA. /FEA=mRNA /GEN=NDUFB6 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 6 (17kD, B17) /DB_XREF=gi:4505364 /UG=Hs.109646 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD, B17) /FL=gb:AF035840.1 gb:NM_002493.1 gb:AF067167.1 NM_002493 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa NDUFB6 4712 NM_001199987 /// NM_002493 /// NM_182739 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203614_at NM_021645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021645.1 /DEF=Homo sapiens KIAA0266 gene product (KIAA0266), mRNA. /FEA=mRNA /GEN=KIAA0266 /PROD=KIAA0266 gene product /DB_XREF=gi:11063982 /UG=Hs.127376 KIAA0266 gene product /FL=gb:NM_021645.1 gb:D87455.1 NM_021645 ALG11, alpha-1,2-mannosyltransferase /// UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) ALG11 /// UTP14C 9724 /// 440138 NM_001004127 /// NM_021645 /// NR_036571 0006364 // rRNA processing // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0004377 // GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 203615_x_at NM_001055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001055.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (SULT1A1), mRNA. /FEA=mRNA /GEN=SULT1A1 /PROD=sulfotransferase family, cytosolic, 1A,phenol-preferring, member 1 /DB_XREF=gi:4507300 /UG=Hs.142 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 /FL=gb:BC000923.2 gb:L10819.1 gb:L19955.1 gb:L19999.1 gb:NM_001055.1 gb:U09031.1 gb:U26309.1 NM_001055 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 SULT1A1 6817 NM_001055 /// NM_177529 /// NM_177530 /// NM_177534 /// NM_177536 /// XM_005255522 /// XM_006721078 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0009308 // amine metabolic process // traceable author statement /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004062 // aryl sulfotransferase activity // inferred from direct assay /// 0004062 // aryl sulfotransferase activity // traceable author statement /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay /// 0050294 // steroid sulfotransferase activity // inferred from direct assay 203616_at NM_002690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002690.1 /DEF=Homo sapiens polymerase (DNA directed), beta (POLB), mRNA. /FEA=mRNA /GEN=POLB /PROD=polymerase (DNA directed), beta /DB_XREF=gi:4505930 /UG=Hs.180107 polymerase (DNA directed), beta /FL=gb:M13140.1 gb:L11607.1 gb:NM_002690.1 gb:D29013.1 NM_002690 polymerase (DNA directed), beta POLB 5423 NM_002690 /// XM_005273535 /// XM_005273536 /// XM_005273537 /// XM_005273538 /// XM_005273539 /// XM_005273540 /// XM_006716353 /// XR_428311 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006284 // base-excision repair // traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from electronic annotation /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071897 // DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005876 // spindle microtubule // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203617_x_at NM_005229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005229.2 /DEF=Homo sapiens ELK1, member of ETS oncogene family (ELK1), mRNA. /FEA=mRNA /GEN=ELK1 /PROD=ELK1 protein /DB_XREF=gi:11496880 /UG=Hs.181128 ELK1, member of ETS oncogene family /FL=gb:NM_005229.2 gb:AB016193.1 NM_005229 ELK1, member of ETS oncogene family ELK1 2002 NM_001114123 /// NM_001257168 /// NM_005229 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203618_at AB023167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023167.1 /DEF=Homo sapiens mRNA for KIAA0950 protein, partial cds. /FEA=mRNA /GEN=KIAA0950 /PROD=KIAA0950 protein /DB_XREF=gi:4589543 /UG=Hs.182859 lifeguard /FL=gb:BC000051.1 gb:AF190461.1 gb:NM_012306.1 AB023167 Fas apoptotic inhibitory molecule 2 FAIM2 23017 NM_012306 /// XM_005268730 0006915 // apoptotic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0021680 // cerebellar Purkinje cell layer development // inferred from sequence or structural similarity /// 0021681 // cerebellar granular layer development // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 203619_s_at NM_012306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012306.1 /DEF=Homo sapiens lifeguard (KIAA0950), mRNA. /FEA=mRNA /GEN=KIAA0950 /PROD=lifeguard /DB_XREF=gi:6912467 /UG=Hs.182859 lifeguard /FL=gb:BC000051.1 gb:AF190461.1 gb:NM_012306.1 NM_012306 Fas apoptotic inhibitory molecule 2 FAIM2 23017 NM_012306 /// XM_005268730 0006915 // apoptotic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0021680 // cerebellar Purkinje cell layer development // inferred from sequence or structural similarity /// 0021681 // cerebellar granular layer development // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 203620_s_at NM_014824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014824.1 /DEF=Homo sapiens KIAA0769 gene product (KIAA0769), mRNA. /FEA=mRNA /GEN=KIAA0769 /PROD=KIAA0769 gene product /DB_XREF=gi:7662295 /UG=Hs.19056 KIAA0769 gene product /FL=gb:AB018312.1 gb:NM_014824.1 NM_014824 FCH and double SH3 domains 2 FCHSD2 9873 NM_014824 0005515 // protein binding // inferred from physical interaction 203621_at NM_002492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002492.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD, SGDH) (NDUFB5), mRNA. /FEA=mRNA /GEN=NDUFB5 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 5 (16kD, SGDH) /DB_XREF=gi:4505362 /UG=Hs.19236 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD, SGDH) /FL=gb:BC005271.1 gb:AF047181.1 gb:NM_002492.1 NM_002492 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa NDUFB5 4711 NM_001199957 /// NM_001199958 /// NM_002492 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203622_s_at NM_020143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020143.1 /DEF=Homo sapiens putatative 28 kDa protein (LOC56902), mRNA. /FEA=mRNA /GEN=LOC56902 /PROD=putatative 28 kDa protein /DB_XREF=gi:10047139 /UG=Hs.193384 putatative 28 kDa protein /FL=gb:NM_020143.1 gb:AF164799.1 NM_020143 partner of NOB1 homolog (S. cerevisiae) PNO1 56902 NM_020143 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203623_at AI675453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI675453 /FEA=EST /DB_XREF=gi:4875933 /DB_XREF=est:wb99f04.x1 /CLONE=IMAGE:2313823 /UG=Hs.21432 SEX gene /FL=gb:NM_017514.1 AI675453 plexin A3 PLXNA3 55558 NM_017514 /// XM_005274705 /// XM_005274706 /// XM_006724829 /// XM_006724830 /// XR_430556 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051495 // positive regulation of cytoskeleton organization // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // non-traceable author statement 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from electronic annotation 203624_at NM_005088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005088.1 /DEF=Homo sapiens DNA segment on chromosome X and Y (unique) 155 expressed sequence (DXYS155E), mRNA. /FEA=mRNA /GEN=DXYS155E /PROD=DNA segment on chromosome X and Y (unique) 155expressed sequence /DB_XREF=gi:10835221 /UG=Hs.21595 DNA segment on chromosome X and Y (unique) 155 expressed sequence /FL=gb:NM_005088.1 NM_005088 A kinase (PRKA) anchor protein 17A AKAP17A 8227 NM_005088 /// NR_027383 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042113 // B cell activation // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 2000019 // negative regulation of male gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from direct assay /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 203625_x_at BG105365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG105365 /FEA=EST /DB_XREF=gi:12599141 /DB_XREF=est:602312473F1 /CLONE=IMAGE:4422043 /UG=Hs.23348 S-phase kinase-associated protein 2 (p45) /FL=gb:NM_005983.1 gb:U33761.1 BG105365 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase SKP2 6502 NM_001243120 /// NM_005983 /// NM_032637 /// XM_006714487 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016235 // aggresome // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203626_s_at NM_005983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005983.1 /DEF=Homo sapiens S-phase kinase-associated protein 2 (p45) (SKP2), mRNA. /FEA=mRNA /GEN=SKP2 /PROD=S-phase kinase-associated protein 2 (p45) /DB_XREF=gi:5174684 /UG=Hs.23348 S-phase kinase-associated protein 2 (p45) /FL=gb:NM_005983.1 gb:U33761.1 NM_005983 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase SKP2 6502 NM_001243120 /// NM_005983 /// NM_032637 /// XM_006714487 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016235 // aggresome // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203627_at AI830698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI830698 /FEA=EST /DB_XREF=gi:5451454 /DB_XREF=est:wj52f06.x1 /CLONE=IMAGE:2406467 /UG=Hs.239176 insulin-like growth factor 1 receptor /FL=gb:NM_000875.2 AI830698 insulin-like growth factor 1 receptor IGF1R 3480 NM_000875 /// NM_001291858 /// NM_152452 /// XM_005254896 /// XM_005254897 /// XM_006720486 /// XM_006720487 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051389 // inactivation of MAPKK activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction 203628_at H05812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H05812 /FEA=EST /DB_XREF=gi:869364 /DB_XREF=est:yl77f04.s1 /CLONE=IMAGE:44149 /UG=Hs.239176 insulin-like growth factor 1 receptor /FL=gb:NM_000875.2 H05812 insulin-like growth factor 1 receptor IGF1R 3480 NM_000875 /// NM_001291858 /// NM_152452 /// XM_005254896 /// XM_005254897 /// XM_006720486 /// XM_006720487 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051389 // inactivation of MAPKK activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction 203629_s_at AU152134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152134 /FEA=EST /DB_XREF=gi:11013655 /DB_XREF=est:AU152134 /CLONE=NT2RP3000274 /UG=Hs.239631 golgi transport complex 1 (90 kDa subunit) /FL=gb:AF058718.1 gb:NM_006348.1 AU152134 component of oligomeric golgi complex 5 COG5 10466 NM_001161520 /// NM_006348 /// NM_181733 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 203630_s_at NM_006348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006348.1 /DEF=Homo sapiens golgi transport complex 1 (90 kDa subunit) (GOLTC1), mRNA. /FEA=mRNA /GEN=GOLTC1 /PROD=golgi transport complex 1 (90 kDa subunit) /DB_XREF=gi:5453669 /UG=Hs.239631 golgi transport complex 1 (90 kDa subunit) /FL=gb:AF058718.1 gb:NM_006348.1 NM_006348 component of oligomeric golgi complex 5 COG5 10466 NM_001161520 /// NM_006348 /// NM_181733 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 203631_s_at AF202640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF202640.1 /DEF=Homo sapiens orphan G-protein coupled receptor (GPRC5B) mRNA, complete cds. /FEA=mRNA /GEN=GPRC5B /PROD=orphan G-protein coupled receptor /DB_XREF=gi:7682556 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B /FL=gb:AF181862.1 gb:AF202640.1 gb:NM_016235.1 AF202640 G protein-coupled receptor, class C, group 5, member B GPRC5B 51704 NM_016235 /// XM_005255357 /// XM_006721051 /// XM_006721052 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005118 // sevenless binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030295 // protein kinase activator activity // inferred from direct assay 203632_s_at NM_016235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016235.1 /DEF=Homo sapiens G protein-coupled receptor, family C, group 5, member B (GPRC5B), mRNA. /FEA=mRNA /GEN=GPRC5B /PROD=G protein-coupled receptor, family C, group 5,member B, precursor /DB_XREF=gi:7706450 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B /FL=gb:AF181862.1 gb:AF202640.1 gb:NM_016235.1 NM_016235 G protein-coupled receptor, class C, group 5, member B GPRC5B 51704 NM_016235 /// XM_005255357 /// XM_006721051 /// XM_006721052 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005118 // sevenless binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030295 // protein kinase activator activity // inferred from direct assay 203633_at BF001714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001714 /FEA=EST /DB_XREF=gi:10701989 /DB_XREF=est:7g92b09.x1 /CLONE=IMAGE:3313913 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:NM_001876.1 gb:L39211.1 BF001714 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203634_s_at NM_001876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001876.1 /DEF=Homo sapiens carnitine palmitoyltransferase I, liver (CPT1A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CPT1A /PROD=liver carnitine palmitoyltransferase I /DB_XREF=gi:4503020 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:NM_001876.1 gb:L39211.1 NM_001876 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203635_at NM_006052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006052.1 /DEF=Homo sapiens Down syndrome critical region gene 3 (DSCR3), mRNA. /FEA=mRNA /GEN=DSCR3 /PROD=Down syndrome critical region protein 3 /DB_XREF=gi:5174424 /UG=Hs.26146 Down syndrome critical region gene 3 /FL=gb:D87343.1 gb:NM_006052.1 NM_006052 Down syndrome critical region gene 3 DSCR3 10311 NM_006052 /// XM_005260909 /// XM_005260911 0007034 // vacuolar transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0030904 // retromer complex // inferred from electronic annotation 203636_at BE967532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE967532 /FEA=EST /DB_XREF=gi:10578237 /DB_XREF=est:601649050F1 /CLONE=IMAGE:3932868 /UG=Hs.27695 midline 1 (OpitzBBB syndrome) /FL=gb:AF269101.1 gb:AF230976.1 gb:AF035360.1 gb:NM_000381.1 BE967532 midline 1 MID1 4281 NM_000381 /// NM_001098624 /// NM_001193277 /// NM_001193278 /// NM_001193279 /// NM_001193280 /// NM_001193281 /// NM_033289 /// NM_033290 /// NM_033291 /// XM_005274536 /// XM_005274537 /// XM_005274538 /// XM_006724492 /// XM_006724493 /// XR_247298 /// XR_247299 /// XR_247300 /// XR_250630 /// XR_250631 /// XR_250632 /// XR_254127 /// XR_254128 /// XR_254129 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 203637_s_at NM_000381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000381.1 /DEF=Homo sapiens midline 1 (OpitzBBB syndrome) (MID1), mRNA. /FEA=mRNA /GEN=MID1 /PROD=midline 1 /DB_XREF=gi:4557752 /UG=Hs.27695 midline 1 (OpitzBBB syndrome) /FL=gb:AF269101.1 gb:AF230976.1 gb:AF035360.1 gb:NM_000381.1 NM_000381 midline 1 MID1 4281 NM_000381 /// NM_001098624 /// NM_001193277 /// NM_001193278 /// NM_001193279 /// NM_001193280 /// NM_001193281 /// NM_033289 /// NM_033290 /// NM_033291 /// XM_005274536 /// XM_005274537 /// XM_005274538 /// XM_006724492 /// XM_006724493 /// XR_247298 /// XR_247299 /// XR_247300 /// XR_250630 /// XR_250631 /// XR_250632 /// XR_254127 /// XR_254128 /// XR_254129 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 203638_s_at NM_022969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022969.1 /DEF=Homo sapiens fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) (FGFR2), transcript variant 2, mRNA. /FEA=mRNA /GEN=FGFR2 /PROD=fibroblast growth factor receptor 2, isoform 2precursor /DB_XREF=gi:13186252 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022969.1 gb:M97193.1 gb:M80634.1 NM_022969 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203639_s_at M80634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80634.1 /DEF=Human keratinocyte growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=keratinocyte growth factor receptor /DB_XREF=gi:186740 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022969.1 gb:M97193.1 gb:M80634.1 M80634 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203640_at BE328496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE328496 /FEA=EST /DB_XREF=gi:9202272 /DB_XREF=est:hs98f09.x1 /CLONE=IMAGE:3145289 /UG=Hs.283609 hypothetical protein PRO2032 /FL=gb:AF116683.1 gb:NM_018615.1 BE328496 muscleblind-like splicing regulator 2 MBNL2 10150 NM_144778 /// NM_207304 /// XM_005254018 /// XM_005254019 /// XM_005254020 /// XM_005254021 /// XM_005254022 /// XM_006719912 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203641_s_at BF002844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002844 /FEA=EST /DB_XREF=gi:10703119 /DB_XREF=est:7g49h05.x1 /CLONE=IMAGE:3309849 /UG=Hs.300855 KIAA0977 protein /FL=gb:AB023194.1 gb:NM_014900.1 BF002844 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 203642_s_at NM_014900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014900.1 /DEF=Homo sapiens KIAA0977 protein (KIAA0977), mRNA. /FEA=mRNA /GEN=KIAA0977 /PROD=KIAA0977 protein /DB_XREF=gi:7662427 /UG=Hs.300855 KIAA0977 protein /FL=gb:AB023194.1 gb:NM_014900.1 NM_014900 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 203643_at NM_006494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006494.1 /DEF=Homo sapiens Ets2 repressor factor (ERF), mRNA. /FEA=mRNA /GEN=ERF /PROD=Ets2 repressor factor /DB_XREF=gi:5729813 /UG=Hs.333069 Ets2 repressor factor /FL=gb:U15655.1 gb:NM_006494.1 NM_006494 Ets2 repressor factor ERF 2077 NM_006494 /// XM_005258643 /// XM_005258644 /// XM_006723079 /// XM_006723080 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007049 // cell cycle // non-traceable author statement /// 0010668 // ectodermal cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203644_s_at AI629033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI629033 /FEA=EST /DB_XREF=gi:4665833 /DB_XREF=est:ty79g04.x1 /CLONE=IMAGE:2285334 /UG=Hs.40109 KIAA0872 protein /FL=gb:AB020679.1 gb:NM_014940.1 AI629033 MON1 secretory trafficking family member B MON1B 22879 NM_001286639 /// NM_001286640 /// NM_014940 0005515 // protein binding // inferred from physical interaction 203645_s_at NM_004244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004244.1 /DEF=Homo sapiens CD163 antigen (CD163), mRNA. /FEA=mRNA /GEN=CD163 /PROD=CD163 antigen /DB_XREF=gi:4758721 /UG=Hs.74076 CD163 antigen /FL=gb:NM_004244.1 NM_004244 CD163 molecule CD163 9332 NM_004244 /// NM_203416 /// XM_005253528 /// XM_005253529 /// XR_429039 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005044 // scavenger receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203646_at NM_004109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004109.2 /DEF=Homo sapiens ferredoxin 1 (FDX1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FDX1 /PROD=ferredoxin 1 precursor /DB_XREF=gi:13677224 /UG=Hs.744 ferredoxin 1 /FL=gb:NM_004109.2 gb:J03548.1 gb:M18003.1 gb:M34788.1 NM_004109 ferredoxin 1 FDX1 2230 NM_004109 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0005506 // iron ion binding // traceable author statement /// 0009055 // electron carrier activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay 203647_s_at M18003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M18003.1 /DEF=Human ferredoxin mRNA, complete cds. /FEA=mRNA /PROD=ferredoxin /DB_XREF=gi:182493 /UG=Hs.744 ferredoxin 1 /FL=gb:NM_004109.2 gb:J03548.1 gb:M18003.1 gb:M34788.1 M18003 ferredoxin 1 FDX1 2230 NM_004109 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0005506 // iron ion binding // traceable author statement /// 0009055 // electron carrier activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay 203648_at NM_014760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014760.1 /DEF=Homo sapiens KIAA0218 gene product (KIAA0218), mRNA. /FEA=mRNA /GEN=KIAA0218 /PROD=KIAA0218 gene product /DB_XREF=gi:7662007 /UG=Hs.75863 KIAA0218 gene product /FL=gb:D86972.1 gb:NM_014760.1 NM_014760 TatD DNase domain containing 2 TATDN2 9797 NM_014760 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006308 // DNA catabolic process // not recorded /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0043229 // intracellular organelle // not recorded 0004518 // nuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203649_s_at NM_000300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000300.1 /DEF=Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PLA2G2A /PROD=phospholipase A2, group IIA (platelets, synovialfluid) /DB_XREF=gi:4505848 /UG=Hs.76422 phospholipase A2, group IIA (platelets, synovial fluid) /FL=gb:M22430.1 gb:NM_000300.1 NM_000300 phospholipase A2, group IIA (platelets, synovial fluid) PLA2G2A 5320 NM_000300 /// NM_001161727 /// NM_001161728 /// NM_001161729 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046473 // phosphatidic acid metabolic process // inferred from direct assay /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0004623 // phospholipase A2 activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // traceable author statement 203650_at NM_006404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006404.1 /DEF=Homo sapiens protein C receptor, endothelial (EPCR) (PROCR), mRNA. /FEA=mRNA /GEN=PROCR /PROD=protein C receptor, endothelial (EPCR) /DB_XREF=gi:5453645 /UG=Hs.82353 protein C receptor, endothelial (EPCR) /FL=gb:NM_006404.1 gb:L35545.1 NM_006404 protein C receptor, endothelial PROCR 10544 NM_006404 /// XM_005260251 /// XM_006723682 0006955 // immune response // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0050819 // negative regulation of coagulation // inferred from mutant phenotype 0005813 // centrosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203651_at NM_014733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014733.1 /DEF=Homo sapiens KIAA0305 gene product (KIAA0305), mRNA. /FEA=mRNA /GEN=KIAA0305 /PROD=KIAA0305 gene product /DB_XREF=gi:7662047 /UG=Hs.83790 KIAA0305 gene product /FL=gb:AB002303.1 gb:NM_014733.1 NM_014733 zinc finger, FYVE domain containing 16 ZFYVE16 9765 NM_001105251 /// NM_001284236 /// NM_001284237 /// NM_014733 /// XM_005248632 /// XM_005248634 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0016050 // vesicle organization // non-traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // traceable author statement /// 0030509 // BMP signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 203652_at NM_002419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002419.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 11 (MAP3K11), mRNA. /FEA=mRNA /GEN=MAP3K11 /PROD=mitogen-activated protein kinase kinase kinase11 /DB_XREF=gi:4505194 /UG=Hs.89449 mitogen-activated protein kinase kinase kinase 11 /FL=gb:NM_002419.1 gb:U07747.1 gb:L32976.1 NM_002419 mitogen-activated protein kinase kinase kinase 11 MAP3K11 4296 NM_002419 /// XR_428915 0000080 // mitotic G1 phase // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007017 // microtubule-based process // inferred from mutant phenotype /// 0007254 // JNK cascade // traceable author statement /// 0007256 // activation of JNKK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004706 // JUN kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048365 // Rac GTPase binding // inferred from electronic annotation 203653_s_at BG391060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG391060 /FEA=EST /DB_XREF=gi:13284508 /DB_XREF=est:602417755F1 /CLONE=IMAGE:4537164 /UG=Hs.966 coilin /FL=gb:U06632.1 gb:NM_004645.1 BG391060 coilin COIL 8161 NM_004645 0055114 // oxidation-reduction process // inferred from electronic annotation 0001674 // female germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0015036 // disulfide oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203654_s_at NM_004645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004645.1 /DEF=Homo sapiens coilin (COIL), mRNA. /FEA=mRNA /GEN=COIL /PROD=coilin /DB_XREF=gi:4758023 /UG=Hs.966 coilin /FL=gb:U06632.1 gb:NM_004645.1 NM_004645 coilin COIL 8161 NM_004645 0055114 // oxidation-reduction process // inferred from electronic annotation 0001674 // female germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0015036 // disulfide oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203655_at NM_006297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006297.1 /DEF=Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1), mRNA. /FEA=mRNA /GEN=XRCC1 /PROD=X-ray repair cross complementing protein 1 /DB_XREF=gi:5454171 /UG=Hs.98493 X-ray repair complementing defective repair in Chinese hamster cells 1 /FL=gb:M36089.1 gb:NM_006297.1 NM_006297 X-ray repair complementing defective repair in Chinese hamster cells 1 XRCC1 7515 NM_006297 0000012 // single strand break repair // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006284 // base-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203656_at NM_014845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014845.1 /DEF=Homo sapiens KIAA0274 gene product (KIAA0274), mRNA. /FEA=mRNA /GEN=KIAA0274 /PROD=KIAA0274 gene product /DB_XREF=gi:7662033 /UG=Hs.10037 KIAA0274 gene product /FL=gb:D87464.1 gb:NM_014845.1 NM_014845 FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) FIG4 9896 NM_014845 /// XM_006715622 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007033 // vacuole organization // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043473 // pigmentation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034593 // phosphatidylinositol bisphosphate phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0043812 // phosphatidylinositol-4-phosphate phosphatase activity // inferred from electronic annotation /// 0043813 // phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity // traceable author statement 203657_s_at NM_003793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003793.2 /DEF=Homo sapiens cathepsin F (CTSF), mRNA. /FEA=mRNA /GEN=CTSF /PROD=cathepsin F /DB_XREF=gi:6042195 /UG=Hs.11590 cathepsin F /FL=gb:AF071748.1 gb:AF071749.1 gb:AF088886.2 gb:NM_003793.2 gb:AF136279.1 NM_003793 cathepsin F CTSF 8722 NM_003793 0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203658_at BC001689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001689.1 /DEF=Homo sapiens, carnitineacylcarnitine translocase, clone MGC:1207, mRNA, complete cds. /FEA=mRNA /PROD=carnitineacylcarnitine translocase /DB_XREF=gi:12804552 /UG=Hs.13845 solute carrier family 25 (carnitineacylcarnitine translocase), member 20 /FL=gb:BC001689.1 gb:NM_000387.2 BC001689 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 SLC25A20 788 NM_000387 /// XM_006713327 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203659_s_at NM_005798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005798.1 /DEF=Homo sapiens ret finger protein 2 (RFP2), mRNA. /FEA=mRNA /GEN=RFP2 /PROD=ret finger protein 2 /DB_XREF=gi:5031860 /UG=Hs.151428 ret finger protein 2 /FL=gb:AF220127.1 gb:AF220128.1 gb:NM_005798.1 gb:AF241850.1 NM_005798 tripartite motif containing 13 TRIM13 10206 NM_001007278 /// NM_005798 /// NM_052811 /// NM_213590 0007165 // signal transduction // inferred from mutant phenotype /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010332 // response to gamma radiation // inferred from expression pattern /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016239 // positive regulation of macroautophagy // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203660_s_at NM_006031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006031.1 /DEF=Homo sapiens pericentrin (PCNT), mRNA. /FEA=mRNA /GEN=PCNT /PROD=pericentrin /DB_XREF=gi:5174478 /UG=Hs.15896 pericentrin /FL=gb:U52962.1 gb:NM_006031.1 NM_006031 pericentrin PCNT 5116 NM_006031 /// XM_005261124 /// XM_005261125 /// XM_005261126 /// XM_005261127 /// XM_005261128 /// XM_005261129 /// XM_005261130 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007051 // spindle organization // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0045171 // intercellular bridge // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 203661_s_at BC002660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002660.1 /DEF=Homo sapiens, tropomodulin, clone MGC:3643, mRNA, complete cds. /FEA=mRNA /PROD=tropomodulin /DB_XREF=gi:12803650 /UG=Hs.170453 tropomodulin /FL=gb:BC002660.1 gb:M77016.1 gb:NM_003275.1 BC002660 tropomodulin 1 TMOD1 7111 NM_001166116 /// NM_003275 0006936 // muscle contraction // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203662_s_at NM_003275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003275.1 /DEF=Homo sapiens tropomodulin (TMOD), mRNA. /FEA=mRNA /GEN=TMOD /PROD=tropomodulin /DB_XREF=gi:4507552 /UG=Hs.170453 tropomodulin /FL=gb:BC002660.1 gb:M77016.1 gb:NM_003275.1 NM_003275 tropomodulin 1 TMOD1 7111 NM_001166116 /// NM_003275 0006936 // muscle contraction // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203663_s_at NM_004255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004255.1 /DEF=Homo sapiens cytochrome c oxidase subunit Va (COX5A), mRNA. /FEA=mRNA /GEN=COX5A /PROD=cytochrome c oxidase subunit Va /DB_XREF=gi:4758037 /UG=Hs.181028 cytochrome c oxidase subunit Va /FL=gb:NM_004255.1 gb:M22760.1 NM_004255 cytochrome c oxidase subunit Va COX5A 9377 NM_004255 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203664_s_at NM_004805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004805.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide D (POLR2D), mRNA. /FEA=mRNA /GEN=POLR2D /PROD=polymerase (RNA) II (DNA directed) polypeptideD /DB_XREF=gi:4758573 /UG=Hs.194638 polymerase (RNA) II (DNA directed) polypeptide D /FL=gb:BC002958.1 gb:NM_004805.1 NM_004805 polymerase (RNA) II (DNA directed) polypeptide D POLR2D 5433 NM_004805 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // not recorded /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0031990 // mRNA export from nucleus in response to heat stress // not recorded /// 0034402 // recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex // not recorded /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // not recorded /// 0050434 // positive regulation of viral transcription // traceable author statement 0000932 // cytoplasmic mRNA processing body // not recorded /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // not recorded /// 0003727 // single-stranded RNA binding // not recorded /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // not recorded 203665_at NM_002133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002133.1 /DEF=Homo sapiens heme oxygenase (decycling) 1 (HMOX1), mRNA. /FEA=mRNA /GEN=HMOX1 /PROD=heme oxygenase (decyclizing) 1 /DB_XREF=gi:4504436 /UG=Hs.202833 heme oxygenase (decycling) 1 /FL=gb:NM_002133.1 NM_002133 heme oxygenase (decycling) 1 HMOX1 3162 NM_002133 0001525 // angiogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // traceable author statement /// 0002246 // wound healing involved in inflammatory response // inferred from mutant phenotype /// 0002686 // negative regulation of leukocyte migration // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006788 // heme oxidation // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007588 // excretion // inferred by curator /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014806 // smooth muscle hyperplasia // traceable author statement /// 0031670 // cellular response to nutrient // inferred from electronic annotation /// 0032764 // negative regulation of mast cell cytokine production // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0042167 // heme catabolic process // inferred from direct assay /// 0042167 // heme catabolic process // traceable author statement /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043305 // negative regulation of mast cell degranulation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045080 // positive regulation of chemokine biosynthetic process // traceable author statement /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred by curator /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071243 // cellular response to arsenic-containing substance // inferred from electronic annotation /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004392 // heme oxygenase (decyclizing) activity // inferred from direct assay /// 0004392 // heme oxygenase (decyclizing) activity // inferred from mutant phenotype /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203666_at NM_000609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000609.1 /DEF=Homo sapiens stromal cell-derived factor 1 (SDF1), mRNA. /FEA=mRNA /GEN=SDF1 /PROD=stromal cell-derived factor 1 /DB_XREF=gi:10834987 /UG=Hs.237356 stromal cell-derived factor 1 /FL=gb:NM_000609.1 gb:L36033.1 gb:U16752.1 NM_000609 chemokine (C-X-C motif) ligand 12 CXCL12 6387 NM_000609 /// NM_001033886 /// NM_001178134 /// NM_001277990 /// NM_199168 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from mutant phenotype /// 0045236 // CXCR chemokine receptor binding // inferred from direct assay 203667_at NM_004607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004607.1 /DEF=Homo sapiens tubulin-specific chaperone a (TBCA), mRNA. /FEA=mRNA /GEN=TBCA /PROD=beta-tubulin cofactor A /DB_XREF=gi:4759211 /UG=Hs.24930 tubulin-specific chaperone a /FL=gb:AF038952.1 gb:NM_004607.1 NM_004607 tubulin folding cofactor A TBCA 6902 NM_004607 /// XM_005248586 0006457 // protein folding // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0007023 // post-chaperonin tubulin folding pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203668_at NM_006715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006715.1 /DEF=Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), mRNA. /FEA=mRNA /GEN=MAN2C1 /PROD=mannosidase, alpha 6A8 /DB_XREF=gi:6631092 /UG=Hs.26232 mannosidase, alpha, class 2C, member 1 /FL=gb:U37248.1 gb:AF044414.2 gb:NM_006715.1 NM_006715 mannosidase, alpha, class 2C, member 1 MAN2C1 4123 NM_001256494 /// NM_001256495 /// NM_001256496 /// NM_006715 /// XM_005254384 /// XM_006720508 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203669_s_at NM_012079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012079.2 /DEF=Homo sapiens diacylglycerol O-acyltransferase (mouse) homolog (DGAT), mRNA. /FEA=mRNA /GEN=DGAT /PROD=diacylglycerol O-acyltransferase (mouse)homolog /DB_XREF=gi:7382489 /UG=Hs.288627 diacylglycerol O-acyltransferase (mouse) homolog /FL=gb:AF059202.1 gb:NM_012079.2 NM_012079 diacylglycerol O-acyltransferase 1 DGAT1 8694 NM_012079 0006641 // triglyceride metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0035336 // long-chain fatty-acyl-CoA metabolic process // inferred from sequence or structural similarity /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046339 // diacylglycerol metabolic process // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003846 // 2-acylglycerol O-acyltransferase activity // inferred from electronic annotation /// 0004144 // diacylglycerol O-acyltransferase activity // not recorded /// 0004144 // diacylglycerol O-acyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050252 // retinol O-fatty-acyltransferase activity // inferred from electronic annotation 203670_at NM_015644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015644.1 /DEF=Homo sapiens DKFZP434B103 protein (DKFZP434B103), mRNA. /FEA=mRNA /GEN=DKFZP434B103 /PROD=DKFZP434B103 protein /DB_XREF=gi:7661563 /UG=Hs.289010 DKFZP434B103 protein /FL=gb:NM_015644.1 NM_015644 actin related protein 2/3 complex, subunit 4, 20kDa /// ARPC4-TTLL3 readthrough /// tubulin tyrosine ligase-like family, member 3 ARPC4 /// ARPC4-TTLL3 /// TTLL3 10093 /// 26140 /// 100526693 NM_001024959 /// NM_001024960 /// NM_001025930 /// NM_001198780 /// NM_001198793 /// NM_005718 /// NM_015644 /// NR_037162 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0018094 // protein polyglycylation // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0035082 // axoneme assembly // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement /// 0070735 // protein-glycine ligase activity // inferred from direct assay /// 0070736 // protein-glycine ligase activity, initiating // inferred from sequence or structural similarity 203671_at BF196891 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196891 /FEA=EST /DB_XREF=gi:11085421 /DB_XREF=est:7l79g03.x1 /CLONE=IMAGE:3527621 /UG=Hs.296922 thiopurine S-methyltransferase /FL=gb:BC005339.1 gb:NM_000367.1 gb:U12387.1 BF196891 thiopurine S-methyltransferase TPMT 7172 NM_000367 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008119 // thiopurine S-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203672_x_at U12387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U12387.1 /DEF=Human thiopurine methyltransferase (TPMT) mRNA, complete cds. /FEA=mRNA /GEN=TPMT /PROD=thiopurine methyltransferase /DB_XREF=gi:805083 /UG=Hs.296922 thiopurine S-methyltransferase /FL=gb:BC005339.1 gb:NM_000367.1 gb:U12387.1 U12387 thiopurine S-methyltransferase TPMT 7172 NM_000367 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008119 // thiopurine S-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203673_at NM_003235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003235.2 /DEF=Homo sapiens thyroglobulin (TG), mRNA. /FEA=mRNA /GEN=TG /PROD=thyroglobulin /DB_XREF=gi:6631113 /UG=Hs.305916 thyroglobulin /FL=gb:U93033.2 gb:NM_003235.2 NM_003235 thyroglobulin TG 7038 NM_003235 /// XM_005251038 /// XM_005251040 /// XM_005251042 /// XM_005251043 /// XM_006716622 /// XM_006716623 0006590 // thyroid hormone generation // not recorded /// 0007165 // signal transduction // non-traceable author statement /// 0007416 // synapse assembly // not recorded /// 0015705 // iodide transport // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0042403 // thyroid hormone metabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005887 // integral component of plasma membrane // not recorded /// 0009986 // cell surface // not recorded /// 0045202 // synapse // not recorded 0004872 // receptor activity // not recorded /// 0005179 // hormone activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // not recorded 203674_at NM_014877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014877.1 /DEF=Homo sapiens KIAA0054 gene product; Helicase (KIAA0054), mRNA. /FEA=mRNA /GEN=KIAA0054 /PROD=KIAA0054 gene product; Helicase /DB_XREF=gi:7661883 /UG=Hs.3085 KIAA0054 gene product; Helicase /FL=gb:D29677.1 gb:NM_014877.1 NM_014877 helicase with zinc finger HELZ 9931 NM_014877 /// XM_005257888 /// XM_005257889 /// XM_005257890 /// XM_006722214 /// XM_006722215 /// XM_006722216 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203675_at NM_005013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005013.1 /DEF=Homo sapiens nucleobindin 2 (NUCB2), mRNA. /FEA=mRNA /GEN=NUCB2 /PROD=nucleobindin 2 /DB_XREF=gi:4826869 /UG=Hs.3164 nucleobindin 2 /FL=gb:AF052642.1 gb:AF052643.1 gb:AF052644.1 gb:NM_005013.1 NM_005013 nucleobindin 2 NUCB2 4925 NM_005013 /// XM_005252941 /// XM_005252942 /// XM_005252943 /// XM_005252944 /// XM_005252945 /// XM_005252947 /// XM_005252948 /// XM_006718239 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203676_at NM_002076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002076.1 /DEF=Homo sapiens glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) (GNS), mRNA. /FEA=mRNA /GEN=GNS /PROD=glucosamine (N-acetyl)-6-sulfatase precursor /DB_XREF=gi:4504060 /UG=Hs.321070 glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) /FL=gb:NM_002076.1 NM_002076 glucosamine (N-acetyl)-6-sulfatase GNS 2799 NM_002076 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203677_s_at NM_004178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004178.2 /DEF=Homo sapiens TAR (HIV) RNA-binding protein 2 (TARBP2), mRNA. /FEA=mRNA /GEN=TARBP2 /PROD=TAR (HIV) RNA-binding protein 2 /DB_XREF=gi:7427525 /UG=Hs.326 TAR (HIV) RNA-binding protein 2 /FL=gb:U08998.2 gb:NM_004178.2 NM_004178 TAR (HIV-1) RNA binding protein 2 TARBP2 6895 NM_004178 /// NM_134323 /// NM_134324 /// XM_005269114 /// XM_005269115 /// XM_005269116 /// XM_005269117 /// XM_005269120 /// XM_005269122 /// XM_006719581 /// XR_245955 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0035280 // miRNA loading onto RISC involved in gene silencing by miRNA // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0046782 // regulation of viral transcription // inferred from direct assay /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 203678_at NM_014967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014967.1 /DEF=Homo sapiens KIAA1018 protein (KIAA1018), mRNA. /FEA=mRNA /GEN=KIAA1018 /PROD=KIAA1018 protein /DB_XREF=gi:7662449 /UG=Hs.5400 KIAA1018 protein /FL=gb:AB023235.1 gb:NM_014967.1 NM_014967 FANCD2/FANCI-associated nuclease 1 FAN1 22909 NM_001146094 /// NM_001146095 /// NM_001146096 /// NM_014967 /// XM_005254232 /// XM_005254233 /// XM_005254234 /// XM_005254235 /// XM_005254236 /// XM_006725537 /// XM_006725538 /// XM_006725539 /// XM_006725540 /// XM_006725541 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0033683 // nucleotide-excision repair, DNA incision // inferred from direct assay /// 0033683 // nucleotide-excision repair, DNA incision // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0000287 // magnesium ion binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203679_at NM_006858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006858.1 /DEF=Homo sapiens putative T1ST2 receptor binding protein (IL1RL1LG), mRNA. /FEA=mRNA /GEN=IL1RL1LG /PROD=putative T1ST2 receptor binding protein /DB_XREF=gi:5803039 /UG=Hs.54411 putative T1ST2 receptor binding protein /FL=gb:U41804.1 gb:BC002443.1 gb:NM_006858.1 NM_006858 transmembrane emp24 protein transport domain containing 1 TMED1 11018 NM_006858 /// NR_104015 /// XM_006722631 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203680_at NM_002736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002736.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), mRNA. /FEA=mRNA /GEN=PRKAR2B /PROD=protein kinase, cAMP-dependent, regulatory, typeII, beta /DB_XREF=gi:4506064 /UG=Hs.77439 protein kinase, cAMP-dependent, regulatory, type II, beta /FL=gb:M31158.1 gb:NM_002736.1 NM_002736 protein kinase, cAMP-dependent, regulatory, type II, beta PRKAR2B 5577 NM_002736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097332 // response to antipsychotic drug // inferred from electronic annotation /// 0097338 // response to clozapine // inferred from electronic annotation /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 203681_at M34192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M34192.1 /DEF=Human isovaleryl-coA dehydrogenase (IVD) mRNA, complete cds. /FEA=mRNA /GEN=IVD /DB_XREF=gi:184538 /UG=Hs.77510 isovaleryl Coenzyme A dehydrogenase /FL=gb:M34192.1 gb:NM_002225.2 M34192 isovaleryl-CoA dehydrogenase IVD 3712 NM_001159508 /// NM_002225 /// XM_005254350 /// XM_005254356 /// XM_006720491 /// XM_006720492 /// XM_006720493 /// XM_006720494 /// XM_006720495 /// XR_243097 /// XR_243098 /// XR_429453 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0008470 // isovaleryl-CoA dehydrogenase activity // not recorded /// 0008470 // isovaleryl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 203682_s_at NM_002225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002225.2 /DEF=Homo sapiens isovaleryl Coenzyme A dehydrogenase (IVD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=IVD /PROD=isovaleryl Coenzyme A dehydrogenase /DB_XREF=gi:6031167 /UG=Hs.77510 isovaleryl Coenzyme A dehydrogenase /FL=gb:M34192.1 gb:NM_002225.2 NM_002225 isovaleryl-CoA dehydrogenase IVD 3712 NM_001159508 /// NM_002225 /// XM_005254350 /// XM_005254356 /// XM_006720491 /// XM_006720492 /// XM_006720493 /// XM_006720494 /// XM_006720495 /// XR_243097 /// XR_243098 /// XR_429453 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0008470 // isovaleryl-CoA dehydrogenase activity // not recorded /// 0008470 // isovaleryl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 203683_s_at NM_003377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003377.1 /DEF=Homo sapiens vascular endothelial growth factor B (VEGFB), mRNA. /FEA=mRNA /GEN=VEGFB /PROD=vascular endothelial growth factor B /DB_XREF=gi:4507886 /UG=Hs.78781 vascular endothelial growth factor B /FL=gb:U43368.1 gb:U52819.1 gb:NM_003377.1 NM_003377 vascular endothelial growth factor B VEGFB 7423 NM_001243733 /// NM_003377 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0035470 // positive regulation of vascular wound healing // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060976 // coronary vasculature development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203684_s_at M13994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13994.1 /DEF=Human B-cell leukemialymphoma 2 (bcl-2) proto-oncogene mRNA encoding bcl-2-alpha protein, complete cds. /FEA=mRNA /GEN=BCL2 /DB_XREF=gi:179366 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13994.1 gb:NM_000633.1 M13994 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 203685_at NM_000633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000633.1 /DEF=Homo sapiens B-cell CLLlymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant alpha, mRNA. /FEA=mRNA /GEN=BCL2 /PROD=B-cell lymphoma protein 2 alpha /DB_XREF=gi:4557354 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13994.1 gb:NM_000633.1 NM_000633 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 203686_at NM_002434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002434.1 /DEF=Homo sapiens N-methylpurine-DNA glycosylase (MPG), mRNA. /FEA=mRNA /GEN=MPG /PROD=N-methylpurine-DNA glycosylase /DB_XREF=gi:4505232 /UG=Hs.79396 N-methylpurine-DNA glycosylase /FL=gb:M74905.1 gb:L10752.1 gb:NM_002434.1 NM_002434 N-methylpurine-DNA glycosylase MPG 4350 NM_001015052 /// NM_001015054 /// NM_002434 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006307 // DNA dealkylation involved in DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045007 // depurination // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003905 // alkylbase DNA N-glycosylase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008725 // DNA-3-methyladenine glycosylase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043916 // DNA-7-methylguanine glycosylase activity // inferred from electronic annotation /// 0052821 // DNA-7-methyladenine glycosylase activity // inferred from electronic annotation /// 0052822 // DNA-3-methylguanine glycosylase activity // inferred from electronic annotation 203687_at NM_002996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002996.1 /DEF=Homo sapiens small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) (SCYD1), mRNA. /FEA=mRNA /GEN=SCYD1 /PROD=small inducible cytokine subfamily D(Cys-X3-Cys), member 1 (fractalkine, neurotactin) /DB_XREF=gi:4506856 /UG=Hs.80420 small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) /FL=gb:BC001163.1 gb:U84487.1 gb:U91835.1 gb:NM_002996.1 NM_002996 chemokine (C-X3-C motif) ligand 1 CX3CL1 6376 NM_002996 0006935 // chemotaxis // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // traceable author statement /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0048247 // lymphocyte chemotaxis // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from expression pattern /// 0050902 // leukocyte adhesive activation // traceable author statement /// 0051041 // positive regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // traceable author statement 203688_at NM_000297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000297.1 /DEF=Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA. /FEA=mRNA /GEN=PKD2 /PROD=polycystin 2 /DB_XREF=gi:4505834 /UG=Hs.82001 polycystic kidney disease 2 (autosomal dominant) /FL=gb:U50928.1 gb:NM_000297.1 NM_000297 polycystic kidney disease 2 (autosomal dominant) PKD2 5311 NM_000297 /// XR_244632 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from expression pattern /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from mutant phenotype /// 0003127 // detection of nodal flow // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0030814 // regulation of cAMP metabolic process // inferred from sequence or structural similarity /// 0031587 // positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // non-traceable author statement /// 0035502 // metanephric part of ureteric bud development // inferred from expression pattern /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035904 // aorta development // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from mutant phenotype /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051298 // centrosome duplication // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0061441 // renal artery morphogenesis // inferred from expression pattern /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0071464 // cellular response to hydrostatic pressure // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071498 // cellular response to fluid shear stress // inferred from mutant phenotype /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype /// 0072001 // renal system development // inferred from electronic annotation /// 0072075 // metanephric mesenchyme development // inferred from expression pattern /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072208 // metanephric smooth muscle tissue development // inferred from expression pattern /// 0072214 // metanephric cortex development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072219 // metanephric cortical collecting duct development // inferred from expression pattern /// 0072235 // metanephric distal tubule development // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from sequence or structural similarity /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045180 // basal cortex // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071458 // integral component of cytoplasmic side of endoplasmic reticulum membrane // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from direct assay /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015267 // channel activity // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042805 // actinin binding // inferred from direct assay /// 0043398 // HLH domain binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048763 // calcium-induced calcium release activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from electronic annotation 203689_s_at AI743037 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743037 /FEA=EST /DB_XREF=gi:5111325 /DB_XREF=est:wg85d05.x1 /CLONE=IMAGE:2371881 /UG=Hs.89764 fragile X mental retardation 1 /FL=gb:NM_002024.1 AI743037 fragile X mental retardation 1 FMR1 2332 NM_001185075 /// NM_001185076 /// NM_001185081 /// NM_001185082 /// NM_002024 /// NR_033699 /// NR_033700 0006810 // transport // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042788 // polysomal ribosome // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203690_at NM_006322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006322.1 /DEF=Homo sapiens spindle pole body protein (GCP3), mRNA. /FEA=mRNA /GEN=GCP3 /PROD=spindle pole body protein /DB_XREF=gi:5453659 /UG=Hs.9884 spindle pole body protein /FL=gb:AF042378.1 gb:NM_006322.1 NM_006322 tubulin, gamma complex associated protein 3 TUBGCP3 10426 NM_001286277 /// NM_001286278 /// NM_001286279 /// NM_006322 /// XM_005268293 /// XR_245841 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007338 // single fertilization // non-traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // non-traceable author statement /// 0005827 // polar microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from direct assay 203691_at NM_002638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002638.1 /DEF=Homo sapiens protease inhibitor 3, skin-derived (SKALP) (PI3), mRNA. /FEA=mRNA /GEN=PI3 /PROD=protease inhibitor 3, skin-derived (SKALP) /DB_XREF=gi:4505786 /UG=Hs.112341 protease inhibitor 3, skin-derived (SKALP) /FL=gb:NM_002638.1 NM_002638 peptidase inhibitor 3, skin-derived PI3 5266 NM_002638 0007620 // copulation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203692_s_at AI640363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI640363 /FEA=EST /DB_XREF=gi:4703472 /DB_XREF=est:wa17d03.x1 /CLONE=IMAGE:2298341 /UG=Hs.1189 E2F transcription factor 3 /FL=gb:NM_001949.2 AI640363 E2F transcription factor 3 E2F3 1871 NM_001243076 /// NM_001949 /// XM_005248865 /// XM_005248866 /// XM_005248868 0000085 // mitotic G2 phase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203693_s_at NM_001949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001949.2 /DEF=Homo sapiens E2F transcription factor 3 (E2F3) mRNA, complete cds. /FEA=mRNA /GEN=E2F3 /PROD=E2F transcription factor 3 /DB_XREF=gi:12669913 /UG=Hs.1189 E2F transcription factor 3 /FL=gb:NM_001949.2 NM_001949 E2F transcription factor 3 E2F3 1871 NM_001243076 /// NM_001949 /// XM_005248865 /// XM_005248866 /// XM_005248868 0000085 // mitotic G2 phase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203694_s_at NM_003587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003587.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 (DDX16), mRNA. /FEA=mRNA /GEN=DDX16 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 /DB_XREF=gi:13787201 /UG=Hs.12797 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 /FL=gb:NM_003587.2 gb:AB011149.1 gb:AB001601.1 NM_003587 DEAH (Asp-Glu-Ala-His) box polypeptide 16 DHX16 8449 NM_001164239 /// NM_003587 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203695_s_at NM_004403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004403.1 /DEF=Homo sapiens deafness, autosomal dominant 5 (DFNA5), mRNA. /FEA=mRNA /GEN=DFNA5 /PROD=deafness, autosomal dominant 5 protein /DB_XREF=gi:4758153 /UG=Hs.13530 deafness, autosomal dominant 5 /FL=gb:AF073308.1 gb:NM_004403.1 gb:AF007790.2 NM_004403 deafness, autosomal dominant 5 DFNA5 1687 NM_001127453 /// NM_001127454 /// NM_004403 0006915 // apoptotic process // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 203696_s_at NM_002914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002914.1 /DEF=Homo sapiens replication factor C (activator 1) 2 (40kD) (RFC2), mRNA. /FEA=mRNA /GEN=RFC2 /PROD=replication factor C (activator 1) 2 (40kD) /DB_XREF=gi:4506486 /UG=Hs.139226 replication factor C (activator 1) 2 (40kD) /FL=gb:M87338.1 gb:NM_002914.1 NM_002914 replication factor C (activator 1) 2, 40kDa RFC2 5982 NM_001278791 /// NM_001278792 /// NM_001278793 /// NM_002914 /// NM_181471 /// XM_006716080 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203697_at U91903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U91903.1 /DEF=Human Fritz mRNA, complete cds. /FEA=mRNA /PROD=Fritz /DB_XREF=gi:1917006 /UG=Hs.153684 frizzled-related protein /FL=gb:U24163.1 gb:U68057.1 gb:U91903.1 gb:NM_001463.1 U91903 frizzled-related protein FRZB 2487 NM_001463 0001501 // skeletal system development // traceable author statement /// 0001944 // vasculature development // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0010721 // negative regulation of cell development // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0061037 // negative regulation of cartilage development // not recorded /// 0061053 // somite development // inferred from electronic annotation /// 0070367 // negative regulation of hepatocyte differentiation // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0016020 // membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 203698_s_at NM_001463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001463.1 /DEF=Homo sapiens frizzled-related protein (FRZB), mRNA. /FEA=mRNA /GEN=FRZB /PROD=frizzled-related protein /DB_XREF=gi:4503788 /UG=Hs.153684 frizzled-related protein /FL=gb:U24163.1 gb:U68057.1 gb:U91903.1 gb:NM_001463.1 NM_001463 frizzled-related protein FRZB 2487 NM_001463 0001501 // skeletal system development // traceable author statement /// 0001944 // vasculature development // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0010721 // negative regulation of cell development // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0061037 // negative regulation of cartilage development // not recorded /// 0061053 // somite development // inferred from electronic annotation /// 0070367 // negative regulation of hepatocyte differentiation // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0016020 // membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 203699_s_at U53506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U53506.1 /DEF=Human type II iodothyronine deiodinase mRNA, complete cds. /FEA=mRNA /PROD=type II iodothyronine deiodinase /DB_XREF=gi:1518541 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:U53506.1 gb:AF093774.1 gb:NM_013989.1 U53506 deiodinase, iodothyronine, type II DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203700_s_at NM_013989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013989.1 /DEF=Homo sapiens deiodinase, iodothyronine, type II (DIO2), transcript variant 1, mRNA. /FEA=mRNA /GEN=DIO2 /PROD=deiodinase, iodothyronine, type II /DB_XREF=gi:7549802 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:U53506.1 gb:AF093774.1 gb:NM_013989.1 NM_013989 deiodinase, iodothyronine, type II DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203701_s_at NM_017722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017722.1 /DEF=Homo sapiens hypothetical protein FLJ20244 (FLJ20244), mRNA. /FEA=mRNA /GEN=FLJ20244 /PROD=hypothetical protein FLJ20244 /DB_XREF=gi:8923218 /UG=Hs.158947 hypothetical protein FLJ20244 /FL=gb:AF196479.1 gb:NM_017722.1 NM_017722 tRNA methyltransferase 1 homolog (S. cerevisiae) TRMT1 55621 NM_001136035 /// NM_001142554 /// NM_017722 /// XM_005259983 /// XM_006722793 /// XM_006722794 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004809 // tRNA (guanine-N2-)-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203702_s_at AL043927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043927 /FEA=EST /DB_XREF=gi:5935917 /DB_XREF=est:DKFZp434F1028_s1 /CLONE=DKFZp434F1028 /UG=Hs.169910 KIAA0173 gene product /FL=gb:D79995.1 gb:NM_014640.1 AL043927 tubulin tyrosine ligase-like family, member 4 TTLL4 9654 NM_014640 /// XM_005246977 /// XM_005246978 /// XM_006712873 /// XM_006712874 /// XM_006712875 /// XM_006712876 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016874 // ligase activity // inferred from electronic annotation 203703_s_at NM_014640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014640.1 /DEF=Homo sapiens KIAA0173 gene product (KIAA0173), mRNA. /FEA=mRNA /GEN=KIAA0173 /PROD=KIAA0173 gene product /DB_XREF=gi:7661969 /UG=Hs.169910 KIAA0173 gene product /FL=gb:D79995.1 gb:NM_014640.1 NM_014640 tubulin tyrosine ligase-like family, member 4 TTLL4 9654 NM_014640 /// XM_005246977 /// XM_005246978 /// XM_006712873 /// XM_006712874 /// XM_006712875 /// XM_006712876 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016874 // ligase activity // inferred from electronic annotation 203704_s_at AW118862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW118862 /FEA=EST /DB_XREF=gi:6087446 /DB_XREF=est:xd97e12.x1 /CLONE=IMAGE:2605582 /UG=Hs.171942 ras responsive element binding protein 1 /FL=gb:U26914.1 gb:D49835.1 gb:NM_002955.1 AW118862 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203705_s_at AI333651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI333651 /FEA=EST /DB_XREF=gi:4070210 /DB_XREF=est:qq08e12.x1 /CLONE=IMAGE:1931950 /UG=Hs.173859 frizzled (Drosophila) homolog 7 /FL=gb:AB010881.1 gb:AB017365.1 gb:NM_003507.1 AI333651 frizzled class receptor 7 FZD7 8324 NM_003507 0001944 // vasculature development // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042666 // negative regulation of ectodermal cell fate specification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 203706_s_at NM_003507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003507.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 7 (FZD7), mRNA. /FEA=mRNA /GEN=FZD7 /PROD=frizzled 7 /DB_XREF=gi:4503832 /UG=Hs.173859 frizzled (Drosophila) homolog 7 /FL=gb:AB010881.1 gb:AB017365.1 gb:NM_003507.1 NM_003507 frizzled class receptor 7 FZD7 8324 NM_003507 0001944 // vasculature development // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042666 // negative regulation of ectodermal cell fate specification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 203707_at NM_005741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005741.1 /DEF=Homo sapiens zinc finger protein 263 (ZNF263), mRNA. /FEA=mRNA /GEN=ZNF263 /PROD=zinc finger protein 263 /DB_XREF=gi:5032240 /UG=Hs.182528 zinc finger protein 263 /FL=gb:D88827.1 gb:NM_005741.1 NM_005741 long intergenic non-protein coding RNA 921 /// zinc finger protein 263 LINC00921 /// ZNF263 10127 /// 283876 NM_005741 /// NR_033904 /// XM_005255031 /// XM_006720831 /// XM_006720832 /// XM_006720833 /// XM_006720834 /// XM_006720835 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203708_at NM_002600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002600.1 /DEF=Homo sapiens phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4) (PDE4B), mRNA. /FEA=mRNA /GEN=PDE4B /PROD=phosphodiesterase 4B, cAMP-specific (dunce(Drosophila)-homolog phosphodiesterase E4) /DB_XREF=gi:4505662 /UG=Hs.188 phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4) /FL=gb:M97515.1 gb:L20971.1 gb:NM_002600.1 NM_002600 phosphodiesterase 4B, cAMP-specific PDE4B 5142 NM_001037339 /// NM_001037340 /// NM_001037341 /// NM_001297440 /// NM_001297441 /// NM_001297442 /// NM_002600 /// XM_005270923 /// XM_005270924 /// XM_005270925 /// XM_005270926 /// XM_006710680 0001780 // neutrophil homeostasis // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203709_at NM_000294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000294.1 /DEF=Homo sapiens phosphorylase kinase, gamma 2 (testis) (PHKG2), mRNA. /FEA=mRNA /GEN=PHKG2 /PROD=phosphorylase kinase, gamma 2 (testis) /DB_XREF=gi:4505784 /UG=Hs.196177 phosphorylase kinase, gamma 2 (testis) /FL=gb:BC002541.1 gb:M31606.1 gb:NM_000294.1 NM_000294 phosphorylase kinase, gamma 2 (testis) PHKG2 5261 NM_000294 /// NM_001172432 /// XM_005255363 /// XM_005255364 /// XM_005255365 /// XM_006721054 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045819 // positive regulation of glycogen catabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005964 // phosphorylase kinase complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004689 // phosphorylase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // traceable author statement 203710_at NM_002222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002222.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 1 (ITPR1), mRNA. /FEA=mRNA /GEN=ITPR1 /PROD=inositol 1,4,5-triphosphate receptor, type 1 /DB_XREF=gi:10835022 /UG=Hs.198443 inositol 1,4,5-triphosphate receptor, type 1 /FL=gb:NM_002222.1 gb:D26070.1 NM_002222 inositol 1,4,5-trisphosphate receptor, type 1 ITPR1 3708 NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity 203711_s_at NM_014362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014362.1 /DEF=Homo sapiens 3-hydroxyisobutyryl-Coenzyme A hydrolase (HIBCH), mRNA. /FEA=mRNA /GEN=HIBCH /PROD=3-hydroxyisobutyryl-Coenzyme A hydrolase /DB_XREF=gi:7657159 /UG=Hs.236642 3-hydroxyisobutyryl-Coenzyme A hydrolase /FL=gb:BC005190.1 gb:U66669.1 gb:NM_014362.1 NM_014362 3-hydroxyisobutyryl-CoA hydrolase HIBCH 26275 NM_014362 /// NM_198047 0006574 // valine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003860 // 3-hydroxyisobutyryl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 203712_at NM_014878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014878.1 /DEF=Homo sapiens KIAA0020 gene product (KIAA0020), mRNA. /FEA=mRNA /GEN=KIAA0020 /PROD=KIAA0020 gene product /DB_XREF=gi:7661865 /UG=Hs.2471 KIAA0020 gene product /FL=gb:D13645.1 gb:NM_014878.1 NM_014878 KIAA0020 KIAA0020 9933 NM_001031691 /// NM_014878 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203713_s_at NM_004524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004524.1 /DEF=Homo sapiens lethal giant larvae (Drosophila) homolog 2 (LLGL2), mRNA. /FEA=mRNA /GEN=LLGL2 /PROD=lethal giant larvae (Drosophila) homolog 2 /DB_XREF=gi:4758679 /UG=Hs.3123 lethal giant larvae (Drosophila) homolog 2 /FL=gb:NM_004524.1 NM_004524 lethal giant larvae homolog 2 (Drosophila) LLGL2 3993 NM_001015002 /// NM_001031803 /// NM_004524 /// XM_006721897 /// XM_006721898 /// XM_006721899 /// XR_243659 0006887 // exocytosis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 203714_s_at NM_003193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003193.2 /DEF=Homo sapiens tubulin-specific chaperone e (TBCE), mRNA. /FEA=mRNA /GEN=TBCE /PROD=beta-tubulin cofactor E /DB_XREF=gi:6006029 /UG=Hs.32675 tubulin-specific chaperone e /FL=gb:U61232.1 gb:NM_003193.2 NM_003193 tubulin folding cofactor E TBCE 6905 NM_001079515 /// NM_001287801 /// NM_001287802 /// NM_003193 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014889 // muscle atrophy // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203715_at NM_003193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003193.2 /DEF=Homo sapiens tubulin-specific chaperone e (TBCE), mRNA. /FEA=mRNA /GEN=TBCE /PROD=beta-tubulin cofactor E /DB_XREF=gi:6006029 /UG=Hs.32675 tubulin-specific chaperone e /FL=gb:U61232.1 gb:NM_003193.2 NM_003193 tubulin folding cofactor E TBCE 6905 NM_001079515 /// NM_001287801 /// NM_001287802 /// NM_003193 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014889 // muscle atrophy // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203716_s_at M80536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80536.1 /DEF=H.sapiens dipeptidyl peptidase IV (DPP4) mRNA, complete cds. /FEA=mRNA /GEN=DPP4 /PROD=dipeptidyl peptidase IV /DB_XREF=gi:181569 /UG=Hs.44926 dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) /FL=gb:M80536.1 gb:NM_001935.1 M80536 dipeptidyl-peptidase 4 DPP4 1803 NM_001935 /// XM_005246371 0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203717_at NM_001935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001935.1 /DEF=Homo sapiens dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) (DPP4), mRNA. /FEA=mRNA /GEN=DPP4 /PROD=dipeptidylpeptidase IV (CD26, adenosinedeaminase complexing protein 2) /DB_XREF=gi:4503366 /UG=Hs.44926 dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) /FL=gb:M80536.1 gb:NM_001935.1 NM_001935 dipeptidyl-peptidase 4 DPP4 1803 NM_001935 /// XM_005246371 0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203718_at NM_006702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006702.1 /DEF=Homo sapiens neuropathy target esterase (NTE), mRNA. /FEA=mRNA /GEN=NTE /PROD=neuropathy target esterase /DB_XREF=gi:5729950 /UG=Hs.5038 neuropathy target esterase /FL=gb:NM_006702.1 NM_006702 patatin-like phospholipase domain containing 6 PNPLA6 10908 NM_001166111 /// NM_001166112 /// NM_001166113 /// NM_001166114 /// NM_006702 0001525 // angiogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004622 // lysophospholipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203719_at NM_001983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001983.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), mRNA. /FEA=mRNA /GEN=ERCC1 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 1 (includesoverlapping antisense sequence) /DB_XREF=gi:4503598 /UG=Hs.59544 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) /FL=gb:M28650.1 gb:AF001925.1 gb:NM_001983.1 gb:M13194.1 NM_001983 excision repair cross-complementation group 1 ERCC1 2067 NM_001166049 /// NM_001983 /// NM_202001 /// XM_005258634 /// XM_005258635 /// XM_005258636 /// XM_005258637 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001302 // replicative cell aging // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from genetic interaction /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from genetic interaction /// 0006312 // mitotic recombination // inferred from mutant phenotype /// 0006949 // syncytium formation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0009650 // UV protection // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0001094 // TFIID-class transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043566 // structure-specific DNA binding // inferred from direct assay 203720_s_at NM_001983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001983.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), mRNA. /FEA=mRNA /GEN=ERCC1 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 1 (includesoverlapping antisense sequence) /DB_XREF=gi:4503598 /UG=Hs.59544 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) /FL=gb:M28650.1 gb:AF001925.1 gb:NM_001983.1 gb:M13194.1 NM_001983 excision repair cross-complementation group 1 ERCC1 2067 NM_001166049 /// NM_001983 /// NM_202001 /// XM_005258634 /// XM_005258635 /// XM_005258636 /// XM_005258637 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001302 // replicative cell aging // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from genetic interaction /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from genetic interaction /// 0006312 // mitotic recombination // inferred from mutant phenotype /// 0006949 // syncytium formation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0009650 // UV protection // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0001094 // TFIID-class transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043566 // structure-specific DNA binding // inferred from direct assay 203721_s_at NM_016001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016001.1 /DEF=Homo sapiens CGI-48 protein (LOC51096), mRNA. /FEA=mRNA /GEN=LOC51096 /PROD=CGI-48 protein /DB_XREF=gi:7705764 /UG=Hs.6153 CGI-48 protein /FL=gb:AF151806.1 gb:NM_016001.1 NM_016001 UTP18 small subunit (SSU) processome component homolog (yeast) UTP18 51096 NM_016001 /// XM_006721930 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203722_at NM_003748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003748.1 /DEF=Homo sapiens aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase; pyrroline-5-carboxylate dehydrogenase) (ALDH4), mRNA. /FEA=mRNA /GEN=ALDH4 /PROD=aldehyde dehydrogenase 4 (glutamategamma-semialdehyde dehydrogenase; pyrroline-5-carboxylatedehydrogenase) /DB_XREF=gi:4502036 /UG=Hs.77448 aldehyde dehydrogenase 4 family, member A1 /FL=gb:U24266.1 gb:NM_003748.1 NM_003748 aldehyde dehydrogenase 4 family, member A1 ALDH4A1 8659 NM_001161504 /// NM_003748 /// NM_170726 0006560 // proline metabolic process // traceable author statement /// 0006561 // proline biosynthetic process // inferred from electronic annotation /// 0006562 // proline catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003842 // 1-pyrroline-5-carboxylate dehydrogenase activity // not recorded /// 0004029 // aldehyde dehydrogenase (NAD) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203723_at NM_002221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002221.1 /DEF=Homo sapiens inositol 1,4,5-trisphosphate 3-kinase B (ITPKB), mRNA. /FEA=mRNA /GEN=ITPKB /PROD=1D-myo-inositol-trisphosphate 3-kinase B /DB_XREF=gi:4504790 /UG=Hs.78877 inositol 1,4,5-trisphosphate 3-kinase B /FL=gb:NM_002221.1 NM_002221 inositol-trisphosphate 3-kinase B ITPKB 3707 NM_002221 /// XM_005273120 0000165 // MAPK cascade // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203724_s_at NM_014961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014961.1 /DEF=Homo sapiens KIAA0871 protein (KIAA0871), mRNA. /FEA=mRNA /GEN=KIAA0871 /PROD=KIAA0871 protein /DB_XREF=gi:7662351 /UG=Hs.7972 KIAA0871 protein /FL=gb:AB020678.1 gb:NM_014961.1 NM_014961 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 203725_at NM_001924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001924.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), mRNA. /FEA=mRNA /GEN=GADD45A /PROD=growth arrest and DNA-damage-inducible, alpha /DB_XREF=gi:9790904 /UG=Hs.80409 growth arrest and DNA-damage-inducible, alpha /FL=gb:M60974.1 gb:NM_001924.2 NM_001924 growth arrest and DNA-damage-inducible, alpha GADD45A 1647 NM_001199741 /// NM_001199742 /// NM_001924 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007098 // centrosome cycle // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001047 // core promoter binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203726_s_at NM_000227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000227.1 /DEF=Homo sapiens laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) (LAMA3), mRNA. /FEA=mRNA /GEN=LAMA3 /PROD=laminin alpha 3 subunit precursor /DB_XREF=gi:4557710 /UG=Hs.83450 laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) /FL=gb:NM_000227.1 gb:L34155.1 NM_000227 laminin, alpha 3 LAMA3 3909 NM_000227 /// NM_001127717 /// NM_001127718 /// NM_198129 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203727_at NM_006929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006929.2 /DEF=Homo sapiens superkiller viralicidic activity 2 (S. cerevisiae homolog)-like (SKIV2L), mRNA. /FEA=mRNA /GEN=SKIV2L /PROD=superkiller viralicidic activity 2 (S.cerevisiae homolog)-like /DB_XREF=gi:13787218 /UG=Hs.89864 superkiller viralicidic activity 2 (S. cerevisiae homolog)-like /FL=gb:NM_006929.2 gb:U09877.1 NM_006929 superkiller viralicidic activity 2-like (S. cerevisiae) SKIV2L 6499 NM_006929 /// XM_006715168 /// XM_006725497 /// XR_430936 /// XR_430997 /// XR_431014 /// XR_431044 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0055087 // Ski complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation 203728_at NM_001188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001188.1 /DEF=Homo sapiens BCL2-antagonistkiller 1 (BAK1), mRNA. /FEA=mRNA /GEN=BAK1 /PROD=BCL2-antagonistkiller 1 /DB_XREF=gi:4502362 /UG=Hs.93213 BCL2-antagonistkiller 1 /FL=gb:BC004431.1 gb:NM_001188.1 gb:U16811.1 gb:U23765.1 NM_001188 BCL2-antagonist/killer 1 BAK1 578 NM_001188 /// XR_241910 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred from genetic interaction /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0002352 // B cell negative selection // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0010046 // response to mycotoxin // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0010248 // establishment or maintenance of transmembrane electrochemical gradient // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034644 // cellular response to UV // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0044346 // fibroblast apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060068 // vagina development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051400 // BH domain binding // inferred from electronic annotation 203729_at NM_001425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001425.1 /DEF=Homo sapiens epithelial membrane protein 3 (EMP3), mRNA. /FEA=mRNA /GEN=EMP3 /PROD=epithelial membrane protein 3 /DB_XREF=gi:4503562 /UG=Hs.9999 epithelial membrane protein 3 /FL=gb:U52101.1 gb:U87947.1 gb:NM_001425.1 NM_001425 epithelial membrane protein 3 EMP3 2014 NM_001425 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203730_s_at BF196931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196931 /FEA=EST /DB_XREF=gi:11085491 /DB_XREF=est:7l80d06.x1 /CLONE=IMAGE:3527842 /UG=Hs.110839 zinc finger protein homologous to Zfp95 in mouse /FL=gb:NM_014569.1 gb:AB023232.1 BF196931 zinc finger with KRAB and SCAN domains 5 ZKSCAN5 23660 NM_014569 /// NM_145102 /// XM_005250242 /// XM_005250243 /// XM_006715912 /// XM_006715913 /// XM_006715914 /// XM_006715915 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203731_s_at NM_014569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014569.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp95 in mouse (ZFP95), mRNA. /FEA=mRNA /GEN=ZFP95 /PROD=zinc finger protein homologous to Zfp95 inmouse /DB_XREF=gi:11036641 /UG=Hs.110839 zinc finger protein homologous to Zfp95 in mouse /FL=gb:NM_014569.1 gb:AB023232.1 NM_014569 zinc finger with KRAB and SCAN domains 5 ZKSCAN5 23660 NM_014569 /// NM_145102 /// XM_005250242 /// XM_005250243 /// XM_006715912 /// XM_006715913 /// XM_006715914 /// XM_006715915 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203732_at NM_016213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016213.1 /DEF=Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), mRNA. /FEA=mRNA /GEN=TRIP4 /PROD=activating signal cointegrator 1 /DB_XREF=gi:7706430 /UG=Hs.116784 thyroid hormone receptor interactor 4 /FL=gb:AF168418.1 gb:NM_016213.1 NM_016213 thyroid hormone receptor interactor 4 TRIP4 9325 NM_016213 /// XM_005254789 /// XR_243130 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203733_at NM_014015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014015.2 /DEF=Homo sapiens MYLE protein (MYLE), mRNA. /FEA=mRNA /GEN=MYLE /PROD=MYLE protein /DB_XREF=gi:13384596 /UG=Hs.11902 MYLE protein /FL=gb:BC001083.1 gb:AF108145.2 gb:NM_014015.2 NM_014015 Dexi homolog (mouse) DEXI 28955 NM_014015 203734_at NM_018416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018416.1 /DEF=Homo sapiens FOXJ2 forkhead factor (LOC55810), mRNA. /FEA=mRNA /GEN=LOC55810 /PROD=FOXJ2 forkhead factor /DB_XREF=gi:8923841 /UG=Hs.120844 FOXJ2 forkhead factor /FL=gb:AF155132.1 gb:NM_018416.1 NM_018416 forkhead box J2 FOXJ2 55810 NM_018416 /// XM_005253430 /// XM_005253431 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from direct assay 203735_x_at N35896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N35896 /FEA=EST /DB_XREF=gi:1157038 /DB_XREF=est:yy28c08.s1 /CLONE=IMAGE:272558 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) /FL=gb:AF034802.1 gb:NM_003622.1 N35896 PTPRF interacting protein, binding protein 1 (liprin beta 1) PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0007155 // cell adhesion // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 203736_s_at NM_003622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003622.1 /DEF=Homo sapiens PTPRF interacting protein, binding protein 1 (liprin beta 1) (PPFIBP1), mRNA. /FEA=mRNA /GEN=PPFIBP1 /PROD=PTPRF interacting protein, binding protein 1(liprin beta 1) /DB_XREF=gi:4505986 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) /FL=gb:AF034802.1 gb:NM_003622.1 NM_003622 PTPRF interacting protein, binding protein 1 (liprin beta 1) PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0007155 // cell adhesion // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 203737_s_at NM_015062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015062.1 /DEF=Homo sapiens KIAA0595 protein (KIAA0595), mRNA. /FEA=mRNA /GEN=KIAA0595 /PROD=KIAA0595 protein /DB_XREF=gi:13124753 /UG=Hs.146957 KIAA0595 protein /FL=gb:BC002561.1 gb:AF325193.1 gb:NM_015062.1 NM_015062 peroxisome proliferator-activated receptor gamma, coactivator-related 1 PPRC1 23082 NM_001288727 /// NM_001288728 /// NM_015062 /// XM_005269656 /// XM_005269658 /// XM_006717730 /// XM_006717731 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203738_at AI421192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI421192 /FEA=EST /DB_XREF=gi:4267123 /DB_XREF=est:tf24e12.x1 /CLONE=IMAGE:2097166 /UG=Hs.151046 hypothetical protein FLJ11193 /FL=gb:NM_018356.1 AI421192 chromosome 5 open reading frame 22 C5orf22 55322 NM_018356 /// XM_005248319 /// XM_006714479 /// XM_006714480 /// XR_241704 0008013 // beta-catenin binding // inferred from electronic annotation 203739_at NM_006526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006526.1 /DEF=Homo sapiens zinc finger protein 217 (ZNF217), mRNA. /FEA=mRNA /GEN=ZNF217 /PROD=zinc finger protein 217 /DB_XREF=gi:5730123 /UG=Hs.155040 zinc finger protein 217 /FL=gb:AF041259.1 gb:NM_006526.1 NM_006526 zinc finger protein 217 ZNF217 7764 NM_006526 /// XM_005260545 /// XM_006723875 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203740_at NM_005792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005792.1 /DEF=Homo sapiens M-phase phosphoprotein 6 (MPHOSPH6), mRNA. /FEA=mRNA /GEN=MPHOSPH6 /PROD=M-phase phosphoprotein 6 /DB_XREF=gi:5031918 /UG=Hs.152720 M-phase phosphoprotein 6 /FL=gb:BC005242.1 gb:NM_005792.1 NM_005792 M-phase phosphoprotein 6 MPHOSPH6 10200 NM_005792 0000087 // mitotic M phase // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation 0000176 // nuclear exosome (RNase complex) // traceable author statement /// 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203741_s_at NM_001114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001114.1 /DEF=Homo sapiens adenylate cyclase 7 (ADCY7), mRNA. /FEA=mRNA /GEN=ADCY7 /PROD=adenylate cyclase 7 /DB_XREF=gi:4557254 /UG=Hs.172199 adenylate cyclase 7 /FL=gb:D25538.1 gb:NM_001114.1 NM_001114 adenylate cyclase 7 ADCY7 113 NM_001114 /// NM_001286057 /// XM_005255779 /// XM_005255780 /// XM_005255781 /// XM_005255782 /// XM_005255783 /// XM_005255784 /// XM_005255785 /// XM_005255786 /// XM_006721128 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from direct assay /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 203742_s_at BF674842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF674842 /FEA=EST /DB_XREF=gi:11948737 /DB_XREF=est:602136708F1 /CLONE=IMAGE:4273393 /UG=Hs.173824 thymine-DNA glycosylase /FL=gb:U51166.1 gb:NM_003211.1 BF674842 G/T mismatch-specific thymine DNA glycosylase-like /// thymine-DNA glycosylase LOC732360 /// TDG 6996 /// 732360 NM_001008411 /// NM_003211 /// XM_005269125 /// XR_133016 /// XR_429113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from sequence or structural similarity /// 0045008 // depyrimidination // traceable author statement /// 0080111 // DNA demethylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032183 // SUMO binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from sequence or structural similarity 203743_s_at NM_003211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003211.1 /DEF=Homo sapiens thymine-DNA glycosylase (TDG), mRNA. /FEA=mRNA /GEN=TDG /PROD=thymine-DNA glycosylase /DB_XREF=gi:4507422 /UG=Hs.173824 thymine-DNA glycosylase /FL=gb:U51166.1 gb:NM_003211.1 NM_003211 thymine-DNA glycosylase TDG 6996 NM_001008411 /// NM_003211 /// XM_005269125 /// XR_429113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from sequence or structural similarity /// 0045008 // depyrimidination // traceable author statement /// 0080111 // DNA demethylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032183 // SUMO binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from sequence or structural similarity 203744_at NM_005342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005342.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 4 (HMG4), mRNA. /FEA=mRNA /GEN=HMG4 /PROD=high-mobility group (nonhistone chromosomal)protein 4 /DB_XREF=gi:4885420 /UG=Hs.19114 high-mobility group (nonhistone chromosomal) protein 4 /FL=gb:NM_005342.1 NM_005342 high mobility group box 3 HMGB3 3149 NM_005342 /// XM_005274665 /// XM_005274666 /// XM_005274667 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 203745_at AI801013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI801013 /FEA=EST /DB_XREF=gi:5366485 /DB_XREF=est:wg15d09.x1 /CLONE=IMAGE:2365169 /UG=Hs.211571 holocytochrome c synthase (cytochrome c heme-lyase) /FL=gb:U36787.1 gb:NM_005333.1 AI801013 holocytochrome c synthase HCCS 3052 NM_001122608 /// NM_001171991 /// NM_005333 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004408 // holocytochrome-c synthase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203746_s_at NM_005333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005333.1 /DEF=Homo sapiens holocytochrome c synthase (cytochrome c heme-lyase) (HCCS), mRNA. /FEA=mRNA /GEN=HCCS /PROD=holocytochrome c synthase (cytochrome cheme-lyase) /DB_XREF=gi:4885400 /UG=Hs.211571 holocytochrome c synthase (cytochrome c heme-lyase) /FL=gb:U36787.1 gb:NM_005333.1 NM_005333 holocytochrome c synthase HCCS 3052 NM_001122608 /// NM_001171991 /// NM_005333 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004408 // holocytochrome-c synthase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203747_at NM_004925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004925.2 /DEF=Homo sapiens aquaporin 3 (AQP3), mRNA. /FEA=mRNA /GEN=AQP3 /PROD=aquaporin 3 /DB_XREF=gi:9257193 /UG=Hs.234642 aquaporin 3 /FL=gb:NM_004925.2 NM_004925 aquaporin 3 (Gill blood group) AQP3 360 NM_004925 0002684 // positive regulation of immune system process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015793 // glycerol transport // inferred from electronic annotation /// 0015840 // urea transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0033280 // response to vitamin D // traceable author statement /// 0042476 // odontogenesis // inferred from expression pattern /// 0045616 // regulation of keratinocyte differentiation // traceable author statement /// 0051592 // response to calcium ion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // traceable author statement /// 0015254 // glycerol channel activity // inferred from direct assay 203748_x_at NM_016839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016839.1 /DEF=Homo sapiens RNA binding motif, single stranded interacting protein 1 (RBMS1), transcript variant MSSP-2, mRNA. /FEA=mRNA /GEN=RBMS1 /PROD=RNA binding motif, single stranded interactingprotein 1, isoform b /DB_XREF=gi:8400723 /UG=Hs.241567 RNA binding motif, single stranded interacting protein 1 /FL=gb:NM_016839.1 NM_016839 RNA binding motif, single stranded interacting protein 1 RBMS1 5937 NM_002897 /// NM_016836 /// NM_016839 /// XM_005246737 /// XM_005246738 /// XM_005246739 /// XM_005246740 /// XM_005246741 /// XM_006712671 /// XM_006712672 /// XM_006712673 /// XM_006712674 /// XM_006712675 0006260 // DNA replication // non-traceable author statement /// 0006396 // RNA processing // traceable author statement 0005634 // nucleus // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203749_s_at AI806984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806984 /FEA=EST /DB_XREF=gi:5393550 /DB_XREF=est:wf24g08.x1 /CLONE=IMAGE:2356574 /UG=Hs.250505 retinoic acid receptor, alpha /FL=gb:NM_000964.1 AI806984 retinoic acid receptor, alpha RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay 203750_s_at NM_000964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000964.1 /DEF=Homo sapiens retinoic acid receptor, alpha (RARA), mRNA. /FEA=mRNA /GEN=RARA /PROD=retinoic acid receptor, alpha /DB_XREF=gi:4506418 /UG=Hs.250505 retinoic acid receptor, alpha /FL=gb:NM_000964.1 NM_000964 retinoic acid receptor, alpha RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay 203751_x_at AI762296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762296 /FEA=EST /DB_XREF=gi:5177963 /DB_XREF=est:wh86e06.x1 /CLONE=IMAGE:2387650 /UG=Hs.2780 jun D proto-oncogene /FL=gb:NM_005354.2 AI762296 jun D proto-oncogene JUND 3727 NM_001286968 /// NM_005354 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203752_s_at NM_005354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005354.2 /DEF=Homo sapiens jun D proto-oncogene (JUND), mRNA. /FEA=mRNA /GEN=JUND /PROD=jun D proto-oncogene /DB_XREF=gi:10938013 /UG=Hs.2780 jun D proto-oncogene /FL=gb:NM_005354.2 NM_005354 jun D proto-oncogene JUND 3727 NM_001286968 /// NM_005354 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203753_at NM_003199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003199.1 /DEF=Homo sapiens transcription factor 4 (TCF4), mRNA. /FEA=mRNA /GEN=TCF4 /PROD=transcription factor 4, isoform b /DB_XREF=gi:4507398 /UG=Hs.326198 transcription factor 4 /FL=gb:M74719.1 gb:NM_003199.1 NM_003199 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 203754_s_at NM_001519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001519.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 (TAF3B2), mRNA. /FEA=mRNA /GEN=TAF3B2 /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase III, GTF3B subunit 2 /DB_XREF=gi:4507354 /UG=Hs.32935 TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 /FL=gb:U75276.1 gb:NM_001519.1 gb:U28838.1 NM_001519 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit BRF1 2972 NM_001242786 /// NM_001242787 /// NM_001242788 /// NM_001242789 /// NM_001242790 /// NM_001519 /// NM_145685 /// NM_145696 /// XM_005267561 /// XM_005267563 /// XM_006720122 /// XM_006720123 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000126 // transcription factor TFIIIB complex // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203755_at NM_001211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001211.2 /DEF=Homo sapiens budding uninhibited by benzimidazoles 1 (yeast homolog), beta (BUB1B), mRNA. /FEA=mRNA /GEN=BUB1B /PROD=budding uninhibited by benzimidazoles 1 (yeasthomolog), beta /DB_XREF=gi:5729749 /UG=Hs.36708 budding uninhibited by benzimidazoles 1 (yeast homolog), beta /FL=gb:AF053306.1 gb:AF035933.1 gb:AF068760.1 gb:AF046918.1 gb:AF107297.1 gb:AF046079.2 gb:NM_001211.2 NM_001211 BUB1 mitotic checkpoint serine/threonine kinase B BUB1B 701 NM_001211 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from physical interaction /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0071459 // protein localization to chromosome, centromeric region // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // non-traceable author statement /// 0000776 // kinetochore // traceable author statement /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000778 // condensed nuclear chromosome kinetochore // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005680 // anaphase-promoting complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203756_at NM_014786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014786.1 /DEF=Homo sapiens KIAA0337 gene product (KIAA0337), mRNA. /FEA=mRNA /GEN=KIAA0337 /PROD=KIAA0337 gene product /DB_XREF=gi:7662063 /UG=Hs.45180 KIAA0337 gene product /FL=gb:AB002335.1 gb:NM_014786.1 NM_014786 Rho guanine nucleotide exchange factor (GEF) 17 ARHGEF17 9828 NM_014786 /// XM_006718752 0007155 // cell adhesion // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203757_s_at BC005008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005008.1 /DEF=Homo sapiens, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen), clone MGC:10467, mRNA, complete cds. /FEA=mRNA /PROD=carcinoembryonic antigen-related cell adhesionmolecule 6 (non-specific cross reacting antigen) /DB_XREF=gi:13477106 /UG=Hs.73848 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) /FL=gb:BC005008.1 gb:M18216.1 gb:M29541.1 gb:NM_002483.1 BC005008 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) CEACAM6 4680 NM_002483 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203758_at AV729484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV729484 /FEA=EST /DB_XREF=gi:10838905 /DB_XREF=est:AV729484 /CLONE=HTCAVA12 /UG=Hs.75262 cathepsin O /FL=gb:NM_001334.1 AV729484 cathepsin O CTSO 1519 NM_001334 0006508 // proteolysis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203759_at NM_006278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006278.1 /DEF=Homo sapiens sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) (SIAT4C), mRNA. /FEA=mRNA /GEN=SIAT4C /PROD=sialyltransferase 4C (beta-galactosidasealpha-2,3-sialytransferase) /DB_XREF=gi:5454057 /UG=Hs.75268 sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) /FL=gb:L23767.1 gb:NM_006278.1 NM_006278 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST3GAL4 6484 NM_001254757 /// NM_001254758 /// NM_001254759 /// NM_006278 /// XM_005271649 /// XM_005271650 /// XM_005271651 /// XM_006718896 /// XM_006718897 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047288 // monosialoganglioside sialyltransferase activity // inferred from electronic annotation 203760_s_at U44403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U44403.1 /DEF=Human Src-like adapter protein mRNA, complete cds. /FEA=mRNA /PROD=Src-like adapter protein /DB_XREF=gi:1809245 /UG=Hs.75367 Src-like-adapter /FL=gb:U30473.1 gb:D89077.1 gb:U44403.1 gb:NM_006748.1 U44403 Src-like-adaptor SLA 6503 NM_001045556 /// NM_001045557 /// NM_001282964 /// NM_001282965 /// NM_006748 0009967 // positive regulation of signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203761_at NM_006748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006748.1 /DEF=Homo sapiens Src-like-adapter (SLA), mRNA. /FEA=mRNA /GEN=SLA /PROD=Src-like-adapter /DB_XREF=gi:5803170 /UG=Hs.75367 Src-like-adapter /FL=gb:U30473.1 gb:D89077.1 gb:U44403.1 gb:NM_006748.1 NM_006748 Src-like-adaptor SLA 6503 NM_001045556 /// NM_001045557 /// NM_001282964 /// NM_001282965 /// NM_006748 0009967 // positive regulation of signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203762_s_at NM_016008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016008.1 /DEF=Homo sapiens CGI-60 protein (LOC51626), mRNA. /FEA=mRNA /GEN=LOC51626 /PROD=CGI-60 protein /DB_XREF=gi:7706299 /UG=Hs.7627 CGI-60 protein /FL=gb:AF151818.1 gb:NM_016008.1 NM_016008 dynein, cytoplasmic 2, light intermediate chain 1 DYNC2LI1 51626 NM_001012665 /// NM_001193464 /// NM_015522 /// NM_016008 /// XM_005264364 /// XM_005264365 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0030286 // dynein complex // inferred from electronic annotation /// 0030990 // intraciliary transport particle // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203763_at NM_016008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016008.1 /DEF=Homo sapiens CGI-60 protein (LOC51626), mRNA. /FEA=mRNA /GEN=LOC51626 /PROD=CGI-60 protein /DB_XREF=gi:7706299 /UG=Hs.7627 CGI-60 protein /FL=gb:AF151818.1 gb:NM_016008.1 NM_016008 dynein, cytoplasmic 2, light intermediate chain 1 DYNC2LI1 51626 NM_001012665 /// NM_001193464 /// NM_015522 /// NM_016008 /// XM_005264364 /// XM_005264365 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0030286 // dynein complex // inferred from electronic annotation /// 0030990 // intraciliary transport particle // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203764_at NM_014750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014750.1 /DEF=Homo sapiens KIAA0008 gene product (KIAA0008), mRNA. /FEA=mRNA /GEN=KIAA0008 /PROD=KIAA0008 gene product /DB_XREF=gi:7661851 /UG=Hs.77695 KIAA0008 gene product /FL=gb:D13633.1 gb:NM_014750.1 NM_014750 discs, large (Drosophila) homolog-associated protein 5 DLGAP5 9787 NM_001146015 /// NM_014750 0000087 // mitotic M phase // inferred from direct assay /// 0000087 // mitotic M phase // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 203765_at NM_012198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012198.1 /DEF=Homo sapiens grancalcin (GCL), mRNA. /FEA=mRNA /GEN=GCL /PROD=grancalcin /DB_XREF=gi:6912387 /UG=Hs.79381 grancalcin /FL=gb:BC005214.1 gb:M81637.1 gb:NM_012198.1 NM_012198 grancalcin, EF-hand calcium binding protein GCA 25801 NM_012198 /// XM_005246446 /// XM_006712398 /// XM_006712399 /// XM_006712400 /// XM_006712401 0006508 // proteolysis // not recorded /// 0061025 // membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203766_s_at NM_012134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012134.1 /DEF=Homo sapiens leiomodin 1 (smooth muscle) (LMOD1), mRNA. /FEA=mRNA /GEN=LMOD1 /PROD=leiomodin 1 (smooth muscle) /DB_XREF=gi:6912323 /UG=Hs.79386 leiomodin 1 (smooth muscle) /FL=gb:NM_012134.1 NM_012134 leiomodin 1 (smooth muscle) LMOD1 25802 NM_012134 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203767_s_at AI122754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI122754 /FEA=EST /DB_XREF=gi:3538520 /DB_XREF=est:qa48e01.x1 /CLONE=IMAGE:1690008 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1 AI122754 steroid sulfatase (microsomal), isozyme S STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203768_s_at AU138166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU138166 /FEA=EST /DB_XREF=gi:10999687 /DB_XREF=est:AU138166 /CLONE=PLACE1007987 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1 AU138166 steroid sulfatase (microsomal), isozyme S STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203769_s_at NM_000351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000351.2 /DEF=Homo sapiens steroid sulfatase (microsomal), arylsulfatase C, isozyme S (STS), mRNA. /FEA=mRNA /GEN=STS /PROD=steroid sulfatase (microsomal), arylsulfatase C,isozyme S /DB_XREF=gi:13162281 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1 NM_000351 steroid sulfatase (microsomal), isozyme S STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203770_s_at J04964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04964.1 /DEF=Human steroid sulfatase (microsomal), complete cds. /FEA=mRNA /GEN=STS /DB_XREF=gi:338564 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1 J04964 steroid sulfatase (microsomal), isozyme S STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203771_s_at AA740186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA740186 /FEA=EST /DB_XREF=gi:2778778 /DB_XREF=est:ob26e06.s1 /CLONE=IMAGE:1324834 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1 AA740186 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203772_at U34877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U34877.1 /DEF=Homo sapiens biliverdin-IX alpha reductase mRNA, complete cds. /FEA=mRNA /PROD=biliverdin-IX alpha reductase /DB_XREF=gi:1143231 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1 U34877 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203773_x_at NM_000712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000712.1 /DEF=Homo sapiens biliverdin reductase A (BLVRA), mRNA. /FEA=mRNA /GEN=BLVRA /PROD=biliverdin reductase A /DB_XREF=gi:4502416 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1 NM_000712 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203774_at NM_000254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000254.1 /DEF=Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), mRNA. /FEA=mRNA /GEN=MTR /PROD=5-methyltetrahydrofolate-homocysteinemethyltransferase /DB_XREF=gi:4557764 /UG=Hs.82283 5-methyltetrahydrofolate-homocysteine methyltransferase /FL=gb:U73338.1 gb:U75743.1 gb:U71285.1 gb:NM_000254.1 NM_000254 5-methyltetrahydrofolate-homocysteine methyltransferase MTR 4548 NM_000254 /// NM_001291939 /// NM_001291940 /// XM_005273141 /// XM_005273143 /// XM_005273145 /// XM_006711769 /// XM_006711770 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042558 // pteridine-containing compound metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008705 // methionine synthase activity // inferred from electronic annotation /// 0008898 // S-adenosylmethionine-homocysteine S-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203775_at NM_014251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014251.1 /DEF=Homo sapiens solute carrier family 25, member 13 (citrin) (SLC25A13), mRNA. /FEA=mRNA /GEN=SLC25A13 /PROD=solute carrier family 25, member 13 (citrin) /DB_XREF=gi:7657580 /UG=Hs.9599 solute carrier family 25, member 13 (citrin) /FL=gb:AF118838.1 gb:NM_014251.1 NM_014251 solute carrier family 25 (aspartate/glutamate carrier), member 13 SLC25A13 10165 NM_001160210 /// NM_014251 /// NR_027662 /// XM_006715830 /// XM_006715831 /// XM_006715832 /// XM_006715833 /// XM_006715834 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203776_at NM_015698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015698.1 /DEF=Homo sapiens T54 protein (T54), mRNA. /FEA=mRNA /GEN=T54 /PROD=T54 protein /DB_XREF=gi:7662668 /UG=Hs.100391 T54 protein /FL=gb:BC000397.1 gb:BC003148.1 gb:U66359.1 gb:NM_015698.1 NM_015698 G patch domain and KOW motifs GPKOW 27238 NM_015698 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203777_s_at NM_003952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003952.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 70kD, polypeptide 2 (RPS6KB2), mRNA. /FEA=mRNA /GEN=RPS6KB2 /PROD=p70 ribosomal S6 kinase beta /DB_XREF=gi:4506738 /UG=Hs.103081 ribosomal protein S6 kinase, 70kD, polypeptide 2 /FL=gb:BC000094.1 gb:AB016869.1 gb:AB019245.1 gb:AF099739.1 gb:NM_003952.1 gb:AF076931.1 NM_003952 ribosomal protein S6 kinase, 70kDa, polypeptide 2 RPS6KB2 6199 NM_001007071 /// NM_003952 /// XM_005274164 /// XM_005274165 /// XM_006718655 /// XM_006718656 /// XM_006718657 /// XR_247207 /// XR_247208 0006412 // translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 203778_at NM_005908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005908.1 /DEF=Homo sapiens mannosidase, beta A, lysosomal (MANBA), mRNA. /FEA=mRNA /GEN=MANBA /PROD=mannosidase, beta A, lysosomal /DB_XREF=gi:5174522 /UG=Hs.115945 mannosidase, beta A, lysosomal /FL=gb:U60337.1 gb:NM_005908.1 NM_005908 mannosidase, beta A, lysosomal MANBA 4126 NM_005908 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006516 // glycoprotein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0046355 // mannan catabolic process // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004567 // beta-mannosidase activity // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 203779_s_at NM_005797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005797.1 /DEF=Homo sapiens epithelial V-like antigen 1 (EVA1), mRNA. /FEA=mRNA /GEN=EVA1 /PROD=epithelial V-like antigen 1 precursor /DB_XREF=gi:5032246 /UG=Hs.116651 epithelial V-like antigen 1 /FL=gb:AF304447.1 gb:AF030455.1 gb:NM_005797.1 gb:AF275945.1 NM_005797 myelin protein zero-like 2 MPZL2 10205 NM_005797 /// NM_144765 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203780_at AF275945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF275945.1 /DEF=Homo sapiens epithelial V-like antigen 1 (EVA1) mRNA, complete cds. /FEA=mRNA /GEN=EVA1 /PROD=epithelial V-like antigen 1 /DB_XREF=gi:9392652 /UG=Hs.116651 epithelial V-like antigen 1 /FL=gb:AF304447.1 gb:AF030455.1 gb:NM_005797.1 gb:AF275945.1 AF275945 myelin protein zero-like 2 MPZL2 10205 NM_005797 /// NM_144765 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203781_at NM_004891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004891.1 /DEF=Homo sapiens chromosome 2 open reading frame 1 (C2ORF1), mRNA. /FEA=mRNA /GEN=C2ORF1 /PROD=chromosome 2 open reading frame 1 /DB_XREF=gi:4759047 /UG=Hs.14454 chromosome 2 open reading frame 1 /FL=gb:AF047440.1 gb:NM_004891.1 NM_004891 mitochondrial ribosomal protein L33 MRPL33 9553 NM_004891 /// NM_145330 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 203782_s_at NM_005035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005035.1 /DEF=Homo sapiens polymerase (RNA) mitochondrial (DNA directed) (POLRMT), mRNA. /FEA=mRNA /GEN=POLRMT /PROD=polymerase (RNA) mitochondrial (DNA directed) /DB_XREF=gi:4826925 /UG=Hs.153880 polymerase (RNA) mitochondrial (DNA directed) /FL=gb:U75370.1 gb:NM_005035.1 NM_005035 polymerase (RNA) mitochondrial (DNA directed) POLRMT 5442 NM_005035 /// XM_005259580 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203783_x_at BF057617 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057617 /FEA=EST /DB_XREF=gi:10811513 /DB_XREF=est:7k46g11.x1 /CLONE=IMAGE:3478485 /UG=Hs.153880 polymerase (RNA) mitochondrial (DNA directed) /FL=gb:U75370.1 gb:NM_005035.1 BF057617 polymerase (RNA) mitochondrial (DNA directed) POLRMT 5442 NM_005035 /// XM_005259580 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203784_s_at BG477502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG477502 /FEA=EST /DB_XREF=gi:13409781 /DB_XREF=est:602521562F1 /CLONE=IMAGE:4640031 /UG=Hs.155049 hypothetical protein FLJ11282 /FL=gb:NM_018380.1 BG477502 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203785_s_at NM_018380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018380.1 /DEF=Homo sapiens hypothetical protein FLJ11282 (FLJ11282), mRNA. /FEA=mRNA /GEN=FLJ11282 /PROD=hypothetical protein FLJ11282 /DB_XREF=gi:8922975 /UG=Hs.155049 hypothetical protein FLJ11282 /FL=gb:NM_018380.1 NM_018380 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203786_s_at NM_003287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003287.1 /DEF=Homo sapiens tumor protein D52-like 1 (TPD52L1), mRNA. /FEA=mRNA /GEN=TPD52L1 /PROD=tumor protein D52-like 1 /DB_XREF=gi:4507640 /UG=Hs.16611 tumor protein D52-like 1 /FL=gb:U44427.1 gb:NM_003287.1 NM_003287 tumor protein D52-like 1 TPD52L1 7164 NM_001003395 /// NM_001003396 /// NM_001003397 /// NM_001292026 /// NM_003287 /// XM_005267121 /// XM_005267122 /// XM_005267123 /// XM_005267124 /// XM_006715556 /// XM_006715557 /// XM_006715558 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 203787_at NM_012446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012446.1 /DEF=Homo sapiens single-stranded-DNA-binding protein (SSBP2), mRNA. /FEA=mRNA /GEN=SSBP2 /PROD=single-stranded-DNA-binding protein /DB_XREF=gi:7106422 /UG=Hs.169833 single-stranded-DNA-binding protein /FL=gb:AL080076.1 gb:AF161465.1 gb:NM_012446.1 NM_012446 single-stranded DNA binding protein 2 SSBP2 23635 NM_001256732 /// NM_001256733 /// NM_001256734 /// NM_001256735 /// NM_001256736 /// NM_012446 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203788_s_at AI962897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962897 /FEA=EST /DB_XREF=gi:5755610 /DB_XREF=est:wt24e04.x1 /CLONE=IMAGE:2508414 /UG=Hs.171921 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C /FL=gb:AB000220.1 gb:NM_006379.1 AI962897 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C SEMA3C 10512 NM_006379 /// XM_005250113 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 203789_s_at NM_006379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006379.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C), mRNA. /FEA=mRNA /GEN=SEMA3C /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3C /DB_XREF=gi:5454047 /UG=Hs.171921 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C /FL=gb:AB000220.1 gb:NM_006379.1 NM_006379 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C SEMA3C 10512 NM_006379 /// XM_005250113 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 203790_s_at N54448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N54448 /FEA=EST /DB_XREF=gi:1195768 /DB_XREF=est:yv36h05.s1 /CLONE=IMAGE:244857 /UG=Hs.18426 translational inhibitor protein p14.5 /FL=gb:NM_005836.1 N54448 heat-responsive protein 12 HRSP12 10247 NM_005836 0006449 // regulation of translational termination // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203791_at NM_005509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005509.2 /DEF=Homo sapiens Dmx-like 1 (DMXL1), mRNA. /FEA=mRNA /GEN=DMXL1 /PROD=Dmx-like 1 /DB_XREF=gi:9961348 /UG=Hs.181042 Dmx-like 1 /FL=gb:NM_005509.2 NM_005509 Dmx-like 1 DMXL1 1657 NM_001290321 /// NM_001290322 /// NM_005509 /// XM_005271909 /// XM_005271910 /// XM_005271911 /// XM_005271912 /// XM_005271913 /// XM_006714560 0005515 // protein binding // inferred from electronic annotation 203792_x_at BC004858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004858.1 /DEF=Homo sapiens, zinc finger protein 144 (Mel-18), clone MGC:10336, mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 144 (Mel-18) /DB_XREF=gi:13436061 /UG=Hs.184669 zinc finger protein 144 (Mel-18) /FL=gb:BC004858.1 gb:D13969.1 gb:NM_007144.1 BC004858 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203793_x_at NM_007144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007144.1 /DEF=Homo sapiens zinc finger protein 144 (Mel-18) (ZNF144), mRNA. /FEA=mRNA /GEN=ZNF144 /PROD=zinc finger protein 144 (Mel-18) /DB_XREF=gi:6005963 /UG=Hs.184669 zinc finger protein 144 (Mel-18) /FL=gb:BC004858.1 gb:D13969.1 gb:NM_007144.1 NM_007144 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203794_at NM_014826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014826.1 /DEF=Homo sapiens KIAA0451 gene product (KIAA0451), mRNA. /FEA=mRNA /GEN=KIAA0451 /PROD=KIAA0451 gene product /DB_XREF=gi:7662135 /UG=Hs.18586 KIAA0451 gene product /FL=gb:AB007920.1 gb:NM_014826.1 NM_014826 CDC42 binding protein kinase alpha (DMPK-like) CDC42BPA 8476 NM_003607 /// NM_014826 /// XM_005273317 /// XM_005273318 /// XM_005273320 /// XM_005273321 /// XM_005273322 /// XM_005273323 /// XM_005273324 /// XM_006711834 /// XM_006711835 /// XM_006711836 /// XM_006711837 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007097 // nuclear migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203795_s_at NM_020993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020993.1 /DEF=Homo sapiens B-cell CLLlymphoma 7A (BCL7A), mRNA. /FEA=mRNA /GEN=BCL7A /PROD=B-cell CLLlymphoma 7A /DB_XREF=gi:10337612 /UG=Hs.211563 B-cell CLLlymphoma 7A /FL=gb:NM_020993.1 NM_020993 B-cell CLL/lymphoma 7A BCL7A 605 NM_001024808 /// NM_020993 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 203796_s_at AI950380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI950380 /FEA=EST /DB_XREF=gi:5742690 /DB_XREF=est:wp10g03.x1 /CLONE=IMAGE:2464468 /UG=Hs.211563 B-cell CLLlymphoma 7A /FL=gb:NM_020993.1 AI950380 B-cell CLL/lymphoma 7A BCL7A 605 NM_001024808 /// NM_020993 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 203797_at AF039555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF039555.1 /DEF=Homo sapiens visinin-like protein 1 (VSNL1) mRNA, complete cds. /FEA=mRNA /GEN=VSNL1 /PROD=visinin-like protein 1 /DB_XREF=gi:4104813 /UG=Hs.2288 visinin-like 1 /FL=gb:AF039555.1 gb:NM_003385.1 gb:AB001104.1 gb:U14747.1 AF039555 visinin-like 1 VSNL1 7447 NM_003385 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203798_s_at NM_003385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003385.1 /DEF=Homo sapiens visinin-like 1 (VSNL1), mRNA. /FEA=mRNA /GEN=VSNL1 /PROD=visinin-like 1 /DB_XREF=gi:4507904 /UG=Hs.2288 visinin-like 1 /FL=gb:AF039555.1 gb:NM_003385.1 gb:AB001104.1 gb:U14747.1 NM_003385 visinin-like 1 VSNL1 7447 NM_003385 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203799_at NM_014880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014880.1 /DEF=Homo sapiens KIAA0022 gene product (KIAA0022), mRNA. /FEA=mRNA /GEN=KIAA0022 /PROD=KIAA0022 gene product /DB_XREF=gi:7661867 /UG=Hs.2441 KIAA0022 gene product /FL=gb:D14664.1 gb:NM_014880.1 NM_014880 CD302 molecule /// lymphocyte antigen 75 /// LY75-CD302 readthrough CD302 /// LY75 /// LY75-CD302 4065 /// 9936 /// 100526664 NM_001198759 /// NM_001198760 /// NM_001198763 /// NM_001198764 /// NM_002349 /// NM_014880 0006897 // endocytosis // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203800_s_at BG254653 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG254653 /FEA=EST /DB_XREF=gi:12764469 /DB_XREF=est:602368621F1 /CLONE=IMAGE:4476773 /UG=Hs.247324 hypothetical protein LOC63931 /FL=gb:NM_022100.1 BG254653 mitochondrial ribosomal protein S14 MRPS14 63931 NM_022100 /// NR_037606 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203801_at AA013164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA013164 /FEA=EST /DB_XREF=gi:1474190 /DB_XREF=est:ze35e12.s1 /CLONE=IMAGE:361006 /UG=Hs.247324 hypothetical protein LOC63931 /FL=gb:NM_022100.1 AA013164 mitochondrial ribosomal protein S14 MRPS14 63931 NM_022100 /// NR_037606 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203802_x_at NM_018044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018044.1 /DEF=Homo sapiens hypothetical protein FLJ10267 (FLJ10267), mRNA. /FEA=mRNA /GEN=FLJ10267 /PROD=hypothetical protein FLJ10267 /DB_XREF=gi:8922321 /UG=Hs.272820 hypothetical protein FLJ10267 /FL=gb:NM_018044.1 NM_018044 NOP2/Sun domain family, member 5 NSUN5 55695 NM_001168347 /// NM_001168348 /// NM_018044 /// NM_148956 /// XM_005277604 /// XR_242255 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203803_at N45309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N45309 /FEA=EST /DB_XREF=gi:1186475 /DB_XREF=est:yz17b09.s1 /CLONE=IMAGE:283289 /UG=Hs.278627 prenylcysteine lyase /FL=gb:AF181490.1 gb:NM_016297.1 N45309 prenylcysteine oxidase 1 PCYOX1 51449 NM_016297 0006821 // chloride transport // inferred from electronic annotation /// 0030327 // prenylated protein catabolic process // inferred from direct assay /// 0030327 // prenylated protein catabolic process // non-traceable author statement /// 0030328 // prenylcysteine catabolic process // inferred from electronic annotation /// 0030329 // prenylcysteine metabolic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001735 // prenylcysteine oxidase activity // inferred from direct assay /// 0008555 // chloride-transporting ATPase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016670 // oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor // inferred from electronic annotation 203804_s_at NM_006107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006107.1 /DEF=Homo sapiens acid-inducible phosphoprotein (OA48-18), mRNA. /FEA=mRNA /GEN=OA48-18 /PROD=acid-inducible phosphoprotein /DB_XREF=gi:5174618 /UG=Hs.278670 acid-inducible phosphoprotein /FL=gb:AF069250.1 gb:NM_006107.1 NM_006107 LUC7-like 3 (S. cerevisiae) LUC7L3 51747 NM_006107 /// NM_016424 /// XM_005257448 /// XM_005257449 /// XM_005257450 /// XM_005257451 /// XM_005257452 /// XM_005257454 /// XM_005257455 /// XM_006721943 /// XR_243663 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203805_s_at AW083279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW083279 /FEA=EST /DB_XREF=gi:6038431 /DB_XREF=est:xc07f04.x1 /CLONE=IMAGE:2583583 /UG=Hs.284153 Fanconi anemia, complementation group A /FL=gb:NM_000135.1 AW083279 Fanconi anemia, complementation group A FANCA 2175 NM_000135 /// NM_001018112 /// NM_001286167 /// XM_005256294 /// XM_006721167 /// XM_006721168 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203806_s_at NM_000135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000135.1 /DEF=Homo sapiens Fanconi anemia, complementation group A (FANCA), mRNA. /FEA=mRNA /GEN=FANCA /PROD=Fanconi anemia, complementation group A /DB_XREF=gi:4503654 /UG=Hs.284153 Fanconi anemia, complementation group A /FL=gb:NM_000135.1 NM_000135 Fanconi anemia, complementation group A FANCA 2175 NM_000135 /// NM_001018112 /// NM_001286167 /// XM_005256294 /// XM_006721167 /// XM_006721168 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203807_x_at NM_020991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020991.2 /DEF=Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA. /FEA=mRNA /GEN=CSH2 /PROD=chorionic somatomammotropin hormone 2, isoform 1precursor /DB_XREF=gi:12408690 /UG=Hs.306155 chorionic somatomammotropin hormone 2 /FL=gb:NM_020991.2 gb:BC002717.1 NM_020991 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSH2 /// CSHL1 /// GH1 1442 /// 1443 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_020991 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203808_at M95936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M95936.1 /DEF=Human protein-serinethreonine (AKT2) mRNA, complete cds. /FEA=mRNA /GEN=AKT2 /PROD=protein serinethreonine kinase /DB_XREF=gi:178325 /UG=Hs.326445 v-akt murine thymoma viral oncogene homolog 2 /FL=gb:M95936.1 gb:NM_001626.2 M95936 203809_s_at AA769075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA769075 /FEA=EST /DB_XREF=gi:2820313 /DB_XREF=est:oa74c11.s1 /CLONE=IMAGE:1318004 /UG=Hs.326445 v-akt murine thymoma viral oncogene homolog 2 /FL=gb:M95936.1 gb:NM_001626.2 AA769075 v-akt murine thymoma viral oncogene homolog 2 AKT2 208 NM_001243027 /// NM_001243028 /// NM_001626 /// XM_006723081 /// XM_006723082 /// XM_006723083 /// XM_006723084 /// XM_006723085 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0031340 // positive regulation of vesicle fusion // inferred from sequence or structural similarity /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0045444 // fat cell differentiation // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0065002 // intracellular protein transmembrane transport // inferred from sequence or structural similarity /// 0071156 // regulation of cell cycle arrest // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 203810_at BG252490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG252490 /FEA=EST /DB_XREF=gi:12762406 /DB_XREF=est:602366225F1 /CLONE=IMAGE:4474279 /UG=Hs.41693 DnaJ (Hsp40) homolog, subfamily B, member 4 /FL=gb:U40992.2 gb:NM_007034.2 BG252490 DnaJ (Hsp40) homolog, subfamily B, member 4 DNAJB4 11080 NM_007034 /// XM_005270397 /// XM_006710308 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0009408 // response to heat // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 203811_s_at NM_007034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007034.2 /DEF=Homo sapiens DnaJ-like heat shock protein 40 (HLJ1), mRNA. /FEA=mRNA /GEN=HLJ1 /PROD=DnaJ-like heat shock protein 40 /DB_XREF=gi:6631084 /UG=Hs.41693 DnaJ (Hsp40) homolog, subfamily B, member 4 /FL=gb:U40992.2 gb:NM_007034.2 NM_007034 DnaJ (Hsp40) homolog, subfamily B, member 4 DNAJB4 11080 NM_007034 /// XM_005270397 /// XM_006710308 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0009408 // response to heat // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 203812_at AB011538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011538.1 /DEF=Homo sapiens mRNA for MEGF5, partial cds. /FEA=mRNA /GEN=MEGF5 /PROD=MEGF5 /DB_XREF=gi:3449301 /UG=Hs.57929 slit (Drosophila) homolog 3 /FL=gb:NM_003062.1 gb:AB017169.1 AB011538 slit homolog 3 (Drosophila) SLIT3 6586 NM_001271946 /// NM_003062 /// XR_427809 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 203813_s_at NM_003062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003062.1 /DEF=Homo sapiens slit (Drosophila) homolog 3 (SLIT3), mRNA. /FEA=mRNA /GEN=SLIT3 /PROD=slit (Drosophila) homolog 3 /DB_XREF=gi:11321570 /UG=Hs.57929 slit (Drosophila) homolog 3 /FL=gb:NM_003062.1 gb:AB017169.1 NM_003062 slit homolog 3 (Drosophila) SLIT3 6586 NM_001271946 /// NM_003062 /// XR_427809 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 203814_s_at NM_000904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000904.1 /DEF=Homo sapiens NAD(P)H menadione oxidoreductase 2, dioxin-inducible (NMOR2), mRNA. /FEA=mRNA /GEN=NMOR2 /PROD=NAD(P)H menadione oxidoreductase 2,dioxin-inducible /DB_XREF=gi:4505416 /UG=Hs.73956 NAD(P)H menadione oxidoreductase 2, dioxin-inducible /FL=gb:J02888.1 gb:NM_000904.1 NM_000904 NAD(P)H dehydrogenase, quinone 2 NQO2 4835 NM_000904 /// NM_001290221 /// NM_001290222 /// XM_005249147 /// XM_005249148 /// XM_005249149 /// XM_005249150 /// XM_005249151 /// XM_005249152 /// XM_006715100 /// XM_006715101 0007613 // memory // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001512 // dihydronicotinamide riboside quinone reductase activity // inferred from electronic annotation /// 0008753 // NADPH dehydrogenase (quinone) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203815_at NM_000853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000853.1 /DEF=Homo sapiens glutathione S-transferase theta 1 (GSTT1), mRNA. /FEA=mRNA /GEN=GSTT1 /PROD=glutathione S-transferase theta 1 /DB_XREF=gi:4504184 /UG=Hs.77490 glutathione S-transferase theta 1 /FL=gb:NM_000853.1 NM_000853 glutathione S-transferase theta 1 GSTT1 2952 NM_000853 /// NM_001293807 /// NM_001293808 /// NM_001293809 /// NM_001293810 /// NM_001293811 /// NM_001293812 /// NM_001293813 /// NM_001293814 /// XM_005261587 /// XM_005261588 /// XM_005261589 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 203816_at NM_001929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001929.1 /DEF=Homo sapiens deoxyguanosine kinase (DGUOK), mRNA. /FEA=mRNA /GEN=DGUOK /PROD=deoxyguanosine kinase /DB_XREF=gi:4503318 /UG=Hs.77494 deoxyguanosine kinase /FL=gb:U41668.1 gb:NM_001929.1 NM_001929 deoxyguanosine kinase DGUOK 1716 NM_001929 /// NM_080915 /// NM_080916 /// NM_080917 /// NM_080918 /// XM_005264173 /// XM_005264174 /// XR_244926 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008617 // guanosine metabolic process // traceable author statement /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046070 // dGTP metabolic process // inferred from electronic annotation /// 0046122 // purine deoxyribonucleoside metabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004138 // deoxyguanosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded 203817_at W93728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W93728 /FEA=EST /DB_XREF=gi:1422918 /DB_XREF=est:zd96a11.s1 /CLONE=IMAGE:357308 /UG=Hs.77890 guanylate cyclase 1, soluble, beta 3 /FL=gb:NM_000857.1 W93728 guanylate cyclase 1, soluble, beta 3 GUCY1B3 2983 NM_000857 /// NM_001291951 /// NM_001291952 /// NM_001291953 /// NM_001291954 /// NM_001291955 /// XM_005262959 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0008074 // guanylate cyclase complex, soluble // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0043167 // ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from electronic annotation 203818_s_at NM_006802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006802.1 /DEF=Homo sapiens splicing factor 3a, subunit 3, 60kD (SF3A3), mRNA. /FEA=mRNA /GEN=SF3A3 /PROD=splicing factor 3a, subunit 3, 60kD /DB_XREF=gi:5803166 /UG=Hs.77897 splicing factor 3a, subunit 3, 60kD /FL=gb:BC002395.1 gb:U08815.1 gb:NM_006802.1 NM_006802 splicing factor 3a, subunit 3, 60kDa SF3A3 10946 NM_006802 /// XM_005270390 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203819_s_at AU160004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU160004 /FEA=EST /DB_XREF=gi:11021525 /DB_XREF=est:AU160004 /CLONE=Y79AA1000871 /UG=Hs.79440 IGF-II mRNA-binding protein 3 /FL=gb:U97188.1 gb:U76705.1 gb:AF117108.1 gb:NM_006547.1 AU160004 insulin-like growth factor 2 mRNA binding protein 3 IGF2BP3 10643 NM_006547 /// XM_006715638 /// XM_006715639 0006412 // translation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 203820_s_at NM_006547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006547.1 /DEF=Homo sapiens IGF-II mRNA-binding protein 3 (KOC1), mRNA. /FEA=mRNA /GEN=KOC1 /PROD=IGF-II mRNA-binding protein 3 /DB_XREF=gi:5729900 /UG=Hs.79440 IGF-II mRNA-binding protein 3 /FL=gb:U97188.1 gb:U76705.1 gb:AF117108.1 gb:NM_006547.1 NM_006547 insulin-like growth factor 2 mRNA binding protein 3 IGF2BP3 10643 NM_006547 /// XM_006715638 /// XM_006715639 0006412 // translation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 203821_at NM_001945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001945.1 /DEF=Homo sapiens diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) (DTR), mRNA. /FEA=mRNA /GEN=DTR /PROD=diphtheria toxin receptor (heparin-bindingepidermal growth factor-like growth factor) /DB_XREF=gi:4503412 /UG=Hs.799 diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) /FL=gb:M60278.1 gb:NM_001945.1 NM_001945 heparin-binding EGF-like growth factor HBEGF 1839 NM_001945 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051545 // negative regulation of elastin biosynthetic process // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype 203822_s_at NM_006874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006874.1 /DEF=Homo sapiens E74-like factor 2 (ets domain transcription factor) (ELF2), mRNA. /FEA=mRNA /GEN=ELF2 /PROD=new Ets-related factor /DB_XREF=gi:6857815 /UG=Hs.82143 E74-like factor 2 (ets domain transcription factor) /FL=gb:U43189.1 gb:NM_006874.1 NM_006874 E74-like factor 2 (ets domain transcription factor) ELF2 1998 NM_001276457 /// NM_001276458 /// NM_001276459 /// NM_006874 /// NM_201999 /// XM_005262803 /// XM_005262804 /// XM_005262805 /// XM_005262806 /// XM_006714128 /// XM_006714129 /// XM_006714130 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203823_at NM_021106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021106.1 /DEF=Homo sapiens regulator of G-protein signalling 3 (RGS3), mRNA. /FEA=mRNA /GEN=RGS3 /PROD=regulator of G-protein signalling 3 /DB_XREF=gi:10864074 /UG=Hs.82294 regulator of G-protein signalling 3 /FL=gb:NM_021106.1 gb:U27655.1 NM_021106 regulator of G-protein signaling 3 RGS3 5998 NM_001276260 /// NM_001276261 /// NM_001276262 /// NM_001282922 /// NM_001282923 /// NM_017790 /// NM_130795 /// NM_134427 /// NM_144488 /// NM_144489 /// XM_006717219 /// XM_006717220 /// XM_006717221 /// XM_006717222 /// XM_006717223 /// XM_006717224 /// XM_006717225 /// XM_006717226 /// XM_006717227 /// XM_006717228 /// XM_006717229 /// XM_006717230 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 203824_at NM_004616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004616.1 /DEF=Homo sapiens transmembrane 4 superfamily member 3 (TM4SF3), mRNA. /FEA=mRNA /GEN=TM4SF3 /PROD=transmembrane 4 superfamily member 3 /DB_XREF=gi:4759237 /UG=Hs.84072 transmembrane 4 superfamily member 3 /FL=gb:BC005246.1 gb:NM_004616.1 NM_004616 tetraspanin 8 TSPAN8 7103 NM_004616 /// XM_006719583 0006486 // protein glycosylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030195 // negative regulation of blood coagulation // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement 203825_at NM_007371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007371.2 /DEF=Homo sapiens bromodomain-containing 3 (BRD3), mRNA. /FEA=mRNA /GEN=BRD3 /PROD=bromodomain-containing protein 3 /DB_XREF=gi:12408642 /UG=Hs.86896 bromodomain-containing 3 /FL=gb:NM_007371.2 gb:D26362.1 NM_007371 bromodomain containing 3 BRD3 8019 NM_007371 /// XM_005272214 /// XM_006717291 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 203826_s_at NM_004910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004910.1 /DEF=Homo sapiens phosphatidylinositol transfer protein, membrane-associated (PITPNM), mRNA. /FEA=mRNA /GEN=PITPNM /PROD=phosphatidylinositol transfer protein,membrane-associated /DB_XREF=gi:4758925 /UG=Hs.93837 phosphatidylinositol transfer protein, membrane-associated /FL=gb:NM_004910.1 NM_004910 phosphatidylinositol transfer protein, membrane-associated 1 PITPNM1 9600 NM_001130848 /// NM_004910 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007602 // phototransduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203827_at NM_017983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017983.1 /DEF=Homo sapiens hypothetical protein FLJ10055 (FLJ10055), mRNA. /FEA=mRNA /GEN=FLJ10055 /PROD=hypothetical protein FLJ10055 /DB_XREF=gi:8922207 /UG=Hs.9398 hypothetical protein FLJ10055 /FL=gb:NM_017983.1 NM_017983 WD repeat domain, phosphoinositide interacting 1 WIPI1 55062 NM_017983 /// XM_005257497 0000045 // autophagic vacuole assembly // not recorded /// 0006914 // autophagy // inferred from expression pattern /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048203 // vesicle targeting, trans-Golgi to endosome // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0000407 // pre-autophagosomal structure // inferred from direct assay /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 203828_s_at NM_004221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004221.1 /DEF=Homo sapiens natural killer cell transcript 4 (NK4), mRNA. /FEA=mRNA /GEN=NK4 /PROD=natural killer cell transcript 4 /DB_XREF=gi:4758811 /UG=Hs.943 natural killer cell transcript 4 /FL=gb:M59807.1 gb:NM_004221.1 NM_004221 interleukin 32 IL32 9235 NM_001012631 /// NM_001012632 /// NM_001012633 /// NM_001012634 /// NM_001012635 /// NM_001012636 /// NM_001012718 /// NM_004221 /// XM_005255686 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203829_at NM_019040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019040.1 /DEF=Homo sapiens hypothetical protein (FLJ20498), mRNA. /FEA=mRNA /GEN=FLJ20498 /PROD=hypothetical protein /DB_XREF=gi:9506684 /UG=Hs.97925 hypothetical protein /FL=gb:AL136677.1 gb:NM_019040.1 NM_019040 elongator acetyltransferase complex subunit 4 ELP4 26610 NM_001288725 /// NM_001288726 /// NM_019040 /// XM_005252865 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred by curator /// 0016573 // histone acetylation // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay 203830_at NM_022344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022344.1 /DEF=Homo sapiens protein kinase Njmu-R1 (NJMU-R1), mRNA. /FEA=mRNA /GEN=NJMU-R1 /PROD=protein kinase Njmu-R1 /DB_XREF=gi:11641248 /UG=Hs.9800 protein kinase Njmu-R1 /FL=gb:AF305686.1 gb:NM_022344.1 NM_022344 chromosome 17 open reading frame 75 C17orf75 64149 NM_022344 /// XM_005258022 /// XM_005258023 /// XM_006722011 0007283 // spermatogenesis // non-traceable author statement 203831_at NM_014925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014925.1 /DEF=Homo sapiens KIAA1002 protein (KIAA1002), mRNA. /FEA=mRNA /GEN=KIAA1002 /PROD=KIAA1002 protein /DB_XREF=gi:7662441 /UG=Hs.102483 KIAA1002 protein /FL=gb:AB023219.1 gb:AF113695.1 gb:NM_014925.1 NM_014925 R3H domain containing 2 R3HDM2 22864 NM_014925 /// XM_005268711 /// XM_005268715 /// XM_005268722 /// XM_005268724 /// XM_005268725 /// XM_005268727 /// XM_005268728 /// XM_005268729 /// XM_006719277 /// XM_006719278 /// XM_006719279 /// XM_006719280 /// XM_006719281 /// XM_006719282 /// XM_006719283 /// XM_006719284 /// XM_006719285 /// XM_006719286 /// XM_006719287 /// XM_006719288 /// XM_006719289 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203832_at NM_003095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003095.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide F (SNRPF), mRNA. /FEA=mRNA /GEN=SNRPF /PROD=small nuclear ribonucleoprotein polypeptide F /DB_XREF=gi:4507130 /UG=Hs.105465 small nuclear ribonucleoprotein polypeptide F /FL=gb:BC002505.1 gb:NM_003095.1 NM_003095 small nuclear ribonucleoprotein polypeptide F SNRPF 6636 NM_003095 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 203833_s_at BF061845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF061845 /FEA=EST /DB_XREF=gi:10820755 /DB_XREF=est:7k67g05.x1 /CLONE=IMAGE:3480752 /UG=Hs.14894 trans-Golgi network protein (46, 48, 51kD isoforms) /FL=gb:U62390.1 gb:NM_006464.1 BF061845 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 203834_s_at NM_006464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006464.1 /DEF=Homo sapiens trans-Golgi network protein (46, 48, 51kD isoforms) (TGN51), mRNA. /FEA=mRNA /GEN=TGN51 /PROD=trans-Golgi network protein (46, 48, 51kDisoforms) /DB_XREF=gi:5454115 /UG=Hs.14894 trans-Golgi network protein (46, 48, 51kD isoforms) /FL=gb:U62390.1 gb:NM_006464.1 NM_006464 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 203835_at NM_005512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005512.1 /DEF=Homo sapiens glycoprotein A repetitions predominant (GARP), mRNA. /FEA=mRNA /GEN=GARP /PROD=glycoprotein A repetitions predominantprecursor /DB_XREF=gi:5031706 /UG=Hs.151641 glycoprotein A repetitions predominant /FL=gb:Z24680.1 gb:NM_005512.1 NM_005512 leucine rich repeat containing 32 LRRC32 2615 NM_001128922 /// NM_005512 /// XM_005273902 /// XM_005273903 /// XR_428911 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0034170 // toll-like receptor 11 signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0046007 // negative regulation of activated T cell proliferation // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203836_s_at D84476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D84476.1 /DEF=Homo sapiens mRNA for ASK1, complete cds. /FEA=mRNA /PROD=ASK1 /DB_XREF=gi:1805499 /UG=Hs.151988 mitogen-activated protein kinase kinase kinase 5 /FL=gb:U67156.1 gb:D84476.1 gb:NM_005923.2 D84476 mitogen-activated protein kinase kinase kinase 5 MAP3K5 4217 NM_005923 /// XM_005266990 /// XM_005266991 /// XM_005266992 /// XM_006715482 0000165 // MAPK cascade // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 1902911 // protein kinase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203837_at NM_005923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005923.2 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mRNA. /FEA=mRNA /GEN=MAP3K5 /PROD=MAPERK kinase kinase 5 /DB_XREF=gi:6031181 /UG=Hs.151988 mitogen-activated protein kinase kinase kinase 5 /FL=gb:U67156.1 gb:D84476.1 gb:NM_005923.2 NM_005923 mitogen-activated protein kinase kinase kinase 5 MAP3K5 4217 NM_005923 /// XM_005266990 /// XM_005266991 /// XM_005266992 /// XM_006715482 0000165 // MAPK cascade // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 1902911 // protein kinase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203838_s_at AI146308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI146308 /FEA=EST /DB_XREF=gi:3673990 /DB_XREF=est:qa03e05.x1 /CLONE=IMAGE:1685696 /UG=Hs.153937 activated p21cdc42Hs kinase /FL=gb:L13738.2 gb:NM_005781.2 AI146308 tyrosine kinase, non-receptor, 2 TNK2 10188 NM_001010938 /// NM_005781 /// XM_005269268 /// XM_005269269 /// XM_005269270 /// XM_005269271 /// XM_005269272 /// XM_005269273 /// XM_005269274 /// XM_005269275 /// XM_006713460 /// XM_006713461 /// XM_006713462 /// XM_006713463 /// XM_006713464 /// XM_006713465 /// XM_006713466 /// XM_006713467 /// XM_006713468 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070436 // Grb2-EGFR complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from sequence or structural similarity 203839_s_at NM_005781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005781.2 /DEF=Homo sapiens activated p21cdc42Hs kinase (ACK1), mRNA. /FEA=mRNA /GEN=ACK1 /PROD=activated p21cdc42Hs kinase /DB_XREF=gi:8922074 /UG=Hs.153937 activated p21cdc42Hs kinase /FL=gb:L13738.2 gb:NM_005781.2 NM_005781 tyrosine kinase, non-receptor, 2 TNK2 10188 NM_001010938 /// NM_005781 /// XM_005269268 /// XM_005269269 /// XM_005269270 /// XM_005269271 /// XM_005269272 /// XM_005269273 /// XM_005269274 /// XM_005269275 /// XM_006713460 /// XM_006713461 /// XM_006713462 /// XM_006713463 /// XM_006713464 /// XM_006713465 /// XM_006713466 /// XM_006713467 /// XM_006713468 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070436 // Grb2-EGFR complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from sequence or structural similarity 203840_at NM_003666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003666.1 /DEF=Homo sapiens basic leucine zipper nuclear factor 1 (JEM-1) (BLZF1), mRNA. /FEA=mRNA /GEN=BLZF1 /PROD=basic leucine zipper nuclear factor 1 (JEM-1) /DB_XREF=gi:4504804 /UG=Hs.158205 basic leucine zipper nuclear factor 1 (JEM-1) /FL=gb:U79751.1 gb:NM_003666.1 NM_003666 basic leucine zipper nuclear factor 1 BLZF1 8548 NM_003666 /// XM_005245561 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203841_x_at BG222594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG222594 /FEA=EST /DB_XREF=gi:12708115 /DB_XREF=est:naf78c05.x1 /CLONE=IMAGE:4170224 /UG=Hs.172740 microtubule-associated protein, RPEB family, member 3 /FL=gb:NM_012326.2 gb:AB025186.1 BG222594 microtubule-associated protein, RP/EB family, member 3 MAPRE3 22924 NM_012326 /// XM_006711967 /// XM_006711968 0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 203842_s_at NM_012326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012326.2 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 3 (MAPRE3), mRNA. /FEA=mRNA /GEN=MAPRE3 /PROD=microtubule-associated protein, RPEB family,member 3 /DB_XREF=gi:10800411 /UG=Hs.172740 microtubule-associated protein, RPEB family, member 3 /FL=gb:NM_012326.2 gb:AB025186.1 NM_012326 microtubule-associated protein, RP/EB family, member 3 MAPRE3 22924 NM_012326 /// XM_006711967 /// XM_006711968 0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 203843_at AA906056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA906056 /FEA=EST /DB_XREF=gi:3041179 /DB_XREF=est:oj90d06.s1 /CLONE=IMAGE:1505579 /UG=Hs.173965 ribosomal protein S6 kinase, 90kD, polypeptide 3 /FL=gb:U08316.1 gb:NM_004586.1 AA906056 ribosomal protein S6 kinase, 90kDa, polypeptide 3 RPS6KA3 6197 NM_004586 /// XM_005274573 /// XM_005274575 /// XM_005274576 /// XM_005274577 /// XM_006724505 /// XM_006724506 /// XM_006724507 0001501 // skeletal system development // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043555 // regulation of translation in response to stress // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203844_at NM_000551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000551.1 /DEF=Homo sapiens von Hippel-Lindau syndrome (VHL), mRNA. /FEA=mRNA /GEN=VHL /PROD=elogin binding protein /DB_XREF=gi:4507890 /UG=Hs.174007 von Hippel-Lindau syndrome /FL=gb:NM_000551.1 NM_000551 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase VHL 7428 NM_000551 /// NM_198156 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006508 // proteolysis // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050821 // protein stabilization // non-traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 203845_at AV727449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV727449 /FEA=EST /DB_XREF=gi:10836870 /DB_XREF=est:AV727449 /CLONE=HTCAYG01 /UG=Hs.199061 p300CBP-associated factor /FL=gb:U57317.2 gb:NM_003884.2 AV727449 K(lysine) acetyltransferase 2B KAT2B 8850 NM_003884 /// XM_005265528 /// XR_245162 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006473 // protein acetylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010835 // regulation of protein ADP-ribosylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0018394 // peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000125 // PCAF complex // non-traceable author statement /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0031672 // A band // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from sequence or structural similarity /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction 203846_at BC003154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003154.1 /DEF=Homo sapiens, TAT-INTERACTIVE PROTEIN, 72-KD, clone MGC:4116, mRNA, complete cds. /FEA=mRNA /PROD=TAT-INTERACTIVE PROTEIN, 72-KD /DB_XREF=gi:13111962 /UG=Hs.236218 TAT-INTERACTIVE PROTEIN, 72-KD /FL=gb:BC003154.1 gb:NM_012210.1 gb:U18543.1 BC003154 tripartite motif containing 32 TRIM32 22954 NM_001099679 /// NM_012210 /// XM_005251813 0000209 // protein polyubiquitination // inferred from direct assay /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from sequence or structural similarity /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000147 // positive regulation of cell motility // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005863 // striated muscle myosin thick filament // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // traceable author statement /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017022 // myosin binding // inferred from sequence or structural similarity /// 0030957 // Tat protein binding // traceable author statement /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203847_s_at AW341501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW341501 /FEA=EST /DB_XREF=gi:6838127 /DB_XREF=est:hd10e03.x1 /CLONE=IMAGE:2909116 /UG=Hs.25059 A kinase (PRKA) anchor protein 8 /FL=gb:NM_005858.1 AW341501 A kinase (PRKA) anchor protein 8 AKAP8 10270 NM_005858 /// XM_005259706 /// XR_244062 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203848_at AL050160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050160.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1222 (from clone DKFZp586B1222); partial cds. /FEA=mRNA /GEN=DKFZp586B1222 /PROD=hypothetical protein /DB_XREF=gi:4884373 /UG=Hs.25059 A kinase (PRKA) anchor protein 8 /FL=gb:NM_005858.1 AL050160 A kinase (PRKA) anchor protein 8 AKAP8 10270 NM_005858 /// XM_005259706 /// XR_244062 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203849_s_at BG473130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG473130 /FEA=EST /DB_XREF=gi:13405405 /DB_XREF=est:602515112F1 /CLONE=IMAGE:4646835 /UG=Hs.259873 axonal transport of synaptic vesicles /FL=gb:NM_004321.1 BG473130 kinesin family member 1A KIF1A 547 NM_001244008 /// NM_004321 /// XM_005247022 /// XM_005247023 /// XM_005247024 /// XM_005247026 /// XM_005247027 /// XM_005247028 /// XM_006712601 /// XM_006712602 /// XM_006712603 /// XM_006712604 /// XM_006712605 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203850_s_at NM_004321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004321.1 /DEF=Homo sapiens axonal transport of synaptic vesicles (ATSV), mRNA. /FEA=mRNA /GEN=ATSV /PROD=axonal transport of synaptic vesicles /DB_XREF=gi:4757821 /UG=Hs.259873 axonal transport of synaptic vesicles /FL=gb:NM_004321.1 NM_004321 kinesin family member 1A KIF1A 547 NM_001244008 /// NM_004321 /// XM_005247022 /// XM_005247023 /// XM_005247024 /// XM_005247026 /// XM_005247027 /// XM_005247028 /// XM_006712601 /// XM_006712602 /// XM_006712603 /// XM_006712604 /// XM_006712605 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203851_at NM_002178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002178.1 /DEF=Homo sapiens insulin-like growth factor binding protein 6 (IGFBP6), mRNA. /FEA=mRNA /GEN=IGFBP6 /PROD=insulin-like growth factor binding protein 6 /DB_XREF=gi:11321592 /UG=Hs.274313 insulin-like growth factor binding protein 6 /FL=gb:NM_002178.1 gb:BC003507.1 gb:BC005007.1 gb:M62402.1 NM_002178 insulin-like growth factor binding protein 6 IGFBP6 3489 NM_002178 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from electronic annotation 203852_s_at NM_000344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000344.2 /DEF=Homo sapiens survival of motor neuron 1, telomeric (SMN1), transcript variant d, mRNA. /FEA=mRNA /GEN=SMN1 /PROD=survival of motor neuron 1, telomeric isoform d /DB_XREF=gi:13259515 /UG=Hs.288986 survival of motor neuron 1, telomeric /FL=gb:NM_000344.2 gb:U18423.1 NM_000344 survival of motor neuron 1, telomeric /// survival of motor neuron 2, centromeric SMN1 /// SMN2 6606 /// 6607 NM_000344 /// NM_017411 /// NM_022874 /// NM_022875 /// NM_022876 /// NM_022877 /// XM_005248575 /// XM_005276775 /// XM_006714677 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 203853_s_at NM_012296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012296.1 /DEF=Homo sapiens GRB2-associated binding protein 2 (GAB2), mRNA. /FEA=mRNA /GEN=GAB2 /PROD=GRB2-associated binding protein 2 /DB_XREF=gi:6912459 /UG=Hs.30687 GRB2-associated binding protein 2 /FL=gb:AB011143.1 gb:NM_012296.1 NM_012296 GRB2-associated binding protein 2 GAB2 9846 NM_012296 /// NM_080491 /// XM_006718753 /// XR_428935 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from reviewed computational analysis /// 0016477 // cell migration // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from reviewed computational analysis /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from sequence or structural similarity 203854_at NM_000204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000204.1 /DEF=Homo sapiens I factor (complement) (IF), mRNA. /FEA=mRNA /GEN=IF /PROD=I factor (complement) /DB_XREF=gi:4504578 /UG=Hs.36602 I factor (complement) /FL=gb:J02770.1 gb:NM_000204.1 NM_000204 complement factor I CFI 3426 NM_000204 /// XM_005262975 /// XM_005262976 /// XM_006714209 /// XM_006714210 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203855_at NM_014969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014969.1 /DEF=Homo sapiens KIAA0893 protein (KIAA0893), mRNA. /FEA=mRNA /GEN=KIAA0893 /PROD=KIAA0893 protein /DB_XREF=gi:7662363 /UG=Hs.3830 KIAA0893 protein /FL=gb:AB020700.1 gb:NM_014969.1 NM_014969 WD repeat domain 47 WDR47 22911 NM_001142550 /// NM_001142551 /// NM_014969 /// XM_006710460 /// XM_006710461 0007275 // multicellular organismal development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203856_at NM_003384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003384.1 /DEF=Homo sapiens vaccinia related kinase 1 (VRK1), mRNA. /FEA=mRNA /GEN=VRK1 /PROD=vaccinia related kinase 1 /DB_XREF=gi:4507902 /UG=Hs.48269 vaccinia related kinase 1 /FL=gb:AB000449.1 gb:NM_003384.1 NM_003384 vaccinia related kinase 1 VRK1 7443 NM_003384 /// XM_005268041 /// XM_006720247 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043987 // histone H3-S10 phosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0072355 // histone H3-T3 phosphorylation // inferred from direct assay /// 0090166 // Golgi disassembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031493 // nucleosomal histone binding // inferred from physical interaction /// 0035175 // histone kinase activity (H3-S10 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0072354 // histone kinase activity (H3-T3 specific) // inferred from direct assay 203857_s_at NM_006810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006810.1 /DEF=Homo sapiens for protein disulfide isomerase-related (PDIR), mRNA. /FEA=mRNA /GEN=PDIR /PROD=for protein disulfide isomerase-related /DB_XREF=gi:5803120 /UG=Hs.76901 for protein disulfide isomerase-related /FL=gb:D49490.1 gb:NM_006810.1 NM_006810 microRNA 7110 /// protein disulfide isomerase family A, member 5 MIR7110 /// PDIA5 10954 /// 102465667 NM_006810 /// NR_028444 /// NR_106960 /// XR_427359 /// XR_427360 0006457 // protein folding // not recorded /// 0006457 // protein folding // traceable author statement /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003756 // protein disulfide isomerase activity // not recorded /// 0003756 // protein disulfide isomerase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation 203858_s_at NM_001303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001303.1 /DEF=Homo sapiens COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A: farnesyltransferase) (COX10), mRNA. /FEA=mRNA /GEN=COX10 /PROD=COX10 (yeast) homolog, cytochrome c oxidaseassembly protein (heme A: farnesyltransferase) /DB_XREF=gi:4502978 /UG=Hs.77513 COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A: farnesyltransferase) /FL=gb:BC000060.1 gb:NM_001303.1 gb:U09466.1 NM_001303 cytochrome c oxidase assembly homolog 10 (yeast) COX10 1352 NM_001303 /// XM_005256458 /// XM_005256459 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006123 // mitochondrial electron transport, cytochrome c to oxygen // inferred by curator /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006784 // heme a biosynthetic process // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from mutant phenotype /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0017004 // cytochrome complex assembly // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from genetic interaction /// 0048034 // heme O biosynthetic process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from mutant phenotype 0005739 // mitochondrion // inferred by curator /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from mutant phenotype /// 0004311 // farnesyltranstransferase activity // traceable author statement /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0008495 // protoheme IX farnesyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203859_s_at NM_002579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002579.1 /DEF=Homo sapiens paralemmin (PALM), mRNA. /FEA=mRNA /GEN=PALM /PROD=paralemmin /DB_XREF=gi:4557041 /UG=Hs.78482 paralemmin /FL=gb:NM_002579.1 NM_002579 paralemmin PALM 5064 NM_001040134 /// NM_002579 /// XM_005259565 /// XM_005259566 /// XM_006722761 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0008104 // protein localization // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0060074 // synapse maturation // inferred from electronic annotation /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044309 // neuron spine // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031750 // D3 dopamine receptor binding // inferred from electronic annotation 203860_at NM_000282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000282.1 /DEF=Homo sapiens propionyl Coenzyme A carboxylase, alpha polypeptide (PCCA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PCCA /PROD=Propionyl-Coenzyme A carboxylase, alphapolypeptide precursor /DB_XREF=gi:4557832 /UG=Hs.80741 propionyl Coenzyme A carboxylase, alpha polypeptide /FL=gb:BC000140.1 gb:NM_000282.1 NM_000282 propionyl CoA carboxylase, alpha polypeptide PCCA 5095 NM_000282 /// NM_001127692 /// NM_001178004 /// XM_005254059 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0004658 // propionyl-CoA carboxylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0009374 // biotin binding // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203861_s_at AU146889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146889 /FEA=EST /DB_XREF=gi:11008410 /DB_XREF=est:AU146889 /CLONE=HEMBB1001793 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1 AU146889 actinin, alpha 2 ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203862_s_at H16245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H16245 /FEA=EST /DB_XREF=gi:881065 /DB_XREF=est:ym13c09.s1 /CLONE=IMAGE:47741 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1 H16245 actinin, alpha 2 ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203863_at W63731 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W63731 /FEA=EST /DB_XREF=gi:1371311 /DB_XREF=est:zd30b05.s1 /CLONE=IMAGE:342129 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1 W63731 actinin, alpha 2 ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203864_s_at NM_001103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001103.1 /DEF=Homo sapiens actinin, alpha 2 (ACTN2), mRNA. /FEA=mRNA /GEN=ACTN2 /PROD=actinin, alpha 2 /DB_XREF=gi:4501892 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1 NM_001103 actinin, alpha 2 ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203865_s_at NM_015833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015833.1 /DEF=Homo sapiens adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) (ADARB1), transcript variant DRABA2b, mRNA. /FEA=mRNA /GEN=ADARB1 /PROD=RNA-specific adenosine deaminase B1, isoformDRABA2b /DB_XREF=gi:7669476 /UG=Hs.85302 adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) /FL=gb:U82121.1 gb:U76421.1 gb:NM_015833.1 NM_015833 adenosine deaminase, RNA-specific, B1 ADARB1 104 NM_001033049 /// NM_001112 /// NM_001160230 /// NM_015833 /// NM_015834 /// NR_027672 /// NR_027673 /// NR_027674 /// NR_073200 /// XM_006723953 /// XM_006723954 /// XM_006723955 /// XM_006723956 /// XM_006723957 /// XM_006723958 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred by curator /// 0016556 // mRNA modification // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203866_at AJ005257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ005257.1 /DEF=Homo sapiens partial mRNA for beta-transducin family protein (putative). /FEA=mRNA /DB_XREF=gi:3043442 /UG=Hs.85570 hypothetical protein similar to beta-transducin family /FL=gb:NM_018096.1 AJ005257 notchless homolog 1 (Drosophila) NLE1 54475 NM_001014445 /// NM_018096 /// XM_005257989 /// XM_005257992 /// XM_006721956 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203867_s_at NM_018096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018096.1 /DEF=Homo sapiens hypothetical protein similar to beta-transducin family (FLJ10458), mRNA. /FEA=mRNA /GEN=FLJ10458 /PROD=hypothetical protein similar to beta-transducinfamily /DB_XREF=gi:8922427 /UG=Hs.85570 hypothetical protein similar to beta-transducin family /FL=gb:NM_018096.1 NM_018096 notchless homolog 1 (Drosophila) NLE1 54475 NM_001014445 /// NM_018096 /// XM_005257989 /// XM_005257992 /// XM_006721956 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203868_s_at NM_001078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001078.1 /DEF=Homo sapiens vascular cell adhesion molecule 1 (VCAM1), mRNA. /FEA=mRNA /GEN=VCAM1 /PROD=vascular cell adhesion molecule 1 /DB_XREF=gi:4507874 /UG=Hs.109225 vascular cell adhesion molecule 1 /FL=gb:M60335.1 gb:NM_001078.1 NM_001078 vascular cell adhesion molecule 1 VCAM1 7412 NM_001078 /// NM_001199834 /// NM_080682 0001666 // response to hypoxia // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009308 // amine metabolic process // inferred from direct assay /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation 0002102 // podosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071065 // alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008131 // primary amine oxidase activity // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 203869_at AK024318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024318.1 /DEF=Homo sapiens cDNA FLJ14256 fis, clone PLACE1000007, weakly similar to PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE R10E11.3 (EC 3.1.2.15). /FEA=mRNA /DB_XREF=gi:10436669 /UG=Hs.109268 hypothetical protein FLJ12552 /FL=gb:NM_022832.1 AK024318 ubiquitin specific peptidase 46 USP46 64854 NM_001134223 /// NM_001286767 /// NM_001286768 /// NM_022832 0001662 // behavioral fear response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007610 // behavior // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 203870_at BE856374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856374 /FEA=EST /DB_XREF=gi:10369335 /DB_XREF=est:7f93f06.x1 /CLONE=IMAGE:3304547 /UG=Hs.109268 hypothetical protein FLJ12552 /FL=gb:NM_022832.1 BE856374 ubiquitin specific peptidase 46 USP46 64854 NM_001134223 /// NM_001286767 /// NM_001286768 /// NM_022832 0001662 // behavioral fear response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007610 // behavior // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 203871_at NM_015670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015670.1 /DEF=Homo sapiens sentrinSUMO-specific protease 3 (SENP3), mRNA. /FEA=mRNA /GEN=SENP3 /PROD=sentrinSUMO-specific protease 3 /DB_XREF=gi:7661681 /UG=Hs.118926 sentrinSUMO-specific protease 3 /FL=gb:AY008763.1 gb:AL050283.1 gb:NM_015670.1 NM_015670 SUMO1/sentrin/SMT3 specific peptidase 3 SENP3 26168 NM_015670 0006508 // proteolysis // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203872_at NM_001100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001100.2 /DEF=Homo sapiens actin, alpha 1, skeletal muscle (ACTA1), mRNA. /FEA=mRNA /GEN=ACTA1 /PROD=alpha 1 actin precursor /DB_XREF=gi:5016087 /UG=Hs.1288 actin, alpha 1, skeletal muscle /FL=gb:NM_001100.2 NM_001100 actin, alpha 1, skeletal muscle ACTA1 58 NM_001100 0006936 // muscle contraction // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009991 // response to extracellular stimulus // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030240 // skeletal muscle thin filament assembly // inferred from mutant phenotype /// 0043503 // skeletal muscle fiber adaptation // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005865 // striated muscle thin filament // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0017022 // myosin binding // traceable author statement /// 0043531 // ADP binding // traceable author statement 203873_at M88163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M88163.1 /DEF=Human global transcription activator homologous sequence mRNA, complete cds. /FEA=mRNA /PROD=transcription activator /DB_XREF=gi:292495 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1 M88163 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay 203874_s_at NM_003069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003069.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (SMARCA1), mRNA. /FEA=mRNA /GEN=SMARCA1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 1 /DB_XREF=gi:4507066 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1 NM_003069 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay 203875_at NM_003069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003069.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (SMARCA1), mRNA. /FEA=mRNA /GEN=SMARCA1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 1 /DB_XREF=gi:4507066 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1 NM_003069 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay 203876_s_at AI761713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761713 /FEA=EST /DB_XREF=gi:5177469 /DB_XREF=est:wg67d12.x1 /CLONE=IMAGE:2370167 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2 AI761713 matrix metallopeptidase 11 (stromelysin 3) MMP11 4320 NM_005940 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203877_at NM_005940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005940.2 /DEF=Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11), mRNA. /FEA=mRNA /GEN=MMP11 /PROD=matrix metalloproteinase 11 preproprotein /DB_XREF=gi:13027795 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2 NM_005940 203878_s_at NM_005940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005940.2 /DEF=Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11), mRNA. /FEA=mRNA /GEN=MMP11 /PROD=matrix metalloproteinase 11 preproprotein /DB_XREF=gi:13027795 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2 NM_005940 matrix metallopeptidase 11 (stromelysin 3) MMP11 4320 NM_005940 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203879_at U86453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U86453.1 /DEF=Human phosphatidylinositol 3-kinase catalytic subunit p110delta mRNA, complete cds. /FEA=mRNA /PROD=phosphatidylinositol 3-kinase catalytic subunitp110delta /DB_XREF=gi:2317893 /UG=Hs.162808 phosphoinositide-3-kinase, catalytic, delta polypeptide /FL=gb:U86453.1 gb:NM_005026.1 U86453 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta PIK3CD 5293 NM_005026 /// XM_005263473 /// XM_006710686 /// XM_006710687 /// XM_006710688 /// XM_006710689 /// XM_006710690 0001779 // natural killer cell differentiation // traceable author statement /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // traceable author statement /// 0002679 // respiratory burst involved in defense response // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010818 // T cell chemotaxis // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030101 // natural killer cell activation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0035747 // natural killer cell chemotaxis // traceable author statement /// 0035754 // B cell chemotaxis // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0043303 // mast cell degranulation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // traceable author statement /// 0060374 // mast cell differentiation // traceable author statement /// 0072672 // neutrophil extravasation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0042629 // mast cell granule // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 203880_at NM_005694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005694.1 /DEF=Homo sapiens COX17 (yeast) homolog, cytochrome c oxidase assembly protein (COX17), mRNA. /FEA=mRNA /GEN=COX17 /PROD=COX17 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:5031644 /UG=Hs.16297 COX17 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:L77701.1 gb:NM_005694.1 NM_005694 COX17 cytochrome c oxidase copper chaperone /// popeye domain containing 2 COX17 /// POPDC2 10063 /// 64091 NM_005694 /// NM_022135 /// XM_005247698 /// XM_005247699 /// XR_241504 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005507 // copper ion binding // traceable author statement /// 0016531 // copper chaperone activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203881_s_at NM_004010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004010.1 /DEF=Homo sapiens dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 (DMD), transcript variant Dp427p2, mRNA. /FEA=mRNA /GEN=DMD /PROD=dystrophin Dp427p2 isoform /DB_XREF=gi:5032314 /UG=Hs.169470 dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 /FL=gb:NM_004010.1 NM_004010 dystrophin DMD 1756 NM_000109 /// NM_004006 /// NM_004007 /// NM_004009 /// NM_004010 /// NM_004011 /// NM_004012 /// NM_004013 /// NM_004014 /// NM_004015 /// NM_004016 /// NM_004017 /// NM_004018 /// NM_004019 /// NM_004020 /// NM_004021 /// NM_004022 /// NM_004023 /// XM_006724468 /// XM_006724469 /// XM_006724470 /// XM_006724471 /// XM_006724472 /// XM_006724473 /// XM_006724474 /// XM_006724475 /// XM_006724476 /// XR_430491 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014819 // regulation of skeletal muscle contraction // inferred from sequence or structural similarity /// 0014904 // myotube cell development // inferred from electronic annotation /// 0021629 // olfactory nerve structural organization // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity /// 0044458 // motile cilium assembly // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051647 // nucleus localization // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060857 // establishment of glial blood-brain barrier // inferred from electronic annotation /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0090287 // regulation of cellular response to growth factor stimulus // inferred from mutant phenotype /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 2000169 // regulation of peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // non-traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0017022 // myosin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from sequence or structural similarity 203882_at NM_006084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006084.1 /DEF=Homo sapiens interferon-stimulated transcription factor 3, gamma (48kD) (ISGF3G), mRNA. /FEA=mRNA /GEN=ISGF3G /PROD=interferon-stimulated transcription factor 3,gamma (48kD) /DB_XREF=gi:5174474 /UG=Hs.1706 interferon-stimulated transcription factor 3, gamma (48kD) /FL=gb:M87503.1 gb:NM_006084.1 NM_006084 interferon regulatory factor 9 IRF9 10379 NM_006084 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0023035 // CD40 signaling pathway // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0097039 // protein linear polyubiquitination // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0071797 // LUBAC complex // inferred from direct assay /// 0071797 // LUBAC complex // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203883_s_at BG249608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG249608 /FEA=EST /DB_XREF=gi:12759411 /DB_XREF=est:602319671F1 /CLONE=IMAGE:4415033 /UG=Hs.173656 KIAA0941 protein /FL=gb:AB023158.1 gb:NM_014904.1 BG249608 RAB11 family interacting protein 2 (class I) RAB11FIP2 22841 NM_014904 /// XM_005269629 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from mutant phenotype /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203884_s_at NM_014904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014904.1 /DEF=Homo sapiens KIAA0941 protein (KIAA0941), mRNA. /FEA=mRNA /GEN=KIAA0941 /PROD=KIAA0941 protein /DB_XREF=gi:7662393 /UG=Hs.173656 KIAA0941 protein /FL=gb:AB023158.1 gb:NM_014904.1 NM_014904 RAB11 family interacting protein 2 (class I) RAB11FIP2 22841 NM_014904 /// XM_005269629 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from mutant phenotype /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203885_at NM_014999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014999.1 /DEF=Homo sapiens KIAA0118 protein (KIAA0118), mRNA. /FEA=mRNA /GEN=KIAA0118 /PROD=KIAA0118 protein /DB_XREF=gi:7661921 /UG=Hs.184627 KIAA0118 protein /FL=gb:AF091035.1 gb:NM_014999.1 NM_014999 RAB21, member RAS oncogene family RAB21 23011 NM_014999 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 203886_s_at NM_001998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001998.1 /DEF=Homo sapiens fibulin 2 (FBLN2), mRNA. /FEA=mRNA /GEN=FBLN2 /PROD=fibulin 2 precursor /DB_XREF=gi:4503664 /UG=Hs.198862 fibulin 2 /FL=gb:NM_001998.1 NM_001998 fibulin 2 FBLN2 2199 NM_001004019 /// NM_001165035 /// NM_001998 /// XM_006713026 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 203887_s_at NM_000361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000361.1 /DEF=Homo sapiens thrombomodulin (THBD), mRNA. /FEA=mRNA /GEN=THBD /PROD=thrombomodulin /DB_XREF=gi:4507482 /UG=Hs.2030 thrombomodulin /FL=gb:M16552.1 gb:NM_000361.1 NM_000361 thrombomodulin THBD 7056 NM_000361 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 203888_at NM_000361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000361.1 /DEF=Homo sapiens thrombomodulin (THBD), mRNA. /FEA=mRNA /GEN=THBD /PROD=thrombomodulin /DB_XREF=gi:4507482 /UG=Hs.2030 thrombomodulin /FL=gb:M16552.1 gb:NM_000361.1 NM_000361 thrombomodulin THBD 7056 NM_000361 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 203889_at NM_003020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003020.1 /DEF=Homo sapiens secretory granule, neuroendocrine protein 1 (7B2 protein) (SGNE1), mRNA. /FEA=mRNA /GEN=SGNE1 /PROD=secretory granule, neuroendocrine protein 1 (7B2protein) /DB_XREF=gi:4506916 /UG=Hs.2265 secretory granule, neuroendocrine protein 1 (7B2 protein) /FL=gb:BC005349.1 gb:NM_003020.1 NM_003020 secretogranin V (7B2 protein) SCG5 6447 NM_001144757 /// NM_003020 /// XM_005254595 /// XM_005254596 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0046883 // regulation of hormone secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from direct assay 203890_s_at BF686824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF686824 /FEA=EST /DB_XREF=gi:11972232 /DB_XREF=est:602140792F1 /CLONE=IMAGE:4301998 /UG=Hs.25619 death-associated protein kinase 3 /FL=gb:AB007144.1 gb:NM_001348.1 gb:AB022341.1 BF686824 death-associated protein kinase 3 /// microRNA 637 DAPK3 /// MIR637 1613 /// 693222 NM_001348 /// NR_030367 /// XM_005259508 /// XM_005259509 0000910 // cytokinesis // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 203891_s_at NM_001348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001348.1 /DEF=Homo sapiens death-associated protein kinase 3 (DAPK3), mRNA. /FEA=mRNA /GEN=DAPK3 /PROD=death-associated protein kinase 3 /DB_XREF=gi:4557510 /UG=Hs.25619 death-associated protein kinase 3 /FL=gb:AB007144.1 gb:NM_001348.1 gb:AB022341.1 NM_001348 death-associated protein kinase 3 /// microRNA 637 DAPK3 /// MIR637 1613 /// 693222 NM_001348 /// NR_030367 /// XM_005259508 /// XM_005259509 0000910 // cytokinesis // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 203892_at NM_006103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006103.1 /DEF=Homo sapiens epididymis-specific, whey-acidic protein type, four-disulfide core; putative ovarian carcinoma marker (HE4), mRNA. /FEA=mRNA /GEN=HE4 /PROD=epididymis-specific, whey-acidic protein type,four-disulfide core; putative ovarian carcinoma marker /DB_XREF=gi:5174454 /UG=Hs.2719 epididymis-specific, whey-acidic protein type, four-disulfide core; putative ovarian carcinoma marker /FL=gb:NM_006103.1 NM_006103 WAP four-disulfide core domain 2 WFDC2 10406 NM_006103 /// NM_080733 /// NM_080734 /// NM_080735 /// NM_080736 0006508 // proteolysis // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0019828 // aspartic-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203893_at NM_016283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016283.1 /DEF=Homo sapiens adrenal gland protein AD-004 (LOC51578), mRNA. /FEA=mRNA /GEN=LOC51578 /PROD=adrenal gland protein AD-004 /DB_XREF=gi:7706211 /UG=Hs.279586 adrenal gland protein AD-004 /FL=gb:AF151895.1 gb:AF110777.1 gb:NM_016283.1 NM_016283 adenylate kinase 6 AK6 102157402 NM_001015891 /// NM_016283 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060760 // positive regulation of response to cytokine stimulus // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 203894_at NM_016437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016437.1 /DEF=Homo sapiens tubulin, gamma 2 (TUBG2), mRNA. /FEA=mRNA /GEN=TUBG2 /PROD=tubulin, gamma 2 /DB_XREF=gi:7706750 /UG=Hs.279669 tubulin, gamma 2 /FL=gb:AF225971.1 gb:NM_016437.1 NM_016437 tubulin, gamma 2 TUBG2 27175 NM_016437 /// XM_005257222 /// XM_005257223 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007020 // microtubule nucleation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0000930 // gamma-tubulin complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 203895_at AL535113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL535113 /FEA=EST /DB_XREF=gi:12798606 /DB_XREF=est:AL535113 /CLONE=CS0DF008YC23 (3 prime) /UG=Hs.283006 phospholipase C, beta 4 /FL=gb:NM_000933.1 gb:L41349.1 AL535113 phospholipase C, beta 4 PLCB4 5332 NM_000933 /// NM_001172646 /// NM_182797 /// XM_005260724 /// XM_005260728 /// XM_006723568 /// XM_006723569 /// XM_006723570 /// XM_006723571 /// XM_006723572 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203896_s_at NM_000933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000933.1 /DEF=Homo sapiens phospholipase C, beta 4 (PLCB4), mRNA. /FEA=mRNA /GEN=PLCB4 /PROD=phospholipase C, beta 4 /DB_XREF=gi:4505866 /UG=Hs.283006 phospholipase C, beta 4 /FL=gb:NM_000933.1 gb:L41349.1 NM_000933 phospholipase C, beta 4 PLCB4 5332 NM_000933 /// NM_001172646 /// NM_182797 /// XM_005260724 /// XM_005260728 /// XM_006723568 /// XM_006723569 /// XM_006723570 /// XM_006723571 /// XM_006723572 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203897_at BE963444 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963444 /FEA=EST /DB_XREF=gi:11766863 /DB_XREF=est:601657224R1 /CLONE=IMAGE:3866357 /UG=Hs.28607 hypothetical protein A-211C6.1 /FL=gb:NM_020424.1 BE963444 LYR motif containing 1 LYRM1 57149 NM_001128301 /// NM_001128302 /// NM_020424 /// XM_005255444 /// XM_005255445 /// XM_006721070 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 203898_at AU154853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154853 /FEA=EST /DB_XREF=gi:11016374 /DB_XREF=est:AU154853 /CLONE=OVARC1000240 /UG=Hs.300684 calcitonin gene-related peptide-receptor component protein /FL=gb:BC000783.1 gb:AF073792.1 gb:U51134.1 gb:NM_014478.1 AU154853 CGRP receptor component CRCP 27297 NM_001040647 /// NM_001040648 /// NM_001142414 /// NM_014478 /// NR_024548 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007340 // acrosome reaction // non-traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009360 // DNA polymerase III complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // non-traceable author statement 203899_s_at NM_014478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014478.1 /DEF=Homo sapiens calcitonin gene-related peptide-receptor component protein (CGRP-RCP), mRNA. /FEA=mRNA /GEN=CGRP-RCP /PROD=calcitonin gene-related peptide-receptorcomponent protein /DB_XREF=gi:7656976 /UG=Hs.300684 calcitonin gene-related peptide-receptor component protein /FL=gb:BC000783.1 gb:AF073792.1 gb:U51134.1 gb:NM_014478.1 NM_014478 CGRP receptor component CRCP 27297 NM_001040647 /// NM_001040648 /// NM_001142414 /// NM_014478 /// NR_024548 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007340 // acrosome reaction // non-traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009360 // DNA polymerase III complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // non-traceable author statement 203900_at NM_024547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024547.1 /DEF=Homo sapiens KIAA0467 protein (KIAA0467), mRNA. /FEA=mRNA /GEN=KIAA0467 /PROD=hypothetical protein FLJ23425 /DB_XREF=gi:13386459 /UG=Hs.301943 KIAA0467 protein /FL=gb:NM_024547.1 NM_024547 seizure threshold 2 homolog (mouse) SZT2 23334 NM_001012960 /// NM_001012961 /// NM_015284 /// NM_182518 /// XM_005270686 /// XM_006710501 /// XM_006710502 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from electronic annotation /// 1901668 // regulation of superoxide dismutase activity // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 203901_at NM_006116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006116.1 /DEF=Homo sapiens transforming growth factor beta-activated kinase-binding protein 1 (TAB1), mRNA. /FEA=mRNA /GEN=TAB1 /PROD=transforming growth factor beta-activatedkinase-binding protein 1 /DB_XREF=gi:5174702 /UG=Hs.31472 transforming growth factor beta-activated kinase-binding protein 1 /FL=gb:U49928.1 gb:NM_006116.1 NM_006116 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TAB1 10454 NM_006116 /// NM_153497 0000185 // activation of MAPKKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from electronic annotation 203902_at AU148222 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148222 /FEA=EST /DB_XREF=gi:11009743 /DB_XREF=est:AU148222 /CLONE=MAMMA1002938 /UG=Hs.31720 hephaestin /FL=gb:AB014598.1 gb:NM_014799.1 AU148222 hephaestin HEPH 9843 NM_001130860 /// NM_001282141 /// NM_014799 /// NM_138737 /// XM_006724719 /// XM_006724720 /// XM_006724721 /// XM_006724722 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004322 // ferroxidase activity // inferred from mutant phenotype /// 0005507 // copper ion binding // inferred from mutant phenotype /// 0008198 // ferrous iron binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203903_s_at NM_014799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014799.1 /DEF=Homo sapiens hephaestin (HEPH), mRNA. /FEA=mRNA /GEN=HEPH /PROD=hephaestin /DB_XREF=gi:7662253 /UG=Hs.31720 hephaestin /FL=gb:AB014598.1 gb:NM_014799.1 NM_014799 hephaestin HEPH 9843 NM_001130860 /// NM_001282141 /// NM_014799 /// NM_138737 /// XM_006724719 /// XM_006724720 /// XM_006724721 /// XM_006724722 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004322 // ferroxidase activity // inferred from mutant phenotype /// 0005507 // copper ion binding // inferred from mutant phenotype /// 0008198 // ferrous iron binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203904_x_at NM_002231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002231.2 /DEF=Homo sapiens kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) (KAI1), mRNA. /FEA=mRNA /GEN=KAI1 /PROD=kangai 1 /DB_XREF=gi:13259537 /UG=Hs.323949 kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) /FL=gb:BC000726.1 gb:BC001821.1 gb:NM_002231.2 gb:U20770.1 NM_002231 CD82 molecule CD82 3732 NM_001024844 /// NM_002231 /// XM_006718222 /// XM_006718223 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203905_at NM_002582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002582.1 /DEF=Homo sapiens poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), mRNA. /FEA=mRNA /GEN=PARN /PROD=poly(A)-specific ribonuclease (deadenylationnuclease) /DB_XREF=gi:4505610 /UG=Hs.43445 poly(A)-specific ribonuclease (deadenylation nuclease) /FL=gb:NM_002582.1 NM_002582 poly(A)-specific ribonuclease PARN 5073 NM_001134477 /// NM_001242992 /// NM_002582 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006402 // mRNA catabolic process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009451 // RNA modification // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // traceable author statement /// 0004518 // nuclease activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203906_at AI652645 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652645 /FEA=EST /DB_XREF=gi:4736624 /DB_XREF=est:wb30b07.x1 /CLONE=IMAGE:2307157 /UG=Hs.4764 KIAA0763 gene product /FL=gb:AB018306.1 gb:NM_014869.1 AI652645 IQ motif and Sec7 domain 1 IQSEC1 9922 NM_001134382 /// NM_014869 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203907_s_at NM_014869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014869.1 /DEF=Homo sapiens KIAA0763 gene product (KIAA0763), mRNA. /FEA=mRNA /GEN=KIAA0763 /PROD=KIAA0763 gene product /DB_XREF=gi:7662289 /UG=Hs.4764 KIAA0763 gene product /FL=gb:AB018306.1 gb:NM_014869.1 NM_014869 IQ motif and Sec7 domain 1 IQSEC1 9922 NM_001134382 /// NM_014869 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203908_at NM_003759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003759.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), mRNA. /FEA=mRNA /GEN=SLC4A4 /PROD=solute carrier family 4, sodium bicarbonatecotransporter, member 4 /DB_XREF=gi:4507024 /UG=Hs.5462 solute carrier family 4, sodium bicarbonate cotransporter, member 4 /FL=gb:AF007216.1 gb:NM_003759.1 NM_003759 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 SLC4A4 8671 NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 203909_at NM_006359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006359.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 6 (SLC9A6), mRNA. /FEA=mRNA /GEN=SLC9A6 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 6 /DB_XREF=gi:5454069 /UG=Hs.62185 solute carrier family 9 (sodiumhydrogen exchanger), isoform 6 /FL=gb:AF030409.1 gb:NM_006359.1 NM_006359 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 SLC9A6 10479 NM_001042537 /// NM_001177651 /// NM_006359 /// XM_006724726 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0048675 // axon extension // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0097484 // dendrite extension // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // traceable author statement /// 0055038 // recycling endosome membrane // inferred from direct assay 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation 203910_at NM_004815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004815.1 /DEF=Homo sapiens PTPL1-associated RhoGAP 1 (PARG1), mRNA. /FEA=mRNA /GEN=PARG1 /PROD=PTPL1-associated RhoGAP 1 /DB_XREF=gi:4758881 /UG=Hs.70983 PTPL1-associated RhoGAP 1 /FL=gb:U90920.1 gb:NM_004815.1 NM_004815 Rho GTPase activating protein 29 ARHGAP29 9411 NM_004815 /// XM_006711048 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203911_at NM_002885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002885.1 /DEF=Homo sapiens RAP1, GTPase activating protein 1 (RAP1GA1), mRNA. /FEA=mRNA /GEN=RAP1GA1 /PROD=RAP1, GTPase activating protein 1 /DB_XREF=gi:4506414 /UG=Hs.75151 RAP1, GTPase activating protein 1 /FL=gb:M64788.1 gb:NM_002885.1 NM_002885 RAP1 GTPase activating protein RAP1GAP 5909 NM_001145657 /// NM_001145658 /// NM_002885 /// XM_005245954 /// XM_005245955 /// XM_005245956 /// XM_006710804 /// XM_006710805 /// XM_006710806 /// XM_006710807 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0032318 // regulation of Ras GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003924 // GTPase activity // non-traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046582 // Rap GTPase activator activity // inferred from direct assay 203912_s_at NM_006730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006730.1 /DEF=Homo sapiens deoxyribonuclease I-like 1 (DNASE1L1), mRNA. /FEA=mRNA /GEN=DNASE1L1 /PROD=deoxyribonuclease I-like 1 /DB_XREF=gi:5803006 /UG=Hs.77091 deoxyribonuclease I-like 1 /FL=gb:U06846.1 gb:NM_006730.1 NM_006730 deoxyribonuclease I-like 1 DNASE1L1 1774 NM_001009932 /// NM_001009933 /// NM_001009934 /// NM_006730 /// XM_005277829 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation 203913_s_at AL574184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574184 /FEA=EST /DB_XREF=gi:12934146 /DB_XREF=est:AL574184 /CLONE=CS0DI039YJ22 (3 prime) /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:L76465.1 gb:NM_000860.1 AL574184 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 203914_x_at NM_000860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000860.1 /DEF=Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), mRNA. /FEA=mRNA /GEN=HPGD /PROD=hydroxyprostaglandin dehydrogenase 15-(NAD) /DB_XREF=gi:4504478 /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:L76465.1 gb:NM_000860.1 NM_000860 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 203915_at NM_002416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002416.1 /DEF=Homo sapiens monokine induced by gamma interferon (MIG), mRNA. /FEA=mRNA /GEN=MIG /PROD=monokine induced by gamma interferon /DB_XREF=gi:4505186 /UG=Hs.77367 monokine induced by gamma interferon /FL=gb:NM_002416.1 NM_002416 chemokine (C-X-C motif) ligand 9 CXCL9 4283 NM_002416 0006935 // chemotaxis // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 203916_at NM_003635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003635.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 2 (NDST2), mRNA. /FEA=mRNA /GEN=NDST2 /PROD=N-deacetylaseN-sulfotransferase (heparanglucosaminyl) 2 /DB_XREF=gi:4505352 /UG=Hs.78473 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 2 /FL=gb:U36601.1 gb:NM_003635.1 NM_003635 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 NDST2 8509 NM_003635 /// XM_005270255 /// XM_005270256 /// XM_006718046 0002002 // regulation of angiotensin levels in blood // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 203917_at NM_001338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001338.1 /DEF=Homo sapiens coxsackie virus and adenovirus receptor (CXADR), mRNA. /FEA=mRNA /GEN=CXADR /PROD=coxsackie virus and adenovirus receptor /DB_XREF=gi:4503172 /UG=Hs.79187 coxsackie virus and adenovirus receptor /FL=gb:BC003684.1 gb:U90716.1 gb:NM_001338.1 NM_001338 coxsackie virus and adenovirus receptor CXADR 1525 NM_001207063 /// NM_001207064 /// NM_001207065 /// NM_001207066 /// NM_001338 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008354 // germ cell migration // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from sequence or structural similarity /// 0046629 // gamma-delta T cell activation // inferred from sequence or structural similarity /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070633 // transepithelial transport // inferred from mutant phenotype /// 0086067 // AV node cell to bundle of His cell communication // inferred from sequence or structural similarity 0001669 // acrosomal vesicle // inferred from sequence or structural similarity /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016327 // apicolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0071253 // connexin binding // inferred from sequence or structural similarity 203918_at NM_002587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002587.1 /DEF=Homo sapiens protocadherin 1 (cadherin-like 1) (PCDH1), mRNA. /FEA=mRNA /GEN=PCDH1 /PROD=protocadherin 1 (cadherin-like 1) /DB_XREF=gi:4505630 /UG=Hs.79769 protocadherin 1 (cadherin-like 1) /FL=gb:L11370.1 gb:NM_002587.1 NM_002587 protocadherin 1 PCDH1 5097 NM_001278613 /// NM_001278615 /// NM_002587 /// NM_032420 /// XM_005268452 /// XM_005268453 /// XM_005268454 /// XM_005268455 /// XM_005268456 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 203919_at NM_003195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003195.1 /DEF=Homo sapiens transcription elongation factor A (SII), 2 (TCEA2), mRNA. /FEA=mRNA /GEN=TCEA2 /PROD=transcription elongation factor A (SII), 2 /DB_XREF=gi:4507384 /UG=Hs.80598 transcription elongation factor A (SII), 2 /FL=gb:D50495.1 gb:NM_003195.1 NM_003195 transcription elongation factor A (SII), 2 TCEA2 6919 NM_003195 /// NM_198723 /// XM_005260229 /// XM_006723873 /// XM_006723874 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0008023 // transcription elongation factor complex // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203920_at NM_005693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005693.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group H, member 3 (NR1H3), mRNA. /FEA=mRNA /GEN=NR1H3 /PROD=nuclear receptor subfamily 1, group H, member 3 /DB_XREF=gi:5031892 /UG=Hs.81336 nuclear receptor subfamily 1, group H, member 3 /FL=gb:NM_005693.1 gb:U22662.1 NM_005693 nuclear receptor subfamily 1, group H, member 3 NR1H3 10062 NM_001130101 /// NM_001130102 /// NM_001251934 /// NM_001251935 /// NM_005693 /// XM_005252705 /// XM_005252706 /// XM_005252707 /// XM_005252709 /// XM_005252710 /// XM_005252713 /// XM_005252715 /// XM_005252716 /// XM_005252718 /// XM_006718112 /// XM_006718113 /// XM_006718114 /// XM_006718115 /// XM_006718116 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from mutant phenotype /// 0010870 // positive regulation of receptor biosynthetic process // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010887 // negative regulation of cholesterol storage // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // traceable author statement /// 0043031 // negative regulation of macrophage activation // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0055092 // sterol homeostasis // inferred from sequence or structural similarity /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0090188 // negative regulation of pancreatic juice secretion // inferred from sequence or structural similarity /// 0090341 // negative regulation of secretion of lysosomal enzymes // inferred from sequence or structural similarity /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015485 // cholesterol binding // traceable author statement /// 0032810 // sterol response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203921_at NM_004267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004267.1 /DEF=Homo sapiens carbohydrate (chondroitin 6keratan) sulfotransferase 2 (CHST2), mRNA. /FEA=mRNA /GEN=CHST2 /PROD=carbohydrate (chondroitin 6keratan)sulfotransferase 2 /DB_XREF=gi:4757983 /UG=Hs.8786 carbohydrate (chondroitin 6keratan) sulfotransferase 2 /FL=gb:AB021124.1 gb:AB014679.1 gb:AB014680.1 gb:AF083066.1 gb:NM_004267.1 NM_004267 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 CHST2 9435 NM_004267 0005975 // carbohydrate metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // non-traceable author statement 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 203922_s_at AI308863 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI308863 /FEA=EST /DB_XREF=gi:4003734 /DB_XREF=est:qo78d02.x1 /CLONE=IMAGE:1914627 /UG=Hs.88974 cytochrome b-245, beta polypeptide (chronic granulomatous disease) /FL=gb:NM_000397.2 AI308863 cytochrome b-245, beta polypeptide CYBB 1536 NM_000397 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from mutant phenotype 203923_s_at NM_000397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000397.2 /DEF=Homo sapiens cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB), mRNA. /FEA=mRNA /GEN=CYBB /PROD=cytochrome b-245, beta polypeptide (chronicgranulomatous disease) /DB_XREF=gi:6996020 /UG=Hs.88974 cytochrome b-245, beta polypeptide (chronic granulomatous disease) /FL=gb:NM_000397.2 NM_000397 cytochrome b-245, beta polypeptide CYBB 1536 NM_000397 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from mutant phenotype 203924_at NM_000846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000846.1 /DEF=Homo sapiens glutathione S-transferase A2 (GSTA2), mRNA. /FEA=mRNA /GEN=GSTA2 /PROD=glutathione S-transferase A2 /DB_XREF=gi:4504170 /UG=Hs.89552 glutathione S-transferase A2 /FL=gb:BC002895.1 gb:M15872.1 gb:M21758.1 gb:M16594.1 gb:M14777.1 gb:M25627.1 gb:NM_000846.1 NM_000846 glutathione S-transferase alpha 1 GSTA1 2938 NM_145740 /// XM_005249034 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred by curator /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004364 // glutathione transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203925_at NM_002061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002061.1 /DEF=Homo sapiens glutamate-cysteine ligase, modifier subunit (GCLM), mRNA. /FEA=mRNA /GEN=GCLM /PROD=glutamate-cysteine ligase regulatory protein /DB_XREF=gi:4504010 /UG=Hs.89709 glutamate-cysteine ligase, modifier subunit /FL=gb:NM_002061.1 gb:L35546.1 NM_002061 glutamate-cysteine ligase, modifier subunit GCLM 2730 NM_002061 /// XM_005270754 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from electronic annotation /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035229 // positive regulation of glutamate-cysteine ligase activity // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0016874 // ligase activity // inferred from electronic annotation /// 0035226 // glutamate-cysteine ligase catalytic subunit binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203926_x_at NM_001687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001687.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit (ATP5D), mRNA. /FEA=mRNA /GEN=ATP5D /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, delta subunit /DB_XREF=gi:4502296 /UG=Hs.89761 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit /FL=gb:BC002389.1 gb:BC004426.1 gb:NM_001687.1 NM_001687 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit ATP5D 513 NM_001001975 /// NM_001687 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // non-traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046688 // response to copper ion // non-traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0043531 // ADP binding // non-traceable author statement /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 203927_at NM_004556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004556.1 /DEF=Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE), mRNA. /FEA=mRNA /GEN=NFKBIE /PROD=nuclear factor of kappa light polypeptide geneenhancer in B-cells inhibitor, epsilon /DB_XREF=gi:4758805 /UG=Hs.91640 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon /FL=gb:U91616.1 gb:NM_004556.1 NM_004556 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon NFKBIE 4794 NM_004556 0042942 // D-serine transport // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203928_x_at AI870749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI870749 /FEA=EST /DB_XREF=gi:5544717 /DB_XREF=est:wl76d10.x1 /CLONE=IMAGE:2430835 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1 AI870749 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203929_s_at AI056359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI056359 /FEA=EST /DB_XREF=gi:3330225 /DB_XREF=est:oy48b08.x1 /CLONE=IMAGE:1669047 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1 AI056359 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203930_s_at NM_016835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016835.1 /DEF=Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 1, mRNA. /FEA=mRNA /GEN=MAPT /PROD=microtubule-associated protein tau, isoform 1 /DB_XREF=gi:8400712 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1 NM_016835 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203931_s_at NM_002949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002949.1 /DEF=Homo sapiens mitochondrial ribosomal protein L12 (MRPL12), mRNA. /FEA=mRNA /GEN=MRPL12 /PROD=mitochondrial ribosomal protein L12 /DB_XREF=gi:4506672 /UG=Hs.109059 mitochondrial ribosomal protein L12 /FL=gb:BC002344.1 gb:U25041.1 gb:AF105278.1 gb:NM_002949.1 NM_002949 mitochondrial ribosomal protein L12 MRPL12 6182 NM_002949 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005310 // dicarboxylic acid transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203932_at NM_002118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002118.1 /DEF=Homo sapiens major histocompatibility complex, class II, DM beta (HLA-DMB), mRNA. /FEA=mRNA /GEN=HLA-DMB /PROD=major histocompatibility complex, class II, DMbeta /DB_XREF=gi:4504398 /UG=Hs.1162 major histocompatibility complex, class II, DM beta /FL=gb:NM_002118.1 gb:U15085.1 NM_002118 major histocompatibility complex, class II, DM beta HLA-DMB 3109 NM_002118 0002376 // immune system process // inferred from electronic annotation /// 0002399 // MHC class II protein complex assembly // inferred from mutant phenotype /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 2001190 // positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay 203933_at NM_014700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014700.1 /DEF=Homo sapiens KIAA0665 gene product (KIAA0665), mRNA. /FEA=mRNA /GEN=KIAA0665 /PROD=KIAA0665 gene product /DB_XREF=gi:7662233 /UG=Hs.119004 KIAA0665 gene product /FL=gb:AB014565.1 gb:NM_014700.1 NM_014700 RAB11 family interacting protein 3 (class II) RAB11FIP3 9727 NM_001142272 /// NM_014700 /// XM_005255713 /// XM_005255714 /// XM_005255715 /// XM_005255717 /// XM_005255718 /// XM_006720987 /// XM_006720988 /// XM_006725242 /// XM_006725243 /// XM_006725244 /// XM_006725245 /// XM_006725246 /// XM_006725247 /// XM_006725248 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // non-traceable author statement /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203934_at NM_002253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002253.1 /DEF=Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), mRNA. /FEA=mRNA /GEN=KDR /PROD=kinase insert domain receptor (a type IIIreceptor tyrosine kinase) /DB_XREF=gi:11321596 /UG=Hs.12337 kinase insert domain receptor (a type III receptor tyrosine kinase) /FL=gb:NM_002253.1 gb:AF035121.1 gb:AF063658.1 NM_002253 kinase insert domain receptor (a type III receptor tyrosine kinase) KDR 3791 NM_002253 0001525 // angiogenesis // traceable author statement /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003158 // endothelium development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement 203935_at NM_001105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001105.2 /DEF=Homo sapiens activin A receptor, type I (ACVR1), mRNA. /FEA=mRNA /GEN=ACVR1 /PROD=activin A type I receptor precursor /DB_XREF=gi:10862690 /UG=Hs.150402 activin A receptor, type I /FL=gb:NM_001105.2 gb:L02911.1 NM_001105 activin A receptor, type I ACVR1 90 NM_001105 /// NM_001111067 /// XM_005246939 /// XM_005246940 /// XM_006712825 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from mutant phenotype /// 0003183 // mitral valve morphogenesis // inferred from mutant phenotype /// 0003289 // atrial septum primum morphogenesis // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from mutant phenotype /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from mutant phenotype /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060923 // cardiac muscle cell fate commitment // inferred from mutant phenotype /// 0061445 // endocardial cushion cell fate commitment // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2000017 // positive regulation of determination of dorsal identity // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048179 // activin receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from reviewed computational analysis /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017046 // peptide hormone binding // non-traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from direct assay 203936_s_at NM_004994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004994.1 /DEF=Homo sapiens matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) (MMP9), mRNA. /FEA=mRNA /GEN=MMP9 /PROD=matrix metalloproteinase 9 preproprotein /DB_XREF=gi:4826835 /UG=Hs.151738 matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) /FL=gb:J05070.1 gb:NM_004994.1 NM_004994 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) MMP9 4318 NM_004994 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from mutant phenotype /// 1900122 // positive regulation of receptor binding // inferred from direct assay /// 2001258 // negative regulation of cation channel activity // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203937_s_at AW015313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW015313 /FEA=EST /DB_XREF=gi:5864070 /DB_XREF=est:UI-H-BI0-aap-e-09-0-UI.s1 /CLONE=IMAGE:2710001 /UG=Hs.153022 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD /FL=gb:NM_005679.1 gb:L39059.1 AW015313 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa TAF1C 9013 NM_001243156 /// NM_001243157 /// NM_001243158 /// NM_001243159 /// NM_001243160 /// NM_005679 /// NM_139353 /// XM_005256226 /// XM_005256227 /// XM_006721325 /// XM_006721326 /// XM_006721327 /// XM_006721328 /// XM_006721329 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203938_s_at NM_005679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005679.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD (TAF1C), mRNA. /FEA=mRNA /GEN=TAF1C /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase I, C, 110kD /DB_XREF=gi:5032144 /UG=Hs.153022 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD /FL=gb:NM_005679.1 gb:L39059.1 NM_005679 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa TAF1C 9013 NM_001243156 /// NM_001243157 /// NM_001243158 /// NM_001243159 /// NM_001243160 /// NM_005679 /// NM_139353 /// XM_005256226 /// XM_005256227 /// XM_006721325 /// XM_006721326 /// XM_006721327 /// XM_006721328 /// XM_006721329 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203939_at NM_002526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002526.1 /DEF=Homo sapiens 5 nucleotidase (CD73) (NT5), mRNA. /FEA=mRNA /GEN=NT5 /PROD=5 nucleotidase /DB_XREF=gi:4505466 /UG=Hs.153952 5 nucleotidase (CD73) /FL=gb:NM_002526.1 NM_002526 5'-nucleotidase, ecto (CD73) NT5E 4907 NM_001204813 /// NM_002526 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006196 // AMP catabolic process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0009166 // nucleotide catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046086 // adenosine biosynthetic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0008253 // 5'-nucleotidase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203940_s_at NM_014909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014909.1 /DEF=Homo sapiens KIAA1036 protein (KIAA1036), mRNA. /FEA=mRNA /GEN=KIAA1036 /PROD=KIAA1036 protein /DB_XREF=gi:7662453 /UG=Hs.155182 KIAA1036 protein /FL=gb:AB028959.1 gb:NM_014909.1 NM_014909 vasohibin 1 VASH1 22846 NM_014909 /// XM_006720080 0001525 // angiogenesis // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from genetic interaction /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from genetic interaction /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 1901491 // negative regulation of lymphangiogenesis // inferred from genetic interaction /// 2000772 // regulation of cellular senescence // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay 203941_at NM_018250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018250.1 /DEF=Homo sapiens hypothetical protein FLJ10871 (FLJ10871), mRNA. /FEA=mRNA /GEN=FLJ10871 /PROD=hypothetical protein FLJ10871 /DB_XREF=gi:8922725 /UG=Hs.15562 hypothetical protein FLJ10871 /FL=gb:NM_018250.1 NM_018250 integrator complex subunit 9 INTS9 55756 NM_001145159 /// NM_001172562 /// NM_018250 /// NR_026826 /// XM_005273568 /// XM_006716356 /// XM_006716357 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203942_s_at NM_017490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017490.1 /DEF=Homo sapiens ELKL motif kinase (EMK1), transcript variant 1, mRNA. /FEA=mRNA /GEN=EMK1 /PROD=ELKL motif kinase 1 isoform a /DB_XREF=gi:9845486 /UG=Hs.157199 ELKL motif kinase /FL=gb:NM_017490.1 NM_017490 MAP/microtubule affinity-regulating kinase 2 MARK2 2011 NM_001039469 /// NM_001163296 /// NM_001163297 /// NM_004954 /// NM_017490 /// XM_006718441 /// XM_006718442 /// XM_006718443 /// XM_006718444 /// XM_006718445 /// XM_006718446 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from mutant phenotype /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from mutant phenotype /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0045180 // basal cortex // inferred from electronic annotation /// 0097427 // microtubule bundle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity 203943_at NM_004798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004798.1 /DEF=Homo sapiens kinesin family member 3B (KIF3B), mRNA. /FEA=mRNA /GEN=KIF3B /PROD=kinesin family member 3B /DB_XREF=gi:4758645 /UG=Hs.168212 kinesin family member 3B /FL=gb:AB002357.1 gb:NM_004798.1 NM_004798 kinesin family member 3B KIF3B 9371 NM_004798 0007018 // microtubule-based movement // traceable author statement /// 0007052 // mitotic spindle organization // traceable author statement /// 0007100 // mitotic centrosome separation // traceable author statement /// 0007368 // determination of left/right symmetry // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0072383 // plus-end-directed vesicle transport along microtubule // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // non-traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005873 // plus-end kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // non-traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016939 // kinesin II complex // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008574 // plus-end-directed microtubule motor activity // traceable author statement /// 0017048 // Rho GTPase binding // inferred from physical interaction 203944_x_at NM_007049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007049.1 /DEF=Homo sapiens butyrophilin, subfamily 2, member A1 (BTN2A1), mRNA. /FEA=mRNA /GEN=BTN2A1 /PROD=butyrophilin, subfamily 2, member A1 /DB_XREF=gi:5921460 /UG=Hs.169963 butyrophilin, subfamily 2, member A1 /FL=gb:U90543.1 gb:NM_007049.1 NM_007049 butyrophilin, subfamily 2, member A1 BTN2A1 11120 NM_001197233 /// NM_001197234 /// NM_007049 /// NM_078476 0006629 // lipid metabolic process // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203945_at NM_001172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001172.2 /DEF=Homo sapiens arginase, type II (ARG2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ARG2 /PROD=arginase, type II precursor /DB_XREF=gi:10947110 /UG=Hs.172851 arginase, type II /FL=gb:NM_001172.2 gb:BC001350.1 gb:D86724.1 gb:U75667.1 gb:U82256.1 NM_001172 arginase 2 ARG2 384 NM_001172 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0004053 // arginase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203946_s_at U75667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U75667.1 /DEF=Human arginase II mRNA, complete cds. /FEA=mRNA /PROD=arginase II /DB_XREF=gi:1763757 /UG=Hs.172851 arginase, type II /FL=gb:NM_001172.2 gb:BC001350.1 gb:D86724.1 gb:U75667.1 gb:U82256.1 U75667 arginase 2 ARG2 384 NM_001172 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0004053 // arginase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203947_at NM_001326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001326.1 /DEF=Homo sapiens cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kD (CSTF3), mRNA. /FEA=mRNA /GEN=CSTF3 /PROD=cleavage stimulation factor subunit 3 /DB_XREF=gi:4557494 /UG=Hs.180034 cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kD /FL=gb:NM_001326.1 gb:U15782.1 NM_001326 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa CSTF3 1479 NM_001033505 /// NM_001033506 /// NM_001326 /// XM_006718154 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203948_s_at J02694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02694.1 /DEF=Human myeloperoxidase mRNA, complete cds. /FEA=mRNA /GEN=MPO /PROD=myeloperoxidase /DB_XREF=gi:189039 /UG=Hs.1817 myeloperoxidase /FL=gb:M19507.1 gb:J02694.1 gb:NM_000250.1 J02694 myeloperoxidase MPO 4353 NM_000250 0001878 // response to yeast // inferred from electronic annotation /// 0002149 // hypochlorous acid biosynthetic process // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0030141 // secretory granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0004601 // peroxidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203949_at NM_000250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000250.1 /DEF=Homo sapiens myeloperoxidase (MPO), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MPO /PROD=myeloperoxidase /DB_XREF=gi:4557758 /UG=Hs.1817 myeloperoxidase /FL=gb:M19507.1 gb:J02694.1 gb:NM_000250.1 NM_000250 myeloperoxidase MPO 4353 NM_000250 0001878 // response to yeast // inferred from electronic annotation /// 0002149 // hypochlorous acid biosynthetic process // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0030141 // secretory granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0004601 // peroxidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203950_s_at NM_001286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001286.1 /DEF=Homo sapiens chloride channel 6 (CLCN6), transcript variant ClC-6a, mRNA. /FEA=mRNA /GEN=CLCN6 /PROD=chloride channel 6, isoform ClC-6a /DB_XREF=gi:4502872 /UG=Hs.211614 chloride channel 6 /FL=gb:NM_001286.1 NM_001286 chloride channel, voltage-sensitive 6 CLCN6 1185 NM_001256959 /// NM_001286 /// NM_021735 /// NM_021736 /// NM_021737 /// NR_046428 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0006884 // cell volume homeostasis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 203951_at NM_001299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001299.1 /DEF=Homo sapiens calponin 1, basic, smooth muscle (CNN1), mRNA. /FEA=mRNA /GEN=CNN1 /PROD=calponin 1, basic, smooth muscle /DB_XREF=gi:4502920 /UG=Hs.21223 calponin 1, basic, smooth muscle /FL=gb:U37019.1 gb:D17408.1 gb:NM_001299.1 NM_001299 calponin 1, basic, smooth muscle CNN1 1264 NM_001299 /// XM_005259741 /// XM_006722648 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0031032 // actomyosin structure organization // inferred from electronic annotation 0005856 // cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 203952_at NM_007348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007348.1 /DEF=Homo sapiens activating transcription factor 6 (ATF6), mRNA. /FEA=mRNA /GEN=ATF6 /PROD=activating transcription factor 6 /DB_XREF=gi:6671584 /UG=Hs.247433 activating transcription factor 6 /FL=gb:AF005887.1 gb:AB015856.1 gb:NM_007348.1 NM_007348 activating transcription factor 6 ATF6 22926 NM_007348 /// XM_006711224 /// XM_006711225 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006990 // positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203953_s_at BE791251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE791251 /FEA=EST /DB_XREF=gi:10212449 /DB_XREF=est:601583966F1 /CLONE=IMAGE:3938249 /UG=Hs.25640 claudin 3 /FL=gb:AB000714.1 gb:NM_001306.1 BE791251 claudin 3 CLDN3 1365 NM_001306 0001666 // response to hypoxia // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203954_x_at NM_001306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001306.1 /DEF=Homo sapiens claudin 3 (CLDN3), mRNA. /FEA=mRNA /GEN=CLDN3 /PROD=claudin 3 /DB_XREF=gi:4502874 /UG=Hs.25640 claudin 3 /FL=gb:AB000714.1 gb:NM_001306.1 NM_001306 claudin 3 CLDN3 1365 NM_001306 0001666 // response to hypoxia // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203955_at NM_014811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014811.1 /DEF=Homo sapiens KIAA0649 gene product (KIAA0649), mRNA. /FEA=mRNA /GEN=KIAA0649 /PROD=KIAA0649 gene product /DB_XREF=gi:7662223 /UG=Hs.26163 KIAA0649 gene product /FL=gb:AB014549.1 gb:NM_014811.1 NM_014811 protein phosphatase 1, regulatory subunit 26 PPP1R26 9858 NM_014811 /// XM_005263411 /// XM_005263412 /// XM_006717340 /// XM_006717341 /// XM_006717342 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 203956_at NM_014941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014941.1 /DEF=Homo sapiens KIAA0852 protein (KIAA0852), mRNA. /FEA=mRNA /GEN=KIAA0852 /PROD=KIAA0852 protein /DB_XREF=gi:7662339 /UG=Hs.35276 KIAA0852 protein /FL=gb:AB020659.1 gb:NM_014941.1 NM_014941 MORC family CW-type zinc finger 2 MORC2 22880 NM_014941 /// XM_005261391 /// XM_005261392 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203957_at NM_001952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001952.2 /DEF=Homo sapiens E2F transcription factor 6 (E2F6), mRNA. /FEA=mRNA /GEN=E2F6 /PROD=E2F transcription factor 6 /DB_XREF=gi:12669917 /UG=Hs.42287 E2F transcription factor 6 /FL=gb:NM_001952.2 gb:AF059292.1 NM_001952 E2F transcription factor 6 E2F6 1876 NM_001278275 /// NM_001278276 /// NM_001278277 /// NM_001278278 /// NM_198256 /// NM_198257 /// NM_198258 /// NM_198325 /// NM_212540 /// NR_103490 /// XM_005246154 /// XM_005246155 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement 203958_s_at AI557467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI557467 /FEA=EST /DB_XREF=gi:4489830 /DB_XREF=est:PT2.1_7_F07.r /UG=Hs.4236 KIAA0478 gene product /FL=gb:AB007947.1 gb:NM_014870.1 AI557467 zinc finger and BTB domain containing 40 ZBTB40 9923 NM_001083621 /// NM_014870 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0030282 // bone mineralization // non-traceable author statement 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203959_s_at NM_014870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014870.1 /DEF=Homo sapiens KIAA0478 gene product (KIAA0478), mRNA. /FEA=mRNA /GEN=KIAA0478 /PROD=KIAA0478 gene product /DB_XREF=gi:7662153 /UG=Hs.4236 KIAA0478 gene product /FL=gb:AB007947.1 gb:NM_014870.1 NM_014870 zinc finger and BTB domain containing 40 ZBTB40 9923 NM_001083621 /// NM_014870 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0030282 // bone mineralization // non-traceable author statement 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203960_s_at NM_016126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016126.1 /DEF=Homo sapiens HSPCO34 protein (LOC51668), mRNA. /FEA=mRNA /GEN=LOC51668 /PROD=HSPCO34 protein /DB_XREF=gi:7706382 /UG=Hs.46967 HSPCO34 protein /FL=gb:BC005245.1 gb:AF100747.1 gb:NM_016126.1 NM_016126 heat shock protein family B (small), member 11 HSPB11 51668 NM_016126 /// XM_005270942 /// XM_005270943 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005929 // cilium // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 203961_at AL157398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157398 /DEF=Human DNA sequence from clone RP11-56H7 on chromosome 10. Contains ESTs, STSs and GSSs. Contains the gene for the nebulette protein (NEBL, actin-binding Z-disc protein) /FEA=mRNA_1 /DB_XREF=gi:10045326 /UG=Hs.5025 nebulette /FL=gb:NM_006393.1 AL157398 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 203962_s_at NM_006393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006393.1 /DEF=Homo sapiens nebulette (NEBL), mRNA. /FEA=mRNA /GEN=NEBL /PROD=nebulette /DB_XREF=gi:5453757 /UG=Hs.5025 nebulette /FL=gb:NM_006393.1 NM_006393 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 203963_at NM_001218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001218.2 /DEF=Homo sapiens carbonic anhydrase XII (CA12), mRNA. /FEA=mRNA /GEN=CA12 /PROD=carbonic anhydrase XII precursor /DB_XREF=gi:9951924 /UG=Hs.5338 carbonic anhydrase XII /FL=gb:AF037335.1 gb:AF051882.1 gb:NM_001218.2 NM_001218 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203964_at NM_004688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004688.1 /DEF=Homo sapiens N-myc (and STAT) interactor (NMI), mRNA. /FEA=mRNA /GEN=NMI /PROD=N-myc and STAT interactor /DB_XREF=gi:4758813 /UG=Hs.54483 N-myc (and STAT) interactor /FL=gb:BC001268.1 gb:U32849.1 gb:NM_004688.1 NM_004688 N-myc (and STAT) interactor NMI 9111 NM_004688 /// XM_005246941 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203965_at NM_006676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006676.1 /DEF=Homo sapiens ubiquitin specific protease 20 (USP20), mRNA. /FEA=mRNA /GEN=USP20 /PROD=ubiquitin specific protease 20 /DB_XREF=gi:5730107 /UG=Hs.5452 ubiquitin specific protease 20 /FL=gb:AB023220.1 gb:NM_006676.1 NM_006676 ubiquitin specific peptidase 20 USP20 10868 NM_001008563 /// NM_001110303 /// NM_006676 /// XM_005251665 /// XM_005251666 /// XM_006716938 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203966_s_at NM_021003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021003.1 /DEF=Homo sapiens protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform (PPM1A), mRNA. /FEA=mRNA /GEN=PPM1A /PROD=protein phosphatase 1A (formerly 2C),magnesium-dependent, alpha isoform /DB_XREF=gi:10337594 /UG=Hs.57764 protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform /FL=gb:NM_021003.1 NM_021003 protein phosphatase, Mg2+/Mn2+ dependent, 1A PPM1A 5494 NM_021003 /// NM_177951 /// NM_177952 /// XM_005267777 /// XM_005267778 /// XM_005267779 /// XM_005267780 /// XM_005267781 /// XM_006720179 /// XM_006720180 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from physical interaction 203967_at U77949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U77949.1 /DEF=Human Cdc6-related protein (HsCDC6) mRNA, complete cds. /FEA=mRNA /GEN=HsCDC6 /PROD=Cdc6-related protein /DB_XREF=gi:1684902 /UG=Hs.69563 CDC6 (cell division cycle 6, S. cerevisiae) homolog /FL=gb:U77949.1 gb:AF022109.1 gb:NM_001254.1 U77949 cell division cycle 6 CDC6 990 NM_001254 0000076 // DNA replication checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051984 // positive regulation of chromosome segregation // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 203968_s_at NM_001254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001254.1 /DEF=Homo sapiens CDC6 (cell division cycle 6, S. cerevisiae) homolog (CDC6), mRNA. /FEA=mRNA /GEN=CDC6 /PROD=CDC6 (cell division cycle 6, S. cerevisiae)homolog /DB_XREF=gi:4502702 /UG=Hs.69563 CDC6 (cell division cycle 6, S. cerevisiae) homolog /FL=gb:U77949.1 gb:AF022109.1 gb:NM_001254.1 NM_001254 cell division cycle 6 CDC6 990 NM_001254 0000076 // DNA replication checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051984 // positive regulation of chromosome segregation // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 203969_at AU157140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157140 /FEA=EST /DB_XREF=gi:11018661 /DB_XREF=est:AU157140 /CLONE=PLACE1006288 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1 AU157140 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203970_s_at NM_003630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003630.1 /DEF=Homo sapiens peroxisomal biogenesis factor 3 (PEX3), mRNA. /FEA=mRNA /GEN=PEX3 /PROD=peroxisomal biogenesis factor 3 /DB_XREF=gi:4505726 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1 NM_003630 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203971_at NM_001859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001859.1 /DEF=Homo sapiens solute carrier family 31 (copper transporters), member 1 (SLC31A1), mRNA. /FEA=mRNA /GEN=SLC31A1 /PROD=solute carrier family 31 (copper transporters),member 1 /DB_XREF=gi:4507014 /UG=Hs.73614 solute carrier family 31 (copper transporters), member 1 /FL=gb:U83460.1 gb:NM_001859.1 NM_001859 solute carrier family 31 (copper transporter), member 1 SLC31A1 1317 NM_001859 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005375 // copper ion transmembrane transporter activity // inferred from electronic annotation 203972_s_at AB035307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035307.1 /DEF=Homo sapiens mRNA for Pex3p, complete cds. /FEA=mRNA /GEN=PEX3 /PROD=Pex3p /DB_XREF=gi:8926848 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1 AB035307 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203973_s_at NM_005195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005195.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), delta (CEBPD), mRNA. /FEA=mRNA /GEN=CEBPD /PROD=CCAATenhancer binding protein (CEBP), delta /DB_XREF=gi:4885130 /UG=Hs.76722 CCAATenhancer binding protein (CEBP), delta /FL=gb:M83667.1 gb:NM_005195.1 NM_005195 CCAAT/enhancer binding protein (C/EBP), delta CEBPD 1052 NM_005195 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203974_at NM_012080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012080.1 /DEF=Homo sapiens DNA segment, numerous copies, expressed probes (GS1 gene) (DXF68S1E), mRNA. /FEA=mRNA /GEN=DXF68S1E /PROD=DNA segment, numerous copies, expressed probes(GS1 gene) /DB_XREF=gi:6912345 /UG=Hs.78991 DNA segment, numerous copies, expressed probes (GS1 gene) /FL=gb:M86934.1 gb:NM_012080.1 NM_012080 haloacid dehalogenase-like hydrolase domain containing 1 HDHD1 8226 NM_001135565 /// NM_001178135 /// NM_001178136 /// NM_012080 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203975_s_at BF000239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF000239 /FEA=EST /DB_XREF=gi:10700514 /DB_XREF=est:7h24b08.x1 /CLONE=IMAGE:3316887 /UG=Hs.79018 chromatin assembly factor 1, subunit A (p150) /FL=gb:NM_005483.1 gb:U20979.1 BF000239 chromatin assembly factor 1, subunit A (p150) CHAF1A 10036 NM_005483 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement /// 0070087 // chromo shadow domain binding // inferred from physical interaction 203976_s_at NM_005483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005483.1 /DEF=Homo sapiens chromatin assembly factor 1, subunit A (p150) (CHAF1A), mRNA. /FEA=mRNA /GEN=CHAF1A /PROD=chromatin assembly factor 1, subunit A (p150) /DB_XREF=gi:4885106 /UG=Hs.79018 chromatin assembly factor 1, subunit A (p150) /FL=gb:NM_005483.1 gb:U20979.1 NM_005483 chromatin assembly factor 1, subunit A (p150) CHAF1A 10036 NM_005483 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement /// 0070087 // chromo shadow domain binding // inferred from physical interaction 203977_at NM_000116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000116.1 /DEF=Homo sapiens tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) (TAZ), mRNA. /FEA=mRNA /GEN=TAZ /PROD=tafazzin /DB_XREF=gi:4507370 /UG=Hs.79021 tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) /FL=gb:NM_000116.1 NM_000116 tafazzin TAZ 6901 NM_000116 /// NM_181311 /// NM_181312 /// NM_181313 /// NM_181314 /// NR_024048 /// XM_006724836 /// XM_006724837 /// XM_006724838 /// XM_006724839 /// XM_006724840 /// XM_006724841 /// XM_006724842 0006644 // phospholipid metabolic process // traceable author statement /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042407 // cristae formation // inferred from mutant phenotype /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from direct assay 203978_at NM_002484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002484.1 /DEF=Homo sapiens nucleotide binding protein 1 (E.coli MinD like) (NUBP1), mRNA. /FEA=mRNA /GEN=NUBP1 /PROD=nucleotide binding protein 1 (E.coli MinD like) /DB_XREF=gi:4505336 /UG=Hs.81469 nucleotide binding protein 1 (E.coli MinD like) /FL=gb:NM_002484.1 gb:U01833.1 NM_002484 nucleotide binding protein 1 NUBP1 4682 NM_001278506 /// NM_002484 /// XM_006720886 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0010826 // negative regulation of centrosome duplication // inferred from electronic annotation /// 0016049 // cell growth // inferred from mutant phenotype /// 0016226 // iron-sulfur cluster assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051642 // centrosome localization // inferred from electronic annotation /// 0072697 // protein localization to cell cortex // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from direct assay /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 203979_at NM_000784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000784.1 /DEF=Homo sapiens cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 (CYP27A1), mRNA. /FEA=mRNA /GEN=CYP27A1 /PROD=cytochrome P450, subfamily XXVIIA (steroid27-hydroxylase, cerebrotendinous xanthomatosis),polypeptide 1 /DB_XREF=gi:4503210 /UG=Hs.82568 cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 /FL=gb:M62401.1 gb:NM_000784.1 NM_000784 cytochrome P450, family 27, subfamily A, polypeptide 1 CYP27A1 1593 NM_000784 0006699 // bile acid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0036378 // calcitriol biosynthetic process from calciol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from electronic annotation /// 0031073 // cholesterol 26-hydroxylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047749 // cholestanetriol 26-monooxygenase activity // inferred from electronic annotation 203980_at NM_001442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001442.1 /DEF=Homo sapiens fatty acid binding protein 4, adipocyte (FABP4), mRNA. /FEA=mRNA /GEN=FABP4 /PROD=fatty acid binding protein 4, adipocyte /DB_XREF=gi:4557578 /UG=Hs.83213 fatty acid binding protein 4, adipocyte /FL=gb:BC003672.1 gb:J02874.1 gb:NM_001442.1 NM_001442 fatty acid binding protein 4, adipocyte FABP4 2167 NM_001442 0001816 // cytokine production // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005811 // lipid particle // traceable author statement 0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 203981_s_at AL574660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574660 /FEA=EST /DB_XREF=gi:12935072 /DB_XREF=est:AL574660 /CLONE=CS0DI065YF14 (3 prime) /UG=Hs.94395 ATP-binding cassette, sub-family D (ALD), member 4 /FL=gb:AF009746.1 gb:NM_005050.1 AL574660 ATP-binding cassette, sub-family D (ALD), member 4 ABCD4 5826 NM_005050 /// NM_020324 /// NM_020325 /// NM_020326 /// NR_003256 /// XM_005267936 /// XM_005267938 /// XM_005267939 /// XM_005267940 /// XM_005267941 /// XM_005267942 /// XM_005267946 /// XM_005267949 /// XM_005267951 /// XM_005267952 /// XM_005267953 /// XM_005267954 /// XM_006720223 /// XR_245710 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // non-traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement 203982_s_at NM_005050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005050.1 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCD4 /PROD=ATP-binding cassette, sub-family D, member 4,isoform 1 /DB_XREF=gi:4826957 /UG=Hs.94395 ATP-binding cassette, sub-family D (ALD), member 4 /FL=gb:AF009746.1 gb:NM_005050.1 NM_005050 ATP-binding cassette, sub-family D (ALD), member 4 ABCD4 5826 NM_005050 /// NM_020324 /// NM_020325 /// NM_020326 /// NR_003256 /// XM_005267936 /// XM_005267938 /// XM_005267939 /// XM_005267940 /// XM_005267941 /// XM_005267942 /// XM_005267946 /// XM_005267949 /// XM_005267951 /// XM_005267952 /// XM_005267953 /// XM_005267954 /// XM_006720223 /// XR_245710 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // non-traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement 203983_at NM_005999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005999.1 /DEF=Homo sapiens translin-associated factor X (TSNAX), mRNA. /FEA=mRNA /GEN=TSNAX /PROD=translin-associated factor X /DB_XREF=gi:5174730 /UG=Hs.96247 translin-associated factor X /FL=gb:NM_005999.1 NM_005999 translin-associated factor X TSNAX 7257 NM_005999 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from mutant phenotype /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from genetic interaction /// 0031929 // TOR signaling // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0090128 // regulation of synapse maturation // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // traceable author statement /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203984_s_at U60521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U60521.1 /DEF=Human protease proMch6 (Mch6) mRNA, complete cds. /FEA=mRNA /GEN=Mch6 /PROD=proMch6 /DB_XREF=gi:1532150 /UG=Hs.100641 caspase 9, apoptosis-related cysteine protease /FL=gb:BC002452.1 gb:U56390.1 gb:U60521.1 gb:NM_001229.1 U60521 caspase 9, apoptosis-related cysteine peptidase CASP9 842 NM_001229 /// NM_001278054 /// NM_032996 /// NR_102732 /// NR_102733 /// XM_005246014 /// XR_426635 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030220 // platelet formation // traceable author statement /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay 203985_at NM_012256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012256.1 /DEF=Homo sapiens zinc finger protein 212 (ZNF212), mRNA. /FEA=mRNA /GEN=ZNF212 /PROD=zinc finger protein 212 /DB_XREF=gi:6912749 /UG=Hs.108139 zinc finger protein 212 /FL=gb:U38864.1 gb:NM_012256.1 NM_012256 zinc finger protein 212 ZNF212 7988 NM_012256 /// XM_005250055 /// XM_006716133 /// XM_006716134 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203986_at NM_003943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003943.1 /DEF=Homo sapiens genethonin 1 (GENX-3414), mRNA. /FEA=mRNA /GEN=GENX-3414 /PROD=genethonin 1 /DB_XREF=gi:4503976 /UG=Hs.109590 genethonin 1 /FL=gb:AF062534.1 gb:NM_003943.1 NM_003943 family with sequence similarity 47, member E /// FAM47E-STBD1 readthrough /// starch binding domain 1 FAM47E /// FAM47E-STBD1 /// STBD1 8987 /// 100129583 /// 100631383 NM_001136570 /// NM_001242936 /// NM_001242939 /// NM_003943 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 2001070 // starch binding // inferred from electronic annotation 203987_at NM_003506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003506.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 6 (FZD6), mRNA. /FEA=mRNA /GEN=FZD6 /PROD=frizzled 6 /DB_XREF=gi:4503830 /UG=Hs.114218 frizzled (Drosophila) homolog 6 /FL=gb:AB012911.1 gb:NM_003506.1 gb:AF072873.1 NM_003506 frizzled class receptor 6 FZD6 8323 NM_001164615 /// NM_001164616 /// NM_003506 /// XR_428385 0001525 // angiogenesis // not recorded /// 0001736 // establishment of planar polarity // not recorded /// 0001843 // neural tube closure // not recorded /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0008406 // gonad development // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0033278 // cell proliferation in midbrain // not recorded /// 0035567 // non-canonical Wnt signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // not recorded /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // not recorded /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // inferred from direct assay 203988_s_at NM_004480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004480.1 /DEF=Homo sapiens fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (FUT8), mRNA. /FEA=mRNA /GEN=FUT8 /PROD=fucosyltransferase 8 (alpha (1,6)fucosyltransferase) /DB_XREF=gi:4758407 /UG=Hs.118722 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) /FL=gb:D89289.1 gb:NM_004480.1 NM_004480 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) FUT8 2530 NM_004480 /// NM_178154 /// NM_178155 /// NM_178156 /// NM_178157 /// NR_038167 /// NR_038170 /// XM_006720096 /// XM_006720097 0001701 // in utero embryonic development // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0006491 // N-glycan processing // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0033578 // protein glycosylation in Golgi // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036071 // N-glycan fucosylation // inferred from direct assay /// 0036071 // N-glycan fucosylation // inferred from electronic annotation /// 0036071 // N-glycan fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement /// 0043112 // receptor metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046368 // GDP-L-fucose metabolic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008424 // glycoprotein 6-alpha-L-fucosyltransferase activity // inferred from direct assay /// 0008424 // glycoprotein 6-alpha-L-fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046921 // alpha-(1->6)-fucosyltransferase activity // inferred from electronic annotation 203989_x_at NM_001992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001992.2 /DEF=Homo sapiens coagulation factor II (thrombin) receptor (F2R), mRNA. /FEA=mRNA /GEN=F2R /PROD=coagulation factor II receptor precursor /DB_XREF=gi:6031164 /UG=Hs.128087 coagulation factor II (thrombin) receptor /FL=gb:BC002464.1 gb:M62424.1 gb:NM_001992.2 NM_001992 coagulation factor II (thrombin) receptor F2R 2149 NM_001992 0000186 // activation of MAPKK activity // inferred from sequence or structural similarity /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // inferred from direct assay /// 0003105 // negative regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007260 // tyrosine phosphorylation of STAT protein // inferred from direct assay /// 0007262 // STAT protein import into nucleus // inferred from direct assay /// 0007529 // establishment of synaptic specificity at neuromuscular junction // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from direct assay /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016265 // death // inferred from electronic annotation /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032651 // regulation of interleukin-1 beta production // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0048873 // homeostasis of number of cells within a tissue // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from sequence or structural similarity /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity /// 0060155 // platelet dense granule organization // inferred by curator /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation /// 1900134 // negative regulation of renin secretion into blood stream // inferred from sequence or structural similarity /// 2000484 // positive regulation of interleukin-8 secretion // inferred from direct assay /// 2000778 // positive regulation of interleukin-6 secretion // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0001965 // G-protein alpha-subunit binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // inferred from direct assay /// 0031681 // G-protein beta-subunit binding // inferred from sequence or structural similarity 203990_s_at AI140752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI140752 /FEA=EST /DB_XREF=gi:3648209 /DB_XREF=est:qa50e08.x1 /CLONE=IMAGE:1690214 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1 AI140752 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203991_s_at NM_021140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021140.1 /DEF=Homo sapiens ubiquitously transcribed tetratricopeptide repeat gene, X chromosome (UTX), mRNA. /FEA=mRNA /GEN=UTX /PROD=ubiquitously transcribed tetratricopeptiderepeat gene, X chromosome /DB_XREF=gi:10863942 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1 NM_021140 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203992_s_at AF000992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000992.1 /DEF=Homo sapiens ubiquitous TPR motif, X isoform (UTX) mRNA, alternative transcript 1, complete cds. /FEA=mRNA /GEN=UTX /PROD=ubiquitous TPR motif, X isoform /DB_XREF=gi:2580569 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1 AF000992 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203993_x_at U84569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U84569.1 /DEF=Human YF5 mRNA, complete cds. /FEA=mRNA /PROD=YF5 /DB_XREF=gi:1835524 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1 U84569 /// chromosome 21 open reading frame 2 AP001062.7 /// C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203994_s_at U84569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84569.1 /DEF=Human YF5 mRNA, complete cds. /FEA=mRNA /PROD=YF5 /DB_XREF=gi:1835524 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1 U84569 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203995_at NM_004928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004928.1 /DEF=Homo sapiens chromosome 21 open reading frame 2 (C21ORF2), mRNA. /FEA=mRNA /GEN=C21ORF2 /PROD=chromosome 21 open reading frame 2 /DB_XREF=gi:4826650 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1 NM_004928 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203996_s_at NM_004928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004928.1 /DEF=Homo sapiens chromosome 21 open reading frame 2 (C21ORF2), mRNA. /FEA=mRNA /GEN=C21ORF2 /PROD=chromosome 21 open reading frame 2 /DB_XREF=gi:4826650 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1 NM_004928 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203997_at NM_002829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002829.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), mRNA. /FEA=mRNA /GEN=PTPN3 /PROD=protein tyrosine phosphatase, non-receptor type3 /DB_XREF=gi:4506292 /UG=Hs.153932 protein tyrosine phosphatase, non-receptor type 3 /FL=gb:M64572.1 gb:NM_002829.1 NM_002829 protein tyrosine phosphatase, non-receptor type 3 PTPN3 5774 NM_001145368 /// NM_001145369 /// NM_001145370 /// NM_001145371 /// NM_001145372 /// NM_002829 /// NR_026918 /// XM_006717197 /// XM_006717198 /// XM_006717199 /// XM_006717200 /// XM_006717201 /// XM_006717202 /// XM_006717203 /// XM_006717204 /// XM_006717205 /// XM_006717206 /// XM_006717207 0006470 // protein dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0001784 // phosphotyrosine binding // inferred from physical interaction /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 203998_s_at AV723167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV723167 /FEA=EST /DB_XREF=gi:10826344 /DB_XREF=est:AV723167 /CLONE=HTBAOF10 /UG=Hs.154679 synaptotagmin I /FL=gb:M55047.1 gb:NM_005639.1 AV723167 synaptotagmin I SYT1 6857 NM_001135805 /// NM_001135806 /// NM_001291901 /// NM_005639 /// XM_005269113 /// XM_006719576 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from electronic annotation /// 0051260 // protein homooligomerization // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // traceable author statement /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 203999_at AV731490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV731490 /FEA=EST /DB_XREF=gi:10840911 /DB_XREF=est:AV731490 /CLONE=HTFAZD04 /UG=Hs.154679 synaptotagmin I /FL=gb:M55047.1 gb:NM_005639.1 AV731490 synaptotagmin I SYT1 6857 NM_001135805 /// NM_001135806 /// NM_001291901 /// NM_005639 /// XM_005269113 /// XM_006719576 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from electronic annotation /// 0051260 // protein homooligomerization // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // traceable author statement /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 204000_at NM_016194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016194.1 /DEF=Homo sapiens hypothetical protein (DKFZp586O1922), mRNA. /FEA=mRNA /GEN=DKFZp586O1922 /PROD=hypothetical protein /DB_XREF=gi:7705366 /UG=Hs.155090 hypothetical protein /FL=gb:AL117471.1 gb:NM_016194.1 NM_016194 guanine nucleotide binding protein (G protein), beta 5 GNB5 10681 NM_006578 /// NM_016194 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031682 // G-protein gamma-subunit binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 204001_at NM_003084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003084.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 3, 50kD (SNAPC3), mRNA. /FEA=mRNA /GEN=SNAPC3 /PROD=small nuclear RNA activating complex,polypeptide 3, 50kD /DB_XREF=gi:4507104 /UG=Hs.164915 small nuclear RNA activating complex, polypeptide 3, 50kD /FL=gb:U66413.1 gb:NM_003084.1 NM_003084 small nuclear RNA activating complex, polypeptide 3, 50kDa SNAPC3 6619 NM_001039697 /// NM_003084 /// XR_428427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 204002_s_at NM_022307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022307.1 /DEF=Homo sapiens islet cell autoantigen 1 (69kD) (ICA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ICA1 /PROD=islet cell autoantigen 1, isoform 1 /DB_XREF=gi:12545394 /UG=Hs.167927 islet cell autoantigen 1 (69kD) /FL=gb:NM_022307.1 gb:U26591.1 NM_022307 islet cell autoantigen 1, 69kDa ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 204003_s_at NM_007342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007342.1 /DEF=Homo sapiens nucleoporin-like protein 1 (NLP_1), mRNA. /FEA=mRNA /GEN=NLP_1 /PROD=nucleoporin-like protein 1 /DB_XREF=gi:6679073 /UG=Hs.168352 nucleoporin-like protein 1 /FL=gb:U97198.1 gb:NM_007342.1 NM_007342 nucleoporin like 2 NUPL2 11097 NM_007342 /// XM_005249592 /// XM_005249593 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005049 // nuclear export signal receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204004_at AI336206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI336206 /FEA=EST /DB_XREF=gi:4073133 /DB_XREF=est:qt44e12.x1 /CLONE=IMAGE:1950862 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator /FL=gb:U63809.1 gb:NM_002583.1 AI336206 PRKC, apoptosis, WT1, regulator PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 204005_s_at NM_002583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002583.1 /DEF=Homo sapiens PRKC, apoptosis, WT1, regulator (PAWR), mRNA. /FEA=mRNA /GEN=PAWR /PROD=apoptosis response protein /DB_XREF=gi:4505612 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator /FL=gb:U63809.1 gb:NM_002583.1 NM_002583 PRKC, apoptosis, WT1, regulator PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 204006_s_at NM_000570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000570.1 /DEF=Homo sapiens Fc fragment of IgG, low affinity IIIb, receptor for (CD16) (FCGR3B), mRNA. /FEA=mRNA /GEN=FCGR3B /PROD=Fc fragment of IgG, low affinity IIIb, receptorfor (CD16) /DB_XREF=gi:10835138 /UG=Hs.176663 Fc fragment of IgG, low affinity IIIb, receptor for (CD16) /FL=gb:NM_000570.1 gb:J04162.1 gb:M24854.1 gb:AB025256.1 NM_000570 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) /// Fc fragment of IgG, low affinity IIIb, receptor (CD16b) FCGR3A /// FCGR3B 2214 /// 2215 NM_000569 /// NM_000570 /// NM_001127592 /// NM_001127593 /// NM_001127595 /// NM_001127596 /// NM_001244753 /// NM_001271035 /// NM_001271036 /// NM_001271037 /// XM_006710063 /// XM_006710064 /// XM_006711211 0006955 // immune response // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 204007_at J04162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04162.1 /DEF=Human leukocyte IgG receptor (Fc-gamma-R) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183036 /UG=Hs.176663 Fc fragment of IgG, low affinity IIIb, receptor for (CD16) /FL=gb:NM_000570.1 gb:J04162.1 gb:M24854.1 gb:AB025256.1 J04162 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) FCGR3B 2215 NM_000570 /// NM_001244753 /// NM_001271035 /// NM_001271036 /// NM_001271037 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019864 // IgG binding // inferred from electronic annotation 204008_at NM_005740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005740.1 /DEF=Homo sapiens dynein, axonemal, light polypeptide 4 (DNAL4), mRNA. /FEA=mRNA /GEN=DNAL4 /PROD=dynein, axonemal, light polypeptide 4 /DB_XREF=gi:5031666 /UG=Hs.182595 dynein, axonemal, light polypeptide 4 /FL=gb:BC002968.1 gb:NM_005740.1 NM_005740 dynein, axonemal, light chain 4 DNAL4 10126 NM_005740 0007017 // microtubule-based process // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0042623 // ATPase activity, coupled // non-traceable author statement 204009_s_at W80678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W80678 /FEA=EST /DB_XREF=gi:1391858 /DB_XREF=est:zd90d06.s1 /CLONE=IMAGE:356747 /UG=Hs.184050 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog /FL=gb:M54968.1 gb:NM_004985.1 W80678 Kirsten rat sarcoma viral oncogene homolog KRAS 3845 NM_004985 /// NM_033360 /// XM_006719069 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 204010_s_at NM_004985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004985.1 /DEF=Homo sapiens v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog (KRAS2), mRNA. /FEA=mRNA /GEN=KRAS2 /PROD=v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogenehomolog /DB_XREF=gi:4826811 /UG=Hs.184050 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog /FL=gb:M54968.1 gb:NM_004985.1 NM_004985 Kirsten rat sarcoma viral oncogene homolog KRAS 3845 NM_004985 /// NM_033360 /// XM_006719069 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 204011_at NM_005842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005842.1 /DEF=Homo sapiens sprouty (Drosophila) homolog 2 (SPRY2), mRNA. /FEA=mRNA /GEN=SPRY2 /PROD=sprouty (Drosophila) homolog 2 /DB_XREF=gi:5032114 /UG=Hs.18676 sprouty (Drosophila) homolog 2 /FL=gb:AF039843.1 gb:NM_005842.1 NM_005842 sprouty homolog 2 (Drosophila) SPRY2 10253 NM_005842 /// XM_005266217 /// XM_006719752 /// XM_006719753 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0034261 // negative regulation of Ras GTPase activity // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060437 // lung growth // inferred from electronic annotation /// 0060541 // respiratory system development // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred by curator /// 0043539 // protein serine/threonine kinase activator activity // inferred from mutant phenotype 204012_s_at AL529189 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL529189 /FEA=EST /DB_XREF=gi:12792682 /DB_XREF=est:AL529189 /CLONE=CS0DD002YM13 (3 prime) /UG=Hs.200596 KIAA0547 gene product /FL=gb:AB011119.1 gb:NM_014793.1 AL529189 leucine carboxyl methyltransferase 2 LCMT2 9836 NM_014793 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204013_s_at NM_014793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014793.1 /DEF=Homo sapiens KIAA0547 gene product (KIAA0547), mRNA. /FEA=mRNA /GEN=KIAA0547 /PROD=KIAA0547 gene product /DB_XREF=gi:7662173 /UG=Hs.200596 KIAA0547 gene product /FL=gb:AB011119.1 gb:NM_014793.1 NM_014793 leucine carboxyl methyltransferase 2 LCMT2 9836 NM_014793 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204014_at NM_001394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001394.2 /DEF=Homo sapiens dual specificity phosphatase 4 (DUSP4), mRNA. /FEA=mRNA /GEN=DUSP4 /PROD=dual specificity phosphatase 4 /DB_XREF=gi:12707552 /UG=Hs.2359 dual specificity phosphatase 4 /FL=gb:U48807.1 gb:NM_001394.2 gb:BC002671.1 gb:U21108.1 NM_001394 dual specificity phosphatase 4 DUSP4 1846 NM_001394 /// NM_057158 0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 204015_s_at BC002671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002671.1 /DEF=Homo sapiens, dual specificity phosphatase 4, clone MGC:3713, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 4 /DB_XREF=gi:12803670 /UG=Hs.2359 dual specificity phosphatase 4 /FL=gb:U48807.1 gb:NM_001394.2 gb:BC002671.1 gb:U21108.1 BC002671 dual specificity phosphatase 4 DUSP4 1846 NM_001394 /// NM_057158 0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 204016_at NM_015340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015340.1 /DEF=Homo sapiens leucyl-tRNA synthetase, mitochondrial (KIAA0028), mRNA. /FEA=mRNA /GEN=KIAA0028 /PROD=leucyl-tRNA synthetase, mitochondrial /DB_XREF=gi:7661871 /UG=Hs.2450 leucyl-tRNA synthetase, mitochondrial /FL=gb:NM_015340.1 NM_015340 leucyl-tRNA synthetase 2, mitochondrial LARS2 23395 NM_015340 /// XM_005265006 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006429 // leucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004823 // leucine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204017_at NM_006855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006855.2 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (KDELR3), transcript variant 1, mRNA. /FEA=mRNA /GEN=KDELR3 /PROD=KDEL receptor 3, isoform a /DB_XREF=gi:8051612 /UG=Hs.250696 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 /FL=gb:BC001277.1 gb:NM_006855.2 NM_006855 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 KDELR3 11015 NM_006855 /// NM_016657 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046923 // ER retention sequence binding // inferred from electronic annotation 204018_x_at NM_000558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000558.2 /DEF=Homo sapiens hemoglobin, alpha 1 (HBA1), mRNA. /FEA=mRNA /GEN=HBA1 /PROD=hemoglobin, alpha 1 /DB_XREF=gi:6715603 /UG=Hs.251577 hemoglobin, alpha 1 /FL=gb:NM_000558.2 NM_000558 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204019_s_at NM_015677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015677.1 /DEF=Homo sapiens hypothetical protein (DKFZP586F1318), mRNA. /FEA=mRNA /GEN=DKFZP586F1318 /PROD=hypothetical protein /DB_XREF=gi:7661669 /UG=Hs.25213 hypothetical protein /FL=gb:NM_015677.1 NM_015677 SH3 and SYLF domain containing 1 SH3YL1 26751 NM_001159597 /// NM_001282682 /// NM_001282687 /// NM_015677 /// NR_104223 /// NR_104224 /// NR_104225 /// NR_104226 /// NR_104227 0006661 // phosphatidylinositol biosynthetic process // inferred from electronic annotation /// 1900027 // regulation of ruffle assembly // inferred from electronic annotation 0032587 // ruffle membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 204020_at BF739943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF739943 /FEA=EST /DB_XREF=gi:12066607 /DB_XREF=est:7o41b04.x1 /CLONE=IMAGE:3576534 /UG=Hs.29117 purine-rich element binding protein A /FL=gb:M96684.1 gb:NM_005859.1 BF739943 purine-rich element binding protein A PURA 5813 NM_005859 0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0032422 // purine-rich negative regulatory element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation 204021_s_at NM_005859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005859.1 /DEF=Homo sapiens purine-rich element binding protein A (PURA), mRNA. /FEA=mRNA /GEN=PURA /PROD=purine-rich element binding protein A /DB_XREF=gi:5032006 /UG=Hs.29117 purine-rich element binding protein A /FL=gb:M96684.1 gb:NM_005859.1 NM_005859 purine-rich element binding protein A PURA 5813 NM_005859 0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0032422 // purine-rich negative regulatory element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation 204022_at AI668780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI668780 /FEA=EST /DB_XREF=gi:4833554 /DB_XREF=est:wc14b09.x1 /CLONE=IMAGE:2315129 /UG=Hs.315493 Nedd-4-like ubiquitin-protein ligase /FL=gb:U96114.1 gb:NM_007014.2 AI668780 WW domain containing E3 ubiquitin protein ligase 2 WWP2 11060 NM_001270453 /// NM_001270454 /// NM_001270455 /// NM_007014 /// NM_199424 /// XM_005255778 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046718 // viral entry into host cell // traceable author statement /// 0051224 // negative regulation of protein transport // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 204023_at NM_002916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002916.1 /DEF=Homo sapiens replication factor C (activator 1) 4 (37kD) (RFC4), mRNA. /FEA=mRNA /GEN=RFC4 /PROD=replication factor C (activator 1) 4 (37kD) /DB_XREF=gi:4506490 /UG=Hs.35120 replication factor C (activator 1) 4 (37kD) /FL=gb:M87339.1 gb:NM_002916.1 NM_002916 replication factor C (activator 1) 4, 37kDa RFC4 5984 NM_002916 /// NM_181573 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204024_at NM_004337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004337.1 /DEF=Homo sapiens chromosome 8 open reading frame 1 (C8ORF1), mRNA. /FEA=mRNA /GEN=C8ORF1 /PROD=chromosome 8 open reading frame 1 /DB_XREF=gi:4757889 /UG=Hs.40539 chromosome 8 open reading frame 1 /FL=gb:AF061326.1 gb:NM_004337.1 NM_004337 oxidative stress induced growth inhibitor family member 2 OSGIN2 734 NM_001126111 /// NM_004337 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007281 // germ cell development // non-traceable author statement 204025_s_at NM_002598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002598.1 /DEF=Homo sapiens programmed cell death 2 (PDCD2), mRNA. /FEA=mRNA /GEN=PDCD2 /PROD=programmed cell death 2 /DB_XREF=gi:4505654 /UG=Hs.41639 programmed cell death 2 /FL=gb:NM_002598.1 NM_002598 programmed cell death 2 PDCD2 5134 NM_001199461 /// NM_001199462 /// NM_001199463 /// NM_001199464 /// NM_002598 /// NM_144781 /// XM_006715498 /// XR_427972 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204026_s_at NM_007057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007057.1 /DEF=Homo sapiens ZW10 interactor (ZWINT), mRNA. /FEA=mRNA /GEN=ZWINT /PROD=ZW10 interactor /DB_XREF=gi:6857828 /UG=Hs.42650 ZW10 interactor /FL=gb:AF067656.1 gb:NM_007057.1 NM_007057 ZW10 interacting kinetochore protein ZWINT 11130 NM_001005413 /// NM_001005414 /// NM_007057 /// NM_032997 /// XM_005269463 /// XR_428692 /// XR_428693 0000070 // mitotic sister chromatid segregation // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051649 // establishment of localization in cell // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 204027_s_at NM_005371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005371.2 /DEF=Homo sapiens methyltransferase-like 1 (METTL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=METTL1 /PROD=methyltransferase-like protein 1, isoform a /DB_XREF=gi:13186321 /UG=Hs.42957 methyltransferase-like 1 /FL=gb:BC000550.1 gb:NM_005371.2 NM_005371 methyltransferase like 1 METTL1 4234 NM_005371 /// NM_023032 /// NM_023033 /// XM_005268873 0006400 // tRNA modification // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 204028_s_at NM_012197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012197.2 /DEF=Homo sapiens rab6 GTPase activating protein (GAP and centrosome-associated) (GAPCENA), mRNA. /FEA=mRNA /GEN=GAPCENA /PROD=rab6 GTPase activating protein (GAP andcentrosome-associated) /DB_XREF=gi:12232372 /UG=Hs.55099 rab6 GTPase activating protein (GAP and centrosome-associated) /FL=gb:NM_012197.2 NM_012197 RAB GTPase activating protein 1 RABGAP1 23637 NM_012197 /// XM_005251866 /// XM_005251868 /// XM_006717031 /// XM_006717032 0007049 // cell cycle // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // traceable author statement 204029_at NM_001408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001408.1 /DEF=Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog (CELSR2), mRNA. /FEA=mRNA /GEN=CELSR2 /PROD=cadherin EGF LAG seven-pass G-type receptor 2 /DB_XREF=gi:13325063 /UG=Hs.57652 cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog /FL=gb:NM_001408.1 NM_001408 cadherin, EGF LAG seven-pass G-type receptor 2 CELSR2 1952 NM_001408 /// XM_005270580 /// XM_006710405 0001764 // neuron migration // inferred from electronic annotation /// 0003341 // cilium movement // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from sequence or structural similarity /// 0021591 // ventricular system development // inferred from electronic annotation /// 0021999 // neural plate anterior/posterior regionalization // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033326 // cerebrospinal fluid secretion // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204030_s_at NM_014575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014575.1 /DEF=Homo sapiens schwannomin interacting protein 1 (SCHIP-1), mRNA. /FEA=mRNA /GEN=SCHIP-1 /PROD=schwannomin interacting protein 1 /DB_XREF=gi:7657539 /UG=Hs.61490 schwannomin interacting protein 1 /FL=gb:AF145713.1 gb:NM_014575.1 NM_014575 IQCJ-SCHIP1 readthrough /// schwannomin interacting protein 1 IQCJ-SCHIP1 /// SCHIP1 29970 /// 100505385 NM_001197107 /// NM_001197108 /// NM_001197109 /// NM_001197113 /// NM_001197114 /// NM_014575 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204031_s_at NM_005016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005016.1 /DEF=Homo sapiens poly(rC)-binding protein 2 (PCBP2), mRNA. /FEA=mRNA /GEN=PCBP2 /PROD=poly(rC)-binding protein 2 /DB_XREF=gi:4826885 /UG=Hs.63525 poly(rC)-binding protein 2 /FL=gb:BC001155.1 gb:NM_005016.1 NM_005016 poly(rC) binding protein 2 PCBP2 5094 NM_001098620 /// NM_001128911 /// NM_001128912 /// NM_001128913 /// NM_001128914 /// NM_005016 /// NM_031989 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204032_at NM_003567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003567.1 /DEF=Homo sapiens breast cancer anti-estrogen resistance 3 (BCAR3), mRNA. /FEA=mRNA /GEN=BCAR3 /PROD=breast cancer antiestrogen resistance 3 /DB_XREF=gi:4502370 /UG=Hs.6564 breast cancer anti-estrogen resistance 3 /FL=gb:U92715.1 gb:NM_003567.1 gb:AF124250.1 NM_003567 breast cancer anti-estrogen resistance 3 BCAR3 8412 NM_001261408 /// NM_001261409 /// NM_001261410 /// NM_003567 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204033_at NM_004237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004237.1 /DEF=Homo sapiens thyroid hormone receptor interactor 13 (TRIP13), mRNA. /FEA=mRNA /GEN=TRIP13 /PROD=thyroid hormone receptor interactor 13 /DB_XREF=gi:11321606 /UG=Hs.6566 thyroid hormone receptor interactor 13 /FL=gb:NM_004237.1 gb:BC000404.1 gb:U96131.1 NM_004237 thyroid hormone receptor interactor 13 TRIP13 9319 NM_001166260 /// NM_004237 /// XM_005248388 0001556 // oocyte maturation // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // inferred from sequence or structural similarity /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007286 // spermatid development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204034_at NM_014297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014297.1 /DEF=Homo sapiens protein expressed in thyroid (YF13H12), mRNA. /FEA=mRNA /GEN=YF13H12 /PROD=protein expressed in thyroid /DB_XREF=gi:7657686 /UG=Hs.7486 protein expressed in thyroid /FL=gb:NM_014297.1 NM_014297 ethylmalonic encephalopathy 1 ETHE1 23474 NM_014297 /// XM_005258687 /// XM_005258688 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement /// 0070813 // hydrogen sulfide metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0005506 // iron ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050313 // sulfur dioxygenase activity // inferred from direct assay /// 0050313 // sulfur dioxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 204035_at NM_003469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003469.2 /DEF=Homo sapiens secretogranin II (chromogranin C) (SCG2), mRNA. /FEA=mRNA /GEN=SCG2 /PROD=secretogranin II precursor /DB_XREF=gi:10800415 /UG=Hs.75426 secretogranin II (chromogranin C) /FL=gb:NM_003469.2 gb:M25756.1 NM_003469 secretogranin II SCG2 7857 NM_003469 0000165 // MAPK cascade // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006928 // cellular component movement // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0009306 // protein secretion // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043542 // endothelial cell migration // traceable author statement /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay 204036_at AW269335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW269335 /FEA=EST /DB_XREF=gi:6656365 /DB_XREF=est:xs47d05.x1 /CLONE=IMAGE:2772777 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1 AW269335 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204037_at BF055366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055366 /FEA=EST /DB_XREF=gi:10809262 /DB_XREF=est:7j78f10.x1 /CLONE=IMAGE:3392587 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1 BF055366 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204038_s_at NM_001401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001401.1 /DEF=Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 (EDG2), mRNA. /FEA=mRNA /GEN=EDG2 /PROD=endothelial differentiation, lysophosphatidicacid G-protein-coupled receptor, 2 /DB_XREF=gi:4503456 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1 NM_001401 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204039_at NM_004364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004364.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), alpha (CEBPA), mRNA. /FEA=mRNA /GEN=CEBPA /PROD=CCAATenhancer binding protein (CEBP), alpha /DB_XREF=gi:4757971 /UG=Hs.76171 CCAATenhancer binding protein (CEBP), alpha /FL=gb:NM_004364.1 NM_004364 CCAAT/enhancer binding protein (C/EBP), alpha CEBPA 1050 NM_001285829 /// NM_001287424 /// NM_001287435 /// NM_004364 0000050 // urea cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030099 // myeloid cell differentiation // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033274 // response to vitamin B2 // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0048469 // cell maturation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0035189 // Rb-E2F complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 204040_at NM_014746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014746.1 /DEF=Homo sapiens KIAA0161 gene product (KIAA0161), mRNA. /FEA=mRNA /GEN=KIAA0161 /PROD=KIAA0161 gene product /DB_XREF=gi:7661955 /UG=Hs.78894 KIAA0161 gene product /FL=gb:D79983.1 gb:NM_014746.1 NM_014746 ring finger protein 144A RNF144A 9781 NM_014746 /// XM_005246200 /// XM_005246201 /// XM_005246202 /// XM_005246203 /// XM_006711909 0016567 // protein ubiquitination // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204041_at NM_000898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000898.1 /DEF=Homo sapiens monoamine oxidase B (MAOB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOB /PROD=monoamine oxidase B /DB_XREF=gi:4505092 /UG=Hs.82163 monoamine oxidase B /FL=gb:M69177.1 gb:NM_000898.1 NM_000898 monoamine oxidase B MAOB 4129 NM_000898 /// XM_005272607 /// XM_005272608 0006805 // xenobiotic metabolic process // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010044 // response to aluminum ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0014063 // negative regulation of serotonin secretion // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045964 // positive regulation of dopamine metabolic process // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008131 // primary amine oxidase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204042_at AB020707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020707.1 /DEF=Homo sapiens mRNA for KIAA0900 protein, partial cds. /FEA=mRNA /GEN=KIAA0900 /PROD=KIAA0900 protein /DB_XREF=gi:4240288 /UG=Hs.82318 WAS protein family, member 3 /FL=gb:NM_006646.2 gb:AB026543.1 AB020707 WAS protein family, member 3 WASF3 10810 NM_001291965 /// NM_006646 /// XM_005266239 0006461 // protein complex assembly // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // traceable author statement /// 0031643 // positive regulation of myelination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 204043_at NM_000355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000355.1 /DEF=Homo sapiens transcobalamin II; macrocytic anemia (TCN2), mRNA. /FEA=mRNA /GEN=TCN2 /PROD=transcobalamin II /DB_XREF=gi:4507408 /UG=Hs.84232 transcobalamin II; macrocytic anemia /FL=gb:BC001176.1 gb:M60396.1 gb:L02647.1 gb:L02648.1 gb:NM_000355.1 NM_000355 transcobalamin II TCN2 6948 NM_000355 /// NM_001184726 /// NM_001190420 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // not recorded /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005768 // endosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0031419 // cobalamin binding // not recorded /// 0031419 // cobalamin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204044_at NM_014298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014298.2 /DEF=Homo sapiens quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) (QPRT), mRNA. /FEA=mRNA /GEN=QPRT /PROD=quinolinate phosphoribosyltransferase /DB_XREF=gi:9257236 /UG=Hs.8935 quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) /FL=gb:D78177.1 gb:BC005060.1 gb:NM_014298.2 NM_014298 quinolinate phosphoribosyltransferase QPRT 23475 NM_014298 /// XM_005255223 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0034213 // quinolinate catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046874 // quinolinate metabolic process // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 204045_at NM_004780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004780.1 /DEF=Homo sapiens transcription elongation factor A (SII)-like 1 (TCEAL1), mRNA. /FEA=mRNA /GEN=TCEAL1 /PROD=transcription elongation factor A (SII)-like 1 /DB_XREF=gi:4759215 /UG=Hs.95243 transcription elongation factor A (SII)-like 1 /FL=gb:BC000809.1 gb:NM_004780.1 gb:M99701.1 NM_004780 transcription elongation factor A (SII)-like 1 TCEAL1 9338 NM_001006639 /// NM_001006640 /// NM_004780 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement 204046_at NM_004573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004573.1 /DEF=Homo sapiens phospholipase C, beta 2 (PLCB2), mRNA. /FEA=mRNA /GEN=PLCB2 /PROD=phospholipase C, beta 2 /DB_XREF=gi:4758937 /UG=Hs.994 phospholipase C, beta 2 /FL=gb:M95678.1 gb:NM_004573.1 NM_004573 phospholipase C, beta 2 PLCB2 5330 NM_001284297 /// NM_001284298 /// NM_001284299 /// NM_004573 /// XM_005254448 /// XM_005254449 /// XM_005254450 /// XM_006720571 /// XM_006720572 /// XR_243102 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204047_s_at AW295193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW295193 /FEA=EST /DB_XREF=gi:6701829 /DB_XREF=est:UI-H-BI2-aib-f-02-0-UI.s1 /CLONE=IMAGE:2728827 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1 AW295193 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204048_s_at AA551142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA551142 /FEA=EST /DB_XREF=gi:2321394 /DB_XREF=est:nk76a03.s1 /CLONE=IMAGE:1019404 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1 AA551142 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204049_s_at NM_014721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014721.1 /DEF=Homo sapiens KIAA0680 gene product (KIAA0680), mRNA. /FEA=mRNA /GEN=KIAA0680 /PROD=KIAA0680 gene product /DB_XREF=gi:7662247 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1 NM_014721 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204050_s_at NM_001833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001833.1 /DEF=Homo sapiens clathrin, light polypeptide (Lca) (CLTA), transcript variant nonbrain, mRNA. /FEA=mRNA /GEN=CLTA /PROD=clathrin, light polypeptide A (Lca) isoform a /DB_XREF=gi:4502898 /UG=Hs.104143 clathrin, light polypeptide (Lca) /FL=gb:M20472.1 gb:NM_001833.1 NM_001833 clathrin, light chain A CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 204051_s_at AW089415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW089415 /FEA=EST /DB_XREF=gi:6046759 /DB_XREF=est:xd05c09.x1 /CLONE=IMAGE:2592880 /UG=Hs.105700 secreted frizzled-related protein 4 /FL=gb:AF026692.1 gb:NM_003014.2 AW089415 secreted frizzled-related protein 4 SFRP4 6424 NM_003014 0001944 // vasculature development // not recorded /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008406 // gonad development // not recorded /// 0009725 // response to hormone // non-traceable author statement /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0022601 // menstrual cycle phase // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045606 // positive regulation of epidermal cell differentiation // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // not recorded /// 0046697 // decidualization // not recorded /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from direct assay /// 2000119 // negative regulation of sodium-dependent phosphate transport // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 204052_s_at NM_003014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003014.2 /DEF=Homo sapiens secreted frizzled-related protein 4 (SFRP4), mRNA. /FEA=mRNA /GEN=SFRP4 /PROD=secreted frizzled-related protein 4 /DB_XREF=gi:8400733 /UG=Hs.105700 secreted frizzled-related protein 4 /FL=gb:AF026692.1 gb:NM_003014.2 NM_003014 secreted frizzled-related protein 4 SFRP4 6424 NM_003014 0001944 // vasculature development // not recorded /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008406 // gonad development // not recorded /// 0009725 // response to hormone // non-traceable author statement /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0022601 // menstrual cycle phase // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045606 // positive regulation of epidermal cell differentiation // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // not recorded /// 0046697 // decidualization // not recorded /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from direct assay /// 2000119 // negative regulation of sodium-dependent phosphate transport // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 204053_x_at U96180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96180.1 /DEF=Human protein tyrosine phosphatase (TEP1) mRNA, complete cds. /FEA=mRNA /GEN=TEP1 /PROD=protein tyrosine phosphatase /DB_XREF=gi:2039369 /UG=Hs.10712 phosphatase and tensin homolog (mutated in multiple advanced cancers 1) /FL=gb:U92436.1 gb:U93051.1 gb:U96180.1 gb:NM_000314.1 U96180 phosphatase and tensin homolog PTEN 5728 NM_000314 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement 204054_at NM_000314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000314.1 /DEF=Homo sapiens phosphatase and tensin homolog (mutated in multiple advanced cancers 1) (PTEN), mRNA. /FEA=mRNA /GEN=PTEN /PROD=phosphatase and tensin homolog (mutated inmultiple advanced cancers 1) /DB_XREF=gi:4506248 /UG=Hs.10712 phosphatase and tensin homolog (mutated in multiple advanced cancers 1) /FL=gb:U92436.1 gb:U93051.1 gb:U96180.1 gb:NM_000314.1 NM_000314 phosphatase and tensin homolog PTEN 5728 NM_000314 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement 204055_s_at NM_005930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005930.1 /DEF=Homo sapiens meningioma expressed antigen 6 (coiled-coil proline-rich) (MGEA6), mRNA. /FEA=mRNA /GEN=MGEA6 /PROD=meningioma expressed antigen 6 (coiled-coilproline-rich) /DB_XREF=gi:5174560 /UG=Hs.117242 meningioma expressed antigen 6 (coiled-coil proline-rich) /FL=gb:U94780.1 gb:NM_005930.1 NM_005930 CTAGE family, member 5 CTAGE5 4253 NM_001247988 /// NM_001247989 /// NM_001247990 /// NM_005930 /// NM_203354 /// NM_203355 /// NM_203356 /// NM_203357 /// XM_005267646 /// XM_005267647 /// XM_005267648 /// XM_005267649 /// XM_005267650 /// XM_006720148 0043085 // positive regulation of catalytic activity // traceable author statement 0016020 // membrane // inferred from direct assay 0008047 // enzyme activator activity // traceable author statement 204056_s_at NM_000431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000431.1 /DEF=Homo sapiens mevalonate kinase (mevalonic aciduria) (MVK), mRNA. /FEA=mRNA /GEN=MVK /PROD=mevalonate kinase /DB_XREF=gi:4557768 /UG=Hs.130607 mevalonate kinase (mevalonic aciduria) /FL=gb:M88468.1 gb:NM_000431.1 NM_000431 mevalonate kinase MVK 4598 NM_000431 /// NM_001114185 /// XM_005253883 /// XM_005253884 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004496 // mevalonate kinase activity // inferred from direct assay /// 0004496 // mevalonate kinase activity // inferred from mutant phenotype /// 0004496 // mevalonate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 204057_at AI073984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073984 /FEA=EST /DB_XREF=gi:3400628 /DB_XREF=est:oy66c05.x1 /CLONE=IMAGE:1670792 /UG=Hs.14453 interferon consensus sequence binding protein 1 /FL=gb:M91196.1 gb:NM_002163.1 AI073984 interferon regulatory factor 8 IRF8 3394 NM_002163 /// XM_006721187 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204058_at AL049699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049699 /DEF=Human DNA sequence from clone 747H23 on chromosome 6q13-15. Contains the 3 part of the ME1 gene for malic enzyme 1, soluble (NADP-dependent malic enzyme, malate oxidoreductase, EC 1.1.1.40), a novel gene and the 5 part of the gene for N-acetylgl... /FEA=mRNA_3 /DB_XREF=gi:5419832 /UG=Hs.14732 malic enzyme 1, NADP(+)-dependent, cytosolic /FL=gb:NM_002395.2 AL049699 malic enzyme 1, NADP(+)-dependent, cytosolic ME1 4199 NM_002395 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006108 // malate metabolic process // inferred from direct assay /// 0006741 // NADP biosynthetic process // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from sequence or structural similarity /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043531 // ADP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0051287 // NAD binding // traceable author statement 204059_s_at NM_002395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002395.2 /DEF=Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic (ME1), mRNA. /FEA=mRNA /GEN=ME1 /PROD=cytosolic malic enzyme 1 /DB_XREF=gi:13435400 /UG=Hs.14732 malic enzyme 1, NADP(+)-dependent, cytosolic /FL=gb:NM_002395.2 NM_002395 malic enzyme 1, NADP(+)-dependent, cytosolic ME1 4199 NM_002395 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006108 // malate metabolic process // inferred from direct assay /// 0006741 // NADP biosynthetic process // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from sequence or structural similarity /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043531 // ADP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0051287 // NAD binding // traceable author statement 204060_s_at NM_005044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005044.1 /DEF=Homo sapiens protein kinase, X-linked (PRKX), mRNA. /FEA=mRNA /GEN=PRKX /PROD=protein kinase, X-linked /DB_XREF=gi:4826947 /UG=Hs.147996 protein kinase, X-linked /FL=gb:NM_005044.1 NM_005044 protein kinase, X-linked /// protein kinase, Y-linked, pseudogene PRKX /// PRKY 5613 /// 5616 NM_002760 /// NM_005044 /// NR_028062 /// XM_005274560 /// XM_005274561 0001525 // angiogenesis // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030334 // regulation of cell migration // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060562 // epithelial tube morphogenesis // inferred from direct assay /// 0060993 // kidney morphogenesis // inferred from direct assay /// 2000696 // regulation of epithelial cell differentiation involved in kidney development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 204061_at NM_005044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005044.1 /DEF=Homo sapiens protein kinase, X-linked (PRKX), mRNA. /FEA=mRNA /GEN=PRKX /PROD=protein kinase, X-linked /DB_XREF=gi:4826947 /UG=Hs.147996 protein kinase, X-linked /FL=gb:NM_005044.1 NM_005044 protein kinase, X-linked PRKX 5613 NM_005044 /// XM_005274560 /// XM_005274561 0001525 // angiogenesis // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030334 // regulation of cell migration // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060562 // epithelial tube morphogenesis // inferred from direct assay /// 0060993 // kidney morphogenesis // inferred from direct assay /// 2000696 // regulation of epithelial cell differentiation involved in kidney development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 204062_s_at BG526973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG526973 /FEA=EST /DB_XREF=gi:13518510 /DB_XREF=est:602556210F1 /CLONE=IMAGE:4685114 /UG=Hs.151406 KIAA0623 gene product /FL=gb:AB014523.1 gb:NM_014683.1 BG526973 unc-51 like autophagy activating kinase 2 ULK2 9706 NM_001142610 /// NM_014683 /// XM_006721606 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204063_s_at NM_014683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014683.1 /DEF=Homo sapiens KIAA0623 gene product (KIAA0623), mRNA. /FEA=mRNA /GEN=KIAA0623 /PROD=KIAA0623 gene product /DB_XREF=gi:7662209 /UG=Hs.151406 KIAA0623 gene product /FL=gb:AB014523.1 gb:NM_014683.1 NM_014683 unc-51 like autophagy activating kinase 2 ULK2 9706 NM_001142610 /// NM_014683 /// XM_006721606 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204064_at NM_005131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005131.1 /DEF=Homo sapiens nuclear matrix protein p84 (P84), mRNA. /FEA=mRNA /GEN=P84 /PROD=nuclear matrix protein p84 /DB_XREF=gi:4826881 /UG=Hs.1540 nuclear matrix protein p84 /FL=gb:NM_005131.1 gb:L36529.1 NM_005131 THO complex 1 THOC1 9984 NM_005131 0000018 // regulation of DNA recombination // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0048297 // negative regulation of isotype switching to IgA isotypes // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204065_at NM_004854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004854.1 /DEF=Homo sapiens HNK-1 sulfotransferase (HNK-1ST), mRNA. /FEA=mRNA /GEN=HNK-1ST /PROD=HNK-1 sulfotransferase /DB_XREF=gi:4758539 /UG=Hs.155553 HNK-1 sulfotransferase /FL=gb:AF033827.1 gb:AF070594.1 gb:NM_004854.1 NM_004854 carbohydrate sulfotransferase 10 CHST10 9486 NM_004854 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0016232 // HNK-1 sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204066_s_at NM_014914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014914.1 /DEF=Homo sapiens KIAA1099 protein (KIAA1099), mRNA. /FEA=mRNA /GEN=KIAA1099 /PROD=KIAA1099 protein /DB_XREF=gi:7662483 /UG=Hs.159377 KIAA1099 protein /FL=gb:AB029022.1 gb:NM_014914.1 NM_014914 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 AGAP1 116987 NM_001037131 /// NM_001244888 /// NM_014914 /// XM_005246058 /// XM_005246059 /// XM_006712234 /// XM_006712235 /// XM_006712236 /// XM_006712237 /// XM_006712238 /// XM_006712239 /// XM_006712240 /// XM_006712241 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204067_at AA129776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129776 /FEA=EST /DB_XREF=gi:1690187 /DB_XREF=est:zl16h11.s1 /CLONE=IMAGE:502149 /UG=Hs.16340 sulfite oxidase /FL=gb:NM_000456.1 gb:L31573.1 AA129776 sulfite oxidase SUOX 6821 NM_000456 /// NM_001032386 /// NM_001032387 /// XM_005269112 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0008482 // sulfite oxidase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204068_at NM_006281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006281.1 /DEF=Homo sapiens serinethreonine kinase 3 (Ste20, yeast homolog) (STK3), mRNA. /FEA=mRNA /GEN=STK3 /PROD=serinethreonine kinase 3 (Ste20, yeasthomolog) /DB_XREF=gi:5454093 /UG=Hs.166684 serinethreonine kinase 3 (Ste20, yeast homolog) /FL=gb:U26424.1 gb:U60206.1 gb:NM_006281.1 NM_006281 serine/threonine kinase 3 STK3 6788 NM_001256312 /// NM_001256313 /// NM_006281 /// XM_005251034 0001841 // neural tube formation // inferred from electronic annotation /// 0003157 // endocardium development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 204069_at NM_002398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002398.1 /DEF=Homo sapiens Meis1 (mouse) homolog (MEIS1), mRNA. /FEA=mRNA /GEN=MEIS1 /PROD=Meis1 homolog /DB_XREF=gi:4505150 /UG=Hs.170177 Meis1 (mouse) homolog /FL=gb:U85707.1 gb:NM_002398.1 NM_002398 Meis homeobox 1 MEIS1 4211 NM_002398 /// XM_005264321 /// XM_005264322 /// XM_005264323 /// XM_005264324 /// XM_005264325 /// XM_006712020 /// XR_244932 /// XR_244933 0001525 // angiogenesis // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204070_at NM_004585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004585.2 /DEF=Homo sapiens retinoic acid receptor responder (tazarotene induced) 3 (RARRES3), mRNA. /FEA=mRNA /GEN=RARRES3 /PROD=retinoic acid receptor responder (tazaroteneinduced) 3 /DB_XREF=gi:8051633 /UG=Hs.17466 retinoic acid receptor responder (tazarotene induced) 3 /FL=gb:AF060228.1 gb:AF092922.1 gb:NM_004585.2 gb:AB030815.1 NM_004585 retinoic acid receptor responder (tazarotene induced) 3 RARRES3 5920 NM_004585 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 204071_s_at NM_005802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005802.1 /DEF=Homo sapiens tumor protein p53-binding protein (TP53BPL), mRNA. /FEA=mRNA /GEN=TP53BPL /PROD=tumor protein p53-binding protein /DB_XREF=gi:5032190 /UG=Hs.179982 tumor protein p53-binding protein /FL=gb:U82939.1 gb:AF098300.1 gb:NM_005802.1 gb:AB045732.1 NM_005802 topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase TOPORS 10210 NM_001195622 /// NM_005802 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0035845 // photoreceptor cell outer segment organization // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005868 // cytoplasmic dynein complex // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019789 // SUMO ligase activity // inferred from mutant phenotype /// 0044547 // DNA topoisomerase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204072_s_at NM_023037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023037.1 /DEF=Homo sapiens putative gene product (13CDNA73), mRNA. /FEA=mRNA /GEN=13CDNA73 /PROD=putative gene product /DB_XREF=gi:12957487 /UG=Hs.181304 putative gene product /FL=gb:NM_023037.1 NM_023037 furry homolog (Drosophila) FRY 10129 NM_023037 /// XM_006719749 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 204073_s_at NM_013279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013279.1 /DEF=Homo sapiens chromosome 11open reading frame 9 (C11ORF9), mRNA. /FEA=mRNA /GEN=C11ORF9 /PROD=chromosome 11open reading frame 9 /DB_XREF=gi:7019334 /UG=Hs.184640 chromosome 11open reading frame 9 /FL=gb:BC004938.1 gb:AF086762.1 gb:NM_013279.1 NM_013279 myelin regulatory factor MYRF 745 NM_001127392 /// NM_013279 /// XM_005274222 /// XM_005274223 /// XM_005274224 /// XM_005274225 /// XM_005274226 /// XM_005274227 /// XM_005274228 /// XM_005274229 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from sequence or structural similarity /// 0022010 // central nervous system myelination // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204074_s_at AI936976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI936976 /FEA=EST /DB_XREF=gi:5675846 /DB_XREF=est:wp71f07.x1 /CLONE=IMAGE:2467237 /UG=Hs.200595 KIAA0562 gene product /FL=gb:AB011134.1 gb:NM_014704.1 AI936976 centrosomal protein 104kDa CEP104 9731 NM_014704 /// XM_005244815 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016596 // thienylcyclohexylpiperidine binding // inferred from electronic annotation 204075_s_at NM_014704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014704.1 /DEF=Homo sapiens KIAA0562 gene product (KIAA0562), mRNA. /FEA=mRNA /GEN=KIAA0562 /PROD=KIAA0562 gene product /DB_XREF=gi:7662179 /UG=Hs.200595 KIAA0562 gene product /FL=gb:AB011134.1 gb:NM_014704.1 NM_014704 centrosomal protein 104kDa CEP104 9731 NM_014704 /// XM_005244815 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016596 // thienylcyclohexylpiperidine binding // inferred from electronic annotation 204076_at AB002390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002390.1 /DEF=Human mRNA for KIAA0392 gene, partial cds. /FEA=mRNA /GEN=KIAA0392 /DB_XREF=gi:2280487 /UG=Hs.201377 apyrase, lysosomal /FL=gb:AF016032.1 gb:NM_004901.1 AB002390 ectonucleoside triphosphate diphosphohydrolase 4 ENTPD4 9583 NM_001128930 /// NM_004901 0006256 // UDP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from direct assay 204077_x_at NM_004901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004901.1 /DEF=Homo sapiens apyrase, lysosomal (LAP70), mRNA. /FEA=mRNA /GEN=LAP70 /PROD=apyrase, lysosomal /DB_XREF=gi:4758661 /UG=Hs.201377 apyrase, lysosomal /FL=gb:AF016032.1 gb:NM_004901.1 NM_004901 ectonucleoside triphosphate diphosphohydrolase 4 ENTPD4 9583 NM_001128930 /// NM_004901 0006256 // UDP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from direct assay 204078_at NM_006455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006455.1 /DEF=Homo sapiens nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein (SC65), mRNA. /FEA=mRNA /GEN=SC65 /PROD=nucleolar autoantigen (55kD) similar to ratsynaptonemal complex protein /DB_XREF=gi:5454037 /UG=Hs.207251 nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein /FL=gb:BC001047.1 gb:U47621.1 gb:NM_006455.1 NM_006455 leprecan-like 4 LEPREL4 10609 NM_006455 /// XM_005256952 /// XM_005256953 /// XM_006721640 0007130 // synaptonemal complex assembly // traceable author statement 0000794 // condensed nuclear chromosome // traceable author statement /// 0000795 // synaptonemal complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 204079_at NM_003595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003595.1 /DEF=Homo sapiens tyrosylprotein sulfotransferase 2 (TPST2), mRNA. /FEA=mRNA /GEN=TPST2 /PROD=tyrosylprotein sulfotransferase 2 /DB_XREF=gi:4507666 /UG=Hs.26350 tyrosylprotein sulfotransferase 2 /FL=gb:AL136623.1 gb:BC001057.1 gb:AF061254.1 gb:AF049891.1 gb:NM_003595.1 NM_003595 tyrosylprotein sulfotransferase 2 TPST2 8459 NM_001008566 /// NM_003595 /// XM_006724338 0006478 // peptidyl-tyrosine sulfation // inferred from electronic annotation /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0060468 // prevention of polyspermy // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008476 // protein-tyrosine sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204080_at NM_025077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025077.1 /DEF=Homo sapiens hypothetical protein FLJ13949 (FLJ13949), mRNA. /FEA=mRNA /GEN=FLJ13949 /PROD=hypothetical protein FLJ13949 /DB_XREF=gi:13376627 /UG=Hs.288198 hypothetical protein FLJ13949 /FL=gb:NM_025077.1 NM_025077 target of EGR1, member 1 (nuclear) TOE1 114034 NM_025077 /// XM_005270412 /// XM_005270413 /// XR_246230 /// XR_426587 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204081_at NM_006176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006176.1 /DEF=Homo sapiens neurogranin (protein kinase C substrate, RC3) (NRGN), mRNA. /FEA=mRNA /GEN=NRGN /PROD=neurogranin /DB_XREF=gi:5453799 /UG=Hs.26944 neurogranin (protein kinase C substrate, RC3) /FL=gb:BC002835.1 gb:U89165.1 gb:NM_006176.1 NM_006176 neurogranin (protein kinase C substrate, RC3) NRGN 4900 NM_001126181 /// NM_006176 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 204082_at NM_006195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006195.1 /DEF=Homo sapiens pre-B-cell leukemia transcription factor 3 (PBX3), mRNA. /FEA=mRNA /GEN=PBX3 /PROD=pre-B-cell leukemia transcription factor 3 /DB_XREF=gi:5453851 /UG=Hs.294101 pre-B-cell leukemia transcription factor 3 /FL=gb:NM_006195.1 NM_006195 pre-B-cell leukemia homeobox 3 PBX3 5090 NM_001134778 /// NM_006195 /// NR_024122 /// NR_024123 /// XM_006717130 /// XM_006717131 /// XM_006717132 /// XM_006717133 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007387 // anterior compartment pattern formation // traceable author statement /// 0007388 // posterior compartment specification // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021516 // dorsal spinal cord development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204083_s_at NM_003289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003289.1 /DEF=Homo sapiens tropomyosin 2 (beta) (TPM2), mRNA. /FEA=mRNA /GEN=TPM2 /PROD=tropomyosin 2 (beta) /DB_XREF=gi:4507648 /UG=Hs.300772 tropomyosin 2 (beta) /FL=gb:M75165.1 gb:M12125.1 gb:M74817.1 gb:NM_003289.1 NM_003289 tropomyosin 2 (beta) TPM2 7169 NM_001145822 /// NM_003289 /// NM_213674 /// XM_005251566 /// XM_005251567 /// XM_005251568 /// XM_005251569 /// XM_005251570 /// XM_005251571 /// XM_005251572 0006936 // muscle contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0043462 // regulation of ATPase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005862 // muscle thin filament tropomyosin // traceable author statement 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement 204084_s_at AI911687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI911687 /FEA=EST /DB_XREF=gi:5631542 /DB_XREF=est:wc71g01.x1 /CLONE=IMAGE:2324112 /UG=Hs.30213 ceroid-lipofuscinosis, neuronal 5 /FL=gb:AF068227.1 gb:NM_006493.1 AI911687 ceroid-lipofuscinosis, neuronal 5 CLN5 1203 NM_006493 0006465 // signal peptide processing // inferred from direct assay /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007601 // visual perception // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from expression pattern /// 0030163 // protein catabolic process // non-traceable author statement /// 0042551 // neuron maturation // non-traceable author statement /// 0070085 // glycosylation // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005775 // vacuolar lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay 204085_s_at NM_006493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006493.1 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 5 (CLN5), mRNA. /FEA=mRNA /GEN=CLN5 /PROD=ceroid-lipofuscinosis, neuronal 5 /DB_XREF=gi:5729771 /UG=Hs.30213 ceroid-lipofuscinosis, neuronal 5 /FL=gb:AF068227.1 gb:NM_006493.1 NM_006493 ceroid-lipofuscinosis, neuronal 5 CLN5 1203 NM_006493 0006465 // signal peptide processing // inferred from direct assay /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007601 // visual perception // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from expression pattern /// 0030163 // protein catabolic process // non-traceable author statement /// 0042551 // neuron maturation // non-traceable author statement /// 0070085 // glycosylation // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005775 // vacuolar lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay 204086_at NM_006115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006115.1 /DEF=Homo sapiens preferentially expressed antigen in melanoma (PRAME), mRNA. /FEA=mRNA /GEN=PRAME /PROD=preferentially expressed antigen of melanoma /DB_XREF=gi:5174640 /UG=Hs.30743 preferentially expressed antigen in melanoma /FL=gb:U65011.1 gb:NM_006115.1 NM_006115 preferentially expressed antigen in melanoma PRAME 23532 NM_001291715 /// NM_001291716 /// NM_001291717 /// NM_001291719 /// NM_006115 /// NM_206953 /// NM_206954 /// NM_206955 /// NM_206956 /// XM_006725402 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from direct assay 204087_s_at NM_021095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021095.1 /DEF=Homo sapiens solute carrier family 5 (sodium-dependent vitamin transporter), member 6 (SLC5A6), mRNA. /FEA=mRNA /GEN=SLC5A6 /PROD=solute carrier family 5 (sodium-dependentvitamin transporter), member 6 /DB_XREF=gi:10863878 /UG=Hs.321579 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 /FL=gb:NM_021095.1 gb:AF069307.1 gb:AF081571.1 NM_021095 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 SLC5A6 8884 NM_021095 /// NR_028323 /// XM_006712128 /// XM_006712129 /// XM_006712130 /// XM_006712131 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0015878 // biotin transport // inferred from electronic annotation /// 0015887 // pantothenate transmembrane transport // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008523 // sodium-dependent multivitamin transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 204088_at NM_002560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002560.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), mRNA. /FEA=mRNA /GEN=P2RX4 /PROD=purinergic receptor P2X, ligand-gated ionchannel, 4 /DB_XREF=gi:4505548 /UG=Hs.321709 purinergic receptor P2X, ligand-gated ion channel, 4 /FL=gb:U83993.1 gb:NM_002560.1 NM_002560 purinergic receptor P2X, ligand-gated ion channel, 4 P2RX4 5025 NM_001256796 /// NM_001261397 /// NM_001261398 /// NM_002560 /// NM_175567 /// NM_175568 /// NR_046372 /// NR_046373 /// XR_429105 0001894 // tissue homeostasis // non-traceable author statement /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from mutant phenotype /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0032308 // positive regulation of prostaglandin secretion // non-traceable author statement /// 0033198 // response to ATP // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from direct assay /// 0034405 // response to fluid shear stress // inferred from direct assay /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from mutant phenotype /// 0042118 // endothelial cell activation // traceable author statement /// 0042311 // vasodilation // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // inferred from direct assay /// 0050850 // positive regulation of calcium-mediated signaling // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // non-traceable author statement /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0055119 // relaxation of cardiac muscle // inferred from mutant phenotype /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071318 // cellular response to ATP // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005639 // integral component of nuclear inner membrane // not recorded /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // inferred from direct assay /// 0001614 // purinergic nucleotide receptor activity // inferred from mutant phenotype /// 0004931 // extracellular ATP-gated cation channel activity // inferred from direct assay /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred by curator /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0045296 // cadherin binding // inferred from physical interaction 204089_x_at NM_006724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006724.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 4 (MAP3K4), transcript variant 2, mRNA. /FEA=mRNA /GEN=MAP3K4 /PROD=MAPERK kinase kinase 4, isoform b /DB_XREF=gi:6031179 /UG=Hs.32353 mitogen-activated protein kinase kinase kinase 4 /FL=gb:NM_006724.1 gb:AF116604.1 NM_006724 mitogen-activated protein kinase kinase kinase 4 MAP3K4 4216 NM_001291958 /// NM_005922 /// NM_006724 /// NR_120425 /// XM_005266988 /// XM_005266989 /// XR_245517 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019100 // male germ-line sex determination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0060718 // chorionic trophoblast cell differentiation // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204090_at NM_004197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004197.1 /DEF=Homo sapiens serinethreonine kinase 19 (STK19), mRNA. /FEA=mRNA /GEN=STK19 /PROD=serinethreonine kinase 19 /DB_XREF=gi:4759179 /UG=Hs.444 serinethreonine kinase 19 /FL=gb:L26260.1 gb:NM_004197.1 NM_004197 serine/threonine kinase 19 STK19 8859 NM_004197 /// NM_032454 /// NR_026717 0006468 // protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204091_at NM_002601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002601.1 /DEF=Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA. /FEA=mRNA /GEN=PDE6D /PROD=phosphodiesterase 6D, cGMP-specific, rod, delta /DB_XREF=gi:4505670 /UG=Hs.48291 phosphodiesterase 6D, cGMP-specific, rod, delta /FL=gb:AF022912.1 gb:NM_002601.1 NM_002601 phosphodiesterase 6D, cGMP-specific, rod, delta PDE6D 5147 NM_001291018 /// NM_002601 /// NR_110994 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033124 // regulation of GTP catabolic process // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction 204092_s_at NM_003600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003600.1 /DEF=Homo sapiens serinethreonine kinase 15 (STK15), mRNA. /FEA=mRNA /GEN=STK15 /PROD=serinethreonine kinase 15 /DB_XREF=gi:4507274 /UG=Hs.48915 serinethreonine kinase 15 /FL=gb:AF008551.1 gb:AF011468.1 gb:NM_003600.1 NM_003600 aurora kinase A AURKA 6790 NM_003600 /// NM_198433 /// NM_198434 /// NM_198435 /// NM_198436 /// NM_198437 /// XM_005260534 /// XM_006723871 /// XM_006723872 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043146 // spindle stabilization // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // traceable author statement /// 0046605 // regulation of centrosome cycle // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 204093_at NM_001239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001239.1 /DEF=Homo sapiens cyclin H (CCNH), mRNA. /FEA=mRNA /GEN=CCNH /PROD=cyclin H /DB_XREF=gi:4502622 /UG=Hs.514 cyclin H /FL=gb:BC005280.1 gb:NM_001239.1 gb:U12685.1 gb:U11791.1 NM_001239 cyclin H CCNH 902 NM_001199189 /// NM_001239 /// XM_005248627 /// XM_005248629 /// XR_427721 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from electronic annotation /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0070985 // TFIIK complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 204094_s_at NM_014779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014779.1 /DEF=Homo sapiens KIAA0669 gene product (KIAA0669), mRNA. /FEA=mRNA /GEN=KIAA0669 /PROD=KIAA0669 gene product /DB_XREF=gi:7662235 /UG=Hs.52526 KIAA0669 gene product /FL=gb:AB014569.1 gb:NM_014779.1 NM_014779 TSC22 domain family, member 2 TSC22D2 9819 NM_014779 /// XM_005247920 /// XR_427388 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 204095_s_at AL521391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL521391 /FEA=EST /DB_XREF=gi:12784884 /DB_XREF=est:AL521391 /CLONE=CS0DB001YB07 (3 prime) /UG=Hs.5881 ELL gene (11-19 lysine-rich leukemia gene) /FL=gb:AL136771.1 gb:NM_006532.1 gb:U16282.1 AL521391 elongation factor RNA polymerase II ELL 8178 NM_006532 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0008023 // transcription elongation factor complex // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 204096_s_at AL136771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136771.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I1916 (from clone DKFZp434I1916); complete cds. /FEA=mRNA /GEN=DKFZp434I1916 /PROD=hypothetical protein /DB_XREF=gi:12053058 /UG=Hs.5881 ELL gene (11-19 lysine-rich leukemia gene) /FL=gb:AL136771.1 gb:NM_006532.1 gb:U16282.1 AL136771 elongation factor RNA polymerase II ELL 8178 NM_006532 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0008023 // transcription elongation factor complex // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 204097_s_at AF078865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078865.1 /DEF=Homo sapiens RNA-binding protein mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein /DB_XREF=gi:5531844 /UG=Hs.61184 CGI-79 protein /FL=gb:AF151837.1 gb:AF078865.1 gb:NM_016024.1 AF078865 RNA binding motif protein, X-linked 2 RBMX2 51634 NM_016024 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204098_at NM_016024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016024.1 /DEF=Homo sapiens CGI-79 protein (LOC51634), mRNA. /FEA=mRNA /GEN=LOC51634 /PROD=CGI-79 protein /DB_XREF=gi:7706315 /UG=Hs.61184 CGI-79 protein /FL=gb:AF151837.1 gb:AF078865.1 gb:NM_016024.1 NM_016024 RNA binding motif protein, X-linked 2 RBMX2 51634 NM_016024 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204099_at NM_003078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003078.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 (SMARCD3), mRNA. /FEA=mRNA /GEN=SMARCD3 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily d, member 3 /DB_XREF=gi:4507086 /UG=Hs.71622 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 /FL=gb:BC002628.1 gb:U66619.1 gb:NM_003078.1 NM_003078 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 SMARCD3 6604 NM_001003801 /// NM_001003802 /// NM_003078 0002052 // positive regulation of neuroblast proliferation // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003219 // cardiac right ventricle formation // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0016514 // SWI/SNF complex // non-traceable author statement /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction 204100_at NM_003250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003250.1 /DEF=Homo sapiens thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog) (THRA), mRNA. /FEA=mRNA /GEN=THRA /PROD=thyroid hormone receptor, alpha (avianerythroblastic leukemia viral (v-erb-a) oncogene homolog) /DB_XREF=gi:4507494 /UG=Hs.724 thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog) /FL=gb:BC000261.1 gb:BC002728.1 gb:NM_003250.1 gb:J03239.1 gb:M24899.1 NM_003250 thyroid hormone receptor, alpha THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 204101_at NM_000252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000252.1 /DEF=Homo sapiens myotubular myopathy 1 (MTM1), mRNA. /FEA=mRNA /GEN=MTM1 /PROD=myotubularin /DB_XREF=gi:4557895 /UG=Hs.75302 myotubular myopathy 1 /FL=gb:U46024.1 gb:NM_000252.1 NM_000252 myotubularin 1 MTM1 4534 NM_000252 /// XM_005274687 /// XM_006724820 /// XM_006724821 /// XM_006724822 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044088 // regulation of vacuole organization // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045109 // intermediate filament organization // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0048311 // mitochondrion distribution // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from direct assay 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031674 // I band // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0052629 // phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity // inferred from direct assay 204102_s_at NM_001961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001961.1 /DEF=Homo sapiens eukaryotic translation elongation factor 2 (EEF2), mRNA. /FEA=mRNA /GEN=EEF2 /PROD=eukaryotic translation elongation factor 2 /DB_XREF=gi:4503482 /UG=Hs.75309 eukaryotic translation elongation factor 2 /FL=gb:NM_001961.1 NM_001961 eukaryotic translation elongation factor 2 EEF2 1938 NM_001961 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008494 // translation activator activity // inferred from genetic interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204103_at NM_002984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002984.1 /DEF=Homo sapiens small inducible cytokine A4 (homologous to mouse Mip-1b) (SCYA4), mRNA. /FEA=mRNA /GEN=SCYA4 /PROD=small inducible cytokine A4 (homologous to mouseMip-1b) /DB_XREF=gi:4506844 /UG=Hs.75703 small inducible cytokine A4 (homologous to mouse Mip-1b) /FL=gb:J04130.1 gb:NM_002984.1 gb:M23502.1 gb:M25316.1 NM_002984 chemokine (C-C motif) ligand 4 CCL4 6351 NM_002984 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0050850 // positive regulation of calcium-mediated signaling // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204104_at NM_003083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003083.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 2, 45kD (SNAPC2), mRNA. /FEA=mRNA /GEN=SNAPC2 /PROD=small nuclear RNA activating complex,polypeptide 2, 45kD /DB_XREF=gi:4507102 /UG=Hs.78403 small nuclear RNA activating complex, polypeptide 2, 45kD /FL=gb:U44755.1 gb:U44898.1 gb:NM_003083.1 NM_003083 small nuclear RNA activating complex, polypeptide 2, 45kDa SNAPC2 6618 NM_003083 /// NR_030717 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 204105_s_at NM_005010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005010.1 /DEF=Homo sapiens neuronal cell adhesion molecule (NRCAM), mRNA. /FEA=mRNA /GEN=NRCAM /PROD=neuronal cell adhesion molecule /DB_XREF=gi:4826863 /UG=Hs.7912 neuronal cell adhesion molecule /FL=gb:AB002341.1 gb:NM_005010.1 NM_005010 neuronal cell adhesion molecule NRCAM 4897 NM_001037132 /// NM_001037133 /// NM_001193582 /// NM_001193583 /// NM_001193584 /// NM_005010 /// XM_005250373 /// XM_005250380 /// XM_005250383 /// XM_005250385 /// XM_006716003 /// XM_006716004 /// XM_006716005 /// XM_006716006 /// XM_006716007 /// XM_006716008 /// XM_006716009 /// XM_006716010 /// XM_006716011 /// XM_006716012 /// XM_006716013 /// XM_006716014 /// XR_428177 /// XR_428178 0001525 // angiogenesis // inferred from expression pattern /// 0001764 // neuron migration // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // non-traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0030516 // regulation of axon extension // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0045162 // clustering of voltage-gated sodium channels // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation 204106_at NM_006285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006285.1 /DEF=Homo sapiens testis-specific kinase 1 (TESK1), mRNA. /FEA=mRNA /GEN=TESK1 /PROD=testis-specific protein kinase 1 /DB_XREF=gi:5454109 /UG=Hs.79358 testis-specific kinase 1 /FL=gb:D50863.1 gb:NM_006285.1 NM_006285 testis-specific kinase 1 TESK1 7016 NM_006285 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204107_at BF445142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF445142 /FEA=EST /DB_XREF=gi:11510203 /DB_XREF=est:nad21b05.x1 /CLONE=IMAGE:3366081 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1 BF445142 nuclear transcription factor Y, alpha NFYA 4800 NM_002505 /// NM_021705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204108_at AL031778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031778 /DEF=Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine... /FEA=mRNA_5 /DB_XREF=gi:4153958 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1 AL031778 nuclear transcription factor Y, alpha NFYA 4800 NM_002505 /// NM_021705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204109_s_at NM_002505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002505.2 /DEF=Homo sapiens nuclear transcription factor Y, alpha (NFYA), transcript variant 1, mRNA. /FEA=mRNA /GEN=NFYA /PROD=nuclear transcription factor Y, alpha, isoform1 /DB_XREF=gi:11496975 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1 NM_002505 nuclear transcription factor Y, alpha NFYA 4800 NM_002505 /// NM_021705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204110_at U08092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U08092.1 /DEF=Human histamine N-methyltransferase (HNMT) mRNA, complete cds. /FEA=mRNA /GEN=HNMT /PROD=histamine N-methyltransferase /DB_XREF=gi:468258 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1 U08092 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204111_at N40285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N40285 /FEA=EST /DB_XREF=gi:1163830 /DB_XREF=est:yx80c01.r1 /CLONE=IMAGE:268032 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1 N40285 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204112_s_at NM_006895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006895.1 /DEF=Homo sapiens histamine N-methyltransferase (HNMT), mRNA. /FEA=mRNA /GEN=HNMT /PROD=histamine N-methyltransferase /DB_XREF=gi:5901969 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1 NM_006895 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204113_at NM_006560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006560.1 /DEF=Homo sapiens CUG triplet repeat, RNA-binding protein 1 (CUGBP1), mRNA. /FEA=mRNA /GEN=CUGBP1 /PROD=CUG triplet repeat, RNA-binding protein 1 /DB_XREF=gi:5729793 /UG=Hs.81248 CUG triplet repeat, RNA-binding protein 1 /FL=gb:U63289.1 gb:NM_006560.1 gb:AF267533.1 gb:AF267534.1 NM_006560 CUGBP, Elav-like family member 1 CELF1 10658 NM_001025596 /// NM_001172639 /// NM_001172640 /// NM_006560 /// NM_198700 /// XM_005252754 /// XM_005252755 /// XM_005252756 /// XM_006718122 /// XM_006718123 /// XM_006718124 /// XM_006718125 /// XM_006718126 /// XM_006718127 /// XM_006718128 /// XM_006718129 /// XM_006718130 /// XM_006718131 0006376 // mRNA splice site selection // inferred from sequence or structural similarity /// 0006397 // mRNA processing // traceable author statement /// 0007281 // germ cell development // non-traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016246 // RNA interference // non-traceable author statement /// 0017148 // negative regulation of translation // non-traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0042835 // BRE binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 204114_at NM_007361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007361.1 /DEF=Homo sapiens nidogen 2 (NID2), mRNA. /FEA=mRNA /GEN=NID2 /PROD=nidogen 2 /DB_XREF=gi:6679055 /UG=Hs.82733 nidogen 2 /FL=gb:D86425.1 gb:NM_007361.1 NM_007361 nidogen 2 (osteonidogen) NID2 22795 NM_007361 /// XM_005267405 /// XM_005267406 /// XM_005267407 /// XM_006720079 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement 204115_at NM_004126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004126.1 /DEF=Homo sapiens guanine nucleotide binding protein 11 (GNG11), mRNA. /FEA=mRNA /GEN=GNG11 /PROD=guanine nucleotide binding protein 11 /DB_XREF=gi:4758447 /UG=Hs.83381 guanine nucleotide binding protein 11 /FL=gb:NM_004126.1 gb:U31384.1 NM_004126 guanine nucleotide binding protein (G protein), gamma 11 GNG11 2791 NM_004126 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 204116_at NM_000206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000206.1 /DEF=Homo sapiens interleukin 2 receptor, gamma (severe combined immunodeficiency) (IL2RG), mRNA. /FEA=mRNA /GEN=IL2RG /PROD=interleukin 2 receptor, gamma chain, precursor /DB_XREF=gi:4557881 /UG=Hs.84 interleukin 2 receptor, gamma (severe combined immunodeficiency) /FL=gb:NM_000206.1 NM_000206 interleukin 2 receptor, gamma IL2RG 3561 NM_000206 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // traceable author statement /// 0038110 // interleukin-2-mediated signaling pathway // traceable author statement /// 0038111 // interleukin-7-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004911 // interleukin-2 receptor activity // traceable author statement /// 0004913 // interleukin-4 receptor activity // traceable author statement /// 0004917 // interleukin-7 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019976 // interleukin-2 binding // inferred from sequence or structural similarity /// 0019982 // interleukin-7 binding // inferred from electronic annotation 204117_at NM_002726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002726.1 /DEF=Homo sapiens prolyl endopeptidase (PREP), mRNA. /FEA=mRNA /GEN=PREP /PROD=prolyl endopeptidase /DB_XREF=gi:4506042 /UG=Hs.86978 prolyl endopeptidase /FL=gb:AB028867.1 gb:NM_002726.1 gb:AB020018.1 gb:D21102.1 NM_002726 prolyl endopeptidase PREP 5550 NM_002726 /// XM_005267044 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 204118_at NM_001778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001778.1 /DEF=Homo sapiens CD48 antigen (B-cell membrane protein) (CD48), mRNA. /FEA=mRNA /GEN=CD48 /PROD=CD48 antigen (B-cell membrane protein) /DB_XREF=gi:4502674 /UG=Hs.901 CD48 antigen (B-cell membrane protein) /FL=gb:M59904.1 gb:M37766.1 gb:NM_001778.1 NM_001778 CD48 molecule CD48 962 NM_001256030 /// NM_001778 /// XM_005245625 /// XM_006711640 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204119_s_at U90339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90339.1 /DEF=Human adenosine kinase short form mRNA, complete cds. /FEA=mRNA /PROD=adenosine kinase short form /DB_XREF=gi:1906010 /UG=Hs.94382 adenosine kinase /FL=gb:U50196.1 gb:BC003568.1 gb:U90339.1 gb:NM_001123.1 U90339 adenosine kinase ADK 132 NM_001123 /// NM_001202449 /// NM_001202450 /// NM_006721 /// XM_005269538 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006175 // dATP biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004001 // adenosine kinase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204120_s_at NM_001123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001123.1 /DEF=Homo sapiens adenosine kinase (ADK), transcript variant ADK-short, mRNA. /FEA=mRNA /GEN=ADK /PROD=adenosine kinase, isoform a /DB_XREF=gi:4501942 /UG=Hs.94382 adenosine kinase /FL=gb:U50196.1 gb:BC003568.1 gb:U90339.1 gb:NM_001123.1 NM_001123 adenosine kinase ADK 132 NM_001123 /// NM_001202449 /// NM_001202450 /// NM_006721 /// XM_005269538 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006175 // dATP biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004001 // adenosine kinase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204121_at NM_006705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006705.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible, gamma (GADD45G), mRNA. /FEA=mRNA /GEN=GADD45G /PROD=growth arrest and DNA-damage-inducible, gamma /DB_XREF=gi:9790905 /UG=Hs.9701 growth arrest and DNA-damage-inducible, gamma /FL=gb:AF087883.1 gb:BC000465.1 gb:AF078078.1 gb:AF079806.1 gb:D83023.1 gb:NM_006705.2 NM_006705 growth arrest and DNA-damage-inducible, gamma GADD45G 10912 NM_006705 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204122_at NM_003332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003332.1 /DEF=Homo sapiens TYRO protein tyrosine kinase binding protein (TYROBP), mRNA. /FEA=mRNA /GEN=TYROBP /PROD=TYRO protein tyrosine kinase binding protein /DB_XREF=gi:4507754 /UG=Hs.9963 TYRO protein tyrosine kinase binding protein /FL=gb:AF019562.1 gb:NM_003332.1 NM_003332 TYRO protein tyrosine kinase binding protein TYROBP 7305 NM_001173514 /// NM_001173515 /// NM_003332 /// NM_198125 /// NR_033390 /// XM_006723350 0002281 // macrophage activation involved in immune response // inferred from electronic annotation /// 0002283 // neutrophil activation involved in immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 2001204 // regulation of osteoclast development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204123_at NM_013975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013975.1 /DEF=Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant alpha, mRNA. /FEA=mRNA /GEN=LIG3 /PROD=ligase III, DNA, ATP-dependent, isoform alpha /DB_XREF=gi:7710125 /UG=Hs.100299 ligase III, DNA, ATP-dependent /FL=gb:NM_013975.1 NM_013975 ligase III, DNA, ATP-dependent LIG3 3980 NM_002311 /// NM_013975 /// XM_005257970 /// XM_005257971 /// XM_006721896 0006260 // DNA replication // inferred from electronic annotation /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006288 // base-excision repair, DNA ligation // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // not recorded /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043504 // mitochondrial DNA repair // inferred from electronic annotation /// 0045910 // negative regulation of DNA recombination // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0005739 // mitochondrion // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003910 // DNA ligase (ATP) activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204124_at AF146796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF146796.1 /DEF=Homo sapiens sodium dependent phosphate transporter isoform NaPi-IIb mRNA, complete cds. /FEA=mRNA /PROD=sodium dependent phosphate transporter isoformNaPi-IIb /DB_XREF=gi:6910977 /UG=Hs.105039 solute carrier family 34 (sodium phosphate), member 2 /FL=gb:AF111856.1 gb:NM_006424.1 gb:AF146796.1 AF146796 solute carrier family 34 (type II sodium/phosphate contransporter), member 2 SLC34A2 10568 NM_001177998 /// NM_001177999 /// NM_006424 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009750 // response to fructose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031528 // microvillus membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from direct assay /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 204125_at NM_016013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016013.1 /DEF=Homo sapiens CGI-65 protein (LOC51103), mRNA. /FEA=mRNA /GEN=LOC51103 /PROD=CGI-65 protein /DB_XREF=gi:7705778 /UG=Hs.106529 CGI-65 protein /FL=gb:BC000780.1 gb:AF151823.1 gb:NM_016013.1 NM_016013 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 NDUFAF1 51103 NM_016013 /// NR_045620 /// XM_006720555 /// XM_006720556 /// XM_006720557 /// XM_006720558 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006461 // protein complex assembly // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 204126_s_at NM_003504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003504.1 /DEF=Homo sapiens CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like (CDC45L), mRNA. /FEA=mRNA /GEN=CDC45L /PROD=CDC45 (cell division cycle 45, S.cerevisiae,homolog)-like /DB_XREF=gi:4502712 /UG=Hs.114311 CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like /FL=gb:AF053074.1 gb:AF062495.1 gb:AF081535.1 gb:NM_003504.1 NM_003504 cell division cycle 45 CDC45 8318 NM_001178010 /// NM_001178011 /// NM_003504 /// XM_005261285 /// XM_005261286 0000076 // DNA replication checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204127_at BC000149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000149.2 /DEF=Homo sapiens, replication factor C (activator 1) 3 (38kD), clone MGC:5276, mRNA, complete cds. /FEA=mRNA /PROD=replication factor C (activator 1) 3 (38kD) /DB_XREF=gi:12803002 /UG=Hs.115474 replication factor C (activator 1) 3 (38kD) /FL=gb:BC000149.2 gb:L07541.1 gb:NM_002915.1 BC000149 replication factor C (activator 1) 3, 38kDa RFC3 5983 NM_002915 /// NM_181558 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0046683 // response to organophosphorus // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003689 // DNA clamp loader activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204128_s_at NM_002915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002915.1 /DEF=Homo sapiens replication factor C (activator 1) 3 (38kD) (RFC3), mRNA. /FEA=mRNA /GEN=RFC3 /PROD=replication factor C (activator 1) 3 (38kD) /DB_XREF=gi:4506488 /UG=Hs.115474 replication factor C (activator 1) 3 (38kD) /FL=gb:BC000149.2 gb:L07541.1 gb:NM_002915.1 NM_002915 replication factor C (activator 1) 3, 38kDa RFC3 5983 NM_002915 /// NM_181558 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0046683 // response to organophosphorus // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003689 // DNA clamp loader activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204129_at NM_004326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004326.1 /DEF=Homo sapiens B-cell CLLlymphoma 9 (BCL9), mRNA. /FEA=mRNA /GEN=BCL9 /PROD=B-cell CLLlymphoma 9 /DB_XREF=gi:4757845 /UG=Hs.122607 B-cell CLLlymphoma 9 /FL=gb:NM_004326.1 NM_004326 B-cell CLL/lymphoma 9 BCL9 607 NM_004326 /// XM_005272971 /// XM_005277417 /// XM_005277418 /// XM_006711483 0014908 // myotube differentiation involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation 204130_at NM_000196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000196.1 /DEF=Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2), mRNA. /FEA=mRNA /GEN=HSD11B2 /PROD=hydroxysteroid (11-beta) dehydrogenase 2 /DB_XREF=gi:4504498 /UG=Hs.1376 hydroxysteroid (11-beta) dehydrogenase 2 /FL=gb:U26726.1 gb:U14631.1 gb:NM_000196.1 NM_000196 hydroxysteroid (11-beta) dehydrogenase 2 HSD11B2 3291 NM_000196 0001666 // response to hypoxia // inferred from electronic annotation /// 0002017 // regulation of blood volume by renal aldosterone // inferred from electronic annotation /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003845 // 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 204131_s_at N25732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25732 /FEA=EST /DB_XREF=gi:1140080 /DB_XREF=est:yx83c03.s1 /CLONE=IMAGE:268324 /UG=Hs.14845 forkhead box O3A /FL=gb:AF032886.1 gb:NM_001455.1 N25732 forkhead box O3 FOXO3 2309 NM_001455 /// NM_201559 /// XM_005266867 /// XM_005266868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay 204132_s_at NM_001455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001455.1 /DEF=Homo sapiens forkhead box O3A (FOXO3A), mRNA. /FEA=mRNA /GEN=FOXO3A /PROD=forkhead box O3A /DB_XREF=gi:4503738 /UG=Hs.14845 forkhead box O3A /FL=gb:AF032886.1 gb:NM_001455.1 NM_001455 forkhead box O3 /// forkhead box O3B pseudogene FOXO3 /// FOXO3B 2309 /// 2310 NM_001455 /// NM_201559 /// NR_026718 /// XM_005266867 /// XM_005266868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay 204133_at NM_004704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004704.1 /DEF=Homo sapiens U3 snoRNP-associated 55-kDa protein (U3-55K), mRNA. /FEA=mRNA /GEN=U3-55K /PROD=U3 snoRNP-associated 55-kDa protein /DB_XREF=gi:4759275 /UG=Hs.153768 U3 snoRNP-associated 55-kDa protein /FL=gb:BC001113.1 gb:NM_004704.1 NM_004704 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) RRP9 9136 NM_004704 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005732 // small nucleolar ribonucleoprotein complex // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204134_at NM_002599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002599.1 /DEF=Homo sapiens phosphodiesterase 2A, cGMP-stimulated (PDE2A), mRNA. /FEA=mRNA /GEN=PDE2A /PROD=phosphodiesterase 2A, cGMP-stimulated /DB_XREF=gi:4505656 /UG=Hs.154437 phosphodiesterase 2A, cGMP-stimulated /FL=gb:U67733.1 gb:NM_002599.1 NM_002599 phosphodiesterase 2A, cGMP-stimulated PDE2A 5138 NM_001143839 /// NM_001146209 /// NM_001243784 /// NM_002599 /// XM_005274040 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from expression pattern /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from mutant phenotype /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from direct assay /// 0043116 // negative regulation of vascular permeability // inferred from mutant phenotype /// 0043117 // positive regulation of vascular permeability // inferred from mutant phenotype /// 0046069 // cGMP catabolic process // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from mutant phenotype /// 0030553 // cGMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from mutant phenotype /// 0030911 // TPR domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204135_at NM_014890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014890.1 /DEF=Homo sapiens downregulated in ovarian cancer 1 (DOC1), mRNA. /FEA=mRNA /GEN=DOC1 /PROD=downregulated in ovarian cancer 1 /DB_XREF=gi:7657036 /UG=Hs.15432 downregulated in ovarian cancer 1 /FL=gb:U53445.1 gb:NM_014890.1 NM_014890 filamin A interacting protein 1-like FILIP1L 11259 NM_001042459 /// NM_001282793 /// NM_001282794 /// NM_014890 /// NM_182909 /// XM_006713486 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // non-traceable author statement 204136_at NM_000094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000094.1 /DEF=Homo sapiens collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) (COL7A1), mRNA. /FEA=mRNA /GEN=COL7A1 /PROD=collagen, type VII, alpha 1 (epidermolysisbullosa, dystrophic, dominant and recessive) /DB_XREF=gi:4502960 /UG=Hs.1640 collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) /FL=gb:NM_000094.1 gb:L02870.1 NM_000094 collagen, type VII, alpha 1 COL7A1 1294 NM_000094 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005590 // collagen type VII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204137_at NM_003272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003272.1 /DEF=Homo sapiens transmembrane 7 superfamily member 1 (upregulated in kidney) (TM7SF1), mRNA. /FEA=mRNA /GEN=TM7SF1 /PROD=transmembrane 7 superfamily member 1(upregulated in kidney) /DB_XREF=gi:4507544 /UG=Hs.15791 transmembrane 7 superfamily member 1 (upregulated in kidney) /FL=gb:AF027826.1 gb:NM_003272.1 NM_003272 G protein-coupled receptor 137B GPR137B 7107 NM_003272 /// XM_005273244 /// XR_247039 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 204138_s_at AI762174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762174 /FEA=EST /DB_XREF=gi:5177841 /DB_XREF=est:wh90g05.x1 /CLONE=IMAGE:2388056 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) /FL=gb:M58297.1 gb:NM_003422.1 AI762174 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204139_x_at NM_003422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003422.1 /DEF=Homo sapiens zinc finger protein 42 (myeloid-specific retinoic acid- responsive) (ZNF42), mRNA. /FEA=mRNA /GEN=ZNF42 /PROD=zinc finger protein 42 (myeloid-specificretinoic acid- responsive) /DB_XREF=gi:4508024 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) /FL=gb:M58297.1 gb:NM_003422.1 NM_003422 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204140_at NM_003596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003596.1 /DEF=Homo sapiens tyrosylprotein sulfotransferase 1 (TPST1), mRNA. /FEA=mRNA /GEN=TPST1 /PROD=tyrosylprotein sulfotransferase 1 /DB_XREF=gi:4507664 /UG=Hs.17279 tyrosylprotein sulfotransferase 1 /FL=gb:AF038009.1 gb:NM_003596.1 NM_003596 tyrosylprotein sulfotransferase 1 TPST1 8460 NM_003596 /// XM_005250642 0006478 // peptidyl-tyrosine sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008476 // protein-tyrosine sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204141_at NM_001069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001069.1 /DEF=Homo sapiens tubulin, beta polypeptide (TUBB), mRNA. /FEA=mRNA /GEN=TUBB /PROD=tubulin, beta polypeptide /DB_XREF=gi:4507728 /UG=Hs.179661 tubulin, beta polypeptide /FL=gb:BC001194.1 gb:NM_001069.1 NM_001069 tubulin, beta 2A class IIa TUBB2A 7280 NM_001069 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 204142_at NM_017512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017512.1 /DEF=Homo sapiens rTS beta protein (HSRTSBETA), mRNA. /FEA=mRNA /GEN=HSRTSBETA /PROD=rTS beta protein /DB_XREF=gi:8923790 /UG=Hs.180433 rTS beta protein /FL=gb:BC001285.1 gb:NM_017512.1 NM_017512 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 204143_s_at NM_017512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017512.1 /DEF=Homo sapiens rTS beta protein (HSRTSBETA), mRNA. /FEA=mRNA /GEN=HSRTSBETA /PROD=rTS beta protein /DB_XREF=gi:8923790 /UG=Hs.180433 rTS beta protein /FL=gb:BC001285.1 gb:NM_017512.1 NM_017512 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 204144_s_at NM_004204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004204.1 /DEF=Homo sapiens phosphatidylinositol glycan, class Q (PIGQ), mRNA. /FEA=mRNA /GEN=PIGQ /PROD=phosphatidylinositol glycan, class Q /DB_XREF=gi:4758465 /UG=Hs.18079 phosphatidylinositol glycan, class Q /FL=gb:AF030177.1 gb:AB003723.1 gb:NM_004204.1 NM_004204 phosphatidylinositol glycan anchor biosynthesis, class Q PIGQ 9091 NM_004204 /// NM_148920 0005975 // carbohydrate metabolic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation 204145_at NM_004477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004477.1 /DEF=Homo sapiens FSHD region gene 1 (FRG1), mRNA. /FEA=mRNA /GEN=FRG1 /PROD=FSHD region gene 1 /DB_XREF=gi:4758403 /UG=Hs.203772 FSHD region gene 1 /FL=gb:L76159.1 gb:NM_004477.1 NM_004477 FSHD region gene 1 /// protein FRG1-like /// uncharacterized LOC101930278 /// protein FRG1-like FRG1 /// LOC100289097 /// LOC101930278 /// LOC101930531 2483 /// 100289097 /// 101930278 /// 101930531 NM_004477 /// XM_005262879 /// XM_005262880 /// XM_006714166 /// XM_006725445 /// XM_006725446 /// XM_006725447 /// XR_250590 /// XR_250603 /// XR_426484 /// XR_430284 /// XR_430390 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation 204146_at BE966146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966146 /FEA=EST /DB_XREF=gi:11771248 /DB_XREF=est:601660074R1 /CLONE=IMAGE:3905635 /UG=Hs.24596 RAD51-interacting protein /FL=gb:AF006259.1 gb:NM_006479.1 BE966146 RAD51 associated protein 1 RAD51AP1 10635 NM_001130862 /// NM_006479 /// XM_006718952 /// XM_006718953 /// XM_006718954 /// XM_006718955 0000724 // double-strand break repair via homologous recombination // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204147_s_at NM_007111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007111.1 /DEF=Homo sapiens transcription factor Dp-1 (TFDP1), mRNA. /FEA=mRNA /GEN=TFDP1 /PROD=transcription factor Dp-1 /DB_XREF=gi:6005899 /UG=Hs.279576 transcription factor Dp-1 /FL=gb:L23959.1 gb:NM_007111.1 NM_007111 transcription factor Dp-1 TFDP1 7027 NM_007111 /// NR_026580 /// XM_005268326 /// XM_005268327 /// XM_005268328 /// XM_005268330 /// XM_005268331 /// XM_006719977 /// XM_006719978 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 204148_s_at NM_012230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012230.1 /DEF=Homo sapiens POM (POM121 rat homolog) and ZP3 fusion protein (POMZP3), mRNA. /FEA=mRNA /GEN=POMZP3 /PROD=POM (POM121 rat homolog) and ZP3 fusion protein /DB_XREF=gi:6912599 /UG=Hs.296380 POM (POM121 rat homolog) and ZP3 fusion protein /FL=gb:U10099.1 gb:NM_012230.1 NM_012230 POM121 and ZP3 fusion /// zona pellucida glycoprotein 3 (sperm receptor) POMZP3 /// ZP3 7784 /// 22932 NM_001110354 /// NM_007155 /// NM_012230 /// NM_152992 0001809 // positive regulation of type IV hypersensitivity // inferred from sequence or structural similarity /// 0001825 // blastocyst formation // inferred from sequence or structural similarity /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002687 // positive regulation of leukocyte migration // inferred from sequence or structural similarity /// 0002922 // positive regulation of humoral immune response // inferred from direct assay /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from direct assay /// 0007339 // binding of sperm to zona pellucida // inferred from genetic interaction /// 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from sequence or structural similarity /// 0032504 // multicellular organism reproduction // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035803 // egg coat formation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity /// 0048599 // oocyte development // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from mutant phenotype /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from sequence or structural similarity /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 2000344 // positive regulation of acrosome reaction // inferred from direct assay /// 2000360 // negative regulation of binding of sperm to zona pellucida // inferred from direct assay /// 2000368 // positive regulation of acrosomal vesicle exocytosis // inferred from direct assay /// 2000368 // positive regulation of acrosomal vesicle exocytosis // inferred from mutant phenotype /// 2000386 // positive regulation of ovarian follicle development // inferred from sequence or structural similarity /// 2000388 // positive regulation of antral ovarian follicle growth // inferred from sequence or structural similarity 0001669 // acrosomal vesicle // inferred from sequence or structural similarity /// 0002081 // outer acrosomal membrane // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from direct assay /// 0032190 // acrosin binding // inferred from physical interaction 204149_s_at NM_000850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000850.1 /DEF=Homo sapiens glutathione S-transferase M4 (GSTM4), mRNA. /FEA=mRNA /GEN=GSTM4 /PROD=glutathione S-transferase M4 /DB_XREF=gi:4504178 /UG=Hs.301961 glutathione S-transferase M4 /FL=gb:M96234.1 gb:NM_000850.1 NM_000850 glutathione S-transferase mu 4 GSTM4 2948 NM_000850 /// NM_147148 /// NM_147149 /// NR_024538 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 204150_at NM_015136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015136.1 /DEF=Homo sapiens KIAA0246 protein (KIAA0246), mRNA. /FEA=mRNA /GEN=KIAA0246 /PROD=KIAA0246 protein /DB_XREF=gi:12225239 /UG=Hs.301989 KIAA0246 protein /FL=gb:NM_015136.1 NM_015136 stabilin 1 STAB1 23166 NM_015136 /// XM_005264973 /// XM_005264974 /// XM_005264975 /// XM_006713065 /// XM_006713066 /// XR_427261 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from direct assay /// 0055114 // oxidation-reduction process // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // non-traceable author statement /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay 204151_x_at NM_001353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001353.2 /DEF=Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), mRNA. /FEA=mRNA /GEN=AKR1C1 /PROD=aldo-keto reductase family 1, member C1(dihydrodiol dehydrogenase 1; 20-alpha(3-alpha)-hydroxysteroid dehydrogenase) /DB_XREF=gi:5453542 /UG=Hs.306098 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) /FL=gb:U05684.1 gb:NM_001353.2 gb:M86609.1 NM_001353 aldo-keto reductase family 1, member C1 AKR1C1 1645 NM_001353 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation 204152_s_at AI738965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738965 /FEA=EST /DB_XREF=gi:5100946 /DB_XREF=est:wi12e11.x1 /CLONE=IMAGE:2390060 /UG=Hs.31939 manic fringe (Drosophila) homolog /FL=gb:U94352.1 gb:NM_002405.1 AI738965 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase MFNG 4242 NM_001166343 /// NM_002405 /// NR_029413 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204153_s_at NM_002405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002405.1 /DEF=Homo sapiens manic fringe (Drosophila) homolog (MFNG), mRNA. /FEA=mRNA /GEN=MFNG /PROD=manic fringe (Drosophila) homolog /DB_XREF=gi:4505158 /UG=Hs.31939 manic fringe (Drosophila) homolog /FL=gb:U94352.1 gb:NM_002405.1 NM_002405 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase MFNG 4242 NM_001166343 /// NM_002405 /// NR_029413 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204154_at NM_001801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001801.1 /DEF=Homo sapiens cysteine dioxygenase, type I (CDO1), mRNA. /FEA=mRNA /GEN=CDO1 /PROD=cysteine dioxygenase, type I /DB_XREF=gi:4502754 /UG=Hs.3229 cysteine dioxygenase, type I /FL=gb:D85777.1 gb:NM_001801.1 NM_001801 cysteine dioxygenase type 1 CDO1 1036 NM_001801 /// XR_427700 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000097 // sulfur amino acid biosynthetic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006534 // cysteine metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0019448 // L-cysteine catabolic process // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042412 // taurine biosynthetic process // inferred from electronic annotation /// 0042412 // taurine biosynthetic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046439 // L-cysteine metabolic process // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005829 // cytosol // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017172 // cysteine dioxygenase activity // inferred from sequence or structural similarity /// 0017172 // cysteine dioxygenase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047800 // cysteamine dioxygenase activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 204155_s_at AA044154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA044154 /FEA=EST /DB_XREF=gi:1522030 /DB_XREF=est:zk50b06.r1 /CLONE=IMAGE:486227 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1 AA044154 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204156_at AA044154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA044154 /FEA=EST /DB_XREF=gi:1522030 /DB_XREF=est:zk50b06.r1 /CLONE=IMAGE:486227 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1 AA044154 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204157_s_at NM_025164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025164.1 /DEF=Homo sapiens KIAA0999 protein (KIAA0999), mRNA. /FEA=mRNA /GEN=KIAA0999 /PROD=hypothetical protein FLJ12240 /DB_XREF=gi:13386467 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1 NM_025164 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204158_s_at NM_006019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006019.1 /DEF=Homo sapiens T-cell, immune regulator 1 (TCIRG1), mRNA. /FEA=mRNA /GEN=TCIRG1 /PROD=ATPase, H+ transporting, 116kD /DB_XREF=gi:5174620 /UG=Hs.46465 T-cell, immune regulator 1 /FL=gb:U45285.1 gb:NM_006019.1 NM_006019 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 TCIRG1 10312 NM_006019 /// NM_006053 /// XM_005273709 /// XM_005273710 /// XM_006718417 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 204159_at NM_001262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001262.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), mRNA. /FEA=mRNA /GEN=CDKN2C /PROD=cyclin-dependent kinase inhibitor 2C (p18,inhibits CDK4) /DB_XREF=gi:4502750 /UG=Hs.4854 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) /FL=gb:AF041248.1 gb:NM_001262.1 NM_001262 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) CDKN2C 1031 NM_001262 /// NM_078626 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 204160_s_at AW194947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194947 /FEA=EST /DB_XREF=gi:6473915 /DB_XREF=est:xn32e06.x1 /CLONE=IMAGE:2695426 /UG=Hs.54037 ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) /FL=gb:AB020686.1 gb:NM_014936.1 AW194947 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) ENPP4 22875 NM_014936 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0046130 // purine ribonucleoside catabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047710 // bis(5'-adenosyl)-triphosphatase activity // inferred from direct assay 204161_s_at NM_014936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014936.1 /DEF=Homo sapiens ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) (ENPP4), mRNA. /FEA=mRNA /GEN=ENPP4 /PROD=ectonucleotide pyrophosphatasephosphodiesterase4 (putative function) /DB_XREF=gi:7662357 /UG=Hs.54037 ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) /FL=gb:AB020686.1 gb:NM_014936.1 NM_014936 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) ENPP4 22875 NM_014936 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0046130 // purine ribonucleoside catabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047710 // bis(5'-adenosyl)-triphosphatase activity // inferred from direct assay 204162_at NM_006101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006101.1 /DEF=Homo sapiens highly expressed in cancer, rich in leucine heptad repeats (HEC), mRNA. /FEA=mRNA /GEN=HEC /PROD=highly expressed in cancer, rich in leucineheptad repeats /DB_XREF=gi:5174456 /UG=Hs.58169 highly expressed in cancer, rich in leucine heptad repeats /FL=gb:AF017790.1 gb:NM_006101.1 NM_006101 NDC80 kinetochore complex component NDC80 10403 NM_006101 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // traceable author statement /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000942 // condensed nuclear chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031262 // Ndc80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204163_at NM_007046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007046.1 /DEF=Homo sapiens elastin microfibril interface located protein (EMILIN), mRNA. /FEA=mRNA /GEN=EMILIN /PROD=elastin microfibril interface located protein /DB_XREF=gi:5901943 /UG=Hs.63348 elastin microfibril interface located protein /FL=gb:AF088916.1 gb:NM_007046.1 NM_007046 elastin microfibril interfacer 1 EMILIN1 11117 NM_007046 /// XM_006711928 0007155 // cell adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204164_at NM_006747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006747.1 /DEF=Homo sapiens signal-induced proliferation-associated gene 1 (SIPA1), mRNA. /FEA=mRNA /GEN=SIPA1 /PROD=signal-induced proliferation-associated gene 1 /DB_XREF=gi:5803168 /UG=Hs.7019 signal-induced proliferation-associated gene 1 /FL=gb:AB005666.1 gb:AF029789.1 gb:NM_006747.1 NM_006747 signal-induced proliferation-associated 1 SIPA1 6494 NM_006747 /// NM_153253 /// XM_005274189 /// XR_247210 0007010 // cytoskeleton organization // non-traceable author statement /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0032854 // positive regulation of Rap GTPase activity // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0046582 // Rap GTPase activator activity // non-traceable author statement 204165_at NM_003931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003931.1 /DEF=Homo sapiens WAS protein family, member 1 (WASF1), mRNA. /FEA=mRNA /GEN=WASF1 /PROD=WAS protein family, member 1 /DB_XREF=gi:4507912 /UG=Hs.75850 WAS protein family, member 1 /FL=gb:D87459.1 gb:NM_003931.1 gb:AF134303.1 NM_003931 WAS protein family, member 1 WASF1 8936 NM_001024934 /// NM_001024935 /// NM_001024936 /// NM_003931 /// XM_005267203 /// XM_005267204 /// XM_005267205 /// XM_005267206 /// XM_005267207 /// XM_005267208 /// XM_006715595 0006461 // protein complex assembly // non-traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // traceable author statement /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from mutant phenotype /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from mutant phenotype /// 0048365 // Rac GTPase binding // inferred from mutant phenotype 204166_at NM_014963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014963.1 /DEF=Homo sapiens KIAA0963 protein (KIAA0963), mRNA. /FEA=mRNA /GEN=KIAA0963 /PROD=KIAA0963 protein /DB_XREF=gi:7662409 /UG=Hs.7724 KIAA0963 protein /FL=gb:AB023180.1 gb:NM_014963.1 NM_014963 strawberry notch homolog 2 (Drosophila) SBNO2 22904 NM_001100122 /// NM_014963 /// XM_005259519 /// XM_005259520 0002281 // macrophage activation involved in immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype 204167_at NM_000060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000060.1 /DEF=Homo sapiens biotinidase (BTD), mRNA. /FEA=mRNA /GEN=BTD /PROD=biotinidase precursor /DB_XREF=gi:4557372 /UG=Hs.78885 biotinidase /FL=gb:NM_000060.1 gb:U03274.1 NM_000060 biotinidase BTD 686 NM_000060 /// NM_001281723 /// NM_001281724 /// NM_001281725 /// NM_001281726 /// XM_005265417 /// XM_006713314 /// XM_006713315 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004075 // biotin carboxylase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0047708 // biotinidase activity // inferred from electronic annotation 204168_at NM_002413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002413.1 /DEF=Homo sapiens microsomal glutathione S-transferase 2 (MGST2), mRNA. /FEA=mRNA /GEN=MGST2 /PROD=microsomal glutathione S-transferase 2 /DB_XREF=gi:4505180 /UG=Hs.81874 microsomal glutathione S-transferase 2 /FL=gb:U77604.1 gb:NM_002413.1 NM_002413 microsomal glutathione S-transferase 2 MGST2 4258 NM_001204366 /// NM_001204367 /// NM_001204368 /// NM_002413 /// XM_006714221 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // not recorded /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005635 // nuclear envelope // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004464 // leukotriene-C4 synthase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // not recorded /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204169_at NM_000883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000883.1 /DEF=Homo sapiens IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), mRNA. /FEA=mRNA /GEN=IMPDH1 /PROD=IMP (inosine monophosphate) dehydrogenase 1 /DB_XREF=gi:4504686 /UG=Hs.850 IMP (inosine monophosphate) dehydrogenase 1 /FL=gb:J05272.1 gb:NM_000883.1 NM_000883 IMP (inosine 5'-monophosphate) dehydrogenase 1 IMPDH1 3614 NM_000883 /// NM_001102605 /// NM_001142573 /// NM_001142574 /// NM_001142575 /// NM_001142576 /// NM_183243 /// XM_005250313 /// XM_005250314 /// XM_006715967 /// XM_006715968 /// XM_006715969 /// XM_006715970 /// XM_006715971 /// XM_006715972 /// XM_006715973 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006177 // GMP biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003938 // IMP dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018580 // nitronate monooxygenase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204170_s_at NM_001827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001827.1 /DEF=Homo sapiens CDC28 protein kinase 2 (CKS2), mRNA. /FEA=mRNA /GEN=CKS2 /PROD=CDC28 protein kinase 2 /DB_XREF=gi:4502858 /UG=Hs.83758 CDC28 protein kinase 2 /FL=gb:NM_001827.1 NM_001827 CDC28 protein kinase regulatory subunit 2 CKS2 1164 NM_001827 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation 204171_at NM_003161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003161.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 70kD, polypeptide 1 (RPS6KB1), mRNA. /FEA=mRNA /GEN=RPS6KB1 /PROD=serinethreonine kinase 14 alpha /DB_XREF=gi:4506736 /UG=Hs.86858 ribosomal protein S6 kinase, 70kD, polypeptide 1 /FL=gb:M60724.1 gb:NM_003161.1 NM_003161 ribosomal protein S6 kinase, 70kDa, polypeptide 1 RPS6KB1 6198 NM_001272042 /// NM_001272043 /// NM_001272044 /// NM_001272060 /// NM_003161 /// XM_006722009 /// XM_006722010 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0014878 // response to electrical stimulus involved in regulation of muscle adaptation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 204172_at NM_000097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000097.1 /DEF=Homo sapiens coproporphyrinogen oxidase (coproporphyria, harderoporphyria) (CPO), mRNA. /FEA=mRNA /GEN=CPO /PROD=coproporphyrinogen oxidase (coproporphyria,harderoporphyria) /DB_XREF=gi:4503016 /UG=Hs.89866 coproporphyrinogen oxidase (coproporphyria, harderoporphyria) /FL=gb:NM_000097.1 gb:D16611.1 NM_000097 coproporphyrinogen oxidase CPOX 1371 NM_000097 /// XM_005247125 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement 0004109 // coproporphyrinogen oxidase activity // traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 204173_at NM_002475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002475.1 /DEF=Homo sapiens myosin, light polypeptide 1, alkali; skeletal, fast (MYL1), mRNA. /FEA=mRNA /GEN=MYL1 /PROD=myosin, light polypeptide 1, alkali; skeletal,fast /DB_XREF=gi:4505302 /UG=Hs.90318 myosin, light polypeptide 1, alkali; skeletal, fast /FL=gb:M31211.1 gb:NM_002475.1 NM_002475 myosin, light chain 6B, alkali, smooth muscle and non-muscle MYL6B 140465 NM_001199629 /// NM_002475 0006936 // muscle contraction // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // traceable author statement 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 204174_at NM_001629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001629.1 /DEF=Homo sapiens arachidonate 5-lipoxygenase-activating protein (ALOX5AP), mRNA. /FEA=mRNA /GEN=ALOX5AP /PROD=arachidonate 5-lipoxygenase-activating protein /DB_XREF=gi:4502058 /UG=Hs.100194 arachidonate 5-lipoxygenase-activating protein /FL=gb:NM_001629.1 NM_001629 arachidonate 5-lipoxygenase-activating protein ALOX5AP 241 NM_001204406 /// NM_001629 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070207 // protein homotrimerization // inferred from physical interaction /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004364 // glutathione transferase activity // not recorded /// 0004464 // leukotriene-C4 synthase activity // not recorded /// 0004602 // glutathione peroxidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050544 // arachidonic acid binding // inferred from direct assay 204175_at NM_015871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015871.1 /DEF=Homo sapiens zinc finger protein (LOC51042), mRNA. /FEA=mRNA /GEN=LOC51042 /PROD=zinc finger protein /DB_XREF=gi:7705661 /UG=Hs.102419 zinc finger protein /FL=gb:BC002580.1 gb:D45213.1 gb:NM_015871.1 NM_015871 zinc finger protein 593 ZNF593 51042 NM_015871 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204176_at AA808694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA808694 /FEA=EST /DB_XREF=gi:2878100 /DB_XREF=est:oa47b08.s1 /CLONE=IMAGE:1308087 /UG=Hs.106290 Kelch motif containing protein /FL=gb:NM_014458.2 gb:AB026190.1 AA808694 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 204177_s_at NM_014458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014458.2 /DEF=Homo sapiens Kelch motif containing protein (AB026190), mRNA. /FEA=mRNA /GEN=AB026190 /PROD=Kelch motif containing protein /DB_XREF=gi:13677223 /UG=Hs.106290 Kelch motif containing protein /FL=gb:NM_014458.2 gb:AB026190.1 NM_014458 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 204178_s_at NM_006328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006328.1 /DEF=Homo sapiens RNA binding motif protein 14 (RBM14), mRNA. /FEA=mRNA /GEN=RBM14 /PROD=RNA binding motif protein 14 /DB_XREF=gi:5454063 /UG=Hs.11170 RNA binding motif protein 14 /FL=gb:AF080561.1 gb:NM_006328.1 NM_006328 RNA binding motif protein 14 RBM14 10432 NM_001198836 /// NM_001198837 /// NM_006328 /// NM_032886 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0009725 // response to hormone // traceable author statement /// 0016575 // histone deacetylation // inferred from physical interaction /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0016592 // mediator complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 204179_at NM_005368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005368.1 /DEF=Homo sapiens myoglobin (MB), mRNA. /FEA=mRNA /GEN=MB /PROD=myoglobin /DB_XREF=gi:4885476 /UG=Hs.118836 myoglobin /FL=gb:NM_005368.1 NM_005368 myoglobin MB 4151 NM_005368 /// NM_203377 /// NM_203378 /// XM_005261605 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0015671 // oxygen transport // inferred from electronic annotation /// 0031444 // slow-twitch skeletal muscle fiber contraction // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204180_s_at AI745225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI745225 /FEA=EST /DB_XREF=gi:5113513 /DB_XREF=est:wg10d12.x1 /CLONE=IMAGE:2364695 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1 AI745225 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204181_s_at T90308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T90308 /FEA=EST /DB_XREF=gi:718821 /DB_XREF=est:ye16a03.s1 /CLONE=IMAGE:117868 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1 T90308 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204182_s_at NM_014007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014007.1 /DEF=Homo sapiens KIAA0414 protein (KIAA0414), mRNA. /FEA=mRNA /GEN=KIAA0414 /PROD=KIAA0414 protein /DB_XREF=gi:7662099 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1 NM_014007 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204183_s_at AI478542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478542 /FEA=EST /DB_XREF=gi:4371768 /DB_XREF=est:tm53c11.x1 /CLONE=IMAGE:2161844 /UG=Hs.13944 adrenergic, beta, receptor kinase 2 /FL=gb:NM_005160.2 AI478542 adrenergic, beta, receptor kinase 2 ADRBK2 157 NM_005160 /// XM_006724158 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 204184_s_at NM_005160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005160.2 /DEF=Homo sapiens adrenergic, beta, receptor kinase 2 (ADRBK2), mRNA. /FEA=mRNA /GEN=ADRBK2 /PROD=beta adrenergic receptor kinase 2 /DB_XREF=gi:6138972 /UG=Hs.13944 adrenergic, beta, receptor kinase 2 /FL=gb:NM_005160.2 NM_005160 adrenergic, beta, receptor kinase 2 ADRBK2 157 NM_005160 /// XM_006724158 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 204185_x_at NM_005038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005038.1 /DEF=Homo sapiens peptidylprolyl isomerase D (cyclophilin D) (PPID), mRNA. /FEA=mRNA /GEN=PPID /PROD=peptidylprolyl isomerase D (cyclophilin D) /DB_XREF=gi:4826931 /UG=Hs.143482 peptidylprolyl isomerase D (cyclophilin D) /FL=gb:L11667.1 gb:NM_005038.1 NM_005038 peptidylprolyl isomerase D PPID 5481 NM_005038 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019076 // viral release from host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0030544 // Hsp70 protein binding // inferred from sequence or structural similarity /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 204186_s_at AI014573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI014573 /FEA=EST /DB_XREF=gi:3228954 /DB_XREF=est:ou40h11.x1 /CLONE=IMAGE:1628805 /UG=Hs.143482 peptidylprolyl isomerase D (cyclophilin D) /FL=gb:L11667.1 gb:NM_005038.1 AI014573 peptidylprolyl isomerase D PPID 5481 NM_005038 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019076 // viral release from host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0030544 // Hsp70 protein binding // inferred from sequence or structural similarity /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 204187_at NM_006877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006877.1 /DEF=Homo sapiens guanosine monophosphate reductase (GMPR), mRNA. /FEA=mRNA /GEN=GMPR /PROD=guanosine monophosphate reductase /DB_XREF=gi:11321610 /UG=Hs.1435 guanosine monophosphate reductase /FL=gb:NM_006877.1 gb:M24470.1 NM_006877 guanosine monophosphate reductase GMPR 2766 NM_006877 0006144 // purine nucleobase metabolic process // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 1902560 // GMP reductase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003920 // GMP reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204188_s_at M57707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57707.1 /DEF=Human retinoic acid receptor gamma mRNA, complete cds. /FEA=mRNA /GEN=RARG /PROD=retinoic acid receptor-gamma /DB_XREF=gi:190867 /UG=Hs.1497 retinoic acid receptor, gamma /FL=gb:M24857.1 gb:M57707.1 gb:M38258.1 gb:NM_000966.1 M57707 retinoic acid receptor, gamma RARG 5916 NM_000966 /// NM_001042728 /// NM_001243730 /// NM_001243731 /// NM_001243732 /// XM_005269054 /// XM_005269055 /// XM_005269056 /// XM_005269057 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0003430 // growth plate cartilage chondrocyte growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // traceable author statement /// 0060173 // limb development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060429 // epithelium development // inferred from electronic annotation /// 0060534 // trachea cartilage development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070384 // Harderian gland development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity 204189_at NM_000966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000966.1 /DEF=Homo sapiens retinoic acid receptor, gamma (RARG), mRNA. /FEA=mRNA /GEN=RARG /PROD=retinoic acid receptor, gamma /DB_XREF=gi:4506422 /UG=Hs.1497 retinoic acid receptor, gamma /FL=gb:M24857.1 gb:M57707.1 gb:M38258.1 gb:NM_000966.1 NM_000966 retinoic acid receptor, gamma RARG 5916 NM_000966 /// NM_001042728 /// NM_001243730 /// NM_001243731 /// NM_001243732 /// XM_005269054 /// XM_005269055 /// XM_005269056 /// XM_005269057 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0003430 // growth plate cartilage chondrocyte growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // traceable author statement /// 0060173 // limb development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060429 // epithelium development // inferred from electronic annotation /// 0060534 // trachea cartilage development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070384 // Harderian gland development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity 204190_at NM_005800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005800.1 /DEF=Homo sapiens highly charged protein (D13S106E), mRNA. /FEA=mRNA /GEN=D13S106E /PROD=highly charged protein /DB_XREF=gi:5031648 /UG=Hs.151236 highly charged protein /FL=gb:NM_005800.1 NM_005800 ubiquitin specific peptidase like 1 USPL1 10208 NM_005800 /// XM_005266213 /// XM_005266214 /// XM_006719751 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016926 // protein desumoylation // inferred from direct assay /// 0030576 // Cajal body organization // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032183 // SUMO binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0070140 // SUMO-specific isopeptidase activity // inferred from direct assay 204191_at NM_000629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000629.1 /DEF=Homo sapiens interferon (alpha, beta and omega) receptor 1 (IFNAR1), mRNA. /FEA=mRNA /GEN=IFNAR1 /PROD=interferon (alpha, beta and omega) receptor 1 /DB_XREF=gi:10835182 /UG=Hs.1513 interferon (alpha, beta and omega) receptor 1 /FL=gb:NM_000629.1 gb:J03171.1 NM_000629 interferon (alpha, beta and omega) receptor 1 IFNAR1 3454 NM_000629 /// XM_005260964 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004904 // interferon receptor activity // inferred from electronic annotation /// 0004905 // type I interferon receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204192_at NM_001774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001774.1 /DEF=Homo sapiens CD37 antigen (CD37), mRNA. /FEA=mRNA /GEN=CD37 /PROD=CD37 antigen /DB_XREF=gi:4502662 /UG=Hs.153053 CD37 antigen /FL=gb:NM_001774.1 NM_001774 CD37 molecule CD37 951 NM_001040031 /// NM_001774 /// XM_005259435 /// XM_005259436 /// XM_006723511 0001570 // vasculogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0002920 // regulation of humoral immune response // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030886 // negative regulation of myeloid dendritic cell activation // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204193_at NM_005198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005198.2 /DEF=Homo sapiens choline kinase-like (CHKL), mRNA. /FEA=mRNA /GEN=CHKL /PROD=choline kinase-like /DB_XREF=gi:6978648 /UG=Hs.154886 choline kinase-like /FL=gb:AB029886.1 gb:NM_005198.2 NM_005198 choline kinase beta CHKB 1120 NM_005198 /// NM_152253 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004095 // carnitine O-palmitoyltransferase activity // inferred from electronic annotation /// 0004095 // carnitine O-palmitoyltransferase activity // traceable author statement /// 0004103 // choline kinase activity // inferred from direct assay /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204194_at NM_001186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001186.1 /DEF=Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), mRNA. /FEA=mRNA /GEN=BACH1 /PROD=BTB and CNC homology 1, basic leucine zippertranscription factor 1 /DB_XREF=gi:4502352 /UG=Hs.154276 BTB and CNC homology 1, basic leucine zipper transcription factor 1 /FL=gb:AB002803.1 gb:NM_001186.1 NM_001186 BTB and CNC homology 1, basic leucine zipper transcription factor 1 BACH1 571 NM_001011545 /// NM_001186 /// NM_206866 /// NR_027655 /// XM_005261012 /// XM_005261013 /// XM_005261014 /// XM_006724034 /// XR_430352 /// XR_430353 /// XR_430354 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000117 // regulation of transcription involved in G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0020037 // heme binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204195_s_at AL570914 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL570914 /FEA=EST /DB_XREF=gi:12927687 /DB_XREF=est:AL570914 /CLONE=CS0DI013YK18 (3 prime) /UG=Hs.158225 PBXknotted 1 homeobox 1 /FL=gb:U68727.1 gb:NM_004571.1 AL570914 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204196_x_at NM_004571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004571.1 /DEF=Homo sapiens PBXknotted 1 hoemobox 1 (PKNOX1), mRNA. /FEA=mRNA /GEN=PKNOX1 /PROD=PBXknotted 1 hoemobox 1 /DB_XREF=gi:4758929 /UG=Hs.158225 PBXknotted 1 homeobox 1 /FL=gb:U68727.1 gb:NM_004571.1 NM_004571 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204197_s_at NM_004350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004350.1 /DEF=Homo sapiens runt-related transcription factor 3 (RUNX3), mRNA. /FEA=mRNA /GEN=RUNX3 /PROD=runt-related transcription factor 3 /DB_XREF=gi:4757917 /UG=Hs.170019 runt-related transcription factor 3 /FL=gb:NM_004350.1 NM_004350 runt-related transcription factor 3 RUNX3 864 NM_001031680 /// NM_004350 /// XM_005246024 /// XM_006711016 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007411 // axon guidance // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement 204198_s_at AA541630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA541630 /FEA=EST /DB_XREF=gi:2288064 /DB_XREF=est:ni99e01.s1 /CLONE=IMAGE:984984 /UG=Hs.170019 runt-related transcription factor 3 /FL=gb:NM_004350.1 AA541630 runt-related transcription factor 3 RUNX3 864 NM_001031680 /// NM_004350 /// XM_005246024 /// XM_006711016 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007411 // axon guidance // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement 204199_at NM_014636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014636.1 /DEF=Homo sapiens Ral guanine nucleotide exchange factor RalGPS1A (RalGPS1A), mRNA. /FEA=mRNA /GEN=RalGPS1A /PROD=Ral guanine nucleotide exchange factor RalGPS1A /DB_XREF=gi:7662069 /UG=Hs.170307 Ral guanine nucleotide exchange factor RalGPS1A /FL=gb:AB002349.1 gb:NM_014636.1 NM_014636 Ral GEF with PH domain and SH3 binding motif 1 RALGPS1 9649 NM_001190728 /// NM_001190729 /// NM_001190730 /// NM_014636 /// XM_005252318 /// XM_006717327 /// XM_006717328 /// XM_006717329 /// XM_006717330 /// XM_006717331 /// XM_006717332 /// XM_006717333 /// XM_006717334 /// XM_006717335 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032315 // regulation of Ral GTPase activity // inferred from direct assay /// 0032485 // regulation of Ral protein signal transduction // inferred from direct assay /// 0032852 // positive regulation of Ral GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008321 // Ral guanyl-nucleotide exchange factor activity // inferred from direct assay 204200_s_at NM_002608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002608.1 /DEF=Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (PDGFB), mRNA. /FEA=mRNA /GEN=PDGFB /PROD=platelet-derived growth factor beta polypeptide(simian sarcoma viral (v-sis) oncogene homolog) /DB_XREF=gi:4505680 /UG=Hs.1976 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) /FL=gb:M12783.1 gb:NM_002608.1 NM_002608 platelet-derived growth factor beta polypeptide PDGFB 5155 NM_002608 /// NM_033016 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009611 // response to wounding // non-traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038001 // paracrine signaling // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072255 // metanephric glomerular mesangial cell development // inferred from sequence or structural similarity /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072264 // metanephric glomerular endothelium development // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay /// 2000591 // positive regulation of metanephric mesenchymal cell migration // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 204201_s_at NM_006264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006264.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 13 (APO-1CD95 (Fas)-associated phosphatase) (PTPN13), mRNA. /FEA=mRNA /GEN=PTPN13 /PROD=protein tyrosine phosphatase, non-receptor type13 (APO-1CD95 (Fas)-associated phosphatase) /DB_XREF=gi:5453991 /UG=Hs.211595 protein tyrosine phosphatase, non-receptor type 13 (APO-1CD95 (Fas)-associated phosphatase) /FL=gb:D21210.1 gb:NM_006264.1 NM_006264 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) PTPN13 5783 NM_006264 /// NM_080683 /// NM_080684 /// NM_080685 /// XM_005263167 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 204202_at NM_017604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017604.1 /DEF=Homo sapiens KIAA1023 protein (KIAA1023), mRNA. /FEA=mRNA /GEN=KIAA1023 /PROD=hypothetical protein DKFZp434I0118 /DB_XREF=gi:8922140 /UG=Hs.21361 KIAA1023 protein /FL=gb:NM_017604.1 NM_017604 IQ motif containing E IQCE 23288 NM_001100390 /// NM_001287499 /// NM_001287500 /// NM_001287501 /// NM_001287502 /// NM_152558 /// XM_006715676 /// XM_006715677 /// XR_242067 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204203_at NM_001806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001806.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), gamma (CEBPG), mRNA. /FEA=mRNA /GEN=CEBPG /PROD=CCAATenhancer binding protein gamma /DB_XREF=gi:4502768 /UG=Hs.2227 CCAATenhancer binding protein (CEBP), gamma /FL=gb:NM_001806.1 gb:U20240.1 NM_001806 CCAAT/enhancer binding protein (C/EBP), gamma CEBPG 1054 NM_001252296 /// NM_001806 0001889 // liver development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0016071 // mRNA metabolic process // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from sequence or structural similarity /// 0043388 // positive regulation of DNA binding // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045078 // positive regulation of interferon-gamma biosynthetic process // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 204204_at NM_001860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001860.1 /DEF=Homo sapiens solute carrier family 31 (copper transporters), member 2 (SLC31A2), mRNA. /FEA=mRNA /GEN=SLC31A2 /PROD=solute carrier family 31 (copper transporters),member 2 /DB_XREF=gi:4507016 /UG=Hs.24030 solute carrier family 31 (copper transporters), member 2 /FL=gb:U83461.1 gb:NM_001860.1 NM_001860 solute carrier family 31 (copper transporter), member 2 SLC31A2 1318 NM_001860 /// XM_006716951 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005375 // copper ion transmembrane transporter activity // inferred from electronic annotation 204205_at NM_021822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021822.1 /DEF=Homo sapiens phorbolin-like protein MDS019 (MDS019), mRNA. /FEA=mRNA /GEN=MDS019 /PROD=phorbolin-like protein MDS019 /DB_XREF=gi:13399303 /UG=Hs.250619 phorbolin-like protein MDS019 /FL=gb:AF182420.1 gb:NM_021822.1 NM_021822 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G APOBEC3G 60489 NM_021822 /// XM_006724290 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016553 // base conversion or substitution editing // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030895 // apolipoprotein B mRNA editing enzyme complex // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from direct assay 204206_at NM_020310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020310.1 /DEF=Homo sapiens MAX binding protein (MNT), mRNA. /FEA=mRNA /GEN=MNT /PROD=MAX binding protein /DB_XREF=gi:9945317 /UG=Hs.25497 MAX binding protein /FL=gb:NM_020310.1 NM_020310 MAX network transcriptional repressor MNT 4335 NM_020310 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 204207_s_at AB012142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012142.1 /DEF=Homo sapiens hCAP1a mRNA for mRNA capping enzyme, complete cds. /FEA=mRNA /GEN=hCAP1a /PROD=mRNA capping enzyme /DB_XREF=gi:2979495 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AF025654.1 gb:AB012142.1 gb:AB009022.1 gb:NM_003800.1 AB012142 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 204208_at NM_003800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003800.1 /DEF=Homo sapiens RNA guanylyltransferase and 5-phosphatase (RNGTT), mRNA. /FEA=mRNA /GEN=RNGTT /PROD=RNA guanylyltransferase and 5-phosphatase /DB_XREF=gi:4506562 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AF025654.1 gb:AB012142.1 gb:AB009022.1 gb:NM_003800.1 NM_003800 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 204209_at AI638771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI638771 /FEA=EST /DB_XREF=gi:4691005 /DB_XREF=est:tt32b06.x1 /CLONE=IMAGE:2242451 /UG=Hs.273558 phosphate cytidylyltransferase 1, choline, alpha isoform /FL=gb:NM_005017.1 gb:L28957.1 AI638771 phosphate cytidylyltransferase 1, choline, alpha PCYT1A 5130 NM_005017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from sequence or structural similarity /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204210_s_at NM_005017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005017.1 /DEF=Homo sapiens phosphate cytidylyltransferase 1, choline, alpha isoform (PCYT1A), mRNA. /FEA=mRNA /GEN=PCYT1A /PROD=phosphate cytidylyltransferase 1, choline, alphaisoform /DB_XREF=gi:4826887 /UG=Hs.273558 phosphate cytidylyltransferase 1, choline, alpha isoform /FL=gb:NM_005017.1 gb:L28957.1 NM_005017 phosphate cytidylyltransferase 1, choline, alpha PCYT1A 5130 NM_005017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from sequence or structural similarity /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204211_x_at NM_002759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002759.1 /DEF=Homo sapiens protein kinase, interferon-inducible double stranded RNA dependent (PRKR), mRNA. /FEA=mRNA /GEN=PRKR /PROD=protein kinase, interferon-inducible doublestranded RNA dependent /DB_XREF=gi:4506102 /UG=Hs.274382 protein kinase, interferon-inducible double stranded RNA dependent /FL=gb:M35663.1 gb:M85294.1 gb:NM_002759.1 NM_002759 eukaryotic translation initiation factor 2-alpha kinase 2 EIF2AK2 5610 NM_001135651 /// NM_001135652 /// NM_002759 0000186 // activation of MAPKK activity // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0030683 // evasion or tolerance by virus of host immune response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900225 // regulation of NLRP3 inflammasome complex assembly // inferred from sequence or structural similarity /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from sequence or structural similarity /// 1901532 // regulation of hematopoietic progenitor cell differentiation // inferred from sequence or structural similarity /// 1902033 // regulation of hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 1902036 // regulation of hematopoietic stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204212_at NM_005469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005469.1 /DEF=Homo sapiens peroxisomal acyl-CoA thioesterase (PTE1), mRNA. /FEA=mRNA /GEN=PTE1 /PROD=peroxisomal acyl-CoA thioesterase /DB_XREF=gi:4885564 /UG=Hs.283476 peroxisomal acyl-CoA thioesterase /FL=gb:AF014404.1 gb:AF124264.1 gb:NM_005469.1 NM_005469 acyl-CoA thioesterase 8 ACOT8 10005 NM_005469 /// NM_183385 /// NM_183386 /// XM_005260239 /// XM_005260240 /// XR_244130 0006637 // acyl-CoA metabolic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043649 // dicarboxylic acid catabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from mutant phenotype /// 0005782 // peroxisomal matrix // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033882 // choloyl-CoA hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay /// 0052815 // medium-chain acyl-CoA hydrolase activity // inferred from direct assay 204213_at NM_002644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002644.1 /DEF=Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA. /FEA=mRNA /GEN=PIGR /PROD=polymeric immunoglobulin receptor /DB_XREF=gi:11342673 /UG=Hs.288579 polymeric immunoglobulin receptor /FL=gb:NM_002644.1 NM_002644 polymeric immunoglobulin receptor PIGR 5284 NM_002644 /// XM_005273163 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002415 // immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0038093 // Fc receptor signaling pathway // inferred from direct assay /// 0043113 // receptor clustering // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001792 // polymeric immunoglobulin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 204214_s_at NM_006834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006834.1 /DEF=Homo sapiens RAB32, member RAS oncogene family (RAB32), mRNA. /FEA=mRNA /GEN=RAB32 /PROD=RAB32, member RAS oncogene family /DB_XREF=gi:5803132 /UG=Hs.32217 RAB32, member RAS oncogene family /FL=gb:U71127.1 gb:NM_006834.1 NM_006834 RAB32, member RAS oncogene family RAB32 10981 NM_006834 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0090382 // phagosome maturation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031905 // early endosome lumen // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from physical interaction /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay /// 0035650 // AP-1 adaptor complex binding // inferred from physical interaction /// 0035651 // AP-3 adaptor complex binding // inferred from physical interaction 204215_at NM_024315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024315.1 /DEF=Homo sapiens hypothetical protein MGC4175 (MGC4175), mRNA. /FEA=mRNA /GEN=MGC4175 /PROD=hypothetical protein MGC4175 /DB_XREF=gi:13236556 /UG=Hs.322404 hypothetical protein MGC4175 /FL=gb:BC002837.1 gb:NM_024315.1 NM_024315 transmembrane protein 243, mitochondrial TMEM243 79161 NM_024315 /// XM_005250585 /// XM_005250586 /// XM_005250587 /// XM_005250588 /// XM_005250589 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204216_s_at NM_024824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024824.1 /DEF=Homo sapiens hypothetical protein FLJ11806 (FLJ11806), mRNA. /FEA=mRNA /GEN=FLJ11806 /PROD=hypothetical protein FLJ11806 /DB_XREF=gi:13376221 /UG=Hs.323443 hypothetical protein FLJ11806 /FL=gb:NM_024824.1 NM_024824 zinc finger CCCH-type containing 14 ZC3H14 79882 NM_001160103 /// NM_001160104 /// NM_024824 /// NM_207660 /// NM_207661 /// NM_207662 /// XM_005268067 /// XM_005268068 /// XM_005268069 /// XM_005268070 /// XM_005268071 /// XM_005268073 /// XM_006720257 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204217_s_at NM_005619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005619.1 /DEF=Homo sapiens reticulon 2 (RTN2), mRNA. /FEA=mRNA /GEN=RTN2 /PROD=reticulon 2 /DB_XREF=gi:5032054 /UG=Hs.3803 reticulon 2 /FL=gb:AF004222.1 gb:AF004224.1 gb:NM_005619.1 NM_005619 reticulon 2 RTN2 6253 NM_005619 /// NM_206900 /// NM_206901 /// NM_206902 /// XR_243948 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0014802 // terminal cisterna // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0030315 // T-tubule // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204218_at NM_014042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014042.1 /DEF=Homo sapiens DKFZP564M082 protein (DKFZP564M082), mRNA. /FEA=mRNA /GEN=DKFZP564M082 /PROD=DKFZP564M082 protein /DB_XREF=gi:7661621 /UG=Hs.38044 DKFZP564M082 protein /FL=gb:BC005156.1 gb:BC005393.1 gb:AF077206.1 gb:AL080071.1 gb:NM_014042.1 NM_014042 anaphase promoting complex subunit 15 ANAPC15 25906 NM_001278485 /// NM_001278486 /// NM_001278487 /// NM_001278488 /// NM_001278489 /// NM_001278490 /// NM_001278491 /// NM_001278492 /// NM_001278493 /// NM_001278494 /// NM_014042 /// XM_005273885 /// XM_005273886 /// XM_005273887 /// XM_005273888 /// XM_006718492 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005680 // anaphase-promoting complex // inferred from direct assay 204219_s_at NM_002802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002802.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 1 (PSMC1), mRNA. /FEA=mRNA /GEN=PSMC1 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 1 /DB_XREF=gi:4506206 /UG=Hs.4745 proteasome (prosome, macropain) 26S subunit, ATPase, 1 /FL=gb:L02426.1 gb:NM_002802.1 NM_002802 proteasome (prosome, macropain) 26S subunit, ATPase, 1 PSMC1 5700 NM_002802 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204220_at NM_004877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004877.1 /DEF=Homo sapiens glia maturation factor, gamma (GMFG), mRNA. /FEA=mRNA /GEN=GMFG /PROD=glia maturation factor, gamma /DB_XREF=gi:4758439 /UG=Hs.5210 glia maturation factor, gamma /FL=gb:AB001993.1 gb:AF038956.1 gb:NM_004877.1 NM_004877 glia maturation factor, gamma GMFG 9535 NM_004877 /// XM_005259440 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 204221_x_at U16307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16307.1 /DEF=Human glioma pathogenesis-related protein (GliPR) mRNA, complete cds. /FEA=mRNA /GEN=GliPR /PROD=glioma pathogenesis-related protein /DB_XREF=gi:1100927 /UG=Hs.64639 glioma pathogenesis-related protein /FL=gb:U16307.1 gb:NM_006851.1 U16307 GLI pathogenesis-related 1 GLIPR1 11010 NM_006851 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204222_s_at NM_006851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006851.1 /DEF=Homo sapiens glioma pathogenesis-related protein (RTVP1), mRNA. /FEA=mRNA /GEN=RTVP1 /PROD=glioma pathogenesis-related protein /DB_XREF=gi:5803150 /UG=Hs.64639 glioma pathogenesis-related protein /FL=gb:U16307.1 gb:NM_006851.1 NM_006851 GLI pathogenesis-related 1 GLIPR1 11010 NM_006851 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204223_at NM_002725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002725.1 /DEF=Homo sapiens proline arginine-rich end leucine-rich repeat protein (PRELP), mRNA. /FEA=mRNA /GEN=PRELP /PROD=proline arginine-rich end leucine-rich repeatprotein /DB_XREF=gi:4506040 /UG=Hs.76494 proline arginine-rich end leucine-rich repeat protein /FL=gb:NM_002725.1 gb:U29089.1 NM_002725 proline/arginine-rich end leucine-rich repeat protein PRELP 5549 NM_002725 /// NM_201348 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 204224_s_at NM_000161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000161.1 /DEF=Homo sapiens GTP cyclohydrolase 1 (dopa-responsive dystonia) (GCH1), mRNA. /FEA=mRNA /GEN=GCH1 /PROD=GTP cyclohydrolase 1 (dopa-responsive dystonia) /DB_XREF=gi:4503948 /UG=Hs.86724 GTP cyclohydrolase 1 (dopa-responsive dystonia) /FL=gb:NM_000161.1 gb:U66097.1 gb:U19523.1 NM_000161 GTP cyclohydrolase 1 GCH1 2643 NM_000161 /// NM_001024024 /// NM_001024070 /// NM_001024071 /// XM_005267530 0006184 // GTP catabolic process // inferred from direct assay /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from direct assay /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from mutant phenotype /// 0006809 // nitric oxide biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035998 // 7,8-dihydroneopterin 3'-triphosphate biosynthetic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from direct assay /// 0042559 // pteridine-containing compound biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0050884 // neuromuscular process controlling posture // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0051066 // dihydrobiopterin metabolic process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003934 // GTP cyclohydrolase I activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 204225_at NM_006037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006037.2 /DEF=Homo sapiens histone deacetylase 4 (HDAC4), mRNA. /FEA=mRNA /GEN=HDAC4 /PROD=histone deacetylase 4 /DB_XREF=gi:13259519 /UG=Hs.91400 histone deacetylase 4 /FL=gb:NM_006037.2 gb:AF132607.1 NM_006037 histone deacetylase 4 HDAC4 9759 NM_006037 /// XM_006712877 /// XM_006712878 /// XM_006712879 /// XM_006712880 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from electronic annotation /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0030183 // B cell differentiation // traceable author statement /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0034983 // peptidyl-lysine deacetylation // inferred from direct assay /// 0042113 // B cell activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051153 // regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001047 // core promoter binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from direct assay /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 204226_at NM_014393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014393.1 /DEF=Homo sapiens staufen (Drosophila, RNA-binding protein) homolog 2 (STAU2), mRNA. /FEA=mRNA /GEN=STAU2 /PROD=staufen homolog 2 /DB_XREF=gi:7657624 /UG=Hs.96870 staufen (Drosophila, RNA-binding protein) homolog 2 /FL=gb:NM_014393.1 NM_014393 staufen double-stranded RNA binding protein 2 STAU2 27067 NM_001164380 /// NM_001164381 /// NM_001164382 /// NM_001164383 /// NM_001164384 /// NM_001164385 /// NM_014393 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204227_s_at NM_004614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004614.1 /DEF=Homo sapiens thymidine kinase 2, mitochondrial (TK2), mRNA. /FEA=mRNA /GEN=TK2 /PROD=thymidine kinase 2, mitochondrial /DB_XREF=gi:10281329 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1 NM_004614 thymidine kinase 2, mitochondrial TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204228_at NM_006347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006347.1 /DEF=Homo sapiens cyclophilin (USA-CYP), mRNA. /FEA=mRNA /GEN=USA-CYP /PROD=cyclophilin /DB_XREF=gi:5454153 /UG=Hs.9880 peptidyl prolyl isomerase H (cyclophilin H) /FL=gb:BC003412.1 gb:AF016371.1 gb:AF036331.1 gb:NM_006347.1 NM_006347 peptidylprolyl isomerase H (cyclophilin H) PPIH 10465 NM_006347 /// XM_005270362 /// XM_005270364 /// XM_005270366 /// XM_006710293 /// XR_426585 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071001 // U4/U6 snRNP // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 204229_at H40895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H40895 /FEA=EST /DB_XREF=gi:916947 /DB_XREF=est:yn93f01.s1 /CLONE=IMAGE:175993 /UG=Hs.6535 brain-specific Na-dependent inorganic phosphate cotransporter /FL=gb:AB032436.1 gb:NM_020309.1 H40895 solute carrier family 17 (vesicular glutamate transporter), member 7 SLC17A7 57030 NM_020309 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0042137 // sequestering of neurotransmitter // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015319 // sodium:inorganic phosphate symporter activity // inferred from direct assay /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from electronic annotation 204230_s_at NM_020309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020309.1 /DEF=Homo sapiens brain-specific Na-dependent inorganic phosphate cotransporter (BNPI), mRNA. /FEA=mRNA /GEN=BNPI /PROD=brain-specific Na-dependent inorganic phosphatecotransporter /DB_XREF=gi:9945321 /UG=Hs.6535 brain-specific Na-dependent inorganic phosphate cotransporter /FL=gb:AB032436.1 gb:NM_020309.1 NM_020309 solute carrier family 17 (vesicular glutamate transporter), member 7 SLC17A7 57030 NM_020309 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0042137 // sequestering of neurotransmitter // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015319 // sodium:inorganic phosphate symporter activity // inferred from direct assay /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from electronic annotation 204231_s_at NM_001441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001441.1 /DEF=Homo sapiens fatty acid amide hydrolase (FAAH), mRNA. /FEA=mRNA /GEN=FAAH /PROD=fatty acid amide hydrolase /DB_XREF=gi:4557574 /UG=Hs.326190 fatty acid amide hydrolase /FL=gb:U82535.1 gb:NM_001441.1 NM_001441 fatty acid amide hydrolase FAAH 2166 NM_001441 0008152 // metabolic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from sequence or structural similarity 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0017064 // fatty acid amide hydrolase activity // inferred from direct assay /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation 204232_at NM_004106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004106.1 /DEF=Homo sapiens Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide (FCER1G), mRNA. /FEA=mRNA /GEN=FCER1G /PROD=Fc fragment of IgE, high affinity I, receptorfor, gamma polypeptide precursor /DB_XREF=gi:4758343 /UG=Hs.743 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide /FL=gb:M33195.1 gb:NM_004106.1 NM_004106 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide FCER1G 2207 NM_004106 0001798 // positive regulation of type IIa hypersensitivity // inferred from electronic annotation /// 0001805 // positive regulation of type III hypersensitivity // inferred from electronic annotation /// 0001812 // positive regulation of type I hypersensitivity // inferred from electronic annotation /// 0002283 // neutrophil activation involved in immune response // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0002554 // serotonin secretion by platelet // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010543 // regulation of platelet activation // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032765 // positive regulation of mast cell cytokine production // inferred from electronic annotation /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032998 // Fc-epsilon receptor I complex // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019767 // IgE receptor activity // inferred from electronic annotation /// 0019863 // IgE binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 204233_s_at AI991328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991328 /FEA=EST /DB_XREF=gi:5838233 /DB_XREF=est:wu42f05.x1 /CLONE=IMAGE:2522721 /UG=Hs.77221 choline kinase /FL=gb:NM_001277.1 AI991328 choline kinase alpha CHKA 1119 NM_001277 /// NM_212469 /// XR_428904 /// XR_428905 /// XR_428906 /// XR_428907 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019695 // choline metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004103 // choline kinase activity // inferred from direct assay /// 0004104 // cholinesterase activity // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0033265 // choline binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204234_s_at AI476267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI476267 /FEA=EST /DB_XREF=gi:4329312 /DB_XREF=est:ti72g01.x1 /CLONE=IMAGE:2137584 /UG=Hs.104382 zinc finger protein 195 /FL=gb:AF003540.1 gb:NM_007152.1 AI476267 zinc finger protein 195 ZNF195 7748 NM_001130519 /// NM_001130520 /// NM_001242841 /// NM_001242842 /// NM_001242843 /// NM_001256823 /// NM_001256824 /// NM_001256825 /// NM_007152 /// NR_040083 /// NR_046381 /// NR_046382 /// XM_006718306 /// XM_006718307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204235_s_at AF200715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF200715.1 /DEF=Homo sapiens PTB domain adaptor protein CED-6 mRNA, complete cds. /FEA=mRNA /PROD=PTB domain adaptor protein CED-6 /DB_XREF=gi:6409467 /UG=Hs.107056 CED-6 protein /FL=gb:AF200715.1 gb:AF191771.1 gb:NM_016315.1 AF200715 GULP, engulfment adaptor PTB domain containing 1 GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204236_at NM_002017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002017.2 /DEF=Homo sapiens Friend leukemia virus integration 1 (FLI1), mRNA. /FEA=mRNA /GEN=FLI1 /PROD=Friend leukemia virus integration 1 /DB_XREF=gi:7110592 /UG=Hs.108043 Friend leukemia virus integration 1 /FL=gb:BC001670.1 gb:M98833.3 gb:NM_002017.2 NM_002017 Fli-1 proto-oncogene, ETS transcription factor FLI1 2313 NM_001167681 /// NM_001271010 /// NM_001271012 /// NM_002017 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007599 // hemostasis // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204237_at NM_016315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016315.1 /DEF=Homo sapiens CED-6 protein (CED-6), mRNA. /FEA=mRNA /GEN=CED-6 /PROD=CED-6 protein /DB_XREF=gi:7705317 /UG=Hs.107056 CED-6 protein /FL=gb:AF200715.1 gb:AF191771.1 gb:NM_016315.1 NM_016315 GULP, engulfment adaptor PTB domain containing 1 GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204238_s_at NM_006443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006443.1 /DEF=Homo sapiens putative c-Myc-responsive (RCL), mRNA. /FEA=mRNA /GEN=RCL /PROD=putative c-Myc-responsive /DB_XREF=gi:5454001 /UG=Hs.109752 putative c-Myc-responsive /FL=gb:AF040105.1 gb:NM_006443.1 NM_006443 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 DNPH1 10591 NM_006443 /// NM_199184 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009159 // deoxyribonucleoside monophosphate catabolic process // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050144 // nucleoside deoxyribosyltransferase activity // inferred from electronic annotation /// 0070694 // deoxyribonucleoside 5'-monophosphate N-glycosidase activity // inferred from sequence or structural similarity 204239_s_at NM_005386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005386.1 /DEF=Homo sapiens neuronatin (NNAT), mRNA. /FEA=mRNA /GEN=NNAT /PROD=neuronatin /DB_XREF=gi:4885520 /UG=Hs.117546 neuronatin /FL=gb:U25033.1 gb:BC001768.1 gb:AB002392.1 gb:NM_005386.1 NM_005386 neuronatin NNAT 4826 NM_005386 /// NM_181689 0006810 // transport // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009249 // protein lipoylation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 204240_s_at NM_006444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006444.1 /DEF=Homo sapiens structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E (CAP-E), mRNA. /FEA=mRNA /GEN=CAP-E /PROD=structural maintenance of chromosomes (SMC)family member, chromosome-associated protein E /DB_XREF=gi:5453590 /UG=Hs.119023 SMC2 (structural maintenance of chromosomes 2, yeast)-like 1 /FL=gb:AF092563.1 gb:NM_006444.1 NM_006444 structural maintenance of chromosomes 2 SMC2 10592 NM_001042550 /// NM_001042551 /// NM_001265602 /// NM_006444 /// XM_006716933 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 204241_at BF055171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055171 /FEA=EST /DB_XREF=gi:10809067 /DB_XREF=est:7j75g12.x1 /CLONE=IMAGE:3392326 /UG=Hs.12773 acyl-Coenzyme A oxidase 3, pristanoyl /FL=gb:NM_003501.1 BF055171 acyl-CoA oxidase 3, pristanoyl ACOX3 8310 NM_001101667 /// NM_003501 /// XM_005248011 /// XM_005248012 /// XM_005248013 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016402 // pristanoyl-CoA oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204242_s_at NM_003501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003501.1 /DEF=Homo sapiens acyl-Coenzyme A oxidase 3, pristanoyl (ACOX3), mRNA. /FEA=mRNA /GEN=ACOX3 /PROD=acyl-Coenzyme A oxidase 3, pristanoyl /DB_XREF=gi:4501870 /UG=Hs.12773 acyl-Coenzyme A oxidase 3, pristanoyl /FL=gb:NM_003501.1 NM_003501 acyl-CoA oxidase 3, pristanoyl ACOX3 8310 NM_001101667 /// NM_003501 /// XM_005248011 /// XM_005248012 /// XM_005248013 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016402 // pristanoyl-CoA oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204243_at NM_012421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012421.1 /DEF=Homo sapiens rearranged L-myc fusion sequence (RLF), mRNA. /FEA=mRNA /GEN=RLF /PROD=rearranged L-myc fusion sequence /DB_XREF=gi:6912631 /UG=Hs.13321 rearranged L-myc fusion sequence /FL=gb:U22377.1 gb:NM_012421.1 NM_012421 rearranged L-myc fusion RLF 6018 NM_012421 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0009294 // DNA mediated transformation // non-traceable author statement /// 0015074 // DNA integration // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051276 // chromosome organization // inferred from direct assay /// 0051276 // chromosome organization // non-traceable author statement 0005634 // nucleus // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204244_s_at NM_006716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006716.1 /DEF=Homo sapiens activator of S phase kinase (ASK), mRNA. /FEA=mRNA /GEN=ASK /PROD=activator of S phase kinase /DB_XREF=gi:5729733 /UG=Hs.152759 activator of S phase kinase /FL=gb:AB028069.1 gb:AF160249.1 gb:AF160876.1 gb:NM_006716.1 NM_006716 DBF4 zinc finger DBF4 10926 NM_006716 /// XM_005250120 /// XM_005250121 /// XM_005250122 /// XM_006715843 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204245_s_at AW242755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242755 /FEA=EST /DB_XREF=gi:6576602 /DB_XREF=est:xm90f12.x1 /CLONE=IMAGE:2691503 /UG=Hs.155150 ribonuclease P (14kD) /FL=gb:AF001175.1 gb:NM_007042.1 AW242755 ribonuclease P/MRP 14kDa subunit RPP14 11102 NM_001098783 /// NM_007042 /// NR_049755 /// NR_049756 /// NR_049757 /// NR_049758 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204246_s_at NM_007234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007234.2 /DEF=Homo sapiens dynactin 3 (p22) (DCTN3), transcript variant 1, mRNA. /FEA=mRNA /GEN=DCTN3 /PROD=dynactin 3, isoform 1 /DB_XREF=gi:13259516 /UG=Hs.15961 dynactin 3 (p22) /FL=gb:NM_007234.2 gb:AF082513.1 NM_007234 dynactin 3 (p22) DCTN3 11258 NM_001281425 /// NM_001281426 /// NM_001281427 /// NM_007234 /// NM_024348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from direct assay /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from physical interaction /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204247_s_at NM_004935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004935.1 /DEF=Homo sapiens cyclin-dependent kinase 5 (CDK5), mRNA. /FEA=mRNA /GEN=CDK5 /PROD=cyclin-dependent kinase 5 /DB_XREF=gi:4826674 /UG=Hs.166071 cyclin-dependent kinase 5 /FL=gb:BC005115.1 gb:NM_004935.1 NM_004935 cyclin-dependent kinase 5 CDK5 1020 NM_001164410 /// NM_004935 0001764 // neuron migration // traceable author statement /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008306 // associative learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0021697 // cerebellar cortex formation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0031914 // negative regulation of synaptic plasticity // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032801 // receptor catabolic process // inferred from electronic annotation /// 0033136 // serine phosphorylation of STAT3 protein // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048675 // axon extension // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from electronic annotation /// 0071156 // regulation of cell cycle arrest // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 2000251 // positive regulation of actin cytoskeleton reorganization // traceable author statement /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016533 // cyclin-dependent protein kinase 5 holoenzyme complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005176 // ErbB-2 class receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030549 // acetylcholine receptor activator activity // inferred from sequence or structural similarity /// 0043125 // ErbB-3 class receptor binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity 204248_at NM_002067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002067.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (GNA11), mRNA. /FEA=mRNA /GEN=GNA11 /PROD=guanine nucleotide binding protein (G protein),alpha 11 (Gq class) /DB_XREF=gi:4504036 /UG=Hs.1686 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) /FL=gb:M69013.1 gb:AF011497.1 gb:NM_002067.1 NM_002067 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 204249_s_at NM_005574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005574.2 /DEF=Homo sapiens LIM domain only 2 (rhombotin-like 1) (LMO2), mRNA. /FEA=mRNA /GEN=LMO2 /PROD=LIM domain only 2 /DB_XREF=gi:6633806 /UG=Hs.184585 LIM domain only 2 (rhombotin-like 1) /FL=gb:NM_005574.2 NM_005574 LIM domain only 2 (rhombotin-like 1) LMO2 4005 NM_001142315 /// NM_001142316 /// NM_005574 /// XM_005252920 /// XM_005252921 /// XM_006718229 0007275 // multicellular organismal development // traceable author statement /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay 204250_s_at AI655714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655714 /FEA=EST /DB_XREF=gi:4739693 /DB_XREF=est:tt14f03.x1 /CLONE=IMAGE:2240765 /UG=Hs.18624 KIAA1052 protein /FL=gb:AB028975.1 gb:NM_014956.1 AI655714 centrosomal protein 164kDa CEP164 22897 NM_001271933 /// NM_014956 /// XM_005271452 /// XM_005271453 /// XM_005271454 /// XM_005271455 /// XM_005271456 /// XM_005271457 /// XM_005271458 /// XM_005271459 /// XM_005271460 /// XM_006718788 /// XM_006718789 /// XM_006718790 /// XM_006718791 /// XM_006718792 /// XM_006718793 /// XM_006718794 /// XR_428971 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0097539 // ciliary transition fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204251_s_at NM_014956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014956.1 /DEF=Homo sapiens KIAA1052 protein (KIAA1052), mRNA. /FEA=mRNA /GEN=KIAA1052 /PROD=KIAA1052 protein /DB_XREF=gi:7662463 /UG=Hs.18624 KIAA1052 protein /FL=gb:AB028975.1 gb:NM_014956.1 NM_014956 centrosomal protein 164kDa CEP164 22897 NM_001271933 /// NM_014956 /// XM_005271452 /// XM_005271453 /// XM_005271454 /// XM_005271455 /// XM_005271456 /// XM_005271457 /// XM_005271458 /// XM_005271459 /// XM_005271460 /// XM_006718788 /// XM_006718789 /// XM_006718790 /// XM_006718791 /// XM_006718792 /// XM_006718793 /// XM_006718794 /// XR_428971 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0097539 // ciliary transition fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204252_at M68520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M68520.1 /DEF=Human cdc2-related protein kinase mRNA, complete cds. /FEA=mRNA /PROD=cdc2-related protein kinase /DB_XREF=gi:180177 /UG=Hs.19192 cyclin-dependent kinase 2 /FL=gb:BC003065.1 gb:M68520.1 gb:NM_001798.1 M68520 cyclin-dependent kinase 2 CDK2 1017 NM_001290230 /// NM_001798 /// NM_052827 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031571 // mitotic G1 DNA damage checkpoint // traceable author statement /// 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051298 // centrosome duplication // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060968 // regulation of gene silencing // inferred from direct assay /// 0071732 // cellular response to nitric oxide // traceable author statement 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204253_s_at AA454701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA454701 /FEA=EST /DB_XREF=gi:2177477 /DB_XREF=est:zx76e01.s1 /CLONE=IMAGE:809688 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1 AA454701 vitamin D (1,25- dihydroxyvitamin D3) receptor VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204254_s_at NM_000376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000376.1 /DEF=Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), mRNA. /FEA=mRNA /GEN=VDR /PROD=vitamin D (1,25- dihydroxyvitamin D3) receptor /DB_XREF=gi:4507882 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1 NM_000376 vitamin D (1,25- dihydroxyvitamin D3) receptor VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204255_s_at AA772285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA772285 /FEA=EST /DB_XREF=gi:2824068 /DB_XREF=est:ai42d11.s1 /CLONE=1359669 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1 AA772285 vitamin D (1,25- dihydroxyvitamin D3) receptor VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204256_at NM_024090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024090.1 /DEF=Homo sapiens hypothetical protein MGC5487 (MGC5487), mRNA. /FEA=mRNA /GEN=MGC5487 /PROD=hypothetical protein MGC5487 /DB_XREF=gi:13129087 /UG=Hs.211556 hypothetical protein MGC5487 /FL=gb:NM_024090.1 NM_024090 ELOVL fatty acid elongase 6 ELOVL6 79071 NM_001130721 /// NM_024090 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030497 // fatty acid elongation // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042759 // long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 204257_at NM_021727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021727.1 /DEF=Homo sapiens fatty acid desaturase 3 (FADS3), mRNA. /FEA=mRNA /GEN=FADS3 /PROD=fatty acid desaturase 3 /DB_XREF=gi:13375615 /UG=Hs.21765 fatty acid desaturase 3 /FL=gb:AF084560.1 gb:NM_021727.1 gb:BC004901.1 gb:AF134404.1 NM_021727 fatty acid desaturase 3 FADS3 3995 NM_021727 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 204258_at NM_001270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001270.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 1 (CHD1), mRNA. /FEA=mRNA /GEN=CHD1 /PROD=chromodomain helicase DNA binding protein 1 /DB_XREF=gi:4557446 /UG=Hs.22670 chromodomain helicase DNA binding protein 1 /FL=gb:AF006513.1 gb:NM_001270.1 NM_001270 chromodomain helicase DNA binding protein 1 CHD1 1105 NM_001270 /// XM_005271866 /// XM_005271867 /// XR_427702 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 204259_at NM_002423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002423.2 /DEF=Homo sapiens matrix metalloproteinase 7 (matrilysin, uterine) (MMP7), mRNA. /FEA=mRNA /GEN=MMP7 /PROD=matrix metalloproteinase 7 preproprotein /DB_XREF=gi:13027804 /UG=Hs.2256 matrix metalloproteinase 7 (matrilysin, uterine) /FL=gb:NM_002423.2 gb:BC003635.1 NM_002423 matrix metallopeptidase 7 (matrilysin, uterine) MMP7 4316 NM_002423 0002779 // antibacterial peptide secretion // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204260_at NM_001819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001819.1 /DEF=Homo sapiens chromogranin B (secretogranin 1) (CHGB), mRNA. /FEA=mRNA /GEN=CHGB /PROD=chromogranin B precursor /DB_XREF=gi:4502806 /UG=Hs.2281 chromogranin B (secretogranin 1) /FL=gb:BC000375.1 gb:NM_001819.1 NM_001819 chromogranin B (secretogranin 1) CHGB 1114 NM_001819 0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204261_s_at AA716657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA716657 /FEA=EST /DB_XREF=gi:2728931 /DB_XREF=est:zg70h11.s1 /CLONE=IMAGE:398757 /UG=Hs.25363 presenilin 2 (Alzheimer disease 4) /FL=gb:NM_000447.1 gb:NM_012486.1 gb:L44577.1 gb:L43964.1 AA716657 presenilin 2 PSEN2 5664 NM_000447 /// NM_012486 /// XM_005273199 0001666 // response to hypoxia // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030426 // growth cone // not recorded /// 0031594 // neuromuscular junction // not recorded /// 0035253 // ciliary rootlet // not recorded /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004175 // endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204262_s_at NM_000447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000447.1 /DEF=Homo sapiens presenilin 2 (Alzheimer disease 4) (PSEN2), transcript variant 1, mRNA. /FEA=mRNA /GEN=PSEN2 /PROD=presenilin 2 isoform 1 /DB_XREF=gi:4506164 /UG=Hs.25363 presenilin 2 (Alzheimer disease 4) /FL=gb:NM_000447.1 gb:NM_012486.1 gb:L44577.1 gb:L43964.1 NM_000447 presenilin 2 PSEN2 5664 NM_000447 /// NM_012486 /// XM_005273199 0001666 // response to hypoxia // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030426 // growth cone // not recorded /// 0031594 // neuromuscular junction // not recorded /// 0035253 // ciliary rootlet // not recorded /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004175 // endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204263_s_at M58581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M58581.1 /DEF=Human carnitine palmitoyltransferase (CPT1) mRNA, complete cds. /FEA=mRNA /GEN=CPT1 /PROD=carnitine palmitoyltransferase /DB_XREF=gi:180988 /UG=Hs.274336 carnitine palmitoyltransferase II /FL=gb:U09648.1 gb:BC002445.1 gb:BC005172.1 gb:M58581.1 gb:NM_000098.1 M58581 carnitine palmitoyltransferase 2 CPT2 1376 NM_000098 /// XM_005270484 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 204264_at NM_000098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000098.1 /DEF=Homo sapiens carnitine palmitoyltransferase II (CPT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CPT2 /PROD=carnitine palmitoyltransferase II /DB_XREF=gi:4503022 /UG=Hs.274336 carnitine palmitoyltransferase II /FL=gb:U09648.1 gb:BC002445.1 gb:BC005172.1 gb:M58581.1 gb:NM_000098.1 NM_000098 carnitine palmitoyltransferase 2 CPT2 1376 NM_000098 /// XM_005270484 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 204265_s_at NM_022107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022107.1 /DEF=Homo sapiens G18.2 protein (G18.2), mRNA. /FEA=mRNA /GEN=G18.2 /PROD=G18.2 protein /DB_XREF=gi:11545816 /UG=Hs.288316 chromosome 6 open reading frame 9 /FL=gb:NM_022107.1 gb:AF155657.1 NM_022107 G-protein signaling modulator 3 GPSM3 63940 NM_001276501 /// NM_022107 0006955 // immune response // non-traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from electronic annotation 204266_s_at NM_001277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001277.1 /DEF=Homo sapiens choline kinase (CHK), mRNA. /FEA=mRNA /GEN=CHK /PROD=choline kinase /DB_XREF=gi:4557454 /UG=Hs.77221 choline kinase /FL=gb:NM_001277.1 NM_001277 choline kinase alpha CHKA 1119 NM_001277 /// NM_212469 /// XR_428904 /// XR_428905 /// XR_428906 /// XR_428907 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019695 // choline metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004103 // choline kinase activity // inferred from direct assay /// 0004104 // cholinesterase activity // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0033265 // choline binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204267_x_at NM_004203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004203.1 /DEF=Homo sapiens membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1), mRNA. /FEA=mRNA /GEN=PKMYT1 /PROD=membrane-associated tyrosine- andthreonine-specific cdc2-inhibitory kinase /DB_XREF=gi:4758927 /UG=Hs.77783 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase /FL=gb:U56816.1 gb:AF014118.1 gb:NM_004203.1 NM_004203 protein kinase, membrane associated tyrosine/threonine 1 PKMYT1 9088 NM_001258450 /// NM_001258451 /// NM_004203 /// NM_182687 /// XM_005255675 /// XM_006720976 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204268_at NM_005978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005978.2 /DEF=Homo sapiens S100 calcium-binding protein A2 (S100A2), mRNA. /FEA=mRNA /GEN=S100A2 /PROD=S100 calcium-binding protein A2 /DB_XREF=gi:9845513 /UG=Hs.38991 S100 calcium-binding protein A2 /FL=gb:BC002829.1 gb:NM_005978.2 NM_005978 S100 calcium binding protein A2 S100A2 6273 NM_005978 0043542 // endothelial cell migration // inferred from mutant phenotype 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204269_at NM_006875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006875.1 /DEF=Homo sapiens pim-2 oncogene (PIM2), mRNA. /FEA=mRNA /GEN=PIM2 /PROD=pim-2 oncogene /DB_XREF=gi:5803124 /UG=Hs.80205 pim-2 oncogene /FL=gb:U77735.1 gb:NM_006875.1 NM_006875 Pim-2 proto-oncogene, serine/threonine kinase PIM2 11040 NM_006875 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007140 // male meiosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204270_at AI568728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI568728 /FEA=EST /DB_XREF=gi:4532102 /DB_XREF=est:th15a06.x1 /CLONE=IMAGE:2118322 /UG=Hs.2969 v-ski avian sarcoma viral oncogene homolog /FL=gb:NM_003036.1 AI568728 SKI proto-oncogene SKI 6497 NM_003036 /// XM_005244775 /// XM_005244776 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009948 // anterior/posterior axis specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010626 // negative regulation of Schwann cell proliferation // inferred from genetic interaction /// 0014902 // myotube differentiation // inferred from direct assay /// 0021772 // olfactory bulb development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // non-traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from genetic interaction /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031064 // negative regulation of histone deacetylation // inferred from electronic annotation /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043585 // nose morphogenesis // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0048870 // cell motility // non-traceable author statement /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060325 // face morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0070207 // protein homotrimerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction /// 0046811 // histone deacetylase inhibitor activity // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 204271_s_at M74921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74921.1 /DEF=Human endothelin receptor mRNA, complete cds. /FEA=mRNA /GEN=ETs /PROD=endothelin receptor /DB_XREF=gi:182275 /UG=Hs.82002 endothelin receptor type B /FL=gb:M74921.1 gb:D90402.1 gb:NM_000115.1 M74921 endothelin receptor type B EDNRB 1910 NM_000115 /// NM_001122659 /// NM_001201397 /// NM_003991 /// NR_047024 /// XM_005266275 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014043 // negative regulation of neuron maturation // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014826 // vein smooth muscle contraction // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031620 // regulation of fever generation // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035645 // enteric smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from mutant phenotype /// 0048265 // response to pain // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from direct assay /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // inferred from direct assay /// 0004962 // endothelin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 204272_at NM_006149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006149.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 4 (galectin 4) (LGALS4), mRNA. /FEA=mRNA /GEN=LGALS4 /PROD=galectin 4 /DB_XREF=gi:6006017 /UG=Hs.5302 lectin, galactoside-binding, soluble, 4 (galectin 4) /FL=gb:BC003661.1 gb:BC005146.1 gb:AF014838.1 gb:AB006781.1 gb:U82953.1 gb:NM_006149.2 NM_006149 lectin, galactoside-binding, soluble, 4 LGALS4 3960 NM_006149 0007155 // cell adhesion // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 204273_at NM_000115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000115.1 /DEF=Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1, mRNA. /FEA=mRNA /GEN=EDNRB /PROD=endothelin receptor type B, isoform 1 /DB_XREF=gi:4557546 /UG=Hs.82002 endothelin receptor type B /FL=gb:M74921.1 gb:D90402.1 gb:NM_000115.1 NM_000115 endothelin receptor type B EDNRB 1910 NM_000115 /// NM_001122659 /// NM_001201397 /// NM_003991 /// NR_047024 /// XM_005266275 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014043 // negative regulation of neuron maturation // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014826 // vein smooth muscle contraction // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031620 // regulation of fever generation // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035645 // enteric smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from mutant phenotype /// 0048265 // response to pain // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from direct assay /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // inferred from direct assay /// 0004962 // endothelin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 204274_at AA812215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA812215 /FEA=EST /DB_XREF=gi:2881826 /DB_XREF=est:ob84g01.s1 /CLONE=IMAGE:1338096 /UG=Hs.9222 estrogen receptor binding site associated, antigen, 9 /FL=gb:BC005249.1 gb:AF006265.1 gb:AB007619.1 gb:NM_004215.1 AA812215 estrogen receptor binding site associated, antigen, 9 EBAG9 9166 NM_001278938 /// NM_004215 /// NM_198120 0001558 // regulation of cell growth // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016505 // peptidase activator activity involved in apoptotic process // non-traceable author statement 204275_at AI796687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796687 /FEA=EST /DB_XREF=gi:5362150 /DB_XREF=est:wh59f02.x1 /CLONE=IMAGE:2385051 /UG=Hs.55836 small optic lobes (Drosophila) homolog /FL=gb:U85647.1 gb:NM_005632.1 AI796687 calpain 15 CAPN15 6650 NM_005632 /// XM_005255514 /// XM_005255516 /// XM_005255517 /// XM_005255518 /// XM_006720931 /// XM_006720932 /// XM_006720933 /// XM_006720934 /// XM_006720935 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006508 // proteolysis // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // traceable author statement /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204276_at BE895437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE895437 /FEA=EST /DB_XREF=gi:10358829 /DB_XREF=est:601437912F1 /CLONE=IMAGE:3922971 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1 BE895437 thymidine kinase 2, mitochondrial TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204277_s_at BE895437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE895437 /FEA=EST /DB_XREF=gi:10358829 /DB_XREF=est:601437912F1 /CLONE=IMAGE:3922971 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1 BE895437 thymidine kinase 2, mitochondrial TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204278_s_at NM_004215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004215.1 /DEF=Homo sapiens estrogen receptor binding site associated, antigen, 9 (EBAG9), mRNA. /FEA=mRNA /GEN=EBAG9 /PROD=estrogen receptor binding site associated,antigen, 9 /DB_XREF=gi:4758229 /UG=Hs.9222 estrogen receptor binding site associated, antigen, 9 /FL=gb:BC005249.1 gb:AF006265.1 gb:AB007619.1 gb:NM_004215.1 NM_004215 estrogen receptor binding site associated, antigen, 9 EBAG9 9166 NM_001278938 /// NM_004215 /// NM_198120 0001558 // regulation of cell growth // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016505 // peptidase activator activity involved in apoptotic process // non-traceable author statement 204279_at NM_002800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002800.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) (PSMB9), mRNA. /FEA=mRNA /GEN=PSMB9 /PROD=proteasome (prosome, macropain) subunit, betatype, 9 (large multifunctional protease 2) /DB_XREF=gi:4506204 /UG=Hs.9280 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) /FL=gb:U01025.1 gb:NM_002800.1 NM_002800 proteasome (prosome, macropain) subunit, beta type, 9 PSMB9 5698 NM_002800 /// NM_148954 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204280_at NM_006480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006480.1 /DEF=Homo sapiens regulator of G-protein signalling 14 (RGS14), mRNA. /FEA=mRNA /GEN=RGS14 /PROD=regulator of G-protein signalling 14 /DB_XREF=gi:5454005 /UG=Hs.9347 regulator of G-protein signalling 14 /FL=gb:AF037195.1 gb:NM_006480.1 NM_006480 regulator of G-protein signaling 14 RGS14 10636 NM_006480 /// XM_005265794 /// XM_005265795 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from sequence or structural similarity /// 0031914 // negative regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from sequence or structural similarity /// 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation 204281_at NM_003213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003213.1 /DEF=Homo sapiens TEA domain family member 4 (TEAD4), mRNA. /FEA=mRNA /GEN=TEAD4 /PROD=TEA domain family member 4 /DB_XREF=gi:4507426 /UG=Hs.94865 TEA domain family member 4 /FL=gb:U63824.1 gb:NM_003213.1 NM_003213 TEA domain family member 4 TEAD4 7004 NM_003213 /// NM_201441 /// NM_201443 0001501 // skeletal system development // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0001830 // trophectodermal cell fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0035329 // hippo signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204282_s_at NM_006567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006567.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase (FARS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FARS1 /PROD=phenylalanine-tRNA synthetase /DB_XREF=gi:5729819 /UG=Hs.57969 phenylalanine-tRNA synthetase /FL=gb:AF097441.1 gb:NM_006567.1 NM_006567 phenylalanyl-tRNA synthetase 2, mitochondrial FARS2 10667 NM_006567 /// XM_005248811 /// XM_005248812 /// XM_005248813 /// XM_005248814 /// XM_006714966 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204283_at NM_006567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006567.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase (FARS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FARS1 /PROD=phenylalanine-tRNA synthetase /DB_XREF=gi:5729819 /UG=Hs.57969 phenylalanine-tRNA synthetase /FL=gb:AF097441.1 gb:NM_006567.1 NM_006567 phenylalanyl-tRNA synthetase 2, mitochondrial FARS2 10667 NM_006567 /// XM_005248811 /// XM_005248812 /// XM_005248813 /// XM_005248814 /// XM_006714966 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204284_at N26005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N26005 /FEA=EST /DB_XREF=gi:1140353 /DB_XREF=est:yx88f04.s1 /CLONE=IMAGE:268831 /UG=Hs.303090 protein phosphatase 1, regulatory (inhibitor) subunit 5 /FL=gb:NM_005398.1 N26005 protein phosphatase 1, regulatory subunit 3C PPP1R3C 5507 NM_005398 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation 204285_s_at AI857639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI857639 /FEA=EST /DB_XREF=gi:5511255 /DB_XREF=est:wk95g09.x1 /CLONE=IMAGE:2423200 /UG=Hs.96 phorbol-12-myristate-13-acetate-induced protein 1 /FL=gb:NM_021127.1 AI857639 phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 5366 NM_021127 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from direct assay /// 0010907 // positive regulation of glucose metabolic process // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043331 // response to dsRNA // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 204286_s_at NM_021127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021127.1 /DEF=Homo sapiens phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), mRNA. /FEA=mRNA /GEN=PMAIP1 /PROD=phorbol-12-myristate-13-acetate-induced protein1 /DB_XREF=gi:10863922 /UG=Hs.96 phorbol-12-myristate-13-acetate-induced protein 1 /FL=gb:NM_021127.1 NM_021127 phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 5366 NM_021127 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from direct assay /// 0010907 // positive regulation of glucose metabolic process // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043331 // response to dsRNA // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 204287_at NM_004711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004711.1 /DEF=Homo sapiens synaptogyrin 1 (SYNGR1), mRNA. /FEA=mRNA /GEN=SYNGR1 /PROD=synaptogyrin 1 /DB_XREF=gi:4759199 /UG=Hs.6139 synaptogyrin 1 /FL=gb:NM_004711.1 NM_004711 synaptogyrin 1 SYNGR1 9145 NM_004711 /// NM_145731 /// NM_145738 0006605 // protein targeting // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 204288_s_at NM_021069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021069.1 /DEF=Homo sapiens ArgAbl-interacting protein ArgBP2 (ARGBP2), transcript variant 2, mRNA. /FEA=mRNA /GEN=ARGBP2 /PROD=ArgAbl-interacting protein 2, isoform 2 /DB_XREF=gi:10947117 /UG=Hs.278626 ArgAbl-interacting protein ArgBP2 /FL=gb:NM_021069.1 gb:AB018320.1 NM_021069 sorbin and SH3 domain containing 2 SORBS2 8470 NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204289_at BG399778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG399778 /FEA=EST /DB_XREF=gi:13293226 /DB_XREF=est:602441382F1 /CLONE=IMAGE:4556900 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:NM_005589.1 gb:BC004909.1 gb:M93405.1 gb:AF148505.1 gb:AF159889.1 BG399778 aldehyde dehydrogenase 6 family, member A1 ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 204290_s_at NM_005589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005589.1 /DEF=Homo sapiens methylmalonate-semialdehyde dehydrogenase (MMSDH), mRNA. /FEA=mRNA /GEN=MMSDH /PROD=methylmalonate-semialdehyde dehydrogenase /DB_XREF=gi:11095440 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:NM_005589.1 gb:BC004909.1 gb:M93405.1 gb:AF148505.1 gb:AF159889.1 NM_005589 aldehyde dehydrogenase 6 family, member A1 ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 204291_at NM_014803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014803.1 /DEF=Homo sapiens KIAA0335 gene product (KIAA0335), mRNA. /FEA=mRNA /GEN=KIAA0335 /PROD=KIAA0335 gene product /DB_XREF=gi:7662059 /UG=Hs.29878 KIAA0335 gene product /FL=gb:AB002333.1 gb:NM_014803.1 NM_014803 zinc finger protein 518A ZNF518A 9849 NM_001278524 /// NM_001278525 /// NM_001278526 /// NM_014803 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204292_x_at NM_000455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000455.1 /DEF=Homo sapiens serinethreonine kinase 11 (Peutz-Jeghers syndrome) (STK11), mRNA. /FEA=mRNA /GEN=STK11 /PROD=serinethreonine protein kinase 11 /DB_XREF=gi:4507270 /UG=Hs.301772 serinethreonine kinase 11 (Peutz-Jeghers syndrome) /FL=gb:U63333.1 gb:AF035625.1 gb:NM_000455.1 NM_000455 serine/threonine kinase 11 STK11 6794 NM_000455 /// XM_005259617 /// XM_005259618 0001558 // regulation of cell growth // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010212 // response to ionizing radiation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0036399 // TCR signalosome assembly // inferred from electronic annotation /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043276 // anoikis // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0036398 // TCR signalosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204293_at NM_000199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000199.1 /DEF=Homo sapiens N-sulfoglucosamine sulfohydrolase (sulfamidase) (SGSH), mRNA. /FEA=mRNA /GEN=SGSH /PROD=N-sulfoglucosamine sulfohydrolase (sulfamidase) /DB_XREF=gi:4506918 /UG=Hs.31074 N-sulfoglucosamine sulfohydrolase (sulfamidase) /FL=gb:U30894.1 gb:NM_000199.1 NM_000199 N-sulfoglucosamine sulfohydrolase SGSH 6448 NM_000199 /// XM_005257582 /// XM_005257583 /// XR_429917 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006029 // proteoglycan metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016250 // N-sulfoglucosamine sulfohydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204294_at NM_000481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000481.1 /DEF=Homo sapiens aminomethyltransferase (glycine cleavage system protein T) (AMT), mRNA. /FEA=mRNA /GEN=AMT /PROD=aminomethyltransferase (glycine cleavage systemprotein T) /DB_XREF=gi:4502082 /UG=Hs.102 aminomethyltransferase (glycine cleavage system protein T) /FL=gb:D13811.1 gb:NM_000481.1 NM_000481 aminomethyltransferase AMT 275 NM_000481 /// NM_001164710 /// NM_001164711 /// NM_001164712 /// NR_028435 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204295_at NM_003172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003172.1 /DEF=Homo sapiens surfeit 1 (SURF1), mRNA. /FEA=mRNA /GEN=SURF1 /PROD=surfeit 1 /DB_XREF=gi:4507318 /UG=Hs.3196 surfeit 1 /FL=gb:NM_003172.1 NM_003172 surfeit 1 SURF1 6834 NM_001280787 /// NM_003172 /// XM_006717255 /// XM_006717256 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204296_at NM_021196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021196.1 /DEF=Homo sapiens sodium bicarbonate transporter 4 (NBC4), mRNA. /FEA=mRNA /GEN=NBC4 /PROD=sodium bicarbonate transporter 4 /DB_XREF=gi:10864004 /UG=Hs.321127 sodium bicarbonate transporter 4 /FL=gb:NM_021196.1 NM_021196 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 SLC4A5 57835 NM_021196 /// NM_033323 /// NM_133478 /// NM_133479 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005869 // dynactin complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation 204297_at NM_002647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002647.1 /DEF=Homo sapiens phosphoinositide-3-kinase, class 3 (PIK3C3), mRNA. /FEA=mRNA /GEN=PIK3C3 /PROD=phosphoinositide-3-kinase, class 3 /DB_XREF=gi:4505800 /UG=Hs.32971 phosphoinositide-3-kinase, class 3 /FL=gb:NM_002647.1 NM_002647 phosphatidylinositol 3-kinase, catalytic subunit type 3 PIK3C3 5289 NM_002647 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043201 // response to leucine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // inferred from electronic annotation 204298_s_at NM_002317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002317.1 /DEF=Homo sapiens lysyl oxidase (LOX), mRNA. /FEA=mRNA /GEN=LOX /PROD=lysyl oxidase /DB_XREF=gi:4505008 /UG=Hs.102267 lysyl oxidase /FL=gb:M94054.1 gb:AF039291.1 gb:NM_002317.1 NM_002317 lysyl oxidase LOX 4015 NM_001178102 /// NM_002317 0001568 // blood vessel development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0004720 // protein-lysine 6-oxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204299_at NM_021993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021993.1 /DEF=Homo sapiens TLS-associated serine-arginine protein 2 (TASR2), mRNA. /FEA=mRNA /GEN=TASR2 /PROD=TLS-associated serine-arginine protein 2 /DB_XREF=gi:12056475 /UG=Hs.3530 TLS-associated serine-arginine protein 2 /FL=gb:NM_021993.1 gb:BC005039.1 gb:AF067730.1 NM_021993 serine/arginine-rich splicing factor 10 SRSF10 10772 NM_001191005 /// NM_001191006 /// NM_001191007 /// NM_001191009 /// NM_006625 /// NM_054016 /// NR_034035 /// XM_006710298 /// XM_006710299 /// XM_006710300 /// XM_006710301 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 204300_at NM_004564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004564.1 /DEF=Homo sapiens PET112 (yeast homolog)-like (PET112L), mRNA. /FEA=mRNA /GEN=PET112L /PROD=PET112 (yeast homolog)-like /DB_XREF=gi:4758893 /UG=Hs.11127 PET112 (yeast homolog)-like /FL=gb:AF026851.1 gb:NM_004564.1 gb:AF151033.1 NM_004564 PET112 homolog (yeast) PET112 5188 NM_004564 /// XM_005263063 0006412 // translation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 204301_at NM_014867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014867.1 /DEF=Homo sapiens KIAA0711 gene product (KIAA0711), mRNA. /FEA=mRNA /GEN=KIAA0711 /PROD=KIAA0711 gene product /DB_XREF=gi:7662259 /UG=Hs.5333 KIAA0711 gene product /FL=gb:AB018254.1 gb:NM_014867.1 NM_014867 kelch repeat and BTB (POZ) domain containing 11 KBTBD11 9920 NM_014867 /// XM_005266043 /// XM_005266044 /// XM_005266045 /// XM_006725112 /// XM_006725113 /// XM_006725114 0005515 // protein binding // inferred from electronic annotation 204302_s_at U55962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U55962 /FEA=EST /DB_XREF=gi:1354518 /DB_XREF=est:HSU55962 /CLONE=41430 /UG=Hs.64096 KIAA0427 gene product /FL=gb:AB007887.1 gb:NM_014772.1 U55962 CBP80/20-dependent translation initiation factor CTIF 9811 NM_001142397 /// NM_014772 /// XM_005258392 /// XM_006722583 /// XM_006722584 /// XM_006722585 /// XM_006722586 /// XM_006722587 /// XM_006722588 /// XM_006722589 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204303_s_at NM_014772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014772.1 /DEF=Homo sapiens KIAA0427 gene product (KIAA0427), mRNA. /FEA=mRNA /GEN=KIAA0427 /PROD=KIAA0427 gene product /DB_XREF=gi:7662111 /UG=Hs.64096 KIAA0427 gene product /FL=gb:AB007887.1 gb:NM_014772.1 NM_014772 CBP80/20-dependent translation initiation factor CTIF 9811 NM_001142397 /// NM_014772 /// XM_005258392 /// XM_006722583 /// XM_006722584 /// XM_006722585 /// XM_006722586 /// XM_006722587 /// XM_006722588 /// XM_006722589 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204304_s_at NM_006017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006017.1 /DEF=Homo sapiens prominin (mouse)-like 1 (PROML1), mRNA. /FEA=mRNA /GEN=PROML1 /PROD=prominin (mouse)-like 1 /DB_XREF=gi:5174386 /UG=Hs.112360 prominin (mouse)-like 1 /FL=gb:AF027208.1 gb:NM_006017.1 NM_006017 prominin 1 PROM1 8842 NM_001145847 /// NM_001145848 /// NM_001145849 /// NM_001145850 /// NM_001145851 /// NM_001145852 /// NM_006017 /// XM_005248195 /// XM_005248196 /// XM_006713973 /// XM_006713974 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0060042 // retina morphogenesis in camera-type eye // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042805 // actinin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from physical interaction 204305_at NM_005932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005932.1 /DEF=Homo sapiens mitochondrial intermediate peptidase (MIPEP), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MIPEP /PROD=mitochondrial intermediate peptidase /DB_XREF=gi:5174566 /UG=Hs.68583 mitochondrial intermediate peptidase /FL=gb:U80034.1 gb:NM_005932.1 NM_005932 mitochondrial intermediate peptidase MIPEP 4285 NM_005932 0006508 // proteolysis // inferred from electronic annotation /// 0006627 // protein processing involved in protein targeting to mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204306_s_at NM_004357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004357.1 /DEF=Homo sapiens CD151 antigen (CD151), mRNA. /FEA=mRNA /GEN=CD151 /PROD=CD151 antigen /DB_XREF=gi:4757941 /UG=Hs.75564 CD151 antigen /FL=gb:BC001374.1 gb:D29963.1 gb:NM_004357.1 gb:U14650.1 NM_004357 CD151 molecule (Raph blood group) CD151 977 NM_001039490 /// NM_004357 /// NM_139029 /// NM_139030 0007155 // cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204307_at AB002295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002295.1 /DEF=Human mRNA for KIAA0297 gene, partial cds. /FEA=mRNA /GEN=KIAA0297 /DB_XREF=gi:2224534 /UG=Hs.11711 KIAA0329 gene product /FL=gb:AB002327.1 gb:NM_014844.1 AB002295 tectonin beta-propeller repeat containing 2 TECPR2 9895 NM_001172631 /// NM_014844 /// XM_005268246 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204308_s_at NM_014844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014844.1 /DEF=Homo sapiens KIAA0329 gene product (KIAA0329), mRNA. /FEA=mRNA /GEN=KIAA0329 /PROD=KIAA0329 gene product /DB_XREF=gi:7662057 /UG=Hs.11711 KIAA0329 gene product /FL=gb:AB002327.1 gb:NM_014844.1 NM_014844 tectonin beta-propeller repeat containing 2 TECPR2 9895 NM_001172631 /// NM_014844 /// XM_005268246 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204309_at NM_000781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000781.1 /DEF=Homo sapiens cytochrome P450, subfamily XIA (cholesterol side chain cleavage) (CYP11A), mRNA. /FEA=mRNA /GEN=CYP11A /PROD=cytochrome P450, subfamily XIA (cholesterol sidechain cleavage) /DB_XREF=gi:4503188 /UG=Hs.76205 cytochrome P450, subfamily XIA (cholesterol side chain cleavage) /FL=gb:M14565.1 gb:NM_000781.1 NM_000781 cytochrome P450, family 11, subfamily A, polypeptide 1 CYP11A1 1583 NM_000781 /// NM_001099773 /// XM_006720404 /// XM_006720405 0001101 // response to acid // inferred from electronic annotation /// 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // inferred from direct assay /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007617 // mating behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008203 // cholesterol metabolic process // inferred from sequence or structural similarity /// 0008207 // C21-steroid hormone metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0017085 // response to insecticide // inferred from electronic annotation /// 0018879 // biphenyl metabolic process // inferred from electronic annotation /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0018958 // phenol-containing compound metabolic process // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0033595 // response to genistein // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050756 // fractalkine metabolic process // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060014 // granulosa cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0061370 // testosterone biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008386 // cholesterol monooxygenase (side-chain-cleaving) activity // inferred from direct assay /// 0008386 // cholesterol monooxygenase (side-chain-cleaving) activity // inferred from sequence or structural similarity /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204310_s_at NM_003995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003995.2 /DEF=Homo sapiens natriuretic peptide receptor Bguanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), mRNA. /FEA=mRNA /GEN=NPR2 /PROD=natriuretic peptide receptor B precursor,isoform b /DB_XREF=gi:4580421 /UG=Hs.78518 natriuretic peptide receptor Bguanylate cyclase B (atrionatriuretic peptide receptor B) /FL=gb:NM_003995.2 NM_003995 natriuretic peptide receptor 2 NPR2 4882 NM_000907 /// NM_003995 /// XM_005251478 /// XM_005251479 /// XM_006716778 0001503 // ossification // inferred from electronic annotation /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0008217 // regulation of blood pressure // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from expression pattern 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 204311_at NM_001678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001678.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, beta 2 polypeptide (ATP1B2), mRNA. /FEA=mRNA /GEN=ATP1B2 /PROD=ATPase, Na+K+ transporting, beta 2 polypeptide /DB_XREF=gi:4502278 /UG=Hs.78854 ATPase, Na+K+ transporting, beta 2 polypeptide /FL=gb:U45945.1 gb:M81181.1 gb:NM_001678.1 NM_001678 ATPase, Na+/K+ transporting, beta 2 polypeptide ATP1B2 482 NM_001678 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005391 // sodium:potassium-exchanging ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204312_x_at AI655737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655737 /FEA=EST /DB_XREF=gi:4739716 /DB_XREF=est:tt14h05.x1 /CLONE=IMAGE:2240793 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1 AI655737 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204313_s_at AA161486 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA161486 /FEA=EST /DB_XREF=gi:1735796 /DB_XREF=est:zq42d09.s1 /CLONE=IMAGE:632369 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1 AA161486 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204314_s_at NM_004379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004379.1 /DEF=Homo sapiens cAMP responsive element binding protein 1 (CREB1), mRNA. /FEA=mRNA /GEN=CREB1 /PROD=cAMP responsive element binding protein 1 /DB_XREF=gi:4758053 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1 NM_004379 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204315_s_at AI340239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI340239 /FEA=EST /DB_XREF=gi:4077166 /DB_XREF=est:qx86a08.x1 /CLONE=IMAGE:2009366 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1 AI340239 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204316_at W19676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W19676 /FEA=EST /DB_XREF=gi:1295644 /DB_XREF=est:zb36h07.r1 /CLONE=IMAGE:305725 /UG=Hs.82280 regulator of G-protein signalling 10 /FL=gb:NM_002925.2 gb:AF045229.1 W19676 regulator of G-protein signaling 10 RGS10 6001 NM_001005339 /// NM_002925 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 204317_at BF305380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF305380 /FEA=EST /DB_XREF=gi:11252279 /DB_XREF=est:601892858F1 /CLONE=IMAGE:4138335 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1 BF305380 G-2 and S-phase expressed 1 /// tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase GTSE1 /// TRMU 51512 /// 55687 NM_001008569 /// NM_001008571 /// NM_001282782 /// NM_001282783 /// NM_001282784 /// NM_001282785 /// NM_016426 /// NM_018006 /// NR_104240 /// NR_104241 /// XM_005261627 /// XM_005261678 /// XM_005261681 0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204318_s_at NM_016426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016426.1 /DEF=Homo sapiens G-2 and S-phase expressed 1 (GTSE1), mRNA. /FEA=mRNA /GEN=GTSE1 /PROD=G-2 and S-phase expressed 1 /DB_XREF=gi:7705291 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1 NM_016426 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204319_s_at NM_002925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002925.2 /DEF=Homo sapiens regulator of G-protein signalling 10 (RGS10), mRNA. /FEA=mRNA /GEN=RGS10 /PROD=regulator of G-protein signaling 10 /DB_XREF=gi:11184225 /UG=Hs.82280 regulator of G-protein signalling 10 /FL=gb:NM_002925.2 gb:AF045229.1 NM_002925 regulator of G-protein signaling 10 RGS10 6001 NM_001005339 /// NM_002925 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 204320_at NM_001854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001854.1 /DEF=Homo sapiens collagen, type XI, alpha 1 (COL11A1), mRNA. /FEA=mRNA /GEN=COL11A1 /PROD=collagen, type XI, alpha 1 /DB_XREF=gi:4502938 /UG=Hs.82772 collagen, type XI, alpha 1 /FL=gb:J04177.1 gb:NM_001854.1 NM_001854 collagen, type XI, alpha 1 COL11A1 1301 NM_001190709 /// NM_001854 /// NM_080629 /// NM_080630 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0035989 // tendon development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // inferred from direct assay /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // non-traceable author statement 204321_at NM_002499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002499.1 /DEF=Homo sapiens neogenin (chicken) homolog 1 (NEO1), mRNA. /FEA=mRNA /GEN=NEO1 /PROD=neogenin (chicken) homolog 1 /DB_XREF=gi:4505374 /UG=Hs.90408 neogenin (chicken) homolog 1 /FL=gb:U61262.1 gb:U72391.1 gb:NM_002499.1 NM_002499 neogenin 1 NEO1 4756 NM_001172623 /// NM_001172624 /// NM_002499 /// XM_005254408 /// XM_005254410 /// XM_005254411 /// XM_005254412 /// XM_005254413 /// XM_005254414 /// XM_005254415 /// XM_005254416 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0055072 // iron ion homeostasis // inferred from genetic interaction 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 204322_at BF002254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002254 /FEA=EST /DB_XREF=gi:10702529 /DB_XREF=est:7h02a03.x1 /CLONE=IMAGE:3314764 /UG=Hs.143600 type II Golgi membrane protein /FL=gb:U55853.1 gb:NM_014498.1 BF002254 golgi integral membrane protein 4 GOLIM4 27333 NM_014498 /// XM_005247364 /// XM_005247365 /// XM_005247366 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005801 // cis-Golgi network // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 204323_x_at M61213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M61213.1 /DEF=Human neurofibromatosis type 1 (NF1) mRNA, complete cds. /FEA=mRNA /GEN=NF1 /PROD=neurofibromatosis protein type 1 /DB_XREF=gi:189162 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:M61213.1 gb:M82814.1 gb:NM_000267.1 M61213 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 204324_s_at NM_014498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014498.1 /DEF=Homo sapiens type II Golgi membrane protein (GPP130), mRNA. /FEA=mRNA /GEN=GPP130 /PROD=type II Golgi membrane protein /DB_XREF=gi:7657137 /UG=Hs.143600 type II Golgi membrane protein /FL=gb:U55853.1 gb:NM_014498.1 NM_014498 golgi integral membrane protein 4 GOLIM4 27333 NM_014498 /// XM_005247364 /// XM_005247365 /// XM_005247366 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005801 // cis-Golgi network // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 204325_s_at NM_000267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000267.1 /DEF=Homo sapiens neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) (NF1), mRNA. /FEA=mRNA /GEN=NF1 /PROD=neurofibromin /DB_XREF=gi:4557792 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:M61213.1 gb:M82814.1 gb:NM_000267.1 NM_000267 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 204326_x_at NM_002450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002450.1 /DEF=Homo sapiens metallothionein 1L (MT1L), mRNA. /FEA=mRNA /GEN=MT1L /PROD=metallothionein 1L /DB_XREF=gi:4505270 /UG=Hs.94360 metallothionein 1L /FL=gb:NM_002450.1 NM_002450 metallothionein 1X MT1X 4501 NM_005952 0010038 // response to metal ion // traceable author statement /// 0036018 // cellular response to erythropoietin // inferred from expression pattern /// 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // traceable author statement 204327_s_at N91520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N91520 /FEA=EST /DB_XREF=gi:1444847 /DB_XREF=est:za91h09.s1 /CLONE=IMAGE:299969 /UG=Hs.9443 zinc finger protein 202 /FL=gb:NM_003455.1 gb:AF027218.1 gb:AF027219.1 N91520 zinc finger protein 202 ZNF202 7753 NM_003455 /// XM_005271659 /// XM_005271660 /// XM_005271661 /// XM_005271662 /// XM_005271663 /// XM_005271664 /// XM_006718900 /// XM_006718901 /// XM_006718902 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204328_at NM_007267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007267.2 /DEF=Homo sapiens expressed in activated TLAK lymphocytes (LAK-4P), mRNA. /FEA=mRNA /GEN=LAK-4P /PROD=expressed in activated TLAK lymphocytes /DB_XREF=gi:7305226 /UG=Hs.16165 expressed in activated TLAK lymphocytes /FL=gb:AB002405.2 gb:NM_007267.2 NM_007267 transmembrane channel-like 6 TMC6 11322 NM_001127198 /// NM_007267 /// XM_005256995 /// XM_005256996 /// XM_005256997 /// XM_005256998 /// XR_243632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204329_s_at N46430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N46430 /FEA=EST /DB_XREF=gi:1187596 /DB_XREF=est:yy75g11.s1 /CLONE=IMAGE:279428 /UG=Hs.9443 zinc finger protein 202 /FL=gb:NM_003455.1 gb:AF027218.1 gb:AF027219.1 N46430 zinc finger protein 202 ZNF202 7753 NM_003455 /// XM_005271659 /// XM_005271660 /// XM_005271661 /// XM_005271662 /// XM_005271663 /// XM_005271664 /// XM_006718900 /// XM_006718901 /// XM_006718902 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204330_s_at AA587905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA587905 /FEA=EST /DB_XREF=gi:2402080 /DB_XREF=est:nm71c09.s1 /CLONE=IMAGE:1073680 /UG=Hs.9964 mitochondrial ribosomal protein S12 /FL=gb:NM_021107.1 AA587905 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204331_s_at NM_021107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021107.1 /DEF=Homo sapiens mitochondrial ribosomal protein S12 (MRPS12), mRNA. /FEA=mRNA /GEN=MRPS12 /PROD=mitochondrial ribosomal protein S12 /DB_XREF=gi:11056055 /UG=Hs.9964 mitochondrial ribosomal protein S12 /FL=gb:NM_021107.1 NM_021107 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204332_s_at M64073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M64073.1 /DEF=Human glycosylasparaginase mRNA, complete cds. /FEA=CDS /PROD=glycosylasparaginase /DB_XREF=gi:183329 /UG=Hs.207776 aspartylglucosaminidase /FL=gb:M64073.1 gb:NM_000027.1 M64073 aspartylglucosaminidase AGA 175 NM_000027 /// NM_001171988 /// NR_033655 /// XM_006714123 0006508 // proteolysis // inferred from electronic annotation /// 0006517 // protein deglycosylation // inferred from direct assay /// 0006517 // protein deglycosylation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204333_s_at NM_000027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000027.1 /DEF=Homo sapiens aspartylglucosaminidase (AGA), mRNA. /FEA=mRNA /GEN=AGA /PROD=aspartylglucosaminidase precursor /DB_XREF=gi:4557272 /UG=Hs.207776 aspartylglucosaminidase /FL=gb:M64073.1 gb:NM_000027.1 NM_000027 aspartylglucosaminidase AGA 175 NM_000027 /// NM_001171988 /// NR_033655 /// XM_006714123 0006508 // proteolysis // inferred from electronic annotation /// 0006517 // protein deglycosylation // inferred from direct assay /// 0006517 // protein deglycosylation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204334_at AA488672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA488672 /FEA=EST /DB_XREF=gi:2216103 /DB_XREF=est:ab40d10.s1 /CLONE=IMAGE:843283 /UG=Hs.21599 Kruppel-like factor 7 (ubiquitous) /FL=gb:AB015132.1 gb:NM_003709.1 AA488672 Kruppel-like factor 7 (ubiquitous) KLF7 8609 NM_001270942 /// NM_001270943 /// NM_001270944 /// NM_003709 /// NR_073108 /// XM_005246926 /// XM_006712815 /// XM_006712816 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204335_at NM_018074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018074.1 /DEF=Homo sapiens hypothetical protein FLJ10374 (FLJ10374), mRNA. /FEA=mRNA /GEN=FLJ10374 /PROD=hypothetical protein FLJ10374 /DB_XREF=gi:8922381 /UG=Hs.21811 hypothetical protein FLJ10374 /FL=gb:BC000561.1 gb:NM_018074.1 NM_018074 coiled-coil domain containing 94 CCDC94 55702 NM_018074 204336_s_at NM_005873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005873.1 /DEF=Homo sapiens regulator of G-protein signalling 19 (RGS19), mRNA. /FEA=mRNA /GEN=RGS19 /PROD=G protein signalling regulator 19 /DB_XREF=gi:5031704 /UG=Hs.22698 regulator of G-protein signalling 19 /FL=gb:NM_005873.1 NM_005873 regulator of G-protein signaling 19 RGS19 10287 NM_001039467 /// NM_005873 /// XM_005260182 /// XM_005260183 0006914 // autophagy // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 204337_at AL514445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL514445 /FEA=EST /DB_XREF=gi:12777939 /DB_XREF=est:AL514445 /CLONE=CL0BB010ZF08 (3 prime) /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1 AL514445 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204338_s_at NM_005613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005613.2 /DEF=Homo sapiens regulator of G-protein signalling 4 (RGS4), mRNA. /FEA=mRNA /GEN=RGS4 /PROD=regulator of G-protein signaling 4 /DB_XREF=gi:11184227 /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1 NM_005613 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204339_s_at BC000737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000737.1 /DEF=Homo sapiens, regulator of G-protein signalling 4, clone MGC:2124, mRNA, complete cds. /FEA=mRNA /PROD=regulator of G-protein signalling 4 /DB_XREF=gi:12653888 /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1 BC000737 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204340_at NM_003492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003492.1 /DEF=Homo sapiens chromosome X open reading frame 12 (CXORF12), mRNA. /FEA=mRNA /GEN=CXORF12 /PROD=chromosome X open reading frame 12 /DB_XREF=gi:4504738 /UG=Hs.23119 chromosome X open reading frame 12 /FL=gb:NM_003492.1 NM_003492 transmembrane protein 187 TMEM187 8269 NM_003492 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 204341_at NM_006470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006470.1 /DEF=Homo sapiens estrogen-responsive B box protein (EBBP), mRNA. /FEA=mRNA /GEN=EBBP /PROD=estrogen-responsive B box protein /DB_XREF=gi:5453643 /UG=Hs.241305 estrogen-responsive B box protein /FL=gb:AF096870.1 gb:NM_006470.1 NM_006470 tripartite motif containing 16 TRIM16 10626 NM_006470 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0060416 // response to growth hormone // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019966 // interleukin-1 binding // inferred from physical interaction /// 0032089 // NACHT domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204342_at NM_013386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013386.1 /DEF=Homo sapiens hypothetical protein (DKFZp586G0123), mRNA. /FEA=mRNA /GEN=DKFZp586G0123 /PROD=hypothetical protein /DB_XREF=gi:9558726 /UG=Hs.24713 hypothetical protein /FL=gb:AL050209.1 gb:NM_013386.1 NM_013386 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 SLC25A24 29957 NM_013386 /// NM_213651 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from mutant phenotype /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0015867 // ATP transport // inferred from mutant phenotype /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005347 // ATP transmembrane transporter activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204343_at NM_001089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001089.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3), mRNA. /FEA=mRNA /GEN=ABCA3 /PROD=ATP-binding cassette, sub-family A member 3 /DB_XREF=gi:4501848 /UG=Hs.26630 ATP-binding cassette, sub-family A (ABC1), member 3 /FL=gb:U78735.1 gb:NM_001089.1 NM_001089 ATP-binding cassette, sub-family A (ABC1), member 3 ABCA3 21 NM_001089 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from direct assay /// 0097233 // alveolar lamellar body membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // traceable author statement 204344_s_at NM_006364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006364.1 /DEF=Homo sapiens Sec23 (S. cerevisiae) homolog A (SEC23A), mRNA. /FEA=mRNA /GEN=SEC23A /PROD=Sec23 (S. cerevisiae) homolog A /DB_XREF=gi:5454041 /UG=Hs.272927 Sec23 (S. cerevisiae) homolog A /FL=gb:NM_006364.1 NM_006364 Sec23 homolog A (S. cerevisiae) SEC23A 10484 NM_006364 /// XM_005267262 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0030868 // smooth endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 204345_at NM_001856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001856.1 /DEF=Homo sapiens collagen, type XVI, alpha 1 (COL16A1), mRNA. /FEA=mRNA /GEN=COL16A1 /PROD=collagen, type XVI, alpha 1 /DB_XREF=gi:11386158 /UG=Hs.26208 collagen, type XVI, alpha 1 /FL=gb:NM_001856.1 gb:M92642.1 NM_001856 collagen, type XVI, alpha 1 COL16A1 1307 NM_001856 /// XM_005270481 0007155 // cell adhesion // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005597 // collagen type XVI trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204346_s_at NM_007182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007182.2 /DEF=Homo sapiens Ras association (RalGDSAF-6) domain family 1 (RASSF1), mRNA. /FEA=mRNA /GEN=RASSF1 /PROD=Ras association (RalGDSAF-6) domain family 1 /DB_XREF=gi:9256633 /UG=Hs.26931 Ras association (RalGDSAF-6) domain family 1 /FL=gb:AF061836.1 gb:AF132676.1 gb:AF040703.2 gb:NM_007182.2 NM_007182 Ras association (RalGDS/AF-6) domain family member 1 RASSF1 11186 NM_001206957 /// NM_007182 /// NM_170712 /// NM_170713 /// NM_170714 /// NM_170715 /// NM_170716 /// NM_170717 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 204347_at AI653169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653169 /FEA=EST /DB_XREF=gi:4737148 /DB_XREF=est:wb43g08.x1 /CLONE=IMAGE:2308478 /UG=Hs.274691 adenylate kinase 3 /FL=gb:NM_013410.1 AI653169 adenylate kinase 4 /// adenylate kinase 4, mitochondrial-like AK4 /// LOC100507855 205 /// 100507855 NM_001005353 /// NM_013410 /// NM_203464 /// XM_003119530 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018885 // carbon tetrachloride metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043643 // tetracycline metabolic process // inferred from electronic annotation /// 0046033 // AMP metabolic process // inferred from direct assay /// 0046034 // ATP metabolic process // inferred from direct assay /// 0046039 // GTP metabolic process // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0046899 // nucleoside triphosphate adenylate kinase activity // inferred from direct assay 204348_s_at NM_013410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013410.1 /DEF=Homo sapiens adenylate kinase 3 (AK3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=AK3 /PROD=adenylate kinase 3 /DB_XREF=gi:8051578 /UG=Hs.274691 adenylate kinase 3 /FL=gb:NM_013410.1 NM_013410 adenylate kinase 4 /// adenylate kinase 4, mitochondrial-like AK4 /// LOC100507855 205 /// 100507855 NM_001005353 /// NM_013410 /// NM_203464 /// XM_003119530 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018885 // carbon tetrachloride metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043643 // tetracycline metabolic process // inferred from electronic annotation /// 0046033 // AMP metabolic process // inferred from direct assay /// 0046034 // ATP metabolic process // inferred from direct assay /// 0046039 // GTP metabolic process // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0046899 // nucleoside triphosphate adenylate kinase activity // inferred from direct assay 204349_at BC005250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005250.1 /DEF=Homo sapiens, cofactor required for Sp1 transcriptional activation, subunit 9 (33kD), clone MGC:12284, mRNA, complete cds. /FEA=mRNA /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 9 (33kD) /DB_XREF=gi:13528908 /UG=Hs.279902 cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) /FL=gb:BC005250.1 gb:AF031383.1 gb:AF104251.1 gb:NM_004270.1 BC005250 mediator complex subunit 7 MED7 9443 NM_001100816 /// NM_004270 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204350_s_at NM_004270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004270.1 /DEF=Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) (CRSP9), mRNA. /FEA=mRNA /GEN=CRSP9 /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 9 (33kD) /DB_XREF=gi:4758063 /UG=Hs.279902 cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) /FL=gb:BC005250.1 gb:AF031383.1 gb:AF104251.1 gb:NM_004270.1 NM_004270 mediator complex subunit 7 MED7 9443 NM_001100816 /// NM_004270 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204351_at NM_005980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005980.1 /DEF=Homo sapiens S100 calcium-binding protein P (S100P), mRNA. /FEA=mRNA /GEN=S100P /PROD=S100 calcium-binding protein P /DB_XREF=gi:5174662 /UG=Hs.2962 S100 calcium-binding protein P /FL=gb:NM_005980.1 NM_005980 S100 calcium binding protein P S100P 6286 NM_005980 0010033 // response to organic substance // inferred from expression pattern /// 0043542 // endothelial cell migration // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0050786 // RAGE receptor binding // inferred from electronic annotation 204352_at NM_004619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004619.1 /DEF=Homo sapiens TNF receptor-associated factor 5 (TRAF5), mRNA. /FEA=mRNA /GEN=TRAF5 /PROD=TNF receptor-associated factor 5 /DB_XREF=gi:11321602 /UG=Hs.29736 TNF receptor-associated factor 5 /FL=gb:NM_004619.1 gb:AB000509.1 NM_004619 TNF receptor-associated factor 5 TRAF5 7188 NM_001033910 /// NM_004619 /// NM_145759 /// XM_005273249 /// XM_006711524 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204353_s_at BC002923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002923.1 /DEF=Homo sapiens, clone MGC:10280, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10280) /DB_XREF=gi:12804138 /UG=Hs.31968 DKFZP586D211 protein /FL=gb:BC002923.1 gb:NM_015450.1 BC002923 protection of telomeres 1 POT1 25913 NM_001042594 /// NM_015450 /// NR_003102 /// NR_003103 /// NR_003104 /// XM_006715917 0000723 // telomere maintenance // traceable author statement /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0016233 // telomere capping // inferred from genetic interaction /// 0016233 // telomere capping // inferred from mutant phenotype /// 0032203 // telomere formation via telomerase // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0051974 // negative regulation of telomerase activity // inferred from direct assay /// 0060383 // positive regulation of DNA strand elongation // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010521 // telomerase inhibitor activity // inferred from direct assay /// 0017151 // DEAD/H-box RNA helicase binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay /// 0043047 // single-stranded telomeric DNA binding // inferred from mutant phenotype 204354_at NM_015450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015450.1 /DEF=Homo sapiens DKFZP586D211 protein (DKFZP586D211), mRNA. /FEA=mRNA /GEN=DKFZP586D211 /PROD=DKFZP586D211 protein /DB_XREF=gi:13123773 /UG=Hs.31968 DKFZP586D211 protein /FL=gb:BC002923.1 gb:NM_015450.1 NM_015450 protection of telomeres 1 POT1 25913 NM_001042594 /// NM_015450 /// NR_003102 /// NR_003103 /// NR_003104 /// XM_006715917 0000723 // telomere maintenance // traceable author statement /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0016233 // telomere capping // inferred from genetic interaction /// 0016233 // telomere capping // inferred from mutant phenotype /// 0032203 // telomere formation via telomerase // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0051974 // negative regulation of telomerase activity // inferred from direct assay /// 0060383 // positive regulation of DNA strand elongation // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010521 // telomerase inhibitor activity // inferred from direct assay /// 0017151 // DEAD/H-box RNA helicase binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay /// 0043047 // single-stranded telomeric DNA binding // inferred from mutant phenotype 204355_at NM_014966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014966.1 /DEF=Homo sapiens KIAA0890 protein (KIAA0890), mRNA. /FEA=mRNA /GEN=KIAA0890 /PROD=KIAA0890 protein /DB_XREF=gi:7662361 /UG=Hs.323462 KIAA0890 protein /FL=gb:AB020697.1 gb:NM_014966.1 NM_014966 DEAH (Asp-Glu-Ala-His) box helicase 30 DHX30 22907 NM_014966 /// NM_138614 /// NM_138615 /// NR_075079 /// XM_006713032 /// XM_006713033 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204356_at D26309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D26309.1 /DEF=Human mRNA for LIMK (LIM kinase), complete cds. /FEA=mRNA /GEN=limk /PROD=LIMK /DB_XREF=gi:565279 /UG=Hs.36566 LIM domain kinase 1 /FL=gb:D26309.1 gb:NM_002314.2 D26309 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204357_s_at NM_002314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002314.2 /DEF=Homo sapiens LIM domain kinase 1 (LIMK1), transcript variant 1, mRNA. /FEA=mRNA /GEN=LIMK1 /PROD=LIM domain kinase 1 isoform 1 /DB_XREF=gi:8051616 /UG=Hs.36566 LIM domain kinase 1 /FL=gb:D26309.1 gb:NM_002314.2 NM_002314 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204358_s_at AF169676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF169676.1 /DEF=Homo sapiens leucine-rich repeat transmembrane protein FLRT2 (FLRT2) mRNA, complete cds. /FEA=mRNA /GEN=FLRT2 /PROD=leucine-rich repeat transmembrane protein FLRT2 /DB_XREF=gi:6808604 /UG=Hs.48998 fibronectin leucine rich transmembrane protein 2 /FL=gb:AB007865.1 gb:AF169676.1 gb:NM_013231.1 AF169676 fibronectin leucine rich transmembrane protein 2 /// uncharacterized LOC100506718 FLRT2 /// LOC100506718 23768 /// 100506718 NM_013231 /// XM_005267489 /// XM_005267490 /// XM_006720095 /// XR_111450 /// XR_172052 /// XR_248023 /// XR_248024 /// XR_248025 /// XR_424524 /// XR_424525 /// XR_424526 /// XR_424527 /// XR_429303 /// XR_429304 /// XR_429305 /// XR_429306 /// XR_429307 /// XR_429308 /// XR_429309 /// XR_433009 /// XR_433010 /// XR_433011 /// XR_433012 /// XR_433013 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 204359_at NM_013231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013231.1 /DEF=Homo sapiens fibronectin leucine rich transmembrane protein 2 (FLRT2), mRNA. /FEA=mRNA /GEN=FLRT2 /PROD=fibronectin leucine rich transmembrane protein2 /DB_XREF=gi:7019380 /UG=Hs.48998 fibronectin leucine rich transmembrane protein 2 /FL=gb:AB007865.1 gb:AF169676.1 gb:NM_013231.1 NM_013231 fibronectin leucine rich transmembrane protein 2 /// uncharacterized LOC100506718 FLRT2 /// LOC100506718 23768 /// 100506718 NM_013231 /// XM_005267489 /// XM_005267490 /// XM_006720095 /// XR_111450 /// XR_172052 /// XR_248023 /// XR_248024 /// XR_248025 /// XR_424524 /// XR_424525 /// XR_424526 /// XR_424527 /// XR_429303 /// XR_429304 /// XR_429305 /// XR_429306 /// XR_429307 /// XR_429308 /// XR_429309 /// XR_433009 /// XR_433010 /// XR_433011 /// XR_433012 /// XR_433013 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 204360_s_at NM_000263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000263.1 /DEF=Homo sapiens N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) (NAGLU), mRNA. /FEA=mRNA /GEN=NAGLU /PROD=N-acetylglucosaminidase, alpha- (Sanfilippodisease IIIB) /DB_XREF=gi:4505326 /UG=Hs.50727 N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) /FL=gb:U43573.1 gb:U40846.1 gb:L78464.1 gb:NM_000263.1 NM_000263 N-acetylglucosaminidase, alpha NAGLU 4669 NM_000263 /// XM_006721920 /// XM_006721921 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004561 // alpha-N-acetylglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 204361_s_at AB014486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014486.1 /DEF=Homo sapiens mRNA for RA70, complete cds. /FEA=mRNA /GEN=RA70 /PROD=RA70 /DB_XREF=gi:4062959 /UG=Hs.52644 SKAP55 homologue /FL=gb:BC002893.1 gb:AF072166.1 gb:AB014486.1 gb:AF051323.1 gb:NM_003930.1 AB014486 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 204362_at NM_003930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003930.1 /DEF=Homo sapiens SKAP55 homologue (SKAP-HOM), mRNA. /FEA=mRNA /GEN=SKAP-HOM /PROD=SKAP55 homologue /DB_XREF=gi:4506962 /UG=Hs.52644 SKAP55 homologue /FL=gb:BC002893.1 gb:AF072166.1 gb:AB014486.1 gb:AF051323.1 gb:NM_003930.1 NM_003930 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 204363_at NM_001993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001993.2 /DEF=Homo sapiens coagulation factor III (thromboplastin, tissue factor) (F3), mRNA. /FEA=mRNA /GEN=F3 /PROD=coagulation factor III precursor /DB_XREF=gi:10518499 /UG=Hs.62192 coagulation factor III (thromboplastin, tissue factor) /FL=gb:NM_001993.2 gb:J02931.1 gb:M16553.1 gb:M27436.1 NM_001993 coagulation factor III (thromboplastin, tissue factor) F3 2152 NM_001178096 /// NM_001993 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002541 // activation of plasma proteins involved in acute inflammatory response // inferred from direct assay /// 0002543 // activation of blood coagulation via clotting cascade // inferred by curator /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010641 // positive regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0030335 // positive regulation of cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred by curator /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031233 // intrinsic component of external side of plasma membrane // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 204364_s_at BE535746 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE535746 /FEA=EST /DB_XREF=gi:9764391 /DB_XREF=est:601060419F1 /CLONE=IMAGE:3446788 /UG=Hs.7358 hypothetical protein FLJ13110 /FL=gb:NM_022912.1 BE535746 receptor accessory protein 1 REEP1 65055 NM_001164730 /// NM_001164731 /// NM_001164732 /// NM_022912 /// XM_005264502 /// XM_005264503 /// XM_005264504 /// XM_005264505 /// XM_006712078 0008219 // cell death // inferred from electronic annotation /// 0051205 // protein insertion into membrane // inferred from direct assay /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0031849 // olfactory receptor binding // inferred from mutant phenotype 204365_s_at NM_022912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022912.1 /DEF=Homo sapiens hypothetical protein FLJ13110 (FLJ13110), mRNA. /FEA=mRNA /GEN=FLJ13110 /PROD=hypothetical protein FLJ13110 /DB_XREF=gi:12597656 /UG=Hs.7358 hypothetical protein FLJ13110 /FL=gb:NM_022912.1 NM_022912 receptor accessory protein 1 REEP1 65055 NM_001164730 /// NM_001164731 /// NM_001164732 /// NM_022912 /// XM_005264502 /// XM_005264503 /// XM_005264504 /// XM_005264505 /// XM_006712078 0008219 // cell death // inferred from electronic annotation /// 0051205 // protein insertion into membrane // inferred from direct assay /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0031849 // olfactory receptor binding // inferred from mutant phenotype 204366_s_at NM_001521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001521.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) (GTF3C2), mRNA. /FEA=mRNA /GEN=GTF3C2 /PROD=general transcription factor IIIC, polypeptide 2(beta subunit, 110kD) /DB_XREF=gi:4504204 /UG=Hs.75782 general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) /FL=gb:D13636.1 gb:NM_001521.1 NM_001521 general transcription factor IIIC, polypeptide 2, beta 110kDa GTF3C2 2976 NM_001035521 /// NM_001521 /// XM_005264272 /// XM_005264273 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 204367_at D28588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28588.1 /DEF=Human mRNA for KIAA0048 gene, complete cds. /FEA=mRNA /GEN=KIAA0048 /DB_XREF=gi:460712 /UG=Hs.77031 Sp2 transcription factor /FL=gb:M97190.1 gb:NM_003110.1 gb:D28588.1 D28588 Sp2 transcription factor SP2 6668 NM_003110 /// XM_006722023 /// XM_006722024 /// XM_006722025 /// XM_006722026 /// XM_006722027 /// XM_006722028 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204368_at NM_005630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005630.1 /DEF=Homo sapiens solute carrier family 21 (prostaglandin transporter), member 2 (SLC21A2), mRNA. /FEA=mRNA /GEN=SLC21A2 /PROD=solute carrier family 21 (prostaglandintransporter), member 2 /DB_XREF=gi:5032094 /UG=Hs.83974 solute carrier family 21 (prostaglandin transporter), member 2 /FL=gb:U70867.1 gb:NM_005630.1 NM_005630 solute carrier organic anion transporter family, member 2A1 SLCO2A1 6578 NM_005630 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // traceable author statement /// 0015732 // prostaglandin transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015132 // prostaglandin transmembrane transporter activity // inferred from electronic annotation 204369_at NM_006218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006218.1 /DEF=Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), mRNA. /FEA=mRNA /GEN=PIK3CA /PROD=phosphoinositide-3-kinase, catalytic, alphapolypeptide /DB_XREF=gi:5453891 /UG=Hs.85701 phosphoinositide-3-kinase, catalytic, alpha polypeptide /FL=gb:U79143.1 gb:NM_006218.1 NM_006218 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha PIK3CA 5290 NM_006218 /// XM_006713658 0001525 // angiogenesis // inferred from electronic annotation /// 0001944 // vasculature development // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from direct assay /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0044029 // hypomethylation of CpG island // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0060048 // cardiac muscle contraction // traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation /// 2000653 // regulation of genetic imprinting // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from sequence or structural similarity /// 0005943 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // traceable author statement 204370_at NM_006831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006831.1 /DEF=Homo sapiens ATPGTP-binding protein (HEAB), mRNA. /FEA=mRNA /GEN=HEAB /PROD=ATPGTP-binding protein /DB_XREF=gi:5803028 /UG=Hs.87465 ATPGTP-binding protein /FL=gb:BC000446.1 gb:U73524.1 gb:NM_006831.1 NM_006831 cleavage and polyadenylation factor I subunit 1 CLP1 10978 NM_001142597 /// NM_006831 /// XM_006718425 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from direct assay /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from mutant phenotype /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0035087 // siRNA loading onto RISC involved in RNA interference // inferred from direct assay 0000214 // tRNA-intron endonuclease complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046404 // ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity // inferred from electronic annotation /// 0051733 // polydeoxyribonucleotide kinase activity // inferred from direct assay /// 0051736 // ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity // inferred from direct assay /// 0051736 // ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity // inferred from mutant phenotype 204371_s_at AI933301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI933301 /FEA=EST /DB_XREF=gi:5672038 /DB_XREF=est:wp65f12.x1 /CLONE=IMAGE:2466671 /UG=Hs.91142 KH-type splicing regulatory protein (FUSE binding protein 2) /FL=gb:U94832.1 gb:NM_003685.1 AI933301 KH-type splicing regulatory protein KHSRP 8570 NM_003685 /// XM_005259668 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204372_s_at NM_003685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003685.1 /DEF=Homo sapiens KH-type splicing regulatory protein (FUSE binding protein 2) (KHSRP), mRNA. /FEA=mRNA /GEN=KHSRP /PROD=KH-type splicing regulatory protein (FUSEbinding protein 2) /DB_XREF=gi:4504864 /UG=Hs.91142 KH-type splicing regulatory protein (FUSE binding protein 2) /FL=gb:U94832.1 gb:NM_003685.1 NM_003685 KH-type splicing regulatory protein KHSRP 8570 NM_003685 /// XM_005259668 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204373_s_at NM_014810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014810.1 /DEF=Homo sapiens KIAA0480 gene product (KIAA0480), mRNA. /FEA=mRNA /GEN=KIAA0480 /PROD=KIAA0480 gene product /DB_XREF=gi:7662155 /UG=Hs.92200 KIAA0480 gene product /FL=gb:AB007949.1 gb:NM_014810.1 NM_014810 centrosomal protein 350kDa CEP350 9857 NM_014810 /// XM_005245638 /// XM_006711666 /// XM_006711667 /// XM_006711668 /// XM_006711669 /// XM_006711670 /// XM_006711671 0034453 // microtubule anchoring // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 204374_s_at BG474736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG474736 /FEA=EST /DB_XREF=gi:13407000 /DB_XREF=est:602517557F1 /CLONE=IMAGE:4649007 /UG=Hs.92357 galactokinase 1 /FL=gb:U26401.1 gb:BC001166.1 gb:NM_000154.1 BG474736 galactokinase 1 GALK1 2584 NM_000154 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019388 // galactose catabolic process // traceable author statement /// 0019402 // galactitol metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004335 // galactokinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005534 // galactose binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204375_at NM_014718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014718.1 /DEF=Homo sapiens KIAA0726 gene product (KIAA0726), mRNA. /FEA=mRNA /GEN=KIAA0726 /PROD=KIAA0726 gene product /DB_XREF=gi:7662267 /UG=Hs.107809 KIAA0726 gene product /FL=gb:AB018269.1 gb:NM_014718.1 NM_014718 calsyntenin 3 CLSTN3 9746 NM_014718 /// XM_006719163 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 204376_at NM_014703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014703.1 /DEF=Homo sapiens KIAA0800 gene product (KIAA0800), mRNA. /FEA=mRNA /GEN=KIAA0800 /PROD=KIAA0800 gene product /DB_XREF=gi:7662315 /UG=Hs.118738 KIAA0800 gene product /FL=gb:AB018343.1 gb:NM_014703.1 NM_014703 Vpr (HIV-1) binding protein VPRBP 9730 NM_001171904 /// NM_014703 /// XM_005276751 /// XM_005276752 /// XM_005276753 /// XM_005276754 /// XM_005276755 /// XM_006713426 /// XM_006713427 /// XM_006713428 /// XR_254197 /// XR_254198 /// XR_427298 /// XR_427299 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0035212 // cell competition in a multicellular organism // inferred from mutant phenotype /// 1990245 // histone H2A-T120 phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 1990244 // histone kinase activity (H2A-T120 specific) // inferred from direct assay 204377_s_at NM_014703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014703.1 /DEF=Homo sapiens KIAA0800 gene product (KIAA0800), mRNA. /FEA=mRNA /GEN=KIAA0800 /PROD=KIAA0800 gene product /DB_XREF=gi:7662315 /UG=Hs.118738 KIAA0800 gene product /FL=gb:AB018343.1 gb:NM_014703.1 NM_014703 Vpr (HIV-1) binding protein VPRBP 9730 NM_001171904 /// NM_014703 /// XM_005276751 /// XM_005276752 /// XM_005276753 /// XM_005276754 /// XM_005276755 /// XM_006713426 /// XM_006713427 /// XM_006713428 /// XR_254197 /// XR_254198 /// XR_427298 /// XR_427299 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0035212 // cell competition in a multicellular organism // inferred from mutant phenotype /// 1990245 // histone H2A-T120 phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 1990244 // histone kinase activity (H2A-T120 specific) // inferred from direct assay 204378_at NM_003657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003657.1 /DEF=Homo sapiens breast carcinoma amplified sequence 1 (BCAS1), mRNA. /FEA=mRNA /GEN=BCAS1 /PROD=breast carcinoma amplified sequence 1 /DB_XREF=gi:4502372 /UG=Hs.129057 breast carcinoma amplified sequence 1 /FL=gb:AF041260.1 gb:NM_003657.1 NM_003657 breast carcinoma amplified sequence 1 BCAS1 8537 NM_003657 /// XM_005260587 /// XM_005260589 /// XM_005260590 /// XM_005260591 /// XM_005260592 /// XM_005260593 /// XM_005260594 /// XM_005260595 /// XM_005260596 0005737 // cytoplasm // inferred from electronic annotation 204379_s_at NM_000142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000142.2 /DEF=Homo sapiens fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) (FGFR3), transcript variant 1, mRNA. /FEA=mRNA /GEN=FGFR3 /PROD=fibroblast growth factor receptor 3, isoform 1precursor /DB_XREF=gi:13112046 /UG=Hs.1420 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) /FL=gb:NM_000142.2 gb:M58051.1 NM_000142 fibroblast growth factor receptor 3 FGFR3 2261 NM_000142 /// NM_001163213 /// NM_022965 /// XM_006713868 /// XM_006713869 /// XM_006713870 /// XM_006713871 /// XM_006713872 /// XM_006713873 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // traceable author statement /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003416 // endochondral bone growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048640 // negative regulation of developmental growth // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from electronic annotation /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070977 // bone maturation // inferred from sequence or structural similarity /// 0072148 // epithelial cell fate commitment // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1902178 // fibroblast growth factor receptor apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 204380_s_at M58051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M58051.1 /DEF=Human fibroblast growth factor receptor (FGFR3) mRNA, complete cds. /FEA=mRNA /GEN=FGFR3 /PROD=fibroblast growth factor receptor /DB_XREF=gi:182568 /UG=Hs.1420 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) /FL=gb:NM_000142.2 gb:M58051.1 M58051 fibroblast growth factor receptor 3 FGFR3 2261 NM_000142 /// NM_001163213 /// NM_022965 /// XM_006713868 /// XM_006713869 /// XM_006713870 /// XM_006713871 /// XM_006713872 /// XM_006713873 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // traceable author statement /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003416 // endochondral bone growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048640 // negative regulation of developmental growth // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from electronic annotation /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070977 // bone maturation // inferred from sequence or structural similarity /// 0072148 // epithelial cell fate commitment // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1902178 // fibroblast growth factor receptor apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 204381_at NM_002333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002333.1 /DEF=Homo sapiens low density lipoprotein receptor-related protein 3 (LRP3), mRNA. /FEA=mRNA /GEN=LRP3 /PROD=low density lipoprotein receptor-related protein3 /DB_XREF=gi:4505014 /UG=Hs.143641 low density lipoprotein receptor-related protein 3 /FL=gb:AB009462.1 gb:NM_002333.1 NM_002333 low density lipoprotein receptor-related protein 3 LRP3 4037 NM_002333 /// XM_005258945 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204382_at NM_015654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015654.1 /DEF=Homo sapiens DKFZP564C103 protein (DKFZP564C103), mRNA. /FEA=mRNA /GEN=DKFZP564C103 /PROD=DKFZP564C103 protein /DB_XREF=gi:7661603 /UG=Hs.144058 DKFZP564C103 protein /FL=gb:BC004195.1 gb:BC004225.1 gb:NM_015654.1 NM_015654 N-acetyltransferase 9 (GCN5-related, putative) NAT9 26151 NM_015654 /// XM_005257207 /// XM_005257212 /// XM_006721812 /// XM_006721813 /// XM_006721814 /// XM_006721815 /// XM_006721816 /// XR_243644 0008152 // metabolic process // inferred from electronic annotation 0043234 // protein complex // inferred from direct assay 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 204383_at NM_022719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022719.1 /DEF=Homo sapiens DiGeorge syndrome critical region gene DGSI (DGSI), mRNA. /FEA=mRNA /GEN=DGSI /PROD=DiGeorge syndrome critical region gene DGSIprotein /DB_XREF=gi:13027629 /UG=Hs.154879 DiGeorge syndrome critical region gene DGSI /FL=gb:NM_022719.1 NM_022719 DiGeorge syndrome critical region gene 14 /// testis-specific serine kinase 2 DGCR14 /// TSSK2 8220 /// 23617 NM_022719 /// NM_053006 /// XM_005261282 /// XM_006724329 /// XM_006724330 /// XM_006724331 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204384_at NM_004486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004486.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 2 (GOLGA2), mRNA. /FEA=mRNA /GEN=GOLGA2 /PROD=golgi autoantigen, golgin subfamily a, 2 /DB_XREF=gi:4758451 /UG=Hs.169055 golgi autoantigen, golgin subfamily a, 2 /FL=gb:L06147.1 gb:NM_004486.1 gb:AF248953.1 NM_004486 golgin A2 GOLGA2 2801 NM_004486 /// XM_005251930 /// XM_005251931 /// XM_005251932 0000278 // mitotic cell cycle // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 204385_at NM_003937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003937.1 /DEF=Homo sapiens kynureninase (L-kynurenine hydrolase) (KYNU), mRNA. /FEA=mRNA /GEN=KYNU /PROD=kynureninase (L-kynurenine hydrolase) /DB_XREF=gi:4504936 /UG=Hs.169139 kynureninase (L-kynurenine hydrolase) /FL=gb:U57721.1 gb:NM_003937.1 NM_003937 kynureninase KYNU 8942 NM_001032998 /// NM_001199241 /// NM_003937 0006569 // tryptophan catabolic process // inferred from mutant phenotype /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034516 // response to vitamin B6 // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030429 // kynureninase activity // inferred from direct assay /// 0030429 // kynureninase activity // inferred from mutant phenotype /// 0030429 // kynureninase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 204386_s_at BF303597 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF303597 /FEA=EST /DB_XREF=gi:11250218 /DB_XREF=est:601886230F2 /CLONE=IMAGE:4120446 /UG=Hs.182695 hypothetical protein MGC3243 /FL=gb:BC000002.1 gb:NM_024026.1 BF303597 mitochondrial ribosomal protein L57 MRPL57 78988 NM_024026 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 204387_x_at NM_024026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024026.1 /DEF=Homo sapiens hypothetical protein MGC3243 (MGC3243), mRNA. /FEA=mRNA /GEN=MGC3243 /PROD=hypothetical protein MGC3243 /DB_XREF=gi:13128969 /UG=Hs.182695 hypothetical protein MGC3243 /FL=gb:BC000002.1 gb:NM_024026.1 NM_024026 mitochondrial ribosomal protein L57 MRPL57 78988 NM_024026 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 204388_s_at NM_000240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000240.1 /DEF=Homo sapiens monoamine oxidase A (MAOA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOA /PROD=monoamine oxidase A /DB_XREF=gi:4557734 /UG=Hs.183109 monoamine oxidase A /FL=gb:M68840.1 gb:M69226.1 gb:NM_000240.1 NM_000240 monoamine oxidase A MAOA 4128 NM_000240 /// NM_001270458 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008131 // primary amine oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204389_at NM_000240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000240.1 /DEF=Homo sapiens monoamine oxidase A (MAOA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOA /PROD=monoamine oxidase A /DB_XREF=gi:4557734 /UG=Hs.183109 monoamine oxidase A /FL=gb:M68840.1 gb:M69226.1 gb:NM_000240.1 NM_000240 monoamine oxidase A MAOA 4128 NM_000240 /// NM_001270458 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008131 // primary amine oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204390_at AF009353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009353.1 /DEF=Homo sapiens transcription intermediary factor 1 (TIF1) mRNA, complete cds. /FEA=CDS /GEN=TIF1 /PROD=transcription intermediary factor 1 /DB_XREF=gi:2267584 /UG=Hs.183858 transcriptional intermediary factor 1 /FL=gb:AF009353.1 gb:AF119042.1 gb:NM_003852.1 gb:NM_015905.1 AF009353 204391_x_at NM_015905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015905.1 /DEF=Homo sapiens transcriptional intermediary factor 1 (TIF1), mRNA. /FEA=mRNA /GEN=TIF1 /PROD=transcriptional intermediary factor 1 alpha /DB_XREF=gi:7706233 /UG=Hs.183858 transcriptional intermediary factor 1 /FL=gb:AF009353.1 gb:AF119042.1 gb:NM_003852.1 gb:NM_015905.1 NM_015905 tripartite motif containing 24 TRIM24 8805 NM_003852 /// NM_015905 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 1901796 // regulation of signal transduction by p53 class mediator // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0034056 // estrogen response element binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 204392_at NM_003656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003656.2 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase I (CAMK1), mRNA. /FEA=mRNA /GEN=CAMK1 /PROD=calciumcalmodulin-dependent protein kinase I /DB_XREF=gi:4580415 /UG=Hs.184402 calciumcalmodulin-dependent protein kinase I /FL=gb:NM_003656.2 gb:L41816.1 NM_003656 calcium/calmodulin-dependent protein kinase I CAMK1 8536 NM_003656 /// XM_005265516 /// XM_005265517 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from direct assay /// 0045007 // depurination // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051835 // positive regulation of synapse structural plasticity // inferred from mutant phenotype /// 0060999 // positive regulation of dendritic spine development // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008534 // oxidized purine nucleobase lesion DNA N-glycosylase activity // inferred from electronic annotation /// 0008534 // oxidized purine nucleobase lesion DNA N-glycosylase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation /// 0034039 // 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity // inferred from electronic annotation 204393_s_at NM_001099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001099.2 /DEF=Homo sapiens acid phosphatase, prostate (ACPP), mRNA. /FEA=mRNA /GEN=ACPP /PROD=prostatic acid phosphatase precursor /DB_XREF=gi:6382063 /UG=Hs.1852 acid phosphatase, prostate /FL=gb:M24902.1 gb:M34840.1 gb:NM_001099.2 NM_001099 acid phosphatase, prostate ACPP 55 NM_001099 /// NM_001134194 /// NM_001292037 0006144 // purine nucleobase metabolic process // inferred from electronic annotation /// 0006772 // thiamine metabolic process // inferred from sequence or structural similarity /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0046085 // adenosine metabolic process // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from mutant phenotype /// 0060168 // positive regulation of adenosine receptor signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008253 // 5'-nucleotidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from mutant phenotype /// 0033265 // choline binding // inferred from electronic annotation /// 0042131 // thiamine phosphate phosphatase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052642 // lysophosphatidic acid phosphatase activity // inferred from direct assay 204394_at NM_003627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003627.1 /DEF=Homo sapiens prostate cancer overexpressed gene 1 (POV1), mRNA. /FEA=mRNA /GEN=POV1 /PROD=prostate cancer overexpressed gene 1 /DB_XREF=gi:4505970 /UG=Hs.18910 prostate cancer overexpressed gene 1 /FL=gb:BC001639.1 gb:AF045584.1 gb:NM_003627.1 NM_003627 solute carrier family 43 (amino acid system L transporter), member 1 SLC43A1 8501 NM_001198810 /// NM_003627 /// XM_005274357 /// XM_005274358 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015804 // neutral amino acid transport // inferred from direct assay /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015175 // neutral amino acid transmembrane transporter activity // inferred from direct assay /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation 204395_s_at AI338653 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI338653 /FEA=EST /DB_XREF=gi:4075580 /DB_XREF=est:qt52e03.x1 /CLONE=IMAGE:1951612 /UG=Hs.211569 G protein-coupled receptor kinase 5 /FL=gb:L15388.1 gb:NM_005308.1 AI338653 G protein-coupled receptor kinase 5 GRK5 2869 NM_005308 /// XM_005269707 /// XM_005269708 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204396_s_at NM_005308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005308.1 /DEF=Homo sapiens G protein-coupled receptor kinase 5 (GPRK5), mRNA. /FEA=mRNA /GEN=GPRK5 /PROD=G protein-coupled receptor kinase 5 /DB_XREF=gi:4885348 /UG=Hs.211569 G protein-coupled receptor kinase 5 /FL=gb:L15388.1 gb:NM_005308.1 NM_005308 G protein-coupled receptor kinase 5 GRK5 2869 NM_005308 /// XM_005269707 /// XM_005269708 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204397_at AF103939 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103939.1 /DEF=Homo sapiens echinoderm microtubule-associated protein-like EMAP2 mRNA, complete cds. /FEA=mRNA /PROD=echinoderm microtubule-associated protein-likeEMAP2 /DB_XREF=gi:4406217 /UG=Hs.24178 microtubule-associated protein like echinoderm EMAP /FL=gb:AF103939.1 gb:NM_012155.1 AF103939 echinoderm microtubule associated protein like 2 EML2 24139 NM_001193268 /// NM_001193269 /// NM_012155 /// NR_034098 /// XM_006723125 /// XM_006723126 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0010968 // regulation of microtubule nucleation // inferred from direct assay /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0072686 // mitotic spindle // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay 204398_s_at NM_012155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012155.1 /DEF=Homo sapiens microtubule-associated protein like echinoderm EMAP (EMAP-2), mRNA. /FEA=mRNA /GEN=EMAP-2 /PROD=microtubule-associated protein like echinodermEMAP /DB_XREF=gi:6912355 /UG=Hs.24178 microtubule-associated protein like echinoderm EMAP /FL=gb:AF103939.1 gb:NM_012155.1 NM_012155 echinoderm microtubule associated protein like 2 EML2 24139 NM_001193268 /// NM_001193269 /// NM_012155 /// NR_034098 /// XM_006723125 /// XM_006723126 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0010968 // regulation of microtubule nucleation // inferred from direct assay /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay 204399_s_at AI582285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI582285 /FEA=EST /DB_XREF=gi:4568182 /DB_XREF=est:tq65h11.x1 /CLONE=IMAGE:2213733 /UG=Hs.24178 microtubule-associated protein like echinoderm EMAP /FL=gb:AF103939.1 gb:NM_012155.1 AI582285 echinoderm microtubule associated protein like 2 EML2 24139 NM_001193268 /// NM_001193269 /// NM_012155 /// NR_034098 /// XM_006723125 /// XM_006723126 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0010968 // regulation of microtubule nucleation // inferred from direct assay /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay 204400_at NM_005864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005864.1 /DEF=Homo sapiens signal transduction protein (SH3 containing) (EFS2), mRNA. /FEA=mRNA /GEN=EFS2 /PROD=signal transduction protein (SH3 containing) /DB_XREF=gi:5031680 /UG=Hs.24587 signal transduction protein (SH3 containing) /FL=gb:AB001466.1 gb:NM_005864.1 NM_005864 embryonal Fyn-associated substrate EFS 10278 NM_001277174 /// NM_005864 /// NM_032459 /// XM_005267256 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 204401_at NM_002250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002250.1 /DEF=Homo sapiens potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 4 (KCNN4), mRNA. /FEA=mRNA /GEN=KCNN4 /PROD=potassium intermediatesmall conductancecalcium-activated channel, subfamily N, member 4 /DB_XREF=gi:4504858 /UG=Hs.10082 potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 4 /FL=gb:AF000972.1 gb:AF033021.1 gb:AF022150.1 gb:AF022797.1 gb:NM_002250.1 NM_002250 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 KCNN4 3783 NM_002250 /// XM_005258882 /// XM_005258883 /// XM_005258886 0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006816 // calcium ion transport // inferred from direct assay /// 0006820 // anion transport // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0030322 // stabilization of membrane potential // inferred from direct assay /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0046541 // saliva secretion // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from direct assay /// 0071435 // potassium ion export // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0045121 // membrane raft // inferred from electronic annotation 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0022894 // Intermediate conductance calcium-activated potassium channel activity // not recorded 204402_at NM_012265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012265.1 /DEF=Homo sapiens chromosome 22 open reading frame 3 (C22ORF3), mRNA. /FEA=mRNA /GEN=C22ORF3 /PROD=chromosome 22 open reading frame 3 /DB_XREF=gi:11072100 /UG=Hs.106730 chromosome 22 open reading frame 3 /FL=gb:NM_012265.1 gb:BC002705.1 NM_012265 rhomboid domain containing 3 RHBDD3 25807 NM_012265 /// XM_005261504 /// XM_006724224 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204403_x_at NM_014719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014719.1 /DEF=Homo sapiens KIAA0738 gene product (KIAA0738), mRNA. /FEA=mRNA /GEN=KIAA0738 /PROD=KIAA0738 gene product /DB_XREF=gi:7662275 /UG=Hs.107479 KIAA0738 gene product /FL=gb:AB018281.1 gb:NM_014719.1 NM_014719 family with sequence similarity 115, member A /// protein FAM115A-like FAM115A /// LOC100294033 9747 /// 100294033 NM_001206938 /// NM_001206941 /// NM_014719 /// XM_003120061 /// XM_005250074 /// XM_005250075 /// XM_005250076 /// XM_005250077 /// XM_006716190 /// XM_006716191 /// XM_006716192 /// XM_006716193 204404_at NM_001046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001046.1 /DEF=Homo sapiens solute carrier family 12 (sodiumpotassiumchloride transporters), member 2 (SLC12A2), mRNA. /FEA=mRNA /GEN=SLC12A2 /PROD=solute carrier family 12(sodiumpotassiumchloride transporters), member 2 /DB_XREF=gi:4506974 /UG=Hs.110736 solute carrier family 12 (sodiumpotassiumchloride transporters), member 2 /FL=gb:NM_001046.1 gb:U30246.1 NM_001046 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 SLC12A2 6558 NM_001046 /// NM_001256461 /// NR_046207 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0015696 // ammonium transport // inferred from direct assay /// 0030321 // transepithelial chloride transport // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045795 // positive regulation of cell volume // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation /// 0070634 // transepithelial ammonium transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008511 // sodium:potassium:chloride symporter activity // inferred from electronic annotation /// 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation 204405_x_at NM_014473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014473.1 /DEF=Homo sapiens putative dimethyladenosine transferase (HSA9761), mRNA. /FEA=mRNA /GEN=HSA9761 /PROD=putative dimethyladenosine transferase /DB_XREF=gi:7657197 /UG=Hs.125819 putative dimethyladenosine transferase /FL=gb:AF102147.1 gb:NM_014473.1 NM_014473 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) DIMT1 27292 NM_014473 0000154 // rRNA modification // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016433 // rRNA (adenine) methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0052909 // 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity // inferred from electronic annotation 204406_at NM_002019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002019.1 /DEF=Homo sapiens fms-related tyrosine kinase 1 (vascular endothelial growth factorvascular permeability factor receptor) (FLT1), mRNA. /FEA=mRNA /GEN=FLT1 /PROD=fms-related tyrosine kinase 1 (vascularendothelial growth factorvascular permeability factorreceptor) /DB_XREF=gi:4503748 /UG=Hs.138671 fms-related tyrosine kinase 1 (vascular endothelial growth factorvascular permeability factor receptor) /FL=gb:AF063657.1 gb:NM_002019.1 NM_002019 fms-related tyrosine kinase 1 FLT1 2321 NM_001159920 /// NM_001160030 /// NM_001160031 /// NM_002019 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036323 // vascular endothelial growth factor receptor-1 signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048598 // embryonic morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0036326 // VEGF-A-activated receptor activity // inferred from direct assay /// 0036327 // VEGF-B-activated receptor activity // inferred from direct assay /// 0036332 // placental growth factor-activated receptor activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation 204407_at AF080255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080255.1 /DEF=Homo sapiens lodestar protein mRNA, complete cds. /FEA=mRNA /PROD=lodestar protein /DB_XREF=gi:5733121 /UG=Hs.142157 transcription termination factor, RNA polymerase II /FL=gb:AF073771.1 gb:NM_003594.1 gb:AF080255.1 AF080255 transcription termination factor, RNA polymerase II TTF2 8458 NM_003594 /// XM_005271277 /// XM_006710979 /// XM_006710980 /// XM_006710981 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008023 // transcription elongation factor complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204408_at NM_014481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014481.1 /DEF=Homo sapiens apurinicapyrimidinic endonuclease(APEX nuclease)-like 2 protein (APEXL2), mRNA. /FEA=mRNA /GEN=APEXL2 /PROD=apurinicapyrimidinic endonuclease(APEXnuclease)-like 2 protein /DB_XREF=gi:7656891 /UG=Hs.154149 apurinicapyrimidinic endonuclease(APEX nuclease)-like 2 protein /FL=gb:AB049211.1 gb:BC002959.1 gb:AB021260.1 gb:AF119046.1 gb:NM_014481.1 NM_014481 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 APEX2 27301 NM_001271748 /// NM_014481 0000737 // DNA catabolic process, endonucleolytic // not recorded /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // not recorded /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // not recorded /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008311 // double-stranded DNA 3'-5' exodeoxyribonuclease activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204409_s_at BC005248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005248.1 /DEF=Homo sapiens, clone MGC:12282, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12282) /DB_XREF=gi:13528902 /UG=Hs.155103 eukaryotic translation initiation factor 1A, Y chromosome /FL=gb:BC005248.1 gb:AF000987.1 gb:NM_004681.1 BC005248 eukaryotic translation initiation factor 1A, Y-linked EIF1AY 9086 NM_001278612 /// NM_004681 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204410_at NM_004681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004681.1 /DEF=Homo sapiens eukaryotic translation initiation factor 1A, Y chromosome (EIF1AY), mRNA. /FEA=mRNA /GEN=EIF1AY /PROD=eukaryotic translation initiation factor 1A, Ychromosome /DB_XREF=gi:4758253 /UG=Hs.155103 eukaryotic translation initiation factor 1A, Y chromosome /FL=gb:BC005248.1 gb:AF000987.1 gb:NM_004681.1 NM_004681 eukaryotic translation initiation factor 1A, Y-linked EIF1AY 9086 NM_001278612 /// NM_004681 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204411_at NM_017596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017596.1 /DEF=Homo sapiens KIAA0449 protein (KIAA0449), mRNA. /FEA=mRNA /GEN=KIAA0449 /PROD=hypothetical protein DKFZp434J212 /DB_XREF=gi:8922142 /UG=Hs.169182 KIAA0449 protein /FL=gb:NM_017596.1 NM_017596 kinesin family member 21B KIF21B 23046 NM_001252100 /// NM_001252102 /// NM_001252103 /// NM_017596 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 204412_s_at NM_021076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021076.1 /DEF=Homo sapiens neurofilament, heavy polypeptide (200kD) (NEFH), mRNA. /FEA=mRNA /GEN=NEFH /PROD=neurofilament, heavy polypeptide (200kD) /DB_XREF=gi:10835088 /UG=Hs.198760 neurofilament, heavy polypeptide (200kD) /FL=gb:NM_021076.1 gb:AF203032.1 NM_021076 neurofilament, heavy polypeptide NEFH 4744 NM_021076 /// XM_005261619 /// XM_006724257 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0030031 // cell projection assembly // traceable author statement /// 0033693 // neurofilament bundle assembly // inferred from mutant phenotype /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation /// 0061564 // axon development // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // non-traceable author statement /// 0030424 // axon // traceable author statement /// 0097418 // neurofibrillary tangle // inferred from direct assay 0005198 // structural molecule activity // inferred from mutant phenotype /// 0005200 // structural constituent of cytoskeleton // inferred from sequence or structural similarity /// 0008017 // microtubule binding // traceable author statement /// 0019894 // kinesin binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0045502 // dynein binding // traceable author statement 204413_at NM_021138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021138.1 /DEF=Homo sapiens TNF receptor-associated factor 2 (TRAF2), mRNA. /FEA=mRNA /GEN=TRAF2 /PROD=TNF receptor-associated factor 2 /DB_XREF=gi:10863938 /UG=Hs.200526 TNF receptor-associated factor 2 /FL=gb:NM_021138.1 gb:U12597.1 NM_021138 TNF receptor-associated factor 2 TRAF2 7186 NM_021138 /// XM_005266099 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034351 // negative regulation of glial cell apoptotic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // traceable author statement /// 0070207 // protein homotrimerization // inferred from physical interaction /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005174 // CD40 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046625 // sphingolipid binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204414_at NM_004737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004737.1 /DEF=Homo sapiens like-glycosyltransferase (LARGE), mRNA. /FEA=mRNA /GEN=LARGE /PROD=like-glycosyltransferase /DB_XREF=gi:4758663 /UG=Hs.25220 like-glycosyltransferase /FL=gb:NM_004737.1 NM_004737 like-glycosyltransferase LARGE 9215 NM_004737 /// NM_133642 /// XM_005261831 /// XM_005261832 /// XM_006724375 0006044 // N-acetylglucosamine metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // traceable author statement 204415_at NM_022873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022873.1 /DEF=Homo sapiens interferon, alpha-inducible protein (clone IFI-6-16) (G1P3), transcript variant 3, mRNA. /FEA=mRNA /GEN=G1P3 /PROD=interferon induced 6-16 protein, isoform c /DB_XREF=gi:13259549 /UG=Hs.265827 interferon, alpha-inducible protein (clone IFI-6-16) /FL=gb:NM_022872.1 gb:NM_022873.1 gb:NM_002038.2 NM_022873 interferon, alpha-inducible protein 6 IFI6 2537 NM_002038 /// NM_022872 /// NM_022873 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051902 // negative regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204416_x_at NM_001645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001645.2 /DEF=Homo sapiens apolipoprotein C-I (APOC1), mRNA. /FEA=mRNA /GEN=APOC1 /PROD=apolipoprotein C-I precursor /DB_XREF=gi:5174774 /UG=Hs.268571 apolipoprotein C-I /FL=gb:NM_001645.2 NM_001645 apolipoprotein C-I APOC1 341 NM_001645 /// XM_005258855 0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010873 // positive regulation of cholesterol esterification // traceable author statement /// 0010900 // negative regulation of phosphatidylcholine catabolic process // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0032374 // regulation of cholesterol transport // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034369 // plasma lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // traceable author statement /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from genetic interaction /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // traceable author statement /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // traceable author statement 204417_at NM_000153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000153.1 /DEF=Homo sapiens galactosylceramidase (Krabbe disease) (GALC), mRNA. /FEA=mRNA /GEN=GALC /PROD=galactosylceramidase precursor /DB_XREF=gi:4557612 /UG=Hs.273 galactosylceramidase (Krabbe disease) /FL=gb:L23116.1 gb:NM_000153.1 gb:D25283.1 NM_000153 galactosylceramidase GALC 2581 NM_000153 /// NM_001037525 /// NM_001201401 /// NM_001201402 /// XR_245677 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006683 // galactosylceramide catabolic process // inferred from sequence or structural similarity /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004336 // galactosylceramidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 204418_x_at NM_000848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000848.1 /DEF=Homo sapiens glutathione S-transferase M2 (muscle) (GSTM2), mRNA. /FEA=mRNA /GEN=GSTM2 /PROD=glutathione S-transferase M2 (muscle) /DB_XREF=gi:4504174 /UG=Hs.279837 glutathione S-transferase M2 (muscle) /FL=gb:M63509.1 gb:NM_000848.1 NM_000848 glutathione S-transferase mu 2 (muscle) GSTM2 2946 NM_000848 /// NM_001142368 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred by curator /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 204419_x_at NM_000184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000184.1 /DEF=Homo sapiens hemoglobin, gamma G (HBG2), mRNA. /FEA=mRNA /GEN=HBG2 /PROD=hemoglobin, gamma G /DB_XREF=gi:6715606 /UG=Hs.283108 hemoglobin, gamma G /FL=gb:NM_000184.1 NM_000184 hemoglobin, gamma A /// hemoglobin, gamma G HBG1 /// HBG2 3047 /// 3048 NM_000184 /// NM_000559 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204420_at BG251266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG251266 /FEA=EST /DB_XREF=gi:12761082 /DB_XREF=est:602365892F1 /CLONE=IMAGE:4474055 /UG=Hs.283565 FOS-like antigen-1 /FL=gb:NM_005438.1 BG251266 FOS-like antigen 1 FOSL1 8061 NM_005438 /// XM_005274311 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007296 // vitellogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0009629 // response to gravity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204421_s_at M27968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M27968.1 /DEF=Human basic fibroblast growth factor (FGF) mRNA, complete cds. /FEA=mRNA /GEN=FGF2 /DB_XREF=gi:182562 /UG=Hs.284244 fibroblast growth factor 2 (basic) /FL=gb:M27968.1 gb:NM_002006.1 M27968 fibroblast growth factor 2 (basic) FGF2 2247 NM_002006 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000189 // MAPK import into nucleus // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from direct assay /// 0001759 // organ induction // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from genetic interaction /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006700 // C21-steroid hormone biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010764 // negative regulation of fibroblast migration // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032958 // inositol phosphate biosynthetic process // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042660 // positive regulation of cell fate specification // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046668 // regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048598 // embryonic morphogenesis // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048864 // stem cell development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from electronic annotation /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060591 // chondroblast differentiation // inferred from direct assay /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay 204422_s_at NM_002006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002006.1 /DEF=Homo sapiens fibroblast growth factor 2 (basic) (FGF2), mRNA. /FEA=mRNA /GEN=FGF2 /PROD=fibroblast growth factor 2 (basic) /DB_XREF=gi:4503698 /UG=Hs.284244 fibroblast growth factor 2 (basic) /FL=gb:M27968.1 gb:NM_002006.1 NM_002006 fibroblast growth factor 2 (basic) FGF2 2247 NM_002006 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000189 // MAPK import into nucleus // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from direct assay /// 0001759 // organ induction // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from genetic interaction /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006700 // C21-steroid hormone biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010764 // negative regulation of fibroblast migration // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032958 // inositol phosphate biosynthetic process // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042660 // positive regulation of cell fate specification // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046668 // regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048598 // embryonic morphogenesis // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048864 // stem cell development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from electronic annotation /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060591 // chondroblast differentiation // inferred from direct assay /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay 204423_at NM_013255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013255.1 /DEF=Homo sapiens muskelin 1, intracellular mediator containing kelch motifs (MKLN1), mRNA. /FEA=mRNA /GEN=MKLN1 /PROD=muskelin 1, intracellular mediator containingkelch motifs /DB_XREF=gi:7019458 /UG=Hs.288791 muskelin 1, intracellular mediator containing kelch motifs /FL=gb:BC002834.1 gb:AF047489.1 gb:NM_013255.1 NM_013255 muskelin 1, intracellular mediator containing kelch motifs MKLN1 4289 NM_001145354 /// NM_013255 /// XM_005250355 /// XM_005250356 /// XM_006715992 /// XM_006715993 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204424_s_at AL050152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050152.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586K1220 (from clone DKFZp586K1220). /FEA=mRNA /DB_XREF=gi:4884363 /UG=Hs.301914 neuronal specific transcription factor DAT1 /FL=gb:AF258348.1 gb:NM_018640.1 AL050152 LIM domain only 3 (rhombotin-like 2) LMO3 55885 NM_001001395 /// NM_001243609 /// NM_001243610 /// NM_001243611 /// NM_001243612 /// NM_001243613 /// NM_018640 /// NR_045012 /// NR_045013 /// NR_045014 /// XM_006719110 /// XM_006719111 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204425_at NM_001666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001666.1 /DEF=Homo sapiens Rho GTPase activating protein 4 (ARHGAP4), mRNA. /FEA=mRNA /GEN=ARHGAP4 /PROD=Rho GTPase activating protein 4 /DB_XREF=gi:11386132 /UG=Hs.3109 Rho GTPase activating protein 4 /FL=gb:NM_001666.1 NM_001666 Rho GTPase activating protein 4 ARHGAP4 393 NM_001164741 /// NM_001666 0007010 // cytoskeleton organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010764 // negative regulation of fibroblast migration // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204426_at NM_006815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006815.1 /DEF=Homo sapiens coated vesicle membrane protein (RNP24), mRNA. /FEA=mRNA /GEN=RNP24 /PROD=coated vesicle membrane protein /DB_XREF=gi:5803148 /UG=Hs.323378 coated vesicle membrane protein /FL=gb:NM_006815.1 NM_006815 transmembrane emp24 domain trafficking protein 2 TMED2 10959 NM_006815 /// XM_005253544 0001893 // maternal placenta development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0035459 // cargo loading into vesicle // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204427_s_at NM_006815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006815.1 /DEF=Homo sapiens coated vesicle membrane protein (RNP24), mRNA. /FEA=mRNA /GEN=RNP24 /PROD=coated vesicle membrane protein /DB_XREF=gi:5803148 /UG=Hs.323378 coated vesicle membrane protein /FL=gb:NM_006815.1 NM_006815 transmembrane emp24 domain trafficking protein 2 TMED2 10959 NM_006815 /// XM_005253544 0001893 // maternal placenta development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0035459 // cargo loading into vesicle // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204428_s_at NM_000229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000229.1 /DEF=Homo sapiens lecithin-cholesterol acyltransferase (LCAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=LCAT /PROD=lecithin-cholesterol acyltransferase precursor /DB_XREF=gi:4557891 /UG=Hs.325507 lecithin-cholesterol acyltransferase /FL=gb:M12625.1 gb:NM_000229.1 NM_000229 lecithin-cholesterol acyltransferase LCAT 3931 NM_000229 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0030301 // cholesterol transport // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from direct assay /// 0034435 // cholesterol esterification // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0090107 // regulation of high-density lipoprotein particle assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004607 // phosphatidylcholine-sterol O-acyltransferase activity // inferred from direct assay /// 0004607 // phosphatidylcholine-sterol O-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction 204429_s_at BE560461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE560461 /FEA=EST /DB_XREF=gi:9804181 /DB_XREF=est:601346729F1 /CLONE=IMAGE:3687631 /UG=Hs.33084 solute carrier family 2 (facilitated glucose transporter), member 5 /FL=gb:BC001820.1 gb:BC001692.1 gb:M55531.1 gb:NM_003039.1 BE560461 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 SLC2A5 6518 NM_001135585 /// NM_003039 /// NR_024180 /// XM_005263491 /// XM_006710836 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015755 // fructose transport // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071332 // cellular response to fructose stimulus // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005353 // fructose transmembrane transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 204430_s_at NM_003039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003039.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 5 (SLC2A5), mRNA. /FEA=mRNA /GEN=SLC2A5 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 5 /DB_XREF=gi:4507012 /UG=Hs.33084 solute carrier family 2 (facilitated glucose transporter), member 5 /FL=gb:BC001820.1 gb:BC001692.1 gb:M55531.1 gb:NM_003039.1 NM_003039 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 SLC2A5 6518 NM_001135585 /// NM_003039 /// NR_024180 /// XM_005263491 /// XM_006710836 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015755 // fructose transport // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071332 // cellular response to fructose stimulus // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005353 // fructose transmembrane transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 204431_at NM_003260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003260.1 /DEF=Homo sapiens transducin-like enhancer of split 2, homolog of Drosophila E(sp1) (TLE2), mRNA. /FEA=mRNA /GEN=TLE2 /PROD=transducin-like enhancer of split 2, homolog ofDrosophila E(sp1) /DB_XREF=gi:4507522 /UG=Hs.332173 transducin-like enhancer of split 2, homolog of Drosophila E(sp1) /FL=gb:M99436.1 gb:NM_003260.1 NM_003260 transducin-like enhancer of split 2 TLE2 7089 NM_001144761 /// NM_001144762 /// NM_003260 /// XM_005259636 /// XM_005259637 /// XM_006722864 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204432_at NM_006943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006943.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 22 (SOX22), mRNA. /FEA=mRNA /GEN=SOX22 /PROD=SRY (sex determining region Y)-box 22 /DB_XREF=gi:5902109 /UG=Hs.43627 SRY (sex determining region Y)-box 22 /FL=gb:U35612.1 gb:NM_006943.1 NM_006943 SRY (sex determining region Y)-box 12 SOX12 6666 NM_006943 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // non-traceable author statement 204433_s_at U28164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U28164.1 /DEF=Homo sapiens spermatogenesis associated PD1 mRNA, complete cds. /FEA=mRNA /PROD=spermatogenesis associated PD1 /DB_XREF=gi:4730926 /UG=Hs.48513 spermatogenesis associated 2 /FL=gb:AB018300.1 gb:U28164.1 gb:NM_006038.1 U28164 spermatogenesis associated 2 SPATA2 9825 NM_001135773 /// NM_006038 /// XM_006723894 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 204434_at NM_006038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006038.1 /DEF=Homo sapiens spermatogenesis associated PD1 (KIAA0757), mRNA. /FEA=mRNA /GEN=KIAA0757 /PROD=spermatogenesis associated PD1 /DB_XREF=gi:5174486 /UG=Hs.48513 spermatogenesis associated 2 /FL=gb:AB018300.1 gb:U28164.1 gb:NM_006038.1 NM_006038 spermatogenesis associated 2 SPATA2 9825 NM_001135773 /// NM_006038 /// XM_006723894 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 204435_at NM_014778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014778.1 /DEF=Homo sapiens KIAA0410 gene product (KIAA0410), mRNA. /FEA=mRNA /GEN=KIAA0410 /PROD=KIAA0410 gene product /DB_XREF=gi:7662097 /UG=Hs.55075 KIAA0410 gene product /FL=gb:AB007870.1 gb:NM_014778.1 NM_014778 nucleoporin like 1 NUPL1 9818 NM_001008564 /// NM_001008565 /// NM_014089 /// XM_005266600 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204436_at NM_025201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025201.1 /DEF=Homo sapiens hypothetical protein PP1628 (PP1628), mRNA. /FEA=mRNA /GEN=PP1628 /PROD=hypothetical protein PP1628 /DB_XREF=gi:13376795 /UG=Hs.7159 hypothetical protein PP1628 /FL=gb:NM_025201.1 NM_025201 pleckstrin homology domain containing, family O member 2 PLEKHO2 80301 NM_001195059 /// NM_025201 0005543 // phospholipid binding // inferred from electronic annotation 204437_s_at NM_016725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016725.1 /DEF=Homo sapiens folate receptor 1 (adult) (FOLR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=FOLR1 /PROD=folate receptor 1 precursor /DB_XREF=gi:9257206 /UG=Hs.73769 folate receptor 1 (adult) /FL=gb:NM_000802.2 gb:NM_016731.2 gb:BC002947.1 gb:J05013.1 gb:NM_016725.1 gb:NM_016729.1 NM_016725 folate receptor 1 (adult) FOLR1 2348 NM_000802 /// NM_016724 /// NM_016725 /// NM_016729 /// NM_016730 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from mutant phenotype /// 0046655 // folic acid metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005542 // folic acid binding // inferred from direct assay /// 0005542 // folic acid binding // non-traceable author statement /// 0008517 // folic acid transporter activity // inferred from mutant phenotype 204438_at NM_002438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002438.1 /DEF=Homo sapiens mannose receptor, C type 1 (MRC1), mRNA. /FEA=mRNA /GEN=MRC1 /PROD=mannose receptor, C type 1 /DB_XREF=gi:4505244 /UG=Hs.75182 mannose receptor, C type 1 /FL=gb:J05550.1 gb:NM_002438.1 NM_002438 mannose receptor, C type 1 MRC1 4360 NM_001009567 /// NM_002438 /// XM_006726512 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 204439_at NM_006820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006820.1 /DEF=Homo sapiens hypothetical protein, expressed in osteoblast (GS3686), mRNA. /FEA=mRNA /GEN=GS3686 /PROD=hypothetical protein, expressed in osteoblast /DB_XREF=gi:5803026 /UG=Hs.75470 hypothetical protein, expressed in osteoblast /FL=gb:AB000115.1 gb:NM_006820.1 NM_006820 interferon-induced protein 44-like IFI44L 10964 NM_006820 /// XM_005270391 /// XM_005270392 /// XM_005270393 /// XM_006710303 /// XM_006710304 0006955 // immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 204440_at NM_004233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004233.1 /DEF=Homo sapiens CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) (CD83), mRNA. /FEA=mRNA /GEN=CD83 /PROD=CD83 antigen (activated B lymphocytes,immunoglobulin superfamily) /DB_XREF=gi:4757945 /UG=Hs.79197 CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) /FL=gb:NM_004233.1 NM_004233 CD83 molecule CD83 9308 NM_001040280 /// NM_001251901 /// NM_004233 0006952 // defense response // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032713 // negative regulation of interleukin-4 production // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from electronic annotation /// 0043372 // positive regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204441_s_at NM_002689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002689.1 /DEF=Homo sapiens polymerase (DNA-directed), alpha (70kD) (POLA2), mRNA. /FEA=mRNA /GEN=POLA2 /PROD=polymerase (DNA-directed), alpha (70kD) /DB_XREF=gi:4505928 /UG=Hs.81942 polymerase (DNA-directed), alpha (70kD) /FL=gb:BC001347.1 gb:BC002990.1 gb:L24559.1 gb:NM_002689.1 NM_002689 polymerase (DNA directed), alpha 2, accessory subunit POLA2 23649 NM_002689 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // not recorded /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005658 // alpha DNA polymerase:primase complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // not recorded 204442_x_at NM_003573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003573.1 /DEF=Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), mRNA. /FEA=mRNA /GEN=LTBP4 /PROD=latent transforming growth factor beta bindingprotein 4 /DB_XREF=gi:4505036 /UG=Hs.85087 latent transforming growth factor beta binding protein 4 /FL=gb:NM_003573.1 NM_003573 latent transforming growth factor beta binding protein 4 LTBP4 8425 NM_001042544 /// NM_001042545 /// NM_003573 0001558 // regulation of cell growth // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016049 // cell growth // traceable author statement /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030162 // regulation of proteolysis // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030252 // growth hormone secretion // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0046879 // hormone secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // non-traceable author statement /// 0008083 // growth factor activity // non-traceable author statement /// 0008083 // growth factor activity // traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 204443_at NM_000487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000487.3 /DEF=Homo sapiens arylsulfatase A (ARSA), mRNA. /FEA=mRNA /GEN=ARSA /PROD=arylsulfatase A precursor /DB_XREF=gi:7262293 /UG=Hs.88251 arylsulfatase A /FL=gb:X52151.1 gb:NM_000487.3 NM_000487 arylsulfatase A ARSA 410 NM_000487 /// NM_001085425 /// NM_001085426 /// NM_001085427 /// NM_001085428 /// XM_006724414 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // inferred from electronic annotation /// 0004098 // cerebroside-sulfatase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204444_at NM_004523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004523.2 /DEF=Homo sapiens kinesin-like 1 (KNSL1), mRNA. /FEA=mRNA /GEN=KNSL1 /PROD=kinesin-like 1 /DB_XREF=gi:13699823 /UG=Hs.8878 kinesin-like 1 /FL=gb:U37426.1 gb:NM_004523.2 NM_004523 kinesin family member 11 KIF11 3832 NM_004523 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007100 // mitotic centrosome separation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay 204445_s_at AI361850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI361850 /FEA=EST /DB_XREF=gi:4113471 /DB_XREF=est:qz25a02.x1 /CLONE=IMAGE:2027882 /UG=Hs.89499 arachidonate 5-lipoxygenase /FL=gb:J03600.1 gb:J03571.1 gb:NM_000698.1 AI361850 arachidonate 5-lipoxygenase ALOX5 240 NM_000698 /// NM_001256153 /// NM_001256154 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0004051 // arachidonate 5-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 204446_s_at NM_000698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000698.1 /DEF=Homo sapiens arachidonate 5-lipoxygenase (ALOX5), mRNA. /FEA=mRNA /GEN=ALOX5 /PROD=arachidonate 5-lipoxygenase /DB_XREF=gi:4502056 /UG=Hs.89499 arachidonate 5-lipoxygenase /FL=gb:J03600.1 gb:J03571.1 gb:NM_000698.1 NM_000698 arachidonate 5-lipoxygenase ALOX5 240 NM_000698 /// NM_001256153 /// NM_001256154 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0004051 // arachidonate 5-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 204447_at NM_014731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014731.1 /DEF=Homo sapiens KIAA0552 gene product (KIAA0552), mRNA. /FEA=mRNA /GEN=KIAA0552 /PROD=KIAA0552 gene product /DB_XREF=gi:7662175 /UG=Hs.90232 KIAA0552 gene product /FL=gb:AB011124.1 gb:NM_014731.1 NM_014731 leucine zipper, putative tumor suppressor family member 3 LZTS3 9762 NM_001282533 /// NM_014731 /// XM_005260890 /// XM_005260891 /// XM_005260892 /// XM_005260893 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 204448_s_at AF031463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031463.1 /DEF=Homo sapiens phosducin-like protein mRNA, complete cds. /FEA=mRNA /PROD=phosducin-like protein /DB_XREF=gi:4104074 /UG=Hs.9302 phosducin-like /FL=gb:AF031463.1 gb:AL117602.1 gb:NM_005388.2 AF031463 phosducin-like PDCL 5082 NM_005388 0006457 // protein folding // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061084 // negative regulation of protein refolding // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005057 // receptor signaling protein activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation 204449_at NM_005388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005388.2 /DEF=Homo sapiens phosducin-like (PDCL), mRNA. /FEA=mRNA /GEN=PDCL /PROD=phosducin-like /DB_XREF=gi:9943841 /UG=Hs.9302 phosducin-like /FL=gb:AF031463.1 gb:AL117602.1 gb:NM_005388.2 NM_005388 phosducin-like PDCL 5082 NM_005388 0006457 // protein folding // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061084 // negative regulation of protein refolding // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005057 // receptor signaling protein activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation 204450_x_at NM_000039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000039.1 /DEF=Homo sapiens apolipoprotein A-I (APOA1), mRNA. /FEA=mRNA /GEN=APOA1 /PROD=apolipoprotein A-I precursor /DB_XREF=gi:4557320 /UG=Hs.93194 apolipoprotein A-I /FL=gb:BC005380.1 gb:M27875.1 gb:M11791.1 gb:NM_000039.1 NM_000039 apolipoprotein A-I APOA1 335 NM_000039 /// XM_005271539 /// XM_005271540 0001523 // retinoid metabolic process // traceable author statement /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0019915 // lipid storage // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from direct assay /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred by curator /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred by curator /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050713 // negative regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051345 // positive regulation of hydrolase activity // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055091 // phospholipid homeostasis // inferred from direct assay /// 0060192 // negative regulation of lipase activity // inferred from electronic annotation /// 0060354 // negative regulation of cell adhesion molecule production // inferred from direct assay /// 0060761 // negative regulation of response to cytokine stimulus // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from direct assay /// 0070508 // cholesterol import // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005548 // phospholipid transporter activity // inferred from electronic annotation /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0034190 // apolipoprotein receptor binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from electronic annotation /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070653 // high-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 204451_at NM_003505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003505.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 1 (FZD1), mRNA. /FEA=mRNA /GEN=FZD1 /PROD=frizzled 1 /DB_XREF=gi:4503824 /UG=Hs.94234 frizzled (Drosophila) homolog 1 /FL=gb:AB017363.1 gb:NM_003505.1 gb:AF072872.1 NM_003505 frizzled class receptor 1 FZD1 8321 NM_003505 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003150 // muscular septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // not recorded /// 0030855 // epithelial cell differentiation // not recorded /// 0035414 // negative regulation of catenin import into nucleus // inferred from electronic annotation /// 0035425 // autocrine signaling // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0044338 // canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation // inferred from mutant phenotype /// 0044339 // canonical Wnt signaling pathway involved in osteoblast differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048286 // lung alveolus development // not recorded /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060022 // hard palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // inferred from direct assay 204452_s_at AF072872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072872.1 /DEF=Homo sapiens frizzled 1 mRNA, complete cds. /FEA=mRNA /PROD=frizzled 1 /DB_XREF=gi:5305406 /UG=Hs.94234 frizzled (Drosophila) homolog 1 /FL=gb:AB017363.1 gb:NM_003505.1 gb:AF072872.1 AF072872 frizzled class receptor 1 FZD1 8321 NM_003505 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003150 // muscular septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // not recorded /// 0030855 // epithelial cell differentiation // not recorded /// 0035414 // negative regulation of catenin import into nucleus // inferred from electronic annotation /// 0035425 // autocrine signaling // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0044338 // canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation // inferred from mutant phenotype /// 0044339 // canonical Wnt signaling pathway involved in osteoblast differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048286 // lung alveolus development // not recorded /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060022 // hard palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // inferred from direct assay 204453_at NM_003428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003428.1 /DEF=Homo sapiens zinc finger protein 84 (HPF2) (ZNF84), mRNA. /FEA=mRNA /GEN=ZNF84 /PROD=zinc finger protein 84 (HPF2) /DB_XREF=gi:4508036 /UG=Hs.9450 zinc finger protein 84 (HPF2) /FL=gb:M27878.1 gb:NM_003428.1 NM_003428 zinc finger protein 84 ZNF84 7637 NM_001127372 /// NM_001289971 /// NM_001289972 /// NM_003428 /// XM_005266184 /// XM_005266185 /// XM_005266186 /// XM_006719747 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204454_at NM_012317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012317.1 /DEF=Homo sapiens leucine zipper, down-regulated in cancer 1 (LDOC1), mRNA. /FEA=mRNA /GEN=LDOC1 /PROD=leucine zipper, down-regulated in cancer 1 /DB_XREF=gi:6912479 /UG=Hs.45231 leucine zipper, down-regulated in cancer 1 /FL=gb:BC003104.1 gb:AB019527.1 gb:NM_012317.1 NM_012317 leucine zipper, down-regulated in cancer 1 LDOC1 23641 NM_012317 0008285 // negative regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204455_at NM_001723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001723.1 /DEF=Homo sapiens bullous pemphigoid antigen 1 (230240kD) (BPAG1), mRNA. /FEA=mRNA /GEN=BPAG1 /PROD=bullous pemphigoid antigen 1 (230240kD) /DB_XREF=gi:4502442 /UG=Hs.620 bullous pemphigoid antigen 1 (230240kD) /FL=gb:M63618.1 gb:M69225.1 gb:L11690.1 gb:NM_001723.1 NM_001723 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 204456_s_at AW611727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW611727 /FEA=EST /DB_XREF=gi:7316913 /DB_XREF=est:hg86h08.x1 /CLONE=IMAGE:2952543 /UG=Hs.65029 growth arrest-specific 1 /FL=gb:NM_002048.1 gb:L13698.1 AW611727 growth arrest-specific 1 GAS1 2619 NM_002048 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from mutant phenotype /// 0012501 // programmed cell death // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from expression pattern /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from genetic interaction /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0048592 // eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 204457_s_at NM_002048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002048.1 /DEF=Homo sapiens growth arrest-specific 1 (GAS1), mRNA. /FEA=mRNA /GEN=GAS1 /PROD=growth arrest-specific 1 /DB_XREF=gi:4503918 /UG=Hs.65029 growth arrest-specific 1 /FL=gb:NM_002048.1 gb:L13698.1 NM_002048 growth arrest-specific 1 GAS1 2619 NM_002048 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from mutant phenotype /// 0012501 // programmed cell death // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from expression pattern /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from genetic interaction /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0048592 // eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 204458_at AL110209 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110209.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A0122 (from clone DKFZp564A0122); partial cds. /FEA=mRNA /GEN=DKFZp564A0122 /PROD=hypothetical protein /DB_XREF=gi:5817129 /UG=Hs.6770 LCAT-like lysophospholipase /FL=gb:AB017494.1 gb:NM_012320.1 AL110209 phospholipase A2, group XV PLA2G15 23659 NM_012320 /// XM_005255886 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006672 // ceramide metabolic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // traceable author statement /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004622 // lysophospholipase activity // traceable author statement /// 0005543 // phospholipid binding // traceable author statement /// 0008374 // O-acyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from sequence or structural similarity 204459_at NM_001325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001325.1 /DEF=Homo sapiens cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kD (CSTF2), mRNA. /FEA=mRNA /GEN=CSTF2 /PROD=cleavage stimulation factor subunit 2 /DB_XREF=gi:4557492 /UG=Hs.693 cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kD /FL=gb:M85085.1 gb:NM_001325.1 NM_001325 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa CSTF2 1478 NM_001325 /// XM_006724622 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0071920 // cleavage body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204460_s_at AF074717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074717.1 /DEF=Homo sapiens Rad1-like DNA damage checkpoint protein (RAD1) mRNA, complete cds. /FEA=mRNA /GEN=RAD1 /PROD=Rad1-like DNA damage checkpoint protein /DB_XREF=gi:3309650 /UG=Hs.7179 RAD1 (S. pombe) homolog /FL=gb:AF058392.1 gb:AF073524.1 gb:AF074717.1 gb:AF011905.1 gb:AF084512.1 gb:AF030933.1 gb:AF076841.1 gb:NM_002853.1 AF074717 RAD1 homolog (S. pombe) RAD1 5810 NM_001033673 /// NM_002853 /// NM_133282 /// NM_133377 /// NR_026591 0000075 // cell cycle checkpoint // non-traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007128 // meiotic prophase I // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003684 // damaged DNA binding // non-traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204461_x_at NM_002853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002853.1 /DEF=Homo sapiens RAD1 (S. pombe) homolog (RAD1), mRNA. /FEA=mRNA /GEN=RAD1 /PROD=RAD1 (S. pombe) homolog /DB_XREF=gi:4506384 /UG=Hs.7179 RAD1 (S. pombe) homolog /FL=gb:AF058392.1 gb:AF073524.1 gb:AF074717.1 gb:AF011905.1 gb:AF084512.1 gb:AF030933.1 gb:AF076841.1 gb:NM_002853.1 NM_002853 RAD1 homolog (S. pombe) RAD1 5810 NM_001033673 /// NM_002853 /// NM_133282 /// NM_133377 /// NR_026591 0000075 // cell cycle checkpoint // non-traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007128 // meiotic prophase I // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003684 // damaged DNA binding // non-traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204462_s_at NM_006517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006517.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 2 (putative transporter) (SLC16A2), mRNA. /FEA=mRNA /GEN=SLC16A2 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 2 (putative transporter) /DB_XREF=gi:5730044 /UG=Hs.75317 solute carrier family 16 (monocarboxylic acid transporters), member 2 (putative transporter) /FL=gb:NM_006517.1 NM_006517 solute carrier family 16, member 2 (thyroid hormone transporter) SLC16A2 6567 NM_006517 /// XM_005262294 0006810 // transport // traceable author statement /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 204463_s_at AU118882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU118882 /FEA=EST /DB_XREF=gi:10934117 /DB_XREF=est:AU118882 /CLONE=HEMBA1004569 /UG=Hs.76252 endothelin receptor type A /FL=gb:L06622.1 gb:NM_001957.1 AU118882 endothelin receptor type A EDNRA 1909 NM_001166055 /// NM_001256283 /// NM_001957 /// NR_045958 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0003094 // glomerular filtration // inferred from electronic annotation /// 0006939 // smooth muscle contraction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from sequence or structural similarity /// 0008152 // metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014824 // artery smooth muscle contraction // inferred from mutant phenotype /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048659 // smooth muscle cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 0090184 // positive regulation of kidney development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204464_s_at NM_001957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001957.1 /DEF=Homo sapiens endothelin receptor type A (EDNRA), mRNA. /FEA=mRNA /GEN=EDNRA /PROD=endothelin receptor type A /DB_XREF=gi:4503464 /UG=Hs.76252 endothelin receptor type A /FL=gb:L06622.1 gb:NM_001957.1 NM_001957 endothelin receptor type A EDNRA 1909 NM_001166055 /// NM_001256283 /// NM_001957 /// NR_045958 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0003094 // glomerular filtration // inferred from electronic annotation /// 0006939 // smooth muscle contraction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from sequence or structural similarity /// 0008152 // metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014824 // artery smooth muscle contraction // inferred from mutant phenotype /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048659 // smooth muscle cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 0090184 // positive regulation of kidney development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204465_s_at NM_004692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004692.1 /DEF=Homo sapiens internexin neuronal intermediate filament protein, alpha (INA), mRNA. /FEA=mRNA /GEN=INA /PROD=internexin neuronal intermediate filamentprotein, alpha /DB_XREF=gi:4758607 /UG=Hs.76888 internexin neuronal intermediate filament protein, alpha /FL=gb:NM_004692.1 NM_004692 internexin neuronal intermediate filament protein, alpha INA 9118 NM_032727 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204466_s_at BG260394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG260394 /FEA=EST /DB_XREF=gi:12770210 /DB_XREF=est:602371523F1 /CLONE=IMAGE:4479556 /UG=Hs.76930 synuclein, alpha (non A4 component of amyloid precursor) /FL=gb:L08850.1 gb:NM_000345.2 BG260394 synuclein, alpha (non A4 component of amyloid precursor) SNCA 6622 NM_000345 /// NM_001146054 /// NM_001146055 /// NM_007308 0001774 // microglial cell activation // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006638 // neutral lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from direct assay /// 0010517 // regulation of phospholipase activity // inferred from direct assay /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014048 // regulation of glutamate secretion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032769 // negative regulation of monooxygenase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from direct assay /// 0045920 // negative regulation of exocytosis // inferred from mutant phenotype /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050812 // regulation of acyl-CoA biosynthetic process // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051583 // dopamine uptake involved in synaptic transmission // traceable author statement /// 0051585 // negative regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0051612 // negative regulation of serotonin uptake // inferred from direct assay /// 0051622 // negative regulation of norepinephrine uptake // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0070495 // negative regulation of thrombin receptor signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043205 // fibril // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from direct assay /// 0060961 // phospholipase D inhibitor activity // inferred from direct assay 204467_s_at NM_000345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000345.2 /DEF=Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant NACP140, mRNA. /FEA=mRNA /GEN=SNCA /PROD=alpha-synuclein isoform NACP140 /DB_XREF=gi:6806896 /UG=Hs.76930 synuclein, alpha (non A4 component of amyloid precursor) /FL=gb:L08850.1 gb:NM_000345.2 NM_000345 synuclein, alpha (non A4 component of amyloid precursor) SNCA 6622 NM_000345 /// NM_001146054 /// NM_001146055 /// NM_007308 0001774 // microglial cell activation // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006638 // neutral lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from direct assay /// 0010517 // regulation of phospholipase activity // inferred from direct assay /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014048 // regulation of glutamate secretion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032769 // negative regulation of monooxygenase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from direct assay /// 0045920 // negative regulation of exocytosis // inferred from mutant phenotype /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050812 // regulation of acyl-CoA biosynthetic process // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051583 // dopamine uptake involved in synaptic transmission // traceable author statement /// 0051585 // negative regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0051612 // negative regulation of serotonin uptake // inferred from direct assay /// 0051622 // negative regulation of norepinephrine uptake // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0070495 // negative regulation of thrombin receptor signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043205 // fibril // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from direct assay /// 0060961 // phospholipase D inhibitor activity // inferred from direct assay 204468_s_at NM_005424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005424.1 /DEF=Homo sapiens tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (TIE), mRNA. /FEA=mRNA /GEN=TIE /PROD=tyrosine kinase with immunoglobulin andepidermal growth factor homology domains /DB_XREF=gi:4885630 /UG=Hs.78824 tyrosine kinase with immunoglobulin and epidermal growth factor homology domains /FL=gb:NM_005424.1 NM_005424 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 TIE1 7075 NM_001253357 /// NM_005424 /// XM_005271163 /// XM_005271164 /// XM_006710869 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0045026 // plasma membrane fusion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204469_at NM_002851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002851.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1), mRNA. /FEA=mRNA /GEN=PTPRZ1 /PROD=protein tyrosine phosphatase, receptor-type, Zpolypeptide 1 /DB_XREF=gi:4506328 /UG=Hs.78867 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 /FL=gb:M93426.1 gb:NM_002851.1 NM_002851 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 PTPRZ1 5803 NM_001206838 /// NM_001206839 /// NM_002851 /// XM_005250519 /// XM_006716076 0006470 // protein dephosphorylation // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0070445 // regulation of oligodendrocyte progenitor proliferation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0072534 // perineuronal net // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from sequence or structural similarity /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008330 // protein tyrosine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 204470_at NM_001511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001511.1 /DEF=Homo sapiens GRO1 oncogene (melanoma growth stimulating activity, alpha) (GRO1), mRNA. /FEA=mRNA /GEN=GRO1 /PROD=GRO1 oncogene (melanoma growth stimulatingactivity, alpha) /DB_XREF=gi:4504152 /UG=Hs.789 GRO1 oncogene (melanoma growth stimulating activity, alpha) /FL=gb:NM_001511.1 NM_001511 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) CXCL1 2919 NM_001511 /// NR_046035 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 204471_at NM_002045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002045.1 /DEF=Homo sapiens growth associated protein 43 (GAP43), mRNA. /FEA=mRNA /GEN=GAP43 /PROD=growth associated protein 43 /DB_XREF=gi:4503910 /UG=Hs.79000 growth associated protein 43 /FL=gb:M25667.1 gb:NM_002045.1 NM_002045 growth associated protein 43 GAP43 2596 NM_001130064 /// NM_002045 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0016198 // axon choice point recognition // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 204472_at NM_005261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005261.1 /DEF=Homo sapiens GTP-binding protein overexpressed in skeletal muscle (GEM), mRNA. /FEA=mRNA /GEN=GEM /PROD=GTP-binding protein overexpressed in skeletalmuscle /DB_XREF=gi:4885262 /UG=Hs.79022 GTP-binding protein overexpressed in skeletal muscle /FL=gb:NM_005261.1 gb:U13052.1 gb:U10550.1 NM_005261 GTP binding protein overexpressed in skeletal muscle GEM 2669 NM_005261 /// NM_181702 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from mutant phenotype /// 0051310 // metaphase plate congression // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 204473_s_at NM_014630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014630.1 /DEF=Homo sapiens KIAA0211 gene product (KIAA0211), mRNA. /FEA=mRNA /GEN=KIAA0211 /PROD=KIAA0211 gene product /DB_XREF=gi:7661999 /UG=Hs.79347 KIAA0211 gene product /FL=gb:D86966.1 gb:NM_014630.1 NM_014630 zinc finger protein 592 ZNF592 9640 NM_014630 /// XM_005254996 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204474_at NM_005081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005081.1 /DEF=Homo sapiens zinc finger protein 142 (clone pHZ-49) (ZNF142), mRNA. /FEA=mRNA /GEN=ZNF142 /PROD=zinc finger protein 142 (clone pHZ-49) /DB_XREF=gi:4827062 /UG=Hs.80526 zinc finger protein 142 (clone pHZ-49) /FL=gb:D87073.1 gb:NM_005081.1 NM_005081 zinc finger protein 142 ZNF142 7701 NM_001105537 /// NM_005081 /// NR_073599 /// NR_073600 /// XM_006712730 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204475_at NM_002421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002421.2 /DEF=Homo sapiens matrix metalloproteinase 1 (interstitial collagenase) (MMP1), mRNA. /FEA=mRNA /GEN=MMP1 /PROD=matrix metalloproteinase 1 preproprotein /DB_XREF=gi:13027798 /UG=Hs.83169 matrix metalloproteinase 1 (interstitial collagenase) /FL=gb:NM_002421.2 gb:M13509.1 NM_002421 matrix metallopeptidase 1 (interstitial collagenase) MMP1 4312 NM_001145938 /// NM_002421 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204476_s_at NM_022172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022172.1 /DEF=Homo sapiens pyruvate carboxylase (PC), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA. /FEA=mRNA /GEN=PC /PROD=pyruvate carboxylase precursor /DB_XREF=gi:11761614 /UG=Hs.89890 pyruvate carboxylase /FL=gb:U30891.1 gb:NM_022172.1 gb:U04641.1 NM_022172 pyruvate carboxylase PC 5091 NM_000920 /// NM_001040716 /// NM_022172 /// XM_005274031 /// XM_005274032 /// XM_006718577 /// XM_006718578 /// XM_006718579 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0004736 // pyruvate carboxylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204477_at U74324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U74324.1 /DEF=Human guanine nucleotide exchange factor mss4 mRNA, complete cds. /FEA=mRNA /PROD=guanine nucleotide exchange factor mss4 /DB_XREF=gi:1658190 /UG=Hs.90875 RAB interacting factor /FL=gb:U74324.1 gb:NM_002871.1 U74324 RAB interacting factor RABIF 5877 NM_002871 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204478_s_at NM_002871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002871.1 /DEF=Homo sapiens RAB interacting factor (RABIF), mRNA. /FEA=mRNA /GEN=RABIF /PROD=RAB interacting factor /DB_XREF=gi:4506378 /UG=Hs.90875 RAB interacting factor /FL=gb:U74324.1 gb:NM_002871.1 NM_002871 RAB interacting factor RABIF 5877 NM_002871 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204479_at NM_012383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012383.1 /DEF=Homo sapiens osteoclast stimulating factor 1 (OSTF1), mRNA. /FEA=mRNA /GEN=OSTF1 /PROD=osteoclast stimulating factor 1 /DB_XREF=gi:6912563 /UG=Hs.95821 osteoclast stimulating factor 1 /FL=gb:U63717.1 gb:NM_012383.1 NM_012383 osteoclast stimulating factor 1 OSTF1 26578 NM_012383 /// XM_006717053 /// XM_006717054 /// XM_006717055 0001503 // ossification // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 204480_s_at NM_024112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024112.1 /DEF=Homo sapiens hypothetical protein EST00098 (EST00098), mRNA. /FEA=mRNA /GEN=EST00098 /PROD=hypothetical protein EST00098 /DB_XREF=gi:13129127 /UG=Hs.95867 hypothetical protein EST00098 /FL=gb:BC001857.1 gb:NM_024112.1 NM_024112 chromosome 9 open reading frame 16 C9orf16 79095 NM_024112 204481_at NM_004634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004634.1 /DEF=Homo sapiens bromodomain and PHD finger containing, 1 (BRPF1), mRNA. /FEA=mRNA /GEN=BRPF1 /PROD=bromodomain-containing protein /DB_XREF=gi:4757865 /UG=Hs.1004 bromodomain and PHD finger containing, 1 /FL=gb:M91585.1 gb:NM_004634.1 NM_004634 bromodomain and PHD finger containing, 1 BRPF1 7862 NM_001003694 /// NM_004634 /// XM_005265449 /// XM_005265450 /// XM_005265451 /// XM_005265452 /// XM_005265453 /// XM_005265454 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204482_at NM_003277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003277.1 /DEF=Homo sapiens claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) (CLDN5), mRNA. /FEA=mRNA /GEN=CLDN5 /PROD=transmembrane protein claudin 5 /DB_XREF=gi:4502878 /UG=Hs.110903 claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) /FL=gb:BC002404.1 gb:AF000959.1 gb:NM_003277.1 NM_003277 claudin 5 CLDN5 7122 NM_001130861 /// NM_003277 /// XM_005261272 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 204483_at NM_001976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001976.1 /DEF=Homo sapiens enolase 3, (beta, muscle) (ENO3), mRNA. /FEA=mRNA /GEN=ENO3 /PROD=enolase 3, (beta, muscle) /DB_XREF=gi:4503572 /UG=Hs.118804 enolase 3, (beta, muscle) /FL=gb:NM_001976.1 NM_001976 enolase 3 (beta, muscle) ENO3 2027 NM_001193503 /// NM_001976 /// NM_053013 /// XM_005256521 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042493 // response to drug // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204484_at NM_002646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002646.1 /DEF=Homo sapiens phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B), mRNA. /FEA=mRNA /GEN=PIK3C2B /PROD=phosphoinositide-3-kinase, class 2, betapolypeptide /DB_XREF=gi:11136637 /UG=Hs.132463 phosphoinositide-3-kinase, class 2, beta polypeptide /FL=gb:NM_002646.1 NM_002646 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta PIK3C2B 5287 NM_002646 /// XM_005245257 /// XM_005245258 /// XM_006711384 /// XR_241085 /// XR_241086 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // not recorded /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0001727 // lipid kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // non-traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 204485_s_at NM_005486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005486.1 /DEF=Homo sapiens target of myb1 (chicken) homolog-like 1 (TOM1L1), mRNA. /FEA=mRNA /GEN=TOM1L1 /PROD=target of myb1 (chicken) homolog-like 1 /DB_XREF=gi:4885638 /UG=Hs.153504 target of myb1 (chicken) homolog-like 1 /FL=gb:NM_005486.1 NM_005486 target of myb1 (chicken)-like 1 TOM1L1 10040 NM_005486 /// XM_005256914 /// XM_005256915 /// XM_006721630 /// XR_243612 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // non-traceable author statement /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 2000278 // regulation of DNA biosynthetic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // traceable author statement 204486_at U89364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U89364.1 /DEF=Homo sapiens voltage gated potassium channel (KVLQT1) mRNA, complete cds. /FEA=mRNA /GEN=KVLQT1 /PROD=voltage gated potassium channel /DB_XREF=gi:2465514 /UG=Hs.156115 potassium voltage-gated channel, KQT-like subfamily, member 1 /FL=gb:U89364.1 gb:NM_000218.1 U89364 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding) /// uncharacterized LOC101927338 KCNQ1OT1 /// LOC101927338 10984 /// 101927338 NR_002728 /// XR_241565 /// XR_249544 /// XR_251446 204487_s_at NM_000218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000218.1 /DEF=Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1), mRNA. /FEA=mRNA /GEN=KCNQ1 /PROD=potassium voltage-gated channel, KQT-likesubfamily precursor, member 1 /DB_XREF=gi:4557688 /UG=Hs.156115 potassium voltage-gated channel, KQT-like subfamily, member 1 /FL=gb:U89364.1 gb:NM_000218.1 NM_000218 potassium voltage-gated channel, KQT-like subfamily, member 1 KCNQ1 3784 NM_000218 /// NM_181797 /// NM_181798 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008016 // regulation of heart contraction // inferred by curator /// 0008584 // male gonad development // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060306 // regulation of membrane repolarization // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060454 // positive regulation of gastric acid secretion // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // traceable author statement /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0008157 // protein phosphatase 1 binding // inferred from direct assay /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0086089 // voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0097110 // scaffold protein binding // inferred from physical interaction /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 204488_at NM_014908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014908.1 /DEF=Homo sapiens KIAA1094 protein (KIAA1094), mRNA. /FEA=mRNA /GEN=KIAA1094 /PROD=KIAA1094 protein /DB_XREF=gi:7662481 /UG=Hs.161166 KIAA1094 protein /FL=gb:AB029017.1 gb:NM_014908.1 NM_014908 dolichol kinase DOLK 22845 NM_014908 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043048 // dolichyl monophosphate biosynthetic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004168 // dolichol kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204489_s_at NM_000610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000610.1 /DEF=Homo sapiens CD44 antigen (homing function and Indian blood group system) (CD44), mRNA. /FEA=mRNA /GEN=CD44 /PROD=CD44 antigen (homing function and Indian bloodgroup system) /DB_XREF=gi:10835162 /UG=Hs.169610 CD44 antigen (homing function and Indian blood group system) /FL=gb:NM_000610.1 gb:U40373.1 gb:M59040.1 gb:M24915.1 NM_000610 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 204490_s_at M24915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24915.1 /DEF=Human CDw44 antigen, complete cds. /FEA=mRNA /DB_XREF=gi:180196 /UG=Hs.169610 CD44 antigen (homing function and Indian blood group system) /FL=gb:NM_000610.1 gb:U40373.1 gb:M59040.1 gb:M24915.1 M24915 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 204491_at R40917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R40917 /FEA=EST /DB_XREF=gi:823119 /DB_XREF=est:yf75d09.s1 /CLONE=IMAGE:28220 /UG=Hs.172081 phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) /FL=gb:L20969.1 gb:U02882.1 gb:NM_006203.1 R40917 phosphodiesterase 4D, cAMP-specific PDE4D 5144 NM_001104631 /// NM_001165899 /// NM_001197218 /// NM_001197219 /// NM_001197220 /// NM_001197221 /// NM_001197222 /// NM_001197223 /// NM_006203 /// XM_005248537 /// XM_005248538 /// XM_005248540 /// XM_005248541 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0032754 // positive regulation of interleukin-5 production // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 0086024 // adrenergic receptor signaling pathway involved in positive regulation of heart rate // inferred by curator /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0030552 // cAMP binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 204492_at NM_014783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014783.1 /DEF=Homo sapiens KIAA0013 gene product (KIAA0013), mRNA. /FEA=mRNA /GEN=KIAA0013 /PROD=KIAA0013 gene product /DB_XREF=gi:7661857 /UG=Hs.172652 KIAA0013 gene product /FL=gb:D87717.1 gb:NM_014783.1 NM_014783 Rho GTPase activating protein 11A ARHGAP11A 9824 NM_001286479 /// NM_001286480 /// NM_014783 /// NM_199357 /// XM_005254808 /// XM_006720788 /// XM_006725564 /// XM_006725565 /// XR_429508 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 204493_at NM_001196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001196.1 /DEF=Homo sapiens BH3 interacting domain death agonist (BID), mRNA. /FEA=mRNA /GEN=BID /PROD=BH3 interacting domain death agonist /DB_XREF=gi:4557360 /UG=Hs.172894 BH3 interacting domain death agonist /FL=gb:AF042083.1 gb:NM_001196.1 NM_001196 BH3 interacting domain death agonist BID 637 NM_001196 /// NM_001244567 /// NM_001244569 /// NM_001244570 /// NM_001244572 /// NM_197966 /// NM_197967 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0090150 // establishment of protein localization to membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 204494_s_at AW516789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW516789 /FEA=EST /DB_XREF=gi:7154955 /DB_XREF=est:xq04c06.x1 /CLONE=IMAGE:2748874 /UG=Hs.17936 DKFZP434H132 protein /FL=gb:BC000540.1 gb:NM_015492.1 AW516789 chromosome 15 open reading frame 39 C15orf39 56905 NM_015492 /// XM_005254551 /// XM_006720613 0005737 // cytoplasm // inferred from direct assay 204495_s_at NM_015492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015492.1 /DEF=Homo sapiens DKFZP434H132 protein (DKFZP434H132), mRNA. /FEA=mRNA /GEN=DKFZP434H132 /PROD=DKFZP434H132 protein /DB_XREF=gi:7661575 /UG=Hs.17936 DKFZP434H132 protein /FL=gb:BC000540.1 gb:NM_015492.1 NM_015492 chromosome 15 open reading frame 39 C15orf39 56905 NM_015492 /// XM_005254551 /// XM_006720613 0005737 // cytoplasm // inferred from direct assay 204496_at NM_014574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014574.1 /DEF=Homo sapiens nuclear autoantigen (GS2NA), mRNA. /FEA=mRNA /GEN=GS2NA /PROD=nuclear autoantigen /DB_XREF=gi:11128016 /UG=Hs.183105 nuclear autoantigen /FL=gb:NM_014574.1 gb:U17989.1 NM_014574 striatin, calmodulin binding protein 3 STRN3 29966 NM_001083893 /// NM_014574 /// XM_005267569 /// XM_005267570 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0032355 // response to estradiol // inferred from sequence or structural similarity /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 204497_at AB011092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011092.1 /DEF=Homo sapiens mRNA for KIAA0520 protein, partial cds. /FEA=mRNA /GEN=KIAA0520 /PROD=KIAA0520 protein /DB_XREF=gi:3043563 /UG=Hs.20196 adenylate cyclase 9 /FL=gb:AF036927.1 gb:NM_001116.1 AB011092 adenylate cyclase 9 ADCY9 115 NM_001116 /// XM_005255079 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204498_s_at NM_001116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001116.1 /DEF=Homo sapiens adenylate cyclase 9 (ADCY9), mRNA. /FEA=mRNA /GEN=ADCY9 /PROD=adenylate cyclase 9 /DB_XREF=gi:4557258 /UG=Hs.20196 adenylate cyclase 9 /FL=gb:AF036927.1 gb:NM_001116.1 NM_001116 adenylate cyclase 9 ADCY9 115 NM_001116 /// XM_005255079 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204499_at AB028958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028958.1 /DEF=Homo sapiens mRNA for KIAA1035 protein, partial cds. /FEA=mRNA /GEN=KIAA1035 /PROD=KIAA1035 protein /DB_XREF=gi:5689406 /UG=Hs.21542 KIAA1035 protein /FL=gb:NM_015239.1 AB028958 ATP/GTP binding protein 1 AGTPBP1 23287 NM_001286715 /// NM_001286717 /// NM_015239 /// XM_005251847 /// XM_005251848 /// XM_005251849 0001754 // eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0021772 // olfactory bulb development // inferred from sequence or structural similarity /// 0035609 // C-terminal protein deglutamylation // inferred from sequence or structural similarity /// 0035610 // protein side chain deglutamylation // inferred from sequence or structural similarity /// 0042133 // neurotransmitter metabolic process // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204500_s_at NM_015239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015239.1 /DEF=Homo sapiens KIAA1035 protein (KIAA1035), mRNA. /FEA=mRNA /GEN=KIAA1035 /PROD=KIAA1035 protein /DB_XREF=gi:7662451 /UG=Hs.21542 KIAA1035 protein /FL=gb:NM_015239.1 NM_015239 ATP/GTP binding protein 1 AGTPBP1 23287 NM_001286715 /// NM_001286717 /// NM_015239 /// XM_005251847 /// XM_005251848 /// XM_005251849 0001754 // eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0021772 // olfactory bulb development // inferred from sequence or structural similarity /// 0035609 // C-terminal protein deglutamylation // inferred from sequence or structural similarity /// 0035610 // protein side chain deglutamylation // inferred from sequence or structural similarity /// 0042133 // neurotransmitter metabolic process // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204501_at NM_002514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002514.1 /DEF=Homo sapiens nephroblastoma overexpressed gene (NOV), mRNA. /FEA=mRNA /GEN=NOV /PROD=nephroblastoma overexpressed gene /DB_XREF=gi:4505422 /UG=Hs.235935 nephroblastoma overexpressed gene /FL=gb:NM_002514.1 NM_002514 nephroblastoma overexpressed NOV 4856 NM_002514 0001558 // regulation of cell growth // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 204502_at NM_015474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015474.1 /DEF=Homo sapiens DKFZP564A032 protein (DKFZP564A032), mRNA. /FEA=mRNA /GEN=DKFZP564A032 /PROD=DKFZP564A032 protein /DB_XREF=gi:7661593 /UG=Hs.23889 DKFZP564A032 protein /FL=gb:AB013847.1 gb:AL050267.1 gb:AF228421.1 gb:NM_015474.1 NM_015474 SAM domain and HD domain 1 SAMHD1 25939 NM_015474 /// XM_005260384 0002376 // immune system process // inferred from electronic annotation /// 0006203 // dGTP catabolic process // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from mutant phenotype /// 0046061 // dATP catabolic process // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008832 // dGTPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032567 // dGTP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204503_at NM_001988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001988.1 /DEF=Homo sapiens envoplakin (EVPL), mRNA. /FEA=mRNA /GEN=EVPL /PROD=envoplakin /DB_XREF=gi:4503612 /UG=Hs.25482 envoplakin /FL=gb:U53786.1 gb:NM_001988.1 NM_001988 envoplakin EVPL 2125 NM_001988 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay 204504_s_at NM_003609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003609.1 /DEF=Homo sapiens HIRA-interacting protein 3 (HIRIP3), mRNA. /FEA=mRNA /GEN=HIRIP3 /PROD=HIRA-interacting protein 3 /DB_XREF=gi:5803030 /UG=Hs.26484 HIRA-interacting protein 3 /FL=gb:BC000588.1 gb:NM_003609.1 NM_003609 HIRA interacting protein 3 HIRIP3 8479 NM_001197323 /// NM_003609 0006333 // chromatin assembly or disassembly // traceable author statement 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204505_s_at NM_001978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001978.1 /DEF=Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), mRNA. /FEA=mRNA /GEN=EPB49 /PROD=erythrocyte membrane protein band 4.9 (dematin) /DB_XREF=gi:4503580 /UG=Hs.274122 erythrocyte membrane protein band 4.9 (dematin) /FL=gb:NM_001978.1 gb:U28389.1 NM_001978 dematin actin binding protein DMTN 2039 NM_001114135 /// NM_001114136 /// NM_001114137 /// NM_001114138 /// NM_001114139 /// NM_001978 /// XM_005273431 /// XM_005273432 /// XM_005273433 /// XM_005273434 /// XM_005273435 /// XM_005273436 /// XM_005273438 /// XM_005273439 /// XM_005273440 /// XM_005273441 /// XM_005273442 /// XM_005273443 /// XM_005273444 /// XM_005273445 /// XM_005273446 /// XM_006716300 /// XM_006716301 0006461 // protein complex assembly // inferred from direct assay /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010591 // regulation of lamellipodium assembly // inferred from mutant phenotype /// 0010763 // positive regulation of fibroblast migration // inferred from sequence or structural similarity /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030194 // positive regulation of blood coagulation // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from sequence or structural similarity /// 0035585 // calcium-mediated signaling using extracellular calcium source // inferred from sequence or structural similarity /// 0048821 // erythrocyte development // inferred from sequence or structural similarity /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0051017 // actin filament bundle assembly // traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0070560 // protein secretion by platelet // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090527 // actin filament reorganization // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1901731 // positive regulation of platelet aggregation // inferred from sequence or structural similarity /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from direct assay /// 0031253 // cell projection membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay 204506_at AL544951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL544951 /FEA=EST /DB_XREF=gi:12877432 /DB_XREF=est:AL544951 /CLONE=CS0DI012YC11 (5 prime) /UG=Hs.278540 protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I) /FL=gb:M30773.1 gb:NM_000945.1 AL544951 protein phosphatase 3, regulatory subunit B, alpha PPP3R1 5534 NM_000945 0006915 // apoptotic process // traceable author statement /// 0016311 // dephosphorylation // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004723 // calcium-dependent protein serine/threonine phosphatase activity // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204507_s_at NM_000945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000945.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I) (PPP3R1), mRNA. /FEA=mRNA /GEN=PPP3R1 /PROD=protein phosphatase 3 (formerly 2B), regulatorysubunit B (19kD), alpha isoform (calcineurin B, type I) /DB_XREF=gi:4506024 /UG=Hs.278540 protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I) /FL=gb:M30773.1 gb:NM_000945.1 NM_000945 protein phosphatase 3, regulatory subunit B, alpha PPP3R1 5534 NM_000945 0006915 // apoptotic process // traceable author statement /// 0016311 // dephosphorylation // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004723 // calcium-dependent protein serine/threonine phosphatase activity // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204508_s_at BC001012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001012.1 /DEF=Homo sapiens, hypothetical protein FLJ20151, clone MGC:1073, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20151 /DB_XREF=gi:12654376 /UG=Hs.279916 hypothetical protein FLJ20151 /FL=gb:BC001012.1 gb:NM_017689.1 BC001012 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032438 // melanosome organization // inferred by curator /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204509_at NM_017689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017689.1 /DEF=Homo sapiens hypothetical protein FLJ20151 (FLJ20151), mRNA. /FEA=mRNA /GEN=FLJ20151 /PROD=hypothetical protein FLJ20151 /DB_XREF=gi:8923149 /UG=Hs.279916 hypothetical protein FLJ20151 /FL=gb:BC001012.1 gb:NM_017689.1 NM_017689 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204510_at NM_003503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003503.2 /DEF=Homo sapiens CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1 (CDC7L1), mRNA. /FEA=mRNA /GEN=CDC7L1 /PROD=CDC7-like 1 /DB_XREF=gi:11038647 /UG=Hs.28853 CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1 /FL=gb:NM_003503.2 gb:AB003698.1 gb:AF005209.1 gb:AF015592.1 NM_003503 cell division cycle 7 CDC7 8317 NM_001134419 /// NM_001134420 /// NM_003503 /// XM_005271241 /// XM_005271244 /// XM_005271245 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204511_at NM_014808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014808.1 /DEF=Homo sapiens KIAA0793 gene product (KIAA0793), mRNA. /FEA=mRNA /GEN=KIAA0793 /PROD=KIAA0793 gene product /DB_XREF=gi:7662309 /UG=Hs.301283 KIAA0793 gene product /FL=gb:AB018336.1 gb:NM_014808.1 NM_014808 FERM, RhoGEF and pleckstrin domain protein 2 FARP2 9855 NM_001282983 /// NM_001282984 /// NM_014808 /// XM_005247049 /// XM_005247050 /// XR_427126 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0016322 // neuron remodeling // inferred from direct assay /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033623 // regulation of integrin activation // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 0071800 // podosome assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity 204512_at NM_002114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002114.1 /DEF=Homo sapiens human immunodeficiency virus type I enhancer-binding protein 1 (HIVEP1), mRNA. /FEA=mRNA /GEN=HIVEP1 /PROD=human immunodeficiency virus type Ienhancer-binding protein 1 /DB_XREF=gi:4504388 /UG=Hs.306 human immunodeficiency virus type I enhancer-binding protein 1 /FL=gb:M32019.1 gb:NM_002114.1 NM_002114 human immunodeficiency virus type I enhancer binding protein 1 HIVEP1 3096 NM_002114 /// XM_005249042 /// XR_241895 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204513_s_at NM_014800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014800.1 /DEF=Homo sapiens KIAA0281 gene product (KIAA0281), mRNA. /FEA=mRNA /GEN=KIAA0281 /PROD=KIAA0281 gene product /DB_XREF=gi:7662037 /UG=Hs.31463 KIAA0281 gene product /FL=gb:BC003051.1 gb:D87457.1 gb:NM_014800.1 NM_014800 engulfment and cell motility 1 ELMO1 9844 NM_001039459 /// NM_001206480 /// NM_001206482 /// NM_014800 /// NM_130442 /// NR_038120 /// XM_005249919 /// XM_005249920 /// XM_006715805 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from genetic interaction /// 0006915 // apoptotic process // non-traceable author statement /// 0006928 // cellular component movement // inferred from genetic interaction /// 0016032 // viral process // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from genetic interaction /// 0030029 // actin filament-based process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from genetic interaction /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction 204514_at NM_001384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001384.1 /DEF=Homo sapiens diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2 (DPH2L2), mRNA. /FEA=mRNA /GEN=DPH2L2 /PROD=diphthamide biosynthesis-like protein 2 /DB_XREF=gi:4557532 /UG=Hs.324830 diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2 /FL=gb:BC001389.1 gb:BC003181.1 gb:AF053003.1 gb:NM_001384.1 NM_001384 DPH2 homolog (S. cerevisiae) DPH2 1802 NM_001039589 /// NM_001384 /// NM_201399 /// XM_005270559 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204515_at NM_000862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000862.1 /DEF=Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), mRNA. /FEA=mRNA /GEN=HSD3B1 /PROD=hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 /DB_XREF=gi:4504506 /UG=Hs.38586 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 /FL=gb:M35493.1 gb:M27137.1 gb:NM_000862.1 NM_000862 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 HSD3B1 3283 NM_000862 0006694 // steroid biosynthetic process // inferred from sequence or structural similarity /// 0006702 // androgen biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // traceable author statement /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030868 // smooth endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from sequence or structural similarity /// 0004769 // steroid delta-isomerase activity // inferred from sequence or structural similarity /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 204516_at BG390306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG390306 /FEA=EST /DB_XREF=gi:13283754 /DB_XREF=est:602416274F1 /CLONE=IMAGE:4524618 /UG=Hs.108447 spinocerebellar ataxia 7 (olivopontocerebellar atrophy with retinal degeneration) /FL=gb:NM_000333.1 BG390306 ataxin 7 ATXN7 6314 NM_000333 /// NM_001128149 /// NM_001177387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006997 // nucleus organization // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204517_at BE962749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962749 /FEA=EST /DB_XREF=gi:11765968 /DB_XREF=est:601656143R1 /CLONE=IMAGE:3855754 /UG=Hs.110364 peptidylprolyl isomerase C (cyclophilin C) /FL=gb:BC002678.1 gb:NM_000943.1 BE962749 peptidylprolyl isomerase C (cyclophilin C) PPIC 5480 NM_000943 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 204518_s_at NM_000943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000943.1 /DEF=Homo sapiens peptidylprolyl isomerase C (cyclophilin C) (PPIC), mRNA. /FEA=mRNA /GEN=PPIC /PROD=peptidylprolyl isomerase C (cyclophilin C) /DB_XREF=gi:4505990 /UG=Hs.110364 peptidylprolyl isomerase C (cyclophilin C) /FL=gb:BC002678.1 gb:NM_000943.1 NM_000943 peptidylprolyl isomerase C (cyclophilin C) PPIC 5480 NM_000943 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 204519_s_at NM_015993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015993.1 /DEF=Homo sapiens plasmolipin (LOC51090), mRNA. /FEA=mRNA /GEN=LOC51090 /PROD=plasmolipin /DB_XREF=gi:7705754 /UG=Hs.12701 plasmolipin /FL=gb:AF137386.1 gb:NM_015993.1 NM_015993 plasmolipin PLLP 51090 NM_015993 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 204520_x_at NM_014577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014577.1 /DEF=Homo sapiens bromodomain-containing 1 (BRD1), mRNA. /FEA=mRNA /GEN=BRD1 /PROD=bromodomain-containing protein 1 /DB_XREF=gi:11321641 /UG=Hs.127950 bromodomain-containing 1 /FL=gb:NM_014577.1 gb:AF005067.1 NM_014577 bromodomain containing 1 BRD1 23774 NM_014577 /// XM_005261470 /// XM_005261471 /// XM_005261472 /// XM_005261473 /// XM_006724210 /// XM_006724211 /// XM_006724212 /// XM_006724213 /// XM_006724214 /// XM_006724215 /// XM_006724216 /// XR_244359 /// XR_244360 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204521_at NM_013300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013300.1 /DEF=Homo sapiens protein predicted by clone 23733 (HSU79274), mRNA. /FEA=mRNA /GEN=HSU79274 /PROD=protein predicted by clone 23733 /DB_XREF=gi:9558740 /UG=Hs.150555 protein predicted by clone 23733 /FL=gb:U79274.1 gb:NM_013300.1 NM_013300 family with sequence similarity 216, member A FAM216A 29902 NM_013300 /// XM_005253875 204522_at NM_005510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005510.1 /DEF=Homo sapiens DOM-3 (C. elegans) homolog Z (DOM3Z), mRNA. /FEA=mRNA /GEN=DOM3Z /PROD=DOM-3 (C. elegans) homolog Z /DB_XREF=gi:5031670 /UG=Hs.153299 DOM-3 (C. elegans) homolog Z /FL=gb:AF059252.1 gb:NM_005510.1 NM_005510 decapping exoribonuclease DXO 1797 NM_005510 /// XM_006715005 /// XM_006715006 /// XM_006715007 /// XM_006725474 /// XM_006725475 /// XM_006725476 /// XM_006725688 /// XM_006725689 /// XM_006725690 /// XM_006725898 /// XM_006725899 /// XM_006725900 /// XM_006725985 /// XM_006725986 /// XM_006725987 /// XM_006726078 /// XM_006726079 /// XM_006726080 /// XR_427826 /// XR_430856 /// XR_430934 /// XR_430935 /// XR_430996 /// XR_431013 /// XR_431043 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0050779 // RNA destabilization // inferred from sequence or structural similarity /// 0071028 // nuclear mRNA surveillance // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008409 // 5'-3' exonuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034353 // RNA pyrophosphohydrolase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 204523_at NM_003440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003440.1 /DEF=Homo sapiens zinc finger protein 140 (clone pHZ-39) (ZNF140), mRNA. /FEA=mRNA /GEN=ZNF140 /PROD=zinc finger protein 140 (clone pHZ-39) /DB_XREF=gi:4507990 /UG=Hs.154205 zinc finger protein 140 (clone pHZ-39) /FL=gb:NM_003440.1 NM_003440 zinc finger protein 140 ZNF140 7699 NM_003440 /// XM_005266188 /// XM_005266190 /// XR_245353 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 204524_at NM_002613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002613.1 /DEF=Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), mRNA. /FEA=mRNA /GEN=PDPK1 /PROD=3-phosphoinositide dependent protein kinase-1 /DB_XREF=gi:4505694 /UG=Hs.154729 3-phosphoinositide dependent protein kinase-1 /FL=gb:AF017995.1 gb:NM_002613.1 NM_002613 3-phosphoinositide-dependent protein kinase 1-like /// 3-phosphoinositide dependent protein kinase 1 LOC101060747 /// PDPK1 5170 /// 101060747 NM_001261816 /// NM_002613 /// NM_031268 /// XM_003960883 /// XM_005255356 /// XM_005275768 /// XM_006709997 /// XM_006709998 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0010594 // regulation of endothelial cell migration // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043304 // regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004676 // 3-phosphoinositide-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from mutant phenotype /// 0016301 // kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 204525_at NM_014660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014660.1 /DEF=Homo sapiens KIAA0783 gene product (KIAA0783), mRNA. /FEA=mRNA /GEN=KIAA0783 /PROD=KIAA0783 gene product /DB_XREF=gi:7662303 /UG=Hs.156276 KIAA0783 gene product /FL=gb:AB018326.1 gb:NM_014660.1 NM_014660 PHD finger protein 14 PHF14 9678 NM_001007157 /// NM_014660 /// NR_033435 /// NR_033436 /// XM_005249908 /// XM_005249909 /// XM_005249910 /// XM_005249911 /// XM_006715801 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204526_s_at NM_007063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007063.1 /DEF=Homo sapiens vascular Rab-GAPTBC-containing (VRP), mRNA. /FEA=mRNA /GEN=VRP /PROD=vascular Rab-GAPTBC-containing /DB_XREF=gi:5902153 /UG=Hs.164170 vascular Rab-GAPTBC-containing /FL=gb:AB024057.1 gb:NM_007063.1 NM_007063 TBC1 domain family, member 8 (with GRAM domain) TBC1D8 11138 NM_001102426 /// NM_007063 /// XM_005263862 /// XM_005263863 /// XM_005263864 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 204527_at NM_000259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000259.1 /DEF=Homo sapiens myosin VA (heavy polypeptide 12, myoxin) (MYO5A), mRNA. /FEA=mRNA /GEN=MYO5A /PROD=myosin VA (heavy polypeptide 12, myoxin) /DB_XREF=gi:10835118 /UG=Hs.170157 myosin VA (heavy polypeptide 12, myoxin) /FL=gb:NM_000259.1 gb:U90942.1 NM_000259 myosin VA (heavy chain 12, myoxin) MYO5A 4644 NM_000259 /// NM_001142495 /// XM_005254397 /// XM_005254398 /// XM_005254399 /// XM_005254400 /// XM_005254401 /// XM_005254402 /// XM_005254403 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0031987 // locomotion involved in locomotory behavior // inferred from electronic annotation /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051643 // endoplasmic reticulum localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030426 // growth cone // non-traceable author statement /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation 204528_s_at NM_004537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004537.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 1 (NAP1L1), mRNA. /FEA=mRNA /GEN=NAP1L1 /PROD=nucleosome assembly protein 1-like 1 /DB_XREF=gi:4758755 /UG=Hs.179662 nucleosome assembly protein 1-like 1 /FL=gb:M86667.1 gb:NM_004537.1 NM_004537 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204529_s_at AI961231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI961231 /FEA=EST /DB_XREF=gi:5753944 /DB_XREF=est:wt15c09.x1 /CLONE=IMAGE:2507536 /UG=Hs.184297 KIAA0808 gene product /FL=gb:AB018351.1 gb:NM_014729.1 AI961231 thymocyte selection-associated high mobility group box TOX 9760 NM_014729 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 204530_s_at NM_014729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014729.1 /DEF=Homo sapiens KIAA0808 gene product (KIAA0808), mRNA. /FEA=mRNA /GEN=KIAA0808 /PROD=KIAA0808 gene product /DB_XREF=gi:7662321 /UG=Hs.184297 KIAA0808 gene product /FL=gb:AB018351.1 gb:NM_014729.1 NM_014729 thymocyte selection-associated high mobility group box TOX 9760 NM_014729 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 204531_s_at NM_007295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007295.1 /DEF=Homo sapiens breast cancer 1, early onset (BRCA1), transcript variant BRCA1b, mRNA. /FEA=mRNA /GEN=BRCA1 /PROD=breast cancer 1, early onset /DB_XREF=gi:6552300 /UG=Hs.194143 breast cancer 1, early onset /FL=gb:NM_007295.1 NM_007295 breast cancer 1, early onset BRCA1 672 NM_007294 /// NM_007295 /// NM_007296 /// NM_007297 /// NM_007298 /// NM_007299 /// NM_007300 /// NM_007301 /// NM_007302 /// NM_007303 /// NM_007305 /// NM_007306 /// NR_027676 /// XM_006722029 /// XM_006722030 /// XM_006722031 /// XM_006722032 /// XM_006722033 /// XM_006722034 /// XM_006722035 /// XM_006722036 /// XM_006722037 /// XM_006722038 /// XM_006722039 /// XM_006722040 /// XM_006722041 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043009 // chordate embryonic development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0044030 // regulation of DNA methylation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046600 // negative regulation of centriole replication // non-traceable author statement /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from direct assay /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070512 // positive regulation of histone H4-K20 methylation // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay /// 2000145 // regulation of cell motility // inferred from direct assay /// 2000617 // positive regulation of histone H3-K9 acetylation // inferred from direct assay /// 2000620 // positive regulation of histone H4-K16 acetylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008274 // gamma-tubulin ring complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031436 // BRCA1-BARD1 complex // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015631 // tubulin binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 204532_x_at NM_021027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021027.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A9 (UGT1A9), mRNA. /FEA=mRNA /GEN=UGT1A9 /PROD=UDP glycosyltransferase 1 family, polypeptideA9 /DB_XREF=gi:11276084 /UG=Hs.2056 UDP glycosyltransferase 1 family, polypeptide A9 /FL=gb:NM_021027.1 gb:U89507.1 gb:U89508.1 gb:S55985.1 gb:AF030310.1 gb:AF056188.1 NM_021027 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A10 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A10 /// UGT1A4 /// UGT1A6 /// UGT1A8 /// UGT1A9 54575 /// 54576 /// 54578 /// 54600 /// 54657 /// 54658 NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_021027 /// NM_205862 0001889 // liver development // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0001972 // retinoic acid binding // inferred by curator /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 204533_at NM_001565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001565.1 /DEF=Homo sapiens small inducible cytokine subfamily B (Cys-X-Cys), member 10 (SCYB10), mRNA. /FEA=mRNA /GEN=SCYB10 /PROD=interferon gamma-induced precursor /DB_XREF=gi:4504700 /UG=Hs.2248 small inducible cytokine subfamily B (Cys-X-Cys), member 10 /FL=gb:NM_001565.1 NM_001565 chemokine (C-X-C motif) ligand 10 CXCL10 3627 NM_001565 0002690 // positive regulation of leukocyte chemotaxis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007267 // cell-cell signaling // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009306 // protein secretion // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010818 // T cell chemotaxis // inferred from mutant phenotype /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045859 // regulation of protein kinase activity // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 204534_at NM_000638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000638.1 /DEF=Homo sapiens vitronectin (serum spreading factor, somatomedin B, complement S-protein) (VTN), mRNA. /FEA=mRNA /GEN=VTN /PROD=vitronectin (serum spreading factor, somatomedinB, complement S-protein) /DB_XREF=gi:10835190 /UG=Hs.2257 vitronectin (serum spreading factor, somatomedin B, complement S-protein) /FL=gb:NM_000638.1 gb:BC005046.1 NM_000638 SEBOX homeobox /// vitronectin SEBOX /// VTN 7448 /// 645832 NM_000638 /// NM_001080837 /// NM_001083896 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0033627 // cell adhesion mediated by integrin // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0061302 // smooth muscle cell-matrix adhesion // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred by curator 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 204535_s_at AI978576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI978576 /FEA=EST /DB_XREF=gi:5803606 /DB_XREF=est:wq72c11.x1 /CLONE=IMAGE:2476820 /UG=Hs.227630 RE1-silencing transcription factor /FL=gb:U22680.1 gb:U22314.1 gb:NM_005612.1 AI978576 RE1-silencing transcription factor REST 5978 NM_001193508 /// NM_005612 /// XM_005265760 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045665 // negative regulation of neuron differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from sequence or structural similarity /// 0070933 // histone H4 deacetylation // inferred from direct assay /// 0071257 // cellular response to electrical stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from mutant phenotype /// 2000706 // negative regulation of dense core granule biogenesis // inferred from sequence or structural similarity /// 2000740 // negative regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype /// 2000798 // negative regulation of amniotic stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204536_s_at NM_005612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005612.1 /DEF=Homo sapiens RE1-silencing transcription factor (REST), mRNA. /FEA=mRNA /GEN=REST /PROD=RE1-silencing transcription factor /DB_XREF=gi:5032036 /UG=Hs.227630 RE1-silencing transcription factor /FL=gb:U22680.1 gb:U22314.1 gb:NM_005612.1 NM_005612 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from electronic annotation /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from sequence or structural similarity /// 0070933 // histone H4 deacetylation // inferred from direct assay /// 0071257 // cellular response to electrical stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from mutant phenotype /// 2000706 // negative regulation of dense core granule biogenesis // inferred from sequence or structural similarity /// 2000740 // negative regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype /// 2000798 // negative regulation of amniotic stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204537_s_at NM_004961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004961.2 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, epsilon (GABRE), transcript variant 1, mRNA. /FEA=mRNA /GEN=GABRE /PROD=gamma-aminobutyric acid (GABA) A receptor,epsilon, isoform 1 precursor /DB_XREF=gi:12707559 /UG=Hs.22785 gamma-aminobutyric acid (GABA) A receptor, epsilon /FL=gb:NM_004961.2 gb:U66661.1 NM_004961 gamma-aminobutyric acid (GABA) A receptor, epsilon /// microRNA 224 /// microRNA 452 GABRE /// MIR224 /// MIR452 2564 /// 407009 /// 574412 NM_004961 /// NM_021984 /// NM_021987 /// NM_021990 /// NR_029638 /// NR_029973 /// XM_006724812 /// XM_006724813 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 204538_x_at NM_006985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006985.1 /DEF=Homo sapiens nuclear pore complex interacting protein (NPIP), mRNA. /FEA=mRNA /GEN=NPIP /PROD=nuclear pore complex interacting protein /DB_XREF=gi:5902013 /UG=Hs.251928 nuclear pore complex interacting protein /FL=gb:AF132984.1 gb:NM_006985.1 NM_006985 nuclear pore complex interacting protein family, member A1 NPIPA1 9284 NM_006985 /// XM_005255694 /// XM_005255695 /// XM_006720979 /// XM_006720980 0006810 // transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 204539_s_at NM_014246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014246.1 /DEF=Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog (CELSR1), mRNA. /FEA=mRNA /GEN=CELSR1 /PROD=cadherin EGF LAG seven-pass G-type receptor 1 /DB_XREF=gi:7656966 /UG=Hs.252387 cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog /FL=gb:AF231024.1 gb:NM_014246.1 NM_014246 cadherin, EGF LAG seven-pass G-type receptor 1 CELSR1 9620 NM_014246 /// XM_006724383 0001736 // establishment of planar polarity // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042249 // establishment of planar polarity of embryonic epithelium // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0048105 // establishment of body hair planar orientation // inferred from electronic annotation /// 0060488 // orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060489 // planar dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060490 // lateral sprouting involved in lung morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090251 // protein localization involved in establishment of planar polarity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // non-traceable author statement 204540_at NM_001958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001958.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 alpha 2 (EEF1A2), mRNA. /FEA=mRNA /GEN=EEF1A2 /PROD=eukaryotic translation elongation factor 1 alpha2 /DB_XREF=gi:4503474 /UG=Hs.2642 eukaryotic translation elongation factor 1 alpha 2 /FL=gb:BC000432.1 gb:NM_001958.1 NM_001958 eukaryotic translation elongation factor 1 alpha 2 EEF1A2 1917 NM_001958 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // non-traceable author statement 204541_at NM_012429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012429.1 /DEF=Homo sapiens SEC14 (S. cerevisiae)-like 2 (SEC14L2), mRNA. /FEA=mRNA /GEN=SEC14L2 /PROD=SEC14 (S. cerevisiae)-like 2 /DB_XREF=gi:7110714 /UG=Hs.277728 SEC14 (S. cerevisiae)-like 2 /FL=gb:NM_012429.1 NM_012429 SEC14-like 2 (S. cerevisiae) SEC14L2 23541 NM_001204204 /// NM_001291932 /// NM_012429 /// NM_033382 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0045540 // regulation of cholesterol biosynthetic process // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005543 // phospholipid binding // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0008431 // vitamin E binding // non-traceable author statement 204542_at NM_006456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006456.1 /DEF=Homo sapiens sialyltransferase (STHM), mRNA. /FEA=mRNA /GEN=STHM /PROD=sialyltransferase /DB_XREF=gi:5454091 /UG=Hs.288215 sialyltransferase /FL=gb:NM_006456.1 gb:U14550.1 NM_006456 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 ST6GALNAC2 10610 NM_006456 /// XM_005256954 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 204543_at NM_005312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005312.1 /DEF=Homo sapiens guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene) (GRF2), mRNA. /FEA=mRNA /GEN=GRF2 /PROD=guanine nucleotide-releasing factor 2 /DB_XREF=gi:4885356 /UG=Hs.288675 guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene) /FL=gb:D21239.1 gb:NM_005312.1 NM_005312 Rap guanine nucleotide exchange factor (GEF) 1 RAPGEF1 2889 NM_005312 /// NM_198679 /// XM_005272185 /// XM_005272186 /// XM_005272191 /// XM_005272195 /// XM_006717067 /// XM_006717068 /// XM_006717069 /// XM_006717070 /// XM_006717071 /// XM_006717072 /// XM_006717073 /// XM_006717074 0000186 // activation of MAPKK activity // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0038180 // nerve growth factor signaling pathway // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0017124 // SH3 domain binding // inferred from electronic annotation 204544_at NM_007216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007216.1 /DEF=Homo sapiens alpha integrin binding protein 63 (KIAA1017), mRNA. /FEA=mRNA /GEN=KIAA1017 /PROD=alpha integrin binding protein 63 /DB_XREF=gi:6005795 /UG=Hs.29205 alpha integrin binding protein 63 /FL=gb:AB023234.1 gb:NM_007216.1 NM_007216 Hermansky-Pudlak syndrome 5 HPS5 11234 NM_007216 /// NM_181507 /// NM_181508 /// XM_005252761 /// XM_005252762 /// XM_005252763 /// XM_005252764 0006996 // organelle organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0031084 // BLOC-2 complex // inferred from physical interaction 0005515 // protein binding // inferred from electronic annotation 204545_at NM_000287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000287.1 /DEF=Homo sapiens peroxisomal biogenesis factor 6 (PEX6), mRNA. /FEA=mRNA /GEN=PEX6 /PROD=peroxisomal biogenesis factor 6 /DB_XREF=gi:4505728 /UG=Hs.301636 peroxisomal biogenesis factor 6 /FL=gb:D83703.1 gb:NM_000287.1 NM_000287 peroxisomal biogenesis factor 6 PEX6 5190 NM_000287 /// XM_005249180 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016561 // protein import into peroxisome matrix, translocation // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from mutant phenotype 204546_at NM_014732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014732.1 /DEF=Homo sapiens KIAA0513 gene product (KIAA0513), mRNA. /FEA=mRNA /GEN=KIAA0513 /PROD=KIAA0513 gene product /DB_XREF=gi:7662163 /UG=Hs.301658 KIAA0513 gene product /FL=gb:AB011085.1 gb:NM_014732.1 NM_014732 KIAA0513 KIAA0513 9764 NM_001286565 /// NM_001286566 /// NM_014732 /// XM_005256265 /// XM_005256267 0005737 // cytoplasm // inferred from electronic annotation 204547_at NM_006822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006822.1 /DEF=Homo sapiens GTP-binding protein homologous to Saccharomyces cerevisiae SEC4 (SEC4L), mRNA. /FEA=mRNA /GEN=SEC4L /PROD=GTP-binding protein homologous to Saccharomycescerevisiae SEC4 /DB_XREF=gi:5803162 /UG=Hs.302498 GTP-binding protein homologous to Saccharomyces cerevisiae SEC4 /FL=gb:U05227.1 gb:NM_006822.1 NM_006822 RAB40B, member RAS oncogene family RAB40B 10966 NM_006822 /// XM_005256334 /// XM_005256335 /// XM_006722271 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 204548_at NM_000349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000349.1 /DEF=Homo sapiens steroidogenic acute regulatory protein (STAR), mRNA. /FEA=mRNA /GEN=STAR /PROD=steroidogenic acute regulatory protein /DB_XREF=gi:4507250 /UG=Hs.3132 steroidogenic acute regulatory protein /FL=gb:AF035277.1 gb:NM_000349.1 gb:U17280.1 NM_000349 steroidogenic acute regulatory protein STAR 6770 NM_000349 /// NM_001007243 /// XM_005273619 /// XM_005273620 /// XM_006716392 /// XM_006716393 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0017143 // insecticide metabolic process // inferred from electronic annotation /// 0018879 // biphenyl metabolic process // inferred from electronic annotation /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0018958 // phenol-containing compound metabolic process // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042747 // circadian sleep/wake cycle, REM sleep // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044321 // response to leptin // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050756 // fractalkine metabolic process // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0061370 // testosterone biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071373 // cellular response to luteinizing hormone stimulus // inferred from electronic annotation /// 0071378 // cellular response to growth hormone stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from electronic annotation 204549_at NM_014002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014002.1 /DEF=Homo sapiens IKK-related kinase epsilon; inducible IkappaB kinase (IKKE), mRNA. /FEA=mRNA /GEN=IKKE /PROD=IKK-related kinase epsilon /DB_XREF=gi:7661945 /UG=Hs.321045 IKK-related kinase epsilon; inducible IkappaB kinase /FL=gb:D63485.1 gb:AB016590.1 gb:AF241789.1 gb:NM_014002.1 NM_014002 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon IKBKE 9641 NM_001193321 /// NM_001193322 /// NM_014002 /// XM_005273356 /// XM_006711641 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204550_x_at NM_000561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000561.1 /DEF=Homo sapiens glutathione S-transferase M1 (GSTM1), mRNA. /FEA=mRNA /GEN=GSTM1 /PROD=glutathione S-transferase M1 /DB_XREF=gi:10835126 /UG=Hs.324730 glutathione S-transferase M1 /FL=gb:NM_000561.1 gb:J03817.1 NM_000561 glutathione S-transferase mu 1 GSTM1 2944 NM_000561 /// NM_146421 /// XM_005270782 /// XM_005270783 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred by curator /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 204551_s_at NM_001622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001622.1 /DEF=Homo sapiens alpha-2-HS-glycoprotein (AHSG), mRNA. /FEA=mRNA /GEN=AHSG /PROD=alpha-2-HS-glycoprotein /DB_XREF=gi:4502004 /UG=Hs.324746 alpha-2-HS-glycoprotein /FL=gb:M16961.1 gb:NM_001622.1 NM_001622 alpha-2-HS-glycoprotein AHSG 197 NM_001622 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006907 // pinocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // non-traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype /// 0050766 // positive regulation of phagocytosis // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0019210 // kinase inhibitor activity // non-traceable author statement 204552_at AA355179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA355179 /FEA=EST /DB_XREF=gi:2007571 /DB_XREF=est:EST63624 /UG=Hs.32944 inositol polyphosphate-4-phosphatase, type I, 107kD /FL=gb:U26398.1 gb:NM_004027.1 AA355179 inositol polyphosphate-4-phosphatase, type I, 107kDa INPP4A 3631 NM_001134224 /// NM_001134225 /// NM_001566 /// NM_004027 /// XM_006712499 /// XM_006712500 /// XM_006712501 /// XM_006712502 /// XM_006712503 /// XM_006712504 /// XM_006712505 /// XM_006712506 /// XM_006712507 /// XM_006712508 /// XM_006712509 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016316 // phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034597 // phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity // inferred from electronic annotation 204553_x_at NM_004027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004027.1 /DEF=Homo sapiens inositol polyphosphate-4-phosphatase, type I, 107kD (INPP4A), transcript variant a, mRNA. /FEA=mRNA /GEN=INPP4A /PROD=inositol polyphosphate-4-phosphatase isoform a /DB_XREF=gi:4755139 /UG=Hs.32944 inositol polyphosphate-4-phosphatase, type I, 107kD /FL=gb:U26398.1 gb:NM_004027.1 NM_004027 inositol polyphosphate-4-phosphatase, type I, 107kDa INPP4A 3631 NM_001134224 /// NM_001134225 /// NM_001566 /// NM_004027 /// XM_006712499 /// XM_006712500 /// XM_006712501 /// XM_006712502 /// XM_006712503 /// XM_006712504 /// XM_006712505 /// XM_006712506 /// XM_006712507 /// XM_006712508 /// XM_006712509 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016316 // phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034597 // phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity // inferred from electronic annotation 204554_at AL109928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109928 /DEF=Human DNA sequence from clone RP4-551D2 on chromosome 20q13.2-13.33. Contains the gene for a novel Cadherin domain protein, a novel gene, the PPP1R6 gene for protein phosphatase 1 regulatory subunit 6, the 5 end of the SYCP2 gene for synaptonemal... /FEA=mRNA_6 /DB_XREF=gi:7981303 /UG=Hs.42215 protein phosphatase 1, regulatory subunit 6 /FL=gb:NM_006242.2 AL109928 protein phosphatase 1, regulatory subunit 3D PPP1R3D 5509 NM_006242 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement 0042587 // glycogen granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 204555_s_at NM_006242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006242.2 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 6 (PPP1R6), mRNA. /FEA=mRNA /GEN=PPP1R6 /PROD=protein phosphatase 1, regulatory subunit 6 /DB_XREF=gi:6806895 /UG=Hs.42215 protein phosphatase 1, regulatory subunit 6 /FL=gb:NM_006242.2 NM_006242 protein phosphatase 1, regulatory subunit 3D PPP1R3D 5509 NM_006242 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement 0042587 // glycogen granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 204556_s_at AL568422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568422 /FEA=EST /DB_XREF=gi:12922745 /DB_XREF=est:AL568422 /CLONE=CS0DE001YN18 (3 prime) /UG=Hs.60177 KIAA0996 protein /FL=gb:AB023213.1 gb:NM_014934.1 AL568422 DAZ interacting zinc finger protein 1 DZIP1 22873 NM_014934 /// NM_198968 /// XM_005254032 /// XM_006719916 /// XM_006719917 /// XM_006719918 /// XM_006719919 /// XM_006719920 /// XM_006719921 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // non-traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0043234 // protein complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204557_s_at NM_014934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014934.1 /DEF=Homo sapiens KIAA0996 protein (KIAA0996), mRNA. /FEA=mRNA /GEN=KIAA0996 /PROD=KIAA0996 protein /DB_XREF=gi:7662435 /UG=Hs.60177 KIAA0996 protein /FL=gb:AB023213.1 gb:NM_014934.1 NM_014934 DAZ interacting zinc finger protein 1 DZIP1 22873 NM_014934 /// NM_198968 /// XM_005254032 /// XM_006719916 /// XM_006719917 /// XM_006719918 /// XM_006719919 /// XM_006719920 /// XM_006719921 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // non-traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0043234 // protein complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204558_at NM_003579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003579.1 /DEF=Homo sapiens RAD54 (S.cerevisiae)-like (RAD54L), mRNA. /FEA=mRNA /GEN=RAD54L /PROD=RAD54 (S.cerevisiae)-like /DB_XREF=gi:4506396 /UG=Hs.66718 RAD54 (S.cerevisiae)-like /FL=gb:NM_003579.1 NM_003579 RAD54-like (S. cerevisiae) RAD54L 8438 NM_001142548 /// NM_003579 /// XM_006710975 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay 204559_s_at NM_016199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016199.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein LSm7 (LOC51690), mRNA. /FEA=mRNA /GEN=LOC51690 /PROD=U6 snRNA-associated Sm-like protein LSm7 /DB_XREF=gi:7706422 /UG=Hs.70830 U6 snRNA-associated Sm-like protein LSm7 /FL=gb:AF182293.1 gb:NM_016199.1 NM_016199 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM7 51690 NM_016199 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // non-traceable author statement 204560_at NM_004117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004117.1 /DEF=Homo sapiens FK506-binding protein 5 (FKBP5), mRNA. /FEA=mRNA /GEN=FKBP5 /PROD=FK506-binding protein 5 /DB_XREF=gi:4758383 /UG=Hs.7557 FK506-binding protein 5 /FL=gb:U71321.1 gb:NM_004117.1 NM_004117 FK506 binding protein 5 FKBP5 2289 NM_001145775 /// NM_001145776 /// NM_001145777 /// NM_004117 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from physical interaction 204561_x_at NM_000483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000483.2 /DEF=Homo sapiens apolipoprotein C-II (APOC2), mRNA. /FEA=mRNA /GEN=APOC2 /PROD=apolipoprotein C-II precursor /DB_XREF=gi:5174775 /UG=Hs.75615 apolipoprotein C-II /FL=gb:BC005348.1 gb:NM_000483.2 NM_000483 apolipoprotein C-II /// apolipoprotein C-IV /// APOC4-APOC2 readthrough (NMD candidate) APOC2 /// APOC4 /// APOC4-APOC2 344 /// 346 /// 100533990 NM_000483 /// NM_001646 /// NR_037932 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from direct assay /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0010902 // positive regulation of very-low-density lipoprotein particle remodeling // inferred by curator /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032375 // negative regulation of cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034370 // triglyceride-rich lipoprotein particle remodeling // traceable author statement /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred by curator /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred by curator /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from direct assay /// 0060697 // positive regulation of phospholipid catabolic process // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from mutant phenotype /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005319 // lipid transporter activity // traceable author statement /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0043274 // phospholipase binding // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060230 // lipoprotein lipase activator activity // inferred from direct assay 204562_at NM_002460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002460.1 /DEF=Homo sapiens interferon regulatory factor 4 (IRF4), mRNA. /FEA=mRNA /GEN=IRF4 /PROD=interferon regulatory factor 4 /DB_XREF=gi:4505286 /UG=Hs.82132 interferon regulatory factor 4 /FL=gb:U52682.1 gb:NM_002460.1 NM_002460 interferon regulatory factor 4 IRF4 3662 NM_001195286 /// NM_002460 /// NR_036585 /// NR_046000 /// XM_006715090 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0018022 // peptidyl-lysine methylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0042110 // T cell activation // non-traceable author statement /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045082 // positive regulation of interleukin-10 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045368 // positive regulation of interleukin-13 biosynthetic process // inferred from direct assay /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from direct assay /// 0045622 // regulation of T-helper cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0072540 // T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0016279 // protein-lysine N-methyltransferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 204563_at NM_000655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000655.2 /DEF=Homo sapiens selectin L (lymphocyte adhesion molecule 1) (SELL), mRNA. /FEA=mRNA /GEN=SELL /PROD=selectin L /DB_XREF=gi:5713320 /UG=Hs.82848 selectin L (lymphocyte adhesion molecule 1) /FL=gb:M25280.1 gb:NM_000655.2 NM_000655 selectin L SELL 6402 NM_000655 /// NR_029467 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0033198 // response to ATP // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 204564_at NM_006315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006315.1 /DEF=Homo sapiens ring finger protein 3 (RNF3), mRNA. /FEA=mRNA /GEN=RNF3 /PROD=ring finger protein 3 /DB_XREF=gi:5454011 /UG=Hs.8834 ring finger protein 3 /FL=gb:NM_006315.1 NM_006315 polycomb group ring finger 3 PCGF3 10336 NM_006315 /// XM_005272250 /// XM_005272252 /// XM_005272253 /// XM_005272254 /// XM_006713852 /// XM_006713853 /// XM_006713854 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204565_at NM_018473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018473.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT012 (HT012), mRNA. /FEA=mRNA /GEN=HT012 /PROD=uncharacterized hypothalamus protein HT012 /DB_XREF=gi:8923811 /UG=Hs.9676 uncharacterized hypothalamus protein HT012 /FL=gb:BC000894.1 gb:AF274952.1 gb:AF220186.1 gb:NM_018473.1 NM_018473 acyl-CoA thioesterase 13 ACOT13 55856 NM_001160094 /// NM_018473 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay 204566_at NM_003620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003620.1 /DEF=Homo sapiens protein phosphatase 1D magnesium-dependent, delta isoform (PPM1D), mRNA. /FEA=mRNA /GEN=PPM1D /PROD=protein phosphatase 1D magnesium-dependent,delta isoform /DB_XREF=gi:4505996 /UG=Hs.100980 protein phosphatase 1D magnesium-dependent, delta isoform /FL=gb:U78305.1 gb:NM_003620.1 NM_003620 protein phosphatase, Mg2+/Mn2+ dependent, 1D PPM1D 8493 NM_003620 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0006470 // protein dephosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009314 // response to radiation // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay 0005634 // nucleus // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204567_s_at NM_004915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004915.2 /DEF=Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCG1 /PROD=ATP-binding cassette sub-family G member 1isoform a /DB_XREF=gi:8051574 /UG=Hs.10237 ATP-binding cassette, sub-family G (WHITE), member 1 /FL=gb:NM_004915.2 NM_004915 ATP-binding cassette, sub-family G (WHITE), member 1 ABCG1 9619 NM_004915 /// NM_016818 /// NM_207174 /// NM_207627 /// NM_207628 /// NM_207629 /// NM_207630 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0009720 // detection of hormone stimulus // non-traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010872 // regulation of cholesterol esterification // inferred from sequence or structural similarity /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0010888 // negative regulation of lipid storage // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0033993 // response to lipid // inferred from direct assay /// 0034374 // low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034436 // glycoprotein transport // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042987 // amyloid precursor protein catabolic process // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055099 // response to high density lipoprotein particle // inferred from electronic annotation /// 1901998 // toxin transport // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // traceable author statement /// 0019534 // toxin transporter activity // inferred from direct assay /// 0034041 // sterol-transporting ATPase activity // inferred from direct assay /// 0034437 // glycoprotein transporter activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // non-traceable author statement 204568_at NM_014924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014924.1 /DEF=Homo sapiens KIAA0831 protein (KIAA0831), mRNA. /FEA=mRNA /GEN=KIAA0831 /PROD=KIAA0831 protein /DB_XREF=gi:7662325 /UG=Hs.103000 KIAA0831 protein /FL=gb:AB020638.1 gb:NM_014924.1 NM_014924 autophagy related 14 ATG14 22863 NM_014924 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204569_at NM_014920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014920.1 /DEF=Homo sapiens MAK-related kinase (KIAA0936), mRNA. /FEA=mRNA /GEN=KIAA0936 /PROD=KIAA0936 protein /DB_XREF=gi:7662387 /UG=Hs.108850 MAK-related kinase /FL=gb:AF152469.1 gb:AB023153.1 gb:AF225919.1 gb:NM_014920.1 gb:NM_016513.1 NM_014920 intestinal cell (MAK-like) kinase ICK 22858 NM_014920 /// NM_016513 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204570_at NM_001864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001864.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) (COX7A1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX7A1 /PROD=cytochrome c oxidase subunit VIIa polypeptide 1(muscle) /DB_XREF=gi:4502986 /UG=Hs.114346 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) /FL=gb:BC002757.1 gb:M83186.1 gb:NM_001864.1 NM_001864 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) COX7A1 1346 NM_001864 0006091 // generation of precursor metabolites and energy // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 204571_x_at BE797213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE797213 /FEA=EST /DB_XREF=gi:10218411 /DB_XREF=est:601587854F1 /CLONE=IMAGE:3942276 /UG=Hs.11774 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting, 4 (parvulin) /FL=gb:BC005234.1 gb:AF143096.1 gb:AB009690.1 gb:NM_006223.1 BE797213 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) PIN4 5303 NM_001170747 /// NM_006223 /// NR_033187 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030684 // preribosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003681 // bent DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204572_s_at NM_006223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006223.1 /DEF=Homo sapiens protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting, 4 (parvulin) (PIN4), mRNA. /FEA=mRNA /GEN=PIN4 /PROD=protein (peptidyl-prolyl cistrans isomerase)NIMA-interacting, 4 (parvulin) /DB_XREF=gi:5453901 /UG=Hs.11774 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting, 4 (parvulin) /FL=gb:BC005234.1 gb:AF143096.1 gb:AB009690.1 gb:NM_006223.1 NM_006223 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) PIN4 5303 NM_001170747 /// NM_006223 /// NR_033187 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030684 // preribosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003681 // bent DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204573_at NM_021151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021151.1 /DEF=Homo sapiens carnitine octanoyltransferase (COT), mRNA. /FEA=mRNA /GEN=COT /PROD=carnitine octanoyltransferase /DB_XREF=gi:10863952 /UG=Hs.12743 carnitine O-octanoyltransferase /FL=gb:NM_021151.1 gb:AF073770.1 gb:AF168793.1 NM_021151 carnitine O-octanoyltransferase CROT 54677 NM_001143935 /// NM_001243745 /// NM_021151 /// XM_006716031 0006091 // generation of precursor metabolites and energy // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from sequence or structural similarity /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // inferred from sequence or structural similarity /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051791 // medium-chain fatty acid metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005782 // peroxisomal matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0008458 // carnitine O-octanoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 204574_s_at NM_002429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002429.2 /DEF=Homo sapiens matrix metalloproteinase 19 (MMP19), transcript variant rasi-1, mRNA. /FEA=mRNA /GEN=MMP19 /PROD=matrix metalloproteinase 19, isoform rasi-1,preproprotein /DB_XREF=gi:13027788 /UG=Hs.154057 matrix metalloproteinase 19 /FL=gb:NM_002429.2 gb:U38321.1 gb:U37791.1 NM_002429 matrix metallopeptidase 19 MMP19 4327 NM_001032360 /// NM_001272101 /// NM_002429 /// NM_022790 /// NM_022792 /// NR_073606 /// XM_006719401 /// XR_429102 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001554 // luteolysis // inferred from electronic annotation /// 0006508 // proteolysis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204575_s_at U38321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38321.1 /DEF=Homo sapiens clone rasi-11 matrix metalloproteinase RASI-1 mRNA, complete cds. /FEA=mRNA /PROD=matrix metalloproteinase RASI-1 /DB_XREF=gi:2228243 /UG=Hs.154057 matrix metalloproteinase 19 /FL=gb:NM_002429.2 gb:U38321.1 gb:U37791.1 U38321 matrix metallopeptidase 19 MMP19 4327 NM_001032360 /// NM_001272101 /// NM_002429 /// NM_022790 /// NM_022792 /// NR_073606 /// XM_006719401 /// XR_429102 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001554 // luteolysis // inferred from electronic annotation /// 0006508 // proteolysis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204576_s_at AA207013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA207013 /FEA=EST /DB_XREF=gi:1802425 /DB_XREF=est:zr87c08.s1 /CLONE=IMAGE:682670 /UG=Hs.155995 KIAA0643 protein /FL=gb:NM_024793.1 AA207013 clusterin associated protein 1 CLUAP1 23059 NM_015041 /// NM_024793 /// XM_006720867 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204577_s_at NM_024793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024793.1 /DEF=Homo sapiens KIAA0643 protein (KIAA0643), mRNA. /FEA=mRNA /GEN=KIAA0643 /PROD=hypothetical protein FLJ13297 /DB_XREF=gi:13435144 /UG=Hs.155995 KIAA0643 protein /FL=gb:NM_024793.1 NM_024793 clusterin associated protein 1 CLUAP1 23059 NM_015041 /// NM_024793 /// XM_006720867 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204578_at NM_014659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014659.1 /DEF=Homo sapiens KIAA0377 gene product (KIAA0377), mRNA. /FEA=mRNA /GEN=KIAA0377 /PROD=KIAA0377 gene product /DB_XREF=gi:7662083 /UG=Hs.156814 KIAA0377 gene product /FL=gb:AB002375.1 gb:NM_014659.1 NM_014659 diphosphoinositol pentakisphosphate kinase 1 PPIP5K1 9677 NM_001024463 /// NM_001130858 /// NM_001130859 /// NM_001190214 /// NM_014659 /// XM_005254801 /// XM_005254802 /// XM_005254803 /// XM_005254804 /// XM_006720782 /// XM_006720783 /// XM_006720784 /// XM_006720785 /// XM_006720786 /// XM_006720787 0006020 // inositol metabolic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000827 // inositol-1,3,4,5,6-pentakisphosphate kinase activity // inferred from direct assay /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from direct assay /// 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033857 // diphosphoinositol-pentakisphosphate kinase activity // inferred from direct assay /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation 204579_at NM_002011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002011.2 /DEF=Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 1, mRNA. /FEA=mRNA /GEN=FGFR4 /PROD=fibroblast growth factor receptor 4, isoform 1precursor /DB_XREF=gi:13112051 /UG=Hs.165950 fibroblast growth factor receptor 4 /FL=gb:NM_002011.2 gb:L03840.1 NM_002011 fibroblast growth factor receptor 4 FGFR4 2264 NM_001291980 /// NM_002011 /// NM_022963 /// NM_213647 /// XM_005265837 /// XM_005265838 /// XR_427801 0001759 // organ induction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048554 // positive regulation of metalloenzyme activity // inferred from mutant phenotype /// 0055062 // phosphate ion homeostasis // inferred from sequence or structural similarity /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070857 // regulation of bile acid biosynthetic process // inferred from mutant phenotype /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 204580_at NM_002426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002426.1 /DEF=Homo sapiens matrix metalloproteinase 12 (macrophage elastase) (MMP12), mRNA. /FEA=mRNA /GEN=MMP12 /PROD=matrix metalloproteinase 12 preproprotein /DB_XREF=gi:4505206 /UG=Hs.1695 matrix metalloproteinase 12 (macrophage elastase) /FL=gb:L23808.1 gb:NM_002426.1 NM_002426 matrix metallopeptidase 12 (macrophage elastase) MMP12 4321 NM_002426 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0035313 // wound healing, spreading of epidermal cells // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004175 // endopeptidase activity // traceable author statement /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204581_at NM_001771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001771.1 /DEF=Homo sapiens CD22 antigen (CD22), mRNA. /FEA=mRNA /GEN=CD22 /PROD=CD22 antigen /DB_XREF=gi:4502650 /UG=Hs.171763 CD22 antigen /FL=gb:NM_001771.1 NM_001771 CD22 molecule CD22 933 NM_001185099 /// NM_001185100 /// NM_001185101 /// NM_001278417 /// NM_001771 /// NM_024916 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204582_s_at NM_001648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001648.1 /DEF=Homo sapiens kallikrein 3, (prostate specific antigen) (KLK3), mRNA. /FEA=mRNA /GEN=KLK3 /PROD=kallikrein 3, (prostate specific antigen) /DB_XREF=gi:4502172 /UG=Hs.171995 kallikrein 3, (prostate specific antigen) /FL=gb:BC005307.1 gb:NM_001648.1 gb:U17040.1 gb:M26663.1 NM_001648 kallikrein-related peptidase 3 KLK3 354 NM_001030047 /// NM_001030048 /// NM_001030049 /// NM_001030050 /// NM_001648 /// XM_006723195 /// XM_006723196 0006508 // proteolysis // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 204583_x_at U17040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17040.1 /DEF=Human prostate specific antigen precursor mRNA, complete cds. /FEA=mRNA /PROD=prostate specific antigen precursor /DB_XREF=gi:595945 /UG=Hs.171995 kallikrein 3, (prostate specific antigen) /FL=gb:BC005307.1 gb:NM_001648.1 gb:U17040.1 gb:M26663.1 U17040 kallikrein-related peptidase 3 KLK3 354 NM_001030047 /// NM_001030048 /// NM_001030049 /// NM_001030050 /// NM_001648 /// XM_006723195 /// XM_006723196 0006508 // proteolysis // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 204584_at AI653981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653981 /FEA=EST /DB_XREF=gi:4737960 /DB_XREF=est:ty04c03.x1 /CLONE=IMAGE:2278084 /UG=Hs.1757 L1 cell adhesion molecule (hydrocephalus, stenosis of aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling gait and adducted thumbs) syndrome, spastic paraplegia 1) /FL=gb:NM_024003.1 gb:NM_000425.2 gb:M77640.1 gb:M74387.1 AI653981 L1 cell adhesion molecule L1CAM 3897 NM_000425 /// NM_001143963 /// NM_001278116 /// NM_024003 0006935 // chemotaxis // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204585_s_at NM_000425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000425.2 /DEF=Homo sapiens L1 cell adhesion molecule (hydrocephalus, stenosis of aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling gait and adducted thumbs) syndrome, spastic paraplegia 1) (L1CAM), transcript variant 1, mRNA. /FEA=mRNA /GEN=L1CAM /PROD=L1 cell adhesion molecule, isoform 1 precursor /DB_XREF=gi:13435354 /UG=Hs.1757 L1 cell adhesion molecule (hydrocephalus, stenosis of aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling gait and adducted thumbs) syndrome, spastic paraplegia 1) /FL=gb:NM_024003.1 gb:NM_000425.2 gb:M77640.1 gb:M74387.1 NM_000425 L1 cell adhesion molecule L1CAM 3897 NM_000425 /// NM_001143963 /// NM_001278116 /// NM_024003 0006935 // chemotaxis // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204586_at NM_003458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003458.1 /DEF=Homo sapiens bassoon (presynaptic cytomatrix protein) (BSN), mRNA. /FEA=mRNA /GEN=BSN /PROD=bassoon (presynaptic cytomatrix protein) /DB_XREF=gi:4508018 /UG=Hs.194684 bassoon (presynaptic cytomatrix protein) /FL=gb:AF052224.1 gb:NM_003458.1 NM_003458 bassoon presynaptic cytomatrix protein BSN 8927 NM_003458 /// XM_006713380 0007268 // synaptic transmission // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 204587_at NM_003951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003951.2 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier, brain), member 14 (SLC25A14), transcript variant long, nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A14 /PROD=solute carrier family 25, member 14, isoformUCP5L /DB_XREF=gi:6006039 /UG=Hs.194686 solute carrier family 25 (mitochondrial carrier, brain), member 14 /FL=gb:AF155809.1 gb:AF155811.1 gb:NM_022810.1 gb:AF078544.1 gb:NM_003951.2 NM_003951 solute carrier family 25 (mitochondrial carrier, brain), member 14 SLC25A14 9016 NM_001282195 /// NM_001282196 /// NM_001282197 /// NM_001282198 /// NM_003951 /// NM_022810 /// NR_104107 /// XM_005262485 /// XM_005262488 /// XM_005262489 /// XM_006724786 /// XM_006724787 /// XM_006724788 /// XM_006724789 /// XR_244526 /// XR_430549 /// XR_430550 0006810 // transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 204588_s_at NM_003982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003982.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (SLC7A7), mRNA. /FEA=mRNA /GEN=SLC7A7 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 7 /DB_XREF=gi:4507054 /UG=Hs.194693 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 /FL=gb:BC003062.1 gb:AF092032.1 gb:NM_003982.1 gb:AB011263.1 NM_003982 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 SLC7A7 9056 NM_001126105 /// NM_001126106 /// NM_003982 /// NR_040448 /// XM_006720302 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation 204589_at NM_014840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014840.1 /DEF=Homo sapiens KIAA0537 gene product (KIAA0537), mRNA. /FEA=mRNA /GEN=KIAA0537 /PROD=KIAA0537 gene product /DB_XREF=gi:7662169 /UG=Hs.200598 KIAA0537 gene product /FL=gb:AB011109.1 gb:NM_014840.1 NM_014840 NUAK family, SNF1-like kinase, 1 NUAK1 9891 NM_014840 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 2000772 // regulation of cellular senescence // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204590_x_at NM_022916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022916.1 /DEF=Homo sapiens hypothetical protein similar to rat vacuolar sorting protein 33a (VPS33A), mRNA. /FEA=mRNA /GEN=VPS33A /PROD=hypothetical protein similar to rat vacuolarsorting protein 33a /DB_XREF=gi:12597662 /UG=Hs.206594 hypothetical protein similar to rat vacuolar sorting protein 33a /FL=gb:NM_022916.1 NM_022916 vacuolar protein sorting 33 homolog A (S. cerevisiae) VPS33A 65082 NM_022916 0006810 // transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0032400 // melanosome localization // inferred from direct assay /// 0032418 // lysosome localization // inferred from direct assay /// 0048070 // regulation of developmental pigmentation // inferred from sequence or structural similarity 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204591_at NM_006614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006614.1 /DEF=Homo sapiens cell adhesion molecule with homology to L1CAM (close homologue of L1) (CHL1), mRNA. /FEA=mRNA /GEN=CHL1 /PROD=cell adhesion molecule with homology to L1CAM(close homologue of L1) /DB_XREF=gi:5729766 /UG=Hs.210863 cell adhesion molecule with homology to L1CAM (close homologue of L1) /FL=gb:AF002246.1 gb:NM_006614.1 NM_006614 cell adhesion molecule L1-like CHL1 10752 NM_001253387 /// NM_001253388 /// NM_006614 /// NR_045572 /// XM_006712938 /// XM_006712939 /// XM_006712940 /// XM_006712941 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0035640 // exploration behavior // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204592_at NM_001365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001365.1 /DEF=Homo sapiens discs, large (Drosophila) homolog 4 (DLG4), mRNA. /FEA=mRNA /GEN=DLG4 /PROD=discs, large (Drosophila) homolog 4 /DB_XREF=gi:4557528 /UG=Hs.23731 discs, large (Drosophila) homolog 4 /FL=gb:U83192.1 gb:NM_001365.1 NM_001365 discs, large homolog 4 (Drosophila) DLG4 1742 NM_001128827 /// NM_001365 /// XM_005256489 /// XM_005256491 /// XM_005256492 /// XM_005256493 /// XM_005256494 /// XR_243545 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007612 // learning // traceable author statement /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from direct assay /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0050806 // positive regulation of synaptic transmission // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from electronic annotation /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from sequence or structural similarity /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // traceable author statement /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0032839 // dendrite cytoplasm // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0044309 // neuron spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031697 // beta-1 adrenergic receptor binding // inferred from sequence or structural similarity /// 0031748 // D1 dopamine receptor binding // inferred from sequence or structural similarity /// 0031812 // P2Y1 nucleotide receptor binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0033130 // acetylcholine receptor binding // inferred from sequence or structural similarity /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 204593_s_at AA046752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA046752 /FEA=EST /DB_XREF=gi:1524716 /DB_XREF=est:zf12e10.s1 /CLONE=IMAGE:376746 /UG=Hs.240062 hypothetical protein /FL=gb:U79252.1 gb:NM_013298.1 AA046752 mitochondrial elongation factor 1 MIEF1 54471 NM_019008 /// XM_005261652 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005777 // peroxisome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019003 // GDP binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 204594_s_at NM_013298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013298.1 /DEF=Homo sapiens hypothetical protein (HSU79252), mRNA. /FEA=mRNA /GEN=HSU79252 /PROD=hypothetical protein /DB_XREF=gi:9558736 /UG=Hs.240062 hypothetical protein /FL=gb:U79252.1 gb:NM_013298.1 NM_013298 mitochondrial elongation factor 1 MIEF1 54471 NM_019008 /// XM_005261652 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005777 // peroxisome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019003 // GDP binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 204595_s_at AI300520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI300520 /FEA=EST /DB_XREF=gi:3959866 /DB_XREF=est:qn55e06.x1 /CLONE=IMAGE:1902178 /UG=Hs.25590 stanniocalcin 1 /FL=gb:U46768.1 gb:U25997.1 gb:NM_003155.1 AI300520 stanniocalcin 1 STC1 6781 NM_003155 0001503 // ossification // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 204596_s_at U46768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46768.1 /DEF=Human stanniocalcin mRNA, complete cds. /FEA=mRNA /PROD=stanniocalcin /DB_XREF=gi:1199619 /UG=Hs.25590 stanniocalcin 1 /FL=gb:U46768.1 gb:U25997.1 gb:NM_003155.1 U46768 stanniocalcin 1 STC1 6781 NM_003155 0001503 // ossification // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 204597_x_at NM_003155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003155.1 /DEF=Homo sapiens stanniocalcin 1 (STC1), mRNA. /FEA=mRNA /GEN=STC1 /PROD=stanniocalcin 1 /DB_XREF=gi:4507264 /UG=Hs.25590 stanniocalcin 1 /FL=gb:U46768.1 gb:U25997.1 gb:NM_003155.1 NM_003155 stanniocalcin 1 STC1 6781 NM_003155 0001503 // ossification // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 204598_at NM_014948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014948.1 /DEF=Homo sapiens KIAA0860 protein (KIAA0860), mRNA. /FEA=mRNA /GEN=KIAA0860 /PROD=KIAA0860 protein /DB_XREF=gi:7662343 /UG=Hs.26009 KIAA0860 protein /FL=gb:BC000515.1 gb:AB020667.1 gb:NM_014948.1 NM_014948 U-box domain containing 5 UBOX5 22888 NM_001267584 /// NM_014948 /// NM_199415 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204599_s_at NM_006428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006428.1 /DEF=Homo sapiens melanoma-associated antigen recognised by cytotoxic T lymphocytes (MAAT1), mRNA. /FEA=mRNA /GEN=MAAT1 /PROD=melanoma-associated antigen recognised by Tlymphocytes /DB_XREF=gi:5453835 /UG=Hs.279869 melanoma-associated antigen recognised by cytotoxic T lymphocytes /FL=gb:BC000507.1 gb:BC000990.2 gb:NM_006428.1 gb:U19796.1 NM_006428 mitochondrial ribosomal protein L28 MRPL28 10573 NM_006428 /// XM_005255040 /// XM_005255041 0006412 // translation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204600_at NM_004443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004443.1 /DEF=Homo sapiens EphB3 (EPHB3) mRNA. /FEA=mRNA /GEN=EPHB3 /PROD=EphB3 /DB_XREF=gi:4758287 /UG=Hs.2913 EphB3 /FL=gb:NM_004443.1 NM_004443 EPH receptor B3 EPHB3 2049 NM_004443 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048546 // digestive tract morphogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204601_at NM_014664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014664.1 /DEF=Homo sapiens KIAA0615 gene product (KIAA0615), mRNA. /FEA=mRNA /GEN=KIAA0615 /PROD=KIAA0615 gene product /DB_XREF=gi:7662203 /UG=Hs.323712 KIAA0615 gene product /FL=gb:AB014515.1 gb:NM_014664.1 NM_014664 NEDD4 binding protein 1 N4BP1 9683 NM_153029 /// XM_005256262 /// XM_006721351 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 204602_at NM_012242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012242.1 /DEF=Homo sapiens dickkopf (Xenopus laevis) homolog 1 (DKK1), mRNA. /FEA=mRNA /GEN=DKK1 /PROD=dickkopf (Xenopus laevis) homolog 1 /DB_XREF=gi:7110718 /UG=Hs.40499 dickkopf (Xenopus laevis) homolog 1 /FL=gb:AF127563.1 gb:AF177394.1 gb:NM_012242.1 NM_012242 dickkopf WNT signaling pathway inhibitor 1 DKK1 22943 NM_012242 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002090 // regulation of receptor internalization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0042662 // negative regulation of mesodermal cell fate specification // inferred from direct assay /// 0042663 // regulation of endodermal cell fate specification // inferred from direct assay /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060323 // head morphogenesis // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0090082 // positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // inferred from direct assay /// 1901296 // negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment // inferred from direct assay /// 2000726 // negative regulation of cardiac muscle cell differentiation // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0048019 // receptor antagonist activity // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 204603_at NM_003686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003686.1 /DEF=Homo sapiens exonuclease 1 (EXO1), mRNA. /FEA=mRNA /GEN=EXO1 /PROD=Rad2 nuclease family member, homolog of S.cerevisiae exonuclease 1 /DB_XREF=gi:4504368 /UG=Hs.47504 exonuclease 1 /FL=gb:NM_006027.1 gb:AF042282.1 gb:AF060479.1 gb:AF091740.1 gb:AF084974.1 gb:NM_003686.1 NM_003686 exonuclease 1 EXO1 9156 NM_003686 /// NM_006027 /// NM_130398 /// XM_005273350 /// XM_006711840 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006298 // mismatch repair // inferred from physical interaction /// 0006298 // mismatch repair // inferred from sequence or structural similarity /// 0006310 // DNA recombination // inferred from genetic interaction /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // traceable author statement /// 0004527 // exonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008409 // 5'-3' exonuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0035312 // 5'-3' exodeoxyribonuclease activity // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from electronic annotation /// 0045145 // single-stranded DNA 5'-3' exodeoxyribonuclease activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048256 // flap endonuclease activity // inferred from direct assay /// 0051908 // double-stranded DNA 5'-3' exodeoxyribonuclease activity // inferred from direct assay 204604_at NM_012395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012395.1 /DEF=Homo sapiens PFTAIRE protein kinase 1 (PFTK1), mRNA. /FEA=mRNA /GEN=PFTK1 /PROD=PFTAIRE protein kinase 1 /DB_XREF=gi:6912583 /UG=Hs.57856 PFTAIRE protein kinase 1 /FL=gb:AB020641.1 gb:NM_012395.1 NM_012395 cyclin-dependent kinase 14 CDK14 5218 NM_001287135 /// NM_001287136 /// NM_001287137 /// NM_012395 /// XM_005250435 /// XM_005250436 /// XM_005250438 /// XM_005250439 /// XM_006716026 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0060828 // regulation of canonical Wnt signaling pathway // inferred from direct assay 0000308 // cytoplasmic cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 204605_at NM_006568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006568.1 /DEF=Homo sapiens cell growth regulatory with ring finger domain (CGR19), mRNA. /FEA=mRNA /GEN=CGR19 /PROD=cell growth regulatory with ring finger domain /DB_XREF=gi:5729764 /UG=Hs.59106 cell growth regulatory with ring finger domain /FL=gb:U66469.1 gb:NM_006568.1 NM_006568 cell growth regulator with ring finger domain 1 CGRRF1 10668 NM_006568 0006950 // response to stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204606_at NM_002989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002989.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 21 (SCYA21), mRNA. /FEA=mRNA /GEN=SCYA21 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 21 /DB_XREF=gi:4506834 /UG=Hs.57907 small inducible cytokine subfamily A (Cys-Cys), member 21 /FL=gb:U88320.1 gb:AB002409.1 gb:AF001979.1 gb:NM_002989.1 NM_002989 chemokine (C-C motif) ligand 21 CCL21 6366 NM_002989 0001768 // establishment of T cell polarity // inferred from direct assay /// 0001771 // immunological synapse formation // inferred from sequence or structural similarity /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002407 // dendritic cell chemotaxis // inferred from direct assay /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from sequence or structural similarity /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from direct assay /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034695 // response to prostaglandin E // inferred from direct assay /// 0035759 // mesangial cell-matrix adhesion // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 0097026 // dendritic cell dendrite assembly // inferred from sequence or structural similarity /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000147 // positive regulation of cell motility // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay /// 2000529 // positive regulation of myeloid dendritic cell chemotaxis // inferred from direct assay /// 2000548 // negative regulation of dendritic cell dendrite assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0031732 // CCR7 chemokine receptor binding // inferred from sequence or structural similarity /// 0042379 // chemokine receptor binding // inferred from direct assay 204607_at NM_005518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005518.1 /DEF=Homo sapiens 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) (HMGCS2), mRNA. /FEA=mRNA /GEN=HMGCS2 /PROD=3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2(mitochondrial) /DB_XREF=gi:5031750 /UG=Hs.59889 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) /FL=gb:NM_005518.1 NM_005518 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) HMGCS2 3158 NM_001166107 /// NM_005518 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004421 // hydroxymethylglutaryl-CoA synthase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204608_at NM_000048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000048.1 /DEF=Homo sapiens argininosuccinate lyase (ASL), mRNA. /FEA=mRNA /GEN=ASL /PROD=argininosuccinate lyase /DB_XREF=gi:4502256 /UG=Hs.61258 argininosuccinate lyase /FL=gb:M14218.1 gb:J03058.1 gb:M57638.1 gb:NM_000048.1 NM_000048 argininosuccinate lyase ASL 435 NM_000048 /// NM_001024943 /// NM_001024944 /// NM_001024946 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006526 // arginine biosynthetic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019676 // ammonia assimilation cycle // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042450 // arginine biosynthetic process via ornithine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004056 // argininosuccinate lyase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 204609_at AI583181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI583181 /FEA=EST /DB_XREF=gi:4569078 /DB_XREF=est:tq64f01.x1 /CLONE=IMAGE:2213593 /UG=Hs.66713 hepatitis delta antigen-interacting protein A /FL=gb:U63825.1 gb:NM_006848.1 AI583181 coiled-coil domain containing 85B CCDC85B 11007 NM_006848 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204610_s_at NM_006848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006848.1 /DEF=Homo sapiens hepatitis delta antigen-interacting protein A (DIPA), mRNA. /FEA=mRNA /GEN=DIPA /PROD=hepatitis delta antigen-interacting protein A /DB_XREF=gi:5803004 /UG=Hs.66713 hepatitis delta antigen-interacting protein A /FL=gb:U63825.1 gb:NM_006848.1 NM_006848 coiled-coil domain containing 85B CCDC85B 11007 NM_006848 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204611_s_at NM_006244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006244.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), beta isoform (PPP2R5B), mRNA. /FEA=mRNA /GEN=PPP2R5B /PROD=protein phosphatase 2, regulatory subunit B(B56), beta isoform /DB_XREF=gi:5453951 /UG=Hs.75199 protein phosphatase 2, regulatory subunit B (B56), beta isoform /FL=gb:L42374.1 gb:NM_006244.1 NM_006244 protein phosphatase 2, regulatory subunit B', beta PPP2R5B 5526 NM_006244 /// XM_006718606 /// XM_006718607 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 204612_at NM_006823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006823.1 /DEF=Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), mRNA. /FEA=mRNA /GEN=PKIA /PROD=protein kinase, cAMP-dependent, catalytic,inhibitor alpha /DB_XREF=gi:5803126 /UG=Hs.75209 protein kinase (cAMP-dependent, catalytic) inhibitor alpha /FL=gb:NM_006823.1 NM_006823 protein kinase (cAMP-dependent, catalytic) inhibitor alpha PKIA 5569 NM_006823 /// NM_181839 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0004862 // cAMP-dependent protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 204613_at NM_002661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002661.1 /DEF=Homo sapiens phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2), mRNA. /FEA=mRNA /GEN=PLCG2 /PROD=phospholipase C, gamma 2(phosphatidylinositol-specific) /DB_XREF=gi:4505870 /UG=Hs.75648 phospholipase C, gamma 2 (phosphatidylinositol-specific) /FL=gb:M37238.1 gb:NM_002661.1 NM_002661 phospholipase C, gamma 2 (phosphatidylinositol-specific) PLCG2 5336 NM_002661 /// XR_243482 /// XR_248240 /// XR_253577 0002316 // follicular B cell differentiation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0032237 // activation of store-operated calcium channel activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032959 // inositol trisphosphate biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204614_at NM_002575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002575.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 (SERPINB2), mRNA. /FEA=mRNA /GEN=SERPINB2 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 2 /DB_XREF=gi:4505594 /UG=Hs.75716 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 /FL=gb:J02685.1 gb:J03603.1 gb:M18082.1 gb:NM_002575.1 NM_002575 serpin peptidase inhibitor, clade B (ovalbumin), member 2 SERPINB2 5055 NM_001143818 /// NM_002575 0007596 // blood coagulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0042060 // wound healing // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 204615_x_at NM_004508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004508.1 /DEF=Homo sapiens isopentenyl-diphosphate delta isomerase (IDI1), mRNA. /FEA=mRNA /GEN=IDI1 /PROD=isopentenyl-diphosphate delta isomerase /DB_XREF=gi:4758583 /UG=Hs.76038 isopentenyl-diphosphate delta isomerase /FL=gb:NM_004508.1 NM_004508 isopentenyl-diphosphate delta isomerase 1 IDI1 3422 NM_004508 /// XM_005252445 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050992 // dimethylallyl diphosphate biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from direct assay /// 0004452 // isopentenyl-diphosphate delta-isomerase activity // inferred from direct assay /// 0004452 // isopentenyl-diphosphate delta-isomerase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204616_at NM_006002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006002.1 /DEF=Homo sapiens ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (UCHL3), mRNA. /FEA=mRNA /GEN=UCHL3 /PROD=ubiquitin carboxyl-terminal esterase L3(ubiquitin thiolesterase) /DB_XREF=gi:5174740 /UG=Hs.77917 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) /FL=gb:M30496.1 gb:NM_006002.1 NM_006002 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) UCHL3 7347 NM_001270952 /// NM_006002 /// XM_005266514 /// XM_005266515 /// XM_006719863 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay 204617_s_at NM_022914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022914.1 /DEF=Homo sapiens hypothetical protein 24432 (24432), mRNA. /FEA=mRNA /GEN=24432 /PROD=hypothetical protein 24432 /DB_XREF=gi:12597658 /UG=Hs.78019 hypothetical protein 24432 /FL=gb:NM_022914.1 NM_022914 adrenocortical dysplasia homolog (mouse) ACD 65057 NM_001082486 /// NM_001082487 /// NM_022914 /// XM_005256115 /// XR_429727 /// XR_429728 0000723 // telomere maintenance // inferred from direct assay /// 0000723 // telomere maintenance // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // inferred from electronic annotation /// 0016233 // telomere capping // inferred from genetic interaction /// 0016233 // telomere capping // non-traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0031848 // protection from non-homologous end joining at telomere // inferred from sequence or structural similarity /// 0032202 // telomere assembly // inferred from mutant phenotype /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0035282 // segmentation // inferred from electronic annotation /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0060381 // positive regulation of single-stranded telomeric DNA binding // inferred from direct assay /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005697 // telomerase holoenzyme complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from electronic annotation /// 0070182 // DNA polymerase binding // inferred from physical interaction 204618_s_at NM_005254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005254.2 /DEF=Homo sapiens GA-binding protein transcription factor, beta subunit 1 (53kD) (GABPB1), transcript variant beta, mRNA. /FEA=mRNA /GEN=GABPB1 /PROD=GA-binding protein transcription factor, betasubunit 1 (53kD), isoform beta 1 /DB_XREF=gi:8051592 /UG=Hs.78915 GA-binding protein transcription factor, beta subunit 1 (53kD) /FL=gb:U13045.1 gb:NM_005254.2 NM_005254 GA binding protein transcription factor, beta subunit 1 GABPB1 2553 NM_002041 /// NM_005254 /// NM_016654 /// NM_016655 /// NM_181427 /// XM_005254273 /// XM_005254274 /// XM_006720455 /// XM_006720456 /// XM_006720457 /// XM_006720458 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 204619_s_at BF590263 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF590263 /FEA=EST /DB_XREF=gi:11682587 /DB_XREF=est:nab22b12.x1 /CLONE=IMAGE:3266638 /UG=Hs.81800 chondroitin sulfate proteoglycan 2 (versican) /FL=gb:NM_004385.1 BF590263 versican VCAN 1462 NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385 0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 204620_s_at NM_004385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004385.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan 2 (versican) (CSPG2), mRNA. /FEA=mRNA /GEN=CSPG2 /PROD=chondroitin sulfate proteoglycan 2 (versican) /DB_XREF=gi:4758081 /UG=Hs.81800 chondroitin sulfate proteoglycan 2 (versican) /FL=gb:NM_004385.1 NM_004385 versican VCAN 1462 NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385 0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 204621_s_at AI935096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935096 /FEA=EST /DB_XREF=gi:5673966 /DB_XREF=est:wp13e10.x1 /CLONE=IMAGE:2464746 /UG=Hs.82120 nuclear receptor subfamily 4, group A, member 2 /FL=gb:NM_006186.1 AI935096 nuclear receptor subfamily 4, group A, member 2 NR4A2 4929 NM_006186 /// NM_173171 /// NM_173172 /// NM_173173 /// XM_005246621 /// XM_005246622 /// XM_005246623 /// XM_006712553 /// XR_427087 0001666 // response to hypoxia // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016265 // death // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0021986 // habenula development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031668 // cellular response to extracellular stimulus // inferred from direct assay /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051866 // general adaptation syndrome // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204622_x_at NM_006186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006186.1 /DEF=Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), mRNA. /FEA=mRNA /GEN=NR4A2 /PROD=nuclear receptor subfamily 4, group A, member 2 /DB_XREF=gi:5453821 /UG=Hs.82120 nuclear receptor subfamily 4, group A, member 2 /FL=gb:NM_006186.1 NM_006186 nuclear receptor subfamily 4, group A, member 2 NR4A2 4929 NM_006186 /// NM_173171 /// NM_173172 /// NM_173173 /// XM_005246621 /// XM_005246622 /// XM_005246623 /// XM_006712553 /// XR_427087 0001666 // response to hypoxia // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016265 // death // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0021986 // habenula development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031668 // cellular response to extracellular stimulus // inferred from direct assay /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051866 // general adaptation syndrome // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204623_at NM_003226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003226.1 /DEF=Homo sapiens trefoil factor 3 (intestinal) (TFF3), mRNA. /FEA=mRNA /GEN=TFF3 /PROD=trefoil factor 3 (intestinal) /DB_XREF=gi:4507452 /UG=Hs.82961 trefoil factor 3 (intestinal) /FL=gb:L08044.1 gb:L15203.1 gb:NM_003226.1 NM_003226 trefoil factor 3 (intestinal) TFF3 7033 NM_003226 0006952 // defense response // traceable author statement /// 0007586 // digestion // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0032579 // apical lamina of hyaline layer // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 204624_at NM_000053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000053.1 /DEF=Homo sapiens ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (ATP7B), mRNA. /FEA=mRNA /GEN=ATP7B /PROD=ATPase, Cu++ transporting, beta polypeptide(Wilson disease) /DB_XREF=gi:4502322 /UG=Hs.84999 ATPase, Cu++ transporting, beta polypeptide (Wilson disease) /FL=gb:U03464.1 gb:NM_000053.1 gb:U11700.1 NM_000053 ATPase, Cu++ transporting, beta polypeptide ATP7B 540 NM_000053 /// NM_001005918 /// NM_001243182 /// XM_005266423 /// XM_005266424 /// XM_005266427 /// XM_005266428 /// XM_005266429 /// XM_005266430 /// XM_005266431 /// XM_005266432 /// XM_006719837 /// XM_006719838 /// XM_006719839 /// XR_429217 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from genetic interaction /// 0006878 // cellular copper ion homeostasis // traceable author statement /// 0006882 // cellular zinc ion homeostasis // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015677 // copper ion import // inferred from direct assay /// 0015680 // intracellular copper ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0046688 // response to copper ion // inferred from direct assay /// 0051208 // sequestering of calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0060003 // copper ion export // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004008 // copper-exporting ATPase activity // non-traceable author statement /// 0004008 // copper-exporting ATPase activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0043682 // copper-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204625_s_at BF115658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF115658 /FEA=EST /DB_XREF=gi:10985134 /DB_XREF=est:7n82b10.x1 /CLONE=IMAGE:3571146 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) /FL=gb:J02703.1 gb:M35999.1 gb:M20311.1 gb:NM_000212.1 BF115658 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 204626_s_at J02703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02703.1 /DEF=Human endothelial membrane glycoprotein IIIa (GPIIIa) mRNA, complete cds. /FEA=mRNA /GEN=ITGB3 /DB_XREF=gi:183452 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) /FL=gb:J02703.1 gb:M35999.1 gb:M20311.1 gb:NM_000212.1 J02703 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 204627_s_at M35999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M35999.1 /DEF=Human platelet glycoprotein IIIa (GPIIIa) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183532 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) /FL=gb:J02703.1 gb:M35999.1 gb:M20311.1 gb:NM_000212.1 M35999 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 204628_s_at NM_000212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000212.1 /DEF=Homo sapiens integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), mRNA. /FEA=mRNA /GEN=ITGB3 /PROD=integrin beta chain, beta 3 precursor /DB_XREF=gi:4557676 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) /FL=gb:J02703.1 gb:M35999.1 gb:M20311.1 gb:NM_000212.1 NM_000212 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 204629_at NM_013327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013327.1 /DEF=Homo sapiens CGI-56 protein (CGI-56), mRNA. /FEA=mRNA /GEN=CGI-56 /PROD=CGI-56 protein /DB_XREF=gi:7019346 /UG=Hs.8836 beta-parvin /FL=gb:AF237769.1 gb:AF151814.1 gb:NM_013327.1 NM_013327 parvin, beta PARVB 29780 NM_001003828 /// NM_001243385 /// NM_001243386 /// NM_013327 /// XM_005261593 /// XM_005261594 /// XM_005261595 /// XM_005261596 /// XM_006724236 0007155 // cell adhesion // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0071963 // establishment or maintenance of cell polarity regulating cell shape // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204630_s_at NM_004871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004871.1 /DEF=Homo sapiens golgi SNAP receptor complex member 1 (GOSR1), mRNA. /FEA=mRNA /GEN=GOSR1 /PROD=golgi SNAP receptor complex member 1 /DB_XREF=gi:4758455 /UG=Hs.8868 golgi SNAP receptor complex member 1 /FL=gb:AF073926.1 gb:NM_004871.1 NM_004871 golgi SNAP receptor complex member 1 GOSR1 9527 NM_001007024 /// NM_001007025 /// NM_004871 /// XM_005258070 /// XM_005258071 /// XM_005258072 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement 0005484 // SNAP receptor activity // inferred from direct assay 204631_at NM_017534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017534.1 /DEF=Homo sapiens myosin, heavy polypeptide 2, skeletal muscle, adult (MYH2), mRNA. /FEA=mRNA /GEN=MYH2 /PROD=myosin, heavy polypeptide 2, skeletal muscle,adult /DB_XREF=gi:8923939 /UG=Hs.931 myosin, heavy polypeptide 2, skeletal muscle, adult /FL=gb:AF111784.1 gb:NM_017534.1 NM_017534 myosin, heavy chain 2, skeletal muscle, adult MYH2 4620 NM_001100112 /// NM_017534 0001778 // plasma membrane repair // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from direct assay /// 0006936 // muscle contraction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0014823 // response to activity // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030049 // muscle filament sliding // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005826 // actomyosin contractile ring // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005859 // muscle myosin complex // non-traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from direct assay /// 0030017 // sarcomere // non-traceable author statement /// 0031672 // A band // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000146 // microfilament motor activity // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement 204632_at NM_003942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003942.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 90kD, polypeptide 4 (RPS6KA4), mRNA. /FEA=mRNA /GEN=RPS6KA4 /PROD=ribosomal protein S6 kinase, 90kD, polypeptide4 /DB_XREF=gi:4506734 /UG=Hs.105584 ribosomal protein S6 kinase, 90kD, polypeptide 4 /FL=gb:NM_003942.1 NM_003942 ribosomal protein S6 kinase, 90kDa, polypeptide 4 RPS6KA4 8986 NM_001006944 /// NM_003942 /// XM_005274379 /// XM_005274380 /// XM_005274381 /// XM_006718735 0001818 // negative regulation of cytokine production // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // traceable author statement /// 0032793 // positive regulation of CREB transcription factor activity // traceable author statement /// 0033129 // positive regulation of histone phosphorylation // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043987 // histone H3-S10 phosphorylation // inferred from mutant phenotype /// 0043988 // histone H3-S28 phosphorylation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004711 // ribosomal protein S6 kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from genetic interaction 204633_s_at AF074393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074393.1 /DEF=Homo sapiens nuclear mitogen- and stress-activated protein kinase-1 (MSK1) mRNA, complete cds. /FEA=mRNA /GEN=MSK1 /PROD=nuclear mitogen- and stress-activated proteinkinase-1 /DB_XREF=gi:3411156 /UG=Hs.109058 ribosomal protein S6 kinase, 90kD, polypeptide 5 /FL=gb:AF074393.1 gb:AF090421.1 gb:AF080000.1 gb:NM_004755.1 AF074393 ribosomal protein S6 kinase, 90kDa, polypeptide 5 RPS6KA5 9252 NM_004755 /// NM_182398 0001818 // negative regulation of cytokine production // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0016572 // histone phosphorylation // traceable author statement /// 0032793 // positive regulation of CREB transcription factor activity // traceable author statement /// 0033129 // positive regulation of histone phosphorylation // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043987 // histone H3-S10 phosphorylation // inferred from mutant phenotype /// 0043988 // histone H3-S28 phosphorylation // inferred from mutant phenotype /// 0043990 // histone H2A-S1 phosphorylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204634_at NM_003157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003157.1 /DEF=Homo sapiens serinethreonine kinase 2 (STK2), mRNA. /FEA=mRNA /GEN=STK2 /PROD=serinethreonine kinase 2 /DB_XREF=gi:4507276 /UG=Hs.1087 serinethreonine kinase 2 /FL=gb:L20321.1 gb:NM_003157.1 NM_003157 NIMA-related kinase 4 NEK4 6787 NM_001193533 /// NM_003157 /// XM_006713310 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204635_at NM_004755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004755.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 90kD, polypeptide 5 (RPS6KA5), mRNA. /FEA=mRNA /GEN=RPS6KA5 /PROD=ribosomal protein S6 kinase, 90kD, polypeptide5 /DB_XREF=gi:4759051 /UG=Hs.109058 ribosomal protein S6 kinase, 90kD, polypeptide 5 /FL=gb:AF074393.1 gb:AF090421.1 gb:AF080000.1 gb:NM_004755.1 NM_004755 ribosomal protein S6 kinase, 90kDa, polypeptide 5 RPS6KA5 9252 NM_004755 /// NM_182398 0001818 // negative regulation of cytokine production // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0016572 // histone phosphorylation // traceable author statement /// 0032793 // positive regulation of CREB transcription factor activity // traceable author statement /// 0033129 // positive regulation of histone phosphorylation // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043987 // histone H3-S10 phosphorylation // inferred from mutant phenotype /// 0043988 // histone H3-S28 phosphorylation // inferred from mutant phenotype /// 0043990 // histone H2A-S1 phosphorylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204636_at NM_000494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000494.1 /DEF=Homo sapiens collagen, type XVII, alpha 1 (COL17A1), mRNA. /FEA=mRNA /GEN=COL17A1 /PROD=collagen, type XVII, alpha 1 /DB_XREF=gi:4502942 /UG=Hs.117938 collagen, type XVII, alpha 1 /FL=gb:NM_000494.1 NM_000494 collagen, type XVII, alpha 1 COL17A1 1308 NM_000494 /// NM_130778 0007160 // cell-matrix adhesion // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204637_at NM_000735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000735.2 /DEF=Homo sapiens glycoprotein hormones, alpha polypeptide (CGA), mRNA. /FEA=mRNA /GEN=CGA /PROD=glycoprotein hormones, alpha polypeptideprecursor /DB_XREF=gi:10800407 /UG=Hs.119689 glycoprotein hormones, alpha polypeptide /FL=gb:NM_000735.2 NM_000735 glycoprotein hormones, alpha polypeptide CGA 1081 NM_000735 /// NM_001252383 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008406 // gonad development // inferred from electronic annotation /// 0016486 // peptide hormone processing // traceable author statement /// 0030335 // positive regulation of cell migration // non-traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032275 // luteinizing hormone secretion // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046884 // follicle-stimulating hormone secretion // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204638_at NM_001611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001611.2 /DEF=Homo sapiens acid phosphatase 5, tartrate resistant (ACP5), mRNA. /FEA=mRNA /GEN=ACP5 /PROD=tartrate resistant acid phosphatase 5 precursor /DB_XREF=gi:6138970 /UG=Hs.1211 acid phosphatase 5, tartrate resistant /FL=gb:J04430.1 gb:NM_001611.2 NM_001611 acid phosphatase 5, tartrate resistant ACP5 54 NM_001111034 /// NM_001111035 /// NM_001111036 /// NM_001611 /// XM_005259938 /// XM_005259939 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032929 // negative regulation of superoxide anion generation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // traceable author statement /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008199 // ferric iron binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204639_at NM_000022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000022.1 /DEF=Homo sapiens adenosine deaminase (ADA), mRNA. /FEA=mRNA /GEN=ADA /PROD=adenosine deaminase /DB_XREF=gi:4557248 /UG=Hs.1217 adenosine deaminase /FL=gb:K02567.1 gb:NM_000022.1 NM_000022 adenosine deaminase ADA 100 NM_000022 /// XM_005260236 /// XM_006723679 /// XR_244129 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002314 // germinal center B cell differentiation // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0002686 // negative regulation of leukocyte migration // inferred from electronic annotation /// 0002906 // negative regulation of mature B cell apoptotic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006154 // adenosine catabolic process // inferred from direct assay /// 0006154 // adenosine catabolic process // inferred from sequence or structural similarity /// 0006157 // deoxyadenosine catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032261 // purine nucleotide salvage // inferred from mutant phenotype /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042323 // negative regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0043103 // hypoxanthine salvage // not recorded /// 0043278 // response to morphine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046061 // dATP catabolic process // inferred from electronic annotation /// 0046101 // hypoxanthine biosynthetic process // inferred from electronic annotation /// 0046103 // inosine biosynthetic process // inferred from direct assay /// 0046103 // inosine biosynthetic process // inferred from sequence or structural similarity /// 0046111 // xanthine biosynthetic process // inferred from electronic annotation /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060169 // negative regulation of adenosine receptor signaling pathway // inferred from direct assay /// 0060407 // negative regulation of penile erection // inferred from electronic annotation /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070256 // negative regulation of mucus secretion // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0060205 // cytoplasmic membrane-bounded vesicle lumen // inferred from electronic annotation 0001883 // purine nucleoside binding // inferred from electronic annotation /// 0004000 // adenosine deaminase activity // inferred from direct assay /// 0004000 // adenosine deaminase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204640_s_at NM_003563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003563.1 /DEF=Homo sapiens speckle-type POZ protein (SPOP), mRNA. /FEA=mRNA /GEN=SPOP /PROD=speckle-type POZ protein /DB_XREF=gi:4507182 /UG=Hs.129951 speckle-type POZ protein /FL=gb:BC003385.1 gb:NM_003563.1 NM_003563 speckle-type POZ protein SPOP 8405 NM_001007226 /// NM_001007227 /// NM_001007228 /// NM_001007229 /// NM_001007230 /// NM_003563 /// XM_005257723 /// XM_005257724 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 204641_at NM_002497 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002497.1 /DEF=Homo sapiens NIMA (never in mitosis gene a)-related kinase 2 (NEK2), mRNA. /FEA=mRNA /GEN=NEK2 /PROD=NIMA (never in mitosis gene a)-related kinase 2 /DB_XREF=gi:4505372 /UG=Hs.153704 NIMA (never in mitosis gene a)-related kinase 2 /FL=gb:NM_002497.1 gb:U11050.1 NM_002497 NIMA-related kinase 2 NEK2 4751 NM_001204182 /// NM_001204183 /// NM_002497 /// XM_005273147 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from direct assay /// 0007067 // mitotic nuclear division // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0046602 // regulation of mitotic centrosome separation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051225 // spindle assembly // traceable author statement /// 0051299 // centrosome separation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from electronic annotation /// 1903126 // negative regulation of centriole-centriole cohesion // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204642_at NM_001400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001400.2 /DEF=Homo sapiens endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 (EDG1), mRNA. /FEA=mRNA /GEN=EDG1 /PROD=endothelial differentiation, sphingolipidG-protein-coupled receptor, 1 /DB_XREF=gi:13027635 /UG=Hs.154210 endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 /FL=gb:NM_001400.2 gb:M31210.1 gb:AF233365.1 NM_001400 sphingosine-1-phosphate receptor 1 S1PR1 1901 NM_001400 /// XM_006710399 0001525 // angiogenesis // inferred from electronic annotation /// 0001955 // blood vessel maturation // inferred from sequence or structural similarity /// 0003245 // cardiac muscle tissue growth involved in heart morphogenesis // inferred from sequence or structural similarity /// 0003376 // sphingosine-1-phosphate signaling pathway // inferred from direct assay /// 0006935 // chemotaxis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from electronic annotation /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 0072678 // T cell migration // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0038036 // sphingosine-1-phosphate receptor activity // inferred from direct assay /// 0046625 // sphingolipid binding // inferred from electronic annotation 204643_s_at NM_006375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006375.1 /DEF=Homo sapiens cytosolic ovarian carcinoma antigen 1 (COVA1), mRNA. /FEA=mRNA /GEN=COVA1 /PROD=cytosolic ovarian carcinoma antigen 1 /DB_XREF=gi:5453550 /UG=Hs.155185 cytosolic ovarian carcinoma antigen 1 /FL=gb:NM_006375.1 gb:AF207881.1 NM_006375 ecto-NOX disulfide-thiol exchanger 2 ENOX2 10495 NM_001281736 /// NM_006375 /// NM_182314 /// XM_005262354 /// XM_005262355 0007624 // ultradian rhythm // inferred from direct assay /// 0016049 // cell growth // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 204644_at AF207881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF207881.1 /DEF=Homo sapiens tumor-associated hydroquinone (NADH) oxidase tNOX mRNA, complete cds. /FEA=mRNA /PROD=tumor-associated hydroquinone (NADH) oxidasetNOX /DB_XREF=gi:6644166 /UG=Hs.155185 cytosolic ovarian carcinoma antigen 1 /FL=gb:NM_006375.1 gb:AF207881.1 AF207881 ecto-NOX disulfide-thiol exchanger 2 ENOX2 10495 NM_001281736 /// NM_006375 /// NM_182314 /// XM_005262354 /// XM_005262355 0007624 // ultradian rhythm // inferred from direct assay /// 0016049 // cell growth // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 204645_at NM_001241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001241.1 /DEF=Homo sapiens cyclin T2 (CCNT2), mRNA. /FEA=mRNA /GEN=CCNT2 /PROD=cyclin T2 /DB_XREF=gi:4502628 /UG=Hs.155478 cyclin T2 /FL=gb:AF048731.1 gb:NM_001241.1 NM_001241 cyclin T2 CCNT2 905 NM_001241 /// NM_058241 /// NR_037649 /// XM_005263830 /// XM_005263831 /// XM_005263832 /// XM_006712827 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0019901 // protein kinase binding // inferred from electronic annotation 204646_at NM_000110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000110.2 /DEF=Homo sapiens dihydropyrimidine dehydrogenase (DPYD), mRNA. /FEA=mRNA /GEN=DPYD /PROD=dihydropyrimidine dehydrogenase /DB_XREF=gi:4557874 /UG=Hs.1602 dihydropyrimidine dehydrogenase /FL=gb:U20938.1 gb:NM_000110.2 gb:U09178.1 gb:AB003063.1 NM_000110 dihydropyrimidine dehydrogenase DPYD 1806 NM_000110 /// NM_001160301 /// XM_005270562 /// XM_006710397 0006145 // purine nucleobase catabolic process // inferred from mutant phenotype /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from mutant phenotype /// 0006208 // pyrimidine nucleobase catabolic process // inferred from sequence or structural similarity /// 0006210 // thymine catabolic process // inferred from direct assay /// 0006212 // uracil catabolic process // inferred from direct assay /// 0006214 // thymidine catabolic process // inferred from direct assay /// 0006222 // UMP biosynthetic process // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0019483 // beta-alanine biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004152 // dihydroorotate dehydrogenase activity // inferred from electronic annotation /// 0004158 // dihydroorotate oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017113 // dihydropyrimidine dehydrogenase (NADP+) activity // inferred from direct assay /// 0017113 // dihydropyrimidine dehydrogenase (NADP+) activity // inferred from mutant phenotype /// 0017113 // dihydropyrimidine dehydrogenase (NADP+) activity // inferred from sequence or structural similarity /// 0017113 // dihydropyrimidine dehydrogenase (NADP+) activity // traceable author statement /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0050661 // NADP binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 204647_at NM_004838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004838.1 /DEF=Homo sapiens Homer, neuronal immediate early gene, 3 (HOMER-3), mRNA. /FEA=mRNA /GEN=HOMER-3 /PROD=Homer, neuronal immediate early gene, 3 /DB_XREF=gi:4758549 /UG=Hs.166146 Homer, neuronal immediate early gene, 3 /FL=gb:AF093265.1 gb:NM_004838.1 NM_004838 homer homolog 3 (Drosophila) HOMER3 9454 NM_001145721 /// NM_001145722 /// NM_001145724 /// NM_004838 /// NR_027297 /// XM_006722943 /// XM_006722944 0006605 // protein targeting // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 204648_at NM_000906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000906.1 /DEF=Homo sapiens natriuretic peptide receptor Aguanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1), mRNA. /FEA=mRNA /GEN=NPR1 /PROD=natriuretic peptide receptor Aguanylate cyclaseA (atrionatriuretic peptide receptor A) /DB_XREF=gi:4505434 /UG=Hs.167382 natriuretic peptide receptor Aguanylate cyclase A (atrionatriuretic peptide receptor A) /FL=gb:NM_000906.1 NM_000906 natriuretic peptide receptor 1 NPR1 4881 NM_000906 /// XM_005245218 /// XM_006711342 /// XM_006711343 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007589 // body fluid secretion // traceable author statement /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // traceable author statement /// 0035815 // positive regulation of renal sodium excretion // traceable author statement /// 0042312 // regulation of vasodilation // non-traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0043114 // regulation of vascular permeability // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // non-traceable author statement /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction 204649_at NM_005480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005480.1 /DEF=Homo sapiens trophinin associated protein (tastin) (TROAP), mRNA. /FEA=mRNA /GEN=TROAP /PROD=trophinin associated protein (tastin) /DB_XREF=gi:4885624 /UG=Hs.171955 trophinin associated protein (tastin) /FL=gb:NM_005480.1 gb:U04810.1 NM_005480 trophinin associated protein TROAP 10024 NM_001100620 /// NM_001278324 /// NM_005480 /// XM_006719181 /// XM_006719182 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204650_s_at NM_006051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006051.1 /DEF=Homo sapiens FE65-LIKE 2 (FE65L2), mRNA. /FEA=mRNA /GEN=FE65L2 /PROD=FE65-LIKE 2 /DB_XREF=gi:5174436 /UG=Hs.173103 FE65-LIKE 2 /FL=gb:AB018247.1 gb:NM_006051.1 gb:AF224709.1 gb:AF224710.1 NM_006051 amyloid beta (A4) precursor protein-binding, family B, member 3 /// microRNA 6831 APBB3 /// MIR6831 10307 /// 102465499 NM_006051 /// NM_133172 /// NM_133173 /// NM_133174 /// NM_133175 /// NM_133176 /// NR_106889 0035556 // intracellular signal transduction // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204651_at AW003022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003022 /FEA=EST /DB_XREF=gi:5849860 /DB_XREF=est:wq61d03.x1 /CLONE=IMAGE:2475749 /UG=Hs.180069 nuclear respiratory factor 1 /FL=gb:U02683.1 gb:NM_005011.1 AW003022 nuclear respiratory factor 1 NRF1 4899 NM_001040110 /// NM_001293163 /// NM_001293164 /// NM_005011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation 204652_s_at NM_005011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005011.1 /DEF=Homo sapiens nuclear respiratory factor 1 (NRF1), mRNA. /FEA=mRNA /GEN=NRF1 /PROD=nuclear respiratory factor 1 /DB_XREF=gi:4826865 /UG=Hs.180069 nuclear respiratory factor 1 /FL=gb:U02683.1 gb:NM_005011.1 NM_005011 nuclear respiratory factor 1 NRF1 4899 NM_001040110 /// NM_001293163 /// NM_001293164 /// NM_005011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation 204653_at BF343007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF343007 /FEA=EST /DB_XREF=gi:11290124 /DB_XREF=est:602017119F1 /CLONE=IMAGE:4152580 /UG=Hs.18387 transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) /FL=gb:M36711.1 gb:NM_003220.1 BF343007 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) TFAP2A 7020 NM_001032280 /// NM_001042425 /// NM_003220 /// XM_006715175 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001822 // kidney development // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0003404 // optic vesicle morphogenesis // inferred from sequence or structural similarity /// 0003409 // optic cup structural organization // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007423 // sensory organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010842 // retina layer formation // inferred from expression pattern /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0021506 // anterior neuropore closure // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021623 // oculomotor nerve formation // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from electronic annotation /// 0070172 // positive regulation of tooth mineralization // inferred from direct assay /// 0071281 // cellular response to iron ion // inferred from direct assay /// 0071711 // basement membrane organization // inferred from electronic annotation /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 204654_s_at NM_003220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003220.1 /DEF=Homo sapiens transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) (TFAP2A), mRNA. /FEA=mRNA /GEN=TFAP2A /PROD=transcription factor AP-2 alpha (activatingenhancer-binding protein 2 alpha) /DB_XREF=gi:4507440 /UG=Hs.18387 transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) /FL=gb:M36711.1 gb:NM_003220.1 NM_003220 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) TFAP2A 7020 NM_001032280 /// NM_001042425 /// NM_003220 /// XM_006715175 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001822 // kidney development // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0003404 // optic vesicle morphogenesis // inferred from sequence or structural similarity /// 0003409 // optic cup structural organization // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007423 // sensory organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010842 // retina layer formation // inferred from expression pattern /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0021506 // anterior neuropore closure // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021623 // oculomotor nerve formation // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from electronic annotation /// 0070172 // positive regulation of tooth mineralization // inferred from direct assay /// 0071281 // cellular response to iron ion // inferred from direct assay /// 0071711 // basement membrane organization // inferred from electronic annotation /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 204655_at NM_002985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002985.1 /DEF=Homo sapiens small inducible cytokine A5 (RANTES) (SCYA5), mRNA. /FEA=mRNA /GEN=SCYA5 /PROD=small inducible cytokine A5 (RANTES) /DB_XREF=gi:4506846 /UG=Hs.241392 small inducible cytokine A5 (RANTES) /FL=gb:AF043341.1 gb:M21121.1 gb:NM_002985.1 gb:AF266753.1 NM_002985 chemokine (C-C motif) ligand 5 CCL5 6352 NM_001278736 /// NM_002985 0000165 // MAPK cascade // inferred from mutant phenotype /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002676 // regulation of chronic inflammatory response // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // non-traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // traceable author statement /// 0010759 // positive regulation of macrophage chemotaxis // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031328 // positive regulation of cellular biosynthetic process // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045070 // positive regulation of viral genome replication // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045089 // positive regulation of innate immune response // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045948 // positive regulation of translational initiation // non-traceable author statement /// 0046427 // positive regulation of JAK-STAT cascade // traceable author statement /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from direct assay /// 0070234 // positive regulation of T cell apoptotic process // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 2000110 // negative regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000406 // positive regulation of T cell migration // inferred from direct assay /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // non-traceable author statement /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0030298 // receptor signaling protein tyrosine kinase activator activity // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031726 // CCR1 chemokine receptor binding // traceable author statement /// 0031729 // CCR4 chemokine receptor binding // traceable author statement /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0046817 // chemokine receptor antagonist activity // inferred from direct assay 204656_at AL138752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL138752 /DEF=Human DNA sequence from clone RP11-3J10 on chromosome 9p12-13.3 Contains part of a novel gene, the 3 end of the SHB (SHB adaptor protein (a Src homology 2 ) protein ) gene, the gene for CG7943 protein, a pseudogene similar to CGI-31 protein, a ps... /FEA=mRNA_2 /DB_XREF=gi:8452480 /UG=Hs.244542 SHB adaptor protein (a Src homology 2 protein) /FL=gb:NM_003028.1 AL138752 Src homology 2 domain containing adaptor protein B SHB 6461 NM_003028 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 1900194 // negative regulation of oocyte maturation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204657_s_at NM_003028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003028.1 /DEF=Homo sapiens SHB adaptor protein (a Src homology 2 protein) (SHB), mRNA. /FEA=mRNA /GEN=SHB /PROD=SHB adaptor protein (a Src homology 2 protein) /DB_XREF=gi:4506934 /UG=Hs.244542 SHB adaptor protein (a Src homology 2 protein) /FL=gb:NM_003028.1 NM_003028 Src homology 2 domain containing adaptor protein B SHB 6461 NM_003028 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 1900194 // negative regulation of oocyte maturation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204658_at NM_013293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013293.1 /DEF=Homo sapiens transformer-2 alpha (htra-2 alpha) (HSU53209), mRNA. /FEA=mRNA /GEN=HSU53209 /PROD=transformer-2 alpha (htra-2 alpha) /DB_XREF=gi:9558732 /UG=Hs.24937 transformer-2 alpha (htra-2 alpha) /FL=gb:U53209.1 gb:NM_013293.1 NM_013293 transformer 2 alpha homolog (Drosophila) TRA2A 29896 NM_001282757 /// NM_001282758 /// NM_001282759 /// NM_013293 /// XM_005249725 /// XM_006715713 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204659_s_at AF124604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF124604.1 /DEF=Homo sapiens hepatopoietin HPO2 mRNA, complete cds. /FEA=mRNA /PROD=hepatopoietin HPO2 /DB_XREF=gi:4325313 /UG=Hs.27184 growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) /FL=gb:AF306863.1 gb:AF208342.1 gb:AF124604.1 gb:NM_005262.1 gb:U31176.1 AF124604 growth factor, augmenter of liver regeneration GFER 2671 NM_005262 0006626 // protein targeting to mitochondrion // traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016972 // thiol oxidase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 204660_at NM_005262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005262.1 /DEF=Homo sapiens growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) (GFER), mRNA. /FEA=mRNA /GEN=GFER /PROD=erv1-like growth factor /DB_XREF=gi:4885264 /UG=Hs.27184 growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) /FL=gb:AF306863.1 gb:AF208342.1 gb:AF124604.1 gb:NM_005262.1 gb:U31176.1 NM_005262 growth factor, augmenter of liver regeneration GFER 2671 NM_005262 0006626 // protein targeting to mitochondrion // traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016972 // thiol oxidase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 204661_at NM_001803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001803.1 /DEF=Homo sapiens CDW52 antigen (CAMPATH-1 antigen) (CDW52), mRNA. /FEA=mRNA /GEN=CDW52 /PROD=CDW52 antigen (CAMPATH-1 antigen) /DB_XREF=gi:4502760 /UG=Hs.276770 CDW52 antigen (CAMPATH-1 antigen) /FL=gb:BC000644.1 gb:NM_001803.1 NM_001803 CD52 molecule CD52 1043 NM_001803 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0045730 // respiratory burst // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 204662_at NM_014711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014711.1 /DEF=Homo sapiens KIAA0419 gene product (KIAA0419), mRNA. /FEA=mRNA /GEN=KIAA0419 /PROD=KIAA0419 gene product /DB_XREF=gi:7662105 /UG=Hs.279912 KIAA0419 gene product /FL=gb:AB007879.1 gb:NM_014711.1 NM_014711 centriolar coiled coil protein 110kDa CCP110 9738 NM_001199022 /// NM_014711 /// XM_005255719 /// XM_005255721 /// XM_006721105 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0051298 // centrosome duplication // inferred from direct assay /// 0051298 // centrosome duplication // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204663_at NM_006680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006680.1 /DEF=Homo sapiens malic enzyme 3, NADP(+)-dependent, mitochondrial (ME3), mRNA. /FEA=mRNA /GEN=ME3 /PROD=malic enzyme 3, NADP(+)-dependent,mitochondrial /DB_XREF=gi:5729919 /UG=Hs.2838 malic enzyme 3, NADP(+)-dependent, mitochondrial /FL=gb:NM_006680.1 NM_006680 malic enzyme 3, NADP(+)-dependent, mitochondrial ME3 10873 NM_001014811 /// NM_001161586 /// NM_006680 /// XM_005273717 /// XM_006718423 /// XR_247183 0006090 // pyruvate metabolic process // inferred from direct assay /// 0006108 // malate metabolic process // inferred from direct assay /// 0009060 // aerobic respiration // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0072592 // oxygen metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // traceable author statement /// 0051287 // NAD binding // inferred from electronic annotation 204664_at NM_001632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001632.2 /DEF=Homo sapiens alkaline phosphatase, placental (Regan isozyme) (ALPP), mRNA. /FEA=mRNA /GEN=ALPP /PROD=placental alkaline phosphatase precursor /DB_XREF=gi:13787194 /UG=Hs.284255 alkaline phosphatase, placental (Regan isozyme) /FL=gb:NM_001632.2 gb:M12551.1 NM_001632 alkaline phosphatase, placental ALPP 250 NM_001632 /// XM_005246439 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // inferred from direct assay /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204665_at NM_025073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_025073.1 /DEF=Homo sapiens hypothetical protein FLJ21168 (FLJ21168), mRNA. /FEA=mRNA /GEN=FLJ21168 /PROD=hypothetical protein FLJ21168 /DB_XREF=gi:13376618 /UG=Hs.288106 hypothetical protein FLJ21168 /FL=gb:NM_025073.1 NM_025073 suppressor of IKBKE 1 SIKE1 80143 NM_001102396 /// NM_025073 /// NR_049741 /// NR_049742 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 204666_s_at NM_025073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025073.1 /DEF=Homo sapiens hypothetical protein FLJ21168 (FLJ21168), mRNA. /FEA=mRNA /GEN=FLJ21168 /PROD=hypothetical protein FLJ21168 /DB_XREF=gi:13376618 /UG=Hs.288106 hypothetical protein FLJ21168 /FL=gb:NM_025073.1 NM_025073 suppressor of IKBKE 1 SIKE1 80143 NM_001102396 /// NM_025073 /// NR_049741 /// NR_049742 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204667_at NM_004496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004496.1 /DEF=Homo sapiens hepatocyte nuclear factor 3, alpha (HNF3A), mRNA. /FEA=mRNA /GEN=HNF3A /PROD=hepatocyte nuclear factor 3, alpha /DB_XREF=gi:4758533 /UG=Hs.299867 hepatocyte nuclear factor 3, alpha /FL=gb:U39840.1 gb:NM_004496.1 NM_004496 forkhead box A1 FOXA1 3169 NM_004496 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0006338 // chromatin remodeling // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048665 // neuron fate specification // not recorded /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // not recorded /// 0060738 // epithelial-mesenchymal signaling involved in prostate gland development // not recorded /// 0060740 // prostate gland epithelium morphogenesis // not recorded /// 0060741 // prostate gland stromal morphogenesis // not recorded /// 0060743 // epithelial cell maturation involved in prostate gland development // not recorded /// 0061448 // connective tissue development // inferred from electronic annotation /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 204668_at AL031670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031670 /DEF=Human DNA sequence from clone RP4-681N20 on chromosome 20p12.1-13 Contains a gene similar to FTLL1(ferritin, light polypeptide-like 1), a gene similar to Zinc finger, C3HC4 type (RING finger), weakly similar to SW:GOLI_DROME Q06003 GOLIATH PROTEIN... /FEA=mRNA_2 /DB_XREF=gi:4469083 /UG=Hs.30524 ring finger protein 24 /FL=gb:NM_007219.2 gb:AF151081.1 AL031670 ring finger protein 24 RNF24 11237 NM_001134337 /// NM_001134338 /// NM_007219 /// XM_006723536 /// XM_006723537 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204669_s_at NM_007219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007219.2 /DEF=Homo sapiens ring finger protein 24 (RNF24), mRNA. /FEA=mRNA /GEN=RNF24 /PROD=ring finger protein 24 /DB_XREF=gi:10518498 /UG=Hs.30524 ring finger protein 24 /FL=gb:NM_007219.2 gb:AF151081.1 NM_007219 ring finger protein 24 RNF24 11237 NM_001134337 /// NM_001134338 /// NM_007219 /// XM_006723536 /// XM_006723537 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204670_x_at NM_002125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002125.1 /DEF=Homo sapiens major histocompatibility complex, class II, DR beta 5 (HLA-DRB5), mRNA. /FEA=mRNA /GEN=HLA-DRB5 /PROD=major histocompatibility complex, class II, DRbeta 5 /DB_XREF=gi:4504412 /UG=Hs.308026 major histocompatibility complex, class II, DR beta 5 /FL=gb:M11867.1 gb:M20430.1 gb:NM_002125.1 NM_002125 major histocompatibility complex, class II, DR beta 1 /// major histocompatibility complex, class II, DR beta 4 /// HLA class II histocompatibility antigen, DRB1-10 beta chain-like HLA-DRB1 /// HLA-DRB4 /// LOC100996809 3123 /// 3126 /// 100996809 NM_001243965 /// NM_002124 /// NM_021983 /// XM_006710174 /// XM_006710243 /// XM_006725752 /// XM_006725860 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 /// XR_430944 /// XR_430980 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 204671_s_at BE677131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE677131 /FEA=EST /DB_XREF=gi:10037672 /DB_XREF=est:7d80g06.x1 /CLONE=IMAGE:3279322 /UG=Hs.30991 KIAA0957 protein /FL=gb:AB023174.1 gb:NM_014942.1 BE677131 ankyrin repeat domain 6 ANKRD6 22881 NM_001242809 /// NM_001242811 /// NM_001242813 /// NM_001242814 /// NM_014942 /// XM_005248679 /// XM_005248680 /// XM_005248681 /// XM_005248682 /// XM_005248683 /// XM_005248684 /// XM_006715381 /// XM_006715382 0046330 // positive regulation of JNK cascade // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // not recorded /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0005515 // protein binding // inferred from electronic annotation 204672_s_at NM_014942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014942.1 /DEF=Homo sapiens KIAA0957 protein (KIAA0957), mRNA. /FEA=mRNA /GEN=KIAA0957 /PROD=KIAA0957 protein /DB_XREF=gi:7662405 /UG=Hs.30991 KIAA0957 protein /FL=gb:AB023174.1 gb:NM_014942.1 NM_014942 ankyrin repeat domain 6 ANKRD6 22881 NM_001242809 /// NM_001242811 /// NM_001242813 /// NM_001242814 /// NM_014942 /// XM_005248679 /// XM_005248680 /// XM_005248681 /// XM_005248682 /// XM_005248683 /// XM_005248684 /// XM_006715381 /// XM_006715382 0046330 // positive regulation of JNK cascade // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // not recorded /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0005515 // protein binding // inferred from electronic annotation 204673_at NM_002457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002457.1 /DEF=Homo sapiens mucin 2, intestinaltracheal (MUC2), mRNA. /FEA=mRNA /GEN=MUC2 /PROD=mucin 2, intestinaltracheal /DB_XREF=gi:4505284 /UG=Hs.315 mucin 2, intestinaltracheal /FL=gb:NM_002457.1 gb:L21998.1 NM_002457 mucin 2, oligomeric mucus/gel-forming MUC2 4583 NM_002457 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0070701 // mucus layer // inferred from electronic annotation /// 0070702 // inner mucus layer // inferred from sequence or structural similarity /// 0070703 // outer mucus layer // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204674_at NM_006152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006152.1 /DEF=Homo sapiens lymphoid-restricted membrane protein (LRMP), mRNA. /FEA=mRNA /GEN=LRMP /PROD=lymphoid-restricted membrane protein /DB_XREF=gi:5453723 /UG=Hs.40202 lymphoid-restricted membrane protein /FL=gb:U10485.1 gb:NM_006152.1 NM_006152 lymphoid-restricted membrane protein LRMP 4033 NM_001204126 /// NM_001204127 /// NM_006152 /// XM_005253370 /// XM_005253371 /// XM_005253372 /// XM_005253374 /// XM_006719075 /// XM_006719076 /// XM_006719077 /// XR_242890 /// XR_429033 0002376 // immune system process // inferred from electronic annotation /// 0006903 // vesicle targeting // traceable author statement /// 0006906 // vesicle fusion // traceable author statement /// 0007338 // single fertilization // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 204675_at NM_001047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001047.1 /DEF=Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1), mRNA. /FEA=mRNA /GEN=SRD5A1 /PROD=steroid-5-alpha-reductase, alpha polypeptide 1(3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) /DB_XREF=gi:4507200 /UG=Hs.552 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) /FL=gb:M32313.1 gb:AF052126.1 gb:NM_001047.1 NM_001047 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) SRD5A1 6715 NM_001047 /// XR_427663 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0007530 // sex determination // non-traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003865 // 3-oxo-5-alpha-steroid 4-dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0047751 // cholestenone 5-alpha-reductase activity // inferred from electronic annotation 204676_at NM_015421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015421.1 /DEF=Homo sapiens DKFZP564K2062 protein (DKFZP564K2062), mRNA. /FEA=mRNA /GEN=DKFZP564K2062 /PROD=DKFZP564K2062 protein /DB_XREF=gi:7661617 /UG=Hs.70877 DKFZP564K2062 protein /FL=gb:AL080088.1 gb:NM_015421.1 NM_015421 transmembrane protein 186 TMEM186 25880 NM_015421 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204677_at NM_001795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001795.1 /DEF=Homo sapiens cadherin 5, type 2, VE-cadherin (vascular epithelium) (CDH5), mRNA. /FEA=mRNA /GEN=CDH5 /PROD=cadherin 5, type 2, VE-cadherin (vascularepithelium) /DB_XREF=gi:4502726 /UG=Hs.76206 cadherin 5, type 2, VE-cadherin (vascular epithelium) /FL=gb:U84722.1 gb:NM_001795.1 gb:AB035304.1 NM_001795 cadherin 5, type 2 (vascular endothelium) CDH5 1003 NM_001114117 /// NM_001795 0001955 // blood vessel maturation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0071944 // cell periphery // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204678_s_at U90065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90065.1 /DEF=Human potassium channel KCNO1 mRNA, complete cds. /FEA=mRNA /PROD=potassium channel KCNO1 /DB_XREF=gi:1916294 /UG=Hs.79351 potassium channel, subfamily K, member 1 (TWIK-1) /FL=gb:U33632.1 gb:U90065.1 gb:U76996.1 gb:NM_002245.1 U90065 potassium channel, subfamily K, member 1 KCNK1 3775 NM_002245 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 204679_at NM_002245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002245.1 /DEF=Homo sapiens potassium channel, subfamily K, member 1 (TWIK-1) (KCNK1), mRNA. /FEA=mRNA /GEN=KCNK1 /PROD=potassium channel, subfamily K, member 1(TWIK-1) /DB_XREF=gi:4504846 /UG=Hs.79351 potassium channel, subfamily K, member 1 (TWIK-1) /FL=gb:U33632.1 gb:U90065.1 gb:U76996.1 gb:NM_002245.1 NM_002245 potassium channel, subfamily K, member 1 KCNK1 3775 NM_002245 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 204680_s_at AI263837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI263837 /FEA=EST /DB_XREF=gi:3872040 /DB_XREF=est:qi10g07.x1 /CLONE=IMAGE:1856124 /UG=Hs.80620 guanine nucleotide exchange factor for Rap1; M-Ras-regulated GEF /FL=gb:D87467.1 gb:NM_012294.1 AI263837 Rap guanine nucleotide exchange factor (GEF) 5 RAPGEF5 9771 NM_012294 /// XM_005249914 /// XM_005249915 /// XM_005249916 /// XM_005249917 /// XM_006715804 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0032317 // regulation of Rap GTPase activity // inferred from direct assay /// 0032318 // regulation of Ras GTPase activity // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 204681_s_at NM_012294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012294.1 /DEF=Homo sapiens guanine nucleotide exchange factor for Rap1; M-Ras-regulated GEF (KIAA0277), mRNA. /FEA=mRNA /GEN=KIAA0277 /PROD=guanine nucleotide exchange factor for Rap1;M-Ras-regulated GEF /DB_XREF=gi:6912455 /UG=Hs.80620 guanine nucleotide exchange factor for Rap1; M-Ras-regulated GEF /FL=gb:D87467.1 gb:NM_012294.1 NM_012294 Rap guanine nucleotide exchange factor (GEF) 5 RAPGEF5 9771 NM_012294 /// XM_005249914 /// XM_005249915 /// XM_005249916 /// XM_005249917 /// XM_006715804 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0032317 // regulation of Rap GTPase activity // inferred from direct assay /// 0032318 // regulation of Ras GTPase activity // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 204682_at NM_000428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000428.1 /DEF=Homo sapiens latent transforming growth factor beta binding protein 2 (LTBP2), mRNA. /FEA=mRNA /GEN=LTBP2 /PROD=latent transforming growth factor beta bindingprotein 2 /DB_XREF=gi:4557732 /UG=Hs.83337 latent transforming growth factor beta binding protein 2 /FL=gb:NM_000428.1 NM_000428 latent transforming growth factor beta binding protein 2 LTBP2 4053 NM_000428 0006605 // protein targeting // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0009306 // protein secretion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 204683_at NM_000873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000873.2 /DEF=Homo sapiens intercellular adhesion molecule 2 (ICAM2), mRNA. /FEA=mRNA /GEN=ICAM2 /PROD=intercellular adhesion molecule 2 precursor /DB_XREF=gi:12545398 /UG=Hs.83733 intercellular adhesion molecule 2 /FL=gb:NM_000873.2 gb:BC003097.1 NM_000873 intercellular adhesion molecule 2 ICAM2 3384 NM_000873 /// NM_001099786 /// NM_001099787 /// NM_001099788 /// NM_001099789 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0001931 // uropod // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005178 // integrin binding // inferred from physical interaction 204684_at NM_002522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002522.1 /DEF=Homo sapiens neuronal pentraxin I (NPTX1), mRNA. /FEA=mRNA /GEN=NPTX1 /PROD=neuronal pentraxin I precursor /DB_XREF=gi:4505442 /UG=Hs.84154 neuronal pentraxin I /FL=gb:U61849.1 gb:NM_002522.1 NM_002522 neuronal pentraxin I NPTX1 4884 NM_002522 0006810 // transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0035865 // cellular response to potassium ion // inferred from electronic annotation /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from electronic annotation /// 0060385 // axonogenesis involved in innervation // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 204685_s_at R52647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R52647 /FEA=EST /DB_XREF=gi:814549 /DB_XREF=est:yg82f05.s1 /CLONE=IMAGE:39910 /UG=Hs.89512 ATPase, Ca++ transporting, plasma membrane 2 /FL=gb:L20977.1 gb:NM_001683.1 R52647 ATPase, Ca++ transporting, plasma membrane 2 ATP2B2 491 NM_001001331 /// NM_001683 /// XM_005265179 /// XM_006713175 /// XM_006713176 /// XM_006713177 /// XM_006713178 /// XM_006713179 /// XM_006713180 /// XM_006713181 /// XM_006713182 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006996 // organelle organization // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021692 // cerebellar Purkinje cell layer morphogenesis // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0040011 // locomotion // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045299 // otolith mineralization // inferred from electronic annotation /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030899 // calcium-dependent ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204686_at NM_005544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005544.1 /DEF=Homo sapiens insulin receptor substrate 1 (IRS1), mRNA. /FEA=mRNA /GEN=IRS1 /PROD=insulin receptor substrate 1 /DB_XREF=gi:5031804 /UG=Hs.96063 insulin receptor substrate 1 /FL=gb:NM_005544.1 NM_005544 insulin receptor substrate 1 IRS1 3667 NM_005544 /// XM_005246534 /// XM_006712512 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032868 // response to insulin // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005899 // insulin receptor complex // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity 204687_at NM_015393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015393.1 /DEF=Homo sapiens DKFZP564O0823 protein (DKFZP564O0823), mRNA. /FEA=mRNA /GEN=DKFZP564O0823 /PROD=DKFZP564O0823 protein /DB_XREF=gi:7661631 /UG=Hs.105460 DKFZP564O0823 protein /FL=gb:AL080121.1 gb:NM_015393.1 NM_015393 prostate androgen-regulated mucin-like protein 1 PARM1 25849 NM_015393 0051973 // positive regulation of telomerase activity // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 204688_at NM_003919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003919.1 /DEF=Homo sapiens sarcoglycan, epsilon (SGCE), mRNA. /FEA=mRNA /GEN=SGCE /PROD=sarcoglycan, epsilon /DB_XREF=gi:10835046 /UG=Hs.110708 sarcoglycan, epsilon /FL=gb:NM_003919.1 gb:AF036364.1 NM_003919 sarcoglycan, epsilon SGCE 8910 NM_001099400 /// NM_001099401 /// NM_003919 /// XM_005250675 /// XM_005250677 /// XM_005250679 /// XM_006716165 /// XM_006716166 /// XM_006716167 /// XR_428187 0007160 // cell-matrix adhesion // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 204689_at NM_001529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001529.1 /DEF=Homo sapiens hematopoietically expressed homeobox (HHEX), mRNA. /FEA=mRNA /GEN=HHEX /PROD=hematopoietically expressed homeobox /DB_XREF=gi:10835016 /UG=Hs.118651 hematopoietically expressed homeobox /FL=gb:NM_001529.1 gb:L16499.1 gb:NM_002729.1 NM_001529 hematopoietically expressed homeobox HHEX 3087 NM_002729 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010621 // negative regulation of transcription by transcription factor localization // inferred by curator /// 0010944 // negative regulation of transcription by competitive promoter binding // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred by curator /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0031016 // pancreas development // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0060431 // primary lung bud formation // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061010 // gall bladder development // inferred from electronic annotation /// 0061011 // hepatic duct development // inferred from electronic annotation /// 0061017 // hepatoblast differentiation // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0071103 // DNA conformation change // inferred from direct assay /// 0090009 // primitive streak formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0017025 // TBP-class protein binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // traceable author statement /// 0070491 // repressing transcription factor binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 204690_at NM_004853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004853.1 /DEF=Homo sapiens syntaxin 8 (STX8), mRNA. /FEA=mRNA /GEN=STX8 /PROD=syntaxin 8 /DB_XREF=gi:4759187 /UG=Hs.119525 syntaxin 8 /FL=gb:AF062077.1 gb:AF036715.1 gb:AF115323.1 gb:NM_004853.1 NM_004853 syntaxin 8 STX8 9482 NM_004853 /// NR_033656 0006810 // transport // traceable author statement /// 0006886 // intracellular protein transport // not recorded /// 0006906 // vesicle fusion // not recorded /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031902 // late endosome membrane // inferred from electronic annotation 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 204691_x_at NM_003560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003560.1 /DEF=Homo sapiens phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), mRNA. /FEA=mRNA /GEN=PLA2G6 /PROD=phospholipase A2, group VI (cytosolic,calcium-independent) /DB_XREF=gi:6981363 /UG=Hs.120360 phospholipase A2, group VI (cytosolic, calcium-independent) /FL=gb:AF064594.1 gb:AF102989.1 gb:NM_003560.1 NM_003560 phospholipase A2, group VI (cytosolic, calcium-independent) PLA2G6 8398 NM_001004426 /// NM_001199562 /// NM_003560 /// XM_005261764 /// XM_005261765 /// XM_005261766 /// XM_005261771 /// XM_006724332 /// XR_244390 /// XR_244392 /// XR_430411 /// XR_430412 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090238 // positive regulation of arachidonic acid secretion // inferred from electronic annotation /// 1901339 // regulation of store-operated calcium channel activity // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from electronic annotation 204692_at NM_002319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002319.1 /DEF=Homo sapiens leucine-rich neuronal protein (LRN), mRNA. /FEA=mRNA /GEN=LRN /PROD=leucine-rich neuronal protein /DB_XREF=gi:4505012 /UG=Hs.125742 leucine-rich neuronal protein /FL=gb:NM_002319.1 NM_002319 leucine-rich repeats and calponin homology (CH) domain containing 4 /// Sin3A-associated protein, 25kDa LRCH4 /// SAP25 4034 /// 100316904 NM_001168682 /// NM_001289934 /// NM_002319 /// XM_005250096 /// XM_005250346 /// XM_005250347 /// XM_006715822 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204693_at NM_007061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007061.1 /DEF=Homo sapiens serum constituent protein (MSE55), mRNA. /FEA=mRNA /GEN=MSE55 /PROD=serum constituent protein /DB_XREF=gi:5902007 /UG=Hs.148101 serum constituent protein /FL=gb:M88338.1 gb:NM_007061.1 NM_007061 CDC42 effector protein (Rho GTPase binding) 1 CDC42EP1 11135 NM_152243 /// XM_006724107 /// XM_006724108 /// XM_006724109 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204694_at NM_001134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001134.1 /DEF=Homo sapiens alpha-fetoprotein (AFP), mRNA. /FEA=mRNA /GEN=AFP /PROD=alpha-fetoprotein /DB_XREF=gi:4501988 /UG=Hs.155421 alpha-fetoprotein /FL=gb:J00077.1 gb:NM_001134.1 NM_001134 alpha-fetoprotein AFP 174 NM_001134 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0042448 // progesterone metabolic process // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 204695_at AI343459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI343459 /FEA=EST /DB_XREF=gi:4080665 /DB_XREF=est:tb96f05.x1 /CLONE=IMAGE:2062209 /UG=Hs.1634 cell division cycle 25A /FL=gb:M81933.1 gb:NM_001789.1 AI343459 cell division cycle 25A CDC25A 993 NM_001789 /// NM_201567 /// XM_006713434 /// XM_006713435 /// XM_006713436 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 204696_s_at NM_001789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001789.1 /DEF=Homo sapiens cell division cycle 25A (CDC25A), mRNA. /FEA=mRNA /GEN=CDC25A /PROD=cell division cycle 25A /DB_XREF=gi:4502704 /UG=Hs.1634 cell division cycle 25A /FL=gb:M81933.1 gb:NM_001789.1 NM_001789 cell division cycle 25A CDC25A 993 NM_001789 /// NM_201567 /// XM_006713434 /// XM_006713435 /// XM_006713436 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 204697_s_at NM_001275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001275.2 /DEF=Homo sapiens chromogranin A (parathyroid secretory protein 1) (CHGA), mRNA. /FEA=mRNA /GEN=CHGA /PROD=chromogranin A /DB_XREF=gi:10800418 /UG=Hs.172216 chromogranin A (parathyroid secretory protein 1) /FL=gb:NM_001275.2 gb:BC001059.1 gb:J03483.1 gb:J03915.1 NM_001275 chromogranin A (parathyroid secretory protein 1) CHGA 1113 NM_001275 /// XM_005267292 /// XM_006725160 0008217 // regulation of blood pressure // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 204698_at NM_002201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002201.2 /DEF=Homo sapiens interferon stimulated gene (20kD) (ISG20), mRNA. /FEA=mRNA /GEN=ISG20 /PROD=interferon stimulated gene (20kD) /DB_XREF=gi:6857799 /UG=Hs.183487 interferon stimulated gene (20kD) /FL=gb:U88964.1 gb:NM_002201.2 NM_002201 interferon stimulated exonuclease gene 20kDa ISG20 3669 NM_002201 /// XM_005254899 /// XM_005254900 /// XM_006720488 /// XM_006720489 /// XM_006720490 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006401 // RNA catabolic process // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from mutant phenotype /// 0008310 // single-stranded DNA 3'-5' exodeoxyribonuclease activity // inferred from direct assay /// 0008859 // exoribonuclease II activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030619 // U1 snRNA binding // inferred from direct assay /// 0030620 // U2 snRNA binding // inferred from direct assay /// 0034511 // U3 snoRNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204699_s_at N30910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N30910 /FEA=EST /DB_XREF=gi:1149430 /DB_XREF=est:yw76h01.s1 /CLONE=IMAGE:258193 /UG=Hs.194754 novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7 /FL=gb:NM_014388.1 N30910 digestive organ expansion factor homolog (zebrafish) DIEXF 27042 NM_014388 /// XM_006711275 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 204700_x_at NM_014388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014388.1 /DEF=Homo sapiens novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7 (DJ434O14.5), mRNA. /FEA=mRNA /GEN=DJ434O14.5 /PROD=novel putative protein similar to YIL091C yeasthypothetical 84 kD protein from SGA1-KTR7 /DB_XREF=gi:7657018 /UG=Hs.194754 novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7 /FL=gb:NM_014388.1 NM_014388 digestive organ expansion factor homolog (zebrafish) DIEXF 27042 NM_014388 /// XM_006711275 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 204701_s_at NM_004809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004809.1 /DEF=Homo sapiens stomatin-like 1 (STOML1), mRNA. /FEA=mRNA /GEN=STOML1 /PROD=stomatin-like 1 /DB_XREF=gi:4759147 /UG=Hs.194816 stomatin (EBP72)-like 1 /FL=gb:NM_004809.1 gb:AF156557.1 NM_004809 stomatin (EPB72)-like 1 STOML1 9399 NM_001256672 /// NM_001256673 /// NM_001256674 /// NM_001256675 /// NM_001256676 /// NM_001256677 /// NM_004809 /// XM_005254792 /// XM_005254793 /// XM_006720771 /// XM_006720772 /// XM_006720773 /// XM_006720774 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032934 // sterol binding // inferred from electronic annotation 204702_s_at NM_004289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004289.3 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 3 (NFE2L3), mRNA. /FEA=mRNA /GEN=NFE2L3 /PROD=nuclear factor (erythroid-derived 2)-like 3 /DB_XREF=gi:5731346 /UG=Hs.22900 nuclear factor (erythroid-derived 2)-like 3 /FL=gb:AF133059.1 gb:AB010812.1 gb:NM_004289.3 gb:AF134891.1 NM_004289 nuclear factor, erythroid 2-like 3 NFE2L3 9603 NM_004289 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204703_at NM_006531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006531.1 /DEF=Homo sapiens Probe hTg737 (polycystic kidney disease, autosomal recessive, in) (TG737), mRNA. /FEA=mRNA /GEN=TG737 /PROD=Tg737 protein /DB_XREF=gi:5729799 /UG=Hs.2291 Probe hTg737 (polycystic kidney disease, autosomal recessive, in) /FL=gb:NM_006531.1 gb:U20362.1 NM_006531 intraflagellar transport 88 homolog (Chlamydomonas) IFT88 8100 NM_006531 /// NM_175605 /// XM_005266546 /// XM_005266547 /// XM_005266548 /// XM_005266549 /// XM_005266550 /// XM_005266551 /// XM_005266552 /// XM_005266553 /// XM_005266555 /// XM_006719869 /// XM_006719870 /// XR_245399 0001654 // eye development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0021513 // spinal cord dorsal/ventral patterning // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060411 // cardiac septum morphogenesis // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity /// 2000785 // regulation of autophagic vacuole assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0005930 // axoneme // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204704_s_at BF195998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195998 /FEA=EST /DB_XREF=gi:11083462 /DB_XREF=est:7o88f07.x1 /CLONE=IMAGE:3643525 /UG=Hs.234234 aldolase B, fructose-bisphosphate /FL=gb:K01177.1 gb:NM_000035.1 BF195998 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 204705_x_at NM_000035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000035.1 /DEF=Homo sapiens aldolase B, fructose-bisphosphate (ALDOB), mRNA. /FEA=mRNA /GEN=ALDOB /PROD=aldolase B, fructose-bisphosphate /DB_XREF=gi:4557306 /UG=Hs.234234 aldolase B, fructose-bisphosphate /FL=gb:K01177.1 gb:NM_000035.1 NM_000035 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 204706_at NM_019892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019892.1 /DEF=Homo sapiens phosphatidylinositol (4,5) bisphosphate 5-phosphatase homolog; phosphatidylinositol polyphosphate 5-phosphatase type IV (PPI5PIV), mRNA. /FEA=mRNA /GEN=PPI5PIV /PROD=phosphatidylinositol polyphosphate 5-phosphatasetype IV /DB_XREF=gi:9845290 /UG=Hs.25156 phosphatidylinositol (4,5) bisphosphate 5-phosphatase homolog; phosphatidylinositol polyphosphate 5-phosphatase type IV /FL=gb:AF187891.1 gb:NM_019892.1 NM_019892 inositol polyphosphate-5-phosphatase, 72 kDa INPP5E 56623 NM_019892 /// XM_005266094 /// XM_006717187 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 204707_s_at BF115223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF115223 /FEA=EST /DB_XREF=gi:10984699 /DB_XREF=est:7n80a11.x1 /CLONE=IMAGE:3570740 /UG=Hs.269222 mitogen-activated protein kinase 4 /FL=gb:NM_002747.2 BF115223 mitogen-activated protein kinase 4 MAPK4 5596 NM_001292039 /// NM_001292040 /// NM_002747 /// XM_005258299 0000165 // MAPK cascade // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204708_at NM_002747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002747.2 /DEF=Homo sapiens mitogen-activated protein kinase 4 (MAPK4), mRNA. /FEA=mRNA /GEN=MAPK4 /PROD=mitogen-activated protein kinase 4 /DB_XREF=gi:6715608 /UG=Hs.269222 mitogen-activated protein kinase 4 /FL=gb:NM_002747.2 NM_002747 mitogen-activated protein kinase 4 MAPK4 5596 NM_001292039 /// NM_001292040 /// NM_002747 /// XM_005258299 0000165 // MAPK cascade // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204709_s_at NM_004856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004856.3 /DEF=Homo sapiens kinesin-like 5 (mitotic kinesin-like protein 1) (KNSL5), mRNA. /FEA=mRNA /GEN=KNSL5 /PROD=kinesin-like 5 /DB_XREF=gi:13699831 /UG=Hs.270845 kinesin-like 5 (mitotic kinesin-like protein 1) /FL=gb:NM_004856.3 NM_004856 kinesin family member 23 KIF23 9493 NM_001281301 /// NM_004856 /// NM_138555 /// XM_005254796 /// XM_005254797 /// XM_005254798 /// XM_005254799 /// XM_006720778 /// XM_006720779 /// XM_006720780 /// XM_006720781 0000022 // mitotic spindle elongation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051256 // spindle midzone assembly involved in mitosis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0045171 // intercellular bridge // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay /// 0097149 // centralspindlin complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay 204710_s_at NM_016003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016003.1 /DEF=Homo sapiens CGI-50 protein (LOC51623), mRNA. /FEA=mRNA /GEN=LOC51623 /PROD=CGI-50 protein /DB_XREF=gi:7706293 /UG=Hs.279850 CGI-50 protein /FL=gb:AF151808.1 gb:NM_016003.1 NM_016003 WD repeat domain, phosphoinositide interacting 2 WIPI2 26100 NM_001033518 /// NM_001033519 /// NM_001033520 /// NM_001278299 /// NM_015610 /// NM_016003 /// XM_006715685 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000421 // autophagic vacuole membrane // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 204711_at NM_014804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014804.1 /DEF=Homo sapiens KIAA0753 gene product (KIAA0753), mRNA. /FEA=mRNA /GEN=KIAA0753 /PROD=KIAA0753 gene product /DB_XREF=gi:7662287 /UG=Hs.28070 KIAA0753 gene product /FL=gb:AB018296.1 gb:NM_014804.1 NM_014804 KIAA0753 KIAA0753 9851 NM_014804 /// XM_005256881 /// XM_005256882 /// XM_005256884 /// XM_005256885 /// XM_006721609 /// XM_006721610 /// XM_006721611 /// XM_006721612 /// XR_429828 /// XR_429829 /// XR_429830 /// XR_429831 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 204712_at NM_007191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007191.1 /DEF=Homo sapiens Wnt inhibitory factor-1 (WIF-1), mRNA. /FEA=mRNA /GEN=WIF-1 /PROD=Wnt inhibitory factor-1 /DB_XREF=gi:6005949 /UG=Hs.284122 Wnt inhibitory factor-1 /FL=gb:AF122922.1 gb:NM_007191.1 NM_007191 WNT inhibitory factor 1 WIF1 11197 NM_007191 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204713_s_at AA910306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA910306 /FEA=EST /DB_XREF=gi:3049596 /DB_XREF=est:ok83a04.s1 /CLONE=IMAGE:1520526 /UG=Hs.30054 coagulation factor V (proaccelerin, labile factor) /FL=gb:NM_000130.2 gb:M16967.1 gb:M14335.1 AA910306 coagulation factor V (proaccelerin, labile factor) F5 2153 NM_000130 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008015 // blood circulation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204714_s_at NM_000130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000130.2 /DEF=Homo sapiens coagulation factor V (proaccelerin, labile factor) (F5), mRNA. /FEA=mRNA /GEN=F5 /PROD=coagulation factor V precursor /DB_XREF=gi:10518500 /UG=Hs.30054 coagulation factor V (proaccelerin, labile factor) /FL=gb:NM_000130.2 gb:M16967.1 gb:M14335.1 NM_000130 coagulation factor V (proaccelerin, labile factor) F5 2153 NM_000130 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008015 // blood circulation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204715_at NM_015368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015368.1 /DEF=Homo sapiens pannexin 1 (PANX1), mRNA. /FEA=mRNA /GEN=PANX1 /PROD=pannexin 1 /DB_XREF=gi:7662507 /UG=Hs.30985 pannexin 1 /FL=gb:AF093239.1 gb:NM_015368.1 NM_015368 pannexin 1 PANX1 24145 NM_015368 /// XM_005273863 0002931 // response to ischemia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0033198 // response to ATP // inferred from electronic annotation /// 0034214 // protein hexamerization // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005921 // gap junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032059 // bleb // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005243 // gap junction channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from electronic annotation /// 0022840 // leak channel activity // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation /// 0055077 // gap junction hemi-channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from electronic annotation 204716_at NM_005436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005436.1 /DEF=Homo sapiens DNA segment, single copy, probe pH4 (transforming sequence, thyroid-1, (D10S170), mRNA. /FEA=mRNA /GEN=D10S170 /PROD=DNA segment, single copy, probe pH4(transforming sequence, thyroid-1, /DB_XREF=gi:4885172 /UG=Hs.315591 DNA segment, single copy, probe pH4 (transforming sequence, thyroid-1, /FL=gb:NM_005436.1 NM_005436 coiled-coil domain containing 6 CCDC6 8030 NM_005436 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 204717_s_at AF034102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF034102.1 /DEF=Homo sapiens NBMPR-insensitive nucleoside transporter ei (ENT2) mRNA, complete cds. /FEA=mRNA /GEN=ENT2 /PROD=NBMPR-insensitive nucleoside transporter ei /DB_XREF=gi:2811136 /UG=Hs.32951 solute carrier family 29 (nucleoside transporters), member 2 /FL=gb:NM_001532.1 gb:AF029358.1 gb:AF034102.1 AF034102 solute carrier family 29 (equilibrative nucleoside transporter), member 2 SLC29A2 3177 NM_001532 /// XM_006718523 /// XM_006718524 /// XM_006718525 /// XM_006718526 /// XM_006718527 /// XM_006718528 /// XR_428912 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0015858 // nucleoside transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 204718_at NM_004445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004445.1 /DEF=Homo sapiens EphB6 (EPHB6) mRNA. /FEA=mRNA /GEN=EPHB6 /PROD=EphB6 /DB_XREF=gi:4758291 /UG=Hs.3796 EphB6 /FL=gb:D83492.1 gb:NM_004445.1 NM_004445 EPH receptor B6 EPHB6 2051 NM_001280794 /// NM_001280795 /// NM_004445 /// NR_104001 /// XM_006715881 /// XM_006715882 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0035898 // parathyroid hormone secretion // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204719_at NM_007168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007168.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 8 (ABCA8), mRNA. /FEA=mRNA /GEN=ABCA8 /PROD=ATP-binding cassette, sub-family A member 8 /DB_XREF=gi:6005700 /UG=Hs.38095 ATP-binding cassette, sub-family A (ABC1), member 8 /FL=gb:AB020629.1 gb:NM_007168.1 NM_007168 ATP-binding cassette, sub-family A (ABC1), member 8 ABCA8 10351 NM_001288985 /// NM_001288986 /// NM_007168 /// XM_005256938 /// XM_005256940 /// XR_243626 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from direct assay 204720_s_at AV729634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV729634 /FEA=EST /DB_XREF=gi:10839055 /DB_XREF=est:AV729634 /CLONE=HTEAFB10 /UG=Hs.44896 DnaJ (Hsp40) homolog, subfamily B, member 6 /FL=gb:AB007942.1 gb:NM_014787.1 AV729634 DnaJ (Hsp40) homolog, subfamily C, member 6 DNAJC6 9829 NM_001256864 /// NM_001256865 /// NM_014787 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 204721_s_at NM_014787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014787.1 /DEF=Homo sapiens KIAA0473 gene product (KIAA0473), mRNA. /FEA=mRNA /GEN=KIAA0473 /PROD=KIAA0473 gene product /DB_XREF=gi:7662145 /UG=Hs.44896 DnaJ (Hsp40) homolog, subfamily B, member 6 /FL=gb:AB007942.1 gb:NM_014787.1 NM_014787 DnaJ (Hsp40) homolog, subfamily C, member 6 DNAJC6 9829 NM_001256864 /// NM_001256865 /// NM_014787 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 204722_at AW007335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007335 /FEA=EST /DB_XREF=gi:5856113 /DB_XREF=est:ws51c06.x1 /CLONE=IMAGE:2500714 /UG=Hs.4865 voltage-gated sodium channel beta-3 subunit (scn3b gene) /FL=gb:AL136589.1 gb:NM_018400.1 AW007335 sodium channel, voltage-gated, type III, beta subunit SCN3B 55800 NM_001040151 /// NM_018400 /// XM_006718882 /// XR_428980 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010460 // positive regulation of heart rate // inferred from sequence or structural similarity /// 0010765 // positive regulation of sodium ion transport // inferred from direct assay /// 0010765 // positive regulation of sodium ion transport // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0051899 // membrane depolarization // inferred from direct assay /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0086010 // membrane depolarization during action potential // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from sequence or structural similarity /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from mutant phenotype 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0001518 // voltage-gated sodium channel complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // non-traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from physical interaction /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from direct assay /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype 204723_at AB032984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032984.1 /DEF=Homo sapiens mRNA for KIAA1158 protein, partial cds. /FEA=mRNA /GEN=KIAA1158 /PROD=KIAA1158 protein /DB_XREF=gi:6330135 /UG=Hs.4865 voltage-gated sodium channel beta-3 subunit (scn3b gene) /FL=gb:AL136589.1 gb:NM_018400.1 AB032984 sodium channel, voltage-gated, type III, beta subunit SCN3B 55800 NM_001040151 /// NM_018400 /// XM_006718882 /// XR_428980 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010460 // positive regulation of heart rate // inferred from sequence or structural similarity /// 0010765 // positive regulation of sodium ion transport // inferred from direct assay /// 0010765 // positive regulation of sodium ion transport // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0051899 // membrane depolarization // inferred from direct assay /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0086010 // membrane depolarization during action potential // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from sequence or structural similarity /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from mutant phenotype 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0001518 // voltage-gated sodium channel complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // non-traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from physical interaction /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from direct assay /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype 204724_s_at NM_001853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001853.1 /DEF=Homo sapiens collagen, type IX, alpha 3 (COL9A3), mRNA. /FEA=mRNA /GEN=COL9A3 /PROD=collagen, type IX, alpha 3 /DB_XREF=gi:4502966 /UG=Hs.53563 collagen, type IX, alpha 3 /FL=gb:L41162.1 gb:NM_001853.1 NM_001853 collagen, type IX, alpha 3 COL9A3 1299 NM_001853 0007411 // axon guidance // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005594 // collagen type IX trimer // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0030020 // extracellular matrix structural constituent conferring tensile strength // inferred by curator 204725_s_at NM_006153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006153.1 /DEF=Homo sapiens NCK adaptor protein 1 (NCK1), mRNA. /FEA=mRNA /GEN=NCK1 /PROD=NCK adaptor protein 1 /DB_XREF=gi:5453753 /UG=Hs.54589 NCK adaptor protein 1 /FL=gb:NM_006153.1 NM_006153 NCK adaptor protein 1 NCK1 4690 NM_001190796 /// NM_001291999 /// NM_006153 /// XM_005247498 /// XM_006713650 /// XM_006713651 /// XM_006713652 0006417 // regulation of translation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007172 // signal complex assembly // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042110 // T cell activation // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051707 // response to other organism // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019887 // protein kinase regulator activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 204726_at NM_001257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001257.1 /DEF=Homo sapiens cadherin 13, H-cadherin (heart) (CDH13), mRNA. /FEA=mRNA /GEN=CDH13 /PROD=cadherin 13, H-cadherin (heart) /DB_XREF=gi:4502718 /UG=Hs.63984 cadherin 13, H-cadherin (heart) /FL=gb:U59288.1 gb:U59289.1 gb:NM_001257.1 gb:L34058.1 NM_001257 cadherin 13 CDH13 1012 NM_001220488 /// NM_001220489 /// NM_001220490 /// NM_001220491 /// NM_001220492 /// NM_001257 /// XM_006721120 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from direct assay /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from direct assay /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from direct assay /// 0043616 // keratinocyte proliferation // inferred from direct assay /// 0045216 // cell-cell junction organization // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0050850 // positive regulation of calcium-mediated signaling // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051668 // localization within membrane // inferred from mutant phenotype /// 0055096 // low-density lipoprotein particle mediated signaling // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055100 // adiponectin binding // inferred from sequence or structural similarity /// 0071813 // lipoprotein particle binding // inferred from direct assay 204727_at AW772140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW772140 /FEA=EST /DB_XREF=gi:7704203 /DB_XREF=est:hn68b03.x1 /CLONE=IMAGE:3033005 /UG=Hs.72160 AND-1 protein /FL=gb:NM_007086.1 AW772140 WD repeat and HMG-box DNA binding protein 1 WDHD1 11169 NM_001008396 /// NM_007086 /// XM_005267294 /// XM_006720012 0006396 // RNA processing // inferred from electronic annotation /// 0033044 // regulation of chromosome organization // inferred from electronic annotation /// 0070829 // heterochromatin maintenance // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0070063 // RNA polymerase binding // inferred from electronic annotation 204728_s_at NM_007086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007086.1 /DEF=Homo sapiens AND-1 protein (AND-1), mRNA. /FEA=mRNA /GEN=AND-1 /PROD=AND-1 protein /DB_XREF=gi:5901891 /UG=Hs.72160 AND-1 protein /FL=gb:NM_007086.1 NM_007086 WD repeat and HMG-box DNA binding protein 1 WDHD1 11169 NM_001008396 /// NM_007086 /// XM_005267294 /// XM_006720012 0006396 // RNA processing // inferred from electronic annotation /// 0033044 // regulation of chromosome organization // inferred from electronic annotation /// 0070829 // heterochromatin maintenance // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0070063 // RNA polymerase binding // inferred from electronic annotation 204729_s_at NM_004603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004603.1 /DEF=Homo sapiens syntaxin 1A (brain) (STX1A), mRNA. /FEA=mRNA /GEN=STX1A /PROD=syntaxin 1A (brain) /DB_XREF=gi:4759181 /UG=Hs.75671 syntaxin 1A (brain) /FL=gb:NM_004603.1 gb:U12918.1 gb:L37792.1 NM_004603 syntaxin 1A (brain) STX1A 6804 NM_001165903 /// NM_004603 /// XM_005250552 /// XR_242263 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009629 // response to gravity // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070033 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0032028 // myosin head/neck binding // inferred from electronic annotation /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation 204730_at NM_014747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014747.1 /DEF=Homo sapiens KIAA0237 gene product (KIAA0237), mRNA. /FEA=mRNA /GEN=KIAA0237 /PROD=KIAA0237 gene product /DB_XREF=gi:7662015 /UG=Hs.78748 KIAA0237 gene product /FL=gb:D87074.1 gb:NM_014747.1 NM_014747 regulating synaptic membrane exocytosis 3 RIMS3 9783 NM_014747 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation 204731_at NM_003243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003243.1 /DEF=Homo sapiens transforming growth factor, beta receptor III (betaglycan, 300kD) (TGFBR3), mRNA. /FEA=mRNA /GEN=TGFBR3 /PROD=transforming growth factor, beta receptor III(betaglycan, 300kD) /DB_XREF=gi:4507470 /UG=Hs.79059 transforming growth factor, beta receptor III (betaglycan, 300kD) /FL=gb:NM_003243.1 gb:L07594.1 NM_003243 transforming growth factor, beta receptor III TGFBR3 7049 NM_001195683 /// NM_001195684 /// NM_003243 /// NR_036634 /// XM_006710867 /// XM_006710868 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001889 // liver development // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007181 // transforming growth factor beta receptor complex assembly // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from electronic annotation /// 0016049 // cell growth // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from direct assay /// 0034695 // response to prostaglandin E // inferred from direct assay /// 0034699 // response to luteinizing hormone // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060038 // cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034673 // inhibin-betaglycan-ActRII complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0015026 // coreceptor activity // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from mutant phenotype /// 0048185 // activin binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0070123 // transforming growth factor beta receptor activity, type III // inferred from direct assay 204732_s_at AI021991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI021991 /FEA=EST /DB_XREF=gi:3239344 /DB_XREF=est:ox04g08.x1 /CLONE=IMAGE:1655390 /UG=Hs.792 ADP-ribosylation factor domain protein 1, 64kD /FL=gb:AF230397.1 gb:L04510.1 gb:NM_001656.1 AI021991 tripartite motif containing 23 TRIM23 373 NM_001656 /// NM_033227 /// NM_033228 /// XM_005248497 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0000139 // Golgi membrane // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204733_at NM_002774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002774.1 /DEF=Homo sapiens kallikrein 6 (neurosin, zyme) (KLK6), mRNA. /FEA=mRNA /GEN=KLK6 /PROD=kallikrein 6 (neurosin, zyme) /DB_XREF=gi:4506154 /UG=Hs.79361 kallikrein 6 (neurosin, zyme) /FL=gb:U62801.1 gb:D78203.1 gb:AF013988.1 gb:NM_002774.1 NM_002774 kallikrein-related peptidase 6 KLK6 5653 NM_001012964 /// NM_001012965 /// NM_001012966 /// NM_002774 0006508 // proteolysis // not recorded /// 0007417 // central nervous system development // non-traceable author statement /// 0009611 // response to wounding // non-traceable author statement /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016540 // protein autoprocessing // non-traceable author statement /// 0030574 // collagen catabolic process // non-traceable author statement /// 0042246 // tissue regeneration // non-traceable author statement /// 0042445 // hormone metabolic process // non-traceable author statement /// 0042552 // myelination // non-traceable author statement /// 0042982 // amyloid precursor protein metabolic process // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0070997 // neuron death // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030141 // secretory granule // not recorded /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204734_at NM_002275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002275.1 /DEF=Homo sapiens keratin 15 (KRT15), mRNA. /FEA=mRNA /GEN=KRT15 /PROD=keratin 15 /DB_XREF=gi:4504914 /UG=Hs.80342 keratin 15 /FL=gb:BC002641.1 gb:NM_002275.1 NM_002275 keratin 15 KRT15 3866 NM_002275 /// XM_005257345 /// XM_006721891 0008544 // epidermis development // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 204735_at NM_006202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006202.1 /DEF=Homo sapiens phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2) (PDE4A), mRNA. /FEA=mRNA /GEN=PDE4A /PROD=phosphodiesterase 4A, cAMP-specific (dunce(Drosophila)-homolog phosphodiesterase E2) /DB_XREF=gi:5453861 /UG=Hs.89901 phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2) /FL=gb:U97584.1 gb:U68532.1 gb:NM_006202.1 NM_006202 phosphodiesterase 4A, cAMP-specific PDE4A 5141 NM_001111307 /// NM_001111308 /// NM_001111309 /// NM_001243121 /// NM_006202 /// XM_005259933 /// XM_006722765 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204736_s_at NM_001897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001897.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan 4 (melanoma-associated) (CSPG4), mRNA. /FEA=mRNA /GEN=CSPG4 /PROD=melanoma-associated chondroitin sulfateproteoglycan 4 /DB_XREF=gi:4503098 /UG=Hs.9004 chondroitin sulfate proteoglycan 4 (melanoma-associated) /FL=gb:NM_001897.1 NM_001897 chondroitin sulfate proteoglycan 4 CSPG4 1464 NM_001897 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 204737_s_at NM_000257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000257.1 /DEF=Homo sapiens myosin, heavy polypeptide 7, cardiac muscle, beta (MYH7), mRNA. /FEA=mRNA /GEN=MYH7 /PROD=myosin, heavy polypeptide 7, cardiac muscle,beta /DB_XREF=gi:4557772 /UG=Hs.929 myosin, heavy polypeptide 7, cardiac muscle, beta /FL=gb:M58018.1 gb:NM_000257.1 NM_000257 myosin, heavy chain 6, cardiac muscle, alpha /// myosin, heavy chain 7, cardiac muscle, beta MYH6 /// MYH7 4624 /// 4625 NM_000257 /// NM_002471 /// XM_005267694 /// XM_005267695 /// XM_005267696 /// XM_005267697 /// XM_006720151 /// XM_006720152 /// XR_245686 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0002026 // regulation of the force of heart contraction // inferred from direct assay /// 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006936 // muscle contraction // inferred from direct assay /// 0006936 // muscle contraction // traceable author statement /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from direct assay /// 0007512 // adult heart development // inferred from mutant phenotype /// 0007522 // visceral muscle development // inferred from sequence or structural similarity /// 0008016 // regulation of heart contraction // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0043462 // regulation of ATPase activity // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060420 // regulation of heart growth // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0032982 // myosin filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000146 // microfilament motor activity // inferred from sequence or structural similarity /// 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030898 // actin-dependent ATPase activity // inferred from mutant phenotype 204738_s_at NM_004912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004912.1 /DEF=Homo sapiens cerebral cavernous malformations 1 (CCM1), mRNA. /FEA=mRNA /GEN=CCM1 /PROD=ankyrin repeat-containing protein /DB_XREF=gi:4758657 /UG=Hs.93810 cerebral cavernous malformations 1 /FL=gb:U90268.1 gb:NM_004912.1 gb:AF296765.2 NM_004912 KRIT1, ankyrin repeat containing KRIT1 889 NM_001013406 /// NM_004912 /// NM_194454 /// NM_194455 /// NM_194456 /// XM_005250660 /// XM_005250662 /// XM_005250663 /// XM_005250664 /// XM_005250665 /// XM_005250666 /// XM_005250667 /// XM_005250668 /// XM_005250669 /// XM_006716160 /// XM_006716161 /// XM_006716162 /// XM_006716163 /// XM_006716164 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 204739_at NM_001812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001812.1 /DEF=Homo sapiens centromere protein C 1 (CENPC1), mRNA. /FEA=mRNA /GEN=CENPC1 /PROD=centromere protein C 1 /DB_XREF=gi:4502778 /UG=Hs.154207 centromere protein C 1 /FL=gb:M95724.1 gb:NM_001812.1 NM_001812 centromere protein C CENPC 1060 NM_001812 /// XM_006714064 /// XM_006714065 /// XR_245245 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019237 // centromeric DNA binding // inferred from electronic annotation 204740_at NM_006314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006314.1 /DEF=Homo sapiens connector enhancer of KSR-like (Drosophila kinase suppressor of ras) (CNK1), mRNA. /FEA=mRNA /GEN=CNK1 /PROD=connector enhancer of KSR-like (Drosophilakinase suppressor of ras) /DB_XREF=gi:5453622 /UG=Hs.16232 connector enhancer of KSR-like (Drosophila kinase suppressor of ras) /FL=gb:AF100153.1 gb:NM_006314.1 NM_006314 connector enhancer of kinase suppressor of Ras 1 CNKSR1 10256 NM_006314 /// NR_023345 /// XM_006710279 /// XM_006710280 /// XM_006710281 /// XM_006710282 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from physical interaction /// 0007266 // Rho protein signal transduction // inferred from physical interaction /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay 204741_at NM_001714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001714.1 /DEF=Homo sapiens Bicaudal D (Drosophila) homolog 1 (BICD1), mRNA. /FEA=mRNA /GEN=BICD1 /PROD=Bicaudal D (Drosophila) homolog 1 /DB_XREF=gi:4502408 /UG=Hs.164975 Bicaudal D (Drosophila) homolog 1 /FL=gb:U90028.1 gb:NM_001714.1 NM_001714 bicaudal D homolog 1 (Drosophila) BICD1 636 NM_001003398 /// NM_001714 /// XM_005253465 /// XM_005253466 /// XM_006719134 /// XR_242898 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008298 // intracellular mRNA localization // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from direct assay /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072385 // minus-end-directed organelle transport along microtubule // inferred from mutant phenotype /// 0072393 // microtubule anchoring at microtubule organizing center // inferred from sequence or structural similarity /// 1900275 // negative regulation of phospholipase C activity // inferred from sequence or structural similarity /// 1900276 // regulation of proteinase activated receptor activity // inferred from sequence or structural similarity /// 1900737 // negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045298 // tubulin complex // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072517 // host cell viral assembly compartment // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0031871 // proteinase activated receptor binding // inferred from sequence or structural similarity /// 0034452 // dynactin binding // inferred from direct assay /// 0045502 // dynein binding // inferred from direct assay 204742_s_at NM_015032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015032.1 /DEF=Homo sapiens KIAA0979 protein (KIAA0979), mRNA. /FEA=mRNA /GEN=KIAA0979 /PROD=KIAA0979 protein /DB_XREF=gi:7657268 /UG=Hs.168625 androgen-induced prostate proliferative shutoff associated protein /FL=gb:NM_015032.1 NM_015032 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) PDS5B 23047 NM_015032 /// NM_015928 /// XM_005266295 /// XM_005266296 /// XM_005266297 /// XM_005266298 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement 204743_at NM_013259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013259.1 /DEF=Homo sapiens neuronal protein (NP25), mRNA. /FEA=mRNA /GEN=NP25 /PROD=neuronal protein /DB_XREF=gi:10047091 /UG=Hs.169330 neuronal protein /FL=gb:NM_013259.1 gb:AF112201.1 NM_013259 transgelin 3 TAGLN3 29114 NM_001008272 /// NM_001008273 /// NM_013259 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204744_s_at NM_013417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013417.1 /DEF=Homo sapiens isoleucine-tRNA synthetase (IARS), transcript variant long, mRNA. /FEA=mRNA /GEN=IARS /PROD=isoleucine-tRNA synthetase /DB_XREF=gi:7770071 /UG=Hs.172801 isoleucine-tRNA synthetase /FL=gb:U04953.1 gb:D28473.1 gb:NM_013417.1 NM_013417 isoleucyl-tRNA synthetase IARS 3376 NM_002161 /// NM_013417 /// NR_073446 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006428 // isoleucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004822 // isoleucine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204745_x_at NM_005950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005950.1 /DEF=Homo sapiens metallothionein 1G (MT1G), mRNA. /FEA=mRNA /GEN=MT1G /PROD=metallothionein 1G /DB_XREF=gi:10835229 /UG=Hs.173451 metallothionein 1G /FL=gb:NM_005950.1 NM_005950 metallothionein 1G MT1G 4495 NM_005950 0030224 // monocyte differentiation // non-traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from expression pattern /// 0042117 // monocyte activation // non-traceable author statement /// 0045926 // negative regulation of growth // inferred from direct assay /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071280 // cellular response to copper ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from direct assay /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204746_s_at NM_012407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012407.1 /DEF=Homo sapiens protein kinase C, alpha binding protein (PRKCABP), mRNA. /FEA=mRNA /GEN=PRKCABP /PROD=protein kinase C, alpha binding protein /DB_XREF=gi:7110696 /UG=Hs.180871 protein kinase C, alpha binding protein /FL=gb:AB026491.1 gb:NM_012407.1 gb:AF231710.1 NM_012407 protein interacting with PRKCA 1 PICK1 9463 NM_001039583 /// NM_001039584 /// NM_012407 /// XM_006724377 /// XM_006724378 /// XM_006724379 /// XM_006724380 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // non-traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0034316 // negative regulation of Arp2/3 complex-mediated actin nucleation // inferred from sequence or structural similarity /// 0036294 // cellular response to decreased oxygen levels // inferred from sequence or structural similarity /// 0042149 // cellular response to glucose starvation // inferred from sequence or structural similarity /// 0043045 // DNA methylation involved in embryo development // non-traceable author statement /// 0043046 // DNA methylation involved in gamete generation // traceable author statement /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0045161 // neuronal ion channel clustering // traceable author statement /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0097061 // dendritic spine organization // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0042734 // presynaptic membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0071933 // Arp2/3 complex binding // inferred from sequence or structural similarity 204747_at NM_001549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001549.1 /DEF=Homo sapiens interferon-induced protein with tetratricopeptide repeats 4 (IFIT4), mRNA. /FEA=mRNA /GEN=IFIT4 /PROD=interferon-induced protein withtetratricopeptide repeats 4 /DB_XREF=gi:4504586 /UG=Hs.181874 interferon-induced protein with tetratricopeptide repeats 4 /FL=gb:BC001383.1 gb:BC004977.1 gb:U52513.1 gb:AF026939.1 gb:AF083470.1 gb:NM_001549.1 NM_001549 interferon-induced protein with tetratricopeptide repeats 3 IFIT3 3437 NM_001031683 /// NM_001289758 /// NM_001289759 /// NM_001549 0002376 // immune system process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035457 // cellular response to interferon-alpha // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204748_at NM_000963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000963.1 /DEF=Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin GH synthase and cyclooxygenase) (PTGS2), mRNA. /FEA=mRNA /GEN=PTGS2 /PROD=prostaglandin-endoperoxide synthase 2(prostaglandin GH synthase and cyclooxygenase) /DB_XREF=gi:4506264 /UG=Hs.196384 prostaglandin-endoperoxide synthase 2 (prostaglandin GH synthase and cyclooxygenase) /FL=gb:M90100.1 gb:L15326.1 gb:NM_000963.1 NM_000963 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) PTGS2 5743 NM_000963 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0001516 // prostaglandin biosynthetic process // non-traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009750 // response to fructose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // inferred from direct assay /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // non-traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0031915 // positive regulation of synaptic plasticity // inferred from electronic annotation /// 0032227 // negative regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035633 // maintenance of blood-brain barrier // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042633 // hair cycle // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // non-traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071318 // cellular response to ATP // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071636 // positive regulation of transforming growth factor beta production // inferred from sequence or structural similarity /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0090271 // positive regulation of fibroblast growth factor production // inferred from sequence or structural similarity /// 0090336 // positive regulation of brown fat cell differentiation // inferred from sequence or structural similarity /// 0090362 // positive regulation of platelet-derived growth factor production // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004601 // peroxidase activity // non-traceable author statement /// 0004666 // prostaglandin-endoperoxide synthase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050473 // arachidonate 15-lipoxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 204749_at NM_004538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004538.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 3 (NAP1L3), mRNA. /FEA=mRNA /GEN=NAP1L3 /PROD=nucleosome assembly protein 1-like 3 /DB_XREF=gi:4758757 /UG=Hs.21365 nucleosome assembly protein 1-like 3 /FL=gb:D50370.1 gb:NM_004538.1 NM_004538 nucleosome assembly protein 1-like 3 NAP1L3 4675 NM_004538 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 204750_s_at BF196457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196457 /FEA=EST /DB_XREF=gi:11084425 /DB_XREF=est:hr86d10.x1 /CLONE=IMAGE:3135379 /UG=Hs.239727 desmocollin 2 /FL=gb:NM_004949.1 BF196457 desmocollin 2 DSC2 1824 NM_004949 /// NM_024422 /// XM_005258206 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086042 // cardiac muscle cell-cardiac muscle cell adhesion // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204751_x_at NM_004949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004949.1 /DEF=Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2b, mRNA. /FEA=mRNA /GEN=DSC2 /PROD=desmocollin 2, isoform Dsc2b preproprotein /DB_XREF=gi:13435365 /UG=Hs.239727 desmocollin 2 /FL=gb:NM_004949.1 NM_004949 desmocollin 2 DSC2 1824 NM_004949 /// NM_024422 /// XM_005258206 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086042 // cardiac muscle cell-cardiac muscle cell adhesion // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204752_x_at NM_005484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005484.2 /DEF=Homo sapiens ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 (ADPRTL2), mRNA. /FEA=mRNA /GEN=ADPRTL2 /PROD=poly (ADP-ribosyl) transferase-like 2 /DB_XREF=gi:11496991 /UG=Hs.24284 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 /FL=gb:NM_005484.2 gb:AF085734.1 NM_005484 poly (ADP-ribose) polymerase 2 PARP2 10038 NM_001042618 /// NM_005484 /// XM_005267247 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 204753_s_at AI810712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI810712 /FEA=EST /DB_XREF=gi:5397278 /DB_XREF=est:tt86f08.x1 /CLONE=IMAGE:2248455 /UG=Hs.250692 hepatic leukemia factor /FL=gb:M95585.1 gb:NM_002126.1 AI810712 hepatic leukemia factor HLF 3131 NM_002126 /// XM_005257269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204754_at W60800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W60800 /FEA=EST /DB_XREF=gi:1367644 /DB_XREF=est:zd27d08.s1 /CLONE=IMAGE:341871 /UG=Hs.250692 hepatic leukemia factor /FL=gb:M95585.1 gb:NM_002126.1 W60800 hepatic leukemia factor HLF 3131 NM_002126 /// XM_005257269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204755_x_at M95585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M95585.1 /DEF=Human hepatic leukemia factor (HLF) mRNA, complete cds. /FEA=mRNA /GEN=HLF /PROD=hepatic leukemia factor /DB_XREF=gi:184223 /UG=Hs.250692 hepatic leukemia factor /FL=gb:M95585.1 gb:NM_002126.1 M95585 hepatic leukemia factor HLF 3131 NM_002126 /// XM_005257269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204756_at NM_002757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002757.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), mRNA. /FEA=mRNA /GEN=MAP2K5 /PROD=mitogen-activated protein kinase kinase 5 /DB_XREF=gi:4506100 /UG=Hs.250870 mitogen-activated protein kinase kinase 5 /FL=gb:U25265.1 gb:NM_002757.1 NM_002757 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204757_s_at R61539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R61539 /FEA=EST /DB_XREF=gi:832234 /DB_XREF=est:yh16f01.s1 /CLONE=IMAGE:37799 /UG=Hs.26899 KIAA0285 gene product /FL=gb:AB006623.1 gb:NM_014807.1 R61539 C2CD2-like C2CD2L 9854 NM_001290474 /// NM_014807 /// XM_005271738 /// XM_005271739 /// XM_005271740 /// XM_005271741 /// XM_005271742 /// XM_006718948 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204758_s_at NM_014807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014807.1 /DEF=Homo sapiens KIAA0285 gene product (KIAA0285), mRNA. /FEA=mRNA /GEN=KIAA0285 /PROD=KIAA0285 gene product /DB_XREF=gi:7662039 /UG=Hs.26899 KIAA0285 gene product /FL=gb:AB006623.1 gb:NM_014807.1 NM_014807 C2CD2-like C2CD2L 9854 NM_001290474 /// NM_014807 /// XM_005271738 /// XM_005271739 /// XM_005271740 /// XM_005271741 /// XM_005271742 /// XM_006718948 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204759_at NM_001268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001268.1 /DEF=Homo sapiens chromosome condensation 1-like (CHC1L), mRNA. /FEA=mRNA /GEN=CHC1L /PROD=RCC1-like G exchanging factor RLG /DB_XREF=gi:4557444 /UG=Hs.27007 chromosome condensation 1-like /FL=gb:AF060219.1 gb:NM_001268.1 NM_001268 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 RCBTB2 1102 NM_001268 /// NM_001286830 /// NM_001286831 /// NM_001286832 /// XM_005266242 /// XM_005266244 /// XM_006719758 /// XM_006719759 0032316 // regulation of Ran GTPase activity // traceable author statement /// 0032853 // positive regulation of Ran GTPase activity // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation 0005087 // Ran guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204760_s_at NM_021724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021724.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group D, member 1 (NR1D1), mRNA. /FEA=mRNA /GEN=NR1D1 /PROD=nuclear receptor subfamily 1, group D, member 1 /DB_XREF=gi:13430847 /UG=Hs.276916 nuclear receptor subfamily 1, group D, member 1 /FL=gb:NM_021724.1 gb:M24898.1 NM_021724 nuclear receptor subfamily 1, group D, member 1 /// thyroid hormone receptor, alpha NR1D1 /// THRA 7067 /// 9572 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_021724 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 204761_at NM_014688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014688.1 /DEF=Homo sapiens related to the N terminus of tre (RNTRE), mRNA. /FEA=mRNA /GEN=RNTRE /PROD=related to the N terminus of tre /DB_XREF=gi:7661863 /UG=Hs.278526 related to the N terminus of tre /FL=gb:D13644.1 gb:NM_014688.1 NM_014688 USP6 N-terminal like /// USP6NL intronic transcript 1 (non-protein coding) USP6NL /// USP6NL-IT1 9712 /// 100507213 NM_001080491 /// NM_014688 /// XM_006717542 /// XR_109008 /// XR_171839 /// XR_247492 0007030 // Golgi organization // inferred from mutant phenotype /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0035526 // retrograde transport, plasma membrane to Golgi // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay 204762_s_at BE670563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE670563 /FEA=EST /DB_XREF=gi:10031104 /DB_XREF=est:7e36f10.x1 /CLONE=IMAGE:3284587 /UG=Hs.296184 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O /FL=gb:NM_020988.1 BE670563 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GNAO1 2775 NM_020988 /// NM_138736 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007212 // dopamine receptor signaling pathway // not recorded /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation 204763_s_at NM_020988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020988.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), mRNA. /FEA=mRNA /GEN=GNAO1 /PROD=guanine nucleotide binding protein (G protein),alpha activating activity polypeptide O /DB_XREF=gi:10567815 /UG=Hs.296184 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O /FL=gb:NM_020988.1 NM_020988 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GNAO1 2775 NM_020988 /// NM_138736 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007212 // dopamine receptor signaling pathway // not recorded /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation 204764_at NM_002028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002028.1 /DEF=Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA. /FEA=mRNA /GEN=FNTB /PROD=farnesyltransferase, CAAX box, beta /DB_XREF=gi:10835058 /UG=Hs.322659 farnesyltransferase, CAAX box, beta /FL=gb:NM_002028.1 gb:L00635.1 gb:L10414.1 NM_002028 CHURC1-FNTB readthrough /// farnesyltransferase, CAAX box, beta CHURC1-FNTB /// FNTB 2342 /// 100529261 NM_001202558 /// NM_001202559 /// NM_002028 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018343 // protein farnesylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204765_at NM_005435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005435.1 /DEF=Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5 (ARHGEF5), mRNA. /FEA=mRNA /GEN=ARHGEF5 /PROD=Rho guanine nucleotide exchange factor (GEF) 5 /DB_XREF=gi:4885632 /UG=Hs.334 Rho guanine nucleotide exchange factor (GEF) 5 /FL=gb:U02082.1 gb:NM_005435.1 NM_005435 Rho guanine nucleotide exchange factor (GEF) 5 ARHGEF5 7984 NM_001002861 /// NM_005435 /// XM_006716127 /// XM_006716128 0002408 // myeloid dendritic cell chemotaxis // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation 204766_s_at NM_002452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002452.1 /DEF=Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), mRNA. /FEA=mRNA /GEN=NUDT1 /PROD=nudix (nucleoside diphosphate linked moietyX)-type motif 1 /DB_XREF=gi:4505274 /UG=Hs.388 nudix (nucleoside diphosphate linked moiety X)-type motif 1 /FL=gb:D16581.1 gb:NM_002452.1 gb:AB025233.1 gb:AB025235.1 gb:AB025237.1 gb:AB025239.1 gb:AB025240.1 gb:AB025241.1 gb:AB025242.1 NM_002452 nudix (nucleoside diphosphate linked moiety X)-type motif 1 NUDT1 4521 NM_002452 /// NM_198948 /// NM_198949 /// NM_198950 /// NM_198952 /// NM_198953 /// NM_198954 0006184 // GTP catabolic process // inferred from direct assay /// 0006195 // purine nucleotide catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006203 // dGTP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred by curator /// 0006298 // mismatch repair // inferred by curator /// 0006979 // response to oxidative stress // traceable author statement /// 0034656 // nucleobase-containing small molecule catabolic process // traceable author statement /// 0042262 // DNA protection // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046061 // dATP catabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0008413 // 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0035539 // 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047693 // ATP diphosphatase activity // inferred from direct assay /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity 204767_s_at BC000323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000323.1 /DEF=Homo sapiens, flap structure-specific endonuclease 1, clone MGC:8478, mRNA, complete cds. /FEA=mRNA /PROD=flap structure-specific endonuclease 1 /DB_XREF=gi:12653112 /UG=Hs.4756 flap structure-specific endonuclease 1 /FL=gb:BC000323.1 gb:NM_004111.3 BC000323 flap structure-specific endonuclease 1 FEN1 2237 NM_004111 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009650 // UV protection // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043137 // DNA replication, removal of RNA primer // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from direct assay /// 0004527 // exonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008309 // double-stranded DNA exodeoxyribonuclease activity // traceable author statement /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0017108 // 5'-flap endonuclease activity // inferred from mutant phenotype /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048256 // flap endonuclease activity // inferred from electronic annotation 204768_s_at NM_004111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004111.3 /DEF=Homo sapiens flap structure-specific endonuclease 1 (FEN1), mRNA. /FEA=mRNA /GEN=FEN1 /PROD=flap structure-specific endonuclease 1 /DB_XREF=gi:6325465 /UG=Hs.4756 flap structure-specific endonuclease 1 /FL=gb:BC000323.1 gb:NM_004111.3 NM_004111 flap structure-specific endonuclease 1 FEN1 2237 NM_004111 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009650 // UV protection // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043137 // DNA replication, removal of RNA primer // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from direct assay /// 0004527 // exonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008309 // double-stranded DNA exodeoxyribonuclease activity // traceable author statement /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0017108 // 5'-flap endonuclease activity // inferred from mutant phenotype /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048256 // flap endonuclease activity // inferred from electronic annotation 204769_s_at M74447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74447.1 /DEF=Human PSF-2 mRNA, complete cds. /FEA=mRNA /GEN=PSF-2 /DB_XREF=gi:188505 /UG=Hs.502 ATP-binding cassette, sub-family B (MDRTAP), member 3 /FL=gb:BC002751.1 gb:M74447.1 gb:Z22935.1 gb:Z22936.1 gb:NM_000544.2 M74447 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) TAP2 6891 NM_000544 /// NM_001290043 /// NM_018833 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // not recorded /// 0002485 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent // not recorded /// 0002489 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent // inferred from mutant phenotype /// 0002591 // positive regulation of antigen processing and presentation of peptide antigen via MHC class I // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015833 // peptide transport // traceable author statement /// 0015833 // peptide transport // /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from direct assay /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0046967 // cytosol to ER transport // inferred from mutant phenotype /// 0046968 // peptide antigen transport // inferred from direct assay /// 0046968 // peptide antigen transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015197 // peptide transporter activity // inferred from genetic interaction /// 0015421 // oligopeptide-transporting ATPase activity // /// 0015433 // peptide antigen-transporting ATPase activity // inferred from mutant phenotype /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // /// 0042605 // peptide antigen binding // /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // /// 0046980 // tapasin binding // inferred from sequence or structural similarity 204770_at NM_000544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000544.2 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 3 (ABCB3), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCB3 /PROD=ATP-binding cassette, sub-family B, member 3,isoform 1 /DB_XREF=gi:9961245 /UG=Hs.502 ATP-binding cassette, sub-family B (MDRTAP), member 3 /FL=gb:BC002751.1 gb:M74447.1 gb:Z22935.1 gb:Z22936.1 gb:NM_000544.2 NM_000544 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) TAP2 6891 NM_000544 /// NM_001290043 /// NM_018833 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // not recorded /// 0002485 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent // not recorded /// 0002489 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent // inferred from mutant phenotype /// 0002591 // positive regulation of antigen processing and presentation of peptide antigen via MHC class I // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015833 // peptide transport // traceable author statement /// 0015833 // peptide transport // /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from direct assay /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0046967 // cytosol to ER transport // inferred from mutant phenotype /// 0046968 // peptide antigen transport // inferred from direct assay /// 0046968 // peptide antigen transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015197 // peptide transporter activity // inferred from genetic interaction /// 0015421 // oligopeptide-transporting ATPase activity // /// 0015433 // peptide antigen-transporting ATPase activity // inferred from mutant phenotype /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // /// 0042605 // peptide antigen binding // /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // /// 0046980 // tapasin binding // inferred from sequence or structural similarity 204771_s_at AI632304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI632304 /FEA=EST /DB_XREF=gi:4683634 /DB_XREF=est:tt22d02.x1 /CLONE=IMAGE:2241507 /UG=Hs.54780 transcription termination factor, RNA polymerase I /FL=gb:NM_007344.1 AI632304 transcription termination factor, RNA polymerase I TTF1 7270 NM_001205296 /// NM_007344 /// XM_006717273 /// XM_006717274 /// XM_006717275 /// XR_246601 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // inferred from electronic annotation /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204772_s_at NM_007344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007344.1 /DEF=Homo sapiens transcription termination factor, RNA polymerase I (TTF1), mRNA. /FEA=mRNA /GEN=TTF1 /PROD=transcription termination factor, RNA polymeraseI /DB_XREF=gi:6678454 /UG=Hs.54780 transcription termination factor, RNA polymerase I /FL=gb:NM_007344.1 NM_007344 transcription termination factor, RNA polymerase I TTF1 7270 NM_001205296 /// NM_007344 /// XM_006717273 /// XM_006717274 /// XM_006717275 /// XR_246601 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // inferred from electronic annotation /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204773_at NM_004512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004512.1 /DEF=Homo sapiens interleukin 11 receptor, alpha (IL11RA), mRNA. /FEA=mRNA /GEN=IL11RA /PROD=interleukin 11 receptor, alpha /DB_XREF=gi:4758593 /UG=Hs.64310 interleukin 11 receptor, alpha /FL=gb:BC003110.1 gb:NM_004512.1 gb:U32324.1 NM_004512 interleukin 11 receptor, alpha IL11RA 3590 NM_001142784 /// NM_004512 /// NM_147162 /// NR_052010 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032502 // developmental process // inferred from mutant phenotype /// 0060322 // head development // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204774_at NM_014210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014210.1 /DEF=Homo sapiens ecotropic viral integration site 2A (EVI2A), mRNA. /FEA=mRNA /GEN=EVI2A /PROD=ecotropic viral integration site 2A /DB_XREF=gi:7657074 /UG=Hs.70499 ecotropic viral integration site 2A /FL=gb:NM_014210.1 NM_014210 ecotropic viral integration site 2A EVI2A 2123 NM_001003927 /// NM_014210 0007165 // signal transduction // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement 204775_at NM_005441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005441.1 /DEF=Homo sapiens chromatin assembly factor 1, subunit B (p60) (CHAF1B), mRNA. /FEA=mRNA /GEN=CHAF1B /PROD=chromatin assembly factor 1, subunit B (p60) /DB_XREF=gi:4885104 /UG=Hs.75238 chromatin assembly factor 1, subunit B (p60) /FL=gb:NM_005441.1 gb:U20980.1 NM_005441 chromatin assembly factor 1, subunit B (p60) CHAF1B 8208 NM_005441 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042393 // histone binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 204776_at NM_003248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003248.1 /DEF=Homo sapiens thrombospondin 4 (THBS4), mRNA. /FEA=mRNA /GEN=THBS4 /PROD=thrombospondin 4 /DB_XREF=gi:4507488 /UG=Hs.75774 thrombospondin 4 /FL=gb:NM_003248.1 NM_003248 thrombospondin 4 THBS4 7060 NM_003248 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from expression pattern /// 0034103 // regulation of tissue remodeling // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051451 // myoblast migration // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005178 // integrin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay 204777_s_at NM_002371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002371.2 /DEF=Homo sapiens mal, T-cell differentiation protein (MAL), transcript variant a, mRNA. /FEA=mRNA /GEN=MAL /PROD=T-cell differentiation protein MAL, isoform a /DB_XREF=gi:12408666 /UG=Hs.80395 mal, T-cell differentiation protein /FL=gb:NM_002371.2 gb:BC000458.1 gb:BC003006.1 gb:M15800.1 NM_002371 mal, T-cell differentiation protein MAL 4118 NM_002371 /// NM_022438 /// NM_022439 /// NM_022440 0001766 // membrane raft polarization // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0030154 // cell differentiation // traceable author statement /// 0042552 // myelination // non-traceable author statement /// 0042552 // myelination // traceable author statement /// 0045176 // apical protein localization // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // traceable author statement /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0015267 // channel activity // traceable author statement /// 0016505 // peptidase activator activity involved in apoptotic process // non-traceable author statement /// 0019911 // structural constituent of myelin sheath // inferred from direct assay 204778_x_at AW102783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW102783 /FEA=EST /DB_XREF=gi:6073396 /DB_XREF=est:xd38a03.x1 /CLONE=IMAGE:2596012 /UG=Hs.819 homeo box B7 /FL=gb:M16937.1 gb:NM_004502.1 AW102783 homeobox B7 HOXB7 3217 NM_004502 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204779_s_at NM_004502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004502.1 /DEF=Homo sapiens homeo box B7 (HOXB7), mRNA. /FEA=mRNA /GEN=HOXB7 /PROD=homeo box B7 /DB_XREF=gi:4758551 /UG=Hs.819 homeo box B7 /FL=gb:M16937.1 gb:NM_004502.1 NM_004502 homeobox B7 HOXB7 3217 NM_004502 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204780_s_at AA164751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA164751 /FEA=EST /DB_XREF=gi:1740929 /DB_XREF=est:zo93g12.s1 /CLONE=IMAGE:594502 /UG=Hs.82359 tumor necrosis factor receptor superfamily, member 6 /FL=gb:M67454.1 gb:NM_000043.1 AA164751 Fas cell surface death receptor FAS 355 NM_000043 /// NM_152871 /// NM_152872 /// NM_152873 /// NM_152874 /// NM_152875 /// NM_152876 /// NM_152877 /// NR_028033 /// NR_028034 /// NR_028035 /// NR_028036 /// XM_006717819 0002377 // immunoglobulin production // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006927 // transformed cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0019724 // B cell mediated immunity // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204781_s_at NM_000043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000043.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 6 (TNFRSF6), mRNA. /FEA=mRNA /GEN=TNFRSF6 /PROD=apoptosis (APO-1) antigen 1 /DB_XREF=gi:4507582 /UG=Hs.82359 tumor necrosis factor receptor superfamily, member 6 /FL=gb:M67454.1 gb:NM_000043.1 NM_000043 Fas cell surface death receptor FAS 355 NM_000043 /// NM_152871 /// NM_152872 /// NM_152873 /// NM_152874 /// NM_152875 /// NM_152876 /// NM_152877 /// NR_028033 /// NR_028034 /// NR_028035 /// NR_028036 /// XM_006717819 0002377 // immunoglobulin production // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006927 // transformed cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0019724 // B cell mediated immunity // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204782_at NM_022443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_022443.1 /DEF=Homo sapiens myeloid leukemia factor 1 (MLF1), mRNA. /FEA=mRNA /GEN=MLF1 /PROD=myeloid leukemia factor 1 /DB_XREF=gi:11967974 /UG=Hs.85195 myeloid leukemia factor 1 /FL=gb:NM_022443.1 NM_022443 204783_at AI911434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI911434 /FEA=EST /DB_XREF=gi:5631170 /DB_XREF=est:wd25a11.x1 /CLONE=IMAGE:2329148 /UG=Hs.85195 myeloid leukemia factor 1 /FL=gb:NM_022443.1 AI911434 myeloid leukemia factor 1 MLF1 4291 NM_001130156 /// NM_001130157 /// NM_001195432 /// NM_001195433 /// NM_001195434 /// NM_022443 /// XM_005247479 /// XM_005247480 /// XM_006713645 0002318 // myeloid progenitor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from direct assay 204784_s_at NM_022443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022443.1 /DEF=Homo sapiens myeloid leukemia factor 1 (MLF1), mRNA. /FEA=mRNA /GEN=MLF1 /PROD=myeloid leukemia factor 1 /DB_XREF=gi:11967974 /UG=Hs.85195 myeloid leukemia factor 1 /FL=gb:NM_022443.1 NM_022443 myeloid leukemia factor 1 MLF1 4291 NM_001130156 /// NM_001130157 /// NM_001195432 /// NM_001195433 /// NM_001195434 /// NM_022443 /// XM_005247479 /// XM_005247480 /// XM_006713645 0002318 // myeloid progenitor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from direct assay 204785_x_at NM_000874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000874.1 /DEF=Homo sapiens interferon (alpha, beta and omega) receptor 2 (IFNAR2), mRNA. /FEA=mRNA /GEN=IFNAR2 /PROD=interferon (alpha, beta and omega) receptor 2 /DB_XREF=gi:4504600 /UG=Hs.86958 interferon (alpha, beta and omega) receptor 2 /FL=gb:NM_000874.1 gb:L41944.1 NM_000874 interferon (alpha, beta and omega) receptor 2 IFNAR2 3455 NM_000874 /// NM_001289125 /// NM_001289126 /// NM_001289128 /// NM_207584 /// NM_207585 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004905 // type I interferon receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019962 // type I interferon binding // inferred from physical interaction 204786_s_at L41944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L41944.1 /DEF=Homo sapiens interferon receptor ifnar2-1 (splice variant IFNAR2-1) mRNA, complete cds. /FEA=mRNA /GEN=IFNAR2 /PROD=interferon receptor /DB_XREF=gi:995296 /UG=Hs.86958 interferon (alpha, beta and omega) receptor 2 /FL=gb:NM_000874.1 gb:L41944.1 L41944 interferon (alpha, beta and omega) receptor 2 IFNAR2 3455 NM_000874 /// NM_001289125 /// NM_001289126 /// NM_001289128 /// NM_207584 /// NM_207585 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004905 // type I interferon receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019962 // type I interferon binding // inferred from physical interaction 204787_at NM_007268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007268.1 /DEF=Homo sapiens Ig superfamily protein (Z39IG), mRNA. /FEA=mRNA /GEN=Z39IG /PROD=Ig superfamily protein /DB_XREF=gi:6005957 /UG=Hs.8904 Ig superfamily protein /FL=gb:NM_007268.1 NM_007268 V-set and immunoglobulin domain containing 4 VSIG4 11326 NM_001100431 /// NM_001184830 /// NM_001184831 /// NM_001257403 /// NM_007268 0002376 // immune system process // inferred from electronic annotation /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204788_s_at NM_000309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000309.1 /DEF=Homo sapiens protoporphyrinogen oxidase (PPOX), mRNA. /FEA=mRNA /GEN=PPOX /PROD=protoporphyrinogen oxidase /DB_XREF=gi:4506000 /UG=Hs.100016 protoporphyrinogen oxidase /FL=gb:NM_000309.1 gb:D38537.1 NM_000309 protoporphyrinogen oxidase PPOX 5498 NM_000309 /// NM_001122764 /// XM_005245291 /// XM_005245295 /// XM_006711402 /// XM_006711403 /// XM_006711404 /// XM_006711405 /// XM_006711406 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from direct assay /// 0006783 // heme biosynthetic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031304 // intrinsic component of mitochondrial inner membrane // inferred from sequence or structural similarity /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from mutant phenotype 0004729 // oxygen-dependent protoporphyrinogen oxidase activity // inferred from direct assay /// 0004729 // oxygen-dependent protoporphyrinogen oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // traceable author statement 204789_at NM_005892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005892.1 /DEF=Homo sapiens formin-like (FMNL), mRNA. /FEA=mRNA /GEN=FMNL /PROD=formin-like /DB_XREF=gi:5174400 /UG=Hs.100217 formin-like /FL=gb:BC001710.1 gb:NM_005892.1 NM_005892 formin-like 1 FMNL1 752 NM_005892 /// XM_006722062 /// XM_006722063 /// XM_006722064 /// XM_006722065 /// XM_006722066 /// XM_006722067 /// XM_006722068 /// XM_006722069 /// XM_006722070 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009987 // cellular process // inferred from electronic annotation /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0051014 // actin filament severing // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity 204790_at NM_005904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005904.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 7 (MADH7), mRNA. /FEA=mRNA /GEN=MADH7 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 7 /DB_XREF=gi:5174516 /UG=Hs.100602 MAD (mothers against decapentaplegic, Drosophila) homolog 7 /FL=gb:AF010193.1 gb:AF015261.1 gb:NM_005904.1 NM_005904 SMAD family member 7 SMAD7 4092 NM_001190821 /// NM_001190822 /// NM_001190823 /// NM_005904 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred by curator /// 0010719 // negative regulation of epithelial to mesenchymal transition // traceable author statement /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred by curator /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030336 // negative regulation of cell migration // traceable author statement /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0034629 // cellular protein complex localization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred by curator /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction 204791_at NM_003297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003297.1 /DEF=Homo sapiens nuclear receptor subfamily 2, group C, member 1 (NR2C1), mRNA. /FEA=mRNA /GEN=NR2C1 /PROD=nuclear receptor subfamily 2, group C, member 1 /DB_XREF=gi:4507672 /UG=Hs.108301 nuclear receptor subfamily 2, group C, member 1 /FL=gb:M29960.1 gb:NM_003297.1 NM_003297 nuclear receptor subfamily 2, group C, member 1 NR2C1 7181 NM_001032287 /// NM_001127362 /// NM_003297 /// XM_005269133 /// XM_006719584 /// XM_006719585 /// XM_006719586 /// XR_245956 /// XR_429114 /// XR_429115 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204792_s_at NM_014714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014714.1 /DEF=Homo sapiens KIAA0590 gene product (KIAA0590), mRNA. /FEA=mRNA /GEN=KIAA0590 /PROD=KIAA0590 gene product /DB_XREF=gi:7662193 /UG=Hs.111862 KIAA0590 gene product /FL=gb:AB011162.1 gb:NM_014714.1 NM_014714 intraflagellar transport 140 homolog (Chlamydomonas) IFT140 9742 NM_014714 /// XM_005255725 /// XM_005255726 /// XM_006720989 /// XM_006720990 /// XM_006720991 /// XM_006720992 0007154 // cell communication // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from mutant phenotype /// 0061512 // protein localization to cilium // inferred from mutant phenotype /// 0072001 // renal system development // inferred from mutant phenotype /// 1902017 // regulation of cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204793_at NM_014710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014710.1 /DEF=Homo sapiens KIAA0443 gene product (KIAA0443), mRNA. /FEA=mRNA /GEN=KIAA0443 /PROD=KIAA0443 gene product /DB_XREF=gi:7662129 /UG=Hs.113082 KIAA0443 gene product /FL=gb:AB007903.1 gb:NM_014710.1 NM_014710 G protein-coupled receptor associated sorting protein 1 GPRASP1 9737 NM_001099410 /// NM_001099411 /// NM_001184727 /// NM_014710 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 1990172 // G-protein coupled receptor catabolic process // inferred from mutant phenotype /// 1990172 // G-protein coupled receptor catabolic process // inferred from physical interaction 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204794_at NM_004418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004418.2 /DEF=Homo sapiens dual specificity phosphatase 2 (DUSP2), mRNA. /FEA=mRNA /GEN=DUSP2 /PROD=dual specificity phosphatase 2 /DB_XREF=gi:12707563 /UG=Hs.1183 dual specificity phosphatase 2 /FL=gb:NM_004418.2 gb:L11329.1 NM_004418 dual specificity phosphatase 2 DUSP2 1844 NM_004418 0000188 // inactivation of MAPK activity // traceable author statement /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0042981 // regulation of apoptotic process // 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 204795_at NM_025263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025263.1 /DEF=Homo sapiens CAT56 protein (CAT56), mRNA. /FEA=mRNA /GEN=CAT56 /PROD=CAT56 protein /DB_XREF=gi:13376877 /UG=Hs.118354 CAT56 protein /FL=gb:NM_025263.1 gb:U63336.1 NM_025263 proline rich 3 PRR3 80742 NM_001077497 /// NM_025263 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204796_at AI825937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825937 /FEA=EST /DB_XREF=gi:5446608 /DB_XREF=est:to92e05.x1 /CLONE=IMAGE:2185760 /UG=Hs.12451 echinoderm microtubule-associated protein-like /FL=gb:U97018.1 gb:NM_004434.1 AI825937 echinoderm microtubule associated protein like 1 EML1 2009 NM_001008707 /// NM_004434 /// XM_005267397 /// XM_005267398 /// XM_005267399 /// XM_005267400 /// XM_006720074 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0007052 // mitotic spindle organization // inferred from sequence or structural similarity /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from mutant phenotype /// 0007420 // brain development // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0097431 // mitotic spindle pole // inferred from sequence or structural similarity /// 1990023 // mitotic spindle midzone // inferred from sequence or structural similarity 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015631 // tubulin binding // inferred from direct assay 204797_s_at NM_004434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004434.1 /DEF=Homo sapiens echinoderm microtubule-associated protein-like (EMAPL), mRNA. /FEA=mRNA /GEN=EMAPL /PROD=echinoderm microtubule-associated protein-like /DB_XREF=gi:4758267 /UG=Hs.12451 echinoderm microtubule-associated protein-like /FL=gb:U97018.1 gb:NM_004434.1 NM_004434 echinoderm microtubule associated protein like 1 EML1 2009 NM_001008707 /// NM_004434 /// XM_005267397 /// XM_005267398 /// XM_005267399 /// XM_005267400 /// XM_006720074 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0007052 // mitotic spindle organization // inferred from sequence or structural similarity /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from mutant phenotype /// 0007420 // brain development // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0097431 // mitotic spindle pole // inferred from sequence or structural similarity /// 1990023 // mitotic spindle midzone // inferred from sequence or structural similarity 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015631 // tubulin binding // inferred from direct assay 204798_at NM_005375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005375.1 /DEF=Homo sapiens v-myb avian myeloblastosis viral oncogene homolog (MYB), mRNA. /FEA=mRNA /GEN=MYB /PROD=v-myb avian myeloblastosis viral oncogenehomolog /DB_XREF=gi:4885496 /UG=Hs.1334 v-myb avian myeloblastosis viral oncogene homolog /FL=gb:M15024.1 gb:AF104863.1 gb:NM_005375.1 NM_005375 v-myb avian myeloblastosis viral oncogene homolog MYB 4602 NM_001130172 /// NM_001130173 /// NM_001161656 /// NM_001161657 /// NM_001161658 /// NM_001161659 /// NM_001161660 /// NM_005375 /// XM_006715495 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0045624 // positive regulation of T-helper cell differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048538 // thymus development // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // non-traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204799_at NM_014838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014838.1 /DEF=Homo sapiens KIAA0637 gene product (KIAA0637), mRNA. /FEA=mRNA /GEN=KIAA0637 /PROD=KIAA0637 gene product /DB_XREF=gi:7662217 /UG=Hs.13604 KIAA0637 gene product /FL=gb:AB014537.1 gb:NM_014838.1 NM_014838 zinc finger, BED-type containing 4 ZBED4 9889 NM_014838 /// XM_005261875 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 204800_s_at AW194384 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194384 /FEA=EST /DB_XREF=gi:6473188 /DB_XREF=est:xm16a01.x1 /CLONE=IMAGE:2684328 /UG=Hs.101821 hypothetical protein FLJ13639 /FL=gb:NM_024705.1 AW194384 dehydrogenase/reductase (SDR family) member 12 DHRS12 79758 NM_001031719 /// NM_001270424 /// NM_024705 /// XM_005266526 /// XM_005266527 /// XM_005266528 /// XM_005266529 /// XM_005266530 /// XM_005266531 /// XM_005266532 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 204801_s_at NM_024705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024705.1 /DEF=Homo sapiens hypothetical protein FLJ13639 (FLJ13639), mRNA. /FEA=mRNA /GEN=FLJ13639 /PROD=hypothetical protein FLJ13639 /DB_XREF=gi:13375996 /UG=Hs.101821 hypothetical protein FLJ13639 /FL=gb:NM_024705.1 NM_024705 dehydrogenase/reductase (SDR family) member 12 DHRS12 79758 NM_001031719 /// NM_001270424 /// NM_024705 /// XM_005266526 /// XM_005266527 /// XM_005266528 /// XM_005266529 /// XM_005266530 /// XM_005266531 /// XM_005266532 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 204802_at NM_004165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004165.1 /DEF=Homo sapiens Ras-related associated with diabetes (RRAD), mRNA. /FEA=mRNA /GEN=RRAD /PROD=Ras-related associated with diabetes /DB_XREF=gi:4759053 /UG=Hs.1027 Ras-related associated with diabetes /FL=gb:L24564.1 gb:NM_004165.1 NM_004165 Ras-related associated with diabetes RRAD 6236 NM_001128850 /// NM_004165 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 204803_s_at NM_004165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004165.1 /DEF=Homo sapiens Ras-related associated with diabetes (RRAD), mRNA. /FEA=mRNA /GEN=RRAD /PROD=Ras-related associated with diabetes /DB_XREF=gi:4759053 /UG=Hs.1027 Ras-related associated with diabetes /FL=gb:L24564.1 gb:NM_004165.1 NM_004165 Ras-related associated with diabetes RRAD 6236 NM_001128850 /// NM_004165 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 204804_at NM_003141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003141.1 /DEF=Homo sapiens Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-ARo) (SSA1), mRNA. /FEA=mRNA /GEN=SSA1 /PROD=52kD RoSSA autoantigen /DB_XREF=gi:4507226 /UG=Hs.1042 Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-ARo) /FL=gb:M34551.1 gb:M62800.1 gb:NM_003141.1 NM_003141 tripartite motif containing 21 TRIM21 6737 NM_003141 /// XM_006718283 0000209 // protein polyubiquitination // inferred from direct assay /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0090086 // negative regulation of protein deubiquitination // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204805_s_at NM_006026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006026.1 /DEF=Homo sapiens H1 histone family, member X (H1FX), mRNA. /FEA=mRNA /GEN=H1FX /PROD=H1 histone family, member X /DB_XREF=gi:5174448 /UG=Hs.109804 H1 histone family, member X /FL=gb:BC000426.1 gb:D64142.1 gb:NM_006026.1 NM_006026 H1 histone family, member X H1FX 8971 NM_006026 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204806_x_at NM_018950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018950.1 /DEF=Homo sapiens major histocompatibility complex, class I, F (HLA-F), mRNA. /FEA=mRNA /GEN=HLA-F /PROD=major histocompatibility complex, class I, F /DB_XREF=gi:9665231 /UG=Hs.110309 major histocompatibility complex, class I, F /FL=gb:NM_018950.1 NM_018950 major histocompatibility complex, class I, F HLA-F 3134 NM_001098478 /// NM_001098479 /// NM_018950 /// XM_005249054 /// XM_005272809 /// XM_005274960 /// XM_005275115 /// XM_005275390 /// XM_005275547 /// XM_005275548 /// XM_006726089 /// XM_006726090 /// XM_006726091 /// XM_006726092 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // inferred from physical interaction 204807_at BF224146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224146 /FEA=EST /DB_XREF=gi:11131394 /DB_XREF=est:7q84b07.x1 /CLONE=IMAGE:3704797 /UG=Hs.112986 transmembrane protein 5 /FL=gb:AB015633.1 gb:NM_014254.1 BF224146 transmembrane protein 5 TMEM5 10329 NM_001278237 /// NM_014254 /// XM_005268562 /// XM_005268563 /// XM_006719195 /// XM_006719196 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204808_s_at NM_014254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014254.1 /DEF=Homo sapiens transmembrane protein 5 (TMEM5), mRNA. /FEA=mRNA /GEN=TMEM5 /PROD=transmembrane protein 5 /DB_XREF=gi:7657177 /UG=Hs.112986 transmembrane protein 5 /FL=gb:AB015633.1 gb:NM_014254.1 NM_014254 transmembrane protein 5 TMEM5 10329 NM_001278237 /// NM_014254 /// XM_005268562 /// XM_005268563 /// XM_006719195 /// XM_006719196 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204809_at NM_006660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006660.3 /DEF=Homo sapiens ClpX (caseinolytic protease X, E. coli) homolog (CLPX), mRNA. /FEA=mRNA /GEN=CLPX /PROD=ClpX (caseinolytic protease X, E. coli) homolog /DB_XREF=gi:12597621 /UG=Hs.113823 ClpX (caseinolytic protease X, E. coli) homolog /FL=gb:NM_006660.3 NM_006660 caseinolytic mitochondrial matrix peptidase chaperone subunit CLPX 10845 NM_006660 /// XR_429441 0006200 // ATP catabolic process // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0009368 // endopeptidase Clp complex // inferred from direct assay /// 0009841 // mitochondrial endopeptidase Clp complex // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004176 // ATP-dependent peptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 204810_s_at NM_001824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001824.1 /DEF=Homo sapiens creatine kinase, muscle (CKM), mRNA. /FEA=mRNA /GEN=CKM /PROD=creatine kinase, muscle /DB_XREF=gi:4502852 /UG=Hs.118843 creatine kinase, muscle /FL=gb:M14780.1 gb:NM_001824.1 NM_001824 creatine kinase, muscle CKM 1158 NM_001824 /// XM_005258497 0006600 // creatine metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046314 // phosphocreatine biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204811_s_at NM_006030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006030.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 2delta subunit 2 (CACNA2D2), mRNA. /FEA=mRNA /GEN=CACNA2D2 /PROD=calcium channel, voltage-dependent, alpha2delta subunit 2 /DB_XREF=gi:5174402 /UG=Hs.127436 calcium channel, voltage-dependent, alpha 2delta subunit 2 /FL=gb:AF040709.1 gb:NM_006030.1 NM_006030 calcium channel, voltage-dependent, alpha 2/delta subunit 2 CACNA2D2 9254 NM_001005505 /// NM_001174051 /// NM_001291101 /// NM_006030 /// XM_005265581 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060024 // rhythmic synaptic transmission // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204812_at NM_004724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004724.1 /DEF=Homo sapiens ZW10 (Drosophila) homolog, centromerekinetochore protein (ZW10), mRNA. /FEA=mRNA /GEN=ZW10 /PROD=ZW10 (Drosophila) homolog,centromerekinetochore protein /DB_XREF=gi:4759343 /UG=Hs.13512 ZW10 (Drosophila) homolog, centromerekinetochore protein /FL=gb:U54996.1 gb:NM_004724.1 NM_004724 zw10 kinetochore protein ZW10 9183 NM_004724 /// XM_006718943 0000070 // mitotic sister chromatid segregation // inferred from direct assay /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007080 // mitotic metaphase plate congression // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007096 // regulation of exit from mitosis // inferred from direct assay /// 0007126 // meiotic nuclear division // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034501 // protein localization to kinetochore // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019237 // centromeric DNA binding // traceable author statement 204813_at NM_002753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002753.1 /DEF=Homo sapiens mitogen-activated protein kinase 10 (MAPK10), mRNA. /FEA=mRNA /GEN=MAPK10 /PROD=mitogen-activated protein kinase 10 /DB_XREF=gi:4506080 /UG=Hs.151051 mitogen-activated protein kinase 10 /FL=gb:U34819.1 gb:U34820.1 gb:NM_002753.1 gb:U07620.1 NM_002753 mitogen-activated protein kinase 10 MAPK10 5602 NM_002753 /// NM_138980 /// NM_138981 /// NM_138982 /// XM_005263129 /// XM_005263130 /// XM_005263131 /// XM_005263135 /// XM_005263136 /// XM_005263138 /// XM_006714267 /// XM_006714268 /// XM_006714269 /// XM_006714270 /// XM_006714271 /// XM_006714272 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from sequence or structural similarity /// 0007258 // JUN phosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004705 // JUN kinase activity // inferred from sequence or structural similarity /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204814_at NM_003716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003716.1 /DEF=Homo sapiens Ca2+-dependent activator protein for secretion (CADPS), mRNA. /FEA=mRNA /GEN=CADPS /PROD=calcium-dependent activator protein forsecretion /DB_XREF=gi:4502540 /UG=Hs.151301 Ca2+-dependent activator protein for secretion /FL=gb:U36448.1 gb:NM_003716.1 NM_003716 Ca++-dependent secretion activator CADPS 8618 NM_003716 /// NM_183393 /// NM_183394 /// XM_006713362 /// XM_006713363 /// XM_006713364 /// XM_006713365 /// XM_006713366 /// XM_006713367 /// XM_006713368 /// XM_006713369 /// XM_006713370 /// XM_006713371 /// XM_006713372 /// XM_006713373 /// XM_006713374 /// XM_006713375 /// XM_006713376 /// XM_006713377 /// XM_006713378 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 204815_s_at AI924903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924903 /FEA=EST /DB_XREF=gi:5660867 /DB_XREF=est:wn25e04.x1 /CLONE=IMAGE:2446494 /UG=Hs.151706 KIAA0134 gene product /FL=gb:D50924.1 gb:NM_014681.1 AI924903 DEAH (Asp-Glu-Ala-His) box polypeptide 34 DHX34 9704 NM_014681 /// NM_194428 /// XM_005259443 /// XR_243974 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204816_s_at NM_014681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014681.1 /DEF=Homo sapiens KIAA0134 gene product (KIAA0134), mRNA. /FEA=mRNA /GEN=KIAA0134 /PROD=KIAA0134 gene product /DB_XREF=gi:7661933 /UG=Hs.151706 KIAA0134 gene product /FL=gb:D50924.1 gb:NM_014681.1 NM_014681 DEAH (Asp-Glu-Ala-His) box polypeptide 34 DHX34 9704 NM_014681 /// NM_194428 /// XM_005259443 /// XR_243974 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204817_at NM_012291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012291.1 /DEF=Homo sapiens extra spindle poles, S. cerevisiae, homolog of (KIAA0165), mRNA. /FEA=mRNA /GEN=KIAA0165 /PROD=extra spindle poles, S. cerevisiae, homolog of /DB_XREF=gi:6912453 /UG=Hs.153479 extra spindle poles, S. cerevisiae, homolog of /FL=gb:D79987.1 gb:NM_012291.1 NM_012291 extra spindle pole bodies homolog 1 (S. cerevisiae) ESPL1 9700 NM_012291 /// XM_006719705 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0000212 // meiotic spindle organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007127 // meiosis I // inferred from electronic annotation /// 0040001 // establishment of mitotic spindle localization // non-traceable author statement /// 0045143 // homologous chromosome segregation // inferred from electronic annotation /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // non-traceable author statement /// 0045875 // negative regulation of sister chromatid cohesion // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // non-traceable author statement /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 204818_at NM_002153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002153.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 2 (HSD17B2), mRNA. /FEA=mRNA /GEN=HSD17B2 /PROD=hydroxysteroid (17-beta) dehydrogenase 2 /DB_XREF=gi:4504502 /UG=Hs.155109 hydroxysteroid (17-beta) dehydrogenase 2 /FL=gb:L11708.1 gb:NM_002153.1 NM_002153 hydroxysteroid (17-beta) dehydrogenase 2 HSD17B2 3294 NM_002153 /// XR_243405 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from direct assay 204819_at NM_004463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004463.1 /DEF=Homo sapiens faciogenital dysplasia (Aarskog-Scott syndrome) (FGD1), mRNA. /FEA=mRNA /GEN=FGD1 /PROD=faciogenital dysplasia protein /DB_XREF=gi:4758357 /UG=Hs.1572 faciogenital dysplasia (Aarskog-Scott syndrome) /FL=gb:NM_004463.1 gb:U11690.1 NM_004463 FYVE, RhoGEF and PH domain containing 1 FGD1 2245 NM_004463 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204820_s_at NM_006994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006994.2 /DEF=Homo sapiens butyrophilin, subfamily 3, member A3 (BTN3A3), mRNA. /FEA=mRNA /GEN=BTN3A3 /PROD=butyrophilin, subfamily 3, member A3 /DB_XREF=gi:6325463 /UG=Hs.167741 butyrophilin, subfamily 3, member A3 /FL=gb:U90548.1 gb:NM_006994.2 NM_006994 butyrophilin, subfamily 3, member A2 /// butyrophilin, subfamily 3, member A3 BTN3A2 /// BTN3A3 10384 /// 11118 NM_001197246 /// NM_001197247 /// NM_001197248 /// NM_001197249 /// NM_001242803 /// NM_006994 /// NM_007047 /// NM_197974 /// XM_005248827 /// XM_005248831 /// XM_005248832 /// XM_006714979 /// XM_006714980 /// XM_006714981 /// XM_006714982 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204821_at NM_006994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006994.2 /DEF=Homo sapiens butyrophilin, subfamily 3, member A3 (BTN3A3), mRNA. /FEA=mRNA /GEN=BTN3A3 /PROD=butyrophilin, subfamily 3, member A3 /DB_XREF=gi:6325463 /UG=Hs.167741 butyrophilin, subfamily 3, member A3 /FL=gb:U90548.1 gb:NM_006994.2 NM_006994 butyrophilin, subfamily 3, member A3 BTN3A3 10384 NM_001242803 /// NM_006994 /// NM_197974 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204822_at NM_003318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003318.1 /DEF=Homo sapiens TTK protein kinase (TTK), mRNA. /FEA=mRNA /GEN=TTK /PROD=TTK protein kinase /DB_XREF=gi:4507718 /UG=Hs.169840 TTK protein kinase /FL=gb:BC000633.1 gb:M86699.1 gb:NM_003318.1 NM_003318 TTK protein kinase TTK 7272 NM_001166691 /// NM_003318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007051 // spindle organization // traceable author statement /// 0007052 // mitotic spindle organization // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0051304 // chromosome separation // inferred from electronic annotation 0005819 // spindle // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 204823_at NM_014903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014903.1 /DEF=Homo sapiens KIAA0938 protein (KIAA0938), mRNA. /FEA=mRNA /GEN=KIAA0938 /PROD=KIAA0938 protein /DB_XREF=gi:7662389 /UG=Hs.174188 KIAA0938 protein /FL=gb:AB023155.1 gb:NM_014903.1 NM_014903 neuron navigator 3 NAV3 89795 NM_001024383 /// NM_014903 /// XM_005269215 /// XM_006719675 /// XM_006719676 /// XM_006719677 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204824_at NM_004435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004435.1 /DEF=Homo sapiens endonuclease G (ENDOG), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ENDOG /PROD=endonuclease G precursor /DB_XREF=gi:4758269 /UG=Hs.182418 endonuclease G /FL=gb:BC004922.1 gb:NM_004435.1 NM_004435 endonuclease G ENDOG 2021 NM_004435 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // not recorded /// 0006310 // DNA recombination // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation 0005739 // mitochondrion // not recorded 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // not recorded /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204825_at NM_014791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014791.1 /DEF=Homo sapiens KIAA0175 gene product (KIAA0175), mRNA. /FEA=mRNA /GEN=KIAA0175 /PROD=KIAA0175 gene product /DB_XREF=gi:7661973 /UG=Hs.184339 KIAA0175 gene product /FL=gb:D79997.1 gb:NM_014791.1 NM_014791 maternal embryonic leucine zipper kinase MELK 9833 NM_001256685 /// NM_001256687 /// NM_001256688 /// NM_001256689 /// NM_001256690 /// NM_001256691 /// NM_001256692 /// NM_001256693 /// NM_014791 /// NR_046337 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 204826_at NM_001761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001761.1 /DEF=Homo sapiens cyclin F (CCNF), mRNA. /FEA=mRNA /GEN=CCNF /PROD=cyclin F /DB_XREF=gi:4502620 /UG=Hs.1973 cyclin F /FL=gb:NM_001761.1 gb:U17105.1 NM_001761 cyclin F CCNF 899 NM_001761 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010826 // negative regulation of centrosome duplication // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204827_s_at U17105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17105.1 /DEF=Human cyclin F mRNA, complete cds. /FEA=mRNA /PROD=cyclin F /DB_XREF=gi:576780 /UG=Hs.1973 cyclin F /FL=gb:NM_001761.1 gb:U17105.1 U17105 cyclin F CCNF 899 NM_001761 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010826 // negative regulation of centrosome duplication // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204828_at NM_004584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004584.1 /DEF=Homo sapiens RAD9 (S. pombe) homolog (RAD9), mRNA. /FEA=mRNA /GEN=RAD9 /PROD=RAD9 (S. pombe) homolog /DB_XREF=gi:4759021 /UG=Hs.240457 RAD9 (S. pombe) homolog /FL=gb:U53174.1 gb:NM_004584.1 NM_004584 RAD9 homolog A (S. pombe) RAD9A 5883 NM_001243224 /// NM_004584 /// XM_006718652 /// XR_428922 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000076 // DNA replication checkpoint // traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0031573 // intra-S DNA damage checkpoint // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030896 // checkpoint clamp complex // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction 204829_s_at NM_000803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000803.2 /DEF=Homo sapiens folate receptor 2 (fetal) (FOLR2), mRNA. /FEA=mRNA /GEN=FOLR2 /PROD=folate receptor 2 precursor /DB_XREF=gi:9257218 /UG=Hs.24194 folate receptor 2 (fetal) /FL=gb:AF000380.1 gb:NM_000803.2 NM_000803 folate receptor 2 (fetal) FOLR2 2350 NM_000803 /// NM_001113534 /// NM_001113535 /// NM_001113536 /// XM_005273856 0006810 // transport // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay 0005542 // folic acid binding // inferred from direct assay /// 0008517 // folic acid transporter activity // inferred from direct assay 204830_x_at NM_002781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002781.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 5 (PSG5), mRNA. /FEA=mRNA /GEN=PSG5 /PROD=pregnancy specific beta-1-glycoprotein 5 /DB_XREF=gi:4506172 /UG=Hs.251850 pregnancy specific beta-1-glycoprotein 5 /FL=gb:M73713.1 gb:M25384.1 gb:NM_002781.1 NM_002781 pregnancy specific beta-1-glycoprotein 5 PSG5 5673 NM_001130014 /// NM_002781 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204831_at R59697 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R59697 /FEA=EST /DB_XREF=gi:830392 /DB_XREF=est:yh11b03.s1 /CLONE=IMAGE:42880 /UG=Hs.25283 cyclin-dependent kinase 8 /FL=gb:NM_001260.1 R59697 cyclin-dependent kinase 8 CDK8 1024 NM_001260 /// XM_005266215 /// XM_005266216 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204832_s_at NM_004329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004329.1 /DEF=Homo sapiens bone morphogenetic protein receptor, type IA (BMPR1A), mRNA. /FEA=mRNA /GEN=BMPR1A /PROD=bone morphogenetic protein receptor, type IAprecursor /DB_XREF=gi:4757853 /UG=Hs.2534 bone morphogenetic protein receptor, type IA /FL=gb:NM_004329.1 NM_004329 bone morphogenetic protein receptor, type IA BMPR1A 657 NM_004329 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003272 // endocardial cushion formation // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021998 // neural plate mediolateral regionalization // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048352 // paraxial mesoderm structural organization // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048382 // mesendoderm development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060896 // neural plate pattern specification // inferred from electronic annotation /// 0060914 // heart formation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204833_at NM_004707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004707.1 /DEF=Homo sapiens Apg12 (autophagy 12, S. cerevisiae)-like (APG12L), mRNA. /FEA=mRNA /GEN=APG12L /PROD=Apg12 (autophagy 12, S. cerevisiae)-like /DB_XREF=gi:4757757 /UG=Hs.264482 Apg12 (autophagy 12, S. cerevisiae)-like /FL=gb:AB017507.1 gb:NM_004707.1 NM_004707 autophagy related 12 ATG12 9140 NM_001277783 /// NM_004707 /// NR_033362 /// NR_033363 /// NR_073603 /// NR_073604 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // /// 0002376 // immune system process // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0044804 // nucleophagy // /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // 204834_at NM_006682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006682.1 /DEF=Homo sapiens fibrinogen-like 2 (FGL2), mRNA. /FEA=mRNA /GEN=FGL2 /PROD=fibrinogen-like 2 /DB_XREF=gi:5730074 /UG=Hs.2659 fibrinogen-like 2 /FL=gb:NM_006682.1 NM_006682 fibrinogen-like 2 FGL2 10875 NM_006682 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 204835_at NM_016937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016937.1 /DEF=Homo sapiens polymerase (DNA directed), alpha (POLA), mRNA. /FEA=mRNA /GEN=POLA /PROD=polymerase (DNA-directed), alpha /DB_XREF=gi:8393994 /UG=Hs.267289 polymerase (DNA directed), alpha /FL=gb:NM_016937.1 NM_016937 polymerase (DNA directed), alpha 1, catalytic subunit POLA1 5422 NM_016937 /// XM_005274552 /// XM_006724499 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000084 // mitotic S phase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006269 // DNA replication, synthesis of RNA primer // inferred from direct assay /// 0006270 // DNA replication initiation // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // inferred from mutant phenotype /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006272 // leading strand elongation // inferred from direct assay /// 0006273 // lagging strand elongation // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019985 // translesion synthesis // not recorded /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // not recorded 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005658 // alpha DNA polymerase:primase complex // inferred from direct assay /// 0005658 // alpha DNA polymerase:primase complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0001882 // nucleoside binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from mutant phenotype /// 0003896 // DNA primase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 204836_at NM_000170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000170.1 /DEF=Homo sapiens glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P) (GLDC), mRNA. /FEA=mRNA /GEN=GLDC /PROD=glycine dehydrogenase (decarboxylating; glycinedecarboxylase, glycine cleavage system protein P) /DB_XREF=gi:4504012 /UG=Hs.27 glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P) /FL=gb:M64590.1 gb:NM_000170.1 NM_000170 glycine dehydrogenase (decarboxylating) GLDC 2731 NM_000170 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006546 // glycine catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004375 // glycine dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 204837_at AL080178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080178.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K171 (from clone DKFZp434K171); partial cds. /FEA=mRNA /GEN=DKFZp434K171 /PROD=hypothetical protein /DB_XREF=gi:5262652 /UG=Hs.27194 DKFZP434K171 protein /FL=gb:NM_015458.1 AL080178 myotubularin related protein 9 MTMR9 66036 NM_015458 /// XM_005272396 0016311 // dephosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 204838_s_at NM_014381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014381.1 /DEF=Homo sapiens mutL (E. coli) homolog 3 (MLH3), mRNA. /FEA=mRNA /GEN=MLH3 /PROD=mutL (E. coli) homolog 3 /DB_XREF=gi:7657336 /UG=Hs.279843 mutL (E. coli) homolog 3 /FL=gb:AF195657.1 gb:NM_014381.1 NM_014381 mutL homolog 3 MLH3 27030 NM_001040108 /// NM_014381 /// XM_005267531 /// XM_005267532 /// XM_005267533 /// XM_005267534 /// XM_006720116 /// XM_006720117 /// XR_245681 /// XR_429311 /// XR_429312 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // non-traceable author statement /// 0007140 // male meiosis // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005712 // chiasma // not recorded /// 0032300 // mismatch repair complex // not recorded /// 0032390 // MutLbeta complex // 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // 204839_at NM_015918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015918.1 /DEF=Homo sapiens hypothetical protein (HSPC004), mRNA. /FEA=mRNA /GEN=HSPC004 /PROD=hypothetical protein /DB_XREF=gi:7705422 /UG=Hs.279913 hypothetical protein /FL=gb:AF070660.1 gb:AF117232.1 gb:NM_015918.1 NM_015918 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) POP5 51367 NM_015918 /// NM_198201 /// NM_198202 0008033 // tRNA processing // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005655 // nucleolar ribonuclease P complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 204840_s_at AI916242 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI916242 /FEA=EST /DB_XREF=gi:5636097 /DB_XREF=est:wg99b05.x1 /CLONE=IMAGE:2379345 /UG=Hs.2864 early endosome antigen 1, 162kD /FL=gb:L40157.1 gb:NM_003566.1 AI916242 early endosome antigen 1 EEA1 8411 NM_003566 /// XM_006719631 0006897 // endocytosis // inferred from mutant phenotype /// 0006906 // vesicle fusion // inferred from mutant phenotype /// 0016189 // synaptic vesicle to endosome fusion // traceable author statement /// 0045022 // early endosome to late endosome transport // non-traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005969 // serine-pyruvate aminotransferase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0030742 // GTP-dependent protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204841_s_at NM_003566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003566.1 /DEF=Homo sapiens early endosome antigen 1, 162kD (EEA1), mRNA. /FEA=mRNA /GEN=EEA1 /PROD=early endosome antigen 1, 162kD /DB_XREF=gi:4503468 /UG=Hs.2864 early endosome antigen 1, 162kD /FL=gb:L40157.1 gb:NM_003566.1 NM_003566 early endosome antigen 1 EEA1 8411 NM_003566 /// XM_006719631 0006897 // endocytosis // inferred from mutant phenotype /// 0006906 // vesicle fusion // inferred from mutant phenotype /// 0016189 // synaptic vesicle to endosome fusion // traceable author statement /// 0045022 // early endosome to late endosome transport // non-traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005969 // serine-pyruvate aminotransferase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0030742 // GTP-dependent protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204842_x_at BC002763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002763.1 /DEF=Homo sapiens, Similar to protein kinase, cAMP-dependent, regulatory, type II, alpha, clone MGC:3606, mRNA, complete cds. /FEA=mRNA /PROD=Similar to protein kinase, cAMP-dependent,regulatory, type II, alpha /DB_XREF=gi:12803842 /UG=Hs.289075 protein kinase, cAMP-dependent, regulatory, type II, alpha /FL=gb:BC002763.1 gb:NM_004157.1 BC002763 protein kinase, cAMP-dependent, regulatory, type II, alpha PRKAR2A 5576 NM_004157 /// XM_005265313 /// XM_005265314 /// XM_005265315 /// XR_427280 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 204843_s_at NM_004157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004157.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A), mRNA. /FEA=mRNA /GEN=PRKAR2A /PROD=protein kinase, cAMP-dependent, regulatory, typeII, alpha /DB_XREF=gi:4758957 /UG=Hs.289075 protein kinase, cAMP-dependent, regulatory, type II, alpha /FL=gb:BC002763.1 gb:NM_004157.1 NM_004157 protein kinase, cAMP-dependent, regulatory, type II, alpha PRKAR2A 5576 NM_004157 /// XM_005265313 /// XM_005265314 /// XM_005265315 /// XR_427280 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 204844_at L12468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12468.1 /DEF=Homo sapiens aminopeptidase A mRNA, complete cds. /FEA=mRNA /PROD=aminopeptidase A /DB_XREF=gi:347892 /UG=Hs.291 glutamyl aminopeptidase (aminopeptidase A) /FL=gb:L14721.1 gb:L12468.1 gb:NM_001977.1 L12468 glutamyl aminopeptidase (aminopeptidase A) ENPEP 2028 NM_001977 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002003 // angiotensin maturation // traceable author statement /// 0002005 // angiotensin catabolic process in blood // non-traceable author statement /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from direct assay /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008283 // cell proliferation // non-traceable author statement /// 0016477 // cell migration // inferred from direct assay /// 0032835 // glomerulus development // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from direct assay /// 0070006 // metalloaminopeptidase activity // non-traceable author statement 204845_s_at NM_001977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001977.1 /DEF=Homo sapiens glutamyl aminopeptidase (aminopeptidase A) (ENPEP), mRNA. /FEA=mRNA /GEN=ENPEP /PROD=glutamyl aminopeptidase (aminopeptidase A) /DB_XREF=gi:4503574 /UG=Hs.291 glutamyl aminopeptidase (aminopeptidase A) /FL=gb:L14721.1 gb:L12468.1 gb:NM_001977.1 NM_001977 glutamyl aminopeptidase (aminopeptidase A) ENPEP 2028 NM_001977 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002003 // angiotensin maturation // traceable author statement /// 0002005 // angiotensin catabolic process in blood // non-traceable author statement /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from direct assay /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008283 // cell proliferation // non-traceable author statement /// 0016477 // cell migration // inferred from direct assay /// 0032835 // glomerulus development // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from direct assay /// 0070006 // metalloaminopeptidase activity // non-traceable author statement 204846_at NM_000096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000096.1 /DEF=Homo sapiens ceruloplasmin (ferroxidase) (CP), mRNA. /FEA=mRNA /GEN=CP /PROD=ceruloplasmin (ferroxidase) /DB_XREF=gi:4557484 /UG=Hs.296634 ceruloplasmin (ferroxidase) /FL=gb:M13699.1 gb:NM_000096.1 NM_000096 ceruloplasmin (ferroxidase) CP 1356 NM_000096 /// NR_046371 /// XM_006713499 /// XM_006713500 /// XM_006713501 /// XM_006713502 /// XR_427361 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 204847_at NM_014415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014415.1 /DEF=Homo sapiens zinc finger protein (ZNF-U69274), mRNA. /FEA=mRNA /GEN=ZNF-U69274 /PROD=zinc finger protein /DB_XREF=gi:7657702 /UG=Hs.301956 zinc finger protein /FL=gb:U69274.1 gb:NM_014415.1 NM_014415 zinc finger and BTB domain containing 11 ZBTB11 27107 NM_014415 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204848_x_at NM_000559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000559.1 /DEF=Homo sapiens hemoglobin, gamma A (HBG1), mRNA. /FEA=mRNA /GEN=HBG1 /PROD=hemoglobin, gamma A /DB_XREF=gi:4504352 /UG=Hs.305960 hemoglobin, gamma A /FL=gb:AF130098.1 gb:NM_000559.1 NM_000559 hemoglobin, gamma A /// hemoglobin, gamma G HBG1 /// HBG2 3047 /// 3048 NM_000184 /// NM_000559 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204849_at NM_006602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006602.1 /DEF=Homo sapiens transcription factor-like 5 (basic helix-loop-helix) (TCFL5), mRNA. /FEA=mRNA /GEN=TCFL5 /PROD=transcription factor-like 5 (basichelix-loop-helix) /DB_XREF=gi:5730082 /UG=Hs.30696 transcription factor-like 5 (basic helix-loop-helix) /FL=gb:AB012124.1 gb:NM_006602.1 gb:AF070992.1 NM_006602 transcription factor-like 5 (basic helix-loop-helix) TCFL5 10732 NM_006602 /// XM_005260184 /// XM_005260185 /// XM_005260186 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from expression pattern /// 0045595 // regulation of cell differentiation // inferred from expression pattern 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 204850_s_at NM_000555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000555.1 /DEF=Homo sapiens doublecortex; lissencephaly, X-linked (doublecortin) (DCX), mRNA. /FEA=mRNA /GEN=DCX /PROD=doublecortex; lissencephaly, X-linked(doublecortin) /DB_XREF=gi:10835124 /UG=Hs.34780 doublecortex; lissencephaly, X-linked (doublecortin) /FL=gb:NM_000555.1 gb:AF040255.1 gb:AF040254.1 NM_000555 doublecortin DCX 1641 NM_000555 /// NM_001195553 /// NM_178151 /// NM_178152 /// NM_178153 /// XM_005262091 0001764 // neuron migration // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction 204851_s_at AF040254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040254.1 /DEF=Homo sapiens doublecortin isoform (DCX) mRNA, complete cds. /FEA=mRNA /GEN=DCX /PROD=doublecortin isoform /DB_XREF=gi:2792349 /UG=Hs.34780 doublecortex; lissencephaly, X-linked (doublecortin) /FL=gb:NM_000555.1 gb:AF040255.1 gb:AF040254.1 AF040254 doublecortin DCX 1641 NM_000555 /// NM_001195553 /// NM_178151 /// NM_178152 /// NM_178153 /// XM_005262091 0001764 // neuron migration // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction 204852_s_at NM_002832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002832.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), mRNA. /FEA=mRNA /GEN=PTPN7 /PROD=protein tyrosine phosphatase, non-receptor type7 /DB_XREF=gi:4506298 /UG=Hs.35 protein tyrosine phosphatase, non-receptor type 7 /FL=gb:BC001746.1 gb:M64322.1 gb:NM_002832.1 NM_002832 protein tyrosine phosphatase, non-receptor type 7 PTPN7 5778 NM_001199797 /// NM_002832 /// NM_080588 /// NM_080589 /// NR_037663 /// NR_037664 /// XR_426791 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 204853_at NM_006190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006190.1 /DEF=Homo sapiens origin recognition complex, subunit 2 (yeast homolog)-like (ORC2L), mRNA. /FEA=mRNA /GEN=ORC2L /PROD=origin recognition complex, subunit 2 (yeasthomolog)-like /DB_XREF=gi:5453829 /UG=Hs.41694 origin recognition complex, subunit 2 (yeast homolog)-like /FL=gb:U27459.1 gb:U40268.2 gb:NM_006190.1 NM_006190 origin recognition complex, subunit 2 ORC2 4999 NM_006190 /// NR_033915 /// XM_006712555 /// XR_427088 /// XR_427089 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0000808 // origin recognition complex // inferred from direct assay /// 0000939 // condensed chromosome inner kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003688 // DNA replication origin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204854_at NM_014262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014262.1 /DEF=Homo sapiens hypothetical protein B (HSU47926), mRNA. /FEA=mRNA /GEN=HSU47926 /PROD=hypothetical protein B /DB_XREF=gi:7657207 /UG=Hs.46458 hypothetical protein B /FL=gb:U47926.1 gb:NM_014262.1 NM_014262 leprecan-like 2 LEPREL2 10536 NM_014262 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0019797 // procollagen-proline 3-dioxygenase activity // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 204855_at NM_002639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002639.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 (SERPINB5), mRNA. /FEA=mRNA /GEN=SERPINB5 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 5 /DB_XREF=gi:4505788 /UG=Hs.55279 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 /FL=gb:NM_002639.1 gb:U04313.1 NM_002639 serpin peptidase inhibitor, clade B (ovalbumin), member 5 SERPINB5 5268 NM_002639 /// XM_006722483 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 204856_at NM_014256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014256.1 /DEF=Homo sapiens transmembrane protein 3 (TMEM3), mRNA. /FEA=mRNA /GEN=TMEM3 /PROD=transmembrane protein 3 /DB_XREF=gi:7657171 /UG=Hs.69009 transmembrane protein 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3 /FL=gb:AB049585.1 gb:AB015630.1 gb:NM_014256.1 NM_014256 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 B3GNT3 10331 NM_014256 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047223 // beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity // inferred from electronic annotation 204857_at NM_003550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003550.1 /DEF=Homo sapiens MAD1 (mitotic arrest deficient, yeast, homolog)-like 1 (MAD1L1), mRNA. /FEA=mRNA /GEN=MAD1L1 /PROD=MAD1-like 1 /DB_XREF=gi:4505064 /UG=Hs.7345 MAD1 (mitotic arrest deficient, yeast, homolog)-like 1 /FL=gb:U33822.1 gb:AF123318.1 gb:NM_003550.1 gb:AF083811.1 NM_003550 MAD1 mitotic arrest deficient-like 1 (yeast) MAD1L1 8379 NM_001013836 /// NM_001013837 /// NM_003550 /// XM_005249876 /// XM_005249877 /// XM_005249878 /// XM_006715788 0000089 // mitotic metaphase // non-traceable author statement /// 0000090 // mitotic anaphase // non-traceable author statement /// 0000093 // mitotic telophase // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0090235 // regulation of metaphase plate congression // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204858_s_at NM_001953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001953.2 /DEF=Homo sapiens endothelial cell growth factor 1 (platelet-derived) (ECGF1), mRNA. /FEA=mRNA /GEN=ECGF1 /PROD=endothelial cell growth factor 1(platelet-derived) /DB_XREF=gi:7669488 /UG=Hs.73946 endothelial cell growth factor 1 (platelet-derived) /FL=gb:NM_001953.2 NM_001953 thymidine phosphorylase TYMP 1890 NM_001113755 /// NM_001113756 /// NM_001257988 /// NM_001257989 /// NM_001953 0000002 // mitochondrial genome maintenance // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // inferred from electronic annotation /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030016 // myofibril // inferred from direct assay 0004645 // phosphorylase activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0009032 // thymidine phosphorylase activity // inferred from electronic annotation /// 0016154 // pyrimidine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 204859_s_at NM_013229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013229.1 /DEF=Homo sapiens apoptotic protease activating factor (APAF1), transcript variant 1, mRNA. /FEA=mRNA /GEN=APAF1 /PROD=apoptotic protease activating factor isoform a /DB_XREF=gi:7108332 /UG=Hs.77579 apoptotic protease activating factor /FL=gb:AB007873.1 gb:AF134397.1 gb:NM_013229.1 NM_013229 apoptotic peptidase activating factor 1 APAF1 317 NM_001160 /// NM_013229 /// NM_181861 /// NM_181868 /// NM_181869 /// XR_429095 0001843 // neural tube closure // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from direct assay /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0072432 // response to G1 DNA damage checkpoint signaling // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay /// 0043293 // apoptosome // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation 204860_s_at AI817801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817801 /FEA=EST /DB_XREF=gi:5436880 /DB_XREF=est:wk40d12.x1 /CLONE=IMAGE:2417879 /UG=Hs.79019 baculoviral IAP repeat-containing 1 /FL=gb:U19251.1 gb:NM_004536.1 AI817801 NLR family, apoptosis inhibitory protein NAIP 4671 NM_004536 /// NM_022892 /// XM_005248523 /// XM_005248524 /// XM_005276800 /// XM_005276801 /// XM_005276802 /// XM_006714626 /// XM_006714627 /// XM_006714628 /// XM_006714629 /// XM_006714630 /// XM_006725453 /// XM_006725454 /// XM_006725455 /// XM_006725456 /// XM_006725457 /// XM_006725458 /// XM_006725459 /// XM_006726218 /// XM_006726219 /// XM_006726220 /// XM_006726221 /// XM_006726222 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204861_s_at NM_004536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004536.1 /DEF=Homo sapiens baculoviral IAP repeat-containing 1 (BIRC1), mRNA. /FEA=mRNA /GEN=BIRC1 /PROD=baculoviral IAP repeat-containing 1 /DB_XREF=gi:4758751 /UG=Hs.79019 baculoviral IAP repeat-containing 1 /FL=gb:U19251.1 gb:NM_004536.1 NM_004536 NLR family, apoptosis inhibitory protein NAIP 4671 NM_004536 /// NM_022892 /// XM_005248523 /// XM_005248524 /// XM_005276800 /// XM_005276801 /// XM_005276802 /// XM_006714626 /// XM_006714627 /// XM_006714628 /// XM_006714629 /// XM_006714630 /// XM_006725453 /// XM_006725454 /// XM_006725455 /// XM_006725456 /// XM_006725457 /// XM_006725458 /// XM_006725459 /// XM_006726218 /// XM_006726219 /// XM_006726220 /// XM_006726221 /// XM_006726222 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204862_s_at NM_002513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002513.1 /DEF=Homo sapiens non-metastatic cells 3, protein expressed in (NME3), mRNA. /FEA=mRNA /GEN=NME3 /PROD=non-metastatic cells 3, protein expressed in /DB_XREF=gi:4505410 /UG=Hs.81687 non-metastatic cells 3, protein expressed in /FL=gb:U29656.1 gb:BC000250.1 gb:NM_002513.1 NM_002513 NME/NM23 nucleoside diphosphate kinase 3 NME3 4832 NM_002513 /// XM_005255332 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204863_s_at BE856546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856546 /FEA=EST /DB_XREF=gi:10369675 /DB_XREF=est:7f64a11.x1 /CLONE=IMAGE:3299420 /UG=Hs.82065 interleukin 6 signal transducer (gp130, oncostatin M receptor) /FL=gb:M57230.1 gb:NM_002184.1 BE856546 interleukin 6 signal transducer IL6ST 3572 NM_001190981 /// NM_002184 /// NM_175767 /// NR_120480 /// XM_005248496 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0002821 // positive regulation of adaptive immune response // inferred by curator /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038154 // interleukin-11-mediated signaling pathway // inferred from electronic annotation /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from genetic interaction /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070106 // interleukin-27-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070110 // ciliary neurotrophic factor receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from genetic interaction /// 0004921 // interleukin-11 receptor activity // inferred from electronic annotation /// 0004923 // leukemia inhibitory factor receptor activity // inferred from genetic interaction /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019970 // interleukin-11 binding // inferred from electronic annotation /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred by curator 204864_s_at NM_002184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002184.1 /DEF=Homo sapiens interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST), mRNA. /FEA=mRNA /GEN=IL6ST /PROD=interleukin 6 signal transducer (gp130,oncostatin M receptor) /DB_XREF=gi:4504674 /UG=Hs.82065 interleukin 6 signal transducer (gp130, oncostatin M receptor) /FL=gb:M57230.1 gb:NM_002184.1 NM_002184 interleukin 6 signal transducer IL6ST 3572 NM_001190981 /// NM_002184 /// NM_175767 /// NR_120480 /// XM_005248496 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0002821 // positive regulation of adaptive immune response // inferred by curator /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038154 // interleukin-11-mediated signaling pathway // inferred from electronic annotation /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from genetic interaction /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070106 // interleukin-27-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070110 // ciliary neurotrophic factor receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from genetic interaction /// 0004921 // interleukin-11 receptor activity // inferred from electronic annotation /// 0004923 // leukemia inhibitory factor receptor activity // inferred from genetic interaction /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019970 // interleukin-11 binding // inferred from electronic annotation /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred by curator 204865_at NM_005181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005181.2 /DEF=Homo sapiens carbonic anhydrase III, muscle specific (CA3), mRNA. /FEA=mRNA /GEN=CA3 /PROD=carbonic anhydrase III /DB_XREF=gi:6996001 /UG=Hs.82129 carbonic anhydrase III, muscle specific /FL=gb:BC004897.1 gb:NM_005181.2 NM_005181 carbonic anhydrase III, muscle specific CA3 761 NM_005181 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204866_at NM_014735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014735.1 /DEF=Homo sapiens KIAA0215 gene product (KIAA0215), mRNA. /FEA=mRNA /GEN=KIAA0215 /PROD=KIAA0215 gene product /DB_XREF=gi:7662005 /UG=Hs.82292 KIAA0215 gene product /FL=gb:D86969.1 gb:NM_014735.1 NM_014735 jade family PHD finger 3 JADE3 9767 NM_001077445 /// NM_014735 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204867_at NM_005258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005258.2 /DEF=Homo sapiens GTP cyclohydrolase I feedback regulatory protein (GCHFR), mRNA. /FEA=mRNA /GEN=GCHFR /PROD=GTP cyclohydrolase I feedback regulatoryprotein /DB_XREF=gi:6382072 /UG=Hs.83081 GTP cyclohydrolase I feedback regulatory protein /FL=gb:NM_005258.2 NM_005258 GTP cyclohydrolase I feedback regulator GCHFR 2644 NM_005258 0006461 // protein complex assembly // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009890 // negative regulation of biosynthetic process // inferred from electronic annotation /// 0042133 // neurotransmitter metabolic process // traceable author statement /// 0043105 // negative regulation of GTP cyclohydrolase I activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0044549 // GTP cyclohydrolase binding // inferred from electronic annotation 204868_at NM_001545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001545.1 /DEF=Homo sapiens immature colon carcinoma transcript 1 (ICT1), mRNA. /FEA=mRNA /GEN=ICT1 /PROD=immature colon carcinoma transcript 1 /DB_XREF=gi:4557656 /UG=Hs.9078 immature colon carcinoma transcript 1 /FL=gb:NM_001545.1 NM_001545 immature colon carcinoma transcript 1 ICT1 3396 NM_001545 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation /// 0070126 // mitochondrial translational termination // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay 0003747 // translation release factor activity // inferred from electronic annotation /// 0004045 // aminoacyl-tRNA hydrolase activity // inferred from direct assay /// 0016150 // translation release factor activity, codon nonspecific // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 204869_at AL031664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031664 /DEF=Human DNA sequence from clone RP4-531H16 on chromosome 20p11.22-12. Contains the 3 part of the PCSK2 gene for proprotein convertase subtilisinkexin type 2 (Neuroendocrine Convertase 2, EC 3.4.21.94, NEC-2, KEX2-like endoprotease 2), a pseudogene... /FEA=mRNA_2 /DB_XREF=gi:4375975 /UG=Hs.93164 proprotein convertase subtilisinkexin type 2 /FL=gb:J05252.1 gb:NM_002594.1 AL031664 proprotein convertase subtilisin/kexin type 2 PCSK2 5126 NM_001201528 /// NM_001201529 /// NM_002594 0006508 // proteolysis // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0030070 // insulin processing // inferred from direct assay /// 0034230 // enkephalin processing // inferred from sequence or structural similarity /// 0034231 // islet amyloid polypeptide processing // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 204870_s_at NM_002594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002594.1 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 2 (PCSK2), mRNA. /FEA=mRNA /GEN=PCSK2 /PROD=proprotein convertase subtilisinkexin type 2 /DB_XREF=gi:4505646 /UG=Hs.93164 proprotein convertase subtilisinkexin type 2 /FL=gb:J05252.1 gb:NM_002594.1 NM_002594 proprotein convertase subtilisin/kexin type 2 PCSK2 5126 NM_001201528 /// NM_001201529 /// NM_002594 0006508 // proteolysis // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0030070 // insulin processing // inferred from direct assay /// 0034230 // enkephalin processing // inferred from sequence or structural similarity /// 0034231 // islet amyloid polypeptide processing // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 204871_at NM_006980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006980.1 /DEF=Homo sapiens transcription termination factor, mitochondrial (MTERF), mRNA. /FEA=mRNA /GEN=MTERF /PROD=transcription termination factor, mitochondrial /DB_XREF=gi:5902009 /UG=Hs.97996 transcription termination factor, mitochondrial /FL=gb:BC000965.2 gb:NM_006980.1 NM_006980 mitochondrial transcription termination factor 1 MTERF1 7978 NM_006980 /// XM_005250593 /// XM_005250594 /// XM_005250595 /// XM_006716126 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006393 // termination of mitochondrial transcription // inferred from direct assay /// 0006393 // termination of mitochondrial transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032392 // DNA geometric change // inferred from direct assay 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204872_at NM_007005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007005.1 /DEF=Homo sapiens BCE-1 protein (BCE-1), mRNA. /FEA=mRNA /GEN=BCE-1 /PROD=BCE-1 protein /DB_XREF=gi:5921462 /UG=Hs.99824 BCE-1 protein /FL=gb:AF068197.1 gb:NM_007005.1 NM_007005 transducin-like enhancer of split 4 TLE4 7091 NM_001282748 /// NM_001282749 /// NM_001282753 /// NM_001282760 /// NM_007005 /// NR_104239 /// XM_005252167 /// XM_005252169 /// XM_005252173 /// XM_005252174 /// XM_005252175 /// XM_005252177 /// XM_006717264 /// XM_006717265 /// XM_006717266 /// XM_006717267 /// XM_006717268 /// XM_006717269 /// XM_006717270 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 204873_at NM_000466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000466.1 /DEF=Homo sapiens peroxisome biogenesis factor 1 (PEX1), mRNA. /FEA=mRNA /GEN=PEX1 /PROD=peroxisome biogenesis factor 1 /DB_XREF=gi:4505724 /UG=Hs.99847 peroxisome biogenesis factor 1 /FL=gb:AF026086.1 gb:AF030356.1 gb:NM_000466.1 gb:AB008112.1 NM_000466 peroxisomal biogenesis factor 1 PEX1 5189 NM_000466 /// NM_001282677 /// NM_001282678 /// XM_005250429 /// XM_005250433 /// XR_242246 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0060152 // microtubule-based peroxisome localization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from mutant phenotype 204874_x_at NM_003933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003933.2 /DEF=Homo sapiens BAI1-associated protein 3 (BAIAP3), mRNA. /FEA=mRNA /GEN=BAIAP3 /PROD=BAI1-associated protein 3 /DB_XREF=gi:4809280 /UG=Hs.101516 BAI1-associated protein 3 /FL=gb:NM_003933.2 NM_003933 BAI1-associated protein 3 BAIAP3 8938 NM_001199096 /// NM_001199097 /// NM_001199098 /// NM_001199099 /// NM_001286464 /// NM_003933 0007186 // G-protein coupled receptor signaling pathway // inferred from physical interaction /// 0007269 // neurotransmitter secretion // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement 204875_s_at NM_001500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001500.1 /DEF=Homo sapiens GDP-mannose 4,6-dehydratase (GMDS), mRNA. /FEA=mRNA /GEN=GMDS /PROD=GDP-mannose 4,6-dehydratase /DB_XREF=gi:4504030 /UG=Hs.105435 GDP-mannose 4,6-dehydratase /FL=gb:BC000117.1 gb:AF042377.1 gb:NM_001500.1 NM_001500 GDP-mannose 4,6-dehydratase GMDS 2762 NM_001253846 /// NM_001500 /// XM_006715066 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0019673 // GDP-mannose metabolic process // inferred from direct assay /// 0019673 // GDP-mannose metabolic process // inferred from genetic interaction /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from direct assay /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008446 // GDP-mannose 4,6-dehydratase activity // inferred from direct assay /// 0008446 // GDP-mannose 4,6-dehydratase activity // inferred from genetic interaction /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0070401 // NADP+ binding // inferred from direct assay 204876_at NM_014699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014699.1 /DEF=Homo sapiens KIAA0296 gene product (KIAA0296), mRNA. /FEA=mRNA /GEN=KIAA0296 /PROD=KIAA0296 gene product /DB_XREF=gi:7662043 /UG=Hs.119273 KIAA0296 gene product /FL=gb:AB002294.1 gb:NM_014699.1 NM_014699 zinc finger protein 646 ZNF646 9726 NM_014699 /// XM_005255710 /// XM_005255711 /// XM_005255712 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204877_s_at AW007163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007163 /FEA=EST /DB_XREF=gi:5855941 /DB_XREF=est:ws50a03.x1 /CLONE=IMAGE:2500588 /UG=Hs.122823 thousand and one amino acid protein kinase /FL=gb:AB020688.1 gb:NM_004783.1 AW007163 TAO kinase 2 TAOK2 9344 NM_001252043 /// NM_004783 /// NM_016151 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction 204878_s_at NM_004783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004783.1 /DEF=Homo sapiens thousand and one amino acid protein kinase (TAO1), mRNA. /FEA=mRNA /GEN=TAO1 /PROD=thousand and one amino acid protein kinase /DB_XREF=gi:4759207 /UG=Hs.122823 thousand and one amino acid protein kinase /FL=gb:AB020688.1 gb:NM_004783.1 NM_004783 TAO kinase 2 TAOK2 9344 NM_001252043 /// NM_004783 /// NM_016151 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction 204879_at NM_006474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006474.1 /DEF=Homo sapiens lung type-I cell membrane-associated glycoprotein (T1A-2), transcript variant 2, mRNA. /FEA=mRNA /GEN=T1A-2 /PROD=lung type-I cell membrane-associatedglycoprotein, isoform 2 precursor /DB_XREF=gi:5454097 /UG=Hs.135150 lung type-I cell membrane-associated glycoprotein /FL=gb:AF030428.1 gb:NM_006474.1 NM_006474 podoplanin PDPN 10630 NM_001006624 /// NM_001006625 /// NM_006474 /// NM_198389 /// XM_006710295 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006833 // water transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from sequence or structural similarity /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010572 // positive regulation of platelet activation // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0001726 // ruffle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005372 // water transmembrane transporter activity // inferred from sequence or structural similarity /// 0008517 // folic acid transporter activity // inferred from sequence or structural similarity /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015250 // water channel activity // inferred from sequence or structural similarity 204880_at NM_002412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002412.1 /DEF=Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. /FEA=mRNA /GEN=MGMT /PROD=O-6-methylguanine-DNA methyltransferase /DB_XREF=gi:4505176 /UG=Hs.1384 O-6-methylguanine-DNA methyltransferase /FL=gb:BC000824.1 gb:M31767.1 gb:M60761.1 gb:M29971.1 gb:NM_002412.1 NM_002412 O-6-methylguanine-DNA methyltransferase MGMT 4255 NM_002412 /// XM_005252682 /// XM_006717863 0006266 // DNA ligation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006307 // DNA dealkylation involved in DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003908 // methylated-DNA-[protein]-cysteine S-methyltransferase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // traceable author statement /// 0009008 // DNA-methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204881_s_at NM_003358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003358.1 /DEF=Homo sapiens UDP-glucose ceramide glucosyltransferase (UGCG), mRNA. /FEA=mRNA /GEN=UGCG /PROD=ceramide glucosyltransferase /DB_XREF=gi:4507810 /UG=Hs.152601 UDP-glucose ceramide glucosyltransferase /FL=gb:D50840.1 gb:NM_003358.1 NM_003358 UDP-glucose ceramide glucosyltransferase UGCG 7357 NM_003358 /// XM_005252186 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006679 // glucosylceramide biosynthetic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008120 // ceramide glucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 204882_at NM_014882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014882.1 /DEF=Homo sapiens KIAA0053 gene product (KIAA0053), mRNA. /FEA=mRNA /GEN=KIAA0053 /PROD=KIAA0053 gene product /DB_XREF=gi:7661881 /UG=Hs.1528 KIAA0053 gene product /FL=gb:D29642.1 gb:NM_014882.1 NM_014882 Rho GTPase activating protein 25 ARHGAP25 9938 NM_001007231 /// NM_001166276 /// NM_001166277 /// NM_014882 /// XM_005264675 /// XM_005264676 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 204883_s_at AI968626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI968626 /FEA=EST /DB_XREF=gi:5765444 /DB_XREF=est:wt90g10.x1 /CLONE=IMAGE:2514786 /UG=Hs.152983 HUS1 (S. pombe) checkpoint homolog /FL=gb:AF076844.1 gb:AF110393.1 gb:NM_004507.1 AI968626 HUS1 checkpoint homolog (S. pombe) HUS1 3364 NM_004507 /// NR_037917 /// XR_428079 /// XR_428080 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204884_s_at NM_004507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004507.1 /DEF=Homo sapiens HUS1 (S. pombe) checkpoint homolog (HUS1), mRNA. /FEA=mRNA /GEN=HUS1 /PROD=HUS1 (S. pombe) checkpoint homolog /DB_XREF=gi:4758575 /UG=Hs.152983 HUS1 (S. pombe) checkpoint homolog /FL=gb:AF076844.1 gb:AF110393.1 gb:NM_004507.1 NM_004507 HUS1 checkpoint homolog (S. pombe) HUS1 3364 NM_004507 /// NR_037917 /// XR_428079 /// XR_428080 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204885_s_at NM_005823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005823.2 /DEF=Homo sapiens mesothelin (MSLN), transcript variant 1, mRNA. /FEA=mRNA /GEN=MSLN /PROD=megakaryocyte potentiating factor precursor /DB_XREF=gi:7108357 /UG=Hs.155981 mesothelin /FL=gb:D49441.1 gb:BC003512.1 gb:NM_005823.2 NM_005823 mesothelin MSLN 10232 NM_001177355 /// NM_005823 /// NM_013404 /// XM_005255034 /// XM_006720836 /// XM_006720837 0007155 // cell adhesion // non-traceable author statement /// 0031016 // pancreas development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204886_at AL043646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043646 /FEA=EST /DB_XREF=gi:5423033 /DB_XREF=est:DKFZp434I2227_s1 /CLONE=DKFZp434I2227 /UG=Hs.172052 serinethreonine kinase 18 /FL=gb:NM_014264.1 AL043646 polo-like kinase 4 PLK4 10733 NM_001190799 /// NM_001190801 /// NM_014264 /// XM_005262701 /// XM_006714071 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046601 // positive regulation of centriole replication // inferred from mutant phenotype /// 0060707 // trophoblast giant cell differentiation // inferred from sequence or structural similarity /// 0098535 // de novo centriole assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0098536 // deuterosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204887_s_at NM_014264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014264.1 /DEF=Homo sapiens serinethreonine kinase 18 (STK18), mRNA. /FEA=mRNA /GEN=STK18 /PROD=serinethreonine kinase 18 /DB_XREF=gi:7657626 /UG=Hs.172052 serinethreonine kinase 18 /FL=gb:NM_014264.1 NM_014264 polo-like kinase 4 PLK4 10733 NM_001190799 /// NM_001190801 /// NM_014264 /// XM_005262701 /// XM_006714071 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046601 // positive regulation of centriole replication // inferred from mutant phenotype /// 0060707 // trophoblast giant cell differentiation // inferred from sequence or structural similarity /// 0098535 // de novo centriole assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0098536 // deuterosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204888_s_at AA772093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA772093 /FEA=EST /DB_XREF=gi:2823876 /DB_XREF=est:ai41h12.s1 /CLONE=1359623 /UG=Hs.172700 neuralized (Drosophila)-like /FL=gb:U87864.1 gb:AF029729.1 gb:NM_004210.1 AA772093 neuralized E3 ubiquitin protein ligase 1 NEURL1 9148 NM_004210 /// XM_005270269 /// XM_005270270 0006417 // regulation of translation // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0060999 // positive regulation of dendritic spine development // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0045183 // translation factor activity, non-nucleic acid binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 204889_s_at AF029729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029729.1 /DEF=Homo sapiens neuralized mRNA, complete cds. /FEA=mRNA /PROD=neuralized /DB_XREF=gi:4103927 /UG=Hs.172700 neuralized (Drosophila)-like /FL=gb:U87864.1 gb:AF029729.1 gb:NM_004210.1 AF029729 neuralized E3 ubiquitin protein ligase 1 NEURL1 9148 NM_004210 /// XM_005270269 /// XM_005270270 0006417 // regulation of translation // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0060999 // positive regulation of dendritic spine development // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0045183 // translation factor activity, non-nucleic acid binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 204890_s_at U07236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U07236.1 /DEF=Human mutant lymphocyte-specific protein tyrosine kinase (LCK) mRNA, complete cds. /FEA=mRNA /GEN=LCK /PROD=lymphocyte-specific protein tyrosine kinase /DB_XREF=gi:460965 /UG=Hs.1765 lymphocyte-specific protein tyrosine kinase /FL=gb:M36881.1 gb:U07236.1 gb:NM_005356.1 U07236 LCK proto-oncogene, Src family tyrosine kinase LCK 3932 NM_001042771 /// NM_005356 /// XM_005270862 /// XM_005270863 /// XM_005270864 0006468 // protein phosphorylation // inferred from direct assay /// 0006882 // cellular zinc ion homeostasis // inferred from expression pattern /// 0006882 // cellular zinc ion homeostasis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030217 // T cell differentiation // inferred from mutant phenotype /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // non-traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051249 // regulation of lymphocyte activation // non-traceable author statement /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000242 // pericentriolar material // inferred from direct assay /// 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0001772 // immunological synapse // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0042609 // CD4 receptor binding // inferred from physical interaction /// 0042610 // CD8 receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 204891_s_at NM_005356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005356.1 /DEF=Homo sapiens lymphocyte-specific protein tyrosine kinase (LCK), mRNA. /FEA=mRNA /GEN=LCK /PROD=lymphocyte-specific protein tyrosine kinase /DB_XREF=gi:4885448 /UG=Hs.1765 lymphocyte-specific protein tyrosine kinase /FL=gb:M36881.1 gb:U07236.1 gb:NM_005356.1 NM_005356 LCK proto-oncogene, Src family tyrosine kinase LCK 3932 NM_001042771 /// NM_005356 /// XM_005270862 /// XM_005270863 /// XM_005270864 0006468 // protein phosphorylation // inferred from direct assay /// 0006882 // cellular zinc ion homeostasis // inferred from expression pattern /// 0006882 // cellular zinc ion homeostasis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030217 // T cell differentiation // inferred from mutant phenotype /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // non-traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051249 // regulation of lymphocyte activation // non-traceable author statement /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000242 // pericentriolar material // inferred from direct assay /// 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0001772 // immunological synapse // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0042609 // CD4 receptor binding // inferred from physical interaction /// 0042610 // CD8 receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 204892_x_at NM_001402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001402.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA. /FEA=mRNA /GEN=EEF1A1 /PROD=eukaryotic translation elongation factor 1 alpha1 /DB_XREF=gi:4503470 /UG=Hs.181165 eukaryotic translation elongation factor 1 alpha 1 /FL=gb:AF267861.1 gb:NM_001402.1 NM_001402 eukaryotic translation elongation factor 1 alpha 1 EEF1A1 1915 NM_001402 /// NM_001403 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204893_s_at NM_004799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004799.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog interacting protein, receptor activation anchor (MADHIP), transcript variant 3, mRNA. /FEA=mRNA /GEN=MADHIP /PROD=Smad anchor for receptor activation, isoform 3 /DB_XREF=gi:4759059 /UG=Hs.194716 MAD (mothers against decapentaplegic, Drosophila) homolog interacting protein, receptor activation anchor /FL=gb:AF104304.1 gb:NM_004799.1 NM_004799 zinc finger, FYVE domain containing 9 ZFYVE9 9372 NM_004799 /// NM_007323 /// NM_007324 0006508 // proteolysis // non-traceable author statement /// 0006897 // endocytosis // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008236 // serine-type peptidase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204894_s_at NM_003734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003734.2 /DEF=Homo sapiens amine oxidase, copper containing 3 (vascular adhesion protein 1) (AOC3), mRNA. /FEA=mRNA /GEN=AOC3 /PROD=copper containing amine oxidase 3 precursor /DB_XREF=gi:6806883 /UG=Hs.198241 amine oxidase, copper containing 3 (vascular adhesion protein 1) /FL=gb:U39447.1 gb:AF067406.1 gb:NM_003734.2 NM_003734 amine oxidase, copper containing 3 AOC3 8639 NM_001277731 /// NM_001277732 /// NM_003734 /// NR_102422 0006812 // cation transport // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0009308 // amine metabolic process // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005261 // cation channel activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008131 // primary amine oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048038 // quinone binding // inferred from direct assay /// 0052593 // tryptamine:oxygen oxidoreductase (deaminating) activity // inferred from electronic annotation /// 0052594 // aminoacetone:oxygen oxidoreductase(deaminating) activity // inferred from electronic annotation /// 0052595 // aliphatic-amine oxidase activity // inferred from electronic annotation /// 0052596 // phenethylamine:oxygen oxidoreductase (deaminating) activity // inferred from electronic annotation 204895_x_at NM_004532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004532.1 /DEF=Homo sapiens mucin 4, tracheobronchial (MUC4), mRNA. /FEA=mRNA /GEN=MUC4 /PROD=mucin 4, tracheobronchial /DB_XREF=gi:11034812 /UG=Hs.198267 mucin 4, tracheobronchial /FL=gb:NM_004532.1 gb:NM_018406.1 NM_004532 mucin 4, cell surface associated MUC4 4585 NM_004532 /// NM_018406 /// NM_138297 /// NM_138298 /// NM_138299 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005176 // ErbB-2 class receptor binding // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 204896_s_at AI675173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI675173 /FEA=EST /DB_XREF=gi:4875653 /DB_XREF=est:tm80g01.x1 /CLONE=IMAGE:2164464 /UG=Hs.199248 prostaglandin E receptor 4 (subtype EP4) /FL=gb:D28472.1 gb:L25124.1 gb:NM_000958.1 gb:L28175.1 AI675173 prostaglandin E receptor 4 (subtype EP4) PTGER4 5734 NM_000958 /// XM_005248326 /// XM_005248327 0006955 // immune response // inferred from expression pattern /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033624 // negative regulation of integrin activation // inferred from direct assay /// 0042093 // T-helper cell differentiation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 2000420 // negative regulation of eosinophil extravasation // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204897_at AA897516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA897516 /FEA=EST /DB_XREF=gi:3034136 /DB_XREF=est:aj62c04.s1 /CLONE=IMAGE:1394886 /UG=Hs.199248 prostaglandin E receptor 4 (subtype EP4) /FL=gb:D28472.1 gb:L25124.1 gb:NM_000958.1 gb:L28175.1 AA897516 prostaglandin E receptor 4 (subtype EP4) PTGER4 5734 NM_000958 /// XM_005248326 /// XM_005248327 0006955 // immune response // inferred from expression pattern /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033624 // negative regulation of integrin activation // inferred from direct assay /// 0042093 // T-helper cell differentiation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 2000420 // negative regulation of eosinophil extravasation // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204898_at AF055993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055993.1 /DEF=Homo sapiens mSin3A associated polypeptide p30 mRNA, complete cds. /FEA=mRNA /PROD=mSin3A associated polypeptide p30 /DB_XREF=gi:3493210 /UG=Hs.20985 sin3-associated polypeptide, 30kD /FL=gb:AF055993.1 gb:NM_003864.1 AF055993 Sin3A-associated protein, 30kDa SAP30 8819 NM_003864 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204899_s_at BF247098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF247098 /FEA=EST /DB_XREF=gi:11162171 /DB_XREF=est:601854541F1 /CLONE=IMAGE:4074154 /UG=Hs.20985 sin3-associated polypeptide, 30kD /FL=gb:AF055993.1 gb:NM_003864.1 BF247098 Sin3A-associated protein, 30kDa SAP30 8819 NM_003864 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204900_x_at NM_003864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003864.1 /DEF=Homo sapiens sin3-associated polypeptide, 30kD (SAP30), mRNA. /FEA=mRNA /GEN=SAP30 /PROD=sin3 associated polypeptide p30 /DB_XREF=gi:4506782 /UG=Hs.20985 sin3-associated polypeptide, 30kD /FL=gb:AF055993.1 gb:NM_003864.1 NM_003864 Sin3A-associated protein, 30kDa SAP30 8819 NM_003864 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204901_at AA824369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA824369 /FEA=EST /DB_XREF=gi:2896253 /DB_XREF=est:aj29a05.s1 /CLONE=1391696 /UG=Hs.226434 beta-transducin repeat containing /FL=gb:NM_003939.1 gb:AF129530.1 AA824369 beta-transducin repeat containing E3 ubiquitin protein ligase BTRC 8945 NM_001256856 /// NM_003939 /// NM_033637 /// XM_005270264 /// XM_006718054 /// XR_428727 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from direct assay /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 204902_s_at NM_013325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013325.1 /DEF=Homo sapiens KIAA0943 protein (KIAA0943), mRNA. /FEA=mRNA /GEN=KIAA0943 /PROD=hypothetical protein /DB_XREF=gi:10835257 /UG=Hs.272586 KIAA0943 protein /FL=gb:NM_013325.1 gb:BC000719.1 gb:AL050288.1 gb:AL080168.1 NM_013325 autophagy related 4B, cysteine peptidase ATG4B 23192 NM_013325 /// NM_178326 /// XM_005246992 /// XM_005246993 /// XM_005246995 /// XM_005246996 /// XM_006712371 0000045 // autophagic vacuole assembly // inferred from genetic interaction /// 0000422 // mitochondrion degradation // not recorded /// 0006501 // C-terminal protein lipidation // not recorded /// 0006508 // proteolysis // inferred from direct assay /// 0006612 // protein targeting to membrane // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0051697 // protein delipidation // not recorded 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 204903_x_at AL080168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080168.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C151 (from clone DKFZp434C151); complete cds. /FEA=mRNA /GEN=DKFZp434C151 /PROD=hypothetical protein /DB_XREF=gi:5262635 /UG=Hs.272586 KIAA0943 protein /FL=gb:NM_013325.1 gb:BC000719.1 gb:AL050288.1 gb:AL080168.1 AL080168 autophagy related 4B, cysteine peptidase ATG4B 23192 NM_013325 /// NM_178326 /// XM_005246992 /// XM_005246993 /// XM_005246995 /// XM_005246996 /// XM_006712371 0000045 // autophagic vacuole assembly // inferred from genetic interaction /// 0000422 // mitochondrion degradation // not recorded /// 0006501 // C-terminal protein lipidation // not recorded /// 0006508 // proteolysis // inferred from direct assay /// 0006612 // protein targeting to membrane // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0051697 // protein delipidation // not recorded 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 204904_at NM_002060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002060.1 /DEF=Homo sapiens gap junction protein, alpha 4, 37kD (connexin 37) (GJA4), mRNA. /FEA=mRNA /GEN=GJA4 /PROD=connexin 37 /DB_XREF=gi:4504002 /UG=Hs.296310 gap junction protein, alpha 4, 37kD (connexin 37) /FL=gb:NM_002060.1 gb:AF180815.1 gb:AF181620.1 gb:M96789.2 NM_002060 gap junction protein, alpha 4, 37kDa GJA4 2701 NM_002060 /// XM_005270750 0001568 // blood vessel development // inferred from electronic annotation /// 0003158 // endothelium development // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005921 // gap junction // traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204905_s_at NM_004280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004280.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 epsilon 1 (EEF1E1), mRNA. /FEA=mRNA /GEN=EEF1E1 /PROD=eukaryotic translation elongation factor 1epsilon 1 /DB_XREF=gi:4758861 /UG=Hs.298581 eukaryotic translation elongation factor 1 epsilon 1 /FL=gb:BC005291.1 gb:AB011079.1 gb:AF054186.1 gb:NM_004280.1 NM_004280 eukaryotic translation elongation factor 1 epsilon 1 EEF1E1 9521 NM_001135650 /// NM_004280 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204906_at BC002363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002363.1 /DEF=Homo sapiens, ribosomal protein S6 kinase, 90kD, polypeptide 2, clone MGC:8629, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S6 kinase, 90kD, polypeptide2 /DB_XREF=gi:12803118 /UG=Hs.301664 ribosomal protein S6 kinase, 90kD, polypeptide 2 /FL=gb:NM_021135.1 gb:BC002363.1 BC002363 ribosomal protein S6 kinase, 90kDa, polypeptide 2 RPS6KA2 6196 NM_001006932 /// NM_021135 /// XM_005267092 /// XM_006715549 0001556 // oocyte maturation // inferred from electronic annotation /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060047 // heart contraction // inferred from electronic annotation /// 0070613 // regulation of protein processing // inferred from electronic annotation /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204907_s_at AI829875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI829875 /FEA=EST /DB_XREF=gi:5450546 /DB_XREF=est:wj58d01.x1 /CLONE=IMAGE:2407009 /UG=Hs.31210 B-cell CLLlymphoma 3 /FL=gb:M31732.1 gb:NM_005178.1 AI829875 B-cell CLL/lymphoma 3 /// microRNA 8085 BCL3 /// MIR8085 602 /// 102465879 NM_005178 /// NR_107052 /// XM_005259129 0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0002268 // follicular dendritic cell differentiation // inferred from electronic annotation /// 0002315 // marginal zone B cell differentiation // inferred from electronic annotation /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010225 // response to UV-C // inferred from direct assay /// 0019730 // antimicrobial humoral response // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // inferred from expression pattern /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045082 // positive regulation of interleukin-10 biosynthetic process // inferred from electronic annotation /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0051101 // regulation of DNA binding // inferred from expression pattern /// 0051457 // maintenance of protein location in nucleus // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032996 // Bcl3-Bcl10 complex // inferred from direct assay /// 0033257 // Bcl3/NF-kappaB2 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030674 // protein binding, bridging // traceable author statement 204908_s_at NM_005178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005178.1 /DEF=Homo sapiens B-cell CLLlymphoma 3 (BCL3), mRNA. /FEA=mRNA /GEN=BCL3 /PROD=B-cell CLLlymphoma 3 /DB_XREF=gi:4885086 /UG=Hs.31210 B-cell CLLlymphoma 3 /FL=gb:M31732.1 gb:NM_005178.1 NM_005178 B-cell CLL/lymphoma 3 /// microRNA 8085 BCL3 /// MIR8085 602 /// 102465879 NM_005178 /// NR_107052 /// XM_005259129 0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0002268 // follicular dendritic cell differentiation // inferred from electronic annotation /// 0002315 // marginal zone B cell differentiation // inferred from electronic annotation /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010225 // response to UV-C // inferred from direct assay /// 0019730 // antimicrobial humoral response // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // inferred from expression pattern /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045082 // positive regulation of interleukin-10 biosynthetic process // inferred from electronic annotation /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0051101 // regulation of DNA binding // inferred from expression pattern /// 0051457 // maintenance of protein location in nucleus // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032996 // Bcl3-Bcl10 complex // inferred from direct assay /// 0033257 // Bcl3/NF-kappaB2 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030674 // protein binding, bridging // traceable author statement 204909_at NM_004397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004397.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 6 (RNA helicase, 54kD) (DDX6), mRNA. /FEA=mRNA /GEN=DDX6 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 6 /DB_XREF=gi:13514828 /UG=Hs.316 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 6 (RNA helicase, 54kD) /FL=gb:NM_004397.2 gb:D17532.1 NM_004397 DEAD (Asp-Glu-Ala-Asp) box helicase 6 DDX6 1656 NM_001257191 /// NM_004397 /// XM_005271417 /// XM_005271418 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204910_s_at AI419307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI419307 /FEA=EST /DB_XREF=gi:4265238 /DB_XREF=est:tf27d02.x1 /CLONE=IMAGE:2097411 /UG=Hs.321576 ring finger protein 22 /FL=gb:AF220020.1 gb:AF045239.1 gb:NM_006458.1 AI419307 tripartite motif containing 3 TRIM3 10612 NM_001248006 /// NM_001248007 /// NM_006458 /// NM_033278 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204911_s_at NM_006458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006458.1 /DEF=Homo sapiens ring finger protein 22 (RNF22), mRNA. /FEA=mRNA /GEN=RNF22 /PROD=ring finger protein 22 /DB_XREF=gi:5453568 /UG=Hs.321576 ring finger protein 22 /FL=gb:AF220020.1 gb:AF045239.1 gb:NM_006458.1 NM_006458 tripartite motif containing 3 TRIM3 10612 NM_001248006 /// NM_001248007 /// NM_006458 /// NM_033278 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204912_at NM_001558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001558.1 /DEF=Homo sapiens interleukin 10 receptor, alpha (IL10RA), mRNA. /FEA=mRNA /GEN=IL10RA /PROD=interleukin 10 receptor, alpha /DB_XREF=gi:4504632 /UG=Hs.327 interleukin 10 receptor, alpha /FL=gb:NM_001558.1 gb:U00672.1 NM_001558 interleukin 10 receptor, alpha IL10RA 3587 NM_001558 /// NR_026691 /// XM_006718833 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0004920 // interleukin-10 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019969 // interleukin-10 binding // inferred from electronic annotation 204913_s_at AI360875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI360875 /FEA=EST /DB_XREF=gi:4112496 /DB_XREF=est:qy01c03.x1 /CLONE=IMAGE:2010724 /UG=Hs.32964 SRY (sex determining region Y)-box 11 /FL=gb:NM_003108.1 gb:AB028641.1 gb:U23752.1 AI360875 SRY (sex determining region Y)-box 11 SOX11 6664 NM_003108 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0014032 // neural crest cell development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from expression pattern /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035332 // positive regulation of hippo signaling // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045778 // positive regulation of ossification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from sequence or structural similarity /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0050672 // negative regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0060022 // hard palate development // inferred from sequence or structural similarity /// 0060023 // soft palate development // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060253 // negative regulation of glial cell proliferation // inferred from mutant phenotype /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060425 // lung morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061053 // somite development // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0061386 // closure of optic fissure // inferred from sequence or structural similarity /// 0072395 // signal transduction involved in cell cycle checkpoint // inferred from expression pattern /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001111 // positive regulation of lens epithelial cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay 204914_s_at AW157202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157202 /FEA=EST /DB_XREF=gi:6228603 /DB_XREF=est:au92g06.x1 /CLONE=IMAGE:2783770 /UG=Hs.32964 SRY (sex determining region Y)-box 11 /FL=gb:NM_003108.1 gb:AB028641.1 gb:U23752.1 AW157202 SRY (sex determining region Y)-box 11 SOX11 6664 NM_003108 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0014032 // neural crest cell development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from expression pattern /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035332 // positive regulation of hippo signaling // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045778 // positive regulation of ossification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from sequence or structural similarity /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0050672 // negative regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0060022 // hard palate development // inferred from sequence or structural similarity /// 0060023 // soft palate development // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060253 // negative regulation of glial cell proliferation // inferred from mutant phenotype /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060425 // lung morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061053 // somite development // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0061386 // closure of optic fissure // inferred from sequence or structural similarity /// 0072395 // signal transduction involved in cell cycle checkpoint // inferred from expression pattern /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001111 // positive regulation of lens epithelial cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay 204915_s_at AB028641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB028641.1 /DEF=Homo sapiens mRNA for SOX11, complete cds. /FEA=mRNA /GEN=sox11 /PROD=SOX11 /DB_XREF=gi:6527111 /UG=Hs.32964 SRY (sex determining region Y)-box 11 /FL=gb:NM_003108.1 gb:AB028641.1 gb:U23752.1 AB028641 SRY (sex determining region Y)-box 11 SOX11 6664 NM_003108 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0014032 // neural crest cell development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from expression pattern /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035332 // positive regulation of hippo signaling // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045778 // positive regulation of ossification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from sequence or structural similarity /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0050672 // negative regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0060022 // hard palate development // inferred from sequence or structural similarity /// 0060023 // soft palate development // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060253 // negative regulation of glial cell proliferation // inferred from mutant phenotype /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060425 // lung morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061053 // somite development // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0061386 // closure of optic fissure // inferred from sequence or structural similarity /// 0072395 // signal transduction involved in cell cycle checkpoint // inferred from expression pattern /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001111 // positive regulation of lens epithelial cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay 204916_at NM_005855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005855.1 /DEF=Homo sapiens receptor (calcitonin) activity modifying protein 1 (RAMP1), mRNA. /FEA=mRNA /GEN=RAMP1 /PROD=receptor (calcitonin) activity modifying protein1 precursor /DB_XREF=gi:5032018 /UG=Hs.32989 receptor (calcitonin) activity modifying protein 1 /FL=gb:BC000548.1 gb:NM_005855.1 NM_005855 receptor (G protein-coupled) activity modifying protein 1 RAMP1 10267 NM_005855 0001525 // angiogenesis // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0015031 // protein transport // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0060050 // positive regulation of protein glycosylation // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0031716 // calcitonin receptor binding // inferred from physical interaction 204917_s_at AV756536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV756536 /FEA=EST /DB_XREF=gi:10914384 /DB_XREF=est:AV756536 /CLONE=BMFAYD08 /UG=Hs.404 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3 /FL=gb:L13744.1 gb:NM_004529.1 AV756536 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 MLLT3 4300 NM_001286691 /// NM_004529 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007379 // segment specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from genetic interaction 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204918_s_at NM_004529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004529.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3 (MLLT3), mRNA. /FEA=mRNA /GEN=MLLT3 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 3 /DB_XREF=gi:4758719 /UG=Hs.404 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3 /FL=gb:L13744.1 gb:NM_004529.1 NM_004529 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 MLLT3 4300 NM_001286691 /// NM_004529 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007379 // segment specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from genetic interaction 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204919_at NM_007244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007244.1 /DEF=Homo sapiens lacrimal proline rich protein (LPRP), mRNA. /FEA=mRNA /GEN=LPRP /PROD=lacrimal proline rich protein /DB_XREF=gi:6005801 /UG=Hs.45033 lacrimal proline rich protein /FL=gb:NM_007244.1 NM_007244 PRH1-PRR4 readthrough /// proline rich 4 (lacrimal) PRH1-PRR4 /// PRR4 11272 /// 100533464 NM_001098538 /// NM_007244 /// NR_037918 0001895 // retina homeostasis // inferred from expression pattern /// 0007601 // visual perception // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 204920_at AF154830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF154830.1 /DEF=Homo sapiens carbamyl phosphate synthetase I mRNA, complete cds. /FEA=mRNA /PROD=carbamyl phosphate synthetase I /DB_XREF=gi:5020419 /UG=Hs.50966 carbamoyl-phosphate synthetase 1, mitochondrial /FL=gb:NM_001875.1 gb:AF154830.1 AF154830 carbamoyl-phosphate synthase 1, mitochondrial CPS1 1373 NM_001122633 /// NM_001122634 /// NM_001875 0000050 // urea cycle // non-traceable author statement /// 0000050 // urea cycle // traceable author statement /// 0001101 // response to acid // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0005980 // glycogen catabolic process // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007494 // midgut development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0019240 // citrulline biosynthetic process // non-traceable author statement /// 0019433 // triglyceride catabolic process // inferred from mutant phenotype /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from mutant phenotype /// 0046209 // nitric oxide metabolic process // inferred from mutant phenotype /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055081 // anion homeostasis // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0070409 // carbamoyl phosphate biosynthetic process // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation /// 0071400 // cellular response to oleic acid // inferred from electronic annotation /// 0071548 // response to dexamethasone // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004087 // carbamoyl-phosphate synthase (ammonia) activity // inferred from mutant phenotype /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 204921_at NM_001481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001481.1 /DEF=Homo sapiens growth arrest-specific 11 (GAS11), mRNA. /FEA=mRNA /GEN=GAS11 /PROD=growth arrest-specific 11 /DB_XREF=gi:4503916 /UG=Hs.54877 growth arrest-specific 11 /FL=gb:AF050079.1 gb:NM_001481.1 NM_001481 growth arrest-specific 8 GAS8 2622 NM_001286205 /// NM_001286208 /// NM_001286209 /// NM_001481 /// NR_023348 /// XM_005256304 /// XM_005256309 /// XM_006721175 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0048870 // cell motility // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0017137 // Rab GTPase binding // inferred from electronic annotation 204922_at NM_024650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024650.1 /DEF=Homo sapiens hypothetical protein FLJ22531 (FLJ22531), mRNA. /FEA=mRNA /GEN=FLJ22531 /PROD=hypothetical protein FLJ22531 /DB_XREF=gi:13375894 /UG=Hs.55613 hypothetical protein FLJ22531 /FL=gb:NM_024650.1 NM_024650 chromosome 11 open reading frame 80 C11orf80 79703 NM_024650 /// NR_048553 204923_at AL023653 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023653 /DEF=Human DNA sequence from clone 753P9 on chromosome Xq25-26.1. Contains the gene coding for Aminopeptidase P (EC 3.4.11.9, XAA-ProX-ProProlineAminoacylproline Aminopeptidase) and a novel gene. Contains ESTs, STSs, GSSs and a gaaa repeat polymorphism /FEA=mRNA_1 /DB_XREF=gi:3550108 /UG=Hs.61469 hypothetical protein /FL=gb:NM_018990.1 AL023653 SAM and SH3 domain containing 3 SASH3 54440 NM_018990 /// XM_006724763 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0002726 // positive regulation of T cell cytokine production // inferred from electronic annotation /// 0002821 // positive regulation of adaptive immune response // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043372 // positive regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051251 // positive regulation of lymphocyte activation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204924_at NM_003264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003264.1 /DEF=Homo sapiens toll-like receptor 2 (TLR2), mRNA. /FEA=mRNA /GEN=TLR2 /PROD=toll-like receptor2 /DB_XREF=gi:4507528 /UG=Hs.63668 toll-like receptor 2 /FL=gb:U88878.1 gb:AF051152.1 gb:NM_003264.1 NM_003264 toll-like receptor 2 TLR2 7097 NM_003264 /// XM_005263193 /// XM_005263194 /// XM_005263195 /// XM_005263196 /// XM_005263197 0001666 // response to hypoxia // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002238 // response to molecule of fungal origin // inferred from electronic annotation /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0002752 // cell surface pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0031663 // lipopolysaccharide-mediated signaling pathway // traceable author statement /// 0032289 // central nervous system myelin formation // inferred from electronic annotation /// 0032493 // response to bacterial lipoprotein // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032700 // negative regulation of interleukin-17 production // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032741 // positive regulation of interleukin-18 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from electronic annotation /// 0034123 // positive regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042495 // detection of triacyl bacterial lipopeptide // inferred from direct assay /// 0042496 // detection of diacyl bacterial lipopeptide // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042892 // chloramphenicol transport // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0052063 // induction by symbiont of defense-related host nitric oxide production // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071221 // cellular response to bacterial lipopeptide // traceable author statement /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071726 // cellular response to diacyl bacterial lipopeptide // inferred from direct assay /// 0071727 // cellular response to triacyl bacterial lipopeptide // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035354 // Toll-like receptor 1-Toll-like receptor 2 protein complex // inferred from direct assay /// 0035355 // Toll-like receptor 2-Toll-like receptor 6 protein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0001875 // lipopolysaccharide receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008329 // signaling pattern recognition receptor activity // inferred from direct assay /// 0042497 // triacyl lipopeptide binding // inferred from direct assay /// 0042498 // diacyl lipopeptide binding // inferred from electronic annotation /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070891 // lipoteichoic acid binding // inferred from electronic annotation /// 0071723 // lipopeptide binding // inferred from electronic annotation 204925_at NM_004937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004937.1 /DEF=Homo sapiens cystinosis, nephropathic (CTNS), mRNA. /FEA=mRNA /GEN=CTNS /PROD=cystinosis, nephropathic /DB_XREF=gi:4826681 /UG=Hs.64837 cystinosis, nephropathic /FL=gb:NM_004937.1 NM_004937 cystinosin, lysosomal cystine transporter CTNS 1497 NM_001031681 /// NM_004937 /// XM_005256485 /// XM_006721463 /// XM_006721464 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015811 // L-cystine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from mutant phenotype /// 0015811 // L-cystine transport // non-traceable author statement /// 0046034 // ATP metabolic process // inferred from mutant phenotype /// 0048058 // compound eye corneal lens development // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // non-traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015184 // L-cystine transmembrane transporter activity // inferred from mutant phenotype /// 0015184 // L-cystine transmembrane transporter activity // non-traceable author statement 204926_at NM_002192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002192.1 /DEF=Homo sapiens inhibin, beta A (activin A, activin AB alpha polypeptide) (INHBA), mRNA. /FEA=mRNA /GEN=INHBA /PROD=inhibin beta A subunit precursor /DB_XREF=gi:4504698 /UG=Hs.727 inhibin, beta A (activin A, activin AB alpha polypeptide) /FL=gb:J03634.1 gb:NM_002192.1 NM_002192 inhibin, beta A INHBA 3624 NM_002192 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from genetic interaction /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from genetic interaction /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from genetic interaction /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // traceable author statement /// 0030218 // erythrocyte differentiation // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0035987 // endodermal cell differentiation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // traceable author statement /// 0042476 // odontogenesis // inferred from genetic interaction /// 0042493 // response to drug // inferred from direct assay /// 0042541 // hemoglobin biosynthetic process // inferred from direct assay /// 0042701 // progesterone secretion // inferred from genetic interaction /// 0045077 // negative regulation of interferon-gamma biosynthetic process // traceable author statement /// 0045578 // negative regulation of B cell differentiation // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045650 // negative regulation of macrophage differentiation // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046880 // regulation of follicle-stimulating hormone secretion // inferred from genetic interaction /// 0046881 // positive regulation of follicle-stimulating hormone secretion // traceable author statement /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0051799 // negative regulation of hair follicle development // inferred from direct assay /// 0060021 // palate development // inferred from genetic interaction /// 0060279 // positive regulation of ovulation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0043509 // activin A complex // inferred from direct assay /// 0043512 // inhibin A complex // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070699 // type II activin receptor binding // inferred from physical interaction 204927_at NM_003475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003475.1 /DEF=Homo sapiens chromosome 11 open reading frame 13 (C11ORF13), mRNA. /FEA=mRNA /GEN=C11ORF13 /PROD=HRAS1-related cluster-1 /DB_XREF=gi:4502482 /UG=Hs.72925 chromosome 11 open reading frame 13 /FL=gb:M91083.1 gb:NM_003475.1 NM_003475 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 RASSF7 8045 NM_001143993 /// NM_001143994 /// NM_003475 /// XM_005253147 /// XM_005253148 /// XM_005253149 /// XM_005253150 /// XM_005253151 /// XM_006718337 /// XM_006718338 /// XM_006725142 /// XM_006725143 /// XM_006725144 /// XM_006725145 /// XM_006725146 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement 204928_s_at NM_019848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019848.2 /DEF=Homo sapiens Protein P3 (P3), mRNA. /FEA=mRNA /GEN=P3 /PROD=Protein P3 /DB_XREF=gi:10938005 /UG=Hs.72980 Protein P3 /FL=gb:NM_019848.2 NM_019848 solute carrier family 10, member 3 SLC10A3 8273 NM_001142391 /// NM_001142392 /// NM_019848 /// XM_005277913 /// XM_006724847 /// XM_006724848 0006810 // transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008508 // bile acid:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 204929_s_at NM_006634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006634.1 /DEF=Homo sapiens vesicle-associated membrane protein 5 (myobrevin) (VAMP5), mRNA. /FEA=mRNA /GEN=VAMP5 /PROD=vesicle-associated membrane protein 5(myobrevin) /DB_XREF=gi:5730111 /UG=Hs.74669 vesicle-associated membrane protein 5 (myobrevin) /FL=gb:AF054825.1 gb:AF077197.1 gb:NM_006634.1 gb:AF151025.1 NM_006634 vesicle-associated membrane protein 5 VAMP5 10791 NM_006634 0006887 // exocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // not recorded /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031201 // SNARE complex // not recorded /// 0031301 // integral component of organelle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded 204930_s_at NM_013979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013979.1 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 1 (BNIP1), transcript variant BNIP1-b, mRNA. /FEA=mRNA /GEN=BNIP1 /PROD=BCL2adenovirus E1B 19kD-interacting protein 1,isoform BNIP1-b /DB_XREF=gi:7524349 /UG=Hs.77572 BCL2adenovirus E1B 19kD-interacting protein 1 /FL=gb:AF083957.1 gb:NM_013979.1 NM_013979 BCL2/adenovirus E1B 19kDa interacting protein 1 BNIP1 662 NM_001205 /// NM_013978 /// NM_013979 /// NM_013980 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from physical interaction /// 0007029 // endoplasmic reticulum organization // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016320 // endoplasmic reticulum membrane fusion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred by curator 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204931_at NM_003206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003206.1 /DEF=Homo sapiens transcription factor 21 (TCF21), mRNA. /FEA=mRNA /GEN=TCF21 /PROD=transcription factor 21 /DB_XREF=gi:4507394 /UG=Hs.78061 transcription factor 21 /FL=gb:AF035718.1 gb:AF047419.1 gb:NM_003206.1 NM_003206 transcription factor 21 TCF21 6943 NM_003206 /// NM_198392 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007530 // sex determination // inferred from sequence or structural similarity /// 0007548 // sex differentiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014707 // branchiomeric skeletal muscle development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048732 // gland development // inferred from sequence or structural similarity /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060425 // lung morphogenesis // inferred from sequence or structural similarity /// 0060426 // lung vasculature development // inferred from sequence or structural similarity /// 0060435 // bronchiole development // inferred from sequence or structural similarity /// 0060539 // diaphragm development // inferred from sequence or structural similarity /// 0060541 // respiratory system development // inferred from sequence or structural similarity /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity /// 0050681 // androgen receptor binding // inferred from sequence or structural similarity /// 0070888 // E-box binding // inferred from sequence or structural similarity 204932_at BF433902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF433902 /FEA=EST /DB_XREF=gi:11446030 /DB_XREF=est:7q56c10.x1 /CLONE=IMAGE:3702163 /UG=Hs.81791 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) /FL=gb:U94332.1 gb:AB002146.1 gb:NM_002546.1 BF433902 tumor necrosis factor receptor superfamily, member 11b TNFRSF11B 4982 NM_002546 0001501 // skeletal system development // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0042489 // negative regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204933_s_at NM_002546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002546.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (TNFRSF11B), mRNA. /FEA=mRNA /GEN=TNFRSF11B /PROD=osteoprotegerin /DB_XREF=gi:4507566 /UG=Hs.81791 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) /FL=gb:U94332.1 gb:AB002146.1 gb:NM_002546.1 NM_002546 tumor necrosis factor receptor superfamily, member 11b TNFRSF11B 4982 NM_002546 0001501 // skeletal system development // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0042489 // negative regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204934_s_at NM_002151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002151.1 /DEF=Homo sapiens hepsin (transmembrane protease, serine 1) (HPN), mRNA. /FEA=mRNA /GEN=HPN /PROD=hepsin (transmembrane protease, serine 1) /DB_XREF=gi:4504480 /UG=Hs.823 hepsin (transmembrane protease, serine 1) /FL=gb:M18930.1 gb:NM_002151.1 NM_002151 hepsin HPN 3249 NM_002151 /// NM_182983 /// XM_005258838 /// XM_006723181 /// XM_006723182 0006508 // proteolysis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010756 // positive regulation of plasminogen activation // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from sequence or structural similarity /// 0060429 // epithelium development // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0097066 // response to thyroid hormone // inferred from sequence or structural similarity /// 0097195 // pilomotor reflex // inferred from sequence or structural similarity /// 2000347 // positive regulation of hepatocyte proliferation // inferred from direct assay /// 2000611 // positive regulation of thyroid hormone generation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0015269 // calcium-activated potassium channel activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 204935_at NM_002828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002828.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 2 (PTPN2), mRNA. /FEA=mRNA /GEN=PTPN2 /PROD=protein tyrosine phosphatase, non-receptor type2 /DB_XREF=gi:4506290 /UG=Hs.82829 protein tyrosine phosphatase, non-receptor type 2 /FL=gb:M25393.1 gb:NM_002828.1 NM_002828 protein tyrosine phosphatase, non-receptor type 2 PTPN2 5771 NM_001207013 /// NM_002828 /// NM_080422 /// NM_080423 /// XM_005258124 /// XM_005258125 /// XM_005258126 /// XM_005258127 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0010888 // negative regulation of lipid storage // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from electronic annotation /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045650 // negative regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050922 // negative regulation of chemotaxis // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1902206 // negative regulation of interleukin-2-mediated signaling pathway // inferred from mutant phenotype /// 1902212 // negative regulation of prolactin signaling pathway // inferred from sequence or structural similarity /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from electronic annotation /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 1902227 // negative regulation of macrophage colony-stimulating factor signaling pathway // inferred from sequence or structural similarity /// 1902233 // negative regulation of positive thymic T cell selection // inferred from sequence or structural similarity /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 204936_at NM_004579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004579.1 /DEF=Homo sapiens mitogen-activating protein kinase kinase kinase kinase 2 (MAP4K2), mRNA. /FEA=mRNA /GEN=MAP4K2 /PROD=mitogen-activating protein kinase kinase kinasekinase 2 /DB_XREF=gi:4759009 /UG=Hs.82979 mitogen-activating protein kinase kinase kinase kinase 2 /FL=gb:NM_004579.1 gb:U07349.1 NM_004579 mitogen-activated protein kinase kinase kinase kinase 2 MAP4K2 5871 NM_004579 /// XM_005274142 /// XM_005274143 /// XM_006718650 /// XM_006718651 0000185 // activation of MAPKKK activity // not recorded /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006903 // vesicle targeting // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction 204937_s_at NM_016325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016325.1 /DEF=Homo sapiens zinc finger protein 274 (ZNF274), mRNA. /FEA=mRNA /GEN=ZNF274 /PROD=KRAB zinc finger protein HFB101L /DB_XREF=gi:7706506 /UG=Hs.83761 zinc finger protein 274 /FL=gb:AB029150.1 gb:NM_016325.1 NM_016325 zinc finger protein 274 ZNF274 10782 NM_001278734 /// NM_001278735 /// NM_016324 /// NM_016325 /// NM_133502 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204938_s_at M60411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60411.1 /DEF=Human phospholamban mRNA, complete cds. /FEA=mRNA /GEN=PLB /PROD=phospholamban /DB_XREF=gi:190018 /UG=Hs.85050 phospholamban /FL=gb:BC005269.1 gb:M63603.1 gb:M60411.1 gb:NM_002667.1 M60411 phospholamban PLN 5350 NM_002667 0002026 // regulation of the force of heart contraction // inferred by curator /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0008015 // blood circulation // non-traceable author statement /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from mutant phenotype /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred by curator /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from sequence or structural similarity /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred by curator /// 0086023 // adrenergic receptor signaling pathway involved in heart process // inferred from electronic annotation /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred by curator /// 0086092 // regulation of the force of heart contraction by cardiac conduction // inferred from electronic annotation /// 0090279 // regulation of calcium ion import // inferred from electronic annotation /// 0090281 // negative regulation of calcium ion import // inferred from sequence or structural similarity /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from direct assay /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901077 // regulation of relaxation of muscle // inferred from electronic annotation /// 1901877 // negative regulation of calcium ion binding // inferred from direct assay /// 1901877 // negative regulation of calcium ion binding // inferred from sequence or structural similarity /// 1901894 // regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901895 // negative regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901897 // regulation of relaxation of cardiac muscle // inferred by curator /// 1902081 // negative regulation of calcium ion import into sarcoplasmic reticulum // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0090534 // calcium ion-transporting ATPase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042030 // ATPase inhibitor activity // inferred from direct assay /// 0042030 // ATPase inhibitor activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 204939_s_at NM_002667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002667.1 /DEF=Homo sapiens phospholamban (PLN), mRNA. /FEA=mRNA /GEN=PLN /PROD=phospholamban /DB_XREF=gi:4505886 /UG=Hs.85050 phospholamban /FL=gb:BC005269.1 gb:M63603.1 gb:M60411.1 gb:NM_002667.1 NM_002667 phospholamban PLN 5350 NM_002667 0002026 // regulation of the force of heart contraction // inferred by curator /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0008015 // blood circulation // non-traceable author statement /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from mutant phenotype /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred by curator /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from sequence or structural similarity /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred by curator /// 0086023 // adrenergic receptor signaling pathway involved in heart process // inferred from electronic annotation /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred by curator /// 0086092 // regulation of the force of heart contraction by cardiac conduction // inferred from electronic annotation /// 0090279 // regulation of calcium ion import // inferred from electronic annotation /// 0090281 // negative regulation of calcium ion import // inferred from sequence or structural similarity /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from direct assay /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901077 // regulation of relaxation of muscle // inferred from electronic annotation /// 1901877 // negative regulation of calcium ion binding // inferred from direct assay /// 1901877 // negative regulation of calcium ion binding // inferred from sequence or structural similarity /// 1901894 // regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901895 // negative regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901897 // regulation of relaxation of cardiac muscle // inferred by curator /// 1902081 // negative regulation of calcium ion import into sarcoplasmic reticulum // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0090534 // calcium ion-transporting ATPase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042030 // ATPase inhibitor activity // inferred from direct assay /// 0042030 // ATPase inhibitor activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 204940_at NM_002667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002667.1 /DEF=Homo sapiens phospholamban (PLN), mRNA. /FEA=mRNA /GEN=PLN /PROD=phospholamban /DB_XREF=gi:4505886 /UG=Hs.85050 phospholamban /FL=gb:BC005269.1 gb:M63603.1 gb:M60411.1 gb:NM_002667.1 NM_002667 phospholamban PLN 5350 NM_002667 0002026 // regulation of the force of heart contraction // inferred by curator /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0008015 // blood circulation // non-traceable author statement /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from mutant phenotype /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred by curator /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from sequence or structural similarity /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred by curator /// 0086023 // adrenergic receptor signaling pathway involved in heart process // inferred from electronic annotation /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred by curator /// 0086092 // regulation of the force of heart contraction by cardiac conduction // inferred from electronic annotation /// 0090279 // regulation of calcium ion import // inferred from electronic annotation /// 0090281 // negative regulation of calcium ion import // inferred from sequence or structural similarity /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from direct assay /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901077 // regulation of relaxation of muscle // inferred from electronic annotation /// 1901877 // negative regulation of calcium ion binding // inferred from direct assay /// 1901877 // negative regulation of calcium ion binding // inferred from sequence or structural similarity /// 1901894 // regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901895 // negative regulation of calcium-transporting ATPase activity // inferred from direct assay /// 1901897 // regulation of relaxation of cardiac muscle // inferred by curator /// 1902081 // negative regulation of calcium ion import into sarcoplasmic reticulum // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0090534 // calcium ion-transporting ATPase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042030 // ATPase inhibitor activity // inferred from direct assay /// 0042030 // ATPase inhibitor activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 204941_s_at AA071510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA071510 /FEA=EST /DB_XREF=gi:1578881 /DB_XREF=est:ze88c07.s1 /CLONE=IMAGE:366060 /UG=Hs.87539 aldehyde dehydrogenase 3 family, member B2 /FL=gb:U37519.1 gb:NM_000695.2 AA071510 aldehyde dehydrogenase 3 family, member B2 ALDH3B2 222 NM_000695 /// NM_001031615 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 204942_s_at NM_000695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000695.2 /DEF=Homo sapiens aldehyde dehydrogenase 3 family, member B2 (ALDH3B2), mRNA. /FEA=mRNA /GEN=ALDH3B2 /PROD=aldehyde dehydrogenase 3B2 /DB_XREF=gi:4580414 /UG=Hs.87539 aldehyde dehydrogenase 3 family, member B2 /FL=gb:U37519.1 gb:NM_000695.2 NM_000695 aldehyde dehydrogenase 3 family, member B2 ALDH3B2 222 NM_000695 /// NM_001031615 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 204943_at NM_021641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021641.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 12 (meltrin alpha) (ADAM12), transcript variant 2, mRNA. /FEA=mRNA /GEN=ADAM12 /PROD=a disintegrin and metalloprotease domain 12,isoform 2 preproprotein /DB_XREF=gi:11496999 /UG=Hs.8850 a disintegrin and metalloproteinase domain 12 (meltrin alpha) /FL=gb:NM_021641.1 gb:AF023477.2 NM_021641 ADAM metallopeptidase domain 12 ADAM12 8038 NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007520 // myoblast fusion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204944_at NM_002841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002841.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, G (PTPRG), mRNA. /FEA=mRNA /GEN=PTPRG /PROD=protein tyrosine phosphatase, receptor type, G /DB_XREF=gi:11386168 /UG=Hs.89627 protein tyrosine phosphatase, receptor type, G /FL=gb:NM_002841.1 gb:L09247.1 NM_002841 protein tyrosine phosphatase, receptor type, G PTPRG 5793 NM_002841 /// XM_005265352 /// XM_005265353 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 204945_at NM_002846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002846.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, N (PTPRN), mRNA. /FEA=mRNA /GEN=PTPRN /PROD=protein tyrosine phosphatase, receptor type, N /DB_XREF=gi:4506320 /UG=Hs.89655 protein tyrosine phosphatase, receptor type, N /FL=gb:NM_002846.1 gb:L18983.1 NM_002846 protein tyrosine phosphatase, receptor type, N PTPRN 5798 NM_001199763 /// NM_001199764 /// NM_002846 0000302 // response to reactive oxygen species // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 204946_s_at NM_004618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004618.1 /DEF=Homo sapiens topoisomerase (DNA) III alpha (TOP3A), mRNA. /FEA=mRNA /GEN=TOP3A /PROD=topoisomerase (DNA) III alpha /DB_XREF=gi:10835217 /UG=Hs.91175 topoisomerase (DNA) III alpha /FL=gb:NM_004618.1 NM_004618 topoisomerase (DNA) III alpha TOP3A 7156 NM_004618 /// XM_005256776 /// XM_005256777 0006265 // DNA topological change // inferred from direct assay /// 0007126 // meiotic nuclear division // traceable author statement 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003917 // DNA topoisomerase type I activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204947_at NM_005225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005225.1 /DEF=Homo sapiens E2F transcription factor 1 (E2F1), mRNA. /FEA=mRNA /GEN=E2F1 /PROD=E2F transcription factor 1 /DB_XREF=gi:12669910 /UG=Hs.96055 E2F transcription factor 1 /FL=gb:NM_005225.1 gb:M96577.1 NM_005225 E2F transcription factor 1 E2F1 1869 NM_005225 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000080 // mitotic G1 phase // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0043276 // anoikis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048255 // mRNA stabilization // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035189 // Rb-E2F complex // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204948_s_at NM_013409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013409.1 /DEF=Homo sapiens follistatin (FST), transcript variant FST344, mRNA. /FEA=mRNA /GEN=FST /PROD=follistatin isoform FST344 precursor /DB_XREF=gi:7242221 /UG=Hs.9914 follistatin /FL=gb:BC004107.1 gb:NM_013409.1 NM_013409 follistatin FST 10468 NM_006350 /// NM_013409 /// XM_005248400 /// XM_005248401 /// XM_005248402 /// XM_005248403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0051798 // positive regulation of hair follicle development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from physical interaction 204949_at NM_002162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002162.2 /DEF=Homo sapiens intercellular adhesion molecule 3 (ICAM3), mRNA. /FEA=mRNA /GEN=ICAM3 /PROD=intercellular adhesion molecule 3 precursor /DB_XREF=gi:12545399 /UG=Hs.99995 intercellular adhesion molecule 3 /FL=gb:NM_002162.2 NM_002162 intercellular adhesion molecule 3 ICAM3 3385 NM_002162 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 204950_at NM_014959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014959.1 /DEF=Homo sapiens KIAA0955 protein (KIAA0955), mRNA. /FEA=mRNA /GEN=KIAA0955 /PROD=KIAA0955 protein /DB_XREF=gi:7662403 /UG=Hs.10031 KIAA0955 protein /FL=gb:AF322184.1 gb:AF331519.1 gb:AY026322.1 gb:AB023172.1 gb:NM_014959.1 NM_014959 caspase recruitment domain family, member 8 CARD8 22900 NM_001184900 /// NM_001184901 /// NM_001184902 /// NM_001184903 /// NM_001184904 /// NM_014959 /// NR_033678 /// NR_033679 /// NR_033680 /// XM_006723091 /// XM_006723092 /// XM_006723093 /// XM_006723094 /// XM_006723095 /// XM_006723096 /// XM_006723097 /// XM_006723098 /// XM_006723099 /// XM_006723100 /// XM_006723101 /// XM_006723102 /// XM_006723103 /// XM_006723104 /// XM_006723105 /// XM_006723106 /// XM_006723107 /// XM_006723108 /// XM_006723109 /// XM_006723110 /// XR_430193 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0032089 // NACHT domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 204951_at NM_004310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004310.1 /DEF=Homo sapiens ras homolog gene family, member H (ARHH), mRNA. /FEA=mRNA /GEN=ARHH /PROD=ras homolog gene family, member H /DB_XREF=gi:4757769 /UG=Hs.109918 ras homolog gene family, member H /FL=gb:NM_004310.1 NM_004310 ras homolog family member H RHOH 399 NM_001278359 /// NM_001278360 /// NM_001278361 /// NM_001278362 /// NM_001278363 /// NM_001278364 /// NM_001278365 /// NM_001278366 /// NM_001278367 /// NM_001278368 /// NM_001278369 /// NM_004310 /// XM_006714013 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030217 // T cell differentiation // non-traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045576 // mast cell activation // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001772 // immunological synapse // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017048 // Rho GTPase binding // non-traceable author statement /// 0019210 // kinase inhibitor activity // inferred from direct assay 204952_at NM_014400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014400.1 /DEF=Homo sapiens GPI-anchored metastasis-associated protein homolog (C4.4A), mRNA. /FEA=mRNA /GEN=C4.4A /PROD=GPI-anchored metastasis-associated proteinhomolog /DB_XREF=gi:7656943 /UG=Hs.11950 GPI-anchored metastasis-associated protein homolog /FL=gb:AF082889.1 gb:NM_014400.1 NM_014400 LY6/PLAUR domain containing 3 LYPD3 27076 NM_014400 0006928 // cellular component movement // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // traceable author statement 0043236 // laminin binding // inferred from electronic annotation 204953_at NM_014841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014841.1 /DEF=Homo sapiens KIAA0656 gene product (KIAA0656), mRNA. /FEA=mRNA /GEN=KIAA0656 /PROD=KIAA0656 gene product /DB_XREF=gi:7662227 /UG=Hs.12477 synaptosomal-associated protein, 91 kDa (mouse) homolog /FL=gb:AB014556.1 gb:NM_014841.1 NM_014841 synaptosomal-associated protein, 91kDa SNAP91 9892 NM_001242792 /// NM_001242793 /// NM_001242794 /// NM_001256717 /// NM_001256718 /// NM_014841 /// NR_026669 /// XM_005248770 /// XM_006715615 /// XM_006715616 /// XM_006715617 /// XM_006715618 /// XM_006715619 /// XM_006715620 /// XM_006715621 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from electronic annotation 204954_s_at NM_004714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004714.1 /DEF=Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B), transcript variant a, mRNA. /FEA=mRNA /GEN=DYRK1B /PROD=dual-specificity tyrosine-(Y)-phosphorylationregulated kinase 1B isoform a /DB_XREF=gi:4758221 /UG=Hs.130988 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B /FL=gb:NM_004714.1 gb:AF205861.1 NM_004714 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B DYRK1B 9149 NM_004714 /// NM_006483 /// NM_006484 /// XM_005259395 /// XM_005259398 /// XM_006723464 /// XM_006723465 0006468 // protein phosphorylation // inferred from direct assay /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204955_at NM_006307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006307.1 /DEF=Homo sapiens sushi-repeat-containing protein, X chromosome (SRPX), mRNA. /FEA=mRNA /GEN=SRPX /PROD=sushi-repeat-containing protein, X chromosome /DB_XREF=gi:5454085 /UG=Hs.15154 sushi-repeat-containing protein, X chromosome /FL=gb:U78093.1 gb:U61374.1 gb:NM_006307.1 NM_006307 sushi-repeat containing protein, X-linked SRPX 8406 NM_001170750 /// NM_001170751 /// NM_001170752 /// NM_006307 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0060244 // negative regulation of cell proliferation involved in contact inhibition // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005776 // autophagic vacuole // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 204956_at NM_002451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002451.2 /DEF=Homo sapiens methylthioadenosine phosphorylase (MTAP), mRNA. /FEA=mRNA /GEN=MTAP /PROD=5-methylthioadenosine phosphorylase /DB_XREF=gi:6006025 /UG=Hs.152817 methylthioadenosine phosphorylase /FL=gb:L40432.1 gb:NM_002451.2 gb:U22233.1 NM_002451 methylthioadenosine phosphorylase MTAP 4507 NM_002451 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0017061 // S-methyl-5-thioadenosine phosphorylase activity // traceable author statement 204957_at NM_002553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002553.1 /DEF=Homo sapiens origin recognition complex, subunit 5 (yeast homolog)-like (ORC5L), mRNA. /FEA=mRNA /GEN=ORC5L /PROD=origin recognition complex, subunit 5 (yeasthomolog)-like /DB_XREF=gi:4505524 /UG=Hs.153138 origin recognition complex, subunit 5 (yeast homolog)-like /FL=gb:U92538.1 gb:AF047599.1 gb:AF049127.1 gb:NM_002553.1 NM_002553 origin recognition complex, subunit 5 ORC5 5001 NM_001197292 /// NM_002553 /// NM_181747 /// XM_006716015 /// XR_242242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay /// 0005664 // nuclear origin of replication recognition complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003688 // DNA replication origin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 204958_at NM_004073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004073.1 /DEF=Homo sapiens cytokine-inducible kinase (CNK), mRNA. /FEA=mRNA /GEN=CNK /PROD=cytokine-inducible kinase /DB_XREF=gi:4758015 /UG=Hs.153640 cytokine-inducible kinase /FL=gb:U56998.1 gb:NM_004073.1 NM_004073 polo-like kinase 3 PLK3 1263 NM_004073 /// XR_246234 0000075 // cell cycle checkpoint // inferred from sequence or structural similarity /// 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000084 // mitotic S phase // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000302 // response to reactive oxygen species // inferred from direct assay /// 0000910 // cytokinesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006970 // response to osmotic stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007113 // endomitotic cell cycle // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0051302 // regulation of cell division // inferred from direct assay /// 0090166 // Golgi disassembly // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 2000777 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 204959_at NM_002432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002432.1 /DEF=Homo sapiens myeloid cell nuclear differentiation antigen (MNDA), mRNA. /FEA=mRNA /GEN=MNDA /PROD=myeloid cell nuclear differentiation antigen /DB_XREF=gi:4505226 /UG=Hs.153837 myeloid cell nuclear differentiation antigen /FL=gb:NM_002432.1 gb:M81750.1 NM_002432 myeloid cell nuclear differentiation antigen MNDA 4332 NM_002432 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204960_at NM_005608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005608.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, C-associated protein (PTPRCAP), mRNA. /FEA=mRNA /GEN=PTPRCAP /PROD=protein tyrosine phosphatase, receptor type,C-associated protein /DB_XREF=gi:5032004 /UG=Hs.155975 protein tyrosine phosphatase, receptor type, C-associated protein /FL=gb:NM_005608.1 NM_005608 protein tyrosine phosphatase, receptor type, C-associated protein PTPRCAP 5790 NM_005608 0006952 // defense response // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0051015 // actin filament binding // inferred from electronic annotation 204961_s_at NM_000265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000265.1 /DEF=Homo sapiens neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) (NCF1), mRNA. /FEA=mRNA /GEN=NCF1 /PROD=neutrophil cytosolic factor 1 /DB_XREF=gi:4557784 /UG=Hs.1583 neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) /FL=gb:BC002816.1 gb:AF330627.1 gb:M55067.1 gb:M25665.1 gb:NM_000265.1 NM_000265 neutrophil cytosolic factor 1 /// neutrophil cytosolic factor 1B pseudogene /// neutrophil cytosolic factor 1C pseudogene NCF1 /// NCF1B /// NCF1C 653361 /// 654816 /// 654817 NM_000265 /// NR_003186 /// NR_003187 /// XM_005250543 /// XM_005250544 /// XR_242262 /// XR_250608 0001878 // response to yeast // inferred from electronic annotation /// 0001909 // leukocyte mediated cytotoxicity // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from direct assay /// 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006968 // cellular defense response // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from mutant phenotype /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // traceable author statement /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0070946 // neutrophil mediated killing of gram-positive bacterium // inferred from electronic annotation /// 0070947 // neutrophil mediated killing of fungus // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0032010 // phagolysosome // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0008942 // nitrite reductase [NAD(P)H] activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from mutant phenotype /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 204962_s_at NM_001809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001809.2 /DEF=Homo sapiens centromere protein A (17kD) (CENPA), mRNA. /FEA=mRNA /GEN=CENPA /PROD=centromere protein A /DB_XREF=gi:4585861 /UG=Hs.1594 centromere protein A (17kD) /FL=gb:NM_001809.2 gb:U14518.1 NM_001809 centromere protein A /// solute carrier family 35, member F6 CENPA /// SLC35F6 1058 /// 54978 NM_001042426 /// NM_001809 /// NM_017877 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0051382 // kinetochore assembly // inferred from direct assay /// 0071459 // protein localization to chromosome, centromeric region // inferred from direct assay /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000778 // condensed nuclear chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000939 // condensed chromosome inner kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204963_at AL136756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136756.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B0115 (from clone DKFZp434B0115); complete cds. /FEA=mRNA /GEN=DKFZp434B0115 /PROD=hypothetical protein /DB_XREF=gi:12053028 /UG=Hs.183428 sarcospan (Kras oncogene-associated gene) /FL=gb:AL136756.1 gb:AF016028.2 gb:NM_005086.2 AL136756 sarcospan SSPN 8082 NM_001135823 /// NM_005086 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 204964_s_at NM_005086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005086.2 /DEF=Homo sapiens sarcospan (Kras oncogene-associated gene) (SSPN), mRNA. /FEA=mRNA /GEN=SSPN /PROD=sarcospan (Kras oncogene-associated gene) /DB_XREF=gi:7669543 /UG=Hs.183428 sarcospan (Kras oncogene-associated gene) /FL=gb:AL136756.1 gb:AF016028.2 gb:NM_005086.2 NM_005086 sarcospan SSPN 8082 NM_001135823 /// NM_005086 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 204965_at NM_000583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000583.1 /DEF=Homo sapiens group-specific component (vitamin D binding protein) (GC), mRNA. /FEA=mRNA /GEN=GC /PROD=group-specific component (vitamin D bindingprotein) /DB_XREF=gi:9845254 /UG=Hs.198246 group-specific component (vitamin D binding protein) /FL=gb:M12654.1 gb:NM_000583.1 NM_000583 group-specific component (vitamin D binding protein) GC 2638 NM_000583 /// NM_001204306 /// NM_001204307 /// XM_006714177 0006810 // transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0042359 // vitamin D metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051180 // vitamin transport // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from physical interaction /// 0005499 // vitamin D binding // traceable author statement /// 0051183 // vitamin transporter activity // inferred from electronic annotation /// 1902118 // calcidiol binding // inferred from direct assay 204966_at NM_001703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001703.1 /DEF=Homo sapiens brain-specific angiogenesis inhibitor 2 (BAI2), mRNA. /FEA=mRNA /GEN=BAI2 /PROD=brain-specific angiogenesis inhibitor 2 /DB_XREF=gi:4502356 /UG=Hs.200586 brain-specific angiogenesis inhibitor 2 /FL=gb:AB005298.1 gb:NM_001703.1 NM_001703 brain-specific angiogenesis inhibitor 2 BAI2 576 NM_001294335 /// NM_001294336 /// NM_001703 /// XM_005271067 /// XM_006710783 /// XM_006710784 /// XM_006710785 /// XM_006710786 /// XM_006710787 /// XM_006710788 /// XM_006710789 /// XM_006710790 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204967_at NM_001649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001649.1 /DEF=Homo sapiens apical protein, Xenopus laevis-like (APXL), mRNA. /FEA=mRNA /GEN=APXL /PROD=apical protein, Xenopus laevis-like /DB_XREF=gi:4502174 /UG=Hs.2391 apical protein, Xenopus laevis-like /FL=gb:NM_001649.1 NM_001649 shroom family member 2 SHROOM2 357 NM_001649 /// XM_005274500 0000902 // cell morphogenesis // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008057 // eye pigment granule organization // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030835 // negative regulation of actin filament depolymerization // inferred from electronic annotation /// 0032401 // establishment of melanosome localization // inferred from sequence or structural similarity /// 0032438 // melanosome organization // inferred from sequence or structural similarity /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043482 // cellular pigment accumulation // inferred from sequence or structural similarity /// 0043583 // ear development // inferred from sequence or structural similarity /// 0045176 // apical protein localization // inferred from sequence or structural similarity /// 0045217 // cell-cell junction maintenance // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from sequence or structural similarity /// 0015280 // ligand-gated sodium channel activity // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity 204968_at NM_021184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021184.1 /DEF=Homo sapiens G4 protein (G4), mRNA. /FEA=mRNA /GEN=G4 /PROD=G4 protein /DB_XREF=gi:10863984 /UG=Hs.247323 G4 protein /FL=gb:NM_021184.1 NM_021184 chromosome 6 open reading frame 47 C6orf47 57827 NM_021184 0005737 // cytoplasm // inferred from direct assay 204969_s_at NM_002906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002906.1 /DEF=Homo sapiens radixin (RDX), mRNA. /FEA=mRNA /GEN=RDX /PROD=radixin /DB_XREF=gi:4506466 /UG=Hs.250613 radixin /FL=gb:L02320.1 gb:NM_002906.1 NM_002906 radixin RDX 5962 NM_001260492 /// NM_001260493 /// NM_001260494 /// NM_001260495 /// NM_001260496 /// NM_002906 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204970_s_at NM_002359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002359.1 /DEF=Homo sapiens v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G (MAFG), mRNA. /FEA=mRNA /GEN=MAFG /PROD=v-maf musculoaponeurotic fibrosarcoma (avian)oncogene family, protein G /DB_XREF=gi:4505072 /UG=Hs.252229 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G /FL=gb:AF059195.1 gb:NM_002359.1 NM_002359 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G MAFG 4097 NM_002359 /// NM_032711 /// XM_006722282 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0030641 // regulation of cellular pH // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045604 // regulation of epidermal cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204971_at NM_005213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005213.1 /DEF=Homo sapiens cystatin A (stefin A) (CSTA), mRNA. /FEA=mRNA /GEN=CSTA /PROD=cystatin A (stefin A) /DB_XREF=gi:4885164 /UG=Hs.2621 cystatin A (stefin A) /FL=gb:NM_005213.1 NM_005213 cystatin A (stefin A) CSTA 1475 NM_005213 0007155 // cell adhesion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0001533 // cornified envelope // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005198 // structural molecule activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay 204972_at NM_016817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016817.1 /DEF=Homo sapiens 2-5oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA. /FEA=mRNA /GEN=OAS2 /PROD=2-5oligoadenylate synthetase 2, isoform p71 /DB_XREF=gi:8051624 /UG=Hs.264981 2-5oligoadenylate synthetase 2 /FL=gb:M87434.1 gb:NM_016817.1 NM_016817 2'-5'-oligoadenylate synthetase 2, 69/71kDa OAS2 4939 NM_001032731 /// NM_002535 /// NM_016817 0002376 // immune system process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from direct assay /// 0006401 // RNA catabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0018377 // protein myristoylation // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204973_at NM_000166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000166.1 /DEF=Homo sapiens gap junction protein, beta 1, 32kD (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) (GJB1), mRNA. /FEA=mRNA /GEN=GJB1 /PROD=gap junction protein, beta 1, 32kD (connexin 32,Charcot-Marie-Tooth neuropathy, X-linked) /DB_XREF=gi:4504004 /UG=Hs.2679 gap junction protein, beta 1, 32kD (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) /FL=gb:BC002805.1 gb:NM_000166.1 NM_000166 gap junction protein, beta 1, 32kDa GJB1 2705 NM_000166 /// NM_001097642 0006810 // transport // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015868 // purine ribonucleotide transport // inferred from electronic annotation /// 0016264 // gap junction assembly // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204974_at AA988241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA988241 /FEA=EST /DB_XREF=gi:3173933 /DB_XREF=est:os08g10.s1 /CLONE=IMAGE:1604802 /UG=Hs.27744 RAB3A, member RAS oncogene family /FL=gb:NM_002866.1 gb:M28210.1 gb:AF254795.1 AA988241 RAB3A, member RAS oncogene family RAB3A 5864 NM_002866 0003016 // respiratory system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from mutant phenotype /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016188 // synaptic vesicle maturation // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031630 // regulation of synaptic vesicle fusion to presynaptic membrane // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0048790 // maintenance of presynaptic active zone structure // inferred from electronic annotation /// 0050975 // sensory perception of touch // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0001671 // ATPase activator activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 204975_at NM_001424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001424.1 /DEF=Homo sapiens epithelial membrane protein 2 (EMP2), mRNA. /FEA=mRNA /GEN=EMP2 /PROD=epithelial membrane protein 2 /DB_XREF=gi:4503560 /UG=Hs.29191 epithelial membrane protein 2 /FL=gb:U52100.1 gb:NM_001424.1 NM_001424 epithelial membrane protein 2 EMP2 2013 NM_001424 /// XM_006720864 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005178 // integrin binding // inferred from physical interaction 204976_s_at AK023637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023637.1 /DEF=Homo sapiens cDNA FLJ13575 fis, clone PLACE1008630. /FEA=mRNA /DB_XREF=gi:10435621 /UG=Hs.326142 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1 /FL=gb:NM_015365.1 AK023637 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 AMMECR1 9949 NM_001025580 /// NM_001171689 /// NM_015365 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204977_at NM_004398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004398.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 10 (RNA helicase) (DDX10), mRNA. /FEA=mRNA /GEN=DDX10 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 10 /DB_XREF=gi:13514830 /UG=Hs.41706 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 10 (RNA helicase) /FL=gb:AB040537.1 gb:U28042.1 gb:NM_004398.2 NM_004398 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 DDX10 1662 NM_004398 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204978_at NM_007056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007056.1 /DEF=Homo sapiens suppressor of white apricot homolog 2 (SWAP2), mRNA. /FEA=mRNA /GEN=SWAP2 /PROD=suppressor of white apricot homolog 2 /DB_XREF=gi:5902129 /UG=Hs.43543 suppressor of white apricot homolog 2 /FL=gb:AF042800.1 gb:NM_007056.1 NM_007056 CLK4-associating serine/arginine rich protein CLASRP 11129 NM_001278439 /// NM_007056 /// NR_103529 /// XM_006722991 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 204979_s_at NM_007341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007341.1 /DEF=Homo sapiens SH3 domain binding glutamic acid-rich protein (SH3BGR), mRNA. /FEA=mRNA /GEN=SH3BGR /PROD=SH3 domain binding glutamic acid-rich protein /DB_XREF=gi:6677928 /UG=Hs.47438 SH3 domain binding glutamic acid-rich protein /FL=gb:NM_007341.1 NM_007341 SH3 domain binding glutamate-rich protein SH3BGR 6450 NM_001001713 /// NM_007341 /// XM_005261023 /// XM_005261024 /// XM_005261025 /// XM_006724041 /// XM_006724042 0006461 // protein complex assembly // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005829 // cytosol // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 204980_at NM_004898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004898.1 /DEF=Homo sapiens clock (mouse) homolog (CLOCK), mRNA. /FEA=mRNA /GEN=CLOCK /PROD=clock (mouse) homolog /DB_XREF=gi:4758009 /UG=Hs.50722 clock (mouse) homolog /FL=gb:AB002332.1 gb:AF011568.1 gb:NM_004898.1 NM_004898 clock circadian regulator CLOCK 9575 NM_001267843 /// NM_004898 /// XM_005265787 /// XM_006714054 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // traceable author statement /// 0009648 // photoperiodism // traceable author statement /// 0016573 // histone acetylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 2000074 // regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0004402 // histone acetyltransferase activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 204981_at NM_002555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002555.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 1-like (SLC22A1L), mRNA. /FEA=mRNA /GEN=SLC22A1L /PROD=organic cation transporter-like 2 /DB_XREF=gi:4505526 /UG=Hs.50868 solute carrier family 22 (organic cation transporter), member 1-like /FL=gb:AF028738.1 gb:AF037064.1 gb:AF059663.1 gb:AF030302.1 gb:AF070479.1 gb:AB012083.1 gb:NM_002555.1 NM_002555 solute carrier family 22, member 18 SLC22A18 5002 NM_002555 /// NM_183233 /// XM_005252952 /// XM_005252953 /// XM_006718243 /// XM_006725127 /// XM_006725128 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred from direct assay /// 0007588 // excretion // non-traceable author statement /// 0015695 // organic cation transport // non-traceable author statement /// 0015893 // drug transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0015238 // drug transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 204982_at NM_014776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014776.1 /DEF=Homo sapiens G protein-coupled receptor kinase-interactor 2 (GIT2), mRNA. /FEA=mRNA /GEN=GIT2 /PROD=G protein-coupled receptor kinase-interactor 2 /DB_XREF=gi:7661943 /UG=Hs.57734 G protein-coupled receptor kinase-interactor 2 /FL=gb:BC001379.1 gb:D63482.1 gb:NM_014776.1 NM_014776 G protein-coupled receptor kinase interacting ArfGAP 2 GIT2 9815 NM_001135213 /// NM_001135214 /// NM_014776 /// NM_057169 /// NM_057170 /// NM_139201 /// XM_005253997 /// XM_005254000 /// XM_006719707 /// XM_006719708 /// XM_006719709 /// XM_006719710 /// XM_006719711 /// XM_006719712 /// XM_006719713 /// XM_006719714 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045095 // keratin filament // inferred from direct assay /// 0045179 // apical cortex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204983_s_at AF064826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064826.1 /DEF=Homo sapiens glypican 4 (GPC4) mRNA, complete cds. /FEA=mRNA /GEN=GPC4 /PROD=glypican 4 /DB_XREF=gi:3420276 /UG=Hs.58367 glypican 4 /FL=gb:AF064826.1 gb:AF030186.1 gb:NM_001448.1 AF064826 glypican 4 GPC4 2239 NM_001448 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 204984_at NM_001448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001448.1 /DEF=Homo sapiens glypican 4 (GPC4), mRNA. /FEA=mRNA /GEN=GPC4 /PROD=glypican 4 /DB_XREF=gi:4504082 /UG=Hs.58367 glypican 4 /FL=gb:AF064826.1 gb:AF030186.1 gb:NM_001448.1 NM_001448 glypican 4 GPC4 2239 NM_001448 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 204985_s_at NM_024108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024108.1 /DEF=Homo sapiens hypothetical protein MGC2650 (MGC2650), mRNA. /FEA=mRNA /GEN=MGC2650 /PROD=hypothetical protein MGC2650 /DB_XREF=gi:13129119 /UG=Hs.61273 hypothetical protein MGC2650 /FL=gb:BC001907.1 gb:NM_024108.1 gb:BC004450.1 NM_024108 trafficking protein particle complex 6A TRAPPC6A 79090 NM_001270891 /// NM_001270892 /// NM_001270893 /// NM_024108 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204986_s_at NM_016151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016151.1 /DEF=Homo sapiens prostate derived STE20-like kinase PSK (PSK), mRNA. /FEA=mRNA /GEN=PSK /PROD=prostate derived STE20-like kinase PSK /DB_XREF=gi:7706400 /UG=Hs.66141 prostate derived STE20-like kinase PSK /FL=gb:AF061943.1 gb:NM_016151.1 NM_016151 TAO kinase 2 TAOK2 9344 NM_001252043 /// NM_004783 /// NM_016151 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction 204987_at NM_002216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002216.1 /DEF=Homo sapiens inter-alpha (globulin) inhibitor, H2 polypeptide (ITIH2), mRNA. /FEA=mRNA /GEN=ITIH2 /PROD=inter-alpha (globulin) inhibitor, H2polypeptide /DB_XREF=gi:4504782 /UG=Hs.75285 inter-alpha (globulin) inhibitor, H2 polypeptide /FL=gb:NM_002216.1 NM_002216 inter-alpha-trypsin inhibitor heavy chain 2 ITIH2 3698 NM_002216 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 204988_at NM_005141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005141.1 /DEF=Homo sapiens fibrinogen, B beta polypeptide (FGB), mRNA. /FEA=mRNA /GEN=FGB /PROD=fibrinogen, beta chain preproprotein /DB_XREF=gi:11761630 /UG=Hs.7645 fibrinogen, B beta polypeptide /FL=gb:NM_005141.1 NM_005141 fibrinogen beta chain FGB 2244 NM_001184741 /// NM_005141 0002576 // platelet degranulation // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0044320 // cellular response to leptin stimulus // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from direct assay /// 0045921 // positive regulation of exocytosis // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051258 // protein polymerization // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 204989_s_at BF305661 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF305661 /FEA=EST /DB_XREF=gi:11252643 /DB_XREF=est:601893502F1 /CLONE=IMAGE:4139065 /UG=Hs.85266 integrin, beta 4 /FL=gb:NM_000213.1 BF305661 integrin, beta 4 ITGB4 3691 NM_000213 /// NM_001005619 /// NM_001005731 /// XM_005257309 /// XM_005257311 /// XM_005257312 /// XM_006721866 /// XM_006721867 /// XM_006721868 /// XM_006721869 /// XM_006721870 0006914 // autophagy // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204990_s_at NM_000213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000213.1 /DEF=Homo sapiens integrin, beta 4 (ITGB4), mRNA. /FEA=mRNA /GEN=ITGB4 /PROD=integrin, beta 4 /DB_XREF=gi:4504768 /UG=Hs.85266 integrin, beta 4 /FL=gb:NM_000213.1 NM_000213 integrin, beta 4 ITGB4 3691 NM_000213 /// NM_001005619 /// NM_001005731 /// XM_005257309 /// XM_005257311 /// XM_005257312 /// XM_006721866 /// XM_006721867 /// XM_006721868 /// XM_006721869 /// XM_006721870 0006914 // autophagy // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204991_s_at NM_000268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000268.1 /DEF=Homo sapiens neurofibromin 2 (bilateral acoustic neuroma) (NF2), mRNA. /FEA=mRNA /GEN=NF2 /PROD=merlin /DB_XREF=gi:4557794 /UG=Hs.902 neurofibromin 2 (bilateral acoustic neuroma) /FL=gb:L11353.1 gb:NM_000268.1 NM_000268 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 204992_s_at NM_002628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002628.1 /DEF=Homo sapiens profilin 2 (PFN2), mRNA. /FEA=mRNA /GEN=PFN2 /PROD=profilin 2 /DB_XREF=gi:4505750 /UG=Hs.91747 profilin 2 /FL=gb:L10678.1 gb:NM_002628.1 NM_002628 profilin 2 PFN2 5217 NM_002628 /// NM_053024 0008064 // regulation of actin polymerization or depolymerization // non-traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from genetic interaction /// 0032233 // positive regulation of actin filament bundle assembly // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 1900028 // negative regulation of ruffle assembly // inferred from mutant phenotype /// 2000300 // regulation of synaptic vesicle exocytosis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0043195 // terminal bouton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000774 // adenyl-nucleotide exchange factor activity // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0003785 // actin monomer binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay 204993_at NM_002073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002073.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide (GNAZ), mRNA. /FEA=mRNA /GEN=GNAZ /PROD=guanine nucleotide binding protein, alpha zpolypeptide /DB_XREF=gi:4504050 /UG=Hs.92002 guanine nucleotide binding protein (G protein), alpha z polypeptide /FL=gb:J03260.1 gb:NM_002073.1 NM_002073 guanine nucleotide binding protein (G protein), alpha z polypeptide GNAZ 2781 NM_002073 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement 0005635 // nuclear envelope // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 204994_at NM_002463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002463.1 /DEF=Homo sapiens myxovirus (influenza) resistance 2, homolog of murine (MX2), mRNA. /FEA=mRNA /GEN=MX2 /PROD=myxovirus (influenza) resistance 2, homolog ofmurine /DB_XREF=gi:11342663 /UG=Hs.926 myxovirus (influenza) resistance 2, homolog of murine /FL=gb:NM_002463.1 gb:M30818.1 gb:M33883.1 NM_002463 myxovirus (influenza virus) resistance 2 (mouse) MX2 4600 NM_002463 /// XM_005260983 /// XM_005260984 /// XM_006724006 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046822 // regulation of nucleocytoplasmic transport // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from mutant phenotype 204995_at AL567411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567411 /FEA=EST /DB_XREF=gi:12920744 /DB_XREF=est:AL567411 /CLONE=CS0DF024YM22 (3 prime) /UG=Hs.93597 cyclin-dependent kinase 5, regulatory subunit 1 (p35) /FL=gb:NM_003885.1 AL567411 cyclin-dependent kinase 5, regulatory subunit 1 (p35) CDK5R1 8851 NM_003885 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007420 // brain development // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021722 // superior olivary nucleus maturation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0033136 // serine phosphorylation of STAT3 protein // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // non-traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016533 // cyclin-dependent protein kinase 5 holoenzyme complex // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043292 // contractile fiber // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004672 // protein kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from sequence or structural similarity /// 0016534 // cyclin-dependent protein kinase 5 activator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation 204996_s_at NM_003885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003885.1 /DEF=Homo sapiens cyclin-dependent kinase 5, regulatory subunit 1 (p35) (CDK5R1), mRNA. /FEA=mRNA /GEN=CDK5R1 /PROD=cyclin-dependent kinase 5, regulatory subunit 1(p35) /DB_XREF=gi:4502736 /UG=Hs.93597 cyclin-dependent kinase 5, regulatory subunit 1 (p35) /FL=gb:NM_003885.1 NM_003885 cyclin-dependent kinase 5, regulatory subunit 1 (p35) CDK5R1 8851 NM_003885 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007420 // brain development // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021722 // superior olivary nucleus maturation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0033136 // serine phosphorylation of STAT3 protein // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // non-traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016533 // cyclin-dependent protein kinase 5 holoenzyme complex // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043292 // contractile fiber // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004672 // protein kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from sequence or structural similarity /// 0016534 // cyclin-dependent protein kinase 5 activator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation 204997_at NM_005276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005276.1 /DEF=Homo sapiens glycerol-3-phosphate dehydrogenase 1 (soluble) (GPD1), mRNA. /FEA=mRNA /GEN=GPD1 /PROD=glycerol-3-phosphate dehydrogenase 1 (soluble) /DB_XREF=gi:4885290 /UG=Hs.9739 glycerol-3-phosphate dehydrogenase 1 (soluble) /FL=gb:NM_005276.1 gb:L34041.1 NM_005276 glycerol-3-phosphate dehydrogenase 1 (soluble) GPD1 2819 NM_001257199 /// NM_005276 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006116 // NADH oxidation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046168 // glycerol-3-phosphate catabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009331 // glycerol-3-phosphate dehydrogenase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004367 // glycerol-3-phosphate dehydrogenase [NAD+] activity // inferred from electronic annotation /// 0004368 // glycerol-3-phosphate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 204998_s_at NM_012068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012068.2 /DEF=Homo sapiens activating transcription factor 5 (ATF5), mRNA. /FEA=mRNA /GEN=ATF5 /PROD=activating transcription factor 5 /DB_XREF=gi:12597624 /UG=Hs.9754 activating transcription factor 5 /FL=gb:AF305687.1 gb:AB021663.2 gb:NM_012068.2 gb:BC005174.1 NM_012068 activating transcription factor 5 ATF5 22809 NM_001193646 /// NM_001290746 /// NM_012068 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021891 // olfactory bulb interneuron development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204999_s_at BC005174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005174.1 /DEF=Homo sapiens, activating transcription factor 5, clone MGC:842, mRNA, complete cds. /FEA=mRNA /PROD=activating transcription factor 5 /DB_XREF=gi:13477389 /UG=Hs.9754 activating transcription factor 5 /FL=gb:AF305687.1 gb:AB021663.2 gb:NM_012068.2 gb:BC005174.1 BC005174 activating transcription factor 5 ATF5 22809 NM_001193646 /// NM_001290746 /// NM_012068 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021891 // olfactory bulb interneuron development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205000_at NM_004660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004660.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide, Y chromosome (DBY), mRNA. /FEA=mRNA /GEN=DBY /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide, Ychromosome /DB_XREF=gi:13514808 /UG=Hs.99120 DEADH (Asp-Glu-Ala-AspHis) box polypeptide, Y chromosome /FL=gb:NM_004660.2 gb:AF000984.1 gb:AF000985.1 NM_004660 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked DDX3Y 8653 NM_001122665 /// NM_004660 /// XM_005262564 /// XM_006724877 /// XM_006724878 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205001_s_at AF000985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000985.1 /DEF=Homo sapiens dead box, Y isoform (DBY) mRNA, alternative transcript 1, complete cds. /FEA=mRNA /GEN=DBY /PROD=dead box, Y isoform /DB_XREF=gi:2580555 /UG=Hs.99120 DEADH (Asp-Glu-Ala-AspHis) box polypeptide, Y chromosome /FL=gb:NM_004660.2 gb:AF000984.1 gb:AF000985.1 AF000985 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked DDX3Y 8653 NM_001122665 /// NM_004660 /// XM_005262564 /// XM_006724877 /// XM_006724878 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205002_at NM_015699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015699.1 /DEF=Homo sapiens hypothetical protein (DJ159A19.3), mRNA. /FEA=mRNA /GEN=DJ159A19.3 /PROD=hypothetical protein /DB_XREF=gi:7661559 /UG=Hs.10700 hypothetical protein /FL=gb:BC002677.1 gb:U79259.1 gb:NM_015699.1 NM_015699 AT hook, DNA binding motif, containing 1 AHDC1 27245 NM_001029882 /// XM_005245848 /// XM_005245849 /// XM_005245850 /// XM_005245851 /// XM_005245852 /// XM_005245853 0003677 // DNA binding // inferred from electronic annotation 205003_at NM_014705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014705.1 /DEF=Homo sapiens KIAA0716 gene product (KIAA0716), mRNA. /FEA=mRNA /GEN=KIAA0716 /PROD=KIAA0716 gene product /DB_XREF=gi:7662263 /UG=Hs.118140 KIAA0716 gene product /FL=gb:AB018259.1 gb:NM_014705.1 NM_014705 dedicator of cytokinesis 4 DOCK4 9732 NM_014705 /// XM_006716188 /// XM_006716189 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032421 // stereocilium bundle // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0048365 // Rac GTPase binding // inferred from direct assay 205004_at NM_017544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017544.1 /DEF=Homo sapiens transcription factor NRF (NRF), mRNA. /FEA=mRNA /GEN=NRF /PROD=transcription factor NRF /DB_XREF=gi:8923943 /UG=Hs.119018 transcription factor NRF /FL=gb:NM_017544.1 NM_017544 NFKB repressing factor NKRF 55922 NM_001173487 /// NM_001173488 /// NM_017544 /// XM_005262443 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 205005_s_at AW293531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW293531 /FEA=EST /DB_XREF=gi:6700167 /DB_XREF=est:UI-H-BI2-ahq-d-03-0-UI.s1 /CLONE=IMAGE:2727604 /UG=Hs.122647 N-myristoyltransferase 2 /FL=gb:AF043325.1 gb:NM_004808.1 AW293531 N-myristoyltransferase 2 NMT2 9397 NM_004808 /// XM_005252642 /// XM_005252643 /// XM_006717539 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 205006_s_at NM_004808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004808.1 /DEF=Homo sapiens N-myristoyltransferase 2 (NMT2), mRNA. /FEA=mRNA /GEN=NMT2 /PROD=glycylpeptide N-tetradecanoyltransferase 2 /DB_XREF=gi:4758815 /UG=Hs.122647 N-myristoyltransferase 2 /FL=gb:AF043325.1 gb:NM_004808.1 NM_004808 N-myristoyltransferase 2 NMT2 9397 NM_004808 /// XM_005252642 /// XM_005252643 /// XM_006717539 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 205007_s_at AI478592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478592 /FEA=EST /DB_XREF=gi:4371818 /DB_XREF=est:tm54a01.x1 /CLONE=IMAGE:2161896 /UG=Hs.129867 DNA-dependent protein kinase catalytic subunit-interacting protein 2 /FL=gb:AB012955.1 gb:NM_006383.1 AI478592 calcium and integrin binding family member 2 CIB2 10518 NM_001271888 /// NM_001271889 /// NM_006383 /// XM_005254126 /// XM_005254128 /// XM_006720373 /// XM_006720374 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205008_s_at NM_006383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006383.1 /DEF=Homo sapiens DNA-dependent protein kinase catalytic subunit-interacting protein 2 (KIP2), mRNA. /FEA=mRNA /GEN=KIP2 /PROD=DNA-dependent protein kinase catalyticsubunit-interacting protein 2 /DB_XREF=gi:5453707 /UG=Hs.129867 DNA-dependent protein kinase catalytic subunit-interacting protein 2 /FL=gb:AB012955.1 gb:NM_006383.1 NM_006383 calcium and integrin binding family member 2 CIB2 10518 NM_001271888 /// NM_001271889 /// NM_006383 /// XM_005254126 /// XM_005254128 /// XM_006720373 /// XM_006720374 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205009_at NM_003225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003225.1 /DEF=Homo sapiens trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in) (TFF1), mRNA. /FEA=mRNA /GEN=TFF1 /PROD=trefoil factor 1 (breast cancer,estrogen-inducible sequence expressed in) /DB_XREF=gi:4507450 /UG=Hs.1406 trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in) /FL=gb:NM_003225.1 NM_003225 trefoil factor 1 TFF1 7031 NM_003225 0005975 // carbohydrate metabolic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 205010_at NM_019067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019067.1 /DEF=Homo sapiens hypothetical protein (FLJ10613), mRNA. /FEA=mRNA /GEN=FLJ10613 /PROD=hypothetical protein /DB_XREF=gi:9506610 /UG=Hs.142217 hypothetical protein /FL=gb:NM_019067.1 NM_019067 guanine nucleotide binding protein-like 3 (nucleolar)-like GNL3L 54552 NM_001184819 /// NM_019067 0006184 // GTP catabolic process // not recorded /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205011_at NM_014622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014622.1 /DEF=Homo sapiens loss of heterozygosity, 11, chromosomal region 2, gene A (LOH11CR2A), mRNA. /FEA=mRNA /GEN=LOH11CR2A /PROD=loss of heterozygosity, 11, chromosomal region2, gene A /DB_XREF=gi:7657310 /UG=Hs.152944 loss of heterozygosity, 11, chromosomal region 2, gene A /FL=gb:AF002672.1 gb:NM_014622.1 NM_014622 von Willebrand factor A domain containing 5A VWA5A 4013 NM_001130142 /// NM_014622 /// NM_198315 0005634 // nucleus // inferred from direct assay 205012_s_at NM_005326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005326.1 /DEF=Homo sapiens hydroxyacyl glutathione hydrolase (HAGH), mRNA. /FEA=mRNA /GEN=HAGH /PROD=hydroxyacyl glutathione hydrolase /DB_XREF=gi:4885388 /UG=Hs.155482 hydroxyacyl glutathione hydrolase /FL=gb:BC000840.1 gb:BC002627.1 gb:NM_005326.1 NM_005326 hydroxyacylglutathione hydrolase HAGH 3029 NM_001040427 /// NM_001286249 /// NM_005326 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004416 // hydroxyacylglutathione hydrolase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205013_s_at NM_000675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000675.2 /DEF=Homo sapiens adenosine A2a receptor (ADORA2A), mRNA. /FEA=mRNA /GEN=ADORA2A /PROD=adenosine A2a receptor /DB_XREF=gi:5921991 /UG=Hs.1613 adenosine A2a receptor /FL=gb:M97370.1 gb:NM_000675.2 NM_000675 adenosine A2a receptor /// SPECC1L-ADORA2A readthrough (NMD candidate) ADORA2A /// SPECC1L-ADORA2A 135 /// 101730217 NM_000675 /// NM_001278497 /// NM_001278498 /// NM_001278499 /// NM_001278500 /// NR_103543 /// NR_103544 /// NR_103546 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006909 // phagocytosis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007600 // sensory perception // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014057 // positive regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0030835 // negative regulation of actin filament depolymerization // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040013 // negative regulation of locomotion // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045938 // positive regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0046636 // negative regulation of alpha-beta T cell activation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032279 // asymmetric synapse // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0001609 // G-protein coupled adenosine receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031802 // type 5 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from electronic annotation 205014_at NM_005130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005130.1 /DEF=Homo sapiens heparin-binding growth factor binding protein (HBP17), mRNA. /FEA=mRNA /GEN=HBP17 /PROD=heparin-binding growth factor binding protein /DB_XREF=gi:4826753 /UG=Hs.1690 heparin-binding growth factor binding protein /FL=gb:BC003628.1 gb:M60047.1 gb:NM_005130.1 NM_005130 fibroblast growth factor binding protein 1 FGFBP1 9982 NM_005130 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // traceable author statement /// 0017134 // fibroblast growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 205015_s_at M31172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31172.1 /DEF=Human transforming growth factor-alpha mRNA, complete cds. /FEA=mRNA /GEN=TGFA /DB_XREF=gi:339537 /UG=Hs.170009 transforming growth factor, alpha /FL=gb:BC005308.1 gb:M31172.1 gb:K03222.1 gb:NM_003236.1 M31172 transforming growth factor, alpha TGFA 7039 NM_001099691 /// NM_003236 /// XM_005264522 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0048523 // negative regulation of cellular process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 205016_at NM_003236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003236.1 /DEF=Homo sapiens transforming growth factor, alpha (TGFA), mRNA. /FEA=mRNA /GEN=TGFA /PROD=transforming growth factor, alpha /DB_XREF=gi:4507460 /UG=Hs.170009 transforming growth factor, alpha /FL=gb:BC005308.1 gb:M31172.1 gb:K03222.1 gb:NM_003236.1 NM_003236 transforming growth factor, alpha TGFA 7039 NM_001099691 /// NM_003236 /// XM_005264522 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0048523 // negative regulation of cellular process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 205017_s_at AI088145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI088145 /FEA=EST /DB_XREF=gi:3427121 /DB_XREF=est:oz95h07.x1 /CLONE=IMAGE:1683133 /UG=Hs.184340 C3H-type zinc finger protein; similar to D. melanogaster muscleblind B protein /FL=gb:AF061261.1 gb:NM_005757.2 AI088145 muscleblind-like splicing regulator 2 MBNL2 10150 NM_144778 /// NM_207304 /// XM_005254018 /// XM_005254019 /// XM_005254020 /// XM_005254021 /// XM_005254022 /// XM_006719912 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205018_s_at NM_005757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005757.2 /DEF=Homo sapiens C3H-type zinc finger protein; similar to D. melanogaster muscleblind B protein (MBLL), mRNA. /FEA=mRNA /GEN=MBLL /PROD=C3H-type zinc finger protein /DB_XREF=gi:9665257 /UG=Hs.184340 C3H-type zinc finger protein; similar to D. melanogaster muscleblind B protein /FL=gb:AF061261.1 gb:NM_005757.2 NM_005757 muscleblind-like splicing regulator 2 MBNL2 10150 NM_144778 /// NM_207304 /// XM_005254018 /// XM_005254019 /// XM_005254020 /// XM_005254021 /// XM_005254022 /// XM_006719912 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205019_s_at NM_004624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004624.1 /DEF=Homo sapiens vasoactive intestinal peptide receptor 1 (VIPR1), mRNA. /FEA=mRNA /GEN=VIPR1 /PROD=vasoactive intestinal peptide receptor 1 /DB_XREF=gi:4759307 /UG=Hs.198726 vasoactive intestinal peptide receptor 1 /FL=gb:NM_004624.1 NM_004624 vasoactive intestinal peptide receptor 1 VIPR1 7433 NM_001251882 /// NM_001251883 /// NM_001251884 /// NM_001251885 /// NM_004624 /// XM_005265437 /// XM_005265438 /// XM_005265439 /// XM_005265440 /// XM_005265441 /// XM_006713323 0006936 // muscle contraction // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004999 // vasoactive intestinal polypeptide receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205020_s_at NM_005738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005738.1 /DEF=Homo sapiens ADP-ribosylation factor-like 4 (ARL4), mRNA. /FEA=mRNA /GEN=ARL4 /PROD=ADP-ribosylation factor-like 4 /DB_XREF=gi:5031602 /UG=Hs.201672 ADP-ribosylation factor-like 4 /FL=gb:U73960.1 gb:NM_005738.1 NM_005738 ADP-ribosylation factor-like 4A ARL4A 10124 NM_001037164 /// NM_001195396 /// NM_005738 /// NM_212460 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 205021_s_at AA860806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA860806 /FEA=EST /DB_XREF=gi:2952946 /DB_XREF=est:aj84a04.s1 /CLONE=IMAGE:1403118 /UG=Hs.211773 checkpoint suppressor 1 /FL=gb:U68723.1 gb:NM_005197.1 AA860806 forkhead box N3 FOXN3 1112 NM_001085471 /// NM_005197 0000077 // DNA damage checkpoint // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205022_s_at NM_005197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005197.1 /DEF=Homo sapiens checkpoint suppressor 1 (CHES1), mRNA. /FEA=mRNA /GEN=CHES1 /PROD=checkpoint suppressor 1 /DB_XREF=gi:4885136 /UG=Hs.211773 checkpoint suppressor 1 /FL=gb:U68723.1 gb:NM_005197.1 NM_005197 forkhead box N3 FOXN3 1112 NM_001085471 /// NM_005197 0000077 // DNA damage checkpoint // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205023_at D14134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D14134.1 /DEF=Human mRNA for RAD51, complete cds. /FEA=mRNA /GEN=Rad51 /PROD=RAD51 /DB_XREF=gi:285976 /UG=Hs.23044 RAD51 (S. cerevisiae) homolog (E coli RecA homolog) /FL=gb:D14134.1 gb:D13804.1 gb:NM_002875.1 D14134 RAD51 recombinase RAD51 5888 NM_001164269 /// NM_001164270 /// NM_002875 /// NM_133487 /// XM_006720626 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006312 // mitotic recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0009432 // SOS response // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0051106 // positive regulation of DNA ligation // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072757 // cellular response to camptothecin // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0000800 // lateral element // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043142 // single-stranded DNA-dependent ATPase activity // inferred from direct assay /// 0070182 // DNA polymerase binding // inferred from physical interaction 205024_s_at NM_002875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002875.1 /DEF=Homo sapiens RAD51 (S. cerevisiae) homolog (E coli RecA homolog) (RAD51), mRNA. /FEA=mRNA /GEN=RAD51 /PROD=RAD51 (S. cerevisiae) homolog (E coli RecAhomolog) /DB_XREF=gi:4506388 /UG=Hs.23044 RAD51 (S. cerevisiae) homolog (E coli RecA homolog) /FL=gb:D14134.1 gb:D13804.1 gb:NM_002875.1 NM_002875 RAD51 recombinase RAD51 5888 NM_001164269 /// NM_001164270 /// NM_002875 /// NM_133487 /// XM_006720626 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006312 // mitotic recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0009432 // SOS response // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0051106 // positive regulation of DNA ligation // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072757 // cellular response to camptothecin // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0000800 // lateral element // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043142 // single-stranded DNA-dependent ATPase activity // inferred from direct assay /// 0070182 // DNA polymerase binding // inferred from physical interaction 205025_at NM_005341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005341.1 /DEF=Homo sapiens GLI-Kruppel family member HKR3 (HKR3), mRNA. /FEA=mRNA /GEN=HKR3 /PROD=GLI-Kruppel family member HKR3 /DB_XREF=gi:4885418 /UG=Hs.2364 GLI-Kruppel family member HKR3 /FL=gb:L16896.1 gb:NM_005341.1 NM_005341 zinc finger and BTB domain containing 48 ZBTB48 3104 NM_001278647 /// NM_001278648 /// NM_005341 /// XM_006710591 /// XM_006710592 /// XR_426603 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205026_at NM_012448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012448.1 /DEF=Homo sapiens signal transducer and activator of transcription 5B (STAT5B), mRNA. /FEA=mRNA /GEN=STAT5B /PROD=signal transducer and activator of transcription5B /DB_XREF=gi:6912687 /UG=Hs.244613 signal transducer and activator of transcription 5B /FL=gb:U47686.1 gb:NM_012448.1 gb:U48730.2 NM_012448 signal transducer and activator of transcription 5B STAT5B 6777 NM_012448 /// XM_005257625 /// XM_005257626 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0001553 // luteinization // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042448 // progesterone metabolic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046543 // development of secondary female sexual characteristics // inferred from electronic annotation /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070669 // response to interleukin-2 // inferred from electronic annotation /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 0070672 // response to interleukin-15 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 205027_s_at NM_005204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005204.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 8 (MAP3K8), mRNA. /FEA=mRNA /GEN=MAP3K8 /PROD=mitogen-activated protein kinase kinase kinase8 /DB_XREF=gi:4885146 /UG=Hs.248 mitogen-activated protein kinase kinase kinase 8 /FL=gb:D14497.1 gb:NM_005204.1 NM_005204 mitogen-activated protein kinase kinase kinase 8 MAP3K8 1326 NM_001244134 /// NM_005204 /// XM_005252364 /// XM_005252366 /// XM_006717377 0000165 // MAPK cascade // not recorded /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // not recorded /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205028_at NM_016157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016157.1 /DEF=Homo sapiens trophinin (TRO), mRNA. /FEA=mRNA /GEN=TRO /PROD=KIAA1114 protein /DB_XREF=gi:7705565 /UG=Hs.259802 trophinin /FL=gb:AB029037.1 gb:NM_016157.1 NM_016157 trophinin TRO 7216 NM_001039705 /// NM_001271183 /// NM_001271184 /// NM_016157 /// NM_177556 /// NM_177557 /// NR_073148 /// NR_073149 /// XM_006724599 /// XM_006724600 /// XM_006724601 /// XM_006724602 /// XM_006724603 /// XM_006724604 /// XM_006724605 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 205029_s_at NM_001446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001446.1 /DEF=Homo sapiens fatty acid binding protein 7, brain (FABP7), mRNA. /FEA=mRNA /GEN=FABP7 /PROD=fatty acid binding protein 7, brain /DB_XREF=gi:4557584 /UG=Hs.26770 fatty acid binding protein 7, brain /FL=gb:D50373.1 gb:U51338.1 gb:D88648.1 gb:U81235.1 gb:NM_001446.1 NM_001446 fatty acid binding protein 7, brain FABP7 2173 NM_001446 /// XM_005266858 0001964 // startle response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0060134 // prepulse inhibition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 205030_at NM_001446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001446.1 /DEF=Homo sapiens fatty acid binding protein 7, brain (FABP7), mRNA. /FEA=mRNA /GEN=FABP7 /PROD=fatty acid binding protein 7, brain /DB_XREF=gi:4557584 /UG=Hs.26770 fatty acid binding protein 7, brain /FL=gb:D50373.1 gb:U51338.1 gb:D88648.1 gb:U81235.1 gb:NM_001446.1 NM_001446 fatty acid binding protein 7, brain FABP7 2173 NM_001446 /// XM_005266858 0001964 // startle response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0060134 // prepulse inhibition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 205031_at NM_001406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001406.1 /DEF=Homo sapiens ephrin-B3 (EFNB3), mRNA. /FEA=mRNA /GEN=EFNB3 /PROD=ephrin-B3 precursor /DB_XREF=gi:4503488 /UG=Hs.26988 ephrin-B3 /FL=gb:U62775.1 gb:U66406.1 gb:NM_001406.1 NM_001406 ephrin-B3 EFNB3 1949 NM_001406 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // not recorded /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016198 // axon choice point recognition // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0046875 // ephrin receptor binding // inferred from direct assay 205032_at NM_002203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002203.2 /DEF=Homo sapiens integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), mRNA. /FEA=mRNA /GEN=ITGA2 /PROD=integrin alpha 2 precursor /DB_XREF=gi:6006008 /UG=Hs.271986 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) /FL=gb:NM_002203.2 NM_002203 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) ITGA2 3673 NM_002203 /// NR_073103 /// NR_073104 /// NR_073105 /// NR_073106 /// NR_073107 0001666 // response to hypoxia // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006929 // substrate-dependent cell migration // inferred from mutant phenotype /// 0006971 // hypotonic response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031346 // positive regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033343 // positive regulation of collagen binding // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from mutant phenotype /// 0038065 // collagen-activated signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0038064 // collagen receptor activity // inferred from mutant phenotype /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205033_s_at NM_004084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004084.2 /DEF=Homo sapiens defensin, alpha 1, myeloid-related sequence (DEFA1), mRNA. /FEA=mRNA /GEN=DEFA1 /PROD=defensin, alpha 1, preproprotein /DB_XREF=gi:12621915 /UG=Hs.274463 defensin, alpha 1, myeloid-related sequence /FL=gb:NM_004084.2 gb:M21130.1 gb:M26602.1 NM_004084 defensin, alpha 1 /// defensin, alpha 1B /// defensin, alpha 3, neutrophil-specific DEFA1 /// DEFA1B /// DEFA3 1667 /// 1668 /// 728358 NM_001042500 /// NM_004084 /// NM_005217 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0035578 // azurophil granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 205034_at NM_004702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004702.1 /DEF=Homo sapiens cyclin E2 (CCNE2), mRNA. /FEA=mRNA /GEN=CCNE2 /PROD=cyclin E2 /DB_XREF=gi:4757931 /UG=Hs.30464 cyclin E2 /FL=gb:AF091433.1 gb:AF102778.1 gb:AF106690.1 gb:NM_004702.1 NM_004702 cyclin E2 CCNE2 9134 NM_004702 /// NM_057735 /// NM_057749 0000075 // cell cycle checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 205035_at NM_004715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004715.1 /DEF=Homo sapiens CTD (carboxy-terminal domina, RNA polymerase II, polypeptide A) phosphatase, subunit 1 (CTDP1), mRNA. /FEA=mRNA /GEN=CTDP1 /PROD=CTD (carboxy-terminal domina, RNA polymerase II,polypeptide A) phosphatase, subunit 1 /DB_XREF=gi:4758093 /UG=Hs.4076 CTD (carboxy-terminal domina, RNA polymerase II, polypeptide A) phosphatase, subunit 1 /FL=gb:AF081287.1 gb:NM_004715.1 gb:AF154115.1 NM_004715 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 CTDP1 9150 NM_001202504 /// NM_004715 /// NM_048368 /// XM_005266782 /// XM_006722574 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008420 // CTD phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 205036_at NM_007080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007080.1 /DEF=Homo sapiens Sm protein F (LSM6), mRNA. /FEA=mRNA /GEN=LSM6 /PROD=Sm protein F /DB_XREF=gi:5901997 /UG=Hs.42438 Sm protein F /FL=gb:NM_007080.1 gb:AF182292.1 NM_007080 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM6 11157 NM_007080 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 205037_at NM_006860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006860.2 /DEF=Homo sapiens putative GTP-binding protein similar to RAYRAB1C (RAYL), mRNA. /FEA=mRNA /GEN=RAYL /PROD=putative GTP-binding protein similar toRAYRAB1C /DB_XREF=gi:9257237 /UG=Hs.50267 putative GTP-binding protein similar to RAYRAB1C /FL=gb:BC000566.1 gb:NM_006860.2 NM_006860 intraflagellar transport 27 homolog (Chlamydomonas) IFT27 11020 NM_001177701 /// NM_001177702 /// NM_006860 /// NR_033531 /// XM_006724106 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 205038_at BG540504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG540504 /FEA=EST /DB_XREF=gi:13532737 /DB_XREF=est:602569230F1 /CLONE=IMAGE:4693783 /UG=Hs.54452 zinc finger protein, subfamily 1A, 1 (Ikaros) /FL=gb:U40462.1 gb:NM_006060.1 BG540504 IKAROS family zinc finger 1 (Ikaros) IKZF1 10320 NM_001220765 /// NM_001220766 /// NM_001220767 /// NM_001220768 /// NM_001220769 /// NM_001220770 /// NM_001220771 /// NM_001220772 /// NM_001220773 /// NM_001220774 /// NM_001220775 /// NM_001220776 /// NM_001291837 /// NM_001291838 /// NM_001291839 /// NM_001291840 /// NM_001291841 /// NM_001291842 /// NM_001291843 /// NM_001291844 /// NM_001291845 /// NM_001291846 /// NM_001291847 /// NM_006060 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045660 // positive regulation of neutrophil differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205039_s_at NM_006060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006060.1 /DEF=Homo sapiens zinc finger protein, subfamily 1A, 1 (Ikaros) (ZNFN1A1), mRNA. /FEA=mRNA /GEN=ZNFN1A1 /PROD=zinc finger protein, subfamily 1A, 1 (Ikaros) /DB_XREF=gi:5174500 /UG=Hs.54452 zinc finger protein, subfamily 1A, 1 (Ikaros) /FL=gb:U40462.1 gb:NM_006060.1 NM_006060 IKAROS family zinc finger 1 (Ikaros) IKZF1 10320 NM_001220765 /// NM_001220766 /// NM_001220767 /// NM_001220768 /// NM_001220769 /// NM_001220770 /// NM_001220771 /// NM_001220772 /// NM_001220773 /// NM_001220774 /// NM_001220775 /// NM_001220776 /// NM_001291837 /// NM_001291838 /// NM_001291839 /// NM_001291840 /// NM_001291841 /// NM_001291842 /// NM_001291843 /// NM_001291844 /// NM_001291845 /// NM_001291846 /// NM_001291847 /// NM_006060 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045660 // positive regulation of neutrophil differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205040_at NM_000607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000607.1 /DEF=Homo sapiens orosomucoid 1 (ORM1), mRNA. /FEA=mRNA /GEN=ORM1 /PROD=orosomucoid 1 precursor /DB_XREF=gi:9257231 /UG=Hs.572 orosomucoid 1 /FL=gb:M13692.1 gb:NM_000607.1 NM_000607 orosomucoid 1 ORM1 5004 NM_000607 0002682 // regulation of immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205041_s_at NM_000607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000607.1 /DEF=Homo sapiens orosomucoid 1 (ORM1), mRNA. /FEA=mRNA /GEN=ORM1 /PROD=orosomucoid 1 precursor /DB_XREF=gi:9257231 /UG=Hs.572 orosomucoid 1 /FL=gb:M13692.1 gb:NM_000607.1 NM_000607 orosomucoid 1 /// orosomucoid 2 ORM1 /// ORM2 5004 /// 5005 NM_000607 /// NM_000608 0002682 // regulation of immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205042_at NM_005476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005476.2 /DEF=Homo sapiens UDP-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase (GNE), mRNA. /FEA=mRNA /GEN=GNE /PROD=UDP-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase /DB_XREF=gi:6382074 /UG=Hs.5920 UDP-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase /FL=gb:AF051852.1 gb:AF155663.1 gb:NM_005476.2 NM_005476 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase GNE 10020 NM_001128227 /// NM_001190383 /// NM_001190384 /// NM_001190388 /// NM_005476 /// XM_005251334 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006045 // N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006054 // N-acetylneuraminate metabolic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046380 // N-acetylneuraminate biosynthetic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008761 // UDP-N-acetylglucosamine 2-epimerase activity // inferred from electronic annotation /// 0009384 // N-acylmannosamine kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205043_at NM_000492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000492.2 /DEF=Homo sapiens cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) (CFTR), mRNA. /FEA=mRNA /GEN=CFTR /PROD=cystic fibrosis transmembrane conductanceregulator, ATP-binding cassette (sub-family C, member 7) /DB_XREF=gi:6995995 /UG=Hs.663 cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) /FL=gb:NM_000492.2 NM_000492 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) CFTR 1080 NM_000492 /// XM_006715842 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0015705 // iodide transport // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // non-traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement /// 1902943 // positive regulation of voltage-gated chloride channel activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031205 // endoplasmic reticulum Sec complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005224 // ATP-binding and phosphorylation-dependent chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from direct assay /// 0005260 // channel-conductance-controlling ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 205044_at NM_014211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014211.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, pi (GABRP), mRNA. /FEA=mRNA /GEN=GABRP /PROD=gamma-aminobutyric acid (GABA) A receptor, pi /DB_XREF=gi:7657105 /UG=Hs.70725 gamma-aminobutyric acid (GABA) A receptor, pi /FL=gb:U95367.1 gb:NM_014211.1 NM_014211 gamma-aminobutyric acid (GABA) A receptor, pi GABRP 2568 NM_001291985 /// NM_014211 /// XM_005265872 /// XM_005265873 /// XM_005265874 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 205045_at NM_007202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007202.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 10 (AKAP10), mRNA. /FEA=mRNA /GEN=AKAP10 /PROD=A kinase (PRKA) anchor protein 10 /DB_XREF=gi:6005706 /UG=Hs.75456 A kinase (PRKA) anchor protein 10 /FL=gb:AF037439.1 gb:NM_007202.1 NM_007202 A kinase (PRKA) anchor protein 10 AKAP10 11216 NM_007202 /// XM_006721431 /// XM_006721432 /// XM_006721433 /// XR_243536 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation 205046_at NM_001813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001813.1 /DEF=Homo sapiens centromere protein E (312kD) (CENPE), mRNA. /FEA=mRNA /GEN=CENPE /PROD=centromere protein E /DB_XREF=gi:4502780 /UG=Hs.75573 centromere protein E (312kD) /FL=gb:NM_001813.1 NM_001813 centromere protein E, 312kDa CENPE 1062 NM_001286734 /// NM_001813 0000089 // mitotic metaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // traceable author statement /// 0007080 // mitotic metaphase plate congression // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // non-traceable author statement 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000778 // condensed nuclear chromosome kinetochore // inferred from electronic annotation /// 0000779 // condensed chromosome, centromeric region // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // traceable author statement /// 0005634 // nucleus // inferred from mutant phenotype /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0043515 // kinetochore binding // inferred from direct assay 205047_s_at NM_001673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001673.1 /DEF=Homo sapiens asparagine synthetase (ASNS), mRNA. /FEA=mRNA /GEN=ASNS /PROD=asparagine synthetase /DB_XREF=gi:4502258 /UG=Hs.75692 asparagine synthetase /FL=gb:M27396.1 gb:NM_001673.1 NM_001673 asparagine synthetase (glutamine-hydrolyzing) ASNS 440 NM_001178075 /// NM_001178076 /// NM_001178077 /// NM_001673 /// NM_133436 /// NM_183356 0001889 // liver development // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006529 // asparagine biosynthetic process // inferred by curator /// 0006529 // asparagine biosynthetic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from direct assay /// 0070981 // L-asparagine biosynthetic process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004066 // asparagine synthase (glutamine-hydrolyzing) activity // not recorded /// 0004066 // asparagine synthase (glutamine-hydrolyzing) activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205048_s_at NM_003832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003832.1 /DEF=Homo sapiens phosphoserine phosphatase-like (PSPHL), mRNA. /FEA=mRNA /GEN=PSPHL /PROD=L-3-phosphoserine phosphatase homolog /DB_XREF=gi:4502934 /UG=Hs.76845 phosphoserine phosphatase-like /FL=gb:NM_003832.1 NM_003832 phosphoserine phosphatase PSPH 5723 NM_004577 /// XM_005271773 /// XM_005271774 /// XM_005271775 /// XM_005271776 /// XM_005271777 /// XM_006715760 /// XM_006715761 0006563 // L-serine metabolic process // inferred from direct assay /// 0006564 // L-serine biosynthetic process // not recorded /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0004647 // phosphoserine phosphatase activity // inferred from direct assay /// 0004647 // phosphoserine phosphatase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205049_s_at NM_001783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001783.1 /DEF=Homo sapiens CD79A antigen (immunoglobulin-associated alpha) (CD79A), transcript variant 1, mRNA. /FEA=mRNA /GEN=CD79A /PROD=CD79A antigen, isoform 1 precursor /DB_XREF=gi:4502684 /UG=Hs.79630 CD79A antigen (immunoglobulin-associated alpha) /FL=gb:M80462.1 gb:M86921.1 gb:M74721.1 gb:NM_001783.1 NM_001783 CD79a molecule, immunoglobulin-associated alpha CD79A 973 NM_001783 /// NM_021601 0002376 // immune system process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019815 // B cell receptor complex // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from sequence or structural similarity 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205050_s_at NM_012324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012324.1 /DEF=Homo sapiens mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), mRNA. /FEA=mRNA /GEN=MAPK8IP2 /PROD=mitogen-activated protein kinase 8 interactingprotein 2 /DB_XREF=gi:6912491 /UG=Hs.80545 mitogen-activated protein kinase 8 interacting protein 2 /FL=gb:AF136382.1 gb:NM_012324.1 NM_012324 mitogen-activated protein kinase 8 interacting protein 2 MAPK8IP2 23542 NM_012324 /// NM_016431 /// NM_139124 0000165 // MAPK cascade // inferred from direct assay /// 0001662 // behavioral fear response // inferred from sequence or structural similarity /// 0007172 // signal complex assembly // traceable author statement /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007617 // mating behavior // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046958 // nonassociative learning // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // non-traceable author statement /// 0005078 // MAP-kinase scaffold activity // non-traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0032403 // protein complex binding // inferred from electronic annotation 205051_s_at NM_000222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000222.1 /DEF=Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), mRNA. /FEA=mRNA /GEN=KIT /PROD=v-kit Hardy-Zuckerman 4 feline sarcoma viraloncogene homolog precursor /DB_XREF=gi:4557694 /UG=Hs.81665 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog /FL=gb:NM_000222.1 NM_000222 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog KIT 3815 NM_000222 /// NM_001093772 /// XM_005265740 /// XM_005265741 /// XM_005265742 /// XM_006714038 0000187 // activation of MAPK activity // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002327 // immature B cell differentiation // inferred from sequence or structural similarity /// 0002371 // dendritic cell cytokine production // inferred from sequence or structural similarity /// 0002551 // mast cell chemotaxis // inferred from direct assay /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0009314 // response to radiation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // traceable author statement /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030318 // melanocyte differentiation // inferred from sequence or structural similarity /// 0030318 // melanocyte differentiation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032762 // mast cell cytokine production // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0038093 // Fc receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038109 // Kit signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043303 // mast cell degranulation // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060374 // mast cell differentiation // inferred from sequence or structural similarity /// 0060374 // mast cell differentiation // traceable author statement /// 0070662 // mast cell proliferation // traceable author statement /// 0097067 // cellular response to thyroid hormone stimulus // inferred from electronic annotation /// 0097324 // melanocyte migration // inferred from sequence or structural similarity /// 0097326 // melanocyte adhesion // inferred from sequence or structural similarity 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005020 // stem cell factor receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205052_at NM_001698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001698.1 /DEF=Homo sapiens AU RNA-binding proteinenoyl-Coenzyme A hydratase (AUH), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=AUH /PROD=AU RNA-binding proteinenoyl-Coenzyme Ahydratase precursor /DB_XREF=gi:4502326 /UG=Hs.81886 AU RNA-binding proteinenoyl-Coenzyme A hydratase /FL=gb:NM_001698.1 NM_001698 AU RNA binding protein/enoyl-CoA hydratase AUH 549 NM_001698 /// XM_005252066 /// XM_005252067 /// XM_005252068 /// XM_005252069 /// XM_005252071 /// XM_005252072 /// XM_005252073 /// XM_006717150 0006402 // mRNA catabolic process // inferred from direct assay /// 0006552 // leucine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from direct assay /// 0004490 // methylglutaconyl-CoA hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 205053_at NM_000946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000946.1 /DEF=Homo sapiens primase, polypeptide 1 (49kD) (PRIM1), mRNA. /FEA=mRNA /GEN=PRIM1 /PROD=primase, polypeptide 1 (49kD) /DB_XREF=gi:4506050 /UG=Hs.82741 primase, polypeptide 1 (49kD) /FL=gb:BC005266.1 gb:NM_000946.1 NM_000946 primase, DNA, polypeptide 1 (49kDa) PRIM1 5557 NM_000946 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006269 // DNA replication, synthesis of RNA primer // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 1990077 // primosome complex // inferred from electronic annotation 0003896 // DNA primase activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205054_at NM_004543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004543.2 /DEF=Homo sapiens nebulin (NEB), mRNA. /FEA=mRNA /GEN=NEB /PROD=nebulin /DB_XREF=gi:8400716 /UG=Hs.83870 nebulin /FL=gb:NM_004543.2 NM_004543 nebulin NEB 4703 NM_001164507 /// NM_001164508 /// NM_001271208 /// NM_004543 /// XM_005246590 /// XM_005246591 /// XM_005246592 /// XM_005246593 /// XM_005246594 /// XM_005246595 /// XM_005246596 /// XM_005246597 /// XM_005246598 /// XM_005246599 /// XM_005246600 /// XM_005246601 /// XM_005246602 /// XM_005246603 /// XM_005246604 /// XM_005246606 /// XM_005246608 /// XM_005246610 /// XM_005246611 /// XM_005246612 /// XM_005246613 /// XM_005246615 /// XM_005246616 /// XM_005246617 /// XM_005246618 /// XM_006712541 /// XM_006712542 0007517 // muscle organ development // traceable author statement /// 0007525 // somatic muscle development // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0030832 // regulation of actin filament length // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 205055_at NM_002208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002208.3 /DEF=Homo sapiens integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) (ITGAE), mRNA. /FEA=mRNA /GEN=ITGAE /PROD=integrin, alpha E (antigen CD103, human mucosallymphocyte antigen 1; alpha polypeptide) /DB_XREF=gi:6007850 /UG=Hs.851 integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) /FL=gb:L25851.2 gb:NM_002208.3 NM_002208 integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) ITGAE 3682 NM_002208 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 205056_s_at NM_019858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019858.1 /DEF=Homo sapiens protein A (A), transcript variant A-2, mRNA. /FEA=mRNA /GEN=A /PROD=protein A, isoform 2 /DB_XREF=gi:9951912 /UG=Hs.86122 protein A /FL=gb:U47928.1 gb:NM_019858.1 NM_019858 G protein-coupled receptor 162 GPR162 27239 NM_014449 /// NM_019858 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 205057_s_at AI762782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762782 /FEA=EST /DB_XREF=gi:5178449 /DB_XREF=est:wi04c05.x1 /CLONE=IMAGE:2389256 /UG=Hs.89560 iduronidase, alpha-L- /FL=gb:M74715.1 gb:NM_000203.1 AI762782 iduronidase, alpha-L- IDUA 3425 NM_000203 /// NR_110313 /// XM_006713881 /// XM_006713882 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005984 // disaccharide metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030209 // dermatan sulfate catabolic process // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048878 // chemical homeostasis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0030135 // coated vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003940 // L-iduronidase activity // inferred from direct assay /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 205058_at M74715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M74715.1 /DEF=Human alpha-L-iduronidas (IDUA) mRNA, complete cds. /FEA=mRNA /GEN=IDUA /PROD=alpha-L-iduronidase /DB_XREF=gi:184558 /UG=Hs.89560 iduronidase, alpha-L- /FL=gb:M74715.1 gb:NM_000203.1 M74715 solute carrier family 26 (anion exchanger), member 1 SLC26A1 10861 NM_022042 /// NM_134425 /// NM_213613 /// XM_006713856 /// XM_006713857 /// XM_006713858 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from sequence or structural similarity /// 0008272 // sulfate transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from sequence or structural similarity /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from sequence or structural similarity /// 0019531 // oxalate transmembrane transporter activity // inferred from sequence or structural similarity 205059_s_at NM_000203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000203.1 /DEF=Homo sapiens iduronidase, alpha-L- (IDUA), mRNA. /FEA=mRNA /GEN=IDUA /PROD=alpha-L-iduronidase precursor /DB_XREF=gi:4557660 /UG=Hs.89560 iduronidase, alpha-L- /FL=gb:M74715.1 gb:NM_000203.1 NM_000203 iduronidase, alpha-L- IDUA 3425 NM_000203 /// NR_110313 /// XM_006713881 /// XM_006713882 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005984 // disaccharide metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030209 // dermatan sulfate catabolic process // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048878 // chemical homeostasis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0030135 // coated vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003940 // L-iduronidase activity // inferred from direct assay /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 205060_at NM_003631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003631.1 /DEF=Homo sapiens poly (ADP-ribose) glycohydrolase (PARG), mRNA. /FEA=mRNA /GEN=PARG /PROD=poly (ADP-ribose) glycohydrolase /DB_XREF=gi:4505608 /UG=Hs.91390 poly (ADP-ribose) glycohydrolase /FL=gb:AF005043.1 gb:NM_003631.1 NM_003631 poly (ADP-ribose) glycohydrolase PARG 8505 NM_003631 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004649 // poly(ADP-ribose) glycohydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 205061_s_at NM_005033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005033.1 /DEF=Homo sapiens polymyositisscleroderma autoantigen 1 (75kD) (PMSCL1), mRNA. /FEA=mRNA /GEN=PMSCL1 /PROD=polymyositisscleroderma autoantigen 1 (75kD) /DB_XREF=gi:4826921 /UG=Hs.91728 polymyositisscleroderma autoantigen 1 (75kD) /FL=gb:M58460.1 gb:NM_005033.1 NM_005033 exosome component 9 EXOSC9 5393 NM_001034194 /// NM_005033 /// XR_427545 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006364 // rRNA processing // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071028 // nuclear mRNA surveillance // inferred from mutant phenotype /// 0071035 // nuclear polyadenylation-dependent rRNA catabolic process // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // non-traceable author statement 0000176 // nuclear exosome (RNase complex) // inferred from direct assay /// 0000176 // nuclear exosome (RNase complex) // non-traceable author statement /// 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 205062_x_at NM_002892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002892.2 /DEF=Homo sapiens retinoblastoma-binding protein 1 (RBBP1), transcript variant 1, mRNA. /FEA=mRNA /GEN=RBBP1 /PROD=retinoblastoma-binding protein 1, isoform I /DB_XREF=gi:13259496 /UG=Hs.91797 retinoblastoma-binding protein 1 /FL=gb:NM_002892.2 NM_002892 AT rich interactive domain 4A (RBP1-like) ARID4A 5926 NM_002892 /// NM_023000 /// NM_023001 /// XM_005267964 /// XM_005267965 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation /// 0036124 // histone H3-K9 trimethylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 205063_at NM_003616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003616.1 /DEF=Homo sapiens survival of motor neuron protein interacting protein 1 (SIP1), mRNA. /FEA=mRNA /GEN=SIP1 /PROD=survival of motor neuron protein interactingprotein 1 /DB_XREF=gi:4506960 /UG=Hs.102456 survival of motor neuron protein interacting protein 1 /FL=gb:AF027150.1 gb:NM_003616.1 NM_003616 gem (nuclear organelle) associated protein 2 GEMIN2 8487 NM_001009182 /// NM_001009183 /// NM_003616 0000245 // spliceosomal complex assembly // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205064_at NM_003125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003125.1 /DEF=Homo sapiens small proline-rich protein 1B (cornifin) (SPRR1B), mRNA. /FEA=mRNA /GEN=SPRR1B /PROD=small proline-rich protein 1B (cornifin) /DB_XREF=gi:4507186 /UG=Hs.1076 small proline-rich protein 1B (cornifin) /FL=gb:NM_003125.1 NM_003125 small proline-rich protein 1B SPRR1B 6699 NM_003125 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay 205065_at AU130282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU130282 /FEA=EST /DB_XREF=gi:10990636 /DB_XREF=est:AU130282 /CLONE=NT2RP3000545 /UG=Hs.11951 ectonucleotide pyrophosphatasephosphodiesterase 1 /FL=gb:NM_006208.1 gb:M57736.1 AU130282 ectonucleotide pyrophosphatase/phosphodiesterase 1 ENPP1 5167 NM_006208 /// XM_005267017 0006091 // generation of precursor metabolites and energy // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009143 // nucleoside triphosphate catabolic process // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred by curator /// 0030505 // inorganic diphosphate transport // inferred from direct assay /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0030730 // sequestering of triglyceride // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046849 // bone remodeling // inferred from electronic annotation /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // inferred from sequence or structural similarity /// 0004551 // nucleotide diphosphatase activity // inferred from direct assay /// 0004551 // nucleotide diphosphatase activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0035529 // NADH pyrophosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047429 // nucleoside-triphosphate diphosphatase activity // inferred from direct assay /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // inferred by curator 205066_s_at NM_006208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006208.1 /DEF=Homo sapiens ectonucleotide pyrophosphatasephosphodiesterase 1 (ENPP1), mRNA. /FEA=mRNA /GEN=ENPP1 /PROD=ectonucleotide pyrophosphatasephosphodiesterase1 /DB_XREF=gi:13324676 /UG=Hs.11951 ectonucleotide pyrophosphatasephosphodiesterase 1 /FL=gb:NM_006208.1 gb:M57736.1 NM_006208 ectonucleotide pyrophosphatase/phosphodiesterase 1 ENPP1 5167 NM_006208 /// XM_005267017 0006091 // generation of precursor metabolites and energy // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009143 // nucleoside triphosphate catabolic process // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred by curator /// 0030505 // inorganic diphosphate transport // inferred from direct assay /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0030730 // sequestering of triglyceride // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046849 // bone remodeling // inferred from electronic annotation /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // inferred from sequence or structural similarity /// 0004551 // nucleotide diphosphatase activity // inferred from direct assay /// 0004551 // nucleotide diphosphatase activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0035529 // NADH pyrophosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047429 // nucleoside-triphosphate diphosphatase activity // inferred from direct assay /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // inferred by curator 205067_at NM_000576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000576.1 /DEF=Homo sapiens interleukin 1, beta (IL1B), mRNA. /FEA=mRNA /GEN=IL1B /PROD=interleukin 1, beta /DB_XREF=gi:10835144 /UG=Hs.126256 interleukin 1, beta /FL=gb:NM_000576.1 gb:K02770.1 gb:M15330.1 gb:M54933.1 NM_000576 interleukin 1, beta IL1B 3553 NM_000576 /// XM_006712496 0000165 // MAPK cascade // inferred from mutant phenotype /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001660 // fever generation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // non-traceable author statement /// 0002711 // positive regulation of T cell mediated immunity // inferred by curator /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from sequence or structural similarity /// 0014805 // smooth muscle adaptation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030213 // hyaluronan biosynthetic process // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030730 // sequestering of triglyceride // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032308 // positive regulation of prostaglandin secretion // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // traceable author statement /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0033129 // positive regulation of histone phosphorylation // non-traceable author statement /// 0033198 // response to ATP // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // non-traceable author statement /// 0035066 // positive regulation of histone acetylation // non-traceable author statement /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0035505 // positive regulation of myosin light chain kinase activity // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045833 // negative regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // non-traceable author statement /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0050996 // positive regulation of lipid catabolic process // inferred from sequence or structural similarity /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060355 // positive regulation of cell adhesion molecule production // non-traceable author statement /// 0060559 // positive regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0070164 // negative regulation of adiponectin secretion // inferred from sequence or structural similarity /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071639 // positive regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from mutant phenotype /// 0005149 // interleukin-1 receptor binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction 205068_s_at BE671084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE671084 /FEA=EST /DB_XREF=gi:10031625 /DB_XREF=est:7e45g09.x1 /CLONE=IMAGE:3285472 /UG=Hs.132942 GTPase regulator associated with the focal adhesion kinase pp125(FAK); KIAA0621 protein /FL=gb:AF141884.1 gb:NM_015071.1 BE671084 Rho GTPase activating protein 26 ARHGAP26 23092 NM_001135608 /// NM_015071 /// XM_005268398 /// XM_005268399 /// XM_005268400 /// XM_005268402 /// XM_005268403 /// XM_006714768 /// XM_006714769 /// XM_006714770 /// XM_006714771 /// XM_006714772 /// XM_006714773 /// XM_006714774 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 205069_s_at NM_015071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015071.1 /DEF=Homo sapiens GTPase regulator associated with the focal adhesion kinase pp125(FAK); KIAA0621 protein (KIAA0621), mRNA. /FEA=mRNA /GEN=KIAA0621 /PROD=GTPase regulator associated with the focaladhesion kinase pp125(FAK); KIAA0621 protein /DB_XREF=gi:7662207 /UG=Hs.132942 GTPase regulator associated with the focal adhesion kinase pp125(FAK); KIAA0621 protein /FL=gb:AF141884.1 gb:NM_015071.1 NM_015071 Rho GTPase activating protein 26 ARHGAP26 23092 NM_001135608 /// NM_015071 /// XM_005268398 /// XM_005268399 /// XM_005268400 /// XM_005268402 /// XM_005268403 /// XM_006714768 /// XM_006714769 /// XM_006714770 /// XM_006714771 /// XM_006714772 /// XM_006714773 /// XM_006714774 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 205070_at NM_019071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019071.1 /DEF=Homo sapiens inhibitor of growth family, member 3 (ING3), mRNA. /FEA=mRNA /GEN=ING3 /PROD=inhibitor of growth family, member 3 /DB_XREF=gi:9506658 /UG=Hs.143198 inhibitor of growth family, member 3 /FL=gb:AF074968.1 gb:AY007790.1 gb:NM_019071.1 NM_019071 inhibitor of growth family, member 3 ING3 54556 NM_019071 /// NM_198266 /// NM_198267 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205071_x_at AB017445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017445.1 /DEF=Homo sapiens XRCC4 mRNA, complete cds. /FEA=mRNA /GEN=XRCC4 /DB_XREF=gi:12081904 /UG=Hs.150930 X-ray repair complementing defective repair in Chinese hamster cells 4 /FL=gb:U40622.1 gb:AB017445.1 gb:NM_003401.2 gb:NM_022406.1 AB017445 X-ray repair complementing defective repair in Chinese hamster cells 4 XRCC4 7518 NM_003401 /// NM_022406 /// NM_022550 /// XM_005248595 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // non-traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from direct assay /// 0051351 // positive regulation of ligase activity // inferred from direct assay /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032807 // DNA ligase IV complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from direct assay 205072_s_at NM_022406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022406.1 /DEF=Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 2, mRNA. /FEA=mRNA /GEN=XRCC4 /PROD=X-ray repair cross complementing protein 4,isoform 2 /DB_XREF=gi:12408646 /UG=Hs.150930 X-ray repair complementing defective repair in Chinese hamster cells 4 /FL=gb:U40622.1 gb:AB017445.1 gb:NM_003401.2 gb:NM_022406.1 NM_022406 X-ray repair complementing defective repair in Chinese hamster cells 4 XRCC4 7518 NM_003401 /// NM_022406 /// NM_022550 /// XM_005248595 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // non-traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from direct assay /// 0051351 // positive regulation of ligase activity // inferred from direct assay /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032807 // DNA ligase IV complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from direct assay 205073_at NM_000775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000775.1 /DEF=Homo sapiens cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2 (CYP2J2), mRNA. /FEA=mRNA /GEN=CYP2J2 /PROD=cytochrome P450, subfamily IIJ (arachidonic acidepoxygenase) polypeptide 2 /DB_XREF=gi:4503226 /UG=Hs.152096 cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2 /FL=gb:U37143.1 gb:NM_000775.1 NM_000775 cytochrome P450, family 2, subfamily J, polypeptide 2 CYP2J2 1573 NM_000775 /// XR_246240 0006690 // icosanoid metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0043651 // linoleic acid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0008404 // arachidonic acid 14,15-epoxygenase activity // inferred from direct assay /// 0008405 // arachidonic acid 11,12-epoxygenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation /// 0071614 // linoleic acid epoxygenase activity // inferred from direct assay 205074_at NM_003060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003060.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 5 (SLC22A5), mRNA. /FEA=mRNA /GEN=SLC22A5 /PROD=solute carrier family 22 (organic cationtransporter), member 5 /DB_XREF=gi:4507004 /UG=Hs.15813 solute carrier family 22 (organic cation transporter), member 5 /FL=gb:AB015050.1 gb:AF057164.1 gb:NM_003060.1 NM_003060 solute carrier family 22 (organic cation/carnitine transporter), member 5 SLC22A5 6584 NM_003060 /// XM_005272055 /// XM_006714676 /// XR_427718 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred by curator /// 0015697 // quaternary ammonium group transport // inferred from direct assay /// 0015879 // carnitine transport // inferred from direct assay /// 0015879 // carnitine transport // inferred from mutant phenotype /// 0015893 // drug transport // inferred by curator /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042891 // antibiotic transport // inferred from electronic annotation /// 0052106 // quorum sensing involved in interaction with host // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0060731 // positive regulation of intestinal epithelial structure maintenance // inferred from mutant phenotype /// 0070715 // sodium-dependent organic cation transport // inferred from direct assay /// 1902603 // carnitine transmembrane transport // inferred from direct assay /// 1902603 // carnitine transmembrane transport // inferred from electronic annotation /// 1902603 // carnitine transmembrane transport // inferred from mutant phenotype 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015226 // carnitine transmembrane transporter activity // inferred from direct assay /// 0015226 // carnitine transmembrane transporter activity // inferred from mutant phenotype /// 0015238 // drug transmembrane transporter activity // inferred by curator /// 0015293 // symporter activity // inferred from electronic annotation /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042895 // antibiotic transporter activity // inferred from electronic annotation 205075_at NM_000934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000934.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2), mRNA. /FEA=mRNA /GEN=SERPINF2 /PROD=serine (or cysteine) proteinase inhibitor, cladeF (alpha-2 antiplasmin, pigment epithelium derivedfactor), member 2 /DB_XREF=gi:11386142 /UG=Hs.159509 serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 /FL=gb:NM_000934.1 gb:D00174.1 NM_000934 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 SERPINF2 5345 NM_000934 /// NM_001165920 /// NM_001165921 /// XM_005256698 /// XM_005256699 /// XM_005256700 /// XM_005256701 /// XM_005256703 /// XM_006725255 0002034 // regulation of blood vessel size by renin-angiotensin // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0042730 // fibrinolysis // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 205076_s_at NM_006697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006697.1 /DEF=Homo sapiens cisplatin resistance associated (CRA), mRNA. /FEA=mRNA /GEN=CRA /PROD=cisplatin resistance associated /DB_XREF=gi:5870890 /UG=Hs.166066 cisplatin resistance associated /FL=gb:U78557.1 gb:NM_006697.1 NM_006697 myotubularin related protein 11 MTMR11 10903 NM_001145862 /// NM_006697 /// NM_181873 /// XM_006711135 /// XM_006711136 /// XM_006711137 /// XR_426759 /// XR_426760 0016311 // dephosphorylation // inferred from electronic annotation 0016791 // phosphatase activity // inferred from electronic annotation 205077_s_at NM_002643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002643.1 /DEF=Homo sapiens phosphatidylinositol glycan, class F (PIGF), mRNA. /FEA=mRNA /GEN=PIGF /PROD=phosphatidylinositol glycan, class F /DB_XREF=gi:4505796 /UG=Hs.166982 phosphatidylinositol glycan, class F /FL=gb:D13435.1 gb:NM_002643.1 NM_002643 phosphatidylinositol glycan anchor biosynthesis, class F PIGF 5281 NM_002643 /// NM_173074 /// XM_005264369 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004307 // ethanolaminephosphotransferase activity // traceable author statement 205078_at NM_002643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002643.1 /DEF=Homo sapiens phosphatidylinositol glycan, class F (PIGF), mRNA. /FEA=mRNA /GEN=PIGF /PROD=phosphatidylinositol glycan, class F /DB_XREF=gi:4505796 /UG=Hs.166982 phosphatidylinositol glycan, class F /FL=gb:D13435.1 gb:NM_002643.1 NM_002643 phosphatidylinositol glycan anchor biosynthesis, class F PIGF 5281 NM_002643 /// NM_173074 /// XM_005264369 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004307 // ethanolaminephosphotransferase activity // traceable author statement 205079_s_at NM_003829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003829.1 /DEF=Homo sapiens multiple PDZ domain protein (MPDZ), mRNA. /FEA=mRNA /GEN=MPDZ /PROD=multiple PDZ domain protein /DB_XREF=gi:4505230 /UG=Hs.169378 multiple PDZ domain protein /FL=gb:AF093419.1 gb:NM_003829.1 NM_003829 multiple PDZ domain protein MPDZ 8777 NM_001261406 /// NM_001261407 /// NM_003829 /// XM_005251622 /// XM_005251623 /// XM_006716885 /// XM_006716886 /// XM_006716887 /// XM_006716888 /// XM_006716889 /// XM_006716890 /// XM_006716891 /// XM_006716892 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 205080_at NM_000965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000965.1 /DEF=Homo sapiens retinoic acid receptor, beta (RARB), mRNA. /FEA=mRNA /GEN=RARB /PROD=retinoic acid receptor, beta /DB_XREF=gi:4506420 /UG=Hs.171495 retinoic acid receptor, beta /FL=gb:NM_000965.1 NM_000965 retinoic acid receptor, beta RARB 5915 NM_000965 /// NM_001290216 /// NM_001290217 /// NM_001290266 /// NM_001290276 /// NM_001290277 /// NM_001290300 /// NM_016152 /// NR_110892 /// NR_110893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021756 // striatum development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation 205081_at NM_001311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001311.1 /DEF=Homo sapiens cysteine-rich protein 1 (intestinal) (CRIP1), mRNA. /FEA=mRNA /GEN=CRIP1 /PROD=cysteine-rich protein 1 (intestinal) /DB_XREF=gi:4503046 /UG=Hs.17409 cysteine-rich protein 1 (intestinal) /FL=gb:BC002738.1 gb:U58630.1 gb:NM_001311.1 gb:U09770.1 NM_001311 cysteine-rich protein 1 (intestinal) CRIP1 1396 NM_001311 0006955 // immune response // inferred from expression pattern /// 0007507 // heart development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010033 // response to organic substance // inferred from expression pattern /// 0010043 // response to zinc ion // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from expression pattern /// 0060741 // prostate gland stromal morphogenesis // inferred from expression pattern /// 0071236 // cellular response to antibiotic // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0003680 // AT DNA binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0042277 // peptide binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205082_s_at AB046692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB046692.1 /DEF=Homo sapiens hAO mRNA for aldeyde oxidase, complete cds. /FEA=mRNA /GEN=hAO /PROD=aldeyde oxidase /DB_XREF=gi:13516378 /UG=Hs.174151 aldehyde oxidase 1 /FL=gb:AB046692.1 gb:L11005.1 gb:NM_001159.2 AB046692 aldehyde oxidase 1 AOX1 316 NM_001159 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004031 // aldehyde oxidase activity // traceable author statement /// 0004854 // xanthine dehydrogenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 205083_at NM_001159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001159.2 /DEF=Homo sapiens aldehyde oxidase 1 (AOX1), mRNA. /FEA=mRNA /GEN=AOX1 /PROD=aldehyde oxidase 1 /DB_XREF=gi:6598319 /UG=Hs.174151 aldehyde oxidase 1 /FL=gb:AB046692.1 gb:L11005.1 gb:NM_001159.2 NM_001159 aldehyde oxidase 1 AOX1 316 NM_001159 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004031 // aldehyde oxidase activity // traceable author statement /// 0004854 // xanthine dehydrogenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 205084_at NM_018844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018844.1 /DEF=Homo sapiens B-cell receptor-associated protein BAP29 (BAP29), mRNA. /FEA=mRNA /GEN=BAP29 /PROD=B-cell receptor-associated protein BAP29 /DB_XREF=gi:9994198 /UG=Hs.175941 B-cell receptor-associated protein BAP29 /FL=gb:AF126020.1 gb:NM_018844.1 NM_018844 B-cell receptor-associated protein 29 BCAP29 55973 NM_001008405 /// NM_001008406 /// NM_001008407 /// NM_018844 /// NR_027830 /// XM_006716051 0001649 // osteoblast differentiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 205085_at NM_004153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004153.1 /DEF=Homo sapiens origin recognition complex, subunit 1 (yeast homolog)-like (ORC1L), mRNA. /FEA=mRNA /GEN=ORC1L /PROD=origin recognition complex, subunit 1 (yeasthomolog)-like /DB_XREF=gi:4758849 /UG=Hs.17908 origin recognition complex, subunit 1 (yeast homolog)-like /FL=gb:U40152.1 gb:U43416.1 gb:NM_004153.1 NM_004153 origin recognition complex, subunit 1 ORC1 4998 NM_001190818 /// NM_001190819 /// NM_004153 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 205086_s_at NM_014551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014551.1 /DEF=Homo sapiens hypothetical protein 384D8_6 (384D8-2), mRNA. /FEA=mRNA /GEN=384D8-2 /PROD=hypothetical protein 384D8_6 /DB_XREF=gi:11024687 /UG=Hs.180903 hypothetical protein 384D8_6 /FL=gb:NM_014551.1 gb:BC001937.1 NM_014551 non-SMC condensin II complex, subunit H2 NCAPH2 29781 NM_001185011 /// NM_014551 /// NM_152299 /// XM_005261912 0000278 // mitotic cell cycle // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from direct assay 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205087_at NM_015485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015485.1 /DEF=Homo sapiens DKFZP566K023 protein (DKFZP566K023), mRNA. /FEA=mRNA /GEN=DKFZP566K023 /PROD=DKFZP566K023 protein /DB_XREF=gi:7661655 /UG=Hs.19999 DKFZP566K023 protein /FL=gb:NM_015485.1 NM_015485 RWD domain containing 3 RWDD3 25950 NM_001128142 /// NM_001199682 /// NM_001278247 /// NM_001278248 /// NM_015485 /// NR_103483 /// NR_103484 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 1902073 // positive regulation of hypoxia-inducible factor-1alpha signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205088_at NM_005491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005491.1 /DEF=Homo sapiens chromosome X open reading frame 6 (CXORF6), mRNA. /FEA=mRNA /GEN=CXORF6 /PROD=chromosome X open reading frame 6 /DB_XREF=gi:4885170 /UG=Hs.20136 chromosome X open reading frame 6 /FL=gb:U46023.1 gb:NM_005491.1 NM_005491 mastermind-like domain containing 1 MAMLD1 10046 NM_001177465 /// NM_001177466 /// NM_005491 /// XM_005274636 /// XM_006724802 /// XM_006724803 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation 205089_at NM_003416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003416.1 /DEF=Homo sapiens zinc finger protein 7 (KOX 4, clone HF.16) (ZNF7), mRNA. /FEA=mRNA /GEN=ZNF7 /PROD=zinc finger protein 7 (KOX 4, clone HF.16) /DB_XREF=gi:4508034 /UG=Hs.2076 zinc finger protein 7 (KOX 4, clone HF.16) /FL=gb:M29580.1 gb:NM_003416.1 NM_003416 zinc finger protein 7 ZNF7 7553 NM_001282795 /// NM_001282796 /// NM_001282797 /// NM_003416 /// XM_005272334 /// XM_006716653 /// XM_006716654 /// XM_006716655 /// XM_006716656 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205090_s_at NM_016256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016256.1 /DEF=Homo sapiens N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (LOC51172), mRNA. /FEA=mRNA /GEN=LOC51172 /PROD=N-acetylglucosamine-1-phosphodiesteralpha-N-acetylglucosaminidase /DB_XREF=gi:7705908 /UG=Hs.21334 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase /FL=gb:AF187072.1 gb:NM_016256.1 NM_016256 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase NAGPA 51172 NM_016256 /// XR_243285 /// XR_243286 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006622 // protein targeting to lysosome // traceable author statement /// 0007040 // lysosome organization // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003944 // N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205091_x_at NM_002907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002907.1 /DEF=Homo sapiens RecQ protein-like (DNA helicase Q1-like) (RECQL), mRNA. /FEA=mRNA /GEN=RECQL /PROD=RecQ protein-like (DNA helicase Q1-like) /DB_XREF=gi:4506468 /UG=Hs.235069 RecQ protein-like (DNA helicase Q1-like) /FL=gb:NM_002907.1 gb:L36140.1 NM_002907 RecQ helicase-like RECQL 5965 NM_002907 /// NM_032941 /// XM_005253461 /// XM_005253462 /// XM_005253463 /// XM_005253464 /// XM_006719133 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation 205092_x_at NM_014950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014950.1 /DEF=Homo sapiens KIAA0997 protein (KIAA0997), mRNA. /FEA=mRNA /GEN=KIAA0997 /PROD=KIAA0997 protein /DB_XREF=gi:7662437 /UG=Hs.24083 KIAA0997 protein /FL=gb:AB023214.1 gb:NM_014950.1 NM_014950 zinc finger and BTB domain containing 1 ZBTB1 22890 NM_001123329 /// NM_014950 /// XM_005267410 /// XM_005267411 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002711 // positive regulation of T cell mediated immunity // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from direct assay /// 2000176 // positive regulation of pro-T cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 205093_at NM_014935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014935.1 /DEF=Homo sapiens KIAA0969 protein (KIAA0969), mRNA. /FEA=mRNA /GEN=KIAA0969 /PROD=KIAA0969 protein /DB_XREF=gi:7662417 /UG=Hs.241161 KIAA0969 protein /FL=gb:AB023186.1 gb:NM_014935.1 NM_014935 pleckstrin homology domain containing, family A member 6 PLEKHA6 22874 NM_014935 /// NM_138480 /// XM_005244966 /// XM_005244967 /// XM_005244968 /// XM_006711212 /// XM_006711213 /// XM_006711214 /// XM_006711215 /// XM_006711216 /// XM_006711217 /// XM_006711218 /// XM_006711219 /// XM_006711220 /// XM_006711221 /// XM_006711222 /// XM_006711223 0005543 // phospholipid binding // inferred from electronic annotation 205094_at NM_000286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000286.1 /DEF=Homo sapiens peroxisomal biogenesis factor 12 (PEX12), mRNA. /FEA=mRNA /GEN=PEX12 /PROD=peroxisomal biogenesis factor 12 /DB_XREF=gi:4505720 /UG=Hs.25913 peroxisomal biogenesis factor 12 /FL=gb:AB004546.1 gb:U91521.1 gb:NM_000286.1 NM_000286 peroxisomal biogenesis factor 12 PEX12 5193 NM_000286 0006625 // protein targeting to peroxisome // non-traceable author statement /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // non-traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 205095_s_at NM_005177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005177.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110116kD) (ATP6N1A), mRNA. /FEA=mRNA /GEN=ATP6N1A /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) non-catalytic accessory protein 1A(110116kD) /DB_XREF=gi:4885084 /UG=Hs.267871 ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110116kD) /FL=gb:U73006.1 gb:NM_005177.1 NM_005177 ATPase, H+ transporting, lysosomal V0 subunit a1 ATP6V0A1 535 NM_001130020 /// NM_001130021 /// NM_005177 /// XM_005257459 /// XM_005257461 /// XM_005257463 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 205096_at NM_014833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014833.1 /DEF=Homo sapiens KIAA0618 gene product (KIAA0618), mRNA. /FEA=mRNA /GEN=KIAA0618 /PROD=KIAA0618 gene product /DB_XREF=gi:7662205 /UG=Hs.295112 KIAA0618 gene product /FL=gb:AB014518.1 gb:NM_014833.1 NM_014833 POM121 transmembrane nucleoporin POM121 9883 NM_001257190 /// NM_172020 /// XM_005250726 /// XM_005250727 /// XM_005250728 /// XM_005250729 /// XM_005250730 /// XM_005250731 /// XM_005250732 /// XM_006716194 /// XM_006716195 /// XM_006716196 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205097_at AI025519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI025519 /FEA=EST /DB_XREF=gi:3241132 /DB_XREF=est:ov75c04.x1 /CLONE=IMAGE:1643142 /UG=Hs.29981 solute carrier family 26 (sulfate transporter), member 2 /FL=gb:NM_000112.1 gb:U14528.1 AI025519 solute carrier family 26 (anion exchanger), member 2 SLC26A2 1836 NM_000112 0001503 // ossification // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0008272 // sulfate transport // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // traceable author statement 205098_at AI421071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI421071 /FEA=EST /DB_XREF=gi:4267002 /DB_XREF=est:tf24a02.x1 /CLONE=IMAGE:2097098 /UG=Hs.301921 chemokine (C-C motif) receptor 1 /FL=gb:L09230.1 gb:L10918.1 gb:NM_001295.1 AI421071 chemokine (C-C motif) receptor 1 CCR1 1230 NM_001295 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // non-traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0008152 // metabolic process // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0045672 // positive regulation of osteoclast differentiation // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016493 // C-C chemokine receptor activity // inferred from direct assay /// 0019957 // C-C chemokine binding // inferred from physical interaction /// 0035717 // chemokine (C-C motif) ligand 7 binding // inferred from physical interaction /// 0071791 // chemokine (C-C motif) ligand 5 binding // inferred from physical interaction 205099_s_at NM_001295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001295.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 1 (CCR1), mRNA. /FEA=mRNA /GEN=CCR1 /PROD=chemokine (C-C motif) receptor 1 /DB_XREF=gi:4502630 /UG=Hs.301921 chemokine (C-C motif) receptor 1 /FL=gb:L09230.1 gb:L10918.1 gb:NM_001295.1 NM_001295 chemokine (C-C motif) receptor 1 CCR1 1230 NM_001295 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // non-traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0008152 // metabolic process // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0045672 // positive regulation of osteoclast differentiation // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016493 // C-C chemokine receptor activity // inferred from direct assay /// 0019957 // C-C chemokine binding // inferred from physical interaction /// 0035717 // chemokine (C-C motif) ligand 7 binding // inferred from physical interaction /// 0071791 // chemokine (C-C motif) ligand 5 binding // inferred from physical interaction 205100_at NM_005110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005110.1 /DEF=Homo sapiens glutamine-fructose-6-phosphate transaminase 2 (GFPT2), mRNA. /FEA=mRNA /GEN=GFPT2 /PROD=glutamine-fructose-6-phosphate transaminase 2 /DB_XREF=gi:4826741 /UG=Hs.30332 glutamine-fructose-6-phosphate transaminase 2 /FL=gb:BC000012.1 gb:AB016789.1 gb:NM_005110.1 NM_005110 glutamine-fructose-6-phosphate transaminase 2 GFPT2 9945 NM_005110 /// XM_006714942 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // traceable author statement /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004360 // glutamine-fructose-6-phosphate transaminase (isomerizing) activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 205101_at NM_000246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000246.1 /DEF=Homo sapiens MHC class II transactivator (MHC2TA), mRNA. /FEA=mRNA /GEN=MHC2TA /PROD=MHC class II transactivator /DB_XREF=gi:4557748 /UG=Hs.3076 MHC class II transactivator /FL=gb:NM_000246.1 gb:U18259.1 NM_000246 class II, major histocompatibility complex, transactivator CIITA 4261 NM_000246 /// NM_001286402 /// NM_001286403 /// NR_104444 /// XM_005255320 /// XM_005255321 /// XM_005255323 /// XM_006720880 /// XM_006720881 /// XM_006720882 /// XM_006720883 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032966 // negative regulation of collagen biosynthetic process // inferred by curator /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0045345 // positive regulation of MHC class I biosynthetic process // inferred from direct assay /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 205102_at NM_005656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005656.1 /DEF=Homo sapiens transmembrane protease, serine 2 (TMPRSS2), mRNA. /FEA=mRNA /GEN=TMPRSS2 /PROD=transmembrane protease, serine 2 /DB_XREF=gi:5032184 /UG=Hs.318545 transmembrane protease, serine 2 /FL=gb:U75329.1 gb:AF123453.1 gb:NM_005656.1 NM_005656 transmembrane protease, serine 2 TMPRSS2 7113 NM_001135099 /// NM_005656 /// XM_005261042 /// XM_005261043 /// XM_005261044 /// XM_006724048 0006508 // proteolysis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from mutant phenotype /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205103_at NM_006365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006365.1 /DEF=Homo sapiens transcriptional activator of the c-fos promoter (CROC4), mRNA. /FEA=mRNA /GEN=CROC4 /PROD=transcriptional activator of the c-fos promoter /DB_XREF=gi:5453624 /UG=Hs.322469 transcriptional activator of the c-fos promoter /FL=gb:U49857.1 gb:NM_006365.1 NM_006365 chromosome 1 open reading frame 61 C1orf61 10485 NM_006365 /// XM_005244832 /// XM_006711117 /// XM_006711118 /// XM_006711119 /// XR_426755 0005634 // nucleus // inferred from electronic annotation 205104_at NM_014723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014723.1 /DEF=Homo sapiens syntaphilin (KIAA0374), mRNA. /FEA=mRNA /GEN=KIAA0374 /PROD=syntaphilin /DB_XREF=gi:7662081 /UG=Hs.323833 syntaphilin /FL=gb:AB002372.1 gb:AF187733.1 gb:NM_014723.1 NM_014723 syntaphilin SNPH 9751 NM_014723 /// XM_005260888 /// XM_005260889 /// XM_006723667 0007269 // neurotransmitter secretion // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016081 // synaptic vesicle docking involved in exocytosis // non-traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // non-traceable author statement 205105_at NM_002372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002372.1 /DEF=Homo sapiens mannosidase, alpha, class 2A, member 1 (MAN2A1), mRNA. /FEA=mRNA /GEN=MAN2A1 /PROD=mannosidase, alpha, class 2A, member 1 /DB_XREF=gi:4758697 /UG=Hs.32965 mannosidase, alpha, class 2A, member 1 /FL=gb:U31520.1 gb:NM_002372.1 gb:D63998.1 NM_002372 mannosidase, alpha, class 2A, member 1 MAN2A1 4124 NM_002372 /// XM_006714616 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007033 // vacuole organization // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0004572 // mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205106_at NM_014221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014221.1 /DEF=Homo sapiens mature T-cell proliferation 1 (MTCP1), mRNA. /FEA=mRNA /GEN=MTCP1 /PROD=mature T-cell proliferation 1 /DB_XREF=gi:7657348 /UG=Hs.3548 mature T-cell proliferation 1 /FL=gb:NM_014221.1 NM_014221 C-x(9)-C motif containing 4 /// mature T-cell proliferation 1 CMC4 /// MTCP1 4515 /// 100272147 NM_001018024 /// NM_001018025 /// NM_014221 0008283 // cell proliferation // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 205107_s_at NM_005227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005227.1 /DEF=Homo sapiens ephrin-A4 (EFNA4), mRNA. /FEA=mRNA /GEN=EFNA4 /PROD=ephrin-A4 /DB_XREF=gi:4885196 /UG=Hs.42331 ephrin-A4 /FL=gb:NM_005227.1 gb:U14188.1 NM_005227 ephrin-A4 EFNA4 1945 NM_005227 /// NM_182689 /// NM_182690 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // not recorded /// 0030316 // osteoclast differentiation // not recorded /// 0046849 // bone remodeling // not recorded /// 0048013 // ephrin receptor signaling pathway // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 205108_s_at NM_000384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000384.1 /DEF=Homo sapiens apolipoprotein B (including Ag(x) antigen) (APOB), mRNA. /FEA=mRNA /GEN=APOB /PROD=apolipoprotein B precursor /DB_XREF=gi:4502152 /UG=Hs.585 apolipoprotein B (including Ag(x) antigen) /FL=gb:J02610.1 gb:M14162.1 gb:NM_000384.1 NM_000384 apolipoprotein B APOB 338 NM_000384 0001523 // retinoid metabolic process // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006642 // triglyceride mobilization // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0009451 // RNA modification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010884 // positive regulation of lipid storage // inferred from direct assay /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0030317 // sperm motility // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034379 // very-low-density lipoprotein particle assembly // inferred by curator /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071379 // cellular response to prostaglandin stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0031983 // vesicle lumen // inferred from electronic annotation /// 0034359 // mature chylomicron // inferred from direct assay /// 0034360 // chylomicron remnant // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0071682 // endocytic vesicle lumen // traceable author statement 0005319 // lipid transporter activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0035473 // lipase binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from mutant phenotype 205109_s_at NM_015320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015320.1 /DEF=Homo sapiens Rho guanine nucleotide exchange factor (GEF) 4 (ARHGEF4), mRNA. /FEA=mRNA /GEN=ARHGEF4 /PROD=KIAA1112 protein /DB_XREF=gi:9558722 /UG=Hs.6066 Rho guanine nucleotide exchange factor (GEF) 4 /FL=gb:AF249745.1 gb:NM_015320.1 NM_015320 Rho guanine nucleotide exchange factor (GEF) 4 /// rho guanine nucleotide exchange factor 4-like ARHGEF4 /// LOC101930241 50649 /// 101930241 NM_015320 /// NM_032995 /// XM_005263681 /// XM_005263682 /// XM_005263683 /// XM_005263685 /// XM_005263686 /// XM_005263687 /// XM_005263688 /// XM_005263689 /// XM_005275931 /// XM_005275932 /// XM_005275933 /// XR_244821 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype 205110_s_at NM_004114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004114.1 /DEF=Homo sapiens fibroblast growth factor 13 (FGF13), mRNA. /FEA=mRNA /GEN=FGF13 /PROD=fibroblast growth factor 13 /DB_XREF=gi:4758365 /UG=Hs.6540 fibroblast growth factor 13 /FL=gb:U66198.1 gb:AF100143.1 gb:NM_004114.1 NM_004114 fibroblast growth factor 13 FGF13 2258 NM_001139498 /// NM_001139500 /// NM_001139501 /// NM_001139502 /// NM_004114 /// NM_033642 /// XM_005262399 0000165 // MAPK cascade // inferred from direct assay /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007026 // negative regulation of microtubule depolymerization // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007612 // learning // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021795 // cerebral cortex cell migration // inferred from sequence or structural similarity /// 0045200 // establishment of neuroblast polarity // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0046785 // microtubule polymerization // inferred from sequence or structural similarity /// 0048671 // negative regulation of collateral sprouting // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from physical interaction /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008083 // growth factor activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity 205111_s_at NM_016341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016341.1 /DEF=Homo sapiens pancreas-enriched phospholipase C (LOC51196), mRNA. /FEA=mRNA /GEN=LOC51196 /PROD=pancreas-enriched phospholipase C /DB_XREF=gi:7705940 /UG=Hs.6733 pancreas-enriched phospholipase C /FL=gb:AF190642.2 gb:AF117948.1 gb:NM_016341.1 NM_016341 phospholipase C, epsilon 1 PLCE1 51196 NM_001165979 /// NM_001288989 /// NM_016341 /// XM_006717885 /// XM_006717886 /// XM_006717887 /// XM_006717888 /// XM_006717889 /// XM_006717890 0000187 // activation of MAPK activity // inferred from direct assay /// 0001558 // regulation of cell growth // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred by curator /// 0006651 // diacylglycerol biosynthetic process // traceable author statement /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007507 // heart development // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0032835 // glomerulus development // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046578 // regulation of Ras protein signal transduction // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004629 // phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 205112_at NM_016341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016341.1 /DEF=Homo sapiens pancreas-enriched phospholipase C (LOC51196), mRNA. /FEA=mRNA /GEN=LOC51196 /PROD=pancreas-enriched phospholipase C /DB_XREF=gi:7705940 /UG=Hs.6733 pancreas-enriched phospholipase C /FL=gb:AF190642.2 gb:AF117948.1 gb:NM_016341.1 NM_016341 phospholipase C, epsilon 1 PLCE1 51196 NM_001165979 /// NM_001288989 /// NM_016341 /// XM_006717885 /// XM_006717886 /// XM_006717887 /// XM_006717888 /// XM_006717889 /// XM_006717890 0000187 // activation of MAPK activity // inferred from direct assay /// 0001558 // regulation of cell growth // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred by curator /// 0006651 // diacylglycerol biosynthetic process // traceable author statement /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007507 // heart development // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0032835 // glomerulus development // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046578 // regulation of Ras protein signal transduction // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004629 // phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 205113_at NM_005382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005382.1 /DEF=Homo sapiens neurofilament 3 (150kD medium) (NEF3), mRNA. /FEA=mRNA /GEN=NEF3 /PROD=neurofilament 3 (150kD medium) /DB_XREF=gi:4885512 /UG=Hs.71346 neurofilament 3 (150kD medium) /FL=gb:NM_005382.1 NM_005382 neurofilament, medium polypeptide NEFM 4741 NM_001105541 /// NM_005382 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0031133 // regulation of axon diameter // inferred from electronic annotation /// 0033693 // neurofilament bundle assembly // traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // inferred from electronic annotation /// 0030424 // axon // traceable author statement /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0097418 // neurofibrillary tangle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement 205114_s_at NM_002983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002983.1 /DEF=Homo sapiens small inducible cytokine A3 (homologous to mouse Mip-1a) (SCYA3), mRNA. /FEA=mRNA /GEN=SCYA3 /PROD=small inducible cytokine A3 (homologous to mouseMip-1a) /DB_XREF=gi:4506842 /UG=Hs.73817 small inducible cytokine A3 (homologous to mouse Mip-1a) /FL=gb:M23452.1 gb:D00044.1 gb:NM_002983.1 gb:M25315.1 NM_002983 chemokine (C-C motif) ligand 3 /// chemokine (C-C motif) ligand 3-like 1 /// chemokine (C-C motif) ligand 3-like 3 CCL3 /// CCL3L1 /// CCL3L3 6348 /// 6349 /// 414062 NM_001001437 /// NM_002983 /// NM_021006 /// NR_111964 /// XM_006725571 0000165 // MAPK cascade // inferred from expression pattern /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // inferred from direct assay /// 0006954 // inflammatory response // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007610 // behavior // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009636 // response to toxic substance // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010818 // T cell chemotaxis // inferred from direct assay /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0023052 // signaling // inferred from expression pattern /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043308 // eosinophil degranulation // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043615 // astrocyte cell migration // inferred from sequence or structural similarity /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from sequence or structural similarity /// 0048247 // lymphocyte chemotaxis // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0050850 // positive regulation of calcium-mediated signaling // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from expression pattern /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070723 // response to cholesterol // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071621 // granulocyte chemotaxis // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // traceable author statement /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0004698 // calcium-dependent protein kinase C activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 205115_s_at NM_016196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016196.1 /DEF=Homo sapiens hypothetical protein (DKFZp586F1023), mRNA. /FEA=mRNA /GEN=DKFZp586F1023 /PROD=hypothetical protein /DB_XREF=gi:7705364 /UG=Hs.7482 hypothetical protein /FL=gb:AL117547.1 gb:NM_016196.1 NM_016196 RNA binding motif protein 19 RBM19 9904 NM_001146698 /// NM_001146699 /// NM_016196 0007275 // multicellular organismal development // inferred from electronic annotation /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205116_at NM_000426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000426.1 /DEF=Homo sapiens laminin, alpha 2 (merosin, congenital muscular dystrophy) (LAMA2), mRNA. /FEA=mRNA /GEN=LAMA2 /PROD=laminin alpha 2 subunit precursor /DB_XREF=gi:4557708 /UG=Hs.75279 laminin, alpha 2 (merosin, congenital muscular dystrophy) /FL=gb:NM_000426.1 NM_000426 laminin, alpha 2 LAMA2 3908 NM_000426 /// NM_001079823 /// XM_005266981 /// XM_005266982 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 205117_at X59065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X59065 /DEF=H.sapiens FGF gene, exon 3 /FEA=mRNA /DB_XREF=gi:31359 /UG=Hs.75297 fibroblast growth factor 1 (acidic) /FL=gb:M13361.1 gb:NM_000800.1 X59065 fibroblast growth factor 1 (acidic) FGF1 2246 NM_000800 /// NM_001144892 /// NM_001144934 /// NM_001144935 /// NM_001257205 /// NM_001257206 /// NM_001257207 /// NM_001257208 /// NM_001257209 /// NM_001257210 /// NM_001257211 /// NM_001257212 /// NM_033136 /// NM_033137 /// XM_005268390 /// XM_006714762 0001525 // angiogenesis // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from direct assay /// 0060681 // branch elongation involved in ureteric bud branching // inferred from direct assay /// 0072163 // mesonephric epithelium development // inferred from direct assay /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0044548 // S100 protein binding // inferred from physical interaction 205118_at M60626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60626.1 /DEF=Human N-formylpeptide receptor (fMLP-R98) mRNA, complete cds. /FEA=mRNA /PROD=N-formylpeptide receptor fMLP-R98 /DB_XREF=gi:182662 /UG=Hs.753 formyl peptide receptor 1 /FL=gb:BC005315.1 gb:M60626.1 gb:M60627.1 gb:NM_002029.1 M60626 formyl peptide receptor 1 FPR1 2357 NM_001193306 /// NM_002029 0000187 // activation of MAPK activity // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // traceable author statement 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0050786 // RAGE receptor binding // inferred from electronic annotation 205119_s_at NM_002029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002029.1 /DEF=Homo sapiens formyl peptide receptor 1 (FPR1), mRNA. /FEA=mRNA /GEN=FPR1 /PROD=formyl peptide receptor 1 /DB_XREF=gi:4503778 /UG=Hs.753 formyl peptide receptor 1 /FL=gb:BC005315.1 gb:M60626.1 gb:M60627.1 gb:NM_002029.1 NM_002029 formyl peptide receptor 1 FPR1 2357 NM_001193306 /// NM_002029 0000187 // activation of MAPK activity // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // traceable author statement 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0050786 // RAGE receptor binding // inferred from electronic annotation 205120_s_at U29586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U29586.1 /DEF=Human beta-sarcoglycan dystrophin-associated glycoprotein mRNA, complete cds. /FEA=mRNA /PROD=dystrophin-associated glycoprotein /DB_XREF=gi:1794188 /UG=Hs.77501 sarcoglycan, beta (43kD dystrophin-associated glycoprotein) /FL=gb:U31116.1 gb:U29586.1 gb:NM_000232.1 U29586 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) SGCB 6443 NM_000232 /// XM_006714046 /// XM_006714047 /// XM_006714048 /// XM_006714049 0007517 // muscle organ development // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 205121_at NM_000232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000232.1 /DEF=Homo sapiens sarcoglycan, beta (43kD dystrophin-associated glycoprotein) (SGCB), mRNA. /FEA=mRNA /GEN=SGCB /PROD=sarcoglycan, beta (43kD dystrophin-associatedglycoprotein) /DB_XREF=gi:4506912 /UG=Hs.77501 sarcoglycan, beta (43kD dystrophin-associated glycoprotein) /FL=gb:U31116.1 gb:U29586.1 gb:NM_000232.1 NM_000232 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) SGCB 6443 NM_000232 /// XM_006714046 /// XM_006714047 /// XM_006714048 /// XM_006714049 0007517 // muscle organ development // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 205122_at BF439316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439316 /FEA=EST /DB_XREF=gi:11451833 /DB_XREF=est:nab62g12.x1 /CLONE=IMAGE:3272638 /UG=Hs.78531 transmembrane protein with EGF-like and two follistatin-like domains 1 /FL=gb:NM_003692.1 gb:U19878.1 BF439316 MSANTD3-TMEFF1 readthrough /// transmembrane protein with EGF-like and two follistatin-like domains 1 MSANTD3-TMEFF1 /// TMEFF1 8577 /// 100526694 NM_001198812 /// NM_003692 0007275 // multicellular organismal development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205123_s_at NM_003692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003692.1 /DEF=Homo sapiens transmembrane protein with EGF-like and two follistatin-like domains 1 (TMEFF1), mRNA. /FEA=mRNA /GEN=TMEFF1 /PROD=transmembrane protein with EGF-like and twofollistatin-like domains 1 /DB_XREF=gi:4507548 /UG=Hs.78531 transmembrane protein with EGF-like and two follistatin-like domains 1 /FL=gb:NM_003692.1 gb:U19878.1 NM_003692 MSANTD3-TMEFF1 readthrough /// transmembrane protein with EGF-like and two follistatin-like domains 1 MSANTD3-TMEFF1 /// TMEFF1 8577 /// 100526694 NM_001198812 /// NM_003692 0007275 // multicellular organismal development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205124_at NM_005919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005919.1 /DEF=Homo sapiens MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) (MEF2B), mRNA. /FEA=mRNA /GEN=MEF2B /PROD=MADS box transcription enhancer factor 2,polypeptide B (myocyte enhancer factor 2B) /DB_XREF=gi:5174542 /UG=Hs.78881 MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) /FL=gb:NM_005919.1 NM_005919 myocyte enhancer factor 2B /// MEF2B neighbor /// MEF2BNB-MEF2B readthrough MEF2B /// MEF2BNB /// MEF2BNB-MEF2B 4207 /// 729991 /// 100271849 NM_001145783 /// NM_001145784 /// NM_001145785 /// NM_005919 /// NR_027307 /// NR_027308 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern /// 0007517 // muscle organ development // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 205125_at NM_006225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006225.1 /DEF=Homo sapiens phospholipase C, delta 1 (PLCD1), mRNA. /FEA=mRNA /GEN=PLCD1 /PROD=phospholipase C, delta 1 /DB_XREF=gi:5453909 /UG=Hs.80776 phospholipase C, delta 1 /FL=gb:U09117.1 gb:NM_006225.1 NM_006225 phospholipase C, delta 1 PLCD1 5333 NM_001130964 /// NM_006225 /// NR_024071 0001525 // angiogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205126_at NM_006296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006296.1 /DEF=Homo sapiens vaccinia related kinase 2 (VRK2), mRNA. /FEA=mRNA /GEN=VRK2 /PROD=vaccinia related kinase 2 /DB_XREF=gi:5454163 /UG=Hs.82771 vaccinia related kinase 2 /FL=gb:AB000450.1 gb:NM_006296.1 NM_006296 vaccinia related kinase 2 VRK2 7444 NM_001130480 /// NM_001130481 /// NM_001130482 /// NM_001130483 /// NM_001288836 /// NM_001288837 /// NM_001288838 /// NM_001288839 /// NM_006296 /// XM_005264540 /// XM_005264541 /// XM_006712090 /// XM_006712091 /// XM_006712092 /// XM_006712093 0006468 // protein phosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 2000659 // regulation of interleukin-1-mediated signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205127_at NM_000962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000962.1 /DEF=Homo sapiens prostaglandin-endoperoxide synthase 1 (prostaglandin GH synthase and cyclooxygenase) (PTGS1), mRNA. /FEA=mRNA /GEN=PTGS1 /PROD=prostaglandin-endoperoxide synthase 1(prostaglandin GH synthase and cyclooxygenase) /DB_XREF=gi:11386140 /UG=Hs.88474 prostaglandin-endoperoxide synthase 1 (prostaglandin GH synthase and cyclooxygenase) /FL=gb:NM_000962.1 gb:M59979.1 NM_000962 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) PTGS1 5742 NM_000962 /// NM_001271164 /// NM_001271165 /// NM_001271166 /// NM_001271367 /// NM_001271368 /// NM_080591 /// XM_005252105 /// XM_006717192 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // inferred from direct assay /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004601 // peroxidase activity // traceable author statement /// 0004666 // prostaglandin-endoperoxide synthase activity // inferred from direct assay /// 0004666 // prostaglandin-endoperoxide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205128_x_at NM_000962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000962.1 /DEF=Homo sapiens prostaglandin-endoperoxide synthase 1 (prostaglandin GH synthase and cyclooxygenase) (PTGS1), mRNA. /FEA=mRNA /GEN=PTGS1 /PROD=prostaglandin-endoperoxide synthase 1(prostaglandin GH synthase and cyclooxygenase) /DB_XREF=gi:11386140 /UG=Hs.88474 prostaglandin-endoperoxide synthase 1 (prostaglandin GH synthase and cyclooxygenase) /FL=gb:NM_000962.1 gb:M59979.1 NM_000962 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) PTGS1 5742 NM_000962 /// NM_001271164 /// NM_001271165 /// NM_001271166 /// NM_001271367 /// NM_001271368 /// NM_080591 /// XM_005252105 /// XM_006717192 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // inferred from direct assay /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004601 // peroxidase activity // traceable author statement /// 0004666 // prostaglandin-endoperoxide synthase activity // inferred from direct assay /// 0004666 // prostaglandin-endoperoxide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205129_at NM_006993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006993.1 /DEF=Homo sapiens nucleophosminnucleoplasmin 3 (NPM3), mRNA. /FEA=mRNA /GEN=NPM3 /PROD=nucleophosminnucleoplasmin 3 /DB_XREF=gi:6857817 /UG=Hs.90691 nucleophosminnucleoplasmin 3 /FL=gb:AF081280.1 gb:NM_006993.1 NM_006993 nucleophosmin/nucleoplasmin 3 NPM3 10360 NM_006993 0006364 // rRNA processing // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 205130_at NM_014226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014226.1 /DEF=Homo sapiens renal tumor antigen (RAGE), mRNA. /FEA=mRNA /GEN=RAGE /PROD=renal tumor antigen /DB_XREF=gi:7657497 /UG=Hs.104119 renal tumor antigen /FL=gb:AB022694.1 gb:NM_014226.1 NM_014226 MOK protein kinase MOK 5891 NM_001272011 /// NM_014226 /// NR_073540 /// NR_073541 /// NR_073542 /// NR_073543 /// XM_006720225 /// XM_006720226 /// XM_006720227 /// XM_006720228 /// XR_429320 /// XR_429321 /// XR_429322 /// XR_429323 /// XR_429324 /// XR_429325 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205131_x_at NM_002975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002975.1 /DEF=Homo sapiens stem cell growth factor; lymphocyte secreted C-type lectin (SCGF), mRNA. /FEA=mRNA /GEN=SCGF /PROD=stem cell growth factor; lymphocyte secretedC-type lectin /DB_XREF=gi:4506802 /UG=Hs.105927 stem cell growth factor; lymphocyte secreted C-type lectin /FL=gb:AF020044.1 gb:AB009244.1 gb:NM_002975.1 NM_002975 C-type lectin domain family 11, member A CLEC11A 6320 NM_002975 0008284 // positive regulation of cell proliferation // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0008083 // growth factor activity // inferred from direct assay /// 0030246 // carbohydrate binding // non-traceable author statement 205132_at NM_005159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005159.2 /DEF=Homo sapiens actin, alpha, cardiac muscle (ACTC), mRNA. /FEA=mRNA /GEN=ACTC /PROD=actin, alpha, cardiac muscle precursor /DB_XREF=gi:10938011 /UG=Hs.118127 actin, alpha, cardiac muscle /FL=gb:NM_005159.2 NM_005159 actin, alpha, cardiac muscle 1 ACTC1 70 NM_005159 0006200 // ATP catabolic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030240 // skeletal muscle thin filament assembly // inferred from sequence or structural similarity /// 0031032 // actomyosin structure organization // inferred from sequence or structural similarity /// 0033275 // actin-myosin filament sliding // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030017 // sarcomere // inferred from direct assay /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0031674 // I band // inferred from sequence or structural similarity /// 0042643 // actomyosin, actin portion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0017022 // myosin binding // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction 205133_s_at NM_002157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002157.1 /DEF=Homo sapiens heat shock 10kD protein 1 (chaperonin 10) (HSPE1), mRNA. /FEA=mRNA /GEN=HSPE1 /PROD=heat shock 10kD protein 1 (chaperonin 10) /DB_XREF=gi:4504522 /UG=Hs.1197 heat shock 10kD protein 1 (chaperonin 10) /FL=gb:NM_002157.1 gb:U07550.1 NM_002157 heat shock 10kDa protein 1 HSPE1 3336 NM_002157 0001649 // osteoblast differentiation // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from sequence or structural similarity 205134_s_at AW593143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW593143 /FEA=EST /DB_XREF=gi:7280401 /DB_XREF=est:hg09f10.x1 /CLONE=IMAGE:2945131 /UG=Hs.120247 nuclear fragile X mental retardation protein interacting protein 1 /FL=gb:AF159548.1 gb:NM_012345.1 AW593143 nuclear fragile X mental retardation protein interacting protein 1 NUFIP1 26747 NM_012345 0000492 // box C/D snoRNP assembly // inferred from mutant phenotype /// 0006396 // RNA processing // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005726 // perichromatin fibrils // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0022626 // cytosolic ribosome // inferred from direct assay /// 0048786 // presynaptic active zone // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205135_s_at AL049842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049842 /DEF=Human DNA sequence from clone 129L7 on chromosome 6q12-13. Contains the gene for a PUTATIVE novel protein, ESTs, an STS, GSSs and a taga repeat polymorphism /FEA=mRNA /DB_XREF=gi:5419768 /UG=Hs.120247 nuclear fragile X mental retardation protein interacting protein 1 /FL=gb:AF159548.1 gb:NM_012345.1 AL049842 nuclear fragile X mental retardation protein interacting protein 1 NUFIP1 26747 NM_012345 0000492 // box C/D snoRNP assembly // inferred from mutant phenotype /// 0006396 // RNA processing // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005726 // perichromatin fibrils // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0022626 // cytosolic ribosome // inferred from direct assay /// 0048786 // presynaptic active zone // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205136_s_at NM_012345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012345.1 /DEF=Homo sapiens nuclear fragile X mental retardation protein interacting protein 1 (NUFIP1), mRNA. /FEA=mRNA /GEN=NUFIP1 /PROD=nuclear fragile X mental retardation proteininteracting protein 1 /DB_XREF=gi:6912541 /UG=Hs.120247 nuclear fragile X mental retardation protein interacting protein 1 /FL=gb:AF159548.1 gb:NM_012345.1 NM_012345 nuclear fragile X mental retardation protein interacting protein 1 NUFIP1 26747 NM_012345 0000492 // box C/D snoRNP assembly // inferred from mutant phenotype /// 0006396 // RNA processing // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005726 // perichromatin fibrils // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0022626 // cytosolic ribosome // inferred from direct assay /// 0048786 // presynaptic active zone // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205137_x_at NM_005709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005709.1 /DEF=Homo sapiens PDZ-73 protein (PDZ-73NY-CO-38), mRNA. /FEA=mRNA /GEN=PDZ-73NY-CO-38 /PROD=PDZ-73 protein /DB_XREF=gi:5031978 /UG=Hs.132945 PDZ-73 protein /FL=gb:AF039700.1 gb:NM_005709.1 gb:AB018687.1 NM_005709 Usher syndrome 1C (autosomal recessive, severe) USH1C 10083 NM_005709 /// NM_153676 /// XM_005252725 /// XM_006718119 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0030046 // parallel actin filament bundle assembly // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // traceable author statement /// 0045177 // apical part of cell // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 205138_s_at AW418882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW418882 /FEA=EST /DB_XREF=gi:6946814 /DB_XREF=est:ha15a06.x1 /CLONE=IMAGE:2873746 /UG=Hs.134015 uronyl 2-sulfotransferase /FL=gb:AB020316.1 gb:NM_005715.1 AW418882 uronyl-2-sulfotransferase UST 10090 NM_005715 /// XM_005266790 0005975 // carbohydrate metabolic process // traceable author statement /// 0006477 // protein sulfation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001733 // galactosylceramide sulfotransferase activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205139_s_at NM_005715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005715.1 /DEF=Homo sapiens uronyl 2-sulfotransferase (UST), mRNA. /FEA=mRNA /GEN=UST /PROD=uronyl 2-sulfotransferase /DB_XREF=gi:5032218 /UG=Hs.134015 uronyl 2-sulfotransferase /FL=gb:AB020316.1 gb:NM_005715.1 NM_005715 uronyl-2-sulfotransferase UST 10090 NM_005715 /// XM_005266790 0005975 // carbohydrate metabolic process // traceable author statement /// 0006477 // protein sulfation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001733 // galactosylceramide sulfotransferase activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205140_at NM_003838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003838.1 /DEF=Homo sapiens fucose-1-phosphate guanylyltransferase (FPGT), mRNA. /FEA=mRNA /GEN=FPGT /PROD=fucose-1-phosphate guanyltransferase /DB_XREF=gi:4503776 /UG=Hs.150926 fucose-1-phosphate guanylyltransferase /FL=gb:AF017445.1 gb:NM_003838.1 NM_003838 fucose-1-phosphate guanylyltransferase FPGT 8790 NM_001199328 /// NM_001199329 /// NM_003838 0006004 // fucose metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031013 // troponin I binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047341 // fucose-1-phosphate guanylyltransferase activity // inferred from electronic annotation 205141_at NM_001145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001145.1 /DEF=Homo sapiens angiogenin, ribonuclease, RNase A family, 5 (ANG), mRNA. /FEA=mRNA /GEN=ANG /PROD=angiogenin, ribonuclease, RNase A family, 5precursor /DB_XREF=gi:4557312 /UG=Hs.154730 angiogenin, ribonuclease, RNase A family, 5 /FL=gb:NM_001145.1 NM_001145 angiogenin, ribonuclease, RNase A family, 5 ANG 283 NM_001097577 /// NM_001145 0001525 // angiogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // traceable author statement /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001556 // oocyte maturation // non-traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // non-traceable author statement /// 0001890 // placenta development // non-traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006379 // mRNA cleavage // non-traceable author statement /// 0006651 // diacylglycerol biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from mutant phenotype /// 0009725 // response to hormone // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032148 // activation of protein kinase B activity // inferred from mutant phenotype /// 0032431 // activation of phospholipase A2 activity // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042592 // homeostatic process // non-traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032311 // angiogenin-PRI complex // inferred from physical interaction /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003779 // actin binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004522 // pancreatic ribonuclease activity // non-traceable author statement /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation /// 0019843 // rRNA binding // traceable author statement /// 0042277 // peptide binding // inferred from direct assay 205142_x_at NM_000033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000033.2 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1), mRNA. /FEA=mRNA /GEN=ABCD1 /PROD=ATP-binding cassette, sub-family D (ALD), member1 /DB_XREF=gi:7262392 /UG=Hs.159546 ATP-binding cassette, sub-family D (ALD), member 1 /FL=gb:NM_000033.2 NM_000033 ATP-binding cassette, sub-family D (ALD), member 1 ABCD1 215 NM_000033 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from direct assay /// 0007031 // peroxisome organization // non-traceable author statement /// 0015910 // peroxisomal long-chain fatty acid import // inferred from genetic interaction /// 0015919 // peroxisomal membrane transport // non-traceable author statement /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042758 // long-chain fatty acid catabolic process // inferred from genetic interaction /// 0042760 // very long-chain fatty acid catabolic process // inferred from direct assay /// 0042760 // very long-chain fatty acid catabolic process // inferred from genetic interaction /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // non-traceable author statement /// 0005325 // peroxisomal fatty-acyl-CoA transporter activity // inferred from genetic interaction /// 0005325 // peroxisomal fatty-acyl-CoA transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 205143_at NM_004386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004386.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan 3 (neurocan) (CSPG3), mRNA. /FEA=mRNA /GEN=CSPG3 /PROD=chondroitin sulfate proteoglycan 3 (neurocan) /DB_XREF=gi:4758083 /UG=Hs.169047 chondroitin sulfate proteoglycan 3 (neurocan) /FL=gb:AF026547.1 gb:NM_004386.1 NM_004386 neurocan NCAN 1463 NM_004386 /// XM_005259745 /// XM_005259746 /// XM_005259747 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 205144_at L03785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L03785.1 /DEF=Human regulatory myosin light chain (MYL5) mRNA, complete cds. /FEA=mRNA /GEN=MYL5 /PROD=myosin regulatory light chain /DB_XREF=gi:189012 /UG=Hs.170482 myosin, light polypeptide 5, regulatory /FL=gb:L03785.1 gb:NM_002477.1 L03785 major facilitator superfamily domain containing 7 MFSD7 84179 NM_001294341 /// NM_001294342 /// NM_032219 /// XM_005272295 /// XM_005272297 /// XM_005272299 /// XM_006713918 /// XM_006713919 /// XR_246613 /// XR_427480 /// XR_427481 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 205145_s_at NM_002477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002477.1 /DEF=Homo sapiens myosin, light polypeptide 5, regulatory (MYL5), mRNA. /FEA=mRNA /GEN=MYL5 /PROD=myosin, light polypeptide 5, regulatory /DB_XREF=gi:4505304 /UG=Hs.170482 myosin, light polypeptide 5, regulatory /FL=gb:L03785.1 gb:NM_002477.1 NM_002477 myosin, light chain 5, regulatory MYL5 4636 NM_002477 /// XM_005272277 /// XM_006713886 /// XM_006713887 0006937 // regulation of muscle contraction // traceable author statement 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205146_x_at NM_004886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004886.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) (APBA3), mRNA. /FEA=mRNA /GEN=APBA3 /PROD=amyloid beta (A4) precursor protein-binding,family A, member 3 (X11-like 2) /DB_XREF=gi:11342677 /UG=Hs.17528 amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) /FL=gb:NM_004886.1 gb:AB021638.1 NM_004886 amyloid beta (A4) precursor protein-binding, family A, member 3 APBA3 9546 NM_004886 /// XM_006722950 /// XM_006722951 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 205147_x_at NM_000631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000631.2 /DEF=Homo sapiens neutrophil cytosolic factor 4 (40kD) (NCF4), transcript variant 1, mRNA. /FEA=mRNA /GEN=NCF4 /PROD=neutrophil cytosolic factor 4 (40kD), isoform 1 /DB_XREF=gi:7382494 /UG=Hs.196352 neutrophil cytosolic factor 4 (40kD) /FL=gb:AB025220.1 gb:NM_000631.2 NM_000631 neutrophil cytosolic factor 4, 40kDa NCF4 4689 NM_000631 /// NM_013416 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from mutant phenotype /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032010 // phagolysosome // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from mutant phenotype /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // traceable author statement 205148_s_at AA071195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA071195 /FEA=EST /DB_XREF=gi:1578556 /DB_XREF=est:zf79c11.s1 /CLONE=IMAGE:383156 /UG=Hs.199250 chloride channel 4 /FL=gb:NM_001830.2 gb:AB019432.1 gb:AF170492.1 AA071195 chloride channel, voltage-sensitive 4 CLCN4 1183 NM_001256944 /// NM_001830 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 205149_s_at NM_001830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001830.2 /DEF=Homo sapiens chloride channel 4 (CLCN4), mRNA. /FEA=mRNA /GEN=CLCN4 /PROD=chloride channel 4 /DB_XREF=gi:11641404 /UG=Hs.199250 chloride channel 4 /FL=gb:NM_001830.2 gb:AB019432.1 gb:AF170492.1 NM_001830 chloride channel, voltage-sensitive 4 CLCN4 1183 NM_001256944 /// NM_001830 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 205150_s_at AV724192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV724192 /FEA=EST /DB_XREF=gi:10828334 /DB_XREF=est:AV724192 /CLONE=HTBAXH10 /UG=Hs.21572 KIAA0644 gene product /FL=gb:AB014544.1 gb:NM_014817.1 AV724192 TLR4 interactor with leucine-rich repeats TRIL 9865 NM_014817 0002376 // immune system process // inferred from electronic annotation /// 0002718 // regulation of cytokine production involved in immune response // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay 205151_s_at NM_014817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014817.1 /DEF=Homo sapiens KIAA0644 gene product (KIAA0644), mRNA. /FEA=mRNA /GEN=KIAA0644 /PROD=KIAA0644 gene product /DB_XREF=gi:7662219 /UG=Hs.21572 KIAA0644 gene product /FL=gb:AB014544.1 gb:NM_014817.1 NM_014817 TLR4 interactor with leucine-rich repeats TRIL 9865 NM_014817 0002376 // immune system process // inferred from electronic annotation /// 0002718 // regulation of cytokine production involved in immune response // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay 205152_at AI003579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI003579 /FEA=EST /DB_XREF=gi:3203913 /DB_XREF=est:ai88d07.s1 /CLONE=IMAGE:1387885 /UG=Hs.22003 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 /FL=gb:NM_003042.1 AI003579 solute carrier family 6 (neurotransmitter transporter), member 1 SLC6A1 6529 NM_003042 /// XM_005265410 /// XM_005265411 /// XM_006713306 0006810 // transport // non-traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014074 // response to purine-containing compound // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051939 // gamma-aminobutyric acid import // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005332 // gamma-aminobutyric acid:sodium symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 205153_s_at NM_001250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001250.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 5 (TNFRSF5), mRNA. /FEA=mRNA /GEN=TNFRSF5 /PROD=CD40 antigen /DB_XREF=gi:4507580 /UG=Hs.25648 tumor necrosis factor receptor superfamily, member 5 /FL=gb:NM_001250.1 NM_001250 CD40 molecule, TNF receptor superfamily member 5 CD40 958 NM_001250 /// NM_152854 /// XM_005260617 /// XM_005260618 /// XM_005260619 /// XM_006723889 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043406 // positive regulation of MAP kinase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 205154_at NM_006338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006338.1 /DEF=Homo sapiens glioma amplified on chromosome 1 protein (leucine-rich) (GAC1), mRNA. /FEA=mRNA /GEN=GAC1 /PROD=glioma amplified on chromosome 1 protein(leucine-rich) /DB_XREF=gi:5453655 /UG=Hs.26312 glioma amplified on chromosome 1 protein (leucine-rich) /FL=gb:AF030435.1 gb:NM_006338.1 NM_006338 leucine rich repeat neuronal 2 LRRN2 10446 NM_006338 /// NM_201630 /// XM_005244827 /// XM_006711115 /// XM_006711116 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 205155_s_at NM_006946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006946.1 /DEF=Homo sapiens spectrin, beta, non-erythrocytic 2 (SPTBN2), mRNA. /FEA=mRNA /GEN=SPTBN2 /PROD=spectrin, beta, non-erythrocytic 2 /DB_XREF=gi:5902121 /UG=Hs.26915 spectrin, beta, non-erythrocytic 2 /FL=gb:AB008567.1 gb:NM_006946.1 NM_006946 spectrin, beta, non-erythrocytic 2 SPTBN2 6712 NM_006946 /// XM_005274192 /// XM_005274193 /// XM_006718669 /// XM_006718670 /// XM_006718671 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021692 // cerebellar Purkinje cell layer morphogenesis // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 205156_s_at NM_020039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020039.1 /DEF=Homo sapiens amiloride-sensitive cation channel 2, neuronal (ACCN2), transcript variant 1, mRNA. /FEA=mRNA /GEN=ACCN2 /PROD=amiloride-sensitive cation channel 2, neuronal,isoform a /DB_XREF=gi:9943845 /UG=Hs.274361 amiloride-sensitive cation channel 2, neuronal /FL=gb:U78180.1 gb:NM_020039.1 NM_020039 acid-sensing (proton-gated) ion channel 1 ASIC1 41 NM_001095 /// NM_001256830 /// NM_020039 /// NR_046389 /// XM_006719397 0001101 // response to acid // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009268 // response to pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0050915 // sensory perception of sour taste // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070207 // protein homotrimerization // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071467 // cellular response to pH // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // traceable author statement /// 0022839 // ion gated channel activity // inferred from electronic annotation /// 0044736 // acid-sensing ion channel activity // inferred from direct assay /// 0044736 // acid-sensing ion channel activity // inferred from sequence or structural similarity 205157_s_at NM_000422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000422.1 /DEF=Homo sapiens keratin 17 (KRT17), mRNA. /FEA=mRNA /GEN=KRT17 /PROD=keratin 17 /DB_XREF=gi:4557700 /UG=Hs.2785 keratin 17 /FL=gb:NM_000422.1 NM_000422 junction plakoglobin /// keratin 17 JUP /// KRT17 3728 /// 3872 NM_000422 /// NM_002230 /// NM_021991 /// XM_005257313 /// XM_005257349 /// XM_006721871 /// XM_006721872 /// XM_006721873 /// XM_006721874 /// XM_006721875 /// XM_006721876 /// XM_006721877 /// XM_006721878 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000902 // cell morphogenesis // not recorded /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from direct assay /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003181 // atrioventricular valve morphogenesis // not recorded /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007369 // gastrulation // not recorded /// 0007398 // ectoderm development // not recorded /// 0007399 // nervous system development // not recorded /// 0008544 // epidermis development // traceable author statement /// 0016331 // morphogenesis of embryonic epithelium // not recorded /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031424 // keratinization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0043588 // skin development // not recorded /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0048599 // oocyte development // not recorded /// 0050982 // detection of mechanical stimulus // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from sequence or structural similarity /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred by curator 0005634 // nucleus // inferred from mutant phenotype /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0005916 // fascia adherens // not recorded /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071665 // gamma-catenin-TCF7L2 complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005198 // structural molecule activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005199 // structural constituent of cell wall // inferred by curator /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032395 // MHC class II receptor activity // inferred from direct assay /// 0042289 // MHC class II protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 205158_at NM_002937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002937.1 /DEF=Homo sapiens ribonuclease, RNase A family, 4 (RNASE4), mRNA. /FEA=mRNA /GEN=RNASE4 /PROD=ribonuclease, RNase A family, 4 /DB_XREF=gi:4506556 /UG=Hs.283749 ribonuclease, RNase A family, 4 /FL=gb:NM_002937.1 gb:D37931.1 NM_002937 ribonuclease, RNase A family, 4 RNASE4 6038 NM_001282192 /// NM_001282193 /// NM_002937 /// NM_194430 /// NM_194431 0001525 // angiogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // traceable author statement /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001556 // oocyte maturation // non-traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // non-traceable author statement /// 0001890 // placenta development // non-traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006379 // mRNA cleavage // non-traceable author statement /// 0006651 // diacylglycerol biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from mutant phenotype /// 0009725 // response to hormone // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032148 // activation of protein kinase B activity // inferred from mutant phenotype /// 0032431 // activation of phospholipase A2 activity // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042592 // homeostatic process // non-traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // non-traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032311 // angiogenin-PRI complex // inferred from physical interaction /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004522 // pancreatic ribonuclease activity // non-traceable author statement /// 0004540 // ribonuclease activity // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation /// 0019843 // rRNA binding // traceable author statement /// 0042277 // peptide binding // inferred from direct assay 205159_at AV756141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV756141 /FEA=EST /DB_XREF=gi:10913989 /DB_XREF=est:AV756141 /CLONE=BMFAKF10 /UG=Hs.285401 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) /FL=gb:NM_000395.1 gb:M59941.1 AV756141 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) CSF2RB 1439 NM_000395 /// XM_005261340 /// XM_005261342 0007165 // signal transduction // non-traceable author statement /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0036016 // cellular response to interleukin-3 // traceable author statement /// 0038043 // interleukin-5-mediated signaling pathway // traceable author statement /// 0038156 // interleukin-3-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030526 // granulocyte macrophage colony-stimulating factor receptor complex // traceable author statement 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004912 // interleukin-3 receptor activity // traceable author statement /// 0004914 // interleukin-5 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205160_at AL360141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL360141.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1635252. /FEA=mRNA /DB_XREF=gi:8919164 /UG=Hs.31034 peroxisomal biogenesis factor 11A /FL=gb:AB015594.1 gb:AF093668.1 gb:NM_003847.1 AL360141 peroxisomal biogenesis factor 11 alpha PEX11A 8800 NM_001271572 /// NM_001271573 /// NM_003847 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044375 // regulation of peroxisome size // inferred from direct assay /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 205161_s_at NM_003847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003847.1 /DEF=Homo sapiens peroxisomal biogenesis factor 11A (PEX11A), mRNA. /FEA=mRNA /GEN=PEX11A /PROD=peroxisomal biogenesis factor 11A /DB_XREF=gi:4505716 /UG=Hs.31034 peroxisomal biogenesis factor 11A /FL=gb:AB015594.1 gb:AF093668.1 gb:NM_003847.1 NM_003847 peroxisomal biogenesis factor 11 alpha PEX11A 8800 NM_001271572 /// NM_001271573 /// NM_003847 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044375 // regulation of peroxisome size // inferred from direct assay /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 205162_at NM_000082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000082.1 /DEF=Homo sapiens Cockayne syndrome 1 (classical) (CKN1), mRNA. /FEA=mRNA /GEN=CKN1 /PROD=Cockayne syndrome 1 protein /DB_XREF=gi:4557466 /UG=Hs.32967 Cockayne syndrome 1 (classical) /FL=gb:NM_000082.1 gb:U28413.1 NM_000082 excision repair cross-complementation group 8 ERCC8 1161 NM_000082 /// NM_001007233 /// NM_001007234 /// NM_001290285 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0009411 // response to UV // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0010165 // response to X-ray // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003678 // DNA helicase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 205163_at NM_013292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013292.1 /DEF=Homo sapiens (clone PWHLC2-24) myosin light chain 2 (HUMMLC2B), mRNA. /FEA=mRNA /GEN=HUMMLC2B /PROD=(clone PWHLC2-24) myosin light chain 2 /DB_XREF=gi:7019426 /UG=Hs.50889 (clone PWHLC2-24) myosin light chain 2 /FL=gb:M21812.1 gb:NM_013292.1 NM_013292 myosin light chain, phosphorylatable, fast skeletal muscle MYLPF 29895 NM_013292 0006955 // immune response // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity 0005765 // lysosomal membrane // inferred from direct assay /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 205164_at NM_014291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014291.1 /DEF=Homo sapiens glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) (GCAT), mRNA. /FEA=mRNA /GEN=GCAT /PROD=glycine C-acetyltransferase(2-amino-3-ketobutyrate coenzyme A ligase) /DB_XREF=gi:7657117 /UG=Hs.54609 glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) /FL=gb:AF077740.1 gb:NM_014291.1 NM_014291 glycine C-acetyltransferase GCAT 23464 NM_001171690 /// NM_014291 /// XM_005261409 /// XM_005261410 /// XM_005261411 /// XM_006724172 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019518 // L-threonine catabolic process to glycine // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008890 // glycine C-acetyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 205165_at NM_001407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001407.1 /DEF=Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog (CELSR3), mRNA. /FEA=mRNA /GEN=CELSR3 /PROD=cadherin EGF LAG seven-pass G-type receptor 3 /DB_XREF=gi:13325065 /UG=Hs.55173 cadherin, EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog /FL=gb:NM_001407.1 gb:AF231023.1 NM_001407 cadherin, EGF LAG seven-pass G-type receptor 3 CELSR3 1951 NM_001407 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // inferred from electronic annotation 205166_at NM_004055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004055.2 /DEF=Homo sapiens calpain 5 (CAPN5), mRNA. /FEA=mRNA /GEN=CAPN5 /PROD=calpain 5 /DB_XREF=gi:6552324 /UG=Hs.6133 calpain 5 /FL=gb:U94346.1 gb:NM_004055.2 NM_004055 calpain 5 CAPN5 726 NM_004055 0006508 // proteolysis // not recorded /// 0007165 // signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205167_s_at NM_001790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001790.2 /DEF=Homo sapiens cell division cycle 25C (CDC25C), transcript variant 1, mRNA. /FEA=mRNA /GEN=CDC25C /PROD=cell division cycle 25C protein, isoform a /DB_XREF=gi:12408659 /UG=Hs.656 cell division cycle 25C /FL=gb:NM_001790.2 gb:M34065.1 NM_001790 cell division cycle 25C CDC25C 995 NM_001287582 /// NM_001287583 /// NM_001790 /// NM_022809 /// XM_005272145 /// XM_005272146 /// XM_006714739 /// XM_006714740 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from genetic interaction /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 205168_at NM_006182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006182.1 /DEF=Homo sapiens discoidin domain receptor family, member 2 (DDR2), mRNA. /FEA=mRNA /GEN=DDR2 /PROD=discoidin domain receptor family, member 2precursor /DB_XREF=gi:5453813 /UG=Hs.71891 discoidin domain receptor family, member 2 /FL=gb:NM_006182.1 NM_006182 discoidin domain receptor tyrosine kinase 2 DDR2 4921 NM_001014796 /// NM_006182 /// XM_005245221 /// XM_006711344 /// XM_006711345 0001503 // ossification // inferred from electronic annotation /// 0003416 // endochondral bone growth // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // traceable author statement /// 0010763 // positive regulation of fibroblast migration // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030500 // regulation of bone mineralization // inferred from mutant phenotype /// 0031214 // biomineral tissue development // inferred from sequence or structural similarity /// 0035988 // chondrocyte proliferation // inferred from sequence or structural similarity /// 0035988 // chondrocyte proliferation // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0090091 // positive regulation of extracellular matrix disassembly // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay 205169_at NM_005057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005057.1 /DEF=Homo sapiens retinoblastoma-binding protein 5 (RBBP5), mRNA. /FEA=mRNA /GEN=RBBP5 /PROD=retinoblastoma-binding protein 5 /DB_XREF=gi:4826969 /UG=Hs.72984 retinoblastoma-binding protein 5 /FL=gb:NM_005057.1 NM_005057 retinoblastoma binding protein 5 RBBP5 5929 NM_001193272 /// NM_001193273 /// NM_005057 /// XM_005245398 /// XM_005245399 /// XM_005245400 /// XM_005245401 /// XM_006711476 /// XM_006711477 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from physical interaction /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 205170_at NM_005419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005419.1 /DEF=Homo sapiens signal transducer and activator of transcription 2, 113kD (STAT2), mRNA. /FEA=mRNA /GEN=STAT2 /PROD=signal transducer and activator of transcription2, 113kD /DB_XREF=gi:4885614 /UG=Hs.72988 signal transducer and activator of transcription 2, 113kD /FL=gb:NM_005419.1 NM_005419 signal transducer and activator of transcription 2, 113kDa STAT2 6773 NM_005419 /// NM_198332 /// XM_005269108 /// XM_005269109 /// XM_005269110 /// XM_005269111 /// XM_006719572 /// XR_245953 /// XR_245954 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 205171_at NM_002830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002830.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (PTPN4), mRNA. /FEA=mRNA /GEN=PTPN4 /PROD=protein tyrosine phosphatase, non-receptor type4 (megakaryocyte) /DB_XREF=gi:4506294 /UG=Hs.73826 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) /FL=gb:M68941.1 gb:NM_002830.1 NM_002830 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) PTPN4 5775 NM_002830 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 205172_x_at NM_007097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007097.1 /DEF=Homo sapiens clathrin, light polypeptide (Lcb) (CLTB), mRNA. /FEA=mRNA /GEN=CLTB /PROD=clathrin, light polypeptide B (Lcb) isoform b /DB_XREF=gi:6005994 /UG=Hs.73919 clathrin, light polypeptide (Lcb) /FL=gb:M20469.1 gb:NM_007097.1 NM_007097 clathrin, light chain B CLTB 1212 NM_001834 /// NM_007097 /// NR_045724 /// XM_006714818 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 205173_x_at NM_001779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001779.1 /DEF=Homo sapiens CD58 antigen, (lymphocyte function-associated antigen 3) (CD58), mRNA. /FEA=mRNA /GEN=CD58 /PROD=CD58 antigen, (lymphocyte function-associatedantigen 3) /DB_XREF=gi:4502676 /UG=Hs.75626 CD58 antigen, (lymphocyte function-associated antigen 3) /FL=gb:NM_001779.1 NM_001779 CD58 molecule CD58 965 NM_001144822 /// NM_001779 /// NR_026665 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 205174_s_at NM_012413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012413.2 /DEF=Homo sapiens glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (QPCT), mRNA. /FEA=mRNA /GEN=QPCT /PROD=glutaminyl-peptide cyclotransferase precursor /DB_XREF=gi:9257235 /UG=Hs.79033 glutaminyl-peptide cyclotransferase (glutaminyl cyclase) /FL=gb:NM_012413.2 NM_012413 glutaminyl-peptide cyclotransferase QPCT 25797 NM_012413 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0017186 // peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016603 // glutaminyl-peptide cyclotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205175_s_at NM_000221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000221.1 /DEF=Homo sapiens ketohexokinase (fructokinase) (KHK), transcript variant a, mRNA. /FEA=mRNA /GEN=KHK /PROD=ketohexokinase, isoform a /DB_XREF=gi:4557692 /UG=Hs.81454 ketohexokinase (fructokinase) /FL=gb:NM_000221.1 NM_000221 ketohexokinase (fructokinase) KHK 3795 NM_000221 /// NM_006488 /// XM_005264294 /// XM_005264296 /// XM_005264298 /// XM_006712008 /// XM_006712009 /// XM_006712010 /// XM_006712011 /// XM_006712012 /// XM_006712013 /// XM_006712014 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006001 // fructose catabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004454 // ketohexokinase activity // not recorded /// 0004454 // ketohexokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205176_s_at NM_014288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014288.1 /DEF=Homo sapiens integrin beta 3 binding protein (beta3-endonexin) (ITGB3BP), mRNA. /FEA=mRNA /GEN=ITGB3BP /PROD=integrin beta 3 binding protein(beta3-endonexin) /DB_XREF=gi:7657205 /UG=Hs.82084 integrin beta 3 binding protein (beta3-endonexin) /FL=gb:BC005301.1 gb:AF175306.1 gb:NM_014288.1 NM_014288 integrin beta 3 binding protein (beta3-endonexin) ITGB3BP 23421 NM_001206739 /// NM_014288 /// NR_045147 /// XM_006710514 /// XM_006710515 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement 0004871 // signal transducer activity // traceable author statement /// 0008022 // protein C-terminus binding // traceable author statement 205177_at NM_003281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003281.1 /DEF=Homo sapiens troponin I, skeletal, slow (TNNI1), mRNA. /FEA=mRNA /GEN=TNNI1 /PROD=troponin I, skeletal, slow /DB_XREF=gi:4507618 /UG=Hs.84673 troponin I, skeletal, slow /FL=gb:J04760.1 gb:NM_003281.1 NM_003281 troponin I type 1 (skeletal, slow) TNNI1 7135 NM_003281 0006942 // regulation of striated muscle contraction // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205178_s_at NM_006910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006910.1 /DEF=Homo sapiens retinoblastoma-binding protein 6 (RBBP6), mRNA. /FEA=mRNA /GEN=RBBP6 /PROD=retinoblastoma-binding protein 6 /DB_XREF=gi:5902043 /UG=Hs.85273 retinoblastoma-binding protein 6 /FL=gb:NM_006910.1 NM_006910 retinoblastoma binding protein 6 RBBP6 5930 NM_006910 /// NM_018703 /// NM_032626 /// XM_005255461 /// XM_005255462 0001701 // in utero embryonic development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0061053 // somite development // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205179_s_at AI814527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814527 /FEA=EST /DB_XREF=gi:5425742 /DB_XREF=est:wj74c02.x1 /CLONE=IMAGE:2408546 /UG=Hs.86947 a disintegrin and metalloproteinase domain 8 /FL=gb:D26579.1 gb:NM_001109.1 AI814527 ADAM metallopeptidase domain 8 ADAM8 101 NM_001109 /// NM_001164489 /// NM_001164490 /// XM_005252655 /// XM_005252656 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002523 // leukocyte migration involved in inflammatory response // inferred from sequence or structural similarity /// 0002675 // positive regulation of acute inflammatory response // inferred from sequence or structural similarity /// 0002693 // positive regulation of cellular extravasation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0010954 // positive regulation of protein processing // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035419 // activation of MAPK activity involved in innate immune response // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048247 // lymphocyte chemotaxis // inferred from sequence or structural similarity /// 0050714 // positive regulation of protein secretion // inferred by curator /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 2000309 // positive regulation of tumor necrosis factor (ligand) superfamily member 11 production // inferred from sequence or structural similarity /// 2000391 // positive regulation of neutrophil extravasation // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from electronic annotation /// 2000415 // positive regulation of fibronectin-dependent thymocyte migration // inferred from sequence or structural similarity /// 2000418 // positive regulation of eosinophil migration // inferred from sequence or structural similarity 0002102 // podosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032010 // phagolysosome // inferred from direct assay /// 0032127 // dense core granule membrane // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070820 // tertiary granule // inferred from direct assay /// 0071065 // alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex // inferred from direct assay /// 0071133 // alpha9-beta1 integrin-ADAM8 complex // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 205180_s_at NM_001109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001109.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8), mRNA. /FEA=mRNA /GEN=ADAM8 /PROD=a disintegrin and metalloproteinase domain 8precursor /DB_XREF=gi:4557252 /UG=Hs.86947 a disintegrin and metalloproteinase domain 8 /FL=gb:D26579.1 gb:NM_001109.1 NM_001109 ADAM metallopeptidase domain 8 ADAM8 101 NM_001109 /// NM_001164489 /// NM_001164490 /// XM_005252655 /// XM_005252656 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002523 // leukocyte migration involved in inflammatory response // inferred from sequence or structural similarity /// 0002675 // positive regulation of acute inflammatory response // inferred from sequence or structural similarity /// 0002693 // positive regulation of cellular extravasation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0010954 // positive regulation of protein processing // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035419 // activation of MAPK activity involved in innate immune response // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048247 // lymphocyte chemotaxis // inferred from sequence or structural similarity /// 0050714 // positive regulation of protein secretion // inferred by curator /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 2000309 // positive regulation of tumor necrosis factor (ligand) superfamily member 11 production // inferred from sequence or structural similarity /// 2000391 // positive regulation of neutrophil extravasation // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from electronic annotation /// 2000415 // positive regulation of fibronectin-dependent thymocyte migration // inferred from sequence or structural similarity /// 2000418 // positive regulation of eosinophil migration // inferred from sequence or structural similarity 0002102 // podosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032010 // phagolysosome // inferred from direct assay /// 0032127 // dense core granule membrane // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070820 // tertiary granule // inferred from direct assay /// 0071065 // alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex // inferred from direct assay /// 0071133 // alpha9-beta1 integrin-ADAM8 complex // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 205181_at NM_006299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006299.1 /DEF=Homo sapiens zinc finger protein 193 (ZNF193), mRNA. /FEA=mRNA /GEN=ZNF193 /PROD=zinc finger protein 193 /DB_XREF=gi:5454179 /UG=Hs.96448 zinc finger protein 193 /FL=gb:U62392.1 gb:NM_006299.1 NM_006299 zinc finger and SCAN domain containing 9 ZSCAN9 7746 NM_001199479 /// NM_001199480 /// NM_006299 /// XM_006715182 /// XM_006715183 /// XM_006715184 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205182_s_at NM_014347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014347.1 /DEF=Homo sapiens zinc finger protein (ZF5128), mRNA. /FEA=mRNA /GEN=ZF5128 /PROD=zinc finger protein /DB_XREF=gi:7657692 /UG=Hs.296365 zinc finger protein /FL=gb:AF060503.1 gb:NM_014347.1 NM_014347 zinc finger protein 324 ZNF324 25799 NM_014347 /// XM_005258713 /// XM_006723129 /// XM_006723130 /// XM_006723131 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205183_at NM_002138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002138.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) (HNRPD), mRNA. /FEA=mRNA /GEN=HNRPD /PROD=heterogeneous nuclear ribonucleoprotein D(AU-rich element RNA-binding protein 1, 37kD) /DB_XREF=gi:4504448 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:U02019.1 gb:NM_002138.1 NM_002138 0006402 // mRNA catabolic process // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003729 // mRNA binding // non-traceable author statement 205184_at NM_004485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004485.1 /DEF=Homo sapiens guanine nucleotide binding protein 4 (GNG4), mRNA. /FEA=mRNA /GEN=GNG4 /PROD=guanine nucleotide binding protein 4 /DB_XREF=gi:4758449 /UG=Hs.32976 guanine nucleotide binding protein 4 /FL=gb:NM_004485.1 gb:U31382.1 NM_004485 guanine nucleotide binding protein (G protein), gamma 4 GNG4 2786 NM_001098721 /// NM_001098722 /// NM_004485 /// XM_006711761 /// XM_006711762 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205185_at NM_006846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006846.1 /DEF=Homo sapiens serine protease inhibitor, Kazal type, 5 (SPINK5), mRNA. /FEA=mRNA /GEN=SPINK5 /PROD=serine protease inhibitor, Kazal type, 5 /DB_XREF=gi:5803218 /UG=Hs.331555 serine protease inhibitor, Kazal type, 5 /FL=gb:NM_006846.1 NM_006846 serine peptidase inhibitor, Kazal type 5 SPINK5 11005 NM_001127698 /// NM_001127699 /// NM_006846 0006508 // proteolysis // inferred from electronic annotation /// 0009913 // epidermal cell differentiation // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030855 // epithelial cell differentiation // traceable author statement /// 0035315 // hair cell differentiation // traceable author statement /// 0042640 // anagen // traceable author statement /// 0045580 // regulation of T cell differentiation // traceable author statement /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097209 // epidermal lamellar body // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205186_at NM_003462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003462.2 /DEF=Homo sapiens dynein, axonemal, light intermediate polypeptide (P28), mRNA. /FEA=mRNA /GEN=P28 /PROD=axonemal dynein light chain /DB_XREF=gi:13518030 /UG=Hs.33846 dynein, axonemal, light intermediate polypeptide /FL=gb:NM_003462.2 gb:AF006386.1 NM_003462 dynein, axonemal, light intermediate chain 1 DNALI1 7802 NM_003462 /// XM_005271172 0006928 // cellular component movement // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005858 // axonemal dynein complex // traceable author statement /// 0005930 // axoneme // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205187_at AF010601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010601.1 /DEF=Homo sapiens SMAD5 (Smad5) mRNA, complete cds. /FEA=mRNA /GEN=Smad5 /PROD=SMAD5 /DB_XREF=gi:2317785 /UG=Hs.37501 MAD (mothers against decapentaplegic, Drosophila) homolog 5 /FL=gb:U59913.1 gb:U73825.1 gb:AF009678.1 gb:AF010601.1 gb:NM_005903.1 AF010601 SMAD family member 5 SMAD5 4090 NM_001001419 /// NM_001001420 /// NM_005903 0001503 // ossification // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205188_s_at NM_005903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005903.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 5 (MADH5), mRNA. /FEA=mRNA /GEN=MADH5 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 5 /DB_XREF=gi:5174514 /UG=Hs.37501 MAD (mothers against decapentaplegic, Drosophila) homolog 5 /FL=gb:U59913.1 gb:U73825.1 gb:AF009678.1 gb:AF010601.1 gb:NM_005903.1 NM_005903 SMAD family member 5 SMAD5 4090 NM_001001419 /// NM_001001420 /// NM_005903 0001503 // ossification // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205189_s_at NM_000136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000136.1 /DEF=Homo sapiens Fanconi anemia, complementation group C (FANCC), mRNA. /FEA=mRNA /GEN=FANCC /PROD=Fanconi anemia, complementation group C /DB_XREF=gi:4557588 /UG=Hs.37953 Fanconi anemia, complementation group C /FL=gb:NM_000136.1 NM_000136 Fanconi anemia, complementation group C FANCC 2176 NM_000136 /// NM_001243743 /// NM_001243744 /// XM_005251802 /// XM_006717001 /// XM_006717002 /// XM_006717003 /// XM_006717004 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205190_at NM_002670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002670.1 /DEF=Homo sapiens plastin 1 (I isoform) (PLS1), mRNA. /FEA=mRNA /GEN=PLS1 /PROD=plastin 1 /DB_XREF=gi:4505896 /UG=Hs.430 plastin 1 (I isoform) /FL=gb:L20826.1 gb:NM_002670.1 NM_002670 plastin 1 PLS1 5357 NM_001145319 /// NM_001172312 /// NM_002670 /// XM_006713660 /// XM_006713661 /// XM_006713662 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 205191_at NM_006915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006915.1 /DEF=Homo sapiens retinitis pigmentosa 2 (X-linked recessive) (RP2), mRNA. /FEA=mRNA /GEN=RP2 /PROD=XRP2 protein /DB_XREF=gi:5902059 /UG=Hs.44766 retinitis pigmentosa 2 (X-linked recessive) /FL=gb:NM_006915.1 NM_006915 retinitis pigmentosa 2 (X-linked recessive) RP2 6102 NM_006915 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from genetic interaction /// 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from genetic interaction /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 205192_at NM_003954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003954.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 14 (MAP3K14), mRNA. /FEA=mRNA /GEN=MAP3K14 /PROD=mitogen-activated protein kinase kinase kinase14 /DB_XREF=gi:4505396 /UG=Hs.47007 mitogen-activated protein kinase kinase kinase 14 /FL=gb:NM_003954.1 NM_003954 mitogen-activated protein kinase kinase kinase 14 MAP3K14 9020 NM_003954 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from sequence or structural similarity /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205193_at NM_012323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012323.1 /DEF=Homo sapiens v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein F (MAFF), mRNA. /FEA=mRNA /GEN=MAFF /PROD=v-maf musculoaponeurotic fibrosarcoma (avian)oncogene family, protein F /DB_XREF=gi:6912489 /UG=Hs.51305 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein F /FL=gb:AB025247.1 gb:NM_012323.1 NM_012323 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F MAFF 23764 NM_001161572 /// NM_001161573 /// NM_001161574 /// NM_012323 /// NM_152878 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007567 // parturition // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045604 // regulation of epidermal cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205194_at NM_004577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004577.1 /DEF=Homo sapiens phosphoserine phosphatase (PSPH), mRNA. /FEA=mRNA /GEN=PSPH /PROD=phosphoserine phosphatase /DB_XREF=gi:4758971 /UG=Hs.56407 phosphoserine phosphatase /FL=gb:NM_004577.1 NM_004577 phosphoserine phosphatase PSPH 5723 NM_004577 /// XM_005271773 /// XM_005271774 /// XM_005271775 /// XM_005271776 /// XM_005271777 /// XM_006715760 /// XM_006715761 0006563 // L-serine metabolic process // inferred from direct assay /// 0006564 // L-serine biosynthetic process // not recorded /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0004647 // phosphoserine phosphatase activity // inferred from direct assay /// 0004647 // phosphoserine phosphatase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205195_at NM_001283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001283.1 /DEF=Homo sapiens adaptor-related protein complex 1, sigma 1 subunit (AP1S1), mRNA. /FEA=mRNA /GEN=AP1S1 /PROD=adaptor-related protein complex 1, sigma 1subunit /DB_XREF=gi:4557470 /UG=Hs.57600 adaptor-related protein complex 1, sigma 1 subunit /FL=gb:AB015319.1 gb:NM_001283.1 NM_001283 adaptor-related protein complex 1, sigma 1 subunit AP1S1 1174 NM_001283 /// NM_057089 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 205196_s_at NM_001283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001283.1 /DEF=Homo sapiens adaptor-related protein complex 1, sigma 1 subunit (AP1S1), mRNA. /FEA=mRNA /GEN=AP1S1 /PROD=adaptor-related protein complex 1, sigma 1subunit /DB_XREF=gi:4557470 /UG=Hs.57600 adaptor-related protein complex 1, sigma 1 subunit /FL=gb:AB015319.1 gb:NM_001283.1 NM_001283 adaptor-related protein complex 1, sigma 1 subunit AP1S1 1174 NM_001283 /// NM_057089 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 205197_s_at BE567813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE567813 /FEA=EST /DB_XREF=gi:9811533 /DB_XREF=est:601340481F1 /CLONE=IMAGE:3682485 /UG=Hs.606 ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) /FL=gb:L06133.1 gb:NM_000052.1 BE567813 ATPase, Cu++ transporting, alpha polypeptide ATP7A 538 NM_000052 /// NM_001282224 /// NR_104109 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002082 // regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 0006568 // tryptophan metabolic process // inferred from sequence or structural similarity /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006584 // catecholamine metabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from mutant phenotype /// 0006878 // cellular copper ion homeostasis // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010041 // response to iron(III) ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010273 // detoxification of copper ion // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015677 // copper ion import // inferred from sequence or structural similarity /// 0018205 // peptidyl-lysine modification // inferred from sequence or structural similarity /// 0019430 // removal of superoxide radicals // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0030001 // metal ion transport // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0042093 // T-helper cell differentiation // inferred from sequence or structural similarity /// 0042414 // epinephrine metabolic process // inferred from sequence or structural similarity /// 0042415 // norepinephrine metabolic process // inferred from sequence or structural similarity /// 0042417 // dopamine metabolic process // inferred from sequence or structural similarity /// 0042421 // norepinephrine biosynthetic process // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from sequence or structural similarity /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043588 // skin development // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048553 // negative regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0051353 // positive regulation of oxidoreductase activity // inferred from direct assay /// 0051542 // elastin biosynthetic process // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060003 // copper ion export // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004008 // copper-exporting ATPase activity // inferred from sequence or structural similarity /// 0005375 // copper ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0016532 // superoxide dismutase copper chaperone activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0032767 // copper-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205198_s_at NM_000052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000052.1 /DEF=Homo sapiens ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) (ATP7A), mRNA. /FEA=mRNA /GEN=ATP7A /PROD=ATPase, Cu++ transporting, alpha polypeptide /DB_XREF=gi:4502320 /UG=Hs.606 ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) /FL=gb:L06133.1 gb:NM_000052.1 NM_000052 ATPase, Cu++ transporting, alpha polypeptide ATP7A 538 NM_000052 /// NM_001282224 /// NR_104109 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002082 // regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 0006568 // tryptophan metabolic process // inferred from sequence or structural similarity /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006584 // catecholamine metabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from mutant phenotype /// 0006878 // cellular copper ion homeostasis // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010041 // response to iron(III) ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010273 // detoxification of copper ion // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015677 // copper ion import // inferred from sequence or structural similarity /// 0018205 // peptidyl-lysine modification // inferred from sequence or structural similarity /// 0019430 // removal of superoxide radicals // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0030001 // metal ion transport // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0042093 // T-helper cell differentiation // inferred from sequence or structural similarity /// 0042414 // epinephrine metabolic process // inferred from sequence or structural similarity /// 0042415 // norepinephrine metabolic process // inferred from sequence or structural similarity /// 0042417 // dopamine metabolic process // inferred from sequence or structural similarity /// 0042421 // norepinephrine biosynthetic process // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from sequence or structural similarity /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043588 // skin development // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048553 // negative regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0051353 // positive regulation of oxidoreductase activity // inferred from direct assay /// 0051542 // elastin biosynthetic process // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060003 // copper ion export // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004008 // copper-exporting ATPase activity // inferred from sequence or structural similarity /// 0005375 // copper ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0016532 // superoxide dismutase copper chaperone activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0032767 // copper-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205199_at NM_001216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001216.1 /DEF=Homo sapiens carbonic anhydrase IX (CA9), mRNA. /FEA=mRNA /GEN=CA9 /PROD=carbonic anhydrase IX precursor /DB_XREF=gi:9955947 /UG=Hs.63287 carbonic anhydrase IX /FL=gb:NM_001216.1 NM_001216 carbonic anhydrase IX CA9 768 NM_001216 /// XM_006716866 /// XM_006716867 /// XM_006716868 /// XM_006716869 /// XM_006716870 /// XR_428428 /// XR_428429 0001666 // response to hypoxia // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046903 // secretion // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205200_at NM_003278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003278.1 /DEF=Homo sapiens tetranectin (plasminogen-binding protein) (TNA), mRNA. /FEA=mRNA /GEN=TNA /PROD=tetranectin (plasminogen-binding protein) /DB_XREF=gi:4507556 /UG=Hs.65424 tetranectin (plasminogen-binding protein) /FL=gb:NM_003278.1 NM_003278 C-type lectin domain family 3, member B /// exosome component 7 CLEC3B /// EXOSC7 7123 /// 23016 NM_003278 /// NM_015004 /// NR_023353 /// XM_005265426 /// XM_006713035 /// XR_245104 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from expression pattern /// 0006364 // rRNA processing // traceable author statement /// 0006401 // RNA catabolic process // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010756 // positive regulation of plasminogen activation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030282 // bone mineralization // inferred from direct assay /// 0030282 // bone mineralization // inferred from expression pattern /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071310 // cellular response to organic substance // inferred from expression pattern /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // traceable author statement /// 0001652 // granular component // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0036143 // kringle domain binding // inferred from physical interaction 205201_at NM_000168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000168.2 /DEF=Homo sapiens GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) (GLI3), mRNA. /FEA=mRNA /GEN=GLI3 /PROD=GLI-Kruppel family member GLI3 /DB_XREF=gi:13518031 /UG=Hs.72916 GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) /FL=gb:NM_000168.2 gb:M57609.1 NM_000168 GLI family zinc finger 3 GLI3 2737 NM_000168 /// XM_005249703 /// XM_005249704 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007442 // hindgut morphogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0021513 // spinal cord dorsal/ventral patterning // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021543 // pallium development // inferred from electronic annotation /// 0021544 // subpallium development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021775 // smoothened signaling pathway involved in ventral spinal cord interneuron specification // inferred from electronic annotation /// 0021776 // smoothened signaling pathway involved in spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021798 // forebrain dorsal/ventral pattern formation // inferred from electronic annotation /// 0021801 // cerebral cortex radial glia guided migration // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022018 // lateral ganglionic eminence cell proliferation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0035295 // tube development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043585 // nose morphogenesis // traceable author statement /// 0043586 // tongue development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from sequence or structural similarity /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0046639 // negative regulation of alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060366 // lambdoid suture morphogenesis // inferred from electronic annotation /// 0060367 // sagittal suture morphogenesis // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0060840 // artery development // inferred from electronic annotation /// 0060873 // anterior semicircular canal development // inferred from electronic annotation /// 0060875 // lateral semicircular canal development // inferred from electronic annotation /// 0061005 // cell differentiation involved in kidney development // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005929 // cilium // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0072372 // primary cilium // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205202_at NM_005389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005389.1 /DEF=Homo sapiens protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), mRNA. /FEA=mRNA /GEN=PCMT1 /PROD=protein-L-isoaspartate (D-aspartate)O-methyltransferase /DB_XREF=gi:4885538 /UG=Hs.79137 protein-L-isoaspartate (D-aspartate) O-methyltransferase /FL=gb:D25545.1 gb:NM_005389.1 NM_005389 protein-L-isoaspartate (D-aspartate) O-methyltransferase PCMT1 5110 NM_001252049 /// NM_001252050 /// NM_001252051 /// NM_001252052 /// NM_001252053 /// NM_005389 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006479 // protein methylation // traceable author statement /// 0030091 // protein repair // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205203_at NM_002662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002662.1 /DEF=Homo sapiens phospholipase D1, phophatidylcholine-specific (PLD1), mRNA. /FEA=mRNA /GEN=PLD1 /PROD=phospholipase D1, phophatidylcholine-specific /DB_XREF=gi:4505872 /UG=Hs.82587 phospholipase D1, phophatidylcholine-specific /FL=gb:U38545.1 gb:NM_002662.1 NM_002662 phospholipase D1, phosphatidylcholine-specific PLD1 5337 NM_001130081 /// NM_002662 /// XM_005247533 /// XM_005247534 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 205204_at NM_021077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021077.1 /DEF=Homo sapiens neuromedin B (NMB), mRNA. /FEA=mRNA /GEN=NMB /PROD=neuromedin B /DB_XREF=gi:10835106 /UG=Hs.83321 neuromedin B /FL=gb:NM_021077.1 gb:M21551.1 NM_021077 neuromedin B NMB 4828 NM_021077 /// NM_205858 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008343 // adult feeding behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0050482 // arachidonic acid secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0031710 // neuromedin B receptor binding // inferred from electronic annotation 205205_at NM_006509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006509.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) (RELB), mRNA. /FEA=mRNA /GEN=RELB /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog B (nuclear factor of kappa light polypeptide geneenhancer in B-cells 3) /DB_XREF=gi:5730006 /UG=Hs.858 v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) /FL=gb:M83221.1 gb:NM_006509.1 NM_006509 v-rel avian reticuloendotheliosis viral oncogene homolog B RELB 5971 NM_006509 /// XM_005259127 /// XM_005259128 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0045063 // T-helper 1 cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205206_at NM_000216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000216.1 /DEF=Homo sapiens Kallmann syndrome 1 sequence (KAL1), mRNA. /FEA=mRNA /GEN=KAL1 /PROD=Kallmann syndrome 1 protein /DB_XREF=gi:4557682 /UG=Hs.89591 Kallmann syndrome 1 sequence /FL=gb:M97252.1 gb:NM_000216.1 NM_000216 Kallmann syndrome 1 sequence KAL1 3730 NM_000216 /// XM_005274501 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205207_at NM_000600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000600.1 /DEF=Homo sapiens interleukin 6 (interferon, beta 2) (IL6), mRNA. /FEA=mRNA /GEN=IL6 /PROD=interleukin 6 (interferon, beta 2) /DB_XREF=gi:10834983 /UG=Hs.93913 interleukin 6 (interferon, beta 2) /FL=gb:NM_000600.1 gb:M14584.1 gb:M18403.1 gb:M29150.1 gb:M54894.1 NM_000600 interleukin 6 IL6 3569 NM_000600 /// XM_005249745 0001781 // neutrophil apoptotic process // inferred from direct assay /// 0002384 // hepatic immune response // inferred from direct assay /// 0002384 // hepatic immune response // traceable author statement /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002675 // positive regulation of acute inflammatory response // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006953 // acute-phase response // traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // inferred by curator /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010574 // regulation of vascular endothelial growth factor production // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010888 // negative regulation of lipid storage // non-traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from expression pattern /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from mutant phenotype /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0032966 // negative regulation of collagen biosynthetic process // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045079 // negative regulation of chemokine biosynthetic process // inferred from sequence or structural similarity /// 0045188 // regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // non-traceable author statement /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // traceable author statement /// 0045721 // negative regulation of gluconeogenesis // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046849 // bone remodeling // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048635 // negative regulation of muscle organ development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from expression pattern /// 0050830 // defense response to Gram-positive bacterium // inferred from expression pattern /// 0050871 // positive regulation of B cell activation // inferred from direct assay /// 0051024 // positive regulation of immunoglobulin secretion // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070091 // glucagon secretion // inferred from sequence or structural similarity /// 0070102 // interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0072540 // T-helper 17 cell lineage commitment // inferred from sequence or structural similarity /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 2000366 // positive regulation of STAT protein import into nucleus // inferred by curator /// 2000676 // positive regulation of type B pancreatic cell apoptotic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // non-traceable author statement /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 205208_at NM_012190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012190.1 /DEF=Homo sapiens formyltetrahydrofolate dehydrogenase (FTHFD), mRNA. /FEA=mRNA /GEN=FTHFD /PROD=formyltetrahydrofolate dehydrogenase /DB_XREF=gi:7110594 /UG=Hs.9520 formyltetrahydrofolate dehydrogenase /FL=gb:AF052732.1 gb:NM_012190.1 NM_012190 aldehyde dehydrogenase 1 family, member L1 ALDH1L1 10840 NM_001270364 /// NM_001270365 /// NM_012190 /// NR_072979 /// XM_006713481 /// XM_006713482 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009258 // 10-formyltetrahydrofolate catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016155 // formyltetrahydrofolate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation 205209_at BC000254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000254.1 /DEF=Homo sapiens, activin A receptor, type IB, clone MGC:2177, mRNA, complete cds. /FEA=mRNA /PROD=activin A receptor, type IB /DB_XREF=gi:12652986 /UG=Hs.99954 activin A receptor, type IB /FL=gb:NM_004302.2 gb:BC000254.1 gb:Z22536.1 gb:U14722.1 BC000254 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 205210_at NM_004257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004257.1 /DEF=Homo sapiens TGF beta receptor associated protein -1 (TRAP-1), mRNA. /FEA=mRNA /GEN=TRAP-1 /PROD=TGF beta receptor associated protein -1 /DB_XREF=gi:4759259 /UG=Hs.101766 TGF beta receptor associated protein -1 /FL=gb:AF022795.1 gb:NM_004257.1 NM_004257 transforming growth factor, beta receptor associated protein 1 TGFBRAP1 9392 NM_001142621 /// NM_004257 /// XM_006712860 /// XM_006712861 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay 205211_s_at NM_004292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004292.1 /DEF=Homo sapiens ras inhibitor (RIN1), mRNA. /FEA=mRNA /GEN=RIN1 /PROD=ras inhibitor /DB_XREF=gi:4759039 /UG=Hs.1030 ras inhibitor /FL=gb:L36463.1 gb:NM_004292.1 NM_004292 Ras and Rab interactor 1 RIN1 9610 NM_004292 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205212_s_at NM_014716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014716.1 /DEF=Homo sapiens KIAA0050 gene product (ACAP1), mRNA. /FEA=mRNA /GEN=ACAP1 /PROD=centaurin beta1 /DB_XREF=gi:7661879 /UG=Hs.108947 KIAA0050 gene product /FL=gb:D30758.1 gb:NM_014716.1 NM_014716 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 ACAP1 9744 NM_014716 /// XM_005256878 /// XR_243574 /// XR_429827 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205213_at NM_014716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014716.1 /DEF=Homo sapiens KIAA0050 gene product (ACAP1), mRNA. /FEA=mRNA /GEN=ACAP1 /PROD=centaurin beta1 /DB_XREF=gi:7661879 /UG=Hs.108947 KIAA0050 gene product /FL=gb:D30758.1 gb:NM_014716.1 NM_014716 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 ACAP1 9744 NM_014716 /// XM_005256878 /// XR_243574 /// XR_429827 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205214_at NM_004226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004226.1 /DEF=Homo sapiens serinethreonine kinase 17b (apoptosis-inducing) (STK17B), mRNA. /FEA=mRNA /GEN=STK17B /PROD=serinethreonine kinase 17b(apoptosis-inducing) /DB_XREF=gi:4758193 /UG=Hs.120996 serinethreonine kinase 17b (apoptosis-inducing) /FL=gb:AB011421.1 gb:NM_004226.1 NM_004226 serine/threonine kinase 17b STK17B 9262 NM_004226 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205215_at NM_007212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007212.1 /DEF=Homo sapiens ring finger protein 2 (RNF2), mRNA. /FEA=mRNA /GEN=RNF2 /PROD=ring finger protein 2 /DB_XREF=gi:6005746 /UG=Hs.124186 ring finger protein 2 /FL=gb:AF141327.1 gb:NM_007212.1 NM_007212 ring finger protein 2 RNF2 6045 NM_007212 /// XM_005245413 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0036353 // histone H2A-K119 monoubiquitination // inferred from sequence or structural similarity 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 205216_s_at NM_000042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000042.1 /DEF=Homo sapiens apolipoprotein H (beta-2-glycoprotein I) (APOH), mRNA. /FEA=mRNA /GEN=APOH /PROD=beta-2-glycoprotein I precursor /DB_XREF=gi:4557326 /UG=Hs.1252 apolipoprotein H (beta-2-glycoprotein I) /FL=gb:M62839.1 gb:NM_000042.1 NM_000042 apolipoprotein H (beta-2-glycoprotein I) APOH 350 NM_000042 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0007597 // blood coagulation, intrinsic pathway // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // traceable author statement /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0031639 // plasminogen activation // inferred from direct assay /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from direct assay /// 0034197 // triglyceride transport // inferred from sequence or structural similarity /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from direct assay /// 0051917 // regulation of fibrinolysis // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0060230 // lipoprotein lipase activator activity // inferred from direct assay 205217_at NM_004085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004085.2 /DEF=Homo sapiens translocase of inner mitochondrial membrane 8 (yeast) homolog A (TIMM8A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=TIMM8A /PROD=translocase of inner mitochondrial membrane 8(yeast) homolog A /DB_XREF=gi:6138974 /UG=Hs.125565 translocase of inner mitochondrial membrane 8 (yeast) homolog A /FL=gb:U66035.1 gb:NM_004085.2 NM_004085 translocase of inner mitochondrial membrane 8 homolog A (yeast) TIMM8A 1678 NM_001145951 /// NM_004085 /// NM_032696 /// XM_005262092 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072321 // chaperone-mediated protein transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 205218_at NM_006466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006466.1 /DEF=Homo sapiens polymerase (RNA) III (DNA directed) (39kD) (RPC39), mRNA. /FEA=mRNA /GEN=RPC39 /PROD=polymerase (RNA) III (DNA directed) (39kD) /DB_XREF=gi:5454019 /UG=Hs.128207 polymerase (RNA) III (DNA directed) (39kD) /FL=gb:U93869.1 gb:NM_006466.1 NM_006466 polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa POLR3F 10621 NM_001282526 /// NM_006466 /// NR_104209 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // non-traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205219_s_at NM_002044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002044.1 /DEF=Homo sapiens galactokinase 2 (GALK2), mRNA. /FEA=mRNA /GEN=GALK2 /PROD=galactokinase 2 /DB_XREF=gi:4503896 /UG=Hs.129228 galactokinase 2 /FL=gb:BC005141.1 gb:M84443.1 gb:NM_002044.1 NM_002044 galactokinase 2 GALK2 2585 NM_001001556 /// NM_001289030 /// NM_001289031 /// NM_002044 /// XM_005254279 /// XM_005254280 /// XM_005254284 /// XM_006720461 /// XM_006720462 /// XM_006720463 /// XM_006720464 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004335 // galactokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0033858 // N-acetylgalactosamine kinase activity // inferred from electronic annotation 205220_at NM_006018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006018.1 /DEF=Homo sapiens putative chemokine receptor; GTP-binding protein (HM74), mRNA. /FEA=mRNA /GEN=HM74 /PROD=putative chemokine receptor; GTP-bindingprotein /DB_XREF=gi:5174460 /UG=Hs.137555 putative chemokine receptor; GTP-binding protein /FL=gb:NM_006018.1 NM_006018 hydroxycarboxylic acid receptor 3 HCAR3 8843 NM_006018 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 205221_at NM_000187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000187.1 /DEF=Homo sapiens homogentisate 1,2-dioxygenase (homogentisate oxidase) (HGD), mRNA. /FEA=mRNA /GEN=HGD /PROD=homogentisate 1,2-dioxygenase /DB_XREF=gi:4504380 /UG=Hs.15113 homogentisate 1,2-dioxygenase (homogentisate oxidase) /FL=gb:U63008.1 gb:AF045167.1 gb:NM_000187.1 NM_000187 homogentisate 1,2-dioxygenase HGD 3081 NM_000187 /// XM_005247412 /// XM_005247413 /// XM_005247414 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004411 // homogentisate 1,2-dioxygenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205222_at NM_001966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001966.1 /DEF=Homo sapiens enoyl-Coenzyme A, hydratase3-hydroxyacyl Coenzyme A dehydrogenase (EHHADH), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=EHHADH /PROD=enoyl-Coenzyme A, hydratase3-hydroxyacylCoenzyme A dehydrogenase /DB_XREF=gi:4503496 /UG=Hs.1531 enoyl-Coenzyme A, hydratase3-hydroxyacyl Coenzyme A dehydrogenase /FL=gb:NM_001966.1 gb:L07077.1 NM_001966 enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase EHHADH 1962 NM_001166415 /// NM_001966 /// XM_006713525 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // non-traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004165 // dodecenoyl-CoA delta-isomerase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0050662 // coenzyme binding // inferred from electronic annotation 205223_at NM_014662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014662.1 /DEF=Homo sapiens KIAA0645 gene product (KIAA0645), mRNA. /FEA=mRNA /GEN=KIAA0645 /PROD=KIAA0645 gene product /DB_XREF=gi:7662221 /UG=Hs.155987 KIAA0645 gene product /FL=gb:AB014545.1 gb:NM_014662.1 NM_014662 DEP domain containing 5 DEPDC5 9681 NM_001007188 /// NM_001136029 /// NM_001242896 /// NM_001242897 /// NM_014662 /// NR_110988 /// XM_005261862 /// XM_005261863 /// XM_005261864 /// XM_005261865 /// XM_005261866 /// XM_005261867 /// XM_006724384 /// XM_006724385 /// XM_006724386 /// XM_006724387 /// XR_244404 /// XR_244405 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005096 // GTPase activator activity // inferred from electronic annotation 205224_at NM_017503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017503.1 /DEF=Homo sapiens surfeit 2 (SURF2), mRNA. /FEA=mRNA /GEN=SURF2 /PROD=surfeit 2 /DB_XREF=gi:8924249 /UG=Hs.159448 surfeit 2 /FL=gb:NM_017503.1 NM_017503 surfeit 2 SURF2 6835 NM_001278928 /// NM_017503 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 205225_at NM_000125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000125.1 /DEF=Homo sapiens estrogen receptor 1 (ESR1), mRNA. /FEA=mRNA /GEN=ESR1 /PROD=estrogen receptor 1 /DB_XREF=gi:4503602 /UG=Hs.1657 estrogen receptor 1 /FL=gb:NM_000125.1 NM_000125 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205226_at NM_006207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006207.1 /DEF=Homo sapiens platelet-derived growth factor receptor-like (PDGFRL), mRNA. /FEA=mRNA /GEN=PDGFRL /PROD=platelet-derived growth factor receptor-like /DB_XREF=gi:5453871 /UG=Hs.170040 platelet-derived growth factor receptor-like /FL=gb:NM_006207.1 gb:D37965.1 NM_006207 platelet-derived growth factor receptor-like PDGFRL 5157 NM_006207 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0004992 // platelet activating factor receptor activity // traceable author statement /// 0005019 // platelet-derived growth factor beta-receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 205227_at NM_002182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002182.1 /DEF=Homo sapiens interleukin 1 receptor accessory protein (IL1RAP), mRNA. /FEA=mRNA /GEN=IL1RAP /PROD=interleukin 1 receptor accessory protein /DB_XREF=gi:4504660 /UG=Hs.173880 interleukin 1 receptor accessory protein /FL=gb:AF029213.1 gb:AB006537.1 gb:NM_002182.1 NM_002182 interleukin 1 receptor accessory protein IL1RAP 3556 NM_001167928 /// NM_001167929 /// NM_001167930 /// NM_001167931 /// NM_002182 /// NM_134470 /// XM_005247433 /// XM_005247434 0006461 // protein complex assembly // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205228_at NM_002898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002898.1 /DEF=Homo sapiens RNA binding motif, single stranded interacting protein 2 (RBMS2), mRNA. /FEA=mRNA /GEN=RBMS2 /PROD=RNA binding motif, single stranded interactingprotein 2 /DB_XREF=gi:4506448 /UG=Hs.20938 RNA binding motif, single stranded interacting protein 2 /FL=gb:NM_002898.1 gb:D28483.1 NM_002898 RNA binding motif, single stranded interacting protein 2 RBMS2 5939 NM_002898 /// XM_005269059 /// XM_005269060 /// XM_005269061 /// XM_005269066 /// XM_006719541 /// XM_006719542 /// XM_006719543 /// XM_006719544 /// XM_006719545 0006396 // RNA processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 205229_s_at AA669336 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA669336 /FEA=EST /DB_XREF=gi:2630835 /DB_XREF=est:ad47a02.s1 /CLONE=IMAGE:884810 /UG=Hs.21016 coagulation factor C (Limulus polyphemus) homology (cochlin) /FL=gb:AF006740.1 gb:NM_004086.1 AA669336 cochlin COCH 1690 NM_001135058 /// NM_004086 /// XM_006720073 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205230_at NM_014954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014954.1 /DEF=Homo sapiens KIAA0985 protein (KIAA0985), mRNA. /FEA=mRNA /GEN=KIAA0985 /PROD=KIAA0985 protein /DB_XREF=gi:7662431 /UG=Hs.21239 KIAA0985 protein /FL=gb:AB023202.1 gb:NM_014954.1 NM_014954 rabphilin 3A homolog (mouse) RPH3A 22895 NM_001143854 /// NM_014954 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205231_s_at NM_005670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005670.1 /DEF=Homo sapiens epilepsy, progressive myoclonus type 2, Lafora disease (laforin) (EPM2A), mRNA. /FEA=mRNA /GEN=EPM2A /PROD=epilepsy, progressive myoclonus type 2, Laforadisease (laforin) /DB_XREF=gi:11321612 /UG=Hs.22464 epilepsy, progressive myoclonus type 2, Lafora disease (laforin) /FL=gb:AF284580.1 gb:NM_005670.1 gb:AF084535.2 NM_005670 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) EPM2A 7957 NM_001018041 /// NM_005670 /// XM_006715564 /// XM_006715565 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // non-traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // not recorded /// 0046959 // habituation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019203 // carbohydrate phosphatase activity // not recorded /// 0019203 // carbohydrate phosphatase activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 2001070 // starch binding // inferred from electronic annotation 205232_s_at U89386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U89386.1 /DEF=Homo sapiens serine dependent phospholipase mRNA, complete cds. /FEA=mRNA /PROD=serine dependent phospholipase /DB_XREF=gi:2529432 /UG=Hs.234392 platelet-activating factor acetylhydrolase 2 (40kD) /FL=gb:D87845.1 gb:U89386.1 gb:NM_000437.2 U89386 platelet-activating factor acetylhydrolase 2, 40kDa PAFAH2 5051 NM_000437 /// XM_006710668 /// XM_006710669 /// XM_006710670 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205233_s_at NM_000437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000437.2 /DEF=Homo sapiens platelet-activating factor acetylhydrolase 2 (40kD) (PAFAH2), mRNA. /FEA=mRNA /GEN=PAFAH2 /PROD=platelet-activating factor acetylhydrolase 2 /DB_XREF=gi:4758877 /UG=Hs.234392 platelet-activating factor acetylhydrolase 2 (40kD) /FL=gb:D87845.1 gb:U89386.1 gb:NM_000437.2 NM_000437 platelet-activating factor acetylhydrolase 2, 40kDa PAFAH2 5051 NM_000437 /// XM_006710668 /// XM_006710669 /// XM_006710670 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205234_at NM_004696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004696.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 4 (SLC16A4), mRNA. /FEA=mRNA /GEN=SLC16A4 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 4 /DB_XREF=gi:4759113 /UG=Hs.23590 solute carrier family 16 (monocarboxylic acid transporters), member 4 /FL=gb:U59185.1 gb:NM_004696.1 NM_004696 solute carrier family 16, member 4 SLC16A4 9122 NM_001201546 /// NM_001201547 /// NM_001201548 /// NM_001201549 /// NM_004696 /// XM_005271317 /// XM_005271318 /// XM_006711033 /// XR_246304 /// XR_426639 0006810 // transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 205235_s_at NM_016195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016195.1 /DEF=Homo sapiens M-phase phosphoprotein 1 (MPHOSPH1), mRNA. /FEA=mRNA /GEN=MPHOSPH1 /PROD=M-phase phosphoprotein 1 /DB_XREF=gi:7705347 /UG=Hs.240 M-phase phosphoprotein 1 /FL=gb:AL117496.1 gb:NM_016195.1 NM_016195 kinesin family member 20B KIF20B 9585 NM_001284259 /// NM_016195 0000087 // mitotic M phase // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 205236_x_at NM_003102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003102.1 /DEF=Homo sapiens superoxide dismutase 3, extracellular (SOD3), mRNA. /FEA=mRNA /GEN=SOD3 /PROD=superoxide dismutase 3, extracellular /DB_XREF=gi:4507150 /UG=Hs.2420 superoxide dismutase 3, extracellular /FL=gb:J02947.1 gb:NM_003102.1 NM_003102 superoxide dismutase 3, extracellular SOD3 6649 NM_003102 /// XR_427488 0001666 // response to hypoxia // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // not recorded /// 0046688 // response to copper ion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // /// 0005796 // Golgi lumen // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004784 // superoxide dismutase activity // not recorded /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005507 // copper ion binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // not recorded /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205237_at NM_002003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002003.2 /DEF=Homo sapiens ficolin (collagenfibrinogen domain-containing) 1 (FCN1), mRNA. /FEA=mRNA /GEN=FCN1 /PROD=ficolin 1 precursor /DB_XREF=gi:8051583 /UG=Hs.252136 ficolin (collagenfibrinogen domain-containing) 1 /FL=gb:D83920.1 gb:NM_002003.2 NM_002003 ficolin (collagen/fibrinogen domain containing) 1 FCN1 2219 NM_002003 /// XM_005263399 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0008228 // opsonization // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205238_at NM_024917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024917.1 /DEF=Homo sapiens hypothetical protein FLJ12687 (FLJ12687), mRNA. /FEA=mRNA /GEN=FLJ12687 /PROD=hypothetical protein FLJ12687 /DB_XREF=gi:13376385 /UG=Hs.263216 hypothetical protein FLJ12687 /FL=gb:NM_024917.1 NM_024917 tRNA methyltransferase 2 homolog B (S. cerevisiae) TRMT2B 79979 NM_001167970 /// NM_001167971 /// NM_001167972 /// NM_024917 /// XM_005262195 /// XM_005262196 /// XM_005262197 /// XM_005262199 /// XM_005262200 /// XM_005262201 /// XM_006724705 /// XM_006724706 /// XM_006724707 0006396 // RNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030697 // S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity // inferred from electronic annotation 205239_at NM_001657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001657.1 /DEF=Homo sapiens amphiregulin (schwannoma-derived growth factor) (AREG), mRNA. /FEA=mRNA /GEN=AREG /PROD=amphiregulin (schwannoma-derived growth factor) /DB_XREF=gi:4502198 /UG=Hs.270833 amphiregulin (schwannoma-derived growth factor) /FL=gb:M30704.1 gb:NM_001657.1 NM_001657 amphiregulin AREG 374 NM_001657 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 205240_at NM_013296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013296.1 /DEF=Homo sapiens LGN protein (HSU54999), mRNA. /FEA=mRNA /GEN=HSU54999 /PROD=LGN protein /DB_XREF=gi:9558734 /UG=Hs.278338 LGN protein /FL=gb:U54999.1 gb:NM_013296.1 NM_013296 G-protein signaling modulator 2 GPSM2 29899 NM_013296 /// XM_005270787 /// XM_006710588 /// XM_006710589 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 205241_at NM_005138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005138.1 /DEF=Homo sapiens SCO (cytochrome oxidase deficient, yeast) homolog 2 (SCO2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SCO2 /PROD=SCO (cytochrome oxidase deficient, yeast)homolog 2 /DB_XREF=gi:4826991 /UG=Hs.278431 SCO (cytochrome oxidase deficient, yeast) homolog 2 /FL=gb:NM_005138.1 NM_005138 SCO2 cytochrome c oxidase assembly protein SCO2 9997 NM_001169109 /// NM_001169110 /// NM_001169111 /// NM_005138 0000002 // mitochondrial genome maintenance // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // inferred from electronic annotation /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from direct assay 0004645 // phosphorylase activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0009032 // thymidine phosphorylase activity // inferred from electronic annotation /// 0009032 // thymidine phosphorylase activity // traceable author statement /// 0016154 // pyrimidine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205242_at NM_006419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006419.1 /DEF=Homo sapiens small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant) (SCYB13), mRNA. /FEA=mRNA /GEN=SCYB13 /PROD=small inducible cytokine B subfamily (Cys-X-Cysmotif), member 13 (B-cell chemoattractant) /DB_XREF=gi:5453576 /UG=Hs.100431 small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant) /FL=gb:AF044197.1 gb:AF029894.1 gb:NM_006419.1 NM_006419 chemokine (C-X-C motif) ligand 13 CXCL13 10563 NM_006419 /// XM_006714063 0002467 // germinal center formation // non-traceable author statement /// 0002518 // lymphocyte chemotaxis across high endothelial venule // inferred from sequence or structural similarity /// 0002544 // chronic inflammatory response // non-traceable author statement /// 0002920 // regulation of humoral immune response // non-traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred by curator /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0032861 // activation of Rap GTPase activity // inferred from sequence or structural similarity /// 0033625 // positive regulation of integrin activation // inferred from sequence or structural similarity /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035754 // B cell chemotaxis // inferred from direct assay /// 0035768 // endothelial cell chemotaxis to fibroblast growth factor // inferred from direct assay /// 0035769 // B cell chemotaxis across high endothelial venule // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from direct assay /// 0045765 // regulation of angiogenesis // non-traceable author statement /// 0048535 // lymph node development // inferred from electronic annotation /// 2000545 // negative regulation of endothelial cell chemotaxis to fibroblast growth factor // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0031724 // CXCR5 chemokine receptor binding // inferred from direct assay /// 0031735 // CCR10 chemokine receptor binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred from direct assay /// 0048248 // CXCR3 chemokine receptor binding // inferred from physical interaction 205243_at AW466889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW466889 /FEA=EST /DB_XREF=gi:7036995 /DB_XREF=est:ha04b06.x1 /CLONE=IMAGE:2872691 /UG=Hs.102867 sodium-dependent high-affinity dicarboxylate transporter 3 /FL=gb:NM_022829.1 gb:AF154121.1 AW466889 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 SLC13A3 64849 NM_001011554 /// NM_001193339 /// NM_001193340 /// NM_001193342 /// NM_022829 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015362 // high affinity sodium:dicarboxylate symporter activity // inferred from electronic annotation 205244_s_at NM_022829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022829.1 /DEF=Homo sapiens sodium-dependent high-affinity dicarboxylate transporter 3 (NADC3), mRNA. /FEA=mRNA /GEN=NADC3 /PROD=sodium-dependent high-affinity dicarboxylatetransporter 3 /DB_XREF=gi:12383071 /UG=Hs.102867 sodium-dependent high-affinity dicarboxylate transporter 3 /FL=gb:NM_022829.1 gb:AF154121.1 NM_022829 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 SLC13A3 64849 NM_001011554 /// NM_001193339 /// NM_001193340 /// NM_001193342 /// NM_022829 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015362 // high affinity sodium:dicarboxylate symporter activity // inferred from electronic annotation 205245_at NM_016948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016948.1 /DEF=Homo sapiens Tax interaction protein 40 (TAX40), mRNA. /FEA=mRNA /GEN=TAX40 /PROD=Tax interaction protein 40 /DB_XREF=gi:8394416 /UG=Hs.112933 Tax interaction protein 40 /FL=gb:AB041642.1 gb:AF252292.1 gb:AB043634.1 gb:NM_016948.1 gb:AF265565.1 NM_016948 par-6 family cell polarity regulator alpha PARD6A 50855 NM_001037281 /// NM_016948 /// XM_005255977 /// XM_006721193 /// XM_006721194 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0045217 // cell-cell junction maintenance // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0030742 // GTP-dependent protein binding // inferred from sequence or structural similarity 205246_at NM_002618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002618.1 /DEF=Homo sapiens peroxisome biogenesis factor 13 (PEX13), mRNA. /FEA=mRNA /GEN=PEX13 /PROD=peroxisome biogenesis factor 13 /DB_XREF=gi:4505722 /UG=Hs.115240 peroxisome biogenesis factor 13 /FL=gb:AF048755.1 gb:U71374.1 gb:NM_002618.1 gb:AB022192.1 NM_002618 peroxisomal biogenesis factor 13 PEX13 5194 NM_002618 0001561 // fatty acid alpha-oxidation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016560 // protein import into peroxisome matrix, docking // inferred from mutant phenotype /// 0016560 // protein import into peroxisome matrix, docking // traceable author statement /// 0021795 // cerebral cortex cell migration // inferred from sequence or structural similarity /// 0060152 // microtubule-based peroxisome localization // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205247_at AI743713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743713 /FEA=EST /DB_XREF=gi:5112001 /DB_XREF=est:wg53a06.x1 /CLONE=IMAGE:2368786 /UG=Hs.11689 Notch (Drosophila) homolog 4 /FL=gb:U95299.1 gb:NM_004557.1 AI743713 notch 4 NOTCH4 4855 NM_004557 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001709 // cell fate determination // traceable author statement /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007221 // positive regulation of transcription of Notch receptor target // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030879 // mammary gland development // inferred from direct assay /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // non-traceable author statement /// 0045602 // negative regulation of endothelial cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050793 // regulation of developmental process // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // traceable author statement 205248_at NM_005128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005128.1 /DEF=Homo sapiens chromosome 21 open reading frame 5 (C21ORF5), mRNA. /FEA=mRNA /GEN=C21ORF5 /PROD=chromosome 21 open reading frame 5 /DB_XREF=gi:4826652 /UG=Hs.129781 chromosome 21 open reading frame 5 /FL=gb:NM_005128.1 NM_005128 dopey family member 2 DOPEY2 9980 NM_005128 /// XM_006724068 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 205249_at NM_000399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000399.2 /DEF=Homo sapiens early growth response 2 (Krox-20 (Drosophila) homolog) (EGR2), mRNA. /FEA=mRNA /GEN=EGR2 /PROD=early growth response 2 protein /DB_XREF=gi:9845523 /UG=Hs.1395 early growth response 2 (Krox-20 (Drosophila) homolog) /FL=gb:J04076.1 gb:AF139463.1 gb:NM_000399.2 NM_000399 early growth response 2 EGR2 1959 NM_000399 /// NM_001136177 /// NM_001136178 /// NM_001136179 /// XM_005269590 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0007420 // brain development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007622 // rhythmic behavior // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0021569 // rhombomere 3 development // inferred from electronic annotation /// 0021612 // facial nerve structural organization // inferred from electronic annotation /// 0021660 // rhombomere 3 formation // inferred from electronic annotation /// 0021666 // rhombomere 5 formation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035284 // brain segmentation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042552 // myelination // not recorded /// 0043066 // negative regulation of apoptotic process // not recorded /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // not recorded /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071371 // cellular response to gonadotropin stimulus // not recorded 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 205250_s_at NM_014684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014684.1 /DEF=Homo sapiens KIAA0373 gene product (KIAA0373), mRNA. /FEA=mRNA /GEN=KIAA0373 /PROD=KIAA0373 gene product /DB_XREF=gi:7662079 /UG=Hs.150444 KIAA0373 gene product /FL=gb:AB002371.1 gb:NM_014684.1 NM_014684 centrosomal protein 290kDa CEP290 80184 NM_025114 /// XM_005269158 /// XM_005269160 /// XM_005269161 /// XM_006719609 /// XM_006719610 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0015031 // protein transport // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0070201 // regulation of establishment of protein localization // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0034451 // centriolar satellite // inferred from direct assay /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051011 // microtubule minus-end binding // inferred from direct assay 205251_at NM_022817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022817.1 /DEF=Homo sapiens period (Drosophila) homolog 2 (PER2), transcript variant 1, mRNA. /FEA=mRNA /GEN=PER2 /PROD=period 2, isoform 2 /DB_XREF=gi:12707561 /UG=Hs.153405 period (Drosophila) homolog 2 /FL=gb:NM_022817.1 NM_022817 period circadian clock 2 PER2 8864 NM_003894 /// NM_022817 /// XM_005246111 /// XM_006712824 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from sequence or structural similarity /// 0019249 // lactate biosynthetic process // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 0051946 // regulation of glutamate uptake involved in transmission of nerve impulse // inferred from sequence or structural similarity /// 0070345 // negative regulation of fat cell proliferation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from sequence or structural similarity /// 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity 205252_at NM_003450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003450.1 /DEF=Homo sapiens zinc finger protein 174 (ZNF174), mRNA. /FEA=mRNA /GEN=ZNF174 /PROD=zinc finger protein 174 /DB_XREF=gi:4508006 /UG=Hs.155204 zinc finger protein 174 /FL=gb:U31248.1 gb:NM_003450.1 NM_003450 zinc finger protein 174 ZNF174 7727 NM_001032292 /// NM_003450 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205253_at NM_002585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002585.1 /DEF=Homo sapiens pre-B-cell leukemia transcription factor 1 (PBX1), mRNA. /FEA=mRNA /GEN=PBX1 /PROD=pre-B-cell leukemia transcription factor 1 /DB_XREF=gi:4505622 /UG=Hs.155691 pre-B-cell leukemia transcription factor 1 /FL=gb:M86546.1 gb:NM_002585.1 NM_002585 pre-B-cell leukemia homeobox 1 PBX1 5087 NM_001204961 /// NM_001204963 /// NM_002585 /// XM_005245228 /// XM_005245229 /// XM_005245230 /// XM_006711347 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 205254_x_at AW027359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027359 /FEA=EST /DB_XREF=gi:5886115 /DB_XREF=est:wt73f08.x1 /CLONE=IMAGE:2513127 /UG=Hs.169294 transcription factor 7 (T-cell specific, HMG-box) /FL=gb:NM_003202.1 AW027359 transcription factor 7 (T-cell specific, HMG-box) TCF7 6932 NM_001134851 /// NM_001134852 /// NM_003202 /// NM_201632 /// NM_201634 /// NM_213648 /// NR_033449 /// XM_006714678 /// XM_006714679 /// XM_006714680 /// XM_006714681 /// XM_006714682 /// XM_006714683 /// XM_006714684 /// XM_006714685 /// XM_006714686 /// XM_006714687 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006955 // immune response // traceable author statement /// 0007420 // brain development // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // not recorded /// 0060070 // canonical Wnt signaling pathway // not recorded /// 0071353 // cellular response to interleukin-4 // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 205255_x_at NM_003202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003202.1 /DEF=Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7), mRNA. /FEA=mRNA /GEN=TCF7 /PROD=transcription factor 7 (T-cell specific,HMG-box) /DB_XREF=gi:4507402 /UG=Hs.169294 transcription factor 7 (T-cell specific, HMG-box) /FL=gb:NM_003202.1 NM_003202 transcription factor 7 (T-cell specific, HMG-box) TCF7 6932 NM_001134851 /// NM_001134852 /// NM_003202 /// NM_201632 /// NM_201634 /// NM_213648 /// NR_033449 /// XM_006714678 /// XM_006714679 /// XM_006714680 /// XM_006714681 /// XM_006714682 /// XM_006714683 /// XM_006714684 /// XM_006714685 /// XM_006714686 /// XM_006714687 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006955 // immune response // traceable author statement /// 0007420 // brain development // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // not recorded /// 0060070 // canonical Wnt signaling pathway // not recorded /// 0071353 // cellular response to interleukin-4 // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 205256_at NM_014830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014830.1 /DEF=Homo sapiens KIAA0352 gene product (KIAA0352), mRNA. /FEA=mRNA /GEN=KIAA0352 /PROD=KIAA0352 gene product /DB_XREF=gi:7662071 /UG=Hs.17262 KIAA0352 gene product /FL=gb:AB002350.1 gb:NM_014830.1 NM_014830 zinc finger and BTB domain containing 39 ZBTB39 9880 NM_014830 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205257_s_at NM_001635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001635.1 /DEF=Homo sapiens amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen) (AMPH), mRNA. /FEA=mRNA /GEN=AMPH /PROD=amphiphysin /DB_XREF=gi:4502080 /UG=Hs.173034 amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen) /FL=gb:NM_001635.1 gb:U07616.1 NM_001635 amphiphysin AMPH 273 NM_001635 /// NM_139316 /// XM_006715689 /// XM_006715690 /// XM_006715691 0006897 // endocytosis // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 205258_at NM_002193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002193.1 /DEF=Homo sapiens inhibin, beta B (activin AB beta polypeptide) (INHBB), mRNA. /FEA=mRNA /GEN=INHBB /PROD=inhibin beta B subunit precursor /DB_XREF=gi:9257224 /UG=Hs.1735 inhibin, beta B (activin AB beta polypeptide) /FL=gb:NM_002193.1 NM_002193 inhibin, beta B INHBB 3625 NM_002193 0001541 // ovarian follicle development // non-traceable author statement /// 0006952 // defense response // traceable author statement /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from direct assay /// 0030154 // cell differentiation // non-traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044320 // cellular response to leptin stimulus // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from sequence or structural similarity /// 0046881 // positive regulation of follicle-stimulating hormone secretion // inferred from physical interaction /// 0046882 // negative regulation of follicle-stimulating hormone secretion // inferred from physical interaction /// 0048178 // negative regulation of hepatocyte growth factor biosynthetic process // inferred from direct assay /// 0048599 // oocyte development // inferred from electronic annotation /// 0060279 // positive regulation of ovulation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005125 // cytokine activity // traceable author statement /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046789 // host cell surface receptor binding // traceable author statement 205259_at NM_000901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000901.1 /DEF=Homo sapiens nuclear receptor subfamily 3, group C, member 2 (NR3C2), mRNA. /FEA=mRNA /GEN=NR3C2 /PROD=nuclear receptor subfamily 3, group C, member 2 /DB_XREF=gi:4505198 /UG=Hs.1790 nuclear receptor subfamily 3, group C, member 2 /FL=gb:M16801.1 gb:NM_000901.1 NM_000901 nuclear receptor subfamily 3, group C, member 2 NR3C2 4306 NM_000901 /// NM_001166104 /// XM_005263014 /// XM_006714222 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007588 // excretion // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205260_s_at NM_001107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001107.1 /DEF=Homo sapiens acylphosphatase 1, erythrocyte (common) type (ACYP1), mRNA. /FEA=mRNA /GEN=ACYP1 /PROD=erythrocyte acylphosphatase 1 /DB_XREF=gi:4557244 /UG=Hs.18573 acylphosphatase 1, erythrocyte (common) type /FL=gb:NM_001107.1 NM_001107 acylphosphatase 1, erythrocyte (common) type ACYP1 97 NM_001107 /// NM_203488 /// XM_005268239 /// XM_005268240 /// XM_006720335 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0003998 // acylphosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation 205261_at NM_002630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002630.1 /DEF=Homo sapiens progastricsin (pepsinogen C) (PGC), mRNA. /FEA=mRNA /GEN=PGC /PROD=progastricsin (pepsinogen C) /DB_XREF=gi:4505756 /UG=Hs.1867 progastricsin (pepsinogen C) /FL=gb:U75272.1 gb:NM_002630.1 gb:J04443.1 NM_002630 progastricsin (pepsinogen C) PGC 5225 NM_001166424 /// NM_002630 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205262_at NM_000238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000238.1 /DEF=Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2), mRNA. /FEA=mRNA /GEN=KCNH2 /PROD=potassium voltage-gated channel, subfamily H,member 2 /DB_XREF=gi:4557728 /UG=Hs.188021 potassium voltage-gated channel, subfamily H (eag-related), member 2 /FL=gb:NM_000238.1 gb:U04270.1 NM_000238 potassium voltage-gated channel, subfamily H (eag-related), member 2 KCNH2 3757 NM_000238 /// NM_001204798 /// NM_172056 /// NM_172057 /// XM_006715977 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0003064 // regulation of heart rate by hormone // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0055075 // potassium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902303 // negative regulation of potassium ion export // inferred from direct assay 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 205263_at AF082283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF082283.1 /DEF=Homo sapiens CARD-containing apoptotic signaling protein (BCL10) mRNA, complete cds. /FEA=mRNA /GEN=BCL10 /PROD=CARD-containing apoptotic signaling protein /DB_XREF=gi:4092066 /UG=Hs.193516 B-cell CLLlymphoma 10 /FL=gb:AF082283.1 gb:AF057700.1 gb:AF100338.1 gb:NM_003921.1 gb:AF127386.1 gb:AF134395.1 gb:AF105066.1 AF082283 B-cell CLL/lymphoma 10 BCL10 8915 NM_003921 /// XM_005271311 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // inferred by curator /// 0002237 // response to molecule of bacterial origin // inferred from expression pattern /// 0002250 // adaptive immune response // traceable author statement /// 0002906 // negative regulation of mature B cell apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // inferred from direct assay /// 0006968 // cellular defense response // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0009620 // response to fungus // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032094 // response to food // inferred from direct assay /// 0032765 // positive regulation of mast cell cytokine production // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042109 // lymphotoxin A biosynthetic process // non-traceable author statement /// 0042221 // response to chemical // inferred from direct assay /// 0042226 // interleukin-6 biosynthetic process // non-traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051259 // protein oligomerization // inferred from physical interaction /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // traceable author statement /// 0070231 // T cell apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032449 // CBM complex // non-traceable author statement /// 0042101 // T cell receptor complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from direct assay 205264_at NM_012099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012099.1 /DEF=Homo sapiens CD3-epsilon-associated protein; antisense to ERCC-1 (ASE-1), mRNA. /FEA=mRNA /GEN=ASE-1 /PROD=CD3-epsilon-associated protein; antisense toERCC-1 /DB_XREF=gi:6912245 /UG=Hs.211956 CD3-epsilon-associated protein; antisense to ERCC-1 /FL=gb:U86751.1 gb:AF017633.1 gb:NM_012099.1 NM_012099 CD3e molecule, epsilon associated protein CD3EAP 10849 NM_012099 /// XM_005258425 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0009303 // rRNA transcription // inferred from electronic annotation 0000120 // RNA polymerase I transcription factor complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205265_s_at NM_005876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005876.1 /DEF=Homo sapiens nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury (APEG1), mRNA. /FEA=mRNA /GEN=APEG1 /PROD=nuclear protein, marker for differentiatedaortic smooth muscle and down-regulated with vascularinjury /DB_XREF=gi:5031588 /UG=Hs.21639 nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury /FL=gb:U57099.1 gb:NM_005876.1 NM_005876 CAVP-target protein-like /// SPEG complex locus LOC100996693 /// SPEG 10290 /// 100996693 NM_001173476 /// NM_001286811 /// NM_005876 /// XM_005246235 /// XM_005246236 /// XM_005246237 /// XM_005246238 /// XM_005246239 /// XM_005246240 /// XM_005246241 /// XM_005246242 /// XM_006712187 /// XM_006712188 /// XM_006712189 /// XM_006712190 /// XM_006712191 /// XM_006712192 /// XM_006712193 /// XM_006712194 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060541 // respiratory system development // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205266_at NM_002309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002309.2 /DEF=Homo sapiens leukemia inhibitory factor (cholinergic differentiation factor) (LIF), mRNA. /FEA=mRNA /GEN=LIF /PROD=leukemia inhibitory factor (cholinergicdifferentiation factor) /DB_XREF=gi:6006018 /UG=Hs.2250 leukemia inhibitory factor (cholinergic differentiation factor) /FL=gb:NM_002309.2 NM_002309 leukemia inhibitory factor LIF 3976 NM_001257135 /// NM_002309 /// XM_005261601 /// XM_006724240 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // inferred from direct assay /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046697 // decidualization // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from direct assay /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from direct assay /// 1900182 // positive regulation of protein localization to nucleus // inferred from direct assay /// 1901676 // positive regulation of histone H3-K27 acetylation // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay 0001135 // RNA polymerase II transcription factor recruiting transcription factor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005146 // leukemia inhibitory factor receptor binding // inferred from direct assay /// 0005146 // leukemia inhibitory factor receptor binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 205267_at NM_006235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006235.1 /DEF=Homo sapiens POU domain, class 2, associating factor 1 (POU2AF1), mRNA. /FEA=mRNA /GEN=POU2AF1 /PROD=POU domain, class 2, associating factor 1 /DB_XREF=gi:5453933 /UG=Hs.2407 POU domain, class 2, associating factor 1 /FL=gb:NM_006235.1 NM_006235 uncharacterized LOC101928620 /// POU class 2 associating factor 1 LOC101928620 /// POU2AF1 5450 /// 101928620 NM_006235 /// XM_005271593 /// XM_005271594 /// XM_006718859 /// XM_006718860 /// XR_246466 /// XR_247729 /// XR_252961 /// XR_424280 /// XR_428994 /// XR_432748 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205268_s_at NM_017488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017488.1 /DEF=Homo sapiens adducin 2 (beta) (ADD2), transcript variant beta-4, mRNA. /FEA=mRNA /GEN=ADD2 /PROD=adducin 2, isoform e /DB_XREF=gi:9257189 /UG=Hs.247423 adducin 2 (beta) /FL=gb:NM_017488.1 NM_017488 adducin 2 (beta) ADD2 119 NM_001185054 /// NM_001185055 /// NM_001617 /// NM_017482 /// NM_017483 /// NM_017484 /// NM_017485 /// NM_017486 /// NM_017487 /// NM_017488 0006461 // protein complex assembly // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 205269_at AI123251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123251 /FEA=EST /DB_XREF=gi:3539017 /DB_XREF=est:qa47g03.x1 /CLONE=IMAGE:1689940 /UG=Hs.2488 lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) /FL=gb:NM_005565.2 gb:U20158.1 AI123251 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) LCP2 3937 NM_005565 0006955 // immune response // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 205270_s_at NM_005565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005565.2 /DEF=Homo sapiens lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) (LCP2), mRNA. /FEA=mRNA /GEN=LCP2 /PROD=lymphocyte cytosolic protein 2 /DB_XREF=gi:7382491 /UG=Hs.2488 lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) /FL=gb:NM_005565.2 gb:U20158.1 NM_005565 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) LCP2 3937 NM_005565 0006955 // immune response // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 205271_s_at NM_012119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012119.1 /DEF=Homo sapiens cell cycle related kinase (CCRK), mRNA. /FEA=mRNA /GEN=CCRK /PROD=cell cycle related kinase /DB_XREF=gi:7106268 /UG=Hs.26322 cell cycle related kinase /FL=gb:AF035013.1 gb:NM_012119.1 NM_012119 cyclin-dependent kinase 20 CDK20 23552 NM_001039803 /// NM_001170639 /// NM_001170640 /// NM_012119 /// NM_178432 /// XM_005251860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205272_s_at NM_006250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006250.1 /DEF=Homo sapiens proline-rich protein HaeIII subfamily 1 (PRH1), mRNA. /FEA=mRNA /GEN=PRH1 /PROD=proline-rich protein HaeIII subfamily 1 /DB_XREF=gi:9945309 /UG=Hs.278469 proline-rich protein HaeIII subfamily 1 /FL=gb:NM_006250.1 NM_006250 proline-rich protein HaeIII subfamily 1 /// PRH1-PRR4 readthrough /// proline-rich protein HaeIII subfamily 2 PRH1 /// PRH1-PRR4 /// PRH2 5554 /// 5555 /// 100533464 NM_001110213 /// NM_001291314 /// NM_001291315 /// NM_005042 /// NM_006250 /// NR_037918 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0005515 // protein binding // inferred from physical interaction 205273_s_at NM_014968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014968.1 /DEF=Homo sapiens KIAA1104 protein (KIAA1104), mRNA. /FEA=mRNA /GEN=KIAA1104 /PROD=KIAA1104 protein /DB_XREF=gi:7662487 /UG=Hs.279039 KIAA1104 protein /FL=gb:AB029027.1 gb:NM_014968.1 NM_014968 pitrilysin metallopeptidase 1 PITRM1 10531 NM_001242307 /// NM_001242309 /// NM_014889 /// NM_014968 /// XM_005252345 /// XM_006717362 /// XR_428633 0006508 // proteolysis // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205274_at U87964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U87964.1 /DEF=Human putative G-protein (GP-1) mRNA, complete cds. /FEA=mRNA /GEN=GP-1 /PROD=putative G-protein /DB_XREF=gi:1916924 /UG=Hs.283677 GTP binding protein 1 /FL=gb:U87964.1 gb:NM_004286.1 U87964 GTP binding protein 1 GTPBP1 9567 NM_004286 /// XM_005261857 /// XR_244397 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0061014 // positive regulation of mRNA catabolic process // inferred from sequence or structural similarity 0000177 // cytoplasmic exosome (RNase complex) // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205275_at BE866976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE866976 /FEA=EST /DB_XREF=gi:10315752 /DB_XREF=est:601442806F1 /CLONE=IMAGE:3847057 /UG=Hs.283677 GTP binding protein 1 /FL=gb:U87964.1 gb:NM_004286.1 BE866976 GTP binding protein 1 GTPBP1 9567 NM_004286 /// XM_005261857 /// XR_244397 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0061014 // positive regulation of mRNA catabolic process // inferred from sequence or structural similarity 0000177 // cytoplasmic exosome (RNase complex) // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205276_s_at NM_004286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004286.1 /DEF=Homo sapiens GTP binding protein 1 (GTPBP1), mRNA. /FEA=mRNA /GEN=GTPBP1 /PROD=GTP binding protein 1 /DB_XREF=gi:4758489 /UG=Hs.283677 GTP binding protein 1 /FL=gb:U87964.1 gb:NM_004286.1 NM_004286 GTP binding protein 1 GTPBP1 9567 NM_004286 /// XM_005261857 /// XR_244397 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0061014 // positive regulation of mRNA catabolic process // inferred from sequence or structural similarity 0000177 // cytoplasmic exosome (RNase complex) // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205277_at NM_012231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012231.1 /DEF=Homo sapiens PR domain containing 2, with ZNF domain (PRDM2), mRNA. /FEA=mRNA /GEN=PRDM2 /PROD=PR domain containing 2, with ZNF domain /DB_XREF=gi:10092605 /UG=Hs.289024 PR domain containing 2, with ZNF domain /FL=gb:NM_012231.1 gb:U17838.1 NM_012231 PR domain containing 2, with ZNF domain PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205278_at NM_000817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000817.1 /DEF=Homo sapiens glutamate decarboxylase 1 (brain, 67kD) (GAD1), transcript variant GAD67, mRNA. /FEA=mRNA /GEN=GAD1 /PROD=glutamate decarboxylase 1, isoform GAD67 /DB_XREF=gi:4503872 /UG=Hs.324784 glutamate decarboxylase 1 (brain, 67kD) /FL=gb:M81883.1 gb:L16888.1 gb:NM_000817.1 NM_000817 glutamate decarboxylase 1 (brain, 67kDa) GAD1 2571 NM_000817 /// NM_013445 /// XM_005246443 /// XM_005246444 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006540 // glutamate decarboxylation to succinate // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009449 // gamma-aminobutyric acid biosynthetic process // inferred from electronic annotation /// 0018352 // protein-pyridoxal-5-phosphate linkage // traceable author statement /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0012506 // vesicle membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 205279_s_at AF094754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF094754.1 /DEF=Homo sapiens glycine receptor beta subunit precursor (GLRB), variant A mRNA, complete cds. /FEA=mRNA /GEN=GLRB /PROD=glycine receptor beta subunit precursor /DB_XREF=gi:3834634 /UG=Hs.32973 glycine receptor, beta /FL=gb:AF094754.1 gb:NM_000824.1 gb:U33267.1 AF094754 glycine receptor, beta GLRB 2743 NM_000824 /// NM_001166060 /// NM_001166061 0001964 // startle response // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // inferred from mutant phenotype /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060012 // synaptic transmission, glycinergic // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016933 // extracellular-glycine-gated ion channel activity // inferred from mutant phenotype /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from direct assay /// 0016934 // extracellular-glycine-gated chloride channel activity // traceable author statement 205280_at NM_000824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000824.1 /DEF=Homo sapiens glycine receptor, beta (GLRB), mRNA. /FEA=mRNA /GEN=GLRB /PROD=glycine receptor, beta /DB_XREF=gi:4504022 /UG=Hs.32973 glycine receptor, beta /FL=gb:AF094754.1 gb:NM_000824.1 gb:U33267.1 NM_000824 glycine receptor, beta GLRB 2743 NM_000824 /// NM_001166060 /// NM_001166061 0001964 // startle response // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // inferred from mutant phenotype /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060012 // synaptic transmission, glycinergic // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016933 // extracellular-glycine-gated ion channel activity // inferred from mutant phenotype /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from direct assay /// 0016934 // extracellular-glycine-gated chloride channel activity // traceable author statement 205281_s_at NM_002641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002641.1 /DEF=Homo sapiens phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) (PIGA), transcript variant 1, mRNA. /FEA=mRNA /GEN=PIGA /PROD=phosphatidylinositol glycan, class A isoform 1 /DB_XREF=gi:11863129 /UG=Hs.51 phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) /FL=gb:NM_002641.1 gb:D11466.1 NM_002641 phosphatidylinositol glycan anchor biosynthesis, class A PIGA 5277 NM_002641 /// NM_020472 /// NM_020473 /// NR_033835 /// NR_033836 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009893 // positive regulation of metabolic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // traceable author statement 205282_at NM_004631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004631.1 /DEF=Homo sapiens low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), mRNA. /FEA=mRNA /GEN=LRP8 /PROD=low density lipoprotein receptor-related protein8, apolipoprotein e receptor /DB_XREF=gi:4758687 /UG=Hs.54481 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor /FL=gb:D50678.1 gb:NM_004631.1 NM_004631 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor LRP8 7804 NM_001018054 /// NM_004631 /// NM_017522 /// NM_033300 /// XM_005271173 /// XM_005271174 /// XM_005271175 /// XM_005271176 /// XM_006710881 /// XM_006710882 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001523 // retinoid metabolic process // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006897 // endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0021541 // ammon gyrus development // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0038026 // reelin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred by curator /// 0038025 // reelin receptor activity // inferred from sequence or structural similarity 205283_at NM_006731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006731.1 /DEF=Homo sapiens Fukuyama type congenital muscular dystrophy (FCMD), mRNA. /FEA=mRNA /GEN=FCMD /PROD=fukutin /DB_XREF=gi:5803014 /UG=Hs.55777 Fukuyama type congenital muscular dystrophy /FL=gb:AB008226.1 gb:NM_006731.1 NM_006731 fukutin FKTN 2218 NM_001079802 /// NM_001198963 /// NM_006731 /// XM_005251803 /// XM_005251804 /// XM_006717006 /// XM_006717007 /// XM_006717008 /// XM_006717009 /// XM_006717010 /// XM_006717011 /// XM_006717012 /// XM_006717013 /// XM_006717014 0007399 // nervous system development // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0060049 // regulation of protein glycosylation // non-traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation 205284_at NM_014777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014777.1 /DEF=Homo sapiens KIAA0133 gene product (KIAA0133), mRNA. /FEA=mRNA /GEN=KIAA0133 /PROD=KIAA0133 gene product /DB_XREF=gi:7661931 /UG=Hs.57730 KIAA0133 gene product /FL=gb:D50923.1 gb:NM_014777.1 NM_014777 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) URB2 9816 NM_014777 /// XM_005273360 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 205285_s_at AI633888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633888 /FEA=EST /DB_XREF=gi:4685218 /DB_XREF=est:tt04g01.x1 /CLONE=IMAGE:2239824 /UG=Hs.58435 FYN-binding protein (FYB-120130) /FL=gb:U93049.1 gb:AF001862.1 gb:NM_001465.1 AI633888 FYN binding protein FYB 2533 NM_001243093 /// NM_001465 /// NM_199335 /// XM_006714464 /// XM_006714465 /// XM_006714466 0006468 // protein phosphorylation // traceable author statement /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 205286_at U85658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85658.1 /DEF=Human transcription factor ERF-1 mRNA, complete cds. /FEA=mRNA /PROD=ERF-1 /DB_XREF=gi:2058552 /UG=Hs.61796 transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) /FL=gb:U85658.1 gb:NM_003222.1 U85658 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) TFAP2C 7022 NM_003222 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0060598 // dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from direct assay 205287_s_at NM_003222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003222.1 /DEF=Homo sapiens transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) (TFAP2C), mRNA. /FEA=mRNA /GEN=TFAP2C /PROD=transcription factor AP-2 gamma (activatingenhancer-binding protein 2 gamma) /DB_XREF=gi:4507444 /UG=Hs.61796 transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) /FL=gb:U85658.1 gb:NM_003222.1 NM_003222 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) TFAP2C 7022 NM_003222 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0060598 // dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from direct assay 205288_at NM_003672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003672.1 /DEF=Homo sapiens CDC14 (cell division cycle 14, S. cerevisiae) homolog A (CDC14A), mRNA. /FEA=mRNA /GEN=CDC14A /PROD=CDC14 (cell division cycle 14, S. cerevisiae)homolog A /DB_XREF=gi:4502696 /UG=Hs.65993 CDC14 (cell division cycle 14, S. cerevisiae) homolog A /FL=gb:AF000367.1 gb:NM_003672.1 gb:AF122013.1 NM_003672 cell division cycle 14A CDC14A 8556 NM_003672 /// NM_033312 /// NM_033313 /// XM_005271294 /// XM_005271296 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 205289_at AA583044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA583044 /FEA=EST /DB_XREF=gi:2360404 /DB_XREF=est:nn80f11.s1 /CLONE=IMAGE:1090221 /UG=Hs.73853 bone morphogenetic protein 2 /FL=gb:NM_001200.1 AA583044 bone morphogenetic protein 2 BMP2 650 NM_001200 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003130 // BMP signaling pathway involved in heart induction // inferred from direct assay /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0010922 // positive regulation of phosphatase activity // inferred from direct assay /// 0021537 // telencephalon development // inferred from direct assay /// 0021978 // telencephalon regionalization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from expression pattern /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0033690 // positive regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035051 // cardiocyte differentiation // inferred from direct assay /// 0035051 // cardiocyte differentiation // inferred from mutant phenotype /// 0035054 // embryonic heart tube anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042482 // positive regulation of odontogenesis // inferred from sequence or structural similarity /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0051042 // negative regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from sequence or structural similarity /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from sequence or structural similarity /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060485 // mesenchyme development // inferred from mutant phenotype /// 0060804 // positive regulation of Wnt signaling pathway by BMP signaling pathway // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from expression pattern /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000726 // negative regulation of cardiac muscle cell differentiation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay 0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from direct assay 205290_s_at NM_001200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001200.1 /DEF=Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA. /FEA=mRNA /GEN=BMP2 /PROD=bone morphogenetic protein 2 precursor /DB_XREF=gi:4557368 /UG=Hs.73853 bone morphogenetic protein 2 /FL=gb:NM_001200.1 NM_001200 bone morphogenetic protein 2 BMP2 650 NM_001200 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003130 // BMP signaling pathway involved in heart induction // inferred from direct assay /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0010922 // positive regulation of phosphatase activity // inferred from direct assay /// 0021537 // telencephalon development // inferred from direct assay /// 0021978 // telencephalon regionalization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from expression pattern /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0033690 // positive regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035051 // cardiocyte differentiation // inferred from direct assay /// 0035051 // cardiocyte differentiation // inferred from mutant phenotype /// 0035054 // embryonic heart tube anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042482 // positive regulation of odontogenesis // inferred from sequence or structural similarity /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0051042 // negative regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from sequence or structural similarity /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from sequence or structural similarity /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060485 // mesenchyme development // inferred from mutant phenotype /// 0060804 // positive regulation of Wnt signaling pathway by BMP signaling pathway // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from expression pattern /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000726 // negative regulation of cardiac muscle cell differentiation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay 0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from direct assay 205291_at NM_000878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000878.1 /DEF=Homo sapiens interleukin 2 receptor, beta (IL2RB), mRNA. /FEA=mRNA /GEN=IL2RB /PROD=interleukin 2 receptor, beta /DB_XREF=gi:4504664 /UG=Hs.75596 interleukin 2 receptor, beta /FL=gb:M26062.1 gb:NM_000878.1 NM_000878 interleukin 2 receptor, beta IL2RB 3560 NM_000878 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0038110 // interleukin-2-mediated signaling pathway // inferred from direct assay /// 0038110 // interleukin-2-mediated signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004911 // interleukin-2 receptor activity // inferred from direct assay /// 0004911 // interleukin-2 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019976 // interleukin-2 binding // inferred from sequence or structural similarity 205292_s_at NM_002137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002137.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A2B1 (HNRPA2B1), mRNA. /FEA=mRNA /GEN=HNRPA2B1 /PROD=heterogeneous nuclear ribonucleoprotein A2B1 /DB_XREF=gi:4504446 /UG=Hs.75598 heterogeneous nuclear ribonucleoprotein A2B1 /FL=gb:NM_002137.1 NM_002137 heterogeneous nuclear ribonucleoprotein A2/B1 HNRNPA2B1 3181 NM_002137 /// NM_031243 /// XM_005249729 /// XM_006715714 /// XR_242076 /// XR_242077 /// XR_428077 /// XR_428078 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from electronic annotation /// 0050658 // RNA transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097157 // pre-mRNA intronic binding // inferred from electronic annotation 205293_x_at AB017120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017120.1 /DEF=Homo sapiens mRNA for insulin receptor substrate protein of 53 kDa (a shorter form), complete cds. /FEA=mRNA /PROD=insulin receptor substrate protein of 53 kDa (ashorter form) /DB_XREF=gi:4239983 /UG=Hs.7936 BAI1-associated protein 2 /FL=gb:AB015019.1 gb:AB017120.1 gb:NM_017450.1 AB017120 BAI1-associated protein 2 BAIAP2 10458 NM_001144888 /// NM_006340 /// NM_017450 /// NM_017451 /// XM_005256943 /// XM_005256944 /// XM_005256945 /// XM_005256948 /// XM_006721635 /// XM_006721636 /// XM_006721637 /// XM_006721638 /// XR_429867 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 205294_at NM_017450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017450.1 /DEF=Homo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=BAIAP2 /PROD=BAI1-associated protein 2, isoform 1 /DB_XREF=gi:9257196 /UG=Hs.7936 BAI1-associated protein 2 /FL=gb:AB015019.1 gb:AB017120.1 gb:NM_017450.1 NM_017450 BAI1-associated protein 2 BAIAP2 10458 NM_001144888 /// NM_006340 /// NM_017450 /// NM_017451 /// XM_005256943 /// XM_005256944 /// XM_005256945 /// XM_005256948 /// XM_006721635 /// XM_006721636 /// XM_006721637 /// XM_006721638 /// XR_429867 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 205295_at NM_001825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001825.1 /DEF=Homo sapiens creatine kinase, mitochondrial 2 (sarcomeric) (CKMT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CKMT2 /PROD=sarcomeric mitochondrial creatine kinaseprecursor /DB_XREF=gi:4502854 /UG=Hs.80691 creatine kinase, mitochondrial 2 (sarcomeric) /FL=gb:J05401.1 gb:NM_001825.1 NM_001825 creatine kinase, mitochondrial 2 (sarcomeric) CKMT2 1160 NM_001099735 /// NM_001099736 /// NM_001825 /// XM_005248420 0006600 // creatine metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205296_at AL365505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL365505 /DEF=Human DNA sequence from clone RP11-382A12 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands. Contains the 5 part of the gene for a 72.1 KDa protein (DKFZP564A032, SBBI88) similar to mouse IFN-gamma induced MG11 and the 3 part of the RBL... /FEA=mRNA /DB_XREF=gi:11558572 /UG=Hs.87 retinoblastoma-like 1 (p107) /FL=gb:L14812.1 gb:NM_002895.1 AL365505 retinoblastoma-like 1 RBL1 5933 NM_002895 /// NM_183404 /// XM_006723842 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction 205297_s_at NM_000626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000626.1 /DEF=Homo sapiens CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 1, mRNA. /FEA=mRNA /GEN=CD79B /PROD=CD79B antigen, isoform 1 precursor /DB_XREF=gi:11038673 /UG=Hs.89575 CD79B antigen (immunoglobulin-associated beta) /FL=gb:NM_000626.1 gb:M80461.1 gb:M89957.1 NM_000626 CD79b molecule, immunoglobulin-associated beta CD79B 974 NM_000626 /// NM_001039933 /// NM_021602 /// XM_005257858 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019815 // B cell receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205298_s_at W58757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W58757 /FEA=EST /DB_XREF=gi:1364334 /DB_XREF=est:zd24d07.s1 /CLONE=IMAGE:341581 /UG=Hs.91813 butyrophilin, subfamily 2, member A2 /FL=gb:U90550.1 gb:NM_006995.2 W58757 butyrophilin, subfamily 2, member A2 BTN2A2 10385 NM_001197237 /// NM_001197238 /// NM_001197239 /// NM_001197240 /// NM_006995 /// NM_181531 /// XM_005248797 /// XM_005248798 /// XM_006714953 /// XM_006714954 /// XM_006714955 /// XM_006714956 0031324 // negative regulation of cellular metabolic process // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 205299_s_at NM_006995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006995.2 /DEF=Homo sapiens butyrophilin, subfamily 2, member A2 (BTN2A2), mRNA. /FEA=mRNA /GEN=BTN2A2 /PROD=butyrophilin, subfamily 2, member A2 /DB_XREF=gi:6453812 /UG=Hs.91813 butyrophilin, subfamily 2, member A2 /FL=gb:U90550.1 gb:NM_006995.2 NM_006995 butyrophilin, subfamily 2, member A2 BTN2A2 10385 NM_001197237 /// NM_001197238 /// NM_001197239 /// NM_001197240 /// NM_006995 /// NM_181531 /// XM_005248797 /// XM_005248798 /// XM_006714953 /// XM_006714954 /// XM_006714955 /// XM_006714956 0031324 // negative regulation of cellular metabolic process // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 205300_s_at NM_022717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022717.1 /DEF=Homo sapiens U1-snRNP binding protein homolog (70kD) (U1SNRNPBP), transcript variant 2, mRNA. /FEA=mRNA /GEN=U1SNRNPBP /PROD=U1-snRNP binding protein homolog (70kD), isoforma /DB_XREF=gi:13027641 /UG=Hs.93502 U1-snRNP binding protein homolog (70kD) /FL=gb:U44799.1 gb:NM_022717.1 NM_022717 small nuclear ribonucleoprotein 35kDa (U11/U12) SNRNP35 11066 NM_007020 /// NM_022717 /// NM_180699 /// NM_180703 /// NR_104103 /// XM_005253545 /// XM_006719204 0003382 // epithelial cell morphogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred by curator /// 0015031 // protein transport // inferred from electronic annotation /// 1901214 // regulation of neuron death // inferred from electronic annotation /// 1901214 // regulation of neuron death // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 205301_s_at NM_016820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016820.1 /DEF=Homo sapiens 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1c, mRNA. /FEA=mRNA /GEN=OGG1 /PROD=8-oxoguanine DNA glycosylase, isoform 1c /DB_XREF=gi:8670531 /UG=Hs.96398 8-oxoguanine DNA glycosylase /FL=gb:U96710.1 gb:AF026691.1 gb:NM_016820.1 NM_016820 8-oxoguanine DNA glycosylase OGG1 4968 NM_002542 /// NM_016819 /// NM_016820 /// NM_016821 /// NM_016826 /// NM_016827 /// NM_016828 /// NM_016829 /// XM_005265185 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from direct assay /// 0045007 // depurination // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051835 // positive regulation of synapse structural plasticity // inferred from mutant phenotype /// 0060999 // positive regulation of dendritic spine development // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008534 // oxidized purine nucleobase lesion DNA N-glycosylase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation /// 0034039 // 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity // inferred from electronic annotation 205302_at NM_000596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000596.1 /DEF=Homo sapiens insulin-like growth factor binding protein 1 (IGFBP1), mRNA. /FEA=mRNA /GEN=IGFBP1 /PROD=insulin-like growth factor binding protein 1 /DB_XREF=gi:4504614 /UG=Hs.102122 insulin-like growth factor binding protein 1 /FL=gb:M20841.1 gb:M31145.1 gb:NM_000596.1 NM_000596 insulin-like growth factor binding protein 1 IGFBP1 3484 NM_000596 /// NM_001013029 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 205303_at BF514158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF514158 /FEA=EST /DB_XREF=gi:11599337 /DB_XREF=est:UI-H-BW1-anc-e-06-0-UI.s1 /CLONE=IMAGE:3072082 /UG=Hs.102308 potassium inwardly-rectifying channel, subfamily J, member 8 /FL=gb:D50312.1 gb:BC000544.1 gb:NM_004982.1 BF514158 potassium inwardly-rectifying channel, subfamily J, member 8 KCNJ8 3764 NM_004982 /// XM_005253358 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0008282 // ATP-sensitive potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015272 // ATP-activated inward rectifier potassium channel activity // inferred from electronic annotation /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation 205304_s_at NM_004982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004982.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8), mRNA. /FEA=mRNA /GEN=KCNJ8 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 8 /DB_XREF=gi:4826801 /UG=Hs.102308 potassium inwardly-rectifying channel, subfamily J, member 8 /FL=gb:D50312.1 gb:BC000544.1 gb:NM_004982.1 NM_004982 potassium inwardly-rectifying channel, subfamily J, member 8 KCNJ8 3764 NM_004982 /// XM_005253358 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0008282 // ATP-sensitive potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015272 // ATP-activated inward rectifier potassium channel activity // inferred from electronic annotation /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation 205305_at NM_004467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004467.1 /DEF=Homo sapiens fibrinogen-like 1 (FGL1), mRNA. /FEA=mRNA /GEN=FGL1 /PROD=fibrinogen-like 1 precursor /DB_XREF=gi:4758371 /UG=Hs.107 fibrinogen-like 1 /FL=gb:D14446.1 gb:NM_004467.1 NM_004467 fibrinogen-like 1 FGL1 2267 NM_004467 /// NM_147203 /// NM_201552 /// NM_201553 /// XM_005273450 0035634 // response to stilbenoid // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 205306_x_at AI074145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI074145 /FEA=EST /DB_XREF=gi:3400789 /DB_XREF=est:ov13a06.x1 /CLONE=IMAGE:1637170 /UG=Hs.107318 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) /FL=gb:AF056032.1 gb:NM_003679.1 AI074145 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) KMO 8564 NM_003679 /// XM_005273337 /// XM_005273338 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from direct assay /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070189 // kynurenine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004502 // kynurenine 3-monooxygenase activity // inferred from direct assay /// 0016174 // NAD(P)H oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 205307_s_at NM_003679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003679.1 /DEF=Homo sapiens kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), mRNA. /FEA=mRNA /GEN=KMO /PROD=kynurenine 3-monooxygenase (kynurenine3-hydroxylase) /DB_XREF=gi:4504890 /UG=Hs.107318 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) /FL=gb:AF056032.1 gb:NM_003679.1 NM_003679 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) KMO 8564 NM_003679 /// XM_005273337 /// XM_005273338 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from direct assay /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070189 // kynurenine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004502 // kynurenine 3-monooxygenase activity // inferred from direct assay /// 0016174 // NAD(P)H oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 205308_at NM_016010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016010.1 /DEF=Homo sapiens CGI-62 protein (LOC51101), mRNA. /FEA=mRNA /GEN=LOC51101 /PROD=CGI-62 protein /DB_XREF=gi:7705774 /UG=Hs.118821 CGI-62 protein /FL=gb:AF151820.1 gb:NM_016010.1 NM_016010 zinc finger, C2HC-type containing 1A ZC2HC1A 51101 NM_016010 /// XM_005251256 /// XM_006716454 0046872 // metal ion binding // inferred from electronic annotation 205309_at NM_014474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014474.1 /DEF=Homo sapiens acid sphingomyelinase-like phosphodiesterase (ASML3B), mRNA. /FEA=mRNA /GEN=ASML3B /PROD=acid sphingomyelinase-like phosphodiesterase /DB_XREF=gi:7656907 /UG=Hs.123659 acid sphingomyelinase-like phosphodiesterase /FL=gb:NM_014474.1 NM_014474 sphingomyelin phosphodiesterase, acid-like 3B SMPDL3B 27293 NM_001009568 /// NM_014474 0006685 // sphingomyelin catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 205310_at NM_012066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012066.1 /DEF=Homo sapiens hypothetical protein (20D7-FC4), mRNA. /FEA=mRNA /GEN=20D7-FC4 /PROD=hypothetical protein /DB_XREF=gi:6912227 /UG=Hs.128702 hypothetical protein /FL=gb:NM_012066.1 NM_012066 F-box protein 46 FBXO46 23403 NM_001080469 0005515 // protein binding // inferred from physical interaction 205311_at NM_000790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000790.1 /DEF=Homo sapiens dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), mRNA. /FEA=mRNA /GEN=DDC /PROD=dopa decarboxylase (aromatic L-amino aciddecarboxylase) /DB_XREF=gi:4503280 /UG=Hs.150403 dopa decarboxylase (aromatic L-amino acid decarboxylase) /FL=gb:BC000485.1 gb:M76180.1 gb:M88700.1 gb:NM_000790.1 NM_000790 dopa decarboxylase (aromatic L-amino acid decarboxylase) DDC 1644 NM_000790 /// NM_001082971 /// NM_001242886 /// NM_001242887 /// NM_001242888 /// NM_001242889 /// NM_001242890 /// XM_005271745 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015842 // synaptic vesicle amine transport // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0033076 // isoquinoline alkaloid metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042423 // catecholamine biosynthetic process // traceable author statement /// 0042427 // serotonin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0052314 // phytoalexin metabolic process // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004058 // aromatic-L-amino-acid decarboxylase activity // inferred from direct assay /// 0004058 // aromatic-L-amino-acid decarboxylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 205312_at NM_003120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003120.1 /DEF=Homo sapiens spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1), mRNA. /FEA=mRNA /GEN=SPI1 /PROD=spleen focus forming virus (SFFV) proviralintegration oncogene spi1 /DB_XREF=gi:4507174 /UG=Hs.157441 spleen focus forming virus (SFFV) proviral integration oncogene spi1 /FL=gb:NM_003120.1 NM_003120 Spi-1 proto-oncogene SPI1 6688 NM_001080547 /// NM_003120 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001944 // vasculature development // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // inferred from electronic annotation /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from mutant phenotype /// 0044027 // hypermethylation of CpG island // inferred from direct assay /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation /// 0045646 // regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0090241 // negative regulation of histone H4 acetylation // inferred from mutant phenotype /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001047 // core promoter binding // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity 205313_at NM_000458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000458.1 /DEF=Homo sapiens transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor (TCF2), transcript variant a, mRNA. /FEA=mRNA /GEN=TCF2 /PROD=transcription factor 2, isoform a /DB_XREF=gi:4507396 /UG=Hs.169853 transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor /FL=gb:NM_000458.1 NM_000458 HNF1 homeobox B HNF1B 6928 NM_000458 /// NM_001165923 /// NM_006481 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001714 // endodermal cell fate specification // inferred from electronic annotation /// 0001822 // kidney development // inferred from direct assay /// 0001822 // kidney development // inferred from mutant phenotype /// 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0035565 // regulation of pronephros size // inferred from mutant phenotype /// 0039020 // pronephric nephron tubule development // inferred from genetic interaction /// 0042663 // regulation of endodermal cell fate specification // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048793 // pronephros development // inferred from mutant phenotype /// 0048806 // genitalia development // inferred from mutant phenotype /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060429 // epithelium development // inferred from electronic annotation /// 0060677 // ureteric bud elongation // inferred from electronic annotation /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061017 // hepatoblast differentiation // inferred from electronic annotation /// 0061296 // negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis // inferred from electronic annotation /// 0072095 // regulation of branch elongation involved in ureteric bud branching // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072176 // nephric duct development // inferred from electronic annotation /// 0072177 // mesonephric duct development // inferred from electronic annotation /// 0072179 // nephric duct formation // inferred from electronic annotation /// 0072181 // mesonephric duct formation // inferred from electronic annotation /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205314_x_at U40572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U40572.1 /DEF=Human beta2-syntrophin (SNT B2) mRNA, complete cds. /FEA=mRNA /GEN=SNT B2 /PROD=beta2-syntrophin /DB_XREF=gi:1145729 /UG=Hs.172278 syntrophin, beta 2 (dystrophin-associated protein A1, 59kD, basic component 2) /FL=gb:U40572.1 gb:NM_006750.1 U40572 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) SNTB2 6645 NM_006750 /// NM_130845 /// XM_005256120 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205315_s_at NM_006750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006750.1 /DEF=Homo sapiens syntrophin, beta 2 (dystrophin-associated protein A1, 59kD, basic component 2) (SNTB2), mRNA. /FEA=mRNA /GEN=SNTB2 /PROD=syntrophin, beta 2 (dystrophin-associatedprotein A1, 59kD, basic component 2) /DB_XREF=gi:5803176 /UG=Hs.172278 syntrophin, beta 2 (dystrophin-associated protein A1, 59kD, basic component 2) /FL=gb:U40572.1 gb:NM_006750.1 NM_006750 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) SNTB2 6645 NM_006750 /// NM_130845 /// XM_005256120 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205316_at BF223679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223679 /FEA=EST /DB_XREF=gi:11130857 /DB_XREF=est:7q78g05.x1 /CLONE=IMAGE:3704625 /UG=Hs.182575 solute carrier family 15 (H+peptide transporter), member 2 /FL=gb:NM_021082.1 BF223679 solute carrier family 15 (oligopeptide transporter), member 2 SLC15A2 6565 NM_001145998 /// NM_021082 /// XM_005247722 /// XM_005247723 /// XM_006713736 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006857 // oligopeptide transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015893 // drug transport // non-traceable author statement /// 0015992 // proton transport // traceable author statement /// 0042891 // antibiotic transport // inferred from electronic annotation /// 0042938 // dipeptide transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015198 // oligopeptide transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015333 // peptide:proton symporter activity // traceable author statement /// 0015334 // high affinity oligopeptide transporter activity // inferred from electronic annotation /// 0042895 // antibiotic transporter activity // inferred from electronic annotation /// 0042936 // dipeptide transporter activity // inferred from electronic annotation 205317_s_at NM_021082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021082.1 /DEF=Homo sapiens solute carrier family 15 (H+peptide transporter), member 2 (SLC15A2), mRNA. /FEA=mRNA /GEN=SLC15A2 /PROD=solute carrier family 15 (H+peptidetransporter), member 2 /DB_XREF=gi:10835270 /UG=Hs.182575 solute carrier family 15 (H+peptide transporter), member 2 /FL=gb:NM_021082.1 NM_021082 solute carrier family 15 (oligopeptide transporter), member 2 SLC15A2 6565 NM_001145998 /// NM_021082 /// XM_005247722 /// XM_005247723 /// XM_006713736 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006857 // oligopeptide transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015893 // drug transport // non-traceable author statement /// 0015992 // proton transport // traceable author statement /// 0042891 // antibiotic transport // inferred from electronic annotation /// 0042938 // dipeptide transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015198 // oligopeptide transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015333 // peptide:proton symporter activity // traceable author statement /// 0015334 // high affinity oligopeptide transporter activity // inferred from electronic annotation /// 0042895 // antibiotic transporter activity // inferred from electronic annotation /// 0042936 // dipeptide transporter activity // inferred from electronic annotation 205318_at NM_004984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004984.1 /DEF=Homo sapiens kinesin family member 5A (KIF5A), mRNA. /FEA=mRNA /GEN=KIF5A /PROD=kinesin family member 5A /DB_XREF=gi:4826807 /UG=Hs.192760 kinesin family member 5A /FL=gb:NM_004984.1 gb:U06698.1 NM_004984 kinesin family member 5A KIF5A 3798 NM_004984 0007018 // microtubule-based movement // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 205319_at NM_005672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005672.1 /DEF=Homo sapiens prostate stem cell antigen (PSCA), mRNA. /FEA=mRNA /GEN=PSCA /PROD=prostate stem cell antigen /DB_XREF=gi:5031994 /UG=Hs.20166 prostate stem cell antigen /FL=gb:AF043498.1 gb:NM_005672.1 NM_005672 prostate stem cell antigen PSCA 8000 NM_005672 /// NR_033343 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 205320_at NM_005883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005883.1 /DEF=Homo sapiens adenomatous polyposis coli like (APCL), mRNA. /FEA=mRNA /GEN=APCL /PROD=adenomatous polyposis coli like /DB_XREF=gi:5031586 /UG=Hs.20912 adenomatous polyposis coli like /FL=gb:AB012162.1 gb:NM_005883.1 NM_005883 adenomatosis polyposis coli 2 APC2 10297 NM_005883 /// XM_005259475 /// XM_006722607 /// XM_006722608 /// XM_006722609 /// XM_006722610 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0035414 // negative regulation of catenin import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from electronic annotation 205321_at NM_001415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001415.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2, subunit 3 (gamma, 52kD) (EIF2S3), mRNA. /FEA=mRNA /GEN=EIF2S3 /PROD=eukaryotic translation initiation factor 2,subunit 3 (gamma, 52kD) /DB_XREF=gi:4503506 /UG=Hs.211539 eukaryotic translation initiation factor 2, subunit 3 (gamma, 52kD) /FL=gb:L19161.1 gb:NM_001415.1 NM_001415 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa EIF2S3 1968 NM_001415 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay 205322_s_at AW182367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW182367 /FEA=EST /DB_XREF=gi:6450827 /DB_XREF=est:xj41g06.x1 /CLONE=IMAGE:2659834 /UG=Hs.211581 metal-regulatory transcription factor 1 /FL=gb:NM_005955.1 AW182367 metal-regulatory transcription factor 1 MTF1 4520 NM_005955 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0010038 // response to metal ion // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046686 // response to cadmium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205323_s_at NM_005955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005955.1 /DEF=Homo sapiens metal-regulatory transcription factor 1 (MTF1), mRNA. /FEA=mRNA /GEN=MTF1 /PROD=metal-regulatory transcription factor 1 /DB_XREF=gi:5174588 /UG=Hs.211581 metal-regulatory transcription factor 1 /FL=gb:NM_005955.1 NM_005955 metal-regulatory transcription factor 1 MTF1 4520 NM_005955 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0010038 // response to metal ion // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046686 // response to cadmium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205324_s_at NM_012280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012280.1 /DEF=Homo sapiens homolog of yeast SPB1 (JM23), mRNA. /FEA=mRNA /GEN=JM23 /PROD=homolog of yeast SPB1 /DB_XREF=gi:7110660 /UG=Hs.23170 homolog of yeast SPB1 /FL=gb:NM_012280.1 NM_012280 FtsJ RNA methyltransferase homolog 1 (E. coli) FTSJ1 24140 NM_001282157 /// NM_012280 /// NM_177439 /// XM_005272595 /// XR_246715 /// XR_246716 /// XR_430505 0001510 // RNA methylation // inferred from electronic annotation /// 0002128 // tRNA nucleoside ribose methylation // inferred from electronic annotation /// 0002181 // cytoplasmic translation // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008175 // tRNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205325_at NM_014759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014759.1 /DEF=Homo sapiens KIAA0273 gene product (KIAA0273), mRNA. /FEA=mRNA /GEN=KIAA0273 /PROD=KIAA0273 gene product /DB_XREF=gi:7662031 /UG=Hs.239500 KIAA0273 gene product /FL=gb:D87463.1 gb:NM_014759.1 NM_014759 phytanoyl-CoA 2-hydroxylase interacting protein PHYHIP 9796 NM_001099335 /// NM_014759 /// XM_006716416 /// XR_247134 0005515 // protein binding // inferred from electronic annotation 205326_at NM_005856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005856.1 /DEF=Homo sapiens receptor (calcitonin) activity modifying protein 3 (RAMP3), mRNA. /FEA=mRNA /GEN=RAMP3 /PROD=receptor (calcitonin) activity modifying protein3 precursor /DB_XREF=gi:5032022 /UG=Hs.25691 receptor (calcitonin) activity modifying protein 3 /FL=gb:NM_005856.1 NM_005856 receptor (G protein-coupled) activity modifying protein 3 RAMP3 10268 NM_005856 /// XM_006715631 /// XM_006715632 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0086103 // G-protein coupled receptor signaling pathway involved in heart process // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay /// 0015026 // coreceptor activity // inferred from electronic annotation 205327_s_at NM_001616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001616.2 /DEF=Homo sapiens activin A receptor, type II (ACVR2), mRNA. /FEA=mRNA /GEN=ACVR2 /PROD=activin A type II receptor precursor /DB_XREF=gi:10862696 /UG=Hs.26014 activin A receptor, type II /FL=gb:NM_001616.2 gb:D31770.1 NM_001616 activin A receptor, type IIA ACVR2A 92 NM_001278579 /// NM_001278580 /// NM_001616 /// XM_005263843 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0030510 // regulation of BMP signaling pathway // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050999 // regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034673 // inhibin-betaglycan-ActRII complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015026 // coreceptor activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0034711 // inhibin binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from physical interaction 205328_at NM_006984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006984.1 /DEF=Homo sapiens claudin 10 (CLDN10), mRNA. /FEA=mRNA /GEN=CLDN10 /PROD=claudin 10 /DB_XREF=gi:5921464 /UG=Hs.26126 claudin 10 /FL=gb:U89916.1 gb:NM_006984.1 NM_006984 claudin 10 CLDN10 9071 NM_001160100 /// NM_006984 /// NM_182848 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 205329_s_at NM_003794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003794.1 /DEF=Homo sapiens sorting nexin 4 (SNX4), mRNA. /FEA=mRNA /GEN=SNX4 /PROD=sorting nexin 4 /DB_XREF=gi:4507144 /UG=Hs.267812 sorting nexin 4 /FL=gb:AF130078.1 gb:AF065485.1 gb:NM_003794.1 NM_003794 sorting nexin 4 SNX4 8723 NM_003794 /// NR_073435 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0032456 // endocytic recycling // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from mutant phenotype 205330_at NM_002430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002430.1 /DEF=Homo sapiens meningioma (disrupted in balanced translocation) 1 (MN1), mRNA. /FEA=mRNA /GEN=MN1 /PROD=meningioma 1 /DB_XREF=gi:4505222 /UG=Hs.268515 meningioma (disrupted in balanced translocation) 1 /FL=gb:NM_002430.1 NM_002430 meningioma (disrupted in balanced translocation) 1 MN1 4330 NM_002430 0001957 // intramembranous ossification // inferred from electronic annotation 205331_s_at NM_016606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016606.1 /DEF=Homo sapiens SGC32445 protein (LOC51308), mRNA. /FEA=mRNA /GEN=LOC51308 /PROD=SGC32445 protein /DB_XREF=gi:7706140 /UG=Hs.28088 SGC32445 protein /FL=gb:AF251041.1 gb:NM_016606.1 NM_016606 receptor accessory protein 2 REEP2 51308 NM_001271803 /// NM_016606 /// NR_073448 /// NR_073449 0008219 // cell death // inferred from electronic annotation /// 0032596 // protein transport into membrane raft // inferred from electronic annotation /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0031883 // taste receptor binding // inferred from electronic annotation 205332_at AF121951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF121951.1 /DEF=Homo sapiens CAAX prenyl protein protease RCE1 (RCE1) mRNA, complete cds. /FEA=mRNA /GEN=RCE1 /PROD=CAAX prenyl protein protease RCE1 /DB_XREF=gi:4558496 /UG=Hs.288626 RCE1, prenyl protein protease (yeast homolog B) /FL=gb:AF121951.1 gb:NM_005133.1 AF121951 Ras converting CAAX endopeptidase 1 RCE1 9986 NM_001032279 /// NM_005133 0006508 // proteolysis // traceable author statement /// 0071586 // CAAX-box protein processing // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205333_s_at NM_005133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005133.1 /DEF=Homo sapiens RCE1, prenyl protein protease (yeast homolog B) (RCE1B), mRNA. /FEA=mRNA /GEN=RCE1B /PROD=prenyl protein protease RCE1B /DB_XREF=gi:4826975 /UG=Hs.288626 RCE1, prenyl protein protease (yeast homolog B) /FL=gb:AF121951.1 gb:NM_005133.1 NM_005133 Ras converting CAAX endopeptidase 1 RCE1 9986 NM_001032279 /// NM_005133 0006508 // proteolysis // traceable author statement /// 0071586 // CAAX-box protein processing // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205334_at NM_006271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006271.1 /DEF=Homo sapiens S100 calcium-binding protein A1 (S100A1), mRNA. /FEA=mRNA /GEN=S100A1 /PROD=S100 calcium-binding protein A1 /DB_XREF=gi:5454031 /UG=Hs.292707 S100 calcium-binding protein A1 /FL=gb:NM_006271.1 NM_006271 S100 calcium binding protein A1 S100A1 6271 NM_006271 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008016 // regulation of heart contraction // non-traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0035556 // intracellular signal transduction // non-traceable author statement /// 1901387 // positive regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 205335_s_at NM_003135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003135.1 /DEF=Homo sapiens signal recognition particle 19kD (SRP19), mRNA. /FEA=mRNA /GEN=SRP19 /PROD=signal recognition particle 19kD /DB_XREF=gi:4507212 /UG=Hs.2943 signal recognition particle 19kD /FL=gb:NM_003135.1 NM_003135 signal recognition particle 19kDa SRP19 6728 NM_001204193 /// NM_001204194 /// NM_001204196 /// NM_001204199 /// NM_003135 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205336_at NM_002854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002854.1 /DEF=Homo sapiens parvalbumin (PVALB), mRNA. /FEA=mRNA /GEN=PVALB /PROD=parvalbumin /DB_XREF=gi:4506334 /UG=Hs.295449 parvalbumin /FL=gb:NM_002854.1 NM_002854 parvalbumin PVALB 5816 NM_002854 /// XM_006724285 /// XM_006725404 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205337_at AL139318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139318 /DEF=Human DNA sequence from clone RP11-124B17 on chromosome 13. Contains the DCT gene for dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), the 3 end of the gene for DTDP-D-glucose 4,6-dehydratase, ESTs, STSs, GSSs and ... /FEA=mRNA_1 /DB_XREF=gi:9800060 /UG=Hs.301865 dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) /FL=gb:L18967.1 gb:D17547.1 gb:NM_001922.2 AL139318 dopachrome tautomerase DCT 1638 NM_001129889 /// NM_001922 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006583 // melanin biosynthetic process from tyrosine // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from sequence or structural similarity 0004167 // dopachrome isomerase activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205338_s_at NM_001922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001922.2 /DEF=Homo sapiens dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) (DCT), mRNA. /FEA=mRNA /GEN=DCT /PROD=dopachrome tautomerase (dopachromedelta-isomerase, tyrosine-related protein 2) /DB_XREF=gi:6041666 /UG=Hs.301865 dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) /FL=gb:L18967.1 gb:D17547.1 gb:NM_001922.2 NM_001922 dopachrome tautomerase DCT 1638 NM_001129889 /// NM_001922 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006583 // melanin biosynthetic process from tyrosine // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from sequence or structural similarity 0004167 // dopachrome isomerase activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205339_at NM_003035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003035.1 /DEF=Homo sapiens TAL1 (SCL) interrupting locus (SIL), mRNA. /FEA=mRNA /GEN=SIL /PROD=TAL1 (SCL) interrupting locus /DB_XREF=gi:4506958 /UG=Hs.323032 TAL1 (SCL) interrupting locus /FL=gb:M74558.1 gb:NM_003035.1 NM_003035 SCL/TAL1 interrupting locus STIL 6491 NM_001048166 /// NM_001282936 /// NM_001282937 /// NM_001282938 /// NM_001282939 /// NM_003035 /// XM_006710834 /// XM_006710835 0000578 // embryonic axis specification // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0021915 // neural tube development // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0030903 // notochord development // inferred from sequence or structural similarity /// 0033504 // floor plate development // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205340_at NM_014797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014797.1 /DEF=Homo sapiens KIAA0441 gene product (KIAA0441), mRNA. /FEA=mRNA /GEN=KIAA0441 /PROD=KIAA0441 gene product /DB_XREF=gi:7662127 /UG=Hs.32511 KIAA0441 gene product /FL=gb:AB007901.1 gb:NM_014797.1 NM_014797 zinc finger and BTB domain containing 24 ZBTB24 9841 NM_001164313 /// NM_014797 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205341_at NM_014601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014601.1 /DEF=Homo sapiens EH-domain containing 2 (EHD2), mRNA. /FEA=mRNA /GEN=EHD2 /PROD=EH-domain containing 2 /DB_XREF=gi:7657053 /UG=Hs.325650 EH-domain containing 2 /FL=gb:AF181263.1 gb:NM_014601.1 NM_014601 EH-domain containing 2 EHD2 30846 NM_014601 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205342_s_at AF026303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026303.1 /DEF=Homo sapiens sulfotransferase mRNA, complete cds. /FEA=mRNA /PROD=sulfotransferase /DB_XREF=gi:2828823 /UG=Hs.38084 sulfotransferase family, cytosolic, 1C, member 1 /FL=gb:BC005353.1 gb:U66036.1 gb:AF026303.1 gb:AB008164.1 gb:NM_001056.1 gb:AF186251.1 gb:AF186252.1 gb:AF186253.1 AF026303 sulfotransferase family, cytosolic, 1C, member 2 SULT1C2 6819 NM_001056 /// NM_176825 /// XM_005264013 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009308 // amine metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 205343_at NM_001056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001056.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 1C, member 1 (SULT1C1), mRNA. /FEA=mRNA /GEN=SULT1C1 /PROD=sulfotransferase family, cytosolic, 1C, member1 /DB_XREF=gi:4507304 /UG=Hs.38084 sulfotransferase family, cytosolic, 1C, member 1 /FL=gb:BC005353.1 gb:U66036.1 gb:AF026303.1 gb:AB008164.1 gb:NM_001056.1 gb:AF186251.1 gb:AF186252.1 gb:AF186253.1 NM_001056 sulfotransferase family, cytosolic, 1C, member 2 SULT1C2 6819 NM_001056 /// NM_176825 /// XM_005264013 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009308 // amine metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 205344_at NM_006574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006574.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan 5 (neuroglycan C) (CSPG5), mRNA. /FEA=mRNA /GEN=CSPG5 /PROD=chondroitin sulfate proteoglycan 5 (neuroglycanC) /DB_XREF=gi:5729787 /UG=Hs.45127 chondroitin sulfate proteoglycan 5 (neuroglycan C) /FL=gb:AF059274.1 gb:NM_006574.1 NM_006574 chondroitin sulfate proteoglycan 5 (neuroglycan C) CSPG5 10675 NM_001206942 /// NM_001206943 /// NM_001206944 /// NM_001206945 /// NM_006574 0005975 // carbohydrate metabolic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0031103 // axon regeneration // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement 205345_at NM_000465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000465.1 /DEF=Homo sapiens BRCA1 associated RING domain 1 (BARD1), mRNA. /FEA=mRNA /GEN=BARD1 /PROD=BRCA1 associated RING domain 1 /DB_XREF=gi:4557348 /UG=Hs.54089 BRCA1 associated RING domain 1 /FL=gb:U76638.1 gb:NM_000465.1 NM_000465 BRCA1 associated RING domain 1 BARD1 580 NM_000465 /// NM_001282543 /// NM_001282545 /// NM_001282548 /// NM_001282549 /// NR_104212 /// NR_104215 /// NR_104216 0001894 // tissue homeostasis // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement /// 0007050 // cell cycle arrest // non-traceable author statement /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031441 // negative regulation of mRNA 3'-end processing // non-traceable author statement /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // non-traceable author statement /// 0046826 // negative regulation of protein export from nucleus // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031436 // BRCA1-BARD1 complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 205346_at NM_006927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006927.1 /DEF=Homo sapiens sialyltransferase 4B (beta-galactosidase alpha-2,3-sialytransferase) (SIAT4B), mRNA. /FEA=mRNA /GEN=SIAT4B /PROD=sialyltransferase 4B (beta-galactosidasealpha-2,3-sialytransferase) /DB_XREF=gi:5902081 /UG=Hs.54432 sialyltransferase 4B (beta-galactosidase alpha-2,3-sialytransferase) /FL=gb:U63090.1 gb:NM_006927.1 NM_006927 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 ST3GAL2 6483 NM_006927 0005975 // carbohydrate metabolic process // traceable author statement /// 0006040 // amino sugar metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 205347_s_at NM_021992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021992.1 /DEF=Homo sapiens thymosin, beta, identified in neuroblastoma cells (TMSNB), mRNA. /FEA=mRNA /GEN=TMSNB /PROD=thymosin, beta, identified in neuroblastomacells /DB_XREF=gi:11496272 /UG=Hs.56145 thymosin, beta, identified in neuroblastoma cells /FL=gb:NM_021992.1 gb:BC000183.1 gb:D82345.1 NM_021992 thymosin beta 15a /// thymosin beta 15B TMSB15A /// TMSB15B 11013 /// 286527 NM_021992 /// NM_194324 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042989 // sequestering of actin monomers // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 205348_s_at NM_004411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004411.1 /DEF=Homo sapiens dynein, cytoplasmic, intermediate polypeptide 1 (DNCI1), mRNA. /FEA=mRNA /GEN=DNCI1 /PROD=dynein, cytoplasmic, intermediate polypeptide 1 /DB_XREF=gi:4758177 /UG=Hs.65248 dynein, cytoplasmic, intermediate polypeptide 1 /FL=gb:AF063228.1 gb:NM_004411.1 NM_004411 dynein, cytoplasmic 1, intermediate chain 1 DYNC1I1 1780 NM_001135556 /// NM_001135557 /// NM_001278421 /// NM_001278422 /// NM_004411 /// XM_006715870 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from direct assay 205349_at NM_002068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002068.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha 15 (Gq class) (GNA15), mRNA. /FEA=mRNA /GEN=GNA15 /PROD=guanine nucleotide binding protein (G protein),alpha 15 (Gq class) /DB_XREF=gi:4504038 /UG=Hs.73797 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) /FL=gb:M63904.1 gb:NM_002068.1 NM_002068 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) GNA15 2769 NM_002068 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0007207 // phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from genetic interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205350_at NM_004378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004378.1 /DEF=Homo sapiens cellular retinoic acid-binding protein 1 (CRABP1), mRNA. /FEA=mRNA /GEN=CRABP1 /PROD=cellular retinoic acid-binding protein 1 /DB_XREF=gi:4758051 /UG=Hs.7678 cellular retinoic acid-binding protein 1 /FL=gb:NM_004378.1 NM_004378 cellular retinoic acid binding protein 1 CRABP1 1381 NM_004378 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 205351_at NM_000821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000821.1 /DEF=Homo sapiens gamma-glutamyl carboxylase (GGCX), mRNA. /FEA=mRNA /GEN=GGCX /PROD=gamma-glutamyl carboxylase /DB_XREF=gi:4503984 /UG=Hs.77719 gamma-glutamyl carboxylase /FL=gb:L17128.1 gb:M81592.1 gb:NM_000821.1 NM_000821 gamma-glutamyl carboxylase GGCX 2677 NM_000821 /// NM_001142269 /// XM_005264259 0006464 // cellular protein modification process // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008488 // gamma-glutamyl carboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 205352_at NM_005025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005025.1 /DEF=Homo sapiens protease inhibitor 12 (neuroserpin) (SERPINI1), mRNA. /FEA=mRNA /GEN=SERPINI1 /PROD=protease inhibitor 12 (neuroserpin) /DB_XREF=gi:4826903 /UG=Hs.78589 serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1 /FL=gb:NM_005025.1 NM_005025 serpin peptidase inhibitor, clade I (neuroserpin), member 1 SERPINI1 5274 NM_001122752 /// NM_005025 /// XM_006713657 0007417 // central nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205353_s_at NM_002567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002567.1 /DEF=Homo sapiens prostatic binding protein (PBP), mRNA. /FEA=mRNA /GEN=PBP /PROD=prostatic binding protein /DB_XREF=gi:4505620 /UG=Hs.80423 prostatic binding protein /FL=gb:D16111.1 gb:NM_002567.1 NM_002567 phosphatidylethanolamine binding protein 1 PEBP1 5037 NM_002567 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205354_at NM_000156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000156.3 /DEF=Homo sapiens guanidinoacetate N-methyltransferase (GAMT), mRNA. /FEA=mRNA /GEN=GAMT /PROD=guanidinoacetate N-methyltransferase /DB_XREF=gi:7549759 /UG=Hs.81131 guanidinoacetate N-methyltransferase /FL=gb:NM_000156.3 NM_000156 guanidinoacetate N-methyltransferase GAMT 2593 NM_000156 /// NM_138924 0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0030731 // guanidinoacetate N-methyltransferase activity // inferred from mutant phenotype 205355_at NM_001609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001609.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, shortbranched chain (ACADSB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADSB /PROD=acyl-Coenzyme A dehydrogenase, shortbranchedchain precursor /DB_XREF=gi:4501858 /UG=Hs.81934 acyl-Coenzyme A dehydrogenase, shortbranched chain /FL=gb:NM_001609.1 gb:U12778.1 NM_001609 acyl-CoA dehydrogenase, short/branched chain ACADSB 36 NM_001609 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 205356_at NM_003940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003940.1 /DEF=Homo sapiens ubiquitin specific protease 13 (isopeptidase T-3) (USP13), mRNA. /FEA=mRNA /GEN=USP13 /PROD=ubiquitin specific protease 13 (isopeptidaseT-3) /DB_XREF=gi:4507848 /UG=Hs.85482 ubiquitin specific protease 13 (isopeptidase T-3) /FL=gb:U75362.1 gb:NM_003940.1 NM_003940 ubiquitin specific peptidase 13 (isopeptidase T-3) USP13 8975 NM_003940 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010506 // regulation of autophagy // inferred from direct assay /// 0030318 // melanocyte differentiation // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205357_s_at NM_000685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000685.2 /DEF=Homo sapiens angiotensin receptor 1 (AGTR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=AGTR1 /PROD=angiotensin receptor 1 /DB_XREF=gi:6715581 /UG=Hs.89472 angiotensin receptor 1 /FL=gb:M93394.1 gb:NM_000685.2 NM_000685 angiotensin II receptor, type 1 AGTR1 185 NM_000685 /// NM_004835 /// NM_009585 /// NM_031850 /// NM_032049 0001558 // regulation of cell growth // non-traceable author statement /// 0001822 // kidney development // inferred from mutant phenotype /// 0002018 // renin-angiotensin regulation of aldosterone production // non-traceable author statement /// 0002034 // regulation of blood vessel size by renin-angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010873 // positive regulation of cholesterol esterification // inferred from mutant phenotype /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0019229 // regulation of vasoconstriction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032430 // positive regulation of phospholipase A2 activity // inferred from mutant phenotype /// 0033864 // positive regulation of NAD(P)H oxidase activity // traceable author statement /// 0034374 // low-density lipoprotein particle remodeling // non-traceable author statement /// 0035813 // regulation of renal sodium excretion // non-traceable author statement /// 0038166 // angiotensin-activated signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042312 // regulation of vasodilation // inferred by curator /// 0050727 // regulation of inflammatory response // inferred by curator /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from physical interaction /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001596 // angiotensin type I receptor activity // inferred from direct assay /// 0001596 // angiotensin type I receptor activity // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010698 // acetyltransferase activator activity // inferred from mutant phenotype /// 0031711 // bradykinin receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 205358_at NM_000826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000826.1 /DEF=Homo sapiens glutamate receptor, ionotropic, AMPA 2 (GRIA2), mRNA. /FEA=mRNA /GEN=GRIA2 /PROD=glutamate receptor precursor, flip isoform /DB_XREF=gi:4758479 /UG=Hs.89582 glutamate receptor, ionotropic, AMPA 2 /FL=gb:NM_000826.1 gb:L20814.1 NM_000826 glutamate receptor, ionotropic, AMPA 2 GRIA2 2891 NM_000826 /// NM_001083619 /// NM_001083620 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from direct assay /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // not recorded /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // traceable author statement /// 0015277 // kainate selective glutamate receptor activity // inferred from sequence or structural similarity 205359_at NM_004274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004274.2 /DEF=Homo sapiens A kinase (PRKA) anchor protein 6 (AKAP6), mRNA. /FEA=mRNA /GEN=AKAP6 /PROD=A kinase (PRKA) anchor protein 6 /DB_XREF=gi:5729892 /UG=Hs.89666 A kinase (PRKA) anchor protein 6 /FL=gb:U17195.2 gb:NM_004274.2 NM_004274 A kinase (PRKA) anchor protein 6 AKAP6 9472 NM_004274 /// XM_005268219 0001508 // action potential // inferred by curator /// 0006605 // protein targeting // non-traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0032514 // positive regulation of protein phosphatase type 2B activity // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from sequence or structural similarity /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061051 // positive regulation of cell growth involved in cardiac muscle cell development // inferred from sequence or structural similarity /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902261 // positive regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0034237 // protein kinase A regulatory subunit binding // inferred from sequence or structural similarity /// 0043495 // protein anchor // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0051018 // protein kinase A binding // non-traceable author statement /// 0051018 // protein kinase A binding // traceable author statement 205360_at AI718295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI718295 /FEA=EST /DB_XREF=gi:5035551 /DB_XREF=est:as51g04.x1 /CLONE=IMAGE:2320758 /UG=Hs.91161 prefoldin 4 /FL=gb:NM_002623.2 gb:U41816.1 AI718295 prefoldin subunit 4 PFDN4 5203 NM_002623 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0016272 // prefoldin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 205361_s_at AI718295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI718295 /FEA=EST /DB_XREF=gi:5035551 /DB_XREF=est:as51g04.x1 /CLONE=IMAGE:2320758 /UG=Hs.91161 prefoldin 4 /FL=gb:NM_002623.2 gb:U41816.1 AI718295 prefoldin subunit 4 PFDN4 5203 NM_002623 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0016272 // prefoldin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 205362_s_at NM_002623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002623.2 /DEF=Homo sapiens prefoldin 4 (PFDN4), mRNA. /FEA=mRNA /GEN=PFDN4 /PROD=prefoldin 4 /DB_XREF=gi:12408676 /UG=Hs.91161 prefoldin 4 /FL=gb:NM_002623.2 gb:U41816.1 NM_002623 prefoldin subunit 4 PFDN4 5203 NM_002623 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0016272 // prefoldin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 205363_at NM_003986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003986.1 /DEF=Homo sapiens butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (BBOX1), mRNA. /FEA=mRNA /GEN=BBOX1 /PROD=gamma-butyrobetaine hydroxylase /DB_XREF=gi:4502368 /UG=Hs.9667 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 /FL=gb:AF082868.1 gb:NM_003986.1 NM_003986 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 BBOX1 8424 NM_003986 /// XM_005253159 /// XM_005253160 /// XM_005253161 /// XM_005253163 /// XM_006718344 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from direct assay /// 0045329 // carnitine biosynthetic process // inferred from electronic annotation /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008336 // gamma-butyrobetaine dioxygenase activity // inferred from direct assay /// 0008336 // gamma-butyrobetaine dioxygenase activity // inferred from sequence or structural similarity /// 0008336 // gamma-butyrobetaine dioxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205364_at NM_003500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003500.1 /DEF=Homo sapiens acyl-Coenzyme A oxidase 2, branched chain (ACOX2), mRNA. /FEA=mRNA /GEN=ACOX2 /PROD=acyl-Coenzyme A oxidase 2, branched chain /DB_XREF=gi:4501868 /UG=Hs.9795 acyl-Coenzyme A oxidase 2, branched chain /FL=gb:NM_003500.1 NM_003500 acyl-CoA oxidase 2, branched chain ACOX2 8309 NM_003500 /// XM_005265505 /// XM_005265506 /// XM_006713340 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0016402 // pristanoyl-CoA oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0033791 // 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 205365_at AA527340 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527340 /FEA=EST /DB_XREF=gi:2269409 /DB_XREF=est:ng36d08.s1 /CLONE=IMAGE:936879 /UG=Hs.98428 homeo box B6 /FL=gb:NM_018952.1 AA527340 homeobox B6 HOXB6 3216 NM_018952 /// NM_156036 /// NM_156037 /// XM_005257283 /// XM_005257284 /// XM_005257285 /// XM_006721856 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205366_s_at NM_018952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018952.1 /DEF=Homo sapiens homeo box B6 (HOXB6), mRNA. /FEA=mRNA /GEN=HOXB6 /PROD=homeo box B6 /DB_XREF=gi:9506792 /UG=Hs.98428 homeo box B6 /FL=gb:NM_018952.1 NM_018952 homeobox B6 HOXB6 3216 NM_018952 /// NM_156036 /// NM_156037 /// XM_005257283 /// XM_005257284 /// XM_005257285 /// XM_006721856 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008595 // anterior/posterior axis specification, embryo // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205367_at NM_020979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020979.1 /DEF=Homo sapiens adaptor protein with pleckstrin homology and src homology 2 domains (APS), mRNA. /FEA=mRNA /GEN=APS /PROD=adaptor protein with pleckstrin homology and srchomology 2 domains /DB_XREF=gi:10280625 /UG=Hs.105052 adaptor protein with pleckstrin homology and src homology 2 domains /FL=gb:NM_020979.1 gb:AB000520.1 NM_020979 SH2B adaptor protein 2 SH2B2 10603 NM_020979 /// XM_005276975 /// XM_005276976 /// XM_005276977 /// XM_005276979 0001922 // B-1 B cell homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046425 // regulation of JAK-STAT cascade // inferred from direct assay /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050851 // antigen receptor-mediated signaling pathway // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008269 // JAK pathway signal transduction adaptor activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation 205368_at NM_014690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014690.1 /DEF=Homo sapiens KIAA0773 gene product (KIAA0773), mRNA. /FEA=mRNA /GEN=KIAA0773 /PROD=KIAA0773 gene product /DB_XREF=gi:7662299 /UG=Hs.135343 KIAA0773 gene product /FL=gb:AB018316.1 gb:NM_014690.1 NM_014690 family with sequence similarity 131, member B FAM131B 9715 NM_001031690 /// NM_001278297 /// NM_014690 /// XM_005250071 /// XM_005250073 /// XM_006716186 205369_x_at J03208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03208.1 /DEF=Human branched chain acyltransferase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:179353 /UG=Hs.139410 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) /FL=gb:J03208.1 gb:NM_001918.1 gb:M27093.1 J03208 dihydrolipoamide branched chain transacylase E2 DBT 1629 NM_001918 /// XM_005270545 /// XM_005270546 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0043754 // dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205370_x_at NM_001918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001918.1 /DEF=Homo sapiens dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) (DBT), mRNA. /FEA=mRNA /GEN=DBT /PROD=dihydrolipoamide branched chain transacylase (E2component of branched chain keto acid dehydrogenasecomplex; maple syrup urine disease) /DB_XREF=gi:4503264 /UG=Hs.139410 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) /FL=gb:J03208.1 gb:NM_001918.1 gb:M27093.1 NM_001918 dihydrolipoamide branched chain transacylase E2 DBT 1629 NM_001918 /// XM_005270545 /// XM_005270546 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0043754 // dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205371_s_at M27093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M27093.1 /DEF=Homo sapiens nuclear-encoded mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b) mRNA, complete cds. /FEA=mRNA /GEN=E2B /PROD=dihydrolipoyl transacylase /DB_XREF=gi:736674 /UG=Hs.139410 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) /FL=gb:J03208.1 gb:NM_001918.1 gb:M27093.1 M27093 dihydrolipoamide branched chain transacylase E2 DBT 1629 NM_001918 /// XM_005270545 /// XM_005270546 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0043754 // dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205372_at NM_002655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002655.1 /DEF=Homo sapiens pleiomorphic adenoma gene 1 (PLAG1), mRNA. /FEA=mRNA /GEN=PLAG1 /PROD=pleiomorphic adenoma gene 1 /DB_XREF=gi:4505854 /UG=Hs.14968 pleiomorphic adenoma gene 1 /FL=gb:U65002.1 gb:NM_002655.1 NM_002655 pleiomorphic adenoma gene 1 PLAG1 5324 NM_001114634 /// NM_001114635 /// NM_002655 /// XM_005251260 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205373_at NM_004389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004389.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha 2 (CTNNA2), mRNA. /FEA=mRNA /GEN=CTNNA2 /PROD=catenin (cadherin-associated protein), alpha 2 /DB_XREF=gi:7656998 /UG=Hs.150917 catenin (cadherin-associated protein), alpha 2 /FL=gb:M94151.2 gb:NM_004389.1 NM_004389 catenin (cadherin-associated protein), alpha 2 CTNNA2 1496 NM_001164883 /// NM_001282597 /// NM_001282598 /// NM_001282599 /// NM_001282600 /// NM_004389 /// XM_006711949 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0021942 // radial glia guided migration of Purkinje cell // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051823 // regulation of synapse structural plasticity // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from electronic annotation 205374_at NM_003063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003063.1 /DEF=Homo sapiens sarcolipin (SLN), mRNA. /FEA=mRNA /GEN=SLN /PROD=sarcolipin /DB_XREF=gi:4507062 /UG=Hs.15219 sarcolipin /FL=gb:BC005261.1 gb:U96094.1 gb:NM_003063.1 NM_003063 sarcolipin SLN 6588 NM_003063 0006816 // calcium ion transport // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0043242 // negative regulation of protein complex disassembly // inferred from sequence or structural similarity /// 0051924 // regulation of calcium ion transport // inferred from sequence or structural similarity /// 0070296 // sarcoplasmic reticulum calcium ion transport // inferred from sequence or structural similarity /// 0090281 // negative regulation of calcium ion import // inferred from sequence or structural similarity /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901077 // regulation of relaxation of muscle // inferred from sequence or structural similarity /// 1901877 // negative regulation of calcium ion binding // inferred from sequence or structural similarity /// 1901881 // positive regulation of protein depolymerization // inferred from sequence or structural similarity /// 1901894 // regulation of calcium-transporting ATPase activity // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from sequence or structural similarity 205375_at NM_005586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005586.2 /DEF=Homo sapiens MyoD family inhibitor (MDFI), mRNA. /FEA=mRNA /GEN=MDFI /PROD=MyoD family inhibitor /DB_XREF=gi:13027633 /UG=Hs.153203 MyoD family inhibitor /FL=gb:NM_005586.2 gb:U78313.1 NM_005586 MyoD family inhibitor MDFI 4188 NM_005586 /// XM_005249117 /// XM_005249118 /// XM_005249119 /// XM_005249120 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0009950 // dorsal/ventral axis specification // inferred from sequence or structural similarity /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation 205376_at NM_003866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003866.1 /DEF=Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kD (INPP4B), mRNA. /FEA=mRNA /GEN=INPP4B /PROD=inositol polyphosphate-4-phosphatase, type II,105kD /DB_XREF=gi:4504706 /UG=Hs.153687 inositol polyphosphate-4-phosphatase, type II, 105kD /FL=gb:U96922.1 gb:NM_003866.1 NM_003866 inositol polyphosphate-4-phosphatase, type II, 105kDa INPP4B 8821 NM_001101669 /// NM_003866 /// XM_005263322 /// XM_005263323 /// XM_005263324 /// XM_005263325 /// XM_006714400 /// XM_006714401 /// XM_006714402 /// XM_006714403 /// XM_006714404 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0046850 // regulation of bone remodeling // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016316 // phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034593 // phosphatidylinositol bisphosphate phosphatase activity // inferred from electronic annotation /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from electronic annotation /// 0034597 // phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity // inferred from electronic annotation 205377_s_at AI190022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI190022 /FEA=EST /DB_XREF=gi:3741231 /DB_XREF=est:qd35e12.x1 /CLONE=IMAGE:1731502 /UG=Hs.154495 acetylcholinesterase (YT blood group) /FL=gb:NM_015831.1 AI190022 acetylcholinesterase (Yt blood group) ACHE 43 NM_000665 /// NM_001282449 /// NM_015831 /// XM_005250357 /// XM_005250358 /// XM_006715994 /// XM_006715995 0001507 // acetylcholine catabolic process in synaptic cleft // non-traceable author statement /// 0001919 // regulation of receptor recycling // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from expression pattern /// 0006260 // DNA replication // traceable author statement /// 0006581 // acetylcholine catabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // not recorded /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // not recorded /// 0007416 // synapse assembly // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0019695 // choline metabolic process // not recorded /// 0031623 // receptor internalization // inferred from electronic annotation /// 0032223 // negative regulation of synaptic transmission, cholinergic // inferred by curator /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042982 // amyloid precursor protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045212 // neurotransmitter receptor biosynthetic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // not recorded /// 0050714 // positive regulation of protein secretion // traceable author statement /// 0050770 // regulation of axonogenesis // not recorded /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005605 // basal lamina // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // traceable author statement /// 0003990 // acetylcholinesterase activity // inferred from direct assay /// 0003990 // acetylcholinesterase activity // inferred from mutant phenotype /// 0004104 // cholinesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from direct assay /// 0017171 // serine hydrolase activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred from direct assay /// 0042166 // acetylcholine binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from electronic annotation 205378_s_at NM_015831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015831.1 /DEF=Homo sapiens acetylcholinesterase (YT blood group) (ACHE), transcript variant E4-E5, mRNA. /FEA=mRNA /GEN=ACHE /PROD=acetylcholinesterase PI-linked form precursor /DB_XREF=gi:7710111 /UG=Hs.154495 acetylcholinesterase (YT blood group) /FL=gb:NM_015831.1 NM_015831 acetylcholinesterase (Yt blood group) ACHE 43 NM_000665 /// NM_001282449 /// NM_015831 /// XM_005250357 /// XM_005250358 /// XM_006715994 /// XM_006715995 0001507 // acetylcholine catabolic process in synaptic cleft // non-traceable author statement /// 0001919 // regulation of receptor recycling // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from expression pattern /// 0006260 // DNA replication // traceable author statement /// 0006581 // acetylcholine catabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // not recorded /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // not recorded /// 0007416 // synapse assembly // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0019695 // choline metabolic process // not recorded /// 0031623 // receptor internalization // inferred from electronic annotation /// 0032223 // negative regulation of synaptic transmission, cholinergic // inferred by curator /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042982 // amyloid precursor protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045212 // neurotransmitter receptor biosynthetic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // not recorded /// 0050714 // positive regulation of protein secretion // traceable author statement /// 0050770 // regulation of axonogenesis // not recorded /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005605 // basal lamina // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // traceable author statement /// 0003990 // acetylcholinesterase activity // inferred from direct assay /// 0003990 // acetylcholinesterase activity // inferred from mutant phenotype /// 0004104 // cholinesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from direct assay /// 0017171 // serine hydrolase activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred from direct assay /// 0042166 // acetylcholine binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from electronic annotation 205379_at NM_001236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001236.2 /DEF=Homo sapiens carbonyl reductase 3 (CBR3), mRNA. /FEA=mRNA /GEN=CBR3 /PROD=carbonyl reductase 3 /DB_XREF=gi:7108334 /UG=Hs.154510 carbonyl reductase 3 /FL=gb:BC002812.1 gb:AB004854.1 gb:NM_001236.2 NM_001236 carbonyl reductase 3 CBR3 874 NM_001236 0008152 // metabolic process // inferred from electronic annotation /// 0042376 // phylloquinone catabolic process // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000253 // 3-keto sterol reductase activity // inferred from electronic annotation /// 0004090 // carbonyl reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from direct assay 205380_at NM_002614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002614.1 /DEF=Homo sapiens PDZ domain containing 1 (PDZK1), mRNA. /FEA=mRNA /GEN=PDZK1 /PROD=PDZ domain containing 1 /DB_XREF=gi:4505702 /UG=Hs.15456 PDZ domain containing 1 /FL=gb:AF012281.1 gb:NM_002614.1 NM_002614 PDZ domain containing 1 PDZK1 5174 NM_001201325 /// NM_001201326 /// NM_002614 /// XM_005272968 /// XM_005272969 /// XM_005272970 0006810 // transport // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0015879 // carnitine transport // inferred from direct assay /// 0015893 // drug transport // non-traceable author statement /// 0034767 // positive regulation of ion transmembrane transport // inferred from direct assay /// 0044070 // regulation of anion transport // inferred from sequence or structural similarity /// 0090002 // establishment of protein localization to plasma membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005124 // scavenger receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 205381_at NM_005824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005824.1 /DEF=Homo sapiens 37 kDa leucine-rich repeat (LRR) protein (P37NB), mRNA. /FEA=mRNA /GEN=P37NB /PROD=37 kDa leucine-rich repeat (LRR) protein /DB_XREF=gi:5031970 /UG=Hs.155545 37 kDa leucine-rich repeat (LRR) protein /FL=gb:U32907.1 gb:NM_005824.1 NM_005824 leucine rich repeat containing 17 LRRC17 10234 NM_001031692 /// NM_005824 /// XM_005250108 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0033687 // osteoblast proliferation // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from sequence or structural similarity /// 0048539 // bone marrow development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 205382_s_at NM_001928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001928.1 /DEF=Homo sapiens D component of complement (adipsin) (DF), mRNA. /FEA=mRNA /GEN=DF /PROD=adipsincomplement factor D precursor /DB_XREF=gi:4503308 /UG=Hs.155597 D component of complement (adipsin) /FL=gb:M84526.1 gb:NM_001928.1 NM_001928 complement factor D (adipsin) CFD 1675 NM_001928 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205383_s_at NM_015642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015642.1 /DEF=Homo sapiens zinc finger protein 288 (ZNF288), mRNA. /FEA=mRNA /GEN=ZNF288 /PROD=zinc finger protein 288 /DB_XREF=gi:7661651 /UG=Hs.159456 zinc finger protein 288 /FL=gb:AL050276.1 gb:NM_015642.1 NM_015642 zinc finger and BTB domain containing 20 ZBTB20 26137 NM_001164342 /// NM_001164343 /// NM_001164344 /// NM_001164345 /// NM_001164346 /// NM_001164347 /// NM_015642 /// NR_121662 /// XM_005247339 /// XM_005247340 /// XM_005247341 /// XM_005247342 /// XM_005247343 /// XM_006713577 /// XM_006713578 /// XM_006713579 /// XM_006713580 /// XM_006713581 /// XM_006713833 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205384_at NM_005031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005031.2 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 1 (phospholemman) (FXYD1), transcript variant a, mRNA. /FEA=mRNA /GEN=FXYD1 /PROD=phospholemman, isoform a precursor /DB_XREF=gi:11612671 /UG=Hs.160318 FXYD domain-containing ion transport regulator 1 (phospholemman) /FL=gb:NM_021902.1 gb:NM_005031.2 gb:U72245.1 NM_005031 FXYD domain containing ion transport regulator 1 FXYD1 5348 NM_001278717 /// NM_001278718 /// NM_005031 /// NM_021902 /// XM_005258991 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 205385_at M92424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M92424.1 /DEF=Human p53-associated mRNA, complete cds. /FEA=mRNA /GEN=p53 associated /DB_XREF=gi:338308 /UG=Hs.170027 mouse double minute 2, human homolog of; p53-binding protein /FL=gb:M92424.1 gb:NM_002392.1 M92424 MDM2 proto-oncogene, E3 ubiquitin protein ligase MDM2 4193 NM_001145336 /// NM_001145337 /// NM_001145339 /// NM_001145340 /// NM_001278462 /// NM_002392 /// NM_006878 /// NM_006879 /// NM_006880 /// NM_006881 /// NM_006882 /// NM_032739 /// XM_005268872 /// XM_006719399 /// XM_006719400 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018205 // peptidyl-lysine modification // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071301 // cellular response to vitamin B1 // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071494 // cellular response to UV-C // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 205386_s_at NM_002392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002392.1 /DEF=Homo sapiens mouse double minute 2, human homolog of; p53-binding protein (MDM2), transcript variant MDM2, mRNA. /FEA=mRNA /GEN=MDM2 /PROD=mouse double minute 2, human homolog of, fulllength protein isoform /DB_XREF=gi:4505136 /UG=Hs.170027 mouse double minute 2, human homolog of; p53-binding protein /FL=gb:M92424.1 gb:NM_002392.1 NM_002392 MDM2 proto-oncogene, E3 ubiquitin protein ligase MDM2 4193 NM_001145336 /// NM_001145337 /// NM_001145339 /// NM_001145340 /// NM_001278462 /// NM_002392 /// NM_006878 /// NM_006879 /// NM_006880 /// NM_006881 /// NM_006882 /// NM_032739 /// XM_005268872 /// XM_006719399 /// XM_006719400 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018205 // peptidyl-lysine modification // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071301 // cellular response to vitamin B1 // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071494 // cellular response to UV-C // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 205387_s_at NM_000737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000737.1 /DEF=Homo sapiens chorionic gonadotropin, beta polypeptide (CGB), mRNA. /FEA=mRNA /GEN=CGB /PROD=chorionic gonadotropin, beta polypeptide /DB_XREF=gi:4502788 /UG=Hs.172944 chorionic gonadotropin, beta polypeptide /FL=gb:J00117.1 gb:NM_000737.1 NM_000737 chorionic gonadotropin, beta polypeptide /// chorionic gonadotropin, beta polypeptide 1 /// chorionic gonadotropin, beta polypeptide 5 /// chorionic gonadotropin, beta polypeptide 7 /// chorionic gonadotropin, beta polypeptide 8 CGB /// CGB1 /// CGB5 /// CGB7 /// CGB8 1082 /// 93659 /// 94027 /// 94115 /// 114335 NM_000737 /// NM_033043 /// NM_033142 /// NM_033183 /// NM_033377 /// XM_005258423 /// XM_005258478 /// XM_005259423 /// XM_005259425 /// XM_005259426 /// XM_006723505 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0016486 // peptide hormone processing // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 205388_at NM_003279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003279.1 /DEF=Homo sapiens troponin C2, fast (TNNC2), mRNA. /FEA=mRNA /GEN=TNNC2 /PROD=troponin C2, fast /DB_XREF=gi:4507616 /UG=Hs.182421 troponin C2, fast /FL=gb:M22307.1 gb:BC005323.1 gb:NM_003279.1 NM_003279 troponin C type 2 (fast) TNNC2 7125 NM_003279 0003009 // skeletal muscle contraction // inferred from direct assay /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205389_s_at AI659683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659683 /FEA=EST /DB_XREF=gi:4763253 /DB_XREF=est:tu25e07.x1 /CLONE=IMAGE:2252100 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_000037.2 gb:M28880.1 AI659683 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 205390_s_at NM_000037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000037.2 /DEF=Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 3, mRNA. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin 1, isoform 3 /DB_XREF=gi:10947039 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_000037.2 gb:M28880.1 NM_000037 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 205391_x_at M28880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M28880.1 /DEF=Human erythroid ankyrin mRNA, complete cds. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin /DB_XREF=gi:178645 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_000037.2 gb:M28880.1 M28880 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 205392_s_at NM_004166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004166.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 14 (SCYA14), mRNA. /FEA=mRNA /GEN=SCYA14 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 14 /DB_XREF=gi:4759069 /UG=Hs.20144 small inducible cytokine subfamily A (Cys-Cys), member 14 /FL=gb:NM_004166.1 NM_004166 chemokine (C-C motif) ligand 14 /// CCL15-CCL14 readthrough (NMD candidate) CCL14 /// CCL15-CCL14 6358 /// 348249 NM_004166 /// NM_032962 /// NM_032963 /// NR_027921 /// NR_027922 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay 205393_s_at NM_001274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001274.1 /DEF=Homo sapiens CHK1 (checkpoint, S.pombe) homolog (CHEK1), mRNA. /FEA=mRNA /GEN=CHEK1 /PROD=CHK1 (checkpoint, S.pombe) homolog /DB_XREF=gi:4502802 /UG=Hs.20295 CHK1 (checkpoint, S.pombe) homolog /FL=gb:AF016582.1 gb:NM_001274.1 NM_001274 checkpoint kinase 1 CHEK1 1111 NM_001114121 /// NM_001114122 /// NM_001244846 /// NM_001274 /// NR_045204 /// NR_045205 /// XM_006718759 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0010767 // regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035407 // histone H3-T11 phosphorylation // inferred from direct assay /// 0035407 // histone H3-T11 phosphorylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0046602 // regulation of mitotic centrosome separation // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from electronic annotation /// 0090399 // replicative senescence // non-traceable author statement /// 2000615 // regulation of histone H3-K9 acetylation // inferred from sequence or structural similarity 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035402 // histone kinase activity (H3-T11 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 205394_at NM_001274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001274.1 /DEF=Homo sapiens CHK1 (checkpoint, S.pombe) homolog (CHEK1), mRNA. /FEA=mRNA /GEN=CHEK1 /PROD=CHK1 (checkpoint, S.pombe) homolog /DB_XREF=gi:4502802 /UG=Hs.20295 CHK1 (checkpoint, S.pombe) homolog /FL=gb:AF016582.1 gb:NM_001274.1 NM_001274 checkpoint kinase 1 CHEK1 1111 NM_001114121 /// NM_001114122 /// NM_001244846 /// NM_001274 /// NR_045204 /// NR_045205 /// XM_006718759 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0010767 // regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035407 // histone H3-T11 phosphorylation // inferred from direct assay /// 0035407 // histone H3-T11 phosphorylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0046602 // regulation of mitotic centrosome separation // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from electronic annotation /// 0090399 // replicative senescence // non-traceable author statement /// 2000615 // regulation of histone H3-K9 acetylation // inferred from sequence or structural similarity 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035402 // histone kinase activity (H3-T11 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 205395_s_at NM_005590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005590.1 /DEF=Homo sapiens meiotic recombination (S. cerevisiae) 11 homolog A (MRE11A), mRNA. /FEA=mRNA /GEN=MRE11A /PROD=meiotic recombination (S. cerevisiae) 11 homologA /DB_XREF=gi:5031920 /UG=Hs.20555 meiotic recombination (S. cerevisiae) 11 homolog A /FL=gb:U37359.1 gb:NM_005590.1 NM_005590 MRE11 meiotic recombination 11 homolog A (S. cerevisiae) MRE11A 4361 NM_005590 /// NM_005591 /// XM_005274007 /// XM_005274008 /// XM_006718842 0000019 // regulation of mitotic recombination // traceable author statement /// 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // not recorded /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006289 // nucleotide-excision repair // not recorded /// 0006302 // double-strand break repair // not recorded /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // not recorded /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // not recorded /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030870 // Mre11 complex // inferred from direct assay /// 0030870 // Mre11 complex // non-traceable author statement /// 0035861 // site of double-strand break // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // traceable author statement /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // traceable author statement /// 0004519 // endonuclease activity // not recorded /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation 205396_at BF971416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF971416 /FEA=EST /DB_XREF=gi:12338631 /DB_XREF=est:602272936F1 /CLONE=IMAGE:4361120 /UG=Hs.211578 MAD (mothers against decapentaplegic, Drosophila) homolog 3 /FL=gb:U76622.1 gb:U68019.1 gb:NM_005902.1 BF971416 SMAD family member 3 SMAD3 4088 NM_001145102 /// NM_001145103 /// NM_001145104 /// NM_005902 /// XM_006720506 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006955 // immune response // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032916 // positive regulation of transforming growth factor beta3 production // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from mutant phenotype /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 205397_x_at U76622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U76622.1 /DEF=Human mad homolog JV15-2 mRNA, complete cds. /FEA=mRNA /GEN=JV15-2 /PROD=JV15-2 /DB_XREF=gi:1673576 /UG=Hs.211578 MAD (mothers against decapentaplegic, Drosophila) homolog 3 /FL=gb:U76622.1 gb:U68019.1 gb:NM_005902.1 U76622 SMAD family member 3 SMAD3 4088 NM_001145102 /// NM_001145103 /// NM_001145104 /// NM_005902 /// XM_006720506 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006955 // immune response // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032916 // positive regulation of transforming growth factor beta3 production // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from mutant phenotype /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 205398_s_at NM_005902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005902.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 3 (MADH3), mRNA. /FEA=mRNA /GEN=MADH3 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 3 /DB_XREF=gi:5174512 /UG=Hs.211578 MAD (mothers against decapentaplegic, Drosophila) homolog 3 /FL=gb:U76622.1 gb:U68019.1 gb:NM_005902.1 NM_005902 SMAD family member 3 SMAD3 4088 NM_001145102 /// NM_001145103 /// NM_001145104 /// NM_005902 /// XM_006720506 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006955 // immune response // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032916 // positive regulation of transforming growth factor beta3 production // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from mutant phenotype /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 205399_at NM_004734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004734.1 /DEF=Homo sapiens doublecortin and CaM kinase-like 1 (DCAMKL1), mRNA. /FEA=mRNA /GEN=DCAMKL1 /PROD=doublecortin and CaM kinase-like 1 /DB_XREF=gi:4758127 /UG=Hs.21355 doublecortin and CaM kinase-like 1 /FL=gb:AB002367.1 gb:NM_004734.1 NM_004734 doublecortin-like kinase 1 DCLK1 9201 NM_001195415 /// NM_001195416 /// NM_001195430 /// NM_004734 /// XM_005266592 /// XM_006719893 0001764 // neuron migration // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0016197 // endosomal transport // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205400_at NM_000377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000377.1 /DEF=Homo sapiens Wiskott-Aldrich syndrome (eczema-thrombocytopenia) (WAS), mRNA. /FEA=mRNA /GEN=WAS /PROD=Wiskott-Aldrich syndrome protein /DB_XREF=gi:4507908 /UG=Hs.2157 Wiskott-Aldrich syndrome (eczema-thrombocytopenia) /FL=gb:NM_000377.1 gb:U12707.1 gb:U19927.1 NM_000377 Wiskott-Aldrich syndrome WAS 7454 NM_000377 0006461 // protein complex assembly // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016197 // endosomal transport // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 205401_at NM_003659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003659.1 /DEF=Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA. /FEA=mRNA /GEN=AGPS /PROD=alkylglycerone phosphate synthase precursor /DB_XREF=gi:4501992 /UG=Hs.22580 alkylglycerone phosphate synthase /FL=gb:NM_003659.1 NM_003659 alkylglycerone phosphate synthase AGPS 8540 NM_003659 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0008611 // ether lipid biosynthetic process // inferred from electronic annotation /// 0008611 // ether lipid biosynthetic process // inferred from sequence or structural similarity /// 0008611 // ether lipid biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008609 // alkylglycerone-phosphate synthase activity // inferred from direct assay /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity 205402_x_at NM_002770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002770.1 /DEF=Homo sapiens protease, serine, 2 (trypsin 2) (PRSS2), mRNA. /FEA=mRNA /GEN=PRSS2 /PROD=protease, serine, 2 (trypsin 2) /DB_XREF=gi:4506146 /UG=Hs.241561 protease, serine, 2 (trypsin 2) /FL=gb:NM_002770.1 gb:M27602.1 NM_002770 protease, serine, 2 (trypsin 2) PRSS2 5645 NM_002770 /// XM_005276996 /// XM_005276998 /// XM_006716052 /// XM_006716053 /// XM_006725058 0006508 // proteolysis // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205403_at NM_004633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004633.1 /DEF=Homo sapiens interleukin 1 receptor, type II (IL1R2), mRNA. /FEA=mRNA /GEN=IL1R2 /PROD=interleukin 1 receptor, type II /DB_XREF=gi:4758597 /UG=Hs.25333 interleukin 1 receptor, type II /FL=gb:U74649.1 gb:NM_004633.1 NM_004633 interleukin 1 receptor, type II IL1R2 7850 NM_001261419 /// NM_004633 /// NM_173343 /// NR_048564 /// XM_006712733 /// XM_006712734 /// XM_006712735 /// XM_006712736 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004908 // interleukin-1 receptor activity // traceable author statement /// 0004910 // interleukin-1, Type II, blocking receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205404_at NM_005525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005525.1 /DEF=Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), mRNA. /FEA=mRNA /GEN=HSD11B1 /PROD=hydroxysteroid (11-beta) dehydrogenase 1 /DB_XREF=gi:5031764 /UG=Hs.275215 hydroxysteroid (11-beta) dehydrogenase 1 /FL=gb:NM_005525.1 NM_005525 hydroxysteroid (11-beta) dehydrogenase 1 HSD11B1 3290 NM_001206741 /// NM_005525 /// NM_181755 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003845 // 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0070524 // 11-beta-hydroxysteroid dehydrogenase (NADP+) activity // inferred from electronic annotation 205405_at NM_003966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003966.1 /DEF=Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (SEMA5A), mRNA. /FEA=mRNA /GEN=SEMA5A /PROD=sema domain, seven thrombospondin repeats (type1 and type 1-like), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 5A /DB_XREF=gi:4506880 /UG=Hs.27621 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A /FL=gb:U52840.1 gb:NM_003966.1 NM_003966 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A SEMA5A 9037 NM_003966 /// XM_006714506 /// XM_006714507 /// XM_006714508 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0021536 // diencephalon development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from sequence or structural similarity /// 0035413 // positive regulation of catenin import into nucleus // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from sequence or structural similarity /// 1990256 // signal clustering // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from sequence or structural similarity /// 0035373 // chondroitin sulfate proteoglycan binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity /// 0045545 // syndecan binding // inferred from sequence or structural similarity 205406_s_at NM_017425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017425.1 /DEF=Homo sapiens sperm autoantigenic protein 17 (SPA17), mRNA. /FEA=mRNA /GEN=SPA17 /PROD=sperm autoantigenic protein 17 /DB_XREF=gi:8394342 /UG=Hs.286233 sperm autoantigenic protein 17 /FL=gb:NM_017425.1 NM_017425 sperm autoantigenic protein 17 SPA17 53340 NM_017425 0001539 // cilium or flagellum-dependent cell motility // inferred from direct assay /// 0003351 // epithelial cilium movement // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation 205407_at NM_021111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021111.1 /DEF=Homo sapiens reversion-inducing-cysteine-rich protein with kazal motifs (RECK), mRNA. /FEA=mRNA /GEN=RECK /PROD=RECK protein precursor /DB_XREF=gi:11863155 /UG=Hs.29640 reversion-inducing-cysteine-rich protein with kazal motifs /FL=gb:NM_021111.1 gb:D50406.1 NM_021111 reversion-inducing-cysteine-rich protein with kazal motifs RECK 8434 NM_021111 /// XM_006716879 0001955 // blood vessel maturation // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205408_at NM_004641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004641.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 (AF10), mRNA. /FEA=mRNA /GEN=AF10 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 10 /DB_XREF=gi:4757725 /UG=Hs.301209 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 /FL=gb:NM_004641.1 gb:U13948.1 NM_004641 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 MLLT10 8028 NM_001009569 /// NM_001195626 /// NM_001195627 /// NM_001195628 /// NM_001195630 /// NM_004641 /// XM_005252605 /// XM_005252606 /// XM_005252608 /// XM_005252609 /// XM_005252610 /// XM_005252611 /// XM_005252612 /// XM_006717509 /// XR_428648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205409_at NM_005253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005253.1 /DEF=Homo sapiens FOS-like antigen 2 (FOSL2), mRNA. /FEA=mRNA /GEN=FOSL2 /PROD=FOS-like antigen 2 /DB_XREF=gi:4885244 /UG=Hs.301612 FOS-like antigen 2 /FL=gb:NM_005253.1 NM_005253 FOS-like antigen 2 FOSL2 2355 NM_005253 /// XM_005264231 /// XM_006711976 /// XM_006711977 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205410_s_at NM_001684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001684.1 /DEF=Homo sapiens ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), mRNA. /FEA=mRNA /GEN=ATP2B4 /PROD=ATPase, Ca++ transporting, plasma membrane 4 /DB_XREF=gi:4502288 /UG=Hs.305923 ATPase, Ca++ transporting, plasma membrane 4 /FL=gb:M25874.1 gb:NM_001684.1 NM_001684 ATPase, Ca++ transporting, plasma membrane 4 ATP2B4 493 NM_001001396 /// NM_001684 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // non-traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred by curator 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 205411_at NM_006282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006282.1 /DEF=Homo sapiens serinethreonine kinase 4 (STK4), mRNA. /FEA=mRNA /GEN=STK4 /PROD=serinethreonine kinase 4 /DB_XREF=gi:5454095 /UG=Hs.35140 serinethreonine kinase 4 /FL=gb:U18297.1 gb:U60207.1 gb:NM_006282.1 NM_006282 serine/threonine kinase 4 STK4 6789 NM_006282 /// XM_005260530 /// XM_005260531 /// XM_005260532 /// XM_005260533 /// XM_006723870 0000902 // cell morphogenesis // inferred from direct assay /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0003157 // endocardium development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060215 // primitive hemopoiesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043539 // protein serine/threonine kinase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay 205412_at NM_000019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000019.1 /DEF=Homo sapiens acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACAT1 /PROD=acetyl-Coenzyme A acetyltransferase 1 precursor /DB_XREF=gi:4557236 /UG=Hs.37 acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) /FL=gb:NM_000019.1 NM_000019 acetyl-CoA acetyltransferase 1 ACAT1 38 NM_000019 /// XM_006718834 /// XM_006718835 0001889 // liver development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // traceable author statement /// 0046952 // ketone body catabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0072229 // metanephric proximal convoluted tubule development // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003985 // acetyl-CoA C-acetyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 205413_at NM_001584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001584.1 /DEF=Homo sapiens chromosome 11 open reading frame 8 (C11ORF8), mRNA. /FEA=mRNA /GEN=C11ORF8 /PROD=chromosome 11 open reading frame 8 /DB_XREF=gi:4502484 /UG=Hs.46638 chromosome 11 open reading frame 8 /FL=gb:U57911.1 gb:NM_001584.1 NM_001584 metallophosphoesterase domain containing 2 MPPED2 744 NM_001145399 /// NM_001584 /// XM_005253110 /// XM_005253111 /// XM_005253112 /// XM_005253113 /// XM_005253114 /// XM_006718304 /// XM_006718305 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205414_s_at NM_014859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014859.1 /DEF=Homo sapiens KIAA0672 gene product (KIAA0672), mRNA. /FEA=mRNA /GEN=KIAA0672 /PROD=KIAA0672 gene product /DB_XREF=gi:7662241 /UG=Hs.6336 KIAA0672 gene product /FL=gb:AB014572.1 gb:NM_014859.1 NM_014859 Rho GTPase activating protein 44 ARHGAP44 9912 NM_014859 /// XM_005256888 /// XM_005256889 /// XM_005256890 /// XM_005256891 /// XM_006721615 0006887 // exocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 205415_s_at AI888099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI888099 /FEA=EST /DB_XREF=gi:5593263 /DB_XREF=est:wm41g03.x1 /CLONE=IMAGE:2438548 /UG=Hs.66521 Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) /FL=gb:NM_004993.2 gb:U64820.1 AI888099 ataxin 3 ATXN3 4287 NM_001024631 /// NM_001127696 /// NM_001127697 /// NM_001164774 /// NM_001164776 /// NM_001164777 /// NM_001164778 /// NM_001164779 /// NM_001164780 /// NM_001164781 /// NM_001164782 /// NM_004993 /// NM_030660 /// NR_028453 /// NR_028454 /// NR_028455 /// NR_028456 /// NR_028457 /// NR_028458 /// NR_028459 /// NR_028460 /// NR_028461 /// NR_028462 /// NR_028463 /// NR_028464 /// NR_028465 /// NR_028466 /// NR_028467 /// NR_028468 /// NR_028469 /// NR_028470 /// NR_031765 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010810 // regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035520 // monoubiquitinated protein deubiquitination // inferred from sequence or structural similarity /// 0035640 // exploration behavior // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042405 // nuclear inclusion body // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004843 // ubiquitin-specific protease activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 205416_s_at NM_004993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004993.2 /DEF=Homo sapiens Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) (MJD), transcript variant 1, mRNA. /FEA=mRNA /GEN=MJD /PROD=ataxin 3, isoform 1 /DB_XREF=gi:13518018 /UG=Hs.66521 Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) /FL=gb:NM_004993.2 gb:U64820.1 NM_004993 ataxin 3 ATXN3 4287 NM_001024631 /// NM_001127696 /// NM_001127697 /// NM_001164774 /// NM_001164776 /// NM_001164777 /// NM_001164778 /// NM_001164779 /// NM_001164780 /// NM_001164781 /// NM_001164782 /// NM_004993 /// NM_030660 /// NR_028453 /// NR_028454 /// NR_028455 /// NR_028456 /// NR_028457 /// NR_028458 /// NR_028459 /// NR_028460 /// NR_028461 /// NR_028462 /// NR_028463 /// NR_028464 /// NR_028465 /// NR_028466 /// NR_028467 /// NR_028468 /// NR_028469 /// NR_028470 /// NR_031765 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010810 // regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035520 // monoubiquitinated protein deubiquitination // inferred from sequence or structural similarity /// 0035640 // exploration behavior // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042405 // nuclear inclusion body // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004843 // ubiquitin-specific protease activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 205417_s_at NM_004393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004393.1 /DEF=Homo sapiens dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1), mRNA. /FEA=mRNA /GEN=DAG1 /PROD=dystroglycan 1 precursor /DB_XREF=gi:4758115 /UG=Hs.76111 dystroglycan 1 (dystrophin-associated glycoprotein 1) /FL=gb:L19711.1 gb:NM_004393.1 NM_004393 dystroglycan 1 (dystrophin-associated glycoprotein 1) DAG1 1605 NM_001165928 /// NM_001177634 /// NM_001177635 /// NM_001177636 /// NM_001177637 /// NM_001177638 /// NM_001177639 /// NM_001177640 /// NM_001177641 /// NM_001177642 /// NM_001177643 /// NM_001177644 /// NM_004393 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // inferred from direct assay /// 0007016 // cytoskeletal anchoring at plasma membrane // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016340 // calcium-dependent cell-matrix adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0021682 // nerve maturation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016011 // dystroglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070938 // contractile ring // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0002162 // dystroglycan binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0015631 // tubulin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from sequence or structural similarity /// 0051393 // alpha-actinin binding // inferred from direct assay 205418_at NM_002005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002005.2 /DEF=Homo sapiens feline sarcoma (Snyder-Theilen) viral (v-fes)Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog (FES), mRNA. /FEA=mRNA /GEN=FES /PROD=V-FES feline sarcoma viralV-FPS fujinami aviansarcoma viral oncogene homolog /DB_XREF=gi:13376997 /UG=Hs.7636 feline sarcoma (Snyder-Theilen) viral (v-fes)Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog /FL=gb:NM_002005.2 NM_002005 FES proto-oncogene, tyrosine kinase FES 2242 NM_001143783 /// NM_001143784 /// NM_001143785 /// NM_002005 /// XM_005254877 /// XM_005254880 /// XM_005254881 /// XM_005254882 /// XR_243205 /// XR_243206 0006468 // protein phosphorylation // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0043304 // regulation of mast cell degranulation // inferred from mutant phenotype /// 0045595 // regulation of cell differentiation // inferred from mutant phenotype /// 0045639 // positive regulation of myeloid cell differentiation // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060627 // regulation of vesicle-mediated transport // traceable author statement /// 2000145 // regulation of cell motility // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 205419_at NM_004951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004951.1 /DEF=Homo sapiens Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) (EBI2), mRNA. /FEA=mRNA /GEN=EBI2 /PROD=Epstein-Barr virus induced gene 2(lymphocyte-specific G protein-coupled receptor) /DB_XREF=gi:4826705 /UG=Hs.784 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) /FL=gb:L08177.1 gb:NM_004951.1 NM_004951 G protein-coupled receptor 183 GPR183 1880 NM_004951 0002313 // mature B cell differentiation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008142 // oxysterol binding // inferred from direct assay 205420_at NM_000288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000288.1 /DEF=Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA. /FEA=mRNA /GEN=PEX7 /PROD=peroxisomal biogenesis factor 7 /DB_XREF=gi:4505730 /UG=Hs.79993 peroxisomal biogenesis factor 7 /FL=gb:U76560.1 gb:U88871.1 gb:NM_000288.1 NM_000288 peroxisomal biogenesis factor 7 PEX7 5191 NM_000288 /// XM_005267019 /// XM_006715502 /// XM_006715503 0001764 // neuron migration // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008611 // ether lipid biosynthetic process // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005053 // peroxisome matrix targeting signal-2 binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 205421_at NM_021977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021977.1 /DEF=Homo sapiens solute carrier family 22 (extraneuronal monoamine transporter), member 3 (SLC22A3), mRNA. /FEA=mRNA /GEN=SLC22A3 /PROD=solute carrier family 22 (extraneuronalmonoamine transporter), member 3 /DB_XREF=gi:11415037 /UG=Hs.81086 solute carrier family 22 (extraneuronal monoamine transporter), member 3 /FL=gb:NM_021977.1 NM_021977 solute carrier family 22 (organic cation transporter), member 3 SLC22A3 6581 NM_021977 /// XM_005267106 /// XM_005267107 /// XR_245546 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015697 // quaternary ammonium group transport // inferred from direct assay /// 0015844 // monoamine transport // inferred from electronic annotation /// 0015872 // dopamine transport // inferred from electronic annotation /// 0032098 // regulation of appetite // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051608 // histamine transport // inferred from electronic annotation /// 0051615 // histamine uptake // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005329 // dopamine transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from direct assay /// 0019534 // toxin transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 205422_s_at NM_004791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004791.1 /DEF=Homo sapiens integrin, beta-like 1 (with EGF-like repeat domains) (ITGBL1), mRNA. /FEA=mRNA /GEN=ITGBL1 /PROD=integrin, beta-like 1 (with EGF-like repeatdomains) /DB_XREF=gi:4758613 /UG=Hs.82582 integrin, beta-like 1 (with EGF-like repeat domains) /FL=gb:AF072752.1 gb:NM_004791.1 NM_004791 integrin, beta-like 1 (with EGF-like repeat domains) ITGBL1 9358 NM_001271754 /// NM_001271755 /// NM_001271756 /// NM_004791 /// XM_005254100 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205423_at NM_001127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001127.1 /DEF=Homo sapiens adaptor-related protein complex 1, beta 1 subunit (AP1B1), mRNA. /FEA=mRNA /GEN=AP1B1 /PROD=adaptor-related protein complex 1, beta 1subunit /DB_XREF=gi:4501972 /UG=Hs.89576 adaptor-related protein complex 1, beta 1 subunit /FL=gb:L13939.1 gb:NM_001127.1 NM_001127 adaptor-related protein complex 1, beta 1 subunit AP1B1 162 NM_001127 /// NM_001166019 /// NM_145730 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 205424_at NM_014726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014726.1 /DEF=Homo sapiens KIAA0775 gene product (KIAA0775), mRNA. /FEA=mRNA /GEN=KIAA0775 /PROD=KIAA0775 gene product /DB_XREF=gi:7662301 /UG=Hs.94790 KIAA0775 gene product /FL=gb:AB018318.1 gb:NM_014726.1 NM_014726 TBK1 binding protein 1 TBKBP1 9755 NM_014726 /// XM_005257859 /// XM_005257860 /// XM_005257861 /// XM_005257862 /// XM_006722199 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205425_at NM_005338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005338.3 /DEF=Homo sapiens huntingtin interacting protein 1 (HIP1), mRNA. /FEA=mRNA /GEN=HIP1 /PROD=huntingtin interacting protein 1 /DB_XREF=gi:12545385 /UG=Hs.97206 huntingtin interacting protein 1 /FL=gb:NM_005338.3 gb:U79734.1 NM_005338 huntingtin interacting protein 1 HIP1 3092 NM_001243198 /// NM_005338 /// XM_005250304 /// XM_005250305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 205426_s_at U79734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79734.1 /DEF=Human huntingtin interacting protein (HIP1) mRNA, complete cds. /FEA=mRNA /GEN=HIP1 /PROD=huntingtin interacting protein 1 /DB_XREF=gi:2072422 /UG=Hs.97206 huntingtin interacting protein 1 /FL=gb:NM_005338.3 gb:U79734.1 U79734 huntingtin interacting protein 1 HIP1 3092 NM_001243198 /// NM_005338 /// XM_005250304 /// XM_005250305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 205427_at NM_005649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005649.1 /DEF=Homo sapiens transcription factor 17 (TCF17), mRNA. /FEA=mRNA /GEN=TCF17 /PROD=transcription factor 17 /DB_XREF=gi:5032162 /UG=Hs.100932 transcription factor 17 /FL=gb:D89928.1 gb:AF116030.1 gb:NM_005649.1 NM_005649 zinc finger protein 354A ZNF354A 6940 NM_005649 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007576 // nucleolar fragmentation // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0051593 // response to folic acid // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205428_s_at NM_001740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001740.2 /DEF=Homo sapiens calbindin 2, (29kD, calretinin) (CALB2), transcript variant CALB2, mRNA. /FEA=mRNA /GEN=CALB2 /PROD=calbindin 2, full length protein isoform /DB_XREF=gi:6031158 /UG=Hs.106857 calbindin 2, (29kD, calretinin) /FL=gb:NM_001740.2 NM_001740 calbindin 2 CALB2 794 NM_001740 /// NM_007087 /// NM_007088 /// NR_027910 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005921 // gap junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205429_s_at NM_016447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016447.1 /DEF=Homo sapiens MAGUK protein p55T; Protein Associated with Lins 2 (LOC51678), mRNA. /FEA=mRNA /GEN=LOC51678 /PROD=MAGUK protein p55T; Protein Associated with Lins2 /DB_XREF=gi:7706402 /UG=Hs.108931 MAGUK protein p55T; Protein Associated with Lins 2 /FL=gb:AF162130.2 gb:NM_016447.1 NM_016447 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) MPP6 51678 NM_016447 /// XM_005249775 /// XM_006715738 /// XM_006715739 /// XM_006715740 /// XM_006715741 0006461 // protein complex assembly // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation 205430_at AL133386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133386 /DEF=Human DNA sequence from clone RP1-181C24 on chromosome 6p11.1-12.2. Contains the 3 end of the BMP5 gene for bone morphogenetic protein 5, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:6807532 /UG=Hs.1104 bone morphogenetic protein 5 /FL=gb:NM_021073.1 gb:M60314.1 AL133386 bone morphogenetic protein 5 BMP5 653 NM_021073 /// XM_005249304 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0071676 // negative regulation of mononuclear cell migration // non-traceable author statement /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000105 // positive regulation of DNA-dependent DNA replication // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0031988 // membrane-bounded vesicle // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0070700 // BMP receptor binding // inferred from physical interaction 205431_s_at NM_021073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021073.1 /DEF=Homo sapiens bone morphogenetic protein 5 (BMP5), mRNA. /FEA=mRNA /GEN=BMP5 /PROD=bone morphogenetic protein 5 /DB_XREF=gi:10835090 /UG=Hs.1104 bone morphogenetic protein 5 /FL=gb:NM_021073.1 gb:M60314.1 NM_021073 bone morphogenetic protein 5 BMP5 653 NM_021073 /// XM_005249304 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0071676 // negative regulation of mononuclear cell migration // non-traceable author statement /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000105 // positive regulation of DNA-dependent DNA replication // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0031988 // membrane-bounded vesicle // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0070700 // BMP receptor binding // inferred from physical interaction 205432_at NM_002557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002557.1 /DEF=Homo sapiens oviductal glycoprotein 1, 120kD (mucin 9, oviductin) (OVGP1), mRNA. /FEA=mRNA /GEN=OVGP1 /PROD=oviductal glycoprotein 1, 120kD (mucin 9,oviductin) /DB_XREF=gi:4505534 /UG=Hs.1154 oviductal glycoprotein 1, 120kD (mucin 9, oviductin) /FL=gb:U09550.1 gb:NM_002557.1 NM_002557 oviductal glycoprotein 1, 120kDa OVGP1 5016 NM_002557 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement 0005829 // cytosol // traceable author statement /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from electronic annotation 205433_at NM_000055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000055.1 /DEF=Homo sapiens butyrylcholinesterase (BCHE), mRNA. /FEA=mRNA /GEN=BCHE /PROD=butyrylcholinesterase precursor /DB_XREF=gi:4557350 /UG=Hs.1327 butyrylcholinesterase /FL=gb:M16541.1 gb:M16474.1 gb:NM_000055.1 NM_000055 butyrylcholinesterase BCHE 590 NM_000055 /// XM_005247685 0007271 // synaptic transmission, cholinergic // not recorded /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014016 // neuroblast differentiation // inferred from electronic annotation /// 0019695 // choline metabolic process // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050783 // cocaine metabolic process // traceable author statement /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // non-traceable author statement /// 0003824 // catalytic activity // non-traceable author statement /// 0003990 // acetylcholinesterase activity // not recorded /// 0003990 // acetylcholinesterase activity // inferred from sequence or structural similarity /// 0004104 // cholinesterase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement /// 0033265 // choline binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 205434_s_at AW451954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451954 /FEA=EST /DB_XREF=gi:6992730 /DB_XREF=est:UI-H-BI3-alt-h-06-0-UI.s1 /CLONE=IMAGE:3068771 /UG=Hs.135941 KIAA1048 protein /FL=gb:AB028971.1 gb:NM_014911.1 AW451954 AP2 associated kinase 1 AAK1 22848 NM_014911 0006468 // protein phosphorylation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 205435_s_at NM_014911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014911.1 /DEF=Homo sapiens KIAA1048 protein (KIAA1048), mRNA. /FEA=mRNA /GEN=KIAA1048 /PROD=KIAA1048 protein /DB_XREF=gi:7662461 /UG=Hs.135941 KIAA1048 protein /FL=gb:AB028971.1 gb:NM_014911.1 NM_014911 AP2 associated kinase 1 AAK1 22848 NM_014911 0006468 // protein phosphorylation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 205436_s_at NM_002105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002105.1 /DEF=Homo sapiens H2A histone family, member X (H2AFX), mRNA. /FEA=mRNA /GEN=H2AFX /PROD=H2A histone family, member X /DB_XREF=gi:4504252 /UG=Hs.147097 H2A histone family, member X /FL=gb:BC004915.1 gb:NM_002105.1 NM_002105 H2A histone family, member X H2AFX 3014 NM_002105 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // non-traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010212 // response to ionizing radiation // non-traceable author statement /// 0045739 // positive regulation of DNA repair // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // inferred from electronic annotation /// 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205437_at NM_006385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006385.1 /DEF=Homo sapiens zinc finger protein 211 (ZNF211), mRNA. /FEA=mRNA /GEN=ZNF211 /PROD=zinc finger protein 211 /DB_XREF=gi:5454175 /UG=Hs.15110 zinc finger protein 211 /FL=gb:U38904.1 gb:NM_006385.1 NM_006385 zinc finger protein 211 ZNF211 10520 NM_001265597 /// NM_001265598 /// NM_001265599 /// NM_001265600 /// NM_001290231 /// NM_006385 /// NM_198855 /// NR_049752 /// NR_049753 /// NR_049754 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205438_at NM_007039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007039.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 21 (PTPN21), mRNA. /FEA=mRNA /GEN=PTPN21 /PROD=protein tyrosine phosphatase, non-receptor type21 /DB_XREF=gi:5902031 /UG=Hs.155693 protein tyrosine phosphatase, non-receptor type 21 /FL=gb:NM_007039.1 NM_007039 protein tyrosine phosphatase, non-receptor type 21 PTPN21 11099 NM_007039 /// XM_005267287 /// XM_006720011 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 205439_at NM_000854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000854.2 /DEF=Homo sapiens glutathione S-transferase theta 2 (GSTT2), mRNA. /FEA=mRNA /GEN=GSTT2 /PROD=glutathione S-transferase theta 2 /DB_XREF=gi:7669495 /UG=Hs.1581 glutathione S-transferase theta 2 /FL=gb:BC002415.1 gb:L38503.1 gb:NM_000854.2 NM_000854 glutathione S-transferase theta 2 GSTT2 2953 NM_000854 /// XM_005261590 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205440_s_at NM_000909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000909.1 /DEF=Homo sapiens neuropeptide Y receptor Y1 (NPY1R), mRNA. /FEA=mRNA /GEN=NPY1R /PROD=neuropeptide Y receptor Y1 /DB_XREF=gi:4505444 /UG=Hs.169266 neuropeptide Y receptor Y1 /FL=gb:M84755.1 gb:M88461.1 gb:NM_000909.1 NM_000909 neuropeptide Y receptor Y1 NPY1R 4886 NM_000909 /// XM_005263031 /// XM_005263032 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0001602 // pancreatic polypeptide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205441_at NM_024578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024578.1 /DEF=Homo sapiens hypothetical protein FLJ22709 (FLJ22709), mRNA. /FEA=mRNA /GEN=FLJ22709 /PROD=hypothetical protein FLJ22709 /DB_XREF=gi:13375755 /UG=Hs.17258 hypothetical protein FLJ22709 /FL=gb:NM_024578.1 NM_024578 occludin/ELL domain containing 1 OCEL1 79629 NM_024578 /// XM_005260079 /// XM_006722899 205442_at NM_021647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021647.1 /DEF=Homo sapiens KIAA0626 gene product (KIAA0626), mRNA. /FEA=mRNA /GEN=KIAA0626 /PROD=KIAA0626 gene product /DB_XREF=gi:11067364 /UG=Hs.178121 KIAA0626 gene product /FL=gb:NM_021647.1 gb:AB014526.1 NM_021647 uncharacterized LOC101928198 /// microfibrillar-associated protein 3-like LOC101928198 /// MFAP3L 9848 /// 101928198 NM_001009554 /// NM_021647 /// XM_005263366 /// XM_005263368 /// XM_005263369 /// XM_005263370 /// XM_005263371 /// XM_006714423 /// XM_006714424 /// XM_006714425 /// XM_006714426 /// XM_006714427 /// XM_006714428 /// XR_244749 /// XR_249692 /// XR_251689 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205443_at NM_003082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003082.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 1, 43kD (SNAPC1), mRNA. /FEA=mRNA /GEN=SNAPC1 /PROD=small nuclear RNA activating complex,polypeptide 1, 43kD /DB_XREF=gi:4507100 /UG=Hs.179312 small nuclear RNA activating complex, polypeptide 1, 43kD /FL=gb:U44754.1 gb:NM_003082.1 NM_003082 small nuclear RNA activating complex, polypeptide 1, 43kDa SNAPC1 6617 NM_003082 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation 205444_at NM_004320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004320.1 /DEF=Homo sapiens ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), mRNA. /FEA=mRNA /GEN=ATP2A1 /PROD=ATPase, Ca++ transporting, cardiac muscle, fasttwitch 1 /DB_XREF=gi:10835219 /UG=Hs.183075 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 /FL=gb:NM_004320.1 NM_004320 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ATP2A1 487 NM_001286075 /// NM_004320 /// NM_173201 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006942 // regulation of striated muscle contraction // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from mutant phenotype /// 0031448 // positive regulation of fast-twitch skeletal muscle fiber contraction // inferred from direct assay /// 0032470 // positive regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0051659 // maintenance of mitochondrion location // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0070509 // calcium ion import // inferred from mutant phenotype /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0090076 // relaxation of skeletal muscle // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0016529 // sarcoplasmic reticulum // non-traceable author statement /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0031673 // H zone // inferred from direct assay /// 0031674 // I band // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred by curator /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0034704 // calcium channel complex // inferred by curator /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205445_at NM_000948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000948.1 /DEF=Homo sapiens prolactin (PRL), mRNA. /FEA=mRNA /GEN=PRL /PROD=prolactin /DB_XREF=gi:4506104 /UG=Hs.1905 prolactin /FL=gb:NM_000948.1 NM_000948 prolactin PRL 5617 NM_000948 /// NM_001163558 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007262 // STAT protein import into nucleus // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007567 // parturition // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from expression pattern /// 0042493 // response to drug // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation 0005148 // prolactin receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205446_s_at NM_001880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001880.1 /DEF=Homo sapiens activating transcription factor 2 (ATF2), mRNA. /FEA=mRNA /GEN=ATF2 /PROD=activating transcription factor 2 /DB_XREF=gi:4503032 /UG=Hs.198166 activating transcription factor 2 /FL=gb:NM_001880.1 NM_001880 activating transcription factor 2 ATF2 1386 NM_001256090 /// NM_001256091 /// NM_001256092 /// NM_001256093 /// NM_001256094 /// NM_001880 /// NR_045768 /// NR_045769 /// NR_045770 /// NR_045771 /// NR_045772 /// NR_045773 /// NR_045774 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006970 // response to osmotic stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // inferred from mutant phenotype /// 0032915 // positive regulation of transforming growth factor beta2 production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred by curator /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205447_s_at BE222201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222201 /FEA=EST /DB_XREF=gi:8909519 /DB_XREF=est:hu09a10.x1 /CLONE=IMAGE:3166074 /UG=Hs.211601 mitogen-activated protein kinase kinase kinase 12 /FL=gb:NM_006301.1 gb:U07358.1 BE222201 mitogen-activated protein kinase kinase kinase 12 MAP3K12 7786 NM_001193511 /// NM_006301 /// XM_005269138 /// XM_005269140 /// XM_006719588 /// XM_006719589 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from sequence or structural similarity /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // traceable author statement /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 205448_s_at NM_006301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006301.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 12 (MAP3K12), mRNA. /FEA=mRNA /GEN=MAP3K12 /PROD=mitogen-activated protein kinase kinase kinase12 /DB_XREF=gi:5454183 /UG=Hs.211601 mitogen-activated protein kinase kinase kinase 12 /FL=gb:NM_006301.1 gb:U07358.1 NM_006301 mitogen-activated protein kinase kinase kinase 12 MAP3K12 7786 NM_001193511 /// NM_006301 /// XM_005269138 /// XM_005269140 /// XM_006719588 /// XM_006719589 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from sequence or structural similarity /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // traceable author statement /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 205449_at NM_013299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013299.1 /DEF=Homo sapiens protein predicted by clone 23627 (HSU79266), mRNA. /FEA=mRNA /GEN=HSU79266 /PROD=protein predicted by clone 23627 /DB_XREF=gi:9558738 /UG=Hs.23642 protein predicted by clone 23627 /FL=gb:U79266.1 gb:NM_013299.1 NM_013299 SAC3 domain containing 1 SAC3D1 29901 NM_013299 /// XM_005273960 /// XM_005273961 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205450_at NM_002637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002637.1 /DEF=Homo sapiens phosphorylase kinase, alpha 1 (muscle) (PHKA1), mRNA. /FEA=mRNA /GEN=PHKA1 /PROD=phosphorylase kinase, alpha 1 (muscle) /DB_XREF=gi:4505778 /UG=Hs.2393 phosphorylase kinase, alpha 1 (muscle) /FL=gb:NM_002637.1 NM_002637 phosphorylase kinase, alpha 1 (muscle) PHKA1 5255 NM_001122670 /// NM_001172436 /// NM_002637 /// XM_006724661 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 205451_at NM_005938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005938.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7 (MLLT7), mRNA. /FEA=mRNA /GEN=MLLT7 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 7 /DB_XREF=gi:5174578 /UG=Hs.239663 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7 /FL=gb:NM_005938.1 NM_005938 forkhead box O4 FOXO4 4303 NM_001170931 /// NM_005938 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // not recorded /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048863 // stem cell differentiation // inferred from mutant phenotype /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from direct assay /// 0070317 // negative regulation of G0 to G1 transition // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype 205452_at NM_004855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004855.1 /DEF=Homo sapiens phosphatidylinositol glycan, class B (PIGB), mRNA. /FEA=mRNA /GEN=PIGB /PROD=phosphatidylinositol glycan, class B /DB_XREF=gi:4758917 /UG=Hs.247118 phosphatidylinositol glycan, class B /FL=gb:D42138.1 gb:NM_004855.1 NM_004855 phosphatidylinositol glycan anchor biosynthesis, class B PIGB 9488 NM_004855 /// XM_005254794 /// XM_005254795 /// XM_006720777 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000030 // mannosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 205453_at NM_002145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002145.1 /DEF=Homo sapiens homeo box B2 (HOXB2), mRNA. /FEA=mRNA /GEN=HOXB2 /PROD=homeo box B2 /DB_XREF=gi:4504464 /UG=Hs.2733 homeo box B2 /FL=gb:NM_002145.1 NM_002145 homeobox B2 HOXB2 3212 NM_002145 /// XM_005257275 /// XM_005257276 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021569 // rhombomere 3 development // inferred from electronic annotation /// 0021570 // rhombomere 4 development // inferred from electronic annotation /// 0021612 // facial nerve structural organization // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048857 // neural nucleus development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205454_at BC001777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001777.1 /DEF=Homo sapiens, hippocalcin, clone MGC:1822, mRNA, complete cds. /FEA=mRNA /PROD=hippocalcin /DB_XREF=gi:12804696 /UG=Hs.288654 hippocalcin /FL=gb:BC001777.1 gb:NM_002143.1 gb:D16593.1 BC001777 hippocalcin HPCA 3208 NM_002143 /// XM_005270792 0048839 // inner ear development // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205455_at NM_002447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002447.1 /DEF=Homo sapiens macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R), mRNA. /FEA=mRNA /GEN=MST1R /PROD=macrophage stimulating 1 receptor (c-met-relatedtyrosine kinase) /DB_XREF=gi:4505264 /UG=Hs.2942 macrophage stimulating 1 receptor (c-met-related tyrosine kinase) /FL=gb:NM_002447.1 NM_002447 macrophage stimulating 1 receptor (c-met-related tyrosine kinase) MST1R 4486 NM_001244937 /// NM_002447 /// XM_005265170 /// XR_245136 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0038145 // macrophage colony-stimulating factor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay 0001725 // stress fiber // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005011 // macrophage colony-stimulating factor receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 205456_at NM_000733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000733.1 /DEF=Homo sapiens CD3E antigen, epsilon polypeptide (TiT3 complex) (CD3E), mRNA. /FEA=mRNA /GEN=CD3E /PROD=CD3E antigen, epsilon polypeptide (TiT3complex) /DB_XREF=gi:4502670 /UG=Hs.3003 CD3E antigen, epsilon polypeptide (TiT3 complex) /FL=gb:NM_000733.1 NM_000733 CD3e molecule, epsilon (CD3-TCR complex) CD3E 916 NM_000733 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006461 // protein complex assembly // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042110 // T cell activation // non-traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046649 // lymphocyte activation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001772 // immunological synapse // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay /// 0042101 // T cell receptor complex // non-traceable author statement /// 0042105 // alpha-beta T cell receptor complex // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019901 // protein kinase binding // non-traceable author statement /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0042608 // T cell receptor binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 205457_at NM_024294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024294.1 /DEF=Homo sapiens hypothetical protein MGC4614 (MGC4614), mRNA. /FEA=mRNA /GEN=MGC4614 /PROD=hypothetical protein MGC4614 /DB_XREF=gi:13236513 /UG=Hs.300691 hypothetical protein MGC4614 /FL=gb:BC002328.1 gb:NM_024294.1 NM_024294 chromosome 6 open reading frame 106 C6orf106 64771 NM_022758 /// NM_024294 /// XM_005249298 0005515 // protein binding // inferred from electronic annotation 205458_at BG034972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG034972 /FEA=EST /DB_XREF=gi:12428701 /DB_XREF=est:602325241F1 /CLONE=IMAGE:4413203 /UG=Hs.301240 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) /FL=gb:NM_002386.1 BG034972 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) MC1R 4157 NM_002386 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009650 // UV protection // traceable author statement /// 0010739 // positive regulation of protein kinase A signaling // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070914 // UV-damage excision repair // inferred from direct assay /// 0090037 // positive regulation of protein kinase C signaling // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004980 // melanocyte-stimulating hormone receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008528 // G-protein coupled peptide receptor activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 205459_s_at NM_002518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002518.1 /DEF=Homo sapiens neuronal PAS domain protein 2 (NPAS2), mRNA. /FEA=mRNA /GEN=NPAS2 /PROD=neuronal PAS domain protein 2 /DB_XREF=gi:4505428 /UG=Hs.321164 neuronal PAS domain protein 2 /FL=gb:U77970.1 gb:NM_002518.1 NM_002518 neuronal PAS domain protein 2 NPAS2 4862 NM_002518 /// XM_005263953 /// XM_005263954 /// XM_005263955 /// XM_005263957 /// XM_005263958 /// XM_005263959 /// XM_005263960 /// XM_005263961 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from physical interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 205460_at NM_002518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002518.1 /DEF=Homo sapiens neuronal PAS domain protein 2 (NPAS2), mRNA. /FEA=mRNA /GEN=NPAS2 /PROD=neuronal PAS domain protein 2 /DB_XREF=gi:4505428 /UG=Hs.321164 neuronal PAS domain protein 2 /FL=gb:U77970.1 gb:NM_002518.1 NM_002518 neuronal PAS domain protein 2 NPAS2 4862 NM_002518 /// XM_005263953 /// XM_005263954 /// XM_005263955 /// XM_005263957 /// XM_005263958 /// XM_005263959 /// XM_005263960 /// XM_005263961 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from physical interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 205461_at NM_006861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006861.1 /DEF=Homo sapiens RAB35, member RAS oncogene family (RAB35), mRNA. /FEA=mRNA /GEN=RAB35 /PROD=RAB35, member RAS oncogene family /DB_XREF=gi:5803134 /UG=Hs.331636 RAB35, member RAS oncogene family /FL=gb:NM_006861.1 NM_006861 RAB35, member RAS oncogene family RAB35 11021 NM_001167606 /// NM_006861 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031253 // cell projection membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 205462_s_at NM_002149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002149.1 /DEF=Homo sapiens hippocalcin-like 1 (HPCAL1), mRNA. /FEA=mRNA /GEN=HPCAL1 /PROD=hippocalcin-like 1 /DB_XREF=gi:4504474 /UG=Hs.3618 hippocalcin-like 1 /FL=gb:NM_002149.1 gb:D16227.1 NM_002149 hippocalcin-like 1 HPCAL1 3241 NM_001258357 /// NM_001258358 /// NM_001258359 /// NM_002149 /// NM_134421 /// XM_005246160 /// XM_005246161 /// XM_005246162 /// XM_005246163 /// XM_006711885 /// XR_426955 0007165 // signal transduction // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205463_s_at NM_002607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002607.1 /DEF=Homo sapiens platelet-derived growth factor alpha polypeptide (PDGFA), mRNA. /FEA=mRNA /GEN=PDGFA /PROD=platelet-derived growth factor alphapolypeptide /DB_XREF=gi:4505678 /UG=Hs.37040 platelet-derived growth factor alpha polypeptide /FL=gb:NM_002607.1 NM_002607 platelet-derived growth factor alpha polypeptide PDGFA 5154 NM_002607 /// NM_033023 /// XM_005249770 /// XM_006715733 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009790 // embryo development // traceable author statement /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0030031 // cell projection assembly // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043588 // skin development // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060683 // regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072124 // regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 2000278 // regulation of DNA biosynthetic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005902 // microvillus // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 205464_at NM_000336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000336.1 /DEF=Homo sapiens sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) (SCNN1B), mRNA. /FEA=mRNA /GEN=SCNN1B /PROD=sodium channel, nonvoltage-gated 1, beta /DB_XREF=gi:4506816 /UG=Hs.37129 sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) /FL=gb:NM_000336.1 gb:L36593.1 NM_000336 sodium channel, non-voltage-gated 1, beta subunit SCNN1B 6338 NM_000336 /// XM_005255467 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034706 // sodium channel complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 205465_x_at BF000296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF000296 /FEA=EST /DB_XREF=gi:10700571 /DB_XREF=est:7h25e12.x1 /CLONE=IMAGE:3317038 /UG=Hs.40968 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 /FL=gb:AF019386.1 gb:NM_005114.1 BF000296 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 HS3ST1 9957 NM_005114 /// XM_005248221 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0008146 // sulfotransferase activity // traceable author statement /// 0008467 // [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205466_s_at NM_005114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005114.1 /DEF=Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (HS3ST1), mRNA. /FEA=mRNA /GEN=HS3ST1 /PROD=heparan sulfate D-glucosaminyl3-O-sulfotransferase 1 precursor /DB_XREF=gi:4826763 /UG=Hs.40968 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 /FL=gb:AF019386.1 gb:NM_005114.1 NM_005114 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 HS3ST1 9957 NM_005114 /// XM_005248221 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0008146 // sulfotransferase activity // traceable author statement /// 0008467 // [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205467_at NM_001230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001230.1 /DEF=Homo sapiens caspase 10, apoptosis-related cysteine protease (CASP10), mRNA. /FEA=mRNA /GEN=CASP10 /PROD=caspase 10, apoptosis-related cysteine protease /DB_XREF=gi:4502568 /UG=Hs.5353 caspase 10, apoptosis-related cysteine protease /FL=gb:U60519.1 gb:NM_001230.1 NM_001230 caspase 10, apoptosis-related cysteine peptidase CASP10 843 NM_001206524 /// NM_001206542 /// NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 /// XM_005246907 /// XM_005246909 /// XM_005246910 /// XM_005246911 /// XM_006712796 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0045087 // innate immune response // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0097342 // ripoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 205468_s_at AI028035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI028035 /FEA=EST /DB_XREF=gi:3245344 /DB_XREF=est:oy73d03.x1 /CLONE=IMAGE:1671461 /UG=Hs.54434 interferon regulatory factor 5 /FL=gb:U51127.1 gb:NM_002200.1 AI028035 interferon regulatory factor 5 IRF5 3663 NM_001098627 /// NM_001098629 /// NM_001098630 /// NM_001242452 /// NM_032643 /// XM_005250317 /// XM_006715974 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032494 // response to peptidoglycan // inferred from direct assay /// 0032495 // response to muramyl dipeptide // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred by curator /// 0032728 // positive regulation of interferon-beta production // inferred by curator /// 0032735 // positive regulation of interleukin-12 production // inferred by curator /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205469_s_at NM_002200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002200.1 /DEF=Homo sapiens interferon regulatory factor 5 (IRF5), mRNA. /FEA=mRNA /GEN=IRF5 /PROD=interferon regulatory factor 5 /DB_XREF=gi:4504726 /UG=Hs.54434 interferon regulatory factor 5 /FL=gb:U51127.1 gb:NM_002200.1 NM_002200 interferon regulatory factor 5 IRF5 3663 NM_001098627 /// NM_001098629 /// NM_001098630 /// NM_001242452 /// NM_032643 /// XM_005250317 /// XM_006715974 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032494 // response to peptidoglycan // inferred from direct assay /// 0032495 // response to muramyl dipeptide // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred by curator /// 0032728 // positive regulation of interferon-beta production // inferred by curator /// 0032735 // positive regulation of interleukin-12 production // inferred by curator /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205470_s_at NM_006853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006853.1 /DEF=Homo sapiens kallikrein 11 (KLK11), mRNA. /FEA=mRNA /GEN=KLK11 /PROD=kallikrein 11 /DB_XREF=gi:5803198 /UG=Hs.57771 kallikrein 11 /FL=gb:AB012917.1 gb:NM_006853.1 gb:AB041036.1 NM_006853 kallikrein-related peptidase 11 KLK11 11012 NM_001136032 /// NM_001167605 /// NM_006853 /// NM_144947 /// XM_005258439 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205471_s_at AW772082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW772082 /FEA=EST /DB_XREF=gi:7704144 /DB_XREF=est:hn67b07.x1 /CLONE=IMAGE:3032917 /UG=Hs.63931 dachshund (Drosophila) homolog /FL=gb:NM_004392.1 gb:AF102546.1 AW772082 dachshund family transcription factor 1 DACH1 1602 NM_004392 /// NM_080759 /// NM_080760 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0060244 // negative regulation of cell proliferation involved in contact inhibition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001075 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205472_s_at NM_004392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004392.1 /DEF=Homo sapiens dachshund (Drosophila) homolog (DACH), mRNA. /FEA=mRNA /GEN=DACH /PROD=dachshund (Drosophila) homolog /DB_XREF=gi:4758113 /UG=Hs.63931 dachshund (Drosophila) homolog /FL=gb:NM_004392.1 gb:AF102546.1 NM_004392 dachshund family transcription factor 1 DACH1 1602 NM_004392 /// NM_080759 /// NM_080760 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0060244 // negative regulation of cell proliferation involved in contact inhibition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001075 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205473_at NM_001692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001692.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 1 (ATP6B1), mRNA. /FEA=mRNA /GEN=ATP6B1 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), beta polypeptide, 5658kD, isoform 1 /DB_XREF=gi:4502308 /UG=Hs.64173 ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 1 /FL=gb:M25809.1 gb:NM_001692.1 NM_001692 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 ATP6V1B1 525 NM_001692 /// XM_005264368 0001503 // ossification // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006885 // regulation of pH // inferred from mutant phenotype /// 0007588 // excretion // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from mutant phenotype /// 0033572 // transferrin transport // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0045851 // pH reduction // inferred from mutant phenotype /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055074 // calcium ion homeostasis // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005902 // microvillus // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from mutant phenotype /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005524 // ATP binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 205474_at NM_015986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015986.1 /DEF=Homo sapiens cytokine receptor-like molecule 9 (CREME9), mRNA. /FEA=mRNA /GEN=CREME9 /PROD=cytokine receptor-like molecule 9 /DB_XREF=gi:7705331 /UG=Hs.7120 cytokine receptor-like molecule 9 /FL=gb:AF046059.1 gb:AF120151.1 gb:NM_015986.1 NM_015986 cytokine receptor-like factor 3 CRLF3 51379 NM_015986 /// NR_073118 /// XM_006721941 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 205475_at NM_007281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007281.1 /DEF=Homo sapiens scrapie responsive protein 1 (SCRG1), mRNA. /FEA=mRNA /GEN=SCRG1 /PROD=scrapie responsive protein 1 /DB_XREF=gi:6005869 /UG=Hs.7122 scrapie responsive protein 1 /FL=gb:NM_007281.1 NM_007281 stimulator of chondrogenesis 1 SCRG1 11341 NM_007281 /// XM_006714075 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 205476_at NM_004591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004591.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 20 (SCYA20), mRNA. /FEA=mRNA /GEN=SCYA20 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 20 /DB_XREF=gi:4759075 /UG=Hs.75498 small inducible cytokine subfamily A (Cys-Cys), member 20 /FL=gb:U64197.1 gb:U77035.1 gb:D86955.1 gb:NM_004591.1 NM_004591 chemokine (C-C motif) ligand 20 CCL20 6364 NM_001130046 /// NM_004591 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0042466 // chemokinesis // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation 205477_s_at NM_001633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001633.1 /DEF=Homo sapiens alpha-1-microglobulinbikunin precursor (AMBP), mRNA. /FEA=mRNA /GEN=AMBP /PROD=alpha-1-microglobulinbikunin precursor /DB_XREF=gi:4502066 /UG=Hs.76177 alpha-1-microglobulinbikunin precursor /FL=gb:NM_001633.1 NM_001633 alpha-1-microglobulin/bikunin precursor AMBP 259 NM_001633 0007155 // cell adhesion // non-traceable author statement /// 0007565 // female pregnancy // non-traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0042167 // heme catabolic process // non-traceable author statement /// 0046329 // negative regulation of JNK cascade // traceable author statement /// 0050777 // negative regulation of immune response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019855 // calcium channel inhibitor activity // non-traceable author statement /// 0019862 // IgA binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046904 // calcium oxalate binding // non-traceable author statement 205478_at NM_006741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006741.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 1A (PPP1R1A), mRNA. /FEA=mRNA /GEN=PPP1R1A /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 1A /DB_XREF=gi:5803128 /UG=Hs.76780 protein phosphatase 1, regulatory (inhibitor) subunit 1A /FL=gb:U48707.1 gb:NM_006741.1 NM_006741 protein phosphatase 1, regulatory (inhibitor) subunit 1A PPP1R1A 5502 NM_006741 /// XM_005268995 /// XM_006719471 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205479_s_at NM_002658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002658.1 /DEF=Homo sapiens plasminogen activator, urokinase (PLAU), mRNA. /FEA=mRNA /GEN=PLAU /PROD=plasminogen activator, urokinase /DB_XREF=gi:4505862 /UG=Hs.77274 plasminogen activator, urokinase /FL=gb:M15476.1 gb:NM_002658.1 NM_002658 plasminogen activator, urokinase PLAU 5328 NM_001145031 /// NM_002658 /// XM_006717893 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0061041 // regulation of wound healing // inferred by curator /// 2000097 // regulation of smooth muscle cell-matrix adhesion // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205480_s_at NM_006759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006759.2 /DEF=Homo sapiens UDP-glucose pyrophosphorylase 2 (UGP2), mRNA. /FEA=mRNA /GEN=UGP2 /PROD=UDP-glucose pyrophosphorylase 2 /DB_XREF=gi:13027637 /UG=Hs.77837 UDP-glucose pyrophosphorylase 2 /FL=gb:NM_006759.2 NM_006759 UDP-glucose pyrophosphorylase 2 UGP2 7360 NM_001001521 /// NM_006759 /// XM_005264537 /// XM_005264538 /// XM_006712088 /// XM_006712089 /// XR_426996 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006011 // UDP-glucose metabolic process // inferred from electronic annotation /// 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019255 // glucose 1-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0052695 // cellular glucuronidation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003983 // UTP:glucose-1-phosphate uridylyltransferase activity // not recorded /// 0003983 // UTP:glucose-1-phosphate uridylyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032557 // pyrimidine ribonucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205481_at NM_000674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000674.1 /DEF=Homo sapiens adenosine A1 receptor (ADORA1), mRNA. /FEA=mRNA /GEN=ADORA1 /PROD=adenosine A1 receptor /DB_XREF=gi:4501946 /UG=Hs.77867 adenosine A1 receptor /FL=gb:AB004662.1 gb:S56143.1 gb:L22214.1 gb:NM_000674.1 NM_000674 adenosine A1 receptor ADORA1 134 NM_000674 /// NM_001048230 /// XM_005244899 /// XM_005244901 /// XM_005244902 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0002686 // negative regulation of leukocyte migration // inferred from electronic annotation /// 0002793 // positive regulation of peptide secretion // inferred from electronic annotation /// 0003093 // regulation of glomerular filtration // inferred from electronic annotation /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0006909 // phagocytosis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032244 // positive regulation of nucleoside transport // inferred from electronic annotation /// 0032900 // negative regulation of neurotrophin production // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042323 // negative regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0055118 // negative regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0070256 // negative regulation of mucus secretion // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0032279 // asymmetric synapse // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0001609 // G-protein coupled adenosine receptor activity // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0001883 // purine nucleoside binding // inferred from electronic annotation /// 0004629 // phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0032795 // heterotrimeric G-protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205482_x_at NM_013306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013306.1 /DEF=Homo sapiens sorting nexin 15 (SNX15), mRNA. /FEA=mRNA /GEN=SNX15 /PROD=sorting nexin 15 /DB_XREF=gi:9994182 /UG=Hs.80132 sorting nexin 15 /FL=gb:AF175267.2 gb:AF001435.1 gb:NM_013306.1 NM_013306 sorting nexin 15 SNX15 29907 NM_013306 /// NM_147777 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // non-traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 205483_s_at NM_005101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005101.1 /DEF=Homo sapiens interferon-stimulated protein, 15 kDa (ISG15), mRNA. /FEA=mRNA /GEN=ISG15 /PROD=interferon-stimulated protein, 15 kDa /DB_XREF=gi:4826773 /UG=Hs.833 interferon-stimulated protein, 15 kDa /FL=gb:M13755.1 gb:NM_005101.1 NM_005101 ISG15 ubiquitin-like modifier ISG15 9636 NM_005101 0002376 // immune system process // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032020 // ISG15-protein conjugation // inferred from mutant phenotype /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032649 // regulation of interferon-gamma production // inferred from mutant phenotype /// 0034340 // response to type I interferon // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060337 // type I interferon signaling pathway // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0031386 // protein tag // inferred from electronic annotation 205484_at NM_014450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014450.1 /DEF=Homo sapiens SHP2 interacting transmembrane adaptor (SIT), mRNA. /FEA=mRNA /GEN=SIT /PROD=SHP2 interacting transmembrane adaptor /DB_XREF=gi:7657576 /UG=Hs.88012 SHP2 interacting transmembrane adaptor /FL=gb:NM_014450.1 NM_014450 signaling threshold regulating transmembrane adaptor 1 SIT1 27240 NM_014450 0002376 // immune system process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0050863 // regulation of T cell activation // inferred from direct assay 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0042169 // SH2 domain binding // traceable author statement 205485_at NM_000540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000540.1 /DEF=Homo sapiens ryanodine receptor 1 (skeletal) (RYR1), mRNA. /FEA=mRNA /GEN=RYR1 /PROD=ryanodine receptor 1 (skeletal) /DB_XREF=gi:10863870 /UG=Hs.89631 ryanodine receptor 1 (skeletal) /FL=gb:NM_000540.1 gb:J05200.1 NM_000540 ryanodine receptor 1 (skeletal) RYR1 6261 NM_000540 /// NM_001042723 /// XM_006723317 /// XM_006723318 /// XM_006723319 0001666 // response to hypoxia // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006936 // muscle contraction // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0016485 // protein processing // non-traceable author statement /// 0017157 // regulation of exocytosis // non-traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0019724 // B cell mediated immunity // non-traceable author statement /// 0030100 // regulation of endocytosis // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0031000 // response to caffeine // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0042100 // B cell proliferation // non-traceable author statement /// 0043588 // skin development // inferred from sequence or structural similarity /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005790 // smooth endoplasmic reticulum // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030314 // junctional membrane complex // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031674 // I band // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015278 // calcium-release channel activity // traceable author statement /// 0019899 // enzyme binding // inferred from electronic annotation 205486_at NM_007170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007170.1 /DEF=Homo sapiens testis-specific kinase 2 (TESK2), mRNA. /FEA=mRNA /GEN=TESK2 /PROD=testis-specific protein kinase 2 /DB_XREF=gi:6005895 /UG=Hs.8980 testis-specific kinase 2 /FL=gb:NM_007170.1 NM_007170 testis-specific kinase 2 TESK2 10420 NM_007170 /// XM_005270355 /// XM_006710287 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205487_s_at NM_016267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016267.1 /DEF=Homo sapiens TONDU (TONDU), mRNA. /FEA=mRNA /GEN=TONDU /PROD=TONDU /DB_XREF=gi:7706740 /UG=Hs.9030 TONDU /FL=gb:BC000045.1 gb:AF137387.1 gb:NM_016267.1 NM_016267 vestigial-like family member 1 VGLL1 51442 NM_016267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003713 // transcription coactivator activity // traceable author statement 205488_at NM_006144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006144.2 /DEF=Homo sapiens granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA), mRNA. /FEA=mRNA /GEN=GZMA /PROD=granzyme A precursor /DB_XREF=gi:6996012 /UG=Hs.90708 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) /FL=gb:M18737.1 gb:NM_006144.2 NM_006144 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) GZMA 3001 NM_006144 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019835 // cytolysis // inferred from electronic annotation /// 0032078 // negative regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051354 // negative regulation of oxidoreductase activity // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0001772 // immunological synapse // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 205489_at NM_001888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001888.1 /DEF=Homo sapiens crystallin, mu (CRYM), mRNA. /FEA=mRNA /GEN=CRYM /PROD=crystallin, mu /DB_XREF=gi:4503064 /UG=Hs.924 crystallin, mu /FL=gb:L02950.1 gb:U85772.1 gb:NM_001888.1 NM_001888 crystallin, mu CRYM 1428 NM_001014444 /// NM_001888 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0042403 // thyroid hormone metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070327 // thyroid hormone transport // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047127 // thiomorpholine-carboxylate dehydrogenase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from mutant phenotype 205490_x_at BF060667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF060667 /FEA=EST /DB_XREF=gi:10819565 /DB_XREF=est:7j59a07.x1 /CLONE=IMAGE:3390708 /UG=Hs.98485 gap junction protein, beta 3, 31kD (connexin 31) /FL=gb:NM_024009.1 gb:AF052692.1 BF060667 gap junction protein, beta 3, 31kDa GJB3 2707 NM_001005752 /// NM_024009 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 205491_s_at NM_024009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024009.1 /DEF=Homo sapiens gap junction protein, beta 3, 31kD (connexin 31) (GJB3), mRNA. /FEA=mRNA /GEN=GJB3 /PROD=gap junction protein, beta 3, 31kD (connexin31) /DB_XREF=gi:13128959 /UG=Hs.98485 gap junction protein, beta 3, 31kD (connexin 31) /FL=gb:NM_024009.1 gb:AF052692.1 NM_024009 gap junction protein, beta 3, 31kDa GJB3 2707 NM_001005752 /// NM_024009 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // non-traceable author statement 205492_s_at AW090187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW090187 /FEA=EST /DB_XREF=gi:6047531 /DB_XREF=est:xc92b10.x1 /CLONE=IMAGE:2591707 /UG=Hs.100058 dihydropyrimidinase-like 4 /FL=gb:NM_006426.1 gb:AB006713.1 AW090187 dihydropyrimidinase-like 4 DPYSL4 10570 NM_006426 /// XM_005252658 /// XM_005252659 /// XM_006717547 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 205493_s_at NM_006426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006426.1 /DEF=Homo sapiens dihydropyrimidinase-like 4 (DPYSL4), mRNA. /FEA=mRNA /GEN=DPYSL4 /PROD=dihydropyrimidinase-like 4 /DB_XREF=gi:11321616 /UG=Hs.100058 dihydropyrimidinase-like 4 /FL=gb:NM_006426.1 gb:AB006713.1 NM_006426 dihydropyrimidinase-like 4 DPYSL4 10570 NM_006426 /// XM_005252658 /// XM_005252659 /// XM_006717547 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 205494_at NM_017530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017530.1 /DEF=Homo sapiens hypothetical protein LOC55565 (LOC55565), mRNA. /FEA=mRNA /GEN=LOC55565 /PROD=hypothetical protein LOC55565 /DB_XREF=gi:8922070 /UG=Hs.104788 hypothetical protein LOC55565 /FL=gb:NM_017530.1 NM_017530 zinc finger protein 821 ZNF821 55565 NM_001201552 /// NM_001201553 /// NM_001201554 /// NM_001201556 /// NM_017530 /// XM_005256033 /// XM_005256035 /// XM_006721233 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205495_s_at NM_006433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006433.2 /DEF=Homo sapiens granulysin (GNLY), transcript variant NKG5, mRNA. /FEA=mRNA /GEN=GNLY /PROD=granulysin, isoform NKG5 /DB_XREF=gi:7108343 /UG=Hs.105806 granulysin /FL=gb:NM_006433.2 NM_006433 granulysin GNLY 10578 NM_006433 /// NM_012483 /// XM_005264084 /// XM_005264085 /// XM_005264086 /// XM_005264087 0006968 // cellular defense response // traceable author statement /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 205496_at NM_014702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014702.1 /DEF=Homo sapiens KIAA0408 gene product (KIAA0408), mRNA. /FEA=mRNA /GEN=KIAA0408 /PROD=KIAA0408 gene product /DB_XREF=gi:7662095 /UG=Hs.118744 KIAA0408 gene product /FL=gb:AB007868.1 gb:NM_014702.1 NM_014702 KIAA0408 KIAA0408 9729 NM_014702 0010506 // regulation of autophagy // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205497_at NM_007147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007147.1 /DEF=Homo sapiens zinc finger protein 175 (ZNF175), mRNA. /FEA=mRNA /GEN=ZNF175 /PROD=zinc finger protein 175 /DB_XREF=gi:6005969 /UG=Hs.119014 zinc finger protein 175 /FL=gb:D50419.1 gb:NM_007147.1 NM_007147 zinc finger protein 175 ZNF175 7728 NM_007147 /// XM_005259216 /// XM_005259217 /// XM_005259218 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205498_at NM_000163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000163.1 /DEF=Homo sapiens growth hormone receptor (GHR), mRNA. /FEA=mRNA /GEN=GHR /PROD=growth hormone receptor /DB_XREF=gi:4503992 /UG=Hs.125180 growth hormone receptor /FL=gb:NM_000163.1 NM_000163 growth hormone receptor GHR 2690 NM_000163 /// NM_001242399 /// NM_001242400 /// NM_001242401 /// NM_001242402 /// NM_001242403 /// NM_001242404 /// NM_001242405 /// NM_001242406 /// NM_001242460 /// NM_001242461 /// NM_001242462 /// XM_005248288 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0031623 // receptor internalization // inferred from direct assay /// 0032094 // response to food // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042976 // activation of Janus kinase activity // inferred from electronic annotation /// 0042977 // activation of JAK2 kinase activity // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044236 // multicellular organismal metabolic process // inferred from mutant phenotype /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046898 // response to cycloheximide // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from mutant phenotype /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070195 // growth hormone receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004903 // growth hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from sequence or structural similarity 205499_at NM_014467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014467.1 /DEF=Homo sapiens sushi-repeat protein (SRPUL), mRNA. /FEA=mRNA /GEN=SRPUL /PROD=sushi-repeat protein /DB_XREF=gi:7657618 /UG=Hs.126782 sushi-repeat protein /FL=gb:AF060567.1 gb:NM_014467.1 NM_014467 sushi-repeat containing protein, X-linked 2 SRPX2 27286 NM_014467 /// XM_005262121 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0048870 // cell motility // inferred from direct assay /// 0051965 // positive regulation of synapse assembly // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0036458 // hepatocyte growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay 205500_at NM_001735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001735.1 /DEF=Homo sapiens complement component 5 (C5), mRNA. /FEA=mRNA /GEN=C5 /PROD=complement component 5 /DB_XREF=gi:4502506 /UG=Hs.1281 complement component 5 /FL=gb:M57729.1 gb:NM_001735.1 NM_001735 complement component 5 C5 727 NM_001735 0000187 // activation of MAPK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0010760 // negative regulation of macrophage chemotaxis // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0090197 // positive regulation of chemokine secretion // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // traceable author statement /// 0031714 // C5a anaphylatoxin chemotactic receptor binding // inferred from electronic annotation 205501_at AI143879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI143879 /FEA=EST /DB_XREF=gi:3665688 /DB_XREF=est:qe04f11.x1 /CLONE=IMAGE:1738029 /UG=Hs.128291 phosphodiesterase 10A /FL=gb:AF127479.1 gb:AB020593.1 gb:NM_006661.1 AI143879 phosphodiesterase 10A PDE10A 10846 NM_001130690 /// NM_006661 /// NR_045597 /// XM_006715321 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from direct assay /// 0030552 // cAMP binding // non-traceable author statement /// 0030553 // cGMP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 205502_at NM_000102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000102.1 /DEF=Homo sapiens cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia (CYP17), mRNA. /FEA=mRNA /GEN=CYP17 /PROD=cytochrome P450, subfamily XVII (steroid17-alpha-hydroxylase), adrenal hyperplasia /DB_XREF=gi:4503194 /UG=Hs.1363 cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia /FL=gb:M14564.1 gb:NM_000102.1 NM_000102 cytochrome P450, family 17, subfamily A, polypeptide 1 CYP17A1 1586 NM_000102 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006702 // androgen biosynthetic process // traceable author statement /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007548 // sex differentiation // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010034 // response to acetate // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0017085 // response to insecticide // inferred from electronic annotation /// 0018879 // biphenyl metabolic process // inferred from electronic annotation /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0018958 // phenol-containing compound metabolic process // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004508 // steroid 17-alpha-monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047442 // 17-alpha-hydroxyprogesterone aldolase activity // inferred from electronic annotation 205503_at NM_005401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005401.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 14 (PTPN14), mRNA. /FEA=mRNA /GEN=PTPN14 /PROD=protein tyrosine phosphatase, non-receptor type14 /DB_XREF=gi:4885566 /UG=Hs.159238 protein tyrosine phosphatase, non-receptor type 14 /FL=gb:NM_005401.1 NM_005401 protein tyrosine phosphatase, non-receptor type 14 PTPN14 5784 NM_005401 /// XR_247032 0001946 // lymphangiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0046825 // regulation of protein export from nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from mutant phenotype /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 205504_at NM_000061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000061.1 /DEF=Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), mRNA. /FEA=mRNA /GEN=BTK /PROD=Bruton agammaglobulinemia tyrosine kinase /DB_XREF=gi:4557376 /UG=Hs.159494 Bruton agammaglobulinemia tyrosine kinase /FL=gb:NM_000061.1 gb:AF153756.1 gb:AF153757.1 gb:AF153758.1 gb:AF153759.1 gb:AF153760.1 gb:AF153761.1 gb:AF153762.1 gb:AF153364.1 NM_000061 Bruton agammaglobulinemia tyrosine kinase BTK 695 NM_000061 /// NM_001287344 /// NM_001287345 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002721 // regulation of B cell cytokine production // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002902 // regulation of B cell apoptotic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045579 // positive regulation of B cell differentiation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205505_at NM_001490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001490.1 /DEF=Homo sapiens glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) (GCNT1), mRNA. /FEA=mRNA /GEN=GCNT1 /PROD=beta-1,3-galactosyl-O-glycosyl-glycoproteinbeta-1,6-N-acetylglucosaminyltransferase /DB_XREF=gi:4503960 /UG=Hs.159642 glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) /FL=gb:M97347.1 gb:NM_001490.1 NM_001490 glucosaminyl (N-acetyl) transferase 1, core 2 GCNT1 2650 NM_001097633 /// NM_001097634 /// NM_001097635 /// NM_001097636 /// NM_001490 /// XM_006717052 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from mutant phenotype /// 0016266 // O-glycan processing // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0050901 // leukocyte tethering or rolling // inferred from mutant phenotype /// 0060352 // cell adhesion molecule production // inferred from mutant phenotype /// 0060993 // kidney morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from direct assay 0003829 // beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 205506_at NM_007127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007127.1 /DEF=Homo sapiens villin 1 (VIL1), mRNA. /FEA=mRNA /GEN=VIL1 /PROD=villin 1 /DB_XREF=gi:6005943 /UG=Hs.166068 villin 1 /FL=gb:NM_007127.1 NM_007127 villin 1 VIL1 7429 NM_007127 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009617 // response to bacterium // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0051014 // actin filament severing // inferred from direct assay /// 0051125 // regulation of actin nucleation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from direct assay /// 0060327 // cytoplasmic actin-based contraction involved in cell motility // inferred from direct assay /// 0061041 // regulation of wound healing // inferred from sequence or structural similarity /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 2000392 // regulation of lamellipodium morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0032432 // actin filament bundle // inferred from direct assay /// 0032433 // filopodium tip // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035727 // lysophosphatidic acid binding // inferred from direct assay /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay 205507_at NM_014958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014958.1 /DEF=Homo sapiens KIAA0915 protein (KIAA0915), mRNA. /FEA=mRNA /GEN=KIAA0915 /PROD=KIAA0915 protein /DB_XREF=gi:7662377 /UG=Hs.16714 Rho guanine exchange factor (GEF) 15 /FL=gb:AB020722.1 gb:NM_014958.1 NM_014958 Rho guanine nucleotide exchange factor (GEF) 15 ARHGEF15 22899 NM_025014 /// NM_173728 /// XM_005256537 /// XM_006721474 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 2000297 // negative regulation of synapse maturation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205508_at NM_001037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001037.1 /DEF=Homo sapiens sodium channel, voltage-gated, type I, beta polypeptide (SCN1B), mRNA. /FEA=mRNA /GEN=SCN1B /PROD=sodium channel, voltage-gated, type I, betapolypeptide /DB_XREF=gi:4506804 /UG=Hs.170238 sodium channel, voltage-gated, type I, beta polypeptide /FL=gb:L10338.1 gb:L16242.1 gb:NM_001037.1 NM_001037 sodium channel, voltage-gated, type I, beta subunit SCN1B 6324 NM_001037 /// NM_199037 /// XM_005259144 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019227 // neuronal action potential propagation // inferred from sequence or structural similarity /// 0021966 // corticospinal neuron axon guidance // inferred from sequence or structural similarity /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0040011 // locomotion // inferred from sequence or structural similarity /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from direct assay /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from sequence or structural similarity /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0061337 // cardiac conduction // inferred from sequence or structural similarity /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086047 // membrane depolarization during Purkinje myocyte cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0034706 // sodium channel complex // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0019871 // sodium channel inhibitor activity // inferred from sequence or structural similarity /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype /// 0086062 // voltage-gated sodium channel activity involved in Purkinje myocyte action potential // inferred from mutant phenotype 205509_at NM_001871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001871.1 /DEF=Homo sapiens carboxypeptidase B1 (tissue) (CPB1), mRNA. /FEA=mRNA /GEN=CPB1 /PROD=pancreatic carboxypeptidase B1 precursor /DB_XREF=gi:4503002 /UG=Hs.180884 carboxypeptidase B1 (tissue) /FL=gb:NM_001871.1 gb:M81057.1 NM_001871 carboxypeptidase B1 (tissue) CPB1 1360 NM_001871 /// XM_005247124 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205510_s_at NM_017976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017976.1 /DEF=Homo sapiens hypothetical protein FLJ10038 (FLJ10038), mRNA. /FEA=mRNA /GEN=FLJ10038 /PROD=hypothetical protein FLJ10038 /DB_XREF=gi:8922197 /UG=Hs.181202 hypothetical protein FLJ10038 /FL=gb:NM_017976.1 NM_017976 uncharacterized protein FLJ10038 FLJ10038 55056 NM_017976 /// NR_026891 205511_at NM_017976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017976.1 /DEF=Homo sapiens hypothetical protein FLJ10038 (FLJ10038), mRNA. /FEA=mRNA /GEN=FLJ10038 /PROD=hypothetical protein FLJ10038 /DB_XREF=gi:8922197 /UG=Hs.181202 hypothetical protein FLJ10038 /FL=gb:NM_017976.1 NM_017976 uncharacterized protein FLJ10038 FLJ10038 55056 NM_017976 /// NR_026891 205512_s_at NM_004208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004208.1 /DEF=Homo sapiens programmed cell death 8 (apoptosis-inducing factor) (PDCD8), mRNA. /FEA=mRNA /GEN=PDCD8 /PROD=programmed cell death 8 (apoptosis-inducingfactor) /DB_XREF=gi:4757731 /UG=Hs.18720 programmed cell death 8 (apoptosis-inducing factor) /FL=gb:AF100928.1 gb:NM_004208.1 NM_004208 apoptosis-inducing factor, mitochondrion-associated, 1 AIFM1 9131 NM_001130846 /// NM_001130847 /// NM_004208 /// NM_145812 /// NM_145813 0006308 // DNA catabolic process // traceable author statement /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from direct assay /// 0030261 // chromosome condensation // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from mutant phenotype /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016174 // NAD(P)H oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 205513_at NM_001062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001062.1 /DEF=Homo sapiens transcobalamin I (vitamin B12 binding protein, R binder family) (TCN1), mRNA. /FEA=mRNA /GEN=TCN1 /PROD=transcobalamin I (vitamin B12 binding protein, Rbinder family) /DB_XREF=gi:4507406 /UG=Hs.2012 transcobalamin I (vitamin B12 binding protein, R binder family) /FL=gb:J05068.1 gb:NM_001062.1 NM_001062 transcobalamin I (vitamin B12 binding protein, R binder family) TCN1 6947 NM_001062 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // not recorded /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0031419 // cobalamin binding // not recorded 205514_at NM_018355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018355.1 /DEF=Homo sapiens hypothetical protein FLJ11191 (FLJ11191), mRNA. /FEA=mRNA /GEN=FLJ11191 /PROD=hypothetical protein FLJ11191 /DB_XREF=gi:8922928 /UG=Hs.21838 hypothetical protein FLJ11191 /FL=gb:NM_018355.1 NM_018355 zinc finger protein 415 ZNF415 55786 NM_001136038 /// NM_001164309 /// NM_018355 /// NR_028343 /// XM_006723267 /// XM_006723268 /// XM_006723269 /// XM_006723270 /// XM_006723271 /// XM_006723272 /// XM_006723273 /// XM_006723274 /// XM_006723275 /// XM_006723276 /// XM_006723277 /// XM_006723278 /// XM_006723279 /// XM_006723280 /// XM_006723281 /// XM_006723282 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205515_at NM_003619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003619.1 /DEF=Homo sapiens protease, serine, 12 (neurotrypsin, motopsin) (PRSS12), mRNA. /FEA=mRNA /GEN=PRSS12 /PROD=protease, serine, 12 (neurotrypsin, motopsin) /DB_XREF=gi:4506142 /UG=Hs.22404 protease, serine, 12 (neurotrypsin, motopsin) /FL=gb:NM_003619.1 NM_003619 protease, serine, 12 (neurotrypsin, motopsin) PRSS12 8492 NM_003619 /// XM_005263318 0006508 // proteolysis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0031638 // zymogen activation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043083 // synaptic cleft // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205516_x_at NM_012127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012127.1 /DEF=Homo sapiens Cip1-interacting zinc finger protein (CIZ1), mRNA. /FEA=mRNA /GEN=CIZ1 /PROD=Cip1-interacting zinc finger protein /DB_XREF=gi:6912307 /UG=Hs.23476 Cip1-interacting zinc finger protein /FL=gb:AB030835.1 gb:AF159025.1 gb:NM_012127.1 NM_012127 CDKN1A interacting zinc finger protein 1 CIZ1 25792 NM_001131015 /// NM_001131016 /// NM_001131017 /// NM_001131018 /// NM_001257975 /// NM_001257976 /// NM_012127 /// XM_005251886 /// XM_005251887 /// XM_005251888 /// XM_005251889 /// XM_005251890 /// XM_005251891 /// XM_005251892 /// XM_005251893 /// XM_006717036 /// XM_006717037 /// XM_006717038 /// XM_006717039 /// XM_006717040 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from electronic annotation /// 0051658 // maintenance of nucleus location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205517_at AV700724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700724 /FEA=EST /DB_XREF=gi:10302695 /DB_XREF=est:AV700724 /CLONE=GKCGDA03 /UG=Hs.243987 GATA-binding protein 4 /FL=gb:D78260.1 gb:NM_002052.1 gb:L34357.1 AV700724 GATA binding protein 4 GATA4 2626 NM_002052 /// XM_005272384 /// XM_005272385 /// XM_005272386 /// XM_006716248 /// XM_006716249 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from mutant phenotype /// 0003197 // endocardial cushion development // inferred from sequence or structural similarity /// 0003208 // cardiac ventricle morphogenesis // traceable author statement /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003290 // atrial septum secundum morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007492 // endoderm development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035054 // embryonic heart tube anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051891 // positive regulation of cardioblast differentiation // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060008 // Sertoli cell differentiation // inferred from electronic annotation /// 0060043 // regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060464 // lung lobe formation // inferred from electronic annotation /// 0060575 // intestinal epithelial cell differentiation // inferred from direct assay /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0072148 // epithelial cell fate commitment // inferred from electronic annotation /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction 205518_s_at NM_003570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003570.1 /DEF=Homo sapiens cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) (CMAH), mRNA. /FEA=mRNA /GEN=CMAH /PROD=cytidine monophospho-N-acetylneuraminic acidhydroxylase /DB_XREF=gi:4502908 /UG=Hs.24697 cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) /FL=gb:BC003406.1 gb:D86324.1 gb:NM_003570.1 NM_003570 cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene CMAHP 8418 NR_002174 /// NR_027626 0046381 // CMP-N-acetylneuraminate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030338 // CMP-N-acetylneuraminate monooxygenase activity // non-traceable author statement /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 205519_at NM_024908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024908.1 /DEF=Homo sapiens hypothetical protein FLJ12973 (FLJ12973), mRNA. /FEA=mRNA /GEN=FLJ12973 /PROD=hypothetical protein FLJ12973 /DB_XREF=gi:13376366 /UG=Hs.250154 hypothetical protein FLJ12973 /FL=gb:NM_024908.1 NM_024908 WD repeat domain 76 WDR76 79968 NM_001167941 /// NM_024908 /// XM_005254680 /// XM_005254681 0005515 // protein binding // inferred from electronic annotation 205520_at NM_003162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003162.1 /DEF=Homo sapiens striatin, calmodulin-binding protein (STRN), mRNA. /FEA=mRNA /GEN=STRN /PROD=striatin, calmodulin-binding protein /DB_XREF=gi:4507282 /UG=Hs.258538 striatin, calmodulin-binding protein /FL=gb:NM_003162.1 NM_003162 striatin, calmodulin binding protein STRN 6801 NM_003162 /// XM_005264519 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // non-traceable author statement /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 205521_at BF511976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511976 /FEA=EST /DB_XREF=gi:11595274 /DB_XREF=est:UI-H-BI4-apu-a-03-0-UI.s1 /CLONE=IMAGE:3088420 /UG=Hs.266258 endonuclease G-like 1 /FL=gb:AB020523.1 gb:NM_005107.1 BF511976 endo/exonuclease (5'-3'), endonuclease G-like EXOG 9941 NM_001145464 /// NM_005107 /// XM_005265633 /// XM_005265635 /// XM_006713442 /// XM_006713443 /// XM_006713444 /// XM_006713445 /// XM_006713446 /// XM_006713447 0000737 // DNA catabolic process, endonucleolytic // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205522_at NM_014621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014621.1 /DEF=Homo sapiens homeo box D4 (HOXD4), mRNA. /FEA=mRNA /GEN=HOXD4 /PROD=homeo box D4 /DB_XREF=gi:11024701 /UG=Hs.278255 homeo box D4 /FL=gb:NM_014621.1 NM_014621 205523_at U43328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43328.1 /DEF=Human link protein mRNA, complete cds. /FEA=mRNA /PROD=link protein /DB_XREF=gi:1151008 /UG=Hs.2799 cartilage linking protein 1 /FL=gb:U43328.1 gb:NM_001884.1 U43328 hyaluronan and proteoglycan link protein 1 HAPLN1 1404 NM_001884 0007155 // cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation 205524_s_at NM_001884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001884.1 /DEF=Homo sapiens cartilage linking protein 1 (CRTL1), mRNA. /FEA=mRNA /GEN=CRTL1 /PROD=cartilage linking protein 1 /DB_XREF=gi:4503052 /UG=Hs.2799 cartilage linking protein 1 /FL=gb:U43328.1 gb:NM_001884.1 NM_001884 hyaluronan and proteoglycan link protein 1 HAPLN1 1404 NM_001884 0007155 // cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation 205525_at NM_018495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018495.3 /DEF=Homo sapiens NAG22 protein (LOC55873), mRNA. /FEA=mRNA /GEN=LOC55873 /PROD=NAG22 protein /DB_XREF=gi:13236500 /UG=Hs.283080 NAG22 protein /FL=gb:AF247820.3 gb:NM_018495.3 NM_018495 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 205526_s_at NM_007044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007044.2 /DEF=Homo sapiens katanin p60 (ATPase-containing) subunit A 1 (KATNA1), mRNA. /FEA=mRNA /GEN=KATNA1 /PROD=katanin p60 subunit A 1 /DB_XREF=gi:9951918 /UG=Hs.289099 katanin p60 (ATPase-containing) subunit A 1 /FL=gb:NM_007044.2 NM_007044 katanin p60 (ATPase containing) subunit A 1 KATNA1 11104 NM_001204076 /// NM_007044 /// XM_005266804 /// XM_005266805 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0051013 // microtubule severing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051329 // mitotic interphase // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 205527_s_at NM_015487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015487.1 /DEF=Homo sapiens DKFZP434D174 protein (DKFZP434D174), mRNA. /FEA=mRNA /GEN=DKFZP434D174 /PROD=DKFZP434D174 protein /DB_XREF=gi:11094402 /UG=Hs.302421 DKFZP434D174 protein /FL=gb:NM_015487.1 NM_015487 gem (nuclear organelle) associated protein 4 GEMIN4 50628 NM_015721 /// XM_005256667 /// XM_005256668 /// XM_005256670 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205528_s_at X79990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79990.1 /DEF=H.sapiens ETO mRNA. /FEA=mRNA /GEN=ETO /DB_XREF=gi:510523 /UG=Hs.31551 core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related /FL=gb:NM_004349.1 gb:D43638.1 X79990 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) RUNX1T1 862 NM_001198625 /// NM_001198626 /// NM_001198627 /// NM_001198628 /// NM_001198629 /// NM_001198630 /// NM_001198631 /// NM_001198632 /// NM_001198633 /// NM_001198634 /// NM_001198679 /// NM_004349 /// NM_175634 /// NM_175635 /// NM_175636 /// XM_006716676 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0051101 // regulation of DNA binding // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 205529_s_at NM_004349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004349.1 /DEF=Homo sapiens core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related (CBFA2T1), mRNA. /FEA=mRNA /GEN=CBFA2T1 /PROD=core-binding factor, runt domain, alpha subunit2; translocated to, 1; cyclin D-related /DB_XREF=gi:4757915 /UG=Hs.31551 core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related /FL=gb:NM_004349.1 gb:D43638.1 NM_004349 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) RUNX1T1 862 NM_001198625 /// NM_001198626 /// NM_001198627 /// NM_001198628 /// NM_001198629 /// NM_001198630 /// NM_001198631 /// NM_001198632 /// NM_001198633 /// NM_001198634 /// NM_001198679 /// NM_004349 /// NM_175634 /// NM_175635 /// NM_175636 /// XM_006716676 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0051101 // regulation of DNA binding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205530_at NM_004453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004453.1 /DEF=Homo sapiens electron-transferring-flavoprotein dehydrogenase (ETFDH), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ETFDH /PROD=electron-transferring-flavoproteindehydrogenase /DB_XREF=gi:4758311 /UG=Hs.323468 electron-transferring-flavoprotein dehydrogenase /FL=gb:NM_004453.1 NM_004453 electron-transferring-flavoprotein dehydrogenase ETFDH 2110 NM_001281737 /// NM_001281738 /// NM_004453 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0022900 // electron transport chain // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay 0004174 // electron-transferring-flavoprotein dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0043783 // oxidoreductase activity, oxidizing metal ions with flavin as acceptor // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from direct assay /// 0048039 // ubiquinone binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 205531_s_at NM_013267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013267.1 /DEF=Homo sapiens breast cell glutaminase (GA), mRNA. /FEA=mRNA /GEN=GA /PROD=breast cell glutaminase /DB_XREF=gi:7019388 /UG=Hs.325443 breast cell glutaminase /FL=gb:AF110330.1 gb:AF110331.1 gb:AF223944.1 gb:NM_013267.1 NM_013267 glutaminase 2 (liver, mitochondrial) GLS2 27165 NM_001280796 /// NM_001280797 /// NM_001280798 /// NM_013267 /// NM_138566 /// XM_005268797 /// XM_005268798 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0004359 // glutaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 205532_s_at AU151483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151483 /FEA=EST /DB_XREF=gi:11013004 /DB_XREF=est:AU151483 /CLONE=NT2RP2005327 /UG=Hs.32963 cadherin 6, type 2, K-cadherin (fetal kidney) /FL=gb:NM_004932.1 gb:D31784.1 AU151483 cadherin 6, type 2, K-cadherin (fetal kidney) CDH6 1004 NM_004932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205533_s_at NM_004932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004932.1 /DEF=Homo sapiens cadherin 6, type 2, K-cadherin (fetal kidney) (CDH6), mRNA. /FEA=mRNA /GEN=CDH6 /PROD=cadherin 6, type 2, K-cadherin (fetal kidney) /DB_XREF=gi:4826672 /UG=Hs.32963 cadherin 6, type 2, K-cadherin (fetal kidney) /FL=gb:NM_004932.1 gb:D31784.1 NM_004932 cadherin 6, type 2, K-cadherin (fetal kidney) CDH6 1004 NM_004932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205534_at NM_002589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002589.1 /DEF=Homo sapiens BH-protocadherin (brain-heart) (PCDH7), mRNA. /FEA=mRNA /GEN=PCDH7 /PROD=BH-protocadherin (brain-heart) /DB_XREF=gi:4505634 /UG=Hs.34073 BH-protocadherin (brain-heart) /FL=gb:AB006755.1 gb:NM_002589.1 NM_002589 protocadherin 7 PCDH7 5099 NM_001173523 /// NM_002589 /// NM_032456 /// NM_032457 /// XM_005248163 /// XM_005248164 /// XM_005248165 /// XM_005248166 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 205535_s_at NM_002589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002589.1 /DEF=Homo sapiens BH-protocadherin (brain-heart) (PCDH7), mRNA. /FEA=mRNA /GEN=PCDH7 /PROD=BH-protocadherin (brain-heart) /DB_XREF=gi:4505634 /UG=Hs.34073 BH-protocadherin (brain-heart) /FL=gb:AB006755.1 gb:NM_002589.1 NM_002589 protocadherin 7 PCDH7 5099 NM_001173523 /// NM_002589 /// NM_032456 /// NM_032457 /// XM_005248163 /// XM_005248164 /// XM_005248165 /// XM_005248166 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205536_at NM_003371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003371.1 /DEF=Homo sapiens vav 2 oncogene (VAV2), mRNA. /FEA=mRNA /GEN=VAV2 /PROD=vav 2 oncogene /DB_XREF=gi:4507870 /UG=Hs.4248 vav 2 oncogene /FL=gb:NM_003371.1 NM_003371 vav 2 guanine nucleotide exchange factor VAV2 7410 NM_001134398 /// NM_003371 /// XM_005272213 /// XM_006717277 0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016477 // cell migration // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // not recorded /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205537_s_at NM_003371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003371.1 /DEF=Homo sapiens vav 2 oncogene (VAV2), mRNA. /FEA=mRNA /GEN=VAV2 /PROD=vav 2 oncogene /DB_XREF=gi:4507870 /UG=Hs.4248 vav 2 oncogene /FL=gb:NM_003371.1 NM_003371 vav 2 guanine nucleotide exchange factor VAV2 7410 NM_001134398 /// NM_003371 /// XM_005272213 /// XM_006717277 0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016477 // cell migration // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // not recorded /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205538_at NM_003389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003389.1 /DEF=Homo sapiens coronin, actin-binding protein, 2A (CORO2A), mRNA. /FEA=mRNA /GEN=CORO2A /PROD=coronin, actin-binding protein, 2A /DB_XREF=gi:4507914 /UG=Hs.44396 coronin, actin-binding protein, 2A /FL=gb:BC000010.1 gb:NM_003389.1 NM_003389 coronin, actin binding protein, 2A CORO2A 7464 NM_003389 /// NM_052820 0030036 // actin cytoskeleton organization // not recorded /// 0035556 // intracellular signal transduction // traceable author statement 0015629 // actin cytoskeleton // not recorded /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0051015 // actin filament binding // not recorded 205539_at NM_006576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006576.1 /DEF=Homo sapiens advillin (AVIL), mRNA. /FEA=mRNA /GEN=AVIL /PROD=advillin /DB_XREF=gi:5729735 /UG=Hs.47344 advillin /FL=gb:AF041449.1 gb:NM_006576.1 NM_006576 advillin AVIL 10677 NM_006576 /// XM_006719198 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity 0003779 // actin binding // inferred from sequence or structural similarity 205540_s_at NM_016656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016656.1 /DEF=Homo sapiens GTP-binding protein ragB (RAGB), transcript variant RAGBl, mRNA. /FEA=mRNA /GEN=RAGB /PROD=GTP-binding protein ragB long isoform /DB_XREF=gi:8051626 /UG=Hs.50282 GTP-binding protein ragB /FL=gb:NM_016656.1 NM_016656 Ras-related GTP binding B RRAGB 10325 NM_006064 /// NM_016656 /// XM_005261973 /// XM_005261974 /// XM_005261975 /// XR_244464 /// XR_244465 /// XR_430513 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0032561 // guanyl ribonucleotide binding // inferred from direct assay 205541_s_at NM_018094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018094.1 /DEF=Homo sapiens hypothetical protein FLJ10441 (FLJ10441), mRNA. /FEA=mRNA /GEN=FLJ10441 /PROD=hypothetical protein FLJ10441 /DB_XREF=gi:8922423 /UG=Hs.59523 hypothetical protein FLJ10441 /FL=gb:NM_018094.1 NM_018094 G1 to S phase transition 2 GSPT2 23708 NM_018094 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205542_at NM_012449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012449.1 /DEF=Homo sapiens six transmembrane epithelial antigen of the prostate (STEAP), mRNA. /FEA=mRNA /GEN=STEAP /PROD=six transmembrane epithelial antigen of theprostate /DB_XREF=gi:9558758 /UG=Hs.61635 six transmembrane epithelial antigen of the prostate /FL=gb:AF186249.1 gb:NM_012449.1 NM_012449 six transmembrane epithelial antigen of the prostate 1 STEAP1 26872 NM_012449 0006811 // ion transport // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0015267 // channel activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205543_at NM_014278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014278.1 /DEF=Homo sapiens heat shock protein (hsp110 family) (APG-1), mRNA. /FEA=mRNA /GEN=APG-1 /PROD=heat shock protein (hsp110 family) /DB_XREF=gi:7656893 /UG=Hs.71992 heat shock protein (hsp110 family) /FL=gb:AB023421.1 gb:NM_014278.1 NM_014278 heat shock 70kDa protein 4-like HSPA4L 22824 NM_014278 /// XM_006714140 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity 205544_s_at NM_001877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001877.1 /DEF=Homo sapiens complement component (3dEpstein Barr virus) receptor 2 (CR2), mRNA. /FEA=mRNA /GEN=CR2 /PROD=complement component (3dEpstein Barr virus)receptor 2 /DB_XREF=gi:4503026 /UG=Hs.73792 complement component (3dEpstein Barr virus) receptor 2 /FL=gb:M26004.1 gb:NM_001877.1 NM_001877 complement component (3d/Epstein Barr virus) receptor 2 CR2 1380 NM_001006658 /// NM_001877 0002376 // immune system process // inferred from electronic annotation /// 0002430 // complement receptor mediated signaling pathway // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0004875 // complement receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 205545_x_at NM_014280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014280.1 /DEF=Homo sapiens splicing factor similar to dnaJ (SPF31), mRNA. /FEA=mRNA /GEN=SPF31 /PROD=splicing factor similar to dnaJ /DB_XREF=gi:7657610 /UG=Hs.74711 DnaJ (Hsp40) homolog, subfamily C, member 8 /FL=gb:AF083190.1 gb:NM_014280.1 NM_014280 DnaJ (Hsp40) homolog, subfamily C, member 8 DNAJC8 22826 NM_014280 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005654 // nucleoplasm // traceable author statement 205546_s_at NM_003331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003331.1 /DEF=Homo sapiens tyrosine kinase 2 (TYK2), mRNA. /FEA=mRNA /GEN=TYK2 /PROD=tyrosine kinase 2 /DB_XREF=gi:4507748 /UG=Hs.75516 tyrosine kinase 2 /FL=gb:NM_003331.1 NM_003331 tyrosine kinase 2 TYK2 7297 NM_003331 0006468 // protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 205547_s_at NM_003186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003186.2 /DEF=Homo sapiens transgelin (TAGLN), mRNA. /FEA=mRNA /GEN=TAGLN /PROD=transgelin /DB_XREF=gi:12621918 /UG=Hs.75777 transgelin /FL=gb:NM_003186.2 gb:M95787.1 gb:D17409.1 NM_003186 transgelin TAGLN 6876 NM_001001522 /// NM_003186 0007517 // muscle organ development // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205548_s_at NM_006806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006806.1 /DEF=Homo sapiens BTG family, member 3 (BTG3), mRNA. /FEA=mRNA /GEN=BTG3 /PROD=BTG family, member 3 /DB_XREF=gi:5802989 /UG=Hs.77311 BTG family, member 3 /FL=gb:D64110.1 gb:NM_006806.1 NM_006806 BTG family, member 3 BTG3 10950 NM_001130914 /// NM_006806 /// XM_006723963 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205549_at NM_006198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006198.1 /DEF=Homo sapiens Purkinje cell protein 4 (PCP4), mRNA. /FEA=mRNA /GEN=PCP4 /PROD=Purkinje cell protein 4 /DB_XREF=gi:5453857 /UG=Hs.80296 Purkinje cell protein 4 /FL=gb:U52969.1 gb:NM_006198.1 NM_006198 Purkinje cell protein 4 PCP4 5121 NM_006198 0007417 // central nervous system development // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005516 // calmodulin binding // inferred from electronic annotation 205550_s_at NM_004899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004899.1 /DEF=Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), mRNA. /FEA=mRNA /GEN=BRE /PROD=brain and reproductive organ-expressed (TNFRSF1Amodulator) /DB_XREF=gi:4757871 /UG=Hs.80426 brain and reproductive organ-expressed (TNFRSF1A modulator) /FL=gb:BC001251.1 gb:NM_004899.1 gb:L38616.1 NM_004899 brain and reproductive organ-expressed (TNFRSF1A modulator) BRE 9577 NM_001261840 /// NM_004899 /// NM_199191 /// NM_199192 /// NM_199193 /// NM_199194 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype 0000152 // nuclear ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 205551_at NM_014848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014848.1 /DEF=Homo sapiens KIAA0735 gene product; synaptic vesicle protein 2B homolog (KIAA0735), mRNA. /FEA=mRNA /GEN=KIAA0735 /PROD=KIAA0735 gene product; synaptic vesicle protein2B homolog /DB_XREF=gi:7662269 /UG=Hs.8071 KIAA0735 gene product; synaptic vesicle protein 2B homolog /FL=gb:AB018278.1 gb:NM_014848.1 NM_014848 synaptic vesicle glycoprotein 2B SV2B 9899 NM_001167580 /// NM_014848 /// XM_005254997 /// XM_005254998 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 205552_s_at NM_002534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002534.1 /DEF=Homo sapiens 2,5-oligoadenylate synthetase 1 (40-46 kD) (OAS1), transcript variant E16, mRNA. /FEA=mRNA /GEN=OAS1 /PROD=2,5-oligoadenylate synthetase 1, isoform E16 /DB_XREF=gi:8051622 /UG=Hs.82396 2,5-oligoadenylate synthetase 1 (40-46 kD) /FL=gb:BC000562.1 gb:D00068.1 gb:NM_002534.1 NM_002534 2'-5'-oligoadenylate synthetase 1, 40/46kDa OAS1 4938 NM_001032409 /// NM_002534 /// NM_016816 /// XM_006719434 0002376 // immune system process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006164 // purine nucleotide biosynthetic process // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060700 // regulation of ribonuclease activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205553_s_at NM_003476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003476.1 /DEF=Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3), mRNA. /FEA=mRNA /GEN=CSRP3 /PROD=cysteine and glycine-rich protein 3 /DB_XREF=gi:4502892 /UG=Hs.83577 cysteine and glycine-rich protein 3 (cardiac LIM protein) /FL=gb:U49837.1 gb:U72899.1 gb:NM_003476.1 gb:AF121260.1 gb:U20324.1 NM_003476 cysteine and glycine-rich protein 3 (cardiac LIM protein) CSRP3 8048 NM_003476 /// XM_006718339 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0003300 // cardiac muscle hypertrophy // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0035995 // detection of muscle stretch // inferred from mutant phenotype /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0031433 // telethonin binding // inferred from direct assay /// 0031433 // telethonin binding // inferred from physical interaction /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 205554_s_at NM_004944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004944.1 /DEF=Homo sapiens deoxyribonuclease I-like 3 (DNASE1L3), mRNA. /FEA=mRNA /GEN=DNASE1L3 /PROD=deoxyribonuclease I-like 3 /DB_XREF=gi:4826697 /UG=Hs.88646 deoxyribonuclease I-like 3 /FL=gb:U56814.1 gb:AF047354.1 gb:NM_004944.1 NM_004944 deoxyribonuclease I-like 3 DNASE1L3 1776 NM_001256560 /// NM_004944 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010623 // developmental programmed cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation 205555_s_at D31771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D31771.1 /DEF=Homo sapiens mRNA for MSX-2, complete cds. /FEA=mRNA /GEN=HDPMSX2A /PROD=MSX-2 /DB_XREF=gi:1321637 /UG=Hs.89404 msh (Drosophila) homeo box homolog 2 /FL=gb:D31771.1 gb:NM_002449.2 D31771 msh homeobox 2 MSX2 4488 NM_002449 /// XM_006714868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003416 // endochondral bone growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0035880 // embryonic nail plate morphogenesis // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // traceable author statement /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0061312 // BMP signaling pathway involved in heart development // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation /// 0090427 // activation of meiosis // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001055 // positive regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 205556_at NM_002449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002449.2 /DEF=Homo sapiens msh (Drosophila) homeo box homolog 2 (MSX2), mRNA. /FEA=mRNA /GEN=MSX2 /PROD=msh homeo box homolog 2 /DB_XREF=gi:6996018 /UG=Hs.89404 msh (Drosophila) homeo box homolog 2 /FL=gb:D31771.1 gb:NM_002449.2 NM_002449 msh homeobox 2 MSX2 4488 NM_002449 /// XM_006714868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003416 // endochondral bone growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0035880 // embryonic nail plate morphogenesis // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // traceable author statement /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0061312 // BMP signaling pathway involved in heart development // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation /// 0090427 // activation of meiosis // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001055 // positive regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 205557_at NM_001725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001725.1 /DEF=Homo sapiens bactericidalpermeability-increasing protein (BPI), mRNA. /FEA=mRNA /GEN=BPI /PROD=bactericidalpermeability-increasing proteinprecursor /DB_XREF=gi:4502446 /UG=Hs.89535 bactericidalpermeability-increasing protein /FL=gb:AF322588.1 gb:J04739.1 gb:NM_001725.1 NM_001725 bactericidal/permeability-increasing protein /// uncharacterized LOC149684 BPI /// LOC149684 671 /// 149684 NM_001725 /// NR_104170 /// XM_005260522 /// XM_005260523 /// XR_244148 /// XR_430313 0006955 // immune response // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043031 // negative regulation of macrophage activation // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 205558_at NM_004620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004620.1 /DEF=Homo sapiens TNF receptor-associated factor 6 (TRAF6), mRNA. /FEA=mRNA /GEN=TRAF6 /PROD=TNF receptor-associated factor 6 /DB_XREF=gi:4759253 /UG=Hs.90957 TNF receptor-associated factor 6 /FL=gb:U78798.1 gb:NM_004620.1 NM_004620 TNF receptor-associated factor 6, E3 ubiquitin protein ligase TRAF6 7189 NM_004620 /// NM_145803 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0001503 // ossification // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0007254 // JNK cascade // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // non-traceable author statement /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0046849 // bone remodeling // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048468 // cell development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from genetic interaction /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 205559_s_at NM_006200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006200.1 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 5 (PCSK5), mRNA. /FEA=mRNA /GEN=PCSK5 /PROD=proprotein convertase subtilisinkexin type 5 /DB_XREF=gi:11321618 /UG=Hs.94376 proprotein convertase subtilisinkexin type 5 /FL=gb:NM_006200.1 gb:U56387.2 NM_006200 proprotein convertase subtilisin/kexin type 5 PCSK5 5125 NM_001190482 /// NM_006200 /// NR_120409 /// XM_005252039 0001822 // kidney development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002001 // renin secretion into blood stream // inferred from expression pattern /// 0006465 // signal peptide processing // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019058 // viral life cycle // inferred from expression pattern /// 0019058 // viral life cycle // inferred from sequence or structural similarity /// 0030323 // respiratory tube development // inferred from sequence or structural similarity /// 0032455 // nerve growth factor processing // traceable author statement /// 0035108 // limb morphogenesis // inferred from sequence or structural similarity /// 0042089 // cytokine biosynthetic process // inferred from sequence or structural similarity /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005796 // Golgi lumen // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity 205560_at NM_006200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006200.1 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 5 (PCSK5), mRNA. /FEA=mRNA /GEN=PCSK5 /PROD=proprotein convertase subtilisinkexin type 5 /DB_XREF=gi:11321618 /UG=Hs.94376 proprotein convertase subtilisinkexin type 5 /FL=gb:NM_006200.1 gb:U56387.2 NM_006200 proprotein convertase subtilisin/kexin type 5 PCSK5 5125 NM_001190482 /// NM_006200 /// NR_120409 /// XM_005252039 0001822 // kidney development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002001 // renin secretion into blood stream // inferred from expression pattern /// 0006465 // signal peptide processing // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019058 // viral life cycle // inferred from expression pattern /// 0019058 // viral life cycle // inferred from sequence or structural similarity /// 0030323 // respiratory tube development // inferred from sequence or structural similarity /// 0032455 // nerve growth factor processing // traceable author statement /// 0035108 // limb morphogenesis // inferred from sequence or structural similarity /// 0042089 // cytokine biosynthetic process // inferred from sequence or structural similarity /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005796 // Golgi lumen // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity 205561_at NM_024681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024681.1 /DEF=Homo sapiens hypothetical protein FLJ12242 (FLJ12242), mRNA. /FEA=mRNA /GEN=FLJ12242 /PROD=hypothetical protein FLJ12242 /DB_XREF=gi:13489098 /UG=Hs.94810 hypothetical protein FLJ12242 /FL=gb:NM_024681.1 NM_024681 potassium channel tetramerization domain containing 17 KCTD17 79734 NM_001282684 /// NM_001282685 /// NM_001282686 /// NM_024681 /// XM_005261741 /// XM_005261742 /// XM_005261743 /// XM_005261744 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 205562_at NM_006414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006414.1 /DEF=Homo sapiens ribonuclease P (38kD) (RPP38), mRNA. /FEA=mRNA /GEN=RPP38 /PROD=ribonuclease P (38kD) /DB_XREF=gi:5454025 /UG=Hs.94986 ribonuclease P (38kD) /FL=gb:U77664.1 gb:NM_006414.1 NM_006414 ribonuclease P/MRP 38kDa subunit RPP38 10557 NM_001097590 /// NM_001265601 /// NM_006414 /// NM_183005 /// XM_006717363 /// XM_006717364 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005634 // nucleus // traceable author statement /// 0005655 // nucleolar ribonuclease P complex // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 205563_at NM_002256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002256.1 /DEF=Homo sapiens KiSS-1 metastasis-suppressor (KISS1), mRNA. /FEA=mRNA /GEN=KISS1 /PROD=kiSS-1 metastasis-suppressor /DB_XREF=gi:4504872 /UG=Hs.95008 KiSS-1 metastasis-suppressor /FL=gb:U43527.1 gb:NM_002256.1 NM_002256 KiSS-1 metastasis-suppressor KISS1 3814 NM_002256 0007010 // cytoskeleton organization // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0033686 // positive regulation of luteinizing hormone secretion // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060112 // generation of ovulation cycle rhythm // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031773 // kisspeptin receptor binding // inferred from electronic annotation 205564_at NM_007003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007003.1 /DEF=Homo sapiens JM27 protein (JM27), mRNA. /FEA=mRNA /GEN=JM27 /PROD=JM27 protein /DB_XREF=gi:5901985 /UG=Hs.95420 JM27 protein /FL=gb:AJ005894.1 gb:NM_007003.1 gb:AF275258.1 NM_007003 P antigen family, member 4 (prostate associated) PAGE4 9506 NM_007003 /// XM_005272740 /// XM_005272741 /// XM_006724571 205565_s_at NM_000144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000144.1 /DEF=Homo sapiens Friedreich ataxia (FRDA), mRNA. /FEA=mRNA /GEN=FRDA /PROD=Friedreich ataxia /DB_XREF=gi:4503784 /UG=Hs.95998 Friedreich ataxia /FL=gb:U43747.1 gb:NM_000144.1 NM_000144 frataxin FXN 2395 NM_000144 /// NM_001161706 /// NM_181425 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006783 // heme biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from mutant phenotype /// 0010722 // regulation of ferrochelatase activity // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from direct assay /// 0018283 // iron incorporation into metallo-sulfur cluster // inferred from direct assay /// 0019230 // proprioception // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0048554 // positive regulation of metalloenzyme activity // inferred from mutant phenotype /// 0051347 // positive regulation of transferase activity // inferred from mutant phenotype /// 0051349 // positive regulation of lyase activity // inferred from direct assay /// 0051349 // positive regulation of lyase activity // inferred from mutant phenotype /// 0051353 // positive regulation of oxidoreductase activity // inferred from mutant phenotype /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay 0004322 // ferroxidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008199 // ferric iron binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0034986 // iron chaperone activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from direct assay /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay 205566_at NM_007011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007011.1 /DEF=Homo sapiens putative transmembrane protein (HS1-2), mRNA. /FEA=mRNA /GEN=HS1-2 /PROD=putative transmembrane protein /DB_XREF=gi:5901977 /UG=Hs.99364 putative transmembrane protein /FL=gb:NM_007011.1 NM_007011 abhydrolase domain containing 2 ABHD2 11057 NM_007011 /// NM_152924 /// XM_005254832 /// XM_005254833 0008152 // metabolic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 205567_at NM_003654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003654.1 /DEF=Homo sapiens carbohydrate (chondroitin 6keratan) sulfotransferase 1 (CHST1), mRNA. /FEA=mRNA /GEN=CHST1 /PROD=carbohydrate (chondroitin 6keratan)sulfotransferase 1 /DB_XREF=gi:4502840 /UG=Hs.104576 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 /FL=gb:U65637.1 gb:AB003791.1 gb:AF090137.1 gb:NM_003654.1 NM_003654 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 CHST1 8534 NM_003654 /// XM_006718356 /// XM_006718357 /// XR_428858 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // inferred from direct assay /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0045130 // keratan sulfotransferase activity // inferred from direct assay 205568_at NM_020980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020980.2 /DEF=Homo sapiens aquaporin 9 (AQP9), mRNA. /FEA=mRNA /GEN=AQP9 /PROD=aquaporin 9 /DB_XREF=gi:11038652 /UG=Hs.104624 aquaporin 9 /FL=gb:NM_020980.2 gb:AB008775.1 gb:AF016495.1 NM_020980 aquaporin 9 AQP9 366 NM_020980 0006810 // transport // traceable author statement /// 0006833 // water transport // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0006863 // purine nucleobase transport // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0006970 // response to osmotic stress // traceable author statement /// 0007588 // excretion // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0015722 // canalicular bile acid transport // inferred from electronic annotation /// 0015791 // polyol transport // inferred from direct assay /// 0015793 // glycerol transport // traceable author statement /// 0015837 // amine transport // inferred from direct assay /// 0015855 // pyrimidine nucleobase transport // inferred from direct assay /// 0030104 // water homeostasis // non-traceable author statement /// 0046689 // response to mercury ion // inferred from direct assay /// 0046942 // carboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0072531 // pyrimidine-containing compound transmembrane transport // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005275 // amine transmembrane transporter activity // traceable author statement /// 0005345 // purine nucleobase transmembrane transporter activity // inferred from direct assay /// 0005350 // pyrimidine nucleobase transmembrane transporter activity // inferred from direct assay /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015166 // polyol transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // inferred from direct assay /// 0015254 // glycerol channel activity // not recorded /// 0015288 // porin activity // non-traceable author statement /// 0046943 // carboxylic acid transmembrane transporter activity // traceable author statement 205569_at NM_014398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014398.1 /DEF=Homo sapiens similar to lysosome-associated membrane glycoprotein (TSC403), mRNA. /FEA=mRNA /GEN=TSC403 /PROD=similar to lysosome-associated membraneglycoprotein /DB_XREF=gi:7657660 /UG=Hs.10887 similar to lysosome-associated membrane glycoprotein /FL=gb:AB013924.1 gb:NM_014398.1 NM_014398 lysosomal-associated membrane protein 3 LAMP3 27074 NM_014398 /// XM_005247360 /// XM_006713586 0002376 // immune system process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097233 // alveolar lamellar body membrane // inferred from electronic annotation 205570_at NM_005028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005028.2 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type II, alpha (PIP5K2A), mRNA. /FEA=mRNA /GEN=PIP5K2A /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeII, alpha /DB_XREF=gi:6857819 /UG=Hs.108966 phosphatidylinositol-4-phosphate 5-kinase, type II, alpha /FL=gb:U14957.2 gb:NM_005028.2 NM_005028 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha PIP4K2A 5305 NM_005028 /// XM_006717450 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // non-traceable author statement /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205571_at NM_015929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015929.1 /DEF=Homo sapiens lipoyltransferase (LOC51601), mRNA. /FEA=mRNA /GEN=LOC51601 /PROD=lipoyltransferase /DB_XREF=gi:7706251 /UG=Hs.112356 lipoyltransferase /FL=gb:AB017566.1 gb:NM_015929.1 NM_015929 lipoyltransferase 1 LIPT1 51601 NM_001204830 /// NM_015929 /// NM_145196 /// NM_145197 /// NM_145198 /// NM_145199 /// NR_037935 /// NR_037936 0006464 // cellular protein modification process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0009249 // protein lipoylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 205572_at NM_001147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001147.1 /DEF=Homo sapiens angiopoietin 2 (ANGPT2), mRNA. /FEA=mRNA /GEN=ANGPT2 /PROD=angiopoietin 2 /DB_XREF=gi:4557314 /UG=Hs.115181 angiopoietin 2 /FL=gb:AF004327.1 gb:NM_001147.1 gb:AB009865.1 NM_001147 angiopoietin 2 ANGPT2 285 NM_001118887 /// NM_001118888 /// NM_001147 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0050928 // negative regulation of positive chemotaxis // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072012 // glomerulus vasculature development // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205573_s_at NM_015976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015976.1 /DEF=Homo sapiens sorting nexin 7 (SNX7), mRNA. /FEA=mRNA /GEN=SNX7 /PROD=sorting nexin 7 /DB_XREF=gi:7706714 /UG=Hs.127241 sorting nexin 7 /FL=gb:AF121857.1 gb:NM_015976.1 NM_015976 sorting nexin 7 SNX7 51375 NM_015976 /// NM_152238 /// NR_033716 /// XM_006710677 /// XM_006710678 /// XM_006710679 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006915 // apoptotic process // not recorded /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005768 // endosome // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded 205574_x_at NM_001199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001199.1 /DEF=Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant BMP1-1, mRNA. /FEA=mRNA /GEN=BMP1 /PROD=bone morphogenetic protein 1, isoform 1,precursor /DB_XREF=gi:4502420 /UG=Hs.1274 bone morphogenetic protein 1 /FL=gb:NM_001199.1 NM_001199 bone morphogenetic protein 1 BMP1 649 NM_001199 /// NM_006128 /// NM_006129 /// NM_006130 /// NM_006131 /// NM_006132 /// NR_033403 /// NR_033404 /// XM_006716386 /// XR_428315 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205575_at NM_006688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006688.1 /DEF=Homo sapiens C1q-related factor (CRF), mRNA. /FEA=mRNA /GEN=CRF /PROD=C1q-related factor /DB_XREF=gi:5729784 /UG=Hs.134012 C1q-related factor /FL=gb:AF095154.1 gb:NM_006688.1 NM_006688 complement component 1, q subcomponent-like 1 C1QL1 10882 NM_006688 0007626 // locomotory behavior // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205576_at NM_000185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000185.2 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 (SERPIND1), mRNA. /FEA=mRNA /GEN=SERPIND1 /PROD=heparin cofactor II precursor /DB_XREF=gi:7262380 /UG=Hs.1478 serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 /FL=gb:M12849.1 gb:NM_000185.2 NM_000185 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 SERPIND1 3053 NM_000185 /// XM_005261597 0006935 // chemotaxis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205577_at NM_005609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005609.1 /DEF=Homo sapiens phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) (PYGM), mRNA. /FEA=mRNA /GEN=PYGM /PROD=glycogen phosphorylase /DB_XREF=gi:5032008 /UG=Hs.154084 phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) /FL=gb:AF066859.1 gb:NM_005609.1 NM_005609 phosphorylase, glycogen, muscle PYGM 5837 NM_001164716 /// NM_005609 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0008184 // glycogen phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 205578_at NM_004560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004560.1 /DEF=Homo sapiens receptor tyrosine kinase-like orphan receptor 2 (ROR2), mRNA. /FEA=mRNA /GEN=ROR2 /PROD=receptor tyrosine kinase-like orphan receptor 2 /DB_XREF=gi:4758841 /UG=Hs.155585 receptor tyrosine kinase-like orphan receptor 2 /FL=gb:M97639.1 gb:NM_004560.1 NM_004560 receptor tyrosine kinase-like orphan receptor 2 ROR2 4920 NM_004560 /// XM_005252008 /// XM_005252009 /// XM_006717121 0001501 // skeletal system development // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from physical interaction 205579_at NM_000861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000861.2 /DEF=Homo sapiens histamine receptor H1 (HRH1), mRNA. /FEA=mRNA /GEN=HRH1 /PROD=histamine receptor H1 /DB_XREF=gi:13435403 /UG=Hs.1570 histamine receptor H1 /FL=gb:NM_000861.2 gb:AF026261.1 gb:D28481.1 NM_000861 histamine receptor H1 HRH1 3269 NM_000861 /// NM_001098211 /// NM_001098212 /// NM_001098213 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0043114 // regulation of vascular permeability // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048245 // eosinophil chemotaxis // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004969 // histamine receptor activity // inferred from sequence or structural similarity 205580_s_at D28481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28481.1 /DEF=Human mRNA for histamine H1 receptor, complete cds. /FEA=mRNA /PROD=histamine H1 receptor /DB_XREF=gi:457654 /UG=Hs.1570 histamine receptor H1 /FL=gb:NM_000861.2 gb:AF026261.1 gb:D28481.1 D28481 histamine receptor H1 HRH1 3269 NM_000861 /// NM_001098211 /// NM_001098212 /// NM_001098213 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0043114 // regulation of vascular permeability // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048245 // eosinophil chemotaxis // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004969 // histamine receptor activity // inferred from sequence or structural similarity 205581_s_at NM_000603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000603.1 /DEF=Homo sapiens nitric oxide synthase 3 (endothelial cell) (NOS3), mRNA. /FEA=mRNA /GEN=NOS3 /PROD=nitric oxide synthase 3 (endothelial cell) /DB_XREF=gi:10835160 /UG=Hs.166373 nitric oxide synthase 3 (endothelial cell) /FL=gb:NM_000603.1 gb:M93718.1 gb:M95296.1 NM_000603 nitric oxide synthase 3 (endothelial cell) NOS3 4846 NM_000603 /// NM_001160109 /// NM_001160110 /// NM_001160111 /// XM_006716000 /// XM_006716001 /// XM_006716002 0001525 // angiogenesis // inferred from electronic annotation /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0003057 // regulation of the force of heart contraction by chemical signal // inferred from electronic annotation /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from mutant phenotype /// 0006527 // arginine catabolic process // inferred from direct assay /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007263 // nitric oxide mediated signal transduction // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0009408 // response to heat // non-traceable author statement /// 0010544 // negative regulation of platelet activation // non-traceable author statement /// 0014740 // negative regulation of muscle hyperplasia // inferred from sequence or structural similarity /// 0014806 // smooth muscle hyperplasia // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from mutant phenotype /// 0031284 // positive regulation of guanylate cyclase activity // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from expression pattern /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // not recorded /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050880 // regulation of blood vessel size // inferred from sequence or structural similarity /// 0050880 // regulation of blood vessel size // non-traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0003785 // actin monomer binding // inferred from physical interaction /// 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0004517 // nitric-oxide synthase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0010181 // FMN binding // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0034617 // tetrahydrobiopterin binding // inferred from direct assay /// 0034618 // arginine binding // inferred from direct assay /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // non-traceable author statement /// 0050661 // NADP binding // non-traceable author statement 205582_s_at NM_004121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004121.1 /DEF=Homo sapiens gamma-glutamyltransferase-like activity 1 (GGTLA1), mRNA. /FEA=mRNA /GEN=GGTLA1 /PROD=gamma-glutamyltransferase-like activity 1 /DB_XREF=gi:4758431 /UG=Hs.1675 gamma-glutamyltransferase-like activity 1 /FL=gb:M64099.1 gb:NM_004121.1 NM_004121 gamma-glutamyltransferase 5 GGT5 2687 NM_001099781 /// NM_001099782 /// NM_004121 /// XM_005261557 /// XM_005261558 /// XM_005261559 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from electronic annotation 205583_s_at NM_024810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024810.1 /DEF=Homo sapiens hypothetical protein FLJ23018 (FLJ23018), mRNA. /FEA=mRNA /GEN=FLJ23018 /PROD=hypothetical protein FLJ23018 /DB_XREF=gi:13376194 /UG=Hs.169078 hypothetical protein FLJ23018 /FL=gb:NM_024810.1 NM_024810 ALG13, UDP-N-acetylglucosaminyltransferase subunit ALG13 79868 NM_001039210 /// NM_001099922 /// NM_001168385 /// NM_001257230 /// NM_001257231 /// NM_001257234 /// NM_001257235 /// NM_001257237 /// NM_001257239 /// NM_001257240 /// NM_001257241 /// NM_018466 /// NR_033125 /// XM_005262191 /// XM_006724693 /// XM_006724694 /// XM_006724695 /// XM_006724696 /// XM_006724697 /// XM_006724698 /// XM_006724699 /// XM_006724700 /// XM_006724701 /// XM_006724702 /// XM_006724703 /// XM_006724704 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004577 // N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205584_at NM_024810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024810.1 /DEF=Homo sapiens hypothetical protein FLJ23018 (FLJ23018), mRNA. /FEA=mRNA /GEN=FLJ23018 /PROD=hypothetical protein FLJ23018 /DB_XREF=gi:13376194 /UG=Hs.169078 hypothetical protein FLJ23018 /FL=gb:NM_024810.1 NM_024810 ALG13, UDP-N-acetylglucosaminyltransferase subunit ALG13 79868 NM_001039210 /// NM_001099922 /// NM_001168385 /// NM_001257230 /// NM_001257231 /// NM_001257234 /// NM_001257235 /// NM_001257237 /// NM_001257239 /// NM_001257240 /// NM_001257241 /// NM_018466 /// NR_033125 /// XM_005262191 /// XM_006724693 /// XM_006724694 /// XM_006724695 /// XM_006724696 /// XM_006724697 /// XM_006724698 /// XM_006724699 /// XM_006724700 /// XM_006724701 /// XM_006724702 /// XM_006724703 /// XM_006724704 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004577 // N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205585_at NM_001987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001987.1 /DEF=Homo sapiens ets variant gene 6 (TEL oncogene) (ETV6), mRNA. /FEA=mRNA /GEN=ETV6 /PROD=ets variant gene 6 (TEL oncogene) /DB_XREF=gi:4503610 /UG=Hs.169081 ets variant gene 6 (TEL oncogene) /FL=gb:NM_001987.1 gb:U11732.1 NM_001987 ets variant 6 ETV6 2120 NM_001987 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006959 // humoral immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205586_x_at NM_003378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003378.1 /DEF=Homo sapiens VGF nerve growth factor inducible (VGF), mRNA. /FEA=mRNA /GEN=VGF /PROD=VGF nerve growth factor inducible /DB_XREF=gi:4507888 /UG=Hs.171014 VGF nerve growth factor inducible /FL=gb:NM_003378.1 NM_003378 VGF nerve growth factor inducible VGF 7425 NM_003378 /// XM_005250560 /// XM_005250561 0001541 // ovarian follicle development // inferred from electronic annotation /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from expression pattern 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 205587_at NM_007045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007045.1 /DEF=Homo sapiens FGFR1 oncogene partner (FOP), mRNA. /FEA=mRNA /GEN=FOP /PROD=FGFR1 oncogene partner /DB_XREF=gi:5901953 /UG=Hs.180296 FGFR1 oncogene partner /FL=gb:NM_007045.1 NM_007045 FGFR1 oncogene partner FGFR1OP 11116 NM_001278690 /// NM_007045 /// NM_194429 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay 205588_s_at NM_007045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007045.1 /DEF=Homo sapiens FGFR1 oncogene partner (FOP), mRNA. /FEA=mRNA /GEN=FOP /PROD=FGFR1 oncogene partner /DB_XREF=gi:5901953 /UG=Hs.180296 FGFR1 oncogene partner /FL=gb:NM_007045.1 NM_007045 FGFR1 oncogene partner FGFR1OP 11116 NM_001278690 /// NM_007045 /// NM_194429 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay 205589_at NM_000258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000258.1 /DEF=Homo sapiens myosin, light polypeptide 3, alkali; ventricular, skeletal, slow (MYL3), mRNA. /FEA=mRNA /GEN=MYL3 /PROD=myosin light chain 3 /DB_XREF=gi:4557776 /UG=Hs.1815 myosin, light polypeptide 3, alkali; ventricular, skeletal, slow /FL=gb:M24122.1 gb:NM_000258.1 gb:AF174483.1 NM_000258 myosin, light chain 3, alkali; ventricular, skeletal, slow MYL3 4634 NM_000258 0002026 // regulation of the force of heart contraction // inferred from mutant phenotype /// 0006942 // regulation of striated muscle contraction // inferred from mutant phenotype /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0031672 // A band // inferred from direct assay /// 0031674 // I band // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement /// 0032038 // myosin II heavy chain binding // non-traceable author statement 205590_at NM_005739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005739.2 /DEF=Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), mRNA. /FEA=mRNA /GEN=RASGRP1 /PROD=RAS guanyl releasing protein 1 /DB_XREF=gi:6382080 /UG=Hs.182591 RAS guanyl releasing protein 1 (calcium and DAG-regulated) /FL=gb:AF081195.1 gb:AF106071.1 gb:NM_005739.2 NM_005739 RAS guanyl releasing protein 1 (calcium and DAG-regulated) RASGRP1 10125 NM_001128602 /// NM_005739 /// XM_005254114 0001816 // cytokine production // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0014066 // regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032856 // activation of Ras GTPase activity // inferred from electronic annotation /// 0032862 // activation of Rho GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043303 // mast cell degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0042629 // mast cell granule // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008289 // lipid binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205591_at NM_006334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006334.1 /DEF=Homo sapiens neuroblastoma (nerve tissue) protein (AMY), mRNA. /FEA=mRNA /GEN=AMY /PROD=neuroblastoma (nerve tissue) protein /DB_XREF=gi:5453546 /UG=Hs.18551 neuroblastoma (nerve tissue) protein /FL=gb:D82343.1 gb:NM_006334.1 NM_006334 olfactomedin 1 OLFM1 10439 NM_001282611 /// NM_001282612 /// NM_006334 /// NM_014279 /// NM_058199 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205592_at X77737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X77737.1 /DEF=H.sapiens mRNA for red cell anion exchanger (EPB3, AE1, Band 3) 3 non-coding region. /FEA=mRNA /PROD=anion exchanger /DB_XREF=gi:535096 /UG=Hs.185923 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) /FL=gb:M27819.1 gb:NM_000342.1 X77737 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) SLC4A1 6521 NM_000342 /// XM_005257592 /// XM_005257593 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from sequence or structural similarity /// 0006873 // cellular ion homeostasis // traceable author statement /// 0015701 // bicarbonate transport // inferred from direct assay /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from direct assay /// 0005452 // inorganic anion exchanger activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // traceable author statement /// 0015106 // bicarbonate transmembrane transporter activity // inferred from direct assay /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015301 // anion:anion antiporter activity // inferred from direct assay /// 0030506 // ankyrin binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043495 // protein anchor // traceable author statement 205593_s_at NM_002606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002606.1 /DEF=Homo sapiens phosphodiesterase 9A (PDE9A), mRNA. /FEA=mRNA /GEN=PDE9A /PROD=phosphodiesterase 9A /DB_XREF=gi:4505674 /UG=Hs.18953 phosphodiesterase 9A /FL=gb:AF048837.1 gb:AF067223.1 gb:NM_002606.1 NM_002606 phosphodiesterase 9A PDE9A 5152 NM_001001567 /// NM_001001568 /// NM_001001569 /// NM_001001570 /// NM_001001571 /// NM_001001572 /// NM_001001573 /// NM_001001574 /// NM_001001575 /// NM_001001576 /// NM_001001577 /// NM_001001578 /// NM_001001579 /// NM_001001580 /// NM_001001581 /// NM_001001582 /// NM_001001583 /// NM_001001584 /// NM_001001585 /// NM_002606 /// XM_005261132 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 205594_at NM_014897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014897.1 /DEF=Homo sapiens KIAA0924 protein (KIAA0924), mRNA. /FEA=mRNA /GEN=KIAA0924 /PROD=KIAA0924 protein /DB_XREF=gi:7662383 /UG=Hs.190386 KIAA0924 protein /FL=gb:AB023141.1 gb:NM_014897.1 NM_014897 zinc finger protein 652 ZNF652 22834 NM_001145365 /// NM_014897 /// XM_005257166 /// XM_006721774 /// XM_006721775 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205595_at NM_001944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001944.1 /DEF=Homo sapiens desmoglein 3 (pemphigus vulgaris antigen) (DSG3), mRNA. /FEA=mRNA /GEN=DSG3 /PROD=desmoglein 3 preproprotein /DB_XREF=gi:4503404 /UG=Hs.1925 desmoglein 3 (pemphigus vulgaris antigen) /FL=gb:M76482.1 gb:NM_001944.1 NM_001944 desmoglein 3 DSG3 1830 NM_001944 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205596_s_at AY014180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY014180.1 /DEF=Homo sapiens E3 ubiquitin ligase Smurf2 mRNA, complete cds. /FEA=mRNA /PROD=E3 ubiquitin ligase Smurf2 /DB_XREF=gi:12408118 /UG=Hs.194477 E3 ubiquitin ligase SMURF2 /FL=gb:AF301463.1 gb:AF310676.1 gb:NM_022739.1 gb:AY014180.1 AY014180 SMAD specific E3 ubiquitin protein ligase 2 SMURF2 64750 NM_022739 /// XM_005257585 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // not recorded /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // not recorded /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction 205597_at NM_025257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025257.1 /DEF=Homo sapiens NG22 protein (NG22), mRNA. /FEA=mRNA /GEN=NG22 /PROD=NG22 protein /DB_XREF=gi:13376867 /UG=Hs.199839 NG22 protein /FL=gb:NM_025257.1 NM_025257 solute carrier family 44, member 4 SLC44A4 80736 NM_001178044 /// NM_001178045 /// NM_025257 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0008292 // acetylcholine biosynthetic process // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0061526 // acetylcholine secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 205598_at NM_005879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005879.1 /DEF=Homo sapiens TRAF interacting protein (TRIP), mRNA. /FEA=mRNA /GEN=TRIP /PROD=TRAF interacting protein /DB_XREF=gi:5032194 /UG=Hs.21254 TRAF interacting protein /FL=gb:BC000310.1 gb:U77845.1 gb:NM_005879.1 NM_005879 TRAF interacting protein TRAIP 10293 NM_005879 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205599_at NM_005658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005658.1 /DEF=Homo sapiens TNF receptor-associated factor 1 (TRAF1), mRNA. /FEA=mRNA /GEN=TRAF1 /PROD=TNF receptor-associated factor 1 /DB_XREF=gi:5032192 /UG=Hs.2134 TNF receptor-associated factor 1 /FL=gb:NM_005658.1 gb:U19261.1 NM_005658 TNF receptor-associated factor 1 TRAF1 7185 NM_001190945 /// NM_001190947 /// NM_005658 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // traceable author statement 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction 205600_x_at AI052747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI052747 /FEA=EST /DB_XREF=gi:3308738 /DB_XREF=est:oz27d05.x1 /CLONE=IMAGE:1676553 /UG=Hs.22554 homeo box B5 /FL=gb:M92299.1 gb:NM_002147.1 AI052747 homeobox B5 HOXB5 3215 NM_002147 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205601_s_at NM_002147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002147.1 /DEF=Homo sapiens homeo box B5 (HOXB5), mRNA. /FEA=mRNA /GEN=HOXB5 /PROD=homeo box B5 /DB_XREF=gi:4504468 /UG=Hs.22554 homeo box B5 /FL=gb:M92299.1 gb:NM_002147.1 NM_002147 homeobox B5 HOXB5 3215 NM_002147 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205602_x_at NM_002783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002783.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 7 (PSG7), mRNA. /FEA=mRNA /GEN=PSG7 /PROD=pregnancy specific beta-1-glycoprotein 7 /DB_XREF=gi:4506176 /UG=Hs.225932 pregnancy specific beta-1-glycoprotein 7 /FL=gb:NM_002783.1 gb:U18467.1 NM_002783 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) PSG7 5676 NM_001206650 /// NM_001290042 /// NM_002783 /// NR_073194 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 205603_s_at NM_007309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007309.1 /DEF=Homo sapiens diaphanous (Drosophila, homolog) 2 (DIAPH2), transcript variant 12C, mRNA. /FEA=mRNA /GEN=DIAPH2 /PROD=diaphanous 2 isoform 12C /DB_XREF=gi:6382070 /UG=Hs.226483 diaphanous (Drosophila, homolog) 2 /FL=gb:NM_007309.1 NM_007309 diaphanous-related formin 2 DIAPH2 1730 NM_006729 /// NM_007309 0000910 // cytokinesis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 205604_at AI432470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI432470 /FEA=EST /DB_XREF=gi:4281954 /DB_XREF=est:tg73h09.x1 /CLONE=IMAGE:2114465 /UG=Hs.236646 homeo box D9 /FL=gb:NM_014213.1 AI432470 homeobox D9 HOXD9 3235 NM_014213 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205605_at NM_014213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014213.1 /DEF=Homo sapiens homeo box D9 (HOXD9), mRNA. /FEA=mRNA /GEN=HOXD9 /PROD=homeo box D9 /DB_XREF=gi:7657169 /UG=Hs.236646 homeo box D9 /FL=gb:NM_014213.1 NM_014213 homeobox D9 HOXD9 3235 NM_014213 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205606_at NM_002336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002336.1 /DEF=Homo sapiens low density lipoprotein receptor-related protein 6 (LRP6), mRNA. /FEA=mRNA /GEN=LRP6 /PROD=low density lipoprotein receptor-related protein6 /DB_XREF=gi:4505016 /UG=Hs.23672 low density lipoprotein receptor-related protein 6 /FL=gb:AF074264.1 gb:NM_002336.1 NM_002336 low density lipoprotein receptor-related protein 6 LRP6 4040 NM_002336 /// XM_006719078 /// XR_429034 /// XR_429035 0001702 // gastrulation with mouth forming second // not recorded /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // not recorded /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003344 // pericardium morphogenesis // not recorded /// 0003401 // axis elongation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // not recorded /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // not recorded /// 0014029 // neural crest formation // inferred from direct assay /// 0014033 // neural crest cell differentiation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // not recorded /// 0021794 // thalamus development // not recorded /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from electronic annotation /// 0021872 // forebrain generation of neurons // inferred from electronic annotation /// 0021874 // Wnt signaling pathway involved in forebrain neuroblast division // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0021987 // cerebral cortex development // not recorded /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030278 // regulation of ossification // not recorded /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // not recorded /// 0030917 // midbrain-hindbrain boundary development // not recorded /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from mutant phenotype /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035261 // external genitalia morphogenesis // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // not recorded /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 0044335 // canonical Wnt signaling pathway involved in neural crest cell differentiation // inferred by curator /// 0044340 // canonical Wnt signaling pathway involved in regulation of cell proliferation // inferred by curator /// 0045598 // regulation of fat cell differentiation // not recorded /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046849 // bone remodeling // not recorded /// 0048596 // embryonic camera-type eye morphogenesis // not recorded /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060021 // palate development // not recorded /// 0060026 // convergent extension // not recorded /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060284 // regulation of cell development // inferred from electronic annotation /// 0060325 // face morphogenesis // not recorded /// 0060349 // bone morphogenesis // not recorded /// 0060444 // branching involved in mammary gland duct morphogenesis // not recorded /// 0060535 // trachea cartilage morphogenesis // not recorded /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0061310 // canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development // inferred from electronic annotation /// 0061324 // canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090009 // primitive streak formation // not recorded /// 0090118 // receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport // not recorded /// 0090244 // Wnt signaling pathway involved in somitogenesis // not recorded /// 0090245 // axis elongation involved in somitogenesis // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1901998 // toxin transport // inferred from mutant phenotype /// 2000051 // negative regulation of non-canonical Wnt signaling pathway // inferred from electronic annotation /// 2000055 // positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000149 // negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis // inferred from electronic annotation /// 2000151 // negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 2000162 // negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis // inferred from electronic annotation /// 2000164 // negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis // inferred from electronic annotation /// 2000166 // negative regulation of planar cell polarity pathway involved in pericardium morphogenesis // inferred from electronic annotation /// 2000168 // negative regulation of planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043025 // neuronal cell body // not recorded /// 0043235 // receptor complex // not recorded /// 0045202 // synapse // not recorded 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from mutant phenotype /// 0019534 // toxin transporter activity // inferred from mutant phenotype /// 0034185 // apolipoprotein binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0071936 // coreceptor activity involved in Wnt signaling pathway // inferred from direct assay 205607_s_at NM_020423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020423.1 /DEF=Homo sapiens hypothetical protein LOC57147 (LOC57147), mRNA. /FEA=mRNA /GEN=LOC57147 /PROD=hypothetical protein LOC57147 /DB_XREF=gi:9967093 /UG=Hs.24243 hypothetical protein LOC57147 /FL=gb:NM_020423.1 NM_020423 SCY1-like 3 (S. cerevisiae) SCYL3 57147 NM_020423 /// NM_181093 /// XM_006711465 /// XM_006711466 /// XM_006711467 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205608_s_at U83508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U83508.1 /DEF=Human angiopoietin-1 mRNA, complete cds. /FEA=mRNA /PROD=angiopoietin-1 /DB_XREF=gi:1907326 /UG=Hs.2463 angiopoietin 1 /FL=gb:U83508.1 gb:D13628.1 gb:NM_001146.1 U83508 angiopoietin 1 ANGPT1 284 NM_001146 /// NM_001199859 /// NM_139290 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001936 // regulation of endothelial cell proliferation // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from direct assay /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014842 // regulation of satellite cell proliferation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030210 // heparin biosynthetic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072012 // glomerulus vasculature development // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 205609_at NM_001146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001146.1 /DEF=Homo sapiens angiopoietin 1 (ANGPT1), mRNA. /FEA=mRNA /GEN=ANGPT1 /PROD=angiopoietin 1 /DB_XREF=gi:4502086 /UG=Hs.2463 angiopoietin 1 /FL=gb:U83508.1 gb:D13628.1 gb:NM_001146.1 NM_001146 angiopoietin 1 ANGPT1 284 NM_001146 /// NM_001199859 /// NM_139290 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001936 // regulation of endothelial cell proliferation // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from direct assay /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014842 // regulation of satellite cell proliferation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030210 // heparin biosynthetic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072012 // glomerulus vasculature development // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 205610_at NM_003803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003803.1 /DEF=Homo sapiens myomesin 1 (skelemin) (185kD) (MYOM1), mRNA. /FEA=mRNA /GEN=MYOM1 /PROD=myomesin 1 /DB_XREF=gi:4505312 /UG=Hs.2504 myomesin 1 (skelemin) (185kD) /FL=gb:NM_003803.1 NM_003803 myomesin 1 MYOM1 8736 NM_003803 /// NM_019856 0006936 // muscle contraction // inferred from electronic annotation /// 0006941 // striated muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005863 // striated muscle myosin thick filament // traceable author statement /// 0030016 // myofibril // traceable author statement /// 0030017 // sarcomere // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity /// 0032982 // myosin filament // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 205611_at NM_003809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003809.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12), mRNA. /FEA=mRNA /GEN=TNFSF12 /PROD=tumor necrosis factor (ligand) superfamily,member 12 /DB_XREF=gi:4507596 /UG=Hs.26401 tumor necrosis factor (ligand) superfamily, member 12 /FL=gb:AF030099.1 gb:AF055872.1 gb:NM_003809.1 NM_003809 tumor necrosis factor (ligand) superfamily, member 12 /// TNFSF12-TNFSF13 readthrough TNFSF12 /// TNFSF12-TNFSF13 8742 /// 407977 NM_003809 /// NM_172089 /// NR_037146 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005125 // cytokine activity // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205612_at NM_007351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007351.1 /DEF=Homo sapiens multimerin (MMRN), mRNA. /FEA=mRNA /GEN=MMRN /PROD=multimerin /DB_XREF=gi:6681258 /UG=Hs.268107 multimerin /FL=gb:NM_007351.1 gb:U27109.1 NM_007351 multimerin 1 MMRN1 22915 NM_007351 /// XM_005262856 0002576 // platelet degranulation // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205613_at NM_016524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016524.1 /DEF=Homo sapiens BK protein (LOC51760), mRNA. /FEA=mRNA /GEN=LOC51760 /PROD=BK protein /DB_XREF=gi:7706558 /UG=Hs.26971 BK protein /FL=gb:BC004518.1 gb:AF220560.1 gb:NM_016524.1 NM_016524 synaptotagmin XVII SYT17 51760 NM_016524 /// XM_005255361 /// XM_005255362 /// XM_006721053 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205614_x_at NM_020998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020998.1 /DEF=Homo sapiens macrophage stimulating 1 (hepatocyte growth factor-like) (MST1), mRNA. /FEA=mRNA /GEN=MST1 /PROD=macrophage stimulating 1 (hepatocyte growthfactor-like) /DB_XREF=gi:10337614 /UG=Hs.278657 macrophage stimulating 1 (hepatocyte growth factor-like) /FL=gb:NM_020998.1 gb:M74178.1 gb:L11924.1 NM_020998 macrophage stimulating 1 (hepatocyte growth factor-like) MST1 4485 NM_020998 /// XM_006713166 /// XM_006713167 /// XM_006713168 /// XM_006713169 /// XR_427269 /// XR_427270 /// XR_427271 /// XR_427272 /// XR_427273 /// XR_427274 /// XR_427275 /// XR_427276 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205615_at NM_001868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001868.1 /DEF=Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA. /FEA=mRNA /GEN=CPA1 /PROD=pancreatic carboxypeptidase A1 precursor /DB_XREF=gi:4502996 /UG=Hs.2879 carboxypeptidase A1 (pancreatic) /FL=gb:BC005279.1 gb:NM_001868.1 NM_001868 carboxypeptidase A1 (pancreatic) CPA1 1357 NM_001868 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008238 // exopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205616_at AW134812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134812 /FEA=EST /DB_XREF=gi:6138358 /DB_XREF=est:UI-H-BI1-abs-b-12-0-UI.s1 /CLONE=IMAGE:2712910 /UG=Hs.301306 potassium voltage-gated channel, shaker-related subfamily, member 6 /FL=gb:NM_002235.1 AW134812 polypeptide N-acetylgalactosaminyltransferase 8 /// potassium voltage-gated channel, shaker-related subfamily, member 6 GALNT8 /// KCNA6 3742 /// 26290 NM_002235 /// NM_017417 /// XM_005253686 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205617_at NM_000951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000951.1 /DEF=Homo sapiens proline-rich Gla (G-carboxyglutamic acid) polypeptide 2 (PRRG2), mRNA. /FEA=mRNA /GEN=PRRG2 /PROD=proline-rich Gla (G-carboxyglutamic acid)polypeptide 2 /DB_XREF=gi:4506136 /UG=Hs.35101 proline-rich Gla (G-carboxyglutamic acid) polypeptide 2 /FL=gb:AF009243.1 gb:NM_000951.1 NM_000951 proline rich Gla (G-carboxyglutamic acid) 2 PRRG2 5639 NM_000951 /// XM_005259060 /// XM_006723286 /// XR_430204 0005576 // extracellular region // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205618_at NM_000950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000950.1 /DEF=Homo sapiens proline-rich Gla (G-carboxyglutamic acid) polypeptide 1 (PRRG1), mRNA. /FEA=mRNA /GEN=PRRG1 /PROD=proline-rich Gla (G-carboxyglutamic acid)polypeptide 1 /DB_XREF=gi:4506134 /UG=Hs.40637 proline-rich Gla (G-carboxyglutamic acid) polypeptide 1 /FL=gb:AF009242.1 gb:NM_000950.1 NM_000950 proline rich Gla (G-carboxyglutamic acid) 1 PRRG1 5638 NM_000950 /// NM_001142395 /// NM_001173486 /// NM_001173489 /// NM_001173490 0005576 // extracellular region // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 205619_s_at NM_004527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004527.1 /DEF=Homo sapiens mesenchyme homeo box 1 (MEOX1), transcript variant 1, mRNA. /FEA=mRNA /GEN=MEOX1 /PROD=mesenchyme homeo box 1 isoform 1 /DB_XREF=gi:4758709 /UG=Hs.438 mesenchyme homeo box 1 /FL=gb:NM_004527.1 gb:U10492.1 NM_004527 mesenchyme homeobox 1 MEOX1 4222 NM_001040002 /// NM_004527 /// NM_013999 0001757 // somite specification // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 205620_at NM_000504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000504.2 /DEF=Homo sapiens coagulation factor X (F10), mRNA. /FEA=mRNA /GEN=F10 /PROD=coagulation factor X precursor /DB_XREF=gi:9961350 /UG=Hs.47913 coagulation factor X /FL=gb:M22613.1 gb:M57285.1 gb:NM_000504.2 NM_000504 coagulation factor X F10 2159 NM_000504 /// XM_005268298 /// XM_006719964 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // inferred by curator /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030335 // positive regulation of cell migration // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031233 // intrinsic component of external side of plasma membrane // inferred by curator /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205621_at NM_006020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006020.1 /DEF=Homo sapiens alkylation repair; alkB homolog (ABH), mRNA. /FEA=mRNA /GEN=ABH /PROD=alkylation repair; alkB homolog /DB_XREF=gi:5174384 /UG=Hs.54418 alkylation repair; alkB homolog /FL=gb:NM_006020.1 NM_006020 alkB, alkylation repair homolog 1 (E. coli) ALKBH1 8846 NM_001039506 /// NM_006020 /// XM_005268165 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006307 // DNA dealkylation involved in DNA repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0042245 // RNA repair // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070989 // oxidative demethylation // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0070579 // methylcytosine dioxygenase activity // inferred from direct assay 205622_at NM_003080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003080.1 /DEF=Homo sapiens sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (SMPD2), mRNA. /FEA=mRNA /GEN=SMPD2 /PROD=sphingomyelin phosphodiesterase 2, neutralmembrane (neutral sphingomyelinase) /DB_XREF=gi:4507094 /UG=Hs.55235 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) /FL=gb:BC000038.1 gb:NM_003080.1 NM_003080 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) SMPD2 6610 NM_003080 /// XM_005267109 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006684 // sphingomyelin metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205623_at NM_000691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000691.1 /DEF=Homo sapiens aldehyde dehydrogenase 3 (ALDH3), mRNA. /FEA=mRNA /GEN=ALDH3 /PROD=aldehyde dehydrogenase 3 /DB_XREF=gi:4502034 /UG=Hs.575 aldehyde dehydrogenase 3 family, member A1 /FL=gb:BC004370.1 gb:M77477.1 gb:M74542.1 gb:NM_000691.1 NM_000691 aldehyde dehydrogenase 3 family, member A1 ALDH3A1 218 NM_000691 /// NM_001135167 /// NM_001135168 /// XM_005256522 /// XM_005256523 /// XM_005256524 /// XM_005256525 /// XM_006721473 0001666 // response to hypoxia // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0008106 // alcohol dehydrogenase (NADP+) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 205624_at NM_001870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001870.1 /DEF=Homo sapiens carboxypeptidase A3 (mast cell) (CPA3), mRNA. /FEA=mRNA /GEN=CPA3 /PROD=mast cell carboxypeptidase A3 precursor /DB_XREF=gi:4503000 /UG=Hs.646 carboxypeptidase A3 (mast cell) /FL=gb:M27717.1 gb:NM_001870.1 NM_001870 carboxypeptidase A3 (mast cell) CPA3 1359 NM_001870 /// XM_006713503 0002002 // regulation of angiotensin levels in blood // inferred from electronic annotation /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030141 // secretory granule // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // non-traceable author statement /// 0004181 // metallocarboxypeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205625_s_at AW014927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW014927 /FEA=EST /DB_XREF=gi:5863684 /DB_XREF=est:UI-H-BI0-aaf-f-06-0-UI.s1 /CLONE=IMAGE:2709251 /UG=Hs.65425 calbindin 1, (28kD) /FL=gb:NM_004929.2 AW014927 calbindin 1, 28kDa CALB1 793 NM_004929 0007611 // learning or memory // inferred from electronic annotation /// 0007614 // short-term memory // inferred from mutant phenotype /// 0007616 // long-term memory // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0035502 // metanephric part of ureteric bud development // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0072205 // metanephric collecting duct development // inferred from electronic annotation /// 0072221 // metanephric distal convoluted tubule development // inferred from electronic annotation /// 0072286 // metanephric connecting tubule development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005499 // vitamin D binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 205626_s_at NM_004929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004929.2 /DEF=Homo sapiens calbindin 1, (28kD) (CALB1), mRNA. /FEA=mRNA /GEN=CALB1 /PROD=calbindin 1 /DB_XREF=gi:5579451 /UG=Hs.65425 calbindin 1, (28kD) /FL=gb:NM_004929.2 NM_004929 calbindin 1, 28kDa CALB1 793 NM_004929 0007611 // learning or memory // inferred from electronic annotation /// 0007614 // short-term memory // inferred from mutant phenotype /// 0007616 // long-term memory // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0035502 // metanephric part of ureteric bud development // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0072205 // metanephric collecting duct development // inferred from electronic annotation /// 0072221 // metanephric distal convoluted tubule development // inferred from electronic annotation /// 0072286 // metanephric connecting tubule development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005499 // vitamin D binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 205627_at NM_001785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001785.1 /DEF=Homo sapiens cytidine deaminase (CDA), mRNA. /FEA=mRNA /GEN=CDA /PROD=cytidine deaminase /DB_XREF=gi:11386156 /UG=Hs.72924 cytidine deaminase /FL=gb:NM_001785.1 gb:L27943.1 NM_001785 cytidine deaminase CDA 978 NM_001785 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008655 // pyrimidine-containing compound salvage // non-traceable author statement /// 0009972 // cytidine deamination // inferred from direct assay /// 0019858 // cytosine metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045980 // negative regulation of nucleotide metabolic process // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0001882 // nucleoside binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // not recorded /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205628_at NM_000947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000947.1 /DEF=Homo sapiens primase, polypeptide 2A (58kD) (PRIM2A), mRNA. /FEA=mRNA /GEN=PRIM2A /PROD=primase, polypeptide 2A (58kD) /DB_XREF=gi:4506052 /UG=Hs.74519 primase, polypeptide 2A (58kD) /FL=gb:NM_000947.1 NM_000947 primase, DNA, polypeptide 2 (58kDa) PRIM2 5558 NM_000947 /// NM_001282487 /// NM_001282488 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006269 // DNA replication, synthesis of RNA primer // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 1990077 // primosome complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003896 // DNA primase activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 205629_s_at BC002599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002599.1 /DEF=Homo sapiens, corticotropin releasing hormone, clone MGC:1770, mRNA, complete cds. /FEA=mRNA /PROD=corticotropin releasing hormone /DB_XREF=gi:12803538 /UG=Hs.75294 corticotropin releasing hormone /FL=gb:BC002599.1 gb:NM_000756.1 BC002599 corticotropin releasing hormone CRH 1392 NM_000756 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from direct assay /// 0006704 // glucocorticoid biosynthetic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0010841 // positive regulation of circadian sleep/wake cycle, wakefulness // non-traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014062 // regulation of serotonin secretion // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0033494 // ferulate metabolic process // inferred from electronic annotation /// 0033685 // negative regulation of luteinizing hormone secretion // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042322 // negative regulation of circadian sleep/wake cycle, REM sleep // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045472 // response to ether // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050801 // ion homeostasis // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051461 // positive regulation of corticotropin secretion // inferred from electronic annotation /// 0051464 // positive regulation of cortisol secretion // inferred from direct assay /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060456 // positive regulation of digestive system process // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070093 // negative regulation of glucagon secretion // inferred from electronic annotation /// 0071314 // cellular response to cocaine // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 2000854 // positive regulation of corticosterone secretion // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043196 // varicosity // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017045 // corticotropin-releasing hormone activity // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation /// 0051431 // corticotropin-releasing hormone receptor 2 binding // inferred from electronic annotation 205630_at NM_000756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000756.1 /DEF=Homo sapiens corticotropin releasing hormone (CRH), mRNA. /FEA=mRNA /GEN=CRH /PROD=corticotropin releasing hormone precursor /DB_XREF=gi:4503040 /UG=Hs.75294 corticotropin releasing hormone /FL=gb:BC002599.1 gb:NM_000756.1 NM_000756 corticotropin releasing hormone CRH 1392 NM_000756 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from direct assay /// 0006704 // glucocorticoid biosynthetic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0010841 // positive regulation of circadian sleep/wake cycle, wakefulness // non-traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014062 // regulation of serotonin secretion // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0033494 // ferulate metabolic process // inferred from electronic annotation /// 0033685 // negative regulation of luteinizing hormone secretion // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042322 // negative regulation of circadian sleep/wake cycle, REM sleep // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045472 // response to ether // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050801 // ion homeostasis // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051461 // positive regulation of corticotropin secretion // inferred from electronic annotation /// 0051464 // positive regulation of cortisol secretion // inferred from direct assay /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060456 // positive regulation of digestive system process // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070093 // negative regulation of glucagon secretion // inferred from electronic annotation /// 0071314 // cellular response to cocaine // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 2000854 // positive regulation of corticosterone secretion // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043196 // varicosity // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017045 // corticotropin-releasing hormone activity // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation /// 0051431 // corticotropin-releasing hormone receptor 2 binding // inferred from electronic annotation 205631_at NM_014749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014749.1 /DEF=Homo sapiens KIAA0586 gene product (KIAA0586), mRNA. /FEA=mRNA /GEN=KIAA0586 /PROD=KIAA0586 gene product /DB_XREF=gi:7662189 /UG=Hs.77724 KIAA0586 gene product /FL=gb:AB011158.1 gb:NM_014749.1 NM_014749 KIAA0586 KIAA0586 9786 NM_001244189 /// NM_001244190 /// NM_001244191 /// NM_001244192 /// NM_001244193 /// NM_014749 /// XM_006720336 /// XM_006720337 /// XM_006720338 /// XM_006720339 /// XM_006720340 /// XM_006720341 /// XM_006720342 /// XM_006720343 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0070201 // regulation of establishment of protein localization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from direct assay 205632_s_at NM_003558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003558.1 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type I, beta (PIP5K1B), mRNA. /FEA=mRNA /GEN=PIP5K1B /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeI, beta /DB_XREF=gi:4505816 /UG=Hs.78406 phosphatidylinositol-4-phosphate 5-kinase, type I, beta /FL=gb:NM_003558.1 NM_003558 phosphatidylinositol-4-phosphate 5-kinase, type I, beta PIP5K1B 8395 NM_001031687 /// NM_001278253 /// NM_003558 /// XM_005252261 /// XM_005252262 /// XM_006717300 /// XM_006717301 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // non-traceable author statement 0001931 // uropod // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 205633_s_at NM_000688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000688.1 /DEF=Homo sapiens aminolevulinate, delta-, synthase 1 (ALAS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ALAS1 /PROD=aminolevulinate, delta-, synthase 1 /DB_XREF=gi:4502024 /UG=Hs.78712 aminolevulinate, delta-, synthase 1 /FL=gb:NM_000688.1 NM_000688 aminolevulinate, delta-, synthase 1 ALAS1 211 NM_000688 /// NM_199166 /// XM_005264944 /// XM_005264945 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003870 // 5-aminolevulinate synthase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 205634_x_at NM_024298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024298.1 /DEF=Homo sapiens malignant cell expression-enhanced genetumor progression-enhanced gene (LENG4), mRNA. /FEA=mRNA /GEN=LENG4 /PROD=malignant cell expression-enhanced genetumorprogression-enhanced gene /DB_XREF=gi:13236521 /UG=Hs.78768 malignant cell expression-enhanced genetumor progression-enhanced gene /FL=gb:BC002598.1 gb:NM_024298.1 NM_024298 zinc finger, DHHC-type containing 24 ZDHHC24 254359 NM_207340 /// XM_005273873 /// XM_005273874 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205635_at NM_003947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003947.1 /DEF=Homo sapiens huntingtin-associated protein interacting protein (duo) (HAPIP), mRNA. /FEA=mRNA /GEN=HAPIP /PROD=huntingtin-associated protein interactingprotein /DB_XREF=gi:4504334 /UG=Hs.8004 huntingtin-associated protein interacting protein (duo) /FL=gb:U94190.1 gb:NM_003947.1 NM_003947 kalirin, RhoGEF kinase KALRN 8997 NM_001024660 /// NM_003947 /// NM_007064 /// NR_028136 /// XM_006713810 /// XM_006713811 /// XM_006713812 /// XM_006713813 /// XM_006713814 /// XM_006713815 /// XM_006713816 /// XM_006713817 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205636_at AF036269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF036269.1 /DEF=Homo sapiens EEN-B2-L1 mRNA, complete cds. /FEA=mRNA /GEN=EEN-B2-L1 /PROD=EEN-B2-L1 /DB_XREF=gi:2921409 /UG=Hs.80315 SH3-domain GRB2-like 3 /FL=gb:AF036269.1 gb:AF036270.1 gb:AF036271.1 gb:NM_003027.1 AF036269 SH3-domain GRB2-like 3 SH3GL3 6457 NM_003027 /// NR_026799 /// XM_006720638 /// XM_006720639 /// XM_006720640 /// XR_429469 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 205637_s_at NM_003027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003027.1 /DEF=Homo sapiens SH3-domain GRB2-like 3 (SH3GL3), mRNA. /FEA=mRNA /GEN=SH3GL3 /PROD=SH3-domain GRB2-like 3 /DB_XREF=gi:4506932 /UG=Hs.80315 SH3-domain GRB2-like 3 /FL=gb:AF036269.1 gb:AF036270.1 gb:AF036271.1 gb:NM_003027.1 NM_003027 SH3-domain GRB2-like 3 SH3GL3 6457 NM_003027 /// NR_026799 /// XM_006720638 /// XM_006720639 /// XM_006720640 /// XR_429469 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 205638_at NM_001704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001704.1 /DEF=Homo sapiens brain-specific angiogenesis inhibitor 3 (BAI3), mRNA. /FEA=mRNA /GEN=BAI3 /PROD=brain-specific angiogenesis inhibitor 3 /DB_XREF=gi:4502358 /UG=Hs.8074 brain-specific angiogenesis inhibitor 3 /FL=gb:AB005299.1 gb:NM_001704.1 NM_001704 brain-specific angiogenesis inhibitor 3 BAI3 577 NM_001704 /// XM_005248752 /// XM_005248753 /// XM_006715534 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205639_at NM_001637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001637.1 /DEF=Homo sapiens acyloxyacyl hydrolase (neutrophil) (AOAH), mRNA. /FEA=mRNA /GEN=AOAH /PROD=acyloxyacyl hydrolase precursor /DB_XREF=gi:4502114 /UG=Hs.82542 acyloxyacyl hydrolase (neutrophil) /FL=gb:M62840.1 gb:NM_001637.1 NM_001637 acyloxyacyl hydrolase (neutrophil) AOAH 313 NM_001177506 /// NM_001177507 /// NM_001637 0006629 // lipid metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0008653 // lipopolysaccharide metabolic process // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0004465 // lipoprotein lipase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0050528 // acyloxyacyl hydrolase activity // inferred from electronic annotation 205640_at NM_000694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000694.1 /DEF=Homo sapiens aldehyde dehydrogenase 3 family, member B1 (ALDH3B1), mRNA. /FEA=mRNA /GEN=ALDH3B1 /PROD=aldehyde dehydrogenase 3B1 /DB_XREF=gi:4502042 /UG=Hs.83155 aldehyde dehydrogenase 3 family, member B1 /FL=gb:NM_000694.1 gb:U10868.1 NM_000694 aldehyde dehydrogenase 3 family, member B1 ALDH3B1 221 NM_000694 /// NM_001030010 /// NM_001161473 /// NM_001290058 /// NM_001290059 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0046185 // aldehyde catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 205641_s_at NM_003789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003789.1 /DEF=Homo sapiens TNFRSF1A-associated via death domain (TRADD), mRNA. /FEA=mRNA /GEN=TRADD /PROD=TNFRSF1A-associated via death domain /DB_XREF=gi:13378136 /UG=Hs.89862 TNFRSF1A-associated via death domain /FL=gb:BC004491.1 gb:NM_003789.1 NM_003789 TNFRSF1A-associated via death domain TRADD 8717 NM_003789 /// NM_153425 /// XM_005256213 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction 205642_at NM_007018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007018.1 /DEF=Homo sapiens centrosomal protein 1 (CEP1), mRNA. /FEA=mRNA /GEN=CEP1 /PROD=centrosomal protein 1 /DB_XREF=gi:5901923 /UG=Hs.97437 centrosomal protein 1 /FL=gb:AF083322.1 gb:NM_007018.1 NM_007018 centriolin CNTRL 11064 NM_007018 /// XM_005251679 /// XM_006716940 /// XM_006716941 /// XM_006716942 /// XM_006716943 /// XM_006716944 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205643_s_at NM_004576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004576.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform (PPP2R2B), mRNA. /FEA=mRNA /GEN=PPP2R2B /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit B (PR 52), beta isoform /DB_XREF=gi:4758953 /UG=Hs.7688 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform /FL=gb:NM_004576.1 NM_004576 protein phosphatase 2, regulatory subunit B, beta PPP2R2B 5521 NM_001271899 /// NM_001271900 /// NM_001271948 /// NM_181674 /// NM_181675 /// NM_181676 /// NM_181677 /// NM_181678 /// NR_073526 /// NR_073527 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 205644_s_at NM_003096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003096.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide G (SNRPG), mRNA. /FEA=mRNA /GEN=SNRPG /PROD=small nuclear ribonucleoprotein polypeptide G /DB_XREF=gi:4507132 /UG=Hs.77496 small nuclear ribonucleoprotein polypeptide G /FL=gb:BC000070.1 gb:NM_003096.1 NM_003096 small nuclear ribonucleoprotein polypeptide G SNRPG 6637 NM_003096 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // non-traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 205645_at NM_004726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004726.1 /DEF=Homo sapiens RALBP1 associated Eps domain containing 2 (REPS2), mRNA. /FEA=mRNA /GEN=REPS2 /PROD=RALBP1 associated Eps domain containing 2 /DB_XREF=gi:4758943 /UG=Hs.80667 RALBP1 associated Eps domain containing 2 /FL=gb:AF010233.1 gb:NM_004726.1 NM_004726 RALBP1 associated Eps domain containing 2 REPS2 9185 NM_001080975 /// NM_004726 /// XM_005274624 /// XM_005274625 /// XM_005274626 /// XM_006724523 0006461 // protein complex assembly // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205646_s_at NM_000280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000280.1 /DEF=Homo sapiens paired box gene 6 (aniridia, keratitis) (PAX6), mRNA. /FEA=mRNA /GEN=PAX6 /PROD=paired box gene 6, isoform a /DB_XREF=gi:4505614 /UG=Hs.89506 paired box gene 6 (aniridia, keratitis) /FL=gb:M93650.1 gb:NM_000280.1 NM_000280 paired box 6 PAX6 5080 NM_000280 /// NM_001127612 /// NM_001258462 /// NM_001258463 /// NM_001258464 /// NM_001258465 /// NM_001604 /// XM_005252954 /// XM_005252955 /// XM_005252956 /// XM_005252957 /// XM_005252958 /// XM_006718244 /// XM_006718245 /// XM_006718246 0001568 // blood vessel development // inferred from mutant phenotype /// 0001654 // eye development // traceable author statement /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0003309 // type B pancreatic cell differentiation // inferred from electronic annotation /// 0003322 // pancreatic A cell development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009887 // organ morphogenesis // traceable author statement /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0021543 // pallium development // inferred from electronic annotation /// 0021778 // oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0021797 // forebrain anterior/posterior pattern specification // inferred from electronic annotation /// 0021798 // forebrain dorsal/ventral pattern formation // inferred from electronic annotation /// 0021902 // commitment of neuronal cell to specific neuron type in forebrain // inferred from electronic annotation /// 0021905 // forebrain-midbrain boundary formation // inferred from electronic annotation /// 0021912 // regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification // inferred from electronic annotation /// 0021913 // regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification // inferred from electronic annotation /// 0021918 // regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0032808 // lacrimal gland development // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0042660 // positive regulation of cell fate specification // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // non-traceable author statement /// 0048708 // astrocyte differentiation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0061072 // iris morphogenesis // inferred from mutant phenotype /// 0061303 // cornea development in camera-type eye // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003680 // AT DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 205647_at NM_002879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002879.1 /DEF=Homo sapiens RAD52 (S. cerevisiae) homolog (RAD52), mRNA. /FEA=mRNA /GEN=RAD52 /PROD=RAD52 (S. cerevisiae) homolog /DB_XREF=gi:4506394 /UG=Hs.89571 RAD52 (S. cerevisiae) homolog /FL=gb:NM_002879.1 gb:L33262.1 gb:U12134.1 gb:U27516.1 NM_002879 RAD52 homolog (S. cerevisiae) RAD52 5893 NM_001297419 /// NM_001297420 /// NM_001297421 /// NM_001297422 /// NM_134422 /// NM_134423 /// NM_134424 /// NR_123713 /// XM_005253720 /// XM_005253721 /// XM_005253725 /// XM_005253727 /// XM_006718995 /// XM_006718996 /// XM_006718997 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from mutant phenotype /// 0006312 // mitotic recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 205648_at NM_003391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003391.1 /DEF=Homo sapiens wingless-type MMTV integration site family member 2 (WNT2), mRNA. /FEA=mRNA /GEN=WNT2 /PROD=wingless-type MMTV integration site familymember 2 /DB_XREF=gi:4507926 /UG=Hs.89791 wingless-type MMTV integration site family member 2 /FL=gb:NM_003391.1 NM_003391 wingless-type MMTV integration site family member 2 WNT2 7472 NM_003391 /// NR_024047 /// XM_006716109 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation /// 0060492 // lung induction // inferred from electronic annotation /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from sequence or structural similarity /// 0061180 // mammary gland epithelium development // inferred from expression pattern /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0048018 // receptor agonist activity // inferred by curator 205649_s_at NM_000508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000508.2 /DEF=Homo sapiens fibrinogen, A alpha polypeptide (FGA), transcript variant alpha-E, mRNA. /FEA=mRNA /GEN=FGA /PROD=fibrinogen, alpha chain, isoform alpha-Epreproprotein /DB_XREF=gi:11761627 /UG=Hs.90765 fibrinogen, A alpha polypeptide /FL=gb:NM_000508.2 NM_000508 fibrinogen alpha chain FGA 2243 NM_000508 /// NM_021871 0002576 // platelet degranulation // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from direct assay /// 0045921 // positive regulation of exocytosis // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051258 // protein polymerization // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // inferred from direct assay /// 0072377 // blood coagulation, common pathway // inferred from mutant phenotype /// 0090277 // positive regulation of peptide hormone secretion // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000261 // negative regulation of blood coagulation, common pathway // traceable author statement /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from direct assay /// 0005198 // structural molecule activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from direct assay 205650_s_at NM_021871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021871.1 /DEF=Homo sapiens fibrinogen, A alpha polypeptide (FGA), transcript variant alpha, mRNA. /FEA=mRNA /GEN=FGA /PROD=fibrinogen, alpha chain, isoform alphapreproprotein /DB_XREF=gi:11761628 /UG=Hs.90765 fibrinogen, A alpha polypeptide /FL=gb:NM_021871.1 gb:J00127.1 gb:J00128.1 NM_021871 fibrinogen alpha chain FGA 2243 NM_000508 /// NM_021871 0002576 // platelet degranulation // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from direct assay /// 0045921 // positive regulation of exocytosis // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051258 // protein polymerization // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // inferred from direct assay /// 0072377 // blood coagulation, common pathway // inferred from mutant phenotype /// 0090277 // positive regulation of peptide hormone secretion // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000261 // negative regulation of blood coagulation, common pathway // traceable author statement /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from direct assay /// 0005198 // structural molecule activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from direct assay 205651_x_at NM_007023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007023.1 /DEF=Homo sapiens cAMP-regulated guanine nucleotide exchange factor II (CAMP-GEFII), mRNA. /FEA=mRNA /GEN=CAMP-GEFII /PROD=cAMP-regulated guanine nucleotide exchangefactor II /DB_XREF=gi:5901913 /UG=Hs.91971 cAMP-regulated guanine nucleotide exchange factor II /FL=gb:U78516.1 gb:NM_007023.1 NM_007023 Rap guanine nucleotide exchange factor (GEF) 4 RAPGEF4 11069 NM_001100397 /// NM_001282899 /// NM_001282900 /// NM_001282901 /// NM_007023 /// XM_005246246 /// XM_006712205 /// XM_006712206 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032318 // regulation of Ras GTPase activity // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from sequence or structural similarity /// 0030552 // cAMP binding // inferred from sequence or structural similarity 205652_s_at NM_012263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012263.1 /DEF=Homo sapiens tubulin tyrosine ligase-like 1 (TTLL1), mRNA. /FEA=mRNA /GEN=TTLL1 /PROD=tubulin tyrosine ligase-like 1 /DB_XREF=gi:11068134 /UG=Hs.94958 tubulin tyrosine ligase-like 1 /FL=gb:NM_012263.1 gb:AF104927.1 gb:AL136687.1 NM_012263 tubulin tyrosine ligase-like family, member 1 TTLL1 25809 NM_001008572 /// NM_012263 /// NR_027779 /// XM_006724225 0003351 // epithelial cilium movement // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018095 // protein polyglutamylation // traceable author statement /// 0044782 // cilium organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0070740 // tubulin-glutamic acid ligase activity // traceable author statement 205653_at NM_001911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001911.1 /DEF=Homo sapiens cathepsin G (CTSG), mRNA. /FEA=mRNA /GEN=CTSG /PROD=cathepsin G /DB_XREF=gi:4503148 /UG=Hs.100764 cathepsin G /FL=gb:M16117.1 gb:NM_001911.1 NM_001911 cathepsin G CTSG 1511 NM_001911 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // not recorded /// 0070946 // neutrophil mediated killing of gram-positive bacterium // not recorded 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205654_at NM_000715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000715.1 /DEF=Homo sapiens complement component 4-binding protein, alpha (C4BPA), mRNA. /FEA=mRNA /GEN=C4BPA /PROD=complement component 4-binding protein, alpha /DB_XREF=gi:4502502 /UG=Hs.1012 complement component 4-binding protein, alpha /FL=gb:M31452.1 gb:NM_000715.1 NM_000715 complement component 4 binding protein, alpha C4BPA 722 NM_000715 /// XM_005273251 /// XM_005273252 0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1903027 // regulation of opsonization // inferred by curator 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0044216 // other organism cell // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 205655_at NM_002393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002393.1 /DEF=Homo sapiens mouse double minute 4, human homolog of; p53-binding protein (MDM4), mRNA. /FEA=mRNA /GEN=MDM4 /PROD=mouse double minute 4, human homolog of /DB_XREF=gi:4505138 /UG=Hs.101874 mouse double minute 4, human homolog of; p53-binding protein /FL=gb:AF007111.1 gb:NM_002393.1 NM_002393 MDM4, p53 regulator MDM4 4194 NM_001204171 /// NM_001204172 /// NM_001278516 /// NM_001278517 /// NM_001278518 /// NM_001278519 /// NM_002393 /// XM_006711328 /// XM_006711329 /// XR_241079 /// XR_426774 /// XR_426775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0008283 // cell proliferation // inferred from expression pattern /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from expression pattern /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045023 // G0 to G1 transition // inferred from expression pattern /// 0050821 // protein stabilization // inferred from expression pattern /// 0071157 // negative regulation of cell cycle arrest // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205656_at NM_014459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014459.1 /DEF=Homo sapiens protocadherin 17 (PCDH17), mRNA. /FEA=mRNA /GEN=PCDH17 /PROD=protocadherin 17 /DB_XREF=gi:7657446 /UG=Hs.106511 protocadherin 17 /FL=gb:AF029343.1 gb:NM_014459.1 NM_014459 protocadherin 17 PCDH17 27253 NM_001040429 /// NM_014459 /// XM_005266357 /// XM_005266358 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205657_at NM_012205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012205.1 /DEF=Homo sapiens 3-hydroxyanthranilate 3,4-dioxygenase (HAAO), mRNA. /FEA=mRNA /GEN=HAAO /PROD=3-hydroxyanthranilate 3,4-dioxygenase /DB_XREF=gi:6912405 /UG=Hs.108441 3-hydroxyanthranilate 3,4-dioxygenase /FL=gb:NM_012205.1 NM_012205 3-hydroxyanthranilate 3,4-dioxygenase HAAO 23498 NM_012205 /// XM_005264230 0006569 // tryptophan catabolic process // traceable author statement /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from direct assay /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // non-traceable author statement /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from direct assay /// 0046874 // quinolinate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070050 // neuron cellular homeostasis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000334 // 3-hydroxyanthranilate 3,4-dioxygenase activity // inferred from direct assay /// 0000334 // 3-hydroxyanthranilate 3,4-dioxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205658_s_at NM_003086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003086.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 4, 190kD (SNAPC4), mRNA. /FEA=mRNA /GEN=SNAPC4 /PROD=small nuclear RNA activating complex,polypeptide 4, 190kD /DB_XREF=gi:4507106 /UG=Hs.113265 small nuclear RNA activating complex, polypeptide 4, 190kD /FL=gb:AF032387.1 gb:NM_003086.1 NM_003086 small nuclear RNA activating complex, polypeptide 4, 190kDa SNAPC4 6621 NM_003086 /// XM_005266096 /// XM_006717241 /// XM_006717242 /// XM_006717243 /// XM_006717244 /// XR_428535 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042795 // snRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0042796 // snRNA transcription from RNA polymerase III promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // traceable author statement /// 0019185 // snRNA-activating protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 205659_at NM_014707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014707.1 /DEF=Homo sapiens histone deacetylase 7B (HDAC7B-PENDING), mRNA. /FEA=mRNA /GEN=HDAC7B-PENDING /PROD=histone deacetylase 7B /DB_XREF=gi:7662279 /UG=Hs.116753 histone deacetylase 7B /FL=gb:AB018287.1 gb:NM_014707.1 NM_014707 histone deacetylase 9 HDAC9 9734 NM_001204144 /// NM_001204145 /// NM_001204146 /// NM_001204147 /// NM_001204148 /// NM_014707 /// NM_058176 /// NM_058177 /// NM_178423 /// NM_178425 /// XM_006715802 /// XM_006715803 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0030183 // B cell differentiation // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0034983 // peptidyl-lysine deacetylation // inferred from direct assay /// 0042113 // B cell activation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048742 // regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051153 // regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from mutant phenotype 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 205660_at NM_003733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003733.1 /DEF=Homo sapiens 2-5oligoadenylate synthetase-like (OASL), mRNA. /FEA=mRNA /GEN=OASL /PROD=2-5oligoadenylate synthetase-like /DB_XREF=gi:11321576 /UG=Hs.118633 2-5oligoadenylate synthetase-like /FL=gb:NM_003733.1 gb:AF063611.1 NM_003733 2'-5'-oligoadenylate synthetase-like OASL 8638 NM_001261825 /// NM_003733 /// NM_198213 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // traceable author statement 205661_s_at NM_025207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025207.1 /DEF=Homo sapiens hypothetical protein PP591 (PP591), mRNA. /FEA=mRNA /GEN=PP591 /PROD=hypothetical protein PP591 /DB_XREF=gi:13376805 /UG=Hs.118666 hypothetical protein PP591 /FL=gb:NM_025207.1 NM_025207 flavin adenine dinucleotide synthetase 1 FLAD1 80308 NM_001184891 /// NM_001184892 /// NM_025207 /// NM_201398 /// XM_005245502 /// XM_005245503 /// XM_006711557 /// XM_006711558 /// XM_006711559 /// XR_241098 /// XR_426798 0006747 // FAD biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003919 // FMN adenylyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 205662_at NM_015681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015681.1 /DEF=Homo sapiens B9 protein (B9), mRNA. /FEA=mRNA /GEN=B9 /PROD=B9 protein /DB_XREF=gi:7661535 /UG=Hs.11955 B9 protein /FL=gb:AB030506.1 gb:NM_015681.1 NM_015681 B9 protein domain 1 B9D1 27077 NM_001243473 /// NM_001243475 /// NM_015681 /// XM_005256605 /// XM_005256607 /// XM_005256608 /// XM_005256609 /// XM_005256610 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008158 // hedgehog receptor activity // inferred from sequence or structural similarity 205663_at NM_020528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020528.1 /DEF=Homo sapiens poly(rC)-binding protein 3 (PCBP3), mRNA. /FEA=mRNA /GEN=PCBP3 /PROD=poly(rC)-binding protein 3 /DB_XREF=gi:10092616 /UG=Hs.121241 poly(rC)-binding protein 3 /FL=gb:NM_020528.1 gb:AF176329.1 NM_020528 poly(rC) binding protein 3 PCBP3 54039 NM_001130141 /// NM_020528 0016071 // mRNA metabolic process // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 205664_at NM_012311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012311.1 /DEF=Homo sapiens antigenic determinant of recA protein (mouse) homolog (KIN), mRNA. /FEA=mRNA /GEN=KIN /PROD=HsKin17 protein /DB_XREF=gi:13124882 /UG=Hs.123647 antigenic determinant of recA protein (mouse) homolog /FL=gb:NM_012311.1 NM_012311 KIN, antigenic determinant of recA protein homolog (mouse) KIN 22944 NM_012311 /// NR_045609 /// NR_045610 /// XM_006717434 /// XM_006717435 0006260 // DNA replication // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205665_at NM_006675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006675.1 /DEF=Homo sapiens tetraspan transmembrane 4 super family (NET-5), mRNA. /FEA=mRNA /GEN=NET-5 /PROD=tetraspan transmembrane 4 super family /DB_XREF=gi:5729940 /UG=Hs.129826 tetraspan transmembrane 4 super family /FL=gb:AF089749.1 gb:NM_006675.1 NM_006675 tetraspanin 9 TSPAN9 10867 NM_001168320 /// NM_006675 /// XM_006718956 /// XM_006718957 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 205666_at NM_002021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002021.1 /DEF=Homo sapiens flavin containing monooxygenase 1 (FMO1), mRNA. /FEA=mRNA /GEN=FMO1 /PROD=flavin containing monooxygenase 1 /DB_XREF=gi:4503754 /UG=Hs.1424 flavin containing monooxygenase 1 /FL=gb:M64082.1 gb:NM_002021.1 NM_002021 flavin containing monooxygenase 1 FMO1 2326 NM_001282692 /// NM_001282693 /// NM_001282694 /// NM_002021 /// XM_005245037 /// XM_005245038 /// XM_006711241 /// XM_006711242 0006082 // organic acid metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070995 // NADPH oxidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0004499 // N,N-dimethylaniline monooxygenase activity // inferred from direct assay /// 0004499 // N,N-dimethylaniline monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 205667_at NM_000553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000553.1 /DEF=Homo sapiens Werner syndrome (WRN), mRNA. /FEA=mRNA /GEN=WRN /PROD=Werner syndrome protein /DB_XREF=gi:5739523 /UG=Hs.150477 Werner syndrome /FL=gb:AF091214.1 gb:NM_000553.1 NM_000553 Werner syndrome, RecQ helicase-like WRN 7486 NM_000553 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000731 // DNA synthesis involved in DNA repair // inferred from direct assay /// 0001302 // replicative cell aging // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007568 // aging // non-traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from direct assay /// 0010225 // response to UV-C // inferred from direct assay /// 0010259 // multicellular organismal aging // inferred from mutant phenotype /// 0031297 // replication fork processing // inferred from direct assay /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0032066 // nucleolus to nucleoplasm transport // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0040009 // regulation of growth rate // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from genetic interaction /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0032389 // MutLalpha complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000403 // Y-form DNA binding // inferred from direct assay /// 0000405 // bubble DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0009378 // four-way junction helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0030145 // manganese ion binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043138 // 3'-5' DNA helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051880 // G-quadruplex DNA binding // inferred from direct assay 205668_at NM_002349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002349.1 /DEF=Homo sapiens lymphocyte antigen 75 (LY75), mRNA. /FEA=mRNA /GEN=LY75 /PROD=lymphocyte antigen 75 /DB_XREF=gi:4505052 /UG=Hs.153563 lymphocyte antigen 75 /FL=gb:AF011333.1 gb:AF064827.1 gb:NM_002349.1 NM_002349 lymphocyte antigen 75 LY75 4065 NM_002349 0006897 // endocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 205669_at NM_004540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004540.1 /DEF=Homo sapiens neural cell adhesion molecule 2 (NCAM2), mRNA. /FEA=mRNA /GEN=NCAM2 /PROD=neural cell adhesion molecule 2 /DB_XREF=gi:4758763 /UG=Hs.177691 neural cell adhesion molecule 2 /FL=gb:U75330.1 gb:NM_004540.1 NM_004540 neural cell adhesion molecule 2 NCAM2 4685 NM_004540 /// XM_005260988 /// XM_006724007 /// XM_006724008 /// XM_006724009 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation 205670_at NM_004861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004861.1 /DEF=Homo sapiens cerebroside (3-phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase (CST), mRNA. /FEA=mRNA /GEN=CST /PROD=galactosylceramide sulfotransferase /DB_XREF=gi:4758087 /UG=Hs.17958 cerebroside (3-phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase /FL=gb:D88667.1 gb:NM_004861.1 NM_004861 galactose-3-O-sulfotransferase 1 GAL3ST1 9514 NM_004861 /// XM_005261848 /// XM_005261853 /// XM_005261856 0006487 // protein N-linked glycosylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006682 // galactosylceramide biosynthetic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0001733 // galactosylceramide sulfotransferase activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 205671_s_at NM_002120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002120.1 /DEF=Homo sapiens major histocompatibility complex, class II, DO beta (HLA-DOB), mRNA. /FEA=mRNA /GEN=HLA-DOB /PROD=major histocompatibility complex, class II, DObeta /DB_XREF=gi:4504402 /UG=Hs.1802 major histocompatibility complex, class II, DO beta /FL=gb:M26040.1 gb:NM_002120.1 NM_002120 major histocompatibility complex, class II, DO beta HLA-DOB 3112 NM_002120 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002587 // negative regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement 205672_at NM_000380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000380.1 /DEF=Homo sapiens xeroderma pigmentosum, complementation group A (XPA), mRNA. /FEA=mRNA /GEN=XPA /PROD=xeroderma pigmentosum, complementation group A /DB_XREF=gi:4507936 /UG=Hs.192803 xeroderma pigmentosum, complementation group A /FL=gb:NM_000380.1 NM_000380 xeroderma pigmentosum, complementation group A XPA 7507 NM_000380 /// NR_027302 /// XM_006717278 /// XR_428536 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205673_s_at NM_024087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024087.1 /DEF=Homo sapiens DKFZP564L0862 protein (DKFZP564L0862), mRNA. /FEA=mRNA /GEN=DKFZP564L0862 /PROD=hypothetical protein FLJ20636 /DB_XREF=gi:13443013 /UG=Hs.19404 DKFZP564L0862 protein /FL=gb:NM_024087.1 NM_024087 ankyrin repeat and SOCS box containing 9 ASB9 140462 NM_001031739 /// NM_001168530 /// NM_001168531 /// NM_024087 /// XM_005274446 /// XM_005274448 /// XM_006724465 /// XM_006724466 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205674_x_at NM_001680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001680.2 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 2 (FXYD2), transcript variant a, mRNA. /FEA=mRNA /GEN=FXYD2 /PROD=FXYD domain-containing ion transport regulator2, isoform 1 /DB_XREF=gi:11125765 /UG=Hs.19520 FXYD domain-containing ion transport regulator 2 /FL=gb:NM_001680.2 gb:AF241236.1 gb:U50743.1 NM_001680 FXYD domain containing ion transport regulator 2 FXYD2 486 NM_001127489 /// NM_001680 /// NM_021603 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 205675_at AI623321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI623321 /FEA=EST /DB_XREF=gi:4648246 /DB_XREF=est:ts80d03.x1 /CLONE=IMAGE:2237573 /UG=Hs.195799 microsomal triglyceride transfer protein (large polypeptide, 88kD) /FL=gb:NM_000253.1 AI623321 microsomal triglyceride transfer protein MTTP 4547 NM_000253 /// XM_005263025 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005319 // lipid transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205676_at NM_000785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000785.1 /DEF=Homo sapiens cytochrome P450, subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase), polypeptide 1 (CYP27B1), mRNA. /FEA=mRNA /GEN=CYP27B1 /PROD=cytochrome P450, subfamily XXVIIB(25-hydroxyvitamin D-1-alpha-hydroxylase), polypeptide 1 /DB_XREF=gi:4503212 /UG=Hs.199270 cytochrome P450, subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase), polypeptide 1 /FL=gb:AB005989.1 gb:AF020192.1 gb:AB005038.1 gb:NM_000785.1 gb:AF246895.1 NM_000785 cytochrome P450, family 27, subfamily B, polypeptide 1 CYP27B1 1594 NM_000785 0006766 // vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0008202 // steroid metabolic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010956 // negative regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030282 // bone mineralization // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030500 // regulation of bone mineralization // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0033280 // response to vitamin D // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0036378 // calcitriol biosynthetic process from calciol // inferred from direct assay /// 0042359 // vitamin D metabolic process // inferred from direct assay /// 0042359 // vitamin D metabolic process // traceable author statement /// 0042369 // vitamin D catabolic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0055074 // calcium ion homeostasis // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from mutant phenotype /// 0070564 // positive regulation of vitamin D receptor signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004498 // calcidiol 1-monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205677_s_at NM_005887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005887.1 /DEF=Homo sapiens deleted in lymphocytic leukemia, 1 (DLEU1), mRNA. /FEA=mRNA /GEN=DLEU1 /PROD=deleted in lymphocytic leukemia, 1 /DB_XREF=gi:5031858 /UG=Hs.20149 deleted in lymphocytic leukemia, 1 /FL=gb:NM_005887.1 NM_005887 deleted in lymphocytic leukemia 1 (non-protein coding) DLEU1 10301 NM_005887 /// NR_002605 /// NR_109973 /// NR_109974 0005515 // protein binding // inferred from physical interaction 205678_at NM_004644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004644.1 /DEF=Homo sapiens adaptor-related protein complex 3, beta 2 subunit (AP3B2), mRNA. /FEA=mRNA /GEN=AP3B2 /PROD=adaptor-related protein complex 3, beta 2subunit /DB_XREF=gi:4758759 /UG=Hs.21022 adaptor-related protein complex 3, beta 2 subunit /FL=gb:U37673.1 gb:AF022152.1 gb:NM_004644.1 NM_004644 adaptor-related protein complex 3, beta 2 subunit AP3B2 8120 NM_001278511 /// NM_001278512 /// NM_004644 /// XM_006720704 /// XM_006720705 /// XM_006720706 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from electronic annotation /// 0030137 // COPI-coated vesicle // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation 205679_x_at NM_013227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013227.1 /DEF=Homo sapiens aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) (AGC1), transcript variant 2, mRNA. /FEA=mRNA /GEN=AGC1 /PROD=aggrecan 1, isoform 2 precursor /DB_XREF=gi:6995993 /UG=Hs.2159 aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) /FL=gb:NM_013227.1 NM_013227 aggrecan ACAN 176 NM_001135 /// NM_013227 /// XM_006720419 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030166 // proteoglycan biosynthetic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205680_at NM_002425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002425.1 /DEF=Homo sapiens matrix metalloproteinase 10 (stromelysin 2) (MMP10), mRNA. /FEA=mRNA /GEN=MMP10 /PROD=matrix metalloproteinase 10 preproprotein /DB_XREF=gi:4505204 /UG=Hs.2258 matrix metalloproteinase 10 (stromelysin 2) /FL=gb:BC002591.1 gb:NM_002425.1 NM_002425 matrix metallopeptidase 10 (stromelysin 2) MMP10 4319 NM_002425 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205681_at NM_004049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004049.1 /DEF=Homo sapiens BCL2-related protein A1 (BCL2A1), mRNA. /FEA=mRNA /GEN=BCL2A1 /PROD=BCL2-related protein A1 /DB_XREF=gi:4757839 /UG=Hs.227817 BCL2-related protein A1 /FL=gb:U27467.1 gb:U29680.1 gb:NM_004049.1 NM_004049 BCL2-related protein A1 BCL2A1 597 NM_001114735 /// NM_004049 0006915 // apoptotic process // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // not recorded 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded /// 0051400 // BH domain binding // inferred from electronic annotation 205682_x_at NM_019101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019101.1 /DEF=Homo sapiens apolipoprotein M (G3A), mRNA. /FEA=mRNA /GEN=G3A /PROD=apolipoprotein M /DB_XREF=gi:9506706 /UG=Hs.247129 apolipoprotein M /FL=gb:AF118393.3 gb:NM_019101.1 NM_019101 apolipoprotein M APOM 55937 NM_001256169 /// NM_019101 /// NR_045828 /// XM_006715150 /// XM_006725493 /// XM_006725707 /// XM_006725824 /// XM_006725916 /// XM_006726009 /// XM_006726104 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034445 // negative regulation of plasma lipoprotein particle oxidation // inferred from direct assay /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred by curator /// 0043691 // reverse cholesterol transport // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034365 // discoidal high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005319 // lipid transporter activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay 205683_x_at NM_003294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003294.2 /DEF=Homo sapiens tryptase beta 1 (TPSB1), mRNA. /FEA=mRNA /GEN=TPSB1 /PROD=beta tryptase 1 precursor /DB_XREF=gi:13775594 /UG=Hs.250700 tryptase beta 1 /FL=gb:NM_003294.2 gb:M37488.1 NM_003294 tryptase alpha/beta 1 TPSAB1 7177 NM_003294 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205684_s_at NM_017925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017925.1 /DEF=Homo sapiens hypothetical protein FLJ20686 (FLJ20686), mRNA. /FEA=mRNA /GEN=FLJ20686 /PROD=hypothetical protein FLJ20686 /DB_XREF=gi:8923616 /UG=Hs.271480 hypothetical protein FLJ20686 /FL=gb:NM_017925.1 NM_017925 DENN/MADD domain containing 4C DENND4C 55667 NM_017925 /// NR_073201 /// XM_006716804 /// XM_006716805 /// XM_006716806 /// XM_006716807 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 205685_at BG236280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG236280 /FEA=EST /DB_XREF=gi:12750052 /DB_XREF=est:naf24d07.x1 /CLONE=IMAGE:4141884 /UG=Hs.27954 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) /FL=gb:U04343.1 gb:NM_006889.1 BG236280 CD86 molecule CD86 942 NM_001206924 /// NM_001206925 /// NM_006889 /// NM_175862 /// NM_176892 /// XM_005247905 0001878 // response to yeast // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002668 // negative regulation of T cell anergy // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042110 // T cell activation // inferred by curator /// 0042113 // B cell activation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043017 // positive regulation of lymphotoxin A biosynthetic process // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045404 // positive regulation of interleukin-4 biosynthetic process // non-traceable author statement /// 0045630 // positive regulation of T-helper 2 cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement 205686_s_at NM_006889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006889.1 /DEF=Homo sapiens CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) (CD86), mRNA. /FEA=mRNA /GEN=CD86 /PROD=CD86 antigen (CD28 antigen ligand 2, B7-2antigen) /DB_XREF=gi:5901919 /UG=Hs.27954 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) /FL=gb:U04343.1 gb:NM_006889.1 NM_006889 CD86 molecule CD86 942 NM_001206924 /// NM_001206925 /// NM_006889 /// NM_175862 /// NM_176892 /// XM_005247905 0001878 // response to yeast // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002668 // negative regulation of T cell anergy // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042110 // T cell activation // inferred by curator /// 0042113 // B cell activation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043017 // positive regulation of lymphotoxin A biosynthetic process // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045404 // positive regulation of interleukin-4 biosynthetic process // non-traceable author statement /// 0045630 // positive regulation of T-helper 2 cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement 205687_at NM_019116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019116.1 /DEF=Homo sapiens similar to ubiquitin binding protein (UBPH), mRNA. /FEA=mRNA /GEN=UBPH /PROD=similar to ubiquitin binding protein /DB_XREF=gi:9507222 /UG=Hs.288620 similar to ubiquitin binding protein /FL=gb:NM_019116.1 NM_019116 ubiquitin family domain containing 1 UBFD1 56061 NM_019116 /// XM_006721064 /// XR_429678 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205688_at NM_003223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003223.1 /DEF=Homo sapiens transcription factor AP-4 (activating enhancer-binding protein 4) (TFAP4), mRNA. /FEA=mRNA /GEN=TFAP4 /PROD=transcription factor AP-4 (activatingenhancer-binding protein 4) /DB_XREF=gi:4507446 /UG=Hs.3005 transcription factor AP-4 (activating enhancer-binding protein 4) /FL=gb:NM_003223.1 NM_003223 transcription factor AP-4 (activating enhancer binding protein 4) TFAP4 7023 NM_003223 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // non-traceable author statement /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from mutant phenotype /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 2001269 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 205689_at NM_014801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014801.1 /DEF=Homo sapiens KIAA0435 gene product (KIAA0435), mRNA. /FEA=mRNA /GEN=KIAA0435 /PROD=KIAA0435 gene product /DB_XREF=gi:7662119 /UG=Hs.31438 KIAA0435 gene product /FL=gb:AB007895.1 gb:NM_014801.1 NM_014801 pecanex-like 2 (Drosophila) PCNXL2 80003 NM_014801 /// NM_024938 /// XM_005273272 /// XM_006711816 /// XR_247042 /// XR_426918 /// XR_426919 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation 205690_s_at NM_003910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003910.1 /DEF=Homo sapiens maternal G10 transcript (G10), mRNA. /FEA=mRNA /GEN=G10 /PROD=maternal G10 transcript /DB_XREF=gi:4503836 /UG=Hs.330310 maternal G10 transcript /FL=gb:NM_003910.1 gb:U11861.1 NM_003910 BUD31 homolog (S. cerevisiae) BUD31 8896 NM_003910 /// XM_005250670 /// XM_005250671 /// XM_005250672 /// XM_005250673 /// XM_005250674 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 205691_at NM_004209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004209.2 /DEF=Homo sapiens synaptogyrin 3 (SYNGR3), mRNA. /FEA=mRNA /GEN=SYNGR3 /PROD=synaptogyrin 3 /DB_XREF=gi:6631111 /UG=Hs.6467 synaptogyrin 3 /FL=gb:NM_004209.2 NM_004209 synaptogyrin 3 SYNGR3 9143 NM_004209 0021762 // substantia nigra development // inferred from expression pattern /// 0032411 // positive regulation of transporter activity // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 205692_s_at NM_001775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001775.1 /DEF=Homo sapiens CD38 antigen (p45) (CD38), mRNA. /FEA=mRNA /GEN=CD38 /PROD=CD38 antigen (p45) /DB_XREF=gi:4502664 /UG=Hs.66052 CD38 antigen (p45) /FL=gb:D84276.1 gb:NM_001775.1 gb:M34461.1 NM_001775 CD38 molecule CD38 952 NM_001775 /// XR_241678 0001666 // response to hypoxia // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003953 // NAD+ nucleosidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0050135 // NAD(P)+ nucleosidase activity // inferred from electronic annotation 205693_at NM_006757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006757.1 /DEF=Homo sapiens troponin T3, skeletal, fast (TNNT3), mRNA. /FEA=mRNA /GEN=TNNT3 /PROD=troponin T3, skeletal, fast /DB_XREF=gi:5803202 /UG=Hs.73454 troponin T3, skeletal, fast /FL=gb:M21984.1 gb:NM_006757.1 NM_006757 troponin T type 3 (skeletal, fast) TNNT3 7140 NM_001042780 /// NM_001042781 /// NM_001042782 /// NM_006757 /// XM_006718288 /// XM_006718289 /// XM_006718290 /// XM_006718291 /// XM_006718292 /// XM_006718293 /// XM_006718294 /// XM_006718295 /// XM_006718296 /// XM_006718297 /// XM_006718298 /// XM_006718299 /// XM_006718300 /// XM_006718301 /// XM_006718302 0003009 // skeletal muscle contraction // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0043462 // regulation of ATPase activity // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005523 // tropomyosin binding // inferred from direct assay /// 0005523 // tropomyosin binding // inferred from mutant phenotype /// 0030172 // troponin C binding // inferred from physical interaction /// 0030899 // calcium-dependent ATPase activity // inferred from direct assay /// 0031013 // troponin I binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from direct assay 205694_at NM_000550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000550.1 /DEF=Homo sapiens tyrosinase-related protein 1 (TYRP1), mRNA. /FEA=mRNA /GEN=TYRP1 /PROD=tyrosinase-related protein 1 /DB_XREF=gi:4507756 /UG=Hs.75219 tyrosinase-related protein 1 /FL=gb:NM_000550.1 NM_000550 tyrosinase-related protein 1 TYRP1 7306 NM_000550 /// XM_005251574 0006582 // melanin metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043438 // acetoacetic acid metabolic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // inferred from direct assay /// 0033162 // melanosome membrane // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from sequence or structural similarity 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016716 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 205695_at NM_006843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006843.1 /DEF=Homo sapiens serine dehydratase (SDS), mRNA. /FEA=mRNA /GEN=SDS /PROD=serine dehydratase /DB_XREF=gi:5803160 /UG=Hs.76751 serine dehydratase /FL=gb:J05037.1 gb:NM_006843.1 NM_006843 serine dehydratase SDS 10993 NM_006843 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006565 // L-serine catabolic process // inferred from direct assay /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from direct assay /// 0043200 // response to amino acid // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003941 // L-serine ammonia-lyase activity // inferred from direct assay /// 0004794 // L-threonine ammonia-lyase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation 205696_s_at NM_005264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005264.1 /DEF=Homo sapiens GDNF family receptor alpha 1 (GFRA1), mRNA. /FEA=mRNA /GEN=GFRA1 /PROD=GDNF family receptor alpha 1 /DB_XREF=gi:4885268 /UG=Hs.105445 GDNF family receptor alpha 1 /FL=gb:U97144.1 gb:AF042080.1 gb:AF038421.1 gb:NM_005264.1 NM_005264 GDNF family receptor alpha 1 GFRA1 2674 NM_001145453 /// NM_005264 /// NM_145793 /// XM_005269696 0001822 // kidney development // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0016167 // glial cell-derived neurotrophic factor receptor activity // traceable author statement 205697_at NM_006998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006998.1 /DEF=Homo sapiens secretagogin (SECRET), mRNA. /FEA=mRNA /GEN=SECRET /PROD=secretagogin /DB_XREF=gi:11321620 /UG=Hs.116428 secretagogin /FL=gb:NM_006998.1 gb:BC000336.1 gb:BC003036.1 gb:Y16752.1 NM_006998 secretagogin, EF-hand calcium binding protein SCGN 10590 NM_006998 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205698_s_at NM_002758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002758.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 6 (MAP2K6), mRNA. /FEA=mRNA /GEN=MAP2K6 /PROD=mitogen-activated protein kinase kinase 6 /DB_XREF=gi:10835026 /UG=Hs.118825 mitogen-activated protein kinase kinase 6 /FL=gb:NM_002758.1 gb:U39656.1 gb:U39657.1 gb:U39065.1 gb:U49732.1 gb:D87905.1 NM_002758 mitogen-activated protein kinase kinase 6 MAP2K6 5608 NM_002758 /// NM_031988 /// XM_005257515 /// XM_005257516 /// XM_005257517 /// XM_006721975 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 205699_at U39657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39657.1 /DEF=Human MAP kinase kinase 6 (MKK6) mRNA, complete cds. /FEA=mRNA /GEN=MKK6 /PROD=MAP kinase kinase 6 /DB_XREF=gi:1203817 /UG=Hs.118825 mitogen-activated protein kinase kinase 6 /FL=gb:NM_002758.1 gb:U39656.1 gb:U39657.1 gb:U39065.1 gb:U49732.1 gb:D87905.1 U39657 mitogen-activated protein kinase kinase 6 MAP2K6 5608 NM_002758 /// NM_031988 /// XM_005257515 /// XM_005257516 /// XM_005257517 /// XM_006721975 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 205700_at NM_003725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003725.1 /DEF=Homo sapiens oxidative 3 alpha hydroxysteroid dehydrogenase; retinol dehydrogenase; 3-hydroxysteroid epimerase (RODH), mRNA. /FEA=mRNA /GEN=RODH /PROD=oxidative 3 alpha hydroxysteroid dehydrogenase;retinol dehydrogenase; 3-hydroxysteroid epimerase /DB_XREF=gi:4506572 /UG=Hs.11958 oxidative 3 alpha hydroxysteroid dehydrogenase; retinol dehydrogenase; 3-hydroxysteroid epimerase /FL=gb:AF016509.1 gb:U89281.1 gb:NM_003725.1 gb:AF223225.1 NM_003725 hydroxysteroid (17-beta) dehydrogenase 6 HSD17B6 8630 NM_003725 /// XM_005269207 /// XM_005269208 /// XM_005269209 /// XM_006719672 /// XR_245961 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // non-traceable author statement /// 0006710 // androgen catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation 205701_at NM_006390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006390.1 /DEF=Homo sapiens RAN binding protein 8 (RANBP8), mRNA. /FEA=mRNA /GEN=RANBP8 /PROD=RAN binding protein 8 /DB_XREF=gi:5453999 /UG=Hs.119687 RAN binding protein 8 /FL=gb:U77494.1 gb:NM_006390.1 NM_006390 importin 8 IPO8 10526 NM_001190995 /// NM_006390 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation 205702_at NM_006608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006608.1 /DEF=Homo sapiens putative homeodomain transcription factor (PHTF1), mRNA. /FEA=mRNA /GEN=PHTF1 /PROD=putative homeodomain transcription factor /DB_XREF=gi:5729975 /UG=Hs.123637 putative homeodomain transcription factor /FL=gb:NM_006608.1 NM_006608 putative homeodomain transcription factor 1 PHTF1 10745 NM_006608 /// XM_005270383 /// XM_005270384 /// XM_005270385 /// XM_005270387 /// XM_006710296 /// XM_006710297 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 205703_at AF112972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF112972.1 /DEF=Homo sapiens TJ6 mRNA, complete cds. /FEA=mRNA /PROD=TJ6 /DB_XREF=gi:4151943 /UG=Hs.12627 TJ6 protein /FL=gb:AF112972.1 gb:NM_012463.1 AF112972 205704_s_at NM_012463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012463.1 /DEF=Homo sapiens TJ6 protein (TJ6), mRNA. /FEA=mRNA /GEN=TJ6 /PROD=TJ6 protein /DB_XREF=gi:6912717 /UG=Hs.12627 TJ6 protein /FL=gb:AF112972.1 gb:NM_012463.1 NM_012463 ATPase, H+ transporting, lysosomal V0 subunit a2 ATP6V0A2 23545 NM_012463 /// XM_005253563 /// XM_006719317 /// XM_006719318 /// XR_429088 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 205705_at AL137351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137351.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E0825 (from clone DKFZp434E0825); partial cds. /FEA=mRNA /GEN=DKFZp434E0825 /PROD=hypothetical protein /DB_XREF=gi:6807865 /UG=Hs.129218 KIAA1074 protein /FL=gb:AB028997.1 gb:NM_014915.1 AL137351 ankyrin repeat domain 26 ANKRD26 22852 NM_001256053 /// NM_014915 /// XM_006717423 /// XM_006717424 /// XM_006717425 /// XM_006717426 /// XM_006717427 /// XM_006717428 /// XM_006717429 /// XM_006717430 /// XM_006717431 /// XM_006717432 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205706_s_at NM_014915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014915.1 /DEF=Homo sapiens KIAA1074 protein (KIAA1074), mRNA. /FEA=mRNA /GEN=KIAA1074 /PROD=KIAA1074 protein /DB_XREF=gi:7662473 /UG=Hs.129218 KIAA1074 protein /FL=gb:AB028997.1 gb:NM_014915.1 NM_014915 ankyrin repeat domain 26 ANKRD26 22852 NM_001256053 /// NM_014915 /// XM_006717423 /// XM_006717424 /// XM_006717425 /// XM_006717426 /// XM_006717427 /// XM_006717428 /// XM_006717429 /// XM_006717430 /// XM_006717431 /// XM_006717432 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205707_at NM_014339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014339.1 /DEF=Homo sapiens interleukin 17 receptor (IL17R), mRNA. /FEA=mRNA /GEN=IL17R /PROD=interleukin 17 receptor /DB_XREF=gi:7657229 /UG=Hs.129751 interleukin 17 receptor /FL=gb:U58917.1 gb:NM_014339.1 NM_014339 interleukin 17 receptor A IL17RA 23765 NM_001289905 /// NM_014339 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0072537 // fibroblast activation // inferred from direct assay /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030368 // interleukin-17 receptor activity // non-traceable author statement 205708_s_at AI051254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI051254 /FEA=EST /DB_XREF=gi:3306788 /DB_XREF=est:oy49e07.x1 /CLONE=IMAGE:1669188 /UG=Hs.133151 transient receptor potential channel 7 /FL=gb:AB001535.1 gb:NM_003307.1 AI051254 transient receptor potential cation channel, subfamily M, member 2 TRPM2 7226 NM_001001188 /// NM_003307 /// NR_038257 /// XM_005261171 /// XM_006724049 /// XM_006724050 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0006828 // manganese ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047631 // ADP-ribose diphosphatase activity // inferred from electronic annotation 205709_s_at NM_001263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001263.1 /DEF=Homo sapiens CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS1), mRNA. /FEA=mRNA /GEN=CDS1 /PROD=CDP-diacylglycerol synthase (phosphatidatecytidylyltransferase) 1 /DB_XREF=gi:4502756 /UG=Hs.152981 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 /FL=gb:U65887.1 gb:NM_001263.1 NM_001263 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 CDS1 1040 NM_001263 /// XM_005262687 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006657 // CDP-choline pathway // non-traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007602 // phototransduction // non-traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from direct assay /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004142 // diacylglycerol cholinephosphotransferase activity // non-traceable author statement /// 0004605 // phosphatidate cytidylyltransferase activity // inferred from direct assay /// 0004605 // phosphatidate cytidylyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 205710_at NM_004525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004525.1 /DEF=Homo sapiens low density lipoprotein-related protein 2 (LRP2), mRNA. /FEA=mRNA /GEN=LRP2 /PROD=low density lipoprotein-related protein 2 /DB_XREF=gi:6806918 /UG=Hs.153595 low density lipoprotein-related protein 2 /FL=gb:U33837.1 gb:NM_004525.1 NM_004525 low density lipoprotein receptor-related protein 2 LRP2 4036 NM_004525 /// XM_006712526 /// XM_006712527 /// XM_006712528 0001523 // retinoid metabolic process // traceable author statement /// 0006486 // protein glycosylation // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0005903 // brush border // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205711_x_at NM_005174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005174.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (ATP5C1), mRNA. /FEA=mRNA /GEN=ATP5C1 /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, gamma polypeptide 1 /DB_XREF=gi:4885078 /UG=Hs.155433 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 /FL=gb:D16563.1 gb:NM_005174.1 NM_005174 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 ATP5C1 509 NM_001001973 /// NM_005174 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred by curator /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 205712_at NM_002839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002839.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), mRNA. /FEA=mRNA /GEN=PTPRD /PROD=protein tyrosine phosphatase, receptor type, D /DB_XREF=gi:4506308 /UG=Hs.158112 protein tyrosine phosphatase, receptor type, D /FL=gb:NM_002839.1 gb:L38929.1 NM_002839 protein tyrosine phosphatase, receptor type, D PTPRD 5789 NM_001040712 /// NM_001171025 /// NM_002839 /// NM_130391 /// NM_130392 /// NM_130393 /// XM_006716813 /// XM_006716814 /// XM_006716815 /// XM_006716816 /// XM_006716817 /// XM_006716818 /// XM_006716819 /// XM_006716820 /// XM_006716821 /// XM_006716822 /// XM_006716823 /// XM_006716824 /// XM_006716825 /// XM_006716826 /// XM_006716827 /// XM_006716828 /// XM_006716829 /// XM_006716830 /// XM_006716831 /// XM_006716832 /// XM_006716833 /// XM_006716834 /// XM_006716835 /// XM_006716836 /// XM_006716837 /// XM_006716838 /// XM_006716839 0006470 // protein dephosphorylation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // non-traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 205713_s_at NM_000095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000095.1 /DEF=Homo sapiens cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) (COMP), mRNA. /FEA=mRNA /GEN=COMP /PROD=cartilage oligomeric matrix protein presursor /DB_XREF=gi:4557482 /UG=Hs.1584 cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) /FL=gb:NM_000095.1 gb:L32137.1 NM_000095 cartilage oligomeric matrix protein COMP 1311 NM_000095 0001501 // skeletal system development // traceable author statement /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0060173 // limb development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay 205714_s_at NM_015896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015896.1 /DEF=Homo sapiens BLu protein (BLu), mRNA. /FEA=mRNA /GEN=BLu /PROD=BLu protein /DB_XREF=gi:7705297 /UG=Hs.167380 BLu protein /FL=gb:U70824.1 gb:NM_015896.1 NM_015896 zinc finger, MYND-type containing 10 ZMYND10 51364 NM_015896 /// XM_005265216 0036158 // outer dynein arm assembly // inferred from mutant phenotype /// 0036159 // inner dynein arm assembly // inferred from mutant phenotype /// 0044458 // motile cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205715_at NM_004334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004334.1 /DEF=Homo sapiens bone marrow stromal cell antigen 1 (BST1), mRNA. /FEA=mRNA /GEN=BST1 /PROD=bone marrow stromal cell antigen 1 precursor /DB_XREF=gi:4757873 /UG=Hs.169998 bone marrow stromal cell antigen 1 /FL=gb:NM_004334.1 gb:D21878.1 NM_004334 bone marrow stromal cell antigen 1 BST1 683 NM_004334 /// XM_005248184 /// XM_005248185 /// XM_005248186 0006959 // humoral immune response // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003953 // NAD+ nucleosidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050135 // NAD(P)+ nucleosidase activity // inferred from electronic annotation 205716_at NM_018843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018843.1 /DEF=Homo sapiens mitochondrial carrier family protein (LOC55972), mRNA. /FEA=mRNA /GEN=LOC55972 /PROD=mitochondrial carrier family protein /DB_XREF=gi:10047121 /UG=Hs.172294 mitochondrial carrier family protein /FL=gb:NM_018843.1 gb:AF125531.1 NM_018843 solute carrier family 25, member 40 SLC25A40 55972 NM_018843 /// XM_005250496 /// XM_005250497 /// XM_006716050 /// XR_242257 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 205717_x_at NM_002588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002588.1 /DEF=Homo sapiens protocadherin gamma subfamily C, 3 (PCDHGC3), mRNA. /FEA=mRNA /GEN=PCDHGC3 /PROD=protocadherin gamma subfamily C, 3 /DB_XREF=gi:4505632 /UG=Hs.173310 protocadherin gamma subfamily C, 3 /FL=gb:L11373.1 gb:NM_002588.1 gb:AF152337.1 NM_002588 protocadherin gamma subfamily A, 1 /// protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 2 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 4 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily A, 7 /// protocadherin gamma subfamily A, 8 /// protocadherin gamma subfamily A, 9 /// protocadherin gamma subfamily B, 1 /// protocadherin gamma subfamily B, 2 /// protocadherin gamma subfamily B, 3 /// protocadherin gamma subfamily B, 4 /// protocadherin gamma subfamily B, 5 /// protocadherin gamma subfamily B, 6 /// protocadherin gamma subfamily B, 7 /// protocadherin gamma subfamily C, 3 /// protocadherin gamma subfamily C, 4 /// protocadherin gamma subfamily C, 5 PCDHGA1 /// PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA2 /// PCDHGA3 /// PCDHGA4 /// PCDHGA5 /// PCDHGA6 /// PCDHGA7 /// PCDHGA8 /// PCDHGA9 /// PCDHGB1 /// PCDHGB2 /// PCDHGB3 /// PCDHGB4 /// PCDHGB5 /// PCDHGB6 /// PCDHGB7 /// PCDHGC3 /// PCDHGC4 /// PCDHGC5 5098 /// 8641 /// 9708 /// 26025 /// 56097 /// 56098 /// 56099 /// 56100 /// 56101 /// 56102 /// 56103 /// 56104 /// 56105 /// 56106 /// 56107 /// 56108 /// 56109 /// 56110 /// 56111 /// 56112 /// 56113 /// 56114 NM_002588 /// NM_003735 /// NM_003736 /// NM_014004 /// NM_018912 /// NM_018913 /// NM_018914 /// NM_018915 /// NM_018916 /// NM_018917 /// NM_018918 /// NM_018919 /// NM_018920 /// NM_018921 /// NM_018922 /// NM_018923 /// NM_018924 /// NM_018925 /// NM_018926 /// NM_018927 /// NM_018928 /// NM_018929 /// NM_031993 /// NM_032009 /// NM_032011 /// NM_032053 /// NM_032054 /// NM_032086 /// NM_032087 /// NM_032088 /// NM_032089 /// NM_032090 /// NM_032091 /// NM_032092 /// NM_032094 /// NM_032095 /// NM_032096 /// NM_032097 /// NM_032098 /// NM_032099 /// NM_032100 /// NM_032101 /// NM_032402 /// NM_032403 /// NM_032406 /// NM_032407 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205718_at NM_000889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000889.1 /DEF=Homo sapiens integrin, beta 7 (ITGB7), mRNA. /FEA=mRNA /GEN=ITGB7 /PROD=integrin, beta 7 /DB_XREF=gi:4504776 /UG=Hs.1741 integrin, beta 7 /FL=gb:M68892.1 gb:M62880.1 gb:NM_000889.1 NM_000889 integrin, beta 7 ITGB7 3695 NM_000889 /// NR_104181 /// XM_005268851 /// XM_005268852 /// XM_006719376 /// XR_429099 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205719_s_at NM_000277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000277.1 /DEF=Homo sapiens phenylalanine hydroxylase (PAH), mRNA. /FEA=mRNA /GEN=PAH /PROD=phenylalanine hydroxylase /DB_XREF=gi:4557818 /UG=Hs.1870 phenylalanine hydroxylase /FL=gb:U49897.1 gb:NM_000277.1 NM_000277 uncharacterized LOC101929036 /// phenylalanine hydroxylase LOC101929036 /// PAH 5053 /// 101929036 NM_000277 /// XR_246028 /// XR_253108 /// XR_424391 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // non-traceable author statement /// 0042423 // catecholamine biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004505 // phenylalanine 4-monooxygenase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016714 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205720_at NM_000939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000939.1 /DEF=Homo sapiens proopiomelanocortin (adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin) (POMC), mRNA. /FEA=mRNA /GEN=POMC /PROD=proopiomelanocortin (adrenocorticotropinbeta-lipotropin alpha-melanocyte stimulating hormonebeta-melanocyte stimulating hormone beta-endorphin) /DB_XREF=gi:4505948 /UG=Hs.1897 proopiomelanocortin (adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin) /FL=gb:NM_000939.1 NM_000939 proopiomelanocortin POMC 5443 NM_000939 /// NM_001035256 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0016486 // peptide hormone processing // traceable author statement /// 0032098 // regulation of appetite // inferred from mutant phenotype /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0033059 // cellular pigmentation // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0034774 // secretory granule lumen // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005179 // hormone activity // inferred from mutant phenotype /// 0005179 // hormone activity // inferred from sequence or structural similarity /// 0031781 // type 3 melanocortin receptor binding // inferred from physical interaction /// 0031782 // type 4 melanocortin receptor binding // inferred from physical interaction /// 0070996 // type 1 melanocortin receptor binding // inferred from direct assay /// 0070996 // type 1 melanocortin receptor binding // inferred from physical interaction 205721_at U97145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U97145.1 /DEF=Homo sapiens RET ligand 2 (RETL2) mRNA, complete cds. /FEA=mRNA /GEN=RETL2 /PROD=RET ligand 2 /DB_XREF=gi:2282027 /UG=Hs.19317 GDNF family receptor alpha 2 /FL=gb:AF002700.1 gb:U93703.1 gb:U97145.1 gb:NM_001495.1 U97145 GDNF family receptor alpha 2 GFRA2 2675 NM_001165038 /// NM_001165039 /// NM_001495 /// XM_005273472 /// XM_005273473 /// XM_005273474 /// XM_005273475 /// XM_006716326 /// XM_006716327 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0016167 // glial cell-derived neurotrophic factor receptor activity // inferred from electronic annotation 205722_s_at NM_001495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001495.1 /DEF=Homo sapiens GDNF family receptor alpha 2 (GFRA2), mRNA. /FEA=mRNA /GEN=GFRA2 /PROD=GDNF family receptor alpha 2 /DB_XREF=gi:4503982 /UG=Hs.19317 GDNF family receptor alpha 2 /FL=gb:AF002700.1 gb:U93703.1 gb:U97145.1 gb:NM_001495.1 NM_001495 GDNF family receptor alpha 2 GFRA2 2675 NM_001165038 /// NM_001165039 /// NM_001495 /// XM_005273472 /// XM_005273473 /// XM_005273474 /// XM_005273475 /// XM_006716326 /// XM_006716327 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0016167 // glial cell-derived neurotrophic factor receptor activity // inferred from electronic annotation 205723_at NM_001842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001842.1 /DEF=Homo sapiens ciliary neurotrophic factor receptor (CNTFR), mRNA. /FEA=mRNA /GEN=CNTFR /PROD=ciliary neurotrophic factor receptor /DB_XREF=gi:4502930 /UG=Hs.194774 ciliary neurotrophic factor receptor /FL=gb:M73238.1 gb:NM_001842.1 NM_001842 ciliary neurotrophic factor receptor CNTFR 1271 NM_001207011 /// NM_001842 /// NM_147164 /// XM_005251362 /// XM_005251363 /// XM_006716720 0001967 // suckling behavior // inferred from electronic annotation /// 0003360 // brainstem development // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0060538 // skeletal muscle organ development // inferred from electronic annotation /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0097059 // CNTFR-CLCF1 complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from physical interaction 205724_at NM_000299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000299.1 /DEF=Homo sapiens plakophilin 1 (ectodermal dysplasiaskin fragility syndrome) (PKP1), mRNA. /FEA=mRNA /GEN=PKP1 /PROD=plakophilin 1 /DB_XREF=gi:4505840 /UG=Hs.198382 plakophilin 1 (ectodermal dysplasiaskin fragility syndrome) /FL=gb:NM_000299.1 NM_000299 plakophilin 1 PKP1 5317 NM_000299 /// NM_001005337 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005882 // intermediate filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from direct assay /// 0019215 // intermediate filament binding // non-traceable author statement /// 0030280 // structural constituent of epidermis // non-traceable author statement 205725_at NM_003357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003357.1 /DEF=Homo sapiens uteroglobin (UGB), mRNA. /FEA=mRNA /GEN=UGB /PROD=uteroglobin /DB_XREF=gi:4507808 /UG=Hs.2240 uteroglobin /FL=gb:BC004481.1 gb:NM_003357.1 gb:U01101.1 NM_003357 secretoglobin, family 1A, member 1 (uteroglobin) SCGB1A1 7356 NM_003357 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007565 // female pregnancy // non-traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010193 // response to ozone // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032696 // negative regulation of interleukin-13 production // inferred from electronic annotation /// 0032713 // negative regulation of interleukin-4 production // inferred from electronic annotation /// 0032714 // negative regulation of interleukin-5 production // inferred from electronic annotation /// 0034021 // response to silicon dioxide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019834 // phospholipase A2 inhibitor activity // inferred from electronic annotation 205726_at NM_006729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006729.1 /DEF=Homo sapiens diaphanous (Drosophila, homolog) 2 (DIAPH2), transcript variant 156, mRNA. /FEA=mRNA /GEN=DIAPH2 /PROD=diaphanous 2 isoform 156 /DB_XREF=gi:5803002 /UG=Hs.226483 diaphanous (Drosophila, homolog) 2 /FL=gb:NM_006729.1 NM_006729 diaphanous-related formin 2 DIAPH2 1730 NM_006729 /// NM_007309 0000910 // cytokinesis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 205727_at NM_007110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007110.1 /DEF=Homo sapiens telomerase-associated protein 1 (TEP1), mRNA. /FEA=mRNA /GEN=TEP1 /PROD=telomerase-associated protein 1 /DB_XREF=gi:6005893 /UG=Hs.232070 telomerase-associated protein 1 /FL=gb:U86136.1 gb:NM_007110.1 NM_007110 telomerase-associated protein 1 TEP1 7011 NM_007110 /// XM_005268027 /// XR_245720 /// XR_429328 0000722 // telomere maintenance via recombination // inferred from direct assay /// 0006278 // RNA-dependent DNA replication // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0030529 // ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 205728_at AL022718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022718 /DEF=Human DNA sequence from clone 1052M9 on chromosome Xq25. Contains the SH2D1A gene for SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome) (DSHP), part of a 60S Acidic Ribosomal protein 1 (RPLP1) LIKE gene and part of a mouse DOC... /FEA=mRNA_3 /DB_XREF=gi:3763969 /UG=Hs.23796 odz (odd Ozten-m, Drosophila) homolog 1 /FL=gb:AF100772.1 gb:NM_014253.1 AL022718 teneurin transmembrane protein 1 TENM1 10178 NM_001163278 /// NM_001163279 /// NM_014253 /// XM_006724725 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 205729_at NM_003999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003999.1 /DEF=Homo sapiens oncostatin M receptor (OSMR), mRNA. /FEA=mRNA /GEN=OSMR /PROD=oncostatin M receptor /DB_XREF=gi:4557039 /UG=Hs.238648 oncostatin M receptor /FL=gb:U60805.1 gb:NM_003999.1 NM_003999 oncostatin M receptor OSMR 9180 NM_001168355 /// NM_003999 /// XM_005248384 /// XM_005248385 /// XM_005248386 /// XM_005248387 /// XM_006714509 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from electronic annotation 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction 205730_s_at NM_014945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014945.1 /DEF=Homo sapiens KIAA0843 protein (KIAA0843), mRNA. /FEA=mRNA /GEN=KIAA0843 /PROD=KIAA0843 protein /DB_XREF=gi:7662329 /UG=Hs.26777 KIAA0843 protein /FL=gb:AB020650.1 gb:NM_014945.1 NM_014945 actin binding LIM protein family, member 3 ABLIM3 22885 NM_014945 /// XM_005268392 /// XM_005268393 /// XM_005268394 /// XM_005268395 /// XM_005268396 /// XM_006714763 /// XM_006714764 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205731_s_at AW027474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027474 /FEA=EST /DB_XREF=gi:5886230 /DB_XREF=est:wt95c08.x1 /CLONE=IMAGE:2515214 /UG=Hs.29131 nuclear receptor coactivator 2 /FL=gb:NM_006540.1 AW027474 nuclear receptor coactivator 2 NCOA2 10499 NM_006540 /// XM_005251128 /// XM_005251129 /// XM_005251130 /// XM_005251131 /// XM_005251132 /// XM_005251133 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from reviewed computational analysis /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 205732_s_at NM_006540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006540.1 /DEF=Homo sapiens nuclear receptor coactivator 2 (NCOA2), mRNA. /FEA=mRNA /GEN=NCOA2 /PROD=nuclear receptor coactivator 2 /DB_XREF=gi:5729857 /UG=Hs.29131 nuclear receptor coactivator 2 /FL=gb:NM_006540.1 NM_006540 nuclear receptor coactivator 2 NCOA2 10499 NM_006540 /// XM_005251128 /// XM_005251129 /// XM_005251130 /// XM_005251131 /// XM_005251132 /// XM_005251133 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from reviewed computational analysis /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 205733_at NM_000057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000057.1 /DEF=Homo sapiens Bloom syndrome (BLM), mRNA. /FEA=mRNA /GEN=BLM /PROD=Bloom syndrome protein /DB_XREF=gi:4557364 /UG=Hs.36820 Bloom syndrome /FL=gb:U39817.1 gb:NM_000057.1 NM_000057 Bloom syndrome, RecQ helicase-like BLM 641 NM_000057 /// NM_001287246 /// NM_001287247 /// NM_001287248 /// XM_006720632 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0000085 // mitotic G2 phase // non-traceable author statement /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0000724 // double-strand break repair via homologous recombination // non-traceable author statement /// 0000729 // DNA double-strand break processing // inferred from direct assay /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0010165 // response to X-ray // inferred from direct assay /// 0031297 // replication fork processing // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // non-traceable author statement /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045910 // negative regulation of DNA recombination // inferred from mutant phenotype /// 0045950 // negative regulation of mitotic recombination // inferred from electronic annotation /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048478 // replication fork protection // non-traceable author statement /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from mutant phenotype /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072711 // cellular response to hydroxyurea // inferred from direct assay /// 0072757 // cellular response to camptothecin // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000800 // lateral element // inferred from direct assay /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000405 // bubble DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0009378 // four-way junction helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation /// 0051880 // G-quadruplex DNA binding // inferred from direct assay 205734_s_at AI990465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI990465 /FEA=EST /DB_XREF=gi:5837346 /DB_XREF=est:wt74h04.x1 /CLONE=IMAGE:2513239 /UG=Hs.38070 lymphoid nuclear protein related to AF4 /FL=gb:U34360.1 gb:NM_002285.1 AI990465 AF4/FMR2 family, member 3 AFF3 3899 NM_001025108 /// NM_002285 /// XM_005263942 /// XM_005263943 /// XM_005263945 /// XM_006712523 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035116 // embryonic hindlimb morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay 205735_s_at NM_002285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002285.1 /DEF=Homo sapiens lymphoid nuclear protein related to AF4 (LAF4), mRNA. /FEA=mRNA /GEN=LAF4 /PROD=lymphoid nuclear protein related to AF4 /DB_XREF=gi:4504938 /UG=Hs.38070 lymphoid nuclear protein related to AF4 /FL=gb:U34360.1 gb:NM_002285.1 NM_002285 AF4/FMR2 family, member 3 AFF3 3899 NM_001025108 /// NM_002285 /// XM_005263942 /// XM_005263943 /// XM_005263945 /// XM_006712523 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035116 // embryonic hindlimb morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay 205736_at NM_000290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000290.1 /DEF=Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2), mRNA. /FEA=mRNA /GEN=PGAM2 /PROD=phosphoglycerate mutase 2 (muscle) /DB_XREF=gi:4505754 /UG=Hs.46039 phosphoglycerate mutase 2 (muscle) /FL=gb:BC001904.1 gb:M18172.1 gb:NM_000290.1 NM_000290 phosphoglycerate mutase 2 (muscle) PGAM2 5224 NM_000290 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from mutant phenotype /// 0006096 // glycolytic process // traceable author statement /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046538 // 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 205737_at NM_004518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004518.1 /DEF=Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), mRNA. /FEA=mRNA /GEN=KCNQ2 /PROD=potassium voltage-gated channel, KQT-likesubfamily, member 2 /DB_XREF=gi:4758627 /UG=Hs.4975 potassium voltage-gated channel, KQT-like subfamily, member 2 /FL=gb:NM_004518.1 NM_004518 potassium voltage-gated channel, KQT-like subfamily, member 2 KCNQ2 3785 NM_004518 /// NM_172106 /// NM_172107 /// NM_172108 /// NM_172109 /// XM_006723787 /// XM_006723788 /// XM_006723789 /// XM_006723790 /// XM_006723791 /// XM_006723792 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction 205738_s_at NM_004102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004102.2 /DEF=Homo sapiens fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (FABP3), mRNA. /FEA=mRNA /GEN=FABP3 /PROD=fatty acid binding protein 3 /DB_XREF=gi:10938020 /UG=Hs.49881 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) /FL=gb:NM_004102.2 NM_004102 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) FABP3 2170 NM_004102 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0044539 // long-chain fatty acid import // inferred from sequence or structural similarity /// 0046320 // regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071073 // positive regulation of phospholipid biosynthetic process // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016528 // sarcoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005324 // long-chain fatty acid transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008289 // lipid binding // traceable author statement /// 0036041 // long-chain fatty acid binding // inferred from direct assay /// 0050543 // icosatetraenoic acid binding // inferred from electronic annotation /// 0070538 // oleic acid binding // inferred from direct assay 205739_x_at NM_016220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016220.1 /DEF=Homo sapiens zinc finger protein (ZFD25) (ZFD25), mRNA. /FEA=mRNA /GEN=ZFD25 /PROD=zinc finger protein (ZFD25) /DB_XREF=gi:7706774 /UG=Hs.50216 zinc finger protein (ZFD25) /FL=gb:AB027251.1 gb:NM_016220.1 NM_016220 zinc finger protein 107 ZNF107 51427 NM_001013746 /// NM_001282359 /// NM_001282360 /// NM_016220 /// NR_104148 /// NR_104149 /// XM_005250401 /// XM_006716022 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205740_s_at NM_024321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024321.1 /DEF=Homo sapiens hypothetical protein MGC10433 (MGC10433), mRNA. /FEA=mRNA /GEN=MGC10433 /PROD=hypothetical protein MGC10433 /DB_XREF=gi:13236562 /UG=Hs.5086 hypothetical protein MGC10433 /FL=gb:BC002868.1 gb:NM_024321.1 NM_024321 RNA binding motif protein 42 RBM42 79171 NM_024321 /// XM_005259257 /// XM_005259258 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205741_s_at NM_001392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001392.1 /DEF=Homo sapiens dystrobrevin, alpha (DTNA), mRNA. /FEA=mRNA /GEN=DTNA /PROD=dystrobrevin, alpha /DB_XREF=gi:4503410 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:BC005300.1 gb:NM_001392.1 NM_001392 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205742_at NM_000363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000363.1 /DEF=Homo sapiens troponin I, cardiac (TNNI3), mRNA. /FEA=mRNA /GEN=TNNI3 /PROD=troponin I, cardiac /DB_XREF=gi:4507622 /UG=Hs.54668 troponin I, cardiac /FL=gb:M64247.1 gb:NM_000363.1 NM_000363 troponin I type 3 (cardiac) TNNI3 7137 NM_000363 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001980 // regulation of systemic arterial blood pressure by ischemic conditions // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0030049 // muscle filament sliding // traceable author statement /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032780 // negative regulation of ATPase activity // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019855 // calcium channel inhibitor activity // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030172 // troponin C binding // inferred from physical interaction /// 0031014 // troponin T binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 205743_at NM_003149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003149.1 /DEF=Homo sapiens src homology three (SH3) and cysteine rich domain (STAC), mRNA. /FEA=mRNA /GEN=STAC /PROD=src homology three (SH3) and cysteine richdomain /DB_XREF=gi:4507246 /UG=Hs.56045 src homology three (SH3) and cysteine rich domain /FL=gb:D86640.1 gb:NM_003149.1 NM_003149 SH3 and cysteine rich domain STAC 6769 NM_001292049 /// NM_003149 /// XM_006713308 /// XM_006713309 0007165 // signal transduction // non-traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205744_at NM_003586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003586.1 /DEF=Homo sapiens double C2-like domains, alpha (DOC2A), mRNA. /FEA=mRNA /GEN=DOC2A /PROD=double C2-like domains, alpha /DB_XREF=gi:4503352 /UG=Hs.57714 double C2-like domains, alpha /FL=gb:NM_003586.1 gb:D31897.1 NM_003586 double C2-like domains, alpha DOC2A 8448 NM_001282062 /// NM_001282063 /// NM_001282068 /// NM_003586 /// NR_104089 /// NR_104090 /// XM_005255635 /// XM_006721097 /// XM_006721098 /// XM_006721099 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation 205745_x_at NM_003183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003183.3 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17), transcript variant 1, mRNA. /FEA=mRNA /GEN=ADAM17 /PROD=a disintegrin and metalloproteinase domain 17,isoform 1 preproprotein /DB_XREF=gi:11497003 /UG=Hs.64311 a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) /FL=gb:NM_003183.3 gb:U86755.1 gb:U69611.1 gb:U92649.1 NM_003183 ADAM metallopeptidase domain 17 ADAM17 6868 NM_003183 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0006508 // proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from mutant phenotype /// 0032722 // positive regulation of chemokine production // inferred from mutant phenotype /// 0033025 // regulation of mast cell apoptotic process // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033627 // cell adhesion mediated by integrin // inferred from direct assay /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from sequence or structural similarity /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from direct assay /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055099 // response to high density lipoprotein particle // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0005112 // Notch binding // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205746_s_at U86755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U86755.1 /DEF=Human TNF-alpha converting enzyme mRNA, complete cds. /FEA=mRNA /PROD=TNF-alpha converting enzyme /DB_XREF=gi:1857672 /UG=Hs.64311 a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) /FL=gb:NM_003183.3 gb:U86755.1 gb:U69611.1 gb:U92649.1 U86755 ADAM metallopeptidase domain 17 ADAM17 6868 NM_003183 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0006508 // proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from mutant phenotype /// 0032722 // positive regulation of chemokine production // inferred from mutant phenotype /// 0033025 // regulation of mast cell apoptotic process // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033627 // cell adhesion mediated by integrin // inferred from direct assay /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from sequence or structural similarity /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from direct assay /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055099 // response to high density lipoprotein particle // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0005112 // Notch binding // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205747_at NM_004352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004352.1 /DEF=Homo sapiens cerebellin 1 precursor (CBLN1), mRNA. /FEA=mRNA /GEN=CBLN1 /PROD=cerebellin 1 precursor /DB_XREF=gi:4757921 /UG=Hs.662 cerebellin 1 precursor /FL=gb:M58583.1 gb:NM_004352.1 NM_004352 cerebellin 1 precursor CBLN1 869 NM_004352 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0009306 // protein secretion // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205748_s_at NM_017876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017876.1 /DEF=Homo sapiens hypothetical protein FLJ20552 (FLJ20552), mRNA. /FEA=mRNA /GEN=FLJ20552 /PROD=hypothetical protein FLJ20552 /DB_XREF=gi:8923521 /UG=Hs.69554 hypothetical protein FLJ20552 /FL=gb:NM_017876.1 NM_017876 ring finger protein 126 RNF126 55658 NM_017876 /// NM_194460 /// XM_005259594 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205749_at NM_000499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000499.2 /DEF=Homo sapiens cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 (CYP1A1), mRNA. /FEA=mRNA /GEN=CYP1A1 /PROD=cytochrome P450, subfamily I (aromaticcompound-inducible), polypeptide 1 /DB_XREF=gi:13325053 /UG=Hs.72912 cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 /FL=gb:NM_000499.2 gb:K03191.1 NM_000499 cytochrome P450, family 1, subfamily A, polypeptide 1 CYP1A1 1543 NM_000499 /// XM_005254185 0001666 // response to hypoxia // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009308 // amine metabolic process // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0009624 // response to nematode // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0009804 // coumarin metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010041 // response to iron(III) ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017143 // insecticide metabolic process // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0019341 // dibenzo-p-dioxin catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032502 // developmental process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // inferred by curator /// 0042493 // response to drug // inferred from electronic annotation /// 0042904 // 9-cis-retinoic acid biosynthetic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0070988 // demethylation // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016679 // oxidoreductase activity, acting on diphenols and related substances as donors // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016711 // flavonoid 3'-monooxygenase activity // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0032451 // demethylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation /// 0070576 // vitamin D 24-hydroxylase activity // inferred from direct assay 205750_at NM_004332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004332.1 /DEF=Homo sapiens biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen) (BPHL), mRNA. /FEA=mRNA /GEN=BPHL /PROD=biphenyl hydrolase-like /DB_XREF=gi:4757861 /UG=Hs.7298 biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen) /FL=gb:NM_004332.1 NM_004332 biphenyl hydrolase-like (serine hydrolase) BPHL 670 NM_004332 /// NR_026648 /// NR_026649 /// NR_026650 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0016045 // detection of bacterium // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004649 // poly(ADP-ribose) glycohydrolase activity // inferred from direct assay /// 0004649 // poly(ADP-ribose) glycohydrolase activity // inferred from electronic annotation /// 0004649 // poly(ADP-ribose) glycohydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205751_at NM_003026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003026.1 /DEF=Homo sapiens SH3-domain GRB2-like 2 (SH3GL2), mRNA. /FEA=mRNA /GEN=SH3GL2 /PROD=SH3-domain GRB2-like 2 /DB_XREF=gi:4506930 /UG=Hs.75149 SH3-domain GRB2-like 2 /FL=gb:AF036268.1 gb:NM_003026.1 NM_003026 SH3-domain GRB2-like 2 SH3GL2 6456 NM_003026 /// XM_005251549 0002090 // regulation of receptor internalization // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 205752_s_at NM_000851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000851.1 /DEF=Homo sapiens glutathione S-transferase M5 (GSTM5), mRNA. /FEA=mRNA /GEN=GSTM5 /PROD=glutathione S-transferase M5 /DB_XREF=gi:4504180 /UG=Hs.75652 glutathione S-transferase M5 /FL=gb:NM_000851.1 gb:L02321.1 NM_000851 glutathione S-transferase mu 5 GSTM5 2949 NM_000851 /// XM_005270784 /// XM_005270785 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205753_at NM_000567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000567.1 /DEF=Homo sapiens C-reactive protein, pentraxin-related (CRP), mRNA. /FEA=mRNA /GEN=CRP /PROD=C-reactive protein, pentraxin-related /DB_XREF=gi:10835134 /UG=Hs.76452 C-reactive protein, pentraxin-related /FL=gb:NM_000567.1 NM_000567 C-reactive protein, pentraxin-related CRP 1401 NM_000567 0001666 // response to hypoxia // inferred from electronic annotation /// 0006953 // acute-phase response // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008228 // opsonization // traceable author statement /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010888 // negative regulation of lipid storage // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0033265 // choline binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046790 // virion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205754_at NM_000506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000506.2 /DEF=Homo sapiens coagulation factor II (thrombin) (F2), mRNA. /FEA=mRNA /GEN=F2 /PROD=coagulation factor II precursor /DB_XREF=gi:5922005 /UG=Hs.76530 coagulation factor II (thrombin) /FL=gb:NM_000506.2 NM_000506 coagulation factor II (thrombin) F2 2147 NM_000506 /// XR_428840 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0042730 // fibrinolysis // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0048712 // negative regulation of astrocyte differentiation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // traceable author statement /// 1900738 // positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070053 // thrombospondin receptor activity // inferred from direct assay 205755_at NM_002217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002217.1 /DEF=Homo sapiens pre-alpha (globulin) inhibitor, H3 polypeptide (ITIH3), mRNA. /FEA=mRNA /GEN=ITIH3 /PROD=pre-alpha (globulin) inhibitor, H3 polypeptide /DB_XREF=gi:10092578 /UG=Hs.76716 pre-alpha (globulin) inhibitor, H3 polypeptide /FL=gb:NM_002217.1 NM_002217 inter-alpha-trypsin inhibitor heavy chain 3 ITIH3 3699 NM_002217 /// XM_005265105 /// XM_006713129 /// XM_006713130 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 205756_s_at NM_000132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000132.2 /DEF=Homo sapiens coagulation factor VIII, procoagulant component (hemophilia A) (F8), transcript variant 1, mRNA. /FEA=mRNA /GEN=F8 /PROD=coagulation factor VIII, procoagulant component,isoform a precursor /DB_XREF=gi:10518504 /UG=Hs.79345 coagulation factor VIII, procoagulant component (hemophilia A) /FL=gb:NM_000132.2 gb:M14113.1 NM_000132 coagulation factor VIII, procoagulant component F8 2157 NM_000132 /// NM_019863 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205757_at NM_001249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001249.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), mRNA. /FEA=mRNA /GEN=ENTPD5 /PROD=ectonucleoside triphosphate diphosphohydrolase5 /DB_XREF=gi:4557426 /UG=Hs.80975 ectonucleoside triphosphate diphosphohydrolase 5 /FL=gb:AF039918.1 gb:NM_001249.1 NM_001249 ectonucleoside triphosphate diphosphohydrolase 5 ENTPD5 957 NM_001249 /// XM_005268221 /// XM_005268222 /// XM_005268224 /// XM_006720324 /// XM_006720325 /// XM_006720326 0006096 // glycolytic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0014066 // regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016049 // cell growth // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from sequence or structural similarity /// 0051084 // 'de novo' posttranslational protein folding // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004382 // guanosine-diphosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from sequence or structural similarity 205758_at AW006735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006735 /FEA=EST /DB_XREF=gi:5855513 /DB_XREF=est:wr28g01.x1 /CLONE=IMAGE:2489040 /UG=Hs.85258 CD8 antigen, alpha polypeptide (p32) /FL=gb:NM_001768.1 AW006735 CD8a molecule CD8A 925 NM_001145873 /// NM_001768 /// NM_171827 /// NR_027353 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0019882 // antigen processing and presentation // non-traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0045065 // cytotoxic T cell differentiation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205759_s_at NM_004605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004605.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 2B, member 1 (SULT2B1), mRNA. /FEA=mRNA /GEN=SULT2B1 /PROD=sulfotransferase family, cytosolic, 2B, member1 /DB_XREF=gi:4759191 /UG=Hs.94581 sulfotransferase family, cytosolic, 2B, member 1 /FL=gb:U92314.1 gb:NM_004605.1 NM_004605 sulfotransferase family, cytosolic, 2B, member 1 SULT2B1 6820 NM_004605 /// NM_177973 /// XM_005259182 0000103 // sulfate assimilation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004027 // alcohol sulfotransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050294 // steroid sulfotransferase activity // inferred from direct assay 205760_s_at NM_016821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016821.1 /DEF=Homo sapiens 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a, mRNA. /FEA=mRNA /GEN=OGG1 /PROD=8-oxoguanine DNA glycosylase, isoform 2a /DB_XREF=gi:8670533 /UG=Hs.96398 8-oxoguanine DNA glycosylase /FL=gb:U88620.1 gb:NM_016821.1 NM_016821 8-oxoguanine DNA glycosylase OGG1 4968 NM_002542 /// NM_016819 /// NM_016820 /// NM_016821 /// NM_016826 /// NM_016827 /// NM_016828 /// NM_016829 /// XM_005265185 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from direct assay /// 0045007 // depurination // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051835 // positive regulation of synapse structural plasticity // inferred from mutant phenotype /// 0060999 // positive regulation of dendritic spine development // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008534 // oxidized purine nucleobase lesion DNA N-glycosylase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation /// 0034039 // 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity // inferred from electronic annotation 205761_s_at AW242981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242981 /FEA=EST /DB_XREF=gi:6576759 /DB_XREF=est:xm91g11.x1 /CLONE=IMAGE:2691620 /UG=Hs.97627 protein similar to E.coli yhdg and R. capsulatus nifR3 /FL=gb:U62767.1 gb:NM_007016.1 AW242981 dihydrouridine synthase 4-like (S. cerevisiae) DUS4L 11062 NM_001270419 /// NM_181581 /// NR_073002 /// NR_073003 /// NR_073004 /// NR_073005 /// XM_005250125 /// XM_006715844 /// XM_006715845 0002943 // tRNA dihydrouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 205762_s_at NM_007016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007016.1 /DEF=Homo sapiens protein similar to E.coli yhdg and R. capsulatus nifR3 (PP35), mRNA. /FEA=mRNA /GEN=PP35 /PROD=protein similar to E.coli yhdg and R. capsulatusnifR3 /DB_XREF=gi:5902025 /UG=Hs.97627 protein similar to E.coli yhdg and R. capsulatus nifR3 /FL=gb:U62767.1 gb:NM_007016.1 NM_007016 dihydrouridine synthase 4-like (S. cerevisiae) DUS4L 11062 NM_001270419 /// NM_181581 /// NR_073002 /// NR_073003 /// NR_073004 /// NR_073005 /// XM_005250125 /// XM_006715844 /// XM_006715845 0002943 // tRNA dihydrouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 205763_s_at NM_006773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006773.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated) (DDX18), mRNA. /FEA=mRNA /GEN=DDX18 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 /DB_XREF=gi:13787205 /UG=Hs.100555 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated) /FL=gb:NM_006773.2 NM_006773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DDX18 8886 NM_006773 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205764_at NM_002932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002932.1 /DEF=Homo sapiens regulator of mitotic spindle assembly 1 (RMSA1), mRNA. /FEA=mRNA /GEN=RMSA1 /PROD=regulator of mitotic spindle assembly 1 /DB_XREF=gi:4506544 /UG=Hs.1010 regulator of mitotic spindle assembly 1 /FL=gb:NM_002932.1 gb:L26953.1 NM_002932 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205765_at NM_000777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000777.1 /DEF=Homo sapiens cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5 (CYP3A5), mRNA. /FEA=mRNA /GEN=CYP3A5 /PROD=cytochrome P450, subfamily IIIA, polypeptide 5 /DB_XREF=gi:4503230 /UG=Hs.104117 cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5 /FL=gb:J04813.1 gb:NM_000777.1 NM_000777 cytochrome P450, family 3, subfamily A, polypeptide 5 CYP3A5 1577 NM_000777 /// NM_001190484 /// NM_001291829 /// NM_001291830 /// NR_033807 /// NR_033808 /// NR_033809 /// NR_033810 /// NR_033811 /// NR_033812 /// XM_006715859 /// XM_006715860 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070989 // oxidative demethylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 205766_at NM_003673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003673.1 /DEF=Homo sapiens titin-cap (telethonin) (TCAP), mRNA. /FEA=mRNA /GEN=TCAP /PROD=titin-cap (telethonin) /DB_XREF=gi:4507434 /UG=Hs.111110 titin-cap (telethonin) /FL=gb:NM_003673.1 NM_003673 titin-cap TCAP 8557 NM_003673 0001756 // somitogenesis // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from expression pattern /// 0003300 // cardiac muscle hypertrophy // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0007512 // adult heart development // inferred from mutant phenotype /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement /// 0030240 // skeletal muscle thin filament assembly // inferred from mutant phenotype /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from mutant phenotype /// 0030916 // otic vesicle formation // inferred from electronic annotation /// 0035994 // response to muscle stretch // traceable author statement /// 0035995 // detection of muscle stretch // inferred from mutant phenotype /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045214 // sarcomere organization // traceable author statement /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype /// 0048769 // sarcomerogenesis // inferred from mutant phenotype /// 0050982 // detection of mechanical stimulus // traceable author statement /// 0055003 // cardiac myofibril assembly // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0030674 // protein binding, bridging // inferred from direct assay /// 0031432 // titin binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0051373 // FATZ binding // inferred from physical interaction /// 0070080 // titin Z domain binding // inferred from physical interaction 205767_at NM_001432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001432.1 /DEF=Homo sapiens epiregulin (EREG), mRNA. /FEA=mRNA /GEN=EREG /PROD=epiregulin precursor /DB_XREF=gi:4557566 /UG=Hs.115263 epiregulin /FL=gb:D30783.1 gb:NM_001432.1 NM_001432 epiregulin EREG 2069 NM_001432 0001525 // angiogenesis // inferred from electronic annotation /// 0001550 // ovarian cumulus expansion // inferred from sequence or structural similarity /// 0001556 // oocyte maturation // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0007143 // female meiotic division // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009299 // mRNA transcription // inferred from direct assay /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042108 // positive regulation of cytokine biosynthetic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from sequence or structural similarity /// 0042700 // luteinizing hormone signaling pathway // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from sequence or structural similarity /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048160 // primary follicle stage // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // traceable author statement /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005154 // epidermal growth factor receptor binding // inferred from sequence or structural similarity /// 0005154 // epidermal growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 205768_s_at NM_003645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003645.1 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, very long-chain 1 (FACVL1), mRNA. /FEA=mRNA /GEN=FACVL1 /PROD=very long-chain fatty-acid-Coenzyme A ligase 1 /DB_XREF=gi:4503652 /UG=Hs.11729 fatty-acid-Coenzyme A ligase, very long-chain 1 /FL=gb:D88308.1 gb:AF096290.1 gb:NM_003645.1 NM_003645 solute carrier family 27 (fatty acid transporter), member 2 SLC27A2 11001 NM_001159629 /// NM_003645 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001561 // fatty acid alpha-oxidation // inferred from direct assay /// 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0042760 // very long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0097089 // methyl-branched fatty acid metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015245 // fatty acid transporter activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0050197 // phytanate-CoA ligase activity // inferred from direct assay /// 0070251 // pristanate-CoA ligase activity // inferred from direct assay 205769_at NM_003645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003645.1 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, very long-chain 1 (FACVL1), mRNA. /FEA=mRNA /GEN=FACVL1 /PROD=very long-chain fatty-acid-Coenzyme A ligase 1 /DB_XREF=gi:4503652 /UG=Hs.11729 fatty-acid-Coenzyme A ligase, very long-chain 1 /FL=gb:D88308.1 gb:AF096290.1 gb:NM_003645.1 NM_003645 solute carrier family 27 (fatty acid transporter), member 2 SLC27A2 11001 NM_001159629 /// NM_003645 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001561 // fatty acid alpha-oxidation // inferred from direct assay /// 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0042760 // very long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0097089 // methyl-branched fatty acid metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015245 // fatty acid transporter activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0050197 // phytanate-CoA ligase activity // inferred from direct assay /// 0070251 // pristanate-CoA ligase activity // inferred from direct assay 205770_at NM_000637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000637.1 /DEF=Homo sapiens glutathione reductase (GSR), mRNA. /FEA=mRNA /GEN=GSR /PROD=glutathione reductase /DB_XREF=gi:10835188 /UG=Hs.121524 glutathione reductase /FL=gb:NM_000637.1 gb:AF228704.1 NM_000637 glutathione reductase GSR 2936 NM_000637 /// NM_001195102 /// NM_001195103 /// NM_001195104 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004362 // glutathione-disulfide reductase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 205771_s_at AL137063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137063 /DEF=Human DNA sequence from clone RP1-104L14 on chromosome 6 Contains part of the AKAP7 (A kinase (PRKA) anchor protein 7) gene, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:9581554 /UG=Hs.12835 A kinase (PRKA) anchor protein 7 /FL=gb:AF047715.1 gb:NM_004842.1 AL137063 A kinase (PRKA) anchor protein 7 AKAP7 9465 NM_004842 /// NM_016377 /// NM_138633 /// XM_005267228 /// XM_005267229 /// XM_006715614 /// XR_427979 0001508 // action potential // inferred by curator /// 0006811 // ion transport // traceable author statement /// 0008104 // protein localization // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902261 // positive regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070382 // exocytic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay /// 0051018 // protein kinase A binding // traceable author statement 205772_s_at NM_004842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004842.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 7 (AKAP7), mRNA. /FEA=mRNA /GEN=AKAP7 /PROD=A kinase (PRKA) anchor protein 7 /DB_XREF=gi:4757737 /UG=Hs.12835 A kinase (PRKA) anchor protein 7 /FL=gb:AF047715.1 gb:NM_004842.1 NM_004842 0001508 // action potential // inferred by curator /// 0006811 // ion transport // traceable author statement /// 0008104 // protein localization // inferred by curator /// 0035556 // intracellular signal transduction // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902261 // positive regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation 0051018 // protein kinase A binding // inferred from direct assay /// 0051018 // protein kinase A binding // traceable author statement 205773_at NM_014912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014912.1 /DEF=Homo sapiens KIAA0940 protein (KIAA0940), mRNA. /FEA=mRNA /GEN=KIAA0940 /PROD=KIAA0940 protein /DB_XREF=gi:7662391 /UG=Hs.131945 KIAA0940 protein /FL=gb:AB023157.1 gb:NM_014912.1 NM_014912 cytoplasmic polyadenylation element binding protein 3 CPEB3 22849 NM_001178137 /// NM_014912 /// XM_005269630 /// XM_006717714 /// XM_006717715 /// XM_006717716 /// XM_006717717 /// XM_006717718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006412 // translation // inferred from direct assay /// 0006412 // translation // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0060999 // positive regulation of dendritic spine development // inferred from sequence or structural similarity /// 0061158 // 3'-UTR-mediated mRNA destabilization // inferred from direct assay /// 0071230 // cellular response to amino acid stimulus // inferred from direct assay /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay /// 1900248 // negative regulation of cytoplasmic translational elongation // inferred from sequence or structural similarity /// 1900365 // positive regulation of mRNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030014 // CCR4-NOT complex // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0008135 // translation factor activity, nucleic acid binding // inferred from sequence or structural similarity /// 0035613 // RNA stem-loop binding // inferred from sequence or structural similarity /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 205774_at NM_000505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000505.2 /DEF=Homo sapiens coagulation factor XII (Hageman factor) (F12), mRNA. /FEA=mRNA /GEN=F12 /PROD=coagulation factor XII precursor /DB_XREF=gi:9961354 /UG=Hs.1321 coagulation factor XII (Hageman factor) /FL=gb:NM_000505.2 NM_000505 coagulation factor XII (Hageman factor) F12 2161 NM_000505 0002353 // plasma kallikrein-kinin cascade // inferred from direct assay /// 0002542 // Factor XII activation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // inferred by curator /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010756 // positive regulation of plasminogen activation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016540 // protein autoprocessing // inferred from direct assay /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0031638 // zymogen activation // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051788 // response to misfolded protein // inferred from direct assay /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051787 // misfolded protein binding // inferred by curator /// 0070009 // serine-type aminopeptidase activity // inferred from electronic annotation 205775_at NM_012135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012135.1 /DEF=Homo sapiens DNA segment on chromosome 6(unique) 2654 expressed sequence (D6S2654E), mRNA. /FEA=mRNA /GEN=D6S2654E /PROD=DNA segment on chromosome 6(unique) 2654expressed sequence /DB_XREF=gi:6912325 /UG=Hs.140944 DNA segment on chromosome 6(unique) 2654 expressed sequence /FL=gb:BC001261.1 gb:NM_012135.1 NM_012135 family with sequence similarity 50, member B FAM50B 26240 NM_012135 0005634 // nucleus // inferred from electronic annotation 205776_at NM_001461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001461.1 /DEF=Homo sapiens flavin containing monooxygenase 5 (FMO5), mRNA. /FEA=mRNA /GEN=FMO5 /PROD=flavin containing monooxygenase 5 /DB_XREF=gi:4503760 /UG=Hs.14286 flavin containing monooxygenase 5 /FL=gb:NM_001461.1 gb:L37080.1 NM_001461 flavin containing monooxygenase 5 FMO5 2330 NM_001144829 /// NM_001144830 /// NM_001461 /// XM_005272946 /// XM_005272947 /// XM_005272948 /// XM_006711244 /// XM_006711245 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 205777_at NM_001395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001395.1 /DEF=Homo sapiens dual specificity phosphatase 9 (DUSP9), mRNA. /FEA=mRNA /GEN=DUSP9 /PROD=dual specificity phosphatase 9 /DB_XREF=gi:4503420 /UG=Hs.144879 dual specificity phosphatase 9 /FL=gb:NM_001395.1 NM_001395 dual specificity phosphatase 9 DUSP9 1852 NM_001395 /// XM_005274655 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // not recorded /// 0007254 // JNK cascade // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 205778_at NM_005046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005046.1 /DEF=Homo sapiens kallikrein 7 (chymotryptic, stratum corneum) (KLK7), mRNA. /FEA=mRNA /GEN=KLK7 /PROD=kallikrein 7 (chymotryptic, stratum corneum) /DB_XREF=gi:4826949 /UG=Hs.151254 kallikrein 7 (chymotryptic, stratum corneum) /FL=gb:NM_005046.1 gb:L33404.1 NM_005046 kallikrein-related peptidase 7 KLK7 5650 NM_001207053 /// NM_001243126 /// NM_005046 /// NM_139277 0006508 // proteolysis // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0097209 // epidermal lamellar body // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205779_at NM_005854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005854.1 /DEF=Homo sapiens receptor (calcitonin) activity modifying protein 2 (RAMP2), mRNA. /FEA=mRNA /GEN=RAMP2 /PROD=receptor (calcitonin) activity modifying protein2 precursor /DB_XREF=gi:5032020 /UG=Hs.155106 receptor (calcitonin) activity modifying protein 2 /FL=gb:NM_005854.1 NM_005854 receptor (G protein-coupled) activity modifying protein 2 RAMP2 10266 NM_005854 0001525 // angiogenesis // inferred from direct assay /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0015031 // protein transport // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034333 // adherens junction assembly // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from sequence or structural similarity /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // inferred from direct assay /// 0070831 // basement membrane assembly // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay /// 0015026 // coreceptor activity // inferred from sequence or structural similarity 205780_at NM_001197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001197.2 /DEF=Homo sapiens BCL2-interacting killer (apoptosis-inducing) (BIK), mRNA. /FEA=mRNA /GEN=BIK /PROD=BCL2-interacting killer /DB_XREF=gi:7262371 /UG=Hs.155419 BCL2-interacting killer (apoptosis-inducing) /FL=gb:U49730.1 gb:U34584.1 gb:BC001599.1 gb:NM_001197.2 NM_001197 BCL2-interacting killer (apoptosis-inducing) BIK 638 NM_001197 0006915 // apoptotic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051400 // BH domain binding // inferred from electronic annotation 205781_at NM_004913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004913.1 /DEF=Homo sapiens chromosome 16 open reading frame 7 (C16ORF7), mRNA. /FEA=mRNA /GEN=C16ORF7 /PROD=chromosome 16 open reading frame 7 /DB_XREF=gi:4757805 /UG=Hs.164410 chromosome 16 open reading frame 7 /FL=gb:AB018551.1 gb:NM_004913.1 NM_004913 VPS9 domain containing 1 VPS9D1 9605 NM_004913 /// XM_005256329 /// XM_005256330 /// XM_005256331 /// XM_006721350 0015986 // ATP synthesis coupled proton transport // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement 205782_at NM_002009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002009.1 /DEF=Homo sapiens fibroblast growth factor 7 (keratinocyte growth factor) (FGF7), mRNA. /FEA=mRNA /GEN=FGF7 /PROD=fibroblast growth factor 7 (keratinocyte growthfactor) /DB_XREF=gi:4503704 /UG=Hs.164568 fibroblast growth factor 7 (keratinocyte growth factor) /FL=gb:M60828.1 gb:NM_002009.1 NM_002009 fibroblast growth factor 7 FGF7 2252 NM_002009 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0010463 // mesenchymal cell proliferation // inferred from direct assay /// 0010838 // positive regulation of keratinocyte proliferation // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051549 // positive regulation of keratinocyte migration // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0061033 // secretion by lung epithelial cell involved in lung growth // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay 205783_at NM_015596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015596.1 /DEF=Homo sapiens kallikrein 13 (KLK13), mRNA. /FEA=mRNA /GEN=KLK13 /PROD=kallikrein 13 /DB_XREF=gi:11496280 /UG=Hs.165296 kallikrein 13 /FL=gb:NM_015596.1 NM_015596 kallikrein-related peptidase 13 KLK13 26085 NM_015596 0006508 // proteolysis // non-traceable author statement /// 0016485 // protein processing // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030141 // secretory granule // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from direct assay 205784_x_at NM_001670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001670.1 /DEF=Homo sapiens armadillo repeat gene deletes in velocardiofacial syndrome (ARVCF), mRNA. /FEA=mRNA /GEN=ARVCF /PROD=armadillo repeat protein /DB_XREF=gi:4502246 /UG=Hs.171900 armadillo repeat gene deletes in velocardiofacial syndrome /FL=gb:U51269.1 gb:NM_001670.1 NM_001670 armadillo repeat gene deleted in velocardiofacial syndrome ARVCF 421 NM_001670 /// XM_005261242 /// XM_005261243 /// XM_005261244 /// XM_006724243 /// XM_006724244 /// XM_006724245 /// XM_006724246 /// XM_006724247 /// XM_006724248 /// XM_006724249 /// XM_006724250 /// XM_006724251 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205785_at J03925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J03925.1 /DEF=Human Mac-1 gene encoding complement receptor type 3, CD11b, complete cds. /FEA=mRNA /GEN=ITGAM /DB_XREF=gi:187284 /UG=Hs.172631 integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide) /FL=gb:J03925.1 gb:NM_000632.2 J03925 205786_s_at NM_000632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000632.2 /DEF=Homo sapiens integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide) (ITGAM), mRNA. /FEA=mRNA /GEN=ITGAM /PROD=integrin alpha M precursor /DB_XREF=gi:6006013 /UG=Hs.172631 integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide) /FL=gb:J03925.1 gb:NM_000632.2 NM_000632 integrin, alpha M (complement component 3 receptor 3 subunit) ITGAM 3684 NM_000632 /// NM_001145808 /// XM_006721045 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0014005 // microglia development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045123 // cellular extravasation // inferred from electronic annotation /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001846 // opsonin binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205787_x_at AI803216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803216 /FEA=EST /DB_XREF=gi:5368688 /DB_XREF=est:tc15d10.x1 /CLONE=IMAGE:2063923 /UG=Hs.17969 KIAA0663 gene product /FL=gb:AB014563.1 gb:NM_014827.1 AI803216 zinc finger CCCH-type domain-containing-like /// zinc finger CCCH-type containing 11A LOC441155 /// ZC3H11A 9877 /// 441155 NM_001271675 /// NM_014827 /// XM_005245643 /// XM_005245644 /// XM_005245646 /// XM_006711673 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205788_s_at NM_014827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014827.1 /DEF=Homo sapiens KIAA0663 gene product (KIAA0663), mRNA. /FEA=mRNA /GEN=KIAA0663 /PROD=KIAA0663 gene product /DB_XREF=gi:7662231 /UG=Hs.17969 KIAA0663 gene product /FL=gb:AB014563.1 gb:NM_014827.1 NM_014827 zinc finger CCCH-type domain-containing-like /// zinc finger CCCH-type containing 11A LOC441155 /// ZC3H11A 9877 /// 441155 NM_001271675 /// NM_014827 /// XM_005245643 /// XM_005245644 /// XM_005245646 /// XM_006711673 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205789_at NM_001766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001766.1 /DEF=Homo sapiens CD1D antigen, d polypeptide (CD1D), mRNA. /FEA=mRNA /GEN=CD1D /PROD=CD1D antigen, d polypeptide /DB_XREF=gi:4502648 /UG=Hs.1799 CD1D antigen, d polypeptide /FL=gb:NM_001766.1 gb:J04142.1 NM_001766 CD1d molecule CD1D 912 NM_001766 /// XM_005245583 /// XM_006711620 /// XM_006711621 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016045 // detection of bacterium // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0045058 // T cell selection // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045089 // positive regulation of innate immune response // traceable author statement /// 0048006 // antigen processing and presentation, endogenous lipid antigen via MHC class Ib // inferred from direct assay /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred by curator /// 0005515 // protein binding // inferred from electronic annotation /// 0030881 // beta-2-microglobulin binding // traceable author statement /// 0030882 // lipid antigen binding // inferred from direct assay /// 0030883 // endogenous lipid antigen binding // not recorded /// 0030884 // exogenous lipid antigen binding // inferred from direct assay /// 0042393 // histone binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0071723 // lipopeptide binding // not recorded 205790_at NM_003726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003726.1 /DEF=Homo sapiens src kinase-associated phosphoprotein of 55 kDa (SKAP55), mRNA. /FEA=mRNA /GEN=SKAP55 /PROD=src kinase-associated phosphoprotein of 55 kDa /DB_XREF=gi:4506964 /UG=Hs.19126 src kinase-associated phosphoprotein of 55 kDa /FL=gb:NM_003726.1 NM_003726 src kinase associated phosphoprotein 1 SKAP1 8631 NM_001075099 /// NM_003726 /// XM_005257755 /// XM_005257756 /// XM_005257757 0002376 // immune system process // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003823 // antigen binding // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from direct assay 205791_x_at NM_006300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006300.1 /DEF=Homo sapiens zinc finger protein 230 (ZNF230), mRNA. /FEA=mRNA /GEN=ZNF230 /PROD=zinc finger protein 230 /DB_XREF=gi:5454181 /UG=Hs.193583 zinc finger protein 230 /FL=gb:U95044.1 gb:NM_006300.1 NM_006300 zinc finger protein 230 ZNF230 7773 NM_006300 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205792_at NM_003881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003881.1 /DEF=Homo sapiens WNT1 inducible signaling pathway protein 2 (WISP2), mRNA. /FEA=mRNA /GEN=WISP2 /PROD=WNT1 inducible signaling pathway protein 2 /DB_XREF=gi:4507922 /UG=Hs.194679 WNT1 inducible signaling pathway protein 2 /FL=gb:AF074604.1 gb:AF083500.1 gb:AF100780.1 gb:NM_003881.1 NM_003881 WNT1 inducible signaling pathway protein 2 WISP2 8839 NM_003881 /// XM_005260603 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation 205793_x_at NM_003985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003985.1 /DEF=Homo sapiens tyrosine kinase, non-receptor, 1 (TNK1), mRNA. /FEA=mRNA /GEN=TNK1 /PROD=tyrosine kinase, non-receptor, 1 /DB_XREF=gi:4507610 /UG=Hs.203420 tyrosine kinase, non-receptor, 1 /FL=gb:U43408.1 gb:NM_003985.1 NM_003985 tyrosine kinase, non-receptor, 1 TNK1 8711 NM_001251902 /// NM_003985 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205794_s_at NM_002515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002515.1 /DEF=Homo sapiens neuro-oncological ventral antigen 1 (NOVA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=NOVA1 /PROD=neuro-oncological ventral antigen 1, isoform 1 /DB_XREF=gi:4505424 /UG=Hs.214 neuro-oncological ventral antigen 1 /FL=gb:U04840.1 gb:NM_002515.1 NM_002515 neuro-oncological ventral antigen 1 NOVA1 4857 NM_002515 /// NM_006489 /// NM_006491 /// XM_005267707 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // traceable author statement /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205795_at NM_004796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004796.1 /DEF=Homo sapiens neurexin 3 (NRXN3), mRNA. /FEA=mRNA /GEN=NRXN3 /PROD=neurexin 3 /DB_XREF=gi:4758827 /UG=Hs.22269 neurexin 3 /FL=gb:AB018286.1 gb:NM_004796.1 NM_004796 neurexin 3 NRXN3 9369 NM_001105250 /// NM_001272020 /// NM_004796 /// NM_138970 /// NR_073546 /// NR_073547 /// XM_005268218 /// XM_006720322 /// XM_006720323 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007612 // learning // inferred from genetic interaction /// 0030534 // adult behavior // inferred from genetic interaction /// 0035176 // social behavior // inferred from genetic interaction /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0071625 // vocalization behavior // inferred from genetic interaction /// 0090129 // positive regulation of synapse maturation // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // traceable author statement /// 0097109 // neuroligin family protein binding // traceable author statement 205796_at NM_018393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018393.1 /DEF=Homo sapiens hypothetical protein FLJ11336 (FLJ11336), mRNA. /FEA=mRNA /GEN=FLJ11336 /PROD=hypothetical protein FLJ11336 /DB_XREF=gi:8922998 /UG=Hs.22383 hypothetical protein FLJ11336 /FL=gb:NM_018393.1 NM_018393 t-complex 11, testis-specific-like 1 TCP11L1 55346 NM_001145541 /// NM_018393 /// XM_006718256 /// XM_006718257 /// XR_428846 0005874 // microtubule // inferred from direct assay 205797_s_at NM_018393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018393.1 /DEF=Homo sapiens hypothetical protein FLJ11336 (FLJ11336), mRNA. /FEA=mRNA /GEN=FLJ11336 /PROD=hypothetical protein FLJ11336 /DB_XREF=gi:8922998 /UG=Hs.22383 hypothetical protein FLJ11336 /FL=gb:NM_018393.1 NM_018393 t-complex 11, testis-specific-like 1 TCP11L1 55346 NM_001145541 /// NM_018393 /// XM_006718256 /// XM_006718257 /// XR_428846 0005874 // microtubule // inferred from direct assay 205798_at NM_002185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002185.1 /DEF=Homo sapiens interleukin 7 receptor (IL7R), mRNA. /FEA=mRNA /GEN=IL7R /PROD=interleukin 7 receptor /DB_XREF=gi:4504678 /UG=Hs.237868 interleukin 7 receptor /FL=gb:M29696.1 gb:NM_002185.1 NM_002185 interleukin 7 receptor IL7R 3575 NM_002185 /// NR_120485 /// XM_005248299 /// XM_005248300 0000018 // regulation of DNA recombination // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002377 // immunoglobulin production // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0038111 // interleukin-7-mediated signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004917 // interleukin-7 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205799_s_at M95548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M95548.1 /DEF=Homo sapiens amino acid transport protein mRNA, complete cds. /FEA=mRNA /PROD=amino acid transport protein /DB_XREF=gi:306441 /UG=Hs.239106 solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 /FL=gb:AB033549.1 gb:D82326.1 gb:M95548.1 gb:L11696.1 gb:NM_000341.1 M95548 solute carrier family 3 (amino acid transporter heavy chain), member 1 SLC3A1 6519 NM_000341 0003333 // amino acid transmembrane transport // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015802 // basic amino acid transport // traceable author statement /// 0015811 // L-cystine transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // traceable author statement /// 0015174 // basic amino acid transmembrane transporter activity // traceable author statement /// 0015184 // L-cystine transmembrane transporter activity // traceable author statement /// 0043169 // cation binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205800_at NM_000341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000341.1 /DEF=Homo sapiens solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (SLC3A1), mRNA. /FEA=mRNA /GEN=SLC3A1 /PROD=solute carrier family 3 (cystine, dibasic andneutral amino acid transporters, activator of cystine,dibasic and neutral amino acid transport), member 1 /DB_XREF=gi:4507018 /UG=Hs.239106 solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 /FL=gb:AB033549.1 gb:D82326.1 gb:M95548.1 gb:L11696.1 gb:NM_000341.1 NM_000341 0003333 // amino acid transmembrane transport // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0015802 // basic amino acid transport // traceable author statement /// 0015811 // L-cystine transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // traceable author statement /// 0015174 // basic amino acid transmembrane transporter activity // traceable author statement /// 0015184 // L-cystine transmembrane transporter activity // traceable author statement /// 0043169 // cation binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205801_s_at NM_015376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015376.1 /DEF=Homo sapiens KIAA0846 protein (KIAA0846), mRNA. /FEA=mRNA /GEN=KIAA0846 /PROD=KIAA0846 protein /DB_XREF=gi:7662333 /UG=Hs.24024 KIAA0846 protein /FL=gb:AB020653.1 gb:NM_015376.1 NM_015376 RAS guanyl releasing protein 3 (calcium and DAG-regulated) RASGRP3 25780 NM_001139488 /// NM_015376 /// NM_170672 /// XM_005264246 /// XM_005264247 0000165 // MAPK cascade // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205802_at NM_003304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003304.1 /DEF=Homo sapiens transient receptor potential channel 1 (TRPC1), mRNA. /FEA=mRNA /GEN=TRPC1 /PROD=transient receptor potential channel 1 /DB_XREF=gi:4507684 /UG=Hs.250687 transient receptor potential channel 1 /FL=gb:NM_003304.1 NM_003304 transient receptor potential cation channel, subfamily C, member 1 TRPC1 7220 NM_001251845 /// NM_003304 /// XM_005247738 /// XM_005247739 /// XM_005247740 /// XR_241506 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0046541 // saliva secretion // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // not recorded /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 205803_s_at NM_003304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003304.1 /DEF=Homo sapiens transient receptor potential channel 1 (TRPC1), mRNA. /FEA=mRNA /GEN=TRPC1 /PROD=transient receptor potential channel 1 /DB_XREF=gi:4507684 /UG=Hs.250687 transient receptor potential channel 1 /FL=gb:NM_003304.1 NM_003304 transient receptor potential cation channel, subfamily C, member 1 TRPC1 7220 NM_001251845 /// NM_003304 /// XM_005247738 /// XM_005247739 /// XM_005247740 /// XR_241506 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0046541 // saliva secretion // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // not recorded /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 205804_s_at NM_025228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025228.1 /DEF=Homo sapiens hypothetical protein dJ434O14.3 (DJ434O14.3), mRNA. /FEA=mRNA /GEN=DJ434O14.3 /PROD=hypothetical protein dJ434O14.3 /DB_XREF=gi:13435126 /UG=Hs.261373 hypothetical protein dJ434O14.3 /FL=gb:NM_025228.1 NM_025228 TRAF3 interacting protein 3 TRAF3IP3 80342 NM_001287754 /// NM_025228 /// NR_109871 /// XM_005273279 /// XM_005273280 /// XR_247044 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 205805_s_at NM_005012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005012.1 /DEF=Homo sapiens receptor tyrosine kinase-like orphan receptor 1 (ROR1), mRNA. /FEA=mRNA /GEN=ROR1 /PROD=receptor tyrosine kinase-like orphan receptor 1 /DB_XREF=gi:4826867 /UG=Hs.274243 receptor tyrosine kinase-like orphan receptor 1 /FL=gb:M97675.1 gb:NM_005012.1 NM_005012 receptor tyrosine kinase-like orphan receptor 1 ROR1 4919 NM_001083592 /// NM_005012 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from physical interaction 205806_at NM_000327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000327.1 /DEF=Homo sapiens retinal outer segment membrane protein 1 (ROM1), mRNA. /FEA=mRNA /GEN=ROM1 /PROD=retinal outer segment membrane protein 1 /DB_XREF=gi:4506574 /UG=Hs.281564 retinal outer segment membrane protein 1 /FL=gb:L07894.1 gb:NM_000327.1 NM_000327 retinal outer segment membrane protein 1 ROM1 6094 NM_000327 0007155 // cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation 205807_s_at NM_020127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020127.1 /DEF=Homo sapiens tuftelin 1 (TUFT1), mRNA. /FEA=mRNA /GEN=TUFT1 /PROD=tuftelin 1 /DB_XREF=gi:9910595 /UG=Hs.283009 tuftelin 1 /FL=gb:AL136917.1 gb:AF254260.1 gb:NM_020127.1 NM_020127 tuftelin 1 TUFT1 7286 NM_001126337 /// NM_020127 /// XM_005245474 /// XM_006711525 0030282 // bone mineralization // non-traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0042476 // odontogenesis // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030345 // structural constituent of tooth enamel // non-traceable author statement 205808_at NM_004318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004318.1 /DEF=Homo sapiens aspartate beta-hydroxylase (ASPH), mRNA. /FEA=mRNA /GEN=ASPH /PROD=aspartate beta-hydroxylase /DB_XREF=gi:4757799 /UG=Hs.283664 aspartate beta-hydroxylase /FL=gb:U03109.1 gb:NM_004318.1 NM_004318 aspartate beta-hydroxylase ASPH 444 NM_001164750 /// NM_001164751 /// NM_001164752 /// NM_001164753 /// NM_001164754 /// NM_001164755 /// NM_001164756 /// NM_004318 /// NM_020164 /// NM_032466 /// NM_032467 /// NM_032468 /// XM_005251235 /// XM_005251236 /// XM_005251238 /// XM_005251239 /// XM_005251240 /// XM_005251241 /// XM_005251242 /// XM_005251243 /// XM_005251244 /// XM_005251246 /// XM_005251247 /// XM_005251248 /// XM_005251249 /// XM_005251250 /// XM_006716448 /// XM_006716449 0005513 // detection of calcium ion // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0018193 // peptidyl-amino acid modification // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0033198 // response to ATP // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1901879 // regulation of protein depolymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement /// 0034704 // calcium channel complex // traceable author statement 0004597 // peptide-aspartate beta-dioxygenase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205809_s_at BE504979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE504979 /FEA=EST /DB_XREF=gi:9707387 /DB_XREF=est:hz38g08.x1 /CLONE=IMAGE:3210302 /UG=Hs.288830 Wiskott-Aldrich syndrome-like /FL=gb:D88460.1 gb:NM_003941.1 BE504979 Wiskott-Aldrich syndrome-like WASL 8976 NM_003941 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006900 // membrane budding // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030050 // vesicle transport along actin filament // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051653 // spindle localization // inferred from electronic annotation /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from sequence or structural similarity /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205810_s_at NM_003941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003941.1 /DEF=Homo sapiens Wiskott-Aldrich syndrome-like (WASL), mRNA. /FEA=mRNA /GEN=WASL /PROD=Wiskott-Aldrich syndrome gene-like protein /DB_XREF=gi:4505322 /UG=Hs.288830 Wiskott-Aldrich syndrome-like /FL=gb:D88460.1 gb:NM_003941.1 NM_003941 Wiskott-Aldrich syndrome-like WASL 8976 NM_003941 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006900 // membrane budding // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030050 // vesicle transport along actin filament // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051653 // spindle localization // inferred from electronic annotation /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from sequence or structural similarity /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205811_at NM_007215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007215.1 /DEF=Homo sapiens polymerase (DNA directed), gamma 2, accessory subunit (POLG2), mRNA. /FEA=mRNA /GEN=POLG2 /PROD=polymerase (DNA directed), gamma 2, accessorysubunit /DB_XREF=gi:6005837 /UG=Hs.30541 polymerase (DNA directed), gamma 2, accessory subunit /FL=gb:BC000913.1 gb:U94703.1 gb:AF142992.1 gb:AF184344.1 gb:AF177201.1 gb:NM_007215.1 NM_007215 polymerase (DNA directed), gamma 2, accessory subunit POLG2 11232 NM_007215 /// XM_006721651 /// XR_243630 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement 0000262 // mitochondrial chromosome // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 205812_s_at NM_006588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006588.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 1C, member 2 (SULT1C2), mRNA. /FEA=mRNA /GEN=SULT1C2 /PROD=SULT1C sulfotransferase /DB_XREF=gi:5730070 /UG=Hs.312644 sulfotransferase family, cytosolic, 1C, member 2 /FL=gb:AF055584.1 gb:NM_006588.1 NM_006588 transmembrane emp24 protein transport domain containing 9 TMED9 54732 NM_017510 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // inferred from mutant phenotype /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction 205813_s_at NM_000429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000429.1 /DEF=Homo sapiens methionine adenosyltransferase I, alpha (MAT1A), mRNA. /FEA=mRNA /GEN=MAT1A /PROD=methionine adenosyltransferase I, alpha /DB_XREF=gi:4557736 /UG=Hs.323715 methionine adenosyltransferase I, alpha /FL=gb:NM_000429.1 gb:D49357.1 NM_000429 methionine adenosyltransferase I, alpha MAT1A 4143 NM_000429 /// XM_005269842 /// XM_005269843 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205814_at NM_000840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000840.1 /DEF=Homo sapiens glutamate receptor, metabotropic 3 (GRM3), mRNA. /FEA=mRNA /GEN=GRM3 /PROD=glutamate receptor, metabotropic 3 precursor /DB_XREF=gi:4504138 /UG=Hs.3786 glutamate receptor, metabotropic 3 /FL=gb:NM_000840.1 NM_000840 glutamate receptor, metabotropic 3 GRM3 2913 NM_000840 /// XM_005250290 /// XM_006715937 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097449 // astrocyte projection // inferred from electronic annotation 0001641 // group II metabotropic glutamate receptor activity // not recorded /// 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0008066 // glutamate receptor activity // traceable author statement 205815_at NM_002580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002580.1 /DEF=Homo sapiens pancreatitis-associated protein (PAP), mRNA. /FEA=mRNA /GEN=PAP /PROD=pancreatitis-associated protein /DB_XREF=gi:4505604 /UG=Hs.423 pancreatitis-associated protein /FL=gb:M84337.1 gb:D13510.1 gb:NM_002580.1 NM_002580 regenerating islet-derived 3 alpha REG3A 5068 NM_002580 /// NM_138937 /// NM_138938 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010838 // positive regulation of keratinocyte proliferation // inferred from sequence or structural similarity /// 0045617 // negative regulation of keratinocyte differentiation // inferred from sequence or structural similarity /// 0090303 // positive regulation of wound healing // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0030246 // carbohydrate binding // inferred from electronic annotation 205816_at NM_002214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002214.1 /DEF=Homo sapiens integrin, beta 8 (ITGB8), mRNA. /FEA=mRNA /GEN=ITGB8 /PROD=integrin, beta 8 /DB_XREF=gi:4504778 /UG=Hs.52620 integrin, beta 8 /FL=gb:M73780.1 gb:NM_002214.1 NM_002214 integrin, beta 8 ITGB8 3696 NM_002214 /// XM_005249751 /// XM_005249752 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0060674 // placenta blood vessel development // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation 205817_at NM_005982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005982.1 /DEF=Homo sapiens sine oculis homeobox (Drosophila) homolog 1 (SIX1), mRNA. /FEA=mRNA /GEN=SIX1 /PROD=sine oculis homeobox (Drosophila) homolog 1 /DB_XREF=gi:5174680 /UG=Hs.54416 sine oculis homeobox (Drosophila) homolog 1 /FL=gb:NM_005982.1 NM_005982 SIX homeobox 1 SIX1 6495 NM_005982 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001759 // organ induction // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021610 // facial nerve morphogenesis // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072095 // regulation of branch elongation involved in ureteric bud branching // inferred from sequence or structural similarity /// 0072107 // positive regulation of ureteric bud formation // inferred from sequence or structural similarity /// 0072172 // mesonephric tubule formation // inferred from sequence or structural similarity /// 0072193 // ureter smooth muscle cell differentiation // inferred from electronic annotation /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 2000729 // positive regulation of mesenchymal cell proliferation involved in ureter development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 205818_at NM_014618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014618.1 /DEF=Homo sapiens deleted in bladder cancer chromosome region candidate 1 (DBCCR1), mRNA. /FEA=mRNA /GEN=DBCCR1 /PROD=deleted in bladder cancer chromosome regioncandidate 1 /DB_XREF=gi:7657008 /UG=Hs.6090 deleted in bladder cancer chromosome region candidate 1 /FL=gb:AF027734.1 gb:NM_014618.1 NM_014618 bone morphogenetic protein/retinoic acid inducible neural-specific 1 BRINP1 1620 NM_014618 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 205819_at NM_006770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006770.1 /DEF=Homo sapiens macrophage receptor with collagenous structure (MARCO), mRNA. /FEA=mRNA /GEN=MARCO /PROD=macrophage receptor with collagenous structure /DB_XREF=gi:5803079 /UG=Hs.67726 macrophage receptor with collagenous structure /FL=gb:AF035819.1 gb:NM_006770.1 NM_006770 macrophage receptor with collagenous structure MARCO 8685 NM_006770 0002221 // pattern recognition receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0008329 // signaling pattern recognition receptor activity // traceable author statement 205820_s_at NM_000040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000040.1 /DEF=Homo sapiens apolipoprotein C-III (APOC3), mRNA. /FEA=mRNA /GEN=APOC3 /PROD=apolipoprotein C-III precursor /DB_XREF=gi:4557322 /UG=Hs.73849 apolipoprotein C-III /FL=gb:M28613.1 gb:M28614.1 gb:NM_000040.1 NM_000040 apolipoprotein C-III APOC3 345 NM_000040 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006642 // triglyceride mobilization // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010897 // negative regulation of triglyceride catabolic process // inferred from direct assay /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred by curator /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0010987 // negative regulation of high-density lipoprotein particle clearance // inferred from mutant phenotype /// 0010989 // negative regulation of low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043691 // reverse cholesterol transport // inferred by curator /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay /// 0060621 // negative regulation of cholesterol import // inferred from mutant phenotype /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005543 // phospholipid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred by curator /// 0030234 // enzyme regulator activity // inferred from direct assay /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0070653 // high-density lipoprotein particle receptor binding // inferred from physical interaction 205821_at NM_007360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007360.1 /DEF=Homo sapiens DNA segment on chromosome 12 (unique) 2489 expressed sequence (D12S2489E), mRNA. /FEA=mRNA /GEN=D12S2489E /PROD=NKG2-D type II integral membrane protein /DB_XREF=gi:6679051 /UG=Hs.74085 DNA segment on chromosome 12 (unique) 2489 expressed sequence /FL=gb:NM_007360.1 gb:AF260135.1 gb:AF260136.1 NM_007360 KLRC4-KLRK1 readthrough /// killer cell lectin-like receptor subfamily K, member 1 KLRC4-KLRK1 /// KLRK1 22914 /// 100528032 NM_001199805 /// NM_007360 0002223 // stimulatory C-type lectin receptor signaling pathway // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030101 // natural killer cell activation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032394 // MHC class Ib receptor activity // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205822_s_at NM_002130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002130.1 /DEF=Homo sapiens 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (HMGCS1), mRNA. /FEA=mRNA /GEN=HMGCS1 /PROD=3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1(soluble) /DB_XREF=gi:4504428 /UG=Hs.77910 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) /FL=gb:BC000297.1 gb:L25798.1 gb:NM_002130.1 NM_002130 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) HMGCS1 3157 NM_001098272 /// NM_002130 /// XM_005248295 0001101 // response to acid // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009645 // response to low light intensity stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014074 // response to purine-containing compound // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046690 // response to tellurium ion // inferred from electronic annotation /// 0055094 // response to lipoprotein particle // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004421 // hydroxymethylglutaryl-CoA synthase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043177 // organic acid binding // inferred from electronic annotation 205823_at AI824113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI824113 /FEA=EST /DB_XREF=gi:5444784 /DB_XREF=est:wj46d03.x1 /CLONE=IMAGE:2405861 /UG=Hs.78281 regulator of G-protein signalling 12 /FL=gb:AF035152.1 gb:NM_002926.1 AI824113 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from direct assay 205824_at NM_001541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001541.1 /DEF=Homo sapiens heat shock 27kD protein 2 (HSPB2), mRNA. /FEA=mRNA /GEN=HSPB2 /PROD=heat shock 27kD protein 2 /DB_XREF=gi:4504518 /UG=Hs.78846 heat shock 27kD protein 2 /FL=gb:D89617.1 gb:NM_001541.1 NM_001541 heat shock 27kDa protein 2 HSPB2 3316 NM_001541 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007525 // somatic muscle development // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement 205825_at NM_000439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000439.2 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 1 (PCSK1), mRNA. /FEA=mRNA /GEN=PCSK1 /PROD=proprotein convertase subtilisinkexin type 1 /DB_XREF=gi:4585713 /UG=Hs.78977 proprotein convertase subtilisinkexin type 1 /FL=gb:M90753.1 gb:NM_000439.2 NM_000439 proprotein convertase subtilisin/kexin type 1 PCSK1 5122 NM_000439 /// NM_001177875 /// NM_001177876 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // traceable author statement /// 0043043 // peptide biosynthetic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // not recorded /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205826_at NM_003970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003970.1 /DEF=Homo sapiens myomesin (M-protein) 2 (165kD) (MYOM2), mRNA. /FEA=mRNA /GEN=MYOM2 /PROD=myomesin 2 /DB_XREF=gi:4505314 /UG=Hs.79227 myomesin (M-protein) 2 (165kD) /FL=gb:NM_003970.1 NM_003970 myomesin 2 MYOM2 9172 NM_003970 /// XM_006716237 0006936 // muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0031430 // M band // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 205827_at NM_000729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000729.2 /DEF=Homo sapiens cholecystokinin (CCK), mRNA. /FEA=mRNA /GEN=CCK /PROD=cholecystokinin preproprotein /DB_XREF=gi:4755130 /UG=Hs.80247 cholecystokinin /FL=gb:NM_000729.2 NM_000729 cholecystokinin CCK 885 NM_000729 /// NM_001174138 0001662 // behavioral fear response // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from electronic annotation /// 0042755 // eating behavior // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043203 // axon hillock // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 205828_at NM_002422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002422.2 /DEF=Homo sapiens matrix metalloproteinase 3 (stromelysin 1, progelatinase) (MMP3), mRNA. /FEA=mRNA /GEN=MMP3 /PROD=matrix metalloproteinase 3 preproprotein /DB_XREF=gi:13027803 /UG=Hs.83326 matrix metalloproteinase 3 (stromelysin 1, progelatinase) /FL=gb:NM_002422.2 gb:J03209.1 NM_002422 matrix metallopeptidase 3 (stromelysin 1, progelatinase) MMP3 4314 NM_002422 0006508 // proteolysis // inferred from electronic annotation /// 0010727 // negative regulation of hydrogen peroxide metabolic process // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205829_at NM_000413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000413.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 1 (HSD17B1), mRNA. /FEA=mRNA /GEN=HSD17B1 /PROD=hydroxysteroid (17-beta) dehydrogenase 1 /DB_XREF=gi:4504500 /UG=Hs.85279 hydroxysteroid (17-beta) dehydrogenase 1 /FL=gb:M36263.1 gb:NM_000413.1 NM_000413 hydroxysteroid (17-beta) dehydrogenase 1 HSD17B1 3292 NM_000413 /// XM_005257292 /// XM_006721857 /// XM_006721858 /// XM_006721859 /// XM_006721860 /// XR_429889 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008210 // estrogen metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0061370 // testosterone biosynthetic process // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004303 // estradiol 17-beta-dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 205830_at NM_004362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004362.1 /DEF=Homo sapiens calmegin (CLGN), mRNA. /FEA=mRNA /GEN=CLGN /PROD=calmegin /DB_XREF=gi:4758003 /UG=Hs.86368 calmegin /FL=gb:D86322.1 gb:NM_004362.1 NM_004362 calmegin CLGN 1047 NM_001130675 /// NM_004362 /// XM_006714062 0006457 // protein folding // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 205831_at NM_001767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001767.1 /DEF=Homo sapiens CD2 antigen (p50), sheep red blood cell receptor (CD2), mRNA. /FEA=mRNA /GEN=CD2 /PROD=CD2 antigen (p50), sheep red blood cellreceptor /DB_XREF=gi:4502652 /UG=Hs.89476 CD2 antigen (p50), sheep red blood cell receptor /FL=gb:M16445.1 gb:M14362.1 gb:M16336.1 gb:NM_001767.1 NM_001767 CD2 molecule CD2 914 NM_001767 /// XM_005271319 /// XM_005271320 0001766 // membrane raft polarization // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0030887 // positive regulation of myeloid dendritic cell activation // non-traceable author statement /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0042110 // T cell activation // traceable author statement /// 0045580 // regulation of T cell differentiation // non-traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 1902715 // positive regulation of interferon-gamma secretion // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205832_at NM_016352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016352.1 /DEF=Homo sapiens carboxypeptidase A3 (LOC51200), mRNA. /FEA=mRNA /GEN=LOC51200 /PROD=carboxypeptidase A3 /DB_XREF=gi:10047105 /UG=Hs.93764 carboxypeptidase A3 /FL=gb:NM_016352.1 gb:AF095719.1 NM_016352 carboxypeptidase A4 CPA4 51200 NM_001163446 /// NM_016352 0006508 // proteolysis // inferred from electronic annotation /// 0016573 // histone acetylation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205833_s_at AI770098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI770098 /FEA=EST /DB_XREF=gi:5236553 /DB_XREF=est:wj30h12.x1 /CLONE=IMAGE:2404391 /UG=Hs.96744 prostate androgen-regulated transcript 1 /FL=gb:NM_016590.2 gb:AF163475.1 AI770098 prostate androgen-regulated transcript 1 (non-protein coding) PART1 25859 NM_001039499 /// NM_001040639 /// NR_024617 /// NR_028508 /// NR_028509 205834_s_at NM_016590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016590.2 /DEF=Homo sapiens prostate androgen-regulated transcript 1 (PART1), mRNA. /FEA=mRNA /GEN=PART1 /PROD=prostate androgen-regulated transcript 1protein /DB_XREF=gi:11496986 /UG=Hs.96744 prostate androgen-regulated transcript 1 /FL=gb:NM_016590.2 gb:AF163475.1 NM_016590 prostate androgen-regulated transcript 1 (non-protein coding) PART1 25859 NM_001039499 /// NM_001040639 /// NR_024617 /// NR_028508 /// NR_028509 205835_s_at AW975818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW975818 /FEA=EST /DB_XREF=gi:8167038 /DB_XREF=est:EST387927 /UG=Hs.104916 hypothetical protein FLJ21940 /FL=gb:NM_022828.1 AW975818 YTH domain containing 2 YTHDC2 64848 NM_022828 /// XM_005272052 /// XR_246540 0006200 // ATP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0044829 // positive regulation by host of viral genome replication // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from physical interaction 205836_s_at NM_022828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022828.1 /DEF=Homo sapiens hypothetical protein FLJ21940 (FLJ21940), mRNA. /FEA=mRNA /GEN=FLJ21940 /PROD=hypothetical protein FLJ21940 /DB_XREF=gi:12383069 /UG=Hs.104916 hypothetical protein FLJ21940 /FL=gb:NM_022828.1 NM_022828 YTH domain containing 2 YTHDC2 64848 NM_022828 /// XM_005272052 /// XR_246540 0006200 // ATP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0044829 // positive regulation by host of viral genome replication // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from physical interaction 205837_s_at BC005319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005319.1 /DEF=Homo sapiens, Similar to glycophorin A (includes MN blood group), clone MGC:12403, mRNA, complete cds. /FEA=mRNA /PROD=Similar to glycophorin A (includes MN bloodgroup) /DB_XREF=gi:13529076 /UG=Hs.108694 glycophorin A (includes MN blood group) /FL=gb:BC005319.1 gb:U00177.1 gb:L31860.1 gb:NM_002099.2 BC005319 glycophorin A (MNS blood group) GYPA 2993 NM_002099 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0047484 // regulation of response to osmotic stress // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205838_at NM_002099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002099.2 /DEF=Homo sapiens glycophorin A (includes MN blood group) (GYPA), mRNA. /FEA=mRNA /GEN=GYPA /PROD=glycophorin A precursor /DB_XREF=gi:8051602 /UG=Hs.108694 glycophorin A (includes MN blood group) /FL=gb:BC005319.1 gb:U00177.1 gb:L31860.1 gb:NM_002099.2 NM_002099 glycophorin A (MNS blood group) GYPA 2993 NM_002099 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0047484 // regulation of response to osmotic stress // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205839_s_at NM_004758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004758.1 /DEF=Homo sapiens peripheral benzodiazepine receptor-associated protein 1 (PRAX-1), mRNA. /FEA=mRNA /GEN=PRAX-1 /PROD=peripheral benzodiazepine receptor-associatedprotein 1 /DB_XREF=gi:4758955 /UG=Hs.112499 peripheral benzodiazepine receptor-associated protein 1 /FL=gb:AF039571.1 gb:NM_004758.1 NM_004758 benzodiazepine receptor (peripheral) associated protein 1 BZRAP1 9256 NM_001261835 /// NM_004758 /// NM_024418 /// XM_005257807 /// XM_006722173 /// XM_006722174 /// XM_006722175 /// XM_006722176 /// XM_006722177 /// XM_006722178 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030156 // benzodiazepine receptor binding // inferred from physical interaction 205840_x_at NM_000515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000515.2 /DEF=Homo sapiens growth hormone 1 (GH1), transcript variant 1, mRNA. /FEA=mRNA /GEN=GH1 /PROD=growth hormone 1, isoform 1 precursor /DB_XREF=gi:13027811 /UG=Hs.115352 growth hormone 1 /FL=gb:NM_000515.2 NM_000515 growth hormone 1 GH1 2688 NM_000515 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205841_at NM_004972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004972.2 /DEF=Homo sapiens Janus kinase 2 (a protein tyrosine kinase) (JAK2), mRNA. /FEA=mRNA /GEN=JAK2 /PROD=Janus kinase 2 /DB_XREF=gi:13325062 /UG=Hs.115541 Janus kinase 2 (a protein tyrosine kinase) /FL=gb:NM_004972.2 gb:AF005216.1 gb:AF058925.1 gb:AF001362.1 NM_004972 Janus kinase 2 JAK2 3717 NM_004972 /// XM_005251455 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007260 // tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007498 // mesoderm development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from electronic annotation /// 0030041 // actin filament polymerization // non-traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031959 // mineralocorticoid receptor signaling pathway // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034050 // host programmed cell death induced by symbiont // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035409 // histone H3-Y41 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0042506 // tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042508 // tyrosine phosphorylation of Stat1 protein // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042977 // activation of JAK2 kinase activity // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050867 // positive regulation of cell activation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060399 // positive regulation of growth hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0061180 // mammary gland epithelium development // inferred from sequence or structural similarity /// 0070671 // response to interleukin-12 // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005901 // caveola // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement /// 0045121 // membrane raft // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005131 // growth hormone receptor binding // inferred from sequence or structural similarity /// 0005143 // interleukin-12 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from electronic annotation /// 0035401 // histone kinase activity (H3-Y41 specific) // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 205842_s_at AF001362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001362.1 /DEF=Homo sapiens Jak2 kinase (JAK2) mRNA, complete cds. /FEA=mRNA /GEN=JAK2 /PROD=Jak2 kinase /DB_XREF=gi:3236321 /UG=Hs.115541 Janus kinase 2 (a protein tyrosine kinase) /FL=gb:NM_004972.2 gb:AF005216.1 gb:AF058925.1 gb:AF001362.1 AF001362 Janus kinase 2 JAK2 3717 NM_004972 /// XM_005251455 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007260 // tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007498 // mesoderm development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from electronic annotation /// 0030041 // actin filament polymerization // non-traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031959 // mineralocorticoid receptor signaling pathway // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034050 // host programmed cell death induced by symbiont // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035409 // histone H3-Y41 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0042506 // tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042508 // tyrosine phosphorylation of Stat1 protein // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042977 // activation of JAK2 kinase activity // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050867 // positive regulation of cell activation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060399 // positive regulation of growth hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0061180 // mammary gland epithelium development // inferred from sequence or structural similarity /// 0070671 // response to interleukin-12 // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005901 // caveola // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement /// 0045121 // membrane raft // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005131 // growth hormone receptor binding // inferred from sequence or structural similarity /// 0005143 // interleukin-12 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from electronic annotation /// 0035401 // histone kinase activity (H3-Y41 specific) // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 205843_x_at NM_000755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000755.1 /DEF=Homo sapiens carnitine acetyltransferase (CRAT), nuclear gene encoding mitochondrial protein, transcript variant mitochondrial, mRNA. /FEA=mRNA /GEN=CRAT /PROD=carnitine acetyltransferase precursor,mitochondrial isoform /DB_XREF=gi:4557486 /UG=Hs.12068 carnitine acetyltransferase /FL=gb:NM_000755.1 NM_000755 carnitine O-acetyltransferase CRAT 1384 NM_000755 /// NM_001257363 /// NM_004003 /// NM_144782 /// XM_005251706 /// XM_005251707 /// XM_005251708 /// XM_005251709 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004092 // carnitine O-acetyltransferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 205844_at NM_004666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004666.1 /DEF=Homo sapiens vanin 1 (VNN1), mRNA. /FEA=mRNA /GEN=VNN1 /PROD=vanin 1 /DB_XREF=gi:4759311 /UG=Hs.12114 vanin 1 /FL=gb:NM_004666.1 gb:U39664.1 NM_004666 vanin 1 VNN1 8876 NM_004666 0002526 // acute inflammatory response // inferred from sequence or structural similarity /// 0002544 // chronic inflammatory response // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // traceable author statement /// 0015939 // pantothenate metabolic process // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0017159 // pantetheine hydrolase activity // inferred from direct assay /// 0034235 // GPI anchor binding // traceable author statement 205845_at NM_021098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021098.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 1H subunit (CACNA1H), mRNA. /FEA=mRNA /GEN=CACNA1H /PROD=calcium channel, voltage-dependent, alpha 1Hsubunit /DB_XREF=gi:10864076 /UG=Hs.122359 calcium channel, voltage-dependent, alpha 1H subunit /FL=gb:NM_021098.1 gb:AF073931.1 gb:AF051946.2 NM_021098 calcium channel, voltage-dependent, T type, alpha 1H subunit CACNA1H 8912 NM_001005407 /// NM_021098 /// XM_005255652 /// XM_006720963 /// XM_006720964 /// XM_006720965 /// XM_006720966 /// XM_006720967 /// XM_006720968 /// XM_006720969 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007517 // muscle organ development // non-traceable author statement /// 0007520 // myoblast fusion // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0032342 // aldosterone biosynthetic process // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034651 // cortisol biosynthetic process // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035865 // cellular response to potassium ion // inferred from expression pattern /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded /// 2000344 // positive regulation of acrosome reaction // inferred from mutant phenotype 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction 205846_at NM_002837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002837.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, B (PTPRB), mRNA. /FEA=mRNA /GEN=PTPRB /PROD=protein tyrosine phosphatase, receptor type, B /DB_XREF=gi:4506304 /UG=Hs.123641 protein tyrosine phosphatase, receptor type, B /FL=gb:NM_002837.1 NM_002837 protein tyrosine phosphatase, receptor type, B PTPRB 5787 NM_001109754 /// NM_001206971 /// NM_001206972 /// NM_002837 /// XM_006719528 /// XM_006719529 /// XM_006719530 /// XR_245948 /// XR_245949 0001525 // angiogenesis // inferred from electronic annotation /// 0006470 // protein dephosphorylation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 205847_at NM_022119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022119.1 /DEF=Homo sapiens protease, serine, 26 (PRSS22), mRNA. /FEA=mRNA /GEN=PRSS22 /PROD=protease, serine, 26 /DB_XREF=gi:11545838 /UG=Hs.125532 protease, serine, 26 /FL=gb:AF321182.1 gb:NM_022119.1 gb:AB010779.1 NM_022119 protease, serine, 22 PRSS22 64063 NM_022119 /// XM_005255473 /// XM_006720915 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205848_at NM_005256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005256.1 /DEF=Homo sapiens growth arrest-specific 2 (GAS2), mRNA. /FEA=mRNA /GEN=GAS2 /PROD=growth arrest-specific 2 /DB_XREF=gi:4885252 /UG=Hs.129818 growth arrest-specific 2 /FL=gb:U95032.1 gb:NM_005256.1 NM_005256 growth arrest-specific 2 GAS2 2620 NM_001143830 /// NM_005256 /// NM_177553 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205849_s_at NM_006294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006294.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase binding protein (UQCRB), mRNA. /FEA=mRNA /GEN=UQCRB /PROD=ubiquinol-cytochrome c reductase bindingprotein /DB_XREF=gi:5454151 /UG=Hs.131255 ubiquinol-cytochrome c reductase binding protein /FL=gb:M22348.1 gb:NM_006294.1 NM_006294 ubiquinol-cytochrome c reductase binding protein UQCRB 7381 NM_001199975 /// NM_001254752 /// NM_006294 /// NR_045639 /// XM_006716652 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 205850_s_at NM_000814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000814.2 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 1, mRNA. /FEA=mRNA /GEN=GABRB3 /PROD=gamma-aminobutyric acid (GABA) A receptor, beta3, isoform 1 precursor /DB_XREF=gi:12548782 /UG=Hs.1440 gamma-aminobutyric acid (GABA) A receptor, beta 3 /FL=gb:NM_000814.2 gb:M82919.1 NM_000814 gamma-aminobutyric acid (GABA) A receptor, beta 3 GABRB3 2562 NM_000814 /// NM_001191320 /// NM_001191321 /// NM_001278631 /// NM_021912 /// NR_103801 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from direct assay /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 1902711 // GABA-A receptor complex // inferred from mutant phenotype /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0022851 // GABA-gated chloride ion channel activity // inferred from mutant phenotype /// 0022851 // GABA-gated chloride ion channel activity // inferred from sequence or structural similarity 205851_at BC001808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001808.1 /DEF=Homo sapiens, nucleoside diphosphate kinase type 6 (inhibitor of p53-induced apoptosis-alpha), clone MGC:1889, mRNA, complete cds. /FEA=mRNA /PROD=nucleoside diphosphate kinase type 6 (inhibitorof p53-induced apoptosis-alpha) /DB_XREF=gi:12804744 /UG=Hs.152717 nucleoside diphosphate kinase type 6 (inhibitor of p53-induced apoptosis-alpha) /FL=gb:BC001808.1 gb:BC001850.1 gb:U90449.1 gb:AF051941.1 gb:NM_005793.1 BC001808 NME/NM23 nucleoside diphosphate kinase 6 NME6 10201 NM_005793 /// XM_005264789 /// XM_005264790 /// XM_005264792 /// XM_005264793 /// XM_005264794 /// XM_006712921 /// XR_245088 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0045839 // negative regulation of mitosis // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205852_at R51311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R51311 /FEA=EST /DB_XREF=gi:813213 /DB_XREF=est:yg72e03.s1 /CLONE=IMAGE:38574 /UG=Hs.158460 cyclin-dependent kinase 5, regulatory subunit 2 (p39) /FL=gb:U34051.1 gb:NM_003936.1 R51311 cyclin-dependent kinase 5, regulatory subunit 2 (p39) CDK5R2 8941 NM_003936 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021722 // superior olivary nucleus maturation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016533 // cyclin-dependent protein kinase 5 holoenzyme complex // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016534 // cyclin-dependent protein kinase 5 activator activity // inferred from electronic annotation 205853_at NM_015872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015872.1 /DEF=Homo sapiens kruppel-related zinc finger protein hcKrox (LOC51043), mRNA. /FEA=mRNA /GEN=LOC51043 /PROD=kruppel-related zinc finger protein hcKrox /DB_XREF=gi:7705663 /UG=Hs.159265 kruppel-related zinc finger protein hcKrox /FL=gb:AF007833.1 gb:NM_015872.1 NM_015872 zinc finger and BTB domain containing 7B ZBTB7B 51043 NM_001252406 /// NM_001256455 /// NR_045515 /// NR_046206 /// NR_049765 /// XM_006711349 /// XM_006711350 /// XM_006711351 /// XM_006711352 /// XM_006711353 /// XM_006711354 /// XM_006711355 /// XM_006711356 /// XM_006711357 /// XM_006711358 /// XM_006711359 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043370 // regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043376 // regulation of CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205854_at AK024246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024246.1 /DEF=Homo sapiens cDNA FLJ14184 fis, clone NT2RP2005144, highly similar to Homo sapiens tubby like protein 3 (TULP3) mRNA. /FEA=mRNA /DB_XREF=gi:10436574 /UG=Hs.169084 tubby like protein 3 /FL=gb:AF045583.1 gb:NM_003324.1 AK024246 tubby like protein 3 TULP3 7289 NM_001160408 /// NM_003324 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021914 // negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from direct assay /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060434 // bronchus morphogenesis // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay /// 0097546 // ciliary base // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 205855_at NM_006991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006991.2 /DEF=Homo sapiens zinc finger protein 197 (ZNF197), mRNA. /FEA=mRNA /GEN=ZNF197 /PROD=zinc finger protein 197 /DB_XREF=gi:12056483 /UG=Hs.170341 zinc finger protein 197 /FL=gb:NM_006991.2 gb:AF011573.1 NM_006991 zinc finger protein 197 ZNF197 10168 NM_001024855 /// NM_006991 /// XM_005264783 /// XM_006712915 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 205856_at NM_015865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015865.1 /DEF=Homo sapiens solute carrier family 14 (urea transporter), member 1 (Kidd blood group) (SLC14A1), mRNA. /FEA=mRNA /GEN=SLC14A1 /PROD=RACH1 /DB_XREF=gi:7706676 /UG=Hs.171731 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) /FL=gb:U35735.1 gb:NM_015865.1 NM_015865 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) SLC14A1 6563 NM_001128588 /// NM_001146036 /// NM_001146037 /// NM_015865 /// XM_005258329 /// XM_005258332 /// XM_005258333 /// XM_006722526 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0015840 // urea transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071918 // urea transmembrane transport // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005372 // water transmembrane transporter activity // inferred from electronic annotation /// 0015204 // urea transmembrane transporter activity // traceable author statement /// 0015265 // urea channel activity // inferred from direct assay 205857_at AI269290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI269290 /FEA=EST /DB_XREF=gi:3888457 /DB_XREF=est:qi25g05.x1 /CLONE=IMAGE:1857560 /UG=Hs.1813 solute carrier family 18 (vesicular monoamine), member 2 /FL=gb:L14269.1 gb:L09118.1 gb:L23205.1 gb:NM_003054.1 AI269290 solute carrier family 18 (vesicular monoamine transporter), member 2 SLC18A2 6571 NM_003054 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006837 // serotonin transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015837 // amine transport // inferred from electronic annotation /// 0015844 // monoamine transport // traceable author statement /// 0016265 // death // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051589 // negative regulation of neurotransmitter transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071242 // cellular response to ammonium ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0005275 // amine transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008504 // monoamine transmembrane transporter activity // traceable author statement /// 0015222 // serotonin transmembrane transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation 205858_at NM_002507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002507.1 /DEF=Homo sapiens nerve growth factor receptor (TNFR superfamily, member 16) (NGFR), mRNA. /FEA=mRNA /GEN=NGFR /PROD=nerve growth factor receptor precursor /DB_XREF=gi:4505392 /UG=Hs.1827 nerve growth factor receptor (TNFR superfamily, member 16) /FL=gb:M14764.1 gb:NM_002507.1 NM_002507 nerve growth factor receptor NGFR 4804 NM_002507 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016048 // detection of temperature stimulus // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042488 // positive regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043588 // skin development // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0051799 // negative regulation of hair follicle development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001273 // regulation of glucose import in response to insulin stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005035 // death receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0048406 // nerve growth factor binding // inferred from electronic annotation 205859_at NM_004271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004271.1 /DEF=Homo sapiens MD-1, RP105-associated (MD-1), mRNA. /FEA=mRNA /GEN=MD-1 /PROD=MD-1, RP105-associated /DB_XREF=gi:4758707 /UG=Hs.184018 MD-1, RP105-associated /FL=gb:AF057178.2 gb:AB020499.1 gb:NM_004271.1 NM_004271 lymphocyte antigen 86 LY86 9450 NM_004271 /// XM_006715273 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from genetic interaction /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 205860_x_at NM_004476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004476.1 /DEF=Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), mRNA. /FEA=mRNA /GEN=FOLH1 /PROD=folate hydrolase (prostate-specific membraneantigen) 1 /DB_XREF=gi:4758397 /UG=Hs.1915 folate hydrolase (prostate-specific membrane antigen) 1 /FL=gb:M99487.1 gb:NM_004476.1 gb:AF176574.1 NM_004476 folate hydrolase (prostate-specific membrane antigen) 1 /// folate hydrolase 1B FOLH1 /// FOLH1B 2346 /// 219595 NM_001014986 /// NM_001193471 /// NM_001193472 /// NM_001193473 /// NM_004476 /// NM_153696 /// XM_005252839 /// XM_006718776 0006508 // proteolysis // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006760 // folic acid-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205861_at NM_003121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003121.1 /DEF=Homo sapiens Spi-B transcription factor (Spi-1PU.1 related) (SPIB), mRNA. /FEA=mRNA /GEN=SPIB /PROD=Spi-B transcription factor (Spi-1PU.1 related) /DB_XREF=gi:4507176 /UG=Hs.192861 Spi-B transcription factor (Spi-1PU.1 related) /FL=gb:NM_003121.1 NM_003121 Spi-B transcription factor (Spi-1/PU.1 related) SPIB 6689 NM_001243998 /// NM_001243999 /// NM_001244000 /// NM_003121 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0030225 // macrophage differentiation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205862_at NM_014668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014668.1 /DEF=Homo sapiens KIAA0575 gene product (KIAA0575), mRNA. /FEA=mRNA /GEN=KIAA0575 /PROD=KIAA0575 gene product /DB_XREF=gi:7662187 /UG=Hs.193914 KIAA0575 gene product /FL=gb:AB011147.1 gb:NM_014668.1 NM_014668 growth regulation by estrogen in breast cancer 1 GREB1 9687 NM_014668 /// NM_033090 /// NM_148903 /// XM_005246192 /// XM_005246195 /// XM_005246196 /// XM_005246197 /// XM_006711904 /// XM_006711905 /// XM_006711906 /// XM_006711907 /// XM_006711908 /// XR_426961 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 205863_at NM_005621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005621.1 /DEF=Homo sapiens S100 calcium-binding protein A12 (calgranulin C) (S100A12), mRNA. /FEA=mRNA /GEN=S100A12 /PROD=S100 calcium-binding protein A12 /DB_XREF=gi:5032058 /UG=Hs.19413 S100 calcium-binding protein A12 (calgranulin C) /FL=gb:D83664.1 gb:D49549.1 gb:NM_005621.1 NM_005621 S100 calcium binding protein A12 S100A12 6283 NM_005621 0002376 // immune system process // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045576 // mast cell activation // traceable author statement /// 0050663 // cytokine secretion // traceable author statement /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0050832 // defense response to fungus // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005507 // copper ion binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from physical interaction /// 0050786 // RAGE receptor binding // traceable author statement 205864_at NM_004173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004173.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 (SLC7A4), mRNA. /FEA=mRNA /GEN=SLC7A4 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 4 /DB_XREF=gi:4759137 /UG=Hs.197116 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 /FL=gb:NM_004173.1 NM_004173 solute carrier family 7, member 4 SLC7A4 6545 NM_004173 /// XM_005261716 /// XM_005261717 /// XM_006724309 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015802 // basic amino acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015174 // basic amino acid transmembrane transporter activity // traceable author statement 205865_at NM_005224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005224.1 /DEF=Homo sapiens dead ringer (Drosophila)-like 1 (DRIL1), mRNA. /FEA=mRNA /GEN=DRIL1 /PROD=dead ringer-like 1 /DB_XREF=gi:4885192 /UG=Hs.198515 dead ringer (Drosophila)-like 1 /FL=gb:U88047.1 gb:NM_005224.1 NM_005224 AT rich interactive domain 3A (BRIGHT-like) ARID3A 1820 NM_005224 /// XM_005259512 /// XM_005259513 /// XM_005259514 /// XM_005259515 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205866_at NM_003665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003665.1 /DEF=Homo sapiens ficolin (collagenfibrinogen domain-containing) 3 (Hakata antigen) (FCN3), mRNA. /FEA=mRNA /GEN=FCN3 /PROD=ficolin 3 precursor /DB_XREF=gi:4504330 /UG=Hs.21415 ficolin (collagenfibrinogen domain-containing) 3 (Hakata antigen) /FL=gb:D88587.1 gb:NM_003665.1 NM_003665 ficolin (collagen/fibrinogen domain containing) 3 FCN3 8547 NM_003665 /// NM_173452 0001867 // complement activation, lectin pathway // inferred from direct assay /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement 205867_at NM_002834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002834.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), mRNA. /FEA=mRNA /GEN=PTPN11 /PROD=protein tyrosine phosphatase, non-receptor type11 /DB_XREF=gi:13430845 /UG=Hs.22868 protein tyrosine phosphatase, non-receptor type 11 /FL=gb:NM_002834.1 gb:D13540.1 gb:L07527.1 gb:L03535.1 NM_002834 protein tyrosine phosphatase, non-receptor type 11 PTPN11 5781 NM_002834 /// NM_080601 /// XM_006719526 /// XM_006719527 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036302 // atrioventricular canal development // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051463 // negative regulation of cortisol secretion // inferred from electronic annotation /// 0060125 // negative regulation of growth hormone secretion // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 205868_s_at L07527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L07527.1 /DEF=Homo sapiens protein-tyrosine phosphatase mRNA, complete cds. /FEA=mRNA /PROD=protein-tyrosine phosphatase /DB_XREF=gi:292406 /UG=Hs.22868 protein tyrosine phosphatase, non-receptor type 11 /FL=gb:NM_002834.1 gb:D13540.1 gb:L07527.1 gb:L03535.1 L07527 protein tyrosine phosphatase, non-receptor type 11 PTPN11 5781 NM_002834 /// NM_080601 /// XM_006719526 /// XM_006719527 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036302 // atrioventricular canal development // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051463 // negative regulation of cortisol secretion // inferred from electronic annotation /// 0060125 // negative regulation of growth hormone secretion // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 205869_at NM_002769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002769.1 /DEF=Homo sapiens protease, serine, 1 (trypsin 1) (PRSS1), mRNA. /FEA=mRNA /GEN=PRSS1 /PROD=protease, serine, 1 (trypsin 1) /DB_XREF=gi:4506144 /UG=Hs.241395 protease, serine, 1 (trypsin 1) /FL=gb:NM_002769.1 gb:M22612.1 NM_002769 protease, serine, 1 (trypsin 1) /// protease, serine, 2 (trypsin 2) PRSS1 /// PRSS2 5644 /// 5645 NM_002769 /// NM_002770 /// XM_005276996 /// XM_005276998 /// XM_006716052 /// XM_006716053 /// XM_006725058 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205870_at NM_000623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000623.1 /DEF=Homo sapiens bradykinin receptor B2 (BDKRB2), mRNA. /FEA=mRNA /GEN=BDKRB2 /PROD=bradykinin receptor B2 /DB_XREF=gi:4557358 /UG=Hs.250882 bradykinin receptor B2 /FL=gb:M88714.1 gb:NM_000623.1 NM_000623 bradykinin receptor B2 BDKRB2 624 NM_000623 0006939 // smooth muscle contraction // inferred by curator /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0008015 // blood circulation // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0009651 // response to salt stress // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043114 // regulation of vascular permeability // inferred by curator /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from electronic annotation /// 1902239 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator // inferred from electronic annotation 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004947 // bradykinin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 205871_at BC005379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005379.1 /DEF=Homo sapiens, Similar to plasminogen, clone MGC:12496, mRNA, complete cds. /FEA=mRNA /PROD=Similar to plasminogen /DB_XREF=gi:13529238 /UG=Hs.262869 plasminogen-like /FL=gb:BC005379.1 gb:M93143.2 gb:NM_002665.1 BC005379 plasminogen-like B1 /// plasminogen-like B2 PLGLB1 /// PLGLB2 5342 /// 5343 NM_001032392 /// NM_002665 0005576 // extracellular region // inferred from electronic annotation 205872_x_at NM_022359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022359.1 /DEF=Homo sapiens similar to rat myomegalin (LOC64182), mRNA. /FEA=mRNA /GEN=LOC64182 /PROD=similar to rat myomegalin /DB_XREF=gi:11641276 /UG=Hs.265848 similar to rat myomegalin /FL=gb:AB042558.1 gb:NM_022359.1 NM_022359 phosphodiesterase 4D interacting protein PDE4DIP 9659 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_005272981 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 205873_at NM_004278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004278.1 /DEF=Homo sapiens phosphatidylinositol glycan, class L (PIGL), mRNA. /FEA=mRNA /GEN=PIGL /PROD=phosphatidylinositol glycan, class L /DB_XREF=gi:4758921 /UG=Hs.27008 phosphatidylinositol glycan, class L /FL=gb:AB017165.1 gb:NM_004278.1 NM_004278 phosphatidylinositol glycan anchor biosynthesis, class L PIGL 9487 NM_004278 /// XM_006721596 /// XR_243571 /// XR_429826 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // non-traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000225 // N-acetylglucosaminylphosphatidylinositol deacetylase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 205874_at NM_002220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002220.1 /DEF=Homo sapiens inositol 1,4,5-trisphosphate 3-kinase A (ITPKA), mRNA. /FEA=mRNA /GEN=ITPKA /PROD=1D-myo-inositol-trisphosphate 3-kinase A /DB_XREF=gi:4504788 /UG=Hs.2722 inositol 1,4,5-trisphosphate 3-kinase A /FL=gb:NM_002220.1 NM_002220 inositol-trisphosphate 3-kinase A ITPKA 3706 NM_002220 /// XM_005254348 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from electronic annotation /// 0097062 // dendritic spine maintenance // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043197 // dendritic spine // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from electronic annotation 205875_s_at NM_016381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016381.1 /DEF=Homo sapiens hypothetical protein (DKFZp434J0310), mRNA. /FEA=mRNA /GEN=DKFZp434J0310 /PROD=hypothetical protein /DB_XREF=gi:7705352 /UG=Hs.278408 hypothetical protein /FL=gb:AF319568.1 gb:AL137745.1 gb:NM_016381.1 NM_016381 ATR interacting protein /// three prime repair exonuclease 1 ATRIP /// TREX1 11277 /// 84126 NM_001271022 /// NM_001271023 /// NM_007248 /// NM_016381 /// NM_032166 /// NM_033627 /// NM_033628 /// NM_033629 /// NM_130384 0000077 // DNA damage checkpoint // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // inferred from sequence or structural similarity /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from sequence or structural similarity /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008296 // 3'-5'-exodeoxyribonuclease activity // inferred from sequence or structural similarity /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008408 // 3'-5' exonuclease activity // traceable author statement /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay /// 0032558 // adenyl deoxyribonucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // non-traceable author statement /// 0046872 // metal ion binding // traceable author statement 205876_at NM_002310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002310.2 /DEF=Homo sapiens leukemia inhibitory factor receptor (LIFR), mRNA. /FEA=mRNA /GEN=LIFR /PROD=leukemia inhibitory factor receptor precursor /DB_XREF=gi:6042197 /UG=Hs.2798 leukemia inhibitory factor receptor /FL=gb:NM_002310.2 NM_002310 leukemia inhibitory factor receptor alpha LIFR 3977 NM_001127671 /// NM_002310 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004923 // leukemia inhibitory factor receptor activity // inferred from direct assay /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction 205877_s_at NM_017590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017590.1 /DEF=Homo sapiens hypothetical protein DKFZp434K0920 (DKFZp434K0920), mRNA. /FEA=mRNA /GEN=DKFZp434K0920 /PROD=hypothetical protein DKFZp434K0920 /DB_XREF=gi:8922144 /UG=Hs.279922 hypothetical protein DKFZp434K0920 /FL=gb:NM_017590.1 NM_017590 zinc finger CCCH-type containing 7B ZC3H7B 23264 NM_017590 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205878_at NM_002702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002702.1 /DEF=Homo sapiens POU domain, class 6, transcription factor 1 (POU6F1), mRNA. /FEA=mRNA /GEN=POU6F1 /PROD=POU domain, class 6, transcription factor 1 /DB_XREF=gi:4505968 /UG=Hs.2815 POU domain, class 6, transcription factor 1 /FL=gb:NM_002702.1 NM_002702 POU class 6 homeobox 1 POU6F1 5463 NM_002702 /// NR_026893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205879_x_at BC004257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004257.1 /DEF=Homo sapiens, ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease), clone MGC:10752, mRNA, complete cds. /FEA=mRNA /PROD=ret proto-oncogene (multiple endocrine neoplasiaMEN2A, MEN2B and medullary thyroid carcinoma 1,Hirschsprung disease) /DB_XREF=gi:13279040 /UG=Hs.287270 ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease) /FL=gb:NM_020630.1 gb:BC004257.1 BC004257 ret proto-oncogene RET 5979 NM_000323 /// NM_020629 /// NM_020630 /// NM_020975 /// XM_006717936 0000165 // MAPK cascade // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007018 // microtubule-based movement // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0035617 // stress granule disassembly // inferred from electronic annotation /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005871 // kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205880_at NM_002742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002742.1 /DEF=Homo sapiens protein kinase C, mu (PRKCM), mRNA. /FEA=mRNA /GEN=PRKCM /PROD=protein kinase C, mu /DB_XREF=gi:4506074 /UG=Hs.2891 protein kinase C, mu /FL=gb:NM_002742.1 NM_002742 protein kinase D1 PRKD1 5587 NM_002742 /// XM_005267859 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010837 // regulation of keratinocyte proliferation // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from genetic interaction /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from genetic interaction /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from genetic interaction /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from genetic interaction /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from genetic interaction /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 1901727 // positive regulation of histone deacetylase activity // inferred from genetic interaction /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype /// 2001044 // regulation of integrin-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 205881_at NM_003426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003426.1 /DEF=Homo sapiens zinc finger protein 74 (Cos52) (ZNF74), mRNA. /FEA=mRNA /GEN=ZNF74 /PROD=zinc finger protein 74 (Cos52) /DB_XREF=gi:4508030 /UG=Hs.3057 zinc finger protein 74 (Cos52) /FL=gb:NM_003426.1 NM_003426 zinc finger protein 74 ZNF74 7625 NM_001256523 /// NM_001256524 /// NM_001256525 /// NM_003426 /// NR_046282 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205882_x_at AI818488 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI818488 /FEA=EST /DB_XREF=gi:5437567 /DB_XREF=est:wk60e04.x1 /CLONE=IMAGE:2419806 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:NM_016824.1 AI818488 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 205883_at NM_006006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006006.1 /DEF=Homo sapiens zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) (ZNF145), mRNA. /FEA=mRNA /GEN=ZNF145 /PROD=zinc finger protein 145 (Kruppel-like, expressedin promyelocytic leukemia) /DB_XREF=gi:5174752 /UG=Hs.37096 zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) /FL=gb:NM_006006.1 NM_006006 zinc finger and BTB domain containing 16 ZBTB16 7704 NM_001018011 /// NM_006006 /// XM_005271658 /// XM_006718899 0001501 // skeletal system development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0051216 // cartilage development // inferred from direct assay /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205884_at NM_000885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000885.2 /DEF=Homo sapiens integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), mRNA. /FEA=mRNA /GEN=ITGA4 /PROD=integrin alpha 4 precursor /DB_XREF=gi:6006032 /UG=Hs.40034 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) /FL=gb:NM_000885.2 gb:L12002.1 NM_000885 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) ITGA4 3676 NM_000885 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0060324 // face development // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 205885_s_at L12002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12002.1 /DEF=Human integrin alpha 4 subunit mRNA, complete cds. /FEA=mRNA /GEN=ITGA4 /PROD=integrin alpha 4 subunit /DB_XREF=gi:903743 /UG=Hs.40034 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) /FL=gb:NM_000885.2 gb:L12002.1 L12002 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) ITGA4 3676 NM_000885 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0060324 // face development // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 205886_at NM_006507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006507.1 /DEF=Homo sapiens regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein) (REG1B), mRNA. /FEA=mRNA /GEN=REG1B /PROD=regenerating islet-derived 1 beta (pancreaticstone protein, pancreatic thread protein) /DB_XREF=gi:10835247 /UG=Hs.4158 regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein) /FL=gb:NM_006507.1 gb:D16816.1 NM_006507 regenerating islet-derived 1 beta REG1B 5968 NM_006507 0008283 // cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0030246 // carbohydrate binding // inferred from electronic annotation 205887_x_at NM_002439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002439.1 /DEF=Homo sapiens mutS (E. coli) homolog 3 (MSH3), mRNA. /FEA=mRNA /GEN=MSH3 /PROD=mutS (E. coli) homolog 3 /DB_XREF=gi:4505248 /UG=Hs.42674 mutS (E. coli) homolog 3 /FL=gb:U61981.1 gb:NM_002439.1 NM_002439 mutS homolog 3 MSH3 4437 NM_002439 0000710 // meiotic mismatch repair // not recorded /// 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // not recorded /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000228 // nuclear chromosome // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032302 // MutSbeta complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000403 // Y-form DNA binding // not recorded /// 0000404 // heteroduplex DNA loop binding // not recorded /// 0000406 // double-strand/single-strand DNA junction binding // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032139 // dinucleotide insertion or deletion binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032181 // dinucleotide repeat insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay 205888_s_at AI962693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962693 /FEA=EST /DB_XREF=gi:5755406 /DB_XREF=est:wq55a09.x1 /CLONE=IMAGE:2475160 /UG=Hs.43107 KIAA0555 gene product /FL=gb:AB011127.1 gb:NM_014790.1 AI962693 janus kinase and microtubule interacting protein 2 JAKMIP2 9832 NM_001270934 /// NM_001270941 /// NM_001282282 /// NM_014790 0016310 // phosphorylation // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation 205889_s_at NM_014790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014790.1 /DEF=Homo sapiens KIAA0555 gene product (KIAA0555), mRNA. /FEA=mRNA /GEN=KIAA0555 /PROD=KIAA0555 gene product /DB_XREF=gi:7662177 /UG=Hs.43107 KIAA0555 gene product /FL=gb:AB011127.1 gb:NM_014790.1 NM_014790 janus kinase and microtubule interacting protein 2 JAKMIP2 9832 NM_001270934 /// NM_001270941 /// NM_001282282 /// NM_014790 0016310 // phosphorylation // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation 205890_s_at NM_006398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006398.1 /DEF=Homo sapiens diubiquitin (UBD), mRNA. /FEA=mRNA /GEN=UBD /PROD=diubiquitin /DB_XREF=gi:5454143 /UG=Hs.44532 diubiquitin /FL=gb:NM_006398.1 NM_006398 gamma-aminobutyric acid (GABA) B receptor, 1 /// ubiquitin D GABBR1 /// UBD 2550 /// 10537 NM_001470 /// NM_006398 /// NM_021903 /// NM_021904 /// NM_021905 /// XM_005248982 /// XM_005272785 /// XM_005274841 /// XM_005274931 /// XM_005275088 /// XM_005275227 /// XM_005275363 /// XM_006715047 /// XM_006725030 /// XM_006725477 /// XM_006725691 /// XM_006725807 /// XM_006725901 /// XM_006725988 /// XR_241884 /// XR_246960 /// XR_247352 /// XR_247386 /// XR_247400 /// XR_430672 /// XR_430972 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0032446 // protein modification by small protein conjugation // non-traceable author statement /// 0034341 // response to interferon-gamma // inferred from expression pattern /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0043011 // myeloid dendritic cell differentiation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 205891_at NM_000676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000676.1 /DEF=Homo sapiens adenosine A2b receptor (ADORA2B), mRNA. /FEA=mRNA /GEN=ADORA2B /PROD=adenosine A2b receptor /DB_XREF=gi:4501950 /UG=Hs.45743 adenosine A2b receptor /FL=gb:M97759.1 gb:NM_000676.1 NM_000676 adenosine A2b receptor ADORA2B 136 NM_000676 0000187 // activation of MAPK activity // traceable author statement /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0002882 // positive regulation of chronic inflammatory response to non-antigenic stimulus // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007588 // excretion // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001609 // G-protein coupled adenosine receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 205892_s_at NM_001443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001443.1 /DEF=Homo sapiens fatty acid binding protein 1, liver (FABP1), mRNA. /FEA=mRNA /GEN=FABP1 /PROD=fatty acid binding protein 1, liver /DB_XREF=gi:4557576 /UG=Hs.5241 fatty acid binding protein 1, liver /FL=gb:M10050.1 gb:M10617.1 gb:NM_001443.1 NM_001443 fatty acid binding protein 1, liver FABP1 2168 NM_001443 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005324 // long-chain fatty acid transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from direct assay /// 0032052 // bile acid binding // inferred from electronic annotation 205893_at NM_014932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014932.1 /DEF=Homo sapiens neuroligin 1 (NLGN1), mRNA. /FEA=mRNA /GEN=NLGN1 /PROD=neuroligin 1 /DB_XREF=gi:7662469 /UG=Hs.71132 neuroligin 1 /FL=gb:AB028993.1 gb:NM_014932.1 NM_014932 neuroligin 1 NLGN1 22871 NM_014932 /// XM_005247232 /// XM_005247233 /// XM_005247234 /// XM_005247235 /// XM_005247236 /// XM_005247237 /// XM_006713540 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007416 // synapse assembly // not recorded /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // inferred from sequence or structural similarity /// 0016339 // calcium-dependent cell-cell adhesion // inferred from sequence or structural similarity /// 0023041 // neuronal signal transduction // traceable author statement /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0035418 // protein localization to synapse // inferred from sequence or structural similarity /// 0045184 // establishment of protein localization // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048789 // cytoskeletal matrix organization at active zone // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060999 // positive regulation of dendritic spine development // inferred from sequence or structural similarity /// 0072553 // terminal button organization // inferred from sequence or structural similarity /// 0097091 // synaptic vesicle clustering // inferred from sequence or structural similarity /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from sequence or structural similarity /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from sequence or structural similarity /// 0097115 // neurexin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 1900029 // positive regulation of ruffle assembly // inferred from sequence or structural similarity /// 1900244 // positive regulation of synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000302 // positive regulation of synaptic vesicle exocytosis // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // not recorded /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0032433 // filopodium tip // inferred from sequence or structural similarity /// 0045202 // synapse // not recorded /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // traceable author statement 0004872 // receptor activity // not recorded /// 0004872 // receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042043 // neurexin family protein binding // not recorded /// 0042043 // neurexin family protein binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 205894_at NM_000047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000047.1 /DEF=Homo sapiens arylsulfatase E (chondrodysplasia punctata 1) (ARSE), mRNA. /FEA=mRNA /GEN=ARSE /PROD=arylsulfatase E precursor /DB_XREF=gi:4502240 /UG=Hs.74131 arylsulfatase E (chondrodysplasia punctata 1) /FL=gb:NM_000047.1 gb:X83573.1 NM_000047 arylsulfatase E (chondrodysplasia punctata 1) ARSE 415 NM_000047 /// NM_001282628 /// NM_001282631 /// XM_005274518 /// XM_005274519 /// XM_005274521 0001501 // skeletal system development // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205895_s_at NM_004741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004741.1 /DEF=Homo sapiens nucleolar phosphoprotein p130 (P130), mRNA. /FEA=mRNA /GEN=P130 /PROD=nucleolar phosphoprotein p130 /DB_XREF=gi:4758859 /UG=Hs.75337 nucleolar phosphoprotein p130 /FL=gb:BC001883.1 gb:NM_004741.1 NM_004741 nucleolar and coiled-body phosphoprotein 1 NOLC1 9221 NM_001284388 /// NM_001284389 /// NM_004741 /// XM_005270273 0006364 // rRNA processing // traceable author statement /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205896_at NM_003059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003059.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 4 (SLC22A4), mRNA. /FEA=mRNA /GEN=SLC22A4 /PROD=solute carrier family 22 (organic cationtransporter), member 4 /DB_XREF=gi:4507002 /UG=Hs.77239 solute carrier family 22 (organic cation transporter), member 4 /FL=gb:AB007448.1 gb:NM_003059.1 NM_003059 solute carrier family 22 (organic cation/zwitterion transporter), member 4 SLC22A4 6583 NM_003059 /// XM_006714675 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007589 // body fluid secretion // traceable author statement /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0015695 // organic cation transport // traceable author statement /// 0015697 // quaternary ammonium group transport // inferred from direct assay /// 0015879 // carnitine transport // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902603 // carnitine transmembrane transport // inferred from direct assay /// 1902603 // carnitine transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008513 // secondary active organic cation transmembrane transporter activity // traceable author statement /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015226 // carnitine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015491 // cation:cation antiporter activity // inferred from direct assay /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction 205897_at NM_004554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004554.1 /DEF=Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (NFATC4), mRNA. /FEA=mRNA /GEN=NFATC4 /PROD=nuclear factor of activated T-cells,cytoplasmic, calcineurin-dependent 4 /DB_XREF=gi:4758801 /UG=Hs.77810 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 /FL=gb:NM_004554.1 gb:L41066.1 NM_004554 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 NFATC4 4776 NM_001136022 /// NM_001198965 /// NM_001198966 /// NM_001198967 /// NM_001288802 /// NM_004554 /// XM_006720153 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation 205898_at U20350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20350.1 /DEF=Human G protein-coupled receptor V28 mRNA, complete cds. /FEA=mRNA /PROD=V28 /DB_XREF=gi:665580 /UG=Hs.78913 chemokine (C-X3-C) receptor 1 /FL=gb:NM_001337.1 gb:U20350.1 gb:U28934.1 U20350 chemokine (C-X3-C motif) receptor 1 CX3CR1 1524 NM_001171171 /// NM_001171172 /// NM_001171174 /// NM_001337 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016495 // C-X3-C chemokine receptor activity // inferred from electronic annotation 205899_at NM_003914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003914.1 /DEF=Homo sapiens cyclin A1 (CCNA1), mRNA. /FEA=mRNA /GEN=CCNA1 /PROD=cyclin A1 /DB_XREF=gi:4502610 /UG=Hs.79378 cyclin A1 /FL=gb:U66838.1 gb:NM_003914.1 NM_003914 cyclin A1 CCNA1 8900 NM_001111045 /// NM_001111046 /// NM_001111047 /// NM_003914 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007141 // male meiosis I // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 205900_at NM_006121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006121.1 /DEF=Homo sapiens keratin 1 (epidermolytic hyperkeratosis) (KRT1), mRNA. /FEA=mRNA /GEN=KRT1 /PROD=keratin 1 (epidermolytic hyperkeratosis) /DB_XREF=gi:5174490 /UG=Hs.80828 keratin 1 (epidermolytic hyperkeratosis) /FL=gb:NM_006121.1 NM_006121 keratin 1 KRT1 3848 NM_006121 0001867 // complement activation, lectin pathway // inferred from physical interaction /// 0001895 // retina homeostasis // inferred from expression pattern /// 0006979 // response to oxidative stress // non-traceable author statement /// 0042730 // fibrinolysis // non-traceable author statement /// 0045765 // regulation of angiogenesis // non-traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from physical interaction 205901_at NM_006228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006228.2 /DEF=Homo sapiens prepronociceptin (PNOC), mRNA. /FEA=mRNA /GEN=PNOC /PROD=prepronociceptin /DB_XREF=gi:11079650 /UG=Hs.89040 prepronociceptin /FL=gb:NM_006228.2 gb:U48263.1 NM_006228 prepronociceptin PNOC 5368 NM_001284244 /// NM_006228 /// XM_005273532 /// XM_005273533 0007165 // signal transduction // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007600 // sensory perception // traceable author statement 0005576 // extracellular region // traceable author statement 0001515 // opioid peptide activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 205902_at AJ251016 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ251016.1 /DEF=Homo sapiens mRNA for calcium-activated potassium channel SK3 (K3 (KCNN3) gene). /FEA=mRNA /GEN=K3 (KCNN3) /PROD=SK3 protein /DB_XREF=gi:6453381 /UG=Hs.89230 potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 3 /FL=gb:AF031815.1 gb:NM_002249.1 AJ251016 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 KCNN3 3782 NM_001204087 /// NM_002249 /// NM_170782 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0071805 // potassium ion transmembrane transport // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0044297 // cell body // inferred from electronic annotation 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // inferred from electronic annotation /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205903_s_at NM_002249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002249.1 /DEF=Homo sapiens potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 3 (KCNN3), mRNA. /FEA=mRNA /GEN=KCNN3 /PROD=potassium intermediatesmall conductancecalcium-activated channel, subfamily N, member 3 /DB_XREF=gi:4504856 /UG=Hs.89230 potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 3 /FL=gb:AF031815.1 gb:NM_002249.1 NM_002249 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 KCNN3 3782 NM_001204087 /// NM_002249 /// NM_170782 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0071805 // potassium ion transmembrane transport // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0044297 // cell body // inferred from electronic annotation 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // inferred from electronic annotation /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205904_at NM_000247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000247.1 /DEF=Homo sapiens MHC class I polypeptide-related sequence A (MICA), mRNA. /FEA=mRNA /GEN=MICA /PROD=MHC class I chain-related gene A protein /DB_XREF=gi:4557750 /UG=Hs.90598 MHC class I polypeptide-related sequence A /FL=gb:NM_000247.1 gb:L14848.1 NM_000247 MHC class I polypeptide-related sequence A MICA 100507436 NM_000247 /// NM_001177519 /// NM_001289152 /// NM_001289153 /// NM_001289154 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002418 // immune response to tumor cell // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0009408 // response to heat // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042267 // natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0046629 // gamma-delta T cell activation // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // inferred from direct assay /// 0046703 // natural killer cell lectin-like receptor binding // inferred from direct assay /// 0046703 // natural killer cell lectin-like receptor binding // inferred from physical interaction 205905_s_at NM_000247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000247.1 /DEF=Homo sapiens MHC class I polypeptide-related sequence A (MICA), mRNA. /FEA=mRNA /GEN=MICA /PROD=MHC class I chain-related gene A protein /DB_XREF=gi:4557750 /UG=Hs.90598 MHC class I polypeptide-related sequence A /FL=gb:NM_000247.1 gb:L14848.1 NM_000247 MHC class I polypeptide-related sequence A /// MHC class I polypeptide-related sequence B MICA /// MICB 4277 /// 100507436 NM_000247 /// NM_001177519 /// NM_001289152 /// NM_001289153 /// NM_001289154 /// NM_001289160 /// NM_001289161 /// NM_005931 /// XM_006726002 /// XM_006726095 0001913 // T cell mediated cytotoxicity // not recorded /// 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002418 // immune response to tumor cell // inferred from direct assay /// 0002429 // immune response-activating cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from direct assay /// 0009408 // response to heat // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0032526 // response to retinoic acid // inferred from direct assay /// 0042267 // natural killer cell mediated cytotoxicity // not recorded /// 0042267 // natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0046629 // gamma-delta T cell activation // inferred from direct assay /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030881 // beta-2-microglobulin binding // inferred from direct assay /// 0046703 // natural killer cell lectin-like receptor binding // inferred from direct assay /// 0046703 // natural killer cell lectin-like receptor binding // inferred from physical interaction 205906_at NM_001454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001454.1 /DEF=Homo sapiens forkhead box J1 (FOXJ1), mRNA. /FEA=mRNA /GEN=FOXJ1 /PROD=forkhead box J1 /DB_XREF=gi:4557023 /UG=Hs.93974 forkhead box J1 /FL=gb:U69537.1 gb:NM_001454.1 NM_001454 forkhead box J1 FOXJ1 2302 NM_001454 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001947 // heart looping // not recorded /// 0002508 // central tolerance induction // inferred from sequence or structural similarity /// 0002635 // negative regulation of germinal center formation // not recorded /// 0002635 // negative regulation of germinal center formation // inferred from sequence or structural similarity /// 0002897 // positive regulation of central B cell tolerance induction // not recorded /// 0002897 // positive regulation of central B cell tolerance induction // inferred from sequence or structural similarity /// 0002924 // negative regulation of humoral immune response mediated by circulating immunoglobulin // not recorded /// 0002924 // negative regulation of humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // non-traceable author statement /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007420 // brain development // non-traceable author statement /// 0030036 // actin cytoskeleton organization // not recorded /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032862 // activation of Rho GTPase activity // not recorded /// 0032862 // activation of Rho GTPase activity // inferred from sequence or structural similarity /// 0033085 // negative regulation of T cell differentiation in thymus // not recorded /// 0033085 // negative regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035089 // establishment of apical/basal cell polarity // not recorded /// 0035089 // establishment of apical/basal cell polarity // inferred from sequence or structural similarity /// 0035502 // metanephric part of ureteric bud development // inferred from expression pattern /// 0042130 // negative regulation of T cell proliferation // not recorded /// 0042384 // cilium assembly // not recorded /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045409 // negative regulation of interleukin-6 biosynthetic process // not recorded /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050869 // negative regulation of B cell activation // not recorded /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // not recorded /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060428 // lung epithelium development // non-traceable author statement /// 0060429 // epithelium development // inferred from sequence or structural similarity /// 0060972 // left/right pattern formation // not recorded /// 0072016 // glomerular parietal epithelial cell development // inferred from expression pattern /// 1901248 // positive regulation of lung ciliated cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205907_s_at AI765819 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI765819 /FEA=EST /DB_XREF=gi:5232317 /DB_XREF=est:wi84g05.x1 /CLONE=IMAGE:2400056 /UG=Hs.94070 osteomodulin /FL=gb:AB000114.1 gb:NM_005014.1 AI765819 osteomodulin OMD 4958 NM_005014 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation 205908_s_at NM_005014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005014.1 /DEF=Homo sapiens osteomodulin (OMD), mRNA. /FEA=mRNA /GEN=OMD /PROD=osteomodulin /DB_XREF=gi:4826875 /UG=Hs.94070 osteomodulin /FL=gb:AB000114.1 gb:NM_005014.1 NM_005014 osteomodulin OMD 4958 NM_005014 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation 205909_at NM_002692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002692.1 /DEF=Homo sapiens polymerase (DNA directed), epsilon 2 (POLE2), mRNA. /FEA=mRNA /GEN=POLE2 /PROD=polymerase (DNA directed), epsilon 2 /DB_XREF=gi:4505934 /UG=Hs.99185 polymerase (DNA directed), epsilon 2 /FL=gb:AF025840.1 gb:AF036899.1 gb:NM_002692.1 NM_002692 polymerase (DNA directed), epsilon 2, accessory subunit POLE2 5427 NM_001197330 /// NM_001197331 /// NM_002692 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0008622 // epsilon DNA polymerase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 205910_s_at NM_001807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001807.1 /DEF=Homo sapiens carboxyl ester lipase (bile salt-stimulated lipase) (CEL), mRNA. /FEA=mRNA /GEN=CEL /PROD=carboxyl ester lipase (bile salt-stimulatedlipase) /DB_XREF=gi:4502770 /UG=Hs.99918 carboxyl ester lipase (bile salt-stimulated lipase) /FL=gb:M85201.1 gb:NM_001807.1 NM_001807 carboxyl ester lipase CEL 1056 NM_001807 0006629 // lipid metabolic process // non-traceable author statement /// 0006641 // triglyceride metabolic process // inferred by curator /// 0006707 // cholesterol catabolic process // inferred from direct assay /// 0006707 // cholesterol catabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0018350 // protein esterification // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030157 // pancreatic juice secretion // inferred from direct assay /// 0030299 // intestinal cholesterol absorption // non-traceable author statement /// 0042363 // fat-soluble vitamin catabolic process // non-traceable author statement /// 0044241 // lipid digestion // traceable author statement /// 0044258 // intestinal lipid catabolic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046514 // ceramide catabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004771 // sterol esterase activity // non-traceable author statement /// 0004771 // sterol esterase activity // traceable author statement /// 0004806 // triglyceride lipase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // non-traceable author statement /// 0016298 // lipase activity // traceable author statement /// 0016787 // hydrolase activity // traceable author statement /// 0047372 // acylglycerol lipase activity // traceable author statement 205911_at NM_000316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000316.1 /DEF=Homo sapiens parathyroid hormone receptor 1 (PTHR1), mRNA. /FEA=mRNA /GEN=PTHR1 /PROD=parathyroid hormone receptor 1 /DB_XREF=gi:4506270 /UG=Hs.1019 parathyroid hormone receptor 1 /FL=gb:L04308.1 gb:NM_000316.1 gb:U17418.1 NM_000316 parathyroid hormone 1 receptor PTH1R 5745 NM_000316 /// NM_001184744 /// XM_005265342 /// XM_005265343 /// XM_005265344 /// XM_006713272 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred by curator /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004991 // parathyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay 205912_at NM_000936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000936.1 /DEF=Homo sapiens pancreatic lipase (PNLIP), mRNA. /FEA=mRNA /GEN=PNLIP /PROD=pancreatic lipase /DB_XREF=gi:10834999 /UG=Hs.102876 pancreatic lipase /FL=gb:NM_000936.1 gb:M93285.1 gb:J05125.1 NM_000936 pancreatic lipase PNLIP 5406 NM_000936 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from electronic annotation /// 0044241 // lipid digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205913_at NM_002666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002666.1 /DEF=Homo sapiens perilipin (PLIN), mRNA. /FEA=mRNA /GEN=PLIN /PROD=perilipin /DB_XREF=gi:4505884 /UG=Hs.103253 perilipin /FL=gb:AB005293.1 gb:NM_002666.1 NM_002666 perilipin 1 PLIN1 5346 NM_001145311 /// NM_002666 /// XM_005254934 0006629 // lipid metabolic process // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005811 // lipid particle // non-traceable author statement /// 0005811 // lipid particle // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // non-traceable author statement 205914_s_at NM_007327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007327.1 /DEF=Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, mRNA. /FEA=mRNA /GEN=GRIN1 /PROD=NMDA receptor 1, isoform NR1-3 precursor /DB_XREF=gi:11038636 /UG=Hs.105 glutamate receptor, ionotropic, N-methyl D-aspartate 1 /FL=gb:NM_007327.1 gb:D13515.1 NM_007327 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRIN1 2902 NM_000832 /// NM_001185090 /// NM_001185091 /// NM_007327 /// NM_021569 /// XM_005266071 /// XM_005266072 /// XM_005266073 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008355 // olfactory learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010646 // regulation of cell communication // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0018964 // propylene metabolic process // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021586 // pons maturation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043083 // synaptic cleft // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016595 // glutamate binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 205915_x_at D13515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13515.1 /DEF=Homo sapiens mRNA for key subunit of N-methyl-D-aspartate receptor, complete cds. /FEA=mRNA /PROD=key subunit of N-methyl-D-aspartate receptor /DB_XREF=gi:219919 /UG=Hs.105 glutamate receptor, ionotropic, N-methyl D-aspartate 1 /FL=gb:NM_007327.1 gb:D13515.1 D13515 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRIN1 2902 NM_000832 /// NM_001185090 /// NM_001185091 /// NM_007327 /// NM_021569 /// XM_005266071 /// XM_005266072 /// XM_005266073 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008355 // olfactory learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010646 // regulation of cell communication // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0018964 // propylene metabolic process // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021586 // pons maturation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043083 // synaptic cleft // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016595 // glutamate binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 205916_at NM_002963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002963.2 /DEF=Homo sapiens S100 calcium-binding protein A7 (psoriasin 1) (S100A7), mRNA. /FEA=mRNA /GEN=S100A7 /PROD=S100 calcium-binding protein A7 /DB_XREF=gi:9845518 /UG=Hs.112408 S100 calcium-binding protein A7 (psoriasin 1) /FL=gb:M86757.1 gb:NM_002963.2 NM_002963 S100 calcium binding protein A7 S100A7 6278 NM_002963 /// XM_005245431 0000302 // response to reactive oxygen species // inferred from direct assay /// 0001525 // angiogenesis // non-traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0045087 // innate immune response // non-traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0051238 // sequestering of metal ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071624 // positive regulation of granulocyte chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005925 // focal adhesion // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred by curator /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 205917_at NM_003417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003417.1 /DEF=Homo sapiens zinc finger protein 264 (ZNF264), mRNA. /FEA=mRNA /GEN=ZNF264 /PROD=zinc finger protein 264 /DB_XREF=gi:4585642 /UG=Hs.117077 zinc finger protein 264 /FL=gb:NM_003417.1 NM_003417 zinc finger protein 264 ZNF264 9422 NM_003417 /// XM_005259430 /// XM_006723507 /// XR_243970 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205918_at NM_005070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005070.1 /DEF=Homo sapiens solute carrier family 4, anion exchanger, member 3 (SLC4A3), mRNA. /FEA=mRNA /GEN=SLC4A3 /PROD=solute carrier family 4, anion exchanger, member3 /DB_XREF=gi:4827015 /UG=Hs.1176 solute carrier family 4, anion exchanger, member 3 /FL=gb:L27213.1 gb:U05596.1 gb:NM_005070.1 NM_005070 solute carrier family 4 (anion exchanger), member 3 SLC4A3 6508 NM_005070 /// NM_201574 /// NR_048551 /// XM_005246789 /// XM_005246790 /// XM_006712703 /// XM_006712704 /// XM_006712705 /// XM_006712706 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0051453 // regulation of intracellular pH // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 205919_at NM_005330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005330.2 /DEF=Homo sapiens hemoglobin, epsilon 1 (HBE1), mRNA. /FEA=mRNA /GEN=HBE1 /PROD=hemoglobin, epsilon 1 /DB_XREF=gi:6715605 /UG=Hs.117848 hemoglobin, epsilon 1 /FL=gb:NM_005330.2 NM_005330 hemoglobin, epsilon 1 HBE1 3046 NM_005330 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031721 // hemoglobin alpha binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205920_at NM_003043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003043.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, taurine), member 6 (SLC6A6), mRNA. /FEA=mRNA /GEN=SLC6A6 /PROD=solute carrier family 6 (neurotransmittertransporter, taurine), member 6 /DB_XREF=gi:4507044 /UG=Hs.1194 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 /FL=gb:NM_003043.1 gb:U16120.1 gb:U09220.1 NM_003043 solute carrier family 6 (neurotransmitter transporter), member 6 SLC6A6 6533 NM_001134367 /// NM_001134368 /// NM_003043 /// NR_103507 /// XM_006713307 /// XR_427286 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0015734 // taurine transport // inferred from electronic annotation /// 0015849 // organic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005368 // taurine transmembrane transporter activity // inferred from electronic annotation /// 0005369 // taurine:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0030977 // taurine binding // inferred from electronic annotation 205921_s_at U16120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16120.1 /DEF=Human placental taurine transporter mRNA, complete cds. /FEA=mRNA /PROD=placental taurine transporter /DB_XREF=gi:559852 /UG=Hs.1194 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 /FL=gb:NM_003043.1 gb:U16120.1 gb:U09220.1 U16120 solute carrier family 6 (neurotransmitter transporter), member 6 SLC6A6 6533 NM_001134367 /// NM_001134368 /// NM_003043 /// NR_103507 /// XM_006713307 /// XR_427286 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0015734 // taurine transport // inferred from electronic annotation /// 0015849 // organic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005368 // taurine transmembrane transporter activity // inferred from electronic annotation /// 0005369 // taurine:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0030977 // taurine binding // inferred from electronic annotation 205922_at NM_004665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004665.1 /DEF=Homo sapiens vanin 2 (VNN2), mRNA. /FEA=mRNA /GEN=VNN2 /PROD=vanin 2 /DB_XREF=gi:4759313 /UG=Hs.121102 vanin 2 /FL=gb:NM_004665.1 gb:D89974.1 NM_004665 vanin 2 VNN2 8875 NM_001242350 /// NM_004665 /// NM_078488 /// NR_034173 /// NR_034174 /// NR_110143 /// NR_110144 /// NR_110145 /// NR_110146 /// XM_006715593 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0015939 // pantothenate metabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0017159 // pantetheine hydrolase activity // inferred from direct assay 205923_at NM_005045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005045.1 /DEF=Homo sapiens reelin (RELN), mRNA. /FEA=mRNA /GEN=RELN /PROD=reelin /DB_XREF=gi:4826977 /UG=Hs.12246 reelin /FL=gb:U79716.1 gb:NM_005045.1 NM_005045 reelin RELN 5649 NM_005045 /// NM_173054 0000904 // cell morphogenesis involved in differentiation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0021511 // spinal cord patterning // inferred from sequence or structural similarity /// 0021517 // ventral spinal cord development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021800 // cerebral cortex tangential migration // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0038026 // reelin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from sequence or structural similarity /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from sequence or structural similarity /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from electronic annotation /// 0097119 // postsynaptic density protein 95 clustering // inferred from electronic annotation /// 0097120 // receptor localization to synapse // inferred from electronic annotation /// 0097477 // lateral motor column neuron migration // inferred from electronic annotation /// 1900273 // positive regulation of long-term synaptic potentiation // inferred from sequence or structural similarity /// 1902078 // positive regulation of lateral motor column neuron migration // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000969 // positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070325 // lipoprotein particle receptor binding // inferred from sequence or structural similarity /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from sequence or structural similarity 205924_at BC005035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005035.1 /DEF=Homo sapiens, RAB3B, member RAS oncogene family, clone MGC:12720, mRNA, complete cds. /FEA=mRNA /PROD=RAB3B, member RAS oncogene family /DB_XREF=gi:13477154 /UG=Hs.123072 RAB3B, member RAS oncogene family /FL=gb:BC005035.1 gb:NM_002867.1 gb:M28214.1 BC005035 RAB3B, member RAS oncogene family RAB3B 5865 NM_002867 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0097494 // regulation of vesicle size // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 205925_s_at NM_002867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002867.1 /DEF=Homo sapiens RAB3B, member RAS oncogene family (RAB3B), mRNA. /FEA=mRNA /GEN=RAB3B /PROD=RAB3B, member RAS oncogene family /DB_XREF=gi:4506368 /UG=Hs.123072 RAB3B, member RAS oncogene family /FL=gb:BC005035.1 gb:NM_002867.1 gb:M28214.1 NM_002867 RAB3B, member RAS oncogene family RAB3B 5865 NM_002867 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0097494 // regulation of vesicle size // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 205926_at NM_004843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004843.1 /DEF=Homo sapiens class I cytokine receptor (WSX-1), mRNA. /FEA=mRNA /GEN=WSX-1 /PROD=class I cytokine receptor /DB_XREF=gi:4759327 /UG=Hs.132781 class I cytokine receptor /FL=gb:AF106912.1 gb:AF265242.1 gb:AF053004.1 gb:NM_004843.1 NM_004843 interleukin 27 receptor, alpha IL27RA 9466 NM_004843 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0048302 // regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0070106 // interleukin-27-mediated signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045509 // interleukin-27 receptor activity // inferred from electronic annotation 205927_s_at NM_001910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001910.1 /DEF=Homo sapiens cathepsin E (CTSE), mRNA. /FEA=mRNA /GEN=CTSE /PROD=cathepsin E /DB_XREF=gi:4503144 /UG=Hs.1355 cathepsin E /FL=gb:J05036.1 gb:NM_001910.1 NM_001910 cathepsin E CTSE 1510 NM_001910 /// NM_148964 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from direct assay 0005768 // endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205928_at NM_005815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005815.1 /DEF=Homo sapiens Kruppel-type zinc finger (C2H2) (ZK1), mRNA. /FEA=mRNA /GEN=ZK1 /PROD=Kruppel-type zinc finger (C2H2) /DB_XREF=gi:5032238 /UG=Hs.142150 Kruppel-type zinc finger (C2H2) /FL=gb:AB011414.1 gb:NM_005815.1 NM_005815 zinc finger protein 443 ZNF443 10224 NM_005815 /// XM_005259705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205929_at NM_005814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005814.1 /DEF=Homo sapiens glycoprotein A33 (transmembrane) (GPA33), mRNA. /FEA=mRNA /GEN=GPA33 /PROD=transmembrane glycoprotein A33 precursor /DB_XREF=gi:5031560 /UG=Hs.143131 glycoprotein A33 (transmembrane) /FL=gb:U79725.1 gb:NM_005814.1 NM_005814 glycoprotein A33 (transmembrane) GPA33 10223 NM_005814 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 205930_at NM_005513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005513.1 /DEF=Homo sapiens general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD) (GTF2E1), mRNA. /FEA=mRNA /GEN=GTF2E1 /PROD=general transcription factor IIE, polypeptide 1(alpha subunit, 56kD) /DB_XREF=gi:5031726 /UG=Hs.145381 general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD) /FL=gb:NM_005513.1 NM_005513 general transcription factor IIE, polypeptide 1, alpha 56kDa GTF2E1 2960 NM_005513 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205931_s_at NM_004904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004904.1 /DEF=Homo sapiens cAMP response element-binding protein CRE-BPa (H_GS165L15.1), mRNA. /FEA=mRNA /GEN=H_GS165L15.1 /PROD=cAMP response element-binding protein CRE-BPa /DB_XREF=gi:4758499 /UG=Hs.149 cAMP response element-binding protein CRE-BPa /FL=gb:L05911.1 gb:NM_004904.1 NM_004904 cAMP responsive element binding protein 5 /// uncharacterized LOC401317 CREB5 /// LOC401317 9586 /// 401317 NM_001011666 /// NM_004904 /// NM_182898 /// NM_182899 /// XM_005249906 /// XR_110663 /// XR_112997 /// XR_171648 /// XR_242178 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205932_s_at NM_002448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002448.1 /DEF=Homo sapiens msh (Drosophila) homeo box homolog 1 (formerly homeo box 7) (MSX1), mRNA. /FEA=mRNA /GEN=MSX1 /PROD=msh homeo box homolog 1 /DB_XREF=gi:4505266 /UG=Hs.1494 msh (Drosophila) homeo box homolog 1 (formerly homeo box 7) /FL=gb:M97676.1 gb:NM_002448.1 NM_002448 msh homeobox 1 MSX1 4487 NM_002448 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010463 // mesenchymal cell proliferation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035880 // embryonic nail plate morphogenesis // inferred from mutant phenotype /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042481 // regulation of odontogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0061312 // BMP signaling pathway involved in heart development // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from electronic annotation /// 0090427 // activation of meiosis // inferred from electronic annotation /// 1902255 // positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation /// 2001055 // positive regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205933_at NM_015559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015559.1 /DEF=Homo sapiens KIAA0437 protein (KIAA0437), mRNA. /FEA=mRNA /GEN=KIAA0437 /PROD=KIAA0437 protein /DB_XREF=gi:7662121 /UG=Hs.151717 KIAA0437 protein /FL=gb:AB022660.1 gb:NM_015559.1 NM_015559 SET binding protein 1 SETBP1 26040 NM_001130110 /// NM_015559 /// XM_005258243 /// XM_005258244 /// XM_006722438 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 205934_at NM_006226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006226.1 /DEF=Homo sapiens phospholipase C, epsilon (PLCE), mRNA. /FEA=mRNA /GEN=PLCE /PROD=phospholipase C, epsilon /DB_XREF=gi:5453911 /UG=Hs.153322 phospholipase C, epsilon /FL=gb:NM_006226.1 gb:D42108.1 NM_006226 phospholipase C-like 1 PLCL1 5334 NM_006226 /// XM_005246643 /// XM_005246644 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from electronic annotation 205935_at NM_001451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001451.1 /DEF=Homo sapiens forkhead box F1 (FOXF1), mRNA. /FEA=mRNA /GEN=FOXF1 /PROD=forkhead box F1 /DB_XREF=gi:4503732 /UG=Hs.155591 forkhead box F1 /FL=gb:U13219.1 gb:NM_001451.1 NM_001451 forkhead box F1 FOXF1 2294 NM_001451 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from mutant phenotype /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from mutant phenotype /// 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007494 // midgut development // inferred from mutant phenotype /// 0007498 // mesoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0014822 // detection of wounding // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031016 // pancreas development // inferred from mutant phenotype /// 0043305 // negative regulation of mast cell degranulation // inferred from electronic annotation /// 0045198 // establishment of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048371 // lateral mesodermal cell differentiation // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048613 // embryonic ectodermal digestive tract morphogenesis // inferred from mutant phenotype /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from mutant phenotype /// 0060438 // trachea development // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060446 // branching involved in open tracheal system development // inferred from mutant phenotype /// 0060461 // right lung morphogenesis // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060841 // venous blood vessel development // inferred from mutant phenotype /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0072001 // renal system development // inferred from mutant phenotype /// 0072189 // ureter development // inferred from mutant phenotype /// 0090131 // mesenchyme migration // inferred from electronic annotation /// 0097070 // ductus arteriosus closure // inferred from mutant phenotype 0005634 // nucleus // inferred by curator /// 0005667 // transcription factor complex // not recorded 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 205936_s_at NM_002115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002115.1 /DEF=Homo sapiens hexokinase 3 (white cell) (HK3), mRNA. /FEA=mRNA /GEN=HK3 /PROD=hexokinase 3 (white cell) /DB_XREF=gi:4504394 /UG=Hs.159237 hexokinase 3 (white cell) /FL=gb:U51333.1 gb:NM_002115.1 NM_002115 hexokinase 3 (white cell) HK3 3101 NM_002115 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation 205937_at NM_006569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006569.1 /DEF=Homo sapiens cell growth regulatory with EF-hand domain (CGR11), mRNA. /FEA=mRNA /GEN=CGR11 /PROD=cell growth regulatory with EF-hand domain /DB_XREF=gi:5729762 /UG=Hs.159525 cell growth regulatory with EF-hand domain /FL=gb:U66468.1 gb:NM_006569.1 NM_006569 cell growth regulator with EF-hand domain 1 CGREF1 10669 NM_001166239 /// NM_001166240 /// NM_001166241 /// NM_006569 0006950 // response to stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205938_at NM_014906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014906.1 /DEF=Homo sapiens KIAA1072 protein (KIAA1072), mRNA. /FEA=mRNA /GEN=KIAA1072 /PROD=KIAA1072 protein /DB_XREF=gi:7662471 /UG=Hs.166351 KIAA1072 protein /FL=gb:AB028995.1 gb:NM_014906.1 NM_014906 protein phosphatase, Mg2+/Mn2+ dependent, 1E PPM1E 22843 NM_014906 /// NR_048561 /// XM_005257169 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205939_at NM_000765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000765.2 /DEF=Homo sapiens cytochrome P450, subfamily IIIA, polypeptide 7 (CYP3A7), mRNA. /FEA=mRNA /GEN=CYP3A7 /PROD=cytochrome P450, subfamily IIIA, polypeptide 7 /DB_XREF=gi:13386504 /UG=Hs.172323 cytochrome P450, subfamily IIIA, polypeptide 7 /FL=gb:NM_000765.2 gb:D00408.1 NM_000765 cytochrome P450, family 3, subfamily A, polypeptide 7 /// CYP3A7-CYP3AP1 readthrough CYP3A7 /// CYP3A7-CYP3AP1 1551 /// 100861540 NM_000765 /// NM_001256497 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 205940_at NM_002470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002470.1 /DEF=Homo sapiens myosin, heavy polypeptide 3, skeletal muscle, embryonic (MYH3), mRNA. /FEA=mRNA /GEN=MYH3 /PROD=myosin, heavy polypeptide 3, skeletal muscle,embryonic /DB_XREF=gi:11342671 /UG=Hs.173084 myosin, heavy polypeptide 3, skeletal muscle, embryonic /FL=gb:NM_002470.1 NM_002470 myosin, heavy chain 3, skeletal muscle, embryonic MYH3 4621 NM_002470 /// XM_006721528 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0007517 // muscle organ development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred by curator /// 0045214 // sarcomere organization // non-traceable author statement /// 0060325 // face morphogenesis // inferred by curator 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // non-traceable author statement /// 0032982 // myosin filament // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0051015 // actin filament binding // inferred from mutant phenotype 205941_s_at AI376003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI376003 /FEA=EST /DB_XREF=gi:4175993 /DB_XREF=est:tc30d11.x1 /CLONE=IMAGE:2066133 /UG=Hs.179729 collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia) /FL=gb:NM_000493.1 AI376003 collagen, type X, alpha 1 COL10A1 1300 NM_000493 /// XM_006715332 /// XM_006715333 0001501 // skeletal system development // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205942_s_at NM_005622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005622.1 /DEF=Homo sapiens SA (rat hypertension-associated) homolog (SAH), mRNA. /FEA=mRNA /GEN=SAH /PROD=SA (rat hypertension-associated) homolog /DB_XREF=gi:5032064 /UG=Hs.181345 SA (rat hypertension-associated) homolog /FL=gb:BC002790.1 gb:NM_005622.1 NM_005622 acyl-CoA synthetase medium-chain family member 3 ACSM3 6296 NM_005622 /// NM_202000 /// XM_005255466 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0042632 // cholesterol homeostasis // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015645 // fatty acid ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 205943_at NM_005651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005651.1 /DEF=Homo sapiens tryptophan 2,3-dioxygenase (TDO2), mRNA. /FEA=mRNA /GEN=TDO2 /PROD=tryptophan 2,3-dioxygenase /DB_XREF=gi:5032164 /UG=Hs.183671 tryptophan 2,3-dioxygenase /FL=gb:BC005355.1 gb:NM_005651.1 gb:U32989.1 NM_005651 tryptophan 2,3-dioxygenase TDO2 6999 NM_005651 0006568 // tryptophan metabolic process // inferred from electronic annotation /// 0006569 // tryptophan catabolic process // traceable author statement /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // not recorded /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004833 // tryptophan 2,3-dioxygenase activity // not recorded /// 0004833 // tryptophan 2,3-dioxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 205944_s_at NM_007098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007098.1 /DEF=Homo sapiens clathrin, heavy polypeptide-like 1 (CLTCL1), transcript variant 2, mRNA. /FEA=mRNA /GEN=CLTCL1 /PROD=clathrin, heavy polypeptide-like 1 isoform b /DB_XREF=gi:9257201 /UG=Hs.184916 clathrin, heavy polypeptide-like 1 /FL=gb:U41763.1 gb:U60802.1 gb:NM_007098.1 NM_007098 clathrin, heavy chain-like 1 CLTCL1 8218 NM_001835 /// NM_007098 /// XM_005261281 /// XM_005277800 /// XM_005277801 /// XM_006724326 /// XM_006724327 /// XM_006724328 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype 0005802 // trans-Golgi network // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030135 // coated vesicle // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205945_at NM_000565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000565.1 /DEF=Homo sapiens interleukin 6 receptor (IL6R), mRNA. /FEA=mRNA /GEN=IL6R /PROD=interleukin 6 receptor /DB_XREF=gi:4504672 /UG=Hs.193400 interleukin 6 receptor /FL=gb:NM_000565.1 NM_000565 interleukin 6 receptor IL6R 3570 NM_000565 /// NM_001206866 /// NM_181359 /// XM_005245139 /// XM_005245140 /// XM_006711298 /// XM_006711299 0002384 // hepatic immune response // traceable author statement /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0002690 // positive regulation of leukocyte chemotaxis // traceable author statement /// 0006953 // acute-phase response // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010536 // positive regulation of activation of Janus kinase activity // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0031018 // endocrine pancreas development // inferred by curator /// 0031018 // endocrine pancreas development // inferred from mutant phenotype /// 0032717 // negative regulation of interleukin-8 production // inferred from expression pattern /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032966 // negative regulation of collagen biosynthetic process // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from expression pattern /// 0050830 // defense response to Gram-positive bacterium // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from mutant phenotype /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0070119 // ciliary neurotrophic factor binding // inferred from physical interaction 205946_at X95097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95097.2 /DEF=Homo sapiens mRNA for VIP receptor 2. /FEA=mRNA /GEN=VIP2r /PROD=VIP2 receptor /DB_XREF=gi:4837717 /UG=Hs.2126 vasoactive intestinal peptide receptor 2 /FL=gb:NM_003382.1 gb:L36566.1 X95097 vasoactive intestinal peptide receptor 2 VIPR2 7434 NM_003382 /// XM_005249561 /// XM_006716107 /// XM_006716108 /// XR_242047 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004999 // vasoactive intestinal polypeptide receptor activity // inferred from electronic annotation 205947_s_at NM_003382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003382.1 /DEF=Homo sapiens vasoactive intestinal peptide receptor 2 (VIPR2), mRNA. /FEA=mRNA /GEN=VIPR2 /PROD=vasoactive intestinal peptide receptor 2 /DB_XREF=gi:4507898 /UG=Hs.2126 vasoactive intestinal peptide receptor 2 /FL=gb:NM_003382.1 gb:L36566.1 NM_003382 vasoactive intestinal peptide receptor 2 VIPR2 7434 NM_003382 /// XM_005249561 /// XM_006716107 /// XM_006716108 /// XR_242047 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004999 // vasoactive intestinal polypeptide receptor activity // inferred from electronic annotation 205948_at NM_007050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007050.2 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, T (PTPRT), mRNA. /FEA=mRNA /GEN=PTPRT /PROD=protein tyrosine phosphatase, receptor type, T /DB_XREF=gi:7427522 /UG=Hs.225952 protein tyrosine phosphatase, receptor type, T /FL=gb:AF043644.4 gb:NM_007050.2 NM_007050 protein tyrosine phosphatase, receptor type, T PTPRT 11122 NM_007050 /// NM_133170 /// XM_006723685 /// XM_006723686 /// XM_006723687 /// XM_006723688 /// XM_006723689 0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation /// 0070097 // delta-catenin binding // inferred from physical interaction 205949_at M33987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33987.1 /DEF=Human carbonic anhydrase I (CAI) mRNA, complete cds. /FEA=mRNA /GEN=CA1 /DB_XREF=gi:179792 /UG=Hs.23118 carbonic anhydrase I /FL=gb:M33987.1 gb:NM_001738.1 M33987 carbonic anhydrase I CA1 759 NM_001128829 /// NM_001128830 /// NM_001128831 /// NM_001164830 /// NM_001291967 /// NM_001291968 /// NM_001738 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205950_s_at NM_001738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001738.1 /DEF=Homo sapiens carbonic anhydrase I (CA1), mRNA. /FEA=mRNA /GEN=CA1 /PROD=carbonic anhydrase I /DB_XREF=gi:4502516 /UG=Hs.23118 carbonic anhydrase I /FL=gb:M33987.1 gb:NM_001738.1 NM_001738 carbonic anhydrase I CA1 759 NM_001128829 /// NM_001128830 /// NM_001128831 /// NM_001164830 /// NM_001291967 /// NM_001291968 /// NM_001738 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205951_at NM_005963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005963.2 /DEF=Homo sapiens myosin, heavy polypeptide 1, skeletal muscle, adult (MYH1), mRNA. /FEA=mRNA /GEN=MYH1 /PROD=myosin, heavy polypeptide 1, skeletal muscle,adult /DB_XREF=gi:7669505 /UG=Hs.231581 myosin, heavy polypeptide 1, skeletal muscle, adult /FL=gb:AF111785.1 gb:NM_005963.2 NM_005963 myosin, heavy chain 1, skeletal muscle, adult MYH1 4619 NM_005963 0006936 // muscle contraction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005859 // muscle myosin complex // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 205952_at NM_002246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002246.1 /DEF=Homo sapiens potassium channel, subfamily K, member 3 (TASK) (KCNK3), mRNA. /FEA=mRNA /GEN=KCNK3 /PROD=potassium channel, subfamily K, member 3 (TASK) /DB_XREF=gi:4504848 /UG=Hs.24040 potassium channel, subfamily K, member 3 (TASK-1) /FL=gb:AF065163.1 gb:AF006823.1 gb:NM_002246.1 NM_002246 potassium channel, subfamily K, member 3 KCNK3 3777 NM_002246 /// XM_005264293 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0071294 // cellular response to zinc ion // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from mutant phenotype /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005252 // open rectifier potassium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0022841 // potassium ion leak channel activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205953_at NM_014813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014813.1 /DEF=Homo sapiens KIAA0806 gene product (KIAA0806), mRNA. /FEA=mRNA /GEN=KIAA0806 /PROD=KIAA0806 gene product /DB_XREF=gi:7662319 /UG=Hs.24279 KIAA0806 gene product /FL=gb:AB018349.1 gb:NM_014813.1 NM_014813 leucine-rich repeats and immunoglobulin-like domains 2 LRIG2 9860 NM_014813 /// XM_005271369 /// XM_006711072 /// XM_006711073 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205954_at NM_006917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006917.1 /DEF=Homo sapiens retinoid X receptor, gamma (RXRG), mRNA. /FEA=mRNA /GEN=RXRG /PROD=retinoid X receptor, gamma /DB_XREF=gi:5902067 /UG=Hs.26550 retinoid X receptor, gamma /FL=gb:U38480.1 gb:NM_006917.1 NM_006917 retinoid X receptor, gamma RXRG 6258 NM_001256570 /// NM_001256571 /// NM_006917 /// NR_033824 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205955_at NM_018336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018336.1 /DEF=Homo sapiens hypothetical protein FLJ11136 (FLJ11136), mRNA. /FEA=mRNA /GEN=FLJ11136 /PROD=hypothetical protein FLJ11136 /DB_XREF=gi:8922891 /UG=Hs.274324 hypothetical protein FLJ11136 /FL=gb:NM_018336.1 NM_018336 205956_x_at NM_013290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013290.1 /DEF=Homo sapiens GT198, complete ORF (HUMGT198A), mRNA. /FEA=mRNA /GEN=HUMGT198A /PROD=GT198, complete ORF /DB_XREF=gi:7019422 /UG=Hs.279032 GT198, complete ORF /FL=gb:NM_013290.1 gb:AB030304.1 gb:NM_016556.1 NM_013290 PSMC3 interacting protein PSMC3IP 29893 NM_001256014 /// NM_001256015 /// NM_001256016 /// NM_013290 /// NM_016556 /// NR_045669 /// NR_045670 /// NR_045671 0006310 // DNA recombination // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype 205957_at NM_005393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005393.1 /DEF=Homo sapiens plexin B3 (PLXNB3), mRNA. /FEA=mRNA /GEN=PLXNB3 /PROD=plexin B3 /DB_XREF=gi:10864080 /UG=Hs.283711 plexin B3 /FL=gb:NM_005393.1 gb:AF149019.1 NM_005393 plexin B3 PLXNB3 5365 NM_001163257 /// NM_005393 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0010593 // negative regulation of lamellipodium assembly // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034260 // negative regulation of GTPase activity // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060537 // muscle tissue development // inferred from sequence or structural similarity /// 0060537 // muscle tissue development // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 205958_x_at NM_022579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022579.1 /DEF=Homo sapiens chorionic somatomammotropin hormone-like 1 (CSHL1), transcript variant 3, mRNA. /FEA=mRNA /GEN=CSHL1 /PROD=chorionic somatomammotropin hormone-like 1,isoform 3 precursor /DB_XREF=gi:12545375 /UG=Hs.287269 chorionic somatomammotropin hormone-like 1 /FL=gb:NM_022579.1 NM_022579 chorionic somatomammotropin hormone-like 1 CSHL1 1444 NM_001318 /// NM_022579 /// NM_022580 /// NM_022581 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 205959_at NM_002427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002427.2 /DEF=Homo sapiens matrix metalloproteinase 13 (collagenase 3) (MMP13), mRNA. /FEA=mRNA /GEN=MMP13 /PROD=matrix metalloproteinase 13 preproprotein /DB_XREF=gi:13027796 /UG=Hs.2936 matrix metalloproteinase 13 (collagenase 3) /FL=gb:NM_002427.2 NM_002427 matrix metallopeptidase 13 (collagenase 3) MMP13 4322 NM_002427 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205960_at NM_002612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002612.1 /DEF=Homo sapiens pyruvate dehydrogenase kinase, isoenzyme 4 (PDK4), mRNA. /FEA=mRNA /GEN=PDK4 /PROD=pyruvate dehydrogenase kinase, isoenzyme 4 /DB_XREF=gi:4505692 /UG=Hs.299221 pyruvate dehydrogenase kinase, isoenzyme 4 /FL=gb:U54617.1 gb:NM_002612.1 NM_002612 pyruvate dehydrogenase kinase, isozyme 4 PDK4 5166 NM_002612 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0009267 // cellular response to starvation // inferred from direct assay /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from mutant phenotype /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010565 // regulation of cellular ketone metabolic process // inferred from sequence or structural similarity /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042304 // regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045124 // regulation of bone resorption // inferred from electronic annotation /// 0046320 // regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0071398 // cellular response to fatty acid // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 205961_s_at NM_004682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004682.1 /DEF=Homo sapiens PC4 and SFRS1 interacting protein 2 (PSIP2), mRNA. /FEA=mRNA /GEN=PSIP2 /PROD=PC4 and SFRS1 interacting protein 2 /DB_XREF=gi:4758869 /UG=Hs.306179 PC4 and SFRS1 interacting protein 2 /FL=gb:AF098483.1 gb:NM_004682.1 NM_004682 PC4 and SFRS1 interacting protein 1 PSIP1 11168 NM_001128217 /// NM_021144 /// NM_033222 /// XM_005251355 /// XM_005251356 /// XM_005251357 /// XM_005251358 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034399 // nuclear periphery // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from sequence or structural similarity 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097100 // supercoiled DNA binding // inferred from sequence or structural similarity 205962_at NM_002577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002577.1 /DEF=Homo sapiens p21 (CDKN1A)-activated kinase 2 (PAK2), mRNA. /FEA=mRNA /GEN=PAK2 /PROD=p21 (CDKN1A)-activated kinase 2 /DB_XREF=gi:4505598 /UG=Hs.30692 p21 (CDKN1A)-activated kinase 2 /FL=gb:NM_002577.1 gb:U24153.1 NM_002577 p21 protein (Cdc42/Rac)-activated kinase 2 PAK2 5062 NM_002577 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 205963_s_at NM_005147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005147.1 /DEF=Homo sapiens tumorous imaginal discs (Drosophila) homolog (TID1), mRNA. /FEA=mRNA /GEN=TID1 /PROD=tumorous imaginal discs (Drosophila) homolog /DB_XREF=gi:4827025 /UG=Hs.311057 DnaJ (Hsp40) homolog, subfamily A, member 3 /FL=gb:AF061749.1 gb:NM_005147.1 NM_005147 DnaJ (Hsp40) homolog, subfamily A, member 3 DNAJA3 9093 NM_001135110 /// NM_001286516 /// NM_005147 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from direct assay /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009408 // response to heat // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // inferred from mutant phenotype /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0033256 // I-kappaB/NF-kappaB complex // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005133 // interferon-gamma receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 205964_at NM_024106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024106.1 /DEF=Homo sapiens hypothetical protein MGC2663 (MGC2663), mRNA. /FEA=mRNA /GEN=MGC2663 /PROD=hypothetical protein MGC2663 /DB_XREF=gi:13129115 /UG=Hs.324700 hypothetical protein MGC2663 /FL=gb:BC001791.1 gb:NM_024106.1 NM_024106 zinc finger protein 426 ZNF426 79088 NM_024106 /// XM_005260076 /// XM_005260077 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205965_at NM_006399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006399.1 /DEF=Homo sapiens basic leucine zipper transcription factor, ATF-like (BATF), mRNA. /FEA=mRNA /GEN=BATF /PROD=basic leucine zipper transcription factor,ATF-like /DB_XREF=gi:5453562 /UG=Hs.41691 basic leucine zipper transcription factor, ATF-like /FL=gb:U15460.1 gb:D42106.1 gb:NM_006399.1 NM_006399 basic leucine zipper transcription factor, ATF-like BATF 10538 NM_006399 0001816 // cytokine production // inferred from sequence or structural similarity /// 0002320 // lymphoid progenitor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0045064 // T-helper 2 cell differentiation // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0060218 // hematopoietic stem cell differentiation // inferred from sequence or structural similarity /// 0072539 // T-helper 17 cell differentiation // inferred from sequence or structural similarity /// 0072540 // T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 205966_at NM_005645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005645.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, K, 18kD (TAF2K), mRNA. /FEA=mRNA /GEN=TAF2K /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, K, 18kD /DB_XREF=gi:5032154 /UG=Hs.42911 TATA box binding protein (TBP)-associated factor, RNA polymerase II, K, 18kD /FL=gb:NM_005645.1 NM_005645 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa TAF13 6884 NM_005645 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005669 // transcription factor TFIID complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205967_at NM_003542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003542.2 /DEF=Homo sapiens H4 histone family, member G (H4FG), mRNA. /FEA=mRNA /GEN=H4FG /PROD=H4 histone family, member G /DB_XREF=gi:5579465 /UG=Hs.46423 H4 histone family, member G /FL=gb:NM_003542.2 NM_003542 histone cluster 1, H4a /// histone cluster 1, H4b /// histone cluster 1, H4c /// histone cluster 1, H4d /// histone cluster 1, H4e /// histone cluster 1, H4f /// histone cluster 1, H4h /// histone cluster 1, H4i /// histone cluster 1, H4j /// histone cluster 1, H4k /// histone cluster 1, H4l /// histone cluster 2, H4a /// histone cluster 2, H4b /// histone cluster 4, H4 HIST1H4A /// HIST1H4B /// HIST1H4C /// HIST1H4D /// HIST1H4E /// HIST1H4F /// HIST1H4H /// HIST1H4I /// HIST1H4J /// HIST1H4K /// HIST1H4L /// HIST2H4A /// HIST2H4B /// HIST4H4 8294 /// 8359 /// 8360 /// 8361 /// 8362 /// 8363 /// 8364 /// 8365 /// 8366 /// 8367 /// 8368 /// 8370 /// 121504 /// 554313 NM_001034077 /// NM_003495 /// NM_003538 /// NM_003539 /// NM_003540 /// NM_003541 /// NM_003542 /// NM_003543 /// NM_003544 /// NM_003545 /// NM_003546 /// NM_003548 /// NM_021968 /// NM_175054 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 205968_at NM_002252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002252.1 /DEF=Homo sapiens potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 (KCNS3), mRNA. /FEA=mRNA /GEN=KCNS3 /PROD=potassium voltage-gated channel,delayed-rectifier, subfamily S, member 3 /DB_XREF=gi:4504862 /UG=Hs.47584 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 /FL=gb:BC004148.1 gb:BC004987.1 gb:AF043472.1 gb:NM_002252.1 NM_002252 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 KCNS3 3790 NM_001282428 /// NM_002252 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 205969_at NM_001086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001086.1 /DEF=Homo sapiens arylacetamide deacetylase (esterase) (AADAC), mRNA. /FEA=mRNA /GEN=AADAC /PROD=arylacetamide deacetylase /DB_XREF=gi:4557226 /UG=Hs.587 arylacetamide deacetylase (esterase) /FL=gb:NM_001086.1 gb:L32179.1 NM_001086 arylacetamide deacetylase AADAC 13 NM_001086 /// XM_005247103 /// XM_005247104 0008152 // metabolic process // inferred from electronic annotation /// 0010898 // positive regulation of triglyceride catabolic process // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0016298 // lipase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017171 // serine hydrolase activity // inferred from direct assay /// 0019213 // deacetylase activity // inferred from direct assay /// 0052689 // carboxylic ester hydrolase activity // inferred from electronic annotation 205970_at NM_005954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005954.1 /DEF=Homo sapiens metallothionein 3 (growth inhibitory factor (neurotrophic)) (MT3), mRNA. /FEA=mRNA /GEN=MT3 /PROD=metallothionein 3 (growth inhibitory factor(neurotrophic)) /DB_XREF=gi:5174761 /UG=Hs.73133 metallothionein 3 (growth inhibitory factor (neurotrophic)) /FL=gb:NM_005954.1 NM_005954 metallothionein 3 MT3 4504 NM_005954 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006112 // energy reserve metabolic process // inferred from sequence or structural similarity /// 0006707 // cholesterol catabolic process // inferred from sequence or structural similarity /// 0006829 // zinc ion transport // inferred from sequence or structural similarity /// 0006875 // cellular metal ion homeostasis // non-traceable author statement /// 0006875 // cellular metal ion homeostasis // traceable author statement /// 0006882 // cellular zinc ion homeostasis // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010507 // negative regulation of autophagy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010940 // positive regulation of necrotic cell death // inferred from direct assay /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0010942 // positive regulation of cell death // inferred from sequence or structural similarity /// 0014002 // astrocyte development // inferred from sequence or structural similarity /// 0016570 // histone modification // inferred from mutant phenotype /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // traceable author statement /// 0030517 // negative regulation of axon extension // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032095 // regulation of response to food // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0033210 // leptin-mediated signaling pathway // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0036091 // positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0044242 // cellular lipid catabolic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051354 // negative regulation of oxidoreductase activity // inferred from direct assay /// 0055069 // zinc ion homeostasis // inferred from direct assay /// 0055073 // cadmium ion homeostasis // inferred from direct assay /// 0060049 // regulation of protein glycosylation // inferred from sequence or structural similarity /// 0060547 // negative regulation of necrotic cell death // inferred from direct assay /// 0060547 // negative regulation of necrotic cell death // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071732 // cellular response to nitric oxide // inferred from direct assay /// 0097214 // positive regulation of lysosomal membrane permeability // inferred from sequence or structural similarity /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from direct assay /// 2000376 // positive regulation of oxygen metabolic process // inferred from sequence or structural similarity /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016234 // inclusion body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046870 // cadmium ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205971_s_at NM_001906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001906.1 /DEF=Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA. /FEA=mRNA /GEN=CTRB1 /PROD=chymotrypsinogen B1 /DB_XREF=gi:4503134 /UG=Hs.74502 chymotrypsinogen B1 /FL=gb:BC005385.1 gb:M24400.1 gb:NM_001906.1 NM_001906 chymotrypsinogen B1 /// chymotrypsinogen B2 CTRB1 /// CTRB2 1504 /// 440387 NM_001025200 /// NM_001906 0006508 // proteolysis // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 205972_at NM_006841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006841.1 /DEF=Homo sapiens transporter protein; system N1 Na+ and H+-coupled glutamine transporter (G17), mRNA. /FEA=mRNA /GEN=G17 /PROD=transporter protein; system N1 Na+ andH+-coupled glutamine transporter /DB_XREF=gi:5870892 /UG=Hs.76460 transporter protein; system N1 Na+ and H+-coupled glutamine transporter /FL=gb:AF244548.1 gb:U49082.1 gb:NM_006841.1 NM_006841 solute carrier family 38, member 3 SLC38A3 10991 NM_006841 /// XM_006712954 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006867 // asparagine transport // inferred from direct assay /// 0006868 // glutamine transport // inferred from direct assay /// 0015808 // L-alanine transport // inferred from direct assay /// 0015817 // histidine transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005290 // L-histidine transmembrane transporter activity // inferred from direct assay /// 0015180 // L-alanine transmembrane transporter activity // inferred from direct assay /// 0015182 // L-asparagine transmembrane transporter activity // inferred from direct assay /// 0015186 // L-glutamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 205973_at NM_022549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022549.1 /DEF=Homo sapiens fasciculation and elongation protein zeta 1 (zygin I) (FEZ1), transcript variant 2, mRNA. /FEA=mRNA /GEN=FEZ1 /PROD=zygin 1, isoform 2 /DB_XREF=gi:12025679 /UG=Hs.79226 fasciculation and elongation protein zeta 1 (zygin I) /FL=gb:NM_022549.1 gb:U60062.1 NM_022549 fasciculation and elongation protein zeta 1 (zygin I) FEZ1 9638 NM_005103 /// NM_022549 /// XM_005271734 /// XM_005271735 0006810 // transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051654 // establishment of mitochondrion localization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 205974_at AI168371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI168371 /FEA=EST /DB_XREF=gi:3701541 /DB_XREF=est:qa24h02.s1 /CLONE=IMAGE:1687731 /UG=Hs.83465 homeo box D1 /FL=gb:AF241528.1 gb:NM_024501.1 AI168371 homeobox D1 HOXD1 3231 NM_024501 /// XM_005246507 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205975_s_at NM_024501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024501.1 /DEF=Homo sapiens homeo box D1 (HOXD1), mRNA. /FEA=mRNA /GEN=HOXD1 /PROD=homeo box D1 /DB_XREF=gi:13375631 /UG=Hs.83465 homeo box D1 /FL=gb:AF241528.1 gb:NM_024501.1 NM_024501 homeobox D1 HOXD1 3231 NM_024501 /// XM_005246507 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205976_at NM_014929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014929.1 /DEF=Homo sapiens KIAA0971 protein (KIAA0971), mRNA. /FEA=mRNA /GEN=KIAA0971 /PROD=KIAA0971 protein /DB_XREF=gi:7662421 /UG=Hs.84429 KIAA0971 protein /FL=gb:AB023188.1 gb:NM_014929.1 NM_014929 FAST kinase domains 2 FASTKD2 22868 NM_001136193 /// NM_001136194 /// NM_014929 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 205977_s_at NM_005232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005232.1 /DEF=Homo sapiens EphA1 (EPHA1), mRNA. /FEA=mRNA /GEN=EPHA1 /PROD=EphA1 /DB_XREF=gi:4885208 /UG=Hs.89839 EphA1 /FL=gb:M18391.1 gb:NM_005232.1 NM_005232 EPH receptor A1 EPHA1 2041 NM_005232 /// XM_006715879 /// XM_006715880 /// XR_428169 0001525 // angiogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 205978_at NM_004795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004795.1 /DEF=Homo sapiens klotho (KL), mRNA. /FEA=mRNA /GEN=KL /PROD=klotho /DB_XREF=gi:4758653 /UG=Hs.94592 klotho /FL=gb:AB005142.1 gb:NM_004795.1 NM_004795 klotho KL 9365 NM_004795 /// NM_153683 /// XM_006719895 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004566 // beta-glucuronidase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005499 // vitamin D binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008422 // beta-glucosidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 205979_at NM_002407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002407.1 /DEF=Homo sapiens mammaglobin 2 (MGB2), mRNA. /FEA=mRNA /GEN=MGB2 /PROD=mammaglobin 2 /DB_XREF=gi:4505170 /UG=Hs.97644 mammaglobin 2 /FL=gb:AF071219.1 gb:NM_002407.1 NM_002407 secretoglobin, family 2A, member 1 SCGB2A1 4246 NM_002407 0030521 // androgen receptor signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005497 // androgen binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 205980_s_at NM_015366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015366.1 /DEF=Homo sapiens Rho GTPase activating protein 8 (ARHGAP8), mRNA. /FEA=mRNA /GEN=ARHGAP8 /PROD=Rho GTPase activating protein 8 /DB_XREF=gi:7656903 /UG=Hs.102336 Rho GTPase activating protein 8 /FL=gb:NM_015366.1 NM_015366 Rho GTPase activating protein 8 /// PRR5-ARHGAP8 readthrough ARHGAP8 /// PRR5-ARHGAP8 23779 /// 553158 NM_001017526 /// NM_001198726 /// NM_181334 /// NM_181335 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031932 // TORC2 complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 205981_s_at NM_001564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001564.1 /DEF=Homo sapiens inhibitor of growth family, member 1-like (ING1L), mRNA. /FEA=mRNA /GEN=ING1L /PROD=inhibitor of growth 1-like /DB_XREF=gi:4504694 /UG=Hs.107153 inhibitor of growth family, member 1-like /FL=gb:AB012853.1 gb:NM_001564.1 gb:AF053537.1 NM_001564 inhibitor of growth family, member 2 ING2 3622 NM_001291959 /// NM_001564 /// XM_005262982 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007141 // male meiosis I // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from sequence or structural similarity /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048133 // male germ-line stem cell division // inferred from sequence or structural similarity /// 0072520 // seminiferous tubule development // inferred from sequence or structural similarity /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // traceable author statement /// 2000772 // regulation of cellular senescence // non-traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // non-traceable author statement /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 205982_x_at NM_003018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003018.1 /DEF=Homo sapiens surfactant, pulmonary-associated protein C (SFTPC), mRNA. /FEA=mRNA /GEN=SFTPC /PROD=surfactant, pulmonary-associated protein C /DB_XREF=gi:4506906 /UG=Hs.1074 surfactant, pulmonary-associated protein C /FL=gb:J03553.1 gb:J03517.1 gb:NM_003018.1 NM_003018 surfactant protein C SFTPC 6440 NM_001172357 /// NM_001172410 /// NM_003018 /// XM_005273598 /// XM_006716379 /// XM_006716380 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070741 // response to interleukin-6 // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071732 // cellular response to nitric oxide // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 205983_at NM_004413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004413.1 /DEF=Homo sapiens dipeptidase 1 (renal) (DPEP1), mRNA. /FEA=mRNA /GEN=DPEP1 /PROD=dipeptidase 1 (renal) /DB_XREF=gi:4758189 /UG=Hs.109 dipeptidase 1 (renal) /FL=gb:NM_004413.1 gb:J05257.1 NM_004413 dipeptidase 1 (renal) DPEP1 1800 NM_001128141 /// NM_004413 /// XM_005256285 /// XM_005256286 /// XM_006721159 /// XM_006721160 0006508 // proteolysis // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0016999 // antibiotic metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071732 // cellular response to nitric oxide // inferred from sequence or structural similarity /// 0072340 // cellular lactam catabolic process // traceable author statement 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070573 // metallodipeptidase activity // inferred from direct assay /// 0072341 // modified amino acid binding // inferred from direct assay 205984_at NM_001882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001882.2 /DEF=Homo sapiens corticotropin releasing hormone-binding protein (CRHBP), mRNA. /FEA=mRNA /GEN=CRHBP /PROD=corticotropin releasing hormone-binding protein /DB_XREF=gi:5921997 /UG=Hs.115617 corticotropin releasing hormone-binding protein /FL=gb:NM_001882.2 NM_001882 corticotropin releasing hormone binding protein CRHBP 1393 NM_001882 0001963 // synaptic transmission, dopaminergic // inferred from sequence or structural similarity /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007565 // female pregnancy // inferred from direct assay /// 0007565 // female pregnancy // inferred from expression pattern /// 0007610 // behavior // inferred from sequence or structural similarity /// 0007611 // learning or memory // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0033554 // cellular response to stress // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0035865 // cellular response to potassium ion // inferred from direct assay /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from direct assay /// 0048149 // behavioral response to ethanol // inferred from mutant phenotype /// 0050795 // regulation of behavior // inferred from mutant phenotype /// 0051459 // regulation of corticotropin secretion // inferred from direct assay /// 0051460 // negative regulation of corticotropin secretion // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071314 // cellular response to cocaine // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0097211 // cellular response to gonadotropin-releasing hormone // inferred from sequence or structural similarity /// 1900011 // negative regulation of corticotropin-releasing hormone receptor activity // inferred from direct assay /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005767 // secondary lysosome // inferred from sequence or structural similarity /// 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031045 // dense core granule // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043679 // axon terminus // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0051424 // corticotropin-releasing hormone binding // inferred from direct assay /// 0051424 // corticotropin-releasing hormone binding // inferred from physical interaction 205985_x_at NM_000085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000085.1 /DEF=Homo sapiens chloride channel Kb (CLCNKB), mRNA. /FEA=mRNA /GEN=CLCNKB /PROD=chloride channel Kb /DB_XREF=gi:4557474 /UG=Hs.123059 chloride channel Kb /FL=gb:NM_000085.1 NM_000085 chloride channel, voltage-sensitive Kb CLCNKB 1188 NM_000085 /// NM_001165945 /// XM_005245733 /// XM_006710069 /// XM_006710070 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205986_at NM_004920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004920.1 /DEF=Homo sapiens apoptosis-associated tyrosine kinase (AATK), mRNA. /FEA=mRNA /GEN=AATK /PROD=apoptosis-associated tyrosine kinase /DB_XREF=gi:4758641 /UG=Hs.128316 apoptosis-associated tyrosine kinase /FL=gb:AB014541.1 gb:NM_004920.1 NM_004920 apoptosis-associated tyrosine kinase AATK 9625 NM_001080395 /// NM_004920 /// XM_005257855 /// XM_006722193 /// XM_006722194 /// XM_006722195 /// XM_006722196 /// XM_006722197 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0032482 // Rab protein signal transduction // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 205987_at NM_001765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001765.1 /DEF=Homo sapiens CD1C antigen, c polypeptide (CD1C), mRNA. /FEA=mRNA /GEN=CD1C /PROD=CD1C antigen, c polypeptide /DB_XREF=gi:4502646 /UG=Hs.1311 CD1C antigen, c polypeptide /FL=gb:M28827.1 gb:NM_001765.1 NM_001765 CD1c molecule CD1C 911 NM_001765 /// XM_005245579 0002286 // T cell activation involved in immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030883 // endogenous lipid antigen binding // inferred from direct assay /// 0030884 // exogenous lipid antigen binding // inferred from direct assay /// 0051861 // glycolipid binding // inferred from direct assay /// 0071723 // lipopeptide binding // inferred from direct assay 205988_at NM_003874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003874.1 /DEF=Homo sapiens CD84 antigen (leukocyte antigen) (CD84), mRNA. /FEA=mRNA /GEN=CD84 /PROD=CD84 antigen (leukocyte antigen) /DB_XREF=gi:4502686 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:U82988.1 gb:NM_003874.1 gb:AF054815.1 NM_003874 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205989_s_at NM_002433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002433.1 /DEF=Homo sapiens myelin oligodendrocyte glycoprotein (MOG), mRNA. /FEA=mRNA /GEN=MOG /PROD=myelin oligodendrocyte glycoprotein /DB_XREF=gi:11321598 /UG=Hs.141308 myelin oligodendrocyte glycoprotein /FL=gb:NM_002433.1 gb:U64564.1 gb:U18798.1 NM_002433 myelin oligodendrocyte glycoprotein MOG 4340 NM_001008228 /// NM_001008229 /// NM_001170418 /// NM_002433 /// NM_206809 /// NM_206810 /// NM_206811 /// NM_206812 /// NM_206813 /// NM_206814 /// XM_005249131 /// XM_005249139 /// XM_005249140 /// XM_005272820 /// XM_005272829 /// XM_005272830 /// XM_005274865 /// XM_005274874 /// XM_005274875 /// XM_005274977 /// XM_005274986 /// XM_005275125 /// XM_005275134 /// XM_005275252 /// XM_005275261 /// XM_005275262 /// XM_005275410 /// XM_005275419 /// XM_005275558 /// XM_005275567 /// XM_005275568 0007155 // cell adhesion // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0034126 // positive regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 205990_s_at NM_003392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003392.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 5A (WNT5A), mRNA. /FEA=mRNA /GEN=WNT5A /PROD=wingless-type MMTV integration site family,member 5A /DB_XREF=gi:4507928 /UG=Hs.152213 wingless-type MMTV integration site family, member 5A /FL=gb:L20861.1 gb:NM_003392.1 NM_003392 wingless-type MMTV integration site family, member 5A WNT5A 7474 NM_001256105 /// NM_003392 /// XM_006713324 0000187 // activation of MAPK activity // inferred from direct assay /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from expression pattern /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002741 // positive regulation of cytokine secretion involved in immune response // inferred from mutant phenotype /// 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0003344 // pericardium morphogenesis // inferred from electronic annotation /// 0003401 // axis elongation // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from direct assay /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from mutant phenotype /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0007257 // activation of JUN kinase activity // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007442 // hindgut morphogenesis // inferred from electronic annotation /// 0007494 // midgut development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008595 // anterior/posterior axis specification, embryo // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from expression pattern /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0021891 // olfactory bulb interneuron development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030825 // positive regulation of cGMP metabolic process // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045778 // positive regulation of ossification // inferred from mutant phenotype /// 0045836 // positive regulation of meiosis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048850 // hypophysis morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0050729 // positive regulation of inflammatory response // inferred from mutant phenotype /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060026 // convergent extension // inferred from electronic annotation /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060065 // uterus development // inferred from electronic annotation /// 0060067 // cervix development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060324 // face development // inferred from mutant phenotype /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from direct assay /// 0060599 // lateral sprouting involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060606 // tube closure // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0060760 // positive regulation of response to cytokine stimulus // inferred from direct assay /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from mutant phenotype /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0061347 // planar cell polarity pathway involved in outflow tract morphogenesis // inferred from electronic annotation /// 0061348 // planar cell polarity pathway involved in ventricular septum morphogenesis // inferred from electronic annotation /// 0061349 // planar cell polarity pathway involved in cardiac right atrium morphogenesis // inferred from electronic annotation /// 0061350 // planar cell polarity pathway involved in cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0061354 // planar cell polarity pathway involved in pericardium morphogenesis // inferred from electronic annotation /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0071219 // cellular response to molecule of bacterial origin // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0071277 // cellular response to calcium ion // inferred from expression pattern /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0072201 // negative regulation of mesenchymal cell proliferation // inferred from direct assay /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred from electronic annotation /// 2000484 // positive regulation of interleukin-8 secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005110 // frizzled-2 binding // inferred from electronic annotation /// 0005115 // receptor tyrosine kinase-like orphan receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048018 // receptor agonist activity // inferred by curator 205991_s_at NM_006902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006902.2 /DEF=Homo sapiens paired mesoderm homeo box 1 (PMX1), transcript variant pmx-1a, mRNA. /FEA=mRNA /GEN=PMX1 /PROD=paired mesoderm homeobox 1, isoform pmx-1a /DB_XREF=gi:12707578 /UG=Hs.155606 paired mesoderm homeo box 1 /FL=gb:NM_006902.2 NM_006902 paired related homeobox 1 PRRX1 5396 NM_006902 /// NM_022716 /// XM_006711388 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 205992_s_at NM_000585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000585.1 /DEF=Homo sapiens interleukin 15 (IL15), mRNA. /FEA=mRNA /GEN=IL15 /PROD=interleukin 15 /DB_XREF=gi:10835152 /UG=Hs.168132 interleukin 15 /FL=gb:NM_000585.1 gb:U14407.1 NM_000585 interleukin 15 IL15 3600 NM_000585 /// NM_172174 /// NM_172175 /// NR_037840 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001866 // NK T cell proliferation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0045062 // extrathymic T cell selection // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050691 // regulation of defense response to virus by host // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 205993_s_at NM_005994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005994.1 /DEF=Homo sapiens T-box 2 (TBX2), mRNA. /FEA=mRNA /GEN=TBX2 /PROD=T-box 2 /DB_XREF=gi:5174712 /UG=Hs.168357 T-box 2 /FL=gb:NM_005994.1 gb:U28049.1 NM_005994 T-box 2 TBX2 6909 NM_005994 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048596 // embryonic camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060465 // pharynx development // inferred from sequence or structural similarity /// 0060560 // developmental growth involved in morphogenesis // inferred from electronic annotation /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 1901208 // negative regulation of heart looping // inferred from sequence or structural similarity /// 1901211 // negative regulation of cardiac chamber formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 205994_at NM_001973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001973.1 /DEF=Homo sapiens ELK4, ETS-domain protein (SRF accessory protein 1) (ELK4), transcript variant a, mRNA. /FEA=mRNA /GEN=ELK4 /PROD=ELK4 protein, isoform a /DB_XREF=gi:4503556 /UG=Hs.169241 ELK4, ETS-domain protein (SRF accessory protein 1) /FL=gb:M85165.1 gb:NM_001973.1 NM_001973 ELK4, ETS-domain protein (SRF accessory protein 1) ELK4 2005 NM_001973 /// NM_021795 /// XM_005244950 /// XM_005244951 /// XR_426764 /// XR_426765 /// XR_426766 /// XR_426767 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0070932 // histone H3 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001047 // core promoter binding // traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 205995_x_at NM_014642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014642.1 /DEF=Homo sapiens KIAA0036 gene product (KIAA0036), mRNA. /FEA=mRNA /GEN=KIAA0036 /PROD=KIAA0036 gene product /DB_XREF=gi:7661875 /UG=Hs.169387 KIAA0036 gene product /FL=gb:D25278.1 gb:NM_014642.1 NM_014642 IQ motif containing B1 IQCB1 9657 NM_001023570 /// NM_001023571 /// XM_005247911 /// XM_005247912 /// XM_005247913 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 205996_s_at NM_013411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013411.1 /DEF=Homo sapiens adenylate kinase 2 (AK2), nuclear gene encoding mitochondrial protein, transcript variant AK2B, mRNA. /FEA=mRNA /GEN=AK2 /PROD=adenylate kinase 2 isoform b /DB_XREF=gi:7524345 /UG=Hs.171811 adenylate kinase 2 /FL=gb:U54645.1 gb:NM_013411.1 NM_013411 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 205997_at NM_021778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021778.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 28 (ADAM28), transcript variant 2, mRNA. /FEA=mRNA /GEN=ADAM28 /PROD=a disintegrin and metalloproteinase domain 28,isoform 2 preproprotein /DB_XREF=gi:11496995 /UG=Hs.174030 a disintegrin and metalloproteinase domain 28 /FL=gb:NM_021778.1 gb:AF137334.1 gb:NM_014265.1 NM_021778 ADAM metallopeptidase domain 28 ADAM28 10863 NM_014265 /// NM_021777 /// XM_005273378 /// XM_005273379 /// XM_005273380 /// XM_005273381 /// XM_005273382 /// XM_006716273 /// XM_006716274 /// XM_006716275 /// XR_247120 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 205998_x_at NM_017460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017460.2 /DEF=Homo sapiens cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4), mRNA. /FEA=mRNA /GEN=CYP3A4 /PROD=cytochrome P450, subfamily IIIA, polypeptide 4 /DB_XREF=gi:13435385 /UG=Hs.178738 cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 /FL=gb:NM_017460.2 gb:M18907.1 gb:AF182273.1 NM_017460 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A4 1576 NM_001202855 /// NM_001202856 /// NM_001202857 /// NM_017460 0006629 // lipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0008209 // androgen metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0036378 // calcitriol biosynthetic process from calciol // inferred from direct assay /// 0042359 // vitamin D metabolic process // inferred by curator /// 0042737 // drug catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005496 // steroid binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from direct assay /// 0033780 // taurochenodeoxycholate 6alpha-hydroxylase activity // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047638 // albendazole monooxygenase activity // inferred from electronic annotation /// 0050591 // quinine 3-monooxygenase activity // inferred from electronic annotation /// 0050649 // testosterone 6-beta-hydroxylase activity // inferred from mutant phenotype /// 0070576 // vitamin D 24-hydroxylase activity // inferred from direct assay 205999_x_at AF182273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182273.1 /DEF=Homo sapiens cytochrome P450-3A4 (CYP3A4) mRNA, complete cds. /FEA=mRNA /GEN=CYP3A4 /PROD=cytochrome P450-3A4 /DB_XREF=gi:6470134 /UG=Hs.178738 cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 /FL=gb:NM_017460.2 gb:M18907.1 gb:AF182273.1 AF182273 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A4 1576 NM_001202855 /// NM_001202856 /// NM_001202857 /// NM_017460 0006629 // lipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0008209 // androgen metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0036378 // calcitriol biosynthetic process from calciol // inferred from direct assay /// 0042359 // vitamin D metabolic process // inferred by curator /// 0042737 // drug catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005496 // steroid binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from direct assay /// 0033780 // taurochenodeoxycholate 6alpha-hydroxylase activity // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047638 // albendazole monooxygenase activity // inferred from electronic annotation /// 0050591 // quinine 3-monooxygenase activity // inferred from electronic annotation /// 0050649 // testosterone 6-beta-hydroxylase activity // inferred from mutant phenotype /// 0070576 // vitamin D 24-hydroxylase activity // inferred from direct assay 206000_at NM_005588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005588.1 /DEF=Homo sapiens meprin A, alpha (PABA peptide hydrolase) (MEP1A), mRNA. /FEA=mRNA /GEN=MEP1A /PROD=meprin A, alpha (PABA peptide hydrolase) /DB_XREF=gi:5031908 /UG=Hs.179704 meprin A, alpha (PABA peptide hydrolase) /FL=gb:NM_005588.1 gb:M82962.1 NM_005588 meprin A, alpha (PABA peptide hydrolase) MEP1A 4224 NM_005588 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017090 // meprin A complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206001_at NM_000905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000905.1 /DEF=Homo sapiens neuropeptide Y (NPY), mRNA. /FEA=mRNA /GEN=NPY /PROD=neuropeptide Y /DB_XREF=gi:4505448 /UG=Hs.1832 neuropeptide Y /FL=gb:K01911.1 gb:M15789.1 gb:NM_000905.1 NM_000905 neuropeptide Y NPY 4852 NM_000905 0006816 // calcium ion transport // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007586 // digestion // non-traceable author statement /// 0007610 // behavior // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008015 // blood circulation // non-traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008343 // adult feeding behavior // inferred from sequence or structural similarity /// 0021954 // central nervous system neuron development // inferred from expression pattern /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0031175 // neuron projection development // inferred from expression pattern /// 0032100 // positive regulation of appetite // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005623 // cell // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement 206002_at NM_005756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005756.1 /DEF=Homo sapiens G protein-coupled receptor 64 (GPR64), mRNA. /FEA=mRNA /GEN=GPR64 /PROD=G protein-coupled receptor 64 /DB_XREF=gi:5031732 /UG=Hs.184942 G protein-coupled receptor 64 /FL=gb:NM_005756.1 NM_005756 G protein-coupled receptor 64 GPR64 10149 NM_001079858 /// NM_001079859 /// NM_001079860 /// NM_001184833 /// NM_001184834 /// NM_001184835 /// NM_001184836 /// NM_001184837 /// NM_005756 /// XM_006724449 /// XM_006724450 /// XM_006724451 /// XM_006724452 /// XM_006724453 /// XM_006724454 /// XM_006724455 /// XM_006724456 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 206003_at NM_014645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014645.1 /DEF=Homo sapiens KIAA0635 gene product (KIAA0635), mRNA. /FEA=mRNA /GEN=KIAA0635 /PROD=KIAA0635 gene product /DB_XREF=gi:7662215 /UG=Hs.185091 KIAA0635 gene product /FL=gb:AB014535.1 gb:NM_014645.1 NM_014645 centrosomal protein 135kDa CEP135 9662 NM_014645 /// NM_025009 /// XM_005265788 /// XM_006714055 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction 206004_at NM_003245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003245.1 /DEF=Homo sapiens transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3), mRNA. /FEA=mRNA /GEN=TGM3 /PROD=transglutaminase 3 (E polypeptide,protein-glutamine-gamma-glutamyltransferase) /DB_XREF=gi:4507476 /UG=Hs.2022 transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:L10386.1 gb:NM_003245.1 NM_003245 transglutaminase 3 TGM3 7053 NM_003245 /// XM_006723615 0006184 // GTP catabolic process // inferred from direct assay /// 0006464 // cellular protein modification process // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030216 // keratinocyte differentiation // traceable author statement /// 0031069 // hair follicle morphogenesis // traceable author statement /// 0031424 // keratinization // inferred from electronic annotation /// 0043163 // cell envelope organization // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0019003 // GDP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206005_s_at AK023613 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023613.1 /DEF=Homo sapiens cDNA FLJ13551 fis, clone PLACE1007140, weakly similar to TRICHOHYALIN. /FEA=mRNA /DB_XREF=gi:10435593 /UG=Hs.202276 KIAA1009 protein /FL=gb:AB023226.1 gb:NM_014895.1 AK023613 centrosomal protein 162kDa CEP162 22832 NM_001286206 /// NM_014895 /// XM_005248674 /// XM_005248675 /// XM_005248678 /// XM_006715380 /// XR_241844 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005879 // axonemal microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206006_s_at NM_014895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014895.1 /DEF=Homo sapiens KIAA1009 protein (KIAA1009), mRNA. /FEA=mRNA /GEN=KIAA1009 /PROD=KIAA1009 protein /DB_XREF=gi:7662445 /UG=Hs.202276 KIAA1009 protein /FL=gb:AB023226.1 gb:NM_014895.1 NM_014895 centrosomal protein 162kDa CEP162 22832 NM_001286206 /// NM_014895 /// XM_005248674 /// XM_005248675 /// XM_005248678 /// XM_006715380 /// XR_241844 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005879 // axonemal microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206007_at NM_005807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005807.1 /DEF=Homo sapiens proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein) (PRG4), mRNA. /FEA=mRNA /GEN=PRG4 /PROD=megakaryocyte stimulating factor /DB_XREF=gi:5031924 /UG=Hs.218791 proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein) /FL=gb:U70136.1 gb:NM_005807.1 NM_005807 proteoglycan 4 PRG4 10216 NM_001127708 /// NM_001127709 /// NM_001127710 /// NM_005807 /// XM_005244822 /// XM_006711108 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206008_at NM_000359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000359.1 /DEF=Homo sapiens transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1), mRNA. /FEA=mRNA /GEN=TGM1 /PROD=transglutaminase 1 (K polypeptide epidermal typeI, protein-glutamine-gamma-glutamyltransferase) /DB_XREF=gi:4507474 /UG=Hs.22 transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) /FL=gb:M55183.1 gb:D90287.1 gb:M62925.1 gb:NM_000359.1 NM_000359 transglutaminase 1 TGM1 7051 NM_000359 0006464 // cellular protein modification process // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation /// 0043163 // cell envelope organization // traceable author statement 0001533 // cornified envelope // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206009_at NM_002207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002207.1 /DEF=Homo sapiens integin, alpha 9 (ITGA9), mRNA. /FEA=mRNA /GEN=ITGA9 /PROD=integin, alpha 9 /DB_XREF=gi:11321594 /UG=Hs.222 integrin, alpha 9 /FL=gb:NM_002207.1 gb:D25303.1 NM_002207 integrin, alpha 9 ITGA9 3680 NM_002207 0007155 // cell adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206010_at NM_004132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004132.1 /DEF=Homo sapiens hyaluronan-binding protein 2 (HABP2), mRNA. /FEA=mRNA /GEN=HABP2 /PROD=hyaluronan-binding protein 2 /DB_XREF=gi:4758501 /UG=Hs.241363 hyaluronan-binding protein 2 /FL=gb:NM_004132.1 gb:D49742.1 NM_004132 hyaluronan binding protein 2 HABP2 3026 NM_001177660 /// NM_004132 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206011_at AI719655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI719655 /FEA=EST /DB_XREF=gi:5036911 /DB_XREF=est:at14e10.x1 /CLONE=IMAGE:2355114 /UG=Hs.2490 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) /FL=gb:NM_001223.1 gb:U13697.1 AI719655 caspase 1, apoptosis-related cysteine peptidase CASP1 834 NM_001223 /// NM_001257118 /// NM_001257119 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 /// XM_006718924 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0051882 // mitochondrial depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070269 // pyroptosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0097194 // execution phase of apoptosis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0072557 // IPAF inflammasome complex // not recorded /// 0072557 // IPAF inflammasome complex // inferred from sequence or structural similarity /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 206012_at NM_003240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003240.1 /DEF=Homo sapiens endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily) (EBAF), mRNA. /FEA=mRNA /GEN=EBAF /PROD=transforming growth factor, beta 4 /DB_XREF=gi:4503440 /UG=Hs.25195 endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily) /FL=gb:U81523.1 gb:NM_003240.1 gb:AF081513.1 NM_003240 left-right determination factor 1 /// left-right determination factor 2 LEFTY1 /// LEFTY2 7044 /// 10637 NM_001172425 /// NM_003240 /// NM_020997 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206013_s_at NM_016188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016188.2 /DEF=Homo sapiens actin-like 6 (ACTL6), mRNA. /FEA=mRNA /GEN=ACTL6 /PROD=BAF53b /DB_XREF=gi:11761635 /UG=Hs.259831 actin-like 6 /FL=gb:NM_016188.2 gb:AB015906.1 gb:AF041475.1 NM_016188 actin-like 6B ACTL6B 51412 NM_016188 /// XM_006716020 0006325 // chromatin organization // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement 206014_at NM_016188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016188.2 /DEF=Homo sapiens actin-like 6 (ACTL6), mRNA. /FEA=mRNA /GEN=ACTL6 /PROD=BAF53b /DB_XREF=gi:11761635 /UG=Hs.259831 actin-like 6 /FL=gb:NM_016188.2 gb:AB015906.1 gb:AF041475.1 NM_016188 actin-like 6B ACTL6B 51412 NM_016188 /// XM_006716020 0006325 // chromatin organization // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement 206015_s_at NM_014947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014947.1 /DEF=Homo sapiens KIAA1041 protein (KIAA1041), mRNA. /FEA=mRNA /GEN=KIAA1041 /PROD=KIAA1041 protein /DB_XREF=gi:7662455 /UG=Hs.26023 KIAA1041 protein /FL=gb:AB028964.1 gb:NM_014947.1 NM_014947 forkhead box J3 FOXJ3 22887 NM_001198850 /// NM_001198851 /// NM_001198852 /// NM_014947 /// XM_005270632 /// XM_006710458 /// XM_006710459 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206016_at NM_014008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014008.1 /DEF=Homo sapiens JM1 protein (JM1), mRNA. /FEA=mRNA /GEN=JM1 /PROD=JM1 protein /DB_XREF=gi:7661843 /UG=Hs.26333 JM1 protein /FL=gb:BC000972.2 gb:AJ005890.1 gb:NM_014008.1 NM_014008 coiled-coil domain containing 22 CCDC22 28952 NM_014008 /// XM_005272599 /// XR_430506 0005515 // protein binding // inferred from electronic annotation 206017_at NM_014809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014809.1 /DEF=Homo sapiens KIAA0319 gene product (KIAA0319), mRNA. /FEA=mRNA /GEN=KIAA0319 /PROD=KIAA0319 gene product /DB_XREF=gi:7662053 /UG=Hs.26441 KIAA0319 gene product /FL=gb:AB002317.1 gb:NM_014809.1 NM_014809 KIAA0319 KIAA0319 9856 NM_001168374 /// NM_001168375 /// NM_001168376 /// NM_001168377 /// NM_001252328 /// NM_014809 /// XM_005249504 /// XM_006715286 /// XM_006715287 /// XM_006715288 0001764 // neuron migration // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 2000171 // negative regulation of dendrite development // inferred from genetic interaction 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206018_at NM_005249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005249.1 /DEF=Homo sapiens forkhead box G1B (FOXG1B), mRNA. /FEA=mRNA /GEN=FOXG1B /PROD=forkhead box G1B /DB_XREF=gi:4885238 /UG=Hs.2714 forkhead box G1B /FL=gb:NM_005249.1 NM_005249 forkhead box G1 FOXG1 2290 NM_005249 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from electronic annotation /// 0021852 // pyramidal neuron migration // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206019_at NM_014852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014852.1 /DEF=Homo sapiens KIAA0682 gene product (KIAA0682), mRNA. /FEA=mRNA /GEN=KIAA0682 /PROD=KIAA0682 gene product /DB_XREF=gi:7662249 /UG=Hs.278496 KIAA0682 gene product /FL=gb:AB014582.1 gb:NM_014852.1 NM_014852 RNA binding motif protein 19 RBM19 9904 NM_001146698 /// NM_001146699 /// NM_016196 0007275 // multicellular organismal development // inferred from electronic annotation /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 206020_at NM_016387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016387.1 /DEF=Homo sapiens hypothetical protein (HSPC060), mRNA. /FEA=mRNA /GEN=HSPC060 /PROD=hypothetical protein /DB_XREF=gi:7705444 /UG=Hs.279883 hypothetical protein /FL=gb:AF161545.1 gb:NM_016387.1 NM_016387 suppressor of cytokine signaling 6 SOCS6 9306 NM_004232 /// XM_005266783 /// XM_006722577 0006952 // defense response // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 206021_at NM_022050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022050.1 /DEF=Homo sapiens SCAN domain-containing 2 (SCAND2), mRNA. /FEA=mRNA /GEN=SCAND2 /PROD=SCAN domain-containing 2 /DB_XREF=gi:11545754 /UG=Hs.283825 SCAN domain-containing 2 /FL=gb:AF229246.1 gb:NM_022050.1 NM_022050 SCAN domain containing 2 pseudogene SCAND2P 54581 NM_022050 /// NM_033633 /// NM_033634 /// NM_033635 /// NM_033636 /// NM_033640 /// NR_003654 /// NR_004859 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 206022_at NM_000266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000266.1 /DEF=Homo sapiens Norrie disease (pseudoglioma) (NDP), mRNA. /FEA=mRNA /GEN=NDP /PROD=Norrie disease protein /DB_XREF=gi:4557788 /UG=Hs.2839 Norrie disease (pseudoglioma) /FL=gb:NM_000266.1 NM_000266 Norrie disease (pseudoglioma) NDP 4693 NM_000266 0001890 // placenta development // inferred from electronic annotation /// 0007033 // vacuole organization // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007605 // sensory perception of sound // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0035426 // extracellular matrix-cell signaling // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005109 // frizzled binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction 206023_at NM_006681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006681.1 /DEF=Homo sapiens neuromedin U (NMU), mRNA. /FEA=mRNA /GEN=NMU /PROD=neuromedin U /DB_XREF=gi:5729946 /UG=Hs.2841 neuromedin U /FL=gb:NM_006681.1 NM_006681 neuromedin U NMU 10874 NM_001292045 /// NM_001292046 /// NM_006681 /// NR_120489 /// XM_005265713 0001696 // gastric acid secretion // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0009648 // photoperiodism // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0043195 // terminal bouton // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0042922 // neuromedin U receptor binding // inferred from electronic annotation 206024_at NM_002150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002150.1 /DEF=Homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), mRNA. /FEA=mRNA /GEN=HPD /PROD=4-hydroxyphenylpyruvate dioxygenase /DB_XREF=gi:4504476 /UG=Hs.2899 4-hydroxyphenylpyruvate dioxygenase /FL=gb:NM_002150.1 NM_002150 4-hydroxyphenylpyruvate dioxygenase HPD 3242 NM_001171993 /// NM_002150 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from sequence or structural similarity /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003868 // 4-hydroxyphenylpyruvate dioxygenase activity // not recorded /// 0003868 // 4-hydroxyphenylpyruvate dioxygenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016701 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 206025_s_at AW188198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188198 /FEA=EST /DB_XREF=gi:6462634 /DB_XREF=est:xj93f03.x1 /CLONE=IMAGE:2664797 /UG=Hs.29352 tumor necrosis factor, alpha-induced protein 6 /FL=gb:NM_007115.1 AW188198 tumor necrosis factor, alpha-induced protein 6 TNFAIP6 7130 NM_007115 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005540 // hyaluronic acid binding // inferred from electronic annotation 206026_s_at NM_007115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007115.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 6 (TNFAIP6), mRNA. /FEA=mRNA /GEN=TNFAIP6 /PROD=tumor necrosis factor, alpha-induced protein 6 /DB_XREF=gi:6005905 /UG=Hs.29352 tumor necrosis factor, alpha-induced protein 6 /FL=gb:NM_007115.1 NM_007115 tumor necrosis factor, alpha-induced protein 6 TNFAIP6 7130 NM_007115 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005540 // hyaluronic acid binding // inferred from electronic annotation 206027_at NM_002960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002960.1 /DEF=Homo sapiens S100 calcium-binding protein A3 (S100A3), mRNA. /FEA=mRNA /GEN=S100A3 /PROD=S100 calcium-binding protein A3 /DB_XREF=gi:4506762 /UG=Hs.2961 S100 calcium-binding protein A3 /FL=gb:NM_002960.1 NM_002960 S100 calcium binding protein A3 S100A3 6274 NM_002960 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206028_s_at NM_006343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006343.1 /DEF=Homo sapiens c-mer proto-oncogene tyrosine kinase (MERTK), mRNA. /FEA=mRNA /GEN=MERTK /PROD=c-mer proto-oncogene tyrosine kinase /DB_XREF=gi:5453737 /UG=Hs.306178 c-mer proto-oncogene tyrosine kinase /FL=gb:U08023.1 gb:NM_006343.1 NM_006343 MER proto-oncogene, tyrosine kinase MERTK 10461 NM_006343 /// XM_005263565 /// XM_005263568 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006909 // phagocytosis // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016028 // rhabdomere // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206029_at NM_014391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014391.1 /DEF=Homo sapiens cardiac ankyrin repeat protein (CARP), mRNA. /FEA=mRNA /GEN=CARP /PROD=cardiac ankyrin repeat protein /DB_XREF=gi:7656960 /UG=Hs.31432 cardiac ankyrin repeat protein /FL=gb:NM_014391.1 NM_014391 ankyrin repeat domain 1 (cardiac muscle) ANKRD1 27063 NM_014391 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035994 // response to muscle stretch // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045214 // sarcomere organization // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 2000279 // negative regulation of DNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0031674 // I band // inferred from sequence or structural similarity 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 206030_at NM_000049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000049.1 /DEF=Homo sapiens aspartoacylase (aminoacylase 2, Canavan disease) (ASPA), mRNA. /FEA=mRNA /GEN=ASPA /PROD=aspartoacylase (aminoacylase 2) /DB_XREF=gi:4557334 /UG=Hs.32042 aspartoacylase (aminoacylase 2, Canavan disease) /FL=gb:NM_000049.1 NM_000049 aspartoacylase ASPA 443 NM_000049 /// NM_001128085 /// XM_005256649 /// XM_006721527 0006533 // aspartate catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0019807 // aspartoacylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206031_s_at NM_003481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003481.1 /DEF=Homo sapiens ubiquitin specific protease 5 (isopeptidase T) (USP5), mRNA. /FEA=mRNA /GEN=USP5 /PROD=Ubiquitin isopeptidase T /DB_XREF=gi:4507854 /UG=Hs.3759 ubiquitin specific protease 5 (isopeptidase T) /FL=gb:U35116.1 gb:BC004889.1 gb:NM_003481.1 NM_003481 ubiquitin specific peptidase 5 (isopeptidase T) USP5 8078 NM_001098536 /// NM_003481 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0071108 // protein K48-linked deubiquitination // inferred from mutant phenotype 0005764 // lysosome // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206032_at AI797281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI797281 /FEA=EST /DB_XREF=gi:5362753 /DB_XREF=est:we86g02.x1 /CLONE=IMAGE:2348018 /UG=Hs.41690 desmocollin 3 /FL=gb:NM_001941.2 AI797281 desmocollin 3 DSC3 1825 NM_001941 /// NM_024423 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206033_s_at NM_001941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001941.2 /DEF=Homo sapiens desmocollin 3 (DSC3),transcript variant Dsc3a, mRNA. /FEA=mRNA /GEN=DSC3 /PROD=desmocollin 3, isoform Dsc3a preproprotein /DB_XREF=gi:13435367 /UG=Hs.41690 desmocollin 3 /FL=gb:NM_001941.2 NM_001941 desmocollin 3 DSC3 1825 NM_001941 /// NM_024423 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206034_at NM_002640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002640.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 (SERPINB8), mRNA. /FEA=mRNA /GEN=SERPINB8 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 8 /DB_XREF=gi:4505790 /UG=Hs.41726 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 /FL=gb:L40377.1 gb:NM_002640.1 NM_002640 serpin peptidase inhibitor, clade B (ovalbumin), member 8 SERPINB8 5271 NM_001031848 /// NM_001276490 /// NM_002640 /// NM_198833 /// XM_006722484 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0030162 // regulation of proteolysis // not recorded 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206035_at NM_002908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002908.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), mRNA. /FEA=mRNA /GEN=REL /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog /DB_XREF=gi:4506472 /UG=Hs.44313 v-rel avian reticuloendotheliosis viral oncogene homolog /FL=gb:NM_002908.1 NM_002908 v-rel avian reticuloendotheliosis viral oncogene homolog REL 5966 NM_001291746 /// NM_002908 /// XM_005264470 /// XM_005264471 /// XM_005264472 0001816 // cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206036_s_at NM_002908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002908.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), mRNA. /FEA=mRNA /GEN=REL /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog /DB_XREF=gi:4506472 /UG=Hs.44313 v-rel avian reticuloendotheliosis viral oncogene homolog /FL=gb:NM_002908.1 NM_002908 v-rel avian reticuloendotheliosis viral oncogene homolog REL 5966 NM_001291746 /// NM_002908 /// XM_005264470 /// XM_005264471 /// XM_005264472 0001816 // cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206037_at NM_004059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004059.2 /DEF=Homo sapiens cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) (CCBL1), mRNA. /FEA=mRNA /GEN=CCBL1 /PROD=cytoplasmic cysteine conjugate-beta lyase /DB_XREF=gi:11038631 /UG=Hs.46634 cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) /FL=gb:NM_004059.2 NM_004059 cysteine conjugate-beta lyase, cytoplasmic CCBL1 883 NM_001122671 /// NM_001122672 /// NM_001287390 /// NM_004059 /// NR_109829 /// XM_006717311 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006569 // tryptophan catabolic process // traceable author statement /// 0006575 // cellular modified amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070189 // kynurenine metabolic process // inferred from direct assay /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0008483 // transaminase activity // traceable author statement /// 0016212 // kynurenine-oxoglutarate transaminase activity // not recorded /// 0016212 // kynurenine-oxoglutarate transaminase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0036141 // L-phenylalanine-oxaloacetate transaminase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047312 // L-phenylalanine:pyruvate aminotransferase activity // not recorded /// 0047316 // glutamine-phenylpyruvate transaminase activity // inferred from electronic annotation /// 0047804 // cysteine-S-conjugate beta-lyase activity // inferred from electronic annotation /// 0047945 // L-glutamine:pyruvate aminotransferase activity // not recorded 206038_s_at NM_003298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003298.1 /DEF=Homo sapiens nuclear receptor subfamily 2, group C, member 2 (NR2C2), mRNA. /FEA=mRNA /GEN=NR2C2 /PROD=nuclear receptor subfamily 2, group C, member 2 /DB_XREF=gi:4507674 /UG=Hs.520 nuclear receptor subfamily 2, group C, member 2 /FL=gb:NM_003298.1 gb:L27586.1 NM_003298 nuclear receptor subfamily 2, group C, member 2 NR2C2 7182 NM_001291694 /// NM_003298 /// XM_005265428 /// XM_006713320 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040019 // positive regulation of embryonic development // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048520 // positive regulation of behavior // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 206039_at NM_004794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004794.1 /DEF=Homo sapiens RAB33A, member RAS oncogene family (RAB33A), mRNA. /FEA=mRNA /GEN=RAB33A /PROD=RAB33A, member RAS oncogene family /DB_XREF=gi:4758995 /UG=Hs.56294 RAB33A, member RAS oncogene family /FL=gb:BC001157.1 gb:D14889.1 gb:NM_004794.1 NM_004794 RAB33A, member RAS oncogene family RAB33A 9363 NM_004794 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 206040_s_at NM_002751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002751.1 /DEF=Homo sapiens mitogen-activated protein kinase 11 (MAPK11), mRNA. /FEA=mRNA /GEN=MAPK11 /PROD=mitogen-activated protein kinase 11 /DB_XREF=gi:4506082 /UG=Hs.57732 mitogen-activated protein kinase 11 /FL=gb:AF001008.1 gb:AF001174.1 gb:AF031135.1 gb:NM_002751.1 NM_002751 mitogen-activated protein kinase 11 MAPK11 5600 NM_002751 /// NR_110887 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 206042_x_at NM_022804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022804.1 /DEF=Homo sapiens SNRPN upstream reading frame (SNURF), transcript variant 2, mRNA. /FEA=mRNA /GEN=SNURF /PROD=SNRPN upstream reading frame protein /DB_XREF=gi:13027654 /UG=Hs.58606 SNRPN upstream reading frame /FL=gb:NM_005678.2 gb:NM_022804.1 gb:AF101044.1 NM_022804 small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame SNRPN /// SNURF 6638 /// 8926 NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206043_s_at NM_014861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014861.1 /DEF=Homo sapiens KIAA0703 gene product (KIAA0703), mRNA. /FEA=mRNA /GEN=KIAA0703 /PROD=KIAA0703 gene product /DB_XREF=gi:7662255 /UG=Hs.6168 KIAA0703 gene product /FL=gb:AB014603.1 gb:NM_014861.1 NM_014861 ATPase, Ca++ transporting, type 2C, member 2 ATP2C2 9914 NM_001286527 /// NM_001291454 /// NM_014861 /// XM_006721355 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206044_s_at NM_004333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004333.1 /DEF=Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA. /FEA=mRNA /GEN=BRAF /PROD=v-raf murine sarcoma viral oncogene homolog B1 /DB_XREF=gi:4757867 /UG=Hs.622 v-raf murine sarcoma viral oncogene homolog B1 /FL=gb:M95712.1 gb:NM_004333.1 NM_004333 B-Raf proto-oncogene, serine/threonine kinase /// KIAA1549 BRAF /// KIAA1549 673 /// 57670 NM_001164665 /// NM_004333 /// NM_020910 /// XM_005250045 /// XM_005250046 /// XM_006716071 /// XM_006716072 /// XR_242190 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016442 // RISC complex // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206045_s_at NM_003787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003787.1 /DEF=Homo sapiens nucleolar protein 4 (NOL4), mRNA. /FEA=mRNA /GEN=NOL4 /PROD=nucleolar protein 4 /DB_XREF=gi:4505420 /UG=Hs.6414 nucleolar protein 4 /FL=gb:AB017800.1 gb:NM_003787.1 NM_003787 nucleolar protein 4 NOL4 8715 NM_001198546 /// NM_001198547 /// NM_001198548 /// NM_001198549 /// NM_001282527 /// NM_003787 /// XM_006722563 /// XM_006722564 /// XM_006722565 /// XM_006722566 /// XM_006722567 /// XM_006722568 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003723 // RNA binding // traceable author statement 206046_at NM_003812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003812.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 23 (ADAM23), mRNA. /FEA=mRNA /GEN=ADAM23 /PROD=a disintegrin and metalloproteinase domain 23preproprotein /DB_XREF=gi:4501912 /UG=Hs.7164 a disintegrin and metalloproteinase domain 23 /FL=gb:AB009672.1 gb:NM_003812.1 NM_003812 ADAM metallopeptidase domain 23 ADAM23 8745 NM_003812 /// XM_005246932 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 206047_at NM_002075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002075.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3 (GNB3), mRNA. /FEA=mRNA /GEN=GNB3 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 3 /DB_XREF=gi:4504052 /UG=Hs.71642 guanine nucleotide binding protein (G protein), beta polypeptide 3 /FL=gb:BC000115.1 gb:BC002454.1 gb:M31328.1 gb:NM_002075.1 NM_002075 guanine nucleotide binding protein (G protein), beta polypeptide 3 GNB3 2784 NM_002075 /// XM_005253680 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from physical interaction 206048_at NM_021220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021220.1 /DEF=Homo sapiens putative zinc finger protein from EUROIMAGE 566589 (LOC58495), mRNA. /FEA=mRNA /GEN=LOC58495 /PROD=putative zinc finger protein from EUROIMAGE566589 /DB_XREF=gi:10864030 /UG=Hs.71935 putative zinc finger protein from EUROIMAGE 566589 /FL=gb:NM_021220.1 NM_021220 ovo-like zinc finger 2 OVOL2 58495 NM_021220 /// XM_005260783 0001525 // angiogenesis // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010837 // regulation of keratinocyte proliferation // inferred from electronic annotation /// 0010837 // regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0045617 // negative regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0060214 // endocardium formation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred by curator 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206049_at NM_003005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003005.2 /DEF=Homo sapiens selectin P (granule membrane protein 140kD, antigen CD62) (SELP), mRNA. /FEA=mRNA /GEN=SELP /PROD=selectin P precursor /DB_XREF=gi:6031196 /UG=Hs.73800 selectin P (granule membrane protein 140kD, antigen CD62) /FL=gb:M25322.1 gb:NM_003005.2 NM_003005 selectin P (granule membrane protein 140kDa, antigen CD62) SELP 6403 NM_003005 /// XM_005245435 /// XM_005245436 /// XM_005245438 /// XM_005245439 /// XM_005245440 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred by curator /// 0033623 // regulation of integrin activation // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // inferred by curator /// 0050900 // leukocyte migration // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031092 // platelet alpha granule membrane // inferred from direct assay /// 0031092 // platelet alpha granule membrane // traceable author statement 0001530 // lipopolysaccharide binding // inferred from mutant phenotype /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from direct assay /// 0042806 // fucose binding // inferred from direct assay /// 0043208 // glycosphingolipid binding // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay 206050_s_at NM_002939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002939.1 /DEF=Homo sapiens ribonucleaseangiogenin inhibitor (RNH), mRNA. /FEA=mRNA /GEN=RNH /PROD=ribonucleaseangiogenin inhibitor /DB_XREF=gi:4506564 /UG=Hs.75108 ribonucleaseangiogenin inhibitor /FL=gb:M36717.1 gb:NM_002939.1 NM_002939 ribonuclease/angiogenin inhibitor 1 RNH1 6050 NM_002939 /// NM_203383 /// NM_203384 /// NM_203385 /// NM_203386 /// NM_203387 /// NM_203388 /// NM_203389 0006402 // mRNA catabolic process // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0032311 // angiogenin-PRI complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008428 // ribonuclease inhibitor activity // inferred from direct assay 206051_at NM_021952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021952.1 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) (ELAVL4), mRNA. /FEA=mRNA /GEN=ELAVL4 /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 4 (Hu antigen D) /DB_XREF=gi:11386162 /UG=Hs.75236 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) /FL=gb:NM_021952.1 gb:M62843.1 NM_021952 ELAV like neuron-specific RNA binding protein 4 ELAVL4 1996 NM_001144774 /// NM_001144775 /// NM_001144776 /// NM_001144777 /// NM_001294348 /// NM_021952 /// XM_005270581 /// XM_006710411 /// XM_006710412 /// XM_006710413 /// XM_006710414 /// XM_006710415 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from direct assay 206052_s_at NM_006527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006527.1 /DEF=Homo sapiens Hairpin binding protein, histone (HBP), mRNA. /FEA=mRNA /GEN=HBP /PROD=Hairpin binding protein, histone /DB_XREF=gi:5729861 /UG=Hs.75257 stem-loop (histone) binding protein /FL=gb:U75679.1 gb:NM_006527.1 NM_006527 stem-loop binding protein SLBP 7884 NM_006527 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006398 // histone mRNA 3'-end processing // inferred from sequence or structural similarity /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0033260 // nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071207 // histone pre-mRNA stem-loop binding // inferred from sequence or structural similarity /// 0071208 // histone pre-mRNA DCP binding // inferred from sequence or structural similarity 206053_at NM_014930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014930.1 /DEF=Homo sapiens KIAA0972 protein (KIAA0972), mRNA. /FEA=mRNA /GEN=KIAA0972 /PROD=KIAA0972 protein /DB_XREF=gi:7662423 /UG=Hs.75264 KIAA0972 protein /FL=gb:AB023189.1 gb:NM_014930.1 NM_014930 zinc finger protein 510 ZNF510 22869 NM_014930 /// XM_005251807 /// XM_005251808 /// XM_005251809 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206054_at NM_000893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000893.1 /DEF=Homo sapiens kininogen (KNG), mRNA. /FEA=mRNA /GEN=KNG /PROD=kininogen /DB_XREF=gi:4504892 /UG=Hs.77741 kininogen /FL=gb:NM_000893.1 NM_000893 kininogen 1 KNG1 3827 NM_000893 /// NM_001102416 /// NM_001166451 0002576 // platelet degranulation // traceable author statement /// 0006939 // smooth muscle contraction // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0035810 // positive regulation of urine volume // traceable author statement /// 0035815 // positive regulation of renal sodium excretion // traceable author statement /// 0042311 // vasodilation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206055_s_at NM_003090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003090.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA1), mRNA. /FEA=mRNA /GEN=SNRPA1 /PROD=small nuclear ribonucleoprotein polypeptide A /DB_XREF=gi:4507120 /UG=Hs.80506 small nuclear ribonucleoprotein polypeptide A /FL=gb:NM_003090.1 NM_003090 small nuclear ribonucleoprotein polypeptide A' SNRPA1 6627 NM_003090 /// XR_243213 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005686 // U2 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 206056_x_at X52075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52075 /DEF=Human gene for sialophorin (CD43) /FEA=mRNA /DB_XREF=gi:36455 /UG=Hs.80738 sialophorin (gpL115, leukosialin, CD43) /FL=gb:J04536.1 gb:NM_003123.1 X52075 leukosialin-like /// sialophorin LOC101929889 /// SPN 6693 /// 101929889 NM_001030288 /// NM_003123 /// XM_005276513 0001562 // response to protozoan // inferred from electronic annotation /// 0001808 // negative regulation of type IV hypersensitivity // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001931 // uropod // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 206057_x_at NM_003123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003123.1 /DEF=Homo sapiens sialophorin (gpL115, leukosialin, CD43) (SPN), mRNA. /FEA=mRNA /GEN=SPN /PROD=sialophorin (gpL115, leukosialin, CD43) /DB_XREF=gi:4507180 /UG=Hs.80738 sialophorin (gpL115, leukosialin, CD43) /FL=gb:J04536.1 gb:NM_003123.1 NM_003123 leukosialin-like /// sialophorin LOC101929889 /// SPN 6693 /// 101929889 NM_001030288 /// NM_003123 /// XM_005276513 0001562 // response to protozoan // inferred from electronic annotation /// 0001808 // negative regulation of type IV hypersensitivity // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001931 // uropod // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 206058_at U27699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27699.1 /DEF=Human pephBGT-1 betaine-GABA transporter mRNA, complete cds. /FEA=mRNA /PROD=pephBGT-1 betaine-GABA transporter /DB_XREF=gi:881474 /UG=Hs.82535 solute carrier family 6 (neurotransmitter transporter, betaineGABA), member 12 /FL=gb:NM_003044.1 gb:L42300.1 gb:U27699.1 U27699 solute carrier family 6 (neurotransmitter transporter), member 12 SLC6A12 6539 NM_001122847 /// NM_001122848 /// NM_001206931 /// NM_003044 /// XM_005253746 /// XM_005253747 /// XM_005253748 /// XM_006719005 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009992 // cellular water homeostasis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015812 // gamma-aminobutyric acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071474 // cellular hyperosmotic response // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005332 // gamma-aminobutyric acid:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 206059_at NM_003430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003430.1 /DEF=Homo sapiens zinc finger protein 91 (HPF7, HTF10) (ZNF91), mRNA. /FEA=mRNA /GEN=ZNF91 /PROD=zinc finger protein 91 (HPF7, HTF10) /DB_XREF=gi:4508040 /UG=Hs.8597 zinc finger protein 91 (HPF7, HTF10) /FL=gb:L11672.1 gb:NM_003430.1 NM_003430 zinc finger protein 91 ZNF91 7644 NM_003430 /// XM_006722878 /// XM_006722879 /// XM_006722880 /// XM_006722881 /// XR_430154 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206060_s_at NM_015967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015967.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), mRNA. /FEA=mRNA /GEN=PTPN22 /PROD=protein tyrosine phosphatase homolog /DB_XREF=gi:7706279 /UG=Hs.87860 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) /FL=gb:AF001846.1 gb:AF077031.1 gb:NM_015967.1 NM_015967 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) PTPN22 26191 NM_001193431 /// NM_012411 /// NM_015967 /// XM_005270738 0002376 // immune system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0032817 // regulation of natural killer cell proliferation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035644 // phosphoanandamide dephosphorylation // inferred from sequence or structural similarity /// 0045088 // regulation of innate immune response // inferred by curator /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0019900 // kinase binding // inferred from sequence or structural similarity 206061_s_at NM_030621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030621.1 /DEF=Homo sapiens helicase-moi (KIAA0928), mRNA. /FEA=mRNA /GEN=KIAA0928 /PROD=helicase-moi /DB_XREF=gi:13449288 /UG=Hs.87889 helicase-moi /FL=gb:NM_030621.1 gb:AB028449.1 NM_030621 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206062_at L36861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L36861 /DEF=Homo sapiens guanylate cyclase activating protein (GCAP) gene exons 1-4, complete cds /FEA=mRNA /DB_XREF=gi:623404 /UG=Hs.92858 guanylate cyclase activator 1A (retina) /FL=gb:NM_000409.1 gb:L36859.1 L36861 guanylate cyclase activator 1A (retina) GUCA1A 2978 NM_000409 /// XM_006715073 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206063_x_at BF001594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001594 /FEA=EST /DB_XREF=gi:10701869 /DB_XREF=est:7g90d12.x1 /CLONE=IMAGE:3313751 /UG=Hs.93523 peptidylprolyl isomerase (cyclophilin)-like 2 /FL=gb:U37219.1 gb:NM_014337.1 BF001594 peptidylprolyl isomerase (cyclophilin)-like 2 PPIL2 23759 NM_014337 /// NM_148175 /// NM_148176 /// XM_005261447 /// XM_005261448 /// XM_006724197 /// XM_006724198 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 206064_s_at NM_014337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014337.1 /DEF=Homo sapiens peptidylprolyl isomerase (cyclophilin)-like 2 (PPIL2), mRNA. /FEA=mRNA /GEN=PPIL2 /PROD=peptidylprolyl isomerase (cyclophilin)-like 2 /DB_XREF=gi:7657472 /UG=Hs.93523 peptidylprolyl isomerase (cyclophilin)-like 2 /FL=gb:U37219.1 gb:NM_014337.1 NM_014337 peptidylprolyl isomerase (cyclophilin)-like 2 PPIL2 23759 NM_014337 /// NM_148175 /// NM_148176 /// XM_005261447 /// XM_005261448 /// XM_006724197 /// XM_006724198 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 206065_s_at NM_001385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001385.1 /DEF=Homo sapiens dihydropyrimidinase (DPYS), mRNA. /FEA=mRNA /GEN=DPYS /PROD=dihydropyrimidinase /DB_XREF=gi:4503374 /UG=Hs.10755 dihydropyrimidinase /FL=gb:D78011.1 gb:NM_001385.1 NM_001385 dihydropyrimidinase DPYS 1807 NM_001385 /// XM_005250818 /// XM_005250819 /// XM_006716517 /// XM_006716518 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from direct assay /// 0006210 // thymine catabolic process // inferred from sequence or structural similarity /// 0006212 // uracil catabolic process // inferred from direct assay /// 0006212 // uracil catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0019482 // beta-alanine metabolic process // inferred from electronic annotation /// 0019860 // uracil metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002058 // uracil binding // inferred from electronic annotation /// 0002059 // thymine binding // inferred from electronic annotation /// 0004157 // dihydropyrimidinase activity // inferred from direct assay /// 0004157 // dihydropyrimidinase activity // inferred from mutant phenotype /// 0004157 // dihydropyrimidinase activity // traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 206066_s_at NM_002876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002876.1 /DEF=Homo sapiens RAD51 (S. cerevisiae) homolog C (RAD51C), mRNA. /FEA=mRNA /GEN=RAD51C /PROD=RAD51 (S. cerevisiae) homolog C /DB_XREF=gi:4506390 /UG=Hs.11393 RAD51 (S. cerevisiae) homolog C /FL=gb:AF029670.1 gb:NM_002876.1 NM_002876 RAD51 paralog C RAD51C 5889 NM_002876 /// NM_058216 /// NR_103872 /// NR_103873 /// XM_006722001 /// XM_006722002 /// XM_006722003 /// XM_006722004 /// XM_006722005 /// XM_006722006 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006310 // DNA recombination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from sequence or structural similarity /// 0007066 // female meiosis sister chromatid cohesion // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay /// 0033065 // Rad51C-XRCC3 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048476 // Holliday junction resolvase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 206067_s_at NM_024426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024426.1 /DEF=Homo sapiens Wilms tumor 1 (WT1), transcript variant D, mRNA. /FEA=mRNA /GEN=WT1 /PROD=Wilms tumor 1 isoform D /DB_XREF=gi:13386509 /UG=Hs.1145 Wilms tumor 1 /FL=gb:NM_024424.1 gb:NM_024426.1 NM_024426 Wilms tumor 1 WT1 7490 NM_000378 /// NM_001198551 /// NM_001198552 /// NM_024424 /// NM_024425 /// NM_024426 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from genetic interaction /// 0001822 // kidney development // inferred from genetic interaction /// 0001823 // mesonephros development // inferred from electronic annotation /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007281 // germ cell development // inferred from sequence or structural similarity /// 0007356 // thorax and anterior abdomen determination // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from genetic interaction /// 0007530 // sex determination // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008406 // gonad development // inferred from sequence or structural similarity /// 0008584 // male gonad development // inferred from expression pattern /// 0009888 // tissue development // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030325 // adrenal gland development // inferred from genetic interaction /// 0030539 // male genitalia development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from genetic interaction /// 0032836 // glomerular basement membrane development // inferred from mutant phenotype /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0060421 // positive regulation of heart growth // inferred from sequence or structural similarity /// 0060539 // diaphragm development // inferred from sequence or structural similarity /// 0060923 // cardiac muscle cell fate commitment // inferred from sequence or structural similarity /// 0061032 // visceral serous pericardium development // inferred from genetic interaction /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // not recorded /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 0072166 // posterior mesonephric tubule development // inferred from sequence or structural similarity /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from genetic interaction /// 0072302 // negative regulation of metanephric glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2000195 // negative regulation of female gonad development // inferred from sequence or structural similarity /// 2001076 // positive regulation of metanephric ureteric bud development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 206068_s_at AI367275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI367275 /FEA=EST /DB_XREF=gi:4137020 /DB_XREF=est:qz42d01.x1 /CLONE=IMAGE:2029537 /UG=Hs.1209 acyl-Coenzyme A dehydrogenase, long chain /FL=gb:M74096.1 gb:NM_001608.1 AI367275 acyl-CoA dehydrogenase, long chain ACADL 33 NM_001608 /// XM_005246517 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from sequence or structural similarity /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from sequence or structural similarity /// 0042413 // carnitine catabolic process // inferred from sequence or structural similarity /// 0042758 // long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044242 // cellular lipid catabolic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0090181 // regulation of cholesterol metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004466 // long-chain-acyl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016401 // palmitoyl-CoA oxidase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 206069_s_at NM_001608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001608.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, long chain (ACADL), mRNA. /FEA=mRNA /GEN=ACADL /PROD=acyl-Coenzyme A dehydrogenase, long chainprecursor /DB_XREF=gi:4501856 /UG=Hs.1209 acyl-Coenzyme A dehydrogenase, long chain /FL=gb:M74096.1 gb:NM_001608.1 NM_001608 acyl-CoA dehydrogenase, long chain ACADL 33 NM_001608 /// XM_005246517 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from sequence or structural similarity /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from sequence or structural similarity /// 0042413 // carnitine catabolic process // inferred from sequence or structural similarity /// 0042758 // long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044242 // cellular lipid catabolic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0090181 // regulation of cholesterol metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004466 // long-chain-acyl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016401 // palmitoyl-CoA oxidase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 206070_s_at AF213459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF213459.1 /DEF=Homo sapiens ephrin receptor EPHA3 complete form (EPHA3) mRNA, complete cds. /FEA=mRNA /GEN=EPHA3 /PROD=ephrin receptor EPHA3 complete form /DB_XREF=gi:12003434 /UG=Hs.123642 EphA3 /FL=gb:AF213459.1 gb:M83941.1 gb:NM_005233.1 AF213459 EPH receptor A3 EPHA3 2042 NM_005233 /// NM_182644 /// XM_005264715 /// XM_005264716 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity /// 0097156 // fasciculation of motor neuron axon // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206071_s_at NM_005233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005233.1 /DEF=Homo sapiens EphA3 (EPHA3), mRNA. /FEA=mRNA /GEN=EPHA3 /PROD=EphA3 /DB_XREF=gi:4885210 /UG=Hs.123642 EphA3 /FL=gb:AF213459.1 gb:M83941.1 gb:NM_005233.1 NM_005233 EPH receptor A3 EPHA3 2042 NM_005233 /// NM_182644 /// XM_005264715 /// XM_005264716 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity /// 0097156 // fasciculation of motor neuron axon // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206072_at NM_003353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003353.2 /DEF=Homo sapiens urocortin (UCN), mRNA. /FEA=mRNA /GEN=UCN /PROD=urocortin preproprotein /DB_XREF=gi:12056477 /UG=Hs.134932 urocortin /FL=gb:NM_003353.2 NM_003353 urocortin UCN 7349 NM_003353 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030157 // pancreatic juice secretion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031064 // negative regulation of histone deacetylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // inferred from electronic annotation /// 0035483 // gastric emptying // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051461 // positive regulation of corticotropin secretion // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060455 // negative regulation of gastric acid secretion // inferred from electronic annotation /// 0060547 // negative regulation of necrotic cell death // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043196 // varicosity // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046811 // histone deacetylase inhibitor activity // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation /// 0051431 // corticotropin-releasing hormone receptor 2 binding // inferred from electronic annotation 206073_at AF057036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF057036.1 /DEF=Homo sapiens acetylcholinesterase collagen-like tail subunit (COLQ) mRNA, complete cds. /FEA=mRNA /GEN=COLQ /PROD=acetylcholinesterase collagen-like tail subunit /DB_XREF=gi:3378117 /UG=Hs.138520 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase /FL=gb:AF057036.1 gb:NM_005677.1 AF057036 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase COLQ 8292 NM_005677 /// NM_080538 /// NM_080539 /// NM_080540 /// NM_080541 /// NM_080542 /// NM_080543 /// NM_080544 0001507 // acetylcholine catabolic process in synaptic cleft // traceable author statement /// 0008105 // asymmetric protein localization // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005605 // basal lamina // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206074_s_at NM_002131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002131.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein isoforms I and Y (HMGIY), mRNA. /FEA=mRNA /GEN=HMGIY /PROD=high-mobility group (nonhistone chromosomal)protein isoforms I and Y /DB_XREF=gi:4504432 /UG=Hs.139800 high-mobility group (nonhistone chromosomal) protein isoforms I and Y /FL=gb:BC004924.1 gb:NM_002131.1 NM_002131 high mobility group AT-hook 1 HMGA1 3159 NM_002131 /// NM_145899 /// NM_145901 /// NM_145902 /// NM_145903 /// NM_145904 /// NM_145905 /// XM_005249061 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // non-traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from expression pattern /// 0016032 // viral process // traceable author statement /// 0031936 // negative regulation of chromatin silencing // traceable author statement /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0075713 // establishment of integrated proviral latency // traceable author statement /// 0090402 // oncogene-induced cell senescence // inferred from direct assay /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003680 // AT DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0042975 // peroxisome proliferator activated receptor binding // inferred from direct assay /// 0046965 // retinoid X receptor binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from direct assay 206075_s_at NM_001895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001895.1 /DEF=Homo sapiens casein kinase 2, alpha 1 polypeptide (CSNK2A1), mRNA. /FEA=mRNA /GEN=CSNK2A1 /PROD=casein kinase 2, alpha 1 polypeptide /DB_XREF=gi:4503094 /UG=Hs.155140 casein kinase 2, alpha 1 polypeptide /FL=gb:M55265.1 gb:NM_001895.1 gb:J02853.1 NM_001895 casein kinase 2, alpha 1 polypeptide CSNK2A1 1457 NM_001895 /// NM_177559 /// NM_177560 /// XM_006723548 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // traceable author statement /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005956 // protein kinase CK2 complex // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement 206076_at NM_006992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006992.1 /DEF=Homo sapiens B7 protein (B7), mRNA. /FEA=mRNA /GEN=B7 /PROD=B7 protein /DB_XREF=gi:5901897 /UG=Hs.155586 B7 protein /FL=gb:U72508.1 gb:NM_006992.1 NM_006992 leucine rich repeat containing 23 LRRC23 10233 NM_001135217 /// NM_006992 /// NM_201650 0005515 // protein binding // inferred from electronic annotation 206077_at NM_000420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000420.1 /DEF=Homo sapiens Kell blood group (KEL), mRNA. /FEA=mRNA /GEN=KEL /PROD=Kell blood group antigen /DB_XREF=gi:4557690 /UG=Hs.157 Kell blood group /FL=gb:BC003135.1 gb:NM_000420.1 NM_000420 Kell blood group, metallo-endopeptidase KEL 3792 NM_000420 /// XM_005249993 /// XM_005249994 /// XM_005249995 /// XM_005276988 /// XM_005276989 /// XM_005276990 0006508 // proteolysis // inferred from electronic annotation /// 0042310 // vasoconstriction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206078_at NM_007064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007064.1 /DEF=Homo sapiens serinethreonine kinase with Dbl- and pleckstrin homology domains (TRAD), mRNA. /FEA=mRNA /GEN=TRAD /PROD=serinethreonine kinase with Dbl- and pleckstrinhomology domains /DB_XREF=gi:5902139 /UG=Hs.162189 serinethreonine kinase with Dbl- and pleckstrin homology domains /FL=gb:AB011422.1 gb:NM_007064.1 NM_007064 kalirin, RhoGEF kinase KALRN 8997 NM_001024660 /// NM_003947 /// NM_007064 /// NR_028136 /// XM_006713810 /// XM_006713811 /// XM_006713812 /// XM_006713813 /// XM_006713814 /// XM_006713815 /// XM_006713816 /// XM_006713817 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206079_at NM_001821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001821.1 /DEF=Homo sapiens choroideremia-like (Rab escort protein 2) (CHML), mRNA. /FEA=mRNA /GEN=CHML /PROD=choroideremia-like Rab escort protein 2 /DB_XREF=gi:4502810 /UG=Hs.170129 choroideremia-like (Rab escort protein 2) /FL=gb:NM_001821.1 NM_001821 choroideremia-like (Rab escort protein 2) CHML 1122 NM_001821 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0018344 // protein geranylgeranylation // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from mutant phenotype 0004663 // Rab geranylgeranyltransferase activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 206080_at NM_014638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014638.1 /DEF=Homo sapiens KIAA0450 gene product (KIAA0450), mRNA. /FEA=mRNA /GEN=KIAA0450 /PROD=KIAA0450 gene product /DB_XREF=gi:7662133 /UG=Hs.170156 KIAA0450 gene product /FL=gb:AB007919.1 gb:NM_014638.1 NM_014638 phospholipase C, eta 2 PLCH2 9651 NM_014638 /// XM_006711054 /// XM_006711055 /// XM_006724949 /// XM_006724950 /// XM_006724951 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050429 // calcium-dependent phospholipase C activity // inferred from electronic annotation 206081_at NM_004727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004727.1 /DEF=Homo sapiens solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 1 (SLC24A1), mRNA. /FEA=mRNA /GEN=SLC24A1 /PROD=solute carrier family 24(sodiumpotassiumcalcium exchanger), member 1 /DB_XREF=gi:4759127 /UG=Hs.173092 solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 1 /FL=gb:AF062921.1 gb:AF062922.1 gb:NM_004727.1 NM_004727 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 SLC24A1 9187 NM_001254740 /// NM_004727 /// XM_005254778 /// XM_005254779 /// XM_005254780 /// XM_005254781 /// XM_006720764 /// XM_006720765 /// XM_006720766 /// XM_006720767 /// XM_006720768 /// XM_006720769 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007601 // visual perception // non-traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009642 // response to light intensity // non-traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019867 // outer membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008273 // calcium, potassium:sodium antiporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 206082_at NM_006674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006674.1 /DEF=Homo sapiens MHC class I region ORF (P5-1), mRNA. /FEA=mRNA /GEN=P5-1 /PROD=MHC class I region ORF /DB_XREF=gi:5729965 /UG=Hs.1845 MHC class I region ORF /FL=gb:L06175.1 gb:NM_006674.1 NM_006674 HLA complex P5 (non-protein coding) HCP5 10866 NR_040662 0006952 // defense response // traceable author statement 206083_at NM_001702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001702.1 /DEF=Homo sapiens brain-specific angiogenesis inhibitor 1 (BAI1), mRNA. /FEA=mRNA /GEN=BAI1 /PROD=brain-specific angiogenesis inhibitor 1precursor /DB_XREF=gi:4502354 /UG=Hs.194654 brain-specific angiogenesis inhibitor 1 /FL=gb:AB005297.1 gb:NM_001702.1 NM_001702 brain-specific angiogenesis inhibitor 1 BAI1 575 NM_001702 /// XM_005251015 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206084_at NM_002849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002849.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, R (PTPRR), mRNA. /FEA=mRNA /GEN=PTPRR /PROD=protein tyrosine phosphatase, receptor type, R /DB_XREF=gi:4506324 /UG=Hs.198288 protein tyrosine phosphatase, receptor type, R /FL=gb:U77916.1 gb:U42361.1 gb:NM_002849.1 gb:D64053.1 NM_002849 protein tyrosine phosphatase, receptor type, R PTPRR 5801 NM_001207015 /// NM_001207016 /// NM_002849 /// NM_130846 /// NR_073474 0001701 // in utero embryonic development // inferred from expression pattern /// 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 206085_s_at NM_001902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001902.1 /DEF=Homo sapiens cystathionase (cystathionine gamma-lyase) (CTH), mRNA. /FEA=mRNA /GEN=CTH /PROD=cystathionase (cystathionine gamma-lyase) /DB_XREF=gi:4503124 /UG=Hs.19904 cystathionase (cystathionine gamma-lyase) /FL=gb:NM_001902.1 NM_001902 cystathionine gamma-lyase CTH 1491 NM_001190463 /// NM_001902 /// NM_153742 /// XM_005270509 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006534 // cysteine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018272 // protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from electronic annotation /// 0019346 // transsulfuration // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044524 // protein sulfhydration // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0070814 // hydrogen sulfide biosynthetic process // inferred from direct assay /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004123 // cystathionine gamma-lyase activity // inferred from direct assay /// 0004123 // cystathionine gamma-lyase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016846 // carbon-sulfur lyase activity // traceable author statement /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0044540 // L-cystine L-cysteine-lyase (deaminating) // inferred from mutant phenotype /// 0047982 // homocysteine desulfhydrase activity // traceable author statement /// 0080146 // L-cysteine desulfhydrase activity // traceable author statement 206086_x_at AF115265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF115265.1 /DEF=Homo sapiens hemochromatosis termination variant terE6 (HFE) mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis termination variant terE6 /DB_XREF=gi:11094314 /UG=Hs.20019 hemochromatosis /FL=gb:AF115265.1 gb:U60319.1 gb:NM_000410.1 AF115265 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 206087_x_at NM_000410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000410.1 /DEF=Homo sapiens hemochromatosis (HFE), mRNA. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis /DB_XREF=gi:4504376 /UG=Hs.20019 hemochromatosis /FL=gb:AF115265.1 gb:U60319.1 gb:NM_000410.1 NM_000410 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 206088_at NM_014834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014834.1 /DEF=Homo sapiens KIAA0563 gene product (KIAA0563), mRNA. /FEA=mRNA /GEN=KIAA0563 /PROD=KIAA0563 gene product /DB_XREF=gi:7662181 /UG=Hs.200597 KIAA0563 gene product /FL=gb:AB011135.1 gb:NM_014834.1 NM_014834 leucine rich repeat containing 37, member A3 LRRC37A3 374819 NM_199340 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206089_at NM_006157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006157.1 /DEF=Homo sapiens nel (chicken)-like 1 (NELL1), mRNA. /FEA=mRNA /GEN=NELL1 /PROD=nel (chicken)-like 1 /DB_XREF=gi:5453763 /UG=Hs.21602 nel (chicken)-like 1 /FL=gb:D83017.1 gb:NM_006157.1 NM_006157 NEL-like 1 (chicken) NELL1 4745 NM_001288713 /// NM_001288714 /// NM_006157 /// NM_201551 0007399 // nervous system development // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0033689 // negative regulation of osteoblast proliferation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2000599 // negative regulation of cyclin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 206090_s_at NM_018662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018662.1 /DEF=Homo sapiens disrupted in schizophrenia 1 (DISC1), mRNA. /FEA=mRNA /GEN=DISC1 /PROD=disrupted in schizophrenia 1 /DB_XREF=gi:11037064 /UG=Hs.26985 disrupted in schizophrenia 1 /FL=gb:NM_018662.1 gb:AF222980.1 NM_018662 disrupted in schizophrenia 1 /// TSNAX-DISC1 readthrough (NMD candidate) DISC1 /// TSNAX-DISC1 27185 /// 100303453 NM_001012957 /// NM_001012958 /// NM_001012959 /// NM_001039383 /// NM_001164537 /// NM_001164538 /// NM_001164539 /// NM_001164540 /// NM_001164541 /// NM_001164542 /// NM_001164544 /// NM_001164545 /// NM_001164546 /// NM_001164547 /// NM_001164548 /// NM_001164549 /// NM_001164550 /// NM_001164551 /// NM_001164552 /// NM_001164553 /// NM_001164554 /// NM_001164555 /// NM_001164556 /// NM_018662 /// NR_028393 /// NR_028394 /// NR_028395 /// NR_028396 /// NR_028397 /// NR_028398 /// NR_028399 /// NR_028400 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from mutant phenotype /// 0002052 // positive regulation of neuroblast proliferation // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from genetic interaction /// 0031929 // TOR signaling // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0090128 // regulation of synapse maturation // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // traceable author statement /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206091_at NM_002381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002381.2 /DEF=Homo sapiens matrilin 3 (MATN3) precursor, mRNA. /FEA=mRNA /GEN=MATN3 /PROD=matrilin 3 precursor /DB_XREF=gi:13518040 /UG=Hs.278461 matrilin 3 /FL=gb:NM_002381.2 NM_002381 matrilin 3 MATN3 4148 NM_002381 0001501 // skeletal system development // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206092_x_at NM_016434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016434.1 /DEF=Homo sapiens helicase-like protein NHL (LOC51750), mRNA. /FEA=mRNA /GEN=LOC51750 /PROD=helicase-like protein NHL /DB_XREF=gi:7706540 /UG=Hs.281383 helicase-like protein NHL /FL=gb:AF217795.1 gb:NM_016434.1 NM_016434 regulator of telomere elongation helicase 1 RTEL1 51750 NM_001283009 /// NM_001283010 /// NM_016434 /// NM_032957 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from sequence or structural similarity /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 206093_x_at NM_007116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007116.1 /DEF=Homo sapiens tenascin XA (TNXA), mRNA. /FEA=mRNA /GEN=TNXA /PROD=tenascin XA /DB_XREF=gi:6005907 /UG=Hs.283750 tenascin XA /FL=gb:U24488.1 gb:NM_007116.1 NM_007116 tenascin XA (pseudogene) /// tenascin XB TNXA /// TNXB 7146 /// 7148 NM_007116 /// NM_019105 /// NM_032470 /// NR_001284 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 206094_x_at NM_001072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001072.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A6 (UGT1A6), mRNA. /FEA=mRNA /GEN=UGT1A6 /PROD=UDP glycosyltransferase 1 family, polypeptideA6 /DB_XREF=gi:4507814 /UG=Hs.284239 UDP glycosyltransferase 1 family, polypeptide A6 /FL=gb:NM_001072.1 gb:J04093.1 NM_001072 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A10 /// UDP glucuronosyltransferase 1 family, polypeptide A3 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A5 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A7 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A10 /// UGT1A3 /// UGT1A4 /// UGT1A5 /// UGT1A6 /// UGT1A7 /// UGT1A8 /// UGT1A9 54575 /// 54576 /// 54577 /// 54578 /// 54579 /// 54600 /// 54657 /// 54658 /// 54659 NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_019077 /// NM_019078 /// NM_019093 /// NM_021027 /// NM_205862 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0051552 // flavone metabolic process // inferred by curator /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0001972 // retinoic acid binding // inferred by curator /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008144 // drug binding // inferred from direct assay /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred by curator /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 206095_s_at NM_006625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006625.2 /DEF=Homo sapiens TLS-associated serine-arginine protein 1 (TASR1), mRNA. /FEA=mRNA /GEN=TASR1 /PROD=TLS-associated serine-arginine protein 1 /DB_XREF=gi:12056474 /UG=Hs.288038 TLS-associated serine-arginine protein 1 /FL=gb:NM_006625.2 NM_006625 serine/arginine-rich splicing factor 10 SRSF10 10772 NM_001191005 /// NM_001191006 /// NM_001191007 /// NM_001191009 /// NM_006625 /// NM_054016 /// NR_034035 /// XM_006710298 /// XM_006710299 /// XM_006710300 /// XM_006710301 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 206096_at AI809774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI809774 /FEA=EST /DB_XREF=gi:5396340 /DB_XREF=est:wf77c11.x1 /CLONE=IMAGE:2361620 /UG=Hs.288658 zinc finger protein 35 (clone HF.10) /FL=gb:NM_003420.1 AI809774 zinc finger protein 35 ZNF35 7584 NM_003420 /// XM_005265442 /// XM_005265443 /// XM_005265444 /// XM_005265445 /// XM_005265446 /// XM_005265447 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005623 // cell // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206097_at NM_007105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007105.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 1-like antisense (SLC22A1LS), mRNA. /FEA=mRNA /GEN=SLC22A1LS /PROD=solute carrier family 22 (organic cationtransporter), member 1-like antisense /DB_XREF=gi:6005877 /UG=Hs.300076 solute carrier family 22 (organic cation transporter), member 1-like antisense /FL=gb:AF037066.1 gb:AF035407.1 gb:NM_007105.1 NM_007105 solute carrier family 22 (organic cation transporter), member 18 antisense SLC22A18AS 5003 NM_007105 206098_at NM_006626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006626.1 /DEF=Homo sapiens zinc finger protein with interaction domain (ZID), mRNA. /FEA=mRNA /GEN=ZID /PROD=zinc finger protein with interaction domain /DB_XREF=gi:5730121 /UG=Hs.3053 zinc finger protein with interaction domain /FL=gb:NM_006626.1 NM_006626 zinc finger and BTB domain containing 6 ZBTB6 10773 NM_006626 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206099_at NM_006255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006255.1 /DEF=Homo sapiens protein kinase C, eta (PRKCH), mRNA. /FEA=mRNA /GEN=PRKCH /PROD=protein kinase C, eta /DB_XREF=gi:5453971 /UG=Hs.315366 protein kinase C, eta /FL=gb:M55284.1 gb:NM_006255.1 NM_006255 protein kinase C, eta PRKCH 5583 NM_006255 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from sequence or structural similarity /// 0050861 // positive regulation of B cell receptor signaling pathway // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060252 // positive regulation of glial cell proliferation // inferred from mutant phenotype /// 0070528 // protein kinase C signaling // inferred from electronic annotation /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // traceable author statement /// 0004699 // calcium-independent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017160 // Ral GTPase binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206100_at NM_001874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001874.1 /DEF=Homo sapiens carboxypeptidase M (CPM), mRNA. /FEA=mRNA /GEN=CPM /PROD=carboxypeptidase M precursor /DB_XREF=gi:6631080 /UG=Hs.332938 carboxypeptidase M /FL=gb:NM_001874.1 NM_001874 carboxypeptidase M CPM 1368 NM_001005502 /// NM_001874 /// NM_198320 /// XM_005268653 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206101_at NM_001393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001393.1 /DEF=Homo sapiens extracellular matrix protein 2, female organ and adipocyte specific (ECM2), mRNA. /FEA=mRNA /GEN=ECM2 /PROD=extracellular matrix protein 2 /DB_XREF=gi:4557542 /UG=Hs.35094 extracellular matrix protein 2, female organ and adipocyte specific /FL=gb:AB011792.1 gb:NM_001393.1 NM_001393 extracellular matrix protein 2, female organ and adipocyte specific ECM2 1842 NM_001197295 /// NM_001197296 /// NM_001393 0006963 // positive regulation of antibacterial peptide biosynthetic process // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from electronic annotation /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0070052 // collagen V binding // inferred from electronic annotation 206102_at NM_021067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021067.1 /DEF=Homo sapiens KIAA0186 gene product (KIAA0186), mRNA. /FEA=mRNA /GEN=KIAA0186 /PROD=KIAA0186 gene product /DB_XREF=gi:10800147 /UG=Hs.36232 KIAA0186 gene product /FL=gb:NM_021067.1 gb:D80008.1 NM_021067 GINS complex subunit 1 (Psf1 homolog) GINS1 9837 NM_021067 /// XM_005260896 /// XM_006723670 /// XR_244226 /// XR_244227 0000278 // mitotic cell cycle // traceable author statement /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 206103_at NM_005052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005052.1 /DEF=Homo sapiens ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) (RAC3), mRNA. /FEA=mRNA /GEN=RAC3 /PROD=ras-related C3 botulinum toxin substrate 3 (rhofamily, small GTP binding protein Rac3) /DB_XREF=gi:4826961 /UG=Hs.45002 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) /FL=gb:AF008591.1 gb:NM_005052.1 NM_005052 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) RAC3 5881 NM_005052 /// XM_005256390 0006184 // GTP catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 206104_at NM_002202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002202.1 /DEF=Homo sapiens ISL1 transcription factor, LIMhomeodomain, (islet-1) (ISL1), mRNA. /FEA=mRNA /GEN=ISL1 /PROD=islet-1 /DB_XREF=gi:4504736 /UG=Hs.505 ISL1 transcription factor, LIMhomeodomain, (islet-1) /FL=gb:NM_002202.1 gb:U07559.1 NM_002202 ISL LIM homeobox 1 ISL1 3670 NM_002202 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from mutant phenotype /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0021520 // spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021524 // visceral motor neuron differentiation // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from sequence or structural similarity /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred by curator /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032730 // positive regulation of interleukin-1 alpha production // inferred from sequence or structural similarity /// 0032731 // positive regulation of interleukin-1 beta production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from sequence or structural similarity /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0048880 // sensory system development // inferred from sequence or structural similarity /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from electronic annotation /// 0060384 // innervation // inferred from sequence or structural similarity /// 0060413 // atrial septum morphogenesis // inferred from sequence or structural similarity /// 0060913 // cardiac cell fate determination // inferred from direct assay /// 0071385 // cellular response to glucocorticoid stimulus // inferred from sequence or structural similarity /// 0071657 // positive regulation of granulocyte colony-stimulating factor production // inferred from sequence or structural similarity /// 0090074 // negative regulation of protein homodimerization activity // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1901258 // positive regulation of macrophage colony-stimulating factor production // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from sequence or structural similarity /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206105_at NM_002025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002025.1 /DEF=Homo sapiens fragile X mental retardation 2 (FMR2), mRNA. /FEA=mRNA /GEN=FMR2 /PROD=fragile X mental retardation 2 /DB_XREF=gi:4503766 /UG=Hs.54472 fragile X mental retardation 2 /FL=gb:U48436.1 gb:NM_002025.1 NM_002025 AF4/FMR2 family, member 2 AFF2 2334 NM_001169122 /// NM_001169123 /// NM_001169124 /// NM_001169125 /// NM_001170628 /// NM_002025 0006397 // mRNA processing // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0002151 // G-quadruplex RNA binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation 206106_at AL022328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022328 /DEF=Human DNA sequence from clone RP3-402G11 on chromosome 22q13.31-13.33 Contains the MAPK12 gene for mitogen activated protein kinase 12 (SAPK3), the MAPK11 gene for mitogen activated protein kinase 11 (PRKM11), gene KIAA0315, the gene for a novel p... /FEA=mRNA_7 /DB_XREF=gi:5263010 /UG=Hs.55039 mitogen-activated protein kinase 12 /FL=gb:U66243.1 gb:NM_002969.2 AL022328 mitogen-activated protein kinase 12 MAPK12 6300 NM_002969 /// XM_003846644 /// XM_005275911 0000165 // MAPK cascade // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0042692 // muscle cell differentiation // traceable author statement /// 0045445 // myoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206107_at NM_003834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003834.1 /DEF=Homo sapiens regulator of G-protein signalling 11 (RGS11), mRNA. /FEA=mRNA /GEN=RGS11 /PROD=regulator of G-protein signalling 11 /DB_XREF=gi:4506506 /UG=Hs.65756 regulator of G-protein signalling 11 /FL=gb:AF035153.1 gb:AF035154.1 gb:NM_003834.1 NM_003834 regulator of G-protein signaling 11 RGS11 8786 NM_001286485 /// NM_001286486 /// NM_003834 /// NM_183337 /// XR_429649 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0044292 // dendrite terminus // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0031681 // G-protein beta-subunit binding // inferred from physical interaction 206108_s_at NM_006275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006275.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 6 (SFRS6), mRNA. /FEA=mRNA /GEN=SFRS6 /PROD=splicing factor, arginineserine-rich 6 /DB_XREF=gi:11225261 /UG=Hs.6891 splicing factor, arginineserine-rich 6 /FL=gb:U30883.1 gb:NM_006275.1 NM_006275 serine/arginine-rich splicing factor 6 SRSF6 6431 NM_006275 /// NR_034009 0000380 // alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010837 // regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0045617 // negative regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0061041 // regulation of wound healing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 206109_at NM_000148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000148.1 /DEF=Homo sapiens fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included) (FUT1), mRNA. /FEA=mRNA /GEN=FUT1 /PROD=fucosyltransferase 1 (galactoside2-alpha-L-fucosyltransferase, Bombay phenotype included) /DB_XREF=gi:4503804 /UG=Hs.69747 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included) /FL=gb:M35531.1 gb:NM_000148.1 NM_000148 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) FUT1 2523 NM_000148 /// XM_006723127 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // traceable author statement /// 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 206110_at NM_003536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003536.1 /DEF=Homo sapiens H3 histone family, member K (H3FK), mRNA. /FEA=mRNA /GEN=H3FK /PROD=H3 histone family, member K /DB_XREF=gi:4504294 /UG=Hs.70937 H3 histone family, member K /FL=gb:NM_003536.1 NM_003536 histone cluster 1, H3a /// histone cluster 1, H3b /// histone cluster 1, H3c /// histone cluster 1, H3d /// histone cluster 1, H3e /// histone cluster 1, H3f /// histone cluster 1, H3g /// histone cluster 1, H3h /// histone cluster 1, H3i /// histone cluster 1, H3j HIST1H3A /// HIST1H3B /// HIST1H3C /// HIST1H3D /// HIST1H3E /// HIST1H3F /// HIST1H3G /// HIST1H3H /// HIST1H3I /// HIST1H3J 8350 /// 8351 /// 8352 /// 8353 /// 8354 /// 8355 /// 8356 /// 8357 /// 8358 /// 8968 NM_003529 /// NM_003530 /// NM_003531 /// NM_003532 /// NM_003533 /// NM_003534 /// NM_003535 /// NM_003536 /// NM_003537 /// NM_021018 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206111_at NM_002934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002934.1 /DEF=Homo sapiens ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) (RNASE2), mRNA. /FEA=mRNA /GEN=RNASE2 /PROD=ribonuclease, RNase A family, 2 (liver,eosinophil-derived neurotoxin) /DB_XREF=gi:4506548 /UG=Hs.728 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) /FL=gb:M24157.1 gb:M30510.1 gb:NM_002934.1 gb:M28129.1 NM_002934 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) RNASE2 6036 NM_002934 0006401 // RNA catabolic process // traceable author statement /// 0006935 // chemotaxis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation 206112_at NM_019644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019644.1 /DEF=Homo sapiens testis-specific ankyrin motif containing protein (LOC56311), mRNA. /FEA=mRNA /GEN=LOC56311 /PROD=testis-specific ankyrin motif containingprotein /DB_XREF=gi:9790006 /UG=Hs.73073 testis-specific ankyrin motif containing protein /FL=gb:D78334.1 gb:NM_019644.1 NM_019644 ankyrin repeat domain 7 ANKRD7 56311 NM_001077708 /// NM_019644 0008584 // male gonad development // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206113_s_at NM_004162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004162.1 /DEF=Homo sapiens RAB5A, member RAS oncogene family (RAB5A), mRNA. /FEA=mRNA /GEN=RAB5A /PROD=RAB5A, member RAS oncogene family /DB_XREF=gi:4759003 /UG=Hs.73957 RAB5A, member RAS oncogene family /FL=gb:NM_004162.1 gb:M28215.1 NM_004162 RAB5A, member RAS oncogene family RAB5A 5868 NM_001292048 /// NM_004162 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 206114_at NM_004438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004438.1 /DEF=Homo sapiens EphA4 (EPHA4), mRNA. /FEA=mRNA /GEN=EPHA4 /PROD=EphA4 /DB_XREF=gi:4758279 /UG=Hs.73964 EphA4 /FL=gb:NM_004438.1 gb:L36645.1 NM_004438 EPH receptor A4 EPHA4 2043 NM_004438 /// XM_005246374 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from sequence or structural similarity /// 0008347 // glial cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021957 // corticospinal tract morphogenesis // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032317 // regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0048681 // negative regulation of axon regeneration // inferred from sequence or structural similarity /// 0048710 // regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity /// 0097156 // fasciculation of motor neuron axon // inferred from sequence or structural similarity /// 2001108 // positive regulation of Rho guanyl-nucleotide exchange factor activity // inferred from direct assay 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0097161 // DH domain binding // inferred from direct assay 206115_at NM_004430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004430.1 /DEF=Homo sapiens early growth response 3 (EGR3), mRNA. /FEA=mRNA /GEN=EGR3 /PROD=early growth response 3 /DB_XREF=gi:4758251 /UG=Hs.74088 early growth response 3 /FL=gb:NM_004430.1 NM_004430 early growth response 3 EGR3 1960 NM_001199880 /// NM_001199881 /// NM_004430 /// XM_005273425 /// XM_005273426 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007623 // circadian rhythm // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // not recorded /// 0071371 // cellular response to gonadotropin stimulus // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206116_s_at NM_000366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000366.1 /DEF=Homo sapiens tropomyosin 1 (alpha) (TPM1), mRNA. /FEA=mRNA /GEN=TPM1 /PROD=tropomyosin 1 (alpha) /DB_XREF=gi:4507646 /UG=Hs.77899 tropomyosin 1 (alpha) /FL=gb:M19713.1 gb:NM_000366.1 NM_000366 tropomyosin 1 (alpha) TPM1 7168 NM_000366 /// NM_001018004 /// NM_001018005 /// NM_001018006 /// NM_001018007 /// NM_001018008 /// NM_001018020 /// XM_005254637 /// XM_005254638 /// XM_005254639 /// XM_005254640 /// XM_005254641 /// XM_005254643 /// XM_005254644 /// XM_005254645 /// XM_005254646 /// XM_005254647 /// XM_005254648 /// XM_005254649 /// XM_005254650 /// XM_005254651 /// XM_005254652 /// XM_005254653 /// XM_006720667 /// XM_006720668 /// XM_006720669 /// XR_429470 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003065 // positive regulation of heart rate by epinephrine // inferred from sequence or structural similarity /// 0006413 // translational initiation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from sequence or structural similarity /// 0030049 // muscle filament sliding // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032059 // bleb // inferred from mutant phenotype /// 0032587 // ruffle membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 206117_at NM_000366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000366.1 /DEF=Homo sapiens tropomyosin 1 (alpha) (TPM1), mRNA. /FEA=mRNA /GEN=TPM1 /PROD=tropomyosin 1 (alpha) /DB_XREF=gi:4507646 /UG=Hs.77899 tropomyosin 1 (alpha) /FL=gb:M19713.1 gb:NM_000366.1 NM_000366 tropomyosin 1 (alpha) TPM1 7168 NM_000366 /// NM_001018004 /// NM_001018005 /// NM_001018006 /// NM_001018007 /// NM_001018008 /// NM_001018020 /// XM_005254637 /// XM_005254638 /// XM_005254639 /// XM_005254640 /// XM_005254641 /// XM_005254643 /// XM_005254644 /// XM_005254645 /// XM_005254646 /// XM_005254647 /// XM_005254648 /// XM_005254649 /// XM_005254650 /// XM_005254651 /// XM_005254652 /// XM_005254653 /// XM_006720667 /// XM_006720668 /// XM_006720669 /// XR_429470 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003065 // positive regulation of heart rate by epinephrine // inferred from sequence or structural similarity /// 0006413 // translational initiation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from sequence or structural similarity /// 0030049 // muscle filament sliding // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032059 // bleb // inferred from mutant phenotype /// 0032587 // ruffle membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 206118_at NM_003151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003151.1 /DEF=Homo sapiens signal transducer and activator of transcription 4 (STAT4), mRNA. /FEA=mRNA /GEN=STAT4 /PROD=signal transducer and activator of transcription4 /DB_XREF=gi:4507254 /UG=Hs.80642 signal transducer and activator of transcription 4 /FL=gb:L78440.1 gb:NM_003151.1 NM_003151 signal transducer and activator of transcription 4 STAT4 6775 NM_001243835 /// NM_003151 /// XM_005246817 /// XM_006712719 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206119_at NM_001713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001713.1 /DEF=Homo sapiens betaine-homocysteine methyltransferase (BHMT), mRNA. /FEA=mRNA /GEN=BHMT /PROD=betaine-homocysteine methyltransferase /DB_XREF=gi:4502406 /UG=Hs.80756 betaine-homocysteine methyltransferase /FL=gb:U50929.1 gb:NM_001713.1 NM_001713 betaine--homocysteine S-methyltransferase BHMT 635 NM_001713 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006479 // protein methylation // non-traceable author statement /// 0006577 // amino-acid betaine metabolic process // inferred from direct assay /// 0006579 // amino-acid betaine catabolic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0033477 // S-methylmethionine metabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046500 // S-adenosylmethionine metabolic process // inferred from direct assay /// 0050666 // regulation of homocysteine metabolic process // non-traceable author statement /// 0071267 // L-methionine salvage // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008898 // S-adenosylmethionine-homocysteine S-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047150 // betaine-homocysteine S-methyltransferase activity // inferred from direct assay /// 0047150 // betaine-homocysteine S-methyltransferase activity // non-traceable author statement /// 0047150 // betaine-homocysteine S-methyltransferase activity // traceable author statement /// 0061627 // S-methylmethionine-homocysteine S-methyltransferase activity // inferred from direct assay 206120_at NM_001772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001772.1 /DEF=Homo sapiens CD33 antigen (gp67) (CD33), mRNA. /FEA=mRNA /GEN=CD33 /PROD=CD33 antigen (gp67) /DB_XREF=gi:4502654 /UG=Hs.83731 CD33 antigen (gp67) /FL=gb:M23197.1 gb:NM_001772.1 NM_001772 CD33 molecule CD33 945 NM_001082618 /// NM_001177608 /// NM_001772 /// XM_005259433 /// XM_005259434 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206121_at NM_000036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000036.1 /DEF=Homo sapiens adenosine monophosphate deaminase 1 (isoform M) (AMPD1), mRNA. /FEA=mRNA /GEN=AMPD1 /PROD=adenosine monophosphate deaminase 1 (isoform M) /DB_XREF=gi:4557310 /UG=Hs.89570 adenosine monophosphate deaminase 1 (isoform M) /FL=gb:M60092.1 gb:NM_000036.1 NM_000036 adenosine monophosphate deaminase 1 AMPD1 270 NM_000036 /// NM_001172626 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006188 // IMP biosynthetic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032264 // IMP salvage // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003876 // AMP deaminase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206122_at NM_006942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006942.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 20 (SOX20), mRNA. /FEA=mRNA /GEN=SOX20 /PROD=SRY (sex determining region Y)-box 20 /DB_XREF=gi:5902105 /UG=Hs.95582 SRY (sex determining region Y)-box 20 /FL=gb:BC000985.1 gb:AB006867.1 gb:NM_006942.1 NM_006942 SRY (sex determining region Y)-box 15 SOX15 6665 NM_006942 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0014718 // positive regulation of satellite cell activation involved in skeletal muscle regeneration // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045843 // negative regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0070318 // positive regulation of G0 to G1 transition // inferred from sequence or structural similarity /// 2000288 // positive regulation of myoblast proliferation // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206123_at D50550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50550.1 /DEF=Human LLGL mRNA, complete cds. /FEA=mRNA /GEN=LLGL /DB_XREF=gi:1256170 /UG=Hs.95659 lethal giant larvae (Drosophila) homolog 1 /FL=gb:D50550.1 gb:NM_004140.1 D50550 lethal giant larvae homolog 1 (Drosophila) LLGL1 3996 NM_004140 /// XM_005256643 /// XM_005256644 0006461 // protein complex assembly // inferred from direct assay /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from sequence or structural similarity /// 0035090 // maintenance of apical/basal cell polarity // inferred from electronic annotation 0000137 // Golgi cis cisterna // inferred from sequence or structural similarity /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay 206124_s_at NM_004140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004140.1 /DEF=Homo sapiens lethal giant larvae (Drosophila) homolog 1 (LLGL1), mRNA. /FEA=mRNA /GEN=LLGL1 /PROD=lethal giant larvae (Drosophila) homolog 1 /DB_XREF=gi:4758677 /UG=Hs.95659 lethal giant larvae (Drosophila) homolog 1 /FL=gb:D50550.1 gb:NM_004140.1 NM_004140 lethal giant larvae homolog 1 (Drosophila) LLGL1 3996 NM_004140 /// XM_005256643 /// XM_005256644 0006461 // protein complex assembly // inferred from direct assay /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from sequence or structural similarity /// 0035090 // maintenance of apical/basal cell polarity // inferred from electronic annotation 0000137 // Golgi cis cisterna // inferred from sequence or structural similarity /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay 206125_s_at NM_007196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007196.1 /DEF=Homo sapiens kallikrein 8 (neuropsinovasin) (KLK8), mRNA. /FEA=mRNA /GEN=KLK8 /PROD=kallikrein 8 (neuropsinovasin) /DB_XREF=gi:6005843 /UG=Hs.104570 kallikrein 8 (neuropsinovasin) /FL=gb:AB009849.1 gb:AF095742.1 gb:NM_007196.1 gb:AB008390.2 NM_007196 kallikrein-related peptidase 8 KLK8 11202 NM_001281431 /// NM_007196 /// NM_144505 /// NM_144506 /// NM_144507 /// NR_104008 0006508 // proteolysis // inferred from electronic annotation /// 0007613 // memory // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from sequence or structural similarity /// 0009611 // response to wounding // inferred from sequence or structural similarity /// 0031642 // negative regulation of myelination // inferred from sequence or structural similarity /// 0043616 // keratinocyte proliferation // inferred from sequence or structural similarity /// 0048681 // negative regulation of axon regeneration // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050807 // regulation of synapse organization // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206126_at NM_001716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001716.1 /DEF=Homo sapiens Burkitt lymphoma receptor 1, GTP-binding protein (BLR1), mRNA. /FEA=mRNA /GEN=BLR1 /PROD=Burkitt lymphoma receptor 1, GTP-bindingprotein /DB_XREF=gi:4502414 /UG=Hs.113916 Burkitt lymphoma receptor 1, GTP-binding protein /FL=gb:NM_001716.1 NM_001716 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation 206127_at NM_005230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005230.1 /DEF=Homo sapiens ELK3, ETS-domain protein (SRF accessory protein 2) (ELK3), mRNA. /FEA=mRNA /GEN=ELK3 /PROD=ELK3 protein /DB_XREF=gi:4885202 /UG=Hs.121529 ELK3, ETS-domain protein (SRF accessory protein 2) /FL=gb:NM_005230.1 NM_005230 ELK3, ETS-domain protein (SRF accessory protein 2) ELK3 2004 NM_005230 /// XM_006719275 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0042060 // wound healing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032422 // purine-rich negative regulatory element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206128_at AI264306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI264306 /FEA=EST /DB_XREF=gi:3872509 /DB_XREF=est:qi09a02.x1 /CLONE=IMAGE:1855946 /UG=Hs.123022 adrenergic, alpha-2C-, receptor /FL=gb:J03853.1 gb:NM_000683.1 AI264306 adrenoceptor alpha 2C ADRA2C 152 NM_000683 0006112 // energy reserve metabolic process // traceable author statement /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // non-traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032811 // negative regulation of epinephrine secretion // non-traceable author statement /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0070473 // negative regulation of uterine smooth muscle contraction // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071883 // activation of MAPK activity by adrenergic receptor signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004938 // alpha2-adrenergic receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031694 // alpha-2A adrenergic receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051379 // epinephrine binding // inferred from direct assay 206129_s_at NM_000046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000046.1 /DEF=Homo sapiens arylsulfatase B (ARSB), mRNA. /FEA=mRNA /GEN=ARSB /PROD=arylsulfatase B precursor /DB_XREF=gi:4557332 /UG=Hs.1256 arylsulfatase B /FL=gb:J05225.1 gb:NM_000046.1 NM_000046 arylsulfatase B ARSB 411 NM_000046 /// NM_198709 /// XM_005248506 /// XM_006714615 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007041 // lysosomal transport // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051597 // response to methylmercury // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003943 // N-acetylgalactosamine-4-sulfatase activity // traceable author statement /// 0004065 // arylsulfatase activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206130_s_at NM_001181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001181.1 /DEF=Homo sapiens asialoglycoprotein receptor 2 (ASGR2), mRNA. /FEA=mRNA /GEN=ASGR2 /PROD=asialoglycoprotein receptor 2 /DB_XREF=gi:4502252 /UG=Hs.1259 asialoglycoprotein receptor 2 /FL=gb:M11025.1 gb:NM_001181.1 NM_001181 asialoglycoprotein receptor 2 ASGR2 433 NM_001181 /// NM_001201352 /// NM_080912 /// NM_080913 /// NM_080914 /// XM_005256645 /// XM_005256648 /// XM_006721522 /// XM_006721523 /// XM_006721524 /// XM_006721525 /// XM_006721526 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004873 // asialoglycoprotein receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 206131_at NM_001832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001832.2 /DEF=Homo sapiens colipase, pancreatic (CLPS), mRNA. /FEA=mRNA /GEN=CLPS /PROD=colipase preproprotein /DB_XREF=gi:11496883 /UG=Hs.1340 colipase, pancreatic /FL=gb:NM_001832.2 gb:J02883.1 NM_001832 colipase, pancreatic CLPS 1208 NM_001252597 /// NM_001252598 /// NM_001832 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044241 // lipid digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008047 // enzyme activator activity // inferred from electronic annotation 206132_at NM_002387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002387.1 /DEF=Homo sapiens mutated in colorectal cancers (MCC), mRNA. /FEA=mRNA /GEN=MCC /PROD=mutated in colorectal cancers /DB_XREF=gi:4505128 /UG=Hs.1345 mutated in colorectal cancers /FL=gb:M62397.1 gb:NM_002387.1 NM_002387 mutated in colorectal cancers MCC 4163 NM_001085377 /// NM_002387 /// XM_005271991 /// XM_006714617 0007165 // signal transduction // traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206133_at NM_017523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017523.1 /DEF=Homo sapiens XIAP associated factor-1 (HSXIAPAF1), mRNA. /FEA=mRNA /GEN=HSXIAPAF1 /PROD=XIAP associated factor-1 /DB_XREF=gi:8923794 /UG=Hs.139262 XIAP associated factor-1 /FL=gb:NM_017523.1 NM_017523 XIAP associated factor 1 XAF1 54739 NM_017523 /// NM_199139 /// NR_046396 /// NR_046397 /// NR_046398 /// XM_005256706 /// XM_005256707 /// XM_005256708 /// XM_006721550 /// XM_006721551 /// XM_006721552 /// XR_429816 /// XR_429817 0006915 // apoptotic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0035456 // response to interferon-beta // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206134_at NM_014479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014479.1 /DEF=Homo sapiens disintegrin protease (M12.219), mRNA. /FEA=mRNA /GEN=M12.219 /PROD=disintegrin protease /DB_XREF=gi:7657318 /UG=Hs.145296 disintegrin protease /FL=gb:NM_014479.1 NM_014479 ADAM-like, decysin 1 ADAMDEC1 27299 NM_001145271 /// NM_001145272 /// NM_014479 /// XR_428306 0006508 // proteolysis // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206135_at NM_014682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014682.1 /DEF=Homo sapiens KIAA0535 gene product (KIAA0535), mRNA. /FEA=mRNA /GEN=KIAA0535 /PROD=KIAA0535 gene product /DB_XREF=gi:7662167 /UG=Hs.151449 KIAA0535 gene product /FL=gb:AB011107.1 gb:NM_014682.1 NM_014682 suppression of tumorigenicity 18, zinc finger ST18 9705 NM_014682 /// XM_006716487 /// XM_006716488 /// XM_006716489 /// XM_006716490 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206136_at NM_003468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003468.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 5 (FZD5), mRNA. /FEA=mRNA /GEN=FZD5 /PROD=frizzled 5 /DB_XREF=gi:4503828 /UG=Hs.152251 frizzled (Drosophila) homolog 5 /FL=gb:U43318.1 gb:NM_003468.1 NM_003468 frizzled class receptor 5 FZD5 7855 NM_003468 /// NM_030804 0000578 // embryonic axis specification // inferred from direct assay /// 0001525 // angiogenesis // not recorded /// 0001944 // vasculature development // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0008595 // anterior/posterior axis specification, embryo // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031076 // embryonic camera-type eye development // not recorded /// 0031077 // post-embryonic camera-type eye development // not recorded /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // not recorded /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0060061 // Spemann organizer formation // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060561 // apoptotic process involved in morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // not recorded /// 0071219 // cellular response to molecule of bacterial origin // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0042995 // cell projection // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0042813 // Wnt-activated receptor activity // inferred by curator 206137_at NM_014677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014677.1 /DEF=Homo sapiens KIAA0751 gene product (KIAA0751), mRNA. /FEA=mRNA /GEN=KIAA0751 /PROD=KIAA0751 gene product /DB_XREF=gi:7662285 /UG=Hs.153610 KIAA0751 gene product /FL=gb:AB018294.1 gb:NM_014677.1 NM_014677 regulating synaptic membrane exocytosis 2 RIMS2 9699 NM_001100117 /// NM_001282881 /// NM_001282882 /// NM_014677 /// XM_005251106 /// XM_005251107 /// XM_005251108 /// XM_006716690 /// XM_006716691 /// XM_006716692 /// XM_006716693 /// XM_006716694 /// XM_006716695 /// XM_006716696 /// XM_006716697 /// XM_006716698 /// XM_006716699 0006886 // intracellular protein transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206138_s_at NM_002651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002651.1 /DEF=Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta polypeptide (PIK4CB), mRNA. /FEA=mRNA /GEN=PIK4CB /PROD=phosphatidylinositol 4-kinase, catalytic, betapolypeptide /DB_XREF=gi:4505808 /UG=Hs.154846 phosphatidylinositol 4-kinase, catalytic, beta polypeptide /FL=gb:AB005910.1 gb:NM_002651.1 NM_002651 phosphatidylinositol 4-kinase, catalytic, beta PI4KB 5298 NM_001198773 /// NM_001198774 /// NM_001198775 /// NM_002651 /// XM_005245261 /// XM_005245262 /// XM_005245263 /// XM_005245264 /// XM_005245265 /// XM_006711385 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 206139_at NM_002651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002651.1 /DEF=Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta polypeptide (PIK4CB), mRNA. /FEA=mRNA /GEN=PIK4CB /PROD=phosphatidylinositol 4-kinase, catalytic, betapolypeptide /DB_XREF=gi:4505808 /UG=Hs.154846 phosphatidylinositol 4-kinase, catalytic, beta polypeptide /FL=gb:AB005910.1 gb:NM_002651.1 NM_002651 phosphatidylinositol 4-kinase, catalytic, beta PI4KB 5298 NM_001198773 /// NM_001198774 /// NM_001198775 /// NM_002651 /// XM_005245261 /// XM_005245262 /// XM_005245263 /// XM_005245264 /// XM_005245265 /// XM_006711385 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 206140_at NM_004789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004789.1 /DEF=Homo sapiens LIM homeobox protein 2 (LHX2), mRNA. /FEA=mRNA /GEN=LHX2 /PROD=LIM homeobox protein 2 /DB_XREF=gi:4758673 /UG=Hs.1569 LIM homeobox protein 2 /FL=gb:AF124735.1 gb:NM_004789.1 NM_004789 LIM homeobox 2 LHX2 9355 NM_004789 /// XM_006717323 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021978 // telencephalon regionalization // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206141_at NM_014484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014484.1 /DEF=Homo sapiens molybdopterin synthase sulfurylase (MOCS3), mRNA. /FEA=mRNA /GEN=MOCS3 /PROD=molybdopterin synthase sulfurylase /DB_XREF=gi:7657338 /UG=Hs.159410 molybdopterin synthase sulfurylase /FL=gb:AF102544.1 gb:NM_014484.1 NM_014484 molybdenum cofactor synthesis 3 MOCS3 27304 NM_014484 0002098 // tRNA wobble uridine modification // inferred from direct assay /// 0002143 // tRNA wobble position uridine thiolation // not recorded /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018117 // protein adenylylation // not recorded /// 0018192 // enzyme active site formation via L-cysteine persulfide // inferred from direct assay /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0032447 // protein urmylation // not recorded /// 0034227 // tRNA thio-modification // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004792 // thiosulfate sulfurtransferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from direct assay /// 0016783 // sulfurtransferase activity // inferred from direct assay /// 0016783 // sulfurtransferase activity // traceable author statement /// 0042292 // URM1 activating enzyme activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061604 // molybdopterin-synthase sulfurtransferase activity // inferred from electronic annotation /// 0061605 // molybdopterin-synthase adenylyltransferase activity // inferred from electronic annotation /// 0070733 // protein adenylyltransferase activity // not recorded 206142_at NM_003436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003436.1 /DEF=Homo sapiens zinc finger protein 135 (clone pHZ-17) (ZNF135), mRNA. /FEA=mRNA /GEN=ZNF135 /PROD=zinc finger protein 135 (clone pHZ-17) /DB_XREF=gi:4507984 /UG=Hs.159582 zinc finger protein 135 (clone pHZ-17) /FL=gb:NM_003436.1 gb:U09413.1 NM_003436 zinc finger protein 135 ZNF135 7694 NM_001164527 /// NM_001164529 /// NM_001164530 /// NM_001289401 /// NM_001289402 /// NM_003436 /// NM_007134 /// XM_005259211 /// XM_006723362 /// XM_006723363 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206143_at NM_000111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000111.1 /DEF=Homo sapiens solute carrier family 26, member 3 (SLC26A3), mRNA. /FEA=mRNA /GEN=SLC26A3 /PROD=down-regulated in adenoma protein /DB_XREF=gi:4557534 /UG=Hs.1650 solute carrier family 26, member 3 /FL=gb:L02785.1 gb:NM_000111.1 NM_000111 solute carrier family 26 (anion exchanger), member 3 SLC26A3 1811 NM_000111 /// XM_006715873 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from sequence or structural similarity /// 0007588 // excretion // traceable author statement /// 0008272 // sulfate transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0097225 // sperm midpiece // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 206144_at NM_004742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004742.1 /DEF=Homo sapiens BAI1-associated protein 1 (BAIAP1), mRNA. /FEA=mRNA /GEN=BAIAP1 /PROD=BAI1-associated protein 1 /DB_XREF=gi:9257194 /UG=Hs.169441 BAI1-associated protein 1 /FL=gb:AB010894.1 gb:NM_004742.1 NM_004742 membrane associated guanylate kinase, WW and PDZ domain containing 1 MAGI1 9223 NM_001033057 /// NM_004742 /// NM_015520 /// XM_005265563 /// XM_005265564 /// XM_005265565 /// XM_005265566 /// XM_005265568 /// XM_005265570 /// XM_005265571 /// XM_005265574 /// XM_006713407 /// XM_006713408 /// XM_006713409 /// XM_006713410 /// XM_006713411 /// XM_006713412 /// XM_006713413 /// XM_006713414 0006461 // protein complex assembly // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0070997 // neuron death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0051393 // alpha-actinin binding // inferred from physical interaction 206145_at NM_000324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000324.1 /DEF=Homo sapiens Rhesus blood group-associated glycoprotein (RHAG), mRNA. /FEA=mRNA /GEN=RHAG /PROD=Rhesus blood group-associated glycoprotein /DB_XREF=gi:4506522 /UG=Hs.169536 Rhesus blood group-associated glycoprotein /FL=gb:AF031548.1 gb:NM_000324.1 gb:AF178841.1 gb:AF187847.1 gb:AF179682.1 gb:AF179684.1 NM_000324 Rh-associated glycoprotein RHAG 6005 NM_000324 0006810 // transport // inferred from electronic annotation /// 0006873 // cellular ion homeostasis // inferred from direct assay /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from genetic interaction /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from genetic interaction 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0008519 // ammonium transmembrane transporter activity // inferred from genetic interaction /// 0030506 // ankyrin binding // inferred from physical interaction 206146_s_at AF178841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF178841.1 /DEF=Homo sapiens Rh-null regulator protein mRNA, complete cds. /FEA=mRNA /PROD=Rh-null regulator protein /DB_XREF=gi:5853261 /UG=Hs.169536 Rhesus blood group-associated glycoprotein /FL=gb:AF031548.1 gb:NM_000324.1 gb:AF178841.1 gb:AF187847.1 gb:AF179682.1 gb:AF179684.1 AF178841 Rh-associated glycoprotein RHAG 6005 NM_000324 0006810 // transport // inferred from electronic annotation /// 0006873 // cellular ion homeostasis // inferred from direct assay /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from genetic interaction /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from genetic interaction 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0008519 // ammonium transmembrane transporter activity // inferred from genetic interaction /// 0030506 // ankyrin binding // inferred from physical interaction 206147_x_at NM_006089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006089.1 /DEF=Homo sapiens sex comb on midleg (Drosophila)-like 2 (SCML2), mRNA. /FEA=mRNA /GEN=SCML2 /PROD=sex comb on midleg (Drosophila)-like 2 /DB_XREF=gi:5174668 /UG=Hs.171558 sex comb on midleg (Drosophila)-like 2 /FL=gb:NM_006089.1 NM_006089 sex comb on midleg-like 2 (Drosophila) SCML2 10389 NM_006089 /// NR_033717 /// XM_006724457 /// XM_006724458 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206148_at NM_002183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002183.1 /DEF=Homo sapiens interleukin 3 receptor, alpha (low affinity) (IL3RA), mRNA. /FEA=mRNA /GEN=IL3RA /PROD=interleukin 3 receptor, alpha (low affinity) /DB_XREF=gi:13324709 /UG=Hs.172689 interleukin 3 receptor, alpha (low affinity) /FL=gb:NM_002183.1 gb:M74782.1 NM_002183 interleukin 3 receptor, alpha (low affinity) IL3RA 3563 NM_001267713 /// NM_002183 /// XM_005274431 /// XM_005274432 /// XM_005274780 /// XM_005274781 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0036016 // cellular response to interleukin-3 // traceable author statement /// 0038156 // interleukin-3-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004912 // interleukin-3 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206149_at NM_022097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022097.1 /DEF=Homo sapiens hepatocellular carcinoma antigen gene 520 (LOC63928), mRNA. /FEA=mRNA /GEN=LOC63928 /PROD=hepatocellular carcinoma antigen gene 520 /DB_XREF=gi:11545810 /UG=Hs.178589 hepatocellular carcinoma antigen gene 520 /FL=gb:AF146019.1 gb:NM_022097.1 NM_022097 calcineurin-like EF-hand protein 2 CHP2 63928 NM_022097 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010922 // positive regulation of phosphatase activity // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206150_at NM_001242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001242.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 7 (TNFRSF7), mRNA. /FEA=mRNA /GEN=TNFRSF7 /PROD=CD27 antigen /DB_XREF=gi:4507586 /UG=Hs.180841 tumor necrosis factor receptor superfamily, member 7 /FL=gb:M63928.1 gb:NM_001242.1 NM_001242 CD27 molecule CD27 939 NM_001242 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008588 // release of cytoplasmic sequestered NF-kappaB // non-traceable author statement /// 0016064 // immunoglobulin mediated immune response // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // non-traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from sequence or structural similarity /// 0070233 // negative regulation of T cell apoptotic process // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay 206151_x_at NM_007352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007352.1 /DEF=Homo sapiens elastase 3B (ELA3B), mRNA. /FEA=mRNA /GEN=ELA3B /PROD=elastase 3B /DB_XREF=gi:6679624 /UG=Hs.183864 elastase 3B /FL=gb:BC005216.1 gb:M18692.1 gb:NM_007352.1 NM_007352 chymotrypsin-like elastase family, member 3B CELA3B 23436 NM_007352 0006508 // proteolysis // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206152_at NM_014770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014770.1 /DEF=Homo sapiens KIAA0167 gene product (KIAA0167), mRNA. /FEA=mRNA /GEN=KIAA0167 /PROD=KIAA0167 gene product /DB_XREF=gi:7661961 /UG=Hs.184884 KIAA0167 gene product /FL=gb:D79989.1 gb:NM_014770.1 NM_014770 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 AGAP2 116986 NM_001122772 /// NM_014770 /// XM_005268625 /// XM_005268626 /// XR_245891 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206153_at NM_021187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021187.1 /DEF=Homo sapiens cytochrome P450, subfamily IVF, polypeptide 11 (CYP4F11), mRNA. /FEA=mRNA /GEN=CYP4F11 /PROD=cytochrome P450, subfamily IVF, polypeptide 11 /DB_XREF=gi:10863992 /UG=Hs.187393 cytochrome P450, subfamily IVF, polypeptide 11 /FL=gb:AF236085.1 gb:NM_021187.1 NM_021187 cytochrome P450, family 4, subfamily F, polypeptide 11 CYP4F11 57834 NM_001128932 /// NM_021187 0006805 // xenobiotic metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 206154_at NM_000326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000326.1 /DEF=Homo sapiens retinaldehyde-binding protein 1 (RLBP1), mRNA. /FEA=mRNA /GEN=RLBP1 /PROD=retinaldehyde-binding protein 1 /DB_XREF=gi:4506540 /UG=Hs.1933 retinaldehyde-binding protein 1 /FL=gb:BC004199.1 gb:J04213.1 gb:NM_000326.1 NM_000326 retinaldehyde binding protein 1 RLBP1 6017 NM_000326 0001523 // retinoid metabolic process // traceable author statement /// 0006776 // vitamin A metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005502 // 11-cis retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 206155_at NM_000392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000392.1 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 2 (ABCC2), mRNA. /FEA=mRNA /GEN=ABCC2 /PROD=ATP-binding cassette, sub-family C (CFTRMRP),member 2 /DB_XREF=gi:4557480 /UG=Hs.193852 ATP-binding cassette, sub-family C (CFTRMRP), member 2 /FL=gb:U49248.1 gb:U63970.1 gb:NM_000392.1 NM_000392 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 ABCC2 1244 NM_000392 /// XM_006717630 /// XM_006717631 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006855 // drug transmembrane transport // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0015732 // prostaglandin transport // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070327 // thyroid hormone transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0046581 // intercellular canaliculus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 206156_at NM_005268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005268.1 /DEF=Homo sapiens gap junction protein, beta 5 (connexin 31.1) (GJB5), mRNA. /FEA=mRNA /GEN=GJB5 /PROD=gap junction protein, beta 5 (connexin 31.1) /DB_XREF=gi:10835078 /UG=Hs.198249 gap junction protein, beta 5 (connexin 31.1) /FL=gb:NM_005268.1 gb:BC004379.1 gb:AF052693.1 NM_005268 gap junction protein, beta 5, 31.1kDa GJB5 2709 NM_005268 /// XM_005270751 0007154 // cell communication // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 206157_at NM_002852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002852.1 /DEF=Homo sapiens pentaxin-related gene, rapidly induced by IL-1 beta (PTX3), mRNA. /FEA=mRNA /GEN=PTX3 /PROD=pentaxin-related gene, rapidly induced by IL-1beta /DB_XREF=gi:4506332 /UG=Hs.2050 pentaxin-related gene, rapidly induced by IL-1 beta /FL=gb:M31166.1 gb:NM_002852.1 NM_002852 pentraxin 3, long PTX3 5806 NM_002852 0001878 // response to yeast // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0008228 // opsonization // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 1903016 // negative regulation of exo-alpha-sialidase activity // inferred from direct assay /// 1903019 // negative regulation of glycoprotein metabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0001872 // (1->3)-beta-D-glucan binding // inferred from electronic annotation /// 0046790 // virion binding // inferred from direct assay 206158_s_at NM_003418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003418.1 /DEF=Homo sapiens zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) (ZNF9), mRNA. /FEA=mRNA /GEN=ZNF9 /PROD=zinc finger protein 9 (a cellular retroviralnucleic acid binding protein) /DB_XREF=gi:4827070 /UG=Hs.2110 zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) /FL=gb:NM_003418.1 gb:M28372.1 NM_003418 CCHC-type zinc finger, nucleic acid binding protein CNBP 7555 NM_001127192 /// NM_001127193 /// NM_001127194 /// NM_001127195 /// NM_001127196 /// NM_003418 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206159_at NM_004962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004962.2 /DEF=Homo sapiens growth differentiation factor 10 (GDF10), mRNA. /FEA=mRNA /GEN=GDF10 /PROD=growth differentiation factor 10 precursor /DB_XREF=gi:11641417 /UG=Hs.2171 growth differentiation factor 10 /FL=gb:NM_004962.2 NM_004962 growth differentiation factor 10 GDF10 2662 NM_004962 /// XM_006717762 0001501 // skeletal system development // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206160_at NM_006789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006789.1 /DEF=Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 (APOBEC2), mRNA. /FEA=mRNA /GEN=APOBEC2 /PROD=apolipoprotein B mRNA editing enzyme, catalyticpolypeptide-like 2 /DB_XREF=gi:5802977 /UG=Hs.227457 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 /FL=gb:AF161698.1 gb:NM_006789.1 NM_006789 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 APOBEC2 10930 NM_006789 0006397 // mRNA processing // inferred from electronic annotation /// 0009972 // cytidine deamination // traceable author statement /// 0016556 // mRNA modification // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206161_s_at AI659957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659957 /FEA=EST /DB_XREF=gi:4763527 /DB_XREF=est:we70h05.x1 /CLONE=IMAGE:2346489 /UG=Hs.23179 synaptotagmin V /FL=gb:NM_003180.1 AI659957 synaptotagmin V SYT5 6861 NM_003180 /// XM_006723338 /// XM_006723339 /// XM_006723340 /// XM_006723341 /// XM_006723342 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206162_x_at NM_003180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003180.1 /DEF=Homo sapiens synaptotagmin 5 (SYT5), mRNA. /FEA=mRNA /GEN=SYT5 /PROD=synaptotagmin 5 /DB_XREF=gi:4507336 /UG=Hs.23179 synaptotagmin V /FL=gb:NM_003180.1 NM_003180 synaptotagmin V SYT5 6861 NM_003180 /// XM_006723338 /// XM_006723339 /// XM_006723340 /// XM_006723341 /// XM_006723342 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206163_at NM_005584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005584.1 /DEF=Homo sapiens mab-21 (C. elegans)-like 1 (MAB21L1), mRNA. /FEA=mRNA /GEN=MAB21L1 /PROD=mab-21 (C. elegans)-like 1 /DB_XREF=gi:5031896 /UG=Hs.239506 mab-21 (C. elegans)-like 1 /FL=gb:U38810.1 gb:NM_005584.1 NM_005584 mab-21-like 1 (C. elegans) /// microRNA 548f-5 MAB21L1 /// MIR548F5 4081 /// 100302239 NM_005584 /// NR_031646 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 206164_at NM_006536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006536.2 /DEF=Homo sapiens chloride channel, calcium activated, family member 2 (CLCA2), mRNA. /FEA=mRNA /GEN=CLCA2 /PROD=calcium activated chloride channel 2 precursor /DB_XREF=gi:12025665 /UG=Hs.241551 chloride channel, calcium activated, family member 2 /FL=gb:NM_006536.2 gb:AB026833.1 gb:AF043977.1 gb:AF127980.1 NM_006536 chloride channel accessory 2 CLCA2 9635 NM_006536 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005254 // chloride channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation 206165_s_at NM_006536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006536.2 /DEF=Homo sapiens chloride channel, calcium activated, family member 2 (CLCA2), mRNA. /FEA=mRNA /GEN=CLCA2 /PROD=calcium activated chloride channel 2 precursor /DB_XREF=gi:12025665 /UG=Hs.241551 chloride channel, calcium activated, family member 2 /FL=gb:NM_006536.2 gb:AB026833.1 gb:AF043977.1 gb:AF127980.1 NM_006536 chloride channel accessory 2 CLCA2 9635 NM_006536 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005254 // chloride channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation 206166_s_at AF043977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043977.1 /DEF=Homo sapiens calcium-activated chloride channel-2 (hCLCA2) mRNA, complete cds. /FEA=mRNA /GEN=hCLCA2 /PROD=calcium-activated chloride channel-2 /DB_XREF=gi:5138899 /UG=Hs.241551 chloride channel, calcium activated, family member 2 /FL=gb:NM_006536.2 gb:AB026833.1 gb:AF043977.1 gb:AF127980.1 AF043977 chloride channel accessory 2 CLCA2 9635 NM_006536 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005254 // chloride channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation 206167_s_at NM_001174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001174.2 /DEF=Homo sapiens Rho GTPase activating protein 6 (ARHGAP6), transcript variant 2, mRNA. /FEA=mRNA /GEN=ARHGAP6 /PROD=Rho GTPase activating protein 6 isoform 2 /DB_XREF=gi:7382476 /UG=Hs.250830 Rho GTPase activating protein 6 /FL=gb:AF022212.2 gb:NM_001174.2 NM_001174 Rho GTPase activating protein 6 ARHGAP6 395 NM_001174 /// NM_001287242 /// NM_006125 /// NM_013422 /// NM_013423 /// NM_013427 /// NR_109776 /// XM_005274505 /// XM_005274506 /// XM_005274507 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from direct assay /// 0030041 // actin filament polymerization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 206168_at NM_025013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_025013.1 /DEF=Homo sapiens KIAA1031 protein (KIAA1031), mRNA. /FEA=mRNA /GEN=KIAA1031 /PROD=hypothetical protein FLJ13787 /DB_XREF=gi:13430879 /UG=Hs.25347 KIAA1031 protein /FL=gb:NM_025013.1 NM_025013 zinc finger CCCH-type containing 7B ZC3H7B 23264 NM_017590 0016032 // viral process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206169_x_at NM_025013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025013.1 /DEF=Homo sapiens KIAA1031 protein (KIAA1031), mRNA. /FEA=mRNA /GEN=KIAA1031 /PROD=hypothetical protein FLJ13787 /DB_XREF=gi:13430879 /UG=Hs.25347 KIAA1031 protein /FL=gb:NM_025013.1 NM_025013 zinc finger CCCH-type containing 7B ZC3H7B 23264 NM_017590 0016032 // viral process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206170_at NM_000024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000024.2 /DEF=Homo sapiens adrenergic, beta-2-, receptor, surface (ADRB2), mRNA. /FEA=mRNA /GEN=ADRB2 /PROD=adrenergic, beta-2-, receptor, surface /DB_XREF=gi:13162366 /UG=Hs.2551 adrenergic, beta-2-, receptor, surface /FL=gb:NM_000024.2 gb:M15169.1 NM_000024 adrenoceptor beta 2, surface ADRB2 154 NM_000024 0001993 // regulation of systemic arterial blood pressure by norepinephrine-epinephrine // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0002025 // vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0002032 // desensitization of G-protein coupled receptor protein signaling pathway by arrestin // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0008333 // endosome to lysosome transport // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from mutant phenotype /// 0031649 // heat generation // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045453 // bone resorption // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from direct assay /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004941 // beta2-adrenergic receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051380 // norepinephrine binding // inferred from direct assay 206171_at NM_000677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000677.2 /DEF=Homo sapiens adenosine A3 receptor (ADORA3), mRNA. /FEA=mRNA /GEN=ADORA3 /PROD=adenosine A3 receptor /DB_XREF=gi:6031156 /UG=Hs.258 adenosine A3 receptor /FL=gb:L20463.1 gb:L22607.1 gb:NM_000677.2 NM_000677 adenosine A3 receptor ADORA3 140 NM_000677 /// NM_001081976 /// NM_020683 /// XM_005270485 /// XM_005270486 /// XM_005270489 /// XM_005270490 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0070257 // positive regulation of mucus secretion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation 0001609 // G-protein coupled adenosine receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 206172_at NM_000640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000640.1 /DEF=Homo sapiens interleukin 13 receptor, alpha 2 (IL13RA2), mRNA. /FEA=mRNA /GEN=IL13RA2 /PROD=interleukin 13 receptor, alpha 2 /DB_XREF=gi:10834991 /UG=Hs.25954 interleukin 13 receptor, alpha 2 /FL=gb:NM_000640.1 gb:U70981.1 NM_000640 interleukin 13 receptor, alpha 2 IL13RA2 3598 NM_000640 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004896 // cytokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206173_x_at NM_002041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002041.2 /DEF=Homo sapiens GA-binding protein transcription factor, beta subunit 2 (47kD) (GABPB2), transcript variant gamma, mRNA. /FEA=mRNA /GEN=GABPB2 /PROD=GA-binding protein transcription factor, betasubunit 2 (47kD), isoform gamma 1 /DB_XREF=gi:8051596 /UG=Hs.278238 GA-binding protein transcription factor, beta subunit 2 (47kD) /FL=gb:U13047.1 gb:NM_002041.2 NM_002041 GA binding protein transcription factor, beta subunit 1 GABPB1 2553 NM_002041 /// NM_005254 /// NM_016654 /// NM_016655 /// NM_181427 /// XM_005254273 /// XM_005254274 /// XM_006720455 /// XM_006720456 /// XM_006720457 /// XM_006720458 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 206174_s_at NM_002721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002721.2 /DEF=Homo sapiens protein phosphatase 6, catalytic subunit (PPP6C), mRNA. /FEA=mRNA /GEN=PPP6C /PROD=protein phosphatase 6, catalytic subunit /DB_XREF=gi:5729987 /UG=Hs.279563 protein phosphatase 6, catalytic subunit /FL=gb:NM_002721.2 NM_002721 protein phosphatase 6, catalytic subunit PPP6C 5537 NM_001123355 /// NM_001123369 /// NM_002721 /// XM_006717175 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206175_x_at NM_013360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013360.1 /DEF=Homo sapiens zinc finger protein 222 (ZNF222), mRNA. /FEA=mRNA /GEN=ZNF222 /PROD=zinc finger protein 222 /DB_XREF=gi:7019586 /UG=Hs.279840 zinc finger protein 222 /FL=gb:AF187988.1 gb:NM_013360.1 NM_013360 zinc finger protein 222 ZNF222 7673 NM_001129996 /// NM_013360 /// XM_005259208 /// XM_005259209 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206176_at NM_001718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001718.2 /DEF=Homo sapiens bone morphogenetic protein 6 (BMP6), mRNA. /FEA=mRNA /GEN=BMP6 /PROD=bone morphogenetic protein 6 precursor /DB_XREF=gi:4809281 /UG=Hs.285671 bone morphogenetic protein 6 /FL=gb:M60315.1 gb:NM_001718.2 NM_001718 bone morphogenetic protein 6 BMP6 654 NM_001718 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030539 // male genitalia development // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032349 // positive regulation of aldosterone biosynthetic process // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050714 // positive regulation of protein secretion // non-traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 2000105 // positive regulation of DNA-dependent DNA replication // non-traceable author statement /// 2000860 // positive regulation of aldosterone secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from physical interaction 206177_s_at NM_000045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000045.2 /DEF=Homo sapiens arginase, liver (ARG1), mRNA. /FEA=mRNA /GEN=ARG1 /PROD=arginase, type I /DB_XREF=gi:10947138 /UG=Hs.289057 arginase, liver /FL=gb:NM_000045.2 gb:M14502.1 NM_000045 arginase 1 ARG1 383 NM_000045 /// NM_001244438 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010963 // regulation of L-arginine import // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004053 // arginase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206178_at NM_000929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000929.1 /DEF=Homo sapiens phospholipase A2, group V (PLA2G5), mRNA. /FEA=mRNA /GEN=PLA2G5 /PROD=phospholipase A2, group V /DB_XREF=gi:4505852 /UG=Hs.290 phospholipase A2, group V /FL=gb:NM_000929.1 gb:U03090.1 NM_000929 phospholipase A2, group V PLA2G5 5322 NM_000929 /// XM_005245891 /// XM_005245892 /// XM_005245893 /// XM_005245895 /// XM_005245896 /// XM_006710691 /// XM_006710692 /// XM_006710693 /// XM_006710694 /// XM_006710695 /// XM_006710696 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006663 // platelet activating factor biosynthetic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from electronic annotation 206179_s_at NM_007030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007030.1 /DEF=Homo sapiens brain-specific protein p25 alpha (p25), mRNA. /FEA=mRNA /GEN=p25 /PROD=brain-specific protein p25 alpha /DB_XREF=gi:5902017 /UG=Hs.29353 brain-specific protein p25 alpha /FL=gb:AB017016.1 gb:NM_007030.1 NM_007030 tubulin polymerization promoting protein TPPP 11076 NM_007030 /// XM_005248237 0001578 // microtubule bundle formation // inferred from direct assay /// 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0031334 // positive regulation of protein complex assembly // inferred from sequence or structural similarity /// 0032273 // positive regulation of protein polymerization // inferred from direct assay /// 0046785 // microtubule polymerization // inferred from direct assay /// 0046785 // microtubule polymerization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015631 // tubulin binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from sequence or structural similarity 206180_x_at NM_023931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023931.1 /DEF=Homo sapiens hypothetical protein MGC2474 (MGC2474), mRNA. /FEA=mRNA /GEN=MGC2474 /PROD=hypothetical protein MGC2474 /DB_XREF=gi:13027593 /UG=Hs.324709 hypothetical protein MGC2474 /FL=gb:BC001361.1 gb:NM_023931.1 NM_023931 zinc finger protein 747 ZNF747 65988 NM_023931 /// XM_005255509 /// XM_005255510 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206181_at NM_003037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003037.1 /DEF=Homo sapiens signaling lymphocytic activation molecule (SLAM), mRNA. /FEA=mRNA /GEN=SLAM /PROD=signaling lymphocytic activation molecule /DB_XREF=gi:4506968 /UG=Hs.32970 signaling lymphocytic activation molecule /FL=gb:NM_003037.1 gb:U33017.1 NM_003037 signaling lymphocytic activation molecule family member 1 SLAMF1 6504 NM_003037 /// NR_104399 /// NR_104400 /// NR_104401 /// XM_005245456 /// XM_005245457 0007165 // signal transduction // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0046649 // lymphocyte activation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206182_at NM_003435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003435.1 /DEF=Homo sapiens zinc finger protein 134 (clone pHZ-15) (ZNF134), mRNA. /FEA=mRNA /GEN=ZNF134 /PROD=zinc finger protein 134 (clone pHZ-15) /DB_XREF=gi:4507982 /UG=Hs.357 zinc finger protein 134 (clone pHZ-15) /FL=gb:NM_003435.1 gb:U09412.1 NM_003435 zinc finger protein 134 ZNF134 7693 NM_003435 /// XM_006726788 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206183_s_at NM_014606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014606.1 /DEF=Homo sapiens hect domain and RLD 3 (HERC3), mRNA. /FEA=mRNA /GEN=HERC3 /PROD=hect domain and RLD 3 /DB_XREF=gi:7657151 /UG=Hs.35804 hect domain and RLD 3 /FL=gb:D25215.1 gb:NM_014606.1 NM_014606 HECT and RLD domain containing E3 ubiquitin protein ligase 3 /// uncharacterized LOC101929134 HERC3 /// LOC101929134 8916 /// 101929134 NM_001271602 /// NM_014606 /// XM_005263327 /// XM_005263328 /// XM_005263329 /// XM_005263330 /// XM_005263331 /// XM_005263332 /// XM_006714405 /// XR_244671 /// XR_249623 /// XR_251610 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 206184_at NM_005207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005207.1 /DEF=Homo sapiens v-crk avian sarcoma virus CT10 oncogene homolog-like (CRKL), mRNA. /FEA=mRNA /GEN=CRKL /PROD=v-crk avian sarcoma virus CT10 oncogenehomolog-like /DB_XREF=gi:4885152 /UG=Hs.37078 v-crk avian sarcoma virus CT10 oncogene homolog-like /FL=gb:NM_005207.1 NM_005207 v-crk avian sarcoma virus CT10 oncogene homolog-like CRKL 1399 NM_005207 0000186 // activation of MAPKK activity // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007254 // JNK cascade // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048538 // thymus development // inferred from electronic annotation /// 0060017 // parathyroid gland development // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 206185_at NM_001887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001887.1 /DEF=Homo sapiens crystallin, beta B1 (CRYBB1), mRNA. /FEA=mRNA /GEN=CRYBB1 /PROD=crystallin, beta B1 /DB_XREF=gi:4503060 /UG=Hs.37135 crystallin, beta B1 /FL=gb:U35340.1 gb:NM_001887.1 NM_001887 crystallin, beta B1 CRYBB1 1414 NM_001887 0007601 // visual perception // traceable author statement 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206186_at NM_001932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001932.1 /DEF=Homo sapiens membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (MPP3), mRNA. /FEA=mRNA /GEN=MPP3 /PROD=palmitoylated membrane protein 3 /DB_XREF=gi:4505238 /UG=Hs.37144 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) /FL=gb:U37707.1 gb:NM_001932.1 NM_001932 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) MPP3 4356 NM_001932 /// NR_003562 /// XM_006721915 /// XM_006721916 /// XM_006721917 /// XM_006721918 /// XM_006721919 /// XR_429893 /// XR_429894 0007165 // signal transduction // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 206187_at NM_000960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000960.1 /DEF=Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), mRNA. /FEA=mRNA /GEN=PTGIR /PROD=prostaglandin I2 (prostacyclin) receptor (IP) /DB_XREF=gi:4506262 /UG=Hs.393 prostaglandin I2 (prostacyclin) receptor (IP) /FL=gb:NM_000960.1 gb:D25418.1 gb:L29016.1 gb:D29634.1 NM_000960 prostaglandin I2 (prostacyclin) receptor (IP) PTGIR 5739 NM_000960 /// XM_005259093 /// XM_005259095 /// XR_243945 /// XR_430206 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007267 // cell-cell signaling // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement 206188_at NM_014789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014789.1 /DEF=Homo sapiens KIAA0628 gene product (KIAA0628), mRNA. /FEA=mRNA /GEN=KIAA0628 /PROD=KIAA0628 gene product /DB_XREF=gi:7662213 /UG=Hs.43133 KIAA0628 gene product /FL=gb:AB014528.1 gb:NM_014789.1 NM_014789 zinc finger protein 623 ZNF623 9831 NM_001082480 /// NM_001261843 /// NM_014789 /// XM_006716708 /// XM_006725095 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 206189_at NM_003728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003728.1 /DEF=Homo sapiens unc5 (C.elegans homolog) c (UNC5C), mRNA. /FEA=mRNA /GEN=UNC5C /PROD=unc5 (C.elegans homolog) c /DB_XREF=gi:4507836 /UG=Hs.44553 unc5 (C.elegans homolog) c /FL=gb:AF055634.1 gb:NM_003728.1 NM_003728 unc-5 homolog C (C. elegans) UNC5C 8633 NM_003728 /// XM_005263321 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0033564 // anterior/posterior axon guidance // inferred from electronic annotation /// 0038007 // netrin-activated signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005042 // netrin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206190_at NM_005291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005291.1 /DEF=Homo sapiens G protein-coupled receptor 17 (GPR17), mRNA. /FEA=mRNA /GEN=GPR17 /PROD=G protein-coupled receptor 17 /DB_XREF=gi:4885300 /UG=Hs.46453 G protein-coupled receptor 17 /FL=gb:NM_005291.1 NM_005291 G protein-coupled receptor 17 GPR17 2840 NM_001161415 /// NM_001161416 /// NM_001161417 /// NM_005291 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement 206191_at NM_001248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001248.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), mRNA. /FEA=mRNA /GEN=ENTPD3 /PROD=ectonucleoside triphosphate diphosphohydrolase3 /DB_XREF=gi:4557424 /UG=Hs.47042 ectonucleoside triphosphate diphosphohydrolase 3 /FL=gb:AF034840.1 gb:AF039917.1 gb:NM_001248.1 NM_001248 ectonucleoside triphosphate diphosphohydrolase 3 ENTPD3 956 NM_001248 /// NM_001291960 /// NM_001291961 /// XM_005265605 /// XM_005265606 /// XM_005265607 /// XM_005265608 /// XM_006713422 /// XR_245167 /// XR_427297 0008152 // metabolic process // inferred from electronic annotation /// 0009134 // nucleoside diphosphate catabolic process // inferred from electronic annotation /// 0009143 // nucleoside triphosphate catabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 206192_at L20815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20815.1 /DEF=Human S protein mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:414809 /UG=Hs.507 corneodesmosin /FL=gb:AF030130.1 gb:L20815.1 gb:NM_001264.1 L20815 corneodesmosin CDSN 1041 NM_001264 0007155 // cell adhesion // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0030057 // desmosome // inferred from direct assay /// 0030057 // desmosome // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042803 // protein homodimerization activity // inferred from direct assay 206193_s_at NM_001264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001264.1 /DEF=Homo sapiens corneodesmosin (CDSN), mRNA. /FEA=mRNA /GEN=CDSN /PROD=corneodesmosin /DB_XREF=gi:4502758 /UG=Hs.507 corneodesmosin /FL=gb:AF030130.1 gb:L20815.1 gb:NM_001264.1 NM_001264 corneodesmosin CDSN 1041 NM_001264 0007155 // cell adhesion // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0030057 // desmosome // inferred from direct assay /// 0030057 // desmosome // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042803 // protein homodimerization activity // inferred from direct assay 206194_at AW299598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299598 /FEA=EST /DB_XREF=gi:6709275 /DB_XREF=est:xs52b07.x1 /CLONE=IMAGE:2773237 /UG=Hs.50895 homeo box C4 /FL=gb:NM_014620.1 AW299598 homeobox C4 HOXC4 3221 NM_014620 /// NM_153633 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 206195_x_at NM_022557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022557.1 /DEF=Homo sapiens growth hormone 2 (GH2), transcript variant 2, mRNA. /FEA=mRNA /GEN=GH2 /PROD=growth hormone 2, isoform 2 precursor /DB_XREF=gi:13027823 /UG=Hs.65149 growth hormone 2 /FL=gb:NM_022557.1 gb:J03756.1 NM_022557 growth hormone 2 GH2 2689 NM_002059 /// NM_022556 /// NM_022557 /// NM_022558 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 206196_s_at NM_006695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006695.1 /DEF=Homo sapiens RaP2 interacting protein 8 (RPIP8), mRNA. /FEA=mRNA /GEN=RPIP8 /PROD=RaP2 interacting protein 8 /DB_XREF=gi:5730014 /UG=Hs.6755 RaP2 interacting protein 8 /FL=gb:U93871.1 gb:AF055026.1 gb:NM_006695.1 NM_006695 RUN domain containing 3A RUNDC3A 10900 NM_001144825 /// NM_001144826 /// NM_006695 /// XM_005256963 /// XM_005256964 /// XR_243627 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0030250 // guanylate cyclase activator activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 206197_at NM_003551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003551.1 /DEF=Homo sapiens non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) (NME5), mRNA. /FEA=mRNA /GEN=NME5 /PROD=non-metastatic cells 5, protein expressed in(nucleoside-diphosphate kinase) /DB_XREF=gi:4505412 /UG=Hs.72050 non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) /FL=gb:AF067724.1 gb:U90450.1 gb:NM_003551.1 NM_003551 NME/NM23 family member 5 NME5 8382 NM_003551 /// XM_005272098 /// XM_005272099 /// XM_006714716 0003351 // epithelial cilium movement // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0009116 // nucleoside metabolic process // traceable author statement /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048515 // spermatid differentiation // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation 0036126 // sperm flagellum // inferred from electronic annotation 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 206198_s_at L31792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L31792.1 /DEF=Homo sapiens carcinoembryonic antigen (CGM2) mRNA, complete cds. /FEA=mRNA /GEN=CGM2 /PROD=carcinoembryonic antigen /DB_XREF=gi:471076 /UG=Hs.74466 carcinoembryonic antigen-related cell adhesion molecule 7 /FL=gb:AF006622.1 gb:L31792.1 gb:NM_006890.1 L31792 carcinoembryonic antigen-related cell adhesion molecule 7 CEACAM7 1087 NM_001291485 /// NM_006890 /// XM_005258430 /// XM_005278379 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206199_at NM_006890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006890.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7), mRNA. /FEA=mRNA /GEN=CEACAM7 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 7 /DB_XREF=gi:5901929 /UG=Hs.74466 carcinoembryonic antigen-related cell adhesion molecule 7 /FL=gb:AF006622.1 gb:L31792.1 gb:NM_006890.1 NM_006890 carcinoembryonic antigen-related cell adhesion molecule 7 CEACAM7 1087 NM_001291485 /// NM_006890 /// XM_005258430 /// XM_005278379 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206200_s_at NM_001157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001157.1 /DEF=Homo sapiens annexin A11 (ANXA11), mRNA. /FEA=mRNA /GEN=ANXA11 /PROD=annexin XI /DB_XREF=gi:4557316 /UG=Hs.75510 annexin A11 /FL=gb:NM_001157.1 gb:L19605.1 NM_001157 annexin A11 ANXA11 311 NM_001157 /// NM_001278407 /// NM_001278408 /// NM_001278409 /// NM_145868 /// NM_145869 /// XM_005269741 /// XM_005269742 /// XM_006717813 /// XM_006717814 0006909 // phagocytosis // inferred from expression pattern /// 0007049 // cell cycle // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 206201_s_at NM_005924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005924.1 /DEF=Homo sapiens mesenchyme homeo box 2 (growth arrest-specific homeo box) (MEOX2), mRNA. /FEA=mRNA /GEN=MEOX2 /PROD=mesenchyme homeo box 2 /DB_XREF=gi:5174548 /UG=Hs.77858 mesenchyme homeo box 2 (growth arrest-specific homeo box) /FL=gb:NM_005924.1 gb:L36328.1 NM_005924 mesenchyme homeobox 2 MEOX2 4223 NM_005924 0001525 // angiogenesis // inferred from electronic annotation /// 0001757 // somite specification // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0070997 // neuron death // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206202_at NM_005924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005924.1 /DEF=Homo sapiens mesenchyme homeo box 2 (growth arrest-specific homeo box) (MEOX2), mRNA. /FEA=mRNA /GEN=MEOX2 /PROD=mesenchyme homeo box 2 /DB_XREF=gi:5174548 /UG=Hs.77858 mesenchyme homeo box 2 (growth arrest-specific homeo box) /FL=gb:NM_005924.1 gb:L36328.1 NM_005924 mesenchyme homeobox 2 MEOX2 4223 NM_005924 0001525 // angiogenesis // inferred from electronic annotation /// 0001757 // somite specification // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0070997 // neuron death // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206203_at NM_002903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002903.1 /DEF=Homo sapiens recoverin (RCV1), mRNA. /FEA=mRNA /GEN=RCV1 /PROD=recoverin /DB_XREF=gi:4506458 /UG=Hs.80539 recoverin /FL=gb:BC001720.1 gb:AB001838.1 gb:NM_002903.1 NM_002903 recoverin RCVRN 5957 NM_002903 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031284 // positive regulation of guanylate cyclase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation 0030425 // dendrite // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206204_at NM_004490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004490.1 /DEF=Homo sapiens growth factor receptor-bound protein 14 (GRB14), mRNA. /FEA=mRNA /GEN=GRB14 /PROD=growth factor receptor-bound protein 14 /DB_XREF=gi:4758477 /UG=Hs.83070 growth factor receptor-bound protein 14 /FL=gb:L76687.1 gb:NM_004490.1 NM_004490 growth factor receptor-bound protein 14 GRB14 2888 NM_004490 /// XM_005246477 /// XM_006712457 /// XR_427085 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 206205_at NM_022782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022782.1 /DEF=Homo sapiens M-phase phosphoprotein 9 (MPHOSPH9), mRNA. /FEA=mRNA /GEN=MPHOSPH9 /PROD=M-phase phosphoprotein 9 /DB_XREF=gi:13430861 /UG=Hs.86178 M-phase phosphoprotein 9 /FL=gb:NM_022782.1 NM_022782 M-phase phosphoprotein 9 MPHOSPH9 10198 NM_022782 /// NR_103517 /// XM_006719187 /// XM_006719188 /// XM_006719189 /// XM_006719190 /// XM_006719191 /// XM_006719192 /// XR_429068 /// XR_429069 /// XR_429070 0000087 // mitotic M phase // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 206206_at NM_005582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005582.1 /DEF=Homo sapiens lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD (LY64), mRNA. /FEA=mRNA /GEN=LY64 /PROD=lymphocyte antigen 64 (mouse) homolog,radioprotective, 105kD /DB_XREF=gi:5031894 /UG=Hs.87205 lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD /FL=gb:D83597.1 gb:NM_005582.1 NM_005582 CD180 molecule CD180 4064 NM_005582 /// XM_005248504 0002322 // B cell proliferation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from genetic interaction /// 0045087 // innate immune response // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206207_at NM_001828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001828.3 /DEF=Homo sapiens Charot-Leyden crystal protein (CLC), mRNA. /FEA=mRNA /GEN=CLC /PROD=Charot-Leyden crystal protein /DB_XREF=gi:6325464 /UG=Hs.889 Charot-Leyden crystal protein /FL=gb:L01664.1 gb:NM_001828.3 NM_001828 Charcot-Leyden crystal galectin CLC 1178 NM_001828 /// XM_005258501 0002667 // regulation of T cell anergy // inferred from mutant phenotype /// 0002724 // regulation of T cell cytokine production // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0046006 // regulation of activated T cell proliferation // inferred from mutant phenotype /// 0070231 // T cell apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004622 // lysophospholipase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay 206208_at NM_000717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000717.2 /DEF=Homo sapiens carbonic anhydrase IV (CA4), mRNA. /FEA=mRNA /GEN=CA4 /PROD=carbonic anhydrase IV precursor /DB_XREF=gi:9951925 /UG=Hs.89485 carbonic anhydrase IV /FL=gb:M83670.1 gb:NM_000717.2 NM_000717 carbonic anhydrase IV CA4 762 NM_000717 /// XM_005257639 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from mutant phenotype /// 0015701 // bicarbonate transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048513 // organ development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0044459 // plasma membrane part // inferred from direct assay /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206209_s_at NM_000717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000717.2 /DEF=Homo sapiens carbonic anhydrase IV (CA4), mRNA. /FEA=mRNA /GEN=CA4 /PROD=carbonic anhydrase IV precursor /DB_XREF=gi:9951925 /UG=Hs.89485 carbonic anhydrase IV /FL=gb:M83670.1 gb:NM_000717.2 NM_000717 carbonic anhydrase IV CA4 762 NM_000717 /// XM_005257639 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from mutant phenotype /// 0015701 // bicarbonate transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048513 // organ development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0044459 // plasma membrane part // inferred from direct assay /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206210_s_at NM_000078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000078.1 /DEF=Homo sapiens cholesteryl ester transfer protein, plasma (CETP), mRNA. /FEA=mRNA /GEN=CETP /PROD=cholesteryl ester transfer protein, plasmaprecursor /DB_XREF=gi:4557442 /UG=Hs.89538 cholesteryl ester transfer protein, plasma /FL=gb:M30185.1 gb:NM_000078.1 NM_000078 cholesteryl ester transfer protein, plasma CETP 1071 NM_000078 /// NM_001286085 /// XM_006721124 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010874 // regulation of cholesterol efflux // inferred from mutant phenotype /// 0015914 // phospholipid transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred by curator /// 0044281 // small molecule metabolic process // traceable author statement /// 0046470 // phosphatidylcholine metabolic process // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055091 // phospholipid homeostasis // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005319 // lipid transporter activity // inferred from direct assay /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0017129 // triglyceride binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 206211_at NM_000450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000450.1 /DEF=Homo sapiens selectin E (endothelial adhesion molecule 1) (SELE), mRNA. /FEA=mRNA /GEN=SELE /PROD=selectin E precursor /DB_XREF=gi:4506870 /UG=Hs.89546 selectin E (endothelial adhesion molecule 1) /FL=gb:M30640.1 gb:NM_000450.1 gb:M24736.1 NM_000450 selectin E SELE 6401 NM_000450 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0002523 // leukocyte migration involved in inflammatory response // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from mutant phenotype /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007202 // activation of phospholipase C activity // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0030029 // actin filament-based process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from direct assay /// 0043274 // phospholipase binding // inferred from direct assay /// 0070492 // oligosaccharide binding // inferred from direct assay 206212_at NM_001869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001869.1 /DEF=Homo sapiens carboxypeptidase A2 (pancreatic) (CPA2), mRNA. /FEA=mRNA /GEN=CPA2 /PROD=carboxypeptidase A2 (pancreatic) /DB_XREF=gi:4502998 /UG=Hs.89717 carboxypeptidase A2 (pancreatic) /FL=gb:NM_001869.1 gb:U19977.1 NM_001869 carboxypeptidase A2 (pancreatic) CPA2 1358 NM_001869 0006508 // proteolysis // inferred from electronic annotation /// 0007039 // vacuolar protein catabolic process // traceable author statement 0005576 // extracellular region // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from direct assay /// 0004181 // metallocarboxypeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206213_at NM_003394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003394.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 10B (WNT10B), mRNA. /FEA=mRNA /GEN=WNT10B /PROD=wingless-type MMTV integration site family,member 10B /DB_XREF=gi:5803222 /UG=Hs.91985 wingless-type MMTV integration site family, member 10B /FL=gb:U81787.1 gb:NM_003394.1 NM_003394 wingless-type MMTV integration site family, member 10B WNT10B 7480 NM_003394 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0014835 // myoblast differentiation involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051885 // positive regulation of anagen // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0061196 // fungiform papilla development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0071464 // cellular response to hydrostatic pressure // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0048018 // receptor agonist activity // inferred by curator 206214_at NM_005084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005084.1 /DEF=Homo sapiens phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7), mRNA. /FEA=mRNA /GEN=PLA2G7 /PROD=phospholipase A2, group VII (platelet-activatingfactor acetylhydrolase, plasma) /DB_XREF=gi:4826883 /UG=Hs.93304 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) /FL=gb:U24577.1 gb:NM_005084.1 gb:U20157.1 NM_005084 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) PLA2G7 7941 NM_001168357 /// NM_005084 /// XM_005249408 /// XM_005249409 0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0034440 // lipid oxidation // inferred from direct assay /// 0034441 // plasma lipoprotein particle oxidation // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from direct assay 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from direct assay 206215_at NM_002545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002545.2 /DEF=Homo sapiens opioid-binding proteincell adhesion molecule-like (OPCML), mRNA. /FEA=mRNA /GEN=OPCML /PROD=opioid-binding cell adhesion molecule precursor /DB_XREF=gi:13518022 /UG=Hs.99902 opioid-binding proteincell adhesion molecule-like /FL=gb:NM_002545.2 gb:L34774.1 NM_002545 opioid binding protein/cell adhesion molecule-like OPCML 4978 NM_001012393 /// NM_002545 /// XM_005271574 /// XM_005271575 /// XM_005271578 /// XM_005271579 /// XM_006718846 0007155 // cell adhesion // inferred from electronic annotation /// 0008038 // neuron recognition // traceable author statement /// 0038003 // opioid receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004985 // opioid receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206216_at NM_014370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014370.1 /DEF=Homo sapiens serinethreonine kinase 23 (STK23), mRNA. /FEA=mRNA /GEN=STK23 /PROD=serinethreonine kinase 23 /DB_XREF=gi:7657628 /UG=Hs.104865 serinethreonine kinase 23 /FL=gb:U82808.1 gb:AF027406.1 gb:NM_014370.1 NM_014370 SRSF protein kinase 3 SRPK3 26576 NM_001170760 /// NM_001170761 /// NM_014370 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0060537 // muscle tissue development // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206217_at NM_001399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001399.1 /DEF=Homo sapiens ectodermal dysplasia 1, anhidrotic (ED1), mRNA. /FEA=mRNA /GEN=ED1 /PROD=ectodermal dysplasia 1, anhidrotic /DB_XREF=gi:4503448 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF060999.1 gb:AF061189.1 gb:AF040628.1 gb:NM_001399.1 NM_001399 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206218_at NM_002364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002364.1 /DEF=Homo sapiens melanoma antigen, family B, 2 (MAGEB2), mRNA. /FEA=mRNA /GEN=MAGEB2 /PROD=melanoma antigen, family B, 2 /DB_XREF=gi:4505080 /UG=Hs.113824 melanoma antigen, family B, 2 /FL=gb:AF015766.1 gb:NM_002364.1 NM_002364 melanoma antigen family B, 2 MAGEB2 4113 NM_002364 206219_s_at NM_005428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005428.2 /DEF=Homo sapiens vav 1 oncogene (VAV1), mRNA. /FEA=mRNA /GEN=VAV1 /PROD=vav 1 oncogene /DB_XREF=gi:7108366 /UG=Hs.116237 vav 1 oncogene /FL=gb:NM_005428.2 NM_005428 vav 1 guanine nucleotide exchange factor VAV1 7409 NM_001258206 /// NM_001258207 /// NM_005428 /// XM_005259642 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // not recorded /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206220_s_at NM_007368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007368.1 /DEF=Homo sapiens RAS p21 protein activator (GTPase activating protein) 3 (Ins(1,3,4,5)P4-binding protein) (RASA3), mRNA. /FEA=mRNA /GEN=RASA3 /PROD=RAS p21 protein activator 3 /DB_XREF=gi:12545409 /UG=Hs.119274 RAS p21 protein activator (GTPase activating protein) 3 (Ins(1,3,4,5)P4-binding protein) /FL=gb:NM_007368.1 NM_007368 RAS p21 protein activator 3 RASA3 22821 NM_007368 /// XM_005266196 0007165 // signal transduction // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206221_at NM_007368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007368.1 /DEF=Homo sapiens RAS p21 protein activator (GTPase activating protein) 3 (Ins(1,3,4,5)P4-binding protein) (RASA3), mRNA. /FEA=mRNA /GEN=RASA3 /PROD=RAS p21 protein activator 3 /DB_XREF=gi:12545409 /UG=Hs.119274 RAS p21 protein activator (GTPase activating protein) 3 (Ins(1,3,4,5)P4-binding protein) /FL=gb:NM_007368.1 NM_007368 RAS p21 protein activator 3 RASA3 22821 NM_007368 /// XM_005266196 0007165 // signal transduction // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206222_at NM_003841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003841.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C), mRNA. /FEA=mRNA /GEN=TNFRSF10C /PROD=tumor necrosis factor receptor superfamily,member 10c, decoy without an intracellular domain /DB_XREF=gi:10835042 /UG=Hs.119684 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain /FL=gb:NM_003841.1 gb:AF012629.1 gb:AF020502.1 gb:AF016267.1 gb:AF033854.1 gb:AF014794.1 NM_003841 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain TNFRSF10C 8794 NM_003841 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045569 // TRAIL binding // inferred from electronic annotation 206223_at NM_014916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014916.1 /DEF=Homo sapiens KIAA1079 protein (KIAA1079), mRNA. /FEA=mRNA /GEN=KIAA1079 /PROD=KIAA1079 protein /DB_XREF=gi:7662475 /UG=Hs.122708 KIAA1079 protein /FL=gb:AB029002.1 gb:NM_014916.1 NM_014916 lemur tyrosine kinase 2 LMTK2 22853 NM_014916 0001881 // receptor recycling // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0070853 // myosin VI binding // inferred from physical interaction 206224_at NM_001898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001898.1 /DEF=Homo sapiens cystatin SN (CST1), mRNA. /FEA=mRNA /GEN=CST1 /PROD=cystatin SN /DB_XREF=gi:4503102 /UG=Hs.123114 cystatin SN /FL=gb:J03870.1 gb:NM_001898.1 NM_001898 cystatin SN CST1 1469 NM_001898 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206225_at NM_014910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014910.1 /DEF=Homo sapiens KIAA1084 protein (KIAA1084), mRNA. /FEA=mRNA /GEN=KIAA1084 /PROD=KIAA1084 protein /DB_XREF=gi:7662479 /UG=Hs.144028 KIAA1084 protein /FL=gb:AB029007.1 gb:NM_014910.1 NM_014910 zinc finger protein 507 ZNF507 22847 NM_001136156 /// NM_014910 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206226_at NM_000412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000412.2 /DEF=Homo sapiens histidine-rich glycoprotein (HRG), mRNA. /FEA=mRNA /GEN=HRG /PROD=histidine-rich glycoprotein precursor /DB_XREF=gi:13518024 /UG=Hs.1498 histidine-rich glycoprotein /FL=gb:NM_000412.2 gb:M13149.1 NM_000412 histidine-rich glycoprotein HRG 3273 NM_000412 /// XM_005247415 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0002839 // positive regulation of immune response to tumor cell // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010543 // regulation of platelet activation // inferred from sequence or structural similarity /// 0010593 // negative regulation of lamellipodium assembly // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0042730 // fibrinolysis // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from sequence or structural similarity /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050832 // defense response to fungus // inferred from direct assay /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from electronic annotation /// 1900747 // negative regulation of vascular endothelial growth factor signaling pathway // inferred from direct assay /// 2000504 // positive regulation of blood vessel remodeling // inferred from direct assay /// 2001027 // negative regulation of endothelial cell chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0019865 // immunoglobulin binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from direct assay 206227_at NM_003613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003613.1 /DEF=Homo sapiens cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP), mRNA. /FEA=mRNA /GEN=CILP /PROD=cartilage intermediate layer protein /DB_XREF=gi:4502844 /UG=Hs.151407 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase /FL=gb:AF035408.1 gb:NM_003613.1 NM_003613 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase CILP 8483 NM_003613 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0004035 // alkaline phosphatase activity // inferred from direct assay /// 0004551 // nucleotide diphosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 206228_at AW769732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW769732 /FEA=EST /DB_XREF=gi:7701766 /DB_XREF=est:hl68c11.x1 /CLONE=IMAGE:3006356 /UG=Hs.155644 paired box gene 2 /FL=gb:NM_003988.1 AW769732 paired box 2 PAX2 5076 NM_000278 /// NM_003987 /// NM_003988 /// NM_003989 /// NM_003990 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0002072 // optic cup morphogenesis involved in camera-type eye development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0003406 // retinal pigment epithelium development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007501 // mesodermal cell fate specification // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021554 // optic nerve development // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from sequence or structural similarity /// 0021633 // optic nerve structural organization // inferred from sequence or structural similarity /// 0021650 // vestibulocochlear nerve formation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0035566 // regulation of metanephros size // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from sequence or structural similarity /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045918 // negative regulation of cytolysis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048513 // organ development // inferred from electronic annotation /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0061205 // paramesonephric duct development // inferred from electronic annotation /// 0061360 // optic chiasma development // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072172 // mesonephric tubule formation // inferred from electronic annotation /// 0072177 // mesonephric duct development // inferred from electronic annotation /// 0072179 // nephric duct formation // inferred from sequence or structural similarity /// 0072189 // ureter development // inferred from sequence or structural similarity /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072205 // metanephric collecting duct development // inferred from sequence or structural similarity /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 0090102 // cochlea development // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000597 // positive regulation of optic nerve formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from sequence or structural similarity /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from electronic annotation 206229_x_at NM_003988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003988.1 /DEF=Homo sapiens paired box gene 2 (PAX2), transcript variant c, mRNA. /FEA=mRNA /GEN=PAX2 /PROD=paired box protein 2, isoform c /DB_XREF=gi:4557824 /UG=Hs.155644 paired box gene 2 /FL=gb:NM_003988.1 NM_003988 paired box 2 PAX2 5076 NM_000278 /// NM_003987 /// NM_003988 /// NM_003989 /// NM_003990 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0002072 // optic cup morphogenesis involved in camera-type eye development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0003406 // retinal pigment epithelium development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007501 // mesodermal cell fate specification // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021554 // optic nerve development // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from sequence or structural similarity /// 0021633 // optic nerve structural organization // inferred from sequence or structural similarity /// 0021650 // vestibulocochlear nerve formation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0035566 // regulation of metanephros size // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from sequence or structural similarity /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045918 // negative regulation of cytolysis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048513 // organ development // inferred from electronic annotation /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0061205 // paramesonephric duct development // inferred from electronic annotation /// 0061360 // optic chiasma development // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072172 // mesonephric tubule formation // inferred from electronic annotation /// 0072177 // mesonephric duct development // inferred from electronic annotation /// 0072179 // nephric duct formation // inferred from sequence or structural similarity /// 0072189 // ureter development // inferred from sequence or structural similarity /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072205 // metanephric collecting duct development // inferred from sequence or structural similarity /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 0090102 // cochlea development // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000597 // positive regulation of optic nerve formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from sequence or structural similarity /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from electronic annotation 206230_at NM_005568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005568.1 /DEF=Homo sapiens LIM homeobox protein 1 (LHX1), mRNA. /FEA=mRNA /GEN=LHX1 /PROD=LIM homeobox protein 1 /DB_XREF=gi:5031866 /UG=Hs.157449 LIM homeobox protein 1 /FL=gb:NM_005568.1 gb:U14755.1 NM_005568 LIM homeobox 1 LHX1 3975 NM_005568 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from sequence or structural similarity /// 0001705 // ectoderm formation // inferred from sequence or structural similarity /// 0001706 // endoderm formation // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001823 // mesonephros development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from sequence or structural similarity /// 0009653 // anatomical structure morphogenesis // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // traceable author statement /// 0009948 // anterior/posterior axis specification // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021517 // ventral spinal cord development // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0021871 // forebrain regionalization // inferred from sequence or structural similarity /// 0021937 // cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0035502 // metanephric part of ureteric bud development // inferred from electronic annotation /// 0035846 // oviduct epithelium development // inferred from sequence or structural similarity /// 0035847 // uterine epithelium development // inferred from sequence or structural similarity /// 0035849 // nephric duct elongation // inferred from electronic annotation /// 0035852 // horizontal cell localization // inferred from electronic annotation /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from sequence or structural similarity /// 0048793 // pronephros development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060066 // oviduct development // inferred from sequence or structural similarity /// 0060067 // cervix development // inferred from sequence or structural similarity /// 0060068 // vagina development // inferred from sequence or structural similarity /// 0060322 // head development // inferred from sequence or structural similarity /// 0060429 // epithelium development // inferred from sequence or structural similarity /// 0061205 // paramesonephric duct development // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from sequence or structural similarity /// 0072050 // S-shaped body morphogenesis // inferred from sequence or structural similarity /// 0072077 // renal vesicle morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072177 // mesonephric duct development // inferred from electronic annotation /// 0072178 // nephric duct morphogenesis // inferred from sequence or structural similarity /// 0072224 // metanephric glomerulus development // inferred from electronic annotation /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from electronic annotation /// 0072283 // metanephric renal vesicle morphogenesis // inferred from electronic annotation /// 0072284 // metanephric S-shaped body morphogenesis // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0097477 // lateral motor column neuron migration // inferred from sequence or structural similarity /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2000744 // positive regulation of anterior head development // inferred from sequence or structural similarity /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206231_at NM_002248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002248.2 /DEF=Homo sapiens potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 1 (KCNN1), mRNA. /FEA=mRNA /GEN=KCNN1 /PROD=potassium intermediatesmall conductancecalcium-activated channel, subfamily N, member 1 /DB_XREF=gi:6631091 /UG=Hs.158173 potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 1 /FL=gb:U69883.2 gb:NM_002248.2 NM_002248 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 KCNN1 3780 NM_002248 /// XM_005259905 /// XM_005259906 /// XM_005259907 /// XR_244072 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0071805 // potassium ion transmembrane transport // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // traceable author statement /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206232_s_at NM_004775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004775.1 /DEF=Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (B4GALT6), mRNA. /FEA=mRNA /GEN=B4GALT6 /PROD=UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 /DB_XREF=gi:4757829 /UG=Hs.159140 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 /FL=gb:AF038664.1 gb:NM_004775.1 gb:AF097159.1 gb:AB024742.2 NM_004775 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 B4GALT6 9331 NM_004775 /// XM_005258387 /// XM_006722578 /// XM_006722579 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // traceable author statement /// 0008489 // UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206233_at AF097159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF097159.1 /DEF=Homo sapiens UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase mRNA, complete cds. /FEA=mRNA /PROD=UDP-Gal:glucosylceramidebeta-1,4-galactosyltransferase /DB_XREF=gi:5305556 /UG=Hs.159140 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 /FL=gb:AF038664.1 gb:NM_004775.1 gb:AF097159.1 gb:AB024742.2 AF097159 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 B4GALT6 9331 NM_004775 /// XM_005258387 /// XM_006722578 /// XM_006722579 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // traceable author statement /// 0008489 // UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206234_s_at NM_016155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016155.1 /DEF=Homo sapiens matrix metalloproteinase 17 (membrane-inserted) (MMP17), mRNA. /FEA=mRNA /GEN=MMP17 /PROD=matrix metalloproteinase 17 /DB_XREF=gi:7706618 /UG=Hs.159581 matrix metalloproteinase 17 (membrane-inserted) /FL=gb:AB021225.1 gb:NM_016155.1 NM_016155 matrix metallopeptidase 17 (membrane-inserted) MMP17 4326 NM_016155 0006508 // proteolysis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206235_at NM_002312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002312.1 /DEF=Homo sapiens ligase IV, DNA, ATP-dependent (LIG4), mRNA. /FEA=mRNA /GEN=LIG4 /PROD=DNA ligase IV /DB_XREF=gi:4504996 /UG=Hs.166091 ligase IV, DNA, ATP-dependent /FL=gb:NM_002312.1 NM_002312 ligase IV, DNA, ATP-dependent LIG4 3981 NM_001098268 /// NM_002312 /// NM_206937 /// XM_005254056 /// XM_005254057 /// XM_005254058 /// XM_006719950 /// XM_006719951 /// XM_006719952 0000012 // single strand break repair // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from direct assay /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from direct assay /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0010165 // response to X-ray // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from sequence or structural similarity /// 0016032 // viral process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0048146 // positive regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051102 // DNA ligation involved in DNA recombination // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from direct assay /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 0051276 // chromosome organization // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from sequence or structural similarity /// 0032807 // DNA ligase IV complex // inferred from mutant phenotype /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003909 // DNA ligase activity // traceable author statement /// 0003910 // DNA ligase (ATP) activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206236_at NM_005282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005282.1 /DEF=Homo sapiens G protein-coupled receptor 4 (GPR4), mRNA. /FEA=mRNA /GEN=GPR4 /PROD=G protein-coupled receptor 4 /DB_XREF=gi:4885334 /UG=Hs.17170 G protein-coupled receptor 4 /FL=gb:NM_005282.1 NM_005282 G protein-coupled receptor 4 GPR4 2828 NM_005282 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 206237_s_at NM_013957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013957.1 /DEF=Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA. /FEA=mRNA /GEN=NRG1 /PROD=neuregulin 1 isoform HRG-beta2 /DB_XREF=gi:7669513 /UG=Hs.172816 neuregulin 1 /FL=gb:M94167.1 gb:NM_013957.1 NM_013957 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 206238_s_at NM_005748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005748.1 /DEF=Homo sapiens YY1-associated factor 2 (YAF2), mRNA. /FEA=mRNA /GEN=YAF2 /PROD=YY1-associated factor 2 /DB_XREF=gi:5032228 /UG=Hs.180324 YY1-associated factor 2 /FL=gb:NM_005748.1 NM_005748 YY1 associated factor 2 YAF2 10138 NM_001012424 /// NM_001190977 /// NM_001190979 /// NM_001190980 /// NM_005748 /// NR_034000 /// XM_006719183 /// XM_006719184 /// XM_006719185 /// XR_245884 /// XR_245886 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206239_s_at NM_003122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003122.1 /DEF=Homo sapiens serine protease inhibitor, Kazal type 1 (SPINK1), mRNA. /FEA=mRNA /GEN=SPINK1 /PROD=serine protease inhibitor, Kazal type 1 /DB_XREF=gi:4507178 /UG=Hs.181286 serine protease inhibitor, Kazal type 1 /FL=gb:NM_003122.1 NM_003122 serine peptidase inhibitor, Kazal type 1 SPINK1 6690 NM_003122 /// XM_005268501 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from electronic annotation /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0090281 // negative regulation of calcium ion import // inferred from electronic annotation /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206240_s_at NM_003437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003437.1 /DEF=Homo sapiens zinc finger protein 136 (clone pHZ-20) (ZNF136), mRNA. /FEA=mRNA /GEN=ZNF136 /PROD=zinc finger protein 136 (clone pHZ-20) /DB_XREF=gi:4507986 /UG=Hs.182828 zinc finger protein 136 (clone pHZ-20) /FL=gb:NM_003437.1 NM_003437 zinc finger protein 136 ZNF136 7695 NM_003437 /// XM_006722882 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206241_at NM_002269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002269.1 /DEF=Homo sapiens karyopherin alpha 5 (importin alpha 6) (KPNA5), mRNA. /FEA=mRNA /GEN=KPNA5 /PROD=karyopherin alpha 5 (importin alpha 6) /DB_XREF=gi:4504902 /UG=Hs.182971 karyopherin alpha 5 (importin alpha 6) /FL=gb:AF005361.1 gb:NM_002269.1 NM_002269 karyopherin alpha 5 (importin alpha 6) KPNA5 3841 NM_002269 /// XM_005266964 /// XM_006715474 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 206242_at NM_003963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003963.1 /DEF=Homo sapiens transmembrane 4 superfamily member 5 (TM4SF5), mRNA. /FEA=mRNA /GEN=TM4SF5 /PROD=transmembrane 4 superfamily member 5 /DB_XREF=gi:4507538 /UG=Hs.184194 transmembrane 4 superfamily member 5 /FL=gb:AF027204.1 gb:NM_003963.1 NM_003963 transmembrane 4 L six family member 5 TM4SF5 9032 NM_003963 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206243_at NM_003256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003256.1 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 4 (TIMP4), mRNA. /FEA=mRNA /GEN=TIMP4 /PROD=tissue inhibitor of metalloproteinase 4precursor /DB_XREF=gi:4507514 /UG=Hs.190787 tissue inhibitor of metalloproteinase 4 /FL=gb:U76456.1 gb:NM_003256.1 NM_003256 TIMP metallopeptidase inhibitor 4 TIMP4 7079 NM_003256 0007417 // central nervous system development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206244_at NM_000573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000573.1 /DEF=Homo sapiens complement component (3b4b) receptor 1, including Knops blood group system (CR1), mRNA. /FEA=mRNA /GEN=CR1 /PROD=complement component (3b4b) receptor 1,including Knops blood group system /DB_XREF=gi:10834973 /UG=Hs.193716 complement component (3b4b) receptor 1, including Knops blood group system /FL=gb:NM_000573.1 NM_000573 complement component (3b/4b) receptor 1 (Knops blood group) CR1 1378 NM_000573 /// NM_000651 /// XM_005273064 /// XM_006711166 /// XM_006711167 /// XM_006711168 0002376 // immune system process // inferred from electronic annotation /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045957 // negative regulation of complement activation, alternative pathway // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900005 // positive regulation of serine-type endopeptidase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001851 // complement component C3b binding // inferred from direct assay /// 0001855 // complement component C4b binding // inferred from direct assay /// 0001861 // complement component C4b receptor activity // inferred from direct assay /// 0004877 // complement component C3b receptor activity // inferred from direct assay 206245_s_at NM_006469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006469.1 /DEF=Homo sapiens NS1-binding protein (NS1-BP), mRNA. /FEA=mRNA /GEN=NS1-BP /PROD=NS1-binding protein /DB_XREF=gi:5453803 /UG=Hs.197298 NS1-binding protein /FL=gb:NM_006469.1 NM_006469 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 /// NM_016389 /// XM_005244843 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206246_at NM_004567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004567.1 /DEF=Homo sapiens 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 4 (PFKFB4), mRNA. /FEA=mRNA /GEN=PFKFB4 /PROD=6-phosphofructo-2-kinasefructose-2,6-biphosphatase 4 /DB_XREF=gi:4758901 /UG=Hs.198278 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 4 /FL=gb:D49818.1 gb:AF108765.1 gb:NM_004567.1 NM_004567 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 5210 NM_004567 /// XM_005265230 /// XM_005265231 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // non-traceable author statement /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206247_at NM_005931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005931.1 /DEF=Homo sapiens MHC class I polypeptide-related sequence B (MICB), mRNA. /FEA=mRNA /GEN=MICB /PROD=MHC class I polypeptide-related sequence B /DB_XREF=gi:5174564 /UG=Hs.211580 MHC class I polypeptide-related sequence B /FL=gb:NM_005931.1 NM_005931 MHC class I polypeptide-related sequence B MICB 4277 NM_001289160 /// NM_001289161 /// NM_005931 /// XM_006726002 /// XM_006726095 0001913 // T cell mediated cytotoxicity // not recorded /// 0002376 // immune system process // inferred from electronic annotation /// 0002429 // immune response-activating cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0009408 // response to heat // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0032526 // response to retinoic acid // inferred from direct assay /// 0042267 // natural killer cell mediated cytotoxicity // not recorded /// 0046629 // gamma-delta T cell activation // inferred from direct assay /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030881 // beta-2-microglobulin binding // not recorded /// 0046703 // natural killer cell lectin-like receptor binding // inferred from direct assay 206248_at NM_005400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005400.1 /DEF=Homo sapiens protein kinase C, epsilon (PRKCE), mRNA. /FEA=mRNA /GEN=PRKCE /PROD=protein kinase C, epsilon /DB_XREF=gi:4885562 /UG=Hs.211592 protein kinase C, epsilon /FL=gb:NM_005400.1 NM_005400 protein kinase C, epsilon PRKCE 5581 NM_005400 /// XM_005264428 /// XM_005264429 /// XM_005264431 /// XM_006712049 /// XM_006712050 0002281 // macrophage activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010763 // positive regulation of fibroblast migration // inferred from sequence or structural similarity /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035669 // TRAM-dependent toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050996 // positive regulation of lipid catabolic process // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070257 // positive regulation of mucus secretion // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001031 // positive regulation of cellular glucuronidation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0071944 // cell periphery // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from direct assay /// 0004699 // calcium-independent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from mutant phenotype /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030546 // receptor activator activity // inferred from electronic annotation /// 0035276 // ethanol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 206249_at NM_004721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004721.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 13 (MAP3K13), mRNA. /FEA=mRNA /GEN=MAP3K13 /PROD=mitogen-activated protein kinase kinase kinase13 /DB_XREF=gi:4758695 /UG=Hs.21291 mitogen-activated protein kinase kinase kinase 13 /FL=gb:AB001872.1 gb:NM_004721.1 NM_004721 mitogen-activated protein kinase kinase kinase 13 MAP3K13 9175 NM_001242314 /// NM_001242317 /// NM_004721 /// NR_038322 0000186 // activation of MAPKK activity // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206250_x_at AI005066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI005066 /FEA=EST /DB_XREF=gi:3214576 /DB_XREF=est:ou08e11.x1 /CLONE=IMAGE:1625708 /UG=Hs.2131 arginine vasopressin receptor 1A /FL=gb:NM_000706.2 gb:AF030625.1 gb:AF101725.1 gb:L25615.1 AI005066 arginine vasopressin receptor 1A AVPR1A 552 NM_000706 /// XM_005269002 0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from electronic annotation 206251_s_at NM_000706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000706.2 /DEF=Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA. /FEA=mRNA /GEN=AVPR1A /PROD=arginine vasopressin receptor 1A /DB_XREF=gi:13112054 /UG=Hs.2131 arginine vasopressin receptor 1A /FL=gb:NM_000706.2 gb:AF030625.1 gb:AF101725.1 gb:L25615.1 NM_000706 arginine vasopressin receptor 1A AVPR1A 552 NM_000706 /// XM_005269002 0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from electronic annotation 206252_s_at AF030625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF030625.1 /DEF=Homo sapiens SCCL vasopressin subtype 1a receptor mRNA, complete cds. /FEA=mRNA /PROD=SCCL vasopressin subtype 1a receptor /DB_XREF=gi:2623229 /UG=Hs.2131 arginine vasopressin receptor 1A /FL=gb:NM_000706.2 gb:AF030625.1 gb:AF101725.1 gb:L25615.1 AF030625 arginine vasopressin receptor 1A AVPR1A 552 NM_000706 /// XM_005269002 0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from electronic annotation 206253_at NM_001364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001364.1 /DEF=Homo sapiens discs, large (Drosophila) homolog 2 (chapsyn-110) (DLG2), mRNA. /FEA=mRNA /GEN=DLG2 /PROD=discs, large (Drosophila) homolog 2 /DB_XREF=gi:4557526 /UG=Hs.215839 discs, large (Drosophila) homolog 2 (chapsyn-110) /FL=gb:U32376.1 gb:NM_001364.1 NM_001364 discs, large homolog 2 (Drosophila) DLG2 1740 NM_001142699 /// NM_001142700 /// NM_001142702 /// NM_001206769 /// NM_001364 /// XM_005273805 /// XM_005273806 /// XM_005273807 /// XM_005273809 /// XM_005273810 /// XM_005273811 /// XM_006718438 /// XM_006718439 /// XM_006718440 0007268 // synaptic transmission // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206254_at NM_001963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001963.2 /DEF=Homo sapiens epidermal growth factor (beta-urogastrone) (EGF), mRNA. /FEA=mRNA /GEN=EGF /PROD=epidermal growth factor (beta-urogastrone) /DB_XREF=gi:6031163 /UG=Hs.2230 epidermal growth factor (beta-urogastrone) /FL=gb:NM_001963.2 NM_001963 epidermal growth factor EGF 1950 NM_001178130 /// NM_001178131 /// NM_001963 /// XM_005262796 /// XM_005262797 /// XM_005262798 /// XM_005262799 /// XM_005262800 /// XM_005262801 /// XM_005262802 /// XM_006714124 /// XM_006714125 /// XR_427532 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035413 // positive regulation of catenin import into nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 0090370 // negative regulation of cholesterol efflux // inferred from electronic annotation /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000008 // regulation of protein localization to cell surface // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred by curator /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005154 // epidermal growth factor receptor binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // traceable author statement 206255_at NM_001715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001715.1 /DEF=Homo sapiens B lymphoid tyrosine kinase (BLK), mRNA. /FEA=mRNA /GEN=BLK /PROD=B lymphoid tyrosine kinase /DB_XREF=gi:4502412 /UG=Hs.2243 B lymphoid tyrosine kinase /FL=gb:NM_001715.1 NM_001715 BLK proto-oncogene, Src family tyrosine kinase BLK 640 NM_001715 /// XM_005272390 /// XM_006716250 /// XM_006716251 /// XM_006716252 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206256_at NM_001308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001308.1 /DEF=Homo sapiens carboxypeptidase N, polypeptide 1, 50kD (CPN1), mRNA. /FEA=mRNA /GEN=CPN1 /PROD=carboxypeptidase N, polypeptide 1, 50kDprecursor /DB_XREF=gi:4503010 /UG=Hs.2246 carboxypeptidase N, polypeptide 1, 50kD /FL=gb:NM_001308.1 NM_001308 carboxypeptidase N, polypeptide 1 CPN1 1369 NM_001308 0006508 // proteolysis // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206257_at NM_015603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015603.1 /DEF=Homo sapiens DKFZP586M1019 protein (DKFZP586M1019), mRNA. /FEA=mRNA /GEN=DKFZP586M1019 /PROD=DKFZP586M1019 protein /DB_XREF=gi:7661689 /UG=Hs.227782 DKFZP586M1019 protein /FL=gb:BC002787.1 gb:AL050284.1 gb:NM_015603.1 NM_015603 coiled-coil domain containing 9 CCDC9 26093 NM_015603 /// XM_006723133 /// XM_006723134 /// XM_006723135 /// XM_006723136 0044822 // poly(A) RNA binding // inferred from direct assay 206258_at NM_013305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013305.1 /DEF=Homo sapiens alpha2,8-sialyltransferase (HSU91641), mRNA. /FEA=mRNA /GEN=HSU91641 /PROD=alpha2,8-sialyltransferase /DB_XREF=gi:9558746 /UG=Hs.22985 alpha2,8-sialyltransferase /FL=gb:U91641.1 gb:NM_013305.1 NM_013305 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 ST8SIA5 29906 NM_013305 /// XM_005258250 /// XM_006722443 /// XM_006722444 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 206259_at NM_000312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000312.1 /DEF=Homo sapiens protein C (inactivator of coagulation factors Va and VIIIa) (PROC), mRNA. /FEA=mRNA /GEN=PROC /PROD=protein C (inactivator of coagulation factors Vaand VIIIa) /DB_XREF=gi:4506114 /UG=Hs.2351 protein C (inactivator of coagulation factors Va and VIIIa) /FL=gb:NM_000312.1 NM_000312 protein C (inactivator of coagulation factors Va and VIIIa) PROC 5624 NM_000312 /// XM_005263715 /// XM_005263716 /// XM_005263717 /// XM_006712633 0006508 // proteolysis // non-traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206260_at NM_003241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003241.1 /DEF=Homo sapiens transglutaminase 4 (prostate) (TGM4), mRNA. /FEA=mRNA /GEN=TGM4 /PROD=transglutaminase 4 (prostate) /DB_XREF=gi:4507478 /UG=Hs.2387 transglutaminase 4 (prostate) /FL=gb:U31905.1 gb:L34840.1 gb:NM_003241.1 NM_003241 transglutaminase 4 TGM4 7047 NM_003241 /// XM_005265419 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018184 // protein polyamination // non-traceable author statement /// 0042628 // mating plug formation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206261_at NM_005674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005674.1 /DEF=Homo sapiens zinc finger protein 239 (ZNF239), mRNA. /FEA=mRNA /GEN=ZNF239 /PROD=zinc finger protein 239 /DB_XREF=gi:5032244 /UG=Hs.25040 zinc finger protein 239 /FL=gb:NM_005674.1 NM_005674 zinc finger protein 239 ZNF239 8187 NM_001099282 /// NM_001099283 /// NM_001099284 /// NM_005674 /// XM_005271828 /// XM_005271829 /// XM_005271831 /// XM_005271832 /// XM_006718001 /// XM_006718002 /// XM_006718003 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0003723 // RNA binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206262_at NM_000669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000669.2 /DEF=Homo sapiens alcohol dehydrogenase 3 (class I), gamma polypeptide (ADH3), mRNA. /FEA=mRNA /GEN=ADH3 /PROD=class I alcohol dehydrogenase 3 gamma subunit /DB_XREF=gi:11496888 /UG=Hs.2523 alcohol dehydrogenase 3 (class I), gamma polypeptide /FL=gb:NM_000669.2 gb:M12272.1 NM_000669 alcohol dehydrogenase 1C (class I), gamma polypeptide ADH1C 126 NM_000669 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206263_at NM_002022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002022.1 /DEF=Homo sapiens flavin containing monooxygenase 4 (FMO4), mRNA. /FEA=mRNA /GEN=FMO4 /PROD=flavin containing monooxygenase 4 /DB_XREF=gi:4503758 /UG=Hs.2664 flavin containing monooxygenase 4 /FL=gb:BC002780.1 gb:NM_002022.1 NM_002022 flavin containing monooxygenase 4 FMO4 2329 NM_002022 /// XM_005245045 /// XM_005245046 /// XM_005245048 /// XM_006711243 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 206264_at L11702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11702.1 /DEF=Human phospholipase D mRNA, complete cds. /FEA=mRNA /PROD=phospholipase D /DB_XREF=gi:388764 /UG=Hs.272529 glycosylphosphatidylinositol specific phospholipase D1 /FL=gb:L11701.1 gb:L11702.1 gb:NM_001503.1 L11702 glycosylphosphatidylinositol specific phospholipase D1 GPLD1 2822 NM_001503 /// NM_177483 /// XM_005249018 0001503 // ossification // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006507 // GPI anchor release // inferred from direct assay /// 0006507 // GPI anchor release // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010897 // negative regulation of triglyceride catabolic process // inferred from sequence or structural similarity /// 0010907 // positive regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035701 // hematopoietic stem cell migration // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071401 // cellular response to triglyceride // inferred from mutant phenotype /// 0071467 // cellular response to pH // inferred from direct assay /// 0097241 // hematopoietic stem cell migration to bone marrow // traceable author statement /// 1900076 // regulation of cellular response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004621 // glycosylphosphatidylinositol phospholipase D activity // inferred from direct assay /// 0004621 // glycosylphosphatidylinositol phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity 206265_s_at NM_001503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001503.1 /DEF=Homo sapiens glycosylphosphatidylinositol specific phospholipase D1 (GPLD1), mRNA. /FEA=mRNA /GEN=GPLD1 /PROD=glycosylphosphatidylinositol specificphospholipase D1 /DB_XREF=gi:4504088 /UG=Hs.272529 glycosylphosphatidylinositol specific phospholipase D1 /FL=gb:L11701.1 gb:L11702.1 gb:NM_001503.1 NM_001503 glycosylphosphatidylinositol specific phospholipase D1 GPLD1 2822 NM_001503 /// NM_177483 /// XM_005249018 0001503 // ossification // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006507 // GPI anchor release // inferred from direct assay /// 0006507 // GPI anchor release // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010897 // negative regulation of triglyceride catabolic process // inferred from sequence or structural similarity /// 0010907 // positive regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035701 // hematopoietic stem cell migration // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071401 // cellular response to triglyceride // inferred from mutant phenotype /// 0071467 // cellular response to pH // inferred from direct assay /// 0097241 // hematopoietic stem cell migration to bone marrow // traceable author statement /// 1900076 // regulation of cellular response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004621 // glycosylphosphatidylinositol phospholipase D activity // inferred from direct assay /// 0004621 // glycosylphosphatidylinositol phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity 206266_at NM_001503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001503.1 /DEF=Homo sapiens glycosylphosphatidylinositol specific phospholipase D1 (GPLD1), mRNA. /FEA=mRNA /GEN=GPLD1 /PROD=glycosylphosphatidylinositol specificphospholipase D1 /DB_XREF=gi:4504088 /UG=Hs.272529 glycosylphosphatidylinositol specific phospholipase D1 /FL=gb:L11701.1 gb:L11702.1 gb:NM_001503.1 NM_001503 glycosylphosphatidylinositol specific phospholipase D1 GPLD1 2822 NM_001503 /// NM_177483 /// XM_005249018 0001503 // ossification // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006507 // GPI anchor release // inferred from direct assay /// 0006507 // GPI anchor release // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010897 // negative regulation of triglyceride catabolic process // inferred from sequence or structural similarity /// 0010907 // positive regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035701 // hematopoietic stem cell migration // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071401 // cellular response to triglyceride // inferred from mutant phenotype /// 0071467 // cellular response to pH // inferred from direct assay /// 0097241 // hematopoietic stem cell migration to bone marrow // traceable author statement /// 1900076 // regulation of cellular response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004621 // glycosylphosphatidylinositol phospholipase D activity // inferred from direct assay /// 0004621 // glycosylphosphatidylinositol phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity 206267_s_at NM_002378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002378.1 /DEF=Homo sapiens megakaryocyte-associated tyrosine kinase (MATK), mRNA. /FEA=mRNA /GEN=MATK /PROD=megakaryocyte-associated tyrosine kinase /DB_XREF=gi:4505108 /UG=Hs.274 megakaryocyte-associated tyrosine kinase /FL=gb:BC000114.1 gb:BC003109.1 gb:NM_002378.1 gb:L18974.1 NM_002378 megakaryocyte-associated tyrosine kinase MATK 4145 NM_002378 /// NM_139354 /// NM_139355 0006468 // protein phosphorylation // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206268_at NM_020997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020997.1 /DEF=Homo sapiens left-right determination, factor B (LEFTB), mRNA. /FEA=mRNA /GEN=LEFTB /PROD=left-right determination, factor B /DB_XREF=gi:10337602 /UG=Hs.278239 left-right determination, factor B /FL=gb:NM_020997.1 gb:AF081512.1 NM_020997 left-right determination factor 1 LEFTY1 10637 NM_020997 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0016049 // cell growth // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206269_at AB026493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026493.1 /DEF=Homo sapiens mRNA for GCM motif protein, complete cds. /FEA=mRNA /PROD=GCM motif protein /DB_XREF=gi:4730818 /UG=Hs.28346 glial cells missing (Drosophila) homolog a /FL=gb:D88613.1 gb:NM_003643.1 gb:AB026493.1 gb:AB041714.1 AB026493 glial cells missing homolog 1 (Drosophila) GCM1 8521 NM_003643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060143 // positive regulation of syncytium formation by plasma membrane fusion // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206270_at NM_002739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002739.1 /DEF=Homo sapiens protein kinase C, gamma (PRKCG), mRNA. /FEA=mRNA /GEN=PRKCG /PROD=protein kinase C, gamma /DB_XREF=gi:13384593 /UG=Hs.2890 protein kinase C, gamma /FL=gb:AF345987.1 gb:NM_002739.1 NM_002739 protein kinase C, gamma PRKCG 5582 NM_002739 0006468 // protein phosphorylation // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007635 // chemosensory behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032425 // positive regulation of mismatch repair // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0060384 // innervation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // traceable author statement /// 0004698 // calcium-dependent protein kinase C activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206271_at NM_003265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003265.1 /DEF=Homo sapiens toll-like receptor 3 (TLR3), mRNA. /FEA=mRNA /GEN=TLR3 /PROD=toll-like receptor3 /DB_XREF=gi:4507530 /UG=Hs.29499 toll-like receptor 3 /FL=gb:U88879.1 gb:NM_003265.1 NM_003265 toll-like receptor 3 TLR3 7098 NM_003265 /// XM_006714294 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006972 // hyperosmotic response // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009597 // detection of virus // non-traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034123 // positive regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034346 // positive regulation of type III interferon production // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042742 // defense response to bacterium // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from direct assay /// 0043331 // response to dsRNA // inferred from electronic annotation /// 0045078 // positive regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045356 // positive regulation of interferon-alpha biosynthetic process // inferred from direct assay /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from direct assay /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from mutant phenotype /// 0045671 // negative regulation of osteoclast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051607 // defense response to virus // traceable author statement /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071359 // cellular response to dsRNA // inferred from electronic annotation /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036020 // endolysosome membrane // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // non-traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206272_at NM_006542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006542.1 /DEF=Homo sapiens S-phase response (cyclin-related) (SPHAR), mRNA. /FEA=mRNA /GEN=SPHAR /PROD=S-phase response (cyclin-related) /DB_XREF=gi:5730062 /UG=Hs.296169 S-phase response (cyclin-related) /FL=gb:NM_006542.1 NM_006542 RAB4A, member RAS oncogene family /// S-phase response (cyclin related) RAB4A /// SPHAR 5867 /// 10638 NM_001271998 /// NM_004578 /// NM_006542 /// NR_073545 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 206273_at NM_006553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006553.1 /DEF=Homo sapiens erythroid differentiation and denucleation factor 1 (HFL-EDDG1), mRNA. /FEA=mRNA /GEN=HFL-EDDG1 /PROD=erythroid differentiation and denucleationfactor 1 /DB_XREF=gi:5921494 /UG=Hs.296434 erythroid differentiation and denucleation factor 1 /FL=gb:AF048849.1 gb:NM_006553.1 NM_006553 slowmo homolog 1 (Drosophila) SLMO1 10650 NM_001142405 /// NM_001142406 /// NM_006553 0015914 // phospholipid transport // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // not recorded 1990050 // phosphatidic acid transporter activity // not recorded 206274_s_at NM_014675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014675.1 /DEF=Homo sapiens KIAA0445 gene product (KIAA0445), mRNA. /FEA=mRNA /GEN=KIAA0445 /PROD=KIAA0445 gene product /DB_XREF=gi:7662131 /UG=Hs.301065 KIAA0445 gene product /FL=gb:AB007914.1 gb:NM_014675.1 NM_014675 ciliary rootlet coiled-coil, rootletin CROCC 9696 NM_014675 /// XM_006711056 /// XM_006711057 /// XM_006711058 /// XM_006711059 /// XM_006711060 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from sequence or structural similarity 206275_s_at NM_014632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014632.1 /DEF=Homo sapiens KIAA0750 gene product (KIAA0750), mRNA. /FEA=mRNA /GEN=KIAA0750 /PROD=KIAA0750 gene product /DB_XREF=gi:7662283 /UG=Hs.314434 KIAA0750 gene product /FL=gb:AB018293.1 gb:NM_014632.1 NM_014632 microtubule associated monooxygenase, calponin and LIM domain containing 2 MICAL2 9645 NM_001282663 /// NM_001282664 /// NM_001282665 /// NM_001282666 /// NM_001282667 /// NM_001282668 /// NM_014632 /// XM_005253249 /// XM_005253251 /// XM_006718391 /// XM_006718392 /// XM_006718393 0001947 // heart looping // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from mutant phenotype /// 0019417 // sulfur oxidation // inferred from direct assay /// 0019417 // sulfur oxidation // inferred from sequence or structural similarity /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from sequence or structural similarity /// 0043914 // NADPH:sulfur oxidoreductase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity 206276_at NM_003695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003695.1 /DEF=Homo sapiens lymphocyte antigen 6 complex, locus D (E48), mRNA. /FEA=mRNA /GEN=E48 /PROD=lymphocyte antigen 6 complex, locus D /DB_XREF=gi:11321574 /UG=Hs.3185 lymphocyte antigen 6 complex, locus D /FL=gb:NM_003695.1 NM_003695 lymphocyte antigen 6 complex, locus D LY6D 8581 NM_003695 0007155 // cell adhesion // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 206277_at NM_002564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002564.1 /DEF=Homo sapiens purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), mRNA. /FEA=mRNA /GEN=P2RY2 /PROD=purinergic receptor P2Y, G-protein coupled, 2 /DB_XREF=gi:4505558 /UG=Hs.339 purinergic receptor P2Y, G-protein coupled, 2 /FL=gb:NM_002564.1 gb:U07225.1 NM_002564 purinergic receptor P2Y, G-protein coupled, 2 P2RY2 5029 NM_002564 /// NM_176071 /// NM_176072 /// XM_005274019 /// XM_005274020 /// XM_005274021 0006873 // cellular ion homeostasis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0070257 // positive regulation of mucus secretion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation 206278_at D10202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D10202.1 /DEF=Homo sapiens mRNA for platelet-activating factor receptor, complete cds. /FEA=mRNA /PROD=platelet-activating factor receptor /DB_XREF=gi:219975 /UG=Hs.46 platelet-activating factor receptor /FL=gb:L07334.1 gb:D10202.1 gb:NM_000952.1 gb:M76674.1 D10202 platelet-activating factor receptor PTAFR 5724 NM_000952 /// NM_001164721 /// NM_001164722 /// NM_001164723 0001816 // cytokine production // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032959 // inositol trisphosphate biosynthetic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0001875 // lipopolysaccharide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004992 // platelet activating factor receptor activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay 206279_at NM_002760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002760.1 /DEF=Homo sapiens protein kinase, Y-linked (PRKY), mRNA. /FEA=mRNA /GEN=PRKY /PROD=protein kinase, Y-linked /DB_XREF=gi:10835064 /UG=Hs.56336 protein kinase, Y-linked /FL=gb:NM_002760.1 NM_002760 protein kinase, Y-linked, pseudogene PRKY 5616 NM_002760 /// NR_028062 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206280_at NM_004934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004934.1 /DEF=Homo sapiens cadherin 18, type 2 (CDH18), mRNA. /FEA=mRNA /GEN=CDH18 /PROD=cadherin 18, type 2 /DB_XREF=gi:4826670 /UG=Hs.57691 cadherin 18, type 2 /FL=gb:U59325.1 gb:NM_004934.1 NM_004934 cadherin 18, type 2 CDH18 1016 NM_001167667 /// NM_001291956 /// NM_001291957 /// NM_004934 /// XM_005248228 /// XM_006714435 /// XM_006714436 /// XM_006714437 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206281_at NM_001117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001117.2 /DEF=Homo sapiens adenylate cyclase activating polypeptide 1 (pituitary) (ADCYAP1), mRNA. /FEA=mRNA /GEN=ADCYAP1 /PROD=adenylate cyclase activating polypeptideprecursor /DB_XREF=gi:10947062 /UG=Hs.68137 adenylate cyclase activating polypeptide 1 (pituitary) /FL=gb:NM_001117.2 NM_001117 adenylate cyclase activating polypeptide 1 (pituitary) ADCYAP1 116 NM_001099733 /// NM_001117 /// XM_005258081 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0002865 // negative regulation of acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002878 // negative regulation of acute inflammatory response to non-antigenic stimulus // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0034259 // negative regulation of Rho GTPase activity // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070445 // regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0090274 // positive regulation of somatostatin secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // inferred from direct assay /// 0016521 // pituitary adenylate cyclase activating polypeptide activity // inferred from direct assay /// 0031858 // pituitary adenylate cyclase-activating polypeptide receptor binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from direct assay /// 0051428 // peptide hormone receptor binding // inferred from physical interaction 206282_at NM_002500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002500.1 /DEF=Homo sapiens neurogenic differentiation 1 (NEUROD1), mRNA. /FEA=mRNA /GEN=NEUROD1 /PROD=neurogenic differentiation 1 /DB_XREF=gi:4505376 /UG=Hs.72981 neurogenic differentiation 1 /FL=gb:D82347.1 gb:NM_002500.1 NM_002500 neuronal differentiation 1 NEUROD1 4760 NM_002500 0003326 // pancreatic A cell fate commitment // inferred from electronic annotation /// 0003329 // pancreatic PP cell fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009749 // response to glucose // inferred from mutant phenotype /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0022008 // neurogenesis // traceable author statement /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // traceable author statement /// 0035881 // amacrine cell differentiation // inferred from sequence or structural similarity /// 0035883 // enteroendocrine cell differentiation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060730 // regulation of intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0071156 // regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from sequence or structural similarity /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 206283_s_at NM_003189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003189.1 /DEF=Homo sapiens T-cell acute lymphocytic leukemia 1 (TAL1), mRNA. /FEA=mRNA /GEN=TAL1 /PROD=T-cell acute lymphocytic leukemia 1 /DB_XREF=gi:4507362 /UG=Hs.73828 T-cell acute lymphocytic leukemia 1 /FL=gb:M29038.1 gb:NM_003189.1 gb:M61108.1 NM_003189 T-cell acute lymphocytic leukemia 1 TAL1 6886 NM_001287347 /// NM_001290403 /// NM_001290404 /// NM_001290405 /// NM_001290406 /// NM_003189 /// XM_005271158 /// XM_005271159 /// XM_005271160 /// XM_006710862 /// XM_006710863 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030219 // megakaryocyte differentiation // inferred from expression pattern /// 0030220 // platelet formation // inferred from electronic annotation /// 0030221 // basophil differentiation // inferred from expression pattern /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045799 // positive regulation of chromatin assembly or disassembly // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048699 // generation of neurons // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060217 // hemangioblast cell differentiation // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060375 // regulation of mast cell differentiation // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0033193 // Lsd1/2 complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 206284_x_at NM_001834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001834.1 /DEF=Homo sapiens clathrin, light polypeptide (Lcb) (CLTB), transcript variant nonbrain, mRNA. /FEA=mRNA /GEN=CLTB /PROD=clathrin, light polypeptide B (Lcb) isoform a /DB_XREF=gi:4502900 /UG=Hs.73919 clathrin, light polypeptide (Lcb) /FL=gb:M20470.1 gb:NM_001834.1 NM_001834 clathrin, light chain B CLTB 1212 NM_001834 /// NM_007097 /// NR_045724 /// XM_006714818 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 206285_at NM_000272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000272.1 /DEF=Homo sapiens nephronophthisis 1 (juvenile) (NPHP1), mRNA. /FEA=mRNA /GEN=NPHP1 /PROD=nephrocystin /DB_XREF=gi:4557804 /UG=Hs.75474 nephronophthisis 1 (juvenile) /FL=gb:NM_000272.1 NM_000272 nephronophthisis 1 (juvenile) NPHP1 4867 NM_000272 /// NM_001128178 /// NM_001128179 /// NM_207181 /// XM_005263675 /// XM_005263676 /// XM_005263677 /// XM_005263678 /// XM_005263679 /// XM_006712551 /// XM_006712552 0007165 // signal transduction // non-traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007632 // visual behavior // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030030 // cell projection organization // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035845 // photoreceptor cell outer segment organization // inferred from electronic annotation /// 0048515 // spermatid differentiation // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206286_s_at NM_003212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003212.1 /DEF=Homo sapiens teratocarcinoma-derived growth factor 1 (TDGF1), mRNA. /FEA=mRNA /GEN=TDGF1 /PROD=teratocarcinoma-derived growth factor 1 /DB_XREF=gi:4507424 /UG=Hs.75561 teratocarcinoma-derived growth factor 1 /FL=gb:NM_003212.1 NM_003212 teratocarcinoma-derived growth factor 1 /// teratocarcinoma-derived growth factor 1 pseudogene 3 TDGF1 /// TDGF1P3 6997 /// 6998 NM_001174136 /// NM_003212 /// NR_002718 0000187 // activation of MAPK activity // inferred from direct assay /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // traceable author statement /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008595 // anterior/posterior axis specification, embryo // inferred from sequence or structural similarity /// 0009790 // embryo development // traceable author statement /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030879 // mammary gland development // traceable author statement /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071354 // cellular response to interleukin-6 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009279 // cell outer membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement 206287_s_at NM_002218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002218.1 /DEF=Homo sapiens inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) (ITIH4), mRNA. /FEA=mRNA /GEN=ITIH4 /PROD=inter-alpha (globulin) inhibitor H4 (plasmaKallikrein-sensitive glycoprotein) /DB_XREF=gi:4504784 /UG=Hs.76415 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) /FL=gb:NM_002218.1 gb:D38595.1 NM_002218 inter-alpha-trypsin inhibitor heavy chain family, member 4 ITIH4 3700 NM_001166449 /// NM_002218 0006953 // acute-phase response // inferred from expression pattern /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206288_at NM_005023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005023.1 /DEF=Homo sapiens protein geranylgeranyltransferase type I, beta subunit (PGGT1B), mRNA. /FEA=mRNA /GEN=PGGT1B /PROD=protein geranylgeranyltransferase type I, betasubunit /DB_XREF=gi:4826899 /UG=Hs.766 protein geranylgeranyltransferase type I, beta subunit /FL=gb:L25441.1 gb:NM_005023.1 NM_005023 protein geranylgeranyltransferase type I, beta subunit PGGT1B 5229 NM_005023 /// XM_005272020 /// XM_005272022 /// XM_005272023 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0051771 // negative regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation 0005953 // CAAX-protein geranylgeranyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004661 // protein geranylgeranyltransferase activity // inferred from direct assay /// 0004662 // CAAX-protein geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206289_at NM_002141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002141.1 /DEF=Homo sapiens homeo box A4 (HOXA4), mRNA. /FEA=mRNA /GEN=HOXA4 /PROD=homeo box A4 /DB_XREF=gi:4504458 /UG=Hs.77637 homeo box A4 /FL=gb:M74297.1 gb:NM_002141.1 NM_002141 homeobox A4 HOXA4 3201 NM_002141 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206290_s_at NM_002924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002924.1 /DEF=Homo sapiens regulator of G-protein signalling 7 (RGS7), mRNA. /FEA=mRNA /GEN=RGS7 /PROD=regulator of G-protein signalling 7 /DB_XREF=gi:11140808 /UG=Hs.79348 regulator of G-protein signalling 7 /FL=gb:NM_002924.1 gb:AF090116.1 NM_002924 regulator of G-protein signaling 7 RGS7 6000 NM_001282773 /// NM_001282775 /// NM_001282778 /// NM_002924 /// XM_005273218 /// XM_005273221 /// XM_006711800 /// XM_006711801 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // non-traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0044292 // dendrite terminus // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0031681 // G-protein beta-subunit binding // inferred from physical interaction 206291_at NM_006183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006183.2 /DEF=Homo sapiens neurotensin (NTS), mRNA. /FEA=mRNA /GEN=NTS /PROD=neurotensin precursor /DB_XREF=gi:6006028 /UG=Hs.80962 neurotensin /FL=gb:U91618.1 gb:NM_006183.2 NM_006183 neurotensin NTS 4922 NM_006183 0007165 // signal transduction // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206292_s_at NM_003167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003167.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1 (SULT2A1), mRNA. /FEA=mRNA /GEN=SULT2A1 /PROD=sulfotransferase family, cytosolic, 2A,dehydroepiandrosterone (DHEA) -preferring, member 1 /DB_XREF=gi:4507306 /UG=Hs.81884 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1 /FL=gb:L20000.1 gb:NM_003167.1 gb:U08024.1 gb:U08025.1 NM_003167 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 SULT2A1 6822 NM_003167 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007586 // digestion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030573 // bile acid catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047704 // bile-salt sulfotransferase activity // inferred from electronic annotation 206293_at U08024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U08024.1 /DEF=Human clone A dehydroepiandrosterone sulfotransferase (STD) mRNA, complete cds. /FEA=mRNA /GEN=STD /PROD=dehydroepiandrosterone sulfotransferase /DB_XREF=gi:468250 /UG=Hs.81884 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1 /FL=gb:L20000.1 gb:NM_003167.1 gb:U08024.1 gb:U08025.1 U08024 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 SULT2A1 6822 NM_003167 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007586 // digestion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030573 // bile acid catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047704 // bile-salt sulfotransferase activity // inferred from electronic annotation 206294_at NM_000198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000198.1 /DEF=Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), mRNA. /FEA=mRNA /GEN=HSD3B2 /PROD=hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2 /DB_XREF=gi:4504508 /UG=Hs.825 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 /FL=gb:M67466.1 gb:NM_000198.1 NM_000198 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 HSD3B2 3284 NM_000198 /// NM_001166120 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006702 // androgen biosynthetic process // traceable author statement /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030868 // smooth endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from direct assay /// 0004769 // steroid delta-isomerase activity // inferred from direct assay /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 206295_at NM_001562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001562.1 /DEF=Homo sapiens interleukin 18 (interferon-gamma-inducing factor) (IL18), mRNA. /FEA=mRNA /GEN=IL18 /PROD=interleukin 18 /DB_XREF=gi:4504652 /UG=Hs.83077 interleukin 18 (interferon-gamma-inducing factor) /FL=gb:D49950.1 gb:AF077611.1 gb:NM_001562.1 NM_001562 interleukin 18 IL18 3606 NM_001243211 /// NM_001562 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030101 // natural killer cell activation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030431 // sleep // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042033 // chemokine biosynthetic process // traceable author statement /// 0042088 // T-helper 1 type immune response // inferred from direct assay /// 0042092 // type 2 immune response // traceable author statement /// 0042094 // interleukin-2 biosynthetic process // traceable author statement /// 0042095 // interferon-gamma biosynthetic process // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042231 // interleukin-13 biosynthetic process // traceable author statement /// 0042253 // granulocyte macrophage colony-stimulating factor biosynthetic process // traceable author statement /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 2000256 // positive regulation of male germ cell proliferation // inferred from electronic annotation /// 2000504 // positive regulation of blood vessel remodeling // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // traceable author statement 206296_x_at NM_007181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007181.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1), mRNA. /FEA=mRNA /GEN=MAP4K1 /PROD=mitogen-activated protein kinase kinase kinasekinase 1 /DB_XREF=gi:6005809 /UG=Hs.86575 mitogen-activated protein kinase kinase kinase kinase 1 /FL=gb:U66464.1 gb:NM_007181.1 NM_007181 mitogen-activated protein kinase kinase kinase kinase 1 MAP4K1 11184 NM_001042600 /// NM_007181 /// XM_006722993 0000185 // activation of MAPKKK activity // inferred by curator /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206297_at NM_007272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007272.1 /DEF=Homo sapiens chymotrypsin C (caldecrin) (CTRC), mRNA. /FEA=mRNA /GEN=CTRC /PROD=chymotrypsin C (caldecrin) /DB_XREF=gi:11321627 /UG=Hs.8709 chymotrypsin C (caldecrin) /FL=gb:NM_007272.1 gb:S82198.1 NM_007272 chymotrypsin C (caldecrin) CTRC 11330 NM_007272 0006508 // proteolysis // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 206298_at NM_021226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021226.1 /DEF=Homo sapiens hypothetical protein from clones 23549 and 23762 (LOC58504), mRNA. /FEA=mRNA /GEN=LOC58504 /PROD=hypothetical protein from clones 23549 and23762 /DB_XREF=gi:10864038 /UG=Hs.87241 hypothetical protein from clones 23549 and 23762 /FL=gb:NM_021226.1 gb:U90908.1 NM_021226 Rho GTPase activating protein 22 ARHGAP22 58504 NM_001256024 /// NM_001256025 /// NM_001256026 /// NM_001256027 /// NM_021226 /// NR_045675 /// XM_005270014 /// XM_006717934 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 206299_at NM_015686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015686.1 /DEF=Homo sapiens TED protein (TED), mRNA. /FEA=mRNA /GEN=TED /PROD=TED protein /DB_XREF=gi:7662670 /UG=Hs.87619 TED protein /FL=gb:AF087142.1 gb:NM_015686.1 NM_015686 family with sequence similarity 155, member B FAM155B 27112 NM_015686 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206300_s_at NM_002820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002820.1 /DEF=Homo sapiens parathyroid hormone-like hormone (PTHLH), mRNA. /FEA=mRNA /GEN=PTHLH /PROD=parathyroid hormone-like hormone /DB_XREF=gi:4506268 /UG=Hs.89626 parathyroid hormone-like hormone /FL=gb:J03802.1 gb:NM_002820.1 NM_002820 parathyroid hormone-like hormone PTHLH 5744 NM_002820 /// NM_198964 /// NM_198965 /// NM_198966 /// XM_005253434 /// XM_006719115 0001501 // skeletal system development // inferred from direct assay /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0016485 // protein processing // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046058 // cAMP metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060649 // mammary gland bud elongation // inferred from electronic annotation /// 0060659 // nipple sheath formation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from direct assay 206301_at NM_003215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003215.1 /DEF=Homo sapiens tec protein tyrosine kinase (TEC), mRNA. /FEA=mRNA /GEN=TEC /PROD=tec protein tyrosine kinase /DB_XREF=gi:4507428 /UG=Hs.89656 tec protein tyrosine kinase /FL=gb:NM_003215.1 gb:D29767.1 NM_003215 tec protein tyrosine kinase TEC 7006 NM_003215 /// XM_005248123 /// XM_006714027 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0010543 // regulation of platelet activation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206302_s_at NM_019094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019094.1 /DEF=Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 4 (NUDT4), mRNA. /FEA=mRNA /GEN=NUDT4 /PROD=nudix (nucleoside diphosphate linked moietyX)-type motif 4 /DB_XREF=gi:10800135 /UG=Hs.92381 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /FL=gb:NM_019094.1 gb:AF191649.1 gb:AF191650.1 gb:AF191653.1 NM_019094 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 2 NUDT4 /// NUDT4P1 /// NUDT4P2 11163 /// 170688 /// 440672 NM_019094 /// NM_199040 /// NR_002212 /// NR_104005 /// XM_005268595 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0019935 // cyclic-nucleotide-mediated signaling // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046831 // regulation of RNA export from nucleus // traceable author statement /// 0046907 // intracellular transport // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // traceable author statement /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 206303_s_at AF191653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF191653.1 /DEF=Homo sapiens diphosphoinositol polyphosphate phosphohydrolase type 2 beta (NUDT4) mRNA, complete cds. /FEA=mRNA /GEN=NUDT4 /PROD=diphosphoinositol polyphosphate phosphohydrolasetype 2 beta /DB_XREF=gi:7739471 /UG=Hs.92381 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /FL=gb:NM_019094.1 gb:AF191649.1 gb:AF191650.1 gb:AF191653.1 AF191653 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 2 NUDT4 /// NUDT4P1 /// NUDT4P2 11163 /// 170688 /// 440672 NM_019094 /// NM_199040 /// NR_002212 /// NR_104005 /// XM_005268595 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0019935 // cyclic-nucleotide-mediated signaling // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046831 // regulation of RNA export from nucleus // traceable author statement /// 0046907 // intracellular transport // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // traceable author statement /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 206304_at NM_004997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004997.1 /DEF=Homo sapiens myosin-binding protein H (MYBPH), mRNA. /FEA=mRNA /GEN=MYBPH /PROD=myosin-binding protein H /DB_XREF=gi:4826841 /UG=Hs.927 myosin-binding protein H /FL=gb:L05606.1 gb:NM_004997.1 NM_004997 myosin binding protein H MYBPH 4608 NM_004997 /// XM_005245196 /// XM_005245197 0006942 // regulation of striated muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation 0032982 // myosin filament // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 206305_s_at NM_000562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000562.1 /DEF=Homo sapiens complement component 8, alpha polypeptide (C8A), mRNA. /FEA=mRNA /GEN=C8A /PROD=complement component 8, alpha polypeptideprecursor /DB_XREF=gi:4557388 /UG=Hs.93210 complement component 8, alpha polypeptide /FL=gb:M16974.1 gb:NM_000562.1 NM_000562 complement component 8, alpha polypeptide C8A 731 NM_000562 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006956 // complement activation // inferred from direct assay /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from direct assay /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 206306_at NM_001036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001036.1 /DEF=Homo sapiens ryanodine receptor 3 (RYR3), mRNA. /FEA=mRNA /GEN=RYR3 /PROD=ryanodine receptor 3 /DB_XREF=gi:4506758 /UG=Hs.9349 ryanodine receptor 3 /FL=gb:AB001025.1 gb:AJ001515.1 gb:NM_001036.1 NM_001036 ryanodine receptor 3 RYR3 6263 NM_001036 /// NM_001243996 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071286 // cellular response to magnesium ion // inferred from sequence or structural similarity /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071318 // cellular response to ATP // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030314 // junctional membrane complex // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0015278 // calcium-release channel activity // inferred from mutant phenotype /// 0048763 // calcium-induced calcium release activity // inferred from electronic annotation 206307_s_at NM_004472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004472.1 /DEF=Homo sapiens forkhead box D1 (FOXD1), mRNA. /FEA=mRNA /GEN=FOXD1 /PROD=forkhead box D1 /DB_XREF=gi:4758391 /UG=Hs.96028 forkhead box D1 /FL=gb:U59832.1 gb:NM_004472.1 NM_004472 forkhead box D1 FOXD1 2297 NM_004472 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060678 // dichotomous subdivision of terminal units involved in ureteric bud branching // inferred from sequence or structural similarity /// 0072076 // nephrogenic mesenchyme development // inferred from electronic annotation /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 0072213 // metanephric capsule development // inferred from sequence or structural similarity /// 0072267 // metanephric capsule specification // inferred from sequence or structural similarity /// 0072268 // pattern specification involved in metanephros development // inferred from electronic annotation /// 0090184 // positive regulation of kidney development // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008301 // DNA binding, bending // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206308_at AJ223333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AJ223333.1 /DEF=Homo sapiens mRNA for putative DNA methyltransferase, complete CDS. /FEA=mRNA /PROD=DNA methyltransferase /DB_XREF=gi:2894543 /UG=Hs.97681 DNA (cytosine-5-)-methyltransferase 2 /FL=gb:AF012128.1 gb:AJ223333.1 gb:AF045888.1 gb:NM_004412.1 AJ223333 tRNA aspartic acid methyltransferase 1 TRDMT1 1787 NM_004412 /// NM_176081 /// NM_176083 /// NM_176084 /// NM_176085 /// NM_176086 /// XM_005252372 /// XM_005252373 /// XM_005252374 /// XM_005252375 /// XM_005252376 /// XM_005252378 /// XM_006717388 0001975 // response to amphetamine // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0090116 // C-5 methylation of cytosine // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008175 // tRNA methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 206309_at NM_007015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007015.1 /DEF=Homo sapiens chondromodulin I precursor (CHM-I), mRNA. /FEA=mRNA /GEN=CHM-I /PROD=chondromodulin I precursor /DB_XREF=gi:5901931 /UG=Hs.97932 chondromodulin I precursor /FL=gb:AB006000.1 gb:NM_007015.1 NM_007015 leukocyte cell derived chemotaxin 1 LECT1 11061 NM_001011705 /// NM_007015 /// XM_006719760 /// XM_006719761 0001501 // skeletal system development // traceable author statement /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206310_at NM_021114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021114.1 /DEF=Homo sapiens serine protease inhibitor, Kazal type, 2 (acrosin-trypsin inhibitor) (SPINK2), mRNA. /FEA=mRNA /GEN=SPINK2 /PROD=serine protease inhibitor, Kazal type, 2(acrosin-trypsin inhibitor) /DB_XREF=gi:10863910 /UG=Hs.98243 serine protease inhibitor, Kazal type, 2 (acrosin-trypsin inhibitor) /FL=gb:NM_021114.1 NM_021114 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) SPINK2 6691 NM_001271718 /// NM_001271719 /// NM_001271720 /// NM_001271721 /// NM_001271722 /// NM_021114 /// NR_073417 /// NR_073418 /// NR_073419 /// XM_006714050 0002176 // male germ cell proliferation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206311_s_at NM_000928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000928.1 /DEF=Homo sapiens phospholipase A2, group IB (pancreas) (PLA2G1B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PLA2G1B /PROD=phospholipase A2, group IB (pancreas) /DB_XREF=gi:4505846 /UG=Hs.992 phospholipase A2, group IB (pancreas) /FL=gb:M21054.1 gb:NM_000928.1 NM_000928 phospholipase A2, group IB (pancreas) PLA2G1B 5319 NM_000928 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0002446 // neutrophil mediated immunity // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0007015 // actin filament organization // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0032431 // activation of phospholipase A2 activity // traceable author statement /// 0032637 // interleukin-8 production // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044240 // multicellular organismal lipid catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // inferred from direct assay /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred by curator /// 0050482 // arachidonic acid secretion // traceable author statement /// 0050714 // positive regulation of protein secretion // traceable author statement /// 0050778 // positive regulation of immune response // inferred from sequence or structural similarity /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032052 // bile acid binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from direct assay 206312_at NM_004963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004963.1 /DEF=Homo sapiens guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), mRNA. /FEA=mRNA /GEN=GUCY2C /PROD=guanylate cyclase 2C (heat stable enterotoxinreceptor) /DB_XREF=gi:4826751 /UG=Hs.1085 guanylate cyclase 2C (heat stable enterotoxin receptor) /FL=gb:M73489.1 gb:NM_004963.1 NM_004963 guanylate cyclase 2C (heat stable enterotoxin receptor) GUCY2C 2984 NM_004963 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007168 // receptor guanylyl cyclase signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015643 // toxic substance binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation 206313_at NM_002119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002119.1 /DEF=Homo sapiens major histocompatibility complex, class II, DN alpha (HLA-DNA), mRNA. /FEA=mRNA /GEN=HLA-DNA /PROD=major histocompatibility complex, class II, DNalpha /DB_XREF=gi:4504400 /UG=Hs.11135 major histocompatibility complex, class II, DN alpha /FL=gb:M26039.1 gb:M31525.1 gb:NM_002119.1 NM_002119 major histocompatibility complex, class II, DO alpha HLA-DOA 3111 NM_002119 /// XM_005249047 /// XM_005272804 /// XM_005274951 /// XM_005275106 /// XM_005275243 /// XM_005275383 /// XM_005275540 /// XM_006715076 /// XM_006725483 /// XM_006725697 /// XM_006725815 /// XM_006725906 /// XM_006725996 /// XM_006726086 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002587 // negative regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement 206314_at NM_018651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018651.1 /DEF=Homo sapiens zinc finger protein (ZFP), mRNA. /FEA=mRNA /GEN=ZFP /PROD=zinc finger protein /DB_XREF=gi:8924263 /UG=Hs.1148 zinc finger protein /FL=gb:AF154846.1 gb:NM_018651.1 NM_018651 zinc finger with KRAB and SCAN domains 7 ZKSCAN7 55888 NM_001288590 /// NM_001288591 /// NM_001288592 /// NM_018651 /// NM_025169 /// XM_005265323 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206315_at NM_004750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004750.1 /DEF=Homo sapiens cytokine receptor-like factor 1 (CRLF1), mRNA. /FEA=mRNA /GEN=CRLF1 /PROD=cytokine receptor-like factor 1 /DB_XREF=gi:4758061 /UG=Hs.114948 cytokine receptor-like factor 1 /FL=gb:AF059293.1 gb:NM_004750.1 gb:AF073515.1 gb:AF178684.1 NM_004750 cytokine receptor-like factor 1 CRLF1 9244 NM_004750 /// XM_006722934 0001657 // ureteric bud development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 2000672 // negative regulation of motor neuron apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0097058 // CRLF-CLCF1 complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005125 // cytokine activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay 206316_s_at NM_014708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014708.1 /DEF=Homo sapiens KIAA0166 gene product (KIAA0166), mRNA. /FEA=mRNA /GEN=KIAA0166 /PROD=KIAA0166 gene product /DB_XREF=gi:7661959 /UG=Hs.115778 KIAA0166 gene product /FL=gb:D79988.1 gb:NM_014708.1 NM_014708 kinetochore associated 1 KNTC1 9735 NM_014708 /// XM_006719706 /// XR_429122 0000278 // mitotic cell cycle // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007096 // regulation of exit from mitosis // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206317_s_at NM_007188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007188.2 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 8 (ABCB8), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ABCB8 /PROD=ATP-binding cassette, sub-family B, member 8 /DB_XREF=gi:9955964 /UG=Hs.118634 ATP-binding cassette, sub-family B (MDRTAP), member 8 /FL=gb:AF047690.1 gb:NM_007188.2 NM_007188 ATP-binding cassette, sub-family B (MDR/TAP), member 8 ABCB8 11194 NM_001282291 /// NM_001282292 /// NM_001282293 /// NM_007188 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 206318_at NM_020398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020398.1 /DEF=Homo sapiens eppin-3 (EPPIN3), mRNA. /FEA=mRNA /GEN=EPPIN3 /PROD=eppin-3 /DB_XREF=gi:10732862 /UG=Hs.121084 eppin-3 /FL=gb:AF286370.2 gb:NM_020398.1 gb:AF286368.1 NM_020398 epididymal peptidase inhibitor /// EPPIN-WFDC6 readthrough EPPIN /// EPPIN-WFDC6 57119 /// 100526773 NM_001198986 /// NM_020398 /// NM_181502 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206319_s_at AF286368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF286368.1 /DEF=Homo sapiens eppin-1 (EPPIN1) mRNA, complete cds. /FEA=mRNA /GEN=EPPIN1 /PROD=eppin-1 /DB_XREF=gi:9837367 /UG=Hs.121084 eppin-3 /FL=gb:AF286370.2 gb:NM_020398.1 gb:AF286368.1 AF286368 epididymal peptidase inhibitor /// EPPIN-WFDC6 readthrough EPPIN /// EPPIN-WFDC6 57119 /// 100526773 NM_001198986 /// NM_020398 /// NM_181502 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206320_s_at NM_005905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005905.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 9 (MADH9), mRNA. /FEA=mRNA /GEN=MADH9 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 9 /DB_XREF=gi:5174518 /UG=Hs.123119 MAD (mothers against decapentaplegic, Drosophila) homolog 9 /FL=gb:D83761.1 gb:NM_005905.1 NM_005905 SMAD family member 9 SMAD9 4093 NM_001127217 /// NM_005905 /// XM_005266401 /// XM_005266403 /// XM_005266404 /// XM_006719827 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206321_at NM_002918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002918.1 /DEF=Homo sapiens regulatory factor X, 1 (influences HLA class II expression) (RFX1), mRNA. /FEA=mRNA /GEN=RFX1 /PROD=regulatory factor X, 1 (influences HLA class IIexpression) /DB_XREF=gi:4506492 /UG=Hs.123638 regulatory factor X, 1 (influences HLA class II expression) /FL=gb:NM_002918.1 NM_002918 regulatory factor X, 1 (influences HLA class II expression) RFX1 5989 NM_002918 /// XM_006722829 /// XM_006722830 /// XM_006722831 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206322_at NM_003490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003490.1 /DEF=Homo sapiens synapsin III (SYN3), mRNA. /FEA=mRNA /GEN=SYN3 /PROD=synapsin III /DB_XREF=gi:4507332 /UG=Hs.125878 synapsin III /FL=gb:AF046873.1 gb:NM_003490.1 NM_003490 synapsin III SYN3 8224 NM_001135774 /// NM_003490 /// NM_133632 /// NM_133633 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 206323_x_at NM_002547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002547.1 /DEF=Homo sapiens oligophrenin 1 (OPHN1), mRNA. /FEA=mRNA /GEN=OPHN1 /PROD=oligophrenin 1, Rho-GTPase acivating protein /DB_XREF=gi:4505506 /UG=Hs.128824 oligophrenin 1 /FL=gb:NM_002547.1 NM_002547 oligophrenin 1 OPHN1 4983 NM_002547 /// XM_005262270 /// XM_006724652 /// XM_006724653 0006897 // endocytosis // inferred from electronic annotation /// 0006930 // substrate-dependent cell migration, cell extension // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 206324_s_at NM_014326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014326.1 /DEF=Homo sapiens death-associated protein kinase 2 (DAPK2), mRNA. /FEA=mRNA /GEN=DAPK2 /PROD=death-associated protein kinase 2 /DB_XREF=gi:7657004 /UG=Hs.129208 death-associated protein kinase 2 /FL=gb:AF052941.1 gb:AB018001.1 gb:NM_014326.1 NM_014326 death-associated protein kinase 2 DAPK2 23604 NM_014326 /// XM_005254265 /// XM_005254266 /// XM_005254268 /// XM_005254270 /// XM_006720449 /// XM_006720450 /// XM_006720451 /// XM_006720452 /// XM_006720453 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043276 // anoikis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 1900119 // positive regulation of execution phase of apoptosis // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034423 // autophagic vacuole lumen // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 206325_at NM_001756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001756.2 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (SERPINA6), mRNA. /FEA=mRNA /GEN=SERPINA6 /PROD=corticosteroid binding globulin precursor /DB_XREF=gi:4580418 /UG=Hs.1305 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 /FL=gb:J02943.1 gb:NM_001756.2 NM_001756 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 SERPINA6 866 NM_001756 0006810 // transport // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005496 // steroid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 206326_at NM_002091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002091.1 /DEF=Homo sapiens gastrin-releasing peptide (GRP), mRNA. /FEA=mRNA /GEN=GRP /PROD=gastrin-releasing peptide /DB_XREF=gi:4504158 /UG=Hs.1473 gastrin-releasing peptide /FL=gb:BC004488.1 gb:K02054.1 gb:NM_002091.1 NM_002091 gastrin-releasing peptide GRP 2922 NM_001012512 /// NM_001012513 /// NM_002091 /// XM_006722442 0007165 // signal transduction // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005102 // receptor binding // non-traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from direct assay 206327_s_at NM_004933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004933.1 /DEF=Homo sapiens cadherin 15, M-cadherin (myotubule) (CDH15), mRNA. /FEA=mRNA /GEN=CDH15 /PROD=cadherin 15, M-cadherin (myotubule) /DB_XREF=gi:4826668 /UG=Hs.148090 cadherin 15, M-cadherin (myotubule) /FL=gb:D83542.1 gb:NM_004933.1 NM_004933 cadherin 15, type 1, M-cadherin (myotubule) CDH15 1013 NM_004933 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206328_at NM_004933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004933.1 /DEF=Homo sapiens cadherin 15, M-cadherin (myotubule) (CDH15), mRNA. /FEA=mRNA /GEN=CDH15 /PROD=cadherin 15, M-cadherin (myotubule) /DB_XREF=gi:4826668 /UG=Hs.148090 cadherin 15, M-cadherin (myotubule) /FL=gb:D83542.1 gb:NM_004933.1 NM_004933 cadherin 15, type 1, M-cadherin (myotubule) CDH15 1013 NM_004933 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206329_at NM_004455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004455.1 /DEF=Homo sapiens exostoses (multiple)-like 1 (EXTL1), mRNA. /FEA=mRNA /GEN=EXTL1 /PROD=exostoses (multiple)-like 1 /DB_XREF=gi:4758317 /UG=Hs.150956 exostoses (multiple)-like 1 /FL=gb:U67191.1 gb:NM_004455.1 NM_004455 exostosin-like glycosyltransferase 1 EXTL1 2134 NM_004455 /// XM_005245779 /// XM_006710447 /// XM_006710448 0001501 // skeletal system development // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation 206330_s_at NM_016848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016848.1 /DEF=Homo sapiens neuronal Shc (SHC3), mRNA. /FEA=mRNA /GEN=SHC3 /PROD=neuronal Shc /DB_XREF=gi:8394263 /UG=Hs.151123 neuronal Shc /FL=gb:NM_016848.1 NM_016848 SHC (Src homology 2 domain containing) transforming protein 3 SHC3 53358 NM_016848 /// XM_005252052 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206331_at NM_005795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005795.1 /DEF=Homo sapiens calcitonin receptor-like (CALCRL), mRNA. /FEA=mRNA /GEN=CALCRL /PROD=calcitonin receptor-like /DB_XREF=gi:5031620 /UG=Hs.152175 calcitonin receptor-like /FL=gb:L76380.1 gb:NM_005795.1 NM_005795 calcitonin receptor-like CALCRL 10203 NM_001271751 /// NM_005795 /// XM_005246231 /// XM_005246232 /// XM_005246234 0001525 // angiogenesis // inferred from direct assay /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0071329 // cellular response to sucrose stimulus // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001605 // adrenomedullin receptor activity // inferred from direct assay /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004948 // calcitonin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay 206332_s_at NM_005531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005531.1 /DEF=Homo sapiens interferon, gamma-inducible protein 16 (IFI16), mRNA. /FEA=mRNA /GEN=IFI16 /PROD=interferon, gamma-inducible protein 16 /DB_XREF=gi:5031778 /UG=Hs.155530 interferon, gamma-inducible protein 16 /FL=gb:M63838.1 gb:NM_005531.1 NM_005531 interferon, gamma-inducible protein 16 IFI16 3428 NM_001206567 /// NM_005531 /// XM_005245127 /// XM_006711290 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // traceable author statement /// 0002218 // activation of innate immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0010506 // regulation of autophagy // inferred from expression pattern /// 0030097 // hemopoiesis // non-traceable author statement /// 0030099 // myeloid cell differentiation // non-traceable author statement /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032731 // positive regulation of interleukin-1 beta production // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 206333_at NM_002442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002442.1 /DEF=Homo sapiens Musashi (Drosophila) homolog 1 (MSI1), mRNA. /FEA=mRNA /GEN=MSI1 /PROD=Musashi (Drosophila) homolog 1 /DB_XREF=gi:4505254 /UG=Hs.158311 Musashi (Drosophila) homolog 1 /FL=gb:AB012851.1 gb:NM_002442.1 NM_002442 musashi RNA-binding protein 1 MSI1 4440 NM_002442 /// XM_006719403 /// XM_006719404 0007399 // nervous system development // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0008266 // poly(U) RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 206334_at NM_004190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004190.1 /DEF=Homo sapiens lipase, gastric (LIPF), mRNA. /FEA=mRNA /GEN=LIPF /PROD=lipase, gastric /DB_XREF=gi:4758675 /UG=Hs.159177 lipase, gastric /FL=gb:NM_004190.1 NM_004190 lipase, gastric LIPF 8513 NM_001198828 /// NM_001198829 /// NM_001198830 /// NM_004190 0006108 // malate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0004806 // triglyceride lipase activity // traceable author statement /// 0008289 // lipid binding // non-traceable author statement /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 206335_at NM_000512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000512.2 /DEF=Homo sapiens galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA) (GALNS), mRNA. /FEA=mRNA /GEN=GALNS /PROD=N-acetylgalactosamine-6-sulfatase precursor /DB_XREF=gi:9945384 /UG=Hs.159479 galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA) /FL=gb:NM_000512.2 NM_000512 galactosamine (N-acetyl)-6-sulfate sulfatase GALNS 2588 NM_000512 /// XM_005256301 /// XM_005256302 /// XM_005256303 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003943 // N-acetylgalactosamine-4-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043890 // N-acetylgalactosamine-6-sulfatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206336_at NM_002993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002993.1 /DEF=Homo sapiens small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2) (SCYB6), mRNA. /FEA=mRNA /GEN=SCYB6 /PROD=small inducible cytokine subfamily B(Cys-X-Cys), member 6 (granulocyte chemotactic protein 2) /DB_XREF=gi:4506850 /UG=Hs.164021 small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2) /FL=gb:U81234.1 gb:NM_002993.1 NM_002993 chemokine (C-X-C motif) ligand 6 CXCL6 6372 NM_002993 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 206337_at NM_001838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001838.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 7 (CCR7), mRNA. /FEA=mRNA /GEN=CCR7 /PROD=chemokine (C-C motif) receptor 7 /DB_XREF=gi:4502640 /UG=Hs.1652 chemokine (C-C motif) receptor 7 /FL=gb:L08176.1 gb:NM_001838.1 gb:L31581.1 NM_001838 chemokine (C-C motif) receptor 7 CCR7 1236 NM_001838 0001768 // establishment of T cell polarity // inferred by curator /// 0001954 // positive regulation of cell-matrix adhesion // inferred by curator /// 0002407 // dendritic cell chemotaxis // inferred by curator /// 0002408 // myeloid dendritic cell chemotaxis // inferred by curator /// 0002408 // myeloid dendritic cell chemotaxis // inferred from direct assay /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002885 // positive regulation of hypersensitivity // inferred from sequence or structural similarity /// 0002922 // positive regulation of humoral immune response // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred by curator /// 0031274 // positive regulation of pseudopodium assembly // inferred by curator /// 0031529 // ruffle organization // inferred by curator /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032649 // regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032862 // activation of Rho GTPase activity // inferred by curator /// 0034695 // response to prostaglandin E // inferred by curator /// 0038115 // chemokine (C-C motif) ligand 19 signaling pathway // inferred from direct assay /// 0038116 // chemokine (C-C motif) ligand 21 signaling pathway // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred by curator /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred by curator /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred by curator /// 0045860 // positive regulation of protein kinase activity // inferred by curator /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0050706 // regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred by curator /// 0051491 // positive regulation of filopodium assembly // inferred by curator /// 0051897 // positive regulation of protein kinase B signaling // inferred by curator /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred by curator /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 0071731 // response to nitric oxide // inferred by curator /// 0072610 // interleukin-12 secretion // inferred from sequence or structural similarity /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 0097022 // lymphocyte migration into lymph node // traceable author statement /// 0097029 // mature dendritic cell differentiation // inferred from sequence or structural similarity /// 2000107 // negative regulation of leukocyte apoptotic process // inferred by curator /// 2000147 // positive regulation of cell motility // inferred by curator /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from sequence or structural similarity /// 2000522 // positive regulation of immunological synapse formation // inferred from sequence or structural similarity /// 2000525 // positive regulation of T cell costimulation // inferred from sequence or structural similarity /// 2000526 // positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation // inferred from sequence or structural similarity /// 2000547 // regulation of dendritic cell dendrite assembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from sequence or structural similarity /// 0035757 // chemokine (C-C motif) ligand 19 binding // inferred from physical interaction /// 0035758 // chemokine (C-C motif) ligand 21 binding // inferred from physical interaction /// 0038117 // C-C motif chemokine 19 receptor activity // inferred from direct assay /// 0038121 // C-C motif chemokine 21 receptor activity // inferred from direct assay 206338_at NM_001420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001420.2 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) (ELAVL3), mRNA. /FEA=mRNA /GEN=ELAVL3 /PROD=Hu antigen C /DB_XREF=gi:5231299 /UG=Hs.1701 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) /FL=gb:D26158.1 gb:L26405.1 gb:NM_001420.2 NM_001420 ELAV like neuron-specific RNA binding protein 3 ELAVL3 1995 NM_001420 /// NM_032281 /// XM_005259812 /// XM_006722682 /// XM_006722683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay 206339_at NM_004291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004291.1 /DEF=Homo sapiens cocaine- and amphetamine-regulated transcript (CART), mRNA. /FEA=mRNA /GEN=CART /PROD=cocaine- and amphetamine-regulated transcript /DB_XREF=gi:4757909 /UG=Hs.1707 cocaine- and amphetamine-regulated transcript /FL=gb:NM_004291.1 gb:U16826.1 NM_004291 CART prepropeptide CARTPT 9607 NM_004291 0000186 // activation of MAPKK activity // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008343 // adult feeding behavior // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0032099 // negative regulation of appetite // traceable author statement /// 0032812 // positive regulation of epinephrine secretion // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // traceable author statement /// 0045777 // positive regulation of blood pressure // inferred from direct assay /// 0045779 // negative regulation of bone resorption // inferred from mutant phenotype /// 0046850 // regulation of bone remodeling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from direct assay /// 0070093 // negative regulation of glucagon secretion // inferred from electronic annotation /// 0070253 // somatostatin secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206340_at NM_005123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005123.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group H, member 4 (NR1H4), mRNA. /FEA=mRNA /GEN=NR1H4 /PROD=nuclear receptor subfamily 1, group H, member 4 /DB_XREF=gi:4826979 /UG=Hs.171683 nuclear receptor subfamily 1, group H, member 4 /FL=gb:U68233.1 gb:NM_005123.1 NM_005123 nuclear receptor subfamily 1, group H, member 4 NR1H4 9971 NM_001206977 /// NM_001206978 /// NM_001206979 /// NM_001206992 /// NM_001206993 /// NM_005123 /// XM_006719719 /// XR_245969 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001080 // nitrogen catabolite activation of transcription from RNA polymerase II promoter // inferred by curator /// 0006109 // regulation of carbohydrate metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034255 // regulation of urea metabolic process // inferred from sequence or structural similarity /// 0038183 // bile acid signaling pathway // inferred from electronic annotation /// 0038185 // intracellular bile acid receptor signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from electronic annotation /// 0070857 // regulation of bile acid biosynthetic process // traceable author statement /// 0070858 // negative regulation of bile acid biosynthetic process // inferred from direct assay /// 0071229 // cellular response to acid // inferred from direct assay /// 0071417 // cellular response to organonitrogen compound // inferred from sequence or structural similarity /// 0090181 // regulation of cholesterol metabolic process // traceable author statement /// 2000213 // positive regulation of glutamate metabolic process // inferred from sequence or structural similarity /// 2001250 // positive regulation of ammonia assimilation cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // traceable author statement /// 0032052 // bile acid binding // inferred from sequence or structural similarity /// 0032052 // bile acid binding // traceable author statement /// 0038181 // bile acid receptor activity // inferred from direct assay /// 0042277 // peptide binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 1902122 // chenodeoxycholic acid binding // inferred from direct assay 206341_at NM_000417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000417.1 /DEF=Homo sapiens interleukin 2 receptor, alpha (IL2RA), mRNA. /FEA=mRNA /GEN=IL2RA /PROD=interleukin 2 receptor, alpha chain precursor /DB_XREF=gi:4557666 /UG=Hs.1724 interleukin 2 receptor, alpha /FL=gb:NM_000417.1 NM_000417 interleukin 2 receptor, alpha IL2RA 3559 NM_000417 /// XM_005252446 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0038110 // interleukin-2-mediated signaling pathway // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0046013 // regulation of T cell homeostatic proliferation // inferred from electronic annotation /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004911 // interleukin-2 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0019976 // interleukin-2 binding // inferred from electronic annotation 206342_x_at NM_006123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006123.1 /DEF=Homo sapiens iduronate 2-sulfatase (Hunter syndrome) (IDS), transcript variant 2, mRNA. /FEA=mRNA /GEN=IDS /PROD=iduronate-2-sulfatase isoform b precursor /DB_XREF=gi:5360207 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:L40586.1 gb:NM_006123.1 NM_006123 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206343_s_at NM_013959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013959.1 /DEF=Homo sapiens neuregulin 1 (NRG1), transcript variant SMDF, mRNA. /FEA=mRNA /GEN=NRG1 /PROD=neuregulin 1 isoform SMDF /DB_XREF=gi:7669517 /UG=Hs.172816 neuregulin 1 /FL=gb:NM_013959.1 gb:L41827.1 NM_013959 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 206344_at U53784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U53784.1 /DEF=Human serum aryldialkylphosphatase precursor mRNA, complete cds. /FEA=mRNA /PROD=serum aryldialkylphosphatase precursor /DB_XREF=gi:1280040 /UG=Hs.1898 paraoxonase 1 /FL=gb:U53784.1 gb:D84371.1 gb:M63012.1 gb:NM_000446.1 U53784 paraoxonase 1 PON1 5444 NM_000446 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009605 // response to external stimulus // non-traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay /// 0032411 // positive regulation of transporter activity // inferred from direct assay /// 0034445 // negative regulation of plasma lipoprotein particle oxidation // inferred from direct assay /// 0046395 // carboxylic acid catabolic process // inferred from direct assay /// 0046434 // organophosphate catabolic process // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // traceable author statement /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004063 // aryldialkylphosphatase activity // inferred from direct assay /// 0004064 // arylesterase activity // inferred from direct assay /// 0004064 // arylesterase activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016844 // strictosidine synthase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206345_s_at NM_000446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000446.1 /DEF=Homo sapiens paraoxonase 1 (PON1), mRNA. /FEA=mRNA /GEN=PON1 /PROD=paraoxonase 1 /DB_XREF=gi:4505950 /UG=Hs.1898 paraoxonase 1 /FL=gb:U53784.1 gb:D84371.1 gb:M63012.1 gb:NM_000446.1 NM_000446 paraoxonase 1 PON1 5444 NM_000446 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009605 // response to external stimulus // non-traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay /// 0032411 // positive regulation of transporter activity // inferred from direct assay /// 0034445 // negative regulation of plasma lipoprotein particle oxidation // inferred from direct assay /// 0046395 // carboxylic acid catabolic process // inferred from direct assay /// 0046434 // organophosphate catabolic process // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // traceable author statement /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004063 // aryldialkylphosphatase activity // inferred from direct assay /// 0004064 // arylesterase activity // inferred from direct assay /// 0004064 // arylesterase activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016844 // strictosidine synthase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206346_at NM_000949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000949.1 /DEF=Homo sapiens prolactin receptor (PRLR), mRNA. /FEA=mRNA /GEN=PRLR /PROD=prolactin receptor /DB_XREF=gi:4506106 /UG=Hs.1906 prolactin receptor /FL=gb:M31661.1 gb:NM_000949.1 NM_000949 prolactin receptor PRLR 5618 NM_000949 /// NM_001204314 /// NM_001204315 /// NM_001204316 /// NM_001204317 /// NM_001204318 /// NR_037910 /// XM_006714484 0006694 // steroid biosynthetic process // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007566 // embryo implantation // traceable author statement /// 0007595 // lactation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // non-traceable author statement /// 0038161 // prolactin signaling pathway // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042977 // activation of JAK2 kinase activity // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004925 // prolactin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042978 // ornithine decarboxylase activator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206347_at NM_005391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005391.1 /DEF=Homo sapiens pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3), mRNA. /FEA=mRNA /GEN=PDK3 /PROD=pyruvate dehydrogenase kinase, isoenzyme 3 /DB_XREF=gi:4885544 /UG=Hs.193124 pyruvate dehydrogenase kinase, isoenzyme 3 /FL=gb:L42452.1 gb:NM_005391.1 NM_005391 pyruvate dehydrogenase kinase, isozyme 3 PDK3 5165 NM_001142386 /// NM_005391 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from mutant phenotype /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071398 // cellular response to fatty acid // inferred from mutant phenotype /// 0097411 // hypoxia-inducible factor-1alpha signaling pathway // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206348_s_at NM_005391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005391.1 /DEF=Homo sapiens pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3), mRNA. /FEA=mRNA /GEN=PDK3 /PROD=pyruvate dehydrogenase kinase, isoenzyme 3 /DB_XREF=gi:4885544 /UG=Hs.193124 pyruvate dehydrogenase kinase, isoenzyme 3 /FL=gb:L42452.1 gb:NM_005391.1 NM_005391 pyruvate dehydrogenase kinase, isozyme 3 PDK3 5165 NM_001142386 /// NM_005391 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from mutant phenotype /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071398 // cellular response to fatty acid // inferred from mutant phenotype /// 0097411 // hypoxia-inducible factor-1alpha signaling pathway // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206349_at NM_005097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005097.1 /DEF=Homo sapiens leucine-rich, glioma inactivated 1 (LGI1), mRNA. /FEA=mRNA /GEN=LGI1 /PROD=leucine-rich, glioma inactivated 1 precursor /DB_XREF=gi:4826815 /UG=Hs.194704 leucine-rich, glioma inactivated 1 /FL=gb:AF055636.1 gb:NM_005097.1 NM_005097 leucine-rich, glioma inactivated 1 LGI1 9211 NM_005097 /// XM_005270272 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from mutant phenotype /// 0008283 // cell proliferation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0050806 // positive regulation of synaptic transmission // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 206350_at NM_001639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001639.1 /DEF=Homo sapiens amyloid P component, serum (APCS), mRNA. /FEA=mRNA /GEN=APCS /PROD=amyloid P component, serum /DB_XREF=gi:4502132 /UG=Hs.1957 amyloid P component, serum /FL=gb:M10944.1 gb:NM_001639.1 NM_001639 amyloid P component, serum APCS 325 NM_001639 0002674 // negative regulation of acute inflammatory response // inferred by curator /// 0006457 // protein folding // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006953 // acute-phase response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045656 // negative regulation of monocyte differentiation // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051131 // chaperone-mediated protein complex assembly // traceable author statement /// 0061045 // negative regulation of wound healing // inferred by curator /// 1903016 // negative regulation of exo-alpha-sialidase activity // inferred from direct assay /// 1903019 // negative regulation of glycoprotein metabolic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0046790 // virion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 206351_s_at NM_002617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002617.1 /DEF=Homo sapiens peroxisome biogenesis factor 10 (PEX10), mRNA. /FEA=mRNA /GEN=PEX10 /PROD=peroxisome biogenesis factor 10 /DB_XREF=gi:4505714 /UG=Hs.247220 peroxisome biogenesis factor 10 /FL=gb:AF060502.1 gb:NM_002617.1 gb:AB013818.1 NM_002617 peroxisomal biogenesis factor 10 PEX10 5192 NM_002617 /// NM_153818 0007031 // peroxisome organization // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype 0005622 // intracellular // inferred from mutant phenotype /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206352_s_at AB013818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013818.1 /DEF=Homo sapiens PEX10 mRNA for peroxisome biogenesis factor (peroxin) 10, complete cds. /FEA=mRNA /GEN=PEX10 /PROD=peroxisome biogenesis factor (peroxin) 10 /DB_XREF=gi:6518430 /UG=Hs.247220 peroxisome biogenesis factor 10 /FL=gb:AF060502.1 gb:NM_002617.1 gb:AB013818.1 AB013818 peroxisomal biogenesis factor 10 PEX10 5192 NM_002617 /// NM_153818 0007031 // peroxisome organization // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype 0005622 // intracellular // inferred from mutant phenotype /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206353_at NM_005205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005205.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIa polypeptide 2 (COX6A2), mRNA. /FEA=mRNA /GEN=COX6A2 /PROD=cytochrome c oxidase subunit VIa polypeptide 2 /DB_XREF=gi:4885148 /UG=Hs.250760 cytochrome c oxidase subunit VIa polypeptide 2 /FL=gb:M83308.1 gb:NM_005205.1 NM_005205 cytochrome c oxidase subunit VIa polypeptide 2 COX6A2 1339 NM_005205 0006091 // generation of precursor metabolites and energy // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005751 // mitochondrial respiratory chain complex IV // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 206354_at NM_019844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019844.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 8 (SLC21A8), mRNA. /FEA=mRNA /GEN=SLC21A8 /PROD=solute carrier family 21 (organic aniontransporter), member 8 /DB_XREF=gi:9790232 /UG=Hs.274981 solute carrier family 21 (organic anion transporter), member 8 /FL=gb:AF187815.1 gb:NM_019844.1 NM_019844 solute carrier organic anion transporter family, member 1B3 SLCO1B3 28234 NM_019844 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement 206355_at R20102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R20102 /FEA=EST /DB_XREF=gi:774736 /DB_XREF=est:yg39h06.r1 /CLONE=IMAGE:35031 /UG=Hs.288642 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type /FL=gb:L10665.1 gb:NM_002071.1 R20102 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type GNAL 2774 NM_001142339 /// NM_001261443 /// NM_001261444 /// NM_002071 /// NM_182978 /// XM_006722323 /// XM_006722324 /// XR_243798 0001975 // response to amphetamine // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // not recorded /// 0031000 // response to caffeine // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 206356_s_at NM_002071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002071.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), mRNA. /FEA=mRNA /GEN=GNAL /PROD=guanine nucleotide binding protein (G protein),alpha activating activity polypeptide, olfactory type /DB_XREF=gi:4504042 /UG=Hs.288642 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type /FL=gb:L10665.1 gb:NM_002071.1 NM_002071 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type GNAL 2774 NM_001142339 /// NM_001261443 /// NM_001261444 /// NM_002071 /// NM_182978 /// XM_006722323 /// XM_006722324 /// XR_243798 0001975 // response to amphetamine // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // not recorded /// 0031000 // response to caffeine // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 206357_at NM_025136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025136.1 /DEF=Homo sapiens hypothetical protein FLJ22187 (FLJ22187), mRNA. /FEA=mRNA /GEN=FLJ22187 /PROD=hypothetical protein FLJ22187 /DB_XREF=gi:13376716 /UG=Hs.288842 hypothetical protein FLJ22187 /FL=gb:NM_025136.1 gb:BC005059.1 NM_025136 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) OPA3 80207 NM_001017989 /// NM_025136 /// XM_005259278 /// XM_006723403 0007601 // visual perception // inferred from mutant phenotype /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 206358_at NM_002761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002761.1 /DEF=Homo sapiens protamine 1 (PRM1), mRNA. /FEA=mRNA /GEN=PRM1 /PROD=protamine 1 /DB_XREF=gi:4506108 /UG=Hs.2909 protamine 1 /FL=gb:BC003673.1 gb:NM_002761.1 NM_002761 protamine 1 PRM1 5619 NM_002761 0006323 // DNA packaging // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 206359_at BG035761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG035761 /FEA=EST /DB_XREF=gi:12430218 /DB_XREF=est:602325844F1 /CLONE=IMAGE:4413754 /UG=Hs.296176 STAT induced STAT inhibitor 3 /FL=gb:AB004904.1 gb:AB006967.1 gb:NM_003955.1 gb:AF159854.1 BG035761 suppressor of cytokine signaling 3 SOCS3 9021 NM_003955 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206360_s_at NM_003955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003955.1 /DEF=Homo sapiens STAT induced STAT inhibitor 3 (SSI-3), mRNA. /FEA=mRNA /GEN=SSI-3 /PROD=STAT induced STAT inhibitor 3 /DB_XREF=gi:4507234 /UG=Hs.296176 STAT induced STAT inhibitor 3 /FL=gb:AB004904.1 gb:AB006967.1 gb:NM_003955.1 gb:AF159854.1 NM_003955 suppressor of cytokine signaling 3 SOCS3 9021 NM_003955 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206361_at NM_004778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004778.1 /DEF=Homo sapiens G protein-coupled receptor 44 (GPR44), mRNA. /FEA=mRNA /GEN=GPR44 /PROD=G protein-coupled receptor 44 /DB_XREF=gi:4758069 /UG=Hs.299567 G protein-coupled receptor 44 /FL=gb:AB008535.1 gb:NM_004778.1 gb:AF144308.1 NM_004778 prostaglandin D2 receptor 2 PTGDR2 11251 NM_004778 0006935 // chemotaxis // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001785 // prostaglandin J receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0004956 // prostaglandin D receptor activity // inferred from direct assay /// 0004958 // prostaglandin F receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 206362_x_at NM_002446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002446.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 10 (MAP3K10), mRNA. /FEA=mRNA /GEN=MAP3K10 /PROD=mitogen-activated protein kinase kinase kinase10 /DB_XREF=gi:4505262 /UG=Hs.30223 mitogen-activated protein kinase kinase kinase 10 /FL=gb:NM_002446.1 NM_002446 mitogen-activated protein kinase kinase kinase 10 MAP3K10 4294 NM_002446 /// XM_005258948 /// XM_005258949 /// XM_006723222 /// XM_006723223 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0007254 // JNK cascade // traceable author statement /// 0007256 // activation of JNKK activity // inferred from sequence or structural similarity /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004706 // JUN kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043425 // bHLH transcription factor binding // inferred from physical interaction 206363_at NM_005360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005360.2 /DEF=Homo sapiens v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog (MAF), mRNA. /FEA=mRNA /GEN=MAF /PROD=v-maf musculoaponeurotic fibrosarcoma (avian)oncogene homolog /DB_XREF=gi:5453735 /UG=Hs.30250 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog /FL=gb:AF055377.1 gb:NM_005360.2 NM_005360 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog MAF 4094 NM_001031804 /// NM_005360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206364_at NM_014875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014875.1 /DEF=Homo sapiens KIAA0042 gene product (KIAA0042), mRNA. /FEA=mRNA /GEN=KIAA0042 /PROD=KIAA0042 gene product /DB_XREF=gi:7661877 /UG=Hs.3104 KIAA0042 gene product /FL=gb:D26361.1 gb:NM_014875.1 NM_014875 kinesin family member 14 KIF14 9928 NM_014875 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0032487 // regulation of Rap protein signal transduction // inferred from mutant phenotype /// 0033624 // negative regulation of integrin activation // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay 206365_at NM_002995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002995.1 /DEF=Homo sapiens small inducible cytokine subfamily C, member 1 (lymphotactin) (SCYC1), mRNA. /FEA=mRNA /GEN=SCYC1 /PROD=small inducible cytokine subfamily C, member 1(lymphotactin) /DB_XREF=gi:4506852 /UG=Hs.3195 small inducible cytokine subfamily C, member 1 (lymphotactin) /FL=gb:NM_002995.1 gb:U23772.1 gb:D43768.1 NM_002995 chemokine (C motif) ligand 1 XCL1 6375 NM_002995 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from sequence or structural similarity /// 0002725 // negative regulation of T cell cytokine production // inferred from direct assay /// 0002726 // positive regulation of T cell cytokine production // inferred from sequence or structural similarity /// 0002826 // negative regulation of T-helper 1 type immune response // inferred by curator /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred by curator /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035782 // mature natural killer cell chemotaxis // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from sequence or structural similarity /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay /// 0071663 // positive regulation of granzyme B production // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity /// 2000412 // positive regulation of thymocyte migration // inferred from sequence or structural similarity /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay /// 2000513 // positive regulation of granzyme A production // inferred from direct assay /// 2000518 // negative regulation of T-helper 1 cell activation // inferred from direct assay /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity /// 2000556 // positive regulation of T-helper 1 cell cytokine production // inferred from sequence or structural similarity /// 2000558 // positive regulation of immunoglobulin production in mucosal tissue // inferred from sequence or structural similarity /// 2000562 // negative regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 2000566 // positive regulation of CD8-positive, alpha-beta T cell proliferation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from direct assay /// 0042379 // chemokine receptor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 206366_x_at U23772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U23772.1 /DEF=Human lymphotactin precursor mRNA, complete cds. /FEA=mRNA /PROD=lymphotactin precursor /DB_XREF=gi:902001 /UG=Hs.3195 small inducible cytokine subfamily C, member 1 (lymphotactin) /FL=gb:NM_002995.1 gb:U23772.1 gb:D43768.1 U23772 chemokine (C motif) ligand 1 XCL1 6375 NM_002995 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from sequence or structural similarity /// 0002725 // negative regulation of T cell cytokine production // inferred from direct assay /// 0002726 // positive regulation of T cell cytokine production // inferred from sequence or structural similarity /// 0002826 // negative regulation of T-helper 1 type immune response // inferred by curator /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred by curator /// 0007267 // cell-cell signaling // inferred from direct assay /// 0008015 // blood circulation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035782 // mature natural killer cell chemotaxis // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from sequence or structural similarity /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay /// 0071663 // positive regulation of granzyme B production // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity /// 2000412 // positive regulation of thymocyte migration // inferred from sequence or structural similarity /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay /// 2000513 // positive regulation of granzyme A production // inferred from direct assay /// 2000518 // negative regulation of T-helper 1 cell activation // inferred from direct assay /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity /// 2000556 // positive regulation of T-helper 1 cell cytokine production // inferred from sequence or structural similarity /// 2000558 // positive regulation of immunoglobulin production in mucosal tissue // inferred from sequence or structural similarity /// 2000562 // negative regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 2000566 // positive regulation of CD8-positive, alpha-beta T cell proliferation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from direct assay /// 0042379 // chemokine receptor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 206367_at NM_000537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000537.2 /DEF=Homo sapiens renin (REN), mRNA. /FEA=mRNA /GEN=REN /PROD=renin precursor /DB_XREF=gi:11125774 /UG=Hs.3210 renin /FL=gb:NM_000537.2 NM_000537 renin REN 5972 NM_000537 0001822 // kidney development // inferred from mutant phenotype /// 0001823 // mesonephros development // inferred from electronic annotation /// 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0002016 // regulation of blood volume by renin-angiotensin // inferred from electronic annotation /// 0002018 // renin-angiotensin regulation of aldosterone production // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048469 // cell maturation // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0070305 // response to cGMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 206368_at NM_006650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006650.1 /DEF=Homo sapiens complexin 2 (CPLX2), mRNA. /FEA=mRNA /GEN=CPLX2 /PROD=complexin 2 /DB_XREF=gi:5729782 /UG=Hs.321567 complexin 2 /FL=gb:U35100.1 gb:NM_006650.1 NM_006650 complexin 2 CPLX2 10814 NM_001008220 /// NM_006650 /// XM_005265798 /// XM_005265799 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031915 // positive regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0043303 // mast cell degranulation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070033 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation 206369_s_at AF327656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF327656.1 /DEF=Homo sapiens phosphoinositide-3-kinase gamma catalytic subunit (PI3CG) mRNA, complete cds. /FEA=mRNA /GEN=PI3CG /PROD=phosphoinositide-3-kinase gamma catalyticsubunit /DB_XREF=gi:12620870 /UG=Hs.32942 phosphoinositide-3-kinase, catalytic, gamma polypeptide /FL=gb:AF327656.1 gb:NM_002649.1 AF327656 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma PIK3CG 5294 NM_001282426 /// NM_001282427 /// NM_002649 /// XM_005250443 /// XM_006716027 0001525 // angiogenesis // inferred from electronic annotation /// 0001816 // cytokine production // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010818 // T cell chemotaxis // traceable author statement /// 0010897 // negative regulation of triglyceride catabolic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // traceable author statement /// 0035747 // natural killer cell chemotaxis // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0042098 // T cell proliferation // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043303 // mast cell degranulation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055118 // negative regulation of cardiac muscle contraction // traceable author statement /// 0070527 // platelet aggregation // traceable author statement /// 0072672 // neutrophil extravasation // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0005944 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042629 // mast cell granule // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 206370_at NM_002649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002649.1 /DEF=Homo sapiens phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG), mRNA. /FEA=mRNA /GEN=PIK3CG /PROD=phosphoinositide-3-kinase, catalytic, gammapolypeptide /DB_XREF=gi:4505802 /UG=Hs.32942 phosphoinositide-3-kinase, catalytic, gamma polypeptide /FL=gb:AF327656.1 gb:NM_002649.1 NM_002649 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma PIK3CG 5294 NM_001282426 /// NM_001282427 /// NM_002649 /// XM_005250443 /// XM_006716027 0001525 // angiogenesis // inferred from electronic annotation /// 0001816 // cytokine production // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010818 // T cell chemotaxis // traceable author statement /// 0010897 // negative regulation of triglyceride catabolic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // traceable author statement /// 0035747 // natural killer cell chemotaxis // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0042098 // T cell proliferation // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043303 // mast cell degranulation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055118 // negative regulation of cardiac muscle contraction // traceable author statement /// 0070527 // platelet aggregation // traceable author statement /// 0072672 // neutrophil extravasation // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0005944 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042629 // mast cell granule // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 206371_at NM_000804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000804.2 /DEF=Homo sapiens folate receptor 3 (gamma) (FOLR3), mRNA. /FEA=mRNA /GEN=FOLR3 /PROD=folate receptor 3 precursor /DB_XREF=gi:9257219 /UG=Hs.352 folate receptor 3 (gamma) /FL=gb:U08470.1 gb:U08471.1 gb:NM_000804.2 NM_000804 folate receptor 3 (gamma) FOLR3 2352 NM_000804 0015884 // folic acid transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0019898 // extrinsic component of membrane // traceable author statement 0005542 // folic acid binding // inferred from electronic annotation 206372_at NM_002469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002469.1 /DEF=Homo sapiens myogenic factor 6 (herculin) (MYF6), mRNA. /FEA=mRNA /GEN=MYF6 /PROD=myogenic factor 6 (herculin) /DB_XREF=gi:4505298 /UG=Hs.35937 myogenic factor 6 (herculin) /FL=gb:NM_002469.1 NM_002469 myogenic factor 6 (herculin) MYF6 4618 NM_002469 0001756 // somitogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 206373_at NM_003412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003412.1 /DEF=Homo sapiens Zic family member 1 (odd-paired Drosophila homolog) (ZIC1), mRNA. /FEA=mRNA /GEN=ZIC1 /PROD=Zic family member 1 (odd-paired Drosophilahomolog) /DB_XREF=gi:4507970 /UG=Hs.41154 Zic family member 1 (odd-paired Drosophila homolog) /FL=gb:D76435.1 gb:NM_003412.1 NM_003412 Zic family member 1 ZIC1 7545 NM_003412 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from direct assay /// 0007610 // behavior // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206374_at NM_004420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004420.1 /DEF=Homo sapiens dual specificity phosphatase 8 (DUSP8), mRNA. /FEA=mRNA /GEN=DUSP8 /PROD=dual specificity phosphatase 8 /DB_XREF=gi:4758211 /UG=Hs.41688 dual specificity phosphatase 8 /FL=gb:U27193.1 gb:NM_004420.1 NM_004420 dual specificity phosphatase 8 /// putative uncharacterized protein C11orf81-like DUSP8 /// LOC101927562 1850 /// 101927562 NM_004420 /// XM_005253274 /// XM_006725124 /// XM_006725533 0000188 // inactivation of MAPK activity // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 206375_s_at NM_006308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006308.1 /DEF=Homo sapiens heat shock 27kD protein 3 (HSPB3), mRNA. /FEA=mRNA /GEN=HSPB3 /PROD=heat shock 27kD protein 3 /DB_XREF=gi:5453687 /UG=Hs.41707 heat shock 27kD protein 3 /FL=gb:NM_006308.1 NM_006308 heat shock 27kDa protein 3 HSPB3 8988 NM_006308 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 206376_at NM_018057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018057.1 /DEF=Homo sapiens hypothetical protein FLJ10316 (FLJ10316), mRNA. /FEA=mRNA /GEN=FLJ10316 /PROD=hypothetical protein FLJ10316 /DB_XREF=gi:8922349 /UG=Hs.44424 homolog of rat orphan transporter v7-3 /FL=gb:AF265577.1 gb:NM_018057.1 NM_018057 solute carrier family 6 (neutral amino acid transporter), member 15 SLC6A15 55117 NM_001146335 /// NM_018057 /// NM_182767 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // non-traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015804 // neutral amino acid transport // inferred from direct assay /// 0015820 // leucine transport // inferred from sequence or structural similarity /// 0015824 // proline transport // inferred from sequence or structural similarity /// 0035524 // proline transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005298 // proline:sodium symporter activity // inferred from electronic annotation /// 0005326 // neurotransmitter transporter activity // non-traceable author statement /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 206377_at NM_001452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001452.1 /DEF=Homo sapiens forkhead box F2 (FOXF2), mRNA. /FEA=mRNA /GEN=FOXF2 /PROD=forkhead box F2 /DB_XREF=gi:4557594 /UG=Hs.44481 forkhead box F2 /FL=gb:U13220.1 gb:NM_001452.1 NM_001452 forkhead box F2 FOXF2 2295 NM_001452 0001837 // epithelial to mesenchymal transition // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0042249 // establishment of planar polarity of embryonic epithelium // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206378_at NM_002411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002411.1 /DEF=Homo sapiens mammaglobin 1 (MGB1), mRNA. /FEA=mRNA /GEN=MGB1 /PROD=mammaglobin 1 /DB_XREF=gi:4505168 /UG=Hs.46452 mammaglobin 1 /FL=gb:U33147.1 gb:NM_002411.1 NM_002411 secretoglobin, family 2A, member 2 SCGB2A2 4250 NM_002411 /// XM_005274005 0005496 // steroid binding // inferred from electronic annotation 206379_at NM_001990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001990.1 /DEF=Homo sapiens eyes absent (Drosophila) homolog 3 (EYA3), mRNA. /FEA=mRNA /GEN=EYA3 /PROD=eyes absent (Drosophila) homolog 3 /DB_XREF=gi:4503620 /UG=Hs.46925 eyes absent (Drosophila) homolog 3 /FL=gb:U81602.1 gb:NM_001990.1 NM_001990 EYA transcriptional coactivator and phosphatase 3 EYA3 2140 NM_001282560 /// NM_001282561 /// NM_001282562 /// NM_001990 /// NM_172098 /// NR_104214 /// XM_006710449 /// XM_006710450 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206380_s_at NM_002621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002621.1 /DEF=Homo sapiens properdin P factor, complement (PFC), mRNA. /FEA=mRNA /GEN=PFC /PROD=properdin P factor, complement /DB_XREF=gi:4505736 /UG=Hs.53155 properdin P factor, complement /FL=gb:NM_002621.1 gb:M83652.1 NM_002621 complement factor properdin CFP 5199 NM_001145252 /// NM_002621 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 206381_at NM_021007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021007.1 /DEF=Homo sapiens sodium channel, voltage-gated, type II, alpha 2 polypeptide (SCN2A2), mRNA. /FEA=mRNA /GEN=SCN2A2 /PROD=sodium channel, voltage-gated, type II, alpha 2polypeptide /DB_XREF=gi:10337596 /UG=Hs.54499 sodium channel, voltage-gated, type II, alpha 2 polypeptide /FL=gb:NM_021007.1 gb:M94055.1 NM_021007 sodium channel, voltage-gated, type II, alpha subunit SCN2A 6326 NM_001040142 /// NM_001040143 /// NM_021007 /// XM_005246750 /// XM_005246751 /// XM_005246753 /// XM_005246754 /// XM_005246755 /// XM_005246756 0001508 // action potential // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008627 // intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from electronic annotation /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0030424 // axon // traceable author statement /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0034706 // sodium channel complex // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005248 // voltage-gated sodium channel activity // inferred from sequence or structural similarity /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206382_s_at NM_001709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001709.1 /DEF=Homo sapiens brain-derived neurotrophic factor (BDNF), mRNA. /FEA=mRNA /GEN=BDNF /PROD=brain-derived neurotrophic factor /DB_XREF=gi:4502392 /UG=Hs.56023 brain-derived neurotrophic factor /FL=gb:NM_001709.1 NM_001709 brain-derived neurotrophic factor BDNF 627 NM_001143805 /// NM_001143806 /// NM_001143807 /// NM_001143808 /// NM_001143809 /// NM_001143810 /// NM_001143811 /// NM_001143812 /// NM_001143813 /// NM_001143814 /// NM_001143815 /// NM_001143816 /// NM_001709 /// NM_170731 /// NM_170732 /// NM_170733 /// NM_170734 /// NM_170735 0001657 // ureteric bud development // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008038 // neuron recognition // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014076 // response to fluoxetine // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation /// 0046668 // regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0072347 // response to anesthetic // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from electronic annotation /// 0005169 // neurotrophin TRKB receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206383_s_at NM_012297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012297.1 /DEF=Homo sapiens Ras-GTPase activating protein SH3 domain-binding protein 2 (KIAA0660), mRNA. /FEA=mRNA /GEN=KIAA0660 /PROD=Ras-GTPase activating protein SH3 domain-bindingprotein 2 /DB_XREF=gi:7110662 /UG=Hs.6727 Ras-GTPase activating protein SH3 domain-binding protein 2 /FL=gb:AF051311.1 gb:AF053535.1 gb:NM_012297.1 NM_012297 GTPase activating protein (SH3 domain) binding protein 2 G3BP2 9908 NM_012297 /// NM_203504 /// NM_203505 /// XM_005263382 /// XM_005263383 /// XM_005263384 /// XM_005263385 /// XM_005263386 0006810 // transport // inferred from electronic annotation /// 0007253 // cytoplasmic sequestering of NF-kappaB // non-traceable author statement /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 206384_at NM_006539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006539.1 /DEF=Homo sapiens calcium channel, voltage-dependent, gamma subunit 3 (CACNG3), mRNA. /FEA=mRNA /GEN=CACNG3 /PROD=calcium channel, voltage-dependent, gammasubunit 3 /DB_XREF=gi:5729755 /UG=Hs.7235 calcium channel, voltage-dependent, gamma subunit 3 /FL=gb:AF100346.1 gb:NM_006539.1 gb:AF134640.1 NM_006539 calcium channel, voltage-dependent, gamma subunit 3 CACNG3 10368 NM_006539 /// XM_005255037 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // non-traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation 206385_s_at NM_020987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020987.1 /DEF=Homo sapiens ankyrin 3, node of Ranvier (ankyrin G) (ANK3), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANK3 /PROD=ankyrin 3, isoform 1 /DB_XREF=gi:10947055 /UG=Hs.75893 ankyrin 3, node of Ranvier (ankyrin G) /FL=gb:NM_020987.1 gb:U13616.1 NM_020987 ankyrin 3, node of Ranvier (ankyrin G) ANK3 288 NM_001149 /// NM_001204403 /// NM_001204404 /// NM_020987 /// XM_005269715 /// XM_005269716 /// XM_006717782 /// XM_006717783 /// XM_006717784 /// XM_006717785 /// XM_006717786 /// XM_006717787 /// XM_006717788 /// XM_006717789 /// XM_006717790 /// XM_006717791 /// XM_006717792 /// XM_006717793 /// XM_006717794 /// XM_006717795 /// XM_006717796 /// XM_006717797 /// XM_006717798 /// XM_006717799 /// XM_006717800 /// XM_006717801 /// XM_006717802 /// XM_006717803 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010650 // positive regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045838 // positive regulation of membrane potential // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072660 // maintenance of protein location in plasma membrane // inferred from genetic interaction /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 1900827 // positive regulation of membrane depolarization during cardiac muscle cell action potential // inferred from sequence or structural similarity /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0014731 // spectrin-associated cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from sequence or structural similarity /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from sequence or structural similarity 206386_at NM_000354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000354.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (SERPINA7), mRNA. /FEA=mRNA /GEN=SERPINA7 /PROD=serine (or cysteine) proteinase inhibitor, cladeA (alpha-1 antiproteinase, antitrypsin), member 7 /DB_XREF=gi:4507376 /UG=Hs.76838 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 /FL=gb:M14091.1 gb:NM_000354.1 NM_000354 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 SERPINA7 6906 NM_000354 /// XM_005262180 /// XM_006724683 0007568 // aging // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034695 // response to prostaglandin E // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0070327 // thyroid hormone transport // inferred from mutant phenotype 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0042562 // hormone binding // inferred from electronic annotation 206387_at U51096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U51096.1 /DEF=Human homeobox protein Cdx2 mRNA, complete cds. /FEA=mRNA /PROD=homeobox protein Cdx2 /DB_XREF=gi:1777773 /UG=Hs.77399 caudal type homeo box transcription factor 2 /FL=gb:U51096.1 gb:NM_001265.1 U51096 caudal type homeobox 2 CDX2 1045 NM_001265 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206388_at U36798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36798.1 /DEF=Homo sapiens platelet cGI-PDE mRNA, complete cds. /FEA=mRNA /PROD=platelet cGI-PDE /DB_XREF=gi:1039473 /UG=Hs.777 phosphodiesterase 3A, cGMP-inhibited /FL=gb:U36798.1 gb:M91667.1 gb:NM_000921.1 U36798 phosphodiesterase 3A, cGMP-inhibited PDE3A 5139 NM_000921 /// NM_001244683 /// XM_006719086 /// XM_006719087 0001556 // oocyte maturation // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from mutant phenotype /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from mutant phenotype /// 0043117 // positive regulation of vascular permeability // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060282 // positive regulation of oocyte development // inferred from electronic annotation /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004119 // cGMP-inhibited cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206389_s_at NM_000921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000921.1 /DEF=Homo sapiens phosphodiesterase 3A, cGMP-inhibited (PDE3A), mRNA. /FEA=mRNA /GEN=PDE3A /PROD=phosphodiesterase 3A, cGMP-inhibited /DB_XREF=gi:4505658 /UG=Hs.777 phosphodiesterase 3A, cGMP-inhibited /FL=gb:U36798.1 gb:M91667.1 gb:NM_000921.1 NM_000921 phosphodiesterase 3A, cGMP-inhibited PDE3A 5139 NM_000921 /// NM_001244683 /// XM_006719086 /// XM_006719087 0001556 // oocyte maturation // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from mutant phenotype /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from mutant phenotype /// 0043117 // positive regulation of vascular permeability // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060282 // positive regulation of oocyte development // inferred from electronic annotation /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004119 // cGMP-inhibited cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206390_x_at NM_002619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002619.1 /DEF=Homo sapiens platelet factor 4 (PF4), mRNA. /FEA=mRNA /GEN=PF4 /PROD=platelet factor 4 /DB_XREF=gi:4505732 /UG=Hs.81564 platelet factor 4 /FL=gb:M25897.1 gb:NM_002619.1 NM_002619 platelet factor 4 PF4 5196 NM_002619 /// XM_005265696 0002576 // platelet degranulation // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030595 // leukocyte chemotaxis // inferred from direct assay /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from direct assay /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0045918 // negative regulation of cytolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred by curator /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008201 // heparin binding // inferred from direct assay /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 206391_at NM_002888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002888.1 /DEF=Homo sapiens retinoic acid receptor responder (tazarotene induced) 1 (RARRES1), mRNA. /FEA=mRNA /GEN=RARRES1 /PROD=retinoic acid receptor responder (tazaroteneinduced) 1 /DB_XREF=gi:4506424 /UG=Hs.82547 retinoic acid receptor responder (tazarotene induced) 1 /FL=gb:NM_002888.1 gb:U27185.1 NM_002888 retinoic acid receptor responder (tazarotene induced) 1 RARRES1 5918 NM_002888 /// NM_206963 /// XM_005247686 0008285 // negative regulation of cell proliferation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 206392_s_at NM_002888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002888.1 /DEF=Homo sapiens retinoic acid receptor responder (tazarotene induced) 1 (RARRES1), mRNA. /FEA=mRNA /GEN=RARRES1 /PROD=retinoic acid receptor responder (tazaroteneinduced) 1 /DB_XREF=gi:4506424 /UG=Hs.82547 retinoic acid receptor responder (tazarotene induced) 1 /FL=gb:NM_002888.1 gb:U27185.1 NM_002888 retinoic acid receptor responder (tazarotene induced) 1 RARRES1 5918 NM_002888 /// NM_206963 /// XM_005247686 0008285 // negative regulation of cell proliferation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 206393_at NM_003282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003282.1 /DEF=Homo sapiens troponin I, skeletal, fast (TNNI2), mRNA. /FEA=mRNA /GEN=TNNI2 /PROD=troponin I, skeletal, fast /DB_XREF=gi:4507620 /UG=Hs.83760 troponin I, skeletal, fast /FL=gb:NM_003282.1 gb:L21715.1 NM_003282 troponin I type 2 (skeletal, fast) TNNI2 7136 NM_001145829 /// NM_001145841 /// NM_003282 0003009 // skeletal muscle contraction // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031014 // troponin T binding // inferred from physical interaction 206394_at NM_004533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004533.1 /DEF=Homo sapiens myosin-binding protein C, fast-type (MYBPC2), mRNA. /FEA=mRNA /GEN=MYBPC2 /PROD=myosin-binding protein C, fast-type /DB_XREF=gi:4758747 /UG=Hs.85937 myosin-binding protein C, fast-type /FL=gb:NM_004533.1 NM_004533 myosin binding protein C, fast type MYBPC2 4606 NM_004533 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement 0005829 // cytosol // traceable author statement /// 0032982 // myosin filament // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 206395_at NM_001346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001346.1 /DEF=Homo sapiens diacylglycerol kinase, gamma (90kD) (DGKG), mRNA. /FEA=mRNA /GEN=DGKG /PROD=diacylglycerol kinase, gamma (90kD) /DB_XREF=gi:4503314 /UG=Hs.89462 diacylglycerol kinase, gamma (90kD) /FL=gb:NM_001346.1 gb:D26135.1 NM_001346 diacylglycerol kinase, gamma 90kDa DGKG 1608 NM_001080744 /// NM_001080745 /// NM_001346 0007165 // signal transduction // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206396_at NM_004170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004170.1 /DEF=Homo sapiens solute carrier family 1 (neuronalepithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC1A1 /PROD=solute carrier family 1 (neuronalepithelialhigh affinity glutamate transporter, system Xag), member1 /DB_XREF=gi:4759121 /UG=Hs.91139 solute carrier family 1 (neuronalepithelial high affinity glutamate transporter, system Xag), member 1 /FL=gb:NM_004170.1 gb:U03506.1 gb:U08989.1 gb:U06469.1 NM_004170 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 SLC1A1 6505 NM_004170 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015501 // glutamate:sodium symporter activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 206397_x_at NM_001492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001492.3 /DEF=Homo sapiens growth differentiation factor 1 (GDF1), mRNA. /FEA=mRNA /GEN=GDF1 /PROD=growth differentiation factor 1 /DB_XREF=gi:11641419 /UG=Hs.92614 growth differentiation factor 1 /FL=gb:NM_001492.3 NM_001492 ceramide synthase 1 /// growth differentiation factor 1 CERS1 /// GDF1 2657 /// 10715 NM_001290265 /// NM_001492 /// NM_021267 /// NM_198207 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0035690 // cellular response to drug // inferred from direct assay /// 0036146 // cellular response to mycotoxin // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from direct assay /// 0046513 // ceramide biosynthetic process // inferred from sequence or structural similarity /// 0051974 // negative regulation of telomerase activity // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from direct assay /// 0072721 // cellular response to dithiothreitol // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0050291 // sphingosine N-acyltransferase activity // inferred from sequence or structural similarity 206398_s_at NM_001770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001770.1 /DEF=Homo sapiens CD19 antigen (CD19), mRNA. /FEA=mRNA /GEN=CD19 /PROD=CD19 antigen /DB_XREF=gi:10835052 /UG=Hs.96023 CD19 antigen /FL=gb:NM_001770.1 gb:M21097.1 gb:M28170.1 NM_001770 CD19 molecule CD19 930 NM_001178098 /// NM_001770 /// XM_005255696 /// XM_006721103 /// XM_006721104 0006968 // cellular defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206399_x_at NM_023035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023035.1 /DEF=Homo sapiens calcium channel, voltage-dependent, PQ type, alpha 1A subunit (CACNA1A), transcript variant 2, mRNA. /FEA=mRNA /GEN=CACNA1A /PROD=calcium channel, alpha 1A subunit, isoform 2 /DB_XREF=gi:13386497 /UG=Hs.96253 calcium channel, voltage-dependent, PQ type, alpha 1A subunit /FL=gb:NM_023035.1 gb:NM_000068.2 gb:U79666.1 NM_023035 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit /// uncharacterized LOC100507353 CACNA1A /// LOC100507353 773 /// 100507353 NM_000068 /// NM_001127221 /// NM_001127222 /// NM_001174080 /// NM_023035 /// XR_109571 /// XR_133165 /// XR_172267 0000096 // sulfur amino acid metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021590 // cerebellum maturation // inferred from electronic annotation /// 0021679 // cerebellar molecular layer development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032353 // negative regulation of hormone biosynthetic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042133 // neurotransmitter metabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060024 // rhythmic synaptic transmission // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0019905 // syntaxin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206400_at NM_002307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002307.1 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA. /FEA=mRNA /GEN=LGALS7 /PROD=galectin 7 /DB_XREF=gi:4504984 /UG=Hs.99923 lectin, galactoside-binding, soluble, 7 (galectin 7) /FL=gb:L07769.1 gb:NM_002307.1 gb:U06643.1 NM_002307 lectin, galactoside-binding, soluble, 7 /// lectin, galactoside-binding, soluble, 7B LGALS7 /// LGALS7B 3963 /// 653499 NM_001042507 /// NM_002307 0006915 // apoptotic process // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0030246 // carbohydrate binding // inferred from electronic annotation 206401_s_at J03778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03778.1 /DEF=Human microtubule-associated protein tau mRNA, complete cds. /FEA=mRNA /GEN=MTBT1 /DB_XREF=gi:338684 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:BC000558.1 gb:J03778.1 gb:NM_016841.1 J03778 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 206402_s_at NM_003717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003717.1 /DEF=Homo sapiens neuropeptide FF-amide peptide precursor (NPFF), mRNA. /FEA=mRNA /GEN=NPFF /PROD=FMFRamide-related protein precursor /DB_XREF=gi:4503768 /UG=Hs.104555 neuropeptide FF-amide peptide precursor /FL=gb:AF005271.1 gb:NM_003717.1 NM_003717 neuropeptide FF-amide peptide precursor NPFF 8620 NM_003717 /// XM_005269206 0002438 // acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003254 // regulation of membrane depolarization // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0030103 // vasopressin secretion // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070253 // somatostatin secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206403_at NM_014717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014717.1 /DEF=Homo sapiens KIAA0390 gene product (KIAA0390), mRNA. /FEA=mRNA /GEN=KIAA0390 /PROD=KIAA0390 gene product /DB_XREF=gi:7662091 /UG=Hs.108884 KIAA0390 gene product /FL=gb:AB002388.1 gb:NM_014717.1 NM_014717 zinc finger protein 536 ZNF536 9745 NM_014717 /// XM_005259445 /// XM_006723512 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206404_at NM_002010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002010.1 /DEF=Homo sapiens fibroblast growth factor 9 (glia-activating factor) (FGF9), mRNA. /FEA=mRNA /GEN=FGF9 /PROD=fibroblast growth factor 9 (glia-activatingfactor) /DB_XREF=gi:4503706 /UG=Hs.111 fibroblast growth factor 9 (glia-activating factor) /FL=gb:D14838.1 gb:NM_002010.1 NM_002010 fibroblast growth factor 9 FGF9 2254 NM_002010 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 206405_x_at NM_004505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004505.1 /DEF=Homo sapiens ubiquitin specific protease 6 (Tre-2 oncogene) (USP6), mRNA. /FEA=mRNA /GEN=USP6 /PROD=ubiquitin specific protease 6 /DB_XREF=gi:4758563 /UG=Hs.111065 ubiquitin specific protease 6 (Tre-2 oncogene) /FL=gb:NM_004505.1 NM_004505 ubiquitin specific peptidase 32 /// ubiquitin specific peptidase 6 USP32 /// USP6 9098 /// 84669 NM_004505 /// NM_005152 /// NM_032582 /// XM_005256845 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0060627 // regulation of vesicle-mediated transport // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206406_at NM_030663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030663.1 /DEF=Homo sapiens mitochondrial capsule selenoprotein (MCSP), mRNA. /FEA=mRNA /GEN=MCSP /PROD=mitochondrial capsule selenoprotein /DB_XREF=gi:13489057 /UG=Hs.111850 mitochondrial capsule selenoprotein /FL=gb:NM_030663.1 NM_030663 sperm mitochondria-associated cysteine-rich protein SMCP 4184 NM_030663 0007338 // single fertilization // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from sequence or structural similarity /// 0030317 // sperm motility // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 206407_s_at NM_005408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005408.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 13 (SCYA13), mRNA. /FEA=mRNA /GEN=SCYA13 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 13 /DB_XREF=gi:4885586 /UG=Hs.11383 small inducible cytokine subfamily A (Cys-Cys), member 13 /FL=gb:U46767.1 gb:U59808.1 gb:NM_005408.1 NM_005408 chemokine (C-C motif) ligand 13 CCL13 6357 NM_005408 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay 206408_at NM_015564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015564.1 /DEF=Homo sapiens KIAA0416 protein (KIAA0416), mRNA. /FEA=mRNA /GEN=KIAA0416 /PROD=KIAA0416 protein /DB_XREF=gi:7662101 /UG=Hs.114169 KIAA0416 protein /FL=gb:NM_015564.1 NM_015564 leucine rich repeat transmembrane neuronal 2 LRRTM2 26045 NM_015564 0050808 // synapse organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from electronic annotation 206409_at NM_003253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003253.1 /DEF=Homo sapiens T-cell lymphoma invasion and metastasis 1 (TIAM1), mRNA. /FEA=mRNA /GEN=TIAM1 /PROD=T-cell lymphoma invasion and metastasis 1 /DB_XREF=gi:4507500 /UG=Hs.115176 T-cell lymphoma invasion and metastasis 1 /FL=gb:NM_003253.1 gb:U16296.1 NM_003253 T-cell lymphoma invasion and metastasis 1 TIAM1 7074 NM_003253 /// XM_005261037 /// XM_005261038 /// XM_005261039 /// XM_005261040 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0046875 // ephrin receptor binding // inferred from electronic annotation 206410_at NM_021969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021969.1 /DEF=Homo sapiens nuclear receptor subfamily 0, group B, member 2 (NR0B2), mRNA. /FEA=mRNA /GEN=NR0B2 /PROD=short heterodimer partner /DB_XREF=gi:13259502 /UG=Hs.11930 nuclear receptor subfamily 0, group B, member 2 /FL=gb:NM_021969.1 NM_021969 nuclear receptor subfamily 0, group B, member 2 NR0B2 8431 NM_021969 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030521 // androgen receptor signaling pathway // inferred from reviewed computational analysis /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 206411_s_at NM_007314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007314.1 /DEF=Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2), transcript variant b, mRNA. /FEA=mRNA /GEN=ABL2 /PROD=v-abl Abelson murine leukemia viral oncogenehomolog 2 isoform b /DB_XREF=gi:6382061 /UG=Hs.121521 v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) /FL=gb:NM_007314.1 NM_007314 ABL proto-oncogene 2, non-receptor tyrosine kinase ABL2 27 NM_001136000 /// NM_001136001 /// NM_001168236 /// NM_001168237 /// NM_001168238 /// NM_001168239 /// NM_005158 /// NM_007314 /// XM_005245088 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010506 // regulation of autophagy // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030100 // regulation of endocytosis // traceable author statement /// 0030155 // regulation of cell adhesion // traceable author statement /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051353 // positive regulation of oxidoreductase activity // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003785 // actin monomer binding // traceable author statement /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 206412_at NM_005246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005246.1 /DEF=Homo sapiens fer (fpsfes related) tyrosine kinase (phosphoprotein NCP94) (FER), mRNA. /FEA=mRNA /GEN=FER /PROD=fer (fpsfes related) tyrosine kinase(phosphoprotein NCP94) /DB_XREF=gi:4885230 /UG=Hs.121558 fer (fpsfes related) tyrosine kinase (phosphoprotein NCP94) /FL=gb:J03358.1 gb:NM_005246.1 NM_005246 fer (fps/fes related) tyrosine kinase FER 2241 NM_005246 /// XM_005271923 /// XM_006714572 /// XM_006714573 /// XR_427709 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010591 // regulation of lamellipodium assembly // inferred from direct assay /// 0010762 // regulation of fibroblast migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033007 // negative regulation of mast cell activation involved in immune response // inferred from sequence or structural similarity /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from sequence or structural similarity /// 0035426 // extracellular matrix-cell signaling // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // traceable author statement /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from mutant phenotype /// 0036119 // response to platelet-derived growth factor // inferred from sequence or structural similarity /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // inferred from sequence or structural similarity /// 0038109 // Kit signaling pathway // inferred from sequence or structural similarity /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0044331 // cell-cell adhesion mediated by cadherin // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // traceable author statement /// 0050904 // diapedesis // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008157 // protein phosphatase 1 binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0045295 // gamma-catenin binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 206413_s_at NM_004918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004918.1 /DEF=Homo sapiens T-cell leukemialymphoma 1B (TCL1B), mRNA. /FEA=mRNA /GEN=TCL1B /PROD=T-cell leukemialymphoma 1B /DB_XREF=gi:4759219 /UG=Hs.124931 T-cell leukemialymphoma 1B /FL=gb:AF110466.1 gb:NM_004918.1 gb:AF137027.1 NM_004918 T-cell leukemia/lymphoma 1B TCL1B 9623 NM_004918 /// NM_199206 206414_s_at NM_003887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003887.1 /DEF=Homo sapiens development and differentiation enhancing factor 2 (DDEF2), mRNA. /FEA=mRNA /GEN=DDEF2 /PROD=ADP-ribosylation factorarf-directed GTPaseactivating protein /DB_XREF=gi:4502248 /UG=Hs.12802 development and differentiation enhancing factor 2 /FL=gb:AB007860.1 gb:NM_003887.1 NM_003887 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 ASAP2 8853 NM_001135191 /// NM_003887 /// XM_006711898 /// XM_006711899 /// XM_006711900 /// XM_006711901 /// XM_006711902 0001525 // angiogenesis // inferred from electronic annotation /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from electronic annotation /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010764 // negative regulation of fibroblast migration // inferred from electronic annotation /// 0010764 // negative regulation of fibroblast migration // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0016477 // cell migration // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033622 // integrin activation // inferred from electronic annotation /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035148 // tube formation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from direct assay /// 0051451 // myoblast migration // inferred from electronic annotation /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206415_at AI769310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769310 /FEA=EST /DB_XREF=gi:5235819 /DB_XREF=est:wg36d09.x1 /CLONE=IMAGE:2367185 /UG=Hs.129700 tolloid-like 1 /FL=gb:U91963.1 gb:NM_012464.1 gb:AF282732.1 AI769310 tolloid-like 1 TLL1 7092 NM_001204760 /// NM_012464 /// XM_005263192 /// XM_006714293 0001501 // skeletal system development // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206416_at NM_003456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003456.1 /DEF=Homo sapiens zinc finger protein 205 (ZNF205), mRNA. /FEA=mRNA /GEN=ZNF205 /PROD=zinc finger protein 205 /DB_XREF=gi:4508014 /UG=Hs.13128 zinc finger protein 205 /FL=gb:BC002810.1 gb:AF060865.1 gb:NM_003456.1 NM_003456 zinc finger protein 205 ZNF205 7755 NM_001042428 /// NM_001278158 /// NM_003456 /// XM_005255558 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0010729 // positive regulation of hydrogen peroxide biosynthetic process // inferred from mutant phenotype /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206417_at NM_000087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000087.1 /DEF=Homo sapiens cyclic nucleotide gated channel alpha 1 (CNGA1), mRNA. /FEA=mRNA /GEN=CNGA1 /PROD=cyclic nucleotide gated channel alpha 1 /DB_XREF=gi:4502914 /UG=Hs.1323 cyclic nucleotide gated channel alpha 1 /FL=gb:M84741.1 gb:NM_000087.1 NM_000087 cyclic nucleotide gated channel alpha 1 CNGA1 1259 NM_000087 /// NM_001142564 /// XM_005248049 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042391 // regulation of membrane potential // not recorded /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0030553 // cGMP binding // not recorded 206418_at NM_007052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007052.2 /DEF=Homo sapiens NADPH oxidase 1 (NOX1), transcript variant NOH-1L, mRNA. /FEA=mRNA /GEN=NOX1 /PROD=NADPH oxidase 1 isoform long /DB_XREF=gi:6631096 /UG=Hs.132370 NADPH oxidase 1 /FL=gb:AF127763.2 gb:NM_007052.2 NM_007052 NADPH oxidase 1 NOX1 27035 NM_001271815 /// NM_007052 /// NM_013954 /// NM_013955 0001525 // angiogenesis // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred by curator /// 0006746 // FADH2 metabolic process // non-traceable author statement /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006811 // ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009268 // response to pH // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from expression pattern /// 0015992 // proton transport // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042743 // hydrogen peroxide metabolic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from direct assay /// 0072592 // oxygen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred by curator /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030171 // voltage-gated proton channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0050661 // NADP binding // inferred by curator 206419_at NM_005060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005060.1 /DEF=Homo sapiens RAR-related orphan receptor C (RORC), mRNA. /FEA=mRNA /GEN=RORC /PROD=RAR-related orphan receptor C /DB_XREF=gi:4826985 /UG=Hs.133314 RAR-related orphan receptor C /FL=gb:NM_005060.1 gb:U16997.1 NM_005060 RAR-related orphan receptor C RORC 6097 NM_001001523 /// NM_005060 /// XM_005245424 /// XM_006711484 /// XR_426792 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0019218 // regulation of steroid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0036315 // cellular response to sterol // inferred from direct assay /// 0042093 // T-helper cell differentiation // inferred from sequence or structural similarity /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048537 // mucosal-associated lymphoid tissue development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from sequence or structural similarity /// 0060612 // adipose tissue development // inferred from sequence or structural similarity /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from sequence or structural similarity /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0072539 // T-helper 17 cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008142 // oxysterol binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0098531 // direct ligand regulated sequence-specific DNA binding transcription factor activity // inferred from direct assay 206420_at NM_005849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005849.1 /DEF=Homo sapiens immunoglobulin superfamily, member 6 (IGSF6), mRNA. /FEA=mRNA /GEN=IGSF6 /PROD=immunoglobulin superfamily, member 6 /DB_XREF=gi:5031672 /UG=Hs.135194 immunoglobulin superfamily, member 6 /FL=gb:NM_005849.1 NM_005849 immunoglobulin superfamily, member 6 IGSF6 10261 NM_005849 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206421_s_at NM_003784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003784.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7 (SERPINB7), mRNA. /FEA=mRNA /GEN=SERPINB7 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 7 /DB_XREF=gi:4505148 /UG=Hs.138202 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7 /FL=gb:AF027866.1 gb:NM_003784.1 NM_003784 serpin peptidase inhibitor, clade B (ovalbumin), member 7 SERPINB7 8710 NM_001040147 /// NM_001261830 /// NM_001261831 /// NM_003784 /// XM_006722562 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from electronic annotation /// 0090362 // positive regulation of platelet-derived growth factor production // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206422_at NM_002054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002054.1 /DEF=Homo sapiens glucagon (GCG), mRNA. /FEA=mRNA /GEN=GCG /PROD=glucagon /DB_XREF=gi:4503944 /UG=Hs.1460 glucagon /FL=gb:BC005278.1 gb:J04040.1 gb:NM_002054.1 NM_002054 glucagon GCG 2641 NM_002054 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007631 // feeding behavior // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010737 // protein kinase A signaling // not recorded /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // not recorded /// 0042594 // response to starvation // not recorded /// 0043066 // negative regulation of apoptotic process // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0031769 // glucagon receptor binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction 206423_at NM_021146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021146.1 /DEF=Homo sapiens angiopoietin-like factor (CTD6), mRNA. /FEA=mRNA /GEN=CTD6 /PROD=angiopoietin-like factor /DB_XREF=gi:10863948 /UG=Hs.146559 angiopoietin-like factor /FL=gb:NM_021146.1 gb:BC001881.1 NM_021146 angiopoietin-like 7 ANGPTL7 10218 NM_021146 0006979 // response to oxidative stress // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 206424_at NM_000783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000783.1 /DEF=Homo sapiens cytochrome P450, subfamily XXVIA, polypeptide 1 (CYP26A1), mRNA. /FEA=mRNA /GEN=CYP26A1 /PROD=cytochrome P450, subfamily XXVIA, polypeptide 1 /DB_XREF=gi:4503206 /UG=Hs.150595 cytochrome P450, subfamily XXVIA, polypeptide 1 /FL=gb:AF005418.1 gb:NM_000783.1 NM_000783 cytochrome P450, family 26, subfamily A, polypeptide 1 CYP26A1 1592 NM_000783 /// NM_057157 0006766 // vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0034653 // retinoic acid catabolic process // inferred from direct assay /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008401 // retinoic acid 4-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206425_s_at NM_003305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003305.1 /DEF=Homo sapiens transient receptor potential channel 3 (TRPC3), mRNA. /FEA=mRNA /GEN=TRPC3 /PROD=transient receptor potential channel 3 /DB_XREF=gi:4507686 /UG=Hs.150981 transient receptor potential channel 3 /FL=gb:NM_003305.1 NM_003305 transient receptor potential cation channel, subfamily C, member 3 TRPC3 7222 NM_001130698 /// NM_003305 /// XM_006714295 /// XM_006714296 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // traceable author statement /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0033198 // response to ATP // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // traceable author statement /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 206426_at NM_005511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005511.1 /DEF=Homo sapiens melan-A (MLANA), mRNA. /FEA=mRNA /GEN=MLANA /PROD=melan-A /DB_XREF=gi:5031912 /UG=Hs.154069 melan-A /FL=gb:NM_005511.1 gb:U06654.1 NM_005511 melan-A MLANA 2315 NM_005511 /// XM_006716742 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206427_s_at U06654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U06654.1 /DEF=Human differentiation antigen melan-A protein mRNA, complete cds. /FEA=mRNA /PROD=melan-A protein /DB_XREF=gi:517022 /UG=Hs.154069 melan-A /FL=gb:NM_005511.1 gb:U06654.1 U06654 melan-A MLANA 2315 NM_005511 /// XM_006716742 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206428_s_at NM_003442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003442.1 /DEF=Homo sapiens zinc finger protein 143 (clone pHZ-1) (ZNF143), mRNA. /FEA=mRNA /GEN=ZNF143 /PROD=zinc finger protein 143 (clone pHZ-1) /DB_XREF=gi:4507994 /UG=Hs.154095 zinc finger protein 143 (clone pHZ-1) /FL=gb:NM_003442.1 gb:U09850.1 NM_003442 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206429_at NM_005242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005242.2 /DEF=Homo sapiens coagulation factor II (thrombin) receptor-like 1 (F2RL1), mRNA. /FEA=mRNA /GEN=F2RL1 /PROD=coagulation factor II (thrombin) receptor-like 1precursor /DB_XREF=gi:8051581 /UG=Hs.154299 coagulation factor II (thrombin) receptor-like 1 /FL=gb:U34038.1 gb:NM_005242.2 NM_005242 coagulation factor II (thrombin) receptor-like 1 F2RL1 2150 NM_005242 0002286 // T cell activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0002741 // positive regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // inferred from electronic annotation /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from sequence or structural similarity /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0034137 // positive regulation of toll-like receptor 2 signaling pathway // inferred from mutant phenotype /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0034141 // positive regulation of toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035926 // chemokine (C-C motif) ligand 2 secretion // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043311 // positive regulation of eosinophil degranulation // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050702 // interleukin-1 beta secretion // inferred from direct assay /// 0050900 // leukocyte migration // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation /// 0070661 // leukocyte proliferation // inferred from sequence or structural similarity /// 0070963 // positive regulation of neutrophil mediated killing of gram-negative bacterium // inferred from direct assay /// 0072608 // interleukin-10 secretion // inferred from direct assay /// 0072643 // interferon-gamma secretion // inferred from sequence or structural similarity /// 0090195 // chemokine secretion // inferred from direct assay /// 0090198 // negative regulation of chemokine secretion // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from sequence or structural similarity /// 1900135 // positive regulation of renin secretion into blood stream // inferred from sequence or structural similarity /// 2000484 // positive regulation of interleukin-8 secretion // inferred from direct assay /// 2000778 // positive regulation of interleukin-6 secretion // inferred from direct assay 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from sequence or structural similarity 0001965 // G-protein alpha-subunit binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // inferred from electronic annotation /// 0031681 // G-protein beta-subunit binding // inferred from sequence or structural similarity 206430_at NM_001804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001804.1 /DEF=Homo sapiens caudal type homeo box transcription factor 1 (CDX1), mRNA. /FEA=mRNA /GEN=CDX1 /PROD=caudal type homeo box transcription factor 1 /DB_XREF=gi:4502762 /UG=Hs.1545 caudal type homeo box transcription factor 1 /FL=gb:U51095.1 gb:NM_001804.1 gb:AF239666.1 NM_001804 caudal type homeobox 1 CDX1 1044 NM_001804 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060349 // bone morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206431_x_at NM_015043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015043.1 /DEF=Homo sapiens KIAA0676 protein (KIAA0676), mRNA. /FEA=mRNA /GEN=KIAA0676 /PROD=KIAA0676 protein /DB_XREF=gi:13027583 /UG=Hs.155829 KIAA0676 protein /FL=gb:BC000701.1 gb:NM_015043.1 NM_015043 TBC1 domain family, member 9B (with GRAM domain) TBC1D9B 23061 NM_015043 /// NM_198868 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 206432_at NM_005328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005328.1 /DEF=Homo sapiens hyaluronan synthase 2 (HAS2), mRNA. /FEA=mRNA /GEN=HAS2 /PROD=hyaluronan synthase 2 /DB_XREF=gi:4885390 /UG=Hs.159226 hyaluronan synthase 2 /FL=gb:U54804.1 gb:NM_005328.1 NM_005328 hyaluronan synthase 2 HAS2 3037 NM_005328 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030213 // hyaluronan biosynthetic process // inferred from direct assay /// 0030213 // hyaluronan biosynthetic process // inferred from electronic annotation /// 0030213 // hyaluronan biosynthetic process // inferred from mutant phenotype /// 0030213 // hyaluronan biosynthetic process // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0036120 // cellular response to platelet-derived growth factor stimulus // inferred from direct assay /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0070295 // renal water absorption // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071498 // cellular response to fluid shear stress // inferred from expression pattern /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity /// 0090500 // endocardial cushion to mesenchymal transition // inferred from sequence or structural similarity /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0050501 // hyaluronan synthase activity // inferred from mutant phenotype /// 0050501 // hyaluronan synthase activity // inferred from sequence or structural similarity 206433_s_at BC000460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000460.1 /DEF=Homo sapiens, Similar to testican 3, clone MGC:8506, mRNA, complete cds. /FEA=mRNA /PROD=Similar to testican 3 /DB_XREF=gi:12653380 /UG=Hs.159425 testican 3 /FL=gb:BC000460.1 gb:BC003017.1 gb:NM_016950.1 BC000460 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 SPOCK3 50859 NM_001040159 /// NM_001204352 /// NM_001204353 /// NM_001204354 /// NM_001204355 /// NM_001204356 /// NM_001204358 /// NM_001204359 /// NM_001251967 /// NM_016950 /// XM_005263041 0007165 // signal transduction // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206434_at NM_016950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016950.1 /DEF=Homo sapiens testican 3 (HSAJ1454), mRNA. /FEA=mRNA /GEN=HSAJ1454 /PROD=testican 3 /DB_XREF=gi:8393566 /UG=Hs.159425 testican 3 /FL=gb:BC000460.1 gb:BC003017.1 gb:NM_016950.1 NM_016950 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 SPOCK3 50859 NM_001040159 /// NM_001204352 /// NM_001204353 /// NM_001204354 /// NM_001204355 /// NM_001204356 /// NM_001204358 /// NM_001204359 /// NM_001251967 /// NM_016950 /// XM_005263041 0007165 // signal transduction // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206435_at NM_001478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001478.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T) (GALGT), mRNA. /FEA=mRNA /GEN=GALGT /PROD=UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramideN-acetylgalactosaminyltransferase /DB_XREF=gi:4809289 /UG=Hs.159481 UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T) /FL=gb:M83651.1 gb:NM_001478.2 NM_001478 beta-1,4-N-acetyl-galactosaminyl transferase 1 B4GALNT1 2583 NM_001276468 /// NM_001276469 /// NM_001478 /// XM_005268773 /// XM_006719331 0001574 // ganglioside biosynthetic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0030259 // lipid glycosylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003947 // (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0008376 // acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 206436_at NM_001585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001585.1 /DEF=Homo sapiens chromosome 22 open reading frame 1 (C22ORF1), mRNA. /FEA=mRNA /GEN=C22ORF1 /PROD=chromosome 22 open reading frame 1 /DB_XREF=gi:4502496 /UG=Hs.159538 chromosome 22 open reading frame 1 /FL=gb:U84894.1 gb:NM_001585.1 NM_001585 metallophosphoesterase domain containing 1 MPPED1 758 NM_001044370 0008152 // metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 206437_at NM_003775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003775.1 /DEF=Homo sapiens endothelial differentiation, G-protein-coupled receptor 6 (EDG6), mRNA. /FEA=mRNA /GEN=EDG6 /PROD=endothelial differentiation, G protein coupledreceptor 6 precursor /DB_XREF=gi:4503458 /UG=Hs.159543 endothelial differentiation, G-protein-coupled receptor 6 /FL=gb:NM_003775.1 NM_003775 sphingosine-1-phosphate receptor 4 S1PR4 8698 NM_003775 0003376 // sphingosine-1-phosphate signaling pathway // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008289 // lipid binding // traceable author statement /// 0038036 // sphingosine-1-phosphate receptor activity // inferred from electronic annotation 206438_x_at NM_024809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024809.1 /DEF=Homo sapiens hypothetical protein FLJ12975 (FLJ12975), mRNA. /FEA=mRNA /GEN=FLJ12975 /PROD=hypothetical protein FLJ12975 /DB_XREF=gi:13376192 /UG=Hs.167165 hypothetical protein FLJ12975 /FL=gb:NM_024809.1 NM_024809 tectonic family member 2 TCTN2 79867 NM_001143850 /// NM_024809 /// XM_005253623 /// XM_006719605 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206439_at NM_004950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004950.2 /DEF=Homo sapiens dermatan sulphate proteoglycan 3 (DSPG3), mRNA. /FEA=mRNA /GEN=DSPG3 /PROD=dermatan sulphate proteoglycan 3 /DB_XREF=gi:10938018 /UG=Hs.169993 dermatan sulphate proteoglycan 3 /FL=gb:NM_004950.2 gb:U59111.1 NM_004950 epiphycan EPYC 1833 NM_004950 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005539 // glycosaminoglycan binding // traceable author statement 206440_at NM_004664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004664.1 /DEF=Homo sapiens Vertebrate LIN7 homolog 1, Tax interaction protein 33 (VELI1), mRNA. /FEA=mRNA /GEN=VELI1 /PROD=Vertebrate LIN7 homolog 1, Tax interactionprotein 33 /DB_XREF=gi:4759305 /UG=Hs.178215 Vertebrate LIN7 homolog 1, Tax interaction protein 33 /FL=gb:AF087693.1 gb:NM_004664.1 gb:AF173081.1 NM_004664 lin-7 homolog A (C. elegans) LIN7A 8825 NM_004664 /// XM_005269212 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0097016 // L27 domain binding // inferred from physical interaction 206441_s_at NM_017828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017828.1 /DEF=Homo sapiens hypothetical protein FLJ20452 (FLJ20452), mRNA. /FEA=mRNA /GEN=FLJ20452 /PROD=hypothetical protein FLJ20452 /DB_XREF=gi:8923422 /UG=Hs.18490 hypothetical protein FLJ20452 /FL=gb:BC000837.1 gb:NM_017828.1 NM_017828 COMM domain containing 4 COMMD4 54939 NM_001284377 /// NM_001284378 /// NM_001284379 /// NM_017828 /// NR_104312 /// NR_104313 /// XM_005254509 /// XM_005254510 /// XM_005254511 /// XM_005254512 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206442_at NM_003007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003007.1 /DEF=Homo sapiens semenogelin I (SEMG1), mRNA. /FEA=mRNA /GEN=SEMG1 /PROD=semenogelin I /DB_XREF=gi:4506882 /UG=Hs.1968 semenogelin I /FL=gb:J04440.1 gb:NM_003007.1 NM_003007 semenogelin I SEMG1 6406 NM_003007 /// NM_198139 0007320 // insemination // traceable author statement /// 0019953 // sexual reproduction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206443_at NM_006914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006914.1 /DEF=Homo sapiens RAR-related orphan receptor B (RORB), mRNA. /FEA=mRNA /GEN=RORB /PROD=RAR-related orphan receptor B /DB_XREF=gi:5902057 /UG=Hs.198481 RAR-related orphan receptor B /FL=gb:NM_006914.1 NM_006914 RAR-related orphan receptor B RORB 6096 NM_006914 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035881 // amacrine cell differentiation // inferred from sequence or structural similarity /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206444_at NM_000924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000924.1 /DEF=Homo sapiens phosphodiesterase IB, calmodulin-dependent (PDE1B), mRNA. /FEA=mRNA /GEN=PDE1B /PROD=phosphodiesterase IB, calmodulin-dependent /DB_XREF=gi:4505676 /UG=Hs.203238 phosphodiesterase IB, calmodulin-dependent /FL=gb:U56976.1 gb:U86078.1 gb:NM_000924.1 NM_000924 phosphodiesterase 1B, calmodulin-dependent PDE1B 5153 NM_000924 /// NM_001165975 /// NM_001288768 /// NM_001288769 /// XM_006719451 0001505 // regulation of neurotransmitter levels // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030224 // monocyte differentiation // inferred from expression pattern /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from direct assay /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046069 // cGMP catabolic process // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004117 // calmodulin-dependent cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048101 // calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 206445_s_at NM_001536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001536.1 /DEF=Homo sapiens HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 (HRMT1L2), mRNA. /FEA=mRNA /GEN=HRMT1L2 /PROD=HMT1 (hnRNP methyltransferase, S.cerevisiae)-like 2 /DB_XREF=gi:4504496 /UG=Hs.20521 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 /FL=gb:D66904.1 gb:NM_001536.1 NM_001536 protein arginine methyltransferase 1 PRMT1 3276 NM_001207042 /// NM_001536 /// NM_198318 /// NM_198319 /// NR_033397 /// XM_005258842 /// XM_005258844 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006479 // protein methylation // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0018216 // peptidyl-arginine methylation // inferred from direct assay /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // inferred from electronic annotation /// 0035246 // peptidyl-arginine N-methylation // inferred from electronic annotation /// 0035247 // peptidyl-arginine omega-N-methylation // inferred from electronic annotation /// 0043985 // histone H4-R3 methylation // inferred from direct assay /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // not recorded /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // traceable author statement /// 0008170 // N-methyltransferase activity // inferred from direct assay /// 0008170 // N-methyltransferase activity // inferred from mutant phenotype /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // inferred from electronic annotation /// 0016274 // protein-arginine N-methyltransferase activity // inferred from electronic annotation /// 0016275 // [cytochrome c]-arginine N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030519 // snoRNP binding // inferred from electronic annotation /// 0035241 // protein-arginine omega-N monomethyltransferase activity // inferred from electronic annotation /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044020 // histone methyltransferase activity (H4-R3 specific) // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 206446_s_at NM_001971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001971.1 /DEF=Homo sapiens elastase 1, pancreatic (ELA1), mRNA. /FEA=mRNA /GEN=ELA1 /PROD=elastase 1, pancreatic /DB_XREF=gi:4503546 /UG=Hs.21 elastase 1, pancreatic /FL=gb:M16631.1 gb:M16652.1 gb:D00236.1 gb:NM_001971.1 NM_001971 chymotrypsin-like elastase family, member 2A /// chymotrypsin-like elastase family, member 2B CELA2A /// CELA2B 51032 /// 63036 NM_015849 /// NM_033440 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0036457 // keratohyalin granule // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017171 // serine hydrolase activity // inferred from direct assay 206447_at NM_001971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001971.1 /DEF=Homo sapiens elastase 1, pancreatic (ELA1), mRNA. /FEA=mRNA /GEN=ELA1 /PROD=elastase 1, pancreatic /DB_XREF=gi:4503546 /UG=Hs.21 elastase 1, pancreatic /FL=gb:M16631.1 gb:M16652.1 gb:D00236.1 gb:NM_001971.1 NM_001971 chymotrypsin-like elastase family, member 2A /// chymotrypsin-like elastase family, member 2B CELA2A /// CELA2B 51032 /// 63036 NM_015849 /// NM_033440 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0036457 // keratohyalin granule // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017171 // serine hydrolase activity // inferred from direct assay 206448_at NM_014951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014951.1 /DEF=Homo sapiens KIAA0844 protein (KIAA0844), mRNA. /FEA=mRNA /GEN=KIAA0844 /PROD=KIAA0844 protein /DB_XREF=gi:7662331 /UG=Hs.22653 KIAA0844 protein /FL=gb:AB020651.1 gb:NM_014951.1 NM_014951 zinc finger protein 365 ZNF365 22891 NM_014951 /// NM_199450 /// NM_199451 /// NM_199452 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206449_s_at NM_001879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001879.1 /DEF=Homo sapiens mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) (MASP1), mRNA. /FEA=mRNA /GEN=MASP1 /PROD=mannan-binding lectin serine protease 1 /DB_XREF=gi:4505106 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) /FL=gb:NM_001879.1 gb:D28593.1 NM_001879 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) MASP1 5648 NM_001031849 /// NM_001879 /// NM_139125 /// NR_033519 /// XM_006713700 /// XM_006713701 0001867 // complement activation, lectin pathway // inferred from mutant phenotype /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 206450_at NM_000787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000787.1 /DEF=Homo sapiens dopamine beta-hydroxylase (dopamine beta-monooxygenase) (DBH), mRNA. /FEA=mRNA /GEN=DBH /PROD=dopamine beta-hydroxylase (dopaminebeta-monooxygenase) /DB_XREF=gi:4503260 /UG=Hs.2301 dopamine beta-hydroxylase (dopamine beta-monooxygenase) /FL=gb:NM_000787.1 NM_000787 dopamine beta-hydroxylase (dopamine beta-monooxygenase) DBH 1621 NM_000787 0001816 // cytokine production // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002443 // leukocyte mediated immunity // inferred from electronic annotation /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042309 // homoiothermy // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042421 // norepinephrine biosynthetic process // inferred from electronic annotation /// 0042423 // catecholamine biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034466 // chromaffin granule lumen // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement /// 0042583 // chromaffin granule // non-traceable author statement /// 0042584 // chromaffin granule membrane // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004500 // dopamine beta-monooxygenase activity // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206451_at NM_018138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018138.1 /DEF=Homo sapiens hypothetical protein FLJ10560 (FLJ10560), mRNA. /FEA=mRNA /GEN=FLJ10560 /PROD=hypothetical protein FLJ10560 /DB_XREF=gi:8922516 /UG=Hs.235888 hypothetical protein FLJ10560 /FL=gb:NM_018138.1 NM_018138 TBCC domain containing 1 TBCCD1 55171 NM_001134415 /// NM_001286749 /// NM_018138 0000902 // cell morphogenesis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0051661 // maintenance of centrosome location // inferred from mutant phenotype /// 0051684 // maintenance of Golgi location // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 206452_x_at NM_021131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021131.1 /DEF=Homo sapiens protein phosphatase 2A, regulatory subunit B (PR 53) (PPP2R4), mRNA. /FEA=mRNA /GEN=PPP2R4 /PROD=protein phosphatase 2A, regulatory subunit B(PR 53) /DB_XREF=gi:10880986 /UG=Hs.236963 protein phosphatase 2A, regulatory subunit B (PR 53) /FL=gb:NM_021131.1 NM_021131 protein phosphatase 2A activator, regulatory subunit 4 PPP2R4 5524 NM_001193397 /// NM_001271832 /// NM_021131 /// NM_178000 /// NM_178001 /// NM_178002 /// NM_178003 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0030472 // mitotic spindle organization in nucleus // not recorded /// 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008160 // protein tyrosine phosphatase activator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019211 // phosphatase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 206453_s_at NM_016250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016250.1 /DEF=Homo sapiens N-myc downstream-regulated gene 2 (NDRG2), mRNA. /FEA=mRNA /GEN=NDRG2 /PROD=KIAA1248 protein /DB_XREF=gi:10280619 /UG=Hs.243960 N-myc downstream-regulated gene 2 /FL=gb:NM_016250.1 gb:AF159092.3 NM_016250 NDRG family member 2 NDRG2 57447 NM_001282211 /// NM_001282212 /// NM_001282213 /// NM_001282214 /// NM_001282215 /// NM_001282216 /// NM_016250 /// NM_201535 /// NM_201536 /// NM_201537 /// NM_201538 /// NM_201539 /// NM_201540 /// NM_201541 /// XM_005267892 /// XM_005267893 /// XM_005267894 /// XM_005267895 /// XM_005267896 /// XM_005267898 /// XM_005267899 /// XM_005267900 /// XM_005267901 /// XM_005267902 /// XM_005267903 /// XM_005267904 /// XM_005267905 /// XM_005267911 0001818 // negative regulation of cytokine production // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010574 // regulation of vascular endothelial growth factor production // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0090361 // regulation of platelet-derived growth factor production // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206454_s_at AA058836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA058836 /FEA=EST /DB_XREF=gi:1551679 /DB_XREF=est:zf65g12.s1 /CLONE=IMAGE:381862 /UG=Hs.247565 rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant) /FL=gb:NM_000539.2 AA058836 rhodopsin RHO 6010 NM_000539 0001523 // retinoid metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009583 // detection of light stimulus // inferred from electronic annotation /// 0009585 // red, far-red light phototransduction // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071482 // cellular response to light stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from direct assay /// 0060342 // photoreceptor inner segment membrane // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009881 // photoreceptor activity // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206455_s_at NM_000539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000539.2 /DEF=Homo sapiens rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant) (RHO), mRNA. /FEA=mRNA /GEN=RHO /PROD=rhodopsin /DB_XREF=gi:7262389 /UG=Hs.247565 rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant) /FL=gb:NM_000539.2 NM_000539 rhodopsin RHO 6010 NM_000539 0001523 // retinoid metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009583 // detection of light stimulus // inferred from electronic annotation /// 0009585 // red, far-red light phototransduction // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071482 // cellular response to light stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from direct assay /// 0060342 // photoreceptor inner segment membrane // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009881 // photoreceptor activity // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206456_at NM_000810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000810.2 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), mRNA. /FEA=mRNA /GEN=GABRA5 /PROD=gamma-aminobutyric acid (GABA) A receptor, alpha5 precursor /DB_XREF=gi:6031207 /UG=Hs.24969 gamma-aminobutyric acid (GABA) A receptor, alpha 5 /FL=gb:L08485.1 gb:NM_000810.2 NM_000810 gamma-aminobutyric acid (GABA) A receptor, alpha 5 GABRA5 2558 NM_000810 /// NM_001165037 /// XM_005268258 /// XM_006720459 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 206457_s_at NM_000792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000792.2 /DEF=Homo sapiens deiodinase, iodothyronine, type I (DIO1), mRNA. /FEA=mRNA /GEN=DIO1 /PROD=thyroxine deiodinase type 1 /DB_XREF=gi:4557521 /UG=Hs.251415 deiodinase, iodothyronine, type I /FL=gb:NM_000792.2 NM_000792 deiodinase, iodothyronine, type I DIO1 1733 NM_000792 /// NM_001039715 /// NM_001039716 /// NM_213593 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 206458_s_at NM_024494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024494.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 2B (WNT2B), transcript variant WNT-2B2, mRNA. /FEA=mRNA /GEN=WNT2B /PROD=wingless-type MMTV integration site family,member 2B, isoform WNT-2B2 /DB_XREF=gi:13518020 /UG=Hs.258575 wingless-type MMTV integration site family, member 2B /FL=gb:NM_024494.1 gb:AB045117.1 NM_024494 wingless-type MMTV integration site family, member 2B WNT2B 7482 NM_001291880 /// NM_004185 /// NM_024494 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0021871 // forebrain regionalization // inferred from expression pattern /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060492 // lung induction // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation 206459_s_at AB045117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB045117.1 /DEF=Homo sapiens mRNA for WNT-2B Isoform 2, complete cds. /FEA=mRNA /GEN=WNT-2B /PROD=WNT-2B Isoform 2 /DB_XREF=gi:9886741 /UG=Hs.258575 wingless-type MMTV integration site family, member 2B /FL=gb:NM_024494.1 gb:AB045117.1 AB045117 wingless-type MMTV integration site family, member 2B WNT2B 7482 NM_001291880 /// NM_004185 /// NM_024494 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0021871 // forebrain regionalization // inferred from expression pattern /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060492 // lung induction // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation 206460_at NM_018836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018836.1 /DEF=Homo sapiens hypothetical protein (MOT8), mRNA. /FEA=mRNA /GEN=MOT8 /PROD=hypothetical protein /DB_XREF=gi:9055277 /UG=Hs.25924 hypothetical protein /FL=gb:AF175409.1 gb:NM_018836.1 NM_018836 adherens junctions associated protein 1 AJAP1 55966 NM_001042478 /// NM_018836 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 206461_x_at NM_005951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005951.1 /DEF=Homo sapiens metallothionein 1H (MT1H), mRNA. /FEA=mRNA /GEN=MT1H /PROD=metallothionein 1H /DB_XREF=gi:10835084 /UG=Hs.2667 metallothionein 1H /FL=gb:NM_005951.1 NM_005951 metallothionein 1H MT1H 4496 NM_005951 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 206462_s_at NM_002530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002530.1 /DEF=Homo sapiens neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), mRNA. /FEA=mRNA /GEN=NTRK3 /PROD=neurotrophic tyrosine kinase, receptor, type 3 /DB_XREF=gi:4505474 /UG=Hs.26776 neurotrophic tyrosine kinase, receptor, type 3 /FL=gb:U05012.1 gb:NM_002530.1 NM_002530 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 206463_s_at NM_005794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005794.1 /DEF=Homo sapiens short-chain alcohol dehydrogenase family member (HEP27), mRNA. /FEA=mRNA /GEN=HEP27 /PROD=short-chain alcohol dehydrogenase family member /DB_XREF=gi:5031736 /UG=Hs.272499 short-chain alcohol dehydrogenase family member /FL=gb:U31875.1 gb:NM_005794.1 NM_005794 dehydrogenase/reductase (SDR family) member 2 DHRS2 10202 NM_005794 /// NM_182908 /// XM_005267249 /// XM_006720000 /// XM_006720001 /// XM_006720002 /// XR_245654 /// XR_429285 /// XR_429286 0008152 // metabolic process // inferred from electronic annotation /// 0008207 // C21-steroid hormone metabolic process // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from expression pattern /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004090 // carbonyl reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 206464_at NM_001721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001721.1 /DEF=Homo sapiens BMX non-receptor tyrosine kinase (BMX), mRNA. /FEA=mRNA /GEN=BMX /PROD=BMX non-receptor tyrosine kinase /DB_XREF=gi:4502434 /UG=Hs.27372 BMX non-receptor tyrosine kinase /FL=gb:AF045459.1 gb:NM_001721.1 NM_001721 BMX non-receptor tyrosine kinase BMX 660 NM_001721 /// NM_203281 /// XM_006724510 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007498 // mesoderm development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0032587 // ruffle membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206465_at BE856376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856376 /FEA=EST /DB_XREF=gi:10369339 /DB_XREF=est:7f93f09.x1 /CLONE=IMAGE:3304553 /UG=Hs.277543 very long-chain acyl-CoA synthetase; lipidosin /FL=gb:NM_015162.1 gb:AF179481.1 BE856376 acyl-CoA synthetase bubblegum family member 1 ACSBG1 23205 NM_001199377 /// NM_015162 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 206466_at AB014531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014531.1 /DEF=Homo sapiens mRNA for KIAA0631 protein, partial cds. /FEA=mRNA /GEN=KIAA0631 /PROD=KIAA0631 protein /DB_XREF=gi:3327075 /UG=Hs.277543 very long-chain acyl-CoA synthetase; lipidosin /FL=gb:NM_015162.1 gb:AF179481.1 AB014531 acyl-CoA synthetase bubblegum family member 1 ACSBG1 23205 NM_001199377 /// NM_015162 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 206467_x_at NM_003823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003823.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B), mRNA. /FEA=mRNA /GEN=TNFRSF6B /PROD=decoy receptor 3 /DB_XREF=gi:4507584 /UG=Hs.278556 tumor necrosis factor receptor superfamily, member 6b, decoy /FL=gb:AF104419.1 gb:NM_003823.1 gb:AF134240.1 gb:AF217794.1 NM_003823 RTEL1-TNFRSF6B readthrough (NMD candidate) /// tumor necrosis factor receptor superfamily, member 6b, decoy RTEL1-TNFRSF6B /// TNFRSF6B 8771 /// 100533107 NM_003823 /// NM_032945 /// NR_037882 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from sequence or structural similarity /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 206468_s_at NM_015935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015935.1 /DEF=Homo sapiens CGI-01 protein (LOC51603), mRNA. /FEA=mRNA /GEN=LOC51603 /PROD=CGI-01 protein /DB_XREF=gi:7706255 /UG=Hs.278992 CGI-01 protein /FL=gb:AF132936.1 gb:NM_015935.1 NM_015935 methyltransferase like 13 METTL13 51603 NM_001007239 /// NM_014955 /// NM_015935 /// XM_005245256 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206469_x_at NM_012067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012067.1 /DEF=Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) (AKR7A3), mRNA. /FEA=mRNA /GEN=AKR7A3 /PROD=aldo-keto reductase family 7, member A3(aflatoxin aldehyde reductase) /DB_XREF=gi:6912233 /UG=Hs.284236 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) /FL=gb:AF040639.1 gb:NM_012067.1 NM_012067 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) AKR7A3 22977 NM_012067 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0046222 // aflatoxin metabolic process // inferred from electronic annotation /// 0046223 // aflatoxin catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from electronic annotation /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 206470_at NM_005761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005761.1 /DEF=Homo sapiens plexin C1 (PLXNC1), mRNA. /FEA=mRNA /GEN=PLXNC1 /PROD=plexin C1 /DB_XREF=gi:5032222 /UG=Hs.286229 plexin C1 /FL=gb:AF030339.1 gb:NM_005761.1 NM_005761 plexin C1 PLXNC1 10154 NM_005761 /// NR_037687 /// XM_006719186 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206471_s_at NM_005761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005761.1 /DEF=Homo sapiens plexin C1 (PLXNC1), mRNA. /FEA=mRNA /GEN=PLXNC1 /PROD=plexin C1 /DB_XREF=gi:5032222 /UG=Hs.286229 plexin C1 /FL=gb:AF030339.1 gb:NM_005761.1 NM_005761 plexin C1 PLXNC1 10154 NM_005761 /// NR_037687 /// XM_006719186 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206472_s_at NM_005078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005078.1 /DEF=Homo sapiens transducin-like enhancer of split 3, homolog of Drosophila E(sp1) (TLE3), mRNA. /FEA=mRNA /GEN=TLE3 /PROD=transducin-like enhancer of split 3, homolog ofDrosophila E(sp1) /DB_XREF=gi:4827029 /UG=Hs.287362 transducin-like enhancer of split 3, homolog of Drosophila E(sp1) /FL=gb:M99438.1 gb:NM_005078.1 NM_005078 transducin-like enhancer of split 3 TLE3 7090 NM_001105192 /// NM_001282979 /// NM_001282980 /// NM_001282981 /// NM_001282982 /// NM_005078 /// NM_020908 /// XM_005254622 /// XM_005254623 /// XM_005254625 /// XM_005254628 /// XM_005254633 /// XM_006720662 /// XM_006720663 /// XM_006720664 /// XM_006720665 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 206473_at NM_015884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015884.1 /DEF=Homo sapiens S2P protein (S2P), mRNA. /FEA=mRNA /GEN=S2P /PROD=S2P protein /DB_XREF=gi:7706692 /UG=Hs.297007 membrane-bound transcription factor protease, site 2 /FL=gb:AF019612.1 gb:NM_015884.1 NM_015884 membrane-bound transcription factor peptidase, site 2 MBTPS2 51360 NM_015884 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206474_at NM_002595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002595.1 /DEF=Homo sapiens PCTAIRE protein kinase 2 (PCTK2), mRNA. /FEA=mRNA /GEN=PCTK2 /PROD=PCTAIRE protein kinase 2 /DB_XREF=gi:4505648 /UG=Hs.301511 PCTAIRE protein kinase 2 /FL=gb:NM_002595.1 NM_002595 cyclin-dependent kinase 17 CDK17 5128 NM_001170464 /// NM_002595 /// XM_006719444 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206475_x_at NM_022640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022640.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 2, mRNA. /FEA=mRNA /GEN=CSH1 /PROD=chorionic somatomammotropin hormone 1, isoform 2precursor /DB_XREF=gi:12408684 /UG=Hs.324928 chorionic somatomammotropin hormone 1 (placental lactogen) /FL=gb:NM_022640.1 NM_022640 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSHL1 /// GH1 1442 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206476_s_at AI040329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040329 /FEA=EST /DB_XREF=gi:3279523 /DB_XREF=est:oy33b05.x1 /CLONE=IMAGE:1667601 /UG=Hs.33021 neuro-oncological ventral antigen 2 /FL=gb:AF083898.1 gb:NM_002516.1 AI040329 neuro-oncological ventral antigen 2 NOVA2 4858 NM_002516 /// XM_006723229 /// XM_006723230 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 206477_s_at NM_002516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002516.1 /DEF=Homo sapiens neuro-oncological ventral antigen 2 (NOVA2), mRNA. /FEA=mRNA /GEN=NOVA2 /PROD=neuro-oncological ventral antigen 2 /DB_XREF=gi:5902723 /UG=Hs.33021 neuro-oncological ventral antigen 2 /FL=gb:AF083898.1 gb:NM_002516.1 NM_002516 neuro-oncological ventral antigen 2 NOVA2 4858 NM_002516 /// XM_006723229 /// XM_006723230 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 206478_at NM_014792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014792.1 /DEF=Homo sapiens KIAA0125 gene product (KIAA0125), mRNA. /FEA=mRNA /GEN=KIAA0125 /PROD=KIAA0125 gene product /DB_XREF=gi:7661923 /UG=Hs.38365 KIAA0125 gene product /FL=gb:D50915.1 gb:NM_014792.1 NM_014792 KIAA0125 KIAA0125 9834 NM_014151 /// NM_014792 /// NR_026800 206479_at NM_002420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002420.2 /DEF=Homo sapiens melastatin 1 (MLSN1), mRNA. /FEA=mRNA /GEN=MLSN1 /PROD=melastatin 1 /DB_XREF=gi:6006023 /UG=Hs.43265 melastatin 1 /FL=gb:AF071787.1 gb:NM_002420.2 NM_002420 transient receptor potential cation channel, subfamily M, member 1 TRPM1 4308 NM_001252020 /// NM_001252024 /// NM_001252030 /// NM_002420 /// XM_006725544 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007601 // visual perception // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060402 // calcium ion transport into cytosol // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071482 // cellular response to light stimulus // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035841 // new growing cell tip // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay 206480_at NM_000897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000897.1 /DEF=Homo sapiens leukotriene C4 synthase (LTC4S), mRNA. /FEA=mRNA /GEN=LTC4S /PROD=leukotriene C4 synthase /DB_XREF=gi:4505040 /UG=Hs.456 leukotriene C4 synthase /FL=gb:NM_000897.1 gb:U11552.1 gb:U09353.1 NM_000897 leukotriene C4 synthase LTC4S 4056 NM_145867 0003162 // atrioventricular node development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006691 // leukotriene metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from genetic interaction /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // not recorded /// 0019372 // lipoxygenase pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // not recorded /// 0060928 // atrioventricular node cell development // inferred from sequence or structural similarity /// 0060928 // atrioventricular node cell development // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004364 // glutathione transferase activity // not recorded /// 0004464 // leukotriene-C4 synthase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction 206481_s_at NM_001290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001290.1 /DEF=Homo sapiens LIM domain binding 2 (LDB2), mRNA. /FEA=mRNA /GEN=LDB2 /PROD=LIM domain binding 2 /DB_XREF=gi:4504970 /UG=Hs.4980 LIM domain binding 2 /FL=gb:AF047337.1 gb:AF064492.1 gb:AF068651.1 gb:NM_001290.1 NM_001290 LIM domain binding 2 LDB2 9079 NM_001130834 /// NM_001290 /// XM_005248197 /// XM_005248198 /// XM_005248201 /// XM_005248202 /// XM_005248203 /// XM_005248205 /// XM_006713975 /// XM_006713976 /// XM_006713977 /// XM_006713978 /// XM_006713979 /// XM_006713980 /// XM_006713981 /// XM_006713982 /// XM_006713983 /// XM_006713984 0001942 // hair follicle development // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0044089 // positive regulation of cellular component biogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030274 // LIM domain binding // inferred from sequence or structural similarity 206482_at NM_005975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005975.1 /DEF=Homo sapiens PTK6 protein tyrosine kinase 6 (PTK6), mRNA. /FEA=mRNA /GEN=PTK6 /PROD=PTK6 protein tyrosine kinase 6 /DB_XREF=gi:5174646 /UG=Hs.51133 PTK6 protein tyrosine kinase 6 /FL=gb:NM_005975.1 NM_005975 protein tyrosine kinase 6 PTK6 5753 NM_001256358 /// NM_005975 0006468 // protein phosphorylation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042506 // tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0045926 // negative regulation of growth // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0060575 // intestinal epithelial cell differentiation // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 206483_at NM_012472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012472.1 /DEF=Homo sapiens testis specific leucine rich repeat protein (TSLRP), mRNA. /FEA=mRNA /GEN=TSLRP /PROD=testis specific leucine rich repeat protein /DB_XREF=gi:7106436 /UG=Hs.57693 testis specific leucine rich repeat protein /FL=gb:U60666.1 gb:NM_012472.1 NM_012472 leucine rich repeat containing 6 LRRC6 23639 NM_012472 /// NR_073525 /// XM_006716538 /// XM_006716539 /// XR_428377 0000239 // pachytene // inferred from electronic annotation /// 0000239 // pachytene // inferred from sequence or structural similarity /// 0000240 // diplotene // inferred from electronic annotation /// 0000240 // diplotene // inferred from sequence or structural similarity /// 0003341 // cilium movement // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from sequence or structural similarity /// 0030317 // sperm motility // inferred from mutant phenotype /// 0036158 // outer dynein arm assembly // inferred from mutant phenotype /// 0036159 // inner dynein arm assembly // inferred from mutant phenotype /// 0044458 // motile cilium assembly // inferred from mutant phenotype /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from mutant phenotype /// 0061458 // reproductive system development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206484_s_at NM_003399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003399.3 /DEF=Homo sapiens X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (XPNPEP2), mRNA. /FEA=mRNA /GEN=XPNPEP2 /PROD=X-prolyl aminopeptidase 2, membrane-bound /DB_XREF=gi:10880125 /UG=Hs.57922 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound /FL=gb:U90724.2 gb:NM_003399.3 NM_003399 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound XPNPEP2 7512 NM_003399 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206485_at NM_014207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014207.1 /DEF=Homo sapiens CD5 antigen (p56-62) (CD5), mRNA. /FEA=mRNA /GEN=CD5 /PROD=CD5 antigen (p56-62) /DB_XREF=gi:7656964 /UG=Hs.58685 CD5 antigen (p56-62) /FL=gb:NM_014207.1 NM_014207 CD5 molecule CD5 921 NM_014207 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008037 // cell recognition // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206486_at NM_002286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002286.3 /DEF=Homo sapiens lymphocyte-activation gene 3 (LAG3), mRNA. /FEA=mRNA /GEN=LAG3 /PROD=lymphocyte-activation protein 3 precursor /DB_XREF=gi:11693297 /UG=Hs.74011 lymphocyte-activation gene 3 /FL=gb:NM_002286.3 NM_002286 lymphocyte-activation gene 3 LAG3 3902 NM_002286 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0045085 // negative regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042289 // MHC class II protein binding // inferred from direct assay 206487_at NM_025154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025154.1 /DEF=Homo sapiens KIAA0810 protein (KIAA0810), mRNA. /FEA=mRNA /GEN=KIAA0810 /PROD=hypothetical protein FLJ12407 /DB_XREF=gi:13435158 /UG=Hs.7531 KIAA0810 protein /FL=gb:NM_025154.1 NM_025154 Sad1 and UNC84 domain containing 1 SUN1 23353 NM_001130965 /// NM_001171944 /// NM_001171945 /// NM_001171946 /// NM_025154 0006810 // transport // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from genetic interaction /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from mutant phenotype /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation 206488_s_at NM_000072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000072.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor) (CD36), mRNA. /FEA=mRNA /GEN=CD36 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor) /DB_XREF=gi:4557418 /UG=Hs.75613 CD36 antigen (collagen type I receptor, thrombospondin receptor) /FL=gb:M24795.1 gb:M98398.1 gb:L06850.1 gb:NM_000072.1 NM_000072 CD36 molecule (thrombospondin receptor) CD36 948 NM_000072 /// NM_001001547 /// NM_001001548 /// NM_001127443 /// NM_001127444 /// NM_001289908 /// NM_001289909 /// NM_001289911 /// NR_110501 /// XM_005250713 /// XM_005250714 /// XM_005250715 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002221 // pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002576 // platelet degranulation // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010886 // positive regulation of cholesterol storage // inferred from electronic annotation /// 0015911 // plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0019915 // lipid storage // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042953 // lipoprotein transport // inferred from mutant phenotype /// 0042953 // lipoprotein transport // traceable author statement /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0055096 // low-density lipoprotein particle mediated signaling // inferred from electronic annotation /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0071221 // cellular response to bacterial lipopeptide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071447 // cellular response to hydroperoxide // inferred from electronic annotation /// 2000121 // regulation of removal of superoxide radicals // inferred from electronic annotation /// 2000334 // positive regulation of blood microparticle formation // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0045335 // phagocytic vesicle // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from mutant phenotype /// 0005041 // low-density lipoprotein receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0070053 // thrombospondin receptor activity // inferred from sequence or structural similarity /// 0070892 // lipoteichoic acid receptor activity // inferred from electronic annotation /// 0071813 // lipoprotein particle binding // inferred from direct assay 206489_s_at NM_004746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004746.1 /DEF=Homo sapiens discs, large (Drosophila) homolog-associated protein 1 (DLGAP1), mRNA. /FEA=mRNA /GEN=DLGAP1 /PROD=discs, large (Drosophila) homolog-associatedprotein 1 /DB_XREF=gi:4758165 /UG=Hs.75814 discs, large (Drosophila) homolog-associated protein 1 /FL=gb:U67988.1 gb:NM_004746.1 NM_004746 discs, large (Drosophila) homolog-associated protein 1 DLGAP1 9229 NM_001003809 /// NM_001242761 /// NM_001242762 /// NM_001242763 /// NM_001242764 /// NM_001242765 /// NM_001242766 /// NM_004746 /// XM_005258171 /// XM_005258172 /// XM_005258173 /// XM_005258174 /// XM_005258175 /// XM_005258176 /// XM_006722367 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206490_at NM_004746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004746.1 /DEF=Homo sapiens discs, large (Drosophila) homolog-associated protein 1 (DLGAP1), mRNA. /FEA=mRNA /GEN=DLGAP1 /PROD=discs, large (Drosophila) homolog-associatedprotein 1 /DB_XREF=gi:4758165 /UG=Hs.75814 discs, large (Drosophila) homolog-associated protein 1 /FL=gb:U67988.1 gb:NM_004746.1 NM_004746 discs, large (Drosophila) homolog-associated protein 1 DLGAP1 9229 NM_001003809 /// NM_001242761 /// NM_001242762 /// NM_001242763 /// NM_001242764 /// NM_001242765 /// NM_001242766 /// NM_004746 /// XM_005258171 /// XM_005258172 /// XM_005258173 /// XM_005258174 /// XM_005258175 /// XM_005258176 /// XM_006722367 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206491_s_at NM_003827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003827.1 /DEF=Homo sapiens N-ethylmaleimide-sensitive factor attachment protein, alpha (NAPA), mRNA. /FEA=mRNA /GEN=NAPA /PROD=N-ethylmaleimide-sensitive factor attachmentprotein, alpha /DB_XREF=gi:4505328 /UG=Hs.75932 N-ethylmaleimide-sensitive factor attachment protein, alpha /FL=gb:U39412.1 gb:NM_003827.1 NM_003827 N-ethylmaleimide-sensitive factor attachment protein, alpha NAPA 8775 NM_003827 /// NR_038456 /// NR_038457 /// XM_006723454 /// XM_006723455 /// XM_006723456 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0010807 // regulation of synaptic vesicle priming // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035494 // SNARE complex disassembly // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 206492_at NM_002012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002012.1 /DEF=Homo sapiens fragile histidine triad gene (FHIT), mRNA. /FEA=mRNA /GEN=FHIT /PROD=fragile histidine triad gene /DB_XREF=gi:4503718 /UG=Hs.77252 fragile histidine triad gene /FL=gb:U46922.1 gb:NM_002012.1 NM_002012 fragile histidine triad FHIT 2272 NM_001166243 /// NM_002012 /// XM_005264951 /// XM_005264952 /// XM_005264953 /// XM_006713027 0006163 // purine nucleotide metabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // traceable author statement /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0047710 // bis(5'-adenosyl)-triphosphatase activity // inferred from direct assay 206493_at NM_000419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000419.2 /DEF=Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) (ITGA2B), mRNA. /FEA=mRNA /GEN=ITGA2B /PROD=integrin alpha 2b precursor /DB_XREF=gi:6006009 /UG=Hs.785 integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) /FL=gb:M34480.1 gb:J02764.1 gb:NM_000419.2 NM_000419 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ITGA2B 3674 NM_000419 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0070527 // platelet aggregation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 206494_s_at NM_000419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000419.2 /DEF=Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) (ITGA2B), mRNA. /FEA=mRNA /GEN=ITGA2B /PROD=integrin alpha 2b precursor /DB_XREF=gi:6006009 /UG=Hs.785 integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) /FL=gb:M34480.1 gb:J02764.1 gb:NM_000419.2 NM_000419 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ITGA2B 3674 NM_000419 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0070527 // platelet aggregation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 206495_s_at NM_015517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015517.1 /DEF=Homo sapiens DKFZP434F162 protein (DKFZP434F162), mRNA. /FEA=mRNA /GEN=DKFZP434F162 /PROD=DKFZP434F162 protein /DB_XREF=gi:13027589 /UG=Hs.7987 DKFZP434F162 protein /FL=gb:BC001073.1 gb:BC001945.1 gb:NM_015517.1 NM_015517 histone H4 transcription factor HINFP 25988 NM_001243259 /// NM_015517 /// NM_198971 /// XM_006718813 /// XM_006718814 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045445 // myoblast differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206496_at NM_006894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006894.2 /DEF=Homo sapiens flavin containing monooxygenase 3 (FMO3), mRNA. /FEA=mRNA /GEN=FMO3 /PROD=flavin containing monooxygenase 3 /DB_XREF=gi:6325466 /UG=Hs.80876 flavin containing monooxygenase 3 /FL=gb:M83772.1 gb:NM_006894.2 NM_006894 flavin containing monooxygenase 3 FMO3 2328 NM_001002294 /// NM_006894 /// XM_005245044 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0034899 // trimethylamine monooxygenase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 206497_at NM_018224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018224.1 /DEF=Homo sapiens hypothetical protein FLJ10803 (FLJ10803), mRNA. /FEA=mRNA /GEN=FLJ10803 /PROD=hypothetical protein FLJ10803 /DB_XREF=gi:8922676 /UG=Hs.8173 hypothetical protein FLJ10803 /FL=gb:NM_018224.1 NM_018224 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) COA1 55744 NM_018224 /// NR_047701 /// XM_005249804 /// XM_005249806 /// XM_005249807 /// XM_006715751 /// XM_006715752 /// XR_242093 /// XR_242094 /// XR_242095 /// XR_428082 /// XR_428083 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0033617 // mitochondrial respiratory chain complex IV assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 206498_at NM_000275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000275.1 /DEF=Homo sapiens oculocutaneous albinism II (pink-eye dilution (murine) homolog) (OCA2), mRNA. /FEA=mRNA /GEN=OCA2 /PROD=P protein /DB_XREF=gi:4557810 /UG=Hs.82027 oculocutaneous albinism II (pink-eye dilution (murine) homolog) /FL=gb:M99564.1 gb:NM_000275.1 NM_000275 oculocutaneous albinism II OCA2 4948 NM_000275 /// XM_005268259 0006726 // eye pigment biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015700 // arsenite transport // inferred from electronic annotation /// 0015828 // tyrosine transport // traceable author statement /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005302 // L-tyrosine transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015105 // arsenite transmembrane transporter activity // inferred from electronic annotation 206499_s_at NM_001269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001269.1 /DEF=Homo sapiens chromosome condensation 1 (CHC1), mRNA. /FEA=mRNA /GEN=CHC1 /PROD=chromosome condensation 1 /DB_XREF=gi:4502800 /UG=Hs.84746 chromosome condensation 1 /FL=gb:NM_001269.1 NM_001269 regulator of chromosome condensation 1 RCC1 1104 NM_001048194 /// NM_001048195 /// NM_001048199 /// NM_001269 /// NR_030725 /// NR_030726 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032316 // regulation of Ran GTPase activity // inferred from direct assay /// 0032316 // regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from direct assay /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay 206500_s_at NM_018353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018353.1 /DEF=Homo sapiens hypothetical protein FLJ11186 (FLJ11186), mRNA. /FEA=mRNA /GEN=FLJ11186 /PROD=hypothetical protein FLJ11186 /DB_XREF=gi:8922924 /UG=Hs.89278 hypothetical protein FLJ11186 /FL=gb:NM_018353.1 NM_018353 MIS18 binding protein 1 MIS18BP1 55320 NM_018353 /// XM_005267833 0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206501_x_at NM_004956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004956.1 /DEF=Homo sapiens ets variant gene 1 (ETV1), mRNA. /FEA=mRNA /GEN=ETV1 /PROD=ets variant gene 1 /DB_XREF=gi:4826717 /UG=Hs.89566 ets variant gene 1 /FL=gb:NM_004956.1 gb:U17163.1 NM_004956 ets variant 1 ETV1 2115 NM_001163147 /// NM_001163148 /// NM_001163149 /// NM_001163150 /// NM_001163151 /// NM_001163152 /// NM_004956 /// NR_120445 /// XM_005249635 /// XM_005249636 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // traceable author statement 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206502_s_at NM_002196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002196.1 /DEF=Homo sapiens insulinoma-associated 1 (INSM1), mRNA. /FEA=mRNA /GEN=INSM1 /PROD=insulinoma-associated 1 /DB_XREF=gi:4504712 /UG=Hs.89584 insulinoma-associated 1 /FL=gb:M93119.1 gb:NM_002196.1 NM_002196 insulinoma-associated 1 INSM1 3642 NM_002196 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0003309 // type B pancreatic cell differentiation // inferred from sequence or structural similarity /// 0003310 // pancreatic A cell differentiation // inferred from sequence or structural similarity /// 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035270 // endocrine system development // inferred from electronic annotation /// 0042421 // norepinephrine biosynthetic process // inferred from sequence or structural similarity /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from direct assay /// 0061104 // adrenal chromaffin cell differentiation // inferred from sequence or structural similarity /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0030332 // cyclin binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206503_x_at NM_002675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002675.1 /DEF=Homo sapiens promyelocytic leukemia (PML), mRNA. /FEA=mRNA /GEN=PML /PROD=promyelocytic leukemia /DB_XREF=gi:4505902 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230406.1 gb:M73778.1 gb:NM_002675.1 NM_002675 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 206504_at NM_000782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000782.1 /DEF=Homo sapiens cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) (CYP24), mRNA. /FEA=mRNA /GEN=CYP24 /PROD=cytochrome P450, subfamily XXIV (vitamin D24-hydroxylase) /DB_XREF=gi:4503204 /UG=Hs.89663 cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) /FL=gb:L13286.1 gb:NM_000782.1 NM_000782 cytochrome P450, family 24, subfamily A, polypeptide 1 CYP24A1 1591 NM_000782 /// NM_001128915 /// XM_005260304 0001649 // osteoblast differentiation // inferred from expression pattern /// 0006766 // vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0033280 // response to vitamin D // inferred from direct assay /// 0042359 // vitamin D metabolic process // traceable author statement /// 0042369 // vitamin D catabolic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070561 // vitamin D receptor signaling pathway // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008403 // 25-hydroxycholecalciferol-24-hydroxylase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // traceable author statement /// 0030342 // 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206505_at NM_021139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021139.1 /DEF=Homo sapiens UDP glycosyltransferase 2 family, polypeptide B4 (UGT2B4), mRNA. /FEA=mRNA /GEN=UGT2B4 /PROD=UDP glycosyltransferase 2 family, polypeptideB4 /DB_XREF=gi:10863940 /UG=Hs.89691 UDP glycosyltransferase 2 family, polypeptide B4 /FL=gb:NM_021139.1 gb:AF064200.1 gb:AF081793.1 NM_021139 UDP glucuronosyltransferase 2 family, polypeptide B4 UGT2B4 7363 NM_021139 /// XM_005265700 /// XM_005265701 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006711 // estrogen catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from direct assay /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0052695 // cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 206506_s_at NM_003599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003599.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 3 homolog (SUPT3H), mRNA. /FEA=mRNA /GEN=SUPT3H /PROD=suppressor of Ty (S.cerevisiae) 3 homolog /DB_XREF=gi:4507308 /UG=Hs.96757 suppressor of Ty (S.cerevisiae) 3 homolog /FL=gb:AF073930.1 gb:AF069734.1 gb:NM_003599.1 NM_003599 suppressor of Ty 3 homolog (S. cerevisiae) SUPT3H 8464 NM_001261823 /// NM_003599 /// NM_181356 /// XM_005249450 /// XM_005249451 /// XM_006715230 /// XR_427837 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206507_at NM_014724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014724.1 /DEF=Homo sapiens KIAA0426 gene product (KIAA0426), mRNA. /FEA=mRNA /GEN=KIAA0426 /PROD=KIAA0426 gene product /DB_XREF=gi:7662109 /UG=Hs.97476 KIAA0426 gene product /FL=gb:AB007886.1 gb:NM_014724.1 NM_014724 zinc finger and SCAN domain containing 12 ZSCAN12 9753 NM_001039643 /// NM_001163391 /// NM_014724 /// NR_028077 /// XM_006715282 /// XM_006715283 /// XM_006715284 /// XR_427859 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206508_at NM_001252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001252.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7), mRNA. /FEA=mRNA /GEN=TNFSF7 /PROD=CD70 antigen (CD27 ligand) /DB_XREF=gi:4507604 /UG=Hs.99899 tumor necrosis factor (ligand) superfamily, member 7 /FL=gb:BC000725.1 gb:L08096.1 gb:NM_001252.1 NM_001252 CD70 molecule CD70 970 NM_001252 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206509_at NM_002652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002652.1 /DEF=Homo sapiens prolactin-induced protein (PIP), mRNA. /FEA=mRNA /GEN=PIP /PROD=prolactin-induced protein /DB_XREF=gi:4505820 /UG=Hs.99949 prolactin-induced protein /FL=gb:J03460.1 gb:NM_002652.1 NM_002652 prolactin-induced protein PIP 5304 NM_002652 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0006508 // proteolysis // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003779 // actin binding // non-traceable author statement /// 0004190 // aspartic-type endopeptidase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 206510_at AF332197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332197.1 /DEF=Homo sapiens adult SIX2 (SIX2) mRNA, complete cds. /FEA=mRNA /GEN=SIX2 /PROD=SIX2 /DB_XREF=gi:13242164 /UG=Hs.101937 sine oculis homeobox (Drosophila) homolog 2 /FL=gb:AF332197.1 gb:AF136940.1 gb:NM_016932.1 AF332197 SIX homeobox 2 SIX2 10736 NM_016932 /// XM_005264100 0001656 // metanephros development // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007501 // mesodermal cell fate specification // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206511_s_at NM_016932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016932.1 /DEF=Homo sapiens sine oculis homeobox (Drosophila) homolog 2 (SIX2), mRNA. /FEA=mRNA /GEN=SIX2 /PROD=sine oculis homeobox (Drosophila) homolog 2 /DB_XREF=gi:8394273 /UG=Hs.101937 sine oculis homeobox (Drosophila) homolog 2 /FL=gb:AF332197.1 gb:AF136940.1 gb:NM_016932.1 NM_016932 SIX homeobox 2 SIX2 10736 NM_016932 /// XM_005264100 0001656 // metanephros development // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007501 // mesodermal cell fate specification // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206512_at NM_005083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005083.2 /DEF=Homo sapiens U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 1 (U2AF1RS1), mRNA. /FEA=mRNA /GEN=U2AF1RS1 /PROD=U2 small nuclear ribonucleoprotein auxiliaryfactor, small subunit-related protein 1 /DB_XREF=gi:13186299 /UG=Hs.103962 U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 1 /FL=gb:D49676.1 gb:NM_005083.2 NM_005083 signal recognition particle 19kDa /// zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 SRP19 /// ZRSR1 6728 /// 7310 NM_001204193 /// NM_001204194 /// NM_001204196 /// NM_001204199 /// NM_003135 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206513_at NM_004833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004833.1 /DEF=Homo sapiens absent in melanoma 2 (AIM2), mRNA. /FEA=mRNA /GEN=AIM2 /PROD=absent in melanoma 2 /DB_XREF=gi:4757733 /UG=Hs.105115 absent in melanoma 2 /FL=gb:AF024714.1 gb:NM_004833.1 NM_004833 absent in melanoma 2 AIM2 9447 NM_004833 /// XM_005245616 /// XM_005245617 /// XM_006711633 /// XR_241107 /// XR_241108 0002218 // activation of innate immune response // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032731 // positive regulation of interleukin-1 beta production // inferred from direct assay /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070269 // pyroptosis // inferred from direct assay /// 2001056 // positive regulation of cysteine-type endopeptidase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 206514_s_at D12620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D12620.1 /DEF=Homo sapiens mRNA for cytochrome P-450LTBV, complete cds. /FEA=mRNA /PROD=cytochrome P-450LTBV /DB_XREF=gi:391715 /UG=Hs.106242 cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase) /FL=gb:AB002454.1 gb:D12620.1 gb:NM_000896.1 D12620 cytochrome P450, family 4, subfamily F, polypeptide 2 /// cytochrome P450, family 4, subfamily F, polypeptide 3 CYP4F2 /// CYP4F3 4051 /// 8529 NM_000896 /// NM_001082 /// NM_001199208 /// NM_001199209 /// XM_005259911 /// XM_006722751 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0003091 // renal water homeostasis // inferred from expression pattern /// 0003095 // pressure natriuresis // inferred from expression pattern /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from mutant phenotype /// 0032304 // negative regulation of icosanoid secretion // inferred from mutant phenotype /// 0032305 // positive regulation of icosanoid secretion // inferred from mutant phenotype /// 0036101 // leukotriene B4 catabolic process // inferred from electronic annotation /// 0036101 // leukotriene B4 catabolic process // inferred from direct assay /// 0042360 // vitamin E metabolic process // inferred from direct assay /// 0042371 // vitamin K biosynthetic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047057 // vitamin-K-epoxide reductase (warfarin-sensitive) activity // inferred from mutant phenotype /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from electronic annotation /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from direct assay /// 0052869 // arachidonic acid omega-hydroxylase activity // inferred from direct assay /// 0052870 // tocopherol omega-hydroxylase activity // inferred from electronic annotation /// 0052871 // alpha-tocopherol omega-hydroxylase activity // inferred from electronic annotation /// 0052871 // alpha-tocopherol omega-hydroxylase activity // inferred from direct assay /// 0052872 // tocotrienol omega-hydroxylase activity // inferred from direct assay 206515_at NM_000896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000896.1 /DEF=Homo sapiens cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase) (CYP4F3), mRNA. /FEA=mRNA /GEN=CYP4F3 /PROD=cytochrome P450, subfamily IVF, polypeptide 3 /DB_XREF=gi:4503240 /UG=Hs.106242 cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase) /FL=gb:AB002454.1 gb:D12620.1 gb:NM_000896.1 NM_000896 cytochrome P450, family 4, subfamily F, polypeptide 3 CYP4F3 4051 NM_000896 /// NM_001199208 /// NM_001199209 /// XM_005259911 /// XM_006722751 0006690 // icosanoid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0036101 // leukotriene B4 catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from electronic annotation /// 0052870 // tocopherol omega-hydroxylase activity // inferred from electronic annotation /// 0052871 // alpha-tocopherol omega-hydroxylase activity // inferred from electronic annotation 206516_at NM_000479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000479.2 /DEF=Homo sapiens anti-Mullerian hormone (AMH), mRNA. /FEA=mRNA /GEN=AMH /PROD=anti-Mullerian hormone /DB_XREF=gi:6138973 /UG=Hs.112432 anti-Mullerian hormone /FL=gb:NM_000479.2 NM_000479 anti-Mullerian hormone /// microRNA 4321 AMH /// MIR4321 268 /// 100423031 NM_000479 /// NR_036207 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001546 // preantral ovarian follicle growth // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from direct assay /// 0001880 // Mullerian duct regression // non-traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007506 // gonadal mesoderm development // inferred from electronic annotation /// 0007530 // sex determination // traceable author statement /// 0007548 // sex differentiation // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008406 // gonad development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206517_at NM_004062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004062.1 /DEF=Homo sapiens cadherin 16, KSP-cadherin (CDH16), mRNA. /FEA=mRNA /GEN=CDH16 /PROD=cadherin 16, KSP-cadherin /DB_XREF=gi:4757955 /UG=Hs.115418 cadherin 16, KSP-cadherin /FL=gb:AF016272.1 gb:NM_004062.1 NM_004062 cadherin 16, KSP-cadherin CDH16 1014 NM_001204744 /// NM_001204745 /// NM_001204746 /// NM_004062 /// XM_005255768 /// XM_005255769 /// XM_005255770 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206518_s_at NM_003835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003835.1 /DEF=Homo sapiens regulator of G-protein signalling 9 (RGS9), mRNA. /FEA=mRNA /GEN=RGS9 /PROD=regulator of G-protein signalling 9 /DB_XREF=gi:4506520 /UG=Hs.117149 regulator of G-protein signalling 9 /FL=gb:AF073710.1 gb:NM_003835.1 NM_003835 regulator of G-protein signaling 9 RGS9 8787 NM_001081955 /// NM_001165933 /// NM_003835 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 206519_x_at D86358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86358.1 /DEF=Homo sapiens mRNA for CD33L1, complete cds. /FEA=mRNA /PROD=CD33L1 /DB_XREF=gi:2913994 /UG=Hs.117992 sialic acid binding Ig-like lectin 6 /FL=gb:U71382.1 gb:D86358.1 gb:NM_001245.1 D86358 sialic acid binding Ig-like lectin 6 SIGLEC6 946 NM_001177547 /// NM_001177548 /// NM_001177549 /// NM_001245 /// NM_198845 /// NM_198846 /// XR_243971 /// XR_243972 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 206520_x_at NM_001245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001245.1 /DEF=Homo sapiens sialic acid binding Ig-like lectin 6 (SIGLEC6), mRNA. /FEA=mRNA /GEN=SIGLEC6 /PROD=sialic acid binding Ig-like lectin 6 /DB_XREF=gi:4502656 /UG=Hs.117992 sialic acid binding Ig-like lectin 6 /FL=gb:U71382.1 gb:D86358.1 gb:NM_001245.1 NM_001245 sialic acid binding Ig-like lectin 6 SIGLEC6 946 NM_001177547 /// NM_001177548 /// NM_001177549 /// NM_001245 /// NM_198845 /// NM_198846 /// XR_243971 /// XR_243972 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 206521_s_at NM_015859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015859.1 /DEF=Homo sapiens general transcription factor IIA, 1 (37kD and 19kD subunits) (GTF2A1), mRNA. /FEA=mRNA /GEN=GTF2A1 /PROD=TFIIA alpha, p55 /DB_XREF=gi:7706734 /UG=Hs.121686 general transcription factor IIA, 1 (37kD and 19kD subunits) /FL=gb:D14887.1 gb:NM_015859.1 NM_015859 general transcription factor IIA, 1, 19/37kDa GTF2A1 2957 NM_001278940 /// NM_015859 /// NM_201595 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005672 // transcription factor TFIIA complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 206522_at NM_004668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004668.1 /DEF=Homo sapiens maltase-glucoamylase (alpha-glucosidase) (MGAM), mRNA. /FEA=mRNA /GEN=MGAM /PROD=alpha-glucosidase /DB_XREF=gi:4758711 /UG=Hs.122785 maltase-glucoamylase (alpha-glucosidase) /FL=gb:AF016833.1 gb:NM_004668.1 NM_004668 maltase-glucoamylase (alpha-glucosidase) MGAM 8972 NM_004668 /// XM_006716168 /// XM_006716169 0005975 // carbohydrate metabolic process // traceable author statement /// 0005983 // starch catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044245 // polysaccharide digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004339 // glucan 1,4-alpha-glucosidase activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004558 // alpha-glucosidase activity // traceable author statement /// 0016160 // amylase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032450 // maltose alpha-glucosidase activity // inferred from electronic annotation 206523_at NM_004227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004227.2 /DEF=Homo sapiens pleckstrin homology, Sec7 and coiledcoil domains 3 (PSCD3), mRNA. /FEA=mRNA /GEN=PSCD3 /PROD=pleckstrin homology, Sec7 and coiledcoildomains 3 /DB_XREF=gi:8670548 /UG=Hs.129811 pleckstrin homology, Sec7 and coiledcoil domains 3 /FL=gb:AJ005197.1 gb:NM_004227.2 NM_004227 cytohesin 3 CYTH3 9265 NM_004227 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 206524_at NM_003181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003181.1 /DEF=Homo sapiens T brachyury (mouse) homolog (T), mRNA. /FEA=mRNA /GEN=T /PROD=T brachyury (mouse) homolog /DB_XREF=gi:4507338 /UG=Hs.143507 T brachyury (mouse) homolog /FL=gb:NM_003181.1 NM_003181 T, brachyury homolog (mouse) T 6862 NM_001270484 /// NM_003181 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001839 // neural plate morphogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from direct assay /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0007509 // mesoderm migration involved in gastrulation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008595 // anterior/posterior axis specification, embryo // traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0014028 // notochord formation // inferred from electronic annotation /// 0022414 // reproductive process // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 0090009 // primitive streak formation // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206525_at NM_002042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002042.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) receptor, rho 1 (GABRR1), mRNA. /FEA=mRNA /GEN=GABRR1 /PROD=gamma-aminobutyric acid (GABA) receptor, rho 1precursor /DB_XREF=gi:4503868 /UG=Hs.1438 gamma-aminobutyric acid (GABA) receptor, rho 1 /FL=gb:M62400.1 gb:NM_002042.1 NM_002042 gamma-aminobutyric acid (GABA) A receptor, rho 1 GABRR1 2569 NM_001256703 /// NM_001256704 /// NM_001267582 /// NM_002042 /// XM_006715438 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 206526_at NM_015653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015653.1 /DEF=Homo sapiens DKFZP566F0546 protein (DKFZP566F0546), mRNA. /FEA=mRNA /GEN=DKFZP566F0546 /PROD=hypothetical protein MGC4107 /DB_XREF=gi:13124762 /UG=Hs.144505 DKFZP566F0546 protein /FL=gb:BC003024.1 gb:NM_015653.1 NM_015653 RIB43A domain with coiled-coils 2 RIBC2 26150 NM_015653 /// XM_005261524 0005634 // nucleus // inferred from direct assay 206527_at NM_000663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000663.1 /DEF=Homo sapiens 4-aminobutyrate aminotransferase (ABAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ABAT /PROD=4-aminobutyrate aminotransferase precursor /DB_XREF=gi:4501846 /UG=Hs.1588 4-aminobutyrate aminotransferase /FL=gb:NM_000663.1 gb:L32961.1 NM_000663 4-aminobutyrate aminotransferase ABAT 18 NM_000663 /// NM_001127448 /// NM_020686 /// XM_005255154 0001666 // response to hypoxia // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007620 // copulation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // non-traceable author statement /// 0010039 // response to iron ion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // non-traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0032144 // 4-aminobutyrate transaminase complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003867 // 4-aminobutyrate transaminase activity // inferred from direct assay /// 0003867 // 4-aminobutyrate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0032145 // succinate-semialdehyde dehydrogenase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047298 // (S)-3-amino-2-methylpropionate transaminase activity // inferred from electronic annotation 206528_at NM_004621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004621.2 /DEF=Homo sapiens transient receptor potential channel 6 (TRPC6), mRNA. /FEA=mRNA /GEN=TRPC6 /PROD=transient receptor potential channel 6 /DB_XREF=gi:5730101 /UG=Hs.159003 transient receptor potential channel 6 /FL=gb:AF080394.2 gb:NM_004621.2 NM_004621 transient receptor potential cation channel, subfamily C, member 6 TRPC6 7225 NM_004621 /// XM_006718898 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032414 // positive regulation of ion transmembrane transporter activity // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 206529_x_at NM_000441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000441.1 /DEF=Homo sapiens Pendred syndrome (SLC26A4), mRNA. /FEA=mRNA /GEN=SLC26A4 /PROD=pendrin /DB_XREF=gi:4505696 /UG=Hs.159275 solute carrier family, member 4 /FL=gb:AF030880.1 gb:NM_000441.1 NM_000441 solute carrier family 26 (anion exchanger), member 4 SLC26A4 5172 NM_000441 /// XM_005250425 /// XM_005250426 /// XM_006716024 /// XM_006716025 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // traceable author statement /// 0008272 // sulfate transport // traceable author statement /// 0015698 // inorganic anion transport // traceable author statement /// 0015705 // iodide transport // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015108 // chloride transmembrane transporter activity // inferred from electronic annotation /// 0015111 // iodide transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // traceable author statement 206530_at NM_014488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014488.1 /DEF=Homo sapiens RAB30, member RAS oncogene family (RAB30), mRNA. /FEA=mRNA /GEN=RAB30 /PROD=RAB30, member RAS oncogene family /DB_XREF=gi:7657493 /UG=Hs.159505 RAB30, member RAS oncogene family /FL=gb:NM_014488.1 NM_014488 RAB30, member RAS oncogene family RAB30 27314 NM_001286059 /// NM_001286060 /// NM_001286061 /// NM_014488 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // traceable author statement /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 206531_at NM_004647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004647.1 /DEF=Homo sapiens Neuro-d4 (rat) homolog (NEUD4), mRNA. /FEA=mRNA /GEN=NEUD4 /PROD=Neuro-d4 (rat) homolog /DB_XREF=gi:4758797 /UG=Hs.159589 Neuro-d4 (rat) homolog /FL=gb:U43843.1 gb:NM_004647.1 NM_004647 D4, zinc and double PHD fingers family 1 DPF1 8193 NM_001135155 /// NM_001135156 /// NM_001289978 /// NM_004647 /// XM_005259288 /// XM_005259289 /// XM_005259290 /// XM_005259292 /// XM_006723407 /// XM_006723408 /// XM_006723409 /// XM_006723410 /// XR_243964 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007399 // nervous system development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206532_at NM_003073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003073.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1), mRNA. /FEA=mRNA /GEN=SMARCB1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily b, member 1 /DB_XREF=gi:4507076 /UG=Hs.159971 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 /FL=gb:U04847.1 gb:NM_003073.1 NM_003073 0001824 // blastocyst development // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0006281 // DNA repair // /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0015074 // DNA integration // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // /// 0030154 // cell differentiation // inferred from electronic annotation /// 0039692 // single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0044772 // mitotic cell cycle phase transition // /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from electronic annotation /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from electronic annotation /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 206533_at NM_000745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000745.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 5 (CHRNA5), mRNA. /FEA=mRNA /GEN=CHRNA5 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 5 /DB_XREF=gi:4502828 /UG=Hs.1614 cholinergic receptor, nicotinic, alpha polypeptide 5 /FL=gb:U62434.1 gb:M83712.1 gb:NM_000745.1 NM_000745 cholinergic receptor, nicotinic, alpha 5 (neuronal) CHRNA5 1138 NM_000745 /// XM_005254142 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // non-traceable author statement /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay 206534_at NM_000833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000833.2 /DEF=Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A), mRNA. /FEA=mRNA /GEN=GRIN2A /PROD=N-methyl-D-aspartate receptor subunit 2Aprecursor /DB_XREF=gi:6006002 /UG=Hs.167464 glutamate receptor, ionotropic, N-methyl D-aspartate 2A /FL=gb:U90277.1 gb:U09002.1 gb:NM_000833.2 NM_000833 glutamate receptor, ionotropic, N-methyl D-aspartate 2A GRIN2A 2903 NM_000833 /// NM_001134407 /// NM_001134408 /// XM_005255267 /// XM_005255268 0001964 // startle response // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0033058 // directional locomotion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0040011 // locomotion // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded /// 0097481 // neuronal postsynaptic density // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 206535_at NM_000340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000340.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), mRNA. /FEA=mRNA /GEN=SLC2A2 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 2 /DB_XREF=gi:4557850 /UG=Hs.167584 solute carrier family 2 (facilitated glucose transporter), member 2 /FL=gb:J03810.1 gb:NM_000340.1 NM_000340 solute carrier family 2 (facilitated glucose transporter), member 2 SLC2A2 6514 NM_000340 /// NM_001278658 /// NM_001278659 0005975 // carbohydrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0031018 // endocrine pancreas development // traceable author statement /// 0035428 // hexose transmembrane transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070837 // dehydroascorbic acid transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // not recorded /// 0015149 // hexose transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0033300 // dehydroascorbic acid transporter activity // inferred from electronic annotation /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 206536_s_at U32974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U32974.1 /DEF=Human IAP-like protein ILP mRNA, complete cds. /FEA=mRNA /PROD=IAP-like protein ILP /DB_XREF=gi:1016687 /UG=Hs.172777 baculoviral IAP repeat-containing 4 /FL=gb:U32974.1 gb:U45880.1 gb:NM_001167.1 U32974 X-linked inhibitor of apoptosis XIAP 331 NM_001167 /// NM_001204401 /// NR_037916 /// XM_006724754 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0008152 // metabolic process // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045088 // regulation of innate immune response // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0055070 // copper ion homeostasis // traceable author statement /// 0070424 // regulation of nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1902530 // positive regulation of protein linear polyubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206537_at NM_001167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001167.1 /DEF=Homo sapiens baculoviral IAP repeat-containing 4 (BIRC4), mRNA. /FEA=mRNA /GEN=BIRC4 /PROD=baculoviral IAP repeat-containing protein 4 /DB_XREF=gi:4502142 /UG=Hs.172777 baculoviral IAP repeat-containing 4 /FL=gb:U32974.1 gb:U45880.1 gb:NM_001167.1 NM_001167 X-linked inhibitor of apoptosis XIAP 331 NM_001167 /// NM_001204401 /// NR_037916 /// XM_006724754 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0008152 // metabolic process // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045088 // regulation of innate immune response // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0055070 // copper ion homeostasis // traceable author statement /// 0070424 // regulation of nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1902530 // positive regulation of protein linear polyubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206538_at NM_012219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012219.1 /DEF=Homo sapiens muscle RAS oncogene homolog (MRAS), mRNA. /FEA=mRNA /GEN=MRAS /PROD=muscle RAS oncogene homolog /DB_XREF=gi:6912513 /UG=Hs.173161 muscle RAS oncogene homolog /FL=gb:AF022080.1 gb:AF043938.1 gb:NM_012219.1 NM_012219 muscle RAS oncogene homolog MRAS 22808 NM_001085049 /// NM_001252090 /// NM_001252091 /// NM_001252092 /// NM_001252093 /// NM_012219 /// XM_005247228 /// XM_005247229 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 206539_s_at NM_023944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023944.1 /DEF=Homo sapiens cytochrome P450 isoform 4F12 (CYP4F12), mRNA. /FEA=mRNA /GEN=CYP4F12 /PROD=cytochrome P450 isoform 4F12 /DB_XREF=gi:13184045 /UG=Hs.180570 cytochrome P450 isoform 4F12 /FL=gb:AB035130.1 gb:AB035131.1 gb:AY008841.1 gb:NM_023944.1 NM_023944 cytochrome P450, family 4, subfamily F, polypeptide 12 CYP4F12 66002 NM_023944 /// NR_117085 /// XM_005260038 /// XM_006722848 /// XM_006722849 /// XM_006722850 0000038 // very long-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0001676 // long-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0003091 // renal water homeostasis // inferred from sequence or structural similarity /// 0003095 // pressure natriuresis // inferred from sequence or structural similarity /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // inferred from sequence or structural similarity /// 0019373 // epoxygenase P450 pathway // inferred from sequence or structural similarity /// 0030195 // negative regulation of blood coagulation // inferred from sequence or structural similarity /// 0036101 // leukotriene B4 catabolic process // inferred from sequence or structural similarity /// 0042360 // vitamin E metabolic process // inferred from sequence or structural similarity /// 0042371 // vitamin K biosynthetic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008392 // arachidonic acid epoxygenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047057 // vitamin-K-epoxide reductase (warfarin-sensitive) activity // inferred from sequence or structural similarity /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from sequence or structural similarity /// 0070330 // aromatase activity // inferred from electronic annotation 206540_at NM_024506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024506.1 /DEF=Homo sapiens hypothetical protein MGC10771 (MGC10771), mRNA. /FEA=mRNA /GEN=MGC10771 /PROD=hypothetical protein MGC10771 /DB_XREF=gi:13375639 /UG=Hs.181173 hypothetical protein MGC10771 /FL=gb:BC003523.1 gb:NM_024506.1 NM_024506 galactosidase, beta 1-like GLB1L 79411 NM_001286423 /// NM_001286427 /// NM_024506 /// XM_005246850 /// XM_005246851 /// XM_006712743 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009341 // beta-galactosidase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 206541_at NM_000892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000892.2 /DEF=Homo sapiens kallikrein B, plasma (Fletcher factor) 1 (KLKB1), mRNA. /FEA=mRNA /GEN=KLKB1 /PROD=plasma kallikrein B1 precursor /DB_XREF=gi:9257226 /UG=Hs.1901 kallikrein B, plasma (Fletcher factor) 1 /FL=gb:NM_000892.2 NM_000892 kallikrein B, plasma (Fletcher factor) 1 KLKB1 3818 NM_000892 /// XM_005262987 /// XM_006714213 0002542 // Factor XII activation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031638 // zymogen activation // traceable author statement /// 0031639 // plasminogen activation // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206542_s_at AV725365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV725365 /FEA=EST /DB_XREF=gi:10830680 /DB_XREF=est:AV725365 /CLONE=HTCCIF03 /UG=Hs.198296 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 /FL=gb:NM_003070.1 gb:D26155.1 AV725365 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 206543_at NM_003070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003070.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), mRNA. /FEA=mRNA /GEN=SMARCA2 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 2 /DB_XREF=gi:4507068 /UG=Hs.198296 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 /FL=gb:NM_003070.1 gb:D26155.1 NM_003070 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 206544_x_at NM_003070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003070.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), mRNA. /FEA=mRNA /GEN=SMARCA2 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 2 /DB_XREF=gi:4507068 /UG=Hs.198296 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 /FL=gb:NM_003070.1 gb:D26155.1 NM_003070 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 206545_at NM_006139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006139.1 /DEF=Homo sapiens CD28 antigen (Tp44) (CD28), mRNA. /FEA=mRNA /GEN=CD28 /PROD=CD28 antigen (Tp44) /DB_XREF=gi:5453610 /UG=Hs.1987 CD28 antigen (Tp44) /FL=gb:J02988.1 gb:NM_006139.1 gb:AF222342.1 NM_006139 CD28 molecule CD28 940 NM_001243077 /// NM_001243078 /// NM_006139 /// XM_006712862 0002863 // positive regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042089 // cytokine biosynthetic process // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // traceable author statement /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045066 // regulatory T cell differentiation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // non-traceable author statement /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0042802 // identical protein binding // non-traceable author statement 206546_at NM_014258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014258.1 /DEF=Homo sapiens synaptonemal complex protein 2 (SYCP2), mRNA. /FEA=mRNA /GEN=SYCP2 /PROD=synaptonemal complex protein 2 /DB_XREF=gi:7657634 /UG=Hs.202676 synaptonemal complex protein 2 /FL=gb:NM_014258.1 NM_014258 synaptonemal complex protein 2 SYCP2 10388 NM_014258 /// XM_005260247 /// XM_006723681 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007128 // meiotic prophase I // non-traceable author statement /// 0007130 // synaptonemal complex assembly // non-traceable author statement /// 0007140 // male meiosis // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048808 // male genitalia morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // non-traceable author statement /// 0000800 // lateral element // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206547_s_at NM_006240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006240.1 /DEF=Homo sapiens protein phosphatase, EF hand calcium-binding domain 1 (PPEF1), mRNA. /FEA=mRNA /GEN=PPEF1 /PROD=protein phosphatase, EF hand calcium-bindingdomain 1 /DB_XREF=gi:5453941 /UG=Hs.211589 protein phosphatase, EF hand calcium-binding domain 1 /FL=gb:AF023455.1 gb:NM_006240.1 NM_006240 protein phosphatase, EF-hand calcium binding domain 1 PPEF1 5475 NM_006240 /// NM_152223 /// NM_152224 /// NM_152225 /// NM_152226 /// XM_005274553 /// XM_005274554 /// XM_006724500 0006470 // protein dephosphorylation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0050906 // detection of stimulus involved in sensory perception // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206548_at NM_024880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024880.1 /DEF=Homo sapiens hypothetical protein FLJ23556 (FLJ23556), mRNA. /FEA=mRNA /GEN=FLJ23556 /PROD=hypothetical protein FLJ23556 /DB_XREF=gi:13376321 /UG=Hs.214039 hypothetical protein FLJ23556 /FL=gb:NM_024880.1 NM_024880 206549_at NM_002195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002195.1 /DEF=Homo sapiens insulin-like 4 (placenta) (INSL4), mRNA. /FEA=mRNA /GEN=INSL4 /PROD=insulin-like 4 precursor /DB_XREF=gi:4504710 /UG=Hs.21666 insulin-like 4 (placenta) /FL=gb:L34838.1 gb:NM_002195.1 NM_002195 insulin-like 4 (placenta) INSL4 3641 NM_002195 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005159 // insulin-like growth factor receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 206550_s_at NM_004298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004298.1 /DEF=Homo sapiens nucleoporin 155kD (NUP155), mRNA. /FEA=mRNA /GEN=NUP155 /PROD=nucleoporin 155kD /DB_XREF=gi:4758843 /UG=Hs.23255 nucleoporin 155kD /FL=gb:AB018334.1 gb:NM_004298.1 NM_004298 nucleoporin 155kDa NUP155 9631 NM_001278312 /// NM_004298 /// NM_153485 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from direct assay /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0086014 // atrial cardiac muscle cell action potential // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0017056 // structural constituent of nuclear pore // inferred from electronic annotation 206551_x_at NM_017644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017644.1 /DEF=Homo sapiens hypothetical protein FLJ20059 (FLJ20059), mRNA. /FEA=mRNA /GEN=FLJ20059 /PROD=hypothetical protein FLJ20059 /DB_XREF=gi:8923060 /UG=Hs.246875 hypothetical protein FLJ20059 /FL=gb:NM_017644.1 NM_017644 kelch-like family member 24 KLHL24 54800 NM_017644 /// XM_005247552 /// XM_005247553 /// XM_005247554 /// XM_005247555 /// XM_005247556 /// XM_006713674 /// XR_241499 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206552_s_at NM_003182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003182.1 /DEF=Homo sapiens tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K,neuropeptide gamma) (TAC1), transcript variant beta, mRNA. /FEA=mRNA /GEN=TAC1 /PROD=tachykinin 2 precursor, isoform beta /DB_XREF=gi:4507340 /UG=Hs.2563 tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K,neuropeptide gamma) /FL=gb:U37529.1 gb:NM_003182.1 NM_003182 tachykinin, precursor 1 TAC1 6863 NM_003182 /// NM_013996 /// NM_013997 /// NM_013998 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007217 // tachykinin receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007320 // insemination // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0046878 // positive regulation of saliva secretion // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 2000854 // positive regulation of corticosterone secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031835 // substance P receptor binding // inferred from electronic annotation 206553_at NM_002535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002535.1 /DEF=Homo sapiens 2-5oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA. /FEA=mRNA /GEN=OAS2 /PROD=2-5oligoadenylate synthetase 2, isoform p69 /DB_XREF=gi:4505484 /UG=Hs.264981 2-5oligoadenylate synthetase 2 /FL=gb:M87284.1 gb:NM_002535.1 NM_002535 2'-5'-oligoadenylate synthetase 2, 69/71kDa OAS2 4939 NM_001032731 /// NM_002535 /// NM_016817 0002376 // immune system process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from direct assay /// 0006401 // RNA catabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0018377 // protein myristoylation // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206554_x_at NM_006515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006515.1 /DEF=Homo sapiens SET domain and mariner transposase fusion gene (SETMAR), mRNA. /FEA=mRNA /GEN=SETMAR /PROD=SET domain and mariner transposase fusion gene /DB_XREF=gi:5730038 /UG=Hs.265855 SET domain and mariner transposase fusion gene /FL=gb:U80776.1 gb:AF054989.1 gb:NM_006515.1 NM_006515 SET domain and mariner transposase fusion gene SETMAR 6419 NM_001243723 /// NM_001276325 /// NM_006515 /// NR_024022 /// NR_075073 /// XM_006713292 /// XM_006713293 /// XM_006713294 /// XM_006713295 /// XM_006713296 /// XM_006713297 0000729 // DNA double-strand break processing // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006313 // transposition, DNA-mediated // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015074 // DNA integration // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from mutant phenotype /// 2001034 // positive regulation of double-strand break repair via nonhomologous end joining // inferred from direct assay /// 2001251 // negative regulation of chromosome organization // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from direct assay /// 0004803 // transposase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043566 // structure-specific DNA binding // inferred from direct assay /// 0043566 // structure-specific DNA binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206555_s_at NM_017736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017736.1 /DEF=Homo sapiens hypothetical protein FLJ20274 (FLJ20274), mRNA. /FEA=mRNA /GEN=FLJ20274 /PROD=hypothetical protein FLJ20274 /DB_XREF=gi:8923246 /UG=Hs.268371 hypothetical protein FLJ20274 /FL=gb:BC000448.1 gb:NM_017736.1 NM_017736 THUMP domain containing 1 THUMPD1 55623 NM_017736 /// XM_005255422 /// XM_005255424 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 206556_at NM_014410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014410.1 /DEF=Homo sapiens clusterin-like 1 (retinal) (CLUL1), mRNA. /FEA=mRNA /GEN=CLUL1 /PROD=clusterin-like 1 (retinal) /DB_XREF=gi:7657489 /UG=Hs.26886 clusterin-like 1 (retinal) /FL=gb:NM_014410.1 gb:D63813.1 NM_014410 clusterin-like 1 (retinal) CLUL1 27098 NM_001289036 /// NM_014410 /// NM_199167 /// XM_005258103 /// XM_005258104 /// XM_005258105 /// XM_006722322 0008219 // cell death // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 206557_at NM_024924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024924.1 /DEF=Homo sapiens hypothetical protein FLJ12985 (FLJ12985), mRNA. /FEA=mRNA /GEN=FLJ12985 /PROD=hypothetical protein FLJ12985 /DB_XREF=gi:13430873 /UG=Hs.270435 hypothetical protein FLJ12985 /FL=gb:NM_024924.1 NM_024924 zinc finger protein 702, pseudogene ZNF702P 79986 NM_024924 /// NR_003578 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206558_at NM_005069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005069.2 /DEF=Homo sapiens single-minded (Drosophila) homolog 2 (SIM2), transcript variant SIM2, mRNA. /FEA=mRNA /GEN=SIM2 /PROD=single-minded (Drosophila) homolog 2 longisoform /DB_XREF=gi:7108363 /UG=Hs.27311 single-minded (Drosophila) homolog 2 /FL=gb:U80456.1 gb:NM_005069.2 NM_005069 single-minded family bHLH transcription factor 2 SIM2 6493 NM_005069 /// NM_009586 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 206559_x_at NM_001403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001403.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 alpha 1-like 14 (EEF1A1L14), mRNA. /FEA=mRNA /GEN=EEF1A1L14 /PROD=eukaryotic translation elongation factor 1 alpha1-like 14 /DB_XREF=gi:4503472 /UG=Hs.274466 eukaryotic translation elongation factor 1 alpha 1-like 14 /FL=gb:NM_001403.1 NM_001403 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 206560_s_at NM_006533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006533.1 /DEF=Homo sapiens melanoma inhibitory activity (MIA), mRNA. /FEA=mRNA /GEN=MIA /PROD=melanoma inhibitory activity /DB_XREF=gi:5729924 /UG=Hs.279651 melanoma inhibitory activity /FL=gb:NM_006533.1 NM_006533 melanoma inhibitory activity MIA 8190 NM_001202553 /// NM_006533 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046323 // glucose import // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032593 // insulin-responsive compartment // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206561_s_at NM_020299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020299.1 /DEF=Homo sapiens aldo-keto reductase family 1, member B10 (aldose reductase) (AKR1B10), mRNA. /FEA=mRNA /GEN=AKR1B10 /PROD=aldo-keto reductase family 1, member B10 (aldosereductase) /DB_XREF=gi:13346507 /UG=Hs.282869 aldo-keto reductase family 1, member B10 (aldose reductase) /FL=gb:NM_020299.1 gb:AF052577.1 NM_020299 aldo-keto reductase family 1, member B10 (aldose reductase) AKR1B10 57016 NM_020299 /// XM_005250506 /// XM_006716060 0001523 // retinoid metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016488 // farnesol catabolic process // inferred from direct assay /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001758 // retinal dehydrogenase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0045550 // geranylgeranyl reductase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from direct assay 206562_s_at NM_001892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001892.1 /DEF=Homo sapiens casein kinase 1, alpha 1 (CSNK1A1), mRNA. /FEA=mRNA /GEN=CSNK1A1 /PROD=casein kinase 1, alpha 1 /DB_XREF=gi:4503088 /UG=Hs.283738 casein kinase 1, alpha 1 /FL=gb:NM_001892.1 gb:L37042.1 NM_001892 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206563_s_at AF348323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348323.1 /DEF=Homo sapiens nociceptin receptor (ORL1) mRNA, complete cds. /FEA=mRNA /GEN=ORL1 /PROD=nociceptin receptor /DB_XREF=gi:13022242 /UG=Hs.2859 opiate receptor-like 1 /FL=gb:U30185.1 gb:AF348323.1 gb:NM_000913.1 AF348323 opiate receptor-like 1 OPRL1 4987 NM_000913 /// NM_001200019 /// NM_182647 /// XM_005260206 /// XM_006723799 /// XM_006723800 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0007600 // sensory perception // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0038003 // opioid receptor signaling pathway // inferred from direct assay /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0001626 // nociceptin receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from genetic interaction /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206564_at NM_000913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000913.1 /DEF=Homo sapiens opiate receptor-like 1 (OPRL1), mRNA. /FEA=mRNA /GEN=OPRL1 /PROD=opiate receptor-like 1 /DB_XREF=gi:4505512 /UG=Hs.2859 opiate receptor-like 1 /FL=gb:U30185.1 gb:AF348323.1 gb:NM_000913.1 NM_000913 opiate receptor-like 1 OPRL1 4987 NM_000913 /// NM_001200019 /// NM_182647 /// XM_005260206 /// XM_006723799 /// XM_006723800 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0007600 // sensory perception // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0038003 // opioid receptor signaling pathway // inferred from direct assay /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0001626 // nociceptin receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from genetic interaction /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206565_x_at NM_006780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006780.1 /DEF=Homo sapiens SMA3 (SMA3), mRNA. /FEA=mRNA /GEN=SMA3 /PROD=SMA3 /DB_XREF=gi:5803174 /UG=Hs.289061 SMA3 /FL=gb:NM_006780.1 NM_006780 glucuronidase, beta pseudogene SMA4 11039 NM_006780 /// NM_021652 /// NR_024054 /// NR_029426 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 206566_at NM_003045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003045.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1), mRNA. /FEA=mRNA /GEN=SLC7A1 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 1 /DB_XREF=gi:4507046 /UG=Hs.2928 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 /FL=gb:AF078107.1 gb:NM_003045.1 NM_003045 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 SLC7A1 6541 NM_003045 /// XM_005266507 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015809 // arginine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation 206567_s_at NM_016436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016436.1 /DEF=Homo sapiens hepatocellular carcinoma-associated antigen 58 (LOC51230), mRNA. /FEA=mRNA /GEN=LOC51230 /PROD=hepatocellular carcinoma-associated antigen 58 /DB_XREF=gi:7705990 /UG=Hs.301055 hepatocellular carcinoma-associated antigen 58 /FL=gb:AF220416.1 gb:NM_016436.1 NM_016436 PHD finger protein 20 PHF20 51230 NM_016436 /// XM_005260421 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 206568_at NM_003284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003284.1 /DEF=Homo sapiens transition protein 1 (during histone to protamine replacement) (TNP1), mRNA. /FEA=mRNA /GEN=TNP1 /PROD=transition protein 1 (during histone toprotamine replacement) /DB_XREF=gi:4507628 /UG=Hs.3017 transition protein 1 (during histone to protamine replacement) /FL=gb:NM_003284.1 NM_003284 transition protein 1 (during histone to protamine replacement) TNP1 7141 NM_003284 0000012 // single strand break repair // inferred from direct assay /// 0006337 // nucleosome disassembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006342 // chromatin silencing // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from direct assay /// 0007289 // spermatid nucleus differentiation // traceable author statement /// 0007290 // spermatid nucleus elongation // inferred from mutant phenotype /// 0019953 // sexual reproduction // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from mutant phenotype /// 0035042 // fertilization, exchange of chromosomal proteins // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000786 // nucleosome // inferred from direct assay /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from mutant phenotype 206569_at NM_006850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006850.1 /DEF=Homo sapiens suppression of tumorigenicity 16 (melanoma differentiation) (ST16), mRNA. /FEA=mRNA /GEN=ST16 /PROD=suppression of tumorigenicity 16 (melanomadifferentiation) /DB_XREF=gi:5803085 /UG=Hs.315463 suppression of tumorigenicity 16 (melanoma differentiation) /FL=gb:U16261.1 gb:NM_006850.1 NM_006850 interleukin 24 IL24 11009 NM_001185156 /// NM_001185157 /// NM_001185158 /// NM_006850 /// NM_181339 /// XM_006711138 0006915 // apoptotic process // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0033136 // serine phosphorylation of STAT3 protein // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation 206570_s_at NM_002785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002785.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 11 (Note: redefinition of symbol) (PSG11), mRNA. /FEA=mRNA /GEN=PSG11 /PROD=pregnancy specific beta-1-glycoprotein 11 (Note:redefinition of symbol) /DB_XREF=gi:4506168 /UG=Hs.321450 pregnancy specific beta-1-glycoprotein 11 /FL=gb:NM_002785.1 gb:U25988.1 NM_002785 pregnancy specific beta-1-glycoprotein 11 PSG11 5680 NM_001113410 /// NM_002785 /// NM_203287 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 206571_s_at NM_004834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004834.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), mRNA. /FEA=mRNA /GEN=MAP4K4 /PROD=mitogen-activated protein kinase kinase kinasekinase 4 /DB_XREF=gi:4758523 /UG=Hs.3628 mitogen-activated protein kinase kinase kinase kinase 4 /FL=gb:AF096300.1 gb:NM_004834.1 NM_004834 mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4 9448 NM_001242559 /// NM_001242560 /// NM_004834 /// NM_145686 /// NM_145687 /// XM_005264044 /// XM_005264045 /// XM_005264046 /// XM_005264047 /// XM_005264048 /// XM_005264049 /// XM_005264050 /// XM_005264052 /// XM_005264053 /// XM_005264054 /// XM_005264055 /// XM_005264056 /// XM_005264057 /// XM_005264058 /// XM_005264059 /// XM_005264060 /// XM_005264061 /// XM_005264062 /// XM_005264063 /// XM_005264064 /// XM_005264065 /// XM_005264066 /// XM_005264068 /// XM_005264069 /// XM_005264071 /// XM_006712864 /// XM_006712865 /// XM_006712866 /// XM_006712867 /// XM_006712868 /// XM_006712869 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206572_x_at NM_003429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003429.1 /DEF=Homo sapiens zinc finger protein 85 (HPF4, HTF1) (ZNF85), mRNA. /FEA=mRNA /GEN=ZNF85 /PROD=zinc finger protein 85 (HPF4, HTF1) /DB_XREF=gi:4508038 /UG=Hs.37138 zinc finger protein 85 (HPF4, HTF1) /FL=gb:U35376.1 gb:NM_003429.1 NM_003429 zinc finger protein 85 ZNF85 7639 NM_001256171 /// NM_001256172 /// NM_001256173 /// NM_003429 /// NR_045830 /// XM_006722876 /// XM_006722877 /// XM_006726230 /// XM_006726231 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206573_at NM_004519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004519.1 /DEF=Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), mRNA. /FEA=mRNA /GEN=KCNQ3 /PROD=potassium voltage-gated channel, KQT-likesubfamily, member 3 /DB_XREF=gi:4758629 /UG=Hs.40866 potassium voltage-gated channel, KQT-like subfamily, member 3 /FL=gb:NM_004519.1 NM_004519 potassium voltage-gated channel, KQT-like subfamily, member 3 KCNQ3 3786 NM_001204824 /// NM_004519 /// XM_005250913 /// XM_005250914 /// XM_006716554 /// XM_006716555 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement 206574_s_at NM_007079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007079.1 /DEF=Homo sapiens protein tyrosine phosphatase type IVA, member 3 (PTP4A3), mRNA. /FEA=mRNA /GEN=PTP4A3 /PROD=protein tyrosine phosphatase type IVA, member 3 /DB_XREF=gi:6857821 /UG=Hs.43666 protein tyrosine phosphatase type IVA, member 3 /FL=gb:AF041434.1 gb:NM_007079.1 NM_007079 protein tyrosine phosphatase type IVA, member 3 PTP4A3 11156 NM_007079 /// NM_032611 /// XM_005250762 /// XM_005250763 /// XM_005250764 /// XM_005250766 /// XM_005250767 /// XM_006716499 /// XM_006716500 /// XM_006725100 /// XM_006725101 /// XM_006725102 /// XM_006725103 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 206575_at NM_003159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003159.1 /DEF=Homo sapiens serinethreonine kinase 9 (STK9), mRNA. /FEA=mRNA /GEN=STK9 /PROD=serinethreonine kinase 9 /DB_XREF=gi:4507280 /UG=Hs.50905 serinethreonine kinase 9 /FL=gb:NM_003159.1 NM_003159 cyclin-dependent kinase-like 5 CDKL5 6792 NM_001037343 /// NM_003159 /// XM_005274584 /// XM_005274585 /// XM_006724511 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050773 // regulation of dendrite development // inferred from sequence or structural similarity /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0032839 // dendrite cytoplasm // inferred from sequence or structural similarity /// 0044294 // dendritic growth cone // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity 206576_s_at NM_001712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001712.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), mRNA. /FEA=mRNA /GEN=CEACAM1 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 1 (biliary glycoprotein) /DB_XREF=gi:4502404 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:NM_001712.1 NM_001712 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) CEACAM1 634 NM_001024912 /// NM_001184813 /// NM_001184815 /// NM_001184816 /// NM_001205344 /// NM_001712 0001525 // angiogenesis // non-traceable author statement /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 206577_at NM_003381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003381.1 /DEF=Homo sapiens vasoactive intestinal peptide (VIP), mRNA. /FEA=mRNA /GEN=VIP /PROD=vasoactive intestinal peptide /DB_XREF=gi:4507896 /UG=Hs.53973 vasoactive intestinal peptide /FL=gb:M36634.1 gb:NM_003381.1 NM_003381 vasoactive intestinal peptide VIP 7432 NM_003381 /// NM_194435 /// XM_005267135 /// XM_006715562 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007589 // body fluid secretion // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from direct assay /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206578_at NM_004387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004387.1 /DEF=Homo sapiens cardiac-specific homeo box (CSX), mRNA. /FEA=mRNA /GEN=CSX /PROD=cardiac-specific homeo box /DB_XREF=gi:4758089 /UG=Hs.54473 cardiac-specific homeo box /FL=gb:U34962.1 gb:AB021133.1 gb:NM_004387.1 NM_004387 NK2 homeobox 5 NKX2-5 1482 NM_001166175 /// NM_001166176 /// NM_004387 /// XM_005265820 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from mutant phenotype /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from mutant phenotype /// 0003162 // atrioventricular node development // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0003168 // Purkinje myocyte differentiation // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from electronic annotation /// 0003211 // cardiac ventricle formation // inferred from electronic annotation /// 0003221 // right ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003285 // septum secundum development // inferred from mutant phenotype /// 0003342 // proepicardium development // inferred from electronic annotation /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from mutant phenotype /// 0010735 // positive regulation of transcription via serum response element binding // inferred from sequence or structural similarity /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045823 // positive regulation of heart contraction // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from mutant phenotype /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051891 // positive regulation of cardioblast differentiation // inferred from sequence or structural similarity /// 0055005 // ventricular cardiac myofibril assembly // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055008 // cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0055014 // atrial cardiac muscle cell development // inferred from sequence or structural similarity /// 0055015 // ventricular cardiac muscle cell development // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060043 // regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from mutant phenotype /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060928 // atrioventricular node cell development // inferred from electronic annotation /// 0060929 // atrioventricular node cell fate commitment // inferred from electronic annotation /// 0060971 // embryonic heart tube left/right pattern formation // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 1901387 // positive regulation of voltage-gated calcium channel activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0010736 // serum response element binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 206579_at NM_006298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006298.1 /DEF=Homo sapiens zinc finger protein 192 (ZNF192), mRNA. /FEA=mRNA /GEN=ZNF192 /PROD=zinc finger protein 192 /DB_XREF=gi:5454177 /UG=Hs.57679 zinc finger protein 192 /FL=gb:U57796.1 gb:NM_006298.1 NM_006298 zinc finger with KRAB and SCAN domains 8 ZKSCAN8 7745 NM_001278119 /// NM_001278121 /// NM_001278122 /// NM_006298 /// XM_005249382 /// XM_005249383 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206580_s_at NM_016938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016938.1 /DEF=Homo sapiens EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2), mRNA. /FEA=mRNA /GEN=EFEMP2 /PROD=EGF-containing fibulin-like extracellular matrixprotein 2 /DB_XREF=gi:8393298 /UG=Hs.6059 EGF-containing fibulin-like extracellular matrix protein 2 /FL=gb:AF093119.1 gb:AF109121.1 gb:NM_016938.1 NM_016938 EGF containing fibulin-like extracellular matrix protein 2 EFEMP2 30008 NM_016938 /// NR_037718 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206581_at NM_001717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001717.1 /DEF=Homo sapiens basonuclin (BNC), mRNA. /FEA=mRNA /GEN=BNC /PROD=basonuclin /DB_XREF=gi:4502438 /UG=Hs.64025 basonuclin /FL=gb:L03427.1 gb:NM_001717.1 NM_001717 basonuclin 1 BNC1 646 NM_001717 /// XM_005272447 /// XM_006720641 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206582_s_at NM_005682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005682.1 /DEF=Homo sapiens G protein-coupled receptor 56 (GPR56), mRNA. /FEA=mRNA /GEN=GPR56 /PROD=G protein-coupled receptor 56 /DB_XREF=gi:5031724 /UG=Hs.6527 G protein-coupled receptor 56 /FL=gb:AF106858.1 gb:NM_005682.1 NM_005682 G protein-coupled receptor 56 GPR56 9289 NM_001145770 /// NM_001145771 /// NM_001145772 /// NM_001145773 /// NM_001145774 /// NM_001290142 /// NM_001290143 /// NM_001290144 /// NM_005682 /// NM_201524 /// NM_201525 /// XM_005256237 /// XM_005256238 /// XM_005256239 /// XM_005256240 /// XM_005256241 /// XM_005256242 /// XM_005256243 /// XM_005256244 /// XM_005256245 /// XM_005256246 /// XM_005256247 /// XM_005256248 /// XM_005256249 /// XM_005256251 /// XM_005256252 /// XM_005256253 /// XM_005256254 /// XM_005256255 /// XM_006721338 /// XM_006721339 /// XM_006721340 /// XM_006721341 /// XM_006721342 /// XM_006721343 /// XM_006721344 /// XM_006721345 /// XM_006721346 /// XM_006721347 0001525 // angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010573 // vascular endothelial growth factor production // inferred from direct assay /// 0021801 // cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from direct assay /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097451 // glial limiting end-foot // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0050840 // extracellular matrix binding // inferred from sequence or structural similarity 206583_at NM_017776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017776.1 /DEF=Homo sapiens hypothetical protein FLJ20344 (FLJ20344), mRNA. /FEA=mRNA /GEN=FLJ20344 /PROD=hypothetical protein FLJ20344 /DB_XREF=gi:8923321 /UG=Hs.68318 hypothetical protein FLJ20344 /FL=gb:NM_017776.1 NM_017776 KRAB box domain containing 4 KRBOX4 55634 NM_001129898 /// NM_001129899 /// NM_001129900 /// NM_017776 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 206584_at NM_015364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015364.1 /DEF=Homo sapiens MD-2 protein (MD-2), mRNA. /FEA=mRNA /GEN=MD-2 /PROD=MD-2 protein /DB_XREF=gi:7662503 /UG=Hs.69328 MD-2 protein /FL=gb:AB018549.1 gb:NM_015364.1 gb:AF168121.1 NM_015364 lymphocyte antigen 96 LY96 23643 NM_001195797 /// NM_015364 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement 206585_at NM_005664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005664.1 /DEF=Homo sapiens makorin, ring finger protein, 3 (MKRN3), mRNA. /FEA=mRNA /GEN=MKRN3 /PROD=makorin, ring finger protein, 3 /DB_XREF=gi:5032242 /UG=Hs.72964 makorin, ring finger protein, 3 /FL=gb:NM_005664.1 NM_005664 makorin ring finger protein 3 MKRN3 7681 NM_005664 0016567 // protein ubiquitination // inferred from electronic annotation 0030529 // ribonucleoprotein complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206586_at NM_001841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001841.1 /DEF=Homo sapiens cannabinoid receptor 2 (macrophage) (CNR2), mRNA. /FEA=mRNA /GEN=CNR2 /PROD=cannabinoid receptor 2 (macrophage) /DB_XREF=gi:4502928 /UG=Hs.73037 cannabinoid receptor 2 (macrophage) /FL=gb:NM_001841.1 NM_001841 cannabinoid receptor 2 (macrophage) CNR2 1269 NM_001841 /// XM_005245736 /// XM_005245737 /// XM_005245738 0001975 // response to amphetamine // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033004 // negative regulation of mast cell activation // inferred from electronic annotation /// 0038171 // cannabinoid signaling pathway // inferred from electronic annotation /// 0045759 // negative regulation of action potential // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004949 // cannabinoid receptor activity // inferred from electronic annotation 206587_at NM_006584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006584.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 6B (zeta 2) (CCT6B), mRNA. /FEA=mRNA /GEN=CCT6B /PROD=chaperonin containing TCP1, subunit 6B (zeta 2) /DB_XREF=gi:5729760 /UG=Hs.73072 chaperonin containing TCP1, subunit 6B (zeta 2) /FL=gb:D78333.1 gb:NM_006584.1 NM_006584 chaperonin containing TCP1, subunit 6B (zeta 2) CCT6B 10693 NM_001193529 /// NM_001193530 /// NM_006584 /// XM_006721641 /// XM_006721642 0006457 // protein folding // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0015031 // protein transport // traceable author statement /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0051131 // chaperone-mediated protein complex assembly // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008565 // protein transporter activity // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 206588_at NM_001351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001351.1 /DEF=Homo sapiens deleted in azoospermia-like (DAZL), mRNA. /FEA=mRNA /GEN=DAZL /PROD=deleted in azoospermia-like /DB_XREF=gi:4503258 /UG=Hs.73078 deleted in azoospermia-like /FL=gb:U65918.1 gb:U66078.1 gb:NM_001351.1 gb:U66726.2 NM_001351 deleted in azoospermia-like DAZL 1618 NM_001190811 /// NM_001351 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045836 // positive regulation of meiosis // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation 206589_at NM_005263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005263.1 /DEF=Homo sapiens growth factor independent 1 (GFI1), mRNA. /FEA=mRNA /GEN=GFI1 /PROD=growth factor independent 1 /DB_XREF=gi:4885266 /UG=Hs.73172 growth factor independent 1 /FL=gb:U67369.1 gb:NM_005263.1 NM_005263 growth factor independent 1 transcription repressor GFI1 2672 NM_001127215 /// NM_001127216 /// NM_005263 /// XM_005270749 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0009996 // negative regulation of cell fate specification // inferred from electronic annotation /// 0010956 // negative regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0010957 // negative regulation of vitamin D biosynthetic process // inferred by curator /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034121 // regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042660 // positive regulation of cell fate specification // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0070105 // positive regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206590_x_at NM_000795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000795.1 /DEF=Homo sapiens dopamine receptor D2 (DRD2), mRNA. /FEA=mRNA /GEN=DRD2 /PROD=dopamine receptor D2 /DB_XREF=gi:4503384 /UG=Hs.73893 dopamine receptor D2 /FL=gb:M29066.1 gb:NM_000795.1 gb:AF176812.1 gb:NM_016574.1 NM_000795 dopamine receptor D2 DRD2 1813 NM_000795 /// NM_016574 /// XM_005271425 /// XM_006718774 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from sequence or structural similarity /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014854 // response to inactivity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0021984 // adenohypophysis development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0034776 // response to histamine // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from sequence or structural similarity /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046717 // acid secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from sequence or structural similarity /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060124 // positive regulation of growth hormone secretion // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from genetic interaction /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation /// 1900273 // positive regulation of long-term synaptic potentiation // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0035240 // dopamine binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206591_at NM_000448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000448.1 /DEF=Homo sapiens recombination activating gene 1 (RAG1), mRNA. /FEA=mRNA /GEN=RAG1 /PROD=recombination activating gene 1 /DB_XREF=gi:4557840 /UG=Hs.73958 recombination activating gene 1 /FL=gb:M29474.1 gb:NM_000448.1 NM_000448 recombination activating gene 1 RAG1 5896 NM_000448 /// XM_005253041 0002250 // adaptive immune response // inferred from electronic annotation /// 0002331 // pre-B cell allelic exclusion // inferred from sequence or structural similarity /// 0006310 // DNA recombination // traceable author statement /// 0006955 // immune response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010390 // histone monoubiquitination // inferred from sequence or structural similarity /// 0016265 // death // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity /// 0070233 // negative regulation of T cell apoptotic process // inferred from electronic annotation /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from sequence or structural similarity 206592_s_at NM_003938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003938.1 /DEF=Homo sapiens adaptor-related protein complex 3, delta 1 subunit (AP3D1), mRNA. /FEA=mRNA /GEN=AP3D1 /PROD=adaptor-related protein complex 3, delta 1subunit /DB_XREF=gi:4501976 /UG=Hs.75056 adaptor-related protein complex 3, delta 1 subunit /FL=gb:U91930.1 gb:NM_003938.1 NM_003938 adaptor-related protein complex 3, delta 1 subunit AP3D1 8943 NM_001077523 /// NM_001261826 /// NM_003938 /// XM_006722932 0006726 // eye pigment biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred by curator /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0048499 // synaptic vesicle membrane organization // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0061088 // regulation of sequestering of zinc ion // inferred from mutant phenotype /// 0072657 // protein localization to membrane // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 206593_s_at NM_006752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006752.1 /DEF=Homo sapiens surfeit 5 (SURF5), mRNA. /FEA=mRNA /GEN=SURF5 /PROD=surfeit 5 /DB_XREF=gi:5803182 /UG=Hs.78354 surfeit 5 /FL=gb:NM_006752.1 NM_006752 mediator complex subunit 22 MED22 6837 NM_006752 /// NM_133640 /// NM_181491 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206594_at NM_015148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015148.1 /DEF=Homo sapiens KIAA0135 protein (KIAA0135), mRNA. /FEA=mRNA /GEN=KIAA0135 /PROD=KIAA0135 protein /DB_XREF=gi:8923825 /UG=Hs.79337 KIAA0135 protein /FL=gb:NM_015148.1 NM_015148 PAS domain containing serine/threonine kinase PASK 23178 NM_001252119 /// NM_001252120 /// NM_001252122 /// NM_001252124 /// NM_015148 /// XM_005246990 /// XM_005246991 /// XR_427079 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045727 // positive regulation of translation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0070092 // regulation of glucagon secretion // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 206595_at NM_001323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001323.1 /DEF=Homo sapiens cystatin EM (CST6), mRNA. /FEA=mRNA /GEN=CST6 /PROD=cystatin M /DB_XREF=gi:4503112 /UG=Hs.83393 cystatin EM /FL=gb:U62800.1 gb:U81233.1 gb:NM_001323.1 NM_001323 cystatin E/M CST6 1474 NM_001323 0008544 // epidermis development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0001533 // cornified envelope // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206596_s_at M81840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81840.1 /DEF=Human NRL gene product mRNA, complete cds. /FEA=mRNA /GEN=nrl /DB_XREF=gi:189293 /UG=Hs.89606 neural retina leucine zipper /FL=gb:M81840.1 gb:M95925.1 gb:NM_006177.1 M81840 neural retina leucine zipper NRL 4901 NM_006177 /// XM_005267708 /// XM_005267709 /// XM_005267710 /// XM_006720154 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007468 // regulation of rhodopsin gene expression // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0045872 // positive regulation of rhodopsin gene expression // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206597_at NM_006177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006177.1 /DEF=Homo sapiens neural retina leucine zipper (NRL), mRNA. /FEA=mRNA /GEN=NRL /PROD=neural retina leucine zipper /DB_XREF=gi:5453801 /UG=Hs.89606 neural retina leucine zipper /FL=gb:M81840.1 gb:M95925.1 gb:NM_006177.1 NM_006177 neural retina leucine zipper NRL 4901 NM_006177 /// XM_005267708 /// XM_005267709 /// XM_005267710 /// XM_006720154 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007468 // regulation of rhodopsin gene expression // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0045872 // positive regulation of rhodopsin gene expression // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206598_at NM_000207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000207.1 /DEF=Homo sapiens insulin (INS), mRNA. /FEA=mRNA /GEN=INS /PROD=proinsulin precursor /DB_XREF=gi:4557670 /UG=Hs.89832 insulin /FL=gb:BC005255.1 gb:NM_000207.1 NM_000207 insulin INS 3630 NM_000207 /// NM_001185097 /// NM_001185098 /// NM_001291897 0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005576 // extracellular region // inferred by curator /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred by curator /// 0005179 // hormone activity // inferred from mutant phenotype /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation /// 0030546 // receptor activator activity // inferred from electronic annotation /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 206599_at NM_004695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004695.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 5 (SLC16A5), mRNA. /FEA=mRNA /GEN=SLC16A5 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 5 /DB_XREF=gi:4759115 /UG=Hs.90911 solute carrier family 16 (monocarboxylic acid transporters), member 5 /FL=gb:U59299.1 gb:NM_004695.1 NM_004695 solute carrier family 16 (monocarboxylate transporter), member 5 SLC16A5 9121 NM_001271765 /// NM_004695 /// XM_005257790 /// XM_005257791 /// XM_006722170 0006810 // transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation 206600_s_at NM_004695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004695.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 5 (SLC16A5), mRNA. /FEA=mRNA /GEN=SLC16A5 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 5 /DB_XREF=gi:4759115 /UG=Hs.90911 solute carrier family 16 (monocarboxylic acid transporters), member 5 /FL=gb:U59299.1 gb:NM_004695.1 NM_004695 solute carrier family 16 (monocarboxylate transporter), member 5 SLC16A5 9121 NM_001271765 /// NM_004695 /// XM_005257790 /// XM_005257791 /// XM_006722170 0006810 // transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation 206601_s_at BC005124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005124.1 /DEF=Homo sapiens, homeo box D3, clone MGC:10470, mRNA, complete cds. /FEA=mRNA /PROD=homeo box D3 /DB_XREF=gi:13477300 /UG=Hs.93574 homeo box D3 /FL=gb:BC005124.1 gb:NM_006898.2 BC005124 homeobox D3 /// homeobox D4 /// uncharacterized LOC401021 HOXD3 /// HOXD4 /// LOC401021 3232 /// 3233 /// 401021 NM_006898 /// NM_014621 /// XM_005246509 /// XM_005246510 /// XM_005246511 /// XM_005246512 /// XM_005246513 /// XM_005246514 /// XM_006712477 /// XR_249307 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021615 // glossopharyngeal nerve morphogenesis // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206602_s_at NM_006898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006898.2 /DEF=Homo sapiens homeo box D3 (HOXD3), mRNA. /FEA=CDS /GEN=HOXD3 /PROD=homeo box D3 /DB_XREF=gi:6325468 /UG=Hs.93574 homeo box D3 /FL=gb:BC005124.1 gb:NM_006898.2 NM_006898 homeobox D3 /// homeobox D4 /// uncharacterized LOC401021 HOXD3 /// HOXD4 /// LOC401021 3232 /// 3233 /// 401021 NM_006898 /// NM_014621 /// XM_005246509 /// XM_005246510 /// XM_005246511 /// XM_005246512 /// XM_005246513 /// XM_005246514 /// XM_006712477 /// XR_249307 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021615 // glossopharyngeal nerve morphogenesis // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206603_at NM_001042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001042.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), mRNA. /FEA=mRNA /GEN=SLC2A4 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 4 /DB_XREF=gi:4507010 /UG=Hs.95958 solute carrier family 2 (facilitated glucose transporter), member 4 /FL=gb:M20747.1 gb:NM_001042.1 NM_001042 solute carrier family 2 (facilitated glucose transporter), member 4 SLC2A4 6517 NM_001042 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0010021 // amylopectin biosynthetic process // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046323 // glucose import // non-traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0071470 // cellular response to osmotic stress // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0032593 // insulin-responsive compartment // inferred from direct assay /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 206604_at NM_004561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004561.1 /DEF=Homo sapiens ovo (Drosophila) homolog-like 1 (OVOL1), mRNA. /FEA=mRNA /GEN=OVOL1 /PROD=ovo (Drosophila) homolog-like 1 /DB_XREF=gi:4758857 /UG=Hs.97905 ovo (Drosophila) homolog-like 1 /FL=gb:AF016045.1 gb:NM_004561.1 NM_004561 ovo-like zinc finger 1 OVOL1 5017 NM_004561 /// XM_005274017 /// XM_005274018 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009913 // epidermal cell differentiation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051729 // germline cell cycle switching, mitotic to meiotic cell cycle // inferred from electronic annotation /// 1901994 // negative regulation of meiotic cell cycle phase transition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206605_at NM_006025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006025.1 /DEF=Homo sapiens protease, serine, 22 (P11), mRNA. /FEA=mRNA /GEN=P11 /PROD=protease, serine, 22 /DB_XREF=gi:5174622 /UG=Hs.997 protease, serine, 22 /FL=gb:M32402.1 gb:NM_006025.1 NM_006025 endonuclease, polyU-specific ENDOU 8909 NM_001172439 /// NM_001172440 /// NM_006025 0006508 // proteolysis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from expression pattern /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0008083 // growth factor activity // non-traceable author statement /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0030145 // manganese ion binding // traceable author statement /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206606_at NM_000236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000236.1 /DEF=Homo sapiens lipase, hepatic (LIPC), mRNA. /FEA=mRNA /GEN=LIPC /PROD=lipase C precursor /DB_XREF=gi:4557722 /UG=Hs.9994 lipase, hepatic /FL=gb:D83548.1 gb:J03540.1 gb:J03895.1 gb:NM_000236.1 NM_000236 lipase, hepatic LIPC 3990 NM_000236 /// XM_005254372 /// XM_005254374 /// XM_006720501 /// XM_006720502 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034373 // intermediate-density lipoprotein particle remodeling // traceable author statement /// 0034374 // low-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034382 // chylomicron remnant clearance // traceable author statement /// 0034638 // phosphatidylcholine catabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred by curator /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004620 // phospholipase activity // traceable author statement /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016298 // lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from sequence or structural similarity /// 0034185 // apolipoprotein binding // inferred from sequence or structural similarity 206607_at NM_005188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005188.1 /DEF=Homo sapiens Cas-Br-M (murine) ecotropic retroviral transforming sequence (CBL), mRNA. /FEA=mRNA /GEN=CBL /PROD=Cas-Br-M (murine) ecotropic retroviraltransforming sequence /DB_XREF=gi:4885116 /UG=Hs.99980 Cas-Br-M (murine) ecotropic retroviral transforming sequence /FL=gb:NM_005188.1 NM_005188 Cbl proto-oncogene, E3 ubiquitin protein ligase CBL 867 NM_005188 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0023051 // regulation of signaling // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from sequence or structural similarity 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 206608_s_at NM_020366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020366.1 /DEF=Homo sapiens retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1), mRNA. /FEA=mRNA /GEN=RPGRIP1 /PROD=retinitis pigmentosa GTPase regulatorinteracting protein 1 /DB_XREF=gi:9966834 /UG=Hs.131917 retinitis pigmentosa GTPase regulator interacting protein 1 /FL=gb:AF260257.1 gb:AF227257.1 gb:NM_020366.1 NM_020366 retinitis pigmentosa GTPase regulator interacting protein 1 RPGRIP1 57096 NM_020366 /// XM_005267879 /// XM_005267880 /// XM_005267881 /// XM_006720208 /// XM_006720209 /// XM_006720210 0007601 // visual perception // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206609_at NM_005462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005462.1 /DEF=Homo sapiens melanoma antigen, family C, 1 (MAGEC1), mRNA. /FEA=mRNA /GEN=MAGEC1 /PROD=melanoma antigen, family C, 1 /DB_XREF=gi:4885474 /UG=Hs.132194 melanoma antigen, family C, 1 /FL=gb:AF056334.1 gb:NM_005462.1 NM_005462 melanoma antigen family C, 1 MAGEC1 9947 NM_005462 /// XM_003846772 0005515 // protein binding // inferred from physical interaction 206610_s_at NM_000128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000128.2 /DEF=Homo sapiens coagulation factor XI (plasma thromboplastin antecedent) (F11), transcript variant 1, mRNA. /FEA=mRNA /GEN=F11 /PROD=plasma coagulation factor XI precursor, isoforma /DB_XREF=gi:9961351 /UG=Hs.1430 coagulation factor XI (plasma thromboplastin antecedent) /FL=gb:M13142.1 gb:NM_000128.2 NM_000128 coagulation factor XI F11 2160 NM_000128 /// NM_019559 /// XM_005262821 /// XM_005262822 /// XM_005262823 /// XM_005262824 /// XM_005262825 /// XM_006714137 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from direct assay /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070009 // serine-type aminopeptidase activity // inferred from electronic annotation 206611_at NM_013310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013310.1 /DEF=Homo sapiens hypothetical protein (AF038169), mRNA. /FEA=mRNA /GEN=AF038169 /PROD=hypothetical protein /DB_XREF=gi:9558718 /UG=Hs.145567 hypothetical protein /FL=gb:AF038169.1 gb:NM_013310.1 NM_013310 chromosome 2 open reading frame 27A C2orf27A 29798 NM_013310 /// XM_005263649 /// XM_006724987 /// XM_006724988 206612_at NM_000727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000727.1 /DEF=Homo sapiens calcium channel, voltage-dependent, gamma subunit 1 (CACNG1), mRNA. /FEA=mRNA /GEN=CACNG1 /PROD=calcium channel, voltage-dependent, gammasubunit 1 /DB_XREF=gi:4502538 /UG=Hs.147989 calcium channel, voltage-dependent, gamma subunit 1 /FL=gb:L07738.1 gb:NM_000727.1 NM_000727 calcium channel, voltage-dependent, gamma subunit 1 CACNG1 786 NM_000727 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070296 // sarcoplasmic reticulum calcium ion transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation 206613_s_at NM_005681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005681.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD (TAF1A), mRNA. /FEA=mRNA /GEN=TAF1A /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase I, A, 48kD /DB_XREF=gi:5032142 /UG=Hs.153088 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD /FL=gb:NM_005681.1 gb:L39060.1 NM_005681 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa TAF1A 9015 NM_001201536 /// NM_005681 /// NM_139352 /// XM_005273343 /// XM_006711612 /// XM_006711613 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0000120 // RNA polymerase I transcription factor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206614_at NM_000557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000557.2 /DEF=Homo sapiens growth differentiation factor 5 (cartilage-derived morphogenetic protein-1) (GDF5), mRNA. /FEA=mRNA /GEN=GDF5 /PROD=growth differentiation factor 5 preproprotein /DB_XREF=gi:5123452 /UG=Hs.1573 growth differentiation factor 5 (cartilage-derived morphogenetic protein-1) /FL=gb:NM_000557.2 gb:U13660.1 NM_000557 growth differentiation factor 5 GDF5 8200 NM_000557 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 206615_s_at NM_021723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021723.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 22 (ADAM22), mRNA. /FEA=mRNA /GEN=ADAM22 /PROD=a disintegrin and metalloproteinase domain 22,isoform 1 preproprotein /DB_XREF=gi:11497046 /UG=Hs.158052 a disintegrin and metalloproteinase domain 22 /FL=gb:NM_021723.1 gb:AF155382.1 NM_021723 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 206616_s_at AF155382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155382.1 /DEF=Homo sapiens metalloprotease-like, disintegrin-like, cysteine-rich protein 2 epsilon (ADAM22) mRNA, complete cds. /FEA=mRNA /GEN=ADAM22 /PROD=metalloprotease-like, disintegrin-like,cysteine-rich protein 2 epsilon /DB_XREF=gi:8132434 /UG=Hs.158052 a disintegrin and metalloproteinase domain 22 /FL=gb:NM_021723.1 gb:AF155382.1 AF155382 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 206617_s_at NM_002910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002910.4 /DEF=Homo sapiens renin-binding protein (RENBP), mRNA. /FEA=mRNA /GEN=RENBP /PROD=renin-binding protein /DB_XREF=gi:11496987 /UG=Hs.158331 renin-binding protein /FL=gb:NM_002910.4 gb:D10232.1 NM_002910 renin binding protein RENBP 5973 NM_002910 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006051 // N-acetylmannosamine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004476 // mannose-6-phosphate isomerase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050121 // N-acylglucosamine 2-epimerase activity // inferred from sequence or structural similarity 206618_at NM_003855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003855.1 /DEF=Homo sapiens interleukin 18 receptor 1 (IL18R1), mRNA. /FEA=mRNA /GEN=IL18R1 /PROD=interleukin 18 receptor 1 /DB_XREF=gi:4504654 /UG=Hs.159301 interleukin 18 receptor 1 /FL=gb:U43672.1 gb:NM_003855.1 NM_003855 interleukin 18 receptor 1 IL18R1 8809 NM_001282399 /// NM_003855 /// XM_005264039 /// XM_005264040 /// XM_006712823 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030101 // natural killer cell activation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0035655 // interleukin-18-mediated signaling pathway // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0045063 // T-helper 1 cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042008 // interleukin-18 receptor activity // inferred from electronic annotation 206619_at NM_014420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014420.1 /DEF=Homo sapiens dickkopf (Xenopus laevis) homolog 4 (DKK4), mRNA. /FEA=mRNA /GEN=DKK4 /PROD=dickkopf (Xenopus laevis) homolog 4 /DB_XREF=gi:7657024 /UG=Hs.159311 dickkopf (Xenopus laevis) homolog 4 /FL=gb:AB017788.1 gb:AF177397.1 gb:NM_014420.1 NM_014420 dickkopf WNT signaling pathway inhibitor 4 DKK4 27121 NM_014420 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 206620_at NM_006613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006613.1 /DEF=Homo sapiens GRB2-related adaptor protein (GRAP), mRNA. /FEA=mRNA /GEN=GRAP /PROD=GRB2-related adaptor protein /DB_XREF=gi:5729855 /UG=Hs.159517 GRB2-related adaptor protein /FL=gb:U52518.1 gb:NM_006613.1 NM_006613 GRB2-related adaptor protein GRAP 10750 NM_006613 /// XM_005256425 /// XM_005256426 0007265 // Ras protein signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206621_s_at NM_022170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022170.1 /DEF=Homo sapiens Williams-Beuren syndrome chromosome region 1 (WBSCR1), mRNA. /FEA=mRNA /GEN=WBSCR1 /PROD=eukaryotic translation initiation factor 4H /DB_XREF=gi:11559922 /UG=Hs.180900 Williams-Beuren syndrome chromosome region 1 /FL=gb:NM_022170.1 NM_022170 eukaryotic translation initiation factor 4H EIF4H 7458 NM_022170 /// NM_031992 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 206622_at NM_007117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007117.1 /DEF=Homo sapiens thyrotropin-releasing hormone (TRH), mRNA. /FEA=mRNA /GEN=TRH /PROD=thyrotropin-releasing hormone /DB_XREF=gi:6005919 /UG=Hs.182231 thyrotropin-releasing hormone /FL=gb:NM_007117.1 NM_007117 thyrotropin-releasing hormone TRH 7200 NM_007117 0001666 // response to hypoxia // inferred from electronic annotation /// 0001692 // histamine metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008437 // thyrotropin-releasing hormone activity // inferred from electronic annotation 206623_at NM_000440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000440.1 /DEF=Homo sapiens phosphodiesterase 6A, cGMP-specific, rod, alpha (PDE6A), mRNA. /FEA=mRNA /GEN=PDE6A /PROD=phosphodiesterase 6A, alpha subunit /DB_XREF=gi:4585863 /UG=Hs.182240 phosphodiesterase 6A, cGMP-specific, rod, alpha /FL=gb:M26061.1 gb:NM_000440.1 NM_000440 phosphodiesterase 6A, cGMP-specific, rod, alpha PDE6A 5145 NM_000440 /// XR_245856 /// XR_427777 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0046037 // GMP metabolic process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from mutant phenotype 206624_at NM_004654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004654.2 /DEF=Homo sapiens ubiquitin specific protease 9, Y chromosome (Drosophila fat facets related) (USP9Y), mRNA. /FEA=mRNA /GEN=USP9Y /PROD=Drosophila fat facets related, Y-linked /DB_XREF=gi:11641426 /UG=Hs.193145 ubiquitin specific protease 9, Y chromosome (Drosophila fat facets related) /FL=gb:NM_004654.2 gb:AF000986.2 NM_004654 ubiquitin specific peptidase 9, Y-linked USP9Y 8287 NM_004654 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0016579 // protein deubiquitination // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from sequence or structural similarity 206625_at NM_000322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000322.1 /DEF=Homo sapiens retinal degeneration, slow (retinitis pigmentosa 7) (RDS), mRNA. /FEA=mRNA /GEN=RDS /PROD=retinal degeneration, slow (retinitis pigmentosa7) /DB_XREF=gi:4506464 /UG=Hs.1937 retinal degeneration, slow (retinitis pigmentosa 7) /FL=gb:M73531.1 gb:NM_000322.1 NM_000322 peripherin 2 (retinal degeneration, slow) PRPH2 5961 NM_000322 /// XM_005249261 /// XR_427834 0007155 // cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206626_x_at BC001003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001003.2 /DEF=Homo sapiens, synovial sarcoma, X breakpoint 1, clone MGC:5162, mRNA, complete cds. /FEA=mRNA /PROD=synovial sarcoma, X breakpoint 1 /DB_XREF=gi:12803043 /UG=Hs.194759 synovial sarcoma, X breakpoint 1 /FL=gb:BC001003.2 gb:NM_005635.1 BC001003 synovial sarcoma, X breakpoint 1 SSX1 6756 NM_001278691 /// NM_005635 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement 206627_s_at NM_005635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005635.1 /DEF=Homo sapiens synovial sarcoma, X breakpoint 1 (SSX1), mRNA. /FEA=mRNA /GEN=SSX1 /PROD=synovial sarcoma, X breakpoint 1 /DB_XREF=gi:5032120 /UG=Hs.194759 synovial sarcoma, X breakpoint 1 /FL=gb:BC001003.2 gb:NM_005635.1 NM_005635 synovial sarcoma, X breakpoint 1 SSX1 6756 NM_001278691 /// NM_005635 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement 206628_at NM_000343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000343.1 /DEF=Homo sapiens solute carrier family 5 (sodiumglucose cotransporter), member 1 (SLC5A1), mRNA. /FEA=mRNA /GEN=SLC5A1 /PROD=solute carrier family 5 (sodiumglucosecotransporter), member 1 /DB_XREF=gi:4507030 /UG=Hs.1964 solute carrier family 5 (sodiumglucose cotransporter), member 1 /FL=gb:M24847.1 gb:NM_000343.1 NM_000343 solute carrier family 5 (sodium/glucose cotransporter), member 1 SLC5A1 6523 NM_000343 /// NM_001256314 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0005412 // glucose:sodium symporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation 206629_at NM_014694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014694.1 /DEF=Homo sapiens KIAA0605 gene product (KIAA0605), mRNA. /FEA=mRNA /GEN=KIAA0605 /PROD=KIAA0605 gene product /DB_XREF=gi:7662201 /UG=Hs.200594 KIAA0605 gene product /FL=gb:AB011177.1 gb:NM_014694.1 NM_014694 ADAMTS-like 2 ADAMTSL2 9719 NM_001145320 /// NM_014694 /// XM_005272237 /// XM_005272238 /// XM_005272239 /// XM_006717336 /// XM_006717337 0006508 // proteolysis // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 206630_at NM_000372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000372.1 /DEF=Homo sapiens tyrosinase (oculocutaneous albinism IA) (TYR), mRNA. /FEA=mRNA /GEN=TYR /PROD=tyrosinase (oculocutaneous albinism IA) /DB_XREF=gi:4507752 /UG=Hs.2053 tyrosinase (oculocutaneous albinism IA) /FL=gb:M27160.1 gb:M74314.1 gb:U01873.1 gb:NM_000372.1 NM_000372 tyrosinase TYR 7299 NM_000372 0006583 // melanin biosynthetic process from tyrosine // traceable author statement /// 0006726 // eye pigment biosynthetic process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004503 // monophenol monooxygenase activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 206631_at NM_000956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000956.1 /DEF=Homo sapiens prostaglandin E receptor 2 (subtype EP2), 53kD (PTGER2), mRNA. /FEA=mRNA /GEN=PTGER2 /PROD=prostaglandin E receptor 2 (subtype EP2), 53kD /DB_XREF=gi:4506254 /UG=Hs.2090 prostaglandin E receptor 2 (subtype EP2), 53kD /FL=gb:NM_000956.1 gb:U19487.1 NM_000956 prostaglandin E receptor 2 (subtype EP2), 53kDa PTGER2 5732 NM_000956 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // inferred from electronic annotation 206632_s_at NM_004900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004900.1 /DEF=Homo sapiens phorbolin (similar to apolipoprotein B mRNA editing protein) (DJ742C19.2), mRNA. /FEA=mRNA /GEN=DJ742C19.2 /PROD=phorbolin (similar to apolipoprotein B mRNAediting protein) /DB_XREF=gi:4758159 /UG=Hs.226307 phorbolin (similar to apolipoprotein B mRNA editing protein) /FL=gb:U61083.1 gb:NM_004900.1 NM_004900 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B APOBEC3B 9582 NM_001270411 /// NM_004900 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0009972 // cytidine deamination // inferred from direct assay /// 0009972 // cytidine deamination // inferred from mutant phenotype /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0044356 // clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from mutant phenotype /// 0071466 // cellular response to xenobiotic stimulus // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0004126 // cytidine deaminase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from mutant phenotype 206633_at NM_000079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000079.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) (CHRNA1), mRNA. /FEA=mRNA /GEN=CHRNA1 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 1 (muscle) precursor /DB_XREF=gi:4557456 /UG=Hs.2266 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) /FL=gb:NM_000079.1 NM_000079 cholinergic receptor, nicotinic, alpha 1 (muscle) CHRNA1 1134 NM_000079 /// NM_001039523 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from mutant phenotype /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from mutant phenotype /// 0007528 // neuromuscular junction development // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0048630 // skeletal muscle tissue growth // inferred from mutant phenotype /// 0050881 // musculoskeletal movement // inferred from mutant phenotype /// 0050905 // neuromuscular process // inferred from mutant phenotype /// 0070050 // neuron cellular homeostasis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // non-traceable author statement 0004889 // acetylcholine-activated cation-selective channel activity // inferred from mutant phenotype /// 0004889 // acetylcholine-activated cation-selective channel activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // traceable author statement /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from sequence or structural similarity /// 0042166 // acetylcholine binding // inferred from sequence or structural similarity 206634_at NM_005413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005413.1 /DEF=Homo sapiens sine oculis homeobox (Drosophila) homolog 3 (SIX3), mRNA. /FEA=mRNA /GEN=SIX3 /PROD=sine oculis homeobox (Drosophila) homolog 3 /DB_XREF=gi:4885596 /UG=Hs.227277 sine oculis homeobox (Drosophila) homolog 3 /FL=gb:NM_005413.1 NM_005413 SIX homeobox 3 SIX3 6496 NM_005413 0001654 // eye development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0021536 // diencephalon development // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021797 // forebrain anterior/posterior pattern specification // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048512 // circadian behavior // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206635_at NM_000748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000748.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) (CHRNB2), mRNA. /FEA=mRNA /GEN=CHRNB2 /PROD=cholinergic receptor, nicotinic, betapolypeptide 2 (neuronal) /DB_XREF=gi:4502832 /UG=Hs.2306 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) /FL=gb:U62437.1 gb:NM_000748.1 NM_000748 cholinergic receptor, nicotinic, beta 2 (neuronal) CHRNB2 1141 NM_000748 /// XM_006711143 0001508 // action potential // inferred from electronic annotation /// 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0007613 // memory // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from mutant phenotype /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0021562 // vestibulocochlear nerve development // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from sequence or structural similarity /// 0021771 // lateral geniculate nucleus development // inferred from sequence or structural similarity /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0032225 // regulation of synaptic transmission, dopaminergic // inferred from sequence or structural similarity /// 0032226 // positive regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0042053 // regulation of dopamine metabolic process // inferred from sequence or structural similarity /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042220 // response to cocaine // inferred from sequence or structural similarity /// 0042320 // regulation of circadian sleep/wake cycle, REM sleep // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0045188 // regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045759 // negative regulation of action potential // inferred from sequence or structural similarity /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0060084 // synaptic transmission involved in micturition // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator /// 0042166 // acetylcholine binding // inferred from mutant phenotype 206636_at NM_006506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006506.2 /DEF=Homo sapiens RAS p21 protein activator 2 (RASA2), mRNA. /FEA=mRNA /GEN=RASA2 /PROD=RAS p21 protein activator 2 /DB_XREF=gi:12545407 /UG=Hs.241548 RAS p21 protein activator 2 /FL=gb:D78155.1 gb:NM_006506.2 gb:D82880.1 gb:AF115573.1 NM_006506 RAS p21 protein activator 2 RASA2 5922 NM_006506 /// XM_005247688 /// XM_006713719 /// XM_006713720 0007165 // signal transduction // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206637_at NM_014879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014879.1 /DEF=Homo sapiens KIAA0001 gene product; putative G-protein-coupled receptor; G protein coupled receptor for UDP-glucose (KIAA0001), mRNA. /FEA=mRNA /GEN=KIAA0001 /PROD=KIAA0001 gene product; putativeG-protein-coupled receptor; G protein coupled receptor forUDP-glucose /DB_XREF=gi:7661847 /UG=Hs.2465 KIAA0001 gene product; putative G-protein-coupled receptor; G protein coupled receptor for UDP-glucose /FL=gb:D13626.1 gb:NM_014879.1 NM_014879 purinergic receptor P2Y, G-protein coupled, 14 P2RY14 9934 NM_001081455 /// NM_014879 /// XM_005247921 /// XM_005247922 /// XM_005247923 /// XM_006713832 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation /// 0045029 // UDP-activated nucleotide receptor activity // non-traceable author statement 206638_at NM_000867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000867.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), mRNA. /FEA=mRNA /GEN=HTR2B /PROD=5-hydroxytryptamine (serotonin) receptor 2B /DB_XREF=gi:4504538 /UG=Hs.2507 5-hydroxytryptamine (serotonin) receptor 2B /FL=gb:NM_000867.1 NM_000867 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled HTR2B 3357 NM_000867 /// XM_005246520 /// XM_006712482 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003300 // cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007507 // heart development // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0014033 // neural crest cell differentiation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014827 // intestine smooth muscle contraction // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from mutant phenotype /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0048598 // embryonic morphogenesis // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from mutant phenotype /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070371 // ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from mutant phenotype /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 0071502 // cellular response to temperature stimulus // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from mutant phenotype /// 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005099 // Ras GTPase activator activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from mutant phenotype /// 0008144 // drug binding // inferred from direct assay /// 0051378 // serotonin binding // inferred from direct assay 206639_x_at NM_002159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002159.1 /DEF=Homo sapiens histatin 1 (HTN1), mRNA. /FEA=mRNA /GEN=HTN1 /PROD=histatin 1 /DB_XREF=gi:4504528 /UG=Hs.250959 histatin 1 /FL=gb:M26664.1 gb:NM_002159.1 NM_002159 histatin 1 HTN1 3346 NM_002159 0031214 // biomineral tissue development // inferred from electronic annotation /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // non-traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 206640_x_at NM_001477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001477.1 /DEF=Homo sapiens G antigen 7B (GAGE7B), mRNA. /FEA=mRNA /GEN=GAGE7B /PROD=G antigen 7B /DB_XREF=gi:4503888 /UG=Hs.251677 G antigen 7B /FL=gb:AF055474.1 gb:NM_001477.1 NM_001477 G antigen 12B /// G antigen 12C /// G antigen 12D /// G antigen 12E /// G antigen 12F /// G antigen 12G /// G antigen 12H /// G antigen 12I /// G antigen 2A /// G antigen 2C /// G antigen 4 /// G antigen 5 /// G antigen 6 /// G antigen 7 GAGE12B /// GAGE12C /// GAGE12D /// GAGE12E /// GAGE12F /// GAGE12G /// GAGE12H /// GAGE12I /// GAGE2A /// GAGE2C /// GAGE4 /// GAGE5 /// GAGE6 /// GAGE7 2574 /// 2576 /// 2577 /// 2578 /// 2579 /// 26748 /// 645073 /// 729422 /// 729428 /// 729431 /// 729442 /// 729447 /// 100008586 /// 100132399 NM_001098405 /// NM_001098408 /// NM_001098409 /// NM_001098410 /// NM_001098418 /// NM_001127199 /// NM_001127212 /// NM_001127345 /// NM_001472 /// NM_001474 /// NM_001475 /// NM_001476 /// NM_001477 /// NM_021123 /// XM_005272739 /// XM_005278009 0006968 // cellular defense response // traceable author statement 0005515 // protein binding // inferred from physical interaction 206641_at NM_001192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001192.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), mRNA. /FEA=mRNA /GEN=TNFRSF17 /PROD=B-cell maturation factor /DB_XREF=gi:4507572 /UG=Hs.2556 tumor necrosis factor receptor superfamily, member 17 /FL=gb:NM_001192.1 NM_001192 tumor necrosis factor receptor superfamily, member 17 TNFRSF17 608 NM_001192 0002376 // immune system process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from reviewed computational analysis 0005886 // plasma membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // inferred from reviewed computational analysis 206642_at NM_001942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001942.1 /DEF=Homo sapiens desmoglein 1 (DSG1), mRNA. /FEA=mRNA /GEN=DSG1 /PROD=desmoglein 1 preproprotein /DB_XREF=gi:4503400 /UG=Hs.2633 desmoglein 1 /FL=gb:AF097935.1 gb:NM_001942.1 NM_001942 desmoglein 1 DSG1 1828 NM_001942 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007043 // cell-cell junction assembly // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement /// 0032570 // response to progesterone // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0015643 // toxic substance binding // non-traceable author statement /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206643_at NM_002108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002108.2 /DEF=Homo sapiens histidine ammonia-lyase (HAL), mRNA. /FEA=mRNA /GEN=HAL /PROD=histidine ammonia-lyase /DB_XREF=gi:4809282 /UG=Hs.263435 histidine ammonia-lyase /FL=gb:D16626.1 gb:NM_002108.2 NM_002108 histidine ammonia-lyase HAL 3034 NM_001258333 /// NM_001258334 /// NM_002108 /// XM_005268821 0006547 // histidine metabolic process // inferred from electronic annotation /// 0006548 // histidine catabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019556 // histidine catabolic process to glutamate and formamide // inferred from electronic annotation /// 0019557 // histidine catabolic process to glutamate and formate // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004397 // histidine ammonia-lyase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016841 // ammonia-lyase activity // inferred from electronic annotation 206644_at NM_000475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000475.2 /DEF=Homo sapiens nuclear receptor subfamily 0, group B, member 1 (NR0B1), mRNA. /FEA=mRNA /GEN=NR0B1 /PROD=adrenal hypoplasia protein /DB_XREF=gi:5016089 /UG=Hs.268490 nuclear receptor subfamily 0, group B, member 1 /FL=gb:NM_000475.2 NM_000475 nuclear receptor subfamily 0, group B, member 1 NR0B1 190 NM_000475 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007530 // sex determination // inferred from electronic annotation /// 0008104 // protein localization // inferred from direct assay /// 0008406 // gonad development // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0021854 // hypothalamus development // non-traceable author statement /// 0021983 // pituitary gland development // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // non-traceable author statement /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060008 // Sertoli cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032448 // DNA hairpin binding // inferred from direct assay /// 0035258 // steroid hormone receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0050682 // AF-2 domain binding // inferred from physical interaction 206645_s_at NM_000475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000475.2 /DEF=Homo sapiens nuclear receptor subfamily 0, group B, member 1 (NR0B1), mRNA. /FEA=mRNA /GEN=NR0B1 /PROD=adrenal hypoplasia protein /DB_XREF=gi:5016089 /UG=Hs.268490 nuclear receptor subfamily 0, group B, member 1 /FL=gb:NM_000475.2 NM_000475 nuclear receptor subfamily 0, group B, member 1 NR0B1 190 NM_000475 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007530 // sex determination // inferred from electronic annotation /// 0008104 // protein localization // inferred from direct assay /// 0008406 // gonad development // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0021854 // hypothalamus development // non-traceable author statement /// 0021983 // pituitary gland development // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // non-traceable author statement /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060008 // Sertoli cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032448 // DNA hairpin binding // inferred from direct assay /// 0035258 // steroid hormone receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0050682 // AF-2 domain binding // inferred from physical interaction 206646_at NM_005269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005269.1 /DEF=Homo sapiens glioma-associated oncogene homolog (zinc finger protein) (GLI), mRNA. /FEA=mRNA /GEN=GLI /PROD=glioma-associated oncogene homolog /DB_XREF=gi:4885278 /UG=Hs.2693 glioma-associated oncogene homolog (zinc finger protein) /FL=gb:NM_005269.1 NM_005269 GLI family zinc finger 1 GLI1 2735 NM_001160045 /// NM_001167609 /// NM_005269 /// XM_005268799 0001649 // osteoblast differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from direct assay /// 0007224 // smoothened signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007418 // ventral midline development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008589 // regulation of smoothened signaling pathway // traceable author statement /// 0009913 // epidermal cell differentiation // inferred from direct assay /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from electronic annotation /// 0021938 // smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045880 // positive regulation of smoothened signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048546 // digestive tract morphogenesis // traceable author statement /// 0060032 // notochord regression // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0072372 // primary cilium // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206647_at NM_005332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005332.2 /DEF=Homo sapiens hemoglobin, zeta (HBZ), mRNA. /FEA=mRNA /GEN=HBZ /PROD=hemoglobin, zeta /DB_XREF=gi:6633805 /UG=Hs.272003 hemoglobin, zeta /FL=gb:M24173.1 gb:NM_005332.2 NM_005332 hemoglobin, zeta HBZ 3050 NM_005332 /// XM_005255287 /// XM_005255288 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015671 // oxygen transport // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation 0005833 // hemoglobin complex // inferred from electronic annotation 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206648_at NM_016536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016536.1 /DEF=Homo sapiens HSPC059 protein (HSPC059), mRNA. /FEA=mRNA /GEN=HSPC059 /PROD=HSPC059 protein /DB_XREF=gi:8923786 /UG=Hs.272384 HSPC059 protein /FL=gb:AF161544.2 gb:NM_016536.1 NM_016536 zinc finger protein 571 ZNF571 51276 NM_001290314 /// NM_016536 /// XM_005258977 /// XM_005258979 /// XM_006723239 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0019058 // viral life cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0019028 // viral capsid // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206649_s_at NM_006521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006521.2 /DEF=Homo sapiens transcription factor binding to IGHM enhancer 3 (TFE3), mRNA. /FEA=mRNA /GEN=TFE3 /PROD=transcription factor binding to IGHM enhancer 3 /DB_XREF=gi:8659573 /UG=Hs.274184 transcription factor binding to IGHM enhancer 3 /FL=gb:NM_006521.2 NM_006521 transcription factor binding to IGHM enhancer 3 TFE3 7030 NM_001282142 /// NM_006521 /// XM_006724549 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 206650_at NM_018134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018134.1 /DEF=Homo sapiens hypothetical protein FLJ10547 (FLJ10547), mRNA. /FEA=mRNA /GEN=FLJ10547 /PROD=hypothetical protein FLJ10547 /DB_XREF=gi:8922508 /UG=Hs.274356 hypothetical protein FLJ10547 /FL=gb:NM_018134.1 NM_018134 IQ motif containing C IQCC 55721 NM_001160042 /// NM_018134 0005515 // protein binding // inferred from electronic annotation 206651_s_at NM_016413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016413.1 /DEF=Homo sapiens carboxypeptidase B-like protein (LOC51745), mRNA. /FEA=mRNA /GEN=LOC51745 /PROD=carboxypeptidase B-like protein /DB_XREF=gi:7706530 /UG=Hs.274495 carboxypeptidase B-like protein /FL=gb:AB011969.1 gb:NM_016413.1 NM_016413 carboxypeptidase B2 (plasma) CPB2 1361 NM_001278541 /// NM_001872 /// NM_016413 /// XM_005266257 /// XM_005266258 /// XM_005266259 0003331 // positive regulation of extracellular matrix constituent secretion // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0010757 // negative regulation of plasminogen activation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0097421 // liver regeneration // inferred from electronic annotation /// 2000346 // negative regulation of hepatocyte proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206652_at NM_016384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016384.1 /DEF=Homo sapiens hypothetical protein (HSPC050), mRNA. /FEA=mRNA /GEN=HSPC050 /PROD=hypothetical protein /DB_XREF=gi:7705438 /UG=Hs.278985 hypothetical protein /FL=gb:AF161535.1 gb:NM_016384.1 NM_016384 zinc finger, MYM-type 5 ZMYM5 9205 NM_001039649 /// NM_001039650 /// NM_001142684 /// NM_014242 /// XM_005266593 /// XM_005266594 /// XM_005266595 /// XM_006719894 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206653_at BF062139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062139 /FEA=EST /DB_XREF=gi:10821049 /DB_XREF=est:7k72f10.x1 /CLONE=IMAGE:3481099 /UG=Hs.282387 polymerase (RNA) III (DNA directed) (32kD) /FL=gb:U93868.1 gb:NM_006467.1 BF062139 polymerase (RNA) III (DNA directed) polypeptide G (32kD) POLR3G 10622 NM_006467 /// XM_005248404 /// XM_006714519 /// XM_006714520 0002376 // immune system process // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // not recorded /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008283 // cell proliferation // not recorded /// 0008283 // cell proliferation // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement 206654_s_at NM_006467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006467.1 /DEF=Homo sapiens polymerase (RNA) III (DNA directed) (32kD) (RPC32), mRNA. /FEA=mRNA /GEN=RPC32 /PROD=polymerase (RNA) III (DNA directed) (32kD) /DB_XREF=gi:5454017 /UG=Hs.282387 polymerase (RNA) III (DNA directed) (32kD) /FL=gb:U93868.1 gb:NM_006467.1 NM_006467 polymerase (RNA) III (DNA directed) polypeptide G (32kD) POLR3G 10622 NM_006467 /// XM_005248404 /// XM_006714519 /// XM_006714520 0002376 // immune system process // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // not recorded /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008283 // cell proliferation // not recorded /// 0008283 // cell proliferation // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement 206655_s_at NM_000407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000407.3 /DEF=Homo sapiens glycoprotein Ib (platelet), beta polypeptide (GP1BB), mRNA. /FEA=mRNA /GEN=GP1BB /PROD=glycoprotein Ib beta polypeptide precursor /DB_XREF=gi:9945387 /UG=Hs.283743 glycoprotein Ib (platelet), beta polypeptide /FL=gb:J03259.1 gb:NM_000407.3 NM_000407 glycoprotein Ib (platelet), beta polypeptide /// septin 5 /// SEPT5-GP1BB readthrough GP1BB /// SEPT5 /// SEPT5-GP1BB 2812 /// 5413 /// 100526833 NM_000407 /// NM_001009939 /// NM_002688 /// NR_037611 /// NR_037612 0000910 // cytokinesis // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // traceable author statement /// 0017157 // regulation of exocytosis // inferred from mutant phenotype /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 206656_s_at BC000353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000353.1 /DEF=Homo sapiens, myogenic factor 3, clone MGC:8630, mRNA, complete cds. /FEA=mRNA /PROD=myogenic factor 3 /DB_XREF=gi:12653170 /UG=Hs.284203 myogenic factor 3 /FL=gb:BC000353.1 gb:NM_002478.2 BC000353 adipocyte plasma membrane associated protein APMAP 57136 NM_020531 /// XM_005260763 0009058 // biosynthetic process // inferred from electronic annotation 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004064 // arylesterase activity // inferred from direct assay /// 0016844 // strictosidine synthase activity // inferred from electronic annotation 206657_s_at NM_002478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002478.2 /DEF=Homo sapiens myogenic factor 3 (MYOD1), mRNA. /FEA=mRNA /GEN=MYOD1 /PROD=myogenic factor 3 /DB_XREF=gi:6006026 /UG=Hs.284203 myogenic factor 3 /FL=gb:BC000353.1 gb:NM_002478.2 NM_002478 myogenic differentiation 1 MYOD1 4654 NM_002478 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007518 // myoblast fate determination // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0014904 // myotube cell development // inferred from direct assay /// 0014908 // myotube differentiation involved in skeletal muscle regeneration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043415 // positive regulation of skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043503 // skeletal muscle fiber adaptation // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from sequence or structural similarity /// 0043967 // histone H4 acetylation // inferred from sequence or structural similarity /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 1901741 // positive regulation of myoblast fusion // inferred from direct assay 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 206658_at NM_030570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030570.1 /DEF=Homo sapiens hypothetical protein MGC10902 (MGC10902), mRNA. /FEA=mRNA /GEN=MGC10902 /PROD=hypothetical protein MGC10902 /DB_XREF=gi:13399329 /UG=Hs.284211 hypothetical protein MGC10902 /FL=gb:BC004304.1 gb:NM_030570.1 NM_030570 uroplakin 3B UPK3B 80761 NM_030570 /// NM_182683 /// NM_182684 /// XM_005250612 /// XM_005250613 /// XM_005250614 /// XM_006716140 /// XM_006716141 /// XM_006716142 0010629 // negative regulation of gene expression // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 206659_at NM_025024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025024.1 /DEF=Homo sapiens hypothetical protein FLJ14082 (FLJ14082), mRNA. /FEA=mRNA /GEN=FLJ14082 /PROD=hypothetical protein FLJ14082 /DB_XREF=gi:13376542 /UG=Hs.287622 hypothetical protein FLJ14082 /FL=gb:NM_025024.1 NM_025024 /// Homo sapiens cDNA FLJ31405 fis, clone NT2NE2000064. AC009237.8 /// AK055967 206660_at NM_020070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020070.1 /DEF=Homo sapiens immunoglobulin lambda-like polypeptide 1 (IGLL1), mRNA. /FEA=mRNA /GEN=IGLL1 /PROD=immunoglobulin lambda-like polypeptide 1 /DB_XREF=gi:13399297 /UG=Hs.288168 immunoglobulin lambda-like polypeptide 1 /FL=gb:NM_020070.1 gb:M27749.1 NM_020070 immunoglobulin lambda-like polypeptide 1 IGLL1 3543 NM_020070 /// NM_152855 0006955 // immune response // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 206661_at NM_025104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025104.1 /DEF=Homo sapiens hypothetical protein FLJ13087 (FLJ13087), mRNA. /FEA=mRNA /GEN=FLJ13087 /PROD=hypothetical protein FLJ13087 /DB_XREF=gi:13376670 /UG=Hs.288623 hypothetical protein FLJ13087 /FL=gb:NM_025104.1 NM_025104 DBF4 zinc finger B DBF4B 80174 NM_025104 /// NM_145663 /// NR_036623 /// XM_006722098 /// XM_006722099 /// XM_006722100 /// XM_006722101 /// XM_006722102 /// XM_006722103 /// XM_006722104 /// XM_006722105 /// XM_006722106 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206662_at NM_002064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002064.1 /DEF=Homo sapiens glutaredoxin (thioltransferase) (GLRX), mRNA. /FEA=mRNA /GEN=GLRX /PROD=glutaredoxin (thioltransferase) /DB_XREF=gi:4504024 /UG=Hs.28988 glutaredoxin (thioltransferase) /FL=gb:AF069668.1 gb:NM_002064.1 NM_002064 glutaredoxin (thioltransferase) GLRX 2745 NM_001118890 /// NM_001243658 /// NM_001243659 /// NM_002064 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015038 // glutathione disulfide oxidoreductase activity // traceable author statement /// 0047485 // protein N-terminus binding // inferred from physical interaction 206663_at NM_003112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003112.1 /DEF=Homo sapiens Sp4 transcription factor (SP4), mRNA. /FEA=mRNA /GEN=SP4 /PROD=Sp4 transcription factor /DB_XREF=gi:4507168 /UG=Hs.2982 Sp4 transcription factor /FL=gb:NM_003112.1 NM_003112 Sp4 transcription factor SP4 6671 NM_003112 /// XM_005249828 /// XM_005249829 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0008016 // regulation of heart contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206664_at NM_001041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001041.1 /DEF=Homo sapiens sucrase-isomaltase (SI), mRNA. /FEA=mRNA /GEN=SI /PROD=sucrase-isomaltase /DB_XREF=gi:4506944 /UG=Hs.2996 sucrase-isomaltase /FL=gb:NM_001041.1 NM_001041 sucrase-isomaltase (alpha-glucosidase) SI 6476 NM_001041 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044245 // polysaccharide digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004558 // alpha-glucosidase activity // traceable author statement /// 0004574 // oligo-1,6-glucosidase activity // inferred from electronic annotation /// 0004575 // sucrose alpha-glucosidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 206665_s_at NM_001191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001191.1 /DEF=Homo sapiens BCL2-like 1 (BCL2L1), mRNA. /FEA=mRNA /GEN=BCL2L1 /PROD=BCL2-like 1 /DB_XREF=gi:4502380 /UG=Hs.305890 BCL2-like 1 /FL=gb:NM_001191.1 NM_001191 BCL2-like 1 BCL2L1 598 NM_001191 /// NM_138578 /// XM_005260481 /// XM_005260482 /// XM_005260483 /// XM_005260484 /// XM_005260485 /// XM_005260486 /// XM_005260487 /// XM_006723843 /// XM_006723844 /// XM_006723845 0000910 // cytokinesis // inferred from mutant phenotype /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0019050 // suppression by virus of host apoptotic process // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046898 // response to cycloheximide // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071839 // apoptotic process in bone marrow // inferred from electronic annotation /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred by curator /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // non-traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded /// 0051434 // BH3 domain binding // inferred from physical interaction 206666_at NM_002104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002104.1 /DEF=Homo sapiens granzyme K (serine protease, granzyme 3; tryptase II) (GZMK), mRNA. /FEA=mRNA /GEN=GZMK /PROD=granzyme K precursor /DB_XREF=gi:4504234 /UG=Hs.3066 granzyme K (serine protease, granzyme 3; tryptase II) /FL=gb:U35237.1 gb:NM_002104.1 gb:U26174.1 NM_002104 granzyme K (granzyme 3; tryptase II) GZMK 3003 NM_002104 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 206667_s_at AF005037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005037.1 /DEF=Homo sapiens secretory carrier membrane protein (SCAMP1) mRNA, complete cds. /FEA=mRNA /GEN=SCAMP1 /PROD=secretory carrier membrane protein /DB_XREF=gi:2232238 /UG=Hs.31218 secretory carrier membrane protein 1 /FL=gb:AF005037.1 gb:AF038966.1 gb:NM_004866.1 AF005037 secretory carrier membrane protein 1 SCAMP1 9522 NM_001290229 /// NM_004866 /// NM_052822 /// NR_110885 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 206668_s_at NM_004866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004866.1 /DEF=Homo sapiens secretory carrier membrane protein 1 (SCAMP1), mRNA. /FEA=mRNA /GEN=SCAMP1 /PROD=secretory carrier membrane protein 1 /DB_XREF=gi:4759063 /UG=Hs.31218 secretory carrier membrane protein 1 /FL=gb:AF005037.1 gb:AF038966.1 gb:NM_004866.1 NM_004866 secretory carrier membrane protein 1 SCAMP1 9522 NM_001290229 /// NM_004866 /// NM_052822 /// NR_110885 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 206669_at NM_013445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013445.1 /DEF=Homo sapiens glutamate decarboxylase 1 (brain, 67kD) (GAD1), transcript variant GAD25, mRNA. /FEA=mRNA /GEN=GAD1 /PROD=glutamate decarboxylase 1, isoform GAD25 /DB_XREF=gi:7305076 /UG=Hs.324784 glutamate decarboxylase 1 (brain, 67kD) /FL=gb:BC002815.1 gb:AF178853.1 gb:NM_013445.1 NM_013445 glutamate decarboxylase 1 (brain, 67kDa) GAD1 2571 NM_000817 /// NM_013445 /// XM_005246443 /// XM_005246444 0006538 // glutamate catabolic process // traceable author statement /// 0006540 // glutamate decarboxylation to succinate // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009449 // gamma-aminobutyric acid biosynthetic process // inferred from electronic annotation /// 0018352 // protein-pyridoxal-5-phosphate linkage // traceable author statement /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0012506 // vesicle membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 206670_s_at NM_013445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013445.1 /DEF=Homo sapiens glutamate decarboxylase 1 (brain, 67kD) (GAD1), transcript variant GAD25, mRNA. /FEA=mRNA /GEN=GAD1 /PROD=glutamate decarboxylase 1, isoform GAD25 /DB_XREF=gi:7305076 /UG=Hs.324784 glutamate decarboxylase 1 (brain, 67kD) /FL=gb:BC002815.1 gb:AF178853.1 gb:NM_013445.1 NM_013445 glutamate decarboxylase 1 (brain, 67kDa) GAD1 2571 NM_000817 /// NM_013445 /// XM_005246443 /// XM_005246444 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006540 // glutamate decarboxylation to succinate // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009449 // gamma-aminobutyric acid biosynthetic process // inferred from electronic annotation /// 0018352 // protein-pyridoxal-5-phosphate linkage // traceable author statement /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0012506 // vesicle membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 206671_at NM_000541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000541.2 /DEF=Homo sapiens S-antigen; retina and pineal gland (arrestin) (SAG), mRNA. /FEA=mRNA /GEN=SAG /PROD=S-arrestin /DB_XREF=gi:10880124 /UG=Hs.32721 S-antigen; retina and pineal gland (arrestin) /FL=gb:NM_000541.2 NM_000541 S-antigen; retina and pineal gland (arrestin) SAG 6295 NM_000541 /// XM_005246099 /// XM_005246100 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0002046 // opsin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0051219 // phosphoprotein binding // inferred from electronic annotation 206672_at NM_000486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000486.2 /DEF=Homo sapiens aquaporin 2 (collecting duct) (AQP2), mRNA. /FEA=mRNA /GEN=AQP2 /PROD=aquaporin 2 /DB_XREF=gi:4755122 /UG=Hs.37025 aquaporin 2 (collecting duct) /FL=gb:NM_000486.2 NM_000486 aquaporin 2 (collecting duct) AQP2 359 NM_000486 0003097 // renal water transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0009414 // response to water deprivation // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0015793 // glycerol transport // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071288 // cellular response to mercury ion // inferred from direct assay /// 0072205 // metanephric collecting duct development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0015168 // glycerol transmembrane transporter activity // inferred from direct assay /// 0015250 // water channel activity // not recorded /// 0030165 // PDZ domain binding // inferred from electronic annotation 206673_at NM_007223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007223.1 /DEF=Homo sapiens putative G protein coupled receptor (GPR), mRNA. /FEA=mRNA /GEN=GPR /PROD=putative G protein coupled receptor /DB_XREF=gi:6005771 /UG=Hs.37196 putative G protein coupled receptor /FL=gb:D38449.1 gb:NM_007223.1 NM_007223 G protein-coupled receptor 176 GPR176 11245 NM_001271854 /// NM_001271855 /// NM_007223 /// XM_005254139 /// XM_006720379 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 206674_at NM_004119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004119.1 /DEF=Homo sapiens fms-related tyrosine kinase 3 (FLT3), mRNA. /FEA=mRNA /GEN=FLT3 /PROD=fms-related tyrosine kinase 3 /DB_XREF=gi:4758395 /UG=Hs.385 fms-related tyrosine kinase 3 /FL=gb:U02687.1 gb:NM_004119.1 NM_004119 fms-related tyrosine kinase 3 FLT3 2322 NM_004119 0001776 // leukocyte homeostasis // inferred from sequence or structural similarity /// 0002318 // myeloid progenitor cell differentiation // inferred from sequence or structural similarity /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0002572 // pro-T cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0035726 // common myeloid progenitor cell proliferation // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // traceable author statement /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043410 // positive regulation of MAPK cascade // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0046651 // lymphocyte proliferation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // traceable author statement /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // traceable author statement /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from sequence or structural similarity /// 0005021 // vascular endothelial growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation 206675_s_at NM_005414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005414.1 /DEF=Homo sapiens SKI-like (SKIL), mRNA. /FEA=mRNA /GEN=SKIL /PROD=SKI-like /DB_XREF=gi:4885598 /UG=Hs.38783 SKI-like /FL=gb:NM_005414.1 NM_005414 SKI-like proto-oncogene SKIL 6498 NM_001145097 /// NM_001145098 /// NM_001248008 /// NM_005414 /// XM_005247721 /// XM_006713735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0046677 // response to antibiotic // inferred from expression pattern /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from mutant phenotype /// 0070207 // protein homotrimerization // inferred from direct assay /// 0070208 // protein heterotrimerization // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction 206676_at M33326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33326.1 /DEF=Human nonspecific cross-reacting antigen (NCA) mRNA, complete cds. /FEA=mRNA /GEN=NCA /PROD=non-specific cross reacting antigen /DB_XREF=gi:189101 /UG=Hs.41 carcinoembryonic antigen-related cell adhesion molecule 8 /FL=gb:M33326.1 gb:NM_001816.1 M33326 carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 1088 NM_001816 /// XM_005258432 /// XM_005258433 0006955 // immune response // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206677_at NM_002277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002277.1 /DEF=Homo sapiens keratin, hair, acidic,1 (KRTHA1), mRNA. /FEA=mRNA /GEN=KRTHA1 /PROD=type I hair keratin 1 /DB_XREF=gi:4504920 /UG=Hs.41696 keratin, hair, acidic,1 /FL=gb:NM_002277.1 NM_002277 keratin 31 KRT31 3881 NM_002277 /// XM_005257351 /// XM_005276944 0008544 // epidermis development // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 206678_at NM_000806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000806.2 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), mRNA. /FEA=mRNA /GEN=GABRA1 /PROD=gamma-aminobutyric acid (GABA) A receptor, alpha1 precursor /DB_XREF=gi:4585862 /UG=Hs.45740 gamma-aminobutyric acid (GABA) A receptor, alpha 1 /FL=gb:NM_000806.2 NM_000806 gamma-aminobutyric acid (GABA) A receptor, alpha 1 GABRA1 2554 NM_000806 /// NM_001127643 /// NM_001127644 /// NM_001127645 /// NM_001127646 /// NM_001127647 /// NM_001127648 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0051932 // synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from sequence or structural similarity /// 0016917 // GABA receptor activity // inferred from sequence or structural similarity 206679_at NM_001163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001163.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) (APBA1), mRNA. /FEA=mRNA /GEN=APBA1 /PROD=amyloid beta (A4) precursor protein-binding,family A, member 1 (X11) /DB_XREF=gi:4502128 /UG=Hs.4880 amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) /FL=gb:AF029106.1 gb:AF047347.1 gb:NM_001163.1 NM_001163 amyloid beta (A4) precursor protein-binding, family A, member 1 APBA1 320 NM_001163 /// XM_005251967 /// XM_005251968 /// XM_006717093 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 206680_at NM_005894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005894.1 /DEF=Homo sapiens CD5 antigen-like (scavenger receptor cysteine rich family) (CD5L), mRNA. /FEA=mRNA /GEN=CD5L /PROD=CD5 antigen-like (scavenger receptor cysteinerich family) /DB_XREF=gi:5174410 /UG=Hs.52002 CD5 antigen-like (scavenger receptor cysteine rich family) /FL=gb:U82812.1 gb:AF011429.1 gb:NM_005894.1 NM_005894 CD5 molecule-like CD5L 922 NM_005894 /// XM_005245602 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005044 // scavenger receptor activity // inferred from electronic annotation 206681_x_at NM_001502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001502.1 /DEF=Homo sapiens glycoprotein 2 (zymogen granule membrane) (GP2), mRNA. /FEA=mRNA /GEN=GP2 /PROD=glycoprotein 2 (zymogen granule membrane) /DB_XREF=gi:4504074 /UG=Hs.53985 glycoprotein 2 (zymogen granule membrane) /FL=gb:U36221.1 gb:NM_001502.1 NM_001502 glycoprotein 2 (zymogen granule membrane) GP2 2813 NM_001007240 /// NM_001007241 /// NM_001007242 /// NM_001502 /// XM_005255259 /// XM_005255261 /// XR_429676 0002412 // antigen transcytosis by M cells in mucosal-associated lymphoid tissue // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003823 // antigen binding // inferred from electronic annotation 206682_at NM_006344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006344.1 /DEF=Homo sapiens macrophage lectin 2 (calcium dependent) (HML2), mRNA. /FEA=mRNA /GEN=HML2 /PROD=macrophage lectin 2 (calcium dependent) /DB_XREF=gi:5453683 /UG=Hs.54403 macrophage lectin 2 (calcium dependent) /FL=gb:D50532.1 gb:NM_006344.1 NM_006344 C-type lectin domain family 10, member A CLEC10A 10462 NM_006344 /// NM_182906 /// XM_005256411 /// XM_005256412 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030246 // carbohydrate binding // inferred from electronic annotation 206683_at NM_003447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003447.1 /DEF=Homo sapiens zinc finger protein 165 (ZNF165), mRNA. /FEA=mRNA /GEN=ZNF165 /PROD=zinc finger protein 165 /DB_XREF=gi:4508000 /UG=Hs.55481 zinc finger protein 165 /FL=gb:U78722.1 gb:NM_003447.1 NM_003447 zinc finger protein 165 ZNF165 7718 NM_003447 /// XM_005249371 /// XM_005249372 /// XM_005249373 /// XM_006715179 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206684_s_at NM_006856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006856.1 /DEF=Homo sapiens activating transcription factor 7 (ATF7), mRNA. /FEA=mRNA /GEN=ATF7 /PROD=activating transcription factor 7 /DB_XREF=gi:5802979 /UG=Hs.55888 activating transcription factor 7 /FL=gb:NM_006856.1 NM_006856 activating transcription factor 7 ATF7 11016 NM_001130059 /// NM_001130060 /// NM_001206682 /// NM_001206683 /// NM_006856 /// NR_073163 /// XM_005268587 /// XM_006719202 /// XM_006719203 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0034399 // nuclear periphery // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay 206685_at NM_018985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018985.1 /DEF=Homo sapiens hypothetical protein (HCGIV.9), mRNA. /FEA=mRNA /GEN=HCGIV.9 /PROD=hypothetical protein /DB_XREF=gi:9506770 /UG=Hs.60856 hypothetical protein /FL=gb:NM_018985.1 NM_018985 HLA complex group 4 (non-protein coding) HCG4 54435 NR_002139 206686_at NM_002610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002610.2 /DEF=Homo sapiens pyruvate dehydrogenase kinase, isoenzyme 1 (PDK1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PDK1 /PROD=pyruvate dehydrogenase kinase, isoenzyme 1 /DB_XREF=gi:7108358 /UG=Hs.61712 pyruvate dehydrogenase kinase, isoenzyme 1 /FL=gb:L42450.1 gb:NM_002610.2 NM_002610 pyruvate dehydrogenase kinase, isozyme 1 PDK1 5163 NM_001278549 /// NM_002610 /// NR_103729 /// NR_103731 /// XM_006712594 /// XM_006712595 /// XR_427093 /// XR_427094 /// XR_427095 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097411 // hypoxia-inducible factor-1alpha signaling pathway // inferred from mutant phenotype 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206687_s_at NM_002831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002831.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), mRNA. /FEA=mRNA /GEN=PTPN6 /PROD=protein tyrosine phosphatase, non-receptor type6 /DB_XREF=gi:4506296 /UG=Hs.63489 protein tyrosine phosphatase, non-receptor type 6 /FL=gb:M74903.1 gb:M77273.1 gb:NM_002831.1 NM_002831 protein tyrosine phosphatase, non-receptor type 6 PTPN6 5777 NM_002831 /// NM_080548 /// NM_080549 /// XM_006718994 0002924 // negative regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045577 // regulation of B cell differentiation // inferred from electronic annotation /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0042105 // alpha-beta T cell receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from electronic annotation 206688_s_at NM_006693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006693.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 4, 30kD subunit (CPSF4), mRNA. /FEA=mRNA /GEN=CPSF4 /PROD=cleavage and polyadenylation specific factor 4,30kD subunit /DB_XREF=gi:5729938 /UG=Hs.6351 cleavage and polyadenylation specific factor 4, 30kD subunit /FL=gb:U79569.1 gb:NM_006693.1 NM_006693 cleavage and polyadenylation specific factor 4, 30kDa CPSF4 10898 NM_001081559 /// NM_006693 0006397 // mRNA processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0046778 // modification by virus of host mRNA processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206689_x_at NM_006388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006388.1 /DEF=Homo sapiens HIV-1 Tat interactive protein, 60 kDa (HTATIP), mRNA. /FEA=mRNA /GEN=HTATIP /PROD=HIV-1 Tat interactive protein, 60 kDa /DB_XREF=gi:5454127 /UG=Hs.6364 HIV-1 Tat interactive protein, 60 kDa /FL=gb:U40989.1 gb:U74667.1 gb:NM_006388.1 NM_006388 K(lysine) acetyltransferase 5 KAT5 10524 NM_001206833 /// NM_006388 /// NM_182709 /// NM_182710 /// XM_006718421 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction 206690_at NM_001094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001094.2 /DEF=Homo sapiens amiloride-sensitive cation channel 1, neuronal (degenerin) (ACCN1), mRNA. /FEA=mRNA /GEN=ACCN1 /PROD=neuronal amiloride-sensitive cation channel 1 /DB_XREF=gi:9998943 /UG=Hs.6517 amiloride-sensitive cation channel 1, neuronal (degenerin) /FL=gb:U50352.1 gb:U57352.1 gb:NM_001094.2 NM_001094 acid-sensing (proton-gated) ion channel 2 ASIC2 40 NM_001094 /// NM_183377 0001101 // response to acid // inferred from electronic annotation /// 0003026 // regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0015672 // monovalent inorganic cation transport // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0050915 // sensory perception of sour taste // inferred from mutant phenotype /// 0050974 // detection of mechanical stimulus involved in sensory perception // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from electronic annotation /// 0022839 // ion gated channel activity // inferred from electronic annotation 206691_s_at NM_006849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006849.1 /DEF=Homo sapiens protein disulfide isomerase (PDI), mRNA. /FEA=mRNA /GEN=PDI /PROD=protein disulfide isomerase /DB_XREF=gi:5803118 /UG=Hs.66581 protein disulfide isomerase /FL=gb:U19948.1 gb:NM_006849.1 NM_006849 protein disulfide isomerase family A, member 2 PDIA2 64714 NM_006849 0006457 // protein folding // not recorded /// 0006621 // protein retention in ER lumen // traceable author statement /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // not recorded /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement 0003756 // protein disulfide isomerase activity // not recorded /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005094 // Rho GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // not recorded 206692_at NM_002241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002241.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), mRNA. /FEA=mRNA /GEN=KCNJ10 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 10 /DB_XREF=gi:4504832 /UG=Hs.66727 potassium inwardly-rectifying channel, subfamily J, member 10 /FL=gb:U52155.1 gb:NM_002241.1 NM_002241 potassium inwardly-rectifying channel, subfamily J, member 10 KCNJ10 3766 NM_002241 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0009637 // response to blue light // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0021554 // optic nerve development // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051935 // L-glutamate uptake involved in synaptic transmission // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055075 // potassium ion homeostasis // inferred from electronic annotation /// 0060075 // regulation of resting membrane potential // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015272 // ATP-activated inward rectifier potassium channel activity // traceable author statement /// 0042802 // identical protein binding // inferred from electronic annotation 206693_at NM_000880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000880.1 /DEF=Homo sapiens interleukin 7 (IL7), mRNA. /FEA=mRNA /GEN=IL7 /PROD=interleukin 7 /DB_XREF=gi:4504676 /UG=Hs.72927 interleukin 7 /FL=gb:J04156.1 gb:NM_000880.1 NM_000880 interleukin 7 IL7 3574 NM_000880 /// NM_001199886 /// NM_001199887 /// NM_001199888 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005139 // interleukin-7 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from sequence or structural similarity 206694_at NM_006229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006229.1 /DEF=Homo sapiens pancreatic lipase-related protein 1 (PNLIPRP1), mRNA. /FEA=mRNA /GEN=PNLIPRP1 /PROD=pancreatic lipase-related protein 1 /DB_XREF=gi:5453919 /UG=Hs.73923 pancreatic lipase-related protein 1 /FL=gb:M93283.1 gb:NM_006229.1 NM_006229 pancreatic lipase-related protein 1 PNLIPRP1 5407 NM_006229 /// XM_005269903 0006629 // lipid metabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016298 // lipase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206695_x_at NM_003423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003423.1 /DEF=Homo sapiens zinc finger protein 43 (HTF6) (ZNF43), mRNA. /FEA=mRNA /GEN=ZNF43 /PROD=zinc finger protein 43 (HTF6) /DB_XREF=gi:4508026 /UG=Hs.74107 zinc finger protein 43 (HTF6) /FL=gb:NM_003423.1 NM_003423 zinc finger protein 43 ZNF43 7594 NM_001256648 /// NM_001256649 /// NM_001256650 /// NM_001256651 /// NM_001256653 /// NM_001256654 /// NM_003423 /// XM_005260057 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 206696_at NM_000273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000273.1 /DEF=Homo sapiens ocular albinism 1 (Nettleship-Falls) (OA1), mRNA. /FEA=mRNA /GEN=OA1 /PROD=ocular albinism 1 (Nettleship-Falls) protein /DB_XREF=gi:4557806 /UG=Hs.74124 ocular albinism 1 (Nettleship-Falls) /FL=gb:NM_000273.1 NM_000273 G protein-coupled receptor 143 GPR143 4935 NM_000273 /// XM_005274541 /// XM_005274542 0006726 // eye pigment biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0032400 // melanosome localization // inferred from direct assay /// 0032400 // melanosome localization // inferred from sequence or structural similarity /// 0032402 // melanosome transport // inferred from direct assay /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0050848 // regulation of calcium-mediated signaling // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0033162 // melanosome membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035240 // dopamine binding // inferred from direct assay /// 0035643 // L-DOPA receptor activity // inferred from direct assay /// 0072544 // L-DOPA binding // inferred from direct assay /// 0072545 // tyrosine binding // inferred from direct assay 206697_s_at NM_005143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005143.1 /DEF=Homo sapiens haptoglobin (HP), mRNA. /FEA=mRNA /GEN=HP /PROD=haptoglobin /DB_XREF=gi:4826761 /UG=Hs.75990 haptoglobin /FL=gb:K00422.1 gb:L29394.1 gb:NM_005143.1 NM_005143 haptoglobin HP 3240 NM_001126102 /// NM_005143 /// XM_005255922 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006952 // defense response // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0051354 // negative regulation of oxidoreductase activity // inferred from direct assay /// 2000296 // negative regulation of hydrogen peroxide catabolic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay 206698_at NM_021083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021083.1 /DEF=Homo sapiens Kell blood group precursor (McLeod phenotype) (XK), mRNA. /FEA=mRNA /GEN=XK /PROD=Kell blood group precursor (McLeod phenotype) /DB_XREF=gi:10835266 /UG=Hs.78919 Kell blood group precursor (McLeod phenotype) /FL=gb:NM_021083.1 NM_021083 X-linked Kx blood group XK 7504 NM_021083 0006810 // transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206699_x_at NM_002517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002517.1 /DEF=Homo sapiens neuronal PAS domain protein 1 (NPAS1), mRNA. /FEA=mRNA /GEN=NPAS1 /PROD=neuronal PAS domain protein 1 /DB_XREF=gi:4505426 /UG=Hs.79564 neuronal PAS domain protein 1 /FL=gb:AB054002.1 gb:U77968.1 gb:NM_002517.1 NM_002517 neuronal PAS domain protein 1 NPAS1 4861 NM_002517 /// XM_006723231 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0042711 // maternal behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 206700_s_at NM_004653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004653.1 /DEF=Homo sapiens SMC (mouse) homolog, Y chromosome (SMCY), mRNA. /FEA=mRNA /GEN=SMCY /PROD=SMC (mouse) homolog, Y chromosome /DB_XREF=gi:4759149 /UG=Hs.80358 SMC (mouse) homolog, Y chromosome /FL=gb:U52191.1 gb:NM_004653.1 NM_004653 lysine (K)-specific demethylase 5D KDM5D 8284 NM_001146705 /// NM_001146706 /// NM_004653 /// XM_005262560 /// XM_005262561 /// XM_005262562 /// XM_005262563 /// XR_244571 /// XR_430568 0007283 // spermatogenesis // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 206701_x_at NM_003991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003991.1 /DEF=Homo sapiens endothelin receptor type B (EDNRB), transcript variant 2, mRNA. /FEA=mRNA /GEN=EDNRB /PROD=endothelin receptor type B isoform 2 /DB_XREF=gi:4503466 /UG=Hs.82002 endothelin receptor type B /FL=gb:NM_003991.1 NM_003991 endothelin receptor type B EDNRB 1910 NM_000115 /// NM_001122659 /// NM_001201397 /// NM_003991 /// NR_047024 /// XM_005266275 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014043 // negative regulation of neuron maturation // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014826 // vein smooth muscle contraction // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031620 // regulation of fever generation // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035645 // enteric smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from mutant phenotype /// 0048265 // response to pain // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from direct assay /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // inferred from direct assay /// 0004962 // endothelin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 206702_at NM_000459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000459.1 /DEF=Homo sapiens TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) (TEK), mRNA. /FEA=mRNA /GEN=TEK /PROD=TEK tyrosine kinase, endothelial /DB_XREF=gi:4557868 /UG=Hs.89640 TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) /FL=gb:L06139.1 gb:NM_000459.1 NM_000459 TEK tyrosine kinase, endothelial TEK 7010 NM_000459 /// NM_001290077 /// NM_001290078 /// XM_005251561 /// XM_005251562 /// XM_005251563 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060216 // definitive hemopoiesis // traceable author statement /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 1902533 // positive regulation of intracellular signal transduction // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype /// 2000351 // regulation of endothelial cell apoptotic process // traceable author statement /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 206703_at NM_000747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000747.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) (CHRNB1), mRNA. /FEA=mRNA /GEN=CHRNB1 /PROD=nicotinic aceylcholine receptor beta subunitprecursor /DB_XREF=gi:4557458 /UG=Hs.89739 cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) /FL=gb:NM_000747.1 NM_000747 cholinergic receptor, nicotinic, beta 1 (muscle) CHRNB1 1140 NM_000747 0001941 // postsynaptic membrane organization // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from mutant phenotype /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007271 // synaptic transmission, cholinergic // inferred from mutant phenotype /// 0007274 // neuromuscular synaptic transmission // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from sequence or structural similarity /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0048747 // muscle fiber development // inferred from mutant phenotype /// 0050877 // neurological system process // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from mutant phenotype /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from mutant phenotype /// 0015276 // ligand-gated ion channel activity // inferred from sequence or structural similarity /// 0015464 // acetylcholine receptor activity // inferred from mutant phenotype /// 0042166 // acetylcholine binding // inferred from sequence or structural similarity 206704_at NM_000084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000084.1 /DEF=Homo sapiens chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease) (CLCN5), mRNA. /FEA=mRNA /GEN=CLCN5 /PROD=chloride channel 5 /DB_XREF=gi:4557472 /UG=Hs.89872 chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease) /FL=gb:NM_000084.1 NM_000084 chloride channel, voltage-sensitive 5 CLCN5 1184 NM_000084 /// NM_001127898 /// NM_001127899 /// NM_001272102 /// NM_001282163 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 206705_at NM_003322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003322.2 /DEF=Homo sapiens tubby like protein 1 (TULP1), mRNA. /FEA=mRNA /GEN=TULP1 /PROD=tubby like protein 1 /DB_XREF=gi:6715609 /UG=Hs.93537 tubby like protein 1 /FL=gb:U82468.1 gb:NM_003322.2 NM_003322 tubby like protein 1 TULP1 7287 NM_001289395 /// NM_003322 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0009584 // detection of visible light // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay /// 0045202 // synapse // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008020 // G-protein coupled photoreceptor activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 206706_at NM_002527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002527.2 /DEF=Homo sapiens neurotrophin 3 (NTF3), mRNA. /FEA=mRNA /GEN=NTF3 /PROD=neurotrophin 3 precursor /DB_XREF=gi:9845503 /UG=Hs.99171 neurotrophin 3 /FL=gb:NM_002527.2 NM_002527 neurotrophin 3 NTF3 4908 NM_001102654 /// NM_002527 0000187 // activation of MAPK activity // inferred from direct assay /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008544 // epidermis development // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045687 // positive regulation of glial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005165 // neurotrophin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0048406 // nerve growth factor binding // inferred from electronic annotation 206707_x_at NM_015864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015864.1 /DEF=Homo sapiens chromosome 6 open reading frame 32 (C6ORF32), mRNA. /FEA=mRNA /GEN=C6ORF32 /PROD=PL48 /DB_XREF=gi:7705341 /UG=Hs.101359 chromosome 6 open reading frame 32 /FL=gb:BC001232.1 gb:U49187.1 gb:NM_015864.1 NM_015864 family with sequence similarity 65, member B FAM65B 9750 NM_001286445 /// NM_001286446 /// NM_001286447 /// NM_014722 /// NM_015864 /// XM_006715275 /// XM_006715276 /// XM_006715277 /// XM_006715278 /// XM_006715279 /// XM_006715280 /// XM_006715281 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 206708_at NM_002158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002158.1 /DEF=Homo sapiens human T-cell leukemia virus enhancer factor (HTLF), mRNA. /FEA=mRNA /GEN=HTLF /PROD=T-cell leukemia virus enhancer factor /DB_XREF=gi:4504526 /UG=Hs.103126 human T-cell leukemia virus enhancer factor /FL=gb:U57029.1 gb:NM_002158.1 NM_002158 forkhead box N2 FOXN2 3344 NM_002158 /// XM_005264282 /// XM_005264283 /// XM_005264284 /// XM_005264285 /// XM_006712001 /// XM_006712002 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206709_x_at NM_005309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005309.1 /DEF=Homo sapiens glutamic-pyruvate transaminase (alanine aminotransferase) (GPT), mRNA. /FEA=mRNA /GEN=GPT /PROD=glutamic-pyruvate transaminase (alanineaminotransferase) /DB_XREF=gi:4885350 /UG=Hs.103502 glutamic-pyruvate transaminase (alanine aminotransferase) /FL=gb:NM_005309.1 NM_005309 glutamic-pyruvate transaminase (alanine aminotransferase) GPT 2875 NM_005309 0006094 // gluconeogenesis // non-traceable author statement /// 0006807 // nitrogen compound metabolic process // non-traceable author statement /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042853 // L-alanine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004021 // L-alanine:2-oxoglutarate aminotransferase activity // not recorded /// 0004021 // L-alanine:2-oxoglutarate aminotransferase activity // non-traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 206710_s_at NM_012307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012307.1 /DEF=Homo sapiens differentially expressed in adenocarcinoma of the lung (KIAA0987), mRNA. /FEA=mRNA /GEN=KIAA0987 /PROD=differentially expressed in adenocarcinoma ofthe lung /DB_XREF=gi:6912469 /UG=Hs.103839 erythrocyte membrane protein band 4.1-like 3 /FL=gb:AF069072.1 gb:NM_012307.1 NM_012307 erythrocyte membrane protein band 4.1-like 3 EPB41L3 23136 NM_001281533 /// NM_001281534 /// NM_001281535 /// NM_012307 /// XM_005258085 /// XM_005258086 /// XM_005258087 /// XM_005258088 /// XM_005258089 /// XM_005258090 /// XM_005258091 /// XM_006722301 /// XM_006722302 /// XM_006722303 /// XM_006722304 /// XM_006722305 /// XM_006722306 /// XM_006722307 /// XM_006722308 /// XM_006722309 /// XM_006722310 /// XM_006722311 /// XM_006722312 /// XM_006722313 /// XM_006722314 /// XM_006722315 /// XM_006722316 0002175 // protein localization to paranode region of axon // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0030865 // cortical cytoskeleton organization // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 206711_at NM_004709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004709.1 /DEF=Homo sapiens chromosome X open reading frame 1 (CXORF1), mRNA. /FEA=mRNA /GEN=CXORF1 /PROD=chromosome X open reading frame 1 /DB_XREF=gi:4758099 /UG=Hs.106688 chromosome X open reading frame 1 /FL=gb:NM_004709.1 NM_004709 transmembrane protein 257 TMEM257 9142 NM_004709 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206712_at NM_024719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024719.1 /DEF=Homo sapiens hypothetical protein FLJ22474 (FLJ22474), mRNA. /FEA=mRNA /GEN=FLJ22474 /PROD=hypothetical protein FLJ22474 /DB_XREF=gi:13376022 /UG=Hs.108118 hypothetical protein FLJ22474 /FL=gb:NM_024719.1 NM_024719 growth hormone regulated TBC protein 1 GRTP1 79774 NM_001286732 /// NM_001286733 /// NM_024719 /// XM_005268333 /// XM_005268334 /// XM_006719979 /// XM_006719980 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 206713_at NM_014917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014917.1 /DEF=Homo sapiens netrin G1 (KIAA0976), mRNA. /FEA=mRNA /GEN=KIAA0976 /PROD=netrin G1 /DB_XREF=gi:7662425 /UG=Hs.111224 netrin G1 /FL=gb:AB023193.1 gb:NM_014917.1 NM_014917 netrin G1 NTNG1 22854 NM_001113226 /// NM_001113228 /// NM_014917 /// XM_006710454 /// XM_006710455 /// XM_006710456 /// XM_006710457 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 206714_at NM_001141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001141.1 /DEF=Homo sapiens arachidonate 15-lipoxygenase, second type (ALOX15B), mRNA. /FEA=mRNA /GEN=ALOX15B /PROD=arachidonate 15-lipoxygenase, second type /DB_XREF=gi:4557308 /UG=Hs.111256 arachidonate 15-lipoxygenase, second type /FL=gb:U78294.1 gb:NM_001141.1 NM_001141 arachidonate 15-lipoxygenase, type B ALOX15B 247 NM_001039130 /// NM_001039131 /// NM_001141 0006629 // lipid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030336 // negative regulation of cell migration // traceable author statement /// 0030850 // prostate gland development // non-traceable author statement /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045926 // negative regulation of growth // inferred from direct assay /// 0051122 // hepoxilin biosynthetic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from direct assay 0005506 // iron ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016165 // linoleate 13S-lipoxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0036403 // arachidonate 8(S)-lipoxygenase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050473 // arachidonate 15-lipoxygenase activity // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation 206715_at NM_012252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012252.1 /DEF=Homo sapiens transcription factor EC (TFEC), mRNA. /FEA=mRNA /GEN=TFEC /PROD=transcription factor EC /DB_XREF=gi:6912701 /UG=Hs.113274 transcription factor EC /FL=gb:D43945.1 gb:NM_012252.1 NM_012252 transcription factor EC TFEC 22797 NM_001018058 /// NM_001244583 /// NM_012252 /// XM_006715909 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 206716_at NM_003361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003361.1 /DEF=Homo sapiens uromodulin (uromucoid, Tamm-Horsfall glycoprotein) (UMOD), mRNA. /FEA=mRNA /GEN=UMOD /PROD=uromodulin (uromucoid, Tamm-Horsfallglycoprotein) /DB_XREF=gi:4507832 /UG=Hs.1137 uromodulin (uromucoid, Tamm-Horsfall glycoprotein) /FL=gb:M15881.1 gb:M17778.1 gb:NM_003361.1 NM_003361 uromodulin UMOD 7369 NM_001008389 /// NM_001278614 /// NM_003361 /// XM_006721085 /// XM_006721086 /// XM_006721087 /// XM_006721088 /// XM_006721089 0006968 // cellular defense response // traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007588 // excretion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0048878 // chemical homeostasis // inferred from electronic annotation /// 0072218 // metanephric ascending thin limb development // inferred from electronic annotation /// 0072221 // metanephric distal convoluted tubule development // inferred from electronic annotation /// 0072233 // metanephric thick ascending limb development // inferred from electronic annotation /// 1990266 // neutrophil migration // inferred from direct assay /// 2000021 // regulation of ion homeostasis // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from direct assay 206717_at NM_002472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002472.1 /DEF=Homo sapiens myosin, heavy polypeptide 8, skeletal muscle, perinatal (MYH8), mRNA. /FEA=mRNA /GEN=MYH8 /PROD=myosin, heavy polypeptide 8, skeletal muscle,perinatal /DB_XREF=gi:4505300 /UG=Hs.113973 myosin, heavy polypeptide 8, skeletal muscle, perinatal /FL=gb:M36769.1 gb:NM_002472.1 NM_002472 myosin, heavy chain 8, skeletal muscle, perinatal MYH8 4626 NM_002472 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006936 // muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // inferred by curator /// 0032982 // myosin filament // inferred by curator 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0032027 // myosin light chain binding // traceable author statement /// 0051015 // actin filament binding // traceable author statement 206718_at NM_002315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002315.1 /DEF=Homo sapiens LIM domain only 1 (rhombotin 1) (LMO1), mRNA. /FEA=mRNA /GEN=LMO1 /PROD=LIM domain only 1 /DB_XREF=gi:4505004 /UG=Hs.1149 LIM domain only 1 (rhombotin 1) /FL=gb:M26682.1 gb:NM_002315.1 NM_002315 LIM domain only 1 (rhombotin 1) LMO1 4004 NM_001270428 /// NM_002315 /// NR_073006 /// XM_006718228 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206719_at NM_012451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012451.1 /DEF=Homo sapiens synaptogyrin 4 (SYNGR4), mRNA. /FEA=mRNA /GEN=SYNGR4 /PROD=synaptogyrin 4 /DB_XREF=gi:6912691 /UG=Hs.120857 synaptogyrin 4 /FL=gb:NM_012451.1 NM_012451 synaptogyrin 4 SYNGR4 23546 NM_012451 /// XM_005258693 /// XM_005258694 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206720_at NM_002410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002410.2 /DEF=Homo sapiens mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (MGAT5), mRNA. /FEA=mRNA /GEN=MGAT5 /PROD=alpha-1,3(6)-mannosylglycoproteinbeta-1,6-N-acetyl-glucosaminyltransferase /DB_XREF=gi:6031185 /UG=Hs.121502 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase /FL=gb:AF113921.1 gb:D17716.1 gb:NM_002410.2 NM_002410 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase MGAT5 4249 NM_002410 /// XM_005263666 /// XM_005263668 /// XM_005263669 /// XM_005263670 /// XM_006712534 /// XM_006712535 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030144 // alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity // non-traceable author statement 206721_at NM_021179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021179.1 /DEF=Homo sapiens hypothetical protein LOC57821 (LOC57821), mRNA. /FEA=mRNA /GEN=LOC57821 /PROD=hypothetical protein LOC57821 /DB_XREF=gi:10880974 /UG=Hs.122547 hypothetical protein LOC57821 /FL=gb:NM_021179.1 NM_021179 coiled-coil domain containing 181 CCDC181 57821 NM_021179 /// XM_005245381 /// XM_005245382 /// XM_005245383 /// XM_005245384 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 206722_s_at NM_004720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004720.3 /DEF=Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4 (EDG4), mRNA. /FEA=mRNA /GEN=EDG4 /PROD=endothelial differentiation, lysophosphatidicacid G-protein-coupled receptor, 4 /DB_XREF=gi:11038657 /UG=Hs.122575 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4 /FL=gb:NM_004720.3 gb:AF197929.1 gb:AF011466.1 gb:AF233092.1 NM_004720 lysophosphatidic acid receptor 2 LPAR2 9170 NM_004720 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 206723_s_at AF011466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF011466.1 /DEF=Homo sapiens G protein-coupled receptor Edg-4 mRNA, complete cds. /FEA=mRNA /PROD=G protein-coupled receptor Edg-4 /DB_XREF=gi:2735848 /UG=Hs.122575 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4 /FL=gb:NM_004720.3 gb:AF197929.1 gb:AF011466.1 gb:AF233092.1 AF011466 lysophosphatidic acid receptor 2 LPAR2 9170 NM_004720 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 206724_at NM_003655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003655.1 /DEF=Homo sapiens chromobox homolog 4 (Drosophila Pc class) (CBX4), mRNA. /FEA=mRNA /GEN=CBX4 /PROD=chromobox homolog 4 (Drosophila Pc class) /DB_XREF=gi:4502602 /UG=Hs.123085 chromobox homolog 4 (Drosophila Pc class) /FL=gb:AF013956.1 gb:NM_003655.1 NM_003655 chromobox homolog 4 CBX4 8535 NM_003655 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 206725_x_at NM_006128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006128.1 /DEF=Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant BMP1-2, mRNA. /FEA=mRNA /GEN=BMP1 /PROD=bone morphogenetic protein 1, isoform 2,precursor /DB_XREF=gi:5902807 /UG=Hs.1274 bone morphogenetic protein 1 /FL=gb:NM_006128.1 NM_006128 bone morphogenetic protein 1 BMP1 649 NM_001199 /// NM_006128 /// NM_006129 /// NM_006130 /// NM_006131 /// NM_006132 /// NR_033403 /// NR_033404 /// XM_006716386 /// XR_428315 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206726_at NM_014485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014485.1 /DEF=Homo sapiens prostaglandin D2 synthase, hematopoietic (PGDS), mRNA. /FEA=mRNA /GEN=PGDS /PROD=prostaglandin-D synthase /DB_XREF=gi:7657456 /UG=Hs.128433 prostaglandin D2 synthase, hematopoietic /FL=gb:D82073.1 gb:NM_014485.1 NM_014485 hematopoietic prostaglandin D synthase HPGDS 27306 NM_014485 /// XM_005262932 0001516 // prostaglandin biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007626 // locomotory behavior // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from direct assay /// 0004364 // glutathione transferase activity // inferred from electronic annotation /// 0004667 // prostaglandin-D synthase activity // not recorded /// 0004667 // prostaglandin-D synthase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206727_at K02766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K02766.1 /DEF=Human complement component C9 mRNA, complete cds. /FEA=mRNA /GEN=C9 /DB_XREF=gi:179725 /UG=Hs.1290 complement component 9 /FL=gb:K02766.1 gb:NM_001737.1 K02766 complement component 9 C9 735 NM_001737 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0019836 // hemolysis by symbiont of host erythrocytes // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 206728_at NM_014693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014693.1 /DEF=Homo sapiens KIAA0604 gene product (KIAA0604), mRNA. /FEA=mRNA /GEN=KIAA0604 /PROD=KIAA0604 gene product /DB_XREF=gi:7662199 /UG=Hs.129801 KIAA0604 gene product /FL=gb:AF192531.1 gb:AB011176.1 gb:NM_014693.1 NM_014693 endothelin converting enzyme 2 ECE2 9718 NM_001037324 /// NM_001100120 /// NM_001100121 /// NM_014693 /// NM_032331 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010002 // cardioblast differentiation // inferred from sequence or structural similarity /// 0016486 // peptide hormone processing // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206729_at NM_001243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001243.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), mRNA. /FEA=mRNA /GEN=TNFRSF8 /PROD=CD30 antigen (Ki-1 antigen) /DB_XREF=gi:4507588 /UG=Hs.1314 tumor necrosis factor receptor superfamily, member 8 /FL=gb:D86042.1 gb:M83554.1 gb:NM_001243.1 NM_001243 tumor necrosis factor receptor superfamily, member 8 TNFRSF8 943 NM_001243 /// NM_001281430 /// NM_152942 /// XM_006711049 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from reviewed computational analysis /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045556 // positive regulation of TRAIL biosynthetic process // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // inferred from reviewed computational analysis /// 0005515 // protein binding // inferred from electronic annotation 206730_at NM_007325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007325.1 /DEF=Homo sapiens glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant flip, mRNA. /FEA=mRNA /GEN=GRIA3 /PROD=glutamate receptor precursor isoform flip /DB_XREF=gi:6598324 /UG=Hs.100014 glutamate receptor, ionotrophic, AMPA 3 /FL=gb:U10301.1 gb:NM_007325.1 NM_007325 glutamate receptor, ionotropic, AMPA 3 GRIA3 2892 NM_000828 /// NM_001256743 /// NM_007325 /// NM_181894 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded 206731_at NM_014927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014927.1 /DEF=Homo sapiens KIAA0902 protein (KIAA0902), mRNA. /FEA=mRNA /GEN=KIAA0902 /PROD=KIAA0902 protein /DB_XREF=gi:7662367 /UG=Hs.100527 KIAA0902 protein /FL=gb:AB020709.1 gb:NM_014927.1 NM_014927 connector enhancer of kinase suppressor of Ras 2 CNKSR2 22866 NM_001168647 /// NM_001168648 /// NM_001168649 /// NM_014927 /// XM_005274468 /// XM_005274469 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 206732_at NM_014926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014926.1 /DEF=Homo sapiens KIAA0848 protein (KIAA0848), mRNA. /FEA=mRNA /GEN=KIAA0848 /PROD=KIAA0848 protein /DB_XREF=gi:7662335 /UG=Hs.101745 KIAA0848 protein /FL=gb:AB020655.1 gb:NM_014926.1 NM_014926 SLIT and NTRK-like family, member 3 SLITRK3 22865 NM_014926 /// XM_005247230 0007409 // axonogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206733_at NM_003323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003323.1 /DEF=Homo sapiens tubby like protein 2 (TULP2), mRNA. /FEA=mRNA /GEN=TULP2 /PROD=tubby like protein 2 /DB_XREF=gi:4507736 /UG=Hs.104636 tubby like protein 2 /FL=gb:U82469.1 gb:NM_003323.1 NM_003323 tubby like protein 2 TULP2 7288 NM_003323 /// XM_006723345 /// XM_006723346 /// XM_006723347 /// XM_006723348 /// XM_006723349 0007601 // visual perception // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0032403 // protein complex binding // inferred from direct assay 206734_at NM_003772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003772.1 /DEF=Homo sapiens jerky (mouse) homolog-like (JRKL), mRNA. /FEA=mRNA /GEN=JRKL /PROD=jerky (mouse) homolog-like /DB_XREF=gi:4504806 /UG=Hs.105940 jerky (mouse) homolog-like /FL=gb:AF004715.1 gb:NM_003772.1 NM_003772 JRK-like JRKL 8690 NM_001261833 /// NM_003772 0007417 // central nervous system development // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation 206735_at NM_000744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000744.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 4 (CHRNA4), mRNA. /FEA=mRNA /GEN=CHRNA4 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 4 /DB_XREF=gi:4502826 /UG=Hs.10734 cholinergic receptor, nicotinic, alpha polypeptide 4 /FL=gb:U62433.1 gb:NM_000744.1 gb:L35901.1 NM_000744 cholinergic receptor, nicotinic, alpha 4 (neuronal) CHRNA4 1137 NM_000744 /// NM_001256573 /// NR_046317 /// XM_005260191 0001508 // action potential // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0035640 // exploration behavior // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 206736_x_at L35901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L35901.1 /DEF=Human nicotinic acetylcholine receptor alpha 4 subunit (nAChR) mRNA, complete cds. /FEA=mRNA /GEN=nAChR /PROD=nicotinic acetylcholine receptor alpha 4subunit /DB_XREF=gi:755647 /UG=Hs.10734 cholinergic receptor, nicotinic, alpha polypeptide 4 /FL=gb:U62433.1 gb:NM_000744.1 gb:L35901.1 L35901 cholinergic receptor, nicotinic, alpha 4 (neuronal) CHRNA4 1137 NM_000744 /// NM_001256573 /// NR_046317 /// XM_005260191 0001508 // action potential // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0035640 // exploration behavior // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 206737_at NM_004626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004626.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 11 (WNT11), mRNA. /FEA=mRNA /GEN=WNT11 /PROD=wingless-type MMTV integration site family,member 11 /DB_XREF=gi:4759319 /UG=Hs.108219 wingless-type MMTV integration site family, member 11 /FL=gb:NM_004626.1 NM_004626 wingless-type MMTV integration site family, member 11 WNT11 7481 NM_004626 /// XM_005274231 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030325 // adrenal gland development // inferred from expression pattern /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032915 // positive regulation of transforming growth factor beta2 production // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048706 // embryonic skeletal system development // inferred from expression pattern /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from expression pattern /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from expression pattern /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0060675 // ureteric bud morphogenesis // inferred from expression pattern /// 0061037 // negative regulation of cartilage development // non-traceable author statement /// 0061101 // neuroendocrine cell differentiation // inferred from mutant phenotype /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072201 // negative regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090272 // negative regulation of fibroblast growth factor production // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation 0005099 // Ras GTPase activator activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 206738_at NM_001646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001646.1 /DEF=Homo sapiens apolipoprotein C-IV (APOC4), mRNA. /FEA=mRNA /GEN=APOC4 /PROD=apolipoprotein C-IV /DB_XREF=gi:4502160 /UG=Hs.110675 apolipoprotein C-IV /FL=gb:NM_001646.1 NM_001646 apolipoprotein C-II /// apolipoprotein C-IV /// APOC4-APOC2 readthrough (NMD candidate) APOC2 /// APOC4 /// APOC4-APOC2 344 /// 346 /// 100533990 NM_000483 /// NM_001646 /// NR_037932 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from direct assay /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0010902 // positive regulation of very-low-density lipoprotein particle remodeling // inferred by curator /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032375 // negative regulation of cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034370 // triglyceride-rich lipoprotein particle remodeling // traceable author statement /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred by curator /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred by curator /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from direct assay /// 0060697 // positive regulation of phospholipid catabolic process // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from mutant phenotype /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005319 // lipid transporter activity // traceable author statement /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0043274 // phospholipase binding // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060230 // lipoprotein lipase activator activity // inferred from direct assay 206739_at NM_018953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018953.1 /DEF=Homo sapiens homeo box C5 (HOXC5), mRNA. /FEA=mRNA /GEN=HOXC5 /PROD=homeo box C5 /DB_XREF=gi:11321637 /UG=Hs.111473 homeo box C5 /FL=gb:NM_018953.1 NM_018953 homeobox C5 HOXC5 3222 NM_018953 /// NR_003084 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206740_x_at NM_003176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003176.1 /DEF=Homo sapiens synaptonemal complex protein 1 (SYCP1), mRNA. /FEA=mRNA /GEN=SYCP1 /PROD=synaptonemal complex protein 1 /DB_XREF=gi:4507326 /UG=Hs.112743 synaptonemal complex protein 1 /FL=gb:D67035.1 gb:NM_003176.1 NM_003176 synaptonemal complex protein 1 SYCP1 6847 NM_001282541 /// NM_001282542 /// NM_003176 /// NR_104211 /// XM_005271154 /// XM_005271155 /// XM_005271156 /// XM_006710859 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // inferred from electronic annotation /// 0000801 // central element // inferred from electronic annotation /// 0000802 // transverse filament // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206741_at NM_015931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015931.1 /DEF=Homo sapiens fls485 (LOC51066), mRNA. /FEA=mRNA /GEN=LOC51066 /PROD=fls485 /DB_XREF=gi:7705707 /UG=Hs.113019 fls485 /FL=gb:AB024705.1 gb:NM_015931.1 NM_015931 ssu-2 homolog (C. elegans) SSUH2 51066 NM_001256748 /// NM_001256749 /// NM_015931 /// NR_046358 /// XM_005265193 /// XM_005265194 /// XM_006713186 /// XR_427277 0005737 // cytoplasm // inferred from direct assay 0031072 // heat shock protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 206742_at NM_004469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004469.1 /DEF=Homo sapiens c-fos induced growth factor (vascular endothelial growth factor D) (FIGF), mRNA. /FEA=mRNA /GEN=FIGF /PROD=c-fos induced growth factor (vascularendothelial growth factor D) /DB_XREF=gi:4758377 /UG=Hs.11392 c-fos induced growth factor (vascular endothelial growth factor D) /FL=gb:D89630.1 gb:NM_004469.1 NM_004469 c-fos induced growth factor (vascular endothelial growth factor D) /// PIR-FIGF readthrough FIGF /// PIR-FIGF 2277 /// 100532742 NM_004469 /// NR_037859 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030224 // monocyte differentiation // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0003712 // transcription cofactor activity // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // traceable author statement /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005172 // vascular endothelial growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008127 // quercetin 2,3-dioxygenase activity // inferred from direct assay /// 0008127 // quercetin 2,3-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043185 // vascular endothelial growth factor receptor 3 binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 206743_s_at NM_001671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001671.1 /DEF=Homo sapiens asialoglycoprotein receptor 1 (ASGR1), mRNA. /FEA=mRNA /GEN=ASGR1 /PROD=asialoglycoprotein receptor 1 /DB_XREF=gi:4502250 /UG=Hs.12056 asialoglycoprotein receptor 1 /FL=gb:M10058.1 gb:NM_001671.1 NM_001671 asialoglycoprotein receptor 1 ASGR1 432 NM_001197216 /// NM_001671 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004873 // asialoglycoprotein receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206744_s_at NM_014242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014242.1 /DEF=Homo sapiens zinc finger protein 237 (ZNF237), mRNA. /FEA=mRNA /GEN=ZNF237 /PROD=zinc finger protein 237 /DB_XREF=gi:7657706 /UG=Hs.124386 zinc finger protein 237 /FL=gb:NM_014242.1 NM_014242 zinc finger, MYM-type 5 ZMYM5 9205 NM_001039649 /// NM_001039650 /// NM_001142684 /// NM_014242 /// XM_005266593 /// XM_005266594 /// XM_005266595 /// XM_006719894 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206745_at NM_014212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014212.1 /DEF=Homo sapiens homeo box C11 (HOXC11), mRNA. /FEA=mRNA /GEN=HOXC11 /PROD=homeo box C11 /DB_XREF=gi:7657165 /UG=Hs.127562 homeo box C11 /FL=gb:NM_014212.1 NM_014212 homeobox C11 HOXC11 3227 NM_014212 0001501 // skeletal system development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206746_at NM_001195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001195.2 /DEF=Homo sapiens beaded filament structural protein 1, filensin (BFSP1), mRNA. /FEA=mRNA /GEN=BFSP1 /PROD=filensin /DB_XREF=gi:13518027 /UG=Hs.129702 beaded filament structural protein 1, filensin /FL=gb:Y16717.2 gb:NM_001195.2 gb:AF039655.1 NM_001195 beaded filament structural protein 1, filensin BFSP1 631 NM_001161705 /// NM_001195 /// NM_001278606 /// NM_001278607 /// NM_001278608 0048469 // cell maturation // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206747_at NM_014696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014696.1 /DEF=Homo sapiens KIAA0514 gene product (KIAA0514), mRNA. /FEA=mRNA /GEN=KIAA0514 /PROD=KIAA0514 gene product /DB_XREF=gi:7662165 /UG=Hs.129739 KIAA0514 gene product /FL=gb:AB011086.1 gb:NM_014696.1 NM_014696 G protein regulated inducer of neurite outgrowth 2 GPRIN2 9721 NM_014696 /// XM_005270329 /// XM_005277666 0005515 // protein binding // inferred from physical interaction 206748_s_at NM_003971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003971.1 /DEF=Homo sapiens sperm associated antigen 9 (SPAG9), mRNA. /FEA=mRNA /GEN=SPAG9 /PROD=sperm associated antigen 9 /DB_XREF=gi:4504524 /UG=Hs.129872 sperm associated antigen 9 /FL=gb:NM_003971.1 NM_003971 sperm associated antigen 9 SPAG9 9043 NM_001130527 /// NM_001130528 /// NM_001251971 /// NM_003971 /// NM_172345 /// XM_005257767 /// XM_005257768 /// XM_005257769 /// XM_005257770 /// XM_005257771 /// XM_005257772 /// XM_005257773 /// XM_005257774 /// XM_006722163 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from electronic annotation 206749_at NM_001764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001764.1 /DEF=Homo sapiens CD1B antigen, b polypeptide (CD1B), mRNA. /FEA=mRNA /GEN=CD1B /PROD=CD1B antigen, b polypeptide /DB_XREF=gi:4502644 /UG=Hs.1310 CD1B antigen, b polypeptide /FL=gb:M28826.1 gb:NM_001764.1 NM_001764 CD1b molecule CD1B 910 NM_001764 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030883 // endogenous lipid antigen binding // not recorded /// 0030884 // exogenous lipid antigen binding // not recorded /// 0071723 // lipopeptide binding // not recorded 206750_at NM_002360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002360.1 /DEF=Homo sapiens v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein K (MAFK), mRNA. /FEA=mRNA /GEN=MAFK /PROD=v-maf musculoaponeurotic fibrosarcoma (avian)oncogene family, protein K /DB_XREF=gi:4505074 /UG=Hs.131953 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein K /FL=gb:AF059194.1 gb:NM_002360.1 NM_002360 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K MAFK 7975 NM_002360 /// XM_005249851 /// XM_006715773 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206751_s_at NM_004845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004845.1 /DEF=Homo sapiens phosphate cytidylyltransferase 1, choline, beta isoform (PCYT1B), mRNA. /FEA=mRNA /GEN=PCYT1B /PROD=phosphate cytidylyltransferase 1, choline, betaisoform /DB_XREF=gi:4758889 /UG=Hs.132794 phosphate cytidylyltransferase 1, choline, beta isoform /FL=gb:AF052510.1 gb:NM_004845.1 NM_004845 phosphate cytidylyltransferase 1, choline, beta PCYT1B 9468 NM_001163264 /// NM_001163265 /// NM_004845 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 206752_s_at NM_004402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004402.1 /DEF=Homo sapiens DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase) (DFFB), mRNA. /FEA=mRNA /GEN=DFFB /PROD=DNA fragmentation factor, 40 kD, betapolypeptide /DB_XREF=gi:4758149 /UG=Hs.133089 DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase) /FL=gb:AF039210.1 gb:AF064019.1 gb:AB013918.1 gb:NM_004402.1 NM_004402 DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) DFFB 1677 NM_001004285 /// NM_001004286 /// NM_001282669 /// NM_004402 /// NR_104222 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004516 // nicotinate phosphoribosyltransferase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 206753_at AF086735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF086735.1 /DEF=Homo sapiens retinol dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=retinol dehydrogenase /DB_XREF=gi:3859945 /UG=Hs.134958 microsomal NAD+-dependent retinol dehydrogenase 4 /FL=gb:AF057034.1 gb:AF086735.1 gb:NM_003708.1 AF086735 retinol dehydrogenase 16 (all-trans) RDH16 8608 NM_003708 /// XM_005269205 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004745 // retinol dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 206754_s_at NM_000767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000767.2 /DEF=Homo sapiens cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 (CYP2B6), mRNA. /FEA=mRNA /GEN=CYP2B6 /PROD=cytochrome P450, subfamily IIB(phenobarbital-inducible), polypeptide 6 /DB_XREF=gi:13699814 /UG=Hs.1360 cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 /FL=gb:NM_000767.2 gb:M29874.1 gb:AF182277.1 NM_000767 cytochrome P450, family 2, subfamily B, polypeptide 6 /// cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene CYP2B6 /// CYP2B7P 1555 /// 1556 NM_000767 /// NR_001278 /// XM_005258569 /// XM_006723050 /// XM_006723051 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042180 // cellular ketone metabolic process // inferred from direct assay /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206755_at NM_000767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000767.2 /DEF=Homo sapiens cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 (CYP2B6), mRNA. /FEA=mRNA /GEN=CYP2B6 /PROD=cytochrome P450, subfamily IIB(phenobarbital-inducible), polypeptide 6 /DB_XREF=gi:13699814 /UG=Hs.1360 cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 /FL=gb:NM_000767.2 gb:M29874.1 gb:AF182277.1 NM_000767 cytochrome P450, family 2, subfamily B, polypeptide 6 CYP2B6 1555 NM_000767 /// XM_005258569 /// XM_006723050 /// XM_006723051 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042180 // cellular ketone metabolic process // inferred from direct assay /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 206756_at NM_019886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019886.1 /DEF=Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 (CHST7), mRNA. /FEA=mRNA /GEN=CHST7 /PROD=carbohydrate (N-acetylglucosamine 6-O)sulfotransferase 7 /DB_XREF=gi:9845239 /UG=Hs.138155 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 /FL=gb:AB040711.1 gb:AB037187.1 gb:NM_019886.1 NM_019886 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 CHST7 56548 NM_019886 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008459 // chondroitin 6-sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 206757_at NM_001083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001083.1 /DEF=Homo sapiens phosphodiesterase 5A, cGMP-specific (PDE5A), mRNA. /FEA=mRNA /GEN=PDE5A /PROD=phosphodiesterase 5A /DB_XREF=gi:4505666 /UG=Hs.139271 phosphodiesterase 5A, cGMP-specific /FL=gb:D89094.1 gb:AF043731.1 gb:NM_001083.1 gb:AB015656.1 NM_001083 phosphodiesterase 5A, cGMP-specific PDE5A 8654 NM_001083 /// NM_033430 /// NM_033437 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from direct assay /// 0046069 // cGMP catabolic process // inferred from electronic annotation /// 0055118 // negative regulation of cardiac muscle contraction // inferred from electronic annotation /// 0055119 // relaxation of cardiac muscle // inferred from electronic annotation /// 0060282 // positive regulation of oocyte development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 206758_at NM_001956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001956.1 /DEF=Homo sapiens endothelin 2 (EDN2), mRNA. /FEA=mRNA /GEN=EDN2 /PROD=endothelin 2 /DB_XREF=gi:4503462 /UG=Hs.1407 endothelin 2 /FL=gb:M65199.1 gb:NM_001956.1 NM_001956 endothelin 2 EDN2 1907 NM_001956 /// XM_005270566 /// XM_006710400 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0003058 // hormonal regulation of the force of heart contraction // traceable author statement /// 0003099 // positive regulation of the force of heart contraction by chemical signal // traceable author statement /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred by curator /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010460 // positive regulation of heart rate // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from direct assay /// 0014826 // vein smooth muscle contraction // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0042116 // macrophage activation // inferred from direct assay /// 0042310 // vasoconstriction // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0060585 // positive regulation of prostaglandin-endoperoxide synthase activity // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005179 // hormone activity // inferred from direct assay 206759_at NM_002002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002002.1 /DEF=Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23A) (FCER2), mRNA. /FEA=mRNA /GEN=FCER2 /PROD=Fc fragment of IgE, low affinity II, receptorfor (CD23A) /DB_XREF=gi:4503678 /UG=Hs.1416 Fc fragment of IgE, low affinity II, receptor for (CD23A) /FL=gb:M15059.1 gb:M14766.1 gb:NM_002002.1 NM_002002 Fc fragment of IgE, low affinity II, receptor for (CD23) FCER2 2208 NM_001207019 /// NM_001220500 /// NM_002002 /// XM_005272462 /// XM_006722687 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051712 // positive regulation of killing of cells of other organism // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0019863 // IgE binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206760_s_at NM_002002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002002.1 /DEF=Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23A) (FCER2), mRNA. /FEA=mRNA /GEN=FCER2 /PROD=Fc fragment of IgE, low affinity II, receptorfor (CD23A) /DB_XREF=gi:4503678 /UG=Hs.1416 Fc fragment of IgE, low affinity II, receptor for (CD23A) /FL=gb:M15059.1 gb:M14766.1 gb:NM_002002.1 NM_002002 Fc fragment of IgE, low affinity II, receptor for (CD23) FCER2 2208 NM_001207019 /// NM_001220500 /// NM_002002 /// XM_005272462 /// XM_006722687 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051712 // positive regulation of killing of cells of other organism // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0019863 // IgE binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206761_at NM_005816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005816.1 /DEF=Homo sapiens T cell activation, increased late expression (TACTILE), mRNA. /FEA=mRNA /GEN=TACTILE /PROD=T cell activation, increased late expression /DB_XREF=gi:5032140 /UG=Hs.142023 T cell activation, increased late expression /FL=gb:M88282.1 gb:NM_005816.1 NM_005816 CD96 molecule CD96 10225 NM_005816 /// NM_198196 /// XM_005247063 /// XM_006713469 /// XM_006713470 /// XR_241462 /// XR_241466 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206762_at NM_002234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002234.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5), mRNA. /FEA=mRNA /GEN=KCNA5 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 5 /DB_XREF=gi:4504818 /UG=Hs.150208 potassium voltage-gated channel, shaker-related subfamily, member 5 /FL=gb:M55513.1 gb:M83254.1 gb:M60451.1 gb:NM_002234.1 NM_002234 potassium voltage-gated channel, shaker-related subfamily, member 5 KCNA5 3741 NM_002234 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043266 // regulation of potassium ion transport // inferred from mutant phenotype /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055075 // potassium ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071435 // potassium ion export // inferred from direct assay /// 0071435 // potassium ion export // inferred from mutant phenotype /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0046691 // intracellular canaliculus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from mutant phenotype /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from direct assay /// 0015271 // outward rectifier potassium channel activity // inferred from mutant phenotype /// 0019870 // potassium channel inhibitor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from physical interaction /// 0086089 // voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0097110 // scaffold protein binding // inferred from physical interaction 206763_at NM_003602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003602.1 /DEF=Homo sapiens FK506-binding protein 6 (36kD) (FKBP6), mRNA. /FEA=mRNA /GEN=FKBP6 /PROD=FK506-binding protein 6 (36kD) /DB_XREF=gi:4503730 /UG=Hs.150490 FK506-binding protein 6 (36kD) /FL=gb:AF038847.1 gb:NM_003602.1 NM_003602 FK506 binding protein 6, 36kDa FKBP6 8468 NM_001135211 /// NM_001281304 /// NM_003602 /// XM_005250643 /// XM_006716152 /// XM_006716153 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded 0000795 // synaptonemal complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from sequence or structural similarity 206764_x_at NM_023075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023075.1 /DEF=Homo sapiens hypothetical protein FLJ11585 (FLJ11585), mRNA. /FEA=mRNA /GEN=FLJ11585 /PROD=hypothetical protein FLJ11585 /DB_XREF=gi:12751486 /UG=Hs.154145 hypothetical protein FLJ11585 /FL=gb:NM_023075.1 NM_023075 metallophosphoesterase 1 MPPE1 65258 NM_001242904 /// NM_023075 /// NM_138608 /// NR_040241 /// NR_040242 /// NR_040243 /// XM_006722340 /// XM_006722341 /// XM_006722342 /// XM_006722343 /// XM_006722344 /// XM_006722345 /// XM_006722346 /// XM_006722347 /// XM_006722348 /// XM_006722349 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from sequence or structural similarity 0008081 // phosphoric diester hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 206765_at AF153820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153820.1 /DEF=Homo sapiens inwardly-rectifying potassium channel Kir2.1 (KCNJ2) mRNA, complete cds. /FEA=mRNA /GEN=KCNJ2 /PROD=inwardly-rectifying potassium channel Kir2.1 /DB_XREF=gi:8132296 /UG=Hs.1547 potassium inwardly-rectifying channel, subfamily J, member 2 /FL=gb:AF011904.1 gb:AF021139.1 gb:NM_000891.1 gb:U16861.1 gb:U12507.1 gb:U22413.1 gb:AF153820.1 gb:U24055.1 AF153820 potassium inwardly-rectifying channel, subfamily J, member 2 KCNJ2 3759 NM_000891 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0010107 // potassium ion import // inferred from direct assay /// 0014861 // regulation of skeletal muscle contraction via regulation of action potential // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0030007 // cellular potassium ion homeostasis // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055119 // relaxation of cardiac muscle // inferred from mutant phenotype /// 0060075 // regulation of resting membrane potential // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086001 // cardiac muscle cell action potential // inferred from electronic annotation /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation /// 0086011 // membrane repolarization during action potential // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // traceable author statement /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // traceable author statement /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090076 // relaxation of skeletal muscle // inferred from mutant phenotype /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from electronic annotation 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype 206766_at AF112345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112345.1 /DEF=Homo sapiens integrin alpha 10 subunit (ITGA10) mRNA, complete cds. /FEA=mRNA /GEN=ITGA10 /PROD=integrin alpha 10 subunit /DB_XREF=gi:6650627 /UG=Hs.158237 integrin, alpha 10 /FL=gb:AF074015.1 gb:NM_003637.2 gb:AF112345.1 AF112345 integrin, alpha 10 ITGA10 8515 NM_003637 /// XM_005277432 /// XM_005277433 /// XM_005277434 /// XM_005277435 /// XM_005277436 /// XM_006711596 /// XR_254331 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005518 // collagen binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206767_at NM_014483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014483.1 /DEF=Homo sapiens RNA binding motif, single stranded interacting protein 3 (RBMS3), mRNA. /FEA=mRNA /GEN=RBMS3 /PROD=RNA binding motif, single stranded interactingprotein 3 /DB_XREF=gi:7657505 /UG=Hs.158446 RNA binding motif, single stranded interacting protein 3 /FL=gb:AF023259.1 gb:NM_014483.1 NM_014483 RNA binding motif, single stranded interacting protein 3 RBMS3 27303 NM_001003792 /// NM_001003793 /// NM_001177711 /// NM_001177712 /// NM_014483 /// XM_005265060 /// XM_005265061 /// XM_005265062 /// XM_005265063 /// XM_005265064 /// XM_005265065 /// XM_006713108 /// XM_006713109 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 206768_at NM_005061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005061.1 /DEF=Homo sapiens ribosomal protein L3-like (RPL3L), mRNA. /FEA=mRNA /GEN=RPL3L /PROD=ribosomal protein L3-like /DB_XREF=gi:4826987 /UG=Hs.159191 ribosomal protein L3-like /FL=gb:U65581.1 gb:NM_005061.1 NM_005061 ribosomal protein L3-like RPL3L 6123 NM_005061 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 206769_at NM_004202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004202.1 /DEF=Homo sapiens thymosin, beta 4, Y chromosome (TMSB4Y), mRNA. /FEA=mRNA /GEN=TMSB4Y /PROD=thymosin, beta 4, Y chromosome /DB_XREF=gi:4759243 /UG=Hs.159201 thymosin, beta 4, Y chromosome /FL=gb:AF000989.1 gb:NM_004202.1 NM_004202 thymosin beta 4, Y-linked TMSB4Y 9087 NM_004202 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0042989 // sequestering of actin monomers // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206770_s_at NM_012243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012243.1 /DEF=Homo sapiens solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 (SLC35A3), mRNA. /FEA=mRNA /GEN=SLC35A3 /PROD=solute carrier family 35(UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member3 /DB_XREF=gi:6912667 /UG=Hs.159322 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 /FL=gb:AB021981.1 gb:NM_012243.1 NM_012243 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 SLC35A3 23443 NM_001271684 /// NM_001271685 /// NM_012243 /// XM_005270691 /// XM_005270693 /// XM_006710516 /// XM_006710517 0006047 // UDP-N-acetylglucosamine metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015788 // UDP-N-acetylglucosamine transport // inferred from mutant phenotype /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005462 // UDP-N-acetylglucosamine transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206771_at NM_006953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006953.1 /DEF=Homo sapiens uroplakin 3 (UPK3), mRNA. /FEA=mRNA /GEN=UPK3 /PROD=uroplakin 3 /DB_XREF=gi:5902151 /UG=Hs.159330 uroplakin 3 /FL=gb:AB010637.1 gb:AF085808.1 gb:NM_006953.1 NM_006953 uroplakin 3A UPK3A 7380 NM_001167574 /// NM_006953 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0015840 // urea transport // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0055075 // potassium ion homeostasis // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 206772_at NM_005048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005048.1 /DEF=Homo sapiens parathyroid hormone receptor 2 (PTHR2), mRNA. /FEA=mRNA /GEN=PTHR2 /PROD=parathyroid hormone receptor 2 /DB_XREF=gi:4826953 /UG=Hs.159499 parathyroid hormone receptor 2 /FL=gb:NM_005048.1 gb:U25128.1 NM_005048 parathyroid hormone 2 receptor PTH2R 5746 NM_005048 /// NR_073601 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004991 // parathyroid hormone receptor activity // traceable author statement 206773_at NM_002347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002347.1 /DEF=Homo sapiens lymphocyte antigen 6 complex, locus H (LY6H), mRNA. /FEA=mRNA /GEN=LY6H /PROD=lymphocyte antigen 6 complex, locus H /DB_XREF=gi:4505050 /UG=Hs.159590 lymphocyte antigen 6 complex, locus H /FL=gb:AB012293.1 gb:NM_002347.1 NM_002347 lymphocyte antigen 6 complex, locus H LY6H 4062 NM_001130478 /// NM_001135655 /// NM_002347 /// XM_006716559 /// XM_006725098 0007399 // nervous system development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 206774_at NM_014907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014907.1 /DEF=Homo sapiens KIAA0967 protein (KIAA0967), mRNA. /FEA=mRNA /GEN=KIAA0967 /PROD=KIAA0967 protein /DB_XREF=gi:7662415 /UG=Hs.163990 KIAA0967 protein /FL=gb:AB023184.1 gb:NM_014907.1 NM_014907 FERM and PDZ domain containing 1 FRMPD1 22844 NM_014907 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 206775_at NM_001081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001081.1 /DEF=Homo sapiens cubilin (intrinsic factor-cobalamin receptor) (CUBN), mRNA. /FEA=mRNA /GEN=CUBN /PROD=cubilin precursor /DB_XREF=gi:4557502 /UG=Hs.166206 cubilin (intrinsic factor-cobalamin receptor) /FL=gb:AF034611.1 gb:NM_001081.1 NM_001081 cubilin (intrinsic factor-cobalamin receptor) CUBN 8029 NM_001081 0001894 // tissue homeostasis // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015889 // cobalamin transport // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042359 // vitamin D metabolic process // traceable author statement /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031232 // extrinsic component of external side of plasma membrane // non-traceable author statement /// 0031526 // brush border membrane // non-traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206776_x_at NM_001612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001612.2 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform aprecursor /DB_XREF=gi:9955946 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:M82968.1 gb:NM_001612.2 NM_001612 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 206777_s_at NM_000496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000496.1 /DEF=Homo sapiens crystallin, beta B2 (CRYBB2), mRNA. /FEA=mRNA /GEN=CRYBB2 /PROD=crystallin, beta B2 /DB_XREF=gi:4503062 /UG=Hs.169286 crystallin, beta B2 /FL=gb:L10035.1 gb:NM_000496.1 NM_000496 crystallin, beta B2 /// crystallin, beta B2 pseudogene 1 CRYBB2 /// CRYBB2P1 1415 /// 1416 NM_000496 /// NR_033733 /// NR_033734 /// XM_006724141 0007601 // visual perception // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 206778_at NM_000496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000496.1 /DEF=Homo sapiens crystallin, beta B2 (CRYBB2), mRNA. /FEA=mRNA /GEN=CRYBB2 /PROD=crystallin, beta B2 /DB_XREF=gi:4503062 /UG=Hs.169286 crystallin, beta B2 /FL=gb:L10035.1 gb:NM_000496.1 NM_000496 crystallin, beta B2 CRYBB2 1415 NM_000496 /// XM_006724141 0007601 // visual perception // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 206779_s_at NM_004043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004043.1 /DEF=Homo sapiens acetylserotonin O-methyltransferase (ASMT), mRNA. /FEA=mRNA /GEN=ASMT /PROD=acetylserotonin O-methyltransferase /DB_XREF=gi:4757791 /UG=Hs.169609 acetylserotonin O-methyltransferase /FL=gb:M83779.1 gb:NM_004043.1 gb:U11091.1 NM_004043 acetylserotonin O-methyltransferase ASMT 438 NM_001171038 /// NM_001171039 /// NM_004043 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042113 // B cell activation // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 2000019 // negative regulation of male gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 206780_at NM_000818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000818.1 /DEF=Homo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kD) (GAD2), mRNA. /FEA=mRNA /GEN=GAD2 /PROD=glutamate decarboxylase 2 /DB_XREF=gi:4503874 /UG=Hs.170808 glutamate decarboxylase 2 (pancreatic islets and brain, 65kD) /FL=gb:M74826.1 gb:NM_000818.1 NM_000818 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) GAD2 2572 NM_000818 /// NM_001134366 0006540 // glutamate decarboxylation to succinate // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206781_at NM_005528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005528.1 /DEF=Homo sapiens heat shock 40kD protein 2 (HSPF2), mRNA. /FEA=mRNA /GEN=HSPF2 /PROD=heat shock 40kD protein 2 /DB_XREF=gi:5031770 /UG=Hs.172847 DnaJ (Hsp40) homolog, subfamily C, member 4 /FL=gb:AF012106.1 gb:NM_005528.1 NM_005528 DnaJ (Hsp40) homolog, subfamily C, member 4 DNAJC4 3338 NM_005528 /// XM_006718529 /// XM_006718530 0006457 // protein folding // non-traceable author statement /// 0006986 // response to unfolded protein // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 206782_s_at NM_005528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005528.1 /DEF=Homo sapiens heat shock 40kD protein 2 (HSPF2), mRNA. /FEA=mRNA /GEN=HSPF2 /PROD=heat shock 40kD protein 2 /DB_XREF=gi:5031770 /UG=Hs.172847 DnaJ (Hsp40) homolog, subfamily C, member 4 /FL=gb:AF012106.1 gb:NM_005528.1 NM_005528 DnaJ (Hsp40) homolog, subfamily C, member 4 DNAJC4 3338 NM_005528 /// XM_006718529 /// XM_006718530 0006457 // protein folding // non-traceable author statement /// 0006986 // response to unfolded protein // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 206783_at BF510715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF510715 /FEA=EST /DB_XREF=gi:11594013 /DB_XREF=est:UI-H-BI4-aoh-b-05-0-UI.s1 /CLONE=IMAGE:3084633 /UG=Hs.1755 fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) /FL=gb:M17446.1 gb:NM_002007.1 BF510715 fibroblast growth factor 4 FGF4 2249 NM_002007 /// XM_005273847 /// XM_006718475 0001502 // cartilage condensation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010463 // mesenchymal cell proliferation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 0060561 // apoptotic process involved in morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 206784_at NM_001169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001169.1 /DEF=Homo sapiens aquaporin 8 (AQP8), mRNA. /FEA=mRNA /GEN=AQP8 /PROD=aquaporin 8 /DB_XREF=gi:4502188 /UG=Hs.176658 aquaporin 8 /FL=gb:AB013456.1 gb:NM_001169.1 gb:AF067797.1 NM_001169 aquaporin 8 AQP8 343 NM_001169 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0015722 // canalicular bile acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071320 // cellular response to cAMP // inferred from expression pattern 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0046691 // intracellular canaliculus // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015250 // water channel activity // traceable author statement 206785_s_at NM_002260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002260.2 /DEF=Homo sapiens killer cell lectin-like receptor subfamily C, member 2 (KLRC2), mRNA. /FEA=mRNA /GEN=KLRC2 /PROD=killer cell lectin-like receptor subfamily C,member 2 /DB_XREF=gi:7108353 /UG=Hs.177605 killer cell lectin-like receptor subfamily C, member 2 /FL=gb:NM_002260.2 gb:AF260134.1 NM_002260 killer cell lectin-like receptor subfamily C, member 1 /// killer cell lectin-like receptor subfamily C, member 2 KLRC1 /// KLRC2 3821 /// 3822 NM_002259 /// NM_002260 /// NM_007328 /// NM_213657 /// NM_213658 /// XM_005253360 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 206786_at NM_000200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000200.1 /DEF=Homo sapiens histatin 3 (HTN3), mRNA. /FEA=mRNA /GEN=HTN3 /PROD=histatin 3 /DB_XREF=gi:4557652 /UG=Hs.177888 histatin 3 /FL=gb:M18372.1 gb:M26665.1 gb:NM_000200.1 NM_000200 histatin 3 HTN3 3347 NM_000200 0031214 // biomineral tissue development // inferred from electronic annotation /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // non-traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206787_at NM_001726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001726.1 /DEF=Homo sapiens bromodomain, testis-specific (BRDT), mRNA. /FEA=mRNA /GEN=BRDT /PROD=testis-specific bromodomain protein /DB_XREF=gi:4502452 /UG=Hs.178281 bromodomain, testis-specific /FL=gb:AF019085.1 gb:NM_001726.1 NM_001726 bromodomain, testis-specific BRDT 676 NM_001242805 /// NM_001242806 /// NM_001242807 /// NM_001242808 /// NM_001242810 /// NM_001726 /// NM_207189 /// XM_005271151 /// XM_006710853 /// XM_006710854 /// XM_006710855 /// XM_006710856 /// XM_006710857 /// XM_006710858 0001207 // histone displacement // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007141 // male meiosis I // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from sequence or structural similarity /// 0051039 // positive regulation of transcription during meiosis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // traceable author statement /// 0042393 // histone binding // inferred from direct assay /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 206788_s_at AF294326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF294326.1 /DEF=Homo sapiens core binding factor beta isoform PEBP2B mRNA, complete cds. /FEA=mRNA /PROD=core binding factor beta isoform PEBP2B /DB_XREF=gi:9885832 /UG=Hs.179881 core-binding factor, beta subunit /FL=gb:NM_022845.1 gb:AF294326.1 AF294326 core-binding factor, beta subunit CBFB 865 NM_001755 /// NM_022845 /// XM_005256212 /// XM_006721321 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206789_s_at NM_002697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002697.1 /DEF=Homo sapiens POU domain, class 2, transcription factor 1 (POU2F1), mRNA. /FEA=mRNA /GEN=POU2F1 /PROD=POU domain, class 2, transcription factor 1 /DB_XREF=gi:4505956 /UG=Hs.182237 POU domain, class 2, transcription factor 1 /FL=gb:NM_002697.1 NM_002697 POU class 2 homeobox 1 POU2F1 5451 NM_001198783 /// NM_001198786 /// NM_002697 /// NR_037163 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030910 // olfactory placode formation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206790_s_at NM_004545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004545.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 (7kD, MNLL) (NDUFB1), mRNA. /FEA=mRNA /GEN=NDUFB1 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 1 (7kD, MNLL) /DB_XREF=gi:4758775 /UG=Hs.183435 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 (7kD, MNLL) /FL=gb:AF054181.1 gb:NM_004545.1 NM_004545 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa NDUFB1 4707 NM_004545 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 206791_s_at BF511742 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511742 /FEA=EST /DB_XREF=gi:11595040 /DB_XREF=est:UI-H-BI4-aom-h-08-0-UI.s1 /CLONE=IMAGE:3085670 /UG=Hs.189 phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E1) /FL=gb:NM_000923.1 BF511742 uncharacterized LOC729966 /// phosphodiesterase 4C, cAMP-specific LOC729966 /// PDE4C 5143 /// 729966 NM_000923 /// NM_001098818 /// NM_001098819 /// NR_036575 /// NR_040546 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // traceable author statement /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206792_x_at NM_000923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000923.1 /DEF=Homo sapiens phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E1) (PDE4C), mRNA. /FEA=mRNA /GEN=PDE4C /PROD=phosphodiesterase 4C, cAMP-specific (dunce(Drosophila)-homolog phosphodiesterase E1) /DB_XREF=gi:4505664 /UG=Hs.189 phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E1) /FL=gb:NM_000923.1 NM_000923 uncharacterized LOC729966 /// phosphodiesterase 4C, cAMP-specific LOC729966 /// PDE4C 5143 /// 729966 NM_000923 /// NM_001098818 /// NM_001098819 /// NR_036575 /// NR_040546 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // traceable author statement /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206793_at NM_002686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002686.1 /DEF=Homo sapiens phenylethanolamine N-methyltransferase (PNMT), mRNA. /FEA=mRNA /GEN=PNMT /PROD=phenylethanolamine N-methyltransferase /DB_XREF=gi:4505920 /UG=Hs.1892 phenylethanolamine N-methyltransferase /FL=gb:J03727.1 gb:NM_002686.1 NM_002686 phenylethanolamine N-methyltransferase PNMT 5409 NM_002686 /// NR_073461 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042418 // epinephrine biosynthetic process // inferred from electronic annotation /// 0042423 // catecholamine biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004603 // phenylethanolamine N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206794_at NM_005235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005235.1 /DEF=Homo sapiens v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 (ERBB4), mRNA. /FEA=mRNA /GEN=ERBB4 /PROD=v-erb-a avian erythroblastic leukemia viraloncogene homolog-like 4 /DB_XREF=gi:4885214 /UG=Hs.1939 v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 /FL=gb:L07868.1 gb:NM_005235.1 NM_005235 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 ERBB4 2066 NM_001042599 /// NM_005235 /// XM_005246375 /// XM_005246376 /// XM_005246377 /// XM_006712364 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021551 // central nervous system morphogenesis // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060644 // mammary gland epithelial cell differentiation // inferred from sequence or structural similarity /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061026 // cardiac muscle tissue regeneration // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000366 // positive regulation of STAT protein import into nucleus // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 206795_at NM_004101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004101.1 /DEF=Homo sapiens coagulation factor II (thrombin) receptor-like 2 (F2RL2), mRNA. /FEA=mRNA /GEN=F2RL2 /PROD=coagulation factor II (thrombin) receptor-like 2precursor /DB_XREF=gi:4758325 /UG=Hs.194351 coagulation factor II (thrombin) receptor-like 2 /FL=gb:U92971.1 gb:NM_004101.1 NM_004101 coagulation factor II (thrombin) receptor-like 2 F2RL2 2151 NM_001256566 /// NM_004101 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // inferred from electronic annotation 206796_at NM_003882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003882.1 /DEF=Homo sapiens WNT1 inducible signaling pathway protein 1 (WISP1), mRNA. /FEA=mRNA /GEN=WISP1 /PROD=WNT1 inducible signaling pathway protein 1 /DB_XREF=gi:4507920 /UG=Hs.194680 WNT1 inducible signaling pathway protein 1 /FL=gb:AF100779.1 gb:NM_003882.1 NM_003882 WNT1 inducible signaling pathway protein 1 WISP1 8840 NM_001204869 /// NM_001204870 /// NM_003882 /// NM_080838 /// NR_037944 /// XM_006716680 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation 206797_at NM_000015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000015.1 /DEF=Homo sapiens N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), mRNA. /FEA=mRNA /GEN=NAT2 /PROD=arylamide acetylase 2 /DB_XREF=gi:4557782 /UG=Hs.2 N-acetyltransferase 2 (arylamine N-acetyltransferase) /FL=gb:NM_000015.1 NM_000015 N-acetyltransferase 2 (arylamine N-acetyltransferase) NAT2 10 NM_000015 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004060 // arylamine N-acetyltransferase activity // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 206798_x_at NM_005106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005106.2 /DEF=Homo sapiens deleted in lung and esophageal cancer 1 (DLEC1), transcript variant DLEC1-N1, mRNA. /FEA=mRNA /GEN=DLEC1 /PROD=deleted in lung and esophageal cancer 1, isoformDLEC1-N1 /DB_XREF=gi:6715589 /UG=Hs.200188 deleted in lung and esophageal cancer 1 /FL=gb:AB020522.1 gb:NM_005106.2 NM_005106 deleted in lung and esophageal cancer 1 DLEC1 9940 NM_007335 /// NM_007336 /// NM_007337 /// NM_007338 /// XM_005265630 /// XM_005265631 /// XM_006713437 /// XM_006713438 /// XM_006713439 /// XM_006713440 /// XM_006713441 /// XR_427301 /// XR_427302 0008285 // negative regulation of cell proliferation // traceable author statement 0005737 // cytoplasm // inferred from direct assay 206799_at NM_006551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006551.2 /DEF=Homo sapiens lipophilin B (uteroglobin family member), prostatein-like (LPHB), mRNA. /FEA=mRNA /GEN=LPHB /PROD=lipophilin B precursor /DB_XREF=gi:10947028 /UG=Hs.204096 lipophilin B (uteroglobin family member), prostatein-like /FL=gb:NM_006551.2 NM_006551 secretoglobin, family 1D, member 2 SCGB1D2 10647 NM_006551 /// XM_006718422 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 206800_at NM_005957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005957.1 /DEF=Homo sapiens 5,10-methylenetetrahydrofolate reductase (NADPH) (MTHFR), mRNA. /FEA=mRNA /GEN=MTHFR /PROD=5,10-methylenetetrahydrofolate reductase(NADPH) /DB_XREF=gi:6631097 /UG=Hs.214142 5,10-methylenetetrahydrofolate reductase (NADPH) /FL=gb:NM_005957.1 NM_005957 methylenetetrahydrofolate reductase (NAD(P)H) MTHFR 4524 NM_005957 /// XM_005263458 /// XM_005263460 /// XM_005263461 /// XM_005263462 /// XM_005263463 0001666 // response to hypoxia // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006555 // methionine metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0033274 // response to vitamin B2 // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004489 // methylenetetrahydrofolate reductase (NAD(P)H) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 206801_at NM_002521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002521.1 /DEF=Homo sapiens natriuretic peptide precursor B (NPPB), mRNA. /FEA=mRNA /GEN=NPPB /PROD=natriuretic peptide precursor B /DB_XREF=gi:4505432 /UG=Hs.219140 natriuretic peptide precursor B /FL=gb:M25296.1 gb:NM_002521.1 NM_002521 natriuretic peptide B NPPB 4879 NM_002521 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0007589 // body fluid secretion // traceable author statement /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0035810 // positive regulation of urine volume // traceable author statement /// 0035815 // positive regulation of renal sodium excretion // traceable author statement /// 0042312 // regulation of vasodilation // non-traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005179 // hormone activity // non-traceable author statement /// 0008613 // diuretic hormone activity // traceable author statement 206802_at NM_016734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016734.1 /DEF=Homo sapiens paired box gene 5 (B-cell lineage specific activator protein) (PAX5), mRNA. /FEA=mRNA /GEN=PAX5 /PROD=paired box 5 /DB_XREF=gi:9951919 /UG=Hs.22030 paired box gene 5 (B-cell lineage specific activator protein) /FL=gb:M96944.1 gb:NM_016734.1 NM_016734 paired box 5 PAX5 5079 NM_001280547 /// NM_001280548 /// NM_001280549 /// NM_001280550 /// NM_001280551 /// NM_001280552 /// NM_001280553 /// NM_001280554 /// NM_001280555 /// NM_001280556 /// NM_016734 /// NR_103999 /// NR_104000 /// XM_005251481 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 206803_at NM_024411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024411.1 /DEF=Homo sapiens prodynorphin (PDYN), mRNA. /FEA=mRNA /GEN=PDYN /PROD=prodynorphin /DB_XREF=gi:13270472 /UG=Hs.22584 prodynorphin /FL=gb:NM_024411.1 NM_024411 prodynorphin PDYN 5173 NM_001190892 /// NM_001190898 /// NM_001190899 /// NM_001190900 /// NM_024411 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0001515 // opioid peptide activity // inferred from electronic annotation 206804_at NM_000073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000073.1 /DEF=Homo sapiens CD3G antigen, gamma polypeptide (TiT3 complex) (CD3G), mRNA. /FEA=mRNA /GEN=CD3G /PROD=CD3G gamma precursor /DB_XREF=gi:4557428 /UG=Hs.2259 CD3G antigen, gamma polypeptide (TiT3 complex) /FL=gb:NM_000073.1 NM_000073 CD3g molecule, gamma (CD3-TCR complex) CD3G 917 NM_000073 /// XM_005271724 /// XM_005271725 /// XM_006718941 0006461 // protein complex assembly // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // inferred from mutant phenotype /// 0015031 // protein transport // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0070228 // regulation of lymphocyte apoptotic process // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // non-traceable author statement /// 0042105 // alpha-beta T cell receptor complex // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0042608 // T cell receptor binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 206805_at NM_006080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006080.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (SEMA3A), mRNA. /FEA=mRNA /GEN=SEMA3A /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3A /DB_XREF=gi:5174672 /UG=Hs.2414 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A /FL=gb:NM_006080.1 gb:L26081.1 NM_006080 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A SEMA3A 10371 NM_006080 /// XM_005250110 /// XM_005250111 /// XM_006715838 /// XM_006715839 0001764 // neuron migration // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021772 // olfactory bulb development // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048841 // regulation of axon extension involved in axon guidance // inferred from direct assay /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048880 // sensory system development // traceable author statement /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0060385 // axonogenesis involved in innervation // inferred from sequence or structural similarity /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // traceable author statement /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1901166 // neural crest cell migration involved in autonomic nervous system development // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation /// 0038191 // neuropilin binding // inferred from sequence or structural similarity /// 0045499 // chemorepellent activity // traceable author statement 206806_at NM_004717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004717.1 /DEF=Homo sapiens diacylglycerol kinase, iota (DGKI), mRNA. /FEA=mRNA /GEN=DGKI /PROD=diacylglycerol kinase, iota /DB_XREF=gi:4758155 /UG=Hs.242947 diacylglycerol kinase, iota /FL=gb:AF061936.1 gb:NM_004717.1 NM_004717 diacylglycerol kinase, iota DGKI 9162 NM_004717 /// XM_006716172 /// XM_006716173 /// XM_006716174 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032317 // regulation of Rap GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206807_s_at NM_017482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017482.1 /DEF=Homo sapiens adducin 2 (beta) (ADD2), transcript variant beta-2, mRNA. /FEA=mRNA /GEN=ADD2 /PROD=adducin 2, isoform b /DB_XREF=gi:9257177 /UG=Hs.247423 adducin 2 (beta) /FL=gb:NM_017482.1 NM_017482 adducin 2 (beta) ADD2 119 NM_001185054 /// NM_001185055 /// NM_001617 /// NM_017482 /// NM_017483 /// NM_017484 /// NM_017485 /// NM_017486 /// NM_017487 /// NM_017488 0006461 // protein complex assembly // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 206808_at NM_005758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005758.1 /DEF=Homo sapiens heterogeneous nuclear protein similar to rat helix destabilizing protein (FBRNP), mRNA. /FEA=mRNA /GEN=FBRNP /PROD=heterogeneous nuclear protein similar to rathelix destabilizing protein /DB_XREF=gi:5031692 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein /FL=gb:NM_005758.1 NM_005758 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 HNRNPA3P1 10151 NR_002726 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation 206809_s_at NM_005758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005758.1 /DEF=Homo sapiens heterogeneous nuclear protein similar to rat helix destabilizing protein (FBRNP), mRNA. /FEA=mRNA /GEN=FBRNP /PROD=heterogeneous nuclear protein similar to rathelix destabilizing protein /DB_XREF=gi:5031692 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein /FL=gb:NM_005758.1 NM_005758 heterogeneous nuclear ribonucleoprotein A3 /// heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 HNRNPA3 /// HNRNPA3P1 10151 /// 220988 NM_194247 /// NR_002726 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 206810_at NM_016264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016264.1 /DEF=Homo sapiens GIOT-2 for gonadotropin inducible transcription repressor-2 (GIOT-2), mRNA. /FEA=mRNA /GEN=GIOT-2 /PROD=gonadotropin inducible transcriptionrepressor-2 /DB_XREF=gi:7706462 /UG=Hs.251371 GIOT-2 for gonadotropin inducible transcription repressor-2 /FL=gb:AB021642.1 gb:NM_016264.1 NM_016264 zinc finger protein ZnFP12-like /// zinc finger protein 44 LOC101060181 /// ZNF44 51710 /// 101060181 NM_001164276 /// NM_016264 /// XM_003959953 /// XM_003960761 /// XM_003960891 /// XM_005259934 /// XM_005259935 /// XM_006722768 /// XM_006722954 /// XM_006726772 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206811_at NM_001115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001115.1 /DEF=Homo sapiens adenylate cyclase 8 (brain) (ADCY8), mRNA. /FEA=mRNA /GEN=ADCY8 /PROD=adenylate cyclase 8 /DB_XREF=gi:4557256 /UG=Hs.2522 adenylate cyclase 8 (brain) /FL=gb:NM_001115.1 NM_001115 adenylate cyclase 8 (brain) ADCY8 114 NM_001115 /// XM_005250769 /// XM_006716501 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206812_at NM_000025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000025.1 /DEF=Homo sapiens adrenergic, beta-3-, receptor (ADRB3), mRNA. /FEA=mRNA /GEN=ADRB3 /PROD=adrenergic, beta-3-, receptor /DB_XREF=gi:4557266 /UG=Hs.2549 adrenergic, beta-3-, receptor /FL=gb:NM_000025.1 NM_000025 adrenoceptor beta 3 ADRB3 155 NM_000025 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0002025 // vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002032 // desensitization of G-protein coupled receptor protein signaling pathway by arrestin // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0031649 // heat generation // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from direct assay /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004939 // beta-adrenergic receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015052 // beta3-adrenergic receptor activity // inferred from mutant phenotype /// 0031699 // beta-3 adrenergic receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051379 // epinephrine binding // inferred from electronic annotation /// 0051380 // norepinephrine binding // inferred from direct assay 206813_at NM_001330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001330.1 /DEF=Homo sapiens cardiotrophin 1 (CTF1), mRNA. /FEA=mRNA /GEN=CTF1 /PROD=cardiotrophin 1 /DB_XREF=gi:4503120 /UG=Hs.25537 cardiotrophin 1 /FL=gb:U43030.1 gb:NM_001330.1 NM_001330 cardiotrophin 1 CTF1 1489 NM_001142544 /// NM_001330 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005146 // leukemia inhibitory factor receptor binding // inferred from electronic annotation 206814_at NM_002506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002506.1 /DEF=Homo sapiens nerve growth factor, beta polypeptide (NGFB), mRNA. /FEA=mRNA /GEN=NGFB /PROD=nerve growth factor, beta polypeptide /DB_XREF=gi:4505390 /UG=Hs.2561 nerve growth factor, beta polypeptide /FL=gb:NM_002506.1 NM_002506 nerve growth factor (beta polypeptide) NGF 4803 NM_002506 /// XM_006710663 /// XM_006710664 /// XM_006710665 0000186 // activation of MAPKK activity // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010193 // response to ozone // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from electronic annotation /// 0032455 // nerve growth factor processing // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051388 // positive regulation of neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000648 // positive regulation of stem cell proliferation // inferred from electronic annotation /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005796 // Golgi lumen // traceable author statement 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005163 // nerve growth factor receptor binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 206815_at NM_012436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012436.1 /DEF=Homo sapiens sperm associated antigen 8 (SPAG8), mRNA. /FEA=mRNA /GEN=SPAG8 /PROD=sperm associated antigen 8 /DB_XREF=gi:6912671 /UG=Hs.256747 sperm associated antigen 8 /FL=gb:U12978.2 gb:NM_012436.1 NM_012436 sperm associated antigen 8 SPAG8 26206 NM_001039592 /// NM_012436 /// NM_172312 /// XM_005251436 /// XM_005251437 /// XM_005251438 /// XM_006716753 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 206816_s_at NM_012436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012436.1 /DEF=Homo sapiens sperm associated antigen 8 (SPAG8), mRNA. /FEA=mRNA /GEN=SPAG8 /PROD=sperm associated antigen 8 /DB_XREF=gi:6912671 /UG=Hs.256747 sperm associated antigen 8 /FL=gb:U12978.2 gb:NM_012436.1 NM_012436 sperm associated antigen 8 SPAG8 26206 NM_001039592 /// NM_012436 /// NM_172312 /// XM_005251436 /// XM_005251437 /// XM_005251438 /// XM_006716753 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation 206817_x_at NM_007185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007185.1 /DEF=Homo sapiens trinucleotide repeat containing 4 (TNRC4), mRNA. /FEA=mRNA /GEN=TNRC4 /PROD=trinucleotide repeat containing 4 /DB_XREF=gi:6005724 /UG=Hs.26047 trinucleotide repeat containing 4 /FL=gb:AF329264.1 gb:U80759.1 gb:NM_007185.1 NM_007185 CUGBP, Elav-like family member 3 CELF3 11189 NM_001172648 /// NM_001172649 /// NM_001291106 /// NM_001291107 /// NM_007185 /// XM_005244858 /// XM_005244859 /// XM_006711139 /// XM_006711140 /// XM_006711141 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0030317 // sperm motility // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from mutant phenotype /// 0003729 // mRNA binding // non-traceable author statement 206818_s_at NM_017649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017649.1 /DEF=Homo sapiens hypothetical protein FLJ20064 (FLJ20064), mRNA. /FEA=mRNA /GEN=FLJ20064 /PROD=hypothetical protein FLJ20064 /DB_XREF=gi:8923070 /UG=Hs.271221 hypothetical protein FLJ20064 /FL=gb:NM_017649.1 NM_017649 cyclin M2 CNNM2 54805 NM_017649 /// NM_199076 /// NM_199077 /// XM_005269933 /// XM_006717908 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0016311 // dephosphorylation // /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017144 // drug metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008253 // 5'-nucleotidase activity // /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0008253 // 5'-nucleotidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050146 // nucleoside phosphotransferase activity // traceable author statement 206819_at NM_014549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014549.1 /DEF=Homo sapiens DKFZp434P211 protein (DKFZP434P211), mRNA. /FEA=mRNA /GEN=DKFZP434P211 /PROD=DKFZp434P211 protein /DB_XREF=gi:7657020 /UG=Hs.278387 DKFZp434P211 protein /FL=gb:AL117401.1 gb:NM_014549.1 NM_014549 POM121 transmembrane nucleoporin-like 9, pseudogene POM121L9P 29774 NM_014549 /// NR_003714 206820_at AF015042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF015042.1 /DEF=Homo sapiens RAB-R protein (RAB-R) mRNA, complete cds. /FEA=mRNA /GEN=RAB-R /PROD=RAB-R protein /DB_XREF=gi:4102708 /UG=Hs.278502 RevRex activation domain binding protein-related /FL=gb:AF015042.1 gb:NM_006076.1 AF015042 ArfGAP with FG repeats 2 AGFG2 3268 NM_006076 /// XM_005250306 /// XM_006715958 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206821_x_at NM_006076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006076.1 /DEF=Homo sapiens RevRex activation domain binding protein-related (RAB-R), mRNA. /FEA=mRNA /GEN=RAB-R /PROD=RevRex activation domain bindingprotein-related /DB_XREF=gi:5174648 /UG=Hs.278502 RevRex activation domain binding protein-related /FL=gb:AF015042.1 gb:NM_006076.1 NM_006076 ArfGAP with FG repeats 2 AGFG2 3268 NM_006076 /// XM_005250306 /// XM_006715958 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206822_s_at NM_015478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015478.1 /DEF=Homo sapiens DKFZP586P1522 protein (DKFZP586P1522), mRNA. /FEA=mRNA /GEN=DKFZP586P1522 /PROD=DKFZP586P1522 protein /DB_XREF=gi:7661701 /UG=Hs.278516 DKFZP586P1522 protein /FL=gb:NM_015478.1 NM_015478 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206823_at NM_015478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015478.1 /DEF=Homo sapiens DKFZP586P1522 protein (DKFZP586P1522), mRNA. /FEA=mRNA /GEN=DKFZP586P1522 /PROD=DKFZP586P1522 protein /DB_XREF=gi:7661701 /UG=Hs.278516 DKFZP586P1522 protein /FL=gb:NM_015478.1 NM_015478 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206824_at NM_016280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016280.1 /DEF=Homo sapiens carboxylesterase-related protein (LOC51716), mRNA. /FEA=mRNA /GEN=LOC51716 /PROD=carboxylesterase-related protein /DB_XREF=gi:7706474 /UG=Hs.278997 carboxylesterase-related protein /FL=gb:AF106005.1 gb:NM_016280.1 NM_016280 carboxylesterase 1 pseudogene 1 CES1P1 51716 NM_016280 /// NR_003276 0008152 // metabolic process // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement 0052689 // carboxylic ester hydrolase activity // traceable author statement 206825_at NM_000916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000916.2 /DEF=Homo sapiens oxytocin receptor (OXTR), mRNA. /FEA=mRNA /GEN=OXTR /PROD=oxytocin receptor /DB_XREF=gi:12707575 /UG=Hs.2820 oxytocin receptor /FL=gb:NM_000916.2 NM_000916 oxytocin receptor OXTR 5021 NM_000916 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010701 // positive regulation of norepinephrine secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0034059 // response to anoxia // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044058 // regulation of digestive system process // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0060455 // negative regulation of gastric acid secretion // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004990 // oxytocin receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation 206826_at NM_002677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002677.1 /DEF=Homo sapiens peripheral myelin protein 2 (PMP2), mRNA. /FEA=mRNA /GEN=PMP2 /PROD=peripheral myelin protein 2 /DB_XREF=gi:4505908 /UG=Hs.2868 peripheral myelin protein 2 /FL=gb:NM_002677.1 NM_002677 peripheral myelin protein 2 PMP2 5375 NM_002677 0006810 // transport // inferred from electronic annotation /// 0061024 // membrane organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 206827_s_at NM_014274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014274.1 /DEF=Homo sapiens Alu-binding protein with zinc finger domain (ABPZF), mRNA. /FEA=mRNA /GEN=ABPZF /PROD=Alu-binding protein with zinc finger domain /DB_XREF=gi:7656846 /UG=Hs.289104 Alu-binding protein with zinc finger domain /FL=gb:U82613.1 gb:NM_014274.1 NM_014274 transient receptor potential cation channel, subfamily V, member 6 TRPV6 55503 NM_014274 /// NM_018646 /// XM_006716043 /// XM_006716044 /// XM_006716045 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay 206828_at NM_003328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003328.1 /DEF=Homo sapiens TXK tyrosine kinase (TXK), mRNA. /FEA=mRNA /GEN=TXK /PROD=TXK tyrosine kinase /DB_XREF=gi:4507742 /UG=Hs.29877 TXK tyrosine kinase /FL=gb:NM_003328.1 gb:L27071.1 NM_003328 TXK tyrosine kinase TXK 7294 NM_003328 0001816 // cytokine production // inferred from sequence or structural similarity /// 0001865 // NK T cell differentiation // inferred from electronic annotation /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0032633 // interleukin-4 production // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001012 // RNA polymerase II regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 206829_x_at NM_025189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025189.1 /DEF=Homo sapiens hypothetical protein FLJ13659 (FLJ13659), mRNA. /FEA=mRNA /GEN=FLJ13659 /PROD=hypothetical protein FLJ13659 /DB_XREF=gi:13430887 /UG=Hs.301651 hypothetical protein FLJ13659 /FL=gb:NM_025189.1 NM_025189 zinc finger protein 430 ZNF430 80264 NM_001172671 /// NM_025189 /// XM_005260081 /// XM_005260082 /// XM_005260083 /// XM_006722909 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206830_at NM_022058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022058.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 (SLC4A10), mRNA. /FEA=mRNA /GEN=SLC4A10 /PROD=solute carrier family 4, sodium bicarbonatecotransporter-like, member 10 /DB_XREF=gi:11545762 /UG=Hs.304962 solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 /FL=gb:AB040457.1 gb:NM_022058.1 NM_022058 solute carrier family 4, sodium bicarbonate transporter, member 10 SLC4A10 57282 NM_001178015 /// NM_001178016 /// NM_022058 /// XM_005246693 /// XM_005246694 /// XM_005246695 /// XM_005246696 /// XM_006712641 /// XM_006712642 /// XM_006712643 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0006885 // regulation of pH // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 206831_s_at NM_001669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001669.1 /DEF=Homo sapiens arylsulfatase D (ARSD), transcript variant 1, mRNA. /FEA=mRNA /GEN=ARSD /PROD=arylsulfatase D precursor, isoform a /DB_XREF=gi:4502238 /UG=Hs.326525 arylsulfatase D /FL=gb:NM_001669.1 gb:X83572.1 NM_001669 arylsulfatase D ARSD 414 NM_001669 /// NM_009589 /// XM_005274514 /// XM_005274515 /// XM_005274516 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206832_s_at NM_004186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004186.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (SEMA3F), mRNA. /FEA=mRNA /GEN=SEMA3F /PROD=Semaphorin IV /DB_XREF=gi:4759089 /UG=Hs.32981 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F /FL=gb:U33920.1 gb:NM_004186.1 NM_004186 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F SEMA3F 6405 NM_004186 /// XM_005265381 /// XM_005265382 /// XM_006713289 /// XM_006713290 0001755 // neural crest cell migration // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from direct assay 206833_s_at NM_001108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001108.1 /DEF=Homo sapiens acylphosphatase 2, muscle type (ACYP2), mRNA. /FEA=mRNA /GEN=ACYP2 /PROD=acylphosphatase 2, muscle type /DB_XREF=gi:4557246 /UG=Hs.331598 acylphosphatase 2, muscle type /FL=gb:NM_001108.1 NM_001108 acylphosphatase 2, muscle type /// uncharacterized LOC101927144 ACYP2 /// LOC101927144 98 /// 101927144 NM_138448 /// XR_245004 /// XR_249130 /// XR_251075 /// XR_425399 /// XR_427031 /// XR_431425 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003998 // acylphosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation 206834_at NM_000519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000519.2 /DEF=Homo sapiens hemoglobin, delta (HBD), mRNA. /FEA=mRNA /GEN=HBD /PROD=hemoglobin, delta /DB_XREF=gi:6633803 /UG=Hs.36977 hemoglobin, delta /FL=gb:NM_000519.2 NM_000519 hemoglobin, delta HBD 3045 NM_000519 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206835_at NM_003154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003154.1 /DEF=Homo sapiens statherin (STATH), mRNA. /FEA=mRNA /GEN=STATH /PROD=statherin /DB_XREF=gi:4507260 /UG=Hs.37048 statherin /FL=gb:M18078.1 gb:M18371.1 gb:NM_003154.1 NM_003154 statherin STATH 6779 NM_001009181 /// NM_003154 0001503 // ossification // traceable author statement /// 0030502 // negative regulation of bone mineralization // non-traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0046541 // saliva secretion // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement /// 0030345 // structural constituent of tooth enamel // non-traceable author statement /// 0046848 // hydroxyapatite binding // non-traceable author statement 206836_at NM_001044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001044.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (SLC6A3), mRNA. /FEA=mRNA /GEN=SLC6A3 /PROD=solute carrier family 6 (neurotransmittertransporter, dopamine), member 3 /DB_XREF=gi:4507040 /UG=Hs.406 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 /FL=gb:L24178.1 gb:NM_001044.1 gb:M95167.1 NM_001044 solute carrier family 6 (neurotransmitter transporter), member 3 SLC6A3 6531 NM_001044 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015844 // monoamine transport // inferred from direct assay /// 0015872 // dopamine transport // inferred from direct assay /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060134 // prepulse inhibition // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005329 // dopamine transmembrane transporter activity // inferred from direct assay /// 0005330 // dopamine:sodium symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035240 // dopamine binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 206837_at NM_006982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006982.1 /DEF=Homo sapiens cartilage paired-class homeoprotein 1 (CART1), mRNA. /FEA=mRNA /GEN=CART1 /PROD=cartilage paired-class homeoprotein 1 /DB_XREF=gi:5901917 /UG=Hs.41683 cartilage paired-class homeoprotein 1 /FL=gb:U31986.1 gb:NM_006982.1 NM_006982 ALX homeobox 1 ALX1 8092 NM_006982 /// XM_005269165 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001502 // cartilage condensation // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007420 // brain development // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206838_at NM_005149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005149.1 /DEF=Homo sapiens T-box 19 (TBX19), mRNA. /FEA=mRNA /GEN=TBX19 /PROD=T-box 19 /DB_XREF=gi:4827023 /UG=Hs.50403 T-box 19 /FL=gb:NM_005149.1 NM_005149 T-box 19 TBX19 9095 NM_005149 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206839_at NM_015370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015370.1 /DEF=Homo sapiens hypothetical protein (HS747E2A), mRNA. /FEA=mRNA /GEN=HS747E2A /PROD=hypothetical protein /DB_XREF=gi:7657193 /UG=Hs.50891 hypothetical protein /FL=gb:NM_015370.1 NM_015370 chromosome 22 open reading frame 31 C22orf31 25770 NM_015370 /// XM_005261490 /// XM_005261491 206840_at NM_001133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001133.1 /DEF=Homo sapiens afamin (AFM), mRNA. /FEA=mRNA /GEN=AFM /PROD=afamin /DB_XREF=gi:4501986 /UG=Hs.531 afamin /FL=gb:NM_001133.1 gb:L32140.1 NM_001133 afamin AFM 173 NM_001133 /// XM_006714122 0006810 // transport // inferred from electronic annotation /// 0051180 // vitamin transport // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0008431 // vitamin E binding // inferred from direct assay 206841_at NM_006205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006205.1 /DEF=Homo sapiens phosphodiesterase 6H, cGMP-specific, cone, gamma (PDE6H), mRNA. /FEA=mRNA /GEN=PDE6H /PROD=phosphodiesterase 6H, cGMP-specific, cone,gamma /DB_XREF=gi:5453867 /UG=Hs.54471 phosphodiesterase 6H, cGMP-specific, cone, gamma /FL=gb:D45399.1 gb:NM_006205.1 NM_006205 phosphodiesterase 6H, cGMP-specific, cone, gamma PDE6H 5149 NM_006205 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 206842_at NM_004979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004979.1 /DEF=Homo sapiens potassium voltage-gated channel, Shal-related family, member 1 (KCND1), mRNA. /FEA=mRNA /GEN=KCND1 /PROD=potassium voltage-gated channel, Shal-relatedfamily, member 1 /DB_XREF=gi:4826791 /UG=Hs.55276 potassium voltage-gated channel, Shal-related subfamily, member 1 /FL=gb:AJ005898.1 gb:NM_004979.1 gb:AF166003.1 gb:AB021865.1 NM_004979 potassium voltage-gated channel, Shal-related subfamily, member 1 KCND1 3750 NM_004979 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // non-traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206843_at NM_001886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001886.1 /DEF=Homo sapiens crystallin, beta A4 (CRYBA4), mRNA. /FEA=mRNA /GEN=CRYBA4 /PROD=crystallin, beta A4 /DB_XREF=gi:4503058 /UG=Hs.57690 crystallin, beta A4 /FL=gb:U59057.1 gb:NM_001886.1 NM_001886 crystallin, beta A4 CRYBA4 1413 NM_001886 /// XM_006724140 0007601 // visual perception // inferred from mutant phenotype /// 0007601 // visual perception // non-traceable author statement /// 0043010 // camera-type eye development // inferred from mutant phenotype 0005212 // structural constituent of eye lens // inferred from electronic annotation 206844_at NM_003837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003837.1 /DEF=Homo sapiens fructose-1,6-bisphosphatase 2 (FBP2), mRNA. /FEA=mRNA /GEN=FBP2 /PROD=fructose-1,6-bisphosphatase 2 /DB_XREF=gi:4503670 /UG=Hs.61255 fructose-1,6-bisphosphatase 2 /FL=gb:NM_003837.1 NM_003837 fructose-1,6-bisphosphatase 2 FBP2 8789 NM_003837 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042132 // fructose 1,6-bisphosphate 1-phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206845_s_at NM_014771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014771.1 /DEF=Homo sapiens 95 kDa retinoblastoma protein binding protein; KIAA0661 gene product (KIAA0661), mRNA. /FEA=mRNA /GEN=KIAA0661 /PROD=95 kDa retinoblastoma protein binding protein;KIAA0661 gene product /DB_XREF=gi:7662229 /UG=Hs.65238 95 kDa retinoblastoma protein binding protein; KIAA0661 gene product /FL=gb:AB014561.1 gb:NM_014771.1 NM_014771 ring finger protein 40, E3 ubiquitin protein ligase RNF40 9810 NM_001207033 /// NM_001207034 /// NM_001286572 /// NM_014771 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033523 // histone H2B ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0033503 // HULC complex // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206846_s_at NM_006044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006044.2 /DEF=Homo sapiens histone deacetylase 6 (HDAC6), mRNA. /FEA=mRNA /GEN=HDAC6 /PROD=histone deacetylase 6 /DB_XREF=gi:13128863 /UG=Hs.6764 histone deacetylase 6 /FL=gb:NM_006044.2 gb:AB020708.1 gb:AF132609.1 NM_006044 histone deacetylase 6 HDAC6 10013 NM_006044 /// XM_005272564 /// XM_005272565 /// XM_005272566 /// XM_005272568 /// XM_006724525 /// XR_246712 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from mutant phenotype /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010033 // response to organic substance // inferred from mutant phenotype /// 0010469 // regulation of receptor activity // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010727 // negative regulation of hydrogen peroxide metabolic process // inferred by curator /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0032418 // lysosome localization // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0035967 // cellular response to topologically incorrect protein // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0043241 // protein complex disassembly // inferred from electronic annotation /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051354 // negative regulation of oxidoreductase activity // inferred by curator /// 0051788 // response to misfolded protein // inferred from mutant phenotype /// 0060632 // regulation of microtubule-based movement // inferred by curator /// 0060765 // regulation of androgen receptor signaling pathway // traceable author statement /// 0070201 // regulation of establishment of protein localization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from mutant phenotype /// 0070845 // polyubiquitinated misfolded protein transport // inferred from mutant phenotype /// 0070846 // Hsp90 deacetylation // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0071218 // cellular response to misfolded protein // inferred from electronic annotation /// 0090035 // positive regulation of chaperone-mediated protein complex assembly // inferred from mutant phenotype /// 0090042 // tubulin deacetylation // inferred from direct assay /// 0090042 // tubulin deacetylation // inferred from sequence or structural similarity /// 1901300 // positive regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0030286 // dynein complex // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from direct assay /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042903 // tubulin deacetylase activity // inferred from direct assay /// 0042903 // tubulin deacetylase activity // inferred from sequence or structural similarity /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 206847_s_at AF026397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026397.1 /DEF=Homo sapiens homeobox transcription factor HOXA7 (HOXA7) mRNA, complete cds. /FEA=mRNA /GEN=HOXA7 /PROD=homeobox transcription factor HOXA7 /DB_XREF=gi:2739070 /UG=Hs.70954 homeo box A7 /FL=gb:AF026397.1 gb:NM_006896.1 AF026397 homeobox A7 HOXA7 3204 NM_006896 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from expression pattern /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002686 // negative regulation of leukocyte migration // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from direct assay /// 0045656 // negative regulation of monocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 206848_at NM_006896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006896.1 /DEF=Homo sapiens homeo box A7 (HOXA7), mRNA. /FEA=mRNA /GEN=HOXA7 /PROD=homeo box A7 /DB_XREF=gi:5901971 /UG=Hs.70954 homeo box A7 /FL=gb:AF026397.1 gb:NM_006896.1 NM_006896 COX20 cytochrome C oxidase assembly factor COX20 116228 NM_198076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from expression pattern /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002686 // negative regulation of leukocyte migration // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from direct assay /// 0045656 // negative regulation of monocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206849_at NM_000816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000816.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), mRNA. /FEA=mRNA /GEN=GABRG2 /PROD=gamma-aminobutyric acid A receptor, gamma 2precursor /DB_XREF=gi:4557610 /UG=Hs.7195 gamma-aminobutyric acid (GABA) A receptor, gamma 2 /FL=gb:NM_000816.1 NM_000816 gamma-aminobutyric acid (GABA) A receptor, gamma 2 GABRG2 2566 NM_000816 /// NM_198903 /// NM_198904 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0051932 // synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from sequence or structural similarity /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060077 // inhibitory synapse // inferred from electronic annotation /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008503 // benzodiazepine receptor activity // traceable author statement 206850_at NM_006477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006477.1 /DEF=Homo sapiens RAS-related on chromsome 22 (RRP22), mRNA. /FEA=mRNA /GEN=RRP22 /PROD=RAS-related on chromsome 22 /DB_XREF=gi:5454029 /UG=Hs.73088 RAS-related on chromsome 22 /FL=gb:NM_006477.1 NM_006477 RAS-like, family 10, member A RASL10A 10633 NM_001007279 /// NM_006477 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 206851_at NM_002935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002935.1 /DEF=Homo sapiens ribonuclease, RNase A family, 3 (eosinophil cationic protein) (RNASE3), mRNA. /FEA=mRNA /GEN=RNASE3 /PROD=ribonuclease, RNase A family, 3 (eosinophilcationic protein) /DB_XREF=gi:4506550 /UG=Hs.73839 ribonuclease, RNase A family, 3 (eosinophil cationic protein) /FL=gb:NM_002935.1 gb:M28128.1 NM_002935 ribonuclease, RNase A family, 3 RNASE3 6037 NM_002935 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006401 // RNA catabolic process // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation 206852_at NM_004440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004440.1 /DEF=Homo sapiens EphA7 (EPHA7), mRNA. /FEA=mRNA /GEN=EPHA7 /PROD=EphA7 /DB_XREF=gi:4758281 /UG=Hs.73962 EphA7 /FL=gb:NM_004440.1 gb:L36642.1 NM_004440 EPH receptor A7 EPHA7 2045 NM_001288629 /// NM_001288630 /// NM_004440 /// XM_005248669 /// XM_005248671 /// XM_006715369 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0031952 // regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation 206853_s_at AL121964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121964 /DEF=Human DNA sequence from clone RP1-154G14 on chromosome 6q15-16.3. Contains the 3 end of the MAP3K7 gene for mitogen-activated protein kinase kinase kinase 7 (TGF-beta activated kinase 1, TAK1), ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:6996467 /UG=Hs.7510 mitogen-activated protein kinase kinase kinase 7 /FL=gb:AB009356.1 gb:NM_003188.1 AL121964 mitogen-activated protein kinase kinase kinase 7 MAP3K7 6885 NM_003188 /// NM_145331 /// NM_145332 /// NM_145333 /// XM_006715553 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from direct assay 206854_s_at NM_003188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003188.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 7 (MAP3K7), mRNA. /FEA=mRNA /GEN=MAP3K7 /PROD=mitogen-activated protein kinase kinase kinase7 /DB_XREF=gi:4507360 /UG=Hs.7510 mitogen-activated protein kinase kinase kinase 7 /FL=gb:AB009356.1 gb:NM_003188.1 NM_003188 mitogen-activated protein kinase kinase kinase 7 MAP3K7 6885 NM_003188 /// NM_145331 /// NM_145332 /// NM_145333 /// XM_006715553 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from direct assay 206855_s_at NM_003773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003773.1 /DEF=Homo sapiens hyaluronoglucosaminidase 2 (HYAL2), mRNA. /FEA=mRNA /GEN=HYAL2 /PROD=hyaluronoglucosaminidase 2 /DB_XREF=gi:4504550 /UG=Hs.76873 hyaluronoglucosaminidase 2 /FL=gb:U09577.1 gb:NM_003773.1 NM_003773 hyaluronoglucosaminidase 2 HYAL2 8692 NM_003773 /// NM_033158 /// XM_005265524 /// XM_005265525 0000302 // response to reactive oxygen species // inferred from direct assay /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010764 // negative regulation of fibroblast migration // inferred from direct assay /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0019087 // transformation of host cell by virus // inferred from direct assay /// 0019087 // transformation of host cell by virus // inferred from sequence or structural similarity /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0042117 // monocyte activation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046718 // viral entry into host cell // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0051216 // cartilage development // inferred from expression pattern /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070295 // renal water absorption // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071493 // cellular response to UV-B // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from direct assay /// 2000778 // positive regulation of interleukin-6 secretion // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0046658 // anchored component of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030294 // receptor signaling protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0033906 // hyaluronoglucuronidase activity // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity 206856_at NM_006840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006840.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 (LILRB5), mRNA. /FEA=mRNA /GEN=LILRB5 /PROD=leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains), member 5 /DB_XREF=gi:5803069 /UG=Hs.77062 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 /FL=gb:AF025534.1 gb:NM_006840.1 NM_006840 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 LILRB5 10990 NM_001081442 /// NM_001081443 /// NM_006840 /// XM_005258436 /// XM_005277049 /// XM_005277223 /// XM_005278239 /// XM_006722978 /// XM_006726144 /// XM_006726253 /// XM_006726254 /// XM_006726255 /// XM_006726256 /// XM_006726288 /// XM_006726289 /// XM_006726290 /// XM_006726291 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206857_s_at NM_004116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004116.1 /DEF=Homo sapiens FK506-binding protein 1B (12.6 kD) (FKBP1B), mRNA. /FEA=mRNA /GEN=FKBP1B /PROD=FK506-binding protein 1B (12.6 kD) /DB_XREF=gi:4758379 /UG=Hs.77643 FK506-binding protein 1B (12.6 kD) /FL=gb:NM_004116.1 gb:D38037.1 gb:L37086.1 NM_004116 FK506 binding protein 1B, 12.6 kDa FKBP1B 2281 NM_004116 /// NM_054033 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // traceable author statement /// 0006936 // muscle contraction // non-traceable author statement /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // not recorded /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030073 // insulin secretion // inferred from electronic annotation /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0048680 // positive regulation of axon regeneration // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051284 // positive regulation of sequestering of calcium ion // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from genetic interaction /// 0051775 // response to redox state // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from mutant phenotype /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // not recorded /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // not recorded /// 0034704 // calcium channel complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0030551 // cyclic nucleotide binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from sequence or structural similarity 206858_s_at NM_004503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004503.1 /DEF=Homo sapiens homeo box C6 (HOXC6), mRNA. /FEA=mRNA /GEN=HOXC6 /PROD=homeo box C6 /DB_XREF=gi:4758553 /UG=Hs.820 homeo box C6 /FL=gb:NM_004503.1 NM_004503 homeobox C6 HOXC6 3223 NM_004503 /// NM_153693 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206859_s_at NM_002571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002571.1 /DEF=Homo sapiens progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein) (PAEP), mRNA. /FEA=mRNA /GEN=PAEP /PROD=progestagen-associated endometrial protein(placental protein 14, pregnancy-associated endometrialalpha-2-globulin, alpha uterine protein) /DB_XREF=gi:4505582 /UG=Hs.82269 progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein) /FL=gb:J04129.1 gb:NM_002571.1 NM_002571 progestagen-associated endometrial protein PAEP 5047 NM_001018049 /// NM_002571 /// XM_005263405 /// XM_005263406 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0036094 // small molecule binding // inferred from electronic annotation 206860_s_at NM_019005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019005.1 /DEF=Homo sapiens hypothetical protein (FLJ20323), mRNA. /FEA=mRNA /GEN=FLJ20323 /PROD=hypothetical protein /DB_XREF=gi:9506672 /UG=Hs.83937 hypothetical protein /FL=gb:NM_019005.1 NM_019005 missing oocyte, meiosis regulator, homolog (Drosophila) MIOS 54468 NM_019005 /// XM_005249780 /// XM_005249781 /// XM_005249782 /// XM_005249783 /// XM_005249784 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 206861_s_at NM_003663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003663.1 /DEF=Homo sapiens CGG triplet repeat binding protein 1 (CGGBP1), mRNA. /FEA=mRNA /GEN=CGGBP1 /PROD=CGG triplet repeat binding protein 1 /DB_XREF=gi:4502790 /UG=Hs.86041 CGG triplet repeat binding protein 1 /FL=gb:NM_003663.1 NM_003663 CGG triplet repeat binding protein 1 CGGBP1 8545 NM_001008390 /// NM_001195308 /// NM_003663 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement 206862_at NM_004876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004876.1 /DEF=Homo sapiens zinc finger protein 254 (ZNF254), mRNA. /FEA=mRNA /GEN=ZNF254 /PROD=zinc finger protein 254 /DB_XREF=gi:4758513 /UG=Hs.86371 zinc finger protein 254 /FL=gb:AF054180.1 gb:NM_004876.1 NM_004876 zinc finger protein 254 ZNF254 9534 NM_001278661 /// NM_001278662 /// NM_001278663 /// NM_001278664 /// NM_001278665 /// NM_001278677 /// NM_001278678 /// NM_004876 /// NM_203282 /// XM_005260166 /// XM_005260167 /// XM_005260168 /// XM_005260169 /// XM_006722948 /// XM_006722949 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206863_x_at U76376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U76376.1 /DEF=Homo sapiens activator of apoptosis Hrk (HRK) mRNA, complete cds. /FEA=mRNA /GEN=HRK /PROD=activator of apoptosis Hrk /DB_XREF=gi:1923234 /UG=Hs.87247 harakiri, BCL2-interacting protein (contains only BH3 domain) /FL=gb:U76376.1 gb:NM_003806.1 U76376 206864_s_at NM_003806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003806.1 /DEF=Homo sapiens harakiri, BCL2-interacting protein (contains only BH3 domain) (HRK), mRNA. /FEA=mRNA /GEN=HRK /PROD=harakiri /DB_XREF=gi:4504492 /UG=Hs.87247 harakiri, BCL2-interacting protein (contains only BH3 domain) /FL=gb:U76376.1 gb:NM_003806.1 NM_003806 harakiri, BCL2 interacting protein HRK 8739 NM_003806 /// NR_073189 0006915 // apoptotic process // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206865_at U76376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U76376.1 /DEF=Homo sapiens activator of apoptosis Hrk (HRK) mRNA, complete cds. /FEA=mRNA /GEN=HRK /PROD=activator of apoptosis Hrk /DB_XREF=gi:1923234 /UG=Hs.87247 harakiri, BCL2-interacting protein (contains only BH3 domain) /FL=gb:U76376.1 gb:NM_003806.1 U76376 harakiri, BCL2 interacting protein HRK 8739 NM_003806 /// NR_073189 0006915 // apoptotic process // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206866_at NM_001794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001794.1 /DEF=Homo sapiens cadherin 4, type 1, R-cadherin (retinal) (CDH4), mRNA. /FEA=mRNA /GEN=CDH4 /PROD=cadherin 4, type 1, R-cadherin (retinal) /DB_XREF=gi:4502724 /UG=Hs.89484 cadherin 4, type 1, R-cadherin (retinal) /FL=gb:NM_001794.1 gb:L34059.1 NM_001794 cadherin 4, type 1, R-cadherin (retinal) CDH4 1002 NM_001252338 /// NM_001252339 /// NM_001794 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206867_at NM_001486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001486.1 /DEF=Homo sapiens glucokinase (hexokinase 4) regulatory protein (GCKR), mRNA. /FEA=mRNA /GEN=GCKR /PROD=glucokinase regulatory protein /DB_XREF=gi:4557620 /UG=Hs.89771 glucokinase (hexokinase 4) regulatory protein /FL=gb:NM_001486.1 NM_001486 glucokinase (hexokinase 4) regulator GCKR 2646 NM_001486 /// XM_005264256 /// XM_005264257 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0009750 // response to fructose // inferred from direct assay /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from direct assay /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0070095 // fructose-6-phosphate binding // inferred from direct assay 206868_at NM_014725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014725.1 /DEF=Homo sapiens KIAA0189 gene product (KIAA0189), mRNA. /FEA=mRNA /GEN=KIAA0189 /PROD=KIAA0189 gene product /DB_XREF=gi:7661981 /UG=Hs.95140 KIAA0189 gene product /FL=gb:D80011.1 gb:NM_014725.1 NM_014725 StAR-related lipid transfer (START) domain containing 8 STARD8 9754 NM_001142503 /// NM_001142504 /// NM_014725 /// XM_005262314 /// XM_005262315 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 206869_at NM_001267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001267.1 /DEF=Homo sapiens chondroadherin (CHAD), mRNA. /FEA=mRNA /GEN=CHAD /PROD=chondroadherin precursor /DB_XREF=gi:4502798 /UG=Hs.97220 chondroadherin /FL=gb:NM_001267.1 NM_001267 chondroadherin CHAD 1101 NM_001267 0001502 // cartilage condensation // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 206870_at NM_005036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005036.2 /DEF=Homo sapiens peroxisome proliferative activated receptor, alpha (PPARA), mRNA. /FEA=mRNA /GEN=PPARA /PROD=peroxisome proliferative activated receptor,alpha /DB_XREF=gi:7549810 /UG=Hs.998 peroxisome proliferative activated receptor, alpha /FL=gb:L02932.1 gb:NM_005036.2 NM_005036 peroxisome proliferator-activated receptor alpha PPARA 5465 NM_001001928 /// NM_001001929 /// NM_001001930 /// NM_005036 /// NM_032644 /// XM_005261653 /// XM_005261655 /// XM_005261656 /// XM_005261657 /// XM_006724269 /// XM_006724270 /// XM_006724271 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010871 // negative regulation of receptor biosynthetic process // inferred from direct assay /// 0010887 // negative regulation of cholesterol storage // inferred from direct assay /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0015908 // fatty acid transport // traceable author statement /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035095 // behavioral response to nicotine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046321 // positive regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation /// 0072363 // regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072366 // regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0019902 // phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from electronic annotation /// 0097371 // MDM2/MDM4 family protein binding // inferred from electronic annotation 206871_at NM_001972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001972.1 /DEF=Homo sapiens elastase 2, neutrophil (ELA2), mRNA. /FEA=mRNA /GEN=ELA2 /PROD=elastase 2, neutrophil /DB_XREF=gi:4503548 /UG=Hs.99863 elastase 2, neutrophil /FL=gb:M34379.1 gb:NM_001972.1 NM_001972 elastase, neutrophil expressed ELANE 1991 NM_001972 /// XM_005259517 /// XM_006725397 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001878 // response to yeast // inferred from electronic annotation /// 0002438 // acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // non-traceable author statement /// 0006909 // phagocytosis // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030163 // protein catabolic process // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // non-traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045079 // negative regulation of chemokine biosynthetic process // inferred from direct assay /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // non-traceable author statement /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0050922 // negative regulation of chemotaxis // non-traceable author statement /// 0070947 // neutrophil mediated killing of fungus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from mutant phenotype /// 0002020 // protease binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from physical interaction 206872_at NM_005074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005074.1 /DEF=Homo sapiens solute carrier family 17 (sodium phosphate), member 1 (SLC17A1), mRNA. /FEA=mRNA /GEN=SLC17A1 /PROD=solute carrier family 17 (sodium phosphate),member 1 /DB_XREF=gi:4827009 /UG=Hs.100001 solute carrier family 17 (sodium phosphate), member 1 /FL=gb:NM_005074.1 gb:D28532.1 NM_005074 solute carrier family 17 (organic anion transporter), member 1 SLC17A1 6568 NM_005074 /// XM_005249306 /// XM_005249307 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // traceable author statement /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0015114 // phosphate ion transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // traceable author statement 206873_at NM_001215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001215.1 /DEF=Homo sapiens carbonic anhydrase VI (CA6), mRNA. /FEA=mRNA /GEN=CA6 /PROD=carbonic anhydrase VI precursor /DB_XREF=gi:4557396 /UG=Hs.100322 carbonic anhydrase VI /FL=gb:M57892.1 gb:NM_001215.1 NM_001215 carbonic anhydrase VI CA6 765 NM_001215 /// NM_001270500 /// NM_001270501 /// NM_001270502 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206874_s_at AL138761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL138761 /DEF=Human DNA sequence from clone RP11-16H23 on chromosome 10. Contains the gene KIAA0204 (HSLK) for a protein kinase, the COL17A1 gene for collagen type XVII alpha 1 (BP180), ESTs and GSSs /FEA=mRNA_2 /DB_XREF=gi:8573811 /UG=Hs.105751 Ste20-related serinethreonine kinase /FL=gb:D86959.1 gb:NM_014720.1 AL138761 STE20-like kinase SLK 9748 NM_014720 /// XM_005270301 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 206875_s_at NM_014720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014720.1 /DEF=Homo sapiens Ste20-related serinethreonine kinase (KIAA0204), mRNA. /FEA=mRNA /GEN=KIAA0204 /PROD=Ste20-related serinethreonine kinase /DB_XREF=gi:7661993 /UG=Hs.105751 Ste20-related serinethreonine kinase /FL=gb:D86959.1 gb:NM_014720.1 NM_014720 STE20-like kinase SLK 9748 NM_014720 /// XM_005270301 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 206876_at AL121948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121948 /DEF=Human DNA sequence from clone RP3-399E4 on chromosome 6. Contains the 3 end of the SIM1 gene for single-minded (Drosophila) homolog 1, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:7981300 /UG=Hs.105925 single-minded (Drosophila) homolog 1 /FL=gb:U70212.1 gb:NM_005068.1 AL121948 single-minded family bHLH transcription factor 1 SIM1 6492 NM_005068 /// XM_005267100 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 206877_at NM_002357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002357.1 /DEF=Homo sapiens MAX dimerization protein (MAD), mRNA. /FEA=mRNA /GEN=MAD /PROD=MAX dimerization protein /DB_XREF=gi:4505068 /UG=Hs.109012 MAX dimerization protein /FL=gb:L06895.1 gb:NM_002357.1 NM_002357 MAX dimerization protein 1 MXD1 4084 NM_001202513 /// NM_001202514 /// NM_002357 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 206878_at NM_001917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001917.1 /DEF=Homo sapiens D-amino-acid oxidase (DAO), mRNA. /FEA=mRNA /GEN=DAO /PROD=D-amino-acid oxidase /DB_XREF=gi:4503254 /UG=Hs.113227 D-amino-acid oxidase /FL=gb:NM_001917.1 NM_001917 D-amino-acid oxidase DAO 1610 NM_001917 /// XM_005268692 /// XM_006719268 /// XM_006719269 0006551 // leucine metabolic process // inferred from electronic annotation /// 0006562 // proline catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0036088 // D-serine catabolic process // inferred from direct assay /// 0042416 // dopamine biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055130 // D-alanine catabolic process // inferred from direct assay /// 0070178 // D-serine metabolic process // inferred from direct assay 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay 0003884 // D-amino-acid oxidase activity // inferred from direct assay /// 0003884 // D-amino-acid oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0071949 // FAD binding // inferred from direct assay 206879_s_at NM_013982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013982.1 /DEF=Homo sapiens neuregulin 2 (NRG2), transcript variant 3, mRNA. /FEA=mRNA /GEN=NRG2 /PROD=neuregulin 2 isoform 3 /DB_XREF=gi:7669529 /UG=Hs.113264 neuregulin 2 /FL=gb:NM_013982.1 NM_013982 neuregulin 2 NRG2 9542 NM_001184935 /// NM_004883 /// NM_013981 /// NM_013982 /// NM_013983 /// NM_013984 /// NM_013985 /// XM_005268533 /// XM_006714808 /// XM_006714809 /// XM_006714810 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 206880_at NM_005446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005446.1 /DEF=Homo sapiens purinergic receptor P2X-like 1, orphan receptor (P2RXL1), mRNA. /FEA=mRNA /GEN=P2RXL1 /PROD=purinergic receptor P2X-like 1, orphan receptor /DB_XREF=gi:4885534 /UG=Hs.113275 purinergic receptor P2X-like 1, orphan receptor /FL=gb:AB002058.1 gb:NM_005446.1 NM_005446 purinergic receptor P2X, ligand-gated ion channel, 6 P2RX6 9127 NM_001159554 /// NM_005446 /// XM_005261819 /// XM_006724369 /// XM_006724370 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // not recorded /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005639 // integral component of nuclear inner membrane // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0015267 // channel activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 206881_s_at NM_006865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006865.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 (LILRA3), mRNA. /FEA=mRNA /GEN=LILRA3 /PROD=leukocyte immunoglobulin-like receptor,subfamily A (without TM domain), member 3 /DB_XREF=gi:5803061 /UG=Hs.113277 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 /FL=gb:U91926.1 gb:AF025527.1 gb:AF014923.1 gb:NM_006865.1 NM_006865 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 LILRA3 11026 NM_001172654 /// NM_006865 /// XM_005277092 /// XM_006710242 /// XM_006726167 /// XM_006726168 /// XM_006726169 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement 206882_at NM_005071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005071.1 /DEF=Homo sapiens solute carrier family 1 (high affinity aspartateglutamate transporter), member 6 (SLC1A6), mRNA. /FEA=mRNA /GEN=SLC1A6 /PROD=solute carrier family 1 (high affinityaspartateglutamate transporter), member 6 /DB_XREF=gi:4827011 /UG=Hs.113602 solute carrier family 1 (high affinity aspartateglutamate transporter), member 6 /FL=gb:NM_005071.1 gb:U18244.1 NM_005071 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 SLC1A6 6511 NM_001272087 /// NM_001272088 /// NM_005071 /// NR_073589 /// XM_006722842 /// XM_006722843 /// XM_006722844 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015810 // aspartate transport // traceable author statement /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from electronic annotation /// 0015183 // L-aspartate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 206883_x_at NM_000174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000174.1 /DEF=Homo sapiens glycoprotein IX (platelet) (GP9), mRNA. /FEA=mRNA /GEN=GP9 /PROD=glycoprotein IX (platelet) /DB_XREF=gi:4504076 /UG=Hs.1144 glycoprotein IX (platelet) /FL=gb:NM_000174.1 NM_000174 glycoprotein IX (platelet) GP9 2815 NM_000174 /// XM_005247374 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 206884_s_at NM_003843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003843.1 /DEF=Homo sapiens sciellin (SCEL), mRNA. /FEA=mRNA /GEN=SCEL /PROD=sciellin /DB_XREF=gi:4506798 /UG=Hs.115166 sciellin /FL=gb:AF045941.1 gb:NM_003843.1 NM_003843 sciellin SCEL 8796 NM_001160706 /// NM_003843 /// NM_144777 /// XM_005266578 /// XM_006719882 /// XM_006719883 /// XM_006719884 /// XM_006719885 /// XM_006719886 0008544 // epidermis development // inferred from sequence or structural similarity /// 0008544 // epidermis development // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from direct assay 0001533 // cornified envelope // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206885_x_at NM_022559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022559.1 /DEF=Homo sapiens growth hormone 1 (GH1), transcript variant 2, mRNA. /FEA=mRNA /GEN=GH1 /PROD=growth hormone 1, isoform 2 precursor /DB_XREF=gi:13027813 /UG=Hs.115352 growth hormone 1 /FL=gb:NM_022559.1 NM_022559 growth hormone 1 GH1 2688 NM_000515 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206886_x_at NM_022560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022560.1 /DEF=Homo sapiens growth hormone 1 (GH1), transcript variant 3, mRNA. /FEA=mRNA /GEN=GH1 /PROD=growth hormone 1, isoform 3 precursor /DB_XREF=gi:13027815 /UG=Hs.115352 growth hormone 1 /FL=gb:NM_022560.1 NM_022560 growth hormone 1 GH1 2688 NM_000515 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206887_at NM_001296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001296.1 /DEF=Homo sapiens chemokine binding protein 2 (CCBP2), mRNA. /FEA=mRNA /GEN=CCBP2 /PROD=chemokine binding protein 2 /DB_XREF=gi:4502910 /UG=Hs.117572 chemokine binding protein 2 /FL=gb:U94888.1 gb:NM_001296.1 NM_001296 atypical chemokine receptor 2 ACKR2 1238 NM_001296 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0042119 // neutrophil activation // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation /// 0019957 // C-C chemokine binding // inferred from electronic annotation 206888_s_at U82532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82532.1 /DEF=Homo sapiens GDI-dissociation inhibitor RhoGDIgamma mRNA, complete cds. /FEA=mRNA /PROD=GDI-dissociation inhibitor RhoGDIgamma /DB_XREF=gi:1772912 /UG=Hs.121516 Rho GDP dissociation inhibitor (GDI) gamma /FL=gb:U82532.1 gb:NM_001176.1 U82532 Rho GDP dissociation inhibitor (GDI) gamma ARHGDIG 398 NM_001176 0006457 // protein folding // /// 0006457 // protein folding // traceable author statement /// 0006621 // protein retention in ER lumen // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0019511 // peptidyl-proline hydroxylation // /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement 0003756 // protein disulfide isomerase activity // /// 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0003756 // protein disulfide isomerase activity // traceable author statement /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // 206889_at NM_001176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001176.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) gamma (ARHGDIG), mRNA. /FEA=mRNA /GEN=ARHGDIG /PROD=Rho GDP dissociation inhibitor (GDI) gamma /DB_XREF=gi:4502224 /UG=Hs.121516 Rho GDP dissociation inhibitor (GDI) gamma /FL=gb:U82532.1 gb:NM_001176.1 NM_001176 protein disulfide isomerase family A, member 2 PDIA2 64714 NM_006849 0006457 // protein folding // not recorded /// 0006621 // protein retention in ER lumen // traceable author statement /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // not recorded /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement 0003756 // protein disulfide isomerase activity // not recorded /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005094 // Rho GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // not recorded 206890_at NM_005535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005535.1 /DEF=Homo sapiens interleukin 12 receptor, beta 1 (IL12RB1), mRNA. /FEA=mRNA /GEN=IL12RB1 /PROD=interleukin 12 receptor, beta 1 /DB_XREF=gi:5031784 /UG=Hs.121544 interleukin 12 receptor, beta 1 /FL=gb:NM_005535.1 gb:U03187.1 NM_005535 interleukin 12 receptor, beta 1 IL12RB1 3594 NM_001290023 /// NM_001290024 /// NM_005535 /// NM_153701 /// XM_005259893 /// XM_006722741 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred by curator /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0038155 // interleukin-23-mediated signaling pathway // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042022 // interleukin-12 receptor complex // inferred from direct assay /// 0072536 // interleukin-23 receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // traceable author statement /// 0005143 // interleukin-12 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016517 // interleukin-12 receptor activity // inferred from direct assay /// 0019955 // cytokine binding // inferred from electronic annotation /// 0042019 // interleukin-23 binding // inferred from physical interaction /// 0042020 // interleukin-23 receptor activity // inferred from direct assay 206891_at NM_001104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001104.1 /DEF=Homo sapiens actinin, alpha 3 (ACTN3), mRNA. /FEA=mRNA /GEN=ACTN3 /PROD=skeletal muscle specific actinin, alpha 3 /DB_XREF=gi:4557240 /UG=Hs.1216 actinin, alpha 3 /FL=gb:M86407.1 gb:NM_001104.1 NM_001104 actinin, alpha 3 ACTN3 89 NM_001104 /// NM_001258371 /// NR_047663 0030049 // muscle filament sliding // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0031143 // pseudopodium // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206892_at NM_020547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020547.1 /DEF=Homo sapiens anti-Mullerian hormone receptor, type II (AMHR2), mRNA. /FEA=mRNA /GEN=AMHR2 /PROD=anti-Mullerian hormone receptor, type II /DB_XREF=gi:10198655 /UG=Hs.123014 anti-Mullerian hormone receptor, type II /FL=gb:NM_020547.1 gb:AF172932.1 NM_020547 anti-Mullerian hormone receptor, type II AMHR2 269 NM_001164690 /// NM_001164691 /// NM_020547 /// XM_005268786 /// XM_005268787 /// XM_005268788 /// XM_005268789 /// XM_005268790 /// XM_005268791 /// XM_005268792 /// XM_005268793 /// XM_005268794 /// XM_005268795 0001880 // Mullerian duct regression // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from sequence or structural similarity /// 0007548 // sex differentiation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005026 // transforming growth factor beta receptor activity, type II // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 206893_at NM_002968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002968.1 /DEF=Homo sapiens sal (Drosophila)-like 1 (SALL1), mRNA. /FEA=mRNA /GEN=SALL1 /PROD=sal (Drosophila)-like 1 /DB_XREF=gi:6997248 /UG=Hs.123094 sal (Drosophila)-like 1 /FL=gb:NM_002968.1 NM_002968 spalt-like transcription factor 1 SALL1 6299 NM_001127892 /// NM_002968 /// XM_006721241 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0008406 // gonad development // inferred from expression pattern /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0021553 // olfactory nerve development // inferred from sequence or structural similarity /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021889 // olfactory bulb interneuron differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from expression pattern /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030325 // adrenal gland development // inferred from expression pattern /// 0031129 // inductive cell-cell signaling // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from mutant phenotype /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0060173 // limb development // inferred from mutant phenotype /// 0061034 // olfactory bulb mitral cell layer development // inferred from mutant phenotype /// 0072073 // kidney epithelium development // inferred from sequence or structural similarity /// 0072092 // ureteric bud invasion // inferred from sequence or structural similarity /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0000792 // heterochromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010369 // chromocenter // inferred from direct assay /// 0016581 // NuRD complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004407 // histone deacetylase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206894_at NM_000482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000482.2 /DEF=Homo sapiens apolipoprotein A-IV (APOA4), mRNA. /FEA=mRNA /GEN=APOA4 /PROD=apolipoprotein A-IV precursor /DB_XREF=gi:5174773 /UG=Hs.1247 apolipoprotein A-IV /FL=gb:NM_000482.2 NM_000482 apolipoprotein A-IV APOA4 337 NM_000482 0001523 // retinoid metabolic process // traceable author statement /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from direct assay /// 0006982 // response to lipid hydroperoxide // inferred from direct assay /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0032374 // regulation of cholesterol transport // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred by curator /// 0034378 // chylomicron assembly // traceable author statement /// 0034445 // negative regulation of plasma lipoprotein particle oxidation // inferred from direct assay /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044240 // multicellular organismal lipid catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from direct assay /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from direct assay /// 0065005 // protein-lipid complex assembly // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005319 // lipid transporter activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0008289 // lipid binding // inferred from mutant phenotype /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay 206895_at NM_002711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002711.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 3 (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle) (PPP1R3), mRNA. /FEA=mRNA /GEN=PPP1R3 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 3 (glycogen and sarcoplasmic reticulum bindingsubunit, skeletal muscle) /DB_XREF=gi:4506010 /UG=Hs.127614 protein phosphatase 1, regulatory (inhibitor) subunit 3 (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle) /FL=gb:NM_002711.1 NM_002711 protein phosphatase 1, regulatory subunit 3A PPP1R3A 5506 NM_002711 /// XM_005250473 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206896_s_at NM_005145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005145.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), gamma 7 (GNG7), mRNA. /FEA=mRNA /GEN=GNG7 /PROD=guanine nucleotide binding protein (G protein),gamma 7 /DB_XREF=gi:4826745 /UG=Hs.127828 guanine nucleotide binding protein (G protein), gamma 7 /FL=gb:AB010414.1 gb:NM_005145.1 NM_005145 guanine nucleotide binding protein (G protein), gamma 7 GNG7 2788 NM_052847 0001662 // behavioral fear response // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045761 // regulation of adenylate cyclase activity // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation 206897_at NM_003785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003785.2 /DEF=Homo sapiens G antigen, family B, 1 (prostate associated) (GAGEB1), mRNA. /FEA=mRNA /GEN=GAGEB1 /PROD=G antigen B1 /DB_XREF=gi:9558760 /UG=Hs.128231 G antigen, family B, 1 (prostate associated) /FL=gb:BC004861.1 gb:AF058989.1 gb:NM_003785.2 NM_003785 P antigen family, member 1 (prostate associated) PAGE1 8712 NM_003785 0006968 // cellular defense response // traceable author statement 206898_at NM_021153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021153.1 /DEF=Homo sapiens cadherin 19, type 2 (CDH19), mRNA. /FEA=mRNA /GEN=CDH19 /PROD=cadherin 19, type 2 /DB_XREF=gi:12656654 /UG=Hs.129887 cadherin 19, type 2 /FL=gb:NM_021153.1 NM_021153 cadherin 19, type 2 CDH19 28513 NM_001271028 /// NM_021153 /// NR_073130 /// XM_006722440 /// XM_006722441 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206899_at NM_012344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012344.1 /DEF=Homo sapiens neurotensin receptor 2 (NTSR2), mRNA. /FEA=mRNA /GEN=NTSR2 /PROD=neurotensin receptor 2 /DB_XREF=gi:6912537 /UG=Hs.131138 neurotensin receptor 2 /FL=gb:NM_012344.1 NM_012344 neurotensin receptor 2 NTSR2 23620 NM_012344 /// XM_005246156 /// XM_006711876 /// XM_006711877 /// XM_006711878 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007600 // sensory perception // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0016492 // G-protein coupled neurotensin receptor activity // inferred from electronic annotation 206900_x_at NM_021047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021047.1 /DEF=Homo sapiens DNA-binding protein (LOC56242), mRNA. /FEA=mRNA /GEN=LOC56242 /PROD=DNA-binding protein /DB_XREF=gi:10567821 /UG=Hs.137582 DNA-binding protein /FL=gb:NM_021047.1 gb:AF038951.1 NM_021047 zinc finger protein 253 ZNF253 56242 NM_021047 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206901_at NM_024323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024323.1 /DEF=Homo sapiens hypothetical protein MGC11271 (MGC11271), mRNA. /FEA=mRNA /GEN=MGC11271 /PROD=hypothetical protein MGC11271 /DB_XREF=gi:13236566 /UG=Hs.143288 hypothetical protein MGC11271 /FL=gb:BC002891.1 gb:NM_024323.1 NM_024323 chromosome 19 open reading frame 57 C19orf57 79173 NM_024323 /// XM_005260078 /// XM_006722885 0007275 // multicellular organismal development // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 206902_s_at NM_005728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005728.1 /DEF=Homo sapiens endonuclease G-like 2 (ENDOGL2), mRNA. /FEA=mRNA /GEN=ENDOGL2 /PROD=endonuclease G-like 2 /DB_XREF=gi:5031686 /UG=Hs.145515 endonuclease G-like 2 /FL=gb:AB020735.1 gb:NM_005728.1 NM_005728 endo/exonuclease (5'-3'), endonuclease G-like EXOG 9941 NM_001145464 /// NM_005107 /// XM_005265633 /// XM_005265635 /// XM_006713442 /// XM_006713443 /// XM_006713444 /// XM_006713445 /// XM_006713446 /// XM_006713447 0000737 // DNA catabolic process, endonucleolytic // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206903_at NM_005728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005728.1 /DEF=Homo sapiens endonuclease G-like 2 (ENDOGL2), mRNA. /FEA=mRNA /GEN=ENDOGL2 /PROD=endonuclease G-like 2 /DB_XREF=gi:5031686 /UG=Hs.145515 endonuclease G-like 2 /FL=gb:AB020735.1 gb:NM_005728.1 NM_005728 endo/exonuclease (5'-3'), endonuclease G-like EXOG 9941 NM_001145464 /// NM_005107 /// XM_005265633 /// XM_005265635 /// XM_006713442 /// XM_006713443 /// XM_006713444 /// XM_006713445 /// XM_006713446 /// XM_006713447 0000737 // DNA catabolic process, endonucleolytic // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206904_at M55683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M55683.1 /DEF=Human cartilage matrix protein (CMP) mRNA, exons 3-8. /FEA=mRNA /GEN=CRTM /PROD=cartilage matrix protein /DB_XREF=gi:180651 /UG=Hs.150366 matrilin 1, cartilage matrix protein /FL=gb:NM_002379.2 M55683 matrilin 1, cartilage matrix protein MATN1 4146 NM_002379 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003429 // growth plate cartilage chondrocyte morphogenesis // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030500 // regulation of bone mineralization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206905_s_at NM_002379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002379.2 /DEF=Homo sapiens matrilin 1, cartilage matrix protein (MATN1), mRNA. /FEA=mRNA /GEN=MATN1 /PROD=matrilin 1, cartilage matrix protein /DB_XREF=gi:13518035 /UG=Hs.150366 matrilin 1, cartilage matrix protein /FL=gb:NM_002379.2 NM_002379 matrilin 1, cartilage matrix protein MATN1 4146 NM_002379 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003429 // growth plate cartilage chondrocyte morphogenesis // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030500 // regulation of bone mineralization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206906_at NM_003259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003259.2 /DEF=Homo sapiens intercellular adhesion molecule 5, telencephalin (ICAM5), mRNA. /FEA=mRNA /GEN=ICAM5 /PROD=intercellular adhesion molecule 5 precursor /DB_XREF=gi:12545403 /UG=Hs.151250 intercellular adhesion molecule 5, telencephalin /FL=gb:NM_003259.2 gb:U72671.1 NM_003259 intercellular adhesion molecule 5, telencephalin ICAM5 7087 NM_003259 0006909 // phagocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 206907_at NM_003811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003811.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 9 (TNFSF9), mRNA. /FEA=mRNA /GEN=TNFSF9 /PROD=tumor necrosis factor (ligand) superfamily,member 9 /DB_XREF=gi:4507608 /UG=Hs.1524 tumor necrosis factor (ligand) superfamily, member 9 /FL=gb:NM_003811.1 gb:U03398.1 NM_003811 tumor necrosis factor (ligand) superfamily, member 9 TNFSF9 8744 NM_003811 /// XM_006722931 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0045585 // positive regulation of cytotoxic T cell differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation 206908_s_at NM_005602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005602.3 /DEF=Homo sapiens claudin 11 (oligodendrocyte transmembrane protein) (CLDN11), mRNA. /FEA=mRNA /GEN=CLDN11 /PROD=oligodendrocyte transmembrane protein /DB_XREF=gi:13518028 /UG=Hs.153297 claudin 11 (oligodendrocyte transmembrane protein) /FL=gb:NM_005602.3 gb:AF068863.1 NM_005602 claudin 11 CLDN11 5010 NM_001185056 /// NM_005602 0007155 // cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 206909_at AF068863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068863.1 /DEF=Homo sapiens oligodendrocyte-specific protein (OSP) mRNA, complete cds. /FEA=mRNA /GEN=OSP /PROD=oligodendrocyte-specific protein /DB_XREF=gi:3283414 /UG=Hs.153297 claudin 11 (oligodendrocyte transmembrane protein) /FL=gb:NM_005602.3 gb:AF068863.1 AF068863 0007155 // cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 206910_x_at NM_005666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005666.1 /DEF=Homo sapiens H factor (complement)-like 3 (HFL3), mRNA. /FEA=mRNA /GEN=HFL3 /PROD=H factor (complement)-like 3 /DB_XREF=gi:5031694 /UG=Hs.154224 H factor (complement)-like 3 /FL=gb:NM_005666.1 NM_005666 complement factor H-related 2 CFHR2 3080 NM_005666 /// XM_005245113 /// XM_006711285 0005576 // extracellular region // inferred from electronic annotation 206911_at NM_005082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005082.1 /DEF=Homo sapiens zinc finger protein 147 (estrogen-responsive finger protein) (ZNF147), mRNA. /FEA=mRNA /GEN=ZNF147 /PROD=zinc finger protein 147 (estrogen-responsivefinger protein) /DB_XREF=gi:4827064 /UG=Hs.1579 zinc finger protein 147 (estrogen-responsive finger protein) /FL=gb:D21205.1 gb:NM_005082.1 NM_005082 tripartite motif containing 25 TRIM25 7706 NM_005082 0002376 // immune system process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046596 // regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206912_at NM_004473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004473.2 /DEF=Homo sapiens forkhead box E1 (thyroid transcription factor 2) (FOXE1), mRNA. /FEA=mRNA /GEN=FOXE1 /PROD=forkhead box E1 /DB_XREF=gi:9257220 /UG=Hs.159234 forkhead box E1 (thyroid transcription factor 2) /FL=gb:U89995.1 gb:NM_004473.2 NM_004473 forkhead box E1 (thyroid transcription factor 2) FOXE1 2304 NM_004473 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006590 // thyroid hormone generation // not recorded /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0007389 // pattern specification process // not recorded /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // not recorded /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048538 // thymus development // inferred from expression pattern /// 0048562 // embryonic organ morphogenesis // not recorded /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0060022 // hard palate development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype /// 0060465 // pharynx development // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206913_at NM_001701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001701.1 /DEF=Homo sapiens bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) (BAAT), mRNA. /FEA=mRNA /GEN=BAAT /PROD=bile acid Coenzyme A: amino acidN-acyltransferase /DB_XREF=gi:4502350 /UG=Hs.159440 bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) /FL=gb:NM_001701.1 gb:L34081.1 NM_001701 bile acid CoA:amino acid N-acyltransferase BAAT 570 NM_001127610 /// NM_001701 0001889 // liver development // inferred from electronic annotation /// 0002152 // bile acid conjugation // inferred from direct assay /// 0006544 // glycine metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0019530 // taurine metabolic process // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from electronic annotation /// 0016410 // N-acyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // inferred from electronic annotation /// 0047963 // glycine N-choloyltransferase activity // inferred from direct assay /// 0052815 // medium-chain acyl-CoA hydrolase activity // inferred from direct assay /// 0052816 // long-chain acyl-CoA hydrolase activity // inferred from direct assay /// 0052817 // very long chain acyl-CoA hydrolase activity // inferred from direct assay 206914_at NM_019604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019604.1 /DEF=Homo sapiens class-I MHC-restricted T cell associated molecule (CRTAM), mRNA. /FEA=mRNA /GEN=CRTAM /PROD=class-I MHC-restricted T cell associatedmolecule /DB_XREF=gi:9624976 /UG=Hs.159523 class-I MHC-restricted T cell associated molecule /FL=gb:AF001622.1 gb:NM_019604.1 NM_019604 cytotoxic and regulatory T cell molecule CRTAM 56253 NM_019604 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002355 // detection of tumor cell // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from direct assay /// 0008037 // cell recognition // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050798 // activated T cell proliferation // inferred from direct assay /// 0051606 // detection of stimulus // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 206915_at NM_002509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002509.1 /DEF=Homo sapiens NK-2 (Drosophila) homolog B (NKX2B), mRNA. /FEA=mRNA /GEN=NKX2B /PROD=NK-2 (Drosophila) homolog B /DB_XREF=gi:4505400 /UG=Hs.159623 NK-2 (Drosophila) homolog B /FL=gb:NM_002509.1 NM_002509 NK2 homeobox 2 NKX2-2 4821 NM_002509 /// XM_006723566 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0003326 // pancreatic A cell fate commitment // inferred from electronic annotation /// 0003327 // type B pancreatic cell fate commitment // inferred from electronic annotation /// 0003329 // pancreatic PP cell fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021554 // optic nerve development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0032570 // response to progesterone // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048708 // astrocyte differentiation // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0060580 // ventral spinal cord interneuron fate determination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0001159 // core promoter proximal region DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206916_x_at NM_000353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000353.1 /DEF=Homo sapiens tyrosine aminotransferase (TAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=TAT /PROD=tyrosine aminotransferase /DB_XREF=gi:4507368 /UG=Hs.161640 tyrosine aminotransferase /FL=gb:NM_000353.1 NM_000353 tyrosine aminotransferase TAT 6898 NM_000353 0006103 // 2-oxoglutarate metabolic process // inferred from direct assay /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0009074 // aromatic amino acid family catabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // inferred from direct assay /// 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // non-traceable author statement /// 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0080130 // L-phenylalanine:2-oxoglutarate aminotransferase activity // inferred from electronic annotation 206917_at NM_006572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006572.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha 13 (GNA13), mRNA. /FEA=mRNA /GEN=GNA13 /PROD=guanine nucleotide binding protein (G protein),alpha 13 /DB_XREF=gi:5729847 /UG=Hs.1666 guanine nucleotide binding protein (G protein), alpha 13 /FL=gb:L22075.1 gb:NM_006572.1 NM_006572 guanine nucleotide binding protein (G protein), alpha 13 GNA13 10672 NM_001282425 /// NM_006572 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031526 // brush border membrane // not recorded /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031702 // type 1 angiotensin receptor binding // not recorded /// 0031752 // D5 dopamine receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 206918_s_at NM_003915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003915.1 /DEF=Homo sapiens copine I (CPNE1), mRNA. /FEA=mRNA /GEN=CPNE1 /PROD=copine I /DB_XREF=gi:4503012 /UG=Hs.166887 copine I /FL=gb:U83246.1 gb:NM_003915.1 NM_003915 copine I CPNE1 8904 NM_001198863 /// NM_003915 /// NM_152925 /// NM_152926 /// NM_152927 /// NM_152928 /// NM_152930 /// NM_152931 /// NR_037188 0006629 // lipid metabolic process // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // traceable author statement 206919_at NM_021795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021795.1 /DEF=Homo sapiens ELK4, ETS-domain protein (SRF accessory protein 1) (ELK4), transcript variant b, mRNA. /FEA=mRNA /GEN=ELK4 /PROD=ELK4 protein, isoform b /DB_XREF=gi:11496881 /UG=Hs.169241 ELK4, ETS-domain protein (SRF accessory protein 1) /FL=gb:NM_021795.1 gb:M85164.1 NM_021795 ELK4, ETS-domain protein (SRF accessory protein 1) ELK4 2005 NM_001973 /// NM_021795 /// XM_005244950 /// XM_005244951 /// XR_426764 /// XR_426765 /// XR_426766 /// XR_426767 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0070932 // histone H3 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001047 // core promoter binding // traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206920_s_at NM_001499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001499.1 /DEF=Homo sapiens GLE1 (yeast homolog)-like, RNA export mediator (GLE1L), mRNA. /FEA=mRNA /GEN=GLE1L /PROD=GLE1-like, RNA export mediator /DB_XREF=gi:4557626 /UG=Hs.169363 GLE1 (yeast homolog)-like, RNA export mediator /FL=gb:AF058922.1 gb:NM_001499.1 NM_001499 GLE1 RNA export mediator GLE1 2733 NM_001003722 /// NM_001499 /// XM_005251925 /// XM_006717058 /// XM_006717059 /// XM_006717060 /// XM_006717061 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 206921_at NM_001499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001499.1 /DEF=Homo sapiens GLE1 (yeast homolog)-like, RNA export mediator (GLE1L), mRNA. /FEA=mRNA /GEN=GLE1L /PROD=GLE1-like, RNA export mediator /DB_XREF=gi:4557626 /UG=Hs.169363 GLE1 (yeast homolog)-like, RNA export mediator /FL=gb:AF058922.1 gb:NM_001499.1 NM_001499 GLE1 RNA export mediator GLE1 2733 NM_001003722 /// NM_001499 /// XM_005251925 /// XM_006717058 /// XM_006717059 /// XM_006717060 /// XM_006717061 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 206922_at NM_004679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004679.1 /DEF=Homo sapiens variable charge, Y chromosome (VCY), mRNA. /FEA=mRNA /GEN=VCY /PROD=variable charge, Y chromosome /DB_XREF=gi:4759303 /UG=Hs.170076 variable charge, Y chromosome /FL=gb:AF000979.1 gb:NM_004679.1 NM_004679 variable charge, Y-linked /// variable charge, Y-linked 1B VCY /// VCY1B 9084 /// 353513 NM_004679 /// NM_181880 206923_at NM_002737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002737.1 /DEF=Homo sapiens protein kinase C, alpha (PRKCA), mRNA. /FEA=mRNA /GEN=PRKCA /PROD=protein kinase C, alpha /DB_XREF=gi:4506066 /UG=Hs.169449 protein kinase C, alpha /FL=gb:NM_002737.1 NM_002737 protein kinase C, alpha PRKCA 5578 NM_002737 /// XM_006721972 /// XR_243672 /// XR_243673 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0036289 // peptidyl-serine autophosphorylation // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation /// 0090330 // regulation of platelet aggregation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2000707 // positive regulation of dense core granule biogenesis // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004698 // calcium-dependent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206924_at NM_000641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000641.1 /DEF=Homo sapiens interleukin 11 (IL11), mRNA. /FEA=mRNA /GEN=IL11 /PROD=interleukin 11 /DB_XREF=gi:10834993 /UG=Hs.1721 interleukin 11 /FL=gb:NM_000641.1 gb:M57765.1 NM_000641 interleukin 11 IL11 3589 NM_000641 /// NM_001267718 0007267 // cell-cell signaling // inferred by curator /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030219 // megakaryocyte differentiation // non-traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046888 // negative regulation of hormone secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005576 // extracellular region // inferred by curator /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005142 // interleukin-11 receptor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay 206925_at NM_005668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005668.1 /DEF=Homo sapiens sialyltransferase 8 (alpha-2, 8-polysialytransferase) D (SIAT8D), mRNA. /FEA=mRNA /GEN=SIAT8D /PROD=sialyltransferase 8 (alpha-2,8-polysialytransferase) D /DB_XREF=gi:5031998 /UG=Hs.170180 sialyltransferase 8 (alpha-2, 8-polysialytransferase) D /FL=gb:NM_005668.1 gb:L41680.1 NM_005668 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 ST8SIA4 7903 NM_005668 /// NM_175052 /// XM_005272078 0001574 // ganglioside biosynthetic process // inferred from direct assay /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from direct assay /// 0006491 // N-glycan processing // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred by curator 206926_s_at M57765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57765.1 /DEF=Human interleukin 11 mRNA, complete cds. /FEA=mRNA /GEN=IL11 /PROD=interleukin 11 /DB_XREF=gi:186272 /UG=Hs.1721 interleukin 11 /FL=gb:NM_000641.1 gb:M57765.1 M57765 interleukin 11 IL11 3589 NM_000641 /// NM_001267718 0007267 // cell-cell signaling // inferred by curator /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030219 // megakaryocyte differentiation // non-traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046888 // negative regulation of hormone secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005576 // extracellular region // inferred by curator /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005142 // interleukin-11 receptor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay 206927_s_at NM_000855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000855.1 /DEF=Homo sapiens guanylate cyclase 1, soluble, alpha 2 (GUCY1A2), mRNA. /FEA=mRNA /GEN=GUCY1A2 /PROD=guanylate cyclase 1, soluble, alpha 2 /DB_XREF=gi:4504210 /UG=Hs.178295 guanylate cyclase 1, soluble, alpha 2 /FL=gb:NM_000855.1 NM_000855 guanylate cyclase 1, soluble, alpha 2 GUCY1A2 2977 NM_000855 /// NM_001256424 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 206928_at NM_003431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003431.1 /DEF=Homo sapiens zinc finger protein 124 (HZF-16) (ZNF124), mRNA. /FEA=mRNA /GEN=ZNF124 /PROD=zinc finger protein 124 (HZF-16) /DB_XREF=gi:4507976 /UG=Hs.180248 zinc finger protein 124 (HZF-16) /FL=gb:NM_003431.1 NM_003431 zinc finger protein 124 ZNF124 7678 NM_001243740 /// NM_003431 /// XM_005273256 /// XM_005273257 /// XM_006711813 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206929_s_at NM_005597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005597.1 /DEF=Homo sapiens nuclear factor IC (CCAAT-binding transcription factor) (NFIC), mRNA. /FEA=mRNA /GEN=NFIC /PROD=nuclear factor IC (CCAAT-binding transcriptionfactor) /DB_XREF=gi:10835080 /UG=Hs.184771 nuclear factor IC (CCAAT-binding transcription factor) /FL=gb:NM_005597.1 NM_005597 nuclear factor I/C (CCAAT-binding transcription factor) NFIC 4782 NM_001245002 /// NM_001245004 /// NM_001245005 /// NM_005597 /// NM_205843 /// XM_005259563 /// XM_005259564 /// XM_006722759 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 206930_at NM_005838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005838.1 /DEF=Homo sapiens putative glycine-N-acyltransferase (GAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=GAT /PROD=putative glycine-N-acyltransferase /DB_XREF=gi:5031708 /UG=Hs.18508 putative glycine-N-acyltransferase /FL=gb:AF023466.1 gb:NM_005838.1 NM_005838 glycine-N-acyltransferase GLYAT 10249 NM_005838 /// NM_201648 0006544 // glycine metabolic process // inferred from sequence or structural similarity /// 0006637 // acyl-CoA metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0032787 // monocarboxylic acid metabolic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0047961 // glycine N-acyltransferase activity // inferred from electronic annotation /// 0047962 // glycine N-benzoyltransferase activity // inferred from sequence or structural similarity 206931_at NM_003441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003441.1 /DEF=Homo sapiens zinc finger protein 141 (clone pHZ-44) (ZNF141), mRNA. /FEA=mRNA /GEN=ZNF141 /PROD=zinc finger protein 141 (clone pHZ-44) /DB_XREF=gi:4507992 /UG=Hs.193677 zinc finger protein 141 (clone pHZ-44) /FL=gb:L15309.1 gb:NM_003441.1 NM_003441 zinc finger protein 141 ZNF141 7700 NM_003441 /// XM_005278365 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0035108 // limb morphogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206932_at NM_003956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003956.1 /DEF=Homo sapiens cholesterol 25-hydroxylase (CH25H), mRNA. /FEA=mRNA /GEN=CH25H /PROD=cholesterol 25-hydroxylase /DB_XREF=gi:4502498 /UG=Hs.194687 cholesterol 25-hydroxylase /FL=gb:AF059214.1 gb:NM_003956.1 NM_003956 cholesterol 25-hydroxylase CH25H 9023 NM_003956 0006629 // lipid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001567 // cholesterol 25-hydroxylase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206933_s_at NM_004285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004285.1 /DEF=Homo sapiens hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (H6PD), mRNA. /FEA=mRNA /GEN=H6PD /PROD=hexose-6-phosphate dehydrogenase precursor /DB_XREF=gi:4758497 /UG=Hs.194728 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) /FL=gb:NM_004285.1 NM_004285 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) H6PD 9563 NM_001282587 /// NM_004285 /// XM_005263539 /// XM_005263540 /// XM_005263541 /// XM_006711052 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097305 // response to alcohol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017057 // 6-phosphogluconolactonase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0047936 // glucose 1-dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 206934_at NM_006065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006065.1 /DEF=Homo sapiens signal regulatory protein, beta, 1 (SIRP-BETA-1), mRNA. /FEA=mRNA /GEN=SIRP-BETA-1 /PROD=signal regulatory protein, beta, 1 /DB_XREF=gi:5174678 /UG=Hs.194784 signal regulatory protein, beta, 1 /FL=gb:NM_006065.1 NM_006065 signal-regulatory protein beta 1 SIRPB1 10326 NM_001083910 /// NM_001135844 /// NM_006065 /// XM_005260641 /// XM_005260643 /// XM_005260644 /// XM_006710250 /// XM_006723535 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 206935_at NM_002590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002590.2 /DEF=Homo sapiens protocadherin 8 (PCDH8), mRNA. /FEA=mRNA /GEN=PCDH8 /PROD=protocadherin 8 /DB_XREF=gi:6631101 /UG=Hs.19492 protocadherin 8 /FL=gb:AF061573.2 gb:NM_002590.2 NM_002590 protocadherin 8 PCDH8 5100 NM_002590 /// NM_032949 0001756 // somitogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 206936_x_at NM_022335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022335.1 /DEF=Homo sapiens hypothetical protein PRO2849 (PRO2849), mRNA. /FEA=mRNA /GEN=PRO2849 /PROD=hypothetical protein PRO2849 /DB_XREF=gi:11641234 /UG=Hs.19522 hypothetical protein PRO2849 /FL=gb:NM_022335.1 gb:AF119904.1 NM_022335 206937_at NM_003126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003126.1 /DEF=Homo sapiens spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (SPTA1), mRNA. /FEA=mRNA /GEN=SPTA1 /PROD=spectrin, alpha, erythrocytic 1 (elliptocytosis2) /DB_XREF=gi:4507188 /UG=Hs.1985 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) /FL=gb:M61877.1 gb:NM_003126.1 NM_003126 spectrin, alpha, erythrocytic 1 SPTA1 6708 NM_003126 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007015 // actin filament organization // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // traceable author statement /// 0032437 // cuticular plate // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 206938_at NM_000348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000348.1 /DEF=Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (SRD5A2), mRNA. /FEA=mRNA /GEN=SRD5A2 /PROD=3-oxo-5 alpha-steroid 4-dehydrogenase 2 /DB_XREF=gi:4557854 /UG=Hs.1989 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) /FL=gb:M74047.1 gb:NM_000348.1 NM_000348 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) SRD5A2 6716 NM_000348 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // inferred from direct assay /// 0008584 // male gonad development // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003865 // 3-oxo-5-alpha-steroid 4-dehydrogenase activity // inferred from electronic annotation /// 0009917 // sterol 5-alpha reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0047751 // cholestenone 5-alpha-reductase activity // inferred from electronic annotation 206939_at NM_005215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005215.1 /DEF=Homo sapiens deleted in colorectal carcinoma (DCC), mRNA. /FEA=mRNA /GEN=DCC /PROD=deleted in colorectal carcinoma /DB_XREF=gi:4885174 /UG=Hs.211567 deleted in colorectal carcinoma /FL=gb:NM_005215.1 NM_005215 DCC netrin 1 receptor DCC 1630 NM_005215 /// XM_005258204 0001764 // neuron migration // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // traceable author statement /// 0021965 // spinal cord ventral commissure morphogenesis // inferred from electronic annotation /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0033564 // anterior/posterior axon guidance // inferred from electronic annotation /// 0038007 // netrin-activated signaling pathway // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0048671 // negative regulation of collateral sprouting // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 2000171 // negative regulation of dendrite development // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005042 // netrin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 206940_s_at NM_006237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006237.1 /DEF=Homo sapiens POU domain, class 4, transcription factor 1 (POU4F1), mRNA. /FEA=mRNA /GEN=POU4F1 /PROD=POU domain, class 4, transcription factor 1 /DB_XREF=gi:5453937 /UG=Hs.211588 POU domain, class 4, transcription factor 1 /FL=gb:NM_006237.1 NM_006237 POU class 4 homeobox 1 POU4F1 5457 NM_006237 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0003223 // ventricular compact myocardium morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007498 // mesoderm development // inferred from electronic annotation /// 0021535 // cell migration in hindbrain // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0021986 // habenula development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048665 // neuron fate specification // inferred from sequence or structural similarity /// 0048880 // sensory system development // inferred from sequence or structural similarity /// 0048934 // peripheral nervous system neuron differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051355 // proprioception involved in equilibrioception // inferred from electronic annotation /// 0060384 // innervation // traceable author statement 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 206941_x_at NM_012431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012431.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (SEMA3E), mRNA. /FEA=mRNA /GEN=SEMA3E /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3E /DB_XREF=gi:6912649 /UG=Hs.212414 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E /FL=gb:AB002329.1 gb:NM_012431.1 NM_012431 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E SEMA3E 9723 NM_001178129 /// NM_012431 /// XM_006716187 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206942_s_at NM_002674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002674.1 /DEF=Homo sapiens pro-melanin-concentrating hormone (PMCH), mRNA. /FEA=mRNA /GEN=PMCH /PROD=pro-melanin-concentrating hormone /DB_XREF=gi:4505898 /UG=Hs.2182 pro-melanin-concentrating hormone /FL=gb:M57703.1 gb:NM_002674.1 NM_002674 pro-melanin-concentrating hormone PMCH 5367 NM_002674 0007165 // signal transduction // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007610 // behavior // non-traceable author statement /// 0007631 // feeding behavior // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0030354 // melanin-concentrating hormone activity // inferred from electronic annotation 206943_at NM_004612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004612.1 /DEF=Homo sapiens transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) (TGFBR1), mRNA. /FEA=mRNA /GEN=TGFBR1 /PROD=transforming growth factor, beta receptor I(activin A receptor type II-like kinase, 53kD) /DB_XREF=gi:4759225 /UG=Hs.220 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) /FL=gb:L11695.1 gb:NM_004612.1 NM_004612 transforming growth factor, beta receptor 1 TGFBR1 7046 NM_001130916 /// NM_004612 /// XM_005252150 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred by curator /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008354 // germ cell migration // inferred from sequence or structural similarity /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042060 // wound healing // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043062 // extracellular structure organization // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // traceable author statement /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from mutant phenotype /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060017 // parathyroid gland development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0070723 // response to cholesterol // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator 0000166 // nucleotide binding // inferred from electronic annotation /// 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred by curator /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from mutant phenotype /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from mutant phenotype /// 0050431 // transforming growth factor beta binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction 206944_at AF007141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007141.1 /DEF=Homo sapiens clone 23925 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852618 /UG=Hs.22180 5-hydroxytryptamine (serotonin) receptor 6 /FL=gb:L41147.1 gb:NM_000871.1 AF007141 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled HTR6 3362 NM_000871 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014053 // negative regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014058 // negative regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // traceable author statement /// 0004993 // serotonin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206945_at NM_002299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002299.1 /DEF=Homo sapiens lactase (LCT), mRNA. /FEA=mRNA /GEN=LCT /PROD=lactase /DB_XREF=gi:4504966 /UG=Hs.2251 lactase /FL=gb:NM_002299.1 NM_002299 lactase LCT 3938 NM_002299 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044245 // polysaccharide digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0000016 // lactase activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0017042 // glycosylceramidase activity // inferred from electronic annotation 206946_at NM_005477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005477.1 /DEF=Homo sapiens hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (HCN4), mRNA. /FEA=mRNA /GEN=HCN4 /PROD=hyperpolarization activated cyclicnucleotide-gated potassium channel 4 /DB_XREF=gi:4885406 /UG=Hs.225671 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 /FL=gb:NM_005477.1 NM_005477 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 HCN4 10021 NM_005477 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008015 // blood circulation // non-traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // not recorded /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from mutant phenotype /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // inferred from mutant phenotype /// 0005261 // cation channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 206947_at NM_006057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006057.1 /DEF=Homo sapiens UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (B3GALT5), mRNA. /FEA=mRNA /GEN=B3GALT5 /PROD=UDP-Gal:betaGlcNAc beta1,3-galactosyltransferase, polypeptide 5 /DB_XREF=gi:5174396 /UG=Hs.225943 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 /FL=gb:AB020337.1 gb:NM_006057.1 NM_006057 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 B3GALT5 10317 NM_001278650 /// NM_006057 /// NM_033170 /// NM_033171 /// NM_033172 /// NM_033173 /// XM_005260912 0006486 // protein glycosylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 206948_at NM_006656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006656.2 /DEF=Homo sapiens sialidase 3 (membrane sialidase) (NEU3), mRNA. /FEA=mRNA /GEN=NEU3 /PROD=sialidase 3 (membrane sialidase) /DB_XREF=gi:5803107 /UG=Hs.225947 sialidase 3 (membrane sialidase) /FL=gb:AB008185.2 gb:NM_006656.2 NM_006656 sialidase 3 (membrane sialidase) NEU3 10825 NM_006656 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004308 // exo-alpha-sialidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016997 // alpha-sialidase activity // inferred from direct assay /// 0052794 // exo-alpha-(2->3)-sialidase activity // inferred from sequence or structural similarity /// 0052795 // exo-alpha-(2->6)-sialidase activity // inferred from electronic annotation /// 0052796 // exo-alpha-(2->8)-sialidase activity // inferred from sequence or structural similarity 206949_s_at NM_014328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014328.1 /DEF=Homo sapiens nesca protein (NESCA), mRNA. /FEA=mRNA /GEN=NESCA /PROD=nesca protein /DB_XREF=gi:7657370 /UG=Hs.226499 nesca protein /FL=gb:AB026894.2 gb:NM_014328.1 NM_014328 RUN and SH3 domain containing 1 RUSC1 23623 NM_001105203 /// NM_001105204 /// NM_001105205 /// NM_001278227 /// NM_001278228 /// NM_001278229 /// NM_001278230 /// NM_014328 /// NR_103478 /// XM_006711254 /// XM_006711255 /// XM_006711256 /// XM_006711257 /// XM_006711258 0000209 // protein polyubiquitination // inferred from direct assay /// 0009967 // positive regulation of signal transduction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206950_at NM_002977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002977.1 /DEF=Homo sapiens sodium channel, voltage-gated, type IX, alpha polypeptide (SCN9A), mRNA. /FEA=mRNA /GEN=SCN9A /PROD=sodium channel, voltage-gated, type IX, alphapolypeptide /DB_XREF=gi:4506812 /UG=Hs.2319 sodium channel, voltage-gated, type IX, alpha polypeptide /FL=gb:NM_002977.1 NM_002977 sodium channel, voltage-gated, type IX, alpha subunit SCN9A 6335 NM_002977 /// XM_005246757 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation 206951_at NM_003545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003545.2 /DEF=Homo sapiens H4 histone family, member J (H4FJ), mRNA. /FEA=mRNA /GEN=H4FJ /PROD=H4 histone family, member J /DB_XREF=gi:5579467 /UG=Hs.240135 H4 histone family, member J /FL=gb:NM_003545.2 NM_003545 histone cluster 1, H4e HIST1H4E 8367 NM_003545 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 206952_at NM_000151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000151.1 /DEF=Homo sapiens glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) (G6PC), mRNA. /FEA=mRNA /GEN=G6PC /PROD=glucose-6-phosphatase, catalytic /DB_XREF=gi:4557598 /UG=Hs.242 glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) /FL=gb:U01120.1 gb:NM_000151.1 NM_000151 glucose-6-phosphatase, catalytic subunit G6PC 2538 NM_000151 /// NM_001270397 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from mutant phenotype /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046415 // urate metabolic process // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004346 // glucose-6-phosphatase activity // inferred from direct assay /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from mutant phenotype 206953_s_at NM_012302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012302.1 /DEF=Homo sapiens latrophilin (KIAA0786), mRNA. /FEA=mRNA /GEN=KIAA0786 /PROD=latrophilin /DB_XREF=gi:6912463 /UG=Hs.24212 latrophilin /FL=gb:AF104939.1 gb:NM_012302.1 NM_012302 uncharacterized LOC101927458 /// latrophilin 2 LOC101927458 /// LPHN2 23266 /// 101927458 NM_012302 /// XM_005270666 /// XM_005270667 /// XM_005270668 /// XM_005270670 /// XM_005270673 /// XM_005270674 /// XM_006710485 /// XM_006710486 /// XM_006710487 /// XM_006710488 /// XM_006710489 /// XM_006710490 /// XM_006710491 /// XM_006710492 /// XM_006710493 /// XM_006710494 /// XM_006710495 /// XM_006710496 /// XM_006710497 /// XR_246350 /// XR_246351 /// XR_248785 /// XR_248786 /// XR_250767 /// XR_250768 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016524 // latrotoxin receptor activity // non-traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 206954_at NM_015855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015855.1 /DEF=Homo sapiens Wilms tumor associated protein (WIT-1), mRNA. /FEA=mRNA /GEN=WIT-1 /PROD=Wilms tumor associated protein /DB_XREF=gi:7706770 /UG=Hs.251573 Wilms tumor associated protein /FL=gb:BC002734.1 gb:M60614.1 gb:NM_015855.1 NM_015855 WT1 antisense RNA WT1-AS 51352 NM_015855 /// NR_023920 /// NR_120546 /// NR_120547 /// NR_120548 /// NR_120549 206955_at NM_001170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001170.1 /DEF=Homo sapiens aquaporin 7 (AQP7), mRNA. /FEA=mRNA /GEN=AQP7 /PROD=aquaporin 7 /DB_XREF=gi:4502186 /UG=Hs.25475 aquaporin 7 /FL=gb:AB006190.1 gb:NM_001170.1 NM_001170 aquaporin 7 /// putative aquaporin-7-like protein 3-like /// putative aquaporin-7-like protein 3-like AQP7 /// LOC100509620 /// LOC101930168 364 /// 100509620 /// 101930168 NM_001170 /// XM_003403755 /// XM_005251453 /// XM_005251454 /// XM_005275922 /// XM_005276965 /// XM_006710129 /// XM_006710130 /// XM_006710131 /// XM_006710132 /// XM_006710133 /// XM_006712884 /// XM_006712885 /// XM_006712886 /// XM_006712887 /// XM_006716765 /// XM_006726489 /// XM_006726490 /// XR_254243 /// XR_425425 /// XR_425426 /// XR_425427 /// XR_425428 /// XR_425429 /// XR_425430 /// XR_425431 /// XR_425432 /// XR_425433 /// XR_425434 /// XR_427127 /// XR_427128 /// XR_427129 /// XR_427130 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0015793 // glycerol transport // traceable author statement /// 0015840 // urea transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071918 // urea transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015250 // water channel activity // traceable author statement /// 0015254 // glycerol channel activity // not recorded /// 0015265 // urea channel activity // inferred from electronic annotation 206956_at NM_000711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000711.1 /DEF=Homo sapiens bone gamma-carboxyglutamate (gla) protein (osteocalcin) (BGLAP), mRNA. /FEA=mRNA /GEN=BGLAP /PROD=bone gamma-carboxyglutamate (gla) protein(osteocalcin) /DB_XREF=gi:4502400 /UG=Hs.2558 bone gamma-carboxyglutamate (gla) protein (osteocalcin) /FL=gb:NM_000711.1 NM_000711 bone gamma-carboxyglutamate (gla) protein /// polyamine-modulated factor 1 /// PMF1-BGLAP readthrough BGLAP /// PMF1 /// PMF1-BGLAP 632 /// 11243 /// 100527963 NM_001199653 /// NM_001199654 /// NM_001199661 /// NM_001199662 /// NM_001199663 /// NM_001199664 /// NM_007221 /// NM_199173 0000278 // mitotic cell cycle // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0030282 // bone mineralization // non-traceable author statement /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032571 // response to vitamin K // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from expression pattern /// 0033574 // response to testosterone // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0042476 // odontogenesis // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045124 // regulation of bone resorption // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008147 // structural constituent of bone // non-traceable author statement /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0046848 // hydroxyapatite binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206957_at NM_016236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016236.1 /DEF=Homo sapiens alanine-glyoxylate aminotransferase homolog (TLH6), mRNA. /FEA=mRNA /GEN=TLH6 /PROD=alanine-glyoxylate aminotransferase homolog /DB_XREF=gi:7706736 /UG=Hs.271366 alanine-glyoxylate aminotransferase homolog /FL=gb:AF191687.1 gb:NM_016236.1 NM_016236 alanine-glyoxylate aminotransferase AGXT 189 NM_000030 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009436 // glyoxylate catabolic process // inferred from direct assay /// 0019265 // glycine biosynthetic process, by transamination of glyoxylate // inferred from direct assay /// 0019448 // L-cysteine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042853 // L-alanine catabolic process // inferred from direct assay /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // inferred from mutant phenotype /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0046724 // oxalic acid secretion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004760 // serine-pyruvate transaminase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008453 // alanine-glyoxylate transaminase activity // inferred from direct assay /// 0008453 // alanine-glyoxylate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay 206958_s_at AF318575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF318575.1 /DEF=Homo sapiens UPF3 (UPF3) mRNA, complete cds. /FEA=mRNA /GEN=UPF3 /PROD=UPF3 /DB_XREF=gi:12620405 /UG=Hs.274412 similar to yeast Upf3, variant A /FL=gb:AY013250.1 gb:AF318575.1 gb:NM_023011.1 AF318575 UPF3 regulator of nonsense transcripts homolog A (yeast) UPF3A 65110 NM_023011 /// NM_080687 /// XM_005266200 /// XM_005266201 /// XM_005266202 /// XM_006719991 /// XR_429283 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0035145 // exon-exon junction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206959_s_at NM_023011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023011.1 /DEF=Homo sapiens similar to yeast Upf3, variant A (UPF3A), mRNA. /FEA=mRNA /GEN=UPF3A /PROD=similar to yeast Upf3, variant A /DB_XREF=gi:12711675 /UG=Hs.274412 similar to yeast Upf3, variant A /FL=gb:AY013250.1 gb:AF318575.1 gb:NM_023011.1 NM_023011 UPF3 regulator of nonsense transcripts homolog A (yeast) UPF3A 65110 NM_023011 /// NM_080687 /// XM_005266200 /// XM_005266201 /// XM_005266202 /// XM_006719991 /// XR_429283 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0035145 // exon-exon junction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206960_at NM_005296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005296.1 /DEF=Homo sapiens G protein-coupled receptor 23 (GPR23), mRNA. /FEA=mRNA /GEN=GPR23 /PROD=G protein-coupled receptor 23 /DB_XREF=gi:4885310 /UG=Hs.27812 G protein-coupled receptor 23 /FL=gb:U90322.1 gb:NM_005296.1 NM_005296 lysophosphatidic acid receptor 4 LPAR4 2846 NM_001278000 /// NM_005296 /// XM_005262126 /// XM_006724639 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 206961_s_at NM_004275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004275.1 /DEF=Homo sapiens TRF-proximal protein (TRFP), mRNA. /FEA=mRNA /GEN=TRFP /PROD=TRF-proximal protein /DB_XREF=gi:4759261 /UG=Hs.278434 TRF-proximal protein /FL=gb:AF097725.1 gb:NM_004275.1 NM_004275 mediator complex subunit 20 MED20 9477 NM_004275 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // non-traceable author statement 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 206962_x_at NM_014120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014120.1 /DEF=Homo sapiens PRO0214 protein (PRO0214), mRNA. /FEA=mRNA /GEN=PRO0214 /PROD=PRO0214 protein /DB_XREF=gi:7662533 /UG=Hs.278932 PRO0214 protein /FL=gb:AF090903.1 gb:NM_014120.1 NM_014120 206963_s_at NM_016347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016347.1 /DEF=Homo sapiens putative N-acetyltransferase Camello 2 (CML2), mRNA. /FEA=mRNA /GEN=CML2 /PROD=putative N-acetyltransferase Camello 2 /DB_XREF=gi:7705327 /UG=Hs.278983 putative N-acetyltransferase Camello 2 /FL=gb:AF185571.1 gb:NM_016347.1 NM_016347 N-acetyltransferase 8 (GCN5-related, putative) /// N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) NAT8 /// NAT8B 9027 /// 51471 NM_003960 /// NM_016347 0001702 // gastrulation with mouth forming second // inferred from mutant phenotype /// 0001702 // gastrulation with mouth forming second // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008080 // N-acetyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 206964_at NM_016347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016347.1 /DEF=Homo sapiens putative N-acetyltransferase Camello 2 (CML2), mRNA. /FEA=mRNA /GEN=CML2 /PROD=putative N-acetyltransferase Camello 2 /DB_XREF=gi:7705327 /UG=Hs.278983 putative N-acetyltransferase Camello 2 /FL=gb:AF185571.1 gb:NM_016347.1 NM_016347 N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) NAT8B 51471 NM_016347 0001702 // gastrulation with mouth forming second // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0042493 // response to drug // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008080 // N-acetyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 206965_at NM_016285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016285.1 /DEF=Homo sapiens AP-2rep transcription factor (LOC51717), mRNA. /FEA=mRNA /GEN=LOC51717 /PROD=AP-2rep transcription factor /DB_XREF=gi:7706476 /UG=Hs.278998 AP-2rep transcription factor /FL=gb:AF113122.1 gb:AF161471.1 gb:NM_016285.1 NM_016285 Kruppel-like factor 12 KLF12 11278 NM_007249 /// NM_016285 /// XM_005266251 /// XM_005266252 /// XM_006719762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206966_s_at NM_016285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016285.1 /DEF=Homo sapiens AP-2rep transcription factor (LOC51717), mRNA. /FEA=mRNA /GEN=LOC51717 /PROD=AP-2rep transcription factor /DB_XREF=gi:7706476 /UG=Hs.278998 AP-2rep transcription factor /FL=gb:AF113122.1 gb:AF161471.1 gb:NM_016285.1 NM_016285 Kruppel-like factor 12 KLF12 11278 NM_007249 /// NM_016285 /// XM_005266251 /// XM_005266252 /// XM_006719762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 206967_at NM_001240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001240.1 /DEF=Homo sapiens cyclin T1 (CCNT1), mRNA. /FEA=mRNA /GEN=CCNT1 /PROD=cyclin T1 /DB_XREF=gi:4502626 /UG=Hs.279906 cyclin T1 /FL=gb:AF045161.1 gb:AF048730.1 gb:NM_001240.1 NM_001240 cyclin T1 CCNT1 904 NM_001240 /// NM_001277842 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from physical interaction /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 206968_s_at NM_006165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006165.1 /DEF=Homo sapiens nuclear factor related to kappa B binding protein (NFRKB), mRNA. /FEA=mRNA /GEN=NFRKB /PROD=nuclear factor related to kappa B bindingprotein /DB_XREF=gi:5453777 /UG=Hs.282441 nuclear factor related to kappa B binding protein /FL=gb:U08191.1 gb:NM_006165.1 NM_006165 nuclear factor related to kappaB binding protein NFRKB 4798 NM_001143835 /// NM_006165 /// XM_005271565 /// XM_005271566 /// XM_005271567 /// XM_005271568 /// XM_005271569 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206969_at NM_021013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021013.2 /DEF=Homo sapiens keratin, hair, acidic, 4 (KRTHA4), mRNA. /FEA=mRNA /GEN=KRTHA4 /PROD=type I hair keratin 4 /DB_XREF=gi:11641406 /UG=Hs.296942 keratin, hair, acidic, 4 /FL=gb:NM_021013.2 NM_021013 keratin 34 /// keratin, type I cuticular Ha4-like KRT34 /// LOC100653049 3885 /// 100653049 NM_021013 /// XM_003403882 0008544 // epidermis development // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 206970_at NM_005076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005076.1 /DEF=Homo sapiens contactin 2 (axonal) (CNTN2), mRNA. /FEA=mRNA /GEN=CNTN2 /PROD=contactin 2 (axonal) /DB_XREF=gi:4827021 /UG=Hs.2998 contactin 2 (axonal) /FL=gb:NM_005076.1 NM_005076 contactin 2 (axonal) CNTN2 6900 NM_005076 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0010769 // regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0010954 // positive regulation of protein processing // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0031133 // regulation of axon diameter // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0045163 // clustering of voltage-gated potassium channels // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048710 // regulation of astrocyte differentiation // inferred from electronic annotation /// 0060168 // positive regulation of adenosine receptor signaling pathway // inferred from electronic annotation /// 0071205 // protein localization to juxtaparanode region of axon // inferred from electronic annotation /// 0071206 // establishment of protein localization to juxtaparanode region of axon // inferred from electronic annotation /// 0097090 // presynaptic membrane organization // inferred from mutant phenotype 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0043621 // protein self-association // inferred from electronic annotation 206971_at NM_007369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007369.1 /DEF=Homo sapiens G-protein coupled receptor (RE2), mRNA. /FEA=mRNA /GEN=RE2 /PROD=G-protein coupled receptor /DB_XREF=gi:6677700 /UG=Hs.301642 G-protein coupled receptor /FL=gb:AF091890.1 gb:NM_007369.1 NM_007369 G protein-coupled receptor 161 GPR161 23432 NM_001267609 /// NM_001267610 /// NM_001267611 /// NM_001267612 /// NM_001267613 /// NM_001267614 /// NM_007369 /// NM_153832 /// XM_005245055 /// XM_005245056 /// XM_005245057 /// XM_006711251 /// XM_006711252 /// XM_006711253 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 1901621 // negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity 206972_s_at NM_007369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007369.1 /DEF=Homo sapiens G-protein coupled receptor (RE2), mRNA. /FEA=mRNA /GEN=RE2 /PROD=G-protein coupled receptor /DB_XREF=gi:6677700 /UG=Hs.301642 G-protein coupled receptor /FL=gb:AF091890.1 gb:NM_007369.1 NM_007369 G protein-coupled receptor 161 GPR161 23432 NM_001267609 /// NM_001267610 /// NM_001267611 /// NM_001267612 /// NM_001267613 /// NM_001267614 /// NM_007369 /// NM_153832 /// XM_005245055 /// XM_005245056 /// XM_005245057 /// XM_006711251 /// XM_006711252 /// XM_006711253 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 1901621 // negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity 206973_at NM_003625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003625.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (PPFIA2), mRNA. /FEA=mRNA /GEN=PPFIA2 /PROD=protein tyrosine phosphatase, receptor type, fpolypeptide (PTPRF), interacting protein (liprin), alpha2 /DB_XREF=gi:4505984 /UG=Hs.30881 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 /FL=gb:AF034799.1 gb:NM_003625.1 NM_003625 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 PPFIA2 8499 NM_001220473 /// NM_001220474 /// NM_001220475 /// NM_001220476 /// NM_001220477 /// NM_001220478 /// NM_001220479 /// NM_001220480 /// NM_001282536 /// NM_003625 /// XM_006719655 /// XM_006719656 /// XM_006719657 /// XM_006719658 /// XM_006719659 /// XM_006719660 /// XM_006719661 /// XM_006719662 /// XM_006719663 /// XM_006719664 /// XM_006719665 /// XM_006719666 /// XM_006719667 /// XM_006719668 /// XM_006719669 /// XM_006719670 0007160 // cell-matrix adhesion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 206974_at NM_006564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006564.1 /DEF=Homo sapiens G protein-coupled receptor (TYMSTR), mRNA. /FEA=mRNA /GEN=TYMSTR /PROD=G protein-coupled receptor /DB_XREF=gi:5730105 /UG=Hs.34526 G protein-coupled receptor /FL=gb:U73529.1 gb:AF007545.1 gb:NM_006564.1 NM_006564 chemokine (C-X-C motif) receptor 6 CXCR6 10663 NM_006564 /// XM_005264809 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation 206975_at NM_000595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000595.2 /DEF=Homo sapiens lymphotoxin alpha (TNF superfamily, member 1) (LTA), mRNA. /FEA=mRNA /GEN=LTA /PROD=lymphotoxin alpha precursor /DB_XREF=gi:6806892 /UG=Hs.36 lymphotoxin alpha (TNF superfamily, member 1) /FL=gb:D12614.1 gb:D00102.1 gb:NM_000595.2 NM_000595 lymphotoxin alpha LTA 4049 NM_000595 /// NM_001159740 0001666 // response to hypoxia // inferred from electronic annotation /// 0002876 // positive regulation of chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206976_s_at NM_006644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006644.1 /DEF=Homo sapiens heat shock 105kD (HSP105B), mRNA. /FEA=mRNA /GEN=HSP105B /PROD=heat shock 105kD /DB_XREF=gi:5729878 /UG=Hs.36927 heat shock 105kD /FL=gb:AB003333.1 gb:NM_006644.1 NM_006644 heat shock 105kDa/110kDa protein 1 HSPH1 10808 NM_001286503 /// NM_001286504 /// NM_001286505 /// NM_006644 /// XM_005266236 /// XM_006719757 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0045345 // positive regulation of MHC class I biosynthetic process // traceable author statement /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051135 // positive regulation of NK T cell activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation 206977_at NM_000315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000315.1 /DEF=Homo sapiens parathyroid hormone (PTH), mRNA. /FEA=mRNA /GEN=PTH /PROD=parathyroid hormone /DB_XREF=gi:4506266 /UG=Hs.37045 parathyroid hormone /FL=gb:NM_000315.1 NM_000315 parathyroid hormone PTH 5741 NM_000315 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034645 // cellular macromolecule biosynthetic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0045453 // bone resorption // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046058 // cAMP metabolic process // traceable author statement /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0071107 // response to parathyroid hormone // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005179 // hormone activity // inferred from electronic annotation /// 0031856 // parathyroid hormone receptor binding // inferred from electronic annotation /// 0031857 // type 1 parathyroid hormone receptor binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from direct assay 206978_at NM_000647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000647.2 /DEF=Homo sapiens chemokine (C-C motif) receptor 2 (CCR2), mRNA. /FEA=mRNA /GEN=CCR2 /PROD=chemokine (C-C motif) receptor 2 /DB_XREF=gi:4827072 /UG=Hs.395 chemokine (C-C motif) receptor 2 /FL=gb:U03882.1 gb:NM_000647.2 NM_000647 chemokine (C-C motif) receptor 2 CCR2 729230 NM_001123041 /// NM_001123396 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002829 // negative regulation of type 2 immune response // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0010574 // regulation of vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0010820 // positive regulation of T cell chemotaxis // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019725 // cellular homeostasis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032743 // positive regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0035705 // T-helper 17 cell chemotaxis // inferred from sequence or structural similarity /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from sequence or structural similarity /// 0043310 // negative regulation of eosinophil degranulation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from sequence or structural similarity /// 0090265 // positive regulation of immune complex clearance by monocytes and macrophages // inferred from sequence or structural similarity /// 2000439 // positive regulation of monocyte extravasation // inferred from sequence or structural similarity /// 2000451 // positive regulation of CD8-positive, alpha-beta T cell extravasation // inferred from sequence or structural similarity /// 2000464 // positive regulation of astrocyte chemotaxis // inferred from direct assay /// 2000473 // positive regulation of hematopoietic stem cell migration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation /// 0031727 // CCR2 chemokine receptor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 206979_at NM_000066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000066.1 /DEF=Homo sapiens complement component 8, beta polypeptide (C8B), mRNA. /FEA=mRNA /GEN=C8B /PROD=complement component 8, beta polypeptide /DB_XREF=gi:4557390 /UG=Hs.38069 complement component 8, beta polypeptide /FL=gb:M16973.1 gb:NM_000066.1 NM_000066 complement component 8, beta polypeptide C8B 732 NM_000066 /// NM_001278543 /// NM_001278544 /// XM_005271166 /// XM_006710873 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 206980_s_at NM_001459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001459.1 /DEF=Homo sapiens fms-related tyrosine kinase 3 ligand (FLT3LG), mRNA. /FEA=mRNA /GEN=FLT3LG /PROD=fms-related tyrosine kinase 3 ligand /DB_XREF=gi:4503750 /UG=Hs.428 fms-related tyrosine kinase 3 ligand /FL=gb:NM_001459.1 gb:U04806.1 NM_001459 fms-related tyrosine kinase 3 ligand FLT3LG 2323 NM_001204502 /// NM_001204503 /// NM_001278637 /// NM_001278638 /// NM_001459 /// XM_005258680 /// XM_005258681 /// XM_005258682 /// XM_005258683 /// XM_005258684 /// XM_005258685 /// XM_006723114 /// XM_006723115 /// XM_006723116 /// XM_006723117 /// XM_006723118 0007165 // signal transduction // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0031233 // intrinsic component of external side of plasma membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 206981_at NM_000334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000334.1 /DEF=Homo sapiens sodium channel, voltage-gated, type IV, alpha polypeptide (SCN4A), mRNA. /FEA=mRNA /GEN=SCN4A /PROD=sodium channel, voltage-gated, type IV, alphapolypeptide /DB_XREF=gi:4506806 /UG=Hs.46038 sodium channel, voltage-gated, type IV, alpha polypeptide /FL=gb:M81758.1 gb:NM_000334.1 NM_000334 sodium channel, voltage-gated, type IV, alpha subunit SCN4A 6329 NM_000334 /// XM_005257566 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 206982_at NM_005208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005208.2 /DEF=Homo sapiens crystallin, beta A1 (CRYBA1), mRNA. /FEA=mRNA /GEN=CRYBA1 /PROD=crystallin, beta A3 /DB_XREF=gi:12056460 /UG=Hs.46275 crystallin, beta A1 /FL=gb:NM_005208.2 NM_005208 crystallin, beta A1 CRYBA1 1411 NM_005208 /// XM_006721706 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007601 // visual perception // non-traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 206983_at NM_004367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004367.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 6 (CCR6), mRNA. /FEA=mRNA /GEN=CCR6 /PROD=chemokine (C-C motif) receptor 6 /DB_XREF=gi:4757939 /UG=Hs.46468 chemokine (C-C motif) receptor 6 /FL=gb:U60000.1 gb:U68030.1 gb:NM_004367.1 NM_004367 chemokine (C-C motif) receptor 6 CCR6 1235 NM_004367 /// NM_031409 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 206984_s_at NM_002930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002930.1 /DEF=Homo sapiens Ric (Drosophila)-like, expressed in neurons (RIN), mRNA. /FEA=mRNA /GEN=RIN /PROD=Ric (Drosophila)-like, expressed in neurons /DB_XREF=gi:4506532 /UG=Hs.47626 Ric (Drosophila)-like, expressed in neurons /FL=gb:U71204.1 gb:U78164.1 gb:NM_002930.1 NM_002930 Ras-like without CAAX 2 RIT2 6014 NM_001272077 /// NM_002930 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 206985_at NM_000197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000197.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 3 (HSD17B3), mRNA. /FEA=mRNA /GEN=HSD17B3 /PROD=estradiol 17 beta-dehydrogenase 3 /DB_XREF=gi:4557648 /UG=Hs.477 hydroxysteroid (17-beta) dehydrogenase 3 /FL=gb:NM_000197.1 gb:U05659.1 NM_000197 hydroxysteroid (17-beta) dehydrogenase 3 HSD17B3 3293 NM_000197 /// XM_005251970 /// XM_006717094 /// XM_006717095 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030539 // male genitalia development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061370 // testosterone biosynthetic process // inferred from electronic annotation 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047045 // testosterone 17-beta-dehydrogenase (NADP+) activity // inferred from electronic annotation 206986_at AB007422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007422.1 /DEF=Homo sapiens mRNA for fibroblast growth factor (FGF-18), complete cds. /FEA=CDS /PROD=fibroblast growth factor (FGF-18) /DB_XREF=gi:3355903 /UG=Hs.49585 fibroblast growth factor 18 /FL=gb:AB007422.1 gb:AF075292.1 gb:NM_003862.1 AB007422 fibroblast growth factor 18 FGF18 8817 NM_003862 /// NM_033649 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 206987_x_at NM_003862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003862.1 /DEF=Homo sapiens fibroblast growth factor 18 (FGF18), mRNA. /FEA=mRNA /GEN=FGF18 /PROD=fibroblast growth factor 18 /DB_XREF=gi:4503694 /UG=Hs.49585 fibroblast growth factor 18 /FL=gb:AB007422.1 gb:AF075292.1 gb:NM_003862.1 NM_003862 fibroblast growth factor 18 FGF18 8817 NM_003862 /// NM_033649 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 206988_at NM_005624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005624.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 25 (SCYA25), mRNA. /FEA=mRNA /GEN=SCYA25 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 25 /DB_XREF=gi:5032078 /UG=Hs.50404 small inducible cytokine subfamily A (Cys-Cys), member 25 /FL=gb:U86358.1 gb:NM_005624.1 NM_005624 chemokine (C-C motif) ligand 25 CCL25 6370 NM_001201359 /// NM_005624 /// NM_148888 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005179 // hormone activity // traceable author statement /// 0008009 // chemokine activity // inferred from electronic annotation /// 0031735 // CCR10 chemokine receptor binding // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from direct assay 206989_s_at NM_004719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004719.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 2, interacting protein (SFRS2IP), mRNA. /FEA=mRNA /GEN=SFRS2IP /PROD=splicing factor, arginineserine-rich 2,interacting protein /DB_XREF=gi:4759171 /UG=Hs.51957 splicing factor, arginineserine-rich 2, interacting protein /FL=gb:NM_004719.1 NM_004719 SR-related CTD-associated factor 11 SCAF11 9169 NM_004719 /// XM_005269230 /// XM_006719692 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 206990_at NM_003285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003285.1 /DEF=Homo sapiens tenascin R (restrictin, janusin) (TNR), mRNA. /FEA=mRNA /GEN=TNR /PROD=tenascin R (restrictin, janusin) /DB_XREF=gi:4507630 /UG=Hs.54433 tenascin R (restrictin, janusin) /FL=gb:NM_003285.1 NM_003285 tenascin R TNR 7143 NM_003285 0007155 // cell adhesion // non-traceable author statement /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0008306 // associative learning // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0048692 // negative regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0072534 // perineuronal net // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 206991_s_at NM_000579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000579.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 5 (CCR5), mRNA. /FEA=mRNA /GEN=CCR5 /PROD=chemokine (C-C motif) receptor 5 /DB_XREF=gi:4502638 /UG=Hs.54443 chemokine (C-C motif) receptor 5 /FL=gb:U54994.1 gb:U57840.1 gb:NM_000579.1 NM_000579 chemokine (C-C motif) receptor 5 (gene/pseudogene) CCR5 1234 NM_000579 /// NM_001100168 0000165 // MAPK cascade // inferred from expression pattern /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006816 // calcium ion transport // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0023052 // signaling // inferred from expression pattern /// 0030260 // entry into host cell // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // non-traceable author statement /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0070723 // response to cholesterol // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0016493 // C-C chemokine receptor activity // inferred from direct assay /// 0016493 // C-C chemokine receptor activity // non-traceable author statement /// 0019957 // C-C chemokine binding // inferred from physical interaction /// 0071791 // chemokine (C-C motif) ligand 5 binding // inferred from physical interaction 206992_s_at NM_015684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015684.1 /DEF=Homo sapiens hypothetical protein (HSU79253), mRNA. /FEA=mRNA /GEN=HSU79253 /PROD=hypothetical protein /DB_XREF=gi:7661835 /UG=Hs.56155 hypothetical protein /FL=gb:U79253.1 gb:NM_015684.1 NM_015684 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) ATP5S 27109 NM_001003803 /// NM_001003805 /// NM_015684 /// NR_033761 /// XM_005267537 /// XM_005267538 /// XM_005267539 /// XR_245682 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206993_at NM_015684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015684.1 /DEF=Homo sapiens hypothetical protein (HSU79253), mRNA. /FEA=mRNA /GEN=HSU79253 /PROD=hypothetical protein /DB_XREF=gi:7661835 /UG=Hs.56155 hypothetical protein /FL=gb:U79253.1 gb:NM_015684.1 NM_015684 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) ATP5S 27109 NM_001003803 /// NM_001003805 /// NM_015684 /// NR_033761 /// XM_005267537 /// XM_005267538 /// XM_005267539 /// XR_245682 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 206994_at NM_001899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001899.1 /DEF=Homo sapiens cystatin S (CST4), mRNA. /FEA=mRNA /GEN=CST4 /PROD=cystatin S /DB_XREF=gi:4503108 /UG=Hs.56319 cystatin S /FL=gb:NM_001899.1 NM_001899 cystatin S CST4 1472 NM_001899 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 206995_x_at NM_003693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003693.1 /DEF=Homo sapiens acetyl LDL receptor; SREC=scavenger receptor expressed by endothelial cells (SREC), mRNA. /FEA=mRNA /GEN=SREC /PROD=acetyl LDL receptor; SREC=scavenger receptorexpressed by endothelial cells /DB_XREF=gi:4507202 /UG=Hs.57735 acetyl LDL receptor; SREC /FL=gb:D63483.1 gb:D86864.1 gb:NM_003693.1 NM_003693 scavenger receptor class F, member 1 SCARF1 8578 NM_003693 /// NM_145350 /// NM_145352 /// NR_028075 /// NR_028076 /// NR_102409 0006707 // cholesterol catabolic process // inferred by curator /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from electronic annotation /// 0048680 // positive regulation of axon regeneration // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay 206996_x_at NM_000723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000723.1 /DEF=Homo sapiens calcium channel, voltage-dependent, beta 1 subunit (CACNB1), mRNA. /FEA=mRNA /GEN=CACNB1 /PROD=calcium channel, voltage-dependent, beta 1subunit /DB_XREF=gi:4502530 /UG=Hs.635 calcium channel, voltage-dependent, beta 1 subunit /FL=gb:M76560.1 gb:M92302.1 gb:L06111.1 gb:NM_000723.1 NM_000723 calcium channel, voltage-dependent, beta 1 subunit CACNB1 782 NM_000723 /// NM_199247 /// NM_199248 /// XM_005257645 /// XM_005257646 /// XM_005257647 /// XM_006722072 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from electronic annotation 206997_s_at NM_004807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004807.1 /DEF=Homo sapiens heparan sulfate 6-O-sulfotransferase (HS6ST), mRNA. /FEA=mRNA /GEN=HS6ST /PROD=heparan sulfate 6-O-sulfotransferase /DB_XREF=gi:4758565 /UG=Hs.6363 heparan sulfate 6-O-sulfotransferase /FL=gb:AB006179.1 gb:NM_004807.1 NM_004807 heparan sulfate 6-O-sulfotransferase 1 HS6ST1 9394 NM_004807 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0015015 // heparan sulfate proteoglycan biosynthetic process, enzymatic modification // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048666 // neuron development // inferred from mutant phenotype /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 206998_x_at NM_006249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006249.2 /DEF=Homo sapiens proline-rich protein BstNI subfamily 3 (PRB3), mRNA. /FEA=mRNA /GEN=PRB3 /PROD=proline-rich protein BstNI subfamily 3 /DB_XREF=gi:7427520 /UG=Hs.73031 proline-rich protein BstNI subfamily 3 /FL=gb:NM_006249.2 NM_006249 proline-rich protein BstNI subfamily 3 PRB3 5544 NM_006249 0050829 // defense response to Gram-negative bacterium // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 206999_at NM_001559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001559.1 /DEF=Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2), mRNA. /FEA=mRNA /GEN=IL12RB2 /PROD=interleukin 12 receptor, beta 2 /DB_XREF=gi:4504642 /UG=Hs.73165 interleukin 12 receptor, beta 2 /FL=gb:U64198.1 gb:NM_001559.1 NM_001559 interleukin 12 receptor, beta 2 IL12RB2 3595 NM_001258214 /// NM_001258215 /// NM_001258216 /// NM_001559 /// NR_047583 /// NR_047584 /// XM_005270825 /// XM_005270827 /// XM_005270828 /// XM_006710617 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 207000_s_at NM_005605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005605.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) (PPP3CC), mRNA. /FEA=mRNA /GEN=PPP3CC /PROD=protein phosphatase 3 (formerly 2B), catalyticsubunit, gamma isoform (calcineurin A gamma) /DB_XREF=gi:5031988 /UG=Hs.75206 protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) /FL=gb:NM_005605.1 gb:AY007249.1 NM_005605 protein phosphatase 3, catalytic subunit, gamma isozyme PPP3CC 5533 NM_001243974 /// NM_001243975 /// NM_005605 /// XM_005273564 /// XR_428312 0006915 // apoptotic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207001_x_at NM_004089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004089.1 /DEF=Homo sapiens delta sleep inducing peptide, immunoreactor (DSIPI), mRNA. /FEA=mRNA /GEN=DSIPI /PROD=delta sleep inducing peptide, immunoreactor /DB_XREF=gi:4758197 /UG=Hs.75450 delta sleep inducing peptide, immunoreactor /FL=gb:NM_004089.1 NM_004089 TSC22 domain family, member 3 TSC22D3 1831 NM_001015881 /// NM_004089 /// NM_198057 /// XM_005262098 /// XM_005262099 /// XM_005262100 /// XM_005262101 /// XM_005262102 /// XM_005262103 /// XM_006724629 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070236 // negative regulation of activation-induced cell death of T cells // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043426 // MRF binding // inferred from electronic annotation 207002_s_at NM_002656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002656.1 /DEF=Homo sapiens pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=PLAGL1 /PROD=pleiomorphic adenoma gene-like 1 isoform 1 /DB_XREF=gi:4505856 /UG=Hs.75825 pleiomorphic adenoma gene-like 1 /FL=gb:U81992.1 gb:NM_002656.1 NM_002656 pleiomorphic adenoma gene-like 1 PLAGL1 5325 NM_001080951 /// NM_001080952 /// NM_001080953 /// NM_001080954 /// NM_001080955 /// NM_001080956 /// NM_001289037 /// NM_001289038 /// NM_001289039 /// NM_001289040 /// NM_001289041 /// NM_001289042 /// NM_001289043 /// NM_001289044 /// NM_001289045 /// NM_001289046 /// NM_001289047 /// NM_001289048 /// NM_001289049 /// NM_002656 /// NM_006718 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207003_at NM_002098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002098.1 /DEF=Homo sapiens guanylate cyclase activator 1B (retina) (GUCA1B), mRNA. /FEA=mRNA /GEN=GUCA1B /PROD=guanylate cyclase activator 1B (retina) /DB_XREF=gi:4504208 /UG=Hs.778 guanylate cyclase activator 1B (retina) /FL=gb:M97496.1 gb:M95174.1 gb:NM_002098.1 NM_002098 guanylate cyclase activator 2A (guanylin) GUCA2A 2980 NM_033553 0007165 // signal transduction // non-traceable author statement /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // non-traceable author statement /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0030250 // guanylate cyclase activator activity // non-traceable author statement 207004_at NM_000657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000657.1 /DEF=Homo sapiens B-cell CLLlymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant beta, mRNA. /FEA=mRNA /GEN=BCL2 /PROD=B-cell lymphoma protein 2 beta /DB_XREF=gi:4557356 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13995.1 gb:NM_000657.1 NM_000657 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 207005_s_at NM_000657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000657.1 /DEF=Homo sapiens B-cell CLLlymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant beta, mRNA. /FEA=mRNA /GEN=BCL2 /PROD=B-cell lymphoma protein 2 beta /DB_XREF=gi:4557356 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13995.1 gb:NM_000657.1 NM_000657 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 207006_s_at NM_013301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013301.1 /DEF=Homo sapiens protein predicted by clone 23882 (HSU79303), mRNA. /FEA=mRNA /GEN=HSU79303 /PROD=protein predicted by clone 23882 /DB_XREF=gi:9558742 /UG=Hs.82482 protein predicted by clone 23882 /FL=gb:U79303.1 gb:NM_013301.1 NM_013301 coiled-coil domain containing 106 CCDC106 29903 NM_013301 /// XM_005258827 /// XM_005258828 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 207007_at NM_005122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005122.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), mRNA. /FEA=mRNA /GEN=NR1I3 /PROD=nuclear receptor subfamily 1, group I, member 3 /DB_XREF=gi:4826660 /UG=Hs.83623 nuclear receptor subfamily 1, group I, member 3 /FL=gb:NM_005122.1 NM_005122 nuclear receptor subfamily 1, group I, member 3 NR1I3 9970 NM_001077469 /// NM_001077470 /// NM_001077471 /// NM_001077472 /// NM_001077473 /// NM_001077474 /// NM_001077475 /// NM_001077476 /// NM_001077477 /// NM_001077478 /// NM_001077479 /// NM_001077480 /// NM_001077481 /// NM_001077482 /// NM_005122 /// XM_005245693 /// XM_005245694 /// XM_005245697 /// XM_006711696 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030521 // androgen receptor signaling pathway // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004882 // androgen receptor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207008_at NM_001557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001557.1 /DEF=Homo sapiens interleukin 8 receptor, beta (IL8RB), mRNA. /FEA=mRNA /GEN=IL8RB /PROD=interleukin 8 receptor, beta /DB_XREF=gi:4504682 /UG=Hs.846 interleukin 8 receptor, beta /FL=gb:M94582.1 gb:M73969.1 gb:NM_001557.1 gb:L19593.1 NM_001557 chemokine (C-X-C motif) receptor 2 CXCR2 3579 NM_001168298 /// NM_001557 /// XM_005246530 /// XM_005246531 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002438 // acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0006968 // cellular defense response // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030901 // midbrain development // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033030 // negative regulation of neutrophil apoptotic process // inferred from electronic annotation /// 0038112 // interleukin-8-mediated signaling pathway // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0072173 // metanephric tubule morphogenesis // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from direct assay 0004871 // signal transducer activity // inferred from direct assay /// 0004918 // interleukin-8 receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016494 // C-X-C chemokine receptor activity // inferred from direct assay /// 0019959 // interleukin-8 binding // inferred from physical interaction 207009_at NM_003924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003924.2 /DEF=Homo sapiens paired mesoderm homeobox 2b (PMX2B), mRNA. /FEA=mRNA /GEN=PMX2B /PROD=paired mesoderm homeobox 2b /DB_XREF=gi:12707579 /UG=Hs.87202 paired mesoderm homeobox 2b /FL=gb:NM_003924.2 gb:D82344.1 NM_003924 paired-like homeobox 2b PHOX2B 8929 NM_003924 0001764 // neuron migration // inferred from sequence or structural similarity /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred by curator /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0003360 // brainstem development // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0021533 // cell differentiation in hindbrain // inferred from sequence or structural similarity /// 0021723 // medullary reticular formation development // inferred from sequence or structural similarity /// 0021934 // hindbrain tangential cell migration // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048468 // cell development // inferred from electronic annotation /// 0048483 // autonomic nervous system development // inferred from mutant phenotype /// 0048484 // enteric nervous system development // inferred from expression pattern /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048486 // parasympathetic nervous system development // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0048894 // efferent axon development in a lateral line nerve // inferred from sequence or structural similarity /// 0060541 // respiratory system development // inferred from sequence or structural similarity /// 0061452 // retrotrapezoid nucleus neuron differentiation // inferred from sequence or structural similarity /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071157 // negative regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071542 // dopaminergic neuron differentiation // inferred by curator /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901166 // neural crest cell migration involved in autonomic nervous system development // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207010_at NM_000812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000812.2 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1), mRNA. /FEA=mRNA /GEN=GABRB1 /PROD=gamma-aminobutyric acid (GABA) A receptor, beta1 precursor /DB_XREF=gi:12548775 /UG=Hs.89768 gamma-aminobutyric acid (GABA) A receptor, beta 1 /FL=gb:NM_000812.2 NM_000812 gamma-aminobutyric acid (GABA) A receptor, beta 1 GABRB1 2560 NM_000812 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005253 // anion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // inferred from electronic annotation 207011_s_at NM_002821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002821.1 /DEF=Homo sapiens PTK7 protein tyrosine kinase 7 (PTK7), mRNA. /FEA=mRNA /GEN=PTK7 /PROD=PTK7 protein tyrosine kinase 7 /DB_XREF=gi:4506272 /UG=Hs.90572 PTK7 protein tyrosine kinase 7 /FL=gb:U33635.1 gb:U40271.1 gb:NM_002821.1 NM_002821 protein tyrosine kinase 7 PTK7 5754 NM_001270398 /// NM_002821 /// NM_152880 /// NM_152881 /// NM_152882 /// NM_152883 /// NR_072997 /// NR_072998 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003401 // axis elongation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0045198 // establishment of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0060026 // convergent extension // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207012_at U79292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79292.1 /DEF=Human clone 23734 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710273 /UG=Hs.90800 matrix metalloproteinase 16 (membrane-inserted) /FL=gb:D83646.1 gb:NM_005941.2 gb:D85511.1 gb:AB009303.1 U79292 matrix metallopeptidase 16 (membrane-inserted) MMP16 4325 NM_005941 /// NM_022564 /// NM_032297 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207013_s_at AB009303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009303.1 /DEF=Homo sapiens mRNA for membrane-type matrix metalloproteinase 3, complete cds. /FEA=mRNA /PROD=membrane-type matrix metalloproteinase 3 /DB_XREF=gi:2662305 /UG=Hs.90800 matrix metalloproteinase 16 (membrane-inserted) /FL=gb:D83646.1 gb:NM_005941.2 gb:D85511.1 gb:AB009303.1 AB009303 matrix metallopeptidase 16 (membrane-inserted) MMP16 4325 NM_005941 /// NM_022564 /// NM_032297 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207014_at NM_000807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000807.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), mRNA. /FEA=mRNA /GEN=GABRA2 /PROD=gamma-aminobutyric acid A receptor, alpha 2precursor /DB_XREF=gi:4557600 /UG=Hs.91343 gamma-aminobutyric acid (GABA) A receptor, alpha 2 /FL=gb:NM_000807.1 NM_000807 gamma-aminobutyric acid (GABA) A receptor, alpha 2 GABRA2 2555 NM_000807 /// NM_001114175 /// NM_001286827 /// XM_005248080 /// XM_006714002 0001505 // regulation of neurotransmitter levels // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // inferred from mutant phenotype 207015_s_at NM_003888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003888.1 /DEF=Homo sapiens retinaldehyde dehydrogenase 2 (RALDH2), mRNA. /FEA=mRNA /GEN=RALDH2 /PROD=retinaldehyde dehydrogenase 2 /DB_XREF=gi:10835044 /UG=Hs.95197 aldehyde dehydrogenase 1 family, member A2 /FL=gb:NM_003888.1 gb:AB015226.1 gb:AB015227.1 gb:AB015228.1 NM_003888 aldehyde dehydrogenase 1 family, member A2 ALDH1A2 8854 NM_001206897 /// NM_003888 /// NM_170696 /// NM_170697 0001568 // blood vessel development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001936 // regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006776 // vitamin A metabolic process // non-traceable author statement /// 0007494 // midgut development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009855 // determination of bilateral symmetry // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0021915 // neural tube development // inferred from mutant phenotype /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from sequence or structural similarity /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0042904 // 9-cis-retinoic acid biosynthetic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001758 // retinal dehydrogenase activity // inferred from sequence or structural similarity /// 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016918 // retinal binding // inferred from sequence or structural similarity 207016_s_at AB015228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB015228.1 /DEF=Homo sapiens mRNA for RALDH2-T, complete cds. /FEA=mRNA /GEN=RALDH2 /PROD=RALDH2-T /DB_XREF=gi:3970845 /UG=Hs.95197 aldehyde dehydrogenase 1 family, member A2 /FL=gb:NM_003888.1 gb:AB015226.1 gb:AB015227.1 gb:AB015228.1 AB015228 aldehyde dehydrogenase 1 family, member A2 /// uncharacterized LOC101928635 ALDH1A2 /// LOC101928635 8854 /// 101928635 NM_001206897 /// NM_003888 /// NM_170696 /// NM_170697 /// XR_243155 /// XR_243156 /// XR_248125 /// XR_253379 /// XR_253380 0001568 // blood vessel development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001936 // regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006776 // vitamin A metabolic process // non-traceable author statement /// 0007494 // midgut development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009855 // determination of bilateral symmetry // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0021915 // neural tube development // inferred from mutant phenotype /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from sequence or structural similarity /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0042904 // 9-cis-retinoic acid biosynthetic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001758 // retinal dehydrogenase activity // inferred from sequence or structural similarity /// 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016918 // retinal binding // inferred from sequence or structural similarity 207017_at NM_004163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004163.2 /DEF=Homo sapiens RAB27B, member RAS oncogene family (RAB27B), mRNA. /FEA=mRNA /GEN=RAB27B /PROD=RAB27B, member RAS oncogene family /DB_XREF=gi:5729996 /UG=Hs.97189 RAB27B, member RAS oncogene family /FL=gb:AF329499.1 gb:U57093.2 gb:NM_004163.2 NM_004163 RAB27B, member RAS oncogene family RAB27B 5874 NM_004163 /// XM_005266733 /// XM_005266734 /// XM_006722518 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 207018_s_at NM_004163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004163.2 /DEF=Homo sapiens RAB27B, member RAS oncogene family (RAB27B), mRNA. /FEA=mRNA /GEN=RAB27B /PROD=RAB27B, member RAS oncogene family /DB_XREF=gi:5729996 /UG=Hs.97189 RAB27B, member RAS oncogene family /FL=gb:AF329499.1 gb:U57093.2 gb:NM_004163.2 NM_004163 RAB27B, member RAS oncogene family RAB27B 5874 NM_004163 /// XM_005266733 /// XM_005266734 /// XM_006722518 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 207019_s_at NM_003886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003886.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 4 (AKAP4), mRNA. /FEA=mRNA /GEN=AKAP4 /PROD=A kinase (PRKA) anchor protein 4 /DB_XREF=gi:4502016 /UG=Hs.97633 A kinase (PRKA) anchor protein 4 /FL=gb:NM_003886.1 NM_003886 A kinase (PRKA) anchor protein 4 AKAP4 8852 NM_003886 /// NM_139289 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030317 // sperm motility // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097228 // sperm principal piece // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from sequence or structural similarity 207020_at NM_007031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007031.1 /DEF=Homo sapiens heat shock transcription factor 2 binding protein (HSF2BP), mRNA. /FEA=mRNA /GEN=HSF2BP /PROD=heat shock transcription factor 2 bindingprotein /DB_XREF=gi:5901979 /UG=Hs.97624 heat shock transcription factor 2 binding protein /FL=gb:BC000153.2 gb:AB007131.1 gb:NM_007031.1 NM_007031 heat shock transcription factor 2 binding protein HSF2BP 11077 NM_007031 /// XM_005261090 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005829 // cytosol // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207021_at NM_007009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007009.1 /DEF=Homo sapiens zona pellucida binding protein (SP38), mRNA. /FEA=mRNA /GEN=SP38 /PROD=zona pellucida binding protein /DB_XREF=gi:5902115 /UG=Hs.99875 zona pellucida binding protein /FL=gb:BC005223.1 gb:D17570.1 gb:NM_007009.1 NM_007009 zona pellucida binding protein ZPBP 11055 NM_001159878 /// NM_007009 0001675 // acrosome assembly // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207022_s_at NM_002301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002301.2 /DEF=Homo sapiens lactate dehydrogenase C (LDHC), transcript variant 1, mRNA. /FEA=mRNA /GEN=LDHC /PROD=lactate dehydrogenase C /DB_XREF=gi:9257229 /UG=Hs.99881 lactate dehydrogenase C /FL=gb:U13680.1 gb:NM_017448.1 gb:NM_002301.2 NM_002301 lactate dehydrogenase C LDHC 3948 NM_002301 /// NM_017448 /// XM_005252918 /// XM_005252919 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0019244 // lactate biosynthetic process from pyruvate // inferred from electronic annotation /// 0019516 // lactate oxidation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 207023_x_at NM_000421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000421.1 /DEF=Homo sapiens keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) (KRT10), mRNA. /FEA=mRNA /GEN=KRT10 /PROD=keratin 10 /DB_XREF=gi:4557696 /UG=Hs.99936 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) /FL=gb:NM_000421.1 gb:J04029.1 NM_000421 keratin 10 KRT10 3858 NM_000421 /// XM_005257343 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0030280 // structural constituent of epidermis // non-traceable author statement 207024_at NM_000751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000751.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, delta polypeptide (CHRND), mRNA. /FEA=mRNA /GEN=CHRND /PROD=nicotinic acetylcholine receptor deltapolypeptide precursor /DB_XREF=gi:4557460 /UG=Hs.99975 cholinergic receptor, nicotinic, delta polypeptide /FL=gb:NM_000751.1 NM_000751 cholinergic receptor, nicotinic, delta (muscle) CHRND 1144 NM_000751 /// NM_001256657 /// NR_046333 /// NR_046334 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from mutant phenotype /// 0050881 // musculoskeletal movement // inferred from mutant phenotype /// 0050905 // neuromuscular process // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // non-traceable author statement 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation /// 0042166 // acetylcholine binding // inferred from electronic annotation 207025_at NM_020435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020435.1 /DEF=Homo sapiens connexin46.6 (CX46.6), mRNA. /FEA=mRNA /GEN=CX46.6 /PROD=connexin46.6 /DB_XREF=gi:9966910 /UG=Hs.100072 connexin46.6 /FL=gb:NM_020435.1 NM_020435 gap junction protein, gamma 2, 47kDa GJC2 57165 NM_020435 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0005243 // gap junction channel activity // inferred from electronic annotation 207026_s_at NM_021949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021949.1 /DEF=Homo sapiens ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), mRNA. /FEA=mRNA /GEN=ATP2B3 /PROD=ATPase, Ca++ transporting, plasma membrane 3 /DB_XREF=gi:11386154 /UG=Hs.103124 ATPase, Ca++ transporting, plasma membrane 3 /FL=gb:NM_021949.1 gb:U57971.1 NM_021949 ATPase, Ca++ transporting, plasma membrane 3 ATP2B3 492 NM_001001344 /// NM_021949 /// XM_005274689 /// XM_005274690 /// XM_005274691 /// XM_005274692 /// XM_005274693 /// XM_006724823 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207027_at NM_001528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001528.1 /DEF=Homo sapiens HGF activator (HGFAC), mRNA. /FEA=mRNA /GEN=HGFAC /PROD=HGF activator /DB_XREF=gi:4504382 /UG=Hs.104 HGF activator /FL=gb:D14012.1 gb:NM_001528.1 NM_001528 HGF activator HGFAC 3083 NM_001297439 /// NM_001528 /// XM_005247966 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207028_at NM_006316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006316.1 /DEF=Homo sapiens DNA-binding transcriptional activator (NCYM), mRNA. /FEA=mRNA /GEN=NCYM /PROD=DNA-binding transcriptional activator /DB_XREF=gi:5453755 /UG=Hs.103989 DNA-binding transcriptional activator /FL=gb:NM_006316.1 NM_006316 MYCN opposite strand MYCNOS 10408 NM_006316 /// NR_026766 /// NR_110230 0007275 // multicellular organismal development // traceable author statement 207029_at NM_000899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000899.1 /DEF=Homo sapiens KIT ligand (KITLG), mRNA. /FEA=mRNA /GEN=KITLG /PROD=mast cell growth factor, isoform b, precursor /DB_XREF=gi:4505174 /UG=Hs.1048 KIT ligand /FL=gb:M59964.1 gb:NM_000899.1 NM_000899 KIT ligand KITLG 4254 NM_000899 /// NM_003994 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002763 // positive regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0030097 // hemopoiesis // non-traceable author statement /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0070668 // positive regulation of mast cell proliferation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005173 // stem cell factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 207030_s_at NM_001321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001321.1 /DEF=Homo sapiens cysteine and glycine-rich protein 2 (CSRP2), mRNA. /FEA=mRNA /GEN=CSRP2 /PROD=cysteine and glycine-rich protein 2 /DB_XREF=gi:4503100 /UG=Hs.10526 cysteine and glycine-rich protein 2 /FL=gb:BC000992.2 gb:U57646.1 gb:NM_001321.1 NM_001321 cysteine and glycine-rich protein 2 CSRP2 1466 NM_001321 /// XM_005268678 /// XM_006719258 /// XM_006719259 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207031_at NM_001189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001189.1 /DEF=Homo sapiens bagpipe homeobox (Drosophila) homolog 1 (BAPX1), mRNA. /FEA=mRNA /GEN=BAPX1 /PROD=bagpipe homeobox (Drosophila) homolog 1 /DB_XREF=gi:4502364 /UG=Hs.105941 bagpipe homeobox (Drosophila) homolog 1 /FL=gb:AF009801.1 gb:NM_001189.1 NM_001189 NK3 homeobox 2 NKX3-2 579 NM_001189 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0055123 // digestive system development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207032_s_at NM_001131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001131.1 /DEF=Homo sapiens acidic epididymal glycoprotein-like 1 (AEGL1), mRNA. /FEA=mRNA /GEN=AEGL1 /PROD=acidic epididymal glycoprotein-like 1 /DB_XREF=gi:4501982 /UG=Hs.109620 acidic epididymal glycoprotein-like 1 /FL=gb:D38451.1 gb:NM_001131.1 NM_001131 cysteine-rich secretory protein 1 CRISP1 167 NM_001131 /// NM_001205220 /// NM_170609 /// XM_006715003 0007342 // fusion of sperm to egg plasma membrane // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay 207033_at NM_005142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005142.1 /DEF=Homo sapiens gastric intrinsic factor (vitamin B synthesis) (GIF), mRNA. /FEA=mRNA /GEN=GIF /PROD=gastric intrinsic factor (vitamin B synthesis) /DB_XREF=gi:4826743 /UG=Hs.110014 gastric intrinsic factor (vitamin B synthesis) /FL=gb:NM_005142.1 gb:M63154.1 NM_005142 gastric intrinsic factor (vitamin B synthesis) GIF 2694 NM_005142 /// XM_005273910 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // not recorded /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0031419 // cobalamin binding // inferred from direct assay 207034_s_at NM_030379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030379.1 /DEF=Homo sapiens GLI-Kruppel family member GLI2 (GLI2), transcript variant 1, mRNA. /FEA=mRNA /GEN=GLI2 /PROD=GLI-Kruppel family member GLI2, isoform alpha /DB_XREF=gi:13518230 /UG=Hs.111867 GLI-Kruppel family member GLI2 /FL=gb:NM_030379.1 gb:AB007295.1 NM_030379 GLI family zinc finger 2 GLI2 2736 NM_005270 /// NM_030379 /// NM_030380 /// NM_030381 /// XM_006712422 /// XM_006712423 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from direct assay /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007418 // ventral midline development // inferred from sequence or structural similarity /// 0007442 // hindgut morphogenesis // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009913 // epidermal cell differentiation // inferred from direct assay /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from sequence or structural similarity /// 0021508 // floor plate formation // inferred from sequence or structural similarity /// 0021513 // spinal cord dorsal/ventral patterning // inferred from sequence or structural similarity /// 0021517 // ventral spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from sequence or structural similarity /// 0021775 // smoothened signaling pathway involved in ventral spinal cord interneuron specification // inferred from sequence or structural similarity /// 0021776 // smoothened signaling pathway involved in spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021938 // smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation // inferred from electronic annotation /// 0021965 // spinal cord ventral commissure morphogenesis // inferred from sequence or structural similarity /// 0021983 // pituitary gland development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035295 // tube development // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0060032 // notochord regression // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0072372 // primary cilium // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207035_at NM_003459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003459.1 /DEF=Homo sapiens solute carrier family 30 (zinc transporter), member 3 (SLC30A3), mRNA. /FEA=mRNA /GEN=SLC30A3 /PROD=solute carrier family 30 (zinc transporter),member 3 /DB_XREF=gi:4508042 /UG=Hs.111967 solute carrier family 30 (zinc transporter), member 3 /FL=gb:U76010.1 gb:NM_003459.1 NM_003459 solute carrier family 30 (zinc transporter), member 3 SLC30A3 7781 NM_003459 /// XM_005264547 /// XM_005264548 /// XM_005264549 /// XM_005264551 /// XM_006712098 /// XM_006712099 /// XM_006712100 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0051050 // positive regulation of transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0061088 // regulation of sequestering of zinc ion // inferred from direct assay /// 0071577 // zinc ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005770 // late endosome // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation /// 0015633 // zinc transporting ATPase activity // traceable author statement 207036_x_at NM_000836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000836.1 /DEF=Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2D (GRIN2D), mRNA. /FEA=mRNA /GEN=GRIN2D /PROD=N-methyl-D-aspartate receptor subunit 2Dprecursor /DB_XREF=gi:4504130 /UG=Hs.113286 glutamate receptor, ionotropic, N-methyl D-aspartate 2D /FL=gb:U77783.1 gb:NM_000836.1 NM_000836 glutamate receptor, ionotropic, N-methyl D-aspartate 2D GRIN2D 2906 NM_000836 0001964 // startle response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 207037_at NM_003839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003839.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 11a, activator of NFKB (TNFRSF11A), mRNA. /FEA=mRNA /GEN=TNFRSF11A /PROD=tumor necrosis factor receptor superfamily,member 11a, activator of NFKB /DB_XREF=gi:4507564 /UG=Hs.114676 tumor necrosis factor receptor superfamily, member 11a, activator of NFKB /FL=gb:AF018253.1 gb:NM_003839.1 NM_003839 tumor necrosis factor receptor superfamily, member 11a, NFKB activator TNFRSF11A 8792 NM_001270949 /// NM_001270950 /// NM_001270951 /// NM_001278268 /// NM_003839 /// XM_005266777 0001503 // ossification // inferred from electronic annotation /// 0002250 // adaptive immune response // inferred from mutant phenotype /// 0002548 // monocyte chemotaxis // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0048535 // lymph node development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from sequence or structural similarity /// 0071812 // positive regulation of fever generation by positive regulation of prostaglandin secretion // inferred from sequence or structural similarity /// 0071847 // TNFSF11-mediated signaling pathway // inferred from mutant phenotype /// 0071848 // positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005031 // tumor necrosis factor-activated receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207038_at NM_004694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004694.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 6 (SLC16A6), mRNA. /FEA=mRNA /GEN=SLC16A6 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 6 /DB_XREF=gi:4759117 /UG=Hs.114924 solute carrier family 16 (monocarboxylic acid transporters), member 6 /FL=gb:U79745.1 gb:NM_004694.1 NM_004694 solute carrier family 16, member 6 SLC16A6 9120 NM_001174166 /// NM_004694 /// XM_005257789 /// XM_006722169 0006810 // transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 207039_at NM_000077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000077.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) (CDKN2A), mRNA. /FEA=mRNA /GEN=CDKN2A /PROD=cyclin-dependent kinase inhibitor 2A (melanoma,p16, inhibits CDK4) /DB_XREF=gi:4502748 /UG=Hs.1174 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) /FL=gb:NM_000077.1 gb:L27211.1 NM_000077 cyclin-dependent kinase inhibitor 2A CDKN2A 1029 NM_000077 /// NM_001195132 /// NM_058195 /// NM_058196 /// NM_058197 /// XM_005251343 0000075 // cell cycle checkpoint // inferred from mutant phenotype /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001953 // negative regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from mutant phenotype /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0031648 // protein destabilization // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from mutant phenotype /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from sequence or structural similarity /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0090398 // cellular senescence // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype /// 1902510 // regulation of apoptotic DNA fragmentation // inferred from mutant phenotype /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0055105 // ubiquitin-protein transferase inhibitor activity // inferred from sequence or structural similarity /// 0097371 // MDM2/MDM4 family protein binding // inferred from physical interaction 207040_s_at NM_003932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003932.1 /DEF=Homo sapiens suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein) (ST13), mRNA. /FEA=mRNA /GEN=ST13 /PROD=progesterone receptor-associated p48 protein /DB_XREF=gi:4505562 /UG=Hs.119222 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein) /FL=gb:NM_003932.1 gb:U28918.1 NM_003932 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) ST13 6767 NM_001278589 /// NM_003932 0006457 // protein folding // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0061084 // negative regulation of protein refolding // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 207041_at NM_006610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006610.1 /DEF=Homo sapiens mannan-binding lectin serine protease 2 (MASP2), mRNA. /FEA=mRNA /GEN=MASP2 /PROD=mannan-binding lectin serine protease 2 /DB_XREF=gi:5729914 /UG=Hs.119983 mannan-binding lectin serine protease 2 /FL=gb:NM_006610.1 NM_006610 mannan-binding lectin serine peptidase 2 MASP2 10747 NM_006610 /// NM_139208 0001867 // complement activation, lectin pathway // inferred from direct assay /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001855 // complement component C4b binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 207042_at NM_004091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004091.1 /DEF=Homo sapiens E2F transcription factor 2 (E2F2), mRNA. /FEA=mRNA /GEN=E2F2 /PROD=E2F transcription factor 2 /DB_XREF=gi:4758225 /UG=Hs.121487 E2F transcription factor 2 /FL=gb:L22846.1 gb:NM_004091.1 NM_004091 E2F transcription factor 2 E2F2 1870 NM_004091 /// XM_005245748 /// XM_005245749 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction 207043_s_at NM_006934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006934.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (SLC6A9), mRNA. /FEA=mRNA /GEN=SLC6A9 /PROD=solute carrier family 6 (neurotransmittertransporter, glycine), member 9 /DB_XREF=gi:5902093 /UG=Hs.121499 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 /FL=gb:NM_006934.1 NM_006934 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 SLC6A9 6536 NM_001024845 /// NM_001261380 /// NM_006934 /// NM_201649 /// NR_048548 /// NR_048549 /// XM_006710840 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015816 // glycine transport // inferred from electronic annotation /// 0015849 // organic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005283 // sodium:amino acid symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015187 // glycine transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015375 // glycine:sodium symporter activity // traceable author statement 207044_at NM_000461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000461.1 /DEF=Homo sapiens thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2) (THRB), mRNA. /FEA=mRNA /GEN=THRB /PROD=thyroid hormone receptor, beta (avianerythroblastic leukemia viral (v-erb-a) oncogene homolog2) /DB_XREF=gi:10835122 /UG=Hs.121503 thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2) /FL=gb:NM_000461.1 gb:M26747.1 NM_000461 thyroid hormone receptor, beta THRB 7068 NM_000461 /// NM_001128176 /// NM_001128177 /// NM_001252634 /// XM_005265420 /// XM_005265421 /// XM_005265423 /// XM_005265424 /// XM_005265425 /// XM_006713317 /// XM_006713318 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay 207045_at NM_017667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017667.1 /DEF=Homo sapiens hypothetical protein FLJ20097 (FLJ20097), mRNA. /FEA=mRNA /GEN=FLJ20097 /PROD=hypothetical protein FLJ20097 /DB_XREF=gi:8923107 /UG=Hs.12244 hypothetical protein FLJ20097 /FL=gb:NM_017667.1 NM_017667 coiled-coil domain containing 132 CCDC132 55610 NM_001257998 /// NM_017667 /// NM_024553 /// XM_005250487 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 207046_at NM_003548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003548.1 /DEF=Homo sapiens H4 histone, family 2 (H4F2), mRNA. /FEA=mRNA /GEN=H4F2 /PROD=H4 histone, family 2 /DB_XREF=gi:4504322 /UG=Hs.123053 H4 histone, family 2 /FL=gb:NM_003548.1 NM_003548 histone cluster 1, H4a /// histone cluster 1, H4b /// histone cluster 1, H4c /// histone cluster 1, H4d /// histone cluster 1, H4e /// histone cluster 1, H4f /// histone cluster 1, H4h /// histone cluster 1, H4i /// histone cluster 1, H4j /// histone cluster 1, H4k /// histone cluster 1, H4l /// histone cluster 2, H4a /// histone cluster 2, H4b /// histone cluster 4, H4 HIST1H4A /// HIST1H4B /// HIST1H4C /// HIST1H4D /// HIST1H4E /// HIST1H4F /// HIST1H4H /// HIST1H4I /// HIST1H4J /// HIST1H4K /// HIST1H4L /// HIST2H4A /// HIST2H4B /// HIST4H4 8294 /// 8359 /// 8360 /// 8361 /// 8362 /// 8363 /// 8364 /// 8365 /// 8366 /// 8367 /// 8368 /// 8370 /// 121504 /// 554313 NM_001034077 /// NM_003495 /// NM_003538 /// NM_003539 /// NM_003540 /// NM_003541 /// NM_003542 /// NM_003543 /// NM_003544 /// NM_003545 /// NM_003546 /// NM_003548 /// NM_021968 /// NM_175054 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207047_s_at NM_004070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004070.1 /DEF=Homo sapiens chloride channel Ka (CLCNKA), mRNA. /FEA=mRNA /GEN=CLCNKA /PROD=chloride channel Ka /DB_XREF=gi:4758001 /UG=Hs.123123 chloride channel Ka /FL=gb:NM_004070.1 NM_004070 chloride channel, voltage-sensitive Ka /// chloride channel, voltage-sensitive Kb CLCNKA /// CLCNKB 1187 /// 1188 NM_000085 /// NM_001042704 /// NM_001165945 /// NM_001257139 /// NM_004070 /// XM_005245733 /// XM_006710069 /// XM_006710070 /// XM_006710071 /// XM_006710072 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207048_at NM_014229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014229.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11), mRNA. /FEA=mRNA /GEN=SLC6A11 /PROD=solute carrier family 6 (neurotransmittertransporter, GABA), member 11 /DB_XREF=gi:7657586 /UG=Hs.123639 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 /FL=gb:NM_014229.1 NM_014229 solute carrier family 6 (neurotransmitter transporter), member 11 SLC6A11 6538 NM_014229 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0015812 // gamma-aminobutyric acid transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0004014 // adenosylmethionine decarboxylase activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005332 // gamma-aminobutyric acid:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 207049_at NM_014191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014191.1 /DEF=Homo sapiens sodium channel, voltage gated, type VIII, alpha polypeptide (SCN8A), mRNA. /FEA=mRNA /GEN=SCN8A /PROD=sodium channel, voltage gated, type VIII, alphapolypeptide /DB_XREF=gi:7657543 /UG=Hs.124189 sodium channel, voltage gated, type VIII, alpha polypeptide /FL=gb:AB027567.1 gb:AF225988.1 gb:NM_014191.1 NM_014191 sodium channel, voltage gated, type VIII, alpha subunit SCN8A 6334 NM_001177984 /// NM_014191 /// NM_175894 /// XM_006719556 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0042552 // myelination // inferred from sequence or structural similarity /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred by curator /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0034706 // sodium channel complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005248 // voltage-gated sodium channel activity // non-traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 207050_at NM_000722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000722.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 2delta subunit 1 (CACNA2D1), mRNA. /FEA=mRNA /GEN=CACNA2D1 /PROD=calcium channel, voltage-dependent, alpha2delta subunit 1 /DB_XREF=gi:4757893 /UG=Hs.1295 calcium channel, voltage-dependent, alpha 2delta subunit 1 /FL=gb:M76559.1 gb:NM_000722.1 NM_000722 calcium channel, voltage-dependent, alpha 2/delta subunit 1 CACNA2D1 781 NM_000722 /// XM_005250570 /// XM_005250572 /// XM_005250573 /// XM_005250574 /// XM_006716118 /// XM_006716119 /// XM_006716120 /// XM_006716121 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207051_at NM_005495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005495.1 /DEF=Homo sapiens solute carrier family 17 (sodium phosphate), member 4 (SLC17A4), mRNA. /FEA=mRNA /GEN=SLC17A4 /PROD=solute carrier family 17 (sodium phosphate),member 4 /DB_XREF=gi:4885440 /UG=Hs.128827 solute carrier family 17 (sodium phosphate), member 4 /FL=gb:AB020527.1 gb:NM_005495.1 NM_005495 solute carrier family 17, member 4 SLC17A4 10050 NM_001286121 /// NM_005495 /// XM_006714946 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 207052_at NM_012206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012206.1 /DEF=Homo sapiens hepatitis A virus cellular receptor 1 (HAVCR-1), mRNA. /FEA=mRNA /GEN=HAVCR-1 /PROD=hepatitis A virus cellular receptor 1 /DB_XREF=gi:6912407 /UG=Hs.129711 hepatitis A virus cellular receptor 1 /FL=gb:AF043724.1 gb:NM_012206.1 NM_012206 hepatitis A virus cellular receptor 1 HAVCR1 26762 NM_001099414 /// NM_001173393 /// NM_012206 /// XM_006714840 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207053_at NM_021097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021097.1 /DEF=Homo sapiens solute carrier family 8 (sodiumcalcium exchanger), member 1 (SLC8A1), mRNA. /FEA=mRNA /GEN=SLC8A1 /PROD=solute carrier family 8 (sodiumcalciumexchanger), member 1 /DB_XREF=gi:10863912 /UG=Hs.129763 solute carrier family 8 (sodiumcalcium exchanger), member 1 /FL=gb:NM_021097.1 gb:M91368.1 NM_021097 solute carrier family 8 (sodium/calcium exchanger), member 1 SLC8A1 6546 NM_001112800 /// NM_001112801 /// NM_001112802 /// NM_001252624 /// NM_021097 /// XM_005264512 /// XM_005264513 /// XM_005264514 /// XM_006712080 /// XM_006712081 /// XM_006712082 /// XM_006712083 /// XM_006712084 /// XM_006712085 /// XM_006712086 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred by curator /// 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014829 // vascular smooth muscle contraction // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044557 // relaxation of smooth muscle // inferred from sequence or structural similarity /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // inferred by curator /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // traceable author statement /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071436 // sodium ion export // inferred from direct assay /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity /// 0097369 // sodium ion import // inferred from direct assay /// 1901660 // calcium ion export // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0005432 // calcium:sodium antiporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 207054_at NM_001563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001563.2 /DEF=Homo sapiens interphotoreceptor matrix proteoglycan 1 (IMPG1), mRNA. /FEA=mRNA /GEN=IMPG1 /PROD=interphotoreceptor matrix proteoglycan 1 /DB_XREF=gi:6631089 /UG=Hs.129882 interphotoreceptor matrix proteoglycan 1 /FL=gb:AF047492.2 gb:NM_001563.2 NM_001563 interphotoreceptor matrix proteoglycan 1 IMPG1 3617 NM_001282368 /// NM_001563 0007601 // visual perception // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207055_at NM_004767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004767.1 /DEF=Homo sapiens endothelin type b receptor-like protein 2 (ET(B)R-LP-2), mRNA. /FEA=mRNA /GEN=ET(B)R-LP-2 /PROD=endothelin type b receptor-like protein 2 /DB_XREF=gi:4758309 /UG=Hs.132049 endothelin type b receptor-like protein 2 /FL=gb:NM_004767.1 NM_004767 G protein-coupled receptor 37 like 1 GPR37L1 9283 NM_004767 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207056_s_at NM_004858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004858.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 8 (SLC4A8), mRNA. /FEA=mRNA /GEN=SLC4A8 /PROD=solute carrier family 4, sodium bicarbonatecotransporter, member 8 /DB_XREF=gi:4759133 /UG=Hs.132136 solute carrier family 4, sodium bicarbonate cotransporter, member 8 /FL=gb:AF069512.1 gb:NM_004858.1 NM_004858 solute carrier family 4, sodium bicarbonate cotransporter, member 8 SLC4A8 9498 NM_001039960 /// NM_001258401 /// NM_001258402 /// NM_001258403 /// NM_001267615 /// NM_004858 /// NR_047672 /// XM_006719700 /// XM_006719701 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 207057_at NM_004731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004731.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 7 (SLC16A7), mRNA. /FEA=mRNA /GEN=SLC16A7 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 7 /DB_XREF=gi:4759119 /UG=Hs.132183 solute carrier family 16 (monocarboxylic acid transporters), member 7 /FL=gb:AF058056.1 gb:NM_004731.1 NM_004731 solute carrier family 16 (monocarboxylate transporter), member 7 SLC16A7 9194 NM_001270622 /// NM_001270623 /// NM_004731 /// NR_073055 /// NR_073056 /// XM_005269231 /// XM_006719693 0006810 // transport // inferred from electronic annotation /// 0006848 // pyruvate transport // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // inferred from electronic annotation /// 0035873 // lactate transmembrane transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1901475 // pyruvate transmembrane transport // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005477 // pyruvate secondary active transmembrane transporter activity // traceable author statement /// 0015129 // lactate transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0050833 // pyruvate transmembrane transporter activity // inferred from direct assay 207058_s_at NM_004562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004562.1 /DEF=Homo sapiens Parkinson disease (autosomal recessive, juvenile) 2, parkin (PARK2), transcript variant 1, mRNA. /FEA=mRNA /GEN=PARK2 /PROD=parkin isoform 1 /DB_XREF=gi:4758883 /UG=Hs.132954 Parkinson disease (autosomal recessive, juvenile) 2, parkin /FL=gb:AB009973.1 gb:NM_004562.1 NM_004562 parkin RBR E3 ubiquitin protein ligase PARK2 5071 NM_004562 /// NM_013987 /// NM_013988 0000209 // protein polyubiquitination // inferred from direct assay /// 0000422 // mitochondrion degradation // inferred from mutant phenotype /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0032232 // negative regulation of actin filament bundle assembly // inferred from direct assay /// 0033132 // negative regulation of glucokinase activity // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070842 // aggresome assembly // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070997 // neuron death // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from genetic interaction /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction /// 0061630 // ubiquitin protein ligase activity // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 207059_at NM_006194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006194.1 /DEF=Homo sapiens paired box gene 9 (PAX9), mRNA. /FEA=mRNA /GEN=PAX9 /PROD=paired box gene 9 /DB_XREF=gi:7242166 /UG=Hs.132576 paired box gene 9 /FL=gb:BC001159.1 gb:NM_006194.1 NM_006194 paired box 9 PAX9 5083 NM_006194 /// XM_006720155 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042481 // regulation of odontogenesis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207060_at NM_001427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001427.2 /DEF=Homo sapiens engrailed homolog 2 (EN2), mRNA. /FEA=mRNA /GEN=EN2 /PROD=engrailed homolog 2 /DB_XREF=gi:7710120 /UG=Hs.134989 engrailed homolog 2 /FL=gb:NM_001427.2 NM_001427 engrailed homeobox 2 EN2 2020 NM_001427 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207061_at NM_001433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001433.1 /DEF=Homo sapiens ER to nucleus signalling 1 (ERN1), mRNA. /FEA=mRNA /GEN=ERN1 /PROD=ER to nucleus signalling 1 /DB_XREF=gi:4557568 /UG=Hs.137575 ER to nucleus signalling 1 /FL=gb:AF059198.1 gb:NM_001433.1 NM_001433 endoplasmic reticulum to nucleus signaling 1 ERN1 2081 NM_001433 /// NM_152461 /// XM_006721769 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0070055 // HAC1-type intron splice site recognition and cleavage // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from direct assay /// 0004521 // endoribonuclease activity // traceable author statement /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207062_at NM_000415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000415.1 /DEF=Homo sapiens islet amyloid polypeptide (IAPP), mRNA. /FEA=mRNA /GEN=IAPP /PROD=islet amyloid polypeptide precursor /DB_XREF=gi:4557654 /UG=Hs.142255 islet amyloid polypeptide /FL=gb:J04422.1 gb:NM_000415.1 NM_000415 islet amyloid polypeptide IAPP 3375 NM_000415 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0038192 // gastric inhibitory peptide signaling pathway // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0016519 // gastric inhibitory peptide receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 207063_at NM_018542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018542.1 /DEF=Homo sapiens hypothetical protein PRO2834 (PRO2834), mRNA. /FEA=mRNA /GEN=PRO2834 /PROD=hypothetical protein PRO2834 /DB_XREF=gi:8924209 /UG=Hs.138453 hypothetical protein PRO2834 /FL=gb:AF119903.1 gb:NM_018542.1 NM_018542 non-protein coding RNA 185 /// testis-specific transcript, Y-linked 14 (non-protein coding) NCRNA00185 /// TTTY14 55410 /// 83869 NR_001543 /// NR_001544 207064_s_at NM_009590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_009590.1 /DEF=Homo sapiens amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2, mRNA. /FEA=mRNA /GEN=AOC2 /PROD=copper containing amine oxidase isoform b /DB_XREF=gi:6806881 /UG=Hs.143102 amine oxidase, copper containing 2 (retina-specific) /FL=gb:AF081363.1 gb:NM_009590.1 NM_009590 amine oxidase, copper containing 2 (retina-specific) AOC2 314 NM_001158 /// NM_009590 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0009308 // amine metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005507 // copper ion binding // inferred from electronic annotation /// 0008131 // primary amine oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation /// 0052593 // tryptamine:oxygen oxidoreductase (deaminating) activity // inferred from electronic annotation /// 0052594 // aminoacetone:oxygen oxidoreductase(deaminating) activity // inferred from electronic annotation /// 0052595 // aliphatic-amine oxidase activity // inferred from electronic annotation /// 0052596 // phenethylamine:oxygen oxidoreductase (deaminating) activity // inferred from electronic annotation 207065_at NM_004693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004693.1 /DEF=Homo sapiens cytokeratin type II (K6HF), mRNA. /FEA=mRNA /GEN=K6HF /PROD=cytokeratin type II /DB_XREF=gi:4758617 /UG=Hs.145949 cytokeratin type II /FL=gb:NM_004693.1 NM_004693 keratin 75 KRT75 9119 NM_004693 0005622 // intracellular // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 207066_at NM_002152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002152.1 /DEF=Homo sapiens histidine-rich calcium-binding protein (HRC), mRNA. /FEA=mRNA /GEN=HRC /PROD=histidine-rich calcium-binding proteinprecursor /DB_XREF=gi:4504486 /UG=Hs.1480 histidine-rich calcium-binding protein /FL=gb:M60052.1 gb:NM_002152.1 NM_002152 histidine rich calcium binding protein HRC 3270 NM_002152 /// XR_243928 /// XR_430198 0006936 // muscle contraction // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0055074 // calcium ion homeostasis // inferred from electronic annotation 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 207067_s_at NM_002112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002112.1 /DEF=Homo sapiens histidine decarboxylase (HDC), mRNA. /FEA=mRNA /GEN=HDC /PROD=histidine decarboxylase /DB_XREF=gi:4504364 /UG=Hs.1481 histidine decarboxylase /FL=gb:M60445.1 gb:NM_002112.1 NM_002112 histidine decarboxylase HDC 3067 NM_002112 0001694 // histamine biosynthetic process // inferred from direct assay /// 0001694 // histamine biosynthetic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006547 // histidine metabolic process // traceable author statement /// 0006548 // histidine catabolic process // inferred from direct assay /// 0006548 // histidine catabolic process // traceable author statement /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042423 // catecholamine biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004398 // histidine decarboxylase activity // inferred from direct assay /// 0004398 // histidine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 207068_at NM_003408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003408.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp37 in mouse (ZFP37), mRNA. /FEA=mRNA /GEN=ZFP37 /PROD=zinc finger protein homologous to Zfp37 inmouse /DB_XREF=gi:4507962 /UG=Hs.150406 zinc finger protein homologous to Zfp37 in mouse /FL=gb:AF022158.1 gb:NM_003408.1 NM_003408 ZFP37 zinc finger protein ZFP37 7539 NM_001282515 /// NM_001282518 /// NM_003408 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207069_s_at NM_005585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005585.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 6 (MADH6), mRNA. /FEA=mRNA /GEN=MADH6 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 6 /DB_XREF=gi:5031898 /UG=Hs.153863 MAD (mothers against decapentaplegic, Drosophila) homolog 6 /FL=gb:U59914.1 gb:NM_005585.1 NM_005585 SMAD family member 6 SMAD6 4091 NM_001142861 /// NM_005585 /// NR_027654 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from direct assay /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070698 // type I activin receptor binding // inferred from direct assay 207070_at NM_002921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002921.1 /DEF=Homo sapiens retinal G protein coupled receptor (RGR), mRNA. /FEA=mRNA /GEN=RGR /PROD=retinal G protein coupled receptor /DB_XREF=gi:4506502 /UG=Hs.1544 retinal G protein coupled receptor /FL=gb:NM_002921.1 gb:U14910.1 NM_002921 retinal G protein coupled receptor RGR 5995 NM_001012720 /// NM_001012722 /// NM_002921 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009881 // photoreceptor activity // inferred from electronic annotation 207071_s_at NM_002197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002197.1 /DEF=Homo sapiens aconitase 1, soluble (ACO1), mRNA. /FEA=mRNA /GEN=ACO1 /PROD=aconitase 1 /DB_XREF=gi:8659554 /UG=Hs.154721 aconitase 1, soluble /FL=gb:NM_002197.1 NM_002197 aconitase 1, soluble ACO1 48 NM_001278352 /// NM_002197 /// XM_005251476 /// XM_006716777 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0050892 // intestinal absorption // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003994 // aconitate hydratase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0030350 // iron-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 207072_at NM_003853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003853.1 /DEF=Homo sapiens interleukin 18 receptor accessory protein (IL18RAP), mRNA. /FEA=mRNA /GEN=IL18RAP /PROD=interleukin 18 receptor accessory protein /DB_XREF=gi:4504656 /UG=Hs.158315 interleukin 18 receptor accessory protein /FL=gb:AF077346.1 gb:NM_003853.1 NM_003853 interleukin 18 receptor accessory protein IL18RAP 8807 NM_003853 /// XM_005264034 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207073_at NM_003948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003948.2 /DEF=Homo sapiens cyclin-dependent kinase-like 2 (CDC2-related kinase) (CDKL2), mRNA. /FEA=mRNA /GEN=CDKL2 /PROD=cyclin-dependent kinase-like 2 /DB_XREF=gi:10938004 /UG=Hs.158512 cyclin-dependent kinase-like 2 (CDC2-related kinase) /FL=gb:NM_003948.2 NM_003948 cyclin-dependent kinase-like 2 (CDC2-related kinase) CDKL2 8999 NM_003948 /// XM_005263335 /// XM_006714406 /// XM_006714407 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007548 // sex differentiation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207074_s_at NM_003053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003053.1 /DEF=Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), mRNA. /FEA=mRNA /GEN=SLC18A1 /PROD=solute carrier family 18 (vesicular monoamine),member 1 /DB_XREF=gi:4506986 /UG=Hs.158322 solute carrier family 18 (vesicular monoamine), member 1 /FL=gb:U39905.1 gb:NM_003053.1 NM_003053 solute carrier family 18 (vesicular monoamine transporter), member 1 SLC18A1 6570 NM_001135691 /// NM_001142324 /// NM_001142325 /// NM_003053 /// XR_247130 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred from electronic annotation /// 0015844 // monoamine transport // traceable author statement /// 0015893 // drug transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0008504 // monoamine transmembrane transporter activity // traceable author statement /// 0015238 // drug transmembrane transporter activity // inferred from electronic annotation 207075_at NM_004895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004895.1 /DEF=Homo sapiens chromosome 1 open reading frame 7 (C1ORF7), mRNA. /FEA=mRNA /GEN=C1ORF7 /PROD=chromosome 1 open reading frame 7 /DB_XREF=gi:4757727 /UG=Hs.159483 chromosome 1 open reading frame 7 /FL=gb:AF054176.1 gb:NM_004895.1 NM_004895 NLR family, pyrin domain containing 3 NLRP3 114548 NM_001079821 /// NM_001127461 /// NM_001127462 /// NM_001243133 /// NM_004895 /// NM_183395 /// XM_005273036 /// XM_005273037 /// XM_005273038 /// XM_006711733 0002674 // negative regulation of acute inflammatory response // inferred from mutant phenotype /// 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0009595 // detection of biotic stimulus // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032621 // interleukin-18 production // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044546 // NLRP3 inflammasome complex assembly // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050701 // interleukin-1 secretion // inferred from electronic annotation /// 0050713 // negative regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051259 // protein oligomerization // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042834 // peptidoglycan binding // traceable author statement 207076_s_at NM_000050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000050.1 /DEF=Homo sapiens argininosuccinate synthetase (ASS), mRNA. /FEA=mRNA /GEN=ASS /PROD=argininosuccinate synthetase /DB_XREF=gi:4557336 /UG=Hs.160786 argininosuccinate synthetase /FL=gb:NM_000050.1 NM_000050 argininosuccinate synthase 1 ASS1 445 NM_000050 /// NM_054012 /// XM_005272199 /// XM_005272200 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // inferred from mutant phenotype /// 0000050 // urea cycle // traceable author statement /// 0000052 // citrulline metabolic process // inferred from mutant phenotype /// 0000053 // argininosuccinate metabolic process // inferred from mutant phenotype /// 0006526 // arginine biosynthetic process // inferred from electronic annotation /// 0006531 // aspartate metabolic process // inferred from mutant phenotype /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 1903038 // negative regulation of leukocyte cell-cell adhesion // inferred from mutant phenotype 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004055 // argininosuccinate synthase activity // not recorded /// 0004055 // argininosuccinate synthase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from mutant phenotype /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207077_at NM_015849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015849.1 /DEF=Homo sapiens pancreatic elastase IIB (LOC51032), mRNA. /FEA=mRNA /GEN=LOC51032 /PROD=pancreatic elastase IIB /DB_XREF=gi:7705647 /UG=Hs.169234 pancreatic elastase IIB /FL=gb:M16653.1 gb:NM_015849.1 NM_015849 chymotrypsin-like elastase family, member 2B CELA2B 51032 NM_015849 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207078_at NM_005466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005466.1 /DEF=Homo sapiens RNA polymerase II transcriptional regulation mediator (Med6, S. cerevisiae, homolog of) (MED6), mRNA. /FEA=mRNA /GEN=MED6 /PROD=RNA polymerase II transcriptional regulationmediator (Med6, S. cerevisiae, homolog of) /DB_XREF=gi:4885480 /UG=Hs.167738 RNA polymerase II transcriptional regulation mediator (Med6, S. cerevisiae, homolog of) /FL=gb:U78082.1 gb:NM_005466.1 NM_005466 mediator complex subunit 6 MED6 10001 NM_001284209 /// NM_001284210 /// NM_001284211 /// NM_005466 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 207079_s_at NM_005466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005466.1 /DEF=Homo sapiens RNA polymerase II transcriptional regulation mediator (Med6, S. cerevisiae, homolog of) (MED6), mRNA. /FEA=mRNA /GEN=MED6 /PROD=RNA polymerase II transcriptional regulationmediator (Med6, S. cerevisiae, homolog of) /DB_XREF=gi:4885480 /UG=Hs.167738 RNA polymerase II transcriptional regulation mediator (Med6, S. cerevisiae, homolog of) /FL=gb:U78082.1 gb:NM_005466.1 NM_005466 mediator complex subunit 6 MED6 10001 NM_001284209 /// NM_001284210 /// NM_001284211 /// NM_005466 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction 207080_s_at NM_004160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004160.1 /DEF=Homo sapiens peptide YY (PYY), mRNA. /FEA=mRNA /GEN=PYY /PROD=peptide YY /DB_XREF=gi:4758981 /UG=Hs.169249 peptide YY /FL=gb:D13899.1 gb:NM_004160.1 NM_004160 peptide YY PYY 5697 NM_004160 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0042755 // eating behavior // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207081_s_at NM_002650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002650.1 /DEF=Homo sapiens phosphatidylinositol 4-kinase, catalytic, alpha polypeptide (PIK4CA), mRNA. /FEA=mRNA /GEN=PIK4CA /PROD=phosphatidylinositol 4-kinase, catalytic, alphapolypeptide /DB_XREF=gi:4505806 /UG=Hs.171625 phosphatidylinositol 4-kinase, catalytic, alpha polypeptide /FL=gb:NM_002650.1 gb:L36151.1 NM_002650 phosphatidylinositol 4-kinase, catalytic, alpha PI4KA 5297 NM_002650 /// NM_058004 /// XM_005261634 /// XM_005261635 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 207082_at NM_000757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000757.1 /DEF=Homo sapiens colony stimulating factor 1 (macrophage) (CSF1), mRNA. /FEA=mRNA /GEN=CSF1 /PROD=colony stimulating factor 1 (macrophage) /DB_XREF=gi:4503074 /UG=Hs.173894 colony stimulating factor 1 (macrophage) /FL=gb:NM_000757.1 gb:M27087.1 NM_000757 colony stimulating factor 1 (macrophage) CSF1 1435 NM_000757 /// NM_172210 /// NM_172211 /// NM_172212 0001503 // ossification // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0003006 // developmental process involved in reproduction // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010743 // regulation of macrophage derived foam cell differentiation // non-traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0030097 // hemopoiesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042117 // monocyte activation // non-traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042488 // positive regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060611 // mammary gland fat development // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay /// 0005157 // macrophage colony-stimulating factor receptor binding // inferred from sequence or structural similarity /// 0005157 // macrophage colony-stimulating factor receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 207083_s_at NM_017721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017721.1 /DEF=Homo sapiens hypothetical protein FLJ20241 (FLJ20241), mRNA. /FEA=mRNA /GEN=FLJ20241 /PROD=hypothetical protein FLJ20241 /DB_XREF=gi:8923216 /UG=Hs.181780 hypothetical protein FLJ20241 /FL=gb:NM_017721.1 NM_017721 coiled-coil and C2 domain containing 1A CC2D1A 54862 NM_017721 /// XM_005259972 /// XM_005259973 /// XM_005259974 /// XM_005259975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 207084_at NM_005604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005604.1 /DEF=Homo sapiens POU domain, class 3, transcription factor 2 (POU3F2), mRNA. /FEA=mRNA /GEN=POU3F2 /PROD=POU domain, class 3, transcription factor 2 /DB_XREF=gi:5031982 /UG=Hs.182505 POU domain, class 3, transcription factor 2 /FL=gb:NM_005604.1 NM_005604 POU class 3 homeobox 2 POU3F2 5454 NM_005604 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008544 // epidermis development // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021869 // forebrain ventricular zone progenitor cell division // inferred from electronic annotation /// 0021979 // hypothalamus cell differentiation // inferred from electronic annotation /// 0021985 // neurohypophysis development // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207085_x_at NM_006140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006140.1 /DEF=Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), mRNA. /FEA=mRNA /GEN=CSF2RA /PROD=colony stimulating factor 2 receptor, alpha,low-affinity (granulocyte-macrophage) /DB_XREF=gi:5453626 /UG=Hs.182378 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) /FL=gb:M73832.1 gb:NM_006140.1 NM_006140 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CSF2RA 1438 NM_001161529 /// NM_001161530 /// NM_001161531 /// NM_001161532 /// NM_006140 /// NM_172245 /// NM_172246 /// NM_172247 /// NM_172248 /// NM_172249 /// NR_027760 /// XM_006724437 /// XM_006724438 /// XM_006724439 /// XM_006724440 /// XM_006724441 /// XM_006724858 /// XM_006724859 /// XM_006724860 /// XM_006724861 /// XM_006724862 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207086_x_at NM_001474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001474.1 /DEF=Homo sapiens G antigen 4 (GAGE4), mRNA. /FEA=mRNA /GEN=GAGE4 /PROD=G antigen 4 /DB_XREF=gi:4503882 /UG=Hs.183199 G antigen 4 /FL=gb:NM_001474.1 gb:U19145.1 NM_001474 G antigen 1 /// G antigen 12B /// G antigen 12C /// G antigen 12D /// G antigen 12E /// G antigen 12F /// G antigen 12G /// G antigen 12H /// G antigen 12I /// G antigen 12J /// G antigen 13 /// G antigen 2A /// G antigen 2C /// G antigen 2D /// G antigen 2E /// G antigen 4 /// G antigen 5 /// G antigen 6 /// G antigen 7 /// G antigen 8 GAGE1 /// GAGE12B /// GAGE12C /// GAGE12D /// GAGE12E /// GAGE12F /// GAGE12G /// GAGE12H /// GAGE12I /// GAGE12J /// GAGE13 /// GAGE2A /// GAGE2C /// GAGE2D /// GAGE2E /// GAGE4 /// GAGE5 /// GAGE6 /// GAGE7 /// GAGE8 2543 /// 2574 /// 2576 /// 2577 /// 2578 /// 2579 /// 26748 /// 26749 /// 645051 /// 645073 /// 729396 /// 729408 /// 729422 /// 729428 /// 729431 /// 729442 /// 729447 /// 100008586 /// 100101629 /// 100132399 NM_001040663 /// NM_001098405 /// NM_001098406 /// NM_001098407 /// NM_001098408 /// NM_001098409 /// NM_001098410 /// NM_001098412 /// NM_001098418 /// NM_001127199 /// NM_001127200 /// NM_001127212 /// NM_001127345 /// NM_001468 /// NM_001472 /// NM_001474 /// NM_001475 /// NM_001476 /// NM_001477 /// NM_012196 /// NM_021123 /// NR_102272 /// XM_005272739 /// XM_005278009 0006968 // cellular defense response // traceable author statement 0005515 // protein binding // inferred from physical interaction 207087_x_at NM_020478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020478.1 /DEF=Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 5, mRNA. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin 1, isoform 5 /DB_XREF=gi:10947043 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_020478.1 gb:AF005213.1 NM_020478 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 207088_s_at NM_003562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003562.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 (SLC25A11), mRNA. /FEA=mRNA /GEN=SLC25A11 /PROD=solute carrier family 25 (mitochondrial carrier;oxoglutarate carrier), member 11 /DB_XREF=gi:4506996 /UG=Hs.184877 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 /FL=gb:NM_003562.1 NM_003562 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 SLC25A11 8402 NM_001165417 /// NM_001165418 /// NM_003562 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // traceable author statement /// 0015742 // alpha-ketoglutarate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015367 // oxoglutarate:malate antiporter activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 207089_at AF005213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005213.1 /DEF=Homo sapiens ankyrin 1 (ANK1) mRNA, complete cds. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin 1 /DB_XREF=gi:2843115 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_020478.1 gb:AF005213.1 AF005213 nebulin-related anchoring protein NRAP 4892 NM_001261463 /// NM_006175 /// NM_198060 /// XM_005269864 /// XM_005269865 /// XM_005269867 /// XM_006717870 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005916 // fascia adherens // inferred from sequence or structural similarity /// 0005927 // muscle tendon junction // inferred from sequence or structural similarity /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0014731 // spectrin-associated cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0003779 // actin binding // non-traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // inferred from sequence or structural similarity 207090_x_at NM_014898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014898.1 /DEF=Homo sapiens KIAA0961 protein (KIAA0961), mRNA. /FEA=mRNA /GEN=KIAA0961 /PROD=KIAA0961 protein /DB_XREF=gi:7662407 /UG=Hs.189464 KIAA0961 protein /FL=gb:AB023178.1 gb:NM_014898.1 NM_014898 ZFP30 zinc finger protein ZFP30 22835 NM_014898 /// XM_005258665 /// XM_006723087 /// XM_006723088 /// XM_006723089 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207091_at NM_002562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002562.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7), mRNA. /FEA=mRNA /GEN=P2RX7 /PROD=purinergic receptor P2X, ligand-gated ionchannel, 7 /DB_XREF=gi:4505552 /UG=Hs.193470 purinergic receptor P2X, ligand-gated ion channel, 7 /FL=gb:NM_002562.1 NM_002562 purinergic receptor P2X, ligand-gated ion channel, 7 P2RX7 5027 NM_002562 /// NM_177427 /// NR_033948 /// NR_033949 /// NR_033950 /// NR_033951 /// NR_033952 /// NR_033953 /// NR_033954 /// NR_033955 /// NR_033956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from electronic annotation /// 0006649 // phospholipid transfer to membrane // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006900 // membrane budding // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0019835 // cytolysis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from sequence or structural similarity /// 0032308 // positive regulation of prostaglandin secretion // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from direct assay /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043132 // NAD transport // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044254 // multicellular organismal protein catabolic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from sequence or structural similarity /// 0045919 // positive regulation of cytolysis // inferred from sequence or structural similarity /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation /// 0046931 // pore complex assembly // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051495 // positive regulation of cytoskeleton organization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051709 // regulation of killing of cells of other organism // non-traceable author statement /// 0051899 // membrane depolarization // inferred from direct assay /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070230 // positive regulation of lymphocyte apoptotic process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from sequence or structural similarity 0005639 // integral component of nuclear inner membrane // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0032059 // bleb // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from sequence or structural similarity /// 0001614 // purinergic nucleotide receptor activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0004931 // extracellular ATP-gated cation channel activity // inferred from direct assay /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred by curator /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0097110 // scaffold protein binding // inferred from electronic annotation 207092_at NM_000230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000230.1 /DEF=Homo sapiens leptin (murine obesity homolog) (LEP), mRNA. /FEA=mRNA /GEN=LEP /PROD=leptin precursor /DB_XREF=gi:4557714 /UG=Hs.194236 leptin (murine obesity homolog) /FL=gb:U43653.1 gb:AF008123.1 gb:NM_000230.1 gb:U18915.1 gb:D49487.1 NM_000230 leptin LEP 3952 NM_000230 /// XM_005250340 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0001890 // placenta development // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006114 // glycerol biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007260 // tyrosine phosphorylation of STAT protein // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008343 // adult feeding behavior // inferred from sequence or structural similarity /// 0009062 // fatty acid catabolic process // inferred from electronic annotation /// 0009892 // negative regulation of metabolic process // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033210 // leptin-mediated signaling pathway // inferred from electronic annotation /// 0033686 // positive regulation of luteinizing hormone secretion // inferred from electronic annotation /// 0035630 // bone mineralization involved in bone maturation // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043270 // positive regulation of ion transport // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045639 // positive regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045906 // negative regulation of vasoconstriction // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046881 // positive regulation of follicle-stimulating hormone secretion // inferred from electronic annotation /// 0048639 // positive regulation of developmental growth // inferred from direct assay /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0050901 // leukocyte tethering or rolling // inferred from electronic annotation /// 0060587 // regulation of lipoprotein lipid oxidation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070093 // negative regulation of glucagon secretion // inferred from electronic annotation /// 0071298 // cellular response to L-ascorbic acid // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 2000366 // positive regulation of STAT protein import into nucleus // inferred from electronic annotation /// 2000486 // negative regulation of glutamine transport // inferred from electronic annotation /// 2000491 // positive regulation of hepatic stellate cell activation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 207093_s_at NM_002544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002544.1 /DEF=Homo sapiens oligodendrocyte myelin glycoprotein (OMG), mRNA. /FEA=mRNA /GEN=OMG /PROD=oligodendrocyte myelin glycoprotein /DB_XREF=gi:4505502 /UG=Hs.194772 oligodendrocyte myelin glycoprotein /FL=gb:NM_002544.1 NM_002544 uncharacterized LOC101927057 /// oligodendrocyte myelin glycoprotein LOC101927057 /// OMG 4974 /// 101927057 NM_002544 /// XR_243788 /// XR_248347 /// XR_253655 0007155 // cell adhesion // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048683 // regulation of collateral sprouting of intact axon in response to injury // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 207094_at NM_000634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000634.1 /DEF=Homo sapiens interleukin 8 receptor, alpha (IL8RA), mRNA. /FEA=mRNA /GEN=IL8RA /PROD=interleukin 8 receptor, alpha /DB_XREF=gi:4504680 /UG=Hs.194778 interleukin 8 receptor, alpha /FL=gb:M68932.1 gb:NM_000634.1 gb:L19591.1 NM_000634 chemokine (C-X-C motif) receptor 1 CXCR1 3577 NM_000634 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038112 // interleukin-8-mediated signaling pathway // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004918 // interleukin-8 receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation /// 0019959 // interleukin-8 binding // inferred from physical interaction 207095_at NM_000452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000452.1 /DEF=Homo sapiens solute carrier family 10 (sodiumbile acid cotransporter family), member 2 (SLC10A2), mRNA. /FEA=mRNA /GEN=SLC10A2 /PROD=solute carrier family 10 (sodiumbile acidcotransporter family), member 2 /DB_XREF=gi:4506972 /UG=Hs.194783 solute carrier family 10 (sodiumbile acid cotransporter family), member 2 /FL=gb:U10417.1 gb:NM_000452.1 NM_000452 solute carrier family 10 (sodium/bile acid cotransporter), member 2 SLC10A2 6555 NM_000452 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0008508 // bile acid:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 207096_at NM_006512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006512.1 /DEF=Homo sapiens serum amyloid A4, constitutive (SAA4), mRNA. /FEA=mRNA /GEN=SAA4 /PROD=serum amyloid A4, constitutive /DB_XREF=gi:10835094 /UG=Hs.1955 serum amyloid A4, constitutive /FL=gb:NM_006512.1 gb:M81349.1 NM_006512 SAA2-SAA4 readthrough /// serum amyloid A4, constitutive SAA2-SAA4 /// SAA4 6291 /// 100528017 NM_001199744 /// NM_006512 0006953 // acute-phase response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // non-traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030593 // neutrophil chemotaxis // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // non-traceable author statement /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from direct assay /// 0050708 // regulation of protein secretion // non-traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050716 // positive regulation of interleukin-1 secretion // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation 207097_s_at NM_005835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005835.1 /DEF=Homo sapiens solute carrier family 17 (sodium phosphate), member 2 (SLC17A2), mRNA. /FEA=mRNA /GEN=SLC17A2 /PROD=solute carrier family 17 (sodium phosphate),member 2 /DB_XREF=gi:5031954 /UG=Hs.19710 solute carrier family 17 (sodium phosphate), member 2 /FL=gb:U90544.1 gb:NM_005835.1 NM_005835 solute carrier family 17, member 2 SLC17A2 10246 NM_001286123 /// NM_001286125 /// NM_005835 /// XM_005248784 /// XM_006714949 /// XM_006714950 /// XM_006714951 /// XM_006714952 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 207098_s_at NM_017927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017927.1 /DEF=Homo sapiens hypothetical protein FLJ20693 (FLJ20693), mRNA. /FEA=mRNA /GEN=FLJ20693 /PROD=hypothetical protein FLJ20693 /DB_XREF=gi:8923620 /UG=Hs.197877 hypothetical protein FLJ20693 /FL=gb:NM_017927.1 NM_017927 mitofusin 1 MFN1 55669 NM_017927 /// NM_033540 /// XM_005247595 /// XM_005247596 0006184 // GTP catabolic process // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207099_s_at NM_000390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000390.1 /DEF=Homo sapiens choroideremia (Rab escort protein 1) (CHM), mRNA. /FEA=mRNA /GEN=CHM /PROD=choroideremia (Rab escort protein 1) /DB_XREF=gi:9966760 /UG=Hs.2010 choroideremia (Rab escort protein 1) /FL=gb:NM_000390.1 NM_000390 choroideremia (Rab escort protein 1) CHM 1121 NM_000390 /// NM_001037312 /// NM_001145414 /// XM_006724615 0001568 // blood vessel development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from mutant phenotype /// 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from direct assay 0004663 // Rab geranylgeranyltransferase activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 207100_s_at NM_016830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016830.1 /DEF=Homo sapiens vesicle-associated membrane protein 1 (synaptobrevin 1) (VAMP1), transcript variant VAMP-1B, mRNA. /FEA=mRNA /GEN=VAMP1 /PROD=vesicle-associated membrane protein 1 isoformVAMP-1B /DB_XREF=gi:9257250 /UG=Hs.20021 vesicle-associated membrane protein 1 (synaptobrevin 1) /FL=gb:AF060538.1 gb:NM_014231.2 gb:NM_016830.1 NM_016830 vesicle-associated membrane protein 1 (synaptobrevin 1) VAMP1 6843 NM_014231 /// NM_016830 /// NM_199245 /// XM_006719011 /// XM_006719012 /// XM_006719013 /// XM_006719014 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 207101_at NM_016830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016830.1 /DEF=Homo sapiens vesicle-associated membrane protein 1 (synaptobrevin 1) (VAMP1), transcript variant VAMP-1B, mRNA. /FEA=mRNA /GEN=VAMP1 /PROD=vesicle-associated membrane protein 1 isoformVAMP-1B /DB_XREF=gi:9257250 /UG=Hs.20021 vesicle-associated membrane protein 1 (synaptobrevin 1) /FL=gb:AF060538.1 gb:NM_014231.2 gb:NM_016830.1 NM_016830 vesicle-associated membrane protein 1 (synaptobrevin 1) VAMP1 6843 NM_014231 /// NM_016830 /// NM_199245 /// XM_006719011 /// XM_006719012 /// XM_006719013 /// XM_006719014 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 207102_at NM_005989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005989.1 /DEF=Homo sapiens aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (AKR1D1), mRNA. /FEA=mRNA /GEN=AKR1D1 /PROD=aldo-keto reductase family 1, member D1 /DB_XREF=gi:5174694 /UG=Hs.201667 aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) /FL=gb:NM_005989.1 NM_005989 aldo-keto reductase family 1, member D1 AKR1D1 6718 NM_001190906 /// NM_001190907 /// NM_005989 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006707 // cholesterol catabolic process // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0008207 // C21-steroid hormone metabolic process // inferred from direct assay /// 0008209 // androgen metabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030573 // bile acid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047568 // 3-oxo-5-beta-steroid 4-dehydrogenase activity // inferred from electronic annotation /// 0047787 // delta4-3-oxosteroid 5beta-reductase activity // inferred from electronic annotation 207103_at NM_012281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012281.1 /DEF=Homo sapiens potassium voltage-gated channel, Shal-related subfamily, member 2 (KCND2), mRNA. /FEA=mRNA /GEN=KCND2 /PROD=potassium voltage-gated channel, Shal-relatedsubfamily, member 2 /DB_XREF=gi:9789986 /UG=Hs.202687 potassium voltage-gated channel, Shal-related subfamily, member 2 /FL=gb:AF121104.1 gb:AB028967.1 gb:NM_012281.1 NM_012281 potassium voltage-gated channel, Shal-related subfamily, member 2 KCND2 3751 NM_012281 /// XM_005250322 0001508 // action potential // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // non-traceable author statement 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // non-traceable author statement /// 0005250 // A-type (transient outward) potassium channel activity // not recorded /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207104_x_at NM_006669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006669.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), mRNA. /FEA=mRNA /GEN=LILRB1 /PROD=leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains), member 1 /DB_XREF=gi:5729926 /UG=Hs.204040 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 /FL=gb:U82279.1 gb:AF009220.1 gb:AF009221.1 gb:AF004230.1 gb:AF009005.1 gb:NM_006669.1 NM_006669 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 LILRB1 10859 NM_001081637 /// NM_001081638 /// NM_001081639 /// NM_001278398 /// NM_001278399 /// NM_006669 /// NR_103518 /// XM_005277047 /// XM_006726246 /// XM_006726247 /// XM_006726248 /// XM_006726249 /// XM_006726250 /// XM_006726251 /// XM_006726252 /// XM_006726281 /// XM_006726282 /// XM_006726283 /// XM_006726284 /// XM_006726285 /// XM_006726286 /// XM_006726287 /// XR_254255 /// XR_431086 /// XR_431087 /// XR_431094 /// XR_431095 /// XR_431096 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002309 // T cell proliferation involved in immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // non-traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014063 // negative regulation of serotonin secretion // inferred from direct assay /// 0031623 // receptor internalization // traceable author statement /// 0032609 // interferon-gamma production // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032945 // negative regulation of mononuclear cell proliferation // inferred from direct assay /// 0035548 // negative regulation of interferon-beta secretion // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045077 // negative regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0045953 // negative regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0046636 // negative regulation of alpha-beta T cell activation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0072643 // interferon-gamma secretion // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001180 // negative regulation of interleukin-10 secretion // inferred from direct assay /// 2001183 // negative regulation of interleukin-12 secretion // inferred from direct assay /// 2001186 // negative regulation of CD8-positive, alpha-beta T cell activation // inferred from direct assay /// 2001189 // negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from direct assay /// 2001193 // positive regulation of gamma-delta T cell activation involved in immune response // inferred from direct assay /// 2001199 // negative regulation of dendritic cell differentiation // inferred from mutant phenotype /// 2001202 // negative regulation of transforming growth factor-beta secretion // inferred from direct assay /// 2001205 // negative regulation of osteoclast development // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008157 // protein phosphatase 1 binding // inferred from physical interaction /// 0030107 // HLA-A specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0032393 // MHC class I receptor activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from mutant phenotype /// 0042288 // MHC class I protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 207105_s_at NM_005027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005027.1 /DEF=Homo sapiens phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (PIK3R2), mRNA. /FEA=mRNA /GEN=PIK3R2 /PROD=phosphoinositide-3-kinase, regulatory subunit,polypeptide 2 (p85 beta) /DB_XREF=gi:4826907 /UG=Hs.211586 phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) /FL=gb:NM_005027.1 NM_005027 phosphoinositide-3-kinase, regulatory subunit 2 (beta) PIK3R2 5296 NM_005027 /// NR_073517 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from sequence or structural similarity /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016667 // oxidoreductase activity, acting on a sulfur group of donors // inferred from mutant phenotype /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation 207106_s_at NM_002344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002344.1 /DEF=Homo sapiens leukocyte tyrosine kinase (LTK), mRNA. /FEA=mRNA /GEN=LTK /PROD=leukocyte tyrosine kinase /DB_XREF=gi:4505044 /UG=Hs.210 leukocyte tyrosine kinase /FL=gb:NM_002344.1 NM_002344 leukocyte receptor tyrosine kinase LTK 4058 NM_001135685 /// NM_002344 /// NM_206961 /// XM_005254381 /// XM_005254382 /// XM_006720505 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207107_at NM_000329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000329.1 /DEF=Homo sapiens retinal pigment epithelium-specific protein (65kD) (RPE65), mRNA. /FEA=mRNA /GEN=RPE65 /PROD=retinal pigment epithelium-specific protein(65kD) /DB_XREF=gi:4506590 /UG=Hs.2133 retinal pigment epithelium-specific protein (65kD) /FL=gb:NM_000329.1 gb:U18991.1 NM_000329 retinal pigment epithelium-specific protein 65kDa RPE65 6121 NM_000329 /// XM_006710811 0001523 // retinoid metabolic process // traceable author statement /// 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006776 // vitamin A metabolic process // traceable author statement /// 0007468 // regulation of rhodopsin gene expression // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004744 // retinal isomerase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052884 // all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity // inferred from electronic annotation /// 0052885 // all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity // inferred from electronic annotation 207108_s_at NM_015384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015384.1 /DEF=Homo sapiens IDN3 protein (IDN3), mRNA. /FEA=mRNA /GEN=IDN3 /PROD=IDN3 protein /DB_XREF=gi:7661841 /UG=Hs.225767 IDN3 protein /FL=gb:AB019602.1 gb:NM_015384.1 NM_015384 Nipped-B homolog (Drosophila) NIPBL 25836 NM_015384 /// NM_133433 /// XM_005248280 /// XM_005248282 /// XM_005248283 /// XM_006714467 /// XM_006714468 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001656 // metanephros development // non-traceable author statement /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0035261 // external genitalia morphogenesis // inferred from mutant phenotype /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from mutant phenotype /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0048638 // regulation of developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0061010 // gall bladder development // inferred from mutant phenotype /// 0061038 // uterus morphogenesis // inferred from mutant phenotype /// 0071481 // cellular response to X-ray // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070087 // chromo shadow domain binding // inferred from physical interaction 207109_at NM_014352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014352.1 /DEF=Homo sapiens POU transcription factor (OCT11), mRNA. /FEA=mRNA /GEN=OCT11 /PROD=POU transcription factor /DB_XREF=gi:7657408 /UG=Hs.227115 POU transcription factor /FL=gb:AF133895.1 gb:AF162278.1 gb:NM_014352.1 NM_014352 POU class 2 homeobox 3 POU2F3 25833 NM_001244682 /// NM_014352 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation 207110_at NM_021012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021012.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 12 (KCNJ12), mRNA. /FEA=mRNA /GEN=KCNJ12 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 12 /DB_XREF=gi:10337590 /UG=Hs.2363 potassium inwardly-rectifying channel, subfamily J, member 12 /FL=gb:NM_021012.1 gb:AF005214.1 gb:L36069.1 NM_021012 potassium inwardly-rectifying channel, subfamily J, member 12 /// potassium inwardly-rectifying channel, subfamily J, member 18 /// ATP-sensitive inward rectifier potassium channel 12-like KCNJ12 /// KCNJ18 /// LOC100996843 3768 /// 100134444 /// 100996843 NM_001194958 /// NM_021012 /// XM_003846726 /// XM_005256625 /// XM_005276919 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0006936 // muscle contraction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 207111_at NM_001974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001974.1 /DEF=Homo sapiens egf-like module containing, mucin-like, hormone receptor-like sequence 1 (EMR1), mRNA. /FEA=mRNA /GEN=EMR1 /PROD=egf-like module containing, mucin-like, hormonereceptor-like sequence 1 /DB_XREF=gi:4503564 /UG=Hs.2375 egf-like module containing, mucin-like, hormone receptor-like sequence 1 /FL=gb:NM_001974.1 NM_001974 egf-like module containing, mucin-like, hormone receptor-like 1 EMR1 2015 NM_001256252 /// NM_001256253 /// NM_001256254 /// NM_001256255 /// NM_001974 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 207112_s_at NM_002039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002039.1 /DEF=Homo sapiens GRB2-associated binding protein 1 (GAB1), mRNA. /FEA=mRNA /GEN=GAB1 /PROD=GRB2-associated binding protein 1 /DB_XREF=gi:4503850 /UG=Hs.239706 GRB2-associated binding protein 1 /FL=gb:U43885.1 gb:NM_002039.1 NM_002039 GRB2-associated binding protein 1 GAB1 2549 NM_002039 /// NM_207123 /// XM_005262881 /// XM_005262882 /// XM_006714167 /// XM_006714168 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 207113_s_at NM_000594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000594.1 /DEF=Homo sapiens tumor necrosis factor (TNF superfamily, member 2) (TNF), mRNA. /FEA=mRNA /GEN=TNF /PROD=tumor necrosis factor (cachectin) /DB_XREF=gi:10835154 /UG=Hs.241570 tumor necrosis factor (TNF superfamily, member 2) /FL=gb:NM_000594.1 NM_000594 tumor necrosis factor TNF 7124 NM_000594 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002037 // negative regulation of L-glutamate transport // inferred from electronic annotation /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from mutant phenotype /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0002876 // positive regulation of chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006927 // transformed cell apoptotic process // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009651 // response to salt stress // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0010888 // negative regulation of lipid storage // non-traceable author statement /// 0010940 // positive regulation of necrotic cell death // traceable author statement /// 0014823 // response to activity // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030730 // sequestering of triglyceride // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032741 // positive regulation of interleukin-18 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032800 // receptor biosynthetic process // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043242 // negative regulation of protein complex disassembly // inferred from direct assay /// 0043243 // positive regulation of protein complex disassembly // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from direct assay /// 0045123 // cellular extravasation // inferred from electronic annotation /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // non-traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045994 // positive regulation of translational initiation by iron // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0050901 // leukocyte tethering or rolling // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051222 // positive regulation of protein transport // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from direct assay /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060557 // positive regulation of vitamin D biosynthetic process // inferred from direct assay /// 0060559 // positive regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061048 // negative regulation of branching involved in lung morphogenesis // inferred from direct assay /// 0070265 // necrotic cell death // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // non-traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071677 // positive regulation of mononuclear cell migration // non-traceable author statement /// 0071803 // positive regulation of podosome assembly // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000010 // positive regulation of protein localization to cell surface // inferred from direct assay /// 2000343 // positive regulation of chemokine (C-X-C motif) ligand 2 production // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0055037 // recycling endosome // inferred from sequence or structural similarity 0002020 // protease binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 207114_at NM_025261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025261.1 /DEF=Homo sapiens G6C protein (G6C), mRNA. /FEA=mRNA /GEN=G6C /PROD=G6C protein /DB_XREF=gi:13376873 /UG=Hs.241586 G6C protein /FL=gb:NM_025261.1 NM_025261 lymphocyte antigen 6 complex, locus G6C LY6G6C 80740 NM_025261 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 207115_x_at NM_017643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017643.1 /DEF=Homo sapiens hypothetical protein FLJ20055 (FLJ20055), mRNA. /FEA=mRNA /GEN=FLJ20055 /PROD=hypothetical protein FLJ20055 /DB_XREF=gi:8923058 /UG=Hs.243756 hypothetical protein FLJ20055 /FL=gb:NM_017643.1 NM_017643 mbt domain containing 1 MBTD1 54799 NM_017643 /// XM_005257467 /// XM_005257468 /// XM_005257469 /// XM_005257470 /// XM_006721961 /// XM_006721962 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207116_s_at NM_014364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014364.1 /DEF=Homo sapiens glyceraldehyde-3-phosphate dehydrogenase, testis-specific (GAPDS), mRNA. /FEA=mRNA /GEN=GAPDS /PROD=glyceraldehyde-3-phosphate dehydrogenase,testis-specific /DB_XREF=gi:7657115 /UG=Hs.248017 glyceraldehyde-3-phosphate dehydrogenase, testis-specific /FL=gb:NM_014364.1 NM_014364 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic GAPDHS 26330 NM_014364 /// XM_005258732 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045821 // positive regulation of glycolytic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 207117_at NM_015852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015852.1 /DEF=Homo sapiens Krueppel-related zinc finger protein (H-plk), mRNA. /FEA=mRNA /GEN=H-plk /PROD=Krueppel-related zinc finger protein /DB_XREF=gi:7705388 /UG=Hs.250693 Krueppel-related zinc finger protein /FL=gb:M55422.1 gb:NM_015852.1 NM_015852 zinc finger protein 117 ZNF117 51351 NM_015852 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207118_s_at NM_004659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004659.1 /DEF=Homo sapiens matrix metalloproteinase 23A (MMP23A), mRNA. /FEA=mRNA /GEN=MMP23A /PROD=matrix metalloproteinase 23A /DB_XREF=gi:4758729 /UG=Hs.252876 matrix metalloproteinase 23A /FL=gb:AF056200.1 gb:NM_004659.1 NM_004659 matrix metallopeptidase 23A (pseudogene) /// matrix metallopeptidase 23B MMP23A /// MMP23B 8510 /// 8511 NM_006983 /// NR_002946 /// XM_005244810 /// XM_006710993 0000003 // reproduction // inferred from expression pattern /// 0006508 // proteolysis // inferred from direct assay 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207119_at NM_006258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006258.1 /DEF=Homo sapiens protein kinase, cGMP-dependent, type I (PRKG1), mRNA. /FEA=mRNA /GEN=PRKG1 /PROD=protein kinase, cGMP-dependent, type I /DB_XREF=gi:10835241 /UG=Hs.2689 protein kinase, cGMP-dependent, type I /FL=gb:NM_006258.1 NM_006258 protein kinase, cGMP-dependent, type I PRKG1 5592 NM_001098512 /// NM_006258 /// XM_005269970 /// XM_005269971 /// XM_005269972 0001764 // neuron migration // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0090331 // negative regulation of platelet aggregation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004692 // cGMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation 207120_at NM_022103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022103.1 /DEF=Homo sapiens hypothetical zinc finger protein FLJ14011 (FLJ14011), mRNA. /FEA=mRNA /GEN=FLJ14011 /PROD=hypothetical zinc finger protein FLJ14011 /DB_XREF=gi:11545814 /UG=Hs.269218 hypothetical zinc finger protein FLJ14011 /FL=gb:NM_022103.1 NM_022103 zinc finger protein 667 ZNF667 63934 NM_022103 /// NR_030740 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207121_s_at NM_002748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002748.1 /DEF=Homo sapiens mitogen-activated protein kinase 6 (MAPK6), mRNA. /FEA=mRNA /GEN=MAPK6 /PROD=mitogen-activated protein kinase 6 /DB_XREF=gi:4506090 /UG=Hs.271980 mitogen-activated protein kinase 6 /FL=gb:L77964.1 gb:NM_002748.1 NM_002748 mitogen-activated protein kinase 6 MAPK6 5597 NM_002748 /// XM_005254536 /// XM_005254537 /// XM_005254538 /// XM_005254539 0000165 // MAPK cascade // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207122_x_at NM_001054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001054.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (SULT1A2), mRNA. /FEA=mRNA /GEN=SULT1A2 /PROD=sulfotransferase family, cytosolic, 1A,phenol-preferring, member 2 /DB_XREF=gi:4507302 /UG=Hs.272462 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 /FL=gb:NM_001054.1 NM_001054 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 SULT1A2 6799 NM_001054 /// NM_177528 /// XM_006721076 /// XM_006721077 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009309 // amine biosynthetic process // traceable author statement /// 0018958 // phenol-containing compound metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004062 // aryl sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay 207123_s_at NM_003833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003833.2 /DEF=Homo sapiens matrilin 4 (MATN4), transcript variant 1, mRNA. /FEA=mRNA /GEN=MATN4 /PROD=matrilin 4 isoform 1 precursor /DB_XREF=gi:13699829 /UG=Hs.278489 matrilin 4 /FL=gb:NM_003833.2 NM_003833 matrilin 4 MATN4 8785 NM_003833 /// NM_030590 /// NM_030592 /// XM_005260597 /// XM_005260598 /// XM_005260599 0030198 // extracellular matrix organization // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207124_s_at NM_006578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006578.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta 5 (GNB5), mRNA. /FEA=mRNA /GEN=GNB5 /PROD=guanine nucleotide binding protein (G protein),beta 5 /DB_XREF=gi:5729851 /UG=Hs.275353 guanine nucleotide binding protein (G protein), beta 5 /FL=gb:AF017656.1 gb:NM_006578.1 NM_006578 guanine nucleotide binding protein (G protein), beta 5 GNB5 10681 NM_006578 /// NM_016194 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031682 // G-protein gamma-subunit binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 207125_at NM_013362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013362.1 /DEF=Homo sapiens zinc finger protein 225 (ZNF225), mRNA. /FEA=mRNA /GEN=ZNF225 /PROD=zinc finger protein 225 /DB_XREF=gi:7019592 /UG=Hs.279567 zinc finger protein 225 /FL=gb:AF187991.1 gb:NM_013362.1 NM_013362 zinc finger protein 225 ZNF225 7768 NM_013362 /// XM_005259222 /// XM_005259223 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207126_x_at NM_000463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000463.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A1 (UGT1A1), mRNA. /FEA=mRNA /GEN=UGT1A1 /PROD=UDP glycosyltransferase 1 family, polypeptideA1 /DB_XREF=gi:8850235 /UG=Hs.278896 UDP glycosyltransferase 1 family, polypeptide A1 /FL=gb:M57899.1 gb:NM_000463.1 NM_000463 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A10 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A10 /// UGT1A4 /// UGT1A6 /// UGT1A8 /// UGT1A9 54575 /// 54576 /// 54578 /// 54600 /// 54657 /// 54658 NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_021027 /// NM_205862 0001889 // liver development // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0001972 // retinoic acid binding // inferred by curator /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 207127_s_at NM_021644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021644.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H3 (2H9) (HNRPH3), mRNA. /FEA=mRNA /GEN=HNRPH3 /PROD=DKFZP586F0222 protein /DB_XREF=gi:11056058 /UG=Hs.279681 heterogeneous nuclear ribonucleoprotein H3 (2H9) /FL=gb:NM_021644.1 NM_021644 heterogeneous nuclear ribonucleoprotein H3 (2H9) HNRNPH3 3189 NM_012207 /// NM_021644 /// XM_005269748 /// XM_005269749 /// XM_005269751 /// XM_005269752 /// XM_005269753 /// XM_005269754 /// XM_006717816 /// XM_006717817 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207128_s_at NM_013361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013361.1 /DEF=Homo sapiens zinc finger protein 223 (ZNF223), mRNA. /FEA=mRNA /GEN=ZNF223 /PROD=zinc finger protein 223 /DB_XREF=gi:7019588 /UG=Hs.279782 zinc finger protein 223 /FL=gb:AF187989.1 gb:NM_013361.1 NM_013361 zinc finger protein 223 ZNF223 7766 NM_013361 /// XM_006723365 /// XM_006723366 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207129_at NM_007220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007220.1 /DEF=Homo sapiens carbonic anhydrase VB, mitochondrial (CA5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CA5B /PROD=carbonic anhydrase VB, mitochondrial precursor /DB_XREF=gi:6005722 /UG=Hs.283646 carbonic anhydrase VB, mitochondrial /FL=gb:AB021660.1 gb:NM_007220.1 NM_007220 carbonic anhydrase VB, mitochondrial CA5B 11238 NM_007220 /// XM_005274442 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207130_at NM_018634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018634.1 /DEF=Homo sapiens hypothetical protein PRO2893 (PRO2893), mRNA. /FEA=mRNA /GEN=PRO2893 /PROD=hypothetical protein PRO2893 /DB_XREF=gi:8924214 /UG=Hs.283072 hypothetical protein PRO2893 /FL=gb:AF116716.1 gb:NM_018634.1 NM_018634 zinc finger, MYND-type containing 8 ZMYND8 23613 NM_001281769 /// NM_001281771 /// NM_001281772 /// NM_001281773 /// NM_001281774 /// NM_001281775 /// NM_001281776 /// NM_001281777 /// NM_001281778 /// NM_001281779 /// NM_001281780 /// NM_001281781 /// NM_001281782 /// NM_001281783 /// NM_001281784 /// NM_012408 /// NM_183047 /// NM_183048 /// XM_005260356 /// XM_005260358 /// XM_005260360 /// XM_005260361 /// XM_005260362 /// XM_005260364 /// XM_005260365 /// XM_005260366 /// XM_005260369 /// XM_005260371 /// XM_005260377 /// XM_006723760 /// XM_006723761 /// XM_006723762 /// XM_006723763 /// XM_006723764 /// XM_006723765 /// XM_006723766 /// XM_006723767 /// XM_006723768 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity 207131_x_at NM_013430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013430.1 /DEF=Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 3, mRNA. /FEA=mRNA /GEN=GGT1 /PROD=gamma-glutamyltransferase 1 /DB_XREF=gi:9845492 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:M24903.1 gb:NM_005265.1 gb:NM_013430.1 NM_013430 gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 2 /// gamma-glutamyltransferase light chain 1 /// gamma-glutamyltransferase light chain 2 GGT1 /// GGT2 /// GGTLC1 /// GGTLC2 2678 /// 91227 /// 92086 /// 728441 NM_001032364 /// NM_001032365 /// NM_001282879 /// NM_001288833 /// NM_005265 /// NM_013421 /// NM_013430 /// NM_080839 /// NM_080920 /// NM_178311 /// NM_178312 /// NM_199127 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_005261888 /// XM_005261890 /// XM_006723661 /// XM_006723662 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 /// XM_006724392 /// XM_006724393 /// XM_006724394 /// XM_006724395 /// XM_006724396 /// XM_006724397 /// XM_006726820 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from mutant phenotype /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // inferred from direct assay /// 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay 207132_x_at NM_002624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002624.1 /DEF=Homo sapiens prefoldin 5 (PFDN5), mRNA. /FEA=mRNA /GEN=PFDN5 /PROD=prefoldin 5 /DB_XREF=gi:4505742 /UG=Hs.288856 prefoldin 5 /FL=gb:D89667.1 gb:NM_002624.1 NM_002624 prefoldin subunit 5 PFDN5 5204 NM_002624 /// NM_145896 /// NM_145897 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0016272 // prefoldin complex // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 207133_x_at NM_025144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025144.1 /DEF=Homo sapiens hypothetical protein FLJ22670 (FLJ22670), mRNA. /FEA=mRNA /GEN=FLJ22670 /PROD=hypothetical protein FLJ22670 /DB_XREF=gi:13376730 /UG=Hs.288917 hypothetical protein FLJ22670 /FL=gb:NM_025144.1 NM_025144 alpha-kinase 1 ALPK1 80216 NM_001102406 /// NM_001253884 /// NM_025144 /// XM_005263245 /// XM_005263246 /// XM_005263247 /// XM_005263248 /// XM_006714326 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207134_x_at NM_024164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024164.2 /DEF=Homo sapiens tryptase beta 2 (TPSB2), mRNA. /FEA=mRNA /GEN=TPSB2 /PROD=tryptase beta 2 precursor /DB_XREF=gi:13775596 /UG=Hs.294158 tryptase beta 2 /FL=gb:NM_024164.2 NM_024164 tryptase beta 2 (gene/pseudogene) TPSB2 64499 NM_024164 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207135_at NM_000621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000621.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A), mRNA. /FEA=mRNA /GEN=HTR2A /PROD=5-hydroxytryptamine (serotonin) receptor 2A /DB_XREF=gi:10835174 /UG=Hs.298623 5-hydroxytryptamine (serotonin) receptor 2A /FL=gb:NM_000621.1 NM_000621 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled HTR2A 3356 NM_000621 /// NM_001165947 0001659 // temperature homeostasis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007208 // phospholipase C-activating serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from electronic annotation /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046883 // regulation of hormone secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0070852 // cell body fiber // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051378 // serotonin binding // inferred from direct assay /// 0071886 // 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding // inferred from direct assay 207136_at NM_004312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004312.1 /DEF=Homo sapiens arrestin 3, retinal (X-arrestin) (ARR3), mRNA. /FEA=mRNA /GEN=ARR3 /PROD=arrestin 3, retinal (X-arrestin) /DB_XREF=gi:4757775 /UG=Hs.308 arrestin 3, retinal (X-arrestin) /FL=gb:AF033105.1 gb:U03626.1 gb:NM_004312.1 NM_004312 arrestin 3, retinal (X-arrestin) ARR3 407 NM_004312 /// XM_006724651 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0045202 // synapse // inferred from electronic annotation 0002046 // opsin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation 207137_at NM_013432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013432.1 /DEF=Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 (NFKBIL2), mRNA. /FEA=mRNA /GEN=NFKBIL2 /PROD=nuclear factor of kappa light polypeptide geneenhancer in B-cells inhibitor-like 2 /DB_XREF=gi:7305310 /UG=Hs.323834 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 /FL=gb:NM_013432.1 gb:U16258.1 NM_013432 tonsoku-like, DNA repair protein TONSL 4796 NM_013432 /// XM_005272321 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035101 // FACT complex // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0043596 // nuclear replication fork // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 207138_at NM_005392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005392.1 /DEF=Homo sapiens PHD finger protein 2 (PHF2), mRNA. /FEA=mRNA /GEN=PHF2 /PROD=PHD finger protein 2 /DB_XREF=gi:4885546 /UG=Hs.323835 PHD finger protein 2 /FL=gb:AF043725.1 gb:NM_005392.1 NM_005392 PHD finger protein 2 PHF2 5253 NM_005392 /// NM_024517 /// XM_005252051 /// XM_006717143 0001889 // liver development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006482 // protein demethylation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061188 // negative regulation of chromatin silencing at rDNA // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 207139_at NM_000704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000704.1 /DEF=Homo sapiens ATPase, H+K+ exchanging, alpha polypeptide (ATP4A), mRNA. /FEA=mRNA /GEN=ATP4A /PROD=ATPase, H+K+ exchanging, alpha polypeptide /DB_XREF=gi:4502290 /UG=Hs.36992 ATPase, H+K+ exchanging, alpha polypeptide /FL=gb:NM_000704.1 NM_000704 ATPase, H+/K+ exchanging, alpha polypeptide ATP4A 495 NM_000704 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0010155 // regulation of proton transport // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0045851 // pH reduction // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008900 // hydrogen:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207140_at NM_001631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001631.2 /DEF=Homo sapiens alkaline phosphatase, intestinal (ALPI), mRNA. /FEA=mRNA /GEN=ALPI /PROD=intestinal alkaline phosphatase precursor /DB_XREF=gi:13787191 /UG=Hs.37009 alkaline phosphatase, intestinal /FL=gb:NM_001631.2 gb:M15694.1 NM_001631 alkaline phosphatase, intestinal ALPI 248 NM_001631 /// XR_241303 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0002020 // protease binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // inferred from sequence or structural similarity /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207141_s_at U39196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39196.1 /DEF=Human clone hGIRK1 G-protein coupled inwardly rectifying potassium channel mRNA, complete cds. /FEA=mRNA /PROD=G-protein coupled inwardly rectifying potassiumchannel /DB_XREF=gi:1055027 /UG=Hs.37169 potassium inwardly-rectifying channel, subfamily J, member 3 /FL=gb:U39196.1 gb:U50964.1 gb:NM_002239.1 U39196 potassium inwardly-rectifying channel, subfamily J, member 3 KCNJ3 3760 NM_001260508 /// NM_001260509 /// NM_001260510 /// NM_002239 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation 207142_at NM_002239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002239.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 3 (KCNJ3), mRNA. /FEA=mRNA /GEN=KCNJ3 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 3 /DB_XREF=gi:4504838 /UG=Hs.37169 potassium inwardly-rectifying channel, subfamily J, member 3 /FL=gb:U39196.1 gb:U50964.1 gb:NM_002239.1 NM_002239 potassium inwardly-rectifying channel, subfamily J, member 3 KCNJ3 3760 NM_001260508 /// NM_001260509 /// NM_001260510 /// NM_002239 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation 207143_at NM_001259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001259.1 /DEF=Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA. /FEA=mRNA /GEN=CDK6 /PROD=cyclin-dependent kinase 6 /DB_XREF=gi:4502740 /UG=Hs.38481 cyclin-dependent kinase 6 /FL=gb:NM_001259.1 NM_001259 cyclin-dependent kinase 6 CDK6 1021 NM_001145306 /// NM_001259 /// XM_006715835 /// XM_006715836 0000080 // mitotic G1 phase // inferred from expression pattern /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021670 // lateral ventricle development // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043697 // cell dedifferentiation // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // traceable author statement /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045646 // regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 2000145 // regulation of cell motility // inferred from sequence or structural similarity /// 2000773 // negative regulation of cellular senescence // inferred from direct assay 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 207144_s_at NM_004143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004143.1 /DEF=Homo sapiens Cbpp300-interacting transactivator, with GluAsp-rich carboxy-terminal domain, 1 (CITED1), mRNA. /FEA=mRNA /GEN=CITED1 /PROD=Cbpp300-interacting transactivator, withGluAsp-rich carboxy-terminal domain, 1 /DB_XREF=gi:4758735 /UG=Hs.40403 Cbpp300-interacting transactivator, with GluAsp-rich carboxy-terminal domain, 1 /FL=gb:U65092.1 gb:NM_004143.1 NM_004143 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 CITED1 4435 NM_001144885 /// NM_001144886 /// NM_001144887 /// NM_004143 /// XM_005262266 /// XM_005262267 0000578 // embryonic axis specification // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001656 // metanephros development // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // traceable author statement /// 0030318 // melanocyte differentiation // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042438 // melanin biosynthetic process // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0043627 // response to estrogen // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // traceable author statement /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from sequence or structural similarity /// 0070669 // response to interleukin-2 // inferred from sequence or structural similarity /// 0070670 // response to interleukin-4 // inferred from sequence or structural similarity /// 0070741 // response to interleukin-6 // inferred from sequence or structural similarity /// 0071104 // response to interleukin-9 // inferred from sequence or structural similarity /// 0071105 // response to interleukin-11 // inferred from sequence or structural similarity /// 0071107 // response to parathyroid hormone // inferred from sequence or structural similarity /// 0071559 // response to transforming growth factor beta // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0050693 // LBD domain binding // inferred from direct assay /// 0070410 // co-SMAD binding // inferred from physical interaction 207145_at NM_005259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005259.1 /DEF=Homo sapiens growth differentiation factor 8 (GDF8), mRNA. /FEA=mRNA /GEN=GDF8 /PROD=growth differentiation factor 8 /DB_XREF=gi:4885258 /UG=Hs.41565 growth differentiation factor 8 /FL=gb:AF019627.1 gb:AF104922.1 gb:NM_005259.1 NM_005259 myostatin MSTN 2660 NM_005259 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0014741 // negative regulation of muscle hypertrophy // inferred from electronic annotation /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048632 // negative regulation of skeletal muscle tissue growth // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 207146_at NM_002278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002278.1 /DEF=Homo sapiens keratin, hair, acidic,2 (KRTHA2), mRNA. /FEA=mRNA /GEN=KRTHA2 /PROD=type I hair keratin 2 /DB_XREF=gi:4504922 /UG=Hs.41752 keratin, hair, acidic,2 /FL=gb:NM_002278.1 NM_002278 keratin 32 KRT32 3882 NM_002278 0008544 // epidermis development // traceable author statement 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207147_at NM_004405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004405.2 /DEF=Homo sapiens distal-less homeo box 2 (DLX2), mRNA. /FEA=mRNA /GEN=DLX2 /PROD=distal-less homeo box 2 /DB_XREF=gi:6996003 /UG=Hs.419 distal-less homeo box 2 /FL=gb:NM_004405.2 NM_004405 distal-less homeobox 2 DLX2 1746 NM_004405 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0021544 // subpallium development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021882 // regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from electronic annotation /// 0021893 // cerebral cortex GABAergic interneuron fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207148_x_at NM_016599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016599.1 /DEF=Homo sapiens calcineurin-binding protein calsarcin-1 (CS-1), mRNA. /FEA=mRNA /GEN=CS-1 /PROD=calcineurin-binding protein calsarcin-1 /DB_XREF=gi:7706594 /UG=Hs.42346 calcineurin-binding protein calsarcin-1 /FL=gb:AF249873.1 gb:NM_016599.1 NM_016599 myozenin 2 MYOZ2 51778 NM_016599 /// XM_006714234 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // non-traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030346 // protein phosphatase 2B binding // non-traceable author statement /// 0031433 // telethonin binding // inferred from physical interaction 207149_at L33477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L33477.1 /DEF=Human (clone 8B1) Br-cadherin mRNA, complete cds. /FEA=mRNA /PROD=Br-cadherin /DB_XREF=gi:793942 /UG=Hs.44898 cadherin 12, type 2 (N-cadherin 2) /FL=gb:NM_004061.1 gb:L34057.1 gb:L33477.1 L33477 cadherin 12, type 2 (N-cadherin 2) CDH12 1010 NM_004061 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207150_at NM_003055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003055.1 /DEF=Homo sapiens solute carrier family 18 (vesicular acetylcholine), member 3 (SLC18A3), mRNA. /FEA=mRNA /GEN=SLC18A3 /PROD=solute carrier family 18 (vesicularacetylcholine), member 3 /DB_XREF=gi:4506990 /UG=Hs.459 solute carrier family 18 (vesicular acetylcholine), member 3 /FL=gb:NM_003055.1 gb:U09210.1 NM_003055 solute carrier family 18 (vesicular acetylcholine transporter), member 3 SLC18A3 6572 NM_003055 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0015870 // acetylcholine transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement 0005277 // acetylcholine transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 207151_at NM_001118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001118.1 /DEF=Homo sapiens adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (ADCYAP1R1), mRNA. /FEA=mRNA /GEN=ADCYAP1R1 /PROD=type I adenylate cyclase activating polypeptidereceptor precursor /DB_XREF=gi:4501922 /UG=Hs.4748 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I /FL=gb:NM_001118.1 gb:D17516.1 NM_001118 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I ADCYAP1R1 117 NM_001118 /// NM_001199635 /// NM_001199636 /// NM_001199637 /// XM_005249618 /// XM_006715645 /// XM_006715646 /// XM_006715647 /// XM_006715648 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004999 // vasoactive intestinal polypeptide receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0030306 // ADP-ribosylation factor binding // inferred from electronic annotation /// 0042923 // neuropeptide binding // inferred from electronic annotation 207152_at NM_006180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006180.1 /DEF=Homo sapiens neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), mRNA. /FEA=mRNA /GEN=NTRK2 /PROD=neurotrophic tyrosine kinase, receptor, type 2 /DB_XREF=gi:5453811 /UG=Hs.47860 neurotrophic tyrosine kinase, receptor, type 2 /FL=gb:U12140.1 gb:NM_006180.1 NM_006180 neurotrophic tyrosine kinase, receptor, type 2 NTRK2 4915 NM_001007097 /// NM_001018064 /// NM_001018065 /// NM_001018066 /// NM_001291937 /// NM_006180 /// XM_005252001 /// XM_005252003 /// XM_005252004 /// XM_005252006 /// XM_005252007 /// XM_006717120 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from electronic annotation /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043121 // neurotrophin binding // inferred from direct assay /// 0043121 // neurotrophin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0048403 // brain-derived neurotrophic factor binding // inferred from sequence or structural similarity /// 0060175 // brain-derived neurotrophic factor-activated receptor activity // inferred from mutant phenotype 207153_s_at NM_007070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007070.1 /DEF=Homo sapiens FKBP-associated protein (FAP48), mRNA. /FEA=mRNA /GEN=FAP48 /PROD=FKBP-associated protein /DB_XREF=gi:5901949 /UG=Hs.49105 FKBP-associated protein /FL=gb:U73704.1 gb:NM_007070.1 NM_007070 glomulin, FKBP associated protein GLMN 11146 NM_007070 /// NM_053274 /// XM_005270400 /// XM_005270401 /// XM_006710309 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from genetic interaction /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042692 // muscle cell differentiation // inferred from mutant phenotype /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0050715 // positive regulation of cytokine secretion // inferred from mutant phenotype /// 0072359 // circulatory system development // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from physical interaction /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from physical interaction /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from physical interaction /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from physical interaction 0005171 // hepatocyte growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0055105 // ubiquitin-protein transferase inhibitor activity // inferred from genetic interaction 207154_at NM_001362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001362.1 /DEF=Homo sapiens deiodinase, iodothyronine, type III (DIO3), mRNA. /FEA=mRNA /GEN=DIO3 /PROD=thyroxine deiodinase type III /DB_XREF=gi:4503334 /UG=Hs.49322 deiodinase, iodothyronine, type III /FL=gb:S79854.1 gb:NM_001362.1 NM_001362 deiodinase, iodothyronine, type III DIO3 1735 NM_001362 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0033798 // thyroxine 5-deiodinase activity // inferred from electronic annotation 207155_at NM_000192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000192.1 /DEF=Homo sapiens T-box 5 (TBX5), mRNA. /FEA=mRNA /GEN=TBX5 /PROD=T-box 5 /DB_XREF=gi:4504454 /UG=Hs.50947 T-box 5 /FL=gb:U89353.1 gb:NM_000192.1 gb:AF221714.1 NM_000192 T-box 5 TBX5 6910 NM_000192 /// NM_080717 /// NM_080718 /// NM_181486 /// XM_006719582 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003218 // cardiac left ventricle formation // inferred from sequence or structural similarity /// 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0003283 // atrial septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from direct assay /// 0007507 // heart development // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010719 // negative regulation of epithelial to mesenchymal transition // traceable author statement /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060039 // pericardium development // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060980 // cell migration involved in coronary vasculogenesis // traceable author statement /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 1900117 // regulation of execution phase of apoptosis // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 207156_at NM_021064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021064.1 /DEF=Homo sapiens H2A histone family, member P (H2AFP), mRNA. /FEA=mRNA /GEN=H2AFP /PROD=H2A histone family, member P /DB_XREF=gi:10800131 /UG=Hs.51011 H2A histone family, member P /FL=gb:NM_021064.1 gb:L19778.1 NM_021064 histone cluster 1, H2ag /// histone cluster 1, H2ah /// histone cluster 1, H2ai /// histone cluster 1, H2ak /// histone cluster 1, H2al /// histone cluster 1, H2am HIST1H2AG /// HIST1H2AH /// HIST1H2AI /// HIST1H2AK /// HIST1H2AL /// HIST1H2AM 8329 /// 8330 /// 8332 /// 8336 /// 8969 /// 85235 NM_003509 /// NM_003510 /// NM_003511 /// NM_003514 /// NM_021064 /// NM_080596 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207157_s_at NM_005274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005274.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), gamma 5 (GNG5), mRNA. /FEA=mRNA /GEN=GNG5 /PROD=guanine nucleotide binding protein (G protein),gamma 5 /DB_XREF=gi:4885286 /UG=Hs.5322 guanine nucleotide binding protein (G protein), gamma 5 /FL=gb:NM_005274.1 NM_005274 guanine nucleotide binding protein (G protein), gamma 5 GNG5 2787 NM_005274 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay 207158_at NM_001644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001644.2 /DEF=Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (APOBEC1), transcript variant 1, mRNA. /FEA=mRNA /GEN=APOBEC1 /PROD=apolipoprotein B mRNA editing enzyme, catalyticpolypeptide 1, isoform 1 /DB_XREF=gi:5921993 /UG=Hs.560 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 /FL=gb:L25877.1 gb:U72891.1 gb:NM_001644.2 gb:NM_005889.1 gb:L26234.1 NM_001644 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 APOBEC1 339 NM_001644 /// NM_005889 /// XM_005253355 /// XM_005253356 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016554 // cytidine to uridine editing // traceable author statement /// 0016556 // mRNA modification // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from sequence or structural similarity /// 0090310 // negative regulation of methylation-dependent chromatin silencing // inferred from sequence or structural similarity 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207159_x_at NM_025021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025021.1 /DEF=Homo sapiens KIAA0616 protein (KIAA0616), mRNA. /FEA=mRNA /GEN=KIAA0616 /PROD=hypothetical protein FLJ14027 /DB_XREF=gi:13430881 /UG=Hs.6051 KIAA0616 protein /FL=gb:NM_025021.1 NM_025021 CREB regulated transcription coactivator 1 CRTC1 23373 NM_001098482 /// NM_015321 /// NM_025021 /// XM_005259833 /// XM_005259834 /// XM_005259835 /// XM_005259836 /// XM_006722710 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // inferred from direct assay 207160_at NM_000882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000882.1 /DEF=Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A), mRNA. /FEA=mRNA /GEN=IL12A /PROD=interleukin 12A /DB_XREF=gi:4504638 /UG=Hs.673 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) /FL=gb:M65271.1 gb:M65291.1 gb:AF101062.1 gb:NM_000882.1 gb:AF180562.1 NM_000882 interleukin 12A IL12A 3592 NM_000882 /// XM_005247435 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0009615 // response to virus // inferred from expression pattern /// 0010224 // response to UV-B // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032700 // negative regulation of interleukin-17 production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032816 // positive regulation of natural killer cell activation // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from mutant phenotype /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050671 // positive regulation of lymphocyte proliferation // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from expression pattern /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043514 // interleukin-12 complex // inferred from direct assay /// 0043514 // interleukin-12 complex // non-traceable author statement 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // traceable author statement /// 0005143 // interleukin-12 receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0042163 // interleukin-12 beta subunit binding // inferred from physical interaction /// 0045513 // interleukin-27 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 207161_at NM_014769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014769.1 /DEF=Homo sapiens KIAA0087 gene product (KIAA0087), mRNA. /FEA=mRNA /GEN=KIAA0087 /PROD=KIAA0087 gene product /DB_XREF=gi:7661895 /UG=Hs.69749 KIAA0087 gene product /FL=gb:D42038.1 gb:NM_014769.1 NM_014769 KIAA0087 KIAA0087 9808 NM_014769 /// NR_022006 207162_s_at NM_000718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000718.1 /DEF=Homo sapiens calcium channel, voltage-dependent, L type, alpha 1B subunit (CACNA1B), mRNA. /FEA=mRNA /GEN=CACNA1B /PROD=calcium channel, voltage-dependent, L type,alpha 1B subunit /DB_XREF=gi:4502522 /UG=Hs.69949 calcium channel, voltage-dependent, L type, alpha 1B subunit /FL=gb:M94172.1 gb:NM_000718.1 NM_000718 calcium channel, voltage-dependent, N type, alpha 1B subunit CACNA1B 774 NM_000718 /// NM_001243812 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207163_s_at NM_005163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005163.1 /DEF=Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), mRNA. /FEA=mRNA /GEN=AKT1 /PROD=serinethreonine protein kinase /DB_XREF=gi:4885060 /UG=Hs.71816 v-akt murine thymoma viral oncogene homolog 1 /FL=gb:M63167.1 gb:NM_005163.1 NM_005163 v-akt murine thymoma viral oncogene homolog 1 AKT1 207 NM_001014431 /// NM_001014432 /// NM_005163 /// XM_005267401 0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0009408 // response to heat // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0030334 // regulation of cell migration // traceable author statement /// 0031018 // endocrine pancreas development // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0031999 // negative regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032094 // response to food // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from sequence or structural similarity /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034405 // response to fluid shear stress // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046777 // protein autophosphorylation // traceable author statement /// 0046889 // positive regulation of lipid biosynthetic process // inferred from mutant phenotype /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // traceable author statement /// 0060709 // glycogen cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070141 // response to UV-A // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from electronic annotation /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901976 // regulation of cell cycle checkpoint // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred by curator /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from physical interaction 207164_s_at NM_006352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006352.1 /DEF=Homo sapiens zinc finger protein 238 (ZNF238), mRNA. /FEA=mRNA /GEN=ZNF238 /PROD=zinc finger protein 238 /DB_XREF=gi:5453586 /UG=Hs.69997 zinc finger protein 238 /FL=gb:U38896.1 gb:NM_006352.1 NM_006352 zinc finger and BTB domain containing 18 ZBTB18 10472 NM_001278196 /// NM_006352 /// NM_205768 /// XM_005273006 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051302 // regulation of cell division // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207165_at NM_012485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012485.1 /DEF=Homo sapiens hyaluronan-mediated motility receptor (RHAMM) (HMMR), transcript variant 2, mRNA. /FEA=mRNA /GEN=HMMR /PROD=hyaluronan-mediated motility receptor (RHAMM) /DB_XREF=gi:7108350 /UG=Hs.72550 hyaluronan-mediated motility receptor (RHAMM) /FL=gb:NM_012485.1 NM_012485 hyaluronan-mediated motility receptor (RHAMM) HMMR 3161 NM_001142556 /// NM_001142557 /// NM_012484 /// NM_012485 0005975 // carbohydrate metabolic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005540 // hyaluronic acid binding // inferred from electronic annotation 207166_at NM_021955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021955.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (GNGT1), mRNA. /FEA=mRNA /GEN=GNGT1 /PROD=guanine nucleotide binding protein (G protein),gamma transducing activity polypeptide 1 /DB_XREF=gi:11386178 /UG=Hs.73112 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 /FL=gb:NM_021955.1 NM_021955 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 GNGT1 2792 NM_021955 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207167_at NM_004258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004258.1 /DEF=Homo sapiens immunoglobulin superfamily, member 2 (IGSF2), mRNA. /FEA=mRNA /GEN=IGSF2 /PROD=immunoglobulin superfamily, member 2 /DB_XREF=gi:4758589 /UG=Hs.74115 immunoglobulin superfamily, member 2 /FL=gb:NM_004258.1 NM_004258 CD101 molecule CD101 9398 NM_001256106 /// NM_001256109 /// NM_001256111 /// NM_004258 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 207168_s_at NM_004893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004893.1 /DEF=Homo sapiens H2A histone family, member Y (H2AFY), mRNA. /FEA=mRNA /GEN=H2AFY /PROD=H2A histone family, member Y /DB_XREF=gi:4758495 /UG=Hs.75258 H2A histone family, member Y /FL=gb:AF054174.1 gb:NM_004893.1 NM_004893 H2A histone family, member Y H2AFY 9555 NM_001040158 /// NM_004893 /// NM_138609 /// NM_138610 /// XM_005272132 /// XM_005272134 /// XM_005272135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001558 // regulation of cell growth // inferred from genetic interaction /// 0006334 // nucleosome assembly // non-traceable author statement /// 0007549 // dosage compensation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from mutant phenotype /// 0045814 // negative regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0061187 // regulation of chromatin silencing at rDNA // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from mutant phenotype /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from genetic interaction /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype /// 1902750 // negative regulation of cell cycle G2/M phase transition // inferred from mutant phenotype 0000786 // nucleosome // non-traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0001739 // sex chromatin // traceable author statement /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000182 // rDNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010385 // double-stranded methylated DNA binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207169_x_at NM_001954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001954.2 /DEF=Homo sapiens discoidin domain receptor family, member 1 (DDR1), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDR1 /PROD=discoidin receptor tyrosine kinase isoform b /DB_XREF=gi:7669486 /UG=Hs.75562 discoidin domain receptor family, member 1 /FL=gb:NM_001954.2 NM_001954 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 /// 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207170_s_at NM_015416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015416.1 /DEF=Homo sapiens DKFZP586A011 protein (DKFZP586A011), mRNA. /FEA=mRNA /GEN=DKFZP586A011 /PROD=DKFZP586A011 protein /DB_XREF=gi:7661659 /UG=Hs.75884 DKFZP586A011 protein /FL=gb:NM_015416.1 NM_015416 LETM1 domain containing 1 LETMD1 25875 NM_001024668 /// NM_001024669 /// NM_001024670 /// NM_001024671 /// NM_001243689 /// NM_015416 /// NR_045017 /// NR_045018 /// NR_045019 /// NR_045020 /// XM_006719333 /// XM_006719334 /// XM_006719335 /// XM_006719336 /// XM_006719337 /// XM_006719338 /// XM_006719339 /// XM_006719340 /// XR_429089 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207172_s_at NM_001797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001797.1 /DEF=Homo sapiens cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11), mRNA. /FEA=mRNA /GEN=CDH11 /PROD=cadherin 11, type 2, OB-cadherin (osteoblast) /DB_XREF=gi:4502716 /UG=Hs.75929 cadherin 11, type 2, OB-cadherin (osteoblast) /FL=gb:NM_001797.1 gb:L34056.1 gb:D21254.1 NM_001797 cadherin 11, type 2, OB-cadherin (osteoblast) CDH11 1009 NM_001797 /// XM_005255761 /// XM_005255762 /// XM_005255763 /// XM_005255764 /// XM_005255766 /// XM_005255767 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0021957 // corticospinal tract morphogenesis // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207173_x_at D21254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D21254.1 /DEF=Human mRNA for OB-cadherin-1, complete cds. /FEA=mRNA /GEN=osf-4 /PROD=OB-cadherin-1 /DB_XREF=gi:575577 /UG=Hs.75929 cadherin 11, type 2, OB-cadherin (osteoblast) /FL=gb:NM_001797.1 gb:L34056.1 gb:D21254.1 D21254 cadherin 11, type 2, OB-cadherin (osteoblast) CDH11 1009 NM_001797 /// XM_005255761 /// XM_005255762 /// XM_005255763 /// XM_005255764 /// XM_005255766 /// XM_005255767 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0021957 // corticospinal tract morphogenesis // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207174_at NM_004466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004466.2 /DEF=Homo sapiens glypican 5 (GPC5), mRNA. /FEA=mRNA /GEN=GPC5 /PROD=glypican 5 /DB_XREF=gi:5360214 /UG=Hs.76828 glypican 5 /FL=gb:U66033.1 gb:AF001462.1 gb:NM_004466.2 NM_004466 glypican 5 GPC5 2262 NM_004466 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 207175_at NM_004797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004797.1 /DEF=Homo sapiens adipose most abundant gene transcript 1 (APM1), mRNA. /FEA=mRNA /GEN=APM1 /PROD=adipose most abundant gene transcript 1 /DB_XREF=gi:4757759 /UG=Hs.80485 adipose most abundant gene transcript 1 /FL=gb:NM_004797.1 gb:D45371.1 NM_004797 adiponectin, C1Q and collagen domain containing ADIPOQ 9370 NM_001177800 /// NM_004797 0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006635 // fatty acid beta-oxidation // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0010739 // positive regulation of protein kinase A signaling // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010906 // regulation of glucose metabolic process // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0019395 // fatty acid oxidation // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033034 // positive regulation of myeloid cell apoptotic process // inferred from direct assay /// 0033211 // adiponectin-activated signaling pathway // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034383 // low-density lipoprotein particle clearance // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045650 // negative regulation of macrophage differentiation // inferred from direct assay /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from direct assay /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045923 // positive regulation of fatty acid metabolic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // non-traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from direct assay /// 0050805 // negative regulation of synaptic transmission // inferred from direct assay /// 0050873 // brown fat cell differentiation // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070543 // response to linoleic acid // inferred from electronic annotation /// 0070994 // detection of oxidative stress // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071639 // positive regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090317 // negative regulation of intracellular protein transport // inferred from direct assay /// 1900121 // negative regulation of receptor binding // inferred from direct assay /// 2000279 // negative regulation of DNA biosynthetic process // inferred from direct assay /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2000478 // positive regulation of metanephric glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000534 // positive regulation of renal albumin absorption // inferred from direct assay /// 2000584 // negative regulation of platelet-derived growth factor receptor-alpha signaling pathway // inferred from sequence or structural similarity /// 2000590 // negative regulation of metanephric mesenchymal cell migration // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005125 // cytokine activity // non-traceable author statement /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0033691 // sialic acid binding // inferred from direct assay /// 0042802 // identical protein binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction 207176_s_at NM_005191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005191.1 /DEF=Homo sapiens CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) (CD80), mRNA. /FEA=mRNA /GEN=CD80 /PROD=CD80 antigen (CD28 antigen ligand 1, B7-1antigen) /DB_XREF=gi:4885122 /UG=Hs.838 CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) /FL=gb:NM_005191.1 NM_005191 CD80 molecule CD80 941 NM_005191 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042110 // T cell activation // inferred by curator /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045425 // positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process // non-traceable author statement /// 0045627 // positive regulation of T-helper 1 cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement 207177_at NM_000959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000959.1 /DEF=Homo sapiens prostaglandin F receptor (FP) (PTGFR), mRNA. /FEA=mRNA /GEN=PTGFR /PROD=prostaglandin F receptor (FP) /DB_XREF=gi:4506260 /UG=Hs.89418 prostaglandin F receptor (FP) /FL=gb:AF004021.1 gb:NM_000959.1 gb:L24470.1 NM_000959 prostaglandin F receptor (FP) PTGFR 5737 NM_000959 /// NM_001039585 /// XM_006710781 /// XR_426624 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007567 // parturition // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004958 // prostaglandin F receptor activity // inferred from direct assay 207178_s_at NM_002031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002031.1 /DEF=Homo sapiens fyn-related kinase (FRK), mRNA. /FEA=mRNA /GEN=FRK /PROD=fyn-related kinase /DB_XREF=gi:4503786 /UG=Hs.89426 fyn-related kinase /FL=gb:U00803.1 gb:NM_002031.1 NM_002031 fyn-related Src family tyrosine kinase FRK 2444 NM_002031 /// XM_005266880 /// XM_005266881 /// XM_005266882 0006468 // protein phosphorylation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207179_at NM_005521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005521.1 /DEF=Homo sapiens homeo box 11 (T-cell lymphoma 3-associated breakpoint) (HOX11), mRNA. /FEA=mRNA /GEN=HOX11 /PROD=homeo box 11 (T-cell lymphoma 3-associatedbreakpoint) /DB_XREF=gi:5031756 /UG=Hs.89583 homeo box 11 (T-cell lymphoma 3-associated breakpoint) /FL=gb:M75952.1 gb:NM_005521.1 NM_005521 T-cell leukemia homeobox 1 TLX1 3195 NM_001195517 /// NM_005521 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207180_s_at NM_006410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006410.1 /DEF=Homo sapiens Tat-interacting protein (30kD) (TIP30), mRNA. /FEA=mRNA /GEN=TIP30 /PROD=Tat-interacting protein (30kD) /DB_XREF=gi:5454125 /UG=Hs.90753 Tat-interacting protein (30kD) /FL=gb:U69161.1 gb:NM_006410.1 NM_006410 HIV-1 Tat interactive protein 2, 30kDa HTATIP2 10553 NM_001098520 /// NM_001098521 /// NM_001098522 /// NM_001098523 /// NM_006410 0001525 // angiogenesis // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 207181_s_at NM_001227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001227.1 /DEF=Homo sapiens caspase 7, apoptosis-related cysteine protease (CASP7), mRNA. /FEA=mRNA /GEN=CASP7 /PROD=caspase 7, apoptosis-related cysteine protease /DB_XREF=gi:4502580 /UG=Hs.9216 caspase 7, apoptosis-related cysteine protease /FL=gb:U37448.1 gb:U40281.1 gb:U67319.1 gb:U67320.1 gb:NM_001227.1 NM_001227 caspase 7, apoptosis-related cysteine peptidase CASP7 840 NM_001227 /// NM_001267056 /// NM_001267057 /// NM_001267058 /// NM_033338 /// NM_033339 /// NM_033340 /// XM_006718016 /// XM_006718017 /// XM_006718018 /// XM_006718019 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 207182_at NM_000811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000811.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6), mRNA. /FEA=mRNA /GEN=GABRA6 /PROD=gamma-aminobutyric acid A receptor, alpha 6precursor /DB_XREF=gi:4557606 /UG=Hs.90791 gamma-aminobutyric acid (GABA) A receptor, alpha 6 /FL=gb:NM_000811.1 NM_000811 gamma-aminobutyric acid (GABA) A receptor, alpha 6 GABRA6 2559 NM_000811 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // traceable author statement 207183_at NM_006143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006143.1 /DEF=Homo sapiens G protein-coupled receptor 19 (GPR19), mRNA. /FEA=mRNA /GEN=GPR19 /PROD=G protein-coupled receptor 19 /DB_XREF=gi:5453665 /UG=Hs.92458 G protein-coupled receptor 19 /FL=gb:NM_006143.1 NM_006143 G protein-coupled receptor 19 GPR19 2842 NM_006143 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 207184_at NM_016615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016615.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, GABA), member 13 (SLC6A13), mRNA. /FEA=mRNA /GEN=SLC6A13 /PROD=solute carrier family 6 (neurotransmittertransporter, GABA), member 13 /DB_XREF=gi:7705538 /UG=Hs.96970 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 /FL=gb:U76343.2 gb:NM_016615.1 NM_016615 solute carrier family 6 (neurotransmitter transporter), member 13 SLC6A13 6540 NM_001190997 /// NM_001243392 /// NM_016615 /// XM_005253749 /// XM_006719006 /// XM_006719007 /// XM_006719008 /// XM_006719009 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0015812 // gamma-aminobutyric acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005332 // gamma-aminobutyric acid:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 207185_at NM_003049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003049.1 /DEF=Homo sapiens solute carrier family 10 (sodiumbile acid cotransporter family), member 1 (SLC10A1), mRNA. /FEA=mRNA /GEN=SLC10A1 /PROD=solute carrier family 10 (sodiumbile acidcotransporter family), member 1 /DB_XREF=gi:4506970 /UG=Hs.952 solute carrier family 10 (sodiumbile acid cotransporter family), member 1 /FL=gb:L21893.1 gb:NM_003049.1 NM_003049 solute carrier family 10 (sodium/bile acid cotransporter), member 1 SLC10A1 6554 NM_003049 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0008508 // bile acid:sodium symporter activity // inferred from electronic annotation /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 207186_s_at NM_004459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004459.2 /DEF=Homo sapiens fetal Alzheimer antigen (FALZ), mRNA. /FEA=mRNA /GEN=FALZ /PROD=fetal Alzheimer antigen /DB_XREF=gi:6552329 /UG=Hs.99872 fetal Alzheimer antigen /FL=gb:U05237.1 gb:NM_004459.2 NM_004459 bromodomain PHD finger transcription factor BPTF 2186 NM_004459 /// NM_182641 /// XM_005257150 /// XM_005257151 /// XM_005257152 /// XM_005257153 /// XM_005257154 /// XM_005257155 /// XM_005257156 /// XM_005257157 /// XM_005257158 /// XM_005257159 /// XM_005257160 /// XM_005257161 /// XM_005257162 /// XM_006721770 /// XM_006721771 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007492 // endoderm development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 207187_at NM_000215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000215.1 /DEF=Homo sapiens Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3), mRNA. /FEA=mRNA /GEN=JAK3 /PROD=Janus kinase 3 /DB_XREF=gi:4557680 /UG=Hs.99877 Janus kinase 3 (a protein tyrosine kinase, leukocyte) /FL=gb:NM_000215.1 gb:U09607.1 NM_000215 Janus kinase 3 JAK3 3718 NM_000215 /// XM_005259896 /// XM_006722745 /// XR_430137 0002376 // immune system process // inferred from electronic annotation /// 0002731 // negative regulation of dendritic cell cytokine production // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from sequence or structural similarity /// 0007260 // tyrosine phosphorylation of STAT protein // traceable author statement /// 0007262 // STAT protein import into nucleus // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0032693 // negative regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035771 // interleukin-4-mediated signaling pathway // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043029 // T cell homeostasis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045221 // negative regulation of FasL biosynthetic process // inferred from sequence or structural similarity /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070232 // regulation of T cell apoptotic process // inferred from sequence or structural similarity /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0070669 // response to interleukin-2 // traceable author statement /// 0070670 // response to interleukin-4 // inferred from direct assay /// 0070672 // response to interleukin-15 // traceable author statement /// 0071104 // response to interleukin-9 // traceable author statement /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 207188_at NM_001258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001258.1 /DEF=Homo sapiens cyclin-dependent kinase 3 (CDK3), mRNA. /FEA=mRNA /GEN=CDK3 /PROD=cyclin-dependent kinase 3 /DB_XREF=gi:4557438 /UG=Hs.100009 cyclin-dependent kinase 3 /FL=gb:NM_001258.1 NM_001258 cyclin-dependent kinase 3 /// TEN1-CDK3 readthrough (NMD candidate) CDK3 /// TEN1-CDK3 1018 /// 100529145 NM_001258 /// NR_037709 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045023 // G0 to G1 transition // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070188 // Stn1-Ten1 complex // inferred from electronic annotation /// 0070188 // Stn1-Ten1 complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207189_s_at NM_015113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015113.1 /DEF=Homo sapiens KIAA0399 protein (KIAA0399), mRNA. /FEA=mRNA /GEN=KIAA0399 /PROD=KIAA0399 protein /DB_XREF=gi:13375619 /UG=Hs.100955 KIAA0399 protein /FL=gb:NM_015113.1 NM_015113 zinc finger, ZZ-type with EF-hand domain 1 ZZEF1 23140 NM_015113 /// XM_005256560 /// XM_005256561 /// XM_005256562 /// XM_006721485 /// XM_006721486 /// XR_429813 0005509 // calcium ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207190_at NM_015113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015113.1 /DEF=Homo sapiens KIAA0399 protein (KIAA0399), mRNA. /FEA=mRNA /GEN=KIAA0399 /PROD=KIAA0399 protein /DB_XREF=gi:13375619 /UG=Hs.100955 KIAA0399 protein /FL=gb:NM_015113.1 NM_015113 zinc finger, ZZ-type with EF-hand domain 1 ZZEF1 23140 NM_015113 /// XM_005256560 /// XM_005256561 /// XM_005256562 /// XM_006721485 /// XM_006721486 /// XR_429813 0005509 // calcium ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207191_s_at NM_005545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005545.1 /DEF=Homo sapiens immunoglobulin superfamily containing leucine-rich repeat (ISLR), mRNA. /FEA=mRNA /GEN=ISLR /PROD=immunoglobulin superfamily containingleucine-rich repeat /DB_XREF=gi:5031808 /UG=Hs.102171 immunoglobulin superfamily containing leucine-rich repeat /FL=gb:AB003184.1 gb:NM_005545.1 NM_005545 immunoglobulin superfamily containing leucine-rich repeat ISLR 3671 NM_005545 /// NM_201526 0007155 // cell adhesion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 207192_at NM_001374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001374.1 /DEF=Homo sapiens deoxyribonuclease I-like 2 (DNASE1L2), mRNA. /FEA=mRNA /GEN=DNASE1L2 /PROD=deoxyribonuclease I-like 2 /DB_XREF=gi:4503346 /UG=Hs.103503 deoxyribonuclease I-like 2 /FL=gb:U62647.1 gb:NM_001374.1 NM_001374 deoxyribonuclease I-like 2 DNASE1L2 1775 NM_001374 /// XM_005255152 /// XM_006720856 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207193_at NM_001138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001138.1 /DEF=Homo sapiens agouti (mouse) related protein (AGRP), transcript variant 1, mRNA. /FEA=mRNA /GEN=AGRP /PROD=agouti (mouse) related protein /DB_XREF=gi:4501994 /UG=Hs.104633 agouti (mouse) related protein /FL=gb:U88063.1 gb:U89485.1 gb:NM_001138.1 gb:NM_007316.1 NM_001138 agouti related protein homolog (mouse) AGRP 181 NM_001138 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007631 // feeding behavior // traceable author statement /// 0008343 // adult feeding behavior // inferred from electronic annotation /// 0009648 // photoperiodism // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from direct assay /// 2000253 // positive regulation of feeding behavior // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from direct assay 207194_s_at NM_001544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001544.2 /DEF=Homo sapiens intercellular adhesion molecule 4, Landsteiner-Wiener blood group (ICAM4), transcript variant 1, mRNA. /FEA=mRNA /GEN=ICAM4 /PROD=intercellular adhesion molecule 4, isoform 1precursor /DB_XREF=gi:12545400 /UG=Hs.108287 intercellular adhesion molecule 4, Landsteiner-Wiener blood group /FL=gb:NM_001544.2 gb:L27671.1 NM_001544 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) ICAM4 3386 NM_001039132 /// NM_001544 /// NM_022377 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005178 // integrin binding // traceable author statement 207195_at NM_014461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014461.1 /DEF=Homo sapiens contactin 6 (CNTN6), mRNA. /FEA=mRNA /GEN=CNTN6 /PROD=contactin 6 /DB_XREF=gi:7657360 /UG=Hs.109050 contactin 6 /FL=gb:AB003592.1 gb:NM_014461.1 NM_014461 contactin 6 CNTN6 27255 NM_001289080 /// NM_001289081 /// NM_014461 /// XM_005265058 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207196_s_at NM_006058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006058.1 /DEF=Homo sapiens Nef-associated factor 1 (NAF1), mRNA. /FEA=mRNA /GEN=NAF1 /PROD=Nef-associated factor 1 /DB_XREF=gi:5174608 /UG=Hs.109281 Nef-associated factor 1 /FL=gb:NM_006058.1 NM_006058 TNFAIP3 interacting protein 1 TNIP1 10318 NM_001252385 /// NM_001252386 /// NM_001252390 /// NM_001252391 /// NM_001252392 /// NM_001252393 /// NM_001258454 /// NM_001258455 /// NM_001258456 /// NM_006058 /// XM_005268355 /// XM_006714751 /// XM_006714752 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0006412 // translation // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0009101 // glycoprotein biosynthetic process // inferred from direct assay /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0085032 // modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay 207197_at NM_003413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003413.1 /DEF=Homo sapiens Zic family member 3 (odd-paired Drosophila homolog, heterotaxy 1) (ZIC3), mRNA. /FEA=mRNA /GEN=ZIC3 /PROD=Zic family member 3 (odd-paired Drosophilahomolog, heterotaxy 1) /DB_XREF=gi:4507972 /UG=Hs.111227 Zic family member 3 (odd-paired Drosophila homolog, heterotaxy 1) /FL=gb:AF028706.1 gb:NM_003413.1 NM_003413 Zic family member 3 ZIC3 7547 NM_003413 0001947 // heart looping // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from mutant phenotype /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from mutant phenotype /// 0035469 // determination of pancreatic left/right asymmetry // inferred from mutant phenotype /// 0035545 // determination of left/right asymmetry in nervous system // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207198_s_at NM_004987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004987.2 /DEF=Homo sapiens LIM and senescent cell antigen-like domains 1 (LIMS1), mRNA. /FEA=mRNA /GEN=LIMS1 /PROD=LIM and senescent cell antigen-like domains 1 /DB_XREF=gi:13518025 /UG=Hs.112378 LIM and senescent cell antigen-like domains 1 /FL=gb:U09284.2 gb:NM_004987.2 NM_004987 LIM and senescent cell antigen-like domains 1 /// LIM and senescent cell antigen-like domains 3-like LIMS1 /// LIMS3L 3987 /// 100288695 NM_001193482 /// NM_001193483 /// NM_001193484 /// NM_001193485 /// NM_001193488 /// NM_001205288 /// NM_004987 /// NR_038099 /// XM_005263563 /// XM_005263946 /// XM_005263947 /// XM_005263948 /// XM_005263949 /// XM_005263950 /// XM_005263951 /// XM_006712167 /// XM_006712524 /// XR_244813 0007569 // cell aging // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207199_at NM_003219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003219.1 /DEF=Homo sapiens telomerase reverse transcriptase (TERT), mRNA. /FEA=mRNA /GEN=TERT /PROD=telomerase reverse transcriptase /DB_XREF=gi:4507438 /UG=Hs.115256 telomerase reverse transcriptase /FL=gb:AF015950.1 gb:AF018167.1 gb:NM_003219.1 NM_003219 telomerase reverse transcriptase TERT 7015 NM_001193376 /// NM_198253 /// NM_198254 /// NM_198255 /// XR_241712 /// XR_241713 0000723 // telomere maintenance // traceable author statement /// 0006278 // RNA-dependent DNA replication // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0022616 // DNA strand elongation // inferred from direct assay /// 0032203 // telomere formation via telomerase // inferred from direct assay /// 0090399 // replicative senescence // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred by curator /// 0000783 // nuclear telomere cap complex // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003720 // telomerase activity // inferred from direct assay /// 0003721 // telomeric template RNA reverse transcriptase activity // inferred from direct assay /// 0003721 // telomeric template RNA reverse transcriptase activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003964 // RNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070034 // telomeric RNA binding // inferred from direct assay 207200_at NM_000531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000531.2 /DEF=Homo sapiens ornithine carbamoyltransferase (OTC), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OTC /PROD=ornithine carbamoyltransferase precursor /DB_XREF=gi:9257233 /UG=Hs.117050 ornithine carbamoyltransferase /FL=gb:NM_000531.2 NM_000531 ornithine carbamoyltransferase OTC 5009 NM_000531 0000050 // urea cycle // inferred from direct assay /// 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006526 // arginine biosynthetic process // inferred from electronic annotation /// 0006591 // ornithine metabolic process // inferred from electronic annotation /// 0006593 // ornithine catabolic process // inferred from direct assay /// 0007494 // midgut development // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0019240 // citrulline biosynthetic process // inferred from direct assay /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055081 // anion homeostasis // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 0070781 // response to biotin // inferred from electronic annotation /// 0097272 // ammonia homeostasis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0009348 // ornithine carbamoyltransferase complex // non-traceable author statement 0004585 // ornithine carbamoyltransferase activity // not recorded /// 0004585 // ornithine carbamoyltransferase activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016743 // carboxyl- or carbamoyltransferase activity // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from electronic annotation 207201_s_at NM_003057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003057.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 1 (SLC22A1), mRNA. /FEA=mRNA /GEN=SLC22A1 /PROD=solute carrier family 22 (organic cationtransporter), member 1 /DB_XREF=gi:4506998 /UG=Hs.117367 solute carrier family 22 (organic cation transporter), member 1 /FL=gb:U77086.1 gb:NM_003057.1 NM_003057 solute carrier family 22 (organic cation transporter), member 1 SLC22A1 6580 NM_003057 /// NM_153187 /// XM_005267102 /// XM_005267103 /// XM_005267104 /// XM_005267105 /// XM_006715552 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // traceable author statement /// 0010248 // establishment or maintenance of transmembrane electrochemical gradient // inferred from electronic annotation /// 0015695 // organic cation transport // traceable author statement /// 0015697 // quaternary ammonium group transport // inferred from electronic annotation /// 0015844 // monoamine transport // inferred from electronic annotation /// 0015872 // dopamine transport // inferred from electronic annotation /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048241 // epinephrine transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901374 // acetate ester transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005277 // acetylcholine transmembrane transporter activity // inferred from electronic annotation /// 0005329 // dopamine transmembrane transporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from electronic annotation /// 0008513 // secondary active organic cation transmembrane transporter activity // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015101 // organic cation transmembrane transporter activity // traceable author statement /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 207202_s_at NM_003889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003889.2 /DEF=Homo sapiens nuclear receptor subfamily 1, group I, member 2 (NR1I2), transcript variant 1, mRNA. /FEA=mRNA /GEN=NR1I2 /PROD=pregnane X receptor, isoform 1 /DB_XREF=gi:11863133 /UG=Hs.118138 nuclear receptor subfamily 1, group I, member 2 /FL=gb:NM_003889.2 gb:AF061056.1 gb:AF084645.1 NM_003889 nuclear receptor subfamily 1, group I, member 2 NR1I2 8856 NM_003889 /// NM_022002 /// NM_033013 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0042908 // xenobiotic transport // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046618 // drug export // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207203_s_at AF061056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061056.1 /DEF=Homo sapiens orphan nuclear receptor PXR mRNA, complete cds. /FEA=mRNA /PROD=orphan nuclear receptor PXR /DB_XREF=gi:3511137 /UG=Hs.118138 nuclear receptor subfamily 1, group I, member 2 /FL=gb:NM_003889.2 gb:AF061056.1 gb:AF084645.1 AF061056 nuclear receptor subfamily 1, group I, member 2 NR1I2 8856 NM_003889 /// NM_022002 /// NM_033013 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0042908 // xenobiotic transport // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046618 // drug export // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207204_at NM_012418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012418.1 /DEF=Homo sapiens fascin (Strongylocentrotus purpuratus) homolog 2 (actin-bundling protein, retinal) (FSCN2), mRNA. /FEA=mRNA /GEN=FSCN2 /PROD=fascin (Strongylocentrotus purpuratus) homolog 2(actin-bundling protein, retinal) /DB_XREF=gi:6912625 /UG=Hs.118555 fascin (Strongylocentrotus purpuratus) homolog 2 (actin-bundling protein, retinal) /FL=gb:AF030165.1 gb:NM_012418.1 NM_012418 fascin actin-bundling protein 2, retinal FSCN2 25794 NM_001077182 /// NM_012418 /// XM_005257195 /// XM_005257196 0007601 // visual perception // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0008083 // growth factor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity 207205_at NM_001817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001817.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4), mRNA. /FEA=mRNA /GEN=CEACAM4 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 4 /DB_XREF=gi:4502796 /UG=Hs.12 carcinoembryonic antigen-related cell adhesion molecule 4 /FL=gb:NM_001817.1 NM_001817 carcinoembryonic antigen-related cell adhesion molecule 4 CEACAM4 1089 NM_001817 /// XM_005258434 /// XM_006722977 /// XM_006725392 /// XM_006725393 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 207206_s_at NM_000697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000697.1 /DEF=Homo sapiens arachidonate 12-lipoxygenase (ALOX12), mRNA. /FEA=mRNA /GEN=ALOX12 /PROD=arachidonate 12-lipoxygenase /DB_XREF=gi:4502050 /UG=Hs.1200 arachidonate 12-lipoxygenase /FL=gb:M62982.1 gb:M58704.1 gb:M35418.1 gb:NM_000697.1 NM_000697 arachidonate 12-lipoxygenase ALOX12 239 NM_000697 /// XM_005256588 /// XM_006721496 /// XM_006721497 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010595 // positive regulation of endothelial cell migration // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from mutant phenotype /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0019395 // fatty acid oxidation // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0042554 // superoxide anion generation // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051121 // hepoxilin metabolic process // traceable author statement /// 0051122 // hepoxilin biosynthetic process // inferred from sequence or structural similarity /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0071396 // cellular response to lipid // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // non-traceable author statement /// 0090331 // negative regulation of platelet aggregation // inferred from sequence or structural similarity /// 1901751 // leukotriene A4 metabolic process // inferred from direct assay /// 2001300 // lipoxin metabolic process // traceable author statement /// 2001303 // lipoxin A4 biosynthetic process // inferred from direct assay /// 2001306 // lipoxin B4 biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004052 // arachidonate 12-lipoxygenase activity // inferred from direct assay /// 0004052 // arachidonate 12-lipoxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016165 // linoleate 13S-lipoxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047977 // hepoxilin-epoxide hydrolase activity // inferred from sequence or structural similarity /// 0051120 // hepoxilin A3 synthase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 207207_at AF069682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF069682.2 /DEF=Homo sapiens testes specific heterogenous nuclear ribonucleoprotein G-T (hnRNPG-T) mRNA, complete cds. /FEA=mRNA /GEN=hnRNPG-T /PROD=testes specific heterogenous nuclearribonucleoprotein G-T /DB_XREF=gi:8576315 /UG=Hs.121605 testes-specific heterogenous nuclear ribonucleoprotein G-T /FL=gb:AF069682.2 gb:NM_014469.2 AF069682 RNA binding motif protein, X-linked-like 2 RBMXL2 27288 NM_014469 0005634 // nucleus // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 207208_at NM_014469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014469.2 /DEF=Homo sapiens testes-specific heterogenous nuclear ribonucleoprotein G-T (HNRNPG-T), mRNA. /FEA=mRNA /GEN=HNRNPG-T /PROD=testes-specific heterogenous nuclearribonucleoprotein G-T /DB_XREF=gi:8850216 /UG=Hs.121605 testes-specific heterogenous nuclear ribonucleoprotein G-T /FL=gb:AF069682.2 gb:NM_014469.2 NM_014469 RNA binding motif protein, X-linked-like 2 RBMXL2 27288 NM_014469 0005634 // nucleus // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 207209_at NM_004066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004066.1 /DEF=Homo sapiens centrin, EF-hand protein, 1 (CETN1), mRNA. /FEA=mRNA /GEN=CETN1 /PROD=centrin 1 /DB_XREF=gi:4757973 /UG=Hs.122511 centrin, EF-hand protein, 1 /FL=gb:U03270.1 gb:NM_004066.1 NM_004066 centrin, EF-hand protein, 1 CETN1 1068 NM_004066 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from mutant phenotype /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0032795 // heterotrimeric G-protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207210_at NM_000808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000808.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), mRNA. /FEA=mRNA /GEN=GABRA3 /PROD=gamma-aminobutyric acid A receptor, alpha 3precursor /DB_XREF=gi:4557602 /UG=Hs.123024 gamma-aminobutyric acid (GABA) A receptor, alpha 3 /FL=gb:NM_000808.1 NM_000808 gamma-aminobutyric acid (GABA) A receptor, alpha 3 GABRA3 2556 NM_000808 /// XM_005274659 /// XM_006724811 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // traceable author statement 207211_at AF079564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF079564.1 /DEF=Homo sapiens ubiquitin-specific protease UBP41 (UBP41) mRNA, complete cds. /FEA=mRNA /GEN=UBP41 /PROD=ubiquitin-specific protease UBP41 /DB_XREF=gi:3386549 /UG=Hs.125902 ubiquitin specific protease 2 /FL=gb:AF079564.1 gb:NM_004205.1 AF079564 ubiquitin specific peptidase 2 USP2 9099 NM_001243759 /// NM_004205 /// NM_171997 /// XM_005271721 /// XM_005271722 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207212_at NM_004174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004174.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 (SLC9A3), mRNA. /FEA=mRNA /GEN=SLC9A3 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 3 /DB_XREF=gi:6806920 /UG=Hs.123044 solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 /FL=gb:NM_004174.1 gb:U28043.1 NM_004174 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 SLC9A3 6550 NM_001284351 /// NM_004174 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 207213_s_at NM_004205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004205.1 /DEF=Homo sapiens ubiquitin specific protease 2 (USP2), mRNA. /FEA=mRNA /GEN=USP2 /PROD=ubiquitin specific protease 2 /DB_XREF=gi:4759291 /UG=Hs.125902 ubiquitin specific protease 2 /FL=gb:AF079564.1 gb:NM_004205.1 NM_004205 ubiquitin specific peptidase 2 USP2 9099 NM_001243759 /// NM_004205 /// NM_171997 /// XM_005271721 /// XM_005271722 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207214_at NM_014471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014471.1 /DEF=Homo sapiens gastrointestinal peptide (PEC-60), mRNA. /FEA=mRNA /GEN=PEC-60 /PROD=gastrointestinal peptide /DB_XREF=gi:7657452 /UG=Hs.129778 gastrointestinal peptide /FL=gb:AF048700.1 gb:NM_014471.1 NM_014471 serine peptidase inhibitor, Kazal type 4 SPINK4 27290 NM_014471 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207215_at NM_015371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015371.1 /DEF=Homo sapiens hypothetical protein (HS322B1A), mRNA. /FEA=mRNA /GEN=HS322B1A /PROD=hypothetical protein /DB_XREF=gi:7657185 /UG=Hs.129850 hypothetical protein /FL=gb:NM_015371.1 NM_015371 glutathione S-transferase theta pseudogene 1 GSTTP1 25774 NM_001039498 /// NM_015371 /// NR_003081 /// XR_425311 /// XR_425312 207216_at NM_001244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001244.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8), mRNA. /FEA=mRNA /GEN=TNFSF8 /PROD=tumor necrosis factor (ligand) superfamily,member 8 /DB_XREF=gi:4507606 /UG=Hs.1313 tumor necrosis factor (ligand) superfamily, member 8 /FL=gb:L09753.1 gb:NM_001244.1 NM_001244 tumor necrosis factor (ligand) superfamily, member 8 TNFSF8 944 NM_001244 /// NM_001252290 /// XM_006717325 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207217_s_at NM_013955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013955.1 /DEF=Homo sapiens NADPH oxidase 1 (NOX1), transcript variant NOH-1Lv, mRNA. /FEA=mRNA /GEN=NOX1 /PROD=NADPH oxidase 1 isoform long variant /DB_XREF=gi:7669509 /UG=Hs.132370 NADPH oxidase 1 /FL=gb:AF166328.1 gb:NM_013955.1 NM_013955 NADPH oxidase 1 NOX1 27035 NM_001271815 /// NM_007052 /// NM_013954 /// NM_013955 0001525 // angiogenesis // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred by curator /// 0006746 // FADH2 metabolic process // non-traceable author statement /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006811 // ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009268 // response to pH // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from expression pattern /// 0015992 // proton transport // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042743 // hydrogen peroxide metabolic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from direct assay /// 0072592 // oxygen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred by curator /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030171 // voltage-gated proton channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0050661 // NADP binding // inferred by curator 207218_at NM_000133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000133.2 /DEF=Homo sapiens coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) (F9), mRNA. /FEA=mRNA /GEN=F9 /PROD=coagulation factor IX /DB_XREF=gi:10518507 /UG=Hs.1330 coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) /FL=gb:NM_000133.2 gb:M11309.1 gb:J00137.1 NM_000133 coagulation factor IX F9 2158 NM_000133 /// XM_005262397 /// XM_006724742 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207219_at NM_023070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023070.1 /DEF=Homo sapiens hypothetical protein (LOC65243), mRNA. /FEA=mRNA /GEN=LOC65243 /PROD=hypothetical protein /DB_XREF=gi:12751478 /UG=Hs.133034 hypothetical protein /FL=gb:NM_023070.1 NM_023070 ZFP69 zinc finger protein B ZFP69B 65243 NM_023070 /// XM_005271136 /// XM_005271137 /// XM_005271138 /// XM_005271139 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207220_at NM_021071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021071.1 /DEF=Homo sapiens ADP-ribosyltransferase 4 (ART4), mRNA. /FEA=mRNA /GEN=ART4 /PROD=ADP-ribosyltransferase 4 /DB_XREF=gi:12711661 /UG=Hs.13776 Dombrock blood group /FL=gb:AF290204.1 gb:NM_021071.1 NM_021071 ADP-ribosyltransferase 4 (Dombrock blood group) ART4 420 NM_021071 0006471 // protein ADP-ribosylation // non-traceable author statement /// 0006525 // arginine metabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003956 // NAD(P)+-protein-arginine ADP-ribosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 207221_at NM_003950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003950.1 /DEF=Homo sapiens coagulation factor II (thrombin) receptor-like 3 (F2RL3), mRNA. /FEA=mRNA /GEN=F2RL3 /PROD=coagulation factor II (thrombin) receptor-like3 /DB_XREF=gi:4503638 /UG=Hs.137574 coagulation factor II (thrombin) receptor-like 3 /FL=gb:AF055917.1 gb:AF080214.1 gb:NM_003950.1 NM_003950 coagulation factor II (thrombin) receptor-like 3 F2RL3 9002 NM_003950 /// XM_005260139 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0060155 // platelet dense granule organization // inferred by curator /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0015057 // thrombin receptor activity // inferred from electronic annotation 207222_at NM_003561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003561.1 /DEF=Homo sapiens phospholipase A2, group X (PLA2G10), mRNA. /FEA=mRNA /GEN=PLA2G10 /PROD=phospholipase A2, group X /DB_XREF=gi:4505844 /UG=Hs.144442 phospholipase A2, group X /FL=gb:U95301.1 gb:NM_003561.1 NM_003561 uncharacterized LOC100652777 /// phospholipase A2, group X LOC100652777 /// PLA2G10 8399 /// 100652777 NM_003561 /// XM_006720958 /// XM_006720999 /// XM_006725214 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0007411 // axon guidance // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010884 // positive regulation of lipid storage // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032308 // positive regulation of prostaglandin secretion // inferred from mutant phenotype /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0051977 // lysophospholipid transport // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090370 // negative regulation of cholesterol efflux // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement 0004620 // phospholipase activity // inferred from sequence or structural similarity /// 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207223_s_at NM_005156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005156.1 /DEF=Homo sapiens regulator of differentiation (in S. pombe) 1 (ROD1), mRNA. /FEA=mRNA /GEN=ROD1 /PROD=regulator of differentiation (in S. pombe) 1 /DB_XREF=gi:4826983 /UG=Hs.145078 regulator of differentiation (in S. pombe) 1 /FL=gb:AB023967.1 gb:NM_005156.1 NM_005156 polypyrimidine tract binding protein 3 PTBP3 9991 NM_001163788 /// NM_001163790 /// NM_001244896 /// NM_001244897 /// NM_001244898 /// NM_005156 /// XM_005252324 /// XM_006717343 /// XM_006717344 /// XM_006717345 /// XM_006717346 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 207224_s_at NM_016543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016543.1 /DEF=Homo sapiens D-siglec precursor, (LOC51766), mRNA. /FEA=mRNA /GEN=LOC51766 /PROD=D-siglec precursor, /DB_XREF=gi:7706570 /UG=Hs.149250 D-siglec precursor, /FL=gb:AF178981.1 gb:NM_016543.1 NM_016543 sialic acid binding Ig-like lectin 7 SIGLEC7 27036 NM_001277201 /// NM_014385 /// NM_016543 /// NR_102350 /// XM_006723140 0007155 // cell adhesion // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // traceable author statement 207225_at NM_001088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001088.1 /DEF=Homo sapiens arylalkylamine N-acetyltransferase (AANAT), mRNA. /FEA=mRNA /GEN=AANAT /PROD=arylalkylamine N-acetyltransferase /DB_XREF=gi:4501844 /UG=Hs.152972 arylalkylamine N-acetyltransferase /FL=gb:U40347.1 gb:NM_001088.1 NM_001088 aralkylamine N-acetyltransferase AANAT 15 NM_001088 /// NM_001166579 /// NR_110548 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay /// 0007623 // circadian rhythm // inferred from mutant phenotype /// 0007623 // circadian rhythm // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0034695 // response to prostaglandin E // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004059 // aralkylamine N-acetyltransferase activity // inferred from direct assay /// 0004059 // aralkylamine N-acetyltransferase activity // non-traceable author statement /// 0004060 // arylamine N-acetyltransferase activity // inferred from electronic annotation /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 207226_at NM_003520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003520.2 /DEF=Homo sapiens H2B histone family, member D (H2BFD), mRNA. /FEA=mRNA /GEN=H2BFD /PROD=H2B histone family, member D /DB_XREF=gi:5579461 /UG=Hs.154576 H2B histone family, member D /FL=gb:NM_003520.2 NM_003520 histone cluster 1, H2bn HIST1H2BN 8341 NM_003520 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207227_x_at NM_006605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006605.1 /DEF=Homo sapiens ret finger protein-like 2 (RFPL2), mRNA. /FEA=mRNA /GEN=RFPL2 /PROD=ret finger protein-like 2 /DB_XREF=gi:5730010 /UG=Hs.157427 ret finger protein-like 2 /FL=gb:NM_006605.1 NM_006605 ret finger protein-like 2 RFPL2 10739 NM_001098527 /// NM_001159545 /// NM_001159546 /// NM_006605 /// XM_005261310 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207228_at NM_002732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002732.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, catalytic, gamma (PRKACG), mRNA. /FEA=mRNA /GEN=PRKACG /PROD=protein kinase, cAMP-dependent, catalytic,gamma /DB_XREF=gi:4506058 /UG=Hs.158029 protein kinase, cAMP-dependent, catalytic, gamma /FL=gb:M34182.1 gb:NM_002732.1 NM_002732 protein kinase, cAMP-dependent, catalytic, gamma PRKACG 5568 NM_002732 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207229_at NM_006611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006611.1 /DEF=Homo sapiens killer cell lectin-like receptor subfamily A, member 1 (KLRA1), mRNA. /FEA=mRNA /GEN=KLRA1 /PROD=killer cell lectin-like receptor subfamily A,member 1 /DB_XREF=gi:5729898 /UG=Hs.159297 killer cell lectin-like receptor subfamily A, member 1 /FL=gb:AF047445.1 gb:NM_006611.1 NM_006611 killer cell lectin-like receptor subfamily A pseudogene 1 KLRAP1 10748 NM_006611 /// NR_028045 0007166 // cell surface receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // traceable author statement 207230_at NM_016952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016952.1 /DEF=Homo sapiens surface glycoprotein, Ig superfamily member (CDO), mRNA. /FEA=mRNA /GEN=CDO /PROD=surface glycoprotein, Ig superfamily member /DB_XREF=gi:8393083 /UG=Hs.159565 surface glycoprotein, Ig superfamily member /FL=gb:AF004841.1 gb:NM_016952.1 NM_016952 cell adhesion associated, oncogene regulated CDON 50937 NM_001243597 /// NM_016952 0001708 // cell fate specification // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0014816 // satellite cell differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // traceable author statement 0005515 // protein binding // inferred from physical interaction 207231_at NM_014648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014648.1 /DEF=Homo sapiens KIAA0675 gene product (KIAA0675), mRNA. /FEA=mRNA /GEN=KIAA0675 /PROD=KIAA0675 gene product /DB_XREF=gi:7662243 /UG=Hs.165662 KIAA0675 gene product /FL=gb:AB014575.1 gb:NM_014648.1 NM_014648 DAZ interacting zinc finger protein 3 DZIP3 9666 NM_014648 /// XM_005247914 /// XM_005247915 /// XM_005247916 /// XM_005247917 /// XM_005247918 /// XM_005247919 0000209 // protein polyubiquitination // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207232_s_at NM_014648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014648.1 /DEF=Homo sapiens KIAA0675 gene product (KIAA0675), mRNA. /FEA=mRNA /GEN=KIAA0675 /PROD=KIAA0675 gene product /DB_XREF=gi:7662243 /UG=Hs.165662 KIAA0675 gene product /FL=gb:AB014575.1 gb:NM_014648.1 NM_014648 DAZ interacting zinc finger protein 3 DZIP3 9666 NM_014648 /// XM_005247914 /// XM_005247915 /// XM_005247916 /// XM_005247917 /// XM_005247918 /// XM_005247919 0000209 // protein polyubiquitination // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207233_s_at NM_000248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000248.1 /DEF=Homo sapiens microphthalmia-associated transcription factor (MITF), mRNA. /FEA=mRNA /GEN=MITF /PROD=microphthalmia-associated transcription factor /DB_XREF=gi:4557754 /UG=Hs.166017 microphthalmia-associated transcription factor /FL=gb:NM_000248.1 NM_000248 microphthalmia-associated transcription factor MITF 4286 NM_000248 /// NM_001184967 /// NM_001184968 /// NM_006722 /// NM_198158 /// NM_198159 /// NM_198177 /// NM_198178 /// XM_005264754 /// XM_005264755 /// XM_006713164 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046849 // bone remodeling // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 207234_at NM_002919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002919.1 /DEF=Homo sapiens regulatory factor X, 3 (influences HLA class II expression) (RFX3), mRNA. /FEA=mRNA /GEN=RFX3 /PROD=regulatory factor X, 3 (influences HLA class IIexpression) /DB_XREF=gi:4506494 /UG=Hs.166019 regulatory factor X, 3 (influences HLA class II expression) /FL=gb:NM_002919.1 NM_002919 regulatory factor X, 3 (influences HLA class II expression) RFX3 5991 NM_001282116 /// NM_001282117 /// NM_002919 /// NM_134428 /// XM_005251534 /// XM_006716840 /// XM_006716841 /// XM_006716842 /// XM_006716843 /// XM_006716844 /// XM_006716845 /// XM_006716846 /// XM_006716847 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0060285 // cilium-dependent cell motility // inferred from sequence or structural similarity /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from sequence or structural similarity /// 0072560 // type B pancreatic cell maturation // inferred from electronic annotation /// 2000078 // positive regulation of type B pancreatic cell development // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005667 // transcription factor complex // inferred by curator 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 207235_s_at NM_000842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000842.1 /DEF=Homo sapiens glutamate receptor, metabotropic 5 (GRM5), mRNA. /FEA=mRNA /GEN=GRM5 /PROD=glutamate receptor, metabotropic 5 /DB_XREF=gi:4504142 /UG=Hs.167185 glutamate receptor, metabotropic 5 /FL=gb:D28538.1 gb:NM_000842.1 NM_000842 glutamate receptor, metabotropic 5 GRM5 2915 NM_000842 /// NM_001143831 /// XM_006718828 /// XM_006718829 /// XM_006718830 0000185 // activation of MAPKKK activity // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // not recorded /// 0007206 // phospholipase C-activating G-protein coupled glutamate receptor signaling pathway // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0040013 // negative regulation of locomotion // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation 207236_at NM_003419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003419.1 /DEF=Homo sapiens zinc finger protein 10 (KOX 1) (ZNF10), mRNA. /FEA=mRNA /GEN=ZNF10 /PROD=zinc finger protein 10 (KOX 1) /DB_XREF=gi:4507974 /UG=Hs.169319 zinc finger protein 10 (KOX 1) /FL=gb:NM_003419.1 NM_003419 zinc finger protein 345 ZNF345 25850 NM_001242472 /// NM_001242474 /// NM_001242475 /// NM_001242476 /// NM_003419 /// NR_038362 /// XM_006723132 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207237_at NM_002232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002232.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), mRNA. /FEA=mRNA /GEN=KCNA3 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 3 /DB_XREF=gi:4504814 /UG=Hs.169948 potassium voltage-gated channel, shaker-related subfamily, member 3 /FL=gb:M85217.1 gb:L23499.1 gb:NM_002232.1 NM_002232 potassium voltage-gated channel, shaker-related subfamily, member 3 KCNA3 3738 NM_002232 /// NR_109845 /// NR_109846 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // traceable author statement /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation 207238_s_at NM_002838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002838.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), mRNA. /FEA=mRNA /GEN=PTPRC /PROD=protein tyrosine phosphatase, receptor type, C /DB_XREF=gi:4506306 /UG=Hs.170121 protein tyrosine phosphatase, receptor type, C /FL=gb:NM_002838.1 NM_002838 protein tyrosine phosphatase, receptor type, C PTPRC 5788 NM_001267798 /// NM_002838 /// NM_080921 /// NM_080922 /// NR_052021 /// XM_006711472 /// XM_006711473 /// XM_006711474 /// XM_006711475 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from mutant phenotype /// 0002378 // immunoglobulin biosynthetic process // inferred from mutant phenotype /// 0002711 // positive regulation of T cell mediated immunity // inferred from electronic annotation /// 0002923 // regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from mutant phenotype /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045577 // regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // non-traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0048539 // bone marrow development // inferred from mutant phenotype /// 0048864 // stem cell development // inferred from mutant phenotype /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050855 // regulation of B cell receptor signaling pathway // inferred from electronic annotation /// 0050857 // positive regulation of antigen receptor-mediated signaling pathway // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 2000473 // positive regulation of hematopoietic stem cell migration // inferred from mutant phenotype /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 207239_s_at NM_006201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006201.1 /DEF=Homo sapiens PCTAIRE protein kinase 1 (PCTK1), mRNA. /FEA=mRNA /GEN=PCTK1 /PROD=PCTAIRE protein kinase 1 /DB_XREF=gi:5453859 /UG=Hs.171834 PCTAIRE protein kinase 1 /FL=gb:NM_006201.1 NM_006201 cyclin-dependent kinase 16 CDK16 5127 NM_001170460 /// NM_006201 /// NM_033018 /// XM_005272614 /// XM_005272615 /// XM_006724534 /// XM_006724535 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207240_s_at NM_000233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000233.1 /DEF=Homo sapiens luteinizing hormonechoriogonadotropin receptor (LHCGR), mRNA. /FEA=mRNA /GEN=LHCGR /PROD=luteinizing hormonechoriogonadotropin receptorprecursor /DB_XREF=gi:4557716 /UG=Hs.1769 luteinizing hormonechoriogonadotropin receptor /FL=gb:M63108.1 gb:S57793.1 gb:NM_000233.1 NM_000233 luteinizing hormone/choriogonadotropin receptor LHCGR 3973 NM_000233 /// XM_005264309 /// XM_006712015 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0030539 // male genitalia development // traceable author statement /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0042700 // luteinizing hormone signaling pathway // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from sequence or structural similarity /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060065 // uterus development // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from sequence or structural similarity /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0090030 // regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004964 // luteinizing hormone receptor activity // inferred from electronic annotation /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation /// 0035472 // choriogonadotropin hormone receptor activity // inferred from sequence or structural similarity /// 0038106 // choriogonadotropin hormone binding // inferred from sequence or structural similarity 207241_at NM_005750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005750.1 /DEF=Homo sapiens chromosome 4 open reading frame 6 (C4ORF6), mRNA. /FEA=mRNA /GEN=C4ORF6 /PROD=chromosome 4 open reading frame 6 /DB_XREF=gi:5031564 /UG=Hs.177972 chromosome 4 open reading frame 6 /FL=gb:D82070.1 gb:NM_005750.1 NM_005750 chromosome 4 open reading frame 6 C4orf6 10141 NM_005750 0007399 // nervous system development // traceable author statement 207242_s_at NM_000830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000830.1 /DEF=Homo sapiens glutamate receptor, ionotropic, kainate 1 (GRIK1), mRNA. /FEA=mRNA /GEN=GRIK1 /PROD=glutamate receptor, ionotropic, kainate 1 /DB_XREF=gi:4504116 /UG=Hs.181581 glutamate receptor, ionotropic, kainate 1 /FL=gb:NM_000830.1 gb:L19058.1 NM_000830 glutamate receptor, ionotropic, kainate 1 GRIK1 2897 NM_000830 /// NM_175611 /// XM_005260942 /// XM_005260943 /// XM_005260944 /// XM_006723991 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // traceable author statement /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay 207243_s_at NM_001743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001743.1 /DEF=Homo sapiens calmodulin 2 (phosphorylase kinase, delta) (CALM2), mRNA. /FEA=mRNA /GEN=CALM2 /PROD=calmodulin 2 (phosphorylase kinase, delta) /DB_XREF=gi:4502548 /UG=Hs.182278 calmodulin 2 (phosphorylase kinase, delta) /FL=gb:M19311.1 gb:NM_001743.1 NM_001743 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 207244_x_at NM_000762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000762.2 /DEF=Homo sapiens cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 (CYP2A6), mRNA. /FEA=mRNA /GEN=CYP2A6 /PROD=cytochrome P450, subfamily IIA(phenobarbital-inducible), polypeptide 3 /DB_XREF=gi:13699805 /UG=Hs.183584 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 /FL=gb:NM_000762.2 gb:M33318.1 NM_000762 cytochrome P450, family 2, subfamily A, polypeptide 6 CYP2A6 1548 NM_000762 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207245_at NM_001077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001077.1 /DEF=Homo sapiens UDP glycosyltransferase 2 family, polypeptide B17 (UGT2B17), mRNA. /FEA=mRNA /GEN=UGT2B17 /PROD=UDP glycosyltransferase 2 family, polypeptideB17 /DB_XREF=gi:4507820 /UG=Hs.183596 UDP glycosyltransferase 2 family, polypeptide B17 /FL=gb:U59209.1 gb:NM_001077.1 NM_001077 UDP glucuronosyltransferase 2 family, polypeptide B17 UGT2B17 7367 NM_001077 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0052695 // cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 207246_at NM_003411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003411.1 /DEF=Homo sapiens zinc finger protein, Y-linked (ZFY), mRNA. /FEA=mRNA /GEN=ZFY /PROD=zinc finger protein, Y-linked /DB_XREF=gi:4507966 /UG=Hs.184915 zinc finger protein, Y-linked /FL=gb:L10393.1 gb:M30607.1 gb:NM_003411.1 NM_003411 zinc finger protein, Y-linked ZFY 7544 NM_001145275 /// NM_001145276 /// NM_003411 /// XM_005262570 /// XM_005262571 /// XM_006724873 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207247_s_at NM_003411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003411.1 /DEF=Homo sapiens zinc finger protein, Y-linked (ZFY), mRNA. /FEA=mRNA /GEN=ZFY /PROD=zinc finger protein, Y-linked /DB_XREF=gi:4507966 /UG=Hs.184915 zinc finger protein, Y-linked /FL=gb:L10393.1 gb:M30607.1 gb:NM_003411.1 NM_003411 zinc finger protein, X-linked /// zinc finger protein, Y-linked ZFX /// ZFY 7543 /// 7544 NM_001145275 /// NM_001145276 /// NM_001178084 /// NM_001178085 /// NM_001178086 /// NM_001178095 /// NM_003410 /// NM_003411 /// XM_005262570 /// XM_005262571 /// XM_005274591 /// XM_005274592 /// XM_005274594 /// XM_006724513 /// XM_006724514 /// XM_006724515 /// XM_006724873 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060746 // parental behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207248_at NM_002233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002233.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 4 (KCNA4), mRNA. /FEA=mRNA /GEN=KCNA4 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 4 /DB_XREF=gi:4504816 /UG=Hs.1854 potassium voltage-gated channel, shaker-related subfamily, member 4 /FL=gb:L02751.1 gb:M55514.1 gb:M60450.1 gb:NM_002233.1 NM_002233 potassium voltage-gated channel, shaker-related subfamily, member 4 KCNA4 3739 NM_002233 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030955 // potassium ion binding // inferred from electronic annotation 207249_s_at NM_004212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004212.1 /DEF=Homo sapiens solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (SLC28A2), mRNA. /FEA=mRNA /GEN=SLC28A2 /PROD=solute carrier family 28 (sodium-couplednucleoside transporter), member 2 /DB_XREF=gi:4759131 /UG=Hs.193665 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 /FL=gb:AF036109.1 gb:U84392.1 gb:NM_004212.1 NM_004212 solute carrier family 28 (concentrative nucleoside transporter), member 2 SLC28A2 9153 NM_004212 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015860 // purine nucleoside transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0001882 // nucleoside binding // inferred from electronic annotation /// 0005415 // nucleoside:sodium symporter activity // inferred from electronic annotation /// 0015211 // purine nucleoside transmembrane transporter activity // traceable author statement 207250_at NM_007374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007374.1 /DEF=Homo sapiens sine oculis homeobox (Drosophila) homolog 6 (SIX6), mRNA. /FEA=mRNA /GEN=SIX6 /PROD=sine oculis homeobox (Drosophila) homolog 6 /DB_XREF=gi:6677978 /UG=Hs.194756 sine oculis homeobox (Drosophila) homolog 6 /FL=gb:NM_007374.1 NM_007374 SIX homeobox 6 SIX6 4990 NM_007374 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207251_at NM_005925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005925.1 /DEF=Homo sapiens meprin A, beta (MEP1B), mRNA. /FEA=mRNA /GEN=MEP1B /PROD=meprin A, beta /DB_XREF=gi:5174550 /UG=Hs.194777 meprin A, beta /FL=gb:NM_005925.1 NM_005925 meprin A, beta MEP1B 4225 NM_005925 /// XM_005258275 0006508 // proteolysis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007586 // digestion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207252_at NM_003669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003669.1 /DEF=Homo sapiens inactivation escape 1 (INE1), mRNA. /FEA=mRNA /GEN=INE1 /PROD=inactivation escape 1 /DB_XREF=gi:4504692 /UG=Hs.199245 inactivation escape 1 /FL=gb:NM_003669.1 NM_003669 inactivation escape 1 (non-protein coding) INE1 8552 NM_003669 /// NR_024616 207253_s_at NM_016936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016936.1 /DEF=Homo sapiens ubinuclein 1 (UBN1), mRNA. /FEA=mRNA /GEN=UBN1 /PROD=ubinuclein 1 /DB_XREF=gi:9055373 /UG=Hs.21479 ubinuclein 1 /FL=gb:AF108460.1 gb:NM_016936.1 NM_016936 ubinuclein 1 UBN1 29855 NM_001079514 /// NM_001288656 /// NM_016936 /// XM_005255277 /// XM_005255278 /// XM_005255279 /// XM_005255280 /// XM_005255283 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207254_at NM_005073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005073.1 /DEF=Homo sapiens solute carrier family 15 (oligopeptide transporter), member 1 (SLC15A1), mRNA. /FEA=mRNA /GEN=SLC15A1 /PROD=solute carrier family 15 (oligopeptidetransporter), member 1 /DB_XREF=gi:4827007 /UG=Hs.2217 solute carrier family 15 (oligopeptide transporter), member 1 /FL=gb:AF043233.1 gb:NM_005073.1 gb:U21936.1 gb:U13173.1 NM_005073 solute carrier family 15 (oligopeptide transporter), member 1 SLC15A1 6564 NM_005073 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006857 // oligopeptide transport // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015833 // peptide transport // non-traceable author statement /// 0015992 // proton transport // traceable author statement /// 0035672 // oligopeptide transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005427 // proton-dependent oligopeptide secondary active transmembrane transporter activity // inferred from electronic annotation /// 0015198 // oligopeptide transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015333 // peptide:proton symporter activity // traceable author statement 207255_at NM_002303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002303.1 /DEF=Homo sapiens leptin receptor (LEPR), mRNA. /FEA=mRNA /GEN=LEPR /PROD=leptin receptor /DB_XREF=gi:4504978 /UG=Hs.226627 leptin receptor /FL=gb:U43168.1 gb:U66497.1 gb:NM_002303.1 NM_002303 leptin receptor /// leptin receptor overlapping transcript LEPR /// LEPROT 3953 /// 54741 NM_001003679 /// NM_001003680 /// NM_001198681 /// NM_001198683 /// NM_001198687 /// NM_001198688 /// NM_001198689 /// NM_002303 /// NM_017526 0006112 // energy reserve metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 207256_at NM_000242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000242.1 /DEF=Homo sapiens mannose-binding lectin (protein C) 2, soluble (opsonic defect) (MBL2), mRNA. /FEA=mRNA /GEN=MBL2 /PROD=soluble mannose-binding lectin precursor /DB_XREF=gi:4557738 /UG=Hs.2314 mannose-binding lectin (protein C) 2, soluble (opsonic defect) /FL=gb:NM_000242.1 NM_000242 mannose-binding lectin (protein C) 2, soluble MBL2 4153 NM_000242 /// XM_005269844 /// XM_006717860 /// XM_006717861 /// XM_006717862 0001867 // complement activation, lectin pathway // inferred from direct assay /// 0001867 // complement activation, lectin pathway // inferred from physical interaction /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006953 // acute-phase response // traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0006979 // response to oxidative stress // non-traceable author statement /// 0008228 // opsonization // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0051873 // killing by host of symbiont cells // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay /// 0005537 // mannose binding // non-traceable author statement /// 0005537 // mannose binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 207257_at NM_000799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000799.1 /DEF=Homo sapiens erythropoietin (EPO), mRNA. /FEA=mRNA /GEN=EPO /PROD=erythropoietin /DB_XREF=gi:4503588 /UG=Hs.2303 erythropoietin /FL=gb:NM_000799.1 NM_000799 erythropoietin EPO 2056 NM_000799 0001666 // response to hypoxia // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0042541 // hemoglobin biosynthetic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071474 // cellular hyperosmotic response // inferred from direct assay /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from direct assay /// 1902251 // negative regulation of erythrocyte apoptotic process // inferred from direct assay /// 2001258 // negative regulation of cation channel activity // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from electronic annotation 207258_at NM_005867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005867.1 /DEF=Homo sapiens Down syndrome critical region gene 4 (DSCR4), mRNA. /FEA=mRNA /GEN=DSCR4 /PROD=Down syndrome critical region protein 4 /DB_XREF=gi:5031654 /UG=Hs.23251 Down syndrome critical region gene 4 /FL=gb:AB000099.1 gb:NM_005867.1 NM_005867 Down syndrome critical region gene 4 DSCR4 10281 NM_005867 207259_at NM_017928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017928.1 /DEF=Homo sapiens hypothetical protein FLJ20694 (FLJ20694), mRNA. /FEA=mRNA /GEN=FLJ20694 /PROD=hypothetical protein FLJ20694 /DB_XREF=gi:8923622 /UG=Hs.232802 hypothetical protein FLJ20694 /FL=gb:NM_017928.1 NM_017928 long intergenic non-protein coding RNA 483 LINC00483 55018 NM_017928 /// NR_024626 /// NR_073199 207260_at NM_017521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017521.1 /DEF=Homo sapiens FEV protein (HSRNAFEV), mRNA. /FEA=mRNA /GEN=HSRNAFEV /PROD=FEV protein /DB_XREF=gi:8923788 /UG=Hs.234759 FEV protein /FL=gb:NM_017521.1 NM_017521 FEV (ETS oncogene family) FEV 54738 NM_017521 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207261_at NM_001298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001298.1 /DEF=Homo sapiens cyclic nucleotide gated channel alpha 3 (CNGA3), mRNA. /FEA=mRNA /GEN=CNGA3 /PROD=cyclic nucleotide gated channel alpha 3 /DB_XREF=gi:4502916 /UG=Hs.234785 cyclic nucleotide gated channel alpha 3 /FL=gb:AF065314.1 gb:NM_001298.1 NM_001298 cyclic nucleotide gated channel alpha 3 CNGA3 1261 NM_001079878 /// NM_001298 /// XM_006712243 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // not recorded /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0046549 // retinal cone cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 1902495 // transmembrane transporter complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005221 // intracellular cyclic nucleotide activated cation channel activity // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // inferred from mutant phenotype /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0030553 // cGMP binding // not recorded /// 0030553 // cGMP binding // inferred from mutant phenotype 207262_at NM_001638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001638.1 /DEF=Homo sapiens apolipoprotein F (APOF), mRNA. /FEA=mRNA /GEN=APOF /PROD=apolipoprotein F /DB_XREF=gi:4502164 /UG=Hs.2388 apolipoprotein F /FL=gb:L27050.1 gb:NM_001638.1 NM_001638 apolipoprotein F APOF 319 NM_001638 0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005319 // lipid transporter activity // traceable author statement /// 0015485 // cholesterol binding // traceable author statement 207263_x_at NM_017599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017599.1 /DEF=Homo sapiens transmembrane protein vezatin; hypothetical protein DKFZp761C241 (DKFZp761C241), mRNA. /FEA=mRNA /GEN=DKFZp761C241 /PROD=transmembrane protein vezatin; hypotheticalprotein DKFZp761C241 /DB_XREF=gi:8922162 /UG=Hs.24135 transmembrane protein vezatin; hypothetical protein DKFZp761C241 /FL=gb:NM_017599.1 NM_017599 vezatin, adherens junctions transmembrane protein VEZT 55591 NM_017599 /// NR_038241 /// NR_038242 /// XM_006719477 /// XM_006719478 /// XM_006719479 /// XM_006719480 /// XM_006719481 /// XM_006719482 /// XM_006719483 /// XM_006719484 /// XM_006719485 /// XM_006719486 /// XM_006719487 /// XM_006719488 /// XM_006719489 /// XM_006719490 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0043009 // chordate embryonic development // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002142 // stereocilia ankle link complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0017022 // myosin binding // inferred from electronic annotation 207264_at NM_016657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016657.1 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (KDELR3), transcript variant 2, mRNA. /FEA=mRNA /GEN=KDELR3 /PROD=KDEL receptor 3, isoform b /DB_XREF=gi:8051610 /UG=Hs.250696 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 /FL=gb:NM_016657.1 NM_016657 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 KDELR3 11015 NM_006855 /// NM_016657 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046923 // ER retention sequence binding // inferred from electronic annotation 207265_s_at NM_016657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016657.1 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (KDELR3), transcript variant 2, mRNA. /FEA=mRNA /GEN=KDELR3 /PROD=KDEL receptor 3, isoform b /DB_XREF=gi:8051610 /UG=Hs.250696 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 /FL=gb:NM_016657.1 NM_016657 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 KDELR3 11015 NM_006855 /// NM_016657 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046923 // ER retention sequence binding // inferred from electronic annotation 207266_x_at NM_016837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016837.1 /DEF=Homo sapiens RNA binding motif, single stranded interacting protein 1 (RBMS1), transcript variant MSSP-3, mRNA. /FEA=mRNA /GEN=RBMS1 /PROD=RNA binding motif, single stranded interactingprotein 1, isoform e /DB_XREF=gi:8400719 /UG=Hs.241567 RNA binding motif, single stranded interacting protein 1 /FL=gb:NM_016837.1 NM_016837 RNA binding motif, single stranded interacting protein 1 RBMS1 5937 NM_002897 /// NM_016836 /// NM_016839 /// XM_005246737 /// XM_005246738 /// XM_005246739 /// XM_005246740 /// XM_005246741 /// XM_006712671 /// XM_006712672 /// XM_006712673 /// XM_006712674 /// XM_006712675 0006260 // DNA replication // non-traceable author statement /// 0006396 // RNA processing // traceable author statement 0005634 // nucleus // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207267_s_at NM_018962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018962.1 /DEF=Homo sapiens Down syndrome critical region gene 6 (DSCR6), mRNA. /FEA=mRNA /GEN=DSCR6 /PROD=Down syndrome critical region protein 6 /DB_XREF=gi:9506556 /UG=Hs.254560 Down syndrome critical region gene 6 /FL=gb:AB037158.1 gb:NM_018962.1 NM_018962 ripply transcriptional repressor 3 RIPPLY3 53820 NM_018962 /// XM_005260993 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 207268_x_at NM_005759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005759.1 /DEF=Homo sapiens abl-interactor 12 (SH3-containing protein) (AIP-1), mRNA. /FEA=mRNA /GEN=AIP-1 /PROD=abl-interactor 12 (SH3-containing protein) /DB_XREF=gi:5031576 /UG=Hs.256315 abl-interactor 12 (SH3-containing protein) /FL=gb:NM_005759.1 gb:U23435.1 NM_005759 abl-interactor 2 ABI2 10152 NM_001282925 /// NM_001282926 /// NM_001282927 /// NM_001282932 /// NM_005759 /// XM_005246217 /// XM_005246218 /// XM_005246221 /// XM_005246222 /// XM_005246223 /// XM_005246224 /// XM_005246225 /// XM_005246226 /// XM_005246229 /// XM_006712174 /// XM_006712175 /// XM_006712176 /// XM_006712177 /// XM_006712178 /// XM_006712179 /// XM_006712180 /// XM_006712181 /// XM_006712182 /// XM_006712183 /// XM_006712184 /// XM_006712185 /// XM_006712186 0006928 // cellular component movement // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // traceable author statement /// 0019900 // kinase binding // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 207269_at NM_001925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001925.1 /DEF=Homo sapiens defensin, alpha 4, corticostatin (DEFA4), mRNA. /FEA=mRNA /GEN=DEFA4 /PROD=defensin, alpha 4, preproprotein /DB_XREF=gi:4503302 /UG=Hs.2582 defensin, alpha 4, corticostatin /FL=gb:NM_001925.1 NM_001925 defensin, alpha 4, corticostatin DEFA4 1669 NM_001925 0006952 // defense response // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement 207270_x_at NM_006678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006678.1 /DEF=Homo sapiens CMRF35 leukocyte immunoglobulin-like receptor (CMRF35), mRNA. /FEA=mRNA /GEN=CMRF35 /PROD=CMRF35 leukocyte immunoglobulin-like receptor /DB_XREF=gi:5729775 /UG=Hs.2605 CMRF35 leukocyte immunoglobulin-like receptor /FL=gb:X66171.1 gb:NM_006678.1 NM_006678 CD300c molecule CD300C 10871 NM_006678 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207271_x_at NM_016512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016512.1 /DEF=Homo sapiens sperm antigen precursor (HE2), mRNA. /FEA=mRNA /GEN=HE2 /PROD=HE2 alpha1 /DB_XREF=gi:7706550 /UG=Hs.2717 sperm associated antigen 11 /FL=gb:AF168616.1 gb:NM_016512.1 NM_016512 sperm associated antigen 11A /// sperm associated antigen 11B SPAG11A /// SPAG11B 10407 /// 653423 NM_001081552 /// NM_016512 /// NM_058200 /// NM_058201 /// NM_058202 /// NM_058203 /// NM_058206 /// NM_058207 /// XM_005272391 /// XM_005272392 /// XM_005272393 0007283 // spermatogenesis // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation 207272_at NM_007136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007136.1 /DEF=Homo sapiens zinc finger protein 80 (pT17) (ZNF80), mRNA. /FEA=mRNA /GEN=ZNF80 /PROD=zinc finger protein 80 (pT17) /DB_XREF=gi:6005981 /UG=Hs.271079 zinc finger protein 80 (pT17) /FL=gb:NM_007136.1 NM_007136 zinc finger protein 80 ZNF80 7634 NM_007136 /// XR_241507 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207273_at NM_015858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015858.1 /DEF=Homo sapiens cellular growth-regulating protein (LOC51038), mRNA. /FEA=mRNA /GEN=LOC51038 /PROD=cellular growth-regulating protein /DB_XREF=gi:7705657 /UG=Hs.274481 cellular growth-regulating protein /FL=gb:L10844.1 gb:NM_015858.1 NM_015858 207274_at NM_000080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000080.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, epsilon polypeptide (CHRNE), mRNA. /FEA=mRNA /GEN=CHRNE /PROD=nicotinic acetylcholine receptor epsilonpolypeptide precursor /DB_XREF=gi:4557462 /UG=Hs.278295 cholinergic receptor, nicotinic, epsilon polypeptide /FL=gb:NM_000080.1 NM_000080 cholinergic receptor, nicotinic, epsilon (muscle) CHRNE 1145 NM_000080 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0008324 // cation transmembrane transporter activity // traceable author statement /// 0015464 // acetylcholine receptor activity // traceable author statement 207275_s_at NM_001995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001995.1 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 1 (FACL1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FACL1 /PROD=long-chain fatty-acid-coenzyme A ligase 1 /DB_XREF=gi:4503650 /UG=Hs.278333 fatty-acid-Coenzyme A ligase, long-chain 1 /FL=gb:L09229.1 gb:NM_001995.1 NM_001995 acyl-CoA synthetase long-chain family member 1 ACSL1 2180 NM_001286708 /// NM_001286710 /// NM_001286711 /// NM_001286712 /// NM_001995 /// XM_005262827 /// XM_005262828 /// XM_005262829 /// XM_005262831 /// XM_006714138 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033211 // adiponectin-activated signaling pathway // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042178 // xenobiotic catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 207276_at NM_004065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004065.1 /DEF=Homo sapiens cerebellar degeneration-related protein (34kD) (CDR1), mRNA. /FEA=mRNA /GEN=CDR1 /PROD=cerebellar degeneration-related protein (34kD) /DB_XREF=gi:4757963 /UG=Hs.278427 cerebellar degeneration-related protein (34kD) /FL=gb:M16965.1 gb:NM_004065.1 NM_004065 cerebellar degeneration-related protein 1, 34kDa CDR1 1038 NM_004065 207277_at AF290886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF290886.1 /DEF=Homo sapiens DC-SIGN mRNA, complete cds. /FEA=mRNA /PROD=DC-SIGN /DB_XREF=gi:13383467 /UG=Hs.278694 CD209 antigen /FL=gb:NM_021155.1 gb:AF290886.1 gb:M98457.1 AF290886 CD209 molecule CD209 30835 NM_001144893 /// NM_001144894 /// NM_001144895 /// NM_001144896 /// NM_001144897 /// NM_001144899 /// NM_021155 /// NR_026692 /// XM_005272472 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0009988 // cell-cell recognition // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019062 // virion attachment to host cell // traceable author statement /// 0019079 // viral genome replication // non-traceable author statement /// 0019882 // antigen processing and presentation // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042129 // regulation of T cell proliferation // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046968 // peptide antigen transport // non-traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0030246 // carbohydrate binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046790 // virion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207278_s_at NM_021155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021155.1 /DEF=Homo sapiens CD209 antigen (CD209), mRNA. /FEA=mRNA /GEN=CD209 /PROD=CD209 antigen /DB_XREF=gi:10863956 /UG=Hs.278694 CD209 antigen /FL=gb:NM_021155.1 gb:AF290886.1 gb:M98457.1 NM_021155 CD209 molecule CD209 30835 NM_001144893 /// NM_001144894 /// NM_001144895 /// NM_001144896 /// NM_001144897 /// NM_001144899 /// NM_021155 /// NR_026692 /// XM_005272472 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0009988 // cell-cell recognition // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019062 // virion attachment to host cell // traceable author statement /// 0019079 // viral genome replication // non-traceable author statement /// 0019882 // antigen processing and presentation // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042129 // regulation of T cell proliferation // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046968 // peptide antigen transport // non-traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0030246 // carbohydrate binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046790 // virion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207279_s_at NM_016365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016365.1 /DEF=Homo sapiens nebulette (LOC51739), mRNA. /FEA=mRNA /GEN=LOC51739 /PROD=nebulette /DB_XREF=gi:7706520 /UG=Hs.278999 nebulette /FL=gb:AF047368.1 gb:NM_016365.1 NM_016365 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 207280_at NM_005162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005162.2 /DEF=Homo sapiens angiotensin receptor-like 2 (AGTRL2), mRNA. /FEA=mRNA /GEN=AGTRL2 /PROD=angiotensin receptor-like 2 /DB_XREF=gi:6031157 /UG=Hs.279535 angiotensin receptor-like 2 /FL=gb:NM_005162.2 NM_005162 RNF185 antisense RNA 1 RNF185-AS1 100852405 0006914 // autophagy // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207281_x_at NM_016378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016378.1 /DEF=Homo sapiens variable charge protein on X with two repeats (VCX-2r), mRNA. /FEA=mRNA /GEN=VCX-2r /PROD=variable charge protein on X with two repeats /DB_XREF=gi:7706758 /UG=Hs.279737 variable charge protein on X with two repeats /FL=gb:AF159127.1 gb:NM_016378.1 NM_016378 variable charge, X-linked 2 VCX2 51480 NM_016378 0006325 // chromatin organization // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0042255 // ribosome assembly // non-traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // traceable author statement 207282_s_at NM_002479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002479.1 /DEF=Homo sapiens myogenin (myogenic factor 4) (MYOG), mRNA. /FEA=mRNA /GEN=MYOG /PROD=myogenin /DB_XREF=gi:4505310 /UG=Hs.2830 myogenin (myogenic factor 4) /FL=gb:NM_002479.1 NM_002479 myogenin (myogenic factor 4) MYOG 4656 NM_002479 0001503 // ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0014737 // positive regulation of muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014873 // response to muscle activity involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0014878 // response to electrical stimulus involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0014891 // striated muscle atrophy // inferred from sequence or structural similarity /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // traceable author statement /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity /// 1901739 // regulation of myoblast fusion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0032993 // protein-DNA complex // inferred from sequence or structural similarity 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 207283_at NM_020217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020217.1 /DEF=Homo sapiens hypothetical protein DKFZp547I014 (DKFZp547I014), mRNA. /FEA=mRNA /GEN=DKFZp547I014 /PROD=hypothetical protein DKFZp547I014 /DB_XREF=gi:9910199 /UG=Hs.283611 hypothetical protein DKFZp547I014 /FL=gb:NM_020217.1 NM_020217 ribosomal protein L23a pseudogene 32 RPL23AP32 56969 NM_020217 /// NR_002229 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207284_s_at NM_020164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020164.1 /DEF=Homo sapiens junctin (LOC56921), mRNA. /FEA=mRNA /GEN=LOC56921 /PROD=junctin /DB_XREF=gi:9910363 /UG=Hs.283664 aspartate beta-hydroxylase /FL=gb:AF184241.1 gb:AF224469.1 gb:NM_020164.1 NM_020164 aspartate beta-hydroxylase ASPH 444 NM_001164750 /// NM_001164751 /// NM_001164752 /// NM_001164753 /// NM_001164754 /// NM_001164755 /// NM_001164756 /// NM_004318 /// NM_020164 /// NM_032466 /// NM_032467 /// NM_032468 /// XM_005251235 /// XM_005251236 /// XM_005251238 /// XM_005251239 /// XM_005251240 /// XM_005251241 /// XM_005251242 /// XM_005251243 /// XM_005251244 /// XM_005251246 /// XM_005251247 /// XM_005251248 /// XM_005251249 /// XM_005251250 /// XM_006716448 /// XM_006716449 0005513 // detection of calcium ion // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0018193 // peptidyl-amino acid modification // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0033198 // response to ATP // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1901879 // regulation of protein depolymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement /// 0034704 // calcium channel complex // traceable author statement 0004597 // peptide-aspartate beta-dioxygenase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 207285_x_at NM_001318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001318.2 /DEF=Homo sapiens chorionic somatomammotropin hormone-like 1 (CSHL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=CSHL1 /PROD=chorionic somatomammotropin hormone-like 1,isoform 1 /DB_XREF=gi:12545371 /UG=Hs.287269 chorionic somatomammotropin hormone-like 1 /FL=gb:NM_001318.2 NM_001318 chorionic somatomammotropin hormone-like 1 CSHL1 1444 NM_001318 /// NM_022579 /// NM_022580 /// NM_022581 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207286_at NM_025009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025009.1 /DEF=Homo sapiens hypothetical protein FLJ13621 (FLJ13621), mRNA. /FEA=mRNA /GEN=FLJ13621 /PROD=hypothetical protein FLJ13621 /DB_XREF=gi:13376528 /UG=Hs.287583 hypothetical protein FLJ13621 /FL=gb:NM_025009.1 NM_025009 centrosomal protein 135kDa CEP135 9662 NM_014645 /// NM_025009 /// XM_005265788 /// XM_006714055 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 207287_at NM_025026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025026.1 /DEF=Homo sapiens hypothetical protein FLJ14107 (FLJ14107), mRNA. /FEA=mRNA /GEN=FLJ14107 /PROD=hypothetical protein FLJ14107 /DB_XREF=gi:13376547 /UG=Hs.287624 hypothetical protein FLJ14107 /FL=gb:NM_025026.1 NM_025026 BIN3 intronic transcript 1 (non-protein coding) BIN3-IT1 80094 NM_025026 /// NR_027715 207288_at NM_025091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025091.1 /DEF=Homo sapiens hypothetical protein FLJ13330 (FLJ13330), mRNA. /FEA=mRNA /GEN=FLJ13330 /PROD=hypothetical protein FLJ13330 /DB_XREF=gi:13376649 /UG=Hs.288519 hypothetical protein FLJ13330 /FL=gb:NM_025091.1 NM_025091 ASMTL antisense RNA 1 ASMTL-AS1 80161 NM_025091 /// NR_026710 /// NR_026711 207289_at NM_004142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004142.1 /DEF=Homo sapiens matrix metalloproteinase-like 1 (MMPL1), mRNA. /FEA=mRNA /GEN=MMPL1 /PROD=matrix metalloproteinase-like 1 /DB_XREF=gi:4758727 /UG=Hs.290222 matrix metalloproteinase-like 1 /FL=gb:NM_004142.1 NM_004142 matrix metallopeptidase 25 MMP25 64386 NM_004142 /// NM_022468 /// NM_022718 0006508 // proteolysis // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0060022 // hard palate development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207290_at NM_025179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025179.1 /DEF=Homo sapiens plexin A2 (PLXNA2), mRNA. /FEA=mRNA /GEN=PLXNA2 /PROD=hypothetical protein FLJ11751 /DB_XREF=gi:13378152 /UG=Hs.300622 plexin A2 /FL=gb:NM_025179.1 NM_025179 plexin A2 PLXNA2 5362 NM_025179 /// XM_005273164 /// XM_005273165 /// XM_006711387 0001756 // somitogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0021915 // neural tube development // inferred from electronic annotation /// 0021935 // cerebellar granule cell precursor tangential migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity 207291_at NM_024081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024081.1 /DEF=Homo sapiens transmembrane gamma-carboxyglutamic acid protein 4 (TMG4), mRNA. /FEA=mRNA /GEN=TMG4 /PROD=transmembrane gamma-carboxyglutamic acid protein4 /DB_XREF=gi:13129073 /UG=Hs.306226 transmembrane gamma-carboxyglutamic acid protein 4 /FL=gb:AF326351.1 gb:NM_024081.1 NM_024081 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) PRRG4 79056 NM_024081 /// XM_005253131 /// XM_006718313 /// XM_006718314 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 207292_s_at NM_002749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002749.1 /DEF=Homo sapiens mitogen-activated protein kinase 7 (MAPK7), mRNA. /FEA=mRNA /GEN=MAPK7 /PROD=mitogen-activated protein kinase 7 /DB_XREF=gi:4506092 /UG=Hs.3080 mitogen-activated protein kinase 7 /FL=gb:NM_002749.1 gb:U25278.1 NM_002749 mitogen-activated protein kinase 7 MAPK7 5598 NM_002749 /// NM_139032 /// NM_139033 /// NM_139034 /// XM_005256719 /// XM_006721557 /// XM_006721558 /// XM_006721559 /// XM_006721560 0000165 // MAPK cascade // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030821 // negative regulation of cAMP catabolic process // non-traceable author statement /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from genetic interaction /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from electronic annotation /// 0060761 // negative regulation of response to cytokine stimulus // inferred from genetic interaction /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from genetic interaction /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction 207293_s_at U16957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16957.1 /DEF=Human angiotensin II type 2 receptor mRNA, complete cds. /FEA=mRNA /PROD=angiotensin II type 2 receptor /DB_XREF=gi:595934 /UG=Hs.3110 angiotensin receptor 2 /FL=gb:U16957.1 gb:NM_000686.2 U16957 angiotensin II receptor, type 2 AGTR2 186 NM_000686 0001822 // kidney development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // traceable author statement /// 0001991 // regulation of systemic arterial blood pressure by circulatory renin-angiotensin // inferred from sequence or structural similarity /// 0002018 // renin-angiotensin regulation of aldosterone production // inferred from electronic annotation /// 0002033 // vasodilation by angiotensin involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred by curator /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // inferred from sequence or structural similarity /// 0007263 // nitric oxide mediated signal transduction // inferred by curator /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007420 // brain development // non-traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // traceable author statement /// 0032304 // negative regulation of icosanoid secretion // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035566 // regulation of metanephros size // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0035932 // aldosterone secretion // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from physical interaction /// 0038166 // angiotensin-activated signaling pathway // traceable author statement /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // non-traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // traceable author statement 207294_at NM_000686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000686.2 /DEF=Homo sapiens angiotensin receptor 2 (AGTR2), mRNA. /FEA=mRNA /GEN=AGTR2 /PROD=angiotensin receptor 2 /DB_XREF=gi:6715584 /UG=Hs.3110 angiotensin receptor 2 /FL=gb:U16957.1 gb:NM_000686.2 NM_000686 angiotensin II receptor, type 2 AGTR2 186 NM_000686 0001822 // kidney development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // traceable author statement /// 0001991 // regulation of systemic arterial blood pressure by circulatory renin-angiotensin // inferred from sequence or structural similarity /// 0002018 // renin-angiotensin regulation of aldosterone production // inferred from electronic annotation /// 0002033 // vasodilation by angiotensin involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred by curator /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // inferred from sequence or structural similarity /// 0007263 // nitric oxide mediated signal transduction // inferred by curator /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007420 // brain development // non-traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // traceable author statement /// 0032304 // negative regulation of icosanoid secretion // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035566 // regulation of metanephros size // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0035932 // aldosterone secretion // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from physical interaction /// 0038166 // angiotensin-activated signaling pathway // traceable author statement /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // non-traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // traceable author statement 207295_at NM_001039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001039.1 /DEF=Homo sapiens sodium channel, nonvoltage-gated 1, gamma (SCNN1G), mRNA. /FEA=mRNA /GEN=SCNN1G /PROD=sodium channel, nonvoltage-gated 1, gamma /DB_XREF=gi:4506820 /UG=Hs.3112 sodium channel, nonvoltage-gated 1, gamma /FL=gb:NM_001039.1 gb:L36592.1 NM_001039 sodium channel, non-voltage-gated 1, gamma subunit SCNN1G 6340 NM_001039 /// XM_005255469 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034706 // sodium channel complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005272 // sodium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 207296_at NM_024325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024325.1 /DEF=Homo sapiens hypothetical protein MGC10715 (MGC10715), mRNA. /FEA=mRNA /GEN=MGC10715 /PROD=hypothetical protein MGC10715 /DB_XREF=gi:13236570 /UG=Hs.317169 hypothetical protein MGC10715 /FL=gb:BC002897.1 gb:NM_024325.1 NM_024325 zinc finger protein 343 ZNF343 79175 NM_001282495 /// NM_001282496 /// NM_001282497 /// NM_001282498 /// NM_001282499 /// NM_024325 /// XM_006723625 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207298_at NM_006632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006632.1 /DEF=Homo sapiens solute carrier family 17 (sodium phosphate), member 3 (SLC17A3), mRNA. /FEA=mRNA /GEN=SLC17A3 /PROD=solute carrier family 17 (sodium phosphate),member 3 /DB_XREF=gi:5730046 /UG=Hs.327179 solute carrier family 17 (sodium phosphate), member 3 /FL=gb:U90545.1 gb:NM_006632.1 NM_006632 solute carrier family 17 (organic anion transporter), member 3 SLC17A3 10786 NM_001098486 /// NM_006632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006817 // phosphate ion transport // inferred from sequence or structural similarity /// 0006855 // drug transmembrane transport // inferred from direct assay /// 0015711 // organic anion transport // inferred from direct assay /// 0015747 // urate transport // inferred from direct assay /// 0015760 // glucose-6-phosphate transport // traceable author statement /// 0015849 // organic acid transport // inferred from direct assay /// 0015893 // drug transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // inferred from sequence or structural similarity /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0044070 // regulation of anion transport // inferred from direct assay /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005436 // sodium:phosphate symporter activity // inferred from sequence or structural similarity /// 0008308 // voltage-gated anion channel activity // inferred from direct assay /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015143 // urate transmembrane transporter activity // inferred from direct assay /// 0015238 // drug transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0019534 // toxin transporter activity // inferred from direct assay 207299_s_at NM_000838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000838.2 /DEF=Homo sapiens glutamate receptor, metabotropic 1 (GRM1), mRNA. /FEA=mRNA /GEN=GRM1 /PROD=glutamate receptor, metabotropic 1 /DB_XREF=gi:6006005 /UG=Hs.32945 glutamate receptor, metabotropic 1 /FL=gb:L76627.1 gb:NM_000838.2 gb:U31215.1 NM_000838 glutamate receptor, metabotropic 1 GRM1 2911 NM_000838 /// NM_001114329 /// NM_001278064 /// NM_001278065 /// NM_001278066 /// NM_001278067 /// XM_006715467 /// XM_006715468 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // not recorded /// 0007216 // G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0038042 // dimeric G-protein coupled receptor signaling pathway // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from mutant phenotype /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from direct assay /// 0038038 // G-protein coupled receptor homodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0008066 // glutamate receptor activity // traceable author statement 207300_s_at NM_000131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000131.2 /DEF=Homo sapiens coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant 1, mRNA. /FEA=mRNA /GEN=F7 /PROD=coagulation factor VII precursor, isoform a /DB_XREF=gi:10518501 /UG=Hs.36989 coagulation factor VII (serum prothrombin conversion accelerator) /FL=gb:NM_000131.2 gb:M13232.1 NM_000131 coagulation factor VII (serum prothrombin conversion accelerator) F7 2155 NM_000131 /// NM_001267554 /// NM_019616 /// NR_051961 /// XM_006719963 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010641 // positive regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032571 // response to vitamin K // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060416 // response to growth hormone // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207301_at NM_001962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001962.1 /DEF=Homo sapiens ephrin-A5 (EFNA5), mRNA. /FEA=mRNA /GEN=EFNA5 /PROD=ephrin-A5 /DB_XREF=gi:4503486 /UG=Hs.37142 ephrin-A5 /FL=gb:U26403.1 gb:NM_001962.1 NM_001962 ephrin-A5 EFNA5 1946 NM_001962 /// XM_006714565 0006915 // apoptotic process // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 207302_at NM_000231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000231.1 /DEF=Homo sapiens sarcoglycan, gamma (35kD dystrophin-associated glycoprotein) (SGCG), mRNA. /FEA=mRNA /GEN=SGCG /PROD=gamma sarcoglycan /DB_XREF=gi:4557846 /UG=Hs.37167 sarcoglycan, gamma (35kD dystrophin-associated glycoprotein) /FL=gb:U34976.1 gb:NM_000231.1 NM_000231 sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) SGCG 6445 NM_000231 /// XM_005266505 /// XM_006719861 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207303_at NM_005020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005020.1 /DEF=Homo sapiens phosphodiesterase 1C, calmodulin-dependent (70kD) (PDE1C), mRNA. /FEA=mRNA /GEN=PDE1C /PROD=phosphodiesterase 1C, calmodulin-dependent(70kD) /DB_XREF=gi:4826893 /UG=Hs.41718 phosphodiesterase 1C, calmodulin-dependent (70kD) /FL=gb:U40371.1 gb:NM_005020.1 NM_005020 phosphodiesterase 1C, calmodulin-dependent 70kDa PDE1C 5137 NM_001191056 /// NM_001191057 /// NM_001191058 /// NM_001191059 /// NM_005020 /// XM_005249768 /// XM_005249769 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004117 // calmodulin-dependent cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207304_at NM_003425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003425.1 /DEF=Homo sapiens zinc finger protein 45 (a Kruppel-associated box (KRAB) domain polypeptide) (ZNF45), mRNA. /FEA=mRNA /GEN=ZNF45 /PROD=zinc finger protein 45 (a Kruppel-associated box(KRAB) domain polypeptide) /DB_XREF=gi:4508028 /UG=Hs.41728 zinc finger protein 45 (a Kruppel-associated box (KRAB) domain polypeptide) /FL=gb:L75847.1 gb:NM_003425.1 NM_003425 zinc finger protein 45 ZNF45 7596 NM_003425 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207305_s_at NM_014939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014939.1 /DEF=Homo sapiens KIAA1012 protein (KIAA1012), mRNA. /FEA=mRNA /GEN=KIAA1012 /PROD=KIAA1012 protein /DB_XREF=gi:7662447 /UG=Hs.42959 KIAA1012 protein /FL=gb:AB023229.1 gb:NM_014939.1 NM_014939 trafficking protein particle complex 8 TRAPPC8 22878 NM_014939 /// XM_005258233 /// XM_005258234 /// XM_005258235 /// XM_006722420 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 207306_at NM_004609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004609.1 /DEF=Homo sapiens transcription factor 15 (basic helix-loop-helix) (TCF15), mRNA. /FEA=mRNA /GEN=TCF15 /PROD=transcription factor 15 (basichelix-loop-helix) /DB_XREF=gi:4759217 /UG=Hs.437 transcription factor 15 (basic helix-loop-helix) /FL=gb:NM_004609.1 gb:U08336.1 NM_004609 transcription factor 15 (basic helix-loop-helix) TCF15 6939 NM_004609 0001756 // somitogenesis // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043583 // ear development // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 207307_at NM_000868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000868.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), mRNA. /FEA=mRNA /GEN=HTR2C /PROD=5-hydroxytryptamine (serotonin) receptor 2C /DB_XREF=gi:4504540 /UG=Hs.46362 5-hydroxytryptamine (serotonin) receptor 2C /FL=gb:U49516.1 gb:NM_000868.1 gb:AF208053.1 NM_000868 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled HTR2C 3358 NM_000868 /// NM_001256760 /// NM_001256761 0001662 // behavioral fear response // inferred from sequence or structural similarity /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007208 // phospholipase C-activating serotonin receptor signaling pathway // inferred from sequence or structural similarity /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from sequence or structural similarity /// 0009451 // RNA modification // inferred from electronic annotation /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0031644 // regulation of neurological system process // inferred from sequence or structural similarity /// 0032098 // regulation of appetite // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from direct assay /// 0043397 // regulation of corticotropin-releasing hormone secretion // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001587 // Gq/11-coupled serotonin receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0051378 // serotonin binding // inferred from direct assay /// 0071886 // 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding // inferred from direct assay 207308_at NM_021094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021094.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 3 (SLC21A3), mRNA. /FEA=mRNA /GEN=SLC21A3 /PROD=organic anion transporting polypeptide A /DB_XREF=gi:10835098 /UG=Hs.46440 solute carrier family 21 (organic anion transporter), member 3 /FL=gb:NM_021094.1 gb:AF279784.1 gb:NM_005075.1 gb:U21943.1 NM_021094 solute carrier organic anion transporter family, member 1A2 SLCO1A2 6579 NM_005075 /// NM_021094 /// NM_134431 /// XM_005253474 /// XM_005253477 /// XM_005253478 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement 207309_at NM_000620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000620.1 /DEF=Homo sapiens nitric oxide synthase 1 (neuronal) (NOS1), mRNA. /FEA=mRNA /GEN=NOS1 /PROD=nitric oxide synthase 1 (neuronal) /DB_XREF=gi:10835172 /UG=Hs.46752 nitric oxide synthase 1 (neuronal) /FL=gb:NM_000620.1 gb:L02881.1 gb:D16408.1 gb:U17327.1 gb:U31466.1 NM_000620 nitric oxide synthase 1 (neuronal) NOS1 4842 NM_000620 /// NM_001204213 /// NM_001204214 /// NM_001204218 /// XM_006719426 /// XM_006719427 /// XM_006719428 /// XR_429103 0001666 // response to hypoxia // inferred from expression pattern /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0006527 // arginine catabolic process // inferred by curator /// 0006809 // nitric oxide biosynthetic process // not recorded /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // not recorded /// 0007520 // myoblast fusion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009408 // response to heat // inferred from direct assay /// 0010523 // negative regulation of calcium ion transport into cytosol // traceable author statement /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 0031284 // positive regulation of guanylate cyclase activity // not recorded /// 0033555 // multicellular organismal response to stress // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051612 // negative regulation of serotonin uptake // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 1902307 // positive regulation of sodium ion transmembrane transport // inferred from sequence or structural similarity 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0004517 // nitric-oxide synthase activity // not recorded /// 0004517 // nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // not recorded /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0034617 // tetrahydrobiopterin binding // non-traceable author statement /// 0034618 // arginine binding // traceable author statement /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0050661 // NADP binding // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 207310_s_at U31466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31466.1 /DEF=Human retinal nitric oxide synthase (NOS) mRNA, complete cds. /FEA=mRNA /GEN=NOS /PROD=nitric oxide synthase /DB_XREF=gi:951318 /UG=Hs.46752 nitric oxide synthase 1 (neuronal) /FL=gb:NM_000620.1 gb:L02881.1 gb:D16408.1 gb:U17327.1 gb:U31466.1 U31466 nitric oxide synthase 1 (neuronal) NOS1 4842 NM_000620 /// NM_001204213 /// NM_001204214 /// NM_001204218 /// XM_006719426 /// XM_006719427 /// XM_006719428 /// XR_429103 0001666 // response to hypoxia // inferred from expression pattern /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0006527 // arginine catabolic process // inferred by curator /// 0006809 // nitric oxide biosynthetic process // not recorded /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // not recorded /// 0007520 // myoblast fusion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009408 // response to heat // inferred from direct assay /// 0010523 // negative regulation of calcium ion transport into cytosol // traceable author statement /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 0031284 // positive regulation of guanylate cyclase activity // not recorded /// 0033555 // multicellular organismal response to stress // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051612 // negative regulation of serotonin uptake // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 1902307 // positive regulation of sodium ion transmembrane transport // inferred from sequence or structural similarity 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0004517 // nitric-oxide synthase activity // not recorded /// 0004517 // nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // not recorded /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0034617 // tetrahydrobiopterin binding // non-traceable author statement /// 0034618 // arginine binding // traceable author statement /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0050661 // NADP binding // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 207311_at NM_003585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003585.1 /DEF=Homo sapiens double C2-like domains, beta (DOC2B), mRNA. /FEA=mRNA /GEN=DOC2B /PROD=double C2-like domains, beta /DB_XREF=gi:6005996 /UG=Hs.54402 double C2-like domains, beta /FL=gb:D70830.1 gb:NM_003585.1 NM_003585 double C2-like domains, beta DOC2B 8447 NM_003585 /// XM_006721361 /// XM_006721362 0006810 // transport // inferred from electronic annotation /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0031340 // positive regulation of vesicle fusion // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0019905 // syntaxin binding // inferred from electronic annotation 207312_at NM_006213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006213.1 /DEF=Homo sapiens phosphorylase kinase, gamma 1 (muscle) (PHKG1), mRNA. /FEA=mRNA /GEN=PHKG1 /PROD=phosphorylase kinase, gamma 1 (muscle) /DB_XREF=gi:5453881 /UG=Hs.54929 phosphorylase kinase, gamma 1 (muscle) /FL=gb:NM_006213.1 NM_006213 phosphorylase kinase, gamma 1 (muscle) PHKG1 5260 NM_001258459 /// NM_001258460 /// NM_006213 /// NR_047689 /// XM_005271772 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation 207313_x_at L76666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76666.1 /DEF=Homo sapiens NKAT4b mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:1217718 /UG=Hs.56328 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 /FL=gb:U30272.1 gb:L76665.1 gb:L76666.1 gb:NM_006737.1 gb:L41270.1 L76666 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 KIR3DL1 /// KIR3DL2 3811 /// 3812 NM_001242867 /// NM_006737 /// NM_013289 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 207314_x_at NM_006737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006737.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 (KIR3DL2), mRNA. /FEA=mRNA /GEN=KIR3DL2 /PROD=killer cell immunoglobulin-like receptor, threedomains, long cytoplasmic tail, 2 /DB_XREF=gi:5803051 /UG=Hs.56328 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 /FL=gb:U30272.1 gb:L76665.1 gb:L76666.1 gb:NM_006737.1 gb:L41270.1 NM_006737 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 KIR3DL1 /// KIR3DL2 3811 /// 3812 NM_001242867 /// NM_006737 /// NM_013289 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 207315_at NM_006566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006566.1 /DEF=Homo sapiens adhesion glycoprotein (DNAM-1), mRNA. /FEA=mRNA /GEN=DNAM-1 /PROD=adhesion glycoprotein /DB_XREF=gi:5729807 /UG=Hs.57699 adhesion glycoprotein /FL=gb:U56102.1 gb:NM_006566.1 NM_006566 CD226 molecule CD226 10666 NM_006566 /// XM_005266642 /// XM_005266643 /// XM_006722373 /// XM_006722374 0001816 // cytokine production // inferred from electronic annotation /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0002891 // positive regulation of immunoglobulin mediated immune response // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0033005 // positive regulation of mast cell activation // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 207316_at NM_001523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001523.1 /DEF=Homo sapiens hyaluronan synthase 1 (HAS1), mRNA. /FEA=mRNA /GEN=HAS1 /PROD=hyaluronan synthase 1 /DB_XREF=gi:4504338 /UG=Hs.57697 hyaluronan synthase 1 /FL=gb:D84424.1 gb:U59269.1 gb:NM_001523.1 NM_001523 hyaluronan synthase 1 HAS1 3036 NM_001297436 /// NM_001523 /// XM_005258834 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0010764 // negative regulation of fibroblast migration // inferred from mutant phenotype /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030213 // hyaluronan biosynthetic process // inferred from electronic annotation /// 0030213 // hyaluronan biosynthetic process // traceable author statement /// 0036120 // cellular response to platelet-derived growth factor stimulus // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from sequence or structural similarity /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0050501 // hyaluronan synthase activity // inferred from sequence or structural similarity 207317_s_at NM_001232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001232.1 /DEF=Homo sapiens calsequestrin 2 (cardiac muscle) (CASQ2), mRNA. /FEA=mRNA /GEN=CASQ2 /PROD=cardiac calsequestrin 2 /DB_XREF=gi:4557408 /UG=Hs.57975 calsequestrin 2 (cardiac muscle) /FL=gb:D55655.1 gb:NM_001232.1 NM_001232 calsequestrin 2 (cardiac muscle) CASQ2 845 NM_001232 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0005513 // detection of calcium ion // traceable author statement /// 0006941 // striated muscle contraction // traceable author statement /// 0010649 // regulation of cell communication by electrical coupling // inferred from mutant phenotype /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from sequence or structural similarity /// 0051208 // sequestering of calcium ion // inferred from direct assay /// 0051208 // sequestering of calcium ion // inferred from mutant phenotype /// 0051258 // protein polymerization // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0071313 // cellular response to caffeine // inferred from mutant phenotype /// 0086029 // Purkinje myocyte to ventricular cardiac muscle cell signaling // non-traceable author statement /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // inferred by curator /// 0034704 // calcium channel complex // traceable author statement 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 207318_s_at AJ297710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ297710.1 /DEF=Homo sapiens mRNA for CDC2L5 protein kinase, (CDC2L5 gene), isoform 2. /FEA=mRNA /GEN=CDC2L5 /PROD=CDC2L5 protein kinase /DB_XREF=gi:10443223 /UG=Hs.59498 cell division cycle 2-like 5 (cholinesterase-related cell division controller) /FL=gb:M80629.1 gb:NM_003718.1 AJ297710 cyclin-dependent kinase 13 CDK13 8621 NM_003718 /// NM_031267 0000380 // alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0000380 // alternative mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207319_s_at NM_003718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003718.1 /DEF=Homo sapiens cell division cycle 2-like 5 (cholinesterase-related cell division controller) (CDC2L5), mRNA. /FEA=mRNA /GEN=CDC2L5 /PROD=cell division cycle 2-like 5(cholinesterase-related cell division controller) /DB_XREF=gi:4502710 /UG=Hs.59498 cell division cycle 2-like 5 (cholinesterase-related cell division controller) /FL=gb:M80629.1 gb:NM_003718.1 NM_003718 cyclin-dependent kinase 13 CDK13 8621 NM_003718 /// NM_031267 0000380 // alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0000380 // alternative mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207320_x_at NM_004602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004602.1 /DEF=Homo sapiens staufen (Drosophila, RNA-binding protein) (STAU), transcript variant T4, mRNA. /FEA=mRNA /GEN=STAU /PROD=staufen, isoform a /DB_XREF=gi:4759175 /UG=Hs.6113 staufen (Drosophila, RNA-binding protein) /FL=gb:AF061941.1 gb:NM_004602.1 NM_004602 staufen double-stranded RNA binding protein 1 STAU1 6780 NM_001037328 /// NM_004602 /// NM_017452 /// NM_017453 /// NM_017454 /// XM_005260524 /// XM_005260525 /// XM_005260526 /// XM_005260527 /// XM_005260528 /// XM_005260529 /// XM_006723865 /// XM_006723866 /// XM_006723867 /// XM_006723868 /// XM_006723869 0008298 // intracellular mRNA localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207321_s_at NM_019625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019625.1 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 9 (ABCB9), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCB9 /PROD=ATP-binding cassette, sub-family B, member 9,isoform 1 /DB_XREF=gi:9955965 /UG=Hs.6129 ATP-binding cassette, sub-family B (MDRTAP), member 9 /FL=gb:AB045381.2 gb:AF216494.1 gb:NM_019625.1 NM_019625 ATP-binding cassette, sub-family B (MDR/TAP), member 9 ABCB9 23457 NM_001243013 /// NM_001243014 /// NM_019624 /// NM_019625 /// NM_203444 /// NM_203445 /// XM_005253558 /// XM_005253559 /// XM_006719314 /// XR_429086 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from direct assay /// 0055085 // transmembrane transport // not recorded 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015421 // oligopeptide-transporting ATPase activity // /// 0015440 // peptide-transporting ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from direct assay /// 0042288 // MHC class I protein binding // /// 0042605 // peptide antigen binding // /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046978 // TAP1 binding // /// 0046979 // TAP2 binding // /// 0046980 // tapasin binding // 207322_at NM_003024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003024.1 /DEF=Homo sapiens intersectin 1 (SH3 domain protein) (ITSN1), mRNA. /FEA=mRNA /GEN=ITSN1 /PROD=intersectin 1 (SH3 domain protein) /DB_XREF=gi:4504796 /UG=Hs.66392 intersectin 1 (SH3 domain protein) /FL=gb:AF064244.1 gb:NM_003024.1 gb:AF114487.1 NM_003024 intersectin 1 (SH3 domain protein) ITSN1 6453 NM_001001132 /// NM_003024 /// XM_005261026 /// XM_005261027 /// XM_005261031 /// XR_244289 0006897 // endocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 207323_s_at NM_002385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002385.1 /DEF=Homo sapiens myelin basic protein (MBP), mRNA. /FEA=mRNA /GEN=MBP /PROD=myelin basic protein /DB_XREF=gi:4505122 /UG=Hs.69547 myelin basic protein /FL=gb:M30516.1 gb:NM_002385.1 NM_002385 myelin basic protein MBP 4155 NM_001025081 /// NM_001025090 /// NM_001025092 /// NM_001025094 /// NM_001025098 /// NM_001025100 /// NM_001025101 /// NM_002385 /// XM_005266699 /// XR_245459 /// XR_245460 /// XR_245461 /// XR_430073 /// XR_430074 0006955 // immune response // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008366 // axon ensheathment // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042552 // myelination // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0061024 // membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033269 // internode region of axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 207324_s_at NM_004948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004948.2 /DEF=Homo sapiens desmocollin 1 (DSC1), transcript variant Dsc1b, mRNA. /FEA=mRNA /GEN=DSC1 /PROD=desmocollin 1, isoform Dsc1b preproprotein /DB_XREF=gi:13435362 /UG=Hs.69752 desmocollin 1 /FL=gb:NM_004948.2 NM_004948 desmocollin 1 DSC1 1823 NM_004948 /// NM_024421 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207325_x_at NM_004988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004988.1 /DEF=Homo sapiens melanoma antigen, family A, 1 (directs expression of antigen MZ2-E) (MAGEA1), mRNA. /FEA=mRNA /GEN=MAGEA1 /PROD=melanoma antigen, family A, 1 (directsexpression of antigen MZ2-E) /DB_XREF=gi:4826821 /UG=Hs.72879 melanoma antigen, family A, 1 (directs expression of antigen MZ2-E) /FL=gb:NM_004988.1 NM_004988 melanoma antigen family A, 1 (directs expression of antigen MZ2-E) MAGEA1 4100 NM_004988 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from direct assay 207326_at NM_001729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001729.1 /DEF=Homo sapiens betacellulin (BTC), mRNA. /FEA=mRNA /GEN=BTC /PROD=betacellulin /DB_XREF=gi:4502460 /UG=Hs.73105 betacellulin /FL=gb:NM_001729.1 NM_001729 betacellulin BTC 685 NM_001729 /// XM_005263190 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 207327_at NM_004100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004100.1 /DEF=Homo sapiens eyes absent (Drosophila) homolog 4 (EYA4), mRNA. /FEA=mRNA /GEN=EYA4 /PROD=eyes absent (Drosophila) homolog 4 /DB_XREF=gi:4758319 /UG=Hs.73393 eyes absent (Drosophila) homolog 4 /FL=gb:Y17114.1 gb:NM_004100.1 NM_004100 EYA transcriptional coactivator and phosphatase 4 EYA4 2070 NM_004100 /// NM_172103 /// NM_172104 /// NM_172105 /// XM_005266850 /// XM_005266851 /// XM_005266852 /// XM_005266853 /// XM_006715373 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207328_at NM_001140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001140.1 /DEF=Homo sapiens arachidonate 15-lipoxygenase (ALOX15), mRNA. /FEA=mRNA /GEN=ALOX15 /PROD=arachidonate 15-lipoxygenase /DB_XREF=gi:4502054 /UG=Hs.73809 arachidonate 15-lipoxygenase /FL=gb:M23892.1 gb:NM_001140.1 NM_001140 arachidonate 15-lipoxygenase ALOX15 246 NM_001140 0001503 // ossification // inferred from sequence or structural similarity /// 0002820 // negative regulation of adaptive immune response // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from sequence or structural similarity /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0035358 // regulation of peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0035963 // cellular response to interleukin-13 // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0051122 // hepoxilin biosynthetic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 1901074 // regulation of engulfment of apoptotic cell // inferred from sequence or structural similarity /// 2001303 // lipoxin A4 biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay 0004052 // arachidonate 12-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050473 // arachidonate 15-lipoxygenase activity // inferred from direct assay /// 0050473 // arachidonate 15-lipoxygenase activity // non-traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0097260 // eoxin A4 synthase activity // traceable author statement 207329_at NM_002424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002424.1 /DEF=Homo sapiens matrix metalloproteinase 8 (neutrophil collagenase) (MMP8), mRNA. /FEA=mRNA /GEN=MMP8 /PROD=matrix metalloproteinase 8 preproprotein /DB_XREF=gi:4505220 /UG=Hs.73862 matrix metalloproteinase 8 (neutrophil collagenase) /FL=gb:J05556.1 gb:NM_002424.1 NM_002424 matrix metallopeptidase 8 (neutrophil collagenase) MMP8 4317 NM_002424 /// XM_006718841 0006508 // proteolysis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207330_at NM_002864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002864.1 /DEF=Homo sapiens pregnancy-zone protein (PZP), mRNA. /FEA=mRNA /GEN=PZP /PROD=pregnancy-zone protein /DB_XREF=gi:4506354 /UG=Hs.74094 pregnancy-zone protein /FL=gb:NM_002864.1 NM_002864 pregnancy-zone protein PZP 5858 NM_002864 0007565 // female pregnancy // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207331_at NM_016343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016343.1 /DEF=Homo sapiens centromere protein F (350400kD, mitosin) (CENPF), mRNA. /FEA=mRNA /GEN=CENPF /PROD=centromere protein F (350400kD, mitosin) /DB_XREF=gi:7706650 /UG=Hs.77204 centromere protein F (350400kD, mitosin) /FL=gb:AF118076.1 gb:NM_016343.1 NM_016343 centromere protein F, 350/400kDa CENPF 1063 NM_016343 0000085 // mitotic G2 phase // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from direct assay /// 0000087 // mitotic M phase // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007059 // chromosome segregation // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0015031 // protein transport // inferred from direct assay /// 0015031 // protein transport // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051310 // metaphase plate congression // inferred from direct assay /// 0051382 // kinetochore assembly // non-traceable author statement /// 0051726 // regulation of cell cycle // traceable author statement 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000785 // chromatin // non-traceable author statement /// 0000922 // spindle pole // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0045502 // dynein binding // inferred from direct assay 207332_s_at NM_003234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003234.1 /DEF=Homo sapiens transferrin receptor (p90, CD71) (TFRC), mRNA. /FEA=mRNA /GEN=TFRC /PROD=transferrin receptor (p90, CD71) /DB_XREF=gi:4507456 /UG=Hs.77356 transferrin receptor (p90, CD71) /FL=gb:NM_003234.1 NM_003234 transferrin receptor TFRC 7037 NM_001128148 /// NM_003234 0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0097286 // iron ion import // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004998 // transferrin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207333_at NM_002511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002511.1 /DEF=Homo sapiens neuromedin B receptor (NMBR), mRNA. /FEA=mRNA /GEN=NMBR /PROD=neuromedin B receptor /DB_XREF=gi:4505406 /UG=Hs.79042 neuromedin B receptor /FL=gb:M73482.1 gb:NM_002511.1 NM_002511 neuromedin B receptor NMBR 4829 NM_002511 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0031989 // bombesin receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004946 // bombesin receptor activity // inferred from electronic annotation 207334_s_at NM_003242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003242.1 /DEF=Homo sapiens transforming growth factor, beta receptor II (70-80kD) (TGFBR2), mRNA. /FEA=mRNA /GEN=TGFBR2 /PROD=transforming growth factor, beta receptor II(70-80kD) /DB_XREF=gi:4507468 /UG=Hs.82028 transforming growth factor, beta receptor II (70-80kD) /FL=gb:M85079.1 gb:NM_003242.1 NM_003242 transforming growth factor, beta receptor II (70/80kDa) TGFBR2 7048 NM_001024847 /// NM_003242 /// XM_006713316 0001568 // blood vessel development // traceable author statement /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002651 // positive regulation of tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002663 // positive regulation of B cell tolerance induction // inferred from sequence or structural similarity /// 0002666 // positive regulation of T cell tolerance induction // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred by curator /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032924 // activin receptor signaling pathway // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0043415 // positive regulation of skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060433 // bronchus development // inferred from electronic annotation /// 0060434 // bronchus morphogenesis // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060440 // trachea formation // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred by curator /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from mutant phenotype /// 0005026 // transforming growth factor beta receptor activity, type II // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034714 // type III transforming growth factor beta receptor binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 207335_x_at NM_007100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007100.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e (ATP5I), mRNA. /FEA=mRNA /GEN=ATP5I /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit e /DB_XREF=gi:6005716 /UG=Hs.85539 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e /FL=gb:D50371.1 gb:NM_007100.1 NM_007100 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E ATP5I 521 NM_007100 /// NR_033743 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 207336_at NM_006940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006940.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 5 (SOX5), mRNA. /FEA=mRNA /GEN=SOX5 /PROD=SRY (sex determining region Y)-box 5 /DB_XREF=gi:5902113 /UG=Hs.87224 SRY (sex determining region Y)-box 5 /FL=gb:NM_006940.1 NM_006940 SRY (sex determining region Y)-box 5 SOX5 6660 NM_001261414 /// NM_001261415 /// NM_006940 /// NM_152989 /// NM_178010 /// XM_006719149 /// XM_006719150 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207337_at NM_020994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020994.1 /DEF=Homo sapiens cancertestis antigen 2 (CTAG2), mRNA. /FEA=mRNA /GEN=CTAG2 /PROD=cancertestis antigen 2 /DB_XREF=gi:10337608 /UG=Hs.87225 cancertestis antigen 2 /FL=gb:NM_020994.1 gb:BC002833.1 NM_020994 cancer/testis antigen 2 CTAG2 30848 NM_020994 /// NM_172377 0005813 // centrosome // inferred from direct assay 207338_s_at NM_003454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003454.1 /DEF=Homo sapiens zinc finger protein 200 (ZNF200), mRNA. /FEA=mRNA /GEN=ZNF200 /PROD=zinc finger protein 200 /DB_XREF=gi:4508012 /UG=Hs.88219 zinc finger protein 200 /FL=gb:AF060866.1 gb:NM_003454.1 NM_003454 zinc finger protein 200 ZNF200 7752 NM_001145446 /// NM_001145447 /// NM_001145448 /// NM_003454 /// NM_198087 /// NM_198088 /// XM_005255556 /// XM_006720940 /// XM_006720941 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207339_s_at NM_002341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002341.1 /DEF=Homo sapiens lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1, mRNA. /FEA=mRNA /GEN=LTB /PROD=lymphotoxin-beta isoform a /DB_XREF=gi:4505034 /UG=Hs.890 lymphotoxin beta (TNF superfamily, member 3) /FL=gb:L11015.1 gb:NM_002341.1 NM_002341 lymphotoxin beta (TNF superfamily, member 3) LTB 4050 NM_002341 /// NM_009588 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from sequence or structural similarity /// 0048535 // lymph node development // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207341_at NM_002777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002777.2 /DEF=Homo sapiens proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen) (PRTN3), mRNA. /FEA=mRNA /GEN=PRTN3 /PROD=proteinase 3 (serine proteinase, neutrophil,Wegener granulomatosis autoantigen) /DB_XREF=gi:7382457 /UG=Hs.928 proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen) /FL=gb:M75154.1 gb:M29142.1 gb:NM_002777.2 NM_002777 proteinase 3 PRTN3 5657 NM_002777 0006508 // proteolysis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 207342_at NM_001297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001297.1 /DEF=Homo sapiens cyclic nucleotide gated channel beta 1 (CNGB1), mRNA. /FEA=mRNA /GEN=CNGB1 /PROD=cyclic nucleotide gated channel beta 1 /DB_XREF=gi:4502918 /UG=Hs.93909 cyclic nucleotide gated channel beta 1 /FL=gb:AF042498.1 gb:NM_001297.1 NM_001297 cyclic nucleotide gated channel beta 1 CNGB1 1258 NM_001135639 /// NM_001286130 /// NM_001297 /// XM_006721134 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017071 // intracellular cyclic nucleotide activated cation channel complex // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 1902495 // transmembrane transporter complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from electronic annotation /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0030552 // cAMP binding // inferred from electronic annotation /// 0030553 // cGMP binding // not recorded /// 0030553 // cGMP binding // inferred from direct assay /// 0043855 // cyclic nucleotide-gated ion channel activity // inferred from electronic annotation 207343_at NM_020426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020426.1 /DEF=Homo sapiens lysozyme homolog (LOC57151), mRNA. /FEA=mRNA /GEN=LOC57151 /PROD=lysozyme homolog /DB_XREF=gi:9966904 /UG=Hs.97477 lysozyme homolog /FL=gb:NM_020426.1 NM_020426 lysozyme-like 6 LYZL6 57151 NM_001199951 /// NM_020426 /// XM_005258013 /// XM_006725329 0008152 // metabolic process // inferred from electronic annotation /// 0016998 // cell wall macromolecule catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003796 // lysozyme activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 207344_at NM_006422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006422.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 3 (AKAP3), mRNA. /FEA=mRNA /GEN=AKAP3 /PROD=A kinase (PRKA) anchor protein 3 /DB_XREF=gi:5454075 /UG=Hs.98397 A kinase (PRKA) anchor protein 3 /FL=gb:AF087003.1 gb:AF093408.1 gb:U85715.1 gb:NM_006422.1 NM_006422 A kinase (PRKA) anchor protein 3 AKAP3 10566 NM_001278309 /// NM_006422 /// XM_005253664 /// XM_005253665 /// XM_006718951 0006928 // cellular component movement // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007340 // acrosome reaction // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 207345_at NM_006350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006350.2 /DEF=Homo sapiens follistatin (FST), transcript variant FST317, mRNA. /FEA=mRNA /GEN=FST /PROD=follistatin isoform FST317 precursor /DB_XREF=gi:7242223 /UG=Hs.9914 follistatin /FL=gb:NM_006350.2 NM_006350 follistatin FST 10468 NM_006350 /// NM_013409 /// XM_005248400 /// XM_005248401 /// XM_005248402 /// XM_005248403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0051798 // positive regulation of hair follicle development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from physical interaction 207346_at NM_001980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001980.1 /DEF=Homo sapiens epimorphin (EPIM), mRNA. /FEA=mRNA /GEN=EPIM /PROD=epimorphin /DB_XREF=gi:4503586 /UG=Hs.99865 epimorphin /FL=gb:NM_001980.1 NM_001980 syntaxin 2 STX2 2054 NM_001980 /// NM_194356 /// XM_005253556 /// XM_005253557 /// XM_006719276 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007340 // acrosome reaction // inferred from sequence or structural similarity /// 0007398 // ectoderm development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype 0005911 // cell-cell junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity 207347_at NM_000124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000124.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), mRNA. /FEA=mRNA /GEN=ERCC6 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 6 /DB_XREF=gi:4557564 /UG=Hs.99924 excision repair cross-complementing rodent repair deficiency, complementation group 6 /FL=gb:L04791.1 gb:NM_000124.1 NM_000124 excision repair cross-complementation group 6 ERCC6 2074 NM_000124 0000303 // response to superoxide // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007256 // activation of JNKK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 207348_s_at NM_002311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002311.2 /DEF=Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant beta, mRNA. /FEA=mRNA /GEN=LIG3 /PROD=ligase III, DNA, ATP-dependent, isoform beta /DB_XREF=gi:7710127 /UG=Hs.100299 ligase III, DNA, ATP-dependent /FL=gb:U40671.1 gb:NM_002311.2 NM_002311 ligase III, DNA, ATP-dependent LIG3 3980 NM_002311 /// NM_013975 /// XM_005257970 /// XM_005257971 /// XM_006721896 0006260 // DNA replication // inferred from electronic annotation /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006288 // base-excision repair, DNA ligation // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // not recorded /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043504 // mitochondrial DNA repair // inferred from electronic annotation /// 0045910 // negative regulation of DNA recombination // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0005739 // mitochondrion // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003910 // DNA ligase (ATP) activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207349_s_at NM_022803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022803.1 /DEF=Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant short, nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=UCP3 /PROD=uncoupling protein 3, isoform UCP3S /DB_XREF=gi:13259545 /UG=Hs.101337 uncoupling protein 3 (mitochondrial, proton carrier) /FL=gb:NM_022803.1 gb:U82818.1 NM_022803 uncoupling protein 3 (mitochondrial, proton carrier) UCP3 7352 NM_003356 /// NM_022803 0000303 // response to superoxide // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017077 // oxidative phosphorylation uncoupler activity // inferred from electronic annotation 207350_s_at NM_003762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003762.1 /DEF=Homo sapiens vesicle-associated membrane protein 4 (VAMP4), mRNA. /FEA=mRNA /GEN=VAMP4 /PROD=vesicle-associated membrane protein 4 /DB_XREF=gi:4507862 /UG=Hs.102664 vesicle-associated membrane protein 4 /FL=gb:AF044310.1 gb:NM_003762.1 NM_003762 vesicle-associated membrane protein 4 VAMP4 8674 NM_001185127 /// NM_003762 /// NM_201994 /// NR_033704 /// XR_426805 0006887 // exocytosis // not recorded /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035493 // SNARE complex assembly // inferred from direct assay /// 0042996 // regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded 207351_s_at NM_003975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003975.1 /DEF=Homo sapiens SH2 domain protein 2A (SH2D2A), mRNA. /FEA=mRNA /GEN=SH2D2A /PROD=SH2 domain protein 2A /DB_XREF=gi:4503632 /UG=Hs.103527 SH2 domain protein 2A /FL=gb:NM_003975.1 gb:AF097744.1 NM_003975 SH2 domain containing 2A SH2D2A 9047 NM_001161441 /// NM_001161442 /// NM_001161443 /// NM_001161444 /// NM_003975 /// XM_006711615 0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 207352_s_at NM_021911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021911.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 2 (GABRB2), transcript variant 1, mRNA. /FEA=mRNA /GEN=GABRB2 /PROD=gamma-aminobutyric acid (GABA) A receptor, beta2, isoform 1 /DB_XREF=gi:12548784 /UG=Hs.103998 gamma-aminobutyric acid (GABA) A receptor, beta 2 /FL=gb:NM_021911.1 NM_021911 gamma-aminobutyric acid (GABA) A receptor, beta 2 GABRB2 2561 NM_000813 /// NM_021911 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051932 // synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity 0004890 // GABA-A receptor activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005237 // inhibitory extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207353_s_at NM_018942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018942.1 /DEF=Homo sapiens homeo box (H6 family) 1 (HMX1), mRNA. /FEA=mRNA /GEN=HMX1 /PROD=homeo box (H6 family) 1 /DB_XREF=gi:9506784 /UG=Hs.104134 homeo box (H6 family) 1 /FL=gb:M99587.1 gb:NM_018942.1 NM_018942 H6 family homeobox 1 HMX1 3166 NM_018942 /// XM_005248160 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207354_at NM_004590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004590.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 16 (SCYA16), mRNA. /FEA=mRNA /GEN=SCYA16 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 16 /DB_XREF=gi:4759073 /UG=Hs.10458 small inducible cytokine subfamily A (Cys-Cys), member 16 /FL=gb:U91746.1 gb:AB007454.1 gb:AF055467.1 gb:AF039955.1 gb:NM_004590.1 NM_004590 chemokine (C-C motif) ligand 16 CCL16 6360 NM_004590 /// XM_005258020 /// XM_006725334 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay 207355_at NM_006671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006671.1 /DEF=Homo sapiens solute carrier family 1 (glutamate transporter), member 7 (SLC1A7), mRNA. /FEA=mRNA /GEN=SLC1A7 /PROD=solute carrier family 1 (glutamate transporter),member 7 /DB_XREF=gi:10835251 /UG=Hs.104637 solute carrier family 1 (glutamate transporter), member 7 /FL=gb:NM_006671.1 gb:U76362.1 NM_006671 solute carrier family 1 (glutamate transporter), member 7 SLC1A7 6512 NM_001287595 /// NM_001287596 /// NM_001287597 /// NM_006671 /// NR_109858 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0015813 // L-glutamate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 207356_at NM_004942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004942.2 /DEF=Homo sapiens defensin, beta 2 (DEFB2), mRNA. /FEA=mRNA /GEN=DEFB2 /PROD=defensin, beta 2, precursor /DB_XREF=gi:13124885 /UG=Hs.105924 defensin, beta 2 /FL=gb:NM_004942.2 NM_004942 defensin, beta 4A /// defensin, beta 4B DEFB4A /// DEFB4B 1673 /// 100289462 NM_001205266 /// NM_004942 0006935 // chemotaxis // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005796 // Golgi lumen // traceable author statement 207357_s_at NM_017540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017540.1 /DEF=Homo sapiens hypothetical protein DKFZp586H0623 (DKFZp586H0623), mRNA. /FEA=mRNA /GEN=DKFZp586H0623 /PROD=hypothetical protein DKFZp586H0623 /DB_XREF=gi:9055207 /UG=Hs.107260 hypothetical protein DKFZp586H0623 /FL=gb:NM_017540.1 NM_017540 polypeptide N-acetylgalactosaminyltransferase 10 GALNT10 55568 NM_017540 /// NM_024564 /// NM_198321 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207358_x_at NM_012090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012090.1 /DEF=Homo sapiens actin binding protein; macrophin (microfilament and actin filament cross-linker protein) (ACF7), mRNA. /FEA=mRNA /GEN=ACF7 /PROD=actin binding protein; macrophin (microfilamentand actin filament cross-linker protein) /DB_XREF=gi:10048480 /UG=Hs.108258 actin binding protein; macrophin (microfilament and actin filament cross-linker protein) /FL=gb:NM_012090.1 gb:AF141968.1 NM_012090 microtubule-actin crosslinking factor 1 MACF1 23499 NM_012090 /// NM_033044 /// XM_005270694 /// XM_005270695 /// XM_005270696 /// XM_005270697 /// XM_005270698 /// XM_005270700 /// XM_006710519 /// XM_006710520 /// XM_006710521 /// XM_006710522 /// XM_006710523 /// XM_006710524 /// XM_006710525 /// XM_006710526 /// XM_006710527 /// XM_006710528 /// XM_006710529 /// XM_006710530 /// XM_006710531 /// XM_006710532 /// XM_006710533 /// XM_006710534 /// XM_006710535 /// XM_006710536 /// XM_006710537 /// XM_006710538 /// XM_006710539 /// XM_006710540 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010632 // regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // non-traceable author statement 207359_at NM_006549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006549.1 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase kinase 2, beta (CAMKK2), mRNA. /FEA=mRNA /GEN=CAMKK2 /PROD=calciumcalmodulin-dependent protein kinasekinase 2, beta /DB_XREF=gi:5729894 /UG=Hs.108708 calciumcalmodulin-dependent protein kinase kinase 2, beta /FL=gb:AF101264.1 gb:NM_006549.1 NM_006549 calcium/calmodulin-dependent protein kinase kinase 2, beta CAMKK2 10645 NM_001270485 /// NM_001270486 /// NM_006549 /// NM_153499 /// NM_153500 /// NM_172214 /// NM_172215 /// NM_172216 /// NM_172226 /// XM_005253822 /// XM_005253823 /// XM_005253824 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0045859 // regulation of protein kinase activity // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207360_s_at NM_002531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002531.1 /DEF=Homo sapiens neurotensin receptor 1 (high affinity) (NTSR1), mRNA. /FEA=mRNA /GEN=NTSR1 /PROD=neurotensin receptor 1 /DB_XREF=gi:4505476 /UG=Hs.110642 neurotensin receptor 1 (high affinity) /FL=gb:NM_002531.1 NM_002531 neurotensin receptor 1 (high affinity) NTSR1 4923 NM_002531 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016492 // G-protein coupled neurotensin receptor activity // inferred from mutant phenotype 207361_at NM_012257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012257.1 /DEF=Homo sapiens HMG-box containing protein 1 (HBP1), mRNA. /FEA=mRNA /GEN=HBP1 /PROD=HMG-box containing protein 1 /DB_XREF=gi:6912409 /UG=Hs.10882 HMG-box containing protein 1 /FL=gb:AF182038.1 gb:NM_012257.1 NM_012257 HMG-box transcription factor 1 HBP1 26959 NM_001244262 /// NM_012257 /// XM_005250266 /// XM_005250267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207362_at NM_013309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013309.1 /DEF=Homo sapiens solute carrier family 30 (zinc transporter), member 4 (SLC30A4), mRNA. /FEA=mRNA /GEN=SLC30A4 /PROD=solute carrier family 30 (zinc transporter),member 4 /DB_XREF=gi:7019532 /UG=Hs.112282 solute carrier family 30 (zinc transporter), member 4 /FL=gb:AF025409.1 gb:NM_013309.1 NM_013309 solute carrier family 30 (zinc transporter), member 4 SLC30A4 7782 NM_013309 /// XM_005254656 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0055069 // zinc ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061088 // regulation of sequestering of zinc ion // inferred from direct assay /// 0071577 // zinc ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005385 // zinc ion transmembrane transporter activity // traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 207363_at NM_000330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000330.1 /DEF=Homo sapiens retinoschisis (X-linked, juvenile) 1 (RS1), mRNA. /FEA=mRNA /GEN=RS1 /PROD=retinoschisis (X-linked, juvenile) 1 /DB_XREF=gi:10835082 /UG=Hs.113250 retinoschisis (X-linked, juvenile) 1 /FL=gb:NM_000330.1 gb:AF014459.1 NM_000330 retinoschisin 1 RS1 6247 NM_000330 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016062 // adaptation of rhodopsin mediated signaling // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from electronic annotation /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from electronic annotation /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from electronic annotation /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from electronic annotation 207364_at NM_001586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001586.1 /DEF=Homo sapiens chromosome X open reading frame 2 (CXORF2), mRNA. /FEA=mRNA /GEN=CXORF2 /PROD=chromosome X open reading frame 2 /DB_XREF=gi:4503176 /UG=Hs.115365 chromosome X open reading frame 2 /FL=gb:U93720.1 gb:NM_001586.1 NM_001586 testis expressed 28 TEX28 1527 NM_001205201 /// NM_001586 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207365_x_at NM_014709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014709.1 /DEF=Homo sapiens KIAA0570 gene product (KIAA0570), mRNA. /FEA=mRNA /GEN=KIAA0570 /PROD=KIAA0570 gene product /DB_XREF=gi:7662185 /UG=Hs.114293 KIAA0570 gene product /FL=gb:AB011142.1 gb:NM_014709.1 NM_014709 ubiquitin specific peptidase 34 USP34 9736 NM_014709 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0001671 // ATPase activator activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 207366_at NM_002251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002251.2 /DEF=Homo sapiens potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (KCNS1), mRNA. /FEA=mRNA /GEN=KCNS1 /PROD=potassium voltage-gated channel,delayed-rectifier, subfamily S, member 1 /DB_XREF=gi:13492972 /UG=Hs.117780 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 /FL=gb:AF043473.2 gb:NM_002251.2 NM_002251 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 KCNS1 3787 NM_002251 /// XM_005260409 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay 207367_at NM_001676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001676.2 /DEF=Homo sapiens ATPase, H+K+ transporting, nongastric, alpha polypeptide (ATP12A), mRNA. /FEA=mRNA /GEN=ATP12A /PROD=ATPase, H+K+ transporting, nongastric, alphapolypeptide /DB_XREF=gi:10280617 /UG=Hs.1165 ATPase, H+K+ transporting, nongastric, alpha polypeptide /FL=gb:NM_001676.2 gb:U02076.1 NM_001676 ATPase, H+/K+ transporting, nongastric, alpha polypeptide ATP12A 479 NM_001185085 /// NM_001676 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055075 // potassium ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005889 // hydrogen:potassium-exchanging ATPase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008900 // hydrogen:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207368_at NM_000864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000864.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1D (HTR1D), mRNA. /FEA=mRNA /GEN=HTR1D /PROD=5-hydroxytryptamine (serotonin) receptor 1D /DB_XREF=gi:4504534 /UG=Hs.121482 5-hydroxytryptamine (serotonin) receptor 1D /FL=gb:M81589.1 gb:NM_000864.1 NM_000864 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled HTR1D 3352 NM_000864 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014827 // intestine smooth muscle contraction // inferred from mutant phenotype /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from mutant phenotype /// 0051378 // serotonin binding // inferred from electronic annotation 207369_at Z97632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z97632 /DEF=Human DNA sequence from PAC 196E23 on chromosome Xq26.1-27.2. Contains the TAT-SF1 (HIV-1 transcriptional elongation factor TAT cofactor TAT-SF1) gene, the BRS3 (Bombesin Receptor subtype-3 (Uterine Bombesin Receptor, BRS-3) gene, an unknown gene ... /FEA=mRNA_2 /DB_XREF=gi:2808417 /UG=Hs.121484 bombesin-like receptor 3 /FL=gb:L08893.1 gb:NM_001727.1 Z97632 bombesin-like receptor 3 BRS3 680 NM_001727 /// XM_005262464 /// XM_005262465 0006006 // glucose metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0008343 // adult feeding behavior // traceable author statement /// 0031989 // bombesin receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004946 // bombesin receptor activity // inferred from electronic annotation 207370_at NM_004967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004967.2 /DEF=Homo sapiens integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) (IBSP), mRNA. /FEA=mRNA /GEN=IBSP /PROD=integrin-binding sialoprotein precursor /DB_XREF=gi:13259536 /UG=Hs.121552 integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) /FL=gb:NM_004967.2 gb:J05213.1 NM_004967 integrin-binding sialoprotein IBSP 3381 NM_004967 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0031988 // membrane-bounded vesicle // inferred from sequence or structural similarity 207371_at NM_017513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017513.1 /DEF=Homo sapiens metaphase chromosome protein 1 (HSMCR30), mRNA. /FEA=mRNA /GEN=HSMCR30 /PROD=metaphase chromosome protein 1 /DB_XREF=gi:8923780 /UG=Hs.122744 metaphase chromosome protein 1 /FL=gb:NM_017513.1 NM_017513 0006260 // DNA replication // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 207372_s_at NM_001246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001246.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2), mRNA. /FEA=mRNA /GEN=ENTPD2 /PROD=ectonucleoside triphosphate diphosphohydrolase2 /DB_XREF=gi:4557420 /UG=Hs.123036 ectonucleoside triphosphate diphosphohydrolase 2 /FL=gb:U91510.1 gb:NM_001246.1 NM_001246 ectonucleoside triphosphate diphosphohydrolase 2 ENTPD2 954 NM_001246 /// NM_203468 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation 0005605 // basal lamina // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207373_at NM_002148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002148.1 /DEF=Homo sapiens homeo box D10 (HOXD10), mRNA. /FEA=mRNA /GEN=HOXD10 /PROD=homeo box D10 /DB_XREF=gi:4504470 /UG=Hs.123070 homeo box D10 /FL=gb:NM_002148.1 NM_002148 homeobox D10 HOXD10 3236 NM_002148 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0021520 // spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207374_at NM_020359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020359.1 /DEF=Homo sapiens phospholipid scramblase 2 (PLSCR2), mRNA. /FEA=mRNA /GEN=PLSCR2 /PROD=phospholipid scramblase 2 /DB_XREF=gi:9966794 /UG=Hs.123411 phospholipid scramblase 2 /FL=gb:AF159441.1 gb:NM_020359.1 NM_020359 phospholipid scramblase 2 PLSCR2 57047 NM_001199978 /// NM_001199979 /// NM_020359 /// XM_006713712 0017121 // phospholipid scrambling // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0017128 // phospholipid scramblase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207375_s_at NM_002189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002189.1 /DEF=Homo sapiens interleukin 15 receptor, alpha (IL15RA), mRNA. /FEA=mRNA /GEN=IL15RA /PROD=interleukin 15 receptor, alpha /DB_XREF=gi:4504648 /UG=Hs.12503 interleukin 15 receptor, alpha /FL=gb:U31628.1 gb:NM_002189.1 NM_002189 interleukin 15 receptor, alpha IL15RA 3601 NM_001243539 /// NM_001256765 /// NM_002189 /// NM_172200 /// NR_046362 /// XM_006717441 /// XM_006717442 /// XM_006717443 /// XM_006717444 /// XM_006717445 /// XM_006717446 /// XM_006717447 0007165 // signal transduction // traceable author statement /// 0007259 // JAK-STAT cascade // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004896 // cytokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207376_at NM_014468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014468.1 /DEF=Homo sapiens haemopoietic progenitor homeobox (HPX42B), mRNA. /FEA=mRNA /GEN=HPX42B /PROD=haemopoietic progenitor homeobox /DB_XREF=gi:7657179 /UG=Hs.125231 haemopoietic progenitor homeobox /FL=gb:AF068006.1 gb:NM_014468.1 NM_014468 VENT homeobox VENTX 27287 NM_014468 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207377_at NM_025210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025210.1 /DEF=Homo sapiens type 1 protein phosphatase inhibitor (I-4), mRNA. /FEA=mRNA /GEN=I-4 /PROD=type 1 protein phosphatase inhibitor /DB_XREF=gi:13376811 /UG=Hs.127689 type 1 protein phosphatase inhibitor /FL=gb:AB044137.1 gb:NM_025210.1 NM_025210 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 PPP1R2P9 80316 NM_025210 /// NR_002191 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // non-traceable author statement 207378_at NM_007180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007180.1 /DEF=Homo sapiens trehalase (brush-border membrane glycoprotein) (TREH), mRNA. /FEA=mRNA /GEN=TREH /PROD=trehalase (brush-border membrane glycoprotein) /DB_XREF=gi:6005913 /UG=Hs.129712 trehalase (brush-border membrane glycoprotein) /FL=gb:AB000824.1 gb:NM_007180.1 NM_007180 trehalase (brush-border membrane glycoprotein) TREH 11181 NM_007180 /// XM_005277678 0005975 // carbohydrate metabolic process // traceable author statement /// 0005991 // trehalose metabolic process // non-traceable author statement /// 0005993 // trehalose catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0044245 // polysaccharide digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004555 // alpha,alpha-trehalase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 207379_at NM_005711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005711.1 /DEF=Homo sapiens EGF-like repeats and discoidin I-like domains 3 (EDIL3), mRNA. /FEA=mRNA /GEN=EDIL3 /PROD=EGF-like repeats and discoidin I-like domains 3 /DB_XREF=gi:5031660 /UG=Hs.129764 EGF-like repeats and discoidin I-like domains 3 /FL=gb:U70312.1 gb:NM_005711.1 NM_005711 EGF-like repeats and discoidin I-like domains 3 EDIL3 10085 NM_001278642 /// NM_005711 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207380_x_at NM_013954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013954.1 /DEF=Homo sapiens NADPH oxidase 1 (NOX1), transcript variant NOH-1S, mRNA. /FEA=mRNA /GEN=NOX1 /PROD=NADPH oxidase 1 isoform short /DB_XREF=gi:7669507 /UG=Hs.132370 NADPH oxidase 1 /FL=gb:AF166326.1 gb:NM_013954.1 NM_013954 NADPH oxidase 1 NOX1 27035 NM_001271815 /// NM_007052 /// NM_013954 /// NM_013955 0001525 // angiogenesis // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred by curator /// 0006746 // FADH2 metabolic process // non-traceable author statement /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006811 // ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009268 // response to pH // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from expression pattern /// 0015992 // proton transport // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042743 // hydrogen peroxide metabolic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from direct assay /// 0072592 // oxygen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred by curator /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030171 // voltage-gated proton channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0050661 // NADP binding // inferred by curator 207381_at NM_001139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001139.1 /DEF=Homo sapiens arachidonate 12-lipoxygenase, 12R type (ALOX12B), mRNA. /FEA=mRNA /GEN=ALOX12B /PROD=arachidonate 12-lipoxygenase, 12R type /DB_XREF=gi:4502052 /UG=Hs.136574 arachidonate 12-lipoxygenase, 12R type /FL=gb:AF038461.1 gb:AF059250.1 gb:NM_001139.1 NM_001139 arachidonate 12-lipoxygenase, 12R type ALOX12B 242 NM_001139 0006497 // protein lipidation // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // inferred from direct assay /// 0019372 // lipoxygenase pathway // inferred from mutant phenotype /// 0019372 // lipoxygenase pathway // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043651 // linoleic acid metabolic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from sequence or structural similarity /// 0051122 // hepoxilin biosynthetic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0070257 // positive regulation of mucus secretion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004052 // arachidonate 12-lipoxygenase activity // inferred from mutant phenotype /// 0004052 // arachidonate 12-lipoxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 1990136 // linoleate 9S-lipoxygenase activity // inferred from sequence or structural similarity 207382_at NM_003722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003722.1 /DEF=Homo sapiens tumor protein 63 kDa with strong homology to p53 (TP63), mRNA. /FEA=mRNA /GEN=TP63 /PROD=tumor protein 63 kDa with strong homology top53 /DB_XREF=gi:4507638 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AB016072.1 gb:AF075428.1 gb:AF075429.1 gb:NM_003722.1 NM_003722 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 207383_s_at NM_003961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003961.1 /DEF=Homo sapiens rhomboid (veinlet, Drosophila)-like (RHBDL), mRNA. /FEA=mRNA /GEN=RHBDL /PROD=rhomboid (veinlet, Drosophila)-like /DB_XREF=gi:4506524 /UG=Hs.137572 rhomboid (veinlet, Drosophila)-like /FL=gb:Y17108.1 gb:NM_003961.1 NM_003961 rhomboid, veinlet-like 1 (Drosophila) RHBDL1 9028 NM_001278720 /// NM_001278721 /// NM_003961 /// XM_005255665 /// XM_005255666 /// XM_006720974 /// XM_006720975 0006508 // proteolysis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207384_at NM_005091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005091.1 /DEF=Homo sapiens peptidoglycan recognition protein (PGLYRP), mRNA. /FEA=mRNA /GEN=PGLYRP /PROD=peptidoglycan recognition protein /DB_XREF=gi:4827035 /UG=Hs.137583 peptidoglycan recognition protein /FL=gb:AF076483.1 gb:NM_005091.1 gb:AF242517.1 NM_005091 peptidoglycan recognition protein 1 PGLYRP1 8993 NM_005091 0002221 // pattern recognition receptor signaling pathway // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009253 // peptidoglycan catabolic process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032827 // negative regulation of natural killer cell differentiation involved in immune response // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0044117 // growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // non-traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0008745 // N-acetylmuramoyl-L-alanine amidase activity // inferred from electronic annotation /// 0016019 // peptidoglycan receptor activity // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 207385_at NM_016521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016521.1 /DEF=Homo sapiens E2F-like protein (LOC51270), mRNA. /FEA=mRNA /GEN=LOC51270 /PROD=E2F-like protein /DB_XREF=gi:7706068 /UG=Hs.142908 E2F-like protein /FL=gb:AF219119.1 gb:NM_016521.1 NM_016521 transcription factor Dp family, member 3 TFDP3 51270 NM_016521 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 207386_at NM_004820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004820.2 /DEF=Homo sapiens cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1 (CYP7B1), mRNA. /FEA=mRNA /GEN=CYP7B1 /PROD=cytochrome P450, subfamily VIIB, polypeptide 1 /DB_XREF=gi:13787190 /UG=Hs.144877 cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1 /FL=gb:NM_004820.2 gb:AF029403.1 gb:AF127090.1 NM_004820 cytochrome P450, family 7, subfamily B, polypeptide 1 CYP7B1 9420 NM_004820 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008396 // oxysterol 7-alpha-hydroxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0033783 // 25-hydroxycholesterol 7alpha-hydroxylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207387_s_at NM_000167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000167.1 /DEF=Homo sapiens glycerol kinase (GK), mRNA. /FEA=mRNA /GEN=GK /PROD=glycerol kinase /DB_XREF=gi:4504006 /UG=Hs.1466 glycerol kinase /FL=gb:L13943.1 gb:NM_000167.1 NM_000167 glycerol kinase GK 2710 NM_000167 /// NM_001128127 /// NM_001205019 /// NM_203391 /// XM_005274488 /// XM_006724483 /// XM_006724484 /// XM_006724485 /// XM_006724486 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from mutant phenotype /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046167 // glycerol-3-phosphate biosynthetic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // inferred from mutant phenotype /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 207388_s_at NM_004878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004878.1 /DEF=Homo sapiens prostaglandin E synthase (PTGES), mRNA. /FEA=mRNA /GEN=PTGES /PROD=prostaglandin E synthase /DB_XREF=gi:4758909 /UG=Hs.146688 prostaglandin E synthase /FL=gb:AF027740.1 gb:NM_004878.1 NM_004878 prostaglandin E synthase PTGES 9536 NM_004878 /// NM_198797 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0016853 // isomerase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from direct assay /// 0050220 // prostaglandin-E synthase activity // not recorded /// 0050220 // prostaglandin-E synthase activity // inferred from direct assay 207389_at NM_000173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000173.1 /DEF=Homo sapiens glycoprotein Ib (platelet), alpha polypeptide (GP1BA), mRNA. /FEA=mRNA /GEN=GP1BA /PROD=platelet glycoprotein Ib alpha polypeptideprecursor /DB_XREF=gi:4504070 /UG=Hs.1472 glycoprotein Ib (platelet), alpha polypeptide /FL=gb:J02940.1 gb:NM_000173.1 NM_000173 glycoprotein Ib (platelet), alpha polypeptide GP1BA 2811 NM_000173 0000902 // cell morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // traceable author statement /// 0042730 // fibrinolysis // inferred from direct assay /// 0070493 // thrombin receptor signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // traceable author statement 207390_s_at NM_006932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006932.1 /DEF=Homo sapiens smoothelin (SMTN), mRNA. /FEA=mRNA /GEN=SMTN /PROD=smoothelin /DB_XREF=gi:5902099 /UG=Hs.149098 smoothelin /FL=gb:NM_006932.1 NM_006932 smoothelin SMTN 6525 NM_001207017 /// NM_001207018 /// NM_006932 /// NM_134269 /// NM_134270 /// XM_006724298 /// XM_006724299 /// XM_006724300 /// XM_006724301 /// XM_006724302 /// XM_006724303 /// XM_006724304 /// XM_006724305 /// XM_006724306 /// XM_006724307 /// XR_430410 0006939 // smooth muscle contraction // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement 207391_s_at NM_003557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003557.1 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (PIP5K1A), mRNA. /FEA=mRNA /GEN=PIP5K1A /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeI, alpha /DB_XREF=gi:4505814 /UG=Hs.149255 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha /FL=gb:U78575.1 gb:NM_003557.1 NM_003557 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha PIP5K1A 8394 NM_001135636 /// NM_001135637 /// NM_001135638 /// NM_003557 /// XM_005245525 /// XM_005245526 /// XM_005245527 /// XM_005245528 /// XM_005245529 /// XM_005245530 /// XM_005245531 /// XM_005245532 /// XM_006711563 /// XM_006711564 /// XM_006711565 /// XM_006711566 /// XM_006711567 /// XM_006711568 0006644 // phospholipid metabolic process // traceable author statement /// 0006650 // glycerophospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006909 // phagocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from direct assay /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement /// 0030216 // keratinocyte differentiation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0097178 // ruffle assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay 207392_x_at NM_001076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001076.1 /DEF=Homo sapiens UDP glycosyltransferase 2 family, polypeptide B15 (UGT2B15), mRNA. /FEA=mRNA /GEN=UGT2B15 /PROD=UDP glycosyltransferase 2 family, polypeptideB15 /DB_XREF=gi:4507818 /UG=Hs.150207 UDP glycosyltransferase 2 family, polypeptide B15 /FL=gb:NM_001076.1 gb:U08854.1 gb:AF180322.1 NM_001076 UDP glucuronosyltransferase 2 family, polypeptide B15 UGT2B15 7366 NM_001076 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0052695 // cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 207393_at NM_001526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001526.2 /DEF=Homo sapiens hypocretin (orexin) receptor 2 (HCRTR2), mRNA. /FEA=mRNA /GEN=HCRTR2 /PROD=orexin receptor 2 /DB_XREF=gi:6006037 /UG=Hs.151624 hypocretin (orexin) receptor 2 /FL=gb:AF041245.1 gb:NM_001526.2 NM_001526 hypocretin (orexin) receptor 2 HCRTR2 3062 NM_001526 /// XM_006715074 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007631 // feeding behavior // inferred from electronic annotation /// 0022410 // circadian sleep/wake cycle process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008188 // neuropeptide receptor activity // traceable author statement /// 0016499 // orexin receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation 207394_at NM_003438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003438.1 /DEF=Homo sapiens zinc finger protein 137 (clone pHZ-30) (ZNF137), mRNA. /FEA=mRNA /GEN=ZNF137 /PROD=zinc finger protein 137 (clone pHZ-30) /DB_XREF=gi:4507988 /UG=Hs.151689 zinc finger protein 137 (clone pHZ-30) /FL=gb:NM_003438.1 gb:U09414.1 NM_003438 zinc finger protein 137, pseudogene ZNF137P 7696 NM_003438 /// NR_023311 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207395_at NM_001732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001732.1 /DEF=Homo sapiens butyrophilin, subfamily 1, member A1 (BTN1A1), mRNA. /FEA=mRNA /GEN=BTN1A1 /PROD=butyrophilin, subfamily 1, member A1 /DB_XREF=gi:4502474 /UG=Hs.153058 butyrophilin, subfamily 1, member A1 /FL=gb:U39576.1 gb:NM_001732.1 NM_001732 butyrophilin, subfamily 1, member A1 BTN1A1 696 NM_001732 /// XM_005249340 /// XM_005249341 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207396_s_at NM_005787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005787.1 /DEF=Homo sapiens Not56 (D. melanogaster)-like protein (NOT56L), mRNA. /FEA=mRNA /GEN=NOT56L /PROD=Not56 (D. melanogaster)-like protein /DB_XREF=gi:5031952 /UG=Hs.153591 Not56 (D. melanogaster)-like protein /FL=gb:BC002839.1 gb:NM_005787.1 NM_005787 ALG3, alpha-1,3- mannosyltransferase ALG3 10195 NM_001006940 /// NM_001006941 /// NM_005787 /// NR_024533 /// NR_024534 0006486 // protein glycosylation // non-traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from direct assay /// 0097502 // mannosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000033 // alpha-1,3-mannosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0052925 // dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity // inferred from electronic annotation 207397_s_at NM_000523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000523.1 /DEF=Homo sapiens homeo box D13 (HOXD13), mRNA. /FEA=mRNA /GEN=HOXD13 /PROD=homeo box D13 /DB_XREF=gi:9624999 /UG=Hs.158309 homeo box D13 /FL=gb:NM_000523.1 NM_000523 homeobox D13 HOXD13 3239 NM_000523 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0060602 // branch elongation of an epithelium // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207398_at NM_000523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000523.1 /DEF=Homo sapiens homeo box D13 (HOXD13), mRNA. /FEA=mRNA /GEN=HOXD13 /PROD=homeo box D13 /DB_XREF=gi:9624999 /UG=Hs.158309 homeo box D13 /FL=gb:NM_000523.1 NM_000523 homeobox D13 HOXD13 3239 NM_000523 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0060602 // branch elongation of an epithelium // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207399_at NM_003571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003571.1 /DEF=Homo sapiens beaded filament structural protein 2, phakinin (BFSP2), mRNA. /FEA=mRNA /GEN=BFSP2 /PROD=phakinin /DB_XREF=gi:4502994 /UG=Hs.158321 beaded filament structural protein 2, phakinin /FL=gb:U48224.1 gb:NM_003571.1 NM_003571 beaded filament structural protein 2, phakinin BFSP2 8419 NM_003571 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207400_at NM_006174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006174.1 /DEF=Homo sapiens neuropeptide Y receptor Y5 (NPY5R), mRNA. /FEA=mRNA /GEN=NPY5R /PROD=neuropeptide Y receptor Y5 /DB_XREF=gi:5453795 /UG=Hs.158330 neuropeptide Y receptor Y5 /FL=gb:U56079.1 gb:U66275.1 gb:U94320.1 gb:NM_006174.1 NM_006174 neuropeptide Y receptor Y5 NPY5R 4889 NM_006174 /// XM_005263036 /// XM_005263037 /// XM_005263038 /// XM_005263039 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0060112 // generation of ovulation cycle rhythm // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0001602 // pancreatic polypeptide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // traceable author statement 207401_at NM_002763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002763.1 /DEF=Homo sapiens prospero-related homeobox 1 (PROX1), mRNA. /FEA=mRNA /GEN=PROX1 /PROD=prospero-related homeobox 1 /DB_XREF=gi:4506118 /UG=Hs.159437 prospero-related homeobox 1 /FL=gb:U44060.1 gb:NM_002763.1 NM_002763 prospero homeobox 1 PROX1 5629 NM_001270616 /// NM_002763 /// XM_005273194 /// XM_005273195 /// XM_005273196 /// XM_006711455 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001822 // kidney development // inferred from expression pattern /// 0001889 // liver development // inferred from expression pattern /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0001946 // lymphangiogenesis // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from expression pattern /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002194 // hepatocyte cell migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from expression pattern /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0021516 // dorsal spinal cord development // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from sequence or structural similarity /// 0030240 // skeletal muscle thin filament assembly // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from expression pattern /// 0030910 // olfactory placode formation // inferred from sequence or structural similarity /// 0031016 // pancreas development // inferred from expression pattern /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0043049 // otic placode formation // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046619 // optic placode formation involved in camera-type eye formation // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from electronic annotation /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055005 // ventricular cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060042 // retina morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from expression pattern /// 0060214 // endocardium formation // inferred from sequence or structural similarity /// 0060298 // positive regulation of sarcomere organization // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060414 // aorta smooth muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060421 // positive regulation of heart growth // inferred from sequence or structural similarity /// 0060836 // lymphatic endothelial cell differentiation // inferred from direct assay /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype /// 0070309 // lens fiber cell morphogenesis // inferred from expression pattern /// 0070365 // hepatocyte differentiation // inferred from expression pattern /// 0070858 // negative regulation of bile acid biosynthetic process // inferred from mutant phenotype /// 0072574 // hepatocyte proliferation // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity /// 1901978 // positive regulation of cell cycle checkpoint // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from sequence or structural similarity /// 2000979 // positive regulation of forebrain neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0050692 // DBD domain binding // inferred from physical interaction /// 0050693 // LBD domain binding // inferred from physical interaction 207402_at NM_003433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003433.1 /DEF=Homo sapiens zinc finger protein 132 (clone pHZ-12) (ZNF132), mRNA. /FEA=mRNA /GEN=ZNF132 /PROD=zinc finger protein 132 (clone pHZ-12) /DB_XREF=gi:4507978 /UG=Hs.159468 zinc finger protein 132 (clone pHZ-12) /FL=gb:NM_003433.1 gb:U09411.1 NM_003433 zinc finger protein 132 ZNF132 7691 NM_003433 /// XM_005259210 /// XM_006723361 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207403_at NM_003604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003604.1 /DEF=Homo sapiens insulin receptor substrate 4 (IRS4), mRNA. /FEA=mRNA /GEN=IRS4 /PROD=insulin receptor substrate 4 /DB_XREF=gi:4504732 /UG=Hs.159609 insulin receptor substrate 4 /FL=gb:AF007567.1 gb:NM_003604.1 NM_003604 insulin receptor substrate 4 IRS4 8471 NM_003604 /// XM_005262220 /// XM_006724713 0007165 // signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 207404_s_at NM_000865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000865.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1E (HTR1E), mRNA. /FEA=mRNA /GEN=HTR1E /PROD=5-hydroxytryptamine (serotonin) receptor 1E /DB_XREF=gi:4504536 /UG=Hs.1611 5-hydroxytryptamine (serotonin) receptor 1E /FL=gb:M91467.1 gb:NM_000865.1 NM_000865 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled HTR1E 3354 NM_000865 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0030815 // negative regulation of cAMP metabolic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0004993 // serotonin receptor activity // inferred from mutant phenotype /// 0051378 // serotonin binding // inferred from direct assay 207405_s_at NM_002873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002873.1 /DEF=Homo sapiens RAD17 (S. pombe) homolog (RAD17), mRNA. /FEA=mRNA /GEN=RAD17 /PROD=RAD17 (S. pombe) homolog /DB_XREF=gi:4506382 /UG=Hs.16184 RAD17 (S. pombe) homolog /FL=gb:AF076838.1 gb:NM_002873.1 NM_002873 RAD17 homolog (S. pombe) RAD17 5884 NM_001278622 /// NM_002873 /// NM_133338 /// NM_133339 /// NM_133340 /// NM_133341 /// NM_133342 /// NM_133343 /// NM_133344 /// XM_005276774 0000076 // DNA replication checkpoint // traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207406_at NM_000780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000780.2 /DEF=Homo sapiens cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1 (CYP7A1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CYP7A1 /PROD=cytochrome P450, subfamily VIIA, polypeptide 1 /DB_XREF=gi:13787185 /UG=Hs.1644 cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1 /FL=gb:NM_000780.2 gb:M93133.1 NM_000780 cytochrome P450, family 7, subfamily A, polypeptide 1 CYP7A1 1581 NM_000780 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from sequence or structural similarity /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006707 // cholesterol catabolic process // inferred from sequence or structural similarity /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070857 // regulation of bile acid biosynthetic process // inferred from direct assay /// 0070857 // regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008123 // cholesterol 7-alpha-monooxygenase activity // inferred from sequence or structural similarity /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207407_x_at NM_000778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000778.2 /DEF=Homo sapiens cytochrome P450, subfamily IVA, polypeptide 11 (CYP4A11), mRNA. /FEA=mRNA /GEN=CYP4A11 /PROD=cytochrome P450, subfamily IVA, polypeptide 11 /DB_XREF=gi:13435387 /UG=Hs.1645 cytochrome P450, subfamily IVA, polypeptide 11 /FL=gb:NM_000778.2 gb:L04751.1 NM_000778 cytochrome P450, family 4, subfamily A, polypeptide 11 CYP4A11 1579 NM_000778 /// XM_005270537 /// XM_005270538 /// XM_005270539 /// XM_006710392 /// XR_246241 /// XR_246242 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0003091 // renal water homeostasis // inferred from expression pattern /// 0003095 // pressure natriuresis // inferred from expression pattern /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0032305 // positive regulation of icosanoid secretion // inferred from mutant phenotype /// 0036101 // leukotriene B4 catabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from direct assay /// 0052869 // arachidonic acid omega-hydroxylase activity // inferred from electronic annotation 207408_at NM_004803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004803.2 /DEF=Homo sapiens organic cationic transporter-like 4 (ORCTL4), mRNA. /FEA=mRNA /GEN=ORCTL4 /PROD=organic cation transporter like 4 /DB_XREF=gi:13699860 /UG=Hs.165559 organic cationic transporter-like 4 /FL=gb:NM_004803.2 gb:AB011082.1 NM_004803 solute carrier family 22, member 14 SLC22A14 9389 NM_004803 /// XM_005265584 /// XM_005265585 /// XM_006713416 /// XM_006713417 /// XM_006713418 0015695 // organic cation transport // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015101 // organic cation transmembrane transporter activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 207409_at NM_002302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002302.1 /DEF=Homo sapiens leukocyte cell-derived chemotaxin 2 (LECT2), mRNA. /FEA=mRNA /GEN=LECT2 /PROD=leukocyte cell-derived chemotaxin 2 /DB_XREF=gi:4504976 /UG=Hs.167877 leukocyte cell-derived chemotaxin 2 /FL=gb:D63521.1 gb:NM_002302.1 NM_002302 leukocyte cell-derived chemotaxin 2 LECT2 3950 NM_002302 0001501 // skeletal system development // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0042802 // identical protein binding // inferred from physical interaction 207410_s_at NM_016170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016170.1 /DEF=Homo sapiens NCX protein (NCX), mRNA. /FEA=mRNA /GEN=NCX /PROD=NCX protein /DB_XREF=gi:7706620 /UG=Hs.168586 NCX protein /FL=gb:AB008501.1 gb:NM_016170.1 NM_016170 T-cell leukemia homeobox 2 TLX2 3196 NM_016170 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050774 // negative regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207412_x_at NM_001808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001808.1 /DEF=Homo sapiens carboxyl ester lipase-like (bile salt-stimulated lipase-like) (CELL), mRNA. /FEA=mRNA /GEN=CELL /PROD=carboxyl ester lipase-like (bile salt-stimulatedlipase-like) /DB_XREF=gi:4502772 /UG=Hs.169271 carboxyl ester lipase-like (bile salt-stimulated lipase-like) /FL=gb:L14813.1 gb:NM_001808.1 NM_001808 carboxyl ester lipase pseudogene CELP 1057 NR_001275 207413_s_at NM_000335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000335.1 /DEF=Homo sapiens sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3) (SCN5A), mRNA. /FEA=mRNA /GEN=SCN5A /PROD=sodium channel, voltage-gated, type V, alphapolypeptide /DB_XREF=gi:4506808 /UG=Hs.169331 sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3) /FL=gb:M77235.1 gb:NM_000335.1 NM_000335 sodium channel, voltage-gated, type V, alpha subunit SCN5A 6331 NM_000335 /// NM_001099404 /// NM_001099405 /// NM_001160160 /// NM_001160161 /// NM_198056 /// XM_006713282 /// XM_006713283 /// XM_006713284 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003231 // cardiac ventricle development // inferred from sequence or structural similarity /// 0003360 // brainstem development // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from direct assay /// 0010765 // positive regulation of sodium ion transport // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0019228 // neuronal action potential // not recorded /// 0021537 // telencephalon development // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0045760 // positive regulation of action potential // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051899 // membrane depolarization // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086004 // regulation of cardiac muscle cell contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086046 // membrane depolarization during SA node cell action potential // inferred from sequence or structural similarity /// 0086067 // AV node cell to bundle of His cell communication // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1902305 // regulation of sodium ion transmembrane transport // inferred from direct assay 0001518 // voltage-gated sodium channel complex // inferred by curator /// 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0005901 // caveola // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // traceable author statement /// 0030315 // T-tubule // inferred from direct assay /// 0034706 // sodium channel complex // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from direct assay /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype /// 0086063 // voltage-gated sodium channel activity involved in SA node cell action potential // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction 207414_s_at NM_002570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002570.1 /DEF=Homo sapiens paired basic amino acid cleaving system 4 (PACE4), mRNA. /FEA=mRNA /GEN=PACE4 /PROD=paired basic amino acid cleaving system 4 /DB_XREF=gi:4505576 /UG=Hs.170414 paired basic amino acid cleaving system 4 /FL=gb:M80482.1 gb:NM_002570.1 NM_002570 uncharacterized LOC100507472 /// proprotein convertase subtilisin/kexin type 6 LOC100507472 /// PCSK6 5046 /// 100507472 NM_001291309 /// NM_002570 /// NM_138319 /// NM_138320 /// NM_138321 /// NM_138322 /// NM_138323 /// NM_138324 /// NM_138325 /// NR_045387 0006508 // proteolysis // inferred from electronic annotation /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032940 // secretion by cell // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 207415_at NM_007366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007366.1 /DEF=Homo sapiens phospholipase A2 receptor 1, 180kD (PLA2R1), mRNA. /FEA=mRNA /GEN=PLA2R1 /PROD=phospholipase A2 receptor 1, 180kD /DB_XREF=gi:6679370 /UG=Hs.171945 phospholipase A2 receptor 1, 180kD /FL=gb:NM_007366.1 gb:U17034.1 NM_007366 phospholipase A2 receptor 1, 180kDa PLA2R1 22925 NM_001007267 /// NM_001195641 /// NM_007366 /// XM_005246392 /// XM_005246393 /// XM_005246395 /// XM_006712369 0001816 // cytokine production // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 1900138 // negative regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 1900139 // negative regulation of arachidonic acid secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 207416_s_at NM_004555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004555.1 /DEF=Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (NFATC3), mRNA. /FEA=mRNA /GEN=NFATC3 /PROD=nuclear factor of activated T-cells,cytoplasmic, calcineurin-dependent 3 /DB_XREF=gi:4758803 /UG=Hs.172674 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 /FL=gb:U85428.1 gb:NM_004555.1 gb:L41067.1 NM_004555 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFATC3 4775 NM_004555 /// NM_173163 /// NM_173164 /// NM_173165 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045333 // cellular respiration // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207417_s_at NM_003451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003451.1 /DEF=Homo sapiens zinc finger protein 177 (ZNF177), mRNA. /FEA=mRNA /GEN=ZNF177 /PROD=zinc finger protein 177 /DB_XREF=gi:4508008 /UG=Hs.172979 zinc finger protein 177 /FL=gb:U37263.1 gb:NM_003451.1 NM_003451 zinc finger protein 177 /// ZNF559-ZNF177 readthrough ZNF177 /// ZNF559-ZNF177 7730 /// 100529215 NM_001172650 /// NM_001172651 /// NM_001202425 /// NM_003451 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207418_s_at NM_003649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003649.1 /DEF=Homo sapiens D-aspartate oxidase (DDO), transcript variant 1, mRNA. /FEA=mRNA /GEN=DDO /PROD=D-aspartate oxidase isoform a /DB_XREF=gi:4503288 /UG=Hs.174441 D-aspartate oxidase /FL=gb:D89858.1 gb:NM_003649.1 NM_003649 D-aspartate oxidase DDO 8528 NM_003649 /// NM_004032 0006531 // aspartate metabolic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0007320 // insemination // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0019478 // D-amino acid catabolic process // inferred from direct assay /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // non-traceable author statement 0003884 // D-amino-acid oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008445 // D-aspartate oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay 207419_s_at NM_002872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002872.2 /DEF=Homo sapiens ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2), mRNA. /FEA=mRNA /GEN=RAC2 /PROD=ras-related C3 botulinum toxin substrate 2 /DB_XREF=gi:9845512 /UG=Hs.173466 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) /FL=gb:NM_002872.2 NM_002872 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) RAC2 5880 NM_002872 /// XM_006724286 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010310 // regulation of hydrogen peroxide metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0045453 // bone resorption // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0060263 // regulation of respiratory burst // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 207420_at NM_006438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006438.1 /DEF=Homo sapiens collectin sub-family member 10 (C-type lectin) (COLEC10), mRNA. /FEA=mRNA /GEN=COLEC10 /PROD=collectin sub-family member 10 (C-type lectin) /DB_XREF=gi:5453618 /UG=Hs.176615 collectin sub-family member 10 (C-type lectin) /FL=gb:AB002631.1 gb:NM_006438.1 NM_006438 collectin sub-family member 10 (C-type lectin) COLEC10 10584 NM_006438 /// XM_005250756 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005537 // mannose binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 207421_at NM_001739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001739.1 /DEF=Homo sapiens carbonic anhydrase VA, mitochondrial (CA5A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CA5A /PROD=carbonic anhydrase VA, mitochondrial precursor /DB_XREF=gi:4502520 /UG=Hs.177446 carbonic anhydrase VA, mitochondrial /FL=gb:L19297.1 gb:NM_001739.1 NM_001739 carbonic anhydrase VA, mitochondrial CA5A 763 NM_001739 /// XM_005256134 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207422_at NM_003814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003814.2 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 20 (ADAM20), mRNA. /FEA=mRNA /GEN=ADAM20 /PROD=a disintegrin and metalloproteinase domain 20preproprotein /DB_XREF=gi:11497037 /UG=Hs.177984 a disintegrin and metalloproteinase domain 20 /FL=gb:NM_003814.2 gb:AF029899.1 NM_003814 ADAM metallopeptidase domain 20 ADAM20 8748 NM_003814 /// XM_005268151 /// XM_005268152 0006508 // proteolysis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207423_s_at AF029899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029899.1 /DEF=Homo sapiens ADAM 20 mRNA, complete cds. /FEA=mRNA /PROD=ADAM 20 /DB_XREF=gi:2739134 /UG=Hs.177984 a disintegrin and metalloproteinase domain 20 /FL=gb:NM_003814.2 gb:AF029899.1 AF029899 ADAM metallopeptidase domain 20 ADAM20 8748 NM_003814 /// XM_005268151 /// XM_005268152 0006508 // proteolysis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207424_at NM_005593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005593.1 /DEF=Homo sapiens myogenic factor 5 (MYF5), mRNA. /FEA=mRNA /GEN=MYF5 /PROD=myogenic factor 5 /DB_XREF=gi:5031928 /UG=Hs.178023 myogenic factor 5 /FL=gb:NM_005593.1 NM_005593 myogenic factor 5 MYF5 4617 NM_005593 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 207425_s_at NM_006640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006640.1 /DEF=Homo sapiens MLL septin-like fusion (MSF), mRNA. /FEA=mRNA /GEN=MSF /PROD=MLL septin-like fusion /DB_XREF=gi:5729932 /UG=Hs.181002 MLL septin-like fusion /FL=gb:AF123052.1 gb:NM_006640.1 NM_006640 septin 9 SEPT9 10801 NM_001113491 /// NM_001113492 /// NM_001113493 /// NM_001113494 /// NM_001113495 /// NM_001113496 /// NM_001293695 /// NM_001293696 /// NM_001293697 /// NM_001293698 /// NM_006640 /// XM_005256959 /// XM_005256960 /// XM_005256961 /// XM_005256962 /// XM_006721643 /// XM_006721644 0006184 // GTP catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 207426_s_at NM_003326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003326.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kD) (TNFSF4), mRNA. /FEA=mRNA /GEN=TNFSF4 /PROD=tumor necrosis factor (ligand) superfamily,member 4 (tax-transcriptionally activated glycoprotein 1,34kD) /DB_XREF=gi:4507602 /UG=Hs.181097 tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kD) /FL=gb:NM_003326.1 NM_003326 tumor necrosis factor (ligand) superfamily, member 4 TNFSF4 7292 NM_003326 /// XM_005245475 0001816 // cytokine production // inferred from electronic annotation /// 0002215 // defense response to nematode // inferred from sequence or structural similarity /// 0002526 // acute inflammatory response // inferred from sequence or structural similarity /// 0002726 // positive regulation of T cell cytokine production // inferred from sequence or structural similarity /// 0002819 // regulation of adaptive immune response // inferred from sequence or structural similarity /// 0002830 // positive regulation of type 2 immune response // inferred from sequence or structural similarity /// 0002891 // positive regulation of immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032700 // negative regulation of interleukin-17 production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032736 // positive regulation of interleukin-13 production // inferred from sequence or structural similarity /// 0032743 // positive regulation of interleukin-2 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0035708 // interleukin-4-dependent isotype switching to IgE isotypes // inferred from electronic annotation /// 0035709 // memory T cell activation // inferred from sequence or structural similarity /// 0035712 // T-helper 2 cell activation // inferred from sequence or structural similarity /// 0035713 // response to nitrogen dioxide // inferred from sequence or structural similarity /// 0035714 // cellular response to nitrogen dioxide // inferred from electronic annotation /// 0035783 // CD4-positive, alpha-beta T cell costimulation // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0043372 // positive regulation of CD4-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045590 // negative regulation of regulatory T cell differentiation // inferred from sequence or structural similarity /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050871 // positive regulation of B cell activation // inferred from sequence or structural similarity /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from direct assay /// 0071954 // chemokine (C-C motif) ligand 11 production // inferred from sequence or structural similarity /// 1900281 // positive regulation of CD4-positive, alpha-beta T cell costimulation // inferred from sequence or structural similarity /// 2000525 // positive regulation of T cell costimulation // inferred from electronic annotation /// 2000568 // positive regulation of memory T cell activation // inferred from electronic annotation /// 2000570 // positive regulation of T-helper 2 cell activation // inferred from electronic annotation /// 2000572 // positive regulation of interleukin-4-dependent isotype switching to IgE isotypes // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from sequence or structural similarity 207427_at NM_001097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001097.1 /DEF=Homo sapiens acrosin (ACR), mRNA. /FEA=mRNA /GEN=ACR /PROD=acrosin precursor /DB_XREF=gi:4501876 /UG=Hs.183088 acrosin /FL=gb:NM_001097.1 NM_001097 acrosin ACR 49 NM_001097 0002077 // acrosome matrix dispersal // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007338 // single fertilization // inferred from sequence or structural similarity /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0007340 // acrosome reaction // inferred from mutant phenotype /// 0007340 // acrosome reaction // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from direct assay /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from electronic annotation /// 0043159 // acrosomal matrix // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004040 // amidase activity // inferred from sequence or structural similarity /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay /// 0008144 // drug binding // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042806 // fucose binding // inferred from sequence or structural similarity 207428_x_at NM_001787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001787.1 /DEF=Homo sapiens cell division cycle 2-like 1 (PITSLRE proteins) (CDC2L1), mRNA. /FEA=mRNA /GEN=CDC2L1 /PROD=cell division cycle 2-like 1 (PITSLRE proteins) /DB_XREF=gi:10835054 /UG=Hs.183418 cell division cycle 2-like 1 (PITSLRE proteins) /FL=gb:NM_001787.1 gb:AF067515.1 NM_001787 cyclin-dependent kinase 11A /// cyclin-dependent kinase 11B CDK11A /// CDK11B 984 /// 728642 NM_001291345 /// NM_001787 /// NM_024011 /// NM_033486 /// NM_033487 /// NM_033488 /// NM_033489 /// NM_033490 /// NM_033492 /// NM_033493 /// NM_033527 /// NM_033529 /// NM_033532 /// NM_033534 /// XM_006711061 /// XM_006711062 /// XM_006711063 /// XM_006711064 /// XM_006711065 /// XM_006711066 /// XM_006711067 /// XM_006711068 /// XM_006711069 /// XM_006711070 /// XM_006711071 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207429_at NM_003058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003058.1 /DEF=Homo sapiens solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), mRNA. /FEA=mRNA /GEN=SLC22A2 /PROD=solute carrier family 22 (organic cationtransporter), member 2 /DB_XREF=gi:4507000 /UG=Hs.183572 solute carrier family 22 (organic cation transporter), member 2 /FL=gb:NM_003058.1 NM_003058 solute carrier family 22 (organic cation transporter), member 2 SLC22A2 6582 NM_003058 /// NM_153191 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007589 // body fluid secretion // traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015697 // quaternary ammonium group transport // inferred from electronic annotation /// 0015871 // choline transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051608 // histamine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0008513 // secondary active organic cation transmembrane transporter activity // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 207430_s_at NM_002443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002443.1 /DEF=Homo sapiens microseminoprotein, beta- (MSMB), mRNA. /FEA=mRNA /GEN=MSMB /PROD=microseminoprotein, beta- /DB_XREF=gi:4557035 /UG=Hs.183752 microseminoprotein, beta- /FL=gb:NM_002443.1 NM_002443 microseminoprotein, beta- MSMB 4477 NM_002443 /// NM_138634 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // traceable author statement 207431_s_at NM_003676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003676.1 /DEF=Homo sapiens degenerative spermatocyte (homolog Drosophila; lipid desaturase) (DEGS), mRNA. /FEA=mRNA /GEN=DEGS /PROD=degenerative spermatocyte /DB_XREF=gi:4505192 /UG=Hs.185973 degenerative spermatocyte (homolog Drosophila; lipid desaturase) /FL=gb:AF002668.1 gb:NM_003676.1 NM_003676 delta(4)-desaturase, sphingolipid 1 DEGS1 8560 NM_003676 /// NM_144780 /// XM_006711839 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation 207432_at NM_017682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017682.1 /DEF=Homo sapiens hypothetical protein FLJ20132 (FLJ20132), mRNA. /FEA=mRNA /GEN=FLJ20132 /PROD=hypothetical protein FLJ20132 /DB_XREF=gi:8923136 /UG=Hs.190222 hypothetical protein FLJ20132 /FL=gb:NM_017682.1 NM_017682 bestrophin 2 BEST2 54831 NM_017682 /// XM_005259963 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005254 // chloride channel activity // inferred from sequence or structural similarity 207433_at NM_000572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000572.1 /DEF=Homo sapiens interleukin 10 (IL10), mRNA. /FEA=mRNA /GEN=IL10 /PROD=interleukin 10 /DB_XREF=gi:10835140 /UG=Hs.193717 interleukin 10 /FL=gb:NM_000572.1 gb:M57627.1 NM_000572 interleukin 10 IL10 3586 NM_000572 0001818 // negative regulation of cytokine production // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0002875 // negative regulation of chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002904 // positive regulation of B cell apoptotic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007253 // cytoplasmic sequestering of NF-kappaB // non-traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0014854 // response to inactivity // inferred from electronic annotation /// 0030097 // hemopoiesis // traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030595 // leukocyte chemotaxis // traceable author statement /// 0030886 // negative regulation of myeloid dendritic cell activation // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032800 // receptor biosynthetic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0042092 // type 2 immune response // traceable author statement /// 0042100 // B cell proliferation // non-traceable author statement /// 0042130 // negative regulation of T cell proliferation // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045191 // regulation of isotype switching // non-traceable author statement /// 0045347 // negative regulation of MHC class II biosynthetic process // traceable author statement /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from electronic annotation /// 0045355 // negative regulation of interferon-alpha biosynthetic process // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // non-traceable author statement /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005125 // cytokine activity // non-traceable author statement /// 0005141 // interleukin-10 receptor binding // non-traceable author statement /// 0008083 // growth factor activity // non-traceable author statement 207434_s_at NM_021603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021603.1 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 2 (FXYD2), transcript variant b, mRNA. /FEA=mRNA /GEN=FXYD2 /PROD=FXYD domain-containing ion transport regulator2, isoform 2 /DB_XREF=gi:11125763 /UG=Hs.19520 FXYD domain-containing ion transport regulator 2 /FL=gb:NM_021603.1 gb:BC005302.1 NM_021603 FXYD domain containing ion transport regulator 2 /// FXYD6-FXYD2 readthrough FXYD2 /// FXYD6-FXYD2 486 /// 100533181 NM_001127489 /// NM_001204268 /// NM_001243598 /// NM_001680 /// NM_021603 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207435_s_at NM_016333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016333.1 /DEF=Homo sapiens RNA binding protein; AT-rich element binding factor (SRM300), mRNA. /FEA=mRNA /GEN=SRM300 /PROD=splicing coactivator subunit SRm300 /DB_XREF=gi:7706718 /UG=Hs.197114 RNA binding protein; AT-rich element binding factor /FL=gb:AF201422.1 gb:NM_016333.1 NM_016333 serine/arginine repetitive matrix 2 SRRM2 23524 NM_016333 /// XM_005255225 /// XM_005255226 /// XM_005255227 /// XM_006720872 /// XM_006720873 /// XM_006720874 /// XR_243270 /// XR_243271 /// XR_429640 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from direct assay 207436_x_at NM_014896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014896.1 /DEF=Homo sapiens KIAA0894 protein (KIAA0894), mRNA. /FEA=mRNA /GEN=KIAA0894 /PROD=KIAA0894 protein /DB_XREF=gi:7662365 /UG=Hs.199117 KIAA0894 protein /FL=gb:AB020701.1 gb:NM_014896.1 NM_014896 sorbin and SH3 domain containing 1 SORBS1 10580 NM_001034954 /// NM_001034955 /// NM_001034956 /// NM_001034957 /// NM_001290294 /// NM_001290295 /// NM_001290296 /// NM_001290297 /// NM_001290298 /// NM_006434 /// NM_015385 /// NM_024991 /// XM_005269404 /// XM_005269405 /// XM_005269406 /// XM_005269411 /// XM_005269412 /// XM_005269414 /// XM_005269424 /// XM_005269425 /// XM_005269427 /// XM_005269431 /// XM_005269437 /// XM_005269439 /// XM_005269440 /// XM_006717560 /// XM_006717561 /// XM_006717562 /// XM_006717563 /// XM_006717564 /// XM_006717565 /// XM_006717566 /// XM_006717567 /// XM_006717568 /// XM_006717569 /// XM_006717570 /// XM_006717571 /// XM_006717572 /// XM_006717573 /// XM_006717574 /// XM_006717575 /// XM_006717576 /// XM_006717577 /// XM_006717578 /// XM_006717579 /// XM_006717580 /// XM_006717581 /// XM_006717582 /// XM_006717583 /// XM_006717584 /// XM_006717585 /// XM_006717586 /// XM_006717587 /// XM_006717588 /// XM_006717589 /// XM_006717590 /// XM_006717591 /// XM_006717592 /// XM_006717593 /// XM_006717594 /// XM_006717595 0006810 // transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from sequence or structural similarity /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005899 // insulin receptor complex // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from sequence or structural similarity /// 0005915 // zonula adherens // traceable author statement /// 0005924 // cell-substrate adherens junction // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0003779 // actin binding // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred by curator /// 0005070 // SH3/SH2 adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation 207437_at NM_006491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006491.1 /DEF=Homo sapiens neuro-oncological ventral antigen 1 (NOVA1), transcript variant 3, mRNA. /FEA=mRNA /GEN=NOVA1 /PROD=neuro-oncological ventral antigen 1 /DB_XREF=gi:6031188 /UG=Hs.214 neuro-oncological ventral antigen 1 /FL=gb:NM_006491.1 NM_006491 neuro-oncological ventral antigen 1 NOVA1 4857 NM_002515 /// NM_006489 /// NM_006491 /// XM_005267707 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // traceable author statement /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207438_s_at NM_005701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005701.1 /DEF=Homo sapiens RNA, U transporter 1 (RNUT1), mRNA. /FEA=mRNA /GEN=RNUT1 /PROD=RNA, U transporter 1 /DB_XREF=gi:5031832 /UG=Hs.21577 RNA, U transporter 1 /FL=gb:AF039029.1 gb:NM_005701.1 NM_005701 snurportin 1 SNUPN 10073 NM_001042581 /// NM_001042588 /// NM_005701 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0061015 // snRNA import into nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 207439_s_at NM_005660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005660.1 /DEF=Homo sapiens solute carrier family 35 (UDP-galactose transporter), member 2 (SLC35A2), mRNA. /FEA=mRNA /GEN=SLC35A2 /PROD=solute carrier family 35 (UDP-galactosetransporter), member 2 /DB_XREF=gi:5032210 /UG=Hs.21899 solute carrier family 35 (UDP-galactose transporter), member 2 /FL=gb:D88146.1 gb:NM_005660.1 NM_005660 solute carrier family 35 (UDP-galactose transporter), member A2 SLC35A2 7355 NM_001032289 /// NM_001042498 /// NM_001282647 /// NM_001282648 /// NM_001282649 /// NM_001282650 /// NM_001282651 /// NM_005660 0006012 // galactose metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015785 // UDP-galactose transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072334 // UDP-galactose transmembrane transport // inferred from electronic annotation /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005459 // UDP-galactose transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207440_at NM_005660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005660.1 /DEF=Homo sapiens solute carrier family 35 (UDP-galactose transporter), member 2 (SLC35A2), mRNA. /FEA=mRNA /GEN=SLC35A2 /PROD=solute carrier family 35 (UDP-galactosetransporter), member 2 /DB_XREF=gi:5032210 /UG=Hs.21899 solute carrier family 35 (UDP-galactose transporter), member 2 /FL=gb:D88146.1 gb:NM_005660.1 NM_005660 solute carrier family 35 (UDP-galactose transporter), member A2 SLC35A2 7355 NM_001032289 /// NM_001042498 /// NM_001282647 /// NM_001282648 /// NM_001282649 /// NM_001282650 /// NM_001282651 /// NM_005660 0006012 // galactose metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015785 // UDP-galactose transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072334 // UDP-galactose transmembrane transport // inferred from electronic annotation /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005459 // UDP-galactose transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207441_at NM_006685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006685.2 /DEF=Homo sapiens salivary proline-rich protein (P-B), mRNA. /FEA=mRNA /GEN=P-B /PROD=salivary proline-rich protein /DB_XREF=gi:6679187 /UG=Hs.2207 salivary proline-rich protein /FL=gb:D29833.2 gb:NM_006685.2 NM_006685 submaxillary gland androgen regulated protein 3B SMR3B 10879 NM_006685 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 207442_at NM_000759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000759.1 /DEF=Homo sapiens colony stimulating factor 3 (granulocyte) (CSF3), mRNA. /FEA=mRNA /GEN=CSF3 /PROD=colony stimulating factor 3 (granulocyte) /DB_XREF=gi:4503078 /UG=Hs.2233 colony stimulating factor 3 (granulocyte) /FL=gb:M17706.1 gb:NM_000759.1 NM_000759 colony stimulating factor 3 (granulocyte) CSF3 1440 NM_000759 /// NM_001178147 /// NM_172219 /// NM_172220 /// NR_033662 0006955 // immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0030851 // granulocyte differentiation // non-traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // non-traceable author statement /// 0005130 // granulocyte colony-stimulating factor receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 207443_at AF220532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220532.1 /DEF=Homo sapiens orphan nuclear receptor (NR2E1) mRNA, complete cds. /FEA=mRNA /GEN=NR2E1 /PROD=orphan nuclear receptor /DB_XREF=gi:11141398 /UG=Hs.22591 nuclear receptor subfamily 2, group E, member 1 /FL=gb:AF220532.1 gb:NM_003269.1 AF220532 nuclear receptor subfamily 2, group E, member 1 NR2E1 7101 NM_001286102 /// NM_003269 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0002118 // aggressive behavior // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021764 // amygdala development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0021872 // forebrain generation of neurons // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021960 // anterior commissure morphogenesis // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051128 // regulation of cellular component organization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0090049 // regulation of cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation /// 2000648 // positive regulation of stem cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207444_at NM_004256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004256.1 /DEF=Homo sapiens organic cationic transporter-like 3 (ORCTL3), mRNA. /FEA=mRNA /GEN=ORCTL3 /PROD=organic cation transporter like 3 /DB_XREF=gi:4758851 /UG=Hs.225941 organic cationic transporter-like 3 /FL=gb:AB010438.1 gb:NM_004256.1 NM_004256 solute carrier family 22 (organic anion/urate transporter), member 13 SLC22A13 9390 NM_004256 /// XR_245163 0015695 // organic cation transport // non-traceable author statement /// 0015747 // urate transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 2001142 // nicotinate transport // inferred from direct assay 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015101 // organic cation transmembrane transporter activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0090416 // nicotinate transporter activity // inferred from direct assay 207445_s_at AF145439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF145439.1 /DEF=Homo sapiens CC chemokine receptor 9A (CCR9) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=CCR9 /PROD=CC chemokine receptor 9A /DB_XREF=gi:7673008 /UG=Hs.225946 chemokine (C-C motif) receptor 9 /FL=gb:NM_006641.1 gb:AF145439.1 AF145439 chemokine (C-C motif) receptor 9 CCR9 10803 NM_001256369 /// NM_006641 /// NM_031200 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 207446_at NM_006068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006068.1 /DEF=Homo sapiens toll-like receptor 6 (TLR6), mRNA. /FEA=mRNA /GEN=TLR6 /PROD=toll-like receptor 6 /DB_XREF=gi:5174720 /UG=Hs.227105 toll-like receptor 6 /FL=gb:AB020807.1 gb:NM_006068.1 NM_006068 toll-like receptor 6 TLR6 10333 NM_006068 /// XM_005262636 /// XM_005262637 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0032493 // response to bacterial lipoprotein // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034150 // toll-like receptor 6 signaling pathway // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042088 // T-helper 1 type immune response // inferred by curator /// 0042496 // detection of diacyl bacterial lipopeptide // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0071726 // cellular response to diacyl bacterial lipopeptide // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035355 // Toll-like receptor 2-Toll-like receptor 6 protein complex // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042498 // diacyl lipopeptide binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071723 // lipopeptide binding // inferred from sequence or structural similarity 207447_s_at NM_013244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013244.1 /DEF=Homo sapiens UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog (HGNT-IV-H), mRNA. /FEA=mRNA /GEN=HGNT-IV-H /PROD=UDP-N-acetylglucosamine:a-1,3-D-mannosidebeta-1,4-N-acetylglucosaminyltransferase IV-homolog /DB_XREF=gi:7019406 /UG=Hs.227473 UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog /FL=gb:AB024729.1 gb:NM_013244.1 NM_013244 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) MGAT4C 25834 NM_013244 /// XM_005268776 /// XM_005268777 /// XM_005268779 /// XM_005268781 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008454 // alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207448_at NM_015227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_015227.1 /DEF=Homo sapiens KIAA0958 protein (KIAA0958), mRNA. /FEA=mRNA /GEN=KIAA0958 /PROD=OMADS1 protein /DB_XREF=gi:13273310 /UG=Hs.22982 KIAA0958 protein /FL=gb:NM_015227.1 NM_015227 protein O-fucosyltransferase 2 POFUT2 23275 NM_015227 /// NM_133634 /// NM_133635 /// NR_004858 /// XM_006723981 /// XM_006723982 /// XM_006723983 /// XM_006723984 /// XR_430348 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036066 // protein O-linked fucosylation // inferred from direct assay /// 0051046 // regulation of secretion // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046922 // peptide-O-fucosyltransferase activity // inferred from direct assay 207449_s_at NM_015227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015227.1 /DEF=Homo sapiens KIAA0958 protein (KIAA0958), mRNA. /FEA=mRNA /GEN=KIAA0958 /PROD=OMADS1 protein /DB_XREF=gi:13273310 /UG=Hs.22982 KIAA0958 protein /FL=gb:NM_015227.1 NM_015227 protein O-fucosyltransferase 2 POFUT2 23275 NM_015227 /// NM_133634 /// NM_133635 /// NR_004858 /// XM_006723981 /// XM_006723982 /// XM_006723983 /// XM_006723984 /// XR_430348 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036066 // protein O-linked fucosylation // inferred from direct assay /// 0051046 // regulation of secretion // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046922 // peptide-O-fucosyltransferase activity // inferred from direct assay 207450_s_at NM_007252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007252.1 /DEF=Homo sapiens Retina-derived POU-domain factor-1 (RPF-1), mRNA. /FEA=mRNA /GEN=RPF-1 /PROD=Retina-derived POU-domain factor-1 /DB_XREF=gi:6005855 /UG=Hs.233321 Retina-derived POU-domain factor-1 /FL=gb:U91935.1 gb:NM_007252.1 NM_007252 POU class 6 homeobox 2 POU6F2 11281 NM_001166018 /// NM_007252 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007402 // ganglion mother cell fate determination // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007601 // visual perception // traceable author statement 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207451_at NM_014360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014360.1 /DEF=Homo sapiens NK-2 (Drosophila) homolog 8 (NKX2.8), mRNA. /FEA=mRNA /GEN=NKX2.8 /PROD=NK-2 (Drosophila) homolog 8 /DB_XREF=gi:7657378 /UG=Hs.234763 NK-2 (Drosophila) homolog 8 /FL=gb:AF000295.1 gb:NM_014360.1 NM_014360 NK2 homeobox 8 NKX2-8 26257 NM_014360 0001889 // liver development // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay 207452_s_at NM_014361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014361.1 /DEF=Homo sapiens contactin 5 (CNTN5), mRNA. /FEA=mRNA /GEN=CNTN5 /PROD=contactin 5 /DB_XREF=gi:7657358 /UG=Hs.234790 contactin 5 /FL=gb:AB013802.2 gb:NM_014361.1 NM_014361 contactin 5 CNTN5 53942 NM_001243270 /// NM_001243271 /// NM_014361 /// NM_175566 0007155 // cell adhesion // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207453_s_at NM_012266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012266.1 /DEF=Homo sapiens heat shock cognate 40 (HSC40), mRNA. /FEA=mRNA /GEN=HSC40 /PROD=heat shock cognate 40 /DB_XREF=gi:6912421 /UG=Hs.237506 DnaJ (Hsp40) homolog, subfamily B, member 5 /FL=gb:AF088982.1 gb:NM_012266.1 NM_012266 DnaJ (Hsp40) homolog, subfamily B, member 5 DNAJB5 25822 NM_001135004 /// NM_001135005 /// NM_012266 /// XM_005251428 /// XM_006716751 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 207454_at NM_000831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000831.1 /DEF=Homo sapiens glutamate receptor, ionotropic, kainate 3 (GRIK3), mRNA. /FEA=mRNA /GEN=GRIK3 /PROD=glutamate receptor, ionotropic, kainate 3 /DB_XREF=gi:4504118 /UG=Hs.2389 glutamate receptor, ionotropic, kainate 3 /FL=gb:NM_000831.1 gb:U16127.1 NM_000831 glutamate receptor, ionotropic, kainate 3 GRIK3 2899 NM_000831 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from direct assay /// 0007215 // glutamate receptor signaling pathway // inferred from direct assay /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // not recorded /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0032839 // dendrite cytoplasm // inferred from sequence or structural similarity /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0001640 // adenylate cyclase inhibiting G-protein coupled glutamate receptor activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from direct assay /// 0004970 // ionotropic glutamate receptor activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // traceable author statement /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay 207455_at NM_002563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002563.1 /DEF=Homo sapiens purinergic receptor P2Y, G-protein coupled, 1 (P2RY1), mRNA. /FEA=mRNA /GEN=P2RY1 /PROD=purinergic receptor P2Y, G-protein coupled, 1 /DB_XREF=gi:4505556 /UG=Hs.2411 purinergic receptor P2Y, G-protein coupled, 1 /FL=gb:U42029.1 gb:U42030.1 gb:NM_002563.1 NM_002563 purinergic receptor P2Y, G-protein coupled, 1 P2RY1 5028 NM_002563 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043270 // positive regulation of ion transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0051100 // negative regulation of binding // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070848 // response to growth factor // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090075 // relaxation of muscle // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0031686 // A1 adenosine receptor binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from sequence or structural similarity /// 0045031 // ATP-activated nucleotide receptor activity // inferred from sequence or structural similarity /// 0045032 // ADP-activated nucleotide receptor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 207456_at NM_004133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004133.2 /DEF=Homo sapiens hepatocyte nuclear factor 4, gamma (HNF4G), mRNA. /FEA=mRNA /GEN=HNF4G /PROD=hepatocyte nuclear factor 4, gamma /DB_XREF=gi:6631087 /UG=Hs.241529 hepatocyte nuclear factor 4, gamma /FL=gb:NM_004133.2 NM_004133 hepatocyte nuclear factor 4, gamma HNF4G 3174 NM_004133 /// XM_006716446 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207457_s_at NM_021246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021246.1 /DEF=Homo sapiens megakaryocyte-enhanced gene transcript 1 protein (MEGT1), mRNA. /FEA=mRNA /GEN=MEGT1 /PROD=megakaryocyte-enhanced gene transcript 1protein /DB_XREF=gi:10864054 /UG=Hs.241587 megakaryocyte-enhanced gene transcript 1 protein /FL=gb:NM_021246.1 gb:AF195764.1 NM_021246 lymphocyte antigen 6 complex, locus G6D /// lymphocyte antigen 6 complex, locus G6F LY6G6D /// LY6G6F 58530 /// 259215 NM_001003693 /// NM_021246 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207458_at NM_024035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024035.1 /DEF=Homo sapiens hypothetical protein MGC3113 (MGC3113), mRNA. /FEA=mRNA /GEN=MGC3113 /PROD=hypothetical protein MGC3113 /DB_XREF=gi:13128985 /UG=Hs.245886 hypothetical protein MGC3113 /FL=gb:BC000203.1 gb:NM_024035.1 NM_024035 RHPN1 antisense RNA 1 (head to head) RHPN1-AS1 78998 NM_024035 /// NR_026785 207459_x_at NM_002100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002100.2 /DEF=Homo sapiens glycophorin B (includes Ss blood group) (GYPB), mRNA. /FEA=mRNA /GEN=GYPB /PROD=glycophorin B precursor /DB_XREF=gi:8051603 /UG=Hs.250653 glycophorin B (includes Ss blood group) /FL=gb:J02982.1 gb:NM_002100.2 NM_002100 glycophorin B (MNS blood group) GYPB 2994 NM_002100 /// XM_005262968 /// XM_005262969 /// XM_005262970 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 207460_at NM_005317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005317.2 /DEF=Homo sapiens granzyme M (lymphocyte met-ase 1) (GZMM), mRNA. /FEA=mRNA /GEN=GZMM /PROD=granzyme M precursor /DB_XREF=gi:7108347 /UG=Hs.268531 granzyme M (lymphocyte met-ase 1) /FL=gb:L23134.1 gb:NM_005317.2 NM_005317 granzyme M (lymphocyte met-ase 1) GZMM 3004 NM_001258351 /// NM_005317 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207461_at NM_001272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001272.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 3 (CHD3), mRNA. /FEA=mRNA /GEN=CHD3 /PROD=chromodomain helicase DNA binding protein 3 /DB_XREF=gi:4557450 /UG=Hs.25601 chromodomain helicase DNA binding protein 3 /FL=gb:AF006515.1 gb:NM_001272.1 NM_001272 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007051 // spindle organization // inferred from direct assay /// 0007051 // spindle organization // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0051297 // centrosome organization // inferred from direct assay /// 0051297 // centrosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207462_at NM_002063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002063.1 /DEF=Homo sapiens glycine receptor, alpha 2 (GLRA2), mRNA. /FEA=mRNA /GEN=GLRA2 /PROD=glycine receptor, alpha 2 /DB_XREF=gi:4504020 /UG=Hs.2700 glycine receptor, alpha 2 /FL=gb:NM_002063.1 NM_002063 glycine receptor, alpha 2 GLRA2 2742 NM_001118885 /// NM_001118886 /// NM_001171942 /// NM_002063 /// XM_006724487 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007416 // synapse assembly // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from direct assay /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from direct assay /// 0022824 // transmitter-gated ion channel activity // inferred from electronic annotation 207463_x_at NM_002771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002771.1 /DEF=Homo sapiens protease, serine, 3 (trypsin 3) (PRSS3), mRNA. /FEA=mRNA /GEN=PRSS3 /PROD=protease, serine, 3 (trypsin 3) /DB_XREF=gi:4506148 /UG=Hs.278310 protease, serine, 3 (trypsin 3) /FL=gb:NM_002771.1 NM_002771 protease, serine, 3 PRSS3 5646 NM_001197097 /// NM_001197098 /// NM_002771 /// NM_007343 /// XM_005251519 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // traceable author statement /// 0009235 // cobalamin metabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207464_at NM_014121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014121.1 /DEF=Homo sapiens PRO0233 protein (PRO0233), mRNA. /FEA=mRNA /GEN=PRO0233 /PROD=PRO0233 protein /DB_XREF=gi:7662535 /UG=Hs.278933 PRO0233 protein /FL=gb:AF090905.1 gb:NM_014121.1 NM_014121 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 207465_at NM_014134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014134.1 /DEF=Homo sapiens PRO0628 protein (PRO0628), mRNA. /FEA=mRNA /GEN=PRO0628 /PROD=PRO0628 protein /DB_XREF=gi:7662575 /UG=Hs.278941 PRO0628 protein /FL=gb:AF090938.1 gb:NM_014134.1 NM_014134 uncharacterized LOC100127886 LOC100127886 100127886 XM_001721143 /// XM_001721647 207466_at NM_015973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015973.1 /DEF=Homo sapiens galanin-related peptide (LOC51083), mRNA. /FEA=mRNA /GEN=LOC51083 /PROD=galanin-related peptide /DB_XREF=gi:7705741 /UG=Hs.278959 galanin-related peptide /FL=gb:AF077047.1 gb:NM_015973.1 NM_015973 galanin/GMAP prepropeptide GAL 51083 NM_015973 /// XM_006718580 0006954 // inflammatory response // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010737 // protein kinase A signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030073 // insulin secretion // non-traceable author statement /// 0031943 // regulation of glucocorticoid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0051464 // positive regulation of cortisol secretion // inferred from direct assay /// 0051795 // positive regulation of catagen // inferred from direct assay /// 1902608 // positive regulation of large conductance calcium-activated potassium channel activity // inferred from direct assay /// 1902891 // negative regulation of root hair elongation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031764 // type 1 galanin receptor binding // inferred from direct assay /// 0031765 // type 2 galanin receptor binding // inferred from direct assay /// 0031766 // type 3 galanin receptor binding // inferred from direct assay 207467_x_at NM_001750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001750.2 /DEF=Homo sapiens calpastatin (CAST), mRNA. /FEA=mRNA /GEN=CAST /PROD=calpastatin /DB_XREF=gi:5729759 /UG=Hs.279607 calpastatin /FL=gb:U58996.2 gb:NM_001750.2 NM_001750 calpastatin CAST 831 NM_001042440 /// NM_001042441 /// NM_001042442 /// NM_001042443 /// NM_001042444 /// NM_001042445 /// NM_001042446 /// NM_001190442 /// NM_001284212 /// NM_001284213 /// NM_001750 /// NM_173060 /// NM_173061 /// NM_173062 /// NM_173063 /// NR_033798 /// NR_104285 /// XM_006714696 /// XM_006714697 /// XM_006714698 /// XM_006714699 /// XM_006714700 /// XM_006714701 /// XM_006714702 /// XM_006714703 /// XM_006714704 /// XM_006714705 /// XM_006714706 /// XM_006714707 /// XM_006714708 /// XM_006714709 /// XM_006714710 /// XM_006714711 /// XM_006714712 /// XM_006714713 /// XM_006714714 /// XM_006714715 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010859 // calcium-dependent cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207468_s_at NM_003015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003015.2 /DEF=Homo sapiens secreted frizzled-related protein 5 (SFRP5), mRNA. /FEA=mRNA /GEN=SFRP5 /PROD=secreted frizzled-related protein 5 /DB_XREF=gi:8400734 /UG=Hs.279565 secreted frizzled-related protein 5 /FL=gb:AF017988.1 gb:NM_003015.2 NM_003015 secreted frizzled-related protein 5 SFRP5 6425 NM_003015 0001944 // vasculature development // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0007601 // visual perception // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008406 // gonad development // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060028 // convergent extension involved in axis elongation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000057 // negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0042995 // cell projection // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 207469_s_at NM_003662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003662.1 /DEF=Homo sapiens Pirin (PIR), mRNA. /FEA=mRNA /GEN=PIR /PROD=pirin /DB_XREF=gi:4505822 /UG=Hs.279663 Pirin /FL=gb:NM_003662.1 NM_003662 pirin (iron-binding nuclear protein) PIR 8544 NM_001018109 /// NM_003662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003712 // transcription cofactor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008127 // quercetin 2,3-dioxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation 207470_at NM_017535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017535.1 /DEF=Homo sapiens hypothetical protein DKFZp566H0824 (DKFZp566H0824), mRNA. /FEA=mRNA /GEN=DKFZp566H0824 /PROD=hypothetical protein DKFZp566H0824 /DB_XREF=gi:8922158 /UG=Hs.279803 hypothetical protein DKFZp566H0824 /FL=gb:NM_017535.1 NM_017535 Homo sapiens hypothetical LOC54744, mRNA (cDNA clone IMAGE:4607730), with apparent retained intron. BC113958 207471_at AF118086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF118086.1 /DEF=Homo sapiens PRO1992 mRNA, complete cds. /FEA=mRNA /PROD=PRO1992 /DB_XREF=gi:6650817 /UG=Hs.279839 PRO1992 protein /FL=gb:AF118086.1 gb:NM_014107.1 AF118086 207472_at NM_014107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014107.1 /DEF=Homo sapiens PRO1992 protein (PRO1992), mRNA. /FEA=mRNA /GEN=PRO1992 /PROD=PRO1992 protein /DB_XREF=gi:7662626 /UG=Hs.279839 PRO1992 protein /FL=gb:AF118086.1 gb:NM_014107.1 NM_014107 arginyl-tRNA synthetase 2, mitochondrial RARS2 57038 NM_020320 /// XM_005248735 /// XM_005248736 /// XM_005248737 /// XR_241848 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207473_at NM_002418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002418.1 /DEF=Homo sapiens motilin (MLN), mRNA. /FEA=mRNA /GEN=MLN /PROD=motilin /DB_XREF=gi:4557033 /UG=Hs.2813 motilin /FL=gb:NM_002418.1 NM_002418 motilin MLN 4295 NM_001040109 /// NM_001184698 /// NM_002418 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 207474_at NM_017719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017719.1 /DEF=Homo sapiens hypothetical protein FLJ20224 (FLJ20224), mRNA. /FEA=mRNA /GEN=FLJ20224 /PROD=hypothetical protein FLJ20224 /DB_XREF=gi:8923211 /UG=Hs.279846 hypothetical protein FLJ20224 /FL=gb:NM_017719.1 NM_017719 SNF related kinase SNRK 54861 NM_001100594 /// NM_017719 /// XM_005265245 /// XM_005265246 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207475_at NM_000134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000134.2 /DEF=Homo sapiens fatty acid binding protein 2, intestinal (FABP2), mRNA. /FEA=mRNA /GEN=FABP2 /PROD=intestinal fatty acid binding protein 2 /DB_XREF=gi:10938019 /UG=Hs.282265 fatty acid binding protein 2, intestinal /FL=gb:NM_000134.2 NM_000134 fatty acid binding protein 2, intestinal FABP2 2169 NM_000134 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0050892 // intestinal absorption // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0045179 // apical cortex // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005324 // long-chain fatty acid transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 207476_at NM_018512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018512.1 /DEF=Homo sapiens hypothetical protein PRO2015 (PRO2015), mRNA. /FEA=mRNA /GEN=PRO2015 /PROD=hypothetical protein PRO2015 /DB_XREF=gi:8924109 /UG=Hs.283032 hypothetical protein PRO2015 /FL=gb:AF119861.1 gb:NM_018512.1 NM_018512 uncharacterized LOC100507630 LOC100507630 100507630 XR_132706 /// XR_133297 /// XR_171283 207477_at AF119909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF119909.1 /DEF=Homo sapiens PRO2958 mRNA, complete cds. /FEA=mRNA /PROD=PRO2958 /DB_XREF=gi:7770254 /UG=Hs.283046 hypothetical protein PRO2958 /FL=gb:AF119909.1 gb:NM_018546.1 AF119909 207478_at NM_018546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018546.1 /DEF=Homo sapiens hypothetical protein PRO2958 (PRO2958), mRNA. /FEA=mRNA /GEN=PRO2958 /PROD=hypothetical protein PRO2958 /DB_XREF=gi:8924222 /UG=Hs.283046 hypothetical protein PRO2958 /FL=gb:AF119909.1 gb:NM_018546.1 NM_018546 uncharacterized LOC100128329 PRO2958 100128329 XM_001720404 /// XM_001722263 207479_at NM_018613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018613.1 /DEF=Homo sapiens hypothetical protein PRO2007 (PRO2007), mRNA. /FEA=mRNA /GEN=PRO2007 /PROD=hypothetical protein PRO2007 /DB_XREF=gi:8924105 /UG=Hs.283065 hypothetical protein PRO2007 /FL=gb:AF116680.1 gb:NM_018613.1 NM_018613 207480_s_at NM_020149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020149.1 /DEF=Homo sapiens TALE homeobox protein Meis2e (LOC56908), mRNA. /FEA=mRNA /GEN=LOC56908 /PROD=TALE homeobox protein Meis2e /DB_XREF=gi:9910355 /UG=Hs.283312 TALE homeobox protein Meis2e /FL=gb:AF179899.1 gb:NM_020149.1 NM_020149 Meis homeobox 2 MEIS2 4212 NM_001220482 /// NM_002399 /// NM_020149 /// NM_170674 /// NM_170675 /// NM_170676 /// NM_170677 /// NM_172315 /// NM_172316 /// NR_051953 /// XM_006720522 /// XM_006720523 /// XM_006720524 /// XM_006720525 /// XM_006720526 /// XM_006720527 /// XM_006720528 /// XM_006720529 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001654 // eye development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0070848 // response to growth factor // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay 207481_at NM_018541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018541.1 /DEF=Homo sapiens hypothetical protein PRO2832 (PRO2832), mRNA. /FEA=mRNA /GEN=PRO2832 /PROD=hypothetical protein PRO2832 /DB_XREF=gi:8924207 /UG=Hs.283319 hypothetical protein PRO2832 /FL=gb:AF119902.1 gb:NM_018541.1 NM_018541 207482_at NM_014477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014477.1 /DEF=Homo sapiens clg01 protein (CLG01), mRNA. /FEA=mRNA /GEN=CLG01 /PROD=clg01 protein /DB_XREF=gi:7656982 /UG=Hs.283640 clg01 protein /FL=gb:AB017802.1 gb:NM_014477.1 NM_014477 TP53 target 5 TP53TG5 27296 NM_014477 /// XM_006723777 /// XM_006723778 /// XM_006723779 /// XM_006723780 0030308 // negative regulation of cell growth // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 207483_s_at NM_018448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018448.1 /DEF=Homo sapiens TIP120 protein (TIP120), mRNA. /FEA=mRNA /GEN=TIP120 /PROD=TIP120 protein /DB_XREF=gi:8924259 /UG=Hs.283668 TIP120 protein /FL=gb:AF157326.1 gb:NM_018448.1 NM_018448 cullin-associated and neddylation-dissociated 1 CAND1 55832 NM_018448 0010265 // SCF complex assembly // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from electronic annotation 207484_s_at NM_025256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025256.1 /DEF=Homo sapiens NG36 protein (NG36), mRNA. /FEA=mRNA /GEN=NG36 /PROD=NG36 protein /DB_XREF=gi:13376865 /UG=Hs.283874 NG36 protein /FL=gb:NM_025256.1 NM_025256 euchromatic histone-lysine N-methyltransferase 2 EHMT2 10919 NM_001289413 /// NM_006709 /// NM_025256 /// XM_005248824 /// XM_005272767 /// XM_005274833 /// XM_005274835 /// XM_005274913 /// XM_005275207 /// XM_005275209 /// XM_005275343 /// XM_005275345 /// XM_006714974 /// XM_006714975 /// XM_006714976 /// XM_006725028 /// XM_006725029 /// XM_006725467 /// XM_006725468 /// XM_006725469 /// XM_006725682 /// XM_006725683 /// XM_006725684 /// XM_006725892 /// XM_006725893 /// XM_006725981 /// XM_006725982 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from mutant phenotype /// 0018027 // peptidyl-lysine dimethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from sequence or structural similarity /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from sequence or structural similarity /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 207485_x_at NM_007048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007048.1 /DEF=Homo sapiens butyrophilin, subfamily 3, member A1 (BTN3A1), mRNA. /FEA=mRNA /GEN=BTN3A1 /PROD=butyrophilin, subfamily 3, member A1 /DB_XREF=gi:5901903 /UG=Hs.284283 butyrophilin, subfamily 3, member A1 /FL=gb:NM_007048.1 NM_007048 butyrophilin, subfamily 3, member A1 BTN3A1 11119 NM_001145008 /// NM_001145009 /// NM_007048 /// NM_194441 /// XM_005248833 /// XM_005248834 /// XM_006714983 0002376 // immune system process // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from direct assay /// 0050798 // activated T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207486_x_at NM_004067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004067.1 /DEF=Homo sapiens chimerin (chimaerin) 2 (CHN2), mRNA. /FEA=mRNA /GEN=CHN2 /PROD=chimerin (chimaerin) 2 /DB_XREF=gi:4757979 /UG=Hs.286055 chimerin (chimaerin) 2 /FL=gb:NM_004067.1 gb:U28926.1 NM_004067 chimerin 2 CHN2 1124 NM_001039936 /// NM_001293069 /// NM_001293070 /// NM_001293071 /// NM_001293072 /// NM_001293073 /// NM_001293075 /// NM_001293076 /// NM_001293077 /// NM_001293078 /// NM_001293079 /// NM_001293080 /// NM_001293081 /// NM_004067 /// NR_120524 /// NR_120525 /// XM_005249599 /// XM_005249602 /// XR_171041 /// XR_171649 /// XR_172478 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207487_at NM_024976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024976.1 /DEF=Homo sapiens hypothetical protein FLJ11996 (FLJ11996), mRNA. /FEA=mRNA /GEN=FLJ11996 /PROD=hypothetical protein FLJ11996 /DB_XREF=gi:13376475 /UG=Hs.287473 hypothetical protein FLJ11996 /FL=gb:NM_024976.1 NM_024976 207488_at NM_024999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024999.1 /DEF=Homo sapiens hypothetical protein FLJ12988 (FLJ12988), mRNA. /FEA=mRNA /GEN=FLJ12988 /PROD=hypothetical protein FLJ12988 /DB_XREF=gi:13430875 /UG=Hs.287545 hypothetical protein FLJ12988 /FL=gb:NM_024999.1 NM_024999 207489_at NM_024986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024986.1 /DEF=Homo sapiens hypothetical protein FLJ12331 (FLJ12331), mRNA. /FEA=mRNA /GEN=FLJ12331 /PROD=hypothetical protein FLJ12331 /DB_XREF=gi:13376487 /UG=Hs.287515 hypothetical protein FLJ12331 /FL=gb:NM_024986.1 NM_024986 ribosomal protein S2 pseudogene 45 /// RPS2P45 /// RPS2P45 80052 NM_024986 0006412 // translation // inferred from electronic annotation 0005840 // ribosome // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 207490_at NM_025019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025019.1 /DEF=Homo sapiens hypothetical protein FLJ13940 (FLJ13940), mRNA. /FEA=mRNA /GEN=FLJ13940 /PROD=hypothetical protein FLJ13940 /DB_XREF=gi:13376538 /UG=Hs.287610 hypothetical protein FLJ13940 /FL=gb:NM_025019.1 NM_025019 tubulin, alpha 4b (pseudogene) TUBA4B 80086 NR_003063 0007017 // microtubule-based process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 207491_at NM_025098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025098.1 /DEF=Homo sapiens hypothetical protein FLJ22644 (FLJ22644), mRNA. /FEA=mRNA /GEN=FLJ22644 /PROD=hypothetical protein FLJ22644 /DB_XREF=gi:13376661 /UG=Hs.288568 hypothetical protein FLJ22644 /FL=gb:NM_025098.1 NM_025098 monoacylglycerol O-acyltransferase 2 MOGAT2 80168 NM_025098 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006651 // diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0050892 // intestinal absorption // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003846 // 2-acylglycerol O-acyltransferase activity // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 207492_at NM_025105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025105.1 /DEF=Homo sapiens hypothetical protein FLJ12409 (FLJ12409), mRNA. /FEA=mRNA /GEN=FLJ12409 /PROD=hypothetical protein FLJ12409 /DB_XREF=gi:13376672 /UG=Hs.288640 hypothetical protein FLJ12409 /FL=gb:NM_025105.1 NM_025105 N-glycanase 1 NGLY1 55768 NM_001145293 /// NM_001145294 /// NM_001145295 /// NM_018297 /// NM_025105 /// XM_005265316 /// XM_005265317 0006516 // glycoprotein catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0000224 // peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207493_x_at NM_003147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003147.1 /DEF=Homo sapiens synovial sarcoma, X breakpoint 2 (SSX2), mRNA. /FEA=mRNA /GEN=SSX2 /PROD=synovial sarcoma, X breakpoint 2 /DB_XREF=gi:10337582 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 /FL=gb:NM_003147.1 NM_003147 synovial sarcoma, X breakpoint 2 /// synovial sarcoma, X breakpoint 2B SSX2 /// SSX2B 6757 /// 727837 NM_001164417 /// NM_001278697 /// NM_001278701 /// NM_001278702 /// NM_003147 /// NM_175698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207494_s_at NM_003427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003427.1 /DEF=Homo sapiens zinc finger protein 76 (expressed in testis) (ZNF76), mRNA. /FEA=mRNA /GEN=ZNF76 /PROD=zinc finger protein 76 (expressed in testis) /DB_XREF=gi:4508032 /UG=Hs.29222 zinc finger protein 76 (expressed in testis) /FL=gb:NM_003427.1 NM_003427 zinc finger protein 76 ZNF76 7629 NM_001292032 /// NM_003427 /// XM_005249364 /// XM_005249369 /// XM_005249370 /// XR_241915 /// XR_241916 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207495_at NM_004249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004249.1 /DEF=Homo sapiens RAB28, member RAS oncogene family (RAB28), mRNA. /FEA=mRNA /GEN=RAB28 /PROD=RAB28, member RAS oncogene family /DB_XREF=gi:4758993 /UG=Hs.296371 RAB28, member RAS oncogene family /FL=gb:NM_004249.1 NM_004249 RAB28, member RAS oncogene family RAB28 9364 NM_001017979 /// NM_001159601 /// NM_004249 /// XM_005248215 /// XM_005248217 /// XM_005248218 /// XM_006713987 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 207496_at NM_000139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000139.1 /DEF=Homo sapiens membrane-spanning 4-domains, subfamily A, member 1 (MS4A1), mRNA. /FEA=mRNA /GEN=MS4A1 /PROD=membrane-spanning 4-domains, subfamily A, member1 /DB_XREF=gi:4503676 /UG=Hs.30 membrane-spanning 4-domains, subfamily A, member 1 /FL=gb:D10583.1 gb:NM_000139.1 NM_000139 membrane-spanning 4-domains, subfamily A, member 2 MS4A2 2206 NM_000139 /// NM_001142303 /// NM_001256916 /// XM_005273846 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032998 // Fc-epsilon receptor I complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0019863 // IgE binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 207497_s_at D10583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D10583.1 /DEF=Homo sapiens mRNA for IgE receptor beta subunit, complete cds. /FEA=mRNA /PROD=IgE receptor beta subunit /DB_XREF=gi:219881 /UG=Hs.30 membrane-spanning 4-domains, subfamily A, member 1 /FL=gb:D10583.1 gb:NM_000139.1 D10583 membrane-spanning 4-domains, subfamily A, member 2 MS4A2 2206 NM_000139 /// NM_001142303 /// NM_001256916 /// XM_005273846 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0006959 // humoral immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032998 // Fc-epsilon receptor I complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005262 // calcium channel activity // traceable author statement /// 0019863 // IgE binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 207498_s_at NM_000106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000106.1 /DEF=Homo sapiens cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 (CYP2D6), mRNA. /FEA=mRNA /GEN=CYP2D6 /PROD=cytochrome P450, subfamily IID (debrisoquine,sparteine, etc., -metabolizing), polypeptide 6 /DB_XREF=gi:4503222 /UG=Hs.301086 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 /FL=gb:M20403.1 gb:NM_000106.1 NM_000106 cytochrome P450, family 2, subfamily D, polypeptide 6 /// cytochrome P450, family 2, subfamily D, polypeptide 7, pseudogene /// cytochrome P450, family 2, subfamily D, polypeptide 6 pseudogene CYP2D6 /// CYP2D7P /// LOC101929829 1564 /// 1565 /// 101929829 NM_000106 /// NM_001025161 /// NR_002570 /// NR_111920 /// XM_005278354 /// XM_005278357 /// XM_006724157 /// XM_006726317 /// XM_006726320 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0009820 // alkaloid metabolic process // inferred from direct assay /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0033076 // isoquinoline alkaloid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0051100 // negative regulation of binding // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0090350 // negative regulation of cellular organofluorine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207499_x_at NM_017979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017979.1 /DEF=Homo sapiens hypothetical protein FLJ10043 (FLJ10043), mRNA. /FEA=mRNA /GEN=FLJ10043 /PROD=hypothetical protein FLJ10043 /DB_XREF=gi:8922201 /UG=Hs.306205 hypothetical protein FLJ10043 /FL=gb:NM_017979.1 NM_017979 unc-45 homolog A (C. elegans) UNC45A 55898 NM_001039675 /// NM_017979 /// NM_018671 /// XM_005254963 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0051879 // Hsp90 protein binding // inferred from electronic annotation 207500_at NM_004347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004347.1 /DEF=Homo sapiens caspase 5, apoptosis-related cysteine protease (CASP5), mRNA. /FEA=mRNA /GEN=CASP5 /PROD=caspase 5, apoptosis-related cysteine protease /DB_XREF=gi:4757913 /UG=Hs.3257 caspase 5, apoptosis-related cysteine protease /FL=gb:NM_004347.1 gb:U28015.1 NM_004347 caspase 5, apoptosis-related cysteine peptidase CASP5 838 NM_001136109 /// NM_001136110 /// NM_001136112 /// NM_004347 /// NR_024239 /// NR_036562 /// XM_006718925 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097194 // execution phase of apoptosis // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0072557 // IPAF inflammasome complex // not recorded /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // not recorded /// 0097169 // AIM2 inflammasome complex // not recorded 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207501_s_at NM_004113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004113.2 /DEF=Homo sapiens fibroblast growth factor 12B (FGF12B), mRNA. /FEA=mRNA /GEN=FGF12B /PROD=fibroblast growth factor 12B /DB_XREF=gi:5729823 /UG=Hs.326401 fibroblast growth factor 12B /FL=gb:U76381.2 gb:NM_004113.2 NM_004113 fibroblast growth factor 12 FGF12 2257 NM_004113 /// NM_021032 /// XM_005247227 /// XM_006713538 /// XM_006713539 0003254 // regulation of membrane depolarization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // inferred from physical interaction /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0086002 // cardiac muscle cell action potential involved in contraction // non-traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred from sequence or structural similarity /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001258 // negative regulation of cation channel activity // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity 207502_at NM_007102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007102.1 /DEF=Homo sapiens guanylate cyclase activator 2B (uroguanylin) (GUCA2B), mRNA. /FEA=mRNA /GEN=GUCA2B /PROD=guanylate cyclase activator 2B (uroguanylin) /DB_XREF=gi:6005773 /UG=Hs.32966 guanylate cyclase activator 2B (uroguanylin) /FL=gb:U34279.1 gb:NM_007102.1 NM_007102 guanylate cyclase activator 2B (uroguanylin) GUCA2B 2981 NM_007102 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030802 // regulation of cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // traceable author statement 207503_at NM_004610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004610.1 /DEF=Homo sapiens t-complex 10 (a murine tcp homolog) (TCP10), mRNA. /FEA=mRNA /GEN=TCP10 /PROD=t-complex 10 (a murine tcp homolog) /DB_XREF=gi:4759221 /UG=Hs.351 t-complex 10 (a murine tcp homolog) /FL=gb:U03399.1 gb:NM_004610.1 NM_004610 t-complex 10 TCP10 6953 NM_004610 0005829 // cytosol // traceable author statement 207504_at NM_005182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005182.1 /DEF=Homo sapiens carbonic anhydrase VII (CA7), mRNA. /FEA=mRNA /GEN=CA7 /PROD=carbonic anhydrase VII /DB_XREF=gi:4885100 /UG=Hs.37014 carbonic anhydrase VII /FL=gb:NM_005182.1 NM_005182 carbonic anhydrase VII CA7 766 NM_001014435 /// NM_005182 /// XM_005256135 /// XM_005256136 /// XM_006721267 /// XM_006721268 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207505_at NM_006259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006259.1 /DEF=Homo sapiens protein kinase, cGMP-dependent, type II (PRKG2), mRNA. /FEA=mRNA /GEN=PRKG2 /PROD=protein kinase, cGMP-dependent, type II /DB_XREF=gi:5453977 /UG=Hs.41749 protein kinase, cGMP-dependent, type II /FL=gb:D70899.1 gb:NM_006259.1 NM_006259 protein kinase, cGMP-dependent, type II PRKG2 5593 NM_001282480 /// NM_001282481 /// NM_001282482 /// NM_001282483 /// NM_001282485 /// NM_006259 /// XM_005263126 /// XM_006714266 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004692 // cGMP-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation 207506_at NM_006541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006541.1 /DEF=Homo sapiens thioredoxin-like (TXNL2), mRNA. /FEA=mRNA /GEN=TXNL2 /PROD=thioredoxin-like /DB_XREF=gi:5730103 /UG=Hs.42644 thioredoxin-like /FL=gb:NM_006541.1 NM_006541 glutaredoxin 3 GLRX3 10539 NM_001199868 /// NM_006541 /// XM_005252657 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 207507_s_at NM_001689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001689.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 (ATP5G3), mRNA. /FEA=mRNA /GEN=ATP5G3 /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit c (subunit 9) isoform 3 /DB_XREF=gi:4502300 /UG=Hs.429 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 /FL=gb:U09813.1 gb:NM_001689.1 NM_001689 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) ATP5G3 518 NM_001002258 /// NM_001190329 /// NM_001689 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 207508_at NM_001689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001689.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 (ATP5G3), mRNA. /FEA=mRNA /GEN=ATP5G3 /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit c (subunit 9) isoform 3 /DB_XREF=gi:4502300 /UG=Hs.429 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 /FL=gb:U09813.1 gb:NM_001689.1 NM_001689 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) ATP5G3 518 NM_001002258 /// NM_001190329 /// NM_001689 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 207509_s_at NM_002288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002288.2 /DEF=Homo sapiens leukocyte-associated Ig-like receptor 2 (LAIR2), transcript variant 1, mRNA. /FEA=mRNA /GEN=LAIR2 /PROD=leukocyte-associated Ig-like receptor 2, isoforma /DB_XREF=gi:10947100 /UG=Hs.43803 leukocyte-associated Ig-like receptor 2 /FL=gb:NM_002288.2 NM_002288 leukocyte-associated immunoglobulin-like receptor 2 LAIR2 3904 NM_002288 /// NM_021270 /// XM_005277264 0005576 // extracellular region // inferred from electronic annotation 207510_at NM_000710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000710.1 /DEF=Homo sapiens bradykinin receptor B1 (BDKRB1), mRNA. /FEA=mRNA /GEN=BDKRB1 /PROD=bradykinin receptor B1 /DB_XREF=gi:4502390 /UG=Hs.46348 bradykinin receptor B1 /FL=gb:NM_000710.1 gb:U12512.1 NM_000710 bradykinin receptor B1 BDKRB1 623 NM_000710 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004947 // bradykinin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 207511_s_at NM_015680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015680.1 /DEF=Homo sapiens hypothetical protein (CGI-57), mRNA. /FEA=mRNA /GEN=CGI-57 /PROD=hypothetical protein /DB_XREF=gi:7661543 /UG=Hs.4973 hypothetical protein /FL=gb:AF151815.1 gb:NM_015680.1 NM_015680 cyclin Pas1/PHO80 domain containing 1 CNPPD1 27013 NM_015680 /// XM_005246462 /// XM_005246463 /// XM_006712419 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019901 // protein kinase binding // inferred from electronic annotation 207513_s_at NM_003452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003452.1 /DEF=Homo sapiens zinc finger protein 189 (ZNF189), mRNA. /FEA=mRNA /GEN=ZNF189 /PROD=zinc finger protein 189 /DB_XREF=gi:10835038 /UG=Hs.50123 zinc finger protein 189 /FL=gb:NM_003452.1 gb:U75454.1 NM_003452 zinc finger protein 189 ZNF189 7743 NM_001278231 /// NM_001278232 /// NM_001278240 /// NM_003452 /// NM_197977 /// NR_103480 /// XM_006717280 /// XM_006717281 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207514_s_at NM_000172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000172.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), mRNA. /FEA=mRNA /GEN=GNAT1 /PROD=guanine nucleotide binding protein (G protein),alpha transducing activity polypeptide 1 /DB_XREF=gi:4504048 /UG=Hs.51147 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 /FL=gb:NM_000172.1 NM_000172 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 GNAT1 2779 NM_000172 /// NM_144499 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // inferred from mutant phenotype /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009642 // response to light intensity // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0050917 // sensory perception of umami taste // not recorded /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000035 // acyl binding // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207515_s_at NM_004875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004875.1 /DEF=Homo sapiens RNA polymerase I subunit (RPA40), mRNA. /FEA=mRNA /GEN=RPA40 /PROD=RNA polymerase I subunit /DB_XREF=gi:4759045 /UG=Hs.5409 RNA polymerase I subunit /FL=gb:AF047441.1 gb:NM_004875.1 NM_004875 polymerase (RNA) I polypeptide C, 30kDa POLR1C 9533 NM_004875 /// NM_203290 /// XM_005249491 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // traceable author statement /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 207516_at NM_000750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000750.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 4 (CHRNB4), mRNA. /FEA=mRNA /GEN=CHRNB4 /PROD=cholinergic receptor, nicotinic, betapolypeptide 4 /DB_XREF=gi:4502836 /UG=Hs.54397 cholinergic receptor, nicotinic, beta polypeptide 4 /FL=gb:U48861.1 gb:U62439.1 gb:NM_000750.1 NM_000750 cholinergic receptor, nicotinic, beta 4 (neuronal) CHRNB4 1143 NM_000750 /// NM_001256567 0001508 // action potential // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035095 // behavioral response to nicotine // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // non-traceable author statement /// 0060084 // synaptic transmission involved in micturition // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0005892 // acetylcholine-gated channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay 207517_at NM_018891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018891.1 /DEF=Homo sapiens laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) (LAMC2), transcript variant 2, mRNA. /FEA=mRNA /GEN=LAMC2 /PROD=laminin, gamma 2 isoform b precursor /DB_XREF=gi:9845499 /UG=Hs.54451 laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) /FL=gb:NM_018891.1 NM_018891 laminin, gamma 2 LAMC2 3918 NM_005562 /// NM_018891 /// XM_005245150 /// XM_006711316 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005607 // laminin-2 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 207518_at NM_003647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003647.1 /DEF=Homo sapiens diacylglycerol kinase, epsilon (64kD) (DGKE), mRNA. /FEA=mRNA /GEN=DGKE /PROD=diacylglycerol kinase epsilon /DB_XREF=gi:4503312 /UG=Hs.54506 diacylglycerol kinase, epsilon (64kD) /FL=gb:U49379.1 gb:NM_003647.1 NM_003647 diacylglycerol kinase, epsilon 64kDa DGKE 8526 NM_003647 /// XM_005257749 /// XM_006722143 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207519_at NM_001045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001045.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), mRNA. /FEA=mRNA /GEN=SLC6A4 /PROD=solute carrier family 6 (neurotransmittertransporter, serotonin), member 4 /DB_XREF=gi:4507042 /UG=Hs.553 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 /FL=gb:L05568.1 gb:NM_001045.1 NM_001045 solute carrier family 6 (neurotransmitter transporter), member 4 SLC6A4 6532 NM_001045 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006837 // serotonin transport // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0015844 // monoamine transport // inferred from direct assay /// 0021794 // thalamus development // inferred from mutant phenotype /// 0021941 // negative regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0032227 // negative regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051610 // serotonin uptake // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071321 // cellular response to cGMP // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred by curator /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005335 // serotonin:sodium symporter activity // inferred from direct assay /// 0005335 // serotonin:sodium symporter activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015222 // serotonin transmembrane transporter activity // inferred from direct assay /// 0015222 // serotonin transmembrane transporter activity // inferred from mutant phenotype /// 0015293 // symporter activity // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019811 // cocaine binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity 207520_at BG494940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG494940 /FEA=EST /DB_XREF=gi:13456455 /DB_XREF=est:602540961F1 /CLONE=IMAGE:4671854 /UG=Hs.554 Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) /FL=gb:J04137.1 gb:NM_004600.1 BG494940 TROVE domain family, member 2 TROVE2 6738 NM_001042369 /// NM_001042370 /// NM_001173524 /// NM_001173525 /// NM_004600 /// NR_033393 /// XM_006711495 /// XM_006711496 /// XM_006711497 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207521_s_at AF068220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068220.1 /DEF=Homo sapiens sarco-endoplasmic reticulum Ca-ATPase 3 (ATP2A3) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=ATP2A3 /PROD=sarco-endoplasmic reticulum Ca-ATPase 3 /DB_XREF=gi:3211976 /UG=Hs.5541 ATPase, Ca++ transporting, ubiquitous /FL=gb:AF068220.1 gb:NM_005173.1 AF068220 ATPase, Ca++ transporting, ubiquitous ATP2A3 489 NM_005173 /// NM_174953 /// NM_174954 /// NM_174955 /// NM_174956 /// NM_174957 /// NM_174958 /// XM_005256656 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207522_s_at NM_005173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005173.1 /DEF=Homo sapiens ATPase, Ca++ transporting, ubiquitous (ATP2A3), mRNA. /FEA=mRNA /GEN=ATP2A3 /PROD=ATPase, Ca++ transporting, ubiquitous /DB_XREF=gi:4885076 /UG=Hs.5541 ATPase, Ca++ transporting, ubiquitous /FL=gb:AF068220.1 gb:NM_005173.1 NM_005173 ATPase, Ca++ transporting, ubiquitous ATP2A3 489 NM_005173 /// NM_174953 /// NM_174954 /// NM_174955 /// NM_174956 /// NM_174957 /// NM_174958 /// XM_005256656 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207523_at NM_006781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006781.1 /DEF=Homo sapiens testis specific basic protein (TSBP), mRNA. /FEA=mRNA /GEN=TSBP /PROD=testis specific basic protein /DB_XREF=gi:11321623 /UG=Hs.57692 chromosome 6 open reading frame 10 /FL=gb:NM_006781.1 gb:U60665.1 NM_006781 chromosome 6 open reading frame 10 C6orf10 10665 NM_001286474 /// NM_001286475 /// NM_006781 /// XM_005248810 /// XM_005274912 /// XM_005275078 /// XM_005275342 /// XM_006714958 /// XM_006714959 /// XM_006714960 /// XM_006714961 /// XM_006714962 /// XM_006714963 /// XM_006714964 /// XM_006714965 /// XM_006725466 /// XM_006725673 /// XM_006725674 /// XM_006725675 /// XM_006725676 /// XM_006725677 /// XM_006725678 /// XM_006725679 /// XM_006725680 /// XM_006725681 /// XM_006725795 /// XM_006725796 /// XM_006725797 /// XM_006725798 /// XM_006725799 /// XM_006725800 /// XM_006725801 /// XM_006725802 /// XM_006725803 /// XM_006725972 /// XM_006725973 /// XM_006725974 /// XM_006725975 /// XM_006725976 /// XM_006725977 /// XM_006725978 /// XM_006725979 /// XM_006725980 /// XM_006726073 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207524_at NM_021908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021908.1 /DEF=Homo sapiens suppression of tumorigenicity 7 (ST7), transcript variant b, mRNA. /FEA=mRNA /GEN=ST7 /PROD=suppression of tumorigenicity 7, isoform b /DB_XREF=gi:11761625 /UG=Hs.5814 suppression of tumorigenicity 7 /FL=gb:NM_021908.1 gb:AF234883.1 NM_021908 microRNA 6132 /// suppression of tumorigenicity 7 /// ST7 overlapping transcript 3 MIR6132 /// ST7 /// ST7-OT3 7982 /// 93655 /// 102466616 NM_018412 /// NM_021908 /// NR_002332 /// NR_106748 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207525_s_at NM_005716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005716.1 /DEF=Homo sapiens chromosome 19 open reading frame 3 (C19ORF3), mRNA. /FEA=mRNA /GEN=C19ORF3 /PROD=GLUT1 C-terminal binding protein /DB_XREF=gi:5031714 /UG=Hs.6454 chromosome 19 open reading frame 3 /FL=gb:AF089816.1 gb:NM_005716.1 NM_005716 GIPC PDZ domain containing family, member 1 GIPC1 10755 NM_005716 /// NM_202467 /// NM_202468 /// NM_202469 /// NM_202470 /// NM_202494 0006605 // protein targeting // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0014047 // glutamate secretion // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005903 // brush border // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 207526_s_at NM_003856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003856.1 /DEF=Homo sapiens interleukin 1 receptor-like 1 (IL1RL1), mRNA. /FEA=mRNA /GEN=IL1RL1 /PROD=interleukin 1 receptor-like 1 /DB_XREF=gi:4507244 /UG=Hs.66 interleukin 1 receptor-like 1 /FL=gb:NM_003856.1 NM_003856 interleukin 1 receptor-like 1 IL1RL1 9173 NM_001282408 /// NM_003856 /// NM_016232 /// NM_173459 /// NR_104167 /// XM_006712839 0002826 // negative regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0038172 // interleukin-33-mediated signaling pathway // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002113 // interleukin-33 binding // inferred from electronic annotation /// 0002114 // interleukin-33 receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207527_at NM_004983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004983.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 9 (KCNJ9), mRNA. /FEA=mRNA /GEN=KCNJ9 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 9 /DB_XREF=gi:4826803 /UG=Hs.66726 potassium inwardly-rectifying channel, subfamily J, member 9 /FL=gb:U52152.1 gb:NM_004983.1 NM_004983 potassium inwardly-rectifying channel, subfamily J, member 9 KCNJ9 3765 NM_004983 /// XM_006711305 /// XM_006711306 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 207528_s_at NM_014331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014331.1 /DEF=Homo sapiens solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (SLC7A11), mRNA. /FEA=mRNA /GEN=SLC7A11 /PROD=solute carrier family 7, (cationic amino acidtransporter, y+ system) member 11 /DB_XREF=gi:7657682 /UG=Hs.6682 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 /FL=gb:AF200708.1 gb:AB026891.1 gb:NM_014331.1 NM_014331 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 SLC7A11 23657 NM_014331 /// XM_005262875 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0015813 // L-glutamate transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015327 // cystine:glutamate antiporter activity // traceable author statement 207529_at NM_021010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021010.1 /DEF=Homo sapiens defensin, alpha 5, Paneth cell-specific (DEFA5), mRNA. /FEA=mRNA /GEN=DEFA5 /PROD=defensin, alpha 5, preproprotein /DB_XREF=gi:10337584 /UG=Hs.72887 defensin, alpha 5, Paneth cell-specific /FL=gb:NM_021010.1 NM_021010 defensin, alpha 5, Paneth cell-specific DEFA5 1670 NM_021010 0006952 // defense response // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement 207530_s_at NM_004936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004936.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (CDKN2B), mRNA. /FEA=mRNA /GEN=CDKN2B /PROD=cyclin-dependent kinase inhibitor 2B (p15,inhibits CDK4) /DB_XREF=gi:11386206 /UG=Hs.72901 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) /FL=gb:NM_004936.1 gb:L36844.1 gb:U17075.1 NM_004936 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) CDKN2B 1030 NM_004936 /// NM_078487 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030219 // megakaryocyte differentiation // inferred from expression pattern /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from mutant phenotype /// 0031670 // cellular response to nutrient // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048536 // spleen development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // non-traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 207531_at NM_020989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020989.2 /DEF=Homo sapiens crystallin, gamma C (CRYGC), mRNA. /FEA=mRNA /GEN=CRYGC /PROD=crystallin, gamma C /DB_XREF=gi:13377000 /UG=Hs.72910 crystallin, gamma C /FL=gb:NM_020989.2 gb:U66582.1 NM_020989 crystallin, gamma C CRYGC 1420 NM_020989 0001654 // eye development // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005212 // structural constituent of eye lens // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207532_at NM_006891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006891.2 /DEF=Homo sapiens crystallin, gamma D (CRYGD), mRNA. /FEA=mRNA /GEN=CRYGD /PROD=crystallin, gamma D /DB_XREF=gi:13377001 /UG=Hs.72911 crystallin, gamma D /FL=gb:NM_006891.2 gb:U66583.1 NM_006891 crystallin, gamma D CRYGD 1421 NM_006891 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from mutant phenotype /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005212 // structural constituent of eye lens // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207533_at NM_002981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002981.1 /DEF=Homo sapiens small inducible cytokine A1 (I-309, homologous to mouse Tca-3) (SCYA1), mRNA. /FEA=mRNA /GEN=SCYA1 /PROD=small inducible cytokine A1 (I-309, homologousto mouse Tca-3) /DB_XREF=gi:4506832 /UG=Hs.72918 small inducible cytokine A1 (I-309, homologous to mouse Tca-3) /FL=gb:M57502.1 gb:NM_002981.1 NM_002981 chemokine (C-C motif) ligand 1 CCL1 6346 NM_002981 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 207534_at NM_002363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002363.1 /DEF=Homo sapiens melanoma antigen, family B, 1 (MAGEB1), mRNA. /FEA=mRNA /GEN=MAGEB1 /PROD=melanoma antigen, family B, 1 /DB_XREF=gi:4505078 /UG=Hs.73021 melanoma antigen, family B, 1 /FL=gb:NM_002363.1 NM_002363 melanoma antigen family B, 1 MAGEB1 4112 NM_002363 /// NM_177404 /// NM_177415 207535_s_at NM_002502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002502.1 /DEF=Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49p100) (NFKB2), mRNA. /FEA=mRNA /GEN=NFKB2 /PROD=nuclear factor of kappa light polypeptide geneenhancer in B-cells 2 (p49p100) /DB_XREF=gi:4505382 /UG=Hs.73090 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49p100) /FL=gb:NM_002502.1 NM_002502 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) NFKB2 4791 NM_001077494 /// NM_001261403 /// NM_001288724 /// NM_002502 /// XM_005269860 /// XM_005269861 /// XM_006717869 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002268 // follicular dendritic cell differentiation // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048536 // spleen development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0033257 // Bcl3/NF-kappaB2 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207536_s_at NM_001561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001561.2 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 9 (TNFRSF9), mRNA. /FEA=mRNA /GEN=TNFRSF9 /PROD=interleukin-activated receptor, homolog of mouseLy63 /DB_XREF=gi:5730094 /UG=Hs.73895 tumor necrosis factor receptor superfamily, member 9 /FL=gb:L12964.2 gb:U03397.1 gb:NM_001561.2 NM_001561 tumor necrosis factor receptor superfamily, member 9 TNFRSF9 3604 NM_001561 /// XM_006710618 0006915 // apoptotic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 2001180 // negative regulation of interleukin-10 secretion // inferred from electronic annotation /// 2001183 // negative regulation of interleukin-12 secretion // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from electronic annotation 207537_at NM_002625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002625.1 /DEF=Homo sapiens 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 1 (PFKFB1), mRNA. /FEA=mRNA /GEN=PFKFB1 /PROD=6-phosphofructo-2-kinasefructose-2,6-biphosphatase 1 /DB_XREF=gi:4505744 /UG=Hs.739 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 1 /FL=gb:M19938.1 gb:NM_002625.1 NM_002625 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 5207 NM_001271804 /// NM_001271805 /// NM_002625 /// NR_073450 /// XM_005262014 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042594 // response to starvation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043540 // 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // traceable author statement /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from direct assay /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0070095 // fructose-6-phosphate binding // inferred from electronic annotation 207538_at NM_000589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000589.1 /DEF=Homo sapiens interleukin 4 (IL4), mRNA. /FEA=mRNA /GEN=IL4 /PROD=interleukin 4 /DB_XREF=gi:4504668 /UG=Hs.73917 interleukin 4 /FL=gb:M13982.1 gb:NM_000589.1 NM_000589 interleukin 4 IL4 3565 NM_000589 /// NM_172348 /// XR_427710 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002227 // innate immune response in mucosa // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010155 // regulation of proton transport // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030183 // B cell differentiation // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031296 // B cell costimulation // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035745 // T-helper 2 cell cytokine production // inferred from direct assay /// 0042092 // type 2 immune response // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0043031 // negative regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045189 // connective tissue growth factor biosynthetic process // traceable author statement /// 0045191 // regulation of isotype switching // traceable author statement /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from sequence or structural similarity /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from sequence or structural similarity /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0071288 // cellular response to mercury ion // inferred from electronic annotation /// 0097028 // dendritic cell differentiation // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000320 // negative regulation of T-helper 17 cell differentiation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005136 // interleukin-4 receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 207539_s_at NM_000589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000589.1 /DEF=Homo sapiens interleukin 4 (IL4), mRNA. /FEA=mRNA /GEN=IL4 /PROD=interleukin 4 /DB_XREF=gi:4504668 /UG=Hs.73917 interleukin 4 /FL=gb:M13982.1 gb:NM_000589.1 NM_000589 interleukin 4 IL4 3565 NM_000589 /// NM_172348 /// XR_427710 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002227 // innate immune response in mucosa // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010155 // regulation of proton transport // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030183 // B cell differentiation // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031296 // B cell costimulation // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035745 // T-helper 2 cell cytokine production // inferred from direct assay /// 0042092 // type 2 immune response // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0043031 // negative regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045189 // connective tissue growth factor biosynthetic process // traceable author statement /// 0045191 // regulation of isotype switching // traceable author statement /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from sequence or structural similarity /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from sequence or structural similarity /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0071288 // cellular response to mercury ion // inferred from electronic annotation /// 0097028 // dendritic cell differentiation // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000320 // negative regulation of T-helper 17 cell differentiation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005136 // interleukin-4 receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 207540_s_at NM_003177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003177.1 /DEF=Homo sapiens spleen tyrosine kinase (SYK), mRNA. /FEA=mRNA /GEN=SYK /PROD=spleen tyrosine kinase /DB_XREF=gi:4507328 /UG=Hs.74101 spleen tyrosine kinase /FL=gb:NM_003177.1 NM_003177 spleen tyrosine kinase SYK 6850 NM_001135052 /// NM_001174167 /// NM_001174168 /// NM_003177 /// XM_005252147 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001820 // serotonin secretion // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002281 // macrophage activation involved in immune response // inferred from sequence or structural similarity /// 0002283 // neutrophil activation involved in immune response // inferred from sequence or structural similarity /// 0002366 // leukocyte activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002554 // serotonin secretion by platelet // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010543 // regulation of platelet activation // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0032928 // regulation of superoxide anion generation // inferred from sequence or structural similarity /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0043313 // regulation of neutrophil degranulation // inferred from sequence or structural similarity /// 0043366 // beta selection // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045401 // positive regulation of interleukin-3 biosynthetic process // inferred from electronic annotation /// 0045425 // positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050764 // regulation of phagocytosis // inferred from sequence or structural similarity /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071226 // cellular response to molecule of fungal origin // inferred from sequence or structural similarity /// 0090237 // regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0019815 // B cell receptor complex // inferred from electronic annotation /// 0032009 // early phagosome // inferred from sequence or structural similarity /// 0042101 // T cell receptor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 207541_s_at NM_002685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002685.1 /DEF=Homo sapiens polymyositisscleroderma autoantigen 2 (100kD) (PMSCL2), mRNA. /FEA=mRNA /GEN=PMSCL2 /PROD=polymyositisscleroderma autoantigen 2 (100kD) /DB_XREF=gi:4505916 /UG=Hs.75584 polymyositisscleroderma autoantigen 2 (100kD) /FL=gb:L01457.1 gb:NM_002685.1 NM_002685 exosome component 10 EXOSC10 5394 NM_001001998 /// NM_002685 /// XM_005263475 /// XM_005263476 /// XR_426611 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0071028 // nuclear mRNA surveillance // inferred from mutant phenotype /// 0071034 // CUT catabolic process // inferred from mutant phenotype /// 0071035 // nuclear polyadenylation-dependent rRNA catabolic process // inferred from mutant phenotype /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype /// 0071048 // nuclear retention of unspliced pre-mRNA at the site of transcription // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay 0000176 // nuclear exosome (RNase complex) // inferred from electronic annotation /// 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207542_s_at NM_000385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000385.2 /DEF=Homo sapiens aquaporin 1 (channel-forming integral protein, 28kD) (AQP1), mRNA. /FEA=mRNA /GEN=AQP1 /PROD=aquaporin 1 /DB_XREF=gi:4755121 /UG=Hs.74602 aquaporin 1 (channel-forming integral protein, 28kD) /FL=gb:U41517.1 gb:NM_000385.2 NM_000385 aquaporin 1 (Colton blood group) AQP1 358 NM_000385 /// NM_001185060 /// NM_001185061 /// NM_001185062 /// NM_198098 0003097 // renal water transport // inferred from direct assay /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from sequence or structural similarity /// 0006833 // water transport // inferred from direct assay /// 0006833 // water transport // inferred from mutant phenotype /// 0006833 // water transport // traceable author statement /// 0006884 // cell volume homeostasis // inferred from mutant phenotype /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from direct assay /// 0015701 // bicarbonate transport // traceable author statement /// 0015793 // glycerol transport // inferred from direct assay /// 0019725 // cellular homeostasis // inferred from direct assay /// 0021670 // lateral ventricle development // inferred from expression pattern /// 0030157 // pancreatic juice secretion // inferred from expression pattern /// 0030185 // nitric oxide transport // inferred from direct assay /// 0030950 // establishment or maintenance of actin cytoskeleton polarity // inferred from mutant phenotype /// 0033326 // cerebrospinal fluid secretion // inferred from expression pattern /// 0033554 // cellular response to stress // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035377 // transepithelial water transport // inferred from direct assay /// 0035378 // carbon dioxide transmembrane transport // inferred from direct assay /// 0042476 // odontogenesis // inferred from expression pattern /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046878 // positive regulation of saliva secretion // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0055085 // transmembrane transport // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071241 // cellular response to inorganic substance // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071288 // cellular response to mercury ion // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071472 // cellular response to salt stress // inferred from direct assay /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 0071549 // cellular response to dexamethasone stimulus // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype /// 0071805 // potassium ion transmembrane transport // inferred from sequence or structural similarity /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0085018 // maintenance of symbiont-containing vacuole by host // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0020003 // symbiont-containing vacuole // inferred from sequence or structural similarity /// 0020005 // symbiont-containing vacuole membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from mutant phenotype /// 0005372 // water transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0015079 // potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015168 // glycerol transmembrane transporter activity // inferred from direct assay /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // inferred from direct assay /// 0015250 // water channel activity // inferred from mutant phenotype /// 0022857 // transmembrane transporter activity // inferred from direct assay /// 0030184 // nitric oxide transmembrane transporter activity // inferred from direct assay /// 0035379 // carbon dioxide transmembrane transporter activity // inferred from direct assay /// 0035379 // carbon dioxide transmembrane transporter activity // traceable author statement 207543_s_at NM_000917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000917.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I (P4HA1), mRNA. /FEA=mRNA /GEN=P4HA1 /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), alpha polypeptideI /DB_XREF=gi:4505564 /UG=Hs.76768 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I /FL=gb:M24486.1 gb:NM_000917.1 NM_000917 prolyl 4-hydroxylase, alpha polypeptide I P4HA1 5033 NM_000917 /// NM_001017962 /// NM_001142595 /// NM_001142596 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004656 // procollagen-proline 4-dioxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 207544_s_at NM_000672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000672.2 /DEF=Homo sapiens alcohol dehydrogenase 6 (class V) (ADH6), mRNA. /FEA=mRNA /GEN=ADH6 /PROD=class V alcohol dehydrogenase 6 /DB_XREF=gi:11024646 /UG=Hs.76800 alcohol dehydrogenase 6 (class V) /FL=gb:NM_000672.2 NM_000672 alcohol dehydrogenase 6 (class V) ADH6 130 NM_000672 /// NM_001102470 /// XM_005262731 /// XR_244619 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004022 // alcohol dehydrogenase (NAD) activity // inferred from direct assay /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0035276 // ethanol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207545_s_at NM_003744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003744.1 /DEF=Homo sapiens numb (Drosophila) homolog (NUMB), mRNA. /FEA=mRNA /GEN=NUMB /PROD=numb (Drosophila) homolog /DB_XREF=gi:4505478 /UG=Hs.78890 numb (Drosophila) homolog /FL=gb:NM_003744.1 gb:L40393.1 NM_003744 uncharacterized LOC101928143 /// uncharacterized LOC101930388 /// numb homolog (Drosophila) LOC101928143 /// LOC101930388 /// NUMB 8650 /// 101928143 /// 101930388 NM_001005743 /// NM_001005744 /// NM_001005745 /// NM_003744 /// XM_005268142 /// XM_005268143 /// XM_005268144 /// XM_005268145 /// XM_005268146 /// XM_006720283 /// XM_006720284 /// XM_006720285 /// XM_006720286 /// XM_006720287 /// XM_006720288 /// XM_006720289 /// XM_006720290 /// XM_006720291 /// XM_006720292 /// XM_006720293 /// XM_006720294 /// XM_006720295 /// XM_006720296 /// XR_245781 /// XR_245782 /// XR_245783 /// XR_245784 /// XR_248038 /// XR_248039 /// XR_248040 /// XR_248041 /// XR_248042 /// XR_253273 /// XR_253274 /// XR_253275 /// XR_253276 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0021670 // lateral ventricle development // inferred from sequence or structural similarity /// 0021849 // neuroblast division in subventricular zone // inferred from sequence or structural similarity /// 0030862 // positive regulation of polarized epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 207546_at NM_000705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000705.1 /DEF=Homo sapiens ATPase, H+K+ exchanging, beta polypeptide (ATP4B), mRNA. /FEA=mRNA /GEN=ATP4B /PROD=ATPase, H+K+ exchanging, beta polypeptide /DB_XREF=gi:4557338 /UG=Hs.813 ATPase, H+K+ exchanging, beta polypeptide /FL=gb:M75110.1 gb:NM_000705.1 NM_000705 ATPase, H+/K+ exchanging, beta polypeptide ATP4B 496 NM_000705 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008900 // hydrogen:potassium-exchanging ATPase activity // traceable author statement 207547_s_at NM_007177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007177.1 /DEF=Homo sapiens TU3A protein (TU3A), mRNA. /FEA=mRNA /GEN=TU3A /PROD=downregulated in renal cell carcinoma /DB_XREF=gi:6005923 /UG=Hs.8022 TU3A protein /FL=gb:AF089854.1 gb:NM_007177.1 NM_007177 family with sequence similarity 107, member A FAM107A 11170 NM_001076778 /// NM_001282713 /// NM_001282714 /// NM_007177 /// XM_005264835 0001558 // regulation of cell growth // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 207548_at NM_000844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000844.1 /DEF=Homo sapiens glutamate receptor, metabotropic 7 (GRM7), mRNA. /FEA=mRNA /GEN=GRM7 /PROD=glutamate receptor, metabotropic 7 /DB_XREF=gi:4504146 /UG=Hs.83407 glutamate receptor, metabotropic 7 /FL=gb:U92458.1 gb:NM_000844.1 NM_000844 glutamate receptor, metabotropic 7 /// uncharacterized LOC100996542 GRM7 /// LOC100996542 2917 /// 100996542 NM_000844 /// NM_181874 /// NM_181875 /// XM_005265095 /// XR_159402 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // inferred from direct assay /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007614 // short-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0031279 // regulation of cyclase activity // inferred from direct assay /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0050877 // neurological system process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from direct assay /// 0032279 // asymmetric synapse // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // not recorded /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048786 // presynaptic active zone // inferred from sequence or structural similarity 0001642 // group III metabotropic glutamate receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // not recorded /// 0005509 // calcium ion binding // inferred from direct assay /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0010855 // adenylate cyclase inhibitor activity // inferred from direct assay /// 0016595 // glutamate binding // inferred from direct assay /// 0030165 // PDZ domain binding // non-traceable author statement /// 0070905 // serine binding // inferred from direct assay 207549_x_at NM_002389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002389.1 /DEF=Homo sapiens membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) (MCP), mRNA. /FEA=mRNA /GEN=MCP /PROD=membrane cofactor protein (CD46,trophoblast-lymphocyte cross-reactive antigen) /DB_XREF=gi:11321566 /UG=Hs.83532 membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) /FL=gb:NM_002389.1 NM_002389 CD46 molecule, complement regulatory protein CD46 4179 NM_002389 /// NM_153826 /// NM_172350 /// NM_172351 /// NM_172352 /// NM_172353 /// NM_172354 /// NM_172355 /// NM_172356 /// NM_172357 /// NM_172358 /// NM_172359 /// NM_172360 /// NM_172361 0002250 // adaptive immune response // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0032613 // interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035581 // sequestering of extracellular ligand from receptor // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from direct assay /// 0045916 // negative regulation of complement activation // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002079 // inner acrosomal membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 207550_at NM_005373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005373.1 /DEF=Homo sapiens myeloproliferative leukemia virus oncogene (MPL), mRNA. /FEA=mRNA /GEN=MPL /PROD=myeloproliferative leukemia virus oncogene /DB_XREF=gi:4885490 /UG=Hs.84171 myeloproliferative leukemia virus oncogene /FL=gb:M90102.1 gb:NM_005373.1 NM_005373 MPL proto-oncogene, thrombopoietin receptor MPL 4352 NM_005373 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032642 // regulation of chemokine production // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation 207551_s_at NM_006800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006800.1 /DEF=Homo sapiens male-specific lethal-3 (Drosophila)-like 1 (MSL3L1), mRNA. /FEA=mRNA /GEN=MSL3L1 /PROD=male-specific lethal-3 (Drosophila)-like 1 /DB_XREF=gi:5803103 /UG=Hs.88764 male-specific lethal-3 (Drosophila)-like 1 /FL=gb:AF117065.1 gb:NM_006800.1 NM_006800 male-specific lethal 3 homolog (Drosophila) MSL3 10943 NM_001193270 /// NM_001282174 /// NM_006800 /// NM_078628 /// NM_078629 /// NM_078630 /// XM_005274440 /// XM_006724461 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0072487 // MSL complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0035064 // methylated histone binding // inferred from direct assay 207552_at NM_005176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005176.3 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 (ATP5G2), mRNA. /FEA=mRNA /GEN=ATP5G2 /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit c (subunit 9), isoform 2 /DB_XREF=gi:6671590 /UG=Hs.89399 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 /FL=gb:NM_005176.3 NM_005176 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) ATP5G2 517 NM_001002031 /// NM_005176 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 207553_at NM_000912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000912.1 /DEF=Homo sapiens opioid receptor, kappa 1 (OPRK1), mRNA. /FEA=mRNA /GEN=OPRK1 /PROD=opioid receptor, kappa 1 /DB_XREF=gi:4505510 /UG=Hs.89455 opioid receptor, kappa 1 /FL=gb:NM_000912.1 gb:U11053.1 gb:U17298.1 gb:L37362.1 NM_000912 opioid receptor, kappa 1 OPRK1 4986 NM_000912 /// NM_001282904 /// XM_005251252 0006955 // immune response // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007600 // sensory perception // traceable author statement /// 0007610 // behavior // traceable author statement /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0031635 // adenylate cyclase-inhibiting opioid receptor signaling pathway // inferred from direct assay /// 0038003 // opioid receptor signaling pathway // inferred from direct assay /// 0046877 // regulation of saliva secretion // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0038048 // dynorphin receptor activity // inferred from direct assay /// 0038048 // dynorphin receptor activity // inferred from mutant phenotype 207554_x_at NM_001060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001060.1 /DEF=Homo sapiens thromboxane A2 receptor (TBXA2R), mRNA. /FEA=mRNA /GEN=TBXA2R /PROD=thromboxane A2 receptor /DB_XREF=gi:4507380 /UG=Hs.89887 thromboxane A2 receptor /FL=gb:NM_001060.1 gb:D38081.1 gb:U27325.1 NM_001060 thromboxane A2 receptor TBXA2R 6915 NM_001060 /// NM_201636 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0038193 // thromboxane A2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004960 // thromboxane receptor activity // inferred from electronic annotation /// 0004961 // thromboxane A2 receptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207555_s_at U27325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27325.1 /DEF=Human thromboxane A2 receptor mRNA, complete cds. /FEA=mRNA /PROD=thromboxane A2 receptor /DB_XREF=gi:862993 /UG=Hs.89887 thromboxane A2 receptor /FL=gb:NM_001060.1 gb:D38081.1 gb:U27325.1 U27325 thromboxane A2 receptor TBXA2R 6915 NM_001060 /// NM_201636 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0038193 // thromboxane A2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004960 // thromboxane receptor activity // inferred from electronic annotation /// 0004961 // thromboxane A2 receptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207556_s_at NM_003646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003646.1 /DEF=Homo sapiens diacylglycerol kinase, zeta (104kD) (DGKZ), mRNA. /FEA=mRNA /GEN=DGKZ /PROD=diacylglycerol kinase, zeta (104kD) /DB_XREF=gi:4503316 /UG=Hs.89981 diacylglycerol kinase, zeta (104kD) /FL=gb:U51477.1 gb:NM_003646.1 NM_003646 diacylglycerol kinase, zeta DGKZ 8525 NM_001105540 /// NM_001199266 /// NM_001199267 /// NM_001199268 /// NM_003646 /// NM_201532 /// NM_201533 /// XM_005253179 /// XM_005253180 /// XM_005253181 /// XM_005253182 /// XM_006718354 /// XM_006718355 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from genetic interaction /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046834 // lipid phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001727 // lipid kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from direct assay /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207557_s_at NM_001035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001035.1 /DEF=Homo sapiens ryanodine receptor 2 (cardiac) (RYR2), mRNA. /FEA=mRNA /GEN=RYR2 /PROD=ryanodine receptor 2 (cardiac) /DB_XREF=gi:4506756 /UG=Hs.90821 ryanodine receptor 2 (cardiac) /FL=gb:NM_001035.1 NM_001035 ryanodine receptor 2 (cardiac) RYR2 6262 NM_001035 /// XM_006711802 /// XM_006711803 /// XM_006711804 /// XM_006711805 /// XM_006711806 /// XM_006711807 /// XM_006711808 /// XM_006711809 /// XM_006711810 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003220 // left ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0003300 // cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from mutant phenotype /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051284 // positive regulation of sequestering of calcium ion // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from direct assay /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072599 // establishment of protein localization to endoplasmic reticulum // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086029 // Purkinje myocyte to ventricular cardiac muscle cell signaling // inferred from sequence or structural similarity /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 0086094 // positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0097050 // type B pancreatic cell apoptotic process // inferred from mutant phenotype /// 1901896 // positive regulation of calcium-transporting ATPase activity // inferred from direct assay 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0034704 // calcium channel complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from electronic annotation /// 0043924 // suramin binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0048763 // calcium-induced calcium release activity // inferred from direct assay 207558_s_at NM_000325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000325.1 /DEF=Homo sapiens paired-like homeodomain transcription factor 2 (PITX2), mRNA. /FEA=mRNA /GEN=PITX2 /PROD=paired-like homeodomain transcription factor 2 /DB_XREF=gi:4505826 /UG=Hs.92282 paired-like homeodomain transcription factor 2 /FL=gb:U69961.1 gb:AF048720.1 gb:NM_000325.1 NM_000325 paired-like homeodomain 2 PITX2 5308 NM_000325 /// NM_001204397 /// NM_001204398 /// NM_001204399 /// NM_153426 /// NM_153427 /// XM_006714235 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002074 // extraocular skeletal muscle development // inferred from electronic annotation /// 0003171 // atrioventricular valve development // inferred from electronic annotation /// 0003253 // cardiac neural crest cell migration involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021763 // subthalamic nucleus development // inferred from electronic annotation /// 0021855 // hypothalamus cell migration // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035315 // hair cell differentiation // inferred by curator /// 0035886 // vascular smooth muscle cell differentiation // inferred from electronic annotation /// 0035993 // deltoid tuberosity development // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0055123 // digestive system development // inferred from electronic annotation /// 0060126 // somatotropin secreting cell differentiation // traceable author statement /// 0060127 // prolactin secreting cell differentiation // traceable author statement /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060460 // left lung morphogenesis // inferred from electronic annotation /// 0060577 // pulmonary vein morphogenesis // inferred from electronic annotation /// 0060578 // superior vena cava morphogenesis // inferred from electronic annotation /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from mutant phenotype /// 0061325 // cell proliferation involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred by curator /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 207559_s_at NM_005096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005096.1 /DEF=Homo sapiens zinc finger protein 261 (ZNF261), mRNA. /FEA=mRNA /GEN=ZNF261 /PROD=zinc finger protein 261 /DB_XREF=gi:4827066 /UG=Hs.9568 zinc finger protein 261 /FL=gb:AB002383.1 gb:NM_005096.1 NM_005096 zinc finger, MYM-type 3 ZMYM3 9203 NM_001171162 /// NM_001171163 /// NM_005096 /// NM_201599 /// XM_005262309 /// XM_005262310 /// XM_006724715 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207560_at U62966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62966.1 /DEF=Human Na+nucleoside cotransporter (hCNT1a) mRNA, complete cds. /FEA=mRNA /GEN=hCNT1a /PROD=Na+nucleoside cotransporter /DB_XREF=gi:2072781 /UG=Hs.97207 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 /FL=gb:U62966.1 gb:U62967.1 gb:U62968.1 gb:NM_004213.1 U62966 solute carrier family 28 (concentrative nucleoside transporter), member 1 SLC28A1 9154 NM_001287761 /// NM_001287762 /// NM_004213 /// NM_201651 /// XM_005254989 /// XM_005254991 /// XM_005254993 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015858 // nucleoside transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0001882 // nucleoside binding // inferred from electronic annotation /// 0005337 // nucleoside transmembrane transporter activity // traceable author statement /// 0005415 // nucleoside:sodium symporter activity // inferred from electronic annotation 207561_s_at NM_020322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020322.1 /DEF=Homo sapiens amiloride-sensitive cation channel 3, testis (ACCN3), transcript variant 3, mRNA. /FEA=mRNA /GEN=ACCN3 /PROD=testis amiloride-sensitive cation channel 3,isoform c /DB_XREF=gi:9998947 /UG=Hs.98547 amiloride-sensitive cation channel 3, testis /FL=gb:AF195024.1 gb:NM_020322.1 NM_020322 ATP-binding cassette, sub-family B (MDR/TAP), member 8 /// acid-sensing (proton-gated) ion channel 3 ABCB8 /// ASIC3 9311 /// 11194 NM_001282291 /// NM_001282292 /// NM_001282293 /// NM_004769 /// NM_007188 /// NM_020321 /// NM_020322 /// NR_046401 0001101 // response to acid // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007600 // sensory perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042930 // enterobactin transport // inferred from electronic annotation /// 0050907 // detection of chemical stimulus involved in sensory perception // inferred from electronic annotation /// 0050915 // sensory perception of sour taste // inferred from mutant phenotype /// 0050961 // detection of temperature stimulus involved in sensory perception // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050968 // detection of chemical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050974 // detection of mechanical stimulus involved in sensory perception // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005261 // cation channel activity // traceable author statement /// 0005272 // sodium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015280 // ligand-gated sodium channel activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded /// 0042931 // enterobactin transporter activity // inferred from electronic annotation 207562_at NM_001347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001347.1 /DEF=Homo sapiens diacylglycerol kinase, theta (110kD) (DGKQ), mRNA. /FEA=mRNA /GEN=DGKQ /PROD=diacylglycerol kinase, theta (110kD) /DB_XREF=gi:4557518 /UG=Hs.99932 diacylglycerol kinase, theta (110kD) /FL=gb:NM_001347.1 gb:L38707.1 NM_001347 diacylglycerol kinase, theta 110kDa DGKQ 1609 NM_001347 /// XM_006713863 /// XR_427469 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0033198 // response to ATP // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207563_s_at U77413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U77413.1 /DEF=Human O-linked GlcNAc transferase mRNA, complete cds. /FEA=mRNA /PROD=O-linked GlcNAc transferase /DB_XREF=gi:2266993 /UG=Hs.100293 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) /FL=gb:U77413.1 gb:NM_003605.2 U77413 O-linked N-acetylglucosamine (GlcNAc) transferase OGT 8473 NM_003605 /// NM_181672 /// NM_181673 /// XM_005262308 /// XM_006724714 0006110 // regulation of glycolytic process // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from sequence or structural similarity 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070688 // MLL5-L complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay /// 0097363 // protein O-GlcNAc transferase activity // inferred from sequence or structural similarity 207564_x_at NM_003605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003605.2 /DEF=Homo sapiens O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT), mRNA. /FEA=mRNA /GEN=OGT /PROD=O-linked GlcNAc transferase /DB_XREF=gi:6006036 /UG=Hs.100293 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) /FL=gb:U77413.1 gb:NM_003605.2 NM_003605 O-linked N-acetylglucosamine (GlcNAc) transferase OGT 8473 NM_003605 /// NM_181672 /// NM_181673 /// XM_005262308 /// XM_006724714 0006110 // regulation of glycolytic process // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from sequence or structural similarity 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070688 // MLL5-L complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay /// 0097363 // protein O-GlcNAc transferase activity // inferred from sequence or structural similarity 207565_s_at NM_001531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001531.1 /DEF=Homo sapiens major histocompatibility complex, class I-like sequence (HLALS), mRNA. /FEA=mRNA /GEN=HLALS /PROD=major histocompatibility complex, class I-likesequence /DB_XREF=gi:4504416 /UG=Hs.101840 major histocompatibility complex, class I-like sequence /FL=gb:NM_001531.1 gb:U22963.1 NM_001531 major histocompatibility complex, class I-related MR1 3140 NM_001194999 /// NM_001195000 /// NM_001195035 /// NM_001531 /// XM_005245115 /// XM_006711286 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032620 // interleukin-17 production // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032393 // MHC class I receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 207566_at NM_001531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001531.1 /DEF=Homo sapiens major histocompatibility complex, class I-like sequence (HLALS), mRNA. /FEA=mRNA /GEN=HLALS /PROD=major histocompatibility complex, class I-likesequence /DB_XREF=gi:4504416 /UG=Hs.101840 major histocompatibility complex, class I-like sequence /FL=gb:NM_001531.1 gb:U22963.1 NM_001531 major histocompatibility complex, class I-related MR1 3140 NM_001194999 /// NM_001195000 /// NM_001195035 /// NM_001531 /// XM_005245115 /// XM_006711286 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032620 // interleukin-17 production // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032393 // MHC class I receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 207567_at NM_003984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003984.1 /DEF=Homo sapiens solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 (SLC13A2), mRNA. /FEA=mRNA /GEN=SLC13A2 /PROD=solute carrier family 13 (sodium-dependentdicarboxylate transporter), member 2 /DB_XREF=gi:4506978 /UG=Hs.102307 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 /FL=gb:U26209.1 gb:NM_003984.1 NM_003984 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 SLC13A2 9058 NM_001145975 /// NM_001145976 /// NM_003984 /// NR_027384 /// XM_006722165 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015361 // low affinity sodium:dicarboxylate symporter activity // traceable author statement 207568_at NM_004198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004198.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 6 (CHRNA6), mRNA. /FEA=mRNA /GEN=CHRNA6 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 6 /DB_XREF=gi:4757981 /UG=Hs.103128 cholinergic receptor, nicotinic, alpha polypeptide 6 /FL=gb:U62435.1 gb:NM_004198.1 NM_004198 cholinergic receptor, nicotinic, alpha 6 (neuronal) CHRNA6 8973 NM_001199279 /// NM_004198 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // traceable author statement 207569_at NM_002944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002944.1 /DEF=Homo sapiens v-ros avian UR2 sarcoma virus oncogene homolog 1 (ROS1), mRNA. /FEA=mRNA /GEN=ROS1 /PROD=v-ros avian UR2 sarcoma virus oncogene homolog1 /DB_XREF=gi:4506578 /UG=Hs.1041 v-ros avian UR2 sarcoma virus oncogene homolog 1 /FL=gb:M34353.1 gb:NM_002944.1 NM_002944 ROS proto-oncogene 1 , receptor tyrosine kinase ROS1 6098 NM_002944 /// XM_006715548 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002066 // columnar/cuboidal epithelial cell development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0009750 // response to fructose // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010966 // regulation of phosphate transport // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0032006 // regulation of TOR signaling // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from direct assay /// 0042289 // MHC class II protein binding // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from direct assay 207570_at NM_000451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000451.2 /DEF=Homo sapiens short stature homeobox (SHOX), transcript variant SHOXa, mRNA. /FEA=mRNA /GEN=SHOX /PROD=short stature homeobox, isoform a /DB_XREF=gi:6031201 /UG=Hs.105932 short stature homeobox /FL=gb:U89331.1 gb:NM_000451.2 NM_000451 short stature homeobox SHOX 6473 NM_000451 /// NM_006883 /// XR_247282 /// XR_247322 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207571_x_at NM_004848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004848.1 /DEF=Homo sapiens basement membrane-induced gene (ICB-1), mRNA. /FEA=mRNA /GEN=ICB-1 /PROD=basement membrane-induced gene /DB_XREF=gi:4758579 /UG=Hs.10649 basement membrane-induced gene /FL=gb:AF044896.1 gb:NM_004848.1 NM_004848 thymocyte selection associated family member 2 THEMIS2 9473 NM_001039477 /// NM_001105556 /// NM_001286113 /// NM_001286115 /// NM_004848 /// XM_005246041 /// XM_006711050 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207572_at NM_024716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024716.1 /DEF=Homo sapiens hypothetical protein FLJ23505 (FLJ23505), mRNA. /FEA=mRNA /GEN=FLJ23505 /PROD=hypothetical protein FLJ23505 /DB_XREF=gi:13376018 /UG=Hs.107308 hypothetical protein FLJ23505 /FL=gb:NM_024716.1 NM_024716 EF-hand calcium binding domain 2 EFCAB2 84288 NM_001143943 /// NM_001290327 /// NM_032328 /// NR_026586 /// NR_026587 /// NR_026588 /// XM_006711830 /// XM_006711831 /// XM_006711832 /// XM_006711833 0005509 // calcium ion binding // inferred from electronic annotation 207573_x_at NM_006476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006476.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1F0, subunit g (ATP5JG), mRNA. /FEA=mRNA /GEN=ATP5JG /PROD=ATP synthase, H+ transporting, mitochondrialF1F0, subunit g /DB_XREF=gi:5453560 /UG=Hs.107476 ATP synthase, H+ transporting, mitochondrial F1F0, subunit g /FL=gb:AF092124.1 gb:NM_006476.1 NM_006476 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G ATP5L 10632 NM_006476 /// NR_033759 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 207574_s_at NM_015675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015675.1 /DEF=Homo sapiens growth arrest and DNA-damage-inducible, beta (GADD45B), mRNA. /FEA=mRNA /GEN=GADD45B /PROD=DKFZP566B133 protein /DB_XREF=gi:9945331 /UG=Hs.110571 growth arrest and DNA-damage-inducible, beta /FL=gb:AF090950.1 gb:NM_015675.1 NM_015675 growth arrest and DNA-damage-inducible, beta GADD45B 4616 NM_015675 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 207575_at NM_018652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018652.1 /DEF=Homo sapiens golgin-like protein (GLP), mRNA. /FEA=mRNA /GEN=GLP /PROD=golgin-like protein /DB_XREF=gi:8923698 /UG=Hs.112145 golgin-like protein /FL=gb:AF263742.1 gb:NM_018652.1 NM_018652 golgin A6 family, member A GOLGA6A 342096 NM_001038640 0005794 // Golgi apparatus // inferred from electronic annotation 207576_x_at NM_000915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000915.2 /DEF=Homo sapiens oxytocin, prepro- (neurophysin I) (OXT), mRNA. /FEA=mRNA /GEN=OXT /PROD=oxytocin-neurophysin I preproprotein /DB_XREF=gi:12707574 /UG=Hs.113216 oxytocin, prepro- (neurophysin I) /FL=gb:NM_000915.2 gb:M25650.1 NM_000915 oxytocin/neurophysin I prepropeptide OXT 5020 NM_000915 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010701 // positive regulation of norepinephrine secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032308 // positive regulation of prostaglandin secretion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0034695 // response to prostaglandin E // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044058 // regulation of digestive system process // inferred from electronic annotation /// 0045472 // response to ether // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0060450 // positive regulation of hindgut contraction // inferred from electronic annotation /// 0060455 // negative regulation of gastric acid secretion // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005185 // neurohypophyseal hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0031855 // oxytocin receptor binding // inferred from electronic annotation 207577_at AJ131724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ131724.1 /DEF=Homo sapiens mRNA for serotonin receptor 5-HT4 (splice variant h5-HT4(b)). /FEA=mRNA /GEN=htr4 /PROD=serotonin receptor 5-HT4 /DB_XREF=gi:12053629 /UG=Hs.113262 5-hydroxytryptamine (serotonin) receptor 4 /FL=gb:NM_000870.1 AJ131724 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled HTR4 3360 NM_000870 /// NM_001040169 /// NM_001040172 /// NM_001040173 /// NM_001040174 /// NM_001286410 /// NM_199453 /// NR_104445 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0032098 // regulation of appetite // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 207578_s_at NM_000870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000870.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 4 (HTR4), mRNA. /FEA=mRNA /GEN=HTR4 /PROD=5-hydroxytryptamine (serotonin) receptor 4 /DB_XREF=gi:11321562 /UG=Hs.113262 5-hydroxytryptamine (serotonin) receptor 4 /FL=gb:NM_000870.1 NM_000870 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled HTR4 3360 NM_000870 /// NM_001040169 /// NM_001040172 /// NM_001040173 /// NM_001040174 /// NM_001286410 /// NM_199453 /// NR_104445 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0032098 // regulation of appetite // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 207579_at NM_002365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002365.1 /DEF=Homo sapiens melanoma antigen, family B, 3 (MAGEB3), mRNA. /FEA=mRNA /GEN=MAGEB3 /PROD=melanoma antigen, family B, 3 /DB_XREF=gi:4505082 /UG=Hs.113290 melanoma antigen, family B, 3 /FL=gb:NM_002365.1 NM_002365 melanoma antigen family B, 3 MAGEB3 4114 NM_002365 /// XM_005274510 207580_at NM_002367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002367.1 /DEF=Homo sapiens melanoma antigen, family B, 4 (MAGEB4), mRNA. /FEA=mRNA /GEN=MAGEB4 /PROD=melanoma antigen, family B, 4 /DB_XREF=gi:4505084 /UG=Hs.113291 melanoma antigen, family B, 4 /FL=gb:NM_002367.1 NM_002367 melanoma antigen family B, 4 MAGEB4 4115 NM_002367 207581_s_at NM_002367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002367.1 /DEF=Homo sapiens melanoma antigen, family B, 4 (MAGEB4), mRNA. /FEA=mRNA /GEN=MAGEB4 /PROD=melanoma antigen, family B, 4 /DB_XREF=gi:4505084 /UG=Hs.113291 melanoma antigen, family B, 4 /FL=gb:NM_002367.1 NM_002367 melanoma antigen family B, 4 MAGEB4 4115 NM_002367 207582_at NM_006222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006222.1 /DEF=Homo sapiens protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1-like (PIN1L), mRNA. /FEA=mRNA /GEN=PIN1L /PROD=protein (peptidyl-prolyl cistrans isomerase)NIMA-interacting 1-like /DB_XREF=gi:5453899 /UG=Hs.116993 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1-like /FL=gb:U82382.1 gb:NM_006222.1 NM_006222 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 PIN1P1 5301 NR_023916 207583_at NM_005164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005164.1 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), mRNA. /FEA=mRNA /GEN=ABCD2 /PROD=ATP-binding cassette, sub-family D, member 2 /DB_XREF=gi:9945307 /UG=Hs.117852 ATP-binding cassette, sub-family D (ALD), member 2 /FL=gb:NM_005164.1 NM_005164 ATP-binding cassette, sub-family D (ALD), member 2 ABCD2 225 NM_005164 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from direct assay /// 0042760 // very long-chain fatty acid catabolic process // inferred from genetic interaction /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 207584_at NM_005577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005577.1 /DEF=Homo sapiens lipoprotein, Lp(a) (LPA), mRNA. /FEA=mRNA /GEN=LPA /PROD=lipoprotein, Lp(a) /DB_XREF=gi:5031884 /UG=Hs.119520 lipoprotein, Lp(a) /FL=gb:NM_005577.1 NM_005577 lipoprotein, Lp(a) LPA 4018 NM_005577 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0034358 // plasma lipoprotein particle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction 207585_s_at NM_001001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001001.1 /DEF=Homo sapiens ribosomal protein L36a (RPL36A), mRNA. /FEA=mRNA /GEN=RPL36A /PROD=ribosomal protein L36a /DB_XREF=gi:4506650 /UG=Hs.118857 ribosomal protein L36a /FL=gb:M15661.1 gb:NM_001001.1 NM_001001 ribosomal protein L36a-like RPL36AL 6166 NM_001001 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 207586_at NM_000193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000193.1 /DEF=Homo sapiens sonic hedgehog (Drosophila) homolog (SHH), mRNA. /FEA=mRNA /GEN=SHH /PROD=sonic hedgehog (Drosophila) homolog /DB_XREF=gi:4506938 /UG=Hs.121539 sonic hedgehog (Drosophila) homolog /FL=gb:NM_000193.1 gb:L38518.1 NM_000193 sonic hedgehog SHH 6469 NM_000193 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from mutant phenotype /// 0003140 // determination of left/right asymmetry in lateral mesoderm // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0007228 // positive regulation of hh target transcription factor activity // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007398 // ectoderm development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007418 // ventral midline development // traceable author statement /// 0007442 // hindgut morphogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // traceable author statement /// 0009949 // polarity specification of anterior/posterior axis // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010463 // mesenchymal cell proliferation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014706 // striated muscle tissue development // inferred from electronic annotation /// 0014858 // positive regulation of skeletal muscle cell proliferation // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016539 // intein-mediated protein splicing // inferred from electronic annotation /// 0021513 // spinal cord dorsal/ventral patterning // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021930 // cerebellar granule cell precursor proliferation // inferred from sequence or structural similarity /// 0021938 // smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation // inferred from electronic annotation /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0021978 // telencephalon regionalization // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030162 // regulation of proteolysis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030539 // male genitalia development // inferred from sequence or structural similarity /// 0030850 // prostate gland development // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0031016 // pancreas development // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033092 // positive regulation of immature T cell proliferation in thymus // inferred from sequence or structural similarity /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042481 // regulation of odontogenesis // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043369 // CD4-positive or CD8-positive, alpha-beta T cell lineage commitment // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from sequence or structural similarity /// 0045060 // negative thymic T cell selection // inferred from sequence or structural similarity /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from direct assay /// 0045880 // positive regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0046639 // negative regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0048468 // cell development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from electronic annotation /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0048864 // stem cell development // inferred from sequence or structural similarity /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from direct assay /// 0060020 // Bergmann glial cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060438 // trachea development // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060447 // bud outgrowth involved in lung branching // inferred from electronic annotation /// 0060458 // right lung development // inferred from electronic annotation /// 0060459 // left lung development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060516 // primary prostatic bud elongation // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060685 // regulation of prostatic bud formation // inferred from electronic annotation /// 0060738 // epithelial-mesenchymal signaling involved in prostate gland development // inferred from direct assay /// 0060768 // regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0060769 // positive regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0060782 // regulation of mesenchymal cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0060783 // mesenchymal smoothened signaling pathway involved in prostate gland development // inferred from electronic annotation /// 0060840 // artery development // inferred from electronic annotation /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from electronic annotation /// 0061053 // somite development // inferred from sequence or structural similarity /// 0061189 // positive regulation of sclerotome development // inferred from direct assay /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0072001 // renal system development // inferred from expression pattern /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0080125 // multicellular structure septum development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from sequence or structural similarity /// 1900175 // regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // non-traceable author statement /// 1900180 // regulation of protein localization to nucleus // inferred from direct assay /// 2000062 // negative regulation of ureter smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000063 // positive regulation of ureter smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000357 // negative regulation of kidney smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000358 // positive regulation of kidney smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000729 // positive regulation of mesenchymal cell proliferation involved in ureter development // inferred from sequence or structural similarity /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from direct assay /// 0005113 // patched binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016015 // morphogen activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043237 // laminin-1 binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 207587_at NM_014617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014617.2 /DEF=Homo sapiens crystallin, gamma A (CRYGA), mRNA. /FEA=mRNA /GEN=CRYGA /PROD=crystallin, gamma A /DB_XREF=gi:13376998 /UG=Hs.122566 crystallin, gamma A /FL=gb:NM_014617.2 NM_014617 crystallin, gamma A CRYGA 1418 NM_014617 /// XM_005246326 0001654 // eye development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007601 // visual perception // non-traceable author statement 0005212 // structural constituent of eye lens // non-traceable author statement 207588_at NM_003871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003871.1 /DEF=Homo sapiens myelin transcription factor 2 (MYT2), mRNA. /FEA=mRNA /GEN=MYT2 /PROD=myelin transcription factor 2 /DB_XREF=gi:4505320 /UG=Hs.123048 myelin transcription factor 2 /FL=gb:AF006822.1 gb:NM_003871.1 NM_003871 207589_at NM_000679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000679.1 /DEF=Homo sapiens adrenergic, alpha-1B-, receptor (ADRA1B), mRNA. /FEA=mRNA /GEN=ADRA1B /PROD=adrenergic, alpha-1B-, receptor /DB_XREF=gi:4501958 /UG=Hs.123055 adrenergic, alpha-1B-, receptor /FL=gb:NM_000679.1 gb:U03865.1 gb:L31773.1 NM_000679 adrenoceptor alpha 1B ADRA1B 147 NM_000679 /// XM_005265818 /// XM_005265819 /// XM_006714821 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0001987 // vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure // inferred from electronic annotation /// 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007512 // adult heart development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from electronic annotation /// 0045819 // positive regulation of glycogen catabolic process // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 207590_s_at NM_006733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006733.1 /DEF=Homo sapiens FSH primary response (LRPR1, rat) homolog 1 (FSHPRH1), mRNA. /FEA=mRNA /GEN=FSHPRH1 /PROD=FSH primary response (LRPR1, rat) homolog 1 /DB_XREF=gi:5803018 /UG=Hs.123122 FSH primary response (LRPR1, rat) homolog 1 /FL=gb:NM_006733.1 NM_006733 centromere protein I CENPI 2491 NM_006733 /// XM_005262111 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0007548 // sex differentiation // traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034508 // centromere complex assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 207591_s_at NM_006015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006015.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 (SMARCF1), mRNA. /FEA=mRNA /GEN=SMARCF1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily f, member 1 /DB_XREF=gi:5174394 /UG=Hs.123090 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 /FL=gb:AB001895.1 gb:NM_006015.1 NM_006015 AT rich interactive domain 1A (SWI-like) ARID1A 8289 NM_006015 /// NM_018450 /// NM_139135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003205 // cardiac chamber development // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0042766 // nucleosome mobilization // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0090544 // BAF-type complex // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from electronic annotation 207592_s_at NM_001194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001194.1 /DEF=Homo sapiens hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (HCN2), mRNA. /FEA=mRNA /GEN=HCN2 /PROD=hyperpolarization activated cyclicnucleotide-gated potassium channel 2 /DB_XREF=gi:10835003 /UG=Hs.124161 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 /FL=gb:NM_001194.1 gb:AF065164.2 NM_001194 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 HCN2 610 NM_001194 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // not recorded /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from mutant phenotype /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // inferred from mutant phenotype /// 0005261 // cation channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 207593_at NM_022169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022169.1 /DEF=Homo sapiens putative ABC transporter (WHITE2), mRNA. /FEA=mRNA /GEN=WHITE2 /PROD=putative ABC transporter /DB_XREF=gi:11545923 /UG=Hs.126378 putative ABC transporter /FL=gb:NM_022169.1 NM_022169 ATP-binding cassette, sub-family G (WHITE), member 4 ABCG4 64137 NM_001142505 /// NM_022169 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033344 // cholesterol efflux // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 207594_s_at NM_003895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003895.1 /DEF=Homo sapiens synaptojanin 1 (SYNJ1), mRNA. /FEA=mRNA /GEN=SYNJ1 /PROD=synaptojanin 1 /DB_XREF=gi:4507334 /UG=Hs.127416 synaptojanin 1 /FL=gb:AF009040.1 gb:NM_003895.1 NM_003895 synaptojanin 1 SYNJ1 8867 NM_001160302 /// NM_001160306 /// NM_003895 /// NM_203446 /// XM_005261076 /// XM_005261080 /// XM_005261081 /// XM_006724058 /// XM_006724059 /// XM_006724060 /// XM_006724061 /// XM_006724062 /// XM_006724063 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0016191 // synaptic vesicle uncoating // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0048489 // synaptic vesicle transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030117 // membrane coat // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 207595_s_at NM_006132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006132.1 /DEF=Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant BMP1-4, mRNA. /FEA=mRNA /GEN=BMP1 /PROD=bone morphogenetic protein 1, isoform 4,precursor /DB_XREF=gi:5902814 /UG=Hs.1274 bone morphogenetic protein 1 /FL=gb:NM_006132.1 NM_006132 bone morphogenetic protein 1 BMP1 649 NM_001199 /// NM_006128 /// NM_006129 /// NM_006130 /// NM_006131 /// NM_006132 /// NR_033403 /// NR_033404 /// XM_006716386 /// XR_428315 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207596_at NM_018515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018515.1 /DEF=Homo sapiens hypothetical protein PRO2176 (PRO2176), mRNA. /FEA=mRNA /GEN=PRO2176 /PROD=hypothetical protein PRO2176 /DB_XREF=gi:8924125 /UG=Hs.127648 hypothetical protein PRO2176 /FL=gb:AF119865.1 gb:NM_018515.1 NM_018515 solute carrier organic anion transporter family, member 4C1 SLCO4C1 353189 NM_180991 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 207597_at NM_014237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014237.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 18 (ADAM18), mRNA. /FEA=mRNA /GEN=ADAM18 /PROD=a disintegrin and metalloproteinase domain 18preproprotein /DB_XREF=gi:7656860 /UG=Hs.127930 a disintegrin and metalloproteinase domain 18 /FL=gb:NM_014237.1 NM_014237 ADAM metallopeptidase domain 18 ADAM18 8749 NM_001190956 /// NM_014237 /// XR_247133 /// XR_430697 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 207598_x_at NM_005431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005431.1 /DEF=Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 2 (XRCC2), mRNA. /FEA=mRNA /GEN=XRCC2 /PROD=X-ray repair cross complementing protein 2 /DB_XREF=gi:4885656 /UG=Hs.129727 X-ray repair complementing defective repair in Chinese hamster cells 2 /FL=gb:AF035587.1 gb:NM_005431.1 NM_005431 X-ray repair complementing defective repair in Chinese hamster cells 2 XRCC2 7516 NM_005431 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0042148 // strand invasion // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation 207599_at NM_004771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004771.2 /DEF=Homo sapiens matrix metalloproteinase 20 (enamelysin) (MMP20), mRNA. /FEA=mRNA /GEN=MMP20 /PROD=matrix metalloproteinase 20 preproprotein /DB_XREF=gi:13027805 /UG=Hs.129737 matrix metalloproteinase 20 (enamelysin) /FL=gb:NM_004771.2 NM_004771 matrix metallopeptidase 20 MMP20 9313 NM_004771 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070173 // regulation of enamel mineralization // traceable author statement /// 0097186 // amelogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207600_at NM_004977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004977.1 /DEF=Homo sapiens potassium voltage-gated channel, Shaw-related subfamily, member 3 (KCNC3), mRNA. /FEA=mRNA /GEN=KCNC3 /PROD=potassium voltage-gated channel, Shaw-relatedsubfamily, member 3 /DB_XREF=gi:4826787 /UG=Hs.129738 potassium voltage-gated channel, Shaw-related subfamily, member 3 /FL=gb:AF055989.1 gb:NM_004977.1 NM_004977 potassium voltage-gated channel, Shaw-related subfamily, member 3 KCNC3 3748 NM_004977 /// NR_110912 /// XM_006723203 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207601_at NM_014465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014465.1 /DEF=Homo sapiens thyroid hormone slfotransferase (ST1B2), mRNA. /FEA=mRNA /GEN=ST1B2 /PROD=thyroid hormone slfotransferase /DB_XREF=gi:7657620 /UG=Hs.129742 thyroid hormone slfotransferase /FL=gb:U95726.1 gb:D89479.1 gb:NM_014465.1 NM_014465 sulfotransferase family, cytosolic, 1B, member 1 SULT1B1 27284 NM_014465 /// XM_005265676 /// XM_005265677 /// XM_005265678 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0018958 // phenol-containing compound metabolic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0004062 // aryl sulfotransferase activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 207602_at NM_004262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004262.1 /DEF=Homo sapiens airway trypsin-like protease (HAT), mRNA. /FEA=mRNA /GEN=HAT /PROD=airway trypsin-like protease /DB_XREF=gi:4758507 /UG=Hs.132195 airway trypsin-like protease /FL=gb:AB002134.1 gb:NM_004262.1 NM_004262 transmembrane protease, serine 11D TMPRSS11D 9407 NM_004262 /// XM_005265710 0006508 // proteolysis // inferred from direct assay /// 0007585 // respiratory gaseous exchange // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207603_at NM_003615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003615.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), mRNA. /FEA=mRNA /GEN=SLC4A7 /PROD=solute carrier family 4, sodium bicarbonatecotransporter, member 7 /DB_XREF=gi:4507028 /UG=Hs.132904 solute carrier family 4, sodium bicarbonate cotransporter, member 7 /FL=gb:AB012130.1 gb:NM_003615.1 NM_003615 solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 9497 NM_001258379 /// NM_001258380 /// NM_003615 /// XM_005265598 /// XM_005265599 /// XM_005265600 /// XM_005265601 /// XM_006713421 /// XR_245166 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 207604_s_at NM_003615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003615.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), mRNA. /FEA=mRNA /GEN=SLC4A7 /PROD=solute carrier family 4, sodium bicarbonatecotransporter, member 7 /DB_XREF=gi:4507028 /UG=Hs.132904 solute carrier family 4, sodium bicarbonate cotransporter, member 7 /FL=gb:AB012130.1 gb:NM_003615.1 NM_003615 solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 9497 NM_001258379 /// NM_001258380 /// NM_003615 /// XM_005265598 /// XM_005265599 /// XM_005265600 /// XM_005265601 /// XM_006713421 /// XR_245166 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 207605_x_at NM_024498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024498.1 /DEF=Homo sapiens zinc finger protein 117 (HPF9) (ZNF117), mRNA. /FEA=mRNA /GEN=ZNF117 /PROD=zinc finger protein 117 (HPF9) /DB_XREF=gi:13374556 /UG=Hs.133011 zinc finger protein 117 (HPF9) /FL=gb:NM_024498.1 gb:M27879.1 NM_024498 zinc finger protein 117 ZNF117 51351 NM_015852 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207606_s_at NM_018287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018287.1 /DEF=Homo sapiens hypothetical protein FLJ10971 (FLJ10971), mRNA. /FEA=mRNA /GEN=FLJ10971 /PROD=hypothetical protein FLJ10971 /DB_XREF=gi:8922797 /UG=Hs.13531 hypothetical protein FLJ10971 /FL=gb:NM_018287.1 NM_018287 Rho GTPase activating protein 12 ARHGAP12 94134 NM_001270695 /// NM_001270696 /// NM_001270697 /// NM_001270698 /// NM_001270699 /// NM_018287 /// XM_005252644 /// XM_006717540 /// XM_006717541 0002011 // morphogenesis of an epithelial sheet // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 207607_at NM_005170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005170.1 /DEF=Homo sapiens achaete-scute complex (Drosophila) homolog-like 2 (ASCL2), mRNA. /FEA=mRNA /GEN=ASCL2 /PROD=achaete-scute complex homolog-like 2 /DB_XREF=gi:4885664 /UG=Hs.135639 achaete-scute complex (Drosophila) homolog-like 2 /FL=gb:NM_005170.1 NM_005170 achaete-scute family bHLH transcription factor 2 ASCL2 430 NM_005170 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0007422 // peripheral nervous system development // non-traceable author statement /// 0010626 // negative regulation of Schwann cell proliferation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 207608_x_at NM_000761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000761.2 /DEF=Homo sapiens cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 (CYP1A2), mRNA. /FEA=mRNA /GEN=CYP1A2 /PROD=cytochrome P450, subfamily I (aromaticcompound-inducible), polypeptide 2 /DB_XREF=gi:13325061 /UG=Hs.1361 cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 /FL=gb:NM_000761.2 gb:AF182274.1 NM_000761 cytochrome P450, family 1, subfamily A, polypeptide 2 CYP1A2 1544 NM_000761 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0009403 // toxin biosynthetic process // inferred from direct assay /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009820 // alkaloid metabolic process // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071615 // oxidative deethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0032451 // demethylase activity // inferred from direct assay /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207609_s_at AF182274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182274.1 /DEF=Homo sapiens cytochrome P450-1A2 (CYP1A2) mRNA, complete cds. /FEA=mRNA /GEN=CYP1A2 /PROD=cytochrome P450-1A2 /DB_XREF=gi:6470136 /UG=Hs.1361 cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 /FL=gb:NM_000761.2 gb:AF182274.1 AF182274 cytochrome P450, family 1, subfamily A, polypeptide 2 CYP1A2 1544 NM_000761 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0009403 // toxin biosynthetic process // inferred from direct assay /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009820 // alkaloid metabolic process // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071615 // oxidative deethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0032451 // demethylase activity // inferred from direct assay /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207610_s_at NM_013447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013447.1 /DEF=Homo sapiens egf-like module containing, mucin-like, hormone receptor-like sequence 2 (EMR2), mRNA. /FEA=mRNA /GEN=EMR2 /PROD=egf-like module containing, mucin-like, hormonereceptor-like sequence 2 /DB_XREF=gi:7305024 /UG=Hs.137354 egf-like module containing, mucin-like, hormone receptor-like sequence 2 /FL=gb:AF114491.1 gb:NM_013447.1 NM_013447 egf-like module containing, mucin-like, hormone receptor-like 2 EMR2 30817 NM_001271052 /// NM_013447 /// NM_152916 /// NM_152917 /// NM_152918 /// NM_152919 /// NM_152920 /// NM_152921 /// XM_005259884 /// XM_005259885 /// XM_005259886 /// XR_244067 /// XR_244068 /// XR_244069 /// XR_244070 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0071621 // granulocyte chemotaxis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0035374 // chondroitin sulfate binding // inferred from mutant phenotype 207611_at NM_003519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003519.2 /DEF=Homo sapiens H2B histone family, member C (H2BFC), mRNA. /FEA=mRNA /GEN=H2BFC /PROD=H2B histone family, member C /DB_XREF=gi:5579460 /UG=Hs.137594 H2B histone family, member C /FL=gb:NM_003519.2 NM_003519 histone cluster 1, H2bl HIST1H2BL 8340 NM_003519 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207612_at NM_003393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003393.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 8B (WNT8B), mRNA. /FEA=mRNA /GEN=WNT8B /PROD=wingless-type MMTV integration site family,member 8B /DB_XREF=gi:4507930 /UG=Hs.137595 wingless-type MMTV integration site family, member 8B /FL=gb:NM_003393.1 NM_003393 wingless-type MMTV integration site family, member 8B WNT8B 7479 NM_003393 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032355 // response to estradiol // non-traceable author statement /// 0032526 // response to retinoic acid // non-traceable author statement /// 0045165 // cell fate commitment // not recorded /// 0048263 // determination of dorsal identity // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded 207613_s_at NM_015981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015981.1 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase (CaM kinase) II alpha (CAMK2A), mRNA. /FEA=mRNA /GEN=CAMK2A /PROD=calciumcalmodulin-dependent protein kinase IIalpha-B subunit /DB_XREF=gi:7706285 /UG=Hs.143535 calciumcalmodulin-dependent protein kinase (CaM kinase) II alpha /FL=gb:AF145711.1 gb:NM_015981.1 NM_015981 calcium/calmodulin-dependent protein kinase II alpha CAMK2A 815 NM_015981 /// NM_171825 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation 207614_s_at NM_003592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003592.1 /DEF=Homo sapiens cullin 1 (CUL1), mRNA. /FEA=mRNA /GEN=CUL1 /PROD=cullin 1 /DB_XREF=gi:4503160 /UG=Hs.14541 cullin 1 /FL=gb:U58087.1 gb:NM_003592.1 NM_003592 cullin 1 CUL1 8454 NM_003592 /// XM_005250060 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from sequence or structural similarity /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 207615_s_at NM_001214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001214.1 /DEF=Homo sapiens chromosome 16 open reading frame 3 (C16ORF3), mRNA. /FEA=mRNA /GEN=C16ORF3 /PROD=chromosome 16 open reading frame 3 /DB_XREF=gi:4502486 /UG=Hs.14642 chromosome 16 open reading frame 3 /FL=gb:AF050080.1 gb:NM_001214.1 NM_001214 chromosome 16 open reading frame 3 C16orf3 750 NM_001214 /// NR_122031 207616_s_at NM_004180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004180.1 /DEF=Homo sapiens TRAF family member-associated NFKB activator (TANK), mRNA. /FEA=mRNA /GEN=TANK /PROD=TRAF family member-associated NFKB activator /DB_XREF=gi:4759249 /UG=Hs.146847 TRAF family member-associated NFKB activator /FL=gb:U63830.1 gb:NM_004180.1 NM_004180 TRAF family member-associated NFKB activator TANK 10010 NM_001199135 /// NM_004180 /// NM_133484 /// XM_005246206 /// XM_005246207 /// XM_005246208 /// XM_005246210 /// XM_005246211 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207617_at NM_024005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024005.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 (DDX3), transcript variant 1, mRNA. /FEA=mRNA /GEN=DDX3 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /DB_XREF=gi:13514816 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_024005.1 gb:AF000983.1 NM_024005 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 207618_s_at NM_004328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004328.1 /DEF=Homo sapiens BCS1 (yeast homolog)-like (BCS1L), mRNA. /FEA=mRNA /GEN=BCS1L /PROD=BCS1 (yeast homolog)-like /DB_XREF=gi:4757851 /UG=Hs.150922 BCS1 (yeast homolog)-like /FL=gb:AF026849.1 gb:NM_004328.1 NM_004328 BC1 (ubiquinol-cytochrome c reductase) synthesis-like BCS1L 617 NM_001079866 /// NM_001257342 /// NM_001257343 /// NM_001257344 /// NM_004328 /// XM_005246747 /// XM_005246748 /// XM_005246749 /// XM_006712678 /// XR_427105 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0033617 // mitochondrial respiratory chain complex IV assembly // inferred from mutant phenotype /// 0034551 // mitochondrial respiratory chain complex III assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005750 // mitochondrial respiratory chain complex III // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207619_at NM_001525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001525.1 /DEF=Homo sapiens hypocretin (orexin) receptor 1 (HCRTR1), mRNA. /FEA=mRNA /GEN=HCRTR1 /PROD=orexin receptor 1 /DB_XREF=gi:4557636 /UG=Hs.150968 hypocretin (orexin) receptor 1 /FL=gb:AF041243.1 gb:NM_001525.1 NM_001525 hypocretin (orexin) receptor 1 HCRTR1 3061 NM_001525 /// XM_005270790 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007631 // feeding behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0016499 // orexin receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation 207620_s_at NM_003688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003688.1 /DEF=Homo sapiens calciumcalmodulin-dependent serine protein kinase (MAGUK family) (CASK), mRNA. /FEA=mRNA /GEN=CASK /PROD=calciumcalmodulin-dependent serine proteinkinase (MAGUK family) /DB_XREF=gi:4502566 /UG=Hs.151469 calciumcalmodulin-dependent serine protein kinase (MAGUK family) /FL=gb:AF032119.1 gb:NM_003688.1 NM_003688 calcium/calmodulin-dependent serine protein kinase (MAGUK family) CASK 8573 NM_001126054 /// NM_001126055 /// NM_003688 /// XM_005272686 /// XM_006724565 /// XM_006724566 0001953 // negative regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0061045 // negative regulation of wound healing // inferred from mutant phenotype /// 0070509 // calcium ion import // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 0090288 // negative regulation of cellular response to growth factor stimulus // inferred from mutant phenotype 0005604 // basement membrane // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005652 // nuclear lamina // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004385 // guanylate kinase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from electronic annotation 207621_s_at NM_007169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007169.1 /DEF=Homo sapiens phosphatidylethanolamine N-methyltransferase (PEMT), mRNA. /FEA=mRNA /GEN=PEMT /PROD=phosphatidylethanolamine N-methyltransferase /DB_XREF=gi:6005827 /UG=Hs.15192 phosphatidylethanolamine N-methyltransferase /FL=gb:AB029821.1 gb:AF176806.1 gb:NM_007169.1 NM_007169 phosphatidylethanolamine N-methyltransferase PEMT 10400 NM_001267551 /// NM_001267552 /// NM_007169 /// NM_148172 /// NM_148173 /// XM_006721418 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from electronic annotation /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000773 // phosphatidyl-N-methylethanolamine N-methyltransferase activity // inferred from electronic annotation /// 0004608 // phosphatidylethanolamine N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0080101 // phosphatidyl-N-dimethylethanolamine N-methyltransferase activity // inferred from electronic annotation 207622_s_at NM_005692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005692.2 /DEF=Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 2 (ABCF2), mRNA. /FEA=mRNA /GEN=ABCF2 /PROD=ATP-binding cassette, sub-family F, member 2 /DB_XREF=gi:10947136 /UG=Hs.153612 ATP-binding cassette, sub-family F (GCN20), member 2 /FL=gb:NM_005692.2 gb:AL050291.1 NM_005692 ATP-binding cassette, sub-family F (GCN20), member 2 ABCF2 10061 NM_005692 /// NM_007189 /// XM_005249931 /// XM_006715824 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207623_at NM_005692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005692.2 /DEF=Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 2 (ABCF2), mRNA. /FEA=mRNA /GEN=ABCF2 /PROD=ATP-binding cassette, sub-family F, member 2 /DB_XREF=gi:10947136 /UG=Hs.153612 ATP-binding cassette, sub-family F (GCN20), member 2 /FL=gb:NM_005692.2 gb:AL050291.1 NM_005692 ATP-binding cassette, sub-family F (GCN20), member 2 ABCF2 10061 NM_005692 /// NM_007189 /// XM_005249931 /// XM_006715824 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207624_s_at NM_000328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000328.1 /DEF=Homo sapiens retinitis pigmentosa GTPase regulator (RPGR), mRNA. /FEA=mRNA /GEN=RPGR /PROD=retinitis pigmentosa GTPase regulator /DB_XREF=gi:4506580 /UG=Hs.153614 retinitis pigmentosa GTPase regulator /FL=gb:U57629.1 gb:NM_000328.1 NM_000328 retinitis pigmentosa GTPase regulator RPGR 6103 NM_000328 /// NM_001023582 /// NM_001034853 /// XM_005272633 /// XM_006724538 0006886 // intracellular protein transport // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0036126 // sperm flagellum // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207625_s_at NM_005093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005093.1 /DEF=Homo sapiens core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (CBFA2T2), mRNA. /FEA=mRNA /GEN=CBFA2T2 /PROD=core-binding factor, runt domain, alpha subunit2; translocated to, 2 /DB_XREF=gi:4826662 /UG=Hs.153934 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 /FL=gb:AF013970.1 gb:NM_005093.1 NM_005093 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 CBFA2T2 9139 NM_001032999 /// NM_001039709 /// NM_005093 /// NM_175864 /// XM_006723886 /// XM_006723887 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207626_s_at NM_003046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003046.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (SLC7A2), mRNA. /FEA=mRNA /GEN=SLC7A2 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 2 /DB_XREF=gi:4507048 /UG=Hs.153985 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 /FL=gb:U76368.1 gb:NM_003046.1 NM_003046 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 SLC7A2 6542 NM_001008539 /// NM_001164771 /// NM_003046 /// XM_005273609 /// XM_005273610 /// XM_005273611 /// XM_005273612 /// XM_006716389 0002537 // nitric oxide production involved in inflammatory response // inferred from electronic annotation /// 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0015809 // arginine transport // inferred from electronic annotation /// 0015819 // lysine transport // inferred from electronic annotation /// 0015822 // ornithine transport // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000064 // L-ornithine transmembrane transporter activity // inferred from electronic annotation /// 0005289 // high affinity arginine transmembrane transporter activity // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015174 // basic amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation /// 0015189 // L-lysine transmembrane transporter activity // inferred from electronic annotation 207627_s_at NM_005653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005653.1 /DEF=Homo sapiens transcription factor CP2 (TFCP2), mRNA. /FEA=mRNA /GEN=TFCP2 /PROD=transcription factor CP2 /DB_XREF=gi:5032174 /UG=Hs.154970 transcription factor CP2 /FL=gb:U03495.1 gb:NM_005653.1 NM_005653 transcription factor CP2 TFCP2 7024 NM_001173452 /// NM_001173453 /// NM_005653 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 207628_s_at NM_017528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017528.1 /DEF=Homo sapiens putative methyltransferase (HASJ4442), mRNA. /FEA=mRNA /GEN=HASJ4442 /PROD=putative methyltransferase /DB_XREF=gi:8923713 /UG=Hs.155020 putative methyltransferase /FL=gb:NM_017528.1 NM_017528 Williams Beuren syndrome chromosome region 22 WBSCR22 114049 NM_001202560 /// NM_017528 /// NR_037776 /// NR_045512 /// XM_006715847 /// XM_006715848 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207629_s_at NM_004723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004723.1 /DEF=Homo sapiens rhorac guanine nucleotide exchange factor (GEF) 2 (ARHGEF2), mRNA. /FEA=mRNA /GEN=ARHGEF2 /PROD=rhorac guanine nucleotide exchange factor (GEF)2 /DB_XREF=gi:4758671 /UG=Hs.155120 rhorac guanine nucleotide exchange factor (GEF) 2 /FL=gb:U72206.1 gb:NM_004723.1 NM_004723 Rho/Rac guanine nucleotide exchange factor (GEF) 2 ARHGEF2 9181 NM_001162383 /// NM_001162384 /// NM_004723 /// XM_005245587 /// XM_005245588 /// XM_005245589 /// XM_005245590 /// XM_005245591 /// XM_005245592 /// XM_005245593 /// XM_005245594 /// XM_005245595 /// XM_006711622 /// XM_006711623 /// XM_006711624 /// XM_006711625 /// XM_006711626 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from sequence or structural similarity /// 0060547 // negative regulation of necrotic cell death // inferred from sequence or structural similarity /// 0071225 // cellular response to muramyl dipeptide // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0071474 // cellular hyperosmotic response // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from sequence or structural similarity /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // non-traceable author statement /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay 207630_s_at NM_001881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001881.1 /DEF=Homo sapiens cAMP responsive element modulator (CREM), mRNA. /FEA=mRNA /GEN=CREM /PROD=cAMP responsive element modulator /DB_XREF=gi:4503038 /UG=Hs.155924 cAMP responsive element modulator /FL=gb:NM_001881.1 gb:S68271.1 NM_001881 cAMP responsive element modulator CREM 1390 NM_001267562 /// NM_001267563 /// NM_001267564 /// NM_001267565 /// NM_001267566 /// NM_001267567 /// NM_001267568 /// NM_001267569 /// NM_001267570 /// NM_001881 /// NM_181571 /// NM_182717 /// NM_182718 /// NM_182719 /// NM_182720 /// NM_182721 /// NM_182722 /// NM_182723 /// NM_182724 /// NM_182725 /// NM_182769 /// NM_182770 /// NM_182771 /// NM_182772 /// NM_182850 /// NM_182853 /// NM_183011 /// NM_183012 /// NM_183013 /// NM_183060 /// NR_051971 /// NR_051972 /// NR_051973 /// NR_051974 /// NR_051975 /// XM_006717378 /// XM_006717379 /// XM_006717380 /// XM_006717381 /// XM_006717382 /// XM_006717383 /// XM_006717384 /// XM_006717385 /// XM_006717386 /// XM_006717387 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207631_at NM_005821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005821.1 /DEF=Homo sapiens NBR2 (NBR2), mRNA. /FEA=mRNA /GEN=NBR2 /PROD=NBR2 /DB_XREF=gi:5031934 /UG=Hs.156288 NBR2 /FL=gb:U88573.1 gb:NM_005821.1 NM_005821 neighbor of BRCA1 gene 2 (non-protein coding) NBR2 10230 NM_005821 /// NR_003108 207632_at NM_005592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005592.1 /DEF=Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), mRNA. /FEA=mRNA /GEN=MUSK /PROD=muscle, skeletal, receptor tyrosine kinase /DB_XREF=gi:5031926 /UG=Hs.156465 muscle, skeletal, receptor tyrosine kinase /FL=gb:AF006464.1 gb:NM_005592.1 NM_005592 muscle, skeletal, receptor tyrosine kinase MUSK 4593 NM_001166280 /// NM_001166281 /// NM_005592 /// XM_005251994 /// XM_005251995 /// XM_005251996 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from sequence or structural similarity /// 2000541 // positive regulation of protein geranylgeranylation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207633_s_at NM_005592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005592.1 /DEF=Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), mRNA. /FEA=mRNA /GEN=MUSK /PROD=muscle, skeletal, receptor tyrosine kinase /DB_XREF=gi:5031926 /UG=Hs.156465 muscle, skeletal, receptor tyrosine kinase /FL=gb:AF006464.1 gb:NM_005592.1 NM_005592 muscle, skeletal, receptor tyrosine kinase MUSK 4593 NM_001166280 /// NM_001166281 /// NM_005592 /// XM_005251994 /// XM_005251995 /// XM_005251996 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from sequence or structural similarity /// 2000541 // positive regulation of protein geranylgeranylation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207634_at NM_005018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005018.1 /DEF=Homo sapiens programmed cell death 1 (PDCD1), mRNA. /FEA=mRNA /GEN=PDCD1 /PROD=programmed cell death 1 /DB_XREF=gi:4826889 /UG=Hs.158297 programmed cell death 1 /FL=gb:U64863.1 gb:NM_005018.1 NM_005018 programmed cell death 1 PDCD1 5133 NM_005018 /// XM_006712573 /// XM_006724986 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0031295 // T cell costimulation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207635_s_at NM_002238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002238.1 /DEF=Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 1 (KCNH1), mRNA. /FEA=mRNA /GEN=KCNH1 /PROD=potassium voltage-gated channel, subfamily H,member 1 /DB_XREF=gi:4504830 /UG=Hs.158305 potassium voltage-gated channel, subfamily H (eag-related), member 1 /FL=gb:AF078741.1 gb:NM_002238.1 NM_002238 potassium voltage-gated channel, subfamily H (eag-related), member 1 KCNH1 3756 NM_002238 /// NM_172362 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007520 // myoblast fusion // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 207636_at NM_006217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006217.2 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2 (SERPINI2), mRNA. /FEA=mRNA /GEN=SERPINI2 /PROD=protease inhibitor 14 precursor /DB_XREF=gi:10947029 /UG=Hs.158308 serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2 /FL=gb:NM_006217.2 gb:AB006423.1 gb:AF130470.1 NM_006217 serpin peptidase inhibitor, clade I (pancpin), member 2 SERPINI2 5276 NM_001012303 /// NM_006217 0006928 // cellular component movement // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207637_at NM_014653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014653.1 /DEF=Homo sapiens KIAA0789 gene product (KIAA0789), mRNA. /FEA=mRNA /GEN=KIAA0789 /PROD=KIAA0789 gene product /DB_XREF=gi:7662305 /UG=Hs.158319 KIAA0789 gene product /FL=gb:AB018332.1 gb:NM_014653.1 NM_014653 WSC domain containing 2 WSCD2 9671 NM_014653 /// XM_006719702 /// XM_006719703 /// XM_006719704 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207638_at NM_002772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002772.1 /DEF=Homo sapiens protease, serine, 7 (enterokinase) (PRSS7), mRNA. /FEA=mRNA /GEN=PRSS7 /PROD=protease, serine, 7 (enterokinase) /DB_XREF=gi:4506150 /UG=Hs.158333 protease, serine, 7 (enterokinase) /FL=gb:NM_002772.1 gb:U09860.1 NM_002772 transmembrane protease, serine 15 TMPRSS15 5651 NM_002772 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 207639_at NM_003508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003508.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 9 (FZD9), mRNA. /FEA=mRNA /GEN=FZD9 /PROD=frizzled 9 /DB_XREF=gi:4503834 /UG=Hs.158335 frizzled (Drosophila) homolog 9 /FL=gb:U82169.1 gb:NM_003508.1 NM_003508 frizzled class receptor 9 FZD9 8326 NM_003508 0001944 // vasculature development // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007405 // neuroblast proliferation // not recorded /// 0007420 // brain development // not recorded /// 0007611 // learning or memory // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // not recorded /// 0060070 // canonical Wnt signaling pathway // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction 207640_x_at NM_006181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006181.1 /DEF=Homo sapiens netrin 2 (chicken)-like (NTN2L), mRNA. /FEA=mRNA /GEN=NTN2L /PROD=netrin 2 (chicken)-like /DB_XREF=gi:5453809 /UG=Hs.158336 netrin 2 (chicken)-like /FL=gb:U86759.1 gb:NM_006181.1 NM_006181 netrin 3 NTN3 4917 NM_006181 0007411 // axon guidance // non-traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207641_at NM_012452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012452.1 /DEF=Homo sapiens transmembrane activator and CAML interactor (TACI), mRNA. /FEA=mRNA /GEN=TACI /PROD=transmembrane activator and CAML interactor /DB_XREF=gi:6912693 /UG=Hs.158341 transmembrane activator and CAML interactor /FL=gb:AF023614.1 gb:NM_012452.1 NM_012452 tumor necrosis factor receptor superfamily, member 13B TNFRSF13B 23495 NM_012452 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207642_at NM_001524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001524.1 /DEF=Homo sapiens hypocretin (orexin) neuropeptide precursor (HCRT), mRNA. /FEA=mRNA /GEN=HCRT /PROD=orexin precursor /DB_XREF=gi:4557634 /UG=Hs.158348 hypocretin (orexin) neuropeptide precursor /FL=gb:AF041240.1 gb:NM_001524.1 NM_001524 hypocretin (orexin) neuropeptide precursor HCRT 3060 NM_001524 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0008021 // synaptic vesicle // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0031771 // type 1 hypocretin receptor binding // inferred from electronic annotation /// 0031772 // type 2 hypocretin receptor binding // inferred from electronic annotation 207643_s_at NM_001065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001065.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A), mRNA. /FEA=mRNA /GEN=TNFRSF1A /PROD=tumor necrosis factor receptor 1 (55kD) /DB_XREF=gi:4507574 /UG=Hs.159 tumor necrosis factor receptor superfamily, member 1A /FL=gb:NM_001065.1 NM_001065 tumor necrosis factor receptor superfamily, member 1A TNFRSF1A 7132 NM_001065 0001666 // response to hypoxia // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0033013 // tetrapyrrole metabolic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043120 // tumor necrosis factor binding // inferred from electronic annotation 207644_at NM_003923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003923.1 /DEF=Homo sapiens forkhead box H1 (FOXH1), mRNA. /FEA=mRNA /GEN=FOXH1 /PROD=forkhead box H1 /DB_XREF=gi:4503656 /UG=Hs.159251 forkhead box H1 /FL=gb:AF076292.1 gb:NM_003923.1 NM_003923 forkhead box H1 FOXH1 8928 NM_003923 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001568 // blood vessel development // not recorded /// 0001947 // heart looping // not recorded /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003146 // heart jogging // not recorded /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010159 // specification of organ position // not recorded /// 0021508 // floor plate formation // not recorded /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0035054 // embryonic heart tube anterior/posterior pattern specification // not recorded /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048318 // axial mesoderm development // not recorded /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 1900164 // nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // non-traceable author statement /// 2000824 // negative regulation of androgen receptor activity // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0032444 // activin responsive factor complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070410 // co-SMAD binding // inferred from mutant phenotype /// 0070412 // R-SMAD binding // inferred from mutant phenotype /// 0070412 // R-SMAD binding // inferred from physical interaction 207645_s_at NM_004284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004284.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 1-like (CHD1L), mRNA. /FEA=mRNA /GEN=CHD1L /PROD=chromodomain helicase DNA binding protein1-like /DB_XREF=gi:4757977 /UG=Hs.159273 chromodomain helicase DNA binding protein 1-like /FL=gb:AF054177.1 gb:NM_004284.1 NM_004284 chromodomain helicase DNA binding protein 1-like CHD1L 9557 NM_001256336 /// NM_001256337 /// NM_001256338 /// NM_004284 /// NM_024568 /// NR_046070 /// XM_006711636 /// XM_006711637 /// XM_006711638 /// XM_006711639 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from mutant phenotype 207646_s_at AF080597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080597.1 /DEF=Homo sapiens testis-specific chromodomain protein Y isoform 1 (CDY1) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=CDY1 /PROD=testis-specific chromodomain protein Y isoform1 /DB_XREF=gi:4558751 /UG=Hs.159281 chromodomain protein, Y chromosome, 1 /FL=gb:AF000981.1 gb:AF080597.1 gb:NM_004680.1 AF080597 chromodomain protein, Y-linked, 1 /// chromodomain protein, Y-linked, 1B /// chromodomain protein, Y-linked, 2A /// chromodomain protein, Y-linked, 2B CDY1 /// CDY1B /// CDY2A /// CDY2B 9085 /// 9426 /// 203611 /// 253175 NM_001001722 /// NM_001003894 /// NM_001003895 /// NM_004680 /// NM_004825 /// NM_170723 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 207647_at NM_004680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004680.1 /DEF=Homo sapiens chromodomain protein, Y chromosome, 1 (CDY1), mRNA. /FEA=mRNA /GEN=CDY1 /PROD=chromodomain protein, Y chromosome, 1 /DB_XREF=gi:4757965 /UG=Hs.159281 chromodomain protein, Y chromosome, 1 /FL=gb:AF000981.1 gb:AF080597.1 gb:NM_004680.1 NM_004680 chromodomain protein, Y-linked, 1 CDY1 9085 NM_004680 /// NM_170723 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 207648_at NM_001939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001939.1 /DEF=Homo sapiens dystrophin related protein 2 (DRP2), mRNA. /FEA=mRNA /GEN=DRP2 /PROD=dystrophin related protein 2 /DB_XREF=gi:4503392 /UG=Hs.159291 dystrophin related protein 2 /FL=gb:U43519.1 gb:NM_001939.1 NM_001939 dystrophin related protein 2 DRP2 1821 NM_001171184 /// NM_001939 /// XM_006724628 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207649_at NM_003770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003770.2 /DEF=Homo sapiens keratin, hair, acidic, 7 (KRTHA7), mRNA. /FEA=mRNA /GEN=KRTHA7 /PROD=type I hair keratin 7 /DB_XREF=gi:11641408 /UG=Hs.159403 keratin, hair, acidic, 7 /FL=gb:NM_003770.2 NM_003770 keratin 37 KRT37 8688 NM_003770 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207650_x_at NM_000955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000955.1 /DEF=Homo sapiens prostaglandin E receptor 1 (subtype EP1), 42kD (PTGER1), mRNA. /FEA=mRNA /GEN=PTGER1 /PROD=prostaglandin E receptor 1 (subtype EP1), 42kD /DB_XREF=gi:4506252 /UG=Hs.159360 prostaglandin E receptor 1 (subtype EP1), 42kD /FL=gb:L22647.1 gb:NM_000955.1 NM_000955 prostaglandin E receptor 1 (subtype EP1), 42kDa PTGER1 5731 NM_000955 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // inferred from electronic annotation 207651_at NM_013308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013308.1 /DEF=Homo sapiens platelet activating receptor homolog (H963), mRNA. /FEA=mRNA /GEN=H963 /PROD=platelet activating receptor homolog /DB_XREF=gi:7019400 /UG=Hs.159545 platelet activating receptor homolog /FL=gb:AF002986.1 gb:NM_013308.1 NM_013308 G protein-coupled receptor 171 GPR171 29909 NM_013308 /// XM_005247402 /// XM_005247403 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement 207652_s_at NM_004072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004072.1 /DEF=Homo sapiens chemokine-like receptor 1 (CMKLR1), mRNA. /FEA=mRNA /GEN=CMKLR1 /PROD=chemokine-like receptor 1 /DB_XREF=gi:4758013 /UG=Hs.159553 chemokine-like receptor 1 /FL=gb:U79527.1 gb:NM_004072.1 NM_004072 chemokine-like receptor 1 CMKLR1 1240 NM_001142343 /// NM_001142344 /// NM_001142345 /// NM_004072 0001501 // skeletal system development // traceable author statement /// 0006935 // chemotaxis // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0010759 // positive regulation of macrophage chemotaxis // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050848 // regulation of calcium-mediated signaling // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207653_at NM_004474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004474.1 /DEF=Homo sapiens forkhead box D2 (FOXD2), mRNA. /FEA=mRNA /GEN=FOXD2 /PROD=forkhead box D2 /DB_XREF=gi:4758387 /UG=Hs.166188 forkhead box D2 /FL=gb:AF042832.1 gb:NM_004474.1 NM_004474 forkhead box D2 FOXD2 2306 NM_004474 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001755 // neural crest cell migration // not recorded /// 0001822 // kidney development // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007389 // pattern specification process // not recorded /// 0007422 // peripheral nervous system development // not recorded /// 0009790 // embryo development // /// 0030318 // melanocyte differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded /// 0048484 // enteric nervous system development // not recorded /// 0048485 // sympathetic nervous system development // not recorded /// 0048846 // axon extension involved in axon guidance // not recorded /// 0048937 // lateral line nerve glial cell development // not recorded /// 0050935 // iridophore differentiation // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051216 // cartilage development // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207654_x_at NM_001938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001938.1 /DEF=Homo sapiens down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mRNA. /FEA=mRNA /GEN=DR1 /PROD=down-regulator of transcription 1 /DB_XREF=gi:4503380 /UG=Hs.16697 down-regulator of transcription 1, TBP-binding (negative cofactor 2) /FL=gb:M97388.1 gb:NM_001938.1 NM_001938 down-regulator of transcription 1, TBP-binding (negative cofactor 2) DR1 1810 NM_001938 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 207655_s_at NM_013314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013314.1 /DEF=Homo sapiens B cell linker protein (SLP65), mRNA. /FEA=mRNA /GEN=SLP65 /PROD=B cell linker protein /DB_XREF=gi:7019534 /UG=Hs.167746 B cell linker protein /FL=gb:AF068180.1 gb:NM_013314.1 NM_013314 B-cell linker BLNK 29760 NM_001114094 /// NM_001258440 /// NM_001258441 /// NM_001258442 /// NM_013314 /// NR_047680 /// NR_047681 /// NR_047682 /// NR_047683 0006954 // inflammatory response // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from reviewed computational analysis /// 0030183 // B cell differentiation // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042113 // B cell activation // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from reviewed computational analysis /// 0005515 // protein binding // inferred from physical interaction 207656_s_at NM_004035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004035.2 /DEF=Homo sapiens acyl-Coenzyme A oxidase 1, palmitoyl (ACOX1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ACOX1 /PROD=acyl-Coenzyme A oxidase isoform a /DB_XREF=gi:6031153 /UG=Hs.167835 acyl-Coenzyme A oxidase 1, palmitoyl /FL=gb:NM_004035.2 NM_004035 acyl-CoA oxidase 1, palmitoyl ACOX1 51 NM_001185039 /// NM_004035 /// NM_007292 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from genetic interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2000189 // positive regulation of cholesterol homeostasis // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from direct assay /// 0003997 // acyl-CoA oxidase activity // inferred from genetic interaction /// 0003997 // acyl-CoA oxidase activity // inferred from mutant phenotype /// 0003997 // acyl-CoA oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0016401 // palmitoyl-CoA oxidase activity // inferred from direct assay /// 0016401 // palmitoyl-CoA oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 207657_x_at NM_002270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002270.1 /DEF=Homo sapiens karyopherin (importin) beta 2 (KPNB2), mRNA. /FEA=mRNA /GEN=KPNB2 /PROD=karyopherin (importin) beta 2 /DB_XREF=gi:4504906 /UG=Hs.168075 karyopherin (importin) beta 2 /FL=gb:U70322.1 gb:NM_002270.1 NM_002270 transportin 1 TNPO1 3842 NM_002270 /// NM_153188 /// XM_005248500 /// XM_005248501 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207658_s_at NM_004471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004471.1 /DEF=Homo sapiens forkhead box G1A (FOXG1A), mRNA. /FEA=mRNA /GEN=FOXG1A /PROD=forkhead box G1A /DB_XREF=gi:4758389 /UG=Hs.169277 forkhead box G1A /FL=gb:NM_004471.1 NM_004471 forkhead box G1 FOXG1 2290 NM_005249 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from electronic annotation /// 0021852 // pyramidal neuron migration // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207659_s_at NM_006501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006501.1 /DEF=Homo sapiens myelin-associated oligodendrocyte basic protein (MOBP), mRNA. /FEA=mRNA /GEN=MOBP /PROD=myelin-associated oligodendrocyte basic protein /DB_XREF=gi:5729930 /UG=Hs.169309 myelin-associated oligodendrocyte basic protein /FL=gb:NM_006501.1 gb:D28113.1 NM_006501 myelin-associated oligodendrocyte basic protein MOBP 4336 NM_001278322 /// NM_001278323 /// NM_182935 /// NR_003090 /// NR_103504 /// NR_103505 /// NR_103506 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 207660_at NM_004019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004019.1 /DEF=Homo sapiens dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 (DMD), transcript variant Dp40, mRNA. /FEA=mRNA /GEN=DMD /PROD=dystrophin Dp40 isoform /DB_XREF=gi:5032304 /UG=Hs.169470 dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 /FL=gb:NM_004019.1 NM_004019 dystrophin DMD 1756 NM_000109 /// NM_004006 /// NM_004007 /// NM_004009 /// NM_004010 /// NM_004011 /// NM_004012 /// NM_004013 /// NM_004014 /// NM_004015 /// NM_004016 /// NM_004017 /// NM_004018 /// NM_004019 /// NM_004020 /// NM_004021 /// NM_004022 /// NM_004023 /// XM_006724468 /// XM_006724469 /// XM_006724470 /// XM_006724471 /// XM_006724472 /// XM_006724473 /// XM_006724474 /// XM_006724475 /// XM_006724476 /// XR_430491 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014819 // regulation of skeletal muscle contraction // inferred from sequence or structural similarity /// 0014904 // myotube cell development // inferred from electronic annotation /// 0021629 // olfactory nerve structural organization // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity /// 0044458 // motile cilium assembly // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051647 // nucleus localization // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060857 // establishment of glial blood-brain barrier // inferred from electronic annotation /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0090287 // regulation of cellular response to growth factor stimulus // inferred from mutant phenotype /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 2000169 // regulation of peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // non-traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0017022 // myosin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from sequence or structural similarity 207661_s_at NM_014631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014631.1 /DEF=Homo sapiens KIAA0418 gene product (KIAA0418), mRNA. /FEA=mRNA /GEN=KIAA0418 /PROD=KIAA0418 gene product /DB_XREF=gi:7662103 /UG=Hs.173448 KIAA0418 gene product /FL=gb:AB007878.1 gb:NM_014631.1 NM_014631 SH3 and PX domains 2A SH3PXD2A 9644 NM_014631 /// XM_005270294 /// XM_005270295 /// XM_005270297 /// XM_005270298 /// XM_006718079 /// XM_006718080 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation 0002102 // podosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 207662_at NM_005992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005992.1 /DEF=Homo sapiens T-box 1 (TBX1), mRNA. /FEA=mRNA /GEN=TBX1 /PROD=T-box 1 /DB_XREF=gi:5174710 /UG=Hs.173984 T-box 1 /FL=gb:AF012131.1 gb:NM_005992.1 NM_005992 T-box 1 TBX1 6899 NM_005992 /// NM_080646 /// NM_080647 /// XM_005261269 /// XM_006724312 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0021644 // vagus nerve morphogenesis // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042471 // ear morphogenesis // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042473 // outer ear morphogenesis // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043587 // tongue morphogenesis // inferred from sequence or structural similarity /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from mutant phenotype /// 0048644 // muscle organ morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from mutant phenotype /// 0048752 // semicircular canal morphogenesis // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0060017 // parathyroid gland development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from sequence or structural similarity /// 0060415 // muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0070166 // enamel mineralization // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071600 // otic vesicle morphogenesis // inferred from electronic annotation /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0097152 // mesenchymal cell apoptotic process // inferred from sequence or structural similarity /// 2000027 // regulation of organ morphogenesis // inferred from sequence or structural similarity /// 2001037 // positive regulation of tongue muscle cell differentiation // inferred from sequence or structural similarity /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // traceable author statement 207663_x_at NM_001473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001473.1 /DEF=Homo sapiens G antigen 3 (GAGE3), mRNA. /FEA=mRNA /GEN=GAGE3 /PROD=G antigen 3 /DB_XREF=gi:4503880 /UG=Hs.176661 G antigen 3 /FL=gb:NM_001473.1 gb:U19144.1 NM_001473 G antigen 3 GAGE3 2575 207664_at NM_001464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001464.2 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 2 (fertilin beta) (ADAM2), mRNA. /FEA=mRNA /GEN=ADAM2 /PROD=a disintegrin and metalloproteinase domain 2proprotein /DB_XREF=gi:11497606 /UG=Hs.177959 a disintegrin and metalloproteinase domain 2 (fertilin beta) /FL=gb:NM_001464.2 gb:U52370.1 gb:U38805.1 NM_001464 ADAM metallopeptidase domain 2 ADAM2 2515 NM_001278113 /// NM_001278114 /// NM_001464 /// XM_005273468 /// XM_006725119 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 207665_at NM_003813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003813.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 21 (ADAM21), mRNA. /FEA=mRNA /GEN=ADAM21 /PROD=a disintegrin and metalloproteinase domain 21preproprotein /DB_XREF=gi:11497039 /UG=Hs.178748 a disintegrin and metalloproteinase domain 21 /FL=gb:NM_003813.1 NM_003813 ADAM metallopeptidase domain 21 ADAM21 8747 NM_003813 0006508 // proteolysis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207666_x_at NM_021014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021014.1 /DEF=Homo sapiens synovial sarcoma, X breakpoint 3 (SSX3), mRNA. /FEA=mRNA /GEN=SSX3 /PROD=synovial sarcoma, X breakpoint 3 /DB_XREF=gi:10337600 /UG=Hs.178749 synovial sarcoma, X breakpoint 3 /FL=gb:NM_021014.1 gb:U90840.1 NM_021014 synovial sarcoma, X breakpoint 3 SSX3 10214 NM_021014 /// NM_175711 /// XM_005272579 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 207667_s_at NM_002756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002756.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3), mRNA. /FEA=mRNA /GEN=MAP2K3 /PROD=mitogen-activated protein kinase kinase 3 /DB_XREF=gi:4506098 /UG=Hs.180533 mitogen-activated protein kinase kinase 3 /FL=gb:NM_002756.1 gb:L36719.1 NM_002756 dual specificity mitogen-activated protein kinase kinase 3-like /// mitogen-activated protein kinase kinase 3 LOC100996792 /// MAP2K3 5606 /// 100996792 NM_002756 /// NM_145109 /// NM_145110 /// XM_003846747 /// XM_005256721 /// XM_005256722 /// XM_005256723 /// XR_429863 /// XR_429864 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 207668_x_at NM_005742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005742.1 /DEF=Homo sapiens protein disulfide isomerase-related protein (P5), mRNA. /FEA=mRNA /GEN=P5 /PROD=protein disulfide isomerase-related protein /DB_XREF=gi:5031972 /UG=Hs.182429 protein disulfide isomerase-related protein /FL=gb:D49489.1 gb:NM_005742.1 NM_005742 protein disulfide isomerase family A, member 6 PDIA6 10130 NM_001282704 /// NM_001282705 /// NM_001282706 /// NM_001282707 /// NM_005742 /// XM_005246145 /// XM_006711856 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043277 // apoptotic cell clearance // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay 207669_at NM_002282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002282.1 /DEF=Homo sapiens keratin, hair, basic, 3 (KRTHB3), mRNA. /FEA=mRNA /GEN=KRTHB3 /PROD=keratin, hair, basic, 3 /DB_XREF=gi:4504932 /UG=Hs.182506 keratin, hair, basic, 3 /FL=gb:NM_002282.1 NM_002282 keratin 83 KRT83 3889 NM_002282 /// XM_005268864 /// XM_005275721 /// XM_006709960 0007568 // aging // inferred from direct assay /// 0008544 // epidermis development // traceable author statement /// 0042633 // hair cycle // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207670_at NM_002283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002283.1 /DEF=Homo sapiens keratin, hair, basic, 5 (KRTHB5), mRNA. /FEA=mRNA /GEN=KRTHB5 /PROD=keratin, hair, basic, 5 /DB_XREF=gi:4504934 /UG=Hs.182507 keratin, hair, basic, 5 /FL=gb:NM_002283.1 NM_002283 keratin 85 KRT85 3891 NM_002283 /// XM_005268865 0008544 // epidermis development // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207671_s_at NM_004183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004183.1 /DEF=Homo sapiens vitelliform macular dystrophy (Best disease, bestrophin) (VMD2), mRNA. /FEA=mRNA /GEN=VMD2 /PROD=vitelliform macular dystrophy (Best disease,bestrophin) /DB_XREF=gi:4759309 /UG=Hs.182771 vitelliform macular dystrophy (Best disease, bestrophin) /FL=gb:AF057169.1 gb:AF073501.1 gb:NM_004183.1 NM_004183 bestrophin 1 BEST1 7439 NM_001139443 /// NM_004183 /// XM_005274210 /// XM_005274213 /// XM_005274215 /// XM_005274216 /// XM_005274217 /// XM_005274218 /// XM_005274219 /// XM_005274221 /// XM_006718676 /// XM_006718677 /// XM_006718678 /// XM_006718679 /// XM_006718680 /// XR_247211 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0030321 // transepithelial chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0034707 // chloride channel complex // inferred from electronic annotation 0005254 // chloride channel activity // inferred from direct assay 207672_at NM_002920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002920.1 /DEF=Homo sapiens regulatory factor X, 4 (influences HLA class II expression) (RFX4), mRNA. /FEA=mRNA /GEN=RFX4 /PROD=regulatory factor X, 4 (influences HLA class IIexpression) /DB_XREF=gi:4506496 /UG=Hs.183009 regulatory factor X, 4 (influences HLA class II expression) /FL=gb:M69296.1 gb:NM_002920.1 NM_002920 regulatory factor X, 4 (influences HLA class II expression) RFX4 5992 NM_001206691 /// NM_002920 /// NM_032491 /// NM_213594 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0021516 // dorsal spinal cord development // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030284 // estrogen receptor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207673_at NM_004646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004646.1 /DEF=Homo sapiens nephrosis 1, congenital, Finnish type (nephrin) (NPHS1), mRNA. /FEA=mRNA /GEN=NPHS1 /PROD=nephrin /DB_XREF=gi:4758821 /UG=Hs.190311 nephrosis 1, congenital, Finnish type (nephrin) /FL=gb:AF190637.1 gb:AF035835.1 gb:NM_004646.1 NM_004646 nephrosis 1, congenital, Finnish type (nephrin) NPHS1 4868 NM_004646 /// XM_005258961 0000165 // MAPK cascade // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0032836 // glomerular basement membrane development // inferred from expression pattern /// 0044062 // regulation of excretion // inferred from electronic annotation /// 0072015 // glomerular visceral epithelial cell development // inferred from expression pattern 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from electronic annotation 207674_at NM_002000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002000.1 /DEF=Homo sapiens Fc fragment of IgA, receptor for (FCAR), mRNA. /FEA=mRNA /GEN=FCAR /PROD=Fc fragment of IgA, receptor for /DB_XREF=gi:4503672 /UG=Hs.193122 Fc fragment of IgA, receptor for /FL=gb:D87855.1 gb:D87861.1 gb:NM_002000.1 NM_002000 Fc fragment of IgA, receptor for FCAR 2204 NM_002000 /// NM_133269 /// NM_133271 /// NM_133272 /// NM_133273 /// NM_133274 /// NM_133277 /// NM_133278 /// NM_133279 /// NM_133280 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019862 // IgA binding // inferred from electronic annotation 207675_x_at NM_003976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003976.1 /DEF=Homo sapiens artemin (ARTN), mRNA. /FEA=mRNA /GEN=ARTN /PROD=neurotrophic factor artemin precursor /DB_XREF=gi:4502244 /UG=Hs.194689 artemin /FL=gb:AF109401.1 gb:NM_003976.1 NM_003976 artemin ARTN 9048 NM_001136215 /// NM_003976 /// NM_057090 /// NM_057091 /// NM_057160 /// XM_006711023 /// XM_006711024 0007165 // signal transduction // traceable author statement /// 0007405 // neuroblast proliferation // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0097021 // lymphocyte migration into lymphoid organs // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 207676_at NM_004852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004852.1 /DEF=Homo sapiens one cut domain, family member 2 (ONECUT2), mRNA. /FEA=mRNA /GEN=ONECUT2 /PROD=one cut domain, family member 2 /DB_XREF=gi:4758847 /UG=Hs.194725 one cut domain, family member 2 /FL=gb:NM_004852.1 NM_004852 one cut homeobox 2 ONECUT2 9480 NM_004852 0001889 // liver development // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207677_s_at NM_013416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013416.1 /DEF=Homo sapiens neutrophil cytosolic factor 4 (40kD) (NCF4), transcript variant 2, mRNA. /FEA=mRNA /GEN=NCF4 /PROD=neutrophil cytosolic factor 4 (40kD), isoform 2 /DB_XREF=gi:7382492 /UG=Hs.196352 neutrophil cytosolic factor 4 (40kD) /FL=gb:BC002798.1 gb:AB025219.1 gb:NM_013416.1 NM_013416 neutrophil cytosolic factor 4, 40kDa NCF4 4689 NM_000631 /// NM_013416 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from mutant phenotype /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032010 // phagolysosome // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from mutant phenotype /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // traceable author statement 207678_s_at NM_007017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007017.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 30 (SOX30), mRNA. /FEA=mRNA /GEN=SOX30 /PROD=SRY (sex determining region Y)-box 30 /DB_XREF=gi:5902111 /UG=Hs.197805 SRY (sex determining region Y)-box 30 /FL=gb:AB022441.1 gb:NM_007017.1 NM_007017 SRY (sex determining region Y)-box 30 SOX30 11063 NM_007017 /// NM_178424 /// XM_005265802 /// XM_005265803 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0031960 // response to corticosteroid // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 207679_at NM_000438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000438.2 /DEF=Homo sapiens paired box gene 3 (Waardenburg syndrome 1) (PAX3), transcript variant PAX3A, mRNA. /FEA=mRNA /GEN=PAX3 /PROD=paired box gene 3, isoform PAX3A /DB_XREF=gi:6654637 /UG=Hs.198 paired box gene 3 (Waardenburg syndrome 1) /FL=gb:NM_000438.2 NM_000438 paired box 3 PAX3 5077 NM_000438 /// NM_001127366 /// NM_013942 /// NM_181457 /// NM_181458 /// NM_181459 /// NM_181460 /// NM_181461 /// XM_006712559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 207680_x_at NM_013942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013942.1 /DEF=Homo sapiens paired box gene 3 (Waardenburg syndrome 1) (PAX3), transcript variant PAX3B, mRNA. /FEA=mRNA /GEN=PAX3 /PROD=paired box gene 3, isoform PAX3B /DB_XREF=gi:7524355 /UG=Hs.198 paired box gene 3 (Waardenburg syndrome 1) /FL=gb:NM_013942.1 NM_013942 paired box 3 PAX3 5077 NM_000438 /// NM_001127366 /// NM_013942 /// NM_181457 /// NM_181458 /// NM_181459 /// NM_181460 /// NM_181461 /// XM_006712559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 207681_at NM_001504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001504.1 /DEF=Homo sapiens G protein-coupled receptor 9 (GPR9), mRNA. /FEA=mRNA /GEN=GPR9 /PROD=G protein-coupled receptor 9 /DB_XREF=gi:4504098 /UG=Hs.198252 G protein-coupled receptor 9 /FL=gb:NM_001504.1 NM_001504 chemokine (C-X-C motif) receptor 3 CXCR3 2833 NM_001142797 /// NM_001504 /// XM_005262256 /// XM_005262257 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002685 // regulation of leukocyte migration // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010818 // T cell chemotaxis // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0071954 // chemokine (C-C motif) ligand 11 production // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation /// 0019956 // chemokine binding // inferred from physical interaction /// 0019958 // C-X-C chemokine binding // inferred from direct assay 207682_s_at NM_005355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005355.2 /DEF=Homo sapiens kinesin-like 3 (KNSL3), transcript variant 2, mRNA. /FEA=mRNA /GEN=KNSL3 /PROD=kinesin-like 3 isoform 2 /DB_XREF=gi:13699827 /UG=Hs.198256 kinesin-like 3 /FL=gb:NM_005355.2 NM_005355 kinesin family member 25 KIF25 3834 NM_005355 /// NM_030615 /// XM_006715473 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 207683_at NM_003593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003593.1 /DEF=Homo sapiens winged-helix nude (WHN), mRNA. /FEA=mRNA /GEN=WHN /PROD=winged-helix nude /DB_XREF=gi:4507918 /UG=Hs.198313 winged-helix nude /FL=gb:NM_003593.1 NM_003593 forkhead box N1 FOXN1 8456 NM_003593 /// XM_005258046 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006952 // defense response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009790 // embryo development // /// 0009887 // organ morphogenesis // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0035878 // nail development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207684_at NM_004608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004608.1 /DEF=Homo sapiens T-box 6 (TBX6), mRNA. /FEA=mRNA /GEN=TBX6 /PROD=T-box 6 /DB_XREF=gi:4759213 /UG=Hs.198301 T-box 6 /FL=gb:NM_004608.1 NM_004608 T-box 6 TBX6 6911 NM_004608 /// NM_080758 /// XM_005255523 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 207685_at NM_004076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004076.3 /DEF=Homo sapiens crystallin, beta B3 (CRYBB3), mRNA. /FEA=mRNA /GEN=CRYBB3 /PROD=crystallin, beta B3 /DB_XREF=gi:12056466 /UG=Hs.198968 crystallin, beta B3 /FL=gb:NM_004076.3 NM_004076 crystallin, beta B3 CRYBB3 1417 NM_004076 0007601 // visual perception // traceable author statement 0005212 // structural constituent of eye lens // inferred from electronic annotation 207686_s_at NM_001228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001228.1 /DEF=Homo sapiens caspase 8, apoptosis-related cysteine protease (CASP8), mRNA. /FEA=mRNA /GEN=CASP8 /PROD=caspase 8, apoptosis-related cysteine protease /DB_XREF=gi:4502582 /UG=Hs.19949 caspase 8, apoptosis-related cysteine protease /FL=gb:U60520.1 gb:NM_001228.1 NM_001228 caspase 8, apoptosis-related cysteine peptidase CASP8 841 NM_001080124 /// NM_001080125 /// NM_001228 /// NM_033355 /// NM_033356 /// NM_033357 /// NM_033358 /// NR_111983 /// XM_005246885 /// XM_005246886 /// XM_005246887 /// XM_005246888 /// XM_005246889 /// XM_005246890 /// XM_005246891 /// XM_005246892 /// XM_005246893 /// XM_005246894 /// XM_005246895 /// XM_005246896 /// XM_006712789 /// XM_006712790 /// XM_006712791 /// XM_006712792 /// XM_006712793 /// XR_241323 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // not recorded /// 0009409 // response to cold // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030101 // natural killer cell activation // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0036462 // TRAIL-activated apoptotic signaling pathway // inferred from direct assay /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype /// 0060715 // syncytiotrophoblast cell differentiation involved in labyrinthine layer development // traceable author statement /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2001233 // regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0030690 // Noc1p-Noc2p complex // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 207687_at NM_005538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005538.1 /DEF=Homo sapiens inhibin, beta C (INHBC), mRNA. /FEA=mRNA /GEN=INHBC /PROD=inhibin beta C subunit precursor /DB_XREF=gi:5031794 /UG=Hs.199538 inhibin, beta C /FL=gb:NM_005538.1 NM_005538 inhibin, beta C INHBC 3626 NM_005538 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005160 // transforming growth factor beta receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 207688_s_at NM_005538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005538.1 /DEF=Homo sapiens inhibin, beta C (INHBC), mRNA. /FEA=mRNA /GEN=INHBC /PROD=inhibin beta C subunit precursor /DB_XREF=gi:5031794 /UG=Hs.199538 inhibin, beta C /FL=gb:NM_005538.1 NM_005538 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005160 // transforming growth factor beta receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 207689_at NM_005995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005995.1 /DEF=Homo sapiens T-box 10 (TBX10) mRNA. /FEA=mRNA /GEN=TBX10 /PROD=T-box 10 /DB_XREF=gi:5174708 /UG=Hs.203847 T-box 10 /FL=gb:NM_005995.1 NM_005995 T-box 10 TBX10 347853 NM_005995 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 207690_at NM_006492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006492.1 /DEF=Homo sapiens aristaless-like homeobox 3 (ALX3), mRNA. /FEA=mRNA /GEN=ALX3 /PROD=aristaless-like homeobox 3 /DB_XREF=gi:5729727 /UG=Hs.204039 aristaless-like homeobox 3 /FL=gb:AF008203.1 gb:NM_006492.1 NM_006492 ALX homeobox 3 ALX3 257 NM_006492 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207691_x_at NM_001776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001776.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), mRNA. /FEA=mRNA /GEN=ENTPD1 /PROD=ectonucleoside triphosphate diphosphohydrolase1 /DB_XREF=gi:4502666 /UG=Hs.205353 ectonucleoside triphosphate diphosphohydrolase 1 /FL=gb:NM_001776.1 NM_001776 ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 953 NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation 0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207692_s_at NM_001135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001135.1 /DEF=Homo sapiens aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) (AGC1), transcript variant 1, mRNA. /FEA=mRNA /GEN=AGC1 /PROD=aggrecan 1, isoform 1 precursor /DB_XREF=gi:4501990 /UG=Hs.2159 aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) /FL=gb:M55172.1 gb:NM_001135.1 NM_001135 aggrecan ACAN 176 NM_001135 /// NM_013227 /// XM_006720419 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030166 // proteoglycan biosynthetic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207693_at NM_000726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000726.1 /DEF=Homo sapiens calcium channel, voltage-dependent, beta 4 subunit (CACNB4), mRNA. /FEA=mRNA /GEN=CACNB4 /PROD=calcium channel, voltage-dependent, beta 4subunit /DB_XREF=gi:4502536 /UG=Hs.21903 calcium channel, voltage-dependent, beta 4 subunit /FL=gb:U95020.1 gb:NM_000726.1 NM_000726 calcium channel, voltage-dependent, beta 4 subunit CACNB4 785 NM_000726 /// NM_001005746 /// NM_001005747 /// NM_001145798 /// XM_005246838 /// XM_006712731 /// XM_006712732 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046058 // cAMP metabolic process // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050877 // neurological system process // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // traceable author statement /// 0045202 // synapse // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation 207694_at NM_000307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000307.1 /DEF=Homo sapiens POU domain, class 3, transcription factor 4 (POU3F4), mRNA. /FEA=mRNA /GEN=POU3F4 /PROD=POU domain, class 3, transcription factor 4 /DB_XREF=gi:4505962 /UG=Hs.2229 POU domain, class 3, transcription factor 4 /FL=gb:NM_000307.1 NM_000307 POU class 3 homeobox 4 POU3F4 5456 NM_000307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207695_s_at NM_001555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001555.1 /DEF=Homo sapiens immunoglobulin superfamily, member 1 (IGSF1), mRNA. /FEA=mRNA /GEN=IGSF1 /PROD=immunoglobulin superfamily, member 1 /DB_XREF=gi:4504624 /UG=Hs.22111 immunoglobulin superfamily, member 1 /FL=gb:NM_001555.1 NM_001555 immunoglobulin superfamily, member 1 IGSF1 3547 NM_001170961 /// NM_001170962 /// NM_001170963 /// NM_001555 /// NM_205833 /// XM_006724755 /// XM_006724756 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0034711 // inhibin binding // inferred from direct assay 207696_at NM_006581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006581.1 /DEF=Homo sapiens fucosyltransferase 9 (alpha (1,3) fucosyltransferase) (FUT9), mRNA. /FEA=mRNA /GEN=FUT9 /PROD=fucosyltransferase 9 (alpha (1,3)fucosyltransferase) /DB_XREF=gi:5729831 /UG=Hs.225945 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) /FL=gb:AB023021.1 gb:NM_006581.1 NM_006581 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) FUT9 10690 NM_006581 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017083 // 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 207697_x_at NM_005874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005874.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), mRNA. /FEA=mRNA /GEN=LILRB2 /PROD=leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains), member 2 /DB_XREF=gi:5031910 /UG=Hs.22405 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 /FL=gb:AF025528.1 gb:NM_005874.1 NM_005874 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 LILRB2 10288 NM_001080978 /// NM_001278403 /// NM_001278404 /// NM_001278405 /// NM_001278406 /// NM_005874 /// NR_103521 /// XM_006722966 /// XM_006722967 /// XM_006722968 /// XM_006722969 /// XM_006722970 /// XM_006726139 /// XM_006726140 /// XM_006726141 /// XM_006726142 /// XM_006726143 /// XM_006726170 /// XM_006726237 /// XM_006726238 /// XM_006726239 /// XM_006726240 /// XM_006726241 /// XM_006726242 /// XM_006726243 /// XM_006726244 /// XM_006726245 /// XR_430186 /// XR_431049 /// XR_431085 0002376 // immune system process // inferred from electronic annotation /// 0002578 // negative regulation of antigen processing and presentation // inferred from direct assay /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from mutant phenotype /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0032755 // positive regulation of interleukin-6 production // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from mutant phenotype /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2001198 // regulation of dendritic cell differentiation // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from physical interaction /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0032396 // inhibitory MHC class I receptor activity // inferred from direct assay /// 0032396 // inhibitory MHC class I receptor activity // inferred from mutant phenotype /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 207698_at NM_014356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014356.1 /DEF=Homo sapiens HGC6.2 protein (HGC6.2), mRNA. /FEA=mRNA /GEN=HGC6.2 /PROD=HGC6.2 protein /DB_XREF=gi:7657157 /UG=Hs.225964 HGC6.2 protein /FL=gb:AB016901.1 gb:NM_014356.1 NM_014356 chromosome 6 open reading frame 123 C6orf123 26238 NM_014356 /// NR_026773 207699_at NM_014894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014894.1 /DEF=Homo sapiens KIAA1056 protein (KIAA1056), mRNA. /FEA=mRNA /GEN=KIAA1056 /PROD=KIAA1056 protein /DB_XREF=gi:7662465 /UG=Hs.225975 KIAA1056 protein /FL=gb:AB028979.1 gb:NM_014894.1 NM_014894 zinc finger homeobox 2 ZFHX2 85446 NM_033400 /// XM_005268134 /// XM_005268135 /// XM_006720282 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207700_s_at NM_006534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006534.1 /DEF=Homo sapiens nuclear receptor coactivator 3 (NCOA3), mRNA. /FEA=mRNA /GEN=NCOA3 /PROD=nuclear receptor coactivator 3 /DB_XREF=gi:5729725 /UG=Hs.225977 nuclear receptor coactivator 3 /FL=gb:AF036892.1 gb:NM_006534.1 NM_006534 nuclear receptor coactivator 3 NCOA3 8202 NM_001174087 /// NM_001174088 /// NM_006534 /// NM_181659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035624 // receptor transactivation // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 207701_at NM_015372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015372.1 /DEF=Homo sapiens hypothetical protein (HSN44A4A), mRNA. /FEA=mRNA /GEN=HSN44A4A /PROD=hypothetical protein /DB_XREF=gi:7661723 /UG=Hs.225989 hypothetical protein /FL=gb:NM_015372.1 NM_015372 chromosome 22 open reading frame 24 C22orf24 25775 NM_015372 /// XM_005261497 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207702_s_at NM_012301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012301.1 /DEF=Homo sapiens atrophin-1 interacting protein 1; activin receptor interacting protein 1 (KIAA0705), mRNA. /FEA=mRNA /GEN=KIAA0705 /PROD=atrophin-1 interacting protein 1; activinreceptor interacting protein 1 /DB_XREF=gi:6912461 /UG=Hs.22599 atrophin-1 interacting protein 1; activin receptor interacting protein 1 /FL=gb:AF038563.1 gb:NM_012301.1 NM_012301 membrane associated guanylate kinase, WW and PDZ domain containing 2 MAGI2 9863 NM_012301 /// XM_005250725 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0003402 // planar cell polarity pathway involved in axis elongation // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from sequence or structural similarity /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from sequence or structural similarity /// 0070699 // type II activin receptor binding // inferred from sequence or structural similarity 207703_at NM_014893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014893.1 /DEF=Homo sapiens KIAA0951 protein (KIAA0951), mRNA. /FEA=mRNA /GEN=KIAA0951 /PROD=KIAA0951 protein /DB_XREF=gi:7662399 /UG=Hs.227327 KIAA0951 protein /FL=gb:AB023168.1 gb:NM_014893.1 NM_014893 neuroligin 4, Y-linked NLGN4Y 22829 NM_001164238 /// NM_001206850 /// NM_014893 /// NR_028319 /// NR_046355 /// XM_006724874 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007416 // synapse assembly // not recorded /// 0007612 // learning // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0035176 // social behavior // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0009986 // cell surface // not recorded /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // not recorded /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // not recorded /// 0050839 // cell adhesion molecule binding // traceable author statement 207704_s_at NM_003644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003644.1 /DEF=Homo sapiens growth arrest-specific 7 (GAS7), transcript variant a, mRNA. /FEA=mRNA /GEN=GAS7 /PROD=growth arrest-specific 7 isoform a /DB_XREF=gi:4503920 /UG=Hs.226133 growth arrest-specific 7 /FL=gb:NM_003644.1 NM_003644 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 207705_s_at NM_025176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025176.1 /DEF=Homo sapiens KIAA0980 protein (KIAA0980), mRNA. /FEA=mRNA /GEN=KIAA0980 /PROD=hypothetical protein FLJ11792 /DB_XREF=gi:13378150 /UG=Hs.227743 KIAA0980 protein /FL=gb:NM_025176.1 NM_025176 ninein-like NINL 22981 NM_025176 /// XM_005260678 /// XM_005260679 /// XM_005260680 /// XM_006723552 /// XM_006723553 /// XM_006723554 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207706_at NM_007123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007123.1 /DEF=Homo sapiens Usher syndrome 2A (autosomal recessive, mild) (USH2A), mRNA. /FEA=mRNA /GEN=USH2A /PROD=Usher syndrome type IIa protein /DB_XREF=gi:6005935 /UG=Hs.232072 Usher syndrome 2A (autosomal recessive, mild) /FL=gb:AF055580.1 gb:NM_007123.1 NM_007123 Usher syndrome 2A (autosomal recessive, mild) USH2A 7399 NM_007123 /// NM_206933 0007601 // visual perception // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0035315 // hair cell differentiation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0060113 // inner ear receptor cell differentiation // inferred from sequence or structural similarity 0002142 // stereocilia ankle link complex // inferred from sequence or structural similarity /// 0005576 // extracellular region // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0032421 // stereocilium bundle // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0060171 // stereocilium membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0017022 // myosin binding // inferred from sequence or structural similarity 207707_s_at NM_030673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030673.1 /DEF=Homo sapiens SEC13 (S. cerevisiae)-like 1 (SEC13L1), mRNA. /FEA=mRNA /GEN=SEC13L1 /PROD=SEC13 (S. cerevisiae)-like 1 /DB_XREF=gi:13491163 /UG=Hs.227949 SEC13 (S. cerevisiae)-like 1 /FL=gb:BC002634.1 gb:NM_030673.1 NM_030673 SEC13 homolog (S. cerevisiae) SEC13 6396 NM_001136026 /// NM_001136232 /// NM_001278946 /// NM_030673 /// NM_183352 /// XM_005265377 /// XM_005265378 /// XM_005265379 /// XM_006713286 /// XM_006713287 /// XM_006713288 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 207708_at NM_021628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021628.1 /DEF=Homo sapiens arachidonate lipoxygenase 3 (ALOXE3), mRNA. /FEA=mRNA /GEN=ALOXE3 /PROD=arachidonate lipoxygenase 3 /DB_XREF=gi:11055995 /UG=Hs.232770 arachidonate lipoxygenase 3 /FL=gb:AF182218.1 gb:NM_021628.1 NM_021628 arachidonate lipoxygenase 3 ALOXE3 59344 NM_001165960 /// NM_021628 /// XM_005256745 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // inferred from direct assay /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0043651 // linoleic acid metabolic process // inferred from direct assay /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0046513 // ceramide biosynthetic process // inferred from sequence or structural similarity /// 0051122 // hepoxilin biosynthetic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051120 // hepoxilin A3 synthase activity // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation 207709_at NM_006252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006252.1 /DEF=Homo sapiens protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2), mRNA. /FEA=mRNA /GEN=PRKAA2 /PROD=protein kinase, AMP-activated, alpha 2 catalyticsubunit /DB_XREF=gi:5453965 /UG=Hs.2329 protein kinase, AMP-activated, alpha 2 catalytic subunit /FL=gb:NM_006252.1 gb:U06454.1 NM_006252 protein kinase, AMP-activated, alpha 2 catalytic subunit PRKAA2 5563 NM_006252 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from sequence or structural similarity /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from sequence or structural similarity /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045821 // positive regulation of glycolytic process // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004679 // AMP-activated protein kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035174 // histone serine kinase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047322 // [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity // inferred from electronic annotation /// 0050405 // [acetyl-CoA carboxylase] kinase activity // inferred from electronic annotation 207710_at NM_014357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014357.1 /DEF=Homo sapiens skin-specific protein (XP5), mRNA. /FEA=mRNA /GEN=XP5 /PROD=skin-specific protein /DB_XREF=gi:7657684 /UG=Hs.234766 skin-specific protein /FL=gb:AF005080.1 gb:NM_014357.1 NM_014357 late cornified envelope 2B LCE2B 26239 NM_014357 0008544 // epidermis development // non-traceable author statement /// 0031424 // keratinization // inferred from electronic annotation 207711_at NM_015377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015377.1 /DEF=Homo sapiens KIAA0889 protein (KIAA0889), mRNA. /FEA=mRNA /GEN=KIAA0889 /PROD=KIAA0889 protein /DB_XREF=gi:7662359 /UG=Hs.234791 KIAA0889 protein /FL=gb:AB020696.1 gb:NM_015377.1 NM_015377 suppressor of glucose, autophagy associated 1 SOGA1 140710 NM_080627 /// NM_152257 /// NM_199181 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 207712_at NM_001187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001187.1 /DEF=Homo sapiens B melanoma antigen (BAGE), mRNA. /FEA=mRNA /GEN=BAGE /PROD=B melanoma antigen /DB_XREF=gi:4557346 /UG=Hs.2355 B melanoma antigen /FL=gb:NM_001187.1 gb:U19180.1 NM_001187 B melanoma antigen BAGE 574 NM_001187 0005576 // extracellular region // inferred from electronic annotation 207713_s_at NM_006462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006462.1 /DEF=Homo sapiens HBV associated factor (XAP4), mRNA. /FEA=mRNA /GEN=XAP4 /PROD=HBV associated factor /DB_XREF=gi:5454167 /UG=Hs.247280 HBV associated factor /FL=gb:NM_006462.1 NM_006462 RanBP-type and C3HC4-type zinc finger containing 1 RBCK1 10616 NM_006462 /// NM_031227 /// NM_031228 /// NM_031229 /// XM_005260645 /// XM_005260646 /// XM_005260649 /// XR_430266 /// XR_430267 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097039 // protein linear polyubiquitination // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0071797 // LUBAC complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207714_s_at NM_004353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004353.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1 (SERPINH1), mRNA. /FEA=mRNA /GEN=SERPINH1 /PROD=serine (or cysteine) proteinase inhibitor, cladeH (heat shock protein 47), member 1 /DB_XREF=gi:4757923 /UG=Hs.241579 serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1 /FL=gb:NM_004353.1 NM_004353 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) SERPINH1 871 NM_001207014 /// NM_001235 /// XM_006718727 /// XM_006718728 /// XM_006718729 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 207715_at NM_005210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005210.2 /DEF=Homo sapiens crystallin, gamma B (CRYGB), mRNA. /FEA=mRNA /GEN=CRYGB /PROD=crystallin, gamma B /DB_XREF=gi:13376999 /UG=Hs.248102 crystallin, gamma B /FL=gb:NM_005210.2 NM_005210 crystallin, gamma B CRYGB 1419 NM_005210 0001654 // eye development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007601 // visual perception // non-traceable author statement /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070309 // lens fiber cell morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005212 // structural constituent of eye lens // non-traceable author statement 207716_at NM_006771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006771.2 /DEF=Homo sapiens keratin, hair, acidic, 8 (KRTHA8), mRNA. /FEA=mRNA /GEN=KRTHA8 /PROD=type I hair keratin 8 /DB_XREF=gi:11641409 /UG=Hs.248188 keratin, hair, acidic, 8 /FL=gb:NM_006771.2 NM_006771 keratin 38 KRT38 8687 NM_006771 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207717_s_at NM_004572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004572.1 /DEF=Homo sapiens plakophilin 2 (PKP2), mRNA. /FEA=mRNA /GEN=PKP2 /PROD=plakophilin 2 /DB_XREF=gi:4758931 /UG=Hs.25051 plakophilin 2 /FL=gb:NM_004572.1 NM_004572 plakophilin 2 PKP2 5318 NM_001005242 /// NM_004572 0002159 // desmosome assembly // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0016264 // gap junction assembly // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0034334 // adherens junction maintenance // inferred from sequence or structural similarity /// 0045110 // intermediate filament bundle assembly // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086019 // cell-cell signaling involved in cardiac conduction // inferred from mutant phenotype /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000810 // regulation of tight junction assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from direct assay /// 0030057 // desmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // non-traceable author statement 0005080 // protein kinase C binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0019215 // intermediate filament binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from sequence or structural similarity 207718_x_at NM_000764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000764.1 /DEF=Homo sapiens cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7 (CYP2A7), transcript variant 1, mRNA. /FEA=mRNA /GEN=CYP2A7 /PROD=cytochrome P450, subfamily IIA(phenobarbital-inducible), polypeptide 7, isoform 1 /DB_XREF=gi:4503216 /UG=Hs.250615 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7 /FL=gb:U22029.1 gb:M33317.1 gb:NM_000764.1 NM_000764 cytochrome P450, family 2, subfamily A, polypeptide 7 CYP2A7 1549 NM_000764 /// NM_030589 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207719_x_at NM_014812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014812.1 /DEF=Homo sapiens KIAA0470 gene product (KIAA0470), mRNA. /FEA=mRNA /GEN=KIAA0470 /PROD=KARP-1-binding protein /DB_XREF=gi:7662141 /UG=Hs.25132 KIAA0470 gene product /FL=gb:AB022657.1 gb:NM_014812.1 NM_014812 centrosomal protein 170kDa /// centrosomal protein 170kDa pseudogene 1 CEP170 /// CEP170P1 9859 /// 645455 NM_001042404 /// NM_001042405 /// NM_014812 /// NM_153243 /// NR_003135 /// XM_005273361 /// XM_006711843 /// XM_006711844 /// XM_006711845 /// XM_006711846 /// XM_006711847 /// XM_006711848 /// XM_006711849 /// XM_006711850 /// XM_006711851 /// XM_006711852 /// XM_006724974 /// XM_006724975 /// XM_006724976 /// XM_006724977 /// XM_006724978 /// XM_006724979 /// XM_006724980 /// XM_006724981 /// XM_006724982 /// XM_006724983 /// XM_006724984 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 207720_at NM_000427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000427.1 /DEF=Homo sapiens loricrin (LOR), mRNA. /FEA=mRNA /GEN=LOR /PROD=loricrin /DB_XREF=gi:4557724 /UG=Hs.251680 loricrin /FL=gb:M61120.1 gb:NM_000427.1 NM_000427 loricrin LOR 4014 NM_000427 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005198 // structural molecule activity // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay 207721_x_at NM_005340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005340.1 /DEF=Homo sapiens histidine triad nucleotide-binding protein (HINT), mRNA. /FEA=mRNA /GEN=HINT /PROD=histidine triad nucleotide-binding protein /DB_XREF=gi:4885412 /UG=Hs.256697 histidine triad nucleotide-binding protein /FL=gb:U51004.1 gb:NM_005340.1 NM_005340 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 /// NR_073488 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009154 // purine ribonucleotide catabolic process // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from direct assay 207722_s_at NM_017797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017797.1 /DEF=Homo sapiens BTB (POZ) domain containing 2 (BTBD2), mRNA. /FEA=mRNA /GEN=BTBD2 /PROD=BTB (POZ) domain containing 2 /DB_XREF=gi:8923361 /UG=Hs.25817 BTB (POZ) domain containing 2 /FL=gb:NM_017797.1 NM_017797 BTB (POZ) domain containing 2 BTBD2 55643 NM_017797 /// XM_005259593 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207723_s_at NM_002261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002261.1 /DEF=Homo sapiens killer cell lectin-like receptor subfamily C, member 3 (KLRC3), transcript variant NKG2-E, mRNA. /FEA=mRNA /GEN=KLRC3 /PROD=killer cell lectin-like receptor subfamily C,member 3 isoform NKG2-E /DB_XREF=gi:4504884 /UG=Hs.258850 killer cell lectin-like receptor subfamily C, member 3 /FL=gb:L14542.1 gb:NM_002261.1 NM_002261 killer cell lectin-like receptor subfamily C, member 3 KLRC3 3823 NM_002261 /// NM_007333 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 207724_s_at NM_014946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014946.2 /DEF=Homo sapiens spastic paraplegia 4 (autosomal dominant; spastin) (SPG4), mRNA. /FEA=mRNA /GEN=SPG4 /PROD=spastin /DB_XREF=gi:11875210 /UG=Hs.26334 spastic paraplegia 4 (autosomal dominant; spastin) /FL=gb:NM_014946.2 NM_014946 spastin SPAST 6683 NM_014946 /// NM_199436 /// XM_005264516 0001578 // microtubule bundle formation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from electronic annotation /// 0034214 // protein hexamerization // inferred from direct assay /// 0051013 // microtubule severing // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from physical interaction 207725_at NM_004575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004575.1 /DEF=Homo sapiens POU domain, class 4, transcription factor 2 (POU4F2), mRNA. /FEA=mRNA /GEN=POU4F2 /PROD=POU domain, class 4, transcription factor 2 /DB_XREF=gi:4758947 /UG=Hs.266 POU domain, class 4, transcription factor 2 /FL=gb:U06233.1 gb:NM_004575.1 NM_004575 POU class 4 homeobox 2 POU4F2 5458 NM_004575 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048675 // axon extension // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207726_at NM_004452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004452.1 /DEF=Homo sapiens estrogen-related receptor beta (ESRRB), mRNA. /FEA=mRNA /GEN=ESRRB /PROD=estrogen-related receptor beta /DB_XREF=gi:4758307 /UG=Hs.267665 estrogen-related receptor beta /FL=gb:NM_004452.1 NM_004452 estrogen-related receptor beta ESRRB 2103 NM_004452 /// XM_005267404 /// XM_006720077 /// XM_006720078 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0001834 // trophectodermal cell proliferation // inferred from electronic annotation /// 0001892 // embryonic placenta development // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207727_s_at NM_012222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012222.1 /DEF=Homo sapiens mutY (E. coli) homolog (MUTYH), mRNA. /FEA=mRNA /GEN=MUTYH /PROD=mutY (E. coli) homolog /DB_XREF=gi:6912519 /UG=Hs.271353 mutY (E. coli) homolog /FL=gb:AB032920.1 gb:AB032924.1 gb:NM_012222.1 NM_012222 mutY homolog MUTYH 4595 NM_001048171 /// NM_001048172 /// NM_001048173 /// NM_001048174 /// NM_001128425 /// NM_001293190 /// NM_001293191 /// NM_001293192 /// NM_001293195 /// NM_001293196 /// NM_012222 /// XM_005270880 /// XM_005270881 /// XM_005270884 /// XM_005270885 /// XM_006710648 /// XM_006710649 /// XM_006710650 /// XM_006710651 /// XM_006710652 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006298 // mismatch repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045007 // depurination // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0032406 // MutLbeta complex binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay /// 0032408 // MutSbeta complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 207728_at NM_018005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018005.1 /DEF=Homo sapiens hypothetical protein FLJ10139 (FLJ10139), mRNA. /FEA=mRNA /GEN=FLJ10139 /PROD=hypothetical protein FLJ10139 /DB_XREF=gi:8922245 /UG=Hs.272210 hypothetical protein FLJ10139 /FL=gb:NM_018005.1 NM_018005 activating transcription factor 7 interacting protein ATF7IP 55729 NM_001286514 /// NM_001286515 /// NM_018179 /// NM_181352 /// XM_005253424 /// XM_006719108 /// XM_006719109 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045898 // regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from electronic annotation 207729_at NM_016279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016279.1 /DEF=Homo sapiens cadherin 9, type 2 (T1-cadherin) (CDH9), mRNA. /FEA=mRNA /GEN=CDH9 /PROD=cadherin 9, type 2 /DB_XREF=gi:7705922 /UG=Hs.272212 cadherin 9, type 2 (T1-cadherin) /FL=gb:AB035302.1 gb:NM_016279.1 NM_016279 cadherin 9, type 2 (T1-cadherin) CDH9 1007 NM_016279 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207730_x_at NM_017932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017932.1 /DEF=Homo sapiens hypothetical protein FLJ20700 (FLJ20700), mRNA. /FEA=mRNA /GEN=FLJ20700 /PROD=hypothetical protein FLJ20700 /DB_XREF=gi:8923629 /UG=Hs.272222 hypothetical protein FLJ20700 /FL=gb:NM_017932.1 NM_017932 207731_at NM_020118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020118.1 /DEF=Homo sapiens hypothetical protein FLB3342 (FLB3342), mRNA. /FEA=mRNA /GEN=FLB3342 /PROD=hypothetical protein FLB3342 /DB_XREF=gi:9910219 /UG=Hs.272402 hypothetical protein FLB3342 /FL=gb:NM_020118.1 NM_020118 207732_s_at NM_021120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021120.1 /DEF=Homo sapiens discs, large (Drosophila) homolog 3 (neuroendocrine-dlg) (DLG3), mRNA. /FEA=mRNA /GEN=DLG3 /PROD=discs, large (Drosophila) homolog 3(neuroendocrine-dlg) /DB_XREF=gi:10863920 /UG=Hs.272438 discs, large (Drosophila) homolog 3 (neuroendocrine-dlg) /FL=gb:NM_021120.1 gb:U49089.1 NM_021120 discs, large homolog 3 (Drosophila) DLG3 1741 NM_001166278 /// NM_020730 /// NM_021120 /// XM_005262248 /// XM_006724625 /// XM_006724626 /// XM_006724627 /// XR_430518 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004385 // guanylate kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 207733_x_at NM_002784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002784.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 9 (PSG9), mRNA. /FEA=mRNA /GEN=PSG9 /PROD=pregnancy specific beta-1-glycoprotein 9 /DB_XREF=gi:4506166 /UG=Hs.272620 pregnancy specific beta-1-glycoprotein 9 /FL=gb:NM_002784.1 gb:U25987.1 NM_002784 pregnancy specific beta-1-glycoprotein 9 PSG9 5678 NM_002784 /// XM_005259074 /// XM_005259075 /// XM_005259076 /// XM_005259077 /// XM_005259078 /// XM_005259079 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 207734_at NM_017773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017773.1 /DEF=Homo sapiens hypothetical protein FLJ20340 (FLJ20340), mRNA. /FEA=mRNA /GEN=FLJ20340 /PROD=hypothetical protein FLJ20340 /DB_XREF=gi:8923315 /UG=Hs.272794 hypothetical protein FLJ20340 /FL=gb:NM_017773.1 NM_017773 lymphocyte transmembrane adaptor 1 LAX1 54900 NM_001136190 /// NM_001282878 /// NM_017773 /// XM_006711397 /// XM_006711398 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0046649 // lymphocyte activation // inferred from electronic annotation /// 0048305 // immunoglobulin secretion // inferred from electronic annotation /// 0050851 // antigen receptor-mediated signaling pathway // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from direct assay 207735_at NM_017831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017831.1 /DEF=Homo sapiens hypothetical protein FLJ20456 (FLJ20456), mRNA. /FEA=mRNA /GEN=FLJ20456 /PROD=hypothetical protein FLJ20456 /DB_XREF=gi:8923428 /UG=Hs.272800 hypothetical protein FLJ20456 /FL=gb:NM_017831.1 NM_017831 ring finger protein 125, E3 ubiquitin protein ligase RNF125 54941 NM_017831 0002376 // immune system process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207736_s_at NM_005425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005425.1 /DEF=Homo sapiens transition protein 2 (during histone to protamine replacement) (TNP2), mRNA. /FEA=mRNA /GEN=TNP2 /PROD=transition protein 2 (during histone toprotamine replacement) /DB_XREF=gi:4885634 /UG=Hs.2748 transition protein 2 (during histone to protamine replacement) /FL=gb:NM_005425.1 NM_005425 transition protein 2 (during histone to protamine replacement) TNP2 7142 NM_005425 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207737_at NM_021981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021981.1 /DEF=Homo sapiens pre-TNK cell associated protein (1D12A), mRNA. /FEA=mRNA /GEN=1D12A /PROD=pre-TNK cell associated protein /DB_XREF=gi:11415055 /UG=Hs.278 pre-TNK cell associated protein /FL=gb:NM_021981.1 gb:L17325.1 NM_021981 0006955 // immune response // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement 207738_s_at NM_013436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013436.1 /DEF=Homo sapiens NCK-associated protein 1 (NCKAP1), mRNA. /FEA=mRNA /GEN=NCKAP1 /PROD=NCK-associated protein 1 /DB_XREF=gi:7305302 /UG=Hs.278411 NCK-associated protein 1 /FL=gb:AB014509.1 gb:NM_013436.1 NM_013436 NCK-associated protein 1 NCKAP1 10787 NM_013436 /// NM_205842 /// XM_006712200 /// XM_006712201 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0008078 // mesodermal cell migration // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030950 // establishment or maintenance of actin cytoskeleton polarity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045175 // basal protein localization // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay 207739_s_at NM_001472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001472.1 /DEF=Homo sapiens G antigen 2 (GAGE2), mRNA. /FEA=mRNA /GEN=GAGE2 /PROD=G antigen 2 /DB_XREF=gi:4503878 /UG=Hs.278444 G antigen 2 /FL=gb:NM_001472.1 gb:U19143.1 NM_001472 G antigen 1 /// G antigen 12B /// G antigen 12C /// G antigen 12D /// G antigen 12E /// G antigen 12F /// G antigen 12G /// G antigen 12H /// G antigen 12I /// G antigen 12J /// G antigen 13 /// G antigen 2A /// G antigen 2B /// G antigen 2C /// G antigen 2D /// G antigen 2E /// G antigen 3 /// G antigen 4 /// G antigen 5 /// G antigen 6 /// G antigen 7 /// G antigen 8 GAGE1 /// GAGE12B /// GAGE12C /// GAGE12D /// GAGE12E /// GAGE12F /// GAGE12G /// GAGE12H /// GAGE12I /// GAGE12J /// GAGE13 /// GAGE2A /// GAGE2B /// GAGE2C /// GAGE2D /// GAGE2E /// GAGE3 /// GAGE4 /// GAGE5 /// GAGE6 /// GAGE7 /// GAGE8 2543 /// 2574 /// 2575 /// 2576 /// 2577 /// 2578 /// 2579 /// 26748 /// 26749 /// 645037 /// 645051 /// 645073 /// 729396 /// 729408 /// 729422 /// 729428 /// 729431 /// 729442 /// 729447 /// 100008586 /// 100101629 /// 100132399 NM_001040663 /// NM_001098405 /// NM_001098406 /// NM_001098407 /// NM_001098408 /// NM_001098409 /// NM_001098410 /// NM_001098411 /// NM_001098412 /// NM_001098418 /// NM_001127199 /// NM_001127200 /// NM_001127212 /// NM_001127345 /// NM_001468 /// NM_001472 /// NM_001474 /// NM_001475 /// NM_001476 /// NM_001477 /// NM_012196 /// NM_021123 /// NR_102272 /// XM_005272739 /// XM_005278009 0006968 // cellular defense response // traceable author statement 0005515 // protein binding // inferred from physical interaction 207740_s_at NM_012346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012346.1 /DEF=Homo sapiens nucleoporin 62kD (NUP62), mRNA. /FEA=mRNA /GEN=NUP62 /PROD=nucleoporin 62kD /DB_XREF=gi:6912543 /UG=Hs.278511 nucleoporin 62kD /FL=gb:NM_012346.1 NM_012346 nucleoporin 62kDa NUP62 23636 NM_001193357 /// NM_012346 /// NM_016553 /// NM_153718 /// NM_153719 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008645 // hexose transport // traceable author statement /// 0009755 // hormone-mediated signaling pathway // non-traceable author statement /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031074 // nucleocytoplasmic shuttling complex // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0046930 // pore complex // non-traceable author statement 0003682 // chromatin binding // non-traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from sequence or structural similarity /// 0051425 // PTB domain binding // inferred from electronic annotation 207741_x_at NM_003293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003293.2 /DEF=Homo sapiens tryptase, alpha (TPS1), mRNA. /FEA=mRNA /GEN=TPS1 /PROD=alpha tryptase I precursor /DB_XREF=gi:13699841 /UG=Hs.278528 tryptase, alpha /FL=gb:M30038.1 gb:NM_003293.2 NM_003293 tryptase alpha/beta 1 TPSAB1 7177 NM_003294 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207742_s_at NM_001489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001489.1 /DEF=Homo sapiens nuclear receptor subfamily 6, group A, member 1 (NR6A1), mRNA. /FEA=mRNA /GEN=NR6A1 /PROD=nuclear receptor subfamily 6, group A, member 1 /DB_XREF=gi:4503958 /UG=Hs.278599 nuclear receptor subfamily 6, group A, member 1 /FL=gb:U64876.1 gb:NM_001489.1 NM_001489 nuclear receptor subfamily 6, group A, member 1 NR6A1 2649 NM_001278546 /// NM_001489 /// NM_033334 /// NM_033335 /// XM_005251917 /// XM_005251918 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007276 // gamete generation // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 207743_at NM_014104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014104.1 /DEF=Homo sapiens PRO1880 protein (PRO1880), mRNA. /FEA=mRNA /GEN=PRO1880 /PROD=PRO1880 protein /DB_XREF=gi:7662620 /UG=Hs.278926 PRO1880 protein /FL=gb:AF118080.1 gb:NM_014104.1 NM_014104 207744_at NM_014124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014124.1 /DEF=Homo sapiens PRO0255 protein (PRO0255), mRNA. /FEA=mRNA /GEN=PRO0255 /PROD=PRO0255 protein /DB_XREF=gi:7662541 /UG=Hs.278935 PRO0255 protein /FL=gb:AF090909.1 gb:NM_014124.1 NM_014124 207745_at NM_016366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016366.1 /DEF=Homo sapiens calcium binding protein 2 (CABP2), mRNA. /FEA=mRNA /GEN=CABP2 /PROD=calcium binding protein 2 /DB_XREF=gi:7705311 /UG=Hs.278984 calcium binding protein 2 /FL=gb:AF169154.1 gb:NM_016366.1 NM_016366 calcium binding protein 2 CABP2 51475 NM_016366 /// NM_031204 /// XM_005274046 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207746_at NM_014125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014125.1 /DEF=Homo sapiens PRO0327 protein (PRO0327), mRNA. /FEA=mRNA /GEN=PRO0327 /PROD=PRO0327 protein /DB_XREF=gi:7662545 /UG=Hs.279812 PRO0327 protein /FL=gb:AF090919.1 gb:NM_014125.1 NM_014125 polymerase (DNA directed), theta POLQ 10721 NM_199420 /// XM_006713480 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from direct assay /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0043142 // single-stranded DNA-dependent ATPase activity // inferred from direct assay 207747_s_at NM_018110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018110.1 /DEF=Homo sapiens hypothetical protein FLJ10488 (FLJ10488), mRNA. /FEA=mRNA /GEN=FLJ10488 /PROD=hypothetical protein FLJ10488 /DB_XREF=gi:8922455 /UG=Hs.279832 hypothetical protein FLJ10488 /FL=gb:NM_018110.1 NM_018110 docking protein 4 DOK4 55715 NM_018110 /// XM_005256042 /// XM_005256043 0000165 // MAPK cascade // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 207748_at NM_014122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014122.1 /DEF=Homo sapiens PRO0245 protein (PRO0245), mRNA. /FEA=mRNA /GEN=PRO0245 /PROD=PRO0245 protein /DB_XREF=gi:7662537 /UG=Hs.279892 PRO0245 protein /FL=gb:AF090907.1 gb:NM_014122.1 NM_014122 deoxyuridine triphosphatase pseudogene 1 /// DUTP1 /// DUTP1 0046080 // dUTP metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 207749_s_at NM_002718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002718.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform (PPP2R3), mRNA. /FEA=mRNA /GEN=PPP2R3 /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit B (PR 72), alpha isoform and (PR 130), betaisoform /DB_XREF=gi:4506020 /UG=Hs.28219 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform /FL=gb:L12146.1 gb:NM_002718.1 NM_002718 protein phosphatase 2, regulatory subunit B'', alpha PPP2R3A 5523 NM_001190447 /// NM_002718 /// NM_181897 /// XM_006713686 0001754 // eye photoreceptor cell differentiation // inferred from genetic interaction /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007525 // somatic muscle development // inferred from genetic interaction /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 0061053 // somite development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred by curator /// 0090249 // regulation of cell motility involved in somitogenic axis elongation // inferred from genetic interaction /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207750_at NM_018510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018510.1 /DEF=Homo sapiens hypothetical protein PRO1866 (PRO1866), mRNA. /FEA=mRNA /GEN=PRO1866 /PROD=hypothetical protein PRO1866 /DB_XREF=gi:8924091 /UG=Hs.283031 hypothetical protein PRO1866 /FL=gb:AF119858.1 gb:NM_018510.1 NM_018510 epidermal growth factor receptor pathway substrate 15 pseudogene 1 /// EPS15P1 /// EPS15P1 207751_at NM_018544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018544.1 /DEF=Homo sapiens hypothetical protein PRO2949 (PRO2949), mRNA. /FEA=mRNA /GEN=PRO2949 /PROD=hypothetical protein PRO2949 /DB_XREF=gi:8924218 /UG=Hs.283045 hypothetical protein PRO2949 /FL=gb:AF119907.1 gb:NM_018544.1 NM_018544 uncharacterized protein PRO2949 PRO2949 55412 207752_x_at NM_005039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005039.1 /DEF=Homo sapiens proline-rich protein BstNI subfamily 1 (PRB1), mRNA. /FEA=mRNA /GEN=PRB1 /PROD=proline-rich protein BstNI subfamily 1 /DB_XREF=gi:4826937 /UG=Hs.283658 proline-rich protein BstNI subfamily 1 /FL=gb:K03204.1 gb:NM_005039.1 NM_005039 proline-rich protein BstNI subfamily 1 PRB1 5542 NM_005039 /// NM_199353 /// NM_199354 0005576 // extracellular region // inferred from electronic annotation 207753_at NM_020657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020657.1 /DEF=Homo sapiens zinc finger protein 304 (ZNF304), mRNA. /FEA=mRNA /GEN=ZNF304 /PROD=zinc finger protein 304 /DB_XREF=gi:10190695 /UG=Hs.287374 zinc finger protein 304 /FL=gb:NM_020657.1 NM_020657 zinc finger protein 304 ZNF304 57343 NM_001290318 /// NM_001290319 /// NM_020657 /// XM_005259090 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207754_at NM_007211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007211.1 /DEF=Homo sapiens carcinoma associated (HOJ-1), mRNA. /FEA=mRNA /GEN=HOJ-1 /PROD=carcinoma associated /DB_XREF=gi:6005777 /UG=Hs.28529 chromosome 12 open reading frame 2 /FL=gb:U82396.1 gb:NM_007211.1 NM_007211 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 RASSF8 11228 NM_001164746 /// NM_001164747 /// NM_001164748 /// NM_007211 /// XM_006719027 /// XM_006719028 0007165 // signal transduction // inferred from electronic annotation 207755_at NM_025017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025017.1 /DEF=Homo sapiens hypothetical protein FLJ13892 (FLJ13892), mRNA. /FEA=mRNA /GEN=FLJ13892 /PROD=hypothetical protein FLJ13892 /DB_XREF=gi:13376536 /UG=Hs.287608 hypothetical protein FLJ13892 /FL=gb:NM_025017.1 NM_025017 207756_at NM_025028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025028.1 /DEF=Homo sapiens hypothetical protein FLJ14310 (FLJ14310), mRNA. /FEA=mRNA /GEN=FLJ14310 /PROD=hypothetical protein FLJ14310 /DB_XREF=gi:13376549 /UG=Hs.287634 hypothetical protein FLJ14310 /FL=gb:NM_025028.1 NM_025028 207757_at NM_030613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030613.1 /DEF=Homo sapiens hypothetical protein FLJ21628 (FLJ21628), mRNA. /FEA=mRNA /GEN=FLJ21628 /PROD=hypothetical protein FLJ21628 /DB_XREF=gi:13449266 /UG=Hs.287674 hypothetical protein FLJ21628 /FL=gb:NM_030613.1 NM_030613 ZFP2 zinc finger protein ZFP2 80108 NM_030613 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 207758_at NM_025056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025056.1 /DEF=Homo sapiens hypothetical protein FLJ23185 (FLJ23185), mRNA. /FEA=mRNA /GEN=FLJ23185 /PROD=hypothetical protein FLJ23185 /DB_XREF=gi:13376588 /UG=Hs.287732 hypothetical protein FLJ23185 /FL=gb:NM_025056.1 NM_025056 207759_s_at NM_025068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025068.1 /DEF=Homo sapiens hypothetical protein FLJ13381 (FLJ13381), mRNA. /FEA=mRNA /GEN=FLJ13381 /PROD=hypothetical protein FLJ13381 /DB_XREF=gi:13376608 /UG=Hs.287988 hypothetical protein FLJ13381 /FL=gb:NM_025068.1 NM_025068 disrupted in schizophrenia 1 /// TSNAX-DISC1 readthrough (NMD candidate) DISC1 /// TSNAX-DISC1 27185 /// 100303453 NM_001012957 /// NM_001012958 /// NM_001012959 /// NM_001039383 /// NM_001164537 /// NM_001164538 /// NM_001164539 /// NM_001164540 /// NM_001164541 /// NM_001164542 /// NM_001164544 /// NM_001164545 /// NM_001164546 /// NM_001164547 /// NM_001164548 /// NM_001164549 /// NM_001164550 /// NM_001164551 /// NM_001164552 /// NM_001164553 /// NM_001164554 /// NM_001164555 /// NM_001164556 /// NM_018662 /// NR_028393 /// NR_028394 /// NR_028395 /// NR_028396 /// NR_028397 /// NR_028398 /// NR_028399 /// NR_028400 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from mutant phenotype /// 0002052 // positive regulation of neuroblast proliferation // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from genetic interaction /// 0031929 // TOR signaling // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0090128 // regulation of synapse maturation // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // traceable author statement /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207760_s_at NM_006312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006312.1 /DEF=Homo sapiens nuclear receptor co-repressor 2 (NCOR2), mRNA. /FEA=mRNA /GEN=NCOR2 /PROD=nuclear receptor co-repressor 2 /DB_XREF=gi:5454073 /UG=Hs.287994 nuclear receptor co-repressor 2 /FL=gb:AF113003.1 gb:NM_006312.1 NM_006312 nuclear receptor corepressor 2 NCOR2 9612 NM_001077261 /// NM_001206654 /// NM_006312 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0072365 // regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 207761_s_at NM_014033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014033.1 /DEF=Homo sapiens DKFZP586A0522 protein (DKFZP586A0522), mRNA. /FEA=mRNA /GEN=DKFZP586A0522 /PROD=DKFZP586A0522 protein /DB_XREF=gi:13378140 /UG=Hs.288771 DKFZP586A0522 protein /FL=gb:NM_014033.1 NM_014033 methyltransferase like 7A METTL7A 25840 NM_014033 /// XM_006719332 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0009877 // nodulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 207762_at NM_024492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024492.1 /DEF=Homo sapiens apolipoprotein (a) related gene C (APOARGC), mRNA. /FEA=mRNA /GEN=APOARGC /PROD=apolipoprotein (a) related gene C /DB_XREF=gi:13346501 /UG=Hs.289049 apolipoprotein (a) related gene C /FL=gb:NM_024492.1 gb:U19517.1 NM_024492 lipoprotein, Lp(a)-like 2, pseudogene LPAL2 80350 NM_024492 /// NM_145727 /// NR_028092 /// NR_028093 0005576 // extracellular region // inferred from electronic annotation 207763_at NM_002962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002962.1 /DEF=Homo sapiens S100 calcium-binding protein A5 (S100A5), mRNA. /FEA=mRNA /GEN=S100A5 /PROD=S100 calcium-binding protein A5 /DB_XREF=gi:4506766 /UG=Hs.2960 S100 calcium-binding protein A5 /FL=gb:NM_002962.1 NM_002962 S100 calcium binding protein A5 S100A5 6276 NM_002962 /// XM_005245429 /// XM_005245430 0005634 // nucleus // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207764_s_at NM_005734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005734.1 /DEF=Homo sapiens homeodomain-interacting protein kinase 3 (HIPK3), mRNA. /FEA=mRNA /GEN=HIPK3 /PROD=homeodomain-interacting protein kinase 3 /DB_XREF=gi:11386208 /UG=Hs.30148 homeodomain-interacting protein kinase 3 /FL=gb:NM_005734.1 gb:AF004849.1 NM_005734 homeodomain interacting protein kinase 3 HIPK3 10114 NM_001048200 /// NM_001278162 /// NM_001278163 /// NM_005734 /// XM_005252729 /// XM_006718120 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009299 // mRNA transcription // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 207765_s_at NM_025182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025182.1 /DEF=Homo sapiens hypothetical protein FLJ11560 (FLJ11560), mRNA. /FEA=mRNA /GEN=FLJ11560 /PROD=hypothetical protein FLJ11560 /DB_XREF=gi:13378154 /UG=Hs.301696 hypothetical protein FLJ11560 /FL=gb:NM_025182.1 NM_025182 family with sequence similarity 214, member B FAM214B 80256 NM_025182 /// XM_005251588 /// XM_005251589 /// XM_005251590 /// XM_005251591 /// XM_005251592 /// XM_005251593 /// XM_005251594 /// XM_005251595 /// XM_005251596 /// XM_005251597 /// XM_005251598 /// XM_006716877 /// XM_006716878 0005634 // nucleus // inferred from direct assay 207766_at NM_004196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004196.2 /DEF=Homo sapiens cyclin-dependent kinase-like 1 (CDC2-related kinase) (CDKL1), mRNA. /FEA=mRNA /GEN=CDKL1 /PROD=cyclin-dependent kinase-like 1 /DB_XREF=gi:11125775 /UG=Hs.302497 cyclin-dependent kinase-like 1 (CDC2-related kinase) /FL=gb:NM_004196.2 NM_004196 cyclin-dependent kinase-like 1 (CDC2-related kinase) CDKL1 8814 NM_001282236 /// NM_004196 /// XM_005268156 /// XM_005268157 /// XM_005268158 /// XM_005268159 /// XM_005268160 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 207767_s_at NM_001965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001965.1 /DEF=Homo sapiens early growth response 4 (EGR4), mRNA. /FEA=mRNA /GEN=EGR4 /PROD=early growth response 4 /DB_XREF=gi:4503494 /UG=Hs.3052 early growth response 4 /FL=gb:NM_001965.1 NM_001965 early growth response 4 EGR4 1961 NM_001965 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0043066 // negative regulation of apoptotic process // not recorded /// 0071320 // cellular response to cAMP // not recorded /// 0071371 // cellular response to gonadotropin stimulus // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207768_at NM_001965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001965.1 /DEF=Homo sapiens early growth response 4 (EGR4), mRNA. /FEA=mRNA /GEN=EGR4 /PROD=early growth response 4 /DB_XREF=gi:4503494 /UG=Hs.3052 early growth response 4 /FL=gb:NM_001965.1 NM_001965 early growth response 4 EGR4 1961 NM_001965 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0043066 // negative regulation of apoptotic process // not recorded /// 0071320 // cellular response to cAMP // not recorded /// 0071371 // cellular response to gonadotropin stimulus // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207769_s_at NM_005710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005710.1 /DEF=Homo sapiens polyglutamine binding protein 1 (PQBP1), mRNA. /FEA=mRNA /GEN=PQBP1 /PROD=polyglutamine binding protein 1 /DB_XREF=gi:5031956 /UG=Hs.30570 polyglutamine binding protein 1 /FL=gb:AJ005893.1 gb:NM_005710.1 NM_005710 polyglutamine binding protein 1 PQBP1 10084 NM_001032381 /// NM_001032382 /// NM_001032383 /// NM_001032384 /// NM_001032385 /// NM_001167989 /// NM_001167990 /// NM_001167992 /// NM_005710 /// NM_144494 /// NM_144495 /// XM_005272571 /// XM_005272572 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034063 // stress granule assembly // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 207770_x_at NM_022644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022644.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 2, mRNA. /FEA=mRNA /GEN=CSH2 /PROD=chorionic somatomammotropin hormone 2, isoform 2precursor /DB_XREF=gi:12408691 /UG=Hs.306155 chorionic somatomammotropin hormone 2 /FL=gb:NM_022644.1 NM_022644 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 CSH1 /// CSH2 1442 /// 1443 NM_001317 /// NM_020991 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 0007165 // signal transduction // non-traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207771_at NM_003041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003041.1 /DEF=Homo sapiens solute carrier family 5 (sodiumglucose cotransporter), member 2 (SLC5A2), mRNA. /FEA=mRNA /GEN=SLC5A2 /PROD=solute carrier family 5 (sodiumglucosecotransporter), member 2 /DB_XREF=gi:4507032 /UG=Hs.306176 solute carrier family 5 (sodiumglucose cotransporter), member 2 /FL=gb:M95549.1 gb:NM_003041.1 NM_003041 solute carrier family 5 (sodium/glucose cotransporter), member 2 SLC5A2 6524 NM_003041 /// XM_006721072 /// XM_006721073 /// XR_243297 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005362 // low-affinity glucose:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 207772_s_at NM_019854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019854.1 /DEF=Homo sapiens HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 3 (HRMT1L3), mRNA. /FEA=mRNA /GEN=HRMT1L3 /PROD=HMT1 (hnRNP methyltransferase, S.cerevisiae)-like 3 /DB_XREF=gi:9789978 /UG=Hs.306210 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 3 /FL=gb:AF263539.1 gb:NM_019854.1 NM_019854 protein arginine methyltransferase 8 PRMT8 56341 NM_001256536 /// NM_001256537 /// NM_019854 /// NR_046301 /// XM_006718986 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0018216 // peptidyl-arginine methylation // inferred from direct assay /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // inferred from direct assay /// 0043393 // regulation of protein binding // traceable author statement /// 0043985 // histone H4-R3 methylation // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // inferred from direct assay /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0035241 // protein-arginine omega-N monomethyltransferase activity // inferred from direct assay /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044020 // histone methyltransferase activity (H4-R3 specific) // not recorded /// 0046982 // protein heterodimerization activity // inferred from direct assay 207773_x_at NM_022820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022820.2 /DEF=Homo sapiens cytochrome P450 polypeptide 43 (CYP3A43), mRNA. /FEA=mRNA /GEN=CYP3A43 /PROD=cytochrome P450 polypeptide 43 /DB_XREF=gi:13386503 /UG=Hs.306220 cytochrome P450 polypeptide 43 /FL=gb:AF280108.1 gb:AF280109.1 gb:AF319634.1 gb:NM_022820.2 NM_022820 cytochrome P450, family 3, subfamily A, polypeptide 43 CYP3A43 64816 NM_001278921 /// NM_022820 /// NM_057095 /// NM_057096 /// NR_103868 /// NR_103869 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207774_at NM_025020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025020.1 /DEF=Homo sapiens hypothetical protein FLJ13954 (FLJ13954), mRNA. /FEA=mRNA /GEN=FLJ13954 /PROD=hypothetical protein FLJ13954 /DB_XREF=gi:13489080 /UG=Hs.306235 hypothetical protein FLJ13954 /FL=gb:NM_025020.1 NM_025020 autophagy related 10 ATG10 83734 NM_001131028 /// NM_031482 /// XM_005248610 /// XM_005248611 /// XM_005248612 0006497 // protein lipidation // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0031401 // positive regulation of protein modification process // inferred from sequence or structural similarity /// 0032446 // protein modification by small protein conjugation // inferred from direct assay /// 0034263 // autophagy in response to ER overload // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation /// 0019777 // Atg12 ligase activity // inferred from sequence or structural similarity 207775_at NM_024304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024304.1 /DEF=Homo sapiens hypothetical protein MGC4859 similar to HSPA8 (MGC4859), mRNA. /FEA=mRNA /GEN=MGC4859 /PROD=hypothetical protein MGC4859 similar to HSPA8 /DB_XREF=gi:13236533 /UG=Hs.306991 hypothetical protein MGC4859 similar to HSPA8 /FL=gb:BC002644.1 gb:NM_024304.1 NM_024304 uncharacterized LOC79150 MGC4859 79150 207776_s_at NM_000724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000724.1 /DEF=Homo sapiens calcium channel, voltage-dependent, beta 2 subunit (CACNB2), mRNA. /FEA=mRNA /GEN=CACNB2 /PROD=calcium channel, voltage-dependent, beta 2subunit /DB_XREF=gi:4502532 /UG=Hs.30941 calcium channel, voltage-dependent, beta 2 subunit /FL=gb:U95019.1 gb:NM_000724.1 gb:AF137377.1 NM_000724 calcium channel, voltage-dependent, beta 2 subunit CACNB2 783 NM_000724 /// NM_001167945 /// NM_201570 /// NM_201571 /// NM_201572 /// NM_201590 /// NM_201593 /// NM_201596 /// NM_201597 /// XM_005252588 /// XM_005252591 /// XM_006717502 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay 207777_s_at NM_007237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007237.1 /DEF=Homo sapiens nuclear body protein Sp140 (SP140), mRNA. /FEA=mRNA /GEN=SP140 /PROD=nuclear body protein Sp140 /DB_XREF=gi:6005879 /UG=Hs.309943 nuclear body protein Sp140 /FL=gb:U63420.1 gb:NM_007237.1 NM_007237 uncharacterized LOC101928789 /// SP140 nuclear body protein LOC101928789 /// SP140 11262 /// 101928789 NM_001005176 /// NM_001278451 /// NM_001278452 /// NM_001278453 /// NM_007237 /// XM_005246252 /// XM_005246253 /// XM_005246254 /// XM_005246255 /// XM_005246256 /// XM_005246257 /// XM_005246258 /// XM_006712223 /// XM_006712224 /// XM_006712225 /// XM_006712226 /// XR_241278 /// XR_241423 /// XR_249318 /// XR_251293 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006952 // defense response // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207778_at NM_006508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006508.1 /DEF=Homo sapiens rat regenerating islet-derived-like, human homolog (pancreatic stone protein-like, pancreatic thread protein-like) (REGL), mRNA. /FEA=mRNA /GEN=REGL /PROD=rat regenerating islet-derived-like, humanhomolog (pancreatic stone protein-like, pancreatic threadprotein-like) /DB_XREF=gi:10835249 /UG=Hs.3191 rat regenerating islet-derived-like, human homolog (pancreatic stone protein-like, pancreatic thread protein-like) /FL=gb:NM_006508.1 NM_006508 regenerating islet-derived 1 pseudogene REG1P 5969 NR_002714 207779_at NM_016344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016344.1 /DEF=Homo sapiens PRO1900 protein (PRO1900), mRNA. /FEA=mRNA /GEN=PRO1900 /PROD=PRO1900 protein /DB_XREF=gi:7706652 /UG=Hs.322437 PRO1900 protein /FL=gb:AF118081.1 gb:NM_016344.1 NM_016344 207780_at NM_001340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001340.1 /DEF=Homo sapiens cylicin, basic protein of sperm head cytoskeleton 2 (CYLC2), mRNA. /FEA=mRNA /GEN=CYLC2 /PROD=cylicin 2 /DB_XREF=gi:4557508 /UG=Hs.3232 cylicin, basic protein of sperm head cytoskeleton 2 /FL=gb:NM_001340.1 NM_001340 cylicin, basic protein of sperm head cytoskeleton 2 CYLC2 1539 NM_001340 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0033150 // cytoskeletal calyx // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation 207781_s_at NM_021998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021998.1 /DEF=Homo sapiens zinc finger protein 6 (CMPX1) (ZNF6), mRNA. /FEA=mRNA /GEN=ZNF6 /PROD=zinc finger protein 6 (CMPX1) /DB_XREF=gi:11527399 /UG=Hs.323950 zinc finger protein 6 (CMPX1) /FL=gb:NM_021998.1 NM_021998 zinc finger protein 711 ZNF711 7552 NM_021998 /// XM_005262186 /// XM_005262187 /// XM_005262188 /// XM_005262189 /// XM_006724687 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207782_s_at NM_007319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007319.1 /DEF=Homo sapiens presenilin 1 (Alzheimer disease 3) (PSEN1), transcript variant I-374., mRNA. /FEA=mRNA /GEN=PSEN1 /PROD=presenilin 1 isoform I-374 /DB_XREF=gi:7549814 /UG=Hs.3260 presenilin 1 (Alzheimer disease 3) /FL=gb:U40380.1 gb:NM_007319.1 NM_007319 presenilin 1 PSEN1 5663 NM_000021 /// NM_007318 /// NM_007319 /// XM_005267864 /// XM_005267866 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015871 // choline transport // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021870 // Cajal-Retzius cell differentiation // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from genetic interaction /// 0034205 // beta-amyloid formation // inferred from electronic annotation /// 0035282 // segmentation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from electronic annotation /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // not recorded /// 0051604 // protein maturation // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // /// 0060075 // regulation of resting membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0031965 // nuclear membrane // inferred from direct assay /// 0035253 // ciliary rootlet // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // not recorded /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // not recorded /// 0070765 // gamma-secretase complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0045296 // cadherin binding // not recorded 207783_x_at NM_017627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017627.1 /DEF=Homo sapiens hypothetical protein FLJ20030 (FLJ20030), mRNA. /FEA=mRNA /GEN=FLJ20030 /PROD=hypothetical protein FLJ20030 /DB_XREF=gi:8923031 /UG=Hs.326456 hypothetical protein FLJ20030 /FL=gb:NM_017627.1 NM_017627 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase HUWE1 10075 NM_031407 /// XM_005261965 /// XM_005261966 /// XM_005261967 /// XM_005261968 /// XM_005261969 /// XM_005261971 /// XM_005261972 /// XM_006724574 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207784_at NM_009589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_009589.1 /DEF=Homo sapiens arylsulfatase D (ARSD), transcript variant 2, mRNA. /FEA=mRNA /GEN=ARSD /PROD=arylsulfatase D precursor, isoform b /DB_XREF=gi:6806884 /UG=Hs.326525 arylsulfatase D /FL=gb:AF160499.1 gb:NM_009589.1 NM_009589 arylsulfatase D ARSD 414 NM_001669 /// NM_009589 /// XM_005274514 /// XM_005274515 /// XM_005274516 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207785_s_at NM_015874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015874.1 /DEF=Homo sapiens H-2K binding factor-2 (LOC51580), mRNA. /FEA=mRNA /GEN=LOC51580 /PROD=H-2K binding factor-2 /DB_XREF=gi:7706215 /UG=Hs.327138 H-2K binding factor-2 /FL=gb:D14041.1 gb:NM_015874.1 NM_015874 recombination signal binding protein for immunoglobulin kappa J region RBPJ 3516 NM_005349 /// NM_015874 /// NM_203283 /// NM_203284 /// XM_005248161 /// XM_006713962 /// XM_006713963 /// XM_006713964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003157 // endocardium development // inferred from electronic annotation /// 0003160 // endocardium morphogenesis // inferred from sequence or structural similarity /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009912 // auditory receptor cell fate commitment // inferred from electronic annotation /// 0009957 // epidermal cell fate specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048820 // hair follicle maturation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060486 // Clara cell differentiation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060844 // arterial endothelial cell fate commitment // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072554 // blood vessel lumenization // inferred from sequence or structural similarity /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0097101 // blood vessel endothelial cell fate specification // inferred from sequence or structural similarity /// 1901186 // positive regulation of ERBB signaling pathway // inferred from sequence or structural similarity /// 1901189 // positive regulation of ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000150 // recombinase activity // non-traceable author statement /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 207786_at NM_024514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024514.1 /DEF=Homo sapiens hypothetical protein MGC4663 (MGC4663), mRNA. /FEA=mRNA /GEN=MGC4663 /PROD=hypothetical protein MGC4663 /DB_XREF=gi:13375649 /UG=Hs.326555 hypothetical protein MGC4663 /FL=gb:BC003642.1 gb:NM_024514.1 NM_024514 cytochrome P450, family 2, subfamily R, polypeptide 1 CYP2R1 120227 NM_024514 /// XM_005252788 /// XM_005252789 /// XM_005252790 /// XM_005252791 /// XM_006718142 /// XM_006718143 /// XR_242777 0006766 // vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010164 // response to cesium ion // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0036378 // calcitriol biosynthetic process from calciol // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207787_at NM_002279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002279.2 /DEF=Homo sapiens keratin, hair, acidic,3B (KRTHA3B), mRNA. /FEA=mRNA /GEN=KRTHA3B /PROD=type I hair keratin 3B /DB_XREF=gi:11641405 /UG=Hs.32950 keratin, hair, acidic,3B /FL=gb:NM_002279.2 NM_002279 keratin 33B KRT33B 3884 NM_002279 0007568 // aging // inferred from direct assay /// 0042633 // hair cycle // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 207788_s_at NM_005775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005775.1 /DEF=Homo sapiens vinexin beta (SH3-containing adaptor molecule-1) (SCAM-1), mRNA. /FEA=mRNA /GEN=SCAM-1 /PROD=vinexin beta (SH3-containing adaptormolecule-1) /DB_XREF=gi:5032072 /UG=Hs.33787 vinexin beta (SH3-containing adaptor molecule-1) /FL=gb:AF064807.1 gb:NM_005775.1 NM_005775 sorbin and SH3 domain containing 3 SORBS3 10174 NM_001018003 /// NM_005775 /// XM_005273370 /// XM_005273371 /// XM_006716266 /// XM_006716267 /// XM_006716268 /// XM_006716269 /// XM_006716270 /// XM_006716271 /// XR_428299 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051495 // positive regulation of cytoskeleton organization // non-traceable author statement /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction 207789_s_at NM_001936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001936.1 /DEF=Homo sapiens dipeptidylpeptidase VI (DPP6), mRNA. /FEA=mRNA /GEN=DPP6 /PROD=dipeptidylpeptidase VI /DB_XREF=gi:4503368 /UG=Hs.34074 dipeptidylpeptidase VI /FL=gb:M96860.1 gb:NM_001936.1 NM_001936 dipeptidyl-peptidase 6 DPP6 1804 NM_001039350 /// NM_001290252 /// NM_001290253 /// NM_001936 /// NM_130797 /// XM_006715871 /// XM_006715872 0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043266 // regulation of potassium ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // traceable author statement 207790_at NM_025168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025168.1 /DEF=Homo sapiens hypothetical protein FLJ10775 (FLJ10775), mRNA. /FEA=mRNA /GEN=FLJ10775 /PROD=hypothetical protein FLJ11834 /DB_XREF=gi:13378148 /UG=Hs.35091 hypothetical protein FLJ10775 /FL=gb:NM_025168.1 NM_025168 leucine rich repeat containing 1 LRRC1 55227 NM_018214 /// NM_025168 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 207791_s_at NM_004161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004161.1 /DEF=Homo sapiens RAB1, member RAS oncogene family (RAB1), mRNA. /FEA=mRNA /GEN=RAB1 /PROD=RAB1, member RAS oncogene family /DB_XREF=gi:4758987 /UG=Hs.3642 RAB1, member RAS oncogene family /FL=gb:NM_004161.1 gb:M28209.1 NM_004161 RAB1A, member RAS oncogene family RAB1A 5861 NM_004161 /// NM_015543 /// XM_005264468 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030252 // growth hormone secretion // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0072606 // interleukin-8 secretion // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 207792_at NM_000911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000911.1 /DEF=Homo sapiens opioid receptor, delta 1 (OPRD1), mRNA. /FEA=mRNA /GEN=OPRD1 /PROD=opioid receptor, delta 1 /DB_XREF=gi:4505508 /UG=Hs.372 opioid receptor, delta 1 /FL=gb:NM_000911.1 gb:U07882.1 gb:U10504.1 NM_000911 opioid receptor, delta 1 OPRD1 4985 NM_000911 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0038003 // opioid receptor signaling pathway // inferred from mutant phenotype /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0038046 // enkephalin receptor activity // inferred from mutant phenotype 207793_s_at NM_004437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004437.1 /DEF=Homo sapiens erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (EPB41), mRNA. /FEA=mRNA /GEN=EPB41 /PROD=erythrocyte membrane protein band 4.1(elliptocytosis 1, RH-linked) /DB_XREF=gi:4758273 /UG=Hs.37427 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) /FL=gb:M14993.1 gb:NM_004437.1 NM_004437 erythrocyte membrane protein band 4.1 EPB41 2035 NM_001166005 /// NM_001166006 /// NM_001166007 /// NM_004437 /// NM_203342 /// NM_203343 /// XM_005245753 /// XM_005245757 /// XM_005245760 /// XM_005245761 /// XM_005245763 /// XM_005245764 /// XM_005245765 /// XM_005245767 /// XM_005245768 /// XM_005245769 /// XM_005245770 /// XM_005245772 /// XM_005245773 /// XM_005245774 /// XM_006710434 /// XM_006710435 /// XM_006710436 /// XM_006710437 /// XM_006710438 /// XM_006710439 /// XM_006710440 0008015 // blood circulation // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0014731 // spectrin-associated cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // traceable author statement 207794_at NM_000648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000648.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 2 (CCR2), mRNA. /FEA=mRNA /GEN=CCR2 /PROD=chemokine (C-C motif) receptor 2 /DB_XREF=gi:4757937 /UG=Hs.395 chemokine (C-C motif) receptor 2 /FL=gb:U03905.1 gb:NM_000648.1 gb:D29984.1 NM_000648 chemokine (C-C motif) receptor 2 CCR2 729230 NM_001123041 /// NM_001123396 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002829 // negative regulation of type 2 immune response // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0010574 // regulation of vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0010820 // positive regulation of T cell chemotaxis // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019725 // cellular homeostasis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032743 // positive regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0035705 // T-helper 17 cell chemotaxis // inferred from sequence or structural similarity /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from sequence or structural similarity /// 0043310 // negative regulation of eosinophil degranulation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from sequence or structural similarity /// 0090265 // positive regulation of immune complex clearance by monocytes and macrophages // inferred from sequence or structural similarity /// 2000439 // positive regulation of monocyte extravasation // inferred from sequence or structural similarity /// 2000451 // positive regulation of CD8-positive, alpha-beta T cell extravasation // inferred from sequence or structural similarity /// 2000464 // positive regulation of astrocyte chemotaxis // inferred from direct assay /// 2000473 // positive regulation of hematopoietic stem cell migration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation /// 0031727 // CCR2 chemokine receptor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 207795_s_at AB009597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009597.1 /DEF=Homo sapiens mRNA for CD94, complete cds. /FEA=mRNA /GEN=CD94 alt /PROD=CD94 /DB_XREF=gi:2804283 /UG=Hs.41682 killer cell lectin-like receptor subfamily D, member 1 /FL=gb:AB009597.1 gb:NM_007334.1 AB009597 killer cell lectin-like receptor subfamily D, member 1 KLRD1 3824 NM_001114396 /// NM_002262 /// NM_007334 /// XM_005253363 /// XM_006719065 /// XM_006719066 /// XM_006719067 /// XM_006719068 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 207796_x_at NM_007334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007334.1 /DEF=Homo sapiens killer cell lectin-like receptor subfamily D, member 1 (KLRD1), transcript variant 2, mRNA. /FEA=mRNA /GEN=KLRD1 /PROD=killer cell lectin-like receptor subfamily D,member 1 isoform 2 /DB_XREF=gi:7669498 /UG=Hs.41682 killer cell lectin-like receptor subfamily D, member 1 /FL=gb:AB009597.1 gb:NM_007334.1 NM_007334 killer cell lectin-like receptor subfamily D, member 1 KLRD1 3824 NM_001114396 /// NM_002262 /// NM_007334 /// XM_005253363 /// XM_006719065 /// XM_006719066 /// XM_006719067 /// XM_006719068 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 207797_s_at NM_018409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018409.1 /DEF=Homo sapiens hypothetical protein DKFZp761O0113 (DKFZp761O0113), mRNA. /FEA=mRNA /GEN=DKFZp761O0113 /PROD=hypothetical protein DKFZp761O0113 /DB_XREF=gi:8922176 /UG=Hs.42768 hypothetical protein DKFZp761O0113 /FL=gb:NM_018409.1 NM_018409 LRP2 binding protein LRP2BP 55805 NM_018409 /// XM_005263123 /// XM_005263124 /// XM_005263125 /// XM_006714260 /// XM_006714261 /// XM_006714262 /// XM_006714263 /// XM_006714264 /// XM_006714265 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207798_s_at NM_017492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017492.1 /DEF=Homo sapiens ataxin 2 related protein (A2LP), transcript variant 2, mRNA. /FEA=mRNA /GEN=A2LP /PROD=ataxin 2 related protein, isoform 2 /DB_XREF=gi:9665244 /UG=Hs.43509 ataxin 2 related protein /FL=gb:NM_017492.1 NM_017492 ataxin 2-like ATXN2L 11273 NM_007245 /// NM_017492 /// NM_145714 /// NM_148414 /// NM_148415 /// NM_148416 /// XM_005255061 /// XM_005255062 /// XM_005255063 /// XM_005255064 /// XM_005255065 /// XM_005255066 /// XM_005255067 /// XM_005255068 /// XM_005255069 /// XM_005255070 /// XM_005255071 /// XM_005255072 /// XM_005255074 /// XM_005255075 /// XM_005255076 /// XM_005255077 /// XM_006721007 /// XM_006721008 /// XM_006721009 /// XM_006721010 /// XM_006721011 /// XM_006721012 /// XM_006721013 /// XR_243256 0010603 // regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0034063 // stress granule assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207799_x_at NM_015437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015437.1 /DEF=Homo sapiens DKFZP586N0819 protein (DKFZP586N0819), mRNA. /FEA=mRNA /GEN=DKFZP586N0819 /PROD=DKFZP586N0819 protein /DB_XREF=gi:7661693 /UG=Hs.47144 DKFZP586N0819 protein /FL=gb:NM_015437.1 NM_015437 armadillo repeat containing, X-linked 4 ARMCX4 100131755 NM_001256155 /// NM_152583 /// NR_028407 /// NR_045861 /// NR_045862 /// NR_045863 /// NR_045864 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207800_at NM_004857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004857.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 5 (AKAP5), mRNA. /FEA=mRNA /GEN=AKAP5 /PROD=A kinase (PRKA) anchor protein 5 /DB_XREF=gi:4757739 /UG=Hs.48714 A kinase (PRKA) anchor protein 5 /FL=gb:M90359.1 gb:NM_004857.1 NM_004857 A kinase (PRKA) anchor protein 5 AKAP5 9495 NM_004857 0006112 // energy reserve metabolic process // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0010739 // positive regulation of protein kinase A signaling // inferred from mutant phenotype /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008179 // adenylate cyclase binding // inferred from physical interaction /// 0051018 // protein kinase A binding // traceable author statement 207801_s_at NM_014868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014868.1 /DEF=Homo sapiens ring finger protein 10 (RNF10), mRNA. /FEA=mRNA /GEN=RNF10 /PROD=ring finger protein 10 /DB_XREF=gi:7662652 /UG=Hs.5094 ring finger protein 10 /FL=gb:D87451.1 gb:NM_014868.1 NM_014868 ring finger protein 10 RNF10 9921 NM_014868 /// XM_005254013 /// XM_005254014 /// XM_006719717 /// XR_243026 /// XR_243027 /// XR_429123 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 207802_at NM_006061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006061.1 /DEF=Homo sapiens specific granule protein (28 kDa); cysteine-rich secretory protein-3 (SGP28), mRNA. /FEA=mRNA /GEN=SGP28 /PROD=specific granule protein (28 kDa); cysteine-richsecretory protein-3 /DB_XREF=gi:5174674 /UG=Hs.54431 specific granule protein (28 kDa); cysteine-rich secretory protein-3 /FL=gb:NM_006061.1 NM_006061 cysteine-rich secretory protein 3 CRISP3 10321 NM_001190986 /// NM_006061 0006952 // defense response // non-traceable author statement /// 0045087 // innate immune response // non-traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 207803_s_at NM_005212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005212.1 /DEF=Homo sapiens casein, kappa (CSN10), mRNA. /FEA=mRNA /GEN=CSN10 /PROD=casein, kappa /DB_XREF=gi:4885160 /UG=Hs.54415 casein, kappa /FL=gb:NM_005212.1 NM_005212 casein kappa CSN3 1448 NM_005212 0007595 // lactation // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay 207804_s_at NM_004108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004108.1 /DEF=Homo sapiens ficolin (collagenfibrinogen domain-containing lectin) 2 (hucolin) (FCN2), transcript variant SV0, mRNA. /FEA=mRNA /GEN=FCN2 /PROD=ficolin 2 isoform a precursor /DB_XREF=gi:4758347 /UG=Hs.54517 ficolin (collagenfibrinogen domain-containing lectin) 2 (hucolin) /FL=gb:D49353.1 gb:NM_004108.1 NM_004108 ficolin (collagen/fibrinogen domain containing lectin) 2 FCN2 2220 NM_004108 /// NM_015837 /// NM_015838 /// NM_015839 /// XM_006717015 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0008228 // opsonization // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 207805_s_at NM_002813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002813.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 (PSMD9), mRNA. /FEA=mRNA /GEN=PSMD9 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 9 /DB_XREF=gi:4506234 /UG=Hs.5648 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 /FL=gb:AB003177.1 gb:NM_002813.1 NM_002813 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 PSMD9 5715 NM_001261400 /// NM_002813 /// NR_048555 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from sequence or structural similarity /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // non-traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from sequence or structural similarity 207808_s_at NM_000313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000313.1 /DEF=Homo sapiens protein S (alpha) (PROS1), mRNA. /FEA=mRNA /GEN=PROS1 /PROD=protein S (alpha) /DB_XREF=gi:4506116 /UG=Hs.64016 protein S (alpha) /FL=gb:M15036.1 gb:NM_000313.1 NM_000313 protein S (alpha) PROS1 5627 NM_000313 /// XM_005247626 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207809_s_at NM_001183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001183.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 (ATP6S1), mRNA. /FEA=mRNA /GEN=ATP6S1 /PROD=ATPase, H+ transporting, lysosomal subunit 1 /DB_XREF=gi:4557340 /UG=Hs.6551 ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 /FL=gb:NM_001183.1 NM_001183 ATPase, H+ transporting, lysosomal accessory protein 1 ATP6AP1 537 NM_001183 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0045851 // pH reduction // inferred from sequence or structural similarity /// 0045921 // positive regulation of exocytosis // inferred from sequence or structural similarity /// 0051656 // establishment of organelle localization // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 2001206 // positive regulation of osteoclast development // inferred from sequence or structural similarity 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 207810_at NM_001994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001994.1 /DEF=Homo sapiens coagulation factor XIII, B polypeptide (F13B), mRNA. /FEA=mRNA /GEN=F13B /PROD=coagulation factor XIII B subunit precursor /DB_XREF=gi:9961356 /UG=Hs.68601 coagulation factor XIII, B polypeptide /FL=gb:NM_001994.1 NM_001994 coagulation factor XIII, B polypeptide F13B 2165 NM_001994 /// XM_005244953 /// XM_005244954 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement 207811_at NM_000223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000223.1 /DEF=Homo sapiens keratin 12 (Meesmann corneal dystrophy) (KRT12), mRNA. /FEA=mRNA /GEN=KRT12 /PROD=keratin 12 /DB_XREF=gi:4557698 /UG=Hs.66739 keratin 12 (Meesmann corneal dystrophy) /FL=gb:D78367.1 gb:NM_000223.1 NM_000223 keratin 12 KRT12 3859 NM_000223 0007601 // visual perception // traceable author statement /// 0060429 // epithelium development // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 207812_s_at NM_015530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015530.1 /DEF=Homo sapiens DKFZP434D156 protein (DKFZP434D156), mRNA. /FEA=mRNA /GEN=DKFZP434D156 /PROD=DKFZP434D156 protein /DB_XREF=gi:7661569 /UG=Hs.6880 DKFZP434D156 protein /FL=gb:NM_015530.1 NM_015530 golgi reassembly stacking protein 2, 55kDa GORASP2 26003 NM_001201428 /// NM_015530 /// XM_006712408 0000278 // mitotic cell cycle // traceable author statement /// 0006996 // organelle organization // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 207813_s_at NM_004110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004110.2 /DEF=Homo sapiens ferredoxin reductase (FDXR), transcript variant 2, nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FDXR /PROD=ferredoxin reductase isoform 2 precursor /DB_XREF=gi:13435351 /UG=Hs.69745 ferredoxin reductase /FL=gb:NM_004110.2 gb:J03826.1 NM_004110 ferredoxin reductase FDXR 2232 NM_001258012 /// NM_001258013 /// NM_001258014 /// NM_001258015 /// NM_001258016 /// NM_004110 /// NM_024417 /// NR_047576 /// XM_006721772 /// XM_006721773 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0070995 // NADPH oxidation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0004324 // ferredoxin-NADP+ reductase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015039 // NADPH-adrenodoxin reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from electronic annotation 207814_at NM_001926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001926.2 /DEF=Homo sapiens defensin, alpha 6, Paneth cell-specific (DEFA6), mRNA. /FEA=mRNA /GEN=DEFA6 /PROD=defensin, alpha 6, preproprotein /DB_XREF=gi:12621917 /UG=Hs.711 defensin, alpha 6, Paneth cell-specific /FL=gb:NM_001926.2 gb:M98331.1 NM_001926 defensin, alpha 6, Paneth cell-specific DEFA6 1671 NM_001926 0006952 // defense response // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement 207815_at NM_002620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002620.1 /DEF=Homo sapiens platelet factor 4 variant 1 (PF4V1), mRNA. /FEA=mRNA /GEN=PF4V1 /PROD=platelet factor 4 variant 1 /DB_XREF=gi:4505734 /UG=Hs.72933 platelet factor 4 variant 1 /FL=gb:NM_002620.1 NM_002620 platelet factor 4 variant 1 PF4V1 5197 NM_002620 0006955 // immune response // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 207816_at NM_002289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002289.1 /DEF=Homo sapiens lactalbumin, alpha- (LALBA), mRNA. /FEA=mRNA /GEN=LALBA /PROD=lactalbumin, alpha- /DB_XREF=gi:4504946 /UG=Hs.72938 lactalbumin, alpha- /FL=gb:J00270.1 gb:NM_002289.1 NM_002289 lactalbumin, alpha- LALBA 3906 NM_002289 /// XM_006719395 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0004461 // lactose synthase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207817_at NM_002177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002177.1 /DEF=Homo sapiens interferon, omega 1 (IFNW1), mRNA. /FEA=mRNA /GEN=IFNW1 /PROD=interferon, omega 1 /DB_XREF=gi:4504604 /UG=Hs.73010 interferon, omega 1 /FL=gb:NM_002177.1 NM_002177 interferon, omega 1 IFNW1 3467 NM_002177 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007050 // cell cycle arrest // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 207818_s_at NM_000872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000872.2 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) (HTR7), transcript variant a, mRNA. /FEA=mRNA /GEN=HTR7 /PROD=5-hydroxytryptamine receptor 7, isoform a /DB_XREF=gi:10880132 /UG=Hs.73739 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) /FL=gb:NM_019860.1 gb:NM_000872.2 gb:U68487.1 gb:L21195.1 NM_000872 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled HTR7 3363 NM_000872 /// NM_019859 /// NM_019860 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0042310 // vasoconstriction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 207819_s_at NM_000443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000443.2 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 4 (ABCB4), transcript variant A, mRNA. /FEA=mRNA /GEN=ABCB4 /PROD=ATP-binding cassette, subfamily B, member 4,isoform A /DB_XREF=gi:9961253 /UG=Hs.73812 ATP-binding cassette, sub-family B (MDRTAP), member 4 /FL=gb:M23234.1 gb:NM_000443.2 NM_000443 ATP-binding cassette, sub-family B (MDR/TAP), member 4 ABCB4 5244 NM_000443 /// NM_018849 /// NM_018850 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006855 // drug transmembrane transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded 0000139 // Golgi membrane // /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0016324 // apical plasma membrane // /// 0046581 // intercellular canaliculus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008559 // xenobiotic-transporting ATPase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 207820_at NM_000667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000667.2 /DEF=Homo sapiens alcohol dehydrogenase 1 (class I), alpha polypeptide (ADH1), mRNA. /FEA=mRNA /GEN=ADH1 /PROD=class I alcohol dehydrogenase 1 alpha subunit /DB_XREF=gi:11496886 /UG=Hs.73843 alcohol dehydrogenase 1 (class I), alpha polypeptide /FL=gb:NM_000667.2 gb:M12963.1 gb:M12271.1 NM_000667 alcohol dehydrogenase 1A (class I), alpha polypeptide ADH1A 124 NM_000667 0006066 // alcohol metabolic process // non-traceable author statement /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // traceable author statement /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207821_s_at NM_005607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005607.1 /DEF=Homo sapiens PTK2 protein tyrosine kinase 2 (PTK2), mRNA. /FEA=mRNA /GEN=PTK2 /PROD=PTK2 protein tyrosine kinase 2 /DB_XREF=gi:5032000 /UG=Hs.740 PTK2 protein tyrosine kinase 2 /FL=gb:L05186.1 gb:NM_005607.1 NM_005607 protein tyrosine kinase 2 PTK2 5747 NM_001199649 /// NM_005607 /// NM_153831 /// XM_005251003 /// XM_005251004 /// XM_005251005 /// XM_005251006 /// XM_005251007 /// XM_005251008 /// XM_005251009 /// XM_005251010 /// XM_005251011 /// XM_005251012 /// XM_005251013 /// XM_005251014 /// XM_006716606 /// XM_006716607 /// XM_006716608 /// XM_006716609 /// XM_006716610 0000165 // MAPK cascade // inferred from electronic annotation /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001890 // placenta development // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010594 // regulation of endothelial cell migration // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0038007 // netrin-activated signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048870 // cell motility // traceable author statement /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008432 // JUN kinase binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation 207822_at NM_023107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023107.1 /DEF=Homo sapiens fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) (FGFR1), transcript variant 5, mRNA. /FEA=mRNA /GEN=FGFR1 /PROD=fibroblast growth factor receptor 1, isoform 5precursor /DB_XREF=gi:13186237 /UG=Hs.748 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) /FL=gb:NM_023107.1 gb:NM_023108.1 gb:M34187.1 gb:M34188.1 NM_023107 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 207823_s_at NM_004847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004847.2 /DEF=Homo sapiens allograft inflammatory factor 1 (AIF1), mRNA. /FEA=mRNA /GEN=AIF1 /PROD=interferon gamma responsive transcript /DB_XREF=gi:6680470 /UG=Hs.76364 allograft inflammatory factor 1 /FL=gb:NM_004847.2 NM_004847 allograft inflammatory factor 1 AIF1 199 NM_001623 /// NM_004847 /// NM_032955 /// XM_005248869 /// XM_005248870 /// XM_005248871 /// XM_005272777 /// XM_005272778 /// XM_005272779 /// XM_005274923 /// XM_005274924 /// XM_005274925 /// XM_005275219 /// XM_005275220 /// XM_005275221 /// XM_005275355 /// XM_005275356 /// XM_005275357 /// XM_005275514 /// XM_005275515 /// XM_005275516 0001774 // microglial cell activation // non-traceable author statement /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006954 // inflammatory response // non-traceable author statement /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030041 // actin filament polymerization // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from sequence or structural similarity /// 0071672 // negative regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0097178 // ruffle assembly // inferred from sequence or structural similarity /// 0097178 // ruffle assembly // non-traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 207824_s_at NM_002383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002383.1 /DEF=Homo sapiens MYC-associated zinc finger protein (purine-binding transcription factor) (MAZ), mRNA. /FEA=mRNA /GEN=MAZ /PROD=MYC-associated zinc finger protein(purine-binding transcription factor) /DB_XREF=gi:13399295 /UG=Hs.7647 MYC-associated zinc finger protein (purine-binding transcription factor) /FL=gb:NM_002383.1 gb:D85131.1 NM_002383 MYC-associated zinc finger protein (purine-binding transcription factor) MAZ 4150 NM_001042539 /// NM_001276275 /// NM_001276276 /// NM_002383 /// NR_074080 /// XM_006721047 /// XM_006721048 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 207825_s_at NM_000823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000823.1 /DEF=Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. /FEA=mRNA /GEN=GHRHR /PROD=growth hormone releasing hormone receptor /DB_XREF=gi:4503996 /UG=Hs.767 growth hormone releasing hormone receptor /FL=gb:L01406.1 gb:NM_000823.1 NM_000823 growth hormone releasing hormone receptor GHRHR 2692 NM_000823 /// NM_001009824 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033143 // regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // non-traceable author statement /// 0043627 // response to estrogen // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // non-traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0060124 // positive regulation of growth hormone secretion // non-traceable author statement /// 0060133 // somatotropin secreting cell development // inferred from electronic annotation 0005637 // nuclear inner membrane // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0016520 // growth hormone-releasing hormone receptor activity // inferred from mutant phenotype /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction 207826_s_at NM_002167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002167.1 /DEF=Homo sapiens inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3), mRNA. /FEA=mRNA /GEN=ID3 /PROD=inhibitor of DNA binding 3, dominant negativehelix-loop-helix protein /DB_XREF=gi:10835060 /UG=Hs.76884 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein /FL=gb:NM_002167.1 NM_002167 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein ID3 3399 NM_002167 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 207827_x_at L36675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L36675.1 /DEF=Human (clone 2-4) synuclein (NACP) mRNA, complete cds. /FEA=mRNA /GEN=NACP /PROD=synuclein /DB_XREF=gi:556213 /UG=Hs.76930 synuclein, alpha (non A4 component of amyloid precursor) /FL=gb:L36675.1 gb:D31839.1 gb:NM_007308.1 L36675 synuclein, alpha (non A4 component of amyloid precursor) SNCA 6622 NM_000345 /// NM_001146054 /// NM_001146055 /// NM_007308 0001774 // microglial cell activation // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006638 // neutral lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from direct assay /// 0010517 // regulation of phospholipase activity // inferred from direct assay /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014048 // regulation of glutamate secretion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032769 // negative regulation of monooxygenase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from direct assay /// 0045920 // negative regulation of exocytosis // inferred from mutant phenotype /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050812 // regulation of acyl-CoA biosynthetic process // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051583 // dopamine uptake involved in synaptic transmission // traceable author statement /// 0051585 // negative regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0051612 // negative regulation of serotonin uptake // inferred from direct assay /// 0051622 // negative regulation of norepinephrine uptake // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0070495 // negative regulation of thrombin receptor signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043205 // fibril // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from direct assay /// 0060961 // phospholipase D inhibitor activity // inferred from direct assay 207828_s_at NM_005196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005196.1 /DEF=Homo sapiens centromere protein F (350400kD, mitosin) (CENPF), mRNA. /FEA=mRNA /GEN=CENPF /PROD=centromere protein F (350400kD, mitosin) /DB_XREF=gi:4885132 /UG=Hs.77204 centromere protein F (350400kD, mitosin) /FL=gb:NM_005196.1 gb:U19769.1 NM_005196 centromere protein F, 350/400kDa CENPF 1063 NM_016343 0000085 // mitotic G2 phase // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from direct assay /// 0000087 // mitotic M phase // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007059 // chromosome segregation // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0015031 // protein transport // inferred from direct assay /// 0015031 // protein transport // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051310 // metaphase plate congression // inferred from direct assay /// 0051382 // kinetochore assembly // non-traceable author statement /// 0051726 // regulation of cell cycle // traceable author statement 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000785 // chromatin // non-traceable author statement /// 0000922 // spindle pole // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0045502 // dynein binding // inferred from direct assay 207829_s_at NM_013978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013978.1 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 1 (BNIP1), transcript variant BNIP1-a, mRNA. /FEA=mRNA /GEN=BNIP1 /PROD=BCL2adenovirus E1B 19kD-interacting protein 1,isoform BNIP1-a /DB_XREF=gi:7524347 /UG=Hs.77572 BCL2adenovirus E1B 19kD-interacting protein 1 /FL=gb:AF083956.1 gb:NM_013978.1 NM_013978 BCL2/adenovirus E1B 19kDa interacting protein 1 BNIP1 662 NM_001205 /// NM_013978 /// NM_013979 /// NM_013980 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from physical interaction /// 0007029 // endoplasmic reticulum organization // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016320 // endoplasmic reticulum membrane fusion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred by curator 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 207830_s_at NM_002713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002713.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), mRNA. /FEA=mRNA /GEN=PPP1R8 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 8 /DB_XREF=gi:4506014 /UG=Hs.78961 protein phosphatase 1, regulatory (inhibitor) subunit 8 /FL=gb:NM_002713.1 gb:U14575.1 NM_002713 protein phosphatase 1, regulatory subunit 8 PPP1R8 5511 NM_002713 /// NM_014110 /// NM_138558 /// XM_006710723 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008599 // protein phosphatase type 1 regulator activity // inferred from electronic annotation /// 0008995 // ribonuclease E activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 207831_x_at NM_013407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013407.1 /DEF=Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 3, mRNA. /FEA=mRNA /GEN=DHPS /PROD=deoxyhypusine synthase isoform c /DB_XREF=gi:7108339 /UG=Hs.79064 deoxyhypusine synthase /FL=gb:NM_013407.1 NM_013407 deoxyhypusine synthase DHPS 1725 NM_001206974 /// NM_001930 /// NM_013406 /// NM_013407 /// NR_038192 0006412 // translation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050983 // deoxyhypusine biosynthetic process from spermidine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0034038 // deoxyhypusine synthase activity // traceable author statement 207832_at NM_017451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017451.1 /DEF=Homo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 2, mRNA. /FEA=mRNA /GEN=BAIAP2 /PROD=BAI1-associated protein 2, isoform 2 /DB_XREF=gi:9257198 /UG=Hs.7936 BAI1-associated protein 2 /FL=gb:AB017119.1 gb:NM_017451.1 NM_017451 BAI1-associated protein 2 BAIAP2 10458 NM_001144888 /// NM_006340 /// NM_017450 /// NM_017451 /// XM_005256943 /// XM_005256944 /// XM_005256945 /// XM_005256948 /// XM_006721635 /// XM_006721636 /// XM_006721637 /// XM_006721638 /// XR_429867 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 207833_s_at NM_000411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000411.1 /DEF=Homo sapiens holocarboxylase synthetase (biotin-proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing) ligase) (HLCS), mRNA. /FEA=mRNA /GEN=HLCS /PROD=holocarboxylase synthetase(biotin-proprionyl-Coenzyme A-carboxylase(ATP-hydrolysing) ligase) /DB_XREF=gi:4504418 /UG=Hs.79375 holocarboxylase synthetase (biotin-proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing) ligase) /FL=gb:NM_000411.1 gb:D23672.1 NM_000411 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) HLCS 3141 NM_000411 /// NM_001242784 /// NM_001242785 /// XM_005260953 /// XM_005260954 /// XM_005260955 /// XM_005260956 /// XM_006723993 /// XM_006723994 /// XM_006723995 /// XM_006723996 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009305 // protein biotinylation // inferred from direct assay /// 0016570 // histone modification // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0070781 // response to biotin // inferred from direct assay /// 0071110 // histone biotinylation // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005652 // nuclear lamina // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004077 // biotin-[acetyl-CoA-carboxylase] ligase activity // inferred from electronic annotation /// 0004078 // biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity // inferred from electronic annotation /// 0004079 // biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity // inferred from electronic annotation /// 0004080 // biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0018271 // biotin-protein ligase activity // inferred from direct assay /// 0018271 // biotin-protein ligase activity // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 207834_at NM_006485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006485.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant B, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform B precursor /DB_XREF=gi:5922006 /UG=Hs.79732 fibulin 1 /FL=gb:NM_006485.1 NM_006485 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 207835_at NM_006487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006487.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant A, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform A precursor /DB_XREF=gi:5922010 /UG=Hs.79732 fibulin 1 /FL=gb:NM_006487.1 NM_006487 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 207836_s_at NM_006867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006867.1 /DEF=Homo sapiens RNA-binding protein gene with multiple splicing (RBPMS), mRNA. /FEA=mRNA /GEN=RBPMS /PROD=RNA-binding protein gene with multiple splicing /DB_XREF=gi:5803140 /UG=Hs.80248 RNA-binding protein gene with multiple splicing /FL=gb:D84110.1 gb:NM_006867.1 NM_006867 RNA binding protein with multiple splicing RBPMS 11030 NM_001008710 /// NM_001008711 /// NM_001008712 /// NM_006867 /// XM_005273386 /// XM_005273390 /// XM_006716277 /// XM_006716278 /// XM_006716279 /// XR_428303 /// XR_428304 /// XR_428305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 207837_at NM_006867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006867.1 /DEF=Homo sapiens RNA-binding protein gene with multiple splicing (RBPMS), mRNA. /FEA=mRNA /GEN=RBPMS /PROD=RNA-binding protein gene with multiple splicing /DB_XREF=gi:5803140 /UG=Hs.80248 RNA-binding protein gene with multiple splicing /FL=gb:D84110.1 gb:NM_006867.1 NM_006867 RNA binding protein with multiple splicing RBPMS 11030 NM_001008710 /// NM_001008711 /// NM_001008712 /// NM_006867 /// XM_005273386 /// XM_005273390 /// XM_006716277 /// XM_006716278 /// XM_006716279 /// XR_428303 /// XR_428304 /// XR_428305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 207838_x_at NM_020524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020524.1 /DEF=Homo sapiens hematopoietic PBX-interacting protein (HPIP), mRNA. /FEA=mRNA /GEN=HPIP /PROD=hematopoietic PBX-interacting protein /DB_XREF=gi:10092622 /UG=Hs.8068 hematopoietic PBX-interacting protein /FL=gb:NM_020524.1 gb:AF221521.1 NM_020524 pre-B-cell leukemia homeobox interacting protein 1 PBXIP1 57326 NM_020524 0007275 // multicellular organismal development // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0003714 // transcription corepressor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207839_s_at NM_016446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016446.1 /DEF=Homo sapiens NAG-5 protein (LOC51754), mRNA. /FEA=mRNA /GEN=LOC51754 /PROD=NAG-5 protein /DB_XREF=gi:7706546 /UG=Hs.8087 NAG-5 protein /FL=gb:AF149297.1 gb:NM_016446.1 NM_016446 transmembrane protein 8B TMEM8B 51754 NM_001042589 /// NM_001042590 /// NM_016446 /// XM_005251483 /// XM_005251484 /// XM_006716780 /// XM_006716781 /// XM_006716782 /// XM_006716783 0006952 // defense response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007346 // regulation of mitotic cell cycle // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207840_at NM_007053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007053.1 /DEF=Homo sapiens natural killer cell receptor, immunoglobulin superfamily member (BY55), mRNA. /FEA=mRNA /GEN=BY55 /PROD=natural killer cell receptor, immunoglobulinsuperfamily member /DB_XREF=gi:5901909 /UG=Hs.81743 natural killer cell receptor, immunoglobulin superfamily member /FL=gb:AF060981.1 gb:NM_007053.1 NM_007053 CD160 molecule CD160 11126 NM_007053 /// NR_103845 /// XM_005272929 /// XM_005272930 0006968 // cellular defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from direct assay /// 0032393 // MHC class I receptor activity // inferred from direct assay 207841_at NM_019003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019003.1 /DEF=Homo sapiens spindlin-like (LOC54466), mRNA. /FEA=mRNA /GEN=LOC54466 /PROD=spindlin-like /DB_XREF=gi:9506850 /UG=Hs.82577 spindlin-like /FL=gb:NM_019003.1 NM_019003 spindlin family, member 2A SPIN2A 54466 NM_019003 /// XM_005262016 /// XM_005262017 /// XM_005262018 /// XM_005262019 /// XM_006724588 0007049 // cell cycle // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation 207842_s_at NM_007359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007359.1 /DEF=Homo sapiens MLN51 protein (MLN51), mRNA. /FEA=mRNA /GEN=MLN51 /PROD=MLN51 protein /DB_XREF=gi:6678887 /UG=Hs.83422 MLN51 protein /FL=gb:NM_007359.1 NM_007359 cancer susceptibility candidate 3 /// microRNA 6866 CASC3 /// MIR6866 22794 /// 102466986 NM_007359 /// NR_106926 /// XM_005257163 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0008298 // intracellular mRNA localization // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 207843_x_at NM_001914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001914.1 /DEF=Homo sapiens cytochrome b-5 (CYB5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CYB5 /PROD=cytochrome b-5 /DB_XREF=gi:4503182 /UG=Hs.83834 cytochrome b-5 /FL=gb:M60174.1 gb:NM_001914.1 NM_001914 cytochrome b5 type A (microsomal) CYB5A 1528 NM_001190807 /// NM_001914 /// NM_148923 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207844_at NM_002188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002188.1 /DEF=Homo sapiens interleukin 13 (IL13), mRNA. /FEA=mRNA /GEN=IL13 /PROD=interleukin 13 /DB_XREF=gi:4504644 /UG=Hs.845 interleukin 13 /FL=gb:L06801.1 gb:AF043334.1 gb:NM_002188.1 NM_002188 interleukin 13 IL13 3596 NM_002188 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010155 // regulation of proton transport // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032723 // positive regulation of connective tissue growth factor production // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042526 // positive regulation of tyrosine phosphorylation of Stat6 protein // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from electronic annotation /// 0043270 // positive regulation of ion transport // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071635 // negative regulation of transforming growth factor beta production // inferred from electronic annotation /// 1901247 // negative regulation of lung ciliated cell differentiation // non-traceable author statement /// 1901251 // positive regulation of lung goblet cell differentiation // non-traceable author statement /// 2000231 // positive regulation of pancreatic stellate cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005144 // interleukin-13 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207845_s_at NM_014885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014885.1 /DEF=Homo sapiens anaphase-promoting complex 10 (APC10), mRNA. /FEA=mRNA /GEN=APC10 /PROD=anaphase-promoting complex 10 /DB_XREF=gi:7657034 /UG=Hs.88799 anaphase-promoting complex subunit 10 /FL=gb:AL080090.1 gb:NM_014885.1 NM_014885 anaphase promoting complex subunit 10 ANAPC10 10393 NM_001256706 /// NM_001256707 /// NM_001256708 /// NM_001256709 /// NM_001256710 /// NM_001256711 /// NM_001256712 /// NM_014885 /// NR_046345 /// XM_006714058 /// XM_006714059 /// XM_006714060 /// XM_006714061 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005680 // anaphase-promoting complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement 207846_at NM_000306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000306.1 /DEF=Homo sapiens POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) (POU1F1), mRNA. /FEA=mRNA /GEN=POU1F1 /PROD=POU domain, class 1, transcription factor 1(Pit1, growth hormone factor 1) /DB_XREF=gi:4505954 /UG=Hs.89394 POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) /FL=gb:D10216.1 gb:L18781.1 gb:NM_000306.1 NM_000306 POU class 1 homeobox 1 POU1F1 5449 NM_000306 /// NM_001122757 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051169 // nuclear transport // inferred from electronic annotation /// 0060126 // somatotropin secreting cell differentiation // inferred from electronic annotation /// 0060133 // somatotropin secreting cell development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207847_s_at NM_002456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002456.1 /DEF=Homo sapiens mucin 1, transmembrane (MUC1), mRNA. /FEA=mRNA /GEN=MUC1 /PROD=mucin 1, transmembrane /DB_XREF=gi:4505282 /UG=Hs.89603 mucin 1, transmembrane /FL=gb:NM_002456.1 NM_002456 mucin 1, cell surface associated MUC1 4582 NM_001018016 /// NM_001018017 /// NM_001018021 /// NM_001044390 /// NM_001044391 /// NM_001044392 /// NM_001044393 /// NM_001204285 /// NM_001204286 /// NM_001204287 /// NM_001204288 /// NM_001204289 /// NM_001204290 /// NM_001204291 /// NM_001204292 /// NM_001204293 /// NM_001204294 /// NM_001204295 /// NM_001204296 /// NM_001204297 /// NM_002456 /// NM_182741 0001666 // response to hypoxia // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016266 // O-glycan processing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043618 // regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090240 // positive regulation of histone H4 acetylation // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 207848_at NM_000490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000490.2 /DEF=Homo sapiens arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) (AVP), mRNA. /FEA=mRNA /GEN=AVP /PROD=arginine vasopressin-neurophysin IIpreproprotein /DB_XREF=gi:13259532 /UG=Hs.89648 arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) /FL=gb:NM_000490.2 gb:AF031476.1 gb:M25647.1 NM_000490 arginine vasopressin AVP 551 NM_000490 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035813 // regulation of renal sodium excretion // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043084 // penile erection // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from direct assay /// 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005185 // neurohypophyseal hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from physical interaction /// 0031895 // V1B vasopressin receptor binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay 207849_at NM_000586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000586.1 /DEF=Homo sapiens interleukin 2 (IL2), mRNA. /FEA=mRNA /GEN=IL2 /PROD=interleukin 2 /DB_XREF=gi:10835148 /UG=Hs.89679 interleukin 2 /FL=gb:NM_000586.1 gb:U25676.1 gb:S77834.1 NM_000586 interleukin 2 IL2 3558 NM_000586 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030101 // natural killer cell activation // traceable author statement /// 0030217 // T cell differentiation // traceable author statement /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // traceable author statement /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046013 // regulation of T cell homeostatic proliferation // inferred from electronic annotation /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0051024 // positive regulation of immunoglobulin secretion // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005125 // cytokine activity // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // traceable author statement /// 0008083 // growth factor activity // traceable author statement /// 0019209 // kinase activator activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0031851 // kappa-type opioid receptor binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 207850_at NM_002090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002090.1 /DEF=Homo sapiens GRO3 oncogene (GRO3), mRNA. /FEA=mRNA /GEN=GRO3 /PROD=GRO3 oncogene /DB_XREF=gi:4504156 /UG=Hs.89690 GRO3 oncogene /FL=gb:M36821.1 gb:NM_002090.1 NM_002090 chemokine (C-X-C motif) ligand 3 CXCL3 2921 NM_002090 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from sequence or structural similarity 207851_s_at NM_000208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000208.1 /DEF=Homo sapiens insulin receptor (INSR), mRNA. /FEA=mRNA /GEN=INSR /PROD=insulin receptor /DB_XREF=gi:4557883 /UG=Hs.89695 insulin receptor /FL=gb:M10051.1 gb:NM_000208.1 NM_000208 insulin receptor INSR 3643 NM_000208 /// NM_001079817 /// XM_005259554 /// XM_006722743 /// XM_006722744 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019087 // transformation of host cell by virus // inferred from mutant phenotype /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046326 // positive regulation of glucose import // non-traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048639 // positive regulation of developmental growth // inferred from mutant phenotype /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005899 // insulin receptor complex // inferred from mutant phenotype /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from direct assay /// 0005009 // insulin-activated receptor activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0031995 // insulin-like growth factor II binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction /// 0051425 // PTB domain binding // inferred from physical interaction 207852_at NM_002994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002994.1 /DEF=Homo sapiens small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) (SCYB5), mRNA. /FEA=mRNA /GEN=SCYB5 /PROD=small inducible cytokine subfamily B(Cys-X-Cys), member 5 (epithelial-derivedneutrophil-activating peptide 78) /DB_XREF=gi:4506848 /UG=Hs.89714 small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) /FL=gb:NM_002994.1 NM_002994 chemokine (C-X-C motif) ligand 5 CXCL5 6374 NM_002994 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 207853_s_at NM_003085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003085.2 /DEF=Homo sapiens synuclein, beta (SNCB), mRNA. /FEA=mRNA /GEN=SNCB /PROD=beta-synuclein /DB_XREF=gi:6466453 /UG=Hs.90297 synuclein, beta /FL=gb:NM_003085.2 NM_003085 synuclein, beta SNCB 6620 NM_001001502 /// NM_003085 /// XM_006714914 /// XM_006714915 /// XM_006714916 0007268 // synaptic transmission // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 207854_at NM_002102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002102.1 /DEF=Homo sapiens glycophorin E (GYPE), mRNA. /FEA=mRNA /GEN=GYPE /PROD=glycophorin E /DB_XREF=gi:4504230 /UG=Hs.93223 glycophorin E /FL=gb:M29610.1 gb:NM_002102.1 NM_002102 glycophorin E (MNS blood group) GYPE 2996 NM_002102 /// NM_198682 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 207855_s_at NM_015127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015127.1 /DEF=Homo sapiens KIAA0761 protein (KIAA0761), mRNA. /FEA=mRNA /GEN=KIAA0761 /PROD=KIAA0761 protein /DB_XREF=gi:13194194 /UG=Hs.93121 KIAA0761 protein /FL=gb:BC002939.1 gb:NM_015127.1 NM_015127 chloride channel CLIC-like 1 CLCC1 23155 NM_001048210 /// NM_001278202 /// NM_001278203 /// NM_015127 0006821 // chloride transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005254 // chloride channel activity // inferred from electronic annotation 207856_s_at NM_017951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017951.1 /DEF=Homo sapiens hypothetical protein FLJ20297 (FLJ20297), mRNA. /FEA=mRNA /GEN=FLJ20297 /PROD=hypothetical protein FLJ20756 /DB_XREF=gi:13443032 /UG=Hs.94491 hypothetical protein FLJ20297 /FL=gb:NM_017951.1 NM_017951 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) pseudogene /// sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) LOC150776 /// SMPD4 55627 /// 150776 NM_001171083 /// NM_001171084 /// NM_017751 /// NM_017951 /// NR_026922 /// NR_033230 /// NR_033231 /// NR_033232 /// XM_005263704 /// XM_006712625 0006665 // sphingolipid metabolic process // traceable author statement /// 0006685 // sphingomyelin catabolic process // inferred from direct assay /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046475 // glycerophospholipid catabolic process // inferred from direct assay /// 0046513 // ceramide biosynthetic process // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004767 // sphingomyelin phosphodiesterase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050290 // sphingomyelin phosphodiesterase D activity // inferred from direct assay 207857_at NM_006866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006866.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 (LILRA2), mRNA. /FEA=mRNA /GEN=LILRA2 /PROD=leukocyte immunoglobulin-like receptor,subfamily A (with TM domain), member 2 /DB_XREF=gi:5803067 /UG=Hs.94498 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 /FL=gb:U82275.1 gb:NM_006866.1 NM_006866 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 LILRA2 11027 NM_001130917 /// NM_001290270 /// NM_001290271 /// NM_006866 /// XM_005258452 /// XM_005277053 /// XM_005277231 /// XM_005278240 /// XM_006722986 /// XM_006722987 /// XM_006722988 /// XM_006722989 /// XM_006722990 /// XM_006726177 /// XM_006726178 /// XM_006726179 /// XM_006726180 /// XM_006726181 /// XM_006726182 /// XM_006726183 /// XM_006726262 /// XM_006726263 /// XM_006726264 /// XM_006726265 /// XM_006726266 /// XM_006726298 /// XM_006726299 /// XM_006726300 /// XM_006726301 /// XM_006726302 /// XM_006726303 /// XM_006726304 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207858_s_at NM_000298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000298.1 /DEF=Homo sapiens pyruvate kinase, liver and RBC (PKLR), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PKLR /PROD=pyruvate kinase, liver and RBC /DB_XREF=gi:10835120 /UG=Hs.95990 pyruvate kinase, liver and RBC /FL=gb:NM_000298.1 gb:AB015983.1 NM_000298 pyruvate kinase, liver and RBC PKLR 5313 NM_000298 /// NM_181871 /// XM_005245266 /// XM_006711386 /// XM_006726212 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207859_s_at NM_000749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000749.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 3 (CHRNB3), mRNA. /FEA=mRNA /GEN=CHRNB3 /PROD=cholinergic receptor, nicotinic, betapolypeptide 3 /DB_XREF=gi:4502834 /UG=Hs.96094 cholinergic receptor, nicotinic, beta polypeptide 3 /FL=gb:U62438.1 gb:NM_000749.1 NM_000749 cholinergic receptor, nicotinic, beta 3 (neuronal) CHRNB3 1142 NM_000749 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0015267 // channel activity // traceable author statement /// 0042166 // acetylcholine binding // inferred from electronic annotation 207860_at NM_004829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004829.1 /DEF=Homo sapiens lymphocyte antigen 94 (mouse) homolog (activating NK-receptor ; NK-p46) (LY94), mRNA. /FEA=mRNA /GEN=LY94 /PROD=lymphocyte antigen 94 (mouse) homolog(activating NK-receptor ; NK-p46) /DB_XREF=gi:4758691 /UG=Hs.97084 lymphocyte antigen 94 (mouse) homolog (activating NK-receptor ; NK-p46) /FL=gb:NM_004829.1 NM_004829 natural cytotoxicity triggering receptor 1 NCR1 9437 NM_001145457 /// NM_001145458 /// NM_001242356 /// NM_001242357 /// NM_004829 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0042269 // regulation of natural killer cell mediated cytotoxicity // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from sequence or structural similarity 0005057 // receptor signaling protein activity // traceable author statement 207861_at NM_002990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002990.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 22 (SCYA22), mRNA. /FEA=mRNA /GEN=SCYA22 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 22 /DB_XREF=gi:4506836 /UG=Hs.97203 small inducible cytokine subfamily A (Cys-Cys), member 22 /FL=gb:U83171.1 gb:U83239.1 gb:NM_002990.1 NM_002990 chemokine (C-C motif) ligand 22 CCL22 6367 NM_002990 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 207862_at NM_006760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006760.1 /DEF=Homo sapiens uroplakin 2 (UPK2), mRNA. /FEA=mRNA /GEN=UPK2 /PROD=uroplakin 2 /DB_XREF=gi:5803214 /UG=Hs.97234 uroplakin 2 /FL=gb:NM_006760.1 NM_006760 uroplakin 2 UPK2 7379 NM_006760 0007275 // multicellular organismal development // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0061024 // membrane organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 207863_at NM_001125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001125.1 /DEF=Homo sapiens ADP-ribosylarginine hydrolase (ADPRH), mRNA. /FEA=mRNA /GEN=ADPRH /PROD=ADP-ribosylarginine hydrolase /DB_XREF=gi:4557262 /UG=Hs.99884 ADP-ribosylarginine hydrolase /FL=gb:L13291.1 gb:NM_001125.1 NM_001125 ADP-ribosylarginine hydrolase ADPRH 141 NM_001125 /// NM_001291949 /// NM_001291950 0006464 // cellular protein modification process // inferred from mutant phenotype /// 0051725 // protein de-ADP-ribosylation // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003875 // ADP-ribosylarginine hydrolase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation 207864_at NM_002976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002976.1 /DEF=Homo sapiens sodium channel, voltage-gated, type VI, alpha polypeptide (SCN6A), mRNA. /FEA=mRNA /GEN=SCN6A /PROD=sodium channel, voltage-gated, type VI, alphapolypeptide /DB_XREF=gi:4506810 /UG=Hs.99945 sodium channel, voltage-gated, type VI, alpha polypeptide /FL=gb:M91556.1 gb:NM_002976.1 NM_002976 sodium channel, voltage-gated, type VII, alpha subunit SCN7A 6332 NM_002976 /// NR_045628 /// XM_006712680 /// XM_006712681 /// XM_006712682 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0055078 // sodium ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097386 // glial cell projection // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207865_s_at NM_001720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001720.1 /DEF=Homo sapiens bone morphogenetic protein 8 (osteogenic protein 2) (BMP8), mRNA. /FEA=mRNA /GEN=BMP8 /PROD=bone morphogenetic protein 8 precursor /DB_XREF=gi:4502428 /UG=Hs.99948 bone morphogenetic protein 8 (osteogenic protein 2) /FL=gb:M97016.1 gb:NM_001720.1 NM_001720 bone morphogenetic protein 8b BMP8B 656 NM_001720 /// XM_005271149 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 207866_at NM_001720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001720.1 /DEF=Homo sapiens bone morphogenetic protein 8 (osteogenic protein 2) (BMP8), mRNA. /FEA=mRNA /GEN=BMP8 /PROD=bone morphogenetic protein 8 precursor /DB_XREF=gi:4502428 /UG=Hs.99948 bone morphogenetic protein 8 (osteogenic protein 2) /FL=gb:M97016.1 gb:NM_001720.1 NM_001720 bone morphogenetic protein 8a BMP8A 353500 NM_181809 /// XM_006710616 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 207867_at NM_006193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006193.1 /DEF=Homo sapiens paired box gene 4 (PAX4), mRNA. /FEA=mRNA /GEN=PAX4 /PROD=paired box gene 4 /DB_XREF=gi:5453849 /UG=Hs.129706 paired box gene 4 /FL=gb:AF043978.1 gb:NM_006193.1 NM_006193 paired box 4 PAX4 5078 NM_006193 /// XM_005250397 /// XR_242243 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207868_at NM_000742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000742.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) (CHRNA2), mRNA. /FEA=mRNA /GEN=CHRNA2 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 2 (neuronal) /DB_XREF=gi:4502822 /UG=Hs.57718 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) /FL=gb:U62431.1 gb:NM_000742.1 NM_000742 cholinergic receptor, nicotinic, alpha 2 (neuronal) CHRNA2 1135 NM_000742 /// NM_001282455 /// XM_005273397 /// XM_006716282 /// XM_006716283 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred from electronic annotation 207869_s_at NM_018896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018896.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 1G subunit (CACNA1G), mRNA. /FEA=mRNA /GEN=CACNA1G /PROD=calcium channel, voltage-dependent, alpha 1Gsubunit /DB_XREF=gi:9256522 /UG=Hs.194746 calcium channel, voltage-dependent, alpha 1G subunit /FL=gb:AF134985.1 gb:NM_018896.1 NM_018896 calcium channel, voltage-dependent, T type, alpha 1G subunit CACNA1G 8913 NM_001256324 /// NM_001256325 /// NM_001256326 /// NM_001256327 /// NM_001256328 /// NM_001256329 /// NM_001256330 /// NM_001256331 /// NM_001256332 /// NM_001256333 /// NM_001256334 /// NM_001256359 /// NM_001256360 /// NM_001256361 /// NM_018896 /// NM_198376 /// NM_198377 /// NM_198378 /// NM_198379 /// NM_198380 /// NM_198382 /// NM_198383 /// NM_198384 /// NM_198385 /// NM_198386 /// NM_198387 /// NM_198388 /// NM_198396 /// NM_198397 /// NR_046054 /// NR_046055 /// NR_046056 /// NR_046057 /// NR_046058 /// XM_006722160 /// XM_006722161 0001508 // action potential // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010045 // response to nickel cation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 207870_at NM_005751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005751.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein (yotiao) 9 (AKAP9), mRNA. /FEA=mRNA /GEN=AKAP9 /PROD=A kinase (PRKA) anchor protein 9 /DB_XREF=gi:5032230 /UG=Hs.58103 A kinase (PRKA) anchor protein (yotiao) 9 /FL=gb:AF026245.1 gb:NM_005751.1 NM_005751 A kinase (PRKA) anchor protein 9 AKAP9 10142 NM_005751 /// NM_147166 /// NM_147171 /// NM_147185 /// XM_005250102 /// XM_005250103 /// XM_006715827 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 207871_s_at NM_018412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018412.2 /DEF=Homo sapiens suppression of tumorigenicity 7 (ST7), transcript variant a, mRNA. /FEA=mRNA /GEN=ST7 /PROD=suppression of tumorigenicity 7, isoform a /DB_XREF=gi:11761623 /UG=Hs.5814 suppression of tumorigenicity 7 /FL=gb:NM_018412.2 gb:AF234882.1 NM_018412 microRNA 6132 /// suppression of tumorigenicity 7 /// ST7 overlapping transcript 3 MIR6132 /// ST7 /// ST7-OT3 7982 /// 93655 /// 102466616 NM_018412 /// NM_021908 /// NR_002332 /// NR_106748 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 207872_s_at NM_006863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006863.1 /DEF=Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 (LILRA1), mRNA. /FEA=mRNA /GEN=LILRA1 /PROD=leukocyte immunoglobulin-like receptor,subfamily A (with TM domain), member 1 /DB_XREF=gi:5803065 /UG=Hs.166156 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 /FL=gb:AF025530.1 gb:NM_006863.1 NM_006863 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 LILRA1 11024 NM_001278318 /// NM_001278319 /// NM_006863 /// NR_103501 /// NR_103502 /// NR_103503 /// XM_006722979 /// XM_006722980 /// XM_006722981 /// XM_006722982 /// XM_006726171 /// XM_006726172 /// XM_006726173 /// XM_006726174 /// XM_006726258 /// XM_006726259 /// XM_006726260 /// XM_006726261 /// XM_006726294 /// XM_006726295 /// XM_006726296 /// XM_006726297 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 207873_x_at NM_021115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021115.1 /DEF=Homo sapiens seizure related gene 6 (mouse)-like (SEZ6L), mRNA. /FEA=mRNA /GEN=SEZ6L /PROD=seizure related gene 6 (mouse)-like /DB_XREF=gi:10863914 /UG=Hs.194766 seizure related gene 6 (mouse)-like /FL=gb:NM_021115.1 NM_021115 seizure related 6 homolog (mouse)-like SEZ6L 23544 NM_001184773 /// NM_001184774 /// NM_001184775 /// NM_001184776 /// NM_001184777 /// NM_021115 /// XM_005261439 /// XM_005261440 /// XM_006724195 /// XM_006724196 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 207874_s_at NM_006684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006684.1 /DEF=Homo sapiens complement factor H-related 4 (FHR-4), mRNA. /FEA=mRNA /GEN=FHR-4 /PROD=complement factor H-related 4 /DB_XREF=gi:5729825 /UG=Hs.194776 complement factor H-related 4 /FL=gb:NM_006684.1 NM_006684 complement factor H-related 4 CFHR4 10877 NM_001201550 /// NM_001201551 /// NM_006684 /// XM_006711128 /// XM_006711129 /// XM_006711130 /// XM_006711131 /// XM_006711132 /// XM_006711133 /// XM_006711134 0006869 // lipid transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005319 // lipid transporter activity // traceable author statement 207875_at NM_015882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015882.1 /DEF=Homo sapiens RIG-like 5-6 (LOC51048), mRNA. /FEA=mRNA /GEN=LOC51048 /PROD=RIG-like 5-6 /DB_XREF=gi:7705671 /UG=Hs.166175 RIG-like 5-6 /FL=gb:AF034209.1 gb:NM_015882.1 NM_015882 207876_s_at NM_001458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001458.1 /DEF=Homo sapiens filamin C, gamma (actin-binding protein-280) (FLNC), mRNA. /FEA=mRNA /GEN=FLNC /PROD=gamma filamin /DB_XREF=gi:4557596 /UG=Hs.58414 filamin C, gamma (actin-binding protein-280) /FL=gb:AF089841.1 gb:NM_001458.1 NM_001458 filamin C, gamma FLNC 2318 NM_001127487 /// NM_001458 /// XM_006715910 0034329 // cell junction assembly // traceable author statement /// 0048747 // muscle fiber development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016528 // sarcoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from physical interaction 207877_s_at NM_002533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002533.1 /DEF=Homo sapiens nuclear VCP-like (NVL), mRNA. /FEA=mRNA /GEN=NVL /PROD=nuclear VCP-like /DB_XREF=gi:4505482 /UG=Hs.58927 nuclear VCP-like /FL=gb:U78772.1 gb:NM_002533.1 NM_002533 nuclear VCP-like NVL 4931 NM_001243146 /// NM_001243147 /// NM_002533 /// NM_206840 /// XM_006711772 /// XM_006711773 /// XM_006711774 /// XM_006711775 /// XM_006711776 /// XM_006711777 /// XM_006711778 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 207878_at NM_015848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015848.1 /DEF=Homo sapiens cytokeratin 2 (HUMCYT2A), mRNA. /FEA=mRNA /GEN=HUMCYT2A /PROD=cytokeratin 2 /DB_XREF=gi:7705544 /UG=Hs.166189 cytokeratin 2 /FL=gb:M99063.1 gb:NM_015848.1 NM_015848 keratin 76 KRT76 51350 NM_015848 0007010 // cytoskeleton organization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 207879_at NM_001691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001691.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 2 (ATP6A2), mRNA. /FEA=mRNA /GEN=ATP6A2 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), alpha polypeptide, 70kD, isoform 2 /DB_XREF=gi:4502306 /UG=Hs.603 ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 2 /FL=gb:L09234.1 gb:NM_001691.1 NM_001691 207880_at NM_002390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002390.2 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 11 (ADAM11), transcript variant 1, mRNA. /FEA=mRNA /GEN=ADAM11 /PROD=a disintegrin and metalloprotease domain 11,isoform 1 preproprotein /DB_XREF=gi:4585709 /UG=Hs.6088 a disintegrin and metalloproteinase domain 11 /FL=gb:NM_021612.1 gb:AB009675.1 gb:NM_002390.2 NM_002390 ADAM metallopeptidase domain 11 ADAM11 4185 NM_002390 /// XM_005257373 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 207881_at NM_015887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015887.1 /DEF=Homo sapiens putative peroxisome microbody protein 175.1 (LOC51051), mRNA. /FEA=mRNA /GEN=LOC51051 /PROD=putative peroxisome microbody protein 175.1 /DB_XREF=gi:7705677 /UG=Hs.166197 putative peroxisome microbody protein 175.1 /FL=gb:AF050199.1 gb:NM_015887.1 NM_015887 207882_at NM_017532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017532.1 /DEF=Homo sapiens p65 protein (HSAJ2425), mRNA. /FEA=mRNA /GEN=HSAJ2425 /PROD=p65 protein /DB_XREF=gi:8923776 /UG=Hs.194790 p65 protein /FL=gb:NM_017532.1 NM_017532 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207883_s_at NM_003227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003227.1 /DEF=Homo sapiens transferrin receptor 2 (TFR2), mRNA. /FEA=mRNA /GEN=TFR2 /PROD=transferrin receptor 2 /DB_XREF=gi:4507454 /UG=Hs.63758 transferrin receptor 2 /FL=gb:NM_003227.1 NM_003227 transferrin receptor 2 TFR2 7036 NM_001206855 /// NM_003227 /// XM_005250553 /// XM_005250554 /// XM_006716103 0006508 // proteolysis // inferred from electronic annotation /// 0006826 // iron ion transport // non-traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004998 // transferrin receptor activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation 207884_at NM_000180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000180.1 /DEF=Homo sapiens guanylate cyclase 2D, membrane (retina-specific) (GUCY2D), mRNA. /FEA=mRNA /GEN=GUCY2D /PROD=guanylate cyclase 2D, membrane(retina-specific) /DB_XREF=gi:4504216 /UG=Hs.1974 guanylate cyclase 2D, membrane (retina-specific) /FL=gb:NM_000180.1 gb:M92432.1 NM_000180 guanylate cyclase 2D, membrane (retina-specific) GUCY2D 3000 NM_000180 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007168 // receptor guanylyl cyclase signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005640 // nuclear outer membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 207885_at NM_004057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004057.1 /DEF=Homo sapiens calbindin 3, (vitamin D-dependent calcium-binding protein) (CALB3), mRNA. /FEA=mRNA /GEN=CALB3 /PROD=calbindin 3 /DB_XREF=gi:4757897 /UG=Hs.639 calbindin 3, (vitamin D-dependent calcium-binding protein) /FL=gb:L13220.1 gb:NM_004057.1 NM_004057 S100 calcium binding protein G S100G 795 NM_004057 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005499 // vitamin D binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207886_s_at NM_001742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001742.1 /DEF=Homo sapiens calcitonin receptor (CALCR), mRNA. /FEA=mRNA /GEN=CALCR /PROD=calcitonin receptor /DB_XREF=gi:4502546 /UG=Hs.640 calcitonin receptor /FL=gb:U26553.1 gb:U26554.1 gb:NM_001742.1 gb:AB022177.1 NM_001742 calcitonin receptor CALCR 799 NM_001164737 /// NM_001164738 /// NM_001742 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0015031 // protein transport // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004948 // calcitonin receptor activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay /// 0032841 // calcitonin binding // inferred from direct assay /// 0032841 // calcitonin binding // inferred from physical interaction 207887_s_at AB022177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB022177.1 /DEF=Homo sapiens mRNA for calcitonin receptor, complete cds, isolate from breast carcinoma. /FEA=mRNA /PROD=calcitonin receptor /DB_XREF=gi:6456429 /UG=Hs.640 calcitonin receptor /FL=gb:U26553.1 gb:U26554.1 gb:NM_001742.1 gb:AB022177.1 AB022177 calcitonin receptor CALCR 799 NM_001164737 /// NM_001164738 /// NM_001742 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0015031 // protein transport // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004948 // calcitonin receptor activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay /// 0032841 // calcitonin binding // inferred from direct assay /// 0032841 // calcitonin binding // inferred from physical interaction 207888_at NM_004940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004940.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 7 (RNA helicase, 52kD) (DDX7), mRNA. /FEA=mRNA /GEN=DDX7 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 7 /DB_XREF=gi:4826687 /UG=Hs.123058 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 7 (RNA helicase, 52kD) /FL=gb:D26528.1 gb:NM_004940.1 NM_004940 207889_at NM_007101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007101.1 /DEF=Homo sapiens sarcosine dehydrogenase (SARDH), mRNA. /FEA=mRNA /GEN=SARDH /PROD=sarcosine dehydrogenase /DB_XREF=gi:6005867 /UG=Hs.198003 sarcosine dehydrogenase /FL=gb:AF095737.2 gb:NM_007101.1 NM_007101 sarcosine dehydrogenase SARDH 1757 NM_001134707 /// NM_007101 /// XM_005272170 /// XM_006716990 /// XM_006716991 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008480 // sarcosine dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 207890_s_at NM_022718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022718.1 /DEF=Homo sapiens matrix metalloproteinase 25 (MMP25), transcript variant 2, mRNA. /FEA=mRNA /GEN=MMP25 /PROD=matrix metalloproteinase 25 preproprotein /DB_XREF=gi:13027808 /UG=Hs.198265 matrix metalloproteinase 25 /FL=gb:NM_022718.1 NM_022718 matrix metallopeptidase 25 MMP25 64386 NM_004142 /// NM_022468 /// NM_022718 0006508 // proteolysis // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0060022 // hard palate development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207891_s_at NM_017518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017518.2 /DEF=Homo sapiens Xq28, 2000bp sequence contg. ORF (HSXQ28ORF), mRNA. /FEA=mRNA /GEN=HSXQ28ORF /PROD=Xq28, 2000bp sequence contg. ORF /DB_XREF=gi:11120679 /UG=Hs.6487 Xq28, 2000bp sequence contg. ORF /FL=gb:NM_017518.2 gb:AF267739.1 NM_017518 HAUS augmin-like complex, subunit 7 /// three prime repair exonuclease 2 HAUS7 /// TREX2 11219 /// 55559 NM_017518 /// NM_080699 /// NM_080700 /// NM_080701 /// NM_207106 /// NM_207107 /// NR_073156 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070652 // HAUS complex // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008296 // 3'-5'-exodeoxyribonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 207892_at NM_000074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000074.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) (TNFSF5), mRNA. /FEA=mRNA /GEN=TNFSF5 /PROD=CD40 antigen ligand /DB_XREF=gi:4557432 /UG=Hs.652 tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) /FL=gb:L07414.1 gb:NM_000074.1 NM_000074 CD40 ligand CD40LG 959 NM_000074 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0030168 // platelet activation // inferred from direct assay /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0048305 // immunoglobulin secretion // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005174 // CD40 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 207893_at NM_003140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003140.1 /DEF=Homo sapiens sex determining region Y (SRY), mRNA. /FEA=mRNA /GEN=SRY /PROD=sex determining region Y /DB_XREF=gi:4507224 /UG=Hs.1992 sex determining region Y /FL=gb:L10101.1 gb:NM_003140.1 NM_003140 sex determining region Y SRY 6736 NM_003140 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007530 // sex determination // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030238 // male sex determination // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000020 // positive regulation of male gonad development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from electronic annotation 207894_s_at NM_020552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020552.1 /DEF=Homo sapiens T-cell leukemialymphoma 6 (TCL6), transcript variant TCL6b1, mRNA. /FEA=mRNA /GEN=TCL6 /PROD=T-cell leukemialymphoma 6, isoform TCL6b1 /DB_XREF=gi:10947111 /UG=Hs.144519 T-cell leukemialymphoma 6 /FL=gb:NM_020552.1 gb:AB035335.1 NM_020552 T-cell leukemia/lymphoma 6 (non-protein coding) TCL6 27004 NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NR_028288 207895_at NM_005468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005468.1 /DEF=Homo sapiens N-acetylated alpha-linked acidic dipeptidase-like; ILEAL DIPEPTIDYLPEPTIDASE (NAALADASEL), mRNA. /FEA=mRNA /GEN=NAALADASEL /PROD=N-acetylated alpha-linked acidicdipeptidase-like; ILEAL DIPEPTIDYLPEPTIDASE /DB_XREF=gi:4885506 /UG=Hs.199293 N-acetylated alpha-linked acidic dipeptidase-like; ILEAL DIPEPTIDYLPEPTIDASE /FL=gb:NM_005468.1 NM_005468 N-acetylated alpha-linked acidic dipeptidase-like 1 NAALADL1 10004 NM_005468 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207896_s_at NM_007337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007337.1 /DEF=Homo sapiens deleted in lung and esophageal cancer 1 (DLEC1), transcript variant DLEC1-S3, mRNA. /FEA=mRNA /GEN=DLEC1 /PROD=deleted in lung and esophageal cancer 1, isoformDLEC1-S3 /DB_XREF=gi:6715594 /UG=Hs.200188 deleted in lung and esophageal cancer 1 /FL=gb:NM_007337.1 NM_007337 deleted in lung and esophageal cancer 1 DLEC1 9940 NM_007335 /// NM_007336 /// NM_007337 /// NM_007338 /// XM_005265630 /// XM_005265631 /// XM_006713437 /// XM_006713438 /// XM_006713439 /// XM_006713440 /// XM_006713441 /// XR_427301 /// XR_427302 0008285 // negative regulation of cell proliferation // traceable author statement 0005737 // cytoplasm // inferred from direct assay 207897_at NM_001883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001883.1 /DEF=Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), mRNA. /FEA=mRNA /GEN=CRHR2 /PROD=corticotropin releasing hormone receptor 2 /DB_XREF=gi:4503044 /UG=Hs.66578 corticotropin releasing hormone receptor 2 /FL=gb:U34587.1 gb:NM_001883.1 NM_001883 corticotropin releasing hormone receptor 2 CRHR2 1395 NM_001202475 /// NM_001202481 /// NM_001202482 /// NM_001202483 /// NM_001883 /// XM_006715651 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0071376 // cellular response to corticotropin-releasing hormone stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015056 // corticotrophin-releasing factor receptor activity // inferred from electronic annotation 207899_at NM_004123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004123.1 /DEF=Homo sapiens gastric inhibitory polypeptide (GIP), mRNA. /FEA=mRNA /GEN=GIP /PROD=gastric inhibitory polypeptide /DB_XREF=gi:4758435 /UG=Hs.1454 gastric inhibitory polypeptide /FL=gb:M18185.1 gb:NM_004123.1 NM_004123 gastric inhibitory polypeptide GIP 2695 NM_004123 0001101 // response to acid // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035640 // exploration behavior // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0055123 // digestive system development // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0070094 // positive regulation of glucagon secretion // inferred from electronic annotation /// 0070328 // triglyceride homeostasis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation 207900_at NM_002987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002987.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 17 (SCYA17), mRNA. /FEA=mRNA /GEN=SCYA17 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 17 /DB_XREF=gi:4506828 /UG=Hs.66742 small inducible cytokine subfamily A (Cys-Cys), member 17 /FL=gb:D43767.1 gb:NM_002987.1 NM_002987 chemokine (C-C motif) ligand 17 CCL17 6361 NM_002987 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0031729 // CCR4 chemokine receptor binding // inferred from electronic annotation 207901_at NM_002187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002187.1 /DEF=Homo sapiens interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (IL12B), mRNA. /FEA=mRNA /GEN=IL12B /PROD=interleukin 12B /DB_XREF=gi:4504640 /UG=Hs.674 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) /FL=gb:M65272.1 gb:M65290.1 gb:NM_002187.1 gb:AF180563.1 NM_002187 interleukin 12B IL12B 3593 NM_002187 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002323 // natural killer cell activation involved in immune response // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019953 // sexual reproduction // traceable author statement /// 0030101 // natural killer cell activation // inferred from direct assay /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032700 // negative regulation of interleukin-17 production // inferred from direct assay /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032816 // positive regulation of natural killer cell activation // inferred from direct assay /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from mutant phenotype /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0042035 // regulation of cytokine biosynthetic process // traceable author statement /// 0042088 // T-helper 1 type immune response // traceable author statement /// 0042093 // T-helper cell differentiation // inferred from direct assay /// 0042095 // interferon-gamma biosynthetic process // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045078 // positive regulation of interferon-gamma biosynthetic process // traceable author statement /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050671 // positive regulation of lymphocyte proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043514 // interleukin-12 complex // inferred from direct assay /// 0070743 // interleukin-23 complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005143 // interleukin-12 receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0042164 // interleukin-12 alpha subunit binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045519 // interleukin-23 receptor binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 207902_at NM_000564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000564.1 /DEF=Homo sapiens interleukin 5 receptor, alpha (IL5RA), mRNA. /FEA=mRNA /GEN=IL5RA /PROD=interleukin 5 receptor, alpha /DB_XREF=gi:10835130 /UG=Hs.68876 interleukin 5 receptor, alpha /FL=gb:NM_000564.1 gb:M96652.1 NM_000564 interleukin 5 receptor, alpha IL5RA 3568 NM_000564 /// NM_001243099 /// NM_175724 /// NM_175725 /// NM_175726 /// NM_175727 /// NM_175728 /// XM_006713127 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032674 // regulation of interleukin-5 production // inferred from electronic annotation /// 0038043 // interleukin-5-mediated signaling pathway // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005895 // interleukin-5 receptor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004914 // interleukin-5 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 207904_s_at NM_005575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005575.1 /DEF=Homo sapiens leucylcystinyl aminopeptidase (LNPEP), mRNA. /FEA=mRNA /GEN=LNPEP /PROD=leucylcystinyl aminopeptidase /DB_XREF=gi:5031880 /UG=Hs.166733 leucylcystinyl aminopeptidase /FL=gb:D50810.1 gb:U62768.1 gb:NM_005575.1 NM_005575 leucyl/cystinyl aminopeptidase LNPEP 4012 NM_005575 /// NM_175920 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031905 // early endosome lumen // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004177 // aminopeptidase activity // not recorded /// 0004177 // aminopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207906_at NM_000588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000588.1 /DEF=Homo sapiens interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA. /FEA=mRNA /GEN=IL3 /PROD=interleukin 3 (colony-stimulating factor,multiple) /DB_XREF=gi:4504666 /UG=Hs.694 interleukin 3 (colony-stimulating factor, multiple) /FL=gb:M17115.1 gb:M14743.1 gb:M20137.1 gb:NM_000588.1 NM_000588 interleukin 3 IL3 3562 NM_000588 0006955 // immune response // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0035162 // embryonic hemopoiesis // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0005135 // interleukin-3 receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 207907_at NM_003807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003807.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14), mRNA. /FEA=mRNA /GEN=TNFSF14 /PROD=tumor necrosis factor (ligand) superfamily,member 14 /DB_XREF=gi:4507600 /UG=Hs.129708 tumor necrosis factor (ligand) superfamily, member 14 /FL=gb:AF036581.1 gb:AF064090.1 gb:NM_003807.1 NM_003807 tumor necrosis factor (ligand) superfamily, member 14 TNFSF14 8740 NM_003807 /// NM_172014 /// XM_005259670 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008588 // release of cytoplasmic sequestered NF-kappaB // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042098 // T cell proliferation // non-traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043029 // T cell homeostasis // non-traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay 207908_at NM_000423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000423.1 /DEF=Homo sapiens keratin 2A (epidermal ichthyosis bullosa of Siemens) (KRT2A), mRNA. /FEA=mRNA /GEN=KRT2A /PROD=keratin 2a /DB_XREF=gi:4557702 /UG=Hs.707 keratin 2A (epidermal ichthyosis bullosa of Siemens) /FL=gb:M99061.1 gb:NM_000423.1 NM_000423 keratin 2 KRT2 3849 NM_000423 0008544 // epidermis development // traceable author statement /// 0031424 // keratinization // inferred from direct assay /// 0032980 // keratinocyte activation // inferred from direct assay /// 0043616 // keratinocyte proliferation // inferred from direct assay /// 0051546 // keratinocyte migration // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005882 // intermediate filament // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 207909_x_at U21663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U21663.1 /DEF=Human deleted in azoospermia protein (DAZ) mRNA, complete cds. /FEA=mRNA /GEN=DAZ /PROD=DAZ protein /DB_XREF=gi:1045307 /UG=Hs.70936 deleted in azoospermia /FL=gb:U21663.1 gb:NM_004081.2 U21663 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 207910_at NM_006552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006552.1 /DEF=Homo sapiens lipophilin A (uteroglobin family member) (LPHA), mRNA. /FEA=mRNA /GEN=LPHA /PROD=lipophilin A precursor /DB_XREF=gi:5729906 /UG=Hs.202686 lipophilin A (uteroglobin family member) /FL=gb:NM_006552.1 NM_006552 secretoglobin, family 1D, member 1 SCGB1D1 10648 NM_006552 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0046982 // protein heterodimerization activity // inferred from direct assay 207911_s_at NM_004245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004245.1 /DEF=Homo sapiens transglutaminase 5 (TGM5), mRNA. /FEA=mRNA /GEN=TGM5 /PROD=transglutaminase 5 /DB_XREF=gi:4759229 /UG=Hs.129719 transglutaminase 5 /FL=gb:AF035961.1 gb:NM_004245.1 NM_004245 transglutaminase 5 TGM5 9333 NM_004245 /// NM_201631 0006464 // cellular protein modification process // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207912_s_at NM_004081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004081.2 /DEF=Homo sapiens deleted in azoospermia (DAZ), mRNA. /FEA=mRNA /GEN=DAZ /PROD=deleted in azoospermia /DB_XREF=gi:6552325 /UG=Hs.70936 deleted in azoospermia /FL=gb:U21663.1 gb:NM_004081.2 NM_004081 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 207913_at NM_000774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000774.1 /DEF=Homo sapiens cytochrome P450, subfamily IIF, polypeptide 1 (CYP2F1), mRNA. /FEA=mRNA /GEN=CYP2F1 /PROD=cytochrome P450, subfamily IIF, polypeptide 1 /DB_XREF=gi:4503224 /UG=Hs.72913 cytochrome P450, subfamily IIF, polypeptide 1 /FL=gb:J02906.1 gb:NM_000774.1 NM_000774 cytochrome P450, family 2, subfamily F, polypeptide 1 CYP2F1 1572 NM_000774 /// XM_006723052 /// XM_006723053 /// XR_430190 /// XR_430191 0006805 // xenobiotic metabolic process // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0018931 // naphthalene metabolic process // inferred from direct assay /// 0018979 // trichloroethylene metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 207914_x_at NM_001989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001989.1 /DEF=Homo sapiens even-skipped homeo box 1 (homolog of Drosophila) (EVX1), mRNA. /FEA=mRNA /GEN=EVX1 /PROD=even-skipped homeo box 1 (homolog ofDrosophila) /DB_XREF=gi:4503614 /UG=Hs.167074 even-skipped homeo box 1 (homolog of Drosophila) /FL=gb:NM_001989.1 NM_001989 even-skipped homeobox 1 EVX1 2128 NM_001989 /// XM_005249639 /// XM_005249640 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0021913 // regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 207915_at NM_005377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005377.1 /DEF=Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog 2 (MYCL2), mRNA. /FEA=mRNA /GEN=MYCL2 /PROD=v-myc avian myelocytomatosis viral oncogenehomolog 2 /DB_XREF=gi:4885498 /UG=Hs.72931 v-myc avian myelocytomatosis viral oncogene homolog 2 /FL=gb:NM_005377.1 NM_005377 MYCL pseudogene 1 /// MYCLP1 /// MYCLP1 207916_at NM_005405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005405.1 /DEF=Homo sapiens RNA binding motif protein, Y chromosome, family 2, member B (RBMY2B) mRNA. /FEA=mRNA /GEN=RBMY2B /PROD=RNA binding motif protein, Y chromosome, family2, member B /DB_XREF=gi:4885576 /UG=Hs.72966 RNA binding motif protein, Y chromosome, family 2, member B /FL=gb:NM_005405.1 NM_005405 /// /// RNA binding motif protein, Y-linked, family 2, member A pseudogene /// /// RNA binding motif protein, Y-linked, family 2, member B pseudogene /// /// RNA binding motif protein, Y-linked, family 2, member D pseudogene AC009947.3 /// RBMY2AP /// RBMY2AP /// RBMY2BP /// RBMY2BP /// RBMY2DP /// RBMY2DP 207917_at NM_015901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015901.1 /DEF=Homo sapiens unknown (LOC51055), mRNA. /FEA=mRNA /GEN=LOC51055 /PROD=unknown /DB_XREF=gi:7705685 /UG=Hs.202694 unknown /FL=gb:U88048.1 gb:NM_015901.1 NM_015901 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207918_s_at NM_003308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003308.2 /DEF=Homo sapiens testis specific protein, Y-linked (TSPY), mRNA. /FEA=mRNA /GEN=TSPY /PROD=testis specific protein, Y-linked /DB_XREF=gi:13324673 /UG=Hs.2051 testis specific protein, Y-linked /FL=gb:NM_003308.2 gb:U58096.1 gb:M98525.1 NM_003308 testis specific protein, Y-linked 1 /// testis specific protein, Y-linked 10 /// testis specific protein, Y-linked 3 /// testis specific protein, Y-linked 4 /// testis specific protein, Y-linked 8 TSPY1 /// TSPY10 /// TSPY3 /// TSPY4 /// TSPY8 7258 /// 728137 /// 728395 /// 728403 /// 100289087 NM_001077697 /// NM_001164471 /// NM_001197242 /// NM_001243721 /// NM_001282469 /// NM_003308 /// XM_002344198 /// XM_005272742 /// XM_005272743 /// XM_005272744 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007506 // gonadal mesoderm development // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 207919_at NM_004314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004314.1 /DEF=Homo sapiens ADP-ribosyltransferase 1 (ART1), mRNA. /FEA=mRNA /GEN=ART1 /PROD=ADP-ribosyltransferase 1 /DB_XREF=gi:4757783 /UG=Hs.73139 ADP-ribosyltransferase 1 /FL=gb:NM_004314.1 NM_004314 ADP-ribosyltransferase 1 ART1 417 NM_004314 /// XM_005252933 /// XM_006718236 /// XM_006718237 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0003956 // NAD(P)+-protein-arginine ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 207920_x_at NM_003410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003410.1 /DEF=Homo sapiens zinc finger protein, X-linked (ZFX), mRNA. /FEA=mRNA /GEN=ZFX /PROD=zinc finger protein, X-linked /DB_XREF=gi:4507964 /UG=Hs.2074 zinc finger protein, X-linked /FL=gb:M30608.1 gb:NM_003410.1 NM_003410 zinc finger protein, X-linked ZFX 7543 NM_001178084 /// NM_001178085 /// NM_001178086 /// NM_001178095 /// NM_003410 /// XM_005274591 /// XM_005274592 /// XM_005274594 /// XM_006724513 /// XM_006724514 /// XM_006724515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060746 // parental behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207921_x_at NM_013952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013952.1 /DEF=Homo sapiens paired box gene 8 (PAX8), transcript variant PAX8C, mRNA. /FEA=mRNA /GEN=PAX8 /PROD=paired box gene 8, isoform PAX8C /DB_XREF=gi:7524362 /UG=Hs.73149 paired box gene 8 /FL=gb:NM_013952.1 NM_013952 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 207922_s_at NM_005882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005882.2 /DEF=Homo sapiens macrophage erythroblast attacher (MAEA), mRNA. /FEA=mRNA /GEN=MAEA /PROD=erythroblast macrophage attacher /DB_XREF=gi:9257203 /UG=Hs.20815 macrophage erythroblast attacher /FL=gb:AF084928.1 gb:NM_005882.2 NM_005882 uncharacterized LOC101928676 /// macrophage erythroblast attacher LOC101928676 /// MAEA 10296 /// 101928676 NM_001017405 /// NM_001297430 /// NM_001297431 /// NM_001297432 /// NM_001297433 /// NM_005882 /// NR_123716 /// XM_005272243 /// XM_005272247 /// XM_006713849 /// XM_006713850 /// XM_006713851 /// XR_246617 /// XR_249558 /// XR_251539 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007346 // regulation of mitotic cell cycle // non-traceable author statement /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from direct assay /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0048822 // enucleate erythrocyte development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005826 // actomyosin contractile ring // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 207923_x_at NM_013953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013953.1 /DEF=Homo sapiens paired box gene 8 (PAX8), transcript variant PAX8D, mRNA. /FEA=mRNA /GEN=PAX8 /PROD=paired box gene 8, isoform PAX8D /DB_XREF=gi:7524364 /UG=Hs.73149 paired box gene 8 /FL=gb:NM_013953.1 NM_013953 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 207924_x_at NM_013992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013992.1 /DEF=Homo sapiens paired box gene 8 (PAX8), transcript variant PAX8E, mRNA. /FEA=mRNA /GEN=PAX8 /PROD=paired box gene 8, isoform PAX8E /DB_XREF=gi:7669541 /UG=Hs.73149 paired box gene 8 /FL=gb:NM_013992.1 NM_013992 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 207925_at NM_001900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001900.1 /DEF=Homo sapiens cystatin D (CST5), mRNA. /FEA=mRNA /GEN=CST5 /PROD=cystatin D /DB_XREF=gi:4503110 /UG=Hs.121489 cystatin D /FL=gb:NM_001900.1 NM_001900 cystatin D CST5 1473 NM_001900 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207926_at NM_004488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004488.1 /DEF=Homo sapiens glycoprotein V (platelet) (GP5), mRNA. /FEA=mRNA /GEN=GP5 /PROD=glycoprotein V (platelet) /DB_XREF=gi:4758459 /UG=Hs.73734 glycoprotein V (platelet) /FL=gb:NM_004488.1 NM_004488 glycoprotein V (platelet) GP5 2814 NM_004488 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation 207927_at NM_019859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019859.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) (HTR7), transcript variant d, mRNA. /FEA=mRNA /GEN=HTR7 /PROD=5-hydroxytryptamine receptor 7, isoform d /DB_XREF=gi:10880128 /UG=Hs.73739 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) /FL=gb:NM_019859.1 gb:U68488.1 NM_019859 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled HTR7 3363 NM_000872 /// NM_019859 /// NM_019860 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0042310 // vasoconstriction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 207928_s_at NM_006529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006529.1 /DEF=Homo sapiens glycine receptor, alpha 3 (GLRA3), mRNA. /FEA=mRNA /GEN=GLRA3 /PROD=glycine receptor, alpha 3 /DB_XREF=gi:5729843 /UG=Hs.167742 glycine receptor, alpha 3 /FL=gb:NM_006529.1 NM_006529 glycine receptor, alpha 3 GLRA3 8001 NM_001042543 /// NM_006529 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016935 // glycine-gated chloride channel complex // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // non-traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from electronic annotation /// 0022824 // transmitter-gated ion channel activity // inferred from electronic annotation /// 0030594 // neurotransmitter receptor activity // non-traceable author statement 207929_at NM_005314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005314.1 /DEF=Homo sapiens gastrin-releasing peptide receptor (GRPR), mRNA. /FEA=mRNA /GEN=GRPR /PROD=gastrin-releasing peptide receptor /DB_XREF=gi:4885360 /UG=Hs.73883 gastrin-releasing peptide receptor /FL=gb:M73481.1 gb:NM_005314.1 NM_005314 gastrin-releasing peptide receptor GRPR 2925 NM_005314 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031989 // bombesin receptor signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004946 // bombesin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // traceable author statement 207930_at NM_002297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002297.1 /DEF=Homo sapiens lipocalin 1 (protein migrating faster than albumin, tear prealbumin) (LCN1), mRNA. /FEA=mRNA /GEN=LCN1 /PROD=lipocalin 1 (protein migrating faster thanalbumin, tear prealbumin) /DB_XREF=gi:4504962 /UG=Hs.2099 lipocalin 1 (protein migrating faster than albumin, tear prealbumin) /FL=gb:NM_002297.1 gb:M90424.1 NM_002297 lipocalin 1 LCN1 3933 NM_001252617 /// NM_001252618 /// NM_001252619 /// NM_002297 0001895 // retina homeostasis // inferred from expression pattern /// 0006508 // proteolysis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // traceable author statement 207931_s_at NM_006212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006212.1 /DEF=Homo sapiens 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 2 (PFKFB2), mRNA. /FEA=mRNA /GEN=PFKFB2 /PROD=6-phosphofructo-2-kinasefructose-2,6-biphosphatase 2 /DB_XREF=gi:5453877 /UG=Hs.211585 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 2 /FL=gb:NM_006212.1 NM_006212 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 PFKFB2 5208 NM_001018053 /// NM_006212 /// XM_005273162 /// XM_006711381 /// XM_006711382 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from direct assay /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 207932_at NM_002170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002170.1 /DEF=Homo sapiens interferon, alpha 8 (IFNA8), mRNA. /FEA=mRNA /GEN=IFNA8 /PROD=interferon, alpha 8 /DB_XREF=gi:4504598 /UG=Hs.73890 interferon, alpha 8 /FL=gb:K01900.1 gb:NM_002170.1 NM_002170 interferon, alpha 8 IFNA8 3445 NM_002170 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 207933_at NM_003460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003460.1 /DEF=Homo sapiens zona pellucida glycoprotein 2 (sperm receptor) (ZP2), mRNA. /FEA=mRNA /GEN=ZP2 /PROD=zona pellucida glycoprotein 2 (sperm receptor) /DB_XREF=gi:4508044 /UG=Hs.73982 zona pellucida glycoprotein 2 (sperm receptor) /FL=gb:M90366.1 gb:NM_003460.1 NM_003460 zona pellucida glycoprotein 2 (sperm receptor) ZP2 7783 NM_001290104 /// NM_003460 /// XM_005255562 /// XM_006721090 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from sequence or structural similarity /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement /// 0060046 // regulation of acrosome reaction // inferred from direct assay /// 0060468 // prevention of polyspermy // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0015026 // coreceptor activity // traceable author statement /// 0032190 // acrosin binding // inferred from physical interaction 207934_at NM_021026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021026.1 /DEF=Homo sapiens ret finger protein-like 1 (RFPL1), mRNA. /FEA=mRNA /GEN=RFPL1 /PROD=ret finger protein-like 1 /DB_XREF=gi:10440557 /UG=Hs.167750 ret finger protein-like 1 /FL=gb:NM_021026.1 NM_021026 ret finger protein-like 1 RFPL1 5988 NM_021026 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207935_s_at NM_002274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002274.1 /DEF=Homo sapiens keratin 13 (KRT13), mRNA. /FEA=mRNA /GEN=KRT13 /PROD=keratin 13 /DB_XREF=gi:4504910 /UG=Hs.74070 keratin 13 /FL=gb:NM_002274.1 NM_002274 keratin 13 KRT13 3860 NM_002274 /// NM_153490 0007010 // cytoskeleton organization // inferred from direct assay /// 0008544 // epidermis development // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0043587 // tongue morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 207936_x_at NM_006604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006604.1 /DEF=Homo sapiens ret finger protein-like 3 (RFPL3), mRNA. /FEA=mRNA /GEN=RFPL3 /PROD=ret finger protein-like 3 /DB_XREF=gi:5730012 /UG=Hs.167751 ret finger protein-like 3 /FL=gb:NM_006604.1 NM_006604 ret finger protein-like 3 RFPL3 10738 NM_001098535 /// NM_006604 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207937_x_at NM_023110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023110.1 /DEF=Homo sapiens fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) (FGFR1), transcript variant 8, mRNA. /FEA=mRNA /GEN=FGFR1 /PROD=fibroblast growth factor receptor 1, isoform 8precursor /DB_XREF=gi:13186246 /UG=Hs.748 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) /FL=gb:NM_023110.1 NM_023110 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 207938_at NM_015886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015886.1 /DEF=Homo sapiens R3H domain (binds single-stranded nucleic acids) containing (R3HDM), mRNA. /FEA=mRNA /GEN=R3HDM /PROD=R3H domain-containing preproprotein /DB_XREF=gi:7705675 /UG=Hs.129732 R3H domain (binds single-stranded nucleic acids) containing /FL=gb:D45027.1 gb:NM_015886.1 NM_015886 peptidase inhibitor 15 PI15 51050 NM_015886 /// XM_005251255 /// XM_006716453 0010466 // negative regulation of peptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0030414 // peptidase inhibitor activity // inferred from electronic annotation 207939_x_at NM_006711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006711.1 /DEF=Homo sapiens RNA-binding protein S1, serine-rich domain (RNPS1), mRNA. /FEA=mRNA /GEN=RNPS1 /PROD=RNA-binding protein S1, serine-rich domain /DB_XREF=gi:6857825 /UG=Hs.75104 RNA-binding protein S1, serine-rich domain /FL=gb:L37368.1 gb:NM_006711.1 NM_006711 RNA binding protein S1, serine-rich domain RNPS1 10921 NM_001286625 /// NM_001286626 /// NM_001286627 /// NM_006711 /// NM_080594 /// NR_104485 /// XM_005255048 /// XM_005255049 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // traceable author statement /// 0061574 // ASAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // non-traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207940_x_at NM_001840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001840.1 /DEF=Homo sapiens cannabinoid receptor 1 (brain) (CNR1), mRNA. /FEA=mRNA /GEN=CNR1 /PROD=brain cannabinoid receptor 1 /DB_XREF=gi:4502926 /UG=Hs.75110 cannabinoid receptor 1 (brain) /FL=gb:NM_001840.1 NM_001840 cannabinoid receptor 1 (brain) CNR1 1268 NM_001160226 /// NM_001160258 /// NM_001160259 /// NM_001160260 /// NM_016083 /// NM_033181 /// XM_005248650 /// XM_006715330 0002866 // positive regulation of acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0031622 // positive regulation of fever generation // inferred from electronic annotation /// 0031999 // negative regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033004 // negative regulation of mast cell activation // inferred from electronic annotation /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038171 // cannabinoid signaling pathway // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043271 // negative regulation of ion transport // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045759 // negative regulation of action potential // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0060405 // regulation of penile erection // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004949 // cannabinoid receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from electronic annotation 207941_s_at NM_004902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004902.1 /DEF=Homo sapiens splicing factor (CC1.3) (CC1.3), mRNA. /FEA=mRNA /GEN=CC1.3 /PROD=splicing factor (CC1.3) /DB_XREF=gi:4757925 /UG=Hs.145696 splicing factor (CC1.3) /FL=gb:L10910.1 gb:NM_004902.1 NM_004902 RNA binding motif protein 39 RBM39 9584 NM_001242599 /// NM_001242600 /// NM_004902 /// NM_184234 /// NM_184237 /// NM_184241 /// NM_184244 /// NR_040722 /// NR_040723 /// NR_040724 /// XM_006723890 /// XM_006723891 /// XM_006723892 /// XM_006723893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 207943_x_at NM_006718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006718.1 /DEF=Homo sapiens pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 2, mRNA. /FEA=mRNA /GEN=PLAGL1 /PROD=pleiomorphic adenoma gene-like 1 isoform 2 /DB_XREF=gi:6031193 /UG=Hs.75825 pleiomorphic adenoma gene-like 1 /FL=gb:NM_006718.1 NM_006718 pleiomorphic adenoma gene-like 1 PLAGL1 5325 NM_001080951 /// NM_001080952 /// NM_001080953 /// NM_001080954 /// NM_001080955 /// NM_001080956 /// NM_001289037 /// NM_001289038 /// NM_001289039 /// NM_001289040 /// NM_001289041 /// NM_001289042 /// NM_001289043 /// NM_001289044 /// NM_001289045 /// NM_001289046 /// NM_001289047 /// NM_001289048 /// NM_001289049 /// NM_002656 /// NM_006718 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207944_at NM_006188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006188.2 /DEF=Homo sapiens oncomodulin (OCM), mRNA. /FEA=mRNA /GEN=OCM /PROD=oncomodulin /DB_XREF=gi:12707573 /UG=Hs.218403 oncomodulin /FL=gb:NM_006188.2 NM_006188 oncomodulin 2 OCM2 4951 NM_006188 0005509 // calcium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207945_s_at NM_001893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001893.1 /DEF=Homo sapiens casein kinase 1, delta (CSNK1D), mRNA. /FEA=mRNA /GEN=CSNK1D /PROD=casein kinase 1, delta /DB_XREF=gi:4503090 /UG=Hs.75852 casein kinase 1, delta /FL=gb:NM_001893.1 gb:U29171.1 NM_001893 casein kinase 1, delta CSNK1D 1453 NM_001893 /// NM_139062 /// NR_110578 /// XM_005256336 /// XM_005256337 /// XR_243518 /// XR_430027 /// XR_430028 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 207946_at NM_005878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005878.1 /DEF=Homo sapiens trinucleotide repeat containing 3 (TNRC3), mRNA. /FEA=mRNA /GEN=TNRC3 /PROD=trinucleotide repeat containing 3 /DB_XREF=gi:5031712 /UG=Hs.21858 trinucleotide repeat containing 3 /FL=gb:U80747.1 gb:NM_005878.1 NM_005878 mastermind-like 3 (Drosophila) MAML3 55534 NM_018717 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay 207949_s_at NM_004968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004968.1 /DEF=Homo sapiens islet cell autoantigen 1 (69kD) (ICA1), transcript variant 2, mRNA. /FEA=mRNA /GEN=ICA1 /PROD=islet cell autoantigen 1, isoform 2 /DB_XREF=gi:4826767 /UG=Hs.167927 islet cell autoantigen 1 (69kD) /FL=gb:U38260.1 gb:NM_004968.1 NM_004968 islet cell autoantigen 1, 69kDa ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 207950_s_at NM_001149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001149.1 /DEF=Homo sapiens ankyrin 3, node of Ranvier (ankyrin G) (ANK3), transcript variant 2, mRNA. /FEA=mRNA /GEN=ANK3 /PROD=ankyrin 3, isoform 2 /DB_XREF=gi:4502092 /UG=Hs.75893 ankyrin 3, node of Ranvier (ankyrin G) /FL=gb:U43965.1 gb:NM_001149.1 NM_001149 ankyrin 3, node of Ranvier (ankyrin G) ANK3 288 NM_001149 /// NM_001204403 /// NM_001204404 /// NM_020987 /// XM_005269715 /// XM_005269716 /// XM_006717782 /// XM_006717783 /// XM_006717784 /// XM_006717785 /// XM_006717786 /// XM_006717787 /// XM_006717788 /// XM_006717789 /// XM_006717790 /// XM_006717791 /// XM_006717792 /// XM_006717793 /// XM_006717794 /// XM_006717795 /// XM_006717796 /// XM_006717797 /// XM_006717798 /// XM_006717799 /// XM_006717800 /// XM_006717801 /// XM_006717802 /// XM_006717803 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010650 // positive regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045838 // positive regulation of membrane potential // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072660 // maintenance of protein location in plasma membrane // inferred from genetic interaction /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 1900827 // positive regulation of membrane depolarization during cardiac muscle cell action potential // inferred from sequence or structural similarity /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0014731 // spectrin-associated cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from sequence or structural similarity /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from sequence or structural similarity 207951_at NM_001891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001891.1 /DEF=Homo sapiens casein, beta (CSN2), mRNA. /FEA=mRNA /GEN=CSN2 /PROD=casein, beta /DB_XREF=gi:4503086 /UG=Hs.2242 casein, beta /FL=gb:NM_001891.1 NM_001891 casein beta CSN2 1447 NM_001891 /// XM_005265647 0006810 // transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007595 // lactation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0004857 // enzyme inhibitor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement 207952_at NM_000879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000879.1 /DEF=Homo sapiens interleukin 5 (colony-stimulating factor, eosinophil) (IL5), mRNA. /FEA=mRNA /GEN=IL5 /PROD=interleukin 5 (colony-stimulating factor,eosinophil) /DB_XREF=gi:4504670 /UG=Hs.2247 interleukin 5 (colony-stimulating factor, eosinophil) /FL=gb:NM_000879.1 NM_000879 interleukin 5 IL5 3567 NM_000879 /// XM_005271988 /// XM_006714601 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0045645 // positive regulation of eosinophil differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051024 // positive regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0071803 // positive regulation of podosome assembly // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005137 // interleukin-5 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 207953_at AF010144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF010144.1 /DEF=Homo sapiens neuronal thread protein AD7c-NTP mRNA, complete cds. /FEA=mRNA /PROD=neuronal thread protein AD7c-NTP /DB_XREF=gi:3002526 /UG=Hs.129735 neuronal thread protein /FL=gb:AF010144.1 gb:NM_014486.1 AF010144 207954_at NM_002050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002050.1 /DEF=Homo sapiens GATA-binding protein 2 (GATA2), mRNA. /FEA=mRNA /GEN=GATA2 /PROD=GATA-binding protein 2 /DB_XREF=gi:4503926 /UG=Hs.760 GATA-binding protein 2 /FL=gb:M77810.1 gb:NM_002050.1 NM_002050 GATA binding protein 2 GATA2 2624 NM_001145661 /// NM_001145662 /// NM_032638 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0021514 // ventral spinal cord interneuron differentiation // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035065 // regulation of histone acetylation // inferred from electronic annotation /// 0035854 // eosinophil fate commitment // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048469 // cell maturation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060872 // semicircular canal development // inferred from electronic annotation /// 0070345 // negative regulation of fat cell proliferation // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 207955_at NM_006664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006664.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 27 (SCYA27), mRNA. /FEA=mRNA /GEN=SCYA27 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 27 /DB_XREF=gi:5730034 /UG=Hs.225948 small inducible cytokine subfamily A (Cys-Cys), member 27 /FL=gb:AF082393.1 gb:NM_006664.1 gb:AB010445.1 NM_006664 chemokine (C-C motif) ligand 27 CCL27 10850 NM_006664 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 207956_x_at NM_015928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015928.1 /DEF=Homo sapiens androgen-induced prostate proliferative shutoff associated protein (AS3), mRNA. /FEA=mRNA /GEN=AS3 /PROD=androgen-induced prostate proliferative shutoffassociated protein /DB_XREF=gi:7705287 /UG=Hs.168625 androgen-induced prostate proliferative shutoff associated protein /FL=gb:U95825.2 gb:NM_015928.1 NM_015928 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) PDS5B 23047 NM_015032 /// NM_015928 /// XM_005266295 /// XM_005266296 /// XM_005266297 /// XM_005266298 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement 207957_s_at NM_002738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002738.1 /DEF=Homo sapiens protein kinase C, beta 1 (PRKCB1), mRNA. /FEA=mRNA /GEN=PRKCB1 /PROD=protein kinase C, beta 1 /DB_XREF=gi:4506068 /UG=Hs.77202 protein kinase C, beta 1 /FL=gb:NM_002738.1 NM_002738 protein kinase C, beta PRKCB 5579 NM_002738 /// NM_212535 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010829 // negative regulation of glucose transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042953 // lipoprotein transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050861 // positive regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay 207958_at NM_006798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006798.1 /DEF=Homo sapiens UDP glycosyltransferase 2 family, polypeptide A1 (UGT2A1), mRNA. /FEA=mRNA /GEN=UGT2A1 /PROD=UDP glycosyltransferase 2 family, polypeptideA1 /DB_XREF=gi:5803212 /UG=Hs.225950 UDP glycosyltransferase 2 family, polypeptide A1 /FL=gb:NM_006798.1 NM_006798 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus /// UDP glucuronosyltransferase 2 family, polypeptide A2 UGT2A1 /// UGT2A2 10941 /// 574537 NM_001105677 /// NM_001252274 /// NM_001252275 /// NM_006798 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // traceable author statement /// 0009593 // detection of chemical stimulus // traceable author statement /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0052695 // cellular glucuronidation // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 207959_s_at NM_004662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004662.1 /DEF=Homo sapiens dynein, axonemal, heavy polypeptide 17-like (DNAH17L), mRNA. /FEA=mRNA /GEN=DNAH17L /PROD=dynein, axonemal, heavy polypeptide 17-like /DB_XREF=gi:4758175 /UG=Hs.169148 dynein, axonemal, heavy polypeptide 17-like /FL=gb:NM_004662.1 NM_004662 dynein, axonemal, heavy chain 9 DNAH9 1770 NM_001372 /// NM_004662 /// XM_006721465 /// XM_006721466 /// XM_006721467 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 207960_at NM_012277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012277.1 /DEF=Homo sapiens pancreatic beta cell growth factor (INGAP), mRNA. /FEA=mRNA /GEN=INGAP /PROD=pancreatic beta cell growth factor /DB_XREF=gi:6912433 /UG=Hs.123060 pancreatic beta cell growth factor /FL=gb:U41737.1 gb:NM_012277.1 NM_012277 207961_x_at NM_022870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022870.1 /DEF=Homo sapiens myosin, heavy polypeptide 11, smooth muscle (MYH11), transcript variant SM3, mRNA. /FEA=mRNA /GEN=MYH11 /PROD=smooth muscle myosin heavy chain 11, isoformSM3 /DB_XREF=gi:13124876 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022870.1 gb:AB020673.1 NM_022870 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0051015 // actin filament binding // inferred from electronic annotation 207962_at NM_007058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007058.1 /DEF=Homo sapiens calpain 11 (CAPN11), mRNA. /FEA=mRNA /GEN=CAPN11 /PROD=calpain 11 /DB_XREF=gi:5901915 /UG=Hs.225953 calpain 11 /FL=gb:NM_007058.1 NM_007058 calpain 11 CAPN11 11131 NM_007058 /// XM_006714984 /// XM_006714985 /// XM_006714986 /// XM_006714987 0006508 // proteolysis // not recorded 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207963_at NM_014354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014354.1 /DEF=Homo sapiens HGC6.1.1 protein (HGC6.1.1), mRNA. /FEA=mRNA /GEN=HGC6.1.1 /PROD=HGC6.1.1 protein /DB_XREF=gi:7657155 /UG=Hs.225962 HGC6.1.1 protein /FL=gb:AB016899.1 gb:NM_014354.1 NM_014354 KIF25 antisense RNA 1 KIF25-AS1 100505879 NM_014354 /// NR_103750 207964_x_at NM_021068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021068.1 /DEF=Homo sapiens interferon, alpha 4 (IFNA4), mRNA. /FEA=mRNA /GEN=IFNA4 /PROD=interferon, alpha 4 /DB_XREF=gi:10835102 /UG=Hs.1510 interferon, alpha 4 /FL=gb:NM_021068.1 gb:M27318.1 NM_021068 interferon, alpha 4 IFNA4 3441 NM_021068 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // not recorded 207965_at NM_020999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020999.1 /DEF=Homo sapiens neurogenin 3 (NEUROG3), mRNA. /FEA=mRNA /GEN=NEUROG3 /PROD=neurogenin 3 /DB_XREF=gi:10337610 /UG=Hs.225996 neurogenin 3 /FL=gb:NM_020999.1 NM_020999 neurogenin 3 NEUROG3 50674 NM_020999 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0021510 // spinal cord development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 207966_s_at NM_012201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012201.1 /DEF=Homo sapiens Golgi apparatus protein 1 (GLG1), mRNA. /FEA=mRNA /GEN=GLG1 /PROD=Golgi apparatus protein 1 /DB_XREF=gi:6912389 /UG=Hs.78979 Golgi apparatus protein 1 /FL=gb:U28811.1 gb:U64791.1 gb:NM_012201.1 NM_012201 golgi glycoprotein 1 GLG1 2734 NM_001145666 /// NM_001145667 /// NM_012201 /// NR_027264 /// NR_027265 0007596 // blood coagulation // traceable author statement /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060349 // bone morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 207967_at NM_007258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007258.1 /DEF=Homo sapiens vacuolar protein sorting 45A (yeast homolog) (VPS45A), mRNA. /FEA=mRNA /GEN=VPS45A /PROD=vacuolar protein sorting 45A (yeast homolog) /DB_XREF=gi:6005945 /UG=Hs.226025 vacuolar protein sorting 45A (yeast homolog) /FL=gb:U35246.1 gb:NM_007258.1 NM_007258 vacuolar protein sorting 45 homolog (S. cerevisiae) VPS45 11311 NM_001279353 /// NM_001279354 /// NM_001279355 /// NM_007259 /// NR_103998 /// XM_006711142 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity 207968_s_at NM_002397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002397.1 /DEF=Homo sapiens MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (MEF2C), mRNA. /FEA=mRNA /GEN=MEF2C /PROD=MADS box transcription enhancer factor 2,polypeptide C (myocyte enhancer factor 2C) /DB_XREF=gi:4505146 /UG=Hs.78995 MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) /FL=gb:NM_002397.1 NM_002397 myocyte enhancer factor 2C MEF2C 4208 NM_001131005 /// NM_001193347 /// NM_001193348 /// NM_001193349 /// NM_001193350 /// NM_002397 /// XM_005248511 /// XM_006714618 /// XM_006714619 /// XM_006714620 /// XM_006714621 /// XM_006714622 /// XM_006714623 /// XM_006714624 /// XM_006714625 0000002 // mitochondrial genome maintenance // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0003138 // primary heart field specification // inferred from sequence or structural similarity /// 0003139 // secondary heart field specification // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003185 // sinoatrial valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from expression pattern /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007507 // heart development // non-traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from expression pattern /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030318 // melanocyte differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042692 // muscle cell differentiation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0045663 // positive regulation of myoblast differentiation // inferred from mutant phenotype /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046928 // regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048311 // mitochondrion distribution // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from mutant phenotype /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0055005 // ventricular cardiac myofibril assembly // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090073 // positive regulation of protein homodimerization activity // inferred from sequence or structural similarity /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from direct assay /// 2000987 // positive regulation of behavioral fear response // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from direct assay 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003680 // AT DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 207969_x_at NM_020109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020109.1 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 5, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform eprecursor /DB_XREF=gi:9955932 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:NM_020109.1 NM_020109 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 207971_s_at NM_015147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015147.1 /DEF=Homo sapiens KIAA0582 protein (KIAA0582), mRNA. /FEA=mRNA /GEN=KIAA0582 /PROD=KIAA0582 protein /DB_XREF=gi:13124755 /UG=Hs.79507 KIAA0582 protein /FL=gb:BC002982.1 gb:NM_015147.1 gb:BC004873.1 NM_015147 centrosomal protein 68kDa CEP68 23177 NM_015147 /// XM_005264218 /// XM_005264219 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 207972_at NM_000171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000171.1 /DEF=Homo sapiens glycine receptor, alpha 1 (startle diseasehyperekplexia, stiff man syndrome) (GLRA1), mRNA. /FEA=mRNA /GEN=GLRA1 /PROD=glycine receptor, alpha 1 /DB_XREF=gi:4504018 /UG=Hs.121490 glycine receptor, alpha 1 (startle diseasehyperekplexia, stiff man syndrome) /FL=gb:NM_000171.1 NM_000171 glycine receptor, alpha 1 GLRA1 2741 NM_000171 /// NM_001146040 /// NM_001292000 /// XM_005268411 /// XM_005268412 0001508 // action potential // inferred from electronic annotation /// 0001964 // startle response // inferred from mutant phenotype /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from direct assay /// 0006820 // anion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0060012 // synaptic transmission, glycinergic // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from genetic interaction /// 1902476 // chloride transmembrane transport // inferred from mutant phenotype /// 2000344 // positive regulation of acrosome reaction // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016594 // glycine binding // inferred from direct assay /// 0016933 // extracellular-glycine-gated ion channel activity // inferred from electronic annotation /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from direct assay /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from genetic interaction /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from mutant phenotype /// 0022824 // transmitter-gated ion channel activity // inferred from electronic annotation /// 0030977 // taurine binding // inferred from direct assay 207973_x_at NM_020110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020110.1 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 10, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform jprecursor /DB_XREF=gi:9955934 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:NM_020110.1 NM_020110 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 207974_s_at NM_006930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006930.1 /DEF=Homo sapiens S-phase kinase-associated protein 1A (p19A) (SKP1A), mRNA. /FEA=mRNA /GEN=SKP1A /PROD=S-phase kinase-associated protein 1A (p19A) /DB_XREF=gi:5902087 /UG=Hs.227950 S-phase kinase-associated protein 1A (p19A) /FL=gb:NM_006930.1 gb:U33760.1 NM_006930 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 207976_at NM_025010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025010.1 /DEF=Homo sapiens KIAA0795 protein (KIAA0795), mRNA. /FEA=mRNA /GEN=KIAA0795 /PROD=hypothetical protein FLJ13703 /DB_XREF=gi:13430877 /UG=Hs.22926 KIAA0795 protein /FL=gb:NM_025010.1 NM_025010 kelch-like family member 18 KLHL18 23276 NM_025010 /// XM_005265001 /// XM_005265002 /// XM_005265003 /// XM_006713079 207977_s_at NM_001937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001937.2 /DEF=Homo sapiens dermatopontin (DPT), mRNA. /FEA=mRNA /GEN=DPT /PROD=dermatopontin precursor /DB_XREF=gi:4755134 /UG=Hs.80552 dermatopontin /FL=gb:Z22865.1 gb:NM_001937.2 NM_001937 dermatopontin DPT 1805 NM_001937 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 207978_s_at NM_006981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006981.1 /DEF=Homo sapiens nuclear receptor subfamily 4, group A, member 3 (NR4A3), mRNA. /FEA=mRNA /GEN=NR4A3 /PROD=nuclear receptor subfamily 4, group A, member 3 /DB_XREF=gi:11276070 /UG=Hs.80561 nuclear receptor subfamily 4, group A, member 3 /FL=gb:NM_006981.1 gb:D78579.1 NM_006981 nuclear receptor subfamily 4, group A, member 3 NR4A3 8013 NM_006981 /// NM_173198 /// NM_173199 /// NM_173200 /// XM_005252237 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060005 // vestibular reflex // inferred from electronic annotation /// 2000108 // positive regulation of leukocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207979_s_at NM_004931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004931.1 /DEF=Homo sapiens CD8 antigen, beta polypeptide 1 (p37) (CD8B1), mRNA. /FEA=mRNA /GEN=CD8B1 /PROD=CD8 antigen, beta polypeptide 1 (p37) /DB_XREF=gi:4826666 /UG=Hs.2299 CD8 antigen, beta polypeptide 1 (p37) /FL=gb:NM_004931.1 NM_004931 CD8b molecule /// putative T-cell surface glycoprotein CD8 beta-2 chain-like CD8B /// LOC100996919 926 /// 100996919 NM_001178100 /// NM_004931 /// NM_172099 /// NM_172101 /// NM_172102 /// NM_172213 /// XM_003846653 /// XR_244970 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0042101 // T cell receptor complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement /// 0042288 // MHC class I protein binding // non-traceable author statement 207980_s_at NM_006079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006079.1 /DEF=Homo sapiens Cbpp300-interacting transactivator, with GluAsp-rich carboxy-terminal domain, 2 (CITED2), mRNA. /FEA=mRNA /GEN=CITED2 /PROD=Cbpp300-interacting transactivator, withGluAsp-rich carboxy-terminal domain, 2 /DB_XREF=gi:5174416 /UG=Hs.82071 Cbpp300-interacting transactivator, with GluAsp-rich carboxy-terminal domain, 2 /FL=gb:U65093.1 gb:NM_006079.1 NM_006079 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 CITED2 10370 NM_001168388 /// NM_001168389 /// NM_006079 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007530 // sex determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021602 // cranial nerve morphogenesis // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from mutant phenotype /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046697 // decidualization // inferred from electronic annotation /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060971 // embryonic heart tube left/right pattern formation // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from electronic annotation /// 0061308 // cardiac neural crest cell development involved in heart development // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900164 // nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0050693 // LBD domain binding // inferred from physical interaction 207981_s_at NM_001438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001438.1 /DEF=Homo sapiens estrogen-related receptor gamma (ESRRG), mRNA. /FEA=mRNA /GEN=ESRRG /PROD=estrogen-related receptor gamma /DB_XREF=gi:4503604 /UG=Hs.151017 estrogen-related receptor gamma /FL=gb:AF058291.1 gb:NM_001438.1 NM_001438 estrogen-related receptor gamma ESRRG 2104 NM_001134285 /// NM_001243505 /// NM_001243506 /// NM_001243507 /// NM_001243509 /// NM_001243510 /// NM_001243511 /// NM_001243512 /// NM_001243513 /// NM_001243514 /// NM_001243515 /// NM_001243518 /// NM_001243519 /// NM_001438 /// NM_206594 /// NM_206595 /// XM_006711203 /// XM_006711204 /// XM_006711205 /// XM_006711206 /// XM_006711207 /// XM_006711208 /// XM_006711209 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050682 // AF-2 domain binding // inferred from sequence or structural similarity 207982_at NM_005323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005323.2 /DEF=Homo sapiens H1 histone family, member T (testis-specific) (H1FT), mRNA. /FEA=mRNA /GEN=H1FT /PROD=H1 histone family, member T (testis-specific) /DB_XREF=gi:5579459 /UG=Hs.123064 H1 histone family, member T (testis-specific) /FL=gb:NM_005323.2 NM_005323 histone cluster 1, H1t HIST1H1T 3010 NM_005323 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 207983_s_at NM_006603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006603.1 /DEF=Homo sapiens stromal antigen 2 (STAG2), mRNA. /FEA=mRNA /GEN=STAG2 /PROD=stromal antigen 2 /DB_XREF=gi:5730068 /UG=Hs.8217 stromal antigen 2 /FL=gb:NM_006603.1 NM_006603 stromal antigen 2 STAG2 10735 NM_001042749 /// NM_001042750 /// NM_001042751 /// NM_001282418 /// NM_006603 /// XM_005262357 /// XM_005262358 /// XM_005262359 /// XM_005262360 /// XM_005262361 /// XM_006724727 /// XM_006724728 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 207984_s_at NM_005374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005374.1 /DEF=Homo sapiens membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (MPP2), mRNA. /FEA=mRNA /GEN=MPP2 /PROD=palmitoylated membrane protein 2 /DB_XREF=gi:4885492 /UG=Hs.23205 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) /FL=gb:NM_005374.1 NM_005374 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) MPP2 4355 NM_001278370 /// NM_001278371 /// NM_001278372 /// NM_001278373 /// NM_001278374 /// NM_001278375 /// NM_001278376 /// NM_001278381 /// NM_005374 /// XM_006721912 /// XM_006721913 /// XM_006721914 0007165 // signal transduction // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 207985_at NM_014355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014355.1 /DEF=Homo sapiens enolase alpha, lung-specific (ENO1B), mRNA. /FEA=mRNA /GEN=ENO1B /PROD=enolase alpha, lung-specific /DB_XREF=gi:7657061 /UG=Hs.234748 enolase alpha, lung-specific /FL=gb:NM_014355.1 NM_014355 207986_x_at NM_001915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001915.1 /DEF=Homo sapiens cytochrome b-561 (CYB561), mRNA. /FEA=mRNA /GEN=CYB561 /PROD=cytochrome b-561 /DB_XREF=gi:11993936 /UG=Hs.153028 cytochrome b-561 /FL=gb:NM_001915.1 NM_001915 cytochrome b561 CYB561 1534 NM_001017916 /// NM_001017917 /// NM_001017918 /// NM_001915 /// XM_005257090 /// XM_005257091 /// XM_005257092 /// XM_006721727 0022900 // electron transport chain // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000293 // ferric-chelate reductase activity // inferred from sequence or structural similarity /// 0022865 // transmembrane electron transfer carrier // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207987_s_at NM_000825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000825.1 /DEF=Homo sapiens gonadotropin-releasing hormone 1 (leutinizing-releasing hormone) (GNRH1), mRNA. /FEA=mRNA /GEN=GNRH1 /PROD=gonadotropin-releasing hormone 1(leutinizing-releasing hormone) /DB_XREF=gi:4504054 /UG=Hs.82963 gonadotropin-releasing hormone 1 (leutinizing-releasing hormone) /FL=gb:M12578.1 gb:NM_000825.1 NM_000825 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) GNRH1 2796 NM_000825 /// NM_001083111 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 2000354 // regulation of ovarian follicle development // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005183 // gonadotropin hormone-releasing hormone activity // inferred from electronic annotation 207988_s_at NM_005731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005731.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 2 (34 kD) (ARPC2), mRNA. /FEA=mRNA /GEN=ARPC2 /PROD=actin related protein 23 complex, subunit 2 (34kD) /DB_XREF=gi:5031598 /UG=Hs.83583 actin related protein 23 complex, subunit 2 (34 kD) /FL=gb:AF006085.1 gb:NM_005731.1 NM_005731 actin related protein 2/3 complex, subunit 2, 34kDa ARPC2 10109 NM_005731 /// NM_152862 /// XM_006712173 0006928 // cellular component movement // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from electronic annotation /// 0035650 // AP-1 adaptor complex binding // inferred from electronic annotation /// 0071933 // Arp2/3 complex binding // inferred from electronic annotation 207989_at NM_000914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000914.1 /DEF=Homo sapiens opioid receptor, mu 1 (OPRM1), mRNA. /FEA=mRNA /GEN=OPRM1 /PROD=opioid receptor, mu 1 /DB_XREF=gi:4505514 /UG=Hs.2353 opioid receptor, mu 1 /FL=gb:NM_000914.1 gb:L25119.1 gb:L29301.1 NM_000914 opioid receptor, mu 1 OPRM1 4988 NM_000914 /// NM_001008503 /// NM_001008504 /// NM_001008505 /// NM_001145279 /// NM_001145280 /// NM_001145281 /// NM_001145282 /// NM_001145283 /// NM_001145284 /// NM_001145285 /// NM_001145286 /// NM_001145287 /// NM_001285522 /// NM_001285523 /// NM_001285524 /// NM_001285526 /// NM_001285527 /// NM_001285528 /// NR_104348 /// NR_104349 /// NR_104350 /// NR_104351 /// XM_006715496 /// XM_006715497 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from mutant phenotype /// 0007600 // sensory perception // non-traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0033554 // cellular response to stress // inferred from mutant phenotype /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0048149 // behavioral response to ethanol // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from mutant phenotype /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0061358 // negative regulation of Wnt protein secretion // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0071315 // cellular response to morphine // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0004979 // beta-endorphin receptor activity // inferred from mutant phenotype /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0038047 // morphine receptor activity // inferred from sequence or structural similarity 207990_x_at NM_020114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020114.1 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 9, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform iprecursor /DB_XREF=gi:9955942 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:NM_020114.1 NM_020114 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 207991_x_at NM_020113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020113.1 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 8, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform hprecursor /DB_XREF=gi:9955940 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:NM_020113.1 NM_020113 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 207992_s_at NM_000480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000480.1 /DEF=Homo sapiens adenosine monophosphate deaminase (isoform E) (AMPD3), mRNA. /FEA=mRNA /GEN=AMPD3 /PROD=adenosine monophosphate deaminase (isoform E) /DB_XREF=gi:4502078 /UG=Hs.83918 adenosine monophosphate deaminase (isoform E) /FL=gb:NM_000480.1 NM_000480 adenosine monophosphate deaminase 3 AMPD3 272 NM_000480 /// NM_001025389 /// NM_001025390 /// NM_001172430 /// NM_001172431 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006188 // IMP biosynthetic process // inferred from electronic annotation /// 0006196 // AMP catabolic process // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0032264 // IMP salvage // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003876 // AMP deaminase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 207993_s_at NM_007236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007236.1 /DEF=Homo sapiens calcium binding protein P22 (CHP), mRNA. /FEA=mRNA /GEN=CHP /PROD=calcium binding protein P22 /DB_XREF=gi:6005730 /UG=Hs.85301 calcium binding protein P22 /FL=gb:U61538.1 gb:NM_007236.1 NM_007236 calcineurin-like EF-hand protein 1 CHP1 11261 NM_007236 /// XM_005254140 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0022406 // membrane docking // inferred from sequence or structural similarity /// 0031122 // cytoplasmic microtubule organization // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0031953 // negative regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from sequence or structural similarity /// 0042308 // negative regulation of protein import into nucleus // inferred from direct assay /// 0045056 // transcytosis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051222 // positive regulation of protein transport // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from direct assay /// 0060050 // positive regulation of protein glycosylation // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from sequence or structural similarity /// 0061025 // membrane fusion // inferred from sequence or structural similarity /// 0070885 // negative regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from sequence or structural similarity /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // traceable author statement /// 0019900 // kinase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay 207994_s_at L29301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L29301.1 /DEF=Homo sapiens opioid receptor mRNA, complete cds. /FEA=mRNA /PROD=opioid receptor /DB_XREF=gi:459831 /UG=Hs.2353 opioid receptor, mu 1 /FL=gb:NM_000914.1 gb:L25119.1 gb:L29301.1 L29301 opioid receptor, mu 1 OPRM1 4988 NM_000914 /// NM_001008503 /// NM_001008504 /// NM_001008505 /// NM_001145279 /// NM_001145280 /// NM_001145281 /// NM_001145282 /// NM_001145283 /// NM_001145284 /// NM_001145285 /// NM_001145286 /// NM_001145287 /// NM_001285522 /// NM_001285523 /// NM_001285524 /// NM_001285526 /// NM_001285527 /// NM_001285528 /// NR_104348 /// NR_104349 /// NR_104350 /// NR_104351 /// XM_006715496 /// XM_006715497 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from mutant phenotype /// 0007600 // sensory perception // non-traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0033554 // cellular response to stress // inferred from mutant phenotype /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0048149 // behavioral response to ethanol // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from mutant phenotype /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0061358 // negative regulation of Wnt protein secretion // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0071315 // cellular response to morphine // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0004979 // beta-endorphin receptor activity // inferred from mutant phenotype /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0038047 // morphine receptor activity // inferred from sequence or structural similarity 207995_s_at NM_014257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014257.1 /DEF=Homo sapiens CD209 antigen-like (CD209L), mRNA. /FEA=mRNA /GEN=CD209L /PROD=CD209 antigen-like /DB_XREF=gi:7657173 /UG=Hs.23759 CD209 antigen-like /FL=gb:AB015629.1 gb:NM_014257.1 NM_014257 C-type lectin domain family 4, member M CLEC4M 10332 NM_001144904 /// NM_001144905 /// NM_001144906 /// NM_001144907 /// NM_001144908 /// NM_001144909 /// NM_001144910 /// NM_001144911 /// NM_014257 /// NM_214675 /// NM_214676 /// NR_026707 /// NR_026708 /// NR_026709 /// XM_006722611 /// XM_006722612 /// XM_006722613 /// XM_006722614 /// XM_006722615 /// XR_430125 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0009988 // cell-cell recognition // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019062 // virion attachment to host cell // traceable author statement /// 0019079 // viral genome replication // non-traceable author statement /// 0019882 // antigen processing and presentation // non-traceable author statement /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0046968 // peptide antigen transport // non-traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005537 // mannose binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0030369 // ICAM-3 receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046790 // virion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 207996_s_at NM_004338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004338.1 /DEF=Homo sapiens chromosome 18 open reading frame 1 (C18ORF1), mRNA. /FEA=mRNA /GEN=C18ORF1 /PROD=chromosome 18 open reading frame 1 /DB_XREF=gi:4757883 /UG=Hs.153498 chromosome 18 open reading frame 1 /FL=gb:AF009426.1 gb:NM_004338.1 NM_004338 low density lipoprotein receptor class A domain containing 4 LDLRAD4 753 NM_001003674 /// NM_001003675 /// NM_001276249 /// NM_001276251 /// NM_004338 /// NM_181481 /// NM_181482 /// NM_181483 /// XM_005258140 /// XM_006722350 /// XM_006722351 /// XM_006722352 /// XM_006722353 /// XM_006722354 /// XM_006722355 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 207998_s_at NM_000720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000720.1 /DEF=Homo sapiens calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), mRNA. /FEA=mRNA /GEN=CACNA1D /PROD=calcium channel, voltage-dependent, L type,alpha 1D subunit /DB_XREF=gi:4502526 /UG=Hs.23838 calcium channel, voltage-dependent, L type, alpha 1D subunit /FL=gb:M83566.1 gb:NM_000720.1 NM_000720 calcium channel, voltage-dependent, L type, alpha 1D subunit CACNA1D 776 NM_000720 /// NM_001128839 /// NM_001128840 /// XM_005265448 /// XM_006713325 0006066 // alcohol metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019285 // glycine betaine biosynthetic process from choline // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0086010 // membrane depolarization during action potential // not recorded /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred by curator /// 0086046 // membrane depolarization during SA node cell action potential // inferred from electronic annotation /// 0086052 // membrane repolarization during SA node cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901379 // regulation of potassium ion transmembrane transport // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay /// 0008812 // choline dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from physical interaction /// 0086007 // voltage-gated calcium channel activity involved in cardiac muscle cell action potential // inferred by curator /// 0086059 // voltage-gated calcium channel activity involved SA node cell action potential // inferred from mutant phenotype 207999_s_at NM_001112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001112.1 /DEF=Homo sapiens adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) (ADARB1), transcript variant DRADA2a, mRNA. /FEA=mRNA /GEN=ADARB1 /PROD=RNA-specific adenosine deaminase B1, isoformDRADA2a /DB_XREF=gi:4501918 /UG=Hs.85302 adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) /FL=gb:U82120.1 gb:U76420.1 gb:NM_001112.1 NM_001112 adenosine deaminase, RNA-specific, B1 ADARB1 104 NM_001033049 /// NM_001112 /// NM_001160230 /// NM_015833 /// NM_015834 /// NR_027672 /// NR_027673 /// NR_027674 /// NR_073200 /// XM_006723953 /// XM_006723954 /// XM_006723955 /// XM_006723956 /// XM_006723957 /// XM_006723958 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred by curator /// 0016556 // mRNA modification // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208000_at NM_002066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002066.1 /DEF=Homo sapiens GPI anchored molecule like protein (GML), mRNA. /FEA=mRNA /GEN=GML /PROD=GPI anchored molecule like protein /DB_XREF=gi:4504032 /UG=Hs.86161 GPI anchored molecule like protein /FL=gb:D84290.1 gb:NM_002066.1 NM_002066 glycosylphosphatidylinositol anchored molecule like GML 2765 NM_002066 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 208002_s_at NM_007274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007274.1 /DEF=Homo sapiens cytosolic acyl coenzyme A thioester hydrolase (HBACH), mRNA. /FEA=mRNA /GEN=HBACH /PROD=cytosolic acyl coenzyme A thioester hydrolase /DB_XREF=gi:6857796 /UG=Hs.8679 cytosolic acyl coenzyme A thioester hydrolase /FL=gb:U91316.1 gb:NM_007274.1 NM_007274 acyl-CoA thioesterase 7 ACOT7 11332 NM_007274 /// NM_181862 /// NM_181863 /// NM_181864 /// NM_181865 /// NM_181866 /// XM_005263427 0006629 // lipid metabolic process // traceable author statement /// 0009062 // fatty acid catabolic process // inferred from electronic annotation /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0036114 // medium-chain fatty-acyl-CoA catabolic process // inferred from direct assay /// 0036116 // long-chain fatty-acyl-CoA catabolic process // inferred from direct assay /// 0051792 // medium-chain fatty acid biosynthetic process // inferred from direct assay /// 1900535 // palmitic acid biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047617 // acyl-CoA hydrolase activity // inferred from electronic annotation 208003_s_at NM_006599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006599.1 /DEF=Homo sapiens nuclear factor of activated T-cells 5, tonicity-resonsive (NFAT5), mRNA. /FEA=mRNA /GEN=NFAT5 /PROD=nuclear factor of activated T-cells 5,tonicity-resonsive /DB_XREF=gi:5729944 /UG=Hs.86998 nuclear factor of activated T-cells 5, tonicity-responsive /FL=gb:AB020634.1 gb:AF163836.1 gb:NM_006599.1 NM_006599 nuclear factor of activated T-cells 5, tonicity-responsive NFAT5 10725 NM_001113178 /// NM_006599 /// NM_138713 /// NM_138714 /// NM_173214 /// NM_173215 /// XM_005255777 /// XM_006721125 0001816 // cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007588 // excretion // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0070884 // regulation of calcineurin-NFAT signaling cascade // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208004_at NM_021225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021225.1 /DEF=Homo sapiens basic proline-rich protein (BPLP), mRNA. /FEA=mRNA /GEN=BPLP /PROD=basic proline-rich protein /DB_XREF=gi:10864034 /UG=Hs.87198 basic proline-rich protein /FL=gb:NM_021225.1 NM_021225 proline rich, lacrimal 1 PROL1 58503 NM_021225 0001895 // retina homeostasis // inferred from expression pattern /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from direct assay 208005_at NM_004822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004822.1 /DEF=Homo sapiens netrin 1 (NTN1), mRNA. /FEA=mRNA /GEN=NTN1 /PROD=netrin 1 /DB_XREF=gi:4758839 /UG=Hs.241380 netrin 1 /FL=gb:U75586.1 gb:NM_004822.1 NM_004822 netrin 1 NTN1 9423 NM_004822 /// XM_006721595 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033564 // anterior/posterior axon guidance // inferred from electronic annotation /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208006_at NM_012188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012188.2 /DEF=Homo sapiens forkhead box I1 (FOXI1), mRNA. /FEA=mRNA /GEN=FOXI1 /PROD=forkhead box I1 /DB_XREF=gi:11990619 /UG=Hs.87236 forkhead box I1 /FL=gb:NM_012188.2 gb:L13203.1 NM_012188 forkhead box I1 FOXI1 2299 NM_012188 /// NM_144769 /// XM_005265846 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0008301 // DNA binding, bending // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 208007_at NM_012122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012122.1 /DEF=Homo sapiens carboxylesterase 3 (brain) (CES3), mRNA. /FEA=mRNA /GEN=CES3 /PROD=carboxylesterase 3 /DB_XREF=gi:6912297 /UG=Hs.241388 carboxylesterase 3 (brain) /FL=gb:AB025028.1 gb:NM_012122.1 NM_012122 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // traceable author statement /// 0009636 // response to toxic substance // traceable author statement /// 0016042 // lipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // non-traceable author statement /// 0019626 // short-chain fatty acid catabolic process // inferred from direct assay /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0046464 // acylglycerol catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0004771 // sterol esterase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030339 // fatty-acyl-ethyl-ester synthase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // /// 0052689 // carboxylic ester hydrolase activity // inferred from direct assay /// 0052689 // carboxylic ester hydrolase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // inferred from mutant phenotype /// 0052689 // carboxylic ester hydrolase activity // traceable author statement 208008_at NM_015594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015594.1 /DEF=Homo sapiens DKFZP434O047 protein (DKFZP434O047), mRNA. /FEA=mRNA /GEN=DKFZP434O047 /PROD=DKFZP434O047 protein /DB_XREF=gi:7661585 /UG=Hs.241421 DKFZP434O047 protein /FL=gb:NM_015594.1 NM_015594 TBC1 domain family, member 29 TBC1D29 26083 NM_015594 /// XM_006721805 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 208009_s_at NM_014448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014448.1 /DEF=Homo sapiens putative neuroblastoma protein (NBR), mRNA. /FEA=mRNA /GEN=NBR /PROD=putative neuroblastoma protein /DB_XREF=gi:7657364 /UG=Hs.87435 Rho guanine exchange factor (GEF) 16 /FL=gb:D89016.1 gb:NM_014448.1 NM_014448 Rho guanine nucleotide exchange factor (GEF) 16 ARHGEF16 27237 NM_014448 /// XM_005244740 /// XM_006710578 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0032864 // activation of Cdc42 GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 208010_s_at NM_012411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012411.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), mRNA. /FEA=mRNA /GEN=PTPN22 /PROD=protein tyrosine phosphatase, non-receptor type22 (lymphoid) /DB_XREF=gi:6912613 /UG=Hs.87860 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) /FL=gb:AF001847.1 gb:NM_012411.1 NM_012411 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) PTPN22 26191 NM_001193431 /// NM_012411 /// NM_015967 /// XM_005270738 0002376 // immune system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0032817 // regulation of natural killer cell proliferation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035644 // phosphoanandamide dephosphorylation // inferred from sequence or structural similarity /// 0045088 // regulation of innate immune response // inferred by curator /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0019900 // kinase binding // inferred from sequence or structural similarity 208011_at NM_012411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012411.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), mRNA. /FEA=mRNA /GEN=PTPN22 /PROD=protein tyrosine phosphatase, non-receptor type22 (lymphoid) /DB_XREF=gi:6912613 /UG=Hs.87860 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) /FL=gb:AF001847.1 gb:NM_012411.1 NM_012411 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) PTPN22 26191 NM_001193431 /// NM_012411 /// NM_015967 /// XM_005270738 0002376 // immune system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0032817 // regulation of natural killer cell proliferation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035644 // phosphoanandamide dephosphorylation // inferred from sequence or structural similarity /// 0045088 // regulation of innate immune response // inferred by curator /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0019900 // kinase binding // inferred from sequence or structural similarity 208012_x_at NM_004509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004509.1 /DEF=Homo sapiens interferon-induced protein 41, 30kD (IFI41), mRNA. /FEA=mRNA /GEN=IFI41 /PROD=interferon-induced protein 41, 30kD /DB_XREF=gi:4758585 /UG=Hs.241510 interferon-induced protein 41, 30kD /FL=gb:L22342.1 gb:NM_004509.1 NM_004509 SP110 nuclear body protein SP110 3431 NM_001185015 /// NM_004509 /// NM_004510 /// NM_080424 /// XM_005246525 /// XM_005246527 /// XM_006712486 /// XM_006712487 /// XM_006712488 /// XM_006712489 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208013_s_at NM_020115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020115.1 /DEF=Homo sapiens acrosomal vesicle protein 1 (ACRV1), transcript variant 11, mRNA. /FEA=mRNA /GEN=ACRV1 /PROD=acrosomal vesicle protein 1, isoform kprecursor /DB_XREF=gi:9955944 /UG=Hs.169222 acrosomal vesicle protein 1 /FL=gb:NM_020115.1 NM_020115 acrosomal vesicle protein 1 ACRV1 56 NM_001612 /// NM_020069 /// NM_020107 /// NM_020108 /// NM_020109 /// NM_020110 /// NM_020111 /// NM_020112 /// NM_020113 /// NM_020114 /// NM_020115 /// XM_005271610 0007275 // multicellular organismal development // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 208014_x_at NM_014486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014486.1 /DEF=Homo sapiens neuronal thread protein (AD7C-NTP), mRNA. /FEA=mRNA /GEN=AD7C-NTP /PROD=neuronal thread protein /DB_XREF=gi:7656858 /UG=Hs.129735 neuronal thread protein /FL=gb:AF010144.1 gb:NM_014486.1 NM_014486 208015_at NM_015583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015583.1 /DEF=Homo sapiens DKFZP586M0622 protein (DKFZP586M0622), mRNA. /FEA=mRNA /GEN=DKFZP586M0622 /PROD=DKFZP586M0622 protein /DB_XREF=gi:7661687 /UG=Hs.241544 DKFZP586M0622 protein /FL=gb:NM_015583.1 NM_015583 Homo sapiens cDNA clone IMAGE:7262571, with apparent retained intron. /// SMAD family member 1 BC069804 /// SMAD1 4086 NM_001003688 /// NM_005900 /// XM_005262991 /// XM_005262992 /// XM_005262993 /// XM_006714217 0000165 // MAPK cascade // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001710 // mesodermal cell fate commitment // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042592 // homeostatic process // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction 208016_s_at NM_004835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004835.1 /DEF=Homo sapiens angiotensin receptor 1B (AGTR1B), mRNA. /FEA=mRNA /GEN=AGTR1B /PROD=angiotensin receptor 1B /DB_XREF=gi:4757729 /UG=Hs.89472 angiotensin receptor 1 /FL=gb:D13814.1 gb:NM_004835.1 NM_004835 angiotensin II receptor, type 1 AGTR1 185 NM_000685 /// NM_004835 /// NM_009585 /// NM_031850 /// NM_032049 0001558 // regulation of cell growth // non-traceable author statement /// 0001822 // kidney development // inferred from mutant phenotype /// 0002018 // renin-angiotensin regulation of aldosterone production // non-traceable author statement /// 0002034 // regulation of blood vessel size by renin-angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010873 // positive regulation of cholesterol esterification // inferred from mutant phenotype /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0019229 // regulation of vasoconstriction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032430 // positive regulation of phospholipase A2 activity // inferred from mutant phenotype /// 0033864 // positive regulation of NAD(P)H oxidase activity // traceable author statement /// 0034374 // low-density lipoprotein particle remodeling // non-traceable author statement /// 0035813 // regulation of renal sodium excretion // non-traceable author statement /// 0038166 // angiotensin-activated signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042312 // regulation of vasodilation // inferred by curator /// 0050727 // regulation of inflammatory response // inferred by curator /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from physical interaction /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001596 // angiotensin type I receptor activity // inferred from direct assay /// 0001596 // angiotensin type I receptor activity // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010698 // acetyltransferase activator activity // inferred from mutant phenotype /// 0031711 // bradykinin receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 208017_s_at NM_005369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005369.1 /DEF=Homo sapiens MCF.2 cell line derived transforming sequence (MCF2), mRNA. /FEA=mRNA /GEN=MCF2 /PROD=MCF.2 cell line derived transforming sequence /DB_XREF=gi:4885478 /UG=Hs.89543 MCF.2 cell line derived transforming sequence /FL=gb:J03639.1 gb:NM_005369.1 NM_005369 MCF.2 cell line derived transforming sequence MCF2 4168 NM_001099855 /// NM_001171876 /// NM_001171877 /// NM_001171878 /// NM_001171879 /// NM_005369 /// XM_005262413 /// XM_005262414 /// XM_006724757 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 208018_s_at NM_002110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002110.1 /DEF=Homo sapiens hemopoietic cell kinase (HCK), mRNA. /FEA=mRNA /GEN=HCK /PROD=hemopoietic cell kinase /DB_XREF=gi:4504356 /UG=Hs.89555 hemopoietic cell kinase /FL=gb:M16591.1 gb:NM_002110.1 NM_002110 HCK proto-oncogene, Src family tyrosine kinase HCK 3055 NM_001172129 /// NM_001172130 /// NM_001172131 /// NM_001172132 /// NM_001172133 /// NM_002110 0002376 // immune system process // inferred from electronic annotation /// 0002522 // leukocyte migration involved in immune response // traceable author statement /// 0002758 // innate immune response-activating signal transduction // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043299 // leukocyte degranulation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045728 // respiratory burst after phagocytosis // traceable author statement /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0050764 // regulation of phagocytosis // inferred from mutant phenotype /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071801 // regulation of podosome assembly // inferred from direct assay /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from mutant phenotype /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208019_at NM_003446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003446.1 /DEF=Homo sapiens zinc finger protein 157 (HZF22) (ZNF157), mRNA. /FEA=mRNA /GEN=ZNF157 /PROD=zinc finger protein 157 (HZF22) /DB_XREF=gi:4507998 /UG=Hs.89897 zinc finger protein 157 (HZF22) /FL=gb:NM_003446.1 gb:U28687.1 NM_003446 zinc finger protein 157 ZNF157 7712 NM_003446 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 208020_s_at NM_000719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000719.1 /DEF=Homo sapiens calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C), mRNA. /FEA=mRNA /GEN=CACNA1C /PROD=calcium channel, voltage-dependent, L type,alpha 1C subunit /DB_XREF=gi:4502524 /UG=Hs.89925 calcium channel, voltage-dependent, L type, alpha 1C subunit /FL=gb:NM_000719.1 NM_000719 calcium channel, voltage-dependent, L type, alpha 1C subunit CACNA1C 775 NM_000719 /// NM_001129827 /// NM_001129829 /// NM_001129830 /// NM_001129831 /// NM_001129832 /// NM_001129833 /// NM_001129834 /// NM_001129835 /// NM_001129836 /// NM_001129837 /// NM_001129838 /// NM_001129839 /// NM_001129840 /// NM_001129841 /// NM_001129842 /// NM_001129843 /// NM_001129844 /// NM_001129846 /// NM_001167623 /// NM_001167624 /// NM_001167625 /// NM_199460 /// XM_006719015 /// XM_006719016 /// XM_006719017 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035585 // calcium-mediated signaling using extracellular calcium source // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046620 // regulation of organ growth // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // traceable author statement /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement 0002095 // caveolar macromolecular signaling complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0008331 // high voltage-gated calcium channel activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from physical interaction 208021_s_at NM_002913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002913.1 /DEF=Homo sapiens replication factor C (activator 1) 1 (145kD) (RFC1), mRNA. /FEA=mRNA /GEN=RFC1 /PROD=replication factor C (activator 1) 1 (145kD) /DB_XREF=gi:4506484 /FL=gb:NM_002913.1 NM_002913 replication factor C (activator 1) 1, 145kDa RFC1 5981 NM_001204747 /// NM_002913 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // not recorded /// 0003689 // DNA clamp loader activity // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208022_s_at NM_003671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003671.1 /DEF=Homo sapiens CDC14 (cell division cycle 14, S. cerevisiae) homolog B (CDC14B), mRNA. /FEA=mRNA /GEN=CDC14B /PROD=S. cerevisiae CDC14 homolog, gene B /DB_XREF=gi:4502698 /FL=gb:NM_003671.1 NM_003671 cell division cycle 14B CDC14B 8555 NM_001077181 /// NM_003671 /// NM_033331 /// NM_033332 /// XM_005252286 /// XM_005252287 /// XM_005252288 /// XR_242602 /// XR_242603 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 208023_at NM_003327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003327.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), mRNA. /FEA=mRNA /GEN=TNFRSF4 /PROD=tax-transcriptionally activated glycoprotein 1receptor (homolog of rat OX40ACT35 antigen) /DB_XREF=gi:4507578 /UG=Hs.129780 tumor necrosis factor receptor superfamily, member 4 /FL=gb:NM_003327.1 NM_003327 tumor necrosis factor receptor superfamily, member 4 TNFRSF4 7293 NM_003327 /// XM_005244794 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005031 // tumor necrosis factor-activated receptor activity // inferred from electronic annotation 208024_s_at NM_005675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005675.1 /DEF=Homo sapiens DiGeorge syndrome critical region gene 6 (DGCR6), mRNA. /FEA=mRNA /GEN=DGCR6 /PROD=DiGeorge syndrome critical region protein 6 /DB_XREF=gi:5031662 /UG=Hs.153910 DiGeorge syndrome critical region gene 6 /FL=gb:AF228707.1 gb:NM_005675.1 NM_005675 DiGeorge syndrome critical region gene 6 /// DiGeorge syndrome critical region gene 6-like DGCR6 /// DGCR6L 8214 /// 85359 NM_005675 /// NM_033257 0007155 // cell adhesion // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 208025_s_at NM_003483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003483.2 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein isoform I-C (HMGIC), mRNA. /FEA=mRNA /GEN=HMGIC /PROD=high-mobility group (nonhistone chromosomal)protein isoform I-C /DB_XREF=gi:6631086 /FL=gb:NM_003483.2 NM_003483 high mobility group AT-hook 2 HMGA2 8091 NM_001015886 /// NM_003483 /// NM_003484 /// XM_005269164 /// XM_006719620 /// XR_245958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003131 // mesodermal-endodermal cell signaling // inferred from mutant phenotype /// 0006284 // base-excision repair // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010564 // regulation of cell cycle process // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031052 // chromosome breakage // inferred from direct assay /// 0031507 // heterochromatin assembly // inferred from direct assay /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035978 // histone H2A-S139 phosphorylation // inferred from direct assay /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from direct assay /// 0035987 // endodermal cell differentiation // inferred from mutant phenotype /// 0035988 // chondrocyte proliferation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045444 // fat cell differentiation // inferred from mutant phenotype /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from mutant phenotype /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from mutant phenotype /// 0048863 // stem cell differentiation // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0060123 // regulation of growth hormone secretion // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0090276 // regulation of peptide hormone secretion // inferred from electronic annotation /// 0090402 // oncogene-induced cell senescence // inferred from direct assay /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // traceable author statement /// 2000648 // positive regulation of stem cell proliferation // inferred from direct assay /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000685 // positive regulation of cellular response to X-ray // inferred from direct assay /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay /// 2001033 // negative regulation of double-strand break repair via nonhomologous end joining // inferred from direct assay /// 2001038 // regulation of cellular response to drug // inferred from direct assay 0000228 // nuclear chromosome // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032993 // protein-DNA complex // inferred from direct assay /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003680 // AT DNA binding // inferred from direct assay /// 0003680 // AT DNA binding // inferred from mutant phenotype /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035497 // cAMP response element binding // inferred from direct assay /// 0035500 // MH2 domain binding // inferred from direct assay /// 0035501 // MH1 domain binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from mutant phenotype 208026_at NM_003540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003540.2 /DEF=Homo sapiens H4 histone family, member C (H4FC), mRNA. /FEA=mRNA /GEN=H4FC /PROD=H4 histone family, member C /DB_XREF=gi:5579464 /UG=Hs.247816 H4 histone family, member C /FL=gb:NM_003540.2 NM_003540 histone cluster 1, H4f /// histone cluster 1, H4g HIST1H4F /// HIST1H4G 8361 /// 8369 NM_003540 /// NM_003547 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208027_s_at NM_012465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012465.1 /DEF=Homo sapiens tolloid-like 2 (TLL2), mRNA. /FEA=mRNA /GEN=TLL2 /PROD=tolloid-like 2 /DB_XREF=gi:6912723 /FL=gb:NM_012465.1 NM_012465 tolloid-like 2 TLL2 7093 NM_012465 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208028_s_at NM_003996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003996.2 /DEF=Homo sapiens glutathione peroxidase 5 (epididymal androgen-related protein) (GPX5), transcript variant 2, mRNA. /FEA=mRNA /GEN=GPX5 /PROD=glutathione peroxidase 5 precursor, isoform 2 /DB_XREF=gi:6715601 /UG=Hs.248129 glutathione peroxidase 5 (epididymal androgen-related protein) /FL=gb:NM_003996.2 NM_003996 glutathione peroxidase 5 (epididymal androgen-related protein) GPX5 2880 NM_001509 /// NM_003996 0006629 // lipid metabolic process // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 208029_s_at NM_018407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018407.1 /DEF=Homo sapiens putative integral membrane transporter (LC27), mRNA. /FEA=mRNA /GEN=LC27 /PROD=putative integral membrane transporter /DB_XREF=gi:8923827 /FL=gb:NM_018407.1 NM_018407 lysosomal protein transmembrane 4 beta LAPTM4B 55353 NM_018407 0006810 // transport // inferred from electronic annotation 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208030_s_at NM_001119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001119.2 /DEF=Homo sapiens adducin 1 (alpha) (ADD1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ADD1 /PROD=adducin 1 (alpha) isoform a /DB_XREF=gi:7710113 /FL=gb:NM_001119.2 NM_001119 adducin 1 (alpha) ADD1 118 NM_001119 /// NM_001286645 /// NM_014189 /// NM_014190 /// NM_176801 /// XM_005247933 /// XM_005247934 /// XM_005247935 /// XM_005247936 /// XM_005247937 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 208031_s_at NM_000635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000635.1 /DEF=Homo sapiens regulatory factor X, 2 (influences HLA class II expression) (RFX2), mRNA. /FEA=mRNA /GEN=RFX2 /PROD=regulatory factor X, 2 (influences HLA class IIexpression) /DB_XREF=gi:10835184 /UG=Hs.100007 regulatory factor X, 2 (influences HLA class II expression) /FL=gb:NM_000635.1 NM_000635 regulatory factor X, 2 (influences HLA class II expression) RFX2 5990 NM_000635 /// NM_134433 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 208032_s_at NM_000828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000828.1 /DEF=Homo sapiens glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant flop, mRNA. /FEA=mRNA /GEN=GRIA3 /PROD=glutamate receptor precursor isoform flop /DB_XREF=gi:4504114 /UG=Hs.100014 glutamate receptor, ionotrophic, AMPA 3 /FL=gb:NM_000828.1 gb:U10302.1 NM_000828 glutamate receptor, ionotropic, AMPA 3 GRIA3 2892 NM_000828 /// NM_001256743 /// NM_007325 /// NM_181894 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded 208033_s_at NM_006885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006885.1 /DEF=Homo sapiens AT-binding transcription factor 1 (ATBF1), mRNA. /FEA=mRNA /GEN=ATBF1 /PROD=AT-binding transcription factor 1 /DB_XREF=gi:5901893 /UG=Hs.101842 AT-binding transcription factor 1 /FL=gb:D10250.1 gb:NM_006885.1 NM_006885 zinc finger homeobox 3 ZFHX3 463 NM_001164766 /// NM_006885 /// XM_005255957 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208034_s_at NM_003891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003891.1 /DEF=Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein (PROZ), mRNA. /FEA=mRNA /GEN=PROZ /PROD=protein Z, vitamin K-dependent plasmaglycoprotein /DB_XREF=gi:4506120 /UG=Hs.1011 protein Z, vitamin K-dependent plasma glycoprotein /FL=gb:M55670.1 gb:NM_003891.1 NM_003891 protein Z, vitamin K-dependent plasma glycoprotein PROZ 8858 NM_001256134 /// NM_003891 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208035_at NM_000843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000843.2 /DEF=Homo sapiens glutamate receptor, metabotropic 6 (GRM6), mRNA. /FEA=mRNA /GEN=GRM6 /PROD=glutamate receptor, metabotropic 6 precursor /DB_XREF=gi:6006006 /UG=Hs.248131 glutamate receptor, metabotropic 6 /FL=gb:NM_000843.2 NM_000843 glutamate receptor, metabotropic 6 GRM6 2916 NM_000843 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009584 // detection of visible light // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0050953 // sensory perception of light stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0035841 // new growing cell tip // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded /// 0042995 // cell projection // inferred from electronic annotation 0001640 // adenylate cyclase inhibiting G-protein coupled glutamate receptor activity // inferred from electronic annotation /// 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // inferred from mutant phenotype /// 0008066 // glutamate receptor activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction 208036_at NM_001708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001708.1 /DEF=Homo sapiens opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) (OPN1SW), mRNA. /FEA=mRNA /GEN=OPN1SW /PROD=opsin 1 (cone pigments), short-wave-sensitive(color blindness, tritan) /DB_XREF=gi:4502386 /UG=Hs.102119 opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) /FL=gb:NM_001708.1 NM_001708 opsin 1 (cone pigments), short-wave-sensitive OPN1SW 611 NM_001708 0001523 // retinoid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0009881 // photoreceptor activity // inferred from electronic annotation 208037_s_at NM_007164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007164.1 /DEF=Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), mRNA. /FEA=mRNA /GEN=MADCAM1 /PROD=mucosal vascular addressin cell adhesionmolecule 1 /DB_XREF=gi:6005805 /UG=Hs.102598 mucosal vascular addressin cell adhesion molecule 1 /FL=gb:U43628.1 gb:NM_007164.1 NM_007164 mucosal vascular addressin cell adhesion molecule 1 MADCAM1 8174 NM_130760 /// NM_130762 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 208038_at NM_003854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003854.1 /DEF=Homo sapiens interleukin 1 receptor-like 2 (IL1RL2), mRNA. /FEA=mRNA /GEN=IL1RL2 /PROD=interleukin 1 receptor-like 2 /DB_XREF=gi:4504662 /UG=Hs.102865 interleukin 1 receptor-like 2 /FL=gb:AF284434.1 gb:U49065.1 gb:NM_003854.1 NM_003854 interleukin 1 receptor-like 2 IL1RL2 8808 NM_003854 /// XM_005264035 /// XM_005264036 /// XM_006712820 /// XM_006712821 /// XM_006712822 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0070498 // interleukin-1-mediated signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004908 // interleukin-1 receptor activity // traceable author statement /// 0004909 // interleukin-1, Type I, activating receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208039_at NM_003048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003048.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 2 (SLC9A2), mRNA. /FEA=mRNA /GEN=SLC9A2 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 2 /DB_XREF=gi:4507058 /UG=Hs.103132 solute carrier family 9 (sodiumhydrogen exchanger), isoform 2 /FL=gb:NM_003048.1 NM_003048 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // traceable author statement 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from direct assay /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation 208040_s_at NM_000256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000256.2 /DEF=Homo sapiens myosin-binding protein C, cardiac (MYBPC3), mRNA. /FEA=mRNA /GEN=MYBPC3 /PROD=protein C, cardiac /DB_XREF=gi:13325073 /FL=gb:NM_000256.2 NM_000256 myosin binding protein C, cardiac MYBPC3 4607 NM_000256 /// XM_006718238 0002027 // regulation of heart rate // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0006936 // muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0031034 // myosin filament assembly // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0032971 // regulation of muscle filament sliding // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement /// 0005863 // striated muscle myosin thick filament // inferred from direct assay /// 0005863 // striated muscle myosin thick filament // inferred from sequence or structural similarity /// 0014705 // C zone // non-traceable author statement /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // inferred from direct assay /// 0031672 // A band // inferred from direct assay /// 0032982 // myosin filament // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from sequence or structural similarity /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0017022 // myosin binding // inferred from direct assay /// 0031432 // titin binding // non-traceable author statement /// 0032036 // myosin heavy chain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208041_at NM_002929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002929.1 /DEF=Homo sapiens rhodopsin kinase (RHOK), mRNA. /FEA=mRNA /GEN=RHOK /PROD=rhodopsin kinase /DB_XREF=gi:4506528 /UG=Hs.103501 rhodopsin kinase /FL=gb:L77503.1 gb:U63973.1 gb:NM_002929.1 NM_002929 G protein-coupled receptor kinase 1 GRK1 6011 NM_002929 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0008594 // photoreceptor cell morphogenesis // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060060 // post-embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050254 // rhodopsin kinase activity // inferred from direct assay 208042_at NM_013303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013303.1 /DEF=Homo sapiens fetal hypothetical protein (HSU84971), mRNA. /FEA=mRNA /GEN=HSU84971 /PROD=fetal hypothetical protein /DB_XREF=gi:9558744 /UG=Hs.104530 fetal hypothetical protein /FL=gb:U84971.1 gb:NM_013303.1 NM_013303 angiogenic factor with G patch and FHA domains 1 AGGF1 55109 NM_018046 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208043_at NM_020484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020484.1 /DEF=Homo sapiens RAGE binding protein (AF011757), mRNA. /FEA=mRNA /GEN=AF011757 /PROD=RAGE binding protein /DB_XREF=gi:10048411 /UG=Hs.105937 RAGE binding protein /FL=gb:NM_020484.1 gb:AF011757.1 NM_020484 208044_s_at NM_006238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006238.1 /DEF=Homo sapiens peroxisome proliferative activated receptor, delta (PPARD), mRNA. /FEA=mRNA /GEN=PPARD /PROD=peroxisome proliferative activated receptor,delta /DB_XREF=gi:5453939 /UG=Hs.106415 peroxisome proliferative activated receptor, delta /FL=gb:L07592.1 gb:NM_006238.1 NM_006238 peroxisome proliferator-activated receptor delta PPARD 5467 NM_001171818 /// NM_001171819 /// NM_001171820 /// NM_006238 /// NM_177435 /// XM_005249193 /// XM_005249194 /// XM_006715120 /// XM_006715121 /// XM_006715122 /// XM_006715123 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006776 // vitamin A metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // traceable author statement /// 0009299 // mRNA transcription // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0015908 // fatty acid transport // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032966 // negative regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // non-traceable author statement /// 0045684 // positive regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046697 // decidualization // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051546 // keratinocyte migration // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005504 // fatty acid binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation /// 0070539 // linoleic acid binding // inferred from direct assay 208045_at NM_005129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005129.1 /DEF=Homo sapiens surfactant protein A binding protein (SPAR), mRNA. /FEA=mRNA /GEN=SPAR /PROD=surfactant protein A binding protein /DB_XREF=gi:4827017 /UG=Hs.1071 surfactant protein A binding protein /FL=gb:L10123.1 gb:NM_005129.1 NM_005129 208046_at NM_003538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003538.2 /DEF=Homo sapiens H4 histone family, member A (H4FA), mRNA. /FEA=mRNA /GEN=H4FA /PROD=H4 histone family, member A /DB_XREF=gi:5579462 /UG=Hs.248178 H4 histone family, member A /FL=gb:NM_003538.2 NM_003538 histone cluster 1, H4a HIST1H4A 8359 NM_003538 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208047_s_at NM_005966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005966.1 /DEF=Homo sapiens NGFI-A binding protein 1 (ERG1 binding protein 1) (NAB1), mRNA. /FEA=mRNA /GEN=NAB1 /PROD=NGFI-A binding protein 1 (ERG1 binding protein1) /DB_XREF=gi:5174604 /UG=Hs.107474 NGFI-A binding protein 1 (ERG1 binding protein 1) /FL=gb:U47007.1 gb:NM_005966.1 NM_005966 NGFI-A binding protein 1 (EGR1 binding protein 1) NAB1 4664 NM_005966 /// XM_005246579 /// XM_005246580 /// XM_005246581 /// XM_005246582 /// XM_005246583 /// XM_005246584 /// XM_005246585 /// XM_005246586 /// XM_005246587 /// XM_006712540 0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0008134 // transcription factor binding // inferred from electronic annotation 208048_at NM_015727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015727.1 /DEF=Homo sapiens tachykinin receptor 1 (TACR1), transcript variant short, mRNA. /FEA=mRNA /GEN=TACR1 /PROD=tachykinin receptor 1, isoform short /DB_XREF=gi:7669545 /UG=Hs.1080 tachykinin receptor 1 /FL=gb:M84426.1 gb:NM_015727.1 NM_015727 tachykinin receptor 1 TACR1 6869 NM_001058 /// NM_015727 0002118 // aggressive behavior // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0003051 // angiotensin-mediated drinking behavior // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007638 // mechanosensory behavior // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0010193 // response to ozone // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035106 // operant conditioning // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046878 // positive regulation of saliva secretion // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016496 // substance P receptor activity // inferred from electronic annotation 208049_s_at NM_015727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015727.1 /DEF=Homo sapiens tachykinin receptor 1 (TACR1), transcript variant short, mRNA. /FEA=mRNA /GEN=TACR1 /PROD=tachykinin receptor 1, isoform short /DB_XREF=gi:7669545 /UG=Hs.1080 tachykinin receptor 1 /FL=gb:M84426.1 gb:NM_015727.1 NM_015727 tachykinin receptor 1 TACR1 6869 NM_001058 /// NM_015727 0002118 // aggressive behavior // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0003051 // angiotensin-mediated drinking behavior // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007638 // mechanosensory behavior // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0010193 // response to ozone // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035106 // operant conditioning // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046878 // positive regulation of saliva secretion // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016496 // substance P receptor activity // inferred from electronic annotation 208050_s_at NM_001224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001224.1 /DEF=Homo sapiens caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) (CASP2), mRNA. /FEA=mRNA /GEN=CASP2 /PROD=caspase 2, apoptosis-related cysteine protease(neural precursor cell expressed, developmentallydown-regulated 2) /DB_XREF=gi:4502574 /UG=Hs.108131 caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) /FL=gb:NM_001224.1 gb:U13022.1 NM_001224 caspase 2, apoptosis-related cysteine peptidase CASP2 835 NM_001224 /// NM_032982 /// NM_032983 0001554 // luteolysis // inferred from electronic annotation /// 0003407 // neural retina development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 208051_s_at NM_006451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006451.1 /DEF=Homo sapiens polyadenylate binding protein-interacting protein 1 (PAIP1), mRNA. /FEA=mRNA /GEN=PAIP1 /PROD=polyadenylate binding protein-interactingprotein 1 /DB_XREF=gi:5453845 /UG=Hs.109643 polyadenylate binding protein-interacting protein 1 /FL=gb:AF013758.1 gb:NM_006451.1 NM_006451 poly(A) binding protein interacting protein 1 PAIP1 10605 NM_006451 /// NM_182789 /// NM_183323 /// XM_005248230 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 208052_x_at NM_001815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001815.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), mRNA. /FEA=mRNA /GEN=CEACAM3 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 3 /DB_XREF=gi:4502792 /UG=Hs.11 carcinoembryonic antigen-related cell adhesion molecule 3 /FL=gb:L00693.1 gb:NM_001815.1 NM_001815 carcinoembryonic antigen-related cell adhesion molecule 3 CEACAM3 1084 NM_001277163 /// NM_001815 /// NR_102333 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 208053_at NM_001522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001522.1 /DEF=Homo sapiens guanylate cyclase 2F, retinal (GUCY2F), mRNA. /FEA=mRNA /GEN=GUCY2F /PROD=guanylate cyclase 2F /DB_XREF=gi:4504218 /UG=Hs.123074 guanylate cyclase 2F, retinal /FL=gb:NM_001522.1 gb:L37378.1 NM_001522 guanylate cyclase 2F, retinal GUCY2F 2986 NM_001522 /// XR_244473 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007168 // receptor guanylyl cyclase signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005640 // nuclear outer membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208054_at NM_015601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015601.1 /DEF=Homo sapiens DKFZP564G092 protein (DKFZP564G092), mRNA. /FEA=mRNA /GEN=DKFZP564G092 /PROD=DKFZP564G092 protein /DB_XREF=gi:7661611 /UG=Hs.11123 DKFZP564G092 protein /FL=gb:NM_015601.1 NM_015601 HECT and RLD domain containing E3 ubiquitin protein ligase 4 HERC4 26091 NM_001017972 /// NM_001278185 /// NM_001278186 /// NM_001278187 /// NM_015601 /// NM_022079 /// XM_006717751 /// XM_006717752 /// XM_006717753 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 208055_s_at NM_015601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015601.1 /DEF=Homo sapiens DKFZP564G092 protein (DKFZP564G092), mRNA. /FEA=mRNA /GEN=DKFZP564G092 /PROD=DKFZP564G092 protein /DB_XREF=gi:7661611 /UG=Hs.11123 DKFZP564G092 protein /FL=gb:NM_015601.1 NM_015601 HECT and RLD domain containing E3 ubiquitin protein ligase 4 HERC4 26091 NM_001017972 /// NM_001278185 /// NM_001278186 /// NM_001278187 /// NM_015601 /// NM_022079 /// XM_006717751 /// XM_006717752 /// XM_006717753 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 208056_s_at NM_005187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005187.2 /DEF=Homo sapiens core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), mRNA. /FEA=mRNA /GEN=CBFA2T3 /PROD=core-binding factor, runt domain, alpha subunit2; translocated to, 3 /DB_XREF=gi:7427510 /UG=Hs.110099 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 /FL=gb:NM_005187.2 NM_005187 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 CBFA2T3 863 NM_005187 /// NM_175931 /// XM_005256323 /// XM_006721319 /// XM_006721320 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030851 // granulocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208057_s_at D14827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D14827.1 /DEF=Human mRNA for Tax helper protein 1, complete cds. /FEA=mRNA /GEN=THP1 /PROD=Tax helper protein 1 /DB_XREF=gi:439899 /UG=Hs.111867 GLI-Kruppel family member GLI2 /FL=gb:NM_030380.1 gb:AB007296.1 gb:D14827.1 D14827 GLI family zinc finger 2 GLI2 2736 NM_005270 /// NM_030379 /// NM_030380 /// NM_030381 /// XM_006712422 /// XM_006712423 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from direct assay /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007418 // ventral midline development // inferred from sequence or structural similarity /// 0007442 // hindgut morphogenesis // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009913 // epidermal cell differentiation // inferred from direct assay /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from sequence or structural similarity /// 0021508 // floor plate formation // inferred from sequence or structural similarity /// 0021513 // spinal cord dorsal/ventral patterning // inferred from sequence or structural similarity /// 0021517 // ventral spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from sequence or structural similarity /// 0021775 // smoothened signaling pathway involved in ventral spinal cord interneuron specification // inferred from sequence or structural similarity /// 0021776 // smoothened signaling pathway involved in spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021938 // smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation // inferred from electronic annotation /// 0021965 // spinal cord ventral commissure morphogenesis // inferred from sequence or structural similarity /// 0021983 // pituitary gland development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035295 // tube development // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0060032 // notochord regression // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0072372 // primary cilium // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208058_s_at NM_002409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002409.2 /DEF=Homo sapiens mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (MGAT3), mRNA. /FEA=mRNA /GEN=MGAT3 /PROD=mannosyl (beta-1,4-)-glycoproteinbeta-1,4-N-acetylglucosaminyltransferase /DB_XREF=gi:6031184 /UG=Hs.112 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase /FL=gb:NM_002409.2 NM_002409 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase MGAT3 4248 NM_001098270 /// NM_002409 /// XM_005261608 /// XM_005261609 /// XM_006724252 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003830 // beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 208059_at NM_005201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005201.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 8 (CCR8), mRNA. /FEA=mRNA /GEN=CCR8 /PROD=chemokine (C-C motif) receptor 8 /DB_XREF=gi:4885120 /UG=Hs.113222 chemokine (C-C motif) receptor 8 /FL=gb:D49919.1 gb:NM_005201.1 NM_005201 chemokine (C-C motif) receptor 8 CCR8 1237 NM_005201 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0015026 // coreceptor activity // traceable author statement /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 208060_at NM_002584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002584.1 /DEF=Homo sapiens paired box gene 7 (PAX7), transcript variant 1, mRNA. /FEA=mRNA /GEN=PAX7 /PROD=paired box gene 7, isoform 1 /DB_XREF=gi:4505618 /UG=Hs.113253 paired box gene 7 /FL=gb:NM_002584.1 gb:NM_013945.1 NM_002584 paired box 7 PAX7 5081 NM_001135254 /// NM_002584 /// NM_013945 /// XM_005245884 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010453 // regulation of cell fate commitment // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014813 // satellite cell commitment // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0031062 // positive regulation of histone methylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208061_at NM_015877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015877.1 /DEF=Homo sapiens Kruppel-associated box protein (LOC51045), mRNA. /FEA=mRNA /GEN=LOC51045 /PROD=Kruppel-associated box protein /DB_XREF=gi:7705665 /UG=Hs.113263 Kruppel-associated box protein /FL=gb:AF028840.1 gb:NM_015877.1 NM_015877 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208062_s_at NM_013984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013984.1 /DEF=Homo sapiens neuregulin 2 (NRG2), transcript variant 5, mRNA. /FEA=mRNA /GEN=NRG2 /PROD=neuregulin 2 isoform 5 /DB_XREF=gi:7669533 /UG=Hs.113264 neuregulin 2 /FL=gb:NM_013984.1 gb:NM_013985.1 NM_013984 neuregulin 2 NRG2 9542 NM_001184935 /// NM_004883 /// NM_013981 /// NM_013982 /// NM_013983 /// NM_013984 /// NM_013985 /// XM_005268533 /// XM_006714808 /// XM_006714809 /// XM_006714810 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 208063_s_at NM_006615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006615.1 /DEF=Homo sapiens calpain 9 (nCL-4) (CAPN9), mRNA. /FEA=mRNA /GEN=CAPN9 /PROD=calpain 9 /DB_XREF=gi:5729757 /UG=Hs.113292 calpain 9 (nCL-4) /FL=gb:AF022799.1 gb:NM_006615.1 NM_006615 calpain 9 CAPN9 10753 NM_006615 /// NM_016452 /// XM_005273010 /// XR_426915 0006508 // proteolysis // not recorded /// 0007586 // digestion // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208064_s_at NM_015879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015879.1 /DEF=Homo sapiens sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) (SIAT8C), mRNA. /FEA=mRNA /GEN=SIAT8C /PROD=sialyltransferase 8C(alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) /DB_XREF=gi:7705667 /UG=Hs.114316 sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) /FL=gb:AF004668.2 gb:NM_015879.1 NM_015879 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8SIA3 51046 NM_015879 0001574 // ganglioside biosynthetic process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from direct assay /// 0006491 // N-glycan processing // inferred from direct assay /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred by curator 208065_at NM_015879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015879.1 /DEF=Homo sapiens sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) (SIAT8C), mRNA. /FEA=mRNA /GEN=SIAT8C /PROD=sialyltransferase 8C(alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) /DB_XREF=gi:7705667 /UG=Hs.114316 sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase) /FL=gb:AF004668.2 gb:NM_015879.1 NM_015879 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8SIA3 51046 NM_015879 0001574 // ganglioside biosynthetic process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from direct assay /// 0006491 // N-glycan processing // inferred from direct assay /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred by curator 208066_s_at NM_001514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001514.2 /DEF=Homo sapiens general transcription factor IIB (GTF2B), mRNA. /FEA=mRNA /GEN=GTF2B /PROD=general transcription factor IIB /DB_XREF=gi:13435384 /FL=gb:NM_001514.2 NM_001514 general transcription factor IIB GTF2B 2959 NM_001514 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0001047 // core promoter binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction 208067_x_at NM_007125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007125.1 /DEF=Homo sapiens ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome (UTY), mRNA. /FEA=mRNA /GEN=UTY /PROD=ubiquitously transcribed tetratricopeptiderepeat gene, Y chromosome /DB_XREF=gi:6005939 /UG=Hs.115277 ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome /FL=gb:AF000996.1 gb:NM_007125.1 NM_007125 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked UTY 7404 NM_001258249 /// NM_001258250 /// NM_001258251 /// NM_001258252 /// NM_001258253 /// NM_001258254 /// NM_001258255 /// NM_001258256 /// NM_001258257 /// NM_001258258 /// NM_001258259 /// NM_001258260 /// NM_001258261 /// NM_001258262 /// NM_001258263 /// NM_001258264 /// NM_001258265 /// NM_001258266 /// NM_001258267 /// NM_001258268 /// NM_001258269 /// NM_001258270 /// NM_007125 /// NM_182659 /// NM_182660 /// NR_047596 /// NR_047597 /// NR_047598 /// NR_047599 /// NR_047600 /// NR_047601 /// NR_047602 /// NR_047603 /// NR_047604 /// NR_047605 /// NR_047606 /// NR_047607 /// NR_047608 /// NR_047609 /// NR_047610 /// NR_047611 /// NR_047612 /// NR_047613 /// NR_047614 /// NR_047615 /// NR_047616 /// NR_047617 /// NR_047618 /// NR_047619 /// NR_047620 /// NR_047621 /// NR_047622 /// NR_047623 /// NR_047624 /// NR_047625 /// NR_047626 /// NR_047627 /// NR_047628 /// NR_047629 /// NR_047630 /// NR_047631 /// NR_047632 /// NR_047633 /// NR_047634 /// NR_047635 /// NR_047636 /// NR_047637 /// NR_047638 /// NR_047639 /// NR_047640 /// NR_047641 /// NR_047642 /// NR_047643 /// NR_047644 /// NR_047645 /// NR_047646 /// NR_047647 /// XM_005262518 /// XM_006724875 /// XM_006724876 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031935 // regulation of chromatin silencing // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from electronic annotation /// 0086003 // cardiac muscle cell contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 208068_x_at NM_022562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022562.1 /DEF=Homo sapiens growth hormone 1 (GH1), transcript variant 5, mRNA. /FEA=mRNA /GEN=GH1 /PROD=growth hormone 1, isoform 5 /DB_XREF=gi:13027819 /UG=Hs.115352 growth hormone 1 /FL=gb:NM_022562.1 NM_022562 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 /// growth hormone 2 CSH1 /// CSHL1 /// GH1 /// GH2 1442 /// 1444 /// 2688 /// 2689 NM_000515 /// NM_001317 /// NM_001318 /// NM_002059 /// NM_022556 /// NM_022557 /// NM_022558 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208069_x_at NM_022561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022561.1 /DEF=Homo sapiens growth hormone 1 (GH1), transcript variant 4, mRNA. /FEA=mRNA /GEN=GH1 /PROD=growth hormone 1, isoform 4 precursor /DB_XREF=gi:13027817 /UG=Hs.115352 growth hormone 1 /FL=gb:NM_022561.1 NM_022561 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 /// growth hormone 2 CSH1 /// CSHL1 /// GH1 /// GH2 1442 /// 1444 /// 2688 /// 2689 NM_000515 /// NM_001317 /// NM_001318 /// NM_002059 /// NM_022556 /// NM_022557 /// NM_022558 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208070_s_at NM_002912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002912.1 /DEF=Homo sapiens REV3 (yeast homolog)-like, catalytic subunit of DNA polymerase zeta (REV3L), mRNA. /FEA=mRNA /GEN=REV3L /PROD=REV3 (yeast homolog)-like, catalytic subunit ofDNA polymerase zeta /DB_XREF=gi:4506482 /UG=Hs.115521 REV3 (yeast homolog)-like, catalytic subunit of DNA polymerase zeta /FL=gb:AF078695.1 gb:NM_002912.1 gb:AF179428.1 NM_002912 REV3-like, polymerase (DNA directed), zeta, catalytic subunit REV3L 5980 NM_001286431 /// NM_001286432 /// NM_002912 /// XM_005267090 /// XM_005267091 /// XM_006715543 /// XM_006715544 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0019985 // translesion synthesis // not recorded 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0016035 // zeta DNA polymerase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 208071_s_at NM_021708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021708.1 /DEF=Homo sapiens leukocyte-associated Ig-like receptor 1 (LAIR1), transcript variant d, mRNA. /FEA=mRNA /GEN=LAIR1 /PROD=leukocyte-associated Ig-like receptor 1, isoformd precursor /DB_XREF=gi:11231178 /UG=Hs.115808 leukocyte-associated Ig-like receptor 1 /FL=gb:AF251510.2 gb:NM_021708.1 NM_021708 leukocyte-associated immunoglobulin-like receptor 1 LAIR1 3903 NM_001289023 /// NM_001289025 /// NM_001289026 /// NM_001289027 /// NM_002287 /// NM_021706 /// NM_021708 /// NR_110279 /// NR_110280 /// XM_005258920 /// XM_005258924 /// XM_005277109 /// XM_005277111 /// XM_005277309 /// XM_006726158 0002376 // immune system process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208072_s_at NM_003648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003648.1 /DEF=Homo sapiens diacylglycerol kinase, delta (130kD) (DGKD), mRNA. /FEA=mRNA /GEN=DGKD /PROD=diacylglycerol kinase, delta (130kD) /DB_XREF=gi:4503310 /UG=Hs.115907 diacylglycerol kinase, delta (130kD) /FL=gb:D73409.1 gb:NM_003648.1 NM_003648 diacylglycerol kinase, delta 130kDa DGKD 8527 NM_003648 /// NM_152879 /// XM_005246107 /// XM_005246108 /// XM_005246109 /// XM_005246110 /// XR_427118 /// XR_427119 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0046339 // diacylglycerol metabolic process // inferred by curator /// 0046339 // diacylglycerol metabolic process // non-traceable author statement /// 0051260 // protein homooligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from direct assay /// 0004143 // diacylglycerol kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 208073_x_at NM_003316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003316.1 /DEF=Homo sapiens tetratricopeptide repeat domain 3 (TTC3), mRNA. /FEA=mRNA /GEN=TTC3 /PROD=tetratricopeptide repeat domain 3 /DB_XREF=gi:10835036 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:NM_003316.1 gb:D84295.1 NM_003316 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208074_s_at NM_021575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021575.1 /DEF=Homo sapiens adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17delta, mRNA. /FEA=mRNA /GEN=AP2S1 /PROD=adaptor-related protein complex 2, sigma 1subunit, isoform AP17delta /DB_XREF=gi:11038642 /UG=Hs.119591 adaptor-related protein complex 2, sigma 1 subunit /FL=gb:NM_021575.1 NM_021575 adaptor-related protein complex 2, sigma 1 subunit AP2S1 1175 NM_004069 /// NM_021575 /// XM_005258499 /// XM_005258500 /// XM_006723004 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030100 // regulation of endocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005215 // transporter activity // non-traceable author statement /// 0008565 // protein transporter activity // non-traceable author statement 208075_s_at NM_006273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006273.2 /DEF=Homo sapiens small inducible cytokine A7 (monocyte chemotactic protein 3) (SCYA7), mRNA. /FEA=mRNA /GEN=SCYA7 /PROD=monocyte chemotactic protein 3 precursor /DB_XREF=gi:13435401 /FL=gb:NM_006273.2 NM_006273 chemokine (C-C motif) ligand 7 CCL7 6354 NM_006273 0002548 // monocyte chemotaxis // inferred by curator /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031727 // CCR2 chemokine receptor binding // inferred from electronic annotation 208076_at NM_003539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003539.2 /DEF=Homo sapiens H4 histone family, member B (H4FB), mRNA. /FEA=mRNA /GEN=H4FB /PROD=H4 histone family, member B /DB_XREF=gi:5579463 /UG=Hs.248179 H4 histone family, member B /FL=gb:NM_003539.2 NM_003539 histone cluster 1, H4d HIST1H4D 8360 NM_003539 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208077_at NM_014126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014126.1 /DEF=Homo sapiens PRO0365 protein (PRO0365), mRNA. /FEA=mRNA /GEN=PRO0365 /PROD=PRO0365 protein /DB_XREF=gi:7662547 /UG=Hs.249613 PRO0365 protein /FL=gb:AF090921.1 gb:NM_014126.1 NM_014126 chromosome 9 open reading frame 38 C9orf38 29044 NM_014126 /// XR_108926 /// XR_113207 /// XR_171764 208078_s_at NM_030751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030751.1 /DEF=Homo sapiens transcription factor 8 (represses interleukin 2 expression) (TCF8), mRNA. /FEA=mRNA /GEN=TCF8 /PROD=transcription factor 8 (represses interleukin 2expression) /DB_XREF=gi:13540478 /FL=gb:NM_030751.1 NM_030751 salt-inducible kinase 1 SIK1 150094 NM_173354 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010464 // regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0010868 // negative regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043276 // anoikis // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048513 // organ development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 2000210 // positive regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070888 // E-box binding // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity /// 0071889 // 14-3-3 protein binding // inferred from direct assay 208079_s_at NM_003158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003158.1 /DEF=Homo sapiens serinethreonine kinase 6 (STK6), mRNA. /FEA=mRNA /GEN=STK6 /PROD=serinethreonine kinase 6 /DB_XREF=gi:4507278 /UG=Hs.250822 serinethreonine kinase 6 /FL=gb:D84212.1 gb:NM_003158.1 NM_003158 aurora kinase A AURKA 6790 NM_003600 /// NM_198433 /// NM_198434 /// NM_198435 /// NM_198436 /// NM_198437 /// XM_005260534 /// XM_006723871 /// XM_006723872 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043146 // spindle stabilization // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // traceable author statement /// 0046605 // regulation of centrosome cycle // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 208080_at NM_003158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003158.1 /DEF=Homo sapiens serinethreonine kinase 6 (STK6), mRNA. /FEA=mRNA /GEN=STK6 /PROD=serinethreonine kinase 6 /DB_XREF=gi:4507278 /UG=Hs.250822 serinethreonine kinase 6 /FL=gb:D84212.1 gb:NM_003158.1 NM_003158 aurora kinase A AURKA 6790 NM_003600 /// NM_198433 /// NM_198434 /// NM_198435 /// NM_198436 /// NM_198437 /// XM_005260534 /// XM_006723871 /// XM_006723872 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043146 // spindle stabilization // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // traceable author statement /// 0046605 // regulation of centrosome cycle // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 208081_s_at NM_030824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030824.1 /DEF=Homo sapiens hypothetical protein FLJ14356 (FLJ14356), mRNA. /FEA=mRNA /GEN=FLJ14356 /PROD=hypothetical protein FLJ14356 /DB_XREF=gi:13540500 /FL=gb:NM_030824.1 NM_030824 zinc finger protein 442 ZNF442 79973 NM_030824 /// XM_006722907 /// XM_006722908 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208082_x_at NM_030757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030757.1 /DEF=Homo sapiens makorin, ring finger protein, 4 (MKRN4), mRNA. /FEA=mRNA /GEN=MKRN4 /PROD=makorin, ring finger protein, 4 /DB_XREF=gi:13540508 /FL=gb:NM_030757.1 NM_030757 /// makorin ring finger protein 4, pseudogene MKRN4P /// MKRN4P 208083_s_at NM_000888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000888.3 /DEF=Homo sapiens integrin, beta 6 (ITGB6), mRNA. /FEA=mRNA /GEN=ITGB6 /PROD=integrin, beta 6 /DB_XREF=gi:9966771 /UG=Hs.123125 integrin, beta 6 /FL=gb:M35198.3 gb:NM_000888.3 NM_000888 integrin, beta 6 /// uncharacterized LOC100505984 ITGB6 /// LOC100505984 3694 /// 100505984 NM_000888 /// NM_001282353 /// NM_001282354 /// NM_001282355 /// NM_001282388 /// NM_001282389 /// NM_001282390 /// NR_103775 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation 208084_at NM_000888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000888.3 /DEF=Homo sapiens integrin, beta 6 (ITGB6), mRNA. /FEA=mRNA /GEN=ITGB6 /PROD=integrin, beta 6 /DB_XREF=gi:9966771 /UG=Hs.123125 integrin, beta 6 /FL=gb:M35198.3 gb:NM_000888.3 NM_000888 integrin, beta 6 /// uncharacterized LOC100505984 ITGB6 /// LOC100505984 3694 /// 100505984 NM_000888 /// NM_001282353 /// NM_001282354 /// NM_001282355 /// NM_001282388 /// NM_001282389 /// NM_001282390 /// NR_103775 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation 208085_s_at NM_006125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006125.1 /DEF=Homo sapiens Rho GTPase activating protein 6 (ARHGAP6), transcript variant 3, mRNA. /FEA=mRNA /GEN=ARHGAP6 /PROD=Rho GTPase activating protein 6 isoform 3 /DB_XREF=gi:7382483 /UG=Hs.250830 Rho GTPase activating protein 6 /FL=gb:AF012272.2 gb:NM_006125.1 NM_006125 Rho GTPase activating protein 6 ARHGAP6 395 NM_001174 /// NM_001287242 /// NM_006125 /// NM_013422 /// NM_013423 /// NM_013427 /// NR_109776 /// XM_005274505 /// XM_005274506 /// XM_005274507 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from direct assay /// 0030041 // actin filament polymerization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 208086_s_at M92650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M92650.1 /DEF=Human Duchenne muscular dystrophy (DMD) mRNA, complete cds. /FEA=mRNA /GEN=DMD /DB_XREF=gi:181598 /UG=Hs.169470 dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 /FL=gb:M92650.1 gb:NM_004018.1 M92650 dystrophin DMD 1756 NM_000109 /// NM_004006 /// NM_004007 /// NM_004009 /// NM_004010 /// NM_004011 /// NM_004012 /// NM_004013 /// NM_004014 /// NM_004015 /// NM_004016 /// NM_004017 /// NM_004018 /// NM_004019 /// NM_004020 /// NM_004021 /// NM_004022 /// NM_004023 /// XM_006724468 /// XM_006724469 /// XM_006724470 /// XM_006724471 /// XM_006724472 /// XM_006724473 /// XM_006724474 /// XM_006724475 /// XM_006724476 /// XR_430491 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014819 // regulation of skeletal muscle contraction // inferred from sequence or structural similarity /// 0014904 // myotube cell development // inferred from electronic annotation /// 0021629 // olfactory nerve structural organization // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity /// 0044458 // motile cilium assembly // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051647 // nucleus localization // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060857 // establishment of glial blood-brain barrier // inferred from electronic annotation /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0090287 // regulation of cellular response to growth factor stimulus // inferred from mutant phenotype /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 2000169 // regulation of peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // non-traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0017022 // myosin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from sequence or structural similarity 208087_s_at NM_030776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030776.1 /DEF=Homo sapiens tumor stroma and activated macrophage protein DLM-1 (DLM1), mRNA. /FEA=mRNA /GEN=DLM1 /PROD=tumor stroma and activated macrophage proteinDLM-1 /DB_XREF=gi:13540544 /FL=gb:NM_030776.1 NM_030776 Z-DNA binding protein 1 ZBP1 81030 NM_001160417 /// NM_001160418 /// NM_001160419 /// NM_030776 /// XM_006723878 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003692 // left-handed Z-DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208088_s_at NM_030787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030787.1 /DEF=Homo sapiens factor H-related protein 5 (FHR5), mRNA. /FEA=mRNA /GEN=FHR5 /PROD=factor H-related protein 5 /DB_XREF=gi:13540562 /FL=gb:NM_030787.1 NM_030787 complement factor H-related 5 CFHR5 81494 NM_030787 0006957 // complement activation, alternative pathway // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 208089_s_at NM_030794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030794.1 /DEF=Homo sapiens hypothetical protein FLJ21007 (FLJ21007), mRNA. /FEA=mRNA /GEN=FLJ21007 /PROD=hypothetical protein FLJ21007 /DB_XREF=gi:13540575 /FL=gb:NM_030794.1 NM_030794 tudor domain containing 3 TDRD3 81550 NM_001146070 /// NM_001146071 /// NM_030794 /// XM_005266556 /// XM_005266557 /// XM_005266558 /// XM_005266560 /// XR_429220 /// XR_429221 0006397 // mRNA processing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208090_s_at NM_000658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000658.1 /DEF=Homo sapiens autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy) (AIRE), transcript variant AIRE-2, mRNA. /FEA=mRNA /GEN=AIRE /PROD=autoimmune regulator AIRE isoform 2 /DB_XREF=gi:4557292 /UG=Hs.129829 autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy) /FL=gb:AB006683.1 gb:NM_000658.1 NM_000658 autoimmune regulator AIRE 326 NM_000383 /// NM_000658 /// NM_000659 /// XM_005261110 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208091_s_at NM_030796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030796.1 /DEF=Homo sapiens hypothetical protein DKFZp564K0822 (DKFZP564K0822), mRNA. /FEA=mRNA /GEN=DKFZP564K0822 /PROD=hypothetical protein DKFZp564K0822 /DB_XREF=gi:13540577 /FL=gb:NM_030796.1 NM_030796 vesicular, overexpressed in cancer, prosurvival protein 1 VOPP1 81552 NM_001284282 /// NM_001284283 /// NM_001284284 /// NM_030796 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0031301 // integral component of organelle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype 208092_s_at NM_030797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030797.1 /DEF=Homo sapiens hypothetical protein DKFZp566A1524 (DKFZP566A1524), mRNA. /FEA=mRNA /GEN=DKFZP566A1524 /PROD=hypothetical protein DKFZp566A1524 /DB_XREF=gi:13540579 /FL=gb:NM_030797.1 NM_030797 family with sequence similarity 49, member A FAM49A 81553 NM_030797 /// XM_005262630 /// XM_006712108 0005622 // intracellular // inferred from direct assay 208093_s_at NM_030808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030808.1 /DEF=Homo sapiens LIS1-interacting protein NUDEL; endooligopeptidase A (NUDEL), mRNA. /FEA=mRNA /GEN=NUDEL /PROD=LIS1-interacting protein NUDEL;endooligopeptidase A /DB_XREF=gi:13540599 /FL=gb:NM_030808.1 NM_030808 nudE neurodevelopment protein 1-like 1 NDEL1 81565 NM_001025579 /// NM_030808 /// XM_005256806 /// XM_006721580 /// XM_006721581 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032864 // activation of Cdc42 GTPase activity // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048680 // positive regulation of axon regeneration // inferred from electronic annotation /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0070012 // oligopeptidase activity // inferred from electronic annotation 208094_s_at NM_030818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030818.1 /DEF=Homo sapiens hypothetical protein MGC10471 (MGC10471), mRNA. /FEA=mRNA /GEN=MGC10471 /PROD=hypothetical protein MGC10471 /DB_XREF=gi:13540613 /FL=gb:NM_030818.1 NM_030818 coiled-coil domain containing 130 CCDC130 81576 NM_030818 /// XM_005260085 /// XM_005260086 /// XM_005260087 /// XM_005260088 /// XM_006722914 0009615 // response to virus // inferred from expression pattern 0005515 // protein binding // inferred from physical interaction 208095_s_at NM_001222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001222.1 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase (CaM kinase) II gamma (CAMK2G), mRNA. /FEA=mRNA /GEN=CAMK2G /PROD=calciumcalmodulin-dependent protein kinase (CaMkinase) II gamma /DB_XREF=gi:4502554 /UG=Hs.250857 calciumcalmodulin-dependent protein kinase (CaM kinase) II gamma /FL=gb:U81554.1 gb:NM_001222.1 NM_001222 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005047 // signal recognition particle binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208096_s_at NM_030820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030820.1 /DEF=Homo sapiens hypothetical protein DKFZp564B052 (DKFZp564B052), mRNA. /FEA=mRNA /GEN=DKFZp564B052 /PROD=hypothetical protein DKFZp564B052 /DB_XREF=gi:13540617 /FL=gb:NM_030820.1 NM_030820 collagen, type XXI, alpha 1 COL21A1 81578 NM_030820 /// XM_006715223 /// XM_006715224 /// XM_006715225 /// XR_241922 /// XR_241923 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 208097_s_at NM_030755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030755.1 /DEF=Homo sapiens thioredoxin-related transmembrane protein (TMX), mRNA. /FEA=mRNA /GEN=TMX /PROD=thioredoxin-related transmembrane protein /DB_XREF=gi:13559515 /FL=gb:NM_030755.1 NM_030755 thioredoxin-related transmembrane protein 1 TMX1 81542 NM_030755 0006260 // DNA replication // non-traceable author statement /// 0006457 // protein folding // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045321 // leukocyte activation // non-traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045927 // positive regulation of growth // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded /// 0015036 // disulfide oxidoreductase activity // inferred from direct assay /// 0030612 // arsenate reductase (thioredoxin) activity // non-traceable author statement 208098_at NM_030876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030876.1 /DEF=Homo sapiens olfactory receptor, family 5, subfamily V member 1 (OR5V1), mRNA. /FEA=mRNA /GEN=OR5V1 /PROD=olfactory receptor, family 5, subfamily V member1 /DB_XREF=gi:13562083 /FL=gb:NM_030876.1 NM_030876 olfactory receptor, family 12, subfamily D, member 3 /// olfactory receptor, family 5, subfamily V, member 1 OR12D3 /// OR5V1 81696 /// 81797 NM_030876 /// NM_030959 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208099_x_at NM_015072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015072.1 /DEF=Homo sapiens KIAA0998 protein (KIAA0998), mRNA. /FEA=mRNA /GEN=KIAA0998 /PROD=KIAA0998 protein /DB_XREF=gi:13562091 /FL=gb:NM_015072.1 NM_015072 tubulin tyrosine ligase-like family, member 5 TTLL5 23093 NM_015072 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 208100_x_at NM_030913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030913.1 /DEF=Homo sapiens semaphorin Y (SEMAY), mRNA. /FEA=mRNA /GEN=SEMAY /PROD=semaphorin Y /DB_XREF=gi:13569867 /FL=gb:NM_030913.1 NM_030913 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C SEMA6C 10500 NM_001178061 /// NM_001178062 /// NM_030913 /// XM_005244833 /// XM_005244835 /// XM_005244836 /// XM_005244837 /// XM_005244838 /// XM_006711120 /// XM_006711121 /// XM_006711122 /// XM_006711123 /// XM_006711124 /// XM_006711125 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 208101_s_at NM_030914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030914.1 /DEF=Homo sapiens hypothetical protein MGC2668 (MGC2668), mRNA. /FEA=mRNA /GEN=MGC2668 /PROD=hypothetical protein MGC2668 /DB_XREF=gi:13569869 /FL=gb:NM_030914.1 NM_030914 ubiquitin related modifier 1 URM1 81605 NM_001135947 /// NM_001265582 /// NM_030914 /// NR_049743 0002098 // tRNA wobble uridine modification // inferred from mutant phenotype /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032447 // protein urmylation // inferred from electronic annotation /// 0034227 // tRNA thio-modification // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016783 // sulfurtransferase activity // inferred from direct assay 208102_s_at NM_002779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002779.1 /DEF=Homo sapiens pleckstrin and Sec7 domain protein (PSD), mRNA. /FEA=mRNA /GEN=PSD /PROD=pleckstrin and Sec7 domain protein /DB_XREF=gi:4506160 /UG=Hs.154658 pleckstrin and Sec7 domain protein /FL=gb:NM_002779.1 NM_002779 pleckstrin and Sec7 domain containing PSD 5662 NM_001270965 /// NM_001270966 /// NM_002779 /// NR_073110 0007165 // signal transduction // non-traceable author statement /// 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0042995 // cell projection // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 208103_s_at NM_030920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030920.1 /DEF=Homo sapiens hypothetical protein MGC5350 (MGC5350), mRNA. /FEA=mRNA /GEN=MGC5350 /PROD=hypothetical protein MGC5350 /DB_XREF=gi:13569878 /FL=gb:NM_030920.1 NM_030920 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E ANP32E 81611 NM_001136478 /// NM_001136479 /// NM_001280559 /// NM_001280560 /// NM_030920 /// XM_005245513 /// XM_005245514 /// XR_426799 /// XR_426800 0016568 // chromatin modification // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0043486 // histone exchange // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0042393 // histone binding // inferred from direct assay 208104_s_at NM_030935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030935.1 /DEF=Homo sapiens TSC-22-like (THG-1), mRNA. /FEA=mRNA /GEN=THG-1 /PROD=TSC-22-like /DB_XREF=gi:13569900 /FL=gb:NM_030935.1 NM_030935 TSC22 domain family, member 4 TSC22D4 81628 NM_030935 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208105_at NM_000164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000164.1 /DEF=Homo sapiens gastric inhibitory polypeptide receptor (GIPR), mRNA. /FEA=mRNA /GEN=GIPR /PROD=gastric inhibitory polypeptide receptor /DB_XREF=gi:4503998 /UG=Hs.251412 gastric inhibitory polypeptide receptor /FL=gb:U39231.1 gb:NM_000164.1 NM_000164 gastric inhibitory polypeptide receptor GIPR 2696 NM_000164 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0038192 // gastric inhibitory peptide signaling pathway // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016519 // gastric inhibitory peptide receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation 208106_x_at NM_002782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002782.3 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 6 (PSG6), mRNA. /FEA=mRNA /GEN=PSG6 /PROD=pregnancy specific beta-1-glycoprotein 6 /DB_XREF=gi:7524013 /UG=Hs.252097 pregnancy specific beta-1-glycoprotein 6 /FL=gb:M33666.1 gb:NM_002782.3 NM_002782 pregnancy specific beta-1-glycoprotein 6 PSG6 5675 NM_001031850 /// NM_002782 0007565 // female pregnancy // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 208107_s_at NM_030941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030941.1 /DEF=Homo sapiens exonuclease NEF-sp (LOC81691), mRNA. /FEA=mRNA /GEN=LOC81691 /PROD=exonuclease NEF-sp /DB_XREF=gi:13569912 /FL=gb:NM_030941.1 NM_030941 exonuclease NEF-sp LOC81691 81691 NM_001144924 /// NM_001199053 /// NM_030941 /// XM_005255604 /// XM_005255606 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 208108_s_at AF030626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF030626.1 /DEF=Homo sapiens vasopressin V2 receptor mRNA, complete cds. /FEA=mRNA /PROD=vasopressin V2 receptor /DB_XREF=gi:2623239 /UG=Hs.2524 arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) /FL=gb:AF030626.1 gb:AF101727.1 gb:NM_000054.2 AF030626 arginine vasopressin receptor 2 AVPR2 554 NM_000054 /// NM_001146151 /// NR_027419 /// XM_006724828 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007599 // hemostasis // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208109_s_at NM_030944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030944.1 /DEF=Homo sapiens chromosome 15 open reading frame 5 (C15ORF5), mRNA. /FEA=mRNA /GEN=C15ORF5 /PROD=chromosome 15 open reading frame 5 /DB_XREF=gi:13569916 /FL=gb:NM_030944.1 NM_030944 long intergenic non-protein coding RNA 597 LINC00597 81698 NM_030944 /// NR_026813 208110_x_at NM_030973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030973.1 /DEF=Homo sapiens hypothetical protein TCBAP0758 (TCBAP0758), mRNA. /FEA=mRNA /GEN=TCBAP0758 /PROD=hypothetical protein TCBAP0758 /DB_XREF=gi:13569947 /FL=gb:NM_030973.1 NM_030973 mediator complex subunit 25 MED25 81857 NM_030973 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0035563 // positive regulation of chromatin binding // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 2001178 // positive regulation of mediator complex assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0046965 // retinoid X receptor binding // inferred from physical interaction 208111_at NM_000054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000054.2 /DEF=Homo sapiens arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) (AVPR2), mRNA. /FEA=mRNA /GEN=AVPR2 /PROD=arginine vasopressin receptor 2 /DB_XREF=gi:4895106 /UG=Hs.2524 arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) /FL=gb:AF030626.1 gb:AF101727.1 gb:NM_000054.2 NM_000054 arginine vasopressin receptor 2 AVPR2 554 NM_000054 /// NM_001146151 /// NR_027419 /// XM_006724828 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007599 // hemostasis // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208112_x_at NM_006795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006795.1 /DEF=Homo sapiens EH domain containing 1 (EHD1), mRNA. /FEA=mRNA /GEN=EHD1 /PROD=EH domain containing 1 /DB_XREF=gi:5803008 /UG=Hs.155119 EH domain containing 1 /FL=gb:AF099011.1 gb:NM_006795.1 NM_006795 EH-domain containing 1 EHD1 10938 NM_001282444 /// NM_001282445 /// NM_006795 /// XM_006718424 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0016197 // endosomal transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from physical interaction /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208113_x_at NM_030979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030979.1 /DEF=Homo sapiens testis-specific poly(A)-binding protein (PABP) (LOC81874), mRNA. /FEA=mRNA /GEN=LOC81874 /PROD=testis-specific poly(A)-binding protein (PABP) /DB_XREF=gi:13569957 /FL=gb:NM_030979.1 NM_030979 poly(A) binding protein, cytoplasmic 3 PABPC3 5042 NM_030979 0016071 // mRNA metabolic process // non-traceable author statement 0005737 // cytoplasm // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay 208114_s_at NM_030980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030980.1 /DEF=Homo sapiens hypothetical protein FLJ12671 (FLJ12671), mRNA. /FEA=mRNA /GEN=FLJ12671 /PROD=hypothetical protein FLJ12671 /DB_XREF=gi:13569959 /FL=gb:NM_030980.1 NM_030980 interferon stimulated exonuclease gene 20kDa-like 2 ISG20L2 81875 NM_030980 /// XM_005245516 /// XM_005245517 /// XM_005245518 /// XM_006711560 /// XM_006711561 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208115_x_at NM_030897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030897.1 /DEF=Homo sapiens hypothetical protein FLJ21617 (FLJ21617), mRNA. /FEA=mRNA /GEN=FLJ21617 /PROD=hypothetical protein FLJ21617 /DB_XREF=gi:13591869 /FL=gb:NM_030897.1 NM_030897 erythroid differentiation regulatory factor 1 EDRF1 26098 NM_001202438 /// NM_015608 /// NM_030897 /// NR_110857 /// NR_110858 /// NR_110859 /// XM_005269687 /// XM_005269688 /// XM_005269689 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 208116_s_at NM_005907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005907.1 /DEF=Homo sapiens mannosidase, alpha, class 1A, member 1 (MAN1A1), mRNA. /FEA=mRNA /GEN=MAN1A1 /PROD=mannosidase, alpha, class 1A, member 1 /DB_XREF=gi:5174520 /UG=Hs.25253 mannosidase, alpha, class 1A, member 1 /FL=gb:NM_005907.1 NM_005907 mannosidase, alpha, class 1A, member 1 MAN1A1 4121 NM_005907 /// XM_005266986 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 208117_s_at NM_031206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031206.1 /DEF=Homo sapiens hypothetical protein FLJ12525 (FLJ12525), mRNA. /FEA=mRNA /GEN=FLJ12525 /PROD=hypothetical protein FLJ12525 /DB_XREF=gi:13654269 /FL=gb:NM_031206.1 NM_031206 LAS1-like (S. cerevisiae) LAS1L 81887 NM_001170649 /// NM_001170650 /// NM_031206 /// XM_005262301 /// XM_005262303 /// XM_005262304 /// XM_005262305 /// XM_005262306 /// XM_005262307 /// XR_244504 /// XR_430522 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208118_x_at NM_031211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031211.1 /DEF=Homo sapiens LAT1-3TM protein (LAT1-3TM), mRNA. /FEA=mRNA /GEN=LAT1-3TM /PROD=LAT1-3TM protein /DB_XREF=gi:13654279 /FL=gb:NM_031211.1 NM_031211 putative L-type amino acid transporter 1-like protein IMAA-like /// solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1 /// solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2 /// SMG1 pseudogene 3 LOC101060604 /// SLC7A5P1 /// SLC7A5P2 /// SMG1P3 81893 /// 387254 /// 100271836 /// 101060604 NM_031211 /// NR_002593 /// NR_002594 /// NR_027155 /// XM_005276494 /// XM_006726608 /// XM_006726609 0003333 // amino acid transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation 208119_s_at NM_031218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031218.1 /DEF=Homo sapiens hypothetical protein FLJ12488 (FLJ12488), mRNA. /FEA=mRNA /GEN=FLJ12488 /PROD=hypothetical protein FLJ12488 /DB_XREF=gi:13654291 /FL=gb:NM_031218.1 NM_031218 zinc finger protein 93 ZNF93 81931 NM_001004126 /// NM_031218 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208120_x_at NM_031221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031221.1 /DEF=Homo sapiens hypothetical protein FKSG63 (FKSG63), mRNA. /FEA=mRNA /GEN=FKSG63 /PROD=hypothetical protein FKSG63 /DB_XREF=gi:13654297 /FL=gb:NM_031221.1 NM_031221 FKSG49 FKSG49 400949 XR_041698 208121_s_at NM_002848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002848.2 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 2, mRNA. /FEA=mRNA /GEN=PTPRO /PROD=receptor-type protein tyrosine phosphatase O,isoform b precursor /DB_XREF=gi:13677212 /FL=gb:NM_002848.2 NM_002848 protein tyrosine phosphatase, receptor type, O PTPRO 5800 NM_002848 /// NM_030667 /// NM_030668 /// NM_030669 /// NM_030670 /// NM_030671 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0002548 // monocyte chemotaxis // inferred from mutant phenotype /// 0003093 // regulation of glomerular filtration // inferred from sequence or structural similarity /// 0003105 // negative regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036060 // slit diaphragm assembly // inferred from sequence or structural similarity /// 0036060 // slit diaphragm assembly // non-traceable author statement /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090260 // negative regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 208122_x_at NM_012313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012313.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 (KIR2DS3), mRNA. /FEA=mRNA /GEN=KIR2DS3 /PROD=killer cell immunoglobulin-like receptor, twodomains, short cytoplasmic tail, 3 /DB_XREF=gi:6912473 /UG=Hs.258572 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 /FL=gb:L76670.1 gb:AF022047.1 gb:NM_012313.1 NM_012313 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 KIR2DS3 3808 NM_012313 /// XM_006725434 /// XM_006725660 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030110 // HLA-C specific inhibitory MHC class I receptor activity // non-traceable author statement 208123_at AF338730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF338730.1 /DEF=Homo sapiens potassium voltage-gated channel, Shab-related subfamily, member 2 (KCNB2), mRNA, complete cds. /FEA=mRNA /GEN=KCNB2 /PROD=potassium voltage-gated channel, Shab-relatedsubfamily, member 2 /DB_XREF=gi:13242171 /UG=Hs.121498 potassium voltage-gated channel, Shab-related subfamily, member 2 /FL=gb:AF338730.1 gb:U69962.1 gb:NM_004770.1 AF338730 potassium voltage-gated channel, Shab-related subfamily, member 2 KCNB2 9312 NM_004770 /// XM_006716483 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208124_s_at NM_004263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004263.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F (SEMA4F), mRNA. /FEA=mRNA /GEN=SEMA4F /PROD=semaphorin W /DB_XREF=gi:4759093 /UG=Hs.25887 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F /FL=gb:AB022317.1 gb:NM_004263.1 NM_004263 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F SEMA4F 10505 NM_001271661 /// NM_001271662 /// NM_004263 /// NR_073398 /// NR_073399 /// XM_006711919 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208126_s_at NM_000772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000772.1 /DEF=Homo sapiens cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18 (CYP2C18), mRNA. /FEA=mRNA /GEN=CYP2C18 /PROD=cytochrome P450, subfamily IIC (mephenytoin4-hydroxylase), polypeptide 18 /DB_XREF=gi:13699815 /FL=gb:NM_000772.1 NM_000772 cytochrome P450, family 2, subfamily C, polypeptide 18 CYP2C18 1562 NM_000772 /// NM_001128925 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 208127_s_at NM_014011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014011.1 /DEF=Homo sapiens KIAA0671 gene product (KIAA0671), mRNA. /FEA=mRNA /GEN=KIAA0671 /PROD=KIAA0671 gene product /DB_XREF=gi:7662239 /UG=Hs.169836 KIAA0671 gene product /FL=gb:AF073958.1 gb:NM_014011.1 NM_014011 suppressor of cytokine signaling 5 SOCS5 9655 NM_014011 /// NM_144949 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 208128_x_at NM_030615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030615.1 /DEF=Homo sapiens kinesin-like 3 (KNSL3), transcript variant 1, mRNA. /FEA=mRNA /GEN=KNSL3 /PROD=kinesin-like 3 isoform 1 /DB_XREF=gi:13699825 /FL=gb:NM_030615.1 NM_030615 kinesin family member 25 KIF25 3834 NM_005355 /// NM_030615 /// XM_006715473 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 208129_x_at NM_001754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001754.1 /DEF=Homo sapiens runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) (RUNX1), mRNA. /FEA=mRNA /GEN=RUNX1 /PROD=runt-related transcription factor 1 (acutemyeloid leukemia 1; aml1 oncogene) /DB_XREF=gi:4502592 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:NM_001754.1 NM_001754 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 208130_s_at NM_030984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030984.1 /DEF=Homo sapiens thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V) (TBXAS1), transcript variant TXS-II, mRNA. /FEA=mRNA /GEN=TBXAS1 /PROD=thromboxane A synthase 1 (platelet, cytochromeP450, subfamily V), isoform TXS-II /DB_XREF=gi:13699839 /FL=gb:NM_030984.1 NM_030984 thromboxane A synthase 1 (platelet) TBXAS1 6916 NM_001061 /// NM_001130966 /// NM_001166253 /// NM_001166254 /// NM_030984 /// NR_029394 0001516 // prostaglandin biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004796 // thromboxane-A synthase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208131_s_at NM_000961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000961.1 /DEF=Homo sapiens prostaglandin I2 (prostacyclin) synthase (PTGIS), mRNA. /FEA=mRNA /GEN=PTGIS /PROD=prostaglandin I2 (prostacyclin) synthase /DB_XREF=gi:13699858 /FL=gb:NM_000961.1 NM_000961 prostaglandin I2 (prostacyclin) synthase PTGIS 5740 NM_000961 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008116 // prostaglandin-I synthase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208132_x_at NM_004638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004638.1 /DEF=Homo sapiens HLA-B associated transcript-2 (D6S51E), mRNA. /FEA=mRNA /GEN=D6S51E /PROD=HLA-B associated transcript-2 /DB_XREF=gi:4758107 /UG=Hs.25911 HLA-B associated transcript-2 /FL=gb:M33509.1 gb:NM_004638.1 NM_004638 proline-rich coiled-coil 2A PRRC2A 7916 NM_004638 /// NM_080686 /// XM_006715191 /// XM_006725507 /// XM_006725508 /// XM_006725723 /// XM_006725724 /// XM_006725833 /// XM_006725834 /// XM_006725922 /// XM_006726023 /// XM_006726024 /// XM_006726111 /// XM_006726112 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208133_at NM_006081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006081.1 /DEF=Homo sapiens MHC binding factor, beta (MHCBFB), mRNA. /FEA=mRNA /GEN=MHCBFB /PROD=MHC binding factor, beta /DB_XREF=gi:5174562 /UG=Hs.2654 MHC binding factor, beta /FL=gb:NM_006081.1 NM_006081 208134_x_at NM_031246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031246.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 2 (PSG2), mRNA. /FEA=mRNA /GEN=PSG2 /PROD=pregnancy specific beta-1-glycoprotein 2 /DB_XREF=gi:13702710 /FL=gb:NM_031246.1 NM_031246 pregnancy specific beta-1-glycoprotein 2 PSG2 5670 NM_031246 0007565 // female pregnancy // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 208135_at NM_006481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006481.1 /DEF=Homo sapiens transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor (TCF2), transcript variant b, mRNA. /FEA=mRNA /GEN=TCF2 /PROD=transcription factor 2, isoform b /DB_XREF=gi:6031204 /UG=Hs.169853 transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor /FL=gb:NM_006481.1 NM_006481 HNF1 homeobox B HNF1B 6928 NM_000458 /// NM_001165923 /// NM_006481 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001714 // endodermal cell fate specification // inferred from electronic annotation /// 0001822 // kidney development // inferred from direct assay /// 0001822 // kidney development // inferred from mutant phenotype /// 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0035565 // regulation of pronephros size // inferred from mutant phenotype /// 0039020 // pronephric nephron tubule development // inferred from genetic interaction /// 0042663 // regulation of endodermal cell fate specification // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048793 // pronephros development // inferred from mutant phenotype /// 0048806 // genitalia development // inferred from mutant phenotype /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060429 // epithelium development // inferred from electronic annotation /// 0060677 // ureteric bud elongation // inferred from electronic annotation /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061017 // hepatoblast differentiation // inferred from electronic annotation /// 0061296 // negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis // inferred from electronic annotation /// 0072095 // regulation of branch elongation involved in ureteric bud branching // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072176 // nephric duct development // inferred from electronic annotation /// 0072177 // mesonephric duct development // inferred from electronic annotation /// 0072179 // nephric duct formation // inferred from electronic annotation /// 0072181 // mesonephric duct formation // inferred from electronic annotation /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208136_s_at NM_030970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030970.1 /DEF=Homo sapiens hypothetical protein MGC3771 (MGC3771), mRNA. /FEA=mRNA /GEN=MGC3771 /PROD=hypothetical protein MGC3771 /DB_XREF=gi:13775163 /FL=gb:NM_030970.1 NM_030970 ZNF205 antisense RNA 1 ZNF205-AS1 81854 NR_024166 /// NR_024167 208137_x_at NM_030972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030972.1 /DEF=Homo sapiens hypothetical protein MGC5384 (MGC5384), mRNA. /FEA=mRNA /GEN=MGC5384 /PROD=hypothetical protein MGC5384 /DB_XREF=gi:13775165 /FL=gb:NM_030972.1 NM_030972 zinc finger protein 611 ZNF611 81856 NM_001161499 /// NM_001161500 /// NM_001161501 /// NM_030972 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 208138_at NM_000805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000805.2 /DEF=Homo sapiens gastrin (GAS), mRNA. /FEA=mRNA /GEN=GAS /PROD=gastrin precursor /DB_XREF=gi:6005999 /UG=Hs.2681 gastrin /FL=gb:NM_000805.2 NM_000805 gastrin GAST 2520 NM_000805 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208139_s_at NM_031269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031269.1 /DEF=Homo sapiens PRO1386 protein (PRO1386), mRNA. /FEA=mRNA /GEN=PRO1386 /PROD=PRO1386 protein /DB_XREF=gi:13775169 /FL=gb:NM_031269.1 NM_031269 208140_s_at NM_031294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031294.1 /DEF=Homo sapiens hypothetical protein DKFZp586M1120 (DKFZP586M1120), mRNA. /FEA=mRNA /GEN=DKFZP586M1120 /PROD=hypothetical protein DKFZp586M1120 /DB_XREF=gi:13775213 /FL=gb:NM_031294.1 NM_031294 leucine rich repeat containing 48 LRRC48 83450 NM_001130090 /// NM_001130091 /// NM_001130092 /// NM_031294 /// XM_005256810 /// XM_006721583 /// XM_006721584 /// XM_006721585 0005737 // cytoplasm // inferred from direct assay 208141_s_at NM_031304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031304.1 /DEF=Homo sapiens hypothetical protein MGC4293 (MGC4293), mRNA. /FEA=mRNA /GEN=MGC4293 /PROD=hypothetical protein MGC4293 /DB_XREF=gi:13775227 /FL=gb:NM_031304.1 NM_031304 deoxyhypusine hydroxylase/monooxygenase DOHH 83475 NM_001145165 /// NM_031304 0008612 // peptidyl-lysine modification to peptidyl-hypusine // inferred from mutant phenotype /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019135 // deoxyhypusine monooxygenase activity // inferred from mutant phenotype /// 0019135 // deoxyhypusine monooxygenase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208142_at NM_006683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006683.2 /DEF=Homo sapiens human epididymis-specific 3 alpha (HE3-ALPHA), mRNA. /FEA=mRNA /GEN=HE3-ALPHA /PROD=human epididymis-specific 3 alpha /DB_XREF=gi:11386188 /UG=Hs.2718 human epididymis-specific 3 alpha /FL=gb:NM_006683.2 NM_006683 epididymal protein 3A EDDM3A 10876 NM_006683 0007321 // sperm displacement // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 208143_s_at NM_006683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006683.2 /DEF=Homo sapiens human epididymis-specific 3 alpha (HE3-ALPHA), mRNA. /FEA=mRNA /GEN=HE3-ALPHA /PROD=human epididymis-specific 3 alpha /DB_XREF=gi:11386188 /UG=Hs.2718 human epididymis-specific 3 alpha /FL=gb:NM_006683.2 NM_006683 epididymal protein 3A EDDM3A 10876 NM_006683 0007321 // sperm displacement // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 208144_s_at NM_031245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031245.1 /DEF=Homo sapiens hypothetical protein PP1345 (PP1345), mRNA. /FEA=mRNA /GEN=PP1345 /PROD=hypothetical protein PP1345 /DB_XREF=gi:13786118 /FL=gb:NM_031245.1 NM_031245 208145_at NM_017959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017959.1 /DEF=Homo sapiens hypothetical protein FLJ20802 (FLJ20802), mRNA. /FEA=mRNA /GEN=FLJ20802 /PROD=hypothetical protein FLJ20802 /DB_XREF=gi:8923681 /UG=Hs.272200 hypothetical protein FLJ20802 /FL=gb:NM_017959.1 NM_017959 208146_s_at NM_031311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031311.1 /DEF=Homo sapiens serine carboxypeptidase vitellogenic-like (LOC54504), mRNA. /FEA=mRNA /GEN=LOC54504 /PROD=serine carboxypeptidase vitellogenic-like /DB_XREF=gi:13786124 /FL=gb:NM_031311.1 NM_031311 carboxypeptidase, vitellogenic-like CPVL 54504 NM_019029 /// NM_031311 /// XM_005249786 0006508 // proteolysis // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 208147_s_at NM_030878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030878.1 /DEF=Homo sapiens cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 (CYP2C8), transcript variant Hp1-2, mRNA. /FEA=mRNA /GEN=CYP2C8 /PROD=cytochrome P450, subfamily IIC, polypeptide 8,isoform 2 /DB_XREF=gi:13787186 /FL=gb:NM_030878.1 NM_030878 cytochrome P450, family 2, subfamily C, polypeptide 8 CYP2C8 1558 NM_000770 /// NM_001198853 /// NM_001198854 /// NM_001198855 /// NM_030878 0006082 // organic acid metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 208148_at NM_017533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017533.1 /DEF=Homo sapiens myosin, heavy polypeptide 4, skeletal muscle (MYH4), mRNA. /FEA=mRNA /GEN=MYH4 /PROD=myosin, heavy polypeptide 4, skeletal muscle /DB_XREF=gi:11024711 /UG=Hs.272207 myosin, heavy polypeptide 4, skeletal muscle /FL=gb:NM_017533.1 gb:AF111783.2 NM_017533 myosin, heavy chain 4, skeletal muscle MYH4 4622 NM_017533 /// XM_005256650 0006200 // ATP catabolic process // non-traceable author statement /// 0006936 // muscle contraction // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030049 // muscle filament sliding // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005859 // muscle myosin complex // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from direct assay /// 0030017 // sarcomere // non-traceable author statement /// 0032982 // myosin filament // inferred from electronic annotation 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement 208149_x_at NM_030653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030653.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 (S.cerevisiae CHL1-like helicase) (DDX11), transcript variant 1, mRNA. /FEA=mRNA /GEN=DDX11 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 /DB_XREF=gi:13787196 /FL=gb:NM_030653.1 NM_030653 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 DDX11 1663 NM_001257144 /// NM_001257145 /// NM_004399 /// NM_030653 /// NM_030655 /// NM_152438 /// XM_005253331 /// XM_005253333 /// XM_006719041 /// XM_006719042 /// XM_006719043 /// XM_006719044 /// XM_006719045 /// XM_006719046 /// XM_006719047 /// XM_006719048 /// XM_006719049 /// XM_006719050 /// XM_006719051 /// XM_006719052 /// XM_006719053 /// XR_429031 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000084 // mitotic S phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 208151_x_at NM_030881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030881.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 17 (72kD) (DDX17), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDX17 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 17,isoform 2 /DB_XREF=gi:13787203 /FL=gb:NM_030881.1 NM_030881 DEAD (Asp-Glu-Ala-Asp) box helicase 17 DDX17 10521 NM_001098504 /// NM_001098505 /// NM_006386 /// NM_030881 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208152_s_at NM_004728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004728.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 21 (DDX21), mRNA. /FEA=mRNA /GEN=DDX21 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 21 /DB_XREF=gi:13787208 /FL=gb:NM_004728.1 NM_004728 DEAD (Asp-Glu-Ala-Asp) box helicase 21 DDX21 9188 NM_001256910 /// NM_004728 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208153_s_at NM_001447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001447.1 /DEF=Homo sapiens FAT tumor suppressor (Drosophila) homolog 2 (FAT2), mRNA. /FEA=mRNA /GEN=FAT2 /PROD=FAT tumor suppressor 2 precursor /DB_XREF=gi:13787216 /FL=gb:NM_001447.1 NM_001447 FAT atypical cadherin 2 FAT2 2196 NM_001447 /// XM_006714761 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0010631 // epithelial cell migration // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208154_at NM_016646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016646.1 /DEF=Homo sapiens mesenchymal stem cell protein DSCD28 (LOC51336), mRNA. /FEA=mRNA /GEN=LOC51336 /PROD=mesenchymal stem cell protein DSCD28 /DB_XREF=gi:7706197 /UG=Hs.272416 mesenchymal stem cell protein DSCD28 /FL=gb:AF242772.1 gb:NM_016646.1 NM_016646 208155_x_at NM_001476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001476.1 /DEF=Homo sapiens G antigen 6 (GAGE6), mRNA. /FEA=mRNA /GEN=GAGE6 /PROD=G antigen 6 /DB_XREF=gi:4503886 /UG=Hs.272484 G antigen 6 /FL=gb:NM_001476.1 gb:U19147.1 NM_001476 G antigen 1 /// G antigen 12B /// G antigen 12C /// G antigen 12D /// G antigen 12E /// G antigen 12F /// G antigen 12G /// G antigen 12H /// G antigen 12I /// G antigen 12J /// G antigen 13 /// G antigen 2D /// G antigen 4 /// G antigen 5 /// G antigen 6 /// G antigen 7 GAGE1 /// GAGE12B /// GAGE12C /// GAGE12D /// GAGE12E /// GAGE12F /// GAGE12G /// GAGE12H /// GAGE12I /// GAGE12J /// GAGE13 /// GAGE2D /// GAGE4 /// GAGE5 /// GAGE6 /// GAGE7 2543 /// 2576 /// 2577 /// 2578 /// 2579 /// 26748 /// 645051 /// 645073 /// 729396 /// 729408 /// 729422 /// 729428 /// 729431 /// 729442 /// 100008586 /// 100132399 NM_001040663 /// NM_001098405 /// NM_001098406 /// NM_001098407 /// NM_001098408 /// NM_001098409 /// NM_001098410 /// NM_001098412 /// NM_001098418 /// NM_001127199 /// NM_001127345 /// NM_001468 /// NM_001474 /// NM_001475 /// NM_001476 /// NM_001477 /// NM_021123 /// NR_102272 /// XM_005272739 /// XM_005278009 0006968 // cellular defense response // traceable author statement 0005515 // protein binding // inferred from physical interaction 208156_x_at NM_031308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031308.1 /DEF=Homo sapiens epiplakin 1 (EPPK1), mRNA. /FEA=mRNA /GEN=EPPK1 /PROD=epiplakin 1 /DB_XREF=gi:13876385 /FL=gb:NM_031308.1 NM_031308 epiplakin 1 EPPK1 83481 NM_031308 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 208157_at NM_009586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_009586.1 /DEF=Homo sapiens single-minded (Drosophila) homolog 2 (SIM2), transcript variant SIM2s, mRNA. /FEA=mRNA /GEN=SIM2 /PROD=single-minded (Drosophila) homolog 2 shortisoform /DB_XREF=gi:7108361 /UG=Hs.27311 single-minded (Drosophila) homolog 2 /FL=gb:U80457.1 gb:NM_009586.1 NM_009586 single-minded family bHLH transcription factor 2 SIM2 6493 NM_005069 /// NM_009586 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 208158_s_at NM_018030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018030.1 /DEF=Homo sapiens oxysterol-binding protein-related protein 1 (FLJ10217), mRNA. /FEA=mRNA /GEN=FLJ10217 /PROD=oxysterol-binding protein-related protein 1 /DB_XREF=gi:13877169 /FL=gb:NM_018030.1 NM_018030 oxysterol binding protein-like 1A OSBPL1A 114876 NM_001242508 /// NM_018030 /// NM_080597 /// NM_133268 /// XM_006722380 /// XM_006722381 /// XM_006722382 /// XM_006722383 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 208159_x_at NM_004399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004399.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 (S.cerevisiae CHL1-like helicase) (DDX11), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDX11 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 /DB_XREF=gi:4758135 /UG=Hs.27424 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 (S.cerevisiae CHL1-like helicase) /FL=gb:NM_004399.1 NM_004399 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 DDX11 1663 NM_001257144 /// NM_001257145 /// NM_004399 /// NM_030653 /// NM_030655 /// NM_152438 /// XM_005253331 /// XM_005253333 /// XM_006719041 /// XM_006719042 /// XM_006719043 /// XM_006719044 /// XM_006719045 /// XM_006719046 /// XM_006719047 /// XM_006719048 /// XM_006719049 /// XM_006719050 /// XM_006719051 /// XM_006719052 /// XM_006719053 /// XR_429031 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000084 // mitotic S phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 208160_at NM_018033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_018033.1 /DEF=Homo sapiens hypothetical protein FLJ10232 (FLJ10232), mRNA. /FEA=mRNA /GEN=FLJ10232 /PROD=hypothetical protein FLJ10232 /DB_XREF=gi:8922298 /UG=Hs.274272 hypothetical protein FLJ10232 /FL=gb:NM_018033.1 NM_018033 208161_s_at NM_020037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020037.1 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 3 (ABCC3), transcript variant MRP3A, mRNA. /FEA=mRNA /GEN=ABCC3 /PROD=ATP-binding cassette, sub-family C, member 3,isoform MRP3A /DB_XREF=gi:9955971 /UG=Hs.90786 ATP-binding cassette, sub-family C (CFTRMRP), member 3 /FL=gb:AF085691.1 gb:NM_020037.1 NM_020037 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 ABCC3 8714 NM_001144070 /// NM_003786 /// NM_020037 /// NM_020038 /// XM_005257763 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208162_s_at NM_018033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018033.1 /DEF=Homo sapiens hypothetical protein FLJ10232 (FLJ10232), mRNA. /FEA=mRNA /GEN=FLJ10232 /PROD=hypothetical protein FLJ10232 /DB_XREF=gi:8922298 /UG=Hs.274272 hypothetical protein FLJ10232 /FL=gb:NM_018033.1 NM_018033 208163_s_at NM_017731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017731.1 /DEF=Homo sapiens hypothetical protein FLJ20260 (FLJ20260), mRNA. /FEA=mRNA /GEN=FLJ20260 /PROD=hypothetical protein FLJ20260 /DB_XREF=gi:8923235 /UG=Hs.274370 hypothetical protein FLJ20260 /FL=gb:NM_017731.1 NM_017731 oxysterol binding protein-like 7 OSBPL7 114881 NM_017731 /// NM_145798 /// XM_005257010 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 1901800 // positive regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 208164_s_at NM_002186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002186.1 /DEF=Homo sapiens interleukin 9 receptor (IL9R), mRNA. /FEA=mRNA /GEN=IL9R /PROD=interleukin 9 receptor /DB_XREF=gi:4504684 /UG=Hs.1702 interleukin 9 receptor /FL=gb:M84747.1 gb:NM_002186.1 NM_002186 interleukin 9 receptor IL9R 3581 NM_002186 /// NM_176786 /// XM_006724817 /// XM_006724880 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0038113 // interleukin-9-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004919 // interleukin-9 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019983 // interleukin-9 binding // inferred from electronic annotation 208165_s_at NM_005865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005865.1 /DEF=Homo sapiens protease, serine, 16 (thymus) (PRSS16), mRNA. /FEA=mRNA /GEN=PRSS16 /PROD=protease, serine, 16 (thymus) /DB_XREF=gi:5031992 /UG=Hs.274407 protease, serine, 16 (thymus) /FL=gb:AF052514.1 gb:NM_005865.1 NM_005865 protease, serine, 16 (thymus) PRSS16 10279 NM_005865 0006508 // proteolysis // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 208166_at NM_022564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022564.1 /DEF=Homo sapiens matrix metalloproteinase 16 (membrane-inserted) (MMP16), transcript variant 2, mRNA. /FEA=mRNA /GEN=MMP16 /PROD=matrix metalloproteinase 16, isoform 2 /DB_XREF=gi:13027799 /UG=Hs.90800 matrix metalloproteinase 16 (membrane-inserted) /FL=gb:D83647.1 gb:NM_022564.1 NM_022564 matrix metallopeptidase 16 (membrane-inserted) MMP16 4325 NM_005941 /// NM_022564 /// NM_032297 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208167_s_at NM_022564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022564.1 /DEF=Homo sapiens matrix metalloproteinase 16 (membrane-inserted) (MMP16), transcript variant 2, mRNA. /FEA=mRNA /GEN=MMP16 /PROD=matrix metalloproteinase 16, isoform 2 /DB_XREF=gi:13027799 /UG=Hs.90800 matrix metalloproteinase 16 (membrane-inserted) /FL=gb:D83647.1 gb:NM_022564.1 NM_022564 matrix metallopeptidase 16 (membrane-inserted) MMP16 4325 NM_005941 /// NM_022564 /// NM_032297 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208168_s_at NM_003465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003465.1 /DEF=Homo sapiens chitinase 1 (chitotriosidase) (CHIT1), mRNA. /FEA=mRNA /GEN=CHIT1 /PROD=chitotriosidase /DB_XREF=gi:4502808 /UG=Hs.91093 chitinase 1 (chitotriosidase) /FL=gb:U29615.1 gb:NM_003465.1 NM_003465 chitinase 1 (chitotriosidase) CHIT1 1118 NM_001256125 /// NM_001270509 /// NM_003465 /// NR_045784 /// NR_045785 0000272 // polysaccharide catabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006030 // chitin metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from direct assay /// 0006032 // chitin catabolic process // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009617 // response to bacterium // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // traceable author statement /// 0008061 // chitin binding // traceable author statement /// 0008843 // endochitinase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 208169_s_at NM_000957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000957.1 /DEF=Homo sapiens prostaglandin E receptor 3 (subtype EP3) (PTGER3), mRNA. /FEA=mRNA /GEN=PTGER3 /PROD=prostaglandin E receptor 3 (subtype EP3) /DB_XREF=gi:4506256 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D86097.1 gb:NM_000957.1 NM_000957 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 208170_s_at NM_007028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007028.1 /DEF=Homo sapiens ring finger protein (RNF), mRNA. /FEA=mRNA /GEN=RNF /PROD=ring finger protein /DB_XREF=gi:5902055 /UG=Hs.91096 ring finger protein /FL=gb:NM_007028.1 NM_007028 tripartite motif containing 31 TRIM31 11074 NM_007028 /// NM_052816 /// XM_006714977 /// XM_006714978 /// XM_006725470 /// XM_006725685 /// XM_006725686 /// XM_006725687 /// XM_006725804 /// XM_006725805 /// XM_006725806 /// XM_006725894 /// XM_006725895 /// XM_006725983 /// XM_006725984 /// XM_006726074 /// XM_006726075 /// XR_427824 /// XR_430855 /// XR_430933 /// XR_430971 /// XR_430994 /// XR_430995 /// XR_431012 /// XR_431041 /// XR_431042 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208172_s_at NM_004770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004770.1 /DEF=Homo sapiens potassium voltage-gated channel, Shab-related subfamily, member 2 (KCNB2), mRNA. /FEA=mRNA /GEN=KCNB2 /PROD=potassium voltage-gated channel, Shab-relatedsubfamily, member 2 /DB_XREF=gi:4758621 /UG=Hs.121498 potassium voltage-gated channel, Shab-related subfamily, member 2 /FL=gb:AF338730.1 gb:U69962.1 gb:NM_004770.1 NM_004770 potassium voltage-gated channel, Shab-related subfamily, member 2 KCNB2 9312 NM_004770 /// XM_006716483 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208173_at NM_002176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002176.1 /DEF=Homo sapiens interferon, beta 1, fibroblast (IFNB1), mRNA. /FEA=mRNA /GEN=IFNB1 /PROD=interferon, beta 1, fibroblast /DB_XREF=gi:4504602 /UG=Hs.93177 interferon, beta 1, fibroblast /FL=gb:M25460.1 gb:M28622.1 gb:NM_002176.1 NM_002176 interferon, beta 1, fibroblast IFNB1 3456 NM_002176 0002250 // adaptive immune response // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // not recorded /// 0002312 // B cell activation involved in immune response // inferred from mutant phenotype /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // inferred from direct assay /// 0035458 // cellular response to interferon-beta // inferred from direct assay /// 0042100 // B cell proliferation // non-traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // non-traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // non-traceable author statement /// 0045581 // negative regulation of T cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // non-traceable author statement /// 0051607 // defense response to virus // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0071360 // cellular response to exogenous dsRNA // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000552 // negative regulation of T-helper 2 cell cytokine production // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred by curator /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0003714 // transcription corepressor activity // inferred from direct assay /// 0005125 // cytokine activity // not recorded /// 0005125 // cytokine activity // inferred from direct assay /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // non-traceable author statement 208174_x_at NM_005089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005089.1 /DEF=Homo sapiens U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2 (U2AF1RS2), mRNA. /FEA=mRNA /GEN=U2AF1RS2 /PROD=U2 small nuclear ribonucleoprotein auxiliaryfactor, small subunit-related protein 2 /DB_XREF=gi:4827045 /UG=Hs.171909 U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2 /FL=gb:D49677.1 gb:NM_005089.1 NM_005089 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 ZRSR2 8233 NM_005089 /// XM_005274597 /// XM_006724519 /// XM_006724520 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030628 // pre-mRNA 3'-splice site binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208175_s_at NM_004407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004407.1 /DEF=Homo sapiens dentin matrix acidic phosphoprotein (DMP1), mRNA. /FEA=mRNA /GEN=DMP1 /PROD=dentin matrix acidic phosphoprotein /DB_XREF=gi:4758171 /UG=Hs.93465 dentin matrix acidic phosphoprotein /FL=gb:U89012.1 gb:NM_004407.1 NM_004407 dentin matrix acidic phosphoprotein 1 DMP1 1758 NM_001079911 /// NM_004407 0001503 // ossification // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation 208176_at NM_012146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012146.1 /DEF=Homo sapiens double homeobox, 1 (DUX1), mRNA. /FEA=mRNA /GEN=DUX1 /PROD=double homeobox, 1 /DB_XREF=gi:11120735 /UG=Hs.274469 double homeobox, 1 /FL=gb:NM_012146.1 NM_012146 double homeobox 1 DUX1 26584 NM_012146 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208177_at NM_003052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003052.1 /DEF=Homo sapiens solute carrier family 34 (sodium phosphate), member 1 (SLC34A1), mRNA. /FEA=mRNA /GEN=SLC34A1 /PROD=solute carrier family 34 (sodium phosphate),member 1 /DB_XREF=gi:4506984 /UG=Hs.936 solute carrier family 34 (sodium phosphate), member 1 /FL=gb:L13258.1 gb:NM_003052.1 NM_003052 solute carrier family 34 (type II sodium/phosphate contransporter), member 1 SLC34A1 6569 NM_001167579 /// NM_003052 /// XM_005265974 /// XM_005265975 0001503 // ossification // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0035864 // response to potassium ion // inferred from electronic annotation /// 0042431 // indole metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from direct assay /// 0046689 // response to mercury ion // inferred from direct assay /// 0046849 // bone remodeling // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0071107 // response to parathyroid hormone // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from electronic annotation /// 0072734 // cellular response to staurosporine // inferred from electronic annotation /// 0097066 // response to thyroid hormone // inferred from electronic annotation /// 0097187 // dentinogenesis // inferred from electronic annotation /// 1901128 // gentamycin metabolic process // inferred from electronic annotation /// 1901652 // response to peptide // inferred from electronic annotation /// 1901684 // arsenate ion transmembrane transport // inferred from electronic annotation /// 2000120 // positive regulation of sodium-dependent phosphate transport // inferred from electronic annotation /// 2000187 // positive regulation of phosphate transmembrane transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // non-traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 208178_x_at NM_007118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007118.1 /DEF=Homo sapiens triple functional domain (PTPRF interacting) (TRIO), mRNA. /FEA=mRNA /GEN=TRIO /PROD=triple functional domain (PTPRF interacting) /DB_XREF=gi:6005921 /UG=Hs.171957 triple functional domain (PTPRF interacting) /FL=gb:U42390.1 gb:NM_007118.1 NM_007118 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 208179_x_at AF022048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022048.1 /DEF=Homo sapiens natural killer cell inhibitory receptor KIR2DL3 variant mRNA, complete cds. /FEA=mRNA /PROD=natural killer cell inhibitory receptor KIR2DL3variant /DB_XREF=gi:2760896 /UG=Hs.274484 NK-receptor /FL=gb:AF285439.1 gb:AF208054.1 gb:U73395.1 gb:AF022048.1 gb:NM_015868.1 AF022048 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 KIR2DL3 3804 NM_014511 /// NM_015868 /// XM_005277304 /// XM_006725426 /// XM_006725427 /// XM_006725435 /// XM_006725436 /// XM_006725669 /// XM_006726156 /// XM_006726157 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 208180_s_at NM_003543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003543.2 /DEF=Homo sapiens H4 histone family, member H (H4FH), mRNA. /FEA=mRNA /GEN=H4FH /PROD=H4 histone family, member H /DB_XREF=gi:5579466 /UG=Hs.93758 H4 histone family, member H /FL=gb:NM_003543.2 NM_003543 histone cluster 1, H4h HIST1H4H 8365 NM_003543 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208181_at NM_003543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003543.2 /DEF=Homo sapiens H4 histone family, member H (H4FH), mRNA. /FEA=mRNA /GEN=H4FH /PROD=H4 histone family, member H /DB_XREF=gi:5579466 /UG=Hs.93758 H4 histone family, member H /FL=gb:NM_003543.2 NM_003543 histone cluster 1, H4a /// histone cluster 1, H4b /// histone cluster 1, H4c /// histone cluster 1, H4d /// histone cluster 1, H4e /// histone cluster 1, H4f /// histone cluster 1, H4h /// histone cluster 1, H4i /// histone cluster 1, H4j /// histone cluster 1, H4k /// histone cluster 1, H4l /// histone cluster 2, H4a /// histone cluster 2, H4b /// histone cluster 4, H4 HIST1H4A /// HIST1H4B /// HIST1H4C /// HIST1H4D /// HIST1H4E /// HIST1H4F /// HIST1H4H /// HIST1H4I /// HIST1H4J /// HIST1H4K /// HIST1H4L /// HIST2H4A /// HIST2H4B /// HIST4H4 8294 /// 8359 /// 8360 /// 8361 /// 8362 /// 8363 /// 8364 /// 8365 /// 8366 /// 8367 /// 8368 /// 8370 /// 121504 /// 554313 NM_001034077 /// NM_003495 /// NM_003538 /// NM_003539 /// NM_003540 /// NM_003541 /// NM_003542 /// NM_003543 /// NM_003544 /// NM_003545 /// NM_003546 /// NM_003548 /// NM_021968 /// NM_175054 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208182_x_at NM_002172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002172.1 /DEF=Homo sapiens interferon, alpha 14 (IFNA14), mRNA. /FEA=mRNA /GEN=IFNA14 /PROD=interferon, alpha 14 /DB_XREF=gi:4504590 /UG=Hs.93907 interferon, alpha 14 /FL=gb:NM_002172.1 NM_002172 interferon, alpha 14 IFNA14 3448 NM_002172 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 208183_at NM_001059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001059.1 /DEF=Homo sapiens tachykinin receptor 3 (TACR3), mRNA. /FEA=mRNA /GEN=TACR3 /PROD=tachykinin receptor 3 /DB_XREF=gi:7669547 /UG=Hs.942 tachykinin receptor 3 /FL=gb:M89473.1 gb:NM_001059.1 NM_001059 tachykinin receptor 3 TACR3 6870 NM_001059 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208184_s_at NM_003274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003274.1 /DEF=Homo sapiens transmembrane protein 1 (TMEM1), mRNA. /FEA=mRNA /GEN=TMEM1 /PROD=transmembrane protein 1 /DB_XREF=gi:4507550 /UG=Hs.94479 transmembrane protein 1 /FL=gb:NM_003274.1 gb:U19252.1 NM_003274 trafficking protein particle complex subunit 10-like /// trafficking protein particle complex 10 LOC102724200 /// TRAPPC10 7109 /// 102724200 NM_001001723 /// NM_003274 /// XM_005261168 /// XM_005261169 /// XM_006723912 /// XM_006724046 /// XM_006724047 0006810 // transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015081 // sodium ion transmembrane transporter activity // traceable author statement 208185_x_at NM_016415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_016415.1 /DEF=Homo sapiens clone FLB3816 (LOC51216), mRNA. /FEA=mRNA /GEN=LOC51216 /PROD=clone FLB3816 /DB_XREF=gi:10047109 /UG=Hs.277887 clone FLB3816 /FL=gb:NM_016415.1 gb:AF113685.1 NM_016415 208186_s_at NM_005357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005357.1 /DEF=Homo sapiens lipase, hormone-sensitive (LIPE), mRNA. /FEA=mRNA /GEN=LIPE /PROD=lipase, hormone-sensitive /DB_XREF=gi:4885450 /UG=Hs.95351 lipase, hormone-sensitive /FL=gb:U40002.1 gb:NM_005357.1 NM_005357 lipase, hormone-sensitive LIPE 3991 NM_005357 /// XM_005258937 /// XM_005258938 /// XM_005258939 /// XM_005258940 /// XM_005258941 /// XM_006723218 0006468 // protein phosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from sequence or structural similarity /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0042758 // long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046340 // diacylglycerol catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016298 // lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033878 // hormone-sensitive lipase activity // inferred from electronic annotation 208187_s_at NM_016415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016415.1 /DEF=Homo sapiens clone FLB3816 (LOC51216), mRNA. /FEA=mRNA /GEN=LOC51216 /PROD=clone FLB3816 /DB_XREF=gi:10047109 /UG=Hs.277887 clone FLB3816 /FL=gb:NM_016415.1 gb:AF113685.1 NM_016415 208188_at NM_000226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000226.1 /DEF=Homo sapiens keratin 9 (epidermolytic palmoplantar keratoderma) (KRT9), mRNA. /FEA=mRNA /GEN=KRT9 /PROD=keratin 9 /DB_XREF=gi:4557704 /UG=Hs.2783 keratin 9 (epidermolytic palmoplantar keratoderma) /FL=gb:NM_000226.1 NM_000226 keratin 9 KRT9 3857 NM_000226 0007283 // spermatogenesis // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043588 // skin development // inferred from direct assay /// 0045109 // intermediate filament organization // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 208189_s_at NM_000260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000260.1 /DEF=Homo sapiens myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) (MYO7A), mRNA. /FEA=mRNA /GEN=MYO7A /PROD=myosin VIIA /DB_XREF=gi:4505306 /UG=Hs.95361 myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) /FL=gb:U39226.1 gb:NM_000260.1 NM_000260 myosin VIIA MYO7A 4647 NM_000260 /// NM_001127179 /// NM_001127180 /// XM_005274012 /// XM_006718558 /// XM_006718559 /// XM_006718560 /// XM_006718561 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007600 // sensory perception // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0042462 // eye photoreceptor cell development // inferred by curator /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0031477 // myosin VII complex // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from reviewed computational analysis /// 0051015 // actin filament binding // inferred from direct assay 208190_s_at NM_015925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015925.1 /DEF=Homo sapiens liver-specific bHLH-Zip transcription factor (LISCH7), mRNA. /FEA=mRNA /GEN=LISCH7 /PROD=LISCH protein /DB_XREF=gi:7706247 /UG=Hs.95697 liver-specific bHLH-Zip transcription factor /FL=gb:AF130366.1 gb:NM_015925.1 NM_015925 lipolysis stimulated lipoprotein receptor LSR 51599 NM_001260489 /// NM_001260490 /// NM_015925 /// NM_205834 /// NM_205835 /// XM_005258980 /// XM_005258982 0001889 // liver development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 208191_x_at NM_002780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002780.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 4 (PSG4), mRNA. /FEA=mRNA /GEN=PSG4 /PROD=pregnancy specific beta-1-glycoprotein 4 /DB_XREF=gi:4506170 /UG=Hs.278423 pregnancy specific beta-1-glycoprotein 4 /FL=gb:NM_002780.1 gb:U18469.1 NM_002780 pregnancy specific beta-1-glycoprotein 4 PSG4 5672 NM_001276495 /// NM_002780 /// NM_213633 /// XM_005259069 /// XM_005259073 0006952 // defense response // non-traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 208192_at NM_006679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006679.1 /DEF=Homo sapiens putative opioid receptor, neuromedin K (neurokinin B) receptor-like (TAC3RL), mRNA. /FEA=mRNA /GEN=TAC3RL /PROD=putative opioid receptor, neuromedin K(neurokinin B) receptor-like /DB_XREF=gi:5730076 /UG=Hs.957 putative opioid receptor, neuromedin K (neurokinin B) receptor-like /FL=gb:M84605.1 gb:NM_006679.1 NM_006679 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007217 // tachykinin receptor signaling pathway // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // traceable author statement 208193_at NM_000590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000590.1 /DEF=Homo sapiens interleukin 9 (IL9), mRNA. /FEA=mRNA /GEN=IL9 /PROD=interleukin 9 /DB_XREF=gi:10834979 /UG=Hs.960 interleukin 9 /FL=gb:NM_000590.1 gb:M30134.1 NM_000590 interleukin 9 IL9 3578 NM_000590 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0045407 // positive regulation of interleukin-5 biosynthetic process // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005140 // interleukin-9 receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 208194_s_at NM_005843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005843.1 /DEF=Homo sapiens STAM-like protein containing SH3 and ITAM domains 2 (STAM2), mRNA. /FEA=mRNA /GEN=STAM2 /PROD=STAM-like protein containing SH3 and ITAMdomains 2 /DB_XREF=gi:5032126 /UG=Hs.17200 STAM-like protein containing SH3 and ITAM domains 2 /FL=gb:AF042274.1 gb:NM_005843.1 NM_005843 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 STAM2 10254 NM_005843 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208195_at NM_003319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003319.1 /DEF=Homo sapiens titin (TTN), mRNA. /FEA=mRNA /GEN=TTN /PROD=titin /DB_XREF=gi:4507720 /UG=Hs.172004 titin /FL=gb:NM_003319.1 NM_003319 titin TTN 7273 NM_001256850 /// NM_001267550 /// NM_003319 /// NM_133378 /// NM_133379 /// NM_133432 /// NM_133437 /// XM_005246831 /// XM_006712723 /// XM_006712724 /// XM_006712725 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003300 // cardiac muscle hypertrophy // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006936 // muscle contraction // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006941 // striated muscle contraction // traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from expression pattern /// 0007512 // adult heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030240 // skeletal muscle thin filament assembly // inferred from mutant phenotype /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from mutant phenotype /// 0035995 // detection of muscle stretch // traceable author statement /// 0043056 // forward locomotion // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045859 // regulation of protein kinase activity // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype /// 0048769 // sarcomerogenesis // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from mutant phenotype /// 0051592 // response to calcium ion // inferred from direct assay /// 0055002 // striated muscle cell development // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005865 // striated muscle thin filament // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031430 // M band // inferred from direct assay /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0031674 // I band // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031433 // telethonin binding // inferred from physical interaction /// 0031433 // telethonin binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042805 // actinin binding // inferred from direct assay /// 0042805 // actinin binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay /// 0051371 // muscle alpha-actinin binding // inferred from physical interaction /// 0097493 // structural molecule activity conferring elasticity // traceable author statement 208196_x_at NM_006162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006162.1 /DEF=Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), mRNA. /FEA=mRNA /GEN=NFATC1 /PROD=nuclear factor of activated T-cells,cytoplasmic, calcineurin-dependent 1 /DB_XREF=gi:5453771 /UG=Hs.96149 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 /FL=gb:U59736.1 gb:NM_006162.1 NM_006162 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 4772 NM_001278669 /// NM_001278670 /// NM_001278672 /// NM_001278673 /// NM_001278675 /// NM_006162 /// NM_172387 /// NM_172388 /// NM_172389 /// NM_172390 /// XM_006722477 /// XM_006722478 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from sequence or structural similarity 208198_x_at NM_014512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014512.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 (KIR2DS1), mRNA. /FEA=mRNA /GEN=KIR2DS1 /PROD=killer cell immunoglobulin-like receptor, twodomains, short cytoplasmic tail, 1 /DB_XREF=gi:7657276 /UG=Hs.278455 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 /FL=gb:AF022045.1 gb:AF022046.1 gb:NM_014512.1 NM_014512 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 KIR2DS1 3806 NM_014512 /// XM_006725422 /// XM_006725423 /// XM_006725431 /// XM_006725432 /// XM_006725433 /// XM_006725439 /// XM_006725440 /// XM_006725642 /// XM_006725643 /// XM_006725657 /// XM_006725658 /// XM_006725659 /// XM_006725665 /// XM_006725666 /// XM_006725792 /// XM_006725793 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0030110 // HLA-C specific inhibitory MHC class I receptor activity // non-traceable author statement 208199_s_at NM_003409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003409.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp161 in mouse (ZFP161), mRNA. /FEA=mRNA /GEN=ZFP161 /PROD=zinc finger protein homologous to Zfp161 inmouse /DB_XREF=gi:4507958 /UG=Hs.156000 zinc finger protein homologous to Zfp161 in mouse /FL=gb:NM_003409.1 NM_003409 zinc finger and BTB domain containing 14 ZBTB14 7541 NM_001143823 /// NM_001243702 /// NM_001243704 /// NM_003409 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208200_at NM_000575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000575.1 /DEF=Homo sapiens interleukin 1, alpha (IL1A), mRNA. /FEA=mRNA /GEN=IL1A /PROD=interleukin 1, alpha /DB_XREF=gi:13236493 /UG=Hs.1722 interleukin 1, alpha /FL=gb:NM_000575.1 gb:M28983.1 NM_000575 interleukin 1, alpha IL1A 3552 NM_000575 0001660 // fever generation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0005125 // cytokine activity // inferred from mutant phenotype /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 208201_at NM_012147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012147.1 /DEF=Homo sapiens double homeobox, 2 (DUX2), mRNA. /FEA=mRNA /GEN=DUX2 /PROD=double homeobox, 2 /DB_XREF=gi:6912341 /UG=Hs.157425 double homeobox, 2 /FL=gb:AF068744.1 gb:NM_012147.1 NM_012147 D4Z4 binding element transcript (non-protein coding) /// double homeobox 3 /// double homeobox 4 /// double homeobox 4 like 1 /// double homeobox 4 like 2 /// double homeobox 4 like 24 /// double homeobox 4 like 3 /// double homeobox 4 like 4 /// double homeobox 4 like 5 /// double homeobox 4 like 6 /// double homeobox 4 like 7 /// double homeobox 4 like 8 /// double homeobox protein 4-like protein 4-like /// double homeobox protein 4-like protein 4-like /// double homeobox protein 4-like protein 2-like /// double homeobox protein 4-like /// double homeobox protein 4-like protein 4-like DBET /// DUX3 /// DUX4 /// DUX4L1 /// DUX4L2 /// DUX4L24 /// DUX4L3 /// DUX4L4 /// DUX4L5 /// DUX4L6 /// DUX4L7 /// DUX4L8 /// LOC100133400 /// LOC100287823 /// LOC100288289 /// LOC100291626 /// LOC652301 22947 /// 26582 /// 26583 /// 441056 /// 652301 /// 653543 /// 653544 /// 653545 /// 653548 /// 728410 /// 100133400 /// 100287823 /// 100288289 /// 100288687 /// 100291626 /// 100419743 /// 102723449 NM_001127386 /// NM_001127387 /// NM_001127388 /// NM_001127389 /// NM_001164467 /// NM_001177376 /// NM_001205218 /// NM_001278056 /// NM_001293798 /// NM_012147 /// NM_012148 /// NM_033178 /// NR_033487 /// NR_038191 /// NR_121644 /// XM_005274812 /// XM_005276047 /// XM_005276087 /// XM_006710226 /// XM_006710238 /// XM_006710245 /// XM_006718103 /// XM_006726416 /// XM_006726525 /// XR_426490 /// XR_431831 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0070317 // negative regulation of G0 to G1 transition // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208202_s_at NM_015288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015288.1 /DEF=Homo sapiens KIAA0239 protein (KIAA0239), mRNA. /FEA=mRNA /GEN=KIAA0239 /PROD=KIAA0239 protein /DB_XREF=gi:13375621 /UG=Hs.9729 KIAA0239 protein /FL=gb:BC004292.1 gb:NM_015288.1 NM_015288 jade family PHD finger 2 JADE2 23338 NM_001289984 /// NM_001289985 /// NM_015288 /// XM_005271942 /// XM_005271943 /// XM_005271944 /// XM_005271945 /// XM_005271946 /// XM_005271947 /// XM_005271948 /// XM_005271949 /// XM_005271950 /// XM_005271951 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208203_x_at NM_014513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014513.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 (KIR2DS5), mRNA. /FEA=mRNA /GEN=KIR2DS5 /PROD=killer cell immunoglobulin-like receptor, twodomains, short cytoplasmic tail, 5 /DB_XREF=gi:7657278 /UG=Hs.278456 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 /FL=gb:L76672.1 gb:NM_014513.1 NM_014513 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 KIR2DS5 3810 NM_014513 /// XM_006725424 /// XM_006725441 /// XM_006725648 /// XM_006725654 /// XM_006725787 /// XM_006725790 /// XM_006725794 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030110 // HLA-C specific inhibitory MHC class I receptor activity // non-traceable author statement 208204_s_at NM_001234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001234.2 /DEF=Homo sapiens caveolin 3 (CAV3), mRNA. /FEA=mRNA /GEN=CAV3 /PROD=caveolin 3 /DB_XREF=gi:4580416 /UG=Hs.98303 caveolin 3 /FL=gb:NM_001234.2 NM_001234 caveolin 3 CAV3 859 NM_001234 /// NM_033337 0001778 // plasma membrane repair // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007009 // plasma membrane organization // inferred from sequence or structural similarity /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007517 // muscle organ development // traceable author statement /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from mutant phenotype /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0014819 // regulation of skeletal muscle contraction // inferred from mutant phenotype /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016049 // cell growth // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0031116 // positive regulation of microtubule polymerization // inferred from sequence or structural similarity /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031579 // membrane raft organization // inferred from sequence or structural similarity /// 0033292 // T-tubule organization // traceable author statement /// 0038009 // regulation of signal transduction by receptor internalization // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0051394 // regulation of nerve growth factor receptor activity // inferred from mutant phenotype /// 0051647 // nucleus localization // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060299 // negative regulation of sarcomere organization // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from direct assay /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061052 // negative regulation of cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0070836 // caveola assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0090002 // establishment of protein localization to plasma membrane // inferred from electronic annotation /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 1900744 // regulation of p38MAPK cascade // inferred from electronic annotation /// 1900825 // regulation of membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from sequence or structural similarity /// 2000009 // negative regulation of protein localization to cell surface // non-traceable author statement /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // non-traceable author statement /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay /// 2001288 // positive regulation of caveolin-mediated endocytosis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0005246 // calcium channel regulator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0019870 // potassium channel inhibitor activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0071253 // connexin binding // inferred from direct assay 208205_at NM_014005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014005.1 /DEF=Homo sapiens protocadherin alpha 9 (PCDHA9), mRNA. /FEA=mRNA /GEN=PCDHA9 /PROD=protocadherin alpha 9 /DB_XREF=gi:7662067 /UG=Hs.98938 protocadherin alpha 9 /FL=gb:AB002343.1 gb:AF152487.1 gb:NM_014005.1 NM_014005 protocadherin alpha 9 PCDHA9 9752 NM_014005 /// NM_031857 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 208206_s_at NM_005825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005825.1 /DEF=Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), mRNA. /FEA=mRNA /GEN=RASGRP2 /PROD=RAS guanyl releasing protein 2 (calcium andDAG-regulated) /DB_XREF=gi:5031622 /UG=Hs.99491 RAS guanyl releasing protein 2 (calcium and DAG-regulated) /FL=gb:NM_005825.1 gb:AF043723.1 NM_005825 RAS guanyl releasing protein 2 (calcium and DAG-regulated) RASGRP2 10235 NM_001098670 /// NM_001098671 /// NM_005825 /// NM_153819 /// XM_005273707 /// XM_006718411 /// XM_006718412 /// XM_006718413 /// XM_006718414 /// XM_006718415 /// XM_006718416 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0008289 // lipid binding // traceable author statement /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208207_at NM_003163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003163.1 /DEF=Homo sapiens syntaxin 1B (STX1B), mRNA. /FEA=mRNA /GEN=STX1B /PROD=syntaxin 1B /DB_XREF=gi:4507290 /UG=Hs.99880 syntaxin 1B /FL=gb:NM_003163.1 gb:D37933.1 NM_003163 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // traceable author statement /// 0005234 // extracellular-glutamate-gated ion channel activity // traceable author statement /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation 208208_at NM_003802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003802.1 /DEF=Homo sapiens myosin, heavy polypeptide 13, skeletal muscle (MYH13), mRNA. /FEA=mRNA /GEN=MYH13 /PROD=myosin, heavy polypeptide 13, skeletal muscle /DB_XREF=gi:11321578 /UG=Hs.278488 myosin, heavy polypeptide 13, skeletal muscle /FL=gb:NM_003802.1 gb:AF111782.2 NM_003802 myosin, heavy chain 13, skeletal muscle MYH13 8735 NM_003802 0006936 // muscle contraction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000146 // microfilament motor activity // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 208209_s_at NM_000716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000716.1 /DEF=Homo sapiens complement component 4-binding protein, beta (C4BPB), mRNA. /FEA=mRNA /GEN=C4BPB /PROD=complement component 4-binding protein, beta /DB_XREF=gi:4502504 /UG=Hs.99886 complement component 4-binding protein, beta /FL=gb:L11244.1 gb:NM_000716.1 NM_000716 complement component 4 binding protein, beta C4BPB 725 NM_000716 /// NM_001017364 /// NM_001017365 /// NM_001017366 /// NM_001017367 /// XM_005273253 /// XM_005273254 /// XM_005273255 0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1903027 // regulation of opsonization // inferred by curator 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0044216 // other organism cell // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208210_at NM_002377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002377.2 /DEF=Homo sapiens MAS1 oncogene (MAS1), mRNA. /FEA=mRNA /GEN=MAS1 /PROD=MAS1 oncogene /DB_XREF=gi:6006022 /UG=Hs.99900 MAS1 oncogene /FL=gb:M13150.1 gb:NM_002377.2 NM_002377 MAS1 proto-oncogene, G protein-coupled receptor MAS1 4142 NM_002377 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014823 // response to activity // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from electronic annotation /// 0070528 // protein kinase C signaling // inferred from mutant phenotype /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001595 // angiotensin receptor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0004945 // angiotensin type II receptor activity // traceable author statement /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity 208211_s_at U66559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66559.1 /DEF=Human anaplastic lymphoma kinase receptor mRNA, complete cds. /FEA=mRNA /PROD=anaplastic lymphoma kinase receptor /DB_XREF=gi:1848243 /UG=Hs.278572 anaplastic lymphoma kinase (Ki-1) /FL=gb:U66559.1 gb:NM_004304.2 U66559 anaplastic lymphoma receptor tyrosine kinase ALK 238 NM_004304 0000187 // activation of MAPK activity // traceable author statement /// 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007018 // microtubule-based movement // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0035617 // stress granule disassembly // inferred from electronic annotation /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048666 // neuron development // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005871 // kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 208212_s_at NM_004304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004304.2 /DEF=Homo sapiens anaplastic lymphoma kinase (Ki-1) (ALK), mRNA. /FEA=mRNA /GEN=ALK /PROD=anaplastic lymphoma kinase Ki-1 /DB_XREF=gi:6715586 /UG=Hs.278572 anaplastic lymphoma kinase (Ki-1) /FL=gb:U66559.1 gb:NM_004304.2 NM_004304 anaplastic lymphoma receptor tyrosine kinase ALK 238 NM_004304 0000187 // activation of MAPK activity // traceable author statement /// 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0048666 // neuron development // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 208213_s_at NM_003471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003471.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), mRNA. /FEA=mRNA /GEN=KCNAB1 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, beta member 1 /DB_XREF=gi:4504822 /UG=Hs.172471 potassium voltage-gated channel, shaker-related subfamily, beta member 1 /FL=gb:NM_003471.1 NM_003471 potassium voltage-gated channel, shaker-related subfamily, beta member 1 KCNAB1 7881 NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 208214_at NM_000684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000684.1 /DEF=Homo sapiens adrenergic, beta-1-, receptor (ADRB1), mRNA. /FEA=mRNA /GEN=ADRB1 /PROD=beta-1-adrenergic receptor /DB_XREF=gi:4557264 /UG=Hs.99913 adrenergic, beta-1-, receptor /FL=gb:J03019.1 gb:NM_000684.1 NM_000684 adrenoceptor beta 1 ADRB1 153 NM_000684 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0002025 // vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0003061 // positive regulation of the force of heart contraction by norepinephrine // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0005980 // glycogen catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031649 // heat generation // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045823 // positive regulation of heart contraction // inferred from electronic annotation /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0046878 // positive regulation of saliva secretion // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation /// 0061051 // positive regulation of cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation /// 1900135 // positive regulation of renin secretion into blood stream // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004939 // beta-adrenergic receptor activity // traceable author statement /// 0004940 // beta1-adrenergic receptor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from direct assay /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031694 // alpha-2A adrenergic receptor binding // inferred from physical interaction /// 0035240 // dopamine binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051379 // epinephrine binding // inferred from electronic annotation /// 0051380 // norepinephrine binding // inferred from electronic annotation 208215_x_at NM_000797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000797.1 /DEF=Homo sapiens dopamine receptor D4 (DRD4), mRNA. /FEA=mRNA /GEN=DRD4 /PROD=dopamine receptor D4 /DB_XREF=gi:4503388 /UG=Hs.99922 dopamine receptor D4 /FL=gb:NM_000797.1 NM_000797 dopamine receptor D4 DRD4 1815 NM_000797 0000187 // activation of MAPK activity // inferred from direct assay /// 0001662 // behavioral fear response // non-traceable author statement /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007212 // dopamine receptor signaling pathway // inferred from direct assay /// 0007614 // short-term memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from sequence or structural similarity /// 0008355 // olfactory learning // inferred from electronic annotation /// 0009648 // photoperiodism // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from direct assay /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0034776 // response to histamine // inferred from direct assay /// 0035176 // social behavior // non-traceable author statement /// 0042053 // regulation of dopamine metabolic process // inferred from sequence or structural similarity /// 0042417 // dopamine metabolic process // inferred by curator /// 0042596 // fear response // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0050848 // regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from direct assay /// 0035240 // dopamine binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 208216_at NM_001934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001934.1 /DEF=Homo sapiens distal-less homeobox 4 (DLX4), mRNA. /FEA=mRNA /GEN=DLX4 /PROD=distal-less homeobox 4 /DB_XREF=gi:4503342 /UG=Hs.172648 distal-less homeobox 4 /FL=gb:U73328.1 gb:NM_001934.1 NM_001934 distal-less homeobox 4 DLX4 1748 NM_001934 /// NM_138281 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 208217_at NM_002043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002043.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) receptor, rho 2 (GABRR2), mRNA. /FEA=mRNA /GEN=GABRR2 /PROD=gamma-aminobutyric acid (GABA) receptor, rho 2precursor /DB_XREF=gi:4503870 /UG=Hs.99927 gamma-aminobutyric acid (GABA) receptor, rho 2 /FL=gb:M86868.1 gb:NM_002043.1 NM_002043 gamma-aminobutyric acid (GABA) A receptor, rho 2 GABRR2 2570 NM_002043 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 208218_s_at NM_020328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020328.1 /DEF=Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 3, mRNA. /FEA=mRNA /GEN=ACVR1B /PROD=activin A type IB receptor, isoform c precursor /DB_XREF=gi:10862693 /UG=Hs.99954 activin A receptor, type IB /FL=gb:NM_020328.1 gb:L10126.1 NM_020328 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 208219_at NM_020328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020328.1 /DEF=Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 3, mRNA. /FEA=mRNA /GEN=ACVR1B /PROD=activin A type IB receptor, isoform c precursor /DB_XREF=gi:10862693 /UG=Hs.99954 activin A receptor, type IB /FL=gb:NM_020328.1 gb:L10126.1 NM_020328 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 208220_x_at NM_001143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001143.1 /DEF=Homo sapiens amelogenin (Y chromosome) (AMELY), mRNA. /FEA=mRNA /GEN=AMELY /PROD=amelogenin (Y chromosome) /DB_XREF=gi:4502072 /UG=Hs.1238 amelogenin (Y chromosome) /FL=gb:M86933.1 gb:NM_001143.1 NM_001143 amelogenin, Y-linked AMELY 266 NM_001143 0007275 // multicellular organismal development // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred by curator 0030345 // structural constituent of tooth enamel // inferred from direct assay 208221_s_at NM_003061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003061.1 /DEF=Homo sapiens slit (Drosophila) homolog 1 (SLIT1), mRNA. /FEA=mRNA /GEN=SLIT1 /PROD=slit (Drosophila) homolog 1 /DB_XREF=gi:4507060 /UG=Hs.133466 slit (Drosophila) homolog 1 /FL=gb:AB017167.1 gb:NM_003061.1 NM_003061 slit homolog 1 (Drosophila) SLIT1 6585 NM_003061 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0048853 // forebrain morphogenesis // non-traceable author statement /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051964 // negative regulation of synapse assembly // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 208222_at NM_020327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020327.1 /DEF=Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 2, mRNA. /FEA=mRNA /GEN=ACVR1B /PROD=activin A type IB receptor, isoform b precursor /DB_XREF=gi:10862691 /UG=Hs.99954 activin A receptor, type IB /FL=gb:NM_020327.1 gb:L10125.1 NM_020327 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 208223_s_at NM_020327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020327.1 /DEF=Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 2, mRNA. /FEA=mRNA /GEN=ACVR1B /PROD=activin A type IB receptor, isoform b precursor /DB_XREF=gi:10862691 /UG=Hs.99954 activin A receptor, type IB /FL=gb:NM_020327.1 gb:L10125.1 NM_020327 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 208224_at NM_002144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002144.1 /DEF=Homo sapiens homeo box B1 (HOXB1), mRNA. /FEA=mRNA /GEN=HOXB1 /PROD=homeo box B1 /DB_XREF=gi:4504462 /UG=Hs.99992 homeo box B1 /FL=gb:NM_002144.1 NM_002144 homeobox B1 HOXB1 3211 NM_002144 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021546 // rhombomere development // inferred from electronic annotation /// 0021570 // rhombomere 4 development // inferred from electronic annotation /// 0021571 // rhombomere 5 development // inferred from electronic annotation /// 0021612 // facial nerve structural organization // inferred from electronic annotation /// 0021754 // facial nucleus development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208225_at NM_022971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022971.1 /DEF=Homo sapiens fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) (FGFR2), transcript variant 4, mRNA. /FEA=mRNA /GEN=FGFR2 /PROD=fibroblast growth factor receptor 2, isoform 4precursor /DB_XREF=gi:13186256 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022971.1 gb:M87772.1 NM_022971 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 208226_x_at NM_004194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004194.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 22 (ADAM22), mRNA. /FEA=mRNA /GEN=ADAM22 /PROD=a disintegrin and metalloproteinase domain 22,isoform 4 preproprotein /DB_XREF=gi:4757721 /UG=Hs.158052 a disintegrin and metalloproteinase domain 22 /FL=gb:AB009671.1 gb:NM_004194.1 NM_004194 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 208227_x_at NM_021721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021721.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 22 (ADAM22), mRNA. /FEA=mRNA /GEN=ADAM22 /PROD=a disintegrin and metalloproteinase domain 22,isoform 5 preproprotein /DB_XREF=gi:11497042 /UG=Hs.158052 a disintegrin and metalloproteinase domain 22 /FL=gb:NM_021721.1 NM_021721 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 208228_s_at M87771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M87771.1 /DEF=Human secreted fibroblast growth factor receptor (K-sam-III) mRNA, complete cds. /FEA=mRNA /GEN=K-sam-III /PROD=fibroblast growth factor receptor /DB_XREF=gi:186781 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022970.1 gb:M87771.1 M87771 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 208229_at NM_022975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022975.1 /DEF=Homo sapiens fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) (FGFR2), transcript variant 8, mRNA. /FEA=mRNA /GEN=FGFR2 /PROD=fibroblast growth factor receptor 2, isoform 8precursor /DB_XREF=gi:13186264 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022975.1 NM_022975 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 208230_s_at NM_013960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013960.1 /DEF=Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA. /FEA=mRNA /GEN=NRG1 /PROD=neuregulin 1 isoform ndf43 /DB_XREF=gi:7669519 /UG=Hs.172816 neuregulin 1 /FL=gb:U02326.1 gb:NM_013960.1 NM_013960 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 208231_at NM_013960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013960.1 /DEF=Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA. /FEA=mRNA /GEN=NRG1 /PROD=neuregulin 1 isoform ndf43 /DB_XREF=gi:7669519 /UG=Hs.172816 neuregulin 1 /FL=gb:U02326.1 gb:NM_013960.1 NM_013960 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 208232_x_at L12260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L12260.1 /DEF=Human recombinant glial growth factor 2 mRNA, complete cds and flanking regions. /FEA=mRNA /PROD=recombinant glial growth factor 2 /DB_XREF=gi:292047 /UG=Hs.172816 neuregulin 1 /FL=gb:L12260.1 gb:NM_013962.1 L12260 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 208233_at NM_013317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013317.1 /DEF=Homo sapiens lung type-I cell membrane-associated glycoprotein (T1A-2), transcript variant 1, mRNA. /FEA=mRNA /GEN=T1A-2 /PROD=lung type-I cell membrane-associatedglycoprotein, isoform 1 /DB_XREF=gi:7019416 /UG=Hs.135150 lung type-I cell membrane-associated glycoprotein /FL=gb:AF030427.1 gb:NM_013317.1 NM_013317 podoplanin PDPN 10630 NM_001006624 /// NM_001006625 /// NM_006474 /// NM_198389 /// XM_006710295 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006833 // water transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from sequence or structural similarity /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010572 // positive regulation of platelet activation // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0001726 // ruffle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005372 // water transmembrane transporter activity // inferred from sequence or structural similarity /// 0008517 // folic acid transporter activity // inferred from sequence or structural similarity /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015250 // water channel activity // inferred from sequence or structural similarity 208234_x_at NM_022976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022976.1 /DEF=Homo sapiens fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) (FGFR2), transcript variant 9, mRNA. /FEA=mRNA /GEN=FGFR2 /PROD=fibroblast growth factor receptor 2, isoform 9precursor /DB_XREF=gi:13186266 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022976.1 gb:U11814.1 NM_022976 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 208235_x_at NM_021123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021123.1 /DEF=Homo sapiens G antigen 7 (GAGE7), mRNA. /FEA=mRNA /GEN=GAGE7 /PROD=G antigen 7 /DB_XREF=gi:11024640 /UG=Hs.278606 G antigen 7 /FL=gb:NM_021123.1 gb:AF058988.1 NM_021123 G antigen 12B /// G antigen 12F /// G antigen 12G /// G antigen 12I /// G antigen 4 /// G antigen 5 /// G antigen 6 /// G antigen 7 GAGE12B /// GAGE12F /// GAGE12G /// GAGE12I /// GAGE4 /// GAGE5 /// GAGE6 /// GAGE7 2576 /// 2577 /// 2578 /// 2579 /// 26748 /// 645073 /// 729428 /// 100008586 NM_001098405 /// NM_001098409 /// NM_001127345 /// NM_001474 /// NM_001475 /// NM_001476 /// NM_001477 /// NM_021123 /// XM_005272739 /// XM_005278009 0006968 // cellular defense response // traceable author statement 0005515 // protein binding // inferred from physical interaction 208237_x_at AF155381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155381.1 /DEF=Homo sapiens metalloprotease-like, disintegrin-like, cysteine-rich protein 2 delta (ADAM22) mRNA, alternative splice product, complete cds. /FEA=mRNA /GEN=ADAM22 /PROD=metalloprotease-like, disintegrin-like,cysteine-rich protein 2 delta /DB_XREF=gi:8132432 /UG=Hs.158052 a disintegrin and metalloproteinase domain 22 /FL=gb:NM_021722.1 gb:AF155381.1 AF155381 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 208238_x_at NM_013344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013344.1 /DEF=Homo sapiens leucine zipper-like protein (LZLP), mRNA. /FEA=mRNA /GEN=LZLP /PROD=leucine zipper-like protein /DB_XREF=gi:7106350 /UG=Hs.278952 leucine zipper-like protein /FL=gb:AF159055.1 gb:NM_013344.1 NM_013344 208239_at NM_012185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012185.1 /DEF=Homo sapiens forkhead box E2 (FOXE2), mRNA. /FEA=mRNA /GEN=FOXE2 /PROD=forkhead box E2 /DB_XREF=gi:6912373 /UG=Hs.135634 forkhead box E2 /FL=gb:NM_012185.1 NM_012185 forkhead box E1 (thyroid transcription factor 2) FOXE1 2304 NM_004473 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006590 // thyroid hormone generation // not recorded /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0007389 // pattern specification process // not recorded /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // not recorded /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048538 // thymus development // inferred from expression pattern /// 0048562 // embryonic organ morphogenesis // not recorded /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0060022 // hard palate development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype /// 0060465 // pharynx development // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208240_s_at NM_013394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013394.1 /DEF=Homo sapiens acid fibroblast growth factor-like protein (GLIO703), mRNA. /FEA=mRNA /GEN=GLIO703 /PROD=acid fibroblast growth factor-like protein /DB_XREF=gi:7019394 /UG=Hs.278954 acid fibroblast growth factor-like protein /FL=gb:AF211169.1 gb:NM_013394.1 NM_013394 fibroblast growth factor 1 (acidic) FGF1 2246 NM_000800 /// NM_001144892 /// NM_001144934 /// NM_001144935 /// NM_001257205 /// NM_001257206 /// NM_001257207 /// NM_001257208 /// NM_001257209 /// NM_001257210 /// NM_001257211 /// NM_001257212 /// NM_033136 /// NM_033137 /// XM_005268390 /// XM_006714762 0001525 // angiogenesis // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from direct assay /// 0060681 // branch elongation involved in ureteric bud branching // inferred from direct assay /// 0072163 // mesonephric epithelium development // inferred from direct assay /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0044548 // S100 protein binding // inferred from physical interaction 208241_at NM_004495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004495.1 /DEF=Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma, mRNA. /FEA=mRNA /GEN=NRG1 /PROD=neuregulin 1 isoform HRG-gamma /DB_XREF=gi:4758525 /UG=Hs.172816 neuregulin 1 /FL=gb:AF026146.1 gb:NM_004495.1 NM_004495 neuregulin 1 NRG1 3084 NM_001159995 /// NM_001159996 /// NM_001159999 /// NM_001160001 /// NM_001160002 /// NM_001160004 /// NM_001160005 /// NM_001160007 /// NM_001160008 /// NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013962 /// NM_013964 /// XM_005273485 /// XM_005273486 /// XM_005273487 /// XM_006716335 0000165 // MAPK cascade // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from direct assay /// 0007154 // cell communication // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0014032 // neural crest cell development // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0021781 // glial cell fate commitment // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030879 // mammary gland development // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // traceable author statement /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043624 // cellular protein complex disassembly // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from direct assay /// 0060956 // endocardial cell differentiation // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005176 // ErbB-2 class receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred by curator /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // non-traceable author statement /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043125 // ErbB-3 class receptor binding // inferred from physical interaction 208242_at NM_013435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013435.1 /DEF=Homo sapiens retinal homeobox protein (RX), mRNA. /FEA=mRNA /GEN=RX /PROD=retinal homeobox protein /DB_XREF=gi:7305450 /UG=Hs.278957 retinal homeobox protein /FL=gb:AF115392.1 gb:NM_013435.1 NM_013435 retina and anterior neural fold homeobox RAX 30062 NM_013435 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060173 // limb development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208243_s_at NM_016083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016083.1 /DEF=Homo sapiens central cannabinoid receptor (CB1K5), mRNA. /FEA=mRNA /GEN=CB1K5 /PROD=central cannabinoid receptor /DB_XREF=gi:7705313 /UG=Hs.278974 central cannabinoid receptor /FL=gb:AF107262.1 gb:NM_016083.1 NM_016083 cannabinoid receptor 1 (brain) CNR1 1268 NM_001160226 /// NM_001160258 /// NM_001160259 /// NM_001160260 /// NM_016083 /// NM_033181 /// XM_005248650 /// XM_006715330 0002866 // positive regulation of acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0031622 // positive regulation of fever generation // inferred from electronic annotation /// 0031999 // negative regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033004 // negative regulation of mast cell activation // inferred from electronic annotation /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038171 // cannabinoid signaling pathway // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043271 // negative regulation of ion transport // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045759 // negative regulation of action potential // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0060405 // regulation of penile erection // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004949 // cannabinoid receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from electronic annotation 208244_at NM_001201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001201.1 /DEF=Homo sapiens bone morphogenetic protein 3 (osteogenic) (BMP3), mRNA. /FEA=mRNA /GEN=BMP3 /PROD=bone morphogenetic protein 3 (osteogenic)precursor /DB_XREF=gi:4557370 /UG=Hs.121507 bone morphogenetic protein 3 (osteogenic) /FL=gb:NM_001201.1 NM_001201 bone morphogenetic protein 3 BMP3 651 NM_001201 /// XM_006714291 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0070700 // BMP receptor binding // inferred from physical interaction 208245_at NM_004250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004250.1 /DEF=Homo sapiens RAB9, member RAS oncogene family, pseudogene 1 (RAB9P1), mRNA. /FEA=mRNA /GEN=RAB9P1 /PROD=RAB9, member RAS oncogene family, pseudogene 1 /DB_XREF=gi:4759013 /UG=Hs.158296 RAB9, member RAS oncogene family, pseudogene 1 /FL=gb:U44105.1 gb:NM_004250.1 NM_004250 RAB9B, member RAS oncogene family pseudogene 1 RAB9BP1 9366 NR_000039 208246_x_at NM_017618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017618.1 /DEF=Homo sapiens hypothetical protein FLJ20006 (FLJ20006), mRNA. /FEA=mRNA /GEN=FLJ20006 /PROD=hypothetical protein FLJ20006 /DB_XREF=gi:8923014 /UG=Hs.279007 hypothetical protein FLJ20006 /FL=gb:NM_017618.1 NM_017618 RP11-403P17.4 208247_at NM_001213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001213.1 /DEF=Homo sapiens chromosome 1 open reading frame 1 (C1ORF1), mRNA. /FEA=mRNA /GEN=C1ORF1 /PROD=chromosome 1 open reading frame 1 /DB_XREF=gi:4557380 /UG=Hs.158302 chromosome 1 open reading frame 1 /FL=gb:U88965.1 gb:NM_001213.1 NM_001213 ERC2 intronic transcript 1 (non-protein coding) ERC2-IT1 711 NR_024615 208248_x_at NM_001642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001642.1 /DEF=Homo sapiens amyloid beta (A4) precursor-like protein 2 (APLP2), mRNA. /FEA=mRNA /GEN=APLP2 /PROD=amyloid beta (A4) precursor-like protein 2 /DB_XREF=gi:4502146 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:L09209.1 gb:NM_001642.1 gb:L27631.1 gb:AF168956.1 NM_001642 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 208249_s_at NM_014305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014305.1 /DEF=Homo sapiens dTDP-D-glucose 4,6-dehydratase (TDPGD), mRNA. /FEA=mRNA /GEN=TDPGD /PROD=dTDP-D-glucose 4,6-dehydratase /DB_XREF=gi:7657640 /UG=Hs.12393 dTDP-D-glucose 4,6-dehydratase /FL=gb:NM_014305.1 NM_014305 TDP-glucose 4,6-dehydratase TGDS 23483 NM_014305 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009225 // nucleotide-sugar metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0008460 // dTDP-glucose 4,6-dehydratase activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 208250_s_at NM_004406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004406.1 /DEF=Homo sapiens deleted in malignant brain tumors 1 (DMBT1), transcript variant 1, mRNA. /FEA=mRNA /GEN=DMBT1 /PROD=deleted in malignant brain tumors 1 isoform aprecursor /DB_XREF=gi:4758169 /UG=Hs.279611 deleted in malignant brain tumors 1 /FL=gb:NM_004406.1 NM_004406 deleted in malignant brain tumors 1 DMBT1 1755 NM_004406 /// NM_007329 /// NM_017579 /// XM_006717660 /// XM_006717661 /// XM_006717662 /// XM_006717663 /// XM_006717664 /// XM_006717665 /// XM_006717666 /// XM_006717667 /// XM_006717668 /// XM_006717669 /// XM_006717670 /// XM_006717671 /// XM_006717672 /// XM_006717673 /// XM_006717674 /// XM_006717675 /// XM_006717676 /// XM_006717677 /// XM_006717678 /// XM_006717679 0001824 // blastocyst development // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0002221 // pattern recognition receptor signaling pathway // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // non-traceable author statement /// 0030855 // epithelial cell differentiation // traceable author statement /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0043152 // induction of bacterial agglutination // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from sequence or structural similarity /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005044 // scavenger receptor activity // non-traceable author statement /// 0005044 // scavenger receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008329 // signaling pattern recognition receptor activity // traceable author statement /// 0035375 // zymogen binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // traceable author statement 208251_at NM_004978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004978.1 /DEF=Homo sapiens potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), mRNA. /FEA=mRNA /GEN=KCNC4 /PROD=potassium voltage-gated channel, Shaw-relatedsubfamily, member 4 /DB_XREF=gi:4826789 /UG=Hs.124212 potassium voltage-gated channel, Shaw-related subfamily, member 4 /FL=gb:M64676.1 gb:NM_004978.1 NM_004978 potassium voltage-gated channel, Shaw-related subfamily, member 4 KCNC4 3749 NM_001039574 /// NM_004978 /// NM_153763 /// NR_036437 /// XM_006710625 /// XM_006710626 /// XM_006710627 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 208252_s_at NM_004273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004273.1 /DEF=Homo sapiens carbohydrate (chondroitin 6keratan) sulfotransferase 3 (CHST3), mRNA. /FEA=mRNA /GEN=CHST3 /PROD=carbohydrate (chondroitin 6keratan)sulfotransferase 3 /DB_XREF=gi:4757985 /UG=Hs.158304 carbohydrate (chondroitin 6keratan) sulfotransferase 3 /FL=gb:AB012192.1 gb:NM_004273.1 NM_004273 carbohydrate (chondroitin 6) sulfotransferase 3 CHST3 9469 NM_004273 /// XM_006718075 0005975 // carbohydrate metabolic process // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0008459 // chondroitin 6-sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0050698 // proteoglycan sulfotransferase activity // inferred from electronic annotation 208253_at NM_014442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014442.1 /DEF=Homo sapiens sialic acid binding Ig-like lectin 8 (SIGLEC8), mRNA. /FEA=mRNA /GEN=SIGLEC8 /PROD=sialic acid binding Ig-like lectin 8 /DB_XREF=gi:7657571 /UG=Hs.279751 sialic acid binding Ig-like lectin 8 /FL=gb:AF195092.1 gb:AF223403.1 gb:NM_014442.1 NM_014442 sialic acid binding Ig-like lectin 8 SIGLEC8 27181 NM_014442 /// XR_243922 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement 208254_at NM_004908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004908.1 /DEF=Homo sapiens pre-TNK cell associated protein (6H9A), mRNA. /FEA=mRNA /GEN=6H9A /PROD=pre-TNK cell associated protein /DB_XREF=gi:4757703 /UG=Hs.280 pre-TNK cell associated protein /FL=gb:L17330.1 gb:NM_004908.1 NM_004908 208255_s_at NM_012181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012181.1 /DEF=Homo sapiens FK506-binding protein 8 (38kD) (FKBP8), mRNA. /FEA=mRNA /GEN=FKBP8 /PROD=FK506-binding protein 8 (38kD) /DB_XREF=gi:6912367 /UG=Hs.173464 FK506-binding protein 8 (38kD) /FL=gb:NM_012181.1 gb:L37033.1 NM_012181 FK506 binding protein 8, 38kDa FKBP8 23770 NM_012181 /// XM_005259841 /// XM_005259842 /// XM_005259844 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030510 // regulation of BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005740 // mitochondrial envelope // /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208256_at NM_001405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001405.1 /DEF=Homo sapiens ephrin-A2 (EFNA2), mRNA. /FEA=mRNA /GEN=EFNA2 /PROD=ephrin-A2 /DB_XREF=gi:4503484 /UG=Hs.158306 ephrin-A2 /FL=gb:NM_001405.1 NM_001405 ephrin-A2 EFNA2 1943 NM_001405 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // not recorded /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030316 // osteoclast differentiation // not recorded /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0046849 // bone remodeling // not recorded /// 0046849 // bone remodeling // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // not recorded /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0046875 // ephrin receptor binding // not recorded 208257_x_at NM_006905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006905.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 1 (PSG1), mRNA. /FEA=mRNA /GEN=PSG1 /PROD=pregnancy specific beta-1-glycoprotein 1 /DB_XREF=gi:5902029 /UG=Hs.173609 pregnancy specific beta-1-glycoprotein 1 /FL=gb:M17908.1 gb:NM_006905.1 NM_006905 pregnancy specific beta-1-glycoprotein 1 PSG1 5669 NM_001184825 /// NM_001184826 /// NM_006905 /// XM_005259063 /// XM_005259064 /// XM_005259065 /// XM_005259066 /// XM_005259067 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 208258_s_at NM_006478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006478.1 /DEF=Homo sapiens GAS2-related on chromosome 22 (GAR22), mRNA. /FEA=mRNA /GEN=GAR22 /PROD=GAS2-related on chromosome 22 /DB_XREF=gi:5453657 /UG=Hs.282258 GAS2-related on chromosome 22 /FL=gb:NM_006478.1 NM_006478 growth arrest-specific 2 like 1 GAS2L1 10634 NM_001278730 /// NM_006478 /// NM_152236 /// NM_152237 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation 0008017 // microtubule binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 208259_x_at NM_021057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021057.1 /DEF=Homo sapiens interferon, alpha 7 (IFNA7), mRNA. /FEA=mRNA /GEN=IFNA7 /PROD=interferon, alpha 7 /DB_XREF=gi:10800141 /UG=Hs.282274 interferon, alpha 7 /FL=gb:NM_021057.1 gb:M34913.1 NM_021057 interferon, alpha 7 IFNA7 3444 NM_021057 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007267 // cell-cell signaling // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // not recorded 208260_at NM_000707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000707.2 /DEF=Homo sapiens arginine vasopressin receptor 1B (AVPR1B), mRNA. /FEA=mRNA /GEN=AVPR1B /PROD=arginine vasopressin receptor 1B /DB_XREF=gi:13112055 /UG=Hs.1372 arginine vasopressin receptor 1B /FL=gb:NM_000707.2 gb:AF030512.1 gb:AF101726.1 gb:D31833.1 gb:L37112.1 NM_000707 arginine vasopressin receptor 1B AVPR1B 553 NM_000707 0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement 208261_x_at NM_002171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002171.1 /DEF=Homo sapiens interferon, alpha 10 (IFNA10), mRNA. /FEA=mRNA /GEN=IFNA10 /PROD=interferon, alpha 10 /DB_XREF=gi:4504588 /UG=Hs.282275 interferon, alpha 10 /FL=gb:NM_002171.1 NM_002171 interferon, alpha 10 IFNA10 3446 NM_002171 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // not recorded 208262_x_at NM_000243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000243.1 /DEF=Homo sapiens Mediterranean fever (MEFV), mRNA. /FEA=mRNA /GEN=MEFV /PROD=Mediterranean fever protein /DB_XREF=gi:4557742 /UG=Hs.173730 Mediterranean fever /FL=gb:AF018080.1 gb:NM_000243.1 NM_000243 Mediterranean fever MEFV 4210 NM_000243 /// NM_001198536 /// XM_006720879 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0032691 // negative regulation of interleukin-1 beta production // inferred from mutant phenotype /// 0032695 // negative regulation of interleukin-12 production // inferred from mutant phenotype /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0071641 // negative regulation of macrophage inflammatory protein 1 alpha production // inferred from mutant phenotype /// 2001056 // positive regulation of cysteine-type endopeptidase activity // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208263_at NM_018581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018581.1 /DEF=Homo sapiens hypothetical protein PRO1318 (PRO1318), mRNA. /FEA=mRNA /GEN=PRO1318 /PROD=hypothetical protein PRO1318 /DB_XREF=gi:8924033 /UG=Hs.283056 hypothetical protein PRO1318 /FL=gb:AF116633.1 gb:NM_018581.1 NM_018581 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0005047 // signal recognition particle binding // inferred from physical interaction /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208264_s_at NM_003758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003758.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD) (EIF3S1), mRNA. /FEA=mRNA /GEN=EIF3S1 /PROD=eukaryotic translation initiation factor 3,subunit 1 (alpha, 35kD) /DB_XREF=gi:4503510 /UG=Hs.173987 eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD) /FL=gb:U97670.1 gb:NM_003758.1 NM_003758 eukaryotic translation initiation factor 3, subunit J EIF3J 8669 NM_001284335 /// NM_001284336 /// NM_003758 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 208265_at NM_020161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020161.1 /DEF=Homo sapiens hypothetical protein DKFZp547H025 (DKFZp547H025), mRNA. /FEA=mRNA /GEN=DKFZp547H025 /PROD=hypothetical protein DKFZp547H025 /DB_XREF=gi:9910195 /UG=Hs.283092 hypothetical protein DKFZp547H025 /FL=gb:NM_020161.1 NM_020161 chromosome 2 open reading frame 83 C2orf83 56918 NM_001162483 /// NM_020161 0006810 // transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0005542 // folic acid binding // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation 208266_at NM_020237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020237.1 /DEF=Homo sapiens MOST-1 protein (MOST-1), mRNA. /FEA=mRNA /GEN=MOST-1 /PROD=MOST-1 protein /DB_XREF=gi:9910447 /UG=Hs.283098 MOST-1 protein /FL=gb:AF220264.1 gb:NM_020237.1 NM_020237 chromosome 8 open reading frame 17 C8orf17 100507249 NM_020237 /// XM_003118604 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 208267_at NM_019841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019841.1 /DEF=Homo sapiens epithelial calcium channel 1 (ECAC1), mRNA. /FEA=mRNA /GEN=ECAC1 /PROD=epithelial calcium channel 1 /DB_XREF=gi:9789940 /UG=Hs.283369 epithelial calcium channel 1 /FL=gb:NM_019841.1 NM_019841 transient receptor potential cation channel, subfamily V, member 5 TRPV5 56302 NM_019841 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006816 // calcium ion transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060402 // calcium ion transport into cytosol // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 208268_at NM_021777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021777.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 28 (ADAM28), transcript variant 3, mRNA. /FEA=mRNA /GEN=ADAM28 /PROD=a disintegrin and metalloproteinase domain 28,isoform 3 preproprotein /DB_XREF=gi:11496993 /UG=Hs.174030 a disintegrin and metalloproteinase domain 28 /FL=gb:NM_021777.1 gb:AF137335.1 NM_021777 ADAM metallopeptidase domain 28 ADAM28 10863 NM_014265 /// NM_021777 /// XM_005273378 /// XM_005273379 /// XM_005273380 /// XM_005273381 /// XM_005273382 /// XM_006716273 /// XM_006716274 /// XM_006716275 /// XR_247120 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208269_s_at NM_021777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021777.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 28 (ADAM28), transcript variant 3, mRNA. /FEA=mRNA /GEN=ADAM28 /PROD=a disintegrin and metalloproteinase domain 28,isoform 3 preproprotein /DB_XREF=gi:11496993 /UG=Hs.174030 a disintegrin and metalloproteinase domain 28 /FL=gb:NM_021777.1 gb:AF137335.1 NM_021777 ADAM metallopeptidase domain 28 ADAM28 10863 NM_014265 /// NM_021777 /// XM_005273378 /// XM_005273379 /// XM_005273380 /// XM_005273381 /// XM_005273382 /// XM_006716273 /// XM_006716274 /// XM_006716275 /// XR_247120 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208270_s_at NM_020216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020216.2 /DEF=Homo sapiens arginyl aminopeptidase (aminopeptidase B) (RNPEP), mRNA. /FEA=mRNA /GEN=RNPEP /PROD=arginyl aminopeptidase (aminopeptidase B) /DB_XREF=gi:13443030 /UG=Hs.283667 arginyl aminopeptidase (aminopeptidase B) /FL=gb:NM_020216.2 NM_020216 arginyl aminopeptidase (aminopeptidase B) RNPEP 6051 NM_020216 /// XM_005245418 /// XM_005245419 /// XM_005245420 /// XM_005245421 0000209 // protein polyubiquitination // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006508 // proteolysis // inferred by curator /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from sequence or structural similarity /// 0004177 // aminopeptidase activity // non-traceable author statement /// 0004301 // epoxide hydrolase activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208271_at NM_020144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020144.1 /DEF=Homo sapiens testis-specific poly(A) polymerase (PAPT), mRNA. /FEA=mRNA /GEN=PAPT /PROD=testis-specific poly(A) polymerase /DB_XREF=gi:9910477 /UG=Hs.283694 poly(A) polymerase beta (testis specific) /FL=gb:AF218840.1 gb:NM_020144.1 NM_020144 poly(A) polymerase beta (testis specific) PAPOLB 56903 NM_020144 0000398 // mRNA splicing, via spliceosome // not recorded /// 0006369 // termination of RNA polymerase II transcription // not recorded /// 0006378 // mRNA polyadenylation // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0043631 // RNA polyadenylation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208272_at NM_007321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007321.1 /DEF=Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-c, mRNA. /FEA=mRNA /GEN=RANBP3 /PROD=RAN binding protein 3, isoform RANBP3-c /DB_XREF=gi:6466463 /UG=Hs.176657 RAN binding protein 3 /FL=gb:NM_007321.1 NM_007321 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 208273_at NM_020394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020394.1 /DEF=Homo sapiens zinc finger protein SBZF3 (LOC57116), mRNA. /FEA=mRNA /GEN=LOC57116 /PROD=zinc finger protein SBZF3 /DB_XREF=gi:9966870 /UG=Hs.283726 zinc finger protein SBZF3 /FL=gb:AF242519.1 gb:NM_020394.1 NM_020394 zinc finger protein 670 /// ZNF670-ZNF695 readthrough (NMD candidate) /// zinc finger protein 695 ZNF670 /// ZNF670-ZNF695 /// ZNF695 57116 /// 93474 /// 100533111 NM_001204220 /// NM_001204221 /// NM_020394 /// NM_033213 /// NR_037892 /// NR_037894 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208274_at NM_022375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022375.1 /DEF=Homo sapiens oculomedin (OCLM), mRNA. /FEA=mRNA /GEN=OCLM /PROD=oculomedin /DB_XREF=gi:11693179 /UG=Hs.283759 oculomedin /FL=gb:NM_022375.1 gb:AF142063.1 NM_022375 oculomedin OCLM 10896 NM_022375 0007601 // visual perception // traceable author statement 208275_x_at NM_003577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003577.1 /DEF=Homo sapiens undifferentiated embryonic cell transcription factor 1 (UTF1), mRNA. /FEA=mRNA /GEN=UTF1 /PROD=undifferentiated embryonic cell transcriptionfactor 1 /DB_XREF=gi:4507858 /UG=Hs.158307 undifferentiated embryonic cell transcription factor 1 /FL=gb:AB011076.1 gb:NM_003577.1 NM_003577 undifferentiated embryonic cell transcription factor 1 UTF1 8433 NM_003577 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 208276_at NM_016420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_016420.1 /DEF=Homo sapiens clone FLB7343 (LOC51221), mRNA. /FEA=mRNA /GEN=LOC51221 /PROD=clone FLB7343 /DB_XREF=gi:10092636 /UG=Hs.283774 clone FLB7343 /FL=gb:NM_016420.1 gb:AF113698.1 NM_016420 208277_at NM_005029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005029.1 /DEF=Homo sapiens paired-like homeodomain transcription factor 3 (PITX3), mRNA. /FEA=mRNA /GEN=PITX3 /PROD=paired-like homeodomain transcription factor 3 /DB_XREF=gi:4826911 /UG=Hs.137568 paired-like homeodomain transcription factor 3 /FL=gb:AF041339.1 gb:NM_005029.1 NM_005029 paired-like homeodomain 3 PITX3 5309 NM_005029 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208278_s_at NM_016420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016420.1 /DEF=Homo sapiens clone FLB7343 (LOC51221), mRNA. /FEA=mRNA /GEN=LOC51221 /PROD=clone FLB7343 /DB_XREF=gi:10092636 /UG=Hs.283774 clone FLB7343 /FL=gb:NM_016420.1 gb:AF113698.1 NM_016420 208279_s_at NM_006382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006382.1 /DEF=Homo sapiens chromosome 17 open reading frame 1A (C17ORF1A), mRNA. /FEA=mRNA /GEN=C17ORF1A /PROD=chromosome 17 open reading frame 1A /DB_XREF=gi:5453580 /UG=Hs.158313 chromosome 17 open reading frame 1A /FL=gb:U65652.1 gb:NM_006382.1 NM_006382 CMT1A duplicated region transcript 1 CDRT1 374286 NM_001282540 /// NM_006382 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 208280_at NM_006382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006382.1 /DEF=Homo sapiens chromosome 17 open reading frame 1A (C17ORF1A), mRNA. /FEA=mRNA /GEN=C17ORF1A /PROD=chromosome 17 open reading frame 1A /DB_XREF=gi:5453580 /UG=Hs.158313 chromosome 17 open reading frame 1A /FL=gb:U65652.1 gb:NM_006382.1 NM_006382 CMT1A duplicated region transcript 1 CDRT1 374286 NM_001282540 /// NM_006382 208281_x_at NM_020364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020364.1 /DEF=Homo sapiens deleted in azoospermia 3 (DAZ3), mRNA. /FEA=mRNA /GEN=DAZ3 /PROD=deleted in azoospermia 3 /DB_XREF=gi:11036657 /UG=Hs.283812 deleted in azoospermia 3 /FL=gb:NM_020364.1 gb:AF248481.1 NM_020364 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 208282_x_at NM_020363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020363.1 /DEF=Homo sapiens deleted in azoospermia 2 (DAZ2), mRNA. /FEA=mRNA /GEN=DAZ2 /PROD=deleted in azoospermia 2 /DB_XREF=gi:11036659 /UG=Hs.283813 deleted in azoospermia 2 /FL=gb:NM_020363.1 gb:AF248480.1 NM_020363 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 208283_at NM_001468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001468.1 /DEF=Homo sapiens G antigen 1 (GAGE1), mRNA. /FEA=mRNA /GEN=GAGE1 /PROD=G antigen 1 /DB_XREF=gi:4503876 /UG=Hs.176660 G antigen 1 /FL=gb:NM_001468.1 gb:U19142.1 NM_001468 G antigen 1 GAGE1 2543 NM_001040663 /// NM_001468 /// NR_102272 0006968 // cellular defense response // traceable author statement 208284_x_at NM_013421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013421.1 /DEF=Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA. /FEA=mRNA /GEN=GGT1 /PROD=gamma-glutamyltransferase 1 precursor /DB_XREF=gi:9845490 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:J04131.1 gb:NM_013421.1 NM_013421 gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 2 /// gamma-glutamyltransferase light chain 1 /// gamma-glutamyltransferase light chain 2 GGT1 /// GGT2 /// GGTLC1 /// GGTLC2 2678 /// 91227 /// 92086 /// 728441 NM_001032364 /// NM_001032365 /// NM_001282879 /// NM_001288833 /// NM_005265 /// NM_013421 /// NM_013430 /// NM_080839 /// NM_080920 /// NM_178311 /// NM_178312 /// NM_199127 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_005261888 /// XM_005261890 /// XM_006723661 /// XM_006723662 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 /// XM_006724392 /// XM_006724393 /// XM_006724394 /// XM_006724395 /// XM_006724396 /// XM_006724397 /// XM_006726820 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from mutant phenotype /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // inferred from direct assay /// 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay 208285_at NM_017506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017506.1 /DEF=Homo sapiens olfactory receptor, family 7, subfamily C, member 1 (OR7C1), mRNA. /FEA=mRNA /GEN=OR7C1 /PROD=olfactory receptor, family 7, subfamily C,member 1 /DB_XREF=gi:9506798 /UG=Hs.137573 olfactory receptor, family 7, subfamily C, member 1 /FL=gb:NM_017506.1 NM_017506 olfactory receptor, family 7, subfamily A, member 5 OR7A5 26659 NM_017506 /// XM_006722722 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement 208286_x_at NM_002701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002701.1 /DEF=Homo sapiens POU domain, class 5, transcription factor 1 (POU5F1), mRNA. /FEA=mRNA /GEN=POU5F1 /PROD=POU domain, class 5, transcription factor 1 /DB_XREF=gi:4505966 /UG=Hs.2860 POU domain, class 5, transcription factor 1 /FL=gb:NM_002701.1 NM_002701 POU class 5 homeobox 1 /// POU class 5 homeobox 1B /// POU class 5 homeobox 1 pseudogene 3 /// POU class 5 homeobox 1 pseudogene 4 POU5F1 /// POU5F1B /// POU5F1P3 /// POU5F1P4 5460 /// 5462 /// 642559 /// 645682 NM_001159542 /// NM_001173531 /// NM_001285986 /// NM_001285987 /// NM_002701 /// NM_203289 /// NR_002304 /// NR_034180 /// NR_036440 0001714 // endodermal cell fate specification // inferred from direct assay /// 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0003130 // BMP signaling pathway involved in heart induction // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009786 // regulation of asymmetric cell division // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from direct assay /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060795 // cell fate commitment involved in formation of primary germ layer // inferred from mutant phenotype /// 0060913 // cardiac cell fate determination // inferred from direct assay /// 0060965 // negative regulation of gene silencing by miRNA // inferred from mutant phenotype /// 0090081 // regulation of heart induction by regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090308 // regulation of methylation-dependent chromatin silencing // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208287_at NM_005844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005844.1 /DEF=Homo sapiens PERB11 family member in MHC class I region (HCGIX), mRNA. /FEA=mRNA /GEN=HCGIX /PROD=PERB11 family member in MHC class I region /DB_XREF=gi:5031730 /UG=Hs.17704 PERB11 family member in MHC class I region /FL=gb:NM_005844.1 NM_005844 HLA complex group 9 (non-protein coding) HCG9 10255 NM_005844 /// NR_028032 208288_at NM_003742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003742.1 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 11 (ABCB11), mRNA. /FEA=mRNA /GEN=ABCB11 /PROD=ATP-binding cassette, sub-family B (MDRTAP),member 11 /DB_XREF=gi:4502456 /UG=Hs.158316 ATP-binding cassette, sub-family B (MDRTAP), member 11 /FL=gb:AF091582.1 gb:NM_003742.1 NM_003742 ATP-binding cassette, sub-family B (MDR/TAP), member 11 ABCB11 8647 NM_003742 /// XM_006712817 /// XM_006712818 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0015722 // canalicular bile acid transport // not recorded /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded 0000139 // Golgi membrane // /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0016324 // apical plasma membrane // /// 0045177 // apical part of cell // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008554 // sodium-exporting ATPase activity, phosphorylative mechanism // traceable author statement /// 0015126 // canalicular bile acid transmembrane transporter activity // not recorded /// 0015432 // bile acid-exporting ATPase activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 208289_s_at NM_004879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004879.2 /DEF=Homo sapiens etoposide-induced mRNA (PIG8), mRNA. /FEA=mRNA /GEN=PIG8 /PROD=etoposide-induced mRNA /DB_XREF=gi:6631103 /UG=Hs.286027 etoposide-induced mRNA /FL=gb:NM_004879.2 NM_004879 etoposide induced 2.4 EI24 9538 NM_001007277 /// NM_001290135 /// NM_004879 /// NR_110769 /// NR_110770 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 208290_s_at NM_001969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001969.1 /DEF=Homo sapiens eukaryotic translation initiation factor 5 (EIF5), mRNA. /FEA=mRNA /GEN=EIF5 /PROD=eukaryotic translation initiation factor 5 /DB_XREF=gi:4503542 /UG=Hs.286236 eukaryotic translation initiation factor 5 /FL=gb:U49436.1 gb:NM_001969.1 NM_001969 eukaryotic translation initiation factor 5 EIF5 1983 NM_001969 /// NM_183004 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208291_s_at NM_000360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000360.1 /DEF=Homo sapiens tyrosine hydroxylase (TH), mRNA. /FEA=mRNA /GEN=TH /PROD=tyrosine hydroxylase /DB_XREF=gi:4507480 /UG=Hs.178237 tyrosine hydroxylase /FL=gb:NM_000360.1 NM_000360 tyrosine hydroxylase TH 7054 NM_000360 /// NM_199292 /// NM_199293 0001666 // response to hypoxia // inferred from direct assay /// 0001963 // synaptic transmission, dopaminergic // inferred from sequence or structural similarity /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0003007 // heart morphogenesis // non-traceable author statement /// 0006585 // dopamine biosynthetic process from tyrosine // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008016 // regulation of heart contraction // inferred from sequence or structural similarity /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0009414 // response to water deprivation // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0015842 // synaptic vesicle amine transport // inferred from electronic annotation /// 0016137 // glycoside metabolic process // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033076 // isoquinoline alkaloid metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042214 // terpene metabolic process // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from direct assay /// 0042418 // epinephrine biosynthetic process // inferred from direct assay /// 0042421 // norepinephrine biosynthetic process // inferred from direct assay /// 0042423 // catecholamine biosynthetic process // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043473 // pigmentation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0052314 // phytoalexin metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0033162 // melanosome membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043204 // perikaryon // inferred from sequence or structural similarity 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004511 // tyrosine 3-monooxygenase activity // inferred from direct assay /// 0004511 // tyrosine 3-monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // inferred from electronic annotation /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016714 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0034617 // tetrahydrobiopterin binding // inferred from electronic annotation /// 0035240 // dopamine binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208292_at NM_014482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014482.1 /DEF=Homo sapiens bone morphogenetic protein 10 (BMP10), mRNA. /FEA=mRNA /GEN=BMP10 /PROD=bone morphogenetic protein 10 /DB_XREF=gi:7656927 /UG=Hs.158317 bone morphogenetic protein 10 /FL=gb:AF101441.1 gb:NM_014482.1 NM_014482 bone morphogenetic protein 10 BMP10 27302 NM_014482 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from sequence or structural similarity /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from mutant phenotype /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055015 // ventricular cardiac muscle cell development // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060038 // cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060298 // positive regulation of sarcomere organization // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0033612 // receptor serine/threonine kinase binding // inferred from direct assay 208293_x_at NM_022581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022581.1 /DEF=Homo sapiens chorionic somatomammotropin hormone-like 1 (CSHL1), transcript variant 5, mRNA. /FEA=mRNA /GEN=CSHL1 /PROD=chorionic somatomammotropin hormone-like 1,isoform 5 precursor /DB_XREF=gi:12545380 /UG=Hs.287269 chorionic somatomammotropin hormone-like 1 /FL=gb:NM_022581.1 NM_022581 chorionic somatomammotropin hormone-like 1 CSHL1 1444 NM_001318 /// NM_022579 /// NM_022580 /// NM_022581 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208294_x_at NM_022578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022578.1 /DEF=Homo sapiens chorionic somatomammotropin hormone-like 1 (CSHL1), transcript variant 2, mRNA. /FEA=mRNA /GEN=CSHL1 /PROD=chorionic somatomammotropin hormone-like 1,isoform 2 /DB_XREF=gi:12545373 /UG=Hs.287269 chorionic somatomammotropin hormone-like 1 /FL=gb:NM_022578.1 NM_022578 chorionic somatomammotropin hormone-like 1 CSHL1 1444 NM_001318 /// NM_022579 /// NM_022580 /// NM_022581 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208295_x_at NM_022580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022580.1 /DEF=Homo sapiens chorionic somatomammotropin hormone-like 1 (CSHL1), transcript variant 4, mRNA. /FEA=mRNA /GEN=CSHL1 /PROD=chorionic somatomammotropin hormone-like 1,isoform 4 /DB_XREF=gi:12545377 /UG=Hs.287269 chorionic somatomammotropin hormone-like 1 /FL=gb:NM_022580.1 NM_022580 chorionic somatomammotropin hormone-like 1 CSHL1 1444 NM_001318 /// NM_022579 /// NM_022580 /// NM_022581 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208296_x_at NM_014350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014350.1 /DEF=Homo sapiens TNF-induced protein (GG2-1), mRNA. /FEA=mRNA /GEN=GG2-1 /PROD=TNF-induced protein /DB_XREF=gi:7657123 /UG=Hs.17839 TNF-induced protein /FL=gb:AF099936.1 gb:NM_014350.1 NM_014350 tumor necrosis factor, alpha-induced protein 8 TNFAIP8 25816 NM_001077654 /// NM_001286813 /// NM_001286814 /// NM_001286815 /// NM_001286817 /// NM_014350 /// XM_006714584 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype 208297_s_at NM_005665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005665.1 /DEF=Homo sapiens ecotropic viral integration site 5 (EVI5), mRNA. /FEA=mRNA /GEN=EVI5 /PROD=ecotropic viral integration site 5 /DB_XREF=gi:5031932 /UG=Hs.179747 ecotropic viral integration site 5 /FL=gb:AF042345.1 gb:NM_005665.1 NM_005665 ecotropic viral integration site 5 EVI5 7813 NM_005665 /// XM_005271179 /// XM_005271180 /// XM_005271182 /// XM_006710884 /// XM_006710885 /// XM_006710886 /// XM_006710887 /// XM_006710888 /// XM_006710889 /// XM_006710890 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208298_at NM_005665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005665.1 /DEF=Homo sapiens ecotropic viral integration site 5 (EVI5), mRNA. /FEA=mRNA /GEN=EVI5 /PROD=ecotropic viral integration site 5 /DB_XREF=gi:5031932 /UG=Hs.179747 ecotropic viral integration site 5 /FL=gb:AF042345.1 gb:NM_005665.1 NM_005665 ecotropic viral integration site 5 EVI5 7813 NM_005665 /// XM_005271179 /// XM_005271180 /// XM_005271182 /// XM_006710884 /// XM_006710885 /// XM_006710886 /// XM_006710887 /// XM_006710888 /// XM_006710889 /// XM_006710890 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208299_at NM_021096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021096.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 1I subunit (CACNA1I), mRNA. /FEA=mRNA /GEN=CACNA1I /PROD=calcium channel, voltage-dependent, alpha 1Isubunit /DB_XREF=gi:10863882 /UG=Hs.125116 calcium channel, voltage-dependent, alpha 1I subunit /FL=gb:NM_021096.1 gb:AF129133.1 NM_021096 calcium channel, voltage-dependent, T type, alpha 1I subunit CACNA1I 8911 NM_001003406 /// NM_021096 /// XM_006724348 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030317 // sperm motility // not recorded /// 0030431 // sleep // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008332 // low voltage-gated calcium channel activity // non-traceable author statement 208300_at NM_002842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002842.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, H (PTPRH), mRNA. /FEA=mRNA /GEN=PTPRH /PROD=protein tyrosine phosphatase, receptor type, H /DB_XREF=gi:4506312 /UG=Hs.179770 protein tyrosine phosphatase, receptor type, H /FL=gb:NM_002842.1 gb:D15049.1 NM_002842 protein tyrosine phosphatase, receptor type, H PTPRH 5794 NM_001161440 /// NM_002842 /// XM_006723312 0006470 // protein dephosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 208301_at NM_025033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025033.1 /DEF=Homo sapiens hypothetical protein FLJ21277 (FLJ21277), mRNA. /FEA=mRNA /GEN=FLJ21277 /PROD=hypothetical protein FLJ21277 /DB_XREF=gi:13376559 /UG=Hs.287654 hypothetical protein FLJ21277 /FL=gb:NM_025033.1 NM_025033 AC007292.3 208302_at NM_021182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021182.1 /DEF=Homo sapiens minor histocompatibility antigen HB-1 (HB-1), mRNA. /FEA=mRNA /GEN=HB-1 /PROD=minor histocompatibility antigen HB-1 /DB_XREF=gi:10863982 /UG=Hs.158320 minor histocompatibility antigen HB-1 /FL=gb:NM_021182.1 gb:AF103884.1 NM_021182 histocompatibility (minor) HB-1 HMHB1 57824 NM_021182 0002376 // immune system process // inferred from electronic annotation 208303_s_at NM_022148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022148.1 /DEF=Homo sapiens cytokine receptor-like factor 2 (CRLF2), mRNA. /FEA=mRNA /GEN=CRLF2 /PROD=cytokine receptor-like factor 2 /DB_XREF=gi:13375623 /UG=Hs.287729 cytokine receptor-like factor 2 /FL=gb:NM_022148.1 NM_022148 cytokine receptor-like factor 2 CRLF2 64109 NM_001012288 /// NM_022148 /// NR_110830 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 208304_at NM_001837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001837.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 3 (CCR3), mRNA. /FEA=mRNA /GEN=CCR3 /PROD=chemokine (C-C motif) receptor 3 /DB_XREF=gi:4502636 /UG=Hs.158324 chemokine (C-C motif) receptor 3 /FL=gb:U28694.1 gb:AF026535.1 gb:NM_001837.1 NM_001837 chemokine (C-C motif) receptor 3 CCR3 1232 NM_001164680 /// NM_001837 /// NM_178328 /// NM_178329 /// XM_006712960 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035476 // angioblast cell migration // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048245 // eosinophil chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 208305_at NM_000926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000926.1 /DEF=Homo sapiens progesterone receptor (PGR), mRNA. /FEA=mRNA /GEN=PGR /PROD=progesterone receptor /DB_XREF=gi:4505766 /UG=Hs.2905 progesterone receptor /FL=gb:M15716.1 gb:AF016381.1 gb:NM_000926.1 NM_000926 progesterone receptor PGR 5241 NM_000926 /// NM_001202474 /// NM_001271161 /// NM_001271162 /// NR_073141 /// NR_073142 /// NR_073143 /// XM_006718858 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from expression pattern /// 0030879 // mammary gland development // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0060748 // tertiary branching involved in mammary gland duct morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208306_x_at NM_021983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021983.2 /DEF=Homo sapiens major histocompatibility complex, class II, DR beta 4 (HLA-DRB4), mRNA. /FEA=mRNA /GEN=HLA-DRB4 /PROD=major histocompatibility complex, class II, DRbeta 4 /DB_XREF=gi:11875206 /UG=Hs.293934 major histocompatibility complex, class II, DR beta 4 /FL=gb:NM_021983.2 NM_021983 Homo sapiens major histocompatibility complex, class II, DR beta 1 (HLA-DRB1), transcript variant 2, mRNA. /// major histocompatibility complex, class II, DR beta 1 HLA-DRB1 /// HLA-DRB1 3123 NM_001243965 /// NM_002124 /// XM_006710243 /// XM_006725752 /// XM_006725860 /// XR_430944 /// XR_430980 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 208307_at NM_005058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005058.1 /DEF=Homo sapiens RNA binding motif protein, Y chromosome, family 1, member A1 (RBMY1A1), mRNA. /FEA=mRNA /GEN=RBMY1A1 /PROD=RNA binding motif protein, Y chromosome, family1, member A1 /DB_XREF=gi:4826973 /UG=Hs.2958 RNA binding motif protein, Y chromosome, family 1, member A1 /FL=gb:NM_005058.1 NM_005058 RNA binding motif protein, Y-linked, family 1, member A1 /// RNA binding motif protein, Y-linked, family 1, member B /// RNA binding motif protein, Y-linked, family 1, member D /// RNA binding motif protein, Y-linked, family 1, member E /// RNA binding motif protein, Y-linked, family 1, member F /// RNA binding motif protein, Y-linked, family 1, member J RBMY1A1 /// RBMY1B /// RBMY1D /// RBMY1E /// RBMY1F /// RBMY1J 5940 /// 159163 /// 378948 /// 378949 /// 378950 /// 378951 NM_001006117 /// NM_001006118 /// NM_001006120 /// NM_001006121 /// NM_001007526 /// NM_005058 /// NM_152585 /// XM_005262511 /// XM_005262512 /// XM_005262513 /// XM_005262514 /// XM_005262515 /// XM_005262516 /// XM_005262517 /// XM_005262574 /// XM_005262575 /// XM_005262576 /// XM_005262577 /// XM_005262583 /// XM_005262584 /// XM_005262585 /// XM_005262586 /// XM_005262587 /// XM_005262588 /// XM_005262589 /// XM_005262590 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0008584 // male gonad development // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 208308_s_at NM_000175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000175.1 /DEF=Homo sapiens glucose phosphate isomerase (GPI), mRNA. /FEA=mRNA /GEN=GPI /PROD=glucose phosphate isomerase /DB_XREF=gi:4504086 /UG=Hs.180532 glucose phosphate isomerase /FL=gb:BC004982.1 gb:K03515.1 gb:NM_000175.1 NM_000175 glucose-6-phosphate isomerase GPI 2821 NM_000175 /// NM_001184722 /// NM_001289789 /// NM_001289790 /// XM_005258763 /// XM_005258764 /// XM_006723148 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007599 // hemostasis // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0019242 // methylglyoxal biosynthetic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046185 // aldehyde catabolic process // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004347 // glucose-6-phosphate isomerase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 208309_s_at NM_006785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006785.1 /DEF=Homo sapiens mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), mRNA. /FEA=mRNA /GEN=MALT1 /PROD=mucosa associated lymphoid tissue lymphomatranslocation gene 1 /DB_XREF=gi:5803077 /UG=Hs.180566 mucosa associated lymphoid tissue lymphoma translocation gene 1 /FL=gb:AF316597.1 gb:AF130356.2 gb:NM_006785.1 NM_006785 mucosa associated lymphoid tissue lymphoma translocation gene 1 MALT1 10892 NM_006785 /// NM_173844 /// XM_005266644 0001923 // B-1 B cell differentiation // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from direct assay /// 0006952 // defense response // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0009620 // response to fungus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051168 // nuclear export // inferred from direct assay /// 0051259 // protein oligomerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0032449 // CBM complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from mutant phenotype /// 0043621 // protein self-association // inferred from physical interaction 208310_s_at NM_007085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007085.1 /DEF=Homo sapiens follistatin-like 1 (FSTL1), mRNA. /FEA=mRNA /GEN=FSTL1 /PROD=follistatin-like 1 /DB_XREF=gi:5901955 /UG=Hs.296267 follistatin-like 1 /FL=gb:D89937.1 gb:NM_007085.1 NM_007085 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) /// CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) CCZ1 /// CCZ1B 51622 /// 221960 NM_015622 /// NM_198097 0030509 // BMP signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement 208311_at NM_004224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004224.1 /DEF=Homo sapiens G protein-coupled receptor 50 (GPR50), mRNA. /FEA=mRNA /GEN=GPR50 /PROD=G protein-coupled receptor 50 /DB_XREF=gi:4758467 /UG=Hs.158329 G protein-coupled receptor 50 /FL=gb:U52219.1 gb:NM_004224.1 NM_004224 G protein-coupled receptor 50 GPR50 9248 NM_004224 /// XM_005274772 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008502 // melatonin receptor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 208312_s_at NM_023013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023013.1 /DEF=Homo sapiens hypothetical protein similar to preferentially expressed antigen of melanoma (LOC65121), mRNA. /FEA=mRNA /GEN=LOC65121 /PROD=hypothetical protein similar to preferentiallyexpressed antigen of melanoma /DB_XREF=gi:12738830 /UG=Hs.296447 hypothetical protein similar to preferentially expressed antigen of melanoma /FL=gb:NM_023013.1 NM_023013 PRAME family member 1 /// PRAME family member 2 PRAMEF1 /// PRAMEF2 65121 /// 65122 NM_001294139 /// NM_023013 /// NM_023014 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0042974 // retinoic acid receptor binding // inferred from electronic annotation 208313_s_at NM_004630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004630.1 /DEF=Homo sapiens zinc finger protein 162 (ZNF162), mRNA. /FEA=mRNA /GEN=ZNF162 /PROD=zinc finger protein 162 /DB_XREF=gi:4759339 /UG=Hs.180677 zinc finger protein 162 /FL=gb:NM_004630.1 gb:D26120.1 NM_004630 splicing factor 1 SF1 7536 NM_001178030 /// NM_001178031 /// NM_004630 /// NM_201995 /// NM_201997 /// NM_201998 /// NR_033649 /// NR_033650 /// XM_006718681 /// XM_006718682 /// XM_006718683 /// XM_006718684 /// XM_006718685 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0022402 // cell cycle process // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005840 // ribosome // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208314_at NM_006583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006583.1 /DEF=Homo sapiens retinal pigment epithelium-derived rhodopsin homolog (RRH), mRNA. /FEA=mRNA /GEN=RRH /PROD=retinal pigment epithelium-derived rhodopsinhomolog /DB_XREF=gi:5730018 /UG=Hs.158338 retinal pigment epithelium-derived rhodopsin homolog /FL=gb:AF012270.1 gb:NM_006583.1 NM_006583 retinal pigment epithelium-derived rhodopsin homolog RRH 10692 NM_006583 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0009881 // photoreceptor activity // inferred from electronic annotation 208315_x_at NM_003300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003300.1 /DEF=Homo sapiens TNF receptor-associated factor 3 (TRAF3), mRNA. /FEA=mRNA /GEN=TRAF3 /PROD=TNF receptor-associated factor 3 /DB_XREF=gi:4507678 /UG=Hs.297660 TNF receptor-associated factor 3 /FL=gb:NM_003300.1 gb:U21092.1 NM_003300 TNF receptor-associated factor 3 TRAF3 7187 NM_001199427 /// NM_003300 /// NM_145725 /// NM_145726 /// XM_006720244 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030162 // regulation of proteolysis // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032648 // regulation of interferon-beta production // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050688 // regulation of defense response to virus // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208316_s_at M88162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M88162.2 /DEF=Homo sapiens Lowe oculocerebrorenal syndrome protein (OCRL) mRNA, complete cds. /FEA=mRNA /GEN=OCRL /PROD=Lowe oculocerebrorenal syndrome protein /DB_XREF=gi:13249984 /UG=Hs.181060 oculocerebrorenal syndrome of Lowe /FL=gb:M88162.2 gb:NM_001587.2 M88162 oculocerebrorenal syndrome of Lowe OCRL 4952 NM_000276 /// NM_001587 /// XM_005262421 /// XM_005262422 /// XM_006724760 /// XM_006724761 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001750 // photoreceptor outer segment // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // traceable author statement /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0052745 // inositol phosphate phosphatase activity // non-traceable author statement 208317_at NM_005108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005108.1 /DEF=Homo sapiens xylulokinase (H. influenzae) homolog (XYLB), mRNA. /FEA=mRNA /GEN=XYLB /PROD=xylulokinase (H. influenzae) homolog /DB_XREF=gi:4827059 /UG=Hs.137580 xylulokinase (H. influenzae) homolog /FL=gb:AB015046.1 gb:NM_005108.1 NM_005108 xylulokinase homolog (H. influenzae) XYLB 9942 NM_005108 /// XM_006713448 /// XM_006713449 /// XM_006713450 /// XR_245171 0005975 // carbohydrate metabolic process // traceable author statement /// 0005997 // xylulose metabolic process // inferred from direct assay /// 0005998 // xylulose catabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042732 // D-xylose metabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004856 // xylulokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 208318_s_at NM_005108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005108.1 /DEF=Homo sapiens xylulokinase (H. influenzae) homolog (XYLB), mRNA. /FEA=mRNA /GEN=XYLB /PROD=xylulokinase (H. influenzae) homolog /DB_XREF=gi:4827059 /UG=Hs.137580 xylulokinase (H. influenzae) homolog /FL=gb:AB015046.1 gb:NM_005108.1 NM_005108 xylulokinase homolog (H. influenzae) XYLB 9942 NM_005108 /// XM_006713448 /// XM_006713449 /// XM_006713450 /// XR_245171 0005975 // carbohydrate metabolic process // traceable author statement /// 0005997 // xylulose metabolic process // inferred from direct assay /// 0005998 // xylulose catabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042732 // D-xylose metabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004856 // xylulokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 208319_s_at NM_006743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006743.1 /DEF=Homo sapiens RNA binding motif protein 3 (RBM3), mRNA. /FEA=mRNA /GEN=RBM3 /PROD=RNA binding motif protein 3 /DB_XREF=gi:5803136 /UG=Hs.301404 RNA binding motif protein 3 /FL=gb:NM_006743.1 gb:U28686.1 NM_006743 RNA binding motif (RNP1, RRM) protein 3 RBM3 5935 NM_001017430 /// NM_001017431 /// NM_006743 0006396 // RNA processing // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0015934 // large ribosomal subunit // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043023 // ribosomal large subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208320_at NM_004276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004276.1 /DEF=Homo sapiens calcium binding protein 1 (calbrain) (CABP1), mRNA. /FEA=mRNA /GEN=CABP1 /PROD=calcium binding protein 1 (calbrain) /DB_XREF=gi:4758511 /UG=Hs.301423 calcium binding protein 1 (calbrain) /FL=gb:NM_004276.1 NM_004276 calcium binding protein 1 CABP1 9478 NM_001033677 /// NM_004276 /// NM_031205 /// XM_005253994 0010651 // negative regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 208321_s_at NM_004276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004276.1 /DEF=Homo sapiens calcium binding protein 1 (calbrain) (CABP1), mRNA. /FEA=mRNA /GEN=CABP1 /PROD=calcium binding protein 1 (calbrain) /DB_XREF=gi:4758511 /UG=Hs.301423 calcium binding protein 1 (calbrain) /FL=gb:NM_004276.1 NM_004276 calcium binding protein 1 CABP1 9478 NM_001033677 /// NM_004276 /// NM_031205 /// XM_005253994 0010651 // negative regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 208322_s_at NM_003033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003033.1 /DEF=Homo sapiens sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase) (SIAT4A), mRNA. /FEA=mRNA /GEN=SIAT4A /PROD=sialyltransferase 4A (beta-galactosidasealpha-2,3-sialytransferase) /DB_XREF=gi:4506950 /UG=Hs.301698 sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase) /FL=gb:L13972.1 gb:NM_003033.1 gb:L29555.1 NM_003033 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ST3GAL1 6482 NM_003033 /// NM_173344 /// XM_005251023 /// XM_005251024 /// XM_005251025 /// XM_006716617 0005975 // carbohydrate metabolic process // traceable author statement /// 0006054 // N-acetylneuraminate metabolic process // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from sequence or structural similarity /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097503 // sialylation // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from sequence or structural similarity /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 208323_s_at NM_004306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004306.1 /DEF=Homo sapiens annexin A13 (ANXA13), mRNA. /FEA=mRNA /GEN=ANXA13 /PROD=annexin A13 /DB_XREF=gi:4757753 /UG=Hs.181107 annexin A13 /FL=gb:NM_004306.1 NM_004306 annexin A13 ANXA13 312 NM_001003954 /// NM_004306 0030154 // cell differentiation // non-traceable author statement /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from sequence or structural similarity /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 1901611 // phosphatidylglycerol binding // inferred from direct assay 208324_at NM_006738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006738.1 /DEF=Homo sapiens lymphoid blast crisis oncogene (LBC), mRNA. /FEA=mRNA /GEN=LBC /PROD=lymphoid blast crisis oncogene /DB_XREF=gi:5803057 /UG=Hs.301946 lymphoid blast crisis oncogene /FL=gb:U03634.1 gb:NM_006738.1 NM_006738 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 208325_s_at NM_006738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006738.1 /DEF=Homo sapiens lymphoid blast crisis oncogene (LBC), mRNA. /FEA=mRNA /GEN=LBC /PROD=lymphoid blast crisis oncogene /DB_XREF=gi:5803057 /UG=Hs.301946 lymphoid blast crisis oncogene /FL=gb:U03634.1 gb:NM_006738.1 NM_006738 A kinase (PRKA) anchor protein 13 AKAP13 11214 NM_001270546 /// NM_006738 /// NM_007200 /// NM_144767 /// XM_005254839 /// XM_005254840 /// XM_005254841 /// XM_005254842 /// XM_005254843 /// XM_005254844 /// XM_005254845 /// XM_005254846 /// XM_005254847 /// XM_005254848 /// XM_005254849 /// XM_005254850 /// XM_005254851 /// XM_005254852 /// XM_005254853 /// XM_005254854 /// XM_005254855 /// XM_005254856 /// XM_006720376 /// XM_006720377 /// XM_006720378 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 208327_at NM_000766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000766.2 /DEF=Homo sapiens cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13 (CYP2A13), mRNA. /FEA=mRNA /GEN=CYP2A13 /PROD=cytochrome P450, subfamily IIA(phenobarbital-inducible), polypeptide 13 /DB_XREF=gi:13699808 /UG=Hs.181973 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13 /FL=gb:AF209774.1 gb:NM_000766.2 NM_000766 cytochrome P450, family 2, subfamily A, polypeptide 13 CYP2A13 1553 NM_000766 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 208328_s_at NM_005587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005587.1 /DEF=Homo sapiens MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) (MEF2A), mRNA. /FEA=mRNA /GEN=MEF2A /PROD=MADS box transcription enhancer factor 2,polypeptide A (myocyte enhancer factor 2A) /DB_XREF=gi:5031906 /UG=Hs.182280 MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) /FL=gb:NM_005587.1 NM_005587 myocyte enhancer factor 2A MEF2A 4205 NM_001130926 /// NM_001130927 /// NM_001130928 /// NM_001171894 /// NM_005587 /// XM_005254914 /// XM_005254915 /// XM_005254916 /// XM_006720509 /// XM_006720510 /// XM_006720511 /// XM_006720512 /// XM_006720513 /// XM_006720514 /// XM_006720515 /// XM_006720516 /// XM_006720517 /// XM_006720518 /// XM_006720519 /// XM_006720520 /// XM_006720521 0000002 // mitochondrial genome maintenance // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from direct assay /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003138 // primary heart field specification // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003185 // sinoatrial valve morphogenesis // inferred from electronic annotation /// 0003211 // cardiac ventricle formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048311 // mitochondrion distribution // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0055005 // ventricular cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0061333 // renal tubule morphogenesis // inferred from electronic annotation /// 0061337 // cardiac conduction // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from electronic annotation /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from electronic annotation /// 0072160 // nephron tubule epithelial cell differentiation // inferred from electronic annotation /// 0090073 // positive regulation of protein homodimerization activity // inferred from electronic annotation /// 2000111 // positive regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 208329_at NM_021635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021635.1 /DEF=Homo sapiens UC28 protein (UC28), mRNA. /FEA=mRNA /GEN=UC28 /PROD=UC28 protein /DB_XREF=gi:11056009 /UG=Hs.302016 UC28 protein /FL=gb:AF189269.1 gb:NM_021635.1 NM_021635 prostate and breast cancer overexpressed 1 PBOV1 59351 NM_021635 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 208330_at NM_021926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021926.1 /DEF=Homo sapiens aristaless-like homeobox 4 (ALX4), mRNA. /FEA=mRNA /GEN=ALX4 /PROD=aristaless-like homeobox 4 /DB_XREF=gi:11496266 /UG=Hs.302020 aristaless-like homeobox 4 /FL=gb:AF294629.1 gb:NM_021926.1 NM_021926 ALX homeobox 4 ALX4 60529 NM_021926 /// XR_242817 0001501 // skeletal system development // non-traceable author statement /// 0001942 // hair follicle development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 208331_at NM_004678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004678.1 /DEF=Homo sapiens Testis-specific basic protein on Y, 2 (BPY2), mRNA. /FEA=mRNA /GEN=BPY2 /PROD=testis-specific basic protein on Y, 2 /DB_XREF=gi:4757863 /UG=Hs.158342 Testis-specific basic protein on Y, 2 /FL=gb:AF000980.1 gb:NM_004678.1 NM_004678 basic charge, Y-linked, 2 BPY2 9083 NM_004678 0007283 // spermatogenesis // inferred from mutant phenotype /// 0007338 // single fertilization // traceable author statement 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032399 // HECT domain binding // inferred from physical interaction 208332_at NM_004676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004676.1 /DEF=Homo sapiens Testis-specific PTP-BL-related protein on Y (PRY), mRNA. /FEA=mRNA /GEN=PRY /PROD=Testis-specific PTP-BL-related protein on Y /DB_XREF=gi:4758961 /UG=Hs.158343 Testis-specific PTP-BL-related protein on Y /FL=gb:AF000988.1 gb:NM_004676.1 NM_004676 PTPN13-like protein, Y-linked-like /// PTPN13-like, Y-linked /// PTPN13-like, Y-linked 2 LOC100509646 /// PRY /// PRY2 9081 /// 442862 /// 100509646 NM_001002758 /// NM_004676 /// XM_003120335 208333_at NM_022363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022363.1 /DEF=Homo sapiens LIM homeobox protein 5 (LHX5), mRNA. /FEA=mRNA /GEN=LHX5 /PROD=LIM homeobox protein 5 /DB_XREF=gi:11641282 /UG=Hs.302029 LIM homeobox protein 5 /FL=gb:AF291181.1 gb:NM_022363.1 NM_022363 LIM homeobox 5 LHX5 64211 NM_022363 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021937 // cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208334_at NM_022569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022569.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase 4 (NDST4), mRNA. /FEA=mRNA /GEN=NDST4 /PROD=N-deacetylaseN-sulfotransferase 4 /DB_XREF=gi:12007649 /UG=Hs.302033 N-deacetylaseN-sulfotransferase 4 /FL=gb:AB036429.1 gb:NM_022569.1 NM_022569 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 NDST4 64579 NM_022569 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030210 // heparin biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 208335_s_at NM_002036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002036.1 /DEF=Homo sapiens Duffy blood group (FY), mRNA. /FEA=mRNA /GEN=FY /PROD=Duffy blood group /DB_XREF=gi:4503818 /UG=Hs.183 Duffy blood group /FL=gb:U01839.1 gb:NM_002036.1 NM_002036 atypical chemokine receptor 1 (Duffy blood group) ACKR1 2532 NM_001122951 /// NM_002036 0006952 // defense response // non-traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032642 // regulation of chemokine production // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // non-traceable author statement /// 0019956 // chemokine binding // inferred from electronic annotation /// 0019957 // C-C chemokine binding // inferred from physical interaction 208336_s_at NM_004868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004868.1 /DEF=Homo sapiens glycoprotein, synaptic 2 (GPSN2), mRNA. /FEA=mRNA /GEN=GPSN2 /PROD=glycoprotein, synaptic 2 /DB_XREF=gi:4759061 /UG=Hs.306122 glycoprotein, synaptic 2 /FL=gb:AF038959.1 gb:NM_004868.1 NM_004868 trans-2,3-enoyl-CoA reductase TECR 9524 NM_004868 /// NM_138501 /// NR_038103 /// NR_038104 /// XM_006722945 /// XM_006722946 /// XM_006722947 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030497 // fatty acid elongation // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation 208337_s_at NM_003822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003822.1 /DEF=Homo sapiens nuclear receptor subfamily 5, group A, member 2 (NR5A2), mRNA. /FEA=mRNA /GEN=NR5A2 /PROD=nuclear receptor subfamily 5, group A, member 2 /DB_XREF=gi:4504342 /UG=Hs.183123 nuclear receptor subfamily 5, group A, member 2 /FL=gb:U80251.1 gb:NM_003822.1 gb:AF146343.1 NM_003822 nuclear receptor subfamily 5, group A, member 2 NR5A2 2494 NM_001276464 /// NM_003822 /// NM_205860 /// XM_005245061 /// XM_005245062 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031018 // endocrine pancreas development // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208338_at NM_002559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002559.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), mRNA. /FEA=mRNA /GEN=P2RX3 /PROD=purinergic receptor P2X, ligand-gated ionchannel, 3 /DB_XREF=gi:4505546 /UG=Hs.127430 purinergic receptor P2X, ligand-gated ion channel, 3 /FL=gb:NM_002559.1 gb:AB016608.1 NM_002559 purinergic receptor P2X, ligand-gated ion channel, 3 P2RX3 5024 NM_002559 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0009266 // response to temperature stimulus // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // not recorded /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 208339_at NM_004677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004677.1 /DEF=Homo sapiens Testis-specific XK-related protein on Y (XKRY), mRNA. /FEA=mRNA /GEN=XKRY /PROD=Testis-specific XK-related protein on Y /DB_XREF=gi:4759329 /UG=Hs.158346 Testis-specific XK-related protein on Y /FL=gb:AF000997.1 gb:NM_004677.1 NM_004677 XK, Kell blood group complex subunit-related, Y-linked /// XK, Kell blood group complex subunit-related, Y-linked 2 XKRY /// XKRY2 9082 /// 353515 NM_001002906 /// NM_004677 0007338 // single fertilization // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 208340_at NM_003723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003723.1 /DEF=Homo sapiens caspase 13, apoptosis-related cysteine protease (CASP13), mRNA. /FEA=mRNA /GEN=CASP13 /PROD=caspase 13 /DB_XREF=gi:4502570 /UG=Hs.137587 caspase 13, apoptosis-related cysteine protease /FL=gb:AF078533.1 gb:NM_003723.1 NM_003723 caspase 4, apoptosis-related cysteine peptidase pseudogene LOC643733 643733 NR_034078 /// NR_034079 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // /// 0070269 // pyroptosis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // /// 0072557 // IPAF inflammasome complex // /// 0072559 // NLRP3 inflammasome complex // /// 0097169 // AIM2 inflammasome complex // 0004197 // cysteine-type endopeptidase activity // /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 208341_x_at NM_022646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022646.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 4, mRNA. /FEA=mRNA /GEN=CSH2 /PROD=chorionic somatomammotropin hormone 2, isoform4 /DB_XREF=gi:12408695 /UG=Hs.306155 chorionic somatomammotropin hormone 2 /FL=gb:NM_022646.1 NM_022646 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 CSH1 /// CSH2 1442 /// 1443 NM_001317 /// NM_020991 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 0007165 // signal transduction // non-traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208342_x_at NM_022645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022645.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 3, mRNA. /FEA=mRNA /GEN=CSH2 /PROD=chorionic somatomammotropin hormone 2, isoform 3precursor /DB_XREF=gi:12408693 /UG=Hs.306155 chorionic somatomammotropin hormone 2 /FL=gb:NM_022645.1 NM_022645 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 CSH1 /// CSH2 1442 /// 1443 NM_001317 /// NM_020991 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 0007165 // signal transduction // non-traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208343_s_at AF146343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF146343.1 /DEF=Homo sapiens CYP7A promoter binding factor (CPF) mRNA, complete cds. /FEA=mRNA /GEN=CPF /PROD=CYP7A promoter binding factor /DB_XREF=gi:5002241 /UG=Hs.183123 nuclear receptor subfamily 5, group A, member 2 /FL=gb:U80251.1 gb:NM_003822.1 gb:AF146343.1 AF146343 nuclear receptor subfamily 5, group A, member 2 NR5A2 2494 NM_001276464 /// NM_003822 /// NM_205860 /// XM_005245061 /// XM_005245062 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031018 // endocrine pancreas development // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208344_x_at NM_006900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006900.2 /DEF=Homo sapiens interferon, alpha 13 (IFNA13), mRNA. /FEA=mRNA /GEN=IFNA13 /PROD=interferon, alpha 13 /DB_XREF=gi:13128965 /UG=Hs.306172 interferon, alpha 13 /FL=gb:NM_006900.2 NM_006900 interferon, alpha 1 /// interferon, alpha 13 IFNA1 /// IFNA13 3439 /// 3447 NM_006900 /// NM_024013 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // not recorded 208345_s_at NM_002699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002699.1 /DEF=Homo sapiens POU domain, class 3, transcription factor 1 (POU3F1), mRNA. /FEA=mRNA /GEN=POU3F1 /PROD=POU domain, class 3, transcription factor 1 /DB_XREF=gi:4505960 /UG=Hs.1837 POU domain, class 3, transcription factor 1 /FL=gb:NM_002699.1 NM_002699 POU class 3 homeobox 1 POU3F1 5453 NM_002699 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008366 // axon ensheathment // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 208346_at NM_006692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006692.1 /DEF=Homo sapiens DNA-binding protein amplifying expression of surfactant protein B (SPBPBP), mRNA. /FEA=mRNA /GEN=SPBPBP /PROD=DNA-binding protein amplifying expression ofsurfactant protein B /DB_XREF=gi:5730060 /UG=Hs.3134 DNA-binding protein amplifying expression of surfactant protein B /FL=gb:NM_006692.1 gb:L10403.1 NM_006692 pro-platelet basic protein pseudogene 2 PPBPP2 10895 NM_006692 /// NR_026769 208347_at NM_021024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021024.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 17-like 1 (HMG17L1), mRNA. /FEA=mRNA /GEN=HMG17L1 /PROD=high-mobility group (nonhistone chromosomal)protein 17-like 1 /DB_XREF=gi:11999175 /UG=Hs.158349 high-mobility group (nonhistone chromosomal) protein 17-like 1 /FL=gb:NM_021024.1 NM_021024 /// high mobility group nucleosomal binding domain 2 pseudogene 9 HMGN2P9 /// HMGN2P9 208348_s_at NM_004351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004351.1 /DEF=Homo sapiens Cas-Br-M (murine) ectropic retroviral transforming sequence b (CBLB), mRNA. /FEA=mRNA /GEN=CBLB /PROD=Cas-Br-M (murine) ectropic retroviraltransforming sequence b /DB_XREF=gi:4757919 /UG=Hs.3144 Cas-Br-M (murine) ectropic retroviral transforming sequence b /FL=gb:NM_004351.1 gb:U26712.1 NM_004351 Cbl proto-oncogene B, E3 ubiquitin protein ligase CBLB 868 NM_170662 /// XM_005247852 /// XM_005247853 /// XM_006713796 /// XM_006713797 /// XR_427384 /// XR_427385 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0023051 // regulation of signaling // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208349_at NM_007332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007332.1 /DEF=Homo sapiens ankyrin-like with transmembrane domains 1 (ANKTM1), mRNA. /FEA=mRNA /GEN=ANKTM1 /PROD=ankyrin-like protein 1 /DB_XREF=gi:6601589 /UG=Hs.137674 ankyrin-like with transmembrane domains 1 /FL=gb:NM_007332.1 NM_007332 transient receptor potential cation channel, subfamily A, member 1 TRPA1 8989 NM_007332 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050955 // thermoception // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050968 // detection of chemical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015267 // channel activity // traceable author statement 208350_at NM_001890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001890.1 /DEF=Homo sapiens casein, alpha (CSN1), mRNA. /FEA=mRNA /GEN=CSN1 /PROD=casein, alpha /DB_XREF=gi:4503084 /UG=Hs.3155 casein, alpha /FL=gb:NM_001890.1 gb:U23157.1 NM_001890 casein alpha s1 CSN1S1 1446 NM_001025104 /// NM_001890 /// XM_006714089 /// XM_006714090 /// XM_006714091 0006810 // transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 208351_s_at NM_002745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002745.1 /DEF=Homo sapiens mitogen-activated protein kinase 1 (MAPK1), mRNA. /FEA=mRNA /GEN=MAPK1 /PROD=mitogen-activated protein kinase 1 /DB_XREF=gi:4506086 /UG=Hs.324473 mitogen-activated protein kinase 1 /FL=gb:NM_002745.1 NM_002745 mitogen-activated protein kinase 1 MAPK1 5594 NM_002745 /// NM_138957 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000189 // MAPK import into nucleus // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019858 // cytosine metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0072584 // caveolin-mediated endocytosis // traceable author statement /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005901 // caveola // traceable author statement /// 0005925 // focal adhesion // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 208352_x_at NM_020479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020479.1 /DEF=Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 6, mRNA. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin 1, isoform 6 /DB_XREF=gi:10947045 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_020479.1 NM_020479 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 208353_x_at NM_020480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020480.1 /DEF=Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 7, mRNA. /FEA=mRNA /GEN=ANK1 /PROD=ankyrin 1, isoform 7 /DB_XREF=gi:10947047 /UG=Hs.183805 ankyrin 1, erythrocytic /FL=gb:NM_020480.1 NM_020480 ankyrin 1, erythrocytic ANK1 286 NM_000037 /// NM_001142445 /// NM_001142446 /// NM_020475 /// NM_020476 /// NM_020477 /// NM_020478 /// NM_020479 /// NM_020480 /// NM_020481 /// XM_005273476 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0045199 // maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019899 // enzyme binding // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from physical interaction /// 0030507 // spectrin binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from physical interaction 208354_s_at NM_000339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000339.1 /DEF=Homo sapiens solute carrier family 12 (sodiumchloride transporters), member 3 (SLC12A3), mRNA. /FEA=mRNA /GEN=SLC12A3 /PROD=solute carrier family 12 (sodiumchloridetransporters), member 3 /DB_XREF=gi:4506976 /UG=Hs.158462 solute carrier family 12 (sodiumchloride transporters), member 3 /FL=gb:U44128.1 gb:NM_000339.1 NM_000339 solute carrier family 12 (sodium/chloride transporter), member 3 SLC12A3 6559 NM_000339 /// NM_001126107 /// NM_001126108 /// XM_005256119 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006821 // chloride transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015378 // sodium:chloride symporter activity // traceable author statement 208356_x_at NM_022642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022642.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 4, mRNA. /FEA=mRNA /GEN=CSH1 /PROD=chorionic somatomammotropin hormone 1, isoform4 /DB_XREF=gi:12408688 /UG=Hs.324928 chorionic somatomammotropin hormone 1 (placental lactogen) /FL=gb:NM_022642.1 NM_022642 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSHL1 /// GH1 1442 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208357_x_at NM_022641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022641.1 /DEF=Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 3, mRNA. /FEA=mRNA /GEN=CSH1 /PROD=chorionic somatomammotropin hormone 1, isoform 3precursor /DB_XREF=gi:12408686 /UG=Hs.324928 chorionic somatomammotropin hormone 1 (placental lactogen) /FL=gb:NM_022641.1 NM_022641 chorionic somatomammotropin hormone 1 (placental lactogen) CSH1 1442 NM_001317 /// NM_022640 /// NM_022641 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208358_s_at NM_003360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003360.1 /DEF=Homo sapiens UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase) (UGT8), mRNA. /FEA=mRNA /GEN=UGT8 /PROD=UDP glycosyltransferase 8 (UDP-galactoseceramide galactosyltransferase) /DB_XREF=gi:4507826 /UG=Hs.158540 UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase) /FL=gb:U62899.1 gb:NM_003360.1 NM_003360 UDP glycosyltransferase 8 UGT8 7368 NM_001128174 /// NM_003360 /// XM_006714302 /// XM_006714303 0002175 // protein localization to paranode region of axon // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006682 // galactosylceramide biosynthetic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003851 // 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity // inferred from electronic annotation /// 0008489 // UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 208359_s_at NM_004981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004981.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), mRNA. /FEA=mRNA /GEN=KCNJ4 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 4 /DB_XREF=gi:4826797 /UG=Hs.32505 potassium inwardly-rectifying channel, subfamily J, member 4 /FL=gb:NM_004981.1 gb:U07364.1 NM_004981 potassium inwardly-rectifying channel, subfamily J, member 4 KCNJ4 3761 NM_004981 /// NM_152868 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 208360_s_at NM_015870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015870.1 /DEF=Homo sapiens endogenous retrovirus H D1 leader regionintegrase-derived ORF1, ORF2, and putative envelope protein (HSU88895), mRNA. /FEA=mRNA /GEN=HSU88895 /PROD=endogenous retrovirus H D1 leaderregionintegrase-derived ORF1, ORF2, and putative envelopeprotein /DB_XREF=gi:7705540 /UG=Hs.326539 endogenous retrovirus H D1 leader regionintegrase-derived ORF1, ORF2, and putative envelope protein /FL=gb:NM_015870.1 NM_015870 endogenous retrovirus group H, member 4 ERVH-4 51359 0006508 // proteolysis // inferred from electronic annotation 0016021 // integral component of membrane // non-traceable author statement /// 0019031 // viral envelope // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation 208361_s_at NM_001722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001722.1 /DEF=Homo sapiens BN51 (BHK21) temperature sensitivity complementing (BN51T), mRNA. /FEA=mRNA /GEN=BN51T /PROD=temperature sensitivity complementing BHK21 /DB_XREF=gi:4502436 /UG=Hs.1276 BN51 (BHK21) temperature sensitivity complementing /FL=gb:M17754.1 gb:NM_001722.1 NM_001722 polymerase (RNA) III (DNA directed) polypeptide D, 44kDa POLR3D 661 NM_001722 0002376 // immune system process // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation 208363_s_at NM_001566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001566.1 /DEF=Homo sapiens inositol polyphosphate-4-phosphatase, type I, 107kD (INPP4A), transcript variant b, mRNA. /FEA=mRNA /GEN=INPP4A /PROD=inositol polyphosphate-4-phosphatase, type 1,isoform b /DB_XREF=gi:4504704 /UG=Hs.32944 inositol polyphosphate-4-phosphatase, type I, 107kD /FL=gb:U96919.1 gb:NM_001566.1 NM_001566 inositol polyphosphate-4-phosphatase, type I, 107kDa INPP4A 3631 NM_001134224 /// NM_001134225 /// NM_001566 /// NM_004027 /// XM_006712499 /// XM_006712500 /// XM_006712501 /// XM_006712502 /// XM_006712503 /// XM_006712504 /// XM_006712505 /// XM_006712506 /// XM_006712507 /// XM_006712508 /// XM_006712509 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016316 // phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034597 // phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity // inferred from electronic annotation 208364_at NM_001566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001566.1 /DEF=Homo sapiens inositol polyphosphate-4-phosphatase, type I, 107kD (INPP4A), transcript variant b, mRNA. /FEA=mRNA /GEN=INPP4A /PROD=inositol polyphosphate-4-phosphatase, type 1,isoform b /DB_XREF=gi:4504704 /UG=Hs.32944 inositol polyphosphate-4-phosphatase, type I, 107kD /FL=gb:U96919.1 gb:NM_001566.1 NM_001566 inositol polyphosphate-4-phosphatase, type I, 107kDa INPP4A 3631 NM_001134224 /// NM_001134225 /// NM_001566 /// NM_004027 /// XM_006712499 /// XM_006712500 /// XM_006712501 /// XM_006712502 /// XM_006712503 /// XM_006712504 /// XM_006712505 /// XM_006712506 /// XM_006712507 /// XM_006712508 /// XM_006712509 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0016316 // phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034597 // phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity // inferred from electronic annotation 208365_s_at NM_005307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005307.1 /DEF=Homo sapiens G protein-coupled receptor kinase 2 (Drosophila)-like (GPRK2L), mRNA. /FEA=mRNA /GEN=GPRK2L /PROD=G protein-coupled receptor kinase 2(Drosophila)-like /DB_XREF=gi:4885346 /UG=Hs.32959 G protein-coupled receptor kinase 2 (Drosophila)-like /FL=gb:NM_005307.1 NM_005307 G protein-coupled receptor kinase 4 GRK4 2868 NM_001004056 /// NM_001004057 /// NM_005307 /// NM_182982 /// XM_005247957 /// XM_005247959 /// XM_005247960 /// XM_005247961 /// XM_005247962 /// XM_005247963 /// XM_006713879 /// XM_006713880 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050254 // rhodopsin kinase activity // inferred from electronic annotation 208366_at NM_014522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014522.1 /DEF=Homo sapiens protocadherin 11 (PCDH11), mRNA. /FEA=mRNA /GEN=PCDH11 /PROD=protocadherin 11 /DB_XREF=gi:7657442 /UG=Hs.159156 protocadherin 11 /FL=gb:AB026187.1 gb:NM_014522.1 NM_014522 protocadherin 11 X-linked PCDH11X 27328 NM_001168360 /// NM_001168361 /// NM_001168362 /// NM_001168363 /// NM_014522 /// NM_032967 /// NM_032968 /// NM_032969 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 208367_x_at NM_000776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000776.1 /DEF=Homo sapiens cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 (CYP3A3), mRNA. /FEA=mRNA /GEN=CYP3A3 /PROD=cytochrome P450, subfamily IIIA (niphedipineoxidase), polypeptide 3 /DB_XREF=gi:4503228 /UG=Hs.329704 cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 /FL=gb:M13785.1 gb:D00003.1 gb:NM_000776.1 NM_000776 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A4 1576 NM_001202855 /// NM_001202856 /// NM_001202857 /// NM_017460 0006629 // lipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0008209 // androgen metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0036378 // calcitriol biosynthetic process from calciol // inferred from direct assay /// 0042359 // vitamin D metabolic process // inferred by curator /// 0042737 // drug catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005496 // steroid binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from direct assay /// 0033780 // taurochenodeoxycholate 6alpha-hydroxylase activity // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047638 // albendazole monooxygenase activity // inferred from electronic annotation /// 0050591 // quinine 3-monooxygenase activity // inferred from electronic annotation /// 0050649 // testosterone 6-beta-hydroxylase activity // inferred from mutant phenotype /// 0070576 // vitamin D 24-hydroxylase activity // inferred from direct assay 208368_s_at NM_000059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000059.1 /DEF=Homo sapiens breast cancer 2, early onset (BRCA2), mRNA. /FEA=mRNA /GEN=BRCA2 /PROD=breast cancer 2, early onset /DB_XREF=gi:4502450 /UG=Hs.34012 breast cancer 2, early onset /FL=gb:U43746.1 gb:NM_000059.1 NM_000059 breast cancer 2, early onset BRCA2 675 NM_000059 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000910 // cytokinesis // inferred from direct assay /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043009 // chordate embryonic development // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0048478 // replication fork protection // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0033593 // BRCA2-MAGE-D1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010484 // H3 histone acetyltransferase activity // inferred from direct assay /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0043015 // gamma-tubulin binding // inferred from physical interaction 208369_s_at NM_013976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013976.1 /DEF=Homo sapiens glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA. /FEA=mRNA /GEN=GCDH /PROD=glutaryl-Coenzyme A dehydrogenase isoform b /DB_XREF=gi:7669493 /UG=Hs.184141 glutaryl-Coenzyme A dehydrogenase /FL=gb:NM_013976.1 NM_013976 glutaryl-CoA dehydrogenase GCDH 2639 NM_000159 /// NM_013976 /// NR_102316 /// NR_102317 /// XM_006722720 /// XM_006722721 0006554 // lysine catabolic process // traceable author statement /// 0006568 // tryptophan metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004361 // glutaryl-CoA dehydrogenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 208370_s_at NM_004414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004414.2 /DEF=Homo sapiens Down syndrome critical region gene 1 (DSCR1), mRNA. /FEA=mRNA /GEN=DSCR1 /PROD=Down syndrome critical region protein 1 /DB_XREF=gi:7657042 /UG=Hs.184222 Down syndrome critical region gene 1 /FL=gb:U28833.2 gb:NM_004414.2 NM_004414 regulator of calcineurin 1 RCAN1 1827 NM_001285389 /// NM_001285391 /// NM_001285392 /// NM_001285393 /// NM_004414 /// NM_203417 /// NM_203418 /// XM_005260929 /// XM_005260930 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 208371_s_at NM_002931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002931.2 /DEF=Homo sapiens ring finger protein 1 (RING1), mRNA. /FEA=mRNA /GEN=RING1 /PROD=ring finger protein 1 /DB_XREF=gi:11863157 /UG=Hs.35384 ring finger protein 1 /FL=gb:NM_002931.2 NM_002931 ring finger protein 1 RING1 6015 NM_002931 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016568 // chromatin modification // non-traceable author statement /// 0016574 // histone ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208372_s_at AF134379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF134379.1 /DEF=Homo sapiens LIM domain kinase 1 splice variant (LIMK1) mRNA, complete cds. /FEA=mRNA /GEN=LIMK1 /PROD=LIM domain kinase 1 splice variant /DB_XREF=gi:4587498 /UG=Hs.36566 LIM domain kinase 1 /FL=gb:AF134379.1 gb:NM_016735.1 AF134379 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208373_s_at NM_004154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004154.1 /DEF=Homo sapiens pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2RY6), mRNA. /FEA=mRNA /GEN=P2RY6 /PROD=pyrimidinergic receptor P2Y, G-protein coupled,6 /DB_XREF=gi:4758863 /UG=Hs.16362 pyrimidinergic receptor P2Y, G-protein coupled, 6 /FL=gb:AF007892.1 gb:NM_004154.1 NM_004154 pyrimidinergic receptor P2Y, G-protein coupled, 6 P2RY6 5031 NM_001277204 /// NM_001277205 /// NM_001277206 /// NM_001277207 /// NM_001277208 /// NM_004154 /// NM_176796 /// NM_176797 /// NM_176798 /// XM_005274022 /// XM_005274023 /// XM_006718571 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation /// 0045029 // UDP-activated nucleotide receptor activity // inferred from electronic annotation 208374_s_at NM_006135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006135.1 /DEF=Homo sapiens capping protein (actin filament) muscle Z-line, alpha 1 (CAPZA1), mRNA. /FEA=mRNA /GEN=CAPZA1 /PROD=F-actin capping protein alpha-1 subunit /DB_XREF=gi:5453596 /UG=Hs.184270 capping protein (actin filament) muscle Z-line, alpha 1 /FL=gb:U56637.1 gb:NM_006135.1 NM_006135 capping protein (actin filament) muscle Z-line, alpha 1 CAPZA1 829 NM_006135 0006461 // protein complex assembly // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208375_at NM_024013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024013.1 /DEF=Homo sapiens interferon, alpha 1 (IFNA1), mRNA. /FEA=mRNA /GEN=IFNA1 /PROD=interferon, alpha 1 /DB_XREF=gi:13128949 /UG=Hs.37026 interferon, alpha 1 /FL=gb:NM_024013.1 NM_024013 interferon, alpha 1 IFNA1 3439 NM_024013 0002250 // adaptive immune response // /// 0002286 // T cell activation involved in immune response // /// 0002323 // natural killer cell activation involved in immune response // /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // /// 0042100 // B cell proliferation // /// 0043330 // response to exogenous dsRNA // /// 0045087 // innate immune response // /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // /// 0005132 // type I interferon receptor binding // traceable author statement 208376_at NM_005508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005508.1 /DEF=Homo sapiens chemokine (C-C motif) receptor 4 (CCR4), mRNA. /FEA=mRNA /GEN=CCR4 /PROD=chemokine (C-C motif) receptor 4 /DB_XREF=gi:5031626 /UG=Hs.184926 chemokine (C-C motif) receptor 4 /FL=gb:NM_005508.1 NM_005508 chemokine (C-C motif) receptor 4 CCR4 1233 NM_005508 0001764 // neuron migration // inferred from electronic annotation /// 0002507 // tolerance induction // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 208377_s_at NM_005183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005183.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 1F subunit (CACNA1F), mRNA. /FEA=mRNA /GEN=CACNA1F /PROD=calcium channel, voltage-dependent, alpha 1Fsubunit /DB_XREF=gi:4885102 /UG=Hs.139263 calcium channel, voltage-dependent, alpha 1F subunit /FL=gb:AJ224874.1 gb:NM_005183.1 NM_005183 calcium channel, voltage-dependent, L type, alpha 1F subunit CACNA1F 778 NM_001256789 /// NM_001256790 /// NM_005183 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 208378_x_at NM_004464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004464.1 /DEF=Homo sapiens fibroblast growth factor 5 (FGF5), mRNA. /FEA=mRNA /GEN=FGF5 /PROD=fibroblast growth factor 5 /DB_XREF=gi:4758369 /UG=Hs.37055 fibroblast growth factor 5 /FL=gb:NM_004464.1 NM_004464 fibroblast growth factor 5 FGF5 2250 NM_001291812 /// NM_004464 /// NM_033143 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 208379_x_at NM_000910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000910.1 /DEF=Homo sapiens neuropeptide Y receptor Y2 (NPY2R), mRNA. /FEA=mRNA /GEN=NPY2R /PROD=neuropeptide Y receptor Y2 /DB_XREF=gi:4505446 /UG=Hs.37125 neuropeptide Y receptor Y2 /FL=gb:NM_000910.1 NM_000910 neuropeptide Y receptor Y2 NPY2R 4887 NM_000910 /// XM_005263033 /// XM_005263034 0001662 // behavioral fear response // inferred from electronic annotation /// 0002793 // positive regulation of peptide secretion // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007626 // locomotory behavior // traceable author statement /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046903 // secretion // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208380_at NM_006562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006562.3 /DEF=Homo sapiens transcription factor similar to D. melanogaster homeodomain protein lady bird late (LBX1), mRNA. /FEA=mRNA /GEN=LBX1 /PROD=transcription factor similar to D. melanogasterhomeodomain protein lady bird late /DB_XREF=gi:11184237 /UG=Hs.37128 transcription factor similar to D. melanogaster homeodomain protein lady bird late /FL=gb:NM_006562.3 NM_006562 ladybird homeobox 1 LBX1 10660 NM_006562 /// XM_005269443 0001947 // heart looping // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021920 // regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208381_s_at NM_003901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003901.1 /DEF=Homo sapiens sphingosine-1-phosphate lyase 1 (SGPL1), mRNA. /FEA=mRNA /GEN=SGPL1 /PROD=sphingosine-1-phosphate lyase 1 /DB_XREF=gi:10190652 /UG=Hs.186613 sphingosine-1-phosphate lyase 1 /FL=gb:NM_003901.1 NM_003901 sphingosine-1-phosphate lyase 1 SGPL1 8879 NM_003901 /// XM_005270263 /// XM_006718052 /// XM_006718053 0001553 // luteinization // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008117 // sphinganine-1-phosphate aldolase activity // inferred from direct assay /// 0008117 // sphinganine-1-phosphate aldolase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 208382_s_at D63882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63882.1 /DEF=Human HsLIM15 mRNA for HsLim15, complete cds. /FEA=mRNA /GEN=HsLIM15 /PROD=HsLim15 /DB_XREF=gi:1066000 /UG=Hs.37181 DMC1 (dosage suppressor of mck1, yeast homolog) meiosis-specific homologous recombination /FL=gb:D63882.1 gb:NM_007068.1 gb:D64108.1 D63882 DNA meiotic recombinase 1 DMC1 11144 NM_001278208 /// NM_007068 /// NR_103474 /// XM_006724110 /// XM_006724111 /// XM_006724112 /// XM_006724113 /// XR_430399 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009432 // SOS response // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 208383_s_at NM_002591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002591.1 /DEF=Homo sapiens phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1), mRNA. /FEA=mRNA /GEN=PCK1 /PROD=phosphoenolpyruvate carboxykinase 1 (soluble) /DB_XREF=gi:4505638 /UG=Hs.1872 phosphoenolpyruvate carboxykinase 1 (soluble) /FL=gb:L05144.1 gb:NM_002591.1 NM_002591 phosphoenolpyruvate carboxykinase 1 (soluble) PCK1 5105 NM_002591 /// XM_006723802 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017144 // drug metabolic process // traceable author statement /// 0032868 // response to insulin // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046327 // glycerol biosynthetic process from pyruvate // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004611 // phosphoenolpyruvate carboxykinase activity // inferred from electronic annotation /// 0004613 // phosphoenolpyruvate carboxykinase (GTP) activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208384_s_at NM_012216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012216.1 /DEF=Homo sapiens midline 2 (MID2), mRNA. /FEA=mRNA /GEN=MID2 /PROD=midline 2 /DB_XREF=gi:6912503 /UG=Hs.12256 midline 2 /FL=gb:NM_012216.1 NM_012216 midline 2 MID2 11043 NM_012216 /// NM_052817 /// XM_005262062 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 208385_at NM_016346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016346.1 /DEF=Homo sapiens nuclear receptor subfamily 2, group E, member 3 (NR2E3), mRNA. /FEA=mRNA /GEN=NR2E3 /PROD=nuclear receptor subfamily 2, group E, member 3 /DB_XREF=gi:7706514 /UG=Hs.187354 nuclear receptor subfamily 2, group E, member 3 /FL=gb:AF148128.1 gb:NM_016346.1 NM_016346 nuclear receptor subfamily 2, group E, member 3 NR2E3 10002 NM_001281446 /// NM_014249 /// NM_016346 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208386_x_at NM_007068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007068.1 /DEF=Homo sapiens DMC1 (dosage suppressor of mck1, yeast homolog) meiosis-specific homologous recombination (DMC1), mRNA. /FEA=mRNA /GEN=DMC1 /PROD=DMC1 (dosage suppressor of mck1, yeast homolog)meiosis-specific homologous recombination /DB_XREF=gi:5901995 /UG=Hs.37181 DMC1 (dosage suppressor of mck1, yeast homolog) meiosis-specific homologous recombination /FL=gb:D63882.1 gb:NM_007068.1 gb:D64108.1 NM_007068 DNA meiotic recombinase 1 DMC1 11144 NM_001278208 /// NM_007068 /// NR_103474 /// XM_006724110 /// XM_006724111 /// XM_006724112 /// XM_006724113 /// XR_430399 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009432 // SOS response // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 208387_s_at NM_006690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006690.2 /DEF=Homo sapiens matrix metalloproteinase 24 (membrane-inserted) (MMP24), mRNA. /FEA=mRNA /GEN=MMP24 /PROD=matrix metalloproteinase 24 (membrane-inserted) /DB_XREF=gi:13027806 /UG=Hs.3743 matrix metalloproteinase 24 (membrane-inserted) /FL=gb:NM_006690.2 gb:AF131284.1 gb:AB021227.1 NM_006690 matrix metallopeptidase 24 (membrane-inserted) MMP24 10893 NM_006690 0006508 // proteolysis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208388_at NM_014249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014249.1 /DEF=Homo sapiens nuclear receptor subfamily 2, group E, member 3 (NR2E3), mRNA. /FEA=mRNA /GEN=NR2E3 /PROD=nuclear receptor subfamily 2, group E, member 3 /DB_XREF=gi:7657394 /UG=Hs.187354 nuclear receptor subfamily 2, group E, member 3 /FL=gb:AF121129.1 gb:NM_014249.1 NM_014249 nuclear receptor subfamily 2, group E, member 3 NR2E3 10002 NM_001281446 /// NM_014249 /// NM_016346 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208389_s_at NM_004171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004171.1 /DEF=Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 2 (SLC1A2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC1A2 /PROD=solute carrier family 1 (glial high affinityglutamate transporter), member 2 /DB_XREF=gi:4759123 /UG=Hs.380 solute carrier family 1 (glial high affinity glutamate transporter), member 2 /FL=gb:NM_004171.1 gb:U03505.1 NM_004171 solute carrier family 1 (glial high affinity glutamate transporter), member 2 SLC1A2 6506 NM_001195728 /// NM_001252652 /// NM_004171 /// XM_005253066 /// XM_005253067 /// XM_006718277 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007632 // visual behavior // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation /// 0015501 // glutamate:sodium symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 208390_s_at U01104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01104.1 /DEF=Human glucagon-like peptide-1 receptor mRNA, complete cds. /FEA=mRNA /PROD=glucagon-like peptide-1 receptor /DB_XREF=gi:405081 /UG=Hs.165 glucagon-like peptide 1 receptor /FL=gb:U01104.1 gb:NM_002062.1 gb:U01157.1 gb:U10037.1 U01104 glucagon-like peptide 1 receptor GLP1R 2740 NM_002062 /// XM_006715065 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 208391_s_at NM_002062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002062.1 /DEF=Homo sapiens glucagon-like peptide 1 receptor (GLP1R), mRNA. /FEA=mRNA /GEN=GLP1R /PROD=glucagon-like peptide 1 receptor /DB_XREF=gi:4504016 /UG=Hs.165 glucagon-like peptide 1 receptor /FL=gb:U01104.1 gb:NM_002062.1 gb:U01157.1 gb:U10037.1 NM_002062 glucagon-like peptide 1 receptor GLP1R 2740 NM_002062 /// XM_006715065 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 208392_x_at NM_004510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004510.1 /DEF=Homo sapiens interferon-induced protein 75, 52kD (IFI75), mRNA. /FEA=mRNA /GEN=IFI75 /PROD=interferon-induced protein 75, 52kD /DB_XREF=gi:4758587 /UG=Hs.38125 interferon-induced protein 75, 52kD /FL=gb:L22343.1 gb:NM_004510.1 NM_004510 SP110 nuclear body protein SP110 3431 NM_001185015 /// NM_004509 /// NM_004510 /// NM_080424 /// XM_005246525 /// XM_005246527 /// XM_006712486 /// XM_006712487 /// XM_006712488 /// XM_006712489 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208393_s_at NM_005732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005732.1 /DEF=Homo sapiens RAD50 (S. cerevisiae) homolog (RAD50), mRNA. /FEA=mRNA /GEN=RAD50 /PROD=RAD50 (S. cerevisiae) homolog /DB_XREF=gi:5032016 /UG=Hs.41587 RAD50 (S. cerevisiae) homolog /FL=gb:NM_005732.1 NM_005732 RAD50 homolog (S. cerevisiae) RAD50 10111 NM_005732 /// NM_133482 0000019 // regulation of mitotic recombination // inferred from direct assay /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208394_x_at NM_007036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007036.2 /DEF=Homo sapiens endothelial cell-specific molecule 1 (ESM1), mRNA. /FEA=mRNA /GEN=ESM1 /PROD=endothelial cell-specific molecule 1 precursor /DB_XREF=gi:13259505 /UG=Hs.41716 endothelial cell-specific molecule 1 /FL=gb:NM_007036.2 NM_007036 endothelial cell-specific molecule 1 ESM1 11082 NM_001135604 /// NM_007036 0001525 // angiogenesis // inferred from expression pattern /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 1902204 // positive regulation of hepatocyte growth factor receptor signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation 0005171 // hepatocyte growth factor receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008083 // growth factor activity // non-traceable author statement 208395_s_at NM_014825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014825.1 /DEF=Homo sapiens KIAA0539 gene product (KIAA0539), mRNA. /FEA=mRNA /GEN=KIAA0539 /PROD=KIAA0539 gene product /DB_XREF=gi:7662171 /UG=Hs.18759 KIAA0539 gene product /FL=gb:AB011111.1 gb:NM_014825.1 NM_014825 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) URB1 9875 NM_014825 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208396_s_at NM_005019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005019.1 /DEF=Homo sapiens phosphodiesterase 1A, calmodulin-dependent (PDE1A), mRNA. /FEA=mRNA /GEN=PDE1A /PROD=phosphodiesterase 1A, calmodulin-dependent /DB_XREF=gi:4826891 /UG=Hs.41717 phosphodiesterase 1A, calmodulin-dependent /FL=gb:U40370.1 gb:NM_005019.1 NM_005019 phosphodiesterase 1A, calmodulin-dependent PDE1A 5136 NM_001003683 /// NM_001258312 /// NM_001258313 /// NM_001258314 /// NM_005019 /// XM_005246635 /// XM_005246636 /// XM_005246637 /// XM_006712574 /// XM_006712575 /// XM_006712576 /// XM_006712577 /// XM_006712578 /// XM_006712579 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0034391 // regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046069 // cGMP catabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004117 // calmodulin-dependent cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048101 // calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 208397_x_at U39195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39195.1 /DEF=Human clone KGP G-protein coupled inwardly rectifying potassium channel mRNA, complete cds. /FEA=mRNA /PROD=G-protein coupled inwardly rectifying potassiumchannel /DB_XREF=gi:1055025 /UG=Hs.193044 potassium inwardly-rectifying channel, subfamily J, member 5 /FL=gb:U39195.1 gb:U52154.1 gb:NM_000890.2 U39195 potassium inwardly-rectifying channel, subfamily J, member 5 KCNJ5 3762 NM_000890 /// XM_005271543 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // traceable author statement 208398_s_at NM_004865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004865.1 /DEF=Homo sapiens TBP-like 1 (TBPL1), mRNA. /FEA=mRNA /GEN=TBPL1 /PROD=TBP-like 1 /DB_XREF=gi:4759233 /UG=Hs.13993 TBP-like 1 /FL=gb:AF130312.1 gb:NM_004865.1 NM_004865 TBP-like 1 TBPL1 9519 NM_001253676 /// NM_004865 0001675 // acrosome assembly // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005672 // transcription factor TFIIA complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 208399_s_at NM_000114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000114.1 /DEF=Homo sapiens endothelin 3 (EDN3), mRNA. /FEA=mRNA /GEN=EDN3 /PROD=endothelin 3 precursor /DB_XREF=gi:4557544 /UG=Hs.1408 endothelin 3 /FL=gb:J05081.1 gb:NM_000114.1 NM_000114 endothelin 3 EDN3 1908 NM_000114 /// NM_207032 /// NM_207033 /// NM_207034 /// XM_005260312 /// XM_005260313 /// XM_005260314 /// XM_006723734 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from direct assay /// 0014826 // vein smooth muscle contraction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0042310 // vasoconstriction // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from direct assay 208400_at U01157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01157.1 /DEF=Human glucagon-like peptide-1 receptor mRNA with CA dinucleotide repeat, complete cds. /FEA=mRNA /PROD=glucagon-like peptide-1 receptor /DB_XREF=gi:684918 /UG=Hs.165 glucagon-like peptide 1 receptor /FL=gb:U01104.1 gb:NM_002062.1 gb:U01157.1 gb:U10037.1 U01157 glucagon-like peptide 1 receptor GLP1R 2740 NM_002062 /// XM_006715065 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 208401_s_at U01157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01157.1 /DEF=Human glucagon-like peptide-1 receptor mRNA with CA dinucleotide repeat, complete cds. /FEA=mRNA /PROD=glucagon-like peptide-1 receptor /DB_XREF=gi:684918 /UG=Hs.165 glucagon-like peptide 1 receptor /FL=gb:U01104.1 gb:NM_002062.1 gb:U01157.1 gb:U10037.1 U01157 glucagon-like peptide 1 receptor GLP1R 2740 NM_002062 /// XM_006715065 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 208402_at NM_002190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002190.1 /DEF=Homo sapiens interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) (IL17), mRNA. /FEA=mRNA /GEN=IL17 /PROD=interleukin 17 /DB_XREF=gi:4504650 /UG=Hs.41724 interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) /FL=gb:U32659.1 gb:NM_002190.1 NM_002190 interleukin 17A IL17A 3605 NM_002190 0006486 // protein glycosylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008219 // cell death // traceable author statement /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0072537 // fibroblast activation // inferred from direct assay /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation 208403_x_at NM_002382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002382.1 /DEF=Homo sapiens MAX protein (MAX), mRNA. /FEA=mRNA /GEN=MAX /PROD=MAX protein /DB_XREF=gi:4505114 /UG=Hs.42712 MAX protein /FL=gb:NM_002382.1 NM_002382 MYC associated factor X MAX 4149 NM_001271068 /// NM_001271069 /// NM_002382 /// NM_145112 /// NM_145113 /// NM_145114 /// NM_145116 /// NM_197957 /// NR_073137 /// NR_073138 /// XR_429315 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 208404_x_at NM_000890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000890.2 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5), mRNA. /FEA=mRNA /GEN=KCNJ5 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 5 /DB_XREF=gi:4826799 /UG=Hs.193044 potassium inwardly-rectifying channel, subfamily J, member 5 /FL=gb:U39195.1 gb:U52154.1 gb:NM_000890.2 NM_000890 potassium inwardly-rectifying channel, subfamily J, member 5 KCNJ5 3762 NM_000890 /// XM_005271543 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // traceable author statement 208405_s_at NM_006016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006016.1 /DEF=Homo sapiens CD164 antigen, sialomucin (CD164), mRNA. /FEA=mRNA /GEN=CD164 /PROD=CD164 antigen, sialomucin /DB_XREF=gi:5174406 /UG=Hs.43910 CD164 antigen, sialomucin /FL=gb:D14043.1 gb:NM_006016.1 NM_006016 CD164 molecule, sialomucin CD164 8763 NM_001142401 /// NM_001142402 /// NM_001142403 /// NM_001142404 /// NM_006016 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0030097 // hemopoiesis // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208406_s_at NM_004810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004810.1 /DEF=Homo sapiens GRB2-related adaptor protein 2 (GRAP2), mRNA. /FEA=mRNA /GEN=GRAP2 /PROD=GRB2-related adaptor protein 2 /DB_XREF=gi:4758475 /UG=Hs.193076 GRB2-related adaptor protein 2 /FL=gb:AF102694.1 gb:NM_004810.1 NM_004810 GRB2-related adaptor protein 2 GRAP2 9402 NM_001291824 /// NM_001291825 /// NM_001291826 /// NM_001291828 /// NM_004810 /// XM_005261836 /// XM_005261841 /// XM_006724376 0007265 // Ras protein signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208407_s_at NM_001331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001331.1 /DEF=Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), mRNA. /FEA=mRNA /GEN=CTNND1 /PROD=catenin (cadherin-associated protein), delta 1 /DB_XREF=gi:10835009 /UG=Hs.166011 catenin (cadherin-associated protein), delta 1 /FL=gb:NM_001331.1 gb:AF062317.1 NM_001331 catenin (cadherin-associated protein), delta 1 /// TMX2-CTNND1 readthrough (NMD candidate) CTNND1 /// TMX2-CTNND1 1500 /// 100528016 NM_001085458 /// NM_001085459 /// NM_001085460 /// NM_001085461 /// NM_001085462 /// NM_001085463 /// NM_001085464 /// NM_001085465 /// NM_001085466 /// NM_001085467 /// NM_001085468 /// NM_001085469 /// NM_001206883 /// NM_001206884 /// NM_001206885 /// NM_001206886 /// NM_001206887 /// NM_001206888 /// NM_001206889 /// NM_001206890 /// NM_001206891 /// NM_001331 /// NR_037646 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0060690 // epithelial cell differentiation involved in salivary gland development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 208408_at NM_002825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002825.1 /DEF=Homo sapiens pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) (PTN), mRNA. /FEA=mRNA /GEN=PTN /PROD=pleiotrophin (heparin binding growth factor 8,neurite growth-promoting factor 1) /DB_XREF=gi:4506280 /UG=Hs.44 pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) /FL=gb:AB004306.1 gb:NM_002825.1 NM_002825 pleiotrophin PTN 5764 NM_002825 /// XM_005250515 /// XM_005250516 0001503 // ossification // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 208409_at NM_007163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007163.1 /DEF=Homo sapiens solute carrier family 14 (urea transporter), member 2 (SLC14A2), mRNA. /FEA=mRNA /GEN=SLC14A2 /PROD=solute carrier family 14 (urea transporter),member 2 /DB_XREF=gi:6005875 /UG=Hs.193377 solute carrier family 14 (urea transporter), member 2 /FL=gb:NM_007163.1 NM_007163 putative uncharacterized protein encoded by LINC00596-like /// solute carrier family 14 (urea transporter), member 2 LOC101930602 /// SLC14A2 8170 /// 101930602 NM_001242692 /// NM_007163 /// XM_005276012 0006810 // transport // inferred from electronic annotation /// 0015840 // urea transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071918 // urea transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015204 // urea transmembrane transporter activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from direct assay 208410_x_at NM_001142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001142.2 /DEF=Homo sapiens amelogenin (X chromosome, amelogenesis imperfecta 1) (AMELX), mRNA. /FEA=mRNA /GEN=AMELX /PROD=amelogenin (X chromosome, amelogenesisimperfecta 1) /DB_XREF=gi:6715562 /UG=Hs.46329 amelogenin (X chromosome, amelogenesis imperfecta 1) /FL=gb:M86932.1 gb:NM_001142.2 NM_001142 amelogenin, X-linked AMELX 265 NM_001142 /// NM_182680 /// NM_182681 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031214 // biomineral tissue development // traceable author statement /// 0032967 // positive regulation of collagen biosynthetic process // inferred from sequence or structural similarity /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0034505 // tooth mineralization // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0050801 // ion homeostasis // traceable author statement /// 0070166 // enamel mineralization // inferred from mutant phenotype /// 0070172 // positive regulation of tooth mineralization // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0030345 // structural constituent of tooth enamel // inferred from direct assay /// 0030345 // structural constituent of tooth enamel // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0046848 // hydroxyapatite binding // inferred from sequence or structural similarity 208411_x_at NM_006239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006239.1 /DEF=Homo sapiens protein phosphatase, EF hand calcium-binding domain 2 (PPEF2), mRNA. /FEA=mRNA /GEN=PPEF2 /PROD=protein phosphatase, EF hand calcium-bindingdomain 2 /DB_XREF=gi:5453943 /UG=Hs.193558 protein phosphatase, EF hand calcium-binding domain 2 /FL=gb:AF023456.1 gb:AF023457.1 gb:NM_006239.1 NM_006239 protein phosphatase, EF-hand calcium binding domain 2 PPEF2 5470 NM_006239 /// NM_152933 /// NM_152934 /// XM_006714241 0006470 // protein dephosphorylation // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0043405 // regulation of MAP kinase activity // inferred by curator /// 0043409 // negative regulation of MAPK cascade // inferred from direct assay /// 0043506 // regulation of JUN kinase activity // inferred by curator /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050906 // detection of stimulus involved in sensory perception // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 208412_s_at NM_015854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015854.1 /DEF=Homo sapiens retinoic acid receptor-beta associated open reading frame (LOC51036), mRNA. /FEA=mRNA /GEN=LOC51036 /PROD=retinoic acid receptor-beta associated openreading frame /DB_XREF=gi:7705655 /UG=Hs.1938 retinoic acid receptor-beta associated open reading frame /FL=gb:NM_015854.1 NM_015854 retinoic acid receptor, beta RARB 5915 NM_000965 /// NM_001290216 /// NM_001290217 /// NM_001290266 /// NM_001290276 /// NM_001290277 /// NM_001290300 /// NM_016152 /// NR_110892 /// NR_110893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021756 // striatum development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation 208413_at NM_015854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015854.1 /DEF=Homo sapiens retinoic acid receptor-beta associated open reading frame (LOC51036), mRNA. /FEA=mRNA /GEN=LOC51036 /PROD=retinoic acid receptor-beta associated openreading frame /DB_XREF=gi:7705655 /UG=Hs.1938 retinoic acid receptor-beta associated open reading frame /FL=gb:NM_015854.1 NM_015854 retinoic acid receptor, beta RARB 5915 NM_000965 /// NM_001290216 /// NM_001290217 /// NM_001290266 /// NM_001290276 /// NM_001290277 /// NM_001290300 /// NM_016152 /// NR_110892 /// NR_110893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021756 // striatum development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation 208414_s_at NM_002146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002146.1 /DEF=Homo sapiens homeo box B3 (HOXB3), mRNA. /FEA=mRNA /GEN=HOXB3 /PROD=homeo box B3 /DB_XREF=gi:4504466 /UG=Hs.166014 homeo box B3 /FL=gb:NM_002146.1 NM_002146 homeobox B3 HOXB3 3213 NM_002146 /// XM_005257277 /// XM_005257280 /// XM_005257282 /// XM_006721854 /// XM_006721855 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021546 // rhombomere development // inferred from electronic annotation /// 0021615 // glossopharyngeal nerve morphogenesis // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208415_x_at NM_005537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005537.1 /DEF=Homo sapiens inhibitor of growth 1 family, member 1 (ING1), mRNA. /FEA=mRNA /GEN=ING1 /PROD=inhibitor of growth 1 family, member 1 /DB_XREF=gi:5031792 /UG=Hs.46700 inhibitor of growth 1 family, member 1 /FL=gb:AF001954.1 gb:NM_005537.1 NM_005537 inhibitor of growth family, member 1 ING1 3621 NM_001267728 /// NM_005537 /// NM_198217 /// NM_198218 /// NM_198219 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208416_s_at NM_000347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000347.2 /DEF=Homo sapiens spectrin, beta, erythrocytic (includes spherocytosis, clinical type I) (SPTB), mRNA. /FEA=mRNA /GEN=SPTB /PROD=spectrin, beta, erythrocytic (includesspherocytosis, clinical type I) /DB_XREF=gi:10334855 /UG=Hs.47431 spectrin, beta, erythrocytic (includes spherocytosis, clinical type I) /FL=gb:NM_000347.2 NM_000347 spectrin, beta, erythrocytic SPTB 6710 NM_000347 /// NM_001024858 /// XM_005268023 /// XM_006720241 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 208417_at NM_020996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020996.1 /DEF=Homo sapiens fibroblast growth factor 6 (FGF6), mRNA. /FEA=mRNA /GEN=FGF6 /PROD=fibroblast growth factor 6 /DB_XREF=gi:10337586 /UG=Hs.166015 fibroblast growth factor 6 /FL=gb:NM_020996.1 NM_020996 fibroblast growth factor 6 FGF6 2251 NM_020996 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 208420_x_at NM_003170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003170.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 6 homolog (SUPT6H), mRNA. /FEA=mRNA /GEN=SUPT6H /PROD=suppressor of Ty (S.cerevisiae) 6 homolog /DB_XREF=gi:11321572 /UG=Hs.12303 suppressor of Ty (S.cerevisiae) 6 homolog /FL=gb:NM_003170.1 gb:U46691.1 NM_003170 suppressor of Ty 6 homolog (S. cerevisiae) SUPT6H 6830 NM_003170 /// XM_005258026 /// XM_005258027 /// XM_006722042 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0045191 // regulation of isotype switching // inferred from sequence or structural similarity /// 0050684 // regulation of mRNA processing // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208421_at NM_015880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015880.1 /DEF=Homo sapiens RIG-like 14-1 (LOC51047), mRNA. /FEA=mRNA /GEN=LOC51047 /PROD=RIG-like 14-1 /DB_XREF=gi:7705669 /UG=Hs.129699 RIG-like 14-1 /FL=gb:AF034207.1 gb:NM_015880.1 NM_015880 208422_at NM_002445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002445.1 /DEF=Homo sapiens macrophage scavenger receptor 1 (MSR1), mRNA. /FEA=mRNA /GEN=MSR1 /PROD=macrophage scavenger receptor 1 /DB_XREF=gi:4505258 /UG=Hs.49 macrophage scavenger receptor 1 /FL=gb:NM_002445.1 NM_002445 macrophage scavenger receptor 1 MSR1 4481 NM_002445 /// NM_138715 /// NM_138716 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042221 // response to chemical // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from sequence or structural similarity 208423_s_at NM_002445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002445.1 /DEF=Homo sapiens macrophage scavenger receptor 1 (MSR1), mRNA. /FEA=mRNA /GEN=MSR1 /PROD=macrophage scavenger receptor 1 /DB_XREF=gi:4505258 /UG=Hs.49 macrophage scavenger receptor 1 /FL=gb:NM_002445.1 NM_002445 macrophage scavenger receptor 1 MSR1 4481 NM_002445 /// NM_138715 /// NM_138716 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042221 // response to chemical // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from sequence or structural similarity 208424_s_at NM_020313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020313.1 /DEF=Homo sapiens hypothetical protein (LOC57019), mRNA. /FEA=mRNA /GEN=LOC57019 /PROD=hypothetical protein /DB_XREF=gi:10092672 /UG=Hs.4900 hypothetical protein /FL=gb:NM_020313.1 NM_020313 cytokine induced apoptosis inhibitor 1 CIAPIN1 57019 NM_020313 /// XM_005256061 /// XM_005256062 /// XM_005256063 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 208425_s_at NM_015623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015623.1 /DEF=Homo sapiens DKFZP564D166 protein (DKFZP564D166), mRNA. /FEA=mRNA /GEN=DKFZP564D166 /PROD=DKFZP564D166 protein /DB_XREF=gi:7661607 /UG=Hs.4996 putative ankyrin-repeat containing protein /FL=gb:NM_015623.1 NM_015623 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 TANC2 26115 NM_015623 /// NM_025185 /// NM_030658 /// XM_005257201 /// XM_005257203 /// XM_006721806 /// XM_006721807 /// XM_006721808 /// XM_006721809 /// XM_006721810 /// XM_006721811 0001701 // in utero embryonic development // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 208426_x_at NM_002255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002255.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), mRNA. /FEA=mRNA /GEN=KIR2DL4 /PROD=killer cell immunoglobulin-like receptor, twodomains, long cytoplasmic tail, 4 /DB_XREF=gi:4504870 /UG=Hs.166085 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 /FL=gb:AF002981.1 gb:NM_002255.1 NM_002255 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 KIR2DL4 3805 NM_001080770 /// NM_001080772 /// NM_001258383 /// NM_002255 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208427_s_at NM_004432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004432.1 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (ELAVL2), mRNA. /FEA=mRNA /GEN=ELAVL2 /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 2 /DB_XREF=gi:4758261 /UG=Hs.166109 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 /FL=gb:NM_004432.1 gb:U12431.1 NM_004432 ELAV like neuron-specific RNA binding protein 2 ELAVL2 1993 NM_001171195 /// NM_001171197 /// NM_004432 /// XM_005251390 /// XM_005251391 /// XM_005251392 /// XM_005251393 /// XM_005251394 /// XM_005251395 /// XM_006716733 /// XM_006716734 /// XM_006716735 /// XM_006716736 /// XM_006716737 /// XM_006716738 0006355 // regulation of transcription, DNA-templated // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208428_at NM_018833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018833.1 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 3 (ABCB3), transcript variant 2, mRNA. /FEA=mRNA /GEN=ABCB3 /PROD=ATP-binding cassette, sub-family B, member 3,isoform 2 /DB_XREF=gi:9961247 /UG=Hs.502 ATP-binding cassette, sub-family B (MDRTAP), member 3 /FL=gb:AF105151.1 gb:AF078671.1 gb:NM_018833.1 NM_018833 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) TAP2 6891 NM_000544 /// NM_001290043 /// NM_018833 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // not recorded /// 0002485 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent // not recorded /// 0002489 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent // inferred from mutant phenotype /// 0002591 // positive regulation of antigen processing and presentation of peptide antigen via MHC class I // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015833 // peptide transport // traceable author statement /// 0015833 // peptide transport // /// 0016032 // viral process // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from direct assay /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0046967 // cytosol to ER transport // inferred from mutant phenotype /// 0046968 // peptide antigen transport // inferred from direct assay /// 0046968 // peptide antigen transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015197 // peptide transporter activity // inferred from genetic interaction /// 0015421 // oligopeptide-transporting ATPase activity // /// 0015433 // peptide antigen-transporting ATPase activity // inferred from mutant phenotype /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // /// 0042605 // peptide antigen binding // /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // /// 0046980 // tapasin binding // inferred from sequence or structural similarity 208429_x_at NM_000457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000457.1 /DEF=Homo sapiens hepatocyte nuclear factor 4, alpha (HNF4A), mRNA. /FEA=mRNA /GEN=HNF4A /PROD=hepatocyte nuclear factor 4, alpha /DB_XREF=gi:4504442 /UG=Hs.54424 hepatocyte nuclear factor 4, alpha /FL=gb:NM_000457.1 NM_000457 hepatocyte nuclear factor 4, alpha HNF4A 3172 NM_000457 /// NM_001030003 /// NM_001030004 /// NM_001258355 /// NM_001287182 /// NM_001287183 /// NM_001287184 /// NM_175914 /// NM_178849 /// NM_178850 /// XM_005260407 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006591 // ornithine metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from mutant phenotype /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0060398 // regulation of growth hormone receptor signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208430_s_at NM_001390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001390.1 /DEF=Homo sapiens dystrobrevin, alpha (DTNA), mRNA. /FEA=mRNA /GEN=DTNA /PROD=dystrobrevin, alpha /DB_XREF=gi:4503406 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:NM_001390.1 NM_001390 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208431_s_at NM_003320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003320.1 /DEF=Homo sapiens tubby (mouse) homolog (TUB), mRNA. /FEA=mRNA /GEN=TUB /PROD=tubby (mouse) homolog /DB_XREF=gi:4507726 /UG=Hs.54468 tubby (mouse) homolog /FL=gb:U54644.1 gb:NM_003320.1 NM_003320 tubby bipartite transcription factor TUB 7275 NM_003320 /// NM_177972 /// XM_005253109 /// XM_006718303 0006909 // phagocytosis // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009584 // detection of visible light // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0044259 // multicellular organismal macromolecule metabolic process // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008020 // G-protein coupled photoreceptor activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 208432_s_at NM_000721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000721.1 /DEF=Homo sapiens calcium channel, voltage-dependent, alpha 1E subunit (CACNA1E), mRNA. /FEA=mRNA /GEN=CACNA1E /PROD=calcium channel, voltage-dependent, alpha 1Esubunit /DB_XREF=gi:4502528 /UG=Hs.166110 calcium channel, voltage-dependent, alpha 1E subunit /FL=gb:NM_000721.1 gb:L29384.1 NM_000721 calcium channel, voltage-dependent, R type, alpha 1E subunit CACNA1E 777 NM_000721 /// NM_001205293 /// NM_001205294 0001662 // behavioral fear response // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded /// 0090273 // regulation of somatostatin secretion // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 208433_s_at NM_017522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017522.1 /DEF=Homo sapiens apolipoprotein E receptor 2 (HSZ75190), mRNA. /FEA=mRNA /GEN=HSZ75190 /PROD=apolipoprotein E receptor 2 /DB_XREF=gi:8923799 /UG=Hs.54481 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor /FL=gb:NM_017522.1 NM_017522 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor LRP8 7804 NM_001018054 /// NM_004631 /// NM_017522 /// NM_033300 /// XM_005271173 /// XM_005271174 /// XM_005271175 /// XM_005271176 /// XM_006710881 /// XM_006710882 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001523 // retinoid metabolic process // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006897 // endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0021541 // ammon gyrus development // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0038026 // reelin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred by curator /// 0038025 // reelin receptor activity // inferred from sequence or structural similarity 208434_at NM_004991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004991.1 /DEF=Homo sapiens myelodysplasia syndrome 1 (MDS1), mRNA. /FEA=mRNA /GEN=MDS1 /PROD=myelodysplasia syndrome protein 1 /DB_XREF=gi:4826827 /UG=Hs.54504 myelodysplasia syndrome 1 /FL=gb:U43292.1 gb:NM_004991.1 NM_004991 MDS1 and EVI1 complex locus MECOM 2122 NM_001105077 /// NM_001105078 /// NM_001163999 /// NM_001164000 /// NM_001205194 /// NM_004991 /// NM_005241 /// XM_005247213 /// XM_005247214 /// XM_005247215 /// XM_005247216 /// XM_005247219 /// XM_005247220 /// XM_005247221 /// XM_005247223 /// XM_005247224 /// XM_005247225 /// XM_005247226 /// XM_006713536 /// XM_006713537 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060039 // pericardium development // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208435_s_at NM_001652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001652.1 /DEF=Homo sapiens aquaporin 6, kidney specific (AQP6), mRNA. /FEA=mRNA /GEN=AQP6 /PROD=aquaporin 6 /DB_XREF=gi:4502184 /UG=Hs.54505 aquaporin 6, kidney specific /FL=gb:U48408.1 gb:NM_001652.1 NM_001652 aquaporin 6, kidney specific AQP6 363 NM_001652 /// NM_053286 /// XM_006719375 /// XR_245925 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015706 // nitrate transport // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from expression pattern /// 0055085 // transmembrane transport // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005253 // anion channel activity // not recorded /// 0015112 // nitrate transmembrane transporter activity // inferred from electronic annotation /// 0015250 // water channel activity // traceable author statement 208436_s_at NM_004030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004030.1 /DEF=Homo sapiens interferon regulatory factor 7 (IRF7), transcript variant c, mRNA. /FEA=mRNA /GEN=IRF7 /PROD=interferon regulatory factor 7, transcriptvariant c /DB_XREF=gi:4809285 /UG=Hs.166120 interferon regulatory factor 7 /FL=gb:NM_004030.1 NM_004030 interferon regulatory factor 7 IRF7 3665 NM_001572 /// NM_004029 /// NM_004030 /// NM_004031 /// XM_005252906 /// XM_005252907 /// XM_005252908 /// XM_005252909 /// XM_006725137 /// XM_006725138 /// XM_006725139 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002819 // regulation of adaptive immune response // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0019043 // establishment of viral latency // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032607 // interferon-alpha production // inferred from sequence or structural similarity /// 0032608 // interferon-beta production // inferred from sequence or structural similarity /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034124 // regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0034127 // regulation of MyD88-independent toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0039530 // MDA-5 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0045655 // regulation of monocyte differentiation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046730 // induction of host immune response by virus // traceable author statement /// 0046731 // passive induction of host immune response by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation /// 2000110 // negative regulation of macrophage apoptotic process // traceable author statement 0005581 // collagen trimer // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208437_at NM_000083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000083.1 /DEF=Homo sapiens chloride channel 1 , skeletal muscle (Thomsen disease, autosomal dominant) (CLCN1), mRNA. /FEA=mRNA /GEN=CLCN1 /PROD=chloride channel 1 /DB_XREF=gi:4502866 /UG=Hs.121483 chloride channel 1 , skeletal muscle (Thomsen disease, autosomal dominant) /FL=gb:NM_000083.1 NM_000083 chloride channel, voltage-sensitive 1 CLCN1 1180 NM_000083 /// NR_046453 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 208438_s_at NM_005248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005248.1 /DEF=Homo sapiens Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR), mRNA. /FEA=mRNA /GEN=FGR /PROD=Gardner-Rasheed feline sarcoma viral (v-fgr)oncogene homolog /DB_XREF=gi:4885234 /UG=Hs.1422 Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog /FL=gb:M19722.1 gb:NM_005248.1 NM_005248 FGR proto-oncogene, Src family tyrosine kinase FGR 2268 NM_001042729 /// NM_001042747 /// NM_005248 /// XM_006710452 0002376 // immune system process // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009615 // response to virus // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045088 // regulation of innate immune response // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050764 // regulation of phagocytosis // inferred from sequence or structural similarity /// 0050830 // defense response to Gram-positive bacterium // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0034987 // immunoglobulin receptor binding // inferred from sequence or structural similarity /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay 208439_s_at NM_015839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015839.1 /DEF=Homo sapiens ficolin (collagenfibrinogen domain-containing lectin) 2 (hucolin) (FCN2), transcript variant SV3, mRNA. /FEA=mRNA /GEN=FCN2 /PROD=ficolin 2 isoform d precursor /DB_XREF=gi:8051589 /UG=Hs.54517 ficolin (collagenfibrinogen domain-containing lectin) 2 (hucolin) /FL=gb:NM_015839.1 NM_015839 ficolin (collagen/fibrinogen domain containing lectin) 2 FCN2 2220 NM_004108 /// NM_015837 /// NM_015838 /// NM_015839 /// XM_006717015 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0008228 // opsonization // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 208440_at NM_007354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007354.1 /DEF=Homo sapiens putative GR6 protein (GR6), mRNA. /FEA=mRNA /GEN=GR6 /PROD=putative GR6 protein /DB_XREF=gi:6680080 /UG=Hs.194283 putative GR6 protein /FL=gb:AF008192.1 gb:NM_007354.1 NM_007354 chromosome 3 open reading frame 27 C3orf27 23434 NM_007354 208441_at NM_015883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015883.1 /DEF=Homo sapiens clone 1900 unknown protein (LOC51049), mRNA. /FEA=mRNA /GEN=LOC51049 /PROD=clone 1900 unknown protein /DB_XREF=gi:7705673 /UG=Hs.129705 clone 1900 unknown protein /FL=gb:AF020763.1 gb:NM_015883.1 NM_015883 insulin-like growth factor 1 receptor IGF1R 3480 NM_000875 /// NM_001291858 /// NM_152452 /// XM_005254896 /// XM_005254897 /// XM_006720486 /// XM_006720487 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051389 // inactivation of MAPKK activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction 208442_s_at NM_000051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000051.1 /DEF=Homo sapiens ataxia telangiectasia mutated (includes complementation groups A, C and D) (ATM), mRNA. /FEA=mRNA /GEN=ATM /PROD=ataxia telangiectasia mutated (includescomplementation groups A, C and D) /DB_XREF=gi:4502266 /UG=Hs.194382 ataxia telangiectasia mutated (includes complementation groups A, C and D) /FL=gb:U33841.1 gb:NM_000051.1 NM_000051 ATM serine/threonine kinase ATM 472 NM_000051 /// NM_138292 /// NM_138293 /// XM_005271561 /// XM_005271562 /// XM_005271564 /// XM_006718843 /// XM_006718844 /// XM_006718845 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0002331 // pre-B cell allelic exclusion // inferred from sequence or structural similarity /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007292 // female gamete generation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048599 // oocyte development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0072434 // signal transduction involved in mitotic G2 DNA damage checkpoint // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0035174 // histone serine kinase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 208443_x_at NM_006884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006884.1 /DEF=Homo sapiens short stature homeobox 2 (SHOX2), transcript variant SHOX2a, mRNA. /FEA=mRNA /GEN=SHOX2 /PROD=short stature homeobox 2, isoform a /DB_XREF=gi:6031199 /UG=Hs.55967 short stature homeobox 2 /FL=gb:NM_006884.1 NM_006884 short stature homeobox 2 SHOX2 6474 NM_001163678 /// NM_003030 /// NM_006884 /// XM_006713727 /// XM_006713728 /// XM_006713729 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003170 // heart valve development // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208445_s_at NM_023005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023005.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 1B (BAZ1B), mRNA. /FEA=mRNA /GEN=BAZ1B /PROD=bromodomain adjacent to zinc finger domain, 1B /DB_XREF=gi:12711667 /UG=Hs.194688 bromodomain adjacent to zinc finger domain, 1B /FL=gb:NM_023005.1 gb:AF072810.1 NM_023005 bromodomain adjacent to zinc finger domain, 1B BAZ1B 9031 NM_023005 /// NM_032408 /// XM_005250683 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034725 // DNA replication-dependent nucleosome disassembly // inferred from mutant phenotype /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay /// 0071884 // vitamin D receptor activator activity // inferred from electronic annotation 208446_s_at NM_007323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007323.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog interacting protein, receptor activation anchor (MADHIP), transcript variant 2, mRNA. /FEA=mRNA /GEN=MADHIP /PROD=Smad anchor for receptor activation, isoform 2 /DB_XREF=gi:6552336 /UG=Hs.194716 MAD (mothers against decapentaplegic, Drosophila) homolog interacting protein, receptor activation anchor /FL=gb:AF130420.1 gb:NM_007323.1 NM_007323 zinc finger, FYVE domain containing 9 ZFYVE9 9372 NM_004799 /// NM_007323 /// NM_007324 0006508 // proteolysis // non-traceable author statement /// 0006897 // endocytosis // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008236 // serine-type peptidase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208447_s_at NM_002764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002764.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase 1 (PRPS1), mRNA. /FEA=mRNA /GEN=PRPS1 /PROD=phosphoribosyl pyrophosphate synthetase 1 /DB_XREF=gi:4506126 /UG=Hs.56 phosphoribosyl pyrophosphate synthetase 1 /FL=gb:NM_002764.1 NM_002764 phosphoribosyl pyrophosphate synthetase 1 PRPS1 5631 NM_001204402 /// NM_002764 0005975 // carbohydrate metabolic process // traceable author statement /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // traceable author statement /// 0006144 // purine nucleobase metabolic process // inferred from mutant phenotype /// 0006164 // purine nucleotide biosynthetic process // inferred from mutant phenotype /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // non-traceable author statement /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034418 // urate biosynthetic process // inferred from mutant phenotype /// 0044249 // cellular biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046101 // hypoxanthine biosynthetic process // inferred from mutant phenotype 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // not recorded /// 0004749 // ribose phosphate diphosphokinase activity // inferred from direct assay /// 0004749 // ribose phosphate diphosphokinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208448_x_at NM_002173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002173.1 /DEF=Homo sapiens interferon, alpha 16 (IFNA16), mRNA. /FEA=mRNA /GEN=IFNA16 /PROD=interferon, alpha 16 /DB_XREF=gi:4504592 /UG=Hs.56303 interferon, alpha 16 /FL=gb:M28585.1 gb:NM_002173.1 NM_002173 interferon, alpha 16 IFNA16 3449 NM_002173 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 208449_s_at NM_006119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006119.1 /DEF=Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), mRNA. /FEA=mRNA /GEN=FGF8 /PROD=fibroblast growth factor 8 (androgen-induced) /DB_XREF=gi:5174438 /UG=Hs.57710 fibroblast growth factor 8 (androgen-induced) /FL=gb:U36223.1 gb:U46212.1 gb:NM_006119.1 NM_006119 fibroblast growth factor 8 (androgen-induced) FGF8 2253 NM_001206389 /// NM_006119 /// NM_033163 /// NM_033164 /// NM_033165 0000165 // MAPK cascade // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001656 // metanephros development // inferred from expression pattern /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from expression pattern /// 0001839 // neural plate morphogenesis // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007369 // gastrulation // non-traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008078 // mesodermal cell migration // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008406 // gonad development // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021543 // pallium development // inferred from electronic annotation /// 0021544 // subpallium development // inferred from electronic annotation /// 0021798 // forebrain dorsal/ventral pattern formation // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from electronic annotation /// 0030917 // midbrain-hindbrain boundary development // inferred from electronic annotation /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from expression pattern /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055026 // negative regulation of cardiac muscle tissue development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from electronic annotation /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from electronic annotation /// 0060348 // bone development // inferred from mutant phenotype /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060563 // neuroepithelial cell differentiation // inferred from direct assay /// 0071542 // dopaminergic neuron differentiation // inferred from direct assay /// 0090134 // cell migration involved in mesendoderm migration // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from electronic annotation 208450_at NM_006498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006498.1 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 2 (galectin 2) (LGALS2), mRNA. /FEA=CDS /GEN=LGALS2 /PROD=lectin, galactoside-binding, soluble, 2(galectin 2) /DB_XREF=gi:5729902 /UG=Hs.113987 lectin, galactoside-binding, soluble, 2 (galectin 2) /FL=gb:M87842.1 gb:NM_006498.1 NM_006498 lectin, galactoside-binding, soluble, 2 LGALS2 3957 NM_006498 0016936 // galactoside binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 208451_s_at NM_000592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000592.2 /DEF=Homo sapiens complement component 4B (C4B), mRNA. /FEA=CDS /GEN=C4B /PROD=complement component 4B /DB_XREF=gi:5579450 /UG=Hs.278625 complement component 4B /FL=gb:NM_000592.2 NM_000592 complement component 4A (Rodgers blood group) /// complement component 4B (Chido blood group) /// complement component 4B (Chido blood group), copy 2 C4A /// C4B /// C4B_2 720 /// 721 /// 100293534 NM_001002029 /// NM_001242823 /// NM_001252204 /// NM_007293 /// XM_006725947 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006956 // complement activation // inferred from genetic interaction /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0008228 // opsonization // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0032490 // detection of molecule of bacterial origin // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 2000427 // positive regulation of apoptotic cell clearance // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0044216 // other organism cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // inferred from direct assay /// 0001849 // complement component C1q binding // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from direct assay 208452_x_at NM_004145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004145.1 /DEF=Homo sapiens myosin IXB (MYO9B), mRNA. /FEA=CDS /GEN=MYO9B /PROD=myosin IXB /DB_XREF=gi:4758749 /UG=Hs.159629 myosin IXB /FL=gb:U42391.1 gb:NM_004145.1 NM_004145 myosin IXB MYO9B 4650 NM_001130065 /// NM_004145 /// XM_005259915 /// XM_006722755 /// XM_006722756 /// XM_006722757 /// XM_006722758 0002548 // monocyte chemotaxis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030048 // actin filament-based movement // traceable author statement /// 0032011 // ARF protein signal transduction // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0032433 // filopodium tip // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 208453_s_at NM_006523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006523.1 /DEF=Homo sapiens X-prolyl aminopeptidase (aminopeptidase P)-like (XPNPEPL), mRNA. /FEA=CDS /GEN=XPNPEPL /PROD=X-prolyl aminopeptidase (aminopeptidase P)-like /DB_XREF=gi:5730117 /UG=Hs.284202 X-prolyl aminopeptidase (aminopeptidase P)-like /FL=gb:NM_006523.1 NM_006523 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble XPNPEP1 7511 NM_001167604 /// NM_020383 /// NR_030724 /// XM_005270144 /// XM_005270145 /// XM_006717962 /// XM_006717963 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010815 // bradykinin catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from direct assay 208454_s_at NM_016134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016134.1 /DEF=Homo sapiens aminopeptidase (LOC51670), mRNA. /FEA=CDS /GEN=LOC51670 /PROD=aminopeptidase /DB_XREF=gi:7706386 /UG=Hs.278993 aminopeptidase /FL=gb:AF107834.1 gb:NM_016134.1 NM_016134 carboxypeptidase Q CPQ 10404 NM_016134 /// XM_005250755 /// XM_006716498 /// XR_428374 0006508 // proteolysis // inferred from direct assay /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0043171 // peptide catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070573 // metallodipeptidase activity // inferred from direct assay 208455_at NM_002855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002855.2 /DEF=Homo sapiens poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) (PVRL1), mRNA. /FEA=CDS /GEN=PVRL1 /PROD=poliovirus receptor-related 1 (herpesvirus entrymediator C; nectin) /DB_XREF=gi:11602905 /UG=Hs.179999 poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) /FL=gb:NM_002855.2 gb:AF060231.1 NM_002855 poliovirus receptor-related 1 (herpesvirus entry mediator C) PVRL1 5818 NM_002855 /// NM_032767 /// NM_203285 /// NM_203286 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002934 // desmosome organization // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0046718 // viral entry into host cell // non-traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // non-traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046790 // virion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 208456_s_at NM_012250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012250.1 /DEF=Homo sapiens oncogene TC21 (TC21), mRNA. /FEA=CDS /GEN=TC21 /PROD=oncogene TC21 /DB_XREF=gi:6912697 /UG=Hs.206097 oncogene TC21 /FL=gb:M31468.1 gb:NM_012250.1 NM_012250 related RAS viral (r-ras) oncogene homolog 2 RRAS2 22800 NM_001102669 /// NM_001177314 /// NM_001177315 /// NM_012250 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 208457_at NM_000815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000815.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, delta (GABRD), mRNA. /FEA=CDS /GEN=GABRD /PROD=gamma-aminobutyric acid (GABA) A receptor,delta /DB_XREF=gi:4557608 /UG=Hs.113882 gamma-aminobutyric acid (GABA) A receptor, delta /FL=gb:AF016917.1 gb:NM_000815.1 NM_000815 gamma-aminobutyric acid (GABA) A receptor, delta GABRD 2563 NM_000815 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 208458_at NM_002978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002978.1 /DEF=Homo sapiens sodium channel, nonvoltage-gated 1, delta (SCNN1D), mRNA. /FEA=CDS /GEN=SCNN1D /PROD=sodium channel, nonvoltage-gated 1, delta /DB_XREF=gi:4506818 /UG=Hs.112842 sodium channel, nonvoltage-gated 1, delta /FL=gb:U38254.1 gb:NM_002978.1 NM_002978 sodium channel, non-voltage-gated 1, delta subunit SCNN1D 6339 NM_001130413 /// NM_002978 /// NR_037668 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from electronic annotation 208459_s_at NM_015024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015024.1 /DEF=Homo sapiens RAN binding protein 16 (RANBP16), mRNA. /FEA=CDS /GEN=RANBP16 /PROD=RAN binding protein 16 /DB_XREF=gi:11999173 /UG=Hs.172685 RAN binding protein 16 /FL=gb:NM_015024.1 gb:AF064729.1 NM_015024 exportin 7 XPO7 23039 NM_001100161 /// NM_001100162 /// NM_015024 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005049 // nuclear export signal receptor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation 208460_at NM_005497 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005497.1 /DEF=Homo sapiens gap junction protein, alpha 7, 45kD (connexin 45) (GJA7), mRNA. /FEA=CDS /GEN=GJA7 /PROD=gap junction protein, alpha 7, 45kD (connexin45) /DB_XREF=gi:4885168 /UG=Hs.138959 gap junction protein, alpha 7, 45kD (connexin 45) /FL=gb:NM_005497.1 NM_005497 gap junction protein, gamma 1, 45kDa GJC1 10052 NM_001080383 /// NM_005497 /// XM_005256920 /// XM_005256921 0001570 // vasculogenesis // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0016264 // gap junction assembly // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0086014 // atrial cardiac muscle cell action potential // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005921 // gap junction // traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005243 // gap junction channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208461_at NM_006497 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006497.1 /DEF=Homo sapiens hypermethylated in cancer 1 (HIC1), mRNA. /FEA=CDS /GEN=HIC1 /PROD=hypermethylated in cancer 1 /DB_XREF=gi:5729870 /UG=Hs.72956 hypermethylated in cancer 1 /FL=gb:NM_006497.1 NM_006497 hypermethylated in cancer 1 HIC1 3090 NM_001098202 /// NM_006497 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208462_s_at NM_005691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005691.1 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 9 (ABCC9), transcript variant SUR2A, mRNA. /FEA=CDS /GEN=ABCC9 /PROD=ATP-binding cassette, sub-family C, member 9,isoform SUR2A /DB_XREF=gi:5032134 /UG=Hs.248960 ATP-binding cassette, sub-family C (CFTRMRP), member 9 /FL=gb:NM_005691.1 NM_005691 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 ABCC9 10060 NM_005691 /// NM_020297 /// NM_020298 /// XM_005253284 /// XM_005253286 /// XM_005253287 /// XM_005253288 /// XM_005253289 /// XM_005253290 /// XM_005253291 /// XM_006719025 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0008282 // ATP-sensitive potassium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008281 // sulfonylurea receptor activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 208463_at NM_000809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000809.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), mRNA. /FEA=CDS /GEN=GABRA4 /PROD=gamma-aminobutyric acid A receptor, alpha 4precursor /DB_XREF=gi:4557604 /UG=Hs.248112 gamma-aminobutyric acid (GABA) A receptor, alpha 4 /FL=gb:NM_000809.1 gb:U30461.1 NM_000809 gamma-aminobutyric acid (GABA) A receptor, alpha 4 GABRA4 2557 NM_000809 /// NM_001204266 /// NM_001204267 /// XM_006714003 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 2001023 // regulation of response to drug // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // traceable author statement 208464_at NM_000829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000829.1 /DEF=Homo sapiens glutamate receptor, ionotrophic, AMPA 4 (GRIA4), mRNA. /FEA=CDS /GEN=GRIA4 /PROD=glutamate receptor, ionotrophic /DB_XREF=gi:4557630 /UG=Hs.163697 glutamate receptor, ionotrophic, AMPA 4 /FL=gb:NM_000829.1 gb:U16129.1 NM_000829 glutamate receptor, ionotropic, AMPA 4 GRIA4 2893 NM_000829 /// NM_001077243 /// NM_001077244 /// NM_001112812 /// NR_046356 /// XM_005271518 /// XM_006718823 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0032983 // kainate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from sequence or structural similarity /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from sequence or structural similarity 208465_at NM_000839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000839.1 /DEF=Homo sapiens glutamate receptor, metabotropic 2 (GRM2), mRNA. /FEA=CDS /GEN=GRM2 /PROD=glutamate receptor, metabotropic 2 precursor /DB_XREF=gi:4504136 /UG=Hs.121510 glutamate receptor, metabotropic 2 /FL=gb:NM_000839.1 gb:L35318.1 NM_000839 glutamate receptor, metabotropic 2 GRM2 2912 NM_000839 /// NM_001130063 /// XM_006713121 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0001641 // group II metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // traceable author statement 208466_at NM_004283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004283.1 /DEF=Homo sapiens RAB3D, member RAS oncogene family (RAB3D), mRNA. /FEA=CDS /GEN=RAB3D /PROD=RAB3D, member RAS oncogene family /DB_XREF=gi:4758999 /UG=Hs.251376 RAB3D, member RAS oncogene family /FL=gb:AF081353.1 gb:NM_004283.1 NM_004283 RAB3D, member RAS oncogene family RAB3D 9545 NM_004283 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0042588 // zymogen granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation 208467_at NM_007249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007249.1 /DEF=Homo sapiens Kruppel-like factor 12 (KLF12), mRNA. /FEA=CDS /GEN=KLF12 /PROD=Kruppel-like factor 12 /DB_XREF=gi:6005712 /UG=Hs.23510 Kruppel-like factor 12 /FL=gb:NM_007249.1 NM_007249 Kruppel-like factor 12 KLF12 11278 NM_007249 /// NM_016285 /// XM_005266251 /// XM_005266252 /// XM_006719762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208468_at NM_007084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007084.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 21 (SOX21), mRNA. /FEA=CDS /GEN=SOX21 /PROD=SRY (sex determining region Y)-box 21 /DB_XREF=gi:5902107 /UG=Hs.187577 SRY (sex determining region Y)-box 21 /FL=gb:NM_007084.1 NM_007084 SRY (sex determining region Y)-box 21 SOX21 11166 NM_007084 0001942 // hair follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0042633 // hair cycle // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity 208469_s_at NM_030652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030652.1 /DEF=Homo sapiens NG3 protein (NG3), mRNA. /FEA=CDS /GEN=NG3 /PROD=NG3 protein /DB_XREF=gi:13449286 /UG=Hs.332138 NG3 protein /FL=gb:NM_030652.1 NM_030652 EGF-like-domain, multiple 8 /// palmitoyl-protein thioesterase 2 /// PPT2-EGFL8 readthrough (NMD candidate) EGFL8 /// PPT2 /// PPT2-EGFL8 9374 /// 80864 /// 100532746 NM_001204103 /// NM_005155 /// NM_030652 /// NM_138717 /// NM_138934 /// NR_037860 /// NR_037861 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008474 // palmitoyl-(protein) hydrolase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // non-traceable author statement 208470_s_at NM_020995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020995.1 /DEF=Homo sapiens haptoglobin-related protein (HPR), mRNA. /FEA=CDS /GEN=HPR /PROD=haptoglobin-related protein /DB_XREF=gi:10337588 /UG=Hs.328822 haptoglobin-related protein /FL=gb:NM_020995.1 NM_020995 haptoglobin /// haptoglobin-related protein HP /// HPR 3240 /// 3250 NM_001126102 /// NM_005143 /// NM_020995 /// XM_005255922 /// XM_006721186 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006952 // defense response // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0051354 // negative regulation of oxidoreductase activity // inferred from direct assay /// 2000296 // negative regulation of hydrogen peroxide catabolic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0030492 // hemoglobin binding // non-traceable author statement 208471_at NM_020995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020995.1 /DEF=Homo sapiens haptoglobin-related protein (HPR), mRNA. /FEA=CDS /GEN=HPR /PROD=haptoglobin-related protein /DB_XREF=gi:10337588 /UG=Hs.328822 haptoglobin-related protein /FL=gb:NM_020995.1 NM_020995 haptoglobin-related protein HPR 3250 NM_020995 /// XM_006721186 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0030492 // hemoglobin binding // non-traceable author statement 208472_at NM_022465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022465.1 /DEF=Homo sapiens zinc finger transcription factor Eos (EOS), mRNA. /FEA=CDS /GEN=EOS /PROD=zinc finger transcription factor Eos /DB_XREF=gi:11968010 /UG=Hs.302031 zinc finger protein, subfamily 1A, 4 (Eos) /FL=gb:AF230809.1 gb:NM_022465.1 NM_022465 IKAROS family zinc finger 4 (Eos) IKZF4 64375 NM_022465 /// XM_005269086 /// XM_005269087 /// XM_005269089 /// XM_005269090 /// XM_005269091 /// XM_005269092 /// XM_005269093 /// XM_005269096 /// XM_006719561 /// XM_006719562 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208473_s_at NM_016295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016295.1 /DEF=Homo sapiens pancreatic zymogen granule membrane associated protein GP2 beta form (LOC51724), mRNA. /FEA=CDS /GEN=LOC51724 /PROD=pancreatic zymogen granule membrane associatedprotein GP2 beta form /DB_XREF=gi:7706490 /UG=Hs.274493 pancreatic zymogen granule membrane associated protein GP2 beta form /FL=gb:D38225.1 gb:AB035542.1 gb:NM_016295.1 NM_016295 glycoprotein 2 (zymogen granule membrane) GP2 2813 NM_001007240 /// NM_001007241 /// NM_001007242 /// NM_001502 /// XM_005255259 /// XM_005255261 /// XR_429676 0002412 // antigen transcytosis by M cells in mucosal-associated lymphoid tissue // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003823 // antigen binding // inferred from electronic annotation 208474_at NM_021195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021195.1 /DEF=Homo sapiens claudin 6 (CLDN6), mRNA. /FEA=CDS /GEN=CLDN6 /PROD=claudin 6 /DB_XREF=gi:11141862 /UG=Hs.247902 claudin 6 /FL=gb:NM_021195.1 gb:AF125306.1 NM_021195 claudin 6 CLDN6 9074 NM_021195 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 208475_at NM_018027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018027.1 /DEF=Homo sapiens hypothetical protein FLJ10210 (FLJ10210), mRNA. /FEA=CDS /GEN=FLJ10210 /PROD=hypothetical protein FLJ10210 /DB_XREF=gi:8922286 /UG=Hs.183639 hypothetical protein FLJ10210 /FL=gb:NM_018027.1 NM_018027 FERM domain containing 4A FRMD4A 55691 NM_018027 /// XM_005252489 /// XM_005252490 /// XM_005252494 /// XM_005252495 /// XM_006717457 /// XM_006717458 /// XM_006717459 /// XM_006717460 /// XM_006717461 /// XM_006717462 /// XM_006717463 /// XM_006717464 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation 0030674 // protein binding, bridging // inferred from electronic annotation 208476_s_at NM_018027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018027.1 /DEF=Homo sapiens hypothetical protein FLJ10210 (FLJ10210), mRNA. /FEA=CDS /GEN=FLJ10210 /PROD=hypothetical protein FLJ10210 /DB_XREF=gi:8922286 /UG=Hs.183639 hypothetical protein FLJ10210 /FL=gb:NM_018027.1 NM_018027 FERM domain containing 4A FRMD4A 55691 NM_018027 /// XM_005252489 /// XM_005252490 /// XM_005252494 /// XM_005252495 /// XM_006717457 /// XM_006717458 /// XM_006717459 /// XM_006717460 /// XM_006717461 /// XM_006717462 /// XM_006717463 /// XM_006717464 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation 0030674 // protein binding, bridging // inferred from electronic annotation 208477_at NM_004976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004976.1 /DEF=Homo sapiens potassium voltage-gated channel, Shaw-related subfamily, member 1 (KCNC1), mRNA. /FEA=CDS /GEN=KCNC1 /PROD=potassium voltage-gated channel, Shaw-relatedsubfamily, member 1 /DB_XREF=gi:4826785 /UG=Hs.181768 potassium voltage-gated channel, Shaw-related subfamily, member 1 /FL=gb:NM_004976.1 NM_004976 potassium voltage-gated channel, Shaw-related subfamily, member 1 KCNC1 3746 NM_001112741 /// NM_004976 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208478_s_at NM_004324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004324.1 /DEF=Homo sapiens BCL2-associated X protein (BAX), mRNA. /FEA=CDS /GEN=BAX /PROD=BCL2-associated X protein /DB_XREF=gi:4757837 /UG=Hs.159428 BCL2-associated X protein /FL=gb:L22474.1 gb:NM_004324.1 NM_004324 BCL2-associated X protein BAX 581 NM_001291428 /// NM_001291429 /// NM_001291430 /// NM_001291431 /// NM_004324 /// NM_138761 /// NM_138762 /// NM_138763 /// NM_138764 /// NR_027882 /// XM_006723313 /// XM_006723314 0001101 // response to acid // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001777 // T cell homeostatic proliferation // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from direct assay /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0001844 // protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0002352 // B cell negative selection // inferred from electronic annotation /// 0002358 // B cell homeostatic proliferation // inferred from electronic annotation /// 0002904 // positive regulation of B cell apoptotic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006927 // transformed cell apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred by curator /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0009566 // fertilization // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010248 // establishment or maintenance of transmembrane electrochemical gradient // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from electronic annotation /// 0032976 // release of matrix enzymes from mitochondria // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from physical interaction /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048515 // spermatid differentiation // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation /// 1902263 // apoptotic process involved in embryonic digit morphogenesis // inferred from electronic annotation /// 1902512 // positive regulation of apoptotic DNA fragmentation // inferred from mutant phenotype /// 1990009 // retinal cell apoptotic process // inferred from mutant phenotype /// 1990117 // B cell receptor apoptotic signaling pathway // inferred from direct assay /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005757 // mitochondrial permeability transition pore complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097136 // Bcl-2 family protein complex // inferred from direct assay /// 0097144 // BAX complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0015267 // channel activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from direct assay /// 0051434 // BH3 domain binding // inferred from physical interaction 208479_at NM_000217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000217.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), mRNA. /FEA=CDS /GEN=KCNA1 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 1 /DB_XREF=gi:4557684 /UG=Hs.60843 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) /FL=gb:L02750.1 gb:NM_000217.1 NM_000217 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) KCNA1 3736 NM_000217 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015079 // potassium ion transmembrane transporter activity // traceable author statement 208480_s_at NM_001171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001171.2 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 6 (ABCC6), mRNA. /FEA=CDS /GEN=ABCC6 /PROD=ATP-binding cassette, sub-family C, member 6 /DB_XREF=gi:6715560 /UG=Hs.274260 ATP-binding cassette, sub-family C (CFTRMRP), member 6 /FL=gb:AF076622.1 gb:NM_001171.2 NM_001171 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 /// multidrug resistance-associated protein 6-like ABCC6 /// LOC101930322 368 /// 101930322 NM_001079528 /// NM_001171 /// XM_005255310 /// XM_005276048 /// XM_006725193 /// XM_006725194 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208481_at NM_016116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016116.1 /DEF=Homo sapiens ASB-4 protein (LOC51666), mRNA. /FEA=CDS /GEN=LOC51666 /PROD=ASB-4 protein /DB_XREF=gi:7706378 /UG=Hs.248062 ASB-4 protein /FL=gb:AF156779.1 gb:NM_016116.1 NM_016116 ankyrin repeat and SOCS box containing 4 ASB4 51666 NM_016116 /// NM_145872 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from electronic annotation /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 208482_at NM_001049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001049.1 /DEF=Homo sapiens somatostatin receptor 1 (SSTR1), mRNA. /FEA=CDS /GEN=SSTR1 /PROD=somatostatin receptor 1 /DB_XREF=gi:4557856 /UG=Hs.248160 somatostatin receptor 1 /FL=gb:NM_001049.1 NM_001049 somatostatin receptor 1 SSTR1 6751 NM_001049 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007215 // glutamate receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 208483_x_at NM_004138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004138.1 /DEF=Homo sapiens keratin, hair, acidic,3A (KRTHA3A), mRNA. /FEA=CDS /GEN=KRTHA3A /PROD=type I hair keratin 3A /DB_XREF=gi:4758659 /UG=Hs.197874 keratin, hair, acidic,3A /FL=gb:NM_004138.1 NM_004138 keratin 33A KRT33A 3883 NM_004138 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 208484_at NM_005325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005325.1 /DEF=Homo sapiens H1 histone family, member 1 (H1F1), mRNA. /FEA=CDS /GEN=H1F1 /PROD=H1 histone family, member 1 /DB_XREF=gi:4885372 /UG=Hs.150206 H1 histone family, member 1 /FL=gb:NM_005325.1 NM_005325 histone cluster 1, H1a HIST1H1A 3024 NM_005325 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from mutant phenotype 208485_x_at NM_003879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003879.1 /DEF=Homo sapiens CASP8 and FADD-like apoptosis regulator (CFLAR), mRNA. /FEA=CDS /GEN=CFLAR /PROD=CASP8 and FADD-like apoptosis regulator /DB_XREF=gi:4505246 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF041462.1 gb:NM_003879.1 NM_003879 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 208486_at NM_000798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000798.1 /DEF=Homo sapiens dopamine receptor D5 (DRD5), mRNA. /FEA=CDS /GEN=DRD5 /PROD=dopamine receptor D5 /DB_XREF=gi:4503390 /UG=Hs.143526 dopamine receptor D5 /FL=gb:NM_000798.1 NM_000798 dopamine receptor D5 DRD5 1816 NM_000798 0001963 // synaptic transmission, dopaminergic // non-traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0045762 // positive regulation of adenylate cyclase activity // non-traceable author statement /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045924 // regulation of female receptivity // inferred from electronic annotation /// 0046960 // sensitization // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // traceable author statement /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0001588 // dopamine neurotransmitter receptor activity, coupled via Gs // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from direct assay /// 0035240 // dopamine binding // inferred from direct assay 208487_at NM_002316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002316.1 /DEF=Homo sapiens LIM homeobox transcription factor 1, beta (LMX1B), mRNA. /FEA=CDS /GEN=LMX1B /PROD=LIM homeobox transcription factor 1, beta /DB_XREF=gi:4505006 /UG=Hs.133709 LIM homeobox transcription factor 1, beta /FL=gb:AF057135.1 gb:NM_002316.1 NM_002316 LIM homeobox transcription factor 1, beta LMX1B 4010 NM_001174146 /// NM_001174147 /// NM_002316 0001701 // in utero embryonic development // non-traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208488_s_at NM_000651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000651.1 /DEF=Homo sapiens complement component (3b4b) receptor 1, including Knops blood group system (CR1), mRNA. /FEA=CDS /GEN=CR1 /PROD=complement component (3b4b) receptor 1,including Knops blood group system /DB_XREF=gi:10834995 /UG=Hs.193716 complement component (3b4b) receptor 1, including Knops blood group system /FL=gb:NM_000651.1 NM_000651 complement component (3b/4b) receptor 1 (Knops blood group) CR1 1378 NM_000573 /// NM_000651 /// XM_005273064 /// XM_006711166 /// XM_006711167 /// XM_006711168 0002376 // immune system process // inferred from electronic annotation /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045957 // negative regulation of complement activation, alternative pathway // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900005 // positive regulation of serine-type endopeptidase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001851 // complement component C3b binding // inferred from direct assay /// 0001855 // complement component C4b binding // inferred from direct assay /// 0001861 // complement component C4b receptor activity // inferred from direct assay /// 0004877 // complement component C3b receptor activity // inferred from direct assay 208489_at NM_005267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005267.1 /DEF=Homo sapiens gap junction protein, alpha 8, 50kD (connexin 50) (GJA8), mRNA. /FEA=CDS /GEN=GJA8 /PROD=gap junction protein, alpha 8, 50kD (connexin50) /DB_XREF=gi:4885274 /UG=Hs.157433 gap junction protein, alpha 8, 50kD (connexin 50) /FL=gb:NM_005267.1 NM_005267 gap junction protein, alpha 8, 50kDa GJA8 2703 NM_005267 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0015267 // channel activity // traceable author statement 208490_x_at NM_003522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003522.1 /DEF=Homo sapiens H2B histone family, member G (H2BFG), mRNA. /FEA=CDS /GEN=H2BFG /PROD=H2B histone family, member G /DB_XREF=gi:4504264 /UG=Hs.182137 H2B histone family, member G /FL=gb:NM_003522.1 NM_003522 histone cluster 1, H2bc /// histone cluster 1, H2be /// histone cluster 1, H2bf /// histone cluster 1, H2bg /// histone cluster 1, H2bi HIST1H2BC /// HIST1H2BE /// HIST1H2BF /// HIST1H2BG /// HIST1H2BI 8339 /// 8343 /// 8344 /// 8346 /// 8347 NM_003518 /// NM_003522 /// NM_003523 /// NM_003525 /// NM_003526 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208491_s_at NM_021965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021965.1 /DEF=Homo sapiens phosphoglucomutase 5 (PGM5), mRNA. /FEA=CDS /GEN=PGM5 /PROD=phosphoglucomutase 5 /DB_XREF=gi:11415049 /UG=Hs.167473 phosphoglucomutase 5 /FL=gb:NM_021965.1 NM_021965 phosphoglucomutase 5 PGM5 5239 NM_021965 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // not recorded /// 0006006 // glucose metabolic process // not recorded /// 0007155 // cell adhesion // inferred from electronic annotation /// 0019388 // galactose catabolic process // not recorded 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005914 // spot adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // not recorded /// 0016010 // dystrophin-associated glycoprotein complex // inferred from sequence or structural similarity /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004614 // phosphoglucomutase activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208492_at NM_000538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000538.1 /DEF=Homo sapiens regulatory factor X-associated protein (RFXAP), mRNA. /FEA=CDS /GEN=RFXAP /PROD=regulatory factor X-associated protein /DB_XREF=gi:4506500 /UG=Hs.24422 regulatory factor X-associated protein /FL=gb:NM_000538.1 NM_000538 regulatory factor X-associated protein RFXAP 5994 NM_000538 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement 208493_at NM_005523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005523.3 /DEF=Homo sapiens homeo box A11 (HOXA11), mRNA. /FEA=CDS /GEN=HOXA11 /PROD=homeo box A11 /DB_XREF=gi:7524012 /UG=Hs.249171 homeo box A11 /FL=gb:NM_005523.3 NM_005523 homeobox A11 HOXA11 3207 NM_005523 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001759 // organ induction // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0007501 // mesodermal cell fate specification // inferred from sequence or structural similarity /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010720 // positive regulation of cell development // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208494_at NM_014228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014228.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 (SLC6A7), mRNA. /FEA=CDS /GEN=SLC6A7 /PROD=solute carrier family 6 (neurotransmittertransporter, L-proline), member 7 /DB_XREF=gi:7657588 /UG=Hs.241597 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 /FL=gb:NM_014228.1 NM_014228 solute carrier family 6 (neurotransmitter transporter), member 7 SLC6A7 6534 NM_014228 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015824 // proline transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 208495_at NM_021025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021025.1 /DEF=Homo sapiens homeo box 11-like 2 (TLX3), mRNA. /FEA=CDS /GEN=TLX3 /PROD=homeo box 11-like 2 /DB_XREF=gi:10440563 /UG=Hs.249125 homeo box 11-like 2 /FL=gb:NM_021025.1 NM_021025 T-cell leukemia homeobox 3 TLX3 30012 NM_021025 0001708 // cell fate specification // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208496_x_at NM_003534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003534.1 /DEF=Homo sapiens H3 histone family, member H (H3FH), mRNA. /FEA=CDS /GEN=H3FH /PROD=H3 histone family, member H /DB_XREF=gi:4504290 /UG=Hs.247813 H3 histone family, member H /FL=gb:NM_003534.1 NM_003534 histone cluster 1, H3g HIST1H3G 8355 NM_003534 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208497_x_at NM_006161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006161.1 /DEF=Homo sapiens neurogenin 1 (NEUROG1), mRNA. /FEA=CDS /GEN=NEUROG1 /PROD=neurogenin 1 /DB_XREF=gi:5453769 /UG=Hs.248149 neurogenin 1 /FL=gb:NM_006161.1 NM_006161 neurogenin 1 NEUROG1 4762 NM_006161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031536 // positive regulation of exit from mitosis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 208498_s_at NM_004038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004038.1 /DEF=Homo sapiens amylase, alpha 1A; salivary (AMY1A), mRNA. /FEA=CDS /GEN=AMY1A /PROD=amylase, alpha 1A; salivary /DB_XREF=gi:4757749 /UG=Hs.274376 amylase, alpha 1A; salivary /FL=gb:NM_004038.1 NM_004038 actin, gamma 1 pseudogene 4 /// amylase, alpha 1A (salivary) /// amylase, alpha 1B (salivary) /// amylase, alpha 1C (salivary) /// amylase, alpha 2A (pancreatic) /// amylase, alpha 2B (pancreatic) ACTG1P4 /// AMY1A /// AMY1B /// AMY1C /// AMY2A /// AMY2B 276 /// 277 /// 278 /// 279 /// 280 /// 648740 NM_000699 /// NM_001008218 /// NM_001008219 /// NM_001008221 /// NM_004038 /// NM_020978 /// NR_024438 /// XM_005270755 /// XM_005270758 /// XM_005270761 /// XM_006710579 /// XM_006710580 /// XM_006710581 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016052 // carbohydrate catabolic process // inferred from direct assay /// 0044245 // polysaccharide digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004556 // alpha-amylase activity // inferred from electronic annotation /// 0004556 // alpha-amylase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from direct assay /// 0043169 // cation binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208499_s_at NM_006260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006260.1 /DEF=Homo sapiens protein-kinase, interferon-inducible double stranded RNA dependent inhibitor (PRKRI), mRNA. /FEA=CDS /GEN=PRKRI /PROD=protein-kinase, interferon-inducible doublestranded RNA dependent inhibitor /DB_XREF=gi:5453979 /UG=Hs.9683 DnaJ (Hsp40) homolog, subfamily C, member 3 /FL=gb:U28424.1 gb:NM_006260.1 NM_006260 DnaJ (Hsp40) homolog, subfamily C, member 3 DNAJC3 5611 NM_006260 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031205 // endoplasmic reticulum Sec complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051787 // misfolded protein binding // inferred from electronic annotation 208500_x_at NM_012183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012183.1 /DEF=Homo sapiens forkhead box D3 (FOXD3), mRNA. /FEA=CDS /GEN=FOXD3 /PROD=forkhead box D3 /DB_XREF=gi:6912371 /UG=Hs.253766 forkhead box D3 /FL=gb:NM_012183.1 NM_012183 forkhead box D3 FOXD3 27022 NM_012183 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // not recorded /// 0001822 // kidney development // not recorded /// 0001829 // trophectodermal cell differentiation // not recorded /// 0001892 // embryonic placenta development // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007422 // peripheral nervous system development // not recorded /// 0030318 // melanocyte differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048484 // enteric nervous system development // not recorded /// 0048485 // sympathetic nervous system development // not recorded /// 0048846 // axon extension involved in axon guidance // not recorded /// 0048937 // lateral line nerve glial cell development // not recorded /// 0050935 // iridophore differentiation // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051216 // cartilage development // not recorded 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // not recorded 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 208501_at NM_004188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004188.1 /DEF=Homo sapiens growth factor independent 1B (potential regulator of CDKN1A, translocated in CML) (GFI1B), mRNA. /FEA=CDS /GEN=GFI1B /PROD=growth factor independent 1B (potentialregulator of CDKN1A, translocated in CML) /DB_XREF=gi:4758427 /UG=Hs.249229 growth factor independent 1B (potential regulator of CDKN1A, translocated in CML) /FL=gb:AF081946.1 gb:NM_004188.1 NM_004188 growth factor independent 1B transcription repressor GFI1B 8328 NM_001135031 /// NM_004188 /// XM_006717297 /// XM_006717298 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208502_s_at NM_002653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002653.1 /DEF=Homo sapiens paired-like homeodomain transcription factor 1 (PITX1), mRNA. /FEA=CDS /GEN=PITX1 /PROD=paired-like homeodomain transcription factor 1 /DB_XREF=gi:4505824 /UG=Hs.84136 paired-like homeodomain transcription factor 1 /FL=gb:NM_002653.1 NM_002653 paired-like homeodomain 1 PITX1 5307 NM_002653 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014707 // branchiomeric skeletal muscle development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208503_s_at NM_021167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021167.1 /DEF=Homo sapiens hypothetical protein WUGSC:H_RG083M05.2 (LOC57798), mRNA. /FEA=CDS /GEN=LOC57798 /PROD=hypothetical protein WUGSC:H_RG083M05.2 /DB_XREF=gi:10863962 /UG=Hs.296445 hypothetical protein WUGSC:H_RG083M05.2 /FL=gb:NM_021167.1 NM_021167 GATA zinc finger domain containing 1 GATAD1 57798 NM_021167 /// NR_052016 /// XR_428181 /// XR_428182 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208504_x_at NM_018931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018931.1 /DEF=Homo sapiens protocadherin beta 11 (PCDHB11), mRNA. /FEA=CDS /GEN=PCDHB11 /PROD=protocadherin beta 11 /DB_XREF=gi:9256603 /UG=Hs.283084 protocadherin beta 11 /FL=gb:AF152490.1 gb:NM_018931.1 NM_018931 protocadherin beta 11 PCDHB11 56125 NM_018931 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 208505_s_at NM_000511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000511.1 /DEF=Homo sapiens fucosyltransferase 2 (secretor status included) (FUT2), mRNA. /FEA=CDS /GEN=FUT2 /PROD=fucosyltransferase 2 (secretor status included) /DB_XREF=gi:4503806 /UG=Hs.46328 fucosyltransferase 2 (secretor status included) /FL=gb:NM_000511.1 NM_000511 fucosyltransferase 2 (secretor status included) FUT2 2524 NM_000511 /// NM_001097638 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // traceable author statement /// 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 208506_at NM_021018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021018.1 /DEF=Homo sapiens H3 histone family, member I (H3FI), mRNA. /FEA=CDS /GEN=H3FI /PROD=H3 histone family, member I /DB_XREF=gi:10440559 /UG=Hs.247814 H3 histone family, member I /FL=gb:NM_021018.1 NM_021018 histone cluster 1, H3f HIST1H3F 8968 NM_021018 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208507_at NM_012377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012377.1 /DEF=Homo sapiens olfactory receptor, family 7, subfamily C, member 2 (OR7C2), mRNA. /FEA=CDS /GEN=OR7C2 /PROD=olfactory receptor, family 7, subfamily C,member 3 /DB_XREF=gi:13624324 /FL=gb:NM_012377.1 NM_012377 olfactory receptor, family 7, subfamily C, member 2 OR7C2 26658 NM_012377 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208508_s_at NM_030905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030905.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily J, member 2 (OR2J2), mRNA. /FEA=CDS /GEN=OR2J2 /PROD=olfactory receptor, family 2, subfamily J,member 2 /DB_XREF=gi:13624330 /FL=gb:NM_030905.1 NM_030905 olfactory receptor, family 2, subfamily J, member 2 OR2J2 26707 NM_030905 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208509_s_at NM_030901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030901.1 /DEF=Homo sapiens olfactory receptor, family 7, subfamily A, member 17 (OR7A17), mRNA. /FEA=CDS /GEN=OR7A17 /PROD=olfactory receptor, family 7, subfamily A,member 17 /DB_XREF=gi:13775161 /FL=gb:NM_030901.1 NM_030901 olfactory receptor, family 7, subfamily A, member 17 OR7A17 26333 NM_030901 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208510_s_at NM_015869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015869.1 /DEF=Homo sapiens peroxisome proliferative activated receptor, gamma (PPARG), mRNA. /FEA=CDS /GEN=PPARG /PROD=peroxisome proliferative activated receptorgamma, isoform 2 /DB_XREF=gi:7705548 /UG=Hs.100724 peroxisome proliferative activated receptor, gamma /FL=gb:D83233.1 gb:U63415.1 gb:U79012.1 gb:NM_015869.1 NM_015869 peroxisome proliferator-activated receptor gamma PPARG 5468 NM_005037 /// NM_015869 /// NM_138711 /// NM_138712 /// XM_006713208 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from sequence or structural similarity /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010871 // negative regulation of receptor biosynthetic process // inferred from direct assay /// 0010887 // negative regulation of cholesterol storage // inferred from direct assay /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033993 // response to lipid // inferred from sequence or structural similarity /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0042953 // lipoprotein transport // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045713 // low-density lipoprotein particle receptor biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046321 // positive regulation of fatty acid oxidation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051974 // negative regulation of telomerase activity // inferred from electronic annotation /// 0055088 // lipid homeostasis // traceable author statement /// 0055098 // response to low-density lipoprotein particle // inferred from direct assay /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from mutant phenotype /// 0060694 // regulation of cholesterol transporter activity // inferred by curator /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004955 // prostaglandin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from direct assay /// 0050544 // arachidonic acid binding // inferred from sequence or structural similarity 208511_at NM_021000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021000.1 /DEF=Homo sapiens pituitary tumor-transforming 3 (PTTG3), mRNA. /FEA=CDS /GEN=PTTG3 /PROD=pituitary tumor-transforming 3 /DB_XREF=gi:10337606 /UG=Hs.247762 pituitary tumor-transforming 3 /FL=gb:NM_021000.1 gb:AF095289.1 NM_021000 pituitary tumor-transforming 3, pseudogene PTTG3P 26255 NR_002734 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0017124 // SH3 domain binding // inferred from electronic annotation 208512_s_at NM_005936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005936.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 (MLLT4), mRNA. /FEA=CDS /GEN=MLLT4 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 4 /DB_XREF=gi:5174574 /UG=Hs.100469 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 /FL=gb:U02478.1 gb:NM_005936.1 NM_005936 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 MLLT4 4301 NM_001040000 /// NM_001040001 /// NM_001207008 /// NM_001291964 /// NM_005936 /// XM_005266996 /// XM_005266997 /// XM_006715483 /// XM_006715484 /// XM_006715485 /// XM_006715486 /// XM_006715487 /// XM_006715488 /// XM_006715489 /// XM_006715490 /// XM_006715491 /// XM_006715492 /// XM_006715493 /// XM_006715494 /// XR_427971 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 208513_at NM_012182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012182.1 /DEF=Homo sapiens forkhead box B1 (FOXB1), mRNA. /FEA=CDS /GEN=FOXB1 /PROD=forkhead box B1 /DB_XREF=gi:11386194 /UG=Hs.247756 forkhead box B1 /FL=gb:NM_012182.1 gb:AF071554.1 NM_012182 forkhead box B1 FOXB1 27023 NM_012182 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007389 // pattern specification process // not recorded /// 0007412 // axon target recognition // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021767 // mammillary body development // inferred from sequence or structural similarity /// 0021794 // thalamus development // inferred from electronic annotation /// 0021855 // hypothalamus cell migration // inferred from sequence or structural similarity /// 0022029 // telencephalon cell migration // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0033504 // floor plate development // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0048513 // organ development // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061374 // mammillothalamic axonal tract development // inferred from sequence or structural similarity /// 0061377 // mammary gland lobule development // inferred from sequence or structural similarity /// 0061379 // inferior colliculus development // inferred from sequence or structural similarity /// 0061381 // cell migration in diencephalon // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 208514_at NM_000219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000219.1 /DEF=Homo sapiens potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), mRNA. /FEA=CDS /GEN=KCNE1 /PROD=potassium voltage-gated channel, Isk-relatedfamily, member 1 /DB_XREF=gi:4557686 /UG=Hs.121495 potassium voltage-gated channel, Isk-related family, member 1 /FL=gb:L28168.1 gb:NM_000219.1 gb:AF135188.1 NM_000219 potassium voltage-gated channel, Isk-related family, member 1 KCNE1 3753 NM_000219 /// NM_001127668 /// NM_001127669 /// NM_001127670 /// NM_001270402 /// NM_001270403 /// NM_001270404 /// NM_001270405 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071435 // potassium ion export // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086009 // membrane repolarization // inferred from direct assay /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090315 // negative regulation of protein targeting to membrane // inferred from electronic annotation /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902259 // regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0031433 // telethonin binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from direct assay /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 208515_at NM_003521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003521.1 /DEF=Homo sapiens H2B histone family, member E (H2BFE), mRNA. /FEA=CDS /GEN=H2BFE /PROD=H2B histone family, member E /DB_XREF=gi:4504262 /UG=Hs.182432 H2B histone family, member E /FL=gb:NM_003521.1 NM_003521 histone cluster 1, H2bm HIST1H2BM 8342 NM_003521 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208516_at NM_005959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005959.1 /DEF=Homo sapiens melatonin receptor 1B (MTNR1B), mRNA. /FEA=CDS /GEN=MTNR1B /PROD=melatonin receptor 1B /DB_XREF=gi:5174594 /UG=Hs.158328 melatonin receptor 1B /FL=gb:NM_005959.1 gb:U25341.1 NM_005959 melatonin receptor 1B MTNR1B 4544 NM_005959 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008502 // melatonin receptor activity // inferred from electronic annotation 208517_x_at NM_001207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001207.1 /DEF=Homo sapiens basic transcription factor 3 (BTF3), mRNA. /FEA=CDS /GEN=BTF3 /PROD=basic transcription factor 3 /DB_XREF=gi:4502464 /UG=Hs.101025 basic transcription factor 3 /FL=gb:NM_001207.1 NM_001207 basic transcription factor 3 BTF3 689 NM_001037637 /// NM_001207 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208518_s_at NM_003894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003894.3 /DEF=Homo sapiens period (Drosophila) homolog 2 (PER2), transcript variant 2, mRNA. /FEA=CDS /GEN=PER2 /PROD=period 2, isoform 1 /DB_XREF=gi:12707560 /UG=Hs.153405 period (Drosophila) homolog 2 /FL=gb:NM_003894.3 gb:AB012614.1 NM_003894 period circadian clock 2 PER2 8864 NM_003894 /// NM_022817 /// XM_005246111 /// XM_006712824 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from sequence or structural similarity /// 0019249 // lactate biosynthetic process // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 0051946 // regulation of glutamate uptake involved in transmission of nerve impulse // inferred from sequence or structural similarity /// 0070345 // negative regulation of fat cell proliferation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from sequence or structural similarity /// 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity 208519_x_at NM_001501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001501.1 /DEF=Homo sapiens gonadotropin-releasing hormone 2 (GNRH2), mRNA. /FEA=CDS /GEN=GNRH2 /PROD=gonadotropin-releasing hormone 2 /DB_XREF=gi:4504056 /UG=Hs.129715 gonadotropin-releasing hormone 2 /FL=gb:NM_001501.1 NM_001501 gonadotropin-releasing hormone 2 GNRH2 2797 NM_001501 /// NM_178331 /// NM_178332 /// XM_006723560 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 208520_at NM_013938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013938.1 /DEF=Homo sapiens olfactory receptor, family 10, subfamily H, member 3 (OR10H3), mRNA. /FEA=CDS /GEN=OR10H3 /PROD=olfactory receptor, family 10, subfamily H,member 3 /DB_XREF=gi:7330338 /UG=Hs.135305 olfactory receptor, family 10, subfamily H, member 3 /FL=gb:NM_013938.1 NM_013938 olfactory receptor, family 10, subfamily H, member 3 OR10H3 26532 NM_013938 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 208521_at NM_006637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006637.1 /DEF=Homo sapiens olfactory receptor, family 5, subfamily I, member 1 (OR5I1), mRNA. /FEA=CDS /GEN=OR5I1 /PROD=olfactory receptor, family 5, subfamily I,member 1 /DB_XREF=gi:5729959 /UG=Hs.159903 olfactory receptor, family 5, subfamily I, member 1 /FL=gb:NM_006637.1 NM_006637 olfactory receptor, family 5, subfamily I, member 1 OR5I1 10798 NM_006637 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208522_s_at NM_000264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000264.1 /DEF=Homo sapiens patched (Drosophila) homolog (PTCH), mRNA. /FEA=CDS /GEN=PTCH /PROD=patched (Drosophila) homolog /DB_XREF=gi:4506246 /UG=Hs.159526 patched (Drosophila) homolog /FL=gb:U59464.1 gb:NM_000264.1 NM_000264 patched 1 PTCH1 5727 NM_000264 /// NM_001083602 /// NM_001083603 /// NM_001083604 /// NM_001083605 /// NM_001083606 /// NM_001083607 /// XM_005252102 /// XR_242599 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021532 // neural tube patterning // inferred from mutant phenotype /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021997 // neural plate axis specification // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061005 // cell differentiation involved in kidney development // inferred from electronic annotation /// 0061053 // somite development // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from expression pattern /// 0072203 // cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0044294 // dendritic growth cone // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072372 // primary cilium // inferred from electronic annotation 0005113 // patched binding // inferred from electronic annotation /// 0005119 // smoothened binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0030332 // cyclin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0097108 // hedgehog family protein binding // inferred from physical interaction 208523_x_at NM_003525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003525.1 /DEF=Homo sapiens H2B histone family, member K (H2BFK), mRNA. /FEA=CDS /GEN=H2BFK /PROD=H2B histone family, member K /DB_XREF=gi:4504270 /UG=Hs.182140 H2B histone family, member K /FL=gb:NM_003525.1 NM_003525 histone cluster 1, H2bc /// histone cluster 1, H2be /// histone cluster 1, H2bf /// histone cluster 1, H2bg /// histone cluster 1, H2bi HIST1H2BC /// HIST1H2BE /// HIST1H2BF /// HIST1H2BG /// HIST1H2BI 8339 /// 8343 /// 8344 /// 8346 /// 8347 NM_003518 /// NM_003522 /// NM_003523 /// NM_003525 /// NM_003526 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208524_at NM_005290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005290.1 /DEF=Homo sapiens G protein-coupled receptor 15 (GPR15), mRNA. /FEA=CDS /GEN=GPR15 /PROD=G protein-coupled receptor 15 /DB_XREF=gi:4885298 /UG=Hs.159900 G protein-coupled receptor 15 /FL=gb:NM_005290.1 NM_005290 G protein-coupled receptor 15 GPR15 2838 NM_005290 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 208525_s_at NM_012369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012369.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily F, member 1 (OR2F1), mRNA. /FEA=CDS /GEN=OR2F1 /PROD=olfactory receptor, family 2, subfamily F,member 1 /DB_XREF=gi:6912557 /UG=Hs.159898 olfactory receptor, family 2, subfamily F, member 1 /FL=gb:NM_012369.1 NM_012369 olfactory receptor, family 2, subfamily F, member 1 /// olfactory receptor, family 2, subfamily F, member 2 OR2F1 /// OR2F2 26211 /// 135948 NM_001004685 /// NM_012369 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208526_at NM_012369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012369.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily F, member 1 (OR2F1), mRNA. /FEA=CDS /GEN=OR2F1 /PROD=olfactory receptor, family 2, subfamily F,member 1 /DB_XREF=gi:6912557 /UG=Hs.159898 olfactory receptor, family 2, subfamily F, member 1 /FL=gb:NM_012369.1 NM_012369 olfactory receptor, family 2, subfamily F, member 1 OR2F1 26211 NM_012369 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208527_x_at NM_003523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003523.1 /DEF=Homo sapiens H2B histone family, member H (H2BFH), mRNA. /FEA=CDS /GEN=H2BFH /PROD=H2B histone family, member H /DB_XREF=gi:4504266 /UG=Hs.182138 H2B histone family, member H /FL=gb:NM_003523.1 NM_003523 histone cluster 1, H2be HIST1H2BE 8344 NM_003523 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208528_x_at NM_021015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021015.1 /DEF=Homo sapiens synovial sarcoma, X breakpoint 5 (SSX5), mRNA. /FEA=CDS /GEN=SSX5 /PROD=synovial sarcoma, X breakpoint 5 /DB_XREF=gi:10337598 /UG=Hs.166198 synovial sarcoma, X breakpoint 5 /FL=gb:NM_021015.1 gb:U90842.1 NM_021015 synovial sarcoma, X breakpoint 3 /// synovial sarcoma, X breakpoint 5 /// synovial sarcoma, X breakpoint 7 SSX3 /// SSX5 /// SSX7 6758 /// 10214 /// 280658 NM_021014 /// NM_021015 /// NM_173358 /// NM_175711 /// NM_175723 /// XM_005262001 /// XM_005272579 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 208529_at NM_001208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001208.1 /DEF=Homo sapiens basic transcription factor 3, like 1 (BTF3L1), mRNA. /FEA=CDS /GEN=BTF3L1 /PROD=basic transcription factor 3, like 1 /DB_XREF=gi:4502466 /UG=Hs.181965 basic transcription factor 3, like 1 /FL=gb:NM_001208.1 NM_001208 basic transcription factor 3 pseudogene 11 BTF3P11 690 NR_026983 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208530_s_at NM_016152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016152.1 /DEF=Homo sapiens retinoic acid receptor, beta (RARB), mRNA. /FEA=CDS /GEN=RARB /PROD=retinoic acid receptor beta 4 /DB_XREF=gi:7706624 /UG=Hs.171495 retinoic acid receptor, beta /FL=gb:AF157483.1 gb:NM_016152.1 NM_016152 retinoic acid receptor, beta RARB 5915 NM_000965 /// NM_001290216 /// NM_001290217 /// NM_001290266 /// NM_001290276 /// NM_001290277 /// NM_001290300 /// NM_016152 /// NR_110892 /// NR_110893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021756 // striatum development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation 208531_at NM_006220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006220.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (SERPINA2), mRNA. /FEA=CDS /GEN=SERPINA2 /PROD=serine (or cysteine) proteinase inhibitor, cladeA (alpha-1 antiproteinase, antitrypsin), member 2 /DB_XREF=gi:5453895 /UG=Hs.184929 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 /FL=gb:NM_006220.1 NM_006220 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) SERPINA2 390502 NM_006220 /// NR_110563 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 208532_x_at NM_021046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021046.1 /DEF=Homo sapiens UHS KerB (LOC57830), mRNA. /FEA=CDS /GEN=LOC57830 /PROD=UHS KerB /DB_XREF=gi:10567823 /UG=Hs.247709 UHS KerB /FL=gb:NM_021046.1 NM_021046 keratin associated protein 5-8 KRTAP5-8 57830 NM_021046 0005576 // extracellular region // non-traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0030280 // structural constituent of epidermis // non-traceable author statement 208533_at NM_005986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005986.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 1 (SOX1), mRNA. /FEA=CDS /GEN=SOX1 /PROD=SRY (sex determining region Y)-box 1 /DB_XREF=gi:5174690 /UG=Hs.211945 SRY (sex determining region Y)-box 1 /FL=gb:NM_005986.1 NM_005986 SRY (sex determining region Y)-box 1 SOX1 6656 NM_005986 0001764 // neuron migration // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0021521 // ventral spinal cord interneuron specification // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208534_s_at NM_006989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006989.1 /DEF=Homo sapiens GTPase activating protein-like (GAPL), mRNA. /FEA=CDS /GEN=GAPL /PROD=GTPase activating protein-like /DB_XREF=gi:5901957 /UG=Hs.184367 GTPase activating protein-like /FL=gb:NM_006989.1 NM_006989 ras GTPase-activating protein 4-like /// RAS p21 protein activator 4 /// RAS p21 protein activator 4B /// RAS p21 protein activator 4C, pseudogene LOC102725198 /// RASA4 /// RASA4B /// RASA4CP 10156 /// 401331 /// 100271927 /// 102725198 NM_001079877 /// NM_001277335 /// NM_006989 /// NR_024116 /// XM_005250084 /// XM_005250085 /// XM_005250104 /// XM_006715828 /// XM_006715829 /// XM_006726443 /// XM_006726444 /// XM_006726445 /// XR_428162 /// XR_428163 /// XR_428164 /// XR_428165 /// XR_432205 /// XR_432206 0007165 // signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208535_x_at NM_005203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005203.1 /DEF=Homo sapiens collagen, type XIII, alpha 1 (COL13A1), mRNA. /FEA=CDS /GEN=COL13A1 /PROD=collagen, type XIII, alpha 1 /DB_XREF=gi:4885144 /UG=Hs.211933 collagen, type XIII, alpha 1 /FL=gb:NM_005203.1 NM_005203 collagen, type XIII, alpha 1 COL13A1 1305 NM_001130103 /// NM_005203 /// NM_080798 /// NM_080799 /// NM_080800 /// NM_080801 /// NM_080802 /// NM_080803 /// NM_080804 /// NM_080805 /// NM_080806 /// NM_080807 /// NM_080808 /// NM_080809 /// NM_080810 /// NM_080811 /// NM_080812 /// NM_080813 /// NM_080814 /// NM_080815 /// XM_006717632 0001503 // ossification // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from physical interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from expression pattern /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005600 // collagen type XIII trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay 208536_s_at NM_006538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006538.1 /DEF=Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), mRNA. /FEA=CDS /GEN=BCL2L11 /PROD=BCL2-like 11 (apoptosis facilitator) /DB_XREF=gi:5729739 /UG=Hs.202657 BCL2-like 11 (apoptosis facilitator) /FL=gb:AF032458.1 gb:NM_006538.1 NM_006538 BCL2-like 11 (apoptosis facilitator) BCL2L11 10018 NM_001204106 /// NM_001204107 /// NM_001204108 /// NM_001204109 /// NM_001204110 /// NM_001204111 /// NM_001204112 /// NM_001204113 /// NM_006538 /// NM_138621 /// NM_138622 /// NM_138623 /// NM_138624 /// NM_138625 /// NM_138626 /// NM_138627 /// NM_207002 /// NM_207003 /// XM_005263550 /// XM_005263551 /// XM_005263552 /// XM_005263553 /// XM_005263554 /// XM_005263555 /// XM_005263556 /// XM_005263557 /// XM_005263559 /// XM_005263560 /// XM_005263561 /// XR_244801 /// XR_244802 /// XR_244803 /// XR_244804 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0035148 // tube formation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043583 // ear development // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046620 // regulation of organ growth // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0060139 // positive regulation of apoptotic process by virus // inferred from electronic annotation /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902263 // apoptotic process involved in embryonic digit morphogenesis // inferred from electronic annotation /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0097140 // BIM-BCL-xl complex // inferred from direct assay /// 0097141 // BIM-BCL-2 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208537_at NM_004230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004230.1 /DEF=Homo sapiens endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 (EDG5), mRNA. /FEA=CDS /GEN=EDG5 /PROD=endothelial differentiation, sphingolipidG-protein-coupled receptor, 5 /DB_XREF=gi:4758239 /UG=Hs.202672 endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 /FL=gb:AF034780.1 gb:NM_004230.1 NM_004230 sphingosine-1-phosphate receptor 2 S1PR2 9294 NM_004230 /// XM_006722936 0000187 // activation of MAPK activity // traceable author statement /// 0003376 // sphingosine-1-phosphate signaling pathway // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0038036 // sphingosine-1-phosphate receptor activity // inferred from electronic annotation 208538_at NM_012403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012403.1 /DEF=Homo sapiens pp32 related 1 (PP32R1), mRNA. /FEA=CDS /GEN=PP32R1 /PROD=pp32 related 1 /DB_XREF=gi:6912603 /UG=Hs.241573 pp32 related 1 /FL=gb:NM_012403.1 NM_012403 acidic (leucine-rich) nuclear phosphoprotein 32 family, member C ANP32C 23520 NM_012403 208539_x_at NM_006945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006945.1 /DEF=Homo sapiens small proline-rich protein 2B (SPRR2B), mRNA. /FEA=CDS /GEN=SPRR2B /PROD=small proline-rich protein 2B /DB_XREF=gi:5902119 /UG=Hs.231622 small proline-rich protein 2B /FL=gb:NM_006945.1 NM_006945 small proline-rich protein 2B SPRR2B 6701 NM_001017418 0008544 // epidermis development // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208540_x_at NM_021039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021039.1 /DEF=Homo sapiens S100 calcium-binding protein A14 (calgizzarin) (S100A14), mRNA. /FEA=CDS /GEN=S100A14 /PROD=S100 calcium-binding protein A14 (calgizzarin) /DB_XREF=gi:10567825 /UG=Hs.247697 S100 calcium-binding protein A14 (calgizzarin) /FL=gb:NM_021039.1 NM_021039 S100 calcium binding protein A11 pseudogene 1 /// S100A11P1 /// S100A11P1 208541_x_at NM_012251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012251.1 /DEF=Homo sapiens transcription factor A, mitochondrial (TFAM), mRNA. /FEA=CDS /GEN=TFAM /PROD=transcription factor A, mitochondrial /DB_XREF=gi:6912699 /UG=Hs.239379 transcription factor A, mitochondrial /FL=gb:NM_012251.1 NM_012251 transcription factor A, mitochondrial TFAM 7019 NM_001270782 /// NM_003201 /// NM_012251 /// NR_073073 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033108 // mitochondrial respiratory chain complex assembly // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay 208542_x_at NM_007153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007153.1 /DEF=Homo sapiens zinc finger protein 208 (ZNF208), mRNA. /FEA=CDS /GEN=ZNF208 /PROD=zinc finger protein 208 /DB_XREF=gi:6005975 /UG=Hs.233550 zinc finger protein 208 /FL=gb:NM_007153.1 NM_007153 zinc finger protein 208 /// zinc finger protein 595 /// zinc finger protein 718 ZNF208 /// ZNF595 /// ZNF718 7757 /// 152687 /// 255403 NM_001039127 /// NM_001286052 /// NM_001286053 /// NM_001286054 /// NM_001289930 /// NM_001289931 /// NM_007153 /// NM_182524 /// NR_110527 /// NR_110528 /// NR_110529 /// XM_005278364 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208543_at NM_013939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013939.1 /DEF=Homo sapiens olfactory receptor, family 10, subfamily H, member 2 (OR10H2), mRNA. /FEA=CDS /GEN=OR10H2 /PROD=olfactory receptor, family 10, subfamily H,member 2 /DB_XREF=gi:7330336 /UG=Hs.247694 olfactory receptor, family 10, subfamily H, member 2 /FL=gb:NM_013939.1 NM_013939 olfactory receptor, family 10, subfamily H, member 2 OR10H2 26538 NM_013939 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 208544_at NM_000682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000682.1 /DEF=Homo sapiens adrenergic, alpha-2B-, receptor (ADRA2B), mRNA. /FEA=CDS /GEN=ADRA2B /PROD=adrenergic, alpha-2B-, receptor /DB_XREF=gi:4501964 /UG=Hs.247686 adrenergic, alpha-2B-, receptor /FL=gb:NM_000682.1 NM_000682 adrenoceptor alpha 2B ADRA2B 151 NM_000682 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0003056 // regulation of vascular smooth muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // non-traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032811 // negative regulation of epinephrine secretion // non-traceable author statement /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071883 // activation of MAPK activity by adrenergic receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004938 // alpha2-adrenergic receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0051379 // epinephrine binding // inferred from direct assay 208545_x_at NM_003185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003185.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD (TAF2C1), mRNA. /FEA=CDS /GEN=TAF2C1 /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, C1, 130kD /DB_XREF=gi:4507348 /UG=Hs.24644 TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD /FL=gb:NM_003185.1 NM_003185 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa TAF4 6874 NM_003185 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208546_x_at NM_003524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003524.1 /DEF=Homo sapiens H2B histone family, member J (H2BFJ), mRNA. /FEA=CDS /GEN=H2BFJ /PROD=H2B histone family, member J /DB_XREF=gi:4504268 /UG=Hs.249216 H2B histone family, member J /FL=gb:NM_003524.1 NM_003524 histone cluster 1, H2bh HIST1H2BH 8345 NM_003524 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208547_at NM_021062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021062.1 /DEF=Homo sapiens H2B histone family, member F (H2BFF), mRNA. /FEA=CDS /GEN=H2BFF /PROD=H2B histone family, member F /DB_XREF=gi:10800139 /UG=Hs.248134 H2B histone family, member F /FL=gb:NM_021062.1 NM_021062 histone cluster 1, H2bb HIST1H2BB 3018 NM_021062 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208548_at NM_021002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021002.1 /DEF=Homo sapiens interferon, alpha 6 (IFNA6), mRNA. /FEA=CDS /GEN=IFNA6 /PROD=interferon, alpha 6 /DB_XREF=gi:11128014 /UG=Hs.247933 interferon, alpha 6 /FL=gb:NM_021002.1 NM_021002 interferon, alpha 5 /// interferon, alpha 6 IFNA5 /// IFNA6 3442 /// 3443 NM_002169 /// NM_021002 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 208549_x_at NM_016171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016171.1 /DEF=Homo sapiens prothymosin a14 (LOC51685), mRNA. /FEA=CDS /GEN=LOC51685 /PROD=prothymosin a14 /DB_XREF=gi:7706414 /UG=Hs.247919 prothymosin a14 /FL=gb:AF170294.1 gb:NM_016171.1 NM_016171 prothymosin, alpha PTMA 5757 NM_001099285 /// NM_002823 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 208550_x_at NM_012283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012283.1 /DEF=Homo sapiens potassium voltage-gated channel, subfamily G, member 2 (KCNG2), mRNA. /FEA=CDS /GEN=KCNG2 /PROD=potassium voltage-gated channel, subfamily G,member 2 /DB_XREF=gi:6912443 /UG=Hs.247905 potassium voltage-gated channel, subfamily G, member 2 /FL=gb:NM_012283.1 NM_012283 potassium voltage-gated channel, subfamily G, member 2 KCNG2 26251 NM_012283 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208551_at NM_003547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003547.1 /DEF=Homo sapiens H4 histone family, member L (H4FL), mRNA. /FEA=CDS /GEN=H4FL /PROD=H4 histone family, member L /DB_XREF=gi:4504318 /UG=Hs.247815 H4 histone family, member L /FL=gb:NM_003547.1 NM_003547 histone cluster 1, H4g HIST1H4G 8369 NM_003547 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208552_at NM_014619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014619.1 /DEF=Homo sapiens glutamate receptor, ionotropic, kainate 4 (GRIK4), mRNA. /FEA=CDS /GEN=GRIK4 /PROD=glutamate receptor, ionotropic, kainate 4 /DB_XREF=gi:7657143 /UG=Hs.248034 glutamate receptor, ionotropic, kainate 4 /FL=gb:NM_014619.1 NM_014619 glutamate receptor, ionotropic, kainate 4 GRIK4 2900 NM_001282470 /// NM_001282473 /// NM_014619 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // not recorded 208553_at NM_005321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005321.1 /DEF=Homo sapiens H1 histone family, member 4 (H1F4), mRNA. /FEA=CDS /GEN=H1F4 /PROD=H1 histone family, member 4 /DB_XREF=gi:4885378 /UG=Hs.248133 H1 histone family, member 4 /FL=gb:NM_005321.1 NM_005321 histone cluster 1, H1e HIST1H1E 3008 NM_005321 0006334 // nucleosome assembly // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 208554_at NM_002700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002700.1 /DEF=Homo sapiens POU domain, class 4, transcription factor 3 (POU4F3), mRNA. /FEA=CDS /GEN=POU4F3 /PROD=POU domain, class 4, transcription factor 3 /DB_XREF=gi:4505964 /UG=Hs.248019 POU domain, class 4, transcription factor 3 /FL=gb:NM_002700.1 NM_002700 POU class 4 homeobox 3 POU4F3 5459 NM_002700 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0021562 // vestibulocochlear nerve development // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048675 // axon extension // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208555_x_at NM_001322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001322.1 /DEF=Homo sapiens cystatin SA (CST2), mRNA. /FEA=CDS /GEN=CST2 /PROD=cystatin SA /DB_XREF=gi:4503104 /UG=Hs.247955 cystatin SA /FL=gb:NM_001322.1 NM_001322 cystatin SA CST2 1470 NM_001322 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 208556_at NM_005299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005299.1 /DEF=Homo sapiens G protein-coupled receptor 31 (GPR31), mRNA. /FEA=CDS /GEN=GPR31 /PROD=G protein-coupled receptor 31 /DB_XREF=gi:4885316 /UG=Hs.248124 G protein-coupled receptor 31 /FL=gb:NM_005299.1 NM_005299 G protein-coupled receptor 31 GPR31 2853 NM_005299 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 208557_at NM_024014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024014.1 /DEF=Homo sapiens homeo box A6 (HOXA6), mRNA. /FEA=CDS /GEN=HOXA6 /PROD=homeo box A6 /DB_XREF=gi:13489076 /UG=Hs.248073 homeo box A6 /FL=gb:NM_024014.1 NM_024014 homeobox A6 HOXA6 3203 NM_024014 /// XM_006715716 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208558_at NM_013940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013940.1 /DEF=Homo sapiens olfactory receptor, family 10, subfamily H, member 1 (OR10H1), mRNA. /FEA=CDS /GEN=OR10H1 /PROD=olfactory receptor, family 10, subfamily H,member 1 /DB_XREF=gi:7363438 /UG=Hs.248088 olfactory receptor, family 10, subfamily H, member 1 /FL=gb:NM_013940.1 NM_013940 olfactory receptor, family 10, subfamily H, member 1 OR10H1 26539 NM_013940 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 208559_at NM_013311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013311.1 /DEF=Homo sapiens insulin upstream factor 1 (IUF1), mRNA. /FEA=CDS /GEN=IUF1 /PROD=insulin upstream factor 1 /DB_XREF=gi:7019436 /UG=Hs.248085 insulin upstream factor 1 /FL=gb:AF049893.1 gb:NM_013311.1 NM_013311 pancreatic and duodenal homeobox 1 PDX1 3651 NM_000209 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003309 // type B pancreatic cell differentiation // inferred from direct assay /// 0003309 // type B pancreatic cell differentiation // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010040 // response to iron(II) ion // inferred from electronic annotation /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010260 // organ senescence // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033273 // response to vitamin // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051594 // detection of glucose // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208560_at NM_005549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005549.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 10 (KCNA10), mRNA. /FEA=CDS /GEN=KCNA10 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 10 /DB_XREF=gi:5031818 /UG=Hs.248140 potassium voltage-gated channel, shaker-related subfamily, member 10 /FL=gb:NM_005549.1 NM_005549 potassium voltage-gated channel, shaker-related subfamily, member 10 KCNA10 3744 NM_005549 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005221 // intracellular cyclic nucleotide activated cation channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208561_at NM_020297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020297.1 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 9 (ABCC9), transcript variant SUR2B, mRNA. /FEA=CDS /GEN=ABCC9 /PROD=ATP-binding cassette, sub-family C, member 9,isoform SUR2B /DB_XREF=gi:10947121 /UG=Hs.248960 ATP-binding cassette, sub-family C (CFTRMRP), member 9 /FL=gb:NM_020297.1 NM_020297 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 ABCC9 10060 NM_005691 /// NM_020297 /// NM_020298 /// XM_005253284 /// XM_005253286 /// XM_005253287 /// XM_005253288 /// XM_005253289 /// XM_005253290 /// XM_005253291 /// XM_006719025 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0008282 // ATP-sensitive potassium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008281 // sulfonylurea receptor activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 208562_s_at NM_020297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020297.1 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 9 (ABCC9), transcript variant SUR2B, mRNA. /FEA=CDS /GEN=ABCC9 /PROD=ATP-binding cassette, sub-family C, member 9,isoform SUR2B /DB_XREF=gi:10947121 /UG=Hs.248960 ATP-binding cassette, sub-family C (CFTRMRP), member 9 /FL=gb:NM_020297.1 NM_020297 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 ABCC9 10060 NM_005691 /// NM_020297 /// NM_020298 /// XM_005253284 /// XM_005253286 /// XM_005253287 /// XM_005253288 /// XM_005253289 /// XM_005253290 /// XM_005253291 /// XM_006719025 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0008282 // ATP-sensitive potassium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008281 // sulfonylurea receptor activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 208563_x_at NM_006236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006236.1 /DEF=Homo sapiens POU domain, class 3, transcription factor 3 (POU3F3), mRNA. /FEA=CDS /GEN=POU3F3 /PROD=POU domain, class 3, transcription factor 3 /DB_XREF=gi:5453935 /UG=Hs.248158 POU domain, class 3, transcription factor 3 /FL=gb:NM_006236.1 NM_006236 POU class 3 homeobox 3 POU3F3 5455 NM_006236 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021869 // forebrain ventricular zone progenitor cell division // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0072218 // metanephric ascending thin limb development // inferred from sequence or structural similarity /// 0072227 // metanephric macula densa development // inferred from sequence or structural similarity /// 0072233 // metanephric thick ascending limb development // inferred from sequence or structural similarity /// 0072236 // metanephric loop of Henle development // inferred from sequence or structural similarity /// 0072240 // metanephric DCT cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0071837 // HMG box domain binding // inferred from electronic annotation 208564_at NM_004974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004974.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 2 (KCNA2), mRNA. /FEA=CDS /GEN=KCNA2 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, member 2 /DB_XREF=gi:4826781 /UG=Hs.248139 potassium voltage-gated channel, shaker-related subfamily, member 2 /FL=gb:L02752.1 gb:NM_004974.1 NM_004974 potassium voltage-gated channel, shaker-related subfamily, member 2 KCNA2 3737 NM_001204269 /// NM_004974 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0021633 // optic nerve structural organization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation 208565_at NM_005913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005913.1 /DEF=Homo sapiens melanocortin 5 receptor (MC5R), mRNA. /FEA=CDS /GEN=MC5R /PROD=melanocortin 5 receptor /DB_XREF=gi:5174534 /UG=Hs.248145 melanocortin 5 receptor /FL=gb:NM_005913.1 NM_005913 melanocortin 5 receptor MC5R 4161 NM_005913 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042562 // hormone binding // inferred from electronic annotation 208566_at NM_002244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002244.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, inhibitor 1 (KCNJN1), mRNA. /FEA=CDS /GEN=KCNJN1 /PROD=potassium inwardly-rectifying channel, subfamilyJ, inhibitor 1 /DB_XREF=gi:4504844 /UG=Hs.248143 potassium inwardly-rectifying channel, subfamily J, inhibitor 1 /FL=gb:NM_002244.1 NM_002244 ATP-sensitive inward rectifier potassium channel 12-like LOC100996843 100996843 XM_003846726 208567_s_at NM_002244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002244.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, inhibitor 1 (KCNJN1), mRNA. /FEA=CDS /GEN=KCNJN1 /PROD=potassium inwardly-rectifying channel, subfamilyJ, inhibitor 1 /DB_XREF=gi:4504844 /UG=Hs.248143 potassium inwardly-rectifying channel, subfamily J, inhibitor 1 /FL=gb:NM_002244.1 NM_002244 potassium inwardly-rectifying channel, subfamily J, member 12 /// potassium inwardly-rectifying channel, subfamily J, member 18 /// ATP-sensitive inward rectifier potassium channel 12-like KCNJ12 /// KCNJ18 /// LOC100996843 3768 /// 100134444 /// 100996843 NM_001194958 /// NM_021012 /// XM_003846726 /// XM_005256625 /// XM_005276919 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0006936 // muscle contraction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 208568_at NM_000529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000529.1 /DEF=Homo sapiens melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), mRNA. /FEA=CDS /GEN=MC2R /PROD=melanocortin 2 receptor /DB_XREF=gi:4505126 /UG=Hs.248144 melanocortin 2 receptor (adrenocorticotropic hormone) /FL=gb:NM_000529.1 NM_000529 melanocortin 2 receptor (adrenocorticotropic hormone) MC2R 4158 NM_000529 /// NM_001291911 0001890 // placenta development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004978 // corticotropin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208569_at NM_003513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003513.1 /DEF=Homo sapiens H2A histone family, member M (H2AFM), mRNA. /FEA=CDS /GEN=H2AFM /PROD=H2A histone family, member M /DB_XREF=gi:4504246 /UG=Hs.248174 H2A histone family, member M /FL=gb:NM_003513.1 NM_003513 histone cluster 1, H2ab HIST1H2AB 8335 NM_003513 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208570_at NM_005430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005430.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 1 (WNT1), mRNA. /FEA=CDS /GEN=WNT1 /PROD=wingless-type MMTV integration site family,member 1 /DB_XREF=gi:4885654 /UG=Hs.248164 wingless-type MMTV integration site family, member 1 /FL=gb:NM_005430.1 NM_005430 wingless-type MMTV integration site family, member 1 WNT1 7471 NM_005430 0000578 // embryonic axis specification // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009611 // response to wounding // inferred from expression pattern /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021536 // diencephalon development // inferred from electronic annotation /// 0021551 // central nervous system morphogenesis // inferred from sequence or structural similarity /// 0021588 // cerebellum formation // inferred from sequence or structural similarity /// 0021797 // forebrain anterior/posterior pattern specification // inferred from electronic annotation /// 0022004 // midbrain-hindbrain boundary maturation during brain development // inferred from electronic annotation /// 0022037 // metencephalon development // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from mutant phenotype /// 0030182 // neuron differentiation // not recorded /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from electronic annotation /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030917 // midbrain-hindbrain boundary development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0060061 // Spemann organizer formation // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype /// 0061184 // positive regulation of dermatome development // inferred from direct assay /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005109 // frizzled binding // inferred by curator /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048018 // receptor agonist activity // inferred by curator 208571_at NM_012404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012404.1 /DEF=Homo sapiens pp32 related 2 (PP32R2), mRNA. /FEA=CDS /GEN=PP32R2 /PROD=pp32 related 2 /DB_XREF=gi:6912605 /UG=Hs.248221 pp32 related 2 /FL=gb:NM_012404.1 NM_012404 acidic (leucine-rich) nuclear phosphoprotein 32 family, member D ANP32D 23519 NM_012404 208572_at NM_003493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003493.1 /DEF=Homo sapiens H3 histone family, member T (H3FT), mRNA. /FEA=CDS /GEN=H3FT /PROD=H3 histone family, member T /DB_XREF=gi:4504298 /UG=Hs.248171 H3 histone family, member T /FL=gb:NM_003493.1 NM_003493 histone cluster 3, H3 HIST3H3 8290 NM_003493 0000723 // telomere maintenance // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208573_s_at NM_007160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007160.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily H, member 3 (OR2H3), mRNA. /FEA=CDS /GEN=OR2H3 /PROD=olfactory receptor, family 2, subfamily H,member 3 /DB_XREF=gi:6005821 /UG=Hs.248169 olfactory receptor, family 2, subfamily H, member 3 /FL=gb:NM_007160.1 NM_007160 olfactory receptor, family 2, subfamily H, member 2 OR2H2 7932 NM_007160 /// XM_005249407 /// XM_005272893 /// XM_005274892 /// XM_005275048 /// XM_005275183 /// XM_005275306 /// XM_005275478 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007618 // mating // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208574_at NM_004189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004189.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 14 (SOX14), mRNA. /FEA=CDS /GEN=SOX14 /PROD=SRY (sex determining region Y)-box 14 /DB_XREF=gi:4759161 /UG=Hs.248184 SRY (sex determining region Y)-box 14 /FL=gb:NM_004189.1 NM_004189 SRY (sex determining region Y)-box 14 SOX14 8403 NM_004189 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 208575_at NM_003529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003529.1 /DEF=Homo sapiens H3 histone family, member A (H3FA), mRNA. /FEA=CDS /GEN=H3FA /PROD=H3 histone family, member A /DB_XREF=gi:4504280 /UG=Hs.248175 H3 histone family, member A /FL=gb:NM_003529.1 NM_003529 histone cluster 1, H3a HIST1H3A 8350 NM_003529 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208576_s_at NM_003537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003537.1 /DEF=Homo sapiens H3 histone family, member L (H3FL), mRNA. /FEA=CDS /GEN=H3FL /PROD=H3 histone family, member L /DB_XREF=gi:4504296 /UG=Hs.248177 H3 histone family, member L /FL=gb:NM_003537.1 NM_003537 histone cluster 1, H3b HIST1H3B 8358 NM_003537 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208577_at NM_003531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003531.1 /DEF=Homo sapiens H3 histone family, member C (H3FC), mRNA. /FEA=CDS /GEN=H3FC /PROD=H3 histone family, member C /DB_XREF=gi:4504284 /UG=Hs.248176 H3 histone family, member C /FL=gb:NM_003531.1 NM_003531 histone cluster 1, H3c HIST1H3C 8352 NM_003531 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208578_at NM_006514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006514.1 /DEF=Homo sapiens sodium channel, voltage-gated, type X, alpha polypeptide (SCN10A), mRNA. /FEA=CDS /GEN=SCN10A /PROD=sodium channel, voltage-gated, type X, alphapolypeptide /DB_XREF=gi:5730032 /UG=Hs.250443 sodium channel, voltage-gated, type X, alpha polypeptide /FL=gb:AF117907.1 gb:NM_006514.1 NM_006514 sodium channel, voltage-gated, type X, alpha subunit SCN10A 6336 NM_001293306 /// NM_001293307 /// NM_006514 /// XM_005265371 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007600 // sensory perception // traceable author statement /// 0019228 // neuronal action potential // not recorded /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded /// 0086067 // AV node cell to bundle of His cell communication // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0044299 // C-fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071439 // clathrin complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005272 // sodium channel activity // inferred from electronic annotation 208579_x_at NM_017445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017445.1 /DEF=Homo sapiens H2B histone family, member S (H2BFS), mRNA. /FEA=CDS /GEN=H2BFS /PROD=H2B histone family, member S /DB_XREF=gi:11036645 /UG=Hs.306200 H2B histone family, member S /FL=gb:NM_017445.1 NM_017445 H2B histone family, member S (pseudogene) H2BFS 54145 NM_017445 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208580_x_at NM_021968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021968.1 /DEF=Homo sapiens H4 histone family, member E (H4FE), mRNA. /FEA=CDS /GEN=H4FE /PROD=H4 histone family, member E /DB_XREF=gi:11415029 /UG=Hs.278483 H4 histone family, member E /FL=gb:NM_021968.1 NM_021968 histone cluster 1, H4a /// histone cluster 1, H4b /// histone cluster 1, H4c /// histone cluster 1, H4d /// histone cluster 1, H4e /// histone cluster 1, H4f /// histone cluster 1, H4h /// histone cluster 1, H4i /// histone cluster 1, H4j /// histone cluster 1, H4k /// histone cluster 1, H4l /// histone cluster 2, H4a /// histone cluster 2, H4b /// histone cluster 4, H4 HIST1H4A /// HIST1H4B /// HIST1H4C /// HIST1H4D /// HIST1H4E /// HIST1H4F /// HIST1H4H /// HIST1H4I /// HIST1H4J /// HIST1H4K /// HIST1H4L /// HIST2H4A /// HIST2H4B /// HIST4H4 8294 /// 8359 /// 8360 /// 8361 /// 8362 /// 8363 /// 8364 /// 8365 /// 8366 /// 8367 /// 8368 /// 8370 /// 121504 /// 554313 NM_001034077 /// NM_003495 /// NM_003538 /// NM_003539 /// NM_003540 /// NM_003541 /// NM_003542 /// NM_003543 /// NM_003544 /// NM_003545 /// NM_003546 /// NM_003548 /// NM_021968 /// NM_175054 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208581_x_at NM_005952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005952.1 /DEF=Homo sapiens metallothionein 1X (MT1X), mRNA. /FEA=CDS /GEN=MT1X /PROD=metallothionein 1X /DB_XREF=gi:10835231 /UG=Hs.278462 metallothionein 1X /FL=gb:NM_005952.1 NM_005952 metallothionein 1X MT1X 4501 NM_005952 0010038 // response to metal ion // traceable author statement /// 0036018 // cellular response to erythropoietin // inferred from expression pattern /// 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // traceable author statement 208582_s_at NM_012148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012148.1 /DEF=Homo sapiens double homeobox, 3 (DUX3), mRNA. /FEA=CDS /GEN=DUX3 /PROD=double homeobox, 3 /DB_XREF=gi:6912343 /UG=Hs.258591 double homeobox, 3 /FL=gb:NM_012148.1 NM_012148 double homeobox 1 /// double homeobox 3 /// double homeobox 5 DUX1 /// DUX3 /// DUX5 26581 /// 26582 /// 26584 NM_012146 /// NM_012148 /// NM_012149 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208583_x_at NM_021066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021066.1 /DEF=Homo sapiens H2A histone family, member E (H2AFE), mRNA. /FEA=CDS /GEN=H2AFE /PROD=H2A histone family, member E /DB_XREF=gi:10800143 /UG=Hs.274590 H2A histone family, member E /FL=gb:NM_021066.1 NM_021066 histone cluster 1, H2aj HIST1H2AJ 8331 NM_021066 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208584_at NM_016432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016432.1 /DEF=Homo sapiens synoretin (LOC51749), mRNA. /FEA=CDS /GEN=LOC51749 /PROD=synoretin /DB_XREF=gi:7706538 /UG=Hs.279002 synoretin /FL=gb:AF219258.1 gb:NM_016432.1 NM_016432 synuclein, gamma (breast cancer-specific protein 1) SNCG 6623 NM_003087 /// XM_005270065 /// XM_005270066 /// XM_005270067 0002118 // aggressive behavior // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0071464 // cellular response to hydrostatic pressure // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 208585_at NM_024018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024018.1 /DEF=Homo sapiens butyrophilin, subfamily 2, member A3 (BTN2A3), mRNA. /FEA=CDS /GEN=BTN2A3 /PROD=butyrophilin, subfamily 2, member A3 /DB_XREF=gi:13184051 /UG=Hs.302077 butyrophilin, subfamily 2, member A3 /FL=gb:NM_024018.1 NM_024018 butyrophilin, subfamily 2, member A3, pseudogene BTN2A3P 54718 NM_024018 /// NR_027795 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 208586_s_at NM_005636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005636.1 /DEF=Homo sapiens synovial sarcoma, X breakpoint 4 (SSX4), mRNA. /FEA=CDS /GEN=SSX4 /PROD=synovial sarcoma, X breakpoint 4 /DB_XREF=gi:5032122 /UG=Hs.278632 synovial sarcoma, X breakpoint 4 /FL=gb:U90841.1 gb:NM_005636.1 NM_005636 synovial sarcoma, X breakpoint 4 /// synovial sarcoma, X breakpoint 4B SSX4 /// SSX4B 6759 /// 548313 NM_001034832 /// NM_001040612 /// NM_005636 /// NM_175729 /// XM_006726844 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 208587_s_at NM_003554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003554.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily E, member 2 (OR1E2), mRNA. /FEA=CDS /GEN=OR1E2 /PROD=olfactory receptor, family 1, subfamily E,member 2 /DB_XREF=gi:11386152 /UG=Hs.278486 olfactory receptor, family 1, subfamily E, member 2 /FL=gb:NM_003554.1 NM_003554 olfactory receptor, family 1, subfamily E, member 1 /// olfactory receptor, family 1, subfamily E, member 2 OR1E1 /// OR1E2 8387 /// 8388 NM_003553 /// NM_003554 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement /// 0004984 // olfactory receptor activity // inferred from electronic annotation 208588_at NM_021631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021631.1 /DEF=Homo sapiens apoptosis inhibitor (FKSG2), mRNA. /FEA=CDS /GEN=FKSG2 /PROD=apoptosis inhibitor /DB_XREF=gi:11056001 /UG=Hs.302015 apoptosis inhibitor /FL=gb:AF300871.1 gb:NM_021631.1 NM_021631 tumor protein, translationally-controlled 1 pseudogene 8 TPT1P8 59347 NM_021631 0006915 // apoptotic process // inferred from electronic annotation 208589_at NM_020389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020389.1 /DEF=Homo sapiens putative capacitative calcium channel (trp7), mRNA. /FEA=CDS /GEN=trp7 /PROD=putative capacitative calcium channel /DB_XREF=gi:9966864 /UG=Hs.283104 putative capacitative calcium channel /FL=gb:NM_020389.1 NM_020389 transient receptor potential cation channel, subfamily C, member 7 TRPC7 57113 NM_001167576 /// NM_001167577 /// NM_020389 /// XM_005272036 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208590_x_at NM_021954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021954.1 /DEF=Homo sapiens gap junction protein, alpha 3, 46kD (connexin 46) (GJA3), mRNA. /FEA=CDS /GEN=GJA3 /PROD=gap junction protein, alpha 3, 46kD (connexin46) /DB_XREF=gi:13489109 /UG=Hs.283746 gap junction protein, alpha 3, 46kD (connexin 46) /FL=gb:NM_021954.1 NM_021954 gap junction protein, alpha 3, 46kDa GJA3 2700 NM_021954 /// XM_005266353 0006810 // transport // non-traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // inferred from electronic annotation 208591_s_at NM_000922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000922.1 /DEF=Homo sapiens phosphodiesterase 3B, cGMP-inhibited (PDE3B), mRNA. /FEA=CDS /GEN=PDE3B /PROD=phosphodiesterase 3B, cGMP-inhibited /DB_XREF=gi:4505660 /UG=Hs.326528 phosphodiesterase 3B, cGMP-inhibited /FL=gb:NM_000922.1 NM_000922 phosphodiesterase 3B, cGMP-inhibited PDE3B 5140 NM_000922 /// XM_005252972 /// XM_006718249 0001525 // angiogenesis // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from expression pattern /// 0007162 // negative regulation of cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred by curator /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred by curator /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004119 // cGMP-inhibited cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 208592_s_at NM_030893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030893.1 /DEF=Homo sapiens CD1E antigen, e polypeptide (CD1E), mRNA. /FEA=CDS /GEN=CD1E /PROD=CD1E antigen, e polypeptide /DB_XREF=gi:13569859 /FL=gb:NM_030893.1 NM_030893 CD1e molecule CD1E 913 NM_001042583 /// NM_001042584 /// NM_001042585 /// NM_001042586 /// NM_001042587 /// NM_001185107 /// NM_001185108 /// NM_001185110 /// NM_001185112 /// NM_001185113 /// NM_001185114 /// NM_001185115 /// NM_030893 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030883 // endogenous lipid antigen binding // not recorded /// 0030884 // exogenous lipid antigen binding // not recorded /// 0071723 // lipopeptide binding // not recorded 208593_x_at NM_004382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004382.1 /DEF=Homo sapiens corticotropin releasing hormone receptor 1 (CRHR1), mRNA. /FEA=CDS /GEN=CRHR1 /PROD=corticotropin releasing hormone receptor 1 /DB_XREF=gi:4758059 /UG=Hs.79117 corticotropin releasing hormone receptor 1 /FL=gb:NM_004382.1 gb:U16273.1 NM_004382 corticotropin releasing hormone receptor 1 CRHR1 1394 NM_001145146 /// NM_001145147 /// NM_001145148 /// NM_001256299 /// NM_004382 0001666 // response to hypoxia // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007567 // parturition // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010578 // regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0051458 // corticotropin secretion // inferred from sequence or structural similarity /// 0051867 // general adaptation syndrome, behavioral process // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0071376 // cellular response to corticotropin-releasing hormone stimulus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000852 // regulation of corticosterone secretion // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015056 // corticotrophin-releasing factor receptor activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043404 // corticotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0051424 // corticotropin-releasing hormone binding // inferred from electronic annotation 208594_x_at NM_024318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024318.1 /DEF=Homo sapiens immunoglobulin-like transcript 8 (ILT8), mRNA. /FEA=CDS /GEN=ILT8 /PROD=immunoglobulin-like transcript 8 /DB_XREF=gi:13324689 /UG=Hs.306230 immunoglobulin-like transcript 8 /FL=gb:NM_024318.1 gb:AF041262.1 NM_024318 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 LILRA6 79168 NM_024318 /// NR_104098 /// XM_006723379 /// XM_006723380 /// XM_006726275 /// XM_006726310 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 208595_s_at NM_015845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015845.1 /DEF=Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 2, mRNA. /FEA=CDS /GEN=MBD1 /PROD=methyl-CpG binding domain protein 1, isoform 2 /DB_XREF=gi:7710136 /UG=Hs.6211 methyl-CpG binding domain protein 1 /FL=gb:AF078831.1 gb:NM_015845.1 NM_015845 methyl-CpG binding domain protein 1 MBD1 4152 NM_001204136 /// NM_001204137 /// NM_001204138 /// NM_001204139 /// NM_001204140 /// NM_001204141 /// NM_001204142 /// NM_001204143 /// NM_001204151 /// NM_002384 /// NM_015844 /// NM_015845 /// NM_015846 /// NM_015847 /// XM_005258262 /// XM_005258264 /// XM_005258265 /// XM_005258268 /// XM_005258271 /// XM_005258272 /// XM_005258274 /// XM_006722452 /// XM_006722453 /// XM_006722454 /// XM_006722455 /// XM_006722456 /// XM_006722457 /// XM_006722458 /// XM_006722459 /// XM_006722460 /// XM_006722461 /// XM_006722462 /// XM_006722463 /// XM_006722464 /// XM_006722465 /// XM_006722466 /// XM_006722467 /// XM_006722468 /// XM_006722469 /// XM_006722470 /// XM_006722471 /// XM_006722472 /// XM_006722473 /// XM_006722474 /// XM_006722475 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 208596_s_at NM_019093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019093.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A3 (UGT1A3), mRNA. /FEA=CDS /GEN=UGT1A3 /PROD=UDP glycosyltransferase 1 family, polypeptideA3 /DB_XREF=gi:13487899 /UG=Hs.326543 UDP glycosyltransferase 1 family, polypeptide A3 /FL=gb:NM_019093.1 NM_019093 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A10 /// UDP glucuronosyltransferase 1 family, polypeptide A3 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A5 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A7 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A10 /// UGT1A3 /// UGT1A4 /// UGT1A5 /// UGT1A6 /// UGT1A7 /// UGT1A8 /// UGT1A9 54575 /// 54576 /// 54577 /// 54578 /// 54579 /// 54600 /// 54657 /// 54658 /// 54659 NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_019077 /// NM_019078 /// NM_019093 /// NM_021027 /// NM_205862 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0051552 // flavone metabolic process // inferred by curator /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0001972 // retinoic acid binding // inferred by curator /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008144 // drug binding // inferred from direct assay /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred by curator /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 208597_at NM_000614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000614.1 /DEF=Homo sapiens ciliary neurotrophic factor (CNTF), mRNA. /FEA=CDS /GEN=CNTF /PROD=ciliary neurotrophic factor /DB_XREF=gi:4758019 /UG=Hs.46366 ciliary neurotrophic factor /FL=gb:NM_000614.1 NM_000614 ciliary neurotrophic factor CNTF 1270 NM_000614 0007165 // signal transduction // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from electronic annotation /// 0046668 // regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0005615 // extracellular space // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0097058 // CRLF-CLCF1 complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // traceable author statement /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208598_s_at NM_005703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005703.2 /DEF=Homo sapiens upstream regulatory element binding protein 1 (UREB1), mRNA. /FEA=CDS /GEN=UREB1 /PROD=upstream regulatory element binding protein 1 /DB_XREF=gi:6692990 /UG=Hs.3383 upstream regulatory element binding protein 1 /FL=gb:NM_005703.2 NM_005703 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase HUWE1 10075 NM_031407 /// XM_005261965 /// XM_005261966 /// XM_005261967 /// XM_005261968 /// XM_005261969 /// XM_005261971 /// XM_005261972 /// XM_006724574 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208599_at NM_005703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005703.2 /DEF=Homo sapiens upstream regulatory element binding protein 1 (UREB1), mRNA. /FEA=CDS /GEN=UREB1 /PROD=upstream regulatory element binding protein 1 /DB_XREF=gi:6692990 /UG=Hs.3383 upstream regulatory element binding protein 1 /FL=gb:NM_005703.2 NM_005703 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase HUWE1 10075 NM_031407 /// XM_005261965 /// XM_005261966 /// XM_005261967 /// XM_005261968 /// XM_005261969 /// XM_005261971 /// XM_005261972 /// XM_006724574 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208600_s_at NM_001508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001508.1 /DEF=Homo sapiens G protein-coupled receptor 39 (GPR39), mRNA. /FEA=CDS /GEN=GPR39 /PROD=G protein-coupled receptor 39 /DB_XREF=gi:4504096 /UG=Hs.85339 G protein-coupled receptor 39 /FL=gb:AF034633.1 gb:NM_001508.1 NM_001508 G protein-coupled receptor 39 GPR39 2863 NM_001508 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208601_s_at NM_030773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030773.1 /DEF=Homo sapiens beta tubulin 1, class VI (TUBB1), mRNA. /FEA=CDS /GEN=TUBB1 /PROD=beta tubulin 1, class VI /DB_XREF=gi:13562113 /FL=gb:NM_030773.1 NM_030773 tubulin, beta 1 class VI TUBB1 81027 NM_030773 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 208602_x_at NM_006725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006725.1 /DEF=Homo sapiens CD6 antigen (CD6), mRNA. /FEA=CDS /GEN=CD6 /PROD=CD6 antigen /DB_XREF=gi:5802993 /UG=Hs.81226 CD6 antigen /FL=gb:U66142.1 gb:NM_006725.1 NM_006725 CD6 molecule CD6 923 NM_001254750 /// NM_001254751 /// NM_006725 /// NR_045638 /// XM_006718738 /// XM_006718739 /// XM_006718740 /// XM_006718741 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208603_s_at NM_016431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016431.1 /DEF=Homo sapiens mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), mRNA. /FEA=CDS /GEN=MAPK8IP2 /PROD=islet-brain 2 /DB_XREF=gi:7706536 /UG=Hs.80545 mitogen-activated protein kinase 8 interacting protein 2 /FL=gb:AF218778.1 gb:NM_016431.1 NM_016431 mitogen-activated protein kinase 8 interacting protein 2 MAPK8IP2 23542 NM_012324 /// NM_016431 /// NM_139124 0000165 // MAPK cascade // inferred from direct assay /// 0001662 // behavioral fear response // inferred from sequence or structural similarity /// 0007172 // signal complex assembly // traceable author statement /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007617 // mating behavior // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046958 // nonassociative learning // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // non-traceable author statement /// 0005078 // MAP-kinase scaffold activity // non-traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0032403 // protein complex binding // inferred from electronic annotation 208604_s_at NM_030661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030661.1 /DEF=Homo sapiens homeo box A3 (HOXA3), mRNA. /FEA=CDS /GEN=HOXA3 /PROD=homeo box A3 /DB_XREF=gi:13562111 /FL=gb:NM_030661.1 NM_030661 homeobox A3 HOXA3 3200 NM_030661 /// NM_153631 /// NM_153632 /// XM_005249730 /// XM_005249731 /// XM_005249732 /// XM_006715715 0001525 // angiogenesis // inferred from expression pattern /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010159 // specification of organ position // inferred from electronic annotation /// 0021615 // glossopharyngeal nerve morphogenesis // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060017 // parathyroid gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 208605_s_at NM_002529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002529.2 /DEF=Homo sapiens neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), mRNA. /FEA=CDS /GEN=NTRK1 /PROD=neurotrophic tyrosine kinase, receptor, type 1 /DB_XREF=gi:4585711 /UG=Hs.85844 neurotrophic tyrosine kinase, receptor, type 1 /FL=gb:NM_002529.2 NM_002529 neurotrophic tyrosine kinase, receptor, type 1 NTRK1 4914 NM_001007792 /// NM_001012331 /// NM_002529 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006606 // protein import into nucleus // traceable author statement /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008645 // hexose transport // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0010623 // developmental programmed cell death // inferred from sequence or structural similarity /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0021553 // olfactory nerve development // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0038180 // nerve growth factor signaling pathway // inferred from electronic annotation /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051599 // response to hydrostatic pressure // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060385 // axonogenesis involved in innervation // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0071316 // cellular response to nicotine // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0034399 // nuclear periphery // inferred from direct assay /// 0034399 // nuclear periphery // inferred from electronic annotation /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005030 // neurotrophin receptor activity // inferred from electronic annotation /// 0005166 // neurotrophin p75 receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0010465 // nerve growth factor receptor activity // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042289 // MHC class II protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043121 // neurotrophin binding // traceable author statement /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 208606_s_at NM_030761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030761.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 4 (WNT4), mRNA. /FEA=CDS /GEN=WNT4 /PROD=wingless-type MMTV integration site family,member 4 /DB_XREF=gi:13540518 /FL=gb:NM_030761.1 NM_030761 wingless-type MMTV integration site family, member 4 WNT4 54361 NM_030761 /// XM_005245897 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from expression pattern /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0001889 // liver development // inferred from expression pattern /// 0006702 // androgen biosynthetic process // inferred from direct assay /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0008585 // female gonad development // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030237 // female sex determination // inferred from mutant phenotype /// 0030325 // adrenal gland development // inferred from expression pattern /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032349 // positive regulation of aldosterone biosynthetic process // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033080 // immature T cell proliferation in thymus // inferred from electronic annotation /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038030 // non-canonical Wnt signaling pathway via MAPK cascade // inferred from direct assay /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045836 // positive regulation of meiosis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048599 // oocyte development // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060126 // somatotropin secreting cell differentiation // inferred from electronic annotation /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from electronic annotation /// 0060231 // mesenchymal to epithelial transition // inferred from electronic annotation /// 0060748 // tertiary branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from expression pattern /// 0061184 // positive regulation of dermatome development // inferred from direct assay /// 0061205 // paramesonephric duct development // inferred from mutant phenotype /// 0061369 // negative regulation of testicular blood vessel morphogenesis // inferred from mutant phenotype /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0072033 // renal vesicle formation // inferred from electronic annotation /// 0072034 // renal vesicle induction // inferred from electronic annotation /// 0072162 // metanephric mesenchymal cell differentiation // non-traceable author statement /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072273 // metanephric nephron morphogenesis // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000019 // negative regulation of male gonad development // inferred from mutant phenotype /// 2000066 // positive regulation of cortisol biosynthetic process // inferred from direct assay /// 2000225 // negative regulation of testosterone biosynthetic process // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred by curator 208607_s_at NM_030754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030754.1 /DEF=Homo sapiens serum amyloid A2 (SAA2), mRNA. /FEA=CDS /GEN=SAA2 /PROD=serum amyloid A2 /DB_XREF=gi:13540474 /FL=gb:NM_030754.1 NM_030754 serum amyloid A1 /// serum amyloid A2 /// SAA2-SAA4 readthrough SAA1 /// SAA2 /// SAA2-SAA4 6288 /// 6289 /// 100528017 NM_000331 /// NM_001127380 /// NM_001178006 /// NM_001199744 /// NM_030754 /// NM_199161 0006953 // acute-phase response // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // non-traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030593 // neutrophil chemotaxis // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // non-traceable author statement /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from direct assay /// 0050708 // regulation of protein secretion // non-traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050716 // positive regulation of interleukin-1 secretion // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation 208608_s_at NM_021021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021021.1 /DEF=Homo sapiens syntrophin, beta 1 (dystrophin-associated protein A1, 59kD, basic component 1) (SNTB1), mRNA. /FEA=CDS /GEN=SNTB1 /PROD=syntrophin, beta 1 (dystrophin-associatedprotein A1, 59kD, basic component 1) /DB_XREF=gi:11321639 /UG=Hs.95011 syntrophin, beta 1 (dystrophin-associated protein A1, 59kD, basic component 1) /FL=gb:NM_021021.1 NM_021021 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) SNTB1 6641 NM_021021 /// XM_005251031 /// XM_005251032 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 208609_s_at NM_019105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019105.1 /DEF=Homo sapiens tenascin XB (TNXB), mRNA. /FEA=CDS /GEN=TNXB /PROD=tenascin XB /DB_XREF=gi:13811700 /FL=gb:NM_019105.1 NM_019105 tenascin XA (pseudogene) /// tenascin XB TNXA /// TNXB 7146 /// 7148 NM_007116 /// NM_019105 /// NM_032470 /// NR_001284 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 208610_s_at AI655799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655799 /FEA=EST /DB_XREF=gi:4739778 /DB_XREF=est:tt40a10.x1 /CLONE=IMAGE:2243226 /UG=Hs.197114 RNA binding protein; AT-rich element binding factor /FL=gb:AB016092.1 AI655799 serine/arginine repetitive matrix 2 SRRM2 23524 NM_016333 /// XM_005255225 /// XM_005255226 /// XM_005255227 /// XM_006720872 /// XM_006720873 /// XM_006720874 /// XR_243270 /// XR_243271 /// XR_429640 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from direct assay 208611_s_at U83867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U83867.1 /DEF=Human alpha II spectrin mRNA, complete cds. /FEA=mRNA /PROD=alpha II spectrin /DB_XREF=gi:1805279 /UG=Hs.77196 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) /FL=gb:J05243.1 gb:U83867.1 gb:NM_003127.1 U83867 spectrin, alpha, non-erythrocytic 1 SPTAN1 6709 NM_001130438 /// NM_001195532 /// NM_003127 /// XM_006717245 /// XM_006717246 /// XM_006717247 /// XM_006717248 /// XM_006717249 /// XM_006717250 /// XM_006717251 /// XM_006717252 /// XM_006717253 /// XM_006717254 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208612_at D83485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83485.1 /DEF=Homo sapiens mRNA for ER-60 protease, complete cds. /FEA=mRNA /PROD=ER-60 protease /DB_XREF=gi:1208426 /UG=Hs.289101 glucose regulated protein, 58kD /FL=gb:U42068.1 gb:D83485.1 gb:D16234.1 gb:NM_005313.1 D83485 protein disulfide isomerase family A, member 3 PDIA3 2923 NM_005313 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006457 // protein folding // not recorded /// 0006457 // protein folding // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006621 // protein retention in ER lumen // traceable author statement /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004629 // phospholipase C activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208613_s_at AV712733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV712733 /FEA=EST /DB_XREF=gi:10732039 /DB_XREF=est:AV712733 /CLONE=DCAACE01 /UG=Hs.81008 filamin B, beta (actin-binding protein-278) /FL=gb:AF043045.1 gb:AF042166.1 gb:M62994.1 gb:NM_001457.1 AV712733 filamin B, beta FLNB 2317 NM_001164317 /// NM_001164318 /// NM_001164319 /// NM_001457 /// XM_005264977 /// XM_005264978 /// XM_005264981 /// XM_005264982 /// XM_006713067 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208614_s_at M62994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M62994.1 /DEF=Homo sapiens thyroid autoantigen (truncated actin-binding protein) mRNA, complete cds. /FEA=mRNA /PROD=thyroid autoantigen /DB_XREF=gi:349450 /UG=Hs.81008 filamin B, beta (actin-binding protein-278) /FL=gb:AF043045.1 gb:AF042166.1 gb:M62994.1 gb:NM_001457.1 M62994 filamin B, beta FLNB 2317 NM_001164317 /// NM_001164318 /// NM_001164319 /// NM_001457 /// XM_005264977 /// XM_005264978 /// XM_005264981 /// XM_005264982 /// XM_006713067 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208615_s_at BF795101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF795101 /FEA=EST /DB_XREF=gi:12100155 /DB_XREF=est:602256433F1 /CLONE=IMAGE:4339496 /UG=Hs.82911 protein tyrosine phosphatase type IVA, member 2 /FL=gb:U48297.1 gb:NM_003479.1 gb:AF208850.1 BF795101 protein tyrosine phosphatase type IVA, member 2 PTP4A2 8073 NM_001195100 /// NM_001195101 /// NM_003479 /// NM_080391 /// NM_080392 /// XM_005271229 /// XM_005271230 /// XM_005271231 /// XM_005271232 /// XM_006710927 /// XM_006710928 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 208616_s_at U48297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U48297.1 /DEF=Homo sapiens protein tyrosine phosphatase PTPCAAX2 (hPTPCAAX2) mRNA, complete cds. /FEA=mRNA /GEN=hPTPCAAX2 /PROD=protein tyrosine phosphatase PTPCAAX2 /DB_XREF=gi:1777756 /UG=Hs.82911 protein tyrosine phosphatase type IVA, member 2 /FL=gb:U48297.1 gb:NM_003479.1 gb:AF208850.1 U48297 protein tyrosine phosphatase type IVA, member 2 PTP4A2 8073 NM_001195100 /// NM_001195101 /// NM_003479 /// NM_080391 /// NM_080392 /// XM_005271229 /// XM_005271230 /// XM_005271231 /// XM_005271232 /// XM_006710927 /// XM_006710928 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 208617_s_at AF208850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF208850.1 /DEF=Homo sapiens BM-008 mRNA, complete cds. /FEA=mRNA /PROD=BM-008 /DB_XREF=gi:7582287 /UG=Hs.82911 protein tyrosine phosphatase type IVA, member 2 /FL=gb:U48297.1 gb:NM_003479.1 gb:AF208850.1 AF208850 protein tyrosine phosphatase type IVA, member 2 PTP4A2 8073 NM_001195100 /// NM_001195101 /// NM_003479 /// NM_080391 /// NM_080392 /// XM_005271229 /// XM_005271230 /// XM_005271231 /// XM_005271232 /// XM_006710927 /// XM_006710928 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 208619_at L40326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L40326.1 /DEF=Homo sapiens Hepatitis B virus X-associated protein 1 mRNA, complete cds. /FEA=mRNA /PROD=X-associated protein 1 /DB_XREF=gi:695361 /UG=Hs.108327 damage-specific DNA binding protein 1 (127kD) /FL=gb:U18299.1 gb:U32986.1 gb:NM_001923.2 gb:L40326.1 L40326 damage-specific DNA binding protein 1, 127kDa DDB1 1642 NM_001923 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1901990 // regulation of mitotic cell cycle phase transition // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 208620_at U24223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24223.1 /DEF=Human alpha-CP1 mRNA, complete cds. /FEA=mRNA /GEN=alpha-CP1 /PROD=alpha-CP1 /DB_XREF=gi:1215670 /UG=Hs.2853 poly(rC)-binding protein 1 /FL=gb:U24223.1 gb:NM_006196.1 U24223 poly(rC) binding protein 1 PCBP1 5093 NM_006196 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208621_s_at BF663141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF663141 /FEA=EST /DB_XREF=gi:11937036 /DB_XREF=est:602145063F1 /CLONE=IMAGE:4308686 /UG=Hs.155191 villin 2 (ezrin) /FL=gb:J05021.1 gb:AL162086.1 gb:NM_003379.2 BF663141 ezrin EZR 7430 NM_001111077 /// NM_003379 /// XM_006715561 0002066 // columnar/cuboidal epithelial cell development // inferred from sequence or structural similarity /// 0002066 // columnar/cuboidal epithelial cell development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010966 // regulation of phosphate transport // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0032006 // regulation of TOR signaling // inferred from direct assay /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030315 // T-tubule // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044393 // microspike // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation /// 0097454 // Schwann cell microvillus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042289 // MHC class II protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 208622_s_at AA670344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA670344 /FEA=EST /DB_XREF=gi:2631843 /DB_XREF=est:ad16b08.s1 /CLONE=IMAGE:878391 /UG=Hs.155191 villin 2 (ezrin) /FL=gb:J05021.1 gb:AL162086.1 gb:NM_003379.2 AA670344 ezrin EZR 7430 NM_001111077 /// NM_003379 /// XM_006715561 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from direct assay /// 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030315 // T-tubule // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044393 // microspike // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation /// 0097454 // Schwann cell microvillus // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 208623_s_at J05021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J05021.1 /DEF=Human cytovillin 2 (VIL2) mRNA, complete cds. /FEA=mRNA /GEN=VIL2 /DB_XREF=gi:340216 /UG=Hs.155191 villin 2 (ezrin) /FL=gb:J05021.1 gb:AL162086.1 gb:NM_003379.2 J05021 ezrin EZR 7430 NM_001111077 /// NM_003379 /// XM_006715561 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from direct assay /// 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030315 // T-tubule // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044393 // microspike // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation /// 0097454 // Schwann cell microvillus // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 208624_s_at BE966878 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966878 /FEA=EST /DB_XREF=gi:11772751 /DB_XREF=est:601660888R1 /CLONE=IMAGE:3915909 /UG=Hs.211568 eukaryotic translation initiation factor 4 gamma, 1 /FL=gb:AF104913.1 BE966878 eukaryotic translation initiation factor 4 gamma, 1 EIF4G1 1981 NM_001194946 /// NM_001194947 /// NM_001291157 /// NM_004953 /// NM_182917 /// NM_198241 /// NM_198242 /// NM_198244 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208625_s_at AF104913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF104913.1 /DEF=Homo sapiens eukaryotic protein synthesis initiation factor mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic protein synthesis initiation factor /DB_XREF=gi:3941723 /UG=Hs.211568 eukaryotic translation initiation factor 4 gamma, 1 /FL=gb:AF104913.1 AF104913 eukaryotic translation initiation factor 4 gamma, 1 EIF4G1 1981 NM_001194946 /// NM_001194947 /// NM_001291157 /// NM_004953 /// NM_182917 /// NM_198241 /// NM_198242 /// NM_198244 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208626_s_at BC001913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001913.1 /DEF=Homo sapiens, Similar to membrane protein of cholinergic synaptic vesicles, clone MGC:2671, mRNA, complete cds. /FEA=mRNA /PROD=Similar to membrane protein of cholinergicsynaptic vesicles /DB_XREF=gi:12804920 /UG=Hs.157236 membrane protein of cholinergic synaptic vesicles /FL=gb:BC001913.1 gb:NM_006373.1 BC001913 vesicle amine transport 1 VAT1 10493 NM_006373 0010637 // negative regulation of mitochondrial fusion // inferred from mutant phenotype /// 0016049 // cell growth // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 208627_s_at BE966374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966374 /FEA=EST /DB_XREF=gi:11771720 /DB_XREF=est:601660422R1 /CLONE=IMAGE:3906197 /UG=Hs.74497 nuclease sensitive element binding protein 1 /FL=gb:BC002411.1 BE966374 Y box binding protein 1 YBX1 4904 NM_004559 /// XM_005270904 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208628_s_at BC002411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002411.1 /DEF=Homo sapiens, Similar to Y box protein 1, clone MGC:8655, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Y box protein 1 /DB_XREF=gi:12803206 /UG=Hs.74497 nuclease sensitive element binding protein 1 /FL=gb:BC002411.1 BC002411 Y box binding protein 1 YBX1 4904 NM_004559 /// XM_005270904 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208629_s_at BG472176 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG472176 /FEA=EST /DB_XREF=gi:13404550 /DB_XREF=est:602513910F1 /CLONE=IMAGE:4645587 /UG=Hs.75860 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit /FL=gb:NM_000182.1 gb:D16480.1 gb:U04627.1 BG472176 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit HADHA 3030 NM_000182 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016507 // mitochondrial fatty acid beta-oxidation multienzyme complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003985 // acetyl-CoA C-acetyltransferase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from electronic annotation /// 0016509 // long-chain-3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 208630_at AI972144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI972144 /FEA=EST /DB_XREF=gi:5768970 /DB_XREF=est:wr63b03.x1 /CLONE=IMAGE:2492333 /UG=Hs.75860 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit /FL=gb:NM_000182.1 gb:D16480.1 gb:U04627.1 AI972144 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit HADHA 3030 NM_000182 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016507 // mitochondrial fatty acid beta-oxidation multienzyme complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003985 // acetyl-CoA C-acetyltransferase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from electronic annotation /// 0016509 // long-chain-3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 208631_s_at U04627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04627.1 /DEF=Human 78 kDa gastrin-binding protein mRNA, complete cds. /FEA=mRNA /PROD=78 kDa gastrin-binding protein /DB_XREF=gi:595266 /UG=Hs.75860 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit /FL=gb:NM_000182.1 gb:D16480.1 gb:U04627.1 U04627 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit HADHA 3030 NM_000182 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016507 // mitochondrial fatty acid beta-oxidation multienzyme complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003985 // acetyl-CoA C-acetyltransferase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from electronic annotation /// 0016509 // long-chain-3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 208632_at AL578551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL578551 /FEA=EST /DB_XREF=gi:12942733 /DB_XREF=est:AL578551 /CLONE=CS0DK001YG01 (3 prime) /UG=Hs.5094 ring finger protein 10 /FL=gb:AB027196.1 AL578551 ring finger protein 10 RNF10 9921 NM_014868 /// XM_005254013 /// XM_005254014 /// XM_006719717 /// XR_243026 /// XR_243027 /// XR_429123 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 208633_s_at W61052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W61052 /FEA=EST /DB_XREF=gi:1367812 /DB_XREF=est:zd29g11.r1 /CLONE=IMAGE:342116 /UG=Hs.108258 actin binding protein; macrophin (microfilament and actin filament cross-linker protein) /FL=gb:AB029290.1 W61052 microtubule-actin crosslinking factor 1 MACF1 23499 NM_012090 /// NM_033044 /// XM_005270694 /// XM_005270695 /// XM_005270696 /// XM_005270697 /// XM_005270698 /// XM_005270700 /// XM_006710519 /// XM_006710520 /// XM_006710521 /// XM_006710522 /// XM_006710523 /// XM_006710524 /// XM_006710525 /// XM_006710526 /// XM_006710527 /// XM_006710528 /// XM_006710529 /// XM_006710530 /// XM_006710531 /// XM_006710532 /// XM_006710533 /// XM_006710534 /// XM_006710535 /// XM_006710536 /// XM_006710537 /// XM_006710538 /// XM_006710539 /// XM_006710540 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010632 // regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // non-traceable author statement 208634_s_at AB029290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB029290.1 /DEF=Homo sapiens mRNA for actin binding protein ABP620, complete cds. /FEA=mRNA /GEN=abp620 /PROD=actin binding protein ABP620 /DB_XREF=gi:5821433 /UG=Hs.108258 actin binding protein; macrophin (microfilament and actin filament cross-linker protein) /FL=gb:AB029290.1 AB029290 microtubule-actin crosslinking factor 1 MACF1 23499 NM_012090 /// NM_033044 /// XM_005270694 /// XM_005270695 /// XM_005270696 /// XM_005270697 /// XM_005270698 /// XM_005270700 /// XM_006710519 /// XM_006710520 /// XM_006710521 /// XM_006710522 /// XM_006710523 /// XM_006710524 /// XM_006710525 /// XM_006710526 /// XM_006710527 /// XM_006710528 /// XM_006710529 /// XM_006710530 /// XM_006710531 /// XM_006710532 /// XM_006710533 /// XM_006710534 /// XM_006710535 /// XM_006710536 /// XM_006710537 /// XM_006710538 /// XM_006710539 /// XM_006710540 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010632 // regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // non-traceable author statement 208635_x_at BF976260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF976260 /FEA=EST /DB_XREF=gi:12343475 /DB_XREF=est:602245139F1 /CLONE=IMAGE:4336329 /UG=Hs.158164 ATP-binding cassette, sub-family B (MDRTAP), member 2 /FL=gb:BC001849.1 BF976260 nascent polypeptide-associated complex alpha subunit NACA 4666 NM_001113201 /// NM_001113202 /// NM_001113203 /// NM_005594 /// NR_045277 /// XM_006719412 /// XM_006719413 /// XM_006719414 /// XM_006719415 /// XM_006719416 /// XM_006719417 /// XM_006719418 /// XM_006719419 /// XM_006719420 /// XM_006719421 0003231 // cardiac ventricle development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 1901227 // negative regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 1901228 // positive regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005854 // nascent polypeptide-associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from sequence or structural similarity 208636_at AI082078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI082078 /FEA=EST /DB_XREF=gi:3418870 /DB_XREF=est:oz52g10.x1 /CLONE=IMAGE:1679010 /UG=Hs.119000 actinin, alpha 1 /FL=gb:NM_001102.2 gb:BC003576.1 AI082078 actinin, alpha 1 ACTN1 87 NM_001102 /// NM_001130004 /// NM_001130005 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0042995 // cell projection // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 208637_x_at BC003576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003576.1 /DEF=Homo sapiens, actinin, alpha 1, clone MGC:2358, mRNA, complete cds. /FEA=mRNA /PROD=actinin, alpha 1 /DB_XREF=gi:13097755 /UG=Hs.119000 actinin, alpha 1 /FL=gb:NM_001102.2 gb:BC003576.1 BC003576 actinin, alpha 1 ACTN1 87 NM_001102 /// NM_001130004 /// NM_001130005 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0042995 // cell projection // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 208638_at BE910010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE910010 /FEA=EST /DB_XREF=gi:10406176 /DB_XREF=est:601498050F1 /CLONE=IMAGE:3899869 /UG=Hs.182429 protein disulfide isomerase-related protein /FL=gb:BC001312.1 BE910010 protein disulfide isomerase family A, member 6 PDIA6 10130 NM_001282704 /// NM_001282705 /// NM_001282706 /// NM_001282707 /// NM_005742 /// XM_005246145 /// XM_006711856 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043277 // apoptotic cell clearance // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 208639_x_at BC001312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001312.1 /DEF=Homo sapiens, protein disulfide isomerase-related protein, clone MGC:5517, mRNA, complete cds. /FEA=mRNA /PROD=protein disulfide isomerase-related protein /DB_XREF=gi:12654930 /UG=Hs.182429 protein disulfide isomerase-related protein /FL=gb:BC001312.1 BC001312 protein disulfide isomerase family A, member 6 PDIA6 10130 NM_001282704 /// NM_001282705 /// NM_001282706 /// NM_001282707 /// NM_005742 /// XM_005246145 /// XM_006711856 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043277 // apoptotic cell clearance // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay 208640_at BG292367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG292367 /FEA=EST /DB_XREF=gi:13051102 /DB_XREF=est:602386268F1 /CLONE=IMAGE:4515137 /UG=Hs.173737 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) /FL=gb:BC004247.1 gb:M29870.1 gb:M31467.1 gb:NM_006908.2 BG292367 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) RAC1 5879 NM_006908 /// NM_018890 /// NM_198829 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002093 // auditory receptor cell morphogenesis // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010310 // regulation of hydrogen peroxide metabolic process // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021831 // embryonic olfactory bulb interneuron precursor migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from genetic interaction /// 0030041 // actin filament polymerization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031529 // ruffle organization // inferred from direct assay /// 0031529 // ruffle organization // traceable author statement /// 0032707 // negative regulation of interleukin-23 production // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0043652 // engulfment of apoptotic cell // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0048532 // anatomical structure arrangement // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048870 // cell motility // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0051668 // localization within membrane // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060263 // regulation of respiratory burst // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0097178 // ruffle assembly // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0051022 // Rho GDP-dissociation inhibitor binding // inferred from sequence or structural similarity 208641_s_at BC004247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004247.1 /DEF=Homo sapiens, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), clone MGC:10547, mRNA, complete cds. /FEA=mRNA /PROD=ras-related C3 botulinum toxin substrate 1 (rhofamily, small GTP binding protein Rac1) /DB_XREF=gi:13279010 /UG=Hs.173737 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) /FL=gb:BC004247.1 gb:M29870.1 gb:M31467.1 gb:NM_006908.2 BC004247 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) RAC1 5879 NM_006908 /// NM_018890 /// NM_198829 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002093 // auditory receptor cell morphogenesis // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010310 // regulation of hydrogen peroxide metabolic process // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021831 // embryonic olfactory bulb interneuron precursor migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from genetic interaction /// 0030041 // actin filament polymerization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031529 // ruffle organization // inferred from direct assay /// 0031529 // ruffle organization // traceable author statement /// 0032707 // negative regulation of interleukin-23 production // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0043652 // engulfment of apoptotic cell // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0048532 // anatomical structure arrangement // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048870 // cell motility // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0051668 // localization within membrane // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060263 // regulation of respiratory burst // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0097178 // ruffle assembly // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0051022 // Rho GDP-dissociation inhibitor binding // inferred from sequence or structural similarity 208642_s_at AA205834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA205834 /FEA=EST /DB_XREF=gi:1801206 /DB_XREF=est:zq53g12.s1 /CLONE=IMAGE:645382 /UG=Hs.84981 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD) /FL=gb:NM_021141.2 gb:J04977.1 gb:M30938.1 AA205834 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) XRCC5 7520 NM_021141 /// XM_005246836 /// XM_005246837 0000723 // telomere maintenance // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071475 // cellular hyperosmotic salinity response // inferred from electronic annotation /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000783 // nuclear telomere cap complex // traceable author statement /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0043564 // Ku70:Ku80 complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from mutant phenotype 208643_s_at J04977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04977.1 /DEF=Human Ku autoimmune antigen gene, complete cds. /FEA=mRNA /GEN=G22P1 /DB_XREF=gi:186791 /UG=Hs.84981 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD) /FL=gb:NM_021141.2 gb:J04977.1 gb:M30938.1 J04977 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) XRCC5 7520 NM_021141 /// XM_005246836 /// XM_005246837 0000723 // telomere maintenance // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071475 // cellular hyperosmotic salinity response // inferred from electronic annotation /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000783 // nuclear telomere cap complex // traceable author statement /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0043564 // Ku70:Ku80 complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from mutant phenotype 208644_at M32721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M32721.1 /DEF=Human poly(ADP-ribose) polymerase mRNA, complete cds. /FEA=mRNA /GEN=PPOL /DB_XREF=gi:190266 /UG=Hs.177766 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) /FL=gb:NM_001618.2 gb:M18112.1 gb:M32721.1 gb:J03473.1 M32721 poly (ADP-ribose) polymerase 1 PARP1 142 NM_001618 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030225 // macrophage differentiation // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0040009 // regulation of growth rate // inferred from electronic annotation /// 0042769 // DNA damage response, detection of DNA damage // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from electronic annotation /// 0070212 // protein poly-ADP-ribosylation // inferred from direct assay /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051287 // NAD binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from electronic annotation 208645_s_at AF116710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116710.1 /DEF=Homo sapiens PRO2640 mRNA, complete cds. /FEA=mRNA /PROD=PRO2640 /DB_XREF=gi:7959918 /UG=Hs.244621 ribosomal protein S14 /FL=gb:BC001126.1 gb:BC003401.1 gb:NM_005617.1 gb:AF116710.1 AF116710 ribosomal protein S14 RPS14 6208 NM_001025070 /// NM_001025071 /// NM_005617 /// XM_006714790 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000028 // ribosomal small subunit assembly // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from sequence or structural similarity /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 208646_at AF116710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116710.1 /DEF=Homo sapiens PRO2640 mRNA, complete cds. /FEA=mRNA /PROD=PRO2640 /DB_XREF=gi:7959918 /UG=Hs.244621 ribosomal protein S14 /FL=gb:BC001126.1 gb:BC003401.1 gb:NM_005617.1 gb:AF116710.1 AF116710 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000028 // ribosomal small subunit assembly // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from sequence or structural similarity /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 208647_at AA872727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA872727 /FEA=EST /DB_XREF=gi:2968849 /DB_XREF=est:ob11c12.s1 /CLONE=IMAGE:1323382 /UG=Hs.48876 farnesyl-diphosphate farnesyltransferase 1 /FL=gb:L06070.1 gb:L06105.1 gb:NM_004462.1 AA872727 farnesyl-diphosphate farnesyltransferase 1 FDFT1 2222 NM_001287742 /// NM_001287743 /// NM_001287744 /// NM_001287745 /// NM_001287747 /// NM_001287748 /// NM_001287749 /// NM_001287750 /// NM_001287751 /// NM_001287756 /// NM_004462 /// XM_006716247 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045338 // farnesyl diphosphate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004310 // farnesyl-diphosphate farnesyltransferase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016765 // transferase activity, transferring alkyl or aryl (other than methyl) groups // inferred from electronic annotation /// 0051996 // squalene synthase activity // inferred from electronic annotation 208648_at W60953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W60953 /FEA=EST /DB_XREF=gi:1367731 /DB_XREF=est:zc98b12.s1 /CLONE=IMAGE:339167 /UG=Hs.106357 valosin-containing protein /FL=gb:AF100752.1 gb:NM_007126.2 W60953 valosin containing protein VCP 7415 NM_007126 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0019985 // translesion synthesis // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0030970 // retrograde protein transport, ER to cytosol // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0045184 // establishment of protein localization // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070842 // aggresome assembly // inferred from electronic annotation /// 1903006 // positive regulation of protein K63-linked deubiquitination // inferred from direct assay /// 1903007 // positive regulation of Lys63-specific deubiquitinase activity // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035800 // deubiquitinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 208649_s_at AF100752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100752.1 /DEF=Homo sapiens transitional endoplasmic reticulum ATPase mRNA, complete cds. /FEA=mRNA /PROD=transitional endoplasmic reticulum ATPase /DB_XREF=gi:5410289 /UG=Hs.106357 valosin-containing protein /FL=gb:AF100752.1 gb:NM_007126.2 AF100752 valosin containing protein VCP 7415 NM_007126 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0019985 // translesion synthesis // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0030970 // retrograde protein transport, ER to cytosol // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0045184 // establishment of protein localization // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070842 // aggresome assembly // inferred from electronic annotation /// 1903006 // positive regulation of protein K63-linked deubiquitination // inferred from direct assay /// 1903007 // positive regulation of Lys63-specific deubiquitinase activity // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035800 // deubiquitinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 208650_s_at BG327863 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG327863 /FEA=EST /DB_XREF=gi:13134301 /DB_XREF=est:602426876F1 /CLONE=IMAGE:4564675 /UG=Hs.286124 CD24 antigen (small cell lung carcinoma cluster 4 antigen) /FL=gb:M58664.1 gb:L33930.1 gb:NM_013230.1 BG327863 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 208651_x_at M58664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M58664.1 /DEF=Homo sapiens CD24 signal transducer mRNA, complete cds. /FEA=mRNA /PROD=signal transducer CD24 /DB_XREF=gi:180167 /UG=Hs.286124 CD24 antigen (small cell lung carcinoma cluster 4 antigen) /FL=gb:M58664.1 gb:L33930.1 gb:NM_013230.1 M58664 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 208652_at BC000400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000400.1 /DEF=Homo sapiens, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, clone MGC:8533, mRNA, complete cds. /FEA=mRNA /PROD=protein phosphatase 2 (formerly 2A), catalyticsubunit, alpha isoform /DB_XREF=gi:12653262 /UG=Hs.91773 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform /FL=gb:BC000400.1 gb:BC002657.1 gb:J03804.1 gb:M36951.1 gb:NM_002715.1 BC000400 protein phosphatase 2, catalytic subunit, alpha isozyme PPP2CA 5515 NM_002715 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000188 // inactivation of MAPK activity // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006275 // regulation of DNA replication // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006470 // protein dephosphorylation // traceable author statement /// 0006672 // ceramide metabolic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // non-traceable author statement /// 0030111 // regulation of Wnt signaling pathway // non-traceable author statement /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0031952 // regulation of protein autophosphorylation // inferred from electronic annotation /// 0040008 // regulation of growth // non-traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from mutant phenotype 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 208653_s_at AF263279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF263279.1 /DEF=Homo sapiens CD164 mRNA, complete cds. /FEA=CDS /PROD=CD164 /DB_XREF=gi:9230740 /UG=Hs.43910 CD164 antigen, sialomucin /FL=gb:AF299341.1 gb:AF299343.1 gb:AF263279.1 AF263279 CD164 molecule, sialomucin CD164 8763 NM_001142401 /// NM_001142402 /// NM_001142403 /// NM_001142404 /// NM_006016 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0030097 // hemopoiesis // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208654_s_at BF669455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF669455 /FEA=EST /DB_XREF=gi:11943350 /DB_XREF=est:602120159F1 /CLONE=IMAGE:4277366 /UG=Hs.43910 CD164 antigen, sialomucin /FL=gb:AF299341.1 gb:AF299343.1 gb:AF263279.1 BF669455 CD164 molecule, sialomucin CD164 8763 NM_001142401 /// NM_001142402 /// NM_001142403 /// NM_001142404 /// NM_006016 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0030097 // hemopoiesis // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208655_at BG530368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG530368 /FEA=EST /DB_XREF=gi:13521905 /DB_XREF=est:602559112F1 /CLONE=IMAGE:4697115 /UG=Hs.79933 cyclin I /FL=gb:D50310.1 gb:BC000420.1 gb:BC004975.1 gb:NM_006835.1 gb:AF135162.1 BG530368 cyclin I CCNI 10983 NM_006835 0007283 // spermatogenesis // non-traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 208656_s_at AF135162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF135162.1 /DEF=Homo sapiens cyclin I (CYC1) mRNA, complete cds. /FEA=mRNA /GEN=CYC1 /PROD=cyclin I /DB_XREF=gi:7259481 /UG=Hs.79933 cyclin I /FL=gb:D50310.1 gb:BC000420.1 gb:BC004975.1 gb:NM_006835.1 gb:AF135162.1 AF135162 cyclin I CCNI 10983 NM_006835 0007283 // spermatogenesis // non-traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 208657_s_at AF142408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF142408.1 /DEF=Homo sapiens cell division control protein septin D1 mRNA, complete cds. /FEA=mRNA /PROD=cell division control protein septin D1 /DB_XREF=gi:11055010 /UG=Hs.181002 MLL septin-like fusion /FL=gb:AF142408.1 gb:AF142569.1 AF142408 septin 9 SEPT9 10801 NM_001113491 /// NM_001113492 /// NM_001113493 /// NM_001113494 /// NM_001113495 /// NM_001113496 /// NM_001293695 /// NM_001293696 /// NM_001293697 /// NM_001293698 /// NM_006640 /// XM_005256959 /// XM_005256960 /// XM_005256961 /// XM_005256962 /// XM_006721643 /// XM_006721644 0006184 // GTP catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 208658_at BC000425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000425.1 /DEF=Homo sapiens, protein disulfide isomerase related protein (calcium-binding protein, intestinal-related), clone MGC:8346, mRNA, complete cds. /FEA=mRNA /PROD=protein disulfide isomerase related protein(calcium-binding protein, intestinal-related) /DB_XREF=gi:12653312 /UG=Hs.93659 protein disulfide isomerase related protein (calcium-binding protein, intestinal-related) /FL=gb:BC000425.1 gb:BC001928.1 BC000425 protein disulfide isomerase family A, member 4 PDIA4 9601 NM_004911 /// XM_006716185 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded /// 0003756 // protein disulfide isomerase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208659_at AF034607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF034607.1 /DEF=Homo sapiens chloride channel ABP mRNA, complete cds. /FEA=mRNA /PROD=chloride channel ABP /DB_XREF=gi:4426566 /UG=Hs.74276 chloride intracellular channel 1 /FL=gb:U93205.1 gb:AF034607.1 gb:AF109197.1 gb:NM_001288.2 AF034607 chloride intracellular channel 1 CLIC1 1192 NM_001287593 /// NM_001287594 /// NM_001288 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 208660_at BC000105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000105.1 /DEF=Homo sapiens, Similar to CG14740 gene product, clone MGC:2503, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG14740 gene product /DB_XREF=gi:12652712 /UG=Hs.239760 citrate synthase /FL=gb:BC000105.1 gb:AF047042.1 gb:NM_004077.1 BC000105 citrate synthase CS 1431 NM_004077 /// NM_198324 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004108 // citrate (Si)-synthase activity // inferred from direct assay /// 0004108 // citrate (Si)-synthase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation 208661_s_at AW510696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW510696 /FEA=EST /DB_XREF=gi:7148774 /DB_XREF=est:hc89f12.x1 /CLONE=IMAGE:2907215 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:D84294.1 AW510696 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208662_s_at AI885338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885338 /FEA=EST /DB_XREF=gi:5590502 /DB_XREF=est:wl92e09.x1 /CLONE=IMAGE:2432392 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:D84294.1 AI885338 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208663_s_at AI652848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652848 /FEA=EST /DB_XREF=gi:4736827 /DB_XREF=est:wb40a04.x1 /CLONE=IMAGE:2308110 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:D84294.1 AI652848 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208664_s_at AU131711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU131711 /FEA=EST /DB_XREF=gi:10992065 /DB_XREF=est:AU131711 /CLONE=NT2RP3003092 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:D84294.1 AU131711 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208666_s_at BE866412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE866412 /FEA=EST /DB_XREF=gi:10315097 /DB_XREF=est:601678647F1 /CLONE=IMAGE:3961522 /UG=Hs.119222 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein) /FL=gb:U17714.1 gb:AF116650.1 BE866412 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) ST13 6767 NM_001278589 /// NM_003932 0006457 // protein folding // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0061084 // negative regulation of protein refolding // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 208667_s_at U17714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17714.1 /DEF=Homo sapiens putative tumor suppressor ST13 (ST13) mRNA, complete cds. /FEA=mRNA /GEN=ST13 /PROD=putative tumor suppressor ST13 /DB_XREF=gi:4049267 /UG=Hs.119222 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein) /FL=gb:U17714.1 gb:AF116650.1 U17714 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) ST13 6767 NM_001278589 /// NM_003932 0006457 // protein folding // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0061084 // negative regulation of protein refolding // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 208668_x_at BC003689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003689.1 /DEF=Homo sapiens, high-mobility group (nonhistone chromosomal) protein 17, clone MGC:5301, mRNA, complete cds. /FEA=mRNA /PROD=high-mobility group (nonhistone chromosomal)protein 17 /DB_XREF=gi:13277559 /UG=Hs.181163 high-mobility group (nonhistone chromosomal) protein 17 /FL=gb:BC003689.1 gb:M12623.1 BC003689 high mobility group nucleosomal binding domain 2 HMGN2 3151 NM_005517 0006325 // chromatin organization // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208669_s_at AF109873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109873.1 /DEF=Homo sapiens retinoblastoma protein-associated protein mRNA, complete cds. /FEA=mRNA /PROD=retinoblastoma protein-associated protein /DB_XREF=gi:11415000 /UG=Hs.75847 CREBBPEP300 inhibitory protein 1 /FL=gb:AF109873.1 gb:AF274947.1 gb:AF274951.1 gb:AF092135.1 gb:NM_014335.1 AF109873 EP300 interacting inhibitor of differentiation 1 EID1 23741 NM_014335 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from direct assay /// 0035065 // regulation of histone acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0035034 // histone acetyltransferase regulator activity // inferred from direct assay /// 0035035 // histone acetyltransferase binding // inferred from direct assay 208670_s_at AF274951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274951.1 /DEF=Homo sapiens PNAS-26 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-26 /DB_XREF=gi:12751066 /UG=Hs.75847 CREBBPEP300 inhibitory protein 1 /FL=gb:AF109873.1 gb:AF274947.1 gb:AF274951.1 gb:AF092135.1 gb:NM_014335.1 AF274951 EP300 interacting inhibitor of differentiation 1 EID1 23741 NM_014335 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from direct assay /// 0035065 // regulation of histone acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0035034 // histone acetyltransferase regulator activity // inferred from direct assay /// 0035035 // histone acetyltransferase binding // inferred from direct assay 208671_at AF164794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF164794.1 /DEF=Homo sapiens Diff33 protein homolog mRNA, complete cds. /FEA=mRNA /PROD=Diff33 protein homolog /DB_XREF=gi:8895090 /UG=Hs.146668 KIAA1253 protein /FL=gb:AF164794.1 AF164794 serine incorporator 1 SERINC1 57515 NM_020755 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006658 // phosphatidylserine metabolic process // inferred from sequence or structural similarity /// 0006665 // sphingolipid metabolic process // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0015825 // L-serine transport // inferred from sequence or structural similarity /// 0051347 // positive regulation of transferase activity // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015194 // L-serine transmembrane transporter activity // inferred from sequence or structural similarity 208672_s_at BC000914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000914.1 /DEF=Homo sapiens, splicing factor, arginineserine-rich 3, clone MGC:5205, mRNA, complete cds. /FEA=mRNA /PROD=splicing factor, arginineserine-rich 3 /DB_XREF=gi:12654192 /UG=Hs.167460 splicing factor, arginineserine-rich 3 /FL=gb:BC000914.1 gb:AF107405.1 BC000914 serine/arginine-rich splicing factor 3 SRSF3 6428 NM_003017 /// NR_036610 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208673_s_at AF107405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF107405.1 /DEF=Homo sapiens pre-mRNA splicing factor (SFRS3) mRNA, complete cds. /FEA=mRNA /GEN=SFRS3 /PROD=pre-mRNA splicing factor /DB_XREF=gi:5531903 /UG=Hs.167460 splicing factor, arginineserine-rich 3 /FL=gb:BC000914.1 gb:AF107405.1 AF107405 serine/arginine-rich splicing factor 3 SRSF3 6428 NM_003017 /// NR_036610 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208674_x_at BC002594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002594.1 /DEF=Homo sapiens, dolichyl-diphosphooligosaccharide-protein glycosyltransferase, clone MGC:2191, mRNA, complete cds. /FEA=mRNA /PROD=dolichyl-diphosphooligosaccharide-proteinglycosyltransferase /DB_XREF=gi:12803530 /UG=Hs.34789 dolichyl-diphosphooligosaccharide-protein glycosyltransferase /FL=gb:BC002594.1 gb:D29643.1 gb:NM_005216.1 BC002594 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) DDOST 1650 NM_005216 0006412 // translation // traceable author statement /// 0006486 // protein glycosylation // inferred from sequence or structural similarity /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred by curator /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0034097 // response to cytokine // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004576 // oligosaccharyl transferase activity // inferred from sequence or structural similarity /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred by curator /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 208675_s_at D29643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D29643.1 /DEF=Human mRNA for KIAA0115 gene, complete cds. /FEA=mRNA /GEN=KIAA0115 /DB_XREF=gi:473936 /UG=Hs.34789 dolichyl-diphosphooligosaccharide-protein glycosyltransferase /FL=gb:BC002594.1 gb:D29643.1 gb:NM_005216.1 D29643 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) DDOST 1650 NM_005216 0006412 // translation // traceable author statement /// 0006486 // protein glycosylation // inferred from sequence or structural similarity /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred by curator /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0034097 // response to cytokine // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004576 // oligosaccharyl transferase activity // inferred from sequence or structural similarity /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred by curator /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 208676_s_at U87954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87954.1 /DEF=Human erbB3 binding protein EBP1 mRNA, complete cds. /FEA=mRNA /GEN=EBP1 /PROD=erbB3 binding protein EBP1 /DB_XREF=gi:4099505 /UG=Hs.5181 proliferation-associated 2G4, 38kD /FL=gb:BC001951.1 gb:U59435.1 gb:U87954.1 gb:NM_006191.1 U87954 proliferation-associated 2G4, 38kDa PA2G4 5036 NM_006191 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208677_s_at AL550657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL550657 /FEA=EST /DB_XREF=gi:12887837 /DB_XREF=est:AL550657 /CLONE=CS0DI058YI15 (5 prime) /UG=Hs.74631 basigin (OK blood group) /FL=gb:M87879.1 gb:L20471.1 gb:D45131.1 gb:L10240.1 gb:NM_001728.1 AL550657 basigin (Ok blood group) BSG 682 NM_001728 /// NM_198589 /// NM_198590 /// NM_198591 /// XM_005259619 0006090 // pyruvate metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from electronic annotation 208678_at BC004443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004443.1 /DEF=Homo sapiens, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD, clone MGC:4040, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 31kD /DB_XREF=gi:13325247 /UG=Hs.77805 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD /FL=gb:BC004443.1 gb:NM_001696.1 BC004443 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 ATP6V1E1 529 NM_001039366 /// NM_001039367 /// NM_001696 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 208679_s_at AF279893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279893.1 /DEF=Homo sapiens PNAS-139 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-139 /DB_XREF=gi:12751114 /UG=Hs.83583 actin related protein 23 complex, subunit 2 (34 kD) /FL=gb:BC000590.1 gb:AF279893.1 AF279893 actin related protein 2/3 complex, subunit 2, 34kDa ARPC2 10109 NM_005731 /// NM_152862 /// XM_006712173 0006928 // cellular component movement // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from electronic annotation /// 0035650 // AP-1 adaptor complex binding // inferred from electronic annotation /// 0071933 // Arp2/3 complex binding // inferred from electronic annotation 208680_at L19184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L19184.1 /DEF=Human natural killer cell enhancing factor (NKEFA) mRNA, complete cds. /FEA=mRNA /GEN=NKEFA /PROD=enhancer protein /DB_XREF=gi:440305 /UG=Hs.180909 peroxiredoxin 1 /FL=gb:L19184.1 gb:NM_002574.1 L19184 peroxiredoxin 1 PRDX1 5052 NM_001202431 /// NM_002574 /// NM_181696 /// NM_181697 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001895 // retina homeostasis // inferred from expression pattern /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 208682_s_at AF126181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF126181.1 /DEF=Homo sapiens breast cancer-associated gene 1 protein (BCG1) mRNA, complete cds. /FEA=mRNA /GEN=BCG1 /PROD=breast cancer-associated gene 1 protein /DB_XREF=gi:4732088 /UG=Hs.4943 hepatocellular carcinoma associated protein; breast cancer associated gene 1 /FL=gb:NM_006787.1 gb:BC000304.1 gb:U92544.1 gb:AF126181.1 gb:AF128527.1 gb:AF128528.1 AF126181 melanoma antigen family D, 2 MAGED2 10916 NM_014599 /// NM_177433 /// NM_201222 0016020 // membrane // inferred from direct assay 208683_at M23254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M23254.1 /DEF=Human Ca2-activated neutral protease large subunit (CANP) mRNA, complete cds. /FEA=mRNA /GEN=CANP /PROD=neutral protease large subunit /DB_XREF=gi:511636 /UG=Hs.76288 calpain 2, (mII) large subunit /FL=gb:NM_001748.3 gb:M23254.1 gb:AF261089.1 M23254 calpain 2, (m/II) large subunit CAPN2 824 NM_001146068 /// NM_001748 0001666 // response to hypoxia // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred by curator /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // traceable author statement /// 0031143 // pseudopodium // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208684_at U24105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24105.1 /DEF=Homo sapiens coatomer protein (COPA) mRNA, complete cds. /FEA=mRNA /GEN=COPA /PROD=coatomer protein /DB_XREF=gi:1638873 /UG=Hs.75887 coatomer protein complex, subunit alpha /FL=gb:U24105.1 gb:NM_004371.2 U24105 coatomer protein complex, subunit alpha COPA 1314 NM_001098398 /// NM_004371 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030157 // pancreatic juice secretion // inferred from direct assay /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208685_x_at AA902767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA902767 /FEA=EST /DB_XREF=gi:3037890 /DB_XREF=est:ok72a04.s1 /CLONE=IMAGE:1519470 /UG=Hs.75243 bromodomain-containing 2 /FL=gb:NM_005104.2 gb:M80613.1 gb:D42040.1 AA902767 bromodomain containing 2 BRD2 6046 NM_001113182 /// NM_001199455 /// NM_001199456 /// NM_001291986 /// NM_005104 /// NR_037625 /// XR_241911 /// XR_246967 /// XR_247375 /// XR_247406 /// XR_247427 0006334 // nucleosome assembly // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 208686_s_at D42040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D42040.1 /DEF=Human mRNA for KIAA9001 gene, complete cds. /FEA=mRNA /GEN=KIAA9001 /DB_XREF=gi:577292 /UG=Hs.75243 bromodomain-containing 2 /FL=gb:NM_005104.2 gb:M80613.1 gb:D42040.1 D42040 bromodomain containing 2 BRD2 6046 NM_001113182 /// NM_001199455 /// NM_001199456 /// NM_001291986 /// NM_005104 /// NR_037625 /// XR_241911 /// XR_246967 /// XR_247375 /// XR_247406 /// XR_247427 0006334 // nucleosome assembly // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 208687_x_at AF352832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF352832.1 /DEF=Homo sapiens constitutive heat shock protein 70 (HSC70) mRNA, complete cds. /FEA=mRNA /GEN=HSC70 /PROD=constitutive heat shock protein 70 /DB_XREF=gi:13273303 /UG=Hs.180414 heat shock 70kD protein 8 /FL=gb:AF352832.1 gb:NM_006597.1 AF352832 heat shock 70kDa protein 8 /// small nucleolar RNA, C/D box 14C /// small nucleolar RNA, C/D box 14D HSPA8 /// SNORD14C /// SNORD14D 3312 /// 85389 /// 85390 NM_006597 /// NM_153201 /// NR_001453 /// NR_001454 /// XM_006718831 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1902904 // negative regulation of fibril organization // inferred from direct assay 0000974 // Prp19 complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 208688_x_at U78525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78525.1 /DEF=Homo sapiens eukaryotic translation initiation factor (eIF3) mRNA, complete cds. /FEA=mRNA /GEN=eIF3 /PROD=eukaryotic translation initiation factor /DB_XREF=gi:2558667 /UG=Hs.57783 eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) /FL=gb:U78525.1 U78525 eukaryotic translation initiation factor 3, subunit B EIF3B 8662 NM_001037283 /// NM_003751 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // traceable author statement 208689_s_at BC003560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003560.1 /DEF=Homo sapiens, ribophorin II, clone MGC:1817, mRNA, complete cds. /FEA=mRNA /PROD=ribophorin II /DB_XREF=gi:13097707 /UG=Hs.75722 ribophorin II /FL=gb:BC003560.1 gb:NM_002951.1 BC003560 ribophorin II RPN2 6185 NM_001135771 /// NM_002951 /// XM_005260491 /// XM_006723849 /// XM_006723850 /// XM_006723851 /// XM_006723852 0006412 // translation // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation 208690_s_at BC000915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000915.1 /DEF=Homo sapiens, Similar to LIM protein, clone MGC:5344, mRNA, complete cds. /FEA=mRNA /PROD=Similar to LIM protein /DB_XREF=gi:12654194 /UG=Hs.75807 PDZ and LIM domain 1 (elfin) /FL=gb:BC000915.1 BC000915 PDZ and LIM domain 1 PDLIM1 9124 NM_020992 0001666 // response to hypoxia // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208691_at BC001188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001188.1 /DEF=Homo sapiens, transferrin receptor (p90, CD71), clone MGC:3151, mRNA, complete cds. /FEA=mRNA /PROD=transferrin receptor (p90, CD71) /DB_XREF=gi:12654696 /UG=Hs.77356 transferrin receptor (p90, CD71) /FL=gb:BC001188.1 gb:M11507.1 BC001188 transferrin receptor TFRC 7037 NM_001128148 /// NM_003234 0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0097286 // iron ion import // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004998 // transferrin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208692_at U14990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U14990.1 /DEF=Human XP1PO ribosomal protein S3 (rpS3) mRNA, complete cds. /FEA=mRNA /GEN=rpS3 /PROD=ribosomal protein S3 /DB_XREF=gi:555940 /UG=Hs.252259 ribosomal protein S3 /FL=gb:BC003137.1 gb:NM_001005.1 gb:U14990.1 gb:U14991.1 gb:U14992.1 U14990 ribosomal protein S3 RPS3 6188 NM_001005 /// NM_001256802 /// NM_001260506 /// NM_001260507 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045738 // negative regulation of DNA repair // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from mutant phenotype /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902546 // positive regulation of DNA N-glycosylase activity // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071159 // NF-kappaB complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0004519 // endonuclease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0051536 // iron-sulfur cluster binding // non-traceable author statement 208693_s_at D30658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D30658.1 /DEF=Human T-cell mRNA for glycyl tRNA synthetase, complete cds. /FEA=mRNA /PROD=glycyl tRNA synthetase /DB_XREF=gi:577711 /UG=Hs.75280 glycyl-tRNA synthetase /FL=gb:D30658.1 gb:U09587.1 gb:NM_002047.1 D30658 glycyl-tRNA synthetase GARS 2617 NM_002047 /// XM_006715686 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006426 // glycyl-tRNA aminoacylation // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004820 // glycine-tRNA ligase activity // inferred from direct assay /// 0004820 // glycine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay 208694_at U47077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U47077.5 /DEF=Homo sapiens DNA-dependent protein kinase catalytic subunit (DNA-PKcs) mRNA, complete cds. /FEA=mRNA /GEN=DNA-PKcs /PROD=DNA-dependent protein kinase catalytic subunit /DB_XREF=gi:13570016 /UG=Hs.155637 protein kinase, DNA-activated, catalytic polypeptide /FL=gb:U47077.5 gb:NM_006904.5 U47077 protein kinase, DNA-activated, catalytic polypeptide PRKDC 5591 NM_001081640 /// NM_006904 0000723 // telomere maintenance // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0072431 // signal transduction involved in mitotic G1 DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208695_s_at BC001019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001019.1 /DEF=Homo sapiens, ribosomal protein L39, clone MGC:1636, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L39 /DB_XREF=gi:12654388 /UG=Hs.300141 ribosomal protein L39 /FL=gb:BC001019.1 gb:U57846.1 BC001019 ribosomal protein L39 RPL39 6170 NM_001000 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement 208696_at AF275798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF275798.1 /DEF=Homo sapiens PNAS-102 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-102 /DB_XREF=gi:10834761 /UG=Hs.1600 chaperonin containing TCP1, subunit 5 (epsilon) /FL=gb:AF275798.1 AF275798 chaperonin containing TCP1, subunit 5 (epsilon) CCT5 22948 NM_012073 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0031681 // G-protein beta-subunit binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 208697_s_at BC000734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000734.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 3, subunit 6 (48kD), clone MGC:2060, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 3,subunit 6 (48kD) /DB_XREF=gi:12653884 /UG=Hs.106673 eukaryotic translation initiation factor 3, subunit 6 (48kD) /FL=gb:BC000734.1 gb:U62962.1 gb:U54562.1 gb:U85947.1 gb:U94175.1 gb:NM_001568.1 BC000734 eukaryotic translation initiation factor 3, subunit E EIF3E 3646 NM_001568 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // non-traceable author statement 0000785 // chromatin // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 208698_s_at L14599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14599.1 /DEF=Human mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:348238 /UG=Hs.172207 non-POU-domain-containing, octamer-binding /FL=gb:BC002364.1 gb:U89867.1 gb:L14599.1 gb:U02493.1 L14599 non-POU domain containing, octamer-binding NONO 4841 NM_001145408 /// NM_001145409 /// NM_001145410 /// NM_007363 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208699_x_at BF696840 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF696840 /FEA=EST /DB_XREF=gi:11982248 /DB_XREF=est:602125377F1 /CLONE=IMAGE:4282458 /UG=Hs.89643 transketolase (Wernicke-Korsakoff syndrome) /FL=gb:U55017.1 gb:L12711.1 gb:NM_001064.1 BF696840 transketolase TKT 7086 NM_001064 /// NM_001135055 /// NM_001135056 /// NM_001258028 /// NR_047579 /// NR_047580 /// XM_006713319 0005975 // carbohydrate metabolic process // traceable author statement /// 0005999 // xylulose biosynthetic process // traceable author statement /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009052 // pentose-phosphate shunt, non-oxidative branch // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046166 // glyceraldehyde-3-phosphate biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004802 // transketolase activity // not recorded /// 0004802 // transketolase activity // inferred from direct assay /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay 208700_s_at L12711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12711.1 /DEF=Homo sapiens transketolase (tk) mRNA, complete cds. /FEA=mRNA /GEN=tk /PROD=transketolase /DB_XREF=gi:388890 /UG=Hs.89643 transketolase (Wernicke-Korsakoff syndrome) /FL=gb:U55017.1 gb:L12711.1 gb:NM_001064.1 L12711 transketolase TKT 7086 NM_001064 /// NM_001135055 /// NM_001135056 /// NM_001258028 /// NR_047579 /// NR_047580 /// XM_006713319 0005975 // carbohydrate metabolic process // traceable author statement /// 0005999 // xylulose biosynthetic process // traceable author statement /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009052 // pentose-phosphate shunt, non-oxidative branch // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046166 // glyceraldehyde-3-phosphate biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004802 // transketolase activity // not recorded /// 0004802 // transketolase activity // inferred from direct assay /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay 208701_at BC000373 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000373.1 /DEF=Homo sapiens, Similar to amyloid beta (A4) precursor-like protein 2, clone MGC:8371, mRNA, complete cds. /FEA=mRNA /PROD=Similar to amyloid beta (A4) precursor-likeprotein 2 /DB_XREF=gi:12653210 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:BC000373.1 BC000373 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 208702_x_at AI525212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI525212 /FEA=EST /DB_XREF=gi:4439347 /DB_XREF=est:pt1.1-2.A08.r /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:BC000373.1 AI525212 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 208703_s_at BG427393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG427393 /FEA=EST /DB_XREF=gi:13333995 /DB_XREF=est:602499110F1 /CLONE=IMAGE:4612562 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:BC000373.1 BG427393 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 208704_x_at BC000373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000373.1 /DEF=Homo sapiens, Similar to amyloid beta (A4) precursor-like protein 2, clone MGC:8371, mRNA, complete cds. /FEA=mRNA /PROD=Similar to amyloid beta (A4) precursor-likeprotein 2 /DB_XREF=gi:12653210 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:BC000373.1 BC000373 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 208705_s_at BG481972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG481972 /FEA=EST /DB_XREF=gi:13414251 /DB_XREF=est:602526894F1 /CLONE=IMAGE:4650406 /UG=Hs.286236 eukaryotic translation initiation factor 5 /FL=gb:AL080102.1 BG481972 eukaryotic translation initiation factor 5 EIF5 1983 NM_001969 /// NM_183004 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208706_s_at AK026933 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026933.1 /DEF=Homo sapiens cDNA: FLJ23280 fis, clone HEP07194. /FEA=mRNA /DB_XREF=gi:10439907 /UG=Hs.286236 eukaryotic translation initiation factor 5 /FL=gb:AL080102.1 AK026933 eukaryotic translation initiation factor 5 EIF5 1983 NM_001969 /// NM_183004 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208707_at BE552334 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE552334 /FEA=EST /DB_XREF=gi:9794026 /DB_XREF=est:hy06c06.x1 /CLONE=IMAGE:3196522 /UG=Hs.286236 eukaryotic translation initiation factor 5 /FL=gb:AL080102.1 BE552334 eukaryotic translation initiation factor 5 EIF5 1983 NM_001969 /// NM_183004 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208708_x_at AL080102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080102.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564N1916 (from clone DKFZp564N1916); complete cds. /FEA=mRNA /GEN=DKFZp564N1916 /PROD=hypothetical protein /DB_XREF=gi:5262526 /UG=Hs.286236 eukaryotic translation initiation factor 5 /FL=gb:AL080102.1 AL080102 eukaryotic translation initiation factor 5 EIF5 1983 NM_001969 /// NM_183004 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208709_s_at U64898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U64898.1 /DEF=Homo sapiens NRD convertase mRNA, complete cds. /FEA=mRNA /PROD=NRD convertase /DB_XREF=gi:2897866 /UG=Hs.4099 nardilysin (N-arginine dibasic convertase) /FL=gb:U64898.1 U64898 nardilysin (N-arginine dibasic convertase) NRD1 4898 NM_001101662 /// NM_001242361 /// NM_002525 /// XM_005270903 0006508 // proteolysis // non-traceable author statement /// 0007528 // neuromuscular junction development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016477 // cell migration // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0052548 // regulation of endopeptidase activity // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048408 // epidermal growth factor binding // traceable author statement 208710_s_at AI424923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI424923 /FEA=EST /DB_XREF=gi:4270841 /DB_XREF=est:tg19a07.x1 /CLONE=IMAGE:2109204 /UG=Hs.75056 adaptor-related protein complex 3, delta 1 subunit /FL=gb:AF002163.1 AI424923 adaptor-related protein complex 3, delta 1 subunit AP3D1 8943 NM_001077523 /// NM_001261826 /// NM_003938 /// XM_006722932 0006726 // eye pigment biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred by curator /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0048499 // synaptic vesicle membrane organization // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0061088 // regulation of sequestering of zinc ion // inferred from mutant phenotype /// 0072657 // protein localization to membrane // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 208711_s_at BC000076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000076.1 /DEF=Homo sapiens, cyclin D1 (PRAD1: parathyroid adenomatosis 1), clone MGC:2316, mRNA, complete cds. /FEA=mRNA /PROD=cyclin D1 (PRAD1: parathyroid adenomatosis 1) /DB_XREF=gi:12652656 /UG=Hs.82932 cyclin D1 (PRAD1: parathyroid adenomatosis 1) /FL=gb:BC000076.1 gb:M73554.1 BC000076 cyclin D1 CCND1 595 NM_053056 /// XM_006718653 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from electronic annotation /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 208712_at M73554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M73554.1 /DEF=Human bcl-1 mRNA, complete CDS. /FEA=mRNA /GEN=bcl-1 /PROD=bcl-1 /DB_XREF=gi:179364 /UG=Hs.82932 cyclin D1 (PRAD1: parathyroid adenomatosis 1) /FL=gb:BC000076.1 gb:M73554.1 M73554 cyclin D1 CCND1 595 NM_053056 /// XM_006718653 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 208713_at BF724216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF724216 /FEA=EST /DB_XREF=gi:12040125 /DB_XREF=est:bx02c06.y1 /CLONE=bx02c06 /UG=Hs.155218 E1B-55kDa-associated protein 5 /FL=gb:BC002564.1 gb:NM_007040.1 BF724216 heterogeneous nuclear ribonucleoprotein U-like 1 HNRNPUL1 11100 NM_007040 /// NM_144732 /// NM_144733 /// NM_144734 /// XM_005258459 /// XM_005258461 /// XM_005258462 /// XM_005258463 /// XM_005258464 /// XM_005258465 /// XM_005258466 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208714_at AF092131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF092131.1 /DEF=Homo sapiens 51kDa subunit of NADH dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=51kDa subunit of NADH dehydrogenase /DB_XREF=gi:5138911 /UG=Hs.7744 NADH dehydrogenase (ubiquinone) flavoprotein 1 (51kD) /FL=gb:AF053070.1 gb:AF092131.1 gb:NM_007103.1 AF092131 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa NDUFV1 4723 NM_001166102 /// NM_007103 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred by curator /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 208715_at BF002031 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002031 /FEA=EST /DB_XREF=gi:10702306 /DB_XREF=est:7g98a08.x1 /CLONE=IMAGE:3314486 /UG=Hs.93832 putative membrane protein /FL=gb:BC000104.1 gb:AB020980.1 BF002031 transmembrane and coiled-coil domains 1 TMCO1 54499 NM_001256164 /// NM_001256165 /// NM_019026 /// NR_045818 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 208716_s_at AB020980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020980.1 /DEF=Homo sapiens mRNA for putative membrane protein, complete cds. /FEA=mRNA /PROD=membrane protein /DB_XREF=gi:6467174 /UG=Hs.93832 putative membrane protein /FL=gb:BC000104.1 gb:AB020980.1 AB020980 transmembrane and coiled-coil domains 1 TMCO1 54499 NM_001256164 /// NM_001256165 /// NM_019026 /// NR_045818 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 208717_at BC001669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001669.1 /DEF=Homo sapiens, Similar to oxidase (cytochrome c) assembly 1-like, clone MGC:2171, mRNA, complete cds. /FEA=mRNA /PROD=Similar to oxidase (cytochrome c) assembly1-like /DB_XREF=gi:12804516 /UG=Hs.151134 oxidase (cytochrome c) assembly 1-like /FL=gb:BC001669.1 gb:NM_005015.1 BC001669 oxidase (cytochrome c) assembly 1-like OXA1L 5018 NM_005015 0006461 // protein complex assembly // non-traceable author statement /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0009060 // aerobic respiration // non-traceable author statement /// 0032780 // negative regulation of ATPase activity // inferred from mutant phenotype /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0033615 // mitochondrial proton-transporting ATP synthase complex assembly // inferred from mutant phenotype /// 0051205 // protein insertion into membrane // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051354 // negative regulation of oxidoreductase activity // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // non-traceable author statement /// 0097031 // mitochondrial respiratory chain complex I biogenesis // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0097177 // mitochondrial ribosome binding // inferred from direct assay 208718_at Z97056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z97056 /DEF=Human DNA sequence from clone RP3-434P1 on chromosome 22 Contains the KCNJ4 gene for inwardly rectifying potassium channel J4 (hippocampal inward rectifier, HIR, HRK1, HIRK2, KIR2.3), the KDELR3 gene for KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulu... /FEA=mRNA_5 /DB_XREF=gi:2832593 /UG=Hs.6179 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 17 (72kD) /FL=gb:BC000595.1 gb:NM_006386.2 gb:U59321.1 Z97056 DEAD (Asp-Glu-Ala-Asp) box helicase 17 DDX17 10521 NM_001098504 /// NM_001098505 /// NM_006386 /// NM_030881 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208719_s_at U59321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59321.1 /DEF=Human DEAD-box protein p72 (P72) mRNA, complete cds. /FEA=mRNA /GEN=P72 /PROD=DEAD-box protein p72 /DB_XREF=gi:1592564 /UG=Hs.6179 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 17 (72kD) /FL=gb:BC000595.1 gb:NM_006386.2 gb:U59321.1 U59321 DEAD (Asp-Glu-Ala-Asp) box helicase 17 DDX17 10521 NM_001098504 /// NM_001098505 /// NM_006386 /// NM_030881 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208720_s_at AI890947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI890947 /FEA=EST /DB_XREF=gi:5596111 /DB_XREF=est:wm93d01.x1 /CLONE=IMAGE:2443489 /UG=Hs.145696 splicing factor (CC1.3) /FL=gb:L10911.1 AI890947 RNA binding motif protein 39 RBM39 9584 NM_001242599 /// NM_001242600 /// NM_004902 /// NM_184234 /// NM_184237 /// NM_184241 /// NM_184244 /// NR_040722 /// NR_040723 /// NR_040724 /// XM_006723890 /// XM_006723891 /// XM_006723892 /// XM_006723893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208721_s_at BF967271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF967271 /FEA=EST /DB_XREF=gi:12334486 /DB_XREF=est:602287103F1 /CLONE=IMAGE:4374504 /UG=Hs.7101 anaphase-promoting complex subunit 5 /FL=gb:BC001081.1 gb:BC001950.1 gb:AF191339.1 gb:NM_016237.1 BF967271 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 /// XM_005253900 /// XM_006719449 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 208722_s_at BC001081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001081.1 /DEF=Homo sapiens, anaphase-promoting complex subunit 5, clone MGC:2750, mRNA, complete cds. /FEA=mRNA /PROD=anaphase-promoting complex subunit 5 /DB_XREF=gi:12654502 /UG=Hs.7101 anaphase-promoting complex subunit 5 /FL=gb:BC001081.1 gb:BC001950.1 gb:AF191339.1 gb:NM_016237.1 BC001081 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 /// XM_005253900 /// XM_006719449 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 208723_at BC000350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000350.1 /DEF=Homo sapiens, ubiquitin specific protease 11, clone MGC:8620, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin specific protease 11 /DB_XREF=gi:12653164 /UG=Hs.171501 ubiquitin specific protease 11 /FL=gb:BC000350.1 gb:U44839.1 gb:NM_004651.1 BC000350 ubiquitin specific peptidase 11 USP11 8237 NM_004651 /// XM_005272674 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 208724_s_at BC000905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000905.1 /DEF=Homo sapiens, RAB1, member RAS oncogene family, clone MGC:5233, mRNA, complete cds. /FEA=mRNA /PROD=RAB1, member RAS oncogene family /DB_XREF=gi:12654174 /UG=Hs.3642 RAB1, member RAS oncogene family /FL=gb:BC000905.1 BC000905 RAB1A, member RAS oncogene family RAB1A 5861 NM_004161 /// NM_015543 /// XM_005264468 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030252 // growth hormone secretion // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0072606 // interleukin-8 secretion // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 208725_at AL031668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031668 /DEF=Human DNA sequence from clone RP1-64K7 on chromosome 20q11.21-11.23. Contains the EIF2B2 gene for eukaryotic translation initiation factor 2 subunit 2 (beta, 38kD), a putative novel gene, the gene for heterogenous nuclear ribonucleoprotein RALY or... /FEA=mRNA_4 /DB_XREF=gi:11497492 /UG=Hs.12163 eukaryotic translation initiation factor 2, subunit 2 (beta, 38kD ) /FL=gb:BC000461.1 gb:BC000934.2 gb:M29536.1 gb:NM_003908.1 AL031668 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa EIF2S2 8894 NM_003908 /// XM_005260605 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002176 // male germ cell proliferation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208726_s_at BC000461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000461.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 2, subunit 2 (beta, 38kD ), clone MGC:8508, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 2,subunit 2 (beta, 38kD ) /DB_XREF=gi:12653382 /UG=Hs.12163 eukaryotic translation initiation factor 2, subunit 2 (beta, 38kD ) /FL=gb:BC000461.1 gb:BC000934.2 gb:M29536.1 gb:NM_003908.1 BC000461 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa EIF2S2 8894 NM_003908 /// XM_005260605 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002176 // male germ cell proliferation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208727_s_at BC002711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002711.1 /DEF=Homo sapiens, cell division cycle 42 (GTP-binding protein, 25kD), clone MGC:3497, mRNA, complete cds. /FEA=mRNA /PROD=cell division cycle 42 (GTP-binding protein,25kD) /DB_XREF=gi:12803746 /UG=Hs.146409 cell division cycle 42 (GTP-binding protein, 25kD) /FL=gb:BC002711.1 gb:BC003682.1 gb:M57298.1 gb:NM_001791.1 BC002711 cell division cycle 42 CDC42 998 NM_001039802 /// NM_001791 /// NM_044472 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from physical interaction /// 0031424 // keratinization // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048554 // positive regulation of metalloenzyme activity // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0051647 // nucleus localization // inferred from electronic annotation /// 0051683 // establishment of Golgi localization // inferred from sequence or structural similarity /// 0051835 // positive regulation of synapse structural plasticity // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060661 // submandibular salivary gland formation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0071338 // positive regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0072384 // organelle transport along microtubule // inferred from sequence or structural similarity /// 0090135 // actin filament branching // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 208728_s_at BC003682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003682.1 /DEF=Homo sapiens, cell division cycle 42 (GTP-binding protein, 25kD), clone MGC:5044, mRNA, complete cds. /FEA=mRNA /PROD=cell division cycle 42 (GTP-binding protein,25kD) /DB_XREF=gi:13277547 /UG=Hs.146409 cell division cycle 42 (GTP-binding protein, 25kD) /FL=gb:BC002711.1 gb:BC003682.1 gb:M57298.1 gb:NM_001791.1 BC003682 cell division cycle 42 CDC42 998 NM_001039802 /// NM_001791 /// NM_044472 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from physical interaction /// 0031424 // keratinization // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048554 // positive regulation of metalloenzyme activity // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0051647 // nucleus localization // inferred from electronic annotation /// 0051683 // establishment of Golgi localization // inferred from sequence or structural similarity /// 0051835 // positive regulation of synapse structural plasticity // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060661 // submandibular salivary gland formation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0071338 // positive regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0072384 // organelle transport along microtubule // inferred from sequence or structural similarity /// 0090135 // actin filament branching // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 208729_x_at D83043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83043.1 /DEF=Human HLA-B mRNA, allele A*2711, complete cds. /FEA=mRNA /GEN=HLA-B /DB_XREF=gi:1871135 /UG=Hs.77961 major histocompatibility complex, class I, B /FL=gb:U36492.1 gb:U35431.1 gb:L37881.1 gb:U31971.1 gb:L42345.1 gb:U50710.1 gb:L41925.1 gb:L41214.1 gb:U27608.1 gb:U35734.1 gb:U70528.1 gb:U70529.1 gb:U80945.1 gb:U64801.1 gb:U09864.1 gb:M77776.1 gb:M77775.1 gb:L04696.1 gb:D83043.1 gb:M12678.1 gb:L09736.1 gb:L09735.1 gb:M75138.1 gb:M84381.1 gb:M84382.1 gb:M84383.1 gb:M84384.1 gb:M84385.1 gb:M32318.1 gb:M32319.1 gb:M32320.1 gb:M81798.1 gb:L04695.1 gb:M84694.1 gb:U30936.1 gb:AF016641.1 gb:U36392.1 gb:AB008102.1 gb:U75533.1 gb:U57966.1 gb:AF026218.1 gb:L07743.1 gb:U01848.1 gb:U38800.1 gb:U40498.1 gb:U03027.1 gb:U03859.1 gb:L22028.1 gb:U04243.1 gb:U06862.1 gb:L32862.1 gb:L15005.1 gb:L22027.1 gb:L19923.1 gb:L11666.1 gb:L11604.1 gb:L11603.1 gb:L19937.1 gb:L33923.1 gb:AF170577.1 gb:M28205.1 gb:U17107.1 gb:U14943.1 gb:AF130734.1 gb:D25275.1 gb:D50290.1 gb:D50291.1 gb:D50299.1 gb:D50300.1 gb:L38504.1 gb:L36 D83043 major histocompatibility complex, class I, B HLA-B 3106 NM_005514 /// XM_005249043 /// XM_005275100 /// XM_005275238 /// XM_005275376 /// XM_005275377 /// XM_005275535 /// XM_006725904 /// XM_006725905 /// XR_246962 /// XR_427830 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0002667 // regulation of T cell anergy // inferred from mutant phenotype /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032655 // regulation of interleukin-12 production // inferred from mutant phenotype /// 0032675 // regulation of interleukin-6 production // inferred from mutant phenotype /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001198 // regulation of dendritic cell differentiation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 208730_x_at AA535244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA535244 /FEA=EST /DB_XREF=gi:2279497 /DB_XREF=est:nf93a03.s1 /CLONE=IMAGE:927436 /UG=Hs.78305 RAB2, member RAS oncogene family /FL=gb:NM_002865.1 gb:M28213.1 AA535244 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 208731_at AU158062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158062 /FEA=EST /DB_XREF=gi:11019583 /DB_XREF=est:AU158062 /CLONE=PLACE1010787 /UG=Hs.78305 RAB2, member RAS oncogene family /FL=gb:NM_002865.1 gb:M28213.1 AU158062 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 208732_at AI743756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743756 /FEA=EST /DB_XREF=gi:5112044 /DB_XREF=est:wg53e08.x1 /CLONE=IMAGE:2368838 /UG=Hs.78305 RAB2, member RAS oncogene family /FL=gb:NM_002865.1 gb:M28213.1 AI743756 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 208733_at AW301641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301641 /FEA=EST /DB_XREF=gi:6711318 /DB_XREF=est:xr99a07.x1 /CLONE=IMAGE:2768244 /UG=Hs.78305 RAB2, member RAS oncogene family /FL=gb:NM_002865.1 gb:M28213.1 AW301641 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 208734_x_at M28213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M28213.1 /DEF=Homo sapiens GTP-binding protein (RAB2) mRNA, complete cds. /FEA=mRNA /GEN=RAB2 /PROD=GTP-binding protein /DB_XREF=gi:550061 /UG=Hs.78305 RAB2, member RAS oncogene family /FL=gb:NM_002865.1 gb:M28213.1 M28213 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 208735_s_at AF022231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022231.1 /DEF=Homo sapiens unknown protein mRNA, complete cds. /FEA=mRNA /PROD=unknown protein /DB_XREF=gi:4103319 /UG=Hs.180669 conserved gene amplified in osteosarcoma /FL=gb:AF000152.1 gb:AF022231.1 AF022231 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 CTDSP2 10106 NM_005730 /// XM_005268556 0006470 // protein dephosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008420 // CTD phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208736_at AF004561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004561.1 /DEF=Homo sapiens p21-Arc mRNA, complete cds. /FEA=mRNA /PROD=p21-Arc /DB_XREF=gi:2209346 /UG=Hs.6895 actin related protein 23 complex, subunit 3 (21 kD) /FL=gb:AF004561.1 gb:AF006086.1 gb:NM_005719.1 AF004561 actin related protein 2/3 complex, subunit 3, 21kDa ARPC3 10094 NM_001278556 /// NM_001287222 0006928 // cellular component movement // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 208737_at BC003564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003564.1 /DEF=Homo sapiens, ATPase, H+ transporting, lysosomal (vacuolar proton pump), member J, clone MGC:1970, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), member J /DB_XREF=gi:13097719 /UG=Hs.90336 ATPase, H+ transporting, lysosomal (vacuolar proton pump), member J /FL=gb:BC003564.1 gb:AF038954.1 gb:NM_004888.1 BC003564 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 ATP6V1G1 9550 NM_004888 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 208738_x_at AK024823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024823.1 /DEF=Homo sapiens cDNA: FLJ21170 fis, clone CAS10946, highly similar to HSSMT3B Homo sapiens mRNA for SMT3B protein. /FEA=mRNA /DB_XREF=gi:10437226 /UG=Hs.180139 SMT3 (suppressor of mif two 3, yeast) homolog 2 /FL=gb:L76416.1 gb:NM_006937.1 AK024823 small ubiquitin-related modifier 2-like /// small ubiquitin-like modifier 2 /// small ubiquitin-like modifier 3 LOC101929087 /// SUMO2 /// SUMO3 6612 /// 6613 /// 101929087 NM_001005849 /// NM_001286416 /// NM_006936 /// NM_006937 /// XM_005250081 /// XM_005276013 /// XM_005276311 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208739_x_at L76416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76416.1 /DEF=Homo sapiens MIF2 suppressor (HSMT3) mRNA, complete cds. /FEA=mRNA /GEN=HSMT3 /PROD=MIF2 suppressor /DB_XREF=gi:5566605 /UG=Hs.180139 SMT3 (suppressor of mif two 3, yeast) homolog 2 /FL=gb:L76416.1 gb:NM_006937.1 L76416 small ubiquitin-related modifier 2-like /// small ubiquitin-like modifier 2 /// small ubiquitin-like modifier 3 LOC101929087 /// SUMO2 /// SUMO3 6612 /// 6613 /// 101929087 NM_001005849 /// NM_001286416 /// NM_006936 /// NM_006937 /// XM_005250081 /// XM_005276013 /// XM_005276311 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208740_at BF593650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593650 /FEA=EST /DB_XREF=gi:11685974 /DB_XREF=est:nac02d03.x1 /CLONE=IMAGE:3275957 /UG=Hs.23964 sin3-associated polypeptide, 18kD /FL=gb:NM_005870.2 gb:U96915.1 gb:AF153608.1 gb:U78303.1 BF593650 Sin3A-associated protein, 18kDa SAP18 10284 NM_005870 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0061574 // ASAP complex // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208741_at AW274856 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW274856 /FEA=EST /DB_XREF=gi:6661886 /DB_XREF=est:xm61g03.x1 /CLONE=IMAGE:2688724 /UG=Hs.23964 sin3-associated polypeptide, 18kD /FL=gb:NM_005870.2 gb:U96915.1 gb:AF153608.1 gb:U78303.1 AW274856 Sin3A-associated protein, 18kDa SAP18 10284 NM_005870 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0061574 // ASAP complex // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208742_s_at U78303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78303.1 /DEF=Human 2HOR0202 mRNA, complete cds. /FEA=mRNA /PROD=2HOR0202 /DB_XREF=gi:6648546 /UG=Hs.23964 sin3-associated polypeptide, 18kD /FL=gb:NM_005870.2 gb:U96915.1 gb:AF153608.1 gb:U78303.1 U78303 Sin3A-associated protein, 18kDa SAP18 10284 NM_005870 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0061574 // ASAP complex // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208743_s_at BC001359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001359.1 /DEF=Homo sapiens, tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, beta polypeptide, clone MGC:1580, mRNA, complete cds. /FEA=mRNA /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, beta polypeptide /DB_XREF=gi:12655022 /UG=Hs.279920 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, beta polypeptide /FL=gb:BC001359.1 BC001359 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta YWHAB 7529 NM_003404 /// NM_139323 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051220 // cytoplasmic sequestering of protein // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 208744_x_at BG403660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG403660 /FEA=EST /DB_XREF=gi:13297108 /DB_XREF=est:602419382F1 /CLONE=IMAGE:4526180 /UG=Hs.36927 heat shock 105kD /FL=gb:D86956.1 gb:AB003334.1 BG403660 heat shock 105kDa/110kDa protein 1 HSPH1 10808 NM_001286503 /// NM_001286504 /// NM_001286505 /// NM_006644 /// XM_005266236 /// XM_006719757 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0045345 // positive regulation of MHC class I biosynthetic process // traceable author statement /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051135 // positive regulation of NK T cell activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation 208745_at AA917672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA917672 /FEA=EST /DB_XREF=gi:3057562 /DB_XREF=est:on46d09.s1 /CLONE=IMAGE:1559729 /UG=Hs.107476 ATP synthase, H+ transporting, mitochondrial F1F0, subunit g /FL=gb:AF070655.1 AA917672 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G ATP5L 10632 NM_006476 /// NR_033759 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 208746_x_at AF070655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070655.1 /DEF=Homo sapiens F1F0-type ATP synthase subunit g mRNA, complete cds. /FEA=mRNA /PROD=F1F0-type ATP synthase subunit g /DB_XREF=gi:4454685 /UG=Hs.107476 ATP synthase, H+ transporting, mitochondrial F1F0, subunit g /FL=gb:AF070655.1 AF070655 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G ATP5L 10632 NM_006476 /// NR_033759 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 208747_s_at M18767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M18767.1 /DEF=Human complement subcomponent C1s, alpha- and beta-chains, complete cds. /FEA=mRNA /GEN=C1S /DB_XREF=gi:179647 /UG=Hs.169756 complement component 1, s subcomponent /FL=gb:J04080.1 gb:M18767.1 gb:NM_001734.1 M18767 complement component 1, s subcomponent C1S 716 NM_001734 /// NM_201442 /// XM_005253760 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 208748_s_at AA507012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA507012 /FEA=EST /DB_XREF=gi:2243451 /DB_XREF=est:ni04f03.s1 /CLONE=IMAGE:967037 /UG=Hs.179986 flotillin 1 /FL=gb:BC001146.1 gb:AF085357.1 gb:AF089750.2 gb:NM_005803.2 AA507012 flotillin 1 FLOT1 10211 NM_005803 /// XM_005248780 /// XM_005248781 /// XM_005272759 /// XM_005272760 /// XM_005274909 /// XM_005274910 /// XM_005275335 /// XM_005275336 /// XM_005275502 /// XM_005275503 /// XM_006714947 /// XM_006725465 /// XM_006725672 /// XM_006725971 /// XM_006726072 0007409 // axonogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016600 // flotillin complex // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 208749_x_at AF085357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF085357.1 /DEF=Homo sapiens flotillin mRNA, complete cds. /FEA=mRNA /PROD=flotillin /DB_XREF=gi:5114048 /UG=Hs.179986 flotillin 1 /FL=gb:BC001146.1 gb:AF085357.1 gb:AF089750.2 gb:NM_005803.2 AF085357 flotillin 1 FLOT1 10211 NM_005803 /// XM_005248780 /// XM_005248781 /// XM_005272759 /// XM_005272760 /// XM_005274909 /// XM_005274910 /// XM_005275335 /// XM_005275336 /// XM_005275502 /// XM_005275503 /// XM_006714947 /// XM_006725465 /// XM_006725672 /// XM_006725971 /// XM_006726072 0007409 // axonogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016600 // flotillin complex // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 208750_s_at AA580004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA580004 /FEA=EST /DB_XREF=gi:2355331 /DB_XREF=est:nl79c05.s1 /CLONE=IMAGE:1056872 /UG=Hs.74571 ADP-ribosylation factor 1 /FL=gb:M84326.1 gb:M36340.1 gb:AF055002.1 gb:AF052179.1 gb:NM_001658.2 AA580004 ADP-ribosylation factor 1 /// microRNA 3620 ARF1 /// MIR3620 375 /// 100500810 NM_001024226 /// NM_001024227 /// NM_001024228 /// NM_001658 /// NR_037415 0002090 // regulation of receptor internalization // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0034315 // regulation of Arp2/3 complex-mediated actin nucleation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0097061 // dendritic spine organization // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208751_at BC001165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001165.1 /DEF=Homo sapiens, N-ethylmaleimide-sensitive factor attachment protein, alpha, clone MGC:1700, mRNA, complete cds. /FEA=mRNA /PROD=N-ethylmaleimide-sensitive factor attachmentprotein, alpha /DB_XREF=gi:12654654 /UG=Hs.75932 N-ethylmaleimide-sensitive factor attachment protein, alpha /FL=gb:BC001165.1 BC001165 N-ethylmaleimide-sensitive factor attachment protein, alpha NAPA 8775 NM_003827 /// NR_038456 /// NR_038457 /// XM_006723454 /// XM_006723455 /// XM_006723456 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0010807 // regulation of synaptic vesicle priming // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035494 // SNARE complex disassembly // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 208752_x_at AI888672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI888672 /FEA=EST /DB_XREF=gi:5593836 /DB_XREF=est:wn34c03.x1 /CLONE=IMAGE:2447332 /UG=Hs.179662 nucleosome assembly protein 1-like 1 /FL=gb:BC002387.1 gb:AL162068.1 AI888672 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208753_s_at BC002387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002387.1 /DEF=Homo sapiens, nucleosome assembly protein 1-like 1, clone MGC:8688, mRNA, complete cds. /FEA=mRNA /PROD=nucleosome assembly protein 1-like 1 /DB_XREF=gi:12803166 /UG=Hs.179662 nucleosome assembly protein 1-like 1 /FL=gb:BC002387.1 gb:AL162068.1 BC002387 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208754_s_at AL162068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL162068.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762G106 (from clone DKFZp762G106); complete cds. /FEA=mRNA /GEN=DKFZp762G106 /PROD=hypothetical protein /DB_XREF=gi:7328143 /UG=Hs.179662 nucleosome assembly protein 1-like 1 /FL=gb:BC002387.1 gb:AL162068.1 AL162068 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208755_x_at BF312331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF312331 /FEA=EST /DB_XREF=gi:11260131 /DB_XREF=est:601898862F1 /CLONE=IMAGE:4128159 /UG=Hs.181307 H3 histone, family 3A /FL=gb:M11354.1 BF312331 H3 histone, family 3A /// H3 histone, family 3A, pseudogene 4 /// H3 histone, family 3B (H3.3B) H3F3A /// H3F3AP4 /// H3F3B 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208756_at U36764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36764.1 /DEF=Human TGF-beta receptor interacting protein 1 mRNA, complete cds. /FEA=mRNA /PROD=TGF-beta receptor interacting protein 1 /DB_XREF=gi:1036804 /UG=Hs.192023 eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) /FL=gb:U36764.1 gb:BC000413.1 gb:BC003140.1 gb:U39067.1 gb:NM_003757.1 gb:AF116697.1 U36764 eukaryotic translation initiation factor 3, subunit I EIF3I 8668 NM_003757 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 208757_at BC001123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001123.1 /DEF=Homo sapiens, Similar to gp25L2 protein, clone MGC:2142, mRNA, complete cds. /FEA=mRNA /PROD=Similar to gp25L2 protein /DB_XREF=gi:12654574 /UG=Hs.279929 gp25L2 protein /FL=gb:BC001123.1 BC001123 transmembrane emp24 protein transport domain containing 9 TMED9 54732 NM_017510 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0048205 // COPI coating of Golgi vesicle // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction 208758_at D89976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89976.1 /DEF=Homo sapiens mRNA for 5-aminoimidazole-4-carboxamide ribonucleotide transformylase, complete cds. /FEA=mRNA /PROD=5-aminoimidazole-4-carboxamide ribonucleotidetransformylase /DB_XREF=gi:2317691 /UG=Hs.90280 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferaseIMP cyclohydrolase /FL=gb:U37436.1 gb:D82348.1 gb:D89976.1 gb:NM_004044.1 D89976 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ATIC 471 NM_004044 /// XM_006712545 0003360 // brainstem development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009259 // ribonucleotide metabolic process // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046452 // dihydrofolate metabolic process // inferred from electronic annotation /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003937 // IMP cyclohydrolase activity // traceable author statement /// 0004643 // phosphoribosylaminoimidazolecarboxamide formyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 208759_at AF240468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF240468.1 /DEF=Homo sapiens nicastrin mRNA, complete cds. /FEA=mRNA /PROD=nicastrin /DB_XREF=gi:9992877 /UG=Hs.4788 nicastrin /FL=gb:AF240468.1 AF240468 nicastrin NCSTN 23385 NM_001290184 /// NM_001290186 /// NM_015331 /// XM_005245053 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0006508 // proteolysis // non-traceable author statement /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050435 // beta-amyloid metabolic process // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation 208760_at AL031714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031714 /DEF=Human DNA sequence from clone LA16-358B7 on chromosome 16 Contains the UBE21 gene for ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9), and an RPS20 (40S Ribosomal protein S20) pseudogene. Contains ESTs, STSs. GSSs and a putative CpG is... /FEA=mRNA /DB_XREF=gi:4775608 /UG=Hs.84285 ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) /FL=gb:U45328.1 gb:U31933.1 gb:BC000427.1 gb:BC004429.1 gb:U31882.1 gb:U66818.1 gb:U66867.1 gb:U38785.1 gb:NM_003345.1 gb:U29092.1 AL031714 ubiquitin-conjugating enzyme E2I UBE2I 7329 NM_003345 /// NM_194259 /// NM_194260 /// NM_194261 /// XM_005255540 /// XM_005255541 /// XM_006720938 /// XM_006720939 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033145 // positive regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // traceable author statement /// 0001650 // fibrillar center // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0043398 // HLH domain binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 208761_s_at U67122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U67122.1 /DEF=Human ubiquitin-related protein SUMO-1 mRNA, complete cds. /FEA=mRNA /PROD=SUMO-1 /DB_XREF=gi:1762972 /UG=Hs.81424 ubiquitin-like 1 (sentrin) /FL=gb:U61397.1 gb:U38784.1 gb:U72722.1 gb:U67122.1 gb:U83117.1 gb:NM_003352.1 U67122 small ubiquitin-like modifier 1 SUMO1 7341 NM_001005781 /// NM_001005782 /// NM_003352 0006281 // DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030578 // PML body organization // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032880 // regulation of protein localization // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0090204 // protein localization to nuclear pore // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208762_at U83117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U83117.1 /DEF=Human sentrin mRNA, complete cds. /FEA=mRNA /PROD=sentrin /DB_XREF=gi:1769601 /UG=Hs.81424 ubiquitin-like 1 (sentrin) /FL=gb:U61397.1 gb:U38784.1 gb:U72722.1 gb:U67122.1 gb:U83117.1 gb:NM_003352.1 U83117 small ubiquitin-like modifier 1 SUMO1 7341 NM_001005781 /// NM_001005782 /// NM_003352 0006281 // DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030578 // PML body organization // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032880 // regulation of protein localization // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0090204 // protein localization to nuclear pore // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208763_s_at AL110191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL110191.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566A093 (from clone DKFZp566A093); complete cds. /FEA=mRNA /GEN=DKFZp566A093 /PROD=hypothetical protein /DB_XREF=gi:5817105 /UG=Hs.75450 delta sleep inducing peptide, immunoreactor /FL=gb:AF228339.1 gb:AF153603.1 gb:AL110191.1 gb:AF183393.1 AL110191 TSC22 domain family, member 3 TSC22D3 1831 NM_001015881 /// NM_004089 /// NM_198057 /// XM_005262098 /// XM_005262099 /// XM_005262100 /// XM_005262101 /// XM_005262102 /// XM_005262103 /// XM_006724629 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070236 // negative regulation of activation-induced cell death of T cells // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043426 // MRF binding // inferred from electronic annotation 208764_s_at D13119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13119.1 /DEF=Homo sapiens P2 mRNA for ATP synthase subunit c, complete cds. /FEA=mRNA /GEN=P2 /PROD=ATP synthase subunit c precursor /DB_XREF=gi:285909 /UG=Hs.89399 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 /FL=gb:D13119.1 D13119 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) ATP5G2 517 NM_001002031 /// NM_005176 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 208765_s_at NM_005826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005826.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein R (HNRPR), mRNA. /FEA=CDS /GEN=HNRPR /PROD=heterogeneous nuclear ribonucleoprotein R /DB_XREF=gi:5031754 /UG=Hs.15265 heterogeneous nuclear ribonucleoprotein R /FL=gb:BC001449.1 gb:AF000364.1 gb:NM_005826.1 NM_005826 heterogeneous nuclear ribonucleoprotein R HNRNPR 10236 NM_001102397 /// NM_001102398 /// NM_001102399 /// NM_005826 /// XM_005245711 /// XM_005245712 /// XM_005245713 /// XM_005245714 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // non-traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208766_s_at BC001449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001449.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein R, clone MGC:2039, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein R /DB_XREF=gi:12655184 /UG=Hs.15265 heterogeneous nuclear ribonucleoprotein R /FL=gb:BC001449.1 gb:AF000364.1 gb:NM_005826.1 BC001449 heterogeneous nuclear ribonucleoprotein R HNRNPR 10236 NM_001102397 /// NM_001102398 /// NM_001102399 /// NM_005826 /// XM_005245711 /// XM_005245712 /// XM_005245713 /// XM_005245714 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // non-traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208767_s_at AW149681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149681 /FEA=EST /DB_XREF=gi:6197577 /DB_XREF=est:xf41a10.x1 /CLONE=IMAGE:2620602 /UG=Hs.296398 Homo sapiens mRNA; cDNA DKFZp586E1124 (from clone DKFZp586E1124); complete cds /FL=gb:AL136942.1 AW149681 lysosomal protein transmembrane 4 beta LAPTM4B 55353 NM_018407 0006810 // transport // inferred from electronic annotation 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 208768_x_at D17652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D17652.1 /DEF=Human mRNA for HBp15L22, complete cds. /FEA=mRNA /PROD=HBp15L22 /DB_XREF=gi:409069 /UG=Hs.99914 ribosomal protein L22 /FL=gb:D17652.1 D17652 ribosomal protein L22 RPL22 6146 NM_000983 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208769_at AW500473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW500473 /FEA=EST /DB_XREF=gi:7113120 /DB_XREF=est:UI-HF-BN0-akb-e-12-0-UI.r1 /CLONE=IMAGE:3076702 /UG=Hs.278712 eukaryotic translation initiation factor 4E binding protein 2 /FL=gb:BC005057.1 gb:NM_004096.1 gb:L36056.1 AW500473 eukaryotic translation initiation factor 4E binding protein 2 EIF4EBP2 1979 NM_004096 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation 208770_s_at BC005057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005057.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 4E binding protein 2, clone MGC:12944, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 4Ebinding protein 2 /DB_XREF=gi:13477190 /UG=Hs.278712 eukaryotic translation initiation factor 4E binding protein 2 /FL=gb:BC005057.1 gb:NM_004096.1 gb:L36056.1 BC005057 eukaryotic translation initiation factor 4E binding protein 2 EIF4EBP2 1979 NM_004096 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation 208771_s_at J02959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02959.1 /DEF=Human leukotriene A-4 hydrolase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:187174 /UG=Hs.81118 leukotriene A4 hydrolase /FL=gb:J03459.1 gb:J02959.1 gb:NM_000895.1 J02959 uncharacterized LOC101928830 /// leukotriene A4 hydrolase LOC101928830 /// LTA4H 4048 /// 101928830 NM_000895 /// NM_001256643 /// NM_001256644 /// XM_005268871 /// XR_246022 /// XR_246023 /// XR_247857 /// XR_247858 /// XR_253102 /// XR_253103 0006508 // proteolysis // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0043171 // peptide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0004301 // epoxide hydrolase activity // inferred from direct assay /// 0004301 // epoxide hydrolase activity // traceable author statement /// 0004463 // leukotriene-A4 hydrolase activity // inferred from direct assay /// 0004463 // leukotriene-A4 hydrolase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208772_at AU160676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU160676 /FEA=EST /DB_XREF=gi:11022197 /DB_XREF=est:AU160676 /CLONE=Y79AA1002208 /UG=Hs.301226 KIAA1085 protein /FL=gb:AL136943.1 AU160676 ankyrin repeat and KH domain containing 1 /// ANKHD1-EIF4EBP3 readthrough ANKHD1 /// ANKHD1-EIF4EBP3 54882 /// 404734 NM_001197030 /// NM_017747 /// NM_017978 /// NM_020690 /// NM_024668 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // non-traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation /// 0030371 // translation repressor activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208773_s_at AL136943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136943.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586G1024 (from clone DKFZp586G1024); complete cds. /FEA=mRNA /GEN=DKFZp586G1024 /PROD=hypothetical protein /DB_XREF=gi:12053380 /UG=Hs.301226 KIAA1085 protein /FL=gb:AL136943.1 AL136943 ankyrin repeat and KH domain containing 1 /// ANKHD1-EIF4EBP3 readthrough ANKHD1 /// ANKHD1-EIF4EBP3 54882 /// 404734 NM_001197030 /// NM_017747 /// NM_017978 /// NM_020690 /// NM_024668 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // non-traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation /// 0030371 // translation repressor activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208774_at AV700224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700224 /FEA=EST /DB_XREF=gi:10302195 /DB_XREF=est:AV700224 /CLONE=GKCARG01 /UG=Hs.75852 casein kinase 1, delta /FL=gb:BC003558.1 AV700224 casein kinase 1, delta CSNK1D 1453 NM_001893 /// NM_139062 /// NR_110578 /// XM_005256336 /// XM_005256337 /// XR_243518 /// XR_430027 /// XR_430028 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 208775_at D89729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89729.1 /DEF=Homo sapiens mRNA for CRM1 protein, complete cds. /FEA=mRNA /PROD=CRM1 protein /DB_XREF=gi:2626839 /UG=Hs.79090 exportin 1 (CRM1, yeast, homolog) /FL=gb:D89729.1 gb:NM_003400.2 D89729 exportin 1 XPO1 7514 NM_003400 /// XM_005264544 /// XM_005264546 /// XM_006712094 /// XM_006712095 /// XM_006712096 /// XM_006712097 0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010824 // regulation of centrosome duplication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005642 // annulate lamellae // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 208776_at BF432873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432873 /FEA=EST /DB_XREF=gi:11445036 /DB_XREF=est:7n28a02.x1 /CLONE=IMAGE:3565730 /UG=Hs.90744 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 /FL=gb:BC000437.1 gb:BC004430.1 gb:AB003102.1 gb:AF001212.1 gb:NM_002815.1 BF432873 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 PSMD11 5717 NM_001270482 /// NM_002815 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043248 // proteasome assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0048863 // stem cell differentiation // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208777_s_at AF001212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001212.1 /DEF=Homo sapiens 26S proteasome subunit 9 mRNA, complete cds. /FEA=mRNA /PROD=26S proteasome subunit 9 /DB_XREF=gi:2150045 /UG=Hs.90744 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 /FL=gb:BC000437.1 gb:BC004430.1 gb:AB003102.1 gb:AF001212.1 gb:NM_002815.1 AF001212 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 PSMD11 5717 NM_001270482 /// NM_002815 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043248 // proteasome assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0048863 // stem cell differentiation // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208778_s_at BC000665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000665.1 /DEF=Homo sapiens, t-complex 1, clone MGC:2234, mRNA, complete cds. /FEA=mRNA /PROD=t-complex 1 /DB_XREF=gi:12653758 /UG=Hs.4112 t-complex 1 /FL=gb:BC000665.1 BC000665 small nucleolar RNA, H/ACA box 29 /// t-complex 1 SNORA29 /// TCP1 6950 /// 677812 NM_001008897 /// NM_030752 /// NR_002965 0006457 // protein folding // traceable author statement /// 0007021 // tubulin complex assembly // non-traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 208779_x_at L20817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20817.1 /DEF=Homo sapiens tyrosine protein kinase (CAK) gene, complete cds. /FEA=mRNA /GEN=CAK /PROD=tyrosine protein kinase /DB_XREF=gi:306474 /UG=Hs.75562 discoidin domain receptor family, member 1 /FL=gb:L20817.1 L20817 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 /// 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208780_x_at AF154847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF154847.1 /DEF=Homo sapiens 33 kDa Vamp-associated protein (VAMP) mRNA, complete cds. /FEA=mRNA /GEN=VAMP /PROD=33 kDa Vamp-associated protein /DB_XREF=gi:8099349 /UG=Hs.9006 VAMP (vesicle-associated membrane protein)-associated protein A (33kD) /FL=gb:BC002992.1 gb:AF057358.1 gb:AF044670.1 gb:AF086627.1 gb:NM_003574.1 gb:AF154847.1 AF154847 VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa VAPA 9218 NM_003574 /// NM_194434 0006665 // sphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from mutant phenotype /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 208781_x_at AF062483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062483.1 /DEF=Homo sapiens SDP3 mRNA, complete cds. /FEA=mRNA /PROD=SDP3 /DB_XREF=gi:3126978 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1 AF062483 sorting nexin 3 SNX3 8724 NM_003795 /// NM_152827 /// NM_152828 /// XM_005267192 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 208782_at BC000055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000055.1 /DEF=Homo sapiens, follistatin-like 1, clone MGC:1993, mRNA, complete cds. /FEA=mRNA /PROD=follistatin-like 1 /DB_XREF=gi:12652618 /UG=Hs.296267 follistatin-like 1 /FL=gb:BC000055.1 gb:U06863.1 BC000055 follistatin-like 1 FSTL1 11167 NM_007085 0030509 // BMP signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation 208783_s_at AL570661 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL570661 /FEA=EST /DB_XREF=gi:12927188 /DB_XREF=est:AL570661 /CLONE=CS0DI021YG18 (3 prime) /UG=Hs.83532 membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) /FL=gb:M58050.1 AL570661 CD46 molecule, complement regulatory protein CD46 4179 NM_002389 /// NM_153826 /// NM_172350 /// NM_172351 /// NM_172352 /// NM_172353 /// NM_172354 /// NM_172355 /// NM_172356 /// NM_172357 /// NM_172358 /// NM_172359 /// NM_172360 /// NM_172361 0002250 // adaptive immune response // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0032613 // interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035581 // sequestering of extracellular ligand from receptor // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from direct assay /// 0045916 // negative regulation of complement activation // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002079 // inner acrosomal membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 208784_s_at BC001793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001793.1 /DEF=Homo sapiens, clone MGC:3124, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3124) /DB_XREF=gi:12804724 /UG=Hs.281706 sortilin 1 /FL=gb:BC000295.1 gb:BC001789.1 gb:BC001793.1 BC001793 kelch domain containing 3 KLHDC3 116138 NM_001242872 /// NM_057161 /// NR_040101 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from direct assay /// 0006897 // endocytosis // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from mutant phenotype /// 0016050 // vesicle organization // inferred from direct assay /// 0016050 // vesicle organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032509 // endosome transport via multivesicular body sorting pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0032868 // response to insulin // inferred from mutant phenotype /// 0038180 // nerve growth factor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046323 // glucose import // inferred from electronic annotation /// 0046323 // glucose import // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0048227 // plasma membrane to endosome transport // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010465 // nerve growth factor receptor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030379 // neurotensin receptor activity, non-G-protein coupled // inferred from direct assay /// 0048406 // nerve growth factor binding // inferred from physical interaction 208785_s_at BE893893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE893893 /FEA=EST /DB_XREF=gi:10355716 /DB_XREF=est:601436260F1 /CLONE=IMAGE:3921446 /UG=Hs.121849 microtubule-associated proteins 1A1B light chain 3 /FL=gb:AF303888.1 gb:NM_022818.2 gb:AF183417.1 BE893893 microtubule-associated protein 1 light chain 3 beta MAP1LC3B 81631 NM_022818 /// XM_005256184 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0050811 // GABA receptor binding // not recorded 208786_s_at AF183417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF183417.1 /DEF=Homo sapiens microtubule-associated proteins 1A1B light chain 3 mRNA, complete cds. /FEA=mRNA /PROD=microtubule-associated proteins 1A1B lightchain 3 /DB_XREF=gi:9963772 /UG=Hs.121849 microtubule-associated proteins 1A1B light chain 3 /FL=gb:AF303888.1 gb:NM_022818.2 gb:AF183417.1 AF183417 microtubule-associated protein 1 light chain 3 beta MAP1LC3B 81631 NM_022818 /// XM_005256184 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0050811 // GABA receptor binding // not recorded 208787_at BC003375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003375.1 /DEF=Homo sapiens, mitochondrial ribosomal protein L3, clone MGC:5219, mRNA, complete cds. /FEA=mRNA /PROD=mitochondrial ribosomal protein L3 /DB_XREF=gi:13097224 /UG=Hs.79086 mitochondrial ribosomal protein L3 /FL=gb:BC003375.1 gb:NM_007208.1 BC003375 mitochondrial ribosomal protein L3 MRPL3 11222 NM_007208 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208788_at AL136939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136939.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1824 (from clone DKFZp586B1824); complete cds. /FEA=mRNA /GEN=DKFZp586B1824 /PROD=hypothetical protein /DB_XREF=gi:12053372 /UG=Hs.250175 homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 /FL=gb:NM_021814.1 gb:AL136939.1 gb:AF111849.1 gb:AF231981.1 AL136939 ELOVL fatty acid elongase 5 ELOVL5 60481 NM_001242828 /// NM_001242830 /// NM_001242831 /// NM_021814 /// XM_005249266 /// XM_005249267 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034625 // fatty acid elongation, monounsaturated fatty acid // inferred from direct assay /// 0034626 // fatty acid elongation, polyunsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 208789_at BC004295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004295.1 /DEF=Homo sapiens, clone IMAGE:3622356, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3622356) /DB_XREF=gi:13279151 /UG=Hs.29759 RNA POLYMERASE I AND TRANSCRIPT RELEASE FACTOR /FL=gb:AF312393.1 BC004295 polymerase I and transcript release factor PTRF 284119 NM_012232 /// XM_005257242 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // inferred from direct assay /// 0006363 // termination of RNA polymerase I transcription // inferred from direct assay /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0042134 // rRNA primary transcript binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208790_s_at AF312393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312393.1 /DEF=Homo sapiens leucine-zipper protein FKSG13 (FKSG13) mRNA, complete cds. /FEA=mRNA /GEN=FKSG13 /PROD=leucine-zipper protein FKSG13 /DB_XREF=gi:11034808 /UG=Hs.29759 RNA POLYMERASE I AND TRANSCRIPT RELEASE FACTOR /FL=gb:AF312393.1 AF312393 polymerase I and transcript release factor PTRF 284119 NM_012232 /// XM_005257242 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006353 // DNA-templated transcription, termination // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // inferred from direct assay /// 0006363 // termination of RNA polymerase I transcription // inferred from direct assay /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0042134 // rRNA primary transcript binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208791_at M25915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25915.1 /DEF=Human complement cytolysis inhibitor (CLI) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180619 /UG=Hs.75106 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) /FL=gb:J02908.1 gb:M25915.1 gb:M64722.1 gb:NM_001831.1 M25915 clusterin CLU 1191 NM_001831 /// NR_038335 /// NR_045494 /// XM_006716284 0000902 // cell morphogenesis // inferred from direct assay /// 0001774 // microglial cell activation // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0017038 // protein import // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032286 // central nervous system myelin maintenance // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0051788 // response to misfolded protein // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061518 // microglial cell proliferation // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from sequence or structural similarity /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902847 // regulation of neuronal signal transduction // inferred from mutant phenotype /// 1902949 // positive regulation of tau-protein kinase activity // inferred from mutant phenotype /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from mutant phenotype /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042583 // chromaffin granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097418 // neurofibrillary tangle // inferred from direct assay /// 0097440 // apical dendrite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from physical interaction 208792_s_at M25915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25915.1 /DEF=Human complement cytolysis inhibitor (CLI) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180619 /UG=Hs.75106 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) /FL=gb:J02908.1 gb:M25915.1 gb:M64722.1 gb:NM_001831.1 M25915 clusterin CLU 1191 NM_001831 /// NR_038335 /// NR_045494 /// XM_006716284 0000902 // cell morphogenesis // inferred from direct assay /// 0001774 // microglial cell activation // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0017038 // protein import // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032286 // central nervous system myelin maintenance // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0051788 // response to misfolded protein // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061518 // microglial cell proliferation // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from sequence or structural similarity /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902847 // regulation of neuronal signal transduction // inferred from mutant phenotype /// 1902949 // positive regulation of tau-protein kinase activity // inferred from mutant phenotype /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from mutant phenotype /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042583 // chromaffin granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097418 // neurofibrillary tangle // inferred from direct assay /// 0097440 // apical dendrite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from physical interaction 208793_x_at AI744900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744900 /FEA=EST /DB_XREF=gi:5113188 /DB_XREF=est:tr16h01.x1 /CLONE=IMAGE:2218513 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 /FL=gb:NM_003072.1 gb:D26156.1 gb:U29175.1 AI744900 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 208794_s_at D26156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D26156.1 /DEF=Human mRNA for transcriptional activator hSNF2b, complete cds. /FEA=mRNA /PROD=hSNF2b /DB_XREF=gi:505087 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 /FL=gb:NM_003072.1 gb:D26156.1 gb:U29175.1 D26156 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 208795_s_at D55716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D55716.1 /DEF=Human mRNA for P1cdc47, complete cds. /FEA=mRNA /GEN=P1cdc47 /PROD=P1cdc47 /DB_XREF=gi:1255616 /UG=Hs.77152 minichromosome maintenance deficient (S. cerevisiae) 7 /FL=gb:D55716.1 D55716 minichromosome maintenance complex component 7 MCM7 4176 NM_001278595 /// NM_005916 /// NM_182776 /// XM_005250348 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0042555 // MCM complex // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 208796_s_at BC000196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000196.1 /DEF=Homo sapiens, cyclin G1, clone MGC:643, mRNA, complete cds. /FEA=mRNA /PROD=cyclin G1 /DB_XREF=gi:12652880 /UG=Hs.79101 cyclin G1 /FL=gb:L49504.1 gb:U47413.1 gb:BC000196.1 gb:D78341.1 gb:NM_004060.2 BC000196 cyclin G1 CCNG1 900 NM_004060 /// NM_199246 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0006949 // syncytium formation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 208797_s_at AI829170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI829170 /FEA=EST /DB_XREF=gi:5449841 /DB_XREF=est:wk76b03.x1 /CLONE=IMAGE:2421293 /UG=Hs.182982 golgin-67 /FL=gb:NM_015003.1 gb:AF204231.1 AI829170 golgin A8 family, member A GOLGA8A 23015 NM_181077 /// NR_027409 /// XM_006720440 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 208798_x_at AF204231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF204231.1 /DEF=Homo sapiens 88-kDa Golgi protein (GM88) mRNA, complete cds. /FEA=mRNA /GEN=GM88 /PROD=88-kDa Golgi protein /DB_XREF=gi:6808610 /UG=Hs.182982 golgin-67 /FL=gb:NM_015003.1 gb:AF204231.1 AF204231 golgin A8 family, member A GOLGA8A 23015 NM_181077 /// NR_027409 /// XM_006720440 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 208799_at BC004146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004146.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, beta type, 5, clone MGC:2175, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, betatype, 5 /DB_XREF=gi:13278740 /UG=Hs.78596 proteasome (prosome, macropain) subunit, beta type, 5 /FL=gb:BC004146.1 gb:NM_002797.1 gb:D29011.1 BC004146 proteasome (prosome, macropain) subunit, beta type, 5 PSMB5 5693 NM_001130725 /// NM_001144932 /// NM_002797 /// XM_005267871 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 208800_at AV702627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702627 /FEA=EST /DB_XREF=gi:10718957 /DB_XREF=est:AV702627 /CLONE=ADBAHC04 /UG=Hs.237825 signal recognition particle 72kD /FL=gb:AF069765.1 gb:AF077019.1 gb:NM_006947.1 AV702627 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0005047 // signal recognition particle binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208801_at BE856385 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856385 /FEA=EST /DB_XREF=gi:10369357 /DB_XREF=est:7f93h03.x1 /CLONE=IMAGE:3304565 /UG=Hs.237825 signal recognition particle 72kD /FL=gb:AF069765.1 gb:AF077019.1 gb:NM_006947.1 BE856385 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0005047 // signal recognition particle binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208802_at AI493872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI493872 /FEA=EST /DB_XREF=gi:4394875 /DB_XREF=est:qz90a06.x1 /CLONE=IMAGE:2041810 /UG=Hs.237825 signal recognition particle 72kD /FL=gb:AF069765.1 gb:AF077019.1 gb:NM_006947.1 AI493872 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0005047 // signal recognition particle binding // inferred from physical interaction /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208803_s_at AF069765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF069765.1 /DEF=Homo sapiens signal recognition particle 72 (SRP72) mRNA, complete cds. /FEA=mRNA /GEN=SRP72 /PROD=signal recognition particle 72 /DB_XREF=gi:3243032 /UG=Hs.237825 signal recognition particle 72kD /FL=gb:AF069765.1 gb:AF077019.1 gb:NM_006947.1 AF069765 signal recognition particle 72kDa SRP72 6731 NM_001267722 /// NM_006947 /// XM_005265765 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0005047 // signal recognition particle binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208804_s_at AL031681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031681 /DEF=Human DNA sequence from clone 862K6 on chromosome 20q12-13.13. Contains the gene for a protein similar to Drosophila lethal (3) malignant brain tumor (l(3)mbt) protein, the SFRS6 gene for arginineserine-rich splicing factor 6 (SRP55), a 4E-BP2 (4... /FEA=mRNA_3 /DB_XREF=gi:10198606 /UG=Hs.6891 splicing factor, arginineserine-rich 6 /FL=gb:U30828.1 AL031681 serine/arginine-rich splicing factor 6 SRSF6 6431 NM_006275 /// NR_034009 0000380 // alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010837 // regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0045617 // negative regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0061041 // regulation of wound healing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208805_at BC002979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002979.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, alpha type 6, clone MGC:2333, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, alphatype 6 /DB_XREF=gi:12804240 /UG=Hs.74077 proteasome (prosome, macropain) subunit, alpha type, 6 /FL=gb:BC002979.1 BC002979 KIAA0391 /// proteasome (prosome, macropain) subunit, alpha type, 6 KIAA0391 /// PSMA6 5687 /// 9692 NM_001256678 /// NM_001256679 /// NM_001256680 /// NM_001256681 /// NM_001282232 /// NM_001282233 /// NM_001282234 /// NM_002791 /// NM_014672 /// NR_104110 /// XM_005268237 /// XM_006720334 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005839 // proteasome core complex // non-traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from direct assay /// 0019773 // proteasome core complex, alpha-subunit complex // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0004175 // endopeptidase activity // non-traceable author statement /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035639 // purine ribonucleoside triphosphate binding // non-traceable author statement /// 0051059 // NF-kappaB binding // inferred from physical interaction 208806_at BE379542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE379542 /FEA=EST /DB_XREF=gi:9324907 /DB_XREF=est:601238148F1 /CLONE=IMAGE:3610234 /UG=Hs.25601 chromodomain helicase DNA binding protein 3 /FL=gb:U91543.1 BE379542 chromodomain helicase DNA binding protein 3 CHD3 1107 NM_001005271 /// NM_001005273 /// NM_005852 /// XM_005256427 /// XM_005256428 /// XM_005256429 /// XM_005256431 /// XM_006721423 /// XM_006721424 /// XM_006721425 /// XM_006721426 /// XM_006721427 /// XM_006721428 /// XM_006721429 /// XM_006721430 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007051 // spindle organization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0051297 // centrosome organization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208807_s_at U91543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U91543.1 /DEF=Homo sapiens zinc-finger helicase (hZFH) mRNA, complete cds. /FEA=mRNA /GEN=hZFH /PROD=zinc-finger helicase /DB_XREF=gi:3298561 /UG=Hs.25601 chromodomain helicase DNA binding protein 3 /FL=gb:U91543.1 U91543 chromodomain helicase DNA binding protein 3 CHD3 1107 NM_001005271 /// NM_001005273 /// NM_005852 /// XM_005256427 /// XM_005256428 /// XM_005256429 /// XM_005256431 /// XM_006721423 /// XM_006721424 /// XM_006721425 /// XM_006721426 /// XM_006721427 /// XM_006721428 /// XM_006721429 /// XM_006721430 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007051 // spindle organization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0051297 // centrosome organization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208808_s_at BC000903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000903.1 /DEF=Homo sapiens, high-mobility group (nonhistone chromosomal) protein 2, clone MGC:5234, mRNA, complete cds. /FEA=mRNA /PROD=high-mobility group (nonhistone chromosomal)protein 2 /DB_XREF=gi:12654170 /UG=Hs.80684 high-mobility group (nonhistone chromosomal) protein 2 /FL=gb:BC000903.1 gb:BC001063.1 BC000903 high mobility group box 2 HMGB2 3148 NM_001130688 /// NM_001130689 /// NM_002129 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0032075 // positive regulation of nuclease activity // inferred from direct assay /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from mutant phenotype /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from genetic interaction 208809_s_at AL136632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136632.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G182 (from clone DKFZp564G182); complete cds. /FEA=mRNA /GEN=DKFZp564G182 /PROD=hypothetical protein /DB_XREF=gi:12052789 /UG=Hs.173685 hypothetical protein FLJ12619 /FL=gb:AL136632.1 AL136632 chromosome 6 open reading frame 62 C6orf62 81688 NM_030939 /// XM_005249433 0005622 // intracellular // inferred from direct assay 208810_at AF080569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080569.1 /DEF=Homo sapiens DnaJ-like 2 protein (HSJ2) mRNA, complete cds. /FEA=mRNA /GEN=HSJ2 /PROD=DnaJ-like 2 protein /DB_XREF=gi:4322314 /UG=Hs.181195 DnaJ (Hsp40) homolog, subfamily B, member 6 /FL=gb:AL136707.1 gb:BC000177.2 gb:AB014888.1 gb:AF080569.1 gb:NM_005494.1 gb:AF075601.1 gb:AF060703.1 gb:AB015799.1 AF080569 DnaJ (Hsp40) homolog, subfamily B, member 6 /// transmembrane protein 135 DNAJB6 /// TMEM135 10049 /// 65084 NM_001168724 /// NM_005494 /// NM_022918 /// NM_058246 /// NR_033149 /// XM_005249515 /// XM_005249516 /// XM_006715823 /// XM_006718667 /// XM_006718668 0006457 // protein folding // inferred from direct assay /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045109 // intermediate filament organization // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060715 // syncytiotrophoblast cell differentiation involved in labyrinthine layer development // inferred from electronic annotation /// 0060717 // chorion development // inferred from electronic annotation /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 208811_s_at AF080569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080569.1 /DEF=Homo sapiens DnaJ-like 2 protein (HSJ2) mRNA, complete cds. /FEA=mRNA /GEN=HSJ2 /PROD=DnaJ-like 2 protein /DB_XREF=gi:4322314 /UG=Hs.181195 DnaJ (Hsp40) homolog, subfamily B, member 6 /FL=gb:AL136707.1 gb:BC000177.2 gb:AB014888.1 gb:AF080569.1 gb:NM_005494.1 gb:AF075601.1 gb:AF060703.1 gb:AB015799.1 AF080569 DnaJ (Hsp40) homolog, subfamily B, member 6 /// transmembrane protein 135 DNAJB6 /// TMEM135 10049 /// 65084 NM_001168724 /// NM_005494 /// NM_022918 /// NM_058246 /// NR_033149 /// XM_005249515 /// XM_005249516 /// XM_006715823 /// XM_006718667 /// XM_006718668 0006457 // protein folding // inferred from direct assay /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045109 // intermediate filament organization // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060715 // syncytiotrophoblast cell differentiation involved in labyrinthine layer development // inferred from electronic annotation /// 0060717 // chorion development // inferred from electronic annotation /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 208812_x_at BC004489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004489.1 /DEF=Homo sapiens, major histocompatibility complex, class I, C, clone MGC:11039, mRNA, complete cds. /FEA=mRNA /PROD=major histocompatibility complex, class I, C /DB_XREF=gi:13325360 /UG=Hs.277477 major histocompatibility complex, class I, C /FL=gb:NM_002117.1 gb:M99388.1 gb:U06487.1 gb:BC002463.1 gb:BC004489.1 gb:D64145.1 gb:D38526.1 gb:D49552.1 gb:D49819.1 gb:M24097.1 gb:M84171.1 gb:M84172.1 gb:M84173.1 gb:M84174.1 gb:M26429.1 gb:M26430.1 gb:M26431.1 gb:U41420.1 gb:U41386.1 gb:D50852.1 gb:D50853.1 gb:D50854.1 gb:D83031.1 gb:U57028.1 gb:U06695.1 gb:U06696.1 gb:M99389.1 gb:M99390.1 gb:M28160.1 gb:U09853.1 gb:AF168611.1 gb:L38251.1 gb:D31817.1 BC004489 major histocompatibility complex, class I, C HLA-C 3107 NM_001243042 /// NM_002117 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay 208813_at BC000498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000498.1 /DEF=Homo sapiens, glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1), clone MGC:8411, mRNA, complete cds. /FEA=mRNA /PROD=glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1) /DB_XREF=gi:12653452 /UG=Hs.597 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) /FL=gb:BC000498.1 gb:M37400.1 gb:NM_002079.1 BC000498 glutamic-oxaloacetic transaminase 1, soluble GOT1 2805 NM_002079 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006114 // glycerol biosynthetic process // inferred from sequence or structural similarity /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006531 // aspartate metabolic process // inferred from sequence or structural similarity /// 0006532 // aspartate biosynthetic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006595 // polyamine metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0019550 // glutamate catabolic process to aspartate // inferred from electronic annotation /// 0019551 // glutamate catabolic process to 2-oxoglutarate // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from expression pattern /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043648 // dicarboxylic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from expression pattern /// 0055089 // fatty acid homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from direct assay /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from sequence or structural similarity /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // traceable author statement /// 0004609 // phosphatidylserine decarboxylase activity // inferred from electronic annotation /// 0008483 // transaminase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0047801 // L-cysteine:2-oxoglutarate aminotransferase activity // inferred from sequence or structural similarity /// 0080130 // L-phenylalanine:2-oxoglutarate aminotransferase activity // inferred from electronic annotation 208814_at AA043348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA043348 /FEA=EST /DB_XREF=gi:1521422 /DB_XREF=est:zk66b12.s1 /CLONE=IMAGE:487775 /UG=Hs.90093 heat shock 70kD protein 4 /FL=gb:AB023420.1 AA043348 heat shock 70kDa protein 4 HSPA4 3308 NM_002154 /// NM_198431 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 208815_x_at AB023420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB023420.1 /DEF=Homo sapiens mRNA for heat shock protein apg-2, complete cds. /FEA=mRNA /GEN=apg-2 /PROD=apg-2 /DB_XREF=gi:4579908 /UG=Hs.90093 heat shock 70kD protein 4 /FL=gb:AB023420.1 AB023420 heat shock 70kDa protein 4 HSPA4 3308 NM_002154 /// NM_198431 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 208816_x_at M62898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M62898.1 /DEF=Human lipocortin (LIP) 2 pseudogene mRNA, complete cds-like region. /FEA=mRNA /DB_XREF=gi:187147 /UG=Hs.217493 annexin A2 /FL=gb:M62898.1 M62898 annexin A2 pseudogene 2 ANXA2P2 304 NR_003573 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 208817_at BC000419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000419.1 /DEF=Homo sapiens, catechol-O-methyltransferase, clone MGC:8663, mRNA, complete cds. /FEA=mRNA /PROD=catechol-O-methyltransferase /DB_XREF=gi:12653300 /UG=Hs.240013 catechol-O-methyltransferase /FL=gb:BC000419.1 gb:M58525.1 gb:M65212.1 gb:NM_007310.1 gb:NM_000754.2 BC000419 catechol-O-methyltransferase COMT 1312 NM_000754 /// NM_001135161 /// NM_001135162 /// NM_007310 /// XM_005261229 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208818_s_at BC000419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000419.1 /DEF=Homo sapiens, catechol-O-methyltransferase, clone MGC:8663, mRNA, complete cds. /FEA=mRNA /PROD=catechol-O-methyltransferase /DB_XREF=gi:12653300 /UG=Hs.240013 catechol-O-methyltransferase /FL=gb:BC000419.1 gb:M58525.1 gb:M65212.1 gb:NM_007310.1 gb:NM_000754.2 BC000419 catechol-O-methyltransferase COMT 1312 NM_000754 /// NM_001135161 /// NM_001135162 /// NM_007310 /// XM_005261229 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208819_at BC002977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002977.1 /DEF=Homo sapiens, mel transforming oncogene (derived from cell line NK14)- RAB8 homolog, clone MGC:2196, mRNA, complete cds. /FEA=mRNA /PROD=mel transforming oncogene (derived from cellline NK14)- RAB8 homolog /DB_XREF=gi:12804236 /UG=Hs.5947 mel transforming oncogene (derived from cell line NK14)- RAB8 homolog /FL=gb:BC002977.1 gb:NM_005370.2 BC002977 RAB8A, member RAS oncogene family RAB8A 4218 NM_005370 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from direct assay /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048210 // Golgi vesicle fusion to target membrane // inferred from direct assay /// 0051223 // regulation of protein transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation 208820_at AL037339 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037339 /FEA=EST /DB_XREF=gi:5406748 /DB_XREF=est:DKFZp564F1271_s1 /CLONE=DKFZp564F1271 /UG=Hs.740 PTK2 protein tyrosine kinase 2 /FL=gb:L13616.1 AL037339 protein tyrosine kinase 2 PTK2 5747 NM_001199649 /// NM_005607 /// NM_153831 /// XM_005251003 /// XM_005251004 /// XM_005251005 /// XM_005251006 /// XM_005251007 /// XM_005251008 /// XM_005251009 /// XM_005251010 /// XM_005251011 /// XM_005251012 /// XM_005251013 /// XM_005251014 /// XM_006716606 /// XM_006716607 /// XM_006716608 /// XM_006716609 /// XM_006716610 0000165 // MAPK cascade // inferred from electronic annotation /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001890 // placenta development // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010594 // regulation of endothelial cell migration // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0038007 // netrin-activated signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048870 // cell motility // traceable author statement /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008432 // JUN kinase binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation 208821_at J04564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04564.1 /DEF=Human snRNP polypeptide B mRNA, complete cds. /FEA=mRNA /GEN=SNRPB /DB_XREF=gi:190246 /UG=Hs.83753 small nuclear ribonucleoprotein polypeptides B and B1 /FL=gb:J04564.1 gb:NM_003091.1 J04564 small nuclear ribonucleoprotein polypeptides B and B1 SNRPB 6628 NM_003091 /// NM_198216 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071208 // histone pre-mRNA DCP binding // inferred from electronic annotation 208822_s_at U18321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18321.1 /DEF=Human ionizing radiation resistance conferring protein mRNA, complete cds. /FEA=mRNA /PROD=ionizing radiation resistance conferringprotein /DB_XREF=gi:603763 /UG=Hs.159627 death associated protein 3 /FL=gb:U18321.1 U18321 death associated protein 3 DAP3 7818 NM_001199849 /// NM_001199850 /// NM_001199851 /// NM_004632 /// NM_033657 /// XM_005245480 /// XM_005245481 /// XM_005245482 /// XM_006711527 /// XM_006711528 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208823_s_at BE787860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE787860 /FEA=EST /DB_XREF=gi:10209058 /DB_XREF=est:601482876F1 /CLONE=IMAGE:3885379 /UG=Hs.171834 PCTAIRE protein kinase 1 /FL=gb:BC001048.1 BE787860 cyclin-dependent kinase 16 CDK16 5127 NM_001170460 /// NM_006201 /// NM_033018 /// XM_005272614 /// XM_005272615 /// XM_006724534 /// XM_006724535 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208824_x_at BC001048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001048.1 /DEF=Homo sapiens, PCTAIRE protein kinase 1, clone MGC:1330, mRNA, complete cds. /FEA=mRNA /PROD=PCTAIRE protein kinase 1 /DB_XREF=gi:12654444 /UG=Hs.171834 PCTAIRE protein kinase 1 /FL=gb:BC001048.1 BC001048 cyclin-dependent kinase 16 CDK16 5127 NM_001170460 /// NM_006201 /// NM_033018 /// XM_005272614 /// XM_005272615 /// XM_006724534 /// XM_006724535 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208825_x_at U43701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43701.1 /DEF=Human ribosomal protein L23a mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L23a /DB_XREF=gi:1399085 /UG=Hs.184776 ribosomal protein L23a /FL=gb:U43701.1 U43701 ribosomal protein L23a /// small nucleolar RNA, C/D box 42A RPL23A /// SNORD42A 6147 /// 26809 NM_000984 /// NR_000014 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208826_x_at U27143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27143.1 /DEF=Human protein kinase C inhibitor-I cDNA, complete cds. /FEA=mRNA /PROD=protein kinase C inhibitor-I /DB_XREF=gi:862932 /UG=Hs.256697 histidine triad nucleotide-binding protein /FL=gb:BC001287.1 gb:U27143.1 U27143 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 /// NR_073488 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009154 // purine ribonucleotide catabolic process // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from direct assay 208827_at BC000835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000835.1 /DEF=Homo sapiens, Similar to proteasome (prosome, macropain) subunit, beta type 6, clone MGC:5169, mRNA, complete cds. /FEA=mRNA /PROD=Similar to proteasome (prosome, macropain)subunit, beta type 6 /DB_XREF=gi:12654058 /UG=Hs.77060 proteasome (prosome, macropain) subunit, beta type, 6 /FL=gb:BC000835.1 gb:D29012.1 BC000835 proteasome (prosome, macropain) subunit, beta type, 6 PSMB6 5694 NM_001270481 /// NM_002798 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // non-traceable author statement /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 208828_at BC004170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004170.1 /DEF=Homo sapiens, histone fold protein CHRAC17; DNA polymerase epsilon p17 subunit, clone MGC:2725, mRNA, complete cds. /FEA=mRNA /PROD=histone fold protein CHRAC17; DNA polymeraseepsilon p17 subunit /DB_XREF=gi:13278800 /UG=Hs.108112 histone fold protein CHRAC17; DNA polymerase epsilon p17 subunit /FL=gb:BC003166.1 gb:BC004170.1 gb:AF226077.1 gb:NM_017443.1 BC004170 polymerase (DNA directed), epsilon 3, accessory subunit POLE3 54107 NM_001278255 /// NM_017443 /// NR_027261 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0008622 // epsilon DNA polymerase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 208829_at AF029750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029750.1 /DEF=Homo sapiens tapasin (NGS-17) mRNA, complete cds. /FEA=mRNA /GEN=NGS-17 /PROD=tapasin /DB_XREF=gi:2587057 /UG=Hs.179600 TAP binding protein (tapasin) /FL=gb:AF314222.1 gb:AF009510.1 gb:AF029750.1 gb:AB010639.1 gb:NM_003190.1 AF029750 TAP binding protein (tapasin) TAPBP 6892 NM_003190 /// NM_172208 /// NM_172209 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0015833 // peptide transport // traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042886 // amide transport // traceable author statement /// 0050823 // peptide antigen stabilization // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0042824 // MHC class I peptide loading complex // non-traceable author statement /// 0042825 // TAP complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015433 // peptide antigen-transporting ATPase activity // traceable author statement /// 0042288 // MHC class I protein binding // traceable author statement /// 0042605 // peptide antigen binding // traceable author statement /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046978 // TAP1 binding // traceable author statement /// 0046979 // TAP2 binding // inferred from physical interaction /// 0046979 // TAP2 binding // traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 208830_s_at AI494567 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI494567 /FEA=EST /DB_XREF=gi:4395570 /DB_XREF=est:qz16h09.x1 /CLONE=IMAGE:2021729 /UG=Hs.12303 suppressor of Ty (S.cerevisiae) 6 homolog /FL=gb:D79984.1 AI494567 suppressor of Ty 6 homolog (S. cerevisiae) SUPT6H 6830 NM_003170 /// XM_005258026 /// XM_005258027 /// XM_006722042 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0045191 // regulation of isotype switching // inferred from sequence or structural similarity /// 0050684 // regulation of mRNA processing // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208831_x_at D79984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D79984.1 /DEF=Human mRNA for KIAA0162 gene, complete cds. /FEA=mRNA /GEN=KIAA0162 /DB_XREF=gi:1136385 /UG=Hs.12303 suppressor of Ty (S.cerevisiae) 6 homolog /FL=gb:D79984.1 D79984 suppressor of Ty 6 homolog (S. cerevisiae) SUPT6H 6830 NM_003170 /// XM_005258026 /// XM_005258027 /// XM_006722042 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0045191 // regulation of isotype switching // inferred from sequence or structural similarity /// 0050684 // regulation of mRNA processing // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208832_at AW241832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW241832 /FEA=EST /DB_XREF=gi:6575586 /DB_XREF=est:xn75g09.x1 /CLONE=IMAGE:2700352 /UG=Hs.13493 like mouse brain protein E46 /FL=gb:AL050282.1 gb:AF119662.1 gb:NM_013236.1 AW241832 ataxin 10 ATXN10 25814 NM_001167621 /// NM_013236 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 208833_s_at AF119662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119662.1 /DEF=Homo sapiens E46 protein mRNA, complete cds. /FEA=mRNA /PROD=E46 protein /DB_XREF=gi:6563249 /UG=Hs.13493 like mouse brain protein E46 /FL=gb:AL050282.1 gb:AF119662.1 gb:NM_013236.1 AF119662 ataxin 10 ATXN10 25814 NM_001167621 /// NM_013236 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 208834_x_at BC001865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001865.1 /DEF=Homo sapiens, Similar to cadherin 1, type 1, E-cadherin (epithelial), clone MGC:1151, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cadherin 1, type 1, E-cadherin(epithelial) /DB_XREF=gi:12804838 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:BC001865.1 BC001865 ribosomal protein L23a /// small nucleolar RNA, C/D box 42A RPL23A /// SNORD42A 6147 /// 26809 NM_000984 /// NR_000014 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208835_s_at AW089673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW089673 /FEA=EST /DB_XREF=gi:6047017 /DB_XREF=est:xd21h11.x1 /CLONE=IMAGE:2594469 /UG=Hs.3688 cisplatin resistance-associated overexpressed protein /FL=gb:AB034205.1 AW089673 LUC7-like 3 (S. cerevisiae) LUC7L3 51747 NM_006107 /// NM_016424 /// XM_005257448 /// XM_005257449 /// XM_005257450 /// XM_005257451 /// XM_005257452 /// XM_005257454 /// XM_005257455 /// XM_006721943 /// XR_243663 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208836_at U51478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U51478.1 /DEF=Human sodiumpotassium-transporting ATPase beta-3 subunit mRNA, complete cds. /FEA=mRNA /PROD=sodiumpotassium-transporting ATPase beta-3subunit /DB_XREF=gi:1522634 /UG=Hs.76941 ATPase, Na+K+ transporting, beta 3 polypeptide /FL=gb:U51478.1 gb:NM_001679.1 U51478 ATPase, Na+/K+ transporting, beta 3 polypeptide ATP1B3 483 NM_001679 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 208837_at BC000027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000027.1 /DEF=Homo sapiens, integral type I protein, clone MGC:1302, mRNA, complete cds. /FEA=mRNA /PROD=integral type I protein /DB_XREF=gi:12652570 /UG=Hs.179516 integral type I protein /FL=gb:BC000027.1 gb:NM_007364.1 BC000027 transmembrane emp24 protein transport domain containing 3 TMED3 23423 NM_007364 /// XM_005254263 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 208838_at AB020636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020636.1 /DEF=Homo sapiens mRNA for KIAA0829 protein, partial cds. /FEA=mRNA /GEN=KIAA0829 /PROD=KIAA0829 protein /DB_XREF=gi:4240146 /UG=Hs.184786 TBP-interacting protein /FL=gb:AL136810.1 AB020636 cullin-associated and neddylation-dissociated 1 CAND1 55832 NM_018448 0010265 // SCF complex assembly // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from electronic annotation 208839_s_at AL136810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136810.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G0222 (from clone DKFZp434G0222); complete cds. /FEA=mRNA /GEN=DKFZp434G0222 /PROD=hypothetical protein /DB_XREF=gi:12053130 /UG=Hs.184786 TBP-interacting protein /FL=gb:AL136810.1 AL136810 cullin-associated and neddylation-dissociated 1 CAND1 55832 NM_018448 0010265 // SCF complex assembly // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from electronic annotation 208840_s_at AU149503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149503 /FEA=EST /DB_XREF=gi:11011024 /DB_XREF=est:AU149503 /CLONE=NT2RM4002447 /UG=Hs.6727 Ras-GTPase activating protein SH3 domain-binding protein 2 /FL=gb:AB014560.1 AU149503 GTPase activating protein (SH3 domain) binding protein 2 G3BP2 9908 NM_012297 /// NM_203504 /// NM_203505 /// XM_005263382 /// XM_005263383 /// XM_005263384 /// XM_005263385 /// XM_005263386 0006810 // transport // inferred from electronic annotation /// 0007253 // cytoplasmic sequestering of NF-kappaB // non-traceable author statement /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208841_s_at AB014560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014560.1 /DEF=Homo sapiens mRNA for KIAA0660 protein, complete cds. /FEA=mRNA /GEN=KIAA0660 /PROD=KIAA0660 protein /DB_XREF=gi:3327133 /UG=Hs.6727 Ras-GTPase activating protein SH3 domain-binding protein 2 /FL=gb:AB014560.1 AB014560 GTPase activating protein (SH3 domain) binding protein 2 G3BP2 9908 NM_012297 /// NM_203504 /// NM_203505 /// XM_005263382 /// XM_005263383 /// XM_005263384 /// XM_005263385 /// XM_005263386 0006810 // transport // inferred from electronic annotation /// 0007253 // cytoplasmic sequestering of NF-kappaB // non-traceable author statement /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 208842_s_at W93787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W93787 /FEA=EST /DB_XREF=gi:1422930 /DB_XREF=est:zd96c09.s1 /CLONE=IMAGE:357328 /UG=Hs.6880 DKFZP434D156 protein /FL=gb:BC001408.1 W93787 golgi reassembly stacking protein 2, 55kDa GORASP2 26003 NM_001201428 /// NM_015530 /// XM_006712408 0000278 // mitotic cell cycle // traceable author statement /// 0006996 // organelle organization // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 208843_s_at BC001408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001408.1 /DEF=Homo sapiens, clone MGC:1233, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1233) /DB_XREF=gi:12655112 /UG=Hs.6880 DKFZP434D156 protein /FL=gb:BC001408.1 BC001408 golgi reassembly stacking protein 2, 55kDa GORASP2 26003 NM_001201428 /// NM_015530 /// XM_006712408 0000278 // mitotic cell cycle // traceable author statement /// 0006996 // organelle organization // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 208844_at BC002456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002456.1 /DEF=Homo sapiens, voltage-dependent anion channel 3, clone MGC:1966, mRNA, complete cds. /FEA=mRNA /PROD=voltage-dependent anion channel 3 /DB_XREF=gi:12803280 /UG=Hs.7381 voltage-dependent anion channel 3 /FL=gb:BC002456.1 gb:U90943.1 gb:AF038962.1 gb:NM_005662.1 BC002456 voltage-dependent anion channel 3 VDAC3 7419 NM_001135694 /// NM_005662 /// XM_006716394 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 208845_at BC002456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002456.1 /DEF=Homo sapiens, voltage-dependent anion channel 3, clone MGC:1966, mRNA, complete cds. /FEA=mRNA /PROD=voltage-dependent anion channel 3 /DB_XREF=gi:12803280 /UG=Hs.7381 voltage-dependent anion channel 3 /FL=gb:BC002456.1 gb:U90943.1 gb:AF038962.1 gb:NM_005662.1 BC002456 voltage-dependent anion channel 3 VDAC3 7419 NM_001135694 /// NM_005662 /// XM_006716394 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 208846_s_at U90943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90943.1 /DEF=Human voltage dependent anion channel form 3 mRNA, complete cds. /FEA=mRNA /PROD=voltage dependent anion channel form 3 /DB_XREF=gi:2735306 /UG=Hs.7381 voltage-dependent anion channel 3 /FL=gb:BC002456.1 gb:U90943.1 gb:AF038962.1 gb:NM_005662.1 U90943 voltage-dependent anion channel 3 VDAC3 7419 NM_001135694 /// NM_005662 /// XM_006716394 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 208847_s_at M29872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29872.1 /DEF=Human alcohol dehydrogenase class III (ADH5) mRNA, complete cds. /FEA=mRNA /GEN=ADH5 /DB_XREF=gi:178131 /UG=Hs.78989 alcohol dehydrogenase 5 (class III), chi polypeptide /FL=gb:NM_000671.2 gb:M29872.1 gb:M30471.1 M29872 alcohol dehydrogenase 5 (class III), chi polypeptide ADH5 128 NM_000671 0001523 // retinoid metabolic process // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006069 // ethanol oxidation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0046294 // formaldehyde catabolic process // inferred from electronic annotation /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018467 // formaldehyde dehydrogenase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051903 // S-(hydroxymethyl)glutathione dehydrogenase activity // traceable author statement 208848_at M30471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30471.1 /DEF=Human class III alcohol dehydrogenase (ADH5) chi subunit mRNA, complete cds. /FEA=mRNA /GEN=ADH5 /PROD=alcohol dehydrogenase 3 /DB_XREF=gi:178133 /UG=Hs.78989 alcohol dehydrogenase 5 (class III), chi polypeptide /FL=gb:NM_000671.2 gb:M29872.1 gb:M30471.1 M30471 alcohol dehydrogenase 5 (class III), chi polypeptide ADH5 128 NM_000671 0001523 // retinoid metabolic process // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006069 // ethanol oxidation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0046294 // formaldehyde catabolic process // inferred from electronic annotation /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018467 // formaldehyde dehydrogenase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051903 // S-(hydroxymethyl)glutathione dehydrogenase activity // traceable author statement 208849_at AF118091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118091.1 /DEF=Homo sapiens PRO2047 mRNA, complete cds. /FEA=mRNA /PROD=PRO2047 /DB_XREF=gi:6650827 /UG=Hs.284136 PRO2047 protein /FL=gb:AF118091.1 AF118091 208850_s_at AL558479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL558479 /FEA=EST /DB_XREF=gi:12903040 /DB_XREF=est:AL558479 /CLONE=CS0DJ006YK21 (5 prime) /UG=Hs.125359 Thy-1 cell surface antigen /FL=gb:BC005175.1 gb:NM_006288.1 gb:AL161958.1 AL558479 Thy-1 cell surface antigen THY1 7070 NM_006288 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // non-traceable author statement /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity 208851_s_at AL161958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL161958.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761B15121 (from clone DKFZp761B15121); complete cds. /FEA=mRNA /GEN=DKFZp761B15121 /PROD=hypothetical protein /DB_XREF=gi:7328010 /UG=Hs.125359 Thy-1 cell surface antigen /FL=gb:BC005175.1 gb:NM_006288.1 gb:AL161958.1 AL161958 Thy-1 cell surface antigen THY1 7070 NM_006288 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // non-traceable author statement /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity 208852_s_at AI761759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761759 /FEA=EST /DB_XREF=gi:5177515 /DB_XREF=est:wg67h12.x1 /CLONE=IMAGE:2370215 /UG=Hs.155560 calnexin /FL=gb:NM_001746.1 gb:BC003552.1 gb:M94859.1 gb:M98452.1 gb:L10284.1 gb:L18887.1 AI761759 calnexin CANX 821 NM_001024649 /// NM_001746 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0072583 // clathrin-mediated endocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 208853_s_at L18887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L18887.1 /DEF=Human calnexin mRNA, complete cds. /FEA=mRNA /PROD=calnexin /DB_XREF=gi:306480 /UG=Hs.155560 calnexin /FL=gb:NM_001746.1 gb:BC003552.1 gb:M94859.1 gb:M98452.1 gb:L10284.1 gb:L18887.1 L18887 calnexin CANX 821 NM_001024649 /// NM_001746 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0072583 // clathrin-mediated endocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 208854_s_at AA586774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA586774 /FEA=EST /DB_XREF=gi:2397588 /DB_XREF=est:nn75a04.s1 /CLONE=IMAGE:1089678 /UG=Hs.168913 serinethreonine kinase 24 (Ste20, yeast homolog) /FL=gb:AF083420.1 AA586774 serine/threonine kinase 24 STK24 8428 NM_001032296 /// NM_001286649 /// NM_003576 /// XM_005254078 /// XM_005254079 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048679 // regulation of axon regeneration // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208855_s_at AF083420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083420.1 /DEF=Homo sapiens brain-specific STE20-like protein kinase 3 (STK3) mRNA, complete cds. /FEA=mRNA /GEN=STK3 /PROD=brain-specific STE20-like protein kinase 3 /DB_XREF=gi:5326765 /UG=Hs.168913 serinethreonine kinase 24 (Ste20, yeast homolog) /FL=gb:AF083420.1 AF083420 serine/threonine kinase 24 STK24 8428 NM_001032296 /// NM_001286649 /// NM_003576 /// XM_005254078 /// XM_005254079 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048679 // regulation of axon regeneration // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208856_x_at BC003655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003655.1 /DEF=Homo sapiens, ribosomal protein, large, P0, clone MGC:4770, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein, large, P0 /DB_XREF=gi:13177771 /UG=Hs.73742 ribosomal protein, large, P0 /FL=gb:BC000087.1 gb:BC003655.1 BC003655 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208857_s_at M93008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M93008.1 /DEF=Human L-isoaspartylD-aspartyl protein carboxyl methyltransferase isozyme II mRNA, complete cds. /FEA=mRNA /PROD=L-isoaspartylD-aspartyl protein carboxylmethyltransferase /DB_XREF=gi:180636 /UG=Hs.79137 protein-L-isoaspartate (D-aspartate) O-methyltransferase /FL=gb:D25546.1 gb:M93008.1 gb:D13892.1 M93008 protein-L-isoaspartate (D-aspartate) O-methyltransferase PCMT1 5110 NM_001252049 /// NM_001252050 /// NM_001252051 /// NM_001252052 /// NM_001252053 /// NM_005389 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006479 // protein methylation // traceable author statement /// 0030091 // protein repair // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 208858_s_at BC004998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004998.1 /DEF=Homo sapiens, Similar to membrane bound C2 domain containing protein, clone MGC:4422, mRNA, complete cds. /FEA=mRNA /PROD=Similar to membrane bound C2 domain containingprotein /DB_XREF=gi:13436457 /UG=Hs.8309 KIAA0747 protein /FL=gb:BC004998.1 BC004998 extended synaptotagmin-like protein 1 ESYT1 23344 NM_001184796 /// NM_015292 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208859_s_at AI650257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI650257 /FEA=EST /DB_XREF=gi:4734236 /DB_XREF=est:wa17f11.x1 /CLONE=IMAGE:2298381 /UG=Hs.96264 alpha thalassemiamental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog) /FL=gb:U09820.1 gb:NM_000489.1 gb:U72937.2 AI650257 alpha thalassemia/mental retardation syndrome X-linked ATRX 546 NM_000489 /// NM_138270 /// NM_138271 /// XM_005262153 /// XM_005262154 /// XM_005262155 /// XM_005262156 /// XM_005262157 /// XM_006724666 /// XM_006724667 /// XM_006724668 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from sequence or structural similarity /// 0032206 // positive regulation of telomere maintenance // inferred from sequence or structural similarity /// 0032508 // DNA duplex unwinding // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072711 // cellular response to hydroxyurea // inferred from sequence or structural similarity /// 1901581 // negative regulation of telomeric RNA transcription from RNA pol II promoter // inferred from sequence or structural similarity 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0031933 // telomeric heterochromatin // inferred from sequence or structural similarity /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 208860_s_at U09820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U09820.1 /DEF=Human helicase II (RAD54L) mRNA, complete cds. /FEA=mRNA /GEN=RAD54L /PROD=helicase II /DB_XREF=gi:606832 /UG=Hs.96264 alpha thalassemiamental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog) /FL=gb:U09820.1 gb:NM_000489.1 gb:U72937.2 U09820 alpha thalassemia/mental retardation syndrome X-linked ATRX 546 NM_000489 /// NM_138270 /// NM_138271 /// XM_005262153 /// XM_005262154 /// XM_005262155 /// XM_005262156 /// XM_005262157 /// XM_006724666 /// XM_006724667 /// XM_006724668 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from sequence or structural similarity /// 0032206 // positive regulation of telomere maintenance // inferred from sequence or structural similarity /// 0032508 // DNA duplex unwinding // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072711 // cellular response to hydroxyurea // inferred from sequence or structural similarity /// 1901581 // negative regulation of telomeric RNA transcription from RNA pol II promoter // inferred from sequence or structural similarity 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0031933 // telomeric heterochromatin // inferred from sequence or structural similarity /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 208861_s_at U72937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U72937.2 /DEF=Homo sapiens putative DNA dependent ATPase and helicase (ATRX) mRNA, alternatively spliced product 2, complete cds. /FEA=mRNA /GEN=ATRX /PROD=putative DNA dependent ATPase and helicase /DB_XREF=gi:6960325 /UG=Hs.96264 alpha thalassemiamental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog) /FL=gb:U09820.1 gb:NM_000489.1 gb:U72937.2 U72937 alpha thalassemia/mental retardation syndrome X-linked ATRX 546 NM_000489 /// NM_138270 /// NM_138271 /// XM_005262153 /// XM_005262154 /// XM_005262155 /// XM_005262156 /// XM_005262157 /// XM_006724666 /// XM_006724667 /// XM_006724668 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from sequence or structural similarity /// 0032206 // positive regulation of telomere maintenance // inferred from sequence or structural similarity /// 0032508 // DNA duplex unwinding // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072711 // cellular response to hydroxyurea // inferred from sequence or structural similarity /// 1901581 // negative regulation of telomeric RNA transcription from RNA pol II promoter // inferred from sequence or structural similarity 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0031933 // telomeric heterochromatin // inferred from sequence or structural similarity /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 208862_s_at AW073672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW073672 /FEA=EST /DB_XREF=gi:6028670 /DB_XREF=est:xb01b04.x1 /CLONE=IMAGE:2574991 /UG=Hs.166011 catenin (cadherin-associated protein), delta 1 /FL=gb:AF062328.1 AW073672 catenin (cadherin-associated protein), delta 1 /// TMX2-CTNND1 readthrough (NMD candidate) CTNND1 /// TMX2-CTNND1 1500 /// 100528016 NM_001085458 /// NM_001085459 /// NM_001085460 /// NM_001085461 /// NM_001085462 /// NM_001085463 /// NM_001085464 /// NM_001085465 /// NM_001085466 /// NM_001085467 /// NM_001085468 /// NM_001085469 /// NM_001206883 /// NM_001206884 /// NM_001206885 /// NM_001206886 /// NM_001206887 /// NM_001206888 /// NM_001206889 /// NM_001206890 /// NM_001206891 /// NM_001331 /// NR_037646 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0060690 // epithelial cell differentiation involved in salivary gland development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 208863_s_at M72709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M72709.1 /DEF=Human alternative splicing factor mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:179073 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M72709.1 M72709 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 208864_s_at AF313911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF313911.1 /DEF=Homo sapiens thioredoxin mRNA, complete cds. /FEA=mRNA /PROD=thioredoxin /DB_XREF=gi:11345419 /UG=Hs.76136 thioredoxin /FL=gb:AF313911.1 gb:BC003377.1 gb:J04026.1 gb:NM_003329.1 gb:AF276919.1 gb:AY004872.1 AF313911 thioredoxin TXN 7295 NM_001244938 /// NM_003329 /// XM_006717276 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016999 // antibiotic metabolic process // inferred from electronic annotation /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071548 // response to dexamethasone // inferred from electronic annotation /// 0097068 // response to thyroxine // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015037 // peptide disulfide oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208865_at BG534245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG534245 /FEA=EST /DB_XREF=gi:13525785 /DB_XREF=est:602553366F1 /CLONE=IMAGE:4662880 /UG=Hs.144477 hypothetical protein PRO2975 /FL=gb:AF119911.1 BG534245 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208866_at BF510713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF510713 /FEA=EST /DB_XREF=gi:11594011 /DB_XREF=est:UI-H-BI4-aoh-b-03-0-UI.s1 /CLONE=IMAGE:3084629 /UG=Hs.144477 hypothetical protein PRO2975 /FL=gb:AF119911.1 BF510713 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208867_s_at AF119911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119911.1 /DEF=Homo sapiens PRO2975 mRNA, complete cds. /FEA=mRNA /PROD=PRO2975 /DB_XREF=gi:7770258 /UG=Hs.144477 hypothetical protein PRO2975 /FL=gb:AF119911.1 AF119911 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 208868_s_at BF125756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF125756 /FEA=EST /DB_XREF=gi:10964796 /DB_XREF=est:601763146F1 /CLONE=IMAGE:4026010 /UG=Hs.282654 Homo sapiens mRNA; cDNA DKFZp564N1272 (from clone DKFZp564N1272); complete cds /FL=gb:AL136676.1 gb:AF087847.1 BF125756 GABA(A) receptor-associated protein like 1 GABARAPL1 23710 NM_031412 /// XM_005253344 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0012501 // programmed cell death // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // not recorded /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 208869_s_at AF087847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF087847.1 /DEF=Homo sapiens GABA-A receptor-associated protein like 1 (GABARAPL1) mRNA, complete cds. /FEA=mRNA /GEN=GABARAPL1 /PROD=GABA-A receptor-associated protein like 1 /DB_XREF=gi:13375570 /UG=Hs.282654 Homo sapiens mRNA; cDNA DKFZp564N1272 (from clone DKFZp564N1272); complete cds /FL=gb:AL136676.1 gb:AF087847.1 AF087847 GABA(A) receptor-associated protein like 1 GABARAPL1 23710 NM_031412 /// XM_005253344 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0012501 // programmed cell death // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // not recorded /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 208870_x_at BC000931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000931.2 /DEF=Homo sapiens, ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1, clone MGC:5380, mRNA, complete cds. /FEA=mRNA /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, gamma polypeptide 1 /DB_XREF=gi:13111822 /UG=Hs.155433 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 /FL=gb:BC000470.1 gb:BC000931.2 gb:D16562.1 BC000931 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 ATP5C1 509 NM_001001973 /// NM_005174 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred by curator /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 208871_at D31840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D31840.1 /DEF=Human DRPLA mRNA for ORF, complete cds. /FEA=mRNA /GEN=DRPLA /DB_XREF=gi:862329 /UG=Hs.169488 dentatorubral-pallidoluysian atrophy (atrophin-1) /FL=gb:D38529.1 gb:NM_001940.2 gb:D31840.1 gb:U23851.1 D31840 atrophin 1 ATN1 1822 NM_001007026 /// NM_001940 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0050827 // toxin receptor binding // inferred from electronic annotation 208872_s_at AA814140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA814140 /FEA=EST /DB_XREF=gi:2883736 /DB_XREF=est:ob25c08.s1 /CLONE=IMAGE:1324718 /UG=Hs.178112 DNA segment, single copy probe LNS-CAILNS-CAII (deleted in polyposis /FL=gb:BC000232.1 AA814140 receptor accessory protein 5 REEP5 7905 NM_005669 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208873_s_at BC000232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000232.1 /DEF=Homo sapiens, Similar to deleted in polyposis 1, clone MGC:2267, mRNA, complete cds. /FEA=mRNA /PROD=Similar to deleted in polyposis 1 /DB_XREF=gi:12652946 /UG=Hs.178112 DNA segment, single copy probe LNS-CAILNS-CAII (deleted in polyposis /FL=gb:BC000232.1 BC000232 receptor accessory protein 5 REEP5 7905 NM_005669 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208874_x_at BC002545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002545.1 /DEF=Homo sapiens, protein phosphatase 2A, regulatory subunit B (PR 53), clone MGC:2184, mRNA, complete cds. /FEA=mRNA /PROD=protein phosphatase 2A, regulatory subunit B(PR 53) /DB_XREF=gi:12803442 /UG=Hs.236963 protein phosphatase 2A, regulatory subunit B (PR 53) /FL=gb:BC002545.1 BC002545 protein phosphatase 2A activator, regulatory subunit 4 PPP2R4 5524 NM_001193397 /// NM_001271832 /// NM_021131 /// NM_178000 /// NM_178001 /// NM_178002 /// NM_178003 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0030472 // mitotic spindle organization in nucleus // not recorded /// 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008160 // protein tyrosine phosphatase activator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019211 // phosphatase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 208875_s_at BF796470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF796470 /FEA=EST /DB_XREF=gi:12101524 /DB_XREF=est:602259926F1 /CLONE=IMAGE:4342999 /UG=Hs.284275 Homo sapiens PAK2 mRNA, complete cds /FL=gb:AF092132.1 BF796470 p21 protein (Cdc42/Rac)-activated kinase 2 PAK2 5062 NM_002577 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 208876_s_at AI076186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI076186 /FEA=EST /DB_XREF=gi:3405364 /DB_XREF=est:oz01g01.x1 /CLONE=IMAGE:1674096 /UG=Hs.284275 Homo sapiens PAK2 mRNA, complete cds /FL=gb:AF092132.1 AI076186 p21 protein (Cdc42/Rac)-activated kinase 2 PAK2 5062 NM_002577 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 208877_at W74494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W74494 /FEA=EST /DB_XREF=gi:1384781 /DB_XREF=est:zd75f10.s1 /CLONE=IMAGE:346507 /UG=Hs.284275 Homo sapiens PAK2 mRNA, complete cds /FL=gb:AF092132.1 W74494 p21 protein (Cdc42/Rac)-activated kinase 2 PAK2 5062 NM_002577 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 208878_s_at AF092132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF092132.1 /DEF=Homo sapiens PAK2 mRNA, complete cds. /FEA=mRNA /PROD=PAK2 /DB_XREF=gi:5138913 /UG=Hs.284275 Homo sapiens PAK2 mRNA, complete cds /FL=gb:AF092132.1 AF092132 p21 protein (Cdc42/Rac)-activated kinase 2 PAK2 5062 NM_002577 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 208879_x_at BG469030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG469030 /FEA=EST /DB_XREF=gi:13401215 /DB_XREF=est:602510773F1 /CLONE=IMAGE:4644787 /UG=Hs.31334 putative mitochondrial outer membrane protein import receptor /FL=gb:BC001666.1 gb:AF026031.1 gb:AB019219.1 gb:NM_012469.1 gb:AF221842.1 BG469030 pre-mRNA processing factor 6 PRPF6 24148 NM_012469 /// XM_006723769 0000244 // spliceosomal tri-snRNP complex assembly // inferred by curator /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006403 // RNA localization // inferred from mutant phenotype /// 0008380 // RNA splicing // non-traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071001 // U4/U6 snRNP // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003713 // transcription coactivator activity // inferred from genetic interaction /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from physical interaction 208880_s_at AB019219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB019219.1 /DEF=Homo sapiens mRNA, complete cds, similar to yeast pre-mRNA splicing factors, Prp1Zer1 and Prp6. /FEA=mRNA /DB_XREF=gi:4164165 /UG=Hs.31334 putative mitochondrial outer membrane protein import receptor /FL=gb:BC001666.1 gb:AF026031.1 gb:AB019219.1 gb:NM_012469.1 gb:AF221842.1 AB019219 pre-mRNA processing factor 6 PRPF6 24148 NM_012469 /// XM_006723769 0000244 // spliceosomal tri-snRNP complex assembly // inferred by curator /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006403 // RNA localization // inferred from mutant phenotype /// 0008380 // RNA splicing // non-traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071001 // U4/U6 snRNP // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003713 // transcription coactivator activity // inferred from genetic interaction /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from physical interaction 208881_x_at BC005247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005247.1 /DEF=Homo sapiens, isopentenyl-diphosphate delta isomerase, clone MGC:12281, mRNA, complete cds. /FEA=mRNA /PROD=isopentenyl-diphosphate delta isomerase /DB_XREF=gi:13528899 /UG=Hs.76038 isopentenyl-diphosphate delta isomerase /FL=gb:BC005247.1 BC005247 isopentenyl-diphosphate delta isomerase 1 IDI1 3422 NM_004508 /// XM_005252445 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050992 // dimethylallyl diphosphate biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from direct assay /// 0004452 // isopentenyl-diphosphate delta-isomerase activity // inferred from direct assay /// 0004452 // isopentenyl-diphosphate delta-isomerase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208882_s_at U69567 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U69567 /FEA=EST /DB_XREF=gi:2731398 /DB_XREF=est:U69567 /CLONE=c-2mell /UG=Hs.278428 progestin induced protein /FL=gb:NM_015902.2 gb:AF006010.1 gb:U95000.1 U69567 ubiquitin protein ligase E3 component n-recognin 5 UBR5 51366 NM_001282873 /// NM_015902 /// XM_005250956 /// XM_005250957 /// XM_005250959 /// XM_005250960 /// XM_005250962 /// XR_242392 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208883_at BF515424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF515424 /FEA=EST /DB_XREF=gi:11600603 /DB_XREF=est:UI-H-BW1-anm-h-09-0-UI.s1 /CLONE=IMAGE:3082985 /UG=Hs.278428 progestin induced protein /FL=gb:NM_015902.2 gb:AF006010.1 gb:U95000.1 BF515424 ubiquitin protein ligase E3 component n-recognin 5 UBR5 51366 NM_001282873 /// NM_015902 /// XM_005250956 /// XM_005250957 /// XM_005250959 /// XM_005250960 /// XM_005250962 /// XR_242392 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208884_s_at AF006010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006010.1 /DEF=Homo sapiens progestin induced protein (EDD) mRNA, complete cds. /FEA=mRNA /GEN=EDD /PROD=progestin induced protein /DB_XREF=gi:4101694 /UG=Hs.278428 progestin induced protein /FL=gb:NM_015902.2 gb:AF006010.1 gb:U95000.1 AF006010 ubiquitin protein ligase E3 component n-recognin 5 UBR5 51366 NM_001282873 /// NM_015902 /// XM_005250956 /// XM_005250957 /// XM_005250959 /// XM_005250960 /// XM_005250962 /// XR_242392 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208885_at J02923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02923.1 /DEF=Human 65-kilodalton phosphoprotein (p65) mRNA, complete cds. /FEA=mRNA /PROD=phosphoprotein p65 /DB_XREF=gi:189501 /UG=Hs.76506 lymphocyte cytosolic protein 1 (L-plastin) /FL=gb:J02923.1 gb:M22300.1 gb:NM_002298.2 J02923 lymphocyte cytosolic protein 1 (L-plastin) LCP1 3936 NM_002298 /// XM_005266374 0002286 // T cell activation involved in immune response // inferred from direct assay /// 0010737 // protein kinase A signaling // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033157 // regulation of intracellular protein transport // inferred from direct assay /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from mutant phenotype /// 0001726 // ruffle // inferred from mutant phenotype /// 0001891 // phagocytic cup // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from mutant phenotype /// 0032432 // actin filament bundle // inferred from mutant phenotype /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from mutant phenotype 208886_at BC000145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000145.1 /DEF=Homo sapiens, H1 histone family, member 0, clone MGC:5241, mRNA, complete cds. /FEA=mRNA /PROD=H1 histone family, member 0 /DB_XREF=gi:12652786 /UG=Hs.226117 H1 histone family, member 0 /FL=gb:BC000145.1 gb:NM_005318.1 BC000145 H1 histone family, member 0 H1F0 3005 NM_005318 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208887_at BC000733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000733.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD), clone MGC:2053, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 3,subunit 4 (delta, 44kD) /DB_XREF=gi:12653882 /UG=Hs.28081 eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD) /FL=gb:AF094850.1 gb:BC000733.1 gb:AF020833.1 gb:U96074.1 gb:NM_003755.1 BC000733 eukaryotic translation initiation factor 3, subunit G EIF3G 8666 NM_003755 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208888_s_at AI499095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI499095 /FEA=EST /DB_XREF=gi:4391077 /DB_XREF=est:to04f05.x1 /CLONE=IMAGE:2178081 /UG=Hs.287994 nuclear receptor co-repressor 2 /FL=gb:AF125672.1 AI499095 nuclear receptor corepressor 2 NCOR2 9612 NM_001077261 /// NM_001206654 /// NM_006312 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0072365 // regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 208889_s_at AI373205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI373205 /FEA=EST /DB_XREF=gi:4153071 /DB_XREF=est:qz13h02.x1 /CLONE=IMAGE:2021427 /UG=Hs.287994 nuclear receptor co-repressor 2 /FL=gb:AF125672.1 AI373205 nuclear receptor corepressor 2 NCOR2 9612 NM_001077261 /// NM_001206654 /// NM_006312 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0072365 // regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 208890_s_at BC004542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004542.1 /DEF=Homo sapiens, clone MGC:11315, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11315) /DB_XREF=gi:13528689 /UG=Hs.3989 plexin B2 /FL=gb:BC004542.1 BC004542 plexin B2 PLXNB2 23654 NM_012401 /// XM_005261908 /// XM_005261909 /// XM_005261910 /// XM_005261911 /// XM_006724413 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 2001222 // regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity 208891_at BC003143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003143.1 /DEF=Homo sapiens, dual specificity phosphatase 6, clone MGC:3789, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 6 /DB_XREF=gi:13111942 /UG=Hs.180383 dual specificity phosphatase 6 /FL=gb:BC003562.1 gb:BC003143.1 gb:BC005047.1 gb:AB013382.1 gb:NM_001946.1 BC003143 dual specificity phosphatase 6 DUSP6 1848 NM_001946 /// NM_022652 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0042663 // regulation of endodermal cell fate specification // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051409 // response to nitrosative stress // inferred from expression pattern /// 0060420 // regulation of heart growth // not recorded /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay 208892_s_at BC003143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003143.1 /DEF=Homo sapiens, dual specificity phosphatase 6, clone MGC:3789, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 6 /DB_XREF=gi:13111942 /UG=Hs.180383 dual specificity phosphatase 6 /FL=gb:BC003562.1 gb:BC003143.1 gb:BC005047.1 gb:AB013382.1 gb:NM_001946.1 BC003143 dual specificity phosphatase 6 DUSP6 1848 NM_001946 /// NM_022652 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0042663 // regulation of endodermal cell fate specification // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051409 // response to nitrosative stress // inferred from expression pattern /// 0060420 // regulation of heart growth // not recorded /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay 208893_s_at BC005047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005047.1 /DEF=Homo sapiens, clone MGC:12852, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12852) /DB_XREF=gi:13477170 /UG=Hs.180383 dual specificity phosphatase 6 /FL=gb:BC003562.1 gb:BC003143.1 gb:BC005047.1 gb:AB013382.1 gb:NM_001946.1 BC005047 dual specificity phosphatase 6 DUSP6 1848 NM_001946 /// NM_022652 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0042663 // regulation of endodermal cell fate specification // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051409 // response to nitrosative stress // inferred from expression pattern /// 0060420 // regulation of heart growth // not recorded /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay 208894_at M60334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60334.1 /DEF=Human MHC class II HLA-DR-alpha mRNA, complete cds. /FEA=mRNA /GEN=HLA-DRA /PROD=cell surface glycoprotein /DB_XREF=gi:188255 /UG=Hs.76807 major histocompatibility complex, class II, DR alpha /FL=gb:M60334.1 gb:NM_019111.1 M60334 major histocompatibility complex, class II, DR alpha HLA-DRA 3122 NM_019111 0002376 // immune system process // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 208895_s_at BG530850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG530850 /FEA=EST /DB_XREF=gi:13522387 /DB_XREF=est:602559887F1 /CLONE=IMAGE:4698044 /UG=Hs.100555 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated) /FL=gb:BC001238.1 gb:BC003360.1 BG530850 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DDX18 8886 NM_006773 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208896_at X98743 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X98743.1 /DEF=H.sapiens mRNA for RNA helicase (Myc-regulated dead box protein). /FEA=mRNA /PROD=RNA helicase /DB_XREF=gi:1498228 /UG=Hs.100555 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated) /FL=gb:BC001238.1 gb:BC003360.1 X98743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DDX18 8886 NM_006773 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208897_s_at BC003360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003360.1 /DEF=Homo sapiens, DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated), clone MGC:5316, mRNA, complete cds. /FEA=mRNA /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18(Myc-regulated) /DB_XREF=gi:13097182 /UG=Hs.100555 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 18 (Myc-regulated) /FL=gb:BC001238.1 gb:BC003360.1 BC003360 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DDX18 8886 NM_006773 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208898_at AF077614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077614.1 /DEF=Homo sapiens vacuolar ATP synthase subunit D homolog (VATD) mRNA, complete cds. /FEA=mRNA /GEN=VATD /PROD=vacuolar ATP synthase subunit D homolog /DB_XREF=gi:11999089 /UG=Hs.272630 vacuolar proton pump delta polypeptide /FL=gb:AF104629.1 gb:AF077614.1 gb:BC001411.1 gb:AF145316.1 gb:AF100741.1 gb:NM_015994.1 AF077614 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D ATP6V1D 51382 NM_015994 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0061512 // protein localization to cilium // inferred from mutant phenotype /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208899_x_at AF100741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100741.1 /DEF=Homo sapiens vacuolar H-ATPase subunit D mRNA, complete cds. /FEA=mRNA /PROD=vacuolar H-ATPase subunit D /DB_XREF=gi:5138992 /UG=Hs.272630 vacuolar proton pump delta polypeptide /FL=gb:AF104629.1 gb:AF077614.1 gb:BC001411.1 gb:AF145316.1 gb:AF100741.1 gb:NM_015994.1 AF100741 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D ATP6V1D 51382 NM_015994 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0061512 // protein localization to cilium // inferred from mutant phenotype /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208900_s_at AW025108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW025108 /FEA=EST /DB_XREF=gi:5878638 /DB_XREF=est:wu71f09.x1 /CLONE=IMAGE:2525513 /UG=Hs.317 topoisomerase (DNA) I /FL=gb:NM_003286.1 gb:J03250.1 AW025108 topoisomerase (DNA) I TOP1 7150 NM_003286 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // not recorded /// 0006265 // DNA topological change // not recorded /// 0006265 // DNA topological change // inferred from direct assay /// 0006338 // chromatin remodeling // not recorded /// 0007059 // chromosome segregation // not recorded /// 0012501 // programmed cell death // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern 0000228 // nuclear chromosome // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031298 // replication fork protection complex // not recorded /// 0043204 // perikaryon // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003917 // DNA topoisomerase type I activity // inferred from direct assay /// 0003917 // DNA topoisomerase type I activity // inferred from mutant phenotype /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208901_s_at J03250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03250.1 /DEF=Human topoisomerase I mRNA, complete cds. /FEA=mRNA /GEN=TOP1 /DB_XREF=gi:339805 /UG=Hs.317 topoisomerase (DNA) I /FL=gb:NM_003286.1 gb:J03250.1 J03250 topoisomerase (DNA) I TOP1 7150 NM_003286 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // not recorded /// 0006265 // DNA topological change // not recorded /// 0006265 // DNA topological change // inferred from direct assay /// 0006338 // chromatin remodeling // not recorded /// 0007059 // chromosome segregation // not recorded /// 0012501 // programmed cell death // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern 0000228 // nuclear chromosome // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031298 // replication fork protection complex // not recorded /// 0043204 // perikaryon // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003917 // DNA topoisomerase type I activity // inferred from direct assay /// 0003917 // DNA topoisomerase type I activity // inferred from mutant phenotype /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208902_s_at BF431363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431363 /FEA=EST /DB_XREF=gi:11443477 /DB_XREF=est:7o12c03.x1 /CLONE=IMAGE:3573869 /UG=Hs.153177 ribosomal protein S28 /FL=gb:BC000354.1 BF431363 ribosomal protein S28 RPS28 6234 NM_001031 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208903_at BF431363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431363 /FEA=EST /DB_XREF=gi:11443477 /DB_XREF=est:7o12c03.x1 /CLONE=IMAGE:3573869 /UG=Hs.153177 ribosomal protein S28 /FL=gb:BC000354.1 BF431363 ribosomal protein S28 RPS28 6234 NM_001031 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208904_s_at BC000354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000354.1 /DEF=Homo sapiens, ribosomal protein S28, clone MGC:8658, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S28 /DB_XREF=gi:12653172 /UG=Hs.153177 ribosomal protein S28 /FL=gb:BC000354.1 BC000354 ribosomal protein S28 RPS28 6234 NM_001031 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208905_at BC005299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005299.1 /DEF=Homo sapiens, cytochrome c, clone MGC:12367, mRNA, complete cds. /FEA=mRNA /PROD=cytochrome c /DB_XREF=gi:13529022 /UG=Hs.169248 cytochrome c /FL=gb:NM_018947.1 gb:BC005299.1 BC005299 cytochrome c, somatic CYCS 54205 NM_018947 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0070469 // respiratory chain // inferred from electronic annotation 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // traceable author statement /// 0045155 // electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208906_at BC004911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004911.1 /DEF=Homo sapiens, Similar to G protein gamma 3 linked gene, clone MGC:4694, mRNA, complete cds. /FEA=mRNA /PROD=Similar to G protein gamma 3 linked gene /DB_XREF=gi:13436205 /UG=Hs.21970 guanine nucleotide binding protein (G protein), gamma 3, linked /FL=gb:BC004911.1 BC004911 Berardinelli-Seip congenital lipodystrophy 2 (seipin) /// HNRNPUL2-BSCL2 readthrough BSCL2 /// HNRNPUL2-BSCL2 26580 /// 100534595 NM_001122955 /// NM_001130702 /// NM_032667 /// NR_037946 /// NR_037948 /// NR_037949 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019915 // lipid storage // inferred from mutant phenotype /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0050995 // negative regulation of lipid catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208907_s_at BC005373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005373.1 /DEF=Homo sapiens, PTD017 protein, clone MGC:12489, mRNA, complete cds. /FEA=mRNA /PROD=PTD017 protein /DB_XREF=gi:13529220 /UG=Hs.274417 PTD017 protein /FL=gb:BC005373.1 gb:AF100761.1 gb:AF151017.1 gb:NM_014046.1 BC005373 mitochondrial ribosomal protein S18B MRPS18B 28973 NM_014046 /// XM_005249030 /// XM_005272798 /// XM_005274944 /// XM_005275098 /// XM_005275236 /// XM_005275374 /// XM_005275534 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 208908_s_at AF327443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF327443.1 /DEF=Homo sapiens calpastatin mRNA, complete cds. /FEA=mRNA /PROD=calpastatin /DB_XREF=gi:12056961 /UG=Hs.279607 calpastatin /FL=gb:AF327443.1 gb:U26724.2 AF327443 calpastatin CAST 831 NM_001042440 /// NM_001042441 /// NM_001042442 /// NM_001042443 /// NM_001042444 /// NM_001042445 /// NM_001042446 /// NM_001190442 /// NM_001284212 /// NM_001284213 /// NM_001750 /// NM_173060 /// NM_173061 /// NM_173062 /// NM_173063 /// NR_033798 /// NR_104285 /// XM_006714696 /// XM_006714697 /// XM_006714698 /// XM_006714699 /// XM_006714700 /// XM_006714701 /// XM_006714702 /// XM_006714703 /// XM_006714704 /// XM_006714705 /// XM_006714706 /// XM_006714707 /// XM_006714708 /// XM_006714709 /// XM_006714710 /// XM_006714711 /// XM_006714712 /// XM_006714713 /// XM_006714714 /// XM_006714715 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010859 // calcium-dependent cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208909_at BC000649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000649.1 /DEF=Homo sapiens, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1, clone MGC:1362, mRNA, complete cds. /FEA=mRNA /PROD=ubiquinol-cytochrome c reductase, Rieskeiron-sulfur polypeptide 1 /DB_XREF=gi:12653726 /UG=Hs.3712 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 /FL=gb:BC000649.1 gb:NM_006003.1 BC000649 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 UQCRFS1 7386 NM_006003 0009725 // response to hormone // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016679 // oxidoreductase activity, acting on diphenols and related substances as donors // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 208910_s_at L04636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L04636.1 /DEF=Homo sapiens pre-mRNA splicing factor 2 p32 subunit (SF2p32) mRNA, complete cds. /FEA=mRNA /PROD=splicing factor /DB_XREF=gi:338044 /UG=Hs.78614 complement component 1, q subcomponent binding protein /FL=gb:NM_001212.2 gb:BC000435.1 gb:L04636.1 L04636 complement component 1, q subcomponent binding protein C1QBP 708 NM_001212 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0039534 // negative regulation of MDA-5 signaling pathway // inferred from direct assay /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070131 // positive regulation of mitochondrial translation // inferred from sequence or structural similarity /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from direct assay /// 0030984 // kininogen binding // inferred from direct assay /// 0031690 // adrenergic receptor binding // inferred from sequence or structural similarity /// 0097177 // mitochondrial ribosome binding // inferred from sequence or structural similarity 208911_s_at M34055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34055.1 /DEF=Human pyruvate dehydrogenase E1-beta subunit mRNA, complete cds. /FEA=mRNA /GEN=PDHB /DB_XREF=gi:190791 /UG=Hs.979 pyruvate dehydrogenase (lipoamide) beta /FL=gb:BC000439.1 gb:BC001924.1 gb:J03576.1 gb:M34479.1 gb:M54788.1 gb:M34055.1 gb:NM_000925.1 M34055 pyruvate dehydrogenase (lipoamide) beta PDHB 5162 NM_000925 /// NM_001173468 /// NR_033384 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation 208912_s_at BC001362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001362.1 /DEF=Homo sapiens, 2,3-cyclic nucleotide 3 phosphodiesterase, clone MGC:2262, mRNA, complete cds. /FEA=mRNA /PROD=2,3-cyclic nucleotide 3 phosphodiesterase /DB_XREF=gi:12655028 /UG=Hs.150741 2,3-cyclic nucleotide 3 phosphodiesterase /FL=gb:BC001362.1 gb:M19650.1 BC001362 2',3'-cyclic nucleotide 3' phosphodiesterase CNP 1267 NM_033133 /// XM_006721701 /// XM_006721702 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009214 // cyclic nucleotide catabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030900 // forebrain development // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004113 // 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030551 // cyclic nucleotide binding // inferred from electronic annotation 208913_at AA868560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA868560 /FEA=EST /DB_XREF=gi:2964005 /DB_XREF=est:ak43g11.s1 /CLONE=IMAGE:1408772 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 /FL=gb:AF190863.1 gb:AF233522.1 gb:AF165531.1 gb:NM_015044.1 AA868560 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 208914_at BE646414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646414 /FEA=EST /DB_XREF=gi:9970725 /DB_XREF=est:7e86d08.x1 /CLONE=IMAGE:3292047 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 /FL=gb:AF190863.1 gb:AF233522.1 gb:AF165531.1 gb:NM_015044.1 BE646414 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 208915_s_at AF190863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF190863.1 /DEF=Homo sapiens ADP-ribosylation factor binding protein GGA2 (GGA2) mRNA, complete cds. /FEA=mRNA /GEN=GGA2 /PROD=ADP-ribosylation factor binding protein GGA2 /DB_XREF=gi:6179913 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 /FL=gb:AF190863.1 gb:AF233522.1 gb:AF165531.1 gb:NM_015044.1 AF190863 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 208916_at AF105230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF105230.1 /DEF=Homo sapiens neutral amino acid transporter (SLC1A5) mRNA, complete cds. /FEA=mRNA /GEN=SLC1A5 /PROD=neutral amino acid transporter /DB_XREF=gi:4191561 /UG=Hs.183556 solute carrier family 1 (neutral amino acid transporter), member 5 /FL=gb:BC000062.1 gb:U53347.1 gb:AF102826.1 gb:AF105230.1 gb:AF105423.1 gb:NM_005628.1 AF105230 solute carrier family 1 (neutral amino acid transporter), member 5 SLC1A5 6510 NM_001145144 /// NM_001145145 /// NM_005628 /// XM_005259167 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0006860 // extracellular amino acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0015804 // neutral amino acid transport // traceable author statement /// 0015825 // L-serine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015186 // L-glutamine transmembrane transporter activity // traceable author statement /// 0015194 // L-serine transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 208917_x_at BE674658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674658 /FEA=EST /DB_XREF=gi:10035280 /DB_XREF=est:7e93f05.x1 /CLONE=IMAGE:3292737 /UG=Hs.220324 hypothetical protein FLJ13052 /FL=gb:BC001709.1 BE674658 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208918_s_at AI334128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI334128 /FEA=EST /DB_XREF=gi:4070687 /DB_XREF=est:qq07e12.x1 /CLONE=IMAGE:1931854 /UG=Hs.220324 hypothetical protein FLJ13052 /FL=gb:BC001709.1 AI334128 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208919_s_at BC001709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001709.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ13052, clone MGC:1900, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ13052 /DB_XREF=gi:12804578 /UG=Hs.220324 hypothetical protein FLJ13052 /FL=gb:BC001709.1 BC001709 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208920_at AV752215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV752215 /FEA=EST /DB_XREF=gi:10910063 /DB_XREF=est:AV752215 /CLONE=NPDAYH02 /UG=Hs.300741 sorcin /FL=gb:M32886.1 gb:NM_003130.1 gb:L12387.1 AV752215 sorcin SRI 6717 NM_001256891 /// NM_001256892 /// NM_003130 /// NM_198901 /// XM_006716097 0001508 // action potential // traceable author statement /// 0006508 // proteolysis // not recorded /// 0006810 // transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006880 // intracellular sequestering of iron ion // traceable author statement /// 0006942 // regulation of striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from mutant phenotype /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from mutant phenotype /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0086004 // regulation of cardiac muscle cell contraction // inferred from mutant phenotype /// 1901077 // regulation of relaxation of muscle // inferred from mutant phenotype /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from mutant phenotype /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred from mutant phenotype /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // traceable author statement /// 0030018 // Z disc // inferred from direct assay /// 0030315 // T-tubule // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005102 // receptor binding // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 208921_s_at L12387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12387.1 /DEF=Human sorcin (SRI) mRNA, complete cds. /FEA=mRNA /GEN=SRI /PROD=sorcin /DB_XREF=gi:459835 /UG=Hs.300741 sorcin /FL=gb:M32886.1 gb:NM_003130.1 gb:L12387.1 L12387 sorcin SRI 6717 NM_001256891 /// NM_001256892 /// NM_003130 /// NM_198901 /// XM_006716097 0001508 // action potential // traceable author statement /// 0006508 // proteolysis // not recorded /// 0006810 // transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006880 // intracellular sequestering of iron ion // traceable author statement /// 0006942 // regulation of striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from mutant phenotype /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from mutant phenotype /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0086004 // regulation of cardiac muscle cell contraction // inferred from mutant phenotype /// 1901077 // regulation of relaxation of muscle // inferred from mutant phenotype /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from mutant phenotype /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred from mutant phenotype /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // traceable author statement /// 0030018 // Z disc // inferred from direct assay /// 0030315 // T-tubule // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005102 // receptor binding // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 208922_s_at BC004904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004904.1 /DEF=Homo sapiens, nuclear RNA export factor 1, clone MGC:4612, mRNA, complete cds. /FEA=mRNA /PROD=nuclear RNA export factor 1 /DB_XREF=gi:13436184 /UG=Hs.323502 nuclear RNA export factor 1 /FL=gb:BC004904.1 gb:U80073.1 gb:AF126246.1 gb:AF112880.1 gb:NM_006362.1 BC004904 nuclear RNA export factor 1 NXF1 10482 NM_001081491 /// NM_006362 /// XM_006718418 /// XM_006718419 /// XM_006718420 0006405 // RNA export from nucleus // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208923_at BC005097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005097.1 /DEF=Homo sapiens, Similar to selective hybridizing clone, clone MGC:13167, mRNA, complete cds. /FEA=mRNA /PROD=Similar to selective hybridizing clone /DB_XREF=gi:13477256 /UG=Hs.77257 KIAA0068 protein /FL=gb:BC005097.1 BC005097 cytoplasmic FMR1 interacting protein 1 CYFIP1 23191 NM_001033028 /// NM_001287810 /// NM_014608 /// XM_005272543 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0048675 // axon extension // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from mutant phenotype 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005845 // mRNA cap binding complex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from mutant phenotype /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from mutant phenotype /// 0048365 // Rac GTPase binding // inferred from mutant phenotype /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity 208924_at AB024703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB024703.1 /DEF=Homo sapiens mRNA for Sid1669p, complete cds. /FEA=mRNA /GEN=Sid1669 /PROD=Sid1669p /DB_XREF=gi:5931544 /UG=Hs.96334 ring finger protein 11 /FL=gb:AF151881.1 gb:AB024703.1 gb:NM_014372.1 AB024703 ring finger protein 11 RNF11 26994 NM_014372 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208925_at AF161522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF161522.1 /DEF=Homo sapiens HSPC174 mRNA, complete cds. /FEA=mRNA /PROD=HSPC174 /DB_XREF=gi:6841567 /UG=Hs.107393 chromosome 3 open reading frame 4 /FL=gb:NM_019895.1 gb:AF161522.1 AF161522 claudin domain containing 1 CLDND1 56650 NM_001040181 /// NM_001040182 /// NM_001040183 /// NM_001040184 /// NM_001040199 /// NM_001040200 /// NM_019895 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 208926_at U84246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84246.1 /DEF=Homo sapiens lysosomal sialidase mRNA, complete cds. /FEA=mRNA /PROD=lysosomal sialidase /DB_XREF=gi:4099140 /UG=Hs.118721 sialidase 1 (lysosomal sialidase) /FL=gb:BC000722.1 gb:AF040958.1 gb:U84246.1 gb:NM_000434.1 U84246 sialidase 1 (lysosomal sialidase) NEU1 4758 NM_000434 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004308 // exo-alpha-sialidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0052794 // exo-alpha-(2->3)-sialidase activity // inferred from electronic annotation /// 0052795 // exo-alpha-(2->6)-sialidase activity // inferred from electronic annotation /// 0052796 // exo-alpha-(2->8)-sialidase activity // inferred from electronic annotation 208927_at BF673888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF673888 /FEA=EST /DB_XREF=gi:11947783 /DB_XREF=est:602137554F1 /CLONE=IMAGE:4274077 /UG=Hs.129951 speckle-type POZ protein /FL=gb:BC001269.1 BF673888 speckle-type POZ protein SPOP 8405 NM_001007226 /// NM_001007227 /// NM_001007228 /// NM_001007229 /// NM_001007230 /// NM_003563 /// XM_005257723 /// XM_005257724 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 208928_at AF258341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF258341.1 /DEF=Homo sapiens NADPH-cytochrome P450 reductase mRNA, complete cds. /FEA=mRNA /PROD=NADPH-cytochrome P450 reductase /DB_XREF=gi:9964002 /UG=Hs.167246 P450 (cytochrome) oxidoreductase /FL=gb:AB051763.1 gb:AF258341.1 AF258341 P450 (cytochrome) oxidoreductase POR 5447 NM_000941 0003420 // regulation of growth plate cartilage chondrocyte proliferation // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from electronic annotation /// 0018393 // internal peptidyl-lysine acetylation // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032770 // positive regulation of monooxygenase activity // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043602 // nitrate catabolic process // inferred from electronic annotation /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046210 // nitric oxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0060192 // negative regulation of lipase activity // inferred from electronic annotation /// 0070988 // demethylation // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from electronic annotation /// 0090346 // cellular organofluorine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003958 // NADPH-hemoprotein reductase activity // inferred from direct assay /// 0003958 // NADPH-hemoprotein reductase activity // traceable author statement /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008941 // nitric oxide dioxygenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0047726 // iron-cytochrome-c reductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 208929_x_at BC004954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004954.1 /DEF=Homo sapiens, clone MGC:10897, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10897) /DB_XREF=gi:13436331 /UG=Hs.180842 ribosomal protein L13 /FL=gb:BC000851.1 gb:BC004954.1 gb:NM_000977.1 BC004954 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208930_s_at BG032366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG032366 /FEA=EST /DB_XREF=gi:12423596 /DB_XREF=est:602301349F1 /CLONE=IMAGE:4402836 /UG=Hs.256583 interleukin enhancer binding factor 3, 90kD /FL=gb:AF147209.1 gb:AF167569.1 BG032366 interleukin enhancer binding factor 3, 90kDa ILF3 3609 NM_001137673 /// NM_004516 /// NM_012218 /// NM_017620 /// NM_153464 /// XM_005259895 /// XM_006722742 0000279 // M phase // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208931_s_at AF147209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF147209.1 /DEF=Homo sapiens double-stranded RNA-binding nuclear protein DRBP76 mRNA, complete cds. /FEA=mRNA /PROD=double-stranded RNA-binding nuclear proteinDRBP76 /DB_XREF=gi:4929370 /UG=Hs.256583 interleukin enhancer binding factor 3, 90kD /FL=gb:AF147209.1 gb:AF167569.1 AF147209 interleukin enhancer binding factor 3, 90kDa ILF3 3609 NM_001137673 /// NM_004516 /// NM_012218 /// NM_017620 /// NM_153464 /// XM_005259895 /// XM_006722742 0000279 // M phase // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208932_at BC001416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001416.1 /DEF=Homo sapiens, protein phosphatase 4 (formerly X), catalytic subunit, clone MGC:1882, mRNA, complete cds. /FEA=mRNA /PROD=protein phosphatase 4 (formerly X), catalyticsubunit /DB_XREF=gi:12655126 /UG=Hs.2903 protein phosphatase 4 (formerly X), catalytic subunit /FL=gb:BC001416.1 gb:AF097996.1 gb:NM_002720.1 BC001416 protein phosphatase 4, catalytic subunit PPP4C 5531 NM_002720 /// XM_005255418 /// XM_005255419 /// XM_005255420 /// XM_005255421 /// XM_006721061 0000226 // microtubule cytoskeleton organization // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement /// 0038061 // NIK/NF-kappaB signaling // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030289 // protein phosphatase 4 complex // inferred from electronic annotation 0004704 // NF-kappaB-inducing kinase activity // non-traceable author statement /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208933_s_at AI659005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659005 /FEA=EST /DB_XREF=gi:4762575 /DB_XREF=est:tu23e02.x1 /CLONE=IMAGE:2251898 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342815.1 gb:L78132.1 gb:AF074000.1 gb:NM_006499.1 AI659005 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 208934_s_at AF342815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF342815.1 /DEF=Homo sapiens colorectal carcinoma-derived galectin-8 variant I mRNA, complete cds. /FEA=mRNA /PROD=colorectal carcinoma-derived galectin-8 variantI /DB_XREF=gi:13249298 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342815.1 gb:L78132.1 gb:AF074000.1 gb:NM_006499.1 AF342815 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 208935_s_at L78132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L78132.1 /DEF=Human prostate carcinoma tumor antigen (pcta-1) mRNA, complete cds. /FEA=mRNA /GEN=pcta-1 /PROD=prostate carcinoma tumor antigen /DB_XREF=gi:1932711 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342815.1 gb:L78132.1 gb:AF074000.1 gb:NM_006499.1 L78132 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 208936_x_at AF074000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074000.1 /DEF=Homo sapiens Po66 carbohydrate binding protein mRNA, complete cds. /FEA=mRNA /PROD=Po66 carbohydrate binding protein /DB_XREF=gi:5577965 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342815.1 gb:L78132.1 gb:AF074000.1 gb:NM_006499.1 AF074000 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 208937_s_at D13889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13889.1 /DEF=Human mRNA for Id-1H, complete cds. /FEA=mRNA /GEN=Id-1H /PROD=Id-1H /DB_XREF=gi:464181 /UG=Hs.75424 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein /FL=gb:BC000613.1 gb:NM_002165.1 gb:D13889.1 D13889 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein ID1 3397 NM_002165 /// NM_181353 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010621 // negative regulation of transcription by transcription factor localization // traceable author statement /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043534 // blood vessel endothelial cell migration // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // traceable author statement /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 208938_at BC004913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004913.1 /DEF=Homo sapiens, papillary renal cell carcinoma (translocation-associated), clone MGC:4723, mRNA, complete cds. /FEA=mRNA /PROD=papillary renal cell carcinoma(translocation-associated) /DB_XREF=gi:13436211 /UG=Hs.9629 papillary renal cell carcinoma (translocation-associated) /FL=gb:BC004913.1 gb:NM_005973.2 BC004913 papillary renal cell carcinoma (translocation-associated) PRCC 5546 NM_005973 /// NM_199416 /// XM_005245313 /// XM_005245314 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208939_at AV682679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV682679 /FEA=EST /DB_XREF=gi:10284542 /DB_XREF=est:AV682679 /CLONE=GKBACG02 /UG=Hs.124027 SELENOPHOSPHATE SYNTHETASE ; Human selenium donor protein /FL=gb:BC000941.1 AV682679 selenophosphate synthetase 1 SEPHS1 22929 NM_001195602 /// NM_001195604 /// NM_012247 /// XM_006717433 0006464 // cellular protein modification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 208940_at AI885670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885670 /FEA=EST /DB_XREF=gi:5590834 /DB_XREF=est:wl60b09.x1 /CLONE=IMAGE:2429273 /UG=Hs.124027 SELENOPHOSPHATE SYNTHETASE ; Human selenium donor protein /FL=gb:BC000941.1 AI885670 selenophosphate synthetase 1 SEPHS1 22929 NM_001195602 /// NM_001195604 /// NM_012247 /// XM_006717433 0006464 // cellular protein modification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 208941_s_at BC000941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000941.1 /DEF=Homo sapiens, SELENOPHOSPHATE SYNTHETASE ; Human selenium donor protein, clone MGC:4980, mRNA, complete cds. /FEA=mRNA /PROD=SELENOPHOSPHATE SYNTHETASE ; Human seleniumdonor protein /DB_XREF=gi:12654242 /UG=Hs.124027 SELENOPHOSPHATE SYNTHETASE ; Human selenium donor protein /FL=gb:BC000941.1 BC000941 selenophosphate synthetase 1 SEPHS1 22929 NM_001195602 /// NM_001195604 /// NM_012247 /// XM_006717433 0006464 // cellular protein modification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 208942_s_at BE866511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE866511 /FEA=EST /DB_XREF=gi:10315287 /DB_XREF=est:601678885F1 /CLONE=IMAGE:3961461 /UG=Hs.8146 translocation protein 1 /FL=gb:D87127.1 gb:U93239.1 gb:NM_003262.1 BE866511 SEC62 homolog (S. cerevisiae) SEC62 7095 NM_003262 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208943_s_at U93239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U93239.1 /DEF=Human Sec62 (Sec62) mRNA, complete cds. /FEA=mRNA /GEN=Sec62 /PROD=Sec62 /DB_XREF=gi:1928972 /UG=Hs.8146 translocation protein 1 /FL=gb:D87127.1 gb:U93239.1 gb:NM_003262.1 U93239 SEC62 homolog (S. cerevisiae) SEC62 7095 NM_003262 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 208944_at D50683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50683.1 /DEF=Homo sapiens mRNA for TGF-betaIIR alpha, complete cds. /FEA=mRNA /PROD=TGF-betaIIR alpha /DB_XREF=gi:1827474 /UG=Hs.82028 transforming growth factor, beta receptor II (70-80kD) /FL=gb:D50683.1 D50683 transforming growth factor, beta receptor II (70/80kDa) TGFBR2 7048 NM_001024847 /// NM_003242 /// XM_006713316 0001568 // blood vessel development // traceable author statement /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002651 // positive regulation of tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002663 // positive regulation of B cell tolerance induction // inferred from sequence or structural similarity /// 0002666 // positive regulation of T cell tolerance induction // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred by curator /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032924 // activin receptor signaling pathway // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0043415 // positive regulation of skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060433 // bronchus development // inferred from electronic annotation /// 0060434 // bronchus morphogenesis // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060440 // trachea formation // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred by curator /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from mutant phenotype /// 0005026 // transforming growth factor beta receptor activity, type II // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034714 // type III transforming growth factor beta receptor binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 208945_s_at NM_003766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003766.1 /DEF=Homo sapiens beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) (BECN1), mRNA. /FEA=CDS /GEN=BECN1 /PROD=beclin 1 (coiled-coil, myosin-likeBCL2-interacting protein) /DB_XREF=gi:4502394 /UG=Hs.12272 beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) /FL=gb:AF077301.1 gb:NM_003766.1 gb:AF139131.1 NM_003766 beclin 1, autophagy related BECN1 8678 NM_003766 /// XM_005257758 /// XM_005257759 /// XM_005257760 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071275 // cellular response to aluminum ion // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208946_s_at AF139131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF139131.1 /DEF=Homo sapiens beclin 1 (BECN1) mRNA, complete cds. /FEA=mRNA /GEN=BECN1 /PROD=beclin 1 /DB_XREF=gi:4680380 /UG=Hs.12272 beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) /FL=gb:AF077301.1 gb:NM_003766.1 gb:AF139131.1 AF139131 beclin 1, autophagy related BECN1 8678 NM_003766 /// XM_005257758 /// XM_005257759 /// XM_005257760 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071275 // cellular response to aluminum ion // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 208947_s_at U59323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59323.1 /DEF=Human homolog of yeast UPF1 (HUPF1) mRNA, complete cds. /FEA=mRNA /GEN=HUPF1 /PROD=homolog of yeast UPF1 /DB_XREF=gi:1633577 /UG=Hs.12719 regulator of nonsense transcripts 1 /FL=gb:U65533.1 gb:U59323.1 gb:AF074016.1 gb:NM_002911.1 U59323 UPF1 regulator of nonsense transcripts homolog (yeast) UPF1 5976 NM_002911 /// XM_005260015 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from direct assay /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006449 // regulation of translational termination // inferred from mutant phenotype /// 0006449 // regulation of translational termination // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0044530 // supraspliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208948_s_at BC000830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000830.1 /DEF=Homo sapiens, clone MGC:4921, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4921) /DB_XREF=gi:12654050 /UG=Hs.6113 staufen (Drosophila, RNA-binding protein) /FL=gb:BC000830.1 gb:AF061938.1 gb:NM_017452.1 BC000830 staufen double-stranded RNA binding protein 1 STAU1 6780 NM_001037328 /// NM_004602 /// NM_017452 /// NM_017453 /// NM_017454 /// XM_005260524 /// XM_005260525 /// XM_005260526 /// XM_005260527 /// XM_005260528 /// XM_005260529 /// XM_006723865 /// XM_006723866 /// XM_006723867 /// XM_006723868 /// XM_006723869 0008298 // intracellular mRNA localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208949_s_at BC001120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001120.1 /DEF=Homo sapiens, lectin, galactoside-binding, soluble, 3 (galectin 3), clone MGC:2058, mRNA, complete cds. /FEA=mRNA /PROD=lectin, galactoside-binding, soluble, 3(galectin 3) /DB_XREF=gi:12654570 /UG=Hs.621 lectin, galactoside-binding, soluble, 3 (galectin 3) /FL=gb:M35368.1 gb:BC001120.1 gb:M57710.1 gb:M36682.1 gb:AB006780.1 gb:NM_002306.1 BC001120 lectin, galactoside-binding, soluble, 3 LGALS3 3958 NM_001177388 /// NM_002306 /// NR_003225 0001501 // skeletal system development // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042129 // regulation of T cell proliferation // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050918 // positive chemotaxis // inferred from direct assay /// 0070232 // regulation of T cell apoptotic process // inferred from direct assay /// 0071674 // mononuclear cell migration // inferred from direct assay /// 0071677 // positive regulation of mononuclear cell migration // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000521 // negative regulation of immunological synapse formation // inferred from sequence or structural similarity /// 2001189 // negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from sequence or structural similarity /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019863 // IgE binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208950_s_at BC002515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002515.1 /DEF=Homo sapiens, antiquitin 1, clone MGC:1569, mRNA, complete cds. /FEA=mRNA /PROD=antiquitin 1 /DB_XREF=gi:12803386 /UG=Hs.74294 aldehyde dehydrogenase 7 family, member A1 /FL=gb:BC002515.1 gb:NM_001182.1 BC002515 aldehyde dehydrogenase 7 family, member A1 ALDH7A1 501 NM_001182 /// NM_001201377 /// NM_001202404 0006081 // cellular aldehyde metabolic process // inferred from sequence or structural similarity /// 0006554 // lysine catabolic process // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019285 // glycine betaine biosynthetic process from choline // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from sequence or structural similarity /// 0004043 // L-aminoadipate-semialdehyde dehydrogenase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008802 // betaine-aldehyde dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 208951_at BC002515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002515.1 /DEF=Homo sapiens, antiquitin 1, clone MGC:1569, mRNA, complete cds. /FEA=mRNA /PROD=antiquitin 1 /DB_XREF=gi:12803386 /UG=Hs.74294 aldehyde dehydrogenase 7 family, member A1 /FL=gb:BC002515.1 gb:NM_001182.1 BC002515 aldehyde dehydrogenase 7 family, member A1 ALDH7A1 501 NM_001182 /// NM_001201377 /// NM_001202404 0006081 // cellular aldehyde metabolic process // inferred from sequence or structural similarity /// 0006554 // lysine catabolic process // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019285 // glycine betaine biosynthetic process from choline // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from sequence or structural similarity /// 0004043 // L-aminoadipate-semialdehyde dehydrogenase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008802 // betaine-aldehyde dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 208952_s_at AA811923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA811923 /FEA=EST /DB_XREF=gi:2881534 /DB_XREF=est:ob72f05.s1 /CLONE=IMAGE:1336929 /UG=Hs.78851 KIAA0217 protein /FL=gb:BC003381.1 AA811923 La ribonucleoprotein domain family, member 4B LARP4B 23185 NM_015155 /// XM_005252431 /// XM_005252432 /// XM_005252433 /// XM_005252435 /// XM_006717436 0006417 // regulation of translation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208953_at AU154358 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154358 /FEA=EST /DB_XREF=gi:11015879 /DB_XREF=est:AU154358 /CLONE=NT2RP4000896 /UG=Hs.78851 KIAA0217 protein /FL=gb:BC003381.1 AU154358 La ribonucleoprotein domain family, member 4B LARP4B 23185 NM_015155 /// XM_005252431 /// XM_005252432 /// XM_005252433 /// XM_005252435 /// XM_006717436 0006417 // regulation of translation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208954_s_at BC003381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003381.1 /DEF=Homo sapiens, clone MGC:5353, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5353) /DB_XREF=gi:13097242 /UG=Hs.78851 KIAA0217 protein /FL=gb:BC003381.1 BC003381 La ribonucleoprotein domain family, member 4B LARP4B 23185 NM_015155 /// XM_005252431 /// XM_005252432 /// XM_005252433 /// XM_005252435 /// XM_006717436 0006417 // regulation of translation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208955_at AB049113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049113.1 /DEF=Homo sapiens DUT mRNA for dUTP pyrophosphatase, complete cds. /FEA=mRNA /GEN=DUT /PROD=dUTP pyrophosphatase /DB_XREF=gi:10257384 /UG=Hs.82113 dUTP pyrophosphatase /FL=gb:AB049113.1 gb:U31930.1 gb:U62891.1 gb:M89913.1 gb:NM_001948.1 AB049113 deoxyuridine triphosphatase DUT 1854 NM_001025248 /// NM_001025249 /// NM_001948 /// XM_005254211 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006226 // dUMP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046080 // dUTP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004170 // dUTP diphosphatase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208956_x_at U62891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62891.1 /DEF=Human deoxyuridine triphosphatase (DUT) mRNA, complete cds. /FEA=mRNA /GEN=DUT /PROD=deoxyuridine triphosphatase /DB_XREF=gi:1421817 /UG=Hs.82113 dUTP pyrophosphatase /FL=gb:AB049113.1 gb:U31930.1 gb:U62891.1 gb:M89913.1 gb:NM_001948.1 U62891 deoxyuridine triphosphatase DUT 1854 NM_001025248 /// NM_001025249 /// NM_001948 /// XM_005254211 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006226 // dUMP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046080 // dUTP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004170 // dUTP diphosphatase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208957_at BF439241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439241 /FEA=EST /DB_XREF=gi:11451758 /DB_XREF=est:nab61e04.x1 /CLONE=IMAGE:3270247 /UG=Hs.154023 KIAA0573 protein /FL=gb:BC005374.1 BF439241 endoplasmic reticulum protein 44 ERP44 23071 NM_015051 0006457 // protein folding // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045454 // cell redox homeostasis // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208958_at AI827677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI827677 /FEA=EST /DB_XREF=gi:5448348 /DB_XREF=est:wf32g12.x1 /CLONE=IMAGE:2357350 /UG=Hs.154023 KIAA0573 protein /FL=gb:BC005374.1 AI827677 endoplasmic reticulum protein 44 ERP44 23071 NM_015051 0006457 // protein folding // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045454 // cell redox homeostasis // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208959_s_at BC005374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005374.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 1110001E24 gene, clone MGC:12490, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 1110001E24 gene /DB_XREF=gi:13529223 /UG=Hs.154023 KIAA0573 protein /FL=gb:BC005374.1 BC005374 endoplasmic reticulum protein 44 ERP44 23071 NM_015051 0006457 // protein folding // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045454 // cell redox homeostasis // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 208960_s_at BE675435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675435 /FEA=EST /DB_XREF=gi:10035976 /DB_XREF=est:7f09a11.x1 /CLONE=IMAGE:3294140 /UG=Hs.285313 core promoter element binding protein /FL=gb:BC000311.1 gb:BC004301.1 gb:AF001461.1 gb:AB017493.1 gb:NM_001300.2 BE675435 Kruppel-like factor 6 KLF6 1316 NM_001008490 /// NM_001160124 /// NM_001160125 /// NM_001300 /// NR_027653 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208961_s_at AB017493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017493.1 /DEF=Homo sapiens mRNA for DNA-binding zinc finger(GBF), complete cds. /FEA=mRNA /PROD=DNA-binding zinc finger(GBF) /DB_XREF=gi:3582142 /UG=Hs.285313 core promoter element binding protein /FL=gb:BC000311.1 gb:BC004301.1 gb:AF001461.1 gb:AB017493.1 gb:NM_001300.2 AB017493 Kruppel-like factor 6 KLF6 1316 NM_001008490 /// NM_001160124 /// NM_001160125 /// NM_001300 /// NR_027653 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208962_s_at BE540552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE540552 /FEA=EST /DB_XREF=gi:9769197 /DB_XREF=est:601066683F1 /CLONE=IMAGE:3452925 /UG=Hs.132898 fatty acid desaturase 1 /FL=gb:AF084558.1 gb:NM_013402.2 gb:AL512760.1 gb:AF199596.1 gb:AF226273.1 BE540552 fatty acid desaturase 1 /// microRNA 1908 FADS1 /// MIR1908 3992 /// 100302263 NM_013402 /// NR_031729 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from direct assay /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0046456 // icosanoid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0000248 // C-5 sterol desaturase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 208963_x_at BG165833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG165833 /FEA=EST /DB_XREF=gi:12672536 /DB_XREF=est:602344314F1 /CLONE=IMAGE:4454523 /UG=Hs.132898 fatty acid desaturase 1 /FL=gb:AF084558.1 gb:NM_013402.2 gb:AL512760.1 gb:AF199596.1 gb:AF226273.1 BG165833 fatty acid desaturase 1 /// microRNA 1908 FADS1 /// MIR1908 3992 /// 100302263 NM_013402 /// NR_031729 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from direct assay /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0046456 // icosanoid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0000248 // C-5 sterol desaturase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 208964_s_at AL512760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL512760.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762M2311 (from clone DKFZp762M2311); complete cds. /FEA=mRNA /GEN=DKFZp762M2311 /PROD=hypothetical protein /DB_XREF=gi:12224983 /UG=Hs.132898 fatty acid desaturase 1 /FL=gb:AF084558.1 gb:NM_013402.2 gb:AL512760.1 gb:AF199596.1 gb:AF226273.1 AL512760 fatty acid desaturase 1 /// microRNA 1908 FADS1 /// MIR1908 3992 /// 100302263 NM_013402 /// NR_031729 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from direct assay /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0046456 // icosanoid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0000248 // C-5 sterol desaturase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 208965_s_at BG256677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG256677 /FEA=EST /DB_XREF=gi:12766493 /DB_XREF=est:602370865F1 /CLONE=IMAGE:4478872 /UG=Hs.155530 interferon, gamma-inducible protein 16 /FL=gb:AF208043.1 BG256677 interferon, gamma-inducible protein 16 IFI16 3428 NM_001206567 /// NM_005531 /// XM_005245127 /// XM_006711290 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // traceable author statement /// 0002218 // activation of innate immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0010506 // regulation of autophagy // inferred from expression pattern /// 0030097 // hemopoiesis // non-traceable author statement /// 0030099 // myeloid cell differentiation // non-traceable author statement /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032731 // positive regulation of interleukin-1 beta production // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208966_x_at AF208043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF208043.1 /DEF=Homo sapiens IFI16b (IFI16b) mRNA, complete cds. /FEA=mRNA /GEN=IFI16b /PROD=IFI16b /DB_XREF=gi:6644296 /UG=Hs.155530 interferon, gamma-inducible protein 16 /FL=gb:AF208043.1 AF208043 interferon, gamma-inducible protein 16 IFI16 3428 NM_001206567 /// NM_005531 /// XM_005245127 /// XM_006711290 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // traceable author statement /// 0002218 // activation of innate immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0010506 // regulation of autophagy // inferred from expression pattern /// 0030097 // hemopoiesis // non-traceable author statement /// 0030099 // myeloid cell differentiation // non-traceable author statement /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032731 // positive regulation of interleukin-1 beta production // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 208967_s_at U39945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39945.1 /DEF=Human adenylate kinase 2 (adk2) mRNA, complete cds. /FEA=mRNA /GEN=adk2 /PROD=adenylate kinase 2 /DB_XREF=gi:1209686 /UG=Hs.171811 adenylate kinase 2 /FL=gb:U39945.1 gb:U84371.1 gb:NM_001625.1 U39945 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 208968_s_at BC002568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002568.1 /DEF=Homo sapiens, hypothetical protein, clone MGC:2478, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:12803484 /UG=Hs.4900 hypothetical protein /FL=gb:AF248964.1 gb:BC002568.1 gb:AF116609.1 BC002568 cytokine induced apoptosis inhibitor 1 CIAPIN1 57019 NM_020313 /// XM_005256061 /// XM_005256062 /// XM_005256063 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 208969_at AF050641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF050641.1 /DEF=Homo sapiens NADH-ubiquinone oxidoreductase 39kDa subunit mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=NADH-ubiquinone oxidoreductase 39kDa subunit /DB_XREF=gi:5326822 /UG=Hs.75227 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 (39kD) /FL=gb:AF050641.1 gb:NM_005002.1 AF050641 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa NDUFA9 4704 NM_005002 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0003954 // NADH dehydrogenase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 208970_s_at M14016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M14016.1 /DEF=Human uroporphyrinogen decarboxylase mRNA, complete cds. /FEA=mRNA /GEN=UROD /DB_XREF=gi:340180 /UG=Hs.78601 uroporphyrinogen decarboxylase /FL=gb:BC001778.1 gb:M14016.1 gb:AF104421.1 gb:AF104422.1 gb:AF104423.1 gb:AF104424.1 gb:AF104425.1 gb:AF104426.1 gb:AF104427.1 gb:AF104428.1 gb:AF104429.1 gb:AF104430.1 gb:AF104431.1 gb:AF104432.1 gb:AF104433.1 gb:AF104434.1 gb:AF104435.1 gb:AF104436.1 gb:AF104437.1 gb:AF104438.1 gb:AF104439.1 gb:AF104440.1 gb:NM_000374.2 M14016 uroporphyrinogen decarboxylase UROD 7389 NM_000374 /// NR_036510 /// XM_005271169 /// XM_005271170 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // traceable author statement /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0004853 // uroporphyrinogen decarboxylase activity // inferred from direct assay /// 0004853 // uroporphyrinogen decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 208971_at M14016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M14016.1 /DEF=Human uroporphyrinogen decarboxylase mRNA, complete cds. /FEA=mRNA /GEN=UROD /DB_XREF=gi:340180 /UG=Hs.78601 uroporphyrinogen decarboxylase /FL=gb:BC001778.1 gb:M14016.1 gb:AF104421.1 gb:AF104422.1 gb:AF104423.1 gb:AF104424.1 gb:AF104425.1 gb:AF104426.1 gb:AF104427.1 gb:AF104428.1 gb:AF104429.1 gb:AF104430.1 gb:AF104431.1 gb:AF104432.1 gb:AF104433.1 gb:AF104434.1 gb:AF104435.1 gb:AF104436.1 gb:AF104437.1 gb:AF104438.1 gb:AF104439.1 gb:AF104440.1 gb:NM_000374.2 M14016 uroporphyrinogen decarboxylase UROD 7389 NM_000374 /// NR_036510 /// XM_005271169 /// XM_005271170 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // traceable author statement /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0004853 // uroporphyrinogen decarboxylase activity // inferred from direct assay /// 0004853 // uroporphyrinogen decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 208972_s_at AL080089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080089.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564L2362 (from clone DKFZp564L2362); complete cds. /FEA=mRNA /GEN=DKFZp564L2362 /PROD=hypothetical protein /DB_XREF=gi:5262506 /UG=Hs.80986 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 /FL=gb:BC004963.1 gb:D13118.1 gb:AL080089.1 AL080089 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) ATP5G1 516 NM_001002027 /// NM_005175 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 208973_at BC001072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001072.1 /DEF=Homo sapiens, clone MGC:2683, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2683) /DB_XREF=gi:12654484 /UG=Hs.151032 hypothetical protein MGC2683 /FL=gb:BC001072.1 gb:BC004456.1 BC001072 ERI1 exoribonuclease family member 3 ERI3 79033 NM_024066 /// XM_005271184 /// XM_005271186 /// XM_005271187 /// XM_005271188 /// XM_005271189 /// XM_006710891 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208974_x_at BC003572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003572.1 /DEF=Homo sapiens, karyopherin (importin) beta 1, clone MGC:2156, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin (importin) beta 1 /DB_XREF=gi:13097743 /UG=Hs.180446 karyopherin (importin) beta 1 /FL=gb:BC003572.1 gb:NM_002265.1 gb:L38951.1 BC003572 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208975_s_at L38951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L38951.1 /DEF=Homo sapiens importin beta subunit mRNA, complete cds. /FEA=mRNA /PROD=importin beta subunit /DB_XREF=gi:893287 /UG=Hs.180446 karyopherin (importin) beta 1 /FL=gb:BC003572.1 gb:NM_002265.1 gb:L38951.1 L38951 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208977_x_at BC004188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004188.1 /DEF=Homo sapiens, tubulin, beta, 2, clone MGC:2826, mRNA, complete cds. /FEA=mRNA /PROD=tubulin, beta, 2 /DB_XREF=gi:13278848 /UG=Hs.251653 tubulin, beta, 2 /FL=gb:BC002783.1 gb:BC002885.1 gb:BC001911.1 gb:BC004188.1 gb:NM_006088.1 BC004188 tubulin, beta 4B class IVb TUBB4B 10383 NM_006088 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 208978_at U36190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36190.1 /DEF=Human cysteine-rich protein 2 (hCRP2) mRNA, complete cds. /FEA=mRNA /GEN=hCRP2 /PROD=cysteine-rich protein 2 /DB_XREF=gi:1399027 /UG=Hs.70327 cysteine-rich protein 2 /FL=gb:D42123.1 gb:BC000434.1 gb:BC001931.1 gb:U36190.1 gb:NM_001312.1 U36190 cysteine-rich protein 2 CRIP2 1397 NM_001270837 /// NM_001270841 /// NM_001312 /// NR_073081 /// NR_073082 /// NR_073083 /// NR_073084 /// NR_073085 /// XR_429291 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation 0005938 // cell cortex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 208979_at AF128458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF128458.1 /DEF=Homo sapiens nuclear receptor coactivator RAP250 mRNA, complete cds. /FEA=mRNA /PROD=nuclear receptor coactivator RAP250 /DB_XREF=gi:7140573 /UG=Hs.159613 thyroid hormone receptor binding protein /FL=gb:AF177388.1 gb:AF208227.1 gb:AF128458.1 gb:NM_014071.1 gb:AF171667.1 gb:AF245115.1 AF128458 nuclear receptor coactivator 6 NCOA6 23054 NM_001242539 /// NM_014071 /// XM_005260348 /// XM_006723750 /// XM_006723751 /// XM_006723752 /// XM_006723753 /// XM_006723754 /// XM_006723755 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0009725 // response to hormone // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // traceable author statement /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0046965 // retinoid X receptor binding // traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 208980_s_at M26880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M26880.1 /DEF=Human ubiquitin mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:340067 /UG=Hs.183704 ubiquitin C /FL=gb:M17597.1 gb:M26880.1 M26880 ubiquitin C UBC 7316 NM_021009 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208981_at AA702701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA702701 /FEA=EST /DB_XREF=gi:2705814 /DB_XREF=est:zi90h02.s1 /CLONE=IMAGE:448083 /UG=Hs.78146 plateletendothelial cell adhesion molecule (CD31 antigen) /FL=gb:M37780.1 gb:M28526.1 gb:NM_000442.1 AA702701 platelet/endothelial cell adhesion molecule 1 PECAM1 5175 NM_000442 /// XM_005276880 /// XM_005276881 /// XM_005276882 /// XM_005276883 /// XM_006721944 /// XM_006721945 0002576 // platelet degranulation // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050904 // diapedesis // inferred from direct assay /// 0072011 // glomerular endothelium development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208982_at AW574504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW574504 /FEA=EST /DB_XREF=gi:7246055 /DB_XREF=est:UI-HF-BK0-aab-h-05-0-UI.s1 /CLONE=IMAGE:3053409 /UG=Hs.78146 plateletendothelial cell adhesion molecule (CD31 antigen) /FL=gb:M37780.1 gb:M28526.1 gb:NM_000442.1 AW574504 platelet/endothelial cell adhesion molecule 1 PECAM1 5175 NM_000442 /// XM_005276880 /// XM_005276881 /// XM_005276882 /// XM_005276883 /// XM_006721944 /// XM_006721945 0002576 // platelet degranulation // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050904 // diapedesis // inferred from direct assay /// 0072011 // glomerular endothelium development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208983_s_at M37780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M37780.1 /DEF=Human leukocyte surface protein (CD31) mRNA, complete cds. /FEA=mRNA /GEN=CD31 /PROD=leukocyte surface protein /DB_XREF=gi:187239 /UG=Hs.78146 plateletendothelial cell adhesion molecule (CD31 antigen) /FL=gb:M37780.1 gb:M28526.1 gb:NM_000442.1 M37780 platelet/endothelial cell adhesion molecule 1 PECAM1 5175 NM_000442 /// XM_005276880 /// XM_005276881 /// XM_005276882 /// XM_005276883 /// XM_006721944 /// XM_006721945 0002576 // platelet degranulation // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050904 // diapedesis // inferred from direct assay /// 0072011 // glomerular endothelium development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 208984_x_at BC004181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004181.1 /DEF=Homo sapiens, Similar to RNA binding motif protein 5, clone MGC:2794, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RNA binding motif protein 5 /DB_XREF=gi:13278827 /UG=Hs.154583 RNA binding motif protein 10 /FL=gb:BC004181.1 BC004181 RNA binding motif protein 10 RBM10 8241 NM_001204466 /// NM_001204467 /// NM_001204468 /// NM_005676 /// NM_152856 /// XM_005272677 /// XM_005272678 /// XM_005272679 /// XM_006724563 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0034391 // regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 208985_s_at BC002719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002719.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD), clone MGC:3801, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 3,subunit 1 (alpha, 35kD) /DB_XREF=gi:12803762 /UG=Hs.173987 eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD) /FL=gb:BC002719.1 gb:AF090923.1 BC002719 eukaryotic translation initiation factor 3, subunit J EIF3J 8669 NM_001284335 /// NM_001284336 /// NM_003758 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 208986_at AL559478 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL559478 /FEA=EST /DB_XREF=gi:12905019 /DB_XREF=est:AL559478 /CLONE=CS0DJ013YM17 (5 prime) /UG=Hs.21704 transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) /FL=gb:M80627.1 gb:M83233.1 gb:NM_003205.2 AL559478 transcription factor 12 TCF12 6938 NM_003205 /// NM_207036 /// NM_207037 /// NM_207038 /// NM_207040 /// XM_005254613 /// XM_006720658 /// XM_006720659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from electronic annotation 208987_s_at AK024505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024505.1 /DEF=Homo sapiens mRNA for FLJ00115 protein, partial cds. /FEA=mRNA /GEN=FLJ00115 /PROD=FLJ00115 protein /DB_XREF=gi:10440529 /UG=Hs.219614 f-box and leucine-rich repeat protein 11 /FL=gb:AF179221.1 AK024505 lysine (K)-specific demethylase 2A KDM2A 22992 NM_001256405 /// NM_012308 /// NR_027473 /// XM_006718479 /// XM_006718480 /// XM_006718481 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0045322 // unmethylated CpG binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 208988_at BE675843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675843 /FEA=EST /DB_XREF=gi:10036384 /DB_XREF=est:7f17b04.x1 /CLONE=IMAGE:3294895 /UG=Hs.219614 f-box and leucine-rich repeat protein 11 /FL=gb:AF179221.1 BE675843 lysine (K)-specific demethylase 2A KDM2A 22992 NM_001256405 /// NM_012308 /// NR_027473 /// XM_006718479 /// XM_006718480 /// XM_006718481 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0045322 // unmethylated CpG binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 208989_s_at AF179221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF179221.1 /DEF=Homo sapiens F-box protein Lilina (LILINA) mRNA, complete cds. /FEA=mRNA /GEN=LILINA /PROD=F-box protein Lilina /DB_XREF=gi:5917729 /UG=Hs.219614 f-box and leucine-rich repeat protein 11 /FL=gb:AF179221.1 AF179221 lysine (K)-specific demethylase 2A KDM2A 22992 NM_001256405 /// NM_012308 /// NR_027473 /// XM_006718479 /// XM_006718480 /// XM_006718481 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0045322 // unmethylated CpG binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 208990_s_at AF132362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF132362.1 /DEF=Homo sapiens hnRNP 2H9B mRNA, complete cds. /FEA=mRNA /PROD=hnRNP 2H9B /DB_XREF=gi:7739444 /UG=Hs.279681 heterogeneous nuclear ribonucleoprotein H3 (2H9) /FL=gb:AF132362.1 AF132362 heterogeneous nuclear ribonucleoprotein H3 (2H9) HNRNPH3 3189 NM_012207 /// NM_021644 /// XM_005269748 /// XM_005269749 /// XM_005269751 /// XM_005269752 /// XM_005269753 /// XM_005269754 /// XM_006717816 /// XM_006717817 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 208991_at AA634272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA634272 /FEA=EST /DB_XREF=gi:2557486 /DB_XREF=est:ac75h05.s1 /CLONE=IMAGE:868473 /UG=Hs.321677 signal transducer and activator of transcription 3 (acute-phase response factor) /FL=gb:BC000627.1 gb:NM_003150.1 gb:L29277.1 AA634272 signal transducer and activator of transcription 3 (acute-phase response factor) STAT3 6774 NM_003150 /// NM_139276 /// NM_213662 /// XM_005257616 /// XM_005257617 /// XM_005257618 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001754 // eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from sequence or structural similarity /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042755 // eating behavior // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048708 // astrocyte differentiation // inferred from sequence or structural similarity /// 0060019 // radial glial cell differentiation // inferred from sequence or structural similarity /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from direct assay /// 2001223 // negative regulation of neuron migration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 208992_s_at BC000627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000627.1 /DEF=Homo sapiens, Signal transducer and activator of transcription 3, clone MGC:1607, mRNA, complete cds. /FEA=mRNA /PROD=Signal transducer and activator of transcription3 /DB_XREF=gi:12653684 /UG=Hs.321677 signal transducer and activator of transcription 3 (acute-phase response factor) /FL=gb:BC000627.1 gb:NM_003150.1 gb:L29277.1 BC000627 signal transducer and activator of transcription 3 (acute-phase response factor) STAT3 6774 NM_003150 /// NM_139276 /// NM_213662 /// XM_005257616 /// XM_005257617 /// XM_005257618 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001754 // eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from sequence or structural similarity /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042755 // eating behavior // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048708 // astrocyte differentiation // inferred from sequence or structural similarity /// 0060019 // radial glial cell differentiation // inferred from sequence or structural similarity /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from direct assay /// 2001223 // negative regulation of neuron migration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 208993_s_at AW340788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW340788 /FEA=EST /DB_XREF=gi:6837414 /DB_XREF=est:ha12h05.x1 /CLONE=IMAGE:2873529 /UG=Hs.77965 peptidyl-prolyl isomerase G (cyclophilin G) /FL=gb:U40763.1 gb:NM_004792.1 AW340788 peptidylprolyl isomerase G (cyclophilin G) PPIG 9360 NM_004792 /// XM_005246966 /// XM_005246967 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208994_s_at AI638762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI638762 /FEA=EST /DB_XREF=gi:4690996 /DB_XREF=est:tt32a04.x1 /CLONE=IMAGE:2242446 /UG=Hs.77965 peptidyl-prolyl isomerase G (cyclophilin G) /FL=gb:U40763.1 gb:NM_004792.1 AI638762 peptidylprolyl isomerase G (cyclophilin G) PPIG 9360 NM_004792 /// XM_005246966 /// XM_005246967 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208995_s_at U40763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U40763.1 /DEF=Human Clk-associated RS cyclophilin CARS-Cyp mRNA, complete cds. /FEA=mRNA /PROD=CARS-Cyp /DB_XREF=gi:1117967 /UG=Hs.77965 peptidyl-prolyl isomerase G (cyclophilin G) /FL=gb:U40763.1 gb:NM_004792.1 U40763 peptidylprolyl isomerase G (cyclophilin G) PPIG 9360 NM_004792 /// XM_005246966 /// XM_005246967 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 208996_s_at BC000409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000409.1 /DEF=Homo sapiens, polymerase (RNA) II (DNA directed) polypeptide C (33kD), clone MGC:8577, mRNA, complete cds. /FEA=mRNA /PROD=polymerase (RNA) II (DNA directed) polypeptide C(33kD) /DB_XREF=gi:12653280 /UG=Hs.79402 polymerase (RNA) II (DNA directed) polypeptide C (33kD) /FL=gb:BC000409.1 gb:BC003159.1 gb:AF008443.1 gb:NM_002694.1 BC000409 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa POLR2C 5432 NM_002694 /// NM_032940 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 208997_s_at U82819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82819.1 /DEF=Homo sapiens UCP2 mRNA, complete cds. /FEA=mRNA /PROD=UCP2 /DB_XREF=gi:1877473 /UG=Hs.80658 uncoupling protein 2 (mitochondrial, proton carrier) /FL=gb:NM_003355.2 gb:U76367.1 gb:U82819.1 gb:U94592.1 U82819 uncoupling protein 2 (mitochondrial, proton carrier) UCP2 7351 NM_003355 0000303 // response to superoxide // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034198 // cellular response to amino acid starvation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0097421 // liver regeneration // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 208998_at U94592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94592.1 /DEF=Human uncoupling protein homolog (UCPH) mRNA, complete cds. /FEA=mRNA /GEN=UCPH /PROD=uncoupling protein homolog /DB_XREF=gi:2052354 /UG=Hs.80658 uncoupling protein 2 (mitochondrial, proton carrier) /FL=gb:NM_003355.2 gb:U76367.1 gb:U82819.1 gb:U94592.1 U94592 uncoupling protein 2 (mitochondrial, proton carrier) UCP2 7351 NM_003355 0000303 // response to superoxide // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008016 // regulation of heart contraction // inferred by curator /// 0008584 // male gonad development // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016458 // gene silencing // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034198 // cellular response to amino acid starvation // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060306 // regulation of membrane repolarization // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060454 // positive regulation of gastric acid secretion // inferred from electronic annotation /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // traceable author statement /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0097421 // liver regeneration // inferred from electronic annotation /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008157 // protein phosphatase 1 binding // inferred from direct assay /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0086089 // voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0097110 // scaffold protein binding // inferred from physical interaction /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 208999_at D86957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D86957.1 /DEF=Human mRNA for KIAA0202 gene, partial cds. /FEA=mRNA /GEN=KIAA0202 /DB_XREF=gi:1503987 /UG=Hs.80712 KIAA0202 protein /FL=gb:BC001329.1 D86957 septin 8 SEPT8 23176 NM_001098811 /// NM_001098812 /// NM_001098813 /// NM_015146 /// XM_005271927 /// XM_005271928 /// XM_005271929 /// XM_005271930 /// XM_005271931 0007049 // cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 209000_s_at BC001329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001329.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ10849, clone MGC:5557, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ10849 /DB_XREF=gi:12654962 /UG=Hs.80712 KIAA0202 protein /FL=gb:BC001329.1 BC001329 septin 8 SEPT8 23176 NM_001098811 /// NM_001098812 /// NM_001098813 /// NM_015146 /// XM_005271927 /// XM_005271928 /// XM_005271929 /// XM_005271930 /// XM_005271931 0007049 // cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 209001_s_at BC005398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005398.1 /DEF=Homo sapiens, clone MGC:12537, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12537) /DB_XREF=gi:13529286 /UG=Hs.106909 DKFZP566D193 protein /FL=gb:BC005398.1 BC005398 anaphase promoting complex subunit 13 ANAPC13 25847 NM_001242374 /// NM_001242375 /// NM_015391 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005680 // anaphase-promoting complex // inferred from direct assay 209002_s_at BC003177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003177.1 /DEF=Homo sapiens, KIAA1536 protein, clone MGC:4414, mRNA, complete cds. /FEA=mRNA /PROD=KIAA1536 protein /DB_XREF=gi:13112006 /UG=Hs.156667 KIAA1536 protein /FL=gb:AL136895.1 gb:BC003177.1 BC003177 calcium binding and coiled-coil domain 1 CALCOCO1 57658 NM_001143682 /// NM_020898 /// NR_026554 /// XM_006719523 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 209003_at AF070548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070548.1 /DEF=Homo sapiens clone 24408 2-oxoglutarate carrier protein mRNA, complete cds. /FEA=mRNA /PROD=2-oxoglutarate carrier protein /DB_XREF=gi:3387910 /UG=Hs.184877 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 /FL=gb:AF070548.1 AF070548 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 SLC25A11 8402 NM_001165417 /// NM_001165418 /// NM_003562 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // traceable author statement /// 0015742 // alpha-ketoglutarate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015367 // oxoglutarate:malate antiporter activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 209004_s_at AF142481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF142481.1 /DEF=Homo sapiens F-box protein FLR1 (FLR1) mRNA, complete cds. /FEA=mRNA /GEN=FLR1 /PROD=F-box protein FLR1 /DB_XREF=gi:7672733 /UG=Hs.5548 f-box and leucine-rich repeat protein 5 /FL=gb:AF199420.1 gb:AF142481.1 gb:AF157323.1 AF142481 F-box and leucine-rich repeat protein 5 FBXL5 26234 NM_001193534 /// NM_001193535 /// NM_012161 /// NR_036464 /// XM_006713959 /// XM_006713960 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from expression pattern /// 0055072 // iron ion homeostasis // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209005_at AF157323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF157323.1 /DEF=Homo sapiens p45SKP2-like protein mRNA, complete cds. /FEA=mRNA /PROD=p45SKP2-like protein /DB_XREF=gi:7688696 /UG=Hs.5548 f-box and leucine-rich repeat protein 5 /FL=gb:AF199420.1 gb:AF142481.1 gb:AF157323.1 AF157323 F-box and leucine-rich repeat protein 5 FBXL5 26234 NM_001193534 /// NM_001193535 /// NM_012161 /// NR_036464 /// XM_006713959 /// XM_006713960 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from expression pattern /// 0055072 // iron ion homeostasis // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209006_s_at AF247168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF247168.1 /DEF=Homo sapiens NPD014 (NPD014) mRNA, complete cds. /FEA=mRNA /GEN=NPD014 /PROD=NPD014 /DB_XREF=gi:12005626 /UG=Hs.8084 hypothetical protein dJ465N24.2.1 /FL=gb:AF247168.1 gb:AF267856.1 AF247168 uncharacterized LOC101928189 /// arginine/serine-rich protein 1 LOC101928189 /// RSRP1 57035 /// 101928189 NM_020317 /// NM_207035 /// XR_241200 /// XR_241201 /// XR_241226 /// XR_248757 /// XR_250715 /// XR_425130 /// XR_426623 /// XR_426670 /// XR_431144 209007_s_at AF267856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF267856.1 /DEF=Homo sapiens HT033 mRNA, complete cds. /FEA=mRNA /PROD=HT033 /DB_XREF=gi:12006038 /UG=Hs.8084 hypothetical protein dJ465N24.2.1 /FL=gb:AF247168.1 gb:AF267856.1 AF267856 uncharacterized LOC101928189 /// arginine/serine-rich protein 1 LOC101928189 /// RSRP1 57035 /// 101928189 NM_020317 /// NM_207035 /// XR_241200 /// XR_241201 /// XR_241226 /// XR_248757 /// XR_250715 /// XR_425130 /// XR_426623 /// XR_426670 /// XR_431144 209008_x_at U76549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U76549.1 /DEF=Human cytokeratin 8 mRNA, complete cds. /FEA=mRNA /PROD=cytokeratin 8 /DB_XREF=gi:1673574 /UG=Hs.242463 keratin 8 /FL=gb:BC000654.1 gb:U76549.1 gb:M34225.1 gb:M26324.1 gb:NM_002273.1 U76549 keratin 8 KRT8 3856 NM_001256282 /// NM_001256293 /// NM_002273 /// NR_045962 0006915 // apoptotic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0051599 // response to hydrostatic pressure // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction 209009_at BC001169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001169.1 /DEF=Homo sapiens, Similar to esterase 10, clone MGC:1873, mRNA, complete cds. /FEA=mRNA /PROD=Similar to esterase 10 /DB_XREF=gi:12654662 /UG=Hs.82193 esterase Dformylglutathione hydrolase /FL=gb:BC001169.1 gb:AF112219.1 BC001169 esterase D ESD 2098 NM_001984 /// XM_005266278 0006508 // proteolysis // inferred from electronic annotation /// 0046294 // formaldehyde catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from direct assay /// 0018738 // S-formylglutathione hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // non-traceable author statement 209010_s_at AI797657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI797657 /FEA=EST /DB_XREF=gi:5363129 /DB_XREF=est:we90a06.x1 /CLONE=IMAGE:2348338 /UG=Hs.171957 triple functional domain (PTPRF interacting) /FL=gb:AF091395.1 AI797657 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 209011_at BF223718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223718 /FEA=EST /DB_XREF=gi:11130896 /DB_XREF=est:7q34g07.x1 /CLONE=IMAGE:3700405 /UG=Hs.171957 triple functional domain (PTPRF interacting) /FL=gb:AF091395.1 BF223718 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 209012_at AV718192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV718192 /FEA=EST /DB_XREF=gi:10815344 /DB_XREF=est:AV718192 /CLONE=FHTAABE08 /UG=Hs.171957 triple functional domain (PTPRF interacting) /FL=gb:AF091395.1 AV718192 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 209013_x_at AF091395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF091395.1 /DEF=Homo sapiens Trio isoform mRNA, complete cds. /FEA=mRNA /PROD=Trio isoform /DB_XREF=gi:3644047 /UG=Hs.171957 triple functional domain (PTPRF interacting) /FL=gb:AF091395.1 AF091395 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 209014_at AF217963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF217963.1 /DEF=Homo sapiens NRAGE mRNA, complete cds. /FEA=mRNA /PROD=NRAGE /DB_XREF=gi:9963809 /UG=Hs.177556 melanoma antigen, family D, 1 /FL=gb:AF132205.1 gb:AF124440.1 gb:NM_006986.1 gb:AF217963.1 AF217963 melanoma antigen family D, 1 MAGED1 9500 NM_001005332 /// NM_001005333 /// NM_006986 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209015_s_at BC002446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002446.1 /DEF=Homo sapiens, MRJ gene for a member of the DNAJ protein family, clone MGC:1152, mRNA, complete cds. /FEA=mRNA /PROD=MRJ gene for a member of the DNAJ proteinfamily /DB_XREF=gi:12803262 /UG=Hs.181195 DnaJ (Hsp40) homolog, subfamily B, member 6 /FL=gb:BC002446.1 gb:AB015798.1 BC002446 DnaJ (Hsp40) homolog, subfamily B, member 6 DNAJB6 10049 NM_005494 /// NM_058246 /// XM_005249515 /// XM_005249516 /// XM_006715823 0006457 // protein folding // inferred from direct assay /// 0006986 // response to unfolded protein // non-traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045109 // intermediate filament organization // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060715 // syncytiotrophoblast cell differentiation involved in labyrinthine layer development // inferred from electronic annotation /// 0060717 // chorion development // inferred from electronic annotation /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 209016_s_at BC002700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002700.1 /DEF=Homo sapiens, Similar to keratin 7, clone MGC:3625, mRNA, complete cds. /FEA=mRNA /PROD=Similar to keratin 7 /DB_XREF=gi:12803726 /UG=Hs.23881 keratin 7 /FL=gb:BC002700.1 gb:NM_005556.1 BC002700 keratin 7 KRT7 3855 NM_005556 /// XR_245927 0007010 // cytoskeleton organization // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0046417 // chorismate metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209017_s_at U02389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U02389.1 /DEF=Human hLON ATP-dependent protease mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=hLON ATP-dependent protease /DB_XREF=gi:639426 /UG=Hs.278614 protease, serine, 15 /FL=gb:BC000235.1 gb:NM_004793.1 gb:U02389.1 U02389 lon peptidase 1, mitochondrial LONP1 9361 NM_001276479 /// NM_001276480 /// NM_004793 /// NR_076392 0000002 // mitochondrial genome maintenance // non-traceable author statement /// 0001666 // response to hypoxia // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010044 // response to aluminum ion // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // non-traceable author statement /// 0034599 // cellular response to oxidative stress // inferred by curator /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0051131 // chaperone-mediated protein complex assembly // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0070407 // oxidation-dependent protein catabolic process // inferred from mutant phenotype /// 0090296 // regulation of mitochondrial DNA replication // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from mutant phenotype /// 0016020 // membrane // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004176 // ATP-dependent peptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0051880 // G-quadruplex DNA binding // inferred from direct assay /// 0070182 // DNA polymerase binding // inferred from physical interaction /// 0070361 // mitochondrial light strand promoter anti-sense binding // inferred from direct assay /// 0070362 // mitochondrial heavy strand promoter anti-sense binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay /// 0070364 // mitochondrial heavy strand promoter sense binding // inferred from direct assay 209018_s_at BF432478 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432478 /FEA=EST /DB_XREF=gi:11444621 /DB_XREF=est:nac55d04.x1 /CLONE=IMAGE:3406494 /UG=Hs.6163 Homo sapiens protein kinase BRPK mRNA, complete cds /FL=gb:AF316873.1 BF432478 PTEN induced putative kinase 1 PINK1 65018 NM_032409 0000422 // mitochondrion degradation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0032226 // positive regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0033605 // positive regulation of catecholamine secretion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097237 // cellular response to toxic substance // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0010857 // calcium-dependent protein kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055131 // C3HC4-type RING finger domain binding // inferred from physical interaction 209019_s_at AF316873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF316873.1 /DEF=Homo sapiens protein kinase BRPK mRNA, complete cds. /FEA=mRNA /PROD=protein kinase BRPK /DB_XREF=gi:13492051 /UG=Hs.6163 Homo sapiens protein kinase BRPK mRNA, complete cds /FL=gb:AF316873.1 AF316873 PTEN induced putative kinase 1 PINK1 65018 NM_032409 0000422 // mitochondrion degradation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0032226 // positive regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0033605 // positive regulation of catecholamine secretion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097237 // cellular response to toxic substance // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0010857 // calcium-dependent protein kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055131 // C3HC4-type RING finger domain binding // inferred from physical interaction 209020_at AF217514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF217514.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM038 mRNA, complete cds. /FEA=mRNA /PROD=uncharacterized bone marrow protein BM038 /DB_XREF=gi:7688970 /UG=Hs.75798 hypothetical protein /FL=gb:AF161517.1 gb:AF151041.1 gb:AF217514.1 gb:NM_016470.1 AF217514 oxidative stress responsive serine-rich 1 OSER1 51526 NM_016470 /// XM_005260424 /// XM_005260425 /// XM_006723803 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation 209021_x_at BC001331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001331.1 /DEF=Homo sapiens, Similar to KIAA0652 gene product, clone MGC:5568, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0652 gene product /DB_XREF=gi:12654966 /UG=Hs.79672 KIAA0652 gene product /FL=gb:BC001331.1 gb:BC002378.1 BC001331 autophagy related 13 ATG13 9776 NM_001142673 /// NM_001205119 /// NM_001205120 /// NM_001205121 /// NM_001205122 /// NM_014741 /// XM_005253262 /// XM_005253263 /// XM_005253265 /// XM_005253266 /// XM_005253268 /// XM_006718394 /// XM_006718395 /// XM_006718396 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0034273 // Atg1p signaling complex // /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 209022_at AK026678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026678.1 /DEF=Homo sapiens cDNA: FLJ23025 fis, clone LNG01702, highly similar to HUMAUTOND Human autonomously replicating sequence (ARS) mRNA. /FEA=mRNA /DB_XREF=gi:10439584 /UG=Hs.8217 stromal antigen 2 /FL=gb:BC001765.1 AK026678 stromal antigen 2 STAG2 10735 NM_001042749 /// NM_001042750 /// NM_001042751 /// NM_001282418 /// NM_006603 /// XM_005262357 /// XM_005262358 /// XM_005262359 /// XM_005262360 /// XM_005262361 /// XM_006724727 /// XM_006724728 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209023_s_at BC001765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001765.1 /DEF=Homo sapiens, Similar to stromal antigen 2, clone MGC:1282, mRNA, complete cds. /FEA=mRNA /PROD=Similar to stromal antigen 2 /DB_XREF=gi:12804678 /UG=Hs.8217 stromal antigen 2 /FL=gb:BC001765.1 BC001765 stromal antigen 2 STAG2 10735 NM_001042749 /// NM_001042750 /// NM_001042751 /// NM_001282418 /// NM_006603 /// XM_005262357 /// XM_005262358 /// XM_005262359 /// XM_005262360 /// XM_005262361 /// XM_006724727 /// XM_006724728 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209024_s_at AI472757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI472757 /FEA=EST /DB_XREF=gi:4325802 /DB_XREF=est:ta13e05.x1 /CLONE=IMAGE:2043968 /UG=Hs.155489 NS1-associated protein 1 /FL=gb:AF037448.1 AI472757 synaptotagmin binding, cytoplasmic RNA interacting protein SYNCRIP 10492 NM_001159673 /// NM_001159674 /// NM_001159675 /// NM_001159676 /// NM_001159677 /// NM_001253771 /// NM_006372 /// XM_005248635 /// XM_005248636 /// XM_005248637 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209025_s_at AF037448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037448.1 /DEF=Homo sapiens RRM RNA binding protein Gry-rbp (GRY-RBP) mRNA, complete cds. /FEA=mRNA /GEN=GRY-RBP /PROD=Gry-rbp /DB_XREF=gi:3037012 /UG=Hs.155489 NS1-associated protein 1 /FL=gb:AF037448.1 AF037448 synaptotagmin binding, cytoplasmic RNA interacting protein SYNCRIP 10492 NM_001159673 /// NM_001159674 /// NM_001159675 /// NM_001159676 /// NM_001159677 /// NM_001253771 /// NM_006372 /// XM_005248635 /// XM_005248636 /// XM_005248637 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209026_x_at AF141349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF141349.1 /DEF=Homo sapiens beta-tubulin mRNA, complete cds. /FEA=mRNA /PROD=beta-tubulin /DB_XREF=gi:4929137 /UG=Hs.179661 tubulin, beta polypeptide /FL=gb:BC000222.1 gb:BC002347.1 gb:BC001938.1 gb:AF070561.1 gb:AF070593.1 gb:AF070600.1 gb:AF141349.1 AF141349 tubulin, beta class I TUBB 203068 NM_001293212 /// NM_001293213 /// NM_001293214 /// NM_001293215 /// NM_001293216 /// NM_178014 /// NR_120608 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0009987 // cellular process // inferred from direct assay /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay 209027_s_at BF673013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF673013 /FEA=EST /DB_XREF=gi:11946908 /DB_XREF=est:602152905F1 /CLONE=IMAGE:4293985 /UG=Hs.24752 spectrin SH3 domain binding protein 1 /FL=gb:AF006516.1 BF673013 abl-interactor 1 ABI1 10006 NM_001012750 /// NM_001012751 /// NM_001012752 /// NM_001178116 /// NM_001178119 /// NM_001178120 /// NM_001178121 /// NM_001178122 /// NM_001178123 /// NM_001178124 /// NM_001178125 /// NM_005470 /// XM_005252332 /// XM_005252333 /// XM_006717359 /// XM_006717360 /// XM_006717361 0001756 // somitogenesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 209028_s_at AF006516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006516.1 /DEF=Homo sapiens eps8 binding protein e3B1 mRNA, complete cds. /FEA=mRNA /PROD=e3B1 /DB_XREF=gi:2245670 /UG=Hs.24752 spectrin SH3 domain binding protein 1 /FL=gb:AF006516.1 AF006516 abl-interactor 1 ABI1 10006 NM_001012750 /// NM_001012751 /// NM_001012752 /// NM_001178116 /// NM_001178119 /// NM_001178120 /// NM_001178121 /// NM_001178122 /// NM_001178123 /// NM_001178124 /// NM_001178125 /// NM_005470 /// XM_005252332 /// XM_005252333 /// XM_006717359 /// XM_006717360 /// XM_006717361 0001756 // somitogenesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 209029_at AF193844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF193844.1 /DEF=Homo sapiens COP9 complex subunit 7a mRNA, complete cds. /FEA=mRNA /PROD=COP9 complex subunit 7a /DB_XREF=gi:6120134 /UG=Hs.3758 COP9 complex subunit 7a /FL=gb:AB033603.1 gb:AF193844.1 gb:AF210052.1 gb:NM_016319.1 AF193844 COP9 signalosome subunit 7A COPS7A 50813 NM_001164093 /// NM_001164094 /// NM_001164095 /// NM_016319 /// XM_005253694 /// XM_005253695 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 209030_s_at NM_014333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014333.1 /DEF=Homo sapiens immunoglobulin superfamily, member 4 (IGSF4), mRNA. /FEA=CDS /GEN=IGSF4 /PROD=immunoglobulin superfamily, member 4 /DB_XREF=gi:7657225 /UG=Hs.70337 immunoglobulin superfamily, member 4 /FL=gb:NM_014333.1 gb:AF132811.1 NM_014333 cell adhesion molecule 1 CADM1 23705 NM_001098517 /// NM_014333 /// XM_005271491 /// XM_005271492 /// XM_005271493 /// XM_005271494 0001889 // liver development // inferred from electronic annotation /// 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008037 // cell recognition // inferred from direct assay /// 0008037 // cell recognition // inferred from sequence or structural similarity /// 0009826 // unidimensional cell growth // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050798 // activated T cell proliferation // inferred from direct assay /// 0051606 // detection of stimulus // inferred from direct assay /// 0051606 // detection of stimulus // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 209031_at AL519710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL519710 /FEA=EST /DB_XREF=gi:12783203 /DB_XREF=est:AL519710 /CLONE=CS0DB004YK17 (5 prime) /UG=Hs.70337 immunoglobulin superfamily, member 4 /FL=gb:NM_014333.1 gb:AF132811.1 AL519710 cell adhesion molecule 1 CADM1 23705 NM_001098517 /// NM_014333 /// XM_005271491 /// XM_005271492 /// XM_005271493 /// XM_005271494 0001889 // liver development // inferred from electronic annotation /// 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008037 // cell recognition // inferred from direct assay /// 0008037 // cell recognition // inferred from sequence or structural similarity /// 0009826 // unidimensional cell growth // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050798 // activated T cell proliferation // inferred from direct assay /// 0051606 // detection of stimulus // inferred from direct assay /// 0051606 // detection of stimulus // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 209032_s_at AF132811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF132811.1 /DEF=Homo sapiens nectin-like protein 2 (NECL2) mRNA, complete cds. /FEA=mRNA /GEN=NECL2 /PROD=nectin-like protein 2 /DB_XREF=gi:7767238 /UG=Hs.70337 immunoglobulin superfamily, member 4 /FL=gb:NM_014333.1 gb:AF132811.1 AF132811 cell adhesion molecule 1 CADM1 23705 NM_001098517 /// NM_014333 /// XM_005271491 /// XM_005271492 /// XM_005271493 /// XM_005271494 0001889 // liver development // inferred from electronic annotation /// 0001913 // T cell mediated cytotoxicity // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008037 // cell recognition // inferred from direct assay /// 0008037 // cell recognition // inferred from sequence or structural similarity /// 0009826 // unidimensional cell growth // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050798 // activated T cell proliferation // inferred from direct assay /// 0051606 // detection of stimulus // inferred from direct assay /// 0051606 // detection of stimulus // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 209033_s_at D86550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86550.1 /DEF=Human mRNA for serinethreonine protein kinase, complete cds. /FEA=mRNA /GEN=hMNB /PROD=serinethreonine protein kinase /DB_XREF=gi:1772437 /UG=Hs.75842 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A /FL=gb:D85759.1 gb:D86550.1 D86550 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DYRK1A 1859 NM_001396 /// NM_101395 /// NM_130436 /// NM_130437 /// NM_130438 /// XM_005260931 /// XM_005260933 /// XM_006723976 /// XM_006723977 /// XM_006723978 /// XM_006723979 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0090312 // positive regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043621 // protein self-association // inferred from sequence or structural similarity /// 0048156 // tau protein binding // inferred from sequence or structural similarity 209034_at AF279899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279899.1 /DEF=Homo sapiens PNAS-145 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-145 /DB_XREF=gi:12751123 /UG=Hs.75969 proline-rich protein with nuclear targeting signal /FL=gb:AF279899.1 gb:U03105.1 gb:NM_006813.1 AF279899 proline-rich nuclear receptor coactivator 1 PNRC1 10957 NM_006813 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209035_at M69148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M69148.1 /DEF=Human midkine mRNA, complete cds. /FEA=mRNA /GEN=hMK-1 /PROD=midkine /DB_XREF=gi:182650 /UG=Hs.82045 midkine (neurite growth-promoting factor 2) /FL=gb:M69148.1 gb:NM_002391.1 M69148 midkine (neurite growth-promoting factor 2) MDK 4192 NM_001012333 /// NM_001012334 /// NM_001270550 /// NM_001270551 /// NM_001270552 /// NM_002391 /// NR_073039 0001662 // behavioral fear response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007614 // short-term memory // inferred from electronic annotation /// 0009611 // response to wounding // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021681 // cerebellar granular layer development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030421 // defecation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0008083 // growth factor activity // non-traceable author statement /// 0008201 // heparin binding // inferred from direct assay 209036_s_at BC001917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001917.1 /DEF=Homo sapiens, malate dehydrogenase 2, NAD (mitochondrial), clone MGC:3559, mRNA, complete cds. /FEA=mRNA /PROD=malate dehydrogenase 2, NAD (mitochondrial) /DB_XREF=gi:12804928 /UG=Hs.111076 malate dehydrogenase 2, NAD (mitochondrial) /FL=gb:BC001917.1 gb:AF047470.1 gb:NM_005918.1 BC001917 malate dehydrogenase 2, NAD (mitochondrial) MDH2 4191 NM_001282403 /// NM_001282404 /// NM_005918 /// NR_104165 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from direct assay /// 0006108 // malate metabolic process // inferred from mutant phenotype /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030060 // L-malate dehydrogenase activity // not recorded /// 0030060 // L-malate dehydrogenase activity // inferred from direct assay /// 0030060 // L-malate dehydrogenase activity // inferred from mutant phenotype /// 0043621 // protein self-association // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046554 // malate dehydrogenase (NADP+) activity // inferred from electronic annotation 209037_s_at AW182860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW182860 /FEA=EST /DB_XREF=gi:6451320 /DB_XREF=est:xj64g08.x1 /CLONE=IMAGE:2662046 /UG=Hs.155119 EH domain containing 1 /FL=gb:AF001434.1 AW182860 EH-domain containing 1 EHD1 10938 NM_001282444 /// NM_001282445 /// NM_006795 /// XM_006718424 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0016197 // endosomal transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from physical interaction /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209038_s_at AL579035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL579035 /FEA=EST /DB_XREF=gi:12943682 /DB_XREF=est:AL579035 /CLONE=CS0DK012YB08 (3 prime) /UG=Hs.155119 EH domain containing 1 /FL=gb:AF001434.1 AL579035 EH-domain containing 1 EHD1 10938 NM_001282444 /// NM_001282445 /// NM_006795 /// XM_006718424 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0016197 // endosomal transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from physical interaction /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209039_x_at AF001434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001434.1 /DEF=Human Hpast (HPAST) mRNA, complete cds. /FEA=mRNA /GEN=HPAST /PROD=Hpast /DB_XREF=gi:2529706 /UG=Hs.155119 EH domain containing 1 /FL=gb:AF001434.1 AF001434 EH-domain containing 1 EHD1 10938 NM_001282444 /// NM_001282445 /// NM_006795 /// XM_006718424 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0016197 // endosomal transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from physical interaction /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209040_s_at U17496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17496.1 /DEF=Human proteasome subunit LMP7 (allele LMP7B) mRNA, complete cds. /FEA=mRNA /GEN=LMP7 /PROD=proteasome subunit LMP7 /DB_XREF=gi:596139 /UG=Hs.180062 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) /FL=gb:U17496.1 gb:U17497.1 U17496 proteasome (prosome, macropain) subunit, beta type, 8 PSMB8 5696 NM_004159 /// NM_148919 /// XM_005275000 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209041_s_at BG395660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG395660 /FEA=EST /DB_XREF=gi:13289108 /DB_XREF=est:602458292F1 /CLONE=IMAGE:4580782 /UG=Hs.192853 ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) /FL=gb:BC001738.1 gb:AF032456.1 gb:NM_003343.1 BG395660 ubiquitin-conjugating enzyme E2G 2 UBE2G2 7327 NM_001202489 /// NM_003343 /// NM_182688 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 209042_s_at BC001738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001738.1 /DEF=Homo sapiens, Similar to ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7), clone MGC:1589, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ubiquitin-conjugating enzyme E2G 2(homologous to yeast UBC7) /DB_XREF=gi:12804628 /UG=Hs.192853 ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) /FL=gb:BC001738.1 gb:AF032456.1 gb:NM_003343.1 BC001738 ubiquitin-conjugating enzyme E2G 2 UBE2G2 7327 NM_001202489 /// NM_003343 /// NM_182688 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 209043_at AF033026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033026.1 /DEF=Homo sapiens bifunctional ATP sulfurylaseadenosine 5-phosphosulfate kinase mRNA, complete cds. /FEA=mRNA /PROD=bifunctional ATP sulfurylaseadenosine5-phosphosulfate kinase /DB_XREF=gi:3378100 /UG=Hs.3833 3-phosphoadenosine 5-phosphosulfate synthase 1 /FL=gb:AF033026.1 gb:AF016496.1 gb:NM_005443.1 gb:AF105227.1 AF033026 3'-phosphoadenosine 5'-phosphosulfate synthase 1 PAPSS1 9061 NM_005443 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 209044_x_at BC004273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004273.1 /DEF=Homo sapiens, splicing factor 3b, subunit 4, 49kD, clone MGC:10828, mRNA, complete cds. /FEA=mRNA /PROD=splicing factor 3b, subunit 4, 49kD /DB_XREF=gi:13279088 /UG=Hs.25797 splicing factor 3b, subunit 4, 49kD /FL=gb:BC004273.1 gb:NM_005850.1 BC004273 splicing factor 3b, subunit 4, 49kDa SF3B4 10262 NM_005850 /// XM_005277331 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209045_at AF195530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF195530.1 /DEF=Homo sapiens soluble aminopeptidase P (XPNPEP1) mRNA, complete cds. /FEA=mRNA /GEN=XPNPEP1 /PROD=soluble aminopeptidase P /DB_XREF=gi:9739016 /UG=Hs.56542 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble /FL=gb:BC005126.1 gb:AF272981.1 gb:AF195530.1 AF195530 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble XPNPEP1 7511 NM_001167604 /// NM_020383 /// NR_030724 /// XM_005270144 /// XM_005270145 /// XM_006717962 /// XM_006717963 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010815 // bradykinin catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from direct assay 209046_s_at AB030710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030710.1 /DEF=Homo sapiens FLC3A mRNA for MAP1 light chain 3 related protein, complete cds. /FEA=mRNA /GEN=FLC3A /PROD=MAP1 light chain 3 related protein /DB_XREF=gi:12641848 /UG=Hs.6518 ganglioside expression factor 2 /FL=gb:AB030710.1 gb:AF087848.1 gb:AF077046.1 gb:NM_007285.1 AB030710 GABA(A) receptor-associated protein-like 2 GABARAPL2 11345 NM_007285 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006914 // autophagy // non-traceable author statement /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0032258 // CVT pathway // not recorded /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded /// 1901799 // negative regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000149 // SNARE binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // non-traceable author statement /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // non-traceable author statement /// 0051117 // ATPase binding // inferred from sequence or structural similarity 209047_at AL518391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL518391 /FEA=EST /DB_XREF=gi:12781884 /DB_XREF=est:AL518391 /CLONE=CS0DA009YJ21 (3 prime) /UG=Hs.74602 aquaporin 1 (channel-forming integral protein, 28kD) /FL=gb:M77829.1 AL518391 aquaporin 1 (Colton blood group) AQP1 358 NM_000385 /// NM_001185060 /// NM_001185061 /// NM_001185062 /// NM_198098 0003097 // renal water transport // inferred from direct assay /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from sequence or structural similarity /// 0006833 // water transport // inferred from direct assay /// 0006833 // water transport // inferred from mutant phenotype /// 0006833 // water transport // traceable author statement /// 0006884 // cell volume homeostasis // inferred from mutant phenotype /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from direct assay /// 0015701 // bicarbonate transport // traceable author statement /// 0015793 // glycerol transport // inferred from direct assay /// 0019725 // cellular homeostasis // inferred from direct assay /// 0021670 // lateral ventricle development // inferred from expression pattern /// 0030157 // pancreatic juice secretion // inferred from expression pattern /// 0030185 // nitric oxide transport // inferred from direct assay /// 0030950 // establishment or maintenance of actin cytoskeleton polarity // inferred from mutant phenotype /// 0033326 // cerebrospinal fluid secretion // inferred from expression pattern /// 0033554 // cellular response to stress // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035377 // transepithelial water transport // inferred from direct assay /// 0035378 // carbon dioxide transmembrane transport // inferred from direct assay /// 0042476 // odontogenesis // inferred from expression pattern /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046878 // positive regulation of saliva secretion // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0055085 // transmembrane transport // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071241 // cellular response to inorganic substance // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071288 // cellular response to mercury ion // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071472 // cellular response to salt stress // inferred from direct assay /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 0071549 // cellular response to dexamethasone stimulus // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype /// 0071805 // potassium ion transmembrane transport // inferred from sequence or structural similarity /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0085018 // maintenance of symbiont-containing vacuole by host // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0020003 // symbiont-containing vacuole // inferred from sequence or structural similarity /// 0020005 // symbiont-containing vacuole membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from mutant phenotype /// 0005372 // water transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0015079 // potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015168 // glycerol transmembrane transporter activity // inferred from direct assay /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // inferred from direct assay /// 0015250 // water channel activity // inferred from mutant phenotype /// 0022857 // transmembrane transporter activity // inferred from direct assay /// 0030184 // nitric oxide transmembrane transporter activity // inferred from direct assay /// 0035379 // carbon dioxide transmembrane transporter activity // inferred from direct assay /// 0035379 // carbon dioxide transmembrane transporter activity // traceable author statement 209048_s_at AB032951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032951.1 /DEF=Homo sapiens mRNA for KIAA1125 protein, partial cds. /FEA=mRNA /GEN=KIAA1125 /PROD=KIAA1125 protein /DB_XREF=gi:6329748 /UG=Hs.75871 protein kinase C binding protein 1 /FL=gb:BC001004.1 AB032951 zinc finger, MYND-type containing 8 ZMYND8 23613 NM_001281769 /// NM_001281771 /// NM_001281772 /// NM_001281773 /// NM_001281774 /// NM_001281775 /// NM_001281776 /// NM_001281777 /// NM_001281778 /// NM_001281779 /// NM_001281780 /// NM_001281781 /// NM_001281782 /// NM_001281783 /// NM_001281784 /// NM_012408 /// NM_183047 /// NM_183048 /// XM_005260356 /// XM_005260358 /// XM_005260360 /// XM_005260361 /// XM_005260362 /// XM_005260364 /// XM_005260365 /// XM_005260366 /// XM_005260369 /// XM_005260371 /// XM_005260377 /// XM_006723760 /// XM_006723761 /// XM_006723762 /// XM_006723763 /// XM_006723764 /// XM_006723765 /// XM_006723766 /// XM_006723767 /// XM_006723768 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity 209049_s_at BC001004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001004.1 /DEF=Homo sapiens, clone MGC:5439, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5439) /DB_XREF=gi:12654362 /UG=Hs.75871 protein kinase C binding protein 1 /FL=gb:BC001004.1 BC001004 zinc finger, MYND-type containing 8 ZMYND8 23613 NM_001281769 /// NM_001281771 /// NM_001281772 /// NM_001281773 /// NM_001281774 /// NM_001281775 /// NM_001281776 /// NM_001281777 /// NM_001281778 /// NM_001281779 /// NM_001281780 /// NM_001281781 /// NM_001281782 /// NM_001281783 /// NM_001281784 /// NM_012408 /// NM_183047 /// NM_183048 /// XM_005260356 /// XM_005260358 /// XM_005260360 /// XM_005260361 /// XM_005260362 /// XM_005260364 /// XM_005260365 /// XM_005260366 /// XM_005260369 /// XM_005260371 /// XM_005260377 /// XM_006723760 /// XM_006723761 /// XM_006723762 /// XM_006723763 /// XM_006723764 /// XM_006723765 /// XM_006723766 /// XM_006723767 /// XM_006723768 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity 209050_s_at AI421559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI421559 /FEA=EST /DB_XREF=gi:4267490 /DB_XREF=est:tf15e03.x1 /CLONE=IMAGE:2096284 /UG=Hs.106185 ral guanine nucleotide dissociation stimulator /FL=gb:AF295773.1 AI421559 ral guanine nucleotide dissociation stimulator RALGDS 5900 NM_001042368 /// NM_001271774 /// NM_001271775 /// NM_001271776 /// NM_006266 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005083 // small GTPase regulator activity // inferred from direct assay /// 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209051_s_at AF295773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF295773.1 /DEF=Homo sapiens ral guanine nucleotide dissociation stimulator (RALGDS) mRNA, complete cds. /FEA=mRNA /GEN=RALGDS /PROD=ral guanine nucleotide dissociation stimulator /DB_XREF=gi:9931301 /UG=Hs.106185 ral guanine nucleotide dissociation stimulator /FL=gb:AF295773.1 AF295773 ral guanine nucleotide dissociation stimulator RALGDS 5900 NM_001042368 /// NM_001271774 /// NM_001271775 /// NM_001271776 /// NM_006266 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005083 // small GTPase regulator activity // inferred from direct assay /// 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209052_s_at BF111870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF111870 /FEA=EST /DB_XREF=gi:10941560 /DB_XREF=est:7l36f11.x1 /CLONE=IMAGE:3523724 /UG=Hs.110457 Wolf-Hirschhorn syndrome candidate 1 /FL=gb:AF083389.1 BF111870 Wolf-Hirschhorn syndrome candidate 1 WHSC1 7468 NM_001042424 /// NM_007331 /// NM_014919 /// NM_133330 /// NM_133331 /// NM_133332 /// NM_133333 /// NM_133334 /// NM_133335 /// NM_133336 /// XM_005248001 /// XM_005248002 /// XM_005248005 /// XM_006713914 /// XM_006713915 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003289 // atrial septum primum morphogenesis // inferred from electronic annotation /// 0003290 // atrial septum secundum morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209053_s_at BE793789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE793789 /FEA=EST /DB_XREF=gi:10214987 /DB_XREF=est:601589946F1 /CLONE=IMAGE:3944195 /UG=Hs.110457 Wolf-Hirschhorn syndrome candidate 1 /FL=gb:AF083389.1 BE793789 Wolf-Hirschhorn syndrome candidate 1 WHSC1 7468 NM_001042424 /// NM_007331 /// NM_014919 /// NM_133330 /// NM_133331 /// NM_133332 /// NM_133333 /// NM_133334 /// NM_133335 /// NM_133336 /// XM_005248001 /// XM_005248002 /// XM_005248005 /// XM_006713914 /// XM_006713915 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003289 // atrial septum primum morphogenesis // inferred from electronic annotation /// 0003290 // atrial septum secundum morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209054_s_at AF083389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083389.1 /DEF=Homo sapiens putative WHSC1 protein (WHSC1) mRNA, alternative splice product with complete exon 12, complete cds. /FEA=mRNA /GEN=WHSC1 /PROD=putative WHSC1 protein /DB_XREF=gi:4378016 /UG=Hs.110457 Wolf-Hirschhorn syndrome candidate 1 /FL=gb:AF083389.1 AF083389 Wolf-Hirschhorn syndrome candidate 1 WHSC1 7468 NM_001042424 /// NM_007331 /// NM_014919 /// NM_133330 /// NM_133331 /// NM_133332 /// NM_133333 /// NM_133334 /// NM_133335 /// NM_133336 /// XM_005248001 /// XM_005248002 /// XM_005248005 /// XM_006713914 /// XM_006713915 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003289 // atrial septum primum morphogenesis // inferred from electronic annotation /// 0003290 // atrial septum secundum morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209055_s_at AW268817 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW268817 /FEA=EST /DB_XREF=gi:6655847 /DB_XREF=est:xv38c01.x1 /CLONE=IMAGE:2815392 /UG=Hs.155174 CDC5 (cell division cycle 5, S. pombe, homolog)-like /FL=gb:NM_001253.1 gb:U86753.1 gb:AB007892.1 AW268817 cell division cycle 5-like CDC5L 988 NM_001253 /// XM_006715289 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071987 // WD40-repeat domain binding // inferred from direct assay 209056_s_at NM_001253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001253.1 /DEF=Homo sapiens CDC5 (cell division cycle 5, S. pombe, homolog)-like (CDC5L), mRNA. /FEA=CDS /GEN=CDC5L /PROD=CDC5 (cell division cycle 5, S. pombe,homolog)-like /DB_XREF=gi:11067746 /UG=Hs.155174 CDC5 (cell division cycle 5, S. pombe, homolog)-like /FL=gb:NM_001253.1 gb:U86753.1 gb:AB007892.1 NM_001253 cell division cycle 5-like CDC5L 988 NM_001253 /// XM_006715289 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071987 // WD40-repeat domain binding // inferred from direct assay 209057_x_at AB007892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007892.1 /DEF=Homo sapiens KIAA0432 mRNA, complete cds. /FEA=mRNA /GEN=KIAA0432 /DB_XREF=gi:2887434 /UG=Hs.155174 CDC5 (cell division cycle 5, S. pombe, homolog)-like /FL=gb:NM_001253.1 gb:U86753.1 gb:AB007892.1 AB007892 cell division cycle 5-like CDC5L 988 NM_001253 /// XM_006715289 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071987 // WD40-repeat domain binding // inferred from direct assay 209058_at AB002282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002282.1 /DEF=Homo sapiens mRNA for hMBF1alpha, complete cds. /FEA=mRNA /PROD=hMBF1alpha /DB_XREF=gi:6526354 /UG=Hs.174050 endothelial differentiation-related factor 1 /FL=gb:NM_003792.1 gb:AB002282.1 AB002282 endothelial differentiation-related factor 1 EDF1 8721 NM_001281297 /// NM_001281298 /// NM_001281299 /// NM_003792 /// NM_153200 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045446 // endothelial cell differentiation // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // non-traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209059_s_at AB002282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002282.1 /DEF=Homo sapiens mRNA for hMBF1alpha, complete cds. /FEA=mRNA /PROD=hMBF1alpha /DB_XREF=gi:6526354 /UG=Hs.174050 endothelial differentiation-related factor 1 /FL=gb:NM_003792.1 gb:AB002282.1 AB002282 endothelial differentiation-related factor 1 EDF1 8721 NM_001281297 /// NM_001281298 /// NM_001281299 /// NM_003792 /// NM_153200 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045446 // endothelial cell differentiation // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // non-traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209060_x_at AI438999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI438999 /FEA=EST /DB_XREF=gi:4301251 /DB_XREF=est:tc84b12.x1 /CLONE=IMAGE:2072831 /UG=Hs.225977 nuclear receptor coactivator 3 /FL=gb:AF010227.1 gb:AF012108.1 gb:AF016031.1 AI438999 nuclear receptor coactivator 3 NCOA3 8202 NM_001174087 /// NM_001174088 /// NM_006534 /// NM_181659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035624 // receptor transactivation // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 209061_at AI761748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761748 /FEA=EST /DB_XREF=gi:5177504 /DB_XREF=est:wg67h01.x1 /CLONE=IMAGE:2370193 /UG=Hs.225977 nuclear receptor coactivator 3 /FL=gb:AF010227.1 gb:AF012108.1 gb:AF016031.1 AI761748 nuclear receptor coactivator 3 NCOA3 8202 NM_001174087 /// NM_001174088 /// NM_006534 /// NM_181659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035624 // receptor transactivation // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 209062_x_at AF010227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010227.1 /DEF=Homo sapiens receptor-associated coactivator 3 (RAC3) mRNA, complete cds. /FEA=mRNA /GEN=RAC3 /PROD=receptor-associated coactivator 3 /DB_XREF=gi:2318005 /UG=Hs.225977 nuclear receptor coactivator 3 /FL=gb:AF010227.1 gb:AF012108.1 gb:AF016031.1 AF010227 nuclear receptor coactivator 3 NCOA3 8202 NM_001174087 /// NM_001174088 /// NM_006534 /// NM_181659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035624 // receptor transactivation // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 209063_x_at BF248165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF248165 /FEA=EST /DB_XREF=gi:11164389 /DB_XREF=est:601859364F1 /CLONE=IMAGE:4069886 /UG=Hs.109643 polyadenylate binding protein-interacting protein 1 /FL=gb:AL136920.1 BF248165 poly(A) binding protein interacting protein 1 PAIP1 10605 NM_006451 /// NM_182789 /// NM_183323 /// XM_005248230 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 209064_x_at AL136920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136920.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C051 (from clone DKFZp586C051); complete cds. /FEA=mRNA /GEN=DKFZp586C051 /PROD=hypothetical protein /DB_XREF=gi:12053334 /UG=Hs.109643 polyadenylate binding protein-interacting protein 1 /FL=gb:AL136920.1 AL136920 poly(A) binding protein interacting protein 1 PAIP1 10605 NM_006451 /// NM_182789 /// NM_183323 /// XM_005248230 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 209065_at BC005230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005230.1 /DEF=Homo sapiens, ubiquinol-cytochrome c reductase binding protein, clone MGC:12253, mRNA, complete cds. /FEA=mRNA /PROD=ubiquinol-cytochrome c reductase bindingprotein /DB_XREF=gi:13528857 /UG=Hs.131255 ubiquinol-cytochrome c reductase binding protein /FL=gb:BC005230.1 gb:M26700.1 BC005230 ubiquinol-cytochrome c reductase binding protein UQCRB 7381 NM_001199975 /// NM_001254752 /// NM_006294 /// NR_045639 /// XM_006716652 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 209066_x_at M26700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M26700.1 /DEF=Human mitochondrial ubiquinone-binding protein mRNA, complete cds. /FEA=mRNA /GEN=UQBP /DB_XREF=gi:190803 /UG=Hs.131255 ubiquinol-cytochrome c reductase binding protein /FL=gb:BC005230.1 gb:M26700.1 M26700 ubiquinol-cytochrome c reductase binding protein UQCRB 7381 NM_001199975 /// NM_001254752 /// NM_006294 /// NR_045639 /// XM_006716652 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 209067_s_at D89092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89092.1 /DEF=Homo sapiens hnRNP JKTBP mRNA, complete cds. /FEA=mRNA /GEN=hnRNP JKTBP /DB_XREF=gi:2780747 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like /FL=gb:D89092.1 gb:D89678.1 D89092 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209068_at D89678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89678.1 /DEF=Homo sapiens mRNA for A+U-rich element RNA binding factor, complete cds. /FEA=mRNA /PROD=A+U-rich element RNA binding factor /DB_XREF=gi:3218539 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like /FL=gb:D89092.1 gb:D89678.1 D89678 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209069_s_at BC001124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001124.1 /DEF=Homo sapiens, H3 histone, family 3A, clone MGC:2161, mRNA, complete cds. /FEA=mRNA /PROD=H3 histone, family 3A /DB_XREF=gi:12654576 /UG=Hs.181307 H3 histone, family 3A /FL=gb:BC001124.1 BC001124 H3 histone, family 3A /// H3 histone, family 3B (H3.3B) /// microRNA 4738 H3F3A /// H3F3B /// MIR4738 3020 /// 3021 /// 100616282 NM_002107 /// NM_005324 /// NR_039892 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209070_s_at AI183997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI183997 /FEA=EST /DB_XREF=gi:3734635 /DB_XREF=est:qd69h09.x1 /CLONE=IMAGE:1734785 /UG=Hs.24950 regulator of G-protein signalling 5 /FL=gb:AB008109.1 gb:NM_003617.1 gb:AF159570.1 AI183997 regulator of G-protein signaling 5 RGS5 8490 NM_001195303 /// NM_001254748 /// NM_001254749 /// NM_003617 /// NM_025226 /// NR_045630 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded 209071_s_at AF159570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF159570.1 /DEF=Homo sapiens regulator of G-protein signalling 5 (RGS5) mRNA, complete cds. /FEA=mRNA /GEN=RGS5 /PROD=regulator of G-protein signalling 5 /DB_XREF=gi:5230675 /UG=Hs.24950 regulator of G-protein signalling 5 /FL=gb:AB008109.1 gb:NM_003617.1 gb:AF159570.1 AF159570 regulator of G-protein signaling 5 RGS5 8490 NM_001195303 /// NM_001254748 /// NM_001254749 /// NM_003617 /// NM_025226 /// NR_045630 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded 209072_at M13577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13577.1 /DEF=Human myelin basic protein (MBP) mRNA, complete cds. /FEA=mRNA /GEN=MBP /DB_XREF=gi:187408 /UG=Hs.69547 myelin basic protein /FL=gb:M13577.1 M13577 myelin basic protein MBP 4155 NM_001025081 /// NM_001025090 /// NM_001025092 /// NM_001025094 /// NM_001025098 /// NM_001025100 /// NM_001025101 /// NM_002385 /// XM_005266699 /// XR_245459 /// XR_245460 /// XR_245461 /// XR_430073 /// XR_430074 0006955 // immune response // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008366 // axon ensheathment // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042552 // myelination // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0061024 // membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033269 // internode region of axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 209073_s_at AF015040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015040.1 /DEF=Homo sapiens NUMB protein (NUMB) mRNA, complete cds. /FEA=mRNA /GEN=NUMB /PROD=NUMB protein /DB_XREF=gi:4102704 /UG=Hs.78890 numb (Drosophila) homolog /FL=gb:AF015040.1 gb:AF108092.1 gb:AF171939.1 AF015040 uncharacterized LOC101928143 /// uncharacterized LOC101930388 /// numb homolog (Drosophila) LOC101928143 /// LOC101930388 /// NUMB 8650 /// 101928143 /// 101930388 NM_001005743 /// NM_001005744 /// NM_001005745 /// NM_003744 /// XM_005268142 /// XM_005268143 /// XM_005268144 /// XM_005268145 /// XM_005268146 /// XM_006720283 /// XM_006720284 /// XM_006720285 /// XM_006720286 /// XM_006720287 /// XM_006720288 /// XM_006720289 /// XM_006720290 /// XM_006720291 /// XM_006720292 /// XM_006720293 /// XM_006720294 /// XM_006720295 /// XM_006720296 /// XR_245781 /// XR_245782 /// XR_245783 /// XR_245784 /// XR_248038 /// XR_248039 /// XR_248040 /// XR_248041 /// XR_248042 /// XR_253273 /// XR_253274 /// XR_253275 /// XR_253276 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0021670 // lateral ventricle development // inferred from sequence or structural similarity /// 0021849 // neuroblast division in subventricular zone // inferred from sequence or structural similarity /// 0030862 // positive regulation of polarized epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 209074_s_at AL050264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL050264.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564N0582 (from clone DKFZp564N0582); complete cds. /FEA=mRNA /GEN=DKFZp564N0582 /PROD=hypothetical protein /DB_XREF=gi:4886486 /UG=Hs.8022 TU3A protein /FL=gb:AF089853.1 gb:AL050264.1 gb:AB023811.1 AL050264 family with sequence similarity 107, member A FAM107A 11170 NM_001076778 /// NM_001282713 /// NM_001282714 /// NM_007177 /// XM_005264835 0001558 // regulation of cell growth // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 209075_s_at AY009128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY009128.1 /DEF=Homo sapiens ISCU2 (ISCU) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=ISCU /PROD=ISCU2 /DB_XREF=gi:11545706 /UG=Hs.9908 nitrogen fixation cluster-like /FL=gb:AY009128.1 AY009128 iron-sulfur cluster assembly enzyme ISCU 23479 NM_014301 /// NM_213595 /// XM_005268760 /// XM_005268761 /// XM_006719315 /// XM_006719316 /// XR_429087 0009399 // nitrogen fixation // traceable author statement /// 0016226 // iron-sulfur cluster assembly // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 209076_s_at BC000974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000974.2 /DEF=Homo sapiens, Similar to hypothetical protein 628, clone MGC:5116, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein 628 /DB_XREF=gi:12803025 /UG=Hs.181349 hypothetical protein 628 /FL=gb:BC000974.2 BC000974 WD repeat domain 45B WDR45B 56270 NM_019613 /// XM_005256377 /// XM_005256378 /// XM_006722285 /// XR_243524 0000045 // autophagic vacuole assembly // not recorded 0005737 // cytoplasm // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // not recorded /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // not recorded 209077_at AL022313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022313 /DEF=Human DNA sequence from clone RP5-1119A7 on chromosome 22q12.2-12.3 Contains the TXN2 gene for mitochondrial thioredoxin, a novel gene, the EIF3S7 gene for eukaryotic translation initiation factor 3 subunit 7 (zeta, 6667kD) (EIF3-P66), the gene f... /FEA=mRNA_4 /DB_XREF=gi:4200326 /UG=Hs.211929 thioredoxin, mitochondrial /FL=gb:U78678.1 gb:NM_012473.1 gb:AF276920.1 AL022313 thioredoxin 2 TXN2 25828 NM_012473 /// XM_005261508 /// XM_006724226 0001666 // response to hypoxia // inferred from electronic annotation /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 209078_s_at AF276920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF276920.1 /DEF=Homo sapiens thioredoxin 2 (TRX2) mRNA, complete cds. /FEA=mRNA /GEN=TRX2 /PROD=thioredoxin 2 /DB_XREF=gi:9280552 /UG=Hs.211929 thioredoxin, mitochondrial /FL=gb:U78678.1 gb:NM_012473.1 gb:AF276920.1 AF276920 thioredoxin 2 TXN2 25828 NM_012473 /// XM_005261508 /// XM_006724226 0001666 // response to hypoxia // inferred from electronic annotation /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 209079_x_at AF152318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152318.1 /DEF=Homo sapiens protocadherin gamma A1 (PCDH-gamma-A1) mRNA, complete cds. /FEA=mRNA /GEN=PCDH-gamma-A1 /PROD=protocadherin gamma A1 /DB_XREF=gi:5456923 /UG=Hs.284180 protocadherin gamma subfamily A, 1 /FL=gb:NM_018912.1 gb:BC004321.1 gb:AF152318.1 AF152318 protocadherin gamma subfamily A, 1 /// protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 2 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 4 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily A, 7 /// protocadherin gamma subfamily A, 8 /// protocadherin gamma subfamily A, 9 /// protocadherin gamma subfamily B, 1 /// protocadherin gamma subfamily B, 2 /// protocadherin gamma subfamily B, 3 /// protocadherin gamma subfamily B, 4 /// protocadherin gamma subfamily B, 5 /// protocadherin gamma subfamily B, 6 /// protocadherin gamma subfamily B, 7 /// protocadherin gamma subfamily C, 3 /// protocadherin gamma subfamily C, 4 /// protocadherin gamma subfamily C, 5 PCDHGA1 /// PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA2 /// PCDHGA3 /// PCDHGA4 /// PCDHGA5 /// PCDHGA6 /// PCDHGA7 /// PCDHGA8 /// PCDHGA9 /// PCDHGB1 /// PCDHGB2 /// PCDHGB3 /// PCDHGB4 /// PCDHGB5 /// PCDHGB6 /// PCDHGB7 /// PCDHGC3 /// PCDHGC4 /// PCDHGC5 5098 /// 8641 /// 9708 /// 26025 /// 56097 /// 56098 /// 56099 /// 56100 /// 56101 /// 56102 /// 56103 /// 56104 /// 56105 /// 56106 /// 56107 /// 56108 /// 56109 /// 56110 /// 56111 /// 56112 /// 56113 /// 56114 NM_002588 /// NM_003735 /// NM_003736 /// NM_014004 /// NM_018912 /// NM_018913 /// NM_018914 /// NM_018915 /// NM_018916 /// NM_018917 /// NM_018918 /// NM_018919 /// NM_018920 /// NM_018921 /// NM_018922 /// NM_018923 /// NM_018924 /// NM_018925 /// NM_018926 /// NM_018927 /// NM_018928 /// NM_018929 /// NM_031993 /// NM_032009 /// NM_032011 /// NM_032053 /// NM_032054 /// NM_032086 /// NM_032087 /// NM_032088 /// NM_032089 /// NM_032090 /// NM_032091 /// NM_032092 /// NM_032094 /// NM_032095 /// NM_032096 /// NM_032097 /// NM_032098 /// NM_032099 /// NM_032100 /// NM_032101 /// NM_032402 /// NM_032403 /// NM_032406 /// NM_032407 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209080_x_at AF118652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118652.1 /DEF=Homo sapiens PKCq-interacting protein PICOT (PICOT) mRNA, complete cds. /FEA=mRNA /GEN=PICOT /PROD=PKCq-interacting protein PICOT /DB_XREF=gi:6840952 /UG=Hs.42644 thioredoxin-like /FL=gb:BC005289.1 gb:AF118649.1 gb:AF118652.1 AF118652 glutaredoxin 3 GLRX3 10539 NM_001199868 /// NM_006541 /// XM_005252657 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 209081_s_at NM_030582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_030582.1 /DEF=Homo sapiens collagen, type XVIII, alpha 1 (COL18A1), mRNA. /FEA=CDS /GEN=COL18A1 /PROD=collagen, type XVIII, alpha 1 /DB_XREF=gi:13385619 /UG=Hs.78409 collagen, type XVIII, alpha 1 /FL=gb:NM_030582.1 gb:AF018081.1 gb:AF184060.1 gb:NM_016214.1 NM_030582 collagen, type XVIII, alpha 1 COL18A1 80781 NM_030582 /// NM_130444 /// NM_130445 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051599 // response to hydrostatic pressure // inferred from electronic annotation /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209082_s_at AF018081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF018081.1 /DEF=Homo sapiens type XVIII collagen (COL18A1) mRNA, alternatively spliced, long form, complete cds. /FEA=mRNA /GEN=COL18A1 /PROD=type XVIII collagen /DB_XREF=gi:2920534 /UG=Hs.78409 collagen, type XVIII, alpha 1 /FL=gb:NM_030582.1 gb:AF018081.1 gb:AF184060.1 gb:NM_016214.1 AF018081 collagen, type XVIII, alpha 1 COL18A1 80781 NM_030582 /// NM_130444 /// NM_130445 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051599 // response to hydrostatic pressure // inferred from electronic annotation /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209083_at U34690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34690.1 /DEF=Human coronin-like protein (HCORO1) mRNA, complete cds. /FEA=mRNA /GEN=HCORO1 /PROD=coronin-like protein /DB_XREF=gi:1002922 /UG=Hs.109606 coronin, actin-binding protein, 1A /FL=gb:U34690.1 gb:NM_007074.1 gb:D44497.1 U34690 coronin, actin binding protein, 1A CORO1A 11151 NM_001193333 /// NM_007074 0001845 // phagolysosome assembly // inferred from mutant phenotype /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from mutant phenotype /// 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // inferred from electronic annotation /// 0008360 // regulation of cell shape // not recorded /// 0016477 // cell migration // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // not recorded /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032796 // uropod organization // not recorded /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // non-traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0001772 // immunological synapse // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 209084_s_at BE504689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE504689 /FEA=EST /DB_XREF=gi:9707097 /DB_XREF=est:hz30h07.x1 /CLONE=IMAGE:3209533 /UG=Hs.166563 replication factor C (activator 1) 1 (145kD) /FL=gb:AF040250.1 gb:L14922.1 BE504689 RAB28, member RAS oncogene family RAB28 9364 NM_001017979 /// NM_001159601 /// NM_004249 /// XM_005248215 /// XM_005248217 /// XM_005248218 /// XM_006713987 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // /// 0003677 // DNA binding // inferred from electronic annotation /// 0003689 // DNA clamp loader activity // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209085_x_at L14922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14922.1 /DEF=Homo sapiens DNA-binding protein (PO-GA) mRNA, complete cds. /FEA=mRNA /PROD=DNA-binding protein /DB_XREF=gi:307337 /UG=Hs.166563 replication factor C (activator 1) 1 (145kD) /FL=gb:AF040250.1 gb:L14922.1 L14922 replication factor C (activator 1) 1, 145kDa RFC1 5981 NM_001204747 /// NM_002913 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // not recorded /// 0003689 // DNA clamp loader activity // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209086_x_at BE964361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964361 /FEA=EST /DB_XREF=gi:11767830 /DB_XREF=est:601658062R1 /CLONE=IMAGE:3876255 /UG=Hs.211579 melanoma adhesion molecule /FL=gb:AF089868.1 gb:NM_006500.1 BE964361 melanoma cell adhesion molecule /// microRNA 6756 MCAM /// MIR6756 4162 /// 102465453 NM_006500 /// NR_106814 /// XM_005271551 /// XM_005271552 /// XM_006718836 /// XM_006718837 /// XM_006718838 0003094 // glomerular filtration // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0061042 // vascular wound healing // inferred from expression pattern 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209087_x_at AF089868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF089868.1 /DEF=Homo sapiens cell surface glycoprotein P1H12 precursor, mRNA, complete cds. /FEA=mRNA /PROD=cell surface glycoprotein P1H12 precursor /DB_XREF=gi:4336423 /UG=Hs.211579 melanoma adhesion molecule /FL=gb:AF089868.1 gb:NM_006500.1 AF089868 melanoma cell adhesion molecule MCAM 4162 NM_006500 /// XM_005271551 /// XM_005271552 /// XM_006718836 /// XM_006718837 /// XM_006718838 0003094 // glomerular filtration // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0061042 // vascular wound healing // inferred from expression pattern 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 209088_s_at T70262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T70262 /FEA=EST /DB_XREF=gi:681410 /DB_XREF=est:yd26b11.s1 /CLONE=IMAGE:109341 /UG=Hs.21479 ubinuclein 1 /FL=gb:AF108461.1 T70262 ubinuclein 1 UBN1 29855 NM_001079514 /// NM_001288656 /// NM_016936 /// XM_005255277 /// XM_005255278 /// XM_005255279 /// XM_005255280 /// XM_005255283 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209089_at BC001267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001267.1 /DEF=Homo sapiens, RAB5A, member RAS oncogene family, clone MGC:5048, mRNA, complete cds. /FEA=mRNA /PROD=RAB5A, member RAS oncogene family /DB_XREF=gi:12654846 /UG=Hs.73957 RAB5A, member RAS oncogene family /FL=gb:BC001267.1 BC001267 RAB5A, member RAS oncogene family RAB5A 5868 NM_001292048 /// NM_004162 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 209090_s_at AL049597 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049597 /DEF=Human DNA sequence from clone RP4-612B15 on chromosome 1p22.2-31.1. Contains the (possibly pseudo) gene for a novel protein similar to 60S ribosomal protein L17 (RPL17), the gene for CGI-61, endophilin B1 and KIAA0491, ESTs, STSs, GSSs and two CpG... /FEA=mRNA_3 /DB_XREF=gi:9663352 /UG=Hs.136309 SH3-containing protein SH3GLB1 /FL=gb:AF263293.1 AL049597 SH3-domain GRB2-like endophilin B1 SH3GLB1 51100 NM_001206651 /// NM_001206652 /// NM_001206653 /// NM_016009 /// XM_006710672 /// XM_006710673 0006654 // phosphatidic acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005504 // fatty acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 209091_s_at AF263293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF263293.1 /DEF=Homo sapiens endophilin B1 mRNA, complete cds. /FEA=mRNA /PROD=endophilin B1 /DB_XREF=gi:8118529 /UG=Hs.136309 SH3-containing protein SH3GLB1 /FL=gb:AF263293.1 AF263293 SH3-domain GRB2-like endophilin B1 SH3GLB1 51100 NM_001206651 /// NM_001206652 /// NM_001206653 /// NM_016009 /// XM_006710672 /// XM_006710673 0006654 // phosphatidic acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005504 // fatty acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 209092_s_at AF061730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061730.1 /DEF=Homo sapiens clone 016b03 My027 protein mRNA, complete cds. /FEA=mRNA /PROD=My027 protein /DB_XREF=gi:12001995 /UG=Hs.279061 CGI-150 protein /FL=gb:AF061730.1 gb:AF151908.1 gb:NM_016080.1 AF061730 glyoxalase domain containing 4 GLOD4 51031 NM_016080 /// XM_006721540 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 209093_s_at K02920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K02920.1 /DEF=Human lysosomal glucocerebrosidase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183021 /UG=Hs.282997 glucosidase, beta; acid (includes glucosylceramidase) /FL=gb:BC003356.1 gb:M16328.1 gb:K02920.1 gb:M19285.1 gb:NM_000157.1 gb:D13286.1 K02920 glucosidase, beta, acid /// glucosidase, beta, acid pseudogene 1 GBA /// GBAP1 2629 /// 2630 NM_000157 /// NM_001005741 /// NM_001005742 /// NM_001005749 /// NM_001005750 /// NM_001171811 /// NM_001171812 /// NR_002188 /// XM_006711270 /// XM_006726211 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006680 // glucosylceramide catabolic process // inferred from mutant phenotype /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046512 // sphingosine biosynthetic process // inferred from mutant phenotype /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004348 // glucosylceramidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 209094_at AL078459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078459 /DEF=Human DNA sequence from clone RP4-621F18 on chromosome 1p11.4-21.3. Contains the 3 end of the gene for ng,ng dimethylarginine dimethylaminohydrolase (EC 3.5.3.18), ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:5791502 /UG=Hs.303180 dimethylarginine dimethylaminohydrolase 1 /FL=gb:AB001915.1 gb:NM_012137.1 AL078459 dimethylarginine dimethylaminohydrolase 1 DDAH1 23576 NM_001134445 /// NM_012137 /// XM_005270706 /// XM_005270707 /// XM_005270708 /// XM_005270709 /// XM_005270710 /// XM_006710543 /// XM_006710544 0000052 // citrulline metabolic process // inferred from direct assay /// 0003073 // regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0016403 // dimethylargininase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209095_at J03620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03620.1 /DEF=Human dihydrolipoamide dehydrogenase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181574 /UG=Hs.74635 dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) /FL=gb:J03620.1 gb:J03490.1 gb:NM_000108.2 J03620 dihydrolipoamide dehydrogenase DLD 1738 NM_000108 /// NM_001289750 /// NM_001289751 /// NM_001289752 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006554 // lysine catabolic process // traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0043159 // acrosomal matrix // inferred from electronic annotation 0004148 // dihydrolipoyl dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 209096_at U62136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62136.2 /DEF=Homo sapiens enterocyte differentiation associated factor EDAF-1 mRNA, complete cds. /FEA=mRNA /PROD=enterocyte differentiation associated factorEDAF-1 /DB_XREF=gi:4775663 /UG=Hs.79300 ubiquitin-conjugating enzyme E2 variant 2 /FL=gb:NM_003350.2 gb:AF049140.1 gb:U62136.2 U62136 ubiquitin-conjugating enzyme E2 variant 2 UBE2V2 7336 NM_003350 /// XM_005251300 0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0006282 // regulation of DNA repair // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0042275 // error-free postreplication DNA repair // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 209097_s_at BF056748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056748 /FEA=EST /DB_XREF=gi:10810644 /DB_XREF=est:7k20h10.x1 /CLONE=IMAGE:3476203 /UG=Hs.91143 jagged 1 (Alagille syndrome) /FL=gb:U61276.1 gb:U73936.1 gb:AF003837.1 gb:AF028593.1 gb:NM_000214.1 BF056748 jagged 1 JAG1 182 NM_000214 0001525 // angiogenesis // non-traceable author statement /// 0001709 // cell fate determination // non-traceable author statement /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0030334 // regulation of cell migration // non-traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // non-traceable author statement /// 0045446 // endothelial cell differentiation // non-traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045639 // positive regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from mutant phenotype /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0061314 // Notch signaling involved in heart development // inferred from mutant phenotype /// 0061444 // endocardial cushion cell development // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from electronic annotation /// 0072070 // loop of Henle development // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005112 // Notch binding // non-traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 209098_s_at U61276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U61276.1 /DEF=Human transmembrane protein Jagged 1 (HJ1) mRNA, complete cds. /FEA=mRNA /GEN=HJ1 /PROD=transmembrane protein Jagged 1 /DB_XREF=gi:1438936 /UG=Hs.91143 jagged 1 (Alagille syndrome) /FL=gb:U61276.1 gb:U73936.1 gb:AF003837.1 gb:AF028593.1 gb:NM_000214.1 U61276 jagged 1 JAG1 182 NM_000214 0001525 // angiogenesis // non-traceable author statement /// 0001709 // cell fate determination // non-traceable author statement /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0030334 // regulation of cell migration // non-traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // non-traceable author statement /// 0045446 // endothelial cell differentiation // non-traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045639 // positive regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from mutant phenotype /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0061314 // Notch signaling involved in heart development // inferred from mutant phenotype /// 0061444 // endocardial cushion cell development // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from electronic annotation /// 0072070 // loop of Henle development // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005112 // Notch binding // non-traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 209099_x_at U73936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73936.1 /DEF=Homo sapiens Jagged 1 (HJ1) mRNA, complete cds. /FEA=mRNA /GEN=HJ1 /PROD=Jagged 1 /DB_XREF=gi:1695273 /UG=Hs.91143 jagged 1 (Alagille syndrome) /FL=gb:U61276.1 gb:U73936.1 gb:AF003837.1 gb:AF028593.1 gb:NM_000214.1 U73936 jagged 1 JAG1 182 NM_000214 0001525 // angiogenesis // non-traceable author statement /// 0001709 // cell fate determination // non-traceable author statement /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0030334 // regulation of cell migration // non-traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // non-traceable author statement /// 0045446 // endothelial cell differentiation // non-traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045639 // positive regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from mutant phenotype /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0061314 // Notch signaling involved in heart development // inferred from mutant phenotype /// 0061444 // endocardial cushion cell development // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from electronic annotation /// 0072070 // loop of Henle development // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005112 // Notch binding // non-traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 209100_at BC001327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001327.1 /DEF=Homo sapiens, interferon-related developmental regulator 2, clone MGC:5552, mRNA, complete cds. /FEA=mRNA /PROD=interferon-related developmental regulator 2 /DB_XREF=gi:12654958 /UG=Hs.315177 interferon-related developmental regulator 2 /FL=gb:BC001327.1 gb:BC001676.1 gb:NM_006764.1 BC001327 interferon-related developmental regulator 2 IFRD2 7866 NM_006764 0005634 // nucleus // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209101_at M92934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M92934.1 /DEF=Human connective tissue growth factor, complete cds. /FEA=mRNA /PROD=connective tissue growth factor /DB_XREF=gi:180923 /UG=Hs.75511 connective tissue growth factor /FL=gb:M92934.1 gb:NM_001901.1 M92934 connective tissue growth factor CTGF 1490 NM_001901 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010260 // organ senescence // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0034059 // response to anoxia // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050867 // positive regulation of cell activation // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0060401 // cytosolic calcium ion transport // inferred from electronic annotation /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001968 // fibronectin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 209102_s_at AF019214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF019214.1 /DEF=Homo sapiens HMG box containing protein 1 mRNA, complete cds. /FEA=mRNA /PROD=HMG box containing protein 1 /DB_XREF=gi:2460168 /UG=Hs.10882 HMG-box containing protein 1 /FL=gb:AF019214.1 AF019214 HMG-box transcription factor 1 HBP1 26959 NM_001244262 /// NM_012257 /// XM_005250266 /// XM_005250267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209103_s_at BC001049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001049.1 /DEF=Homo sapiens, Similar to ubiquitin fusion degradation 1 like, clone MGC:1385, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ubiquitin fusion degradation 1 like /DB_XREF=gi:12654446 /UG=Hs.181369 ubiquitin fusion degradation 1-like /FL=gb:BC001049.1 gb:BC005087.1 gb:AF141201.1 BC001049 ubiquitin fusion degradation 1 like (yeast) UFD1L 7353 NM_001035247 /// NM_005659 /// XM_005261276 /// XM_005261277 /// XM_006724319 0001501 // skeletal system development // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 209104_s_at BC000009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000009.1 /DEF=Homo sapiens, likely homolog of yeast Nhp2, component of the HACA snoRNP; hypothetical protein FLJ20479, clone MGC:1038, mRNA, complete cds. /FEA=mRNA /PROD=likely homolog of yeast Nhp2, component of theHACA snoRNP; hypothetical protein FLJ20479 /DB_XREF=gi:12652540 /UG=Hs.23990 nucleolar protein family A, member 2 (HACA small nucleolar RNPs) /FL=gb:BC000009.1 gb:NM_017838.1 BC000009 NHP2 ribonucleoprotein NHP2 55651 NM_001034833 /// NM_017838 0006364 // rRNA processing // inferred from electronic annotation /// 0031118 // rRNA pseudouridine synthesis // inferred from sequence or structural similarity /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 209105_at AI672428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI672428 /FEA=EST /DB_XREF=gi:4852159 /DB_XREF=est:wa03a11.x1 /CLONE=IMAGE:2296988 /UG=Hs.74002 nuclear receptor coactivator 1 /FL=gb:U19179.1 AI672428 nuclear receptor coactivator 1 NCOA1 8648 NM_003743 /// NM_147223 /// NM_147233 /// XM_005264625 /// XM_005264626 /// XM_005264627 /// XM_005264628 /// XM_006712126 0000435 // positive regulation of transcription from RNA polymerase II promoter by galactose // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 2001038 // regulation of cellular response to drug // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033142 // progesterone receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 209106_at BF576458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF576458 /FEA=EST /DB_XREF=gi:11650170 /DB_XREF=est:602133875F1 /CLONE=IMAGE:4288891 /UG=Hs.74002 nuclear receptor coactivator 1 /FL=gb:U19179.1 BF576458 nuclear receptor coactivator 1 NCOA1 8648 NM_003743 /// NM_147223 /// NM_147233 /// XM_005264625 /// XM_005264626 /// XM_005264627 /// XM_005264628 /// XM_006712126 0000435 // positive regulation of transcription from RNA polymerase II promoter by galactose // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 2001038 // regulation of cellular response to drug // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033142 // progesterone receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 209107_x_at U19179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19179.1 /DEF=Human (Hin-2) mRNA, complete cds. /FEA=mRNA /GEN=Hin-2 /DB_XREF=gi:726037 /UG=Hs.74002 nuclear receptor coactivator 1 /FL=gb:U19179.1 U19179 nuclear receptor coactivator 1 NCOA1 8648 NM_003743 /// NM_147223 /// NM_147233 /// XM_005264625 /// XM_005264626 /// XM_005264627 /// XM_005264628 /// XM_006712126 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000435 // positive regulation of transcription from RNA polymerase II promoter by galactose // inferred from direct assay /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 2001038 // regulation of cellular response to drug // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033142 // progesterone receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0071837 // HMG box domain binding // inferred from electronic annotation 209108_at AF053453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053453.1 /DEF=Homo sapiens tetraspan TM4SF (TSPAN-6) mRNA, complete cds. /FEA=mRNA /GEN=TSPAN-6 /PROD=tetraspan TM4SF /DB_XREF=gi:2995860 /UG=Hs.121068 transmembrane 4 superfamily member 6 /FL=gb:AF043906.1 gb:AF053453.1 gb:U84895.1 gb:NM_003270.1 gb:AF133426.1 AF053453 tetraspanin 6 TSPAN6 7105 NM_001278740 /// NM_001278741 /// NM_001278742 /// NM_001278743 /// NM_003270 0007165 // signal transduction // inferred from mutant phenotype /// 0039532 // negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 1901223 // negative regulation of NIK/NF-kappaB signaling // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 209109_s_at U84895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84895.1 /DEF=Human transmembrane 4 superfamily A15 homolog mRNA, complete cds. /FEA=mRNA /PROD=A15 homolog /DB_XREF=gi:4099210 /UG=Hs.121068 transmembrane 4 superfamily member 6 /FL=gb:AF043906.1 gb:AF053453.1 gb:U84895.1 gb:NM_003270.1 gb:AF133426.1 U84895 tetraspanin 6 TSPAN6 7105 NM_001278740 /// NM_001278741 /// NM_001278742 /// NM_001278743 /// NM_003270 0007165 // signal transduction // inferred from mutant phenotype /// 0039532 // negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 1901223 // negative regulation of NIK/NF-kappaB signaling // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 209110_s_at AL050259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL050259.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D0782 (from clone DKFZp564D0782); complete cds. /FEA=mRNA /GEN=DKFZp564D0782 /PROD=hypothetical protein /DB_XREF=gi:4886476 /UG=Hs.170160 RAB2, member RAS oncogene family-like /FL=gb:D85757.1 gb:NM_004761.1 gb:AL050259.1 AL050259 ral guanine nucleotide dissociation stimulator-like 2 RGL2 5863 NM_001243738 /// NM_004761 /// XM_005249256 /// XM_005249257 /// XM_005249258 /// XM_005272848 /// XM_005272849 /// XM_005272850 /// XM_005275004 /// XM_005275005 /// XM_005275006 /// XM_005275273 /// XM_005275274 /// XM_005275275 /// XM_005275434 /// XM_005275435 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0032318 // regulation of Ras GTPase activity // non-traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // non-traceable author statement 209111_at BC004155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004155.1 /DEF=Homo sapiens, ring finger protein 5, clone MGC:2407, mRNA, complete cds. /FEA=mRNA /PROD=ring finger protein 5 /DB_XREF=gi:13278761 /UG=Hs.216354 ring finger protein 5 /FL=gb:BC004155.1 gb:AB056869.1 gb:NM_006913.1 BC004155 ring finger protein 5, E3 ubiquitin protein ligase /// ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1 RNF5 /// RNF5P1 6048 /// 286140 NM_006913 /// NR_003129 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209112_at BC001971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001971.1 /DEF=Homo sapiens, Similar to cyclin-dependent kinase inhibitor 1B (p27, Kip1), clone MGC:5304, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cyclin-dependent kinase inhibitor 1B(p27, Kip1) /DB_XREF=gi:12805034 /UG=Hs.238990 cyclin-dependent kinase inhibitor 1B (p27, Kip1) /FL=gb:BC001971.1 gb:NM_004064.1 gb:U10906.1 gb:AF247551.1 gb:AY004255.1 BC001971 cyclin-dependent kinase inhibitor 1B (p27, Kip1) CDKN1B 1027 NM_004064 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048102 // autophagic cell death // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005072 // transforming growth factor beta receptor, cytoplasmic mediator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 209113_s_at AF288679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288679.1 /DEF=Homo sapiens smarce1-related protein mRNA, complete cds. /FEA=mRNA /PROD=smarce1-related protein /DB_XREF=gi:9858862 /UG=Hs.32317 high-mobility group 20B /FL=gb:AF331191.1 gb:BC003505.1 gb:BC004408.1 gb:AF072836.1 gb:NM_006339.1 gb:AF146223.1 gb:AF288679.1 AF288679 high mobility group 20B HMG20B 10362 NM_006339 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033234 // negative regulation of protein sumoylation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209114_at AF133425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF133425.1 /DEF=Homo sapiens tetraspanin TM4-C mRNA, complete cds. /FEA=mRNA /PROD=tetraspanin TM4-C /DB_XREF=gi:6434903 /UG=Hs.38972 tetraspan 1 /FL=gb:AF054838.1 gb:AF065388.1 gb:NM_005727.1 gb:AF133425.1 AF133425 tetraspanin 1 TSPAN1 10103 NM_005727 0008283 // cell proliferation // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from direct assay /// 0071934 // thiamine transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015403 // thiamine uptake transmembrane transporter activity // inferred from direct assay 209115_at AL117566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL117566.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566J164 (from clone DKFZp566J164); complete cds. /FEA=mRNA /GEN=DKFZp566J164 /PROD=hypothetical protein /DB_XREF=gi:5912116 /UG=Hs.154320 ubiquitin-activating enzyme E1C (homologous to yeast UBA3) /FL=gb:AF046024.1 gb:AB012190.1 gb:NM_003968.1 gb:AL117566.1 AL117566 ubiquitin-like modifier activating enzyme 3 UBA3 9039 NM_003968 /// NM_198195 /// NM_198197 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007113 // endomitotic cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045116 // protein neddylation // not recorded /// 0045116 // protein neddylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019781 // NEDD8 activating enzyme activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction 209116_x_at M25079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25079.1 /DEF=Human sickle cell beta-globin mRNA, complete cds. /FEA=mRNA /PROD=beta-globin /DB_XREF=gi:179408 /UG=Hs.155376 hemoglobin, beta /FL=gb:NM_000518.3 gb:M25079.1 gb:AF117710.1 gb:AF181989.1 M25079 hemoglobin, beta HBB 3043 NM_000518 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209117_at U79458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79458.1 /DEF=Human WW domain binding protein-2 mRNA, complete cds. /FEA=mRNA /PROD=WW domain binding protein-2 /DB_XREF=gi:4205085 /UG=Hs.231840 WW domain binding protein 2 /FL=gb:U79458.1 U79458 WW domain binding protein 2 WBP2 23558 NM_012478 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045815 // positive regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071391 // cellular response to estrogen stimulus // inferred from mutant phenotype /// 0071442 // positive regulation of histone H3-K14 acetylation // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from mutant phenotype /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from mutant phenotype 209118_s_at AF141347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF141347.1 /DEF=Homo sapiens hum-a-tub2 alpha-tubulin mRNA, complete cds. /FEA=mRNA /PROD=alpha-tubulin /DB_XREF=gi:4929133 /UG=Hs.272897 Tubulin, alpha, brain-specific /FL=gb:AF141347.1 gb:NM_006009.1 AF141347 tubulin, alpha 1a TUBA1A 7846 NM_001270399 /// NM_001270400 /// NM_006009 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 209119_x_at AV703465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV703465 /FEA=EST /DB_XREF=gi:10720792 /DB_XREF=est:AV703465 /CLONE=ADBCHG08 /UG=Hs.288869 nuclear receptor subfamily 2, group F, member 2 /FL=gb:M64497.1 AV703465 nuclear receptor subfamily 2, group F, member 2 NR2F2 7026 NM_001145155 /// NM_001145156 /// NM_001145157 /// NM_021005 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009956 // radial pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209120_at AL037401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037401 /FEA=EST /DB_XREF=gi:5406798 /DB_XREF=est:DKFZp564K1671_s1 /CLONE=DKFZp564K1671 /UG=Hs.288869 nuclear receptor subfamily 2, group F, member 2 /FL=gb:M64497.1 AL037401 nuclear receptor subfamily 2, group F, member 2 NR2F2 7026 NM_001145155 /// NM_001145156 /// NM_001145157 /// NM_021005 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009956 // radial pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209121_x_at M64497 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M64497.1 /DEF=Human apolipoprotein AI regulatory protein (ARP-1) mRNA, complete cds. /FEA=mRNA /GEN=ARP-1 /PROD=apolipoprotein AI regulatory protein-1 /DB_XREF=gi:179023 /UG=Hs.288869 nuclear receptor subfamily 2, group F, member 2 /FL=gb:M64497.1 M64497 nuclear receptor subfamily 2, group F, member 2 NR2F2 7026 NM_001145155 /// NM_001145156 /// NM_001145157 /// NM_021005 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009956 // radial pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209122_at BC005127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005127.1 /DEF=Homo sapiens, adipose differentiation-related protein, clone MGC:10598, mRNA, complete cds. /FEA=mRNA /PROD=adipose differentiation-related protein /DB_XREF=gi:13477306 /UG=Hs.3416 adipose differentiation-related protein /FL=gb:BC005127.1 gb:NM_001122.1 BC005127 perilipin 2 PLIN2 123 NM_001122 /// NR_038064 /// XM_006716719 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209123_at BC000576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000576.1 /DEF=Homo sapiens, quinoid dihydropteridine reductase, clone MGC:1657, mRNA, complete cds. /FEA=mRNA /PROD=quinoid dihydropteridine reductase /DB_XREF=gi:12653600 /UG=Hs.75438 quinoid dihydropteridine reductase /FL=gb:BC000576.1 gb:M16447.1 gb:NM_000320.1 BC000576 quinoid dihydropteridine reductase QDPR 5860 NM_000320 /// XR_241677 0001889 // liver development // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010044 // response to aluminum ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051066 // dihydrobiopterin metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004155 // 6,7-dihydropteridine reductase activity // not recorded /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from electronic annotation /// 0070404 // NADH binding // inferred from electronic annotation 209124_at U70451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U70451.1 /DEF=Human myleoid differentiation primary response protein MyD88 mRNA, complete cds. /FEA=mRNA /PROD=MyD88 /DB_XREF=gi:1763090 /UG=Hs.82116 myeloid differentiation primary response gene (88) /FL=gb:U70451.1 gb:U84408.1 gb:NM_002468.1 U70451 myeloid differentiation primary response 88 MYD88 4615 NM_001172566 /// NM_001172567 /// NM_001172568 /// NM_001172569 /// NM_002468 /// XM_005265172 /// XM_006713170 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002238 // response to molecule of fungal origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007254 // JNK cascade // inferred from electronic annotation /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032747 // positive regulation of interleukin-23 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050830 // defense response to Gram-positive bacterium // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005121 // Toll binding // inferred from electronic annotation /// 0005123 // death receptor binding // traceable author statement /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0070976 // TIR domain binding // inferred from physical interaction 209125_at J00269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J00269.1 /DEF=Human 56k cytoskeletal type II keratin mRNA. /FEA=mRNA /DB_XREF=gi:186699 /UG=Hs.111758 keratin 6A /FL=gb:NM_005554.1 gb:L42611.1 gb:L42612.1 J00269 keratin 6A KRT6A 3853 NM_005554 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209126_x_at L42612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L42612.1 /DEF=Homo sapiens keratin 6 isoform K6f (KRT6F) mRNA, complete cds. /FEA=mRNA /GEN=KRT6F /PROD=keratin type II /DB_XREF=gi:908804 /UG=Hs.111758 keratin 6A /FL=gb:NM_005554.1 gb:L42611.1 gb:L42612.1 L42612 keratin 6B KRT6B 3854 NM_005555 0007398 // ectoderm development // traceable author statement 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 209127_s_at AW173076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW173076 /FEA=EST /DB_XREF=gi:6439024 /DB_XREF=est:xj82h07.x1 /CLONE=IMAGE:2663773 /UG=Hs.116875 KIAA0156 gene product /FL=gb:AB020880.1 gb:NM_014706.1 gb:D63879.1 AW173076 squamous cell carcinoma antigen recognized by T cells 3 SART3 9733 NM_014706 /// XM_005269241 0006396 // RNA processing // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209128_s_at D63879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63879.1 /DEF=Human mRNA for KIAA0156 gene, complete cds. /FEA=mRNA /GEN=KIAA0156 /DB_XREF=gi:961449 /UG=Hs.116875 KIAA0156 gene product /FL=gb:AB020880.1 gb:NM_014706.1 gb:D63879.1 D63879 squamous cell carcinoma antigen recognized by T cells 3 SART3 9733 NM_014706 /// XM_005269241 0006396 // RNA processing // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209129_at AF000974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000974.1 /DEF=Human zyxin related protein ZRP-1 mRNA, complete cds. /FEA=mRNA /PROD=ZRP-1 /DB_XREF=gi:2232135 /UG=Hs.119498 thyroid hormone receptor interactor 6 /FL=gb:BC002680.1 gb:BC004249.1 gb:BC004999.1 gb:AF000974.1 AF000974 thyroid hormone receptor interactor 6 TRIP6 7205 NM_003302 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008588 // release of cytoplasmic sequestered NF-kappaB // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045323 // interleukin-1 receptor complex // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // non-traceable author statement 209130_at BC003686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003686.1 /DEF=Homo sapiens, synaptosomal-associated protein, 23kD, clone MGC:5155, mRNA, complete cds. /FEA=mRNA /PROD=synaptosomal-associated protein, 23kD /DB_XREF=gi:13277555 /UG=Hs.184376 synaptosomal-associated protein, 23kD /FL=gb:BC000148.2 gb:BC003686.1 gb:U55936.1 gb:Y09567.1 BC003686 synaptosomal-associated protein, 23kDa SNAP23 8773 NM_003825 /// NM_130798 /// XM_006720725 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209131_s_at U55936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U55936.1 /DEF=Human SNAP-23 mRNA, complete cds. /FEA=mRNA /PROD=SNAP-23 /DB_XREF=gi:1374812 /UG=Hs.184376 synaptosomal-associated protein, 23kD /FL=gb:BC000148.2 gb:BC003686.1 gb:U55936.1 gb:Y09567.1 U55936 synaptosomal-associated protein, 23kDa SNAP23 8773 NM_003825 /// NM_130798 /// XM_006720725 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209132_s_at BE313890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE313890 /FEA=EST /DB_XREF=gi:9134345 /DB_XREF=est:601148965F1 /CLONE=IMAGE:3501593 /UG=Hs.18490 hypothetical protein FLJ20452 /FL=gb:AL136872.1 BE313890 COMM domain containing 4 COMMD4 54939 NM_001284377 /// NM_001284378 /// NM_001284379 /// NM_017828 /// NR_104312 /// NR_104313 /// XM_005254509 /// XM_005254510 /// XM_005254511 /// XM_005254512 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209133_s_at AL136872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136872.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A155 (from clone DKFZp434A155); complete cds. /FEA=mRNA /GEN=DKFZp434A155 /PROD=hypothetical protein /DB_XREF=gi:12053248 /UG=Hs.18490 hypothetical protein FLJ20452 /FL=gb:AL136872.1 AL136872 COMM domain containing 4 COMMD4 54939 NM_001284377 /// NM_001284378 /// NM_001284379 /// NM_017828 /// NR_104312 /// NR_104313 /// XM_005254509 /// XM_005254510 /// XM_005254511 /// XM_005254512 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209134_s_at BC000524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000524.1 /DEF=Homo sapiens, Similar to ribosomal protein S6, clone MGC:8597, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein S6 /DB_XREF=gi:12653504 /UG=Hs.241507 ribosomal protein S6 /FL=gb:BC000524.1 gb:J03537.1 BC000524 ribosomal protein S6 RPS6 6194 NM_001010 0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209135_at AF289489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF289489.1 /DEF=Homo sapiens aspartyl beta-hydroxylase 2.8 kb transcript mRNA, complete cds; alternatively spliced. /FEA=mRNA /PROD=aspartyl beta-hydroxylase 2.8 kb transcript /DB_XREF=gi:11878115 /UG=Hs.283664 aspartate beta-hydroxylase /FL=gb:AF289489.1 AF289489 aspartate beta-hydroxylase ASPH 444 NM_001164750 /// NM_001164751 /// NM_001164752 /// NM_001164753 /// NM_001164754 /// NM_001164755 /// NM_001164756 /// NM_004318 /// NM_020164 /// NM_032466 /// NM_032467 /// NM_032468 /// XM_005251235 /// XM_005251236 /// XM_005251238 /// XM_005251239 /// XM_005251240 /// XM_005251241 /// XM_005251242 /// XM_005251243 /// XM_005251244 /// XM_005251246 /// XM_005251247 /// XM_005251248 /// XM_005251249 /// XM_005251250 /// XM_006716448 /// XM_006716449 0005513 // detection of calcium ion // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0018193 // peptidyl-amino acid modification // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0033198 // response to ATP // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1901879 // regulation of protein depolymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement /// 0034704 // calcium channel complex // traceable author statement 0004597 // peptide-aspartate beta-dioxygenase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 209136_s_at BG390445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG390445 /FEA=EST /DB_XREF=gi:13283893 /DB_XREF=est:602416083F1 /CLONE=IMAGE:4524309 /UG=Hs.78829 ubiquitin specific protease 10 /FL=gb:BC000263.1 BG390445 ubiquitin specific peptidase 10 USP10 9100 NM_001272075 /// NM_005153 /// NR_073577 /// NR_073578 /// XM_006721330 /// XM_006721331 /// XM_006721332 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209137_s_at BC000263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000263.1 /DEF=Homo sapiens, Similar to ubiquintin c-terminal hydrolase related polypeptide, clone MGC:2621, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ubiquintin c-terminal hydrolaserelated polypeptide /DB_XREF=gi:12653004 /UG=Hs.78829 ubiquitin specific protease 10 /FL=gb:BC000263.1 BC000263 ubiquitin specific peptidase 10 USP10 9100 NM_001272075 /// NM_005153 /// NR_073577 /// NR_073578 /// XM_006721330 /// XM_006721331 /// XM_006721332 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209138_x_at M87790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M87790.1 /DEF=Human (hybridoma H210) anti-hepatitis A immunoglobulin lambda chain variable region, constant region, complementarity-determining regions mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin lambda-chain /DB_XREF=gi:185363 /UG=Hs.181125 immunoglobulin lambda locus /FL=gb:M87790.1 M87790 immunoglobulin lambda constant 1 (Mcg marker) IGLC1 3537 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 209139_s_at AF083033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083033.1 /DEF=Homo sapiens PKR-associating protein RAX mRNA, complete cds. /FEA=mRNA /PROD=PKR-associating protein RAX /DB_XREF=gi:4927415 /UG=Hs.18571 protein kinase, interferon-inducible double stranded RNA dependent activator /FL=gb:AF072860.1 gb:NM_003690.1 gb:AF083033.1 AF083033 protein kinase, interferon-inducible double stranded RNA dependent activator PRKRA 8575 NM_001139517 /// NM_001139518 /// NM_003690 /// XM_005246921 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209140_x_at L42024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L42024.1 /DEF=Homo sapiens MHC HLA-B39 mRNA, complete cds. /FEA=mRNA /GEN=HLA-B39 /PROD=major histocompatibility complex /DB_XREF=gi:804748 /UG=Hs.77961 major histocompatibility complex, class I, B /FL=gb:L37880.1 gb:U29057.1 gb:U29480.1 gb:U63653.1 gb:D85761.1 gb:D85762.1 gb:M77774.1 gb:M77778.1 gb:M77777.1 gb:M16102.1 gb:M84380.1 gb:M32317.1 gb:M24033.1 gb:L17005.1 gb:U88407.1 gb:U29083.1 gb:L24373.1 gb:U03698.1 gb:U04787.1 gb:U04244.1 gb:U04245.1 gb:NM_005514.1 gb:L33922.1 gb:AF189017.1 gb:U21052.1 gb:U21053.1 gb:L36318.1 gb:U09912.1 gb:L42024.1 L42024 major histocompatibility complex, class I, B HLA-B 3106 NM_005514 /// XM_005249043 /// XM_005275100 /// XM_005275238 /// XM_005275376 /// XM_005275377 /// XM_005275535 /// XM_006725904 /// XM_006725905 /// XR_246962 /// XR_427830 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0002667 // regulation of T cell anergy // inferred from mutant phenotype /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032655 // regulation of interleukin-12 production // inferred from mutant phenotype /// 0032675 // regulation of interleukin-6 production // inferred from mutant phenotype /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001198 // regulation of dendritic cell differentiation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 209141_at AW299555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299555 /FEA=EST /DB_XREF=gi:6709232 /DB_XREF=est:xs51d10.x1 /CLONE=IMAGE:2773171 /UG=Hs.78563 ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7) /FL=gb:BC002775.1 gb:NM_003342.1 gb:D78514.1 AW299555 ubiquitin-conjugating enzyme E2G 1 UBE2G1 7326 NM_003342 /// NM_182682 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 209142_s_at BC002775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002775.1 /DEF=Homo sapiens, Similar to CG9602 gene product, clone MGC:3733, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG9602 gene product /DB_XREF=gi:12803862 /UG=Hs.78563 ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7) /FL=gb:BC002775.1 gb:NM_003342.1 gb:D78514.1 BC002775 ubiquitin-conjugating enzyme E2G 1 UBE2G1 7326 NM_003342 /// NM_182682 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 209143_s_at AF005422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005422.1 /DEF=Homo sapiens reticulocyte pICln mRNA, complete cds. /FEA=mRNA /PROD=reticulocyte pICln /DB_XREF=gi:2209234 /UG=Hs.84974 chloride channel, nucleotide-sensitive, 1A /FL=gb:U53454.1 gb:AF005422.1 gb:AF026003.1 gb:NM_001293.1 gb:U17899.1 AF005422 chloride channel, nucleotide-sensitive, 1A CLNS1A 1207 NM_001293 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006810 // transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209144_s_at AI810484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI810484 /FEA=EST /DB_XREF=gi:5397050 /DB_XREF=est:wb89b11.x1 /CLONE=IMAGE:2312829 /UG=Hs.153934 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 /FL=gb:AF068266.1 gb:AF069747.1 AI810484 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 CBFA2T2 9139 NM_001032999 /// NM_001039709 /// NM_005093 /// NM_175864 /// XM_006723886 /// XM_006723887 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209145_s_at AF068266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068266.1 /DEF=Homo sapiens EHT protein mRNA, complete cds. /FEA=mRNA /PROD=EHT protein /DB_XREF=gi:3201989 /UG=Hs.153934 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 /FL=gb:AF068266.1 gb:AF069747.1 AF068266 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 CBFA2T2 9139 NM_001032999 /// NM_001039709 /// NM_005093 /// NM_175864 /// XM_006723886 /// XM_006723887 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209146_at AV704962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV704962 /FEA=EST /DB_XREF=gi:10722273 /DB_XREF=est:AV704962 /CLONE=ADBALE09 /UG=Hs.239926 sterol-C4-methyl oxidase-like /FL=gb:U60205.1 gb:U93162.1 gb:NM_006745.2 AV704962 methylsterol monooxygenase 1 MSMO1 6307 NM_001017369 /// NM_006745 /// XM_005263176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000254 // C-4 methylsterol oxidase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 209147_s_at AB000888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000888.1 /DEF=Homo sapiens mRNA for phosphatidic acid phosphatase 2a, complete cds. /FEA=mRNA /PROD=phosphatidic acid phosphatase 2a /DB_XREF=gi:2467297 /UG=Hs.41569 phosphatidic acid phosphatase type 2A /FL=gb:AB000888.1 gb:AF017116.1 gb:AF014402.1 gb:NM_003711.1 AB000888 phosphatidic acid phosphatase type 2A PPAP2A 8611 NM_003711 /// NM_176895 /// NR_103485 /// XM_006714724 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0008354 // germ cell migration // traceable author statement /// 0019216 // regulation of lipid metabolic process // non-traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046839 // phospholipid dephosphorylation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from direct assay /// 0008195 // phosphatidate phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 209148_at BC001167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001167.1 /DEF=Homo sapiens, retinoid X receptor, beta, clone MGC:1831, mRNA, complete cds. /FEA=mRNA /PROD=retinoid X receptor, beta /DB_XREF=gi:12654658 /UG=Hs.79372 retinoid X receptor, beta /FL=gb:NM_021976.1 gb:BC001167.1 gb:M84820.1 BC001167 retinoid X receptor, beta RXRB 6257 NM_001270401 /// NM_001291989 /// NM_021976 /// XM_005249278 /// XM_005249279 /// XM_005272854 /// XM_005272855 /// XM_005275007 /// XM_005275008 /// XM_005275149 /// XM_005275150 /// XM_005275276 /// XM_005275277 /// XM_005275438 /// XM_005275439 /// XM_006715162 /// XM_006725494 /// XM_006725708 /// XM_006725825 /// XM_006725917 /// XM_006726010 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209149_s_at BE899402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE899402 /FEA=EST /DB_XREF=gi:10367069 /DB_XREF=est:601681419F1 /CLONE=IMAGE:3951724 /UG=Hs.91586 transmembrane 9 superfamily member 1 /FL=gb:U94831.1 gb:NM_006405.1 BE899402 transmembrane 9 superfamily member 1 TM9SF1 10548 NM_001014842 /// NM_001289006 /// NM_006405 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 209150_s_at U94831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94831.1 /DEF=Homo sapiens multispanning membrane protein mRNA, complete cds. /FEA=mRNA /PROD=multispanning membrane protein /DB_XREF=gi:2276459 /UG=Hs.91586 transmembrane 9 superfamily member 1 /FL=gb:U94831.1 gb:NM_006405.1 U94831 importin 4 /// transmembrane 9 superfamily member 1 IPO4 /// TM9SF1 10548 /// 79711 NM_001014842 /// NM_001289006 /// NM_006405 /// NM_024658 /// NR_051979 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0008536 // Ran GTPase binding // inferred from electronic annotation 209151_x_at AA768906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA768906 /FEA=EST /DB_XREF=gi:2820144 /DB_XREF=est:nz82g10.s1 /CLONE=IMAGE:1302018 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) /FL=gb:M31523.1 AA768906 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 209152_s_at AI655986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655986 /FEA=EST /DB_XREF=gi:4739965 /DB_XREF=est:tt42b10.x1 /CLONE=IMAGE:2243419 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) /FL=gb:M31523.1 AI655986 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 209153_s_at M31523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31523.1 /DEF=Human transcription factor (E2A) mRNA, complete cds. /FEA=mRNA /GEN=TCF3 /DB_XREF=gi:339477 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) /FL=gb:M31523.1 M31523 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 209154_at AF234997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF234997.1 /DEF=Homo sapiens glutaminase-interacting protein 3 mRNA, complete cds. /FEA=mRNA /PROD=glutaminase-interacting protein 3 /DB_XREF=gi:12005281 /UG=Hs.12956 Tax interaction protein 1 /FL=gb:AF028823.2 gb:NM_014604.1 gb:AF234997.1 AF234997 P2RX5-TAX1BP3 readthrough (NMD candidate) /// Tax1 (human T-cell leukemia virus type I) binding protein 3 P2RX5-TAX1BP3 /// TAX1BP3 30851 /// 100533970 NM_001204698 /// NM_014604 /// NR_037928 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032864 // activation of Cdc42 GTPase activity // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // inferred from electronic annotation /// 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction 209155_s_at BC001595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001595.1 /DEF=Homo sapiens, 5-nucleotidase (purine), cytosolic type B, clone MGC:1109, mRNA, complete cds. /FEA=mRNA /PROD=5-nucleotidase (purine), cytosolic type B /DB_XREF=gi:12804388 /UG=Hs.138593 5-nucleotidase (purine), cytosolic type B /FL=gb:BC001595.1 BC001595 5'-nucleotidase, cytosolic II NT5C2 22978 NM_001134373 /// NM_012229 /// XM_005269632 /// XM_005269633 /// XM_005269634 /// XM_005269635 /// XM_005269636 /// XM_005269637 /// XM_005269638 /// XM_005269639 /// XM_005269640 /// XM_005269641 /// XM_005269642 /// XM_005269643 /// XM_005269644 /// XM_005269645 /// XM_005269646 /// XM_006717721 /// XM_006717722 /// XM_006717723 /// XM_006717724 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0016311 // dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017144 // drug metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008253 // 5'-nucleotidase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050146 // nucleoside phosphotransferase activity // traceable author statement 209156_s_at AY029208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY029208.1 /DEF=Homo sapiens type VI collagen alpha 2 chain precursor (COL6A2) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=COL6A2 /PROD=type VI collagen alpha 2 chain precursor /DB_XREF=gi:13603393 /UG=Hs.159263 collagen, type VI, alpha 2 /FL=gb:AY029208.1 AY029208 collagen, type VI, alpha 2 COL6A2 1292 NM_001849 /// NM_058174 /// NM_058175 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement 209157_at AF011793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF011793.1 /DEF=Homo sapiens DNJ3CPR3 mRNA, complete cds. /FEA=mRNA /GEN=DNJ3CPR3 /PROD=Dnj3Cpr3 /DB_XREF=gi:2352903 /UG=Hs.21189 DnaJ (Hsp40) homolog, subfamily A, member 2 /FL=gb:AF011793.1 gb:NM_005880.2 AF011793 DnaJ (Hsp40) homolog, subfamily A, member 2 DNAJA2 10294 NM_005880 0006457 // protein folding // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 209158_s_at BC004361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004361.1 /DEF=Homo sapiens, pleckstrin homology, Sec7 and coiledcoil domains 2 (cytohesin-2), clone MGC:642, mRNA, complete cds. /FEA=mRNA /PROD=pleckstrin homology, Sec7 and coiledcoildomains 2 (cytohesin-2) /DB_XREF=gi:13279334 /UG=Hs.303091 pleckstrin homology, Sec7 and coiledcoil domains 2 (cytohesin-2) /FL=gb:NM_017457.2 gb:NM_004228.3 gb:BC004361.1 gb:U70728.1 BC004361 cytohesin 2 CYTH2 9266 NM_004228 /// NM_017457 /// XM_006723472 /// XM_006723473 0006897 // endocytosis // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030155 // regulation of cell adhesion // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from sequence or structural similarity 209159_s_at AV724216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV724216 /FEA=EST /DB_XREF=gi:10828381 /DB_XREF=est:AV724216 /CLONE=HTBARB01 /UG=Hs.322430 NDRG family, member 4 /FL=gb:AB044944.1 gb:AL136584.1 AV724216 NDRG family member 4 NDRG4 65009 NM_001130487 /// NM_001242833 /// NM_001242834 /// NM_001242835 /// NM_001242836 /// NM_020465 /// NM_022910 /// NR_040072 /// XM_006721252 /// XM_006721253 /// XM_006721254 /// XM_006721255 /// XM_006721256 /// XM_006721257 /// XM_006721258 /// XM_006721259 /// XM_006721260 /// XM_006721261 /// XM_006721262 0006950 // response to stress // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 209160_at AB018580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB018580.1 /DEF=Homo sapiens mRNA for hluPGFS, complete cds. /FEA=mRNA /GEN=c-hluPGFS /PROD=hluPGFS /DB_XREF=gi:6624210 /UG=Hs.78183 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) /FL=gb:AF149416.2 gb:NM_003739.2 gb:D17793.1 gb:AB018580.1 AB018580 aldo-keto reductase family 1, member C3 AKR1C3 8644 NM_001253908 /// NM_001253909 /// NM_003739 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0001523 // retinoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // inferred from expression pattern /// 0006693 // prostaglandin metabolic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007584 // response to nutrient // inferred from expression pattern /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from expression pattern /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from expression pattern /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016488 // farnesol catabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0044259 // multicellular organismal macromolecule metabolic process // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0048385 // regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0061370 // testosterone biosynthetic process // inferred from mutant phenotype /// 0070293 // renal absorption // non-traceable author statement /// 0071276 // cellular response to cadmium ion // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071379 // cellular response to prostaglandin stimulus // inferred from direct assay /// 0071384 // cellular response to corticosteroid stimulus // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay /// 1900053 // negative regulation of retinoic acid biosynthetic process // inferred from direct assay /// 2000224 // regulation of testosterone biosynthetic process // inferred from mutant phenotype /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001758 // retinal dehydrogenase activity // inferred from direct assay /// 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004745 // retinol dehydrogenase activity // inferred from direct assay /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0035410 // dihydrotestosterone 17-beta-dehydrogenase activity // inferred from direct assay /// 0036131 // prostaglandin D2 11-ketoreductase activity // inferred from electronic annotation /// 0045550 // geranylgeranyl reductase activity // inferred from direct assay /// 0045703 // ketoreductase activity // inferred from direct assay /// 0047017 // prostaglandin-F synthase activity // inferred from electronic annotation /// 0047020 // 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity // inferred from direct assay /// 0047023 // androsterone dehydrogenase activity // inferred from direct assay /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0047045 // testosterone 17-beta-dehydrogenase (NADP+) activity // inferred from electronic annotation /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from electronic annotation /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation /// 0047787 // delta4-3-oxosteroid 5beta-reductase activity // inferred from direct assay 209161_at AI184802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI184802 /FEA=EST /DB_XREF=gi:3735440 /DB_XREF=est:qd24g04.x1 /CLONE=IMAGE:1724694 /UG=Hs.8551 PRP4STKWD splicing factor /FL=gb:AF016369.1 gb:U82756.1 gb:NM_004697.1 AI184802 pre-mRNA processing factor 4 PRPF4 9128 NM_001244926 /// NM_004697 /// XM_005252300 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred by curator /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071001 // U4/U6 snRNP // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209162_s_at U82756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82756.1 /DEF=Homo sapiens WD splicing factor Hprp4p (HPRP4) mRNA, complete cds. /FEA=mRNA /GEN=HPRP4 /PROD=WD splicing factor Hprp4p /DB_XREF=gi:2853276 /UG=Hs.8551 PRP4STKWD splicing factor /FL=gb:AF016369.1 gb:U82756.1 gb:NM_004697.1 U82756 pre-mRNA processing factor 4 PRPF4 9128 NM_001244926 /// NM_004697 /// XM_005252300 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred by curator /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071001 // U4/U6 snRNP // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209163_at AL514271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL514271 /FEA=EST /DB_XREF=gi:12777765 /DB_XREF=est:AL514271 /CLONE=CL0BB007ZE10 (3 prime) /UG=Hs.153028 cytochrome b-561 /FL=gb:BC002976.1 AL514271 cytochrome b561 CYB561 1534 NM_001017916 /// NM_001017917 /// NM_001017918 /// NM_001915 /// XM_005257090 /// XM_005257091 /// XM_005257092 /// XM_006721727 0022900 // electron transport chain // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000293 // ferric-chelate reductase activity // inferred from sequence or structural similarity /// 0022865 // transmembrane electron transfer carrier // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209164_s_at BC002976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002976.1 /DEF=Homo sapiens, Similar to cytochrome b-561, clone MGC:2190, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cytochrome b-561 /DB_XREF=gi:12804234 /UG=Hs.153028 cytochrome b-561 /FL=gb:BC002976.1 BC002976 cytochrome b561 CYB561 1534 NM_001017916 /// NM_001017917 /// NM_001017918 /// NM_001915 /// XM_005257090 /// XM_005257091 /// XM_005257092 /// XM_006721727 0022900 // electron transport chain // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000293 // ferric-chelate reductase activity // inferred from sequence or structural similarity /// 0022865 // transmembrane electron transfer carrier // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209165_at AF083208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083208.1 /DEF=Homo sapiens Che-1 mRNA, complete cds. /FEA=mRNA /PROD=Che-1 /DB_XREF=gi:5813798 /UG=Hs.16178 apoptosis antagonizing transcription factor /FL=gb:BC000591.1 gb:AF083208.1 gb:NM_012138.1 AF083208 apoptosis antagonizing transcription factor AATF 26574 NM_012138 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0032929 // negative regulation of superoxide anion generation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042985 // negative regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048156 // tau protein binding // inferred from electronic annotation 209166_s_at U68567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U68567.1 /DEF=Human lysosomal acid alpha-mannosidase mRNA, complete cds. /FEA=mRNA /PROD=lysosomal acid alpha-mannosidase /DB_XREF=gi:1658373 /UG=Hs.279854 mannosidase, alpha, class 2B, member 1 /FL=gb:NM_000528.1 gb:BC000736.1 gb:U05572.1 gb:U68567.1 gb:U60266.1 U68567 mannosidase, alpha, class 2B, member 1 MAN2B1 4125 NM_000528 /// NM_001173498 /// XM_005259913 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006517 // protein deglycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209167_at AI419030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI419030 /FEA=EST /DB_XREF=gi:4264961 /DB_XREF=est:tf53b01.x1 /CLONE=IMAGE:2102953 /UG=Hs.5422 glycoprotein M6B /FL=gb:AF016004.1 AI419030 glycoprotein M6B GPM6B 2824 NM_001001994 /// NM_001001995 /// NM_001001996 /// NM_005278 /// XM_005274489 /// XM_005274490 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0051612 // negative regulation of serotonin uptake // inferred from sequence or structural similarity /// 0051893 // regulation of focal adhesion assembly // inferred from mutant phenotype /// 0085029 // extracellular matrix assembly // inferred from mutant phenotype /// 2000009 // negative regulation of protein localization to cell surface // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 209168_at AW148844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW148844 /FEA=EST /DB_XREF=gi:6196740 /DB_XREF=est:xf05c06.x1 /CLONE=IMAGE:2617162 /UG=Hs.5422 glycoprotein M6B /FL=gb:AF016004.1 AW148844 glycoprotein M6B GPM6B 2824 NM_001001994 /// NM_001001995 /// NM_001001996 /// NM_005278 /// XM_005274489 /// XM_005274490 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0051612 // negative regulation of serotonin uptake // inferred from sequence or structural similarity /// 0051893 // regulation of focal adhesion assembly // inferred from mutant phenotype /// 0085029 // extracellular matrix assembly // inferred from mutant phenotype /// 2000009 // negative regulation of protein localization to cell surface // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 209169_at N63576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N63576 /FEA=EST /DB_XREF=gi:1211405 /DB_XREF=est:yy63f07.s1 /CLONE=IMAGE:278245 /UG=Hs.5422 glycoprotein M6B /FL=gb:AF016004.1 N63576 glycoprotein M6B GPM6B 2824 NM_001001994 /// NM_001001995 /// NM_001001996 /// NM_005278 /// XM_005274489 /// XM_005274490 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0051612 // negative regulation of serotonin uptake // inferred from sequence or structural similarity /// 0051893 // regulation of focal adhesion assembly // inferred from mutant phenotype /// 0085029 // extracellular matrix assembly // inferred from mutant phenotype /// 2000009 // negative regulation of protein localization to cell surface // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 209170_s_at AF016004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF016004.1 /DEF=Homo sapiens m6b1 mRNA, complete cds. /FEA=mRNA /GEN=m6b1 /DB_XREF=gi:3387766 /UG=Hs.5422 glycoprotein M6B /FL=gb:AF016004.1 AF016004 glycoprotein M6B GPM6B 2824 NM_001001994 /// NM_001001995 /// NM_001001996 /// NM_005278 /// XM_005274489 /// XM_005274490 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0051612 // negative regulation of serotonin uptake // inferred from sequence or structural similarity /// 0051893 // regulation of focal adhesion assembly // inferred from mutant phenotype /// 0085029 // extracellular matrix assembly // inferred from mutant phenotype /// 2000009 // negative regulation of protein localization to cell surface // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 209171_at AF219116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF219116.1 /DEF=Homo sapiens inosine triphosphate pyrophosphatase (ITPA) mRNA, complete cds. /FEA=mRNA /GEN=ITPA /PROD=inosine triphosphate pyrophosphatase /DB_XREF=gi:13398327 /UG=Hs.6817 putative oncogene protein hlc14-06-p /FL=gb:AF063607.1 gb:AF026816.2 gb:NM_025200.1 gb:AF219116.1 AF219116 inosine triphosphatase (nucleoside triphosphate pyrophosphatase) ITPA 3704 NM_001267623 /// NM_033453 /// NM_181493 /// NR_052000 /// NR_052001 /// NR_052002 /// XM_006723564 /// XM_006723565 0006193 // ITP catabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009143 // nucleoside triphosphate catabolic process // inferred from electronic annotation /// 0009204 // deoxyribonucleoside triphosphate catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035870 // dITP diphosphatase activity // not recorded /// 0036220 // ITP diphosphatase activity // not recorded /// 0036222 // XTP diphosphatase activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047429 // nucleoside-triphosphate diphosphatase activity // inferred from electronic annotation 209172_s_at U30872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U30872.1 /DEF=Human mitosin mRNA, complete cds. /FEA=mRNA /PROD=mitosin /DB_XREF=gi:1000093 /UG=Hs.77204 centromere protein F (350400kD, mitosin) /FL=gb:U30872.1 U30872 centromere protein F, 350/400kDa CENPF 1063 NM_016343 0000085 // mitotic G2 phase // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from direct assay /// 0000087 // mitotic M phase // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007059 // chromosome segregation // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0015031 // protein transport // inferred from direct assay /// 0015031 // protein transport // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051310 // metaphase plate congression // inferred from direct assay /// 0051382 // kinetochore assembly // non-traceable author statement /// 0051726 // regulation of cell cycle // traceable author statement 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000785 // chromatin // non-traceable author statement /// 0000922 // spindle pole // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0045502 // dynein binding // inferred from direct assay 209173_at AF088867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF088867.1 /DEF=Homo sapiens putative secreted protein XAG mRNA, complete cds. /FEA=mRNA /PROD=putative secreted protein XAG /DB_XREF=gi:6652811 /UG=Hs.91011 anterior gradient 2 (Xenepus laevis) homolog /FL=gb:AF007791.1 gb:AF038451.1 gb:NM_006408.1 gb:AF088867.1 AF088867 anterior gradient 2 AGR2 10551 NM_006408 /// XM_005249581 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0070254 // mucus secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity 0002162 // dystroglycan binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209174_s_at BC000978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000978.2 /DEF=Homo sapiens, hypothetical protein FLJ20259, clone MGC:5396, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20259 /DB_XREF=gi:12803027 /UG=Hs.9956 hypothetical protein FLJ20259 /FL=gb:BC000978.2 gb:NM_017730.1 BC000978 glutamine-rich 1 QRICH1 54870 NM_017730 /// NM_198880 /// XM_005265248 /// XM_006713212 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 209175_at AK001135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001135.1 /DEF=Homo sapiens cDNA FLJ10273 fis, clone HEMBB1001137, highly similar to Homo sapiens mRNA for putative phospholipase. /FEA=mRNA /DB_XREF=gi:7022202 /UG=Hs.300208 Sec23-interacting protein p125 /FL=gb:BC002540.1 gb:AB019435.1 gb:NM_007190.1 AK001135 SEC23 interacting protein SEC23IP 11196 NM_007190 /// NR_037771 /// XM_005269469 /// XM_005269470 /// XR_246061 0006886 // intracellular protein transport // traceable author statement /// 0007030 // Golgi organization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209176_at AI332962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI332962 /FEA=EST /DB_XREF=gi:4069521 /DB_XREF=est:qq33c01.x1 /CLONE=IMAGE:1934304 /UG=Hs.300208 Sec23-interacting protein p125 /FL=gb:BC002540.1 gb:AB019435.1 gb:NM_007190.1 AI332962 SEC23 interacting protein SEC23IP 11196 NM_007190 /// NR_037771 /// XM_005269469 /// XM_005269470 /// XR_246061 0006886 // intracellular protein transport // traceable author statement /// 0007030 // Golgi organization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209177_at BC002873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002873.1 /DEF=Homo sapiens, Similar to nuclear protein E3-3 orf1, clone MGC:10527, mRNA, complete cds. /FEA=mRNA /PROD=Similar to nuclear protein E3-3 orf1 /DB_XREF=gi:12804040 /UG=Hs.31387 DKFZP564J0123 protein /FL=gb:BC002873.1 BC002873 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 NDUFAF3 25915 NM_199069 /// NM_199070 /// NM_199073 /// NM_199074 /// NM_199417 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209178_at AF038391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF038391.1 /DEF=Homo sapiens pre-mRNA splicing factor (PRP16) mRNA, complete cds. /FEA=mRNA /GEN=PRP16 /PROD=pre-mRNA splicing factor /DB_XREF=gi:3123905 /UG=Hs.78054 pre-mRNA splicing factor similar to S. cerevisiae Prp16 /FL=gb:BC004235.1 gb:D86977.1 gb:AF038391.1 gb:NM_014003.1 AF038391 DEAH (Asp-Glu-Ala-His) box polypeptide 38 DHX38 9785 NM_014003 /// XM_005256269 /// XR_429741 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209179_s_at BC003164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003164.1 /DEF=Homo sapiens, clone MGC:4221, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4221) /DB_XREF=gi:13111982 /UG=Hs.78768 malignant cell expression-enhanced genetumor progression-enhanced gene /FL=gb:BC002512.1 gb:BC003164.1 BC003164 membrane bound O-acyltransferase domain containing 7 MBOAT7 79143 NM_001146056 /// NM_001146082 /// NM_001146083 /// NM_024298 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 209180_at U49245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49245.1 /DEF=Human geranylgeranyl transferase type II beta-subunit mRNA, complete cds. /FEA=mRNA /PROD=geranylgeranyl transferase type II beta-subunit /DB_XREF=gi:1216503 /UG=Hs.78948 Rab geranylgeranyltransferase, beta subunit /FL=gb:U49245.1 gb:NM_004582.1 U49245 Rab geranylgeranyltransferase, beta subunit RABGGTB 5876 NM_004582 /// NR_073562 0006464 // cellular protein modification process // non-traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209181_s_at U49245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49245.1 /DEF=Human geranylgeranyl transferase type II beta-subunit mRNA, complete cds. /FEA=mRNA /PROD=geranylgeranyl transferase type II beta-subunit /DB_XREF=gi:1216503 /UG=Hs.78948 Rab geranylgeranyltransferase, beta subunit /FL=gb:U49245.1 gb:NM_004582.1 U49245 Rab geranylgeranyltransferase, beta subunit /// small nucleolar RNA, C/D box 45A /// small nucleolar RNA, C/D box 45B /// small nucleolar RNA, C/D box 45C RABGGTB /// SNORD45A /// SNORD45B /// SNORD45C 5876 /// 26804 /// 26805 /// 692085 NM_004582 /// NR_002748 /// NR_002749 /// NR_003042 /// NR_073562 0006464 // cellular protein modification process // non-traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209182_s_at AI302100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI302100 /FEA=EST /DB_XREF=gi:3961446 /DB_XREF=est:qn57g11.x1 /CLONE=IMAGE:1902404 /UG=Hs.93675 decidual protein induced by progesterone /FL=gb:AB022718.1 gb:NM_007021.1 gb:AL136653.1 AI302100 chromosome 10 open reading frame 10 C10orf10 11067 NM_007021 0005739 // mitochondrion // inferred from direct assay 209183_s_at AL136653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136653.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P1263 (from clone DKFZp564P1263); complete cds. /FEA=mRNA /GEN=DKFZp564P1263 /PROD=hypothetical protein /DB_XREF=gi:6807650 /UG=Hs.93675 decidual protein induced by progesterone /FL=gb:AB022718.1 gb:NM_007021.1 gb:AL136653.1 AL136653 chromosome 10 open reading frame 10 C10orf10 11067 NM_007021 0005739 // mitochondrion // inferred from direct assay 209184_s_at BF700086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF700086 /FEA=EST /DB_XREF=gi:11985494 /DB_XREF=est:602127569F1 /CLONE=IMAGE:4284401 /UG=Hs.143648 insulin receptor substrate 2 /FL=gb:NM_003749.1 gb:AF073310.1 BF700086 insulin receptor substrate 2 IRS2 8660 NM_003749 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0019216 // regulation of lipid metabolic process // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0055088 // lipid homeostasis // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 209185_s_at AF073310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF073310.1 /DEF=Homo sapiens insulin receptor substrate-2 (IRS2) mRNA, complete cds. /FEA=mRNA /GEN=IRS2 /PROD=insulin receptor substrate-2 /DB_XREF=gi:4511968 /UG=Hs.143648 insulin receptor substrate 2 /FL=gb:NM_003749.1 gb:AF073310.1 AF073310 insulin receptor substrate 2 IRS2 8660 NM_003749 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0019216 // regulation of lipid metabolic process // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0055088 // lipid homeostasis // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 209186_at M23114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M23114.1 /DEF=Homo sapiens calcium-ATPase (HK1) mRNA, complete cds. /FEA=mRNA /GEN=HK1 /DB_XREF=gi:184100 /UG=Hs.1526 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 /FL=gb:M23114.1 M23114 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ATP2A2 488 NM_001135765 /// NM_001681 /// NM_170665 /// XM_005253888 /// XR_243009 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006984 // ER-nucleus signaling pathway // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010460 // positive regulation of heart rate // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0086036 // regulation of cardiac muscle cell membrane potential // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0086039 // calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential // traceable author statement 209187_at AW516932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW516932 /FEA=EST /DB_XREF=gi:7154941 /DB_XREF=est:xq04a05.x1 /CLONE=IMAGE:2748848 /UG=Hs.16697 down-regulator of transcription 1, TBP-binding (negative cofactor 2) /FL=gb:BC002809.1 AW516932 down-regulator of transcription 1, TBP-binding (negative cofactor 2) DR1 1810 NM_001938 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209188_x_at BC002809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002809.1 /DEF=Homo sapiens, down-regulator of transcription 1, TBP-binding (negative cofactor 2), clone MGC:4292, mRNA, complete cds. /FEA=mRNA /PROD=down-regulator of transcription 1, TBP-binding(negative cofactor 2) /DB_XREF=gi:12803924 /UG=Hs.16697 down-regulator of transcription 1, TBP-binding (negative cofactor 2) /FL=gb:BC002809.1 BC002809 down-regulator of transcription 1, TBP-binding (negative cofactor 2) DR1 1810 NM_001938 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209189_at BC004490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004490.1 /DEF=Homo sapiens, v-fos FBJ murine osteosarcoma viral oncogene homolog, clone MGC:11074, mRNA, complete cds. /FEA=mRNA /PROD=v-fos FBJ murine osteosarcoma viral oncogenehomolog /DB_XREF=gi:13325363 /UG=Hs.25647 v-fos FBJ murine osteosarcoma viral oncogene homolog /FL=gb:BC004490.1 gb:NM_005252.2 BC004490 FBJ murine osteosarcoma viral oncogene homolog FOS 2353 NM_005252 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction 209190_s_at AF051782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051782.1 /DEF=Homo sapiens diaphanous 1 (HDIA1) mRNA, complete cds. /FEA=mRNA /GEN=HDIA1 /PROD=diaphanous 1 /DB_XREF=gi:2947237 /UG=Hs.26584 diaphanous (Drosophila, homolog) 1 /FL=gb:AF051782.1 gb:NM_005219.1 AF051782 diaphanous-related formin 1 DIAPH1 1729 NM_001079812 /// NM_005219 /// XM_005268384 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071420 // cellular response to histamine // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209191_at BC002654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002654.1 /DEF=Homo sapiens, Similar to tubulin, beta, 4, clone MGC:4083, mRNA, complete cds. /FEA=mRNA /PROD=Similar to tubulin, beta, 4 /DB_XREF=gi:12803638 /UG=Hs.274398 Homo sapiens, Similar to tubulin, beta, 4, clone MGC:4083, mRNA, complete cds /FL=gb:BC002654.1 BC002654 tubulin, beta 6 class V TUBB6 84617 NM_032525 /// XM_005258159 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 209192_x_at BC000166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000166.2 /DEF=Homo sapiens, HIV-1 Tat interactive protein, 60 kDa, clone MGC:5108, mRNA, complete cds. /FEA=mRNA /PROD=HIV-1 Tat interactive protein, 60 kDa /DB_XREF=gi:13111803 /UG=Hs.6364 HIV-1 Tat interactive protein, 60 kDa /FL=gb:BC000166.2 gb:U67734.1 BC000166 K(lysine) acetyltransferase 5 KAT5 10524 NM_001206833 /// NM_006388 /// NM_182709 /// NM_182710 /// XM_006718421 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction 209193_at M24779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24779.1 /DEF=Homo sapiens protein kinase-related oncogene (PIM1) mRNA, complete cds. /FEA=mRNA /GEN=PIM1 /PROD=protein kinase /DB_XREF=gi:1066790 /UG=Hs.81170 pim-1 oncogene /FL=gb:M24779.1 gb:M16750.1 gb:M54915.1 gb:NM_002648.1 M24779 Pim-1 proto-oncogene, serine/threonine kinase PIM1 5292 NM_001243186 /// NM_002648 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209194_at BC005334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005334.1 /DEF=Homo sapiens, centrin, EF-hand protein, 2, clone MGC:12421, mRNA, complete cds. /FEA=mRNA /PROD=centrin, EF-hand protein, 2 /DB_XREF=gi:13529121 /UG=Hs.82794 centrin, EF-hand protein, 2 /FL=gb:BC005334.1 gb:NM_004344.1 BC005334 centrin, EF-hand protein, 2 CETN2 1069 NM_004344 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0071942 // XPC complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0032795 // heterotrimeric G-protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209195_s_at AF250226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF250226.1 /DEF=Homo sapiens adenylyl cyclase type VI mRNA, complete cds. /FEA=mRNA /PROD=adenylyl cyclase type VI /DB_XREF=gi:9049782 /UG=Hs.12373 adenylate cyclase 6 /FL=gb:NM_015270.2 gb:AF250226.1 AF250226 adenylate cyclase 6 ADCY6 112 NM_015270 /// NM_020983 /// XM_005268605 /// XM_006719209 /// XM_006719210 /// XM_006719211 /// XM_006719212 /// XM_006719213 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007212 // dopamine receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from direct assay /// 0071870 // cellular response to catecholamine stimulus // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209196_at BC000388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000388.1 /DEF=Homo sapiens, BING4, clone MGC:8435, mRNA, complete cds. /FEA=mRNA /PROD=BING4 /DB_XREF=gi:12653238 /UG=Hs.17930 chromosome 6 open reading frame 11 /FL=gb:BC000388.1 gb:NM_005452.2 BC000388 WD repeat domain 46 WDR46 9277 NM_001164267 /// NM_005452 /// XM_005249481 /// XM_005272908 /// XM_005275064 /// XM_005275320 /// XM_005275491 0005581 // collagen trimer // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209197_at AA626780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA626780 /FEA=EST /DB_XREF=gi:2539167 /DB_XREF=est:ad09f03.s1 /CLONE=IMAGE:877757 /UG=Hs.74554 KIAA0080 protein /FL=gb:BC004291.1 AA626780 synaptotagmin XI SYT11 23208 NM_152280 /// XM_005245014 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209198_s_at BC004291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004291.1 /DEF=Homo sapiens, Similar to synaptotagmin 11, clone MGC:10881, mRNA, complete cds. /FEA=mRNA /PROD=Similar to synaptotagmin 11 /DB_XREF=gi:13279139 /UG=Hs.74554 KIAA0080 protein /FL=gb:BC004291.1 BC004291 synaptotagmin XI SYT11 23208 NM_152280 /// XM_005245014 0006810 // transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209199_s_at N22468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N22468 /FEA=EST /DB_XREF=gi:1128602 /DB_XREF=est:yw34e10.s1 /CLONE=IMAGE:254154 /UG=Hs.78995 MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) /FL=gb:L08895.1 N22468 myocyte enhancer factor 2C MEF2C 4208 NM_001131005 /// NM_001193347 /// NM_001193348 /// NM_001193349 /// NM_001193350 /// NM_002397 /// XM_005248511 /// XM_006714618 /// XM_006714619 /// XM_006714620 /// XM_006714621 /// XM_006714622 /// XM_006714623 /// XM_006714624 /// XM_006714625 0000002 // mitochondrial genome maintenance // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0003138 // primary heart field specification // inferred from sequence or structural similarity /// 0003139 // secondary heart field specification // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003185 // sinoatrial valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from expression pattern /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007507 // heart development // non-traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from expression pattern /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030318 // melanocyte differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042692 // muscle cell differentiation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0045663 // positive regulation of myoblast differentiation // inferred from mutant phenotype /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046928 // regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048311 // mitochondrion distribution // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from mutant phenotype /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0055005 // ventricular cardiac myofibril assembly // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090073 // positive regulation of protein homodimerization activity // inferred from sequence or structural similarity /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from direct assay /// 2000987 // positive regulation of behavioral fear response // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from direct assay 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003680 // AT DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 209200_at AL536517 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL536517 /FEA=EST /DB_XREF=gi:12800010 /DB_XREF=est:AL536517 /CLONE=CS0DF038YH13 (5 prime) /UG=Hs.78995 MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) /FL=gb:L08895.1 AL536517 myocyte enhancer factor 2C MEF2C 4208 NM_001131005 /// NM_001193347 /// NM_001193348 /// NM_001193349 /// NM_001193350 /// NM_002397 /// XM_005248511 /// XM_006714618 /// XM_006714619 /// XM_006714620 /// XM_006714621 /// XM_006714622 /// XM_006714623 /// XM_006714624 /// XM_006714625 0000002 // mitochondrial genome maintenance // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0003138 // primary heart field specification // inferred from sequence or structural similarity /// 0003139 // secondary heart field specification // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003185 // sinoatrial valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from expression pattern /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007507 // heart development // non-traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from expression pattern /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030318 // melanocyte differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042692 // muscle cell differentiation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0045663 // positive regulation of myoblast differentiation // inferred from mutant phenotype /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046928 // regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048311 // mitochondrion distribution // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from mutant phenotype /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0055005 // ventricular cardiac myofibril assembly // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090073 // positive regulation of protein homodimerization activity // inferred from sequence or structural similarity /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from direct assay /// 2000987 // positive regulation of behavioral fear response // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from direct assay 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003680 // AT DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 209201_x_at L01639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L01639.1 /DEF=Human (clone HSY3RR) neuropeptide Y receptor (NPYR) mRNA, complete cds. /FEA=mRNA /GEN=NPYR /PROD=neuropeptide Y receptor /DB_XREF=gi:189313 /UG=Hs.89414 chemokine (C-X-C motif), receptor 4 (fusin) /FL=gb:L01639.1 gb:AF025375.1 gb:M99293.1 gb:L06797.1 gb:NM_003467.1 gb:AF147204.1 L01639 chemokine (C-X-C motif) receptor 4 CXCR4 7852 NM_001008540 /// NM_003467 0000187 // activation of MAPK activity // traceable author statement /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030260 // entry into host cell // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042119 // neutrophil activation // inferred from electronic annotation /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // non-traceable author statement /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // non-traceable author statement /// 0019955 // cytokine binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032027 // myosin light chain binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 209202_s_at AF001690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001690.1 /DEF=Homo sapiens EXT like protein 3 (EXTL3) mRNA, complete cds. /FEA=mRNA /GEN=EXTL3 /PROD=EXT like protein 3 /DB_XREF=gi:2897904 /UG=Hs.9018 exostoses (multiple)-like 3 /FL=gb:AB007042.1 gb:AF001690.1 gb:AB011091.1 gb:AF029231.1 gb:NM_001440.1 gb:AF083551.1 AF001690 exostosin-like glycosyltransferase 3 EXTL3 2137 NM_001440 /// NR_073468 /// NR_073469 /// XM_006716302 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation 0001888 // glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209203_s_at BC002327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002327.1 /DEF=Homo sapiens, ribosomal protein L30, clone MGC:2797, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L30 /DB_XREF=gi:12803052 /UG=Hs.17411 KIAA0699 protein /FL=gb:BC002327.1 BC002327 bicaudal D homolog 2 (Drosophila) BICD2 23299 NM_001003800 /// NM_015250 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0072385 // minus-end-directed organelle transport along microtubule // inferred from sequence or structural similarity /// 0072393 // microtubule anchoring at microtubule organizing center // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity 209204_at AI824831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI824831 /FEA=EST /DB_XREF=gi:5445502 /DB_XREF=est:wb02d08.x1 /CLONE=IMAGE:2304495 /UG=Hs.3844 LIM domain only 4 /FL=gb:BC003600.1 gb:U24576.1 gb:NM_006769.2 AI824831 LIM domain only 4 LMO4 8543 NM_006769 /// XM_005271291 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0021514 // ventral spinal cord interneuron differentiation // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0042659 // regulation of cell fate specification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050865 // regulation of cell activation // inferred from electronic annotation 0005667 // transcription factor complex // inferred from sequence or structural similarity 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209205_s_at BC003600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003600.1 /DEF=Homo sapiens, LIM domain only 4, clone MGC:872, mRNA, complete cds. /FEA=mRNA /PROD=LIM domain only 4 /DB_XREF=gi:13097818 /UG=Hs.3844 LIM domain only 4 /FL=gb:BC003600.1 gb:U24576.1 gb:NM_006769.2 BC003600 LIM domain only 4 LMO4 8543 NM_006769 /// XM_005271291 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0021514 // ventral spinal cord interneuron differentiation // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0042659 // regulation of cell fate specification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050865 // regulation of cell activation // inferred from electronic annotation 0005667 // transcription factor complex // inferred from sequence or structural similarity 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209206_at AV701283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV701283 /FEA=EST /DB_XREF=gi:10717613 /DB_XREF=est:AV701283 /CLONE=ADAAGD06 /UG=Hs.50785 SEC22, vesicle trafficking protein (S. cerevisiae)-like 1 /FL=gb:BC001364.1 gb:AF047442.1 gb:NM_004892.1 AV701283 vesicle-trafficking protein SEC22b-like /// SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) LOC102724364 /// SEC22B 9554 /// 102724364 NM_004892 /// XR_426913 /// XR_431332 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209207_s_at BC001364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001364.1 /DEF=Homo sapiens, SEC22, vesicle trafficking protein (S. cerevisiae)-like 1, clone MGC:1960, mRNA, complete cds. /FEA=mRNA /PROD=SEC22, vesicle trafficking protein (S.cerevisiae)-like 1 /DB_XREF=gi:12655032 /UG=Hs.50785 SEC22, vesicle trafficking protein (S. cerevisiae)-like 1 /FL=gb:BC001364.1 gb:AF047442.1 gb:NM_004892.1 BC001364 vesicle-trafficking protein SEC22b-like /// vesicle-trafficking protein SEC22b-like /// SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) LOC100996517 /// LOC102724364 /// SEC22B 9554 /// 100996517 /// 102724364 NM_004892 /// XR_426825 /// XR_426913 /// XR_431259 /// XR_431332 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209208_at AF059752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF059752.1 /DEF=Homo sapiens clone 015e11 My008 protein mRNA, complete cds. /FEA=mRNA /PROD=My008 protein /DB_XREF=gi:12001955 /UG=Hs.6710 mannose-P-dolichol utilization defect 1 /FL=gb:AF059752.1 gb:BC001898.1 gb:AF038961.1 gb:NM_004870.1 AF059752 mannose-P-dolichol utilization defect 1 MPDU1 9526 NM_004870 /// NR_024603 /// XM_006721597 /// XM_006721598 /// XM_006721599 0006457 // protein folding // non-traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // inferred from genetic interaction 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 209209_s_at AW469573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW469573 /FEA=EST /DB_XREF=gi:7039679 /DB_XREF=est:hd29e09.x1 /CLONE=IMAGE:2910952 /UG=Hs.75260 mitogen inducible 2 /FL=gb:Z24725.1 AW469573 fermitin family member 2 FERMT2 10979 NM_001134999 /// NM_001135000 /// NM_006832 /// XM_005267285 /// XM_006720008 /// XM_006720009 /// XM_006720010 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0033622 // integrin activation // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 209210_s_at Z24725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z24725.1 /DEF=H.sapiens mitogen inducible gene mig-2, complete CDS. /FEA=mRNA /PROD=mitogen inducible gene mig-2 /DB_XREF=gi:505032 /UG=Hs.75260 mitogen inducible 2 /FL=gb:Z24725.1 Z24725 fermitin family member 2 FERMT2 10979 NM_001134999 /// NM_001135000 /// NM_006832 /// XM_005267285 /// XM_006720008 /// XM_006720009 /// XM_006720010 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0033622 // integrin activation // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 209211_at AF132818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF132818.1 /DEF=Homo sapiens colon Kruppel-like factor (CKLF) mRNA, complete cds. /FEA=mRNA /GEN=CKLF /PROD=colon Kruppel-like factor /DB_XREF=gi:6580834 /UG=Hs.84728 Kruppel-like factor 5 (intestinal) /FL=gb:D14520.1 gb:NM_001730.1 gb:AF132818.1 gb:AB030824.1 gb:AF287272.1 AF132818 Kruppel-like factor 5 (intestinal) KLF5 688 NM_001286818 /// NM_001730 /// XM_005266509 /// XM_006719862 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209212_s_at AB030824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030824.1 /DEF=Homo sapiens mRNA for transcription factor BTEB2, complete cds. /FEA=mRNA /GEN=bteb2 /PROD=transcription factor BTEB2 /DB_XREF=gi:8272417 /UG=Hs.84728 Kruppel-like factor 5 (intestinal) /FL=gb:D14520.1 gb:NM_001730.1 gb:AF132818.1 gb:AB030824.1 gb:AF287272.1 AB030824 Kruppel-like factor 5 (intestinal) KLF5 688 NM_001286818 /// NM_001730 /// XM_005266509 /// XM_006719862 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209213_at BC002511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002511.1 /DEF=Homo sapiens, carbonyl reductase 1, clone MGC:1920, mRNA, complete cds. /FEA=mRNA /PROD=carbonyl reductase 1 /DB_XREF=gi:12803380 /UG=Hs.88778 carbonyl reductase 1 /FL=gb:BC002511.1 gb:J04056.1 gb:NM_001757.1 BC002511 carbonyl reductase 1 CBR1 873 NM_001286789 /// NM_001757 0008152 // metabolic process // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042373 // vitamin K metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004090 // carbonyl reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0047021 // 15-hydroxyprostaglandin dehydrogenase (NADP+) activity // inferred from electronic annotation /// 0050221 // prostaglandin-E2 9-reductase activity // inferred from electronic annotation 209214_s_at BC004817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004817.1 /DEF=Homo sapiens, Ewing sarcoma breakpoint region 1, clone MGC:5432, mRNA, complete cds. /FEA=mRNA /PROD=Ewing sarcoma breakpoint region 1 /DB_XREF=gi:13435962 /UG=Hs.129953 Ewing sarcoma breakpoint region 1 /FL=gb:BC004817.1 gb:NM_005243.1 BC004817 EWS RNA-binding protein 1 EWSR1 2130 NM_001163285 /// NM_001163286 /// NM_001163287 /// NM_005243 /// NM_013986 /// XM_005261389 /// XM_005261390 /// XM_006724166 /// XM_006724167 /// XR_430403 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209215_at L11669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11669.1 /DEF=Human tetracycline transporter-like protein mRNA, complete cds. /FEA=mRNA /PROD=tetracycline transporter-like protein /DB_XREF=gi:307501 /UG=Hs.157145 tetracycline transporter-like protein /FL=gb:L11669.1 gb:NM_001120.1 L11669 major facilitator superfamily domain containing 10 MFSD10 10227 NM_001120 /// NM_001146069 /// XM_005247927 /// XM_005247928 /// XR_427465 /// XR_427466 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015904 // tetracycline transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008493 // tetracycline transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 209216_at BC000464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000464.1 /DEF=Homo sapiens, JM5 protein, clone MGC:8542, mRNA, complete cds. /FEA=mRNA /PROD=JM5 protein /DB_XREF=gi:12653388 /UG=Hs.21753 JM5 protein /FL=gb:BC000464.1 gb:BC003037.1 gb:AJ005897.1 gb:NM_007075.1 BC000464 WD repeat domain 45 WDR45 11152 NM_001029896 /// NM_007075 0000045 // autophagic vacuole assembly // not recorded /// 0006914 // autophagy // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // not recorded /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // not recorded 209217_s_at BC000464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000464.1 /DEF=Homo sapiens, JM5 protein, clone MGC:8542, mRNA, complete cds. /FEA=mRNA /PROD=JM5 protein /DB_XREF=gi:12653388 /UG=Hs.21753 JM5 protein /FL=gb:BC000464.1 gb:BC003037.1 gb:AJ005897.1 gb:NM_007075.1 BC000464 WD repeat domain 45 WDR45 11152 NM_001029896 /// NM_007075 0000045 // autophagic vacuole assembly // not recorded /// 0006914 // autophagy // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // not recorded /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // not recorded 209218_at AF098865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098865.1 /DEF=Homo sapiens squalene epoxidase (ERG1) mRNA, complete cds. /FEA=mRNA /GEN=ERG1 /PROD=squalene epoxidase /DB_XREF=gi:4204674 /UG=Hs.71465 squalene epoxidase /FL=gb:D78130.1 gb:AF098865.1 gb:NM_003129.2 AF098865 squalene epoxidase SQLE 6713 NM_003129 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004506 // squalene monooxygenase activity // non-traceable author statement /// 0004506 // squalene monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 209219_at L03411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L03411.1 /DEF=Human RD protein (RD) mRNA, complete cds. /FEA=mRNA /GEN=RD /PROD=RD protein /DB_XREF=gi:190973 /UG=Hs.106061 RD RNA-binding protein /FL=gb:L03411.1 gb:NM_002904.1 L03411 microRNA 1236 /// negative elongation factor complex member E MIR1236 /// NELFE 7936 /// 100302242 NM_002904 /// NR_031601 /// XM_006715205 /// XM_006725521 /// XM_006725739 /// XM_006725936 /// XM_006726037 /// XM_006726125 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209220_at L47125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L47125.1 /DEF=Homo sapiens (chromosome X) glypican (GPC3) mRNA, complete cds. /FEA=mRNA /GEN=GPC3 /PROD=glypican /DB_XREF=gi:1237180 /UG=Hs.119651 glypican 3 /FL=gb:L47125.1 gb:U50410.1 gb:NM_004484.2 gb:L47176.1 L47125 glypican 3 GPC3 2719 NM_001164617 /// NM_001164618 /// NM_001164619 /// NM_004484 0001523 // retinoid metabolic process // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010171 // body morphogenesis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045926 // negative regulation of growth // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060976 // coronary vasculature development // inferred from electronic annotation /// 0072111 // cell proliferation involved in kidney development // inferred from electronic annotation /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from sequence or structural similarity /// 0072180 // mesonephric duct morphogenesis // inferred from electronic annotation /// 0072203 // cell proliferation involved in metanephros development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0060422 // peptidyl-dipeptidase inhibitor activity // inferred from direct assay 209221_s_at AI753638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI753638 /FEA=EST /DB_XREF=gi:5131902 /DB_XREF=est:cr13c02.x1 /CLONE=HBMSC_cr13c02 /UG=Hs.15519 KIAA0772 gene product /FL=gb:BC000296.1 gb:BC004455.1 AI753638 oxysterol binding protein-like 2 OSBPL2 9885 NM_001278649 /// NM_014835 /// NM_144498 /// XM_005260625 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 209222_s_at BC000296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000296.1 /DEF=Homo sapiens, Similar to KIAA0772 gene product, clone MGC:8342, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0772 gene product /DB_XREF=gi:12653062 /UG=Hs.15519 KIAA0772 gene product /FL=gb:BC000296.1 gb:BC004455.1 BC000296 oxysterol binding protein-like 2 OSBPL2 9885 NM_001278649 /// NM_014835 /// NM_144498 /// XM_005260625 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 209223_at BF434335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF434335 /FEA=EST /DB_XREF=gi:11446623 /DB_XREF=est:7o95g09.x1 /CLONE=IMAGE:3644344 /UG=Hs.163867 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8) /FL=gb:BC003674.1 gb:AF047185.1 gb:NM_002488.1 gb:AF077029.1 BF434335 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa NDUFA2 4695 NM_001185012 /// NM_002488 /// NR_033697 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 209224_s_at BC003674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003674.1 /DEF=Homo sapiens, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8), clone MGC:12315, mRNA, complete cds. /FEA=mRNA /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 2 (8kD, B8) /DB_XREF=gi:13277539 /UG=Hs.163867 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8) /FL=gb:BC003674.1 gb:AF047185.1 gb:NM_002488.1 gb:AF077029.1 BC003674 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa NDUFA2 4695 NM_001185012 /// NM_002488 /// NR_033697 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 209225_x_at AI653355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653355 /FEA=EST /DB_XREF=gi:4737334 /DB_XREF=est:wb45b07.x1 /CLONE=IMAGE:2308597 /UG=Hs.168075 karyopherin (importin) beta 2 /FL=gb:U72069.1 gb:U72395.1 AI653355 transportin 1 TNPO1 3842 NM_002270 /// NM_153188 /// XM_005248500 /// XM_005248501 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209226_s_at U72069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U72069.1 /DEF=Human karyopherin beta2 mRNA, complete cds. /FEA=mRNA /PROD=karyopherin beta2 /DB_XREF=gi:1657775 /UG=Hs.168075 karyopherin (importin) beta 2 /FL=gb:U72069.1 gb:U72395.1 U72069 transportin 1 TNPO1 3842 NM_002270 /// NM_153188 /// XM_005248500 /// XM_005248501 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209227_at AU158251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158251 /FEA=EST /DB_XREF=gi:11019772 /DB_XREF=est:AU158251 /CLONE=PLACE1011740 /UG=Hs.71119 Putative prostate cancer tumor suppressor /FL=gb:U42349.1 gb:NM_006765.1 AU158251 tumor suppressor candidate 3 TUSC3 7991 NM_006765 /// NM_178234 /// XM_005273646 /// XM_005273647 /// XM_005273648 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from genetic interaction /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype 209228_x_at U42349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U42349.1 /DEF=Human N33 mRNA, complete cds. /FEA=mRNA /GEN=N33 /DB_XREF=gi:1353672 /UG=Hs.71119 Putative prostate cancer tumor suppressor /FL=gb:U42349.1 gb:NM_006765.1 U42349 tumor suppressor candidate 3 TUSC3 7991 NM_006765 /// NM_178234 /// XM_005273646 /// XM_005273647 /// XM_005273648 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from genetic interaction /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype 209229_s_at BC002799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002799.1 /DEF=Homo sapiens, KIAA1115 protein, clone MGC:3534, mRNA, complete cds. /FEA=mRNA /PROD=KIAA1115 protein /DB_XREF=gi:12803904 /UG=Hs.72172 KIAA1115 protein /FL=gb:BC002799.1 BC002799 protein phosphatase 6, regulatory subunit 1 PPP6R1 22870 NM_014931 /// XM_005258669 /// XM_005258670 /// XM_006723090 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 209230_s_at AF135266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF135266.1 /DEF=Homo sapiens p8 protein homolog (COM1) mRNA, complete cds. /FEA=mRNA /GEN=COM1 /PROD=p8 protein homolog /DB_XREF=gi:5732669 /UG=Hs.8603 p8 protein (candidate of metastasis 1) /FL=gb:AF069073.1 gb:AF135266.1 gb:NM_012385.1 AF135266 nuclear protein, transcriptional regulator, 1 NUPR1 26471 NM_001042483 /// NM_012385 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0031401 // positive regulation of protein modification process // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 2000194 // regulation of female gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 209231_s_at AI038068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI038068 /FEA=EST /DB_XREF=gi:3277262 /DB_XREF=est:ox21b12.x1 /CLONE=IMAGE:1656959 /UG=Hs.111429 Homo sapiens, dynactin 4, clone MGC:3248, mRNA, complete cds /FL=gb:BC004191.1 AI038068 dynactin 5 (p25) DCTN5 84516 NM_001199011 /// NM_001199743 /// NM_032486 /// NR_037573 /// XR_243320 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 209232_s_at BC004191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004191.1 /DEF=Homo sapiens, dynactin 4, clone MGC:3248, mRNA, complete cds. /FEA=mRNA /PROD=dynactin 4 /DB_XREF=gi:13278857 /UG=Hs.111429 Homo sapiens, dynactin 4, clone MGC:3248, mRNA, complete cds /FL=gb:BC004191.1 BC004191 dynactin 5 (p25) DCTN5 84516 NM_001199011 /// NM_001199743 /// NM_032486 /// NR_037573 /// XR_243320 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 209233_at U72514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U72514.1 /DEF=Human C2f mRNA, complete cds. /FEA=mRNA /GEN=C2f /PROD=C2f /DB_XREF=gi:2276395 /UG=Hs.12045 putative protein /FL=gb:U72514.1 U72514 EMG1 N1-specific pseudouridine methyltransferase EMG1 10436 NM_006331 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0031167 // rRNA methylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042274 // ribosomal small subunit biogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003723 // RNA binding // inferred from sequence or structural similarity /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070037 // rRNA (pseudouridine) methyltransferase activity // inferred from direct assay 209234_at BF939474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939474 /FEA=EST /DB_XREF=gi:12356794 /DB_XREF=est:nac76d12.x1 /CLONE=IMAGE:3440303 /UG=Hs.129908 KIAA0591 protein /FL=gb:BC001415.1 BF939474 kinesin family member 1B KIF1B 23095 NM_015074 /// NM_183416 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from sequence or structural similarity /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007274 // neuromuscular synaptic transmission // inferred from sequence or structural similarity /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030705 // cytoskeleton-dependent intracellular transport // inferred from sequence or structural similarity /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from sequence or structural similarity /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0019894 // kinesin binding // traceable author statement 209235_at AL031600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031600 /DEF=Human DNA sequence from clone 390E6 on chromosome 16. Contains the 3 part of the CLCN7 gene for chloride channel 7, ESTs, a GSS and four putative CpG islands /FEA=mRNA /DB_XREF=gi:4826481 /UG=Hs.80768 chloride channel 7 /FL=gb:AF224741.1 AL031600 chloride channel, voltage-sensitive 7 CLCN7 1186 NM_001114331 /// NM_001287 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 209236_at AL389886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL389886 /DEF=Human DNA sequence from clone RP1-237C24 on chromosome 20 Contains the 3 end of the SLC23A1 gene encoding solute carrier family 23 member1 (nucleobase transporters), ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:10086152 /UG=Hs.82042 solute carrier family 23 (nucleobase transporters), member 1 /FL=gb:AF058319.1 gb:NM_005116.1 gb:AF164142.1 AL389886 solute carrier family 23 (ascorbic acid transporter), member 2 SLC23A2 9962 NM_005116 /// NM_203327 /// XM_005260904 /// XM_006723671 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0015851 // nucleobase transport // traceable author statement /// 0015882 // L-ascorbic acid transport // inferred from direct assay /// 0015993 // molecular hydrogen transport // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0035461 // vitamin transmembrane transport // inferred from direct assay /// 0035461 // vitamin transmembrane transport // inferred from electronic annotation /// 0035461 // vitamin transmembrane transport // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070904 // transepithelial L-ascorbic acid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0008520 // L-ascorbate:sodium symporter activity // inferred from electronic annotation /// 0008523 // sodium-dependent multivitamin transmembrane transporter activity // non-traceable author statement /// 0015205 // nucleobase transmembrane transporter activity // traceable author statement /// 0015229 // L-ascorbic acid transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0070890 // sodium-dependent L-ascorbate transmembrane transporter activity // inferred from direct assay 209237_s_at AF164142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF164142.1 /DEF=Homo sapiens sodium-dependent vitamin transporter 2 (SVCT2) mRNA, complete cds. /FEA=mRNA /GEN=SVCT2 /PROD=sodium-dependent vitamin transporter 2 /DB_XREF=gi:8886523 /UG=Hs.82042 solute carrier family 23 (nucleobase transporters), member 1 /FL=gb:AF058319.1 gb:NM_005116.1 gb:AF164142.1 AF164142 solute carrier family 23 (ascorbic acid transporter), member 2 SLC23A2 9962 NM_005116 /// NM_203327 /// XM_005260904 /// XM_006723671 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0015851 // nucleobase transport // traceable author statement /// 0015882 // L-ascorbic acid transport // inferred from direct assay /// 0015993 // molecular hydrogen transport // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0035461 // vitamin transmembrane transport // inferred from direct assay /// 0035461 // vitamin transmembrane transport // inferred from electronic annotation /// 0035461 // vitamin transmembrane transport // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070904 // transepithelial L-ascorbic acid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0008520 // L-ascorbate:sodium symporter activity // inferred from electronic annotation /// 0008523 // sodium-dependent multivitamin transmembrane transporter activity // non-traceable author statement /// 0015205 // nucleobase transmembrane transporter activity // traceable author statement /// 0015229 // L-ascorbic acid transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0070890 // sodium-dependent L-ascorbate transmembrane transporter activity // inferred from direct assay 209238_at BE966922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966922 /FEA=EST /DB_XREF=gi:11772839 /DB_XREF=est:601660942R1 /CLONE=IMAGE:3915610 /UG=Hs.82240 syntaxin 3A /FL=gb:AJ002076.1 gb:NM_004177.1 gb:U32315.1 BE966922 syntaxin 3 STX3 6809 NM_001178040 /// NM_004177 /// XM_005274195 /// XM_005274196 /// XM_005274198 /// XM_005274199 /// XM_005274200 /// XM_006718672 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0061025 // membrane fusion // inferred from electronic annotation 0005773 // vacuole // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0050544 // arachidonic acid binding // inferred from sequence or structural similarity 209239_at M55643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55643.1 /DEF=Human factor KBF1 mRNA, complete cds. /FEA=mRNA /GEN=NF-kappa-B /PROD=factor KBF1 /DB_XREF=gi:189179 /UG=Hs.83428 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) /FL=gb:NM_003998.1 gb:M58603.1 gb:M55643.1 M55643 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 NFKB1 4790 NM_001165412 /// NM_003998 /// XM_005263029 /// XM_006714229 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001818 // negative regulation of cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010884 // positive regulation of lipid storage // inferred by curator /// 0010956 // negative regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0010957 // negative regulation of vitamin D biosynthetic process // inferred by curator /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0032269 // negative regulation of cellular protein metabolic process // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred by curator /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045083 // negative regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071316 // cellular response to nicotine // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071354 // cellular response to interleukin-6 // inferred from mutant phenotype /// 0071375 // cellular response to peptide hormone stimulus // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000630 // positive regulation of miRNA metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0033256 // I-kappaB/NF-kappaB complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from direct assay /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 209240_at AF070560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070560.1 /DEF=Homo sapiens clone 24689 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387927 /UG=Hs.100293 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) /FL=gb:AF223393.1 AF070560 O-linked N-acetylglucosamine (GlcNAc) transferase OGT 8473 NM_003605 /// NM_181672 /// NM_181673 /// XM_005262308 /// XM_006724714 0006110 // regulation of glycolytic process // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from sequence or structural similarity 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070688 // MLL5-L complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay /// 0097363 // protein O-GlcNAc transferase activity // inferred from sequence or structural similarity 209241_x_at AB041926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB041926.1 /DEF=Homo sapiens mRNA for GCK family kinase MINK-2, complete cds. /FEA=mRNA /GEN=MINK /PROD=GCK family kinase MINK-2 /DB_XREF=gi:7637420 /UG=Hs.112028 MisshapenNIK-related kinase /FL=gb:AB041926.1 AB041926 misshapen-like kinase 1 MINK1 50488 NM_001024937 /// NM_015716 /// NM_153827 /// NM_170663 /// XM_005256664 /// XM_005256665 /// XM_005256666 /// XM_006721530 /// XM_006721531 /// XM_006721532 /// XM_006721533 /// XM_006721534 /// XM_006721535 /// XM_006721536 /// XM_006721537 /// XM_006721538 0001952 // regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209242_at AL042588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL042588 /FEA=EST /DB_XREF=gi:5935496 /DB_XREF=est:DKFZp434K2121_r1 /CLONE=DKFZp434K2121 /UG=Hs.139033 paternally expressed 3 /FL=gb:AF208967.1 AL042588 paternally expressed 3 PEG3 5178 NM_001146184 /// NM_001146185 /// NM_001146186 /// NM_001146187 /// NM_006210 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209243_s_at AF208967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF208967.1 /DEF=Homo sapiens Kruppel-type zinc finger protein (PEG3) mRNA, alternative splice form 1, complete cds. /FEA=mRNA /GEN=PEG3 /PROD=Kruppel-type zinc finger protein /DB_XREF=gi:11494019 /UG=Hs.139033 paternally expressed 3 /FL=gb:AF208967.1 AF208967 paternally expressed 3 PEG3 5178 NM_001146184 /// NM_001146185 /// NM_001146186 /// NM_001146187 /// NM_006210 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209244_s_at BE885926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE885926 /FEA=EST /DB_XREF=gi:10339732 /DB_XREF=est:601507557F1 /CLONE=IMAGE:3909015 /UG=Hs.139648 KIAA0706 gene product /FL=gb:AB014606.1 BE885926 kinesin family member 1C KIF1C 10749 NM_006612 /// XM_005256424 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209245_s_at AB014606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014606.1 /DEF=Homo sapiens mRNA for KIAA0706 protein, complete cds. /FEA=mRNA /GEN=KIAA0706 /PROD=KIAA0706 protein /DB_XREF=gi:3327225 /UG=Hs.139648 KIAA0706 gene product /FL=gb:AB014606.1 AB014606 209246_at AF261091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF261091.1 /DEF=Homo sapiens iron inhibited ABC transporter 2 mRNA, complete cds. /FEA=mRNA /PROD=iron inhibited ABC transporter 2 /DB_XREF=gi:10179833 /UG=Hs.153612 ATP-binding cassette, sub-family F (GCN20), member 2 /FL=gb:AF261091.1 gb:AF261092.1 gb:BC001661.1 gb:AF091073.1 AF261091 ATP-binding cassette, sub-family F (GCN20), member 2 ABCF2 10061 NM_005692 /// NM_007189 /// XM_005249931 /// XM_006715824 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209247_s_at BC001661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001661.1 /DEF=Homo sapiens, ATP-binding cassette, sub-family F (GCN20), member 2, clone MGC:1425, mRNA, complete cds. /FEA=mRNA /PROD=ATP-binding cassette, sub-family F (GCN20),member 2 /DB_XREF=gi:12804500 /UG=Hs.153612 ATP-binding cassette, sub-family F (GCN20), member 2 /FL=gb:AF261091.1 gb:AF261092.1 gb:BC001661.1 gb:AF091073.1 BC001661 ATP-binding cassette, sub-family F (GCN20), member 2 ABCF2 10061 NM_005692 /// NM_007189 /// XM_005249931 /// XM_006715824 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209248_at AL136713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136713.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566K113 (from clone DKFZp566K113); complete cds. /FEA=mRNA /GEN=DKFZp566K113 /PROD=hypothetical protein /DB_XREF=gi:12052945 /UG=Hs.182470 PTD010 protein /FL=gb:AF060923.1 gb:AL136713.1 gb:AF131820.1 gb:AF078863.1 gb:AB009685.1 gb:NM_014394.1 AL136713 growth hormone inducible transmembrane protein GHITM 27069 NM_014394 0006915 // apoptotic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209249_s_at AF131820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF131820.1 /DEF=Homo sapiens clone 25077 mRNA sequence, complete cds. /FEA=mRNA /PROD=Unknown /DB_XREF=gi:4406655 /UG=Hs.182470 PTD010 protein /FL=gb:AF060923.1 gb:AL136713.1 gb:AF131820.1 gb:AF078863.1 gb:AB009685.1 gb:NM_014394.1 AF131820 growth hormone inducible transmembrane protein GHITM 27069 NM_014394 0006915 // apoptotic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209250_at BC000961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000961.2 /DEF=Homo sapiens, degenerative spermatocyte (homolog Drosophila; lipid desaturase), clone MGC:5079, mRNA, complete cds. /FEA=mRNA /PROD=degenerative spermatocyte (homolog Drosophila;lipid desaturase) /DB_XREF=gi:12803018 /UG=Hs.185973 degenerative spermatocyte (homolog Drosophila; lipid desaturase) /FL=gb:BC000961.2 BC000961 delta(4)-desaturase, sphingolipid 1 DEGS1 8560 NM_003676 /// NM_144780 /// XM_006711839 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation 209251_x_at BC004949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004949.1 /DEF=Homo sapiens, tubulin alpha 6, clone MGC:10851, mRNA, complete cds. /FEA=mRNA /PROD=tubulin alpha 6 /DB_XREF=gi:13436316 /UG=Hs.272897 Tubulin, alpha, brain-specific /FL=gb:BC004949.1 BC004949 tubulin, alpha 1c TUBA1C 84790 NM_032704 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 209252_at U18937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18937.1 /DEF=Human histidyl-tRNA synthetase homolog (HO3) mRNA, complete cds. /FEA=mRNA /GEN=HO3 /PROD=histidyl-tRNA synthetase homologue /DB_XREF=gi:899108 /UG=Hs.278507 histidyl-tRNA synthetase-like /FL=gb:U18937.1 U18937 histidyl-tRNA synthetase 2, mitochondrial HARS2 23438 NM_001278731 /// NM_001278732 /// NM_012208 /// XM_006714777 /// XM_006714778 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006427 // histidyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004821 // histidine-tRNA ligase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209253_at AF037261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037261.1 /DEF=Homo sapiens SH3-containing adaptor molecule-1 mRNA, complete cds. /FEA=mRNA /PROD=SH3-containing adaptor molecule-1 /DB_XREF=gi:3004947 /UG=Hs.33787 vinexin beta (SH3-containing adaptor molecule-1) /FL=gb:AF037261.1 AF037261 sorbin and SH3 domain containing 3 SORBS3 10174 NM_001018003 /// NM_005775 /// XM_005273370 /// XM_005273371 /// XM_006716266 /// XM_006716267 /// XM_006716268 /// XM_006716269 /// XM_006716270 /// XM_006716271 /// XR_428299 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051495 // positive regulation of cytoskeleton organization // non-traceable author statement /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction 209254_at AI808625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI808625 /FEA=EST /DB_XREF=gi:5395191 /DB_XREF=est:wf56f12.x1 /CLONE=IMAGE:2359631 /UG=Hs.192966 KIAA0265 protein /FL=gb:AF277177.1 AI808625 kelch domain containing 10 KLHDC10 23008 NM_014997 /// XM_005250233 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209255_at D87454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87454.1 /DEF=Human mRNA for KIAA0265 gene, partial cds. /FEA=mRNA /GEN=KIAA0265 /DB_XREF=gi:1665796 /UG=Hs.192966 KIAA0265 protein /FL=gb:AF277177.1 D87454 kelch domain containing 10 KLHDC10 23008 NM_014997 /// XM_005250233 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209256_s_at AF277177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF277177.1 /DEF=Homo sapiens PNAS-119 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-119 /DB_XREF=gi:12751084 /UG=Hs.192966 KIAA0265 protein /FL=gb:AF277177.1 AF277177 kelch domain containing 10 KLHDC10 23008 NM_014997 /// XM_005250233 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209257_s_at BF795297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF795297 /FEA=EST /DB_XREF=gi:12100351 /DB_XREF=est:602256270F1 /CLONE=IMAGE:4339721 /UG=Hs.24485 chondroitin sulfate proteoglycan 6 (bamacan) /FL=gb:AF020043.1 gb:NM_005445.1 gb:AF067163.1 BF795297 structural maintenance of chromosomes 3 SMC3 9126 NM_005445 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from expression pattern /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007062 // sister chromatid cohesion // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000800 // lateral element // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // non-traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030893 // meiotic cohesin complex // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 209258_s_at AI373676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI373676 /FEA=EST /DB_XREF=gi:4153542 /DB_XREF=est:qz53h11.x1 /CLONE=IMAGE:2030661 /UG=Hs.24485 chondroitin sulfate proteoglycan 6 (bamacan) /FL=gb:AF020043.1 gb:NM_005445.1 gb:AF067163.1 AI373676 structural maintenance of chromosomes 3 SMC3 9126 NM_005445 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from expression pattern /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007062 // sister chromatid cohesion // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000800 // lateral element // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // non-traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030893 // meiotic cohesin complex // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 209259_s_at AF020043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020043.1 /DEF=Homo sapiens chromosome-associated polypeptide (HCAP) mRNA, complete cds. /FEA=mRNA /GEN=HCAP /PROD=chromosome-associated polypeptide /DB_XREF=gi:3089367 /UG=Hs.24485 chondroitin sulfate proteoglycan 6 (bamacan) /FL=gb:AF020043.1 gb:NM_005445.1 gb:AF067163.1 AF020043 structural maintenance of chromosomes 3 SMC3 9126 NM_005445 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from expression pattern /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007062 // sister chromatid cohesion // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000800 // lateral element // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // non-traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030893 // meiotic cohesin complex // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 209260_at BC000329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000329.1 /DEF=Homo sapiens, stratifin, clone MGC:8516, mRNA, complete cds. /FEA=mRNA /PROD=stratifin /DB_XREF=gi:12653124 /UG=Hs.184510 stratifin /FL=gb:BC000329.1 gb:BC000995.2 gb:BC002995.1 gb:M93010.1 gb:AF029082.1 gb:NM_006142.1 BC000329 stratifin SFN 2810 NM_006142 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045606 // positive regulation of epidermal cell differentiation // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 209261_s_at BF000629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF000629 /FEA=EST /DB_XREF=gi:10700904 /DB_XREF=est:7h33g12.x1 /CLONE=IMAGE:3317830 /UG=Hs.239752 nuclear receptor subfamily 2, group F, member 6 /FL=gb:BC002669.1 gb:NM_005234.1 BF000629 nuclear receptor subfamily 2, group F, member 6 NR2F6 2063 NM_005234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043153 // entrainment of circadian clock by photoperiod // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209262_s_at BC002669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002669.1 /DEF=Homo sapiens, nuclear receptor subfamily 2, group F, member 6, clone MGC:4277, mRNA, complete cds. /FEA=mRNA /PROD=nuclear receptor subfamily 2, group F, member 6 /DB_XREF=gi:12803666 /UG=Hs.239752 nuclear receptor subfamily 2, group F, member 6 /FL=gb:BC002669.1 gb:NM_005234.1 BC002669 nuclear receptor subfamily 2, group F, member 6 NR2F6 2063 NM_005234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043153 // entrainment of circadian clock by photoperiod // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209263_x_at BC000389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000389.1 /DEF=Homo sapiens, transmembrane 4 superfamily member 7, clone MGC:8437, mRNA, complete cds. /FEA=mRNA /PROD=transmembrane 4 superfamily member 7 /DB_XREF=gi:12653240 /UG=Hs.26518 transmembrane 4 superfamily member 7 /FL=gb:BC000389.1 gb:AF022813.1 gb:AF054841.1 gb:NM_003271.1 BC000389 tetraspanin 4 TSPAN4 7106 NM_001025234 /// NM_001025235 /// NM_001025236 /// NM_001025237 /// NM_001025238 /// NM_001025239 /// NM_003271 /// XM_005253102 /// XM_005253104 /// XM_006718287 0006461 // protein complex assembly // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay 0003823 // antigen binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 209264_s_at AF054841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054841.1 /DEF=Homo sapiens tetraspan TM4SF (TSPAN-4) mRNA, complete cds. /FEA=mRNA /GEN=TSPAN-4 /PROD=tetraspan TM4SF /DB_XREF=gi:2997746 /UG=Hs.26518 transmembrane 4 superfamily member 7 /FL=gb:BC000389.1 gb:AF022813.1 gb:AF054841.1 gb:NM_003271.1 AF054841 tetraspanin 4 TSPAN4 7106 NM_001025234 /// NM_001025235 /// NM_001025236 /// NM_001025237 /// NM_001025238 /// NM_001025239 /// NM_003271 /// XM_005253102 /// XM_005253104 /// XM_006718287 0006461 // protein complex assembly // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay 0003823 // antigen binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 209265_s_at BC001650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001650.1 /DEF=Homo sapiens, Similar to putative methyltransferase, clone MGC:2708, mRNA, complete cds. /FEA=mRNA /PROD=Similar to putative methyltransferase /DB_XREF=gi:12804482 /UG=Hs.268149 putative methyltransferase /FL=gb:BC003031.1 gb:BC001650.1 gb:NM_019852.1 BC001650 methyltransferase like 3 METTL3 56339 NM_019852 /// XM_006720206 0001510 // RNA methylation // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061157 // mRNA destabilization // inferred from sequence or structural similarity /// 0080009 // mRNA methylation // inferred from direct assay /// 0080009 // mRNA methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016422 // mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity // inferred from direct assay /// 0016422 // mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation 209266_s_at AW134794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134794 /FEA=EST /DB_XREF=gi:6138340 /DB_XREF=est:UI-H-BI1-abs-a-06-0-UI.s1 /CLONE=IMAGE:2712850 /UG=Hs.284205 up-regulated by BCG-CWS /FL=gb:AB040120.1 AW134794 solute carrier family 39 (zinc transporter), member 8 SLC39A8 64116 NM_001135146 /// NM_001135147 /// NM_001135148 /// NM_022154 /// XM_005263177 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from mutant phenotype /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from direct assay 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 209267_s_at AB040120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB040120.1 /DEF=Homo sapiens mRNA for BCG induced integral membrane protein BIGMo-103, complete cds. /FEA=mRNA /GEN=BIGMo-103 /PROD=BCG induced integral membrane protein BIGMo-103 /DB_XREF=gi:12657580 /UG=Hs.284205 up-regulated by BCG-CWS /FL=gb:AB040120.1 AB040120 solute carrier family 39 (zinc transporter), member 8 SLC39A8 64116 NM_001135146 /// NM_001135147 /// NM_001135148 /// NM_022154 /// XM_005263177 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from mutant phenotype /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from direct assay 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 209268_at AF165513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF165513.1 /DEF=Homo sapiens vacuolar protein sorting 45 isoform (VPS45) mRNA, complete cds. /FEA=mRNA /GEN=VPS45 /PROD=vacuolar protein sorting 45 isoform /DB_XREF=gi:9294732 /UG=Hs.6650 vacuolar protein sorting 45B (yeast homolog) /FL=gb:NM_007259.1 gb:AF165513.1 AF165513 vacuolar protein sorting 45 homolog (S. cerevisiae) VPS45 11311 NM_001279353 /// NM_001279354 /// NM_001279355 /// NM_007259 /// NR_103998 /// XM_006711142 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 209269_s_at AW450910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450910 /FEA=EST /DB_XREF=gi:6991686 /DB_XREF=est:UI-H-BI3-all-e-01-0-UI.s1 /CLONE=IMAGE:2737225 /UG=Hs.74101 spleen tyrosine kinase /FL=gb:BC002962.1 gb:BC001645.1 gb:L28824.1 AW450910 spleen tyrosine kinase SYK 6850 NM_001135052 /// NM_001174167 /// NM_001174168 /// NM_003177 /// XM_005252147 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001820 // serotonin secretion // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002281 // macrophage activation involved in immune response // inferred from sequence or structural similarity /// 0002283 // neutrophil activation involved in immune response // inferred from sequence or structural similarity /// 0002366 // leukocyte activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002554 // serotonin secretion by platelet // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010543 // regulation of platelet activation // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0032928 // regulation of superoxide anion generation // inferred from sequence or structural similarity /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0043313 // regulation of neutrophil degranulation // inferred from sequence or structural similarity /// 0043366 // beta selection // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045401 // positive regulation of interleukin-3 biosynthetic process // inferred from electronic annotation /// 0045425 // positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050764 // regulation of phagocytosis // inferred from sequence or structural similarity /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071226 // cellular response to molecule of fungal origin // inferred from sequence or structural similarity /// 0090237 // regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0019815 // B cell receptor complex // inferred from electronic annotation /// 0032009 // early phagosome // inferred from sequence or structural similarity /// 0042101 // T cell receptor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 209270_at L25541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L25541.1 /DEF=Human laminin S B3 chain (LAMB3) mRNA, complete cds. /FEA=mRNA /GEN=LAMB3 /PROD=laminin S B3 chain /DB_XREF=gi:510702 /UG=Hs.75517 laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD)) /FL=gb:D37766.1 gb:NM_000228.1 gb:L25541.1 L25541 laminin, beta 3 LAMB3 3914 NM_000228 /// NM_001017402 /// NM_001127641 /// XM_005273124 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 209271_at AB032251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB032251.1 /DEF=Homo sapiens BPTF mRNA for bromodomain PHD finger transcription factor, complete cds. /FEA=mRNA /GEN=BPTF /PROD=bromodomain PHD finger transcription factor /DB_XREF=gi:6683491 /UG=Hs.99872 fetal Alzheimer antigen /FL=gb:AB032251.1 AB032251 bromodomain PHD finger transcription factor BPTF 2186 NM_004459 /// NM_182641 /// XM_005257150 /// XM_005257151 /// XM_005257152 /// XM_005257153 /// XM_005257154 /// XM_005257155 /// XM_005257156 /// XM_005257157 /// XM_005257158 /// XM_005257159 /// XM_005257160 /// XM_005257161 /// XM_005257162 /// XM_006721770 /// XM_006721771 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007492 // endoderm development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 209272_at AF045451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF045451.1 /DEF=Homo sapiens transcriptional regulatory protein p54 mRNA, complete cds. /FEA=mRNA /PROD=transcriptional regulatory protein p54 /DB_XREF=gi:3282822 /UG=Hs.107474 NGFI-A binding protein 1 (ERG1 binding protein 1) /FL=gb:AF045451.1 AF045451 NGFI-A binding protein 1 (EGR1 binding protein 1) NAB1 4664 NM_005966 /// XM_005246579 /// XM_005246580 /// XM_005246581 /// XM_005246582 /// XM_005246583 /// XM_005246584 /// XM_005246585 /// XM_005246586 /// XM_005246587 /// XM_006712540 0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0008134 // transcription factor binding // inferred from electronic annotation 209273_s_at BG387555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG387555 /FEA=EST /DB_XREF=gi:13281001 /DB_XREF=est:602412371F1 /CLONE=IMAGE:4521017 /UG=Hs.177776 hypothetical protein MGC4276 similar to CG8198 /FL=gb:AF284752.1 gb:BC002675.1 BG387555 iron-sulfur cluster assembly 1 ISCA1 81689 NM_030940 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 209274_s_at BC002675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002675.1 /DEF=Homo sapiens, Similar to CG8198 gene product, clone MGC:4276, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG8198 gene product /DB_XREF=gi:12803678 /UG=Hs.177776 hypothetical protein MGC4276 similar to CG8198 /FL=gb:AF284752.1 gb:BC002675.1 BC002675 iron-sulfur cluster assembly 1 ISCA1 81689 NM_030940 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 209275_s_at AF015593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015593.1 /DEF=Homo sapiens CLN3 protein (CLN3) mRNA, complete cds. /FEA=mRNA /GEN=CLN3 /PROD=CLN3 protein /DB_XREF=gi:4102728 /UG=Hs.194660 ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) /FL=gb:U32680.1 gb:BC002394.1 gb:BC004433.1 gb:AF015593.1 gb:NM_000086.1 gb:AF078169.1 gb:AF077956.1 gb:AF077957.1 gb:AF077958.1 gb:AF077959.1 gb:AF077961.1 gb:AF077962.1 gb:AF077966.1 gb:AF077971.1 AF015593 ceroid-lipofuscinosis, neuronal 3 CLN3 1201 NM_000086 /// NM_001042432 /// NM_001286104 /// NM_001286105 /// NM_001286109 /// NM_001286110 0000046 // autophagic vacuole fusion // inferred from sequence or structural similarity /// 0001508 // action potential // inferred from sequence or structural similarity /// 0001575 // globoside metabolic process // inferred from mutant phenotype /// 0006457 // protein folding // traceable author statement /// 0006520 // cellular amino acid metabolic process // inferred from sequence or structural similarity /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006678 // glucosylceramide metabolic process // inferred from mutant phenotype /// 0006681 // galactosylceramide metabolic process // inferred from mutant phenotype /// 0006684 // sphingomyelin metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007034 // vacuolar transport // not recorded /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0015809 // arginine transport // inferred from direct assay /// 0016236 // macroautophagy // non-traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from sequence or structural similarity /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030163 // protein catabolic process // non-traceable author statement /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035752 // lysosomal lumen pH elevation // inferred from direct assay /// 0042133 // neurotransmitter metabolic process // inferred from sequence or structural similarity /// 0042987 // amyloid precursor protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 209276_s_at AF162769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF162769.1 /DEF=Homo sapiens thioltransferase mRNA, complete cds. /FEA=mRNA /PROD=thioltransferase /DB_XREF=gi:5442445 /UG=Hs.28988 glutaredoxin (thioltransferase) /FL=gb:BC005304.1 gb:AF162769.1 gb:D21238.1 AF162769 glutaredoxin (thioltransferase) GLRX 2745 NM_001118890 /// NM_001243658 /// NM_001243659 /// NM_002064 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015038 // glutathione disulfide oxidoreductase activity // traceable author statement /// 0047485 // protein N-terminus binding // inferred from physical interaction 209277_at AL574096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574096 /FEA=EST /DB_XREF=gi:12933969 /DB_XREF=est:AL574096 /CLONE=CS0DI040YI17 (3 prime) /UG=Hs.295944 tissue factor pathway inhibitor 2 /FL=gb:BC005330.1 gb:L27624.1 gb:D29992.1 gb:NM_006528.1 AL574096 tissue factor pathway inhibitor 2 TFPI2 7980 NM_001271003 /// NM_001271004 /// NM_006528 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 209278_s_at L27624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L27624.1 /DEF=Homo sapiens tissue factor pathway inhibitor-2 mRNA, complete cds. /FEA=mRNA /PROD=tissue factor pathway inhibitor-2 /DB_XREF=gi:441149 /UG=Hs.295944 tissue factor pathway inhibitor 2 /FL=gb:BC005330.1 gb:L27624.1 gb:D29992.1 gb:NM_006528.1 L27624 tissue factor pathway inhibitor 2 TFPI2 7980 NM_001271003 /// NM_001271004 /// NM_006528 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 209279_s_at BC000245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000245.1 /DEF=Homo sapiens, NAD(P) dependent steroid dehydrogenase-like; H105e3, clone MGC:848, mRNA, complete cds. /FEA=mRNA /PROD=NAD(P) dependent steroid dehydrogenase-like;H105e3 /DB_XREF=gi:12652968 /UG=Hs.57698 NAD(P) dependent steroid dehydrogenase-like; H105e3 /FL=gb:BC000245.1 gb:U47105.2 gb:NM_015922.1 BC000245 NAD(P) dependent steroid dehydrogenase-like NSDHL 50814 NM_001129765 /// NM_015922 /// XM_006724824 0001942 // hair follicle development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047012 // sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 209280_at U58856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58856.1 /DEF=Human chromosome 17 unknown product mRNA, complete cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:2209262 /UG=Hs.7835 endocytic receptor (macrophage mannose receptor family) /FL=gb:U58856.1 gb:AB014609.1 gb:AF134838.1 gb:NM_006039.1 gb:AF107292.1 U58856 mannose receptor, C type 2 MRC2 9902 NM_006039 0001649 // osteoblast differentiation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from direct assay 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation 209281_s_at M95541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M95541.1 /DEF=Homo sapiens adenosine triphosphatase mRNA, complete cds. /FEA=mRNA /PROD=adenosine triphosphatase /DB_XREF=gi:184269 /UG=Hs.78546 ATPase, Ca++ transporting, plasma membrane 1 /FL=gb:M95541.1 gb:NM_001682.1 gb:J04027.1 M95541 ATPase, Ca++ transporting, plasma membrane 1 ATP2B1 490 NM_001001323 /// NM_001682 /// XM_005268919 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209282_at AF309082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF309082.1 /DEF=Homo sapiens protein kinase D2 mRNA, complete cds. /FEA=mRNA /PROD=protein kinase D2 /DB_XREF=gi:12659006 /UG=Hs.91146 protein kinase D2 /FL=gb:AF309082.1 gb:AF151021.1 gb:NM_016457.1 AF309082 protein kinase D2 PRKD2 25865 NM_001079880 /// NM_001079881 /// NM_001079882 /// NM_016457 /// XM_005258716 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from genetic interaction /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0032793 // positive regulation of CREB transcription factor activity // inferred from genetic interaction /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from genetic interaction /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from genetic interaction /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from genetic interaction /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0061154 // endothelial tube morphogenesis // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1901727 // positive regulation of histone deacetylase activity // inferred from genetic interaction /// 1902533 // positive regulation of intracellular signal transduction // inferred from mutant phenotype /// 2000573 // positive regulation of DNA biosynthetic process // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209283_at AF007162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF007162.1 /DEF=Homo sapiens unknown mRNA, complete cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3192942 /UG=Hs.1940 crystallin, alpha B /FL=gb:AF007162.1 gb:NM_001885.1 AF007162 crystallin, alpha B CRYAB 1410 NM_001289807 /// NM_001289808 /// NM_001885 0001666 // response to hypoxia // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0031109 // microtubule polymerization or depolymerization // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032387 // negative regulation of intracellular transport // inferred from direct assay /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from electronic annotation /// 0060561 // apoptotic process involved in morphogenesis // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from mutant phenotype /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0032432 // actin filament bundle // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from physical interaction 209284_s_at AI922509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922509 /FEA=EST /DB_XREF=gi:5658473 /DB_XREF=est:wh13g11.x1 /CLONE=IMAGE:2380676 /UG=Hs.23440 KIAA1105 protein /FL=gb:AF180425.2 AI922509 family with sequence similarity 208, member A FAM208A 23272 NM_001112736 /// NM_015224 /// XM_005264999 /// XM_006713077 /// XM_006713078 0044822 // poly(A) RNA binding // inferred from direct assay 209285_s_at N38985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N38985 /FEA=EST /DB_XREF=gi:1162192 /DB_XREF=est:yv21f02.s1 /CLONE=IMAGE:243387 /UG=Hs.23440 KIAA1105 protein /FL=gb:AF180425.2 N38985 family with sequence similarity 208, member A FAM208A 23272 NM_001112736 /// NM_015224 /// XM_005264999 /// XM_006713077 /// XM_006713078 0044822 // poly(A) RNA binding // inferred from direct assay 209286_at AI754416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI754416 /FEA=EST /DB_XREF=gi:5132680 /DB_XREF=est:cr25a08.x1 /CLONE=HBMSC_cr25a08 /UG=Hs.260024 Cdc42 effector protein 3 /FL=gb:AF094521.1 gb:AF104857.1 gb:NM_006449.1 gb:AF164118.1 gb:AL136842.1 AI754416 CDC42 effector protein (Rho GTPase binding) 3 CDC42EP3 10602 NM_001270436 /// NM_001270437 /// NM_001270438 /// NM_006449 0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005519 // cytoskeletal regulatory protein binding // traceable author statement 209287_s_at AF104857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF104857.1 /DEF=Homo sapiens Cdc42 effector protein 3 mRNA, complete cds. /FEA=mRNA /PROD=Cdc42 effector protein 3 /DB_XREF=gi:4324453 /UG=Hs.260024 Cdc42 effector protein 3 /FL=gb:AF094521.1 gb:AF104857.1 gb:NM_006449.1 gb:AF164118.1 gb:AL136842.1 AF104857 CDC42 effector protein (Rho GTPase binding) 3 CDC42EP3 10602 NM_001270436 /// NM_001270437 /// NM_001270438 /// NM_006449 0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005519 // cytoskeletal regulatory protein binding // traceable author statement 209288_s_at AL136842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136842.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A0530 (from clone DKFZp434A0530); complete cds. /FEA=mRNA /GEN=DKFZp434A0530 /PROD=hypothetical protein /DB_XREF=gi:6807668 /UG=Hs.260024 Cdc42 effector protein 3 /FL=gb:AF094521.1 gb:AF104857.1 gb:NM_006449.1 gb:AF164118.1 gb:AL136842.1 AL136842 CDC42 effector protein (Rho GTPase binding) 3 CDC42EP3 10602 NM_001270436 /// NM_001270437 /// NM_001270438 /// NM_006449 0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005519 // cytoskeletal regulatory protein binding // traceable author statement 209289_at AI700518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI700518 /FEA=EST /DB_XREF=gi:4988418 /DB_XREF=est:we37d09.x1 /CLONE=IMAGE:2343281 /UG=Hs.33287 nuclear factor IB /FL=gb:BC001283.1 gb:U85193.1 gb:NM_005596.1 AI700518 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 209290_s_at BC001283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001283.1 /DEF=Homo sapiens, Similar to nuclear factor IB, clone MGC:5146, mRNA, complete cds. /FEA=mRNA /PROD=Similar to nuclear factor IB /DB_XREF=gi:12654878 /UG=Hs.33287 nuclear factor IB /FL=gb:BC001283.1 gb:U85193.1 gb:NM_005596.1 BC001283 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 209291_at AW157094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157094 /FEA=EST /DB_XREF=gi:6228495 /DB_XREF=est:au91g11.x1 /CLONE=IMAGE:2783684 /UG=Hs.34853 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein /FL=gb:NM_001546.1 gb:U16153.1 gb:U28368.1 AW157094 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein ID4 3400 NM_001546 /// XM_005249076 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209292_at AL022726 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022726 /DEF=Human DNA sequence from clone 625H18 on chromosome 6p22.2-23. Contains the gene for ID4 Helix-loop-helix DNA binding protein and part of an alternatively spliced novel gene. Contains ESTs, STSs, GSSs and putative CpG islands /FEA=mRNA /DB_XREF=gi:3676217 /UG=Hs.34853 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein /FL=gb:NM_001546.1 gb:U16153.1 gb:U28368.1 AL022726 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein ID4 3400 NM_001546 /// XM_005249076 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209293_x_at U16153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16153.1 /DEF=Human Id-4H protein mRNA, complete cds. /FEA=mRNA /PROD=Id-4H protein /DB_XREF=gi:625095 /UG=Hs.34853 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein /FL=gb:NM_001546.1 gb:U16153.1 gb:U28368.1 U16153 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein ID4 3400 NM_001546 /// XM_005249076 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209294_x_at BC001281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001281.1 /DEF=Homo sapiens, tumor necrosis factor receptor superfamily, member 10b, clone MGC:5144, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor receptor superfamily,member 10b /DB_XREF=gi:12654874 /UG=Hs.51233 tumor necrosis factor receptor superfamily, member 10b /FL=gb:BC001281.1 gb:AF018658.1 gb:AF016849.1 gb:AF016266.1 BC001281 tumor necrosis factor receptor superfamily, member 10b TNFRSF10B 8795 NM_003842 /// NM_147187 /// NR_027140 /// XM_006716409 0006915 // apoptotic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045569 // TRAIL binding // non-traceable author statement 209295_at AF016266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF016266.1 /DEF=Homo sapiens TRAIL receptor 2 mRNA, complete cds. /FEA=mRNA /PROD=TRAIL receptor 2 /DB_XREF=gi:2529562 /UG=Hs.51233 tumor necrosis factor receptor superfamily, member 10b /FL=gb:BC001281.1 gb:AF018658.1 gb:AF016849.1 gb:AF016266.1 AF016266 tumor necrosis factor receptor superfamily, member 10b TNFRSF10B 8795 NM_003842 /// NM_147187 /// NR_027140 /// XM_006716409 0006915 // apoptotic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045569 // TRAIL binding // non-traceable author statement 209296_at AF136972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF136972.1 /DEF=Homo sapiens protein phosphatase 2C-like protein mRNA, complete cds. /FEA=mRNA /PROD=protein phosphatase 2C-like protein /DB_XREF=gi:12239323 /UG=Hs.5687 protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform /FL=gb:AF136972.1 gb:AF294792.1 AF136972 protein phosphatase, Mg2+/Mn2+ dependent, 1B PPM1B 5495 NM_001033556 /// NM_001033557 /// NM_002706 /// NM_177968 /// NM_177969 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209297_at AF114488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114488.1 /DEF=Homo sapiens intersectin short isoform (ITSN) mRNA, complete cds. /FEA=mRNA /GEN=ITSN /PROD=intersectin short isoform /DB_XREF=gi:4808824 /UG=Hs.66392 intersectin 1 (SH3 domain protein) /FL=gb:AF064243.1 gb:AF114488.1 AF114488 intersectin 1 (SH3 domain protein) ITSN1 6453 NM_001001132 /// NM_003024 /// XM_005261026 /// XM_005261027 /// XM_005261031 /// XR_244289 0006897 // endocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 209298_s_at AF114488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114488.1 /DEF=Homo sapiens intersectin short isoform (ITSN) mRNA, complete cds. /FEA=mRNA /GEN=ITSN /PROD=intersectin short isoform /DB_XREF=gi:4808824 /UG=Hs.66392 intersectin 1 (SH3 domain protein) /FL=gb:AF064243.1 gb:AF114488.1 AF114488 intersectin 1 (SH3 domain protein) ITSN1 6453 NM_001001132 /// NM_003024 /// XM_005261026 /// XM_005261027 /// XM_005261031 /// XR_244289 0006897 // endocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 209299_x_at BC000022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000022.1 /DEF=Homo sapiens, Similar to peptidylprolyl isomerase (cyclophilin)-like 2, clone MGC:787, mRNA, complete cds. /FEA=mRNA /PROD=Similar to peptidylprolyl isomerase(cyclophilin)-like 2 /DB_XREF=gi:13366578 /UG=Hs.93523 peptidylprolyl isomerase (cyclophilin)-like 2 /FL=gb:BC000022.1 BC000022 peptidylprolyl isomerase (cyclophilin)-like 2 PPIL2 23759 NM_014337 /// NM_148175 /// NM_148176 /// XM_005261447 /// XM_005261448 /// XM_006724197 /// XM_006724198 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 209300_s_at BC002888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002888.1 /DEF=Homo sapiens, Similar to DKFZP566B183 protein, clone MGC:10356, mRNA, complete cds. /FEA=mRNA /PROD=Similar to DKFZP566B183 protein /DB_XREF=gi:12804070 /UG=Hs.12305 DKFZP566B183 protein /FL=gb:BC002888.1 BC002888 NECAP endocytosis associated 1 NECAP1 25977 NM_015509 /// NR_024260 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030125 // clathrin vesicle coat // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209301_at M36532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36532.1 /DEF=Human carbonic anhydrase II mRNA, complete cds. /FEA=mRNA /GEN=CA2 /DB_XREF=gi:179794 /UG=Hs.155097 carbonic anhydrase II /FL=gb:J03037.1 gb:M36532.1 gb:NM_000067.1 M36532 carbonic anhydrase II CA2 760 NM_000067 /// NM_001293675 0001822 // kidney development // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0046903 // secretion // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from sequence or structural similarity /// 2001150 // positive regulation of dipeptide transmembrane transport // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209302_at U37689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U37689.1 /DEF=Human RNA polymerase II subunit (hsRPB8) mRNA, complete cds. /FEA=mRNA /GEN=hsRPB8 /PROD=RNA polymerase II subunit /DB_XREF=gi:1017822 /UG=Hs.3128 polymerase (RNA) II (DNA directed) polypeptide H /FL=gb:U37689.1 gb:BC000739.1 U37689 polymerase (RNA) II (DNA directed) polypeptide H POLR2H 5437 NM_001278698 /// NM_001278699 /// NM_001278700 /// NM_001278714 /// NM_001278715 /// NM_006232 /// XM_005247541 /// XM_006713666 /// XM_006713667 /// XM_006713668 /// XM_006713669 /// XM_006713670 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005730 // nucleolus // inferred from electronic annotation /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement 209303_at BC005270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005270.1 /DEF=Homo sapiens, NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD) (NADH-coenzyme Q reductase), clone MGC:12313, mRNA, complete cds. /FEA=mRNA /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 4(18kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:13528959 /UG=Hs.10758 NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD) (NADH-coenzyme Q reductase) /FL=gb:BC005270.1 gb:AF020351.1 gb:NM_002495.1 BC005270 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) NDUFS4 4724 NM_002495 /// XM_005248525 0001932 // regulation of protein phosphorylation // inferred from mutant phenotype /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0045271 // respiratory chain complex I // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation 209304_x_at AF087853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF087853.1 /DEF=Homo sapiens growth arrest and DNA damage inducible protein beta (GADD45B) mRNA, complete cds. /FEA=mRNA /GEN=GADD45B /PROD=growth arrest and DNA damage inducible proteinbeta /DB_XREF=gi:12061050 /UG=Hs.110571 growth arrest and DNA-damage-inducible, beta /FL=gb:AF087853.1 gb:AF078077.1 AF087853 growth arrest and DNA-damage-inducible, beta GADD45B 4616 NM_015675 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209305_s_at AF078077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078077.1 /DEF=Homo sapiens growth arrest and DNA-damage-inducible protein GADD45beta mRNA, complete cds. /FEA=mRNA /PROD=growth arrest and DNA-damage-inducible proteinGADD45beta /DB_XREF=gi:3978391 /UG=Hs.110571 growth arrest and DNA-damage-inducible, beta /FL=gb:AF087853.1 gb:AF078077.1 AF078077 growth arrest and DNA-damage-inducible, beta GADD45B 4616 NM_015675 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209306_s_at AI139569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI139569 /FEA=EST /DB_XREF=gi:3645541 /DB_XREF=est:qc57a12.x1 /CLONE=IMAGE:1713694 /UG=Hs.153026 SWAP-70 protein /FL=gb:BC000616.1 gb:AF210818.1 AI139569 SWAP switching B-cell complex 70kDa subunit SWAP70 23075 NM_015055 /// XM_005252829 /// XM_005252830 0016444 // somatic cell DNA recombination // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 209307_at AB014540 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014540.1 /DEF=Homo sapiens mRNA for KIAA0640 protein, partial cds. /FEA=mRNA /GEN=KIAA0640 /PROD=KIAA0640 protein /DB_XREF=gi:3327093 /UG=Hs.153026 SWAP-70 protein /FL=gb:BC000616.1 gb:AF210818.1 AB014540 SWAP switching B-cell complex 70kDa subunit SWAP70 23075 NM_015055 /// XM_005252829 /// XM_005252830 0016444 // somatic cell DNA recombination // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 209308_s_at BC002461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002461.1 /DEF=Homo sapiens, BCL2adenovirus E1B 19kD-interacting protein 2, clone MGC:1529, mRNA, complete cds. /FEA=mRNA /PROD=BCL2adenovirus E1B 19kD-interacting protein 2 /DB_XREF=gi:12803290 /UG=Hs.155596 BCL2adenovirus E1B 19kD-interacting protein 2 /FL=gb:BC002461.1 BC002461 BCL2/adenovirus E1B 19kDa interacting protein 2 BNIP2 663 NM_004330 /// XM_005254607 0001824 // blastocyst development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from physical interaction /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051297 // centrosome organization // inferred from electronic annotation 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // not recorded 209309_at D90427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D90427.1 /DEF=Human mRNA for zinc-alpha2-glycoprotein, complete cds. /FEA=mRNA /PROD=zinc-alpha2-glycoprotein precursor /DB_XREF=gi:220150 /UG=Hs.71 alpha-2-glycoprotein 1, zinc /FL=gb:D90427.1 gb:M76707.1 gb:NM_001185.1 D90427 alpha-2-glycoprotein 1, zinc-binding AZGP1 563 NM_001185 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0071806 // protein transmembrane transport // non-traceable author statement /// 0090501 // RNA phosphodiester bond hydrolysis // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // not recorded /// 0004540 // ribonuclease activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008320 // protein transmembrane transporter activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 209310_s_at U25804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U25804.1 /DEF=Human Ich-2 cysteine protease mRNA, complete cds. /FEA=mRNA /PROD=Ich-2 /DB_XREF=gi:886049 /UG=Hs.74122 caspase 4, apoptosis-related cysteine protease /FL=gb:U28976.1 gb:U28977.1 gb:U28978.1 gb:NM_001225.1 gb:U25804.1 gb:U28014.1 U25804 caspase 4, apoptosis-related cysteine peptidase CASP4 837 NM_001225 /// NM_033306 /// NM_033307 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0097194 // execution phase of apoptosis // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0072557 // IPAF inflammasome complex // not recorded /// 0072559 // NLRP3 inflammasome complex // not recorded /// 0097169 // AIM2 inflammasome complex // not recorded 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209311_at D87461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87461.1 /DEF=Human mRNA for KIAA0271 gene, complete cds. /FEA=mRNA /GEN=KIAA0271 /DB_XREF=gi:1944417 /UG=Hs.75244 BCL2-like 2 /FL=gb:U59747.1 gb:D87461.1 gb:NM_004050.1 D87461 BCL2-like 2 BCL2L2 599 NM_001199839 /// NM_004050 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded /// 0051400 // BH domain binding // inferred from electronic annotation 209312_x_at U65585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U65585.1 /DEF=Homo sapiens MHC class II antigen (HLA-DRB1) mRNA, HLA-DRB1*PBL allele, complete cds. /FEA=mRNA /GEN=HLA-DRB1 /PROD=MHC class II antigen /DB_XREF=gi:5478215 /UG=Hs.180255 major histocompatibility complex, class II, DR beta 1 /FL=gb:M33600.1 gb:NM_002124.1 gb:M28583.1 gb:U65585.1 U65585 major histocompatibility complex, class II, DQ beta 1 /// major histocompatibility complex, class II, DR beta 1 /// major histocompatibility complex, class II, DR beta 4 /// major histocompatibility complex, class II, DR beta 5 /// HLA class II histocompatibility antigen, DRB1-10 beta chain-like /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// HLA-DRB1 /// HLA-DRB4 /// HLA-DRB5 /// LOC100996809 /// LOC101060835 3119 /// 3123 /// 3126 /// 3127 /// 100996809 /// 101060835 NM_001243961 /// NM_001243962 /// NM_001243965 /// NM_002123 /// NM_002124 /// NM_002125 /// NM_021983 /// XM_003960955 /// XM_005276082 /// XM_006710174 /// XM_006710243 /// XM_006725752 /// XM_006725860 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 /// XR_430944 /// XR_430980 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0042605 // peptide antigen binding // inferred from direct assay 209313_at AB044661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044661.1 /DEF=Homo sapiens XAB1 mRNA for XPA binding protein 1, complete cds. /FEA=mRNA /GEN=XAB1 /PROD=XPA binding protein 1 /DB_XREF=gi:11094140 /UG=Hs.18259 XPA binding protein 1; putative ATP(GTP)-binding protein /FL=gb:AB044661.1 AB044661 GPN-loop GTPase 1 GPN1 11321 NM_001145047 /// NM_001145048 /// NM_001145049 /// NM_007266 /// NR_026735 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209314_s_at AK024258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024258.1 /DEF=Homo sapiens cDNA FLJ14196 fis, clone NT2RP3002330, highly similar to Homo sapiens eRFS mRNA. /FEA=mRNA /DB_XREF=gi:10436590 /UG=Hs.221040 HBS1 (S. cerevisiae)-like /FL=gb:BC001465.1 gb:U87791.1 gb:NM_006620.1 AK024258 HBS1-like translational GTPase HBS1L 10767 NM_001145158 /// NM_001145207 /// NM_006620 /// XM_006715320 /// XR_245499 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 209315_at AW297143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW297143 /FEA=EST /DB_XREF=gi:6703779 /DB_XREF=est:UI-H-BI2-aie-h-03-0-UI.s1 /CLONE=IMAGE:2729308 /UG=Hs.221040 HBS1 (S. cerevisiae)-like /FL=gb:BC001465.1 gb:U87791.1 gb:NM_006620.1 AW297143 HBS1-like translational GTPase HBS1L 10767 NM_001145158 /// NM_001145207 /// NM_006620 /// XM_006715320 /// XR_245499 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 209316_s_at BC001465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001465.1 /DEF=Homo sapiens, HBS1 (S. cerevisiae)-like, clone MGC:1869, mRNA, complete cds. /FEA=mRNA /PROD=HBS1 (S. cerevisiae)-like /DB_XREF=gi:12655212 /UG=Hs.221040 HBS1 (S. cerevisiae)-like /FL=gb:BC001465.1 gb:U87791.1 gb:NM_006620.1 BC001465 HBS1-like translational GTPase HBS1L 10767 NM_001145158 /// NM_001145207 /// NM_006620 /// XM_006715320 /// XR_245499 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 209317_at AF008442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF008442.1 /DEF=Homo sapiens RNA polymerase I subunit hRPA39 mRNA, complete cds. /FEA=mRNA /PROD=RNA polymerase I subunit hRPA39 /DB_XREF=gi:2266928 /UG=Hs.5409 RNA polymerase I subunit /FL=gb:AF008442.1 AF008442 polymerase (RNA) I polypeptide C, 30kDa POLR1C 9533 NM_004875 /// NM_203290 /// XM_005249491 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // traceable author statement /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 209318_x_at BG547855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG547855 /FEA=EST /DB_XREF=gi:13546520 /DB_XREF=est:602576153F1 /CLONE=IMAGE:4704108 /UG=Hs.75825 pleiomorphic adenoma gene-like 1 /FL=gb:U72621.3 BG547855 pleiomorphic adenoma gene-like 1 PLAGL1 5325 NM_001080951 /// NM_001080952 /// NM_001080953 /// NM_001080954 /// NM_001080955 /// NM_001080956 /// NM_001289037 /// NM_001289038 /// NM_001289039 /// NM_001289040 /// NM_001289041 /// NM_001289042 /// NM_001289043 /// NM_001289044 /// NM_001289045 /// NM_001289046 /// NM_001289047 /// NM_001289048 /// NM_001289049 /// NM_002656 /// NM_006718 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209320_at AF033861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033861.1 /DEF=Homo sapiens type III adenylyl cyclase (AC-III) mRNA, complete cds. /FEA=mRNA /GEN=AC-III /PROD=type III adenylyl cyclase /DB_XREF=gi:4104225 /UG=Hs.8402 adenylate cyclase 3 /FL=gb:NM_004036.2 gb:AF033861.1 AF033861 adenylate cyclase 3 ADCY3 109 NM_004036 /// XM_005264102 /// XM_005264104 /// XM_005264105 /// XM_006711925 /// XM_006711926 /// XM_006711927 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209321_s_at AF033861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033861.1 /DEF=Homo sapiens type III adenylyl cyclase (AC-III) mRNA, complete cds. /FEA=mRNA /GEN=AC-III /PROD=type III adenylyl cyclase /DB_XREF=gi:4104225 /UG=Hs.8402 adenylate cyclase 3 /FL=gb:NM_004036.2 gb:AF033861.1 AF033861 adenylate cyclase 3 ADCY3 109 NM_004036 /// XM_005264102 /// XM_005264104 /// XM_005264105 /// XM_006711925 /// XM_006711926 /// XM_006711927 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209322_s_at AF227968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF227968.1 /DEF=Homo sapiens SH2-B beta signaling protein (SH2B) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=SH2B /PROD=SH2-B beta signaling protein /DB_XREF=gi:8163910 /UG=Hs.15744 SH2-B homolog /FL=gb:AF227968.1 AF227968 SH2B adaptor protein 1 SH2B1 25970 NM_001145795 /// NM_001145796 /// NM_001145797 /// NM_001145812 /// NM_015503 /// XM_005255240 /// XM_006721031 /// XM_006721032 /// XM_006721033 /// XM_006721034 /// XM_006721035 /// XM_006721036 /// XM_006721037 0006928 // cellular component movement // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from electronic annotation /// 2000278 // regulation of DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 209323_at AF081567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081567.1 /DEF=Homo sapiens death associated protein 4 (DAP4) mRNA, complete cds. /FEA=mRNA /GEN=DAP4 /PROD=death associated protein 4 /DB_XREF=gi:9886758 /UG=Hs.177574 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) /FL=gb:AF007393.1 gb:NM_004705.1 gb:AF081567.1 AF081567 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) PRKRIR 5612 NM_004705 0006950 // response to stress // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 209324_s_at BF304996 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF304996 /FEA=EST /DB_XREF=gi:11251810 /DB_XREF=est:601888511F1 /CLONE=IMAGE:4122242 /UG=Hs.183601 regulator of G-protein signalling 16 /FL=gb:U70426.1 gb:U94829.1 gb:NM_002928.1 BF304996 regulator of G-protein signaling 16 RGS16 6004 NM_002928 0007601 // visual perception // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement 209325_s_at U94829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94829.1 /DEF=Human retinally abundant regulator of G-protein signaling hRGS-r (hRGS-r) mRNA, complete cds. /FEA=mRNA /GEN=hRGS-r /PROD=retinally abundant regulator of G-proteinsignaling hRGS-r /DB_XREF=gi:2605639 /UG=Hs.183601 regulator of G-protein signalling 16 /FL=gb:U70426.1 gb:U94829.1 gb:NM_002928.1 U94829 regulator of G-protein signaling 16 RGS16 6004 NM_002928 0007601 // visual perception // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement 209326_at D84454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D84454.1 /DEF=Human mRNA for UDP-galactose translocator, complete cds. /FEA=mRNA /PROD=UDP-galactose translocator /DB_XREF=gi:1526437 /UG=Hs.21899 solute carrier family 35 (UDP-galactose transporter), member 2 /FL=gb:D84454.1 D84454 solute carrier family 35 (UDP-galactose transporter), member A2 SLC35A2 7355 NM_001032289 /// NM_001042498 /// NM_001282647 /// NM_001282648 /// NM_001282649 /// NM_001282650 /// NM_001282651 /// NM_005660 0006012 // galactose metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015785 // UDP-galactose transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072334 // UDP-galactose transmembrane transport // inferred from electronic annotation /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005459 // UDP-galactose transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209327_s_at BC000587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000587.1 /DEF=Homo sapiens, clone MGC:2198, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2198) /DB_XREF=gi:12653618 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) /FL=gb:BC000587.1 BC000587 NOP16 nucleolar protein NOP16 51491 NM_001256539 /// NM_001256540 /// NM_001291305 /// NM_001291306 /// NM_001291307 /// NM_001291308 /// NM_016391 0001867 // complement activation, lectin pathway // inferred from electronic annotation /// 0001867 // complement activation, lectin pathway // inferred from mutant phenotype /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 209328_x_at AA243508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA243508 /FEA=EST /DB_XREF=gi:1874363 /DB_XREF=est:zs15h01.s1 /CLONE=IMAGE:685297 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) /FL=gb:BC000587.1 AA243508 HIG1 hypoxia inducible domain family, member 2A HIGD2A 192286 NM_138820 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 209329_x_at BC000587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000587.1 /DEF=Homo sapiens, clone MGC:2198, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2198) /DB_XREF=gi:12653618 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) /FL=gb:BC000587.1 BC000587 HIG1 hypoxia inducible domain family, member 2A HIGD2A 192286 NM_138820 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 209330_s_at D55674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D55674.1 /DEF=Human mRNA for heterogeneous nuclear ribonucleoprotein D (hnRNP D), complete cds, clone cDx9. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein D (hnRNPD) /DB_XREF=gi:870748 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:BC002401.1 gb:D55674.1 D55674 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209331_s_at AA723514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA723514 /FEA=EST /DB_XREF=gi:2741221 /DB_XREF=est:zg72g05.s1 /CLONE=IMAGE:398936 /UG=Hs.42712 MAX protein /FL=gb:BC003525.1 AA723514 MYC associated factor X MAX 4149 NM_001271068 /// NM_001271069 /// NM_002382 /// NM_145112 /// NM_145113 /// NM_145114 /// NM_145116 /// NM_197957 /// NR_073137 /// NR_073138 /// XR_429315 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 209332_s_at BC003525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003525.1 /DEF=Homo sapiens, Similar to Max, clone MGC:10775, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Max /DB_XREF=gi:13097617 /UG=Hs.42712 MAX protein /FL=gb:BC003525.1 BC003525 MYC associated factor X MAX 4149 NM_001271068 /// NM_001271069 /// NM_002382 /// NM_145112 /// NM_145113 /// NM_145114 /// NM_145116 /// NM_197957 /// NR_073137 /// NR_073138 /// XR_429315 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 209333_at AB018265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB018265.1 /DEF=Homo sapiens mRNA for KIAA0722 protein, complete cds. /FEA=mRNA /GEN=KIAA0722 /PROD=KIAA0722 protein /DB_XREF=gi:3882164 /UG=Hs.47061 unc-51 (C. elegans)-like kinase 1 /FL=gb:AF045458.1 gb:AB018265.1 gb:NM_003565.1 AB018265 unc-51 like autophagy activating kinase 1 ULK1 8408 NM_003565 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0010506 // regulation of autophagy // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0021933 // radial glia guided migration of cerebellar granule cell // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded /// 0051386 // regulation of neurotrophin TRK receptor signaling pathway // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from physical interaction 209334_s_at BC002383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002383.1 /DEF=Homo sapiens, proteasome (prosome, macropain) 26S subunit, non-ATPase, 9, clone MGC:8644, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 9 /DB_XREF=gi:12803158 /UG=Hs.5648 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 /FL=gb:BC002383.1 gb:BC004184.1 gb:BC004213.1 BC002383 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 PSMD9 5715 NM_001261400 /// NM_002813 /// NR_048555 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from sequence or structural similarity /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // non-traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from sequence or structural similarity 209335_at AI281593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI281593 /FEA=EST /DB_XREF=gi:3919826 /DB_XREF=est:qu47e10.x1 /CLONE=IMAGE:1967946 /UG=Hs.76152 decorin /FL=gb:BC005322.1 AI281593 decorin DCN 1634 NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 209336_at U56085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U56085.1 /DEF=Human periodic tryptophan protein 2 (PWP2) mRNA, complete cds. /FEA=mRNA /GEN=PWP2 /PROD=periodic tryptophan protein 2 /DB_XREF=gi:1737065 /UG=Hs.79380 PWP2 (periodic tryptophan protein, yeast) homolog /FL=gb:U53346.1 gb:U56085.1 gb:NM_005049.1 U56085 PWP2 periodic tryptophan protein homolog (yeast) PWP2 5822 NM_005049 0007165 // signal transduction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209337_at AF063020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF063020.1 /DEF=Homo sapiens lens epithelium-derived growth factor mRNA, complete cds. /FEA=mRNA /PROD=lens epithelium-derived growth factor /DB_XREF=gi:3283351 /UG=Hs.82110 PC4 and SFRS1 interacting protein 1 /FL=gb:NM_021144.1 gb:AF063020.1 AF063020 PC4 and SFRS1 interacting protein 1 PSIP1 11168 NM_001128217 /// NM_021144 /// NM_033222 /// XM_005251355 /// XM_005251356 /// XM_005251357 /// XM_005251358 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034399 // nuclear periphery // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from sequence or structural similarity 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097100 // supercoiled DNA binding // inferred from sequence or structural similarity 209338_at U03494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03494.1 /DEF=Human transcription factor LSF mRNA, complete cds. /FEA=mRNA /PROD=transcription factor LSF /DB_XREF=gi:476098 /UG=Hs.154970 transcription factor CP2 /FL=gb:BC003634.1 gb:U03494.1 U03494 transcription factor CP2 TFCP2 7024 NM_001173452 /// NM_001173453 /// NM_005653 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 209339_at U76248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U76248.1 /DEF=Human hSIAH2 mRNA, complete cds. /FEA=mRNA /PROD=hSIAH2 /DB_XREF=gi:2673967 /UG=Hs.20191 seven in absentia (Drosophila) homolog 2 /FL=gb:U76248.1 gb:NM_005067.1 U76248 siah E3 ubiquitin protein ligase 2 SIAH2 6478 NM_005067 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0044257 // cellular protein catabolic process // inferred from genetic interaction /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 2001141 // regulation of RNA biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031624 // ubiquitin conjugating enzyme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209340_at S73498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S73498.1 /DEF=Homo sapiens AgX-1 antigen mRNA, complete cds. /FEA=mRNA /PROD=AgX-1 antigen /DB_XREF=gi:688010 /UG=Hs.21293 UDP-N-acteylglucosamine pyrophosphorylase 1 /FL=gb:AB011004.1 gb:NM_003115.1 gb:S73498.1 S73498 UDP-N-acteylglucosamine pyrophosphorylase 1 UAP1 6675 NM_003115 /// XM_005245462 /// XM_005245465 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003977 // UDP-N-acetylglucosamine diphosphorylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 209341_s_at AU153366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153366 /FEA=EST /DB_XREF=gi:11014887 /DB_XREF=est:AU153366 /CLONE=NT2RP3002988 /UG=Hs.226573 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta /FL=gb:AF031416.1 gb:AF080158.1 AU153366 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta IKBKB 3551 NM_001190720 /// NM_001190721 /// NM_001190722 /// NM_001242778 /// NM_001556 /// NR_033818 /// NR_033819 /// NR_040009 /// XM_005273490 /// XM_005273491 /// XM_005273492 /// XM_005273493 /// XM_005273494 /// XM_005273495 /// XM_005273496 /// XM_005273498 /// XM_005273499 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042501 // serine phosphorylation of STAT protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from direct assay 209342_s_at AF080158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080158.1 /DEF=Homo sapiens IkB kinase-b (IKK-beta) mRNA, complete cds. /FEA=mRNA /GEN=IKK-beta /PROD=IkB kinase-b /DB_XREF=gi:4185274 /UG=Hs.226573 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta /FL=gb:AF031416.1 gb:AF080158.1 AF080158 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta IKBKB 3551 NM_001190720 /// NM_001190721 /// NM_001190722 /// NM_001242778 /// NM_001556 /// NR_033818 /// NR_033819 /// NR_040009 /// XM_005273490 /// XM_005273491 /// XM_005273492 /// XM_005273493 /// XM_005273494 /// XM_005273495 /// XM_005273496 /// XM_005273498 /// XM_005273499 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042501 // serine phosphorylation of STAT protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from direct assay 209343_at BC002449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002449.1 /DEF=Homo sapiens, Similar to CG10641 gene product, clone MGC:3052, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG10641 gene product /DB_XREF=gi:12803268 /UG=Hs.24391 hypothetical protein FLJ13612 /FL=gb:BC002449.1 BC002449 EF-hand domain family, member D1 EFHD1 80303 NM_001243252 /// NM_025202 0031175 // neuron projection development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209344_at BC002827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002827.1 /DEF=Homo sapiens, tropomyosin 4, clone MGC:3641, mRNA, complete cds. /FEA=mRNA /PROD=tropomyosin 4 /DB_XREF=gi:12803958 /UG=Hs.250641 tropomyosin 4 /FL=gb:BC002827.1 gb:NM_003290.1 BC002827 tropomyosin 4 TPM4 7171 NM_001145160 /// NM_003290 /// XM_005260042 /// XM_006722865 0001649 // osteoblast differentiation // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209345_s_at AL561930 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL561930 /FEA=EST /DB_XREF=gi:12909848 /DB_XREF=est:AL561930 /CLONE=CS0DB002YM13 (3 prime) /UG=Hs.25300 phosphatidylinositol 4-kinase type II /FL=gb:BC003167.1 AL561930 phosphatidylinositol 4-kinase type 2 alpha PI4K2A 55361 NM_018425 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0035838 // growing cell tip // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044231 // host cell presynaptic membrane // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035651 // AP-3 adaptor complex binding // inferred from direct assay 209346_s_at BC003167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003167.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ11105, clone MGC:4395, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ11105 /DB_XREF=gi:13111988 /UG=Hs.25300 phosphatidylinositol 4-kinase type II /FL=gb:BC003167.1 BC003167 phosphatidylinositol 4-kinase type 2 alpha PI4K2A 55361 NM_018425 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0035838 // growing cell tip // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044231 // host cell presynaptic membrane // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035651 // AP-3 adaptor complex binding // inferred from direct assay 209347_s_at BF508646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508646 /FEA=EST /DB_XREF=gi:11591944 /DB_XREF=est:UI-H-BI4-aop-b-03-0-UI.s1 /CLONE=IMAGE:3085397 /UG=Hs.30250 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog /FL=gb:AF055376.1 BF508646 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog MAF 4094 NM_001031804 /// NM_005360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209348_s_at AF055376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF055376.1 /DEF=Homo sapiens short form transcription factor C-MAF (c-maf) mRNA, complete cds. /FEA=mRNA /GEN=c-maf /PROD=short form transcription factor C-MAF /DB_XREF=gi:3335147 /UG=Hs.30250 v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog /FL=gb:AF055376.1 AF055376 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog MAF 4094 NM_001031804 /// NM_005360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209349_at U63139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63139.1 /DEF=Homo sapiens Rad50 (Rad50) mRNA, complete cds. /FEA=mRNA /GEN=Rad50 /PROD=Rad50 /DB_XREF=gi:1518805 /UG=Hs.41587 RAD50 (S. cerevisiae) homolog /FL=gb:U63139.1 U63139 RAD50 homolog (S. cerevisiae) RAD50 10111 NM_005732 /// NM_133482 0000019 // regulation of mitotic recombination // inferred from direct assay /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209350_s_at AL157493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL157493.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A0312 (from clone DKFZp434A0312); complete cds. /FEA=mRNA /GEN=DKFZp434A0312 /PROD=hypothetical protein /DB_XREF=gi:7018539 /UG=Hs.7301 G protein pathway suppressor 2 /FL=gb:AL157493.1 AL157493 G protein pathway suppressor 2 GPS2 2874 NM_004489 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000188 // inactivation of MAPK activity // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0046329 // negative regulation of JNK cascade // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209351_at BC002690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002690.1 /DEF=Homo sapiens, keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner), clone MGC:3944, mRNA, complete cds. /FEA=mRNA /PROD=keratin 14 (epidermolysis bullosa simplex,Dowling-Meara, Koebner) /DB_XREF=gi:12803708 /UG=Hs.117729 keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) /FL=gb:BC002690.1 gb:NM_000526.1 BC002690 keratin 14 KRT14 3861 NM_000526 0007568 // aging // inferred from direct assay /// 0008544 // epidermis development // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042633 // hair cycle // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030280 // structural constituent of epidermis // non-traceable author statement /// 1990254 // keratin filament binding // inferred from physical interaction 209352_s_at AB014600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014600.1 /DEF=Homo sapiens mRNA for KIAA0700 protein, partial cds. /FEA=mRNA /GEN=KIAA0700 /PROD=KIAA0700 protein /DB_XREF=gi:3327213 /UG=Hs.13999 KIAA0700 protein /FL=gb:BC001205.1 AB014600 SIN3 transcription regulator family member B SIN3B 23309 NM_015260 /// XM_005259832 /// XM_006722704 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030849 // autosome // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209353_s_at BC001205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001205.1 /DEF=Homo sapiens, Similar to KIAA0700 protein, clone MGC:3206, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0700 protein /DB_XREF=gi:12654726 /UG=Hs.13999 KIAA0700 protein /FL=gb:BC001205.1 BC001205 209354_at BC002794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002794.1 /DEF=Homo sapiens, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), clone MGC:3753, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor receptor superfamily,member 14 (herpesvirus entry mediator) /DB_XREF=gi:12803894 /UG=Hs.279899 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) /FL=gb:BC002794.1 gb:U70321.1 gb:U81232.1 gb:NM_003820.1 gb:AF153978.1 BC002794 tumor necrosis factor receptor superfamily, member 14 TNFRSF14 8764 NM_003820 /// XM_006711018 /// XM_006711019 /// XM_006711020 /// XM_006724946 /// XM_006724947 /// XM_006724948 /// XR_426638 /// XR_430632 0002741 // positive regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 2000406 // positive regulation of T cell migration // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 209355_s_at AB000889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000889.1 /DEF=Homo sapiens mRNA for phosphatidic acid phosphatase 2b, complete cds. /FEA=mRNA /PROD=phosphatidic acid phosphatase 2b /DB_XREF=gi:2467299 /UG=Hs.331371 phosphatidic acid phosphatase type 2B /FL=gb:U79294.1 gb:AB000889.1 gb:AF017786.1 AB000889 phosphatidic acid phosphatase type 2B PPAP2B 8613 NM_003713 /// NM_177414 0001568 // blood vessel development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008354 // germ cell migration // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044328 // canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0044329 // canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion // inferred from mutant phenotype /// 0044330 // canonical Wnt signaling pathway involved in positive regulation of wound healing // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from electronic annotation 209356_x_at AB030655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030655.1 /DEF=Homo sapiens mRNA for mutant p53 binding protein 1 (MBP1), complete cds. /FEA=mRNA /GEN=MBP1 /PROD=mutant p53 binding protein 1 (MBP1) /DB_XREF=gi:7328920 /UG=Hs.6059 EGF-containing fibulin-like extracellular matrix protein 2 /FL=gb:AF124486.1 gb:AB030655.1 AB030655 EGF containing fibulin-like extracellular matrix protein 2 EFEMP2 30008 NM_016938 /// NR_037718 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209357_at AF109161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109161.1 /DEF=Homo sapiens p35srj (MRG1) mRNA, complete cds. /FEA=mRNA /GEN=MRG1 /PROD=p35srj /DB_XREF=gi:4193945 /UG=Hs.82071 Cbpp300-interacting transactivator, with GluAsp-rich carboxy-terminal domain, 2 /FL=gb:BC004377.1 gb:AF109161.1 AF109161 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 CITED2 10370 NM_001168388 /// NM_001168389 /// NM_006079 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007530 // sex determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021602 // cranial nerve morphogenesis // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from mutant phenotype /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046697 // decidualization // inferred from electronic annotation /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060971 // embryonic heart tube left/right pattern formation // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from electronic annotation /// 0061308 // cardiac neural crest cell development involved in heart development // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900164 // nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0050693 // LBD domain binding // inferred from physical interaction 209358_at AF118094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118094.1 /DEF=Homo sapiens PRO2134 mRNA, complete cds. /FEA=mRNA /PROD=PRO2134 /DB_XREF=gi:6650833 /UG=Hs.83126 TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD /FL=gb:D63705.1 gb:NM_005643.1 gb:AF118094.1 AF118094 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa TAF11 6882 NM_001270488 /// NM_005643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 209359_x_at L34598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34598.1 /DEF=Homo sapiens (clone PEBP2aB) aml1 (acute myeloid leukemia 1) oncogene (AML1) mRNA, complete cds. /FEA=mRNA /GEN=AML1 /PROD=aml 1 (acute myeloid leukemia 1) oncogene /DB_XREF=gi:530134 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:L34598.1 gb:D43968.1 L34598 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 209360_s_at D43968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D43968.1 /DEF=Human AML1 mRNA for AML1b protein (alternatively spliced product), complete cds. /FEA=mRNA /GEN=AML1 /PROD=AML1b protein /DB_XREF=gi:966996 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:L34598.1 gb:D43968.1 D43968 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 209361_s_at BC004153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004153.1 /DEF=Homo sapiens, Similar to poly(rC)-binding protein 4, clone MGC:2386, mRNA, complete cds. /FEA=mRNA /PROD=Similar to poly(rC)-binding protein 4 /DB_XREF=gi:13278755 /UG=Hs.20930 poly(rC)-binding protein 4 /FL=gb:BC003008.1 gb:BC004153.1 BC004153 poly(rC) binding protein 4 PCBP4 57060 NM_001174100 /// NM_020418 /// NM_033008 /// NM_033009 /// NM_033010 /// XM_005265330 /// XM_005265331 /// XM_005265332 /// XM_006713266 /// XM_006713267 /// XM_006713268 /// XM_006713269 /// XM_006713270 /// XM_006713271 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 209362_at AI688580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688580 /FEA=EST /DB_XREF=gi:4899874 /DB_XREF=est:wd39h05.x1 /CLONE=IMAGE:2330553 /UG=Hs.286145 SRB7 (suppressor of RNA polymerase B, yeast) homolog /FL=gb:U46837.1 gb:U52960.1 gb:NM_004264.1 AI688580 uncharacterized LOC101928625 /// mediator complex subunit 21 LOC101928625 /// MED21 9412 /// 101928625 NM_001271811 /// NM_004264 /// NR_073463 /// NR_073464 /// XR_242927 /// XR_247794 /// XR_253033 0001824 // blastocyst development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 209363_s_at U46837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46837.1 /DEF=Human RNA polymerase II holoenzyme component SRB7 (SRB7) mRNA, complete cds. /FEA=mRNA /GEN=SRB7 /PROD=SRB7 /DB_XREF=gi:1197662 /UG=Hs.286145 SRB7 (suppressor of RNA polymerase B, yeast) homolog /FL=gb:U46837.1 gb:U52960.1 gb:NM_004264.1 U46837 uncharacterized LOC101928625 /// mediator complex subunit 21 LOC101928625 /// MED21 9412 /// 101928625 NM_001271811 /// NM_004264 /// NR_073463 /// NR_073464 /// XR_242927 /// XR_247794 /// XR_253033 0001824 // blastocyst development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 209364_at U66879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66879.1 /DEF=Human Bcl-2 binding component 6 (bbc6) mRNA, complete cds. /FEA=mRNA /GEN=bbc6 /PROD=Bcl-2 binding component 6 /DB_XREF=gi:1683636 /UG=Hs.76366 BCL2-antagonist of cell death /FL=gb:NM_004322.1 gb:BC001901.1 gb:U66879.1 gb:AF031523.1 U66879 BCL2-associated agonist of cell death BAD 572 NM_004322 /// NM_032989 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010918 // positive regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019050 // suppression by virus of host apoptotic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044342 // type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046031 // ADP metabolic process // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from sequence or structural similarity /// 0046902 // regulation of mitochondrial membrane permeability // inferred from mutant phenotype /// 0046931 // pore complex assembly // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060139 // positive regulation of apoptotic process by virus // inferred from electronic annotation /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071247 // cellular response to chromate // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071316 // cellular response to nicotine // inferred from direct assay /// 0071396 // cellular response to lipid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from electronic annotation /// 2000078 // positive regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from mutant phenotype /// 0008289 // lipid binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209365_s_at U65932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U65932.1 /DEF=Human extracellular matrix protein 1 (ECM1) mRNA, complete cds. /FEA=mRNA /GEN=ECM1 /PROD=extracellular matrix protein 1 /DB_XREF=gi:1488323 /UG=Hs.81071 extracellular matrix protein 1 /FL=gb:NM_004425.2 gb:U65932.1 gb:U68186.1 U65932 extracellular matrix protein 1 ECM1 1893 NM_001202858 /// NM_004425 /// NM_022664 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002828 // regulation of type 2 immune response // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 2000404 // regulation of T cell migration // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005134 // interleukin-2 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043236 // laminin binding // inferred from physical interaction 209366_x_at M22865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M22865.1 /DEF=Human cytochrome b5 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181226 /UG=Hs.83834 cytochrome b-5 /FL=gb:M22865.1 M22865 cytochrome b5 type A (microsomal) CYB5A 1528 NM_001190807 /// NM_001914 /// NM_148923 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209367_at AB002559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002559.1 /DEF=Homo sapiens mRNA for hunc18b2, complete cds. /FEA=mRNA /PROD=hunc18b2 /DB_XREF=gi:1944129 /UG=Hs.90535 syntaxin binding protein 2 /FL=gb:BC002869.1 gb:U63533.1 gb:AB002559.1 gb:NM_006949.1 AB002559 syntaxin binding protein 2 STXBP2 6813 NM_001127396 /// NM_001272034 /// NM_006949 /// NR_073560 /// XM_006722851 0001909 // leukocyte mediated cytotoxicity // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043312 // neutrophil degranulation // inferred from expression pattern 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0044194 // cytolytic granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070820 // tertiary granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0030348 // syntaxin-3 binding // inferred from physical interaction 209368_at AF233336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF233336.1 /DEF=Homo sapiens clone 129-13 soluble epoxide hydrolase (EPHX2) mRNA, complete cds. /FEA=mRNA /GEN=EPHX2 /PROD=soluble epoxide hydrolase /DB_XREF=gi:10197683 /UG=Hs.113 epoxide hydrolase 2, cytoplasmic /FL=gb:AF233334.1 gb:AF233335.1 gb:AF233336.1 gb:L05779.1 gb:NM_001979.1 AF233336 epoxide hydrolase 2, cytoplasmic EPHX2 2053 NM_001256482 /// NM_001256483 /// NM_001256484 /// NM_001979 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0006874 // cellular calcium ion homeostasis // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0017144 // drug metabolic process // non-traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019439 // aromatic compound catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0046272 // stilbene catabolic process // inferred from direct assay /// 0046839 // phospholipid dephosphorylation // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // non-traceable author statement /// 0090181 // regulation of cholesterol metabolic process // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004301 // epoxide hydrolase activity // inferred from direct assay /// 0004301 // epoxide hydrolase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0015643 // toxic substance binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0033885 // 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209369_at M63310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M63310.1 /DEF=Human 1,2-cyclic-inositol-phosphate phosphodiesterase (ANX3) mRNA, complete cds. /FEA=mRNA /GEN=ANX3 /PROD=1,2-cyclic-inositol-phosphate phosphodiesterase /DB_XREF=gi:178696 /UG=Hs.1378 annexin A3 /FL=gb:BC000871.1 gb:M63310.1 gb:M20560.1 gb:NM_005139.1 M63310 annexin A3 ANXA3 306 NM_005139 /// XM_005262973 0006909 // phagocytosis // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0019834 // phospholipase A2 inhibitor activity // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 209370_s_at BE502377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE502377 /FEA=EST /DB_XREF=gi:9704785 /DB_XREF=est:hy22g03.x1 /CLONE=IMAGE:3198100 /UG=Hs.167679 SH3-domain binding protein 2 /FL=gb:AB000462.1 gb:AF000936.1 BE502377 SH3-domain binding protein 2 SH3BP2 6452 NM_001122681 /// NM_001145855 /// NM_001145856 /// NM_003023 /// XM_005247997 /// XM_005247998 /// XM_005247999 /// XM_005248000 /// XM_006713911 /// XM_006713912 /// XM_006713913 0007165 // signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 209371_s_at AB000462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000462.1 /DEF=Homo sapiens mRNA for SH3 binding protein, complete cds, clone:RES4-23A. /FEA=mRNA /PROD=SH3 binding protein /DB_XREF=gi:1843391 /UG=Hs.167679 SH3-domain binding protein 2 /FL=gb:AB000462.1 gb:AF000936.1 AB000462 SH3-domain binding protein 2 SH3BP2 6452 NM_001122681 /// NM_001145855 /// NM_001145856 /// NM_003023 /// XM_005247997 /// XM_005247998 /// XM_005247999 /// XM_005248000 /// XM_006713911 /// XM_006713912 /// XM_006713913 0007165 // signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 209372_x_at BF971587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF971587 /FEA=EST /DB_XREF=gi:12338802 /DB_XREF=est:602239834F1 /CLONE=IMAGE:4328385 /UG=Hs.179661 tubulin, beta polypeptide /FL=gb:BC001352.1 BF971587 tubulin, beta 2A class IIa /// tubulin, beta 2B class IIb TUBB2A /// TUBB2B 7280 /// 347733 NM_001069 /// NM_178012 0001764 // neuron migration // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 209373_at BC003179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003179.1 /DEF=Homo sapiens, clone MGC:4419, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4419) /DB_XREF=gi:13112010 /UG=Hs.185055 BENE protein /FL=gb:BC003179.1 gb:NM_005434.1 BC003179 mal, T-cell differentiation protein-like MALL 7851 NM_005434 0042632 // cholesterol homeostasis // non-traceable author statement 0000139 // Golgi membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209374_s_at BC001872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001872.1 /DEF=Homo sapiens, clone MGC:1228, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1228) /DB_XREF=gi:12804852 /UG=Hs.302063 immunoglobulin heavy constant mu /FL=gb:BC002963.1 gb:BC001872.1 BC001872 immunoglobulin heavy constant mu IGHM 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 209375_at D21089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D21089.1 /DEF=Human mRNA for XP-C repair complementing protein (p125), complete cds. /FEA=mRNA /GEN=XPCC /PROD=XP-C repair complementing protein (p125) /DB_XREF=gi:475156 /UG=Hs.320 xeroderma pigmentosum, complementation group C /FL=gb:D21089.1 gb:NM_004628.1 D21089 xeroderma pigmentosum, complementation group C XPC 7508 NM_001145769 /// NM_004628 /// NR_027299 /// XR_427290 0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 1901990 // regulation of mitotic cell cycle phase transition // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0000404 // heteroduplex DNA loop binding // traceable author statement /// 0000405 // bubble DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209376_x_at AW084759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW084759 /FEA=EST /DB_XREF=gi:6039911 /DB_XREF=est:xc57e01.x1 /CLONE=IMAGE:2588376 /UG=Hs.51957 splicing factor, arginineserine-rich 2, interacting protein /FL=gb:AF030234.1 AW084759 SR-related CTD-associated factor 11 SCAF11 9169 NM_004719 /// XM_005269230 /// XM_006719692 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209377_s_at AF274949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274949.1 /DEF=Homo sapiens PNAS-24 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-24 /DB_XREF=gi:12751062 /UG=Hs.77558 thyroid hormone receptor interactor 7 /FL=gb:AF274949.1 AF274949 high mobility group nucleosomal binding domain 3 HMGN3 9324 NM_001201362 /// NM_001201363 /// NM_004242 /// NM_138730 /// XM_005248768 /// XM_005248769 /// XM_006715604 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // non-traceable author statement 209378_s_at AI478879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478879 /FEA=EST /DB_XREF=gi:4372047 /DB_XREF=est:tm25a06.x1 /CLONE=IMAGE:2157586 /UG=Hs.81897 KIAA1128 protein /FL=gb:AF241785.1 AI478879 coiled-coil serine-rich protein 2 CCSER2 54462 NM_001284240 /// NM_001284241 /// NM_001284242 /// NM_001284243 /// NM_018999 /// XM_005269905 /// XM_005269906 /// XM_005269908 /// XM_006717894 /// XM_006717895 0001578 // microtubule bundle formation // inferred from electronic annotation 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation 209379_s_at AF241785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241785.1 /DEF=Homo sapiens NPD012 (NPD012) mRNA, complete cds. /FEA=mRNA /GEN=NPD012 /PROD=NPD012 /DB_XREF=gi:12005486 /UG=Hs.81897 KIAA1128 protein /FL=gb:AF241785.1 AF241785 coiled-coil serine-rich protein 2 CCSER2 54462 NM_001284240 /// NM_001284241 /// NM_001284242 /// NM_001284243 /// NM_018999 /// XM_005269905 /// XM_005269906 /// XM_005269908 /// XM_006717894 /// XM_006717895 0001578 // microtubule bundle formation // inferred from electronic annotation 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation 209380_s_at AF146074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF146074.1 /DEF=Homo sapiens ABC protein mRNA, complete cds. /FEA=mRNA /PROD=ABC protein /DB_XREF=gi:5006890 /UG=Hs.108660 ATP-binding cassette, sub-family C (CFTRMRP), member 5 /FL=gb:AF104942.1 gb:AB019002.1 gb:AF146074.1 gb:NM_005688.1 gb:U83661.2 AF146074 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 ABCC5 10057 NM_001023587 /// NM_005688 /// XM_005247058 /// XM_005247059 0005975 // carbohydrate metabolic process // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015711 // organic anion transport // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030213 // hyaluronan biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 209381_x_at BC004434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004434.1 /DEF=Homo sapiens, clone MGC:3975, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3975) /DB_XREF=gi:13325229 /UG=Hs.115232 splicing factor 3a, subunit 2, 66kD /FL=gb:BC004434.1 gb:NM_007165.1 BC004434 splicing factor 3a, subunit 2, 66kDa SF3A2 8175 NM_007165 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209382_at U93867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U93867.1 /DEF=Human RNA polymerase III subunit (RPC62) mRNA, complete cds. /FEA=mRNA /GEN=RPC62 /PROD=RNA polymerase III subunit /DB_XREF=gi:2228747 /UG=Hs.250745 polymerase (RNA) III (DNA directed) (62kD) /FL=gb:BC002586.1 gb:NM_006468.2 gb:U93867.1 U93867 polymerase (RNA) III (DNA directed) polypeptide C (62kD) POLR3C 10623 NM_006468 /// XM_005272927 /// XM_005272928 /// XM_005277333 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement 209383_at BC003637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003637.1 /DEF=Homo sapiens, Similar to DNA-damage-inducible transcript 3, clone MGC:4154, mRNA, complete cds. /FEA=mRNA /PROD=Similar to DNA-damage-inducible transcript 3 /DB_XREF=gi:13177717 /UG=Hs.279946 methionine-tRNA synthetase /FL=gb:BC003637.1 gb:NM_004083.1 BC003637 DNA-damage-inducible transcript 3 DDIT3 1649 NM_001195053 /// NM_001195054 /// NM_001195055 /// NM_001195056 /// NM_001195057 /// NM_004083 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001955 // blood vessel maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006983 // ER overload response // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042594 // response to starvation // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044324 // regulation of transcription involved in anterior/posterior axis specification // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000016 // negative regulation of determination of dorsal identity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209384_at AA176833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA176833 /FEA=EST /DB_XREF=gi:1757965 /DB_XREF=est:zp34f11.s1 /CLONE=IMAGE:611373 /UG=Hs.301959 proline synthetase co-transcribed (bacterial homolog) /FL=gb:AL136616.1 AA176833 proline synthetase co-transcribed homolog (bacterial) PROSC 11212 NM_007198 /// XM_005273395 1901605 // alpha-amino acid metabolic process // not recorded 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0030170 // pyridoxal phosphate binding // not recorded 209385_s_at AL136616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136616.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I2423 (from clone DKFZp564I2423); complete cds. /FEA=mRNA /GEN=DKFZp564I2423 /PROD=hypothetical protein /DB_XREF=gi:12052757 /UG=Hs.301959 proline synthetase co-transcribed (bacterial homolog) /FL=gb:AL136616.1 AL136616 proline synthetase co-transcribed homolog (bacterial) PROSC 11212 NM_007198 /// XM_005273395 1901605 // alpha-amino acid metabolic process // not recorded 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0030170 // pyridoxal phosphate binding // not recorded 209386_at AI346835 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346835 /FEA=EST /DB_XREF=gi:4084041 /DB_XREF=est:qp58g11.x1 /CLONE=IMAGE:1927268 /UG=Hs.3337 transmembrane 4 superfamily member 1 /FL=gb:M90657.1 AI346835 transmembrane 4 L six family member 1 TM4SF1 4071 NM_014220 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 209387_s_at M90657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90657.1 /DEF=Human tumor antigen (L6) mRNA, complete cds. /FEA=mRNA /GEN=L6 /DB_XREF=gi:186803 /UG=Hs.3337 transmembrane 4 superfamily member 1 /FL=gb:M90657.1 M90657 transmembrane 4 L six family member 1 TM4SF1 4071 NM_014220 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 209388_at BC000927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000927.1 /DEF=Homo sapiens, Similar to poly (A) polymerase, clone MGC:5378, mRNA, complete cds. /FEA=mRNA /PROD=Similar to poly (A) polymerase /DB_XREF=gi:12654216 /UG=Hs.49007 poly(A) polymerase alpha /FL=gb:BC000927.1 BC000927 poly(A) polymerase alpha PAPOLA 10914 NM_001252006 /// NM_001252007 /// NM_001293627 /// NM_001293628 /// NM_001293632 /// NM_032632 /// XM_005267280 /// XM_005267281 /// XM_005267282 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043631 // RNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209389_x_at M15887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15887.1 /DEF=Human endozepine (putative ligand of benzodiazepine receptor) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181960 /UG=Hs.78888 diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) /FL=gb:M15887.1 M15887 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) DBI 1622 NM_001079862 /// NM_001079863 /// NM_001178017 /// NM_001178041 /// NM_001178042 /// NM_001178043 /// NM_001282633 /// NM_001282634 /// NM_001282635 /// NM_001282636 /// NM_020548 /// NR_104221 0001942 // hair follicle development // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030156 // benzodiazepine receptor binding // traceable author statement /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 209390_at AF013168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF013168.1 /DEF=Homo sapiens hamartin (TSC1) mRNA, complete cds. /FEA=mRNA /GEN=TSC1 /PROD=hamartin /DB_XREF=gi:2331280 /UG=Hs.79393 tuberous sclerosis 1 (hamartin) /FL=gb:AF013168.1 gb:NM_000368.1 AF013168 tuberous sclerosis 1 TSC1 7248 NM_000368 /// NM_001008567 /// NM_001162426 /// NM_001162427 /// XM_005272211 /// XM_006717271 /// XM_006717272 0001822 // kidney development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006407 // rRNA export from nucleus // inferred from mutant phenotype /// 0006417 // regulation of translation // inferred from direct assay /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0032868 // response to insulin // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from mutant phenotype /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // not recorded /// 0050808 // synapse organization // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051492 // regulation of stress fiber assembly // inferred from direct assay /// 0051726 // regulation of cell cycle // not recorded /// 0051893 // regulation of focal adhesion assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0033596 // TSC1-TSC2 complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 209391_at AF061729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061729.1 /DEF=Homo sapiens clone 014b03 My026 protein mRNA, complete cds. /FEA=mRNA /PROD=My026 protein /DB_XREF=gi:12001993 /UG=Hs.108973 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit /FL=gb:AF061729.1 gb:AB013361.1 gb:NM_003863.1 AF061729 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit DPM2 8818 NM_003863 /// NM_152690 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019348 // dolichol metabolic process // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from physical interaction /// 0035269 // protein O-linked mannosylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0033185 // dolichol-phosphate-mannose synthase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004582 // dolichyl-phosphate beta-D-mannosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 209392_at L35594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L35594.1 /DEF=Human autotaxin mRNA, complete cds. /FEA=mRNA /PROD=autotaxin /DB_XREF=gi:537905 /UG=Hs.174185 ectonucleotide pyrophosphatasephosphodiesterase 2 (autotaxin) /FL=gb:L35594.1 L35594 ectonucleotide pyrophosphatase/phosphodiesterase 2 ENPP2 5168 NM_001040092 /// NM_001130863 /// NM_006209 /// NR_045555 /// XM_006716584 /// XM_006716585 /// XM_006716586 /// XM_006716587 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from direct assay /// 0034638 // phosphatidylcholine catabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // traceable author statement /// 0004551 // nucleotide diphosphatase activity // traceable author statement /// 0004622 // lysophospholipase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008134 // transcription factor binding // traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // traceable author statement /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047391 // alkylglycerophosphoethanolamine phosphodiesterase activity // inferred from electronic annotation 209393_s_at AF047695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047695.1 /DEF=Homo sapiens cap-binding protein 4EHP mRNA, complete cds. /FEA=mRNA /PROD=cap-binding protein 4EHP /DB_XREF=gi:3172338 /UG=Hs.19122 eukaryotic translation initiation factor 4E-like 3 /FL=gb:BC005392.1 gb:AF047695.1 gb:AF068117.1 gb:AF038957.1 gb:NM_004846.1 AF047695 eukaryotic translation initiation factor 4E family member 2 EIF4E2 9470 NM_001276336 /// NM_001276337 /// NM_001282958 /// NM_004846 /// XM_005246975 /// XR_427124 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209394_at BC002508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002508.1 /DEF=Homo sapiens, acetylserotonin O-methyltransferase-like, clone MGC:2940, mRNA, complete cds. /FEA=mRNA /PROD=acetylserotonin O-methyltransferase-like /DB_XREF=gi:12803374 /UG=Hs.6315 acetylserotonin O-methyltransferase-like /FL=gb:BC002508.1 gb:NM_004192.1 BC002508 acetylserotonin O-methyltransferase-like ASMTL 8623 NM_001173473 /// NM_001173474 /// NM_004192 /// XM_005274434 /// XM_005274783 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 209395_at M80927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80927.1 /DEF=Human glycoprotein mRNA, complete cds. /FEA=mRNA /PROD=glycoprotein /DB_XREF=gi:348911 /UG=Hs.75184 chitinase 3-like 1 (cartilage glycoprotein-39) /FL=gb:M80927.1 gb:NM_001276.1 M80927 chitinase 3-like 1 (cartilage glycoprotein-39) CHI3L1 1116 NM_001276 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from expression pattern /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0051216 // cartilage development // non-traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from expression pattern /// 0070741 // response to interleukin-6 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072606 // interleukin-8 secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008061 // chitin binding // inferred from direct assay 209396_s_at M80927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80927.1 /DEF=Human glycoprotein mRNA, complete cds. /FEA=mRNA /PROD=glycoprotein /DB_XREF=gi:348911 /UG=Hs.75184 chitinase 3-like 1 (cartilage glycoprotein-39) /FL=gb:M80927.1 gb:NM_001276.1 M80927 chitinase 3-like 1 (cartilage glycoprotein-39) CHI3L1 1116 NM_001276 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from expression pattern /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0051216 // cartilage development // non-traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from expression pattern /// 0070741 // response to interleukin-6 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072606 // interleukin-8 secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008061 // chitin binding // inferred from direct assay 209397_at BC000147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000147.1 /DEF=Homo sapiens, Similar to malic enzyme 2, NAD(+)-dependent, mitochondrial, clone MGC:5187, mRNA, complete cds. /FEA=mRNA /PROD=Similar to malic enzyme 2, NAD(+)-dependent,mitochondrial /DB_XREF=gi:12652790 /UG=Hs.75342 malic enzyme 2, NAD(+)-dependent, mitochondrial /FL=gb:BC000147.1 BC000147 malic enzyme 2, NAD(+)-dependent, mitochondrial ME2 4200 NM_001168335 /// NM_002396 0006108 // malate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // inferred from electronic annotation /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 209398_at BC002649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002649.1 /DEF=Homo sapiens, H1 histone family, member 2, clone MGC:3992, mRNA, complete cds. /FEA=mRNA /PROD=H1 histone family, member 2 /DB_XREF=gi:12803628 /UG=Hs.7644 H1 histone family, member 2 /FL=gb:BC002649.1 gb:NM_005319.1 BC002649 histone cluster 1, H1c HIST1H1C 3006 NM_005319 0006334 // nucleosome assembly // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209399_at D87328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87328.1 /DEF=Homo sapiens mRNA for HCS, complete cds. /FEA=mRNA /PROD=HCS /DB_XREF=gi:1813423 /UG=Hs.79375 holocarboxylase synthetase (biotin-proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing) ligase) /FL=gb:D87328.1 D87328 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) HLCS 3141 NM_000411 /// NM_001242784 /// NM_001242785 /// XM_005260953 /// XM_005260954 /// XM_005260955 /// XM_005260956 /// XM_006723993 /// XM_006723994 /// XM_006723995 /// XM_006723996 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009305 // protein biotinylation // inferred from direct assay /// 0016570 // histone modification // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0070781 // response to biotin // inferred from direct assay /// 0071110 // histone biotinylation // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005652 // nuclear lamina // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004077 // biotin-[acetyl-CoA-carboxylase] ligase activity // inferred from electronic annotation /// 0004078 // biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity // inferred from electronic annotation /// 0004079 // biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity // inferred from electronic annotation /// 0004080 // biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0018271 // biotin-protein ligase activity // inferred from direct assay /// 0018271 // biotin-protein ligase activity // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 209400_at U55054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U55054.1 /DEF=Human K-Cl cotransporter (hKCC1) mRNA, complete cds. /FEA=mRNA /GEN=hKCC1 /PROD=K-Cl cotransporter /DB_XREF=gi:1399211 /UG=Hs.10094 solute carrier family 12 (potassiumchloride transporters), member 4 /FL=gb:U55054.1 gb:AF047338.1 gb:NM_005072.1 U55054 solute carrier family 12 (potassium/chloride transporter), member 4 SLC12A4 6560 NM_001145961 /// NM_001145962 /// NM_001145963 /// NM_001145964 /// NM_005072 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006884 // cell volume homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 209401_s_at AI817690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817690 /FEA=EST /DB_XREF=gi:5436769 /DB_XREF=est:wk25a09.x1 /CLONE=IMAGE:2413336 /UG=Hs.10094 solute carrier family 12 (potassiumchloride transporters), member 4 /FL=gb:U55054.1 gb:AF047338.1 gb:NM_005072.1 AI817690 solute carrier family 12 (potassium/chloride transporter), member 4 SLC12A4 6560 NM_001145961 /// NM_001145962 /// NM_001145963 /// NM_001145964 /// NM_005072 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006884 // cell volume homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 209402_s_at AF047338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047338.1 /DEF=Homo sapiens erythroid K:Cl cotransporter (KCC1) mRNA, complete cds. /FEA=mRNA /GEN=KCC1 /PROD=erythroid K:Cl cotransporter /DB_XREF=gi:2921846 /UG=Hs.10094 solute carrier family 12 (potassiumchloride transporters), member 4 /FL=gb:U55054.1 gb:AF047338.1 gb:NM_005072.1 AF047338 solute carrier family 12 (potassium/chloride transporter), member 4 SLC12A4 6560 NM_001145961 /// NM_001145962 /// NM_001145963 /// NM_001145964 /// NM_005072 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006884 // cell volume homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 209403_at AL136860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136860.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P2235 (from clone DKFZp434P2235); complete cds. /FEA=mRNA /GEN=DKFZp434P2235 /PROD=hypothetical protein /DB_XREF=gi:12053224 /UG=Hs.105891 Homo sapiens mRNA; cDNA DKFZp434P2235 (from clone DKFZp434P2235); complete cds /FL=gb:AL136860.1 AL136860 TBC1 domain family member-like /// TBC1 domain family member-like /// TBC1 domain family member 3F-like /// TBC1 domain family member-like /// TBC1 domain family member-like /// TBC1 domain family member-like /// TBC1 domain family, member 3 /// TBC1 domain family, member 3C /// TBC1 domain family, member 3F /// TBC1 domain family, member 3H LOC101060321 /// LOC101060351 /// LOC101060376 /// LOC101060389 /// LOC102723859 /// LOC102724862 /// TBC1D3 /// TBC1D3C /// TBC1D3F /// TBC1D3H 84218 /// 414060 /// 729873 /// 729877 /// 101060321 /// 101060351 /// 101060376 /// 101060389 /// 102723859 /// 102724862 NM_001001418 /// NM_001040282 /// NM_001123391 /// NM_001123392 /// NM_001291459 /// NM_001291462 /// NM_001291463 /// NM_001291464 /// NM_001291465 /// NM_001291466 /// NM_032258 /// XM_003960688 /// XM_003960690 /// XM_003960693 /// XM_003960695 /// XM_003960697 /// XM_005257635 /// XM_005257636 /// XM_005257981 /// XM_005276604 /// XM_005276605 /// XM_005276606 /// XM_005276607 /// XM_005276608 /// XM_005276609 /// XM_005276610 /// XM_006721904 /// XM_006721905 /// XM_006721906 /// XM_006721907 /// XM_006721908 /// XM_006722055 /// XM_006722056 /// XM_006722057 /// XM_006722058 /// XM_006722222 /// XM_006722223 /// XM_006722224 /// XM_006722225 /// XM_006722226 /// XM_006722227 /// XM_006722228 /// XM_006722235 /// XM_006722236 /// XM_006722237 /// XM_006722238 /// XM_006722239 /// XM_006722240 /// XM_006722241 /// XM_006722242 /// XM_006722243 /// XM_006722244 /// XM_006722245 /// XM_006722246 /// XM_006722247 /// XM_006722248 /// XM_006722249 /// XM_006722250 /// XM_006722251 /// XM_006722252 /// XM_006722253 /// XM_006722254 /// XM_006725340 /// XM_006725341 /// XM_006725367 /// XM_006725368 /// XM_006725369 /// XM_006725370 /// XM_006725371 /// XM_006725372 /// XM_006725373 /// XM_006725384 /// XM_006725385 /// XM_006725386 /// XM_006725387 /// XM_006725388 /// XM_006725389 /// XM_006725390 /// XM_006725391 /// XM_006725572 /// XM_006725573 /// XM_006725574 /// XM_006725575 /// XM_006725576 /// XM_006725577 /// XM_006725578 /// XM_006725579 /// XM_006726718 /// XM_006726719 /// XM_006726720 /// XM_006726721 /// XM_006726722 /// XM_006726723 /// XM_006726724 /// XM_006726731 /// XM_006726732 /// XM_006726733 /// XM_006726734 /// XM_006726735 /// XM_006726736 /// XM_006726737 /// XM_006726738 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 209404_s_at AF151867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151867.1 /DEF=Homo sapiens CGI-109 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-109 protein /DB_XREF=gi:4929686 /UG=Hs.278391 CGI-109 protein /FL=gb:AF151867.1 AF151867 transmembrane emp24 protein transport domain containing 7 /// TMED7-TICAM2 readthrough TMED7 /// TMED7-TICAM2 51014 /// 100302736 NM_001164468 /// NM_001164469 /// NM_181836 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035669 // TRAM-dependent toll-like receptor 4 signaling pathway // inferred from direct assay /// 0035669 // TRAM-dependent toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0071650 // negative regulation of chemokine (C-C motif) ligand 5 production // inferred from mutant phenotype /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // inferred from mutant phenotype /// 2000494 // positive regulation of interleukin-18-mediated signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // traceable author statement /// 0030127 // COPII vesicle coat // traceable author statement /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype 209405_s_at BC002934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002934.1 /DEF=Homo sapiens, Similar to predicted osteoblast protein, clone MGC:10447, mRNA, complete cds. /FEA=mRNA /PROD=Similar to predicted osteoblast protein /DB_XREF=gi:12804156 /UG=Hs.289108 2.19 gene /FL=gb:BC002934.1 BC002934 family with sequence similarity 3, member A FAM3A 60343 NM_001171132 /// NM_001171133 /// NM_001171134 /// NM_001282311 /// NM_001282312 /// NM_021806 /// XM_005274714 /// XM_005274716 /// XM_005277879 /// XM_006724831 /// XM_006724832 /// XM_006724833 /// XM_006724834 0005576 // extracellular region // inferred from electronic annotation 209406_at AF095192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF095192.1 /DEF=Homo sapiens BAG-family molecular chaperone regulator-2 mRNA, complete cds. /FEA=mRNA /PROD=BAG-family molecular chaperone regulator-2 /DB_XREF=gi:4322819 /UG=Hs.55220 BCL2-associated athanogene 2 /FL=gb:AF095192.1 gb:AL050287.1 gb:NM_004282.2 AF095192 BCL2-associated athanogene 2 BAG2 9532 NM_004282 /// XM_005249490 0006457 // protein folding // traceable author statement /// 0019538 // protein metabolic process // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation 209407_s_at AF068892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068892.1 /DEF=Homo sapiens Dukes type B colon adenocarcinoma truncated suppressin mRNA, complete cds. /FEA=mRNA /PROD=truncated suppressin /DB_XREF=gi:3293439 /UG=Hs.6574 deformed epidermal autoregulatory factor 1 (Drosophila) /FL=gb:NM_021008.1 gb:AF007165.1 gb:AF068892.1 gb:AF068893.1 gb:AF068894.1 gb:AF068895.1 gb:AF068896.1 gb:AF068897.1 gb:AF049460.1 AF068892 DEAF1 transcription factor DEAF1 10522 NM_001293634 /// NM_021008 /// XR_428838 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209408_at U63743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63743.1 /DEF=Homo sapiens mitotic centromere-associated kinesin mRNA, complete cds. /FEA=mRNA /PROD=mitotic centromere-associated kinesin /DB_XREF=gi:1695881 /UG=Hs.69360 kinesin-like 6 (mitotic centromere-associated kinesin) /FL=gb:NM_006845.2 gb:U63743.1 U63743 kinesin family member 2C KIF2C 11004 NM_006845 /// XM_005270394 /// XM_005270395 /// XM_005270396 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007019 // microtubule depolymerization // inferred from direct assay /// 0007019 // microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019237 // centromeric DNA binding // traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 209409_at D86962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86962.1 /DEF=Human mRNA for KIAA0207 gene, complete cds. /FEA=mRNA /GEN=KIAA0207 /DB_XREF=gi:1503997 /UG=Hs.81875 growth factor receptor-bound protein 10 /FL=gb:D86962.1 gb:AF000017.1 D86962 growth factor receptor-bound protein 10 GRB10 2887 NM_001001549 /// NM_001001550 /// NM_001001555 /// NM_005311 /// XM_005271760 /// XM_005271761 /// XM_005271765 /// XM_005271766 /// XM_005271767 /// XM_006715703 /// XM_006715704 /// XM_006715705 0007165 // signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 209410_s_at AF000017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000017.1 /DEF=Homo sapiens adapter protein (hGrb10zeta) mRNA, complete cds. /FEA=mRNA /GEN=hGrb10zeta /PROD=adapter protein /DB_XREF=gi:2130616 /UG=Hs.81875 growth factor receptor-bound protein 10 /FL=gb:D86962.1 gb:AF000017.1 AF000017 growth factor receptor-bound protein 10 GRB10 2887 NM_001001549 /// NM_001001550 /// NM_001001555 /// NM_005311 /// XM_005271760 /// XM_005271761 /// XM_005271765 /// XM_005271766 /// XM_005271767 /// XM_006715703 /// XM_006715704 /// XM_006715705 0007165 // signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 209411_s_at AW008018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW008018 /FEA=EST /DB_XREF=gi:5856796 /DB_XREF=est:wv48d07.x1 /CLONE=IMAGE:2532781 /UG=Hs.87726 KIAA0154 protein; ADP-ribosylation factor binding protein GGA3 /FL=gb:AF190864.1 gb:AF219139.1 AW008018 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 GGA3 23163 NM_001172703 /// NM_001172704 /// NM_001291641 /// NM_001291642 /// NM_014001 /// NM_138619 /// NR_033345 /// XM_006721784 /// XM_006721785 /// XR_429878 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 209412_at U61500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U61500.1 /DEF=Human GT334 protein (GT334) gene mRNA, complete cds. /FEA=mRNA /GEN=GT334 /PROD=GT334 protein /DB_XREF=gi:1778032 /UG=Hs.94479 transmembrane protein 1 /FL=gb:U61500.1 U61500 trafficking protein particle complex subunit 10-like /// trafficking protein particle complex 10 LOC102724200 /// TRAPPC10 7109 /// 102724200 NM_001001723 /// NM_003274 /// XM_005261168 /// XM_005261169 /// XM_006723912 /// XM_006724046 /// XM_006724047 0006810 // transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015081 // sodium ion transmembrane transporter activity // traceable author statement 209413_at BC002431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002431.1 /DEF=Homo sapiens, Similar to UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2, clone MGC:2008, mRNA, complete cds. /FEA=mRNA /PROD=Similar to UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2 /DB_XREF=gi:12803236 /UG=Hs.206713 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 /FL=gb:BC002431.1 gb:AF038660.1 gb:NM_003780.1 gb:AB024434.1 BC002431 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 B4GALT2 8704 NM_001005417 /// NM_003780 /// NM_030587 /// XM_005271304 /// XM_006711017 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0003945 // N-acetyllactosamine synthase activity // inferred from electronic annotation /// 0004461 // lactose synthase activity // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209414_at AI732960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732960 /FEA=EST /DB_XREF=gi:5054073 /DB_XREF=est:og97b04.x5 /CLONE=IMAGE:1456207 /UG=Hs.268384 Fzr1 protein /FL=gb:AF083810.1 gb:AB013462.1 gb:AF080397.1 gb:NM_016263.1 AI732960 fizzy/cell division cycle 20 related 1 (Drosophila) FZR1 51343 NM_001136197 /// NM_001136198 /// NM_016263 /// XM_005259573 /// XM_006722764 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // traceable author statement /// 0090344 // negative regulation of cell aging // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209415_at AA905473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA905473 /FEA=EST /DB_XREF=gi:3040596 /DB_XREF=est:ok01g02.s1 /CLONE=IMAGE:1506578 /UG=Hs.268384 Fzr1 protein /FL=gb:AF083810.1 gb:AB013462.1 gb:AF080397.1 gb:NM_016263.1 AA905473 fizzy/cell division cycle 20 related 1 (Drosophila) FZR1 51343 NM_001136197 /// NM_001136198 /// NM_016263 /// XM_005259573 /// XM_006722764 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // traceable author statement /// 0090344 // negative regulation of cell aging // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209416_s_at AF083810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083810.1 /DEF=Homo sapiens fizzy-related protein (FYR) mRNA, complete cds. /FEA=mRNA /GEN=FYR /PROD=fizzy-related protein /DB_XREF=gi:5813826 /UG=Hs.268384 Fzr1 protein /FL=gb:AF083810.1 gb:AB013462.1 gb:AF080397.1 gb:NM_016263.1 AF083810 fizzy/cell division cycle 20 related 1 (Drosophila) FZR1 51343 NM_001136197 /// NM_001136198 /// NM_016263 /// XM_005259573 /// XM_006722764 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // traceable author statement /// 0090344 // negative regulation of cell aging // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209417_s_at BC001356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001356.1 /DEF=Homo sapiens, Similar to interferon-induced protein 35, clone MGC:2935, mRNA, complete cds. /FEA=mRNA /PROD=Similar to interferon-induced protein 35 /DB_XREF=gi:12655016 /UG=Hs.50842 interferon-induced protein 35 /FL=gb:BC001356.1 BC001356 interferon-induced protein 35 IFI35 3430 NM_005533 /// XM_005257302 0006955 // immune response // non-traceable author statement /// 0009615 // response to virus // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 209418_s_at BC003615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003615.1 /DEF=Homo sapiens, gene from NF2meningioma region of 22q12, clone MGC:1540, mRNA, complete cds. /FEA=mRNA /PROD=gene from NF2meningioma region of 22q12 /DB_XREF=gi:13177658 /UG=Hs.75361 gene from NF2meningioma region of 22q12 /FL=gb:BC003615.1 gb:NM_003678.1 gb:AB023200.1 BC003615 THO complex 5 THOC5 8563 NM_001002877 /// NM_001002878 /// NM_001002879 /// NM_003678 /// XM_005261797 /// XM_005261798 /// XM_005261799 /// XM_005261800 /// XM_005261801 /// XM_006724347 /// XR_244394 /// XR_430413 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from sequence or structural similarity /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209419_at AB023200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB023200.1 /DEF=Homo sapiens mRNA for KIAA0983 protein, complete cds. /FEA=mRNA /GEN=KIAA0983 /PROD=KIAA0983 protein /DB_XREF=gi:4589609 /UG=Hs.75361 gene from NF2meningioma region of 22q12 /FL=gb:BC003615.1 gb:NM_003678.1 gb:AB023200.1 AB023200 THO complex 5 THOC5 8563 NM_001002877 /// NM_001002878 /// NM_001002879 /// NM_003678 /// XM_005261797 /// XM_005261798 /// XM_005261799 /// XM_005261800 /// XM_005261801 /// XM_006724347 /// XR_244394 /// XR_430413 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from sequence or structural similarity /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209420_s_at M59916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M59916.1 /DEF=Human acid sphingomyelinase (ASM) mRNA, complete cds. /FEA=mRNA /GEN=ASM /PROD=acid sphingomyelinase /DB_XREF=gi:179094 /UG=Hs.77813 sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) /FL=gb:M59916.1 gb:NM_000543.1 M59916 sphingomyelin phosphodiesterase 1, acid lysosomal SMPD1 6609 NM_000543 /// NM_001007593 /// NR_027400 /// XM_005253075 0006665 // sphingolipid metabolic process // traceable author statement /// 0006684 // sphingomyelin metabolic process // traceable author statement /// 0006685 // sphingomyelin catabolic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0042599 // lamellar body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 209421_at U04045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04045.1 /DEF=Human (hMSH2) mRNA, complete cds. /FEA=mRNA /GEN=hMSH2 /DB_XREF=gi:432997 /UG=Hs.78934 mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) /FL=gb:L47583.1 gb:L47582.1 gb:L47581.1 gb:U04045.1 gb:U03911.1 gb:NM_000251.1 U04045 mutS homolog 2 MSH2 4436 NM_000251 /// NM_001258281 /// XM_005264332 0000710 // meiotic mismatch repair // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002204 // somatic recombination of immunoglobulin genes involved in immune response // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006302 // double-strand break repair // not recorded /// 0006311 // meiotic gene conversion // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0008584 // male gonad development // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010165 // response to X-ray // inferred from sequence or structural similarity /// 0010224 // response to UV-B // not recorded /// 0010224 // response to UV-B // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0019724 // B cell mediated immunity // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0031573 // intra-S DNA damage checkpoint // not recorded /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045128 // negative regulation of reciprocal meiotic recombination // not recorded /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0045910 // negative regulation of DNA recombination // inferred from sequence or structural similarity /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000228 // nuclear chromosome // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0032302 // MutSbeta complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0000403 // Y-form DNA binding // not recorded /// 0000404 // heteroduplex DNA loop binding // not recorded /// 0000406 // double-strand/single-strand DNA junction binding // not recorded /// 0003677 // DNA binding // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from mutant phenotype /// 0032139 // dinucleotide insertion or deletion binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032181 // dinucleotide repeat insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay 209422_at AL109965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109965 /DEF=Human DNA sequence from clone RP5-1121G12 on chromosome 20 Contains the 3 end of a gene encoding two isoforms (the hepatocellular carcinoma-associated antigen 58 (HCA58) and a putative novel protein containing a PHD finger domain), the SCAND1 gen... /FEA=mRNA_2 /DB_XREF=gi:9663113 /UG=Hs.112594 hypothetical protein DKFZp434F0272 /FL=gb:AY027523.1 gb:AF348207.1 AL109965 PHD finger protein 20 PHF20 51230 NM_016436 /// XM_005260421 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 209423_s_at AY027523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY027523.1 /DEF=Homo sapiens transcription factor TZP (TZP) mRNA, complete cds. /FEA=mRNA /GEN=TZP /PROD=transcription factor TZP /DB_XREF=gi:13195150 /UG=Hs.112594 hypothetical protein DKFZp434F0272 /FL=gb:AY027523.1 gb:AF348207.1 AY027523 PHD finger protein 20 PHF20 51230 NM_016436 /// XM_005260421 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 209424_s_at AI796120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796120 /FEA=EST /DB_XREF=gi:5361583 /DB_XREF=est:wh42f03.x1 /CLONE=IMAGE:2383421 /UG=Hs.128749 alpha-methylacyl-CoA racemase /FL=gb:AF047020.1 gb:AF158378.1 gb:NM_014324.1 AI796120 alpha-methylacyl-CoA racemase /// C1QTNF3-AMACR readthrough (NMD candidate) AMACR /// C1QTNF3-AMACR 23600 /// 100534612 NM_001167595 /// NM_001167596 /// NM_001167597 /// NM_001167598 /// NM_014324 /// NM_203382 /// NR_037951 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0035356 // cellular triglyceride homeostasis // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045721 // negative regulation of gluconeogenesis // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0070165 // positive regulation of adiponectin secretion // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from direct assay /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from mutant phenotype /// 0016853 // isomerase activity // inferred from electronic annotation 209425_at AA888589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA888589 /FEA=EST /DB_XREF=gi:3004264 /DB_XREF=est:oe68e10.s1 /CLONE=IMAGE:1416810 /UG=Hs.128749 alpha-methylacyl-CoA racemase /FL=gb:AF047020.1 gb:AF158378.1 gb:NM_014324.1 AA888589 alpha-methylacyl-CoA racemase /// C1QTNF3-AMACR readthrough (NMD candidate) AMACR /// C1QTNF3-AMACR 23600 /// 100534612 NM_001167595 /// NM_001167596 /// NM_001167597 /// NM_001167598 /// NM_014324 /// NM_203382 /// NR_037951 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0035356 // cellular triglyceride homeostasis // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045721 // negative regulation of gluconeogenesis // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0070165 // positive regulation of adiponectin secretion // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from direct assay /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from mutant phenotype /// 0016853 // isomerase activity // inferred from electronic annotation 209426_s_at AF047020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047020.1 /DEF=Homo sapiens alpha-methylacyl-CoA racemase mRNA, complete cds. /FEA=mRNA /PROD=alpha-methylacyl-CoA racemase /DB_XREF=gi:4204096 /UG=Hs.128749 alpha-methylacyl-CoA racemase /FL=gb:AF047020.1 gb:AF158378.1 gb:NM_014324.1 AF047020 alpha-methylacyl-CoA racemase /// C1QTNF3-AMACR readthrough (NMD candidate) AMACR /// C1QTNF3-AMACR 23600 /// 100534612 NM_001167595 /// NM_001167596 /// NM_001167597 /// NM_001167598 /// NM_014324 /// NM_203382 /// NR_037951 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0035356 // cellular triglyceride homeostasis // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045721 // negative regulation of gluconeogenesis // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0070165 // positive regulation of adiponectin secretion // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from direct assay /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from mutant phenotype /// 0016853 // isomerase activity // inferred from electronic annotation 209427_at AF064238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064238.3 /DEF=Homo sapiens smoothelin large isoform L2 (SMTN) mRNA, complete cds. /FEA=mRNA /GEN=SMTN /PROD=smoothelin large isoform L2 /DB_XREF=gi:8119287 /UG=Hs.149098 smoothelin /FL=gb:AF064238.3 AF064238 smoothelin SMTN 6525 NM_001207017 /// NM_001207018 /// NM_006932 /// NM_134269 /// NM_134270 /// XM_006724298 /// XM_006724299 /// XM_006724300 /// XM_006724301 /// XM_006724302 /// XM_006724303 /// XM_006724304 /// XM_006724305 /// XM_006724306 /// XM_006724307 /// XR_430410 0006939 // smooth muscle contraction // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement 209428_s_at BG420865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG420865 /FEA=EST /DB_XREF=gi:13327371 /DB_XREF=est:602452067F1 /CLONE=IMAGE:4590353 /UG=Hs.155165 zinc finger protein-like 1 /FL=gb:AF001891.1 gb:AF043611.1 gb:NM_006782.1 gb:AF030291.1 BG420865 zinc finger protein-like 1 ZFPL1 7542 NM_006782 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209429_x_at AF112207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112207.1 /DEF=Homo sapiens translation initiation factor eIF-2b delta subunit mRNA, complete cds. /FEA=mRNA /PROD=translation initiation factor eIF-2b deltasubunit /DB_XREF=gi:6563201 /UG=Hs.169474 DKFZP586J0119 protein /FL=gb:BC001870.1 gb:AF112207.1 AF112207 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa EIF2B4 8890 NM_001034116 /// NM_015636 /// NM_172195 /// XM_005264632 /// XM_006712132 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // non-traceable author statement /// 0006446 // regulation of translational initiation // not recorded /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0032057 // negative regulation of translational initiation in response to stress // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // not recorded /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 209430_at AJ001017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001017.2 /DEF=Homo sapiens partial mRNA for TBP-associated factor 170 (TAFII170). /FEA=mRNA /GEN=TAFII170 /PROD=TBP associated factor /DB_XREF=gi:7018281 /UG=Hs.180930 TBP-associated factor 172 /FL=gb:AF038362.1 AJ001017 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa BTAF1 9044 NM_003972 /// XM_005270265 /// XM_005270266 /// XR_246113 0008152 // metabolic process // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209431_s_at AF254083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF254083.1 /DEF=Homo sapiens zinc finger sarcoma gene long A isoform (ZSG) mRNA, complete cds. /FEA=mRNA /GEN=ZSG /PROD=zinc finger sarcoma gene long A isoform /DB_XREF=gi:9954374 /UG=Hs.27801 zinc finger protein 278 /FL=gb:NM_014323.1 gb:AF254083.1 AF254083 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209432_s_at AF029674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029674.1 /DEF=Homo sapiens basic leucine zipper protein LZIP (LZIP) mRNA, complete cds. /FEA=mRNA /GEN=LZIP /PROD=basic leucine zipper protein LZIP /DB_XREF=gi:2599559 /UG=Hs.287921 cAMP responsive element binding protein 3 (luman) /FL=gb:AF211848.1 gb:AF009368.1 gb:AF029674.1 gb:NM_006368.1 AF029674 cAMP responsive element binding protein 3 CREB3 10488 NM_006368 0001558 // regulation of cell growth // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006990 // positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019043 // establishment of viral latency // inferred from direct assay /// 0019046 // release from viral latency // inferred from direct assay /// 0019046 // release from viral latency // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from direct assay /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090045 // positive regulation of deacetylase activity // inferred from direct assay /// 2000326 // negative regulation of ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // traceable author statement 209433_s_at AI457120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI457120 /FEA=EST /DB_XREF=gi:4309989 /DB_XREF=est:tl72b10.x1 /CLONE=IMAGE:2152603 /UG=Hs.311 phosphoribosyl pyrophosphate amidotransferase /FL=gb:U00238.1 AI457120 phosphoribosyl pyrophosphate amidotransferase PPAT 5471 NM_002703 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // traceable author statement /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004044 // amidophosphoribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 209434_s_at U00238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U00238.1 /DEF=Homo sapiens glutamine PRPP amidotransferase (GPAT) mRNA, complete cds. /FEA=mRNA /GEN=GPAT /PROD=glutamine PRPP amidotransferase /DB_XREF=gi:404860 /UG=Hs.311 phosphoribosyl pyrophosphate amidotransferase /FL=gb:U00238.1 U00238 phosphoribosyl pyrophosphate amidotransferase PPAT 5471 NM_002703 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // traceable author statement /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004044 // amidophosphoribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 209435_s_at BC000265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000265.1 /DEF=Homo sapiens, clone MGC:3182, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3182) /DB_XREF=gi:12653008 /UG=Hs.315417 Homo sapiens, clone MGC:3182, mRNA, complete cds /FL=gb:BC000265.1 BC000265 Rho/Rac guanine nucleotide exchange factor (GEF) 2 ARHGEF2 9181 NM_001162383 /// NM_001162384 /// NM_004723 /// XM_005245587 /// XM_005245588 /// XM_005245589 /// XM_005245590 /// XM_005245591 /// XM_005245592 /// XM_005245593 /// XM_005245594 /// XM_005245595 /// XM_006711622 /// XM_006711623 /// XM_006711624 /// XM_006711625 /// XM_006711626 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from sequence or structural similarity /// 0060547 // negative regulation of necrotic cell death // inferred from sequence or structural similarity /// 0071225 // cellular response to muramyl dipeptide // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0071474 // cellular hyperosmotic response // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from sequence or structural similarity /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // non-traceable author statement /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay 209436_at AB018305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018305.1 /DEF=Homo sapiens mRNA for KIAA0762 protein, partial cds. /FEA=mRNA /GEN=KIAA0762 /PROD=KIAA0762 protein /DB_XREF=gi:3882244 /UG=Hs.5378 spondin 1, (f-spondin) extracellular matrix protein /FL=gb:AB051390.1 AB018305 spondin 1, extracellular matrix protein SPON1 10418 NM_006108 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 209437_s_at AB051390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB051390.1 /DEF=Homo sapiens mRNA for VSGPF-spondin, complete cds. /FEA=mRNA /PROD=VSGPF-spondin /DB_XREF=gi:11320819 /UG=Hs.5378 spondin 1, (f-spondin) extracellular matrix protein /FL=gb:AB051390.1 AB051390 spondin 1, extracellular matrix protein SPON1 10418 NM_006108 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 209438_at AL096700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096700 /DEF=Human DNA sequence from clone RP3-499B10 on chromosome Xp22.31-22.13. Contains the 3 end of the gene for serinethreonine protein phosphatase PPEF, the 3 end of the PHKA2 gene for liver phosphorylase kinase alpha 2, ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:7077104 /UG=Hs.54941 phosphorylase kinase, alpha 2 (liver) /FL=gb:D38616.1 gb:NM_000292.1 AL096700 phosphorylase kinase, alpha 2 (liver) PHKA2 5256 NM_000292 /// XM_005274548 /// XM_005274550 /// XM_006724496 /// XM_006724497 /// XM_006724498 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 209439_s_at D38616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38616.1 /DEF=Human mRNA for phosphorylase kinase alpha subunit, complete cds. /FEA=mRNA /PROD=phosphorylase kinase alpha subunit /DB_XREF=gi:1304117 /UG=Hs.54941 phosphorylase kinase, alpha 2 (liver) /FL=gb:D38616.1 gb:NM_000292.1 D38616 phosphorylase kinase, alpha 2 (liver) PHKA2 5256 NM_000292 /// XM_005274548 /// XM_005274550 /// XM_006724496 /// XM_006724497 /// XM_006724498 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 209440_at BC001605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001605.1 /DEF=Homo sapiens, phosphoribosyl pyrophosphate synthetase 1, clone MGC:2256, mRNA, complete cds. /FEA=mRNA /PROD=phosphoribosyl pyrophosphate synthetase 1 /DB_XREF=gi:12804406 /UG=Hs.56 phosphoribosyl pyrophosphate synthetase 1 /FL=gb:BC001605.1 gb:D00860.1 BC001605 phosphoribosyl pyrophosphate synthetase 1 PRPS1 5631 NM_001204402 /// NM_002764 0005975 // carbohydrate metabolic process // traceable author statement /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // traceable author statement /// 0006144 // purine nucleobase metabolic process // inferred from mutant phenotype /// 0006164 // purine nucleotide biosynthetic process // inferred from mutant phenotype /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // non-traceable author statement /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034418 // urate biosynthetic process // inferred from mutant phenotype /// 0044249 // cellular biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046101 // hypoxanthine biosynthetic process // inferred from mutant phenotype 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // not recorded /// 0004749 // ribose phosphate diphosphokinase activity // inferred from direct assay /// 0004749 // ribose phosphate diphosphokinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209441_at AY009093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY009093.1 /DEF=Homo sapiens DBC2 (DBC2) mRNA, complete cds. /FEA=mRNA /GEN=DBC2 /PROD=DBC2 /DB_XREF=gi:12667515 /UG=Hs.62113 KIAA0717 protein /FL=gb:AY009093.1 AY009093 Rho-related BTB domain containing 2 RHOBTB2 23221 NM_001160036 /// NM_001160037 /// NM_015178 /// XM_006716315 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 209442_x_at AL136710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136710.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566P0524 (from clone DKFZp566P0524); complete cds. /FEA=mRNA /GEN=DKFZp566P0524 /PROD=hypothetical protein /DB_XREF=gi:12052939 /UG=Hs.75893 ankyrin 3, node of Ranvier (ankyrin G) /FL=gb:AL136710.1 AL136710 ankyrin 3, node of Ranvier (ankyrin G) ANK3 288 NM_001149 /// NM_001204403 /// NM_001204404 /// NM_020987 /// XM_005269715 /// XM_005269716 /// XM_006717782 /// XM_006717783 /// XM_006717784 /// XM_006717785 /// XM_006717786 /// XM_006717787 /// XM_006717788 /// XM_006717789 /// XM_006717790 /// XM_006717791 /// XM_006717792 /// XM_006717793 /// XM_006717794 /// XM_006717795 /// XM_006717796 /// XM_006717797 /// XM_006717798 /// XM_006717799 /// XM_006717800 /// XM_006717801 /// XM_006717802 /// XM_006717803 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010650 // positive regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045838 // positive regulation of membrane potential // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072660 // maintenance of protein location in plasma membrane // inferred from genetic interaction /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 1900827 // positive regulation of membrane depolarization during cardiac muscle cell action potential // inferred from sequence or structural similarity /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0014731 // spectrin-associated cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from sequence or structural similarity /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from sequence or structural similarity 209443_at J02639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02639.1 /DEF=Human plasma serine protease (protein C) inhibitor mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180549 /UG=Hs.76353 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 /FL=gb:NM_000624.1 gb:U35464.1 gb:J02639.1 gb:S58545.1 J02639 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 SERPINA5 5104 NM_000624 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007338 // single fertilization // inferred from electronic annotation /// 0007342 // fusion of sperm to egg plasma membrane // non-traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation 0002080 // acrosomal membrane // inferred from direct assay /// 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0036024 // protein C inhibitor-TMPRSS7 complex // inferred from direct assay /// 0036025 // protein C inhibitor-TMPRSS11E complex // inferred from direct assay /// 0036026 // protein C inhibitor-PLAT complex // inferred from direct assay /// 0036027 // protein C inhibitor-PLAU complex // inferred from direct assay /// 0036028 // protein C inhibitor-thrombin complex // inferred from direct assay /// 0036029 // protein C inhibitor-KLK3 complex // inferred from direct assay /// 0036030 // protein C inhibitor-plasma kallikrein complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097181 // protein C inhibitor-coagulation factor V complex // inferred from direct assay /// 0097182 // protein C inhibitor-coagulation factor Xa complex // inferred from direct assay /// 0097183 // protein C inhibitor-coagulation factor XI complex // inferred from direct assay 0001972 // retinoic acid binding // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0008201 // heparin binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0032190 // acrosin binding // inferred from physical interaction 209444_at BC001851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001851.1 /DEF=Homo sapiens, Similar to RAP1, GTP-GDP dissociation stimulator 1, clone MGC:4525, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RAP1, GTP-GDP dissociation stimulator1 /DB_XREF=gi:12804812 /UG=Hs.7940 RAP1, GTP-GDP dissociation stimulator 1 /FL=gb:NM_021159.1 gb:BC001851.1 gb:BC001816.1 gb:AF215923.1 gb:AF237413.1 BC001851 RAP1, GTP-GDP dissociation stimulator 1 RAP1GDS1 5910 NM_001100426 /// NM_001100427 /// NM_001100428 /// NM_001100429 /// NM_001100430 /// NM_021159 /// XM_006714284 /// XM_006714285 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0031034 // myosin filament assembly // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 209445_x_at AI765280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI765280 /FEA=EST /DB_XREF=gi:5231789 /DB_XREF=est:wi73a08.x1 /CLONE=IMAGE:2398934 /UG=Hs.8173 hypothetical protein FLJ10803 /FL=gb:BC001743.1 AI765280 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) COA1 55744 NM_018224 /// NR_047701 /// XM_005249804 /// XM_005249806 /// XM_005249807 /// XM_006715751 /// XM_006715752 /// XR_242093 /// XR_242094 /// XR_242095 /// XR_428082 /// XR_428083 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0033617 // mitochondrial respiratory chain complex IV assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 209446_s_at BC001743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001743.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ10803, clone MGC:933, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ10803 /DB_XREF=gi:12804636 /UG=Hs.8173 hypothetical protein FLJ10803 /FL=gb:BC001743.1 BC001743 209447_at AF043290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043290.1 /DEF=Homo sapiens lymphocyte membrane associated protein (8B7) mRNA, complete cds. /FEA=mRNA /GEN=8B7 /PROD=lymphocyte membrane associated protein /DB_XREF=gi:2895592 /UG=Hs.8182 synaptic nuclei expressed gene 1b /FL=gb:AF043290.1 AF043290 spectrin repeat containing, nuclear envelope 1 SYNE1 23345 NM_001099267 /// NM_001134379 /// NM_015293 /// NM_033071 /// NM_133650 /// NM_182961 /// XM_006715407 /// XM_006715408 /// XM_006715409 /// XM_006715410 /// XM_006715411 /// XM_006715412 /// XM_006715413 /// XM_006715414 /// XM_006715415 /// XM_006715416 /// XM_006715417 /// XM_006715418 /// XM_006715419 /// XM_006715420 /// XM_006715421 /// XM_006715422 /// XM_006715423 /// XM_006715424 /// XM_006715425 0006810 // transport // inferred from electronic annotation /// 0006997 // nucleus organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030017 // sarcomere // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity 209448_at BC002439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002439.1 /DEF=Homo sapiens, Tat-interacting protein (30kD), clone MGC:1318, mRNA, complete cds. /FEA=mRNA /PROD=Tat-interacting protein (30kD) /DB_XREF=gi:12803250 /UG=Hs.90753 Tat-interacting protein (30kD) /FL=gb:BC002439.1 gb:AF039103.1 BC002439 HIV-1 Tat interactive protein 2, 30kDa HTATIP2 10553 NM_001098520 /// NM_001098521 /// NM_001098522 /// NM_001098523 /// NM_006410 0001525 // angiogenesis // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 209449_at AF196468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF196468.1 /DEF=Homo sapiens SMX5-like protein mRNA, complete cds. /FEA=mRNA /PROD=SMX5-like protein /DB_XREF=gi:11225486 /UG=Hs.103106 U6 snRNA-associated Sm-like protein /FL=gb:NM_021177.1 gb:AF196468.1 gb:AF136977.1 gb:AF182288.1 AF196468 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM2 57819 NM_021177 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // non-traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209450_at AB050442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB050442.1 /DEF=Homo sapiens PRSMG1GCPL1 mRNA for putative metalloglycoprotease, complete cds. /FEA=mRNA /GEN=PRSMG1GCPL1 /PROD=putative metalloglycoprotease /DB_XREF=gi:13358863 /UG=Hs.108894 hypothetical protein FLJ20411 /FL=gb:AB050442.1 gb:NM_017807.1 AB050442 O-sialoglycoprotein endopeptidase OSGEP 55644 NM_017807 0008033 // tRNA processing // inferred from electronic annotation /// 0070526 // threonylcarbamoyladenosine biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209451_at U59863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59863.1 /DEF=Human TRAF-interacting protein I-TRAF mRNA, complete cds. /FEA=mRNA /PROD=I-TRAF /DB_XREF=gi:1518017 /UG=Hs.146847 TRAF family member-associated NFKB activator /FL=gb:U59863.1 U59863 TRAF family member-associated NFKB activator TANK 10010 NM_001199135 /// NM_004180 /// NM_133484 /// XM_005246206 /// XM_005246207 /// XM_005246208 /// XM_005246210 /// XM_005246211 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209452_s_at AF035824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035824.1 /DEF=Homo sapiens vesicle soluble NSF attachment protein receptor (VTI1) mRNA, complete cds. /FEA=mRNA /GEN=VTI1 /PROD=vesicle soluble NSF attachment protein receptor /DB_XREF=gi:2687399 /UG=Hs.169206 vesicle-associated soluble NSF attachment protein receptor (v-SNARE; homolog of S. cerevisiae VTI1) /FL=gb:BC003142.1 gb:AF035824.1 gb:AF060902.1 gb:NM_006370.1 AF035824 vesicle transport through interaction with t-SNAREs 1B VTI1B 10490 NM_006370 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000149 // SNARE binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 209453_at M81768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81768.1 /DEF=Human NaH antiporter (APNH1) mRNA, complete cds. /FEA=mRNA /GEN=APNH /PROD=NaH antiporter /DB_XREF=gi:178752 /UG=Hs.170222 solute carrier family 9 (sodiumhydrogen exchanger), isoform 1 (antiporter, Na+H+, amiloride sensitive) /FL=gb:M81768.1 gb:AF141350.1 gb:AF141351.1 gb:AF141352.1 gb:AF141353.1 gb:AF141354.1 gb:AF141355.1 gb:AF141356.1 gb:AF141357.1 gb:AF141358.1 gb:AF141359.1 gb:AF146430.1 gb:AF146431.1 gb:AF146432.1 gb:AF146433.1 gb:AF146434.1 gb:AF146435.1 gb:AF146436.1 gb:AF146437.1 gb:AF146438.1 gb:AF146439.1 M81768 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 SLC9A1 6548 NM_003047 /// NR_046474 0001101 // response to acid // inferred from direct assay /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from direct assay /// 0006885 // regulation of pH // traceable author statement /// 0010447 // response to acidity // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035794 // positive regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from sequence or structural similarity /// 0051453 // regulation of intracellular pH // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070997 // neuron death // inferred from electronic annotation /// 0071436 // sodium ion export // inferred from sequence or structural similarity /// 0071468 // cellular response to acidity // inferred from sequence or structural similarity /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // traceable author statement /// 0015385 // sodium:proton antiporter activity // inferred from direct assay /// 0015385 // sodium:proton antiporter activity // inferred from sequence or structural similarity /// 0015386 // potassium:proton antiporter activity // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from direct assay 209454_s_at AF142482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF142482.1 /DEF=Homo sapiens transcription enhancer factor-5 mRNA, complete cds. /FEA=mRNA /PROD=transcription enhancer factor-5 /DB_XREF=gi:4755000 /UG=Hs.203846 TEA domain family member 3 /FL=gb:AF142482.1 AF142482 TEA domain family member 3 TEAD3 7005 NM_003214 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0035329 // hippo signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209455_at BE963245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963245 /FEA=EST /DB_XREF=gi:11766663 /DB_XREF=est:601656874R1 /CLONE=IMAGE:3865699 /UG=Hs.21229 f-box and WD-40 domain protein 1B /FL=gb:AF176022.1 gb:AB033281.1 BE963245 F-box and WD repeat domain containing 11 FBXW11 23291 NM_012300 /// NM_033644 /// NM_033645 /// XM_005265855 /// XM_005265856 /// XM_005265857 /// XM_005265858 /// XM_005265859 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209456_s_at AB033281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB033281.1 /DEF=Homo sapiens BTRCP2 mRNA for F-box and WD-repeats protein isoform C, complete cds. /FEA=mRNA /GEN=BTRCP2 /PROD=F-box and WD-repeats protein beta-TRCP2 isoformC /DB_XREF=gi:7209812 /UG=Hs.21229 f-box and WD-40 domain protein 1B /FL=gb:AF176022.1 gb:AB033281.1 AB033281 F-box and WD repeat domain containing 11 FBXW11 23291 NM_012300 /// NM_033644 /// NM_033645 /// XM_005265855 /// XM_005265856 /// XM_005265857 /// XM_005265858 /// XM_005265859 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209457_at U16996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16996.1 /DEF=Human protein tyrosine phosphatase mRNA, complete cds. /FEA=mRNA /PROD=protein tyrosine phosphatase /DB_XREF=gi:642012 /UG=Hs.2128 dual specificity phosphatase 5 /FL=gb:NM_004419.2 gb:U16996.1 gb:U15932.2 U16996 dual specificity phosphatase 5 DUSP5 1847 NM_004419 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 209458_x_at AF105974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF105974.1 /DEF=Homo sapiens alpha one globin (HBA1) mRNA, complete cds. /FEA=mRNA /GEN=HBA1 /PROD=alpha one globin /DB_XREF=gi:4038449 /UG=Hs.272572 hemoglobin, alpha 2 /FL=gb:AF097635.1 gb:AF105974.1 gb:NM_000517.2 AF105974 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209459_s_at AF237813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF237813.1 /DEF=Homo sapiens NPD009 mRNA, complete cds. /FEA=mRNA /PROD=NPD009 /DB_XREF=gi:9963907 /UG=Hs.283675 NPD009 protein /FL=gb:NM_020686.1 gb:AF237813.1 AF237813 4-aminobutyrate aminotransferase ABAT 18 NM_000663 /// NM_001127448 /// NM_020686 /// XM_005255154 0001666 // response to hypoxia // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007620 // copulation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // non-traceable author statement /// 0010039 // response to iron ion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // non-traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0032144 // 4-aminobutyrate transaminase complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003867 // 4-aminobutyrate transaminase activity // inferred from direct assay /// 0003867 // 4-aminobutyrate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0032145 // succinate-semialdehyde dehydrogenase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047298 // (S)-3-amino-2-methylpropionate transaminase activity // inferred from electronic annotation 209460_at AF237813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF237813.1 /DEF=Homo sapiens NPD009 mRNA, complete cds. /FEA=mRNA /PROD=NPD009 /DB_XREF=gi:9963907 /UG=Hs.283675 NPD009 protein /FL=gb:NM_020686.1 gb:AF237813.1 AF237813 4-aminobutyrate aminotransferase ABAT 18 NM_000663 /// NM_001127448 /// NM_020686 /// XM_005255154 0001666 // response to hypoxia // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007620 // copulation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // non-traceable author statement /// 0010039 // response to iron ion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // non-traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0032144 // 4-aminobutyrate transaminase complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003867 // 4-aminobutyrate transaminase activity // inferred from direct assay /// 0003867 // 4-aminobutyrate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0032145 // succinate-semialdehyde dehydrogenase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047298 // (S)-3-amino-2-methylpropionate transaminase activity // inferred from electronic annotation 209461_x_at BC001648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001648.1 /DEF=Homo sapiens, clone MGC:2436, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2436) /DB_XREF=gi:12804480 /UG=Hs.325321 hypothetical protein R32184_1 /FL=gb:BC001648.1 BC001648 WD repeat domain 18 WDR18 57418 NM_024100 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209462_at U48437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U48437.1 /DEF=Human amyloid precursor-like protein 1 mRNA, complete cds. /FEA=mRNA /PROD=amyloid precursor-like protein 1 /DB_XREF=gi:1709300 /UG=Hs.74565 amyloid beta (A4) precursor-like protein 1 /FL=gb:U48437.1 gb:NM_005166.1 U48437 amyloid beta (A4) precursor-like protein 1 APLP1 333 NM_001024807 /// NM_005166 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred by curator /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0071874 // cellular response to norepinephrine stimulus // inferred from direct assay 0005604 // basement membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from physical interaction /// 0031695 // alpha-2B adrenergic receptor binding // inferred from physical interaction /// 0031696 // alpha-2C adrenergic receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 209463_s_at D50544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50544.1 /DEF=Human TFIID subunit p22 mRNA, complete cds. /FEA=mRNA /PROD=TFIID subunit p22 /DB_XREF=gi:1345403 /UG=Hs.82037 TATA box binding protein (TBP)-associated factor, RNA polymerase II, J, 20kD /FL=gb:D50544.1 gb:NM_005644.2 D50544 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa TAF12 6883 NM_001135218 /// NM_005644 /// XM_005245978 /// XM_005245979 /// XM_006710860 /// XM_006710861 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0000125 // PCAF complex // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0030914 // STAGA complex // inferred from electronic annotation /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209464_at AB011446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB011446.1 /DEF=Homo sapiens mRNA for Aik2, complete cds. /FEA=mRNA /GEN=aik2 /PROD=Aik2 /DB_XREF=gi:5688865 /UG=Hs.180655 serinethreonine kinase 12 /FL=gb:BC000442.1 gb:AF004022.1 gb:AF008552.1 gb:AB011450.1 gb:AF015254.1 gb:NM_004217.1 gb:AB011446.1 AB011446 aurora kinase B AURKB 9212 NM_001256834 /// NM_001284526 /// NM_004217 /// XM_005256854 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // traceable author statement /// 0009838 // abscission // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016570 // histone modification // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031565 // cytokinesis checkpoint // inferred from sequence or structural similarity /// 0031577 // spindle checkpoint // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032466 // negative regulation of cytokinesis // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from mutant phenotype /// 0034644 // cellular response to UV // inferred from direct assay /// 0036089 // cleavage furrow formation // inferred from direct assay /// 0043146 // spindle stabilization // inferred from mutant phenotype /// 0043988 // histone H3-S28 phosphorylation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // traceable author statement /// 0051256 // spindle midzone assembly involved in mitosis // inferred from mutant phenotype /// 0051256 // spindle midzone assembly involved in mitosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000779 // condensed chromosome, centromeric region // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010369 // chromocenter // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0032133 // chromosome passenger complex // inferred from physical interaction /// 0032133 // chromosome passenger complex // traceable author statement /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035174 // histone serine kinase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209465_x_at AL565812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565812 /FEA=EST /DB_XREF=gi:12917557 /DB_XREF=est:AL565812 /CLONE=CS0DF008YL14 (3 prime) /UG=Hs.44 pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) /FL=gb:M57399.1 AL565812 pleiotrophin PTN 5764 NM_002825 /// XM_005250515 /// XM_005250516 0001503 // ossification // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 209466_x_at M57399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57399.1 /DEF=Human nerve growth factor (HBNF-1) mRNA, complete cds. /FEA=mRNA /GEN=HBNF-1 /PROD=nerve growth factor /DB_XREF=gi:292072 /UG=Hs.44 pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) /FL=gb:M57399.1 M57399 pleiotrophin PTN 5764 NM_002825 /// XM_005250515 /// XM_005250516 0001503 // ossification // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 209467_s_at BC002755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002755.1 /DEF=Homo sapiens, Similar to MAP kinase-interacting serinethreonine kinase 1, clone MGC:3690, mRNA, complete cds. /FEA=mRNA /PROD=Similar to MAP kinase-interactingserinethreonine kinase 1 /DB_XREF=gi:12803828 /UG=Hs.5591 MAP kinase-interacting serinethreonine kinase 1 /FL=gb:BC002755.1 BC002755 MAP kinase interacting serine/threonine kinase 1 MKNK1 8569 NM_001135553 /// NM_003684 /// NM_198973 /// NR_024174 /// NR_024175 /// NR_024176 /// XM_006710999 /// XM_006711000 /// XM_006711001 /// XM_006711002 /// XM_006711003 /// XM_006711004 /// XM_006711005 /// XM_006711006 /// XM_006711007 /// XM_006711008 /// XM_006711009 /// XM_006711010 /// XM_006711011 /// XM_006711012 /// XM_006711013 /// XM_006711014 /// XM_006711015 /// XR_426637 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 209468_at AB017498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017498.1 /DEF=Homo sapiens LRP5 mRNA for Lipoprotein Receptor Related Protein 5, complete cds. /FEA=mRNA /GEN=LRP5 /PROD=Lipoprotein Receptor Related Protein 5 /DB_XREF=gi:3582144 /UG=Hs.6347 low density lipoprotein receptor-related protein 5 /FL=gb:AB017498.1 gb:AF064548.1 gb:AF077820.1 gb:NM_002335.1 AB017498 low density lipoprotein receptor-related protein 5 LRP5 4041 NM_001291902 /// NM_002335 /// XM_005273994 0001702 // gastrulation with mouth forming second // not recorded /// 0001944 // vasculature development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from mutant phenotype /// 0002076 // osteoblast development // not recorded /// 0006007 // glucose catabolic process // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // not recorded /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // not recorded /// 0033690 // positive regulation of osteoblast proliferation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035426 // extracellular matrix-cell signaling // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 0045600 // positive regulation of fat cell differentiation // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046849 // bone remodeling // not recorded /// 0046850 // regulation of bone remodeling // inferred from electronic annotation /// 0048539 // bone marrow development // inferred from mutant phenotype /// 0048596 // embryonic camera-type eye morphogenesis // not recorded /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from mutant phenotype /// 0060059 // embryonic retina morphogenesis in camera-type eye // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from mutant phenotype /// 0060444 // branching involved in mammary gland duct morphogenesis // not recorded /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from mutant phenotype /// 0060764 // cell-cell signaling involved in mammary gland development // inferred from electronic annotation /// 0060828 // regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // not recorded /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from mutant phenotype /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // not recorded /// 0017147 // Wnt-protein binding // not recorded /// 0019534 // toxin transporter activity // inferred from mutant phenotype /// 0042813 // Wnt-activated receptor activity // not recorded 209469_at BF939489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939489 /FEA=EST /DB_XREF=gi:12356809 /DB_XREF=est:nac76h10.x1 /CLONE=IMAGE:3440491 /UG=Hs.75819 glycoprotein M6A /FL=gb:D49958.1 BF939489 glycoprotein M6A GPM6A 2823 NM_001261447 /// NM_001261448 /// NM_005277 /// NM_201591 /// NM_201592 /// NR_048571 /// XM_006714183 0001764 // neuron migration // inferred from direct assay /// 0003407 // neural retina development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209470_s_at D49958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D49958.1 /DEF=Homo sapiens mRNA for membrane glycoprotein M6, complete cds. /FEA=mRNA /PROD=membrane glycoprotein M6 /DB_XREF=gi:1663516 /UG=Hs.75819 glycoprotein M6A /FL=gb:D49958.1 D49958 glycoprotein M6A GPM6A 2823 NM_001261447 /// NM_001261448 /// NM_005277 /// NM_201591 /// NM_201592 /// NR_048571 /// XM_006714183 0001764 // neuron migration // inferred from direct assay /// 0003407 // neural retina development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209471_s_at L00634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L00634.1 /DEF=Human farnesyl-protein transferase alpha-subunit mRNA, complete cds. /FEA=mRNA /PROD=farnesyl-protein transferase alpha-subunit /DB_XREF=gi:292030 /UG=Hs.138381 farnesyltransferase, CAAX box, alpha /FL=gb:L00634.1 gb:L10413.1 gb:NM_002027.1 L00634 farnesyltransferase, CAAX box, alpha FNTA 2339 NM_001018676 /// NM_001018677 /// NM_002027 /// NR_033698 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018343 // protein farnesylation // inferred from direct assay /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0090044 // positive regulation of tubulin deacetylation // inferred from direct assay /// 0090045 // positive regulation of deacetylase activity // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005953 // CAAX-protein geranylgeranyltransferase complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0004661 // protein geranylgeranyltransferase activity // inferred from direct assay /// 0004662 // CAAX-protein geranylgeranyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 209472_at BC000819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000819.1 /DEF=Homo sapiens, Similar to CG6950 gene product, clone MGC:5114, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG6950 gene product /DB_XREF=gi:12654030 /UG=Hs.180378 hypothetical protein 669 /FL=gb:BC000819.1 gb:NM_019610.1 BC000819 cysteine conjugate-beta lyase 2 CCBL2 56267 NM_001008661 /// NM_001008662 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from sequence or structural similarity /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070189 // kynurenine metabolic process // inferred from sequence or structural similarity /// 0097052 // L-kynurenine metabolic process // inferred from electronic annotation /// 0097052 // L-kynurenine metabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016212 // kynurenine-oxoglutarate transaminase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047315 // kynurenine-glyoxylate transaminase activity // inferred from sequence or structural similarity /// 0047804 // cysteine-S-conjugate beta-lyase activity // inferred from electronic annotation 209473_at AV717590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV717590 /FEA=EST /DB_XREF=gi:10814742 /DB_XREF=est:AV717590 /CLONE=DCBCFE01 /UG=Hs.205353 ectonucleoside triphosphate diphosphohydrolase 1 /FL=gb:U87967.1 AV717590 ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 953 NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation 0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209474_s_at U87967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87967.1 /DEF=Human ATP diphosphohydrolase mRNA, complete cds. /FEA=mRNA /PROD=ATP diphosphohydrolase /DB_XREF=gi:1842119 /UG=Hs.205353 ectonucleoside triphosphate diphosphohydrolase 1 /FL=gb:U87967.1 U87967 ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 953 NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation 0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209475_at AF106069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF106069.1 /DEF=Homo sapiens deubiquitinating enzyme (UNPH4) mRNA, complete cds. /FEA=mRNA /GEN=UNPH4 /PROD=deubiquitinating enzyme /DB_XREF=gi:5814096 /UG=Hs.23168 ubiquitin specific protease 15 /FL=gb:AF013990.1 gb:AF106069.1 AF106069 microRNA 6125 /// ubiquitin specific peptidase 15 MIR6125 /// USP15 9958 /// 102465133 NM_001252078 /// NM_001252079 /// NM_006313 /// NR_106740 /// XM_005269259 /// XM_005269261 /// XM_006719718 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0035520 // monoubiquitinated protein deubiquitination // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction 209476_at AL080080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080080.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E1962 (from clone DKFZp564E1962); partial cds. /FEA=mRNA /GEN=DKFZp564E1962 /PROD=hypothetical protein /DB_XREF=gi:5262491 /UG=Hs.24766 thioredoxin-related transmembrane protein /FL=gb:AB048246.1 AL080080 thioredoxin-related transmembrane protein 1 TMX1 81542 NM_030755 0006260 // DNA replication // non-traceable author statement /// 0006457 // protein folding // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045321 // leukocyte activation // non-traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045927 // positive regulation of growth // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded /// 0015036 // disulfide oxidoreductase activity // inferred from direct assay /// 0030612 // arsenate reductase (thioredoxin) activity // non-traceable author statement 209477_at BC000738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000738.1 /DEF=Homo sapiens, emerin (Emery-Dreifuss muscular dystrophy), clone MGC:2126, mRNA, complete cds. /FEA=mRNA /PROD=emerin (Emery-Dreifuss muscular dystrophy) /DB_XREF=gi:12653890 /UG=Hs.2985 emerin (Emery-Dreifuss muscular dystrophy) /FL=gb:BC000738.1 gb:NM_000117.1 BC000738 emerin EMD 2010 NM_000117 0000278 // mitotic cell cycle // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0060828 // regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay 209478_at U95006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U95006.1 /DEF=Human D9 splice variant A mRNA, complete cds. /FEA=mRNA /PROD=D9 splice variant A /DB_XREF=gi:2071992 /UG=Hs.37616 Human D9 splice variant B mRNA, complete cds /FL=gb:U95006.1 gb:U95007.1 U95006 stimulated by retinoic acid 13 STRA13 201254 NM_001271006 /// NM_001271007 /// NM_144998 /// XM_005256339 0000712 // resolution of meiotic recombination intermediates // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay /// 0071821 // FANCM-MHF complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209479_at BC000758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000758.1 /DEF=Homo sapiens, clone MGC:2698, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2698) /DB_XREF=gi:12653928 /UG=Hs.44468 DKFZP586D0623 protein /FL=gb:BC000758.1 BC000758 coiled-coil domain containing 28A CCDC28A 25901 NM_015439 209480_at M16276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M16276.1 /DEF=Human MHC class II HLA-DR2-Dw12 mRNA DQw1-beta, complete cds. /FEA=mRNA /GEN=HLA-DRB2 /DB_XREF=gi:188397 /UG=Hs.73931 major histocompatibility complex, class II, DQ beta 1 /FL=gb:M60028.1 gb:M17564.1 gb:M81140.1 gb:M81141.1 gb:M16276.1 gb:NM_002123.1 M16276 major histocompatibility complex, class II, DQ beta 1 HLA-DQB1 3119 NM_001243961 /// NM_001243962 /// NM_002123 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 209481_at AF226044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF226044.1 /DEF=Homo sapiens HSNFRK (HSNFRK) mRNA, complete cds. /FEA=mRNA /GEN=HSNFRK /PROD=HSNFRK /DB_XREF=gi:9295326 /UG=Hs.79025 KIAA0096 protein /FL=gb:AF226044.1 AF226044 SNF related kinase SNRK 54861 NM_001100594 /// NM_017719 /// XM_005265245 /// XM_005265246 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209482_at BC001430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001430.1 /DEF=Homo sapiens, POP7 (processing of precursor, S. cerevisiae) homolog, clone MGC:1986, mRNA, complete cds. /FEA=mRNA /PROD=POP7 (processing of precursor, S. cerevisiae)homolog /DB_XREF=gi:12655150 /UG=Hs.18747 POP7 (processing of precursor, S. cerevisiae) homolog /FL=gb:BC001430.1 gb:U94316.1 gb:NM_005837.1 BC001430 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) POP7 10248 NM_005837 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005634 // nucleus // traceable author statement /// 0005655 // nucleolar ribonuclease P complex // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209483_s_at AF255793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF255793.1 /DEF=Homo sapiens DC31 mRNA, complete cds. /FEA=mRNA /PROD=DC31 /DB_XREF=gi:12005828 /UG=Hs.24427 DKFZP566O1646 protein /FL=gb:AF255793.1 gb:AF201941.1 AF255793 NSL1, MIS12 kinetochore complex component NSL1 25936 NM_001042549 /// NM_015471 /// XM_006711267 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 209484_s_at AF201941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201941.1 /DEF=Homo sapiens DC8 (DC8) mRNA, complete cds. /FEA=mRNA /GEN=DC8 /PROD=DC8 /DB_XREF=gi:9295185 /UG=Hs.24427 DKFZP566O1646 protein /FL=gb:AF255793.1 gb:AF201941.1 AF201941 NSL1, MIS12 kinetochore complex component NSL1 25936 NM_001042549 /// NM_015471 /// XM_006711267 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209485_s_at W19983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W19983 /FEA=EST /DB_XREF=gi:1295853 /DB_XREF=est:zb38d10.r1 /CLONE=IMAGE:305875 /UG=Hs.252716 Homo sapiens oxysterol-binding protein-related protein (ORP1) mRNA, complete cds /FL=gb:AF274714.1 W19983 oxysterol binding protein-like 1A OSBPL1A 114876 NM_001242508 /// NM_018030 /// NM_080597 /// NM_133268 /// XM_006722380 /// XM_006722381 /// XM_006722382 /// XM_006722383 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 209486_at BC004546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004546.1 /DEF=Homo sapiens, disrupter of silencing 10, clone MGC:11290, mRNA, complete cds. /FEA=mRNA /PROD=disrupter of silencing 10 /DB_XREF=gi:13528698 /UG=Hs.322901 disrupter of silencing 10 /FL=gb:AL136590.1 gb:BC004546.1 gb:AF271212.1 gb:NM_020368.1 BC004546 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) UTP3 57050 NM_020368 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209487_at D84109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D84109.1 /DEF=Homo sapiens mRNA for RBP-MStype 3, complete cds. /FEA=mRNA /GEN=RBP-MS /PROD=RBP-MStype 3 /DB_XREF=gi:1669550 /UG=Hs.80248 RNA-binding protein gene with multiple splicing /FL=gb:BC003608.1 gb:D84109.1 D84109 RNA binding protein with multiple splicing RBPMS 11030 NM_001008710 /// NM_001008711 /// NM_001008712 /// NM_006867 /// XM_005273386 /// XM_005273390 /// XM_006716277 /// XM_006716278 /// XM_006716279 /// XR_428303 /// XR_428304 /// XR_428305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209488_s_at D84109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D84109.1 /DEF=Homo sapiens mRNA for RBP-MStype 3, complete cds. /FEA=mRNA /GEN=RBP-MS /PROD=RBP-MStype 3 /DB_XREF=gi:1669550 /UG=Hs.80248 RNA-binding protein gene with multiple splicing /FL=gb:BC003608.1 gb:D84109.1 D84109 RNA binding protein with multiple splicing RBPMS 11030 NM_001008710 /// NM_001008711 /// NM_001008712 /// NM_006867 /// XM_005273386 /// XM_005273390 /// XM_006716277 /// XM_006716278 /// XM_006716279 /// XR_428303 /// XR_428304 /// XR_428305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209489_at N25915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25915 /FEA=EST /DB_XREF=gi:1140263 /DB_XREF=est:yx87a02.s1 /CLONE=IMAGE:268682 /UG=Hs.81248 CUG triplet repeat, RNA-binding protein 1 /FL=gb:AF248648.1 N25915 CUGBP, Elav-like family member 1 CELF1 10658 NM_001025596 /// NM_001172639 /// NM_001172640 /// NM_006560 /// NM_198700 /// XM_005252754 /// XM_005252755 /// XM_005252756 /// XM_006718122 /// XM_006718123 /// XM_006718124 /// XM_006718125 /// XM_006718126 /// XM_006718127 /// XM_006718128 /// XM_006718129 /// XM_006718130 /// XM_006718131 0006376 // mRNA splice site selection // inferred from sequence or structural similarity /// 0006397 // mRNA processing // traceable author statement /// 0007281 // germ cell development // non-traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016246 // RNA interference // non-traceable author statement /// 0017148 // negative regulation of translation // non-traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0042835 // BRE binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 209490_s_at AF020543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020543.1 /DEF=Homo sapiens palmitoyl-protein thioesterase-2 (PPT2) mRNA, complete cds. /FEA=mRNA /GEN=PPT2 /PROD=palmitoyl-protein thioesterase-2 /DB_XREF=gi:2501960 /UG=Hs.81737 palmitoyl-protein thioesterase 2 /FL=gb:BC001355.1 gb:AF020543.1 AF020543 EGF-like-domain, multiple 8 /// palmitoyl-protein thioesterase 2 EGFL8 /// PPT2 9374 /// 80864 NM_001204103 /// NM_005155 /// NM_030652 /// NM_138717 /// NM_138934 /// NR_037860 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0008474 // palmitoyl-(protein) hydrolase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // non-traceable author statement 209491_s_at AA919119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA919119 /FEA=EST /DB_XREF=gi:3059009 /DB_XREF=est:ol85h03.s1 /CLONE=IMAGE:1536437 /UG=Hs.83918 adenosine monophosphate deaminase (isoform E) /FL=gb:M84721.1 gb:D12775.1 AA919119 adenosine monophosphate deaminase 3 /// uncharacterized LOC100130460 AMPD3 /// CAND1.11 272 /// 100130460 NM_000480 /// NM_001025389 /// NM_001025390 /// NM_001172430 /// NM_001172431 /// NR_103765 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006188 // IMP biosynthetic process // inferred from electronic annotation /// 0006196 // AMP catabolic process // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0032264 // IMP salvage // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003876 // AMP deaminase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209492_x_at BC003679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003679.1 /DEF=Homo sapiens, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e, clone MGC:12532, mRNA, complete cds. /FEA=mRNA /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit e /DB_XREF=gi:13277543 /UG=Hs.85539 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e /FL=gb:BC003679.1 BC003679 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E ATP5I 521 NM_007100 /// NR_033743 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 209493_at AF338650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF338650.1 /DEF=Homo sapiens PDZ domain-containing protein AIPC (AIPC) mRNA, complete cds. /FEA=mRNA /GEN=AIPC /PROD=PDZ domain-containing protein AIPC /DB_XREF=gi:12751451 /UG=Hs.173035 KIAA0300 protein /FL=gb:AF338650.1 AF338650 PDZ domain containing 2 PDZD2 23037 NM_015022 /// NM_178140 /// XM_005248269 /// XM_005248270 /// XM_005248271 /// XM_005248272 /// XM_006714456 /// XM_006714457 /// XM_006714458 /// XM_006714459 /// XM_006714460 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 209494_s_at AI807017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI807017 /FEA=EST /DB_XREF=gi:5393583 /DB_XREF=est:wf37b07.x1 /CLONE=IMAGE:2357749 /UG=Hs.27801 zinc finger protein 278 /FL=gb:AF254086.1 AI807017 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209495_at AF022655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022655.1 /DEF=Homo sapiens cep250 centrosome associated protein mRNA, complete cds. /FEA=mRNA /PROD=cep250 centrosome associated protein /DB_XREF=gi:2832236 /UG=Hs.27910 centrosomal protein 2 /FL=gb:AF022655.1 gb:AF049105.1 gb:NM_007186.1 AF022655 centrosomal protein 250kDa CEP250 11190 NM_001035518 /// NM_007186 /// XM_005260262 /// XM_005260263 /// XM_005260264 /// XM_005260265 /// XM_006723690 /// XM_006723691 /// XM_006723692 /// XM_006723693 /// XM_006723694 /// XM_006723695 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0030997 // regulation of centriole-centriole cohesion // inferred from direct assay /// 0033365 // protein localization to organelle // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 209496_at BC000069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000069.1 /DEF=Homo sapiens, retinoic acid receptor responder (tazarotene induced) 2, clone MGC:1544, mRNA, complete cds. /FEA=mRNA /PROD=retinoic acid receptor responder (tazaroteneinduced) 2 /DB_XREF=gi:12652642 /UG=Hs.37682 retinoic acid receptor responder (tazarotene induced) 2 /FL=gb:BC000069.1 gb:U77594.1 gb:AB015632.1 gb:NM_002889.2 BC000069 retinoic acid receptor responder (tazarotene induced) 2 RARRES2 5919 NM_002889 /// XM_005250033 0001523 // retinoid metabolic process // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from expression pattern /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0010759 // positive regulation of macrophage chemotaxis // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0050994 // regulation of lipid catabolic process // inferred from sequence or structural similarity /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 209497_s_at BC003503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003503.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 4921506I22 gene, clone MGC:10380, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 4921506I22 gene /DB_XREF=gi:13097557 /UG=Hs.49994 Homo sapiens, clone MGC:10871, mRNA, complete cds /FL=gb:BC003503.1 gb:BC004951.1 BC003503 RNA binding motif protein 4B RBM4B 83759 NM_001286135 /// NM_031492 /// XR_247213 /// XR_247214 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209498_at X16354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16354.1 /DEF=Human mRNA for transmembrane carcinoembryonic antigen BGPa (formerly TM1-CEA). /FEA=mRNA /PROD=TM1-CEA preprotein /DB_XREF=gi:37197 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:J03858.1 X16354 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) CEACAM1 634 NM_001024912 /// NM_001184813 /// NM_001184815 /// NM_001184816 /// NM_001205344 /// NM_001712 0001525 // angiogenesis // non-traceable author statement /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 209499_x_at BF448647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448647 /FEA=EST /DB_XREF=gi:11514815 /DB_XREF=est:7n90g02.x1 /CLONE=IMAGE:3572138 /UG=Hs.54673 tumor necrosis factor (ligand) superfamily, member 13 /FL=gb:AF114012.1 BF448647 TNFSF12-TNFSF13 readthrough /// tumor necrosis factor (ligand) superfamily, member 13 TNFSF12-TNFSF13 /// TNFSF13 8741 /// 407977 NM_001198622 /// NM_001198623 /// NM_001198624 /// NM_003808 /// NM_172087 /// NM_172088 /// NM_172089 /// NR_073490 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 209500_x_at AF114012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114012.1 /DEF=Homo sapiens tumor necrosis factor-related death ligand-1beta mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor-related deathligand-1beta /DB_XREF=gi:7328555 /UG=Hs.54673 tumor necrosis factor (ligand) superfamily, member 13 /FL=gb:AF114012.1 AF114012 TNFSF12-TNFSF13 readthrough /// tumor necrosis factor (ligand) superfamily, member 13 TNFSF12-TNFSF13 /// TNFSF13 8741 /// 407977 NM_001198622 /// NM_001198623 /// NM_001198624 /// NM_003808 /// NM_172087 /// NM_172088 /// NM_172089 /// NR_073490 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 209501_at AL582414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL582414 /FEA=EST /DB_XREF=gi:12950373 /DB_XREF=est:AL582414 /CLONE=CS0DL001YM17 (3 prime) /UG=Hs.75124 cerebellar degeneration-related protein (62kD) /FL=gb:D12981.1 AL582414 cerebellar degeneration-related protein 2, 62kDa /// cerebellar degeneration-related protein 2-like CDR2 /// LOC101060399 1039 /// 101060399 NM_001802 /// XM_005276502 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209502_s_at BC002495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002495.1 /DEF=Homo sapiens, Similar to BAI1-associated protein 2, clone MGC:1836, mRNA, complete cds. /FEA=mRNA /PROD=Similar to BAI1-associated protein 2 /DB_XREF=gi:12803352 /UG=Hs.7936 BAI1-associated protein 2 /FL=gb:BC002495.1 BC002495 BAI1-associated protein 2 BAIAP2 10458 NM_001144888 /// NM_006340 /// NM_017450 /// NM_017451 /// XM_005256943 /// XM_005256944 /// XM_005256945 /// XM_005256948 /// XM_006721635 /// XM_006721636 /// XM_006721637 /// XM_006721638 /// XR_429867 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 209503_s_at AF035309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035309.1 /DEF=Homo sapiens clone 23598 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:2661070 /UG=Hs.79387 proteasome (prosome, macropain) 26S subunit, ATPase, 5 /FL=gb:AF035309.1 AF035309 proteasome (prosome, macropain) 26S subunit, ATPase, 5 PSMC5 5705 NM_001199163 /// NM_002805 /// XM_006721980 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043069 // negative regulation of programmed cell death // non-traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0090261 // positive regulation of inclusion body assembly // inferred from electronic annotation 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031595 // nuclear proteasome complex // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0016887 // ATPase activity // traceable author statement /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0031531 // thyrotropin-releasing hormone receptor binding // inferred from physical interaction 209504_s_at AF081583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081583.1 /DEF=Homo sapiens KPL1 (KPL1) mRNA, complete cds. /FEA=mRNA /GEN=KPL1 /PROD=KPL1 /DB_XREF=gi:6650282 /UG=Hs.8124 PH domain containing protein in retina 1 /FL=gb:NM_021200.1 gb:U89715.1 gb:AF081583.1 AF081583 pleckstrin homology domain containing, family B (evectins) member 1 PLEKHB1 58473 NM_001130033 /// NM_001130034 /// NM_001130035 /// NM_001130036 /// NM_021200 /// XM_006718641 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007602 // phototransduction // non-traceable author statement /// 0045595 // regulation of cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 209505_at AI951185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI951185 /FEA=EST /DB_XREF=gi:5743495 /DB_XREF=est:wx64e12.x1 /CLONE=IMAGE:2548462 /UG=Hs.144630 nuclear receptor subfamily 2, group F, member 1 /FL=gb:BC004154.1 gb:NM_005654.1 AI951185 nuclear receptor subfamily 2, group F, member 1 NR2F1 7025 NM_005654 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209506_s_at BC004154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004154.1 /DEF=Homo sapiens, nuclear receptor subfamily 2, group F, member 1, clone MGC:2388, mRNA, complete cds. /FEA=mRNA /PROD=nuclear receptor subfamily 2, group F, member 1 /DB_XREF=gi:13278758 /UG=Hs.144630 nuclear receptor subfamily 2, group F, member 1 /FL=gb:BC004154.1 gb:NM_005654.1 BC004154 nuclear receptor subfamily 2, group F, member 1 /// nuclear receptor subfamily 2, group F, member 2 NR2F1 /// NR2F2 7025 /// 7026 NM_001145155 /// NM_001145156 /// NM_001145157 /// NM_005654 /// NM_021005 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009956 // radial pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209507_at BC005264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005264.1 /DEF=Homo sapiens, replication protein A3 (14kD), clone MGC:12305, mRNA, complete cds. /FEA=mRNA /PROD=replication protein A3 (14kD) /DB_XREF=gi:13528944 /UG=Hs.1608 replication protein A3 (14kD) /FL=gb:BC005264.1 gb:L07493.1 gb:NM_002947.1 BC005264 replication protein A3, 14kDa RPA3 6119 NM_002947 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209508_x_at AF005774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005774.1 /DEF=Homo sapiens caspase-like apoptosis regulatory protein (clarp) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=clarp /PROD=caspase-like apoptosis regulatory protein /DB_XREF=gi:2286144 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:BC001602.1 gb:U97074.1 gb:AF010127.1 gb:AF005774.1 gb:AF009618.1 gb:U85059.1 gb:AF041458.1 gb:AF041460.1 AF005774 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 209509_s_at BC000325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000325.1 /DEF=Homo sapiens, clone MGC:8482, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:8482) /DB_XREF=gi:12653116 /UG=Hs.26433 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) /FL=gb:BC000325.1 gb:NM_001382.1 BC000325 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) DPAGT1 1798 NM_001382 /// NM_203316 /// XM_005271422 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from mutant phenotype /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019348 // dolichol metabolic process // inferred from electronic annotation /// 0019408 // dolichol biosynthetic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003975 // UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity // inferred from direct assay /// 0003975 // UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity // inferred from mutant phenotype /// 0008963 // phospho-N-acetylmuramoyl-pentapeptide-transferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 209510_at AF064801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064801.1 /DEF=Homo sapiens multiple membrane spanning receptor TRC8 (TRC8) mRNA, complete cds. /FEA=mRNA /GEN=TRC8 /PROD=multiple membrane spanning receptor TRC8 /DB_XREF=gi:3395786 /UG=Hs.28285 patched related protein translocated in renal cancer /FL=gb:AF064801.1 gb:NM_007218.1 AF064801 ring finger protein 139 RNF139 11236 NM_007218 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0070613 // regulation of protein processing // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // traceable author statement /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209511_at BC003582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003582.1 /DEF=Homo sapiens, polymerase (RNA) II (DNA directed) polypeptide F, clone MGC:2669, mRNA, complete cds. /FEA=mRNA /PROD=polymerase (RNA) II (DNA directed) polypeptideF /DB_XREF=gi:13097770 /UG=Hs.46405 polymerase (RNA) II (DNA directed) polypeptide F /FL=gb:NM_021974.1 gb:BC003582.1 BC003582 polymerase (RNA) II (DNA directed) polypeptide F POLR2F 5435 NM_021974 /// XM_005261649 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation 209512_at BC004331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004331.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 2610207I16 gene, clone MGC:10940, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 2610207I16 gene /DB_XREF=gi:13279253 /UG=Hs.47986 Homo sapiens, Similar to RIKEN cDNA 2610207I16 gene, clone MGC:10940, mRNA, complete cds /FL=gb:BC004331.1 BC004331 hydroxysteroid dehydrogenase like 2 HSDL2 84263 NM_001195822 /// NM_032303 /// NR_036651 /// XM_006717303 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation 209513_s_at BC004331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004331.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 2610207I16 gene, clone MGC:10940, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 2610207I16 gene /DB_XREF=gi:13279253 /UG=Hs.47986 Homo sapiens, Similar to RIKEN cDNA 2610207I16 gene, clone MGC:10940, mRNA, complete cds /FL=gb:BC004331.1 BC004331 hydroxysteroid dehydrogenase like 2 HSDL2 84263 NM_001195822 /// NM_032303 /// NR_036651 /// XM_006717303 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation 209514_s_at BE502030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE502030 /FEA=EST /DB_XREF=gi:9704438 /DB_XREF=est:hy11d05.x1 /CLONE=IMAGE:3197001 /UG=Hs.50477 RAB27A, member RAS oncogene family /FL=gb:U38654.3 BE502030 RAB27A, member RAS oncogene family RAB27A 5873 NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation 209515_s_at U38654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38654.3 /DEF=Homo sapiens Rab27a mRNA, complete cds. /FEA=mRNA /PROD=Rab27a /DB_XREF=gi:4887230 /UG=Hs.50477 RAB27A, member RAS oncogene family /FL=gb:U38654.3 U38654 RAB27A, member RAS oncogene family RAB27A 5873 NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation 209516_at U50383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U50383.1 /DEF=Human retinoic acid-responsive protein (NN8-4AG) mRNA, complete cds. /FEA=mRNA /GEN=NN8-4AG /PROD=NN8-4AG /DB_XREF=gi:1245371 /UG=Hs.54413 retinoic acid responsive /FL=gb:U50383.1 U50383 SMYD family member 5 SMYD5 10322 NM_006062 /// XM_005264082 /// XM_006711917 /// XM_006711918 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209517_s_at AB020982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020982.1 /DEF=Homo sapiens ASH2L mRNA, complete cds, similar to Drosophila ash2 sequence. /FEA=mRNA /GEN=ASH2L /DB_XREF=gi:4417209 /UG=Hs.6856 ash2 (absent, small, or homeotic, Drosophila, homolog)-like /FL=gb:AF056718.1 gb:AB020982.1 gb:NM_004674.1 AB020982 ash2 (absent, small, or homeotic)-like (Drosophila) ASH2L 9070 NM_001105214 /// NM_001261832 /// NM_001282272 /// NM_004674 /// XM_005273682 /// XM_005273683 /// XM_006716412 /// XM_006716413 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from physical interaction /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from electronic annotation 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209518_at AI869240 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI869240 /FEA=EST /DB_XREF=gi:5543208 /DB_XREF=est:wl51d03.x1 /CLONE=IMAGE:2428421 /UG=Hs.79335 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 /FL=gb:AF109733.1 AI869240 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 SMARCD1 6602 NM_003076 /// NM_139071 /// XM_005269107 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 209519_at BG108193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG108193 /FEA=EST /DB_XREF=gi:12601959 /DB_XREF=est:602280062F1 /CLONE=IMAGE:4367751 /UG=Hs.89563 nuclear cap binding protein subunit 1, 80kD /FL=gb:BC001450.1 gb:D32002.1 gb:NM_002486.1 BG108193 nuclear cap binding protein subunit 1, 80kDa NCBP1 4686 NM_002486 /// XM_005251997 /// XM_006717118 /// XM_006717119 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from direct assay /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000339 // RNA cap binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209520_s_at BC001450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001450.1 /DEF=Homo sapiens, nuclear cap binding protein subunit 1, 80kD, clone MGC:2087, mRNA, complete cds. /FEA=mRNA /PROD=nuclear cap binding protein subunit 1, 80kD /DB_XREF=gi:12655186 /UG=Hs.89563 nuclear cap binding protein subunit 1, 80kD /FL=gb:BC001450.1 gb:D32002.1 gb:NM_002486.1 BC001450 nuclear cap binding protein subunit 1, 80kDa NCBP1 4686 NM_002486 /// XM_005251997 /// XM_006717118 /// XM_006717119 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from direct assay /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000339 // RNA cap binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209521_s_at AF286598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF286598.1 /DEF=Homo sapiens angiomotin mRNA, complete cds. /FEA=mRNA /PROD=angiomotin /DB_XREF=gi:9887325 /UG=Hs.9271 KIAA1071 protein /FL=gb:AF286598.1 AF286598 angiomotin AMOT 154796 NM_001113490 /// NM_133265 /// XM_005262087 /// XM_005262088 /// XM_005262089 /// XM_005262090 /// XM_006724623 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0003365 // establishment of cell polarity involved in ameboidal cell migration // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from direct assay /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0035329 // hippo signaling // inferred from genetic interaction /// 0035329 // hippo signaling // traceable author statement /// 0040019 // positive regulation of embryonic development // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045793 // positive regulation of cell size // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // traceable author statement 0001725 // stress fiber // inferred from direct assay /// 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043532 // angiostatin binding // inferred from direct assay 209522_s_at BC000723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000723.1 /DEF=Homo sapiens, Similar to carnitine acetyltransferase, clone MGC:1564, mRNA, complete cds. /FEA=mRNA /PROD=Similar to carnitine acetyltransferase /DB_XREF=gi:13111704 /UG=Hs.12068 carnitine acetyltransferase /FL=gb:BC000723.1 BC000723 carnitine O-acetyltransferase CRAT 1384 NM_000755 /// NM_001257363 /// NM_004003 /// NM_144782 /// XM_005251706 /// XM_005251707 /// XM_005251708 /// XM_005251709 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004092 // carnitine O-acetyltransferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 209523_at AK001618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001618.1 /DEF=Homo sapiens cDNA FLJ10756 fis, clone NT2RP3004572, highly similar to Homo sapiens cofactor of initiator function mRNA. /FEA=mRNA /DB_XREF=gi:7022983 /UG=Hs.122752 TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD /FL=gb:AF026445.1 gb:AF040701.1 gb:AF057694.1 gb:NM_003184.1 AK001618 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa TAF2 6873 NM_003184 /// XM_006716621 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 209524_at AK001280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001280.1 /DEF=Homo sapiens cDNA FLJ10418 fis, clone NT2RP1000130, moderately similar to HEPATOMA-DERIVED GROWTH FACTOR. /FEA=mRNA /DB_XREF=gi:7022435 /UG=Hs.127842 CGI-142 /FL=gb:AF151900.1 gb:AB029156.1 gb:NM_016073.1 AK001280 hepatoma-derived growth factor, related protein 3 HDGFRP3 50810 NM_016073 /// XM_006720554 0008283 // cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 209525_at BG285017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG285017 /FEA=EST /DB_XREF=gi:13036553 /DB_XREF=est:602409285F1 /CLONE=IMAGE:4538229 /UG=Hs.127842 CGI-142 /FL=gb:AF151900.1 gb:AB029156.1 gb:NM_016073.1 BG285017 hepatoma-derived growth factor, related protein 3 HDGFRP3 50810 NM_016073 /// XM_006720554 0008283 // cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 209526_s_at AB029156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB029156.1 /DEF=Homo sapiens HRP-3 mRNA, complete cds. /FEA=mRNA /GEN=HRP-3 /PROD=HRP-3 /DB_XREF=gi:6855467 /UG=Hs.127842 CGI-142 /FL=gb:AF151900.1 gb:AB029156.1 gb:NM_016073.1 AB029156 hepatoma-derived growth factor, related protein 3 HDGFRP3 50810 NM_016073 /// XM_006720554 0008283 // cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 209527_at BC000747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000747.1 /DEF=Homo sapiens, Similar to homolog of Yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease, clone MGC:2403, mRNA, complete cds. /FEA=mRNA /PROD=Similar to homolog of Yeast RRP4 (ribosomal RNAprocessing 4), 3-5-exoribonuclease /DB_XREF=gi:12653908 /UG=Hs.211973 homolog of Yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease /FL=gb:BC000747.1 BC000747 exosome component 2 EXOSC2 23404 NM_001282708 /// NM_001282709 /// NM_014285 /// NR_104230 /// XM_005272176 /// XM_006717020 /// XM_006717021 /// XM_006717022 /// XM_006717023 /// XM_006717024 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008312 // 7S RNA binding // traceable author statement 209528_s_at AL137394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL137394.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I062 (from clone DKFZp434I062); complete cds. /FEA=mRNA /GEN=DKFZp434I062 /PROD=hypothetical protein /DB_XREF=gi:6807928 /UG=Hs.226275 KIAA0683 gene product /FL=gb:AL080126.1 gb:AL137394.1 gb:NM_016111.1 AL137394 telomere maintenance 2 TELO2 9894 NM_016111 /// XM_006720993 /// XR_429650 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031931 // TORC1 complex // inferred from direct assay /// 0031932 // TORC2 complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation 209529_at AF047760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047760.1 /DEF=Homo sapiens phosphatidic acid phosphohydrolase type-2c mRNA, complete cds. /FEA=mRNA /PROD=phosphatidic acid phosphohydrolase type-2c /DB_XREF=gi:2911497 /UG=Hs.24879 phosphatidic acid phosphatase type 2C /FL=gb:BC002806.1 gb:AF047760.1 gb:AF056083.1 gb:AF035959.1 gb:NM_003712.1 AF047760 phosphatidic acid phosphatase type 2C PPAP2C 8612 NM_003712 /// NM_177526 /// NM_177543 0006665 // sphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209530_at U07139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U07139.1 /DEF=Human voltage-gated calcium channel beta subunit mRNA, complete cds. /FEA=mRNA /PROD=voltage-gated calcium channel beta subunit /DB_XREF=gi:463890 /UG=Hs.250712 calcium channel, voltage-dependent, beta 3 subunit /FL=gb:NM_000725.1 gb:U07139.1 U07139 calcium channel, voltage-dependent, beta 3 subunit CACNB3 784 NM_000725 /// NM_001206915 /// NM_001206916 /// NM_001206917 /// XM_005269142 /// XM_006719590 /// XM_006719591 /// XM_006719592 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 209531_at BC001453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001453.1 /DEF=Homo sapiens, glutathione transferase zeta 1 (maleylacetoacetate isomerase), clone MGC:2029, mRNA, complete cds. /FEA=mRNA /PROD=glutathione transferase zeta 1(maleylacetoacetate isomerase) /DB_XREF=gi:12655190 /UG=Hs.26403 glutathione transferase zeta 1 (maleylacetoacetate isomerase) /FL=gb:BC001453.1 gb:U86529.1 gb:NM_001513.1 BC001453 glutathione S-transferase zeta 1 GSTZ1 2954 NM_001513 /// NM_145870 /// NM_145871 /// XM_005267559 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004364 // glutathione transferase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016034 // maleylacetoacetate isomerase activity // not recorded /// 0016034 // maleylacetoacetate isomerase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 209532_at AF083395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF083395.1 /DEF=Homo sapiens phospholipase A2-activating protein mRNA, complete cds. /FEA=CDS /PROD=phospholipase A2-activating protein /DB_XREF=gi:4106817 /UG=Hs.27182 phospholipase A2-activating protein /FL=gb:AF083395.1 gb:NM_004253.1 gb:AF145020.1 AF083395 phospholipase A2-activating protein PLAA 9373 NM_001031689 /// NM_004253 0006644 // phospholipid metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016005 // phospholipase A2 activator activity // inferred from electronic annotation 209533_s_at AF145020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF145020.1 /DEF=Homo sapiens phospholipase A2 activating protein (PLA2P) mRNA, complete cds. /FEA=mRNA /GEN=PLA2P /PROD=phospholipase A2 activating protein /DB_XREF=gi:5326865 /UG=Hs.27182 phospholipase A2-activating protein /FL=gb:AF083395.1 gb:NM_004253.1 gb:AF145020.1 AF145020 phospholipase A2-activating protein PLAA 9373 NM_001031689 /// NM_004253 0006644 // phospholipid metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016005 // phospholipase A2 activator activity // inferred from electronic annotation 209534_x_at BF222823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222823 /FEA=EST /DB_XREF=gi:11130000 /DB_XREF=est:7q23e12.x1 /CLONE=IMAGE:3699190 /UG=Hs.301946 lymphoid blast crisis oncogene /FL=gb:AF127481.1 BF222823 A kinase (PRKA) anchor protein 13 AKAP13 11214 NM_001270546 /// NM_006738 /// NM_007200 /// NM_144767 /// XM_005254839 /// XM_005254840 /// XM_005254841 /// XM_005254842 /// XM_005254843 /// XM_005254844 /// XM_005254845 /// XM_005254846 /// XM_005254847 /// XM_005254848 /// XM_005254849 /// XM_005254850 /// XM_005254851 /// XM_005254852 /// XM_005254853 /// XM_005254854 /// XM_005254855 /// XM_005254856 /// XM_006720376 /// XM_006720377 /// XM_006720378 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 209535_s_at AF127481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF127481.1 /DEF=Homo sapiens non-ocogenic Rho GTPase-specific GTP exchange factor (proto-LBC) mRNA, complete cds. /FEA=mRNA /GEN=proto-LBC /PROD=non-ocogenic Rho GTPase-specific GTP exchangefactor /DB_XREF=gi:5199315 /UG=Hs.301946 lymphoid blast crisis oncogene /FL=gb:AF127481.1 AF127481 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 209536_s_at AF320070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF320070.1 /DEF=Homo sapiens hepatocellular carcinoma-associated protein HCA10 mRNA, complete cds. /FEA=mRNA /PROD=hepatocellular carcinoma-associated proteinHCA10 /DB_XREF=gi:11386004 /UG=Hs.55058 EH-domain containing 4 /FL=gb:AF307137.1 gb:AF320070.1 gb:AF323924.1 AF320070 EH-domain containing 4 EHD4 30844 NM_139265 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209537_at AF000416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000416.1 /DEF=Homo sapiens EXT-like protein 2 (EXTL2) mRNA, complete cds. /FEA=mRNA /GEN=EXTL2 /PROD=EXT-like protein 2 /DB_XREF=gi:2895061 /UG=Hs.61152 exostoses (multiple)-like 2 /FL=gb:AB009284.1 gb:AF000416.1 AF000416 exostosin-like glycosyltransferase 2 EXTL2 2135 NM_001033025 /// NM_001261440 /// NM_001261441 /// NM_001261442 /// NM_001439 /// NR_048570 /// XM_005270621 /// XM_005270622 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0019276 // UDP-N-acetylgalactosamine metabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001888 // glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0035248 // alpha-1,4-N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209538_at U69645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U69645.1 /DEF=Human zinc finger protein mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein /DB_XREF=gi:1575614 /UG=Hs.78765 zinc finger protein 32 (KOX 30) /FL=gb:U69645.1 U69645 zinc finger protein 32 ZNF32 7580 NM_001005368 /// NM_006973 /// XM_005271822 /// XM_005271823 /// XM_005271824 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209539_at D25304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D25304.1 /DEF=Human mRNA for KIAA0006 gene, partial cds. /FEA=mRNA /GEN=KIAA0006 /DB_XREF=gi:435445 /UG=Hs.79307 RacCdc42 guanine exchange factor (GEF) 6 /FL=gb:D13631.1 D25304 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 ARHGEF6 9459 NM_004840 /// XM_005262499 /// XM_005262501 /// XM_006724791 0006915 // apoptotic process // non-traceable author statement /// 0007254 // JNK cascade // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005096 // GTPase activator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 209540_at AU144912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144912 /FEA=EST /DB_XREF=gi:11006433 /DB_XREF=est:AU144912 /CLONE=HEMBA1003364 /UG=Hs.85112 insulin-like growth factor 1 (somatomedin C) /FL=gb:NM_000618.1 gb:M29644.1 gb:M27544.1 gb:X00173.1 AU144912 insulin-like growth factor 1 (somatomedin C) IGF1 3479 NM_000618 /// NM_001111283 /// NM_001111284 /// NM_001111285 /// XM_005268835 0001501 // skeletal system development // traceable author statement /// 0001775 // cell activation // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009441 // glycolate metabolic process // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from direct assay /// 0014896 // muscle hypertrophy // inferred from mutant phenotype /// 0014904 // myotube cell development // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from direct assay /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from expression pattern /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060741 // prostate gland stromal morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0031093 // platelet alpha granule lumen // traceable author statement 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 209541_at AI972496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI972496 /FEA=EST /DB_XREF=gi:5769242 /DB_XREF=est:wr38c02.x1 /CLONE=IMAGE:2489954 /UG=Hs.85112 insulin-like growth factor 1 (somatomedin C) /FL=gb:NM_000618.1 gb:M29644.1 gb:M27544.1 gb:X00173.1 AI972496 insulin-like growth factor 1 (somatomedin C) IGF1 3479 NM_000618 /// NM_001111283 /// NM_001111284 /// NM_001111285 /// XM_005268835 0001501 // skeletal system development // traceable author statement /// 0001775 // cell activation // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009441 // glycolate metabolic process // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from direct assay /// 0014896 // muscle hypertrophy // inferred from mutant phenotype /// 0014904 // myotube cell development // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from direct assay /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from expression pattern /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060741 // prostate gland stromal morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0031093 // platelet alpha granule lumen // traceable author statement 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 209542_x_at M29644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29644.1 /DEF=Human insulin-like growth factor I mRNA, complete cds. /FEA=mRNA /GEN=IGF1 /DB_XREF=gi:183119 /UG=Hs.85112 insulin-like growth factor 1 (somatomedin C) /FL=gb:NM_000618.1 gb:M29644.1 gb:M27544.1 gb:X00173.1 M29644 insulin-like growth factor 1 (somatomedin C) IGF1 3479 NM_000618 /// NM_001111283 /// NM_001111284 /// NM_001111285 /// XM_005268835 0001501 // skeletal system development // traceable author statement /// 0001775 // cell activation // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009441 // glycolate metabolic process // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from direct assay /// 0014896 // muscle hypertrophy // inferred from mutant phenotype /// 0014904 // myotube cell development // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from direct assay /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from expression pattern /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060741 // prostate gland stromal morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0031093 // platelet alpha granule lumen // traceable author statement 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 209543_s_at M81104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81104.1 /DEF=Human CD34 mRNA, complete cds. /FEA=mRNA /PROD=CD34 /DB_XREF=gi:180108 /UG=Hs.85289 CD34 antigen /FL=gb:M81104.1 M81104 CD34 molecule CD34 947 NM_001025109 /// NM_001773 0001894 // tissue homeostasis // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0003094 // glomerular filtration // inferred from expression pattern /// 0003158 // endothelium development // inferred from expression pattern /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from expression pattern /// 0008217 // regulation of blood pressure // inferred from direct assay /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from expression pattern /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035759 // mesangial cell-matrix adhesion // inferred from sequence or structural similarity /// 0038001 // paracrine signaling // inferred from direct assay /// 0042482 // positive regulation of odontogenesis // inferred from direct assay /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0048870 // cell motility // inferred from expression pattern /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from expression pattern /// 0060547 // negative regulation of necrotic cell death // inferred from direct assay /// 0061042 // vascular wound healing // inferred from expression pattern /// 0071425 // hematopoietic stem cell proliferation // inferred from mutant phenotype /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay /// 0071657 // positive regulation of granulocyte colony-stimulating factor production // inferred from direct assay /// 0071657 // positive regulation of granulocyte colony-stimulating factor production // inferred from expression pattern /// 0071971 // extracellular vesicular exosome assembly // inferred from direct assay /// 0072011 // glomerular endothelium development // inferred from expression pattern /// 0072089 // stem cell proliferation // inferred from expression pattern /// 0072254 // metanephric glomerular mesangial cell differentiation // inferred from expression pattern /// 1900035 // negative regulation of cellular response to heat // inferred from direct assay /// 1900038 // negative regulation of cellular response to hypoxia // inferred from direct assay /// 1900041 // negative regulation of interleukin-2 secretion // inferred from mutant phenotype /// 1900168 // positive regulation of glial cell line-derived neurotrophic factor secretion // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred by curator /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0036053 // glomerular endothelium fenestra // inferred from sequence or structural similarity /// 0045171 // intercellular bridge // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0008134 // transcription factor binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from direct assay /// 0043199 // sulfate binding // inferred from electronic annotation 209544_at AF027706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF027706.1 /DEF=Homo sapiens serinethreonine kinase RICK (RICK) mRNA, complete cds. /FEA=mRNA /GEN=RICK /PROD=serinethreonine kinase RICK /DB_XREF=gi:3123886 /UG=Hs.103755 receptor-interacting serine-threonine kinase 2 /FL=gb:BC004553.1 gb:AF027706.1 gb:AF064824.1 gb:AF078530.1 gb:NM_003821.1 AF027706 receptor-interacting serine-threonine kinase 2 RIPK2 8767 NM_003821 /// XM_005251092 0000187 // activation of MAPK activity // traceable author statement /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // non-traceable author statement /// 0032728 // positive regulation of interferon-beta production // non-traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // non-traceable author statement /// 0032743 // positive regulation of interleukin-2 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0033091 // positive regulation of immature T cell proliferation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070427 // nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0070671 // response to interleukin-12 // inferred from electronic annotation /// 0070673 // response to interleukin-18 // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071225 // cellular response to muramyl dipeptide // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030274 // LIM domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0050700 // CARD domain binding // inferred from direct assay /// 0050700 // CARD domain binding // inferred from physical interaction 209545_s_at AF064824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064824.1 /DEF=Homo sapiens CARD-containing ICE associated kinase mRNA, complete cds. /FEA=mRNA /PROD=CARD-containing ICE associated kinase /DB_XREF=gi:3290171 /UG=Hs.103755 receptor-interacting serine-threonine kinase 2 /FL=gb:BC004553.1 gb:AF027706.1 gb:AF064824.1 gb:AF078530.1 gb:NM_003821.1 AF064824 receptor-interacting serine-threonine kinase 2 RIPK2 8767 NM_003821 /// XM_005251092 0000187 // activation of MAPK activity // traceable author statement /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // non-traceable author statement /// 0032728 // positive regulation of interferon-beta production // non-traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // non-traceable author statement /// 0032743 // positive regulation of interleukin-2 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0033091 // positive regulation of immature T cell proliferation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070427 // nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0070671 // response to interleukin-12 // inferred from electronic annotation /// 0070673 // response to interleukin-18 // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071225 // cellular response to muramyl dipeptide // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030274 // LIM domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0050700 // CARD domain binding // inferred from direct assay /// 0050700 // CARD domain binding // inferred from physical interaction 209546_s_at AF323540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF323540.1 /DEF=Homo sapiens apolipoprotein L-I mRNA, splice variant B, complete cds. /FEA=mRNA /PROD=apolipoprotein L-I /DB_XREF=gi:12408012 /UG=Hs.114309 apolipoprotein L /FL=gb:NM_003661.1 gb:AF323540.1 AF323540 apolipoprotein L, 1 APOL1 8542 NM_001136540 /// NM_001136541 /// NM_003661 /// NM_145343 /// NM_145344 /// XM_005261795 /// XM_005261796 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019835 // cytolysis // inferred from direct assay /// 0031640 // killing of cells of other organism // inferred from direct assay /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031224 // intrinsic component of membrane // inferred by curator /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005254 // chloride channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 209547_s_at BC001043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001043.1 /DEF=Homo sapiens, clone MGC:1134, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1134) /DB_XREF=gi:12654434 /UG=Hs.15075 hypothetical protein DKFZp434E2216 /FL=gb:BC001043.1 gb:BC002986.1 BC001043 SURP and G patch domain containing 1 SUGP1 57794 NM_021164 /// NM_172231 /// NM_182812 /// XM_005260002 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209549_s_at BC001121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001121.1 /DEF=Homo sapiens, Similar to deoxyguanosine kinase, clone MGC:2111, mRNA, complete cds. /FEA=mRNA /PROD=Similar to deoxyguanosine kinase /DB_XREF=gi:12654572 /UG=Hs.326494 Homo sapiens, Similar to deoxyguanosine kinase, clone MGC:2111, mRNA, complete cds /FL=gb:BC001121.1 BC001121 deoxyguanosine kinase DGUOK 1716 NM_001929 /// NM_080915 /// NM_080916 /// NM_080917 /// NM_080918 /// XM_005264173 /// XM_005264174 /// XR_244926 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008617 // guanosine metabolic process // traceable author statement /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046070 // dGTP metabolic process // inferred from electronic annotation /// 0046122 // purine deoxyribonucleoside metabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004138 // deoxyguanosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded 209550_at U35139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35139.1 /DEF=Human NECDIN related protein mRNA, complete cds. /FEA=mRNA /PROD=NECDIN related protein /DB_XREF=gi:1754970 /UG=Hs.50130 necdin (mouse) homolog /FL=gb:NM_002487.2 gb:U35139.1 U35139 necdin, melanoma antigen (MAGE) family member NDN 4692 NM_002487 0001764 // neuron migration // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008347 // glial cell migration // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048871 // multicellular organismal homeostasis // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 209551_at BC004875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004875.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 2310034L04 gene, clone MGC:11061, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 2310034L04 gene /DB_XREF=gi:13436109 /UG=Hs.66309 Homo sapiens, Similar to RIKEN cDNA 2310034L04 gene, clone MGC:11061, mRNA, complete cds /FL=gb:BC004875.1 BC004875 Yip1 domain family, member 4 YIPF4 84272 NM_032312 /// XM_005264599 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 209552_at BC001060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001060.1 /DEF=Homo sapiens, paired box gene 8, clone MGC:2141, mRNA, complete cds. /FEA=mRNA /PROD=paired box gene 8 /DB_XREF=gi:12654464 /UG=Hs.73149 paired box gene 8 /FL=gb:BC001060.1 gb:L19606.1 gb:NM_003466.1 BC001060 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 209553_at BC001001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001001.2 /DEF=Homo sapiens, Similar to hBKLF for basic kruppel like factor, clone MGC:5362, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hBKLF for basic kruppel like factor /DB_XREF=gi:12803042 /UG=Hs.7316 KIAA0804 protein /FL=gb:BC001001.2 BC001001 vacuolar protein sorting 8 homolog (S. cerevisiae) VPS8 23355 NM_001009921 /// NM_015303 /// XM_005247251 /// XM_005247253 /// XM_006713556 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209554_at BE968792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE968792 /FEA=EST /DB_XREF=gi:10579497 /DB_XREF=est:601649985F1 /CLONE=IMAGE:3933789 /UG=Hs.75613 CD36 antigen (collagen type I receptor, thrombospondin receptor) /FL=gb:M98399.1 BE968792 CD36 molecule (thrombospondin receptor) CD36 948 NM_000072 /// NM_001001547 /// NM_001001548 /// NM_001127443 /// NM_001127444 /// NM_001289908 /// NM_001289909 /// NM_001289911 /// NR_110501 /// XM_005250713 /// XM_005250714 /// XM_005250715 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002221 // pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002576 // platelet degranulation // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010886 // positive regulation of cholesterol storage // inferred from electronic annotation /// 0015911 // plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0019915 // lipid storage // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042953 // lipoprotein transport // inferred from mutant phenotype /// 0042953 // lipoprotein transport // traceable author statement /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0055096 // low-density lipoprotein particle mediated signaling // inferred from electronic annotation /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0071221 // cellular response to bacterial lipopeptide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071447 // cellular response to hydroperoxide // inferred from electronic annotation /// 2000121 // regulation of removal of superoxide radicals // inferred from electronic annotation /// 2000334 // positive regulation of blood microparticle formation // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0045335 // phagocytic vesicle // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from mutant phenotype /// 0005041 // low-density lipoprotein receptor activity // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0070053 // thrombospondin receptor activity // inferred from sequence or structural similarity /// 0070892 // lipoteichoic acid receptor activity // inferred from electronic annotation /// 0071813 // lipoprotein particle binding // inferred from direct assay 209555_s_at M98399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M98399.1 /DEF=Human antigen CD36 (clone 21) mRNA, complete cds. /FEA=mRNA /GEN=CD36 /PROD=antigen CD36 /DB_XREF=gi:180112 /UG=Hs.75613 CD36 antigen (collagen type I receptor, thrombospondin receptor) /FL=gb:M98399.1 M98399 CD36 molecule (thrombospondin receptor) CD36 948 NM_000072 /// NM_001001547 /// NM_001001548 /// NM_001127443 /// NM_001127444 /// NM_001289908 /// NM_001289909 /// NM_001289911 /// NR_110501 /// XM_005250713 /// XM_005250714 /// XM_005250715 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002221 // pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002576 // platelet degranulation // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010886 // positive regulation of cholesterol storage // inferred from electronic annotation /// 0015911 // plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0019915 // lipid storage // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042953 // lipoprotein transport // inferred from mutant phenotype /// 0042953 // lipoprotein transport // traceable author statement /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0055096 // low-density lipoprotein particle mediated signaling // inferred from electronic annotation /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0071221 // cellular response to bacterial lipopeptide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071447 // cellular response to hydroperoxide // inferred from electronic annotation /// 2000121 // regulation of removal of superoxide radicals // inferred from electronic annotation /// 2000334 // positive regulation of blood microparticle formation // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0045335 // phagocytic vesicle // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from mutant phenotype /// 0005041 // low-density lipoprotein receptor activity // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0070053 // thrombospondin receptor activity // inferred from sequence or structural similarity /// 0070892 // lipoteichoic acid receptor activity // inferred from electronic annotation /// 0071813 // lipoprotein particle binding // inferred from direct assay 209556_at AB011179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011179.1 /DEF=Homo sapiens mRNA for KIAA0607 protein, partial cds. /FEA=mRNA /GEN=KIAA0607 /PROD=KIAA0607 protein /DB_XREF=gi:3043737 /UG=Hs.94653 neurochondrin /FL=gb:AB018740.2 AB011179 neurochondrin NCDN 23154 NM_001014839 /// NM_001014841 /// NM_014284 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0045453 // bone resorption // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 209557_s_at AB018740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB018740.2 /DEF=Homo sapiens mRNA for neurochondrin-2, complete cds. /FEA=mRNA /PROD=neurochondrin-2 /DB_XREF=gi:6136882 /UG=Hs.94653 neurochondrin /FL=gb:AB018740.2 AB018740 neurochondrin NCDN 23154 NM_001014839 /// NM_001014841 /// NM_014284 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0045453 // bone resorption // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 209558_s_at AB013384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013384.1 /DEF=Homo sapiens mRNA for HIP1R, complete cds. /FEA=mRNA /GEN=HIP1R /PROD=HIP1R /DB_XREF=gi:3721835 /UG=Hs.96731 huntingtin interacting protein-1-related /FL=gb:AB013384.1 AB013384 huntingtin interacting protein 1 related HIP1R 9026 NM_003959 /// XM_005253627 /// XM_005253628 /// XM_006719683 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 209559_at AB013384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013384.1 /DEF=Homo sapiens mRNA for HIP1R, complete cds. /FEA=mRNA /GEN=HIP1R /PROD=HIP1R /DB_XREF=gi:3721835 /UG=Hs.96731 huntingtin interacting protein-1-related /FL=gb:AB013384.1 AB013384 huntingtin interacting protein 1 related HIP1R 9026 NM_003959 /// XM_005253627 /// XM_005253628 /// XM_006719683 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 209560_s_at U15979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U15979.1 /DEF=Human (dlk) mRNA, complete cds. /FEA=mRNA /GEN=dlk /DB_XREF=gi:562105 /UG=Hs.169228 delta-like homolog (Drosophila) /FL=gb:NM_003836.1 gb:U15979.1 U15979 delta-like 1 homolog (Drosophila) DLK1 8788 NM_001032997 /// NM_003836 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 209561_at L38969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L38969.1 /DEF=Homo sapiens thrombospondin 3 (THBS3) mRNA, complete cds. /FEA=mRNA /GEN=THBS3 /PROD=thrombospondin 3 /DB_XREF=gi:886298 /UG=Hs.169875 thrombospondin 3 /FL=gb:NM_007112.1 gb:L38969.1 L38969 thrombospondin 3 THBS3 7059 NM_001252607 /// NM_001252608 /// NM_007112 /// NR_045553 /// XM_006711498 /// XM_006711499 /// XM_006711500 /// XM_006711501 /// XM_006711502 /// XR_426793 /// XR_426794 /// XR_426795 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0043931 // ossification involved in bone maturation // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay 209563_x_at BC000454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000454.1 /DEF=Homo sapiens, calmodulin 2 (phosphorylase kinase, delta), clone MGC:8460, mRNA, complete cds. /FEA=mRNA /PROD=calmodulin 2 (phosphorylase kinase, delta) /DB_XREF=gi:12653368 /UG=Hs.182278 calmodulin 2 (phosphorylase kinase, delta) /FL=gb:BC000454.1 BC000454 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 209565_at BC000832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000832.1 /DEF=Homo sapiens, zinc finger protein 183 (RING finger, C3HC4 type), clone MGC:4999, mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 183 (RING finger, C3HC4type) /DB_XREF=gi:12654052 /UG=Hs.64794 zinc finger protein 183 (RING finger, C3HC4 type) /FL=gb:BC000832.1 gb:NM_006978.1 BC000832 ring finger protein 113A RNF113A 7737 NM_006978 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209566_at AL080184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080184.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O071 (from clone DKFZp434O071). /FEA=mRNA /DB_XREF=gi:5262661 /UG=Hs.7089 insulin induced protein 2 /FL=gb:AF125392.1 AL080184 insulin induced gene 2 INSIG2 51141 NM_016133 /// XM_005263690 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0033993 // response to lipid // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation 209567_at BC001811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001811.1 /DEF=Homo sapiens, Similar to regulator for ribosome resistance homolog (S. cerevisiae), clone MGC:2755, mRNA, complete cds. /FEA=mRNA /PROD=Similar to regulator for ribosome resistancehomolog (S. cerevisiae) /DB_XREF=gi:12804750 /UG=Hs.71827 KIAA0112 protein; homolog of yeast ribosome biogenesis regulatory protein RRS1 /FL=gb:BC001811.1 BC001811 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) RRS1 23212 NM_015169 0007080 // mitotic metaphase plate congression // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209568_s_at AF186779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF186779.1 /DEF=Homo sapiens RGL protein (RGL) mRNA, complete cds. /FEA=mRNA /GEN=RGL /PROD=RGL protein /DB_XREF=gi:7682470 /UG=Hs.79219 RalGDS-like gene; KIAA0959 protein /FL=gb:AF186779.1 AF186779 ral guanine nucleotide dissociation stimulator-like 1 RGL1 23179 NM_015149 /// XM_005245010 /// XM_005245011 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0032315 // regulation of Ral GTPase activity // non-traceable author statement /// 0032852 // positive regulation of Ral GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0008321 // Ral guanyl-nucleotide exchange factor activity // non-traceable author statement 209569_x_at NM_014392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014392.1 /DEF=Homo sapiens neuron-specific protein (D4S234E), mRNA. /FEA=CDS /GEN=D4S234E /PROD=neuron-specific protein /DB_XREF=gi:7657002 /UG=Hs.79404 neuron-specific protein /FL=gb:BC001745.1 gb:NM_014392.1 NM_014392 neuron specific gene family member 1 NSG1 27065 NM_001040101 /// NM_001287763 /// NM_001287764 /// NM_014392 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0032051 // clathrin light chain binding // inferred from electronic annotation 209570_s_at BC001745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001745.1 /DEF=Homo sapiens, clone MGC:3328, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3328) /DB_XREF=gi:12804640 /UG=Hs.79404 neuron-specific protein /FL=gb:BC001745.1 gb:NM_014392.1 BC001745 neuron specific gene family member 1 NSG1 27065 NM_001040101 /// NM_001287763 /// NM_001287764 /// NM_014392 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0032051 // clathrin light chain binding // inferred from electronic annotation 209571_at U03644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03644.1 /DEF=Human recepin mRNA, complete cds. /FEA=mRNA /GEN=recepin /PROD=recepin /DB_XREF=gi:476104 /UG=Hs.89421 CBF1 interacting corepressor /FL=gb:AF098297.1 gb:NM_004882.1 gb:U03644.1 U03644 corepressor interacting with RBPJ, 1 CIR1 9541 NM_004882 /// NM_199075 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209572_s_at AF080227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080227.1 /DEF=Homo sapiens embryonic ectoderm development protein mRNA, complete cds. /FEA=mRNA /PROD=embryonic ectoderm development protein /DB_XREF=gi:3420789 /UG=Hs.151461 embryonic ectoderm development /FL=gb:AF080227.1 gb:U90651.1 gb:AF078933.1 AF080227 embryonic ectoderm development EED 8726 NM_003797 /// NM_152991 /// XM_005274373 /// XM_006718730 /// XM_006718731 /// XR_247215 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from electronic annotation 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 209573_s_at AW008505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW008505 /FEA=EST /DB_XREF=gi:5857283 /DB_XREF=est:wv68c10.x1 /CLONE=IMAGE:2534706 /UG=Hs.153498 chromosome 18 open reading frame 1 /FL=gb:AF009424.1 AW008505 low density lipoprotein receptor class A domain containing 4 LDLRAD4 753 NM_001003674 /// NM_001003675 /// NM_001276249 /// NM_001276251 /// NM_004338 /// NM_181481 /// NM_181482 /// NM_181483 /// XM_005258140 /// XM_006722350 /// XM_006722351 /// XM_006722352 /// XM_006722353 /// XM_006722354 /// XM_006722355 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 209574_s_at AI349506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI349506 /FEA=EST /DB_XREF=gi:4086712 /DB_XREF=est:qp71g08.x1 /CLONE=IMAGE:1928510 /UG=Hs.153498 chromosome 18 open reading frame 1 /FL=gb:AF009424.1 AI349506 low density lipoprotein receptor class A domain containing 4 LDLRAD4 753 NM_001003674 /// NM_001003675 /// NM_001276249 /// NM_001276251 /// NM_004338 /// NM_181481 /// NM_181482 /// NM_181483 /// XM_005258140 /// XM_006722350 /// XM_006722351 /// XM_006722352 /// XM_006722353 /// XM_006722354 /// XM_006722355 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 209575_at BC001903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001903.1 /DEF=Homo sapiens, Similar to interleukin 10 receptor, beta, clone MGC:2210, mRNA, complete cds. /FEA=mRNA /PROD=Similar to interleukin 10 receptor, beta /DB_XREF=gi:12804902 /UG=Hs.173936 interleukin 10 receptor, beta /FL=gb:BC001903.1 gb:NM_000628.1 BC001903 interleukin 10 receptor, beta IL10RB 3588 NM_000628 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032002 // interleukin-28 receptor complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004920 // interleukin-10 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209576_at AL049933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL049933.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K1216 (from clone DKFZp564K1216); complete cds. /FEA=mRNA /GEN=DKFZp564K1216 /PROD=hypothetical protein /DB_XREF=gi:4884070 /UG=Hs.203862 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 /FL=gb:AF055013.1 gb:AL049933.1 gb:NM_002069.1 AL049933 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 GNAI1 2770 NM_001256414 /// NM_002069 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from reviewed computational analysis /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209577_at BC000351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000351.1 /DEF=Homo sapiens, phosphate cytidylyltransferase 2, ethanolamine, clone MGC:8624, mRNA, complete cds. /FEA=mRNA /PROD=phosphate cytidylyltransferase 2, ethanolamine /DB_XREF=gi:12653166 /UG=Hs.226377 phosphate cytidylyltransferase 2, ethanolamine /FL=gb:BC000351.1 gb:D84307.1 gb:NM_002861.1 BC000351 phosphate cytidylyltransferase 2, ethanolamine PCYT2 5833 NM_001184917 /// NM_001256433 /// NM_001256434 /// NM_001256435 /// NM_001282203 /// NM_001282204 /// NM_002861 /// XM_005256386 /// XM_005256387 /// XM_006722287 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004306 // ethanolamine-phosphate cytidylyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 209578_s_at BC000626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000626.1 /DEF=Homo sapiens, clone MGC:3081, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3081) /DB_XREF=gi:12653682 /UG=Hs.22982 KIAA0958 protein /FL=gb:BC000626.1 BC000626 protein O-fucosyltransferase 2 POFUT2 23275 NM_015227 /// NM_133634 /// NM_133635 /// NR_004858 /// XM_006723981 /// XM_006723982 /// XM_006723983 /// XM_006723984 /// XR_430348 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036066 // protein O-linked fucosylation // inferred from direct assay /// 0051046 // regulation of secretion // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046922 // peptide-O-fucosyltransferase activity // inferred from direct assay 209579_s_at AL556619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL556619 /FEA=EST /DB_XREF=gi:12899460 /DB_XREF=est:AL556619 /CLONE=CS0DK006YH06 (5 prime) /UG=Hs.35947 methyl-CpG binding domain protein 4 /FL=gb:AF072250.1 gb:NM_003925.1 gb:AF114784.1 AL556619 methyl-CpG binding domain protein 4 MBD4 8930 NM_001276270 /// NM_001276271 /// NM_001276272 /// NM_001276273 /// NM_003925 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 209580_s_at AF114784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114784.1 /DEF=Homo sapiens methyl-CpG binding endonuclease (MED1) mRNA, complete cds. /FEA=mRNA /GEN=MED1 /PROD=methyl-CpG binding endonuclease /DB_XREF=gi:4539758 /UG=Hs.35947 methyl-CpG binding domain protein 4 /FL=gb:AF072250.1 gb:NM_003925.1 gb:AF114784.1 AF114784 methyl-CpG binding domain protein 4 MBD4 8930 NM_001276270 /// NM_001276271 /// NM_001276272 /// NM_001276273 /// NM_003925 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 209581_at BC001387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001387.1 /DEF=Homo sapiens, similar to rat HREV107, clone MGC:1240, mRNA, complete cds. /FEA=mRNA /PROD=similar to rat HREV107 /DB_XREF=gi:12655072 /UG=Hs.37189 similar to rat HREV107 /FL=gb:BC001387.1 gb:NM_007069.1 gb:AB030814.1 BC001387 phospholipase A2, group XVI PLA2G16 11145 NM_001128203 /// NM_007069 /// XM_006718426 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008970 // phosphatidylcholine 1-acylhydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0052739 // phosphatidylserine 1-acylhydrolase activity // inferred from electronic annotation /// 0052740 // 1-acyl-2-lysophosphatidylserine acylhydrolase activity // inferred from electronic annotation 209582_s_at H23979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H23979 /FEA=EST /DB_XREF=gi:892674 /DB_XREF=est:ym49a05.s1 /CLONE=IMAGE:51363 /UG=Hs.79015 antigen identified by monoclonal antibody MRC OX-2 /FL=gb:AF063591.1 H23979 CD200 molecule CD200 4345 NM_001004196 /// NM_001004197 /// NM_005944 /// XM_005247481 /// XM_005247482 /// XM_005247483 /// XM_005247484 /// XM_005247485 /// XM_005247486 /// XM_005247487 /// XM_005247488 /// XM_005247489 /// XM_005247490 /// XM_005247491 /// XM_006713648 /// XR_241493 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209583_s_at AF063591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF063591.1 /DEF=Homo sapiens brain my033 protein mRNA, complete cds. /FEA=mRNA /PROD=brain my033 protein /DB_XREF=gi:12002013 /UG=Hs.79015 antigen identified by monoclonal antibody MRC OX-2 /FL=gb:AF063591.1 AF063591 CD200 molecule CD200 4345 NM_001004196 /// NM_001004197 /// NM_005944 /// XM_005247481 /// XM_005247482 /// XM_005247483 /// XM_005247484 /// XM_005247485 /// XM_005247486 /// XM_005247487 /// XM_005247488 /// XM_005247489 /// XM_005247490 /// XM_005247491 /// XM_006713648 /// XR_241493 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209584_x_at AF165520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF165520.1 /DEF=Homo sapiens phorbolin I protein (PBI) mRNA, complete cds. /FEA=mRNA /GEN=PBI /PROD=phorbolin I protein /DB_XREF=gi:9294746 /UG=Hs.8583 similar to APOBEC1 /FL=gb:AF165520.1 AF165520 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C APOBEC3C 27350 NM_014508 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209585_s_at AF084943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF084943.1 /DEF=Homo sapiens multiple inositol polyphosphate phosphatase mRNA, complete cds. /FEA=mRNA /PROD=multiple inositol polyphosphate phosphatase /DB_XREF=gi:4191339 /UG=Hs.95907 multiple inositol polyphosphate phosphatase 1 /FL=gb:AF046914.1 gb:AF084943.1 gb:NM_004897.1 AF084943 multiple inositol-polyphosphate phosphatase 1 MINPP1 9562 NM_001178117 /// NM_001178118 /// NM_004897 /// XM_006718078 0001503 // ossification // non-traceable author statement /// 0006797 // polyphosphate metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0030282 // bone mineralization // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004446 // inositol-hexakisphosphate phosphatase activity // inferred from electronic annotation /// 0008969 // phosphohistidine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0034417 // bisphosphoglycerate 3-phosphatase activity // inferred from direct assay /// 0052826 // inositol hexakisphosphate 2-phosphatase activity // inferred from electronic annotation 209586_s_at AF123539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123539.1 /DEF=Homo sapiens clone 143 prune protein mRNA, complete cds., alternatively spliced. /FEA=mRNA /PROD=prune protein /DB_XREF=gi:12655791 /UG=Hs.78524 TcD37 homolog /FL=gb:AF123539.1 AF123539 prune exopolyphosphatase PRUNE 58497 NM_021222 /// XM_005245393 /// XM_005245394 /// XM_005245396 /// XM_005245397 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004427 // inorganic diphosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209587_at U70370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U70370.1 /DEF=Human hindlimb expressed homeobox protein backfoot (Bft) mRNA, complete cds. /FEA=mRNA /GEN=Bft /PROD=hindlimb expressed homeobox protein backfoot /DB_XREF=gi:1870670 /UG=Hs.84136 paired-like homeodomain transcription factor 1 /FL=gb:BC003685.1 gb:U70370.1 U70370 paired-like homeodomain 1 PITX1 5307 NM_002653 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014707 // branchiomeric skeletal muscle development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209588_at AL530874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL530874 /FEA=EST /DB_XREF=gi:12794367 /DB_XREF=est:AL530874 /CLONE=CS0DD003YJ13 (5 prime) /UG=Hs.125124 EphB2 /FL=gb:AF025304.1 AL530874 EPH receptor B2 EPHB2 2048 NM_004442 /// NM_017449 /// XM_006710441 /// XM_006710442 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007612 // learning // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209589_s_at AF025304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF025304.1 /DEF=Homo sapiens protein-tyrosine kinase EPHB2v (EPHB2) mRNA, complete cds. /FEA=mRNA /GEN=EPHB2 /PROD=protein-tyrosine kinase EPHB2v /DB_XREF=gi:2739055 /UG=Hs.125124 EphB2 /FL=gb:AF025304.1 AF025304 EPH receptor B2 EPHB2 2048 NM_004442 /// NM_017449 /// XM_006710441 /// XM_006710442 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007612 // learning // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209590_at AL157414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157414 /DEF=Human DNA sequence from clone RP11-560A15 on chromosome 20 Contains part of a novel gene, the 3 part of the BMP7 (bone morphogenetic protein 7 (osteogenic protein 1)) gene, ESTs, STSs, GSSs and a CpG island /FEA=mRNA_1 /DB_XREF=gi:9581576 /UG=Hs.170195 bone morphogenetic protein 7 (osteogenic protein 1) /FL=gb:M60316.1 gb:NM_001719.1 AL157414 bone morphogenetic protein 7 BMP7 655 NM_001719 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from expression pattern /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0016358 // dendrite development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity /// 0072040 // negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis // inferred from electronic annotation /// 0072125 // negative regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1900106 // positive regulation of hyaluranon cable assembly // inferred from direct assay /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 209591_s_at M60316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60316.1 /DEF=Human transforming growth factor-beta (tgf-beta) mRNA, complete cds. /FEA=mRNA /GEN=tgf-beta /PROD=transforming growth factor-beta /DB_XREF=gi:339563 /UG=Hs.170195 bone morphogenetic protein 7 (osteogenic protein 1) /FL=gb:M60316.1 gb:NM_001719.1 M60316 bone morphogenetic protein 7 BMP7 655 NM_001719 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from expression pattern /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0016358 // dendrite development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity /// 0072040 // negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis // inferred from electronic annotation /// 0072125 // negative regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1900106 // positive regulation of hyaluranon cable assembly // inferred from direct assay /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 209592_s_at BC001264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001264.1 /DEF=Homo sapiens, WD-repeat protein, clone MGC:5032, mRNA, complete cds. /FEA=mRNA /PROD=WD-repeat protein /DB_XREF=gi:12654840 /UG=Hs.176600 WD-repeat protein /FL=gb:BC001264.1 BC001264 DDB1 and CUL4 associated factor 7 DCAF7 10238 NM_001003725 /// NM_005828 /// NR_073585 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209593_s_at AF317129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF317129.1 /DEF=Homo sapiens FKSG18 (FKSG18) mRNA, complete cds. /FEA=mRNA /GEN=FKSG18 /PROD=FKSG18 /DB_XREF=gi:12276123 /UG=Hs.252682 torsin family 1, member B (torsin B) /FL=gb:AF317129.1 AF317129 torsin family 1, member B (torsin B) TOR1B 27348 NM_014506 /// XM_005251927 0006200 // ATP catabolic process // inferred from direct assay /// 0006986 // response to unfolded protein // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0071763 // nuclear membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 209594_x_at M34421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34421.1 /DEF=Human pregnancy-specific beta-1 glycoprotein mRNA, complete cds. /FEA=mRNA /GEN=PSG1 /DB_XREF=gi:183592 /UG=Hs.272620 pregnancy specific beta-1-glycoprotein 9 /FL=gb:M34421.1 gb:M58591.1 gb:M34481.1 M34421 pregnancy specific beta-1-glycoprotein 9 PSG9 5678 NM_002784 /// XM_005259074 /// XM_005259075 /// XM_005259076 /// XM_005259077 /// XM_005259078 /// XM_005259079 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 209595_at BC001771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001771.1 /DEF=Homo sapiens, general transcription factor IIF, polypeptide 2 (30kD subunit), clone MGC:1502, mRNA, complete cds. /FEA=mRNA /PROD=general transcription factor IIF, polypeptide 2(30kD subunit) /DB_XREF=gi:12804688 /UG=Hs.58593 general transcription factor IIF, polypeptide 2 (30kD subunit) /FL=gb:BC001771.1 gb:NM_004128.1 BC001771 general transcription factor IIF, polypeptide 2, 30kDa GTF2F2 2963 NM_004128 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209596_at AF245505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF245505.1 /DEF=Homo sapiens adlican mRNA, complete cds. /FEA=mRNA /PROD=adlican /DB_XREF=gi:9280404 /UG=Hs.72157 DKFZP564I1922 protein /FL=gb:AF245505.1 AF245505 matrix-remodelling associated 5 MXRA5 25878 NM_015419 /// XM_005274485 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 209597_s_at AF286487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF286487.1 /DEF=Homo sapiens paraneoplastic associated brain-testis-cancer antigen mRNA, complete cds. /FEA=mRNA /PROD=paraneoplastic associated brain-testis-cancerantigen /DB_XREF=gi:11055593 /UG=Hs.7782 paraneoplastic antigen MA2 /FL=gb:AF286487.1 gb:NM_007257.1 gb:AB020690.1 AF286487 paraneoplastic Ma antigen 2 PNMA2 10687 NM_007257 0006915 // apoptotic process // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209598_at AB020690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020690.1 /DEF=Homo sapiens mRNA for KIAA0883 protein, complete cds. /FEA=mRNA /GEN=KIAA0883 /PROD=KIAA0883 protein /DB_XREF=gi:4240254 /UG=Hs.7782 paraneoplastic antigen MA2 /FL=gb:AF286487.1 gb:NM_007257.1 gb:AB020690.1 AB020690 paraneoplastic Ma antigen 2 PNMA2 10687 NM_007257 0006915 // apoptotic process // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209599_s_at AI762105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762105 /FEA=EST /DB_XREF=gi:5177772 /DB_XREF=est:wi53g03.x1 /CLONE=IMAGE:2394004 /UG=Hs.78524 TcD37 homolog /FL=gb:AF123539.1 AI762105 prune exopolyphosphatase PRUNE 58497 NM_021222 /// XM_005245393 /// XM_005245394 /// XM_005245396 /// XM_005245397 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004427 // inorganic diphosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209600_s_at S69189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S69189.1 /DEF=Homo sapiens peroxisomal acyl-coenzyme A oxidase mRNA, complete cds. /FEA=mRNA /GEN=AOX /PROD=peroxisomal acyl-coenzyme A oxidase /DB_XREF=gi:545593 /UG=Hs.167835 acyl-Coenzyme A oxidase 1, palmitoyl /FL=gb:U07866.1 gb:S69189.1 S69189 acyl-CoA oxidase 1, palmitoyl ACOX1 51 NM_001185039 /// NM_004035 /// NM_007292 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from genetic interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2000189 // positive regulation of cholesterol homeostasis // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from direct assay /// 0003997 // acyl-CoA oxidase activity // inferred from genetic interaction /// 0003997 // acyl-CoA oxidase activity // inferred from mutant phenotype /// 0003997 // acyl-CoA oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0016401 // palmitoyl-CoA oxidase activity // inferred from direct assay /// 0016401 // palmitoyl-CoA oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 209601_at S69189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S69189.1 /DEF=Homo sapiens peroxisomal acyl-coenzyme A oxidase mRNA, complete cds. /FEA=mRNA /GEN=AOX /PROD=peroxisomal acyl-coenzyme A oxidase /DB_XREF=gi:545593 /UG=Hs.167835 acyl-Coenzyme A oxidase 1, palmitoyl /FL=gb:U07866.1 gb:S69189.1 S69189 acyl-CoA oxidase 1, palmitoyl ACOX1 51 NM_001185039 /// NM_004035 /// NM_007292 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from genetic interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2000189 // positive regulation of cholesterol homeostasis // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from direct assay /// 0003997 // acyl-CoA oxidase activity // inferred from genetic interaction /// 0003997 // acyl-CoA oxidase activity // inferred from mutant phenotype /// 0003997 // acyl-CoA oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0016401 // palmitoyl-CoA oxidase activity // inferred from direct assay /// 0016401 // palmitoyl-CoA oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 209602_s_at AI796169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796169 /FEA=EST /DB_XREF=gi:5361632 /DB_XREF=est:wh43d10.x1 /CLONE=IMAGE:2383507 /UG=Hs.169946 GATA-binding protein 3 /FL=gb:BC003070.1 gb:M69106.1 gb:NM_002051.1 AI796169 GATA binding protein 3 GATA3 2625 NM_001002295 /// NM_002051 /// XM_005252442 /// XM_005252443 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001806 // type IV hypersensitivity // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002572 // pro-T cell differentiation // inferred from electronic annotation /// 0003180 // aortic valve morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008584 // male gonad development // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from expression pattern /// 0035799 // ureter maturation // inferred from electronic annotation /// 0035898 // parathyroid hormone secretion // inferred from electronic annotation /// 0042035 // regulation of cytokine biosynthetic process // inferred from sequence or structural similarity /// 0042421 // norepinephrine biosynthetic process // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043370 // regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043583 // ear development // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from expression pattern /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from sequence or structural similarity /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060017 // parathyroid gland development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from direct assay /// 0060374 // mast cell differentiation // inferred from electronic annotation /// 0060676 // ureteric bud formation // inferred from sequence or structural similarity /// 0061085 // regulation of histone H3-K27 methylation // inferred from electronic annotation /// 0061290 // canonical Wnt signaling pathway involved in metanephric kidney development // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072107 // positive regulation of ureteric bud formation // inferred from sequence or structural similarity /// 0072178 // nephric duct morphogenesis // inferred from sequence or structural similarity /// 0072179 // nephric duct formation // inferred from sequence or structural similarity /// 0072182 // regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation /// 0072676 // lymphocyte migration // inferred from direct assay /// 2000114 // regulation of establishment of cell polarity // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2000607 // negative regulation of cell proliferation involved in mesonephros development // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000664 // positive regulation of interleukin-5 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from mutant phenotype /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from mutant phenotype /// 2000683 // regulation of cellular response to X-ray // inferred from mutant phenotype /// 2000703 // negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity /// 2000734 // negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from physical interaction 209603_at AI796169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796169 /FEA=EST /DB_XREF=gi:5361632 /DB_XREF=est:wh43d10.x1 /CLONE=IMAGE:2383507 /UG=Hs.169946 GATA-binding protein 3 /FL=gb:BC003070.1 gb:M69106.1 gb:NM_002051.1 AI796169 GATA binding protein 3 GATA3 2625 NM_001002295 /// NM_002051 /// XM_005252442 /// XM_005252443 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001806 // type IV hypersensitivity // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002572 // pro-T cell differentiation // inferred from electronic annotation /// 0003180 // aortic valve morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008584 // male gonad development // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from expression pattern /// 0035799 // ureter maturation // inferred from electronic annotation /// 0035898 // parathyroid hormone secretion // inferred from electronic annotation /// 0042035 // regulation of cytokine biosynthetic process // inferred from sequence or structural similarity /// 0042421 // norepinephrine biosynthetic process // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043370 // regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043583 // ear development // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from expression pattern /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from sequence or structural similarity /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060017 // parathyroid gland development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from direct assay /// 0060374 // mast cell differentiation // inferred from electronic annotation /// 0060676 // ureteric bud formation // inferred from sequence or structural similarity /// 0061085 // regulation of histone H3-K27 methylation // inferred from electronic annotation /// 0061290 // canonical Wnt signaling pathway involved in metanephric kidney development // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072107 // positive regulation of ureteric bud formation // inferred from sequence or structural similarity /// 0072178 // nephric duct morphogenesis // inferred from sequence or structural similarity /// 0072179 // nephric duct formation // inferred from sequence or structural similarity /// 0072182 // regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation /// 0072676 // lymphocyte migration // inferred from direct assay /// 2000114 // regulation of establishment of cell polarity // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2000607 // negative regulation of cell proliferation involved in mesonephros development // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000664 // positive regulation of interleukin-5 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from mutant phenotype /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from mutant phenotype /// 2000683 // regulation of cellular response to X-ray // inferred from mutant phenotype /// 2000703 // negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity /// 2000734 // negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from physical interaction 209604_s_at BC003070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003070.1 /DEF=Homo sapiens, GATA-binding protein 3, clone MGC:2346, mRNA, complete cds. /FEA=mRNA /PROD=GATA-binding protein 3 /DB_XREF=gi:13111765 /UG=Hs.169946 GATA-binding protein 3 /FL=gb:BC003070.1 gb:M69106.1 gb:NM_002051.1 BC003070 GATA binding protein 3 GATA3 2625 NM_001002295 /// NM_002051 /// XM_005252442 /// XM_005252443 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001806 // type IV hypersensitivity // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002572 // pro-T cell differentiation // inferred from electronic annotation /// 0003180 // aortic valve morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008584 // male gonad development // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from expression pattern /// 0035799 // ureter maturation // inferred from electronic annotation /// 0035898 // parathyroid hormone secretion // inferred from electronic annotation /// 0042035 // regulation of cytokine biosynthetic process // inferred from sequence or structural similarity /// 0042421 // norepinephrine biosynthetic process // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043370 // regulation of CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043583 // ear development // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from expression pattern /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0045064 // T-helper 2 cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from sequence or structural similarity /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060017 // parathyroid gland development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from direct assay /// 0060374 // mast cell differentiation // inferred from electronic annotation /// 0060676 // ureteric bud formation // inferred from sequence or structural similarity /// 0061085 // regulation of histone H3-K27 methylation // inferred from electronic annotation /// 0061290 // canonical Wnt signaling pathway involved in metanephric kidney development // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation /// 0072107 // positive regulation of ureteric bud formation // inferred from sequence or structural similarity /// 0072178 // nephric duct morphogenesis // inferred from sequence or structural similarity /// 0072179 // nephric duct formation // inferred from sequence or structural similarity /// 0072182 // regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation /// 0072676 // lymphocyte migration // inferred from direct assay /// 2000114 // regulation of establishment of cell polarity // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2000607 // negative regulation of cell proliferation involved in mesonephros development // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000664 // positive regulation of interleukin-5 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from direct assay /// 2000667 // positive regulation of interleukin-13 secretion // inferred from mutant phenotype /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from mutant phenotype /// 2000683 // regulation of cellular response to X-ray // inferred from mutant phenotype /// 2000703 // negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity /// 2000734 // negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from physical interaction 209605_at D87292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87292.1 /DEF=Homo sapiens mRNA for rhodanese, complete cds. /FEA=mRNA /PROD=rhodanese /DB_XREF=gi:1877030 /UG=Hs.248267 thiosulfate sulfurtransferase (rhodanese) /FL=gb:D87292.1 D87292 thiosulfate sulfurtransferase (rhodanese) TST 7263 NM_001270483 /// NM_003312 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009440 // cyanate catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035928 // rRNA import into mitochondrion // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051029 // rRNA transport // inferred from direct assay /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004792 // thiosulfate sulfurtransferase activity // inferred from electronic annotation /// 0008097 // 5S rRNA binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 209606_at L06633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L06633.1 /DEF=Human transcription factor mRNA, complete cds. /FEA=mRNA /PROD=transcription factor /DB_XREF=gi:431327 /UG=Hs.270 pleckstrin homology, Sec7 and coiledcoil domains, binding protein /FL=gb:AF068836.1 gb:L06633.1 gb:NM_004288.2 L06633 cytohesin 1 interacting protein CYTIP 9595 NM_004288 0030155 // regulation of cell adhesion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209607_x_at U08032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U08032.1 /DEF=Human thermolabile (monoamine, M form) phenol sulfotransferase (STM) mRNA, complete cds. /FEA=mRNA /GEN=STM /PROD=thermolabile (monoamine, M form) phenolsulfotransferase /DB_XREF=gi:468256 /UG=Hs.274614 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 /FL=gb:NM_003166.1 gb:L19956.1 gb:U34199.1 gb:U08032.1 U08032 sulfotransferase 1A3/1A4-like /// SLX1A-SULT1A3 readthrough (NMD candidate) /// SLX1B-SULT1A4 readthrough (NMD candidate) /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 LOC101929857 /// SLX1A-SULT1A3 /// SLX1B-SULT1A4 /// SULT1A3 /// SULT1A4 6818 /// 445329 /// 100526830 /// 100526831 /// 101929857 NM_001017387 /// NM_001017389 /// NM_001017390 /// NM_001017391 /// NM_003166 /// NM_177552 /// NR_037608 /// NR_037609 /// XM_005276506 /// XM_005276507 /// XM_006726621 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004062 // aryl sulfotransferase activity // traceable author statement /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 209608_s_at BC000408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000408.1 /DEF=Homo sapiens, acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase), clone MGC:8573, mRNA, complete cds. /FEA=mRNA /PROD=acetyl-Coenzyme A acetyltransferase 2(acetoacetyl Coenzyme A thiolase) /DB_XREF=gi:12653278 /UG=Hs.278544 acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) /FL=gb:BC000408.1 BC000408 acetyl-CoA acetyltransferase 2 ACAT2 39 NM_005891 /// XM_005266980 0006629 // lipid metabolic process // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003985 // acetyl-CoA C-acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 209609_s_at BC004517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004517.1 /DEF=Homo sapiens, Similar to RIKEN cDNA C330013D18 gene, clone MGC:11226, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA C330013D18 gene /DB_XREF=gi:13325435 /UG=Hs.288936 Homo sapiens, Similar to RIKEN cDNA C330013D18 gene, clone MGC:11226, mRNA, complete cds /FL=gb:BC004517.1 BC004517 mitochondrial ribosomal protein L9 MRPL9 65005 NM_031420 /// XM_005245455 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 209610_s_at BF340083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF340083 /FEA=EST /DB_XREF=gi:11286545 /DB_XREF=est:602037236F1 /CLONE=IMAGE:4185248 /UG=Hs.323878 solute carrier family 1 (glutamateneutral amino acid transporter), member 4 /FL=gb:L14595.1 gb:NM_003038.1 gb:L19444.1 gb:AB026689.1 BF340083 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 SLC1A4 6509 NM_001135581 /// NM_001193493 /// NM_003038 /// XM_006712079 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from direct assay /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // traceable author statement /// 0015808 // L-alanine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from direct assay /// 0015824 // proline transport // inferred from direct assay /// 0015825 // L-serine transport // inferred from direct assay /// 0015826 // threonine transport // inferred from direct assay /// 0034589 // hydroxyproline transport // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // non-traceable author statement /// 0035524 // proline transmembrane transport // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005254 // chloride channel activity // inferred from direct assay /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from direct assay /// 0015184 // L-cystine transmembrane transporter activity // inferred from direct assay /// 0015186 // L-glutamine transmembrane transporter activity // traceable author statement /// 0015193 // L-proline transmembrane transporter activity // inferred from direct assay /// 0015194 // L-serine transmembrane transporter activity // inferred from direct assay /// 0015195 // L-threonine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation /// 0034590 // L-hydroxyproline transmembrane transporter activity // inferred from direct assay 209611_s_at AB026689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026689.1 /DEF=Homo sapiens mRNA for hASCT1, complete cds. /FEA=mRNA /PROD=hASCT1 /DB_XREF=gi:7657952 /UG=Hs.323878 solute carrier family 1 (glutamateneutral amino acid transporter), member 4 /FL=gb:L14595.1 gb:NM_003038.1 gb:L19444.1 gb:AB026689.1 AB026689 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 SLC1A4 6509 NM_001135581 /// NM_001193493 /// NM_003038 /// XM_006712079 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from direct assay /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // traceable author statement /// 0015808 // L-alanine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from direct assay /// 0015824 // proline transport // inferred from direct assay /// 0015825 // L-serine transport // inferred from direct assay /// 0015826 // threonine transport // inferred from direct assay /// 0034589 // hydroxyproline transport // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // non-traceable author statement /// 0035524 // proline transmembrane transport // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005254 // chloride channel activity // inferred from direct assay /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from direct assay /// 0015184 // L-cystine transmembrane transporter activity // inferred from direct assay /// 0015186 // L-glutamine transmembrane transporter activity // traceable author statement /// 0015193 // L-proline transmembrane transporter activity // inferred from direct assay /// 0015194 // L-serine transmembrane transporter activity // inferred from direct assay /// 0015195 // L-threonine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation /// 0034590 // L-hydroxyproline transmembrane transporter activity // inferred from direct assay 209612_s_at M24317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24317.1 /DEF=Human class I alcohol dehydrogenase (ADH2) beta-1 subunit mRNA, complete cds. /FEA=mRNA /GEN=ADH2 /DB_XREF=gi:178097 /UG=Hs.4 alcohol dehydrogenase 2 (class I), beta polypeptide /FL=gb:NM_000668.2 gb:M24317.1 gb:M21692.1 gb:D00137.1 gb:AF153821.1 M24317 alcohol dehydrogenase 1B (class I), beta polypeptide ADH1B 125 NM_000668 /// NM_001286650 /// XM_006714079 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209613_s_at M21692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21692.1 /DEF=Human class I alcohol dehydrogenase (ADH2) beta-1 subunit mRNA, complete cds. /FEA=mRNA /GEN=ADH2 /DB_XREF=gi:178099 /UG=Hs.4 alcohol dehydrogenase 2 (class I), beta polypeptide /FL=gb:NM_000668.2 gb:M24317.1 gb:M21692.1 gb:D00137.1 gb:AF153821.1 M21692 alcohol dehydrogenase 1B (class I), beta polypeptide ADH1B 125 NM_000668 /// NM_001286650 /// XM_006714079 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209614_at AF153821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153821.1 /DEF=Homo sapiens alcohol dehydrogenase beta2 subunit mRNA, complete cds. /FEA=mRNA /PROD=alcohol dehydrogenase beta2 subunit /DB_XREF=gi:5002378 /UG=Hs.4 alcohol dehydrogenase 2 (class I), beta polypeptide /FL=gb:NM_000668.2 gb:M24317.1 gb:M21692.1 gb:D00137.1 gb:AF153821.1 AF153821 alcohol dehydrogenase 1B (class I), beta polypeptide ADH1B 125 NM_000668 /// NM_001286650 /// XM_006714079 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209615_s_at U51120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U51120.1 /DEF=Human protein kinase PAK1 mRNA, complete cds. /FEA=mRNA /PROD=PAK1 /DB_XREF=gi:1256421 /UG=Hs.62402 p21Cdc42Rac1-activated kinase 1 (yeast Ste20-related) /FL=gb:U51120.1 gb:NM_002576.2 gb:U24152.1 U51120 p21 protein (Cdc42/Rac)-activated kinase 1 PAK1 5058 NM_001128620 /// NM_002576 /// XM_005274025 /// XM_006718572 /// XM_006718573 /// XM_006718574 /// XM_006718575 /// XM_006718576 0000165 // MAPK cascade // inferred from direct assay /// 0000278 // mitotic cell cycle // not recorded /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006887 // exocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0031295 // T cell costimulation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042060 // wound healing // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0060244 // negative regulation of cell proliferation involved in contact inhibition // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from electronic annotation /// 0031941 // filamentous actin // non-traceable author statement /// 0031965 // nuclear membrane // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 209616_s_at S73751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S73751.1 /DEF=Homo sapiens acyl coenzyme A:cholesterol acyltransferase mRNA, complete cds. /FEA=mRNA /PROD=acyl coenzyme A:cholesterol acyltransferase /DB_XREF=gi:688112 /UG=Hs.76688 carboxylesterase 1 (monocytemacrophage serine esterase 1) /FL=gb:M73499.1 gb:L07764.1 gb:L07765.1 gb:AF177775.1 gb:S73751.1 gb:NM_001266.2 S73751 carboxylesterase 1 /// liver carboxylesterase 1-like CES1 /// LOC100653057 1066 /// 100653057 NM_001025194 /// NM_001025195 /// NM_001266 /// XM_005255774 /// XM_005276867 /// XM_006726229 0008152 // metabolic process // traceable author statement /// 0009636 // response to toxic substance // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // traceable author statement 209617_s_at AF035302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035302.1 /DEF=Homo sapiens clone 23717 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:2661061 /UG=Hs.80220 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) /FL=gb:NM_001332.1 gb:U72665.1 gb:AF035302.1 gb:U96136.1 gb:AB013805.1 AF035302 catenin (cadherin-associated protein), delta 2 CTNND2 1501 NM_001288715 /// NM_001288716 /// NM_001288717 /// NM_001332 /// NR_109988 /// XM_005248251 /// XM_005248252 /// XM_005248253 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007158 // neuron cell-cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209618_at U96136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96136.1 /DEF=Homo sapiens delta-catenin mRNA, complete cds. /FEA=mRNA /PROD=delta-catenin /DB_XREF=gi:3712672 /UG=Hs.80220 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) /FL=gb:NM_001332.1 gb:U72665.1 gb:AF035302.1 gb:U96136.1 gb:AB013805.1 U96136 catenin (cadherin-associated protein), delta 2 CTNND2 1501 NM_001288715 /// NM_001288716 /// NM_001288717 /// NM_001332 /// NR_109988 /// XM_005248251 /// XM_005248252 /// XM_005248253 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007158 // neuron cell-cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209619_at K01144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K01144.1 /DEF=Human major histocompatibility class II antigen gamma chain mRNA, complete cds. /FEA=mRNA /PROD=class II antigen gamma chain /DB_XREF=gi:188469 /UG=Hs.84298 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) /FL=gb:NM_004355.1 gb:K01144.1 K01144 CD74 molecule, major histocompatibility complex, class II invariant chain CD74 972 NM_001025158 /// NM_001025159 /// NM_004355 /// XM_006714811 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from electronic annotation /// 0002792 // negative regulation of peptide secretion // inferred from direct assay /// 0002830 // positive regulation of type 2 immune response // inferred from electronic annotation /// 0002906 // negative regulation of mature B cell apoptotic process // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006952 // defense response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0008283 // cell proliferation // inferred from direct assay /// 0016064 // immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019883 // antigen processing and presentation of endogenous antigen // non-traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0035691 // macrophage migration inhibitory factor signaling pathway // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045058 // T cell selection // non-traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045581 // negative regulation of T cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 2000343 // positive regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0035692 // macrophage migration inhibitory factor receptor complex // inferred from direct assay /// 0035693 // NOS2-CD74 complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004896 // cytokine receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0035718 // macrophage migration inhibitory factor binding // inferred from physical interaction /// 0042289 // MHC class II protein binding // inferred from sequence or structural similarity /// 0042289 // MHC class II protein binding // non-traceable author statement /// 0042658 // MHC class II protein binding, via antigen binding groove // inferred from direct assay /// 0042802 // identical protein binding // traceable author statement /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation 209620_s_at AB005289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB005289.1 /DEF=Homo sapiens mRNA for ABC transporter 7 protein, complete cds. /FEA=mRNA /GEN=hABC7 /PROD=ABC transporter 7 protein /DB_XREF=gi:3228278 /UG=Hs.125856 ATP-binding cassette, sub-family B (MDRTAP), member 7 /FL=gb:AB005289.1 gb:AF038950.1 gb:AF133659.1 gb:NM_004299.2 AB005289 ATP-binding cassette, sub-family B (MDR/TAP), member 7 ABCB7 22 NM_001271696 /// NM_001271697 /// NM_001271698 /// NM_001271699 /// NM_004299 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006879 // cellular iron ion homeostasis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0015886 // heme transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015232 // heme transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 209621_s_at AF002280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF002280.1 /DEF=Homo sapiens alpha-actinin-2 associated LIM protein mRNA, alternatively spliced product, complete cds. /FEA=mRNA /PROD=alpha-actinin-2 associated LIM protein /DB_XREF=gi:3138919 /UG=Hs.135281 alpha-actinin-2-associated LIM protein /FL=gb:AF039018.1 gb:AF002280.1 gb:NM_014476.1 AF002280 PDZ and LIM domain 3 PDLIM3 27295 NM_001114107 /// NM_001257962 /// NM_001257963 /// NM_014476 /// NR_047562 0007015 // actin filament organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209622_at AB020739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020739.1 /DEF=Homo sapiens mRNA for F5-2, complete cds. /FEA=mRNA /PROD=F5-2 /DB_XREF=gi:10640970 /UG=Hs.153003 serinethreonine kinase 16 /FL=gb:AB020739.1 gb:AF203910.1 gb:BC002618.1 gb:AF060798.1 gb:NM_003691.1 AB020739 serine/threonine kinase 16 STK16 8576 NM_001008910 /// NM_003691 /// NM_032768 /// NR_026909 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0002576 // platelet degranulation // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209623_at AW439494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW439494 /FEA=EST /DB_XREF=gi:6974800 /DB_XREF=est:xt19c01.x1 /CLONE=IMAGE:2779584 /UG=Hs.167531 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) /FL=gb:AB050049.1 gb:AF310971.1 gb:AF301000.1 gb:NM_022132.2 AW439494 methylcrotonoyl-CoA carboxylase 2 (beta) MCCC2 64087 NM_022132 /// XM_005248567 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004485 // methylcrotonoyl-CoA carboxylase activity // inferred from direct assay /// 0004485 // methylcrotonoyl-CoA carboxylase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 209624_s_at AB050049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB050049.1 /DEF=Homo sapiens mccb mRNA for non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase, complete cds. /FEA=mRNA /GEN=mccb /PROD=non-biotin containing subunit of3-methylcrotonyl-CoA carboxylase /DB_XREF=gi:10934058 /UG=Hs.167531 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) /FL=gb:AB050049.1 gb:AF310971.1 gb:AF301000.1 gb:NM_022132.2 AB050049 methylcrotonoyl-CoA carboxylase 2 (beta) MCCC2 64087 NM_022132 /// XM_005248567 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004485 // methylcrotonoyl-CoA carboxylase activity // inferred from direct assay /// 0004485 // methylcrotonoyl-CoA carboxylase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 209625_at BC004100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004100.1 /DEF=Homo sapiens, phosphatidylinositol glycan, class H, clone MGC:10360, mRNA, complete cds. /FEA=mRNA /PROD=phosphatidylinositol glycan, class H /DB_XREF=gi:13278629 /UG=Hs.177 phosphatidylinositol glycan, class H /FL=gb:BC004100.1 gb:L19783.1 gb:NM_004569.1 BC004100 phosphatidylinositol glycan anchor biosynthesis, class H PIGH 5283 NM_004569 /// XM_006720172 0006464 // cellular protein modification process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation 209626_s_at AI202969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI202969 /FEA=EST /DB_XREF=gi:3755575 /DB_XREF=est:qr32d06.x1 /CLONE=IMAGE:1942571 /UG=Hs.197955 KIAA0704 protein /FL=gb:AY008372.1 AI202969 oxysterol binding protein-like 3 OSBPL3 26031 NM_015550 /// NM_145320 /// NM_145321 /// NM_145322 /// NM_145323 /// NM_145324 /// NR_104111 /// NR_104112 /// XM_005249698 /// XM_006715681 /// XM_006715682 /// XM_006715683 /// XM_006715684 /// XR_428073 /// XR_428074 /// XR_428075 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 209627_s_at AY008372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY008372.1 /DEF=Homo sapiens oxysterol binding protein-related protein 3 (ORP3) mRNA, complete cds. /FEA=mRNA /GEN=ORP3 /PROD=oxysterol binding protein-related protein 3 /DB_XREF=gi:10880972 /UG=Hs.197955 KIAA0704 protein /FL=gb:AY008372.1 AY008372 oxysterol binding protein-like 3 OSBPL3 26031 NM_015550 /// NM_145320 /// NM_145321 /// NM_145322 /// NM_145323 /// NM_145324 /// NR_104111 /// NR_104112 /// XM_005249698 /// XM_006715681 /// XM_006715682 /// XM_006715683 /// XM_006715684 /// XR_428073 /// XR_428074 /// XR_428075 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 209628_at AK023289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023289.1 /DEF=Homo sapiens cDNA FLJ13227 fis, clone OVARC1000071, weakly similar to Homo sapiens NTF2-related export protein NXT1 (NXT1) mRNA. /FEA=mRNA /DB_XREF=gi:10435160 /UG=Hs.25010 hypothetical protein P15-2 /FL=gb:AF246127.1 gb:NM_018698.1 gb:AF201942.1 AK023289 nuclear transport factor 2-like export factor 2 NXT2 55916 NM_001242617 /// NM_001242618 /// NM_018698 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209629_s_at AF201942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201942.1 /DEF=Homo sapiens DC9 (DC9) mRNA, complete cds. /FEA=mRNA /GEN=DC9 /PROD=DC9 /DB_XREF=gi:9295187 /UG=Hs.25010 hypothetical protein P15-2 /FL=gb:AF246127.1 gb:NM_018698.1 gb:AF201942.1 AF201942 nuclear transport factor 2-like export factor 2 NXT2 55916 NM_001242617 /// NM_001242618 /// NM_018698 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209630_s_at AL043967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043967 /FEA=EST /DB_XREF=gi:5432195 /DB_XREF=est:DKFZp434H1028_s1 /CLONE=DKFZp434H1028 /UG=Hs.27747 G protein-coupled receptor 37 (endothelin receptor type B-like) /FL=gb:U87460.1 AL043967 F-box and WD repeat domain containing 2 FBXW2 26190 NM_012164 /// XM_005251908 /// XM_005251910 /// XM_005251912 /// XM_005251913 /// XM_006717049 /// XM_006717050 /// XM_006717051 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0016567 // protein ubiquitination // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209631_s_at U87460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87460.1 /DEF=Human putative endothelin receptor type B-like protein mRNA, complete cds. /FEA=mRNA /PROD=putative endothelin receptor type B-likeprotein /DB_XREF=gi:2076881 /UG=Hs.27747 G protein-coupled receptor 37 (endothelin receptor type B-like) /FL=gb:U87460.1 U87460 G protein-coupled receptor 37 (endothelin receptor type B-like) /// sel-1 suppressor of lin-12-like 2 (C. elegans) GPR37 /// SEL1L2 2861 /// 80343 NM_001271539 /// NM_005302 /// NM_025229 /// NR_073206 /// NR_073207 /// XM_006723646 /// XM_006723647 /// XM_006723648 /// XM_006723649 /// XM_006723650 /// XM_006723651 /// XM_006723652 /// XM_006723653 /// XM_006723654 /// XM_006723655 /// XM_006723656 /// XR_430270 /// XR_430271 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 209632_at AI760130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760130 /FEA=EST /DB_XREF=gi:5175797 /DB_XREF=est:wg58b07.x1 /CLONE=IMAGE:2369269 /UG=Hs.28219 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform /FL=gb:L07590.1 AI760130 protein phosphatase 2, regulatory subunit B'', alpha PPP2R3A 5523 NM_001190447 /// NM_002718 /// NM_181897 /// XM_006713686 0001754 // eye photoreceptor cell differentiation // inferred from genetic interaction /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007525 // somatic muscle development // inferred from genetic interaction /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 0061053 // somite development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred by curator /// 0090249 // regulation of cell motility involved in somitogenic axis elongation // inferred from genetic interaction /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209633_at AL389975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL389975.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 2004632. /FEA=mRNA /PROD=protein phosphatase 2A 72 kDa regulatorysubunit /DB_XREF=gi:9367827 /UG=Hs.28219 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform /FL=gb:L07590.1 AL389975 protein phosphatase 2, regulatory subunit B'', alpha PPP2R3A 5523 NM_001190447 /// NM_002718 /// NM_181897 /// XM_006713686 0001754 // eye photoreceptor cell differentiation // inferred from genetic interaction /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007525 // somatic muscle development // inferred from genetic interaction /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 0061053 // somite development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred by curator /// 0090249 // regulation of cell motility involved in somitogenic axis elongation // inferred from genetic interaction /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209635_at BC003561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003561.1 /DEF=Homo sapiens, Similar to adaptor-related protein complex 1, sigma 1 subunit, clone MGC:1929, mRNA, complete cds. /FEA=mRNA /PROD=Similar to adaptor-related protein complex 1,sigma 1 subunit /DB_XREF=gi:13097710 /UG=Hs.57600 adaptor-related protein complex 1, sigma 1 subunit /FL=gb:BC003561.1 BC003561 adaptor-related protein complex 1, sigma 1 subunit AP1S1 1174 NM_001283 /// NM_057089 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 209636_at BC002844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002844.1 /DEF=Homo sapiens, Similar to nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49p100, clone MGC:3685, mRNA, complete cds. /FEA=mRNA /PROD=Similar to nuclear factor of kappa lightpolypeptide gene enhancer in B-cells 2, p49p100 /DB_XREF=gi:12803988 /UG=Hs.73090 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49p100) /FL=gb:BC002844.1 BC002844 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) NFKB2 4791 NM_001077494 /// NM_001261403 /// NM_001288724 /// NM_002502 /// XM_005269860 /// XM_005269861 /// XM_006717869 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002268 // follicular dendritic cell differentiation // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048536 // spleen development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0033257 // Bcl3/NF-kappaB2 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209637_s_at AA887475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA887475 /FEA=EST /DB_XREF=gi:3003163 /DB_XREF=est:oj54a06.s1 /CLONE=IMAGE:1502098 /UG=Hs.78281 regulator of G-protein signalling 12 /FL=gb:AF030110.1 gb:AF030111.1 AA887475 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from direct assay 209638_x_at AF030110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF030110.1 /DEF=Homo sapiens regulator of G protein signaling RGS12 (RGS) mRNA, complete cds. /FEA=mRNA /GEN=RGS /PROD=regulator of G protein signaling RGS12 /DB_XREF=gi:2598195 /UG=Hs.78281 regulator of G-protein signalling 12 /FL=gb:AF030110.1 gb:AF030111.1 AF030110 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0030695 // GTPase regulator activity // inferred from direct assay 209639_s_at AF030111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF030111.1 /DEF=Homo sapiens regulator of G protein signaling RGS12 (RGS) mRNA, complete cds. /FEA=mRNA /GEN=RGS /PROD=regulator of G protein signaling /DB_XREF=gi:2599396 /UG=Hs.78281 regulator of G-protein signalling 12 /FL=gb:AF030110.1 gb:AF030111.1 AF030111 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from direct assay 209640_at M79462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M79462.1 /DEF=Human PML-1 mRNA, complete CDS. /FEA=mRNA /GEN=PML /DB_XREF=gi:190116 /UG=Hs.89633 promyelocytic leukemia /FL=gb:M79462.1 M79462 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 209641_s_at AF009670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009670.1 /DEF=Homo sapiens multidrug resistance-associated protein homolog MRP3 (MRP3) mRNA, complete cds. /FEA=mRNA /GEN=MRP3 /PROD=MRP3 /DB_XREF=gi:4102187 /UG=Hs.90786 ATP-binding cassette, sub-family C (CFTRMRP), member 3 /FL=gb:AB010887.1 gb:AF083552.1 gb:AF009670.1 gb:AF085690.1 gb:AF104943.1 gb:NM_003786.2 AF009670 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 ABCC3 8714 NM_001144070 /// NM_003786 /// NM_020037 /// NM_020038 /// XM_005257763 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 209642_at AF043294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043294.2 /DEF=Homo sapiens putative mitotic checkpoint kinase mRNA, complete cds. /FEA=mRNA /PROD=putative mitotic checkpoint kinase /DB_XREF=gi:6970210 /UG=Hs.98658 budding uninhibited by benzimidazoles 1 (yeast homolog) /FL=gb:AF047471.1 gb:AF053305.1 gb:AF046078.1 gb:NM_004336.1 gb:AF043294.2 AF043294 BUB1 mitotic checkpoint serine/threonine kinase BUB1 699 NM_001278616 /// NM_001278617 /// NM_004336 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007063 // regulation of sister chromatid cohesion // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype /// 0071173 // spindle assembly checkpoint // inferred from direct assay /// 0071173 // spindle assembly checkpoint // inferred from mutant phenotype /// 0071174 // mitotic spindle checkpoint // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209643_s_at AF033850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033850.1 /DEF=Homo sapiens phospholipase D2 (PLD2) mRNA, complete cds. /FEA=mRNA /GEN=PLD2 /PROD=phospholipase D2 /DB_XREF=gi:2645857 /UG=Hs.104519 phospholipase D2 /FL=gb:AF033850.1 gb:AF038440.1 gb:AF035483.1 gb:NM_002663.1 AF033850 phospholipase D2 PLD2 5338 NM_001243108 /// NM_002663 /// XM_005256695 /// XM_005256696 /// XM_005256697 /// XM_006721547 /// XM_006721548 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 209644_x_at U38945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38945.1 /DEF=Human hypothetical 18.1 kDa protein (CDKN2A) mRNA, complete cds. /FEA=mRNA /GEN=CDKN2A /DB_XREF=gi:1353569 /UG=Hs.1174 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) /FL=gb:U38945.1 gb:U26727.1 U38945 cyclin-dependent kinase inhibitor 2A CDKN2A 1029 NM_000077 /// NM_001195132 /// NM_058195 /// NM_058196 /// NM_058197 /// XM_005251343 0000075 // cell cycle checkpoint // inferred from mutant phenotype /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001953 // negative regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from mutant phenotype /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0031648 // protein destabilization // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from mutant phenotype /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from sequence or structural similarity /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0090398 // cellular senescence // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype /// 1902510 // regulation of apoptotic DNA fragmentation // inferred from mutant phenotype /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0055105 // ubiquitin-protein transferase inhibitor activity // inferred from sequence or structural similarity /// 0097371 // MDM2/MDM4 family protein binding // inferred from physical interaction 209645_s_at NM_000692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000692.1 /DEF=Homo sapiens aldehyde dehydrogenase 5 (ALDH5), mRNA. /FEA=CDS /GEN=ALDH5 /PROD=aldehyde dehydrogenase 5 /DB_XREF=gi:4502038 /UG=Hs.169517 aldehyde dehydrogenase 1 family, member B1 /FL=gb:BC001619.1 gb:NM_000692.1 NM_000692 aldehyde dehydrogenase 1 family, member B1 ALDH1B1 219 NM_000692 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 209646_x_at BC001619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001619.1 /DEF=Homo sapiens, Similar to aldehyde dehydrogenase 5, clone MGC:2230, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aldehyde dehydrogenase 5 /DB_XREF=gi:12804426 /UG=Hs.169517 aldehyde dehydrogenase 1 family, member B1 /FL=gb:BC001619.1 gb:NM_000692.1 BC001619 aldehyde dehydrogenase 1 family, member B1 ALDH1B1 219 NM_000692 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 209647_s_at AW664421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW664421 /FEA=EST /DB_XREF=gi:7456963 /DB_XREF=est:hi11g04.x1 /CLONE=IMAGE:2972022 /UG=Hs.169836 KIAA0671 gene product /FL=gb:AB014571.1 gb:AL136896.1 AW664421 suppressor of cytokine signaling 5 SOCS5 9655 NM_014011 /// NM_144949 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 209648_x_at AL136896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136896.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C198 (from clone DKFZp434C198); complete cds. /FEA=mRNA /GEN=DKFZp434C198 /PROD=hypothetical protein /DB_XREF=gi:6807674 /UG=Hs.169836 KIAA0671 gene product /FL=gb:AB014571.1 gb:AL136896.1 AL136896 suppressor of cytokine signaling 5 SOCS5 9655 NM_014011 /// NM_144949 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 209649_at AL133600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL133600.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C047 (from clone DKFZp564C047); complete cds. /FEA=mRNA /GEN=DKFZp564C047 /PROD=hypothetical protein /DB_XREF=gi:6599205 /UG=Hs.17200 STAM-like protein containing SH3 and ITAM domains 2 /FL=gb:AF042273.1 gb:AL133600.1 AL133600 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 STAM2 10254 NM_005843 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209650_s_at BC001292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001292.1 /DEF=Homo sapiens, chromosome 22 open reading frame 4, clone MGC:5258, mRNA, complete cds. /FEA=mRNA /PROD=chromosome 22 open reading frame 4 /DB_XREF=gi:12654894 /UG=Hs.20017 chromosome 22 open reading frame 4 /FL=gb:BC001292.1 BC001292 TBC1 domain family, member 22A TBC1D22A 25771 NM_001284303 /// NM_001284304 /// NM_001284305 /// NM_014346 /// NR_104292 /// XM_005261496 /// XM_006724223 /// XR_244364 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 209651_at BC001830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001830.1 /DEF=Homo sapiens, Similar to transforming growth factor beta 1 induced transcript 1, clone MGC:4078, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transforming growth factor beta 1induced transcript 1 /DB_XREF=gi:12804778 /UG=Hs.25511 transforming growth factor beta 1 induced transcript 1 /FL=gb:BC001830.1 gb:AF116343.1 gb:NM_015927.1 BC001830 transforming growth factor beta 1 induced transcript 1 TGFB1I1 7041 NM_001042454 /// NM_001164719 /// NM_015927 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction 209652_s_at BC001422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001422.1 /DEF=Homo sapiens, Similar to placental growth factor, vascular endothelial growth factor-related protein, clone MGC:1683, mRNA, complete cds. /FEA=mRNA /PROD=Similar to placental growth factor, vascularendothelial growth factor-related protein /DB_XREF=gi:12802997 /UG=Hs.2894 placental growth factor, vascular endothelial growth factor-related protein /FL=gb:BC001422.1 gb:S72960.1 BC001422 placental growth factor PGF 5228 NM_001207012 /// NM_001293643 /// NM_002632 /// XM_005267761 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060688 // regulation of morphogenesis of a branching structure // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from mutant phenotype /// 0008201 // heparin binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209653_at U93240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U93240.1 /DEF=Human importin alpha 3 mRNA, complete cds. /FEA=mRNA /PROD=importin alpha 3 /DB_XREF=gi:1928974 /UG=Hs.302499 karyopherin alpha 4 (importin alpha 3) /FL=gb:AB002533.2 gb:NM_002268.2 gb:U93240.1 U93240 karyopherin alpha 4 (importin alpha 3) KPNA4 3840 NM_002268 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 209654_at BC004902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004902.1 /DEF=Homo sapiens, clone MGC:4271, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4271) /DB_XREF=gi:13436178 /UG=Hs.5070 KIAA0947 protein /FL=gb:BC004902.1 BC004902 interactor of little elongator complex ELL subunit 1 ICE1 23379 NM_015325 0006869 // lipid transport // inferred from electronic annotation 0005319 // lipid transporter activity // inferred from electronic annotation 209655_s_at AI803181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803181 /FEA=EST /DB_XREF=gi:5368653 /DB_XREF=est:tc15a07.x1 /CLONE=IMAGE:2063892 /UG=Hs.8769 Homo sapiens mRNA; cDNA DKFZp761J17121 (from clone DKFZp761J17121); complete cds /FL=gb:AL136550.1 AI803181 transmembrane protein 47 TMEM47 83604 NM_031442 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 209656_s_at AL136550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136550.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761J17121 (from clone DKFZp761J17121); complete cds. /FEA=mRNA /GEN=DKFZp761J17121 /PROD=hypothetical protein /DB_XREF=gi:13276606 /UG=Hs.8769 Homo sapiens mRNA; cDNA DKFZp761J17121 (from clone DKFZp761J17121); complete cds /FL=gb:AL136550.1 AL136550 transmembrane protein 47 TMEM47 83604 NM_031442 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 209657_s_at M65217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M65217.1 /DEF=Human heat shock factor 2 (HSF2) mRNA, complete cds. /FEA=mRNA /GEN=heat shock factor 2 /PROD=HSF2 /DB_XREF=gi:184404 /UG=Hs.158195 heat shock transcription factor 2 /FL=gb:M65217.1 gb:NM_004506.2 M65217 heat shock transcription factor 2 HSF2 3298 NM_001135564 /// NM_001243094 /// NM_004506 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0001162 // RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209658_at AF164598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF164598.1 /DEF=Homo sapiens cell division control protein 16 (CDC16) mRNA, complete cds. /FEA=mRNA /GEN=CDC16 /PROD=cell division control protein 16 /DB_XREF=gi:5533374 /UG=Hs.1592 CDC16 (cell division cycle 16, S. cerevisiae, homolog) /FL=gb:AF164598.1 AF164598 cell division cycle 16 CDC16 8881 NM_001078645 /// NM_003903 /// XM_005266204 /// XM_005266206 /// XM_006719992 /// XM_006719993 /// XR_245358 /// XR_245359 /// XR_245360 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209659_s_at AF164598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF164598.1 /DEF=Homo sapiens cell division control protein 16 (CDC16) mRNA, complete cds. /FEA=mRNA /GEN=CDC16 /PROD=cell division control protein 16 /DB_XREF=gi:5533374 /UG=Hs.1592 CDC16 (cell division cycle 16, S. cerevisiae, homolog) /FL=gb:AF164598.1 AF164598 cell division cycle 16 CDC16 8881 NM_001078645 /// NM_003903 /// XM_005266204 /// XM_005266206 /// XM_006719992 /// XM_006719993 /// XR_245358 /// XR_245359 /// XR_245360 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209660_at AF162690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF162690.1 /DEF=Homo sapiens transthyretin precursor, mRNA, complete cds. /FEA=mRNA /PROD=transthyretin precursor /DB_XREF=gi:5533090 /UG=Hs.194366 transthyretin (prealbumin, amyloidosis type I) /FL=gb:BC005310.1 gb:K02091.1 gb:M10605.1 gb:D00096.1 gb:NM_000371.1 gb:AF162690.1 gb:U19780.1 AF162690 transthyretin TTR 7276 NM_000371 0001523 // retinoid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042562 // hormone binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209661_at BC001211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001211.1 /DEF=Homo sapiens, kinesin family member C3, clone MGC:3226, mRNA, complete cds. /FEA=mRNA /PROD=kinesin family member C3 /DB_XREF=gi:12654738 /UG=Hs.23131 kinesin family member C3 /FL=gb:BC001211.1 gb:AF004426.1 gb:NM_005550.1 BC001211 kinesin family member C3 KIFC3 3801 NM_001130099 /// NM_001130100 /// NM_005550 /// XM_005255937 /// XM_005255943 /// XM_005255944 /// XM_005255945 /// XM_005255946 /// XM_006721188 /// XM_006721189 /// XM_006721190 0007017 // microtubule-based process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0045218 // zonula adherens maintenance // inferred from mutant phenotype /// 0090136 // epithelial cell-cell adhesion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 209662_at BC005383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005383.1 /DEF=Homo sapiens, centrin, EF-hand protein, 3 (CDC31 yeast homolog), clone MGC:12502, mRNA, complete cds. /FEA=mRNA /PROD=centrin, EF-hand protein, 3 (CDC31 yeasthomolog) /DB_XREF=gi:13529247 /UG=Hs.29463 centrin, EF-hand protein, 3 (CDC31 yeast homolog) /FL=gb:BC005383.1 gb:NM_004365.1 BC005383 centrin, EF-hand protein, 3 CETN3 1070 NM_004365 /// XM_006714521 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209663_s_at AF072132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072132.1 /DEF=Homo sapiens integrin alpha-7 mRNA, complete cds. /FEA=mRNA /PROD=integrin alpha-7 /DB_XREF=gi:3930582 /UG=Hs.74369 integrin, alpha 7 /FL=gb:AF032108.1 gb:AF052050.1 gb:AF072132.1 gb:NM_002206.1 AF072132 integrin, alpha 7 ITGA7 3679 NM_001144996 /// NM_001144997 /// NM_002206 /// XM_005268839 /// XM_005268840 /// XM_005268841 /// XM_005268842 /// XM_005268844 /// XM_005268845 /// XM_005268846 /// XM_005268847 /// XM_005268848 /// XM_005268849 /// XM_005268850 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 209664_x_at AW027545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027545 /FEA=EST /DB_XREF=gi:5886301 /DB_XREF=est:wv74e05.x1 /CLONE=IMAGE:2535296 /UG=Hs.96149 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 /FL=gb:U80917.1 AW027545 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 4772 NM_001278669 /// NM_001278670 /// NM_001278672 /// NM_001278673 /// NM_001278675 /// NM_006162 /// NM_172387 /// NM_172388 /// NM_172389 /// NM_172390 /// XM_006722477 /// XM_006722478 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from sequence or structural similarity 209665_at AF040704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040704.1 /DEF=Homo sapiens putative tumor suppressor protein (101F6) mRNA, complete cds. /FEA=mRNA /GEN=101F6 /PROD=putative tumor suppressor protein /DB_XREF=gi:2935319 /UG=Hs.149443 putative tumor suppressor /FL=gb:AF040704.1 gb:NM_007022.1 AF040704 cytochrome b561 family, member D2 CYB561D2 11068 NM_001291284 /// NM_007022 /// NR_111912 /// NR_111913 /// NR_111914 /// XM_005264832 /// XR_245221 /// XR_245222 /// XR_245223 /// XR_249375 /// XR_251360 /// XR_251361 /// XR_251362 /// XR_425569 /// XR_425570 /// XR_425571 /// XR_427339 /// XR_427340 /// XR_431594 /// XR_431595 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 209666_s_at AF080157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080157.1 /DEF=Homo sapiens IkB kinase-a (IKK-alpha) mRNA, complete cds. /FEA=mRNA /GEN=IKK-alpha /PROD=IkB kinase-a /DB_XREF=gi:4185272 /UG=Hs.198998 conserved helix-loop-helix ubiquitous kinase /FL=gb:U22512.1 gb:AF012890.1 gb:AF009225.1 gb:AF080157.1 gb:NM_001278.1 AF080157 conserved helix-loop-helix ubiquitous kinase CHUK 1147 NM_001278 /// XR_246062 0001101 // response to acid // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007252 // I-kappaB phosphorylation // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from direct assay 209667_at BF033242 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF033242 /FEA=EST /DB_XREF=gi:10740954 /DB_XREF=est:601454201F1 /CLONE=IMAGE:3857928 /UG=Hs.282975 carboxylesterase 2 (intestine, liver) /FL=gb:U60553.1 gb:D50579.1 gb:NM_003869.2 BF033242 carboxylesterase 2 CES2 8824 NM_003869 /// NM_198061 /// NR_036684 0008152 // metabolic process // inferred from electronic annotation /// 0009056 // catabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // traceable author statement 209668_x_at D50579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50579.1 /DEF=Homo sapiens mRNA for carboxylesterase, complete cds. /FEA=mRNA /PROD=carboxylesterase precursor /DB_XREF=gi:2641989 /UG=Hs.282975 carboxylesterase 2 (intestine, liver) /FL=gb:U60553.1 gb:D50579.1 gb:NM_003869.2 D50579 carboxylesterase 2 CES2 8824 NM_003869 /// NM_198061 /// NR_036684 0008152 // metabolic process // inferred from electronic annotation /// 0009056 // catabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // traceable author statement 209669_s_at BC003049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003049.1 /DEF=Homo sapiens, Similar to DKFZP564M2423 protein, clone MGC:684, mRNA, complete cds. /FEA=mRNA /PROD=Similar to DKFZP564M2423 protein /DB_XREF=gi:12804376 /UG=Hs.324067 Homo sapiens, Similar to DKFZP564M2423 protein, clone MGC:684, mRNA, complete cds /FL=gb:BC003049.1 BC003049 SERPINE1 mRNA binding protein 1 SERBP1 26135 NM_001018067 /// NM_001018068 /// NM_001018069 /// NM_015640 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209670_at M12959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M12959.1 /DEF=Human T-cell receptor active alpha-chain mRNA from JM cell line, complete cds. /FEA=mRNA /GEN=TCRA /DB_XREF=gi:338734 /UG=Hs.74647 Human T-cell receptor active alpha-chain mRNA from JM cell line, complete cds /FL=gb:M12959.1 gb:M12423.1 M12959 T cell receptor alpha constant TRAC 28755 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209671_x_at M12423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M12423.1 /DEF=Human T-cell receptor active alpha-chain mRNA, complete cds, from Jurkat T-cell line. /FEA=mRNA /GEN=TCRA /DB_XREF=gi:338738 /UG=Hs.74647 Human T-cell receptor active alpha-chain mRNA from JM cell line, complete cds /FL=gb:M12959.1 gb:M12423.1 M12423 T cell receptor alpha constant TRAC 28755 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209672_s_at AL136892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136892.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434J087 (from clone DKFZp434J087); complete cds. /FEA=mRNA /GEN=DKFZp434J087 /PROD=hypothetical protein /DB_XREF=gi:12053282 /UG=Hs.83937 hypothetical protein /FL=gb:AL136892.1 AL136892 missing oocyte, meiosis regulator, homolog (Drosophila) MIOS 54468 NM_019005 /// XM_005249780 /// XM_005249781 /// XM_005249782 /// XM_005249783 /// XM_005249784 0005765 // lysosomal membrane // inferred from direct assay 209674_at D83702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83702.1 /DEF=Homo sapiens mRNA for photolyase, complete cds. /FEA=mRNA /PROD=photolyase /DB_XREF=gi:1304106 /UG=Hs.151573 cryptochrome 1 (photolyase-like) /FL=gb:D83702.1 gb:D84657.1 gb:NM_004075.1 D83702 cryptochrome circadian clock 1 CRY1 1407 NM_004075 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009785 // blue light signaling pathway // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 2000001 // regulation of DNA damage checkpoint // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from direct assay /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003904 // deoxyribodipyrimidine photo-lyase activity // inferred from direct assay /// 0003913 // DNA photolyase activity // inferred from electronic annotation /// 0003914 // DNA (6-4) photolyase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0009881 // photoreceptor activity // inferred from electronic annotation /// 0009882 // blue light photoreceptor activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity 209675_s_at BC004242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004242.1 /DEF=Homo sapiens, Similar to E1B-55kDa-associated protein 5, clone MGC:10422, mRNA, complete cds. /FEA=mRNA /PROD=Similar to E1B-55kDa-associated protein 5 /DB_XREF=gi:13278995 /UG=Hs.155218 E1B-55kDa-associated protein 5 /FL=gb:BC004242.1 BC004242 heterogeneous nuclear ribonucleoprotein U-like 1 HNRNPUL1 11100 NM_007040 /// NM_144732 /// NM_144733 /// NM_144734 /// XM_005258459 /// XM_005258461 /// XM_005258462 /// XM_005258463 /// XM_005258464 /// XM_005258465 /// XM_005258466 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209676_at J03225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03225.1 /DEF=Human lipoprotein-associated coagulation inhibitor mRNA, complete cds. /FEA=mRNA /GEN=TFPI /DB_XREF=gi:180545 /UG=Hs.170279 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) /FL=gb:J03225.1 gb:NM_006287.2 J03225 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 7035 NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 209677_at L18964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L18964.1 /DEF=Human protein kinase C iota isoform (PRKCI) mRNA, complete cds. /FEA=mRNA /GEN=PRKCI /PROD=protein kinase C iota /DB_XREF=gi:432273 /UG=Hs.1904 protein kinase C, iota /FL=gb:L18964.1 gb:NM_002740.1 gb:L33881.1 L18964 protein kinase C, iota PRKCI 5584 NM_002740 0006468 // protein phosphorylation // inferred from direct assay /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035089 // establishment of apical/basal cell polarity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046903 // secretion // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048194 // Golgi vesicle budding // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060252 // positive regulation of glial cell proliferation // inferred from mutant phenotype /// 0061024 // membrane organization // non-traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0000133 // polarisome // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209678_s_at L18964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L18964.1 /DEF=Human protein kinase C iota isoform (PRKCI) mRNA, complete cds. /FEA=mRNA /GEN=PRKCI /PROD=protein kinase C iota /DB_XREF=gi:432273 /UG=Hs.1904 protein kinase C, iota /FL=gb:L18964.1 gb:NM_002740.1 gb:L33881.1 L18964 protein kinase C, iota PRKCI 5584 NM_002740 0006468 // protein phosphorylation // inferred from direct assay /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035089 // establishment of apical/basal cell polarity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046903 // secretion // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048194 // Golgi vesicle budding // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060252 // positive regulation of glial cell proliferation // inferred from mutant phenotype /// 0061024 // membrane organization // non-traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0000133 // polarisome // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209679_s_at BC003379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003379.1 /DEF=Homo sapiens, hypothetical protein from clone 643, clone MGC:5115, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein from clone 643 /DB_XREF=gi:13097236 /UG=Hs.206501 hypothetical protein from clone 643 /FL=gb:BC003379.1 gb:NM_020467.1 BC003379 small cell adhesion glycoprotein SMAGP 57228 NM_001031628 /// NM_001033873 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 209680_s_at BC000712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000712.1 /DEF=Homo sapiens, Similar to kinesin family member C1, clone MGC:1202, mRNA, complete cds. /FEA=mRNA /PROD=Similar to kinesin family member C1 /DB_XREF=gi:12653842 /UG=Hs.20830 kinesin-like 2 /FL=gb:BC000712.1 BC000712 kinesin family member C1 KIFC1 3833 NM_002263 /// XM_005249092 /// XM_005275403 /// XM_005275553 /// XM_005275555 /// XM_006715094 /// XM_006726001 /// XM_006726094 0000070 // mitotic sister chromatid segregation // non-traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // non-traceable author statement /// 0008017 // microtubule binding // inferred from electronic annotation 209681_at AF153330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153330.1 /DEF=Homo sapiens thiamine carrier 1 (TC1) mRNA, complete cds. /FEA=mRNA /GEN=TC1 /PROD=thiamine carrier 1 /DB_XREF=gi:5453325 /UG=Hs.30246 solute carrier family 19 (thiamine transporter), member 2 /FL=gb:AF153330.1 gb:AF135488.1 gb:AF160812.1 AF153330 solute carrier family 19 (thiamine transporter), member 2 SLC19A2 10560 NM_006996 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015884 // folic acid transport // non-traceable author statement /// 0015888 // thiamine transport // non-traceable author statement /// 0042723 // thiamine-containing compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071934 // thiamine transmembrane transport // inferred from electronic annotation /// 0071934 // thiamine transmembrane transport // inferred from sequence or structural similarity /// 0071934 // thiamine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005542 // folic acid binding // inferred from electronic annotation /// 0008517 // folic acid transporter activity // non-traceable author statement /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015234 // thiamine transmembrane transporter activity // traceable author statement /// 0015403 // thiamine uptake transmembrane transporter activity // inferred from sequence or structural similarity 209682_at U26710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U26710.1 /DEF=Human cbl-b mRNA, complete cds. /FEA=mRNA /PROD=cbl-b /DB_XREF=gi:862406 /UG=Hs.3144 Cas-Br-M (murine) ectropic retroviral transforming sequence b /FL=gb:U26710.1 U26710 Cbl proto-oncogene B, E3 ubiquitin protein ligase CBLB 868 NM_170662 /// XM_005247852 /// XM_005247853 /// XM_006713796 /// XM_006713797 /// XR_427384 /// XR_427385 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0023051 // regulation of signaling // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209683_at AA243659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA243659 /FEA=EST /DB_XREF=gi:1874478 /DB_XREF=est:zr68c06.s1 /CLONE=IMAGE:668554 /UG=Hs.4863 hypothetical protein DKFZp566A1524 /FL=gb:AL136704.1 AA243659 family with sequence similarity 49, member A FAM49A 81553 NM_030797 /// XM_005262630 /// XM_006712108 0005622 // intracellular // inferred from direct assay 209684_at AL136924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136924.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586G2120 (from clone DKFZp586G2120); complete cds. /FEA=mRNA /GEN=DKFZp586G2120 /PROD=hypothetical protein /DB_XREF=gi:12053342 /UG=Hs.62349 ras association (RalGDSAF-6) domain containing protein JC265 /FL=gb:AL136924.1 AL136924 Ras and Rab interactor 2 RIN2 54453 NM_001242581 /// NM_018993 /// XM_005260730 /// XM_005260731 /// XM_005260732 /// XM_005260733 /// XM_006723573 /// XM_006723574 /// XM_006723575 /// XM_006723576 /// XM_006723577 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0032313 // regulation of Rab GTPase activity // non-traceable author statement /// 0032851 // positive regulation of Rab GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // non-traceable author statement 209685_s_at M13975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13975.1 /DEF=Homo sapiens protein kinase C beta-II type (PRKCB1) mRNA, complete cds. /FEA=mRNA /GEN=PRKCB1 /PROD=protein kinase C beta-II type /DB_XREF=gi:189968 /UG=Hs.77202 protein kinase C, beta 1 /FL=gb:M13975.1 M13975 protein kinase C, beta PRKCB 5579 NM_002738 /// NM_212535 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010829 // negative regulation of glucose transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042953 // lipoprotein transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050861 // positive regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay 209686_at BC001766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001766.1 /DEF=Homo sapiens, S100 calcium-binding protein, beta (neural), clone MGC:1323, mRNA, complete cds. /FEA=mRNA /PROD=S100 calcium-binding protein, beta (neural) /DB_XREF=gi:12804680 /UG=Hs.83384 S100 calcium-binding protein, beta (neural) /FL=gb:BC001766.1 gb:NM_006272.1 BC001766 S100 calcium binding protein B S100B 6285 NM_006272 0007409 // axonogenesis // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048708 // astrocyte differentiation // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2001015 // negative regulation of skeletal muscle cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from physical interaction 209687_at U19495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19495.1 /DEF=Human intercrine-alpha (hIRH) mRNA, complete cds. /FEA=mRNA /GEN=hIRH /PROD=intercrine-alpha /DB_XREF=gi:1754834 /UG=Hs.237356 stromal cell-derived factor 1 /FL=gb:L36034.1 gb:U19495.1 U19495 chemokine (C-X-C motif) ligand 12 CXCL12 6387 NM_000609 /// NM_001033886 /// NM_001178134 /// NM_001277990 /// NM_199168 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from mutant phenotype /// 0045236 // CXCR chemokine receptor binding // inferred from direct assay 209688_s_at BC005078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005078.1 /DEF=Homo sapiens, clone MGC:13033, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13033) /DB_XREF=gi:13477224 /UG=Hs.26118 Homo sapiens clone 24766 mRNA sequence /FL=gb:BC005078.1 BC005078 coiled-coil domain containing 93 CCDC93 54520 NM_019044 /// XM_006712597 /// XM_006712598 /// XM_006712599 /// XM_006712600 209689_at BC005078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005078.1 /DEF=Homo sapiens, clone MGC:13033, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13033) /DB_XREF=gi:13477224 /UG=Hs.26118 Homo sapiens clone 24766 mRNA sequence /FL=gb:BC005078.1 BC005078 coiled-coil domain containing 93 CCDC93 54520 NM_019044 /// XM_006712597 /// XM_006712598 /// XM_006712599 /// XM_006712600 209690_s_at BF591163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF591163 /FEA=EST /DB_XREF=gi:11683487 /DB_XREF=est:7h54g09.x1 /CLONE=IMAGE:3319840 /UG=Hs.279832 hypothetical protein FLJ10488 /FL=gb:BC003541.1 BF591163 docking protein 4 DOK4 55715 NM_018110 /// XM_005256042 /// XM_005256043 0000165 // MAPK cascade // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 209691_s_at BC003541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003541.1 /DEF=Homo sapiens, hypothetical protein FLJ10488, clone MGC:10806, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10488 /DB_XREF=gi:13097653 /UG=Hs.279832 hypothetical protein FLJ10488 /FL=gb:BC003541.1 BC003541 docking protein 4 DOK4 55715 NM_018110 /// XM_005256042 /// XM_005256043 0000165 // MAPK cascade // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 209692_at U71207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71207.1 /DEF=Human eyes absent homolog (Eab1) mRNA, complete cds. /FEA=mRNA /GEN=Eab1 /PROD=Eab1 /DB_XREF=gi:1916005 /UG=Hs.29279 eyes absent (Drosophila) homolog 2 /FL=gb:U71207.1 gb:NM_005244.1 U71207 EYA transcriptional coactivator and phosphatase 2 EYA2 2139 NM_005244 /// NM_172110 /// NM_172111 /// NM_172112 /// NM_172113 /// XM_005260327 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007501 // mesodermal cell fate specification // traceable author statement /// 0014706 // striated muscle tissue development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097345 // mitochondrial outer membrane permeabilization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209693_at AF116574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116574.1 /DEF=Homo sapiens astrotactin2 (ASTN2) mRNA, complete cds. /FEA=mRNA /GEN=ASTN2 /PROD=astrotactin2 /DB_XREF=gi:6502572 /UG=Hs.30898 KIAA0634 protein /FL=gb:AF116574.1 AF116574 astrotactin 2 ASTN2 23245 NM_001184734 /// NM_001184735 /// NM_014010 /// NM_198186 /// NM_198187 /// NM_198188 2000009 // negative regulation of protein localization to cell surface // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0060187 // cell pole // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209694_at M97655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M97655.1 /DEF=Human 6-pyruvoyltetrahydropterin synthase (PTS) mRNA, complete cds. /FEA=mRNA /GEN=PTS /PROD=6-pyruvoyltetrahydropterin synthase /DB_XREF=gi:306438 /UG=Hs.366 6-pyruvoyltetrahydropterin synthase /FL=gb:M97655.1 gb:NM_000317.1 gb:D17400.1 M97655 6-pyruvoyltetrahydropterin synthase PTS 5805 NM_000317 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003874 // 6-pyruvoyltetrahydropterin synthase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209695_at BC003105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003105.1 /DEF=Homo sapiens, Similar to protein tyrosine phosphatase type IVA, member 3, clone MGC:1950, mRNA, complete cds. /FEA=mRNA /PROD=Similar to protein tyrosine phosphatase typeIVA, member 3 /DB_XREF=gi:13111874 /UG=Hs.43666 protein tyrosine phosphatase type IVA, member 3 /FL=gb:BC003105.1 BC003105 protein tyrosine phosphatase type IVA, member 3 PTP4A3 11156 NM_007079 /// NM_032611 /// XM_005250762 /// XM_005250763 /// XM_005250764 /// XM_005250766 /// XM_005250767 /// XM_006716499 /// XM_006716500 /// XM_006725100 /// XM_006725101 /// XM_006725102 /// XM_006725103 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 209696_at D26054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D26054.1 /DEF=Human mRNA for fructose-1,6-bisphosphatase, complete cds. /FEA=mRNA /PROD=fructose-1,6-bisphosphatase /DB_XREF=gi:439225 /UG=Hs.574 fructose-1,6-bisphosphatase 1 /FL=gb:M19922.1 gb:L10320.1 gb:D26054.1 gb:D26055.1 gb:D26056.1 gb:NM_000507.1 D26054 fructose-1,6-bisphosphatase 1 FBP1 2203 NM_000507 /// NM_001127628 /// XM_006717005 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from mutant phenotype /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // traceable author statement /// 0006111 // regulation of gluconeogenesis // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045820 // negative regulation of glycolytic process // inferred from direct assay /// 0046580 // negative regulation of Ras protein signal transduction // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0071286 // cellular response to magnesium ion // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016208 // AMP binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042132 // fructose 1,6-bisphosphate 1-phosphatase activity // inferred from direct assay /// 0042132 // fructose 1,6-bisphosphate 1-phosphatase activity // inferred from mutant phenotype /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from mutant phenotype /// 0048029 // monosaccharide binding // inferred from sequence or structural similarity 209697_at BC004864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004864.1 /DEF=Homo sapiens, clone MGC:10576, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10576) /DB_XREF=gi:13436076 /UG=Hs.75206 protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) /FL=gb:BC004864.1 BC004864 Homo sapiens cDNA FLJ43872 fis, clone TESTI4008417. /// AK125860 /// RP11-582J16.4 209698_at AF216493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF216493.1 /DEF=Homo sapiens a-helical protein (HCR) mRNA, complete cds. /FEA=mRNA /GEN=HCR /PROD=a-helical protein /DB_XREF=gi:8272481 /UG=Hs.110746 HCR (a-helix coiled-coil rod homologue) /FL=gb:AB029331.1 gb:AF216493.1 gb:NM_019052.1 AF216493 coiled-coil alpha-helical rod protein 1 CCHCR1 54535 NM_001105563 /// NM_001105564 /// NM_019052 /// XM_005272832 /// XM_005272833 /// XM_005272835 /// XM_005272836 /// XM_005272839 /// XM_005272840 /// XM_005274987 /// XM_005274988 /// XM_005274990 /// XM_005274991 /// XM_005274994 /// XM_005274995 /// XM_005275137 /// XM_005275140 /// XM_005275265 /// XM_005275269 /// XM_005275422 /// XM_005275423 /// XM_006715119 /// XM_006725488 /// XM_006725702 /// XM_006725819 /// XM_006725911 /// XM_006726003 /// XM_006726004 0006611 // protein export from nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 209699_x_at U05598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U05598.1 /DEF=Human dihydrodiol dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=dihydrodiol dehydrogenase /DB_XREF=gi:531159 /UG=Hs.201967 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) /FL=gb:AB021654.1 gb:NM_001354.1 gb:U05598.1 gb:AB031083.1 gb:AB031084.1 U05598 aldo-keto reductase family 1, member C2 /// aldo-keto reductase family 1 member C2-like AKR1C2 /// LOC101930400 1646 /// 101930400 NM_001135241 /// NM_001354 /// NM_205845 /// XM_005276094 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay 209700_x_at AB042555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042555.1 /DEF=Homo sapiens mRNA, similar to rat myomegalin, complete cds. /FEA=mRNA /DB_XREF=gi:11138035 /UG=Hs.265848 similar to rat myomegalin /FL=gb:AB042555.1 gb:AB042556.1 AB042555 phosphodiesterase 4D interacting protein PDE4DIP 9659 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_005272981 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 209701_at D16217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D16217.1 /DEF=Human mRNA for calpastatin, complete cds. /FEA=mRNA /GEN=CAST /PROD=calpastatin /DB_XREF=gi:303598 /UG=Hs.279607 calpastatin /FL=gb:D16217.1 D16217 endoplasmic reticulum aminopeptidase 1 ERAP1 51752 NM_001040458 /// NM_001198541 /// NM_016442 /// XM_005272015 /// XM_005272016 0001525 // angiogenesis // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009617 // response to bacterium // inferred from expression pattern /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // non-traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement /// 0045088 // regulation of innate immune response // non-traceable author statement /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209702_at U79260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79260.1 /DEF=Human clone 23745 mRNA, complete cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1710215 /UG=Hs.284741 hypothetical protein MGC5149 /FL=gb:BC001284.1 gb:U79260.1 U79260 fat mass and obesity associated FTO 79068 NM_001080432 0001659 // temperature homeostasis // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006307 // DNA dealkylation involved in DNA repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010883 // regulation of lipid storage // inferred from electronic annotation /// 0035552 // oxidative single-stranded DNA demethylation // inferred from direct assay /// 0035553 // oxidative single-stranded RNA demethylation // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042245 // RNA repair // inferred from direct assay /// 0044065 // regulation of respiratory system process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0070350 // regulation of white fat cell proliferation // inferred from electronic annotation /// 0070989 // oxidative demethylation // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay 0008198 // ferrous iron binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0035515 // oxidative RNA demethylase activity // inferred from direct assay /// 0035516 // oxidative DNA demethylase activity // inferred from direct assay /// 0043734 // DNA-N1-methyladenine dioxygenase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 209703_x_at BC004492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004492.1 /DEF=Homo sapiens, clone MGC:11081, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11081) /DB_XREF=gi:13325369 /UG=Hs.288771 DKFZP586A0522 protein /FL=gb:BC004492.1 BC004492 methyltransferase like 7A METTL7A 25840 NM_014033 /// XM_006719332 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0009877 // nodulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 209704_at AL523380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523380 /FEA=EST /DB_XREF=gi:12786873 /DB_XREF=est:AL523380 /CLONE=CS0DC004YA03 (5 prime) /UG=Hs.31016 putative DNA binding protein /FL=gb:AF073293.1 AL523380 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209705_at BG033764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG033764 /FEA=EST /DB_XREF=gi:12426228 /DB_XREF=est:602302025F1 /CLONE=IMAGE:4403238 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF073293.1 BG033764 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209706_at AF247704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF247704.1 /DEF=Homo sapiens homeobox protein NKX3.1 mRNA, complete cds. /FEA=mRNA /PROD=homeobox protein NKX3.1 /DB_XREF=gi:9963969 /UG=Hs.55999 NK homeobox (Drosophila), family 3, A /FL=gb:AF249670.1 gb:AF249672.1 gb:U80669.1 gb:U91540.1 gb:NM_006167.1 gb:AF247704.1 AF247704 NK3 homeobox 1 NKX3-1 4824 NM_001256339 /// NM_006167 /// NR_046072 0001655 // urogenital system development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0007431 // salivary gland development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from sequence or structural similarity /// 0035690 // cellular response to drug // inferred from expression pattern /// 0035907 // dorsal aorta development // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071850 // mitotic cell cycle arrest // inferred from direct assay /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 2000836 // positive regulation of androgen secretion // inferred from direct assay /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004882 // androgen receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0097162 // MADS box domain binding // inferred from electronic annotation 209707_at AF022913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022913.1 /DEF=Homo sapiens GPI transamidase mRNA, complete cds. /FEA=mRNA /PROD=GPI transamidase /DB_XREF=gi:2558890 /UG=Hs.62187 phosphatidylinositol glycan, class K /FL=gb:AF022913.1 AF022913 phosphatidylinositol glycan anchor biosynthesis, class K PIGK 10026 NM_005482 0006457 // protein folding // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0042765 // GPI-anchor transamidase complex // inferred from mutant phenotype 0003756 // protein disulfide isomerase activity // traceable author statement /// 0003923 // GPI-anchor transamidase activity // inferred from mutant phenotype /// 0003923 // GPI-anchor transamidase activity // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034235 // GPI anchor binding // traceable author statement 209708_at AY007239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY007239.1 /DEF=Homo sapiens monooxygenase X mRNA, complete cds. /FEA=mRNA /PROD=monooxygenase X /DB_XREF=gi:9988949 /UG=Hs.6909 DKFZP564G202 protein /FL=gb:AY007239.1 AY007239 monooxygenase, DBH-like 1 MOXD1 26002 NM_015529 /// XM_006715456 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004500 // dopamine beta-monooxygenase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209709_s_at U29343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U29343.1 /DEF=Homo sapiens hyaluronan receptor (RHAMM) mRNA, complete cds. /FEA=mRNA /GEN=RHAMM /PROD=hyaluronan receptor /DB_XREF=gi:2959555 /UG=Hs.72550 hyaluronan-mediated motility receptor (RHAMM) /FL=gb:U29343.1 gb:AF032862.1 gb:NM_012484.1 U29343 hyaluronan-mediated motility receptor (RHAMM) HMMR 3161 NM_001142556 /// NM_001142557 /// NM_012484 /// NM_012485 0005975 // carbohydrate metabolic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005540 // hyaluronic acid binding // inferred from electronic annotation 209710_at AL563460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL563460 /FEA=EST /DB_XREF=gi:12912874 /DB_XREF=est:AL563460 /CLONE=CS0DD006YG06 (3 prime) /UG=Hs.760 GATA-binding protein 2 /FL=gb:M68891.1 AL563460 GATA binding protein 2 GATA2 2624 NM_001145661 /// NM_001145662 /// NM_032638 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0021514 // ventral spinal cord interneuron differentiation // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035065 // regulation of histone acetylation // inferred from electronic annotation /// 0035854 // eosinophil fate commitment // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048469 // cell maturation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060872 // semicircular canal development // inferred from electronic annotation /// 0070345 // negative regulation of fat cell proliferation // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 209711_at N80922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N80922 /FEA=EST /DB_XREF=gi:1243623 /DB_XREF=est:zb07e07.s1 /CLONE=IMAGE:301380 /UG=Hs.82635 KIAA0260 protein /FL=gb:AB044343.1 N80922 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 SLC35D1 23169 NM_015139 /// XM_006710478 /// XM_006710479 /// XM_006710480 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015781 // pyrimidine nucleotide-sugar transport // inferred from electronic annotation /// 0015787 // UDP-glucuronic acid transport // traceable author statement /// 0015789 // UDP-N-acetylgalactosamine transport // non-traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0052695 // cellular glucuronidation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090481 // pyrimidine nucleotide-sugar transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0005461 // UDP-glucuronic acid transmembrane transporter activity // traceable author statement /// 0005463 // UDP-N-acetylgalactosamine transmembrane transporter activity // non-traceable author statement /// 0015165 // pyrimidine nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation 209712_at AI769637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769637 /FEA=EST /DB_XREF=gi:5236146 /DB_XREF=est:wj25a12.x1 /CLONE=IMAGE:2403838 /UG=Hs.82635 KIAA0260 protein /FL=gb:AB044343.1 AI769637 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 SLC35D1 23169 NM_015139 /// XM_006710478 /// XM_006710479 /// XM_006710480 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015781 // pyrimidine nucleotide-sugar transport // inferred from electronic annotation /// 0015787 // UDP-glucuronic acid transport // traceable author statement /// 0015789 // UDP-N-acetylgalactosamine transport // non-traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0052695 // cellular glucuronidation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090481 // pyrimidine nucleotide-sugar transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0005461 // UDP-glucuronic acid transmembrane transporter activity // traceable author statement /// 0005463 // UDP-N-acetylgalactosamine transmembrane transporter activity // non-traceable author statement /// 0015165 // pyrimidine nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation 209713_s_at AB044343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044343.1 /DEF=Homo sapiens hUGTrel7 mRNA for UDP-glucuronic acid, complete cds. /FEA=mRNA /GEN=hUGTrel7 /PROD=UDP-glucuronic acid /DB_XREF=gi:11463948 /UG=Hs.82635 KIAA0260 protein /FL=gb:AB044343.1 AB044343 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 SLC35D1 23169 NM_015139 /// XM_006710478 /// XM_006710479 /// XM_006710480 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015781 // pyrimidine nucleotide-sugar transport // inferred from electronic annotation /// 0015787 // UDP-glucuronic acid transport // traceable author statement /// 0015789 // UDP-N-acetylgalactosamine transport // non-traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0052695 // cellular glucuronidation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090481 // pyrimidine nucleotide-sugar transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0005461 // UDP-glucuronic acid transmembrane transporter activity // traceable author statement /// 0005463 // UDP-N-acetylgalactosamine transmembrane transporter activity // non-traceable author statement /// 0015165 // pyrimidine nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation 209714_s_at AF213033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF213033.1 /DEF=Homo sapiens isolate BX-01 cyclin-dependent kinase associated protein phosphatase mRNA, complete cds. /FEA=mRNA /PROD=cyclin-dependent kinase associated proteinphosphatase /DB_XREF=gi:12734643 /UG=Hs.84113 cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) /FL=gb:AF213033.1 gb:AF213034.1 gb:AF213035.1 gb:AF213036.1 gb:AF213037.1 gb:AF213038.1 gb:AF213039.1 gb:AF213040.1 gb:AF213041.1 gb:AF213042.1 gb:AF213044.1 gb:AF213046.1 gb:AF213047.1 gb:AF213048.1 gb:AF213049.1 gb:AF213050.1 gb:AF213051.1 gb:AF213052.1 gb:AF213053.1 gb:U02681.1 gb:L25876.1 gb:NM_005192.1 gb:L27711.1 AF213033 cyclin-dependent kinase inhibitor 3 CDKN3 1033 NM_001130851 /// NM_005192 /// XM_005267258 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 209715_at L07515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L07515.1 /DEF=Human heterochromatin protein homologue (HP1) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:184310 /UG=Hs.89232 chromobox homolog 5 (Drosophila HP1 alpha) /FL=gb:L07515.1 gb:NM_012117.1 L07515 chromobox homolog 5 CBX5 23468 NM_001127321 /// NM_001127322 /// NM_012117 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from sequence or structural similarity /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation /// 0016605 // PML body // inferred from mutant phenotype /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0031618 // nuclear centromeric heterochromatin // non-traceable author statement /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity /// 1990226 // histone methyltransferase binding // inferred from physical interaction 209716_at M37435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M37435.1 /DEF=Human macrophage-specific colony-stimulating factor (CSF-1) mRNA, complete cds. /FEA=mRNA /GEN=CSF1 /DB_XREF=gi:181134 /UG=Hs.173894 colony stimulating factor 1 (macrophage) /FL=gb:M37435.1 gb:M64592.1 M37435 colony stimulating factor 1 (macrophage) CSF1 1435 NM_000757 /// NM_172210 /// NM_172211 /// NM_172212 0001503 // ossification // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0003006 // developmental process involved in reproduction // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010743 // regulation of macrophage derived foam cell differentiation // non-traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0030097 // hemopoiesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042117 // monocyte activation // non-traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042488 // positive regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060611 // mammary gland fat development // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay /// 0005157 // macrophage colony-stimulating factor receptor binding // inferred from sequence or structural similarity /// 0005157 // macrophage colony-stimulating factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 209717_at AF008915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF008915.1 /DEF=Homo sapiens EVI5 homolog mRNA, complete cds. /FEA=mRNA /PROD=EVI-5 homolog /DB_XREF=gi:3093475 /UG=Hs.179747 ecotropic viral integration site 5 /FL=gb:AF008915.1 AF008915 ecotropic viral integration site 5 EVI5 7813 NM_005665 /// XM_005271179 /// XM_005271180 /// XM_005271182 /// XM_006710884 /// XM_006710885 /// XM_006710886 /// XM_006710887 /// XM_006710888 /// XM_006710889 /// XM_006710890 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209718_at BC001298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001298.1 /DEF=Homo sapiens, Similar to hypothetical protein 384D8_6, clone MGC:5305, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein 384D8_6 /DB_XREF=gi:12654904 /UG=Hs.180903 hypothetical protein 384D8_6 /FL=gb:BC001298.1 BC001298 non-SMC condensin II complex, subunit H2 NCAPH2 29781 NM_001185011 /// NM_014551 /// NM_152299 /// XM_005261912 0000278 // mitotic cell cycle // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from direct assay 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209719_x_at U19556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19556.1 /DEF=Human squamous cell carcinoma antigen 1 (SCCA1) mRNA, complete cds. /FEA=mRNA /GEN=SCCA1 /PROD=squamous cell carcinoma antigen 1 /DB_XREF=gi:1276435 /UG=Hs.227948 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 /FL=gb:U19556.1 gb:BC005224.1 gb:NM_006919.1 U19556 serpin peptidase inhibitor, clade B (ovalbumin), member 3 SERPINB3 6317 NM_006919 0009615 // response to virus // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 209720_s_at BC005224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005224.1 /DEF=Homo sapiens, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3, clone MGC:12244, mRNA, complete cds. /FEA=mRNA /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 3 /DB_XREF=gi:13528851 /UG=Hs.227948 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 /FL=gb:U19556.1 gb:BC005224.1 gb:NM_006919.1 BC005224 serpin peptidase inhibitor, clade B (ovalbumin), member 3 SERPINB3 6317 NM_006919 0009615 // response to virus // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 209721_s_at BC002857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002857.1 /DEF=Homo sapiens, clone MGC:3442, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3442) /DB_XREF=gi:12804008 /UG=Hs.46659 DKFZP586I2223 protein /FL=gb:BC002857.1 gb:BC001790.1 gb:NM_015438.1 gb:BC004384.1 BC002857 intermediate filament family orphan 1 IFFO1 25900 NM_001039670 /// NM_001193457 /// NM_001193459 /// NM_015438 /// NM_080730 /// NM_080731 /// NR_036467 /// XM_006718973 /// XM_006718974 /// XM_006718975 /// XM_006718976 /// XM_006718977 /// XM_006718978 /// XM_006718979 /// XM_006718980 /// XM_006718981 /// XM_006718982 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 209722_s_at L40378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L40378.1 /DEF=Homo sapiens cytoplasmic antiproteinase 3 (CAP3) mRNA, complete cds. /FEA=mRNA /GEN=CAP3 /PROD=cytoplasmic antiproteinase 3 /DB_XREF=gi:1160928 /UG=Hs.104879 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 /FL=gb:L40378.1 gb:BC002538.1 gb:U71364.1 gb:NM_004155.1 L40378 serpin peptidase inhibitor, clade B (ovalbumin), member 9 SERPINB9 5272 NM_004155 /// XM_005249184 0002448 // mast cell mediated immunity // inferred from expression pattern /// 0006955 // immune response // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0071391 // cellular response to estrogen stimulus // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype 209723_at BC002538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002538.1 /DEF=Homo sapiens, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, clone MGC:2131, mRNA, complete cds. /FEA=mRNA /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 9 /DB_XREF=gi:12803428 /UG=Hs.104879 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 /FL=gb:L40378.1 gb:BC002538.1 gb:U71364.1 gb:NM_004155.1 BC002538 serpin peptidase inhibitor, clade B (ovalbumin), member 9 SERPINB9 5272 NM_004155 /// XM_005249184 0002448 // mast cell mediated immunity // inferred from expression pattern /// 0006955 // immune response // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0071391 // cellular response to estrogen stimulus // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype 209724_s_at AL534416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL534416 /FEA=EST /DB_XREF=gi:12797909 /DB_XREF=est:AL534416 /CLONE=CS0DF004YN12 (3 prime) /UG=Hs.156000 zinc finger protein homologous to Zfp161 in mouse /FL=gb:D89859.1 AL534416 zinc finger and BTB domain containing 14 ZBTB14 7541 NM_001143823 /// NM_001243702 /// NM_001243704 /// NM_003409 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209725_at AF072718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072718.1 /DEF=Homo sapiens Key-1A6 protein mRNA, complete cds. /FEA=mRNA /PROD=Key-1A6 protein /DB_XREF=gi:11464475 /UG=Hs.178614 down-regulated in metastasis /FL=gb:AF072718.1 gb:NM_014503.1 AF072718 UTP20, small subunit (SSU) processome component, homolog (yeast) UTP20 27340 NM_014503 /// XM_006719343 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0000472 // endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0000480 // endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030686 // 90S preribosome // inferred from sequence or structural similarity /// 0030688 // preribosome, small subunit precursor // inferred from sequence or structural similarity /// 0032040 // small-subunit processome // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209726_at AB018195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB018195.1 /DEF=Homo sapiens ca xi mRNA for carbonic anhydrase-related protein XI, complete cds. /FEA=mRNA /GEN=ca xi /PROD=carbonic anhydrase-related protein XI /DB_XREF=gi:4126973 /UG=Hs.22777 carbonic anhydrase XI /FL=gb:BC002662.1 gb:AF067662.1 gb:AB018195.1 gb:NM_001217.2 AB018195 carbonic anhydrase XI CA11 770 NM_001217 /// XR_243956 0005576 // extracellular region // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // traceable author statement 209727_at M76477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76477.1 /DEF=Human G-M2 activator protein mRNA, complete cds. /FEA=mRNA /PROD=G-M2 activator protein /DB_XREF=gi:183356 /UG=Hs.289082 GM2 ganglioside activator protein /FL=gb:M76477.1 gb:L01439.1 gb:NM_000405.1 M76477 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019377 // glycolipid catabolic process // non-traceable author statement /// 0019915 // lipid storage // inferred from electronic annotation /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030290 // sphingolipid activator protein activity // non-traceable author statement 209728_at BC005312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005312.1 /DEF=Homo sapiens, clone MGC:12387, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12387) /DB_XREF=gi:13529055 /UG=Hs.318720 Homo sapiens, clone MGC:12387, mRNA, complete cds /FL=gb:BC005312.1 gb:M16942.1 BC005312 major histocompatibility complex, class II, DR beta 4 HLA-DRB4 3126 NM_021983 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 209729_at BC001782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001782.1 /DEF=Homo sapiens, GAS2-related on chromosome 22, clone MGC:2104, mRNA, complete cds. /FEA=mRNA /PROD=GAS2-related on chromosome 22 /DB_XREF=gi:12804706 /UG=Hs.322852 Homo sapiens, GAS2-related on chromosome 22, clone MGC:2104, mRNA, complete cds /FL=gb:BC001782.1 BC001782 growth arrest-specific 2 like 1 GAS2L1 10634 NM_001278730 /// NM_006478 /// NM_152236 /// NM_152237 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 209730_at U38276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38276.1 /DEF=Human semaphorin III family homolog mRNA, complete cds. /FEA=mRNA /PROD=semaphorin III family homolog /DB_XREF=gi:1061350 /UG=Hs.32981 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F /FL=gb:U38276.1 U38276 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F SEMA3F 6405 NM_004186 /// XM_005265381 /// XM_005265382 /// XM_006713289 /// XM_006713290 0001755 // neural crest cell migration // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from direct assay 209731_at U79718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79718.1 /DEF=Human endonuclease III homolog 1 (OCTS3) mRNA, complete cds. /FEA=mRNA /GEN=OCTS3 /PROD=endonuclease III homolog 1, hNTH1 /DB_XREF=gi:1800270 /UG=Hs.66196 nth (E.coli endonuclease III)-like 1 /FL=gb:BC000391.1 gb:BC003014.1 gb:U81285.1 gb:U79718.1 gb:AB001575.1 gb:NM_002528.3 U79718 nth endonuclease III-like 1 (E. coli) NTHL1 4913 NM_002528 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // inferred from direct assay /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0004519 // endonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 209732_at BC005254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005254.1 /DEF=Homo sapiens, Similar to C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced), clone MGC:12289, mRNA, complete cds. /FEA=mRNA /PROD=Similar to C-type (calcium dependent,carbohydrate-recognition domain) lectin, superfamilymember 2 (activation-induced) /DB_XREF=gi:13528920 /UG=Hs.85201 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced) /FL=gb:BC005254.1 gb:AB015628.1 gb:NM_005127.1 BC005254 C-type lectin domain family 2, member B CLEC2B 9976 NM_005127 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030246 // carbohydrate binding // inferred from electronic annotation 209733_at AL034399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034399 /DEF=Human DNA sequence from clone 191P20 on chromosome Xq23. Contains a pseudogene similar to AngiotensinVasopressin receptor AIIAVP, and the 3 end of a novel Fibronectin type III domain containing protein similar to Ring finger protein MID1 (Midli... /FEA=mRNA /DB_XREF=gi:4493484 /UG=Hs.12256 midline 2 /FL=gb:AF196481.1 AL034399 midline 2 MID2 11043 NM_012216 /// NM_052817 /// XM_005262062 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 209734_at BC001604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001604.1 /DEF=Homo sapiens, hematopoietic protein 1, clone MGC:2204, mRNA, complete cds. /FEA=mRNA /PROD=hematopoietic protein 1 /DB_XREF=gi:12804404 /UG=Hs.132834 hematopoietic protein 1 /FL=gb:BC001604.1 gb:M58285.1 gb:NM_005337.1 BC001604 NCK-associated protein 1-like NCKAP1L 3071 NM_001184976 /// NM_005337 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0002262 // myeloid cell homeostasis // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035509 // negative regulation of myosin-light-chain-phosphatase activity // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from mutant phenotype /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043372 // positive regulation of CD4-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0043378 // positive regulation of CD8-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0045579 // positive regulation of B cell differentiation // inferred from sequence or structural similarity /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from sequence or structural similarity /// 0045621 // positive regulation of lymphocyte differentiation // inferred from sequence or structural similarity /// 0045648 // positive regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from expression pattern /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from sequence or structural similarity /// 0070358 // actin polymerization-dependent cell motility // inferred from mutant phenotype /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from mutant phenotype /// 0030675 // Rac GTPase activator activity // inferred from mutant phenotype /// 0032403 // protein complex binding // inferred from direct assay 209735_at AF098951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098951.2 /DEF=Homo sapiens breast cancer resistance protein (BCRP) mRNA, complete cds. /FEA=mRNA /GEN=BCRP /PROD=breast cancer resistance protein /DB_XREF=gi:12414050 /UG=Hs.194720 ATP-binding cassette, sub-family G (WHITE), member 2 /FL=gb:AF098951.2 gb:AB056867.1 gb:AF103796.1 gb:NM_004827.1 AF098951 ATP-binding cassette, sub-family G (WHITE), member 2 ABCG2 9429 NM_001257386 /// NM_004827 /// XM_005263354 /// XM_005263355 /// XM_005263356 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0015886 // heme transport // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0042908 // xenobiotic transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008559 // xenobiotic-transporting ATPase activity // traceable author statement /// 0015232 // heme transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 209736_at AF116571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116571.1 /DEF=Homo sapiens SRY-like DNA binding protein (SOX13) mRNA, complete cds. /FEA=mRNA /GEN=SOX13 /PROD=SRY-like DNA binding protein /DB_XREF=gi:6689860 /UG=Hs.201671 SRY (sex determining region Y)-box 13 /FL=gb:AF083105.1 gb:AF098915.1 gb:NM_005686.1 gb:AF116571.1 AF116571 SRY (sex determining region Y)-box 13 SOX13 9580 NM_005686 /// XM_005245623 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 209737_at AB014605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014605.1 /DEF=Homo sapiens mRNA for KIAA0705 protein, complete cds. /FEA=mRNA /GEN=KIAA0705 /PROD=KIAA0705 protein /DB_XREF=gi:3327223 /UG=Hs.22599 atrophin-1 interacting protein 1; activin receptor interacting protein 1 /FL=gb:AB014605.1 AB014605 membrane associated guanylate kinase, WW and PDZ domain containing 2 MAGI2 9863 NM_012301 /// XM_005250725 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0003402 // planar cell polarity pathway involved in axis elongation // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from sequence or structural similarity /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from sequence or structural similarity /// 0070699 // type II activin receptor binding // inferred from sequence or structural similarity 209738_x_at M31125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31125.1 /DEF=Human pregnancy-specific-beta 1-glycoprotein (PS1) mRNA, complete cds, clone hPS12. /FEA=mRNA /DB_XREF=gi:190619 /UG=Hs.252097 pregnancy specific beta-1-glycoprotein 6 /FL=gb:M31125.1 M31125 pregnancy specific beta-1-glycoprotein 6 PSG6 5675 NM_001031850 /// NM_002782 0007565 // female pregnancy // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 209739_s_at AI814551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814551 /FEA=EST /DB_XREF=gi:5425766 /DB_XREF=est:wj74e05.x1 /CLONE=IMAGE:2408576 /UG=Hs.264 GS2 gene /FL=gb:U03886.1 AI814551 patatin-like phospholipase domain containing 4 PNPLA4 8228 NM_001142389 /// NM_001172672 /// NM_004650 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209740_s_at U03886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03886.1 /DEF=Human GS2 mRNA, complete cds. /FEA=mRNA /GEN=GS2 /DB_XREF=gi:458225 /UG=Hs.264 GS2 gene /FL=gb:U03886.1 U03886 patatin-like phospholipase domain containing 4 PNPLA4 8228 NM_001142389 /// NM_001172672 /// NM_004650 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209741_x_at AF119814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119814.1 /DEF=Homo sapiens MSTP063 mRNA, complete cds. /FEA=mRNA /PROD=MSTP063 /DB_XREF=gi:12056567 /UG=Hs.285848 KIAA1454 protein /FL=gb:AF119814.1 AF119814 S-phase cyclin A-associated protein in the ER SCAPER 49855 NM_001145923 /// NM_020843 /// XM_005254417 /// XM_005254419 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209742_s_at AF020768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020768.1 /DEF=Homo sapiens cardiac ventricular myosin light chain 2 mRNA, complete cds. /FEA=mRNA /PROD=cardiac ventricular myosin light chain 2 /DB_XREF=gi:2460246 /UG=Hs.75535 myosin, light polypeptide 2, regulatory, cardiac, slow /FL=gb:M22815.1 gb:AF020768.1 gb:NM_000432.1 AF020768 myosin, light chain 2, regulatory, cardiac, slow MYL2 4633 NM_000432 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0042694 // muscle cell fate specification // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from sequence or structural similarity /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0030016 // myofibril // non-traceable author statement /// 0030017 // sarcomere // traceable author statement /// 0031672 // A band // inferred from electronic annotation 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0032036 // myosin heavy chain binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 209743_s_at AI989677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI989677 /FEA=EST /DB_XREF=gi:5836558 /DB_XREF=est:ws35b04.x1 /CLONE=IMAGE:2499151 /UG=Hs.98074 atrophin-1 interacting protein 4 /FL=gb:AB056663.2 AI989677 itchy E3 ubiquitin protein ligase ITCH 83737 NM_001257137 /// NM_001257138 /// NM_031483 /// XM_005260570 /// XM_006723881 /// XM_006723882 /// XR_244153 /// XR_430315 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046718 // viral entry into host cell // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0090085 // regulation of protein deubiquitination // inferred from sequence or structural similarity 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0045236 // CXCR chemokine receptor binding // inferred from physical interaction 209744_x_at AB056663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB056663.2 /DEF=Homo sapiens mRNA for ubiquitin protein ligase Itch, complete cds. /FEA=mRNA /GEN=Itch /PROD=ubiquitin protein ligase Itch /DB_XREF=gi:13442821 /UG=Hs.98074 atrophin-1 interacting protein 4 /FL=gb:AB056663.2 AB056663 itchy E3 ubiquitin protein ligase ITCH 83737 NM_001257137 /// NM_001257138 /// NM_031483 /// XM_005260570 /// XM_006723881 /// XM_006723882 /// XR_244153 /// XR_430315 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046718 // viral entry into host cell // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0090085 // regulation of protein deubiquitination // inferred from sequence or structural similarity 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0045236 // CXCR chemokine receptor binding // inferred from physical interaction 209745_at AK024291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024291.1 /DEF=Homo sapiens cDNA FLJ14229 fis, clone NT2RP3004155, highly similar to Homo sapiens COQ7 protein mRNA. /FEA=mRNA /DB_XREF=gi:10436637 /UG=Hs.157113 coenzyme Q, 7 (rat, yeast) homolog /FL=gb:BC003185.1 gb:AF032900.1 gb:AF098948.1 gb:NM_016138.1 AK024291 coenzyme Q7 homolog, ubiquinone (yeast) COQ7 10229 NM_001190983 /// NM_016138 /// XM_005255033 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 209746_s_at AF032900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF032900.1 /DEF=Homo sapiens timing protein CLK-1 mRNA, complete cds. /FEA=mRNA /PROD=timing protein CLK-1 /DB_XREF=gi:3811294 /UG=Hs.157113 coenzyme Q, 7 (rat, yeast) homolog /FL=gb:BC003185.1 gb:AF032900.1 gb:AF098948.1 gb:NM_016138.1 AF032900 coenzyme Q7 homolog, ubiquinone (yeast) COQ7 10229 NM_001190983 /// NM_016138 /// XM_005255033 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 209747_at J03241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03241.1 /DEF=Human transforming growth factor-beta 3 (TGF-beta3) mRNA, complete cds. /FEA=mRNA /GEN=TGFB3 /DB_XREF=gi:339551 /UG=Hs.2025 transforming growth factor, beta 3 /FL=gb:J03241.1 gb:NM_003239.1 J03241 transforming growth factor, beta 3 TGFB3 7043 NM_003239 /// XM_005268028 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030501 // positive regulation of bone mineralization // inferred from expression pattern /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042476 // odontogenesis // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043932 // ossification involved in bone remodeling // inferred from expression pattern /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity /// 0070483 // detection of hypoxia // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay 209748_at AB029006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB029006.1 /DEF=Homo sapiens mRNA for KIAA1083 protein, complete cds. /FEA=mRNA /GEN=KIAA1083 /PROD=KIAA1083 protein /DB_XREF=gi:5689502 /UG=Hs.26334 spastic paraplegia 4 (autosomal dominant; spastin) /FL=gb:AB029006.1 AB029006 spastin SPAST 6683 NM_014946 /// NM_199436 /// XM_005264516 0001578 // microtubule bundle formation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from electronic annotation /// 0034214 // protein hexamerization // inferred from direct assay /// 0051013 // microtubule severing // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from physical interaction 209749_s_at AI623989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI623989 /FEA=EST /DB_XREF=gi:4648920 /DB_XREF=est:ts25c07.x1 /CLONE=IMAGE:2229612 /UG=Hs.298469 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 /FL=gb:M26658.1 AI623989 angiotensin I converting enzyme ACE 1636 NM_000789 /// NM_001178057 /// NM_152830 /// NM_152831 /// XM_005257110 /// XM_006721737 0001822 // kidney development // inferred from mutant phenotype /// 0001974 // blood vessel remodeling // inferred by curator /// 0002003 // angiotensin maturation // traceable author statement /// 0002005 // angiotensin catabolic process in blood // inferred by curator /// 0002019 // regulation of renal output by angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0014910 // regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0032943 // mononuclear cell proliferation // inferred by curator /// 0042312 // regulation of vasodilation // inferred by curator /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from sequence or structural similarity /// 0043171 // peptide catabolic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0060218 // hematopoietic stem cell differentiation // inferred by curator 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from sequence or structural similarity /// 0008241 // peptidyl-dipeptidase activity // inferred from direct assay /// 0008241 // peptidyl-dipeptidase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from direct assay /// 0031711 // bradykinin receptor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209750_at N32859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32859 /FEA=EST /DB_XREF=gi:1153258 /DB_XREF=est:yw88d02.s1 /CLONE=IMAGE:259299 /UG=Hs.37288 nuclear receptor subfamily 1, group D, member 2 /FL=gb:D16815.1 N32859 nuclear receptor subfamily 1, group D, member 2 NR1D2 9975 NM_001145425 /// NM_005126 /// NR_110524 /// XM_005265639 /// XM_006713451 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209751_s_at AF291676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF291676.1 /DEF=Homo sapiens MBP-1 interacting protein-2A mRNA, complete cds. /FEA=mRNA /PROD=MBP-1 interacting protein-2A /DB_XREF=gi:9937492 /UG=Hs.5699 spondyloepiphyseal dysplasia, late, pseudogene /FL=gb:NM_015890.1 gb:AF291676.1 AF291676 trafficking protein particle complex 2 /// trafficking protein particle complex 2 pseudogene 1 TRAPPC2 /// TRAPPC2P1 6399 /// 10597 NM_001011658 /// NM_001128835 /// NM_014563 /// NR_002166 0001501 // skeletal system development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209752_at AF172331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF172331.1 /DEF=Homo sapiens lithostathine (REG1A) mRNA, complete cds. /FEA=mRNA /GEN=REG1A /PROD=lithostathine /DB_XREF=gi:5764554 /UG=Hs.1032 regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein) /FL=gb:BC005350.1 gb:M18963.1 gb:NM_002909.1 gb:AF172331.1 gb:M27190.1 AF172331 regenerating islet-derived 1 alpha REG1A 5967 NM_002909 0008284 // positive regulation of cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008083 // growth factor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation 209753_s_at BG391171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG391171 /FEA=EST /DB_XREF=gi:13284619 /DB_XREF=est:602417192F1 /CLONE=IMAGE:4536623 /UG=Hs.11355 thymopoietin /FL=gb:U09087.1 gb:AF113682.1 BG391171 thymopoietin TMPO 7112 NM_001032283 /// NM_001032284 /// NM_003276 /// XM_005269130 /// XM_005269132 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement 209754_s_at AF113682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113682.1 /DEF=Homo sapiens clone FLB3436 PRO0868 mRNA, complete cds. /FEA=mRNA /PROD=PRO0868 /DB_XREF=gi:6855608 /UG=Hs.11355 thymopoietin /FL=gb:U09087.1 gb:AF113682.1 AF113682 thymopoietin TMPO 7112 NM_001032283 /// NM_001032284 /// NM_003276 /// XM_005269130 /// XM_005269132 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement 209755_at AF288395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288395.1 /DEF=Homo sapiens C1orf15 mRNA, complete cds. /FEA=mRNA /PROD=C1orf15 /DB_XREF=gi:12620199 /UG=Hs.158244 KIAA0479 protein /FL=gb:AF288395.1 AF288395 nicotinamide nucleotide adenylyltransferase 2 NMNAT2 23057 NM_015039 /// NM_170706 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred by curator /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000309 // nicotinamide-nucleotide adenylyltransferase activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004515 // nicotinate-nucleotide adenylyltransferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 209756_s_at AI871354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871354 /FEA=EST /DB_XREF=gi:5545403 /DB_XREF=est:wl81b06.x1 /CLONE=IMAGE:2431283 /UG=Hs.25960 v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived /FL=gb:BC002712.1 gb:NM_005378.1 AI871354 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog MYCN 4613 NM_001293228 /// NM_001293231 /// NM_001293233 /// NM_005378 /// XM_006711886 0001502 // cartilage condensation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209757_s_at BC002712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002712.1 /DEF=Homo sapiens, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived, clone MGC:3962, mRNA, complete cds. /FEA=mRNA /PROD=v-myc avian myelocytomatosis viral relatedoncogene, neuroblastoma derived /DB_XREF=gi:12803748 /UG=Hs.25960 v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived /FL=gb:BC002712.1 gb:NM_005378.1 BC002712 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog MYCN 4613 NM_001293228 /// NM_001293231 /// NM_001293233 /// NM_005378 /// XM_006711886 0001502 // cartilage condensation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209758_s_at U37283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U37283.1 /DEF=Human microfibril-associated glycoprotein-2 MAGP-2 mRNA, complete cds. /FEA=mRNA /PROD=microfibril-associated glycoprotein-2 MAGP-2 /DB_XREF=gi:1165211 /UG=Hs.300946 Microfibril-associated glycoprotein-2 /FL=gb:U37283.1 gb:NM_003480.1 U37283 microfibrillar associated protein 5 MFAP5 8076 NM_003480 /// XM_005253485 /// XM_006719154 /// XR_242903 /// XR_242904 0030198 // extracellular matrix organization // traceable author statement /// 0043206 // extracellular fibril organization // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement 209759_s_at BC002746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002746.1 /DEF=Homo sapiens, Similar to dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase), clone MGC:3903, mRNA, complete cds. /FEA=mRNA /PROD=Similar to dodecenoyl-Coenzyme A delta isomerase(3,2 trans-enoyl-Coenzyme A isomerase) /DB_XREF=gi:12803812 /UG=Hs.322824 Homo sapiens, Similar to dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase), clone MGC:3903, mRNA, complete cds /FL=gb:BC002746.1 BC002746 enoyl-CoA delta isomerase 1 ECI1 1632 NM_001178029 /// NM_001919 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // non-traceable author statement /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004165 // dodecenoyl-CoA delta-isomerase activity // non-traceable author statement /// 0004165 // dodecenoyl-CoA delta-isomerase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016860 // intramolecular oxidoreductase activity // traceable author statement 209760_at AL136932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136932.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H1322 (from clone DKFZp586H1322); complete cds. /FEA=mRNA /GEN=DKFZp586H1322 /PROD=hypothetical protein /DB_XREF=gi:12053358 /UG=Hs.37892 KIAA0922 protein /FL=gb:AL136932.1 AL136932 KIAA0922 KIAA0922 23240 NM_001131007 /// NM_015196 /// XM_005262869 /// XM_005262870 /// XM_005262871 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 209761_s_at AA969194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA969194 /FEA=EST /DB_XREF=gi:3144374 /DB_XREF=est:op51c02.s1 /CLONE=IMAGE:1580354 /UG=Hs.38125 interferon-induced protein 75, 52kD /FL=gb:AF280094.1 AA969194 SP110 nuclear body protein SP110 3431 NM_001185015 /// NM_004509 /// NM_004510 /// NM_080424 /// XM_005246525 /// XM_005246527 /// XM_006712486 /// XM_006712487 /// XM_006712488 /// XM_006712489 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209762_x_at AF280094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280094.1 /DEF=Homo sapiens transcriptional coactivator Sp110b mRNA, complete cds. /FEA=mRNA /PROD=transcriptional coactivator Sp110b /DB_XREF=gi:9800493 /UG=Hs.38125 interferon-induced protein 75, 52kD /FL=gb:AF280094.1 AF280094 SP110 nuclear body protein SP110 3431 NM_001185015 /// NM_004509 /// NM_004510 /// NM_080424 /// XM_005246525 /// XM_005246527 /// XM_006712486 /// XM_006712487 /// XM_006712488 /// XM_006712489 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209763_at AL049176 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049176 /DEF=Human DNA sequence from clone 141H5 on chromosome Xq22.1-23. Contains parts of a novel Chordin LIKE protein with von Willebrand factor type C domains. Contains ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:4808226 /UG=Hs.82223 chordin-like /FL=gb:BC002909.1 AL049176 chordin-like 1 CHRDL1 91851 NM_001143981 /// NM_001143982 /// NM_001143983 /// NM_145234 /// XM_005262221 /// XM_005262222 /// XM_005262223 /// XM_005262224 0001503 // ossification // inferred from electronic annotation /// 0001654 // eye development // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0048749 // compound eye development // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement 0005515 // protein binding // inferred from electronic annotation 209764_at AL022312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022312 /DEF=Human DNA sequence from clone RP5-1104E15 on chromosome 22q12.3-13.1 Contains the MGAT3 gene for mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, the gene for a predicted protein, the ATF4 gene for activating transcripti... /FEA=mRNA_3 /DB_XREF=gi:4914501 /UG=Hs.112 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase /FL=gb:D13789.1 AL022312 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase MGAT3 4248 NM_001098270 /// NM_002409 /// XM_005261608 /// XM_005261609 /// XM_006724252 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003830 // beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 209765_at Y13786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y13786.2 /DEF=Homo sapiens mRNA for meltrin-betaADAM 19 homologue. /FEA=mRNA /PROD=meltrin-betaADAM 19 homologue /DB_XREF=gi:12053590 /UG=Hs.278679 a disintegrin and metalloproteinase domain 19 (meltrin beta) /FL=gb:AF311317.1 Y13786 ADAM metallopeptidase domain 19 ADAM19 8728 NM_023038 /// NM_033274 /// XM_005266003 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209766_at AF118073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118073.1 /DEF=Homo sapiens PRO1748 mRNA, complete cds. /FEA=mRNA /PROD=PRO1748 /DB_XREF=gi:6650791 /UG=Hs.278923 PRO1748 protein /FL=gb:AF118073.1 AF118073 peroxiredoxin 3 PRDX3 10935 NM_006793 /// NM_014098 0001893 // maternal placenta development // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018171 // peptidyl-cysteine oxidation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from genetic interaction /// 0042744 // hydrogen peroxide catabolic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008785 // alkyl hydroperoxide reductase activity // non-traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 209767_s_at AA702163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA702163 /FEA=EST /DB_XREF=gi:2705276 /DB_XREF=est:zi91f06.s1 /CLONE=IMAGE:448163 /UG=Hs.283743 glycoprotein Ib (platelet), beta polypeptide /FL=gb:L20860.1 AA702163 glycoprotein Ib (platelet), beta polypeptide /// septin 5 /// SEPT5-GP1BB readthrough GP1BB /// SEPT5 /// SEPT5-GP1BB 2812 /// 5413 /// 100526833 NM_000407 /// NM_001009939 /// NM_002688 /// NR_037611 /// NR_037612 0000910 // cytokinesis // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // traceable author statement /// 0017157 // regulation of exocytosis // inferred from mutant phenotype /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 209768_s_at AI860917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI860917 /FEA=EST /DB_XREF=gi:5514533 /DB_XREF=est:wl56b07.x1 /CLONE=IMAGE:2428885 /UG=Hs.283743 glycoprotein Ib (platelet), beta polypeptide /FL=gb:L20860.1 AI860917 SEPT5-GP1BB readthrough SEPT5-GP1BB 100526833 NR_037611 /// NR_037612 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209769_s_at L20860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20860.1 /DEF=Human glycoprotein Ib beta mRNA, complete cds. /FEA=mRNA /PROD=glycoprotein Ib beta /DB_XREF=gi:438627 /UG=Hs.283743 glycoprotein Ib (platelet), beta polypeptide /FL=gb:L20860.1 L20860 SEPT5-GP1BB readthrough SEPT5-GP1BB 100526833 NR_037611 /// NR_037612 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209770_at U90552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90552.1 /DEF=Human butyrophilin (BTF5) mRNA, complete cds. /FEA=mRNA /GEN=BTF5 /PROD=butyrophilin /DB_XREF=gi:2062705 /UG=Hs.284283 butyrophilin, subfamily 3, member A1 /FL=gb:U90552.1 U90552 butyrophilin, subfamily 3, member A1 BTN3A1 11119 NM_001145008 /// NM_001145009 /// NM_007048 /// NM_194441 /// XM_005248833 /// XM_005248834 /// XM_006714983 0002376 // immune system process // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from direct assay /// 0050798 // activated T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209771_x_at AA761181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA761181 /FEA=EST /DB_XREF=gi:2810111 /DB_XREF=est:nz09g03.s1 /CLONE=IMAGE:1287316 /UG=Hs.286124 CD24 antigen (small cell lung carcinoma cluster 4 antigen) /FL=gb:X69397.1 AA761181 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 209772_s_at X69397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:X69397.1 /DEF=H.sapiens CD24 gene, complete CDS. /FEA=mRNA /GEN=CD24 /PROD=cell surface antigen /DB_XREF=gi:396167 /UG=Hs.286124 CD24 antigen (small cell lung carcinoma cluster 4 antigen) /FL=gb:X69397.1 X69397 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 209773_s_at BC001886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001886.1 /DEF=Homo sapiens, ribonucleotide reductase M2 polypeptide, clone MGC:1551, mRNA, complete cds. /FEA=mRNA /PROD=ribonucleotide reductase M2 polypeptide /DB_XREF=gi:12804874 /UG=Hs.75319 ribonucleotide reductase M2 polypeptide /FL=gb:BC001886.1 BC001886 ribonucleotide reductase M2 RRM2 6241 NM_001034 /// NM_001165931 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009186 // deoxyribonucleoside diphosphate metabolic process // inferred from electronic annotation /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 209774_x_at M57731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57731.1 /DEF=Human gro-beta mRNA, complete cds. /FEA=mRNA /GEN=gro-beta /PROD=cytokine gro-beta /DB_XREF=gi:183626 /UG=Hs.75765 GRO2 oncogene /FL=gb:M57731.1 gb:M36820.1 gb:NM_002089.1 M57731 chemokine (C-X-C motif) ligand 2 CXCL2 2920 NM_002089 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation 209775_x_at AI917627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI917627 /FEA=EST /DB_XREF=gi:5637482 /DB_XREF=est:wi36a11.x1 /CLONE=IMAGE:2392316 /UG=Hs.84190 solute carrier family 19 (folate transporter), member 1 /FL=gb:U15939.1 gb:AF004354.1 gb:NM_003056.1 gb:U19720.1 gb:U17566.1 AI917627 solute carrier family 19 (folate transporter), member 1 SLC19A1 6573 NM_001205206 /// NM_001205207 /// NM_003056 /// NM_194255 /// XM_005261164 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0051958 // methotrexate transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005542 // folic acid binding // inferred from electronic annotation /// 0008517 // folic acid transporter activity // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015350 // methotrexate transporter activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 209776_s_at U15939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U15939.1 /DEF=Human placental folate transporter (hFOLT1) mRNA, complete cds. /FEA=mRNA /GEN=hFOLT1 /PROD=placental folate transporter /DB_XREF=gi:1222522 /UG=Hs.84190 solute carrier family 19 (folate transporter), member 1 /FL=gb:U15939.1 gb:AF004354.1 gb:NM_003056.1 gb:U19720.1 gb:U17566.1 U15939 uncharacterized LOC101928717 /// solute carrier family 19 (folate transporter), member 1 LOC101928717 /// SLC19A1 6573 /// 101928717 NM_001205206 /// NM_001205207 /// NM_003056 /// NM_194255 /// XM_005261164 /// XR_244332 /// XR_249004 /// XR_254049 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0051958 // methotrexate transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005542 // folic acid binding // inferred from electronic annotation /// 0008517 // folic acid transporter activity // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015350 // methotrexate transporter activity // inferred from electronic annotation 209777_s_at AF004354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004354.1 /DEF=Homo sapiens folate carrier mRNA, complete cds. /FEA=mRNA /PROD=folate carrier /DB_XREF=gi:2209134 /UG=Hs.84190 solute carrier family 19 (folate transporter), member 1 /FL=gb:U15939.1 gb:AF004354.1 gb:NM_003056.1 gb:U19720.1 gb:U17566.1 AF004354 uncharacterized LOC101928717 /// solute carrier family 19 (folate transporter), member 1 LOC101928717 /// SLC19A1 6573 /// 101928717 NM_001205206 /// NM_001205207 /// NM_003056 /// NM_194255 /// XM_005261164 /// XR_244332 /// XR_249004 /// XR_254049 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0051958 // methotrexate transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005542 // folic acid binding // inferred from electronic annotation /// 0008517 // folic acid transporter activity // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015350 // methotrexate transporter activity // inferred from electronic annotation 209778_at AF007217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF007217.1 /DEF=Homo sapiens Trip230 mRNA, complete cds. /FEA=mRNA /GEN=Trip230 /PROD=Trip230 /DB_XREF=gi:2253416 /UG=Hs.85092 thyroid hormone receptor interactor 11 /FL=gb:NM_004239.1 gb:AF007217.1 AF007217 thyroid hormone receptor interactor 11 TRIP11 9321 NM_004239 /// XM_005268213 /// XM_005268214 /// XM_005268215 /// XM_006720321 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209779_at AF255792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF255792.1 /DEF=Homo sapiens DC30 mRNA, complete cds. /FEA=mRNA /PROD=DC30 /DB_XREF=gi:12005826 /UG=Hs.124813 Homo sapiens DC30 mRNA, complete cds /FL=gb:AF255792.1 AF255792 LLP homolog, long-term synaptic facilitation (Aplysia) LLPH 84298 NM_032338 0044822 // poly(A) RNA binding // inferred from direct assay 209780_at AL136883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136883.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D166 (from clone DKFZp434D166); complete cds. /FEA=mRNA /GEN=DKFZp434D166 /PROD=hypothetical protein /DB_XREF=gi:12053266 /UG=Hs.128653 hypothetical protein DKFZp564F013 /FL=gb:AL136883.1 AL136883 putative homeodomain transcription factor 2 PHTF2 57157 NM_001127357 /// NM_001127358 /// NM_001127359 /// NM_001127360 /// NM_020432 /// XM_005250508 /// XM_005250509 /// XM_006716063 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 209781_s_at AF069681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF069681.1 /DEF=Homo sapiens T-Star (T-Star) mRNA, complete cds. /FEA=mRNA /GEN=T-Star /PROD=T-Star /DB_XREF=gi:3273831 /UG=Hs.13565 Sam68-like phosphotyrosine protein, T-STAR /FL=gb:AF069681.1 gb:AF051321.1 gb:NM_006558.1 AF069681 KH domain containing, RNA binding, signal transduction associated 3 KHDRBS3 10656 NM_006558 /// XM_005250757 /// XM_005250758 /// XR_242372 /// XR_242374 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209782_s_at U79283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79283.1 /DEF=Human albumin D-box binding protein mRNA, complete cds. /FEA=mRNA /PROD=albumin D-box binding protein /DB_XREF=gi:1710256 /UG=Hs.155402 D site of albumin promoter (albumin D-box) binding protein /FL=gb:U79283.1 gb:NM_001352.1 gb:D28468.1 gb:U06936.1 U79283 D site of albumin promoter (albumin D-box) binding protein DBP 1628 NM_001352 /// XR_243907 0001568 // blood vessel development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006669 // sphinganine-1-phosphate biosynthetic process // non-traceable author statement /// 0006670 // sphingosine metabolic process // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0046834 // lipid phosphorylation // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // non-traceable author statement /// 0017050 // D-erythro-sphingosine kinase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209783_at D28468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28468.1 /DEF=Human mRNA for DNA-binding protein TAXREB302, complete cds. /FEA=mRNA /PROD=TAXREB302 /DB_XREF=gi:460704 /UG=Hs.155402 D site of albumin promoter (albumin D-box) binding protein /FL=gb:U79283.1 gb:NM_001352.1 gb:D28468.1 gb:U06936.1 D28468 D site of albumin promoter (albumin D-box) binding protein DBP 1628 NM_001352 /// XR_243907 0001568 // blood vessel development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006669 // sphinganine-1-phosphate biosynthetic process // non-traceable author statement /// 0006670 // sphingosine metabolic process // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0046834 // lipid phosphorylation // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // non-traceable author statement /// 0017050 // D-erythro-sphingosine kinase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209784_s_at AF029778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029778.1 /DEF=Homo sapiens Jagged2 (JAG2) mRNA, complete cds. /FEA=mRNA /GEN=JAG2 /PROD=Jagged2 /DB_XREF=gi:2605944 /UG=Hs.166154 jagged 2 /FL=gb:AF003521.1 gb:AF020201.1 gb:AF029778.1 gb:NM_002226.1 AF029778 jagged 2 JAG2 3714 NM_002226 /// NM_145159 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern /// 0009912 // auditory receptor cell fate commitment // inferred from sequence or structural similarity /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from direct assay /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from direct assay /// 0030334 // regulation of cell migration // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042492 // gamma-delta T cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from direct assay /// 1990134 // epithelial cell apoptotic process involved in palatal shelf morphogenesis // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005112 // Notch binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 209785_s_at AF065214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF065214.1 /DEF=Homo sapiens cytosolic phospholipase A2 gamma (cPLA2 gamma) mRNA, complete cds. /FEA=mRNA /GEN=cPLA2 gamma /PROD=cytosolic phospholipase A2 gamma /DB_XREF=gi:3811344 /UG=Hs.18858 phospholipase A2, group IVC (cytosolic, calcium-independent) /FL=gb:AF058921.1 gb:AF065214.1 gb:NM_003706.1 AF065214 phospholipase A2, group IVC (cytosolic, calcium-independent) PLA2G4C 8605 NM_001159322 /// NM_001159323 /// NM_003706 /// XM_006723451 /// XM_006723452 /// XM_006723453 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0007567 // parturition // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046475 // glycerophospholipid catabolic process // inferred from direct assay 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0004620 // phospholipase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005543 // phospholipid binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from direct assay 209786_at BC001282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001282.1 /DEF=Homo sapiens, high-mobility group (nonhistone chromosomal) protein 17-like 3, clone MGC:5145, mRNA, complete cds. /FEA=mRNA /PROD=high-mobility group (nonhistone chromosomal)protein 17-like 3 /DB_XREF=gi:12654876 /UG=Hs.236774 high-mobility group (nonhistone chromosomal) protein 17-like 3 /FL=gb:BC001282.1 BC001282 high mobility group nucleosomal binding domain 4 HMGN4 10473 NM_006353 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 209787_s_at BC001282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001282.1 /DEF=Homo sapiens, high-mobility group (nonhistone chromosomal) protein 17-like 3, clone MGC:5145, mRNA, complete cds. /FEA=mRNA /PROD=high-mobility group (nonhistone chromosomal)protein 17-like 3 /DB_XREF=gi:12654876 /UG=Hs.236774 high-mobility group (nonhistone chromosomal) protein 17-like 3 /FL=gb:BC001282.1 BC001282 high mobility group nucleosomal binding domain 4 HMGN4 10473 NM_006353 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 209788_s_at AF183569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF183569.1 /DEF=Homo sapiens aminopeptidase PILS (APPILS) mRNA, complete cds. /FEA=mRNA /GEN=APPILS /PROD=aminopeptidase PILS /DB_XREF=gi:6642986 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator /FL=gb:AF183569.1 gb:AF222340.1 gb:NM_016442.1 AF183569 endoplasmic reticulum aminopeptidase 1 ERAP1 51752 NM_001040458 /// NM_001198541 /// NM_016442 /// XM_005272015 /// XM_005272016 0001525 // angiogenesis // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009617 // response to bacterium // inferred from expression pattern /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // non-traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement /// 0045088 // regulation of innate immune response // non-traceable author statement /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209789_at BF939649 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939649 /FEA=EST /DB_XREF=gi:12357060 /DB_XREF=est:nac79b04.x1 /CLONE=IMAGE:3440574 /UG=Hs.24907 coronin, actin-binding protein, 2B /FL=gb:AB010098.1 BF939649 coronin, actin binding protein, 2B CORO2B 10391 NM_001190456 /// NM_001190457 /// NM_006091 /// XM_005254124 /// XM_005254125 0030036 // actin cytoskeleton organization // not recorded /// 0030036 // actin cytoskeleton organization // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // not recorded /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // not recorded 209790_s_at BC000305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000305.1 /DEF=Homo sapiens, caspase 6, apoptosis-related cysteine protease, clone MGC:8388, mRNA, complete cds. /FEA=mRNA /PROD=caspase 6, apoptosis-related cysteine protease /DB_XREF=gi:12653078 /UG=Hs.3280 caspase 6, apoptosis-related cysteine protease /FL=gb:BC000305.1 gb:BC004460.1 gb:NM_001226.1 gb:U20536.1 BC000305 caspase 6, apoptosis-related cysteine peptidase CASP6 839 NM_001226 /// NM_032992 /// XM_005263271 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 209791_at AL049569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049569 /DEF=Human DNA sequence from clone RP1-37C10 on chromosome 1p35.2-35.21. Contains the gene for the ortholog of mouse and rat PDI (protein-arginine deiminase (KIAA0994, EC 3.5.3.15, peptidylarginine deiminase)), the SDHB gene for succinate dehydrogenase... /FEA=mRNA_4 /DB_XREF=gi:5263031 /UG=Hs.33455 peptidyl arginine deiminase, type II /FL=gb:AB030176.1 AL049569 peptidyl arginine deiminase, type II PADI2 11240 NM_007365 0006464 // cellular protein modification process // inferred from electronic annotation /// 0010848 // regulation of chromatin disassembly // inferred from direct assay /// 0018101 // protein citrullination // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0036413 // histone H3-R26 citrullination // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from mutant phenotype /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from direct assay /// 1901624 // negative regulation of lymphocyte chemotaxis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004668 // protein-arginine deiminase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from physical interaction 209792_s_at BC002710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002710.1 /DEF=Homo sapiens, kallikrein 10, clone MGC:3667, mRNA, complete cds. /FEA=mRNA /PROD=kallikrein 10 /DB_XREF=gi:12803744 /UG=Hs.69423 kallikrein 10 /FL=gb:BC002710.1 BC002710 kallikrein-related peptidase 10 KLK10 5655 NM_001077500 /// NM_002776 /// NM_145888 /// XM_005259061 /// XM_005259062 /// XM_006723287 /// XM_006723288 /// XM_006723289 0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 209793_at AL567302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567302 /FEA=EST /DB_XREF=gi:12920523 /DB_XREF=est:AL567302 /CLONE=CS0DF027YK04 (3 prime) /UG=Hs.7117 glutamate receptor, ionotropic, AMPA 1 /FL=gb:M81886.1 gb:NM_000827.2 AL567302 glutamate receptor, ionotropic, AMPA 1 GRIA1 2890 NM_000827 /// NM_001114183 /// NM_001258019 /// NM_001258020 /// NM_001258021 /// NM_001258022 /// NM_001258023 /// NR_047578 /// XR_427776 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0008328 // ionotropic glutamate receptor complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0044309 // neuron spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // traceable author statement /// 0015277 // kainate selective glutamate receptor activity // traceable author statement /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 209794_at AB007871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007871.1 /DEF=Homo sapiens KIAA0411 mRNA, complete cds. /FEA=mRNA /GEN=KIAA0411 /DB_XREF=gi:2887442 /UG=Hs.7977 KIAA0411 gene product /FL=gb:AB007871.1 AB007871 SLIT-ROBO Rho GTPase activating protein 3 SRGAP3 9901 NM_001033116 /// NM_001033117 /// NM_014850 /// XM_005265622 /// XM_006713433 /// XR_427300 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209795_at L07555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L07555.1 /DEF=Homo sapiens early activation antigen CD69 mRNA, complete cds. /FEA=mRNA /PROD=early activation antigen CD69 /DB_XREF=gi:291897 /UG=Hs.82401 CD69 antigen (p60, early T-cell activation antigen) /FL=gb:L07555.1 gb:NM_001781.1 L07555 CD69 molecule CD69 969 NM_001781 /// NR_026671 /// NR_026672 0007165 // signal transduction // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 209796_s_at BC001027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001027.1 /DEF=Homo sapiens, transmembrane protein 4, clone MGC:1545, mRNA, complete cds. /FEA=mRNA /PROD=transmembrane protein 4 /DB_XREF=gi:12654402 /UG=Hs.8752 transmembrane protein 4 /FL=gb:BC001027.1 gb:AF186113.1 BC001027 canopy FGF signaling regulator 2 CNPY2 10330 NM_001190991 /// NM_014255 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 209797_at BC001027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001027.1 /DEF=Homo sapiens, transmembrane protein 4, clone MGC:1545, mRNA, complete cds. /FEA=mRNA /PROD=transmembrane protein 4 /DB_XREF=gi:12654402 /UG=Hs.8752 transmembrane protein 4 /FL=gb:BC001027.1 gb:AF186113.1 BC001027 canopy FGF signaling regulator 2 CNPY2 10330 NM_001190991 /// NM_014255 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 209798_at D83243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83243.1 /DEF=Human NPAT mRNA, complete cds. /FEA=mRNA /GEN=NPAT /DB_XREF=gi:1304113 /UG=Hs.89385 nuclear protein, ataxia-telangiectasia locus /FL=gb:D83243.1 gb:NM_002519.1 D83243 nuclear protein, ataxia-telangiectasia locus NPAT 4863 NM_002519 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 209799_at AF100763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100763.1 /DEF=Homo sapiens AMP-activated kinase alpha 1 subunit mRNA, complete cds. /FEA=mRNA /PROD=AMP-activated kinase alpha 1 subunit /DB_XREF=gi:5410311 /UG=Hs.9247 protein kinase, AMP-activated, alpha 1 catalytic subunit /FL=gb:AB022017.1 gb:AF100763.1 gb:NM_006251.1 AF100763 protein kinase, AMP-activated, alpha 1 catalytic subunit PRKAA1 5562 NM_006251 /// NM_206907 /// XM_006714481 /// XM_006714482 0000187 // activation of MAPK activity // non-traceable author statement /// 0001666 // response to hypoxia // non-traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from sequence or structural similarity /// 0009631 // cold acclimation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from sequence or structural similarity /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045542 // positive regulation of cholesterol biosynthetic process // non-traceable author statement /// 0045821 // positive regulation of glycolytic process // inferred from sequence or structural similarity /// 0046318 // negative regulation of glucosylceramide biosynthetic process // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from sequence or structural similarity /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071417 // cellular response to organonitrogen compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity /// 2001274 // negative regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004679 // AMP-activated protein kinase activity // inferred from direct assay /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0035174 // histone serine kinase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047322 // [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation /// 0050405 // [acetyl-CoA carboxylase] kinase activity // inferred from electronic annotation 209800_at AF061812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061812.1 /DEF=Homo sapiens keratin 16 (KRT16A) mRNA, complete cds. /FEA=mRNA /GEN=KRT16A /PROD=keratin 16 /DB_XREF=gi:4091878 /UG=Hs.115947 keratin 16 (focal non-epidermolytic palmoplantar keratoderma) /FL=gb:AF061812.1 gb:NM_005557.1 AF061812 keratin 16 KRT16 3868 NM_005557 0007010 // cytoskeleton organization // non-traceable author statement /// 0007568 // aging // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0042633 // hair cycle // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209802_at BC005034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005034.1 /DEF=Homo sapiens, tumor suppressing subtransferable candidate 3, clone MGC:12714, mRNA, complete cds. /FEA=mRNA /PROD=tumor suppressing subtransferable candidate 3 /DB_XREF=gi:13477152 /UG=Hs.154036 tumor suppressing subtransferable candidate 3 /FL=gb:BC005034.1 gb:AF001294.1 gb:AF019953.1 gb:AF035444.1 gb:NM_003311.1 BC005034 pleckstrin homology-like domain, family A, member 2 PHLDA2 7262 NM_003311 0001890 // placenta development // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0070873 // regulation of glycogen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 209803_s_at AF001294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001294.1 /DEF=Homo sapiens IPL (IPL) mRNA, complete cds. /FEA=mRNA /GEN=IPL /PROD=IPL /DB_XREF=gi:2150049 /UG=Hs.154036 tumor suppressing subtransferable candidate 3 /FL=gb:BC005034.1 gb:AF001294.1 gb:AF019953.1 gb:AF035444.1 gb:NM_003311.1 AF001294 pleckstrin homology-like domain, family A, member 2 PHLDA2 7262 NM_003311 0001890 // placenta development // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0070873 // regulation of glycogen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 209804_at D42045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D42045.1 /DEF=Human mRNA for KIAA0086 gene, complete cds. /FEA=mRNA /GEN=KIAA0086 /DB_XREF=gi:577302 /UG=Hs.1560 Homolog of yeast DNA-crosslink repair gene SNM1; KIAA0086 gene product /FL=gb:D42045.1 D42045 DNA cross-link repair 1A DCLRE1A 9937 NM_001271816 /// NM_014881 /// XM_006718090 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 209805_at U14658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U14658.1 /DEF=Human DNA mismatch repair gene homologue (hPMS2) mRNA, complete cds. /FEA=mRNA /GEN=hPMS2 /DB_XREF=gi:557469 /UG=Hs.177548 postmeiotic segregation increased (S. cerevisiae) 2 /FL=gb:NM_000535.2 gb:U14658.1 U14658 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) /// PMS2 C-terminal like pseudogene PMS2 /// PMS2CL 5395 /// 441194 NM_000535 /// NR_002217 /// NR_003085 /// XM_006715742 /// XM_006715743 /// XM_006715744 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0032300 // mismatch repair complex // /// 0032389 // MutLalpha complex // not recorded 0003677 // DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032138 // single base insertion or deletion binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay 209806_at BC000893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000893.1 /DEF=Homo sapiens, H2B histone family, member A, clone MGC:5132, mRNA, complete cds. /FEA=mRNA /PROD=H2B histone family, member A /DB_XREF=gi:12654150 /UG=Hs.247817 H2B histone family, member A /FL=gb:BC000893.1 BC000893 histone cluster 1, H2bk HIST1H2BK 85236 NM_080593 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209807_s_at U18759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18759.1 /DEF=Human nuclear factor I (NFI) mRNA, clone AT1, complete cds. /FEA=mRNA /GEN=NFI /PROD=nuclear factor I /DB_XREF=gi:619725 /UG=Hs.35841 nuclear factor IX (CCAAT-binding transcription factor) /FL=gb:NM_002501.1 gb:L31881.1 gb:U18759.1 U18759 nuclear factor I/X (CCAAT-binding transcription factor) NFIX 4784 NM_001271043 /// NM_001271044 /// NM_002501 /// XM_005259917 /// XM_005259918 /// XM_005259919 /// XM_005259920 /// XM_005259921 /// XM_005259922 /// XM_006722760 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048708 // astrocyte differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement 209808_x_at AW193656 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW193656 /FEA=EST /DB_XREF=gi:6472355 /DB_XREF=est:xm29a04.x1 /CLONE=IMAGE:2685582 /UG=Hs.46700 inhibitor of growth 1 family, member 1 /FL=gb:AB024402.1 gb:AB031269.1 gb:AF181849.1 AW193656 inhibitor of growth family, member 1 ING1 3621 NM_001267728 /// NM_005537 /// NM_198217 /// NM_198218 /// NM_198219 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209810_at J02761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02761.1 /DEF=Human pulmonary surfactant-associated protein B (SP-B) mRNA, complete cds. /FEA=mRNA /GEN=SFTP3 /PROD=pulmonary surfactant-associated protein SP-B /DB_XREF=gi:190673 /UG=Hs.76305 surfactant, pulmonary-associated protein B /FL=gb:J02761.1 gb:NM_000542.1 J02761 surfactant protein B SFTPB 6439 NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation 209811_at BC002427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002427.1 /DEF=Homo sapiens, Similar to caspase 2, clone MGC:2181, mRNA, complete cds. /FEA=mRNA /PROD=Similar to caspase 2 /DB_XREF=gi:12803232 /UG=Hs.108131 caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) /FL=gb:BC002427.1 gb:U13021.1 BC002427 caspase 2, apoptosis-related cysteine peptidase CASP2 835 NM_001224 /// NM_032982 /// NM_032983 0001554 // luteolysis // inferred from electronic annotation /// 0003407 // neural retina development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 209812_x_at U13021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13021.1 /DEF=Human positive regulator of programmed cell death ICH-1L (Ich-1) mRNA, complete cds. /FEA=mRNA /GEN=Ich-1 /PROD=ICH-1L /DB_XREF=gi:537291 /UG=Hs.108131 caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) /FL=gb:BC002427.1 gb:U13021.1 U13021 caspase 2, apoptosis-related cysteine peptidase CASP2 835 NM_001224 /// NM_032982 /// NM_032983 0001554 // luteolysis // inferred from electronic annotation /// 0003407 // neural retina development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 209813_x_at M16768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M16768.1 /DEF=Human T-cell receptor gamma chain VJCI-CII-CIII region mRNA, complete cds. /FEA=mRNA /GEN=TCRG /DB_XREF=gi:339399 /UG=Hs.112259 T cell receptor gamma locus /FL=gb:M16768.1 gb:AF151103.1 M16768 TCR gamma alternate reading frame protein /// T cell receptor gamma constant 2 /// T cell receptor gamma variable 9 TARP /// TRGC2 /// TRGV9 6967 /// 6983 /// 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 209814_at BC004421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004421.1 /DEF=Homo sapiens, nucleolar cysteine-rich protein, clone MGC:1452, mRNA, complete cds. /FEA=mRNA /PROD=nucleolar cysteine-rich protein /DB_XREF=gi:13325205 /UG=Hs.120766 nucleolar cysteine-rich protein /FL=gb:BC004421.1 gb:NM_014487.2 BC004421 zinc finger protein 330 ZNF330 27309 NM_001292002 /// NM_014487 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement 209815_at BG054916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG054916 /FEA=EST /DB_XREF=gi:12512119 /DB_XREF=est:nac92b02.x1 /CLONE=IMAGE:3441723 /UG=Hs.159526 patched (Drosophila) homolog /FL=gb:U43148.1 BG054916 patched 1 PTCH1 5727 NM_000264 /// NM_001083602 /// NM_001083603 /// NM_001083604 /// NM_001083605 /// NM_001083606 /// NM_001083607 /// XM_005252102 /// XR_242599 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021532 // neural tube patterning // inferred from mutant phenotype /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021997 // neural plate axis specification // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061005 // cell differentiation involved in kidney development // inferred from electronic annotation /// 0061053 // somite development // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from expression pattern /// 0072203 // cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0044294 // dendritic growth cone // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072372 // primary cilium // inferred from electronic annotation 0005113 // patched binding // inferred from electronic annotation /// 0005119 // smoothened binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0030332 // cyclin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0097108 // hedgehog family protein binding // inferred from physical interaction 209816_at AL044175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044175 /FEA=EST /DB_XREF=gi:5935953 /DB_XREF=est:DKFZp434P0428_s1 /CLONE=DKFZp434P0428 /UG=Hs.159526 patched (Drosophila) homolog /FL=gb:U43148.1 AL044175 patched 1 PTCH1 5727 NM_000264 /// NM_001083602 /// NM_001083603 /// NM_001083604 /// NM_001083605 /// NM_001083606 /// NM_001083607 /// XM_005252102 /// XR_242599 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021532 // neural tube patterning // inferred from mutant phenotype /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021997 // neural plate axis specification // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061005 // cell differentiation involved in kidney development // inferred from electronic annotation /// 0061053 // somite development // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from expression pattern /// 0072203 // cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0044294 // dendritic growth cone // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072372 // primary cilium // inferred from electronic annotation 0005113 // patched binding // inferred from electronic annotation /// 0005119 // smoothened binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0030332 // cyclin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0097108 // hedgehog family protein binding // inferred from physical interaction 209817_at M29550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29550.1 /DEF=Human calcineurin A1 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180706 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:M29550.1 M29550 protein phosphatase 3, catalytic subunit, beta isozyme PPP3CB 5532 NM_001142353 /// NM_001142354 /// NM_001289968 /// NM_001289969 /// NM_021132 /// XM_005269944 /// XM_005269945 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007612 // learning // traceable author statement /// 0007613 // memory // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035176 // social behavior // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0048675 // axon extension // traceable author statement /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005955 // calcineurin complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from sequence or structural similarity /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 209818_s_at AF241831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241831.1 /DEF=Homo sapiens intracellular hyaluronan-binding protein mRNA, complete cds. /FEA=mRNA /PROD=intracellular hyaluronan-binding protein /DB_XREF=gi:7417371 /UG=Hs.301839 intracellular antigen detected by monoclonal antibody Ki-1; intracellular hyaluronan-binding protein /FL=gb:AF241831.1 AF241831 hyaluronan binding protein 4 HABP4 22927 NM_014282 /// XM_005251812 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 209819_at AF241831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241831.1 /DEF=Homo sapiens intracellular hyaluronan-binding protein mRNA, complete cds. /FEA=mRNA /PROD=intracellular hyaluronan-binding protein /DB_XREF=gi:7417371 /UG=Hs.301839 intracellular antigen detected by monoclonal antibody Ki-1; intracellular hyaluronan-binding protein /FL=gb:AF241831.1 AF241831 hyaluronan binding protein 4 HABP4 22927 NM_014282 /// XM_005251812 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030017 // sarcomere // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 209820_s_at BC002361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002361.1 /DEF=Homo sapiens, Similar to transducin (beta)-like 3, clone MGC:8613, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transducin (beta)-like 3 /DB_XREF=gi:12803114 /UG=Hs.322490 Homo sapiens, Similar to transducin (beta)-like 3, clone MGC:8613, mRNA, complete cds /FL=gb:BC002361.1 BC002361 transducin (beta)-like 3 TBL3 10607 NM_006453 0006364 // rRNA processing // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // traceable author statement /// 0010310 // regulation of hydrogen peroxide metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0060263 // regulation of respiratory burst // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from direct assay 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from electronic annotation /// 0016176 // superoxide-generating NADPH oxidase activator activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209821_at AB024518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB024518.1 /DEF=Homo sapiens mRNA for DVS27-related protein, complete cds. /FEA=mRNA /GEN=DVS27 /PROD=DVS27-related protein /DB_XREF=gi:4520327 /UG=Hs.58589 glycogenin 2 /FL=gb:AB024518.1 AB024518 interleukin 33 IL33 90865 NM_001199640 /// NM_001199641 /// NM_033439 /// XM_005251626 /// XM_005251627 0002686 // negative regulation of leukocyte migration // inferred from electronic annotation /// 0002826 // negative regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0002830 // positive regulation of type 2 immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032736 // positive regulation of interleukin-13 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051024 // positive regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051025 // negative regulation of immunoglobulin secretion // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209822_s_at L22431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L22431.1 /DEF=Human very low density lipoprotein receptor, complete cds. /FEA=mRNA /PROD=very low density lipoprotein receptor /DB_XREF=gi:437386 /UG=Hs.73729 very low density lipoprotein receptor /FL=gb:D16493.1 gb:L22431.1 gb:NM_003383.1 L22431 very low density lipoprotein receptor VLDLR 7436 NM_001018056 /// NM_003383 /// XM_006716864 /// XM_006716865 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007613 // memory // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0021517 // ventral spinal cord development // inferred from electronic annotation /// 0034436 // glycoprotein transport // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0038026 // reelin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from sequence or structural similarity /// 0034189 // very-low-density lipoprotein particle binding // inferred from direct assay /// 0034437 // glycoprotein transporter activity // inferred from direct assay /// 0038025 // reelin receptor activity // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 209823_x_at M17955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M17955.1 /DEF=Human MHC class II HLA-DQ-beta mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:188178 /UG=Hs.73931 major histocompatibility complex, class II, DQ beta 1 /FL=gb:M33907.1 gb:M17955.1 gb:M17563.1 gb:M26042.1 gb:M20432.1 gb:M16996.1 M17955 major histocompatibility complex, class II, DQ beta 1 /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// LOC101060835 3119 /// 101060835 NM_001243961 /// NM_001243962 /// NM_002123 /// XM_003960955 /// XM_005276082 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 209824_s_at AB000812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000812.1 /DEF=Homo sapiens mRNA for BMAL1b, complete cds. /FEA=mRNA /PROD=BMAL1b /DB_XREF=gi:2094734 /UG=Hs.74515 aryl hydrocarbon receptor nuclear translocator-like /FL=gb:AB000812.1 gb:AF044288.1 AB000812 aryl hydrocarbon receptor nuclear translocator-like ARNTL 406 NM_001030272 /// NM_001030273 /// NM_001178 /// XM_005252928 /// XM_005252929 /// XM_005252930 /// XM_006718233 /// XM_006718234 /// XM_006718235 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // traceable author statement /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090403 // oxidative stress-induced premature senescence // inferred from sequence or structural similarity /// 2000074 // regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity /// 2000772 // regulation of cellular senescence // inferred from sequence or structural similarity /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017162 // aryl hydrocarbon receptor binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay 209825_s_at BC002906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002906.1 /DEF=Homo sapiens, Similar to uridine monophosphate kinase, clone MGC:10318, mRNA, complete cds. /FEA=mRNA /PROD=Similar to uridine monophosphate kinase /DB_XREF=gi:12804106 /UG=Hs.75939 uridine monophosphate kinase /FL=gb:BC002906.1 gb:AF236637.1 BC002906 microRNA 3658 /// uridine-cytidine kinase 2 MIR3658 /// UCK2 7371 /// 100500832 NM_012474 /// NR_037431 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044206 // UMP salvage // inferred from electronic annotation /// 0044211 // CTP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004140 // dephospho-CoA kinase activity // inferred from electronic annotation /// 0004849 // uridine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded 209826_at AF020544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020544.1 /DEF=Homo sapiens inactive palmitoyl-protein thioesterase-2i (PPT2) mRNA, complete cds. /FEA=mRNA /GEN=PPT2 /PROD=inactive palmitoyl-protein thioesterase-2i /DB_XREF=gi:2501962 /UG=Hs.81737 palmitoyl-protein thioesterase 2 /FL=gb:AF020544.1 AF020544 EGF-like-domain, multiple 8 /// palmitoyl-protein thioesterase 2 /// PPT2-EGFL8 readthrough (NMD candidate) EGFL8 /// PPT2 /// PPT2-EGFL8 9374 /// 80864 /// 100532746 NM_001204103 /// NM_005155 /// NM_030652 /// NM_138717 /// NM_138934 /// NR_037860 /// NR_037861 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008474 // palmitoyl-(protein) hydrolase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // non-traceable author statement 209827_s_at NM_004513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004513.1 /DEF=Homo sapiens interleukin 16 (lymphocyte chemoattractant factor) (IL16), mRNA. /FEA=CDS /GEN=IL16 /PROD=interleukin 16 /DB_XREF=gi:4758595 /UG=Hs.82127 interleukin 16 (lymphocyte chemoattractant factor) /FL=gb:S81601.1 gb:U82972.1 gb:AF053412.1 gb:M90391.1 gb:NM_004513.1 NM_004513 interleukin 16 IL16 3603 NM_001172128 /// NM_004513 /// NM_172217 /// XM_005254342 /// XM_005254343 /// XM_005254344 /// XM_005254345 /// XM_005254346 /// XR_429452 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 209828_s_at M90391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90391.1 /DEF=Homo sapiens putative IL-16 protein precursor, mRNA, complete cds. /FEA=mRNA /PROD=putative IL-16 protein precursor /DB_XREF=gi:4153827 /UG=Hs.82127 interleukin 16 (lymphocyte chemoattractant factor) /FL=gb:S81601.1 gb:U82972.1 gb:AF053412.1 gb:M90391.1 gb:NM_004513.1 M90391 interleukin 16 IL16 3603 NM_001172128 /// NM_004513 /// NM_172217 /// XM_005254342 /// XM_005254343 /// XM_005254344 /// XM_005254345 /// XM_005254346 /// XR_429452 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 209829_at AB002384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002384.1 /DEF=Human mRNA for KIAA0386 gene, complete cds. /FEA=mRNA /GEN=KIAA0386 /DB_XREF=gi:2224712 /UG=Hs.101359 chromosome 6 open reading frame 32 /FL=gb:AB002384.1 AB002384 family with sequence similarity 65, member B FAM65B 9750 NM_001286445 /// NM_001286446 /// NM_001286447 /// NM_014722 /// NM_015864 /// XM_006715275 /// XM_006715276 /// XM_006715277 /// XM_006715278 /// XM_006715279 /// XM_006715280 /// XM_006715281 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 209830_s_at AF035771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035771.1 /DEF=Homo sapiens Na+H+ exchanger regulatory factor 2 (NHERF-2) mRNA, complete cds. /FEA=mRNA /GEN=NHERF-2 /PROD=Na+H+ exchanger regulatory factor 2 /DB_XREF=gi:2665825 /UG=Hs.101813 solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 2 /FL=gb:AF004900.1 gb:AF035771.1 gb:NM_004785.1 AF035771 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 SLC9A3R2 9351 NM_001130012 /// NM_001252073 /// NM_001252075 /// NM_001252076 /// NM_004785 /// XM_005255702 /// XM_005255703 /// XM_006720981 0006461 // protein complex assembly // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction 209831_x_at AB004574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB004574.1 /DEF=Homo sapiens mRNA for deoxyribonuclease II, complete cds. /FEA=mRNA /GEN=DNASE2 /PROD=deoxyribonuclease II /DB_XREF=gi:3184394 /UG=Hs.118243 deoxyribonuclease II, lysosomal /FL=gb:AF045937.1 gb:AF047016.1 gb:AB004574.1 gb:AF060222.1 gb:NM_001375.1 AB004574 deoxyribonuclease II, lysosomal DNASE2 1777 NM_001375 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // inferred from electronic annotation /// 0004531 // deoxyribonuclease II activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation 209832_s_at AF321125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF321125.1 /DEF=Homo sapiens DNA replication factor (CDT1) mRNA, complete cds. /FEA=mRNA /GEN=CDT1 /PROD=DNA replication factor /DB_XREF=gi:12007404 /UG=Hs.122908 DNA replication factor /FL=gb:AF321125.1 AF321125 chromatin licensing and DNA replication factor 1 CDT1 81620 NM_030928 0000076 // DNA replication checkpoint // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // inferred from direct assay /// 0033262 // regulation of nuclear cell cycle DNA replication // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 209833_at U79115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79115.1 /DEF=Human death adaptor molecule RAIDD (RAIDD) mRNA, complete cds. /FEA=mRNA /GEN=RAIDD /PROD=death adaptor molecule RAIDD /DB_XREF=gi:1785556 /UG=Hs.155566 CASP2 and RIPK1 domain containing adaptor with death domain /FL=gb:U79115.1 gb:U84388.1 gb:NM_003805.1 U79115 CASP2 and RIPK1 domain containing adaptor with death domain CRADD 8738 NM_003805 /// XM_005269211 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred by curator /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction 209834_at AB017915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017915.1 /DEF=Homo sapiens mRNA for chondroitin 6-sulfotransferase, complete cds. /FEA=mRNA /PROD=chondroitin 6-sulfotransferase /DB_XREF=gi:4115403 /UG=Hs.158304 carbohydrate (chondroitin 6keratan) sulfotransferase 3 /FL=gb:AB017915.1 AB017915 carbohydrate (chondroitin 6) sulfotransferase 3 CHST3 9469 NM_004273 /// XM_006718075 0005975 // carbohydrate metabolic process // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0008459 // chondroitin 6-sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0050698 // proteoglycan sulfotransferase activity // inferred from electronic annotation 209835_x_at BC004372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004372.1 /DEF=Homo sapiens, Similar to CD44 antigen (homing function and Indian blood group system), clone MGC:10468, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CD44 antigen (homing function andIndian blood group system) /DB_XREF=gi:13325117 /UG=Hs.169610 CD44 antigen (homing function and Indian blood group system) /FL=gb:BC004372.1 BC004372 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 209836_x_at AF060511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF060511.1 /DEF=Homo sapiens clone 016b10 My016 protein mRNA, complete cds. /FEA=mRNA /PROD=My016 protein /DB_XREF=gi:12001971 /UG=Hs.181634 Homo sapiens cDNA: FLJ23602 fis, clone LNG15735 /FL=gb:AF060511.1 AF060511 bolA family member 2 /// bolA family member 2B BOLA2 /// BOLA2B 552900 /// 654483 NM_001031827 /// NM_001031833 /// NM_001039182 0016310 // phosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0016301 // kinase activity // inferred from electronic annotation 209837_at AF155158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155158.1 /DEF=Homo sapiens adaptor-related protein complex AP-4 mu4 subunit mRNA, complete cds. /FEA=mRNA /PROD=adaptor-related protein complex AP-4 mu4subunit /DB_XREF=gi:5442365 /UG=Hs.194703 adaptor-related protein complex 4, mu 1 subunit /FL=gb:AF020796.1 gb:NM_004722.1 gb:AF155158.1 AF155158 adaptor-related protein complex 4, mu 1 subunit AP4M1 9179 NM_004722 /// XM_005250689 /// XM_005250690 /// XM_005250691 /// XM_006716175 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000138 // Golgi trans cisterna // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 209838_at AA496247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA496247 /FEA=EST /DB_XREF=gi:2229568 /DB_XREF=est:zx70h10.s1 /CLONE=IMAGE:796867 /UG=Hs.30212 thyroid receptor interacting protein 15 /FL=gb:AF212227.1 AA496247 COP9 signalosome subunit 2 COPS2 9318 NM_001143887 /// NM_004236 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010388 // cullin deneddylation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209839_at AL136712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136712.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566K013 (from clone DKFZp566K013); complete cds. /FEA=mRNA /GEN=DKFZp566K013 /PROD=hypothetical protein /DB_XREF=gi:12052943 /UG=Hs.33578 KIAA0820 protein /FL=gb:AL136712.1 AL136712 dynamin 3 DNM3 26052 NM_001136127 /// NM_001278252 /// NM_015569 /// XM_005245079 /// XM_005245080 /// XM_005245081 /// XM_005245082 /// XM_005245084 /// XM_006711268 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209840_s_at AI221950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI221950 /FEA=EST /DB_XREF=gi:3804153 /DB_XREF=est:qh01b02.x1 /CLONE=IMAGE:1843371 /UG=Hs.3781 similar to murine leucine-rich repeat protein /FL=gb:AL442092.1 AI221950 leucine rich repeat neuronal 3 LRRN3 54674 NM_001099658 /// NM_001099660 /// NM_018334 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 209841_s_at AL442092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL442092.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761K2424 (from clone DKFZp761K2424); complete cds. /FEA=mRNA /GEN=DKFZp761K2424 /PROD=hypothetical protein /DB_XREF=gi:10241766 /UG=Hs.3781 similar to murine leucine-rich repeat protein /FL=gb:AL442092.1 AL442092 leucine rich repeat neuronal 3 LRRN3 54674 NM_001099658 /// NM_001099660 /// NM_018334 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 209842_at AI367319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI367319 /FEA=EST /DB_XREF=gi:4137064 /DB_XREF=est:qq20h08.x1 /CLONE=IMAGE:1933119 /UG=Hs.44317 SRY (sex determining region Y)-box 10 /FL=gb:BC002824.1 gb:NM_006941.1 AI367319 SRY (sex determining region Y)-box 10 SOX10 6663 NM_006941 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014015 // positive regulation of gliogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031315 // extrinsic component of mitochondrial outer membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 209843_s_at BC002824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002824.1 /DEF=Homo sapiens, SRY (sex determining region Y)-box 10, clone MGC:3510, mRNA, complete cds. /FEA=mRNA /PROD=SRY (sex determining region Y)-box 10 /DB_XREF=gi:12803952 /UG=Hs.44317 SRY (sex determining region Y)-box 10 /FL=gb:BC002824.1 gb:NM_006941.1 BC002824 SRY (sex determining region Y)-box 10 SOX10 6663 NM_006941 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014015 // positive regulation of gliogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031315 // extrinsic component of mitochondrial outer membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 209844_at U57052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U57052.1 /DEF=Human Hoxb-13 mRNA, complete cds. /FEA=mRNA /PROD=Hoxb-13 /DB_XREF=gi:1519039 /UG=Hs.66731 homeo box B13 /FL=gb:U57052.1 gb:U81599.1 U57052 homeobox B13 HOXB13 10481 NM_006361 0001525 // angiogenesis // inferred from expression pattern /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209845_at AF117233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF117233.1 /DEF=Homo sapiens znf-xp protein mRNA, complete cds. /FEA=mRNA /PROD=znf-xp protein /DB_XREF=gi:6563239 /UG=Hs.7838 makorin, ring finger protein, 1 /FL=gb:AF117233.1 AF117233 makorin ring finger protein 1 MKRN1 23608 NM_001145125 /// NM_001291663 /// NM_013446 /// NR_117084 0000209 // protein polyubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209846_s_at BC002832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002832.1 /DEF=Homo sapiens, Similar to butyrophilin, subfamily 3, member A2, clone MGC:3790, mRNA, complete cds. /FEA=mRNA /PROD=Similar to butyrophilin, subfamily 3, member A2 /DB_XREF=gi:12803966 /UG=Hs.87497 butyrophilin, subfamily 3, member A2 /FL=gb:BC002832.1 gb:U90144.1 gb:U90546.1 gb:NM_007047.1 BC002832 butyrophilin, subfamily 3, member A2 BTN3A2 11118 NM_001197246 /// NM_001197247 /// NM_001197248 /// NM_001197249 /// NM_007047 /// XM_005248827 /// XM_005248831 /// XM_005248832 /// XM_006714979 /// XM_006714980 /// XM_006714981 /// XM_006714982 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209847_at U07969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U07969.1 /DEF=Human intestinal peptide-associated transporter HPT-1 mRNA, complete cds. /FEA=mRNA /PROD=intestinal peptide-associated transporter HPT-1 /DB_XREF=gi:483391 /UG=Hs.89436 cadherin 17, LI cadherin (liver-intestine) /FL=gb:NM_004063.1 gb:U07969.1 U07969 cadherin 17, LI cadherin (liver-intestine) CDH17 1015 NM_001144663 /// NM_004063 0006810 // transport // non-traceable author statement /// 0006857 // oligopeptide transport // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0016339 // calcium-dependent cell-cell adhesion // inferred from sequence or structural similarity /// 0035672 // oligopeptide transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005427 // proton-dependent oligopeptide secondary active transmembrane transporter activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209848_s_at U01874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01874.1 /DEF=Human me20m mRNA, complete cds. /FEA=mRNA /PROD=me20m /DB_XREF=gi:494939 /UG=Hs.95972 silver (mouse homolog) like /FL=gb:BC001414.1 gb:U01874.1 gb:NM_006928.1 U01874 premelanosome protein PMEL 6490 NM_001200053 /// NM_001200054 /// NM_006928 /// XM_006719568 /// XM_006719569 0032438 // melanosome organization // inferred from direct assay /// 0042438 // melanin biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209849_s_at AF029669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029669.1 /DEF=Homo sapiens Rad51C (RAD51C) mRNA, complete cds. /FEA=mRNA /GEN=RAD51C /PROD=Rad51C /DB_XREF=gi:2909800 /UG=Hs.11393 RAD51 (S. cerevisiae) homolog C /FL=gb:AF029669.1 AF029669 RAD51 paralog C RAD51C 5889 NM_002876 /// NM_058216 /// NR_103872 /// NR_103873 /// XM_006722001 /// XM_006722002 /// XM_006722003 /// XM_006722004 /// XM_006722005 /// XM_006722006 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006310 // DNA recombination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from sequence or structural similarity /// 0007066 // female meiosis sister chromatid cohesion // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay /// 0033065 // Rad51C-XRCC3 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048476 // Holliday junction resolvase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 209850_s_at BC005406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005406.1 /DEF=Homo sapiens, Cdc42 effector protein 2, clone MGC:5143, mRNA, complete cds. /FEA=mRNA /PROD=Cdc42 effector protein 2 /DB_XREF=gi:13529304 /UG=Hs.12289 Cdc42 effector protein 2 /FL=gb:BC005406.1 gb:AF001436.1 gb:AF098290.1 gb:AF163840.1 gb:NM_006779.1 BC005406 CDC42 effector protein (Rho GTPase binding) 2 CDC42EP2 10435 NM_006779 0007015 // actin filament organization // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0001515 // opioid peptide activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from physical interaction 209851_at AL136745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136745.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D1812 (from clone DKFZp434D1812); complete cds. /FEA=mRNA /GEN=DKFZp434D1812 /PROD=hypothetical protein /DB_XREF=gi:12053006 /UG=Hs.136102 KIAA0853 protein /FL=gb:AL136745.1 AL136745 zinc finger CCCH-type containing 13 ZC3H13 23091 NM_015070 /// XM_005266301 /// XM_005266302 /// XM_005266303 /// XM_005266304 /// XM_005266305 /// XM_005266306 /// XM_005266307 /// XM_005266308 /// XM_005266309 /// XM_005266310 /// XM_005266311 /// XM_005266312 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209852_x_at BC001423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001423.1 /DEF=Homo sapiens, Similar to proteaseome (prosome, macropain) 28 subunit, 3, clone MGC:1394, mRNA, complete cds. /FEA=mRNA /PROD=Similar to proteaseome (prosome, macropain) 28subunit, 3 /DB_XREF=gi:12655138 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:BC001423.1 gb:BC002684.1 BC001423 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 209853_s_at BC002684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002684.1 /DEF=Homo sapiens, proteaseome (prosome, macropain) 28 subunit, 3, clone MGC:3572, mRNA, complete cds. /FEA=mRNA /PROD=proteaseome (prosome, macropain) 28 subunit, 3 /DB_XREF=gi:12803696 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:BC001423.1 gb:BC002684.1 BC002684 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 209854_s_at AA595465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA595465 /FEA=EST /DB_XREF=gi:2410815 /DB_XREF=est:no34e09.s1 /CLONE=IMAGE:1102600 /UG=Hs.181350 kallikrein 2, prostatic /FL=gb:AF188745.1 gb:AF188747.1 AA595465 kallikrein-related peptidase 2 KLK2 3817 NM_001002231 /// NM_001002232 /// NM_001256080 /// NM_005551 /// NR_045762 /// NR_045763 /// XM_006723206 /// XM_006723207 /// XM_006723208 /// XM_006723209 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209855_s_at AF188747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF188747.1 /DEF=Homo sapiens prostrate kallikrein 2 (KLK2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=KLK2 /PROD=prostrate kallikrein 2 /DB_XREF=gi:6425047 /UG=Hs.181350 kallikrein 2, prostatic /FL=gb:AF188745.1 gb:AF188747.1 AF188747 kallikrein-related peptidase 2 KLK2 3817 NM_001002231 /// NM_001002232 /// NM_001256080 /// NM_005551 /// NR_045762 /// NR_045763 /// XM_006723206 /// XM_006723207 /// XM_006723208 /// XM_006723209 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 209856_x_at U31089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31089.1 /DEF=Human Abl binding protein 3 (AblBP3) mRNA, complete cds. /FEA=mRNA /GEN=AblBP3 /PROD=Abl binding protein 3 /DB_XREF=gi:987264 /UG=Hs.256315 abl-interactor 12 (SH3-containing protein) /FL=gb:BC001439.1 gb:U31089.1 U31089 abl-interactor 2 ABI2 10152 NM_001282925 /// NM_001282926 /// NM_001282927 /// NM_001282932 /// NM_005759 /// XM_005246217 /// XM_005246218 /// XM_005246221 /// XM_005246222 /// XM_005246223 /// XM_005246224 /// XM_005246225 /// XM_005246226 /// XM_005246229 /// XM_006712174 /// XM_006712175 /// XM_006712176 /// XM_006712177 /// XM_006712178 /// XM_006712179 /// XM_006712180 /// XM_006712181 /// XM_006712182 /// XM_006712183 /// XM_006712184 /// XM_006712185 /// XM_006712186 0006928 // cellular component movement // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // traceable author statement /// 0019900 // kinase binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 209857_s_at AF245447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF245447.1 /DEF=Homo sapiens sphingosine kinase type 2 isoform mRNA, complete cds. /FEA=mRNA /PROD=sphingosine kinase type 2 isoform /DB_XREF=gi:8248284 /UG=Hs.301305 sphingosine kinase type 2 isoform /FL=gb:AL136701.1 gb:AF245447.1 gb:NM_020126.1 AF245447 sphingosine kinase 2 SPHK2 56848 NM_001204158 /// NM_001204159 /// NM_001204160 /// NM_001243876 /// NM_020126 /// XM_006723290 /// XM_006723291 /// XM_006723292 /// XM_006723293 /// XM_006723294 0001568 // blood vessel development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006669 // sphinganine-1-phosphate biosynthetic process // non-traceable author statement /// 0006670 // sphingosine metabolic process // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0046834 // lipid phosphorylation // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // non-traceable author statement /// 0017050 // D-erythro-sphingosine kinase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209858_x_at BC002877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002877.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ11585, clone MGC:11258, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ11585 /DB_XREF=gi:12804048 /UG=Hs.315367 Homo sapiens, Similar to hypothetical protein FLJ11585, clone MGC:11258, mRNA, complete cds /FL=gb:BC002877.1 BC002877 metallophosphoesterase 1 MPPE1 65258 NM_001242904 /// NM_023075 /// NM_138608 /// NR_040241 /// NR_040242 /// NR_040243 /// XM_006722340 /// XM_006722341 /// XM_006722342 /// XM_006722343 /// XM_006722344 /// XM_006722345 /// XM_006722346 /// XM_006722347 /// XM_006722348 /// XM_006722349 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from sequence or structural similarity 0008081 // phosphoric diester hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 209859_at AF220036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220036.1 /DEF=Homo sapiens tripartite motif protein TRIM9 isoform alpha (TRIM9) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM9 /PROD=tripartite motif protein TRIM9 isoform alpha /DB_XREF=gi:12407402 /UG=Hs.75090 KIAA0282 protein /FL=gb:AF220036.1 gb:AF220037.1 gb:AF220038.1 AF220036 tripartite motif containing 9 TRIM9 114088 NM_015163 /// NM_052978 /// XM_005267301 /// XM_005267302 /// XM_006720017 /// XM_006720018 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035544 // negative regulation of SNARE complex assembly // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209860_s_at J04543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04543.1 /DEF=Human synexin mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:338243 /UG=Hs.78637 annexin A7 /FL=gb:BC002632.1 gb:J04543.1 gb:NM_001156.2 J04543 annexin A7 ANXA7 310 NM_001156 /// NM_004034 /// XM_005269738 /// XM_005269739 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007599 // hemostasis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009992 // cellular water homeostasis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0035176 // social behavior // inferred from expression pattern /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 209861_s_at U13261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13261.1 /DEF=Homo sapiens eIF-2-associated p67 homolog mRNA, complete cds. /FEA=mRNA /PROD=eIF-2-associated p67 homolog /DB_XREF=gi:687242 /UG=Hs.78935 methionine aminopeptidase; eIF-2-associated p67 /FL=gb:U13261.1 U13261 methionyl aminopeptidase 2 METAP2 10988 NM_006838 /// XM_005268583 0006508 // proteolysis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031365 // N-terminal protein amino acid modification // inferred from direct assay /// 0070084 // protein initiator methionine removal // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from electronic annotation 209862_s_at BC001233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001233.1 /DEF=Homo sapiens, Similar to KIAA0092 gene product, clone MGC:4896, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0092 gene product /DB_XREF=gi:12654780 /UG=Hs.134158 Homo sapiens, Similar to KIAA0092 gene product, clone MGC:4896, mRNA, complete cds /FL=gb:BC001233.1 BC001233 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 209863_s_at AF091627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF091627.1 /DEF=Homo sapiens CUSP mRNA, complete cds. /FEA=mRNA /PROD=CUSP /DB_XREF=gi:3644039 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AF091627.1 gb:AF075431.1 gb:AF075433.1 AF091627 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 209864_at AB045118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB045118.1 /DEF=Homo sapiens FRAT2 mRNA, complete cds. /FEA=mRNA /GEN=FRAT2 /PROD=FRAT2 /DB_XREF=gi:13365650 /UG=Hs.140720 GSK-3 binding protein FRAT2 /FL=gb:AB045118.1 AB045118 frequently rearranged in advanced T-cell lymphomas 2 FRAT2 23401 NM_012083 0007275 // multicellular organismal development // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 209865_at BC005136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005136.1 /DEF=Homo sapiens, Similar to solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3, clone MGC:1421, mRNA, complete cds. /FEA=mRNA /PROD=Similar to solute carrier family 35(UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member3 /DB_XREF=gi:13477322 /UG=Hs.159322 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 /FL=gb:BC005136.1 BC005136 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 SLC35A3 23443 NM_001271684 /// NM_001271685 /// NM_012243 /// XM_005270691 /// XM_005270693 /// XM_006710516 /// XM_006710517 0006047 // UDP-N-acetylglucosamine metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015788 // UDP-N-acetylglucosamine transport // inferred from mutant phenotype /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005462 // UDP-N-acetylglucosamine transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209866_s_at R50822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R50822 /FEA=EST /DB_XREF=gi:812724 /DB_XREF=est:yg62c01.s1 /CLONE=IMAGE:37438 /UG=Hs.21917 KIAA0768 protein /FL=gb:AF307080.1 R50822 latrophilin 3 LPHN3 23284 NM_015236 /// XM_006714153 /// XM_006714154 /// XM_006714155 /// XM_006714156 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 209867_s_at AF307080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF307080.1 /DEF=Homo sapiens lectomedin-3 (LEC3) mRNA, complete cds. /FEA=mRNA /GEN=LEC3 /PROD=lectomedin-3 /DB_XREF=gi:11037015 /UG=Hs.21917 KIAA0768 protein /FL=gb:AF307080.1 AF307080 latrophilin 3 LPHN3 23284 NM_015236 /// XM_006714153 /// XM_006714154 /// XM_006714155 /// XM_006714156 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 209868_s_at D28482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28482.1 /DEF=Human scr2 mRNA for RNA binding protein SCR2, complete cds. /FEA=mRNA /GEN=scr2 /PROD=SCR2 /DB_XREF=gi:520588 /UG=Hs.241567 RNA binding motif, single stranded interacting protein 1 /FL=gb:D28482.1 gb:NM_016836.1 gb:NM_016838.1 gb:NM_002897.2 D28482 RNA binding motif, single stranded interacting protein 1 RBMS1 5937 NM_002897 /// NM_016836 /// NM_016839 /// XM_005246737 /// XM_005246738 /// XM_005246739 /// XM_005246740 /// XM_005246741 /// XM_006712671 /// XM_006712672 /// XM_006712673 /// XM_006712674 /// XM_006712675 0006260 // DNA replication // non-traceable author statement /// 0006396 // RNA processing // traceable author statement 0005634 // nucleus // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209869_at AF284095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF284095.1 /DEF=Homo sapiens alpha-2A adrenergic receptor mRNA, complete cds. /FEA=mRNA /PROD=alpha-2A adrenergic receptor /DB_XREF=gi:13447750 /UG=Hs.249159 adrenergic, alpha-2A-, receptor /FL=gb:AF284095.1 gb:NM_000681.1 AF284095 adrenoceptor alpha 2A ADRA2A 150 NM_000681 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // non-traceable author statement /// 0010700 // negative regulation of norepinephrine secretion // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032811 // negative regulation of epinephrine secretion // non-traceable author statement /// 0032870 // cellular response to hormone stimulus // inferred from genetic interaction /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0042596 // fear response // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred by curator /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050892 // intestinal absorption // traceable author statement /// 0050955 // thermoception // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from genetic interaction /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from sequence or structural similarity /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype /// 0070473 // negative regulation of uterine smooth muscle contraction // inferred from electronic annotation /// 0071878 // negative regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0071881 // adenylate cyclase-inhibiting adrenergic receptor signaling pathway // inferred from direct assay /// 0071882 // phospholipase C-activating adrenergic receptor signaling pathway // inferred from direct assay /// 0071883 // activation of MAPK activity by adrenergic receptor signaling pathway // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 1901020 // negative regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // traceable author statement /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004938 // alpha2-adrenergic receptor activity // inferred from direct assay /// 0004938 // alpha2-adrenergic receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031692 // alpha-1B adrenergic receptor binding // inferred from sequence or structural similarity /// 0031696 // alpha-2C adrenergic receptor binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0032795 // heterotrimeric G-protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0051379 // epinephrine binding // inferred from direct assay /// 0051380 // norepinephrine binding // inferred from direct assay 209870_s_at AW571582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW571582 /FEA=EST /DB_XREF=gi:7236313 /DB_XREF=est:xx33d04.x1 /CLONE=IMAGE:2839303 /UG=Hs.26468 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) /FL=gb:AF047348.1 gb:AB014719.1 gb:NM_005503.1 AW571582 amyloid beta (A4) precursor protein-binding, family A, member 2 APBA2 321 NM_001130414 /// NM_005503 /// XM_005254331 /// XM_006720480 /// XM_006720481 /// XM_006725543 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209871_s_at AB014719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014719.1 /DEF=Homo sapiens mRNA for XllL, complete cds. /FEA=mRNA /GEN=hXllL /PROD=XllL /DB_XREF=gi:3953612 /UG=Hs.26468 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) /FL=gb:AF047348.1 gb:AB014719.1 gb:NM_005503.1 AB014719 amyloid beta (A4) precursor protein-binding, family A, member 2 APBA2 321 NM_001130414 /// NM_005503 /// XM_005254331 /// XM_006720480 /// XM_006720481 /// XM_006725543 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209872_s_at BF001503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001503 /FEA=EST /DB_XREF=gi:10701778 /DB_XREF=est:7g89b02.x1 /CLONE=IMAGE:3313611 /UG=Hs.26557 plakophilin 3 /FL=gb:BC000081.1 gb:NM_007183.1 gb:AF053719.1 BF001503 plakophilin 3 PKP3 11187 NM_007183 /// XM_005252760 0002159 // desmosome assembly // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 209873_s_at AF053719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053719.1 /DEF=Homo sapiens plakophilin-3 protein mRNA, complete cds. /FEA=mRNA /PROD=plakophilin-3 protein /DB_XREF=gi:6670884 /UG=Hs.26557 plakophilin 3 /FL=gb:BC000081.1 gb:NM_007183.1 gb:AF053719.1 AF053719 plakophilin 3 PKP3 11187 NM_007183 /// XM_005252760 0002159 // desmosome assembly // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 209874_x_at AF216962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF216962.1 /DEF=Homo sapiens ancient conserved domain protein 2 (ACDP2) mRNA, complete cds. /FEA=mRNA /GEN=ACDP2 /PROD=ancient conserved domain protein 2 /DB_XREF=gi:9280369 /UG=Hs.271221 hypothetical protein FLJ20064 /FL=gb:AF216962.1 AF216962 cyclin M2 CNNM2 54805 NM_017649 /// NM_199076 /// NM_199077 /// XM_005269933 /// XM_006717908 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0016311 // dephosphorylation // /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017144 // drug metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008253 // 5'-nucleotidase activity // /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0008253 // 5'-nucleotidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050146 // nucleoside phosphotransferase activity // traceable author statement 209875_s_at M83248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M83248.1 /DEF=Human nephropontin mRNA, complete cds. /FEA=mRNA /GEN=nephropontin /PROD=nephropontin /DB_XREF=gi:189150 /UG=Hs.313 secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) /FL=gb:M83248.1 M83248 secreted phosphoprotein 1 SPP1 6696 NM_000582 /// NM_001040058 /// NM_001040060 /// NM_001251829 /// NM_001251830 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007566 // embryo implantation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from direct assay /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0046697 // decidualization // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048685 // negative regulation of collateral sprouting of intact axon in response to injury // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 209876_at AF124491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF124491.1 /DEF=Homo sapiens ARF GTPase-activating protein GIT2 (KIAA0148) mRNA, complete cds. /FEA=mRNA /GEN=KIAA0148 /PROD=ARF GTPase-activating protein GIT2 /DB_XREF=gi:4691727 /UG=Hs.57734 G protein-coupled receptor kinase-interactor 2 /FL=gb:AF124491.1 AF124491 G protein-coupled receptor kinase interacting ArfGAP 2 GIT2 9815 NM_001135213 /// NM_001135214 /// NM_014776 /// NM_057169 /// NM_057170 /// NM_139201 /// XM_005253997 /// XM_005254000 /// XM_006719707 /// XM_006719708 /// XM_006719709 /// XM_006719710 /// XM_006719711 /// XM_006719712 /// XM_006719713 /// XM_006719714 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045095 // keratin filament // inferred from direct assay /// 0045179 // apical cortex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209877_at AF010126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010126.1 /DEF=Homo sapiens breast cancer-specific protein 1 (BCSG1) mRNA, complete cds. /FEA=mRNA /GEN=BCSG1 /PROD=BCSG1 protein /DB_XREF=gi:2281473 /UG=Hs.63236 synuclein, gamma (breast cancer-specific protein 1) /FL=gb:AF010126.1 gb:AF017256.1 gb:NM_003087.1 AF010126 synuclein, gamma (breast cancer-specific protein 1) SNCG 6623 NM_003087 /// XM_005270065 /// XM_005270066 /// XM_005270067 0002118 // aggressive behavior // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0071464 // cellular response to hydrostatic pressure // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 209878_s_at M62399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M62399.1 /DEF=Human NF-kappa-B transcription factor p65 DNA binding subunit mRNA, complete cds. /FEA=mRNA /PROD=NF-kappa-B transcription factor /DB_XREF=gi:189503 /UG=Hs.75569 v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) /FL=gb:M62399.1 M62399 v-rel avian reticuloendotheliosis viral oncogene homolog A RELA 5970 NM_001145138 /// NM_001243984 /// NM_001243985 /// NM_021975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006117 // acetaldehyde metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0006968 // cellular defense response // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from direct assay /// 0014040 // positive regulation of Schwann cell differentiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051607 // defense response to virus // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071354 // cellular response to interleukin-6 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from mutant phenotype /// 2000630 // positive regulation of miRNA metabolic process // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0071532 // ankyrin repeat binding // inferred from electronic annotation 209879_at AI741056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741056 /FEA=EST /DB_XREF=gi:5109344 /DB_XREF=est:wg25h08.x1 /CLONE=IMAGE:2366175 /UG=Hs.79283 selectin P ligand /FL=gb:U02297.1 gb:NM_003006.2 AI741056 selectin P ligand SELPLG 6404 NM_001206609 /// NM_003006 /// XM_005269076 /// XM_005269077 /// XM_006719557 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from electronic annotation /// 0050902 // leukocyte adhesive activation // inferred from sequence or structural similarity /// 0071354 // cellular response to interleukin-6 // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209880_s_at U02297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U02297.1 /DEF=Human P-selectin ligand mRNA, complete cds. /FEA=mRNA /PROD=ligand for P-selectin /DB_XREF=gi:435416 /UG=Hs.79283 selectin P ligand /FL=gb:U02297.1 gb:NM_003006.2 U02297 selectin P ligand SELPLG 6404 NM_001206609 /// NM_003006 /// XM_005269076 /// XM_005269077 /// XM_006719557 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from electronic annotation /// 0050902 // leukocyte adhesive activation // inferred from sequence or structural similarity /// 0071354 // cellular response to interleukin-6 // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 209881_s_at AF036905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF036905.1 /DEF=Homo sapiens linker for activation of T cells (LAT) mRNA, complete cds. /FEA=mRNA /GEN=LAT /PROD=LAT /DB_XREF=gi:2828023 /UG=Hs.83496 linker for activation of T cells /FL=gb:AF036905.1 AF036905 linker for activation of T cells LAT 27040 NM_001014987 /// NM_001014988 /// NM_001014989 /// NM_014387 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0010467 // gene expression // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043303 // mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050863 // regulation of T cell activation // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0042629 // mast cell granule // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 209882_at AF084462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF084462.1 /DEF=Homo sapiens GTP-binding protein ROC1 (ROC1) mRNA, complete cds. /FEA=mRNA /GEN=ROC1 /PROD=GTP-binding protein ROC1 /DB_XREF=gi:4234917 /UG=Hs.96038 Ric (Drosophila)-like, expressed in many tissues /FL=gb:U71203.1 gb:U78165.1 gb:AF084462.1 gb:NM_006912.1 AF084462 Ras-like without CAAX 1 RIT1 6016 NM_001256820 /// NM_001256821 /// NM_006912 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 209883_at AF288389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288389.1 /DEF=Homo sapiens C1orf17 mRNA, complete cds. /FEA=mRNA /PROD=C1orf17 /DB_XREF=gi:12620187 /UG=Hs.106794 KIAA0584 protein /FL=gb:AF288389.1 AF288389 collagen beta(1-O)galactosyltransferase 2 COLGALT2 23127 NM_015101 /// XM_005245008 /// XM_005245009 /// XR_241075 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0050211 // procollagen galactosyltransferase activity // inferred from electronic annotation 209884_s_at AF047033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047033.1 /DEF=Homo sapiens sodium bicarbonate cotransporter 3 (SLC4A7) mRNA, complete cds. /FEA=mRNA /GEN=SLC4A7 /PROD=sodium bicarbonate cotransporter 3 /DB_XREF=gi:5051627 /UG=Hs.132904 solute carrier family 4, sodium bicarbonate cotransporter, member 7 /FL=gb:AF047033.1 AF047033 solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 9497 NM_001258379 /// NM_001258380 /// NM_003615 /// XM_005265598 /// XM_005265599 /// XM_005265600 /// XM_005265601 /// XM_006713421 /// XR_245166 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 209885_at BC001338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001338.1 /DEF=Homo sapiens, ras homolog gene family, member, clone MGC:5612, mRNA, complete cds. /FEA=mRNA /PROD=ras homolog gene family, member /DB_XREF=gi:12654980 /UG=Hs.15114 ras homolog gene family, member /FL=gb:BC001338.1 gb:NM_014578.1 BC001338 ras homolog family member D RHOD 29984 NM_014578 /// XM_005273963 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 209886_s_at AI628464 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI628464 /FEA=EST /DB_XREF=gi:4665264 /DB_XREF=est:ty74c10.x1 /CLONE=IMAGE:2284818 /UG=Hs.153863 MAD (mothers against decapentaplegic, Drosophila) homolog 6 /FL=gb:AF035528.1 gb:AF043640.1 gb:AF037469.1 AI628464 SMAD family member 6 SMAD6 4091 NM_001142861 /// NM_005585 /// NR_027654 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from direct assay /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070698 // type I activin receptor binding // inferred from direct assay 209887_at AF035528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035528.1 /DEF=Homo sapiens Smad6 mRNA, complete cds. /FEA=mRNA /PROD=Smad6 /DB_XREF=gi:2736315 /UG=Hs.153863 MAD (mothers against decapentaplegic, Drosophila) homolog 6 /FL=gb:AF035528.1 gb:AF043640.1 gb:AF037469.1 AF035528 SMAD family member 6 SMAD6 4091 NM_001142861 /// NM_005585 /// NR_027654 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from direct assay /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070698 // type I activin receptor binding // inferred from direct assay 209888_s_at M20643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M20643.1 /DEF=Human alkali myosin light chain 3 mRNA, complete cds. /FEA=mRNA /GEN=MYL1 /PROD=myosin light chain /DB_XREF=gi:188593 /UG=Hs.158295 Homo sapiens, clone MGC:12401, mRNA, complete cds /FL=gb:BC005318.1 gb:M20643.1 M20643 myosin, light chain 1, alkali; skeletal, fast MYL1 4632 NM_079420 /// NM_079422 0006936 // muscle contraction // inferred from direct assay /// 0007517 // muscle organ development // non-traceable author statement /// 0030049 // muscle filament sliding // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from direct assay /// 0030017 // sarcomere // non-traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement 209889_at AF274863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274863.1 /DEF=Homo sapiens secretory pathway component Sec31B-1 mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=secretory pathway component Sec31B-1 /DB_XREF=gi:8650513 /UG=Hs.18889 DKFZP434M183 protein /FL=gb:AF274863.1 AF274863 SEC31 homolog B (S. cerevisiae) SEC31B 25956 NM_015490 /// NM_198138 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030120 // vesicle coat // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 209890_at AF065389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF065389.1 /DEF=Homo sapiens tetraspan NET-4 mRNA, complete cds. /FEA=mRNA /PROD=tetraspan NET-4 /DB_XREF=gi:3152702 /UG=Hs.20709 tetraspan 5 /FL=gb:AF065389.1 gb:NM_005723.1 AF065389 tetraspanin 5 TSPAN5 10098 NM_005723 /// XM_005262680 /// XR_244617 0045747 // positive regulation of Notch signaling pathway // inferred from mutant phenotype /// 0051604 // protein maturation // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction 209891_at AF225416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225416.1 /DEF=Homo sapiens AD024 mRNA, complete cds. /FEA=mRNA /PROD=AD024 /DB_XREF=gi:9963834 /UG=Hs.21137 AD024 protein /FL=gb:NM_020675.1 gb:AF225416.1 AF225416 SPC25, NDC80 kinetochore complex component SPC25 57405 NM_020675 /// XM_005246702 /// XM_005276750 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031262 // Ndc80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209892_at AF305083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF305083.1 /DEF=Homo sapiens alpha(1,3)-fucosyltransferase IV (FUTIV) gene, 3 UTR. /FEA=mRNA /DB_XREF=gi:11096240 /UG=Hs.2173 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) /FL=gb:M58596.1 gb:M58597.1 gb:NM_002033.1 AF305083 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) FUT4 2526 NM_002033 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 209893_s_at M58596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M58596.1 /DEF=Human ELAM-1 ligand fucosyltransferase (ELFT) mRNA, complete cds. /FEA=mRNA /PROD=ELAM-1 ligand fucosyltransferase /DB_XREF=gi:182068 /UG=Hs.2173 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) /FL=gb:M58596.1 gb:M58597.1 gb:NM_002033.1 M58596 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) FUT4 2526 NM_002033 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 209894_at U50748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U50748.1 /DEF=Homo sapiens leptin receptor short form (db) mRNA, complete cds. /FEA=mRNA /GEN=db /PROD=leptin receptor /DB_XREF=gi:3236285 /UG=Hs.226627 leptin receptor /FL=gb:U50748.1 U50748 leptin receptor /// leptin receptor overlapping transcript LEPR /// LEPROT 3953 /// 54741 NM_001003679 /// NM_001003680 /// NM_001198681 /// NM_001198683 /// NM_001198687 /// NM_001198688 /// NM_001198689 /// NM_002303 /// NM_017526 0006112 // energy reserve metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 209895_at AF119855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119855.1 /DEF=Homo sapiens PRO1847 mRNA, complete cds. /FEA=mRNA /PROD=PRO1847 /DB_XREF=gi:7770146 /UG=Hs.285196 hypothetical protein PRO1847 /FL=gb:AF119855.1 AF119855 protein tyrosine phosphatase, non-receptor type 11 PTPN11 5781 NM_002834 /// NM_080601 /// XM_006719526 /// XM_006719527 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036302 // atrioventricular canal development // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051463 // negative regulation of cortisol secretion // inferred from electronic annotation /// 0060125 // negative regulation of growth hormone secretion // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 209896_s_at AF119855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119855.1 /DEF=Homo sapiens PRO1847 mRNA, complete cds. /FEA=mRNA /PROD=PRO1847 /DB_XREF=gi:7770146 /UG=Hs.285196 hypothetical protein PRO1847 /FL=gb:AF119855.1 AF119855 protein tyrosine phosphatase, non-receptor type 11 PTPN11 5781 NM_002834 /// NM_080601 /// XM_006719526 /// XM_006719527 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036302 // atrioventricular canal development // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051463 // negative regulation of cortisol secretion // inferred from electronic annotation /// 0060125 // negative regulation of growth hormone secretion // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 209897_s_at AF055585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF055585.1 /DEF=Homo sapiens neurogenic extracellular slit protein Slit2 mRNA, complete cds. /FEA=mRNA /PROD=neurogenic extracellular slit protein Slit2 /DB_XREF=gi:4151204 /UG=Hs.29802 slit (Drosophila) homolog 2 /FL=gb:AF055585.1 gb:AF133270.1 AF055585 slit homolog 2 (Drosophila) SLIT2 9353 NM_001289135 /// NM_001289136 /// NM_004787 /// XM_005248211 /// XM_005248214 /// XM_006713986 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002689 // negative regulation of leukocyte chemotaxis // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010593 // negative regulation of lamellipodium assembly // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0021836 // chemorepulsion involved in postnatal olfactory bulb interneuron migration // inferred from direct assay /// 0021972 // corticospinal neuron axon guidance through spinal cord // inferred from mutant phenotype /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030837 // negative regulation of actin filament polymerization // inferred from direct assay /// 0031290 // retinal ganglion cell axon guidance // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0035385 // Roundabout signaling pathway // inferred by curator /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050919 // negative chemotaxis // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from mutant phenotype /// 0050929 // induction of negative chemotaxis // inferred from direct assay /// 0051058 // negative regulation of small GTPase mediated signal transduction // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071672 // negative regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0071676 // negative regulation of mononuclear cell migration // inferred from direct assay /// 0090024 // negative regulation of neutrophil chemotaxis // inferred from direct assay /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity /// 0090260 // negative regulation of retinal ganglion cell axon guidance // inferred from direct assay /// 0090288 // negative regulation of cellular response to growth factor stimulus // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005095 // GTPase inhibitor activity // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0045499 // chemorepellent activity // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 209898_x_at U61167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U61167.1 /DEF=Human SH3 domain-containing protein SH3P18 mRNA, complete cds. /FEA=mRNA /PROD=SH3 domain-containing protein SH3P18 /DB_XREF=gi:1438934 /UG=Hs.330549 Human SH3 domain-containing protein SH3P18 mRNA, complete cds /FL=gb:U61167.1 U61167 intersectin 2 ITSN2 50618 NM_006277 /// NM_019595 /// NM_147152 0006897 // endocytosis // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209899_s_at AF217197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF217197.1 /DEF=Homo sapiens FBP interacting repressor (FIR) mRNA, complete cds. /FEA=mRNA /GEN=FIR /PROD=FBP interacting repressor /DB_XREF=gi:6740005 /UG=Hs.74562 siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1 /FL=gb:AF217197.1 AF217197 poly-U binding splicing factor 60KDa PUF60 22827 NM_001136033 /// NM_001271096 /// NM_001271097 /// NM_001271098 /// NM_001271099 /// NM_001271100 /// NM_014281 /// NM_078480 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209900_s_at AL162079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL162079.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762B2310 (from clone DKFZp762B2310); complete cds. /FEA=mRNA /GEN=DKFZp762B2310 /PROD=hypothetical protein /DB_XREF=gi:7328161 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:AL162079.1 AL162079 solute carrier family 16 (monocarboxylate transporter), member 1 SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 209901_x_at U19713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19713.1 /DEF=Human allograft-inflammatory factor-1 mRNA, complete cds. /FEA=mRNA /PROD=allograft-inflammatory factor-1 /DB_XREF=gi:1122908 /UG=Hs.76364 allograft inflammatory factor 1 /FL=gb:U19713.1 gb:U49392.1 gb:D86438.1 gb:NM_001623.2 U19713 allograft inflammatory factor 1 AIF1 199 NM_001623 /// NM_004847 /// NM_032955 /// XM_005248869 /// XM_005248870 /// XM_005248871 /// XM_005272777 /// XM_005272778 /// XM_005272779 /// XM_005274923 /// XM_005274924 /// XM_005274925 /// XM_005275219 /// XM_005275220 /// XM_005275221 /// XM_005275355 /// XM_005275356 /// XM_005275357 /// XM_005275514 /// XM_005275515 /// XM_005275516 0001774 // microglial cell activation // non-traceable author statement /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006954 // inflammatory response // non-traceable author statement /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030041 // actin filament polymerization // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from sequence or structural similarity /// 0071672 // negative regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0097178 // ruffle assembly // inferred from sequence or structural similarity /// 0097178 // ruffle assembly // non-traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 209902_at U49844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49844.1 /DEF=Human FRAP-related protein (FRP1) mRNA, complete cds. /FEA=mRNA /GEN=FRP1 /PROD=FRAP-related protein /DB_XREF=gi:1235901 /UG=Hs.77613 ataxia telangiectasia and Rad3 related /FL=gb:U49844.1 gb:U76308.1 gb:NM_001184.1 U49844 ATR serine/threonine kinase ATR 545 NM_001184 /// XR_241498 0000077 // DNA damage checkpoint // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0090399 // replicative senescence // inferred from mutant phenotype 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay 209903_s_at U49844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49844.1 /DEF=Human FRAP-related protein (FRP1) mRNA, complete cds. /FEA=mRNA /GEN=FRP1 /PROD=FRAP-related protein /DB_XREF=gi:1235901 /UG=Hs.77613 ataxia telangiectasia and Rad3 related /FL=gb:U49844.1 gb:U76308.1 gb:NM_001184.1 U49844 ATR serine/threonine kinase ATR 545 NM_001184 /// XR_241498 0000077 // DNA damage checkpoint // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0090399 // replicative senescence // inferred from mutant phenotype 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay 209904_at AF020769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020769.1 /DEF=Homo sapiens cardiac ventricular troponin C mRNA, complete cds. /FEA=mRNA /PROD=cardiac ventricular troponin C /DB_XREF=gi:2460248 /UG=Hs.118845 troponin C, slow /FL=gb:AF020769.1 gb:NM_003280.1 AF020769 troponin C type 1 (slow) TNNC1 7134 NM_003280 0002086 // diaphragm contraction // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from direct assay /// 0006937 // regulation of muscle contraction // traceable author statement /// 0010038 // response to metal ion // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0032972 // regulation of muscle filament sliding speed // inferred from sequence or structural similarity /// 0043462 // regulation of ATPase activity // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031013 // troponin I binding // inferred from direct assay /// 0031013 // troponin I binding // inferred from physical interaction /// 0031014 // troponin T binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from sequence or structural similarity 209905_at AI246769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI246769 /FEA=EST /DB_XREF=gi:3842166 /DB_XREF=est:qk40f08.x1 /CLONE=IMAGE:1871463 /UG=Hs.127428 homeo box A9 /FL=gb:U82759.1 AI246769 HOXA10-HOXA9 readthrough /// homeobox A9 /// microRNA 196b HOXA10-HOXA9 /// HOXA9 /// MIR196B 3205 /// 442920 /// 100534589 NM_152739 /// NR_029911 /// NR_037940 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209906_at U62027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62027.1 /DEF=Human anaphylatoxin C3a receptor (HNFAG09) mRNA, complete cds. /FEA=mRNA /GEN=HNFAG09 /PROD=anaphylatoxin C3a receptor /DB_XREF=gi:1511643 /UG=Hs.155935 complement component 3a receptor 1 /FL=gb:U28488.1 gb:U62027.1 gb:NM_004054.1 U62027 complement component 3a receptor 1 C3AR1 719 NM_004054 0002430 // complement receptor mediated signaling pathway // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0008015 // blood circulation // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from electronic annotation /// 0010759 // positive regulation of macrophage chemotaxis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004876 // complement component C3a receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from genetic interaction /// 0004942 // anaphylatoxin receptor activity // inferred from electronic annotation /// 0004943 // C3a anaphylatoxin receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 209907_s_at AF182198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182198.1 /DEF=Homo sapiens intersectin 2 long isoform (ITSN2) mRNA, complete cds. /FEA=mRNA /GEN=ITSN2 /PROD=intersectin 2 long isoform /DB_XREF=gi:7329075 /UG=Hs.166184 intersectin 2 /FL=gb:AF182198.1 AF182198 intersectin 2 ITSN2 50618 NM_006277 /// NM_019595 /// NM_147152 0006897 // endocytosis // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209908_s_at BF061658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF061658 /FEA=EST /DB_XREF=gi:10820568 /DB_XREF=est:7i82e10.x1 /CLONE=IMAGE:3341226 /UG=Hs.169300 transforming growth factor, beta 2 /FL=gb:M19154.1 BF061658 transforming growth factor, beta 2 TGFB2 7042 NM_001135599 /// NM_003238 /// XR_247036 /// XR_247037 0000902 // cell morphogenesis // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001654 // eye development // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001942 // hair follicle development // inferred from direct assay /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007507 // heart development // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008347 // glial cell migration // inferred from direct assay /// 0009611 // response to wounding // inferred from expression pattern /// 0009790 // embryo development // traceable author statement /// 0010002 // cardioblast differentiation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042416 // dopamine biosynthetic process // inferred from sequence or structural similarity /// 0042476 // odontogenesis // non-traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042637 // catagen // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045823 // positive regulation of heart contraction // inferred from direct assay /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048699 // generation of neurons // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050777 // negative regulation of immune response // traceable author statement /// 0050778 // positive regulation of immune response // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from direct assay /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0060038 // cardiac muscle cell proliferation // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070237 // positive regulation of activation-induced cell death of T cells // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement 209909_s_at M19154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M19154.1 /DEF=Human transforming growth factor-beta-2 mRNA, complete cds. /FEA=mRNA /PROD=transforming growth factor beta 2 /DB_XREF=gi:339549 /UG=Hs.169300 transforming growth factor, beta 2 /FL=gb:M19154.1 M19154 transforming growth factor, beta 2 TGFB2 7042 NM_001135599 /// NM_003238 /// XR_247036 /// XR_247037 0000902 // cell morphogenesis // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001654 // eye development // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001942 // hair follicle development // inferred from direct assay /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007507 // heart development // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008347 // glial cell migration // inferred from direct assay /// 0009611 // response to wounding // inferred from expression pattern /// 0009790 // embryo development // traceable author statement /// 0010002 // cardioblast differentiation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042416 // dopamine biosynthetic process // inferred from sequence or structural similarity /// 0042476 // odontogenesis // non-traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042637 // catagen // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045823 // positive regulation of heart contraction // inferred from direct assay /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048699 // generation of neurons // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050777 // negative regulation of immune response // traceable author statement /// 0050778 // positive regulation of immune response // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from direct assay /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0060038 // cardiac muscle cell proliferation // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070237 // positive regulation of activation-induced cell death of T cells // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement 209910_at M31659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31659.1 /DEF=Human GT mitochondrial solute carrier protein homologue mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:188697 /UG=Hs.180408 solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 /FL=gb:M31659.1 M31659 solute carrier family 25 (mitochondrial carrier), member 16 SLC25A16 8034 NM_152707 /// XM_005270183 /// XM_006717987 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // non-traceable author statement /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // non-traceable author statement 209911_x_at BC002842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002842.1 /DEF=Homo sapiens, H2B histone family, member B, clone MGC:3802, mRNA, complete cds. /FEA=mRNA /PROD=H2B histone family, member B /DB_XREF=gi:12803984 /UG=Hs.180779 H2B histone family, member B /FL=gb:NM_021063.1 gb:BC002842.1 BC002842 histone cluster 1, H2bd HIST1H2BD 3017 NM_021063 /// NM_138720 /// XM_005249039 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209912_s_at AI373854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI373854 /FEA=EST /DB_XREF=gi:4153720 /DB_XREF=est:qz96b07.x1 /CLONE=IMAGE:2042389 /UG=Hs.229950 KIAA0415 gene product /FL=gb:AB007875.1 AI373854 adaptor-related protein complex 5, zeta 1 subunit /// microRNA 4656 AP5Z1 /// MIR4656 9907 /// 100616465 NM_014855 /// NR_039800 /// XR_242109 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030119 // AP-type membrane coat adaptor complex // non-traceable author statement /// 0044599 // AP-5 adaptor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209913_x_at AB007875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007875.1 /DEF=Homo sapiens KIAA0415 mRNA, complete cds. /FEA=mRNA /GEN=KIAA0415 /DB_XREF=gi:2887450 /UG=Hs.229950 KIAA0415 gene product /FL=gb:AB007875.1 AB007875 adaptor-related protein complex 5, zeta 1 subunit /// microRNA 4656 AP5Z1 /// MIR4656 9907 /// 100616465 NM_014855 /// NR_039800 /// XR_242109 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030119 // AP-type membrane coat adaptor complex // non-traceable author statement /// 0044599 // AP-5 adaptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209914_s_at AW149405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149405 /FEA=EST /DB_XREF=gi:6197301 /DB_XREF=est:xf36g04.x1 /CLONE=IMAGE:2620182 /UG=Hs.22998 neurexin 1 /FL=gb:AB035356.1 AW149405 neurexin 1 NRXN1 9378 NM_001135659 /// NM_004801 /// NM_138735 /// XM_005264642 /// XM_005264643 /// XM_006712133 /// XM_006712134 /// XM_006712135 /// XM_006712136 /// XM_006712137 /// XM_006712138 /// XM_006712139 /// XM_006712140 /// XM_006712141 /// XM_006712142 /// XM_006712143 /// XM_006712144 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from sequence or structural similarity /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0023041 // neuronal signal transduction // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035418 // protein localization to synapse // inferred from sequence or structural similarity /// 0042297 // vocal learning // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0051490 // negative regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 0097091 // synaptic vesicle clustering // inferred from sequence or structural similarity /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097112 // gamma-aminobutyric acid receptor clustering // inferred from sequence or structural similarity /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from sequence or structural similarity /// 0097116 // gephyrin clustering // inferred from sequence or structural similarity /// 0097117 // guanylate kinase-associated protein clustering // inferred from sequence or structural similarity /// 0097118 // neuroligin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // traceable author statement /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0033130 // acetylcholine receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity /// 0097109 // neuroligin family protein binding // inferred from sequence or structural similarity 209915_s_at AB035356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035356.1 /DEF=Homo sapiens mRNA for neurexin I-alpha protein, complete cds. /FEA=mRNA /PROD=neurexin I-alpha protein /DB_XREF=gi:6498406 /UG=Hs.22998 neurexin 1 /FL=gb:AB035356.1 AB035356 neurexin 1 NRXN1 9378 NM_001135659 /// NM_004801 /// NM_138735 /// XM_005264642 /// XM_005264643 /// XM_006712133 /// XM_006712134 /// XM_006712135 /// XM_006712136 /// XM_006712137 /// XM_006712138 /// XM_006712139 /// XM_006712140 /// XM_006712141 /// XM_006712142 /// XM_006712143 /// XM_006712144 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from sequence or structural similarity /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0023041 // neuronal signal transduction // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035418 // protein localization to synapse // inferred from sequence or structural similarity /// 0042297 // vocal learning // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0051490 // negative regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 0097091 // synaptic vesicle clustering // inferred from sequence or structural similarity /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097112 // gamma-aminobutyric acid receptor clustering // inferred from sequence or structural similarity /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from sequence or structural similarity /// 0097116 // gephyrin clustering // inferred from sequence or structural similarity /// 0097117 // guanylate kinase-associated protein clustering // inferred from sequence or structural similarity /// 0097118 // neuroligin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // traceable author statement /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0033130 // acetylcholine receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity /// 0097109 // neuroligin family protein binding // inferred from sequence or structural similarity 209916_at BC002477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002477.1 /DEF=Homo sapiens, clone MGC:3090, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3090) /DB_XREF=gi:12803318 /UG=Hs.271586 hypothetical protein DKFZp762M115 /FL=gb:BC002477.1 BC002477 dehydrogenase E1 and transketolase domain containing 1 DHTKD1 55526 NM_018706 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation 209917_s_at BC002709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002709.1 /DEF=Homo sapiens, TP53 target gene 1, clone MGC:3578, mRNA, complete cds. /FEA=mRNA /PROD=TP53 target gene 1 /DB_XREF=gi:12803742 /UG=Hs.274329 TP53 target gene 1 /FL=gb:BC002709.1 gb:AB007455.1 gb:NM_007233.1 BC002709 TP53 target 1 (non-protein coding) TP53TG1 11257 NM_007233 /// NR_015381 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement 209918_at J05235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J05235.1 /DEF=Human gamma-glutamyl transpeptidase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183143 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:J05235.1 gb:L20490.1 J05235 gamma-glutamyltransferase light chain 2 GGTLC2 91227 NM_001282879 /// NM_080839 /// NM_199127 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay /// 0036374 // glutathione hydrolase activity // inferred from electronic annotation 209919_x_at L20490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20490.1 /DEF=Human gamma-glutamyl transpeptidase mRNA, complete cds. /FEA=mRNA /PROD=gamma-glutamyl transpeptidase /DB_XREF=gi:306748 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:J05235.1 gb:L20490.1 L20490 gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 2 /// gamma-glutamyltransferase light chain 1 /// gamma-glutamyltransferase light chain 2 GGT1 /// GGT2 /// GGTLC1 /// GGTLC2 2678 /// 91227 /// 92086 /// 728441 NM_001032364 /// NM_001032365 /// NM_001282879 /// NM_001288833 /// NM_005265 /// NM_013421 /// NM_013430 /// NM_080839 /// NM_080920 /// NM_178311 /// NM_178312 /// NM_199127 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_005261888 /// XM_005261890 /// XM_006723661 /// XM_006723662 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 /// XM_006724392 /// XM_006724393 /// XM_006724394 /// XM_006724395 /// XM_006724396 /// XM_006724397 /// XM_006726820 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from mutant phenotype /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // inferred from direct assay /// 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay 209920_at U20165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20165.1 /DEF=Human type II serinethreonine kinase receptor mRNA, complete cds. /FEA=mRNA /PROD=type II serinethreonine kinase receptor /DB_XREF=gi:704361 /UG=Hs.53250 bone morphogenetic protein receptor, type II (serinethreonine kinase) /FL=gb:NM_001204.2 gb:U20165.1 gb:D50516.1 U20165 bone morphogenetic protein receptor, type II (serine/threonine kinase) BMPR2 659 NM_001204 /// NM_033346 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from mutant phenotype /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032924 // activin receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045906 // negative regulation of vasoconstriction // inferred from sequence or structural similarity /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060836 // lymphatic endothelial cell differentiation // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from sequence or structural similarity /// 0060841 // venous blood vessel development // inferred from sequence or structural similarity /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 1902731 // negative regulation of chondrocyte proliferation // inferred from mutant phenotype /// 2000279 // negative regulation of DNA biosynthetic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from mutant phenotype /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044214 // fully spanning plasma membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016362 // activin receptor activity, type II // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209921_at AB040875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB040875.1 /DEF=Homo sapiens hxCT mRNA for cystineglutamate exchanger, complete cds. /FEA=mRNA /GEN=hxCT /PROD=cystineglutamate exchanger /DB_XREF=gi:13516845 /UG=Hs.6682 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 /FL=gb:AB040875.1 AB040875 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 SLC7A11 23657 NM_014331 /// XM_005262875 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0015813 // L-glutamate transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015327 // cystine:glutamate antiporter activity // traceable author statement 209922_at AF035620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035620.1 /DEF=Homo sapiens BRCA1-associated protein 2 (BRAP2) mRNA, complete cds. /FEA=mRNA /GEN=BRAP2 /PROD=BRCA1-associated protein 2 /DB_XREF=gi:3252871 /UG=Hs.122764 BRCA1 associated protein /FL=gb:NM_006768.2 gb:AF035620.1 AF035620 BRCA1 associated protein BRAP 8315 NM_006768 /// XM_005253944 0000165 // MAPK cascade // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209923_s_at AF035620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035620.1 /DEF=Homo sapiens BRCA1-associated protein 2 (BRAP2) mRNA, complete cds. /FEA=mRNA /GEN=BRAP2 /PROD=BRCA1-associated protein 2 /DB_XREF=gi:3252871 /UG=Hs.122764 BRCA1 associated protein /FL=gb:NM_006768.2 gb:AF035620.1 AF035620 BRCA1 associated protein BRAP 8315 NM_006768 /// XM_005253944 0000165 // MAPK cascade // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209924_at AB000221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000221.1 /DEF=Homo sapiens mRNA for CC chemokine, complete cds. /FEA=mRNA /GEN=PARC /PROD=CC chemokine /DB_XREF=gi:2289718 /UG=Hs.16530 small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated /FL=gb:AB000221.1 gb:NM_002988.1 AB000221 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) CCL18 6362 NM_002988 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009607 // response to biotic stimulus // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation 209925_at U53823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U53823.1 /DEF=Human tight junction protein occludin mRNA, complete cds. /FEA=mRNA /PROD=occludin /DB_XREF=gi:1322281 /UG=Hs.171952 occludin /FL=gb:U49184.1 gb:U53823.1 gb:NM_002538.2 U53823 occludin OCLN 100506658 NM_001205254 /// NM_001205255 /// NM_002538 /// XM_006714512 /// XM_006726213 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from mutant phenotype 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008119 // thiopurine S-methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 209926_at BC004449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004449.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 2310045N01 gene, clone MGC:4187, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 2310045N01 gene /DB_XREF=gi:13325262 /UG=Hs.307040 Homo sapiens, Similar to RIKEN cDNA 2310045N01 gene, clone MGC:4187, mRNA, complete cds /FL=gb:BC004449.1 BC004449 MEF2B neighbor MEF2BNB 729991 NM_001145783 /// NM_001145784 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 209927_s_at AF261137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF261137.1 /DEF=Homo sapiens HT031 mRNA, complete cds. /FEA=mRNA /PROD=HT031 /DB_XREF=gi:12005923 /UG=Hs.323817 DKFZP547E1010 protein /FL=gb:AF261137.1 gb:BC002733.1 AF261137 chromatin target of PRMT1 CHTOP 26097 NM_001206612 /// NM_001244664 /// NM_015607 /// XM_005245085 /// XM_005245086 /// XM_006711269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209928_s_at AF060154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF060154.1 /DEF=Homo sapiens activated B-cell factor-1 (ABF-1) mRNA, complete cds. /FEA=mRNA /GEN=ABF-1 /PROD=activated B-cell factor-1 /DB_XREF=gi:3089604 /UG=Hs.42474 musculin (activated B-cell factor-1) /FL=gb:AF060154.1 gb:NM_005098.2 AF060154 musculin MSC 9242 NM_005098 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0014707 // branchiomeric skeletal muscle development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060539 // diaphragm development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 209929_s_at AF091453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF091453.1 /DEF=Homo sapiens NEMO protein (NEMO) mRNA, complete cds. /FEA=mRNA /GEN=NEMO /PROD=NEMO protein /DB_XREF=gi:5031140 /UG=Hs.43505 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma /FL=gb:AF091453.1 AF091453 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma IKBKG 8517 NM_001099856 /// NM_001099857 /// NM_001145255 /// NM_003639 /// XM_005274760 /// XM_005274761 /// XM_005274763 /// XM_005274764 /// XM_006724853 0000187 // activation of MAPK activity // traceable author statement /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007254 // JNK cascade // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0008385 // IkappaB kinase complex // traceable author statement 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 209930_s_at L13974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L13974.1 /DEF=Human leucine zipper mRNA, complete cds. /FEA=mRNA /PROD=leucine zipper protein /DB_XREF=gi:506817 /UG=Hs.75643 nuclear factor (erythroid-derived 2), 45kD /FL=gb:BC005044.1 gb:L24122.1 gb:L13974.1 L13974 nuclear factor, erythroid 2 NFE2 4778 NM_001136023 /// NM_001261461 /// NM_006163 /// XM_005268906 /// XM_005268907 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0034242 // negative regulation of syncytium formation by plasma membrane fusion // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 2000758 // positive regulation of peptidyl-lysine acetylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // traceable author statement /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 209931_s_at AF322070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF322070.1 /DEF=Homo sapiens FK506-binding protein FKBP9 mRNA, complete cds. /FEA=mRNA /PROD=FK506-binding protein FKBP9 /DB_XREF=gi:12963276 /UG=Hs.77643 FK506-binding protein 1B (12.6 kD) /FL=gb:BC002614.1 gb:AF322070.1 AF322070 FK506 binding protein 1B, 12.6 kDa /// major facilitator superfamily domain containing 2B FKBP1B /// MFSD2B 2281 /// 388931 NM_001080473 /// NM_004116 /// NM_054033 /// XM_005264301 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006936 // muscle contraction // non-traceable author statement /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // not recorded /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030073 // insulin secretion // inferred from electronic annotation /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0048680 // positive regulation of axon regeneration // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051284 // positive regulation of sequestering of calcium ion // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from genetic interaction /// 0051775 // response to redox state // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from mutant phenotype /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // not recorded /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // not recorded /// 0034704 // calcium channel complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0030551 // cyclic nucleotide binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from sequence or structural similarity 209932_s_at U90223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90223.1 /DEF=Human deoxyuridine triphosphate nucleotidohydrolase precursor mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=deoxyuridine triphosphate nucleotidohydrolaseprecursor /DB_XREF=gi:2735291 /UG=Hs.82113 dUTP pyrophosphatase /FL=gb:U90223.1 U90223 deoxyuridine triphosphatase DUT 1854 NM_001025248 /// NM_001025249 /// NM_001948 /// XM_005254211 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006226 // dUMP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046080 // dUTP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004170 // dUTP diphosphatase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 209933_s_at AF020314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020314.1 /DEF=Homo sapiens CMRF-35-H9 mRNA, complete cds. /FEA=mRNA /PROD=CMRF-35-H9 /DB_XREF=gi:4103065 /UG=Hs.9688 leukocyte membrane antigen /FL=gb:AF020314.1 AF020314 CD300a molecule CD300A 11314 NM_001256841 /// NM_007261 /// XM_005256990 /// XM_005256991 /// XM_005256992 /// XM_006721656 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0033007 // negative regulation of mast cell activation involved in immune response // inferred from direct assay /// 0043305 // negative regulation of mast cell degranulation // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050856 // regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050859 // negative regulation of B cell receptor signaling pathway // inferred from direct assay /// 0051134 // negative regulation of NK T cell activation // inferred from direct assay /// 0060101 // negative regulation of phagocytosis, engulfment // inferred from mutant phenotype /// 1902564 // negative regulation of neutrophil activation // inferred from direct assay /// 1902567 // negative regulation of eosinophil activation // inferred from direct assay /// 1902569 // negative regulation of activation of JAK2 kinase activity // inferred from direct assay /// 2000417 // negative regulation of eosinophil migration // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0038023 // signaling receptor activity // inferred from direct assay 209934_s_at AF225981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225981.1 /DEF=Homo sapiens calcium transport ATPase ATP2C1 (ATP2C1) mRNA, complete cds. /FEA=mRNA /GEN=ATP2C1 /PROD=calcium transport ATPase ATP2C1 /DB_XREF=gi:7021496 /UG=Hs.106778 ATPase, Ca++ transporting, type 2C, member 1 /FL=gb:AF225981.1 AF225981 ATPase, Ca++ transporting, type 2C, member 1 ATP2C1 27032 NM_001001485 /// NM_001001486 /// NM_001001487 /// NM_001199179 /// NM_001199180 /// NM_001199181 /// NM_001199182 /// NM_001199183 /// NM_001199184 /// NM_001199185 /// NM_014382 /// XM_005247354 /// XM_005247355 /// XM_005247356 /// XM_005247357 /// XM_005247358 /// XM_005247359 /// XM_006713585 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from mutant phenotype /// 0030026 // cellular manganese ion homeostasis // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032468 // Golgi calcium ion homeostasis // inferred from mutant phenotype /// 0032472 // Golgi calcium ion transport // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 0071421 // manganese ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015410 // manganese-transporting ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209935_at AF225981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225981.1 /DEF=Homo sapiens calcium transport ATPase ATP2C1 (ATP2C1) mRNA, complete cds. /FEA=mRNA /GEN=ATP2C1 /PROD=calcium transport ATPase ATP2C1 /DB_XREF=gi:7021496 /UG=Hs.106778 ATPase, Ca++ transporting, type 2C, member 1 /FL=gb:AF225981.1 AF225981 ATPase, Ca++ transporting, type 2C, member 1 ATP2C1 27032 NM_001001485 /// NM_001001486 /// NM_001001487 /// NM_001199179 /// NM_001199180 /// NM_001199181 /// NM_001199182 /// NM_001199183 /// NM_001199184 /// NM_001199185 /// NM_014382 /// XM_005247354 /// XM_005247355 /// XM_005247356 /// XM_005247357 /// XM_005247358 /// XM_005247359 /// XM_006713585 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from mutant phenotype /// 0030026 // cellular manganese ion homeostasis // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032468 // Golgi calcium ion homeostasis // inferred from mutant phenotype /// 0032472 // Golgi calcium ion transport // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 0071421 // manganese ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015410 // manganese-transporting ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209936_at AF107493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF107493.1 /DEF=Homo sapiens LUCA-15 protein mRNA, splice variant, complete cds. /FEA=mRNA /PROD=LUCA-15 protein /DB_XREF=gi:9801844 /UG=Hs.118498 Homo sapiens LUCA-15 protein mRNA, splice variant, complete cds /FL=gb:AF107493.1 AF107493 RNA binding motif protein 5 RBM5 10181 NM_005778 /// NR_036627 /// XM_006712917 /// XM_006712918 /// XM_006712919 /// XM_006712920 /// XR_427245 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209937_at BC001386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001386.1 /DEF=Homo sapiens, transmembrane 4 superfamily member 4, clone MGC:1477, mRNA, complete cds. /FEA=mRNA /PROD=transmembrane 4 superfamily member 4 /DB_XREF=gi:12655070 /UG=Hs.11881 transmembrane 4 superfamily member 4 /FL=gb:BC001386.1 gb:NM_004617.1 gb:U31449.1 BC001386 transmembrane 4 L six family member 4 TM4SF4 7104 NM_004617 0042246 // tissue regeneration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 209938_at AF064094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064094.1 /DEF=Homo sapiens KL04P mRNA, complete cds. /FEA=mRNA /PROD=KL04P /DB_XREF=gi:3258662 /UG=Hs.125156 transcriptional adaptor 2 (ADA2, yeast, homolog)-like /FL=gb:AF064094.1 gb:AF069732.1 gb:NM_001488.1 AF064094 transcriptional adaptor 2A TADA2A 6871 NM_001166105 /// NM_001291918 /// NM_001488 /// NM_133439 /// XM_005257628 /// XM_006722043 /// XM_006722044 /// XM_006722045 /// XM_006722046 /// XM_006722047 /// XM_006725335 /// XM_006725336 /// XM_006725337 /// XM_006725338 /// XM_006725339 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0090043 // regulation of tubulin deacetylation // inferred from electronic annotation 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation 209939_x_at AF005775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005775.1 /DEF=Homo sapiens caspase-like apoptosis regulatory protein 2 (clarp) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=clarp /PROD=caspase-like apoptosis regulatory protein 2 /DB_XREF=gi:2286146 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF005775.1 AF005775 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 209940_at AF083068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083068.1 /DEF=Homo sapiens NAD+ ADP-ribosyltransferase 3 (ADPRT3) mRNA, complete cds. /FEA=mRNA /GEN=ADPRT3 /PROD=NAD+ ADP-ribosyltransferase 3 /DB_XREF=gi:4808551 /UG=Hs.271742 ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 3 /FL=gb:NM_005485.2 gb:AF083068.1 AF083068 poly (ADP-ribose) polymerase family, member 3 PARP3 10039 NM_001003931 /// NM_001003935 /// NM_005485 /// XM_005264779 /// XM_006712914 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0051106 // positive regulation of DNA ligation // inferred from genetic interaction /// 0060236 // regulation of mitotic spindle organization // inferred from mutant phenotype /// 1990166 // protein localization to site of double-strand break // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 209941_at U50062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U50062.1 /DEF=Homo sapiens RIP protein kinase mRNA, complete cds. /FEA=mRNA /PROD=RIP protein kinase /DB_XREF=gi:3426026 /UG=Hs.296327 receptor (TNFRSF)-interacting serine-threonine kinase 1 /FL=gb:U50062.1 gb:NM_003804.1 U50062 receptor (TNFRSF)-interacting serine-threonine kinase 1 RIPK1 8737 NM_003804 /// XM_005249457 /// XM_005249458 /// XM_006715236 /// XM_006715237 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred by curator /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036289 // peptidyl-serine autophosphorylation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043068 // positive regulation of programmed cell death // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044257 // cellular protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from mutant phenotype /// 0060545 // positive regulation of necroptotic process // inferred from mutant phenotype /// 0070231 // T cell apoptotic process // inferred from sequence or structural similarity /// 0070266 // necroptotic process // inferred from mutant phenotype /// 0070926 // regulation of ATP:ADP antiporter activity // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097343 // ripoptosome assembly // inferred from mutant phenotype /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 0097527 // necroptotic signaling pathway // inferred from sequence or structural similarity /// 1990000 // amyloid fibril formation // inferred from mutant phenotype /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005123 // death receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction 209942_x_at BC000340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000340.1 /DEF=Homo sapiens, melanoma antigen, family A, 3, clone MGC:8564, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 3 /DB_XREF=gi:12653144 /UG=Hs.36978 melanoma antigen, family A, 3 /FL=gb:BC000340.1 gb:NM_005362.1 BC000340 melanoma antigen family A, 3 /// melanoma antigen family A, 6 MAGEA3 /// MAGEA6 4102 /// 4105 NM_005362 /// NM_005363 /// NM_175868 /// XM_005274676 /// XM_006724818 0005515 // protein binding // inferred from physical interaction 209943_at AF176699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF176699.1 /DEF=Homo sapiens F-box protein FBL4 mRNA, complete cds. /FEA=mRNA /PROD=F-box protein FBL4 /DB_XREF=gi:6103636 /UG=Hs.49526 f-box and leucine-rich repeat protein 4 /FL=gb:AF176699.1 gb:AF199355.1 gb:NM_012160.1 AF176699 F-box and leucine-rich repeat protein 4 FBXL4 26235 NM_001278716 /// NM_012160 /// NR_103836 /// NR_103837 /// XM_005266930 /// XM_006715458 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 209944_at BC000330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000330.1 /DEF=Homo sapiens, Similar to clones 23667 and 23775 zinc finger protein, clone MGC:8520, mRNA, complete cds. /FEA=mRNA /PROD=Similar to clones 23667 and 23775 zinc fingerprotein /DB_XREF=gi:12653126 /UG=Hs.7137 clones 23667 and 23775 zinc finger protein /FL=gb:BC000330.1 gb:BC004357.1 BC000330 prostaglandin reductase 2 /// zinc finger protein 410 PTGR2 /// ZNF410 57862 /// 145482 NM_001146154 /// NM_001146155 /// NM_001242924 /// NM_001242926 /// NM_001242927 /// NM_001242928 /// NM_021188 /// NM_152444 /// NR_040251 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0036132 // 13-prostaglandin reductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047522 // 15-oxoprostaglandin 13-oxidase activity // inferred from direct assay 209945_s_at BC000251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000251.1 /DEF=Homo sapiens, Similar to glycogen synthase kinase 3 beta, clone MGC:1736, mRNA, complete cds. /FEA=mRNA /PROD=Similar to glycogen synthase kinase 3 beta /DB_XREF=gi:12652980 /UG=Hs.78802 glycogen synthase kinase 3 beta /FL=gb:BC000251.1 BC000251 glycogen synthase kinase 3 beta GSK3B 2932 NM_001146156 /// NM_002093 /// XM_006713610 /// XM_006713611 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from mutant phenotype /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from direct assay /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from direct assay /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0021766 // hippocampus development // inferred from mutant phenotype /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031333 // negative regulation of protein complex assembly // inferred from mutant phenotype /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0035372 // protein localization to microtubule // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036016 // cellular response to interleukin-3 // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044027 // hypermethylation of CpG island // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045719 // negative regulation of glycogen biosynthetic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050774 // negative regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0071109 // superior temporal gyrus development // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2000077 // negative regulation of type B pancreatic cell development // traceable author statement /// 2000466 // negative regulation of glycogen (starch) synthase activity // traceable author statement /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0030877 // beta-catenin destruction complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from direct assay /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0048156 // tau protein binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 209946_at U58111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58111.1 /DEF=Human FLT4 ligand mRNA, complete cds. /FEA=mRNA /PROD=FLT4 ligand DHM /DB_XREF=gi:1373426 /UG=Hs.79141 vascular endothelial growth factor C /FL=gb:U43142.1 gb:U58111.1 gb:NM_005429.1 U58111 vascular endothelial growth factor C VEGFC 7424 NM_005429 0001525 // angiogenesis // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006929 // substrate-dependent cell migration // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 1901492 // positive regulation of lymphangiogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0043185 // vascular endothelial growth factor receptor 3 binding // inferred from electronic annotation 209947_at BC003170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003170.1 /DEF=Homo sapiens, KIAA0144 gene product, clone MGC:4404, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0144 gene product /DB_XREF=gi:13111994 /UG=Hs.8127 KIAA0144 gene product /FL=gb:BC003170.1 BC003170 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 209948_at U61536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U61536.1 /DEF=Human potassium channel beta subunit mRNA, complete cds. /FEA=mRNA /PROD=potassium channel beta subunit /DB_XREF=gi:2209016 /UG=Hs.93841 potassium large conductance calcium-activated channel, subfamily M, beta member 1 /FL=gb:U38907.1 gb:U25138.1 gb:U42600.1 gb:U61536.1 gb:AF026002.1 gb:NM_004137.1 U61536 potassium large conductance calcium-activated channel, subfamily M, beta member 1 KCNMB1 3779 NM_004137 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015269 // calcium-activated potassium channel activity // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from electronic annotation 209949_at BC001606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001606.1 /DEF=Homo sapiens, Similar to neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2), clone MGC:2275, mRNA, complete cds. /FEA=mRNA /PROD=Similar to neutrophil cytosolic factor 2 (65kD,chronic granulomatous disease, autosomal 2) /DB_XREF=gi:12804408 /UG=Hs.949 neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) /FL=gb:BC001606.1 gb:M32011.1 gb:NM_000433.1 BC001606 neutrophil cytosolic factor 2 NCF2 4688 NM_000433 /// NM_001127651 /// NM_001190789 /// NM_001190794 /// XM_005245207 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // traceable author statement /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032010 // phagolysosome // traceable author statement /// 0043020 // NADPH oxidase complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from electronic annotation 209950_s_at BC004300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004300.1 /DEF=Homo sapiens, Similar to villin-like, clone MGC:10896, mRNA, complete cds. /FEA=mRNA /PROD=Similar to villin-like /DB_XREF=gi:13279166 /UG=Hs.103665 villin-like /FL=gb:BC004300.1 BC004300 villin-like VILL 50853 NM_015873 /// XM_005265191 /// XM_005265192 /// XM_006713183 /// XM_006713184 /// XM_006713185 /// XR_245137 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation 0015629 // actin cytoskeleton // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 209951_s_at AW007458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007458 /FEA=EST /DB_XREF=gi:5856236 /DB_XREF=est:ws52a09.x1 /CLONE=IMAGE:2500792 /UG=Hs.110299 mitogen-activated protein kinase kinase 7 /FL=gb:AF014401.1 gb:AF022805.1 gb:AF006689.1 gb:AF013588.1 gb:NM_005043.1 AW007458 mitogen-activated protein kinase kinase 7 MAP2K7 5609 NM_145185 /// XM_005272489 /// XM_005272490 /// XM_006722800 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from sequence or structural similarity /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209952_s_at AF006689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006689.1 /DEF=Homo sapiens MAP kinase kinase Jnkk2 mRNA, complete cds. /FEA=mRNA /PROD=Jnkk2 /DB_XREF=gi:2811125 /UG=Hs.110299 mitogen-activated protein kinase kinase 7 /FL=gb:AF014401.1 gb:AF022805.1 gb:AF006689.1 gb:AF013588.1 gb:NM_005043.1 AF006689 mitogen-activated protein kinase kinase 7 MAP2K7 5609 NM_145185 /// XM_005272489 /// XM_005272490 /// XM_006722800 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from sequence or structural similarity /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209953_s_at U63131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63131.1 /DEF=Human CDC37 homolog mRNA, complete cds. /FEA=mRNA /PROD=CDC37 homolog /DB_XREF=gi:1421820 /UG=Hs.160958 CDC37 (cell division cycle 37, S. cerevisiae, homolog) /FL=gb:BC000083.1 gb:U43077.1 gb:U63131.1 gb:NM_007065.1 U63131 cell division cycle 37 CDC37 11140 NM_007065 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0006605 // protein targeting // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // inferred from mutant phenotype /// 0060338 // regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from electronic annotation 209954_x_at AF343880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF343880.1 /DEF=Homo sapiens SYT variant 1 mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=SYT variant 1 /DB_XREF=gi:13384207 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 /FL=gb:AF343880.1 AF343880 synovial sarcoma translocation, chromosome 18 SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 209955_s_at U76833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U76833.1 /DEF=Human integral membrane serine protease Seprase mRNA, complete cds. /FEA=mRNA /PROD=integral membrane serine protease Seprase /DB_XREF=gi:1924981 /UG=Hs.418 fibroblast activation protein, alpha /FL=gb:U09278.1 gb:U76833.1 gb:NM_004460.1 U76833 fibroblast activation protein, alpha FAP 2191 NM_001291807 /// NM_004460 0006508 // proteolysis // inferred from electronic annotation /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay /// 0051917 // regulation of fibrinolysis // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071438 // invadopodium membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // non-traceable author statement /// 0008239 // dipeptidyl-peptidase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // non-traceable author statement 209956_s_at U23460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U23460.1 /DEF=Human proline rich calmodulin-dependent protein kinase mRNA, complete cds. /FEA=mRNA /PROD=proline rich calmodulin-dependent proteinkinase /DB_XREF=gi:4096107 /UG=Hs.4884 calciumcalmodulin-dependent protein kinase (CaM kinase) II beta /FL=gb:U23460.1 U23460 calcium/calmodulin-dependent protein kinase II beta CAMK2B 816 NM_001220 /// NM_001293170 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 /// XM_005249859 /// XM_005249861 /// XM_005249862 /// XM_005249864 /// XM_006715776 /// XM_006715777 /// XM_006715778 /// XM_006715779 /// XM_006715780 /// XM_006715781 /// XM_006715782 /// XM_006715783 /// XM_006715784 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0002030 // inhibitory G-protein coupled receptor phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032222 // regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051823 // regulation of synapse structural plasticity // traceable author statement /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060466 // activation of meiosis involved in egg activation // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // traceable author statement /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 209957_s_at M30262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30262.1 /DEF=Human cardiodilatin-atrial natriuretic factor (CDD-ANF) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180181 /UG=Hs.75640 natriuretic peptide precursor A /FL=gb:M30262.1 M30262 natriuretic peptide A NPPA 4878 NM_006172 0001666 // response to hypoxia // inferred from electronic annotation /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from sequence or structural similarity /// 0008217 // regulation of blood pressure // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 209958_s_at AF095771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF095771.1 /DEF=Homo sapiens PTH-responsive osteosarcoma B1 protein (B1) mRNA, complete cds. /FEA=mRNA /GEN=B1 /PROD=PTH-responsive osteosarcoma B1 protein /DB_XREF=gi:4588086 /UG=Hs.79340 PTH-responsive osteosarcoma B1 protein /FL=gb:AF095771.1 AF095771 Bardet-Biedl syndrome 9 BBS9 27241 NM_001033604 /// NM_001033605 /// NM_014451 /// NM_198428 /// XM_005249700 /// XM_005249701 /// XM_006715687 /// XM_006715688 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209959_at U12767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U12767.1 /DEF=Human mitogen induced nuclear orphan receptor (MINOR) mRNA, complete cds. /FEA=mRNA /GEN=MINOR /PROD=mitogen induced nuclear orphan receptor /DB_XREF=gi:924281 /UG=Hs.80561 nuclear receptor subfamily 4, group A, member 3 /FL=gb:U12767.1 U12767 nuclear receptor subfamily 4, group A, member 3 NR4A3 8013 NM_006981 /// NM_173198 /// NM_173199 /// NM_173200 /// XM_005252237 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060005 // vestibular reflex // inferred from electronic annotation /// 2000108 // positive regulation of leukocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209960_at X16323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16323.1 /DEF=Human mRNA for hepatocyte growth factor (HGF). /FEA=mRNA /DB_XREF=gi:32081 /UG=Hs.809 hepatocyte growth factor (hepapoietin A; scatter factor) /FL=gb:M60718.1 gb:M29145.1 gb:M73239.1 gb:M73240.1 X16323 hepatocyte growth factor (hepapoietin A; scatter factor) HGF 3082 NM_000601 /// NM_001010931 /// NM_001010932 /// NM_001010933 /// NM_001010934 /// XM_006715956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209961_s_at M60718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60718.1 /DEF=Human hepatocyte growth factor mRNA, complete cds. /FEA=mRNA /GEN=HGF /PROD=hepatocyte growth factor /DB_XREF=gi:184031 /UG=Hs.809 hepatocyte growth factor (hepapoietin A; scatter factor) /FL=gb:M60718.1 gb:M29145.1 gb:M73239.1 gb:M73240.1 M60718 hepatocyte growth factor (hepapoietin A; scatter factor) HGF 3082 NM_000601 /// NM_001010931 /// NM_001010932 /// NM_001010933 /// NM_001010934 /// XM_006715956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 209962_at M34986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34986.1 /DEF=Human erythropoietin receptor mRNA, complete cds. /FEA=mRNA /GEN=EPOR /DB_XREF=gi:182200 /UG=Hs.89548 erythropoietin receptor /FL=gb:M34986.1 gb:M60459.1 gb:NM_000121.2 M34986 erythropoietin receptor EPOR 2057 NM_000121 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 209963_s_at M34986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34986.1 /DEF=Human erythropoietin receptor mRNA, complete cds. /FEA=mRNA /GEN=EPOR /DB_XREF=gi:182200 /UG=Hs.89548 erythropoietin receptor /FL=gb:M34986.1 gb:M60459.1 gb:NM_000121.2 M34986 erythropoietin receptor EPOR 2057 NM_000121 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 209964_s_at AF032105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF032105.1 /DEF=Homo sapiens ataxin-7 (SCA7) mRNA, complete cds. /FEA=mRNA /GEN=SCA7 /PROD=ataxin-7 /DB_XREF=gi:3192953 /UG=Hs.108447 spinocerebellar ataxia 7 (olivopontocerebellar atrophy with retinal degeneration) /FL=gb:AF032105.1 AF032105 ataxin 7 ATXN7 6314 NM_000333 /// NM_001128149 /// NM_001177387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006997 // nucleus organization // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 209965_s_at AB016223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016223.1 /DEF=Homo sapiens TRAD-d1 mRNA, complete cds. /FEA=mRNA /GEN=TRAD-d1 /DB_XREF=gi:3327885 /UG=Hs.125244 RAD51 (S. cerevisiae)-like 3 /FL=gb:AF034956.1 gb:AB016223.1 gb:NM_002878.1 AB016223 RAD51 paralog D RAD51D 5892 NM_001142571 /// NM_002878 /// NM_133627 /// NM_133628 /// NM_133629 /// NM_133630 /// NR_037711 /// NR_037712 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0042148 // strand invasion // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043015 // gamma-tubulin binding // inferred from direct assay 209966_x_at AF094518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF094518.1 /DEF=Homo sapiens nuclear receptor ERRG2 (ERRG2) mRNA, complete cds. /FEA=mRNA /GEN=ERRG2 /PROD=nuclear receptor ERRG2 /DB_XREF=gi:4092074 /UG=Hs.151017 estrogen-related receptor gamma /FL=gb:AF094518.1 gb:AB020639.1 AF094518 estrogen-related receptor gamma ESRRG 2104 NM_001134285 /// NM_001243505 /// NM_001243506 /// NM_001243507 /// NM_001243509 /// NM_001243510 /// NM_001243511 /// NM_001243512 /// NM_001243513 /// NM_001243514 /// NM_001243515 /// NM_001243518 /// NM_001243519 /// NM_001438 /// NM_206594 /// NM_206595 /// XM_006711203 /// XM_006711204 /// XM_006711205 /// XM_006711206 /// XM_006711207 /// XM_006711208 /// XM_006711209 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050682 // AF-2 domain binding // inferred from sequence or structural similarity 209967_s_at D14826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D14826.1 /DEF=Human mRNA for hCREM (cyclic AMP-responsive element modulator) type 2 protein, complete cds. /FEA=mRNA /GEN=hCREM-2; hCREM-2; hCREM-2; hCREM-2 /PROD=hCREM 2beta-b protein; hCREM 2beta-a protein; hCREM 2alpha-b protein; hCREM 2alpha-a protein /DB_XREF=gi:532036 /UG=Hs.155924 cAMP responsive element modulator /FL=gb:AF069065.1 gb:D14826.1 D14826 cAMP responsive element modulator CREM 1390 NM_001267562 /// NM_001267563 /// NM_001267564 /// NM_001267565 /// NM_001267566 /// NM_001267567 /// NM_001267568 /// NM_001267569 /// NM_001267570 /// NM_001881 /// NM_181571 /// NM_182717 /// NM_182718 /// NM_182719 /// NM_182720 /// NM_182721 /// NM_182722 /// NM_182723 /// NM_182724 /// NM_182725 /// NM_182769 /// NM_182770 /// NM_182771 /// NM_182772 /// NM_182850 /// NM_182853 /// NM_183011 /// NM_183012 /// NM_183013 /// NM_183060 /// NR_051971 /// NR_051972 /// NR_051973 /// NR_051974 /// NR_051975 /// XM_006717378 /// XM_006717379 /// XM_006717380 /// XM_006717381 /// XM_006717382 /// XM_006717383 /// XM_006717384 /// XM_006717385 /// XM_006717386 /// XM_006717387 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209968_s_at U63041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63041.1 /DEF=Human neural cell adhesion molecule CD56 mRNA, complete cds. /FEA=mRNA /PROD=neural cell adhesion molecule CD56 /DB_XREF=gi:1439612 /UG=Hs.167988 neural cell adhesion molecule 1 /FL=gb:NM_000615.1 gb:U63041.1 U63041 neural cell adhesion molecule 1 NCAM1 4684 NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351 0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 209969_s_at BC002704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002704.1 /DEF=Homo sapiens, Similar to signal transducer and activator of transcription 1, 91kD, clone MGC:3493, mRNA, complete cds. /FEA=mRNA /PROD=Similar to signal transducer and activator oftranscription 1, 91kD /DB_XREF=gi:12803734 /UG=Hs.21486 signal transducer and activator of transcription 1, 91kD /FL=gb:BC002704.1 BC002704 signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 209970_x_at M87507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M87507.1 /DEF=Homo sapien interleukin-1 beta convertase (IL1BCE) mRNA, complete cds. /FEA=mRNA /GEN=IL1BCE /PROD=interleukin 1-beta convertase /DB_XREF=gi:435598 /UG=Hs.2490 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) /FL=gb:M87507.1 M87507 caspase 1, apoptosis-related cysteine peptidase CASP1 834 NM_001223 /// NM_001257118 /// NM_001257119 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 /// XM_006718924 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0051882 // mitochondrial depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070269 // pyroptosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0097194 // execution phase of apoptosis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0072557 // IPAF inflammasome complex // not recorded /// 0072557 // IPAF inflammasome complex // inferred from sequence or structural similarity /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 209971_x_at AI928526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI928526 /FEA=EST /DB_XREF=gi:5664490 /DB_XREF=est:wp59a06.x1 /CLONE=IMAGE:2466034 /UG=Hs.258730 heme-regulated initiation factor 2-alpha kinase /FL=gb:AF116615.1 AI928526 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 AIMP2 7965 NM_006303 /// XM_005249847 /// XM_005249848 /// XM_005249850 /// XM_006715772 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 209972_s_at AF116615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116615.1 /DEF=Homo sapiens PRO0992 mRNA, complete cds. /FEA=mRNA /PROD=PRO0992 /DB_XREF=gi:7959732 /UG=Hs.258730 heme-regulated initiation factor 2-alpha kinase /FL=gb:AF116615.1 AF116615 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 AIMP2 7965 NM_006303 /// XM_005249847 /// XM_005249848 /// XM_005249850 /// XM_006715772 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 209973_at AF097419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF097419.1 /DEF=Homo sapiens 10IHW 9022 IkBL protein (NFKBIL1) mRNA, NFKBIL1-+738T allele, complete cds. /FEA=mRNA /GEN=NFKBIL1 /PROD=IkBL protein /DB_XREF=gi:5031194 /UG=Hs.2764 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 /FL=gb:NM_005007.1 gb:AF097419.1 gb:AF097420.1 gb:AF097421.1 gb:AF097422.1 gb:AF097423.1 gb:AF097424.1 gb:AF097425.1 gb:AF097426.1 gb:AF097427.1 gb:AF097428.1 gb:AF097429.1 AF097419 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 NFKBIL1 4795 NM_001144961 /// NM_001144962 /// NM_001144963 /// NM_005007 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 209974_s_at AF047473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047473.1 /DEF=Homo sapiens testis mitotic checkpoint BUB3 (BUB3) mRNA, complete cds. /FEA=mRNA /GEN=BUB3 /PROD=testis mitotic checkpoint BUB3 /DB_XREF=gi:3378103 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:AF047473.1 AF047473 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 209975_at AF182276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182276.1 /DEF=Homo sapiens cytochrome P450-2E1 (CYP2E1) mRNA, complete cds. /FEA=mRNA /GEN=CYP2E1 /PROD=cytochrome P450-2E1 /DB_XREF=gi:6470140 /UG=Hs.75183 cytochrome P450, subfamily IIE (ethanol-inducible) /FL=gb:NM_000773.2 gb:J02625.1 gb:AF182276.1 AF182276 cytochrome P450, family 2, subfamily E, polypeptide 1 CYP2E1 1571 NM_000773 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0010193 // response to ozone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 209976_s_at AF182276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182276.1 /DEF=Homo sapiens cytochrome P450-2E1 (CYP2E1) mRNA, complete cds. /FEA=mRNA /GEN=CYP2E1 /PROD=cytochrome P450-2E1 /DB_XREF=gi:6470140 /UG=Hs.75183 cytochrome P450, subfamily IIE (ethanol-inducible) /FL=gb:NM_000773.2 gb:J02625.1 gb:AF182276.1 AF182276 cytochrome P450, family 2, subfamily E, polypeptide 1 CYP2E1 1571 NM_000773 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0010193 // response to ozone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 209977_at M74220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74220.1 /DEF=Human plasminogen mRNA, complete cds. /FEA=mRNA /PROD=plasminogen /DB_XREF=gi:190025 /UG=Hs.75576 plasminogen /FL=gb:M74220.1 gb:NM_000301.1 M74220 plasminogen PLG 5340 NM_000301 /// NM_001168338 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0022617 // extracellular matrix disassembly // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0071674 // mononuclear cell migration // inferred from electronic annotation /// 2000048 // negative regulation of cell-cell adhesion mediated by cadherin // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction 209978_s_at M74220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74220.1 /DEF=Human plasminogen mRNA, complete cds. /FEA=mRNA /PROD=plasminogen /DB_XREF=gi:190025 /UG=Hs.75576 plasminogen /FL=gb:M74220.1 gb:NM_000301.1 M74220 lipoprotein, Lp(a) /// plasminogen LPA /// PLG 4018 /// 5340 NM_000301 /// NM_001168338 /// NM_005577 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0022617 // extracellular matrix disassembly // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0071674 // mononuclear cell migration // inferred from electronic annotation /// 2000048 // negative regulation of cell-cell adhesion mediated by cadherin // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from direct assay /// 0034358 // plasma lipoprotein particle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction 209979_at AF001042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001042.1 /DEF=Homo sapiens RNA editase (RED1) mRNA, complete cds. /FEA=mRNA /GEN=RED1 /PROD=RNA editase /DB_XREF=gi:2114492 /UG=Hs.85302 adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) /FL=gb:AF001042.1 AF001042 adenosine deaminase, RNA-specific, B1 ADARB1 104 NM_001033049 /// NM_001112 /// NM_001160230 /// NM_015833 /// NM_015834 /// NR_027672 /// NR_027673 /// NR_027674 /// NR_073200 /// XM_006723953 /// XM_006723954 /// XM_006723955 /// XM_006723956 /// XM_006723957 /// XM_006723958 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred by curator /// 0016556 // mRNA modification // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 209980_s_at L23928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23928.1 /DEF=Homo sapiens serine hydroxymethyltransferase mRNA, complete cds. /FEA=mRNA /GEN=SHMT; SHMT; SHMT /PROD=serine hydroxymethyltransferase; serine hydroxymethyltransferase; serine hydroxymethyltransferase /DB_XREF=gi:438633 /UG=Hs.8889 serine hydroxymethyltransferase 1 (soluble) /FL=gb:L11931.1 gb:L23928.1 gb:NM_004169.1 L23928 microRNA 6778 /// serine hydroxymethyltransferase 1 (soluble) MIR6778 /// SHMT1 6470 /// 102466733 NM_001281786 /// NM_004169 /// NM_148918 /// NR_106836 /// XM_005256767 0006508 // proteolysis // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006565 // L-serine catabolic process // inferred from direct assay /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from direct assay /// 0019264 // glycine biosynthetic process from serine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from direct assay /// 0046655 // folic acid metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004372 // glycine hydroxymethyltransferase activity // inferred from direct assay /// 0004372 // glycine hydroxymethyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0008732 // L-allo-threonine aldolase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 209981_at AL023553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023553 /DEF=Human DNA sequence from clone RP3-347H13 on chromosome 22 Contains the 3 end of the ACO2 gene for mitochondrial aconitase 2, the gene for a novel protein similar to yeast DNA-directed RNA Polymerase III 25 kD Polypeptide, the gene for the human ... /FEA=mRNA_3 /DB_XREF=gi:4490860 /UG=Hs.106635 ortholog of rat pippin /FL=gb:AB027011.1 AL023553 cold shock domain containing C2, RNA binding CSDC2 27254 NM_014460 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006398 // histone mRNA 3'-end processing // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement 209982_s_at AA608820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA608820 /FEA=EST /DB_XREF=gi:2457248 /DB_XREF=est:af03g01.s1 /CLONE=IMAGE:1030608 /UG=Hs.124085 KIAA0921 protein /FL=gb:AB035266.1 AA608820 neurexin 2 NRXN2 9379 NM_015080 /// NM_138732 /// NM_138734 /// XM_005274400 /// XM_005274401 /// XM_005274402 /// XM_005274406 /// XM_006718742 /// XM_006718743 /// XM_006718744 /// XM_006718745 /// XM_006718746 /// XM_006718747 /// XM_006718748 /// XM_006718749 /// XR_428930 /// XR_428931 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0042297 // vocal learning // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097116 // gephyrin clustering // inferred from sequence or structural similarity /// 0097118 // neuroligin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005246 // calcium channel regulator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // traceable author statement /// 0097109 // neuroligin family protein binding // inferred from sequence or structural similarity /// 0097109 // neuroligin family protein binding // traceable author statement 209983_s_at AB035266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035266.1 /DEF=Homo sapiens mRNA for neurexin II, complete cds. /FEA=mRNA /GEN=NEUREXIN II /PROD=neurexin II /DB_XREF=gi:7416826 /UG=Hs.124085 KIAA0921 protein /FL=gb:AB035266.1 AB035266 neurexin 2 NRXN2 9379 NM_015080 /// NM_138732 /// NM_138734 /// XM_005274400 /// XM_005274401 /// XM_005274402 /// XM_005274406 /// XM_006718742 /// XM_006718743 /// XM_006718744 /// XM_006718745 /// XM_006718746 /// XM_006718747 /// XM_006718748 /// XM_006718749 /// XR_428930 /// XR_428931 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0042297 // vocal learning // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097116 // gephyrin clustering // inferred from sequence or structural similarity /// 0097118 // neuroligin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005246 // calcium channel regulator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // traceable author statement /// 0097109 // neuroligin family protein binding // inferred from sequence or structural similarity /// 0097109 // neuroligin family protein binding // traceable author statement 209984_at AB037901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB037901.1 /DEF=Homo sapiens GASC-1 mRNA, complete cds. /FEA=mRNA /GEN=GASC-1 /DB_XREF=gi:10567163 /UG=Hs.149918 gene amplified in squamous cell carcinoma 1; KIAA0780 protein /FL=gb:AB037901.1 AB037901 lysine (K)-specific demethylase 4C KDM4C 23081 NM_001146694 /// NM_001146695 /// NM_001146696 /// NM_015061 /// XM_006716741 /// XR_428422 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0033169 // histone H3-K9 demethylation // inferred from mutant phenotype /// 0046417 // chorismate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051213 // dioxygenase activity // inferred from electronic annotation 209985_s_at BE797438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE797438 /FEA=EST /DB_XREF=gi:10218636 /DB_XREF=est:601587753F1 /CLONE=IMAGE:3941868 /UG=Hs.1619 achaete-scute complex (Drosophila) homolog-like 1 /FL=gb:BC002341.1 gb:BC001638.1 gb:BC003134.1 gb:BC004425.1 gb:L08424.1 gb:NM_004316.1 BE797438 achaete-scute family bHLH transcription factor 1 ASCL1 429 NM_004316 0001764 // neuron migration // inferred from electronic annotation /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0003359 // noradrenergic neuron fate commitment // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007400 // neuroblast fate determination // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021779 // oligodendrocyte cell fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from expression pattern /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // non-traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060163 // subpallium neuron fate commitment // inferred from electronic annotation /// 0060165 // regulation of timing of subpallium neuron differentiation // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // non-traceable author statement /// 0060579 // ventral spinal cord interneuron fate commitment // inferred from sequence or structural similarity /// 0061100 // lung neuroendocrine cell differentiation // inferred from electronic annotation /// 0061102 // stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061103 // carotid body glomus cell differentiation // inferred from electronic annotation /// 0061104 // adrenal chromaffin cell differentiation // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070849 // response to epidermal growth factor // inferred from electronic annotation /// 0071259 // cellular response to magnetism // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 209986_at BC002341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002341.1 /DEF=Homo sapiens, Similar to achaete-scute complex (Drosophila) homolog-like 1, clone MGC:8434, mRNA, complete cds. /FEA=mRNA /PROD=Similar to achaete-scute complex (Drosophila)homolog-like 1 /DB_XREF=gi:12803078 /UG=Hs.1619 achaete-scute complex (Drosophila) homolog-like 1 /FL=gb:BC002341.1 gb:BC001638.1 gb:BC003134.1 gb:BC004425.1 gb:L08424.1 gb:NM_004316.1 BC002341 uncharacterized LOC101929036 /// phenylalanine hydroxylase LOC101929036 /// PAH 5053 /// 101929036 NM_000277 /// XR_246028 /// XR_253108 /// XR_424391 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // non-traceable author statement /// 0042423 // catecholamine biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004505 // phenylalanine 4-monooxygenase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016714 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209987_s_at BC002341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002341.1 /DEF=Homo sapiens, Similar to achaete-scute complex (Drosophila) homolog-like 1, clone MGC:8434, mRNA, complete cds. /FEA=mRNA /PROD=Similar to achaete-scute complex (Drosophila)homolog-like 1 /DB_XREF=gi:12803078 /UG=Hs.1619 achaete-scute complex (Drosophila) homolog-like 1 /FL=gb:BC002341.1 gb:BC001638.1 gb:BC003134.1 gb:BC004425.1 gb:L08424.1 gb:NM_004316.1 BC002341 achaete-scute family bHLH transcription factor 1 ASCL1 429 NM_004316 0001764 // neuron migration // inferred from electronic annotation /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0003359 // noradrenergic neuron fate commitment // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007400 // neuroblast fate determination // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021779 // oligodendrocyte cell fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from expression pattern /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // non-traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060163 // subpallium neuron fate commitment // inferred from electronic annotation /// 0060165 // regulation of timing of subpallium neuron differentiation // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // non-traceable author statement /// 0060579 // ventral spinal cord interneuron fate commitment // inferred from sequence or structural similarity /// 0061100 // lung neuroendocrine cell differentiation // inferred from electronic annotation /// 0061102 // stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061103 // carotid body glomus cell differentiation // inferred from electronic annotation /// 0061104 // adrenal chromaffin cell differentiation // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070849 // response to epidermal growth factor // inferred from electronic annotation /// 0071259 // cellular response to magnetism // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 209988_s_at BC001638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001638.1 /DEF=Homo sapiens, Similar to achaete-scute complex (Drosophila) homolog-like 1, clone MGC:1532, mRNA, complete cds. /FEA=mRNA /PROD=Similar to achaete-scute complex (Drosophila)homolog-like 1 /DB_XREF=gi:12804462 /UG=Hs.1619 achaete-scute complex (Drosophila) homolog-like 1 /FL=gb:BC002341.1 gb:BC001638.1 gb:BC003134.1 gb:BC004425.1 gb:L08424.1 gb:NM_004316.1 BC001638 achaete-scute family bHLH transcription factor 1 ASCL1 429 NM_004316 0001764 // neuron migration // inferred from electronic annotation /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0003359 // noradrenergic neuron fate commitment // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007400 // neuroblast fate determination // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021779 // oligodendrocyte cell fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from expression pattern /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // non-traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060163 // subpallium neuron fate commitment // inferred from electronic annotation /// 0060165 // regulation of timing of subpallium neuron differentiation // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // non-traceable author statement /// 0060579 // ventral spinal cord interneuron fate commitment // inferred from sequence or structural similarity /// 0061100 // lung neuroendocrine cell differentiation // inferred from electronic annotation /// 0061102 // stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061103 // carotid body glomus cell differentiation // inferred from electronic annotation /// 0061104 // adrenal chromaffin cell differentiation // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070849 // response to epidermal growth factor // inferred from electronic annotation /// 0071259 // cellular response to magnetism // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 209989_at AF317549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF317549.1 /DEF=Homo sapiens zinc finger protein 268 (ZNF268) mRNA, complete cds. /FEA=mRNA /GEN=ZNF268 /PROD=zinc finger protein 268 /DB_XREF=gi:12584158 /UG=Hs.183291 zinc finger protein 268 /FL=gb:AF317549.1 AF317549 zinc finger protein 268 ZNF268 10795 NM_001165881 /// NM_001165882 /// NM_001165883 /// NM_001165884 /// NM_001165885 /// NM_001165886 /// NM_001165887 /// NM_003415 /// NM_152943 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008588 // release of cytoplasmic sequestered NF-kappaB // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046022 // positive regulation of transcription from RNA polymerase II promoter during mitosis // inferred from mutant phenotype /// 0071157 // negative regulation of cell cycle arrest // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 209990_s_at AF056085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF056085.1 /DEF=Homo sapiens GABA-B receptor mRNA, complete cds. /FEA=mRNA /PROD=GABA-B receptor /DB_XREF=gi:3719225 /UG=Hs.198612 G protein-coupled receptor 51 /FL=gb:AF056085.1 gb:AF069755.1 gb:AF074483.1 gb:NM_005458.1 gb:AF099033.1 AF056085 gamma-aminobutyric acid (GABA) B receptor, 2 GABBR2 9568 NM_005458 /// XM_005252316 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209991_x_at AF069755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF069755.1 /DEF=Homo sapiens orphan G protein-coupled receptor HG20 (HG20) mRNA, complete cds. /FEA=mRNA /GEN=HG20 /PROD=orphan G protein-coupled receptor HG20 /DB_XREF=gi:4091932 /UG=Hs.198612 G protein-coupled receptor 51 /FL=gb:AF056085.1 gb:AF069755.1 gb:AF074483.1 gb:NM_005458.1 gb:AF099033.1 AF069755 gamma-aminobutyric acid (GABA) B receptor, 2 GABBR2 9568 NM_005458 /// XM_005252316 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 209992_at AB044805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044805.1 /DEF=Homo sapiens mRNA for 6-phosphofructo-2-kinase heart isoform, complete cds. /FEA=mRNA /PROD=6-phosphofructo-2-kinase heart isoform /DB_XREF=gi:11933148 /UG=Hs.211585 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 2 /FL=gb:AB044805.1 AB044805 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 PFKFB2 5208 NM_001018053 /// NM_006212 /// XM_005273162 /// XM_006711381 /// XM_006711382 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from direct assay /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 209993_at AF016535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF016535.1 /DEF=Homo sapiens P-glycoprotein (mdr1) mRNA, complete cds. /FEA=mRNA /GEN=mdr1 /PROD=P-glycoprotein /DB_XREF=gi:2353263 /UG=Hs.21330 ATP-binding cassette, sub-family B (MDRTAP), member 1 /FL=gb:M14758.1 gb:AF016535.1 gb:NM_000927.2 AF016535 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ABCB1 5243 NM_000927 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0072089 // stem cell proliferation // inferred from mutant phenotype 0000139 // Golgi membrane // /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0016324 // apical plasma membrane // /// 0046581 // intercellular canaliculus // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008559 // xenobiotic-transporting ATPase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 209994_s_at AF016535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF016535.1 /DEF=Homo sapiens P-glycoprotein (mdr1) mRNA, complete cds. /FEA=mRNA /GEN=mdr1 /PROD=P-glycoprotein /DB_XREF=gi:2353263 /UG=Hs.21330 ATP-binding cassette, sub-family B (MDRTAP), member 1 /FL=gb:M14758.1 gb:AF016535.1 gb:NM_000927.2 AF016535 ATP-binding cassette, sub-family B (MDR/TAP), member 1 /// ATP-binding cassette, sub-family B (MDR/TAP), member 4 ABCB1 /// ABCB4 5243 /// 5244 NM_000443 /// NM_000927 /// NM_018849 /// NM_018850 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0006855 // drug transmembrane transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0072089 // stem cell proliferation // inferred from mutant phenotype 0000139 // Golgi membrane // /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0016324 // apical plasma membrane // /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008559 // xenobiotic-transporting ATPase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 209995_s_at BC003574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003574.1 /DEF=Homo sapiens, T-cell leukemialymphoma 1A, clone MGC:2260, mRNA, complete cds. /FEA=mRNA /PROD=T-cell leukemialymphoma 1A /DB_XREF=gi:13097749 /UG=Hs.2484 T-cell leukemialymphoma 1A /FL=gb:NM_021966.1 gb:BC003574.1 BC003574 T-cell leukemia/lymphoma 1A TCL1A 8115 NM_001098725 /// NM_021966 /// NR_049726 0007275 // multicellular organismal development // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 209996_x_at AA931266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA931266 /FEA=EST /DB_XREF=gi:3085652 /DB_XREF=est:om88f05.s1 /CLONE=IMAGE:1554273 /UG=Hs.315478 Homo sapiens, Similar to pericentriolar material 1, clone MGC:8458, mRNA, complete cds /FL=gb:BC000453.1 AA931266 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 209997_x_at BC000453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000453.1 /DEF=Homo sapiens, Similar to pericentriolar material 1, clone MGC:8458, mRNA, complete cds. /FEA=mRNA /PROD=Similar to pericentriolar material 1 /DB_XREF=gi:12653366 /UG=Hs.315478 Homo sapiens, Similar to pericentriolar material 1, clone MGC:8458, mRNA, complete cds /FL=gb:BC000453.1 BC000453 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 209998_at BC001030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001030.1 /DEF=Homo sapiens, Similar to phosphatidylinositol glycan, class O, clone MGC:3079, mRNA, complete cds. /FEA=mRNA /PROD=Similar to phosphatidylinositol glycan, class O /DB_XREF=gi:12654408 /UG=Hs.324874 Homo sapiens, Similar to phosphatidylinositol glycan, class O, clone MGC:3079, mRNA, complete cds /FL=gb:BC001030.1 BC001030 phosphatidylinositol glycan anchor biosynthesis, class O PIGO 84720 NM_001201484 /// NM_032634 /// NM_152850 /// XM_005251619 /// XR_242515 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 209999_x_at AI056051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI056051 /FEA=EST /DB_XREF=gi:3329917 /DB_XREF=est:ox46c05.s1 /CLONE=IMAGE:1659368 /UG=Hs.50640 JAK binding protein /FL=gb:U88326.1 gb:AB005043.1 gb:AB000734.1 gb:NM_003745.1 AI056051 suppressor of cytokine signaling 1 SOCS1 8651 NM_003745 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046426 // negative regulation of JAK-STAT cascade // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction 210000_s_at U88326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U88326.1 /DEF=Human suppressor of cytokine signalling-1 (SOCS-1) mRNA, complete cds. /FEA=mRNA /GEN=SOCS-1 /PROD=suppressor of cytokine signalling-1 /DB_XREF=gi:2245383 /UG=Hs.50640 JAK binding protein /FL=gb:U88326.1 gb:AB005043.1 gb:AB000734.1 gb:NM_003745.1 U88326 suppressor of cytokine signaling 1 SOCS1 8651 NM_003745 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046426 // negative regulation of JAK-STAT cascade // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction 210001_s_at AB005043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB005043.1 /DEF=Homo sapiens mRNA for STAT induced STAT inhibitor-1, complete cds. /FEA=mRNA /PROD=STAT induced STAT inhibitor-1 /DB_XREF=gi:2443364 /UG=Hs.50640 JAK binding protein /FL=gb:U88326.1 gb:AB005043.1 gb:AB000734.1 gb:NM_003745.1 AB005043 suppressor of cytokine signaling 1 SOCS1 8651 NM_003745 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046426 // negative regulation of JAK-STAT cascade // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction 210002_at D87811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87811.1 /DEF=Homo sapiens mRNA for GATA-6, complete cds. /FEA=mRNA /PROD=GATA-6 /DB_XREF=gi:2506075 /UG=Hs.50924 GATA-binding protein 6 /FL=gb:U66075.1 gb:D87811.1 gb:NM_005257.1 D87811 GATA binding protein 6 GATA6 2627 NM_005257 /// XM_005258248 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from mutant phenotype /// 0003309 // type B pancreatic cell differentiation // inferred from electronic annotation /// 0003310 // pancreatic A cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007493 // endodermal cell fate determination // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0032911 // negative regulation of transforming growth factor beta1 production // inferred from mutant phenotype /// 0032912 // negative regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0035987 // endodermal cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from mutant phenotype /// 0051891 // positive regulation of cardioblast differentiation // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060486 // Clara cell differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation /// 0060575 // intestinal epithelial cell differentiation // inferred from direct assay /// 0060947 // cardiac vascular smooth muscle cell differentiation // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from mutant phenotype /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210004_at AF035776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035776.1 /DEF=Homo sapiens oxidized low-density lipoprotein receptor mRNA, complete cds. /FEA=mRNA /PROD=oxidized low-density lipoprotein receptor /DB_XREF=gi:3941299 /UG=Hs.77729 oxidised low density lipoprotein (lectin-like) receptor 1 /FL=gb:AB010710.1 gb:AF035776.1 gb:NM_002543.1 AF035776 oxidized low density lipoprotein (lectin-like) receptor 1 OLR1 4973 NM_001172632 /// NM_001172633 /// NM_002543 /// XM_006719081 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005041 // low-density lipoprotein receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 210005_at D32051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32051.1 /DEF=Human mRNA for GARS protein, complete cds. /FEA=mRNA /PROD=GARS protein /DB_XREF=gi:509032 /UG=Hs.82285 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase /FL=gb:D32051.1 D32051 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART 2618 NM_000819 /// NM_001136005 /// NM_001136006 /// NM_175085 /// XM_005260941 /// XM_006723988 /// XM_006723989 /// XM_006723990 0003360 // brainstem development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004637 // phosphoribosylamine-glycine ligase activity // inferred from electronic annotation /// 0004641 // phosphoribosylformylglycinamidine cyclo-ligase activity // inferred from electronic annotation /// 0004644 // phosphoribosylglycinamide formyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210006_at BC002571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002571.1 /DEF=Homo sapiens, clone MGC:2481, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2481) /DB_XREF=gi:12803488 /UG=Hs.92700 DKFZP564O243 protein /FL=gb:BC002571.1 gb:NM_015407.1 BC002571 abhydrolase domain containing 14A /// aminoacylase 1 ABHD14A /// ACY1 95 /// 25864 NM_000666 /// NM_001198895 /// NM_001198896 /// NM_001198897 /// NM_001198898 /// NM_015407 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210007_s_at U36310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36310.1 /DEF=Human glycerol-3-phosphate dehydrogenase mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=glycerol-3-phosphate dehydrogenase /DB_XREF=gi:1020314 /UG=Hs.93201 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) /FL=gb:U36310.1 U36310 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) GPD2 2820 NM_000408 /// NM_001083112 /// XM_005246469 /// XM_005246470 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0009331 // glycerol-3-phosphate dehydrogenase complex // inferred from electronic annotation 0004368 // glycerol-3-phosphate dehydrogenase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052590 // sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity // inferred from electronic annotation /// 0052591 // sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity // inferred from electronic annotation 210008_s_at AA513737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA513737 /FEA=EST /DB_XREF=gi:2252149 /DB_XREF=est:nh88d05.s1 /CLONE=IMAGE:965577 /UG=Hs.9964 mitochondrial ribosomal protein S12 /FL=gb:BC001617.1 AA513737 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210009_s_at AF229796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229796.1 /DEF=Homo sapiens golgi SNARE isoform B (GOSR2) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=GOSR2 /PROD=golgi SNARE isoform B /DB_XREF=gi:12711466 /UG=Hs.100651 golgi SNAP receptor complex member 2 /FL=gb:AF229796.1 gb:AF007548.1 gb:NM_004287.1 AF229796 golgi SNAP receptor complex member 2 GOSR2 9570 NM_001012511 /// NM_004287 /// NM_054022 /// XM_005257843 /// XM_005257844 /// XM_005257845 /// XM_006722188 /// XM_006722189 /// XM_006722190 /// XM_006722191 /// XM_006722192 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement 210010_s_at U25147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U25147.1 /DEF=Human citrate transporter protein mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=citrate transporter protein /DB_XREF=gi:950003 /UG=Hs.111024 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 /FL=gb:U25147.1 U25147 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 SLC25A1 6576 NM_001256534 /// NM_001287387 /// NM_005984 /// NR_046298 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006843 // mitochondrial citrate transport // traceable author statement /// 0015746 // citrate transport // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015137 // citrate transmembrane transporter activity // traceable author statement 210011_s_at BC000527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000527.1 /DEF=Homo sapiens, Similar to Ewing sarcoma breakpoint region 1, clone MGC:8607, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Ewing sarcoma breakpoint region 1 /DB_XREF=gi:12653510 /UG=Hs.129953 Ewing sarcoma breakpoint region 1 /FL=gb:BC000527.1 BC000527 EWS RNA-binding protein 1 EWSR1 2130 NM_001163285 /// NM_001163286 /// NM_001163287 /// NM_005243 /// NM_013986 /// XM_005261389 /// XM_005261390 /// XM_006724166 /// XM_006724167 /// XR_430403 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210012_s_at BC000527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000527.1 /DEF=Homo sapiens, Similar to Ewing sarcoma breakpoint region 1, clone MGC:8607, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Ewing sarcoma breakpoint region 1 /DB_XREF=gi:12653510 /UG=Hs.129953 Ewing sarcoma breakpoint region 1 /FL=gb:BC000527.1 BC000527 EWS RNA-binding protein 1 EWSR1 2130 NM_001163285 /// NM_001163286 /// NM_001163287 /// NM_005243 /// NM_013986 /// XM_005261389 /// XM_005261390 /// XM_006724166 /// XM_006724167 /// XR_430403 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210013_at BC005395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005395.1 /DEF=Homo sapiens, Similar to hemopexin, clone MGC:12533, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hemopexin /DB_XREF=gi:13529280 /UG=Hs.1504 hemopexin /FL=gb:NM_000613.1 gb:BC005395.1 BC005395 hemopexin HPX 3263 NM_000613 /// XM_005252883 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0015886 // heme transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0060332 // positive regulation of response to interferon-gamma // inferred from electronic annotation /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015232 // heme transporter activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210014_x_at AF023266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF023266.1 /DEF=Homo sapiens NAD+-specific isocitrate dehydrogenase beta subunit isoform B mRNA, nuclear gene encoding mitochondrial product, complete cds. /FEA=mRNA /PROD=NAD+-specific isocitrate dehydrogenase betasubunit isoform B /DB_XREF=gi:4103447 /UG=Hs.155410 isocitrate dehydrogenase 3 (NAD+) beta /FL=gb:AF023266.1 AF023266 isocitrate dehydrogenase 3 (NAD+) beta IDH3B 3420 NM_001258384 /// NM_006899 /// NM_174855 /// NM_174856 /// XM_005260716 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210015_s_at U89330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U89330.1 /DEF=Human alternatively spliced microtubule-associated protein 2 (MAP2) mRNA, complete cds. /FEA=mRNA /GEN=MAP2 /PROD=microtubule-associated protein 2 /DB_XREF=gi:1850616 /UG=Hs.167 microtubule-associated protein 2 /FL=gb:U89330.1 gb:U01828.1 gb:NM_002374.1 U89330 microtubule-associated protein 2 MAP2 4133 NM_001039538 /// NM_002374 /// NM_031845 /// NM_031846 /// NM_031847 /// XM_005246554 /// XM_005246555 /// XM_005246556 /// XM_005246557 /// XM_005246558 /// XM_005246559 /// XM_005246560 /// XM_005246561 /// XM_005246562 /// XM_005246563 /// XM_005246564 /// XM_005246565 /// XM_005246566 /// XM_005246567 /// XM_006712529 /// XM_006712530 /// XM_006712531 /// XM_006712532 /// XM_006712533 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from expression pattern /// 0031175 // neuron projection development // inferred from expression pattern /// 0048813 // dendrite morphogenesis // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0034399 // nuclear periphery // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0002162 // dystroglycan binding // inferred from physical interaction /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation 210016_at BF223003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223003 /FEA=EST /DB_XREF=gi:11130180 /DB_XREF=est:7q27c10.x1 /CLONE=IMAGE:3699474 /UG=Hs.172619 KIAA1106 protein /FL=gb:AF036943.1 BF223003 myelin transcription factor 1-like MYT1L 23040 NM_015025 /// XM_006711862 /// XM_006711863 /// XM_006711864 /// XM_006711865 /// XM_006711866 /// XM_006711867 /// XM_006711868 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210017_at AF070528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070528.1 /DEF=Homo sapiens clone 24631 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387883 /UG=Hs.180566 mucosa associated lymphoid tissue lymphoma translocation gene 1 /FL=gb:AB026118.1 AF070528 mucosa associated lymphoid tissue lymphoma translocation gene 1 MALT1 10892 NM_006785 /// NM_173844 /// XM_005266644 0001923 // B-1 B cell differentiation // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from direct assay /// 0006952 // defense response // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0009620 // response to fungus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051168 // nuclear export // inferred from direct assay /// 0051259 // protein oligomerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0032449 // CBM complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from mutant phenotype /// 0043621 // protein self-association // inferred from physical interaction 210018_x_at AB026118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026118.1 /DEF=Homo sapiens mRNA for MALT1, complete cds. /FEA=mRNA /GEN=MALT1 /PROD=MALT1 /DB_XREF=gi:5706377 /UG=Hs.180566 mucosa associated lymphoid tissue lymphoma translocation gene 1 /FL=gb:AB026118.1 AB026118 mucosa associated lymphoid tissue lymphoma translocation gene 1 MALT1 10892 NM_006785 /// NM_173844 /// XM_005266644 0001923 // B-1 B cell differentiation // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from direct assay /// 0006952 // defense response // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0009620 // response to fungus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050856 // regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051168 // nuclear export // inferred from direct assay /// 0051259 // protein oligomerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0032449 // CBM complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from mutant phenotype /// 0043621 // protein self-association // inferred from physical interaction 210019_at M36707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36707.1 /DEF=Human calmodulin-like processed pseudogene, complete cds. /FEA=mRNA /DB_XREF=gi:179878 /UG=Hs.239600 calmodulin-like 3 /FL=gb:M36707.1 gb:M58026.1 gb:NM_005185.1 M36707 calmodulin-like 3 CALML3 810 NM_005185 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210020_x_at M58026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M58026.1 /DEF=Human NB-1 mRNA, complete cds. /FEA=mRNA /GEN=NB-1 /DB_XREF=gi:189080 /UG=Hs.239600 calmodulin-like 3 /FL=gb:M36707.1 gb:M58026.1 gb:NM_005185.1 M58026 calmodulin-like 3 CALML3 810 NM_005185 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210021_s_at BC004877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004877.1 /DEF=Homo sapiens, Similar to uracil-DNA glycosylase 2, clone MGC:11071, mRNA, complete cds. /FEA=mRNA /PROD=Similar to uracil-DNA glycosylase 2 /DB_XREF=gi:13436115 /UG=Hs.3041 uracil-DNA glycosylase 2 /FL=gb:BC004877.1 BC004877 cyclin O CCNO 10309 NM_001024592 /// NM_021147 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0007049 // cell cycle // inferred from direct assay /// 0009790 // embryo development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement /// 0051301 // cell division // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0004844 // uracil DNA N-glycosylase activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation 210022_at BC004952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004952.1 /DEF=Homo sapiens, clone MGC:10882, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10882) /DB_XREF=gi:13436325 /UG=Hs.316750 Homo sapiens, clone MGC:10882, mRNA, complete cds /FL=gb:BC004952.1 BC004952 polycomb group ring finger 1 PCGF1 84759 NM_032673 /// XM_005264616 /// XM_005264617 /// XM_005264618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210023_s_at BC004952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004952.1 /DEF=Homo sapiens, clone MGC:10882, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10882) /DB_XREF=gi:13436325 /UG=Hs.316750 Homo sapiens, clone MGC:10882, mRNA, complete cds /FL=gb:BC004952.1 BC004952 polycomb group ring finger 1 PCGF1 84759 NM_032673 /// XM_005264616 /// XM_005264617 /// XM_005264618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210024_s_at AB017644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017644.1 /DEF=Homo sapiens mRNA for ubiquitin-conjugating enzyme E2, complete cds. /FEA=mRNA /GEN=UbcH9 /PROD=ubiquitin-conjugating enzyme E2 /DB_XREF=gi:4586929 /UG=Hs.4890 ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC45) /FL=gb:BC003554.1 gb:AB017644.1 gb:AF085362.1 gb:NM_006357.1 AB017644 ubiquitin-conjugating enzyme E2E 3 UBE2E3 10477 NM_001278554 /// NM_001278555 /// NM_006357 /// NM_182678 /// XM_005246244 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 210025_s_at AW205153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW205153 /FEA=EST /DB_XREF=gi:6504625 /DB_XREF=est:UI-H-BI1-aem-h-09-0-UI.s1 /CLONE=IMAGE:2720104 /UG=Hs.57973 hypothetical protein /FL=gb:AY028896.1 AW205153 caspase recruitment domain family, member 10 CARD10 29775 NM_014550 0006461 // protein complex assembly // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0032449 // CBM complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 210026_s_at AY028896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY028896.1 /DEF=Homo sapiens caspase recruitment domain protein 10 mRNA, complete cds. /FEA=mRNA /PROD=caspase recruitment domain protein 10 /DB_XREF=gi:13488606 /UG=Hs.57973 hypothetical protein /FL=gb:AY028896.1 AY028896 caspase recruitment domain family, member 10 CARD10 29775 NM_014550 0006461 // protein complex assembly // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0032449 // CBM complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 210027_s_at M80261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80261.1 /DEF=Human apurinic endonuclease (APE) mRNA, complete cds. /FEA=mRNA /GEN=APE /PROD=apurinic endonuclease /DB_XREF=gi:178742 /UG=Hs.73722 APEX nuclease (multifunctional DNA repair enzyme) /FL=gb:BC004979.1 gb:M80261.1 M80261 APEX nuclease (multifunctional DNA repair enzyme) 1 APEX1 328 NM_001244249 /// NM_001641 /// NM_080648 /// NM_080649 /// XM_005267581 /// XM_005267582 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // not recorded /// 0006281 // DNA repair // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006284 // base-excision repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from mutant phenotype /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071417 // cellular response to organonitrogen compound // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005840 // ribosome // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from direct assay /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0004521 // endoribonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // traceable author statement /// 0004844 // uracil DNA N-glycosylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from direct assay /// 0008311 // double-stranded DNA 3'-5' exodeoxyribonuclease activity // not recorded /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008408 // 3'-5' exonuclease activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016890 // site-specific endodeoxyribonuclease activity, specific for altered base // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from electronic annotation 210028_s_at AF125507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125507.1 /DEF=Homo sapiens origin recognition complex subunit 3 (ORC3) mRNA, complete cds. /FEA=mRNA /GEN=ORC3 /PROD=origin recognition complex subunit 3 /DB_XREF=gi:4337055 /UG=Hs.74420 origin recognition complex, subunit 3 (yeast homolog)-like /FL=gb:U50950.1 gb:AF125507.1 gb:AF135044.1 gb:AF093535.1 gb:AL080116.1 gb:NM_012381.1 AF125507 origin recognition complex, subunit 3 ORC3 23595 NM_001197259 /// NM_012381 /// NM_181837 /// XM_005248704 /// XM_005248705 /// XM_005248706 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210029_at M34455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34455.1 /DEF=Human interferon-gamma-inducible indoleamine 2,3-dioxygenase (IDO) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:185790 /UG=Hs.840 indoleamine-pyrrole 2,3 dioxygenase /FL=gb:M34455.1 gb:NM_002164.1 M34455 indoleamine 2,3-dioxygenase 1 IDO1 3620 NM_002164 0002534 // cytokine production involved in inflammatory response // inferred from electronic annotation /// 0002666 // positive regulation of T cell tolerance induction // inferred from electronic annotation /// 0002678 // positive regulation of chronic inflammatory response // inferred from electronic annotation /// 0002830 // positive regulation of type 2 immune response // inferred from electronic annotation /// 0006569 // tryptophan catabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032693 // negative regulation of interleukin-10 production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034276 // kynurenic acid biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0036269 // swimming behavior // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046007 // negative regulation of activated T cell proliferation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070233 // negative regulation of T cell apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation 0004833 // tryptophan 2,3-dioxygenase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0033754 // indoleamine 2,3-dioxygenase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 210030_at BC002817 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002817.1 /DEF=Homo sapiens, Similar to CG2245 gene product, clone MGC:4293, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CG2245 gene product /DB_XREF=gi:12803940 /UG=Hs.91103 Homo sapiens, Similar to CG2245 gene product, clone MGC:4293, mRNA, complete cds /FL=gb:BC002817.1 BC002817 210031_at J04132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04132.1 /DEF=Human T cell receptor zeta-chain mRNA, complete cds. /FEA=mRNA /PROD=T-cell receptor zeta chain /DB_XREF=gi:623041 /UG=Hs.97087 CD3Z antigen, zeta polypeptide (TiT3 complex) /FL=gb:NM_000734.1 gb:J04132.1 J04132 CD247 molecule CD247 919 NM_000734 /// NM_198053 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay /// 0042105 // alpha-beta T cell receptor complex // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement 210032_s_at AI651156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI651156 /FEA=EST /DB_XREF=gi:4735135 /DB_XREF=est:wa97h09.x1 /CLONE=IMAGE:2304161 /UG=Hs.158213 sperm associated antigen 6 /FL=gb:AF079363.1 gb:AL080136.1 gb:NM_012443.1 AI651156 sperm associated antigen 6 SPAG6 9576 NM_001253854 /// NM_001253855 /// NM_012443 /// NM_172242 /// XM_005252645 /// XM_005252646 0007286 // spermatid development // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 210033_s_at AF079363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF079363.1 /DEF=Homo sapiens sperm flagellar protein Repro-SA-1 mRNA, complete cds. /FEA=mRNA /PROD=sperm flagellar protein Repro-SA-1 /DB_XREF=gi:3449382 /UG=Hs.158213 sperm associated antigen 6 /FL=gb:AF079363.1 gb:AL080136.1 gb:NM_012443.1 AF079363 sperm associated antigen 6 SPAG6 9576 NM_001253854 /// NM_001253855 /// NM_012443 /// NM_172242 /// XM_005252645 /// XM_005252646 0007286 // spermatid development // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 210034_s_at AA582460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA582460 /FEA=EST /DB_XREF=gi:2359820 /DB_XREF=est:nn54e07.s1 /CLONE=IMAGE:1087716 /UG=Hs.180946 ribosomal protein L5 /FL=gb:U66589.1 AA582460 ribosomal protein L5 /// small nucleolar RNA, C/D box 21 RPL5 /// SNORD21 6083 /// 6125 NM_000969 /// NR_000006 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210035_s_at U66589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66589.1 /DEF=Human ribosomal protein L5 pseudogene mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L5 /DB_XREF=gi:1575566 /UG=Hs.180946 ribosomal protein L5 /FL=gb:U66589.1 U66589 ribosomal protein L5 /// small nucleolar RNA, H/ACA box 66 /// small nucleolar RNA, C/D box 21 RPL5 /// SNORA66 /// SNORD21 6083 /// 6125 /// 26782 NM_000969 /// NR_000006 /// NR_002444 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210036_s_at AB044806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044806.1 /DEF=Homo sapiens HERG mRNA for HERG-USO, alternatively spliced, complete cds. /FEA=mRNA /GEN=HERG /PROD=HERG-USO /DB_XREF=gi:11933151 /UG=Hs.188021 potassium voltage-gated channel, subfamily H (eag-related), member 2 /FL=gb:AB044806.1 AB044806 potassium voltage-gated channel, subfamily H (eag-related), member 2 KCNH2 3757 NM_000238 /// NM_001204798 /// NM_172056 /// NM_172057 /// XM_006715977 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0003064 // regulation of heart rate by hormone // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0055075 // potassium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902303 // negative regulation of potassium ion export // inferred from direct assay 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 210037_s_at L24553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L24553.1 /DEF=Homo sapiens inducible nitric oxide synthase mRNA, complete cds. /FEA=mRNA /PROD=nitric oxide synthase /DB_XREF=gi:404048 /UG=Hs.193788 nitric oxide synthase 2A (inducible, hepatocytes) /FL=gb:NM_000625.1 gb:L09210.1 gb:AF068236.1 gb:L24553.1 gb:U05810.1 gb:D26525.1 gb:U20141.1 gb:U31511.1 L24553 nitric oxide synthase 2, inducible NOS2 4843 NM_000625 /// NM_153292 0001666 // response to hypoxia // inferred from electronic annotation /// 0001912 // positive regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0002227 // innate immune response in mucosa // non-traceable author statement /// 0006527 // arginine catabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0006954 // inflammatory response // not recorded /// 0007263 // nitric oxide mediated signal transduction // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0009617 // response to bacterium // non-traceable author statement /// 0010629 // negative regulation of gene expression // inferred from genetic interaction /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 0031284 // positive regulation of guanylate cyclase activity // not recorded /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043457 // regulation of cellular respiration // traceable author statement /// 0045776 // negative regulation of blood pressure // not recorded /// 0045909 // positive regulation of vasodilation // not recorded /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // non-traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0051712 // positive regulation of killing of cells of other organism // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0004517 // nitric-oxide synthase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0034617 // tetrahydrobiopterin binding // inferred from sequence or structural similarity /// 0034618 // arginine binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0050661 // NADP binding // traceable author statement 210038_at AL137145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137145 /DEF=Human DNA sequence from clone RP11-563J2 on chromosome 10 Contains ESTs, STSs, GSSs and a CpG island. Contains a novel pseudogene and the 3 part of the PRKCQ gene for protein kinase C theta /FEA=mRNA /DB_XREF=gi:9581557 /UG=Hs.211593 protein kinase C, theta /FL=gb:L07032.1 gb:NM_006257.1 gb:L01087.1 AL137145 protein kinase C, theta PRKCQ 5588 NM_001242413 /// NM_001282644 /// NM_001282645 /// NM_006257 /// XM_005252496 /// XM_005252497 /// XM_006717465 0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032740 // positive regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000570 // positive regulation of T-helper 2 cell activation // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210039_s_at L01087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L01087.1 /DEF=Human protein kinase C-theta (PRKCT) mRNA, complete cds. /FEA=mRNA /GEN=PRKCT /PROD=protein kinase C-theta /DB_XREF=gi:558098 /UG=Hs.211593 protein kinase C, theta /FL=gb:L07032.1 gb:NM_006257.1 gb:L01087.1 L01087 protein kinase C, theta PRKCQ 5588 NM_001242413 /// NM_001282644 /// NM_001282645 /// NM_006257 /// XM_005252496 /// XM_005252497 /// XM_006717465 0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032740 // positive regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000570 // positive regulation of T-helper 2 cell activation // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210040_at AF208159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF208159.1 /DEF=Homo sapiens electroneutral potassium-chloride cotransporter KCC2 (KCC2) mRNA, complete cds. /FEA=mRNA /GEN=KCC2 /PROD=electroneutral potassium-chloride cotransporterKCC2 /DB_XREF=gi:12003226 /UG=Hs.21413 solute carrier family 12, (potassium-chloride transporter) member 5 /FL=gb:NM_020708.1 gb:AF208159.1 AF208159 solute carrier family 12 (potassium/chloride transporter), member 5 SLC12A5 57468 NM_001134771 /// NM_020708 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006873 // cellular ion homeostasis // non-traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040040 // thermosensory behavior // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction 210041_s_at BC001258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001258.1 /DEF=Homo sapiens, N-acetylglucosamine-phosphate mutase, clone MGC:5002, mRNA, complete cds. /FEA=mRNA /PROD=N-acetylglucosamine-phosphate mutase /DB_XREF=gi:12654830 /UG=Hs.237323 N-acetylglucosamine-phosphate mutase /FL=gb:BC001258.1 gb:AF102265.1 gb:AF180371.1 gb:AB032081.1 BC001258 phosphoglucomutase 3 PGM3 5238 NM_001199917 /// NM_001199918 /// NM_001199919 /// NM_015599 /// XM_005248728 /// XM_006715504 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006041 // glucosamine metabolic process // non-traceable author statement /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // not recorded /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019255 // glucose 1-phosphate metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // not recorded /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004610 // phosphoacetylglucosamine mutase activity // inferred from direct assay /// 0004614 // phosphoglucomutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210042_s_at AF073890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF073890.1 /DEF=Homo sapiens cathepsin X precursor, mRNA, complete cds. /FEA=mRNA /PROD=cathepsin X precursor /DB_XREF=gi:3650497 /UG=Hs.252549 cathepsin Z /FL=gb:AF032906.1 gb:AF073890.1 gb:NM_001336.1 gb:AF136273.1 AF073890 cathepsin Z CTSZ 1522 NM_001336 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210043_at AF334946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF334946.1 /DEF=Homo sapiens FKSG44 (FKSG44) mRNA, complete cds. /FEA=mRNA /GEN=FKSG44 /PROD=FKSG44 /DB_XREF=gi:12276205 /UG=Hs.293476 Homo sapiens FKSG44 (FKSG44) mRNA, complete cds /FL=gb:AF334946.1 AF334946 FERM domain containing 8 FRMD8 83786 NM_031904 /// XM_005274349 0005856 // cytoskeleton // inferred from electronic annotation 210044_s_at BC002796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002796.1 /DEF=Homo sapiens, lymphoblastic leukemia derived sequence 1, clone MGC:3943, mRNA, complete cds. /FEA=mRNA /PROD=lymphoblastic leukemia derived sequence 1 /DB_XREF=gi:12803898 /UG=Hs.46446 lymphoblastic leukemia derived sequence 1 /FL=gb:BC002796.1 gb:NM_005583.1 BC002796 lymphoblastic leukemia associated hematopoiesis regulator 1 LYL1 4066 NM_005583 /// XM_005259912 /// XM_006722752 /// XM_006722753 /// XM_006722754 0001955 // blood vessel maturation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 210045_at AU151428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151428 /FEA=EST /DB_XREF=gi:11012949 /DB_XREF=est:AU151428 /CLONE=NT2RP2005206 /UG=Hs.5337 isocitrate dehydrogenase 2 (NADP+), mitochondrial /FL=gb:U52144.1 AU151428 isocitrate dehydrogenase 2 (NADP+), mitochondrial IDH2 3418 NM_001289910 /// NM_001290114 /// NM_002168 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006097 // glyoxylate cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004450 // isocitrate dehydrogenase (NADP+) activity // not recorded /// 0004450 // isocitrate dehydrogenase (NADP+) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210046_s_at U52144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U52144.1 /DEF=Human isocitrate dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=isocitrate dehydrogenase /DB_XREF=gi:1277202 /UG=Hs.5337 isocitrate dehydrogenase 2 (NADP+), mitochondrial /FL=gb:U52144.1 U52144 isocitrate dehydrogenase 2 (NADP+), mitochondrial IDH2 3418 NM_001289910 /// NM_001290114 /// NM_002168 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006097 // glyoxylate cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004450 // isocitrate dehydrogenase (NADP+) activity // not recorded /// 0004450 // isocitrate dehydrogenase (NADP+) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210047_at AF064484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064484.1 /DEF=Homo sapiens natural resistance-associated macrophage protein 2 non-IRE form (NRAMP2) mRNA, complete cds. /FEA=mRNA /GEN=NRAMP2 /PROD=natural resistance-associated macrophage protein2 non-IRE form /DB_XREF=gi:3211761 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:AF064484.1 AF064484 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 210048_at BC001889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001889.1 /DEF=Homo sapiens, N-ethylmaleimide-sensitive factor attachment protein, gamma, clone MGC:1699, mRNA, complete cds. /FEA=mRNA /PROD=N-ethylmaleimide-sensitive factor attachmentprotein, gamma /DB_XREF=gi:12804880 /UG=Hs.60415 N-ethylmaleimide-sensitive factor attachment protein, gamma /FL=gb:BC001889.1 gb:U78107.1 gb:NM_003826.1 BC001889 N-ethylmaleimide-sensitive factor attachment protein, gamma NAPG 8774 NM_003826 0006461 // protein complex assembly // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050821 // protein stabilization // non-traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210049_at D29832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D29832.1 /DEF=Human mRNA for antithrombin III variant, complete cds. /FEA=mRNA /PROD=antithrombin III (AT-III) variant /DB_XREF=gi:576553 /UG=Hs.75599 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 /FL=gb:AF130100.1 gb:NM_000488.1 gb:D29832.1 D29832 serpin peptidase inhibitor, clade C (antithrombin), member 1 SERPINC1 462 NM_000488 /// XM_005245198 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 2000266 // regulation of blood coagulation, intrinsic pathway // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210050_at M10036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M10036.1 /DEF=Human triosephosphate isomerase mRNA, complete cds. /FEA=mRNA /GEN=TPI1 /DB_XREF=gi:339840 /UG=Hs.83848 triosephosphate isomerase 1 /FL=gb:M10036.1 M10036 triosephosphate isomerase 1 TPI1 7167 NM_000365 /// NM_001159287 /// NM_001258026 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004807 // triose-phosphate isomerase activity // not recorded /// 0004807 // triose-phosphate isomerase activity // non-traceable author statement /// 0004807 // triose-phosphate isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 210051_at U78168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78168.1 /DEF=Homo sapiens cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI) mRNA, complete cds. /FEA=mRNA /GEN=cAMP-GEFI /PROD=cAMP-regulated guanine nucleotide exchangefactor I /DB_XREF=gi:4079648 /UG=Hs.8578 Rap1 guanine-nucleotide-exchange factor directly activated by cAMP /FL=gb:AF103905.1 gb:U78168.1 gb:NM_006105.1 U78168 Rap guanine nucleotide exchange factor (GEF) 3 RAPGEF3 10411 NM_001098531 /// NM_001098532 /// NM_006105 /// XM_005268569 /// XM_005268570 /// XM_005268571 /// XM_006719197 /// XR_429071 0001525 // angiogenesis // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030822 // positive regulation of cAMP catabolic process // non-traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from direct assay /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0030552 // cAMP binding // inferred from electronic annotation 210052_s_at AF098158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098158.1 /DEF=Homo sapiens restricted expressed proliferation associated protein 100 mRNA, complete cds. /FEA=mRNA /PROD=restricted expressed proliferation associatedprotein 100 /DB_XREF=gi:6073830 /UG=Hs.9329 chromosome 20 open reading frame 1 /FL=gb:NM_012112.1 gb:BC004136.1 gb:AB024704.1 gb:AF146731.1 gb:AF098158.1 gb:AB027467.1 AF098158 TPX2, microtubule-associated TPX2 22974 NM_012112 /// XM_005260340 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0060236 // regulation of mitotic spindle organization // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction 210053_at AW138827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138827 /FEA=EST /DB_XREF=gi:6143145 /DB_XREF=est:UI-H-BI1-aep-g-08-0-UI.s1 /CLONE=IMAGE:2720079 /UG=Hs.96103 TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD /FL=gb:U80191.1 gb:NM_006951.1 AW138827 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa TAF5 6877 NM_006951 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016568 // chromatin modification // inferred by curator /// 0016573 // histone acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 210054_at BC003648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003648.1 /DEF=Homo sapiens, clone MGC:4701, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4701) /DB_XREF=gi:13177750 /UG=Hs.116771 hypothetical protein MGC4701 /FL=gb:BC003648.1 BC003648 HAUS augmin-like complex, subunit 3 HAUS3 79441 NM_024511 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 210055_at BE045816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE045816 /FEA=EST /DB_XREF=gi:8362869 /DB_XREF=est:hq83c08.x1 /CLONE=IMAGE:3125966 /UG=Hs.123078 thyroid stimulating hormone receptor /FL=gb:M32215.1 gb:M31774.1 gb:NM_000369.1 gb:M73747.1 BE045816 thyroid stimulating hormone receptor TSHR 7253 NM_000369 /// NM_001018036 /// NM_001142626 /// XM_005268037 /// XM_005268039 /// XM_006720245 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004996 // thyroid-stimulating hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 210056_at U69563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U69563 /FEA=EST /DB_XREF=gi:2731394 /DB_XREF=est:U69563 /CLONE=25050 /UG=Hs.124940 GTP-binding protein /FL=gb:AB040147.1 gb:NM_014470.1 U69563 Rho family GTPase 1 RND1 27289 NM_014470 0006184 // GTP catabolic process // non-traceable author statement /// 0007015 // actin filament organization // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016322 // neuron remodeling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 210057_at U32581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U32581.2 /DEF=Homo sapiens lambdaiota protein kinase C-interacting protein mRNA, complete cds. /FEA=mRNA /PROD=lambdaiota protein kinase C-interactingprotein /DB_XREF=gi:5542015 /UG=Hs.168052 KIAA0421 protein /FL=gb:U32581.2 U32581 bolA family member 2 /// serine/threonine-protein kinase SMG1-like /// SMG1 phosphatidylinositol 3-kinase-related kinase BOLA2 /// LOC101060386 /// SMG1 23049 /// 552900 /// 101060386 NM_001031827 /// NM_001031833 /// NM_015092 /// XM_005255182 /// XM_005255183 /// XM_005255184 /// XM_005255185 /// XM_006726631 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210058_at BC000433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000433.1 /DEF=Homo sapiens, mitogen-activated protein kinase 13, clone MGC:8364, mRNA, complete cds. /FEA=mRNA /PROD=mitogen-activated protein kinase 13 /DB_XREF=gi:12653328 /UG=Hs.178695 mitogen-activated protein kinase 13 /FL=gb:BC000433.1 gb:BC001641.1 gb:BC004428.1 gb:AF004709.1 gb:AF015256.1 gb:U93232.1 gb:NM_002754.1 gb:AF092535.1 gb:AF100546.1 BC000433 mitogen-activated protein kinase 13 MAPK13 5603 NM_002754 /// NR_072996 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006970 // response to osmotic stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred by curator 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210059_s_at BC000433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000433.1 /DEF=Homo sapiens, mitogen-activated protein kinase 13, clone MGC:8364, mRNA, complete cds. /FEA=mRNA /PROD=mitogen-activated protein kinase 13 /DB_XREF=gi:12653328 /UG=Hs.178695 mitogen-activated protein kinase 13 /FL=gb:BC000433.1 gb:BC001641.1 gb:BC004428.1 gb:AF004709.1 gb:AF015256.1 gb:U93232.1 gb:NM_002754.1 gb:AF092535.1 gb:AF100546.1 BC000433 mitogen-activated protein kinase 13 MAPK13 5603 NM_002754 /// NR_072996 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006970 // response to osmotic stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred by curator 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210060_at M36476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36476.1 /DEF=Human cGMP phosphodiesterase gamma-subunit (PDEG) mRNA, complete cds. /FEA=mRNA /GEN=PDEG /PROD=cGMP phosphodiesterase gamma-subunit /DB_XREF=gi:189702 /UG=Hs.1857 phosphodiesterase 6G, cGMP-specific, rod, gamma /FL=gb:M36476.1 gb:NM_002602.1 M36476 phosphodiesterase 6G, cGMP-specific, rod, gamma PDE6G 5148 NM_002602 /// NR_026872 /// XM_006721942 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0097381 // photoreceptor disc membrane // traceable author statement 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 210061_at AF114817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114817.1 /DEF=Homo sapiens KRAB-zinc finger protein SZF1-2 (SZF1) mRNA, complete cds. /FEA=mRNA /GEN=SZF1 /PROD=KRAB-zinc finger protein SZF1-2 /DB_XREF=gi:5059038 /UG=Hs.19585 KRAB-zinc finger protein SZF1-1 /FL=gb:AF114817.1 AF114817 zinc finger protein 589 ZNF589 51385 NM_016089 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210062_s_at AF114817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114817.1 /DEF=Homo sapiens KRAB-zinc finger protein SZF1-2 (SZF1) mRNA, complete cds. /FEA=mRNA /GEN=SZF1 /PROD=KRAB-zinc finger protein SZF1-2 /DB_XREF=gi:5059038 /UG=Hs.19585 KRAB-zinc finger protein SZF1-1 /FL=gb:AF114817.1 AF114817 zinc finger protein 589 ZNF589 51385 NM_016089 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210063_at AF162428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF162428.1 /DEF=Homo sapiens sarcosine dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=sarcosine dehydrogenase /DB_XREF=gi:5453464 /UG=Hs.198003 sarcosine dehydrogenase /FL=gb:AF162428.1 gb:AF095735.2 AF162428 sarcosine dehydrogenase SARDH 1757 NM_001134707 /// NM_007101 /// XM_005272170 /// XM_006716990 /// XM_006716991 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008480 // sarcosine dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 210064_s_at NM_006952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006952.1 /DEF=Homo sapiens uroplakin 1B (UPK1B), mRNA. /FEA=CDS /GEN=UPK1B /PROD=uroplakin 1B /DB_XREF=gi:5902149 /UG=Hs.271580 uroplakin 1B /FL=gb:AB015234.1 gb:AF042331.1 gb:NM_006952.1 gb:AB002155.1 NM_006952 uroplakin 1B UPK1B 7348 NM_006952 0030855 // epithelial cell differentiation // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement 210065_s_at AB002155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002155.1 /DEF=Homo sapiens mRNA for human uroplakin Ib, complete cds. /FEA=mRNA /PROD=human uroplakin Ib /DB_XREF=gi:6682736 /UG=Hs.271580 uroplakin 1B /FL=gb:AB015234.1 gb:AF042331.1 gb:NM_006952.1 gb:AB002155.1 AB002155 uroplakin 1B UPK1B 7348 NM_006952 0030855 // epithelial cell differentiation // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement 210066_s_at D63412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63412.1 /DEF=Homo sapiens mRNA for aquaporin, complete cds. /FEA=mRNA /PROD=aquaporin /DB_XREF=gi:1236245 /UG=Hs.288650 aquaporin 4 /FL=gb:D63412.1 gb:U63622.1 gb:U63623.1 gb:NM_001650.2 gb:NM_004028.1 D63412 aquaporin 4 AQP4 361 NM_001650 /// NM_004028 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // not recorded /// 0015288 // porin activity // inferred from electronic annotation 210067_at D63412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63412.1 /DEF=Homo sapiens mRNA for aquaporin, complete cds. /FEA=mRNA /PROD=aquaporin /DB_XREF=gi:1236245 /UG=Hs.288650 aquaporin 4 /FL=gb:D63412.1 gb:U63622.1 gb:U63623.1 gb:NM_001650.2 gb:NM_004028.1 D63412 aquaporin 4 AQP4 361 NM_001650 /// NM_004028 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // not recorded /// 0015288 // porin activity // inferred from electronic annotation 210068_s_at U63622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63622.1 /DEF=Human aquaporin 4 (AQP4) mRNA, complete cds. /FEA=mRNA /GEN=AQP4 /PROD=aquaporin 4 /DB_XREF=gi:1680707 /UG=Hs.288650 aquaporin 4 /FL=gb:D63412.1 gb:U63622.1 gb:U63623.1 gb:NM_001650.2 gb:NM_004028.1 U63622 aquaporin 4 AQP4 361 NM_001650 /// NM_004028 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // not recorded /// 0015288 // porin activity // inferred from electronic annotation 210069_at U62733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62733.1 /DEF=Human carnitine palmitoyltransferase I mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=carnitine palmitoyltransferase I /DB_XREF=gi:1762532 /UG=Hs.29331 carnitine palmitoyltransferase I, muscle /FL=gb:D87812.1 gb:U62733.1 U62733 CHKB-CPT1B readthrough (NMD candidate) /// carnitine palmitoyltransferase 1B (muscle) CHKB-CPT1B /// CPT1B 1375 /// 386593 NM_001145134 /// NM_001145135 /// NM_001145136 /// NM_001145137 /// NM_004377 /// NM_152245 /// NM_152246 /// NM_152247 /// NR_027928 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 210070_s_at U62733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62733.1 /DEF=Human carnitine palmitoyltransferase I mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=carnitine palmitoyltransferase I /DB_XREF=gi:1762532 /UG=Hs.29331 carnitine palmitoyltransferase I, muscle /FL=gb:D87812.1 gb:U62733.1 U62733 CHKB-CPT1B readthrough (NMD candidate) /// carnitine palmitoyltransferase 1B (muscle) CHKB-CPT1B /// CPT1B 1375 /// 386593 NM_001145134 /// NM_001145135 /// NM_001145136 /// NM_001145137 /// NM_004377 /// NM_152245 /// NM_152246 /// NM_152247 /// NR_027928 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210072_at U88321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88321.1 /DEF=Human beta chemokine Exodus-3 mRNA, complete cds. /FEA=mRNA /PROD=beta chemokine Exodus-3 /DB_XREF=gi:2196921 /UG=Hs.50002 small inducible cytokine subfamily A (Cys-Cys), member 19 /FL=gb:U77180.1 gb:AB000887.1 gb:U88321.1 gb:NM_006274.1 U88321 chemokine (C-C motif) ligand 19 CCL19 6363 NM_006274 0001768 // establishment of T cell polarity // inferred from direct assay /// 0001771 // immunological synapse formation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from direct assay /// 0002408 // myeloid dendritic cell chemotaxis // inferred from direct assay /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0009615 // response to virus // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034695 // response to prostaglandin E // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045807 // positive regulation of endocytosis // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060491 // regulation of cell projection assembly // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071731 // response to nitric oxide // inferred from direct assay /// 0072610 // interleukin-12 secretion // inferred from sequence or structural similarity /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from sequence or structural similarity /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000147 // positive regulation of cell motility // inferred from direct assay /// 2000549 // positive regulation of dendritic cell dendrite assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0031732 // CCR7 chemokine receptor binding // inferred from sequence or structural similarity /// 0031735 // CCR10 chemokine receptor binding // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from direct assay /// 0048020 // CCR chemokine receptor binding // inferred from physical interaction 210073_at L32867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L32867.1 /DEF=Homo sapiens alpha 2,8-sialyltransferase mRNA, complete cds. /FEA=mRNA /PROD=alpha 2,8-sialyltransferase /DB_XREF=gi:662253 /UG=Hs.82527 sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A /FL=gb:L43494.1 gb:NM_003034.1 gb:D26360.1 gb:L32867.1 L32867 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 ST8SIA1 6489 NM_003034 /// XM_005253469 /// XM_005253470 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210074_at AF070448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070448.1 /DEF=Homo sapiens cathepsin U (CTSU) mRNA, complete cds. /FEA=mRNA /GEN=CTSU /PROD=cathepsin U /DB_XREF=gi:3228671 /UG=Hs.87417 cathepsin L2 /FL=gb:AB001928.1 gb:AF070448.1 gb:NM_001333.1 AF070448 cathepsin V CTSV 1515 NM_001201575 /// NM_001333 /// XM_006716960 0006508 // proteolysis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021675 // nerve development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060008 // Sertoli cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030984 // kininogen binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 210075_at AF151074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151074.1 /DEF=Homo sapiens HSPC240 mRNA, complete cds. /FEA=mRNA /PROD=HSPC240 /DB_XREF=gi:7106869 /UG=Hs.132744 hypothetical protein /FL=gb:AF151074.1 gb:NM_016496.1 AF151074 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase MARCH2 51257 NM_001005415 /// NM_001005416 /// NM_016496 /// XM_006722762 /// XM_006722763 0006897 // endocytosis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210076_x_at AF151813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151813.1 /DEF=Homo sapiens CGI-55 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-55 protein /DB_XREF=gi:4929578 /UG=Hs.165998 PAI-1 mRNA-binding protein /FL=gb:AF151813.1 AF151813 SERPINE1 mRNA binding protein 1 SERBP1 26135 NM_001018067 /// NM_001018068 /// NM_001018069 /// NM_015640 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210077_s_at U30884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U30884.1 /DEF=Human splicing factor SRp40-2 (SRp40) mRNA, complete cds. /FEA=mRNA /GEN=SRp40 /PROD=SRp40-2 /DB_XREF=gi:1049089 /UG=Hs.166975 splicing factor, arginineserine-rich 5 /FL=gb:U30884.1 U30884 serine/arginine-rich splicing factor 5 SRSF5 6430 NM_001039465 /// NM_006925 /// XM_005267998 /// XM_005267999 /// XM_005268000 /// XM_005268001 /// XR_429326 /// XR_429327 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 210078_s_at L39833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L39833.1 /DEF=Homo sapiens (clone hKvBeta3) K+ channel beta subunit mRNA, complete cds. /FEA=mRNA /PROD=K+ channel beta-subunit /DB_XREF=gi:666896 /UG=Hs.172471 potassium voltage-gated channel, shaker-related subfamily, beta member 1 /FL=gb:L39833.1 gb:U16953.1 L39833 potassium voltage-gated channel, shaker-related subfamily, beta member 1 KCNAB1 7881 NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 210079_x_at U16953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U16953.1 /DEF=Human potassium channel beta3 subunit mRNA, complete cds. /FEA=mRNA /PROD=potassium channel beta3 subunit /DB_XREF=gi:762887 /UG=Hs.172471 potassium voltage-gated channel, shaker-related subfamily, beta member 1 /FL=gb:L39833.1 gb:U16953.1 U16953 potassium voltage-gated channel, shaker-related subfamily, beta member 1 KCNAB1 7881 NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 210080_x_at D00306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D00306.1 /DEF=Homo sapiens mRNA for pancreatic protease E precursor, complete cds. /FEA=mRNA /PROD=pancreatic protease E precursor /DB_XREF=gi:220013 /UG=Hs.181289 elastase 3, pancreatic (protease E) /FL=gb:D00306.1 gb:NM_005747.1 D00306 chymotrypsin-like elastase family, member 3A CELA3A 10136 NM_005747 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210081_at AB036432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB036432.1 /DEF=Homo sapiens RAGE mRNA for advanced glycation endproducts receptor, complete cds. /FEA=mRNA /GEN=RAGE /PROD=advanced glycation endproducts receptor /DB_XREF=gi:6691625 /UG=Hs.184 advanced glycosylation end product-specific receptor /FL=gb:NM_001136.1 gb:AB036432.1 AB036432 advanced glycosylation end product-specific receptor AGER 177 NM_001136 /// NM_001206929 /// NM_001206932 /// NM_001206934 /// NM_001206936 /// NM_001206940 /// NM_001206954 /// NM_001206966 /// NM_172197 /// NR_038190 0006954 // inflammatory response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0031175 // neuron projection development // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction 210082_at U88667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88667.1 /DEF=Human ATP binding cassette transporter (ABCR) mRNA, complete cds. /FEA=mRNA /GEN=ABCR /PROD=ATP-binding cassette transporter /DB_XREF=gi:1888526 /UG=Hs.198396 ATP-binding cassette, sub-family A (ABC1), member 4 /FL=gb:U88667.1 gb:AF001945.1 gb:AF000148.1 gb:NM_000350.1 U88667 ATP-binding cassette, sub-family A (ABC1), member 4 ABCA4 24 NM_000350 0001523 // retinoid metabolic process // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006649 // phospholipid transfer to membrane // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005548 // phospholipid transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 210083_at AF071542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF071542.1 /DEF=Homo sapiens semaphorin K1 mRNA, complete cds. /FEA=mRNA /PROD=semaphorin K1 /DB_XREF=gi:3930578 /UG=Hs.24640 sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A /FL=gb:AF030698.1 gb:AF071542.1 gb:AF069493.1 gb:NM_003612.1 AF071542 semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) SEMA7A 8482 NM_001146029 /// NM_001146030 /// NM_003612 /// XM_005254721 0001649 // osteoblast differentiation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210084_x_at AF206665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF206665.1 /DEF=Homo sapiens mast cell alpha II tryptase mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=mast cell alpha II tryptase /DB_XREF=gi:11493897 /UG=Hs.250700 tryptase beta 1 /FL=gb:AF206665.1 AF206665 tryptase alpha/beta 1 TPSAB1 7177 NM_003294 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 210085_s_at AF230929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230929.1 /DEF=Homo sapiens keratinocyte annexin-like protein pemphaxin mRNA, complete cds. /FEA=mRNA /PROD=keratinocyte annexin-like protein pemphaxin /DB_XREF=gi:10436073 /UG=Hs.279928 annexin A9 /FL=gb:AF230929.1 gb:NM_003568.1 AF230929 annexin A9 ANXA9 8416 NM_003568 /// XM_005245539 0007268 // synaptic transmission // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement 210086_at AF039196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF039196.2 /DEF=Homo sapiens putative single zinc finger transcription factor protein (hairless) mRNA, complete cds. /FEA=mRNA /GEN=hairless /PROD=putative single zinc finger transcription factorprotein /DB_XREF=gi:5042382 /UG=Hs.284126 hairless (mouse) homolog /FL=gb:AF039196.2 AF039196 hair growth associated HR 55806 NM_005144 /// NM_018411 /// XM_005273569 /// XM_006716367 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0016604 // nuclear body // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210087_s_at AF095727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF095727.1 /DEF=Homo sapiens myelin protein zero-like protein MPZL1a mRNA, complete cds. /FEA=mRNA /PROD=myelin protein zero-like protein MPZL1a /DB_XREF=gi:6002658 /UG=Hs.287832 myelin protein zero-like 1 /FL=gb:AF087020.1 gb:NM_003953.1 gb:AF092425.1 gb:AF095726.1 gb:AF095727.1 AF095727 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210088_x_at M36172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36172.1 /DEF=Human embryonic myosin alkali light chain (MLC1) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:188580 /UG=Hs.298161 myosin, light polypeptide 4, alkali; atrial, embryonic /FL=gb:M36172.1 gb:M24121.1 gb:NM_002476.1 M36172 myosin, light chain 4, alkali; atrial, embryonic MYL4 4635 NM_001002841 /// NM_002476 /// XM_005257391 /// XM_005257392 0002026 // regulation of the force of heart contraction // inferred from mutant phenotype /// 0007517 // muscle organ development // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0031672 // A band // inferred from mutant phenotype 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0032038 // myosin II heavy chain binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from mutant phenotype 210089_s_at BC004241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004241.1 /DEF=Homo sapiens, Similar to laminin, alpha 4, clone MGC:10389, mRNA, complete cds. /FEA=mRNA /PROD=Similar to laminin, alpha 4 /DB_XREF=gi:13278992 /UG=Hs.327703 Homo sapiens, Similar to laminin, alpha 4, clone MGC:10389, mRNA, complete cds /FL=gb:BC004241.1 BC004241 laminin, alpha 4 LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210090_at AF193421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF193421.1 /DEF=Homo sapiens ARC mRNA, complete cds. /FEA=mRNA /GEN=ARC /PROD=ARC /DB_XREF=gi:6319151 /UG=Hs.40888 activity-regulated cytoskeleton-associated protein /FL=gb:AF193421.1 gb:NM_015193.1 AF193421 activity-regulated cytoskeleton-associated protein ARC 23237 NM_015193 0006897 // endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210091_s_at U46745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46745.1 /DEF=Human dystrobrevin-beta mRNA, complete cds. /FEA=mRNA /PROD=dystrobrevin-beta /DB_XREF=gi:1256012 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:U46745.1 gb:NM_001391.1 U46745 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210092_at AF067173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067173.1 /DEF=Homo sapiens Mago homolog mRNA, complete cds. /FEA=mRNA /PROD=Mago homolog /DB_XREF=gi:4894379 /UG=Hs.57904 mago-nashi (Drosophila) homolog, proliferation-associated /FL=gb:AF035940.1 gb:AF067173.1 gb:NM_002370.2 AF067173 mago-nashi homolog, proliferation-associated (Drosophila) /// mago-nashi homolog B (Drosophila) MAGOH /// MAGOHB 4116 /// 55110 NM_002370 /// NM_018048 /// XM_005253402 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210093_s_at AF067173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067173.1 /DEF=Homo sapiens Mago homolog mRNA, complete cds. /FEA=mRNA /PROD=Mago homolog /DB_XREF=gi:4894379 /UG=Hs.57904 mago-nashi (Drosophila) homolog, proliferation-associated /FL=gb:AF035940.1 gb:AF067173.1 gb:NM_002370.2 AF067173 mago-nashi homolog, proliferation-associated (Drosophila) /// mago-nashi homolog B (Drosophila) MAGOH /// MAGOHB 4116 /// 55110 NM_002370 /// NM_018048 /// XM_005253402 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210094_s_at AF196186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF196186.1 /DEF=Homo sapiens atypical PKC isotype-specific interacting protein short variant mRNA, complete cds. /FEA=mRNA /PROD=atypical PKC isotype-specific interactingprotein short variant /DB_XREF=gi:13491611 /UG=Hs.72249 three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect) /FL=gb:AF196186.1 AF196186 par-3 family cell polarity regulator PARD3 56288 NM_001184785 /// NM_001184786 /// NM_001184787 /// NM_001184788 /// NM_001184789 /// NM_001184790 /// NM_001184791 /// NM_001184792 /// NM_001184793 /// NM_001184794 /// NM_019619 /// XM_005252528 /// XM_005252530 /// XM_005252531 /// XM_005252532 /// XM_005252534 /// XM_005252535 /// XM_005252536 /// XM_006717471 /// XM_006717472 /// XM_006717473 /// XM_006717474 /// XM_006717475 /// XM_006717476 /// XM_006717477 /// XM_006717478 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0003383 // apical constriction // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008356 // asymmetric cell division // traceable author statement /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0044319 // wound healing, spreading of cells // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060341 // regulation of cellular localization // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0033269 // internode region of axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from sequence or structural similarity 210095_s_at M31159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31159.1 /DEF=Human growth hormone-dependent insulin-like growth factor-binding protein mRNA, complete cds. /FEA=mRNA /GEN=IGFBP1 /DB_XREF=gi:183115 /UG=Hs.77326 insulin-like growth factor binding protein 3 /FL=gb:BC000013.1 gb:M31159.1 M31159 insulin-like growth factor binding protein 3 IGFBP3 3486 NM_000598 /// NM_001013398 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from genetic interaction /// 0009968 // negative regulation of signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008160 // protein tyrosine phosphatase activator activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0046872 // metal ion binding // non-traceable author statement 210096_at J02871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J02871.1 /DEF=Human lung cytochrome P450 (IV subfamily) BI protein, complete cds. /FEA=mRNA /DB_XREF=gi:180968 /UG=Hs.687 cytochrome P450, subfamily IVB, polypeptide 1 /FL=gb:NM_000779.2 gb:J02871.1 J02871 cytochrome P450, family 4, subfamily B, polypeptide 1 CYP4B1 1580 NM_000779 /// NM_001099772 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0018879 // biphenyl metabolic process // inferred from electronic annotation /// 0018917 // fluorene metabolic process // inferred from electronic annotation /// 0042738 // exogenous drug catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018585 // fluorene oxygenase activity // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 210097_s_at AF130102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF130102.1 /DEF=Homo sapiens clone FLB2205 PRO0522 mRNA, complete cds. /FEA=mRNA /PROD=PRO0522 /DB_XREF=gi:11493507 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF130102.1 AF130102 nucleolar protein 7, 27kDa NOL7 51406 NM_016167 /// XM_005249173 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 210098_s_at AF130102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130102.1 /DEF=Homo sapiens clone FLB2205 PRO0522 mRNA, complete cds. /FEA=mRNA /PROD=PRO0522 /DB_XREF=gi:11493507 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF130102.1 AF130102 210099_at AF327657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF327657.1 /DEF=Homo sapiens ABC transporter ABCA2 (ABCA2) mRNA, complete cds. /FEA=mRNA /GEN=ABCA2 /PROD=ABC transporter ABCA2 /DB_XREF=gi:13173185 /UG=Hs.121561 ATP-binding cassette, sub-family A (ABC1), member 2 /FL=gb:AF327657.1 gb:AF178941.1 AF327657 ATP-binding cassette, sub-family A (ABC1), member 2 ABCA2 20 NM_001606 /// NM_212533 /// XM_006716996 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032383 // regulation of intracellular cholesterol transport // inferred from mutant phenotype /// 0042493 // response to drug // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from expression pattern /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0055085 // transmembrane transport // non-traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from reviewed computational analysis /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from reviewed computational analysis /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement 0000166 // nucleotide binding // inferred from reviewed computational analysis /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement 210100_s_at AF327657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF327657.1 /DEF=Homo sapiens ABC transporter ABCA2 (ABCA2) mRNA, complete cds. /FEA=mRNA /GEN=ABCA2 /PROD=ABC transporter ABCA2 /DB_XREF=gi:13173185 /UG=Hs.121561 ATP-binding cassette, sub-family A (ABC1), member 2 /FL=gb:AF327657.1 gb:AF178941.1 AF327657 ATP-binding cassette, sub-family A (ABC1), member 2 ABCA2 20 NM_001606 /// NM_212533 /// XM_006716996 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032383 // regulation of intracellular cholesterol transport // inferred from mutant phenotype /// 0042493 // response to drug // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from expression pattern /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0055085 // transmembrane transport // non-traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from reviewed computational analysis /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from reviewed computational analysis /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement 0000166 // nucleotide binding // inferred from reviewed computational analysis /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement 210101_x_at AF257318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF257318.1 /DEF=Homo sapiens SH3-containing protein SH3GLB1 mRNA, complete cds. /FEA=mRNA /PROD=SH3-containing protein SH3GLB1 /DB_XREF=gi:8896091 /UG=Hs.136309 SH3-containing protein SH3GLB1 /FL=gb:AF350371.1 gb:AF151819.1 gb:NM_016009.1 gb:AF257318.1 AF257318 SH3-domain GRB2-like endophilin B1 SH3GLB1 51100 NM_001206651 /// NM_001206652 /// NM_001206653 /// NM_016009 /// XM_006710672 /// XM_006710673 0006654 // phosphatidic acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005504 // fatty acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 210102_at BC001234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001234.1 /DEF=Homo sapiens, Similar to loss of heterozygosity, 11, chromosomal region 2, gene A, clone MGC:4904, mRNA, complete cds. /FEA=mRNA /PROD=Similar to loss of heterozygosity, 11,chromosomal region 2, gene A /DB_XREF=gi:12654782 /UG=Hs.152944 loss of heterozygosity, 11, chromosomal region 2, gene A /FL=gb:BC001234.1 BC001234 von Willebrand factor A domain containing 5A VWA5A 4013 NM_001130142 /// NM_014622 /// NM_198315 0005634 // nucleus // inferred from direct assay 210103_s_at AB028021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB028021.1 /DEF=Homo sapiens HNF-3beta mRNA for hepatocyte nuclear factor-3 beta, complete cds. /FEA=mRNA /GEN=HNF-3beta /PROD=hepatocyte nuclear factor-3 beta /DB_XREF=gi:4958949 /UG=Hs.155651 hepatocyte nuclear factor 3, beta /FL=gb:NM_021784.1 gb:AB028021.1 AB028021 forkhead box A2 FOXA2 3170 NM_021784 /// NM_153675 /// XM_006723562 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0000433 // negative regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // not recorded /// 0001705 // ectoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010817 // regulation of hormone levels // not recorded /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from direct assay /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from sequence or structural similarity /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // not recorded /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // not recorded /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048665 // neuron fate specification // not recorded /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061448 // connective tissue development // inferred from electronic annotation /// 0070741 // response to interleukin-6 // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from sequence or structural similarity /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred by curator /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2000971 // negative regulation of detection of glucose // inferred from sequence or structural similarity /// 2000976 // regulation of transcription from RNA polymerase II promoter involved in detection of glucose // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 210104_at AF074723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074723.1 /DEF=Homo sapiens RNA polymerase transcriptional regulation mediator (MED6) mRNA, complete cds. /FEA=mRNA /GEN=MED6 /PROD=RNA polymerase transcriptional regulationmediator /DB_XREF=gi:3329505 /UG=Hs.167738 RNA polymerase II transcriptional regulation mediator (Med6, S. cerevisiae, homolog of) /FL=gb:BC004106.1 gb:AF074723.1 AF074723 mediator complex subunit 6 MED6 10001 NM_001284209 /// NM_001284210 /// NM_001284211 /// NM_005466 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction 210105_s_at M14333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M14333.1 /DEF=Homo sapiens c-syn protooncogene mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181171 /UG=Hs.169370 FYN oncogene related to SRC, FGR, YES /FL=gb:M14333.1 gb:M14676.1 gb:NM_002037.1 M14333 FYN proto-oncogene, Src family tyrosine kinase FYN 2534 NM_001242779 /// NM_002037 /// NM_153047 /// NM_153048 /// XM_005266887 /// XM_005266888 /// XM_005266889 /// XM_005266890 /// XM_005266892 /// XM_006715429 0001764 // neuron migration // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007612 // learning // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 1900182 // positive regulation of protein localization to nucleus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042609 // CD4 receptor binding // inferred from electronic annotation /// 0042610 // CD8 receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation /// 0070851 // growth factor receptor binding // inferred from physical interaction 210106_at U43559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43559.1 /DEF=Human 11-cis retinol dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=11-cis retinol dehydrogenase /DB_XREF=gi:1616653 /UG=Hs.172914 retinol dehydrogenase 5 (11-cisand 9-cis) /FL=gb:U43559.1 gb:U89717.1 gb:NM_002905.1 U43559 BLOC1S1-RDH5 readthrough /// retinol dehydrogenase 5 (11-cis/9-cis) BLOC1S1-RDH5 /// RDH5 5959 /// 100528022 NM_001199771 /// NM_002905 /// NR_037658 0001523 // retinoid metabolic process // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0004745 // retinol dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 210107_at AF127036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF127036.1 /DEF=Homo sapiens calcium-activated chloride channel protein 1 (CaCC1) mRNA, complete cds. /FEA=mRNA /GEN=CaCC1 /PROD=calcium-activated chloride channel protein 1 /DB_XREF=gi:4585468 /UG=Hs.194659 chloride channel, calcium activated, family member 1 /FL=gb:AF039400.1 gb:NM_001285.1 gb:AF127036.1 AF127036 chloride channel accessory 1 CLCA1 1179 NM_001285 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210108_at BE550599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE550599 /FEA=EST /DB_XREF=gi:9792291 /DB_XREF=est:7a30a06.x1 /CLONE=IMAGE:3220210 /UG=Hs.23838 calcium channel, voltage-dependent, L type, alpha 1D subunit /FL=gb:M76558.1 BE550599 calcium channel, voltage-dependent, L type, alpha 1D subunit CACNA1D 776 NM_000720 /// NM_001128839 /// NM_001128840 /// XM_005265448 /// XM_006713325 0006066 // alcohol metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019285 // glycine betaine biosynthetic process from choline // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0086010 // membrane depolarization during action potential // not recorded /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred by curator /// 0086046 // membrane depolarization during SA node cell action potential // inferred from electronic annotation /// 0086052 // membrane repolarization during SA node cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901379 // regulation of potassium ion transmembrane transport // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay /// 0008812 // choline dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from physical interaction /// 0086007 // voltage-gated calcium channel activity involved in cardiac muscle cell action potential // inferred by curator /// 0086059 // voltage-gated calcium channel activity involved SA node cell action potential // inferred from mutant phenotype 210109_at AF191492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF191492.1 /DEF=Homo sapiens nasopharyngeal carcinoma associated gene protein-8 (NAG8) mRNA, complete cds. /FEA=mRNA /GEN=NAG8 /PROD=nasopharyngeal carcinoma associated geneprotein-8 /DB_XREF=gi:11065903 /UG=Hs.26937 brain and nasopharyngeal carcinoma susceptibility protein /FL=gb:AF191492.1 AF191492 SND1 intronic transcript 1 (non-protein coding) SND1-IT1 27099 NM_014411 /// NR_027330 210110_x_at AF132363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF132363.1 /DEF=Homo sapiens hnRNP 2H9D mRNA, complete cds. /FEA=mRNA /PROD=hnRNP 2H9D /DB_XREF=gi:7739446 /UG=Hs.279681 heterogeneous nuclear ribonucleoprotein H3 (2H9) /FL=gb:AF132363.1 AF132363 heterogeneous nuclear ribonucleoprotein H3 (2H9) HNRNPH3 3189 NM_012207 /// NM_021644 /// XM_005269748 /// XM_005269749 /// XM_005269751 /// XM_005269752 /// XM_005269753 /// XM_005269754 /// XM_006717816 /// XM_006717817 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210111_s_at AF277175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF277175.1 /DEF=Homo sapiens PNAS-138 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-138 /DB_XREF=gi:12751080 /UG=Hs.326790 Homo sapiens PNAS-138 mRNA, complete cds /FL=gb:AF277175.1 AF277175 kelch domain containing 10 KLHDC10 23008 NM_014997 /// XM_005250233 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210112_at U96721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96721.1 /DEF=Homo sapiens alternative Hermansky-Pudlak syndrome associated protein (HPS) mRNA, complete cds. /FEA=mRNA /GEN=HPS /PROD=alternative Hermansky-Pudlak syndrome associatedprotein /DB_XREF=gi:2454272 /UG=Hs.83951 Hermansky-Pudlak syndrome /FL=gb:BC000175.2 gb:U96721.1 U96721 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 210113_s_at AF310105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF310105.1 /DEF=Homo sapiens NALP1 mRNA, complete cds. /FEA=mRNA /PROD=NALP1 /DB_XREF=gi:11096302 /UG=Hs.104305 death effector filament-forming Ced-4-like apoptosis protein /FL=gb:AF310105.1 gb:AF229059.1 gb:AB023143.1 gb:NM_014922.1 AF310105 NLR family, pyrin domain containing 1 NLRP1 22861 NM_001033053 /// NM_014922 /// NM_033004 /// NM_033006 /// NM_033007 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051402 // neuron apoptotic process // inferred from direct assay 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072558 // NLRP1 inflammasome complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 210114_at AF039217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF039217.1 /DEF=Homo sapiens inv candidate homolog mRNA, complete cds. /FEA=mRNA /PROD=inv candidate homolog /DB_XREF=gi:4104744 /UG=Hs.104715 inversin /FL=gb:AF084367.1 gb:AF039217.1 gb:NM_014425.1 AF039217 inversin INVS 27130 NM_014425 /// NM_183245 /// NR_051962 /// XM_005251923 /// XM_005251924 /// XR_242585 /// XR_242586 /// XR_428522 0001822 // kidney development // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0060971 // embryonic heart tube left/right pattern formation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 210115_at L05096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L05096.1 /DEF=Homo sapiens ribosomal protein L39 mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L39 /DB_XREF=gi:388035 /UG=Hs.132748 Homo sapiens ribosomal protein L39 mRNA, complete cds /FL=gb:L05096.1 L05096 ribosomal protein L39-like RPL39L 116832 NM_052969 0006412 // translation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 210116_at AF072930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF072930.1 /DEF=Homo sapiens clone 14 T cell signal transduction molecule SAP mRNA, complete cds. /FEA=mRNA /PROD=T cell signal transduction molecule SAP /DB_XREF=gi:3695068 /UG=Hs.151544 SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome) /FL=gb:AF072930.1 gb:AF073019.1 gb:AF100541.1 gb:NM_002351.1 AF072930 SH2 domain containing 1A SH2D1A 4068 NM_001114937 /// NM_002351 0006959 // humoral immune response // inferred from electronic annotation /// 0006968 // cellular defense response // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210117_at AF311312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF311312.1 /DEF=Homo sapiens infertility-related sperm protein mRNA, complete cds. /FEA=mRNA /PROD=infertility-related sperm protein /DB_XREF=gi:10863767 /UG=Hs.153057 sperm associated antigen 1 /FL=gb:AF311312.1 gb:NM_003114.1 AF311312 sperm associated antigen 1 SPAG1 6674 NM_003114 /// NM_172218 /// XM_006716619 /// XM_006716620 0007338 // single fertilization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0070286 // axonemal dynein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210118_s_at M15329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15329.1 /DEF=Human interleukin 1-alpha (IL1A) mRNA, complete cds. /FEA=mRNA /GEN=IL1A /PROD=interleukin 1-alpha /DB_XREF=gi:186277 /UG=Hs.1722 interleukin 1, alpha /FL=gb:M15329.1 M15329 interleukin 1, alpha IL1A 3552 NM_000575 0001660 // fever generation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0005125 // cytokine activity // inferred from mutant phenotype /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 210119_at U73191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73191.1 /DEF=Human inward rectifier potassium channel (Kir1.3), complete cds. /FEA=mRNA /GEN=Kir1.3 /PROD=inward rectifier potassium channel /DB_XREF=gi:1765984 /UG=Hs.17287 potassium inwardly-rectifying channel, subfamily J, member 15 /FL=gb:U73191.1 gb:NM_002243.1 U73191 potassium inwardly-rectifying channel, subfamily J, member 15 KCNJ15 3772 NM_001276435 /// NM_001276436 /// NM_001276437 /// NM_001276438 /// NM_001276439 /// NM_002243 /// NM_170736 /// NM_170737 /// XM_005260975 /// XM_005260976 /// XM_006724002 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210120_s_at BC004349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004349.1 /DEF=Homo sapiens, Similar to RAN binding protein 3, clone MGC:1177, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RAN binding protein 3 /DB_XREF=gi:13279301 /UG=Hs.176657 RAN binding protein 3 /FL=gb:BC004349.1 BC004349 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 210121_at AF288390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288390.1 /DEF=Homo sapiens B3GALT2 mRNA, complete cds. /FEA=mRNA /PROD=B3GALT2 /DB_XREF=gi:12620189 /UG=Hs.181353 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 /FL=gb:AF288390.1 gb:NM_003783.1 AF288390 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 B3GALT2 8707 NM_003783 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210122_at BC005303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005303.1 /DEF=Homo sapiens, Similar to protamine 2, clone MGC:12373, mRNA, complete cds. /FEA=mRNA /PROD=Similar to protamine 2 /DB_XREF=gi:13529034 /UG=Hs.2324 protamine 2 /FL=gb:BC005303.1 gb:NM_002762.1 BC005303 protamine 2 PRM2 5620 NM_001286356 /// NM_001286357 /// NM_001286358 /// NM_001286359 /// NM_002762 /// NR_104428 0006323 // DNA packaging // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 210123_s_at U62436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62436.1 /DEF=Human nicotinic acetylcholine receptor alpha7 subunit precursor, mRNA, complete cds. /FEA=mRNA /PROD=nicotinic acetylcholine receptor alpha7 subunitprecursor /DB_XREF=gi:1458119 /UG=Hs.2540 cholinergic receptor, nicotinic, alpha polypeptide 7 /FL=gb:U40583.1 gb:U62436.1 gb:NM_000746.1 U62436 CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion /// cholinergic receptor, nicotinic, alpha 7 (neuronal) /// CHRNA7-FAM7A fusion protein-like /// uncharacterized LOC101930361 CHRFAM7A /// CHRNA7 /// LOC101929970 /// LOC101930361 1139 /// 89832 /// 101929970 /// 101930361 NM_000746 /// NM_001190455 /// NM_139320 /// NM_148911 /// NR_046324 /// XM_005254750 /// XM_005276472 /// XM_006725563 /// XR_250614 0000187 // activation of MAPK activity // inferred from direct assay /// 0001666 // response to hypoxia // inferred from direct assay /// 0001988 // positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from electronic annotation /// 0007613 // memory // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008306 // associative learning // inferred from electronic annotation /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032225 // regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034766 // negative regulation of ion transmembrane transport // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0050890 // cognition // non-traceable author statement /// 0060112 // generation of ovulation cycle rhythm // inferred from electronic annotation /// 1903049 // negative regulation of acetylcholine-gated cation channel activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032279 // asymmetric synapse // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0015643 // toxic substance binding // inferred from direct assay /// 0017081 // chloride channel regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0022848 // acetylcholine-gated cation channel activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 210124_x_at AL136552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136552.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761O15121 (from clone DKFZp761O15121); complete cds. /FEA=mRNA /GEN=DKFZp761O15121 /PROD=hypothetical protein /DB_XREF=gi:13276610 /UG=Hs.25887 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F /FL=gb:AL136552.1 AL136552 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F SEMA4F 10505 NM_001271661 /// NM_001271662 /// NM_004263 /// NR_073398 /// NR_073399 /// XM_006711919 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210125_s_at AF044773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF044773.1 /DEF=Homo sapiens breakpoint cluster region protein 1 (BCRG1) mRNA, complete cds. /FEA=mRNA /GEN=BCRG1 /PROD=breakpoint cluster region protein 1 /DB_XREF=gi:3002950 /UG=Hs.268763 Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor /FL=gb:AF044773.1 AF044773 barrier to autointegration factor 1 BANF1 8815 NM_001143985 /// NM_003860 0000278 // mitotic cell cycle // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210126_at M94890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M94890.1 /DEF=Human pregnancy-specific beta-1-glycoprotein 11 (PSG11) mRNA, complete cds. /FEA=mRNA /GEN=PSG11 /PROD=pregnancy-specific beta-1 glycoprotein /DB_XREF=gi:190567 /UG=Hs.272620 pregnancy specific beta-1-glycoprotein 9 /FL=gb:M94890.1 M94890 pregnancy specific beta-1-glycoprotein 9 PSG9 5678 NM_002784 /// XM_005259074 /// XM_005259075 /// XM_005259076 /// XM_005259077 /// XM_005259078 /// XM_005259079 0006952 // defense response // non-traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 210127_at BC002510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002510.1 /DEF=Homo sapiens, small GTPase RAB6B, clone MGC:829, mRNA, complete cds. /FEA=mRNA /PROD=small GTPase RAB6B /DB_XREF=gi:12803378 /UG=Hs.277445 RAB6B, member RAS oncogene family /FL=gb:BC002510.1 gb:AF166492.1 gb:NM_016577.1 BC002510 RAB6B, member RAS oncogene family RAB6B 51560 NM_016577 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 210128_s_at U41070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U41070.1 /DEF=Human P2 purinergic receptor mRNA, complete cds. /FEA=mRNA /PROD=P2 purinergic receptor /DB_XREF=gi:1469913 /UG=Hs.28408 leukotriene b4 receptor (chemokine receptor-like 1) /FL=gb:U41070.1 gb:D89079.1 U41070 leukotriene B4 receptor LTB4R 1241 NM_001143919 /// NM_181657 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // traceable author statement /// 0001632 // leukotriene B4 receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // traceable author statement 210129_s_at AF078842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078842.1 /DEF=Homo sapiens HOTTL protein mRNA, complete cds. /FEA=mRNA /PROD=HOTTL protein /DB_XREF=gi:6683744 /UG=Hs.289010 DKFZP434B103 protein /FL=gb:AF078842.1 AF078842 actin related protein 2/3 complex, subunit 4, 20kDa /// ARPC4-TTLL3 readthrough /// tubulin tyrosine ligase-like family, member 3 ARPC4 /// ARPC4-TTLL3 /// TTLL3 10093 /// 26140 /// 100526693 NM_001024959 /// NM_001024960 /// NM_001025930 /// NM_001198780 /// NM_001198793 /// NM_005718 /// NM_015644 /// NR_037162 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0018094 // protein polyglycylation // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0035082 // axoneme assembly // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement /// 0070735 // protein-glycine ligase activity // inferred from direct assay /// 0070736 // protein-glycine ligase activity, initiating // inferred from sequence or structural similarity 210130_s_at AF096304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF096304.1 /DEF=Homo sapiens putative sterol reductase SR-1 (TM7SF2) mRNA, complete cds. /FEA=mRNA /GEN=TM7SF2 /PROD=putative sterol reductase SR-1 /DB_XREF=gi:4191395 /UG=Hs.31130 transmembrane 7 superfamily member 2 /FL=gb:AF096304.1 AF096304 transmembrane 7 superfamily member 2 TM7SF2 7108 NM_001277233 /// NM_003273 /// NR_102367 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050613 // delta14-sterol reductase activity // inferred from electronic annotation 210131_x_at D49737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D49737.1 /DEF=Homo sapiens mRNA for cytochrome b large subunit of complex II, complete cds. /FEA=mRNA /PROD=cytochrome b large subunit of complex II /DB_XREF=gi:2588778 /UG=Hs.3577 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD /FL=gb:D49737.1 D49737 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa SDHC 6391 NM_001035511 /// NM_001035512 /// NM_001035513 /// NM_001278172 /// NM_003001 /// NR_103459 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0045273 // respiratory chain complex II // traceable author statement /// 0045281 // succinate dehydrogenase complex // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 210132_at AW189015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW189015 /FEA=EST /DB_XREF=gi:6463451 /DB_XREF=est:xk98d10.x1 /CLONE=IMAGE:2674771 /UG=Hs.37054 ephrin-A3 /FL=gb:NM_004952.1 gb:L37360.1 gb:U14187.1 AW189015 ephrin-A3 EFNA3 1944 NM_004952 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // not recorded /// 0048013 // ephrin receptor signaling pathway // not recorded /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0046875 // ephrin receptor binding // inferred from physical interaction 210133_at D49372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D49372.1 /DEF=Human mRNA for eotaxin, complete cds. /FEA=mRNA /PROD=eotaxin /DB_XREF=gi:1552240 /UG=Hs.54460 small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) /FL=gb:U46573.1 gb:D49372.1 gb:NM_002986.1 D49372 chemokine (C-C motif) ligand 11 CCL11 6356 NM_002986 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009314 // response to radiation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070670 // response to interleukin-4 // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay 210134_x_at AI816713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI816713 /FEA=EST /DB_XREF=gi:5435792 /DB_XREF=est:wj43b06.x1 /CLONE=IMAGE:2405555 /UG=Hs.55967 short stature homeobox 2 /FL=gb:AF022654.1 AI816713 short stature homeobox 2 SHOX2 6474 NM_001163678 /// NM_003030 /// NM_006884 /// XM_006713727 /// XM_006713728 /// XM_006713729 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003170 // heart valve development // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210135_s_at AF022654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022654.1 /DEF=Homo sapiens homeodomain protein (OG12) mRNA, complete cds. /FEA=mRNA /GEN=OG12 /PROD=homeodomain protein /DB_XREF=gi:2979679 /UG=Hs.55967 short stature homeobox 2 /FL=gb:AF022654.1 AF022654 short stature homeobox 2 SHOX2 6474 NM_001163678 /// NM_003030 /// NM_006884 /// XM_006713727 /// XM_006713728 /// XM_006713729 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003170 // heart valve development // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210136_at AW070431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW070431 /FEA=EST /DB_XREF=gi:6025429 /DB_XREF=est:xa11b04.x1 /CLONE=IMAGE:2567983 /UG=Hs.69547 myelin basic protein /FL=gb:L18865.1 AW070431 myelin basic protein MBP 4155 NM_001025081 /// NM_001025090 /// NM_001025092 /// NM_001025094 /// NM_001025098 /// NM_001025100 /// NM_001025101 /// NM_002385 /// XM_005266699 /// XR_245459 /// XR_245460 /// XR_245461 /// XR_430073 /// XR_430074 0006955 // immune response // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008366 // axon ensheathment // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042552 // myelination // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0061024 // membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033269 // internode region of axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 210137_s_at BC001286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001286.1 /DEF=Homo sapiens, Similar to dCMP deaminase, clone MGC:5160, mRNA, complete cds. /FEA=mRNA /PROD=Similar to dCMP deaminase /DB_XREF=gi:12654884 /UG=Hs.76894 dCMP deaminase /FL=gb:BC001286.1 BC001286 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 /// XM_005262778 /// XM_005262779 /// XM_005262780 /// XM_005262781 /// XM_005262782 /// XM_006714113 /// XM_006714114 /// XM_006714115 /// XM_006714116 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210138_at AF074979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074979.1 /DEF=Homo sapiens regulator of G protein signaling-Z (RGSZ1) mRNA, complete cds. /FEA=mRNA /GEN=RGSZ1 /PROD=regulator of G protein signaling /DB_XREF=gi:3523159 /UG=Hs.99236 regulator of G-protein signalling 20 /FL=gb:AF060877.2 gb:NM_003702.2 gb:AF074979.1 AF074979 regulator of G-protein signaling 20 RGS20 8601 NM_001286673 /// NM_001286674 /// NM_001286675 /// NM_003702 /// NM_170587 /// NR_104578 /// NR_104579 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 210139_s_at L03203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L03203.1 /DEF=Human peripheral myelin protein 22 (GAS3) mRNA, complete cds. /FEA=mRNA /GEN=GAS3 /PROD=peripheral myelin protein 22 /DB_XREF=gi:182984 /UG=Hs.103724 peripheral myelin protein 22 /FL=gb:L03203.1 L03203 peripheral myelin protein 22 PMP22 5376 NM_000304 /// NM_001281455 /// NM_001281456 /// NM_153321 /// NM_153322 /// NR_104017 /// NR_104018 0007268 // synaptic transmission // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210140_at AF031824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031824.1 /DEF=Homo sapiens leukocystatin mRNA, complete cds. /FEA=mRNA /PROD=leukocystatin /DB_XREF=gi:3252857 /UG=Hs.143212 cystatin F (leukocystatin) /FL=gb:AF031824.1 gb:AF036342.1 gb:AB015225.1 gb:NM_003650.1 AF031824 cystatin F (leukocystatin) CST7 8530 NM_003650 0006955 // immune response // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210141_s_at M13981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13981.1 /DEF=Human inhibin A-subunit mRNA, complete cds. /FEA=mRNA /GEN=INHA /DB_XREF=gi:186410 /UG=Hs.1734 inhibin, alpha /FL=gb:M13981.1 gb:NM_002191.2 M13981 inhibin, alpha INHA 3623 NM_002191 0001501 // skeletal system development // traceable author statement /// 0001541 // ovarian follicle development // non-traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009605 // response to external stimulus // traceable author statement /// 0030154 // cell differentiation // traceable author statement /// 0030218 // erythrocyte differentiation // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // traceable author statement /// 0042541 // hemoglobin biosynthetic process // inferred from direct assay /// 0045077 // negative regulation of interferon-gamma biosynthetic process // traceable author statement /// 0045578 // negative regulation of B cell differentiation // traceable author statement /// 0045650 // negative regulation of macrophage differentiation // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0046881 // positive regulation of follicle-stimulating hormone secretion // traceable author statement /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0051726 // regulation of cell cycle // inferred from direct assay 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0034673 // inhibin-betaglycan-ActRII complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043512 // inhibin A complex // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0034711 // inhibin binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210142_x_at AF117234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF117234.1 /DEF=Homo sapiens flotillin mRNA, complete cds. /FEA=mRNA /PROD=flotillin /DB_XREF=gi:6563241 /UG=Hs.179986 flotillin 1 /FL=gb:AF117234.1 AF117234 flotillin 1 FLOT1 10211 NM_005803 /// XM_005248780 /// XM_005248781 /// XM_005272759 /// XM_005272760 /// XM_005274909 /// XM_005274910 /// XM_005275335 /// XM_005275336 /// XM_005275502 /// XM_005275503 /// XM_006714947 /// XM_006725465 /// XM_006725672 /// XM_006725971 /// XM_006726072 0007409 // axonogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016600 // flotillin complex // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 210143_at AF196478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF196478.1 /DEF=Homo sapiens annexin 14 (ANX14) mRNA, complete cds. /FEA=mRNA /GEN=ANX14 /PROD=annexin 14 /DB_XREF=gi:6274496 /UG=Hs.188401 annexin A10 /FL=gb:AF196478.1 gb:NM_007193.2 AF196478 annexin A10 ANXA10 11199 NM_007193 /// XM_006714073 0005739 // mitochondrion // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation 210144_at AK000851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000851.1 /DEF=Homo sapiens cDNA FLJ20844 fis, clone ADKA01904. /FEA=mRNA /DB_XREF=gi:7021173 /UG=Hs.20017 chromosome 22 open reading frame 4 /FL=gb:BC002743.1 AK000851 TBC1 domain family, member 22A TBC1D22A 25771 NM_001284303 /// NM_001284304 /// NM_001284305 /// NM_014346 /// NR_104292 /// XM_005261496 /// XM_006724223 /// XR_244364 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 210145_at M68874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M68874.1 /DEF=Homo sapiens phosphatidylcholine 2-acylhydrolase (cPLA2) mRNA, complete cds. /FEA=mRNA /GEN=cPLA2 /PROD=phosphatidylcholine 2-acylhydrolase /DB_XREF=gi:190003 /UG=Hs.211587 phospholipase A2, group IVA (cytosolic, calcium-dependent) /FL=gb:M68874.1 gb:M72393.1 M68874 phospholipase A2, group IVA (cytosolic, calcium-dependent) PLA2G4A 5321 NM_024420 /// XM_005245267 /// XM_005245268 /// XR_426785 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006663 // platelet activating factor biosynthetic process // non-traceable author statement /// 0006690 // icosanoid metabolic process // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046456 // icosanoid biosynthetic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0004622 // lysophospholipase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0004623 // phospholipase A2 activity // non-traceable author statement /// 0004623 // phospholipase A2 activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // not recorded 210146_x_at AF004231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004231.1 /DEF=Homo sapiens monocytemacrophage Ig-related receptor MIR-10 (MIR cl-10) mRNA, complete cds. /FEA=mRNA /GEN=MIR cl-10 /PROD=MIR-10 /DB_XREF=gi:2343110 /UG=Hs.22405 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 /FL=gb:AF000574.1 gb:AF004231.1 gb:AF011565.1 AF004231 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 LILRB2 10288 NM_001080978 /// NM_001278403 /// NM_001278404 /// NM_001278405 /// NM_001278406 /// NM_005874 /// NR_103521 /// XM_006722966 /// XM_006722967 /// XM_006722968 /// XM_006722969 /// XM_006722970 /// XM_006726139 /// XM_006726140 /// XM_006726141 /// XM_006726142 /// XM_006726143 /// XM_006726170 /// XM_006726237 /// XM_006726238 /// XM_006726239 /// XM_006726240 /// XM_006726241 /// XM_006726242 /// XM_006726243 /// XM_006726244 /// XM_006726245 /// XR_430186 /// XR_431049 /// XR_431085 0002376 // immune system process // inferred from electronic annotation /// 0002578 // negative regulation of antigen processing and presentation // inferred from direct assay /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from mutant phenotype /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0032755 // positive regulation of interleukin-6 production // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from mutant phenotype /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2001198 // regulation of dendritic cell differentiation // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from physical interaction /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0032396 // inhibitory MHC class I receptor activity // inferred from direct assay /// 0032396 // inhibitory MHC class I receptor activity // inferred from mutant phenotype /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 210147_at U47054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U47054.1 /DEF=Human putative mono-ADP-ribosyltransferase (htMART) mRNA, complete cds. /FEA=mRNA /GEN=htMART /PROD=mono-ADP-ribosyltransferase /DB_XREF=gi:1226245 /UG=Hs.24976 ADP-ribosyltransferase 3 /FL=gb:U47054.1 gb:NM_001179.1 U47054 ADP-ribosyltransferase 3 ART3 419 NM_001130016 /// NM_001130017 /// NM_001179 /// XM_005262997 /// XM_005262999 /// XM_005263002 /// XM_005263003 /// XM_005263004 /// XM_005263005 /// XM_006714218 /// XM_006714219 /// XM_006714220 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0003956 // NAD(P)+-protein-arginine ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210148_at AF305239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF305239.1 /DEF=Homo sapiens Fas-interacting serinethreonine kinase 3 (FIST3) mRNA, complete cds. /FEA=mRNA /GEN=FIST3 /PROD=Fas-interacting serinethreonine kinase 3 /DB_XREF=gi:10998781 /UG=Hs.30148 homeodomain-interacting protein kinase 3 /FL=gb:AF305239.1 AF305239 homeodomain interacting protein kinase 3 HIPK3 10114 NM_001048200 /// NM_001278162 /// NM_001278163 /// NM_005734 /// XM_005252729 /// XM_006718120 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009299 // mRNA transcription // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 210149_s_at AF061735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061735.1 /DEF=Homo sapiens clone 023e08 My032 protein mRNA, complete cds. /FEA=mRNA /PROD=My032 protein /DB_XREF=gi:12002005 /UG=Hs.307099 Homo sapiens clone 023e08 My032 protein mRNA, complete cds /FL=gb:AF061735.1 AF061735 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d ATP5H 10476 NM_001003785 /// NM_006356 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 210150_s_at BC003355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003355.1 /DEF=Homo sapiens, clone MGC:5311, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5311) /DB_XREF=gi:13097167 /UG=Hs.312953 Homo sapiens, clone MGC:5311, mRNA, complete cds /FL=gb:BC003355.1 BC003355 laminin, alpha 5 LAMA5 3911 NM_005560 /// XM_006723796 /// XM_006723797 /// XM_006723798 0001525 // angiogenesis // non-traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from electronic annotation /// 0008037 // cell recognition // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0009790 // embryo development // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // non-traceable author statement /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0048041 // focal adhesion assembly // non-traceable author statement /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // non-traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0043259 // laminin-10 complex // inferred from direct assay /// 0043259 // laminin-10 complex // traceable author statement /// 0043260 // laminin-11 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred by curator /// 0005515 // protein binding // inferred from electronic annotation 210151_s_at AF186773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF186773.1 /DEF=Homo sapiens regulatory erythroid kinase long form (RED) mRNA, alternatively spliced product, complete cds. /FEA=mRNA /GEN=RED /PROD=regulatory erythroid kinase long form /DB_XREF=gi:10441414 /UG=Hs.38018 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 /FL=gb:AF186773.1 gb:NM_003582.1 AF186773 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 DYRK3 8444 NM_001004023 /// NM_003582 /// XM_005273315 /// XM_005273316 /// XM_006711576 /// XM_006711577 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210152_at U82979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82979.1 /DEF=Human immunoglobulin-like transcript-3 mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript-3 /DB_XREF=gi:1857460 /UG=Hs.67846 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 /FL=gb:U82979.1 gb:U91925.1 gb:AF025532.1 gb:NM_006847.1 U82979 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 LILRB4 11006 NM_001081438 /// NM_001278426 /// NM_001278427 /// NM_001278428 /// NM_001278429 /// NM_001278430 /// NM_006847 /// XM_005277050 /// XM_005277282 /// XM_005277284 /// XM_006726145 /// XM_006726257 /// XM_006726292 /// XM_006726293 0002376 // immune system process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210153_s_at M55905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55905.1 /DEF=Human mitochondrial NAD(P)+ dependent malic enzyme mRNA, complete cds. /FEA=mRNA /GEN=NAD(P)+ -dependent malic enzyme /PROD=mitochondrial NAD(P)+ -dependent malic enzyme /DB_XREF=gi:187299 /UG=Hs.75342 malic enzyme 2, NAD(+)-dependent, mitochondrial /FL=gb:NM_002396.2 gb:M55905.1 M55905 malic enzyme 2, NAD(+)-dependent, mitochondrial ME2 4200 NM_001168335 /// NM_002396 0006108 // malate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // inferred from electronic annotation /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210154_at M55905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55905.1 /DEF=Human mitochondrial NAD(P)+ dependent malic enzyme mRNA, complete cds. /FEA=mRNA /GEN=NAD(P)+ -dependent malic enzyme /PROD=mitochondrial NAD(P)+ -dependent malic enzyme /DB_XREF=gi:187299 /UG=Hs.75342 malic enzyme 2, NAD(+)-dependent, mitochondrial /FL=gb:NM_002396.2 gb:M55905.1 M55905 malic enzyme 2, NAD(+)-dependent, mitochondrial ME2 4200 NM_001168335 /// NM_002396 0006108 // malate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // inferred from electronic annotation /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210155_at D88214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D88214.1 /DEF=Homo sapiens mRNA for myocilin, complete cds. /FEA=mRNA /PROD=myocilin /DB_XREF=gi:2627176 /UG=Hs.78454 myocilin, trabecular meshwork inducible glucocorticoid response /FL=gb:AF001620.1 gb:D88214.1 gb:U85257.1 gb:NM_000261.1 D88214 myocilin, trabecular meshwork inducible glucocorticoid response MYOC 4653 NM_000261 0001649 // osteoblast differentiation // inferred from direct assay /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014734 // skeletal muscle hypertrophy // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from direct assay /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0038133 // ERBB2-ERBB3 signaling pathway // inferred from sequence or structural similarity /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0045162 // clustering of voltage-gated sodium channels // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051901 // positive regulation of mitochondrial depolarization // inferred from direct assay /// 0060348 // bone development // inferred from sequence or structural similarity /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032027 // myosin light chain binding // inferred from physical interaction 210156_s_at D25547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D25547.1 /DEF=Homo sapiens mRNA for PIMT isozyme I, complete cds. /FEA=mRNA /PROD=PIMT isozyme I /DB_XREF=gi:1332402 /UG=Hs.79137 protein-L-isoaspartate (D-aspartate) O-methyltransferase /FL=gb:D25547.1 D25547 protein-L-isoaspartate (D-aspartate) O-methyltransferase PCMT1 5110 NM_001252049 /// NM_001252050 /// NM_001252051 /// NM_001252052 /// NM_001252053 /// NM_005389 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006479 // protein methylation // traceable author statement /// 0030091 // protein repair // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 210157_at AW003989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003989 /FEA=EST /DB_XREF=gi:5850905 /DB_XREF=est:wq94f01.x1 /CLONE=IMAGE:2479705 /UG=Hs.7943 RPB5-mediating protein /FL=gb:AF091095.1 AW003989 URI1, prefoldin-like chaperone URI1 8725 NM_001252641 /// NM_003796 /// NM_134447 /// NR_045557 /// XM_005259362 /// XM_005259363 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001558 // regulation of cell growth // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0009615 // response to virus // inferred from mutant phenotype /// 0010923 // negative regulation of phosphatase activity // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016272 // prefoldin complex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 210158_at U64315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U64315.1 /DEF=Human DNA repair endonuclease subunit (XPF) mRNA, complete cds. /FEA=mRNA /GEN=XPF /PROD=DNA repair endonuclease subunit /DB_XREF=gi:1524410 /UG=Hs.89296 excision repair cross-complementing rodent repair deficiency, complementation group 4 /FL=gb:U64315.1 gb:NM_005236.1 U64315 excision repair cross-complementation group 4 ERCC4 2072 NM_005236 /// XR_243267 /// XR_429638 0000710 // meiotic mismatch repair // /// 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // not recorded /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from mutant phenotype /// 0009650 // UV protection // inferred from electronic annotation /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0033683 // nucleotide-excision repair, DNA incision // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 1901255 // nucleotide-excision repair involved in interstrand cross-link repair // not recorded 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0000110 // nucleotide-excision repair factor 1 complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation 0000014 // single-stranded DNA endodeoxyribonuclease activity // not recorded /// 0001094 // TFIID-class transcription factor binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from mutant phenotype /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043566 // structure-specific DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 210159_s_at AF230386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230386.1 /DEF=Homo sapiens tripartite motif protein TRIM31 alpha mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM31 alpha /DB_XREF=gi:12275859 /UG=Hs.91096 ring finger protein /FL=gb:AF230386.1 AF230386 tripartite motif containing 31 TRIM31 11074 NM_007028 /// NM_052816 /// XM_006714977 /// XM_006714978 /// XM_006725470 /// XM_006725685 /// XM_006725686 /// XM_006725687 /// XM_006725804 /// XM_006725805 /// XM_006725806 /// XM_006725894 /// XM_006725895 /// XM_006725983 /// XM_006725984 /// XM_006726074 /// XM_006726075 /// XR_427824 /// XR_430855 /// XR_430933 /// XR_430971 /// XR_430994 /// XR_430995 /// XR_431012 /// XR_431041 /// XR_431042 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210160_at BC000398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000398.1 /DEF=Homo sapiens, platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD), clone MGC:8519, mRNA, complete cds. /FEA=mRNA /PROD=platelet-activating factor acetylhydrolase,isoform Ib, beta subunit (30kD) /DB_XREF=gi:12653258 /UG=Hs.93354 platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD) /FL=gb:BC000398.1 gb:D63390.1 gb:NM_002572.1 BC000398 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) PAFAH1B2 5049 NM_001184746 /// NM_001184747 /// NM_001184748 /// NM_002572 /// NR_110268 /// NR_110269 /// NR_110282 0006629 // lipid metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210161_at U08015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U08015.1 /DEF=Human NF-ATc mRNA, complete cds. /FEA=mRNA /PROD=NF-ATc /DB_XREF=gi:500631 /UG=Hs.96149 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 /FL=gb:U08015.1 U08015 210162_s_at U08015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U08015.1 /DEF=Human NF-ATc mRNA, complete cds. /FEA=mRNA /PROD=NF-ATc /DB_XREF=gi:500631 /UG=Hs.96149 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 /FL=gb:U08015.1 U08015 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 4772 NM_001278669 /// NM_001278670 /// NM_001278672 /// NM_001278673 /// NM_001278675 /// NM_006162 /// NM_172387 /// NM_172388 /// NM_172389 /// NM_172390 /// XM_006722477 /// XM_006722478 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from sequence or structural similarity 210163_at AF030514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF030514.1 /DEF=Homo sapiens interferon stimulated T-cell alpha chemoattractant precursor, mRNA, complete cds. /FEA=mRNA /PROD=interferon stimulated T-cell alphachemoattractant precursor /DB_XREF=gi:3219692 /UG=Hs.103982 small inducible cytokine subfamily B (Cys-X-Cys), member 11 /FL=gb:BC005292.1 gb:AF030514.1 gb:U66096.1 gb:NM_005409.2 AF030514 chemokine (C-X-C motif) ligand 11 CXCL11 6373 NM_005409 0006935 // chemotaxis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010818 // T cell chemotaxis // inferred from mutant phenotype /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 210164_at J03189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03189.1 /DEF=Human proteolytic serine esterase-like protein (SECT) gene, complete cds. /FEA=mRNA /DB_XREF=gi:338010 /UG=Hs.1051 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) /FL=gb:J04071.1 gb:J03189.1 gb:M17016.1 gb:NM_004131.2 J03189 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) GZMB 3002 NM_004131 0006508 // proteolysis // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008626 // granzyme-mediated apoptotic signaling pathway // not recorded /// 0019835 // cytolysis // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // not recorded /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 210165_at M55983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55983.1 /DEF=Human DNase I mRNA, complete cds. /FEA=mRNA /GEN=DNase I /PROD=DNase I /DB_XREF=gi:181623 /UG=Hs.113221 deoxyribonuclease I /FL=gb:M55983.1 gb:NM_005223.1 M55983 deoxyribonuclease I DNASE1 1773 NM_005223 /// XM_005255148 /// XM_005255149 /// XM_006720852 /// XM_006720853 /// XM_006720854 /// XM_006720855 /// XR_243264 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004530 // deoxyribonuclease I activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation 210166_at AF051151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051151.1 /DEF=Homo sapiens Tollinterleukin-1 receptor-like protein 3 (TIL3) mRNA, complete cds. /FEA=mRNA /GEN=TIL3 /PROD=Tollinterleukin-1 receptor-like protein 3 /DB_XREF=gi:3132525 /UG=Hs.114408 toll-like receptor 5 /FL=gb:AF051151.1 AF051151 toll-like receptor 5 TLR5 7100 NM_003268 /// XM_005273241 /// XM_005273242 /// XM_005273243 /// XM_006711503 /// XM_006711504 /// XM_006711505 /// XM_006711506 /// XM_006711507 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0034123 // positive regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 210167_s_at U06935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U06935.1 /DEF=Human thyrotroph embryonic factor (TEF) mRNA, complete cds. /FEA=mRNA /GEN=TEF /PROD=thyrotroph embryonic factor /DB_XREF=gi:606796 /UG=Hs.121481 thyrotrophic embryonic factor /FL=gb:U44059.1 gb:NM_003216.1 gb:U06935.1 U06935 thyrotrophic embryonic factor TEF 7008 NM_001145398 /// NM_003216 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210168_at J05064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J05064.1 /DEF=Human complement component C6 mRNA, complete cds. /FEA=mRNA /GEN=C6 /DB_XREF=gi:179703 /UG=Hs.1282 complement component 6 /FL=gb:J05064.1 gb:J05024.1 gb:NM_000065.1 J05064 complement component 6 C6 729 NM_000065 /// NM_001115131 /// XM_005248356 /// XM_005248357 /// XM_006714496 /// XM_006714497 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001970 // positive regulation of activation of membrane attack complex // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045917 // positive regulation of complement activation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210169_at AB007880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007880.1 /DEF=Homo sapiens KIAA0420 mRNA, complete cds. /FEA=mRNA /GEN=KIAA0420 /DB_XREF=gi:2887414 /UG=Hs.129883 KIAA0420 gene product /FL=gb:AB007880.1 AB007880 SEC14-like 5 (S. cerevisiae) SEC14L5 9717 NM_014692 0006810 // transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 210170_at BC001017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001017.1 /DEF=Homo sapiens, Similar to alpha-actinin-2-associated LIM protein, clone MGC:2005, mRNA, complete cds. /FEA=mRNA /PROD=Similar to alpha-actinin-2-associated LIMprotein /DB_XREF=gi:12654386 /UG=Hs.135281 alpha-actinin-2-associated LIM protein /FL=gb:BC001017.1 BC001017 PDZ and LIM domain 3 PDLIM3 27295 NM_001114107 /// NM_001257962 /// NM_001257963 /// NM_014476 /// NR_047562 0007015 // actin filament organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210171_s_at S68134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S68134.1 /DEF=Homo sapiens cyclic AMP-responsive element modulator beta isoform (CREM) mRNA, complete cds. /FEA=mRNA /GEN=CREM /PROD=cyclic AMP-responsive element modulator betaisoform /DB_XREF=gi:545206 /UG=Hs.155924 cAMP responsive element modulator /FL=gb:S68134.1 S68134 cAMP responsive element modulator CREM 1390 NM_001267562 /// NM_001267563 /// NM_001267564 /// NM_001267565 /// NM_001267566 /// NM_001267567 /// NM_001267568 /// NM_001267569 /// NM_001267570 /// NM_001881 /// NM_181571 /// NM_182717 /// NM_182718 /// NM_182719 /// NM_182720 /// NM_182721 /// NM_182722 /// NM_182723 /// NM_182724 /// NM_182725 /// NM_182769 /// NM_182770 /// NM_182771 /// NM_182772 /// NM_182850 /// NM_182853 /// NM_183011 /// NM_183012 /// NM_183013 /// NM_183060 /// NR_051971 /// NR_051972 /// NR_051973 /// NR_051974 /// NR_051975 /// XM_006717378 /// XM_006717379 /// XM_006717380 /// XM_006717381 /// XM_006717382 /// XM_006717383 /// XM_006717384 /// XM_006717385 /// XM_006717386 /// XM_006717387 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210172_at D26121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D26121.1 /DEF=Human mRNA for ZFM1 protein alternatively spliced product, complete cds. /FEA=mRNA /PROD=ZFM1 protein, alternatively spliced product /DB_XREF=gi:785998 /UG=Hs.169303 Human mRNA for ZFM1 protein alternatively spliced product, complete cds /FL=gb:D26121.1 D26121 splicing factor 1 SF1 7536 NM_001178030 /// NM_001178031 /// NM_004630 /// NM_201995 /// NM_201997 /// NM_201998 /// NR_033649 /// NR_033650 /// XM_006718681 /// XM_006718682 /// XM_006718683 /// XM_006718684 /// XM_006718685 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005840 // ribosome // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210173_at D37781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D37781.1 /DEF=Human mRNA for protein-tyrosine phosphatase HPTPeta, complete cds. /FEA=mRNA /PROD=protein-tyrosine phosphatase /DB_XREF=gi:633072 /UG=Hs.171992 protein tyrosine phosphatase, receptor type, J /FL=gb:U10886.1 gb:NM_002843.1 gb:D37781.1 D37781 protein tyrosine phosphatase, receptor type, J PTPRJ 5795 NM_001098503 /// NM_002843 /// XM_006718269 0001570 // vasculogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010572 // positive regulation of platelet activation // inferred from electronic annotation /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060242 // contact inhibition // non-traceable author statement /// 2000272 // negative regulation of receptor activity // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0016791 // phosphatase activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction /// 0070097 // delta-catenin binding // inferred from physical interaction 210174_at AF228413 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF228413.1 /DEF=Homo sapiens hepatocyte transcription factor mRNA, 3UTR. /FEA=mRNA /DB_XREF=gi:7677372 /UG=Hs.183123 nuclear receptor subfamily 5, group A, member 2 /FL=gb:U93553.1 gb:AB019246.1 gb:AF124247.1 AF228413 nuclear receptor subfamily 5, group A, member 2 NR5A2 2494 NM_001276464 /// NM_003822 /// NM_205860 /// XM_005245061 /// XM_005245062 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0009790 // embryo development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031018 // endocrine pancreas development // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210175_at BC000853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000853.1 /DEF=Homo sapiens, Similar to chromosome 2 open reading frame 3, clone MGC:4994, mRNA, complete cds. /FEA=mRNA /PROD=Similar to chromosome 2 open reading frame 3 /DB_XREF=gi:12654086 /UG=Hs.184175 chromosome 2 open reading frame 3 /FL=gb:BC000853.1 BC000853 GC-rich sequence DNA-binding factor 2 GCFC2 6936 NM_001201334 /// NM_001201335 /// NM_003203 /// XM_005264520 /// XM_005264521 /// XR_426995 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 210176_at AL050262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL050262.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I0682 (from clone DKFZp564I0682); complete cds. /FEA=mRNA /GEN=DKFZp564I0682 /PROD=hypothetical protein /DB_XREF=gi:4886482 /UG=Hs.2474 toll-like receptor 1 /FL=gb:U88540.1 gb:D13637.1 gb:NM_003263.1 gb:AL050262.1 AL050262 toll-like receptor 1 TLR1 7096 NM_003263 /// XM_005262662 /// XM_005262663 /// XM_005262665 /// XM_005262666 /// XM_006714028 0002224 // toll-like receptor signaling pathway // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0034130 // toll-like receptor 1 signaling pathway // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034150 // toll-like receptor 6 signaling pathway // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042116 // macrophage activation // non-traceable author statement /// 0042495 // detection of triacyl bacterial lipopeptide // inferred from direct assay /// 0042496 // detection of diacyl bacterial lipopeptide // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from sequence or structural similarity /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0071727 // cellular response to triacyl bacterial lipopeptide // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035354 // Toll-like receptor 1-Toll-like receptor 2 protein complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 210177_at U34249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34249.1 /DEF=Human putative zinc finger protein (ZNFB7) mRNA, complete cds. /FEA=mRNA /GEN=ZNFB7 /PROD=zinc finger protein /DB_XREF=gi:4096653 /UG=Hs.274295 ring finger protein 9 /FL=gb:AF220132.1 gb:U34249.1 U34249 tripartite motif containing 15 TRIM15 89870 NM_033229 /// NM_052812 /// XM_005249471 /// XM_005272907 /// XM_005274898 /// XM_005275063 /// XM_005275195 /// XM_005275319 /// XM_005275490 /// XM_005275628 0007500 // mesodermal cell fate determination // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype /// 1901253 // negative regulation of intracellular transport of viral material // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210178_x_at AF047448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047448.1 /DEF=Homo sapiens TLS-associated protein TASR mRNA, complete cds. /FEA=mRNA /PROD=TLS-associated protein TASR /DB_XREF=gi:2961148 /UG=Hs.288038 TLS-associated serine-arginine protein 1 /FL=gb:BC001107.1 gb:AF047448.1 AF047448 serine/arginine-rich splicing factor 10 SRSF10 10772 NM_001191005 /// NM_001191006 /// NM_001191007 /// NM_001191009 /// NM_006625 /// NM_054016 /// NR_034035 /// XM_006710298 /// XM_006710299 /// XM_006710300 /// XM_006710301 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 210179_at AJ007557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ007557.1 /DEF=Homo sapiens mRNA for inwardly-rectifying potassium channel Kir7.1. /FEA=mRNA /GEN=Kir7.1 /PROD=inwardly-rectifying potassium channel /DB_XREF=gi:3650319 /UG=Hs.296361 potassium inwardly-rectifying channel,subfamily J, member 13 /FL=gb:AF061118.1 gb:AB013891.1 AJ007557 potassium inwardly-rectifying channel, subfamily J, member 13 KCNJ13 3769 NM_001172416 /// NM_001172417 /// NM_002242 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // non-traceable author statement 0008076 // voltage-gated potassium channel complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // non-traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 210180_s_at U87836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87836.1 /DEF=Homo sapiens htra2-beta-2 mRNA, complete cds. /FEA=mRNA /PROD=htra2-beta-2 /DB_XREF=gi:2367403 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:U87836.1 U87836 transformer 2 beta homolog (Drosophila) TRA2B 6434 NM_001243879 /// NM_004593 /// XM_005247703 /// XM_006713724 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210181_s_at AF169148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF169148.1 /DEF=Homo sapiens s-CaBP1 (CABP1) mRNA, complete cds. /FEA=mRNA /GEN=CABP1 /PROD=s-CaBP1 /DB_XREF=gi:6708059 /UG=Hs.301423 calcium binding protein 1 (calbrain) /FL=gb:AF169148.1 AF169148 calcium binding protein 1 CABP1 9478 NM_001033677 /// NM_004276 /// NM_031205 /// XM_005253994 0010651 // negative regulation of cell communication by electrical coupling // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210182_at AB000263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000263.1 /DEF=Homo sapiens mRNA for prepro cortistatin like peptide, complete cds. /FEA=mRNA /PROD=prepro cortistatin like peptide /DB_XREF=gi:2055231 /UG=Hs.44205 cortistatin /FL=gb:AB000263.1 gb:AF013252.1 gb:NM_001302.1 AB000263 cortistatin CORT 1325 NM_001302 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay /// 0071821 // FANCM-MHF complex // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210183_x_at AF112222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112222.1 /DEF=Homo sapiens nuclear protein SDK3 mRNA, complete cds. /FEA=mRNA /PROD=nuclear protein SDK3 /DB_XREF=gi:6563229 /UG=Hs.44499 pinin, desmosome associated protein /FL=gb:AF112222.1 AF112222 pinin, desmosome associated protein PNN 5411 NM_002687 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 210184_at M81695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81695.1 /DEF=H.sapiens leukocyte adhesion glycoprotein p150,95 mRNA, complete cds. /FEA=mRNA /GEN=ITGAX /DB_XREF=gi:487829 /UG=Hs.51077 integrin, alpha X (antigen CD11C (p150), alpha polypeptide) /FL=gb:M81695.1 gb:NM_000887.2 M81695 integrin, alpha X (complement component 3 receptor 4 subunit) ITGAX 3687 NM_000887 /// NM_001286375 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210185_at AB054985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB054985.1 /DEF=Homo sapiens mRNA for voltage-dependent calcium channel beta-1b subunit, complete cds. /FEA=mRNA /PROD=voltage-dependent calcium channel beta-1bsubunit /DB_XREF=gi:12483679 /UG=Hs.635 calcium channel, voltage-dependent, beta 1 subunit /FL=gb:AB054985.1 gb:L06110.1 gb:M92303.1 AB054985 calcium channel, voltage-dependent, beta 1 subunit CACNB1 782 NM_000723 /// NM_199247 /// NM_199248 /// XM_005257645 /// XM_005257646 /// XM_005257647 /// XM_006722072 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from electronic annotation 210186_s_at BC005147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005147.1 /DEF=Homo sapiens, FK506-binding protein 1A (12kD), clone MGC:2167, mRNA, complete cds. /FEA=mRNA /PROD=FK506-binding protein 1A (12kD) /DB_XREF=gi:13477342 /UG=Hs.752 FK506-binding protein 1A (12kD) /FL=gb:BC005147.1 BC005147 FK506 binding protein 1A, 12kDa /// uncharacterized LOC101929368 FKBP1A /// LOC101929368 2280 /// 101929368 NM_000801 /// NM_001199786 /// NM_054014 /// XR_245428 /// XR_247917 /// XR_253167 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0018208 // peptidyl-proline modification // /// 0022417 // protein maturation by protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from genetic interaction /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded /// 0070588 // calcium ion transmembrane transport // non-traceable author statement /// 1902991 // regulation of amyloid precursor protein catabolic process // inferred from genetic interaction /// 1990000 // amyloid fibril formation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030424 // axon // /// 0033017 // sarcoplasmic reticulum membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005527 // macrolide binding // non-traceable author statement /// 0005528 // FK506 binding // inferred from direct assay /// 0005528 // FK506 binding // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 210187_at BC005147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005147.1 /DEF=Homo sapiens, FK506-binding protein 1A (12kD), clone MGC:2167, mRNA, complete cds. /FEA=mRNA /PROD=FK506-binding protein 1A (12kD) /DB_XREF=gi:13477342 /UG=Hs.752 FK506-binding protein 1A (12kD) /FL=gb:BC005147.1 BC005147 FK506 binding protein 1A, 12kDa /// uncharacterized LOC101929368 FKBP1A /// LOC101929368 2280 /// 101929368 NM_000801 /// NM_001199786 /// NM_054014 /// XR_245428 /// XR_247917 /// XR_253167 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0018208 // peptidyl-proline modification // /// 0022417 // protein maturation by protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from genetic interaction /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded /// 0070588 // calcium ion transmembrane transport // non-traceable author statement /// 1902991 // regulation of amyloid precursor protein catabolic process // inferred from genetic interaction /// 1990000 // amyloid fibril formation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030424 // axon // /// 0033017 // sarcoplasmic reticulum membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005527 // macrolide binding // non-traceable author statement /// 0005528 // FK506 binding // inferred from direct assay /// 0005528 // FK506 binding // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 210188_at D13318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13318.1 /DEF=Human mRNA for transcription factor, E4TF1-60, complete cds. /FEA=mRNA /PROD=E4TF1-60 /DB_XREF=gi:286026 /UG=Hs.78 GA-binding protein transcription factor, alpha subunit (60kD) /FL=gb:D13318.1 gb:NM_002040.1 gb:U13044.1 D13318 GA binding protein transcription factor, alpha subunit 60kDa GABPA 2551 NM_001197297 /// NM_002040 /// XM_005260938 /// XM_005260939 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 210189_at D85730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D85730.1 /DEF=Homo sapiens HSPA1L mRNA for Heat shock protein 70 testis variant, complete cds. /FEA=mRNA /GEN=HSPA1L /PROD=Heat shock protein 70 testis variant /DB_XREF=gi:3461865 /UG=Hs.80288 heat shock 70kD protein-like 1 /FL=gb:D85730.1 gb:NM_005527.1 D85730 heat shock 70kDa protein 1-like HSPA1L 3305 NM_005527 /// XM_005249070 /// XM_005249071 /// XM_005249073 /// XM_005272813 /// XM_005272816 /// XM_005272817 /// XM_005274859 /// XM_005274861 /// XM_005274862 /// XM_005274970 /// XM_005274973 /// XM_005274974 /// XM_005275399 /// XM_005275401 /// XM_005275402 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay 210190_at AF071504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF071504.1 /DEF=Homo sapiens syntaxin 11 mRNA, complete cds. /FEA=mRNA /PROD=syntaxin 11 /DB_XREF=gi:3243239 /UG=Hs.118958 syntaxin 11 /FL=gb:AF071504.1 gb:AF044309.1 gb:AF038898.1 gb:NM_003764.1 AF071504 syntaxin 11 STX11 8676 NM_003764 /// XM_005267189 /// XM_006715588 0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210191_s_at BC002447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002447.1 /DEF=Homo sapiens, Similar to putative homeodomain transcription factor, clone MGC:1307, mRNA, complete cds. /FEA=mRNA /PROD=Similar to putative homeodomain transcriptionfactor /DB_XREF=gi:12803264 /UG=Hs.123637 putative homeodomain transcription factor /FL=gb:BC002447.1 BC002447 putative homeodomain transcription factor 1 PHTF1 10745 NM_006608 /// XM_005270383 /// XM_005270384 /// XM_005270385 /// XM_005270387 /// XM_006710296 /// XM_006710297 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 210192_at AB013452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013452.1 /DEF=Homo sapiens mRNA for ATPaseII, complete cds. /FEA=mRNA /PROD=ATPaseII /DB_XREF=gi:4704323 /UG=Hs.144931 ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1 /FL=gb:AB013452.1 AB013452 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 ATP8A1 10396 NM_001105529 /// NM_006095 /// XM_005248043 /// XM_006713989 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0015917 // aminophospholipid transport // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015247 // aminophospholipid transporter activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210193_at D28114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28114.1 /DEF=Human mRNA for MOBP (myelin-associated oligodendrocytic basic protein), complete cds, clone hOPRP2. /FEA=mRNA /PROD=MOBP /DB_XREF=gi:662277 /UG=Hs.169309 myelin-associated oligodendrocyte basic protein /FL=gb:D28114.1 D28114 myelin-associated oligodendrocyte basic protein MOBP 4336 NM_001278322 /// NM_001278323 /// NM_182935 /// NR_003090 /// NR_103504 /// NR_103505 /// NR_103506 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 210194_at U17033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17033.1 /DEF=Human 180 kDa transmembrane PLA2 receptor mRNA, complete cds. /FEA=mRNA /PROD=180 kDa transmembrane PLA2 receptor precursor /DB_XREF=gi:862374 /UG=Hs.171945 phospholipase A2 receptor 1, 180kD /FL=gb:U17033.1 U17033 phospholipase A2 receptor 1, 180kDa PLA2R1 22925 NM_001007267 /// NM_001195641 /// NM_007366 /// XM_005246392 /// XM_005246393 /// XM_005246395 /// XM_006712369 0001816 // cytokine production // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 1900138 // negative regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 1900139 // negative regulation of arachidonic acid secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 210195_s_at M34715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M34715.1 /DEF=Human pregnancy-specific beta-1-glycoprotein mRNA PSG95, complete cds. /FEA=mRNA /PROD=pregnancy-specific beta-1-glycoprotein /DB_XREF=gi:190590 /UG=Hs.173609 pregnancy specific beta-1-glycoprotein 1 /FL=gb:M34715.1 gb:J04539.1 gb:M33663.1 M34715 pregnancy specific beta-1-glycoprotein 1 PSG1 5669 NM_001184825 /// NM_001184826 /// NM_006905 /// XM_005259063 /// XM_005259064 /// XM_005259065 /// XM_005259066 /// XM_005259067 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210196_s_at M33663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33663.1 /DEF=Human pregnancy-specific glycoprotein-1d (PSG-1d) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:190652 /UG=Hs.173609 pregnancy specific beta-1-glycoprotein 1 /FL=gb:M34715.1 gb:J04539.1 gb:M33663.1 M33663 pregnancy specific beta-1-glycoprotein 1 PSG1 5669 NM_001184825 /// NM_001184826 /// NM_006905 /// XM_005259063 /// XM_005259064 /// XM_005259065 /// XM_005259066 /// XM_005259067 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210197_at BC003622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003622.1 /DEF=Homo sapiens, Similar to inositol 1,3,4-triphosphate 56 kinase, clone MGC:2116, mRNA, complete cds. /FEA=mRNA /PROD=Similar to inositol 1,3,4-triphosphate 56kinase /DB_XREF=gi:13177675 /UG=Hs.176677 Homo sapiens, Similar to inositol 1,3,4-triphosphate 56 kinase, clone MGC:2116, mRNA, complete cds /FL=gb:BC003622.1 BC003622 inositol-tetrakisphosphate 1-kinase ITPK1 3705 NM_001142593 /// NM_001142594 /// NM_014216 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047325 // inositol tetrakisphosphate 1-kinase activity // traceable author statement /// 0052725 // inositol-1,3,4-trisphosphate 6-kinase activity // traceable author statement /// 0052726 // inositol-1,3,4-trisphosphate 5-kinase activity // traceable author statement /// 0052825 // inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity // traceable author statement /// 0052830 // inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity // traceable author statement /// 0052831 // inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity // traceable author statement /// 0052835 // inositol-3,4,6-trisphosphate 1-kinase activity // traceable author statement 210198_s_at BC002665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002665.1 /DEF=Homo sapiens, proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated), clone MGC:3940, mRNA, complete cds. /FEA=mRNA /PROD=proteolipid protein (Pelizaeus-Merzbacherdisease, spastic paraplegia 2, uncomplicated) /DB_XREF=gi:12803660 /UG=Hs.1787 proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) /FL=gb:BC002665.1 gb:M17085.1 BC002665 proteolipid protein 1 PLP1 5354 NM_000533 /// NM_001128834 /// NM_199478 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008366 // axon ensheathment // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0019911 // structural constituent of myelin sheath // inferred from electronic annotation 210199_at U66584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66584.1 /DEF=Human alphaA-crystallin (CRYAA) mRNA, complete cds. /FEA=mRNA /GEN=CRYAA /PROD=alphaA-crystallin /DB_XREF=gi:1732062 /UG=Hs.184085 crystallin, alpha A /FL=gb:U66584.1 gb:NM_000394.1 gb:U05569.1 U66584 crystallin, alpha A CRYAA 1409 NM_000394 /// XM_005261093 0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032387 // negative regulation of intracellular transport // inferred from direct assay /// 0042026 // protein refolding // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060561 // apoptotic process involved in morphogenesis // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from electronic annotation /// 0070309 // lens fiber cell morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from mutant phenotype /// 0051082 // unfolded protein binding // inferred from physical interaction 210200_at BC000108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000108.1 /DEF=Homo sapiens, Similar to Nedd-4-like ubiquitin-protein ligase, clone MGC:2079, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Nedd-4-like ubiquitin-protein ligase /DB_XREF=gi:12652716 /UG=Hs.19301 Homo sapiens, Similar to Nedd-4-like ubiquitin-protein ligase, clone MGC:2079, mRNA, complete cds /FL=gb:BC000108.1 BC000108 WW domain containing E3 ubiquitin protein ligase 2 WWP2 11060 NM_001270453 /// NM_001270454 /// NM_001270455 /// NM_007014 /// NM_199424 /// XM_005255778 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046718 // viral entry into host cell // traceable author statement /// 0051224 // negative regulation of protein transport // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 210201_x_at AF001383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001383.1 /DEF=Homo sapiens amphiphysin II mRNA, complete cds. /FEA=mRNA /PROD=amphiphysin II /DB_XREF=gi:2199534 /UG=Hs.193163 bridging integrator 1 /FL=gb:AF001383.1 gb:AF068917.1 AF001383 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 210202_s_at U87558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87558.1 /DEF=Homo sapiens amphiphysin II mRNA, complete cds. /FEA=mRNA /PROD=amphiphysin II /DB_XREF=gi:2160718 /UG=Hs.193163 bridging integrator 1 /FL=gb:U87558.1 gb:AF004015.1 U87558 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 210203_at R64001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R64001 /FEA=EST /DB_XREF=gi:835880 /DB_XREF=est:yi19c06.r1 /CLONE=IMAGE:139690 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:U71268.1 R64001 CCR4-NOT transcription complex, subunit 4 CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210204_s_at U71268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71268.1 /DEF=Human potential transcriptional repressor NOT4Hp (NOT4H) mRNA, complete cds. /FEA=mRNA /GEN=NOT4H /PROD=potential transcriptional repressor NOT4Hp /DB_XREF=gi:4097899 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:U71268.1 U71268 CCR4-NOT transcription complex, subunit 4 CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210205_at AB026730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026730.1 /DEF=Homo sapiens B3GALT4 mRNA for beta-1,3-galactosyltransferase-4, complete cds. /FEA=mRNA /GEN=B3GALT4 /PROD=beta-1,3-galactosyltransferase-4 /DB_XREF=gi:6683013 /UG=Hs.21495 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 /FL=gb:AF063595.1 gb:NM_003782.1 gb:AB026730.1 AB026730 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 B3GALT4 8705 NM_003782 0006486 // protein glycosylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047915 // ganglioside galactosyltransferase activity // inferred from electronic annotation 210206_s_at U33833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U33833.1 /DEF=Human CHL1-related helicase (CHLR1) mRNA, complete cds. /FEA=mRNA /GEN=CHLR1 /PROD=helicase /DB_XREF=gi:1517815 /UG=Hs.27424 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 (S.cerevisiae CHL1-like helicase) /FL=gb:U33833.1 gb:U75967.1 U33833 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 DDX11 1663 NM_001257144 /// NM_001257145 /// NM_004399 /// NM_030653 /// NM_030655 /// NM_152438 /// XM_005253331 /// XM_005253333 /// XM_006719041 /// XM_006719042 /// XM_006719043 /// XM_006719044 /// XM_006719045 /// XM_006719046 /// XM_006719047 /// XM_006719048 /// XM_006719049 /// XM_006719050 /// XM_006719051 /// XM_006719052 /// XM_006719053 /// XR_429031 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000084 // mitotic S phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 210208_x_at BC003133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003133.1 /DEF=Homo sapiens, Similar to HLA-B associated transcript-3, clone MGC:3619, mRNA, complete cds. /FEA=mRNA /PROD=Similar to HLA-B associated transcript-3 /DB_XREF=gi:13111924 /UG=Hs.274348 HLA-B associated transcript-3 /FL=gb:BC003133.1 BC003133 BCL2-associated athanogene 6 BAG6 7917 NM_001098534 /// NM_001199697 /// NM_001199698 /// NM_004639 /// NM_080702 /// NM_080703 /// XM_005249393 /// XM_005249396 /// XM_005272880 /// XM_005272883 /// XM_005275034 /// XM_005275037 /// XM_005275169 /// XM_005275172 /// XM_005275292 /// XM_005275295 /// XM_005275464 /// XM_005275468 /// XM_005275597 /// XM_005275601 /// XM_006715192 /// XM_006715193 /// XM_006715194 /// XM_006715195 /// XM_006715196 /// XM_006715197 /// XM_006715198 /// XM_006715199 /// XM_006715200 /// XM_006715201 /// XM_006715202 /// XM_006715203 /// XM_006725509 /// XM_006725510 /// XM_006725511 /// XM_006725512 /// XM_006725513 /// XM_006725514 /// XM_006725515 /// XM_006725516 /// XM_006725517 /// XM_006725518 /// XM_006725519 /// XM_006725520 /// XM_006725725 /// XM_006725726 /// XM_006725727 /// XM_006725728 /// XM_006725729 /// XM_006725730 /// XM_006725731 /// XM_006725732 /// XM_006725733 /// XM_006725734 /// XM_006725735 /// XM_006725736 /// XM_006725835 /// XM_006725836 /// XM_006725837 /// XM_006725838 /// XM_006725839 /// XM_006725840 /// XM_006725841 /// XM_006725842 /// XM_006725843 /// XM_006725844 /// XM_006725845 /// XM_006725846 /// XM_006725923 /// XM_006725924 /// XM_006725925 /// XM_006725926 /// XM_006725927 /// XM_006725928 /// XM_006725929 /// XM_006725930 /// XM_006725931 /// XM_006725932 /// XM_006725933 /// XM_006725934 /// XM_006726025 /// XM_006726026 /// XM_006726027 /// XM_006726028 /// XM_006726029 /// XM_006726030 /// XM_006726031 /// XM_006726032 /// XM_006726033 /// XM_006726034 /// XM_006726035 /// XM_006726036 /// XM_006726113 /// XM_006726114 /// XM_006726115 /// XM_006726116 /// XM_006726117 /// XM_006726118 /// XM_006726119 /// XM_006726120 /// XM_006726121 /// XM_006726122 /// XM_006726123 /// XM_006726124 0001822 // kidney development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from sequence or structural similarity /// 0043022 // ribosome binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from sequence or structural similarity 210210_at AF181660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF181660.1 /DEF=Homo sapiens immunoglobulin superfamily member WM78 mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin superfamily member WM78 /DB_XREF=gi:6006818 /UG=Hs.287832 myelin protein zero-like 1 /FL=gb:AF181660.1 AF181660 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210211_s_at AF028832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF028832.1 /DEF=Homo sapiens Hsp89-alpha-delta-N mRNA, complete cds. /FEA=mRNA /PROD=Hsp89-alpha-delta-N /DB_XREF=gi:3287488 /UG=Hs.289088 heat shock 90kD protein 1, alpha /FL=gb:AF028832.1 AF028832 heat shock protein 90kDa alpha (cytosolic), class A member 1 HSP90AA1 3320 NM_001017963 /// NM_005348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0030911 // TPR domain binding // inferred from direct assay /// 0030911 // TPR domain binding // traceable author statement /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 210212_x_at BC002600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002600.1 /DEF=Homo sapiens, mature T-cell proliferation 1, clone MGC:2069, mRNA, complete cds. /FEA=mRNA /PROD=mature T-cell proliferation 1 /DB_XREF=gi:12803540 /UG=Hs.3548 mature T-cell proliferation 1 /FL=gb:BC002600.1 BC002600 C-x(9)-C motif containing 4 CMC4 100272147 NM_001018024 0008283 // cell proliferation // traceable author statement 0005739 // mitochondrion // inferred from direct assay 210213_s_at AF022229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022229.1 /DEF=Homo sapiens translation initiation factor 6 (eIF6) mRNA, complete cds. /FEA=mRNA /GEN=eIF6 /PROD=translation initiation factor 6 /DB_XREF=gi:2809382 /UG=Hs.5215 integrin beta 4 binding protein /FL=gb:AF022229.1 AF022229 eukaryotic translation initiation factor 6 EIF6 3692 NM_001267810 /// NM_002212 /// NM_181466 /// NM_181467 /// NM_181468 /// NM_181469 /// NR_052022 /// NR_052023 /// NR_052024 0000054 // ribosomal subunit export from nucleus // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0042273 // ribosomal large subunit biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005638 // lamin filament // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from electronic annotation 210214_s_at U25110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U25110.1 /DEF=Human bone morphogenic protein type II receptor mRNA, complete cds. /FEA=mRNA /PROD=bone morphogenic protein type II receptor /DB_XREF=gi:882390 /UG=Hs.53250 bone morphogenetic protein receptor, type II (serinethreonine kinase) /FL=gb:U25110.1 U25110 bone morphogenetic protein receptor, type II (serine/threonine kinase) BMPR2 659 NM_001204 /// NM_033346 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from mutant phenotype /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032924 // activin receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045906 // negative regulation of vasoconstriction // inferred from sequence or structural similarity /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060836 // lymphatic endothelial cell differentiation // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from sequence or structural similarity /// 0060841 // venous blood vessel development // inferred from sequence or structural similarity /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 1902731 // negative regulation of chondrocyte proliferation // inferred from mutant phenotype /// 2000279 // negative regulation of DNA biosynthetic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from mutant phenotype /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044214 // fully spanning plasma membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016362 // activin receptor activity, type II // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210215_at AF067864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067864.1 /DEF=Homo sapiens transferrin receptor 2 alpha (TFR2) mRNA, complete cds. /FEA=mRNA /GEN=TFR2 /PROD=transferrin receptor 2 alpha /DB_XREF=gi:5596369 /UG=Hs.63758 transferrin receptor 2 /FL=gb:AF067864.1 AF067864 transferrin receptor 2 TFR2 7036 NM_001206855 /// NM_003227 /// XM_005250553 /// XM_005250554 /// XM_006716103 0006508 // proteolysis // inferred from electronic annotation /// 0006826 // iron ion transport // non-traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004998 // transferrin receptor activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation 210216_x_at AF084513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF084513.1 /DEF=Homo sapiens DNA repair exonuclease (REC1) mRNA, alternatively spliced product, complete cds. /FEA=mRNA /GEN=REC1 /PROD=DNA repair exonuclease /DB_XREF=gi:3600078 /UG=Hs.7179 RAD1 (S. pombe) homolog /FL=gb:AF084513.1 gb:AF090170.1 AF084513 RAD1 homolog (S. pombe) RAD1 5810 NM_001033673 /// NM_002853 /// NM_133282 /// NM_133377 /// NR_026591 0000075 // cell cycle checkpoint // non-traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007128 // meiotic prophase I // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003684 // damaged DNA binding // non-traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210218_s_at U36501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36501.1 /DEF=Human SP100-B (SP100-B) mRNA, complete cds. /FEA=mRNA /GEN=SP100-B /PROD=SP100-B /DB_XREF=gi:1173655 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:U36501.1 U36501 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 210219_at U36501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36501.1 /DEF=Human SP100-B (SP100-B) mRNA, complete cds. /FEA=mRNA /GEN=SP100-B /PROD=SP100-B /DB_XREF=gi:1173655 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:U36501.1 U36501 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 210220_at L37882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L37882.1 /DEF=Human frizzled gene product mRNA, complete cds. /FEA=mRNA /GEN=frizzled /DB_XREF=gi:736678 /UG=Hs.81217 frizzled (Drosophila) homolog 2 /FL=gb:AB017364.1 gb:NM_001466.2 gb:L37882.1 L37882 frizzled class receptor 2 FZD2 2535 NM_001466 0001944 // vasculature development // not recorded /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003150 // muscular septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030825 // positive regulation of cGMP metabolic process // inferred from mutant phenotype /// 0030855 // epithelial cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060022 // hard palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 210221_at BC000513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000513.1 /DEF=Homo sapiens, cholinergic receptor, nicotinic, alpha polypeptide 3, clone MGC:8545, mRNA, complete cds. /FEA=mRNA /PROD=cholinergic receptor, nicotinic, alphapolypeptide 3 /DB_XREF=gi:12653482 /UG=Hs.89605 cholinergic receptor, nicotinic, alpha polypeptide 3 /FL=gb:BC000513.1 gb:BC002996.1 gb:BC001642.1 gb:U62432.1 gb:M86383.1 gb:NM_000743.1 BC000513 cholinergic receptor, nicotinic, alpha 3 (neuronal) CHRNA3 1136 NM_000743 /// NM_001166694 /// NR_046313 /// XM_006720382 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060084 // synaptic transmission involved in micturition // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 210222_s_at BC000314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000314.1 /DEF=Homo sapiens, Similar to reticulon 1, clone MGC:8436, mRNA, complete cds. /FEA=mRNA /PROD=Similar to reticulon 1 /DB_XREF=gi:12653096 /UG=Hs.99947 reticulon 1 /FL=gb:BC000314.1 gb:BC003003.1 gb:L10335.1 BC000314 reticulon 1 RTN1 6252 NM_001243115 /// NM_021136 /// NM_206852 /// NM_206857 0007165 // signal transduction // non-traceable author statement /// 0030182 // neuron differentiation // inferred from expression pattern 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210223_s_at AF010446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010446.1 /DEF=Homo sapiens MHC class I related protein 1 isoform B (MR1B) mRNA, complete cds. /FEA=mRNA /GEN=MR1B /PROD=MHC class I related protein 1 isoform B /DB_XREF=gi:4102221 /UG=Hs.101840 major histocompatibility complex, class I-like sequence /FL=gb:AF010446.1 gb:AF031469.1 AF010446 major histocompatibility complex, class I-related MR1 3140 NM_001194999 /// NM_001195000 /// NM_001195035 /// NM_001531 /// XM_005245115 /// XM_006711286 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032620 // interleukin-17 production // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032393 // MHC class I receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 210224_at AF031469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031469.1 /DEF=Homo sapiens MHC class I related protein 1 isoform D (MR1D) mRNA, complete cds. /FEA=mRNA /GEN=MR1D /PROD=MHC class I-related protein 1 isoform D /DB_XREF=gi:4104081 /UG=Hs.101840 major histocompatibility complex, class I-like sequence /FL=gb:AF010446.1 gb:AF031469.1 AF031469 major histocompatibility complex, class I-related MR1 3140 NM_001194999 /// NM_001195000 /// NM_001195035 /// NM_001531 /// XM_005245115 /// XM_006711286 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032620 // interleukin-17 production // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032393 // MHC class I receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 210225_x_at AF009635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009635.1 /DEF=Homo sapiens clone 17.7 immunoglobulin-like transcript 5 protein mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 5 protein /DB_XREF=gi:2662429 /UG=Hs.105928 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 /FL=gb:AF000575.1 gb:U91928.1 gb:AF025533.1 gb:AF009632.1 gb:AF009633.1 gb:AF009635.1 gb:AF009638.1 gb:AF009639.1 gb:AF009641.1 gb:AF009642.1 gb:AF031553.1 gb:AF031554.1 gb:AF031555.1 gb:AF031556.1 gb:NM_006864.1 AF009635 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 LILRB3 11025 NM_001081450 /// NM_006864 /// XM_006722983 /// XM_006722984 /// XM_006722985 /// XM_006726175 /// XM_006726176 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210226_at D85245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D85245.1 /DEF=Homo sapiens mRNA for TR3beta, complete cds. /FEA=mRNA /PROD=TR3beta /DB_XREF=gi:1339917 /UG=Hs.1119 nuclear receptor subfamily 4, group A, member 1 /FL=gb:D85245.1 D85245 nuclear receptor subfamily 4, group A, member 1 NR4A1 3164 NM_001202233 /// NM_001202234 /// NM_002135 /// NM_173157 /// NM_173158 /// XM_005268822 /// XM_005268823 /// XM_005268824 /// XM_006719363 /// XM_006719364 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210227_at AF119817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119817.1 /DEF=Homo sapiens discs, large (Drosophila) homolog-associated protein 2 (DLGAP2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=DLGAP2 /PROD=discs, large (Drosophila) homolog-associatedprotein 2 /DB_XREF=gi:6979172 /UG=Hs.113287 discs, large (Drosophila) homolog-associated protein 2 /FL=gb:NM_004745.1 gb:AF119817.1 AF119817 discs, large (Drosophila) homolog-associated protein 2 DLGAP2 9228 NM_001277161 /// NM_004745 /// XM_005266038 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // non-traceable author statement 0005883 // neurofilament // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210228_at M11734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M11734.1 /DEF=Human granulocytemacrophage colony-stimulating factor mRNA, complete cds. /FEA=mRNA /GEN=CSF2 /DB_XREF=gi:181149 /UG=Hs.1349 colony stimulating factor 2 (granulocyte-macrophage) /FL=gb:M11734.1 gb:NM_000758.1 M11734 colony stimulating factor 2 (granulocyte-macrophage) CSF2 1437 NM_000758 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045918 // negative regulation of cytolysis // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071803 // positive regulation of podosome assembly // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005129 // granulocyte macrophage colony-stimulating factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 210229_s_at M11734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M11734.1 /DEF=Human granulocytemacrophage colony-stimulating factor mRNA, complete cds. /FEA=mRNA /GEN=CSF2 /DB_XREF=gi:181149 /UG=Hs.1349 colony stimulating factor 2 (granulocyte-macrophage) /FL=gb:M11734.1 gb:NM_000758.1 M11734 colony stimulating factor 2 (granulocyte-macrophage) CSF2 1437 NM_000758 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045918 // negative regulation of cytolysis // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071803 // positive regulation of podosome assembly // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005129 // granulocyte macrophage colony-stimulating factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 210230_at BC003629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003629.1 /DEF=Homo sapiens, clone MGC:2854, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2854) /DB_XREF=gi:13177696 /UG=Hs.136075 Homo sapiens cDNA: FLJ23438 fis, clone HRC13275 /FL=gb:BC003629.1 BC003629 210231_x_at D45198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D45198.1 /DEF=Human mRNA for template acyivating factor-I alpha, complete cds. /FEA=mRNA /GEN=set /PROD=template acyivating factor-I alpha /DB_XREF=gi:971271 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:D45198.1 D45198 SET nuclear proto-oncogene SET 6418 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 210232_at M35543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M35543.1 /DEF=Human GTP-binding protein (G25K) mRNA, complete cds. /FEA=mRNA /GEN=CDC42 /DB_XREF=gi:182856 /UG=Hs.146409 cell division cycle 42 (GTP-binding protein, 25kD) /FL=gb:M35543.1 M35543 cell division cycle 42 CDC42 998 NM_001039802 /// NM_001791 /// NM_044472 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from physical interaction /// 0031424 // keratinization // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048554 // positive regulation of metalloenzyme activity // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0051647 // nucleus localization // inferred from electronic annotation /// 0051683 // establishment of Golgi localization // inferred from sequence or structural similarity /// 0051835 // positive regulation of synapse structural plasticity // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060661 // submandibular salivary gland formation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0071338 // positive regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0072384 // organelle transport along microtubule // inferred from sequence or structural similarity /// 0090135 // actin filament branching // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 210233_at AF167343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF167343.1 /DEF=Homo sapiens soluble interleukin-1 receptor accessory protein (IL1RAP) mRNA, complete cds. /FEA=mRNA /GEN=IL1RAP /PROD=soluble interleukin-1 receptor accessoryprotein /DB_XREF=gi:8050486 /UG=Hs.173880 interleukin 1 receptor accessory protein /FL=gb:AF167343.1 AF167343 interleukin 1 receptor accessory protein IL1RAP 3556 NM_001167928 /// NM_001167929 /// NM_001167930 /// NM_001167931 /// NM_002182 /// NM_134470 /// XM_005247433 /// XM_005247434 0006461 // protein complex assembly // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210234_at U92457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U92457.1 /DEF=Human metabotropic glutamate receptor 4 mRNA, complete cds. /FEA=mRNA /PROD=metabotropic glutamate receptor 4 /DB_XREF=gi:1935038 /UG=Hs.178078 glutamate receptor, metabotropic 4 /FL=gb:U92457.1 gb:NM_000841.1 U92457 glutamate receptor, metabotropic 4 GRM4 2914 NM_000841 /// NM_001256809 /// NM_001256810 /// NM_001256811 /// NM_001256812 /// NM_001256813 /// NM_001256814 /// NM_001282847 /// XM_006715071 /// XR_427829 0000187 // activation of MAPK activity // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from expression pattern /// 0043523 // regulation of neuron apoptotic process // traceable author statement /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042734 // presynaptic membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0048787 // presynaptic active zone membrane // inferred from electronic annotation 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // inferred from mutant phenotype /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation 210235_s_at U22815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U22815.1 /DEF=Human LAR-interacting protein 1a mRNA, complete cds. /FEA=mRNA /PROD=LAR-interacting protein 1a /DB_XREF=gi:930340 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:U22815.1 U22815 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210236_at U22815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U22815.1 /DEF=Human LAR-interacting protein 1a mRNA, complete cds. /FEA=mRNA /PROD=LAR-interacting protein 1a /DB_XREF=gi:930340 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:U22815.1 U22815 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210237_at AF120274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF120274.1 /DEF=Homo sapiens pre-pro-neublastin mRNA, complete cds. /FEA=mRNA /PROD=pre-pro-neublastin /DB_XREF=gi:4455084 /UG=Hs.194689 artemin /FL=gb:AF120274.1 AF120274 artemin ARTN 9048 NM_001136215 /// NM_003976 /// NM_057090 /// NM_057091 /// NM_057160 /// XM_006711023 /// XM_006711024 0007165 // signal transduction // traceable author statement /// 0007405 // neuroblast proliferation // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0097021 // lymphocyte migration into lymphoid organs // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 210239_at U90304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90304.1 /DEF=Human iroquois-class homeodomain protein IRX-2a mRNA, complete cds. /FEA=mRNA /PROD=iroquois-class homeodomain protein IRX-2a /DB_XREF=gi:1899219 /UG=Hs.25351 iroquois homeobox protein 5 /FL=gb:U90304.1 gb:NM_005853.1 U90304 iroquois homeobox 5 IRX5 10265 NM_001252197 /// NM_005853 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008406 // gonad development // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060040 // retinal bipolar neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005499 // vitamin D binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210240_s_at U20498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20498.1 /DEF=Human p19 protein mRNA, complete cds. /FEA=mRNA /PROD=p19 protein /DB_XREF=gi:1161921 /UG=Hs.29656 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) /FL=gb:U40343.1 gb:U20498.1 gb:BC001822.1 gb:U49399.1 gb:NM_001800.1 U20498 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) CDKN2D 1032 NM_001800 /// NM_079421 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0033280 // response to vitamin D // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 210241_s_at AB007458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007458.1 /DEF=Homo sapiens mRNA for P53TG1-D, complete cds. /FEA=mRNA /GEN=P53TG1 /PROD=P53TG1-D /DB_XREF=gi:5006272 /UG=Hs.306301 Homo sapiens mRNA for P53TG1-D, complete cds /FL=gb:AB007458.1 AB007458 TP53 target 1 (non-protein coding) TP53TG1 11257 NM_007233 /// NR_015381 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement 210242_x_at AF249277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF249277.1 /DEF=Homo sapiens cervical cancer suppressor-1 mRNA, complete cds. /FEA=mRNA /PROD=cervical cancer suppressor-1 /DB_XREF=gi:10442005 /UG=Hs.314544 Homo sapiens cervical cancer suppressor-1 mRNA, complete cds /FL=gb:AF249277.1 AF249277 suppressor of tumorigenicity 20 ST20 400410 NM_001100879 /// NM_001100880 /// NM_001199757 /// NR_037652 /// NR_037653 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005741 // mitochondrial outer membrane // not recorded 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded 210243_s_at AF038661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF038661.1 /DEF=Homo sapiens chromosome 1q21-1q23 beta-1,4-galactosyltransferase mRNA, complete cds. /FEA=mRNA /PROD=beta-1,4-galactosyltransferase /DB_XREF=gi:3132897 /UG=Hs.321231 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 /FL=gb:AF038661.1 AF038661 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 B4GALT3 8703 NM_001199873 /// NM_001199874 /// NM_003779 /// XM_005245566 /// XM_006711600 /// XM_006711601 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0003945 // N-acetyllactosamine synthase activity // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210244_at U19970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19970.1 /DEF=Human antimicrobial LPS-binding protein CAP18 precursor mRNA, complete cds. /FEA=mRNA /PROD=CAP18 precursor /DB_XREF=gi:643476 /UG=Hs.51120 cathelicidin antimicrobial peptide /FL=gb:NM_004345.1 gb:U19970.1 U19970 cathelicidin antimicrobial peptide CAMP 820 NM_004345 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044140 // negative regulation of growth of symbiont on or near host surface // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0051701 // interaction with host // traceable author statement /// 0051873 // killing by host of symbiont cells // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071354 // cellular response to interleukin-6 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005618 // cell wall // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042581 // specific granule // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210245_at L78207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L78207.1 /DEF=Homo sapiens sulfonylurea receptor (SUR1) mRNA, complete cds. /FEA=mRNA /GEN=SUR1 /PROD=sulfonylurea receptor /DB_XREF=gi:1374674 /UG=Hs.54470 ATP-binding cassette, sub-family C (CFTRMRP), member 8 /FL=gb:L78207.1 gb:U63421.1 gb:AF087138.1 gb:NM_000352.2 L78207 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 ABCC8 6833 NM_000352 /// NM_001287174 /// XM_006718286 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008281 // sulfonylurea receptor activity // inferred from electronic annotation /// 0015079 // potassium ion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 210246_s_at AF087138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF087138.1 /DEF=Homo sapiens sulfonylurea receptor 1 (SUR1) mRNA, complete cds. /FEA=mRNA /GEN=SUR1 /PROD=sulfonylurea receptor 1 /DB_XREF=gi:3643189 /UG=Hs.54470 ATP-binding cassette, sub-family C (CFTRMRP), member 8 /FL=gb:L78207.1 gb:U63421.1 gb:AF087138.1 gb:NM_000352.2 AF087138 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 ABCC8 6833 NM_000352 /// NM_001287174 /// XM_006718286 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008281 // sulfonylurea receptor activity // inferred from electronic annotation /// 0015079 // potassium ion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 210247_at AW139618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139618 /FEA=EST /DB_XREF=gi:6144336 /DB_XREF=est:UI-H-BI1-aea-h-11-0-UI.s1 /CLONE=IMAGE:2718956 /UG=Hs.6439 synapsin II /FL=gb:AF077671.1 AW139618 synapsin II SYN2 6854 NM_003178 /// NM_133625 /// XM_006713311 /// XM_006713312 /// XM_006713313 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 210248_at D83175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83175.1 /DEF=Homo sapiens WNT7a mRNA, complete cds. /FEA=mRNA /GEN=WNT7a /DB_XREF=gi:5509900 /UG=Hs.72290 wingless-type MMTV integration site family, member 7A /FL=gb:U53476.1 gb:NM_004625.1 gb:D83175.1 D83175 wingless-type MMTV integration site family, member 7A WNT7A 7476 NM_004625 0000578 // embryonic axis specification // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0008105 // asymmetric protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0014719 // satellite cell activation // inferred from electronic annotation /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0031133 // regulation of axon diameter // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035116 // embryonic hindlimb morphogenesis // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0035659 // Wnt signaling pathway involved in wound healing, spreading of epidermal cells // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // not recorded /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0048864 // stem cell development // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from direct assay /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from direct assay /// 0060021 // palate development // inferred from mutant phenotype /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060066 // oviduct development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060173 // limb development // inferred from electronic annotation /// 0061038 // uterus morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // not recorded /// 0005125 // cytokine activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred by curator /// 0048018 // receptor agonist activity // inferred from direct assay 210249_s_at U59302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59302.1 /DEF=Human steroid receptor coactivator-1 F-SRC-1 mRNA, complete cds. /FEA=mRNA /PROD=steroid receptor coactivator-1 F-SRC-1 /DB_XREF=gi:1480645 /UG=Hs.74002 nuclear receptor coactivator 1 /FL=gb:U40396.1 gb:U59302.1 gb:U90661.1 gb:NM_003743.1 U59302 nuclear receptor coactivator 1 NCOA1 8648 NM_003743 /// NM_147223 /// NM_147233 /// XM_005264625 /// XM_005264626 /// XM_005264627 /// XM_005264628 /// XM_006712126 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000435 // positive regulation of transcription from RNA polymerase II promoter by galactose // inferred from direct assay /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 2001038 // regulation of cellular response to drug // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033142 // progesterone receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0071837 // HMG box domain binding // inferred from electronic annotation 210250_x_at AF067854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067854.1 /DEF=Homo sapiens adenylosuccinate lyase (ADSL) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=ADSL /PROD=adenylosuccinate lyase /DB_XREF=gi:3211983 /UG=Hs.75527 adenylosuccinate lyase /FL=gb:AF067854.1 AF067854 adenylosuccinate lyase ADSL 158 NM_000026 /// NM_001123378 0001666 // response to hypoxia // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006163 // purine nucleotide metabolic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred by curator /// 0006167 // AMP biosynthetic process // inferred from direct assay /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009152 // purine ribonucleotide biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044208 // 'de novo' AMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // inferred from direct assay /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0070626 // (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity // inferred from electronic annotation 210251_s_at AF112221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112221.1 /DEF=Homo sapiens rap2 interacting protein x mRNA, complete cds. /FEA=mRNA /PROD=rap2 interacting protein x /DB_XREF=gi:6563227 /UG=Hs.7972 KIAA0871 protein /FL=gb:AF112221.1 AF112221 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210252_s_at AB002356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002356.1 /DEF=Human mRNA for KIAA0358 gene, complete cds. /FEA=mRNA /GEN=KIAA0358 /DB_XREF=gi:2224656 /UG=Hs.82548 MAP-kinase activating death domain /FL=gb:AB002356.1 AB002356 MAP-kinase activating death domain MADD 8567 NM_001135943 /// NM_001135944 /// NM_003682 /// NM_130470 /// NM_130471 /// NM_130472 /// NM_130473 /// NM_130474 /// NM_130475 /// NM_130476 /// XM_005253188 /// XM_005253189 /// XM_005253190 /// XM_005253191 /// XM_005253192 /// XM_005253193 /// XM_005253194 /// XM_005253195 /// XM_005253196 /// XM_005253197 /// XM_005253198 /// XM_005253199 /// XM_005253200 /// XM_005253201 /// XM_005253202 /// XM_005253203 /// XM_005253204 /// XM_005253205 /// XM_005253206 /// XM_006718360 /// XM_006718361 /// XM_006718362 /// XM_006718363 /// XR_242830 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032483 // regulation of Rab protein signal transduction // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0030295 // protein kinase activator activity // traceable author statement 210253_at AF092095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF092095.1 /DEF=Homo sapiens alternatively spliced product of metastasis-suppressor gene CC3 (TC3) mRNA, complete cds. /FEA=mRNA /GEN=TC3 /PROD=alternatively spliced product ofmetastasis-suppressor gene CC3 /DB_XREF=gi:3892222 /UG=Hs.90753 Tat-interacting protein (30kD) /FL=gb:AF092095.1 AF092095 HIV-1 Tat interactive protein 2, 30kDa HTATIP2 10553 NM_001098520 /// NM_001098521 /// NM_001098522 /// NM_001098523 /// NM_006410 0001525 // angiogenesis // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation 210254_at L35848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L35848.1 /DEF=Homo sapiens IgE receptor beta chain (HTm4) mRNA, complete cds. /FEA=mRNA /GEN=HTm4 /PROD=IgE receptor beta subunit /DB_XREF=gi:561638 /UG=Hs.99960 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) /FL=gb:NM_006138.1 gb:L35848.1 L35848 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) MS4A3 932 NM_001031666 /// NM_001031809 /// NM_006138 0005737 // cytoplasm // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210255_at U84138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84138.1 /DEF=Homo sapiens DNA repair protein RAD51B mRNA, complete cds. /FEA=mRNA /PROD=DNA repair protein RAD51B /DB_XREF=gi:2801404 /UG=Hs.100669 RAD51 (S. cerevisiae)-like 1 /FL=gb:NM_002877.1 gb:U92074.1 gb:U84138.1 U84138 RAD51 paralog B RAD51B 5890 NM_002877 /// NM_133509 /// NM_133510 /// XM_005267961 /// XM_005267962 /// XM_005267963 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 210256_s_at U78576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78576.1 /DEF=Human 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha mRNA, clone PIP5KIa2, complete cds. /FEA=mRNA /PROD=68 kDa type I phosphatidylinositol-4-phosphate5-kinase alpha /DB_XREF=gi:1743872 /UG=Hs.149255 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha /FL=gb:U78576.1 U78576 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha PIP5K1A 8394 NM_001135636 /// NM_001135637 /// NM_001135638 /// NM_003557 /// XM_005245525 /// XM_005245526 /// XM_005245527 /// XM_005245528 /// XM_005245529 /// XM_005245530 /// XM_005245531 /// XM_005245532 /// XM_006711563 /// XM_006711564 /// XM_006711565 /// XM_006711566 /// XM_006711567 /// XM_006711568 0006644 // phospholipid metabolic process // traceable author statement /// 0006650 // glycerophospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006909 // phagocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from direct assay /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement /// 0030216 // keratinocyte differentiation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0097178 // ruffle assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay 210257_x_at AF212995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF212995.1 /DEF=Homo sapiens cullin CUL4B (CUL4B) mRNA, complete cds. /FEA=mRNA /GEN=CUL4B /PROD=cullin CUL4B /DB_XREF=gi:13259126 /UG=Hs.155976 cullin 4B /FL=gb:AF212995.1 AF212995 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 210258_at AF030107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF030107.1 /DEF=Homo sapiens regulator of G protein signaling (RGS13) mRNA, complete cds. /FEA=mRNA /GEN=RGS13 /PROD=RGS13 /DB_XREF=gi:2598184 /UG=Hs.17165 regulator of G-protein signalling 13 /FL=gb:AF030107.1 AF030107 regulator of G-protein signaling 13 RGS13 6003 NM_002927 /// NM_144766 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 210259_s_at AF254115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF254115.1 /DEF=Homo sapiens beta protein 1 BP1 mRNA, complete cds. /FEA=mRNA /PROD=beta protein 1 BP1 /DB_XREF=gi:11141506 /UG=Hs.172648 distal-less homeobox 4 /FL=gb:AF254115.1 AF254115 distal-less homeobox 4 DLX4 1748 NM_001934 /// NM_138281 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 210260_s_at BC005352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005352.1 /DEF=Homo sapiens, TNF-induced protein, clone MGC:12451, mRNA, complete cds. /FEA=mRNA /PROD=TNF-induced protein /DB_XREF=gi:13529163 /UG=Hs.17839 TNF-induced protein /FL=gb:BC005352.1 gb:AF099935.1 BC005352 tumor necrosis factor, alpha-induced protein 8 TNFAIP8 25816 NM_001077654 /// NM_001286813 /// NM_001286814 /// NM_001286815 /// NM_001286817 /// NM_014350 /// XM_006714584 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype 210261_at AF004711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004711.1 /DEF=Homo sapiens two-pore potassium channel TPKC1 mRNA, complete cds. /FEA=mRNA /PROD=two-pore potassium channel TPKC1 /DB_XREF=gi:4101565 /UG=Hs.202696 potassium channel, subfamily K, member 2 (TREK-1) /FL=gb:AF004711.1 gb:AF129399.1 gb:AF171068.1 AF004711 potassium channel, subfamily K, member 2 KCNK2 3776 NM_001017424 /// NM_001017425 /// NM_014217 /// XM_006711307 /// XR_247027 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015271 // outward rectifier potassium channel activity // inferred from sequence or structural similarity /// 0019870 // potassium channel inhibitor activity // inferred from sequence or structural similarity /// 0022841 // potassium ion leak channel activity // inferred from sequence or structural similarity 210262_at M25532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25532.1 /DEF=Human testis-specific protein (Tpx-1) mRNA, complete cds. /FEA=mRNA /GEN=GAPDL5 /DB_XREF=gi:339882 /UG=Hs.2042 testis specific protein 1 (probe H4-1 p3-1) /FL=gb:M25532.1 gb:NM_003296.1 M25532 cysteine-rich secretory protein 2 CRISP2 7180 NM_001142407 /// NM_001142408 /// NM_001142417 /// NM_001142435 /// NM_001261822 /// NM_003296 /// XM_005249349 /// XM_005249350 /// XM_005249351 /// XM_005249352 /// XM_005249353 /// XM_005249354 /// XM_005249356 /// XM_005249357 /// XM_005249358 /// XR_241914 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 210263_at AF029780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF029780.1 /DEF=Homo sapiens potassium channel mRNA, complete cds. /FEA=mRNA /PROD=potassium channel /DB_XREF=gi:12001823 /UG=Hs.23735 potassium voltage-gated channel, subfamily F, member 1 /FL=gb:AF029780.1 gb:AF033382.1 gb:NM_002236.1 AF029780 potassium voltage-gated channel, subfamily F, member 1 KCNF1 3754 NM_002236 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement 210264_at AF089087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF089087.1 /DEF=Homo sapiens G protein-coupled receptor mRNA, complete cds. /FEA=mRNA /PROD=G protein-coupled receptor /DB_XREF=gi:10503932 /UG=Hs.239891 G protein-coupled receptor 35 /FL=gb:AF089087.1 gb:NM_005301.1 AF089087 G protein-coupled receptor 35 GPR35 2859 NM_001195381 /// NM_001195382 /// NM_005301 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay 210265_x_at AF268617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF268617.1 /DEF=Homo sapiens POU 5 domain protein (POU5FLC12) mRNA, complete cds. /FEA=mRNA /GEN=POU5FLC12 /PROD=POU 5 domain protein /DB_XREF=gi:12382251 /UG=Hs.2860 POU domain, class 5, transcription factor 1 /FL=gb:AF268617.1 AF268617 POU class 5 homeobox 1 pseudogene 3 POU5F1P3 642559 NR_036440 0001714 // endodermal cell fate specification // inferred from direct assay /// 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0003130 // BMP signaling pathway involved in heart induction // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009786 // regulation of asymmetric cell division // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from direct assay /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060795 // cell fate commitment involved in formation of primary germ layer // inferred from mutant phenotype /// 0060913 // cardiac cell fate determination // inferred from direct assay /// 0060965 // negative regulation of gene silencing by miRNA // inferred from mutant phenotype /// 0090081 // regulation of heart induction by regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090308 // regulation of methylation-dependent chromatin silencing // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 210266_s_at AF220137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220137.1 /DEF=Homo sapiens tripartite motif protein TRIM33 beta mRNA, complete cds; alternatively spliced. /FEA=mRNA /PROD=tripartite motif protein TRIM33 beta /DB_XREF=gi:12407442 /UG=Hs.287414 transcriptional intermediary factor 1 gamma /FL=gb:AF220137.1 AF220137 tripartite motif containing 33 TRIM33 51592 NM_015906 /// NM_033020 /// XM_005270936 /// XM_005270937 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 210267_at BC001265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001265.1 /DEF=Homo sapiens, Similar to hypothetical protein dJ462O23.2, clone MGC:5034, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein dJ462O23.2 /DB_XREF=gi:12654842 /UG=Hs.307035 Homo sapiens, Similar to hypothetical protein dJ462O23.2, clone MGC:5034, mRNA, complete cds /FL=gb:BC001265.1 BC001265 NIPA-like domain containing 3 NIPAL3 57185 NM_020448 /// XM_005245947 /// XM_005245948 /// XM_006710780 0015693 // magnesium ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 210268_at AF332009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332009.1 /DEF=Homo sapiens nuclear transcription factor NFX2 (NFX2) mRNA, complete cds. /FEA=mRNA /GEN=NFX2 /PROD=nuclear transcription factor NFX2 /DB_XREF=gi:13242068 /UG=Hs.3187 nuclear transcription factor, X-box binding 1 /FL=gb:AF332009.1 AF332009 nuclear transcription factor, X-box binding 1 NFX1 4799 NM_002504 /// NM_147133 /// NM_147134 /// XM_005251473 /// XM_005251474 /// XM_005251475 /// XM_006716776 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210269_s_at M99578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M99578.1 /DEF=Human lymphocyte surface protein exons 1-5, complete cds. /FEA=mRNA /DB_XREF=gi:187241 /UG=Hs.321160 Human lymphocyte surface protein exons 1-5, complete cds /FL=gb:M99578.1 M99578 A kinase (PRKA) anchor protein 17A AKAP17A 8227 NM_005088 /// NR_027383 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042113 // B cell activation // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 2000019 // negative regulation of male gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from direct assay /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 210270_at AF156932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF156932.1 /DEF=Homo sapiens G protein signaling 6 regulator (RGS6) mRNA, complete cds. /FEA=mRNA /GEN=RGS6 /PROD=G protein signaling 6 regulator /DB_XREF=gi:5107938 /UG=Hs.3221 regulator of G-protein signalling 6 /FL=gb:AF073920.1 gb:NM_004296.1 gb:AF107620.1 gb:AF156932.1 AF156932 regulator of G-protein signaling 6 RGS6 9628 NM_001204416 /// NM_001204417 /// NM_001204418 /// NM_001204419 /// NM_001204420 /// NM_001204421 /// NM_001204422 /// NM_001204423 /// NM_001204424 /// NM_004296 /// XM_005268234 /// XM_005268235 /// XM_005268236 /// XM_006720327 /// XM_006720328 /// XM_006720329 /// XM_006720330 /// XM_006720331 /// XM_006720332 /// XM_006720333 /// XR_429335 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 210271_at AB021742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB021742.1 /DEF=Homo sapiens NDRF gene for neuroD-related factor, complete cds. /FEA=mRNA /GEN=NDRF /PROD=neuroD-related factor /DB_XREF=gi:4808463 /UG=Hs.322431 neurogenic differentiation 2 /FL=gb:AB021742.1 gb:NM_006160.1 AB021742 neuronal differentiation 2 NEUROD2 4761 NM_006160 /// XM_005257409 0001662 // behavioral fear response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008306 // associative learning // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0021695 // cerebellar cortex development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031915 // positive regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0071257 // cellular response to electrical stimulus // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2000297 // negative regulation of synapse maturation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 210272_at M29873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29873.1 /DEF=Human cytochrome P450-IIB (hIIB3) mRNA, complete cds. /FEA=mRNA /GEN=CYP2B /DB_XREF=gi:181293 /UG=Hs.330780 Human cytochrome P450-IIB (hIIB3) mRNA, complete cds /FL=gb:M29873.1 M29873 cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene CYP2B7P 1556 NR_001278 0055114 // oxidation-reduction process // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210273_at AB006757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006757.1 /DEF=Homo sapiens mRNA for PCDH7 (BH-Pcdh)c, complete cds. /FEA=mRNA /PROD=PCDH7 (BH-Pcdh)c /DB_XREF=gi:2979421 /UG=Hs.34073 BH-protocadherin (brain-heart) /FL=gb:AB006757.1 AB006757 protocadherin 7 PCDH7 5099 NM_001173523 /// NM_002589 /// NM_032456 /// NM_032457 /// XM_005248163 /// XM_005248164 /// XM_005248165 /// XM_005248166 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 210274_at BC002455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002455.1 /DEF=Homo sapiens, melanoma antigen, family A, 8, clone MGC:2182, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 8 /DB_XREF=gi:12803278 /UG=Hs.37109 melanoma antigen, family A, 8 /FL=gb:BC002455.1 gb:NM_005364.1 BC002455 melanoma antigen family A, 8 MAGEA8 4107 NM_001166400 /// NM_001166401 /// NM_005364 210275_s_at AF062347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062347.1 /DEF=Homo sapiens zinc finger protein 216 splice variant 2 (ZNF216) mRNA, complete cds. /FEA=mRNA /GEN=ZNF216 /PROD=zinc finger protein 216 splice variant 2 /DB_XREF=gi:3643810 /UG=Hs.3776 zinc finger protein 216 /FL=gb:AF062347.1 AF062347 zinc finger, AN1-type domain 5 ZFAND5 7763 NM_001102420 /// NM_001102421 /// NM_001278243 /// NM_001278244 /// NM_001278245 /// NM_006007 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210276_s_at AF281030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF281030.1 /DEF=Homo sapiens Tara mRNA, complete cds. /FEA=mRNA /PROD=Tara /DB_XREF=gi:12006357 /UG=Hs.40342 putative nuclear protein /FL=gb:AF281030.1 gb:BC003618.1 AF281030 nucleolar protein 12 /// TRIO and F-actin binding protein NOL12 /// TRIOBP 11078 /// 79159 NM_001039141 /// NM_007032 /// NM_024313 /// NM_138632 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030047 // actin modification // non-traceable author statement /// 0051016 // barbed-end actin filament capping // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0030496 // midbody // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045159 // myosin II binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from direct assay 210277_at AF155159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155159.1 /DEF=Homo sapiens adaptor-related protein complex AP-4 sigma4 subunit mRNA, complete cds. /FEA=mRNA /PROD=adaptor-related protein complex AP-4 sigma4subunit /DB_XREF=gi:5442367 /UG=Hs.50628 adaptor-related protein complex 4, sigma 1 subunit /FL=gb:AF155159.1 gb:AB030654.1 gb:NM_007077.1 AF155159 adaptor-related protein complex 4, sigma 1 subunit AP4S1 11154 NM_001128126 /// NM_001254726 /// NM_001254727 /// NM_001254728 /// NM_001254729 /// NM_007077 /// XM_005267293 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 210278_s_at AF155159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155159.1 /DEF=Homo sapiens adaptor-related protein complex AP-4 sigma4 subunit mRNA, complete cds. /FEA=mRNA /PROD=adaptor-related protein complex AP-4 sigma4subunit /DB_XREF=gi:5442367 /UG=Hs.50628 adaptor-related protein complex 4, sigma 1 subunit /FL=gb:AF155159.1 gb:AB030654.1 gb:NM_007077.1 AF155159 adaptor-related protein complex 4, sigma 1 subunit AP4S1 11154 NM_001128126 /// NM_001254726 /// NM_001254727 /// NM_001254728 /// NM_001254729 /// NM_007077 /// XM_005267293 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 210279_at AF261135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF261135.1 /DEF=Homo sapiens GPR18-iso mRNA, complete cds. /FEA=mRNA /PROD=GPR18-iso /DB_XREF=gi:12005919 /UG=Hs.88269 Homo sapiens clone IMAGE:1837189, mRNA sequence /FL=gb:AF261135.1 AF261135 G protein-coupled receptor 18 GPR18 2841 NM_001098200 /// NM_005292 /// XM_006719946 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement 210280_at D10537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D10537.1 /DEF=Homo sapiens mRNA for major structural protein of myelin, complete cds. /FEA=mRNA /PROD=major structural protein of myelin /DB_XREF=gi:220073 /UG=Hs.93883 myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) /FL=gb:D10537.1 gb:NM_000530.1 D10537 myelin protein zero MPZ 4359 NM_000530 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0045217 // cell-cell junction maintenance // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210281_s_at AL136621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136621.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B162 (from clone DKFZp564B162); complete cds. /FEA=mRNA /GEN=DKFZp564B162 /PROD=hypothetical protein /DB_XREF=gi:12052767 /UG=Hs.109526 zinc finger protein 198 /FL=gb:AL136621.1 AL136621 zinc finger, MYM-type 2 ZMYM2 7750 NM_001190964 /// NM_001190965 /// NM_003453 /// NM_197968 /// XM_005266517 /// XM_005266518 /// XM_005266519 /// XM_005266520 /// XM_005266521 /// XM_006719864 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0008270 // zinc ion binding // non-traceable author statement /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210282_at AL136621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136621.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B162 (from clone DKFZp564B162); complete cds. /FEA=mRNA /GEN=DKFZp564B162 /PROD=hypothetical protein /DB_XREF=gi:12052767 /UG=Hs.109526 zinc finger protein 198 /FL=gb:AL136621.1 AL136621 zinc finger, MYM-type 2 ZMYM2 7750 NM_001190964 /// NM_001190965 /// NM_003453 /// NM_197968 /// XM_005266517 /// XM_005266518 /// XM_005266519 /// XM_005266520 /// XM_005266521 /// XM_006719864 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0008270 // zinc ion binding // non-traceable author statement /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210283_x_at BC005295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005295.1 /DEF=Homo sapiens, Similar to polyadenylate binding protein-interacting protein 1, clone MGC:12360, mRNA, complete cds. /FEA=mRNA /PROD=Similar to polyadenylate bindingprotein-interacting protein 1 /DB_XREF=gi:13529010 /UG=Hs.109643 polyadenylate binding protein-interacting protein 1 /FL=gb:BC005295.1 BC005295 poly(A) binding protein interacting protein 1 PAIP1 10605 NM_006451 /// NM_182789 /// NM_183323 /// XM_005248230 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 210284_s_at AF241230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241230.1 /DEF=Homo sapiens TAK1-binding protein 2 mRNA, complete cds. /FEA=mRNA /PROD=TAK1-binding protein 2 /DB_XREF=gi:7677465 /UG=Hs.109727 TAK1-binding protein 2; KIAA0733 protein /FL=gb:AF241230.1 AF241230 TGF-beta activated kinase 1/MAP3K7 binding protein 2 TAB2 23118 NM_001292034 /// NM_001292035 /// NM_015093 /// NM_145342 /// XM_006715403 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from direct assay 210285_x_at BC000383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000383.1 /DEF=Homo sapiens, Wilms tumour 1-associating protein, clone MGC:8419, mRNA, complete cds. /FEA=mRNA /PROD=Wilms tumour 1-associating protein /DB_XREF=gi:12653228 /UG=Hs.119 Wilms tumour 1-associating protein /FL=gb:BC000383.1 gb:BC004432.1 BC000383 Wilms tumor 1 associated protein WTAP 9589 NM_001270531 /// NM_001270532 /// NM_001270533 /// NM_004906 /// NM_152857 /// NM_152858 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0080009 // mRNA methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 210286_s_at AF053755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053755.1 /DEF=Homo sapiens bicarbonate transporter (BT) mRNA, complete cds. /FEA=mRNA /GEN=BT /PROD=bicarbonate transporter /DB_XREF=gi:6650103 /UG=Hs.132904 solute carrier family 4, sodium bicarbonate cotransporter, member 7 /FL=gb:AF053755.1 AF053755 solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 9497 NM_001258379 /// NM_001258380 /// NM_003615 /// XM_005265598 /// XM_005265599 /// XM_005265600 /// XM_005265601 /// XM_006713421 /// XR_245166 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 210287_s_at U01134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01134.1 /DEF=Human soluble vascular endothelial cell growth factor receptor (sflt) mRNA, complete cds. /FEA=mRNA /GEN=sflt /PROD=soluble vascular endothelial cell growth factorreceptor /DB_XREF=gi:451321 /UG=Hs.138671 fms-related tyrosine kinase 1 (vascular endothelial growth factorvascular permeability factor receptor) /FL=gb:U01134.1 U01134 fms-related tyrosine kinase 1 FLT1 2321 NM_001159920 /// NM_001160030 /// NM_001160031 /// NM_002019 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036323 // vascular endothelial growth factor receptor-1 signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048598 // embryonic morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0036326 // VEGF-A-activated receptor activity // inferred from direct assay /// 0036327 // VEGF-B-activated receptor activity // inferred from direct assay /// 0036332 // placental growth factor-activated receptor activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation 210288_at AF081675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081675.1 /DEF=Homo sapiens ITIM-containing receptor MAFA-L mRNA, complete cds. /FEA=mRNA /PROD=ITIM-containing receptor MAFA-L /DB_XREF=gi:3421400 /UG=Hs.146322 killer cell lectin-like receptor subfamily G, member 1 /FL=gb:AF034952.1 gb:AF081675.1 gb:AF097358.1 gb:NM_005810.1 AF081675 killer cell lectin-like receptor subfamily G, member 1 KLRG1 10219 NM_005810 /// XM_006719026 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 210289_at AB013094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013094.1 /DEF=Homo sapiens TSC501 mRNA, complete cds. /FEA=mRNA /GEN=TSC501 /DB_XREF=gi:3721765 /UG=Hs.14637 kidney- and liver-specific gene /FL=gb:AB013094.1 gb:AB019551.1 gb:AF187813.1 AB013094 N-acetyltransferase 8 (GCN5-related, putative) /// N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) NAT8 /// NAT8B 9027 /// 51471 NM_003960 /// NM_016347 0001702 // gastrulation with mouth forming second // inferred from mutant phenotype /// 0001702 // gastrulation with mouth forming second // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008080 // N-acetyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 210290_at BC001161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001161.1 /DEF=Homo sapiens, Similar to zinc finger protein 174, clone MGC:1578, mRNA, complete cds. /FEA=mRNA /PROD=Similar to zinc finger protein 174 /DB_XREF=gi:12654646 /UG=Hs.155204 zinc finger protein 174 /FL=gb:BC000876.1 gb:BC001161.1 BC001161 zinc finger protein 174 ZNF174 7727 NM_001032292 /// NM_003450 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210291_s_at BC001161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001161.1 /DEF=Homo sapiens, Similar to zinc finger protein 174, clone MGC:1578, mRNA, complete cds. /FEA=mRNA /PROD=Similar to zinc finger protein 174 /DB_XREF=gi:12654646 /UG=Hs.155204 zinc finger protein 174 /FL=gb:BC000876.1 gb:BC001161.1 BC001161 zinc finger protein 174 ZNF174 7727 NM_001032292 /// NM_003450 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210292_s_at AF332218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332218.1 /DEF=Homo sapiens chromosome X protocadherin 11 (PCDH11) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=PCDH11 /PROD=protocadherin 11 /DB_XREF=gi:13161062 /UG=Hs.159156 protocadherin 11 /FL=gb:AF332218.1 AF332218 protocadherin 11 X-linked /// protocadherin 11 Y-linked PCDH11X /// PCDH11Y 27328 /// 83259 NM_001168360 /// NM_001168361 /// NM_001168362 /// NM_001168363 /// NM_001278619 /// NM_014522 /// NM_032967 /// NM_032968 /// NM_032969 /// NM_032971 /// NM_032972 /// NM_032973 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 210293_s_at BC005032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005032.1 /DEF=Homo sapiens, Sec23 (S. cerevisiae) homolog B, clone MGC:12666, mRNA, complete cds. /FEA=mRNA /PROD=Sec23 (S. cerevisiae) homolog B /DB_XREF=gi:13477148 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005032.1 BC005032 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_001172745 /// NM_001172746 /// NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 210294_at AF067286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067286.3 /DEF=Homo sapiens tapasinas (tapasin) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=tapasin /PROD=tapasinas /DB_XREF=gi:10803729 /UG=Hs.179600 TAP binding protein (tapasin) /FL=gb:AF067286.3 AF067286 TAP binding protein (tapasin) TAPBP 6892 NM_003190 /// NM_172208 /// NM_172209 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // non-traceable author statement /// 0006955 // immune response // traceable author statement /// 0015833 // peptide transport // traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042886 // amide transport // traceable author statement /// 0050823 // peptide antigen stabilization // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0042824 // MHC class I peptide loading complex // non-traceable author statement /// 0042825 // TAP complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015433 // peptide antigen-transporting ATPase activity // traceable author statement /// 0042288 // MHC class I protein binding // traceable author statement /// 0042605 // peptide antigen binding // traceable author statement /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046978 // TAP1 binding // traceable author statement /// 0046979 // TAP2 binding // inferred from physical interaction /// 0046979 // TAP2 binding // traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 210295_at BC004105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004105.1 /DEF=Homo sapiens, melanoma antigen, family A, 10, clone MGC:10599, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 10 /DB_XREF=gi:13278641 /UG=Hs.18048 melanoma antigen, family A, 10 /FL=gb:NM_021048.1 gb:BC004105.1 BC004105 melanoma antigen family A, 10 MAGEA10 4109 NM_001011543 /// NM_001251828 /// NM_021048 0005634 // nucleus // inferred from electronic annotation 210296_s_at BC005375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005375.1 /DEF=Homo sapiens, peroxisomal membrane protein 3 (35kD, Zellweger syndrome), clone MGC:12491, mRNA, complete cds. /FEA=mRNA /PROD=peroxisomal membrane protein 3 (35kD, Zellwegersyndrome) /DB_XREF=gi:13529226 /UG=Hs.180612 peroxisomal membrane protein 3 (35kD, Zellweger syndrome) /FL=gb:BC005375.1 BC005375 peroxisomal biogenesis factor 2 PEX2 5828 NM_000318 /// NM_001079867 /// NM_001172086 /// NM_001172087 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210297_s_at U22178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U22178.1 /DEF=Human prostatic secretory protein 57 mRNA, complete cds. /FEA=mRNA /PROD=PSP57 /DB_XREF=gi:885984 /UG=Hs.183752 microseminoprotein, beta- /FL=gb:U22178.1 U22178 microseminoprotein, beta- MSMB 4477 NM_002443 /// NM_138634 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // traceable author statement 210298_x_at AF098518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098518.1 /DEF=Homo sapiens four and a half LIM domains 1 protein isoform B (FHL1) mRNA, complete cds. /FEA=mRNA /GEN=FHL1 /PROD=four and a half LIM domains 1 protein isoform B /DB_XREF=gi:3851649 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:AF098518.1 gb:AF063002.1 AF098518 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210299_s_at AF063002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF063002.1 /DEF=Homo sapiens LIM protein SLIMMER mRNA, complete cds. /FEA=mRNA /PROD=LIM protein SLIMMER /DB_XREF=gi:3859848 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:AF098518.1 gb:AF063002.1 AF063002 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210300_at AF152863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152863.1 /DEF=Homo sapiens GTPase GES (GES) mRNA, complete cds. /FEA=mRNA /GEN=GES /PROD=GTPase GES /DB_XREF=gi:8272461 /UG=Hs.247729 GTPase GES; REM protein /FL=gb:AF084465.1 gb:NM_014012.1 gb:AF152863.1 AF152863 RAS (RAD and GEM)-like GTP-binding 1 REM1 28954 NM_014012 /// XM_005260404 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 210301_at U06117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U06117.1 /DEF=Human xanthine dehydrogenase (XDH) mRNA, complete cds. /FEA=mRNA /GEN=XDH /PROD=xanthine dehydrogenase /DB_XREF=gi:984266 /UG=Hs.250 xanthene dehydrogenase /FL=gb:D11456.2 gb:U39487.1 gb:NM_000379.2 gb:U06117.1 U06117 xanthine dehydrogenase XDH 7498 NM_000379 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007595 // lactation // inferred from electronic annotation /// 0009115 // xanthine catabolic process // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045602 // negative regulation of endothelial cell differentiation // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1900747 // negative regulation of vascular endothelial growth factor signaling pathway // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001213 // negative regulation of vasculogenesis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004854 // xanthine dehydrogenase activity // inferred from direct assay /// 0004855 // xanthine oxidase activity // not recorded /// 0004855 // xanthine oxidase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043546 // molybdopterin cofactor binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay 210302_s_at AF262032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF262032.1 /DEF=Homo sapiens MAB21L2 protein (MAB21L2) mRNA, complete cds. /FEA=mRNA /GEN=MAB21L2 /PROD=MAB21L2 protein /DB_XREF=gi:9964006 /UG=Hs.251390 mab-21 (C. elegans)-like 2 /FL=gb:NM_006439.2 gb:AF262032.1 AF262032 mab-21-like 2 (C. elegans) MAB21L2 10586 NM_006439 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 210303_at AF262032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF262032.1 /DEF=Homo sapiens MAB21L2 protein (MAB21L2) mRNA, complete cds. /FEA=mRNA /GEN=MAB21L2 /PROD=MAB21L2 protein /DB_XREF=gi:9964006 /UG=Hs.251390 mab-21 (C. elegans)-like 2 /FL=gb:NM_006439.2 gb:AF262032.1 AF262032 mab-21-like 2 (C. elegans) MAB21L2 10586 NM_006439 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 210304_at BC000249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000249.1 /DEF=Homo sapiens, phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant), clone MGC:1689, mRNA, complete cds. /FEA=mRNA /PROD=phosphodiesterase 6B, cGMP-specific, rod, beta(congenital stationary night blindness 3, autosomaldominant) /DB_XREF=gi:12652976 /UG=Hs.2593 phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant) /FL=gb:BC000249.1 gb:NM_000283.1 BC000249 phosphodiesterase 6B, cGMP-specific, rod, beta PDE6B 5158 NM_000283 /// NM_001145291 /// NM_001145292 /// XM_005272279 /// XM_005272280 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009583 // detection of light stimulus // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0046037 // GMP metabolic process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from mutant phenotype 210305_at AB042557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042557.1 /DEF=Homo sapiens mRNA, similar to rat myomegalin, complete cds. /FEA=mRNA /DB_XREF=gi:11138039 /UG=Hs.265848 similar to rat myomegalin /FL=gb:AB042557.1 AB042557 phosphodiesterase 4D interacting protein PDE4DIP 9659 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_005272981 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 210306_at U89358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U89358.1 /DEF=Human l(3)mbt protein homolog mRNA, complete cds. /FEA=mRNA /PROD=l(3)mbt protein homolog /DB_XREF=gi:3811110 /UG=Hs.300863 lethal (3) malignant brain tumor l(3)mbt protein (Drosophila) homolog /FL=gb:U89358.1 U89358 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210307_s_at AL136796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136796.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K111 (from clone DKFZp434K111); complete cds. /FEA=mRNA /GEN=DKFZp434K111 /PROD=hypothetical protein /DB_XREF=gi:12053104 /UG=Hs.301338 hypothetical protein FLJ12587 /FL=gb:AL136796.1 AL136796 kelch-like family member 25 KLHL25 64410 NM_022480 /// XM_006720635 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 210309_at AB042823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042823.1 /DEF=Homo sapiens RECQL5 alpha mRNA for DNA helicase recQ5 alpha, complete cds. /FEA=mRNA /GEN=RECQL5 alpha /PROD=DNA helicase recQ5 alpha /DB_XREF=gi:7959110 /UG=Hs.33818 RecQ protein-like 5 /FL=gb:AB006533.1 gb:NM_004259.1 gb:AB042823.1 AB042823 RecQ protein-like 5 RECQL5 9400 NM_001003715 /// NM_001003716 /// NM_004259 /// XM_005257818 /// XM_005257822 /// XM_005257823 /// XM_006722186 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // non-traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // non-traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051304 // chromosome separation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210310_s_at AB016517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016517.1 /DEF=Homo sapiens mRNA for FGF-5S, complete cds. /FEA=mRNA /PROD=FGF-5S /DB_XREF=gi:3721901 /UG=Hs.37055 fibroblast growth factor 5 /FL=gb:AB016517.1 gb:AF171928.1 AB016517 fibroblast growth factor 5 FGF5 2250 NM_001291812 /// NM_004464 /// NM_033143 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 210311_at AF171928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF171928.1 /DEF=Homo sapiens fibroblast growth factor 5 short variant (FGF5) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=FGF5 /PROD=fibroblast growth factor 5 short variant /DB_XREF=gi:9622332 /UG=Hs.37055 fibroblast growth factor 5 /FL=gb:AB016517.1 gb:AF171928.1 AF171928 fibroblast growth factor 5 FGF5 2250 NM_001291812 /// NM_004464 /// NM_033143 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 210312_s_at BC002640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002640.1 /DEF=Homo sapiens, Similar to uterine protein, clone MGC:4279, mRNA, complete cds. /FEA=mRNA /PROD=Similar to uterine protein /DB_XREF=gi:12803610 /UG=Hs.4187 hypothetical protein 24636 /FL=gb:BC002640.1 BC002640 intraflagellar transport 20 homolog (Chlamydomonas) IFT20 90410 NM_001267774 /// NM_001267775 /// NM_001267776 /// NM_001267777 /// NM_001267778 /// NM_174887 0030030 // cell projection organization // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051642 // centrosome localization // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity /// 2000785 // regulation of autophagic vacuole assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044292 // dendrite terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210313_at AF041261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF041261.1 /DEF=Homo sapiens immunoglobulin-like transcript 7 mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 7 /DB_XREF=gi:4104890 /UG=Hs.48647 immunoglobulin-like transcript 7 /FL=gb:AF041261.1 AF041261 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 LILRA4 23547 NM_012276 0002376 // immune system process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210314_x_at AF114013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114013.1 /DEF=Homo sapiens tumor necrosis factor-related death ligand-1gamma mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor-related deathligand-1gamma /DB_XREF=gi:7328557 /UG=Hs.54673 tumor necrosis factor (ligand) superfamily, member 13 /FL=gb:AF136294.1 gb:AF114013.1 AF114013 tumor necrosis factor (ligand) superfamily, member 13 TNFSF13 8741 NM_001198622 /// NM_001198623 /// NM_001198624 /// NM_003808 /// NM_172087 /// NM_172088 /// NR_073490 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 210315_at AF077737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077737.1 /DEF=Homo sapiens synapsin IIb (SYN2) mRNA, complete cds. /FEA=mRNA /GEN=SYN2 /PROD=synapsin IIb /DB_XREF=gi:3511272 /UG=Hs.6439 synapsin II /FL=gb:U40215.1 gb:AF077737.1 gb:NM_003178.1 AF077737 synapsin II SYN2 6854 NM_003178 /// NM_133625 /// XM_006713311 /// XM_006713312 /// XM_006713313 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 210316_at U43143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43143.1 /DEF=Human receptor tyrosine kinase Flt4 (short form) mRNA, complete cds. /FEA=mRNA /PROD=Flt4 /DB_XREF=gi:1150990 /UG=Hs.74049 fms-related tyrosine kinase 4 /FL=gb:U43143.1 gb:NM_002020.1 U43143 fms-related tyrosine kinase 4 FLT4 2324 NM_002020 /// NM_182925 0001525 // angiogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0001946 // lymphangiogenesis // inferred from mutant phenotype /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from mutant phenotype /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from genetic interaction /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0060312 // regulation of blood vessel remodeling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from mutant phenotype /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 210317_s_at U28936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U28936.1 /DEF=Human epsilon 14-3-3 protein mRNA, complete cds. /FEA=mRNA /PROD=epsilon 14-3-3 protein /DB_XREF=gi:984318 /UG=Hs.79474 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, epsilon polypeptide /FL=gb:U28936.1 U28936 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon YWHAE 7531 NM_006761 /// NR_024058 /// XM_005256784 /// XM_006725298 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003064 // regulation of heart rate by hormone // non-traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0035308 // negative regulation of protein dephosphorylation // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred by curator /// 0086091 // regulation of heart rate by cardiac conduction // inferred by curator /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1902309 // negative regulation of peptidyl-serine dephosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005871 // kinesin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 210318_at J03912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03912.1 /DEF=Human interstitial retinol binding protein (IRBP) mRNA, complete cds. /FEA=mRNA /GEN=RBP3 /PROD=retinol-binding protein /DB_XREF=gi:186542 /UG=Hs.857 retinol-binding protein 3, interstitial /FL=gb:M22453.1 gb:J03912.1 gb:NM_002900.1 J03912 retinol binding protein 3, interstitial RBP3 5949 NM_002900 0001523 // retinoid metabolic process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0033165 // interphotoreceptor matrix // inferred from electronic annotation 0005501 // retinoid binding // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 210319_x_at D89377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89377.1 /DEF=Homo sapiens mRNA for MSX-2, complete cds. /FEA=mRNA /PROD=MSX-2 /DB_XREF=gi:1722693 /UG=Hs.89404 msh (Drosophila) homeo box homolog 2 /FL=gb:D89377.1 D89377 msh homeobox 2 MSX2 4488 NM_002449 /// XM_006714868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003416 // endochondral bone growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0035880 // embryonic nail plate morphogenesis // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // traceable author statement /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0061312 // BMP signaling pathway involved in heart development // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation /// 0090427 // activation of meiosis // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 2001055 // positive regulation of mesenchymal cell apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 210320_s_at AF077033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077033.1 /DEF=Homo sapiens putative ATP-dependent RNA helicase ROK1 mRNA, complete cds. /FEA=mRNA /PROD=putative ATP-dependent RNA helicase ROK1 /DB_XREF=gi:4689113 /UG=Hs.99423 ATP-dependent RNA helicase /FL=gb:AF077033.1 AF077033 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 DDX52 11056 NM_001291476 /// NM_007010 /// NM_152300 /// XM_006721650 /// XM_006725299 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210321_at M36118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36118.1 /DEF=Human cytotoxin serine protease-C mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181163 /UG=Hs.1051 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) /FL=gb:M36118.1 M36118 granzyme H (cathepsin G-like 2, protein h-CCPX) GZMH 2999 NM_001270780 /// NM_001270781 /// NM_033423 0006508 // proteolysis // not recorded /// 0006915 // apoptotic process // non-traceable author statement /// 0019835 // cytolysis // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210322_x_at AF000995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000995.1 /DEF=Homo sapiens ubiquitous TPR motif, Y isoform (UTY) mRNA, alternative transcript 2, complete cds. /FEA=mRNA /GEN=UTY /PROD=ubiquitous TPR motif, Y isoform /DB_XREF=gi:2580575 /UG=Hs.115277 ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome /FL=gb:AF000995.1 AF000995 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked UTY 7404 NM_001258249 /// NM_001258250 /// NM_001258251 /// NM_001258252 /// NM_001258253 /// NM_001258254 /// NM_001258255 /// NM_001258256 /// NM_001258257 /// NM_001258258 /// NM_001258259 /// NM_001258260 /// NM_001258261 /// NM_001258262 /// NM_001258263 /// NM_001258264 /// NM_001258265 /// NM_001258266 /// NM_001258267 /// NM_001258268 /// NM_001258269 /// NM_001258270 /// NM_007125 /// NM_182659 /// NM_182660 /// NR_047596 /// NR_047597 /// NR_047598 /// NR_047599 /// NR_047600 /// NR_047601 /// NR_047602 /// NR_047603 /// NR_047604 /// NR_047605 /// NR_047606 /// NR_047607 /// NR_047608 /// NR_047609 /// NR_047610 /// NR_047611 /// NR_047612 /// NR_047613 /// NR_047614 /// NR_047615 /// NR_047616 /// NR_047617 /// NR_047618 /// NR_047619 /// NR_047620 /// NR_047621 /// NR_047622 /// NR_047623 /// NR_047624 /// NR_047625 /// NR_047626 /// NR_047627 /// NR_047628 /// NR_047629 /// NR_047630 /// NR_047631 /// NR_047632 /// NR_047633 /// NR_047634 /// NR_047635 /// NR_047636 /// NR_047637 /// NR_047638 /// NR_047639 /// NR_047640 /// NR_047641 /// NR_047642 /// NR_047643 /// NR_047644 /// NR_047645 /// NR_047646 /// NR_047647 /// XM_005262518 /// XM_006724875 /// XM_006724876 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031935 // regulation of chromatin silencing // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from electronic annotation /// 0086003 // cardiac muscle cell contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 210323_at AB033823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB033823.1 /DEF=Homo sapiens mRNA for h-TEKTIN-t, complete cds. /FEA=mRNA /GEN=h-tektin-t /PROD=h-TEKTIN-t /DB_XREF=gi:6691549 /UG=Hs.127111 tektin 2 (testicular) /FL=gb:AF054910.1 gb:AB033823.1 gb:NM_014466.1 AB033823 tektin 2 (testicular) TEKT2 27285 NM_014466 /// XM_005270753 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001539 // cilium or flagellum-dependent cell motility // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 210324_at M17263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M17263.1 /DEF=Human complement protein C8 gamma subunit mRNA, complete cds. /FEA=mRNA /GEN=C8G /DB_XREF=gi:179723 /UG=Hs.1285 complement component 8, gamma polypeptide /FL=gb:M17999.1 gb:M17263.1 gb:NM_000606.1 M17263 complement component 8, gamma polypeptide C8G 733 NM_000606 /// XR_245338 0002376 // immune system process // inferred from electronic annotation /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation 210325_at M28825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M28825.1 /DEF=Human thymocyte antigen CD1a mRNA, complete cds. /FEA=mRNA /GEN=CD1A /DB_XREF=gi:180035 /UG=Hs.1309 CD1A antigen, a polypeptide /FL=gb:M28825.1 M28825 CD1a molecule CD1A 909 NM_001763 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030883 // endogenous lipid antigen binding // not recorded /// 0030884 // exogenous lipid antigen binding // not recorded /// 0071723 // lipopeptide binding // not recorded 210326_at D13368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13368.1 /DEF=Human mRNA for alanine:glyoxylate aminotransferase, complete cds. /FEA=mRNA /GEN=AGXT /PROD=alanine:glyoxylate aminotransferase /DB_XREF=gi:219432 /UG=Hs.144567 alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) /FL=gb:D13368.1 gb:NM_000030.1 D13368 alanine-glyoxylate aminotransferase AGXT 189 NM_000030 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009436 // glyoxylate catabolic process // inferred from direct assay /// 0019265 // glycine biosynthetic process, by transamination of glyoxylate // inferred from direct assay /// 0019448 // L-cysteine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042853 // L-alanine catabolic process // inferred from direct assay /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // inferred from mutant phenotype /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0046724 // oxalic acid secretion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004760 // serine-pyruvate transaminase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008453 // alanine-glyoxylate transaminase activity // inferred from direct assay /// 0008453 // alanine-glyoxylate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay 210327_s_at D13368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13368.1 /DEF=Human mRNA for alanine:glyoxylate aminotransferase, complete cds. /FEA=mRNA /GEN=AGXT /PROD=alanine:glyoxylate aminotransferase /DB_XREF=gi:219432 /UG=Hs.144567 alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) /FL=gb:D13368.1 gb:NM_000030.1 D13368 alanine-glyoxylate aminotransferase AGXT 189 NM_000030 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009436 // glyoxylate catabolic process // inferred from direct assay /// 0019265 // glycine biosynthetic process, by transamination of glyoxylate // inferred from direct assay /// 0019448 // L-cysteine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042853 // L-alanine catabolic process // inferred from direct assay /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // inferred from mutant phenotype /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0046724 // oxalic acid secretion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004760 // serine-pyruvate transaminase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008453 // alanine-glyoxylate transaminase activity // inferred from direct assay /// 0008453 // alanine-glyoxylate transaminase activity // traceable author statement /// 0008483 // transaminase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay 210328_at AF101477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF101477.1 /DEF=Homo sapiens glycine N-methyltransferase (GNMT) mRNA, complete cds. /FEA=mRNA /GEN=GNMT /PROD=glycine N-methyltransferase /DB_XREF=gi:8671583 /UG=Hs.144914 glycine N-methyltransferase /FL=gb:AF101477.1 gb:NM_018960.1 AF101477 glycine N-methyltransferase GNMT 27232 NM_018960 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006555 // methionine metabolic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0046500 // S-adenosylmethionine metabolic process // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005542 // folic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0017174 // glycine N-methyltransferase activity // inferred from direct assay 210329_s_at U58331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58331.1 /DEF=Human placental delta sarcoglycan mRNA, complete cds. /FEA=mRNA /PROD=delta sarcoglycan /DB_XREF=gi:1695856 /UG=Hs.151899 sarcoglycan, delta (35kD dystrophin-associated glycoprotein) /FL=gb:U58331.1 U58331 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) SGCD 6444 NM_000337 /// NM_001128209 /// NM_172244 /// XM_005265965 /// XM_005265966 /// XM_005265967 /// XM_006714911 /// XM_006714912 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210330_at U58331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58331.1 /DEF=Human placental delta sarcoglycan mRNA, complete cds. /FEA=mRNA /PROD=delta sarcoglycan /DB_XREF=gi:1695856 /UG=Hs.151899 sarcoglycan, delta (35kD dystrophin-associated glycoprotein) /FL=gb:U58331.1 U58331 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) SGCD 6444 NM_000337 /// NM_001128209 /// NM_172244 /// XM_005265965 /// XM_005265966 /// XM_005265967 /// XM_006714911 /// XM_006714912 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 210331_at AB048365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB048365.1 /DEF=Homo sapiens NEDL1 mRNA for NEDD4-like ubiquitin ligase 1, complete cds. /FEA=mRNA /GEN=NEDL1 /PROD=NEDD4-like ubiquitin ligase 1 /DB_XREF=gi:10039442 /UG=Hs.153685 KIAA0322 protein /FL=gb:AB048365.1 AB048365 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 HECW1 23072 NM_001287059 /// NM_015052 /// XM_005249665 /// XM_006715670 /// XM_006715671 /// XM_006715672 /// XM_006715673 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 210332_at M55040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M55040.1 /DEF=Human acetylcholinesterase (ACHE) mRNA, complete cds. /FEA=mRNA /GEN=ACHE /PROD=acetylcholinesterase /DB_XREF=gi:177974 /UG=Hs.154495 acetylcholinesterase (YT blood group) /FL=gb:M55040.1 M55040 acetylcholinesterase (Yt blood group) ACHE 43 NM_000665 /// NM_001282449 /// NM_015831 /// XM_005250357 /// XM_005250358 /// XM_006715994 /// XM_006715995 0001507 // acetylcholine catabolic process in synaptic cleft // non-traceable author statement /// 0001919 // regulation of receptor recycling // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from expression pattern /// 0006260 // DNA replication // traceable author statement /// 0006581 // acetylcholine catabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // not recorded /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // not recorded /// 0007416 // synapse assembly // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0019695 // choline metabolic process // not recorded /// 0031623 // receptor internalization // inferred from electronic annotation /// 0032223 // negative regulation of synaptic transmission, cholinergic // inferred by curator /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042982 // amyloid precursor protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045212 // neurotransmitter receptor biosynthetic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // not recorded /// 0050714 // positive regulation of protein secretion // traceable author statement /// 0050770 // regulation of axonogenesis // not recorded /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005605 // basal lamina // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // traceable author statement /// 0003990 // acetylcholinesterase activity // inferred from direct assay /// 0003990 // acetylcholinesterase activity // inferred from mutant phenotype /// 0004104 // cholinesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from direct assay /// 0017171 // serine hydrolase activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred from direct assay /// 0042166 // acetylcholine binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from electronic annotation 210333_at U76388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U76388.1 /DEF=Human steroidogenic factor 1 mRNA, complete cds. /FEA=mRNA /PROD=steroidogenic factor 1 /DB_XREF=gi:2052387 /UG=Hs.157037 nuclear receptor subfamily 5, group A, member 1 /FL=gb:U76388.1 gb:NM_004959.1 U76388 nuclear receptor subfamily 5, group A, member 1 NR5A1 2516 NM_004959 /// XM_005251871 /// XM_005251872 /// XM_005251873 0001553 // luteinization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007538 // primary sex determination // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0022414 // reproductive process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050810 // regulation of steroid biosynthetic process // traceable author statement /// 0051457 // maintenance of protein location in nucleus // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from direct assay /// 2000195 // negative regulation of female gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210334_x_at AB028869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB028869.1 /DEF=Homo sapiens mRNA for survivin-beta, complete cds. /FEA=mRNA /PROD=survivin-beta /DB_XREF=gi:7416052 /UG=Hs.1578 baculoviral IAP repeat-containing 5 (survivin) /FL=gb:AB028869.1 AB028869 baculoviral IAP repeat containing 5 BIRC5 332 NM_001012270 /// NM_001012271 /// NM_001168 /// XR_243654 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0050897 // cobalt ion binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction 210335_at AF056209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF056209.1 /DEF=Homo sapiens PAM COOH-terminal interactor protein 1 (PCIP1) mRNA, complete cds. /FEA=mRNA /GEN=PCIP1 /PROD=PAM COOH-terminal interactor protein 1 /DB_XREF=gi:3560562 /UG=Hs.159396 peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor protein-1 /FL=gb:NM_005447.2 gb:AF056209.1 AF056209 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 RASSF9 9182 NM_005447 0006605 // protein targeting // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016197 // endosomal transport // non-traceable author statement 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0012510 // trans-Golgi network transport vesicle membrane // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210336_x_at AF055078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF055078.1 /DEF=Homo sapiens zinc finger protein 42 (ZNF42) mRNA, alternate transcript, complete cds. /FEA=mRNA /GEN=ZNF42 /PROD=zinc finger protein 42 /DB_XREF=gi:5915897 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) /FL=gb:AF055078.1 AF055078 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210337_s_at U18197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18197.1 /DEF=Human ATP:citrate lyase mRNA, complete cds. /FEA=mRNA /PROD=ATP:citrate lyase /DB_XREF=gi:603073 /UG=Hs.174140 ATP citrate lyase /FL=gb:U18197.1 U18197 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 /// XM_005257393 /// XM_005257394 /// XM_005257395 0006101 // citrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009346 // citrate lyase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 210338_s_at AB034951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB034951.1 /DEF=Homo sapiens HSC54 mRNA for heat shock cognate protein 54, complete cds. /FEA=mRNA /GEN=HSC54 /PROD=heat shock cognate protein 54 /DB_XREF=gi:11526572 /UG=Hs.180414 heat shock 70kD protein 8 /FL=gb:AB034951.1 AB034951 heat shock 70kDa protein 8 /// small nucleolar RNA, C/D box 14C /// small nucleolar RNA, C/D box 14D HSPA8 /// SNORD14C /// SNORD14D 3312 /// 85389 /// 85390 NM_006597 /// NM_153201 /// NR_001453 /// NR_001454 /// XM_006718831 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1902904 // negative regulation of fibril organization // inferred from direct assay 0000974 // Prp19 complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 210339_s_at BC005196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005196.1 /DEF=Homo sapiens, kallikrein 2, prostatic, clone MGC:12201, mRNA, complete cds. /FEA=mRNA /PROD=kallikrein 2, prostatic /DB_XREF=gi:13528791 /UG=Hs.181350 kallikrein 2, prostatic /FL=gb:BC005196.1 gb:NM_005551.1 gb:AF188746.1 BC005196 kallikrein-related peptidase 2 KLK2 3817 NM_001002231 /// NM_001002232 /// NM_001256080 /// NM_005551 /// NR_045762 /// NR_045763 /// XM_006723206 /// XM_006723207 /// XM_006723208 /// XM_006723209 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210340_s_at BC002635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002635.1 /DEF=Homo sapiens, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), clone MGC:3848, mRNA, complete cds. /FEA=mRNA /PROD=colony stimulating factor 2 receptor, alpha,low-affinity (granulocyte-macrophage) /DB_XREF=gi:12803600 /UG=Hs.182378 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) /FL=gb:BC002635.1 BC002635 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CSF2RA 1438 NM_001161529 /// NM_001161530 /// NM_001161531 /// NM_001161532 /// NM_006140 /// NM_172245 /// NM_172246 /// NM_172247 /// NM_172248 /// NM_172249 /// NR_027760 /// XM_006724437 /// XM_006724438 /// XM_006724439 /// XM_006724440 /// XM_006724441 /// XM_006724858 /// XM_006724859 /// XM_006724860 /// XM_006724861 /// XM_006724862 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210341_at AB020642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020642.1 /DEF=Homo sapiens mRNA for KIAA0835 protein, complete cds. /FEA=mRNA /GEN=KIAA0835 /PROD=KIAA0835 protein /DB_XREF=gi:4240158 /UG=Hs.184628 hypothetical protein FLJ10883 /FL=gb:AB020642.1 AB020642 myelin transcription factor 1 MYT1 4661 NM_004535 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210342_s_at M17755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M17755.2 /DEF=Homo sapiens thyroid peroxidase (TPO) mRNA, complete cds. /FEA=mRNA /GEN=TPO /PROD=thyroid peroxidase /DB_XREF=gi:4680720 /UG=Hs.2041 thyroid peroxidase /FL=gb:NM_000547.1 gb:M17755.2 M17755 thyroid peroxidase TPO 7173 NM_000547 /// NM_001206744 /// NM_001206745 /// NM_175719 /// NM_175720 /// NM_175721 /// NM_175722 /// XM_005264698 /// XM_005264699 /// XM_005264700 /// XM_005264701 /// XM_005264702 /// XM_005264704 /// XM_005264705 /// XR_426959 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006590 // thyroid hormone generation // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035162 // embryonic hemopoiesis // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004447 // iodide peroxidase activity // inferred from electronic annotation /// 0004601 // peroxidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210343_s_at AF124373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF124373.1 /DEF=Homo sapiens organic anion transporter 1 (SLC22A6) mRNA, complete cds. /FEA=mRNA /GEN=SLC22A6 /PROD=organic anion transporter 1 /DB_XREF=gi:5901644 /UG=Hs.23965 solute carrier family 22 (organic anion transporter), member 6 /FL=gb:AF104038.1 gb:AF097490.1 gb:AB009698.1 gb:NM_004790.1 gb:AF124373.1 gb:AF057039.2 AF124373 solute carrier family 22 (organic anion transporter), member 6 SLC22A6 9356 NM_004790 /// NM_153276 /// NM_153277 /// NM_153278 /// NM_153279 0006820 // anion transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from direct assay /// 0015711 // organic anion transport // inferred from mutant phenotype /// 0015742 // alpha-ketoglutarate transport // inferred from direct assay /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // inferred from direct assay /// 0043252 // sodium-independent organic anion transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0097254 // renal tubular secretion // inferred from mutant phenotype /// 0097254 // renal tubular secretion // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005452 // inorganic anion exchanger activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0008514 // organic anion transmembrane transporter activity // inferred from mutant phenotype /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 210344_at AF323729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF323729.1 /DEF=Homo sapiens OSBP-related protein 7 mRNA, complete cds. /FEA=mRNA /PROD=OSBP-related protein 7 /DB_XREF=gi:12382788 /UG=Hs.274370 hypothetical protein FLJ20260 /FL=gb:AF323729.1 AF323729 oxysterol binding protein-like 7 OSBPL7 114881 NM_017731 /// NM_145798 /// XM_005257010 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 1901800 // positive regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 210345_s_at AF257737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF257737.1 /DEF=Homo sapiens ciliary dynein heavy chain 9 (DNAH9) mRNA, complete cds. /FEA=mRNA /GEN=DNAH9 /PROD=ciliary dynein heavy chain 9 /DB_XREF=gi:7739766 /UG=Hs.284259 dynein, axonemal, heavy polypeptide 9 /FL=gb:AF257737.1 AF257737 dynein, axonemal, heavy chain 9 DNAH9 1770 NM_001372 /// NM_004662 /// XM_006721465 /// XM_006721466 /// XM_006721467 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 210346_s_at AF212224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF212224.1 /DEF=Homo sapiens CLK4 mRNA, complete cds. /FEA=mRNA /PROD=CLK4 /DB_XREF=gi:9437514 /UG=Hs.295231 Homo sapiens CLK4 mRNA, complete cds /FL=gb:AF212224.1 AF212224 CDC-like kinase 4 CLK4 57396 NM_020666 /// XM_005265947 /// XM_005265948 /// XM_005265949 /// XM_006714895 /// XM_006714896 /// XR_427807 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210347_s_at AF080216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080216.1 /DEF=Homo sapiens C2H2-type zinc-finger protein mRNA, complete cds. /FEA=mRNA /PROD=C2H2-type zinc-finger protein /DB_XREF=gi:12150277 /UG=Hs.307051 Homo sapiens C2H2-type zinc-finger protein mRNA, complete cds /FL=gb:AF080216.1 AF080216 B-cell CLL/lymphoma 11A (zinc finger protein) BCL11A 53335 NM_018014 /// NM_022893 /// NM_138553 /// NM_138559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // non-traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0032463 // negative regulation of protein homooligomerization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048671 // negative regulation of collateral sprouting // inferred from mutant phenotype /// 0048672 // positive regulation of collateral sprouting // inferred from mutant phenotype /// 0050773 // regulation of dendrite development // inferred from mutant phenotype /// 2000171 // negative regulation of dendrite development // inferred from mutant phenotype /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 210348_at AF176379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF176379.1 /DEF=Homo sapiens ARTS protein (PNUTL2) mRNA, complete cds; nuclear gene for mitochondrial product. /FEA=mRNA /GEN=PNUTL2 /PROD=ARTS protein /DB_XREF=gi:12024870 /UG=Hs.307091 Homo sapiens ARTS protein (PNUTL2) mRNA, complete cds; nuclear gene for mitochondrial product /FL=gb:AF176379.1 AF176379 septin 4 SEPT4 5414 NM_001198713 /// NM_001256782 /// NM_001256822 /// NM_004574 /// NM_080415 /// NM_080416 /// NM_080417 /// NR_037155 /// NR_104196 /// NR_104197 /// XM_006721949 /// XM_006721950 /// XM_006721951 /// XM_006721952 /// XM_006721953 /// XM_006721954 /// XM_006721955 0000910 // cytokinesis // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0030382 // sperm mitochondrion organization // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048240 // sperm capacitation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 210349_at L24959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L24959.1 /DEF=Human calciumcalmodulin dependent protein kinase mRNA, complete cds. /FEA=mRNA /PROD=calciumcalmodulin dependent protein kinase /DB_XREF=gi:407005 /UG=Hs.348 calciumcalmodulin-dependent protein kinase IV /FL=gb:L17000.1 gb:L24959.1 gb:NM_001744.1 gb:D30742.1 L24959 calcium/calmodulin-dependent protein kinase IV CAMK4 814 NM_001744 0002372 // myeloid dendritic cell cytokine production // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007616 // long-term memory // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // traceable author statement /// 0043011 // myeloid dendritic cell differentiation // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045670 // regulation of osteoclast differentiation // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210350_x_at AF044076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF044076.1 /DEF=Homo sapiens candidate tumor suppressor p33ING1 (ING1) mRNA, complete cds. /FEA=mRNA /GEN=ING1 /PROD=candidate tumor suppressor p33ING1 /DB_XREF=gi:2829207 /UG=Hs.46700 inhibitor of growth 1 family, member 1 /FL=gb:AF078835.1 gb:AF044076.1 gb:AB024401.1 gb:AF181850.1 gb:AF149721.1 AF044076 inhibitor of growth family, member 1 ING1 3621 NM_001267728 /// NM_005537 /// NM_198217 /// NM_198218 /// NM_198219 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210352_at AL136823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136823.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P2326 (from clone DKFZp434P2326); complete cds. /FEA=mRNA /GEN=DKFZp434P2326 /PROD=hypothetical protein /DB_XREF=gi:12053156 /UG=Hs.5464 thyroid hormone receptor coactivating protein /FL=gb:AL136823.1 AL136823 bromodomain containing 8 BRD8 10902 NM_001164326 /// NM_006696 /// NM_139199 /// NM_183359 /// XM_005271855 /// XM_005271856 /// XM_005271857 /// XM_005271859 /// XM_005271860 /// XM_005271861 /// XM_005271864 /// XM_005271865 /// XM_006714524 /// XM_006714525 /// XR_427701 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210353_s_at M65105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M65105.1 /DEF=Human noradrenaline transporter mRNA, complete cds. /FEA=mRNA /GEN=NAT1 /PROD=noradrenaline transporter /DB_XREF=gi:189257 /UG=Hs.78036 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 /FL=gb:M65105.1 gb:NM_001043.1 M65105 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 210354_at M29383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29383.1 /DEF=Human interferon-gamma (HuIFN-gamma) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:186514 /UG=Hs.856 interferon, gamma /FL=gb:NM_000619.1 gb:M29383.1 M29383 interferon, gamma IFNG 3458 NM_000619 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001781 // neutrophil apoptotic process // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // not recorded /// 0002302 // CD8-positive, alpha-beta T cell differentiation involved in immune response // inferred from electronic annotation /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032700 // negative regulation of interleukin-17 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // inferred from direct assay /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // non-traceable author statement /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0044146 // negative regulation of growth of symbiont involved in interaction with host // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from electronic annotation /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051712 // positive regulation of killing of cells of other organism // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060550 // positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity // inferred from direct assay /// 0060552 // positive regulation of fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0060557 // positive regulation of vitamin D biosynthetic process // inferred from direct assay /// 0060559 // positive regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071351 // cellular response to interleukin-18 // inferred from electronic annotation /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2000309 // positive regulation of tumor necrosis factor (ligand) superfamily member 11 production // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // not recorded /// 0005133 // interferon-gamma receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210355_at J03580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03580.1 /DEF=Human, parathyroid-like protein (associated with humoral hypercalcemia of malignancy) mRNA, complete cds. /FEA=mRNA /GEN=PTHLH /DB_XREF=gi:190705 /UG=Hs.89626 parathyroid hormone-like hormone /FL=gb:J03580.1 J03580 parathyroid hormone-like hormone PTHLH 5744 NM_002820 /// NM_198964 /// NM_198965 /// NM_198966 /// XM_005253434 /// XM_006719115 0001501 // skeletal system development // inferred from direct assay /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0016485 // protein processing // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046058 // cAMP metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060649 // mammary gland bud elongation // inferred from electronic annotation /// 0060659 // nipple sheath formation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from direct assay 210356_x_at BC002807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002807.1 /DEF=Homo sapiens, membrane-spanning 4-domains, subfamily A, member 2, clone MGC:3969, mRNA, complete cds. /FEA=mRNA /PROD=membrane-spanning 4-domains, subfamily A, member2 /DB_XREF=gi:12803920 /UG=Hs.89751 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) /FL=gb:NM_021950.1 gb:BC002807.1 BC002807 membrane-spanning 4-domains, subfamily A, member 1 MS4A1 931 NM_021950 /// NM_152866 0006955 // immune response // traceable author statement /// 0006959 // humoral immune response // non-traceable author statement /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay 210357_s_at BC000669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000669.1 /DEF=Homo sapiens, Similar to hypothetical protein, clone MGC:1010, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein /DB_XREF=gi:12653766 /UG=Hs.92374 hypothetical protein /FL=gb:BC000669.1 BC000669 spermine oxidase SMOX 54498 NM_001270691 /// NM_175839 /// NM_175840 /// NM_175841 /// NM_175842 /// XM_006723578 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046208 // spermine catabolic process // inferred from direct assay /// 0046208 // spermine catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046592 // polyamine oxidase activity // inferred from direct assay /// 0052894 // norspermine:oxygen oxidoreductase activity // inferred from electronic annotation /// 0052895 // N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity // inferred from electronic annotation /// 0052901 // spermine:oxygen oxidoreductase (spermidine-forming) activity // inferred from electronic annotation 210358_x_at BC002557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002557.1 /DEF=Homo sapiens, Similar to GATA-binding protein 2, clone MGC:2306, mRNA, complete cds. /FEA=mRNA /PROD=Similar to GATA-binding protein 2 /DB_XREF=gi:12803464 /UG=Hs.760 GATA-binding protein 2 /FL=gb:BC002557.1 BC002557 GATA binding protein 2 GATA2 2624 NM_001145661 /// NM_001145662 /// NM_032638 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0021514 // ventral spinal cord interneuron differentiation // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035065 // regulation of histone acetylation // inferred from electronic annotation /// 0035854 // eosinophil fate commitment // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048469 // cell maturation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060872 // semicircular canal development // inferred from electronic annotation /// 0070345 // negative regulation of fat cell proliferation // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 210359_at AF116674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116674.1 /DEF=Homo sapiens PRO1941 mRNA, complete cds. /FEA=mRNA /PROD=PRO1941 /DB_XREF=gi:7959846 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AF116674.1 AF116674 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 210360_s_at AF116674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116674.1 /DEF=Homo sapiens PRO1941 mRNA, complete cds. /FEA=mRNA /PROD=PRO1941 /DB_XREF=gi:7959846 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AF116674.1 AF116674 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 210361_s_at AF256223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF256223.1 /DEF=Homo sapiens ets family transcription factor ELF2B (ELF2) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=ELF2 /PROD=ets family transcription factor ELF2B /DB_XREF=gi:7677545 /UG=Hs.82143 E74-like factor 2 (ets domain transcription factor) /FL=gb:AF256223.1 AF256223 E74-like factor 2 (ets domain transcription factor) ELF2 1998 NM_001276457 /// NM_001276458 /// NM_001276459 /// NM_006874 /// NM_201999 /// XM_005262803 /// XM_005262804 /// XM_005262805 /// XM_005262806 /// XM_006714128 /// XM_006714129 /// XM_006714130 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210362_x_at AF230409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230409.1 /DEF=Homo sapiens tripartite motif protein TRIM19 iota mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM19 iota /DB_XREF=gi:12275906 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230407.1 gb:AF230409.1 AF230409 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 210363_s_at AF107028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF107028.1 /DEF=Homo sapiens sodium channel beta 2 subunit (SCN2B) mRNA, complete cds. /FEA=mRNA /GEN=SCN2B /PROD=sodium channel beta 2 subunit /DB_XREF=gi:5702193 /UG=Hs.129783 sodium channel, voltage-gated, type II, beta polypeptide /FL=gb:AF049498.1 gb:AF007783.1 gb:NM_004588.1 gb:AF107028.1 gb:U87555.1 AF107028 sodium channel, voltage-gated, type II, beta subunit SCN2B 6327 NM_004588 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0001518 // voltage-gated sodium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype 210364_at U87555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87555.1 /DEF=Human sodium channel beta 2 subunit (SCN2B) mRNA, complete cds. /FEA=mRNA /GEN=SCN2B /PROD=sodium channel beta 2 subunit /DB_XREF=gi:6649596 /UG=Hs.129783 sodium channel, voltage-gated, type II, beta polypeptide /FL=gb:AF049498.1 gb:AF007783.1 gb:NM_004588.1 gb:AF107028.1 gb:U87555.1 U87555 sodium channel, voltage-gated, type II, beta subunit SCN2B 6327 NM_004588 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay 0001518 // voltage-gated sodium channel complex // inferred from direct assay /// 0001518 // voltage-gated sodium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0086006 // voltage-gated sodium channel activity involved in cardiac muscle cell action potential // inferred from mutant phenotype 210365_at D43967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D43967.1 /DEF=Human AML1 mRNA for AML1a protein (alternatively spliced product), complete cds. /FEA=mRNA /GEN=AML1 /PROD=AML1a protein /DB_XREF=gi:966994 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:M83215.1 gb:D43967.1 D43967 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 210366_at AB026257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026257.1 /DEF=Homo sapiens mRNA for organic anion transporter OATP-C, complete cds. /FEA=mRNA /GEN=OATP-C /PROD=organic anion transporter OATP-C /DB_XREF=gi:5006264 /UG=Hs.137425 solute carrier family 21 (organic anion transporter), member 6 /FL=gb:AB026257.1 gb:AF060500.1 gb:NM_006446.1 gb:AF205071.1 AB026257 solute carrier organic anion transporter family, member 1B1 SLCO1B1 10599 NM_006446 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // traceable author statement 210367_s_at AF010316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010316.1 /DEF=Homo sapiens Pig12 (PIG12) mRNA, complete cds. /FEA=mRNA /GEN=PIG12 /PROD=Pig12 /DB_XREF=gi:2415307 /UG=Hs.146688 prostaglandin E synthase /FL=gb:AF010316.1 AF010316 prostaglandin E synthase PTGES 9536 NM_004878 /// NM_198797 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0016853 // isomerase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from direct assay /// 0050220 // prostaglandin-E synthase activity // not recorded /// 0050220 // prostaglandin-E synthase activity // inferred from direct assay 210368_at AB002325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002325.1 /DEF=Homo sapiens mRNA for KIAA0327 protein, complete cds. /FEA=mRNA /GEN=KIAA0327 /PROD=KIAA0327 protein /DB_XREF=gi:2224594 /UG=Hs.149323 protocadherin gamma subfamily A, 8 /FL=gb:AB002325.1 gb:AF152515.1 gb:NM_014004.1 AB002325 protocadherin gamma subfamily A, 8 PCDHGA8 9708 NM_014004 /// NM_032088 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210369_at BC000134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000134.2 /DEF=Homo sapiens, Similar to SWAP-70 protein, clone MGC:5327, mRNA, complete cds. /FEA=mRNA /PROD=Similar to SWAP-70 protein /DB_XREF=gi:13111791 /UG=Hs.153026 SWAP-70 protein /FL=gb:BC000134.2 BC000134 SWAP switching B-cell complex 70kDa subunit SWAP70 23075 NM_015055 /// XM_005252829 /// XM_005252830 0016444 // somatic cell DNA recombination // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 210370_s_at AF244129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF244129.1 /DEF=Homo sapiens cell-surface molecule Ly-9 mRNA, complete cds. /FEA=mRNA /PROD=cell-surface molecule Ly-9 /DB_XREF=gi:10197716 /UG=Hs.153042 lymphocyte antigen 9 /FL=gb:AF244129.1 AF244129 lymphocyte antigen 9 LY9 4063 NM_001033667 /// NM_001261456 /// NM_001261457 /// NM_002348 /// XM_005245164 /// XM_006711320 /// XM_006711321 /// XM_006711322 /// XM_006711323 /// XM_006711324 /// XM_006711325 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation 210371_s_at BC003092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003092.1 /DEF=Homo sapiens, Similar to retinoblastoma binding protein 4, clone MGC:1393, mRNA, complete cds. /FEA=mRNA /PROD=Similar to retinoblastoma binding protein 4 /DB_XREF=gi:13111850 /UG=Hs.16003 retinoblastoma-binding protein 4 /FL=gb:BC003092.1 gb:NM_005610.1 BC003092 retinoblastoma binding protein 4 RBBP4 5928 NM_001135255 /// NM_001135256 /// NM_005610 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016580 // Sin3 complex // non-traceable author statement /// 0016581 // NuRD complex // inferred from direct assay /// 0016581 // NuRD complex // non-traceable author statement /// 0016589 // NURF complex // inferred from direct assay /// 0033186 // CAF-1 complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // non-traceable author statement /// 0042826 // histone deacetylase binding // inferred from physical interaction 210372_s_at AF208012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF208012.1 /DEF=Homo sapiens tumor protein D52-like 2 (TPD52L2) mRNA, complete cds. /FEA=mRNA /GEN=TPD52L2 /PROD=tumor protein D52-like 2 /DB_XREF=gi:12246900 /UG=Hs.16611 tumor protein D52-like 1 /FL=gb:AF208012.1 AF208012 tumor protein D52-like 1 TPD52L1 7164 NM_001003395 /// NM_001003396 /// NM_001003397 /// NM_001292026 /// NM_003287 /// XM_005267121 /// XM_005267122 /// XM_005267123 /// XM_005267124 /// XM_006715556 /// XM_006715557 /// XM_006715558 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 210373_at AF040708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040708.1 /DEF=Homo sapiens candidate tumor suppressor gene 21 protein mRNA, complete cds. /FEA=mRNA /PROD=candidate tumor suppressor gene 21 protein /DB_XREF=gi:2935584 /UG=Hs.169780 homologous to yeast nitrogen permease (candidate tumor suppressor) /FL=gb:AF040708.1 AF040708 nitrogen permease regulator-like 2 (S. cerevisiae) NPRL2 10641 NM_006545 /// XM_005264806 /// XM_005264808 /// XM_006712937 0006468 // protein phosphorylation // inferred from direct assay /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210374_x_at D38300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38300.1 /DEF=Homo sapiens mRNA for prostaglandin E receotor EP3 subtype 4 isoform, complete cds. /FEA=mRNA /PROD=prostaglandin E receotor EP3 subtype 4 isoform /DB_XREF=gi:1389571 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38300.1 gb:U13214.1 D38300 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210375_at X83858 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83858.1 /DEF=H.sapiens mRNA for prostaglandin E receptor (EP3a2). /FEA=mRNA /PROD=prostaglandin E receptor, subtype EP3a2 /DB_XREF=gi:633209 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38297.1 gb:L27490.1 gb:L26976.1 gb:U13218.1 X83858 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 210376_x_at M25269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25269.1 /DEF=Homo sapiens tyrosine kinase (ELK1) oncogene mRNA, complete cds. /FEA=mRNA /GEN=ELK1 /PROD=tyrosine kinase /DB_XREF=gi:538208 /UG=Hs.181128 ELK1, member of ETS oncogene family /FL=gb:M25269.1 M25269 ELK1, member of ETS oncogene family ELK1 2002 NM_001114123 /// NM_001257168 /// NM_005229 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210377_at D16350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D16350.1 /DEF=Human SA mRNA for SA gene product, complete cds. /FEA=mRNA /GEN=SA /DB_XREF=gi:471131 /UG=Hs.181345 SA (rat hypertension-associated) homolog /FL=gb:D16350.1 D16350 acyl-CoA synthetase medium-chain family member 3 ACSM3 6296 NM_005622 /// NM_202000 /// XM_005255466 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0042632 // cholesterol homeostasis // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015645 // fatty acid ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 210378_s_at BC004118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004118.1 /DEF=Homo sapiens, clone MGC:11170, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11170) /DB_XREF=gi:13278674 /UG=Hs.18528 Sjogrens syndrome nuclear autoantigen 1 /FL=gb:BC004118.1 BC004118 Sjogren syndrome nuclear autoantigen 1 SSNA1 8636 NM_003731 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 210379_s_at AF162666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF162666.1 /DEF=Homo sapiens tousled-like kinase 1 (TLK1) mRNA, complete cds. /FEA=mRNA /GEN=TLK1 /PROD=tousled-like kinase 1 /DB_XREF=gi:6063016 /UG=Hs.18895 tousled-like kinase 1 /FL=gb:AF162666.1 AF162666 tousled-like kinase 1 TLK1 9874 NM_001136554 /// NM_001136555 /// NM_012290 /// XM_005246981 /// XM_006712883 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210380_s_at AF126966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF126966.1 /DEF=Homo sapiens voltage-dependent calcium channel alpha 1G subunit a isoform (CACNA1G) mRNA, complete cds. /FEA=mRNA /GEN=CACNA1G /PROD=voltage-dependent calcium channel alpha 1Gsubunit a isoform /DB_XREF=gi:4761540 /UG=Hs.194746 calcium channel, voltage-dependent, alpha 1G subunit /FL=gb:AF126966.1 gb:AF190860.1 AF126966 calcium channel, voltage-dependent, T type, alpha 1G subunit CACNA1G 8913 NM_001256324 /// NM_001256325 /// NM_001256326 /// NM_001256327 /// NM_001256328 /// NM_001256329 /// NM_001256330 /// NM_001256331 /// NM_001256332 /// NM_001256333 /// NM_001256334 /// NM_001256359 /// NM_001256360 /// NM_001256361 /// NM_018896 /// NM_198376 /// NM_198377 /// NM_198378 /// NM_198379 /// NM_198380 /// NM_198382 /// NM_198383 /// NM_198384 /// NM_198385 /// NM_198386 /// NM_198387 /// NM_198388 /// NM_198396 /// NM_198397 /// NR_046054 /// NR_046055 /// NR_046056 /// NR_046057 /// NR_046058 /// XM_006722160 /// XM_006722161 0001508 // action potential // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010045 // response to nickel cation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 210381_s_at BC000740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000740.1 /DEF=Homo sapiens, cholecystokinin B receptor, clone MGC:2199, mRNA, complete cds. /FEA=mRNA /PROD=cholecystokinin B receptor /DB_XREF=gi:12653894 /UG=Hs.203 cholecystokinin B receptor /FL=gb:L07746.1 gb:BC000740.1 gb:L04473.1 gb:L08112.1 gb:NM_000731.1 gb:S70057.1 BC000740 cholecystokinin B receptor CCKBR 887 NM_176875 /// XM_005253210 0001696 // gastric acid secretion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007586 // digestion // traceable author statement /// 0007600 // sensory perception // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0038188 // cholecystokinin signaling pathway // traceable author statement /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004951 // cholecystokinin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015054 // gastrin receptor activity // inferred from direct assay /// 0031741 // type B gastrin/cholecystokinin receptor binding // inferred from direct assay /// 0046935 // 1-phosphatidylinositol-3-kinase regulator activity // traceable author statement 210382_at U13989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13989.1 /DEF=Human secretin receptor mRNA, complete cds. /FEA=mRNA /PROD=secretin receptor /DB_XREF=gi:763533 /UG=Hs.2199 secretin receptor /FL=gb:NM_002980.1 gb:U20178.1 gb:U13989.1 gb:U28281.1 U13989 secretin receptor SCTR 6344 NM_002980 /// XM_005263730 /// XM_006712683 /// XM_006712684 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0007588 // excretion // traceable author statement 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0015055 // secretin receptor activity // traceable author statement 210383_at AF225985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225985.1 /DEF=Homo sapiens voltage-gated sodium channel alpha subunit SCN1A (SCN1A) mRNA, complete cds. /FEA=mRNA /GEN=SCN1A /PROD=voltage-gated sodium channel alpha subunitSCN1A /DB_XREF=gi:12642269 /UG=Hs.22654 sodium channel, voltage-gated, type I, alpha polypeptide /FL=gb:AF225985.1 AF225985 sodium channel, voltage-gated, type I, alpha subunit SCN1A 6323 NM_001165963 /// NM_001165964 /// NM_001202435 /// NM_006920 0001508 // action potential // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008627 // intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from electronic annotation /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0034706 // sodium channel complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // non-traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation 210384_at U79286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79286.1 /DEF=Human arginine methyltransferase mRNA, complete cds. /FEA=mRNA /PROD=arginine methyltransferase /DB_XREF=gi:1710262 /UG=Hs.235887 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 /FL=gb:U79286.1 U79286 protein arginine methyltransferase 2 PRMT2 3275 NM_001242864 /// NM_001242865 /// NM_001242866 /// NM_001286676 /// NM_001286677 /// NM_001286678 /// NM_001535 /// NM_206962 /// XM_005261111 /// XM_006723998 /// XM_006723999 /// XM_006724000 0006479 // protein methylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0035246 // peptidyl-arginine N-methylation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048588 // developmental cell growth // inferred from sequence or structural similarity /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035189 // Rb-E2F complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0008469 // histone-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0033142 // progesterone receptor binding // inferred from physical interaction /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 210385_s_at AF106037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF106037.1 /DEF=Homo sapiens adipocyte-derived leucine aminopeptidase mRNA, complete cds. /FEA=mRNA /PROD=adipocyte-derived leucine aminopeptidase /DB_XREF=gi:6381988 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator /FL=gb:AF106037.1 AF106037 endoplasmic reticulum aminopeptidase 1 ERAP1 51752 NM_001040458 /// NM_001198541 /// NM_016442 /// XM_005272015 /// XM_005272016 0001525 // angiogenesis // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009617 // response to bacterium // inferred from expression pattern /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // non-traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement /// 0045088 // regulation of innate immune response // non-traceable author statement /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210386_s_at BC001906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001906.1 /DEF=Homo sapiens, Similar to metaxin 1, clone MGC:2518, mRNA, complete cds. /FEA=mRNA /PROD=Similar to metaxin 1 /DB_XREF=gi:12804906 /UG=Hs.247551 metaxin 1 /FL=gb:BC001906.1 BC001906 metaxin 1 MTX1 4580 NM_002455 /// NM_198883 /// XM_006711338 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210387_at BC001131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001131.1 /DEF=Homo sapiens, H2B histone family, member A, clone MGC:2561, mRNA, complete cds. /FEA=mRNA /PROD=H2B histone family, member A /DB_XREF=gi:12654590 /UG=Hs.247817 H2B histone family, member A /FL=gb:BC001131.1 gb:NM_003518.1 BC001131 histone cluster 1, H2bg /// histone cluster 1, H2bj HIST1H2BG /// HIST1H2BJ 8339 /// 8970 NM_003518 /// NM_021058 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210388_at BC000939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000939.2 /DEF=Homo sapiens, phospholipase C, beta 2, clone MGC:5181, mRNA, complete cds. /FEA=mRNA /PROD=phospholipase C, beta 2 /DB_XREF=gi:12803010 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:BC000939.2 BC000939 phospholipase C, beta 2 PLCB2 5330 NM_001284297 /// NM_001284298 /// NM_001284299 /// NM_004573 /// XM_005254448 /// XM_005254449 /// XM_005254450 /// XM_006720571 /// XM_006720572 /// XR_243102 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210389_x_at BC000258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000258.1 /DEF=Homo sapiens, Similar to delta-tubulin, clone MGC:2619, mRNA, complete cds. /FEA=mRNA /PROD=Similar to delta-tubulin /DB_XREF=gi:12652994 /UG=Hs.270847 delta-tubulin /FL=gb:BC000258.1 BC000258 tubulin, delta 1 TUBD1 51174 NM_001193609 /// NM_001193610 /// NM_001193611 /// NM_001193612 /// NM_001193613 /// NM_016261 /// XM_005257425 /// XM_005257426 /// XM_005257427 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 210390_s_at AF031587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031587.1 /DEF=Homo sapiens MIP-1 delta mRNA, complete cds. /FEA=mRNA /PROD=MIP-1 delta /DB_XREF=gi:2739163 /UG=Hs.272493 small inducible cytokine subfamily A (Cys-Cys), member 15 /FL=gb:AF031587.1 gb:U58914.1 AF031587 chemokine (C-C motif) ligand 15 /// CCL15-CCL14 readthrough (NMD candidate) CCL15 /// CCL15-CCL14 6359 /// 348249 NM_004167 /// NM_032964 /// NM_032965 /// NR_027921 /// NR_027922 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0050918 // positive chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay 210391_at X99975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X99975.1 /DEF=H.sapiens mRNA for hRTRhGCNF protein. /FEA=mRNA /PROD=hRTRhGCNF protein /DB_XREF=gi:1491715 /UG=Hs.278599 nuclear receptor subfamily 6, group A, member 1 /FL=gb:U80802.1 X99975 nuclear receptor subfamily 6, group A, member 1 NR6A1 2649 NM_001278546 /// NM_001489 /// NM_033334 /// NM_033335 /// XM_005251917 /// XM_005251918 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007276 // gamete generation // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 210392_x_at U80802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U80802.1 /DEF=Homo sapiens orphan nuclear receptor GCNF mRNA, complete cds. /FEA=mRNA /PROD=orphan nuclear receptor GCNF /DB_XREF=gi:1737483 /UG=Hs.278599 nuclear receptor subfamily 6, group A, member 1 /FL=gb:U80802.1 U80802 nuclear receptor subfamily 6, group A, member 1 NR6A1 2649 NM_001278546 /// NM_001489 /// NM_033334 /// NM_033335 /// XM_005251917 /// XM_005251918 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007276 // gamete generation // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 210393_at AF062006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062006.1 /DEF=Homo sapiens orphan G protein-coupled receptor HG38 mRNA, complete cds. /FEA=mRNA /PROD=orphan G protein-coupled receptor HG38 /DB_XREF=gi:3366801 /UG=Hs.285529 G protein-coupled receptor 49 /FL=gb:AF062006.1 gb:AF061444.1 gb:NM_003667.1 AF062006 leucine-rich repeat containing G protein-coupled receptor 5 LGR5 8549 NM_001277226 /// NM_001277227 /// NM_003667 /// NR_110596 /// XM_005269204 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 210394_x_at BC005325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005325.1 /DEF=Homo sapiens, synovial sarcoma, X breakpoint 4, clone MGC:12411, mRNA, complete cds. /FEA=mRNA /PROD=synovial sarcoma, X breakpoint 4 /DB_XREF=gi:13529094 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 /FL=gb:BC005325.1 BC005325 synovial sarcoma, X breakpoint 4 /// synovial sarcoma, X breakpoint 4B SSX4 /// SSX4B 6759 /// 548313 NM_001034832 /// NM_001040612 /// NM_005636 /// NM_175729 /// XM_006726844 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 210395_x_at AF116676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116676.1 /DEF=Homo sapiens PRO1957 mRNA, complete cds. /FEA=mRNA /PROD=PRO1957 /DB_XREF=gi:7959850 /UG=Hs.298161 myosin, light polypeptide 4, alkali; atrial, embryonic /FL=gb:AF116676.1 AF116676 myosin, light chain 4, alkali; atrial, embryonic MYL4 4635 NM_001002841 /// NM_002476 /// XM_005257391 /// XM_005257392 0002026 // regulation of the force of heart contraction // inferred from mutant phenotype /// 0007517 // muscle organ development // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0031672 // A band // inferred from mutant phenotype 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0032038 // myosin II heavy chain binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from mutant phenotype 210396_s_at AF271775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF271775.1 /DEF=Homo sapiens DC49 mRNA, complete cds. /FEA=mRNA /PROD=DC49 /DB_XREF=gi:12006206 /UG=Hs.307093 Homo sapiens DC49 mRNA, complete cds /FL=gb:AF271775.1 AF271775 bolA family member 2 /// SMG1 pseudogene 2 /// SMG1 pseudogene 5 BOLA2 /// SMG1P2 /// SMG1P5 440354 /// 552900 /// 595101 NM_001031827 /// NM_001031833 /// NR_002453 /// NR_002473 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210397_at U73945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73945.1 /DEF=Human beta-defensin-1 mRNA, complete cds. /FEA=mRNA /PROD=beta-defensin-1 /DB_XREF=gi:1755147 /UG=Hs.32949 defensin, beta 1 /FL=gb:NM_005218.2 gb:U73945.1 U73945 defensin, beta 1 DEFB1 1672 NM_005218 0002227 // innate immune response in mucosa // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0009617 // response to bacterium // inferred from direct assay /// 0009617 // response to bacterium // inferred from sequence or structural similarity /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 210398_x_at M98825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M98825.1 /DEF=Homo sapiens alpha-1,3 fucosyltransferase 6 (FCT3A) mRNA, complete cds. /FEA=mRNA /GEN=FCT3A /PROD=alpha-1,3 fucosyltransferase 6 /DB_XREF=gi:182491 /UG=Hs.32956 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) /FL=gb:M98825.1 gb:U27336.1 M98825 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) FUT6 2528 NM_000150 /// NM_001040701 /// XM_005259526 /// XM_005259527 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 210399_x_at U27336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27336.1 /DEF=Human alpha (1,3) fucosyltransferase (FUT6) mRNA, minor transcript II, complete cds. /FEA=mRNA /GEN=FUT6 /PROD=alpha (1,3) fucosyltransferase /DB_XREF=gi:967208 /UG=Hs.32956 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) /FL=gb:M98825.1 gb:U27336.1 U27336 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) FUT6 2528 NM_000150 /// NM_001040701 /// XM_005259526 /// XM_005259527 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 210400_at L76224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76224.1 /DEF=Homo sapiens NMDA receptor mRNA, complete cds. /FEA=mRNA /PROD=NMDA receptor /DB_XREF=gi:1196448 /UG=Hs.36451 glutamate receptor, ionotropic, N-methyl D-aspartate 2C /FL=gb:L76224.1 gb:U77782.1 gb:NM_000835.2 L76224 glutamate receptor, ionotropic, N-methyl D-aspartate 2C GRIN2C 2905 NM_000835 /// NM_001278553 /// NR_103735 /// XM_006721845 /// XM_006721846 /// XM_006721847 /// XM_006721848 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0033058 // directional locomotion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 210401_at U45448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U45448.1 /DEF=Human P2x1 receptor mRNA, complete cds. /FEA=mRNA /PROD=P2X1 receptor /DB_XREF=gi:1314356 /UG=Hs.41735 purinergic receptor P2X, ligand-gated ion channel, 1 /FL=gb:U45448.1 gb:AF020498.1 gb:NM_002558.1 U45448 purinergic receptor P2X, ligand-gated ion channel, 1 P2RX1 5023 NM_002558 /// XM_006721529 /// XR_243558 0002554 // serotonin secretion by platelet // inferred from electronic annotation /// 0003056 // regulation of vascular smooth muscle contraction // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from direct assay /// 0006812 // cation transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007320 // insemination // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from direct assay /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0043270 // positive regulation of ion transport // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005639 // integral component of nuclear inner membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031240 // external side of cell outer membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001614 // purinergic nucleotide receptor activity // inferred from direct assay /// 0004931 // extracellular ATP-gated cation channel activity // not recorded /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 210402_at U03884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03884.1 /DEF=Human inwardly rectifying K+ channel (ROMK1) mRNA, complete cds. /FEA=mRNA /GEN=ROMK1 /PROD=inwardly rectifying K+ channel /DB_XREF=gi:433142 /UG=Hs.463 potassium inwardly-rectifying channel, subfamily J, member 1 /FL=gb:U03884.1 gb:U12543.1 U03884 potassium inwardly-rectifying channel, subfamily J, member 1 KCNJ1 3758 NM_000220 /// NM_153764 /// NM_153765 /// NM_153766 /// NM_153767 0001822 // kidney development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007588 // excretion // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070294 // renal sodium ion absorption // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 1900128 // regulation of G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay 210403_s_at U12543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U12543.1 /DEF=Human ROM-K potassium channel protein isoform romk3 mRNA, complete cds. /FEA=mRNA /PROD=ROM-K potassium channel protein isoform romk3 /DB_XREF=gi:529316 /UG=Hs.463 potassium inwardly-rectifying channel, subfamily J, member 1 /FL=gb:U03884.1 gb:U12543.1 U12543 potassium inwardly-rectifying channel, subfamily J, member 1 KCNJ1 3758 NM_000220 /// NM_153764 /// NM_153765 /// NM_153766 /// NM_153767 0001822 // kidney development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007588 // excretion // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070294 // renal sodium ion absorption // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 1900128 // regulation of G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay 210404_x_at AF078803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078803.1 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase II beta subunit mRNA, complete cds. /FEA=mRNA /PROD=calciumcalmodulin-dependent protein kinase IIbeta subunit /DB_XREF=gi:5326756 /UG=Hs.4884 calciumcalmodulin-dependent protein kinase (CaM kinase) II beta /FL=gb:NM_001220.1 gb:AF112472.1 gb:AF078803.1 AF078803 calcium/calmodulin-dependent protein kinase II beta CAMK2B 816 NM_001220 /// NM_001293170 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 /// XM_005249859 /// XM_005249861 /// XM_005249862 /// XM_005249864 /// XM_006715776 /// XM_006715777 /// XM_006715778 /// XM_006715779 /// XM_006715780 /// XM_006715781 /// XM_006715782 /// XM_006715783 /// XM_006715784 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0002030 // inhibitory G-protein coupled receptor phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032222 // regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051823 // regulation of synapse structural plasticity // traceable author statement /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060466 // activation of meiosis involved in egg activation // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // traceable author statement /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210405_x_at AF153687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153687.1 /DEF=Homo sapiens Fas-like protein precusor mRNA, complete cds. /FEA=mRNA /PROD=Fas-like protein precusor /DB_XREF=gi:8489094 /UG=Hs.51233 tumor necrosis factor receptor superfamily, member 10b /FL=gb:AF012535.1 gb:AF012628.1 gb:AF018657.1 gb:AF020501.1 gb:AF022386.1 gb:AF016268.1 gb:NM_003842.1 gb:AF192548.1 gb:AF153687.1 AF153687 tumor necrosis factor receptor superfamily, member 10b TNFRSF10B 8795 NM_003842 /// NM_147187 /// NR_027140 /// XM_006716409 0006915 // apoptotic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045569 // TRAIL binding // non-traceable author statement 210406_s_at AL136727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136727.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566K144 (from clone DKFZp566K144); complete cds. /FEA=mRNA /GEN=DKFZp566K144 /PROD=hypothetical protein /DB_XREF=gi:12052972 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:AL136727.1 AL136727 RAB6A, member RAS oncogene family /// RAB6C, member RAS oncogene family /// RAB6C-like RAB6A /// RAB6C /// WTH3DI 5870 /// 84084 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_032144 /// NM_198896 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 210407_at AF070670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070670.1 /DEF=Homo sapiens protein phosphatase 2C alpha 2 mRNA, complete cds. /FEA=mRNA /PROD=protein phosphatase 2C alpha 2 /DB_XREF=gi:3372871 /UG=Hs.57764 protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform /FL=gb:AF070670.1 AF070670 protein phosphatase, Mg2+/Mn2+ dependent, 1A PPM1A 5494 NM_021003 /// NM_177951 /// NM_177952 /// XM_005267777 /// XM_005267778 /// XM_005267779 /// XM_005267780 /// XM_005267781 /// XM_006720179 /// XM_006720180 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from physical interaction 210408_s_at AB009288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009288.1 /DEF=Homo sapiens mRNA for N-copine, complete cds. /FEA=mRNA /PROD=N-copine /DB_XREF=gi:4520343 /UG=Hs.6132 copine VI (neuronal) /FL=gb:NM_006032.2 gb:AB009288.1 AB009288 copine VI (neuronal) CPNE6 9362 NM_001280558 /// NM_006032 /// XM_005268216 /// XM_005268217 0006629 // lipid metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210409_at AB016898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016898.1 /DEF=Homo sapiens HGC6.4 mRNA, complete cds. /FEA=mRNA /GEN=HGC6.4 /DB_XREF=gi:5006252 /UG=Hs.100469 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 /FL=gb:AB016898.1 AB016898 MLLT4 antisense RNA 1 (head to head) MLLT4-AS1 653483 NM_001042508 /// NR_027906 210410_s_at AF034759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF034759.1 /DEF=Homo sapiens MutS homolog (MSH5) mRNA, complete cds. /FEA=mRNA /GEN=MSH5 /PROD=MutS homolog /DB_XREF=gi:2653648 /UG=Hs.112193 mutS (E. coli) homolog 5 /FL=gb:BC001358.1 gb:BC002498.1 gb:AF034759.1 gb:AF048986.1 gb:AF070071.1 gb:NM_002441.1 AF034759 mutS homolog 5 /// MSH5-SAPCD1 readthrough (NMD candidate) /// suppressor APC domain containing 1 MSH5 /// MSH5-SAPCD1 /// SAPCD1 4439 /// 401251 /// 100532732 NM_001039651 /// NM_002441 /// NM_025259 /// NM_172165 /// NM_172166 /// NR_037846 0000710 // meiotic mismatch repair // not recorded /// 0006200 // ATP catabolic process // not recorded /// 0006298 // mismatch repair // traceable author statement /// 0007126 // meiotic nuclear division // traceable author statement /// 0007131 // reciprocal meiotic recombination // not recorded /// 0007136 // meiotic prophase II // traceable author statement /// 0045005 // maintenance of fidelity involved in DNA-dependent DNA replication // inferred from electronic annotation /// 0045143 // homologous chromosome segregation // not recorded /// 0045910 // negative regulation of DNA recombination // inferred from electronic annotation /// 0051026 // chiasma assembly // not recorded 0000795 // synaptonemal complex // not recorded /// 0032300 // mismatch repair complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030983 // mismatched DNA binding // not recorded 210411_s_at U90278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90278.1 /DEF=Human N-methyl-D-aspartate receptor 2B subunit precursor mRNA, complete cds. /FEA=mRNA /PROD=N-methyl-D-aspartate receptor 2B subunitprecursor /DB_XREF=gi:1899201 /UG=Hs.1198 glutamate receptor, ionotropic, N-methyl D-aspartate 2B /FL=gb:U90278.1 gb:U88963.1 gb:U11287.1 gb:NM_000834.2 U90278 glutamate receptor, ionotropic, N-methyl D-aspartate 2B GRIN2B 2904 NM_000834 /// XM_005253351 0001662 // behavioral fear response // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007423 // sensory organ development // inferred from electronic annotation /// 0007611 // learning or memory // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042596 // fear response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210412_at U11287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U11287.1 /DEF=Human N-methyl-D-aspartate receptor subunit NR3 (hNR3) mRNA, complete cds. /FEA=mRNA /GEN=hNR3 /PROD=N-methyl-D-aspartate receptor subunit NR3 /DB_XREF=gi:560546 /UG=Hs.1198 glutamate receptor, ionotropic, N-methyl D-aspartate 2B /FL=gb:U90278.1 gb:U88963.1 gb:U11287.1 gb:NM_000834.2 U11287 glutamate receptor, ionotropic, N-methyl D-aspartate 2B GRIN2B 2904 NM_000834 /// XM_005253351 0001662 // behavioral fear response // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007423 // sensory organ development // inferred from electronic annotation /// 0007611 // learning or memory // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042596 // fear response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210413_x_at U19557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19557.1 /DEF=Human squamous cell carcinoma antigen 2 (SCCA2) mRNA, complete cds. /FEA=mRNA /GEN=SCCA2 /PROD=squamous cell carcinoma antigen 2 /DB_XREF=gi:1052870 /UG=Hs.123035 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 /FL=gb:U19557.1 U19557 serpin peptidase inhibitor, clade B (ovalbumin), member 3 /// serpin peptidase inhibitor, clade B (ovalbumin), member 4 SERPINB3 /// SERPINB4 6317 /// 6318 NM_002974 /// NM_006919 0006955 // immune response // non-traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210414_at AF169675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF169675.1 /DEF=Homo sapiens leucine-rich repeat transmembrane protein FLRT1 (FLRT1) mRNA, complete cds. /FEA=mRNA /GEN=FLRT1 /PROD=leucine-rich repeat transmembrane protein FLRT1 /DB_XREF=gi:6808602 /UG=Hs.12523 fibronectin leucine rich transmembrane protein 1 /FL=gb:AF169675.1 gb:NM_013280.2 AF169675 fibronectin leucine rich transmembrane protein 1 FLRT1 23769 NM_013280 /// XM_005273861 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement 210415_s_at AF053970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053970.1 /DEF=Homo sapiens outer dense fiber protein 22 mRNA, complete cds. /FEA=mRNA /PROD=outer dense fiber protein 22 /DB_XREF=gi:2996005 /UG=Hs.129055 outer dense fibre of sperm tails 2 /FL=gb:AF053970.1 AF053970 outer dense fiber of sperm tails 2 ODF2 4957 NM_001242352 /// NM_001242353 /// NM_001242354 /// NM_002540 /// NM_153432 /// NM_153433 /// NM_153435 /// NM_153436 /// NM_153437 /// NM_153439 /// NM_153440 /// XM_005252010 /// XM_005252011 /// XM_005252012 /// XM_005252013 /// XM_005252014 /// XM_005252015 /// XM_005252016 /// XM_005252017 /// XM_005252018 /// XM_005252019 /// XM_005252020 /// XM_005252021 /// XM_005252022 /// XM_005252023 /// XM_005252024 /// XM_005252025 /// XM_005252026 /// XM_005252027 /// XM_005252028 /// XM_005252029 /// XM_005252030 /// XM_006717122 /// XM_006717123 /// XM_006717124 /// XM_006717125 /// XM_006717126 /// XM_006717127 /// XM_006717128 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0001520 // outer dense fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210416_s_at BC004207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004207.1 /DEF=Homo sapiens, protein kinase Chk2, clone MGC:4081, mRNA, complete cds. /FEA=mRNA /PROD=protein kinase Chk2 /DB_XREF=gi:13278893 /UG=Hs.146329 protein kinase Chk2 /FL=gb:BC004207.1 gb:AF086904.1 gb:AF096279.1 gb:AF174135.1 gb:NM_007194.1 BC004207 checkpoint kinase 2 CHEK2 11200 NM_001005735 /// NM_001257387 /// NM_007194 /// NM_145862 /// XM_006724114 /// XM_006724115 /// XM_006724116 /// XR_244350 0000077 // DNA damage checkpoint // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006975 // DNA damage induced protein phosphorylation // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042176 // regulation of protein catabolic process // inferred from mutant phenotype /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0072428 // signal transduction involved in intra-S DNA damage checkpoint // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype /// 0090399 // replicative senescence // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210417_s_at U81802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U81802.1 /DEF=Human PtdIns 4-kinase (PI4Kb) mRNA, complete cds. /FEA=mRNA /GEN=PI4Kb /PROD=PtdIns 4-kinase /DB_XREF=gi:1894946 /UG=Hs.154846 phosphatidylinositol 4-kinase, catalytic, beta polypeptide /FL=gb:U81802.1 U81802 phosphatidylinositol 4-kinase, catalytic, beta PI4KB 5298 NM_001198773 /// NM_001198774 /// NM_001198775 /// NM_002651 /// XM_005245261 /// XM_005245262 /// XM_005245263 /// XM_005245264 /// XM_005245265 /// XM_006711385 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 210418_s_at AF023265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF023265.1 /DEF=Homo sapiens NAD+-specific isocitrate dehydrogenase beta subunit isoform A mRNA, nuclear gene encoding mitochondrial product, complete cds. /FEA=mRNA /PROD=NAD+-specific isocitrate dehydrogenase betasubunit isoform A /DB_XREF=gi:4103445 /UG=Hs.155410 isocitrate dehydrogenase 3 (NAD+) beta /FL=gb:AF023265.1 AF023265 isocitrate dehydrogenase 3 (NAD+) beta IDH3B 3420 NM_001258384 /// NM_006899 /// NM_174855 /// NM_174856 /// XM_005260716 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210419_at AF031924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031924.1 /DEF=Homo sapiens homeobox transcription factor barx2 (BARX2) mRNA, complete cds. /FEA=mRNA /GEN=BARX2 /PROD=barx2 /DB_XREF=gi:2921294 /UG=Hs.167218 BarH-like homeobox 2 /FL=gb:AF031924.1 gb:NM_003658.2 AF031924 BARX homeobox 2 BARX2 8538 NM_003658 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0042637 // catagen // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210420_at AB014602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014602.1 /DEF=Homo sapiens mRNA for KIAA0702 protein, complete cds. /FEA=mRNA /GEN=KIAA0702 /PROD=KIAA0702 protein /DB_XREF=gi:3327217 /UG=Hs.173092 solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 1 /FL=gb:AB014602.1 AB014602 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 SLC24A1 9187 NM_001254740 /// NM_004727 /// XM_005254778 /// XM_005254779 /// XM_005254780 /// XM_005254781 /// XM_006720764 /// XM_006720765 /// XM_006720766 /// XM_006720767 /// XM_006720768 /// XM_006720769 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007601 // visual perception // non-traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009642 // response to light intensity // non-traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019867 // outer membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008273 // calcium, potassium:sodium antiporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 210421_s_at AB014602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014602.1 /DEF=Homo sapiens mRNA for KIAA0702 protein, complete cds. /FEA=mRNA /GEN=KIAA0702 /PROD=KIAA0702 protein /DB_XREF=gi:3327217 /UG=Hs.173092 solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 1 /FL=gb:AB014602.1 AB014602 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 SLC24A1 9187 NM_001254740 /// NM_004727 /// XM_005254778 /// XM_005254779 /// XM_005254780 /// XM_005254781 /// XM_006720764 /// XM_006720765 /// XM_006720766 /// XM_006720767 /// XM_006720768 /// XM_006720769 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007601 // visual perception // non-traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009642 // response to light intensity // non-traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019867 // outer membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008273 // calcium, potassium:sodium antiporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 210422_x_at D50402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50402.1 /DEF=Human mRNA for NRAMP1, complete cds. /FEA=mRNA /PROD=Nramp /DB_XREF=gi:1000996 /UG=Hs.182611 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 /FL=gb:D50402.1 gb:D50403.1 gb:NM_000578.1 gb:L32185.1 D50402 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 SLC11A1 6556 NM_000578 /// NM_001032220 /// XM_005246793 /// XM_005246794 /// XM_006712709 /// XM_006712710 /// XM_006712711 /// XR_427107 /// XR_427108 /// XR_427109 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0001818 // negative regulation of cytokine production // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002309 // T cell proliferation involved in immune response // inferred from sequence or structural similarity /// 0002369 // T cell cytokine production // inferred from sequence or structural similarity /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006876 // cellular cadmium ion homeostasis // inferred from genetic interaction /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0006909 // phagocytosis // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0015707 // nitrite transport // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032623 // interleukin-2 production // inferred from sequence or structural similarity /// 0032632 // interleukin-3 production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042116 // macrophage activation // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043091 // L-arginine import // inferred from sequence or structural similarity /// 0045342 // MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045730 // respiratory burst // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048002 // antigen processing and presentation of peptide antigen // inferred from sequence or structural similarity /// 0048255 // mRNA stabilization // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055072 // iron ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from sequence or structural similarity /// 0070574 // cadmium ion transmembrane transport // inferred from genetic interaction /// 0070839 // divalent metal ion export // inferred from sequence or structural similarity /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0031902 // late endosome membrane // traceable author statement /// 0070821 // tertiary granule membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046915 // transition metal ion transmembrane transporter activity // inferred from genetic interaction /// 0051139 // metal ion:proton antiporter activity // inferred from genetic interaction 210423_s_at L32185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L32185.1 /DEF=Homo sapiens integral membrane protein (NRAMP1) mRNA, complete cds. /FEA=mRNA /GEN=NRAMP1 /PROD=integral membrane protein /DB_XREF=gi:600219 /UG=Hs.182611 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 /FL=gb:D50402.1 gb:D50403.1 gb:NM_000578.1 gb:L32185.1 L32185 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 SLC11A1 6556 NM_000578 /// NM_001032220 /// XM_005246793 /// XM_005246794 /// XM_006712709 /// XM_006712710 /// XM_006712711 /// XR_427107 /// XR_427108 /// XR_427109 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0001818 // negative regulation of cytokine production // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002309 // T cell proliferation involved in immune response // inferred from sequence or structural similarity /// 0002369 // T cell cytokine production // inferred from sequence or structural similarity /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006876 // cellular cadmium ion homeostasis // inferred from genetic interaction /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0006909 // phagocytosis // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0015707 // nitrite transport // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032623 // interleukin-2 production // inferred from sequence or structural similarity /// 0032632 // interleukin-3 production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042116 // macrophage activation // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043091 // L-arginine import // inferred from sequence or structural similarity /// 0045342 // MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045730 // respiratory burst // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048002 // antigen processing and presentation of peptide antigen // inferred from sequence or structural similarity /// 0048255 // mRNA stabilization // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055072 // iron ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from sequence or structural similarity /// 0070574 // cadmium ion transmembrane transport // inferred from genetic interaction /// 0070839 // divalent metal ion export // inferred from sequence or structural similarity /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0031902 // late endosome membrane // traceable author statement /// 0070821 // tertiary granule membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046915 // transition metal ion transmembrane transporter activity // inferred from genetic interaction /// 0051139 // metal ion:proton antiporter activity // inferred from genetic interaction 210424_s_at AF163441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF163441.1 /DEF=Homo sapiens golgin 67 mRNA, complete cds. /FEA=mRNA /PROD=golgin 67 /DB_XREF=gi:6969979 /UG=Hs.182982 golgin-67 /FL=gb:AF163441.1 gb:AF164622.1 AF163441 golgin A8 family, member A /// golgin A8 family, member B /// uncharacterized LOC101930583 GOLGA8A /// GOLGA8B /// LOC101930583 23015 /// 440270 /// 101930583 NM_001023567 /// NM_181077 /// NR_027409 /// NR_027410 /// XM_005254389 /// XM_005254391 /// XM_006720440 /// XM_006720530 /// XR_248092 /// XR_248093 /// XR_248094 /// XR_248096 /// XR_424599 /// XR_424600 /// XR_424601 /// XR_424602 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 210425_x_at AF164622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF164622.1 /DEF=Homo sapiens golgin-67 (GOLGA5) mRNA, complete cds. /FEA=mRNA /GEN=GOLGA5 /PROD=golgin-67 /DB_XREF=gi:7211437 /UG=Hs.182982 golgin-67 /FL=gb:AF163441.1 gb:AF164622.1 AF164622 golgin A8 family, member A /// golgin A8 family, member B /// uncharacterized LOC101930583 GOLGA8A /// GOLGA8B /// LOC101930583 23015 /// 440270 /// 101930583 NM_001023567 /// NM_181077 /// NR_027409 /// NR_027410 /// XM_005254389 /// XM_005254391 /// XM_006720440 /// XM_006720530 /// XR_248092 /// XR_248093 /// XR_248094 /// XR_248096 /// XR_424599 /// XR_424600 /// XR_424601 /// XR_424602 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 210426_x_at U04897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04897.1 /DEF=Human orphan hormone nuclear receptor RORalpha1 mRNA, complete cds. /FEA=mRNA /PROD=RORalpha1 /DB_XREF=gi:451563 /UG=Hs.2156 RAR-related orphan receptor A /FL=gb:U04897.1 U04897 RAR-related orphan receptor A RORA 6095 NM_002943 /// NM_134260 /// NM_134261 /// NM_134262 /// XM_005254584 0001525 // angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from mutant phenotype /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0019218 // regulation of steroid metabolic process // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021930 // cerebellar granule cell precursor proliferation // inferred from sequence or structural similarity /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0036315 // cellular response to sterol // inferred from direct assay /// 0036315 // cellular response to sterol // inferred from mutant phenotype /// 0042692 // muscle cell differentiation // inferred from mutant phenotype /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from sequence or structural similarity /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072539 // T-helper 17 cell differentiation // inferred from sequence or structural similarity /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001222 // transcription corepressor binding // inferred from physical interaction /// 0001223 // transcription coactivator binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008142 // oxysterol binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0098531 // direct ligand regulated sequence-specific DNA binding transcription factor activity // inferred from direct assay 210427_x_at BC001388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001388.1 /DEF=Homo sapiens, annexin A2, clone MGC:2257, mRNA, complete cds. /FEA=mRNA /PROD=annexin A2 /DB_XREF=gi:12655074 /UG=Hs.217493 annexin A2 /FL=gb:BC001388.1 BC001388 annexin A2 ANXA2 302 NM_001002857 /// NM_001002858 /// NM_001136015 /// NM_004039 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210428_s_at AF260566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF260566.1 /DEF=Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate HRS isoform 2 (HRS) mRNA, complete cds. /FEA=mRNA /GEN=HRS /PROD=hepatocyte growth factor-regulated tyrosinekinase substrate HRS isoform 2 /DB_XREF=gi:9022388 /UG=Hs.24756 hepatocyte growth factor-regulated tyrosine kinase substrate /FL=gb:AF260566.1 AF260566 hepatocyte growth factor-regulated tyrosine kinase substrate HGS 9146 NM_004712 /// XM_005257794 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // non-traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210429_at X63097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63097.1 /DEF=H.sapiens mRNA for rhesus polypeptide (RhXIII). /FEA=mRNA /PROD=Rhesus polypeptide XIII /DB_XREF=gi:36046 /UG=Hs.283822 Rhesus blood group, D antigen /FL=gb:AB046420.1 gb:L08429.1 gb:AF037626.1 gb:AB018966.1 gb:AB018967.1 gb:AB018968.1 gb:AB018969.1 gb:AF177938.1 gb:AF187846.1 gb:AB037270.1 gb:NM_016225.1 gb:NM_016124.1 X63097 Rh blood group, D antigen RHD 6007 NM_001127691 /// NM_001282867 /// NM_001282868 /// NM_001282869 /// NM_001282870 /// NM_001282871 /// NM_001282872 /// NM_016124 /// NM_016225 0015696 // ammonium transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from electronic annotation 210430_x_at L08429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L08429.1 /DEF=Human RhD blood group antigen mRNA, complete cds. /FEA=mRNA /PROD=RhD blood group antigen /DB_XREF=gi:337390 /UG=Hs.283822 Rhesus blood group, D antigen /FL=gb:AB046420.1 gb:L08429.1 gb:AF037626.1 gb:AB018966.1 gb:AB018967.1 gb:AB018968.1 gb:AB018969.1 gb:AF177938.1 gb:AF187846.1 gb:AB037270.1 gb:NM_016225.1 gb:NM_016124.1 L08429 Rh blood group, D antigen RHD 6007 NM_001127691 /// NM_001282867 /// NM_001282868 /// NM_001282869 /// NM_001282870 /// NM_001282871 /// NM_001282872 /// NM_016124 /// NM_016225 0015696 // ammonium transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from electronic annotation 210431_at J04948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04948.1 /DEF=Human alkaline phosphatase (ALP-1) mRNA, complete cds. /FEA=mRNA /GEN=ALPP /DB_XREF=gi:178418 /UG=Hs.284255 alkaline phosphatase, placental (Regan isozyme) /FL=gb:J04948.1 J04948 alkaline phosphatase, placental-like 2 ALPPL2 251 NM_031313 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210432_s_at AF225986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225986.1 /DEF=Homo sapiens voltage-gated sodium channel alpha subunit splice variant SCN3A-s (SCN3A) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=SCN3A /PROD=voltage-gated sodium channel alpha subunitsplice variant SCN3A-s /DB_XREF=gi:12642271 /UG=Hs.300717 sodium channel, voltage-gated, type III, alpha polypeptide /FL=gb:AF225986.1 AF225986 sodium channel, voltage-gated, type III, alpha subunit SCN3A 6328 NM_001081676 /// NM_001081677 /// NM_006922 /// XM_006712679 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0019228 // neuronal action potential // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // non-traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210433_at BC000582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000582.1 /DEF=Homo sapiens, Similar to KIAA0180 protein, clone MGC:2482, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0180 protein /DB_XREF=gi:12653608 /UG=Hs.307001 Homo sapiens, Similar to KIAA0180 protein, clone MGC:2482, mRNA, complete cds /FL=gb:BC000582.1 BC000582 protein O-fucosyltransferase 1 POFUT1 23509 NM_015352 /// NM_172236 /// XR_430297 0001525 // angiogenesis // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0036066 // protein O-linked fucosylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046922 // peptide-O-fucosyltransferase activity // inferred from direct assay /// 0046922 // peptide-O-fucosyltransferase activity // traceable author statement 210434_x_at AF151056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151056.1 /DEF=Homo sapiens HSPC222 mRNA, complete cds. /FEA=mRNA /PROD=HSPC222 /DB_XREF=gi:7106833 /UG=Hs.323093 Homo sapiens, jumping translocation breakpoint, clone MGC:10274, mRNA, complete cds /FL=gb:AF151056.1 AF151056 jumping translocation breakpoint JTB 10899 NM_006694 0000910 // cytokinesis // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0019901 // protein kinase binding // inferred from direct assay 210435_at BC000924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000924.2 /DEF=Homo sapiens, Similar to NBR2, clone MGC:5031, mRNA, complete cds. /FEA=mRNA /PROD=Similar to NBR2 /DB_XREF=gi:12803009 /UG=Hs.324050 Homo sapiens, Similar to NBR2, clone MGC:5031, mRNA, complete cds /FL=gb:BC000924.2 BC000924 ADP-ribosylation factor-like 17A /// ADP-ribosylation factor-like 17B ARL17A /// ARL17B 51326 /// 100506084 NM_001039083 /// NM_001103154 /// NM_001113738 /// NM_001288811 /// NM_001288812 /// NM_001288813 /// NM_016632 /// NR_003653 /// XM_005256917 /// XM_005256918 /// XM_005257439 /// XM_005257440 /// XM_005257441 /// XM_006725627 /// XM_006725628 /// XM_006725629 /// XM_006725630 /// XR_429866 /// XR_429895 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 210436_at BC005220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005220.1 /DEF=Homo sapiens, Similar to chaperonin containing TCP1, subunit 8 (theta), clone MGC:12240, mRNA, complete cds. /FEA=mRNA /PROD=Similar to chaperonin containing TCP1, subunit 8(theta) /DB_XREF=gi:13528842 /UG=Hs.332008 Homo sapiens, Similar to chaperonin containing TCP1, subunit 8 (theta), clone MGC:12240, mRNA, complete cds /FL=gb:BC005220.1 BC005220 chaperonin containing TCP1, subunit 8 (theta) CCT8 10694 NM_001282907 /// NM_001282908 /// NM_001282909 /// NM_006585 0006200 // ATP catabolic process // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 210437_at BC002351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002351.1 /DEF=Homo sapiens, melanoma antigen, family A, 9, clone MGC:8421, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 9 /DB_XREF=gi:12803094 /UG=Hs.37110 melanoma antigen, family A, 9 /FL=gb:BC002351.1 gb:NM_005365.1 BC002351 melanoma antigen family A, 9 /// melanoma antigen family A, 9B MAGEA9 /// MAGEA9B 4108 /// 728269 NM_001080790 /// NM_005365 /// XM_005262334 /// XM_005262335 /// XM_005262336 /// XM_005278192 /// XM_005278193 /// XM_005278194 210438_x_at M25077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M25077.1 /DEF=Human SS-ARo ribonucleoprotein autoantigen 60 kd subunit mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:387656 /UG=Hs.554 Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) /FL=gb:M25077.1 M25077 TROVE domain family, member 2 TROVE2 6738 NM_001042369 /// NM_001042370 /// NM_001173524 /// NM_001173525 /// NM_004600 /// NR_033393 /// XM_006711495 /// XM_006711496 /// XM_006711497 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210439_at AB023135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB023135.1 /DEF=Homo sapiens mRNA for activation-inducible lymphocyte immunomediatory molecule AILIM, complete cds. /FEA=mRNA /PROD=activation-inducible lymphocyte immunomediatorymolecule AILIM /DB_XREF=gi:5360718 /UG=Hs.56247 inducible T-cell co-stimulator /FL=gb:AB023135.1 AB023135 inducible T-cell co-stimulator ICOS 29851 NM_012092 /// XM_005246482 0002517 // T cell tolerance induction // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 210440_s_at AF064102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064102.1 /DEF=Homo sapiens Cdc14A2 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14A2 phosphatase /DB_XREF=gi:3136327 /UG=Hs.65993 CDC14 (cell division cycle 14, S. cerevisiae) homolog A /FL=gb:AF064102.1 AF064102 cell division cycle 14A CDC14A 8556 NM_003672 /// NM_033312 /// NM_033313 /// XM_005271294 /// XM_005271296 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 210441_at AF064102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064102.1 /DEF=Homo sapiens Cdc14A2 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14A2 phosphatase /DB_XREF=gi:3136327 /UG=Hs.65993 CDC14 (cell division cycle 14, S. cerevisiae) homolog A /FL=gb:AF064102.1 AF064102 cell division cycle 14A CDC14A 8556 NM_003672 /// NM_033312 /// NM_033313 /// XM_005271294 /// XM_005271296 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 210442_at AB012701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012701.2 /DEF=Homo sapiens mRNA for ST2L, 5 noncoding region including distal exon (exon 1a), complete cds. /FEA=mRNA /GEN=st2 /PROD=ST2L /DB_XREF=gi:6714554 /UG=Hs.66 interleukin 1 receptor-like 1 /FL=gb:NM_016232.2 gb:AB012701.2 AB012701 interleukin 1 receptor-like 1 IL1RL1 9173 NM_001282408 /// NM_003856 /// NM_016232 /// NM_173459 /// NR_104167 /// XM_006712839 0002826 // negative regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032754 // positive regulation of interleukin-5 production // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0038172 // interleukin-33-mediated signaling pathway // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002113 // interleukin-33 binding // inferred from electronic annotation /// 0002114 // interleukin-33 receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210443_x_at AF172452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF172452.1 /DEF=Homo sapiens opioid growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=opioid growth factor receptor /DB_XREF=gi:7595304 /UG=Hs.67896 7-60 protein /FL=gb:AF172452.1 AF172452 opioid growth factor receptor OGFR 11054 NM_007346 0001558 // regulation of cell growth // non-traceable author statement /// 0038003 // opioid receptor signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // non-traceable author statement 210444_at U59431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59431.1 /DEF=Human truncated pancreatic polypeptide receptor PP2 mRNA, complete cds. /FEA=mRNA /PROD=truncated pancreatic polypeptide receptor PP2 /DB_XREF=gi:1679631 /UG=Hs.73086 neuropeptide Y receptor Y6 (pseudogene) /FL=gb:U59431.1 gb:D86519.1 gb:U67780.1 gb:NM_006173.1 U59431 neuropeptide Y receptor Y6 (pseudogene) NPY6R 4888 NR_002713 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // not recorded /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // not recorded 210445_at U19869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19869.1 /DEF=Homo sapiens fatty acid binding protein 6 (FABP6) mRNA, complete cds. /FEA=mRNA /GEN=FABP6 /PROD=fatty acid binding protein 6 /DB_XREF=gi:894182 /UG=Hs.74126 fatty acid binding protein 6, ileal (gastrotropin) /FL=gb:NM_001445.1 gb:U19869.1 U19869 fatty acid binding protein 6, ileal FABP6 2172 NM_001040442 /// NM_001130958 /// NM_001445 /// XM_006714828 /// XM_006714829 /// XM_006714830 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 210446_at M30601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30601.1 /DEF=Human erythroid DNA-binding protein (GF-1) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183071 /UG=Hs.765 GATA-binding protein 1 (globin transcription factor 1) /FL=gb:M30601.1 gb:NM_002049.1 M30601 GATA binding protein 1 (globin transcription factor 1) GATA1 2623 NM_002049 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from mutant phenotype /// 0010724 // regulation of definitive erythrocyte differentiation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030219 // megakaryocyte differentiation // inferred from mutant phenotype /// 0030220 // platelet formation // inferred from mutant phenotype /// 0030221 // basophil differentiation // inferred from expression pattern /// 0030222 // eosinophil differentiation // inferred from expression pattern /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0033690 // positive regulation of osteoblast proliferation // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035854 // eosinophil fate commitment // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048468 // cell development // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071733 // transcriptional activation by promoter-enhancer looping // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 210447_at BC005111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005111.1 /DEF=Homo sapiens, clone MGC:13241, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13241) /DB_XREF=gi:13477274 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:BC005111.1 BC005111 glutamate dehydrogenase 2 GLUD2 2747 NM_012084 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay 210448_s_at U49396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49396.1 /DEF=Human ionotropic ATP receptor P2X5b mRNA, complete cds. /FEA=mRNA /PROD=P2X5b /DB_XREF=gi:1552523 /UG=Hs.77807 purinergic receptor P2X, ligand-gated ion channel, 5 /FL=gb:U49396.1 gb:AF070573.1 U49396 purinergic receptor P2X, ligand-gated ion channel, 5 P2RX5 5026 NM_001204519 /// NM_001204520 /// NM_002561 /// NM_175080 /// NM_175081 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement 0005639 // integral component of nuclear inner membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // traceable author statement /// 0005524 // ATP binding // non-traceable author statement 210449_x_at AF100544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100544.1 /DEF=Homo sapiens stress-activated protein kinase 2a (CSBP) mRNA, complete cds. /FEA=mRNA /GEN=CSBP /PROD=stress-activated protein kinase 2a /DB_XREF=gi:7109716 /UG=Hs.79107 mitogen-activated protein kinase 14 /FL=gb:BC000092.1 gb:L35264.1 gb:AF100544.1 AF100544 mitogen-activated protein kinase 14 MAPK14 1432 NM_001315 /// NM_139012 /// NM_139013 /// NM_139014 /// XM_006714998 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038066 // p38MAPK cascade // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090400 // stress-induced premature senescence // inferred from mutant phenotype /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005623 // cell // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity 210450_at BC002792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002792.1 /DEF=Homo sapiens, clone MGC:3963, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3963) /DB_XREF=gi:12803890 /UG=Hs.81221 Human L2-9 transcript of unrearranged immunoglobulin V(H)5 pseudogene /FL=gb:BC002792.1 BC002792 immunoglobulin heavy variable 5-78 (pseudogene) IGHV5-78 28387 210451_at M15465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15465.1 /DEF=Human pyruvate kinase type L mRNA, complete cds. /FEA=mRNA /GEN=PKLR /PROD=pyruvate kinase /DB_XREF=gi:189995 /UG=Hs.95990 pyruvate kinase, liver and RBC /FL=gb:M15465.1 M15465 pyruvate kinase, liver and RBC PKLR 5313 NM_000298 /// NM_181871 /// XM_005245266 /// XM_006711386 /// XM_006726212 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210452_x_at D26480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D26480.1 /DEF=Human mRNA for leukotriene B4 omega-hydroxylase, complete cds. /FEA=mRNA /PROD=leukotriene B4 omega-hydroxylase /DB_XREF=gi:529642 /UG=Hs.101 cytochrome P450, subfamily IVF, polypeptide 2 /FL=gb:NM_001082.3 gb:D26480.1 gb:U02388.2 D26480 cytochrome P450, family 4, subfamily F, polypeptide 2 CYP4F2 8529 NM_001082 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0003091 // renal water homeostasis // inferred from expression pattern /// 0003095 // pressure natriuresis // inferred from expression pattern /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from mutant phenotype /// 0032304 // negative regulation of icosanoid secretion // inferred from mutant phenotype /// 0032305 // positive regulation of icosanoid secretion // inferred from mutant phenotype /// 0036101 // leukotriene B4 catabolic process // inferred from direct assay /// 0042360 // vitamin E metabolic process // inferred from direct assay /// 0042371 // vitamin K biosynthetic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047057 // vitamin-K-epoxide reductase (warfarin-sensitive) activity // inferred from mutant phenotype /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from direct assay /// 0052869 // arachidonic acid omega-hydroxylase activity // inferred from direct assay /// 0052870 // tocopherol omega-hydroxylase activity // inferred from electronic annotation /// 0052871 // alpha-tocopherol omega-hydroxylase activity // inferred from direct assay /// 0052872 // tocotrienol omega-hydroxylase activity // inferred from direct assay 210453_x_at AL050277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL050277.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566G013 (from clone DKFZp566G013); complete cds. /FEA=mRNA /GEN=DKFZp566G013 /PROD=hypothetical protein /DB_XREF=gi:4886454 /UG=Hs.107476 ATP synthase, H+ transporting, mitochondrial F1F0, subunit g /FL=gb:AL050277.1 AL050277 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G ATP5L 10632 NM_006476 /// NR_033759 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 210454_s_at U24660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24660.1 /DEF=Human G protein coupled inward rectifier potassium channel 2 (hiGIRK2) mRNA, complete cds. /FEA=mRNA /GEN=hiGIRK2 /DB_XREF=gi:1052874 /UG=Hs.11173 potassium inwardly-rectifying channel, subfamily J, member 6 /FL=gb:U24660.1 gb:U52153.1 gb:D87327.1 gb:NM_002240.1 U24660 potassium inwardly-rectifying channel, subfamily J, member 6 KCNJ6 3763 NM_002240 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // inferred from electronic annotation 210455_at AF050198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF050198.1 /DEF=Homo sapiens putative mitochondrial space protein 32.1 mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=putative mitochondrial space protein 32.1 /DB_XREF=gi:2961554 /UG=Hs.129730 putative mitochondrial space protein 32.1 /FL=gb:AF050198.1 AF050198 R3H domain and coiled-coil containing 1-like R3HCC1L 27291 NM_001256619 /// NM_001256620 /// NM_001256621 /// NM_014472 /// NM_138469 /// XM_006717768 /// XM_006717769 0035145 // exon-exon junction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 210456_at AF148464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF148464.1 /DEF=Homo sapiens CTP:phosphocholine cytidylyltransferase CCTB2 isoform (PCYT1B) mRNA, complete cds. /FEA=mRNA /GEN=PCYT1B /PROD=CTP:phosphocholine cytidylyltransferase CCTB2isoform /DB_XREF=gi:4973428 /UG=Hs.132794 phosphate cytidylyltransferase 1, choline, beta isoform /FL=gb:AF148464.1 AF148464 phosphate cytidylyltransferase 1, choline, beta PCYT1B 9468 NM_001163264 /// NM_001163265 /// NM_004845 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 210457_x_at AF176039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF176039.1 /DEF=Homo sapiens high mobility group protein-R mRNA, complete cds. /FEA=mRNA /PROD=high mobility group protein-R /DB_XREF=gi:5834272 /UG=Hs.139800 high-mobility group (nonhistone chromosomal) protein isoforms I and Y /FL=gb:AF176039.1 AF176039 high mobility group AT-hook 1 HMGA1 3159 NM_002131 /// NM_145899 /// NM_145901 /// NM_145902 /// NM_145903 /// NM_145904 /// NM_145905 /// XM_005249061 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // non-traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from expression pattern /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031936 // negative regulation of chromatin silencing // traceable author statement /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0075713 // establishment of integrated proviral latency // traceable author statement /// 0090402 // oncogene-induced cell senescence // inferred from direct assay /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003680 // AT DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0042975 // peroxisome proliferator activated receptor binding // inferred from direct assay /// 0046965 // retinoid X receptor binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from direct assay 210458_s_at BC003388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003388.1 /DEF=Homo sapiens, Similar to TRAF family member-associated NFKB activator, clone MGC:5046, mRNA, complete cds. /FEA=mRNA /PROD=Similar to TRAF family member-associated NFKBactivator /DB_XREF=gi:13097263 /UG=Hs.146847 TRAF family member-associated NFKB activator /FL=gb:BC003388.1 BC003388 TRAF family member-associated NFKB activator TANK 10010 NM_001199135 /// NM_004180 /// NM_133484 /// XM_005246206 /// XM_005246207 /// XM_005246208 /// XM_005246210 /// XM_005246211 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210459_at AB033605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB033605.1 /DEF=Homo sapiens mRNA for pUb-R5, complete cds. /FEA=mRNA /GEN=hpUb-R5 /PROD=pUb-R5 /DB_XREF=gi:8918352 /UG=Hs.148495 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 /FL=gb:AB033605.1 AB033605 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 PSMD4 5710 NM_002810 /// NM_153822 /// XM_005245354 /// XM_006711464 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210460_s_at AB033605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB033605.1 /DEF=Homo sapiens mRNA for pUb-R5, complete cds. /FEA=mRNA /GEN=hpUb-R5 /PROD=pUb-R5 /DB_XREF=gi:8918352 /UG=Hs.148495 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 /FL=gb:AB033605.1 AB033605 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 PSMD4 5710 NM_002810 /// NM_153822 /// XM_005245354 /// XM_006711464 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210461_s_at BC002448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002448.1 /DEF=Homo sapiens, Similar to actin binding LIM protein 1, clone MGC:1224, mRNA, complete cds. /FEA=mRNA /PROD=Similar to actin binding LIM protein 1 /DB_XREF=gi:12803266 /UG=Hs.158203 actin binding LIM protein 1 /FL=gb:BC002448.1 BC002448 actin binding LIM protein 1 ABLIM1 3983 NM_001003407 /// NM_001003408 /// NM_002313 /// NM_006720 /// XM_005269818 /// XM_005269819 /// XM_005269820 /// XM_005269821 /// XM_005269822 /// XM_005269823 /// XM_005269824 /// XM_005269825 /// XM_005269826 /// XM_005269827 /// XM_005269828 /// XM_005269830 /// XM_006717837 /// XM_006717838 /// XM_006717839 /// XM_006717840 /// XM_006717841 /// XM_006717842 /// XM_006717843 /// XM_006717844 /// XM_006717845 /// XM_006717846 /// XM_006717847 /// XM_006717848 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210462_at AF288161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288161.1 /DEF=Homo sapiens JEM-1short protein (BLZF1) mRNA, complete cds. /FEA=mRNA /GEN=BLZF1 /PROD=JEM-1short protein /DB_XREF=gi:11545418 /UG=Hs.158205 basic leucine zipper nuclear factor 1 (JEM-1) /FL=gb:AF288161.1 AF288161 basic leucine zipper nuclear factor 1 BLZF1 8548 NM_003666 /// XM_005245561 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 210463_x_at BC002492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002492.1 /DEF=Homo sapiens, hypothetical protein FLJ20244, clone MGC:1066, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20244 /DB_XREF=gi:12803346 /UG=Hs.158947 hypothetical protein FLJ20244 /FL=gb:BC002492.1 BC002492 tRNA methyltransferase 1 homolog (S. cerevisiae) TRMT1 55621 NM_001136035 /// NM_001142554 /// NM_017722 /// XM_005259983 /// XM_006722793 /// XM_006722794 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004809 // tRNA (guanine-N2-)-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210464_at AL080200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL080200.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F122 (from clone DKFZp434F122); complete cds. /FEA=mRNA /GEN=DKFZp434F122 /PROD=hypothetical protein /DB_XREF=gi:5262683 /UG=Hs.159352 DKFZP434F122 protein /FL=gb:AL080200.1 AL080200 long intergenic non-protein coding RNA 588 LINC00588 26138 NM_015643 /// NR_026772 210465_s_at U71300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71300.1 /DEF=Human snRNA activating protein complex 50kD subunit (SNAP50) mRNA, complete cds. /FEA=mRNA /GEN=SNAP50 /PROD=snRNA activating protein complex 50kD subunit /DB_XREF=gi:1619945 /UG=Hs.164915 small nuclear RNA activating complex, polypeptide 3, 50kD /FL=gb:U71300.1 U71300 small nuclear RNA activating complex, polypeptide 3, 50kDa SNAPC3 6619 NM_001039697 /// NM_003084 /// XR_428427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 210466_s_at BC002488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002488.1 /DEF=Homo sapiens, Similar to DKFZP564M2423 protein, clone MGC:1357, mRNA, complete cds. /FEA=mRNA /PROD=Similar to DKFZP564M2423 protein /DB_XREF=gi:12803338 /UG=Hs.165998 PAI-1 mRNA-binding protein /FL=gb:BC002488.1 BC002488 SERPINE1 mRNA binding protein 1 SERBP1 26135 NM_001018067 /// NM_001018068 /// NM_001018069 /// NM_015640 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210467_x_at BC003408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003408.1 /DEF=Homo sapiens, melanoma antigen, family A, 12, clone MGC:4914, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 12 /DB_XREF=gi:13097311 /UG=Hs.169246 melanoma antigen, family A, 12 /FL=gb:BC003408.1 gb:NM_005367.1 BC003408 melanoma antigen family A, 12 MAGEA12 4111 NM_001166386 /// NM_001166387 /// NM_005367 210469_at BC002915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002915.1 /DEF=Homo sapiens, Similar to discs, large (Drosophila) homolog 5, clone MGC:10415, mRNA, complete cds. /FEA=mRNA /PROD=Similar to discs, large (Drosophila) homolog 5 /DB_XREF=gi:12804124 /UG=Hs.170290 discs, large (Drosophila) homolog 5 /FL=gb:BC002915.1 BC002915 discs, large homolog 5 (Drosophila) DLG5 9231 NM_004747 /// XM_005270276 /// XM_006718055 /// XM_006718056 /// XM_006718057 /// XM_006725120 /// XM_006725121 /// XM_006725122 /// XM_006725123 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 210470_x_at BC003129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003129.1 /DEF=Homo sapiens, non-POU-domain-containing, octamer-binding, clone MGC:3380, mRNA, complete cds. /FEA=mRNA /PROD=non-POU-domain-containing, octamer-binding /DB_XREF=gi:13111916 /UG=Hs.172207 non-POU-domain-containing, octamer-binding /FL=gb:BC003129.1 BC003129 non-POU domain containing, octamer-binding NONO 4841 NM_001145408 /// NM_001145409 /// NM_001145410 /// NM_007363 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210471_s_at U33428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U33428.1 /DEF=Human K+ channel beta 1a subunit mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=K+ channel beta 1a subunit /DB_XREF=gi:995758 /UG=Hs.172471 potassium voltage-gated channel, shaker-related subfamily, beta member 1 /FL=gb:U33428.1 U33428 potassium voltage-gated channel, shaker-related subfamily, beta member 1 KCNAB1 7881 NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 210472_at BC005311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005311.1 /DEF=Homo sapiens, clone MGC:12386, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12386) /DB_XREF=gi:13529052 /UG=Hs.173451 metallothionein 1G /FL=gb:BC005311.1 BC005311 metallothionein 1G MT1G 4495 NM_005950 0030224 // monocyte differentiation // non-traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from expression pattern /// 0042117 // monocyte activation // non-traceable author statement /// 0045926 // negative regulation of growth // inferred from direct assay /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071280 // cellular response to copper ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from direct assay /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210473_s_at M37712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M37712.1 /DEF=Human p58GTA (galactosyltransferase associated protein kinase) mRNA, complete cds. /FEA=mRNA /PROD=p58GTA protein kinase /DB_XREF=gi:189480 /UG=Hs.183418 cell division cycle 2-like 1 (PITSLRE proteins) /FL=gb:M37712.1 gb:U04819.1 M37712 G protein-coupled receptor 125 GPR125 166647 NM_145290 /// XM_005248137 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210474_s_at U04819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04819.1 /DEF=Human protein kinase PITSLRE beta 1 mRNA, complete cds. /FEA=mRNA /PROD=PITSLRE beta 1 /DB_XREF=gi:507165 /UG=Hs.183418 cell division cycle 2-like 1 (PITSLRE proteins) /FL=gb:M37712.1 gb:U04819.1 U04819 cyclin-dependent kinase 11A /// cyclin-dependent kinase 11B CDK11A /// CDK11B 984 /// 728642 NM_001291345 /// NM_001787 /// NM_024011 /// NM_033486 /// NM_033487 /// NM_033488 /// NM_033489 /// NM_033490 /// NM_033492 /// NM_033493 /// NM_033527 /// NM_033529 /// NM_033532 /// NM_033534 /// XM_006711061 /// XM_006711062 /// XM_006711063 /// XM_006711064 /// XM_006711065 /// XM_006711066 /// XM_006711067 /// XM_006711068 /// XM_006711069 /// XM_006711070 /// XM_006711071 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210475_at L26494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L26494.1 /DEF=Homo sapiens (oct-6) mRNA, complete cds. /FEA=mRNA /GEN=oct-6 /DB_XREF=gi:508989 /UG=Hs.1837 POU domain, class 3, transcription factor 1 /FL=gb:L26494.1 L26494 POU class 3 homeobox 1 POU3F1 5453 NM_002699 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008366 // axon ensheathment // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 210476_s_at AF166329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF166329.1 /DEF=Homo sapiens intermediate prolactin receptor isoform mRNA, complete cds. /FEA=mRNA /PROD=intermediate prolactin receptor isoform /DB_XREF=gi:5734139 /UG=Hs.1906 prolactin receptor /FL=gb:AF166329.1 AF166329 prolactin receptor PRLR 5618 NM_000949 /// NM_001204314 /// NM_001204315 /// NM_001204316 /// NM_001204317 /// NM_001204318 /// NR_037910 /// XM_006714484 0006694 // steroid biosynthetic process // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007566 // embryo implantation // traceable author statement /// 0007595 // lactation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // non-traceable author statement /// 0038161 // prolactin signaling pathway // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042977 // activation of JAK2 kinase activity // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004925 // prolactin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042978 // ornithine decarboxylase activator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210477_x_at U34822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34822.1 /DEF=Human JNK1 alpha2 protein kinase (JNK1A2) mRNA, complete cds. /FEA=mRNA /GEN=JNK1A2 /PROD=JNK1 alpha2 protein kinase /DB_XREF=gi:1463130 /UG=Hs.190913 mitogen-activated protein kinase 8 /FL=gb:U34822.1 gb:NM_002750.1 gb:L26318.1 U34822 mitogen-activated protein kinase 8 MAPK8 5599 NM_001278547 /// NM_001278548 /// NM_002750 /// NM_139046 /// NM_139049 /// XM_006717917 /// XM_006717918 /// XM_006717919 0000165 // MAPK cascade // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from direct assay /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0031063 // regulation of histone deacetylation // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090045 // positive regulation of deacetylase activity // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000017 // positive regulation of determination of dorsal identity // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004705 // JUN kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035033 // histone deacetylase regulator activity // inferred from mutant phenotype /// 0042826 // histone deacetylase binding // inferred from physical interaction 210479_s_at L14611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14611.1 /DEF=Human transcription factor RZR-alpha mRNA, complete cds. /FEA=mRNA /PROD=transcription factor /DB_XREF=gi:348240 /UG=Hs.2156 RAR-related orphan receptor A /FL=gb:L14611.1 gb:NM_002943.1 gb:U04899.1 L14611 RAR-related orphan receptor A RORA 6095 NM_002943 /// NM_134260 /// NM_134261 /// NM_134262 /// XM_005254584 0001525 // angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from mutant phenotype /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0019218 // regulation of steroid metabolic process // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021930 // cerebellar granule cell precursor proliferation // inferred from sequence or structural similarity /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0036315 // cellular response to sterol // inferred from direct assay /// 0036315 // cellular response to sterol // inferred from mutant phenotype /// 0042692 // muscle cell differentiation // inferred from mutant phenotype /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from sequence or structural similarity /// 0070328 // triglyceride homeostasis // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072539 // T-helper 17 cell differentiation // inferred from sequence or structural similarity /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001222 // transcription corepressor binding // inferred from physical interaction /// 0001223 // transcription coactivator binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008142 // oxysterol binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0098531 // direct ligand regulated sequence-specific DNA binding transcription factor activity // inferred from direct assay 210480_s_at U90236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90236.2 /DEF=Homo sapiens myosin VI (MYO6) mRNA, complete cds. /FEA=mRNA /GEN=MYO6 /PROD=myosin VI /DB_XREF=gi:9280815 /UG=Hs.22564 myosin VI /FL=gb:U90236.2 U90236 myosin VI MYO6 4646 NM_004999 /// XM_005248719 /// XM_005248720 /// XM_005248721 /// XM_005248722 /// XM_005248724 /// XM_005248725 /// XM_005248726 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051046 // regulation of secretion // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060001 // minus-end directed microfilament motor activity // non-traceable author statement 210481_s_at AF245219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF245219.2 /DEF=Homo sapiens probable mannose binding C-type lectin DC-SIGNR mRNA, complete cds. /FEA=mRNA /PROD=probable mannose binding C-type lectin DC-SIGNR /DB_XREF=gi:12084796 /UG=Hs.23759 CD209 antigen-like /FL=gb:AF245219.2 AF245219 C-type lectin domain family 4, member M CLEC4M 10332 NM_001144904 /// NM_001144905 /// NM_001144906 /// NM_001144907 /// NM_001144908 /// NM_001144909 /// NM_001144910 /// NM_001144911 /// NM_014257 /// NM_214675 /// NM_214676 /// NR_026707 /// NR_026708 /// NR_026709 /// XM_006722611 /// XM_006722612 /// XM_006722613 /// XM_006722614 /// XM_006722615 /// XR_430125 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0009988 // cell-cell recognition // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019062 // virion attachment to host cell // traceable author statement /// 0019079 // viral genome replication // non-traceable author statement /// 0019882 // antigen processing and presentation // non-traceable author statement /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0046968 // peptide antigen transport // non-traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005537 // mannose binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0030369 // ICAM-3 receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046790 // virion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210482_x_at U71087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71087.1 /DEF=Human MAP kinase kinase MEK5b mRNA, complete cds. /FEA=mRNA /PROD=MAP kinase kinase MEK5b /DB_XREF=gi:1616778 /UG=Hs.250870 mitogen-activated protein kinase kinase 5 /FL=gb:U71087.1 U71087 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210483_at BC005043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005043.1 /DEF=Homo sapiens, Similar to tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain, clone MGC:12787, mRNA, complete cds. /FEA=mRNA /PROD=Similar to tumor necrosis factor receptorsuperfamily, member 10c, decoy without an intracellulardomain /DB_XREF=gi:13477162 /UG=Hs.253829 Homo sapiens, Similar to tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain, clone MGC:12787, mRNA, complete cds /FL=gb:BC005043.1 BC005043 uncharacterized LOC254896 /// tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain LOC254896 /// TNFRSF10C 8794 /// 254896 NM_003841 /// NR_046173 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0045569 // TRAIL binding // inferred from electronic annotation 210484_s_at BC005043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005043.1 /DEF=Homo sapiens, Similar to tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain, clone MGC:12787, mRNA, complete cds. /FEA=mRNA /PROD=Similar to tumor necrosis factor receptorsuperfamily, member 10c, decoy without an intracellulardomain /DB_XREF=gi:13477162 /UG=Hs.253829 Homo sapiens, Similar to tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain, clone MGC:12787, mRNA, complete cds /FL=gb:BC005043.1 BC005043 uncharacterized LOC254896 /// tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain LOC254896 /// TNFRSF10C 8794 /// 254896 NM_003841 /// NR_046173 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045569 // TRAIL binding // inferred from electronic annotation 210486_at AL136618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136618.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564N1623 (from clone DKFZp564N1623); complete cds. /FEA=mRNA /GEN=DKFZp564N1623 /PROD=hypothetical protein /DB_XREF=gi:12052761 /UG=Hs.262023 Homo sapiens mRNA; cDNA DKFZp564N1623 (from clone DKFZp564N1623); complete cds /FL=gb:AL136618.1 AL136618 ankyrin repeat and MYND domain containing 1 ANKMY1 51281 NM_001282771 /// NM_001282780 /// NM_001282781 /// NM_016552 /// NM_017844 /// XM_005247020 /// XM_006712567 /// XM_006712568 /// XM_006712569 /// XM_006712570 /// XM_006712571 /// XM_006712572 0046872 // metal ion binding // inferred from electronic annotation 210487_at M11722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M11722.1 /DEF=Human terminal transferase mRNA, complete cds. /FEA=mRNA /GEN=LA0024A /PROD=terminal transferase /DB_XREF=gi:339436 /UG=Hs.272537 deoxynucleotidyltransferase, terminal /FL=gb:M11722.1 gb:NM_004088.1 M11722 DNA nucleotidylexotransferase DNTT 1791 NM_001017520 /// NM_004088 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006304 // DNA modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0003912 // DNA nucleotidylexotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210491_at AF119888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119888.1 /DEF=Homo sapiens PRO2613 mRNA, complete cds. /FEA=mRNA /PROD=PRO2613 /DB_XREF=gi:7770212 /UG=Hs.283942 Homo sapiens PRO2613 mRNA, complete cds /FL=gb:AF119888.1 AF119888 210492_at BC001279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001279.1 /DEF=Homo sapiens, Similar to KIAA0626 gene product, clone MGC:5129, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0626 gene product /DB_XREF=gi:12654870 /UG=Hs.285318 Homo sapiens, Similar to KIAA0626 gene product, clone MGC:5129, mRNA, complete cds /FL=gb:BC001279.1 BC001279 uncharacterized LOC101928198 /// microfibrillar-associated protein 3-like LOC101928198 /// MFAP3L 9848 /// 101928198 NM_001009554 /// NM_021647 /// XM_005263366 /// XM_005263368 /// XM_005263369 /// XM_005263370 /// XM_005263371 /// XM_006714423 /// XM_006714424 /// XM_006714425 /// XM_006714426 /// XM_006714427 /// XM_006714428 /// XR_244749 /// XR_249692 /// XR_251689 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210493_s_at BC001279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001279.1 /DEF=Homo sapiens, Similar to KIAA0626 gene product, clone MGC:5129, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0626 gene product /DB_XREF=gi:12654870 /UG=Hs.285318 Homo sapiens, Similar to KIAA0626 gene product, clone MGC:5129, mRNA, complete cds /FL=gb:BC001279.1 BC001279 uncharacterized LOC101928198 /// microfibrillar-associated protein 3-like LOC101928198 /// MFAP3L 9848 /// 101928198 NM_001009554 /// NM_021647 /// XM_005263366 /// XM_005263368 /// XM_005263369 /// XM_005263370 /// XM_005263371 /// XM_006714423 /// XM_006714424 /// XM_006714425 /// XM_006714426 /// XM_006714427 /// XM_006714428 /// XR_244749 /// XR_249692 /// XR_251689 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210495_x_at AF130095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130095.1 /DEF=Homo sapiens clone FLC0562 PRO2841 mRNA, complete cds. /FEA=mRNA /PROD=PRO2841 /DB_XREF=gi:11493493 /UG=Hs.287820 fibronectin 1 /FL=gb:AF130095.1 AF130095 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 210496_at AF210651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF210651.1 /DEF=Homo sapiens NAG18 (NAG18) mRNA, complete cds. /FEA=mRNA /GEN=NAG18 /PROD=NAG18 /DB_XREF=gi:9802008 /UG=Hs.288736 NAG18 protein /FL=gb:AF210651.1 AF210651 NAG18 mRNA NAG18 57051 NM_020392 /// NR_002568 210497_x_at BC002818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002818.1 /DEF=Homo sapiens, Similar to synovial sarcoma, X breakpoint 2, clone MGC:3884, mRNA, complete cds. /FEA=mRNA /PROD=Similar to synovial sarcoma, X breakpoint 2 /DB_XREF=gi:12803942 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 /FL=gb:BC002818.1 BC002818 synovial sarcoma, X breakpoint 2 /// synovial sarcoma, X breakpoint 2B SSX2 /// SSX2B 6757 /// 727837 NM_001164417 /// NM_001278697 /// NM_001278701 /// NM_001278702 /// NM_003147 /// NM_175698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210498_at AF130062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130062.1 /DEF=Homo sapiens clone FLB7715 PRO2051 mRNA, complete cds. /FEA=mRNA /PROD=PRO2051 /DB_XREF=gi:11493430 /UG=Hs.302146 Homo sapiens clone FLB7715 PRO2051 mRNA, complete cds /FL=gb:AF130062.1 AF130062 clathrin, heavy chain (Hc) CLTC 1213 NM_001288653 /// NM_004859 /// XM_005257012 0001649 // osteoblast differentiation // inferred from direct assay /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032051 // clathrin light chain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210499_s_at AB041834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB041834.1 /DEF=Homo sapiens mRNA for PQBP-1bc, complete cds. /FEA=mRNA /PROD=PQBP-1bc /DB_XREF=gi:10801589 /UG=Hs.30570 polyglutamine binding protein 1 /FL=gb:AB041834.1 AB041834 polyglutamine binding protein 1 PQBP1 10084 NM_001032381 /// NM_001032382 /// NM_001032383 /// NM_001032384 /// NM_001032385 /// NM_001167989 /// NM_001167990 /// NM_001167992 /// NM_005710 /// NM_144494 /// NM_144495 /// XM_005272571 /// XM_005272572 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 210500_at BC001957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001957.1 /DEF=Homo sapiens, Similar to KIAA0144 gene product, clone MGC:761, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0144 gene product /DB_XREF=gi:12805006 /UG=Hs.306975 Homo sapiens, Similar to KIAA0144 gene product, clone MGC:761, mRNA, complete cds /FL=gb:BC001957.1 BC001957 210501_x_at AF119846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF119846.1 /DEF=Homo sapiens PRO1474 mRNA, complete cds. /FEA=mRNA /PROD=PRO1474 /DB_XREF=gi:7770128 /UG=Hs.324925 LATS (large tumor suppressor, Drosophila) homolog 1 /FL=gb:AF119846.1 AF119846 eukaryotic translation initiation factor 3, subunit K EIF3K 27335 NM_013234 /// XM_006723147 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation 210502_s_at AF042386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF042386.1 /DEF=Homo sapiens cyclophilin-33B (CYP-33) mRNA, complete cds. /FEA=mRNA /GEN=CYP-33 /PROD=cyclophilin-33B /DB_XREF=gi:2828150 /UG=Hs.33251 peptidylprolyl isomerase E (cyclophilin E) /FL=gb:AF042386.1 AF042386 peptidylprolyl isomerase E (cyclophilin E) PPIE 10450 NM_001195007 /// NM_006112 /// NM_203456 /// NM_203457 /// NR_036543 /// NR_036544 /// XM_006710288 /// XM_006710289 /// XM_006710290 /// XM_006710291 /// XM_006710292 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0000413 // protein peptidyl-prolyl isomerization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210503_at BC004479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004479.1 /DEF=Homo sapiens, melanoma antigen, family A, 11, clone MGC:10511, mRNA, complete cds. /FEA=mRNA /PROD=melanoma antigen, family A, 11 /DB_XREF=gi:13325333 /UG=Hs.37106 melanoma antigen, family A, 11 /FL=gb:BC004479.1 gb:NM_005366.1 BC004479 melanoma antigen family A, 11 MAGEA11 4110 NM_001011544 /// NM_005366 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210504_at U65404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U65404.1 /DEF=Human erythroid-specific transcription factor EKLF mRNA, complete cds. /FEA=mRNA /PROD=erythroid-specific transcription factor EKLF /DB_XREF=gi:1552995 /UG=Hs.37860 Kruppel-like factor 1 (erythroid) /FL=gb:NM_006563.1 gb:U65404.1 U65404 Kruppel-like factor 1 (erythroid) KLF1 10661 NM_006563 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048821 // erythrocyte development // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210505_at U07821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U07821.1 /DEF=Human alcohol dehydrogenase (ADH7) mRNA, complete cds. /FEA=mRNA /GEN=ADH7 /PROD=alcohol dehydrogenase /DB_XREF=gi:499097 /UG=Hs.389 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide /FL=gb:NM_000673.2 gb:U07821.1 gb:L33179.1 gb:U09623.1 U07821 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ADH7 131 NM_000673 /// NM_001166504 0001523 // retinoid metabolic process // inferred from direct assay /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0009617 // response to bacterium // inferred from direct assay /// 0010430 // fatty acid omega-oxidation // inferred from direct assay /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 1900116 // extracellular negative regulation of signal transduction // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004022 // alcohol dehydrogenase (NAD) activity // traceable author statement /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0004031 // aldehyde oxidase activity // inferred from direct assay /// 0004745 // retinol dehydrogenase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019841 // retinol binding // inferred from direct assay /// 0035276 // ethanol binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // inferred from direct assay 210506_at U11282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U11282.1 /DEF=Human alpha(1,3)fucosyltransferase mRNA, complete cds. /FEA=mRNA /PROD=alpha(1,3)fucosyltransferase /DB_XREF=gi:520524 /UG=Hs.457 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) /FL=gb:NM_004479.1 gb:U08112.1 gb:U11282.1 U11282 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) FUT7 2529 NM_004479 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0002522 // leukocyte migration involved in immune response // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 210507_s_at BC004134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004134.1 /DEF=Homo sapiens, Similar to advillin, clone MGC:1461, mRNA, complete cds. /FEA=mRNA /PROD=Similar to advillin /DB_XREF=gi:13278707 /UG=Hs.47344 advillin /FL=gb:BC004134.1 gb:BC004197.1 BC004134 advillin AVIL 10677 NM_006576 /// XM_006719198 0006950 // response to stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 210508_s_at D82346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D82346.1 /DEF=Homo sapiens mRNA for HNSPC, complete cds. /FEA=mRNA /PROD=HNSPC /DB_XREF=gi:1841341 /UG=Hs.4975 potassium voltage-gated channel, KQT-like subfamily, member 2 /FL=gb:BC000699.1 gb:D82346.1 D82346 potassium voltage-gated channel, KQT-like subfamily, member 2 KCNQ2 3785 NM_004518 /// NM_172106 /// NM_172107 /// NM_172108 /// NM_172109 /// XM_006723787 /// XM_006723788 /// XM_006723789 /// XM_006723790 /// XM_006723791 /// XM_006723792 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction 210510_s_at AF145712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF145712.1 /DEF=Homo sapiens soluble neuropilin-1 mRNA, complete cds. /FEA=mRNA /PROD=soluble neuropilin-1 /DB_XREF=gi:7271464 /UG=Hs.69285 neuropilin 1 /FL=gb:AF145712.1 AF145712 neuropilin 1 NRP1 8829 NM_001024628 /// NM_001024629 /// NM_001244972 /// NM_001244973 /// NM_003873 /// NR_045259 /// XM_006717521 /// XM_006717522 /// XM_006717523 /// XM_006717524 /// XM_006717525 /// XM_006717526 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021636 // trigeminal nerve morphogenesis // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from mutant phenotype /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048841 // regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0060301 // positive regulation of cytokine activity // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from sequence or structural similarity /// 0060627 // regulation of vesicle-mediated transport // traceable author statement /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0060978 // angiogenesis involved in coronary vascular morphogenesis // inferred from sequence or structural similarity /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // non-traceable author statement /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0097102 // endothelial tip cell fate specification // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1901166 // neural crest cell migration involved in autonomic nervous system development // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902946 // protein localization to early endosome // inferred from sequence or structural similarity /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005883 // neurofilament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // traceable author statement /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0015026 // coreceptor activity // traceable author statement /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210511_s_at M13436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13436.1 /DEF=Human ovarian beta-A inhibin mRNA, complete cds. /FEA=mRNA /GEN=INHBA /DB_XREF=gi:186414 /UG=Hs.727 inhibin, beta A (activin A, activin AB alpha polypeptide) /FL=gb:M13436.1 M13436 inhibin, beta A INHBA 3624 NM_002192 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from genetic interaction /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from genetic interaction /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from genetic interaction /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // traceable author statement /// 0030218 // erythrocyte differentiation // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0035987 // endodermal cell differentiation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // traceable author statement /// 0042476 // odontogenesis // inferred from genetic interaction /// 0042493 // response to drug // inferred from direct assay /// 0042541 // hemoglobin biosynthetic process // inferred from direct assay /// 0042701 // progesterone secretion // inferred from genetic interaction /// 0045077 // negative regulation of interferon-gamma biosynthetic process // traceable author statement /// 0045578 // negative regulation of B cell differentiation // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045650 // negative regulation of macrophage differentiation // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046880 // regulation of follicle-stimulating hormone secretion // inferred from genetic interaction /// 0046881 // positive regulation of follicle-stimulating hormone secretion // traceable author statement /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0051799 // negative regulation of hair follicle development // inferred from direct assay /// 0060021 // palate development // inferred from genetic interaction /// 0060279 // positive regulation of ovulation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0043509 // activin A complex // inferred from direct assay /// 0043512 // inhibin A complex // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070699 // type II activin receptor binding // inferred from physical interaction 210512_s_at AF022375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022375.1 /DEF=Homo sapiens vascular endothelial growth factor mRNA, complete cds. /FEA=mRNA /PROD=vascular endothelial growth factor /DB_XREF=gi:3719220 /UG=Hs.73793 vascular endothelial growth factor /FL=gb:M32977.1 gb:AF022375.1 gb:NM_003376.1 gb:AB021221.1 gb:AF091352.1 AF022375 vascular endothelial growth factor A VEGFA 7422 NM_001025366 /// NM_001025367 /// NM_001025368 /// NM_001025369 /// NM_001025370 /// NM_001033756 /// NM_001171622 /// NM_001171623 /// NM_001171624 /// NM_001171625 /// NM_001171626 /// NM_001171627 /// NM_001171628 /// NM_001171629 /// NM_001171630 /// NM_001204384 /// NM_001204385 /// NM_001287044 /// NM_003376 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0002575 // basophil chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // traceable author statement /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003169 // coronary vein morphogenesis // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009409 // response to cold // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030225 // macrophage differentiation // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0031077 // post-embryonic camera-type eye development // inferred from sequence or structural similarity /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032793 // positive regulation of CREB transcription factor activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035148 // tube formation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036303 // lymph vessel morphogenesis // inferred from sequence or structural similarity /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0040007 // growth // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060319 // primitive erythrocyte differentiation // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060948 // cardiac vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090037 // positive regulation of protein kinase C signaling // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901492 // positive regulation of lymphangiogenesis // inferred from electronic annotation /// 1901727 // positive regulation of histone deacetylase activity // inferred from direct assay /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay /// 1902966 // positive regulation of protein localization to early endosome // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0001968 // fibronectin binding // inferred from direct assay /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005172 // vascular endothelial growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0038191 // neuropilin binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred by curator 210513_s_at AF091352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF091352.1 /DEF=Homo sapiens vascular permeability factor 148 mRNA, complete cds. /FEA=mRNA /PROD=vascular permeability factor 148 /DB_XREF=gi:5901560 /UG=Hs.73793 vascular endothelial growth factor /FL=gb:M32977.1 gb:AF022375.1 gb:NM_003376.1 gb:AB021221.1 gb:AF091352.1 AF091352 vascular endothelial growth factor A VEGFA 7422 NM_001025366 /// NM_001025367 /// NM_001025368 /// NM_001025369 /// NM_001025370 /// NM_001033756 /// NM_001171622 /// NM_001171623 /// NM_001171624 /// NM_001171625 /// NM_001171626 /// NM_001171627 /// NM_001171628 /// NM_001171629 /// NM_001171630 /// NM_001204384 /// NM_001204385 /// NM_001287044 /// NM_003376 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0002575 // basophil chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // traceable author statement /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003169 // coronary vein morphogenesis // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009409 // response to cold // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030225 // macrophage differentiation // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0031077 // post-embryonic camera-type eye development // inferred from sequence or structural similarity /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032793 // positive regulation of CREB transcription factor activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035148 // tube formation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036303 // lymph vessel morphogenesis // inferred from sequence or structural similarity /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0040007 // growth // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060319 // primitive erythrocyte differentiation // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060948 // cardiac vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090037 // positive regulation of protein kinase C signaling // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901492 // positive regulation of lymphangiogenesis // inferred from electronic annotation /// 1901727 // positive regulation of histone deacetylase activity // inferred from direct assay /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay /// 1902966 // positive regulation of protein localization to early endosome // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0001968 // fibronectin binding // inferred from direct assay /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005172 // vascular endothelial growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0038191 // neuropilin binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred by curator 210514_x_at AF226990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF226990.2 /DEF=Homo sapiens MHC class I antigen (HLA-G) mRNA, HLA-G1 allele, complete cds. /FEA=mRNA /GEN=HLA-G /PROD=MHC class I antigen /DB_XREF=gi:7245285 /UG=Hs.73885 HLA-G histocompatibility antigen, class I, G /FL=gb:M90683.1 gb:M32800.1 gb:NM_002127.1 gb:AF226990.2 AF226990 major histocompatibility complex, class I, G HLA-G 3135 NM_002127 /// XM_006715080 /// XM_006725041 /// XM_006725700 /// XM_006725909 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001199 // negative regulation of dendritic cell differentiation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042803 // protein homodimerization activity // non-traceable author statement 210515_at M57732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M57732.1 /DEF=Human hepatic nuclear factor 1 (TCF1) mRNA, complete cds, clones HCL10, HCL12, HCL17, and HCL20. /FEA=mRNA /GEN=TCF1 /PROD=hepatic nuclear factor 1 /DB_XREF=gi:184264 /UG=Hs.73888 transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor /FL=gb:M57732.1 gb:NM_000545.1 M57732 HNF1 homeobox A HNF1A 6927 NM_000545 /// XM_005253931 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from mutant phenotype /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0035565 // regulation of pronephros size // inferred from mutant phenotype /// 0035623 // renal glucose absorption // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046323 // glucose import // inferred from mutant phenotype /// 0046883 // regulation of hormone secretion // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from genetic interaction /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from physical interaction 210516_at AF214738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF214738.1 /DEF=Homo sapiens C9orf10b mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=C9orf10b /DB_XREF=gi:8118022 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214738.1 AF214738 family with sequence similarity 120A FAM120A 23196 NM_001286722 /// NM_001286723 /// NM_001286724 /// NM_014612 /// XM_005251842 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210517_s_at AB003476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB003476.1 /DEF=Homo sapiens mRNA for gravin, complete cds. /FEA=mRNA /PROD=gravin /DB_XREF=gi:2081606 /UG=Hs.788 A kinase (PRKA) anchor protein (gravin) 12 /FL=gb:AB003476.1 AB003476 A kinase (PRKA) anchor protein 12 AKAP12 9590 NM_005100 /// NM_144497 /// XM_005267233 /// XM_005267234 /// XM_005267235 0006605 // protein targeting // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0010739 // positive regulation of protein kinase A signaling // inferred from mutant phenotype /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from physical interaction /// 0051018 // protein kinase A binding // inferred from electronic annotation 210518_at AB035305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035305.1 /DEF=Homo sapiens CDH8 mRNA for cadherin-8, complete cds. /FEA=mRNA /GEN=CDH8 /PROD=cadherin-8 /DB_XREF=gi:6483314 /UG=Hs.79133 cadherin 8, type 2 /FL=gb:NM_001796.1 gb:L34060.1 gb:AB035305.1 AB035305 cadherin 8, type 2 CDH8 1006 NM_001796 /// XM_005255759 /// XM_005255760 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043083 // synaptic cleft // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210519_s_at BC000906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000906.1 /DEF=Homo sapiens, clone MGC:5333, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5333) /DB_XREF=gi:12654176 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:BC000906.1 BC000906 NAD(P)H dehydrogenase, quinone 1 NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 /// NM_001286137 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210520_at AB017551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB017551.1 /DEF=Homo sapiens mRNA for 16G2, complete cds. /FEA=mRNA /GEN=16G2 /PROD=16G2 /DB_XREF=gi:4996125 /UG=Hs.81073 fetuin B /FL=gb:AB017551.1 gb:NM_014375.1 AB017551 210521_s_at AB017551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017551.1 /DEF=Homo sapiens mRNA for 16G2, complete cds. /FEA=mRNA /GEN=16G2 /PROD=16G2 /DB_XREF=gi:4996125 /UG=Hs.81073 fetuin B /FL=gb:AB017551.1 gb:NM_014375.1 AB017551 fetuin B FETUB 26998 NM_014375 /// XM_005247350 /// XM_005247351 0007338 // single fertilization // inferred from sequence or structural similarity /// 0007339 // binding of sperm to zona pellucida // inferred from sequence or structural similarity /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from sequence or structural similarity /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210523_at D89675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89675.1 /DEF=Homo sapiens mRNA for bone morphogenetic protein type IB receptor, complete cds. /FEA=mRNA /PROD=bone morphogenetic protein type IB receptor /DB_XREF=gi:2055308 /UG=Hs.87223 bone morphogenetic protein receptor, type IB /FL=gb:D89675.1 gb:U89326.1 gb:NM_001203.1 D89675 bone morphogenetic protein receptor, type IB BMPR1B 658 NM_001203 /// NM_001256792 /// NM_001256793 /// NM_001256794 /// XM_006714292 0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // non-traceable author statement /// 0001550 // ovarian cumulus expansion // inferred from sequence or structural similarity /// 0001654 // eye development // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // non-traceable author statement /// 0030509 // BMP signaling pathway // traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0042698 // ovulation cycle // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210524_x_at AF078844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078844.1 /DEF=Homo sapiens hqp0376 protein mRNA, complete cds. /FEA=mRNA /PROD=hqp0376 protein /DB_XREF=gi:6683748 /UG=Hs.8765 RNA helicase-related protein /FL=gb:AF078844.1 AF078844 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 210525_x_at BC001787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001787.1 /DEF=Homo sapiens, clone MGC:2492, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2492) /DB_XREF=gi:12804712 /UG=Hs.87819 Homo sapiens, clone MGC:2492, mRNA, complete cds /FL=gb:BC001787.1 BC001787 EF-hand calcium binding domain 11 EFCAB11 90141 NM_001284266 /// NM_001284267 /// NM_001284268 /// NM_001284269 /// NM_145231 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210527_x_at L11645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11645.1 /DEF=Homo sapiens alpha-tubulin mRNA, complete cds. /FEA=mRNA /PROD=alpha-tubulin /DB_XREF=gi:306450 /UG=Hs.98102 tubulin, alpha 2 /FL=gb:L11645.1 L11645 tubulin, alpha 3c /// tubulin, alpha 3d TUBA3C /// TUBA3D 7278 /// 113457 NM_006001 /// NM_079836 /// NM_080386 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 210528_at AF010447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010447.1 /DEF=Homo sapiens MHC class I related protein 1 isoform C (MR1C) mRNA, complete cds. /FEA=mRNA /GEN=MR1C /PROD=MHC class I related protein 1 isoform C /DB_XREF=gi:4102223 /UG=Hs.101840 major histocompatibility complex, class I-like sequence /FL=gb:AF010447.1 AF010447 major histocompatibility complex, class I-related MR1 3140 NM_001194999 /// NM_001195000 /// NM_001195035 /// NM_001531 /// XM_005245115 /// XM_006711286 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032620 // interleukin-17 production // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0032393 // MHC class I receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 210529_s_at BC000609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000609.1 /DEF=Homo sapiens, KIAA0738 gene product, clone MGC:1890, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0738 gene product /DB_XREF=gi:12653652 /UG=Hs.107479 KIAA0738 gene product /FL=gb:BC000609.1 BC000609 family with sequence similarity 115, member A /// protein FAM115A-like FAM115A /// LOC100294033 9747 /// 100294033 NM_001206938 /// NM_001206941 /// NM_014719 /// XM_003120061 /// XM_005250074 /// XM_005250075 /// XM_005250076 /// XM_005250077 /// XM_006716190 /// XM_006716191 /// XM_006716192 /// XM_006716193 210530_s_at M21985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21985.1 /DEF=Human steroid receptor TR2 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:338485 /UG=Hs.108301 nuclear receptor subfamily 2, group C, member 1 /FL=gb:M21985.1 M21985 nuclear receptor subfamily 2, group C, member 1 NR2C1 7181 NM_001032287 /// NM_001127362 /// NM_003297 /// XM_005269133 /// XM_006719584 /// XM_006719585 /// XM_006719586 /// XR_245956 /// XR_429114 /// XR_429115 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210531_at M21985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21985.1 /DEF=Human steroid receptor TR2 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:338485 /UG=Hs.108301 nuclear receptor subfamily 2, group C, member 1 /FL=gb:M21985.1 M21985 nuclear receptor subfamily 2, group C, member 1 NR2C1 7181 NM_001032287 /// NM_001127362 /// NM_003297 /// XM_005269133 /// XM_006719584 /// XM_006719585 /// XM_006719586 /// XR_245956 /// XR_429114 /// XR_429115 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210532_s_at AF116639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116639.1 /DEF=Homo sapiens PRO1574 mRNA, complete cds. /FEA=mRNA /PROD=PRO1574 /DB_XREF=gi:7959779 /UG=Hs.109052 chromosome 14 open reading frame 2 /FL=gb:AF116639.1 AF116639 chromosome 14 open reading frame 2 C14orf2 9556 NM_001127393 /// NM_004894 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 210533_at AF104243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF104243.1 /DEF=Homo sapiens meiosis-specific MutS homolog (MSH4) mRNA, complete cds. /FEA=mRNA /GEN=MSH4 /PROD=meiosis-specific MutS homolog /DB_XREF=gi:4336727 /UG=Hs.115246 mutS (E. coli) homolog 4 /FL=gb:U89293.1 gb:AF104243.1 gb:NM_002440.1 AF104243 mutS homolog 4 MSH4 4438 NM_002440 0000710 // meiotic mismatch repair // not recorded /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006200 // ATP catabolic process // not recorded /// 0006298 // mismatch repair // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007292 // female gamete generation // inferred from electronic annotation /// 0045143 // homologous chromosome segregation // not recorded /// 0051026 // chiasma assembly // not recorded 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0005634 // nucleus // traceable author statement /// 0032300 // mismatch repair complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0030983 // mismatched DNA binding // not recorded 210534_s_at BC002944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002944.1 /DEF=Homo sapiens, Similar to B9 protein, clone MGC:11339, mRNA, complete cds. /FEA=mRNA /PROD=Similar to B9 protein /DB_XREF=gi:12804172 /UG=Hs.11955 B9 protein /FL=gb:BC002944.1 BC002944 B9 protein domain 1 B9D1 27077 NM_001243473 /// NM_001243475 /// NM_015681 /// XM_005256605 /// XM_005256607 /// XM_005256608 /// XM_005256609 /// XM_005256610 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008158 // hedgehog receptor activity // inferred from sequence or structural similarity 210535_at BC002944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002944.1 /DEF=Homo sapiens, Similar to B9 protein, clone MGC:11339, mRNA, complete cds. /FEA=mRNA /PROD=Similar to B9 protein /DB_XREF=gi:12804172 /UG=Hs.11955 B9 protein /FL=gb:BC002944.1 BC002944 B9 protein domain 1 B9D1 27077 NM_001243473 /// NM_001243475 /// NM_015681 /// XM_005256605 /// XM_005256607 /// XM_005256608 /// XM_005256609 /// XM_005256610 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0008158 // hedgehog receptor activity // inferred from sequence or structural similarity 210536_s_at S67798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S67798.1 /DEF=Homo sapiens PH-20 (SPAM1) mRNA, complete cds. /FEA=mRNA /GEN=SPAM1 /PROD=PH-20 /DB_XREF=gi:459386 /UG=Hs.121494 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) /FL=gb:NM_003117.1 gb:S67798.1 S67798 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) SPAM1 6677 NM_001174044 /// NM_001174045 /// NM_001174046 /// NM_003117 /// NM_153189 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0035036 // sperm-egg recognition // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 210537_s_at BC001172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001172.1 /DEF=Homo sapiens, Similar to transcriptional adaptor 2 (ADA2, yeast, homolog)-like, clone MGC:1984, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transcriptional adaptor 2 (ADA2,yeast, homolog)-like /DB_XREF=gi:12654666 /UG=Hs.125156 transcriptional adaptor 2 (ADA2, yeast, homolog)-like /FL=gb:BC001172.1 BC001172 transcriptional adaptor 2A TADA2A 6871 NM_001166105 /// NM_001291918 /// NM_001488 /// NM_133439 /// XM_005257628 /// XM_006722043 /// XM_006722044 /// XM_006722045 /// XM_006722046 /// XM_006722047 /// XM_006725335 /// XM_006725336 /// XM_006725337 /// XM_006725338 /// XM_006725339 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0090043 // regulation of tubulin deacetylation // inferred from electronic annotation 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation 210538_s_at U37546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U37546.1 /DEF=Human IAP homolog C (MIHC) mRNA, complete cds. /FEA=mRNA /GEN=MIHC /PROD=MIHC /DB_XREF=gi:1145290 /UG=Hs.127799 baculoviral IAP repeat-containing 3 /FL=gb:U37546.1 U37546 baculoviral IAP repeat containing 3 BIRC3 330 NM_001165 /// NM_182962 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0034121 // regulation of toll-like receptor signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0039535 // regulation of RIG-I signaling pathway // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045088 // regulation of innate immune response // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0060544 // regulation of necroptotic process // inferred from mutant phenotype /// 0060546 // negative regulation of necroptotic process // inferred from electronic annotation /// 0070266 // necroptotic process // inferred from electronic annotation /// 0070424 // regulation of nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 2000116 // regulation of cysteine-type endopeptidase activity // traceable author statement /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210539_at AK024259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024259.1 /DEF=Homo sapiens cDNA FLJ14197 fis, clone NT2RP3002484, highly similar to Homo sapiens mRNA for KIAA0998 protein. /FEA=mRNA /DB_XREF=gi:10436591 /UG=Hs.131525 KIAA0998 protein /FL=gb:BC002766.1 AK024259 tubulin tyrosine ligase-like family, member 5 TTLL5 23093 NM_015072 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 210540_s_at BC004523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004523.1 /DEF=Homo sapiens, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4, clone MGC:3811, mRNA, complete cds. /FEA=mRNA /PROD=UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4 /DB_XREF=gi:13325453 /UG=Hs.13225 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 /FL=gb:AF020920.1 gb:BC004523.1 gb:AF038662.1 gb:NM_003778.1 BC004523 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 B4GALT4 8702 NM_003778 /// NM_212543 /// XM_005247855 /// XM_005247857 /// XM_006713798 /// XM_006713799 /// XM_006713800 /// XM_006713801 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006643 // membrane lipid metabolic process // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003945 // N-acetyllactosamine synthase activity // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210541_s_at AF230394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230394.1 /DEF=Homo sapiens tripartite motif protein TRIM27 beta mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM27 beta /DB_XREF=gi:12275875 /UG=Hs.142653 ret finger protein /FL=gb:AF230394.1 AF230394 tripartite motif containing 27 TRIM27 5987 NM_006510 /// NM_030950 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002820 // negative regulation of adaptive immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype /// 0090281 // negative regulation of calcium ion import // inferred from mutant phenotype /// 1900041 // negative regulation of interleukin-2 secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016605 // PML body // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // traceable author statement 210542_s_at BC000585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000585.1 /DEF=Homo sapiens, Similar to solute carrier family 21 (organic anion transporter), member 11, clone MGC:659, mRNA, complete cds. /FEA=mRNA /PROD=Similar to solute carrier family 21 (organicanion transporter), member 11 /DB_XREF=gi:12653614 /UG=Hs.14805 solute carrier family 21 (organic anion transporter), member 11 /FL=gb:BC000585.1 BC000585 solute carrier organic anion transporter family, member 3A1 SLCO3A1 28232 NM_001145044 /// NM_013272 /// XM_005254889 /// XM_005254891 /// XM_006720472 /// XR_429450 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210543_s_at U34994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34994.3 /DEF=Homo sapiens DNA dependent protein kinase catalytic subunit (PRKDC) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=PRKDC /PROD=DNA dependent protein kinase catalytic subunit /DB_XREF=gi:13606055 /UG=Hs.155637 protein kinase, DNA-activated, catalytic polypeptide /FL=gb:U34994.3 U34994 protein kinase, DNA-activated, catalytic polypeptide PRKDC 5591 NM_001081640 /// NM_006904 0000723 // telomere maintenance // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0072431 // signal transduction involved in mitotic G1 DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210544_s_at BC002430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002430.1 /DEF=Homo sapiens, aldehyde dehydrogenase 10 (fatty aldehyde dehydrogenase), clone MGC:2136, mRNA, complete cds. /FEA=mRNA /PROD=aldehyde dehydrogenase 10 (fatty aldehydedehydrogenase) /DB_XREF=gi:12803234 /UG=Hs.159608 aldehyde dehydrogenase 3 family, member A2 /FL=gb:BC002430.1 BC002430 aldehyde dehydrogenase 3 family, member A2 ALDH3A2 224 NM_000382 /// NM_001031806 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0006081 // cellular aldehyde metabolic process // non-traceable author statement /// 0006714 // sesquiterpenoid metabolic process // inferred from direct assay /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007422 // peripheral nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0033306 // phytol metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from mutant phenotype /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046577 // long-chain-alcohol oxidase activity // inferred from direct assay /// 0050061 // long-chain-aldehyde dehydrogenase activity // inferred from direct assay /// 0052814 // medium-chain-aldehyde dehydrogenase activity // inferred from direct assay 210545_at AF182199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182199.1 /DEF=Homo sapiens intersectin 2 short isoform (ITSN2) mRNA, complete cds. /FEA=mRNA /GEN=ITSN2 /PROD=intersectin 2 short isoform /DB_XREF=gi:7329077 /UG=Hs.166184 intersectin 2 /FL=gb:AF182199.1 AF182199 intersectin 2 ITSN2 50618 NM_006277 /// NM_019595 /// NM_147152 0006897 // endocytosis // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210546_x_at U87459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87459.1 /DEF=Human autoimmunogenic cancertestis antigen NY-ESO-1 mRNA, complete cds. /FEA=mRNA /PROD=autoimmunogenic cancertestis antigen NY-ESO-1 /DB_XREF=gi:1890098 /UG=Hs.167379 cancertestis antigen /FL=gb:U87459.1 gb:NM_001327.1 U87459 cancer/testis antigen 1A /// cancer/testis antigen 1B CTAG1A /// CTAG1B 1485 /// 246100 NM_001327 /// NM_139250 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210547_x_at L21181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L21181.1 /DEF=Human autoantigen p69 mRNA, complete cds. /FEA=mRNA /PROD=autoantigen p69 /DB_XREF=gi:437366 /UG=Hs.167927 islet cell autoantigen 1 (69kD) /FL=gb:L21181.1 L21181 islet cell autoantigen 1, 69kDa ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 210548_at U58913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58913.1 /DEF=Human chemokine (hmrp-2a) mRNA, complete cds. /FEA=mRNA /GEN=hmrp-2a /PROD=chemokine /DB_XREF=gi:4204907 /UG=Hs.169191 small inducible cytokine subfamily A (Cys-Cys), member 23 /FL=gb:U58913.1 U58913 chemokine (C-C motif) ligand 23 CCL23 6368 NM_005064 /// NM_145898 /// XR_429910 /// XR_430786 0002548 // monocyte chemotaxis // inferred by curator /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 2001264 // negative regulation of C-C chemokine binding // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction 210549_s_at U58913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58913.1 /DEF=Human chemokine (hmrp-2a) mRNA, complete cds. /FEA=mRNA /GEN=hmrp-2a /PROD=chemokine /DB_XREF=gi:4204907 /UG=Hs.169191 small inducible cytokine subfamily A (Cys-Cys), member 23 /FL=gb:U58913.1 U58913 chemokine (C-C motif) ligand 23 CCL23 6368 NM_005064 /// NM_145898 /// XR_429910 /// XR_430786 0002548 // monocyte chemotaxis // inferred by curator /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 2001264 // negative regulation of C-C chemokine binding // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction 210550_s_at L26584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L26584.1 /DEF=Human (CDC25) mRNA, complete cds. /FEA=mRNA /GEN=CDC25 /DB_XREF=gi:433719 /UG=Hs.169350 Ras protein-specific guanine nucleotide-releasing factor 1 /FL=gb:L26584.1 L26584 Ras protein-specific guanine nucleotide-releasing factor 1 RASGRF1 5923 NM_001145648 /// NM_002891 /// NM_153815 /// XM_005254578 /// XM_006720627 /// XM_006720628 /// XM_006720629 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007616 // long-term memory // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0043005 // neuron projection // non-traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation 210551_s_at BC001620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001620.1 /DEF=Homo sapiens, acetylserotonin O-methyltransferase, clone MGC:2145, mRNA, complete cds. /FEA=mRNA /PROD=acetylserotonin O-methyltransferase /DB_XREF=gi:12804428 /UG=Hs.169609 acetylserotonin O-methyltransferase /FL=gb:BC001620.1 BC001620 acetylserotonin O-methyltransferase ASMT 438 NM_001171038 /// NM_001171039 /// NM_004043 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042113 // B cell activation // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 2000019 // negative regulation of male gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 210552_s_at AF221098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF221098.1 /DEF=Homo sapiens Ral guanine nucleotide exchange factor RalGPS1A mRNA, complete cds. /FEA=mRNA /PROD=Ral guanine nucleotide exchange factor RalGPS1A /DB_XREF=gi:7637905 /UG=Hs.170307 Ral guanine nucleotide exchange factor RalGPS1A /FL=gb:AF221098.1 AF221098 Ral GEF with PH domain and SH3 binding motif 1 RALGPS1 9649 NM_001190728 /// NM_001190729 /// NM_001190730 /// NM_014636 /// XM_005252318 /// XM_006717327 /// XM_006717328 /// XM_006717329 /// XM_006717330 /// XM_006717331 /// XM_006717332 /// XM_006717333 /// XM_006717334 /// XM_006717335 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032315 // regulation of Ral GTPase activity // inferred from direct assay /// 0032485 // regulation of Ral protein signal transduction // inferred from direct assay /// 0032852 // positive regulation of Ral GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0008321 // Ral guanyl-nucleotide exchange factor activity // inferred from direct assay 210553_x_at D28514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28514.1 /DEF=Human mRNA for PACE4D, complete cds. /FEA=mRNA /PROD=PACE4D /DB_XREF=gi:666012 /UG=Hs.170414 paired basic amino acid cleaving system 4 /FL=gb:D28514.1 D28514 uncharacterized LOC100507472 /// proprotein convertase subtilisin/kexin type 6 LOC100507472 /// PCSK6 5046 /// 100507472 NM_001291309 /// NM_002570 /// NM_138319 /// NM_138320 /// NM_138321 /// NM_138322 /// NM_138323 /// NM_138324 /// NM_138325 /// NR_045387 0006508 // proteolysis // inferred from electronic annotation /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032940 // secretion by cell // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 210554_s_at BC002486 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002486.1 /DEF=Homo sapiens, C-terminal binding protein 2, clone MGC:1563, mRNA, complete cds. /FEA=mRNA /PROD=C-terminal binding protein 2 /DB_XREF=gi:12803334 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:BC002486.1 BC002486 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210555_s_at U85430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85430.1 /DEF=Human transcription factor NFATx4 mRNA, complete cds. /FEA=mRNA /PROD=transcription factor NFATx4 /DB_XREF=gi:1835590 /UG=Hs.172674 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 /FL=gb:U85430.1 U85430 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFATC3 4775 NM_004555 /// NM_173163 /// NM_173164 /// NM_173165 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045333 // cellular respiration // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210556_at U85430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85430.1 /DEF=Human transcription factor NFATx4 mRNA, complete cds. /FEA=mRNA /PROD=transcription factor NFATx4 /DB_XREF=gi:1835590 /UG=Hs.172674 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 /FL=gb:U85430.1 U85430 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFATC3 4775 NM_004555 /// NM_173163 /// NM_173164 /// NM_173165 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045333 // cellular respiration // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210557_x_at M76453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76453.1 /DEF=Human colony stimulating factor 1 (CSF1) gene, complete cds. /FEA=mRNA /GEN=CSF1 /PROD=colony stimulating factor 1 /DB_XREF=gi:393119 /UG=Hs.173894 colony stimulating factor 1 (macrophage) /FL=gb:M76453.1 M76453 colony stimulating factor 1 (macrophage) CSF1 1435 NM_000757 /// NM_172210 /// NM_172211 /// NM_172212 0001503 // ossification // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0003006 // developmental process involved in reproduction // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010743 // regulation of macrophage derived foam cell differentiation // non-traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0030097 // hemopoiesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042117 // monocyte activation // non-traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042488 // positive regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060611 // mammary gland fat development // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay /// 0005157 // macrophage colony-stimulating factor receptor binding // inferred from sequence or structural similarity /// 0005157 // macrophage colony-stimulating factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 210558_at AB045829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB045829.1 /DEF=Homo sapiens mRNA for 3alpha-hydroxysteroid dehydrogenase variant, complete cds. /FEA=mRNA /PROD=3alpha-hydroxysteroid dehydrogenase variant /DB_XREF=gi:9186907 /UG=Hs.177687 aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) /FL=gb:NM_001818.1 gb:M33375.1 gb:AB031085.1 gb:AB045829.1 AB045829 aldo-keto reductase family 1, member C4 AKR1C4 1109 NM_001818 0001523 // retinoid metabolic process // traceable author statement /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008206 // bile acid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0001758 // retinal dehydrogenase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0015125 // bile acid transmembrane transporter activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0047023 // androsterone dehydrogenase activity // inferred from direct assay /// 0047743 // chlordecone reductase activity // inferred from electronic annotation 210559_s_at D88357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D88357.1 /DEF=Homo sapiens mRNA for CDC2 delta T, complete cds. /FEA=mRNA /PROD=CDC2 delta T /DB_XREF=gi:3126638 /UG=Hs.184572 cell division cycle 2, G1 to S and G2 to M /FL=gb:D88357.1 D88357 cyclin-dependent kinase 1 CDK1 983 NM_001130829 /// NM_001170406 /// NM_001170407 /// NM_001786 /// NM_033379 /// XM_005270303 /// XM_006718082 /// XM_006718083 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007344 // pronuclear fusion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014038 // regulation of Schwann cell differentiation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045995 // regulation of embryonic development // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from electronic annotation 210560_at AF118452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118452.1 /DEF=Homo sapiens homeobox protein GBX2 mRNA, complete cds. /FEA=mRNA /PROD=homeobox protein GBX2 /DB_XREF=gi:5106977 /UG=Hs.184945 gastrulation brain homeo box 2 /FL=gb:NM_001485.1 gb:AF118452.1 AF118452 gastrulation brain homeobox 2 GBX2 2637 NM_001485 /// XM_005246071 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021568 // rhombomere 2 development // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0021930 // cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0030917 // midbrain-hindbrain boundary development // inferred from electronic annotation /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048483 // autonomic nervous system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210561_s_at AL110243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL110243.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B0482 (from clone DKFZp564B0482); complete cds. /FEA=mRNA /GEN=DKFZp564B0482 /PROD=hypothetical protein /DB_XREF=gi:5817189 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF072880.1 gb:AF106683.1 gb:AL110243.1 gb:AF112205.1 gb:AF069313.2 AL110243 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 210562_at AF245389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF245389.1 /DEF=Homo sapiens GREB1b (GREB1) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=GREB1 /PROD=GREB1b /DB_XREF=gi:11611735 /UG=Hs.190846 Homo sapiens GREB1b (GREB1) mRNA, complete cds, alternatively spliced /FL=gb:AF245389.1 AF245389 growth regulation by estrogen in breast cancer 1 GREB1 9687 NM_014668 /// NM_033090 /// NM_148903 /// XM_005246192 /// XM_005246195 /// XM_005246196 /// XM_005246197 /// XM_006711904 /// XM_006711905 /// XM_006711906 /// XM_006711907 /// XM_006711908 /// XR_426961 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210563_x_at U97075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U97075.1 /DEF=Homo sapiens FLICE-like inhibitory protein short form mRNA, complete cds. /FEA=mRNA /PROD=FLICE-like inhibitory protein short form /DB_XREF=gi:2253680 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:U97075.1 U97075 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 210564_x_at AF009619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009619.1 /DEF=Homo sapiens FLAME-1-delta mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=FLAME-1-delta /DB_XREF=gi:2429159 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF009619.1 AF009619 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 210565_at U03469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03469.1 /DEF=Human glucagon receptor mRNA, complete cds. /FEA=mRNA /PROD=glucagon receptor /DB_XREF=gi:439689 /UG=Hs.208 glucagon receptor /FL=gb:L20316.1 gb:U03469.1 gb:NM_000160.1 U03469 glucagon receptor GCGR 2642 NM_000160 /// XM_006722276 /// XM_006722277 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070873 // regulation of glycogen metabolic process // inferred from sequence or structural similarity /// 0071377 // cellular response to glucagon stimulus // inferred from direct assay /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0017046 // peptide hormone binding // inferred from electronic annotation 210567_s_at BC001441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001441.1 /DEF=Homo sapiens, Similar to S-phase kinase-associated protein 2 (p45), clone MGC:1366, mRNA, complete cds. /FEA=mRNA /PROD=Similar to S-phase kinase-associated protein 2(p45) /DB_XREF=gi:12655170 /UG=Hs.23348 S-phase kinase-associated protein 2 (p45) /FL=gb:BC001441.1 BC001441 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase SKP2 6502 NM_001243120 /// NM_005983 /// NM_032637 /// XM_006714487 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016235 // aggresome // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 210568_s_at BC001052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001052.1 /DEF=Homo sapiens, Similar to RecQ protein-like (DNA helicase Q1-like), clone MGC:1648, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RecQ protein-like (DNA helicaseQ1-like) /DB_XREF=gi:12654452 /UG=Hs.235069 RecQ protein-like (DNA helicase Q1-like) /FL=gb:BC001052.1 BC001052 RecQ helicase-like RECQL 5965 NM_002907 /// NM_032941 /// XM_005253461 /// XM_005253462 /// XM_005253463 /// XM_005253464 /// XM_006719133 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation 210569_s_at AF247180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF247180.1 /DEF=Homo sapiens sialic acid-binding immunoglobulin-like lectin-9 mRNA, complete cds. /FEA=mRNA /PROD=sialic acid-binding immunoglobulin-likelectin-9 /DB_XREF=gi:9392623 /UG=Hs.245828 sialic acid binding Ig-like lectin 9 /FL=gb:AF227924.1 gb:AF247180.1 AF247180 sialic acid binding Ig-like lectin 9 SIGLEC9 27180 NM_001198558 /// NM_014441 /// XM_006723146 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement 210570_x_at U35002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35002.1 /DEF=Human JNK2 beta1 protein kinase (JNK2B1) mRNA, complete cds. /FEA=mRNA /GEN=JNK2B1 /PROD=JNK2 beta1 protein kinase /DB_XREF=gi:1463132 /UG=Hs.246857 mitogen-activated protein kinase 9 /FL=gb:U35002.1 gb:U35003.1 U35002 mitogen-activated protein kinase 9 MAPK9 5601 NM_001135044 /// NM_002752 /// NM_139068 /// NM_139069 /// NM_139070 /// XM_005265940 /// XM_006714891 0000165 // MAPK cascade // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010770 // positive regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0032308 // positive regulation of prostaglandin secretion // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004705 // JUN kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 210571_s_at AF074480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF074480.1 /DEF=Homo sapiens CMP-N-acetylneuraminic acid hydroxylase mRNA, complete cds. /FEA=mRNA /PROD=CMP-N-acetylneuraminic acid hydroxylase /DB_XREF=gi:3800813 /UG=Hs.24697 cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) /FL=gb:AF074480.1 AF074480 cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene CMAHP 8418 NR_002174 /// NR_027626 0046381 // CMP-N-acetylneuraminate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030338 // CMP-N-acetylneuraminate monooxygenase activity // non-traceable author statement /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 210572_at BC003126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003126.1 /DEF=Homo sapiens, Similar to protocadherin alpha 2, clone MGC:3223, mRNA, complete cds. /FEA=mRNA /PROD=Similar to protocadherin alpha 2 /DB_XREF=gi:13111910 /UG=Hs.247741 protocadherin alpha 2 /FL=gb:BC003126.1 BC003126 protocadherin alpha 2 /// protocadherin alpha 3 PCDHA2 /// PCDHA3 56145 /// 56146 NM_018905 /// NM_018906 /// NM_031495 /// NM_031496 /// NM_031497 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 210573_s_at BC004424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004424.1 /DEF=Homo sapiens, clone MGC:3538, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3538) /DB_XREF=gi:13325209 /UG=Hs.250745 polymerase (RNA) III (DNA directed) (62kD) /FL=gb:BC004424.1 BC004424 polymerase (RNA) III (DNA directed) polypeptide C (62kD) POLR3C 10623 NM_006468 /// XM_005272927 /// XM_005272928 /// XM_005277333 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement 210574_s_at AF241788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241788.1 /DEF=Homo sapiens NPD011 (NPD011) mRNA, complete cds. /FEA=mRNA /GEN=NPD011 /PROD=NPD011 /DB_XREF=gi:12005492 /UG=Hs.263812 nuclear distribution gene C (A.nidulans) homolog /FL=gb:AF241788.1 AF241788 nudC nuclear distribution protein NUDC 10726 NM_006600 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210575_at AF241788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241788.1 /DEF=Homo sapiens NPD011 (NPD011) mRNA, complete cds. /FEA=mRNA /GEN=NPD011 /PROD=NPD011 /DB_XREF=gi:12005492 /UG=Hs.263812 nuclear distribution gene C (A.nidulans) homolog /FL=gb:AF241788.1 AF241788 nudC nuclear distribution protein NUDC 10726 NM_006600 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 210576_at AF133298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF133298.1 /DEF=Homo sapiens cytochrome P450 (CYP4F8) mRNA, complete cds. /FEA=mRNA /GEN=CYP4F8 /PROD=cytochrome P450 /DB_XREF=gi:5733408 /UG=Hs.268554 cytochrome P450, subfamily IVF, polypeptide 8 /FL=gb:NM_007253.2 gb:AF133298.1 AF133298 cytochrome P450, family 4, subfamily F, polypeptide 8 CYP4F8 11283 NM_007253 0006690 // icosanoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 210577_at U20760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20760.1 /DEF=Human extracellular calcium-sensing receptor mRNA, complete cds. /FEA=mRNA /PROD=extracellular calcium-sensing receptor /DB_XREF=gi:683746 /UG=Hs.272429 calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism) /FL=gb:U20760.1 U20760 calcium-sensing receptor CASR 846 NM_000388 /// NM_001178065 /// XM_005247836 /// XM_005247837 /// XM_006713789 /// XM_006713790 0001503 // ossification // traceable author statement /// 0002931 // response to ischemia // inferred from electronic annotation /// 0005513 // detection of calcium ion // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007635 // chemosensory behavior // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071404 // cellular response to low-density lipoprotein particle stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0019808 // polyamine binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation 210578_at AF220122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220122.1 /DEF=Homo sapiens tripartite motif protein TRIM10 alpha (TRIM10) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM10 /PROD=tripartite motif protein TRIM10 alpha /DB_XREF=gi:12407412 /UG=Hs.274295 ring finger protein 9 /FL=gb:AF220122.1 gb:NM_006778.1 AF220122 tripartite motif containing 10 TRIM10 10107 NM_006778 /// NM_052828 0030218 // erythrocyte differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210579_s_at AF220122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220122.1 /DEF=Homo sapiens tripartite motif protein TRIM10 alpha (TRIM10) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM10 /PROD=tripartite motif protein TRIM10 alpha /DB_XREF=gi:12407412 /UG=Hs.274295 ring finger protein 9 /FL=gb:AF220122.1 gb:NM_006778.1 AF220122 tripartite motif containing 10 TRIM10 10107 NM_006778 /// NM_052828 0030218 // erythrocyte differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210580_x_at L25275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L25275.1 /DEF=Human estrogen sulfotransferase mRNA, complete cds. /FEA=mRNA /PROD=estrogen sulfotransferase /DB_XREF=gi:463124 /UG=Hs.274614 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 /FL=gb:L25275.1 L25275 sulfotransferase 1A3/1A4-like /// SLX1A-SULT1A3 readthrough (NMD candidate) /// SLX1B-SULT1A4 readthrough (NMD candidate) /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 LOC101929857 /// SLX1A-SULT1A3 /// SLX1B-SULT1A4 /// SULT1A3 /// SULT1A4 6818 /// 445329 /// 100526830 /// 100526831 /// 101929857 NM_001017387 /// NM_001017389 /// NM_001017390 /// NM_001017391 /// NM_003166 /// NM_177552 /// NR_037608 /// NR_037609 /// XM_005276506 /// XM_005276507 /// XM_006726621 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004062 // aryl sulfotransferase activity // traceable author statement /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 210581_x_at AF254088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF254088.1 /DEF=Homo sapiens EWSZSG fusion protein long B isoform (EWSZSG fusion) mRNA, complete cds. /FEA=mRNA /GEN=EWSZSG fusion /PROD=EWSZSG fusion protein long B isoform /DB_XREF=gi:9954384 /UG=Hs.27801 zinc finger protein 278 /FL=gb:AF254088.1 AF254088 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210582_s_at AL117466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL117466.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586K0922 (from clone DKFZp586K0922); complete cds. /FEA=mRNA /GEN=DKFZp586K0922 /PROD=hypothetical protein /DB_XREF=gi:5911930 /UG=Hs.278027 LIM domain kinase 2 /FL=gb:AL117466.1 gb:NM_016733.1 AL117466 LIM domain kinase 2 LIMK2 3985 NM_001031801 /// NM_005569 /// NM_016733 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0042325 // regulation of phosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210583_at AB055760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB055760.1 /DEF=Homo sapiens mRNA for KIAA1649 protein, complete cds. /FEA=mRNA /GEN=KIAA1649 /PROD=KIAA1649 protein /DB_XREF=gi:13359268 /UG=Hs.278314 hypothetical protein /FL=gb:AB055760.1 AB055760 polymerase (DNA-directed), delta interacting protein 3 POLDIP3 84271 NM_001278657 /// NM_032311 /// NM_178136 /// NR_103820 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210584_s_at AB055760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB055760.1 /DEF=Homo sapiens mRNA for KIAA1649 protein, complete cds. /FEA=mRNA /GEN=KIAA1649 /PROD=KIAA1649 protein /DB_XREF=gi:13359268 /UG=Hs.278314 hypothetical protein /FL=gb:AB055760.1 AB055760 polymerase (DNA-directed), delta interacting protein 3 /// ribosomal RNA processing 7 homolog B (S. cerevisiae) POLDIP3 /// RRP7B 84271 /// 91695 NM_001278657 /// NM_032311 /// NM_178136 /// NR_002184 /// NR_103820 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210585_s_at AF007748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF007748.1 /DEF=Homo sapiens karyopherin beta2b homolog mRNA, complete cds. /FEA=mRNA /PROD=karyopherin beta2b homolog /DB_XREF=gi:2440003 /UG=Hs.278378 karyopherin beta 2b, transportin /FL=gb:AF007748.1 gb:NM_013433.1 AF007748 transportin 2 TNPO2 30000 NM_001136195 /// NM_001136196 /// NM_013433 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 210586_x_at AF312679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312679.1 /DEF=Homo sapiens rhesus D category VI type IV protein (RHD) mRNA, complete cds. /FEA=mRNA /GEN=RHD /PROD=rhesus D category VI type IV protein /DB_XREF=gi:11878260 /UG=Hs.278994 Rhesus blood group, CcEe antigens /FL=gb:AB049753.1 gb:AB049754.1 gb:NM_020485.1 gb:AF312679.1 gb:AF056965.1 gb:M34015.1 gb:AB018644.1 gb:AB018645.1 gb:AB030388.1 AF312679 Rh blood group, D antigen RHD 6007 NM_001127691 /// NM_001282867 /// NM_001282868 /// NM_001282869 /// NM_001282870 /// NM_001282871 /// NM_001282872 /// NM_016124 /// NM_016225 0015696 // ammonium transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from electronic annotation 210587_at BC005161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005161.1 /DEF=Homo sapiens, Similar to inhibin beta E, clone MGC:4638, mRNA, complete cds. /FEA=mRNA /PROD=Similar to inhibin beta E /DB_XREF=gi:13477368 /UG=Hs.279497 Homo sapiens, Similar to inhibin beta E, clone MGC:4638, mRNA, complete cds /FL=gb:BC005161.1 BC005161 inhibin, beta E INHBE 83729 NM_031479 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 210588_x_at L32610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L32610.1 /DEF=Homo sapiens ribonucleoprotein mRNA, complete cds. /FEA=mRNA /PROD=ribonucleoprotein /DB_XREF=gi:5542019 /UG=Hs.279681 heterogeneous nuclear ribonucleoprotein H3 (2H9) /FL=gb:L32610.1 L32610 heterogeneous nuclear ribonucleoprotein H3 (2H9) HNRNPH3 3189 NM_012207 /// NM_021644 /// XM_005269748 /// XM_005269749 /// XM_005269751 /// XM_005269752 /// XM_005269753 /// XM_005269754 /// XM_006717816 /// XM_006717817 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210589_s_at D13287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13287.1 /DEF=Human mRNA for alternative splicing product of glucocerebrosidase pseudogene, complete cds. /FEA=mRNA /PROD=glucocerebrosidase /DB_XREF=gi:496370 /UG=Hs.282997 glucosidase, beta; acid (includes glucosylceramidase) /FL=gb:D13287.1 D13287 glucosidase, beta, acid pseudogene 1 GBAP1 2630 NR_002188 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006680 // glucosylceramide catabolic process // inferred from mutant phenotype /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046512 // sphingosine biosynthetic process // inferred from mutant phenotype /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004348 // glucosylceramidase activity // inferred from direct assay /// 0004348 // glucosylceramidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 210592_s_at M55580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55580.1 /DEF=Human spermidinespermine N1-acetyltransferase mRNA, complete cds. /FEA=mRNA /GEN=spermidinespermine N1-acetyltransferase /PROD=spermidinespermine N1-acetyltransferase /DB_XREF=gi:338335 /UG=Hs.28491 spermidinespermine N1-acetyltransferase /FL=gb:M55580.1 M55580 spermidine/spermine N1-acetyltransferase 1 SAT1 6303 NM_002970 /// NR_027783 0001525 // angiogenesis // inferred from expression pattern /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009447 // putrescine catabolic process // inferred from electronic annotation /// 0032918 // spermidine acetylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004145 // diamine N-acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019809 // spermidine binding // inferred from electronic annotation 210593_at M55580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55580.1 /DEF=Human spermidinespermine N1-acetyltransferase mRNA, complete cds. /FEA=mRNA /GEN=spermidinespermine N1-acetyltransferase /PROD=spermidinespermine N1-acetyltransferase /DB_XREF=gi:338335 /UG=Hs.28491 spermidinespermine N1-acetyltransferase /FL=gb:M55580.1 M55580 spermidine/spermine N1-acetyltransferase 1 /// zinc finger, SWIM-type containing 8 SAT1 /// ZSWIM8 6303 /// 23053 NM_001242487 /// NM_001242488 /// NM_002970 /// NM_015037 /// NR_027783 /// XM_005269648 /// XM_005269649 /// XM_005269651 /// XM_005269652 /// XM_005269653 /// XM_005269655 /// XM_006717725 0001525 // angiogenesis // inferred from expression pattern /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009447 // putrescine catabolic process // inferred from electronic annotation /// 0032918 // spermidine acetylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004145 // diamine N-acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019809 // spermidine binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210594_x_at AF239756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF239756.1 /DEF=Homo sapiens PZR1b mRNA, complete cds. /FEA=mRNA /PROD=PZR1b /DB_XREF=gi:7542562 /UG=Hs.287832 myelin protein zero-like 1 /FL=gb:AF239756.1 AF239756 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210595_at BC002663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002663.1 /DEF=Homo sapiens, Similar to zinc finger protein homologous to mouse Zfp93, clone MGC:3594, mRNA, complete cds. /FEA=mRNA /PROD=Similar to zinc finger protein homologous tomouse Zfp93 /DB_XREF=gi:12803656 /UG=Hs.298089 zinc finger protein homologous to Zfp93 in mouse /FL=gb:BC002663.1 gb:BC002800.1 BC002663 zinc finger protein 235 ZNF235 9310 NM_004234 /// XM_005259412 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 210596_at AF130104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130104.1 /DEF=Homo sapiens clone FLB3024 PRO0756 mRNA, complete cds. /FEA=mRNA /PROD=PRO0756 /DB_XREF=gi:11493511 /UG=Hs.305979 Homo sapiens clone FLB3024 PRO0756 mRNA, complete cds /FL=gb:AF130104.1 AF130104 magnesium transporter 1 MAGT1 84061 NM_032121 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype 210597_x_at K03206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03206.1 /DEF=Human PRB1 locus salivary proline-rich protein mRNA, clone cP5, complete cds. /FEA=mRNA /GEN=PRB1 /DB_XREF=gi:190505 /UG=Hs.306948 Human PRB1 locus salivary proline-rich protein mRNA, clone cP5, complete cds /FL=gb:K03206.1 K03206 proline-rich protein BstNI subfamily 1 PRB1 5542 NM_005039 /// NM_199353 /// NM_199354 0005576 // extracellular region // inferred from electronic annotation 210598_at AF130051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130051.1 /DEF=Homo sapiens clone FLB3535 PRO0898 mRNA, complete cds. /FEA=mRNA /PROD=PRO0898 /DB_XREF=gi:11493408 /UG=Hs.306960 Homo sapiens clone FLB3535 PRO0898 mRNA, complete cds /FL=gb:AF130051.1 AF130051 210599_at BC004930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004930.1 /DEF=Homo sapiens, Similar to KIAA0798 gene product, clone MGC:10546, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0798 gene product /DB_XREF=gi:13436262 /UG=Hs.326742 Homo sapiens, Similar to KIAA0798 gene product, clone MGC:10546, mRNA, complete cds /FL=gb:BC004930.1 BC004930 zinc finger protein 614 ZNF614 80110 NM_025040 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210600_s_at U33054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U33054.1 /DEF=Human G protein-coupled receptor kinase GRK4 mRNA, alpha splice variant, complete cds. /FEA=mRNA /PROD=G protein-coupled receptor kinase GRK4, alphasplice variant /DB_XREF=gi:971254 /UG=Hs.32959 G protein-coupled receptor kinase 2 (Drosophila)-like /FL=gb:U33054.1 U33054 G protein-coupled receptor kinase 4 GRK4 2868 NM_001004056 /// NM_001004057 /// NM_005307 /// NM_182982 /// XM_005247957 /// XM_005247959 /// XM_005247960 /// XM_005247961 /// XM_005247962 /// XM_005247963 /// XM_006713879 /// XM_006713880 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050254 // rhodopsin kinase activity // inferred from electronic annotation 210601_at BC000019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000019.1 /DEF=Homo sapiens, Similar to cadherin 6, type 2, K-cadherin (fetal kidney), clone MGC:1470, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cadherin 6, type 2, K-cadherin (fetalkidney) /DB_XREF=gi:12652558 /UG=Hs.32963 cadherin 6, type 2, K-cadherin (fetal kidney) /FL=gb:BC000019.1 BC000019 cadherin 6, type 2, K-cadherin (fetal kidney) CDH6 1004 NM_004932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210602_s_at BC000019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000019.1 /DEF=Homo sapiens, Similar to cadherin 6, type 2, K-cadherin (fetal kidney), clone MGC:1470, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cadherin 6, type 2, K-cadherin (fetalkidney) /DB_XREF=gi:12652558 /UG=Hs.32963 cadherin 6, type 2, K-cadherin (fetal kidney) /FL=gb:BC000019.1 BC000019 cadherin 6, type 2, K-cadherin (fetal kidney) CDH6 1004 NM_004932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210603_at BC004552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004552.1 /DEF=Homo sapiens, clone MGC:10646, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10646) /DB_XREF=gi:13528710 /UG=Hs.330986 Homo sapiens, clone MGC:10646, mRNA, complete cds /FL=gb:BC004552.1 BC004552 N(alpha)-acetyltransferase 11, NatA catalytic subunit NAA11 84779 NM_032693 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0031415 // NatA complex // inferred from direct assay 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 210604_at BC000233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000233.1 /DEF=Homo sapiens, Similar to guanine nucleotide binding protein, alpha transducing 2, clone MGC:2232, mRNA, complete cds. /FEA=mRNA /PROD=Similar to guanine nucleotide binding protein,alpha transducing 2 /DB_XREF=gi:12652948 /UG=Hs.36973 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 /FL=gb:BC000233.1 BC000233 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 GNAT2 2780 NM_005272 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007601 // visual perception // non-traceable author statement /// 0007602 // phototransduction // non-traceable author statement /// 0009642 // response to light intensity // inferred from electronic annotation /// 0046549 // retinal cone cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042622 // photoreceptor outer segment membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // non-traceable author statement /// 0008020 // G-protein coupled photoreceptor activity // non-traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 210605_s_at BC003610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003610.1 /DEF=Homo sapiens, Similar to milk fat globule-EGF factor 8 protein, clone MGC:1373, mRNA, complete cds. /FEA=mRNA /PROD=Similar to milk fat globule-EGF factor 8protein /DB_XREF=gi:13177647 /UG=Hs.3745 milk fat globule-EGF factor 8 protein /FL=gb:BC003610.1 BC003610 milk fat globule-EGF factor 8 protein MFGE8 4240 NM_001114614 /// NM_005928 /// XM_005254920 /// XM_005254921 0001525 // angiogenesis // inferred from electronic annotation /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 2000427 // positive regulation of apoptotic cell clearance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from electronic annotation 210606_x_at U30610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U30610.1 /DEF=Human CD94 protein mRNA, complete cds. /FEA=mRNA /PROD=CD94 protein /DB_XREF=gi:1098616 /UG=Hs.41682 killer cell lectin-like receptor subfamily D, member 1 /FL=gb:U30610.1 gb:NM_002262.2 U30610 killer cell lectin-like receptor subfamily D, member 1 KLRD1 3824 NM_001114396 /// NM_002262 /// NM_007334 /// XM_005253363 /// XM_006719065 /// XM_006719066 /// XM_006719067 /// XM_006719068 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 210607_at U03858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03858.1 /DEF=Human flt3 ligand mRNA, complete cds. /FEA=mRNA /PROD=flt3 ligand /DB_XREF=gi:494978 /UG=Hs.428 fms-related tyrosine kinase 3 ligand /FL=gb:U03858.1 U03858 fms-related tyrosine kinase 3 ligand FLT3LG 2323 NM_001204502 /// NM_001204503 /// NM_001278637 /// NM_001278638 /// NM_001459 /// XM_005258680 /// XM_005258681 /// XM_005258682 /// XM_005258683 /// XM_005258684 /// XM_005258685 /// XM_006723114 /// XM_006723115 /// XM_006723116 /// XM_006723117 /// XM_006723118 0007165 // signal transduction // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0031233 // intrinsic component of external side of plasma membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 210608_s_at BC001899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001899.1 /DEF=Homo sapiens, Similar to fucosyltransferase 2 (secretor status included), clone MGC:2062, mRNA, complete cds. /FEA=mRNA /PROD=Similar to fucosyltransferase 2 (secretor statusincluded) /DB_XREF=gi:12804894 /UG=Hs.46328 fucosyltransferase 2 (secretor status included) /FL=gb:BC001899.1 BC001899 fucosyltransferase 2 (secretor status included) FUT2 2524 NM_000511 /// NM_001097638 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // traceable author statement /// 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210609_s_at BC000474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000474.1 /DEF=Homo sapiens, quinone oxidoreductase homolog, clone MGC:8642, mRNA, complete cds. /FEA=mRNA /PROD=quinone oxidoreductase homolog /DB_XREF=gi:12653408 /UG=Hs.50649 quinone oxidoreductase homolog /FL=gb:BC000474.1 BC000474 tumor protein p53 inducible protein 3 TP53I3 9540 NM_001206802 /// NM_004881 /// NM_147184 /// XM_005264650 /// XM_006712150 0006739 // NADP metabolic process // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0003960 // NADPH:quinone reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048038 // quinone binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from direct assay 210610_at M69176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M69176.1 /DEF=Human biliary glycoprotein mRNA, complete cds. /FEA=mRNA /GEN=BGP /PROD=biliary glycoprotein a /DB_XREF=gi:179434 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:M69176.1 M69176 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) CEACAM1 634 NM_001024912 /// NM_001184813 /// NM_001184815 /// NM_001184816 /// NM_001205344 /// NM_001712 0001525 // angiogenesis // non-traceable author statement /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 210611_s_at U26744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U26744.1 /DEF=Human dystrobrevin-gamma mRNA, complete cds. /FEA=mRNA /PROD=dystrobrevin-gamma /DB_XREF=gi:1255992 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:U26744.1 U26744 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210612_s_at AF318616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF318616.1 /DEF=Homo sapiens synaptojanin 2 mRNA, complete cds. /FEA=mRNA /PROD=synaptojanin 2 /DB_XREF=gi:12034891 /UG=Hs.61289 synaptojanin 2 /FL=gb:AF318616.1 AF318616 synaptojanin 2 SYNJ2 8871 NM_001178088 /// NM_003898 /// XM_005267197 /// XM_005267198 /// XM_005267199 /// XM_005267200 /// XM_006715591 /// XM_006715592 /// XR_245556 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 210613_s_at BC000731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000731.1 /DEF=Homo sapiens, synaptogyrin 1, clone MGC:1939, mRNA, complete cds. /FEA=mRNA /PROD=synaptogyrin 1 /DB_XREF=gi:12653878 /UG=Hs.6139 synaptogyrin 1 /FL=gb:BC000731.1 BC000731 synaptogyrin 1 SYNGR1 9145 NM_004711 /// NM_145731 /// NM_145738 0006605 // protein targeting // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 210614_at U21938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U21938.1 /DEF=Human alpha-tocopherol transfer protein mRNA, complete cds. /FEA=mRNA /PROD=alpha-tocopherol transfer protein /DB_XREF=gi:726181 /UG=Hs.69049 tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) /FL=gb:NM_000370.1 gb:D49488.1 gb:U21938.1 U21938 tocopherol (alpha) transfer protein TTPA 7274 NM_000370 /// XM_006716468 0001890 // placenta development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0032502 // developmental process // inferred from electronic annotation /// 0042360 // vitamin E metabolic process // inferred from electronic annotation /// 0046909 // intermembrane transport // inferred from sequence or structural similarity /// 0051180 // vitamin transport // inferred from sequence or structural similarity /// 0051452 // intracellular pH reduction // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0090212 // negative regulation of establishment of blood-brain barrier // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0008431 // vitamin E binding // inferred from sequence or structural similarity /// 0019842 // vitamin binding // inferred from electronic annotation /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from sequence or structural similarity 210615_at AF280547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280547.1 /DEF=Homo sapiens neuropilin-1 soluble isoform 11 (NRP1) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=NRP1 /PROD=neuropilin-1 soluble isoform 11 /DB_XREF=gi:11907931 /UG=Hs.69285 neuropilin 1 /FL=gb:AF280547.1 AF280547 neuropilin 1 NRP1 8829 NM_001024628 /// NM_001024629 /// NM_001244972 /// NM_001244973 /// NM_003873 /// NR_045259 /// XM_006717521 /// XM_006717522 /// XM_006717523 /// XM_006717524 /// XM_006717525 /// XM_006717526 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021636 // trigeminal nerve morphogenesis // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from mutant phenotype /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048841 // regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0060301 // positive regulation of cytokine activity // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from sequence or structural similarity /// 0060627 // regulation of vesicle-mediated transport // traceable author statement /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0060978 // angiogenesis involved in coronary vascular morphogenesis // inferred from sequence or structural similarity /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // non-traceable author statement /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0097102 // endothelial tip cell fate specification // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1901166 // neural crest cell migration involved in autonomic nervous system development // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902946 // protein localization to early endosome // inferred from sequence or structural similarity /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005883 // neurofilament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // traceable author statement /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0015026 // coreceptor activity // traceable author statement /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210616_s_at AB020712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB020712.1 /DEF=Homo sapiens mRNA for KIAA0905 protein, complete cds. /FEA=mRNA /GEN=KIAA0905 /PROD=KIAA0905 protein /DB_XREF=gi:4240298 /UG=Hs.70266 yeast Sec31p homolog /FL=gb:AB020712.1 AB020712 SEC31 homolog A (S. cerevisiae) SEC31A 22872 NM_001077206 /// NM_001077207 /// NM_001077208 /// NM_001191049 /// NM_014933 /// NM_016211 /// XM_005262847 /// XM_005262849 /// XM_005262850 /// XM_005262851 /// XM_005262852 /// XM_005262854 /// XM_006714141 /// XM_006714142 /// XM_006714143 /// XM_006714144 /// XM_006714145 /// XM_006714146 /// XM_006714147 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030120 // vesicle coat // inferred from direct assay /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210617_at U87284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87284.1 /DEF=Human phosphate regulating neutral endopeptidase (PEX) mRNA, complete cds. /FEA=mRNA /GEN=PEX /PROD=phosphate regulating neutral endopeptidase /DB_XREF=gi:1842089 /UG=Hs.72874 phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) /FL=gb:NM_000444.1 gb:U87284.1 gb:U75645.1 gb:AD000712.1 U87284 phosphate regulating endopeptidase homolog, X-linked PHEX 5251 NM_000444 /// NM_001282754 0001501 // skeletal system development // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0019637 // organophosphate metabolic process // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210618_at AB007943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007943.1 /DEF=Homo sapiens mRNA for KIAA0474 protein, complete cds. /FEA=mRNA /GEN=KIAA0474 /PROD=KIAA0474 protein /DB_XREF=gi:3413909 /UG=Hs.75151 RAP1, GTPase activating protein 1 /FL=gb:AB007943.1 AB007943 RAP1 GTPase activating protein RAP1GAP 5909 NM_001145657 /// NM_001145658 /// NM_002885 /// XM_005245954 /// XM_005245955 /// XM_005245956 /// XM_006710804 /// XM_006710805 /// XM_006710806 /// XM_006710807 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0032318 // regulation of Ras GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003924 // GTPase activity // non-traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046582 // Rap GTPase activator activity // inferred from direct assay 210619_s_at AF173154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF173154.1 /DEF=Homo sapiens hyaluronoglucosaminidase 1 isoform 2 (HYAL1) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=HYAL1 /PROD=hyaluronoglucosaminidase 1 isoform 2 /DB_XREF=gi:5825510 /UG=Hs.75619 hyaluronoglucosaminidase 1 /FL=gb:AF118821.1 gb:AF173154.1 AF173154 hyaluronoglucosaminidase 1 HYAL1 3373 NM_033159 /// NM_153281 /// NM_153282 /// NM_153283 /// NM_153284 /// NM_153285 /// NM_153286 /// NR_047690 0000302 // response to reactive oxygen species // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from direct assay /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030213 // hyaluronan biosynthetic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0036120 // cellular response to platelet-derived growth factor stimulus // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045927 // positive regulation of growth // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051216 // cartilage development // inferred from expression pattern /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071467 // cellular response to pH // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay /// 1900106 // positive regulation of hyaluranon cable assembly // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0036117 // hyaluranon cable // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0050501 // hyaluronan synthase activity // inferred from direct assay 210620_s_at BC000212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000212.1 /DEF=Homo sapiens, Similar to general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD), clone MGC:1731, mRNA, complete cds. /FEA=mRNA /PROD=Similar to general transcription factor IIIC,polypeptide 2 (beta subunit, 110kD) /DB_XREF=gi:12652912 /UG=Hs.75782 general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) /FL=gb:BC000212.1 BC000212 general transcription factor IIIC, polypeptide 2, beta 110kDa GTF3C2 2976 NM_001035521 /// NM_001521 /// XM_005264272 /// XM_005264273 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 210621_s_at M23612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M23612.1 /DEF=Human GTPase-activating protein (GAP) mRNA, complete cds. /FEA=mRNA /GEN=GAP /PROD=GTPase-activating protein /DB_XREF=gi:182973 /UG=Hs.758 RAS p21 protein activator (GTPase activating protein) 1 /FL=gb:NM_022650.1 gb:M23612.1 M23612 RAS p21 protein activator (GTPase activating protein) 1 RASA1 5921 NM_002890 /// NM_022650 0000281 // mitotic cytokinesis // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0008360 // regulation of cell shape // non-traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051252 // regulation of RNA metabolic process // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0001948 // glycoprotein binding // inferred from physical interaction /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019870 // potassium channel inhibitor activity // non-traceable author statement /// 0051020 // GTPase binding // inferred from physical interaction 210622_x_at AF153430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153430.1 /DEF=Homo sapiens cyclin-dependent kinase related protein (CDK10) mRNA, splice variant, complete cds. /FEA=mRNA /GEN=CDK10 /PROD=cyclin-dependent kinase related protein /DB_XREF=gi:6580936 /UG=Hs.77313 cyclin-dependent kinase (CDC2-like) 10 /FL=gb:AF153430.1 AF153430 cyclin-dependent kinase 10 CDK10 8558 NM_001098533 /// NM_001160367 /// NM_003674 /// NM_052987 /// NM_052988 /// NR_027702 /// NR_027703 /// XM_006721308 /// XM_006721309 /// XM_006721310 /// XM_006721311 /// XM_006721312 /// XM_006721313 /// XM_006721314 /// XM_006721315 /// XM_006721316 /// XM_006721317 /// XM_006721318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210623_at BC001372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001372.1 /DEF=Homo sapiens, Similar to ORF, clone MGC:2274, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ORF /DB_XREF=gi:12655044 /UG=Hs.77868 ORF /FL=gb:BC001372.1 BC001372 UBX domain protein 1 UBXN1 51035 NM_001286077 /// NM_001286078 /// NM_015853 /// XM_005274033 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction /// 0071796 // K6-linked polyubiquitin binding // inferred from direct assay 210624_s_at BC000109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000109.1 /DEF=Homo sapiens, Similar to ilvB (bacterial acetolactate synthase)-like, clone MGC:1269, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ilvB (bacterial acetolactatesynthase)-like /DB_XREF=gi:12652718 /UG=Hs.78880 ilvB (bacterial acetolactate synthase)-like /FL=gb:BC000109.1 BC000109 ilvB (bacterial acetolactate synthase)-like ILVBL 10994 NM_006844 /// NM_176826 /// XM_005259717 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210625_s_at U34074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34074.1 /DEF=Human A kinase anchor protein S-AKAP84 mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=S-AKAP84 /DB_XREF=gi:1049216 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:U34074.1 U34074 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210626_at U34074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34074.1 /DEF=Human A kinase anchor protein S-AKAP84 mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=S-AKAP84 /DB_XREF=gi:1049216 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:U34074.1 U34074 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210627_s_at BC002804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002804.1 /DEF=Homo sapiens, Similar to glucosidase I, clone MGC:3544, mRNA, complete cds. /FEA=mRNA /PROD=Similar to glucosidase I /DB_XREF=gi:12803914 /UG=Hs.83919 glucosidase I /FL=gb:BC002804.1 BC002804 mannosyl-oligosaccharide glucosidase MOGS 7841 NM_001146158 /// NM_006302 0006457 // protein folding // traceable author statement /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004573 // mannosyl-oligosaccharide glucosidase activity // inferred from electronic annotation /// 0015926 // glucosidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 210628_x_at AF051344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051344.1 /DEF=Homo sapiens latent transforming growth factor-beta binding protein 4S mRNA, complete cds. /FEA=mRNA /PROD=latent transforming growth factor-beta bindingprotein 4S /DB_XREF=gi:3327807 /UG=Hs.85087 latent transforming growth factor beta binding protein 4 /FL=gb:AF051344.1 AF051344 latent transforming growth factor beta binding protein 4 LTBP4 8425 NM_001042544 /// NM_001042545 /// NM_003573 0001558 // regulation of cell growth // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016049 // cell growth // traceable author statement /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030162 // regulation of proteolysis // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030252 // growth hormone secretion // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0046879 // hormone secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // non-traceable author statement /// 0008083 // growth factor activity // non-traceable author statement /// 0008083 // growth factor activity // traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 210629_x_at AF000425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000425.1 /DEF=Homo sapiens LST1 mRNA, cLST1A splice variant, complete cds. /FEA=mRNA /GEN=LST1 /DB_XREF=gi:2145065 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF000425.1 AF000425 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 210630_s_at AF125949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125949.1 /DEF=Homo sapiens DNA repair protein RAD52 gamma isoform (RAD52) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=RAD52 /PROD=DNA repair protein RAD52 gamma isoform /DB_XREF=gi:4581007 /UG=Hs.89571 RAD52 (S. cerevisiae) homolog /FL=gb:AF125949.1 AF125949 RAD52 homolog (S. cerevisiae) RAD52 5893 NM_001297419 /// NM_001297420 /// NM_001297421 /// NM_001297422 /// NM_134422 /// NM_134423 /// NM_134424 /// NR_123713 /// XM_005253720 /// XM_005253721 /// XM_005253725 /// XM_005253727 /// XM_006718995 /// XM_006718996 /// XM_006718997 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from mutant phenotype /// 0006312 // mitotic recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 210631_at D42072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D42072.1 /DEF=Human mRNA for NF1 N-isoform-exon11, complete cds. /FEA=mRNA /GEN=NF1 /PROD=NF1 N-isoform-exon11 /DB_XREF=gi:1060900 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:D42072.1 D42072 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 210632_s_at L35853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L35853.1 /DEF=Homo sapiens adhalin-35 mRNA, complete cds. /FEA=mRNA /PROD=adhalin-35 /DB_XREF=gi:557730 /UG=Hs.99931 sarcoglycan, alpha (50kD dystrophin-associated glycoprotein) /FL=gb:L35853.1 L35853 sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) SGCA 6442 NM_000023 /// NM_001135697 /// XM_005257574 /// XM_006722014 0006936 // muscle contraction // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 210633_x_at M19156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M19156.1 /DEF=Human acidic keratin-10 mRNA, complete cds. /FEA=mRNA /GEN=KRT10 /DB_XREF=gi:186769 /UG=Hs.99936 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) /FL=gb:M19156.1 M19156 keratin 10 KRT10 3858 NM_000421 /// XM_005257343 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0030280 // structural constituent of epidermis // non-traceable author statement 210634_at BC005253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005253.1 /DEF=Homo sapiens, Similar to Kelch motif containing protein, clone MGC:12288, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Kelch motif containing protein /DB_XREF=gi:13528917 /UG=Hs.106290 Kelch motif containing protein /FL=gb:BC005253.1 BC005253 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 210635_s_at BC005253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005253.1 /DEF=Homo sapiens, Similar to Kelch motif containing protein, clone MGC:12288, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Kelch motif containing protein /DB_XREF=gi:13528917 /UG=Hs.106290 Kelch motif containing protein /FL=gb:BC005253.1 BC005253 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 210636_at BC002715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002715.1 /DEF=Homo sapiens, Similar to peroxisome proliferative activated receptor, delta, clone MGC:3931, mRNA, complete cds. /FEA=mRNA /PROD=Similar to peroxisome proliferative activatedreceptor, delta /DB_XREF=gi:12803754 /UG=Hs.106415 peroxisome proliferative activated receptor, delta /FL=gb:BC002715.1 BC002715 peroxisome proliferator-activated receptor delta PPARD 5467 NM_001171818 /// NM_001171819 /// NM_001171820 /// NM_006238 /// NM_177435 /// XM_005249193 /// XM_005249194 /// XM_006715120 /// XM_006715121 /// XM_006715122 /// XM_006715123 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006776 // vitamin A metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // traceable author statement /// 0009299 // mRNA transcription // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0015908 // fatty acid transport // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032966 // negative regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // non-traceable author statement /// 0045684 // positive regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046697 // decidualization // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051546 // keratinocyte migration // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005504 // fatty acid binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation /// 0070539 // linoleic acid binding // inferred from direct assay 210637_at M81797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81797.1 /DEF=Human NK-1 receptor mRNA, complete cds. /FEA=mRNA /GEN=TAC1R /PROD=NK-1 receptor /DB_XREF=gi:189213 /UG=Hs.1080 tachykinin receptor 1 /FL=gb:M81797.1 gb:M76675.1 gb:M84425.1 gb:NM_001058.2 M81797 tachykinin receptor 1 TACR1 6869 NM_001058 /// NM_015727 0002118 // aggressive behavior // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0003051 // angiotensin-mediated drinking behavior // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007638 // mechanosensory behavior // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0010193 // response to ozone // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035106 // operant conditioning // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046878 // positive regulation of saliva secretion // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016496 // substance P receptor activity // inferred from electronic annotation 210638_s_at AF176704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF176704.1 /DEF=Homo sapiens F-box protein FBX9 mRNA, complete cds. /FEA=mRNA /PROD=F-box protein FBX9 /DB_XREF=gi:6103646 /UG=Hs.11050 F-box only protein 9 /FL=gb:AF176704.1 AF176704 F-box protein 9 FBXO9 26268 NM_012347 /// NM_033480 /// NM_033481 /// XM_005248995 /// XM_005248996 /// XM_006715050 /// XM_006715051 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210639_s_at AF293841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF293841.1 /DEF=Homo sapiens apoptosis-related protein (APG5L) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=APG5L /PROD=apoptosis-related protein /DB_XREF=gi:12006863 /UG=Hs.11171 APG5 (autophagy 5, S. cerevisiae)-like /FL=gb:AF293841.1 AF293841 autophagy related 5 ATG5 9474 NM_001286106 /// NM_001286107 /// NM_001286108 /// NM_001286111 /// NM_004849 /// NR_104402 /// NR_104403 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // not recorded /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002739 // regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // not recorded /// 0006914 // autophagy // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0030435 // sporulation resulting in formation of a cellular spore // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from sequence or structural similarity /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // traceable author statement /// 0048840 // otolith development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // not recorded 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // not recorded 210640_s_at U63917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63917.1 /DEF=Human G protein coupled receptor (GPCR-Br) mRNA, complete cds. /FEA=mRNA /GEN=GPCR-Br /PROD=G-protein coupled receptor /DB_XREF=gi:2656120 /UG=Hs.113207 G protein-coupled receptor 30 /FL=gb:U63917.1 U63917 G protein-coupled estrogen receptor 1 GPER1 2852 NM_001031682 /// NM_001039966 /// NM_001098201 /// NM_001505 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001956 // positive regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002695 // negative regulation of leukocyte activation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from sequence or structural similarity /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031959 // mineralocorticoid receptor signaling pathway // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051053 // negative regulation of DNA metabolic process // inferred from sequence or structural similarity /// 0051055 // negative regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from direct assay /// 0071389 // cellular response to mineralocorticoid stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0032591 // dendritic spine membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0043679 // axon terminus // inferred from sequence or structural similarity /// 0044327 // dendritic spine head // inferred from sequence or structural similarity /// 0045095 // keratin filament // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048786 // presynaptic active zone // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017082 // mineralocorticoid receptor activity // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay 210641_at AB038463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB038463.1 /DEF=Homo sapiens GC36 mRNA, complete cds. /FEA=mRNA /GEN=GC36 /DB_XREF=gi:7023942 /UG=Hs.113292 calpain 9 (nCL-4) /FL=gb:AB038463.1 AB038463 calpain 9 CAPN9 10753 NM_006615 /// NM_016452 /// XM_005273010 /// XR_426915 0006508 // proteolysis // not recorded /// 0007586 // digestion // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210642_at AF333334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF333334.1 /DEF=Homo sapiens calicin mRNA, complete cds. /FEA=mRNA /PROD=calicin /DB_XREF=gi:13377623 /UG=Hs.115460 calicin /FL=gb:AF333334.1 AF333334 calicin CCIN 881 NM_005893 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0033150 // cytoskeletal calyx // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210643_at AF053712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053712.1 /DEF=Homo sapiens osteoprotegerin ligand mRNA, complete cds. /FEA=mRNA /PROD=osteoprotegerin ligand /DB_XREF=gi:3057145 /UG=Hs.115770 tumor necrosis factor (ligand) superfamily, member 11 /FL=gb:AF019047.1 gb:AF053712.1 AF053712 tumor necrosis factor (ligand) superfamily, member 11 TNFSF11 8600 NM_003701 /// NM_033012 0001503 // ossification // inferred from electronic annotation /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0030316 // osteoclast differentiation // non-traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045453 // bone resorption // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045780 // positive regulation of bone resorption // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051466 // positive regulation of corticotropin-releasing hormone secretion // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071812 // positive regulation of fever generation by positive regulation of prostaglandin secretion // inferred from sequence or structural similarity /// 0071847 // TNFSF11-mediated signaling pathway // inferred from direct assay /// 0071848 // positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling // inferred from direct assay /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // non-traceable author statement /// 0005164 // tumor necrosis factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred by curator 210644_s_at AF109683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109683.1 /DEF=Homo sapiens leukocyte-associated Ig-like receptor 1b mRNA, complete cds. /FEA=mRNA /PROD=leukocyte-associated Ig-like receptor 1b /DB_XREF=gi:6563041 /UG=Hs.115808 leukocyte-associated Ig-like receptor 1 /FL=gb:AF251509.2 gb:NM_021706.1 gb:AF109683.1 AF109683 leukocyte-associated immunoglobulin-like receptor 1 LAIR1 3903 NM_001289023 /// NM_001289025 /// NM_001289026 /// NM_001289027 /// NM_002287 /// NM_021706 /// NM_021708 /// NR_110279 /// NR_110280 /// XM_005258920 /// XM_005258924 /// XM_005277109 /// XM_005277111 /// XM_005277309 /// XM_006726158 0002376 // immune system process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210645_s_at D83077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D83077.1 /DEF=Homo sapiens mRNA for TPRD, complete cds. /FEA=mRNA /PROD=TPRD /DB_XREF=gi:1304131 /UG=Hs.118174 tetratricopeptide repeat domain 3 /FL=gb:D83077.1 D83077 tetratricopeptide repeat domain 3 /// tetratricopeptide repeat domain 3 pseudogene 1 TTC3 /// TTC3P1 7267 /// 286495 NM_001001894 /// NM_003316 /// NR_030737 /// XM_005261045 /// XM_005261046 /// XM_005261047 /// XM_005261048 /// XM_005261049 /// XM_005261050 /// XM_005261051 /// XM_005261052 /// XM_005261053 /// XM_005261054 /// XM_005261055 /// XM_005261056 /// XM_005261058 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0010771 // negative regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210646_x_at BC001675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001675.1 /DEF=Homo sapiens, ribosomal protein L13a, clone MGC:2546, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L13a /DB_XREF=gi:12804528 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC001675.1 gb:BC001836.1 BC001675 ribosomal protein L13a /// ribosomal protein L13a pseudogene 5 /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A RPL13A /// RPL13AP5 /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 /// 728658 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_026712 /// NR_073024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 210647_x_at AF102988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF102988.1 /DEF=Homo sapiens Ca2+-independent phospholipase A2 short isoform (iPLA2) mRNA, complete cds. /FEA=mRNA /GEN=iPLA2 /PROD=Ca2+-independent phospholipase A2 short isoform /DB_XREF=gi:5305593 /UG=Hs.120360 phospholipase A2, group VI (cytosolic, calcium-independent) /FL=gb:AF102988.1 AF102988 phospholipase A2, group VI (cytosolic, calcium-independent) PLA2G6 8398 NM_001004426 /// NM_001199562 /// NM_003560 /// XM_005261764 /// XM_005261765 /// XM_005261766 /// XM_005261771 /// XM_006724332 /// XR_244390 /// XR_244392 /// XR_430411 /// XR_430412 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090238 // positive regulation of arachidonic acid secretion // inferred from electronic annotation /// 1901339 // regulation of store-operated calcium channel activity // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from electronic annotation 210648_x_at AB047360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB047360.1 /DEF=Homo sapiens SNX 3A mRNA for sorting nexin 3A, complete cds. /FEA=mRNA /GEN=SNX 3A /PROD=sorting nexin 3A /DB_XREF=gi:12957159 /UG=Hs.12102 sorting nexin 3 /FL=gb:AB047360.1 AB047360 sorting nexin 3 SNX3 8724 NM_003795 /// NM_152827 /// NM_152828 /// XM_005267192 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 210649_s_at AF231056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF231056.1 /DEF=Homo sapiens BRG1-Associated Factor 250a (BAF250a) mRNA, complete cds. /FEA=mRNA /GEN=BAF250a /PROD=BRG1-Associated Factor 250a /DB_XREF=gi:11320941 /UG=Hs.123090 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 /FL=gb:AF231056.1 AF231056 AT rich interactive domain 1A (SWI-like) ARID1A 8289 NM_006015 /// NM_018450 /// NM_139135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003205 // cardiac chamber development // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0042766 // nucleosome mobilization // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0090544 // BAF-type complex // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from electronic annotation 210650_s_at BC001304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001304.1 /DEF=Homo sapiens, Similar to aczonin, clone MGC:5486, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aczonin /DB_XREF=gi:12654916 /UG=Hs.12376 piccolo (presynaptic cytomatrix protein) /FL=gb:BC001304.1 BC001304 piccolo presynaptic cytomatrix protein PCLO 27445 NM_014510 /// NM_033026 /// XM_006715926 0006810 // transport // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // non-traceable author statement /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005856 // cytoskeleton // non-traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from sequence or structural similarity /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210651_s_at L41939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L41939.1 /DEF=Homo sapiens (clone FBK III 11c) protein-tyrosine kinase (DRT) mRNA, complete cds. /FEA=mRNA /GEN=DRT /PROD=protein-tyrosine kinase /DB_XREF=gi:1100109 /UG=Hs.125124 EphB2 /FL=gb:L41939.1 L41939 EPH receptor B2 EPHB2 2048 NM_004442 /// NM_017449 /// XM_006710441 /// XM_006710442 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007612 // learning // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210652_s_at BC004399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004399.1 /DEF=Homo sapiens, clone MGC:10985, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10985) /DB_XREF=gi:13325163 /UG=Hs.125783 DEME-6 protein /FL=gb:BC004399.1 BC004399 tetratricopeptide repeat domain 39A TTC39A 22996 NM_001080494 /// NM_001144832 /// XM_005270641 /// XM_005270643 /// XM_005270644 /// XM_005270645 /// XM_005270646 /// XM_006710471 0005515 // protein binding // inferred from electronic annotation 210653_s_at M55575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M55575.1 /DEF=Human branched chain alpha-keto acid dehydrogenase (BCKDHB) E1-beta subunit mRNA, complete cds. /FEA=mRNA /GEN=BCKDHB /PROD=branched chain alpha-keto acid dehydrogenaseE1-beta subunit /DB_XREF=gi:179361 /UG=Hs.1265 branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) /FL=gb:M55575.1 M55575 branched chain keto acid dehydrogenase E1, beta polypeptide BCKDHB 594 NM_000056 /// NM_183050 /// XM_005248756 /// XM_006715542 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // inferred from mutant phenotype /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from mutant phenotype /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from mutant phenotype 0003824 // catalytic activity // inferred from electronic annotation /// 0003826 // alpha-ketoacid dehydrogenase activity // inferred from electronic annotation /// 0003863 // 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation 210654_at AF021233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF021233.1 /DEF=Homo sapiens TRAIL-R4-B (TRAIL-R4) mRNA, complete cds. /FEA=mRNA /GEN=TRAIL-R4 /PROD=TRAIL-R4-B /DB_XREF=gi:3452184 /UG=Hs.129844 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain /FL=gb:AF023849.1 gb:AF021232.1 gb:AF021233.1 gb:AF029761.1 gb:NM_003840.1 AF021233 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain TNFRSF10D 8793 NM_003840 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045569 // TRAIL binding // inferred from electronic annotation 210655_s_at AF041336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF041336.1 /DEF=Homo sapiens fork head-like protein (FKHRL1P2) mRNA, complete cds. /FEA=mRNA /GEN=FKHRL1P2 /PROD=fork head-like protein /DB_XREF=gi:4106722 /UG=Hs.14845 forkhead box O3A /FL=gb:AF041336.1 AF041336 forkhead box O3 /// forkhead box O3B pseudogene FOXO3 /// FOXO3B 2309 /// 2310 NM_001455 /// NM_201559 /// NR_026718 /// XM_005266867 /// XM_005266868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay 210656_at AF099032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF099032.1 /DEF=Homo sapiens embryonic ectoderm development protein short isoform mRNA, complete cds. /FEA=mRNA /PROD=embryonic ectoderm development protein shortisoform /DB_XREF=gi:3851653 /UG=Hs.151461 embryonic ectoderm development /FL=gb:AF099032.1 AF099032 embryonic ectoderm development EED 8726 NM_003797 /// NM_152991 /// XM_005274373 /// XM_006718730 /// XM_006718731 /// XR_247215 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from electronic annotation 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 210657_s_at U88870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88870.1 /DEF=Human cell division control-related protein 2b (hcdcrel2b) mRNA, complete cds. /FEA=mRNA /GEN=hcdcrel2b /PROD=cell division control-related protein 2b /DB_XREF=gi:4099608 /UG=Hs.155524 peanut (Drosophila)-like 2 /FL=gb:U88870.1 U88870 septin 4 SEPT4 5414 NM_001198713 /// NM_001256782 /// NM_001256822 /// NM_004574 /// NM_080415 /// NM_080416 /// NM_080417 /// NR_037155 /// NR_104196 /// NR_104197 /// XM_006721949 /// XM_006721950 /// XM_006721951 /// XM_006721952 /// XM_006721953 /// XM_006721954 /// XM_006721955 0000910 // cytokinesis // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0030382 // sperm mitochondrion organization // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048240 // sperm capacitation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 210658_s_at BC000284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000284.1 /DEF=Homo sapiens, KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2, clone MGC:1002, mRNA, complete cds. /FEA=mRNA /PROD=KIAA1080 protein; Golgi-associated,gamma-adaptin ear containing, ARF-binding protein 2 /DB_XREF=gi:12653040 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 /FL=gb:BC000284.1 BC000284 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 210659_at U79526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79526.1 /DEF=Human orphan G-protein coupled receptor Dez isoform a mRNA, complete cds. /FEA=mRNA /PROD=orphan G-protein coupled receptor Dez isoform a /DB_XREF=gi:1732342 /UG=Hs.159553 chemokine-like receptor 1 /FL=gb:U79526.1 U79526 chemokine-like receptor 1 CMKLR1 1240 NM_001142343 /// NM_001142344 /// NM_001142345 /// NM_004072 0001501 // skeletal system development // traceable author statement /// 0006935 // chemotaxis // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0010759 // positive regulation of macrophage chemotaxis // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050848 // regulation of calcium-mediated signaling // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210660_at AF025529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF025529.1 /DEF=Homo sapiens leucocyte immunoglobulin-like receptor-6b (LIR-6) mRNA, complete cds. /FEA=mRNA /GEN=LIR-6 /PROD=leucocyte immunoglobulin-like receptor-6b /DB_XREF=gi:2653864 /UG=Hs.166156 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 /FL=gb:AF025529.1 AF025529 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 LILRA1 11024 NM_001278318 /// NM_001278319 /// NM_006863 /// NR_103501 /// NR_103502 /// NR_103503 /// XM_006722979 /// XM_006722980 /// XM_006722981 /// XM_006722982 /// XM_006726171 /// XM_006726172 /// XM_006726173 /// XM_006726174 /// XM_006726258 /// XM_006726259 /// XM_006726260 /// XM_006726261 /// XM_006726294 /// XM_006726295 /// XM_006726296 /// XM_006726297 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210661_at U93917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U93917.1 /DEF=Human glycine receptor alpha 3 subunit mRNA, complete cds. /FEA=mRNA /PROD=glycine receptor alpha 3 subunit /DB_XREF=gi:3342235 /UG=Hs.167742 glycine receptor, alpha 3 /FL=gb:U93917.1 U93917 glycine receptor, alpha 3 GLRA3 8001 NM_001042543 /// NM_006529 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016935 // glycine-gated chloride channel complex // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // non-traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from electronic annotation /// 0022824 // transmitter-gated ion channel activity // inferred from electronic annotation /// 0030594 // neurotransmitter receptor activity // non-traceable author statement 210662_at BC000879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000879.1 /DEF=Homo sapiens, Similar to kynureninase (L-kynurenine hydrolase), clone MGC:5080, mRNA, complete cds. /FEA=mRNA /PROD=Similar to kynureninase (L-kynureninehydrolase) /DB_XREF=gi:12654128 /UG=Hs.169139 kynureninase (L-kynurenine hydrolase) /FL=gb:BC000879.1 BC000879 kynureninase KYNU 8942 NM_001032998 /// NM_001199241 /// NM_003937 0006569 // tryptophan catabolic process // inferred from mutant phenotype /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034516 // response to vitamin B6 // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030429 // kynureninase activity // inferred from direct assay /// 0030429 // kynureninase activity // inferred from mutant phenotype /// 0030429 // kynureninase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 210663_s_at BC000879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000879.1 /DEF=Homo sapiens, Similar to kynureninase (L-kynurenine hydrolase), clone MGC:5080, mRNA, complete cds. /FEA=mRNA /PROD=Similar to kynureninase (L-kynureninehydrolase) /DB_XREF=gi:12654128 /UG=Hs.169139 kynureninase (L-kynurenine hydrolase) /FL=gb:BC000879.1 BC000879 kynureninase KYNU 8942 NM_001032998 /// NM_001199241 /// NM_003937 0006569 // tryptophan catabolic process // inferred from mutant phenotype /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034516 // response to vitamin B6 // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030429 // kynureninase activity // inferred from direct assay /// 0030429 // kynureninase activity // inferred from mutant phenotype /// 0030429 // kynureninase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 210664_s_at AF021834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF021834.1 /DEF=Homo sapiens tissue factor pathway inhibitor beta (TFPIbeta) mRNA, complete cds. /FEA=mRNA /GEN=TFPIbeta /PROD=tissue factor pathway inhibitor beta /DB_XREF=gi:4103170 /UG=Hs.170279 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) /FL=gb:AF021834.1 AF021834 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 7035 NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210665_at AF021834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF021834.1 /DEF=Homo sapiens tissue factor pathway inhibitor beta (TFPIbeta) mRNA, complete cds. /FEA=mRNA /GEN=TFPIbeta /PROD=tissue factor pathway inhibitor beta /DB_XREF=gi:4103170 /UG=Hs.170279 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) /FL=gb:AF021834.1 AF021834 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 7035 NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210666_at AF050145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF050145.1 /DEF=Homo sapiens iduronate-2-sulfatase (IDS) mRNA, complete cds. /FEA=mRNA /GEN=IDS /PROD=iduronate-2-sulfatase /DB_XREF=gi:2970558 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:AF050145.1 AF050145 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210667_s_at D86062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86062.1 /DEF=Human mRNA for KNP-Ib, complete cds. /FEA=mRNA /GEN=KNP-I /PROD=KNP-Ib /DB_XREF=gi:1545814 /UG=Hs.182423 ES1 (zebrafish) protein, human homolog of /FL=gb:D86062.1 D86062 chromosome 21 open reading frame 33 C21orf33 8209 NM_004649 /// NM_198155 /// XM_005261184 /// XM_005261185 /// XM_005261186 /// XM_006724055 /// XM_006724056 0005739 // mitochondrion // not recorded 210669_at M61156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M61156.1 /DEF=Human activator protein 2B (AP-2B) mRNA, complete cds. /FEA=mRNA /GEN=AP-2B /PROD=activator protein 2B /DB_XREF=gi:178704 /UG=Hs.18387 transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) /FL=gb:M61156.1 M61156 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) TFAP2A 7020 NM_001032280 /// NM_001042425 /// NM_003220 /// XM_006715175 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001822 // kidney development // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0003404 // optic vesicle morphogenesis // inferred from sequence or structural similarity /// 0003409 // optic cup structural organization // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007423 // sensory organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010842 // retina layer formation // inferred from expression pattern /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0021506 // anterior neuropore closure // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021623 // oculomotor nerve formation // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from electronic annotation /// 0070172 // positive regulation of tooth mineralization // inferred from direct assay /// 0071281 // cellular response to iron ion // inferred from direct assay /// 0071711 // basement membrane organization // inferred from electronic annotation /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 210670_at M15788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15788.1 /DEF=Human pancreatic polypeptide Y mRNA, complete cds. /FEA=mRNA /GEN=PPY /DB_XREF=gi:190301 /UG=Hs.184604 pancreatic polypeptide /FL=gb:M15788.1 gb:NM_002722.1 M15788 pancreatic polypeptide PPY 5539 NM_002722 0007586 // digestion // traceable author statement /// 0009306 // protein secretion // traceable author statement 0005576 // extracellular region // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 210671_x_at U35004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35004.1 /DEF=Human JNK1 beta1 protein kinase (JNK1B1) mRNA, complete cds. /FEA=mRNA /GEN=JNK1B1 /PROD=JNK1 beta1 protein kinase /DB_XREF=gi:1463136 /UG=Hs.190913 mitogen-activated protein kinase 8 /FL=gb:U35004.1 gb:U35005.1 U35004 mitogen-activated protein kinase 8 MAPK8 5599 NM_001278547 /// NM_001278548 /// NM_002750 /// NM_139046 /// NM_139049 /// XM_006717917 /// XM_006717918 /// XM_006717919 0000165 // MAPK cascade // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from direct assay /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0031063 // regulation of histone deacetylation // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090045 // positive regulation of deacetylase activity // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000017 // positive regulation of determination of dorsal identity // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004705 // JUN kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035033 // histone deacetylase regulator activity // inferred from mutant phenotype /// 0042826 // histone deacetylase binding // inferred from physical interaction 210672_s_at BC004185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004185.1 /DEF=Homo sapiens, Similar to Conserved gene telomeric to alpha globin cluster, clone MGC:2816, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Conserved gene telomeric to alphaglobin cluster /DB_XREF=gi:13278839 /UG=Hs.19699 Conserved gene telomeric to alpha globin cluster /FL=gb:BC004185.1 BC004185 nitrogen permease regulator-like 3 (S. cerevisiae) NPRL3 8131 NM_001039476 /// NM_001077350 /// NM_001243247 /// NM_001243248 /// NM_001243249 /// NM_012075 0003281 // ventricular septum development // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation 210673_x_at D50740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50740.1 /DEF=Homo sapiens mRNA for thyroid transcriptional factor-1, complete cds. /FEA=mRNA /PROD=thyroid transcriptional factor-1 /DB_XREF=gi:2627170 /UG=Hs.197764 thyroid transcription factor 1 /FL=gb:D50740.1 D50740 NK2 homeobox 1 NKX2-1 7080 NM_001079668 /// NM_003317 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007492 // endoderm development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009725 // response to hormone // inferred from expression pattern /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021759 // globus pallidus development // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021798 // forebrain dorsal/ventral pattern formation // inferred from electronic annotation /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030324 // lung development // inferred from expression pattern /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from expression pattern /// 0031128 // developmental induction // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0042696 // menarche // inferred from electronic annotation /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from expression pattern /// 0060486 // Clara cell differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 210674_s_at AF152308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152308.1 /DEF=Homo sapiens protocadherin alpha 12 (PCDH-alpha12) mRNA, complete cds. /FEA=mRNA /GEN=PCDH-alpha12 /PROD=protocadherin alpha 12 /DB_XREF=gi:5456901 /UG=Hs.197873 protocadherin alpha 12 /FL=gb:AF152308.1 gb:AF152477.1 gb:NM_018903.1 AF152308 protocadherin alpha 1 /// protocadherin alpha 10 /// protocadherin alpha 11 /// protocadherin alpha 12 /// protocadherin alpha 13 /// protocadherin alpha 2 /// protocadherin alpha 3 /// protocadherin alpha 4 /// protocadherin alpha 5 /// protocadherin alpha 6 /// protocadherin alpha 7 /// protocadherin alpha 8 /// protocadherin alpha 9 /// protocadherin alpha subfamily C, 1 /// protocadherin alpha subfamily C, 2 PCDHA1 /// PCDHA10 /// PCDHA11 /// PCDHA12 /// PCDHA13 /// PCDHA2 /// PCDHA3 /// PCDHA4 /// PCDHA5 /// PCDHA6 /// PCDHA7 /// PCDHA8 /// PCDHA9 /// PCDHAC1 /// PCDHAC2 9752 /// 56134 /// 56135 /// 56136 /// 56137 /// 56138 /// 56139 /// 56140 /// 56141 /// 56142 /// 56143 /// 56144 /// 56145 /// 56146 /// 56147 NM_014005 /// NM_018898 /// NM_018899 /// NM_018900 /// NM_018901 /// NM_018902 /// NM_018903 /// NM_018904 /// NM_018905 /// NM_018906 /// NM_018907 /// NM_018908 /// NM_018909 /// NM_018910 /// NM_018911 /// NM_031410 /// NM_031411 /// NM_031495 /// NM_031496 /// NM_031497 /// NM_031500 /// NM_031501 /// NM_031848 /// NM_031849 /// NM_031852 /// NM_031856 /// NM_031857 /// NM_031859 /// NM_031860 /// NM_031861 /// NM_031864 /// NM_031865 /// NM_031882 /// NM_031883 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 210675_s_at U77917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U77917.1 /DEF=Human Ch-1PTPase gamma minus form mRNA, complete cds. /FEA=mRNA /PROD=Ch-1PTPase gamma minus form /DB_XREF=gi:2078324 /UG=Hs.198288 protein tyrosine phosphatase, receptor type, R /FL=gb:U77917.1 U77917 protein tyrosine phosphatase, receptor type, R PTPRR 5801 NM_001207015 /// NM_001207016 /// NM_002849 /// NM_130846 /// NR_073474 0001701 // in utero embryonic development // inferred from expression pattern /// 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 210676_x_at U64675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U64675.2 /DEF=Homo sapiens sperm membrane protein BS-63 mRNA, complete cds. /FEA=mRNA /PROD=sperm membrane protein BS-63 /DB_XREF=gi:5809677 /UG=Hs.199179 RAN binding protein 2 /FL=gb:U64675.2 U64675 RANBP2-like and GRIP domain containing 3 /// RANBP2-like and GRIP domain containing 4 /// RANBP2-like and GRIP domain containing 5 /// RANBP2-like and GRIP domain containing 6 /// RANBP2-like and GRIP domain containing 8 RGPD3 /// RGPD4 /// RGPD5 /// RGPD6 /// RGPD8 84220 /// 285190 /// 653489 /// 727851 /// 729540 NM_001037866 /// NM_001123363 /// NM_001144013 /// NM_001164463 /// NM_005054 /// NM_032260 /// NM_182588 /// XM_005263747 /// XM_005263748 /// XM_005263753 /// XM_005263755 /// XM_005263756 /// XM_005263819 /// XM_005263820 /// XM_005263821 /// XM_005263822 /// XM_006712454 /// XM_006712708 /// XM_006712794 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // non-traceable author statement 210677_at AF059203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF059203.1 /DEF=Homo sapiens acyl coenzyme A:cholesterol acyltransferase 2 mRNA, complete cds. /FEA=mRNA /PROD=acyl coenzyme A:cholesterol acyltransferase 2 /DB_XREF=gi:3746534 /UG=Hs.20580 sterol O-acyltransferase 2 /FL=gb:AF059203.1 gb:NM_003578.1 gb:AF099031.2 AF059203 sterol O-acyltransferase 2 SOAT2 8435 NM_003578 /// XR_245960 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010742 // macrophage derived foam cell differentiation // traceable author statement /// 0030299 // intestinal cholesterol absorption // inferred by curator /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034435 // cholesterol esterification // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005903 // brush border // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0004772 // sterol O-acyltransferase activity // inferred from electronic annotation /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0034736 // cholesterol O-acyltransferase activity // inferred from direct assay 210678_s_at U56418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U56418.1 /DEF=Human lysophosphatidic acid acyltransferase-beta mRNA, complete cds. /FEA=mRNA /PROD=lysophosphatidic acid acyltransferase-beta /DB_XREF=gi:2155239 /UG=Hs.209119 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) /FL=gb:U56418.1 U56418 1-acylglycerol-3-phosphate O-acyltransferase 2 AGPAT2 10555 NM_001012727 /// NM_006412 0001819 // positive regulation of cytokine production // inferred from mutant phenotype /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred by curator /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // inferred from genetic interaction /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from genetic interaction /// 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 210679_x_at BC002629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002629.1 /DEF=Homo sapiens, clone MGC:3878, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3878) /DB_XREF=gi:12803588 /UG=Hs.211563 B-cell CLLlymphoma 7A /FL=gb:BC002629.1 BC002629 210680_s_at D17525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D17525.1 /DEF=Human mRNA for precursor of P100 serine protease of Ra-reactive factor, complete cds. /FEA=mRNA /GEN=CRARF /PROD=precursor of P100 serine protease of Ra-reactivefactor /DB_XREF=gi:439712 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) /FL=gb:D17525.1 D17525 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) MASP1 5648 NM_001031849 /// NM_001879 /// NM_139125 /// NR_033519 /// XM_006713700 /// XM_006713701 0001867 // complement activation, lectin pathway // inferred from mutant phenotype /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210681_s_at AF153604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153604.1 /DEF=Homo sapiens ubiquitin-specific protease homolog (UPH) mRNA, complete cds. /FEA=mRNA /GEN=UPH /PROD=ubiquitin-specific protease homolog /DB_XREF=gi:5231132 /UG=Hs.23168 ubiquitin specific protease 15 /FL=gb:AF153604.1 AF153604 microRNA 6125 /// ubiquitin specific peptidase 15 MIR6125 /// USP15 9958 /// 102465133 NM_001252078 /// NM_001252079 /// NM_006313 /// NR_106740 /// XM_005269259 /// XM_005269261 /// XM_006719718 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0035520 // monoubiquitinated protein deubiquitination // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction 210682_at U39573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U39573.1 /DEF=Human salivary peroxidase mRNA, complete cds. /FEA=mRNA /PROD=salivary peroxidase /DB_XREF=gi:1209684 /UG=Hs.234742 lactoperoxidase /FL=gb:U39573.1 U39573 lactoperoxidase LPO 4025 NM_001160102 /// NM_006151 /// NR_027647 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0006979 // response to oxidative stress // non-traceable author statement /// 0018969 // thiocyanate metabolic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0036393 // thiocyanate peroxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210683_at AL161995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL161995.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762B0211 (from clone DKFZp762B0211); complete cds. /FEA=mRNA /GEN=DKFZp762B0211 /PROD=hypothetical protein /DB_XREF=gi:7328129 /UG=Hs.234775 neurturin /FL=gb:U78110.1 gb:NM_004558.1 gb:AL161995.1 AL161995 neurturin NRTN 4902 NM_004558 0000165 // MAPK cascade // traceable author statement /// 0001755 // neural crest cell migration // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0021675 // nerve development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 210684_s_at AF028825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF028825.1 /DEF=Homo sapiens Tax interaction protein 15 mRNA, complete cds. /FEA=mRNA /PROD=Tax interaction protein 15 /DB_XREF=gi:2613005 /UG=Hs.23731 discs, large (Drosophila) homolog 4 /FL=gb:AF028825.1 AF028825 discs, large homolog 4 (Drosophila) DLG4 1742 NM_001128827 /// NM_001365 /// XM_005256489 /// XM_005256491 /// XM_005256492 /// XM_005256493 /// XM_005256494 /// XR_243545 0001973 // adenosine receptor signaling pathway // inferred from sequence or structural similarity /// 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007612 // learning // traceable author statement /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from direct assay /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0050806 // positive regulation of synaptic transmission // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from electronic annotation /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from sequence or structural similarity /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // traceable author statement /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0032839 // dendrite cytoplasm // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0044309 // neuron spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031697 // beta-1 adrenergic receptor binding // inferred from sequence or structural similarity /// 0031748 // D1 dopamine receptor binding // inferred from sequence or structural similarity /// 0031812 // P2Y1 nucleotide receptor binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0033130 // acetylcholine receptor binding // inferred from sequence or structural similarity /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity /// 0045031 // ATP-activated nucleotide receptor activity // inferred from sequence or structural similarity /// 0045032 // ADP-activated nucleotide receptor activity // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 210685_s_at AB028839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB028839.1 /DEF=Homo sapiens HDNB1(homzygously deleted in neuroblastoma-1)UFD2 mRNA, complete cds. /FEA=mRNA /GEN=HDNB1UFD2 /PROD=homzygously deleted in neuroblastoma-1UFD2 /DB_XREF=gi:13516466 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) /FL=gb:AB028839.1 AB028839 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 210686_x_at BC001407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001407.1 /DEF=Homo sapiens, Similar to cytochrome c-like antigen, clone MGC:2960, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cytochrome c-like antigen /DB_XREF=gi:12655110 /UG=Hs.253070 Homo sapiens, Similar to cytochrome c-like antigen, clone MGC:2960, mRNA, complete cds /FL=gb:BC001407.1 BC001407 solute carrier family 25 (mitochondrial carrier), member 16 SLC25A16 8034 NM_152707 /// XM_005270183 /// XM_006717987 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // non-traceable author statement /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // non-traceable author statement 210687_at BC000185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000185.1 /DEF=Homo sapiens, Similar to carnitine palmitoyltransferase I, liver, clone MGC:1772, mRNA, complete cds. /FEA=mRNA /PROD=Similar to carnitine palmitoyltransferase I,liver /DB_XREF=gi:12652864 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:BC000185.1 BC000185 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 210688_s_at BC000185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000185.1 /DEF=Homo sapiens, Similar to carnitine palmitoyltransferase I, liver, clone MGC:1772, mRNA, complete cds. /FEA=mRNA /PROD=Similar to carnitine palmitoyltransferase I,liver /DB_XREF=gi:12652864 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:BC000185.1 BC000185 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 210689_at AF314090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF314090.1 /DEF=Homo sapiens claudin 14 (CLDN14) mRNA, complete cds. /FEA=mRNA /GEN=CLDN14 /PROD=claudin 14 /DB_XREF=gi:12597446 /UG=Hs.266416 claudin 14 /FL=gb:AF314090.1 gb:NM_012130.1 AF314090 claudin 14 CLDN14 23562 NM_001146077 /// NM_001146078 /// NM_001146079 /// NM_012130 /// NM_144492 0006461 // protein complex assembly // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 210690_at U96845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96845.1 /DEF=Homo sapiens natual killer cell group 2-F (NKG2-F) mRNA, complete cds. /FEA=mRNA /GEN=NKG2-F /PROD=natual killer cell group 2-F /DB_XREF=gi:2673988 /UG=Hs.268510 killer cell lectin-like receptor subfamily C, member 4 /FL=gb:U96845.1 gb:NM_013431.1 U96845 killer cell lectin-like receptor subfamily C, member 4 KLRC4 8302 NM_013431 0006968 // cellular defense response // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210691_s_at AF275803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF275803.1 /DEF=Homo sapiens PNAS-107 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-107 /DB_XREF=gi:10834769 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF275803.1 AF275803 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 210692_s_at BC003163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003163.1 /DEF=Homo sapiens, Similar to selectively expressed in embryonic epithelia protein-1, clone MGC:4220, mRNA, complete cds. /FEA=mRNA /PROD=Similar to selectively expressed in embryonicepithelia protein-1 /DB_XREF=gi:13111980 /UG=Hs.274453 hypothetical protein DKFZp762A227 /FL=gb:BC003163.1 BC003163 solute carrier family 43, member 3 SLC43A3 29015 NM_001278201 /// NM_001278206 /// NM_014096 /// NM_017611 /// NM_199329 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210693_at BC001788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001788.1 /DEF=Homo sapiens, Similar to hypothetical protein from EUROIMAGE 42353, clone MGC:2606, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein from EUROIMAGE42353 /DB_XREF=gi:12804714 /UG=Hs.274737 Homo sapiens, Similar to hypothetical protein from EUROIMAGE 42353, clone MGC:2606, mRNA, complete cds /FL=gb:BC001788.1 BC001788 signal peptide peptidase like 2B SPPL2B 56928 NM_001077238 /// NM_152988 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // inferred from mutant phenotype /// 0050776 // regulation of immune response // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0071458 // integral component of cytoplasmic side of endoplasmic reticulum membrane // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042500 // aspartic endopeptidase activity, intramembrane cleaving // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay 210694_s_at AF041209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF041209.1 /DEF=Homo sapiens midline 1 fetal kidney isoform 2 (MID1) mRNA, complete cds. /FEA=mRNA /GEN=MID1 /PROD=midline 1 fetal kidney isoform 2 /DB_XREF=gi:3462508 /UG=Hs.27695 midline 1 (OpitzBBB syndrome) /FL=gb:AF041209.1 AF041209 midline 1 MID1 4281 NM_000381 /// NM_001098624 /// NM_001193277 /// NM_001193278 /// NM_001193279 /// NM_001193280 /// NM_001193281 /// NM_033289 /// NM_033290 /// NM_033291 /// XM_005274536 /// XM_005274537 /// XM_005274538 /// XM_006724492 /// XM_006724493 /// XR_247298 /// XR_247299 /// XR_247300 /// XR_250630 /// XR_250631 /// XR_250632 /// XR_254127 /// XR_254128 /// XR_254129 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 210695_s_at U13395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13395.1 /DEF=Human oxidoreductase (HHCMA56) mRNA, complete cds. /FEA=mRNA /GEN=HHCMA56 /PROD=oxidoreductase /DB_XREF=gi:538131 /UG=Hs.279790 putative oxidoreductase /FL=gb:U13395.1 U13395 WW domain containing oxidoreductase WWOX 51741 NM_001291997 /// NM_016373 /// NM_018560 /// NM_130788 /// NM_130790 /// NM_130791 /// NM_130792 /// NM_130844 /// NR_120435 /// NR_120436 /// XM_006721195 /// XR_243411 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0046983 // protein dimerization activity // traceable author statement /// 0048037 // cofactor binding // traceable author statement /// 0050662 // coenzyme binding // traceable author statement 210697_at AF070651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070651.1 /DEF=Homo sapiens tissue-type bone marrow zinc finger protein 4 mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 4 /DB_XREF=gi:4454677 /UG=Hs.283900 Homo sapiens tissue-type bone marrow zinc finger protein 4 mRNA, complete cds /FL=gb:AF070651.1 AF070651 zinc finger protein 257 ZNF257 113835 NM_033468 /// XM_005259723 /// XM_005259724 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210698_at AF090895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF090895.1 /DEF=Homo sapiens clone HQ0117 PRO0117 mRNA, complete cds. /FEA=mRNA /PROD=PRO0117 /DB_XREF=gi:6690166 /UG=Hs.283919 Homo sapiens clone HQ0117 PRO0117 mRNA, complete cds /FL=gb:AF090895.1 AF090895 210699_at AF116679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116679.1 /DEF=Homo sapiens PRO2003 mRNA, complete cds. /FEA=mRNA /PROD=PRO2003 /DB_XREF=gi:7959856 /UG=Hs.288036 tRNA isopentenylpyrophosphate transferase /FL=gb:AF116679.1 AF116679 210701_at D85939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D85939.1 /DEF=Homo sapiens mRNA for p97 homologous protein, complete cds. /FEA=mRNA /PROD=p97 homologous protein /DB_XREF=gi:2114175 /UG=Hs.296460 craniofacial development protein 1 /FL=gb:D85939.1 D85939 craniofacial development protein 1 CFDP1 10428 NM_006324 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 210702_s_at D38145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38145.1 /DEF=Human mRNA for prostacyclin synthase, complete cds. /FEA=mRNA /GEN=PTGIS /PROD=prostacyclin synthase /DB_XREF=gi:537948 /UG=Hs.302085 prostaglandin I2 (prostacyclin) synthase /FL=gb:D38145.1 D38145 prostaglandin I2 (prostacyclin) synthase PTGIS 5740 NM_000961 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008116 // prostaglandin-I synthase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210703_at AF132204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF132204.1 /DEF=Homo sapiens PRO2259 mRNA, complete cds. /FEA=mRNA /PROD=PRO2259 /DB_XREF=gi:11493553 /UG=Hs.302159 Homo sapiens PRO2259 mRNA, complete cds /FL=gb:AF132204.1 AF132204 210704_at L17328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L17328.1 /DEF=Human pre-TNK cell associated protein (3Cl) mRNA, complete cds. /FEA=mRNA /GEN=3Cl /DB_XREF=gi:306331 /UG=Hs.302176 Homo sapiens fasciculation and elongation protein zeta 2 (zygin II) (FEZ2), mRNA /FL=gb:L17328.1 L17328 fasciculation and elongation protein zeta 2 (zygin II) FEZ2 9637 NM_001042548 /// NM_005102 /// XM_006712153 /// XR_244972 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005515 // protein binding // inferred from physical interaction 210705_s_at AF220028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220028.1 /DEF=Homo sapiens tripartite motif protein TRIM5 isoform delta (TRIM5) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM5 /PROD=tripartite motif protein TRIM5 isoform delta /DB_XREF=gi:12407386 /UG=Hs.30445 Homo sapiens tripartite motif protein TRIM5 isoform epsilon (TRIM5) mRNA, complete cds; alternatively spliced /FL=gb:AF220028.1 AF220028 tripartite motif containing 5 TRIM5 85363 NM_033034 /// NM_033092 /// NM_033093 /// XM_005253183 /// XM_005253184 /// XM_006718358 0002218 // activation of innate immune response // inferred from direct assay /// 0002221 // pattern recognition receptor signaling pathway // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // traceable author statement /// 0070206 // protein trimerization // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008329 // signaling pattern recognition receptor activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210706_s_at BC000213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000213.1 /DEF=Homo sapiens, ring finger protein 24, clone MGC:1815, mRNA, complete cds. /FEA=mRNA /PROD=ring finger protein 24 /DB_XREF=gi:12802985 /UG=Hs.30524 ring finger protein 24 /FL=gb:BC000213.1 BC000213 ring finger protein 24 RNF24 11237 NM_001134337 /// NM_001134338 /// NM_007219 /// XM_006723536 /// XM_006723537 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210707_x_at U38980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38980.1 /DEF=Human PMS2 related (hPMSR6) mRNA, complete cds. /FEA=mRNA /GEN=hPMSR6 /PROD=hPMSR6 /DB_XREF=gi:1061425 /UG=Hs.306174 postmeiotic segregation increased 2-like 11 /FL=gb:U38980.1 U38980 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene DTX2P1-UPK3BP1-PMS2P11 441263 NR_023383 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 210708_x_at AF111344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF111344.1 /DEF=Homo sapiens caspase-10c mRNA, complete cds. /FEA=mRNA /PROD=caspase-10c /DB_XREF=gi:4731236 /UG=Hs.306531 Homo sapiens caspase-10c mRNA, complete cds /FL=gb:AF111344.1 AF111344 caspase 10, apoptosis-related cysteine peptidase CASP10 843 NM_001206524 /// NM_001206542 /// NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 /// XM_005246907 /// XM_005246909 /// XM_005246910 /// XM_005246911 /// XM_006712796 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0045087 // innate immune response // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0097342 // ripoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 210709_at AF119892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119892.1 /DEF=Homo sapiens PRO2710 mRNA, complete cds. /FEA=mRNA /PROD=PRO2710 /DB_XREF=gi:7770220 /UG=Hs.306572 Homo sapiens PRO2710 mRNA, complete cds /FL=gb:AF119892.1 AF119892 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210710_at BC002828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002828.1 /DEF=Homo sapiens, Similar to fetal hypothetical protein, clone MGC:3843, mRNA, complete cds. /FEA=mRNA /PROD=Similar to fetal hypothetical protein /DB_XREF=gi:12803960 /UG=Hs.306986 Homo sapiens, Similar to fetal hypothetical protein, clone MGC:3843, mRNA, complete cds /FL=gb:BC002828.1 BC002828 angiogenic factor with G patch and FHA domains 1 AGGF1 55109 NM_018046 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210711_at BC000988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000988.2 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20489, clone MGC:5457, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20489 /DB_XREF=gi:12803032 /UG=Hs.306995 Homo sapiens, Similar to hypothetical protein FLJ20489, clone MGC:5457, mRNA, complete cds /FL=gb:BC000988.2 BC000988 long intergenic non-protein coding RNA 260 LINC00260 84719 NM_032633 /// NR_046213 210712_at AY009108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY009108.1 /DEF=Homo sapiens lactate dehydrogenase A mRNA, complete cds. /FEA=mRNA /PROD=lactate dehydrogenase A /DB_XREF=gi:12330999 /UG=Hs.307052 Homo sapiens lactate dehydrogenase A mRNA, complete cds /FL=gb:AY009108.1 AY009108 lactate dehydrogenase A-like 6B LDHAL6B 92483 NM_033195 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 210713_at U61166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U61166.1 /DEF=Human SH3 domain-containing protein SH3P17 mRNA, complete cds. /FEA=mRNA /PROD=SH3 domain-containing protein SH3P17 /DB_XREF=gi:1438932 /UG=Hs.307177 Human SH3 domain-containing protein SH3P17 mRNA, complete cds /FL=gb:U61166.1 U61166 intersectin 1 (SH3 domain protein) ITSN1 6453 NM_001001132 /// NM_003024 /// XM_005261026 /// XM_005261027 /// XM_005261031 /// XR_244289 0006897 // endocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 210714_at BC001217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001217.1 /DEF=Homo sapiens, Similar to KIAA0029 protein, clone MGC:767, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0029 protein /DB_XREF=gi:12654748 /UG=Hs.312480 Homo sapiens, Similar to KIAA0029 protein, clone MGC:767, mRNA, complete cds /FL=gb:BC001217.1 BC001217 R3H domain containing 1 R3HDM1 23518 NM_001282798 /// NM_001282799 /// NM_001282800 /// NM_015361 /// XM_005263622 /// XM_005263623 /// XM_005263624 /// XM_005263626 /// XM_005263627 /// XM_005263628 /// XM_005263629 /// XM_005263631 /// XM_005263632 /// XM_005263633 /// XM_006712389 /// XM_006712390 /// XM_006712391 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210715_s_at AF027205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF027205.1 /DEF=Homo sapiens Kunitz-type protease inhibitor (kop) mRNA, complete cds. /FEA=mRNA /GEN=kop /PROD=Kunitz-type protease inhibitor /DB_XREF=gi:2598967 /UG=Hs.31439 serine protease inhibitor, Kunitz type, 2 /FL=gb:AF027205.1 AF027205 serine peptidase inhibitor, Kunitz type, 2 SPINT2 10653 NM_001166103 /// NM_021102 0006928 // cellular component movement // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210716_s_at M97501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M97501.1 /DEF=Human cytoplasmic linker protein-170 alpha-2 (CLIP-170) mRNA, complete cds. /FEA=mRNA /PROD=cytoplasmic linker protein-170 alpha-2 /DB_XREF=gi:180621 /UG=Hs.31638 restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) /FL=gb:M97501.1 M97501 CAP-GLY domain containing linker protein 1 CLIP1 6249 NM_001247997 /// NM_002956 /// NM_198240 /// XM_005253593 /// XM_005253594 /// XM_005253595 /// XM_006719551 /// XM_006719552 /// XM_006719553 /// XM_006719554 /// XM_006719555 0000278 // mitotic cell cycle // traceable author statement /// 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from mutant phenotype 0000776 // kinetochore // traceable author statement /// 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from mutant phenotype /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0044354 // macropinosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // non-traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 210717_at AF116659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116659.1 /DEF=Homo sapiens PRO1412 mRNA, complete cds. /FEA=mRNA /PROD=PRO1412 /DB_XREF=gi:7959816 /UG=Hs.321151 Homo sapiens PRO1412 mRNA, complete cds /FL=gb:AF116659.1 AF116659 210718_s_at AF119889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119889.1 /DEF=Homo sapiens PRO2667 mRNA, complete cds. /FEA=mRNA /PROD=PRO2667 /DB_XREF=gi:7770214 /UG=Hs.321170 Homo sapiens PRO2667 mRNA, complete cds /FL=gb:AF119889.1 AF119889 ADP-ribosylation factor-like 17A /// ADP-ribosylation factor-like 17B /// ADP-ribosylation factor-like protein 17-like ARL17A /// ARL17B /// LOC100294341 51326 /// 100294341 /// 100506084 NM_001039083 /// NM_001103154 /// NM_001113738 /// NM_001288811 /// NM_001288812 /// NM_001288813 /// NM_016632 /// NR_003653 /// XM_005256917 /// XM_005256918 /// XM_005257439 /// XM_005257440 /// XM_005257441 /// XM_005275670 /// XM_005275671 /// XM_005275672 /// XM_005275673 /// XM_006725627 /// XM_006725628 /// XM_006725629 /// XM_006725630 /// XR_429866 /// XR_429895 /// XR_430776 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 210719_s_at BC002552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002552.1 /DEF=Homo sapiens, high-mobility group 20B, clone MGC:1965, mRNA, complete cds. /FEA=mRNA /PROD=high-mobility group 20B /DB_XREF=gi:12803454 /UG=Hs.32317 high-mobility group 20B /FL=gb:BC002552.1 BC002552 high mobility group 20B HMG20B 10362 NM_006339 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033234 // negative regulation of protein sumoylation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210720_s_at AB039947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB039947.1 /DEF=Homo sapiens XB51 mRNA for X11L-binding protein 51, complete cds. /FEA=mRNA /GEN=XB51 /PROD=X11L-binding protein 51 /DB_XREF=gi:10798740 /UG=Hs.324104 X11L-binding protein 51 /FL=gb:AB039947.1 AB039947 N-terminal EF-hand calcium binding protein 3 NECAB3 63941 NM_031231 /// NM_031232 /// XM_005260510 /// XR_244145 0009306 // protein secretion // non-traceable author statement /// 0019538 // protein metabolic process // inferred from direct assay /// 0042984 // regulation of amyloid precursor protein biosynthetic process // inferred from direct assay 0000137 // Golgi cis cisterna // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210721_s_at AB040812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB040812.1 /DEF=Homo sapiens mRNA for protein kinase PAK5, complete cds. /FEA=mRNA /GEN=PAK5 /PROD=protein kinase PAK5 /DB_XREF=gi:7649809 /UG=Hs.32539 KIAA1264 protein /FL=gb:AB040812.1 AB040812 p21 protein (Cdc42/Rac)-activated kinase 7 PAK7 57144 NM_020341 /// NM_177990 /// XM_005260766 /// XM_006723597 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210722_at BC005233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005233.1 /DEF=Homo sapiens, clone MGC:12257, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12257) /DB_XREF=gi:13528866 /UG=Hs.326711 Homo sapiens, clone MGC:12257, mRNA, complete cds /FL=gb:BC005233.1 BC005233 pancreatic lipase-related protein 1 PNLIPRP1 5407 NM_006229 /// XM_005269903 0006629 // lipid metabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0016298 // lipase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210723_x_at BC004917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004917.1 /DEF=Homo sapiens, clone MGC:4771, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4771) /DB_XREF=gi:13436223 /UG=Hs.326743 Homo sapiens, clone MGC:4771, mRNA, complete cds /FL=gb:BC004917.1 BC004917 Homo sapiens hypothetical protein MGC4771, mRNA (cDNA clone IMAGE:3542169), partial cds. BC069004 210724_at AF239764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF239764.1 /DEF=Homo sapiens EGF-like module-containing mucin-like receptor EMR3 mRNA, complete cds. /FEA=mRNA /PROD=EGF-like module-containing mucin-like receptorEMR3 /DB_XREF=gi:13183148 /UG=Hs.326777 Homo sapiens EGF-like module-containing mucin-like receptor EMR3 mRNA, complete cds /FL=gb:AF239764.1 AF239764 egf-like module containing, mucin-like, hormone receptor-like 3 EMR3 84658 NM_001289158 /// NM_001289159 /// NM_032571 /// NM_152939 /// XM_005260118 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210726_at J04449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04449.1 /DEF=Homo sapiens (clone NF 10) cytochrome P-450 nifedipine oxidase mRNA, complete cds. /FEA=mRNA /PROD=cytochrome P450 nifedipine oxidase /DB_XREF=gi:510085 /UG=Hs.329704 cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 /FL=gb:J04449.1 J04449 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A4 1576 NM_001202855 /// NM_001202856 /// NM_001202857 /// NM_017460 0006629 // lipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // inferred from mutant phenotype /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0008209 // androgen metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0036378 // calcitriol biosynthetic process from calciol // inferred from direct assay /// 0042359 // vitamin D metabolic process // inferred by curator /// 0042737 // drug catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005496 // steroid binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from direct assay /// 0033780 // taurochenodeoxycholate 6alpha-hydroxylase activity // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047638 // albendazole monooxygenase activity // inferred from electronic annotation /// 0050591 // quinine 3-monooxygenase activity // inferred from electronic annotation /// 0050649 // testosterone 6-beta-hydroxylase activity // inferred from mutant phenotype /// 0070576 // vitamin D 24-hydroxylase activity // inferred from direct assay 210727_at M26095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M26095.1 /DEF=Human calcitonin mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:177965 /UG=Hs.37058 calcitonincalcitonin-related polypeptide, alpha /FL=gb:M26095.1 gb:NM_001741.1 M26095 calcitonin-related polypeptide alpha CALCA 796 NM_001033952 /// NM_001033953 /// NM_001741 /// XM_005253134 0001935 // endothelial cell proliferation // inferred from direct assay /// 0001944 // vasculature development // inferred from direct assay /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from direct assay /// 0001984 // vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032730 // positive regulation of interleukin-1 alpha production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from direct assay /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031716 // calcitonin receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 210728_s_at M26095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M26095.1 /DEF=Human calcitonin mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:177965 /UG=Hs.37058 calcitonincalcitonin-related polypeptide, alpha /FL=gb:M26095.1 gb:NM_001741.1 M26095 calcitonin-related polypeptide alpha CALCA 796 NM_001033952 /// NM_001033953 /// NM_001741 /// XM_005253134 0001935 // endothelial cell proliferation // inferred from direct assay /// 0001944 // vasculature development // inferred from direct assay /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from direct assay /// 0001984 // vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032730 // positive regulation of interleukin-1 alpha production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from direct assay /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031716 // calcitonin receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 210729_at U32500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U32500.1 /DEF=Human type 2 neuropeptide Y receptor mRNA, complete cds. /FEA=mRNA /PROD=type 2 neuropeptide Y receptor /DB_XREF=gi:1000750 /UG=Hs.37125 neuropeptide Y receptor Y2 /FL=gb:U32500.1 gb:U36269.1 gb:U42766.1 U32500 neuropeptide Y receptor Y2 NPY2R 4887 NM_000910 /// XM_005263033 /// XM_005263034 0001662 // behavioral fear response // inferred from electronic annotation /// 0002793 // positive regulation of peptide secretion // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007626 // locomotory behavior // traceable author statement /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046903 // secretion // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210730_s_at U36269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36269.1 /DEF=Human neuropeptide Ypeptide YY Y2 receptor mRNA, complete cds. /FEA=mRNA /PROD=neuropeptide Ypeptide YY Y2 receptor /DB_XREF=gi:1063633 /UG=Hs.37125 neuropeptide Y receptor Y2 /FL=gb:U32500.1 gb:U36269.1 gb:U42766.1 U36269 neuropeptide Y receptor Y2 NPY2R 4887 NM_000910 /// XM_005263033 /// XM_005263034 0001662 // behavioral fear response // inferred from electronic annotation /// 0002793 // positive regulation of peptide secretion // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007626 // locomotory behavior // traceable author statement /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046903 // secretion // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051048 // negative regulation of secretion // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004983 // neuropeptide Y receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210731_s_at AL136105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136105 /DEF=Human DNA sequence from clone RP4-670F13 on chromosome 1q42.2-43. Contains an enolase 1, (alpha) (ENO1) pseudogene, the gene for Po66 carbohydrate binding protein similar to soluble galactoside-binding lectin 8 (galectin 8, LGALS8), the 3 end of ... /FEA=mRNA_3 /DB_XREF=gi:9801288 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342816.1 gb:AF074001.1 AL136105 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 210732_s_at AF342816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF342816.1 /DEF=Homo sapiens colorectal carcinoma-derived galectin-8 variant II mRNA, complete cds. /FEA=mRNA /PROD=colorectal carcinoma-derived galectin-8 variantII /DB_XREF=gi:13249300 /UG=Hs.4082 lectin, galactoside-binding, soluble, 8 (galectin 8) /FL=gb:AF342816.1 gb:AF074001.1 AF342816 lectin, galactoside-binding, soluble, 8 LGALS8 3964 NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 210733_at AF130055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130055.1 /DEF=Homo sapiens clone FLB4941 PRO1292 mRNA, complete cds. /FEA=mRNA /PROD=PRO1292 /DB_XREF=gi:11493416 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:AF130055.1 AF130055 translocation associated membrane protein 1 TRAM1 23471 NM_014294 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210734_x_at M64240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M64240.1 /DEF=Human helix-loop-helix zipper protein (max) mRNA, complete cds. /FEA=mRNA /GEN=max; max /PROD=helix-loop-helix zipper protein; helix-loop-helix zipper protein /DB_XREF=gi:187390 /UG=Hs.42712 MAX protein /FL=gb:BC004516.1 gb:M64240.1 M64240 MYC associated factor X MAX 4149 NM_001271068 /// NM_001271069 /// NM_002382 /// NM_145112 /// NM_145113 /// NM_145114 /// NM_145116 /// NM_197957 /// NR_073137 /// NR_073138 /// XR_429315 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 210735_s_at BC000278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000278.1 /DEF=Homo sapiens, Similar to carbonic anhydrase XII, clone MGC:1792, mRNA, complete cds. /FEA=mRNA /PROD=Similar to carbonic anhydrase XII /DB_XREF=gi:12653028 /UG=Hs.5338 carbonic anhydrase XII /FL=gb:BC000278.1 BC000278 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210736_x_at U46746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46746.1 /DEF=Human dystrobrevin-epsilon mRNA, complete cds. /FEA=mRNA /PROD=dystrobrevin-epsilon /DB_XREF=gi:1256014 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:U46746.1 U46746 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210737_at U82467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82467.1 /DEF=Human tub homolog (TUB) mRNA, complete cds. /FEA=mRNA /GEN=TUB /PROD=tub homolog /DB_XREF=gi:2072159 /UG=Hs.54468 tubby (mouse) homolog /FL=gb:U82467.1 U82467 tubby bipartite transcription factor TUB 7275 NM_003320 /// NM_177972 /// XM_005253109 /// XM_006718303 0006909 // phagocytosis // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009584 // detection of visible light // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0044259 // multicellular organismal macromolecule metabolic process // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008020 // G-protein coupled photoreceptor activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 210738_s_at AF011390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF011390.1 /DEF=Homo sapiens pancreas sodium bicarbonate cotransporter mRNA, complete cds. /FEA=mRNA /PROD=pancreas sodium bicarbonate cotransporter /DB_XREF=gi:3298567 /UG=Hs.5462 solute carrier family 4, sodium bicarbonate cotransporter, member 4 /FL=gb:AF310248.1 gb:AF011390.1 gb:AF069510.1 gb:AF053753.1 gb:AF053754.1 AF011390 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 SLC4A4 8671 NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 210739_x_at AF069510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF069510.1 /DEF=Homo sapiens sodium bicarbonate cotransporter (NBC) mRNA, complete cds. /FEA=mRNA /GEN=NBC /PROD=sodium bicarbonate cotransporter /DB_XREF=gi:5326678 /UG=Hs.5462 solute carrier family 4, sodium bicarbonate cotransporter, member 4 /FL=gb:AF310248.1 gb:AF011390.1 gb:AF069510.1 gb:AF053753.1 gb:AF053754.1 AF069510 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 SLC4A4 8671 NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 210740_s_at AF279372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279372.1 /DEF=Homo sapiens inositol 1,3,4-trisphosphate 56-kinase mRNA, complete cds. /FEA=mRNA /PROD=inositol 1,3,4-trisphosphate 56-kinase /DB_XREF=gi:12006345 /UG=Hs.6453 inositol 1,3,4-triphosphate 56 kinase /FL=gb:AF279372.1 AF279372 inositol-tetrakisphosphate 1-kinase ITPK1 3705 NM_001142593 /// NM_001142594 /// NM_014216 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047325 // inositol tetrakisphosphate 1-kinase activity // traceable author statement /// 0052725 // inositol-1,3,4-trisphosphate 6-kinase activity // traceable author statement /// 0052726 // inositol-1,3,4-trisphosphate 5-kinase activity // traceable author statement /// 0052825 // inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity // traceable author statement /// 0052830 // inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity // traceable author statement /// 0052831 // inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity // traceable author statement /// 0052835 // inositol-3,4,6-trisphosphate 1-kinase activity // traceable author statement 210741_at AF119898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119898.1 /DEF=Homo sapiens PRO2792 mRNA, complete cds. /FEA=mRNA /PROD=PRO2792 /DB_XREF=gi:7770232 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF119898.1 AF119898 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210742_at AF064103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064103.1 /DEF=Homo sapiens Cdc14A3 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14A3 phosphatase /DB_XREF=gi:3136329 /UG=Hs.65993 CDC14 (cell division cycle 14, S. cerevisiae) homolog A /FL=gb:AF064103.1 AF064103 cell division cycle 14A CDC14A 8556 NM_003672 /// NM_033312 /// NM_033313 /// XM_005271294 /// XM_005271296 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 210743_s_at AF064103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064103.1 /DEF=Homo sapiens Cdc14A3 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14A3 phosphatase /DB_XREF=gi:3136329 /UG=Hs.65993 CDC14 (cell division cycle 14, S. cerevisiae) homolog A /FL=gb:AF064103.1 AF064103 cell division cycle 14A CDC14A 8556 NM_003672 /// NM_033312 /// NM_033313 /// XM_005271294 /// XM_005271296 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 210744_s_at M75914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M75914.1 /DEF=Human interleukin 5 receptor alpha mRNA, complete cds. /FEA=mRNA /PROD=interleukin 5 receptor alpha-chain /DB_XREF=gi:186387 /UG=Hs.68876 interleukin 5 receptor, alpha /FL=gb:M75914.1 M75914 interleukin 5 receptor, alpha IL5RA 3568 NM_000564 /// NM_001243099 /// NM_175724 /// NM_175725 /// NM_175726 /// NM_175727 /// NM_175728 /// XM_006713127 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032674 // regulation of interleukin-5 production // inferred from electronic annotation /// 0038043 // interleukin-5-mediated signaling pathway // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005895 // interleukin-5 receptor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004914 // interleukin-5 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210745_at U96173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96173.1 /DEF=Human hepatocyte nuclear factor-6 alpha (HNF6) mRNA, complete cds. /FEA=mRNA /GEN=HNF6 /PROD=hepatocyte nuclear factor-6 alpha /DB_XREF=gi:4100315 /UG=Hs.73168 one cut domain, family member 1 /FL=gb:U96173.1 U96173 one cut homeobox 1 ONECUT1 3175 NM_004498 /// NR_073510 0001889 // liver development // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210746_s_at M30646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30646.1 /DEF=Human erythrocyte membrane protein 4.2 (P4.2S) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:189435 /UG=Hs.733 erythrocyte membrane protein band 4.2 /FL=gb:M29399.1 gb:M30646.1 M30646 erythrocyte membrane protein band 4.2 EPB42 2038 NM_000119 /// NM_001114134 /// XM_005254225 0000902 // cell morphogenesis // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050801 // ion homeostasis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement 210747_at M24364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24364.1 /DEF=Human MHC class II lymphocyte antigen DQB mRNA, complete cds, haplotype DR7, DQw9. /FEA=mRNA /PROD=lymphocyte antigen /DB_XREF=gi:529041 /UG=Hs.73931 major histocompatibility complex, class II, DQ beta 1 /FL=gb:M24364.1 M24364 major histocompatibility complex, class II, DQ beta 1 HLA-DQB1 3119 NM_001243961 /// NM_001243962 /// NM_002123 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 210748_at AF116696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116696.1 /DEF=Homo sapiens PRO2239 mRNA, complete cds. /FEA=mRNA /PROD=PRO2239 /DB_XREF=gi:7959890 /UG=Hs.74711 DnaJ (Hsp40) homolog, subfamily C, member 8 /FL=gb:AF116696.1 AF116696 210749_x_at L11315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11315.1 /DEF=Homo sapiens receptor tyrosine kinase mRNA, complete cds. /FEA=mRNA /PROD=receptor tyrosine kinase /DB_XREF=gi:403386 /UG=Hs.75562 discoidin domain receptor family, member 1 /FL=gb:L11315.1 L11315 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 /// 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210750_s_at AB000277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000277.1 /DEF=Homo sapiens mRNA for DAP-1 alpha, complete cds. /FEA=mRNA /PROD=DAP-1 alpha /DB_XREF=gi:2588977 /UG=Hs.75814 discs, large (Drosophila) homolog-associated protein 1 /FL=gb:AB000277.1 AB000277 discs, large (Drosophila) homolog-associated protein 1 DLGAP1 9229 NM_001003809 /// NM_001242761 /// NM_001242762 /// NM_001242763 /// NM_001242764 /// NM_001242765 /// NM_001242766 /// NM_004746 /// XM_005258171 /// XM_005258172 /// XM_005258173 /// XM_005258174 /// XM_005258175 /// XM_005258176 /// XM_006722367 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210751_s_at D31815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D31815.1 /DEF=Human mRNA for SMP-30 (senescence marker protein-30), complete cds. /FEA=mRNA /PROD=SMP-30 /DB_XREF=gi:1072311 /UG=Hs.77854 regucalcin (senescence marker protein-30) /FL=gb:D31815.1 gb:AB028125.1 D31815 regucalcin RGN 9104 NM_001282848 /// NM_001282849 /// NM_004683 /// NM_152869 /// XM_006724567 /// XM_006724568 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0019853 // L-ascorbic acid biosynthetic process // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050848 // regulation of calcium-mediated signaling // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004341 // gluconolactonase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210752_s_at AF213666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF213666.1 /DEF=Homo sapiens bHLHZip transcription factor BIGMAX alpha mRNA, complete cds. /FEA=mRNA /PROD=bHLHZip transcription factor BIGMAX alpha /DB_XREF=gi:11761691 /UG=Hs.78185 MAX-like bHLHZIP protein /FL=gb:AF213666.1 AF213666 MLX, MAX dimerization protein MLX 6945 NM_170607 /// NM_198204 /// NM_198205 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 210753_s_at AF037334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037334.1 /DEF=Homo sapiens Eph-like receptor tyrosine kinase hEphB1d (EphB1) mRNA, complete cds. /FEA=mRNA /GEN=EphB1 /PROD=Eph-like receptor tyrosine kinase hEphB1d /DB_XREF=gi:2739209 /UG=Hs.78436 EphB1 /FL=gb:AF037334.1 AF037334 EPH receptor B1 EPHB1 2047 NM_004441 0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210754_s_at M79321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M79321.1 /DEF=Human Lyn B protein mRNA, complete cds. /FEA=mRNA /PROD=Lyn B protein /DB_XREF=gi:187270 /UG=Hs.80887 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog /FL=gb:M79321.1 M79321 LYN proto-oncogene, Src family tyrosine kinase LYN 4067 NM_001111097 /// NM_002350 /// XM_005251233 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // traceable author statement /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // traceable author statement /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002576 // platelet degranulation // inferred from sequence or structural similarity /// 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from sequence or structural similarity /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred by curator /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045646 // regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070304 // positive regulation of stress-activated protein kinase signaling cascade // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070447 // positive regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0070667 // negative regulation of mast cell proliferation // inferred from sequence or structural similarity /// 0070668 // positive regulation of mast cell proliferation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090025 // regulation of monocyte chemotaxis // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034666 // integrin alpha2-beta1 complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation 210755_at U46010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46010.1 /DEF=Human HGF agonistantagonist mRNA, complete cds. /FEA=mRNA /PROD=HGF agonistantagonist /DB_XREF=gi:1378041 /UG=Hs.809 hepatocyte growth factor (hepapoietin A; scatter factor) /FL=gb:U46010.1 U46010 hepatocyte growth factor (hepapoietin A; scatter factor) HGF 3082 NM_000601 /// NM_001010931 /// NM_001010932 /// NM_001010933 /// NM_001010934 /// XM_006715956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210756_s_at AF308601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF308601.1 /DEF=Homo sapiens NOTCH 2 (N2) mRNA, complete cds. /FEA=mRNA /GEN=N2 /PROD=NOTCH 2 /DB_XREF=gi:11275977 /UG=Hs.8121 Notch (Drosophila) homolog 2 /FL=gb:AF308601.1 AF308601 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 210757_x_at AF188298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF188298.1 /DEF=Homo sapiens disabled 2 p93 (DAB2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=DAB2 /PROD=disabled 2 p93 /DB_XREF=gi:6176335 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:AF188298.1 AF188298 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921 DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay 210758_at AF098482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098482.1 /DEF=Homo sapiens transcriptional coactivator p52 mRNA, complete cds. /FEA=mRNA /PROD=transcriptional coactivator p52 /DB_XREF=gi:4050033 /UG=Hs.82110 PC4 and SFRS1 interacting protein 1 /FL=gb:AF098482.1 AF098482 PC4 and SFRS1 interacting protein 1 PSIP1 11168 NM_001128217 /// NM_021144 /// NM_033222 /// XM_005251355 /// XM_005251356 /// XM_005251357 /// XM_005251358 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034399 // nuclear periphery // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from sequence or structural similarity 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097100 // supercoiled DNA binding // inferred from sequence or structural similarity 210759_s_at M64992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M64992.1 /DEF=Human prosomal protein P30-33K (pros-30) mRNA, complete cds. /FEA=mRNA /GEN=pros-30 /PROD=prosomal protein P30-33K /DB_XREF=gi:190446 /UG=Hs.82159 proteasome (prosome, macropain) subunit, alpha type, 1 /FL=gb:M64992.1 M64992 proteasome (prosome, macropain) subunit, alpha type, 1 PSMA1 5682 NM_001143937 /// NM_002786 /// NM_148976 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005844 // polysome // traceable author statement /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 210760_x_at BC002656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002656.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20378, clone MGC:3840, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20378 /DB_XREF=gi:12803642 /UG=Hs.85092 thyroid hormone receptor interactor 11 /FL=gb:BC002656.1 BC002656 thyroid hormone receptor interactor 11 TRIP11 9321 NM_004239 /// XM_005268213 /// XM_005268214 /// XM_005268215 /// XM_006720321 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210761_s_at AB008790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB008790.1 /DEF=Homo sapiens mRNA for Grb7V protein, complete cds. /FEA=mRNA /GEN=grb7V /PROD=Grb7V protein /DB_XREF=gi:3256232 /UG=Hs.86859 growth factor receptor-bound protein 7 /FL=gb:AB008790.1 AB008790 growth factor receptor-bound protein 7 GRB7 2886 NM_001030002 /// NM_001242442 /// NM_001242443 /// NM_005310 /// XM_006721844 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 210762_s_at AF026219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026219.1 /DEF=Homo sapiens HP protein (HP) mRNA, complete cds. /FEA=mRNA /GEN=HP /PROD=HP protein /DB_XREF=gi:2559001 /UG=Hs.8700 deleted in liver cancer 1 /FL=gb:AF026219.1 gb:AF035119.1 gb:NM_006094.2 AF026219 DLC1 Rho GTPase activating protein DLC1 10395 NM_001164271 /// NM_006094 /// NM_024767 /// NM_182643 /// XM_005273374 /// XM_005273375 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0021575 // hindbrain morphogenesis // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction 210763_x_at AF031137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031137.1 /DEF=Homo sapiens 1C7 precursor, mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=1C7 precursor /DB_XREF=gi:2623874 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF031137.1 AF031137 natural cytotoxicity triggering receptor 3 NCR3 259197 NM_001145466 /// NM_001145467 /// NM_147130 /// XM_006715049 /// XM_006725031 /// XM_006725478 /// XM_006725692 /// XM_006725808 /// XM_006725902 /// XM_006725903 /// XM_006725989 /// XM_006726081 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210764_s_at AF003114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF003114.1 /DEF=Homo sapiens CYR61 mRNA, complete cds. /FEA=mRNA /GEN=CYR61 /DB_XREF=gi:6649848 /UG=Hs.8867 cysteine-rich, angiogenic inducer, 61 /FL=gb:AF003114.1 AF003114 cysteine-rich, angiogenic inducer, 61 CYR61 3491 NM_001554 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002041 // intussusceptive angiogenesis // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from genetic interaction /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 210765_at AF053640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053640.1 /DEF=Homo sapiens trachea cellular apoptosis susceptibility protein (CSE1) mRNA, complete cds. /FEA=mRNA /GEN=CSE1 /PROD=cellular apoptosis susceptibility protein /DB_XREF=gi:3560554 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:AF053640.1 AF053640 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 210766_s_at AF053640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF053640.1 /DEF=Homo sapiens trachea cellular apoptosis susceptibility protein (CSE1) mRNA, complete cds. /FEA=mRNA /GEN=CSE1 /PROD=cellular apoptosis susceptibility protein /DB_XREF=gi:3560554 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:AF053640.1 AF053640 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 210767_at BC003112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003112.1 /DEF=Homo sapiens, Similar to Neurofibromatosis 2, clone MGC:2241, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Neurofibromatosis 2 /DB_XREF=gi:13111888 /UG=Hs.902 neurofibromin 2 (bilateral acoustic neuroma) /FL=gb:BC003112.1 BC003112 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 210768_x_at AF274935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274935.1 /DEF=Homo sapiens PNAS-10 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-10 /DB_XREF=gi:12751037 /UG=Hs.93832 putative membrane protein /FL=gb:AF274935.1 AF274935 transmembrane and coiled-coil domains 1 TMCO1 54499 NM_001256164 /// NM_001256165 /// NM_019026 /// NR_045818 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210769_at U18945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18945.1 /DEF=Human cyclic nucleotide gated channel gamma subunit (Gar-1) mRNA, complete cds. /FEA=mRNA /GEN=Gar-1 /PROD=cyclic nucleotide gated channel gamma subunit /DB_XREF=gi:1143724 /UG=Hs.93909 cyclic nucleotide gated channel beta 1 /FL=gb:U18945.1 U18945 cyclic nucleotide gated channel beta 1 CNGB1 1258 NM_001135639 /// NM_001286130 /// NM_001297 /// XM_006721134 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017071 // intracellular cyclic nucleotide activated cation channel complex // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 1902495 // transmembrane transporter complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from electronic annotation /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0030552 // cAMP binding // inferred from electronic annotation /// 0030553 // cGMP binding // not recorded /// 0030553 // cGMP binding // inferred from direct assay /// 0043855 // cyclic nucleotide-gated ion channel activity // inferred from electronic annotation 210770_s_at AF004884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004884.1 /DEF=Homo sapiens neuronal calcium channel alpha 1A subunit isoform A-1 mRNA, complete cds. /FEA=mRNA /PROD=neuronal calcium channel alpha 1A subunitisoform A-1 /DB_XREF=gi:2213912 /UG=Hs.96253 calcium channel, voltage-dependent, PQ type, alpha 1A subunit /FL=gb:AF004883.1 gb:AF004884.1 gb:AB035727.2 AF004884 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit /// uncharacterized LOC100507353 CACNA1A /// LOC100507353 773 /// 100507353 NM_000068 /// NM_001127221 /// NM_001127222 /// NM_001174080 /// NM_023035 /// XR_109571 /// XR_133165 /// XR_172267 0000096 // sulfur amino acid metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021590 // cerebellum maturation // inferred from electronic annotation /// 0021679 // cerebellar molecular layer development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032353 // negative regulation of hormone biosynthetic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042133 // neurotransmitter metabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060024 // rhythmic synaptic transmission // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0019905 // syntaxin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210771_at BC000052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000052.1 /DEF=Homo sapiens, Similar to peroxisome proliferative activated receptor, alpha, clone MGC:2237, mRNA, complete cds. /FEA=mRNA /PROD=Similar to peroxisome proliferative activatedreceptor, alpha /DB_XREF=gi:12652612 /UG=Hs.998 peroxisome proliferative activated receptor, alpha /FL=gb:BC000052.1 BC000052 peroxisome proliferator-activated receptor alpha PPARA 5465 NM_001001928 /// NM_001001929 /// NM_001001930 /// NM_005036 /// NM_032644 /// XM_005261653 /// XM_005261655 /// XM_005261656 /// XM_005261657 /// XM_006724269 /// XM_006724270 /// XM_006724271 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010871 // negative regulation of receptor biosynthetic process // inferred from direct assay /// 0010887 // negative regulation of cholesterol storage // inferred from direct assay /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0015908 // fatty acid transport // traceable author statement /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035095 // behavioral response to nicotine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046321 // positive regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation /// 0072363 // regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072366 // regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0019902 // phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from electronic annotation /// 0097371 // MDM2/MDM4 family protein binding // inferred from electronic annotation 210772_at M88107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M88107.1 /DEF=Human formyl peptide receptor (FPR2) mRNA, complete cds. /FEA=mRNA /GEN=FPR2 /PROD=formyl peptide receptor /DB_XREF=gi:189862 /UG=Hs.99855 formyl peptide receptor-like 1 /FL=gb:M76672.1 gb:M84562.1 gb:M88107.1 gb:U81501.1 gb:AF054013.1 gb:NM_001462.1 M88107 formyl peptide receptor 2 FPR2 2358 NM_001005738 /// NM_001462 /// XM_006723120 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 210773_s_at U81501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U81501.1 /DEF=Human lipoxin A4 receptor mRNA, complete cds. /FEA=mRNA /PROD=lipoxin A4 receptor /DB_XREF=gi:1916075 /UG=Hs.99855 formyl peptide receptor-like 1 /FL=gb:M76672.1 gb:M84562.1 gb:M88107.1 gb:U81501.1 gb:AF054013.1 gb:NM_001462.1 U81501 formyl peptide receptor 2 FPR2 2358 NM_001005738 /// NM_001462 /// XM_006723120 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 210774_s_at AL162047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL162047.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762E1112 (from clone DKFZp762E1112); complete cds. /FEA=mRNA /GEN=DKFZp762E1112 /PROD=hypothetical protein /DB_XREF=gi:7328089 /UG=Hs.99908 nuclear receptor coactivator 4 /FL=gb:AL162047.1 AL162047 nuclear receptor coactivator 4 NCOA4 8031 NM_001145260 /// NM_001145261 /// NM_001145262 /// NM_001145263 /// NM_005437 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008584 // male gonad development // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // traceable author statement 0003713 // transcription coactivator activity // non-traceable author statement /// 0050681 // androgen receptor binding // non-traceable author statement 210775_x_at AB015653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB015653.1 /DEF=Homo sapiens mRNA for caspase-9 beta, complete cds. /FEA=mRNA /PROD=caspase-9 beta /DB_XREF=gi:5103139 /UG=Hs.100641 caspase 9, apoptosis-related cysteine protease /FL=gb:AF093130.1 gb:AF110376.1 gb:AB015653.1 gb:AB020979.1 AB015653 caspase 9, apoptosis-related cysteine peptidase CASP9 842 NM_001229 /// NM_001278054 /// NM_032996 /// NR_102732 /// NR_102733 /// XM_005246014 /// XR_426635 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030220 // platelet formation // traceable author statement /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay 210776_x_at M31222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31222.1 /DEF=Human e12 protein (E2A) mRNA, complete cds. /FEA=mRNA /GEN=TCF3 /DB_XREF=gi:181905 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) /FL=gb:M31222.1 M31222 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 210778_s_at BC002713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002713.1 /DEF=Homo sapiens, Similar to Mad4 homolog, clone MGC:3542, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Mad4 homolog /DB_XREF=gi:12803750 /UG=Hs.102402 Mad4 homolog /FL=gb:BC002713.1 BC002713 microRNA 4800 /// MAX dimerization protein 4 MIR4800 /// MXD4 10608 /// 100616358 NM_006454 /// NR_039964 /// XR_427467 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 210779_x_at AB037701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB037701.1 /DEF=Homo sapiens SIP1-beta mRNA for SMN interacting protein1-beta, complete cds. /FEA=mRNA /GEN=SIP1-beta /PROD=SMN interacting protein1-beta /DB_XREF=gi:9650992 /UG=Hs.102456 survival of motor neuron protein interacting protein 1 /FL=gb:AB037701.1 AB037701 gem (nuclear organelle) associated protein 2 GEMIN2 8487 NM_001009182 /// NM_001009183 /// NM_003616 0000245 // spliceosomal complex assembly // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210780_at AB006589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006589.1 /DEF=Homo sapiens mRNA for estrogen receptor beta cx, complete cds. /FEA=mRNA /PROD=estrogen receptor beta cx /DB_XREF=gi:3345671 /UG=Hs.103504 estrogen receptor 2 (ER beta) /FL=gb:AB006589.1 AB006589 estrogen receptor 2 (ER beta) ESR2 2100 NM_001040275 /// NM_001040276 /// NM_001214902 /// NM_001214903 /// NM_001271876 /// NM_001271877 /// NM_001291712 /// NM_001291723 /// NM_001437 /// NR_073496 /// NR_073497 /// NR_073505 /// XM_006720075 /// XM_006720076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005496 // steroid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030284 // estrogen receptor activity // traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // non-traceable author statement 210781_x_at AF015731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015731.1 /DEF=Homo sapiens NMDAR1 subunit isoform 4b (hNMDAR1-4b) mRNA, complete cds. /FEA=mRNA /GEN=hNMDAR1-4b /PROD=NMDAR1 subunit isoform 4b /DB_XREF=gi:2343288 /UG=Hs.105 glutamate receptor, ionotropic, N-methyl D-aspartate 1 /FL=gb:AF015731.1 AF015731 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRIN1 2902 NM_000832 /// NM_001185090 /// NM_001185091 /// NM_007327 /// NM_021569 /// XM_005266071 /// XM_005266072 /// XM_005266073 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008355 // olfactory learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010646 // regulation of cell communication // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0018964 // propylene metabolic process // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021586 // pons maturation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043083 // synaptic cleft // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016595 // glutamate binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 210782_x_at L05666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L05666.1 /DEF=Homo sapiens NMDA receptor subunit (NR1) mRNA, complete cds. /FEA=mRNA /PROD=NMDA receptor /DB_XREF=gi:307302 /UG=Hs.105 glutamate receptor, ionotropic, N-methyl D-aspartate 1 /FL=gb:NM_000832.4 gb:L13266.1 gb:L05666.1 L05666 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRIN1 2902 NM_000832 /// NM_001185090 /// NM_001185091 /// NM_007327 /// NM_021569 /// XM_005266071 /// XM_005266072 /// XM_005266073 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008355 // olfactory learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010646 // regulation of cell communication // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0018964 // propylene metabolic process // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021586 // pons maturation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043083 // synaptic cleft // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016595 // glutamate binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 210783_x_at D86586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86586.1 /DEF=Homo sapiens mRNA for SCGF-beta, complete cds. /FEA=mRNA /PROD=SCGF-beta /DB_XREF=gi:2257694 /UG=Hs.105927 stem cell growth factor; lymphocyte secreted C-type lectin /FL=gb:D86586.1 D86586 C-type lectin domain family 11, member A CLEC11A 6320 NM_002975 0008284 // positive regulation of cell proliferation // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0008083 // growth factor activity // inferred from direct assay /// 0030246 // carbohydrate binding // non-traceable author statement 210784_x_at AF009634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009634.1 /DEF=Homo sapiens clone 17.6 immunoglobulin-like transcript 5 protein mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 5 protein /DB_XREF=gi:2662427 /UG=Hs.105928 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 /FL=gb:AF009634.1 gb:AF009636.1 gb:AF009640.1 AF009634 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 LILRB3 11025 NM_001081450 /// NM_006864 /// XM_006722983 /// XM_006722984 /// XM_006722985 /// XM_006726175 /// XM_006726176 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210785_s_at AB035482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035482.1 /DEF=Homo sapiens mRNA for ICB-1beta, complete cds. /FEA=mRNA /PROD=ICB-1beta /DB_XREF=gi:8272423 /UG=Hs.10649 basement membrane-induced gene /FL=gb:AB035482.1 AB035482 thymocyte selection associated family member 2 THEMIS2 9473 NM_001039477 /// NM_001105556 /// NM_001286113 /// NM_001286115 /// NM_004848 /// XM_005246041 /// XM_006711050 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210786_s_at M93255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M93255.1 /DEF=Human FLI-1 mRNA, complete cds for two alternate splicings. /FEA=mRNA /GEN=FLI-1; FLI-1 /PROD=FLI-1 /DB_XREF=gi:182659 /UG=Hs.108043 Friend leukemia virus integration 1 /FL=gb:M93255.1 M93255 Fli-1 proto-oncogene, ETS transcription factor FLI1 2313 NM_001167681 /// NM_001271010 /// NM_001271012 /// NM_002017 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007599 // hemostasis // traceable author statement /// 0008015 // blood circulation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0035855 // megakaryocyte development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210787_s_at AF140507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF140507.1 /DEF=Homo sapiens Ca2+calmodulin-dependent protein kinase kinase beta (CAMKKB) mRNA, complete cds. /FEA=mRNA /GEN=CAMKKB /PROD=Ca2+calmodulin-dependent protein kinase kinasebeta /DB_XREF=gi:4877950 /UG=Hs.108708 calciumcalmodulin-dependent protein kinase kinase 2, beta /FL=gb:AF140507.1 AF140507 calcium/calmodulin-dependent protein kinase kinase 2, beta CAMKK2 10645 NM_001270485 /// NM_001270486 /// NM_006549 /// NM_153499 /// NM_153500 /// NM_172214 /// NM_172215 /// NM_172216 /// NM_172226 /// XM_005253822 /// XM_005253823 /// XM_005253824 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0045859 // regulation of protein kinase activity // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210788_s_at AF126782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF126782.1 /DEF=Homo sapiens retinal short-chain dehydrogenasereductase retSDR4 mRNA, complete cds. /FEA=mRNA /PROD=retinal short-chain dehydrogenasereductaseretSDR4 /DB_XREF=gi:6318547 /UG=Hs.109201 CGI-86 protein /FL=gb:AF126782.1 AF126782 dehydrogenase/reductase (SDR family) member 7 DHRS7 51635 NM_016029 /// XM_005267757 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 210789_x_at L00692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L00692.1 /DEF=Human carcinoembryonic antigen (CGM1) mRNA, complete cds. /FEA=mRNA /GEN=CGM1 /PROD=carcinoembryonic antigen /DB_XREF=gi:180226 /UG=Hs.11 carcinoembryonic antigen-related cell adhesion molecule 3 /FL=gb:L00692.1 L00692 carcinoembryonic antigen-related cell adhesion molecule 3 CEACAM3 1084 NM_001277163 /// NM_001815 /// NR_102333 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210790_s_at BC003658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003658.1 /DEF=Homo sapiens, SAR1 protein, clone MGC:4824, mRNA, complete cds. /FEA=mRNA /PROD=SAR1 protein /DB_XREF=gi:13177777 /UG=Hs.110796 SAR1 protein /FL=gb:BC003658.1 BC003658 secretion associated, Ras related GTPase 1A SAR1A 56681 NM_001142648 /// NM_020150 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 210791_s_at BC000277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000277.1 /DEF=Homo sapiens, clone MGC:1892, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1892) /DB_XREF=gi:12802987 /UG=Hs.111138 KIAA0712 gene product /FL=gb:BC000277.1 BC000277 Rho GTPase activating protein 32 ARHGAP32 9743 NM_001142685 /// NM_014715 /// XM_005271736 /// XM_006718947 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 210792_x_at AF033111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF033111.1 /DEF=Homo sapiens Siva-2 mRNA, complete cds. /FEA=mRNA /PROD=Siva-2 /DB_XREF=gi:5737690 /UG=Hs.112058 CD27-binding (Siva) protein /FL=gb:NM_021709.1 gb:AF033111.1 AF033111 SIVA1, apoptosis-inducing factor SIVA1 10572 NM_006427 /// NM_021709 0006915 // apoptotic process // inferred from electronic annotation /// 0006924 // activation-induced cell death of T cells // inferred from direct assay /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001618 // virus receptor activity // inferred from sequence or structural similarity /// 0005175 // CD27 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210793_s_at U41815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U41815.1 /DEF=Human nucleoporin 98 (NUP98) mRNA, complete cds. /FEA=mRNA /GEN=NUP98 /PROD=nucleoporin 98 /DB_XREF=gi:1184172 /UG=Hs.112255 nucleoporin 98kD /FL=gb:U41815.1 U41815 nucleoporin 98kDa NUP98 4928 NM_005387 /// NM_016320 /// NM_139131 /// NM_139132 /// XM_005252950 /// XM_006718240 /// XM_006718241 /// XM_006718242 /// XR_428845 0000059 // protein import into nucleus, docking // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006999 // nuclear pore organization // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0017056 // structural constituent of nuclear pore // non-traceable author statement /// 0042277 // peptide binding // inferred from electronic annotation 210794_s_at AF119863 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF119863.1 /DEF=Homo sapiens PRO2160 mRNA, complete cds. /FEA=mRNA /PROD=PRO2160 /DB_XREF=gi:7770162 /UG=Hs.112844 maternally expressed 3 /FL=gb:AF119863.1 AF119863 maternally expressed 3 (non-protein coding) MEG3 55384 NR_002766 /// NR_003530 /// NR_003531 /// NR_033358 /// NR_033359 /// NR_033360 /// NR_046464 /// NR_046465 /// NR_046466 /// NR_046467 /// NR_046468 /// NR_046469 /// NR_046470 /// NR_046471 /// NR_046472 /// NR_046473 210795_s_at AF119863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119863.1 /DEF=Homo sapiens PRO2160 mRNA, complete cds. /FEA=mRNA /PROD=PRO2160 /DB_XREF=gi:7770162 /UG=Hs.112844 maternally expressed 3 /FL=gb:AF119863.1 AF119863 210796_x_at D86359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86359.1 /DEF=Homo sapiens mRNA for CD33L2, complete cds. /FEA=mRNA /PROD=CD33L2 /DB_XREF=gi:2913996 /UG=Hs.117992 sialic acid binding Ig-like lectin 6 /FL=gb:D86359.1 D86359 sialic acid binding Ig-like lectin 6 SIGLEC6 946 NM_001177547 /// NM_001177548 /// NM_001177549 /// NM_001245 /// NM_198845 /// NM_198846 /// XR_243971 /// XR_243972 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210797_s_at AF063612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF063612.1 /DEF=Homo sapiens 2-5oligoadenylate synthetase-related protein p30 (OASL) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=OASL /PROD=2-5oligoadenylate synthetase-related proteinp30 /DB_XREF=gi:4731858 /UG=Hs.118633 2-5oligoadenylate synthetase-like /FL=gb:AF063612.1 AF063612 2'-5'-oligoadenylate synthetase-like OASL 8638 NM_001261825 /// NM_003733 /// NM_198213 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // traceable author statement 210798_x_at AB008047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB008047.1 /DEF=Homo sapiens sMAP mRNA for small MBL-associated protein, complete cds. /FEA=mRNA /GEN=sMAP /PROD=small MBL-associated protein /DB_XREF=gi:5002493 /UG=Hs.119983 mannan-binding lectin serine protease 2 /FL=gb:AB008047.1 AB008047 mannan-binding lectin serine peptidase 2 MASP2 10747 NM_006610 /// NM_139208 0001867 // complement activation, lectin pathway // inferred from direct assay /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001855 // complement component C4b binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210799_at M81590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81590.1 /DEF=Homo sapiens serotonin 1D receptor (5-HT1D~) mRNA, complete cds. /FEA=mRNA /GEN=5-HT1D~ /PROD=serotonin 1D receptor /DB_XREF=gi:338025 /UG=Hs.123016 5-hydroxytryptamine (serotonin) receptor 1B /FL=gb:M81590.1 gb:NM_000863.1 M81590 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled HTR1B 3351 NM_000863 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007198 // adenylate cyclase-inhibiting serotonin receptor signaling pathway // inferred from direct assay /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014063 // negative regulation of serotonin secretion // inferred from sequence or structural similarity /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046849 // bone remodeling // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from direct assay /// 0071502 // cellular response to temperature stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from electronic annotation /// 0051378 // serotonin binding // inferred from electronic annotation 210800_at BC005236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005236.1 /DEF=Homo sapiens, clone MGC:12262, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12262) /DB_XREF=gi:13528875 /UG=Hs.125565 translocase of inner mitochondrial membrane 8 (yeast) homolog A /FL=gb:BC005236.1 BC005236 translocase of inner mitochondrial membrane 8 homolog A (yeast) TIMM8A 1678 NM_001145951 /// NM_004085 /// NM_032696 /// XM_005262092 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072321 // chaperone-mediated protein transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 210801_at BC002841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002841.1 /DEF=Homo sapiens, Similar to putative dimethyladenosine transferase, clone MGC:3382, mRNA, complete cds. /FEA=mRNA /PROD=Similar to putative dimethyladenosinetransferase /DB_XREF=gi:12803982 /UG=Hs.125819 putative dimethyladenosine transferase /FL=gb:BC002841.1 BC002841 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) DIMT1 27292 NM_014473 0000154 // rRNA modification // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016433 // rRNA (adenine) methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0052909 // 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity // inferred from electronic annotation 210802_s_at BC002841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002841.1 /DEF=Homo sapiens, Similar to putative dimethyladenosine transferase, clone MGC:3382, mRNA, complete cds. /FEA=mRNA /PROD=Similar to putative dimethyladenosinetransferase /DB_XREF=gi:12803982 /UG=Hs.125819 putative dimethyladenosine transferase /FL=gb:BC002841.1 BC002841 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) DIMT1 27292 NM_014473 0000154 // rRNA modification // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016433 // rRNA (adenine) methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0052909 // 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity // inferred from electronic annotation 210803_at AF201385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201385.1 /DEF=Homo sapiens mitochondrial thioredoxin reductase (TRXR2A) mRNA, complete cds, alternatively spliced; nuclear gene for mitochondrial product. /FEA=mRNA /GEN=TRXR2A /PROD=mitochondrial thioredoxin reductase /DB_XREF=gi:12043737 /UG=Hs.12971 thioredoxin reductase beta /FL=gb:AF201385.1 AF201385 thioredoxin reductase 2 TXNRD2 10587 NM_001282512 /// NM_006440 /// NM_145747 /// NM_145748 0000305 // response to oxygen radical // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0004791 // thioredoxin-disulfide reductase activity // not recorded /// 0004791 // thioredoxin-disulfide reductase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 210804_x_at AF128524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF128524.1 /DEF=Homo sapiens sodium-calcium exchanger isoform NCX1.7 precursor (SLC8A1) mRNA, complete cds. /FEA=mRNA /GEN=SLC8A1 /PROD=sodium-calcium exchanger isoform NCX1.7precursor /DB_XREF=gi:4589138 /UG=Hs.129763 solute carrier family 8 (sodiumcalcium exchanger), member 1 /FL=gb:AF128524.1 gb:AF108388.1 AF128524 solute carrier family 8 (sodium/calcium exchanger), member 1 SLC8A1 6546 NM_001112800 /// NM_001112801 /// NM_001112802 /// NM_001252624 /// NM_021097 /// XM_005264512 /// XM_005264513 /// XM_005264514 /// XM_006712080 /// XM_006712081 /// XM_006712082 /// XM_006712083 /// XM_006712084 /// XM_006712085 /// XM_006712086 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred by curator /// 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014829 // vascular smooth muscle contraction // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044557 // relaxation of smooth muscle // inferred from sequence or structural similarity /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // inferred by curator /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // traceable author statement /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071436 // sodium ion export // inferred from direct assay /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity /// 0097369 // sodium ion import // inferred from direct assay /// 1901660 // calcium ion export // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0005432 // calcium:sodium antiporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 210805_x_at U19601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19601.1 /DEF=Human (AML1B) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:1932819 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:U19601.1 gb:D43969.1 U19601 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 210806_at AL136808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136808.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N2321 (from clone DKFZp434N2321); complete cds. /FEA=mRNA /GEN=DKFZp434N2321 /PROD=hypothetical protein /DB_XREF=gi:12053126 /UG=Hs.131525 KIAA0998 protein /FL=gb:AL136808.1 AL136808 tubulin tyrosine ligase-like family, member 5 TTLL5 23093 NM_015072 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 210807_s_at AF049608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF049608.1 /DEF=Homo sapiens monocarboxylate transporter 2 (MCT2) mRNA, complete cds. /FEA=mRNA /GEN=MCT2 /PROD=monocarboxylate transporter 2 /DB_XREF=gi:3834394 /UG=Hs.132183 solute carrier family 16 (monocarboxylic acid transporters), member 7 /FL=gb:AF049608.1 AF049608 solute carrier family 16 (monocarboxylate transporter), member 7 SLC16A7 9194 NM_001270622 /// NM_001270623 /// NM_004731 /// NR_073055 /// NR_073056 /// XM_005269231 /// XM_006719693 0006810 // transport // inferred from electronic annotation /// 0006848 // pyruvate transport // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // inferred from electronic annotation /// 0035873 // lactate transmembrane transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1901475 // pyruvate transmembrane transport // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005477 // pyruvate secondary active transmembrane transporter activity // traceable author statement /// 0015129 // lactate transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0050833 // pyruvate transmembrane transporter activity // inferred from direct assay 210808_s_at AF166327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF166327.1 /DEF=Homo sapiens NADPH oxidase homolog 1 long form (NOH1) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=NOH1 /PROD=NADPH oxidase homolog 1 long form /DB_XREF=gi:6672077 /UG=Hs.132370 NADPH oxidase 1 /FL=gb:AF166327.1 AF166327 NADPH oxidase 1 NOX1 27035 NM_001271815 /// NM_007052 /// NM_013954 /// NM_013955 0001525 // angiogenesis // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred by curator /// 0006746 // FADH2 metabolic process // non-traceable author statement /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006811 // ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009268 // response to pH // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from expression pattern /// 0015992 // proton transport // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042743 // hydrogen peroxide metabolic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from direct assay /// 0072592 // oxygen metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016175 // superoxide-generating NADPH oxidase activity // inferred by curator /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030171 // voltage-gated proton channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0050661 // NADP binding // inferred by curator 210809_s_at D13665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13665.1 /DEF=Homo sapiens osf-2 mRNA for osteoblast specific factor 2 (OSF-2p1), complete cds. /FEA=mRNA /GEN=osf-2 /PROD=osteoblast specific factor 2 /DB_XREF=gi:393318 /UG=Hs.136348 osteoblast specific factor 2 (fasciclin I-like) /FL=gb:D13665.1 D13665 periostin, osteoblast specific factor POSTN 10631 NM_001135934 /// NM_001135935 /// NM_001135936 /// NM_001286665 /// NM_001286666 /// NM_001286667 /// NM_006475 /// XM_005266231 /// XM_005266232 0001501 // skeletal system development // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from sequence or structural similarity 210810_s_at AF142501 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF142501.1 /DEF=Homo sapiens glycine transporter type-2 mRNA, complete cds. /FEA=mRNA /PROD=glycine transporter type-2 /DB_XREF=gi:4689409 /UG=Hs.136557 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 /FL=gb:AF117999.1 gb:AF085412.1 gb:AF142501.1 gb:NM_004211.1 AF142501 solute carrier family 6 (neurotransmitter transporter), member 5 SLC6A5 9152 NM_004211 /// XM_005253225 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0036233 // glycine import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0060012 // synaptic transmission, glycinergic // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015375 // glycine:sodium symporter activity // inferred from direct assay 210811_s_at BC000979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000979.2 /DEF=Homo sapiens, Similar to hypothetical protein, clone MGC:5278, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein /DB_XREF=gi:12803028 /UG=Hs.143187 hypothetical protein /FL=gb:BC000979.2 BC000979 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 DDX49 54555 NM_019070 /// NR_033677 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210812_at BC005259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005259.1 /DEF=Homo sapiens, Similar to X-ray repair complementing defective repair in Chinese hamster cells 4, clone MGC:12297, mRNA, complete cds. /FEA=mRNA /PROD=Similar to X-ray repair complementing defectiverepair in Chinese hamster cells 4 /DB_XREF=gi:13528935 /UG=Hs.150930 X-ray repair complementing defective repair in Chinese hamster cells 4 /FL=gb:BC005259.1 BC005259 X-ray repair complementing defective repair in Chinese hamster cells 4 XRCC4 7518 NM_003401 /// NM_022406 /// NM_022550 /// XM_005248595 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // non-traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from direct assay /// 0051351 // positive regulation of ligase activity // inferred from direct assay /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032807 // DNA ligase IV complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from direct assay 210813_s_at BC005259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005259.1 /DEF=Homo sapiens, Similar to X-ray repair complementing defective repair in Chinese hamster cells 4, clone MGC:12297, mRNA, complete cds. /FEA=mRNA /PROD=Similar to X-ray repair complementing defectiverepair in Chinese hamster cells 4 /DB_XREF=gi:13528935 /UG=Hs.150930 X-ray repair complementing defective repair in Chinese hamster cells 4 /FL=gb:BC005259.1 BC005259 X-ray repair complementing defective repair in Chinese hamster cells 4 XRCC4 7518 NM_003401 /// NM_022406 /// NM_022550 /// XM_005248595 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // non-traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from direct assay /// 0051351 // positive regulation of ligase activity // inferred from direct assay /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032807 // DNA ligase IV complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from direct assay 210814_at U47050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U47050.1 /DEF=Human putative calcium influx channel (htrp3) mRNA, complete cds. /FEA=mRNA /GEN=htrp3 /PROD=calcium influx channel /DB_XREF=gi:2295902 /UG=Hs.150981 transient receptor potential channel 3 /FL=gb:U47050.1 U47050 transient receptor potential cation channel, subfamily C, member 3 TRPC3 7222 NM_001130698 /// NM_003305 /// XM_006714295 /// XM_006714296 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // traceable author statement /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0033198 // response to ATP // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // traceable author statement /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 210815_s_at U17473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17473.1 /DEF=Human calcitonin-like receptor mRNA, complete cds. /FEA=mRNA /PROD=calcitonin-like receptor /DB_XREF=gi:662328 /UG=Hs.152175 calcitonin receptor-like /FL=gb:U17473.1 U17473 calcitonin receptor-like CALCRL 10203 NM_001271751 /// NM_005795 /// XM_005246231 /// XM_005246232 /// XM_005246234 0001525 // angiogenesis // inferred from direct assay /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0071329 // cellular response to sucrose stimulus // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001605 // adrenomedullin receptor activity // inferred from direct assay /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004948 // calcitonin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from direct assay 210816_s_at BC000021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000021.1 /DEF=Homo sapiens, Similar to cytochrome b-561, clone MGC:3308, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cytochrome b-561 /DB_XREF=gi:12652560 /UG=Hs.153028 cytochrome b-561 /FL=gb:BC000021.1 BC000021 cytochrome b561 CYB561 1534 NM_001017916 /// NM_001017917 /// NM_001017918 /// NM_001915 /// XM_005257090 /// XM_005257091 /// XM_005257092 /// XM_006721727 0022900 // electron transport chain // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000293 // ferric-chelate reductase activity // inferred from sequence or structural similarity /// 0022865 // transmembrane electron transfer carrier // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210817_s_at BC004130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004130.1 /DEF=Homo sapiens, nuclear domain 10 protein, clone MGC:1399, mRNA, complete cds. /FEA=mRNA /PROD=nuclear domain 10 protein /DB_XREF=gi:13278698 /UG=Hs.154230 nuclear domain 10 protein /FL=gb:BC004130.1 BC004130 calcium binding and coiled-coil domain 2 CALCOCO2 10241 NM_001261390 /// NM_001261391 /// NM_001261393 /// NM_001261395 /// NM_005831 0016032 // viral process // traceable author statement /// 0034341 // response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 210818_s_at AF026199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026199.1 /DEF=Homo sapiens transcription regulator protein (BACH1) mRNA, complete cds. /FEA=mRNA /GEN=BACH1 /PROD=transcription regulator protein /DB_XREF=gi:2565399 /UG=Hs.154276 BTB and CNC homology 1, basic leucine zipper transcription factor 1 /FL=gb:AF026199.1 AF026199 BTB and CNC homology 1, basic leucine zipper transcription factor 1 /// GRIK1 antisense RNA 2 BACH1 /// GRIK1-AS2 571 /// 100379661 NM_001011545 /// NM_001186 /// NM_206866 /// NR_027655 /// NR_033368 /// XM_005261012 /// XM_005261013 /// XM_005261014 /// XM_006724034 /// XR_430352 /// XR_430353 /// XR_430354 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000117 // regulation of transcription involved in G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0020037 // heme binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210819_x_at AB041844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB041844.1 /DEF=Homo sapiens mRNA for type II iodothyronine deiodinase, complete cds. /FEA=mRNA /PROD=type II iodothyronine deiodinase /DB_XREF=gi:10863066 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:AB041844.1 AB041844 deiodinase, iodothyronine, type II DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 210820_x_at AL136647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136647.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C1362 (from clone DKFZp564C1362); complete cds. /FEA=mRNA /GEN=DKFZp564C1362 /PROD=hypothetical protein /DB_XREF=gi:12052819 /UG=Hs.157113 coenzyme Q, 7 (rat, yeast) homolog /FL=gb:AL136647.1 AL136647 coenzyme Q7 homolog, ubiquinone (yeast) COQ7 10229 NM_001190983 /// NM_016138 /// XM_005255033 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 210821_x_at BC002703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002703.1 /DEF=Homo sapiens, centromere protein A (17kD), clone MGC:3892, mRNA, complete cds. /FEA=mRNA /PROD=centromere protein A (17kD) /DB_XREF=gi:12803732 /UG=Hs.1594 centromere protein A (17kD) /FL=gb:BC002703.1 BC002703 centromere protein A CENPA 1058 NM_001042426 /// NM_001809 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0051382 // kinetochore assembly // inferred from direct assay /// 0071459 // protein localization to chromosome, centromeric region // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000778 // condensed nuclear chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000939 // condensed chromosome inner kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210822_at U72513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U72513.1 /DEF=Human RPL13-2 pseudogene mRNA, complete cds. /FEA=mRNA /PROD=RPL13-2 /DB_XREF=gi:1673516 /UG=Hs.159486 Human RPL13-2 pseudogene mRNA, complete cds /FL=gb:U72513.1 U72513 leucine rich repeat containing 23 /// ribosomal protein L13 pseudogene 5 LRRC23 /// RPL13P5 10233 /// 283345 NM_001135217 /// NM_006992 /// NM_201650 /// NR_002803 210823_s_at U40317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U40317.1 /DEF=Human protein tyrosine phosphatase PTPsigma (PTPsigma) mRNA, complete cds. /FEA=mRNA /GEN=PTPsigma /PROD=PTPsigma /DB_XREF=gi:1407624 /UG=Hs.159534 protein tyrosine phosphatase, receptor type, S /FL=gb:U40317.1 U40317 protein tyrosine phosphatase, receptor type, S PTPRS 5802 NM_002850 /// NM_130853 /// NM_130854 /// NM_130855 /// XM_005259600 /// XM_005259601 /// XM_005259606 /// XM_005259607 /// XM_005259609 /// XM_005259610 /// XM_006722808 /// XM_006722809 /// XM_006722810 /// XM_006722811 /// XM_006722812 /// XM_006722813 /// XM_006722814 /// XM_006722815 /// XM_006722816 /// XM_006722817 /// XM_006722818 /// XM_006722819 /// XM_006722820 /// XM_006722821 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 210824_at AF130103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130103.1 /DEF=Homo sapiens clone FLB2914 PRO0720 mRNA, complete cds. /FEA=mRNA /PROD=PRO0720 /DB_XREF=gi:11493509 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:AF130103.1 AF130103 210825_s_at AF130103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130103.1 /DEF=Homo sapiens clone FLB2914 PRO0720 mRNA, complete cds. /FEA=mRNA /PROD=PRO0720 /DB_XREF=gi:11493509 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:AF130103.1 AF130103 phosphatidylethanolamine binding protein 1 PEBP1 5037 NM_002567 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210826_x_at AF098533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098533.1 /DEF=Homo sapiens RAD17 isoform 3 (RAD17) mRNA, complete cds. /FEA=mRNA /GEN=RAD17 /PROD=RAD17 isoform 3 /DB_XREF=gi:4050041 /UG=Hs.16184 RAD17 (S. pombe) homolog /FL=gb:AF098533.1 AF098533 RAD17 homolog (S. pombe) RAD17 5884 NM_001278622 /// NM_002873 /// NM_133338 /// NM_133339 /// NM_133340 /// NM_133341 /// NM_133342 /// NM_133343 /// NM_133344 /// XM_005276774 0000076 // DNA replication checkpoint // traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 210827_s_at U73844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73844.1 /DEF=Homo sapiens epithelial-specific transcription factor ESE-1a (ESE-1) mRNA, complete cds. /FEA=mRNA /GEN=ESE-1 /PROD=ESE-1a /DB_XREF=gi:1841524 /UG=Hs.166096 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) /FL=gb:U73844.1 U73844 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) ELF3 1999 NM_001114309 /// NM_004433 /// XM_005244942 0001824 // blastocyst development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // inferred from expression pattern /// 0007275 // multicellular organismal development // traceable author statement /// 0008544 // epidermis development // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210828_s_at AF001307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001307.1 /DEF=Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA, splice variant, complete cds. /FEA=mRNA /GEN=ARNT /PROD=aryl hydrocarbon receptor nuclear translocator /DB_XREF=gi:2702318 /UG=Hs.166172 aryl hydrocarbon receptor nuclear translocator /FL=gb:AF001307.1 AF001307 aryl hydrocarbon receptor nuclear translocator ARNT 405 NM_001197325 /// NM_001286035 /// NM_001286036 /// NM_001668 /// NM_178426 /// NM_178427 /// XM_005245151 /// XM_005245153 /// XM_005245154 /// XM_005245157 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045821 // positive regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004874 // aryl hydrocarbon receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017162 // aryl hydrocarbon receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 210829_s_at AF077048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077048.1 /DEF=Homo sapiens single strand DNA-binding protein mRNA, complete cds. /FEA=mRNA /PROD=single strand DNA-binding protein /DB_XREF=gi:4689143 /UG=Hs.169833 single-stranded-DNA-binding protein /FL=gb:AF077048.1 AF077048 single-stranded DNA binding protein 2 SSBP2 23635 NM_001256732 /// NM_001256733 /// NM_001256734 /// NM_001256735 /// NM_001256736 /// NM_012446 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210830_s_at AF001602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001602.1 /DEF=Homo sapiens paraoxonase (PON2) mRNA, with alternatively spliced exon 3, complete cds. /FEA=mRNA /GEN=PON2 /PROD=paraoxonase /DB_XREF=gi:2228776 /UG=Hs.169857 paraoxonase 2 /FL=gb:AF001602.1 AF001602 paraoxonase 2 PON2 5445 NM_000305 /// NM_001018161 /// XM_005250453 /// XM_005250454 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004064 // arylesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210831_s_at L27489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L27489.1 /DEF=Homo sapiens prostanoid EP3-III receptor mRNA, complete cds. /FEA=mRNA /PROD=prostanoid EP3-III receptor /DB_XREF=gi:440311 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38301.1 gb:L27489.1 gb:U13215.1 L27489 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210832_x_at D38298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38298.1 /DEF=Homo sapiens mRNA for prostaglandin E receotor EP3 subtype 1b isoform, complete cds. /FEA=mRNA /PROD=prostaglandin E receotor EP3 subtype 1b isoform /DB_XREF=gi:1389573 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38298.1 D38298 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 210833_at AL031429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031429 /DEF=Human DNA sequence from clone 333A15 on chromosome 1p31.1-31.3 Contains prostaglandin E receptor (subtypes EP3e, EP3a2, EP3c), EST, STSs, GSSs and a CpG Island /FEA=mRNA_1 /DB_XREF=gi:4775605 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38299.1 gb:L27488.1 gb:U13217.1 AL031429 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 210834_s_at D38299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38299.1 /DEF=Homo sapiens mRNA for prostaglandin E receotor EP3 subtype 2 isoform, complete cds. /FEA=mRNA /PROD=prostaglandin E receotor EP3 subtype 2 isoform /DB_XREF=gi:1389574 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:D38299.1 gb:L27488.1 gb:U13217.1 D38299 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 210835_s_at AF222711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF222711.1 /DEF=Homo sapiens ribeye mRNA, complete cds. /FEA=mRNA /PROD=ribeye /DB_XREF=gi:12034652 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF222711.1 gb:NM_022802.1 AF222711 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 210836_x_at AF012073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF012073.1 /DEF=Homo sapiens cAMP-specific phosphodiesterase PDE4D5 (PDE4D) mRNA, complete cds. /FEA=mRNA /GEN=PDE4D /PROD=cAMP-specific phosphodiesterase PDE4D5 /DB_XREF=gi:2735856 /UG=Hs.172081 phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) /FL=gb:AF012073.1 AF012073 phosphodiesterase 4D, cAMP-specific PDE4D 5144 NM_001104631 /// NM_001165899 /// NM_001197218 /// NM_001197219 /// NM_001197220 /// NM_001197221 /// NM_001197222 /// NM_001197223 /// NM_006203 /// XM_005248537 /// XM_005248538 /// XM_005248540 /// XM_005248541 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0032754 // positive regulation of interleukin-5 production // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 0086024 // adrenergic receptor signaling pathway involved in positive regulation of heart rate // inferred by curator /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0030552 // cAMP binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 210837_s_at AF012074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF012074.1 /DEF=Homo sapiens cAMP-specific phosphodiesterase PDE4D2 (PDE4D) mRNA, complete cds. /FEA=mRNA /GEN=PDE4D /PROD=cAMP-specific phosphodiesterase PDE4D2 /DB_XREF=gi:2735858 /UG=Hs.172081 phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) /FL=gb:U50158.1 gb:AF012074.1 AF012074 phosphodiesterase 4D, cAMP-specific PDE4D 5144 NM_001104631 /// NM_001165899 /// NM_001197218 /// NM_001197219 /// NM_001197220 /// NM_001197221 /// NM_001197222 /// NM_001197223 /// NM_006203 /// XM_005248537 /// XM_005248538 /// XM_005248540 /// XM_005248541 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0032754 // positive regulation of interleukin-5 production // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 0086024 // adrenergic receptor signaling pathway involved in positive regulation of heart rate // inferred by curator /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0030552 // cAMP binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 210838_s_at L17075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L17075.1 /DEF=Human TGF-b superfamily receptor type I mRNA, complete cds. /FEA=mRNA /PROD=TGF-b superfamily receptor type I /DB_XREF=gi:425147 /UG=Hs.172670 activin A receptor type II-like 1 /FL=gb:L17075.1 L17075 activin A receptor type II-like 1 ACVRL1 94 NM_000020 /// NM_001077401 /// XM_005269235 0001525 // angiogenesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001936 // regulation of endothelial cell proliferation // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0001955 // blood vessel maturation // traceable author statement /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // traceable author statement /// 0006275 // regulation of DNA replication // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0008015 // blood circulation // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0032332 // positive regulation of chondrocyte differentiation // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0043535 // regulation of blood vessel endothelial cell migration // traceable author statement /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045602 // negative regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0060836 // lymphatic endothelial cell differentiation // inferred from mutant phenotype /// 0060840 // artery development // inferred from sequence or structural similarity /// 0060841 // venous blood vessel development // inferred from sequence or structural similarity /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071773 // cellular response to BMP stimulus // inferred from mutant phenotype /// 2000279 // negative regulation of DNA biosynthetic process // inferred from mutant phenotype 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from reviewed computational analysis /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 210839_s_at D45421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D45421.1 /DEF=Human mRNA for phosphodiesterase I alpha, complete cds. /FEA=mRNA /PROD=phosphodiesterase I alpha /DB_XREF=gi:662289 /UG=Hs.174185 ectonucleotide pyrophosphatasephosphodiesterase 2 (autotaxin) /FL=gb:NM_006209.1 gb:D45421.1 D45421 ectonucleotide pyrophosphatase/phosphodiesterase 2 ENPP2 5168 NM_001040092 /// NM_001130863 /// NM_006209 /// NR_045555 /// XM_006716584 /// XM_006716585 /// XM_006716586 /// XM_006716587 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from direct assay /// 0034638 // phosphatidylcholine catabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // traceable author statement /// 0004551 // nucleotide diphosphatase activity // traceable author statement /// 0004622 // lysophospholipase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008134 // transcription factor binding // traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // traceable author statement /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047391 // alkylglycerophosphoethanolamine phosphodiesterase activity // inferred from electronic annotation 210840_s_at D29640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D29640.1 /DEF=Human mRNA for KIAA0051 gene, complete cds. /FEA=mRNA /GEN=KIAA0051 /DB_XREF=gi:473930 /UG=Hs.1742 IQ motif containing GTPase activating protein 1 /FL=gb:D29640.1 D29640 IQ motif containing GTPase activating protein 1 IQGAP1 8826 NM_003870 /// XM_005254984 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0035305 // negative regulation of dephosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005884 // actin filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 210841_s_at AF280546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280546.1 /DEF=Homo sapiens neuropilin-2 soluble isoform 9 (NRP2) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=NRP2 /PROD=neuropilin-2 soluble isoform 9 /DB_XREF=gi:11907929 /UG=Hs.17778 neuropilin 2 /FL=gb:AF280546.1 AF280546 neuropilin 2 NRP2 8828 NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934 0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210842_at AF280546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280546.1 /DEF=Homo sapiens neuropilin-2 soluble isoform 9 (NRP2) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=NRP2 /PROD=neuropilin-2 soluble isoform 9 /DB_XREF=gi:11907929 /UG=Hs.17778 neuropilin 2 /FL=gb:AF280546.1 AF280546 neuropilin 2 NRP2 8828 NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934 0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210843_s_at AF327560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF327560.1 /DEF=Homo sapiens protein kinase NYD-sp9 mRNA, complete cds. /FEA=mRNA /PROD=protein kinase NYD-sp9 /DB_XREF=gi:13195444 /UG=Hs.178121 KIAA0626 gene product /FL=gb:AF327560.1 AF327560 uncharacterized LOC101928198 /// microfibrillar-associated protein 3-like LOC101928198 /// MFAP3L 9848 /// 101928198 NM_001009554 /// NM_021647 /// XM_005263366 /// XM_005263368 /// XM_005263369 /// XM_005263370 /// XM_005263371 /// XM_006714423 /// XM_006714424 /// XM_006714425 /// XM_006714426 /// XM_006714427 /// XM_006714428 /// XR_244749 /// XR_249692 /// XR_251689 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210844_x_at D14705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D14705.1 /DEF=Human mRNA for alpha-catenin, complete cds. /FEA=mRNA /PROD=human alpha-catenin /DB_XREF=gi:415305 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:BC000385.1 gb:D14705.1 gb:D13866.1 D14705 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 210845_s_at U08839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U08839.1 /DEF=Human urokinase-type plasminogen activator receptor mRNA, complete cds. /FEA=mRNA /PROD=urokinase-type plasminogen activator receptor /DB_XREF=gi:517197 /UG=Hs.179657 plasminogen activator, urokinase receptor /FL=gb:U08839.1 U08839 plasminogen activator, urokinase receptor PLAUR 5329 NM_001005376 /// NM_001005377 /// NM_002659 /// XM_005258988 /// XM_005258989 /// XM_005258990 /// XM_006723241 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030162 // regulation of proteolysis // non-traceable author statement /// 0038195 // urokinase plasminogen activator signaling pathway // non-traceable author statement /// 0042730 // fibrinolysis // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030377 // urokinase plasminogen activator receptor activity // non-traceable author statement 210846_x_at AF220130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220130.1 /DEF=Homo sapiens tripartite motif protein TRIM14 alpha (TRIM14) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM14 /PROD=tripartite motif protein TRIM14 alpha /DB_XREF=gi:12407428 /UG=Hs.179703 KIAA0129 gene product /FL=gb:AF220130.1 AF220130 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210847_x_at AF026071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026071.1 /DEF=Homo sapiens soluble death receptor 3 beta (DR3) mRNA, complete cds. /FEA=mRNA /GEN=DR3 /PROD=soluble death receptor 3 beta /DB_XREF=gi:2570832 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) /FL=gb:AF026071.1 AF026071 tumor necrosis factor receptor superfamily, member 25 TNFRSF25 8718 NM_001039664 /// NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148974 0006915 // apoptotic process // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement 210848_at AF187554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF187554.1 /DEF=Homo sapiens sperm antigen-36 mRNA, complete cds. /FEA=mRNA /PROD=sperm antigen-36 /DB_XREF=gi:6653225 /UG=Hs.180532 glucose phosphate isomerase /FL=gb:AF187554.1 AF187554 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007599 // hemostasis // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0019242 // methylglyoxal biosynthetic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046185 // aldehyde catabolic process // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004347 // glucose-6-phosphate isomerase activity // inferred from electronic annotation /// 0004347 // glucose-6-phosphate isomerase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 210849_s_at AF135593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF135593.1 /DEF=Homo sapiens hVps41p (HVPS41) mRNA, alternative splice variant, complete cds. /FEA=mRNA /GEN=HVPS41 /PROD=hVps41p /DB_XREF=gi:12002285 /UG=Hs.180941 vacuolar protein sorting 41 (yeast homolog) /FL=gb:AF135593.1 AF135593 vacuolar protein sorting 41 homolog (S. cerevisiae) VPS41 27072 NM_014396 /// NM_080631 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030897 // HOPS complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210850_s_at AF000672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000672.1 /DEF=Homo sapiens ELK variant mRNA, complete cds. /FEA=mRNA /PROD=ELK variant /DB_XREF=gi:4100455 /UG=Hs.181128 ELK1, member of ETS oncogene family /FL=gb:AF000672.1 AF000672 ELK1, member of ETS oncogene family ELK1 2002 NM_001114123 /// NM_001257168 /// NM_005229 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210852_s_at AF229180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229180.1 /DEF=Homo sapiens alpha-aminoadipate semialdehyde synthase mRNA, complete cds. /FEA=mRNA /PROD=alpha-aminoadipate semialdehyde synthase /DB_XREF=gi:7264723 /UG=Hs.184168 lysine-ketoglutarate reductase saccharopine dehydrogenase /FL=gb:AF229180.1 AF229180 aminoadipate-semialdehyde synthase AASS 10157 NM_005763 /// XR_242220 /// XR_242221 0006554 // lysine catabolic process // non-traceable author statement /// 0006554 // lysine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019477 // L-lysine catabolic process // inferred from electronic annotation /// 0033512 // L-lysine catabolic process to acetyl-CoA via saccharopine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047130 // saccharopine dehydrogenase (NADP+, L-lysine-forming) activity // not recorded /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // not recorded /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // non-traceable author statement 210853_at AF150882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF150882.1 /DEF=Homo sapiens voltage-gated sodium channel alpha subunit, alternate splice variant SCN12A-s (SCN12A) mRNA, complete cds. /FEA=mRNA /GEN=SCN12A /PROD=voltage-gated sodium channel alpha subunit,alternate splice variant SCN12A-s /DB_XREF=gi:6693704 /UG=Hs.186877 sodium channel, voltage-gated, type XII, alpha polypeptide /FL=gb:AF150882.1 AF150882 sodium channel, voltage-gated, type XI, alpha subunit SCN11A 11280 NM_001287223 /// NM_014139 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0042493 // response to drug // traceable author statement /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0044299 // C-fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005272 // sodium channel activity // inferred from electronic annotation 210854_x_at U17986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17986.1 /DEF=Human GABAnoradrenaline transporter mRNA, complete cds. /FEA=mRNA /PROD=GABAnoradrenaline transporter /DB_XREF=gi:602433 /UG=Hs.187958 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 /FL=gb:U17986.1 U17986 solute carrier family 6 (neurotransmitter transporter), member 8 SLC6A8 6535 NM_001142805 /// NM_001142806 /// NM_005629 0006600 // creatine metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0015871 // choline transport // inferred from electronic annotation /// 0015881 // creatine transport // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // non-traceable author statement /// 1902598 // creatine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005308 // creatine transmembrane transporter activity // non-traceable author statement /// 0005309 // creatine:sodium symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 210855_at AF245390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF245390.1 /DEF=Homo sapiens GREB1c (GREB1) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=GREB1 /PROD=GREB1c /DB_XREF=gi:11611737 /UG=Hs.190846 Homo sapiens GREB1b (GREB1) mRNA, complete cds, alternatively spliced /FL=gb:AF245390.1 AF245390 growth regulation by estrogen in breast cancer 1 GREB1 9687 NM_014668 /// NM_033090 /// NM_148903 /// XM_005246192 /// XM_005246195 /// XM_005246196 /// XM_005246197 /// XM_006711904 /// XM_006711905 /// XM_006711906 /// XM_006711907 /// XM_006711908 /// XR_426961 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 210858_x_at U26455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U26455.1 /DEF=Human phosphatidylinositol 3-kinase homolog (ATM) mRNA, complete cds. /FEA=mRNA /GEN=ATM /PROD=phosphatidylinositol 3-kinase homolog /DB_XREF=gi:870785 /UG=Hs.194382 ataxia telangiectasia mutated (includes complementation groups A, C and D) /FL=gb:U26455.1 U26455 ATM serine/threonine kinase ATM 472 NM_000051 /// NM_138292 /// NM_138293 /// XM_005271561 /// XM_005271562 /// XM_005271564 /// XM_006718843 /// XM_006718844 /// XM_006718845 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0002331 // pre-B cell allelic exclusion // inferred from sequence or structural similarity /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007292 // female gamete generation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048599 // oocyte development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0072434 // signal transduction involved in mitotic G2 DNA damage checkpoint // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0035174 // histone serine kinase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 210859_x_at AF077973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077973.1 /DEF=Homo sapiens clone 36 CLN3 protein (CLN3) mRNA, complete cds. /FEA=mRNA /GEN=CLN3 /PROD=CLN3 protein /DB_XREF=gi:5801864 /UG=Hs.194660 ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) /FL=gb:AF077973.1 AF077973 ceroid-lipofuscinosis, neuronal 3 CLN3 1201 NM_000086 /// NM_001042432 /// NM_001286104 /// NM_001286105 /// NM_001286109 /// NM_001286110 0000046 // autophagic vacuole fusion // inferred from sequence or structural similarity /// 0001508 // action potential // inferred from sequence or structural similarity /// 0001575 // globoside metabolic process // inferred from mutant phenotype /// 0006457 // protein folding // traceable author statement /// 0006520 // cellular amino acid metabolic process // inferred from sequence or structural similarity /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006678 // glucosylceramide metabolic process // inferred from mutant phenotype /// 0006681 // galactosylceramide metabolic process // inferred from mutant phenotype /// 0006684 // sphingomyelin metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007034 // vacuolar transport // not recorded /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0015809 // arginine transport // inferred from direct assay /// 0016236 // macroautophagy // non-traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from sequence or structural similarity /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030163 // protein catabolic process // non-traceable author statement /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035752 // lysosomal lumen pH elevation // inferred from direct assay /// 0042133 // neurotransmitter metabolic process // inferred from sequence or structural similarity /// 0042987 // amyloid precursor protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 210861_s_at AF143679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF143679.1 /DEF=Homo sapiens lost in inflammatory breast cancer tumor suppressor protein (LIBC) mRNA, complete cds. /FEA=mRNA /GEN=LIBC /PROD=lost in inflammatory breast cancer tumorsuppressor protein /DB_XREF=gi:4877969 /UG=Hs.194678 WNT1 inducible signaling pathway protein 3 /FL=gb:AF143679.1 AF143679 WNT1 inducible signaling pathway protein 3 WISP3 8838 NM_003880 /// NM_130396 /// NM_198239 /// XM_005267195 /// XM_006715590 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 210862_s_at AF047190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047190.1 /DEF=Homo sapiens dimethylglycine dehydrogenase-like protein isoform 2 mRNA, complete cds. /FEA=mRNA /PROD=dimethylglycine dehydrogenase-like proteinisoform 2 /DB_XREF=gi:4235223 /UG=Hs.198003 sarcosine dehydrogenase /FL=gb:AF047190.1 gb:AJ223317.1 AF047190 sarcosine dehydrogenase SARDH 1757 NM_001134707 /// NM_007101 /// XM_005272170 /// XM_006716990 /// XM_006716991 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008480 // sarcosine dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 210864_x_at AF144240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF144240.1 /DEF=Homo sapiens hemochromatosis splice variant 1043-2283del,intron6ins mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant1043-2283del,intron6ins /DB_XREF=gi:11094320 /UG=Hs.20019 hemochromatosis /FL=gb:AF144240.1 AF144240 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 210865_at D38122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38122.1 /DEF=Human mRNA for Fas ligand, complete cds. /FEA=mRNA /PROD=Fas ligand /DB_XREF=gi:601892 /UG=Hs.2007 tumor necrosis factor (ligand) superfamily, member 6 /FL=gb:NM_000639.1 gb:U11821.1 gb:D38122.1 gb:U08137.1 D38122 Fas ligand (TNF superfamily, member 6) FASLG 356 NM_000639 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from genetic interaction /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0048388 // endosomal lumen acidification // inferred from electronic annotation /// 0070231 // T cell apoptotic process // inferred from direct assay /// 0070266 // necroptotic process // inferred from direct assay /// 0070848 // response to growth factor // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060205 // cytoplasmic membrane-bounded vesicle lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210866_s_at AF180475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180475.1 /DEF=Homo sapiens Not4-Np (NOT4-N) mRNA, complete cds. /FEA=mRNA /GEN=NOT4-N /PROD=Not4-Np /DB_XREF=gi:6856206 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:AF180475.1 AF180475 CCR4-NOT transcription complex, subunit 4 CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210867_at AF180475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180475.1 /DEF=Homo sapiens Not4-Np (NOT4-N) mRNA, complete cds. /FEA=mRNA /GEN=NOT4-N /PROD=Not4-Np /DB_XREF=gi:6856206 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:AF180475.1 AF180475 CCR4-NOT transcription complex, subunit 4 CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 210868_s_at BC001305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001305.1 /DEF=Homo sapiens, clone MGC:5487, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5487) /DB_XREF=gi:12654918 /UG=Hs.211556 hypothetical protein MGC5487 /FL=gb:BC001305.1 BC001305 ELOVL fatty acid elongase 6 ELOVL6 79071 NM_001130721 /// NM_024090 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030497 // fatty acid elongation // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042759 // long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 210869_s_at M29277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M29277.1 /DEF=Human isolate JuSo MUC18 glycoprotein mRNA (3 variant), complete cds. /FEA=mRNA /PROD=MUC18 glycoprotein /DB_XREF=gi:530047 /UG=Hs.211579 melanoma adhesion molecule /FL=gb:M29277.1 M29277 melanoma cell adhesion molecule /// microRNA 6756 MCAM /// MIR6756 4162 /// 102465453 NM_006500 /// NR_106814 /// XM_005271551 /// XM_005271552 /// XM_006718836 /// XM_006718837 /// XM_006718838 0003094 // glomerular filtration // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0061042 // vascular wound healing // inferred from expression pattern 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 210870_s_at BC005286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005286.1 /DEF=Homo sapiens, Similar to epilepsy, progressive myoclonus type 2, Lafora disease (laforin), clone MGC:12342, mRNA, complete cds. /FEA=mRNA /PROD=Similar to epilepsy, progressive myoclonus type2, Lafora disease (laforin) /DB_XREF=gi:13528989 /UG=Hs.22464 epilepsy, progressive myoclonus type 2, Lafora disease (laforin) /FL=gb:BC005286.1 BC005286 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) EPM2A 7957 NM_001018041 /// NM_005670 /// XM_006715564 /// XM_006715565 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // non-traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // not recorded /// 0046959 // habituation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019203 // carbohydrate phosphatase activity // not recorded /// 0019203 // carbohydrate phosphatase activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 2001070 // starch binding // inferred from electronic annotation 210871_x_at AL133046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL133046.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C0515 (from clone DKFZp434C0515); complete cds. /FEA=mRNA /GEN=DKFZp434C0515 /PROD=hypothetical protein /DB_XREF=gi:6453458 /UG=Hs.22587 KIAA0923 protein /FL=gb:AL133046.1 AL133046 synovial sarcoma, X breakpoint 2 interacting protein SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 210872_x_at BC001152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001152.1 /DEF=Homo sapiens, growth arrest-specific 7, clone MGC:1347, mRNA, complete cds. /FEA=mRNA /PROD=growth arrest-specific 7 /DB_XREF=gi:12654630 /UG=Hs.226133 growth arrest-specific 7 /FL=gb:BC001152.1 BC001152 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 210873_x_at U03891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U03891.2 /DEF=Homo sapiens phorbolin I mRNA, complete cds. /FEA=mRNA /PROD=phorbolin I /DB_XREF=gi:4895107 /UG=Hs.226307 phorbolin (similar to apolipoprotein B mRNA editing protein) /FL=gb:U03891.2 U03891 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A /// APOBEC3A and APOBEC3B deletion hybrid APOBEC3A /// APOBEC3A_B 200315 /// 100913187 NM_001193289 /// NM_001270406 /// NM_145699 /// XM_005276959 /// XM_005276960 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0009972 // cytidine deamination // inferred from direct assay /// 0009972 // cytidine deamination // inferred from mutant phenotype /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0044356 // clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from mutant phenotype /// 0071466 // cellular response to xenobiotic stimulus // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0004126 // cytidine deaminase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from mutant phenotype 210874_s_at BC004483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004483.1 /DEF=Homo sapiens, putative tumor suppressor, clone MGC:10586, mRNA, complete cds. /FEA=mRNA /PROD=putative tumor suppressor /DB_XREF=gi:13325345 /UG=Hs.22919 putative tumor suppressor /FL=gb:BC004483.1 BC004483 N-acetyltransferase 6 (GCN5-related) NAT6 24142 NM_001200016 /// NM_001200018 /// NM_012191 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from expression pattern /// 0051216 // cartilage development // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071493 // cellular response to UV-B // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0033906 // hyaluronoglucuronidase activity // inferred from direct assay 210875_s_at U12170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U12170.1 /DEF=Human zinc finger homeodomain protein mRNA, complete cds. /FEA=mRNA /PROD=zinc finger homeodomain protein /DB_XREF=gi:529172 /UG=Hs.232068 transcription factor 8 (represses interleukin 2 expression) /FL=gb:U12170.1 U12170 uncharacterized LOC100996668 /// zinc finger E-box binding homeobox 1 LOC100996668 /// ZEB1 6935 /// 100996668 NM_001128128 /// NM_001174093 /// NM_001174094 /// NM_001174095 /// NM_001174096 /// NM_030751 /// NR_024285 /// NR_024286 /// NR_024287 /// XM_005252575 /// XM_005252576 /// XM_006717497 /// XM_006717498 /// XM_006717499 /// XR_158862 /// XR_159196 /// XR_171848 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010464 // regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 210876_at M62896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M62896.1 /DEF=Human lipocortin (LIP) 2 pseudogene mRNA, complete cds-like region. /FEA=mRNA /DB_XREF=gi:187146 /UG=Hs.234757 Human lipocortin (LIP) 2 pseudogene mRNA, complete cds-like region /FL=gb:M62896.1 M62896 annexin A2 pseudogene 1 ANXA2P1 303 NR_001562 0001525 // angiogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 210878_s_at BC001202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001202.1 /DEF=Homo sapiens, clone MGC:3185, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3185) /DB_XREF=gi:12654720 /UG=Hs.24125 putative zinc finger protein /FL=gb:BC001202.1 BC001202 lysine (K)-specific demethylase 3B KDM3B 51780 NM_016604 /// XM_005272018 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 210879_s_at AF334812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF334812.1 /DEF=Homo sapiens Rab11 interacting protein Rip11a mRNA, complete cds. /FEA=mRNA /PROD=Rab11 interacting protein Rip11a /DB_XREF=gi:13377896 /UG=Hs.24557 KIAA0857 protein /FL=gb:AF334812.1 AF334812 RAB11 family interacting protein 5 (class I) RAB11FIP5 26056 NM_015470 /// XM_005264251 /// XM_005264252 /// XM_005264253 /// XM_006711985 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0071468 // cellular response to acidity // inferred from direct assay /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from direct assay 210880_s_at AB001467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB001467.1 /DEF=Homo sapiens mRNA for Efs2, complete cds. /FEA=mRNA /PROD=Efs2 /DB_XREF=gi:2829303 /UG=Hs.24587 signal transduction protein (SH3 containing) /FL=gb:AB001467.1 AB001467 embryonal Fyn-associated substrate EFS 10278 NM_001277174 /// NM_005864 /// NM_032459 /// XM_005267256 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 210881_s_at M17863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M17863.1 /DEF=Human preproinsulin-like growth factor II (IGF-II) variant mRNA, complete cds. /FEA=mRNA /GEN=IGF2 /DB_XREF=gi:182527 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:M17862.1 gb:M17863.1 gb:M29645.1 M17863 insulin-like growth factor 2 (somatomedin A) /// INS-IGF2 readthrough IGF2 /// INS-IGF2 3481 /// 723961 NM_000612 /// NM_001007139 /// NM_001042376 /// NM_001127598 /// NM_001291861 /// NM_001291862 /// NR_003512 0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 210882_s_at U04811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04811.1 /DEF=Human trophinin mRNA, complete cds. /FEA=mRNA /PROD=trophinin /DB_XREF=gi:905357 /UG=Hs.259802 trophinin /FL=gb:U04811.1 U04811 trophinin TRO 7216 NM_001039705 /// NM_001271183 /// NM_001271184 /// NM_016157 /// NM_177556 /// NM_177557 /// NR_073148 /// NR_073149 /// XM_006724599 /// XM_006724600 /// XM_006724601 /// XM_006724602 /// XM_006724603 /// XM_006724604 /// XM_006724605 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 210883_x_at U57001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U57001.1 /DEF=Human ligand for eph-related receptor tyrosine kinases (EPLG8) mRNA, complete cds. /FEA=mRNA /GEN=EPLG8 /PROD=ligand for eph-related receptor tyrosinekinases /DB_XREF=gi:1469781 /UG=Hs.26988 ephrin-B3 /FL=gb:U57001.1 U57001 ephrin-B3 EFNB3 1949 NM_001406 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // not recorded /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016198 // axon choice point recognition // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0046875 // ephrin receptor binding // inferred from direct assay 210884_s_at AF168619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF168619.1 /DEF=Homo sapiens HE2 gamma1 mRNA, complete cds. /FEA=mRNA /PROD=HE2 gamma1 /DB_XREF=gi:7140929 /UG=Hs.2717 sperm associated antigen 11 /FL=gb:AF168619.1 AF168619 sperm associated antigen 11A SPAG11A 653423 NM_001081552 /// XM_005272391 /// XM_005272392 /// XM_005272393 0006952 // defense response // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 210885_s_at AF220133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220133.1 /DEF=Homo sapiens tripartite motif protein TRIM15 beta (TRIM15) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM15 /PROD=tripartite motif protein TRIM15 beta /DB_XREF=gi:12407434 /UG=Hs.274295 ring finger protein 9 /FL=gb:AF220133.1 AF220133 tripartite motif containing 15 TRIM15 89870 NM_033229 /// NM_052812 /// XM_005249471 /// XM_005272907 /// XM_005274898 /// XM_005275063 /// XM_005275195 /// XM_005275319 /// XM_005275490 /// XM_005275628 0007500 // mesodermal cell fate determination // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype /// 1901253 // negative regulation of intracellular transport of viral material // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210886_x_at AB007457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB007457.1 /DEF=Homo sapiens mRNA for P53TG1-C, complete cds. /FEA=mRNA /GEN=P53TG1 /PROD=P53TG1-C /DB_XREF=gi:5006270 /UG=Hs.274329 TP53 target gene 1 /FL=gb:AB007457.1 AB007457 TP53 target 1 (non-protein coding) TP53TG1 11257 NM_007233 /// NR_015381 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement 210887_s_at AF216185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF216185.1 /DEF=Homo sapiens tissue-type brain Ellis-van Creveld syndrome protein (EVC) mRNA, complete cds. /FEA=mRNA /GEN=EVC /PROD=Ellis-van Creveld syndrome protein /DB_XREF=gi:7141126 /UG=Hs.274446 Ellis van Creveld syndrome /FL=gb:AF216185.1 AF216185 Ellis van Creveld syndrome EVC 2121 NM_014556 /// NM_153717 /// XM_005247952 /// XM_006713865 /// XM_006713866 /// XM_006713867 /// XR_427471 /// XR_427472 /// XR_427473 /// XR_427474 /// XR_427475 /// XR_427476 /// XR_427477 0001501 // skeletal system development // traceable author statement /// 0003416 // endochondral bone growth // inferred from sequence or structural similarity /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 210888_s_at AF116713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116713.1 /DEF=Homo sapiens PRO2769 mRNA, complete cds. /FEA=mRNA /PROD=PRO2769 /DB_XREF=gi:7959924 /UG=Hs.2777 inter-alpha (globulin) inhibitor, H1 polypeptide /FL=gb:AF116713.1 AF116713 inter-alpha-trypsin inhibitor heavy chain 1 ITIH1 3697 NM_001166434 /// NM_001166435 /// NM_001166436 /// NM_002215 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0045321 // leukocyte activation // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 210889_s_at M31933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31933.1 /DEF=Human IgG low affinity Fc fragment receptor (FcRIIb3) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:182598 /UG=Hs.278443 Fc fragment of IgG, low affinity IIb, receptor for (CD32) /FL=gb:M31933.1 M31933 Fc fragment of IgG, low affinity IIb, receptor (CD32) FCGR2B 2213 NM_001002273 /// NM_001002274 /// NM_001002275 /// NM_001190828 /// NM_004001 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from electronic annotation 210890_x_at U24078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24078.1 /DEF=Human p58 natural killer cell receptor precursor mRNA, clone 47.11, complete cds. /FEA=mRNA /PROD=p58 natural killer cell receptor precursor /DB_XREF=gi:897908 /UG=Hs.278453 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 /FL=gb:AF285431.1 gb:NM_014218.1 gb:L41267.1 gb:U24076.1 gb:U24078.1 U24078 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 KIR2DL1 3802 NM_014218 /// XM_005258889 /// XM_005277253 /// XM_005278262 /// XM_006725421 /// XM_006725425 /// XM_006725428 /// XM_006725430 /// XM_006725437 /// XM_006725438 /// XM_006725442 /// XM_006725655 /// XM_006725656 /// XM_006725661 /// XM_006725662 /// XM_006725663 /// XM_006725664 /// XM_006725668 /// XM_006725788 /// XM_006725791 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 210891_s_at AF035737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF035737.1 /DEF=Homo sapiens general transcription factor 2-I (GTF2I) mRNA, complete cds. /FEA=mRNA /GEN=GTF2I /PROD=general transcription factor 2-I; alternativesplice product /DB_XREF=gi:2827179 /UG=Hs.278589 general transcription factor II, i /FL=gb:AF035737.1 AF035737 general transcription factor IIi /// general transcription factor IIi, pseudogene 1 /// general transcription factor II, i, pseudogene GTF2I /// GTF2IP1 /// LOC100093631 2969 /// 2970 /// 100093631 NM_001163636 /// NM_001280800 /// NM_001518 /// NM_032999 /// NM_033000 /// NM_033001 /// NR_002206 /// NR_003580 /// XM_005250291 /// XM_005250296 /// XM_006715939 /// XM_006715940 /// XM_006715941 /// XM_006715942 /// XM_006715943 /// XM_006715944 /// XM_006715945 /// XM_006715946 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 210892_s_at BC004472 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004472.1 /DEF=Homo sapiens, Similar to general transcription factor II, i, clone MGC:10428, mRNA, complete cds. /FEA=mRNA /PROD=Similar to general transcription factor II, i /DB_XREF=gi:13325321 /UG=Hs.278589 general transcription factor II, i /FL=gb:BC004472.1 BC004472 general transcription factor IIi GTF2I 2969 NM_001163636 /// NM_001280800 /// NM_001518 /// NM_032999 /// NM_033000 /// NM_033001 /// XM_005250291 /// XM_005250296 /// XM_006715939 /// XM_006715940 /// XM_006715941 /// XM_006715942 /// XM_006715943 /// XM_006715944 /// XM_006715945 /// XM_006715946 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 210893_at AF118064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118064.1 /DEF=Homo sapiens PRO1510 mRNA, complete cds. /FEA=mRNA /PROD=PRO1510 /DB_XREF=gi:6650773 /UG=Hs.278920 PRO1510 protein /FL=gb:AF118064.1 AF118064 210894_s_at BC001433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001433.1 /DEF=Homo sapiens, Similar to centrosomal protein 2, clone MGC:1218, mRNA, complete cds. /FEA=mRNA /PROD=Similar to centrosomal protein 2 /DB_XREF=gi:12655156 /UG=Hs.27910 centrosomal protein 2 /FL=gb:BC001433.1 BC001433 centrosomal protein 250kDa CEP250 11190 NM_001035518 /// NM_007186 /// XM_005260262 /// XM_005260263 /// XM_005260264 /// XM_005260265 /// XM_006723690 /// XM_006723691 /// XM_006723692 /// XM_006723693 /// XM_006723694 /// XM_006723695 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0030997 // regulation of centriole-centriole cohesion // inferred from direct assay /// 0033365 // protein localization to organelle // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 210895_s_at L25259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L25259.1 /DEF=Human CTLA4 counter-receptor (B7-2) mRNA, complete cds. /FEA=mRNA /GEN=B7-2 /PROD=CTLA4 counter-receptor /DB_XREF=gi:416368 /UG=Hs.27954 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) /FL=gb:L25259.1 L25259 CD86 molecule CD86 942 NM_001206924 /// NM_001206925 /// NM_006889 /// NM_175862 /// NM_176892 /// XM_005247905 0001878 // response to yeast // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002668 // negative regulation of T cell anergy // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042110 // T cell activation // inferred by curator /// 0042113 // B cell activation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043017 // positive regulation of lymphotoxin A biosynthetic process // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045404 // positive regulation of interleukin-4 biosynthetic process // non-traceable author statement /// 0045630 // positive regulation of T-helper 2 cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement 210896_s_at AF306765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF306765.1 /DEF=Homo sapiens junctate mRNA, complete cds. /FEA=mRNA /PROD=junctate /DB_XREF=gi:11991236 /UG=Hs.283664 aspartate beta-hydroxylase /FL=gb:AF306765.1 AF306765 aspartate beta-hydroxylase ASPH 444 NM_001164750 /// NM_001164751 /// NM_001164752 /// NM_001164753 /// NM_001164754 /// NM_001164755 /// NM_001164756 /// NM_004318 /// NM_020164 /// NM_032466 /// NM_032467 /// NM_032468 /// XM_005251235 /// XM_005251236 /// XM_005251238 /// XM_005251239 /// XM_005251240 /// XM_005251241 /// XM_005251242 /// XM_005251243 /// XM_005251244 /// XM_005251246 /// XM_005251247 /// XM_005251248 /// XM_005251249 /// XM_005251250 /// XM_006716448 /// XM_006716449 0005513 // detection of calcium ion // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0018193 // peptidyl-amino acid modification // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0033198 // response to ATP // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1901879 // regulation of protein depolymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement /// 0034704 // calcium channel complex // traceable author statement 0004597 // peptide-aspartate beta-dioxygenase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044325 // ion channel binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 210904_s_at U81380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U81380.2 /DEF=Human interleukin-13 receptor soluble form mRNA, complete cds. /FEA=mRNA /PROD=interleukin-13 receptor soluble form /DB_XREF=gi:5174767 /UG=Hs.285115 interleukin 13 receptor, alpha 1 /FL=gb:U81380.2 U81380 interleukin 13 receptor, alpha 1 IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 210905_x_at AF268613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF268613.1 /DEF=Homo sapiens POU 5 domain protein (POU5FLC1) mRNA, complete cds. /FEA=mRNA /GEN=POU5FLC1 /PROD=POU 5 domain protein /DB_XREF=gi:12382245 /UG=Hs.2860 POU domain, class 5, transcription factor 1 /FL=gb:AF268613.1 AF268613 POU class 5 homeobox 1 pseudogene 4 POU5F1P4 645682 NR_034180 0001714 // endodermal cell fate specification // inferred from direct assay /// 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0003130 // BMP signaling pathway involved in heart induction // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009786 // regulation of asymmetric cell division // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from direct assay /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060795 // cell fate commitment involved in formation of primary germ layer // inferred from mutant phenotype /// 0060913 // cardiac cell fate determination // inferred from direct assay /// 0060965 // negative regulation of gene silencing by miRNA // inferred from mutant phenotype /// 0090081 // regulation of heart induction by regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090308 // regulation of methylation-dependent chromatin silencing // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 210906_x_at U34846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34846.1 /DEF=Human mercurial-insensitive water channel mRNA, form 2, complete cds. /FEA=mRNA /PROD=mercurial-insensitive water channel /DB_XREF=gi:1072054 /UG=Hs.288650 aquaporin 4 /FL=gb:U34846.1 U34846 aquaporin 4 AQP4 361 NM_001650 /// NM_004028 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // not recorded /// 0015288 // porin activity // inferred from electronic annotation 210907_s_at BC002506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002506.1 /DEF=Homo sapiens, programmed cell death 10, clone MGC:1212, mRNA, complete cds. /FEA=mRNA /PROD=programmed cell death 10 /DB_XREF=gi:12803370 /UG=Hs.28866 programmed cell death 10 /FL=gb:BC002506.1 BC002506 programmed cell death 10 PDCD10 11235 NM_007217 /// NM_145859 /// NM_145860 /// XM_005247086 /// XM_005247087 /// XM_005247088 /// XM_006713485 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 210908_s_at AB055804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB055804.1 /DEF=Homo sapiens mRNA for MM-1 beta, complete cds. /FEA=mRNA /GEN=mm-1 /PROD=MM-1 beta /DB_XREF=gi:12957174 /UG=Hs.288856 prefoldin 5 /FL=gb:AB055804.1 AB055804 prefoldin subunit 5 PFDN5 5204 NM_002624 /// NM_145896 /// NM_145897 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0016272 // prefoldin complex // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 210909_x_at U19518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19518.1 /DEF=Human (apoargC) short mRNA, complete cds. /FEA=mRNA /GEN=apoargC /DB_XREF=gi:642945 /UG=Hs.289049 apolipoprotein (a) related gene C /FL=gb:U19518.1 U19518 lipoprotein, Lp(a)-like 2, pseudogene LPAL2 80350 NM_024492 /// NM_145727 /// NR_028092 /// NR_028093 0005576 // extracellular region // inferred from electronic annotation 210910_s_at BC000487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000487.1 /DEF=Homo sapiens, Similar to POM (POM121 rat homolog) and ZP3 fusion protein, clone MGC:8359, mRNA, complete cds. /FEA=mRNA /PROD=Similar to POM (POM121 rat homolog) and ZP3fusion protein /DB_XREF=gi:12653432 /UG=Hs.296380 POM (POM121 rat homolog) and ZP3 fusion protein /FL=gb:BC000487.1 BC000487 POM121 and ZP3 fusion POMZP3 22932 NM_012230 /// NM_152992 210911_at M96843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M96843.1 /DEF=Human striated muscle contraction regulatory protein (Id2B) mRNA, complete cds. /FEA=mRNA /GEN=Id2B /PROD=contractile protein /DB_XREF=gi:397775 /UG=Hs.296811 Human striated muscle contraction regulatory protein (Id2B) mRNA, complete cds /FL=gb:M96843.1 M96843 inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) ID2B 84099 NM_001039082 /// NR_026582 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 210912_x_at M99422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M99422.1 /DEF=Homo sapiens glutathione transferase (GST) mRNA, complete cds. /FEA=mRNA /GEN=GST /PROD=glutathione transferase /DB_XREF=gi:183662 /UG=Hs.301961 glutathione S-transferase M4 /FL=gb:M99422.1 M99422 glutathione S-transferase mu 4 GSTM4 2948 NM_000850 /// NM_147148 /// NM_147149 /// NR_024538 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 210913_at AF217289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF217289.1 /DEF=Homo sapiens cadherin 20 (CDH20) mRNA, complete cds. /FEA=mRNA /GEN=CDH20 /PROD=cadherin 20 /DB_XREF=gi:10834606 /UG=Hs.302138 Homo sapiens cadherin 20 (CDH20) mRNA, complete cds /FL=gb:AF217289.1 AF217289 cadherin 20, type 2 CDH20 28316 NM_031891 /// XM_005266682 /// XM_005266684 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210914_at AF130071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130071.1 /DEF=Homo sapiens clone FLB9023 PRO2425 mRNA, complete cds. /FEA=mRNA /PROD=PRO2425 /DB_XREF=gi:11493448 /UG=Hs.302148 Homo sapiens clone FLB9023 PRO2425 mRNA, complete cds /FL=gb:AF130071.1 AF130071 210915_x_at M15564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15564.1 /DEF=Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, complete cds. /FEA=mRNA /GEN=TCRB /DB_XREF=gi:339011 /UG=Hs.303157 T cell receptor beta locus /FL=gb:M15564.1 M15564 T cell receptor beta constant 1 TRBC1 28639 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0043382 // positive regulation of memory T cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from electronic annotation /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0045519 // interleukin-23 receptor binding // inferred from direct assay /// 0045519 // interleukin-23 receptor binding // inferred from electronic annotation 210916_s_at AF098641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF098641.1 /DEF=Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds. /FEA=mRNA /GEN=CD44 /PROD=CD44 isoform RC /DB_XREF=gi:3832517 /UG=Hs.306278 Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds /FL=gb:AF098641.1 AF098641 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 210917_at AF119914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119914.1 /DEF=Homo sapiens PRO3078 mRNA, complete cds. /FEA=mRNA /PROD=PRO3078 /DB_XREF=gi:7770264 /UG=Hs.306573 Homo sapiens PRO3078 mRNA, complete cds /FL=gb:AF119914.1 AF119914 YES proto-oncogene 1, Src family tyrosine kinase YES1 7525 NM_005433 /// XM_005258139 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction 210918_at AF130075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130075.1 /DEF=Homo sapiens clone FLB9413 PRO2532 mRNA, complete cds. /FEA=mRNA /PROD=PRO2532 /DB_XREF=gi:11493455 /UG=Hs.306961 Homo sapiens clone FLB9413 PRO2532 mRNA, complete cds /FL=gb:AF130075.1 AF130075 210919_at AF130097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130097.1 /DEF=Homo sapiens clone FLC0964 PRO2946 mRNA, complete cds. /FEA=mRNA /PROD=PRO2946 /DB_XREF=gi:11493497 /UG=Hs.306963 Homo sapiens clone FLC0964 PRO2946 mRNA, complete cds /FL=gb:AF130097.1 AF130097 PH domain and leucine rich repeat protein phosphatase 1 PHLPP1 23239 NM_194449 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210920_x_at BC003528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003528.1 /DEF=Homo sapiens, clone MGC:10782, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10782) /DB_XREF=gi:13097626 /UG=Hs.306969 Homo sapiens, clone MGC:10782, mRNA, complete cds /FL=gb:BC003528.1 BC003528 210921_at BC002821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002821.1 /DEF=Homo sapiens, clone MGC:3518, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3518) /DB_XREF=gi:12803948 /UG=Hs.306987 Homo sapiens, clone MGC:3518, mRNA, complete cds /FL=gb:BC002821.1 BC002821 myb-related transcription factor, partner of profilin-like LOC101929078 101929078 XM_005257911 /// XM_005276629 210922_at BC000772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000772.1 /DEF=Homo sapiens, Similar to KIAA0377 gene product, clone MGC:3268, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0377 gene product /DB_XREF=gi:12653956 /UG=Hs.307000 Homo sapiens, Similar to KIAA0377 gene product, clone MGC:3268, mRNA, complete cds /FL=gb:BC000772.1 BC000772 CTB-102L5.7 210923_at BC000651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000651.1 /DEF=Homo sapiens, Similar to solute carrier family 1 (glutamate transporter), member 7, clone MGC:2078, mRNA, complete cds. /FEA=mRNA /PROD=Similar to solute carrier family 1 (glutamatetransporter), member 7 /DB_XREF=gi:12653730 /UG=Hs.307039 Homo sapiens, Similar to solute carrier family 1 (glutamate transporter), member 7, clone MGC:2078, mRNA, complete cds /FL=gb:BC000651.1 BC000651 solute carrier family 1 (glutamate transporter), member 7 SLC1A7 6512 NM_001287595 /// NM_001287596 /// NM_001287597 /// NM_006671 /// NR_109858 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0015813 // L-glutamate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 210924_at BC000189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000189.1 /DEF=Homo sapiens, Similar to neuroblastoma (nerve tissue) protein, clone MGC:1342, mRNA, complete cds. /FEA=mRNA /PROD=Similar to neuroblastoma (nerve tissue) protein /DB_XREF=gi:12652868 /UG=Hs.307042 Homo sapiens, Similar to neuroblastoma (nerve tissue) protein, clone MGC:1342, mRNA, complete cds /FL=gb:BC000189.1 BC000189 olfactomedin 1 OLFM1 10439 NM_001282611 /// NM_001282612 /// NM_006334 /// NM_014279 /// NM_058199 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 210925_at U18288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18288.1 /DEF=Human clone CIITA-10 MHC class II transactivator CIITA mRNA, complete cds. /FEA=mRNA /PROD=MHC class II transactivator CIITA /DB_XREF=gi:836910 /UG=Hs.3076 MHC class II transactivator /FL=gb:U18288.1 U18288 class II, major histocompatibility complex, transactivator CIITA 4261 NM_000246 /// NM_001286402 /// NM_001286403 /// NR_104444 /// XM_005255320 /// XM_005255321 /// XM_005255323 /// XM_006720880 /// XM_006720881 /// XM_006720882 /// XM_006720883 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032966 // negative regulation of collagen biosynthetic process // inferred by curator /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0045345 // positive regulation of MHC class I biosynthetic process // inferred from direct assay /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 210926_at AY014272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY014272.1 /DEF=Homo sapiens FKSG30 (FKSG30) mRNA, complete cds. /FEA=mRNA /GEN=FKSG30 /PROD=FKSG30 /DB_XREF=gi:12408251 /UG=Hs.315492 Homo sapiens FKSG30 (FKSG30) mRNA, complete cds /FL=gb:AY014272.1 AY014272 POTE ankyrin domain family, member K, pseudogene POTEKP 440915 NM_001017421 /// NR_033885 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 210927_x_at BC004239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004239.1 /DEF=Homo sapiens, jumping translocation breakpoint, clone MGC:10274, mRNA, complete cds. /FEA=mRNA /PROD=jumping translocation breakpoint /DB_XREF=gi:13278986 /UG=Hs.323093 Homo sapiens, jumping translocation breakpoint, clone MGC:10274, mRNA, complete cds /FL=gb:BC004239.1 BC004239 jumping translocation breakpoint JTB 10899 NM_006694 0000910 // cytokinesis // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0019901 // protein kinase binding // inferred from direct assay 210928_at AF130057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130057.1 /DEF=Homo sapiens clone FLB5539 PRO1454 mRNA, complete cds. /FEA=mRNA /PROD=PRO1454 /DB_XREF=gi:11493420 /UG=Hs.323288 Homo sapiens clone FLB5539 PRO1454 mRNA, complete cds /FL=gb:AF130057.1 AF130057 210929_s_at AF130057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130057.1 /DEF=Homo sapiens clone FLB5539 PRO1454 mRNA, complete cds. /FEA=mRNA /PROD=PRO1454 /DB_XREF=gi:11493420 /UG=Hs.323288 Homo sapiens clone FLB5539 PRO1454 mRNA, complete cds /FL=gb:AF130057.1 AF130057 alpha-2-HS-glycoprotein AHSG 197 NM_001622 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006907 // pinocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // non-traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype /// 0050766 // positive regulation of phagocytosis // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0019210 // kinase inhibitor activity // non-traceable author statement 210930_s_at AF177761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF177761.2 /DEF=Homo sapiens herstatin (HER-2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=HER-2 /PROD=herstatin /DB_XREF=gi:10181232 /UG=Hs.323910 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuroglioblastoma derived oncogene homolog) /FL=gb:AF177761.2 AF177761 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 ERBB2 2064 NM_001005862 /// NM_001289936 /// NM_001289937 /// NM_001289938 /// NM_004448 /// NR_110535 /// XM_005257140 /// XM_006721765 /// XM_006721766 /// XM_006721767 /// XM_006721768 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from genetic interaction /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030879 // mammary gland development // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from direct assay /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from direct assay /// 0042552 // myelination // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045765 // regulation of angiogenesis // non-traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from mutant phenotype /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043235 // receptor complex // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001042 // RNA polymerase I core binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from genetic interaction /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043125 // ErbB-3 class receptor binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // non-traceable author statement 210931_at AF293342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF293342.1 /DEF=Homo sapiens RNF6 protein (RNF6) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=RNF6 /PROD=RNF6 protein /DB_XREF=gi:12656362 /UG=Hs.32597 ring finger protein (C3H2C3 type) 6 /FL=gb:AF293342.1 AF293342 ring finger protein (C3H2C3 type) 6 RNF6 6049 NM_005977 /// NM_183043 /// NM_183044 /// NM_183045 /// XM_005266485 /// XM_005266486 /// XM_006719854 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from sequence or structural similarity /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 210932_s_at AF293342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF293342.1 /DEF=Homo sapiens RNF6 protein (RNF6) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=RNF6 /PROD=RNF6 protein /DB_XREF=gi:12656362 /UG=Hs.32597 ring finger protein (C3H2C3 type) 6 /FL=gb:AF293342.1 AF293342 ring finger protein (C3H2C3 type) 6 RNF6 6049 NM_005977 /// NM_183043 /// NM_183044 /// NM_183045 /// XM_005266485 /// XM_005266486 /// XM_006719854 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from sequence or structural similarity /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 210933_s_at BC004908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004908.1 /DEF=Homo sapiens, clone MGC:4655, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4655) /DB_XREF=gi:13436196 /UG=Hs.326737 Homo sapiens, clone MGC:4655, mRNA, complete cds /FL=gb:BC004908.1 BC004908 fascin actin-bundling protein 1 FSCN1 6624 NM_003088 0008283 // cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0048870 // cell motility // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071437 // invadopodium // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 210934_at BC004473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004473.1 /DEF=Homo sapiens, clone MGC:10442, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10442) /DB_XREF=gi:13325324 /UG=Hs.326772 Homo sapiens, clone MGC:10442, mRNA, complete cds /FL=gb:BC004473.1 BC004473 BLK proto-oncogene, Src family tyrosine kinase BLK 640 NM_001715 /// XM_005272390 /// XM_006716250 /// XM_006716251 /// XM_006716252 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210935_s_at AF274954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274954.1 /DEF=Homo sapiens PNAS-29 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-29 /DB_XREF=gi:12751070 /UG=Hs.326791 Homo sapiens PNAS-29 mRNA, complete cds /FL=gb:AF274954.1 AF274954 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210936_at AF274954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274954.1 /DEF=Homo sapiens PNAS-29 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-29 /DB_XREF=gi:12751070 /UG=Hs.326791 Homo sapiens PNAS-29 mRNA, complete cds /FL=gb:AF274954.1 AF274954 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 210937_s_at U35632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35632.1 /DEF=Human insulin promoter factor 1 (PDX-1) mRNA, complete cds. /FEA=mRNA /GEN=PDX-1 /PROD=insulin promoter factor 1 /DB_XREF=gi:1197837 /UG=Hs.32938 insulin promoter factor 1, homeodomain transcription factor /FL=gb:U35632.1 gb:NM_000209.1 gb:U30329.1 U35632 pancreatic and duodenal homeobox 1 PDX1 3651 NM_000209 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003309 // type B pancreatic cell differentiation // inferred from direct assay /// 0003309 // type B pancreatic cell differentiation // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010040 // response to iron(II) ion // inferred from electronic annotation /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010260 // organ senescence // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033273 // response to vitamin // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051594 // detection of glucose // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210938_at U30329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U30329.1 /DEF=Human insulin promoter factor 1 (IPF1) mRNA, complete cds. /FEA=mRNA /GEN=IPF1 /PROD=insulin promoter factor 1 /DB_XREF=gi:929922 /UG=Hs.32938 insulin promoter factor 1, homeodomain transcription factor /FL=gb:U35632.1 gb:NM_000209.1 gb:U30329.1 U30329 pancreatic and duodenal homeobox 1 PDX1 3651 NM_000209 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003309 // type B pancreatic cell differentiation // inferred from direct assay /// 0003309 // type B pancreatic cell differentiation // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010040 // response to iron(II) ion // inferred from electronic annotation /// 0010157 // response to chlorate // inferred from electronic annotation /// 0010260 // organ senescence // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033273 // response to vitamin // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051594 // detection of glucose // inferred from sequence or structural similarity /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210939_s_at L76631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76631.1 /DEF=Homo sapiens metabotropic glutamate receptor 1 beta (mGluR1beta) mRNA, complete cds. /FEA=mRNA /GEN=mGluR1 /PROD=metabotropic glutamate receptor /DB_XREF=gi:1477389 /UG=Hs.32945 glutamate receptor, metabotropic 1 /FL=gb:L76631.1 gb:U31216.1 L76631 glutamate receptor, metabotropic 1 GRM1 2911 NM_000838 /// NM_001114329 /// NM_001278064 /// NM_001278065 /// NM_001278066 /// NM_001278067 /// XM_006715467 /// XM_006715468 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // not recorded /// 0007216 // G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0038042 // dimeric G-protein coupled receptor signaling pathway // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from mutant phenotype /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from direct assay /// 0038038 // G-protein coupled receptor homodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0008066 // glutamate receptor activity // traceable author statement 210940_s_at U31216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31216.1 /DEF=Human metabotropic glutamate receptor 1 beta (mGluR1beta) mRNA, complete cds. /FEA=mRNA /GEN=mGluR1beta /PROD=metabotropic glutamate receptor 1 beta /DB_XREF=gi:945098 /UG=Hs.32945 glutamate receptor, metabotropic 1 /FL=gb:L76631.1 gb:U31216.1 U31216 glutamate receptor, metabotropic 1 GRM1 2911 NM_000838 /// NM_001114329 /// NM_001278064 /// NM_001278065 /// NM_001278066 /// NM_001278067 /// XM_006715467 /// XM_006715468 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // not recorded /// 0007216 // G-protein coupled glutamate receptor signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0038042 // dimeric G-protein coupled receptor signaling pathway // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from mutant phenotype /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from direct assay /// 0038038 // G-protein coupled receptor homodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0008066 // glutamate receptor activity // traceable author statement 210941_at AB006756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006756.1 /DEF=Homo sapiens mRNA for PCDH7 (BH-Pcdh)b, complete cds. /FEA=mRNA /PROD=PCDH7 (BH-Pcdh)b /DB_XREF=gi:2979419 /UG=Hs.34073 BH-protocadherin (brain-heart) /FL=gb:AB006756.1 AB006756 protocadherin 7 PCDH7 5099 NM_001173523 /// NM_002589 /// NM_032456 /// NM_032457 /// XM_005248163 /// XM_005248164 /// XM_005248165 /// XM_005248166 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 210942_s_at AB022918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB022918.1 /DEF=Homo sapiens mRNA for alpha2,3-sialyltransferase ST3Gal VI, complete cds. /FEA=mRNA /GEN=ST3Gal VI /PROD=alpha2,3-sialyltransferase ST3Gal VI /DB_XREF=gi:4827246 /UG=Hs.34578 alpha2,3-sialyltransferase /FL=gb:AB022918.1 AB022918 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 ST3GAL6 10402 NM_001271142 /// NM_001271145 /// NM_001271146 /// NM_001271147 /// NM_001271148 /// NM_006100 /// XM_005247067 /// XM_005247068 /// XM_005247069 /// XM_005247070 /// XM_005247071 /// XM_005247072 /// XM_006713474 /// XM_006713475 /// XM_006713476 /// XR_427357 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052798 // beta-galactoside alpha-2,3-sialyltransferase activity // inferred from direct assay 210943_s_at U84744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84744.1 /DEF=Human Chediak-Higashi syndrome protein short isoform (LYST) mRNA, complete cds. /FEA=mRNA /GEN=LYST /PROD=Chediak-Higashi syndrome protein short isoform /DB_XREF=gi:2654473 /UG=Hs.36508 Chediak-Higashi syndrome 1 /FL=gb:U84744.1 U84744 lysosomal trafficking regulator LYST 1130 NM_000081 /// NM_001005736 /// NR_102436 /// XM_005273027 /// XM_005273028 /// XM_005273029 /// XM_005273030 /// XM_006711731 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from sequence or structural similarity /// 0032438 // melanosome organization // inferred from sequence or structural similarity /// 0032510 // endosome to lysosome transport via multivesicular body sorting pathway // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 210944_s_at BC003169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003169.1 /DEF=Homo sapiens, Similar to calpain 3, (p94), clone MGC:4403, mRNA, complete cds. /FEA=mRNA /PROD=Similar to calpain 3, (p94) /DB_XREF=gi:13111992 /UG=Hs.40300 calpain 3, (p94) /FL=gb:BC003169.1 BC003169 calpain 3, (p94) CAPN3 825 NM_000070 /// NM_024344 /// NM_173087 /// NM_173088 /// NM_173089 /// NM_173090 /// NM_212465 /// NR_027911 /// NR_027912 0001896 // autolysis // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0014718 // positive regulation of satellite cell activation involved in skeletal muscle regeneration // inferred from sequence or structural similarity /// 0014850 // response to muscle activity // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // traceable author statement /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0045661 // regulation of myoblast differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0061061 // muscle structure development // inferred from sequence or structural similarity /// 0070315 // G1 to G0 transition involved in cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071472 // cellular response to salt stress // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0008307 // structural constituent of muscle // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from sequence or structural similarity /// 0031432 // titin binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055103 // ligase regulator activity // inferred from direct assay 210945_at BC005305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005305.1 /DEF=Homo sapiens, Similar to collagen, type IV, alpha 6, clone MGC:12376, mRNA, complete cds. /FEA=mRNA /PROD=Similar to collagen, type IV, alpha 6 /DB_XREF=gi:13529040 /UG=Hs.408 collagen, type IV, alpha 6 /FL=gb:BC005305.1 BC005305 collagen, type IV, alpha 6 COL4A6 1288 NM_001287758 /// NM_001287759 /// NM_001287760 /// NM_001847 /// NM_033641 /// XM_006724617 /// XM_006724618 0007155 // cell adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005198 // structural molecule activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation 210946_at AF014403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF014403.1 /DEF=Homo sapiens type-2 phosphatidic acid phosphatase alpha-2 (PAP2-a2) mRNA, complete cds. /FEA=mRNA /GEN=PAP2-a2 /PROD=type-2 phosphatidic acid phosphatase alpha-2 /DB_XREF=gi:3123849 /UG=Hs.41569 phosphatidic acid phosphatase type 2A /FL=gb:AF014403.1 AF014403 phosphatidic acid phosphatase type 2A PPAP2A 8611 NM_003711 /// NM_176895 /// NR_103485 /// XM_006714724 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0008354 // germ cell migration // traceable author statement /// 0019216 // regulation of lipid metabolic process // non-traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046839 // phospholipid dephosphorylation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from direct assay /// 0008195 // phosphatidate phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 210947_s_at J04810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04810.1 /DEF=Human MSH3 gene, complete cds. /FEA=mRNA /PROD=MSH3 /DB_XREF=gi:181841 /UG=Hs.42674 mutS (E. coli) homolog 3 /FL=gb:J04810.1 J04810 mutS homolog 3 MSH3 4437 NM_002439 0000710 // meiotic mismatch repair // not recorded /// 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // not recorded /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000228 // nuclear chromosome // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032302 // MutSbeta complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000403 // Y-form DNA binding // not recorded /// 0000404 // heteroduplex DNA loop binding // not recorded /// 0000406 // double-strand/single-strand DNA junction binding // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032139 // dinucleotide insertion or deletion binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032181 // dinucleotide repeat insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay 210948_s_at AF294627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF294627.1 /DEF=Homo sapiens lymphoid enhancer factor 1 isoform (LEF1) mRNA, complete cds. /FEA=mRNA /GEN=LEF1 /PROD=lymphoid enhancer factor 1 isoform /DB_XREF=gi:11024343 /UG=Hs.44865 lymphoid enhancer binding factor-1 /FL=gb:AF294627.1 AF294627 lymphoid enhancer-binding factor 1 LEF1 51176 NM_001130713 /// NM_001130714 /// NM_001166119 /// NM_016269 /// XM_005263046 /// XM_005263047 /// XM_005263048 /// XM_006714233 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001755 // neural crest cell migration // not recorded /// 0001756 // somitogenesis // not recorded /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016202 // regulation of striated muscle tissue development // not recorded /// 0021542 // dentate gyrus development // not recorded /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // not recorded /// 0021861 // forebrain radial glial cell differentiation // not recorded /// 0021873 // forebrain neuroblast division // not recorded /// 0021879 // forebrain neuron differentiation // not recorded /// 0021943 // formation of radial glial scaffolds // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030223 // neutrophil differentiation // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // not recorded /// 0030854 // positive regulation of granulocyte differentiation // inferred from direct assay /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030879 // mammary gland development // not recorded /// 0032696 // negative regulation of interleukin-13 production // inferred from direct assay /// 0032713 // negative regulation of interleukin-4 production // inferred from direct assay /// 0032714 // negative regulation of interleukin-5 production // inferred from direct assay /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042100 // B cell proliferation // not recorded /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from mutant phenotype /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0045063 // T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046632 // alpha-beta T cell differentiation // not recorded /// 0048069 // eye pigmentation // not recorded /// 0048341 // paraxial mesoderm formation // not recorded /// 0048468 // cell development // inferred from electronic annotation /// 0048747 // muscle fiber development // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060325 // face morphogenesis // not recorded /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060561 // apoptotic process involved in morphogenesis // not recorded /// 0060710 // chorio-allantoic fusion // not recorded /// 0061153 // trachea gland development // not recorded /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from mutant phenotype /// 0071866 // negative regulation of apoptotic process in bone marrow // inferred from mutant phenotype /// 0071895 // odontoblast differentiation // not recorded /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 0090068 // positive regulation of cell cycle process // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0035326 // enhancer binding // inferred from direct assay /// 0042393 // histone binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 210949_s_at BC000533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000533.1 /DEF=Homo sapiens, Similar to eukaryotic translation initiation factor 3, subunit 8 (110kD), clone MGC:8693, mRNA, complete cds. /FEA=mRNA /PROD=Similar to eukaryotic translation initiationfactor 3, subunit 8 (110kD) /DB_XREF=gi:12653522 /UG=Hs.4835 eukaryotic translation initiation factor 3, subunit 8 (110kD) /FL=gb:BC000533.1 BC000533 eukaryotic translation initiation factor 3, subunit C /// eukaryotic translation initiation factor 3, subunit C-like EIF3C /// EIF3CL 8663 /// 728689 NM_001037808 /// NM_001099661 /// NM_001199142 /// NM_001267574 /// NM_001286478 /// NM_003752 /// XM_005255535 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 210950_s_at BC003573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003573.1 /DEF=Homo sapiens, farnesyl-diphosphate farnesyltransferase 1, clone MGC:2200, mRNA, complete cds. /FEA=mRNA /PROD=farnesyl-diphosphate farnesyltransferase 1 /DB_XREF=gi:13097746 /UG=Hs.48876 farnesyl-diphosphate farnesyltransferase 1 /FL=gb:BC003573.1 BC003573 farnesyl-diphosphate farnesyltransferase 1 FDFT1 2222 NM_001287742 /// NM_001287743 /// NM_001287744 /// NM_001287745 /// NM_001287747 /// NM_001287748 /// NM_001287749 /// NM_001287750 /// NM_001287751 /// NM_001287756 /// NM_004462 /// XM_006716247 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045338 // farnesyl diphosphate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004310 // farnesyl-diphosphate farnesyltransferase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016765 // transferase activity, transferring alkyl or aryl (other than methyl) groups // inferred from electronic annotation /// 0051996 // squalene synthase activity // inferred from electronic annotation 210951_x_at AF125393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125393.1 /DEF=Homo sapiens Rab27 isoform mRNA, complete cds. /FEA=mRNA /PROD=Rab27 isoform /DB_XREF=gi:5410356 /UG=Hs.50477 RAB27A, member RAS oncogene family /FL=gb:AF125393.1 AF125393 RAB27A, member RAS oncogene family RAB27A 5873 NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation 210952_at BC001259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001259.1 /DEF=Homo sapiens, Similar to adaptor-related protein complex 4, sigma 1 subunit, clone MGC:5011, mRNA, complete cds. /FEA=mRNA /PROD=Similar to adaptor-related protein complex 4,sigma 1 subunit /DB_XREF=gi:12654832 /UG=Hs.50628 adaptor-related protein complex 4, sigma 1 subunit /FL=gb:BC001259.1 BC001259 adaptor-related protein complex 4, sigma 1 subunit AP4S1 11154 NM_001128126 /// NM_001254726 /// NM_001254727 /// NM_001254728 /// NM_001254729 /// NM_007077 /// XM_005267293 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 210953_at AF201292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201292.1 /DEF=Homo sapiens TSC22-related inducible leucine zipper 4a (TILZ4a) mRNA, complete cds. /FEA=mRNA /GEN=TILZ4a /PROD=TSC22-related inducible leucine zipper 4a /DB_XREF=gi:11907585 /UG=Hs.52526 KIAA0669 gene product /FL=gb:AF201292.1 AF201292 TSC22 domain family, member 2 TSC22D2 9819 NM_014779 /// XM_005247920 /// XR_427388 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 210954_s_at AF201292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201292.1 /DEF=Homo sapiens TSC22-related inducible leucine zipper 4a (TILZ4a) mRNA, complete cds. /FEA=mRNA /GEN=TILZ4a /PROD=TSC22-related inducible leucine zipper 4a /DB_XREF=gi:11907585 /UG=Hs.52526 KIAA0669 gene product /FL=gb:AF201292.1 AF201292 TSC22 domain family, member 2 TSC22D2 9819 NM_014779 /// XM_005247920 /// XR_427388 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 210955_at U86214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U86214.1 /DEF=Human Fas-associated death domain protein interleukin-1b-converting enzyme 2 mRNA, complete cds. /FEA=mRNA /PROD=Fas-associated death domain proteininterleukin-1b-converting enzyme 2 /DB_XREF=gi:1835778 /UG=Hs.5353 caspase 10, apoptosis-related cysteine protease /FL=gb:U86214.1 U86214 caspase 10, apoptosis-related cysteine peptidase CASP10 843 NM_001206524 /// NM_001206542 /// NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 /// XM_005246907 /// XM_005246909 /// XM_005246910 /// XM_005246911 /// XM_006712796 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0045087 // innate immune response // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0097342 // ripoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 210956_at U42387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U42387.1 /DEF=Human pancreatic polypeptide receptor mRNA, complete cds. /FEA=mRNA /PROD=pancreatic polypeptide receptor /DB_XREF=gi:1314327 /UG=Hs.54426 pancreatic polypeptide receptor 1 /FL=gb:U42387.1 gb:NM_005972.1 U42387 neuropeptide Y receptor type 4-like /// neuropeptide Y receptor Y4 LOC100996758 /// NPY4R 5540 /// 100996758 NM_001278794 /// NM_001278795 /// NM_005972 /// XM_005277644 /// XM_006717545 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008015 // blood circulation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001601 // peptide YY receptor activity // inferred from electronic annotation /// 0001602 // pancreatic polypeptide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004983 // neuropeptide Y receptor activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 210957_s_at L76569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76569.1 /DEF=Homo sapiens (clones cYG3, B5P6C4) fragile X E mental retardation syndrome protein (FMR2) mRNA, complete cds. /FEA=mRNA /GEN=FMR2 /PROD=fragile X E mental retardation syndrome protein /DB_XREF=gi:1313885 /UG=Hs.54472 fragile X mental retardation 2 /FL=gb:L76569.1 L76569 AF4/FMR2 family, member 2 AFF2 2334 NM_001169122 /// NM_001169123 /// NM_001169124 /// NM_001169125 /// NM_001170628 /// NM_002025 0006397 // mRNA processing // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0002151 // G-quadruplex RNA binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation 210958_s_at BC003646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003646.1 /DEF=Homo sapiens, clone MGC:4693, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4693) /DB_XREF=gi:13177744 /UG=Hs.54985 KIAA0303 protein /FL=gb:BC003646.1 BC003646 microtubule associated serine/threonine kinase family member 4 MAST4 375449 NM_001164664 /// NM_001290226 /// NM_001290227 /// NM_001290228 /// NM_015183 /// NM_198828 /// XM_005248498 /// XM_006714602 /// XM_006714603 /// XM_006714604 /// XM_006714605 /// XM_006714606 /// XM_006714607 /// XM_006714608 /// XM_006714609 /// XM_006714610 /// XM_006714611 /// XM_006714612 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210959_s_at AF113128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113128.1 /DEF=Homo sapiens steroid-5-alpha-reductase isoform mRNA, complete cds. /FEA=mRNA /PROD=steroid-5-alpha-reductase isoform /DB_XREF=gi:6523818 /UG=Hs.552 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) /FL=gb:AF113128.1 AF113128 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) SRD5A1 6715 NM_001047 /// XR_427663 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0007530 // sex determination // non-traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003865 // 3-oxo-5-alpha-steroid 4-dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0047751 // cholestenone 5-alpha-reductase activity // inferred from electronic annotation 210960_at M76446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76446.1 /DEF=Human alpha-A1-adrenergic receptor mRNA, complete cds. /FEA=mRNA /PROD=alpha-1A-adrenergic receptor /DB_XREF=gi:177806 /UG=Hs.557 adrenergic, alpha-1D-, receptor /FL=gb:M76446.1 M76446 adrenoceptor alpha 1D ADRA1D 146 NM_000678 0001986 // negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from electronic annotation 210961_s_at M76446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76446.1 /DEF=Human alpha-A1-adrenergic receptor mRNA, complete cds. /FEA=mRNA /PROD=alpha-1A-adrenergic receptor /DB_XREF=gi:177806 /UG=Hs.557 adrenergic, alpha-1D-, receptor /FL=gb:M76446.1 M76446 adrenoceptor alpha 1D ADRA1D 146 NM_000678 0001986 // negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from electronic annotation 210962_s_at AB019691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB019691.1 /DEF=Homo sapiens mRNA for Centrosome- and Golgi-localized PKN-associated protein (CG-NAP), complete cds. /FEA=mRNA /GEN=cg-nap /PROD=Centrosome- and Golgi-localized PKN-associatedprotein (CG-NAP) /DB_XREF=gi:5051742 /UG=Hs.58103 A kinase (PRKA) anchor protein (yotiao) 9 /FL=gb:AB019691.1 AB019691 A kinase (PRKA) anchor protein 9 AKAP9 10142 NM_005751 /// NM_147166 /// NM_147171 /// NM_147185 /// XM_005250102 /// XM_005250103 /// XM_006715827 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 210963_s_at U94363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94363.1 /DEF=Homo sapiens glycogenin-2 beta (glycogenin-2) mRNA, complete cds. /FEA=mRNA /GEN=glycogenin-2 /PROD=glycogenin-2 beta /DB_XREF=gi:2618767 /UG=Hs.58589 glycogenin 2 /FL=gb:U94363.1 U94363 glycogenin 2 GYG2 8908 NM_001079855 /// NM_001184702 /// NM_001184703 /// NM_001184704 /// NM_003918 /// XM_005274617 /// XM_005274618 /// XM_005274619 /// XM_005274621 /// XM_005274622 /// XM_006724521 /// XM_006724522 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210964_s_at U94364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94364.1 /DEF=Homo sapiens glycogenin-2 gamma (glycogenin-2) mRNA, complete cds. /FEA=mRNA /GEN=glycogenin-2 /PROD=glycogenin-2 gamma /DB_XREF=gi:2618769 /UG=Hs.58589 glycogenin 2 /FL=gb:U94364.1 U94364 glycogenin 2 GYG2 8908 NM_001079855 /// NM_001184702 /// NM_001184703 /// NM_001184704 /// NM_003918 /// XM_005274617 /// XM_005274618 /// XM_005274619 /// XM_005274621 /// XM_005274622 /// XM_006724521 /// XM_006724522 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 210965_x_at BC001274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001274.1 /DEF=Homo sapiens, Similar to cell division cycle 2-like 5 (cholinesterase-related cell division controller), clone MGC:5091, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cell division cycle 2-like 5(cholinesterase-related cell division controller) /DB_XREF=gi:12654860 /UG=Hs.59498 cell division cycle 2-like 5 (cholinesterase-related cell division controller) /FL=gb:BC001274.1 BC001274 cyclin-dependent kinase 13 CDK13 8621 NM_003718 /// NM_031267 0000380 // alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0000380 // alternative mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210966_x_at BC001460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001460.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ10378, clone MGC:2954, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ10378 /DB_XREF=gi:12655204 /UG=Hs.6214 KIAA0731 protein /FL=gb:BC001460.1 BC001460 La ribonucleoprotein domain family, member 1 LARP1 23367 NM_015315 /// NM_033551 /// XM_005268404 /// XM_005268406 /// XM_005268407 /// XM_005268408 /// XM_006714775 /// XM_006714776 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031931 // TORC1 complex // inferred from direct assay 0000339 // RNA cap binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 210967_x_at M92301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M92301.1 /DEF=Human voltage-dependent calcium channel beta-1 subunit, complete cds. /FEA=mRNA /PROD=voltage-dependent calcium channel beta-1subunit /DB_XREF=gi:179801 /UG=Hs.635 calcium channel, voltage-dependent, beta 1 subunit /FL=gb:M92301.1 gb:L06112.1 M92301 calcium channel, voltage-dependent, beta 1 subunit CACNB1 782 NM_000723 /// NM_199247 /// NM_199248 /// XM_005257645 /// XM_005257646 /// XM_005257647 /// XM_006722072 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from electronic annotation 210968_s_at AF333336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF333336.1 /DEF=Homo sapiens testis specific reticulon 5 protein mRNA, complete cds. /FEA=mRNA /PROD=testis specific reticulon 5 protein /DB_XREF=gi:13377627 /UG=Hs.65450 reticulon 4 /FL=gb:AF333336.1 AF333336 reticulon 4 RTN4 57142 NM_007008 /// NM_020532 /// NM_153828 /// NM_207520 /// NM_207521 /// XM_005264434 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0021801 // cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from direct assay /// 0030517 // negative regulation of axon extension // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0051960 // regulation of nervous system development // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from sequence or structural similarity 0005622 // intracellular // inferred from mutant phenotype /// 0005635 // nuclear envelope // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 210969_at AF118089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118089.1 /DEF=Homo sapiens PRO2042 mRNA, complete cds. /FEA=mRNA /PROD=PRO2042 /DB_XREF=gi:6650823 /UG=Hs.69171 protein kinase C-like 2 /FL=gb:AF118089.1 AF118089 protein kinase N2 PKN2 5586 NM_006256 /// XM_005271031 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010631 // epithelial cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 2000145 // regulation of cell motility // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 210970_s_at AF235049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF235049.1 /DEF=Homo sapiens putative BTK-binding protein mRNA, complete cds. /FEA=mRNA /PROD=putative BTK-binding protein /DB_XREF=gi:11036533 /UG=Hs.7387 DKFZP564B116 protein /FL=gb:AF235049.1 AF235049 inhibitor of Bruton agammaglobulinemia tyrosine kinase IBTK 25998 NM_015525 /// XM_006715453 /// XM_006715454 /// XM_006715455 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay 210971_s_at AB000815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000815.1 /DEF=Homo sapiens mRNA for BMAL1e, complete cds. /FEA=mRNA /PROD=BMAL1e /DB_XREF=gi:2094740 /UG=Hs.74515 aryl hydrocarbon receptor nuclear translocator-like /FL=gb:AB000815.1 AB000815 aryl hydrocarbon receptor nuclear translocator-like ARNTL 406 NM_001030272 /// NM_001030273 /// NM_001178 /// XM_005252928 /// XM_005252929 /// XM_005252930 /// XM_006718233 /// XM_006718234 /// XM_006718235 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // traceable author statement /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090403 // oxidative stress-induced premature senescence // inferred from sequence or structural similarity /// 2000074 // regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity /// 2000772 // regulation of cellular senescence // inferred from sequence or structural similarity /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017162 // aryl hydrocarbon receptor binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay 210972_x_at M15565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M15565.1 /DEF=Human T-cell receptor rearranged alpha-chain V-region (V-D-J) mRNA, complete cds. /FEA=mRNA /GEN=TCRA /DB_XREF=gi:338765 /UG=Hs.74647 Human T-cell receptor active alpha-chain mRNA from JM cell line, complete cds /FL=gb:M15565.1 M15565 T cell receptor alpha constant /// T cell receptor alpha joining 17 /// T cell receptor alpha variable 20 /// T cell receptor delta variable 2 TRAC /// TRAJ17 /// TRAV20 /// TRDV2 28517 /// 28663 /// 28738 /// 28755 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 210973_s_at M63889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M63889.1 /DEF=Human heparin-binding growth factor receptor (HBGF-R-alpha-a3) mRNA, complete cds. /FEA=mRNA /GEN=HBGF-R /PROD=heparin-binding growth factor receptor /DB_XREF=gi:183882 /UG=Hs.748 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) /FL=gb:M63889.1 M63889 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 210974_s_at AF130042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130042.1 /DEF=Homo sapiens clone FLB0124 PRO0039 mRNA, complete cds. /FEA=mRNA /PROD=PRO0039 /DB_XREF=gi:11493394 /UG=Hs.75056 adaptor-related protein complex 3, delta 1 subunit /FL=gb:AF130042.1 AF130042 adaptor-related protein complex 3, delta 1 subunit AP3D1 8943 NM_001077523 /// NM_001261826 /// NM_003938 /// XM_006722932 0006726 // eye pigment biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred by curator /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0048499 // synaptic vesicle membrane organization // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0061088 // regulation of sequestering of zinc ion // inferred from mutant phenotype /// 0072657 // protein localization to membrane // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 210975_x_at BC000377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000377.1 /DEF=Homo sapiens, Similar to Fas-activated serinethreonine kinase, clone MGC:8381, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Fas-activated serinethreoninekinase /DB_XREF=gi:12653218 /UG=Hs.75087 Fas-activated serinethreonine kinase /FL=gb:BC000377.1 BC000377 Fas-activated serine/threonine kinase FASTK 10922 NM_001258461 /// NM_006712 /// NM_033015 /// XM_005249932 /// XM_005249933 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033867 // Fas-activated serine/threonine kinase activity // inferred from electronic annotation 210976_s_at U24183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24183.1 /DEF=Human phosphofructokinase (PFKM) mRNA, complete cds. /FEA=mRNA /GEN=PFKM /PROD=phosphofructokinase /DB_XREF=gi:975289 /UG=Hs.75160 phosphofructokinase, muscle /FL=gb:U24183.1 U24183 phosphofructokinase, muscle PFKM 5213 NM_000289 /// NM_001166686 /// NM_001166687 /// NM_001166688 /// XM_005268974 /// XM_005268975 /// XM_005268976 /// XM_005268977 /// XM_005268978 /// XM_005268979 /// XM_005268980 /// XM_006719463 /// XM_006719464 0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006002 // fructose 6-phosphate metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from mutant phenotype /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from mutant phenotype /// 0046835 // carbohydrate phosphorylation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0003872 // 6-phosphofructokinase activity // inferred from mutant phenotype /// 0003872 // 6-phosphofructokinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008443 // phosphofructokinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070061 // fructose binding // inferred from direct assay 210977_s_at AB029348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB029348.1 /DEF=Homo sapiens mRNA for transcription factor HSF4b isoform, complete cds. /FEA=mRNA /PROD=transcription factor HSF4b isoform /DB_XREF=gi:5921134 /UG=Hs.75486 heat shock transcription factor 4 /FL=gb:AB029348.1 AB029348 heat shock transcription factor 4 HSF4 3299 NM_001040667 /// NM_001538 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 210978_s_at BC002616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002616.1 /DEF=Homo sapiens, transgelin 2, clone MGC:2989, mRNA, complete cds. /FEA=mRNA /PROD=transgelin 2 /DB_XREF=gi:12803566 /UG=Hs.75725 transgelin 2 /FL=gb:BC002616.1 BC002616 transgelin 2 TAGLN2 8407 NM_001277223 /// NM_001277224 /// NM_003564 0007517 // muscle organ development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from direct assay 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 210979_at U47674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U47674.1 /DEF=Homo sapiens putative heart protein PHP mRNA, complete cds. /FEA=mRNA /PROD=PHP /DB_XREF=gi:3860239 /UG=Hs.75811 N-acylsphingosine amidohydrolase (acid ceramidase) /FL=gb:U47674.1 U47674 N-acylsphingosine amidohydrolase (acid ceramidase) 1 ASAH1 427 NM_001127505 /// NM_004315 /// NM_177924 /// XM_005273504 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017040 // ceramidase activity // traceable author statement 210980_s_at U47674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U47674.1 /DEF=Homo sapiens putative heart protein PHP mRNA, complete cds. /FEA=mRNA /PROD=PHP /DB_XREF=gi:3860239 /UG=Hs.75811 N-acylsphingosine amidohydrolase (acid ceramidase) /FL=gb:U47674.1 U47674 N-acylsphingosine amidohydrolase (acid ceramidase) 1 ASAH1 427 NM_001127505 /// NM_004315 /// NM_177924 /// XM_005273504 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017040 // ceramidase activity // traceable author statement 210981_s_at AF040751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040751.1 /DEF=Homo sapiens G protein-coupled receptor kinase 6, splice variant B (GRK6) mRNA, complete cds. /FEA=mRNA /GEN=GRK6 /PROD=G protein-coupled receptor kinase 6, splicevariant B /DB_XREF=gi:3005015 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:AF040751.1 AF040751 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 210982_s_at M60333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60333.1 /DEF=Human MHC class II HLA-DRA mRNA, complete cds. /FEA=mRNA /GEN=HLA-DRA /PROD=MHC cell surface glycoprotein /DB_XREF=gi:188268 /UG=Hs.76807 major histocompatibility complex, class II, DR alpha /FL=gb:M60333.1 M60333 major histocompatibility complex, class II, DR alpha HLA-DRA 3122 NM_019111 0002376 // immune system process // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 210983_s_at AF279900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279900.1 /DEF=Homo sapiens PNAS-146 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-146 /DB_XREF=gi:12751125 /UG=Hs.77152 minichromosome maintenance deficient (S. cerevisiae) 7 /FL=gb:AF279900.1 AF279900 minichromosome maintenance complex component 7 MCM7 4176 NM_001278595 /// NM_005916 /// NM_182776 /// XM_005250348 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0042555 // MCM complex // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 210984_x_at U95089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U95089.1 /DEF=Human truncated epidermal growth factor receptor-like protein precursor mRNA, complete cds. /FEA=mRNA /PROD=truncated epidermal growth factor receptor-likeprotein precursor /DB_XREF=gi:2051984 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:U95089.1 U95089 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 210985_s_at AF056322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF056322.1 /DEF=Homo sapiens SP100-HMG nuclear autoantigen (SP100) mRNA, complete cds. /FEA=mRNA /GEN=SP100 /PROD=SP100-HMG nuclear autoantigen /DB_XREF=gi:3252910 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:AF056322.1 AF056322 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 210986_s_at Z24727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z24727.1 /DEF=H.sapiens tropomyosin isoform mRNA, complete CDS. /FEA=mRNA /PROD=tropomyosin isoform /DB_XREF=gi:854188 /UG=Hs.77899 tropomyosin 1 (alpha) /FL=gb:Z24727.1 Z24727 tropomyosin 1 (alpha) TPM1 7168 NM_000366 /// NM_001018004 /// NM_001018005 /// NM_001018006 /// NM_001018007 /// NM_001018008 /// NM_001018020 /// XM_005254637 /// XM_005254638 /// XM_005254639 /// XM_005254640 /// XM_005254641 /// XM_005254643 /// XM_005254644 /// XM_005254645 /// XM_005254646 /// XM_005254647 /// XM_005254648 /// XM_005254649 /// XM_005254650 /// XM_005254651 /// XM_005254652 /// XM_005254653 /// XM_006720667 /// XM_006720668 /// XM_006720669 /// XR_429470 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003065 // positive regulation of heart rate by epinephrine // inferred from sequence or structural similarity /// 0006413 // translational initiation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from sequence or structural similarity /// 0030049 // muscle filament sliding // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032059 // bleb // inferred from mutant phenotype /// 0032587 // ruffle membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 210987_x_at M19267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M19267.1 /DEF=Human tropomyosin mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:339943 /UG=Hs.77899 tropomyosin 1 (alpha) /FL=gb:M19267.1 M19267 tropomyosin 1 (alpha) TPM1 7168 NM_000366 /// NM_001018004 /// NM_001018005 /// NM_001018006 /// NM_001018007 /// NM_001018008 /// NM_001018020 /// XM_005254637 /// XM_005254638 /// XM_005254639 /// XM_005254640 /// XM_005254641 /// XM_005254643 /// XM_005254644 /// XM_005254645 /// XM_005254646 /// XM_005254647 /// XM_005254648 /// XM_005254649 /// XM_005254650 /// XM_005254651 /// XM_005254652 /// XM_005254653 /// XM_006720667 /// XM_006720668 /// XM_006720669 /// XR_429470 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003065 // positive regulation of heart rate by epinephrine // inferred from sequence or structural similarity /// 0006413 // translational initiation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from sequence or structural similarity /// 0030049 // muscle filament sliding // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032059 // bleb // inferred from mutant phenotype /// 0032587 // ruffle membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 210988_s_at AF123538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123538.1 /DEF=Homo sapiens clone 17B prune protein mRNA, complete cds., alternatively spliced. /FEA=mRNA /PROD=prune protein /DB_XREF=gi:12655789 /UG=Hs.78524 TcD37 homolog /FL=gb:AF123538.1 AF123538 prune exopolyphosphatase PRUNE 58497 NM_021222 /// XM_005245393 /// XM_005245394 /// XM_005245396 /// XM_005245397 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004427 // inorganic diphosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 210989_at U77706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U77706.1 /DEF=Human laminin alpha 4 chain (LAMA4*-1) mRNA, complete cds. /FEA=mRNA /GEN=LAMA4*-1 /PROD=laminin alpha 4 chain /DB_XREF=gi:1684836 /UG=Hs.78672 laminin, alpha 4 /FL=gb:U77706.1 U77706 laminin, alpha 4 LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement 210990_s_at U77706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U77706.1 /DEF=Human laminin alpha 4 chain (LAMA4*-1) mRNA, complete cds. /FEA=mRNA /GEN=LAMA4*-1 /PROD=laminin alpha 4 chain /DB_XREF=gi:1684836 /UG=Hs.78672 laminin, alpha 4 /FL=gb:U77706.1 U77706 laminin, alpha 4 LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 210991_s_at BC003103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003103.1 /DEF=Homo sapiens, KIAA0237 gene product, clone MGC:1884, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0237 gene product /DB_XREF=gi:13111870 /UG=Hs.78748 KIAA0237 gene product /FL=gb:BC003103.1 BC003103 regulating synaptic membrane exocytosis 3 RIMS3 9783 NM_014747 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation 210992_x_at U90939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90939.1 /DEF=Homo sapiens cell-type natural killer cells Fc gamma receptor IIc2 (Fc-gammaRIIC) mRNA, complete cds. /FEA=mRNA /GEN=Fc-gammaRIIC /PROD=Fc gamma receptor IIc2 /DB_XREF=gi:2149627 /UG=Hs.78864 Fc fragment of IgG, low affinity IIa, receptor for (CD32) /FL=gb:U90938.1 gb:U90939.1 U90939 Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) FCGR2C 9103 NM_001005410 /// NM_001005411 /// NM_001005412 /// NM_201563 /// NR_047648 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from electronic annotation 210993_s_at U54826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U54826.1 /DEF=Human mad-related protein MADR1 mRNA, complete cds. /FEA=mRNA /PROD=mad-related protein MADR1 /DB_XREF=gi:1332713 /UG=Hs.79067 MAD (mothers against decapentaplegic, Drosophila) homolog 1 /FL=gb:U54826.1 gb:U59912.1 U54826 SMAD family member 1 SMAD1 4086 NM_001003688 /// NM_005900 /// XM_005262991 /// XM_005262992 /// XM_005262993 /// XM_006714217 0000165 // MAPK cascade // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001710 // mesodermal cell fate commitment // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042592 // homeostatic process // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction 210994_x_at AF230398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230398.1 /DEF=Homo sapiens tripartite motif protein TRIM23 beta mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM23 beta /DB_XREF=gi:12275884 /UG=Hs.792 ADP-ribosylation factor domain protein 1, 64kD /FL=gb:AF230398.1 AF230398 tripartite motif containing 23 TRIM23 373 NM_001656 /// NM_033227 /// NM_033228 /// XM_005248497 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0000139 // Golgi membrane // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210995_s_at AF230399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230399.1 /DEF=Homo sapiens tripartite motif protein TRIM23 gamma mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM23 gamma /DB_XREF=gi:12275886 /UG=Hs.792 ADP-ribosylation factor domain protein 1, 64kD /FL=gb:AF230399.1 AF230399 tripartite motif containing 23 TRIM23 373 NM_001656 /// NM_033227 /// NM_033228 /// XM_005248497 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0000139 // Golgi membrane // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 210996_s_at U43430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43430.1 /DEF=Human epsilon isoform 14-3-3 protein mRNA, complete cds. /FEA=mRNA /PROD=14-3-3 protein /DB_XREF=gi:4096984 /UG=Hs.79474 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, epsilon polypeptide /FL=gb:U43399.1 gb:U43430.1 U43430 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon YWHAE 7531 NM_006761 /// NR_024058 /// XM_005256784 /// XM_006725298 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003064 // regulation of heart rate by hormone // non-traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0035308 // negative regulation of protein dephosphorylation // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred by curator /// 0086091 // regulation of heart rate by cardiac conduction // inferred by curator /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1902309 // negative regulation of peptidyl-serine dephosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005871 // kinesin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 210997_at M77227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M77227.1 /DEF=H.sapiens competitive HGF antagonist mRNA, complete cds. /FEA=mRNA /PROD=competitive HGF antagonist /DB_XREF=gi:184029 /UG=Hs.809 hepatocyte growth factor (hepapoietin A; scatter factor) /FL=gb:M77227.1 gb:L02931.1 M77227 hepatocyte growth factor (hepapoietin A; scatter factor) HGF 3082 NM_000601 /// NM_001010931 /// NM_001010932 /// NM_001010933 /// NM_001010934 /// XM_006715956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210998_s_at M77227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M77227.1 /DEF=H.sapiens competitive HGF antagonist mRNA, complete cds. /FEA=mRNA /PROD=competitive HGF antagonist /DB_XREF=gi:184029 /UG=Hs.809 hepatocyte growth factor (hepapoietin A; scatter factor) /FL=gb:M77227.1 gb:L02931.1 M77227 hepatocyte growth factor (hepapoietin A; scatter factor) HGF 3082 NM_000601 /// NM_001010931 /// NM_001010932 /// NM_001010933 /// NM_001010934 /// XM_006715956 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 210999_s_at U66065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66065.1 /DEF=Human Grb10- and Grb-IR-related splice variant 1 mRNA, complete cds. /FEA=mRNA /PROD=Grb10- and Grb-IR-related splice variant 1 /DB_XREF=gi:1518100 /UG=Hs.81875 growth factor receptor-bound protein 10 /FL=gb:U66065.1 gb:U69276.1 gb:NM_005311.1 U66065 growth factor receptor-bound protein 10 GRB10 2887 NM_001001549 /// NM_001001550 /// NM_001001555 /// NM_005311 /// XM_005271760 /// XM_005271761 /// XM_005271765 /// XM_005271766 /// XM_005271767 /// XM_006715703 /// XM_006715704 /// XM_006715705 0007165 // signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 211000_s_at AB015706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB015706.1 /DEF=Homo sapiens mRNA for gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form (gp130-RAPS), complete cds. /FEA=mRNA /GEN=gp130 /PROD=gp130 of the rheumatoid arthritis antigenicpeptide-bearing soluble form (gp130-RAPS) /DB_XREF=gi:4972293 /UG=Hs.82065 interleukin 6 signal transducer (gp130, oncostatin M receptor) /FL=gb:AB015706.1 AB015706 interleukin 6 signal transducer IL6ST 3572 NM_001190981 /// NM_002184 /// NM_175767 /// NR_120480 /// XM_005248496 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0002821 // positive regulation of adaptive immune response // inferred by curator /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038154 // interleukin-11-mediated signaling pathway // inferred from electronic annotation /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from genetic interaction /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070106 // interleukin-27-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070110 // ciliary neurotrophic factor receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from genetic interaction /// 0004921 // interleukin-11 receptor activity // inferred from electronic annotation /// 0004923 // leukemia inhibitory factor receptor activity // inferred from genetic interaction /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019970 // interleukin-11 binding // inferred from electronic annotation /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred by curator 211001_at AF230389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230389.1 /DEF=Homo sapiens tripartite motif protein TRIM29 beta mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM29 beta /DB_XREF=gi:12275865 /UG=Hs.82237 ataxia-telangiectasia group D-associated protein /FL=gb:AF230389.1 AF230389 tripartite motif containing 29 TRIM29 23650 NM_012101 /// NM_058193 /// XM_005271487 /// XM_005271490 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 1900181 // negative regulation of protein localization to nucleus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0002039 // p53 binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211002_s_at AF230389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230389.1 /DEF=Homo sapiens tripartite motif protein TRIM29 beta mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM29 beta /DB_XREF=gi:12275865 /UG=Hs.82237 ataxia-telangiectasia group D-associated protein /FL=gb:AF230389.1 AF230389 tripartite motif containing 29 TRIM29 23650 NM_012101 /// NM_058193 /// XM_005271487 /// XM_005271490 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 1900181 // negative regulation of protein localization to nucleus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0002039 // p53 binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211003_x_at BC003551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003551.1 /DEF=Homo sapiens, Similar to transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), clone MGC:1193, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transglutaminase 2 (C polypeptide,protein-glutamine-gamma-glutamyltransferase) /DB_XREF=gi:13097680 /UG=Hs.8265 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:BC003551.1 BC003551 transglutaminase 2 TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from mutant phenotype /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211004_s_at BC002553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002553.1 /DEF=Homo sapiens, Similar to aldehyde dehydrogenase 7, clone MGC:1805, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aldehyde dehydrogenase 7 /DB_XREF=gi:12803456 /UG=Hs.83155 aldehyde dehydrogenase 3 family, member B1 /FL=gb:BC002553.1 BC002553 aldehyde dehydrogenase 3 family, member B1 ALDH3B1 221 NM_000694 /// NM_001030010 /// NM_001161473 /// NM_001290058 /// NM_001290059 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0046185 // aldehyde catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 211005_at AF036906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF036906.1 /DEF=Homo sapiens linker for activation of T cells (LAT) mRNA, alternatively spliced form, complete cds. /FEA=mRNA /GEN=LAT /PROD=LAT /DB_XREF=gi:2828025 /UG=Hs.83496 linker for activation of T cells /FL=gb:AF036906.1 gb:NM_014387.1 AF036906 linker for activation of T cells LAT 27040 NM_001014987 /// NM_001014988 /// NM_001014989 /// NM_014387 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0010467 // gene expression // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043303 // mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050863 // regulation of T cell activation // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0042629 // mast cell granule // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 211006_s_at L02840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L02840.1 /DEF=Homo sapiens potassium channel Kv2.1 mRNA, complete cds. /FEA=mRNA /PROD=voltage-gated potassium channel /DB_XREF=gi:186797 /UG=Hs.84244 potassium voltage-gated channel, Shab-related subfamily, member 1 /FL=gb:L02840.1 gb:AF026005.1 gb:NM_004975.1 L02840 potassium voltage-gated channel, Shab-related subfamily, member 1 KCNB1 3745 NM_004975 /// XM_006723784 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 211008_s_at BC000744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000744.1 /DEF=Homo sapiens, Similar to ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9), clone MGC:2377, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ubiquitin-conjugating enzyme E2I(homologous to yeast UBC9) /DB_XREF=gi:12653902 /UG=Hs.84285 ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) /FL=gb:BC000744.1 gb:BC004437.1 BC000744 ubiquitin-conjugating enzyme E2I UBE2I 7329 NM_003345 /// NM_194259 /// NM_194260 /// NM_194261 /// XM_005255540 /// XM_005255541 /// XM_006720938 /// XM_006720939 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0033145 // positive regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // traceable author statement /// 0001650 // fibrillar center // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0043398 // HLH domain binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 211009_s_at AF159567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF159567.1 /DEF=Homo sapiens C2H2 (Kruppel-type) zinc finger protein mRNA, complete cds. /FEA=mRNA /PROD=C2H2 (Kruppel-type) zinc finger protein /DB_XREF=gi:5453422 /UG=Hs.86276 C2H2 (Kruppel-type) zinc finger protein /FL=gb:AF159567.1 AF159567 zinc finger protein 271 ZNF271 10778 NM_006629 /// NR_024565 /// NR_024566 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211010_s_at AF031138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031138.1 /DEF=Homo sapiens 1C7 precursor, mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=1C7 precursor /DB_XREF=gi:2623876 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF031138.1 AF031138 natural cytotoxicity triggering receptor 3 NCR3 259197 NM_001145466 /// NM_001145467 /// NM_147130 /// XM_006715049 /// XM_006725031 /// XM_006725478 /// XM_006725692 /// XM_006725808 /// XM_006725902 /// XM_006725903 /// XM_006725989 /// XM_006726081 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211011_at D38163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D38163.1 /DEF=Human mRNA for a1(XIX) collagen chain, complete cds. /FEA=mRNA /PROD=a1(XIX) collagen chain precursor /DB_XREF=gi:624870 /UG=Hs.89457 collagen, type XIX, alpha 1 /FL=gb:NM_001858.1 gb:D38163.1 D38163 collagen, type XIX, alpha 1 COL19A1 1310 NM_001858 0001501 // skeletal system development // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement 211012_s_at BC000080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000080.1 /DEF=Homo sapiens, Similar to promyelocytic leukemia, clone MGC:2268, mRNA, complete cds. /FEA=mRNA /PROD=Similar to promyelocytic leukemia /DB_XREF=gi:12652662 /UG=Hs.89633 promyelocytic leukemia /FL=gb:BC000080.1 BC000080 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 211013_x_at AF230411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230411.1 /DEF=Homo sapiens tripartite motif protein TRIM19 lambda mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM19 lambda /DB_XREF=gi:12275911 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230411.1 AF230411 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 211014_s_at AF230410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230410.1 /DEF=Homo sapiens tripartite motif protein TRIM19 kappa mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM19 kappa /DB_XREF=gi:12275908 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230403.1 gb:AF230410.1 gb:M82829.1 gb:M79464.1 AF230410 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 211015_s_at L12723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L12723.1 /DEF=Human heat shock protein 70 (hsp70) mRNA, complete cds. /FEA=mRNA /GEN=hsp70 /PROD=heat shock protein 70 /DB_XREF=gi:292159 /UG=Hs.90093 heat shock 70kD protein 4 /FL=gb:L12723.1 L12723 heat shock 70kDa protein 4 HSPA4 3308 NM_002154 /// NM_198431 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 211016_x_at BC002526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002526.1 /DEF=Homo sapiens, Similar to heat shock protein, 110 kDa, clone MGC:1548, mRNA, complete cds. /FEA=mRNA /PROD=Similar to heat shock protein, 110 kDa /DB_XREF=gi:12803406 /UG=Hs.90093 heat shock 70kD protein 4 /FL=gb:BC002526.1 BC002526 heat shock 70kDa protein 4 HSPA4 3308 NM_002154 /// NM_198431 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 211017_s_at AF123570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123570.1 /DEF=Homo sapiens neurofibromatosis type 2 protein isoform Mer150 (NF2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=NF2 /PROD=neurofibromatosis type 2 protein isoform Mer150 /DB_XREF=gi:5730867 /UG=Hs.902 neurofibromin 2 (bilateral acoustic neuroma) /FL=gb:AF123570.1 AF123570 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 211018_at D63807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63807.1 /DEF=Human mRNA for lanosterol synthase, complete cds. /FEA=mRNA /PROD=lanosterol synthase /DB_XREF=gi:1019365 /UG=Hs.93199 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) /FL=gb:D63807.1 D63807 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) LSS 4047 NM_001001438 /// NM_001145436 /// NM_001145437 /// NM_002340 /// XM_006724003 /// XM_006724004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000250 // lanosterol synthase activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation 211019_s_at D63807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D63807.1 /DEF=Human mRNA for lanosterol synthase, complete cds. /FEA=mRNA /PROD=lanosterol synthase /DB_XREF=gi:1019365 /UG=Hs.93199 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) /FL=gb:D63807.1 D63807 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) LSS 4047 NM_001001438 /// NM_001145436 /// NM_001145437 /// NM_002340 /// XM_006724003 /// XM_006724004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000250 // lanosterol synthase activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation 211020_at L19659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L19659.1 /DEF=Human I beta 1-6 N-acetylglucosaminyltransferase mRNA, complete cds. /FEA=mRNA /PROD=I beta 1-6 N-acetylglucosaminyltransferase /DB_XREF=gi:307297 /UG=Hs.934 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme /FL=gb:L19659.1 gb:NM_001491.1 L19659 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) GCNT2 2651 NM_001491 /// NM_145649 /// NM_145655 /// XM_005248997 /// XM_005248999 /// XM_006715052 /// XM_006715053 /// XM_006715054 /// XM_006715055 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010608 // posttranscriptional regulation of gene expression // inferred from mutant phenotype /// 0010608 // posttranscriptional regulation of gene expression // inferred from sequence or structural similarity /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0036438 // maintenance of lens transparency // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008109 // N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008109 // N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity // inferred from mutant phenotype /// 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 211021_s_at AF037194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037194.1 /DEF=Homo sapiens regulator of G protein signaling RGS14-variant, mRNA, complete cds. /FEA=mRNA /PROD=regulator of G protein signaling RGS14-variant /DB_XREF=gi:2708807 /UG=Hs.9347 regulator of G-protein signalling 14 /FL=gb:AF037194.1 AF037194 regulator of G-protein signaling 14 RGS14 10636 NM_006480 /// XM_005265794 /// XM_005265795 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from sequence or structural similarity /// 0031914 // negative regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from sequence or structural similarity /// 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation 211022_s_at BC002521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002521.1 /DEF=Homo sapiens, Similar to alpha thalassemiamental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog), clone MGC:2094, mRNA, complete cds. /FEA=mRNA /PROD=Similar to alpha thalassemiamental retardationsyndrome X-linked (RAD54 (S. cerevisiae) homolog) /DB_XREF=gi:12803396 /UG=Hs.96264 alpha thalassemiamental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog) /FL=gb:BC002521.1 BC002521 alpha thalassemia/mental retardation syndrome X-linked ATRX 546 NM_000489 /// NM_138270 /// NM_138271 /// XM_005262153 /// XM_005262154 /// XM_005262155 /// XM_005262156 /// XM_005262157 /// XM_006724666 /// XM_006724667 /// XM_006724668 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from sequence or structural similarity /// 0032206 // positive regulation of telomere maintenance // inferred from sequence or structural similarity /// 0032508 // DNA duplex unwinding // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072711 // cellular response to hydroxyurea // inferred from sequence or structural similarity /// 1901581 // negative regulation of telomeric RNA transcription from RNA pol II promoter // inferred from sequence or structural similarity 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0031933 // telomeric heterochromatin // inferred from sequence or structural similarity /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 211023_at AL117618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL117618.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K0164 (from clone DKFZp564K0164); complete cds. /FEA=mRNA /GEN=DKFZp564K0164 /PROD=hypothetical protein /DB_XREF=gi:5912196 /UG=Hs.979 pyruvate dehydrogenase (lipoamide) beta /FL=gb:AL117618.1 AL117618 pyruvate dehydrogenase (lipoamide) beta PDHB 5162 NM_000925 /// NM_001173468 /// NR_033384 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation 211024_s_at BC006221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006221.1 /DEF=Homo sapiens, Similar to thyroid transcription factor 1, clone MGC:10523, mRNA, complete cds. /FEA=mRNA /PROD=Similar to thyroid transcription factor 1 /DB_XREF=gi:13623242 /FL=gb:BC006221.1 BC006221 NK2 homeobox 1 NKX2-1 7080 NM_001079668 /// NM_003317 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007492 // endoderm development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009725 // response to hormone // inferred from expression pattern /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021759 // globus pallidus development // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021798 // forebrain dorsal/ventral pattern formation // inferred from electronic annotation /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030324 // lung development // inferred from expression pattern /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from expression pattern /// 0031128 // developmental induction // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0042696 // menarche // inferred from electronic annotation /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from expression pattern /// 0060486 // Clara cell differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 211025_x_at BC006229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006229.1 /DEF=Homo sapiens, cytochrome c oxidase subunit Vb, clone MGC:10622, mRNA, complete cds. /FEA=mRNA /PROD=cytochrome c oxidase subunit Vb /DB_XREF=gi:13623258 /FL=gb:BC006229.1 BC006229 cytochrome c oxidase subunit Vb COX5B 1329 NM_001862 0007585 // respiratory gaseous exchange // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211026_s_at BC006230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006230.1 /DEF=Homo sapiens, lysophospholipase-like, clone MGC:10338, mRNA, complete cds. /FEA=mRNA /PROD=lysophospholipase-like /DB_XREF=gi:13623260 /FL=gb:BC006230.1 BC006230 monoglyceride lipase MGLL 11343 NM_001003794 /// NM_001256585 /// NM_007283 /// XM_005247093 /// XM_005247094 0006629 // lipid metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from sequence or structural similarity /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from sequence or structural similarity /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046464 // acylglycerol catabolic process // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 2000124 // regulation of endocannabinoid signaling pathway // inferred from sequence or structural similarity 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0045202 // synapse // inferred from electronic annotation 0004622 // lysophospholipase activity // traceable author statement /// 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047372 // acylglycerol lipase activity // inferred from sequence or structural similarity /// 0047372 // acylglycerol lipase activity // traceable author statement 211027_s_at BC006231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006231.1 /DEF=Homo sapiens, Similar to inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, clone MGC:11285, mRNA, complete cds. /FEA=mRNA /PROD=Similar to inhibitor of kappa light polypeptidegene enhancer in B-cells, kinase beta /DB_XREF=gi:13623262 /FL=gb:BC006231.1 BC006231 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta IKBKB 3551 NM_001190720 /// NM_001190721 /// NM_001190722 /// NM_001242778 /// NM_001556 /// NR_033818 /// NR_033819 /// NR_040009 /// XM_005273490 /// XM_005273491 /// XM_005273492 /// XM_005273493 /// XM_005273494 /// XM_005273495 /// XM_005273496 /// XM_005273498 /// XM_005273499 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042501 // serine phosphorylation of STAT protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from direct assay 211028_s_at BC006233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006233.1 /DEF=Homo sapiens, ketohexokinase (fructokinase), clone MGC:10370, mRNA, complete cds. /FEA=mRNA /PROD=ketohexokinase (fructokinase) /DB_XREF=gi:13623266 /FL=gb:BC006233.1 BC006233 ketohexokinase (fructokinase) KHK 3795 NM_000221 /// NM_006488 /// XM_005264294 /// XM_005264296 /// XM_005264298 /// XM_006712008 /// XM_006712009 /// XM_006712010 /// XM_006712011 /// XM_006712012 /// XM_006712013 /// XM_006712014 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006001 // fructose catabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004454 // ketohexokinase activity // not recorded /// 0004454 // ketohexokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 211029_x_at BC006245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006245.1 /DEF=Homo sapiens, fibroblast growth factor 18, clone MGC:10529, mRNA, complete cds. /FEA=mRNA /PROD=fibroblast growth factor 18 /DB_XREF=gi:13623288 /FL=gb:BC006245.1 BC006245 fibroblast growth factor 18 FGF18 8817 NM_003862 /// NM_033649 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 211030_s_at BC006252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006252.1 /DEF=Homo sapiens, clone MGC:10619, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10619) /DB_XREF=gi:13623302 /FL=gb:BC006252.1 BC006252 solute carrier family 6 (neurotransmitter transporter), member 6 SLC6A6 6533 NM_001134367 /// NM_001134368 /// NM_003043 /// NR_103507 /// XM_006713307 /// XR_427286 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0015734 // taurine transport // inferred from electronic annotation /// 0015849 // organic acid transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005368 // taurine transmembrane transporter activity // inferred from electronic annotation /// 0005369 // taurine:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0030977 // taurine binding // inferred from electronic annotation 211031_s_at BC006259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006259.1 /DEF=Homo sapiens, clone MGC:11333, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11333) /DB_XREF=gi:13623312 /FL=gb:BC006259.1 BC006259 CAP-GLY domain containing linker protein 2 CLIP2 7461 NM_003388 /// NM_032421 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211032_at BC006264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006264.1 /DEF=Homo sapiens, Similar to KIAA0977 protein, clone MGC:10368, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0977 protein /DB_XREF=gi:13623320 /FL=gb:BC006264.1 BC006264 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 211033_s_at BC006268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006268.1 /DEF=Homo sapiens, peroxisomal biogenesis factor 7, clone MGC:10385, mRNA, complete cds. /FEA=mRNA /PROD=peroxisomal biogenesis factor 7 /DB_XREF=gi:13623327 /FL=gb:BC006268.1 BC006268 peroxisomal biogenesis factor 7 PEX7 5191 NM_000288 /// XM_005267019 /// XM_006715502 /// XM_006715503 0001764 // neuron migration // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008611 // ether lipid biosynthetic process // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005053 // peroxisome matrix targeting signal-2 binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 211034_s_at BC006270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006270.1 /DEF=Homo sapiens, clone MGC:11291, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11291) /DB_XREF=gi:13623331 /FL=gb:BC006270.1 BC006270 HECT domain containing E3 ubiquitin protein ligase 4 HECTD4 283450 NM_001109662 /// NM_173813 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 211036_x_at BC006301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006301.1 /DEF=Homo sapiens, anaphase-promoting complex subunit 5, clone MGC:13295, mRNA, complete cds. /FEA=mRNA /PROD=anaphase-promoting complex subunit 5 /DB_XREF=gi:13623410 /FL=gb:BC006301.1 BC006301 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 /// XM_005253900 /// XM_006719449 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 211037_s_at BC006309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006309.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 5730589L02 gene, clone MGC:13124, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 5730589L02 gene /DB_XREF=gi:13623420 /FL=gb:BC006309.1 BC006309 membrane bound O-acyltransferase domain containing 7 MBOAT7 79143 NM_001146056 /// NM_001146082 /// NM_001146083 /// NM_024298 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 211038_s_at BC006312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006312.1 /DEF=Homo sapiens, Similar to KIAA0445 gene product, clone MGC:12760, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0445 gene product /DB_XREF=gi:13623424 /FL=gb:BC006312.1 BC006312 ciliary rootlet coiled-coil, rootletin pseudogene 2 CROCCP2 84809 NR_026752 0051297 // centrosome organization // inferred from electronic annotation 0035253 // ciliary rootlet // inferred from electronic annotation 211039_at BC006314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006314.1 /DEF=Homo sapiens, Similar to cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), clone MGC:12708, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cholinergic receptor, nicotinic,alpha polypeptide 1 (muscle) /DB_XREF=gi:13623428 /FL=gb:BC006314.1 BC006314 cholinergic receptor, nicotinic, alpha 1 (muscle) CHRNA1 1134 NM_000079 /// NM_001039523 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from mutant phenotype /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from mutant phenotype /// 0007528 // neuromuscular junction development // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0048630 // skeletal muscle tissue growth // inferred from mutant phenotype /// 0050881 // musculoskeletal movement // inferred from mutant phenotype /// 0050905 // neuromuscular process // inferred from mutant phenotype /// 0070050 // neuron cellular homeostasis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // non-traceable author statement 0004889 // acetylcholine-activated cation-selective channel activity // inferred from mutant phenotype /// 0004889 // acetylcholine-activated cation-selective channel activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // traceable author statement /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from sequence or structural similarity /// 0042166 // acetylcholine binding // inferred from sequence or structural similarity 211040_x_at BC006325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006325.1 /DEF=Homo sapiens, G-2 and S-phase expressed 1, clone MGC:12560, mRNA, complete cds. /FEA=mRNA /PROD=G-2 and S-phase expressed 1 /DB_XREF=gi:13623450 /FL=gb:BC006325.1 BC006325 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 211042_x_at BC006329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006329.1 /DEF=Homo sapiens, Similar to melanoma adhesion molecule, clone MGC:12808, mRNA, complete cds. /FEA=mRNA /PROD=Similar to melanoma adhesion molecule /DB_XREF=gi:13623456 /FL=gb:BC006329.1 BC006329 melanoma cell adhesion molecule /// microRNA 6756 MCAM /// MIR6756 4162 /// 102465453 NM_006500 /// NR_106814 /// XM_005271551 /// XM_005271552 /// XM_006718836 /// XM_006718837 /// XM_006718838 0003094 // glomerular filtration // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0061042 // vascular wound healing // inferred from expression pattern 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211043_s_at BC006332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006332.1 /DEF=Homo sapiens, clathrin, light polypeptide (Lcb), clone MGC:12930, mRNA, complete cds. /FEA=mRNA /PROD=clathrin, light polypeptide (Lcb) /DB_XREF=gi:13623458 /FL=gb:BC006332.1 BC006332 clathrin, light chain B CLTB 1212 NM_001834 /// NM_007097 /// NR_045724 /// XM_006714818 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 211044_at BC006333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006333.1 /DEF=Homo sapiens, clone MGC:12564, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12564) /DB_XREF=gi:13623460 /FL=gb:BC006333.1 BC006333 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211045_s_at BC006334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006334.1 /DEF=Homo sapiens, Similar to Eag-related gene member 2, clone MGC:13157, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Eag-related gene member 2 /DB_XREF=gi:13623462 /FL=gb:BC006334.1 BC006334 potassium voltage-gated channel, subfamily H (eag-related), member 6 KCNH6 81033 NM_001278919 /// NM_001278920 /// NM_030779 /// NM_173092 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation 211046_at BC006334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006334.1 /DEF=Homo sapiens, Similar to Eag-related gene member 2, clone MGC:13157, mRNA, complete cds. /FEA=mRNA /PROD=Similar to Eag-related gene member 2 /DB_XREF=gi:13623462 /FL=gb:BC006334.1 BC006334 potassium voltage-gated channel, subfamily H (eag-related), member 6 KCNH6 81033 NM_001278919 /// NM_001278920 /// NM_030779 /// NM_173092 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation 211047_x_at BC006337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006337.1 /DEF=Homo sapiens, clone MGC:12798, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12798) /DB_XREF=gi:13623468 /FL=gb:BC006337.1 BC006337 adaptor-related protein complex 2, sigma 1 subunit AP2S1 1175 NM_004069 /// NM_021575 /// XM_005258499 /// XM_005258500 /// XM_006723004 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030100 // regulation of endocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005215 // transporter activity // non-traceable author statement /// 0008565 // protein transporter activity // non-traceable author statement 211048_s_at BC006344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006344.1 /DEF=Homo sapiens, protein disulfide isomerase related protein (calcium-binding protein, intestinal-related), clone MGC:13117, mRNA, complete cds. /FEA=mRNA /PROD=protein disulfide isomerase related protein(calcium-binding protein, intestinal-related) /DB_XREF=gi:13623480 /FL=gb:BC006344.1 BC006344 protein disulfide isomerase family A, member 4 PDIA4 9601 NM_004911 /// XM_006716185 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded /// 0003756 // protein disulfide isomerase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211049_at BC006356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006356.1 /DEF=Homo sapiens, NCX protein, clone MGC:12870, mRNA, complete cds. /FEA=mRNA /PROD=NCX protein /DB_XREF=gi:13623502 /FL=gb:BC006356.1 BC006356 T-cell leukemia homeobox 2 TLX2 3196 NM_016170 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050774 // negative regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211050_x_at BC006361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006361.1 /DEF=Homo sapiens, clone MGC:13137, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13137) /DB_XREF=gi:13623508 /FL=gb:BC006361.1 BC006361 uncharacterized LOC100134822 /// uncharacterized LOC100288069 /// uncharacterized LOC100996442 /// uncharacterized LOC101927270 /// protein GVQW1-like /// uncharacterized LOC101928670 /// uncharacterized LOC101929540 /// uncharacterized LOC102724409 LOC100134822 /// LOC100288069 /// LOC100996442 /// LOC101927270 /// LOC101928344 /// LOC101928670 /// LOC101929540 /// LOC102724409 100134822 /// 100288069 /// 100996442 /// 101927270 /// 101928344 /// 101928670 /// 101929540 /// 102724409 NR_033908 /// XM_006722953 /// XM_006726770 /// XR_159064 /// XR_242758 /// XR_244045 /// XR_246629 /// XR_252736 /// XR_252843 /// XR_252844 /// XR_253823 /// XR_426564 /// XR_426565 /// XR_426566 /// XR_426567 /// XR_426568 /// XR_426569 /// XR_426570 /// XR_426571 /// XR_426575 /// XR_426576 /// XR_426577 /// XR_426578 /// XR_426579 /// XR_426580 /// XR_426581 /// XR_426582 /// XR_426583 /// XR_426584 /// XR_428627 /// XR_428628 /// XR_428629 /// XR_428630 /// XR_428631 /// XR_428690 /// XR_428691 /// XR_430162 /// XR_430163 /// XR_430164 /// XR_430165 /// XR_430166 /// XR_431953 /// XR_431954 /// XR_432562 /// XR_432563 /// XR_432671 /// XR_432672 /// XR_432673 /// XR_432674 /// XR_432675 /// XR_432676 /// XR_432677 /// XR_432678 /// XR_433519 /// XR_433520 /// XR_433521 /// XR_433522 /// XR_433523 /// XR_433524 /// XR_433525 /// XR_433526 /// XR_433527 211051_s_at BC006363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006363.1 /DEF=Homo sapiens, exostoses (multiple)-like 3, clone MGC:12750, mRNA, complete cds. /FEA=mRNA /PROD=exostoses (multiple)-like 3 /DB_XREF=gi:13623512 /FL=gb:BC006363.1 BC006363 exostosin-like glycosyltransferase 3 EXTL3 2137 NM_001440 /// NR_073468 /// NR_073469 /// XM_006716302 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation 0001888 // glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211052_s_at BC006364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006364.1 /DEF=Homo sapiens, clone MGC:12705, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12705) /DB_XREF=gi:13623514 /FL=gb:BC006364.1 BC006364 tubulin folding cofactor D TBCD 6904 NM_001033052 /// NM_005993 /// XM_005256396 /// XM_005256399 /// XM_005256400 /// XM_005256401 /// XM_005256402 /// XM_005256403 /// XM_005256404 /// XM_005256405 /// XM_006722290 /// XM_006722291 /// XM_006722292 /// XR_430033 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0034333 // adherens junction assembly // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 211053_at BC006367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006367.1 /DEF=Homo sapiens, clone MGC:12878, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12878) /DB_XREF=gi:13623518 /FL=gb:BC006367.1 BC006367 potassium voltage-gated channel, subfamily G, member 1 KCNG1 3755 NM_002237 /// NM_172318 /// XM_006723785 /// XM_006723786 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // non-traceable author statement 211054_at BC006370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006370.1 /DEF=Homo sapiens, Similar to inversin, clone MGC:12888, mRNA, complete cds. /FEA=mRNA /PROD=Similar to inversin /DB_XREF=gi:13623522 /FL=gb:BC006370.1 BC006370 inversin INVS 27130 NM_014425 /// NM_183245 /// NR_051962 /// XM_005251923 /// XM_005251924 /// XR_242585 /// XR_242586 /// XR_428522 0001822 // kidney development // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0060971 // embryonic heart tube left/right pattern formation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 211055_s_at BC006370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006370.1 /DEF=Homo sapiens, Similar to inversin, clone MGC:12888, mRNA, complete cds. /FEA=mRNA /PROD=Similar to inversin /DB_XREF=gi:13623522 /FL=gb:BC006370.1 BC006370 inversin INVS 27130 NM_014425 /// NM_183245 /// NR_051962 /// XM_005251923 /// XM_005251924 /// XR_242585 /// XR_242586 /// XR_428522 0001822 // kidney development // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0060971 // embryonic heart tube left/right pattern formation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 211056_s_at BC006373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006373.1 /DEF=Homo sapiens, clone MGC:12762, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12762) /DB_XREF=gi:13623528 /FL=gb:BC006373.1 BC006373 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) SRD5A1 6715 NM_001047 /// XR_427663 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0007530 // sex determination // non-traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003865 // 3-oxo-5-alpha-steroid 4-dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0047751 // cholestenone 5-alpha-reductase activity // inferred from electronic annotation 211057_at BC006374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006374.1 /DEF=Homo sapiens, Similar to receptor tyrosine kinase-like orphan receptor 1, clone MGC:12687, mRNA, complete cds. /FEA=mRNA /PROD=Similar to receptor tyrosine kinase-like orphanreceptor 1 /DB_XREF=gi:13623530 /FL=gb:BC006374.1 BC006374 receptor tyrosine kinase-like orphan receptor 1 ROR1 4919 NM_001083592 /// NM_005012 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from physical interaction 211058_x_at BC006379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006379.1 /DEF=Homo sapiens, tubulin alpha 1, clone MGC:12832, mRNA, complete cds. /FEA=mRNA /PROD=tubulin alpha 1 /DB_XREF=gi:13623540 /FL=gb:BC006379.1 BC006379 tubulin, alpha 1b TUBA1B 10376 NM_006082 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 211059_s_at BC006381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006381.1 /DEF=Homo sapiens, clone MGC:13287, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13287) /DB_XREF=gi:13623544 /FL=gb:BC006381.1 BC006381 golgin A2 GOLGA2 2801 NM_004486 /// XM_005251930 /// XM_005251931 /// XM_005251932 0000278 // mitotic cell cycle // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 211060_x_at BC006383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006383.1 /DEF=Homo sapiens, clone MGC:12663, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12663) /DB_XREF=gi:13623546 /FL=gb:BC006383.1 BC006383 glycosylphosphatidylinositol anchor attachment 1 GPAA1 8733 NM_003801 0006461 // protein complex assembly // non-traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042765 // GPI-anchor transamidase complex // traceable author statement 0003923 // GPI-anchor transamidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // non-traceable author statement /// 0034235 // GPI anchor binding // inferred from mutant phenotype 211061_s_at BC006390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006390.1 /DEF=Homo sapiens, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, clone MGC:12650, mRNA, complete cds. /FEA=mRNA /PROD=mannosyl (alpha-1,6-)-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:13623554 /FL=gb:BC006390.1 BC006390 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase MGAT2 4247 NM_001015883 /// NM_002408 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008455 // alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211062_s_at BC006393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006393.1 /DEF=Homo sapiens, Similar to carboxypeptidase Z, clone MGC:12742, mRNA, complete cds. /FEA=mRNA /PROD=Similar to carboxypeptidase Z /DB_XREF=gi:13623560 /FL=gb:BC006393.1 BC006393 carboxypeptidase Z /// G protein-coupled receptor 78 CPZ /// GPR78 8532 /// 27201 NM_001014447 /// NM_001014448 /// NM_003652 /// NM_080819 /// NR_045511 0006508 // proteolysis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211063_s_at BC006403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006403.1 /DEF=Homo sapiens, NCK adaptor protein 1, clone MGC:12668, mRNA, complete cds. /FEA=mRNA /PROD=NCK adaptor protein 1 /DB_XREF=gi:13623576 /FL=gb:BC006403.1 BC006403 NCK adaptor protein 1 NCK1 4690 NM_001190796 /// NM_001291999 /// NM_006153 /// XM_005247498 /// XM_006713650 /// XM_006713651 /// XM_006713652 0006417 // regulation of translation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007172 // signal complex assembly // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042110 // T cell activation // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051707 // response to other organism // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019887 // protein kinase regulator activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 211064_at BC006408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006408.1 /DEF=Homo sapiens, Similar to zinc finger protein 254, clone MGC:10544, mRNA, complete cds. /FEA=mRNA /PROD=Similar to zinc finger protein 254 /DB_XREF=gi:13623586 /FL=gb:BC006408.1 BC006408 zinc finger protein 493 ZNF493 284443 NM_001076678 /// NM_145326 /// NM_175910 /// XM_005259864 /// XM_005259865 /// XM_006722730 /// XM_006722731 /// XM_006722732 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 211065_x_at BC006422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006422.1 /DEF=Homo sapiens, clone MGC:12724, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12724) /DB_XREF=gi:13623608 /FL=gb:BC006422.1 BC006422 phosphofructokinase, liver PFKL 5211 NM_001002021 /// NM_002626 /// NR_024108 /// XM_005261135 /// XM_005261136 /// XM_005261137 /// XM_006724011 /// XM_006724012 0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006002 // fructose 6-phosphate metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0003872 // 6-phosphofructokinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation /// 0070061 // fructose binding // inferred from direct assay /// 0070095 // fructose-6-phosphate binding // inferred from direct assay 211066_x_at BC006439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006439.1 /DEF=Homo sapiens, Similar to protocadherin gamma subfamily A, 5, clone MGC:13163, mRNA, complete cds. /FEA=mRNA /PROD=Similar to protocadherin gamma subfamily A, 5 /DB_XREF=gi:13623638 /FL=gb:BC006439.1 BC006439 protocadherin gamma subfamily A, 1 /// protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 2 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 4 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily A, 7 /// protocadherin gamma subfamily A, 8 /// protocadherin gamma subfamily A, 9 /// protocadherin gamma subfamily B, 1 /// protocadherin gamma subfamily B, 2 /// protocadherin gamma subfamily B, 3 /// protocadherin gamma subfamily B, 4 /// protocadherin gamma subfamily B, 5 /// protocadherin gamma subfamily B, 6 /// protocadherin gamma subfamily B, 7 /// protocadherin gamma subfamily C, 3 /// protocadherin gamma subfamily C, 4 /// protocadherin gamma subfamily C, 5 PCDHGA1 /// PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA2 /// PCDHGA3 /// PCDHGA4 /// PCDHGA5 /// PCDHGA6 /// PCDHGA7 /// PCDHGA8 /// PCDHGA9 /// PCDHGB1 /// PCDHGB2 /// PCDHGB3 /// PCDHGB4 /// PCDHGB5 /// PCDHGB6 /// PCDHGB7 /// PCDHGC3 /// PCDHGC4 /// PCDHGC5 5098 /// 8641 /// 9708 /// 26025 /// 56097 /// 56098 /// 56099 /// 56100 /// 56101 /// 56102 /// 56103 /// 56104 /// 56105 /// 56106 /// 56107 /// 56108 /// 56109 /// 56110 /// 56111 /// 56112 /// 56113 /// 56114 NM_002588 /// NM_003735 /// NM_003736 /// NM_014004 /// NM_018912 /// NM_018913 /// NM_018914 /// NM_018915 /// NM_018916 /// NM_018917 /// NM_018918 /// NM_018919 /// NM_018920 /// NM_018921 /// NM_018922 /// NM_018923 /// NM_018924 /// NM_018925 /// NM_018926 /// NM_018927 /// NM_018928 /// NM_018929 /// NM_031993 /// NM_032009 /// NM_032011 /// NM_032053 /// NM_032054 /// NM_032086 /// NM_032087 /// NM_032088 /// NM_032089 /// NM_032090 /// NM_032091 /// NM_032092 /// NM_032094 /// NM_032095 /// NM_032096 /// NM_032097 /// NM_032098 /// NM_032099 /// NM_032100 /// NM_032101 /// NM_032402 /// NM_032403 /// NM_032406 /// NM_032407 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211067_s_at BC006454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006454.1 /DEF=Homo sapiens, growth arrest-specific 7, clone MGC:1348, mRNA, complete cds. /FEA=mRNA /PROD=growth arrest-specific 7 /DB_XREF=gi:13623656 /FL=gb:BC006454.1 BC006454 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 211068_x_at BC006456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006456.1 /DEF=Homo sapiens, clone MGC:1426, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1426) /DB_XREF=gi:13623660 /FL=gb:BC006456.1 BC006456 family with sequence similarity 21, member C /// uncharacterized LOC101930591 FAM21C /// LOC101930591 253725 /// 101930591 NM_001169106 /// NM_001169107 /// NM_015262 /// XR_247516 0006810 // transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211069_s_at BC006462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006462.1 /DEF=Homo sapiens, ubiquitin-like 1 (sentrin), clone MGC:2095, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-like 1 (sentrin) /DB_XREF=gi:13623670 /FL=gb:BC006462.1 BC006462 small ubiquitin-like modifier 1 SUMO1 7341 NM_001005781 /// NM_001005782 /// NM_003352 0006281 // DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030578 // PML body organization // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032880 // regulation of protein localization // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0090204 // protein localization to nuclear pore // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211070_x_at BC006466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006466.1 /DEF=Homo sapiens, clone MGC:2310, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2310) /DB_XREF=gi:13623678 /FL=gb:BC006466.1 BC006466 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) DBI 1622 NM_001079862 /// NM_001079863 /// NM_001178017 /// NM_001178041 /// NM_001178042 /// NM_001178043 /// NM_001282633 /// NM_001282634 /// NM_001282635 /// NM_001282636 /// NM_020548 /// NR_104221 0001942 // hair follicle development // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030156 // benzodiazepine receptor binding // traceable author statement /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 211071_s_at BC006471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006471.1 /DEF=Homo sapiens, ALL1-fused gene from chromosome 1q, clone MGC:4013, mRNA, complete cds. /FEA=mRNA /PROD=ALL1-fused gene from chromosome 1q /DB_XREF=gi:13623686 /FL=gb:BC006471.1 BC006471 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 MLLT11 10962 NM_006818 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051901 // positive regulation of mitochondrial depolarization // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from direct assay 211072_x_at BC006481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006481.1 /DEF=Homo sapiens, tubulin alpha 1, clone MGC:4387, mRNA, complete cds. /FEA=mRNA /PROD=tubulin alpha 1 /DB_XREF=gi:13623706 /FL=gb:BC006481.1 BC006481 tubulin, alpha 1b TUBA1B 10376 NM_006082 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 211073_x_at BC006483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006483.1 /DEF=Homo sapiens, ribosomal protein L3, clone MGC:4393, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L3 /DB_XREF=gi:13623708 /FL=gb:BC006483.1 BC006483 RNA, U86 small nucleolar /// ribosomal protein L3 /// small nucleolar RNA, C/D box 83B RNU86 /// RPL3 /// SNORD83B 6122 /// 116936 /// 116938 NM_000967 /// NM_001033853 /// NR_000026 /// NR_000028 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211074_at AF000381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000381.1 /DEF=Homo sapiens non-functional folate binding protein mRNA, complete cds. /FEA=mRNA /PROD=non-functional folate binding protein /DB_XREF=gi:2565195 /FL=gb:AF000381.1 AF000381 211075_s_at Z25521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25521.1 /DEF=H.sapiens integrin associated protein mRNA, complete CDS,. /FEA=mRNA /PROD=integrin associated protein /DB_XREF=gi:396704 /FL=gb:Z25521.1 Z25521 CD47 molecule CD47 961 NM_001025079 /// NM_001025080 /// NM_001777 /// NM_198793 /// XM_005247908 /// XM_005247909 /// XR_241521 /// XR_241522 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008228 // opsonization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009617 // response to bacterium // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0070053 // thrombospondin receptor activity // inferred from physical interaction 211076_x_at Z22814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z22814.1 /DEF=H.sapiens ORF, complete CDS. /FEA=mRNA /DB_XREF=gi:393697 /FL=gb:Z22814.1 Z22814 atrophin 1 ATN1 1822 NM_001007026 /// NM_001940 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0050827 // toxin receptor binding // inferred from electronic annotation 211077_s_at Z25421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25421.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405720 /FL=gb:Z25421.1 Z25421 tousled-like kinase 1 TLK1 9874 NM_001136554 /// NM_001136555 /// NM_012290 /// XM_005246981 /// XM_006712883 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211078_s_at Z25422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25422.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405722 /FL=gb:Z25422.1 Z25422 serine/threonine kinase 3 STK3 6788 NM_001256312 /// NM_001256313 /// NM_006281 /// XM_005251034 0001841 // neural tube formation // inferred from electronic annotation /// 0003157 // endocardium development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 211079_s_at Z25423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25423.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405724 /FL=gb:Z25423.1 Z25423 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DYRK1A 1859 NM_001396 /// NM_101395 /// NM_130436 /// NM_130437 /// NM_130438 /// XM_005260931 /// XM_005260933 /// XM_006723976 /// XM_006723977 /// XM_006723978 /// XM_006723979 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0090312 // positive regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043621 // protein self-association // inferred from sequence or structural similarity /// 0048156 // tau protein binding // inferred from sequence or structural similarity 211080_s_at Z25425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25425.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405728 /FL=gb:Z25425.1 Z25425 NIMA-related kinase 2 NEK2 4751 NM_001204182 /// NM_001204183 /// NM_002497 /// XM_005273147 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from direct assay /// 0007067 // mitotic nuclear division // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0046602 // regulation of mitotic centrosome separation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051225 // spindle assembly // traceable author statement /// 0051299 // centrosome separation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from electronic annotation /// 1903126 // negative regulation of centriole-centriole cohesion // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211081_s_at Z25426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25426.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405730 /FL=gb:Z25426.1 Z25426 mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 11183 NM_006575 /// NM_198794 /// XM_006720013 /// XM_006720014 0000165 // MAPK cascade // /// 0000185 // activation of MAPKKK activity // /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211082_x_at Z25427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25427.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405732 /FL=gb:Z25427.1 Z25427 MAP/microtubule affinity-regulating kinase 2 MARK2 2011 NM_001039469 /// NM_001163296 /// NM_001163297 /// NM_004954 /// NM_017490 /// XM_006718441 /// XM_006718442 /// XM_006718443 /// XM_006718444 /// XM_006718445 /// XM_006718446 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from mutant phenotype /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from mutant phenotype /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0045180 // basal cortex // inferred from electronic annotation /// 0097427 // microtubule bundle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity 211083_s_at Z25428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25428.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405734 /FL=gb:Z25428.1 Z25428 mitogen-activated protein kinase kinase kinase 13 MAP3K13 9175 NM_001242314 /// NM_001242317 /// NM_004721 /// NR_038322 0000186 // activation of MAPKK activity // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211084_x_at Z25429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25429.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405736 /FL=gb:Z25429.1 Z25429 protein kinase D3 PRKD3 23683 NM_005813 /// XM_005264237 /// XM_005264238 /// XM_006711978 /// XM_006711979 /// XM_006711980 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211085_s_at Z25430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25430.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405738 /FL=gb:Z25430.1 Z25430 serine/threonine kinase 4 STK4 6789 NM_006282 /// XM_005260530 /// XM_005260531 /// XM_005260532 /// XM_005260533 /// XM_006723870 0000902 // cell morphogenesis // inferred from direct assay /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0003157 // endocardium development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060215 // primitive hemopoiesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043539 // protein serine/threonine kinase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay 211086_x_at Z25431 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25431.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405740 /FL=gb:Z25431.1 Z25431 NIMA-related kinase 1 NEK1 4750 NM_001199397 /// NM_001199398 /// NM_001199399 /// NM_001199400 /// NM_012224 /// XM_006714227 /// XM_006714228 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000242 // pericentriolar material // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211087_x_at Z25432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25432.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405742 /FL=gb:Z25432.1 Z25432 mitogen-activated protein kinase 14 MAPK14 1432 NM_001315 /// NM_139012 /// NM_139013 /// NM_139014 /// XM_006714998 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038066 // p38MAPK cascade // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090400 // stress-induced premature senescence // inferred from mutant phenotype /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005623 // cell // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity 211088_s_at Z25433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25433.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405744 /FL=gb:Z25433.1 Z25433 polo-like kinase 4 PLK4 10733 NM_001190799 /// NM_001190801 /// NM_014264 /// XM_005262701 /// XM_006714071 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046601 // positive regulation of centriole replication // inferred from mutant phenotype /// 0060707 // trophoblast giant cell differentiation // inferred from sequence or structural similarity /// 0098535 // de novo centriole assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0098536 // deuterosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 211089_s_at Z25434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25434.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405746 /FL=gb:Z25434.1 Z25434 NIMA-related kinase 3 NEK3 4752 NM_001146099 /// NM_002498 /// NM_152720 /// NR_027415 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211090_s_at Z25435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25435.1 /DEF=H.sapiens protein-serinethreonine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-serinethreonine kinase /DB_XREF=gi:405748 /FL=gb:Z25435.1 Z25435 pre-mRNA processing factor 4B PRPF4B 8899 NM_003913 /// NM_176800 /// XM_006715238 /// XR_241936 /// XR_241940 /// XR_241944 /// XR_241945 /// XR_241947 /// XR_241948 /// XR_241949 /// XR_427838 /// XR_427839 /// XR_427840 /// XR_427841 /// XR_427842 /// XR_427843 /// XR_427844 /// XR_427845 /// XR_427846 /// XR_427847 /// XR_427848 /// XR_427849 /// XR_427850 /// XR_427851 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211091_s_at AF122828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF122828.1 /DEF=Homo sapiens neurofibromatosis type 2 protein isoform Mer151 (NF2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=NF2 /PROD=neurofibromatosis type 2 protein isoform Mer151 /DB_XREF=gi:5730865 /UG=Hs.902 neurofibromin 2 (bilateral acoustic neuroma) /FL=gb:AF122828.1 AF122828 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 211092_s_at AF122827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF122827.1 /DEF=Homo sapiens neurofibromatosis type 2 protein isoform Mer162 (NF2) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=NF2 /PROD=neurofibromatosis type 2 protein isoform Mer162 /DB_XREF=gi:5730863 /UG=Hs.902 neurofibromin 2 (bilateral acoustic neuroma) /FL=gb:AF122827.1 AF122827 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 211093_at U31973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31973.1 /DEF=Human phosphodiesterase A subunit (PDE6C) mRNA, complete cds. /FEA=mRNA /GEN=PDE6C /PROD=phosphodiesterase A subunit /DB_XREF=gi:940230 /UG=Hs.93173 phosphodiesterase 6C, cGMP-specific, cone, alpha prime /FL=gb:NM_006204.1 gb:U31973.1 U31973 phosphodiesterase 6C, cGMP-specific, cone, alpha prime PDE6C 5146 NM_006204 0007165 // signal transduction // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0046549 // retinal cone cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 211094_s_at D12625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D12625.1 /DEF=Human mRNA for NF1 protein isoform (neurofibromin isoform), complete cds. /FEA=mRNA /GEN=NF1 /PROD=NF1 protein isoform /DB_XREF=gi:219939 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:D12625.1 D12625 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 211095_at D12625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D12625.1 /DEF=Human mRNA for NF1 protein isoform (neurofibromin isoform), complete cds. /FEA=mRNA /GEN=NF1 /PROD=NF1 protein isoform /DB_XREF=gi:219939 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:D12625.1 D12625 neurofibromin 1 NF1 4763 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 211096_at BC003111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003111.1 /DEF=Homo sapiens, Similar to pre-B-cell leukemia transcription factor 2, clone MGC:2174, mRNA, complete cds. /FEA=mRNA /PROD=Similar to pre-B-cell leukemia transcriptionfactor 2 /DB_XREF=gi:13111886 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:BC003111.1 BC003111 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211097_s_at BC003111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003111.1 /DEF=Homo sapiens, Similar to pre-B-cell leukemia transcription factor 2, clone MGC:2174, mRNA, complete cds. /FEA=mRNA /PROD=Similar to pre-B-cell leukemia transcriptionfactor 2 /DB_XREF=gi:13111886 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:BC003111.1 BC003111 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211098_x_at AF277194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF277194.1 /DEF=Homo sapiens PNAS-136 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-136 /DB_XREF=gi:12751112 /UG=Hs.93832 putative membrane protein /FL=gb:AF277194.1 AF277194 transmembrane and coiled-coil domains 1 TMCO1 54499 NM_001256164 /// NM_001256165 /// NM_019026 /// NR_045818 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211099_s_at U58837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58837.1 /DEF=Human cGMP-gated cation channel beta subunit (CNCG2) mRNA, complete cds. /FEA=mRNA /GEN=CNCG2 /PROD=cGMP-gated cation channel beta subunit /DB_XREF=gi:1518638 /UG=Hs.93909 cyclic nucleotide gated channel beta 1 /FL=gb:U58837.1 U58837 cyclic nucleotide gated channel beta 1 CNGB1 1258 NM_001135639 /// NM_001286130 /// NM_001297 /// XM_006721134 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017071 // intracellular cyclic nucleotide activated cation channel complex // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 1902495 // transmembrane transporter complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from electronic annotation /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0030552 // cAMP binding // inferred from electronic annotation /// 0030553 // cGMP binding // not recorded /// 0030553 // cGMP binding // inferred from direct assay /// 0043855 // cyclic nucleotide-gated ion channel activity // inferred from electronic annotation 211100_x_at U82278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82278.1 /DEF=Human immunoglobulin-like transcript 1c mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 1c /DB_XREF=gi:1907322 /UG=Hs.94498 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 /FL=gb:U82278.1 gb:AF025531.1 U82278 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 LILRA2 11027 NM_001130917 /// NM_001290270 /// NM_001290271 /// NM_006866 /// XM_005258452 /// XM_005277053 /// XM_005277231 /// XM_005278240 /// XM_006722986 /// XM_006722987 /// XM_006722988 /// XM_006722989 /// XM_006722990 /// XM_006726177 /// XM_006726178 /// XM_006726179 /// XM_006726180 /// XM_006726181 /// XM_006726182 /// XM_006726183 /// XM_006726262 /// XM_006726263 /// XM_006726264 /// XM_006726265 /// XM_006726266 /// XM_006726298 /// XM_006726299 /// XM_006726300 /// XM_006726301 /// XM_006726302 /// XM_006726303 /// XM_006726304 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211101_x_at U82276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82276.1 /DEF=Human immunoglobulin-like transcript 1a mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 1a /DB_XREF=gi:1907318 /UG=Hs.94498 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 /FL=gb:U82276.1 U82276 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 LILRA2 11027 NM_001130917 /// NM_001290270 /// NM_001290271 /// NM_006866 /// XM_005258452 /// XM_005277053 /// XM_005277231 /// XM_005278240 /// XM_006722986 /// XM_006722987 /// XM_006722988 /// XM_006722989 /// XM_006722990 /// XM_006726177 /// XM_006726178 /// XM_006726179 /// XM_006726180 /// XM_006726181 /// XM_006726182 /// XM_006726183 /// XM_006726262 /// XM_006726263 /// XM_006726264 /// XM_006726265 /// XM_006726266 /// XM_006726298 /// XM_006726299 /// XM_006726300 /// XM_006726301 /// XM_006726302 /// XM_006726303 /// XM_006726304 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211102_s_at U82277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82277.1 /DEF=Human immunoglobulin-like transcript 1b mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 1b /DB_XREF=gi:1907320 /UG=Hs.94498 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 /FL=gb:U82277.1 U82277 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 LILRA2 11027 NM_001130917 /// NM_001290270 /// NM_001290271 /// NM_006866 /// XM_005258452 /// XM_005277053 /// XM_005277231 /// XM_005278240 /// XM_006722986 /// XM_006722987 /// XM_006722988 /// XM_006722989 /// XM_006722990 /// XM_006726177 /// XM_006726178 /// XM_006726179 /// XM_006726180 /// XM_006726181 /// XM_006726182 /// XM_006726183 /// XM_006726262 /// XM_006726263 /// XM_006726264 /// XM_006726265 /// XM_006726266 /// XM_006726298 /// XM_006726299 /// XM_006726300 /// XM_006726301 /// XM_006726302 /// XM_006726303 /// XM_006726304 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211103_at U55209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U55209.1 /DEF=Human myosin VIIa transcript 2 mRNA, complete cds. /FEA=mRNA /PROD=myosin VIIa /DB_XREF=gi:1613789 /UG=Hs.95361 myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) /FL=gb:U55209.1 U55209 myosin VIIA MYO7A 4647 NM_000260 /// NM_001127179 /// NM_001127180 /// XM_005274012 /// XM_006718558 /// XM_006718559 /// XM_006718560 /// XM_006718561 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007600 // sensory perception // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0042462 // eye photoreceptor cell development // inferred by curator /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0031477 // myosin VII complex // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from reviewed computational analysis /// 0051015 // actin filament binding // inferred from direct assay 211104_s_at U55209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U55209.1 /DEF=Human myosin VIIa transcript 2 mRNA, complete cds. /FEA=mRNA /PROD=myosin VIIa /DB_XREF=gi:1613789 /UG=Hs.95361 myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) /FL=gb:U55209.1 U55209 myosin VIIA MYO7A 4647 NM_000260 /// NM_001127179 /// NM_001127180 /// XM_005274012 /// XM_006718558 /// XM_006718559 /// XM_006718560 /// XM_006718561 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007600 // sensory perception // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0042462 // eye photoreceptor cell development // inferred by curator /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0031477 // myosin VII complex // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from reviewed computational analysis /// 0051015 // actin filament binding // inferred from direct assay 211105_s_at U80918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U80918.1 /DEF=Homo sapiens transcription factor (NF-ATcC) mRNA, complete cds. /FEA=mRNA /GEN=NF-ATcC /PROD=transcription factor /DB_XREF=gi:4098860 /UG=Hs.96149 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 /FL=gb:U80918.1 U80918 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 4772 NM_001278669 /// NM_001278670 /// NM_001278672 /// NM_001278673 /// NM_001278675 /// NM_006162 /// NM_172387 /// NM_172388 /// NM_172389 /// NM_172390 /// XM_006722477 /// XM_006722478 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from sequence or structural similarity 211106_at AF064804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064804.1 /DEF=Homo sapiens transcription factor SUPT3H (SUPT3H) mRNA, complete cds. /FEA=mRNA /GEN=SUPT3H /PROD=transcription factor SUPT3H /DB_XREF=gi:3283361 /UG=Hs.96757 suppressor of Ty (S.cerevisiae) 3 homolog /FL=gb:AF064804.1 AF064804 suppressor of Ty 3 homolog (S. cerevisiae) SUPT3H 8464 NM_001261823 /// NM_003599 /// NM_181356 /// XM_005249450 /// XM_005249451 /// XM_006715230 /// XR_427837 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211107_s_at AB017332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB017332.1 /DEF=Homo sapiens aik3 mRNA for AuroraIpl1-related kinase 3, complete cds. /FEA=mRNA /GEN=aik3 /PROD=AuroraIpl1-related kinase 3 /DB_XREF=gi:4521232 /UG=Hs.98338 serinethreonine kinase 13 (auroraIPL1-like) /FL=gb:AF054621.1 gb:AB017332.1 AB017332 aurora kinase C AURKC 6795 NM_001015878 /// NM_001015879 /// NM_003160 /// XR_430209 0000910 // cytokinesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016570 // histone modification // traceable author statement /// 0032467 // positive regulation of cytokinesis // traceable author statement /// 0051256 // spindle midzone assembly involved in mitosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0032133 // chromosome passenger complex // traceable author statement /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211108_s_at U31601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31601.1 /DEF=Human tyrosine protein kinase (Jak3B) splice variant mRNA, complete cds. /FEA=mRNA /GEN=Jak3B /PROD=JAK3B /DB_XREF=gi:1039418 /UG=Hs.99877 Janus kinase 3 (a protein tyrosine kinase, leukocyte) /FL=gb:U31601.1 U31601 Janus kinase 3 JAK3 3718 NM_000215 /// XM_005259896 /// XM_006722745 /// XR_430137 0002376 // immune system process // inferred from electronic annotation /// 0002731 // negative regulation of dendritic cell cytokine production // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from sequence or structural similarity /// 0007260 // tyrosine phosphorylation of STAT protein // traceable author statement /// 0007262 // STAT protein import into nucleus // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0032693 // negative regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035771 // interleukin-4-mediated signaling pathway // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043029 // T cell homeostasis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045221 // negative regulation of FasL biosynthetic process // inferred from sequence or structural similarity /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070232 // regulation of T cell apoptotic process // inferred from sequence or structural similarity /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0070669 // response to interleukin-2 // traceable author statement /// 0070670 // response to interleukin-4 // inferred from direct assay /// 0070672 // response to interleukin-15 // traceable author statement /// 0071104 // response to interleukin-9 // traceable author statement /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 211109_at U31601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31601.1 /DEF=Human tyrosine protein kinase (Jak3B) splice variant mRNA, complete cds. /FEA=mRNA /GEN=Jak3B /PROD=JAK3B /DB_XREF=gi:1039418 /UG=Hs.99877 Janus kinase 3 (a protein tyrosine kinase, leukocyte) /FL=gb:U31601.1 U31601 Janus kinase 3 JAK3 3718 NM_000215 /// XM_005259896 /// XM_006722745 /// XR_430137 0002376 // immune system process // inferred from electronic annotation /// 0002731 // negative regulation of dendritic cell cytokine production // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from sequence or structural similarity /// 0007260 // tyrosine phosphorylation of STAT protein // traceable author statement /// 0007262 // STAT protein import into nucleus // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0032693 // negative regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035771 // interleukin-4-mediated signaling pathway // inferred from direct assay /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043029 // T cell homeostasis // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045221 // negative regulation of FasL biosynthetic process // inferred from sequence or structural similarity /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from sequence or structural similarity /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070232 // regulation of T cell apoptotic process // inferred from sequence or structural similarity /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0070669 // response to interleukin-2 // traceable author statement /// 0070670 // response to interleukin-4 // inferred from direct assay /// 0070672 // response to interleukin-15 // traceable author statement /// 0071104 // response to interleukin-9 // traceable author statement /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 211110_s_at AF162704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF162704.1 /DEF=Homo sapiens cell-line MDA-MB-453 androgen receptor mRNA, complete cds. /FEA=mRNA /PROD=androgen receptor /DB_XREF=gi:5639998 /UG=Hs.99915 androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) /FL=gb:M34233.1 gb:AF162704.1 AF162704 androgen receptor AR 367 NM_000044 /// NM_001011645 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003073 // regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007548 // sex differentiation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0019102 // male somatic sex determination // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045720 // negative regulation of integrin biosynthetic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048638 // regulation of developmental growth // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048808 // male genitalia morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060520 // activation of prostate induction by androgen receptor signaling pathway // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0060599 // lateral sprouting involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060685 // regulation of prostatic bud formation // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0060748 // tertiary branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004882 // androgen receptor activity // inferred from direct assay /// 0004882 // androgen receptor activity // inferred from mutant phenotype /// 0004882 // androgen receptor activity // non-traceable author statement /// 0004882 // androgen receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005496 // steroid binding // inferred from electronic annotation /// 0005497 // androgen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // non-traceable author statement /// 0050681 // androgen receptor binding // inferred from electronic annotation /// 0070974 // POU domain binding // inferred from electronic annotation 211111_at AB016902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016902.2 /DEF=Homo sapiens HGC6.3 mRNA, complete cds. /FEA=mRNA /GEN=HGC6.3 /DB_XREF=gi:5030941 /UG=Hs.100469 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 /FL=gb:AB016902.2 AB016902 uncharacterized LOC100128124 HGC6.3 100128124 NM_001129895 /// XM_003846691 211112_at AF054506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054506.1 /DEF=Homo sapiens erythroid K:Cl cotransporter splicing isoform 2 (KCC1) mRNA, complete cds. /FEA=mRNA /GEN=KCC1 /PROD=erythroid K:Cl cotransporter splicing isoform 2 /DB_XREF=gi:3015640 /UG=Hs.10094 solute carrier family 12 (potassiumchloride transporters), member 4 /FL=gb:AF054506.1 AF054506 solute carrier family 12 (potassium/chloride transporter), member 4 SLC12A4 6560 NM_001145961 /// NM_001145962 /// NM_001145963 /// NM_001145964 /// NM_005072 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006884 // cell volume homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 211113_s_at U34919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34919.1 /DEF=Human white homolog (white) mRNA, complete cds. /FEA=mRNA /GEN=white /PROD=white homolog /DB_XREF=gi:1314276 /UG=Hs.10237 ATP-binding cassette, sub-family G (WHITE), member 1 /FL=gb:U34919.1 U34919 ATP-binding cassette, sub-family G (WHITE), member 1 ABCG1 9619 NM_004915 /// NM_016818 /// NM_207174 /// NM_207627 /// NM_207628 /// NM_207629 /// NM_207630 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0009720 // detection of hormone stimulus // non-traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010872 // regulation of cholesterol esterification // inferred from sequence or structural similarity /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0010888 // negative regulation of lipid storage // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0033993 // response to lipid // inferred from direct assay /// 0034374 // low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034436 // glycoprotein transport // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042987 // amyloid precursor protein catabolic process // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055099 // response to high density lipoprotein particle // inferred from electronic annotation /// 1901998 // toxin transport // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // traceable author statement /// 0019534 // toxin transporter activity // inferred from direct assay /// 0034041 // sterol-transporting ATPase activity // inferred from direct assay /// 0034437 // glycoprotein transporter activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // non-traceable author statement 211114_x_at AB037702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB037702.1 /DEF=Homo sapiens SIP1-gamma mRNA for SMN interacting protein 1-gamma, complete cds. /FEA=mRNA /GEN=SIP1-gamma /PROD=SMN interacting protein 1-gamma /DB_XREF=gi:9650994 /UG=Hs.102456 survival of motor neuron protein interacting protein 1 /FL=gb:AB037702.1 AB037702 gem (nuclear organelle) associated protein 2 GEMIN2 8487 NM_001009182 /// NM_001009183 /// NM_003616 0000245 // spliceosomal complex assembly // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211115_x_at AB037703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB037703.1 /DEF=Homo sapiens SIP1-delta mRNA for SMN interacting protein 1-delta, complete cds. /FEA=mRNA /GEN=SIP1-delta /PROD=SMN interacting protein 1-delta /DB_XREF=gi:9650996 /UG=Hs.102456 survival of motor neuron protein interacting protein 1 /FL=gb:AB037703.1 AB037703 gem (nuclear organelle) associated protein 2 GEMIN2 8487 NM_001009182 /// NM_001009183 /// NM_003616 0000245 // spliceosomal complex assembly // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211116_at AF073299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF073299.1 /DEF=Homo sapiens Na+H+ exchanger isoform 2 (NHE2) mRNA, complete cds. /FEA=mRNA /GEN=NHE2 /PROD=Na+H+ exchanger isoform 2 /DB_XREF=gi:5305404 /UG=Hs.103132 solute carrier family 9 (sodiumhydrogen exchanger), isoform 2 /FL=gb:AF073299.1 AF073299 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 SLC9A2 6549 NM_003048 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation 211117_x_at AF124790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF124790.1 /DEF=Homo sapiens estrogen receptor beta2 splice variant mRNA, complete cds. /FEA=mRNA /PROD=estrogen receptor beta2 splice variant /DB_XREF=gi:4894662 /UG=Hs.103504 estrogen receptor 2 (ER beta) /FL=gb:AF124790.1 AF124790 estrogen receptor 2 (ER beta) ESR2 2100 NM_001040275 /// NM_001040276 /// NM_001214902 /// NM_001214903 /// NM_001271876 /// NM_001271877 /// NM_001291712 /// NM_001291723 /// NM_001437 /// NR_073496 /// NR_073497 /// NR_073505 /// XM_006720075 /// XM_006720076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005496 // steroid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030284 // estrogen receptor activity // traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // non-traceable author statement 211118_x_at AF051428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051428.1 /DEF=Homo sapiens estrogen receptor beta2 splice variant mRNA, complete cds. /FEA=mRNA /PROD=estrogen receptor beta2 splice variant /DB_XREF=gi:2961558 /UG=Hs.103504 estrogen receptor 2 (ER beta) /FL=gb:AF051428.1 AF051428 estrogen receptor 2 (ER beta) ESR2 2100 NM_001040275 /// NM_001040276 /// NM_001214902 /// NM_001214903 /// NM_001271876 /// NM_001271877 /// NM_001291712 /// NM_001291723 /// NM_001437 /// NR_073496 /// NR_073497 /// NR_073505 /// XM_006720075 /// XM_006720076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005496 // steroid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030284 // estrogen receptor activity // traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // non-traceable author statement 211119_at AF060555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF060555.1 /DEF=Homo sapiens estrogen receptor beta 3 isoform mRNA, complete cds. /FEA=mRNA /PROD=estrogen receptor beta 3 isoform /DB_XREF=gi:3091285 /UG=Hs.103504 estrogen receptor 2 (ER beta) /FL=gb:AF060555.1 AF060555 estrogen receptor 2 (ER beta) ESR2 2100 NM_001040275 /// NM_001040276 /// NM_001214902 /// NM_001214903 /// NM_001271876 /// NM_001271877 /// NM_001291712 /// NM_001291723 /// NM_001437 /// NR_073496 /// NR_073497 /// NR_073505 /// XM_006720075 /// XM_006720076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005496 // steroid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030284 // estrogen receptor activity // traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // non-traceable author statement 211120_x_at AB006590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006590.1 /DEF=Homo sapiens mRNA for estrogen receptor beta, complete cds. /FEA=mRNA /PROD=estrogen receptor beta /DB_XREF=gi:2911151 /UG=Hs.103504 estrogen receptor 2 (ER beta) /FL=gb:NM_001437.1 gb:AB006590.1 gb:AF051427.1 AB006590 estrogen receptor 2 (ER beta) ESR2 2100 NM_001040275 /// NM_001040276 /// NM_001214902 /// NM_001214903 /// NM_001271876 /// NM_001271877 /// NM_001291712 /// NM_001291723 /// NM_001437 /// NR_073496 /// NR_073497 /// NR_073505 /// XM_006720075 /// XM_006720076 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008628 // hormone-mediated apoptotic signaling pathway // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // non-traceable author statement /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005496 // steroid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030284 // estrogen receptor activity // traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // non-traceable author statement 211121_s_at AF180527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180527.1 /DEF=Homo sapiens p22Dokdel (DOKDEL) mRNA, complete cds. /FEA=mRNA /GEN=DOKDEL /PROD=p22Dokdel /DB_XREF=gi:6606314 /UG=Hs.103854 docking protein 1, 62kD (downstream of tyrosine kinase 1) /FL=gb:AF180527.1 AF180527 docking protein 1, 62kDa (downstream of tyrosine kinase 1) DOK1 1796 NM_001197260 /// NM_001381 /// XM_005264180 /// XM_006711959 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 211122_s_at AF002985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF002985.1 /DEF=Homo sapiens putative alpha chemokine (H174) mRNA, complete cds. /FEA=mRNA /GEN=H174 /PROD=putative alpha chemokine /DB_XREF=gi:2580585 /UG=Hs.103982 small inducible cytokine subfamily B (Cys-X-Cys), member 11 /FL=gb:AF002985.1 AF002985 chemokine (C-X-C motif) ligand 11 CXCL11 6373 NM_005409 0006935 // chemotaxis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010818 // T cell chemotaxis // inferred from mutant phenotype /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 211123_at D87920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87920.1 /DEF=Homo sapiens mRNA for sodium iodide symporter, complete cds. /FEA=mRNA /PROD=sodium iodide symporter /DB_XREF=gi:2887404 /UG=Hs.103983 solute carrier family 5 (sodium iodide symporter), member 5 /FL=gb:U66088.1 gb:D87920.1 gb:NM_000453.1 D87920 solute carrier family 5 (sodium/iodide cotransporter), member 5 SLC5A5 6528 NM_000453 /// XM_005260024 0006590 // thyroid hormone generation // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015705 // iodide transport // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0071371 // cellular response to gonadotropin stimulus // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0008507 // sodium:iodide symporter activity // inferred from electronic annotation /// 0015111 // iodide transmembrane transporter activity // inferred from mutant phenotype /// 0015293 // symporter activity // inferred from electronic annotation 211124_s_at AF119835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119835.1 /DEF=Homo sapiens stem cell factor precursor, mRNA, complete cds. /FEA=mRNA /PROD=stem cell factor precursor /DB_XREF=gi:4530470 /UG=Hs.1048 KIT ligand /FL=gb:AF119835.1 gb:NM_003994.2 AF119835 KIT ligand KITLG 4254 NM_000899 /// NM_003994 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002763 // positive regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0030097 // hemopoiesis // non-traceable author statement /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0070668 // positive regulation of mast cell proliferation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005173 // stem cell factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 211125_x_at AF015730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015730.1 /DEF=Homo sapiens NMDAR1 subunit isoform 3b (hNMDAR1-3b) mRNA, complete cds. /FEA=mRNA /GEN=hNMDAR1-3b /PROD=NMDAR1 subunit isoform 3b /DB_XREF=gi:2343286 /UG=Hs.105 glutamate receptor, ionotropic, N-methyl D-aspartate 1 /FL=gb:AF015730.1 AF015730 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRIN1 2902 NM_000832 /// NM_001185090 /// NM_001185091 /// NM_007327 /// NM_021569 /// XM_005266071 /// XM_005266072 /// XM_005266073 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001967 // suckling behavior // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008355 // olfactory learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010646 // regulation of cell communication // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0018964 // propylene metabolic process // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021586 // pons maturation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071287 // cellular response to manganese ion // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043083 // synaptic cleft // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0016594 // glycine binding // inferred from direct assay /// 0016594 // glycine binding // inferred from mutant phenotype /// 0016595 // glutamate binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 211126_s_at U46006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46006.1 /DEF=Homo sapiens smooth muscle LIM protein (h-SmLIM) mRNA, complete cds. /FEA=mRNA /GEN=h-SmLIM /PROD=smooth muscle LIM protein /DB_XREF=gi:1314358 /UG=Hs.10526 cysteine and glycine-rich protein 2 /FL=gb:U46006.1 U46006 cysteine and glycine-rich protein 2 CSRP2 1466 NM_001321 /// XM_005268678 /// XM_006719258 /// XM_006719259 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211127_x_at AF061194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061194.1 /DEF=Homo sapiens ectodysplasin-A isoform EDA-F (ED1) mRNA, complete cds. /FEA=mRNA /GEN=ED1 /PROD=ectodysplasin-A isoform EDA-F /DB_XREF=gi:3779255 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF061194.1 AF061194 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211128_at AF061191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061191.1 /DEF=Homo sapiens ectodysplasin-A isoform EDA-C (ED1) mRNA, complete cds. /FEA=mRNA /GEN=ED1 /PROD=ectodysplasin-A isoform EDA-C /DB_XREF=gi:3779249 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF061191.1 AF061191 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211129_x_at AF061192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061192.1 /DEF=Homo sapiens ectodysplasin-A isoform EDA-D (ED1) mRNA, complete cds. /FEA=mRNA /GEN=ED1 /PROD=ectodysplasin-A isoform EDA-D /DB_XREF=gi:3779251 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF061192.1 AF061192 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211130_x_at AF061190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061190.1 /DEF=Homo sapiens ectodysplasin-A isoform EDA-B (ED1) mRNA, complete cds. /FEA=mRNA /GEN=ED1 /PROD=ectodysplasin-A isoform EDA-B /DB_XREF=gi:3779247 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF061190.1 AF061190 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211131_s_at AF061193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061193.1 /DEF=Homo sapiens ectodysplasin-A isoform EDA-E (ED1) mRNA, complete cds. /FEA=mRNA /GEN=ED1 /PROD=ectodysplasin-A isoform EDA-E /DB_XREF=gi:3779253 /UG=Hs.105407 ectodermal dysplasia 1, anhidrotic /FL=gb:AF061193.1 AF061193 ectodysplasin A EDA 1896 NM_001005609 /// NM_001005610 /// NM_001005611 /// NM_001005612 /// NM_001005613 /// NM_001005614 /// NM_001399 /// XM_006724630 0001942 // hair follicle development // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0010467 // gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0061153 // trachea gland development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211132_at AF130066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130066.1 /DEF=Homo sapiens clone FLB8124 PRO2179 mRNA, complete cds. /FEA=mRNA /PROD=PRO2179 /DB_XREF=gi:11493438 /UG=Hs.105894 hypothetical protein FLJ21919 /FL=gb:AF130066.1 AF130066 integrator complex subunit 3 INTS3 65123 NM_023015 /// XM_005245459 /// XM_005245461 /// XM_005276735 /// XM_005276737 /// XM_006711490 /// XM_006711491 /// XM_006726204 /// XM_006726205 /// XR_241094 /// XR_254195 0006281 // DNA repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay /// 0070876 // SOSS complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211133_x_at AF009643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009643.1 /DEF=Homo sapiens clone 6 immunoglobulin-like transcript 5 protein mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 5 protein /DB_XREF=gi:2662445 /UG=Hs.105928 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 /FL=gb:AF009643.1 AF009643 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 LILRB3 11025 NM_001081450 /// NM_006864 /// XM_006722983 /// XM_006722984 /// XM_006722985 /// XM_006726175 /// XM_006726176 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211135_x_at AF009644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009644.1 /DEF=Homo sapiens clone 41 immunoglobulin-like transcript 5 protein mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 5 protein /DB_XREF=gi:2662447 /UG=Hs.105928 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 /FL=gb:AF009644.1 AF009644 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 LILRB3 11025 NM_001081450 /// NM_006864 /// XM_006722983 /// XM_006722984 /// XM_006722985 /// XM_006726175 /// XM_006726176 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211136_s_at BC004865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004865.1 /DEF=Homo sapiens, cleft lip and palate associated transmembrane protein 1, clone MGC:10593, mRNA, complete cds. /FEA=mRNA /PROD=cleft lip and palate associated transmembraneprotein 1 /DB_XREF=gi:13436079 /UG=Hs.106671 cleft lip and palate associated transmembrane protein 1 /FL=gb:BC004865.1 BC004865 cleft lip and palate associated transmembrane protein 1 CLPTM1 1209 NM_001199468 /// NM_001282175 /// NM_001282176 /// NM_001294 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211137_s_at AF189723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF189723.2 /DEF=Homo sapiens calcium transport ATPase ATP2C1 (ATP2C1A) mRNA, complete cds. /FEA=mRNA /GEN=ATP2C1A /PROD=calcium transport ATPase ATP2C1 /DB_XREF=gi:6826913 /UG=Hs.106778 ATPase, Ca++ transporting, type 2C, member 1 /FL=gb:AF189723.2 AF189723 ATPase, Ca++ transporting, type 2C, member 1 ATP2C1 27032 NM_001001485 /// NM_001001486 /// NM_001001487 /// NM_001199179 /// NM_001199180 /// NM_001199181 /// NM_001199182 /// NM_001199183 /// NM_001199184 /// NM_001199185 /// NM_014382 /// XM_005247354 /// XM_005247355 /// XM_005247356 /// XM_005247357 /// XM_005247358 /// XM_005247359 /// XM_006713585 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from mutant phenotype /// 0030026 // cellular manganese ion homeostasis // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032468 // Golgi calcium ion homeostasis // inferred from mutant phenotype /// 0032472 // Golgi calcium ion transport // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 0071421 // manganese ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015410 // manganese-transporting ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211138_s_at BC005297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005297.1 /DEF=Homo sapiens, Similar to kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), clone MGC:12362, mRNA, complete cds. /FEA=mRNA /PROD=Similar to kynurenine 3-monooxygenase(kynurenine 3-hydroxylase) /DB_XREF=gi:13529016 /UG=Hs.107318 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) /FL=gb:BC005297.1 BC005297 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) KMO 8564 NM_003679 /// XM_005273337 /// XM_005273338 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from direct assay /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070189 // kynurenine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004502 // kynurenine 3-monooxygenase activity // inferred from direct assay /// 0016174 // NAD(P)H oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 211139_s_at AF045452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF045452.1 /DEF=Homo sapiens cell-line KG1 transcriptional regulatory protein p54 mRNA, complete cds. /FEA=mRNA /PROD=transcriptional regulatory protein p54 /DB_XREF=gi:3282824 /UG=Hs.107474 NGFI-A binding protein 1 (ERG1 binding protein 1) /FL=gb:AF045452.1 AF045452 NGFI-A binding protein 1 (EGR1 binding protein 1) NAB1 4664 NM_005966 /// XM_005246579 /// XM_005246580 /// XM_005246581 /// XM_005246582 /// XM_005246583 /// XM_005246584 /// XM_005246585 /// XM_005246586 /// XM_005246587 /// XM_006712540 0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0008134 // transcription factor binding // inferred from electronic annotation 211140_s_at AF314174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF314174.1 /DEF=Homo sapiens Casp-2L-Pro mRNA, complete cds. /FEA=mRNA /PROD=Casp-2L-Pro /DB_XREF=gi:12642589 /UG=Hs.108131 caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) /FL=gb:AF314174.1 gb:AF314175.1 AF314174 caspase 2, apoptosis-related cysteine peptidase CASP2 835 NM_001224 /// NM_032982 /// NM_032983 0001554 // luteolysis // inferred from electronic annotation /// 0003407 // neural retina development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 211141_s_at AF180474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180474.1 /DEF=Homo sapiens Not3p (NOT3) mRNA, complete cds. /FEA=mRNA /GEN=NOT3 /PROD=Not3p /DB_XREF=gi:6856204 /UG=Hs.108300 CCR4-NOT transcription complex, subunit 3 /FL=gb:AF180474.1 AF180474 CCR4-NOT transcription complex, subunit 3 CNOT3 4849 NM_014516 /// XM_005258956 /// XM_005258957 /// XM_005258958 /// XM_005258959 /// XM_005277076 /// XM_005277077 /// XM_005277078 /// XM_005277079 /// XM_005277266 /// XM_005277267 /// XM_005277268 /// XM_005277269 /// XM_005278279 /// XM_005278280 /// XM_005278281 /// XM_005278282 /// XM_006725771 /// XM_006725772 /// XM_006725773 /// XM_006725774 /// XM_006725872 /// XM_006725873 /// XM_006725874 /// XM_006725875 /// XM_006725960 /// XM_006725961 /// XM_006725962 /// XM_006725963 /// XM_006726059 /// XM_006726060 /// XM_006726061 /// XM_006726062 /// XM_006726160 /// XM_006726161 /// XM_006726162 /// XM_006726163 /// XM_006726197 /// XM_006726198 /// XM_006726199 /// XM_006726200 /// XR_243935 /// XR_243936 /// XR_254258 /// XR_254259 /// XR_254309 /// XR_254310 /// XR_254515 /// XR_254516 /// XR_430951 /// XR_430952 /// XR_430984 /// XR_430985 /// XR_431004 /// XR_431005 /// XR_431023 /// XR_431024 /// XR_431054 /// XR_431055 /// XR_431065 /// XR_431066 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211142_x_at M38056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M38056.1 /DEF=Human lymphocyte antigen mRNA, complete cds. /FEA=mRNA /GEN=HLA /PROD=lymphocyte antigen /DB_XREF=gi:184159 /UG=Hs.11135 major histocompatibility complex, class II, DN alpha /FL=gb:M38056.1 M38056 major histocompatibility complex, class II, DO alpha HLA-DOA 3111 NM_002119 /// XM_005249047 /// XM_005272804 /// XM_005274951 /// XM_005275106 /// XM_005275243 /// XM_005275383 /// XM_005275540 /// XM_006715076 /// XM_006725483 /// XM_006725697 /// XM_006725815 /// XM_006725906 /// XM_006725996 /// XM_006726086 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002587 // negative regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement 211143_x_at D49728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D49728.1 /DEF=Human NAK1 mRNA for DNA binding protein, complete cds. /FEA=mRNA /GEN=NAK1 /PROD=DNA binding protein /DB_XREF=gi:1813881 /UG=Hs.1119 nuclear receptor subfamily 4, group A, member 1 /FL=gb:D49728.1 D49728 nuclear receptor subfamily 4, group A, member 1 NR4A1 3164 NM_001202233 /// NM_001202234 /// NM_002135 /// NM_173157 /// NM_173158 /// XM_005268822 /// XM_005268823 /// XM_005268824 /// XM_006719363 /// XM_006719364 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211144_x_at M30894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30894.1 /DEF=Human T-cell receptor Ti rearranged gamma-chain mRNA V-J-C region, complete cds. /FEA=mRNA /GEN=CD3G /DB_XREF=gi:339406 /UG=Hs.112259 T cell receptor gamma locus /FL=gb:M30894.1 M30894 TCR gamma alternate reading frame protein /// T cell receptor gamma constant 2 /// T cell receptor gamma variable 9 TARP /// TRGC2 /// TRGV9 6967 /// 6983 /// 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 211145_x_at M12350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M12350.1 /DEF=Human leukocytic interferon alpha-F (IFN-alpha-F) mRNA, complete cds. /FEA=mRNA /GEN=IFNA /DB_XREF=gi:184598 /UG=Hs.113211 interferon, alpha 21 /FL=gb:M12350.1 gb:M28586.1 gb:NM_002175.1 M12350 interferon, alpha 21 IFNA21 3452 NM_002175 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 211146_at U96291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96291.1 /DEF=Homo sapiens Ig kappa light chain variable region (VkII-A23) mRNA, complete cds. /FEA=mRNA /GEN=VkII-A23 /PROD=Ig kappa light chain variable region /DB_XREF=gi:2345027 /UG=Hs.113273 Homo sapiens Ig kappa light chain variable region (VkII-A23) mRNA, complete cds /FL=gb:U96291.1 U96291 immunoglobulin kappa constant IGKC 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 211147_s_at AF065385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF065385.1 /DEF=Homo sapiens purinoceptor P2X6 (P2X6) mRNA, complete cds. /FEA=mRNA /GEN=P2X6 /PROD=purinoceptor P2X6 /DB_XREF=gi:6469323 /UG=Hs.113275 purinergic receptor P2X-like 1, orphan receptor /FL=gb:AF065385.1 AF065385 purinergic receptor P2X, ligand-gated ion channel, 6 P2RX6 9127 NM_001159554 /// NM_005446 /// XM_005261819 /// XM_006724369 /// XM_006724370 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // not recorded /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005639 // integral component of nuclear inner membrane // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0015267 // channel activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 211148_s_at AF187858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF187858.1 /DEF=Homo sapiens angiopoietin-2 isoform-1 mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=angiopoietin-2 isoform-1 /DB_XREF=gi:8570646 /UG=Hs.115181 angiopoietin 2 /FL=gb:AF187858.1 AF187858 angiopoietin 2 ANGPT2 285 NM_001118887 /// NM_001118888 /// NM_001147 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0050928 // negative regulation of positive chemotaxis // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072012 // glomerulus vasculature development // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211149_at AF000994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000994.1 /DEF=Homo sapiens ubiquitous TPR motif, Y isoform (UTY) mRNA, alternative transcript 3, complete cds. /FEA=mRNA /GEN=UTY /PROD=ubiquitous TPR motif, Y isoform /DB_XREF=gi:2580573 /UG=Hs.115277 ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome /FL=gb:AF000994.1 AF000994 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked UTY 7404 NM_001258249 /// NM_001258250 /// NM_001258251 /// NM_001258252 /// NM_001258253 /// NM_001258254 /// NM_001258255 /// NM_001258256 /// NM_001258257 /// NM_001258258 /// NM_001258259 /// NM_001258260 /// NM_001258261 /// NM_001258262 /// NM_001258263 /// NM_001258264 /// NM_001258265 /// NM_001258266 /// NM_001258267 /// NM_001258268 /// NM_001258269 /// NM_001258270 /// NM_007125 /// NM_182659 /// NM_182660 /// NR_047596 /// NR_047597 /// NR_047598 /// NR_047599 /// NR_047600 /// NR_047601 /// NR_047602 /// NR_047603 /// NR_047604 /// NR_047605 /// NR_047606 /// NR_047607 /// NR_047608 /// NR_047609 /// NR_047610 /// NR_047611 /// NR_047612 /// NR_047613 /// NR_047614 /// NR_047615 /// NR_047616 /// NR_047617 /// NR_047618 /// NR_047619 /// NR_047620 /// NR_047621 /// NR_047622 /// NR_047623 /// NR_047624 /// NR_047625 /// NR_047626 /// NR_047627 /// NR_047628 /// NR_047629 /// NR_047630 /// NR_047631 /// NR_047632 /// NR_047633 /// NR_047634 /// NR_047635 /// NR_047636 /// NR_047637 /// NR_047638 /// NR_047639 /// NR_047640 /// NR_047641 /// NR_047642 /// NR_047643 /// NR_047644 /// NR_047645 /// NR_047646 /// NR_047647 /// XM_005262518 /// XM_006724875 /// XM_006724876 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031935 // regulation of chromatin silencing // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from electronic annotation /// 0086003 // cardiac muscle cell contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from electronic annotation 211150_s_at J03866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J03866.1 /DEF=Homo sapiens M2 mitochondrial autoantigen dihydrolipoamide acetyltransferase mRNA, complete cds. /FEA=mRNA /PROD=dihydrolipoamide acetyltransferase /DB_XREF=gi:619443 /UG=Hs.115285 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) /FL=gb:J03866.1 J03866 dihydrolipoamide S-acetyltransferase DLAT 1737 NM_001931 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006085 // acetyl-CoA biosynthetic process // non-traceable author statement /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // non-traceable author statement /// 0045254 // pyruvate dehydrogenase complex // inferred from electronic annotation 0004742 // dihydrolipoyllysine-residue acetyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 211151_x_at AF185611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF185611.1 /DEF=Homo sapiens growth hormone variant (GHV) mRNA, complete cds. /FEA=mRNA /GEN=GHV /PROD=growth hormone variant /DB_XREF=gi:9963798 /UG=Hs.115352 growth hormone 1 /FL=gb:AF185611.1 AF185611 growth hormone 1 GH1 2688 NM_000515 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211152_s_at AF184911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF184911.1 /DEF=Homo sapiens serine protease (OMI) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=OMI /PROD=serine protease /DB_XREF=gi:10121319 /UG=Hs.115721 HtrA-like serine protease /FL=gb:AF184911.1 AF184911 HtrA serine peptidase 2 HTRA2 27429 NM_013247 /// NM_145074 /// XM_005264266 0006508 // proteolysis // inferred from mutant phenotype /// 0006508 // proteolysis // traceable author statement /// 0006672 // ceramide metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0009635 // response to herbicide // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016540 // protein autoprocessing // traceable author statement /// 0019742 // pentacyclic triterpenoid metabolic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001269 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005739 // mitochondrion // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 211153_s_at AB037599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB037599.1 /DEF=Homo sapiens mRNA for sODFTRANCE, complete cds. /FEA=mRNA /GEN=sOdftrance /PROD=sODFTRANCE /DB_XREF=gi:6863047 /UG=Hs.115770 tumor necrosis factor (ligand) superfamily, member 11 /FL=gb:AB037599.1 AB037599 tumor necrosis factor (ligand) superfamily, member 11 TNFSF11 8600 NM_003701 /// NM_033012 0001503 // ossification // inferred from electronic annotation /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0030316 // osteoclast differentiation // non-traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045453 // bone resorption // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045780 // positive regulation of bone resorption // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051466 // positive regulation of corticotropin-releasing hormone secretion // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071812 // positive regulation of fever generation by positive regulation of prostaglandin secretion // inferred from sequence or structural similarity /// 0071847 // TNFSF11-mediated signaling pathway // inferred from direct assay /// 0071848 // positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling // inferred from direct assay /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // non-traceable author statement /// 0005164 // tumor necrosis factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred by curator 211154_at D32047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32047.1 /DEF=Homo sapiens mRNA for thrombopoietin, complete cds. /FEA=mRNA /PROD=thrombopoietin /DB_XREF=gi:2351117 /UG=Hs.1166 thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) /FL=gb:D32047.1 D32047 thrombopoietin THPO 7066 NM_000460 /// NM_001177597 /// NM_001177598 /// NM_001289997 /// NM_001289998 /// NM_001290003 /// NM_001290022 /// NM_001290026 /// NM_001290027 /// NM_001290028 /// NM_199228 /// NM_199356 /// XM_005247737 /// XM_006713738 /// XM_006713739 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0038163 // thrombopoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // traceable author statement 211155_s_at D32047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32047.1 /DEF=Homo sapiens mRNA for thrombopoietin, complete cds. /FEA=mRNA /PROD=thrombopoietin /DB_XREF=gi:2351117 /UG=Hs.1166 thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) /FL=gb:D32047.1 D32047 thrombopoietin THPO 7066 NM_000460 /// NM_001177597 /// NM_001177598 /// NM_001289997 /// NM_001289998 /// NM_001290003 /// NM_001290022 /// NM_001290026 /// NM_001290027 /// NM_001290028 /// NM_199228 /// NM_199356 /// XM_005247737 /// XM_006713738 /// XM_006713739 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0038163 // thrombopoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // traceable author statement 211156_at AF115544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF115544.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor p12 (p16INK4a) mRNA, alternatively spliced form, complete cds. /FEA=mRNA /GEN=p16INK4a /PROD=cyclin-dependent kinase inhibitor p12 /DB_XREF=gi:4206166 /UG=Hs.1174 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) /FL=gb:AF115544.1 AF115544 cyclin-dependent kinase inhibitor 2A CDKN2A 1029 NM_000077 /// NM_001195132 /// NM_058195 /// NM_058196 /// NM_058197 /// XM_005251343 0000075 // cell cycle checkpoint // inferred from mutant phenotype /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001953 // negative regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from mutant phenotype /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0031648 // protein destabilization // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from mutant phenotype /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from sequence or structural similarity /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0090398 // cellular senescence // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype /// 1902510 // regulation of apoptotic DNA fragmentation // inferred from mutant phenotype /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0055105 // ubiquitin-protein transferase inhibitor activity // inferred from sequence or structural similarity /// 0097371 // MDM2/MDM4 family protein binding // inferred from physical interaction 211157_at AF119878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119878.1 /DEF=Homo sapiens PRO2353 mRNA, complete cds. /FEA=mRNA /PROD=PRO2353 /DB_XREF=gi:7770192 /UG=Hs.117612 hypothetical protein PRO2353 /FL=gb:AF119878.1 AF119878 211159_s_at AB000635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000635.1 /DEF=Homo sapiens mRNA for protein phosphatase 2A delta (B) regulatory subunit, delta3 isoform, complete cds. /FEA=mRNA /PROD=protein phosphatase 2A delta (B) regulatorysubunit, delta3 isoform /DB_XREF=gi:2189948 /UG=Hs.118244 protein phosphatase 2, regulatory subunit B (B56), delta isoform /FL=gb:AB000635.1 AB000635 protein phosphatase 2, regulatory subunit B', delta PPP2R5D 5528 NM_001270476 /// NM_006245 /// NM_180976 /// NM_180977 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 211160_x_at M95178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M95178.1 /DEF=Human non-muscle alpha-actinin mRNA, complete cds. /FEA=mRNA /GEN=ACTN1 /PROD=alpha-actinin /DB_XREF=gi:178051 /UG=Hs.119000 actinin, alpha 1 /FL=gb:M95178.1 M95178 actinin, alpha 1 ACTN1 87 NM_001102 /// NM_001130004 /// NM_001130005 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0042995 // cell projection // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 211161_s_at AF130082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130082.1 /DEF=Homo sapiens clone FLC1492 PRO3121 mRNA, complete cds. /FEA=mRNA /PROD=PRO3121 /DB_XREF=gi:11493468 /UG=Hs.119571 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) /FL=gb:AF130082.1 AF130082 collagen, type III, alpha 1 COL3A1 1281 NM_000090 0001501 // skeletal system development // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // non-traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005586 // collagen type III trimer // inferred from mutant phenotype /// 0005586 // collagen type III trimer // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement 0005178 // integrin binding // inferred from mutant phenotype /// 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 211162_x_at AF116616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116616.1 /DEF=Homo sapiens PRO0998 mRNA, complete cds. /FEA=mRNA /PROD=PRO0998 /DB_XREF=gi:7959734 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF116616.1 AF116616 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation 211163_s_at AF012536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF012536.1 /DEF=Homo sapiens decoy receptor 1 (DcR1) mRNA, complete cds. /FEA=mRNA /GEN=DcR1 /PROD=decoy receptor 1 /DB_XREF=gi:2338421 /UG=Hs.119684 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain /FL=gb:AF012536.1 AF012536 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain TNFRSF10C 8794 NM_003841 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045569 // TRAIL binding // inferred from electronic annotation 211164_at AF213460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF213460.1 /DEF=Homo sapiens ephrin receptor EPHA3 secreted form (EPHA3) mRNA, complete cds. /FEA=mRNA /GEN=EPHA3 /PROD=ephrin receptor EPHA3 secreted form /DB_XREF=gi:12003436 /UG=Hs.123642 EphA3 /FL=gb:AF213460.1 AF213460 EPH receptor A3 EPHA3 2042 NM_005233 /// NM_182644 /// XM_005264715 /// XM_005264716 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity /// 0097156 // fasciculation of motor neuron axon // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211165_x_at D31661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D31661.1 /DEF=Human mRNA for tyrosine kinase, complete cds. /FEA=mRNA /GEN=ERK /PROD=tyrosine kinase precursor /DB_XREF=gi:495677 /UG=Hs.125124 EphB2 /FL=gb:D31661.1 D31661 EPH receptor B2 EPHB2 2048 NM_004442 /// NM_017449 /// XM_006710441 /// XM_006710442 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0007612 // learning // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211166_at AF155097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155097.1 /DEF=Homo sapiens NY-REN-7 antigen mRNA, complete cds. /FEA=mRNA /PROD=NY-REN-7 antigen /DB_XREF=gi:5360088 /UG=Hs.126779 KIAA0752 protein /FL=gb:AF155097.1 AF155097 family with sequence similarity 153, member A FAM153A 285596 NM_173663 /// XM_005265889 /// XM_006714841 /// XM_006714842 /// XM_006714843 /// XM_006714844 /// XM_006714845 /// XM_006714846 /// XM_006714847 /// XM_006714848 /// XM_006714849 /// XM_006714850 /// XM_006714851 /// XM_006714852 /// XM_006714853 /// XM_006714854 /// XR_425938 /// XR_425939 211167_s_at M69051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M69051.1 /DEF=Human liver glucokinase (ATP:D-hexose 6-phosphotransferase) mRNA, complete cds. /FEA=mRNA /GEN=GLK /PROD=glucokinase /DB_XREF=gi:183226 /UG=Hs.1270 glucokinase (hexokinase 4, maturity onset diabetes of the young 2) /FL=gb:M69051.1 M69051 glucokinase (hexokinase 4) GCK 2645 NM_000162 /// NM_033507 /// NM_033508 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006110 // regulation of glycolytic process // non-traceable author statement /// 0006739 // NADP metabolic process // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043266 // regulation of potassium ion transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044320 // cellular response to leptin stimulus // inferred from sequence or structural similarity /// 0045721 // negative regulation of gluconeogenesis // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation /// 0051594 // detection of glucose // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070509 // calcium ion import // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // inferred from direct assay /// 0004396 // hexokinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005536 // glucose binding // inferred from direct assay /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation 211168_s_at D86988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86988.1 /DEF=Human mRNA for KIAA0221 gene, complete cds. /FEA=mRNA /GEN=KIAA0221 /PROD=KIAA0221 /DB_XREF=gi:1944406 /UG=Hs.12719 regulator of nonsense transcripts 1 /FL=gb:D86988.1 D86988 UPF1 regulator of nonsense transcripts homolog (yeast) UPF1 5976 NM_002911 /// XM_005260015 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from direct assay /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006449 // regulation of translational termination // inferred from mutant phenotype /// 0006449 // regulation of translational termination // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0044530 // supraspliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211169_s_at AF024579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF024579.1 /DEF=Homo sapiens protein phosphatase type-1 glycogen targeting subunit (PPP1R3) mRNA, complete cds. /FEA=mRNA /GEN=PPP1R3 /PROD=protein phosphatase type-1 glycogen targetingsubunit /DB_XREF=gi:2739041 /UG=Hs.127614 protein phosphatase 1, regulatory (inhibitor) subunit 3 (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle) /FL=gb:AF024579.1 AF024579 protein phosphatase 1, regulatory subunit 3A PPP1R3A 5506 NM_002711 /// XM_005250473 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211170_s_at AF127480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF127480.1 /DEF=Homo sapiens 3,5-cyclic nucleotide phosphodiesterase 10A2 (PDE10A) mRNA, splice variant 2, partial cds. /FEA=mRNA /GEN=PDE10A /PROD=3,5-cyclic nucleotide phosphodiesterase 10A2 /DB_XREF=gi:4894716 /UG=Hs.128291 phosphodiesterase 10A /FL=gb:AB026816.1 AF127480 phosphodiesterase 10A PDE10A 10846 NM_001130690 /// NM_006661 /// NR_045597 /// XM_006715321 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from direct assay /// 0030552 // cAMP binding // non-traceable author statement /// 0030553 // cGMP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 211171_s_at AB026816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB026816.1 /DEF=Homo sapiens PDE10A2 mRNA for 3,5-cyclic nucleotide phosphodiesterase 10A2, complete cds. /FEA=mRNA /GEN=PDE10A2 /PROD=3,5-cyclic nucleotide phosphodiesterase 10A2 /DB_XREF=gi:5902441 /UG=Hs.128291 phosphodiesterase 10A /FL=gb:AB026816.1 AB026816 phosphodiesterase 10A PDE10A 10846 NM_001130690 /// NM_006661 /// NR_045597 /// XM_006715321 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from direct assay /// 0030552 // cAMP binding // non-traceable author statement /// 0030553 // cGMP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 211172_x_at AF161075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF161075.1 /DEF=Homo sapiens A-kinase anchoring protein 18 beta mRNA, complete cds. /FEA=mRNA /PROD=A-kinase anchoring protein 18 beta /DB_XREF=gi:6716556 /UG=Hs.12835 A kinase (PRKA) anchor protein 7 /FL=gb:AF161075.1 AF161075 A kinase (PRKA) anchor protein 7 AKAP7 9465 NM_004842 /// NM_016377 /// NM_138633 /// XM_005267228 /// XM_005267229 /// XM_006715614 /// XR_427979 0001508 // action potential // inferred by curator /// 0006811 // ion transport // traceable author statement /// 0008104 // protein localization // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902261 // positive regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay /// 0051018 // protein kinase A binding // traceable author statement 211173_at D85606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D85606 /DEF=Homo sapiens gene for cholecystokinin type-A receptor, complete cds /FEA=mRNA /DB_XREF=gi:7008026 /UG=Hs.129 cholecystokinin A receptor /FL=gb:L13605.1 gb:L19315.1 gb:NM_000730.1 D85606 cholecystokinin A receptor CCKAR 886 NM_000730 0001764 // neuron migration // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0038188 // cholecystokinin signaling pathway // inferred from electronic annotation /// 0038188 // cholecystokinin signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004951 // cholecystokinin receptor activity // inferred from electronic annotation 211174_s_at L13605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L13605.1 /DEF=Human cholecystokinin A receptor mRNA, complete cds. /FEA=mRNA /PROD=cholecystokinin A receptor /DB_XREF=gi:306490 /UG=Hs.129 cholecystokinin A receptor /FL=gb:L13605.1 gb:L19315.1 gb:NM_000730.1 L13605 cholecystokinin A receptor CCKAR 886 NM_000730 0001764 // neuron migration // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0038188 // cholecystokinin signaling pathway // inferred from electronic annotation /// 0038188 // cholecystokinin signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004951 // cholecystokinin receptor activity // inferred from electronic annotation 211175_at U92642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U92642.1 /DEF=Human high-affinity lysophosphatidic acid receptor homolog mRNA, complete cds. /FEA=mRNA /PROD=high-affinity lysophosphatidic acid receptorhomolog /DB_XREF=gi:2735350 /UG=Hs.129701 G protein-coupled receptor 45 /FL=gb:U92642.1 gb:NM_007227.1 U92642 G protein-coupled receptor 45 GPR45 11250 NM_007227 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 211176_s_at AB008913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB008913.1 /DEF=Homo sapiens mRNA for Pax-4, complete cds. /FEA=mRNA /PROD=Pax-4 /DB_XREF=gi:2809074 /UG=Hs.129706 paired box gene 4 /FL=gb:AB008913.1 AB008913 paired box 4 PAX4 5078 NM_006193 /// XM_005250397 /// XR_242243 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211177_s_at AB019695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB019695.1 /DEF=Homo sapiens mRNA for thioredoxin reductase II beta, complete cds. /FEA=mRNA /PROD=thioredoxin reductase II beta /DB_XREF=gi:4827178 /UG=Hs.12971 thioredoxin reductase beta /FL=gb:AB019695.1 AB019695 thioredoxin reductase 2 TXNRD2 10587 NM_001282512 /// NM_006440 /// NM_145747 /// NM_145748 0000305 // response to oxygen radical // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0004791 // thioredoxin-disulfide reductase activity // not recorded /// 0004791 // thioredoxin-disulfide reductase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 211178_s_at AF038602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF038602.1 /DEF=Homo sapiens CD2 binding protein 1 short form mRNA, complete cds. /FEA=mRNA /PROD=CD2 binding protein 1 short form /DB_XREF=gi:2921548 /UG=Hs.129758 proline-serine-threonine phosphatase interacting protein 1 /FL=gb:AF038602.1 AF038602 proline-serine-threonine phosphatase interacting protein 1 PSTPIP1 9051 NM_003978 /// XM_006720736 /// XM_006720737 /// XM_006720738 /// XM_006720739 /// XR_429473 /// XR_429474 0002376 // immune system process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001931 // uropod // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005826 // actomyosin contractile ring // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation 211179_at AY004251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY004251.2 /DEF=Homo sapiens AML1AMP19 fusion protein (AML1AMP19 fusion) mRNA, complete cds. /FEA=mRNA /GEN=AML1AMP19 fusion /PROD=AML1AMP19 fusion protein /DB_XREF=gi:10765094 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:AY004251.2 AY004251 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 211180_x_at D89788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89788.1 /DEF=Homo sapiens mRNA for AML1, complete cds. /FEA=mRNA /GEN=AML1 delta-N /PROD=AML1 /DB_XREF=gi:1752816 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:D89788.1 gb:D89789.1 gb:D89790.1 D89788 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 211181_x_at AF312386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312386.1 /DEF=Homo sapiens clone L4 AML1AMP19 fusion protein (AML1AMP19 fusion) mRNA, complete cds. /FEA=mRNA /GEN=AML1AMP19 fusion /PROD=AML1AMP19 fusion protein /DB_XREF=gi:12082788 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:AF312386.1 AF312386 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0051101 // regulation of DNA binding // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060039 // pericardium development // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from mutant phenotype /// 0071108 // protein K48-linked deubiquitination // inferred from mutant phenotype /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 0072001 // renal system development // inferred from electronic annotation /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008233 // peptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032183 // SUMO binding // inferred from direct assay /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 211182_x_at AF312387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312387.1 /DEF=Homo sapiens clone L2 AML1AMP19 fusion protein (AML1AMP19 fusion) mRNA, complete cds. /FEA=mRNA /GEN=AML1AMP19 fusion /PROD=AML1AMP19 fusion protein /DB_XREF=gi:12082790 /UG=Hs.129914 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) /FL=gb:AF312387.1 AF312387 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 211184_s_at AB006955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006955.1 /DEF=Homo sapiens mRNA for AIE-75, complete cds. /FEA=mRNA /GEN=aie-75 /PROD=AIE-75 /DB_XREF=gi:5152287 /UG=Hs.132945 PDZ-73 protein /FL=gb:AB006955.1 AB006955 Usher syndrome 1C (autosomal recessive, severe) USH1C 10083 NM_005709 /// NM_153676 /// XM_005252725 /// XM_006718119 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0030046 // parallel actin filament bundle assembly // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // traceable author statement /// 0045177 // apical part of cell // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 211185_s_at AF130099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130099.1 /DEF=Homo sapiens clone FLC1464 PRO3102 mRNA, complete cds. /FEA=mRNA /PROD=PRO3102 /DB_XREF=gi:11493501 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF130099.1 AF130099 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211186_s_at BC002695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002695.1 /DEF=Homo sapiens, Similar to KIAA1048 protein, clone MGC:3535, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA1048 protein /DB_XREF=gi:12803718 /UG=Hs.135941 KIAA1048 protein /FL=gb:BC002695.1 BC002695 AP2 associated kinase 1 AAK1 22848 NM_014911 0006468 // protein phosphorylation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 211187_at AF118079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118079.1 /DEF=Homo sapiens PRO1854 mRNA, complete cds. /FEA=mRNA /PROD=PRO1854 /DB_XREF=gi:6650803 /UG=Hs.136570 PRO1854 protein /FL=gb:AF118079.1 AF118079 211188_at U96627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U96627.1 /DEF=Homo sapiens CD84 mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=CD84 /DB_XREF=gi:4100318 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:U96627.1 U96627 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211189_x_at AF054816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054816.1 /DEF=Homo sapiens leukocyte differentiation antigen CD84 isoform CD84a (CD84) mRNA, complete cds. /FEA=mRNA /GEN=CD84 /PROD=leukocyte differentiation antigen CD84 isoformCD84a /DB_XREF=gi:6650107 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:AF054816.1 AF054816 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211190_x_at AF054817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054817.1 /DEF=Homo sapiens leukocyte differentiation antigen CD84 isoform CD84d (CD84) mRNA, complete cds. /FEA=mRNA /GEN=CD84 /PROD=leukocyte differentiation antigen CD84 isoformCD84d /DB_XREF=gi:6650109 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:AF054817.1 AF054817 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211191_at AF054818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054818.1 /DEF=Homo sapiens leukocyte differentiation antigen CD84 isoform CD84s (CD84) mRNA, complete cds. /FEA=mRNA /GEN=CD84 /PROD=leukocyte differentiation antigen CD84 isoformCD84s /DB_XREF=gi:6650111 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:AF054818.1 AF054818 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211192_s_at AF054818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054818.1 /DEF=Homo sapiens leukocyte differentiation antigen CD84 isoform CD84s (CD84) mRNA, complete cds. /FEA=mRNA /GEN=CD84 /PROD=leukocyte differentiation antigen CD84 isoformCD84s /DB_XREF=gi:6650111 /UG=Hs.137548 CD84 antigen (leukocyte antigen) /FL=gb:AF054818.1 AF054818 CD84 molecule CD84 8832 NM_001184879 /// NM_001184881 /// NM_001184882 /// NM_003874 /// XR_241101 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211193_at AF061512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061512.1 /DEF=Homo sapiens p53 homolog (p40) mRNA, complete cds. /FEA=mRNA /GEN=p40 /PROD=p53 homolog /DB_XREF=gi:3273744 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AF061512.1 AF061512 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 211194_s_at AB010153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB010153.1 /DEF=Homo sapiens mRNA for p73H, complete cds. /FEA=mRNA /GEN=p73H /PROD=p73H /DB_XREF=gi:3445483 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AB010153.1 AB010153 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 211195_s_at AF116771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116771.1 /DEF=Homo sapiens p51 delta mRNA, complete cds. /FEA=mRNA /PROD=p51 delta /DB_XREF=gi:7384975 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AF116771.1 AF116771 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 211196_at M19301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M19301.1 /DEF=Human branched-chain alpha-keto acid dehydrogenase (E2) mRNA, complete cds. /FEA=mRNA /GEN=DBT /DB_XREF=gi:186635 /UG=Hs.139410 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) /FL=gb:M19301.1 M19301 dihydrolipoamide branched chain transacylase E2 DBT 1629 NM_001918 /// XM_005270545 /// XM_005270546 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0043754 // dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 211197_s_at AL355690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL355690.1 /DEF=Homo sapiens EST from clone 34465, full insert. /FEA=mRNA /DB_XREF=gi:7799138 /UG=Hs.14155 KIAA0653 protein, B7-like protein /FL=gb:AF216749.1 gb:AF289028.1 AL355690 inducible T-cell co-stimulator ligand ICOSLG 23308 NM_001283050 /// NM_001283051 /// NM_001283052 /// NM_015259 /// XM_005261098 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // non-traceable author statement /// 0006972 // hyperosmotic response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211198_s_at AF289028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF289028.1 /DEF=Homo sapiens transmembrane protein B7-H2 ICOS ligand mRNA, complete cds. /FEA=mRNA /PROD=transmembrane protein B7-H2 ICOS ligand /DB_XREF=gi:9858866 /UG=Hs.14155 KIAA0653 protein, B7-like protein /FL=gb:AF216749.1 gb:AF289028.1 AF289028 inducible T-cell co-stimulator ligand ICOSLG 23308 NM_001283050 /// NM_001283051 /// NM_001283052 /// NM_015259 /// XM_005261098 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // non-traceable author statement /// 0006972 // hyperosmotic response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211199_s_at AF199028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF199028.1 /DEF=Homo sapiens B7-like protein (GL50) mRNA, complete cds. /FEA=mRNA /GEN=GL50 /PROD=B7-like protein /DB_XREF=gi:6983943 /UG=Hs.14155 KIAA0653 protein, B7-like protein /FL=gb:AF199028.1 AF199028 inducible T-cell co-stimulator ligand ICOSLG 23308 NM_001283050 /// NM_001283051 /// NM_001283052 /// NM_015259 /// XM_005261098 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // non-traceable author statement /// 0006972 // hyperosmotic response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211200_s_at BC002836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002836.1 /DEF=Homo sapiens, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, clone MGC:3553, mRNA, complete cds. /FEA=mRNA /PROD=Gardner-Rasheed feline sarcoma viral (v-fgr)oncogene homolog /DB_XREF=gi:12803974 /UG=Hs.1422 Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog /FL=gb:BC002836.1 BC002836 EF-hand calcium binding domain 2 EFCAB2 84288 NM_001143943 /// NM_001290327 /// NM_032328 /// NR_026586 /// NR_026587 /// NR_026588 /// XM_006711830 /// XM_006711831 /// XM_006711832 /// XM_006711833 0005509 // calcium ion binding // inferred from electronic annotation 211201_at M95489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M95489.1 /DEF=H.sapiens follicle stimulating hormone receptor mRNA, complete cds. /FEA=mRNA /GEN=FSHR /PROD=follicle stimulating hormone receptor /DB_XREF=gi:182772 /UG=Hs.1428 follicle stimulating hormone receptor /FL=gb:M65085.1 gb:M95489.1 gb:NM_000145.1 M95489 follicle stimulating hormone receptor FSHR 2492 NM_000145 /// NM_181446 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001545 // primary ovarian follicle growth // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0003073 // regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008406 // gonad development // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0008585 // female gonad development // traceable author statement /// 0009992 // cellular water homeostasis // inferred from electronic annotation /// 0010640 // regulation of platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from electronic annotation /// 0033044 // regulation of chromosome organization // inferred from electronic annotation /// 0033146 // regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0035092 // sperm chromatin condensation // inferred from electronic annotation /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0045056 // transcytosis // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0060065 // uterus development // inferred from electronic annotation /// 0060408 // regulation of acetylcholine metabolic process // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004963 // follicle-stimulating hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation 211202_s_at AF087481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF087481.1 /DEF=Homo sapiens retinoblastoma binding protein 2 homolog 1 (RBBP2H1) mRNA, complete cds. /FEA=mRNA /GEN=RBBP2H1 /PROD=retinoblastoma binding protein 2 homolog 1 /DB_XREF=gi:4322487 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:AF087481.1 AF087481 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 211203_s_at U07820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U07820.1 /DEF=Human contactin 2 precursor (CNTN1) mRNA, complete cds. /FEA=mRNA /GEN=CNTN1 /PROD=h-contactin 2 precursor /DB_XREF=gi:469044 /UG=Hs.143434 contactin 1 /FL=gb:U07820.1 U07820 contactin 1 CNTN1 1272 NM_001256063 /// NM_001256064 /// NM_001843 /// NM_175038 /// XM_005268651 /// XM_006719241 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211204_at L34035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34035.1 /DEF=Homo sapiens NADP-dependent malic enzyme mRNA, complete cds. /FEA=mRNA /PROD=NADP-dependent malic enzyme /DB_XREF=gi:1322012 /UG=Hs.14732 malic enzyme 1, NADP(+)-dependent, cytosolic /FL=gb:L34035.1 L34035 malic enzyme 1, NADP(+)-dependent, cytosolic ME1 4199 NM_002395 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006108 // malate metabolic process // inferred from direct assay /// 0006741 // NADP biosynthetic process // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from sequence or structural similarity /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043531 // ADP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0051287 // NAD binding // traceable author statement 211205_x_at U78577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78577.1 /DEF=Human 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha mRNA, clone PIP5KIa3, complete cds. /FEA=mRNA /PROD=68 kDa type I phosphatidylinositol-4-phosphate5-kinase alpha /DB_XREF=gi:1743874 /UG=Hs.149255 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha /FL=gb:U78577.1 U78577 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha PIP5K1A 8394 NM_001135636 /// NM_001135637 /// NM_001135638 /// NM_003557 /// XM_005245525 /// XM_005245526 /// XM_005245527 /// XM_005245528 /// XM_005245529 /// XM_005245530 /// XM_005245531 /// XM_005245532 /// XM_006711563 /// XM_006711564 /// XM_006711565 /// XM_006711566 /// XM_006711567 /// XM_006711568 0006644 // phospholipid metabolic process // traceable author statement /// 0006650 // glycerophospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006909 // phagocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from direct assay /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement /// 0030216 // keratinocyte differentiation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype /// 0097178 // ruffle assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0016607 // nuclear speck // traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay 211207_s_at AF129166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF129166.1 /DEF=Homo sapiens long-chain acyl-CoA synthetase 5 (LACS5) mRNA, complete cds. /FEA=mRNA /GEN=LACS5 /PROD=long-chain acyl-CoA synthetase 5 /DB_XREF=gi:5702201 /UG=Hs.14945 long fatty acyl-CoA synthetase 2 gene /FL=gb:AF129166.1 AF129166 acyl-CoA synthetase long-chain family member 6 ACSL6 23305 NM_001009185 /// NM_001205247 /// NM_001205248 /// NM_001205250 /// NM_001205251 /// NM_015256 /// XM_006714579 /// XM_006714580 /// XM_006714581 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // non-traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010747 // positive regulation of plasma membrane long-chain fatty acid transport // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 211208_s_at AB039327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB039327.2 /DEF=Homo sapiens CASK mRNA for calciumcalmodulin-dependent serine protein kinase, complete cds. /FEA=mRNA /GEN=CASK /PROD=calciumcalmodulin-dependent serine proteinkinase /DB_XREF=gi:13359270 /UG=Hs.151469 calciumcalmodulin-dependent serine protein kinase (MAGUK family) /FL=gb:AB039327.2 AB039327 calcium/calmodulin-dependent serine protein kinase (MAGUK family) CASK 8573 NM_001126054 /// NM_001126055 /// NM_003688 /// XM_005272686 /// XM_006724565 /// XM_006724566 0001953 // negative regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0061045 // negative regulation of wound healing // inferred from mutant phenotype /// 0070509 // calcium ion import // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 0090288 // negative regulation of cellular response to growth factor stimulus // inferred from mutant phenotype 0005604 // basement membrane // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005652 // nuclear lamina // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004385 // guanylate kinase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from electronic annotation 211209_x_at AF100540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100540.1 /DEF=Homo sapiens SH2 domain protein 1A isoform C (SH2D1A) mRNA, complete cds. /FEA=mRNA /GEN=SH2D1A /PROD=SH2 domain protein 1A isoform C /DB_XREF=gi:3928895 /UG=Hs.151544 SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome) /FL=gb:AF100540.1 AF100540 SH2 domain containing 1A SH2D1A 4068 NM_001114937 /// NM_002351 0006959 // humoral immune response // inferred from electronic annotation /// 0006968 // cellular defense response // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211210_x_at AF100539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100539.1 /DEF=Homo sapiens SH2 domain protein 1A isoform B (SH2D1A) mRNA, complete cds. /FEA=mRNA /GEN=SH2D1A /PROD=SH2 domain protein 1A isoform B /DB_XREF=gi:3928893 /UG=Hs.151544 SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome) /FL=gb:AF100539.1 AF100539 SH2 domain containing 1A SH2D1A 4068 NM_001114937 /// NM_002351 0006959 // humoral immune response // inferred from electronic annotation /// 0006968 // cellular defense response // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211211_x_at AF100542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF100542.1 /DEF=Homo sapiens SH2 domain protein 1A isoform E (SH2D1A) mRNA, complete cds. /FEA=mRNA /GEN=SH2D1A /PROD=SH2 domain protein 1A isoform E /DB_XREF=gi:3928899 /UG=Hs.151544 SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome) /FL=gb:AF100542.1 AF100542 SH2 domain containing 1A SH2D1A 4068 NM_001114937 /// NM_002351 0006959 // humoral immune response // inferred from electronic annotation /// 0006968 // cellular defense response // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // non-traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211212_s_at AF081459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081459.1 /DEF=Homo sapiens origin recognition complex subunit ORC5T (ORC5L) mRNA, alternatively spliced product, complete cds. /FEA=mRNA /GEN=ORC5L /PROD=origin recognition complex subunit ORC5T /DB_XREF=gi:3766213 /UG=Hs.153138 origin recognition complex, subunit 5 (yeast homolog)-like /FL=gb:AF081459.1 AF081459 origin recognition complex, subunit 5 ORC5 5001 NM_001197292 /// NM_002553 /// NM_181747 /// XM_006716015 /// XR_242242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay /// 0005664 // nuclear origin of replication recognition complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003688 // DNA replication origin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 211213_at AF081459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081459.1 /DEF=Homo sapiens origin recognition complex subunit ORC5T (ORC5L) mRNA, alternatively spliced product, complete cds. /FEA=mRNA /GEN=ORC5L /PROD=origin recognition complex subunit ORC5T /DB_XREF=gi:3766213 /UG=Hs.153138 origin recognition complex, subunit 5 (yeast homolog)-like /FL=gb:AF081459.1 AF081459 origin recognition complex, subunit 5 ORC5 5001 NM_001197292 /// NM_002553 /// NM_181747 /// XM_006716015 /// XR_242242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay /// 0005664 // nuclear origin of replication recognition complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003688 // DNA replication origin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 211214_s_at BC003614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003614.1 /DEF=Homo sapiens, Similar to death-associated protein kinase 1, clone MGC:1468, mRNA, complete cds. /FEA=mRNA /PROD=Similar to death-associated protein kinase 1 /DB_XREF=gi:13177655 /UG=Hs.153924 death-associated protein kinase 1 /FL=gb:BC003614.1 BC003614 death-associated protein kinase 1 DAPK1 1612 NM_001288729 /// NM_001288730 /// NM_001288731 /// NM_004938 /// XM_005251757 /// XM_006716988 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211215_x_at AB041843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB041843.1 /DEF=Homo sapiens mRNA for type II iodothyronine deiodinase, complete cds. /FEA=mRNA /PROD=type II iodothyronine deiodinase /DB_XREF=gi:10863064 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:AB041843.1 AB041843 deiodinase, iodothyronine, type II DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 211217_s_at AF051426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF051426.1 /DEF=Homo sapiens slow delayed rectifier channel subunit mRNA, complete cds. /FEA=mRNA /PROD=slow delayed rectifier channel subunit /DB_XREF=gi:2961248 /UG=Hs.156115 potassium voltage-gated channel, KQT-like subfamily, member 1 /FL=gb:AF051426.1 AF051426 potassium voltage-gated channel, KQT-like subfamily, member 1 KCNQ1 3784 NM_000218 /// NM_181797 /// NM_181798 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008016 // regulation of heart contraction // inferred by curator /// 0008584 // male gonad development // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060306 // regulation of membrane repolarization // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060454 // positive regulation of gastric acid secretion // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086011 // membrane repolarization during action potential // inferred from direct assay /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // traceable author statement /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0008157 // protein phosphatase 1 binding // inferred from direct assay /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0086089 // voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization // inferred from mutant phenotype /// 0097110 // scaffold protein binding // inferred from physical interaction /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 211218_at AF118078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118078.1 /DEF=Homo sapiens PRO1848 mRNA, complete cds. /FEA=mRNA /PROD=PRO1848 /DB_XREF=gi:6650801 /UG=Hs.156243 PRO1848 protein /FL=gb:AF118078.1 AF118078 211219_s_at U11701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U11701.1 /DEF=Human LIM-homeobox domain protein (hLH-2) mRNA, complete cds. /FEA=mRNA /GEN=hLH-2 /PROD=LIM-homeobox domain protein /DB_XREF=gi:600494 /UG=Hs.1569 LIM homeobox protein 2 /FL=gb:U11701.1 U11701 LIM homeobox 2 LHX2 9355 NM_004789 /// XM_006717323 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021978 // telencephalon regionalization // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211220_s_at BC005329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005329.1 /DEF=Homo sapiens, Similar to heat shock transcription factor 2, clone MGC:12415, mRNA, complete cds. /FEA=mRNA /PROD=Similar to heat shock transcription factor 2 /DB_XREF=gi:13529106 /UG=Hs.158195 heat shock transcription factor 2 /FL=gb:BC005329.1 BC005329 heat shock transcription factor 2 HSF2 3298 NM_001135564 /// NM_001243094 /// NM_004506 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0001162 // RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211221_at AL117487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL117487.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L151 (from clone DKFZp434L151); complete cds. /FEA=mRNA /GEN=DKFZp434L151 /PROD=hypothetical protein /DB_XREF=gi:5911971 /UG=Hs.158196 transcriptional adaptor 3 (ADA3, yeast homolog)-like (PCAF histone acetylase complex) /FL=gb:AL117487.1 AL117487 transcriptional adaptor 3 TADA3 10474 NM_001278270 /// NM_006354 /// NM_133480 /// NM_133481 /// NR_103488 /// XM_006712930 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0090043 // regulation of tubulin deacetylation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation 211222_s_at AF040723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040723.1 /DEF=Homo sapiens neuroan1 mRNA, complete cds. /FEA=mRNA /PROD=neuroan1 /DB_XREF=gi:3282690 /UG=Hs.158300 huntingtin-associated protein 1 (neuroan 1) /FL=gb:AF040723.1 AF040723 huntingtin-associated protein 1 HAP1 9001 NM_001079870 /// NM_001079871 /// NM_003949 /// NM_177977 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // non-traceable author statement /// 0008104 // protein localization // inferred from mutant phenotype /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211223_at AF076215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF076215.1 /DEF=Homo sapiens prophet of Pit1 (PROP1) mRNA, complete cds. /FEA=mRNA /GEN=PROP1 /PROD=prophet of Pit1 /DB_XREF=gi:3873239 /UG=Hs.158301 prophet of Pit1, paired-like homeodomain transcription factor /FL=gb:AF076215.1 gb:NM_006261.1 AF076215 PROP paired-like homeobox 1 PROP1 5626 NM_006261 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021979 // hypothalamus cell differentiation // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0048850 // hypophysis morphogenesis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060126 // somatotropin secreting cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211224_s_at AF136523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF136523.1 /DEF=Homo sapiens bile salt export pump (BSEP) mRNA, complete cds. /FEA=mRNA /GEN=BSEP /PROD=bile salt export pump /DB_XREF=gi:4704819 /UG=Hs.158316 ATP-binding cassette, sub-family B (MDRTAP), member 11 /FL=gb:AF136523.1 AF136523 ATP-binding cassette, sub-family B (MDR/TAP), member 11 ABCB11 8647 NM_003742 /// XM_006712817 /// XM_006712818 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0015722 // canalicular bile acid transport // not recorded /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // not recorded 0000139 // Golgi membrane // /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // not recorded /// 0016324 // apical plasma membrane // /// 0045177 // apical part of cell // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008554 // sodium-exporting ATPase activity, phosphorylative mechanism // traceable author statement /// 0015126 // canalicular bile acid transmembrane transporter activity // not recorded /// 0015432 // bile acid-exporting ATPase activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded 211225_at U27329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27329.1 /DEF=Human alpha (1,3) fucosyltransferase (FUT5) mRNA, minor transcript I, complete cds. /FEA=mRNA /GEN=FUT5 /PROD=alpha (1,3) fucosyltransferase /DB_XREF=gi:967194 /UG=Hs.158327 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) /FL=gb:NM_002034.1 gb:U27329.1 gb:U27330.1 U27329 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) FUT5 2527 NM_002034 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 211226_at AF080586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF080586.1 /DEF=Homo sapiens galanin receptor type 2 (GALR2) mRNA, complete cds. /FEA=mRNA /GEN=GALR2 /PROD=galanin receptor type 2 /DB_XREF=gi:4165080 /UG=Hs.158351 galanin receptor 2 /FL=gb:AF040630.1 gb:AF080586.1 gb:NM_003857.2 AF080586 galanin receptor 2 GALR2 8811 NM_003857 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1902608 // positive regulation of large conductance calcium-activated potassium channel activity // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004966 // galanin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from direct assay 211227_s_at AF332216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332216.1 /DEF=Homo sapiens chromosome Y protocadherin 11 (PCDH11) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=PCDH11 /PROD=protocadherin 11 /DB_XREF=gi:13161056 /UG=Hs.159156 protocadherin 11 /FL=gb:AF332216.1 AF332216 protocadherin 11 X-linked /// protocadherin 11 Y-linked PCDH11X /// PCDH11Y 27328 /// 83259 NM_001168360 /// NM_001168361 /// NM_001168362 /// NM_001168363 /// NM_001278619 /// NM_014522 /// NM_032967 /// NM_032968 /// NM_032969 /// NM_032971 /// NM_032972 /// NM_032973 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 211228_s_at AF085736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF085736.1 /DEF=Homo sapiens RF-Cactivator 1 homolog (RAD17) mRNA, complete cds. /FEA=mRNA /GEN=RAD17 /PROD=RF-Cactivator 1 homolog /DB_XREF=gi:3641288 /UG=Hs.16184 RAD17 (S. pombe) homolog /FL=gb:AF085736.1 AF085736 RAD17 homolog (S. pombe) RAD17 5884 NM_001278622 /// NM_002873 /// NM_133338 /// NM_133339 /// NM_133340 /// NM_133341 /// NM_133342 /// NM_133343 /// NM_133344 /// XM_005276774 0000076 // DNA replication checkpoint // traceable author statement /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 211230_s_at U57843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U57843.1 /DEF=Human phosphatidylinositol 3-kinase delta catalytic subunit mRNA, complete cds. /FEA=mRNA /PROD=phosphatidylinositol 3-kinase delta catalyticsubunit /DB_XREF=gi:2076750 /UG=Hs.162808 phosphoinositide-3-kinase, catalytic, delta polypeptide /FL=gb:U57843.1 U57843 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta PIK3CD 5293 NM_005026 /// XM_005263473 /// XM_006710686 /// XM_006710687 /// XM_006710688 /// XM_006710689 /// XM_006710690 0001779 // natural killer cell differentiation // traceable author statement /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // traceable author statement /// 0002679 // respiratory burst involved in defense response // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010818 // T cell chemotaxis // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030101 // natural killer cell activation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0035747 // natural killer cell chemotaxis // traceable author statement /// 0035754 // B cell chemotaxis // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0043303 // mast cell degranulation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // traceable author statement /// 0060374 // mast cell differentiation // traceable author statement /// 0072672 // neutrophil extravasation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0042629 // mast cell granule // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 211231_x_at D13705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13705.1 /DEF=Human mRNA for fatty acids omega-hydroxylase (cytochrome P-450HKV), complete cds. /FEA=mRNA /PROD=fatty acid omega-hydroxylase /DB_XREF=gi:1197806 /UG=Hs.1645 cytochrome P450, subfamily IVA, polypeptide 11 /FL=gb:D13705.1 D13705 cytochrome P450, family 4, subfamily A, polypeptide 11 CYP4A11 1579 NM_000778 /// XM_005270537 /// XM_005270538 /// XM_005270539 /// XM_006710392 /// XR_246241 /// XR_246242 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0003091 // renal water homeostasis // inferred from expression pattern /// 0003095 // pressure natriuresis // inferred from expression pattern /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0032305 // positive regulation of icosanoid secretion // inferred from mutant phenotype /// 0036101 // leukotriene B4 catabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from direct assay /// 0052869 // arachidonic acid omega-hydroxylase activity // inferred from electronic annotation 211232_x_at L23503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23503.1 /DEF=Human glucagon-like peptide-1 receptor (GLP-1) mRNA, complete cds. /FEA=mRNA /GEN=GLP-1 /PROD=glucagon-like peptide-1 receptor /DB_XREF=gi:402480 /UG=Hs.165 glucagon-like peptide 1 receptor /FL=gb:U01156.1 gb:L23503.1 L23503 glucagon-like peptide 1 receptor GLP1R 2740 NM_002062 /// XM_006715065 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004967 // glucagon receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 211233_x_at M12674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M12674.1 /DEF=Human estrogen receptor mRNA, complete cds. /FEA=mRNA /GEN=ESR /DB_XREF=gi:182192 /UG=Hs.1657 estrogen receptor 1 /FL=gb:M12674.1 M12674 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211234_x_at AF258449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF258449.1 /DEF=Homo sapiens estrogen receptor alpha mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=estrogen receptor alpha /DB_XREF=gi:11907834 /UG=Hs.1657 estrogen receptor 1 /FL=gb:AF258449.1 AF258449 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211235_s_at AF258450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF258450.1 /DEF=Homo sapiens estrogen receptor alpha mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=estrogen receptor alpha /DB_XREF=gi:11907836 /UG=Hs.1657 estrogen receptor 1 /FL=gb:AF258450.1 AF258450 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211237_s_at AF202063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF202063.1 /DEF=Homo sapiens fibroblast growth factor receptor 4, soluble-form splice variant (FGFR4) mRNA, complete cds. /FEA=mRNA /GEN=FGFR4 /PROD=fibroblast growth factor receptor 4,soluble-form splice variant /DB_XREF=gi:6739817 /UG=Hs.165950 fibroblast growth factor receptor 4 /FL=gb:NM_022963.1 gb:AF202063.1 AF202063 fibroblast growth factor receptor 4 FGFR4 2264 NM_001291980 /// NM_002011 /// NM_022963 /// NM_213647 /// XM_005265837 /// XM_005265838 /// XR_427801 0001759 // organ induction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048554 // positive regulation of metalloenzyme activity // inferred from mutant phenotype /// 0055062 // phosphate ion homeostasis // inferred from sequence or structural similarity /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070857 // regulation of bile acid biosynthetic process // inferred from mutant phenotype /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 211238_at AF215824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF215824.1 /DEF=Homo sapiens a disintegrin and metalloproteinase 7 (ADAM7) mRNA, complete cds. /FEA=mRNA /GEN=ADAM7 /PROD=a disintegrin and metalloproteinase 7 /DB_XREF=gi:12004291 /UG=Hs.166003 a disintegrin and metalloproteinase domain 7 /FL=gb:AF215824.1 AF215824 ADAM metallopeptidase domain 7 ADAM7 8756 NM_003817 /// XM_005273668 /// XM_005273669 /// XM_005273670 /// XM_005273671 /// XM_005273672 /// XM_005273673 0006508 // proteolysis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 211239_s_at AF215824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF215824.1 /DEF=Homo sapiens a disintegrin and metalloproteinase 7 (ADAM7) mRNA, complete cds. /FEA=mRNA /GEN=ADAM7 /PROD=a disintegrin and metalloproteinase 7 /DB_XREF=gi:12004291 /UG=Hs.166003 a disintegrin and metalloproteinase domain 7 /FL=gb:AF215824.1 AF215824 ADAM metallopeptidase domain 7 ADAM7 8756 NM_003817 /// XM_005273668 /// XM_005273669 /// XM_005273670 /// XM_005273671 /// XM_005273672 /// XM_005273673 0006508 // proteolysis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 211240_x_at AB002382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB002382.1 /DEF=Human mRNA for KIAA0384 gene, complete cds. /FEA=mRNA /GEN=KIAA0384 /DB_XREF=gi:2224708 /UG=Hs.166011 catenin (cadherin-associated protein), delta 1 /FL=gb:AB002382.1 AB002382 catenin (cadherin-associated protein), delta 1 /// TMX2-CTNND1 readthrough (NMD candidate) CTNND1 /// TMX2-CTNND1 1500 /// 100528016 NM_001085458 /// NM_001085459 /// NM_001085460 /// NM_001085461 /// NM_001085462 /// NM_001085463 /// NM_001085464 /// NM_001085465 /// NM_001085466 /// NM_001085467 /// NM_001085468 /// NM_001085469 /// NM_001206883 /// NM_001206884 /// NM_001206885 /// NM_001206886 /// NM_001206887 /// NM_001206888 /// NM_001206889 /// NM_001206890 /// NM_001206891 /// NM_001331 /// NR_037646 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0060690 // epithelial cell differentiation involved in salivary gland development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 211241_at M62895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M62895.1 /DEF=Human lipocortin (LIP) 2 pseudogene mRNA, complete cds-like region. /FEA=mRNA /DB_XREF=gi:187145 /UG=Hs.166072 annexin A2 pseudogene 2 /FL=gb:M62895.1 M62895 annexin A2 pseudogene 3 ANXA2P3 305 NR_001446 0001525 // angiogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 211242_x_at AF276292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF276292.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor KIR2DL4 mRNA, complete cds. /FEA=mRNA /PROD=killer cell immunoglobulin-like receptorKIR2DL4 /DB_XREF=gi:12006296 /UG=Hs.166085 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 /FL=gb:AF285436.1 gb:AF276292.1 gb:U71199.1 gb:AF002979.1 gb:AF034771.1 gb:AF034772.1 gb:AF034773.1 AF276292 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 KIR2DL4 3805 NM_001080770 /// NM_001080772 /// NM_001258383 /// NM_002255 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211245_x_at AF002256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF002256.1 /DEF=Homo sapiens killer cell inhibitory receptor homolog cl-9 mRNA, complete cds. /FEA=mRNA /PROD=cl-9 /DB_XREF=gi:2197058 /UG=Hs.166085 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 /FL=gb:AF002256.1 AF002256 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 KIR2DL4 3805 NM_001080770 /// NM_001080772 /// NM_001258383 /// NM_002255 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211248_s_at AF283325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF283325.1 /DEF=Homo sapiens chordin variant 3 (CHRD) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=CHRD /PROD=chordin variant 3 /DB_XREF=gi:11494372 /UG=Hs.166186 chordin /FL=gb:AF283325.1 AF283325 chordin CHRD 8646 NM_003741 /// NM_177978 /// NM_177979 /// XM_005247848 /// XM_005247849 /// XM_005247850 /// XM_005247851 /// XR_427383 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021919 // BMP signaling pathway involved in spinal cord dorsal/ventral patterning // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0033504 // floor plate development // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0019955 // cytokine binding // non-traceable author statement /// 0045545 // syndecan binding // inferred from electronic annotation 211249_at U35398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35398.1 /DEF=Human G protein-coupled receptor mRNA, complete cds. /FEA=mRNA /PROD=G protein-coupled receptor /DB_XREF=gi:1015418 /UG=Hs.166607 G protein-coupled receptor 68 /FL=gb:U35398.1 gb:NM_003485.1 U35398 G protein-coupled receptor 68 GPR68 8111 NM_001177676 /// NM_003485 /// XM_005268110 /// XM_005268111 /// XM_005268112 /// XM_006720262 /// XM_006720263 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 211250_s_at AB000463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB000463.1 /DEF=Homo sapiens mRNA, complete cds, clone:RES4-23B. /FEA=mRNA /DB_XREF=gi:1843393 /UG=Hs.167679 SH3-domain binding protein 2 /FL=gb:AB000463.1 AB000463 SH3-domain binding protein 2 SH3BP2 6452 NM_001122681 /// NM_001145855 /// NM_001145856 /// NM_003023 /// XM_005247997 /// XM_005247998 /// XM_005247999 /// XM_005248000 /// XM_006713911 /// XM_006713912 /// XM_006713913 0007165 // signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 211251_x_at U78774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U78774.1 /DEF=Human NFY-C mRNA, complete cds. /FEA=mRNA /PROD=NFY-C /DB_XREF=gi:2327008 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:U78774.1 U78774 nuclear transcription factor Y, gamma NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211252_x_at U36759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U36759.1 /DEF=Human pre-T cell receptor alpha-type chain precursor, mRNA, complete cds. /FEA=mRNA /PROD=pre-T cell receptor alpha-type chain precursor /DB_XREF=gi:1127580 /UG=Hs.169002 Human pre TCR alpha mRNA, partial cds /FL=gb:U36759.1 U36759 pre T-cell antigen receptor alpha PTCRA 171558 NM_001243168 /// NM_001243169 /// NM_001243170 /// NM_138296 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211253_x_at D13902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13902.1 /DEF=Human mRNA for peptide YY, complete cds. /FEA=mRNA /PROD=peptide YY precursor /DB_XREF=gi:391728 /UG=Hs.169249 peptide YY /FL=gb:D13902.1 D13902 peptide YY PYY 5697 NM_004160 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007586 // digestion // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0042755 // eating behavior // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211254_x_at AF031549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031549.1 /DEF=Homo sapiens mutant erythrocyte membrane glycoprotein Rh50 (Rh50) mRNA, complete cds. /FEA=mRNA /GEN=Rh50 /PROD=mutant erythrocyte membrane glycoprotein Rh50 /DB_XREF=gi:2909820 /UG=Hs.169536 Rhesus blood group-associated glycoprotein /FL=gb:AF031549.1 AF031549 Rh-associated glycoprotein RHAG 6005 NM_000324 0006810 // transport // inferred from electronic annotation /// 0006873 // cellular ion homeostasis // inferred from direct assay /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from genetic interaction /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from genetic interaction 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0008519 // ammonium transmembrane transporter activity // inferred from genetic interaction /// 0030506 // ankyrin binding // inferred from physical interaction 211255_x_at AF064605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064605.1 /DEF=Homo sapiens KE05 protein mRNA, complete cds. /FEA=mRNA /PROD=KE05 protein /DB_XREF=gi:3152663 /UG=Hs.169681 death effector domain-containing /FL=gb:AF064605.1 AF064605 death effector domain containing DEDD 9191 NM_001039711 /// NM_001039712 /// NM_004216 /// NM_032998 /// XM_005245597 /// XM_005245598 /// XM_005245599 /// XM_005245600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 211256_x_at U90142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90142.1 /DEF=Human unknown protein (BT2.1) mRNA, complete cds. /FEA=mRNA /GEN=BT2.1 /PROD=unknown protein /DB_XREF=gi:1899191 /UG=Hs.169963 butyrophilin, subfamily 2, member A1 /FL=gb:U90142.1 U90142 butyrophilin, subfamily 2, member A1 BTN2A1 11120 NM_001197233 /// NM_001197234 /// NM_007049 /// NM_078476 0006629 // lipid metabolic process // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 211257_x_at AF273049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF273049.1 /DEF=Homo sapiens CTCL tumor antigen se33-1 mRNA, complete cds. /FEA=mRNA /PROD=CTCL tumor antigen se33-1 /DB_XREF=gi:11385655 /UG=Hs.169984 nuclear protein /FL=gb:AF273049.1 AF273049 zinc finger protein 638 ZNF638 27332 NM_001014972 /// NM_001252612 /// NM_001252613 /// NM_014497 /// XM_005264261 /// XM_005264262 /// XM_005264263 /// XM_005264264 /// XM_006711989 /// XM_006711990 /// XR_244928 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211258_s_at AF149096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF149096.1 /DEF=Homo sapiens transforming growth factor-alpha variant I mRNA, alternatively spliced product, complete cds. /FEA=mRNA /PROD=transforming growth factor-alpha variant I /DB_XREF=gi:6175597 /UG=Hs.170009 transforming growth factor, alpha /FL=gb:AF149096.1 gb:AF149097.1 AF149096 transforming growth factor, alpha TGFA 7039 NM_001099691 /// NM_003236 /// XM_005264522 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0048523 // negative regulation of cellular process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 211259_s_at BC004248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004248.1 /DEF=Homo sapiens, Similar to bone morphogenetic protein 7 (osteogenic protein 1), clone MGC:10550, mRNA, complete cds. /FEA=mRNA /PROD=Similar to bone morphogenetic protein 7(osteogenic protein 1) /DB_XREF=gi:13279013 /UG=Hs.170195 bone morphogenetic protein 7 (osteogenic protein 1) /FL=gb:BC004248.1 BC004248 bone morphogenetic protein 7 BMP7 655 NM_001719 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from expression pattern /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0016358 // dendrite development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity /// 0072040 // negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis // inferred from electronic annotation /// 0072125 // negative regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1900106 // positive regulation of hyaluranon cable assembly // inferred from direct assay /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 211260_at BC004248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004248.1 /DEF=Homo sapiens, Similar to bone morphogenetic protein 7 (osteogenic protein 1), clone MGC:10550, mRNA, complete cds. /FEA=mRNA /PROD=Similar to bone morphogenetic protein 7(osteogenic protein 1) /DB_XREF=gi:13279013 /UG=Hs.170195 bone morphogenetic protein 7 (osteogenic protein 1) /FL=gb:BC004248.1 BC004248 bone morphogenetic protein 7 BMP7 655 NM_001719 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001823 // mesonephros development // inferred from expression pattern /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0016358 // dendrite development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity /// 0072040 // negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis // inferred from electronic annotation /// 0072125 // negative regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from direct assay /// 1900106 // positive regulation of hyaluranon cable assembly // inferred from direct assay /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 211261_at D14689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D14689.1 /DEF=Human mRNA for KIAA0023 gene, complete cds. /FEA=mRNA /GEN=KIAA0023 /DB_XREF=gi:285956 /UG=Hs.170285 nucleoporin 214kD (CAIN) /FL=gb:D14689.1 D14689 nucleoporin 214kDa NUP214 8021 NM_005085 /// XM_005272216 /// XM_005272217 /// XM_005272218 /// XM_005272219 /// XM_006717292 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211262_at D28513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D28513.1 /DEF=Human mRNA for PACE4C (kexin-like protease), complete cds. /FEA=mRNA /PROD=PACE4C /DB_XREF=gi:666010 /UG=Hs.170414 paired basic amino acid cleaving system 4 /FL=gb:D28513.1 D28513 proprotein convertase subtilisin/kexin type 6 PCSK6 5046 NM_001291309 /// NM_002570 /// NM_138319 /// NM_138320 /// NM_138321 /// NM_138322 /// NM_138323 /// NM_138324 /// NM_138325 0006508 // proteolysis // inferred from electronic annotation /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032940 // secretion by cell // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 211263_s_at D87994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87994.1 /DEF=Homo sapiens mRNA for PACE4E-II, complete cds. /FEA=mRNA /PROD=PACE4E-II /DB_XREF=gi:2330550 /UG=Hs.170414 paired basic amino acid cleaving system 4 /FL=gb:D87994.1 D87994 proprotein convertase subtilisin/kexin type 6 PCSK6 5046 NM_001291309 /// NM_002570 /// NM_138319 /// NM_138320 /// NM_138321 /// NM_138322 /// NM_138323 /// NM_138324 /// NM_138325 0006508 // proteolysis // inferred from electronic annotation /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0030510 // regulation of BMP signaling pathway // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032940 // secretion by cell // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 211264_at M81882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81882.1 /DEF=Human glutamate decarboxylase (GAD65) mRNA, complete cds. /FEA=mRNA /GEN=GAD65 /PROD=glutamate decarboxylase /DB_XREF=gi:182933 /UG=Hs.170808 glutamate decarboxylase 2 (pancreatic islets and brain, 65kD) /FL=gb:M81882.1 M81882 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) GAD2 2572 NM_000818 /// NM_001134366 0006540 // glutamate decarboxylation to succinate // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211265_at U13216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13216.1 /DEF=Human protaglandin receptor EP3A1 mRNA, complete cds. /FEA=mRNA /PROD=protaglandin receptor EP3A1 /DB_XREF=gi:532741 /UG=Hs.170917 prostaglandin E receptor 3 (subtype EP3) /FL=gb:U13216.1 U13216 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 211266_s_at U35399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35399.1 /DEF=Human G protein-coupled receptor mRNA, complete cds. /FEA=mRNA /PROD=G protein-coupled receptor /DB_XREF=gi:1015420 /UG=Hs.17170 G protein-coupled receptor 4 /FL=gb:U35399.1 U35399 G protein-coupled receptor 4 GPR4 2828 NM_005282 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 211267_at U82811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U82811.1 /DEF=Human homeodomain-containing protein (HANF) mRNA, complete cds. /FEA=mRNA /GEN=HANF /PROD=HANF /DB_XREF=gi:2662410 /UG=Hs.171980 homeo box (expressed in ES cells) 1 /FL=gb:U82811.1 gb:NM_003865.1 U82811 HESX homeobox 1 HESX1 8820 NM_003865 /// XM_005265526 /// XM_006713379 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0030916 // otic vesicle formation // inferred from electronic annotation /// 0043584 // nose development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 211269_s_at K03122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03122.1 /DEF=Human interleukin-2 receptor mRNA (short form), complete cds. /FEA=mRNA /GEN=IL2R /DB_XREF=gi:186319 /UG=Hs.1724 interleukin 2 receptor, alpha /FL=gb:K03122.1 K03122 interleukin 2 receptor, alpha IL2RA 3559 NM_000417 /// XM_005252446 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0038110 // interleukin-2-mediated signaling pathway // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0046013 // regulation of T cell homeostatic proliferation // inferred from electronic annotation /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004911 // interleukin-2 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0019976 // interleukin-2 binding // inferred from electronic annotation 211270_x_at BC002397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002397.1 /DEF=Homo sapiens, polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I), clone MGC:8461, mRNA, complete cds. /FEA=mRNA /PROD=polypyrimidine tract binding protein(heterogeneous nuclear ribonucleoprotein I) /DB_XREF=gi:12803182 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) /FL=gb:BC002397.1 BC002397 polypyrimidine tract binding protein 1 PTBP1 5725 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 211271_x_at BC004383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004383.1 /DEF=Homo sapiens, Similar to polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I), clone MGC:10830, mRNA, complete cds. /FEA=mRNA /PROD=Similar to polypyrimidine tract binding protein(heterogeneous nuclear ribonucleoprotein I) /DB_XREF=gi:13325139 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) /FL=gb:BC004383.1 BC004383 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 211272_s_at AF064771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064771.1 /DEF=Homo sapiens clone 24 diacylglycerol kinase alpha (DAGK1) mRNA, complete cds. /FEA=mRNA /GEN=DAGK1 /PROD=diacylglycerol kinase alpha /DB_XREF=gi:3551833 /UG=Hs.172690 diacylglycerol kinase, alpha (80kD) /FL=gb:AF064771.1 AF064771 diacylglycerol kinase, alpha 80kDa DGKA 1606 NM_001345 /// NM_201444 /// NM_201445 /// NM_201554 /// XM_005268688 /// XM_005268689 /// XM_005268690 /// XM_006719260 /// XR_429084 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211273_s_at AF012130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF012130.1 /DEF=Homo sapiens brachyury variant A (TBX1) mRNA, complete cds. /FEA=mRNA /GEN=TBX1 /PROD=brachyury /DB_XREF=gi:2735860 /UG=Hs.173984 T-box 1 /FL=gb:AF012130.1 AF012130 T-box 1 TBX1 6899 NM_005992 /// NM_080646 /// NM_080647 /// XM_005261269 /// XM_006724312 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0021644 // vagus nerve morphogenesis // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042471 // ear morphogenesis // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042473 // outer ear morphogenesis // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043587 // tongue morphogenesis // inferred from sequence or structural similarity /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from mutant phenotype /// 0048644 // muscle organ morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from mutant phenotype /// 0048752 // semicircular canal morphogenesis // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0060017 // parathyroid gland development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from sequence or structural similarity /// 0060415 // muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0070166 // enamel mineralization // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071600 // otic vesicle morphogenesis // inferred from electronic annotation /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0097152 // mesenchymal cell apoptotic process // inferred from sequence or structural similarity /// 2000027 // regulation of organ morphogenesis // inferred from sequence or structural similarity /// 2001037 // positive regulation of tongue muscle cell differentiation // inferred from sequence or structural similarity /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // traceable author statement 211274_at AF012130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF012130.1 /DEF=Homo sapiens brachyury variant A (TBX1) mRNA, complete cds. /FEA=mRNA /GEN=TBX1 /PROD=brachyury /DB_XREF=gi:2735860 /UG=Hs.173984 T-box 1 /FL=gb:AF012130.1 AF012130 T-box 1 TBX1 6899 NM_005992 /// NM_080646 /// NM_080647 /// XM_005261269 /// XM_006724312 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001945 // lymph vessel development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from sequence or structural similarity /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0021644 // vagus nerve morphogenesis // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042471 // ear morphogenesis // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042473 // outer ear morphogenesis // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042693 // muscle cell fate commitment // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043587 // tongue morphogenesis // inferred from sequence or structural similarity /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from mutant phenotype /// 0048644 // muscle organ morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048703 // embryonic viscerocranium morphogenesis // inferred from mutant phenotype /// 0048752 // semicircular canal morphogenesis // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0060017 // parathyroid gland development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from sequence or structural similarity /// 0060415 // muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0070166 // enamel mineralization // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071600 // otic vesicle morphogenesis // inferred from electronic annotation /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0097152 // mesenchymal cell apoptotic process // inferred from sequence or structural similarity /// 2000027 // regulation of organ morphogenesis // inferred from sequence or structural similarity /// 2001037 // positive regulation of tongue muscle cell differentiation // inferred from sequence or structural similarity /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // traceable author statement 211275_s_at AF087942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF087942.1 /DEF=Homo sapiens glycogenin-1L mRNA, complete cds. /FEA=mRNA /PROD=glycogenin-1L /DB_XREF=gi:5814084 /UG=Hs.174071 glycogenin /FL=gb:AF087942.1 AF087942 glycogenin 1 GYG1 2992 NM_001184720 /// NM_001184721 /// NM_004130 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211276_at AF063606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF063606.1 /DEF=Homo sapiens brain my048 protein mRNA, complete cds. /FEA=mRNA /PROD=brain my048 protein /DB_XREF=gi:12002041 /UG=Hs.17481 Homo sapiens clone 24606 mRNA sequence /FL=gb:AF063606.1 AF063606 transcription elongation factor A (SII)-like 2 TCEAL2 140597 NM_080390 /// XM_006724621 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 211277_x_at BC004369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004369.1 /DEF=Homo sapiens, Similar to amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease), clone MGC:10403, mRNA, complete cds. /FEA=mRNA /PROD=Similar to amyloid beta (A4) precursor protein(protease nexin-II, Alzheimer disease) /DB_XREF=gi:13325111 /UG=Hs.177486 amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) /FL=gb:BC004369.1 BC004369 amyloid beta (A4) precursor protein APP 351 NM_000484 /// NM_001136016 /// NM_001136129 /// NM_001136130 /// NM_001136131 /// NM_001204301 /// NM_001204302 /// NM_001204303 /// NM_201413 /// NM_201414 0000085 // mitotic G2 phase // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007617 // mating behavior // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008088 // axon cargo transport // inferred from sequence or structural similarity /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048669 // collateral sprouting in absence of injury // inferred from sequence or structural similarity /// 0050803 // regulation of synapse structure and activity // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051124 // synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from direct assay /// 0043198 // dendritic shaft // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from electronic annotation 211279_at L22454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L22454.1 /DEF=Homo sapiens nuclear respiratory factor-1 (NRF-1) mRNA, complete cds. /FEA=mRNA /PROD=nuclear respiratory factor-1 /DB_XREF=gi:347959 /UG=Hs.180069 nuclear respiratory factor 1 /FL=gb:L22454.1 L22454 nuclear respiratory factor 1 NRF1 4899 NM_001040110 /// NM_001293163 /// NM_001293164 /// NM_005011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation 211280_s_at L22454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L22454.1 /DEF=Homo sapiens nuclear respiratory factor-1 (NRF-1) mRNA, complete cds. /FEA=mRNA /PROD=nuclear respiratory factor-1 /DB_XREF=gi:347959 /UG=Hs.180069 nuclear respiratory factor 1 /FL=gb:L22454.1 L22454 nuclear respiratory factor 1 NRF1 4899 NM_001040110 /// NM_001293163 /// NM_001293164 /// NM_005011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation 211282_x_at U94506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94506.1 /DEF=Human lymphocyte associated receptor of death 5 mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=lymphocyte associated receptor of death 5 /DB_XREF=gi:2071958 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) /FL=gb:U94506.1 U94506 tumor necrosis factor receptor superfamily, member 25 TNFRSF25 8718 NM_001039664 /// NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148974 0006915 // apoptotic process // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211284_s_at BC000324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000324.1 /DEF=Homo sapiens, Similar to granulin, clone MGC:8480, mRNA, complete cds. /FEA=mRNA /PROD=Similar to granulin /DB_XREF=gi:12653114 /UG=Hs.180577 granulin /FL=gb:BC000324.1 BC000324 granulin GRN 2896 NM_001012479 /// NM_002087 /// XM_005257253 0001835 // blastocyst hatching // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211285_s_at U84404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U84404.1 /DEF=Human E6-associated protein E6-APubiquitin-protein ligase (UBE3A) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=UBE3A /PROD=E6-associated protein E6-APubiquitin-proteinligase /DB_XREF=gi:1872513 /UG=Hs.180686 ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) /FL=gb:AF273050.1 gb:U84404.1 U84404 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0035037 // sperm entry // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 211286_x_at L29349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L29349.1 /DEF=Homo sapiens granulocyte-macrophage colony-stimulating factor receptor alpha-subunit 3 (GM-CSF-RA3) mRNA, complete cds. /FEA=mRNA /GEN=GM-CSF-RA3 /PROD=granulocyte-macrophage colony-stimulating factorreceptor alpha-subunit 3 /DB_XREF=gi:460284 /UG=Hs.182378 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) /FL=gb:L29349.1 L29349 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CSF2RA 1438 NM_001161529 /// NM_001161530 /// NM_001161531 /// NM_001161532 /// NM_006140 /// NM_172245 /// NM_172246 /// NM_172247 /// NM_172248 /// NM_172249 /// NR_027760 /// XM_006724437 /// XM_006724438 /// XM_006724439 /// XM_006724440 /// XM_006724441 /// XM_006724858 /// XM_006724859 /// XM_006724860 /// XM_006724861 /// XM_006724862 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211287_x_at M64445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M64445.1 /DEF=Human GM-CSF receptor mRNA, complete cds. /FEA=mRNA /GEN=GM-CSF receptor /PROD=GM-CSF receptor /DB_XREF=gi:183361 /UG=Hs.182378 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) /FL=gb:M64445.1 M64445 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CSF2RA 1438 NM_001161529 /// NM_001161530 /// NM_001161531 /// NM_001161532 /// NM_006140 /// NM_172245 /// NM_172246 /// NM_172247 /// NM_172248 /// NM_172249 /// NR_027760 /// XM_006724437 /// XM_006724438 /// XM_006724439 /// XM_006724440 /// XM_006724441 /// XM_006724858 /// XM_006724859 /// XM_006724860 /// XM_006724861 /// XM_006724862 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211289_x_at AF067524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067524.1 /DEF=Homo sapiens PITSLRE protein kinase beta SV12 isoform (CDC2L2) mRNA, complete cds. /FEA=mRNA /GEN=CDC2L2 /PROD=PITSLRE protein kinase beta SV12 isoform /DB_XREF=gi:3850327 /UG=Hs.183418 cell division cycle 2-like 1 (PITSLRE proteins) /FL=gb:AF067524.1 AF067524 cyclin-dependent kinase 11A /// cyclin-dependent kinase 11B CDK11A /// CDK11B 984 /// 728642 NM_001291345 /// NM_001787 /// NM_024011 /// NM_033486 /// NM_033487 /// NM_033488 /// NM_033489 /// NM_033490 /// NM_033492 /// NM_033493 /// NM_033527 /// NM_033529 /// NM_033532 /// NM_033534 /// XM_006711061 /// XM_006711062 /// XM_006711063 /// XM_006711064 /// XM_006711065 /// XM_006711066 /// XM_006711067 /// XM_006711068 /// XM_006711069 /// XM_006711070 /// XM_006711071 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211295_x_at AF182275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF182275.1 /DEF=Homo sapiens cytochrome P450-2A6 (CYP2A6) mRNA, complete cds. /FEA=mRNA /GEN=CYP2A6 /PROD=cytochrome P450-2A6 /DB_XREF=gi:6470138 /UG=Hs.183584 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 /FL=gb:AF182275.1 AF182275 cytochrome P450, family 2, subfamily A, polypeptide 6 CYP2A6 1548 NM_000762 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211296_x_at AB009010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009010.1 /DEF=Homo sapiens mRNA for polyubiquitin UbC, complete cds. /FEA=mRNA /GEN=UbC1 /PROD=polyubiquitin UbC /DB_XREF=gi:2647407 /UG=Hs.183704 ubiquitin C /FL=gb:BC000449.1 gb:AB009010.1 AB009010 ubiquitin C UBC 7316 NM_021009 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211297_s_at L20320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20320.1 /DEF=Human protein serinethreonine kinase stk1 mRNA, complete cds. /FEA=mRNA /PROD=protein serinethreonine kinase /DB_XREF=gi:348242 /UG=Hs.184298 cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) /FL=gb:L20320.1 L20320 cyclin-dependent kinase 7 CDK7 1022 NM_001799 /// XM_005248398 /// XM_005276756 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 211298_s_at AF116645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116645.1 /DEF=Homo sapiens PRO1708 mRNA, complete cds. /FEA=mRNA /PROD=PRO1708 /DB_XREF=gi:7959790 /UG=Hs.184411 albumin /FL=gb:AF116645.1 AF116645 albumin ALB 213 NM_000477 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008206 // bile acid metabolic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0019836 // hemolysis by symbiont of host erythrocytes // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // non-traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0051659 // maintenance of mitochondrion location // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070541 // response to platinum ion // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005504 // fatty acid binding // non-traceable author statement /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015643 // toxic substance binding // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0019825 // oxygen binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 211299_s_at BC003683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003683.1 /DEF=Homo sapiens, Similar to flotillin 2, clone MGC:5052, mRNA, complete cds. /FEA=mRNA /PROD=Similar to flotillin 2 /DB_XREF=gi:13277549 /UG=Hs.184488 flotillin 2 /FL=gb:BC003683.1 BC003683 flotillin 2 FLOT2 2319 NM_004475 /// XM_005257950 /// XM_005257952 /// XM_005257953 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 1902992 // negative regulation of amyloid precursor protein catabolic process // inferred from mutant phenotype 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 211300_s_at K03199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03199.1 /DEF=Human p53 cellular tumor antigen mRNA, complete cds. /FEA=mRNA /GEN=TP53 /DB_XREF=gi:189478 /UG=Hs.1846 tumor protein p53 (Li-Fraumeni syndrome) /FL=gb:K03199.1 K03199 tumor protein p53 TP53 7157 NM_000546 /// NM_001126112 /// NM_001126113 /// NM_001126114 /// NM_001126115 /// NM_001126116 /// NM_001126117 /// NM_001126118 /// NM_001276695 /// NM_001276696 /// NM_001276697 /// NM_001276698 /// NM_001276699 /// NM_001276760 /// NM_001276761 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0007369 // gastrulation // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from direct assay /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0009303 // rRNA transcription // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010332 // response to gamma radiation // inferred from mutant phenotype /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // not recorded /// 0031497 // chromatin assembly // inferred from direct assay /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034103 // regulation of tissue remodeling // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0034644 // cellular response to UV // not recorded /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046902 // regulation of mitochondrial membrane permeability // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051097 // negative regulation of helicase activity // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090343 // positive regulation of cell aging // inferred from electronic annotation /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097252 // oligodendrocyte apoptotic process // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901525 // negative regulation of macromitophagy // inferred from electronic annotation /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // not recorded /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from physical interaction /// 0097371 // MDM2/MDM4 family protein binding // inferred from electronic annotation 211301_at AF120491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF120491.1 /DEF=Homo sapiens Sha1-related potassium channel Kv4.3 (KCND3) mRNA, long splice variant, complete cds. /FEA=mRNA /GEN=KCND3 /PROD=Sha1-related potassium channel Kv4.3 /DB_XREF=gi:5059059 /UG=Hs.184889 potassium voltage-gated channel, Shal-related subfamily, member 3 /FL=gb:AF048713.1 gb:NM_004980.1 gb:AF120491.1 gb:AF187963.1 gb:AF205857.1 AF120491 potassium voltage-gated channel, Shal-related subfamily, member 3 KCND3 3752 NM_004980 /// NM_172198 /// XM_005270851 /// XM_006710629 /// XM_006710630 /// XM_006710631 /// XM_006710632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0086009 // membrane repolarization // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005250 // A-type (transient outward) potassium channel activity // not recorded /// 0005250 // A-type (transient outward) potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211302_s_at L20966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20966.1 /DEF=Human phosphodiesterase mRNA, complete cds. /FEA=mRNA /PROD=phosphodiesterase /DB_XREF=gi:347121 /UG=Hs.188 phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4) /FL=gb:L20966.1 L20966 phosphodiesterase 4B, cAMP-specific PDE4B 5142 NM_001037339 /// NM_001037340 /// NM_001037341 /// NM_001297440 /// NM_001297441 /// NM_001297442 /// NM_002600 /// XM_005270923 /// XM_005270924 /// XM_005270925 /// XM_005270926 /// XM_006710680 0001780 // neutrophil homeostasis // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211303_x_at AF261715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF261715.1 /DEF=Homo sapiens prostate-specific membrane antigen-like protein (PSMALGCP III) mRNA, complete cds. /FEA=mRNA /GEN=PSMALGCP III /PROD=prostate-specific membrane antigen-like protein /DB_XREF=gi:11078563 /UG=Hs.1915 folate hydrolase (prostate-specific membrane antigen) 1 /FL=gb:AF261715.1 AF261715 folate hydrolase 1B FOLH1B 219595 NM_153696 /// XM_006718776 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211304_x_at D50134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50134.1 /DEF=Homo sapiens mRNA for inward rectifying K channel, complete cds. /FEA=mRNA /PROD=inward rectifying K channel /DB_XREF=gi:1890045 /UG=Hs.193044 potassium inwardly-rectifying channel, subfamily J, member 5 /FL=gb:D50134.1 D50134 potassium inwardly-rectifying channel, subfamily J, member 5 KCNJ5 3762 NM_000890 /// XM_005271543 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // traceable author statement 211305_x_at U56236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U56236.1 /DEF=Human Fc alpha receptor b mRNA, complete cds. /FEA=mRNA /PROD=FcalphaRb /DB_XREF=gi:1326228 /UG=Hs.193122 Fc fragment of IgA, receptor for /FL=gb:U56236.1 U56236 Fc fragment of IgA, receptor for FCAR 2204 NM_002000 /// NM_133269 /// NM_133271 /// NM_133272 /// NM_133273 /// NM_133274 /// NM_133277 /// NM_133278 /// NM_133279 /// NM_133280 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019862 // IgA binding // inferred from electronic annotation 211306_s_at U56237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U56237.1 /DEF=Human Fc alpha receptor b deltaS2 mRNA, complete cds. /FEA=mRNA /PROD=FcalphaRbdeltaS2 /DB_XREF=gi:1326230 /UG=Hs.193122 Fc fragment of IgA, receptor for /FL=gb:U56237.1 U56237 Fc fragment of IgA, receptor for FCAR 2204 NM_002000 /// NM_133269 /// NM_133271 /// NM_133272 /// NM_133273 /// NM_133274 /// NM_133277 /// NM_133278 /// NM_133279 /// NM_133280 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019862 // IgA binding // inferred from electronic annotation 211307_s_at U43677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43677.1 /DEF=Human Fc alpha receptor, splice variant FcalphaR a.3 (CD89) mRNA, complete cds. /FEA=mRNA /GEN=CD89 /PROD=Fc alpha receptor /DB_XREF=gi:1439557 /UG=Hs.193122 Fc fragment of IgA, receptor for /FL=gb:U43677.1 gb:D87854.1 gb:D87856.1 U43677 Fc fragment of IgA, receptor for FCAR 2204 NM_002000 /// NM_133269 /// NM_133271 /// NM_133272 /// NM_133273 /// NM_133274 /// NM_133277 /// NM_133278 /// NM_133279 /// NM_133280 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019862 // IgA binding // inferred from electronic annotation 211310_at AB004818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB004818.1 /DEF=Homo sapiens mRNA for ENX-2, complete cds. /FEA=mRNA /PROD=ENX-2 /DB_XREF=gi:2934699 /UG=Hs.194669 enhancer of zeste (Drosophila) homolog 1 /FL=gb:AB004818.1 AB004818 enhancer of zeste 1 polycomb repressive complex 2 subunit EZH1 2145 NM_001991 /// XM_005257144 /// XM_005257145 /// XM_005257146 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from electronic annotation 211312_s_at AB034725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB034725.1 /DEF=Homo sapiens mRNA for WISP-1 variant, complete cds. /FEA=mRNA /PROD=WISP-1 variant /DB_XREF=gi:11176998 /UG=Hs.194680 WNT1 inducible signaling pathway protein 1 /FL=gb:AB034725.1 AB034725 WNT1 inducible signaling pathway protein 1 WISP1 8840 NM_001204869 /// NM_001204870 /// NM_003882 /// NM_080838 /// NR_037944 /// XM_006716680 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation 211313_s_at AB032253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB032253.1 /DEF=Homo sapiens BAZ1B mRNA for bromodomain adjacent to zinc finger domain 1B, complete cds. /FEA=mRNA /GEN=BAZ1B /PROD=bromodomain adjacent to zinc finger domain 1B /DB_XREF=gi:6683495 /UG=Hs.194688 bromodomain adjacent to zinc finger domain, 1B /FL=gb:AB032253.1 AB032253 bromodomain adjacent to zinc finger domain, 1B BAZ1B 9031 NM_023005 /// NM_032408 /// XM_005250683 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay /// 0071884 // vitamin D receptor activator activity // inferred from electronic annotation 211314_at AB012043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012043.1 /DEF=Homo sapiens mRNA for NBR13, complete cds. /FEA=mRNA /PROD=NBR13 /DB_XREF=gi:4115531 /UG=Hs.194746 calcium channel, voltage-dependent, alpha 1G subunit /FL=gb:AB012043.1 AB012043 calcium channel, voltage-dependent, T type, alpha 1G subunit CACNA1G 8913 NM_001256324 /// NM_001256325 /// NM_001256326 /// NM_001256327 /// NM_001256328 /// NM_001256329 /// NM_001256330 /// NM_001256331 /// NM_001256332 /// NM_001256333 /// NM_001256334 /// NM_001256359 /// NM_001256360 /// NM_001256361 /// NM_018896 /// NM_198376 /// NM_198377 /// NM_198378 /// NM_198379 /// NM_198380 /// NM_198382 /// NM_198383 /// NM_198384 /// NM_198385 /// NM_198386 /// NM_198387 /// NM_198388 /// NM_198396 /// NM_198397 /// NR_046054 /// NR_046055 /// NR_046056 /// NR_046057 /// NR_046058 /// XM_006722160 /// XM_006722161 0001508 // action potential // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010045 // response to nickel cation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 211315_s_at AB012043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012043.1 /DEF=Homo sapiens mRNA for NBR13, complete cds. /FEA=mRNA /PROD=NBR13 /DB_XREF=gi:4115531 /UG=Hs.194746 calcium channel, voltage-dependent, alpha 1G subunit /FL=gb:AB012043.1 AB012043 calcium channel, voltage-dependent, T type, alpha 1G subunit CACNA1G 8913 NM_001256324 /// NM_001256325 /// NM_001256326 /// NM_001256327 /// NM_001256328 /// NM_001256329 /// NM_001256330 /// NM_001256331 /// NM_001256332 /// NM_001256333 /// NM_001256334 /// NM_001256359 /// NM_001256360 /// NM_001256361 /// NM_018896 /// NM_198376 /// NM_198377 /// NM_198378 /// NM_198379 /// NM_198380 /// NM_198382 /// NM_198383 /// NM_198384 /// NM_198385 /// NM_198386 /// NM_198387 /// NM_198388 /// NM_198396 /// NM_198397 /// NR_046054 /// NR_046055 /// NR_046056 /// NR_046057 /// NR_046058 /// XM_006722160 /// XM_006722161 0001508 // action potential // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010045 // response to nickel cation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 211316_x_at AF009616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009616.1 /DEF=Homo sapiens FLAME-1 mRNA, complete cds. /FEA=mRNA /PROD=FLAME-1 /DB_XREF=gi:2429153 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF009616.1 AF009616 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 211317_s_at AF041461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF041461.1 /DEF=Homo sapiens I-FLICE isoform 4 mRNA, complete cds. /FEA=mRNA /PROD=I-FLICE isoform 4 /DB_XREF=gi:2827295 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF041461.1 AF041461 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 211318_s_at U85943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85943.1 /DEF=Homo sapiens mRNA-associated protein mrnp41 mRNA, complete cds. /FEA=mRNA /PROD=mRNA-associated protein mrnp41 /DB_XREF=gi:2231591 /UG=Hs.196209 RAE1 (RNA export 1, S.pombe) homolog /FL=gb:U85943.1 U85943 ribonucleic acid export 1 RAE1 8480 NM_001015885 /// NM_003610 /// XM_005260582 /// XM_005260583 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005640 // nuclear outer membrane // traceable author statement /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 211319_at U85943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85943.1 /DEF=Homo sapiens mRNA-associated protein mrnp41 mRNA, complete cds. /FEA=mRNA /PROD=mRNA-associated protein mrnp41 /DB_XREF=gi:2231591 /UG=Hs.196209 RAE1 (RNA export 1, S.pombe) homolog /FL=gb:U85943.1 U85943 ribonucleic acid export 1 RAE1 8480 NM_001015885 /// NM_003610 /// XM_005260582 /// XM_005260583 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005640 // nuclear outer membrane // traceable author statement /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003723 // RNA binding // traceable author statement /// 0008017 // microtubule binding // inferred from sequence or structural similarity 211320_s_at U71075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71075.1 /DEF=Homo sapiens protein tyrosine phosphatase receptor omicron (PTPRO) mRNA, complete cds. /FEA=mRNA /GEN=PTPRO /PROD=protein tyrosine phosphatase receptor omicron /DB_XREF=gi:1890659 /UG=Hs.19718 protein tyrosine phosphatase, receptor type, U /FL=gb:U71075.1 U71075 protein tyrosine phosphatase, receptor type, U PTPRU 10076 NM_001195001 /// NM_005704 /// NM_133177 /// NM_133178 /// XM_006710269 /// XM_006710270 /// XM_006710271 /// XM_006710272 /// XM_006710273 0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 211322_s_at AF047004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF047004.1 /DEF=Homo sapiens dimethylglycine dehydrogenase-like protein isoform 1 mRNA, complete cds. /FEA=mRNA /PROD=dimethylglycine dehydrogenase-like proteinisoform 1 /DB_XREF=gi:4235221 /UG=Hs.198003 sarcosine dehydrogenase /FL=gb:AF047004.1 AF047004 sarcosine dehydrogenase SARDH 1757 NM_001134707 /// NM_007101 /// XM_005272170 /// XM_006716990 /// XM_006716991 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008480 // sarcosine dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 211323_s_at L38019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L38019.1 /DEF=Homo sapiens (clone HUM-IP3R1) inositol 1,4,5-trisphosphate receptor type 1 mRNA, complete cds. /FEA=mRNA /GEN=ITPR1 /PROD=inositol 1,4,5-trisphosphate receptor type 1 /DB_XREF=gi:1464750 /UG=Hs.198443 inositol 1,4,5-triphosphate receptor, type 1 /FL=gb:L38019.1 L38019 inositol 1,4,5-trisphosphate receptor, type 1 ITPR1 3708 NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity 211324_s_at AL136868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136868.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P144 (from clone DKFZp434P144); complete cds. /FEA=mRNA /GEN=DKFZp434P144 /PROD=hypothetical protein /DB_XREF=gi:12053240 /UG=Hs.199179 RAN binding protein 2 /FL=gb:AL136868.1 AL136868 RANBP2-like and GRIP domain containing 3 /// RANBP2-like and GRIP domain containing 4 /// RANBP2-like and GRIP domain containing 5 /// RANBP2-like and GRIP domain containing 6 /// RANBP2-like and GRIP domain containing 8 RGPD3 /// RGPD4 /// RGPD5 /// RGPD6 /// RGPD8 84220 /// 285190 /// 653489 /// 727851 /// 729540 NM_001037866 /// NM_001123363 /// NM_001144013 /// NM_001164463 /// NM_005054 /// NM_032260 /// NM_182588 /// XM_005263747 /// XM_005263748 /// XM_005263753 /// XM_005263755 /// XM_005263756 /// XM_005263819 /// XM_005263820 /// XM_005263821 /// XM_005263822 /// XM_006712454 /// XM_006712708 /// XM_006712794 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // non-traceable author statement 211325_x_at U72518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U72518.1 /DEF=Human destrin-2 pseudogene mRNA, complete cds. /FEA=mRNA /PROD=destrin-2 /DB_XREF=gi:1673523 /UG=Hs.199299 Human destrin-2 pseudogene mRNA, complete cds /FL=gb:U72518.1 U72518 destrin (actin depolymerizing factor) pseudogene 2 DSTNP2 171220 NR_033796 211326_x_at AF150664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF150664.1 /DEF=Homo sapiens hemochromatosis splice variant delE3,intron3ins,intron4ins (HFE) mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variantdelE3,intron3ins,intron4ins /DB_XREF=gi:11093525 /UG=Hs.20019 hemochromatosis /FL=gb:AF150664.1 AF150664 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211327_x_at AF149804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF149804.1 /DEF=Homo sapiens hemochromatosis protein splice variant 562-878del (HFE) mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis protein splice variant562-878del /DB_XREF=gi:11093523 /UG=Hs.20019 hemochromatosis /FL=gb:AF149804.1 AF149804 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211328_x_at AF144244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF144244.1 /DEF=Homo sapiens hemochromatosis splice variant 388-2283del,intron6ins mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant388-2283del,intron6ins /DB_XREF=gi:11094328 /UG=Hs.20019 hemochromatosis /FL=gb:AF144244.1 gb:AF144245.1 AF144244 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211329_x_at AF115264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF115264.1 /DEF=Homo sapiens hemochromatosis splice variant delE3-7 (HFE) mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant delE3-7 /DB_XREF=gi:11094312 /UG=Hs.20019 hemochromatosis /FL=gb:AF115264.1 AF115264 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211330_s_at AF144242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF144242.1 /DEF=Homo sapiens hemochromatosis splice variant delE3 mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant delE3 /DB_XREF=gi:11094324 /UG=Hs.20019 hemochromatosis /FL=gb:AF144242.1 AF144242 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211331_x_at AF144243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF144243.1 /DEF=Homo sapiens hemochromatosis splice variant 495-2314del mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant 495-2314del /DB_XREF=gi:11094326 /UG=Hs.20019 hemochromatosis /FL=gb:AF144243.1 AF144243 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211332_x_at AF144241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF144241.1 /DEF=Homo sapiens hemochromatosis splice variant 861-2305del mRNA, complete cds. /FEA=mRNA /GEN=HFE /PROD=hemochromatosis splice variant 861-2305del /DB_XREF=gi:11094322 /UG=Hs.20019 hemochromatosis /FL=gb:AF144239.1 gb:AF144241.1 AF144241 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211333_s_at AF288573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288573.1 /DEF=Homo sapiens FasL isoform mRNA, complete cds. /FEA=mRNA /PROD=FasL isoform /DB_XREF=gi:12597288 /UG=Hs.2007 tumor necrosis factor (ligand) superfamily, member 6 /FL=gb:AF288573.1 AF288573 Fas ligand (TNF superfamily, member 6) FASLG 356 NM_000639 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from genetic interaction /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0048388 // endosomal lumen acidification // inferred from electronic annotation /// 0070231 // T cell apoptotic process // inferred from direct assay /// 0070265 // necrotic cell death // inferred from direct assay /// 0070266 // necroptotic process // inferred from direct assay /// 0070848 // response to growth factor // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060205 // cytoplasmic membrane-bounded vesicle lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211334_at BC005241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005241.1 /DEF=Homo sapiens, clone MGC:12269, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12269) /DB_XREF=gi:13528887 /UG=Hs.202379 meiotic recombination (S. cerevisiae) 11 homolog B /FL=gb:BC005241.1 BC005241 MRE11 meiotic recombination 11 homolog A (S. cerevisiae) MRE11A 4361 NM_005590 /// NM_005591 /// XM_005274007 /// XM_005274008 /// XM_006718842 0000019 // regulation of mitotic recombination // traceable author statement /// 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // not recorded /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006289 // nucleotide-excision repair // not recorded /// 0006302 // double-strand break repair // not recorded /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // not recorded /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // not recorded /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030870 // Mre11 complex // inferred from direct assay /// 0030870 // Mre11 complex // non-traceable author statement /// 0035861 // site of double-strand break // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // traceable author statement /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // traceable author statement /// 0004519 // endonuclease activity // not recorded /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation 211336_x_at AF009007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009007.1 /DEF=Homo sapiens immunoglobulin-like transcript 2c mRNA, complete cds. /FEA=mRNA /PROD=immunoglobulin-like transcript 2c /DB_XREF=gi:2660705 /UG=Hs.204040 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 /FL=gb:AF009007.1 AF009007 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 LILRB1 10859 NM_001081637 /// NM_001081638 /// NM_001081639 /// NM_001278398 /// NM_001278399 /// NM_006669 /// NR_103518 /// XM_005277047 /// XM_006726246 /// XM_006726247 /// XM_006726248 /// XM_006726249 /// XM_006726250 /// XM_006726251 /// XM_006726252 /// XM_006726281 /// XM_006726282 /// XM_006726283 /// XM_006726284 /// XM_006726285 /// XM_006726286 /// XM_006726287 /// XR_254255 /// XR_431086 /// XR_431087 /// XR_431094 /// XR_431095 /// XR_431096 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002309 // T cell proliferation involved in immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // non-traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014063 // negative regulation of serotonin secretion // inferred from direct assay /// 0031623 // receptor internalization // traceable author statement /// 0032609 // interferon-gamma production // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032945 // negative regulation of mononuclear cell proliferation // inferred from direct assay /// 0035548 // negative regulation of interferon-beta secretion // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045077 // negative regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0045953 // negative regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0046636 // negative regulation of alpha-beta T cell activation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0072643 // interferon-gamma secretion // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001180 // negative regulation of interleukin-10 secretion // inferred from direct assay /// 2001183 // negative regulation of interleukin-12 secretion // inferred from direct assay /// 2001186 // negative regulation of CD8-positive, alpha-beta T cell activation // inferred from direct assay /// 2001189 // negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from direct assay /// 2001193 // positive regulation of gamma-delta T cell activation involved in immune response // inferred from direct assay /// 2001199 // negative regulation of dendritic cell differentiation // inferred from mutant phenotype /// 2001202 // negative regulation of transforming growth factor-beta secretion // inferred from direct assay /// 2001205 // negative regulation of osteoclast development // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008157 // protein phosphatase 1 binding // inferred from physical interaction /// 0030107 // HLA-A specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0032393 // MHC class I receptor activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from mutant phenotype /// 0042288 // MHC class I protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211337_s_at BC000966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000966.2 /DEF=Homo sapiens, Similar to gamma tubulin ring complex protein (76p gene), clone MGC:4930, mRNA, complete cds. /FEA=mRNA /PROD=Similar to gamma tubulin ring complex protein(76p gene) /DB_XREF=gi:12803021 /UG=Hs.20621 gamma tubulin ring complex protein (76p gene) /FL=gb:BC000966.2 BC000966 tubulin, gamma complex associated protein 4 TUBGCP4 27229 NM_001286414 /// NM_014444 /// XR_243092 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // non-traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // non-traceable author statement /// 0015630 // microtubule cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005200 // structural constituent of cytoskeleton // non-traceable author statement 211338_at M54886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M54886.1 /DEF=Human interferon-alpha mRNA, complete cds. /FEA=mRNA /GEN=IFNA /PROD=interferon /DB_XREF=gi:186498 /UG=Hs.211575 interferon, alpha 2 /FL=gb:NM_000605.2 gb:M54886.1 M54886 interferon, alpha 2 IFNA2 3440 NM_000605 0006915 // apoptotic process // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045581 // negative regulation of T cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2000552 // negative regulation of T-helper 2 cell cytokine production // inferred from direct assay /// 2000663 // negative regulation of interleukin-5 secretion // inferred from direct assay /// 2000666 // negative regulation of interleukin-13 secretion // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211339_s_at D13720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D13720.1 /DEF=Homo sapiens mRNA for ITK, complete cds. /FEA=mRNA /PROD=ITK /DB_XREF=gi:399657 /UG=Hs.211576 IL2-inducible T-cell kinase /FL=gb:D13720.1 D13720 IL2-inducible T-cell kinase ITK 3702 NM_005546 0001816 // cytokine production // inferred from sequence or structural similarity /// 0001865 // NK T cell differentiation // inferred from electronic annotation /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0032633 // interleukin-4 production // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211340_s_at M28882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M28882.1 /DEF=Human MUC18 glycoprotein mRNA, complete cds. /FEA=mRNA /PROD=MUC18 glycoprotein /DB_XREF=gi:529723 /UG=Hs.211579 melanoma adhesion molecule /FL=gb:M28882.1 M28882 melanoma cell adhesion molecule /// microRNA 6756 MCAM /// MIR6756 4162 /// 102465453 NM_006500 /// NR_106814 /// XM_005271551 /// XM_005271552 /// XM_006718836 /// XM_006718837 /// XM_006718838 0003094 // glomerular filtration // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0061042 // vascular wound healing // inferred from expression pattern 0005886 // plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211341_at L20433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20433.1 /DEF=Human octamer binding transcription factor 1 (OTF1) mRNA, complete cds. /FEA=mRNA /GEN=OTF1 /PROD=octamer binding transcription factor 1 /DB_XREF=gi:418015 /UG=Hs.211588 POU domain, class 4, transcription factor 1 /FL=gb:L20433.1 L20433 POU class 4 homeobox 1 POU4F1 5457 NM_006237 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0003223 // ventricular compact myocardium morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007498 // mesoderm development // inferred from electronic annotation /// 0021535 // cell migration in hindbrain // inferred from electronic annotation /// 0021559 // trigeminal nerve development // inferred from sequence or structural similarity /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0021986 // habenula development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048665 // neuron fate specification // inferred from sequence or structural similarity /// 0048880 // sensory system development // inferred from sequence or structural similarity /// 0048934 // peripheral nervous system neuron differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051355 // proprioception involved in equilibrioception // inferred from electronic annotation /// 0060384 // innervation // traceable author statement 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211342_x_at BC004354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004354.1 /DEF=Homo sapiens, trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit), clone MGC:3120, mRNA, complete cds. /FEA=mRNA /PROD=trinucleotide repeat containing 11(THR-associated protein, 230 kDa subunit) /DB_XREF=gi:13279313 /UG=Hs.211607 trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) /FL=gb:BC004354.1 BC004354 mediator complex subunit 12 MED12 9968 NM_005120 /// XM_005262317 /// XM_005262319 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090245 // axis elongation involved in somitogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 211343_s_at M33653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33653.1 /DEF=Human (clones HT-125,133) alpha-2 type IV collagen (COL4A2) mRNA, complete cds. /FEA=mRNA /GEN=COL4A2 /PROD=alpha-2 type IV collagen /DB_XREF=gi:180828 /UG=Hs.211933 collagen, type XIII, alpha 1 /FL=gb:M33653.1 M33653 collagen, type XIII, alpha 1 COL13A1 1305 NM_001130103 /// NM_005203 /// NM_080798 /// NM_080799 /// NM_080800 /// NM_080801 /// NM_080802 /// NM_080803 /// NM_080804 /// NM_080805 /// NM_080806 /// NM_080807 /// NM_080808 /// NM_080809 /// NM_080810 /// NM_080811 /// NM_080812 /// NM_080813 /// NM_080814 /// NM_080815 /// XM_006717632 0001503 // ossification // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from physical interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from expression pattern /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005600 // collagen type XIII trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay 211345_x_at AF119850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119850.1 /DEF=Homo sapiens PRO1608 mRNA, complete cds. /FEA=mRNA /PROD=PRO1608 /DB_XREF=gi:7770136 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma /FL=gb:AF119850.1 AF119850 eukaryotic translation elongation factor 1 gamma /// microRNA 3654 EEF1G /// MIR3654 1937 /// 100500804 NM_001404 /// NR_037427 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211347_at AF064105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064105.2 /DEF=Homo sapiens Cdc14B3 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14B3 phosphatase /DB_XREF=gi:5706723 /UG=Hs.22116 CDC14 (cell division cycle 14, S. cerevisiae) homolog B /FL=gb:AF064105.2 AF064105 cell division cycle 14B CDC14B 8555 NM_001077181 /// NM_003671 /// NM_033331 /// NM_033332 /// XM_005252286 /// XM_005252287 /// XM_005252288 /// XR_242602 /// XR_242603 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 211348_s_at AF064105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064105.2 /DEF=Homo sapiens Cdc14B3 phosphatase mRNA, complete cds. /FEA=mRNA /PROD=Cdc14B3 phosphatase /DB_XREF=gi:5706723 /UG=Hs.22116 CDC14 (cell division cycle 14, S. cerevisiae) homolog B /FL=gb:AF064105.2 AF064105 cell division cycle 14B CDC14B 8555 NM_001077181 /// NM_003671 /// NM_033331 /// NM_033332 /// XM_005252286 /// XM_005252287 /// XM_005252288 /// XR_242602 /// XR_242603 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 211349_at AB001328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB001328.1 /DEF=Homo sapiens mRNA for pH-sensing regulatory factor of peptide transporter, complete cds. /FEA=mRNA /GEN=hPEPT1-RF /PROD=pH-sensing regulatory factor of peptidetransporter /DB_XREF=gi:2506042 /UG=Hs.2217 solute carrier family 15 (oligopeptide transporter), member 1 /FL=gb:AB001328.1 AB001328 solute carrier family 15 (oligopeptide transporter), member 1 SLC15A1 6564 NM_005073 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006857 // oligopeptide transport // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0015833 // peptide transport // non-traceable author statement /// 0015992 // proton transport // traceable author statement /// 0035672 // oligopeptide transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005427 // proton-dependent oligopeptide secondary active transmembrane transporter activity // inferred from electronic annotation /// 0015198 // oligopeptide transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015333 // peptide:proton symporter activity // traceable author statement 211350_s_at AB016900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016900.1 /DEF=Homo sapiens HGC6.1.2 mRNA, complete cds. /FEA=mRNA /GEN=HGC6.1.2 /DB_XREF=gi:5006256 /UG=Hs.225962 HGC6.1.1 protein /FL=gb:AB016900.1 AB016900 KIF25 antisense RNA 1 KIF25-AS1 100505879 NM_014354 /// NR_103750 211351_at AB016900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016900.1 /DEF=Homo sapiens HGC6.1.2 mRNA, complete cds. /FEA=mRNA /GEN=HGC6.1.2 /DB_XREF=gi:5006256 /UG=Hs.225962 HGC6.1.1 protein /FL=gb:AB016900.1 AB016900 KIF25 antisense RNA 1 KIF25-AS1 100505879 NM_014354 /// NR_103750 211352_s_at U80737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U80737.1 /DEF=Homo sapiens CAGH16 mRNA, complete cds. /FEA=mRNA /GEN=CAGH16 /PROD=CAGH16 /DB_XREF=gi:2565049 /UG=Hs.225977 nuclear receptor coactivator 3 /FL=gb:U80737.1 U80737 nuclear receptor coactivator 3 NCOA3 8202 NM_001174087 /// NM_001174088 /// NM_006534 /// NM_181659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035624 // receptor transactivation // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060713 // labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 211353_at AB031547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB031547.1 /DEF=Homo sapiens mRNA for retina specific protein PAL, complete cds. /FEA=mRNA /GEN=PAL /PROD=retina specific protein PAL /DB_XREF=gi:7861534 /UG=Hs.226000 DKFZP434K091 protein /FL=gb:AB031547.1 AB031547 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 LRIT1 26103 NM_015613 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 211354_s_at U52913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U52913.1 /DEF=Human B219OB receptor isoform HuB219.2 precursor mRNA, complete cds. /FEA=mRNA /PROD=B219OB receptor isoform HuB219.2 precursor /DB_XREF=gi:1279902 /UG=Hs.226627 leptin receptor /FL=gb:U52913.1 U52913 leptin receptor /// leptin receptor overlapping transcript LEPR /// LEPROT 3953 /// 54741 NM_001003679 /// NM_001003680 /// NM_001198681 /// NM_001198683 /// NM_001198687 /// NM_001198688 /// NM_001198689 /// NM_002303 /// NM_017526 0006112 // energy reserve metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 211355_x_at U52914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U52914.1 /DEF=Human B219OB receptor isoform HuB219.3 precursor mRNA, complete cds. /FEA=mRNA /PROD=B219OB receptor isoform HuB219.3 precursor /DB_XREF=gi:1279904 /UG=Hs.226627 leptin receptor /FL=gb:U52914.1 U52914 leptin receptor /// leptin receptor overlapping transcript LEPR /// LEPROT 3953 /// 54741 NM_001003679 /// NM_001003680 /// NM_001198681 /// NM_001198683 /// NM_001198687 /// NM_001198688 /// NM_001198689 /// NM_002303 /// NM_017526 0006112 // energy reserve metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 211356_x_at U66495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66495.1 /DEF=Human leptin receptor splice variant form 6.4 mRNA, complete cds. /FEA=mRNA /PROD=leptin receptor /DB_XREF=gi:1519389 /UG=Hs.226627 leptin receptor /FL=gb:U66495.1 U66495 leptin receptor /// leptin receptor overlapping transcript LEPR /// LEPROT 3953 /// 54741 NM_001003679 /// NM_001003680 /// NM_001198681 /// NM_001198683 /// NM_001198687 /// NM_001198688 /// NM_001198689 /// NM_002303 /// NM_017526 0006112 // energy reserve metabolic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 211357_s_at BC005314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005314.1 /DEF=Homo sapiens, Similar to haptoglobin, clone MGC:12390, mRNA, complete cds. /FEA=mRNA /PROD=Similar to haptoglobin /DB_XREF=gi:13529061 /UG=Hs.234234 aldolase B, fructose-bisphosphate /FL=gb:BC005314.1 BC005314 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 211358_s_at AF234161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF234161.1 /DEF=Homo sapiens nuclear protein NP94b (NP94) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=NP94 /PROD=nuclear protein NP94b /DB_XREF=gi:7188807 /UG=Hs.23476 Cip1-interacting zinc finger protein /FL=gb:AF234161.1 AF234161 CDKN1A interacting zinc finger protein 1 CIZ1 25792 NM_001131015 /// NM_001131016 /// NM_001131017 /// NM_001131018 /// NM_001257975 /// NM_001257976 /// NM_012127 /// XM_005251886 /// XM_005251887 /// XM_005251888 /// XM_005251889 /// XM_005251890 /// XM_005251891 /// XM_005251892 /// XM_005251893 /// XM_006717036 /// XM_006717037 /// XM_006717038 /// XM_006717039 /// XM_006717040 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from electronic annotation /// 0051658 // maintenance of nucleus location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211359_s_at U12569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U12569.1 /DEF=Human mu opioid receptor variant (MOR1) mRNA, complete cds. /FEA=mRNA /GEN=MOR1 /PROD=mu opioid receptor variant /DB_XREF=gi:607911 /UG=Hs.2353 opioid receptor, mu 1 /FL=gb:U12569.1 U12569 opioid receptor, mu 1 OPRM1 4988 NM_000914 /// NM_001008503 /// NM_001008504 /// NM_001008505 /// NM_001145279 /// NM_001145280 /// NM_001145281 /// NM_001145282 /// NM_001145283 /// NM_001145284 /// NM_001145285 /// NM_001145286 /// NM_001145287 /// NM_001285522 /// NM_001285523 /// NM_001285524 /// NM_001285526 /// NM_001285527 /// NM_001285528 /// NR_104348 /// NR_104349 /// NR_104350 /// NR_104351 /// XM_006715496 /// XM_006715497 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from mutant phenotype /// 0007600 // sensory perception // non-traceable author statement /// 0007610 // behavior // non-traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0033554 // cellular response to stress // inferred from mutant phenotype /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0048149 // behavioral response to ethanol // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from mutant phenotype /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0061358 // negative regulation of Wnt protein secretion // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0071315 // cellular response to morphine // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0004979 // beta-endorphin receptor activity // inferred from mutant phenotype /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0038047 // morphine receptor activity // inferred from sequence or structural similarity 211360_s_at AB012610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012610.1 /DEF=Homo sapiens TIPR mRNA for inositol 1,4,5-trisphosphate receptor type 2, complete cds. /FEA=mRNA /GEN=TIPR /PROD=inositol 1,4,5-trisphosphate receptor type 2 /DB_XREF=gi:3786317 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:AB012610.1 AB012610 inositol 1,4,5-trisphosphate receptor, type 2 ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 211361_s_at AJ001696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001696.2 /DEF=Homo sapiens mRNA for hurpin, clone R7-1.1. /FEA=mRNA /GEN=PI13 /PROD=hurpin /DB_XREF=gi:6018505 /UG=Hs.241407 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 /FL=gb:AF169949.1 gb:NM_012397.1 AJ001696 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 211362_s_at AF169949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF169949.1 /DEF=Homo sapiens headpin mRNA, complete cds. /FEA=mRNA /PROD=headpin /DB_XREF=gi:5911368 /UG=Hs.241407 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 /FL=gb:AF169949.1 gb:NM_012397.1 AF169949 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 211363_s_at AF109294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109294.1 /DEF=Homo sapiens hypothetical methylthioadenosine phosphorylase fusion protein mRNA, complete cds. /FEA=mRNA /PROD=hypothetical methylthioadenosine phosphorylasefusion protein /DB_XREF=gi:4378719 /UG=Hs.241436 Homo sapiens hypothetical methylthioadenosine phosphorylase fusion protein mRNA, complete cds /FL=gb:AF109294.1 AF109294 methylthioadenosine phosphorylase MTAP 4507 NM_002451 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0017061 // S-methyl-5-thioadenosine phosphorylase activity // traceable author statement 211364_at AF109294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF109294.1 /DEF=Homo sapiens hypothetical methylthioadenosine phosphorylase fusion protein mRNA, complete cds. /FEA=mRNA /PROD=hypothetical methylthioadenosine phosphorylasefusion protein /DB_XREF=gi:4378719 /UG=Hs.241436 Homo sapiens hypothetical methylthioadenosine phosphorylase fusion protein mRNA, complete cds /FL=gb:AF109294.1 AF109294 methylthioadenosine phosphorylase MTAP 4507 NM_002451 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0017061 // S-methyl-5-thioadenosine phosphorylase activity // traceable author statement 211365_s_at AF152480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152480.1 /DEF=Homo sapiens protocadherin alpha 2 short form protein (PCDH-alpha2) variable region sequence, complete cds. /FEA=mRNA /GEN=PCDH-alpha2 /PROD=protocadherin alpha 2 short form protein /DB_XREF=gi:5457008 /UG=Hs.247741 protocadherin alpha 2 /FL=gb:AF152480.1 AF152480 protocadherin alpha 2 PCDHA2 56146 NM_018905 /// NM_031495 /// NM_031496 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 211366_x_at U13698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13698.1 /DEF=Human interleukin 1-beta converting enzyme isoform gamma (IL1BCE) mRNA, complete cds. /FEA=mRNA /GEN=IL1BCE /PROD=interleukin 1-beta converting enzyme isoformgamma /DB_XREF=gi:717041 /UG=Hs.2490 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) /FL=gb:U13698.1 U13698 caspase 1, apoptosis-related cysteine peptidase CASP1 834 NM_001223 /// NM_001257118 /// NM_001257119 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 /// XM_006718924 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0051882 // mitochondrial depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070269 // pyroptosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0097194 // execution phase of apoptosis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0072557 // IPAF inflammasome complex // not recorded /// 0072557 // IPAF inflammasome complex // inferred from sequence or structural similarity /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 211367_s_at U13699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13699.1 /DEF=Human interleukin 1-beta converting enzyme isoform delta (IL1BCE) mRNA, complete cds. /FEA=mRNA /GEN=IL1BCE /PROD=Interleukin 1-beta converting enzyme isoformdelta /DB_XREF=gi:717043 /UG=Hs.2490 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) /FL=gb:U13699.1 U13699 caspase 1, apoptosis-related cysteine peptidase CASP1 834 NM_001223 /// NM_001257118 /// NM_001257119 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 /// XM_006718924 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0051882 // mitochondrial depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070269 // pyroptosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0097194 // execution phase of apoptosis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0072557 // IPAF inflammasome complex // not recorded /// 0072557 // IPAF inflammasome complex // inferred from sequence or structural similarity /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 211368_s_at U13700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U13700.1 /DEF=Human interleukin 1-beta converting enzyme isoform epsilon (IL1BCE) mRNA, complete cds. /FEA=mRNA /GEN=IL1BCE /PROD=Interleukin 1-beta converting enzyme isoformepsilon /DB_XREF=gi:717045 /UG=Hs.2490 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) /FL=gb:U13700.1 U13700 caspase 1, apoptosis-related cysteine peptidase CASP1 834 NM_001223 /// NM_001257118 /// NM_001257119 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 /// XM_006718924 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050717 // positive regulation of interleukin-1 alpha secretion // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0051882 // mitochondrial depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070269 // pyroptosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0097194 // execution phase of apoptosis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0072557 // IPAF inflammasome complex // not recorded /// 0072557 // IPAF inflammasome complex // inferred from sequence or structural similarity /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 211369_at AF116689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116689.1 /DEF=Homo sapiens PRO2168 mRNA, complete cds. /FEA=mRNA /PROD=PRO2168 /DB_XREF=gi:7959876 /UG=Hs.249715 Homo sapiens PRO2168 mRNA, complete cds /FL=gb:AF116689.1 AF116689 211370_s_at U71088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71088.1 /DEF=Human MAP kinase kinase MEK5c mRNA, complete cds. /FEA=mRNA /PROD=MAP kinase kinase MEK5c /DB_XREF=gi:1616780 /UG=Hs.250870 mitogen-activated protein kinase kinase 5 /FL=gb:U71088.1 U71088 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211371_at U71088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U71088.1 /DEF=Human MAP kinase kinase MEK5c mRNA, complete cds. /FEA=mRNA /PROD=MAP kinase kinase MEK5c /DB_XREF=gi:1616780 /UG=Hs.250870 mitogen-activated protein kinase kinase 5 /FL=gb:U71088.1 U71088 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211372_s_at U64094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U64094.1 /DEF=Human soluble type II interleukin-1 receptor mRNA, complete cds. /FEA=mRNA /PROD=soluble type II interleukin-1 receptor /DB_XREF=gi:1488065 /UG=Hs.25333 interleukin 1 receptor, type II /FL=gb:U64094.1 U64094 interleukin 1 receptor, type II IL1R2 7850 NM_001261419 /// NM_004633 /// NM_173343 /// NR_048564 /// XM_006712733 /// XM_006712734 /// XM_006712735 /// XM_006712736 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004908 // interleukin-1 receptor activity // traceable author statement /// 0004910 // interleukin-1, Type II, blocking receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211373_s_at U34349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U34349.1 /DEF=Human seven trans-membrane domain protein (AD3LPAD5) mRNA, complete cds. /FEA=mRNA /GEN=AD3LPAD5 /PROD=seven trans-membrane domain protein AD3LPAD5 /DB_XREF=gi:1079575 /UG=Hs.25363 presenilin 2 (Alzheimer disease 4) /FL=gb:U34349.1 U34349 presenilin 2 PSEN2 5664 NM_000447 /// NM_012486 /// XM_005273199 0001666 // response to hypoxia // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030426 // growth cone // not recorded /// 0031594 // neuromuscular junction // not recorded /// 0035253 // ciliary rootlet // not recorded /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004175 // endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211374_x_at AF116715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116715.1 /DEF=Homo sapiens PRO2829 mRNA, complete cds. /FEA=mRNA /PROD=PRO2829 /DB_XREF=gi:7959928 /UG=Hs.256256 Homo sapiens PRO2829 mRNA, complete cds /FL=gb:AF116715.1 AF116715 0005576 // extracellular region // inferred from electronic annotation 211375_s_at AF141870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF141870.1 /DEF=Homo sapiens translational control protein 80 mRNA, complete cds. /FEA=mRNA /PROD=translational control protein 80 /DB_XREF=gi:5006601 /UG=Hs.256583 interleukin enhancer binding factor 3, 90kD /FL=gb:AF141870.1 AF141870 interleukin enhancer binding factor 3, 90kDa ILF3 3609 NM_001137673 /// NM_004516 /// NM_012218 /// NM_017620 /// NM_153464 /// XM_005259895 /// XM_006722742 0000279 // M phase // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211376_s_at BC005212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005212.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20003, clone MGC:12228, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20003 /DB_XREF=gi:13528824 /UG=Hs.258798 hypothetical protein FLJ20003 /FL=gb:BC005212.1 BC005212 non-SMC element 4 homolog A (S. cerevisiae) NSMCE4A 54780 NM_001167865 /// NM_017615 /// XM_005269928 /// XM_005269929 /// XM_005269930 /// XR_428706 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030915 // Smc5-Smc6 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211377_x_at AF320053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF320053.1 /DEF=Homo sapiens N-MYC mRNA, complete cds. /FEA=mRNA /PROD=N-MYC /DB_XREF=gi:11692795 /UG=Hs.25960 v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived /FL=gb:AF320053.1 AF320053 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog MYCN 4613 NM_001293228 /// NM_001293231 /// NM_001293233 /// NM_005378 /// XM_006711886 0001502 // cartilage condensation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 211378_x_at BC001224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001224.1 /DEF=Homo sapiens, clone MGC:982, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:982) /DB_XREF=gi:12654762 /UG=Hs.267690 KIAA1228 protein /FL=gb:BC001224.1 BC001224 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 211379_x_at AB050855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB050855.1 /DEF=Homo sapiens beta3GalNAcT-1 mRNA for globoside synthase, complete cds, clone:type 1. /FEA=mRNA /GEN=beta3GalNAcT-1 /PROD=globoside synthase /DB_XREF=gi:11136454 /UG=Hs.267695 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 /FL=gb:AB050855.1 AB050855 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) B3GALNT1 8706 NM_001038628 /// NM_003781 /// NM_033167 /// NM_033168 /// NM_033169 /// XM_005247859 /// XM_005247861 /// XM_005247862 /// XM_005247864 /// XM_006713802 /// XM_006713803 /// XM_006713804 /// XM_006713805 /// XM_006713806 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047273 // galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity // inferred from electronic annotation 211380_s_at D45864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D45864.1 /DEF=Homo sapiens mRNA for cGMP-dependent protein kinase type I alpha, complete cds. /FEA=mRNA /PROD=cGMP-dependent protein kinase type I alpha /DB_XREF=gi:1255601 /UG=Hs.2689 protein kinase, cGMP-dependent, type I /FL=gb:D45864.1 D45864 protein kinase, cGMP-dependent, type I PRKG1 5592 NM_001098512 /// NM_006258 /// XM_005269970 /// XM_005269971 /// XM_005269972 0001764 // neuron migration // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0090331 // negative regulation of platelet aggregation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004692 // cGMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from electronic annotation 211381_x_at AF168617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF168617.1 /DEF=Homo sapiens HE2 beta1 mRNA, complete cds. /FEA=mRNA /PROD=HE2 beta1 /DB_XREF=gi:7140925 /UG=Hs.2717 sperm associated antigen 11 /FL=gb:AF168617.1 AF168617 sperm associated antigen 11A /// sperm associated antigen 11B SPAG11A /// SPAG11B 10407 /// 653423 NM_001081552 /// NM_016512 /// NM_058200 /// NM_058201 /// NM_058202 /// NM_058203 /// NM_058206 /// NM_058207 /// XM_005272391 /// XM_005272392 /// XM_005272393 0006952 // defense response // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation 211382_s_at AF220152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220152.2 /DEF=Homo sapiens TACC2 mRNA, complete cds. /FEA=mRNA /PROD=TACC2 /DB_XREF=gi:7934571 /UG=Hs.272023 transforming, acidic coiled-coil containing protein 2 /FL=gb:AF220152.2 AF220152 transforming, acidic coiled-coil containing protein 2 TACC2 10579 NM_001291876 /// NM_001291877 /// NM_001291878 /// NM_001291879 /// NM_006997 /// NM_206860 /// NM_206861 /// NM_206862 /// XM_005269388 /// XM_005269389 /// XM_005269390 /// XM_005269391 /// XM_005269392 /// XM_005269393 /// XM_005269394 /// XM_005269395 /// XM_005269396 /// XM_005269397 /// XM_005269399 /// XM_006717548 /// XM_006717549 /// XM_006717550 /// XM_006717551 /// XM_006717552 /// XM_006717553 /// XM_006717554 /// XM_006717555 /// XM_006717556 /// XM_006717557 /// XM_006717558 /// XM_006717559 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030953 // astral microtubule organization // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay 211383_s_at AL136827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136827.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F2427 (from clone DKFZp434F2427); complete cds. /FEA=mRNA /GEN=DKFZp434F2427 /PROD=hypothetical protein /DB_XREF=gi:6807664 /UG=Hs.27207 KIAA0982 protein /FL=gb:AL136827.1 AL136827 WD repeat domain 37 WDR37 22884 NM_014023 0005515 // protein binding // inferred from electronic annotation 211384_s_at D50855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50855.1 /DEF=Human mRNA for Ca-sensing receptor, complete cds. /FEA=mRNA /PROD=Ca-sensing receptor /DB_XREF=gi:904209 /UG=Hs.272429 calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism) /FL=gb:NM_000388.1 gb:U20759.1 gb:D50855.1 D50855 calcium-sensing receptor CASR 846 NM_000388 /// NM_001178065 /// XM_005247836 /// XM_005247837 /// XM_006713789 /// XM_006713790 0001503 // ossification // traceable author statement /// 0002931 // response to ischemia // inferred from electronic annotation /// 0005513 // detection of calcium ion // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007635 // chemosensory behavior // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071404 // cellular response to low-density lipoprotein particle stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0019808 // polyamine binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation 211385_x_at U28169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U28169.1 /DEF=Human clone hast4v aryl sulfotransferase mRNA, complete cds. /FEA=mRNA /PROD=aryl sulfotransferase /DB_XREF=gi:881502 /UG=Hs.272462 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 /FL=gb:U28169.1 gb:U28170.1 U28169 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 SULT1A2 6799 NM_001054 /// NM_177528 /// XM_006721076 /// XM_006721077 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009309 // amine biosynthetic process // traceable author statement /// 0018958 // phenol-containing compound metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004062 // aryl sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay 211386_at BC005372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005372.1 /DEF=Homo sapiens, clone MGC:12488, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12488) /DB_XREF=gi:13529217 /UG=Hs.273427 Homo sapiens, clone MGC:12488, mRNA, complete cds /FL=gb:BC005372.1 BC005372 uncharacterized protein MGC12488 MGC12488 84786 211387_x_at AB012143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012143.1 /DEF=Homo sapiens hCAP1b mRNA for mRNA capping enzyme, complete cds. /FEA=mRNA /GEN=hCAP1b /PROD=mRNA capping enzyme /DB_XREF=gi:2979497 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AB012143.1 AB012143 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 211388_s_at U80761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U80761.1 /DEF=Homo sapiens CTG26 alternate open reading frame mRNA, complete cds. /FEA=mRNA /GEN=CTG26 /PROD=CTG26 alternate open reading frame /DB_XREF=gi:2565090 /UG=Hs.274482 CTG26 alternate open reading frame /FL=gb:U80761.1 U80761 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0072365 // regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 211389_x_at U73396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73396.1 /DEF=Human NK-receptor (KIR-123FM) mRNA, complete cds. /FEA=mRNA /GEN=KIR-123FM /PROD=NK-receptor /DB_XREF=gi:1890669 /UG=Hs.274601 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 /FL=gb:U30273.1 gb:U30274.1 gb:U73396.1 gb:AF022044.1 gb:AF022049.1 gb:AF103010.1 gb:AF103011.1 gb:AF103012.1 gb:AF103013.1 gb:NM_013289.1 gb:L41269.1 gb:U31416.1 U73396 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 KIR3DS1 3813 NM_001083539 /// NM_001282170 /// NM_001282171 /// XM_005272923 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0032393 // MHC class I receptor activity // non-traceable author statement 211390_at AF113009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113009.1 /DEF=Homo sapiens PRO0297 mRNA, complete cds. /FEA=mRNA /PROD=PRO0297 /DB_XREF=gi:6642741 /UG=Hs.277888 PRO0297 protein /FL=gb:AF113009.1 gb:NM_014081.1 AF113009 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 211391_s_at AF254087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF254087.1 /DEF=Homo sapiens EWSZSG fusion protein long A isoform (EWSZSG fusion) mRNA, complete cds. /FEA=mRNA /GEN=EWSZSG fusion /PROD=EWSZSG fusion protein long A isoform /DB_XREF=gi:9954382 /UG=Hs.27801 zinc finger protein 278 /FL=gb:AF254087.1 AF254087 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211392_s_at AF242522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF242522.1 /DEF=Homo sapiens krueppel-related zinc finger protein SBZF5 mRNA, complete cds. /FEA=mRNA /PROD=krueppel-related zinc finger protein SBZF5 /DB_XREF=gi:9802041 /UG=Hs.27801 zinc finger protein 278 /FL=gb:AF242522.1 AF242522 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211393_at AF242522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF242522.1 /DEF=Homo sapiens krueppel-related zinc finger protein SBZF5 mRNA, complete cds. /FEA=mRNA /PROD=krueppel-related zinc finger protein SBZF5 /DB_XREF=gi:9802041 /UG=Hs.27801 zinc finger protein 278 /FL=gb:AF242522.1 AF242522 POZ (BTB) and AT hook containing zinc finger 1 PATZ1 23598 NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211395_x_at U90940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90940.1 /DEF=Homo sapiens cell-type natural killer cells Fc gamma receptor IIc3 (Fc-gammaRIIC) mRNA, complete cds. /FEA=mRNA /GEN=Fc-gammaRIIC /PROD=Fc gamma receptor IIc3 /DB_XREF=gi:2149629 /UG=Hs.278443 Fc fragment of IgG, low affinity IIb, receptor for (CD32) /FL=gb:U90940.1 U90940 Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) FCGR2C 9103 NM_001005410 /// NM_001005411 /// NM_001005412 /// NM_201563 /// NR_047648 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from electronic annotation 211396_at U90941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U90941.1 /DEF=Homo sapiens cell-type natural killer cells Fc gamma receptor RIIc4 (Fc-gammaRIIC) mRNA, complete cds. /FEA=mRNA /GEN=Fc-gammaRIIC /PROD=Fc gamma receptor RIIc4 /DB_XREF=gi:2149631 /UG=Hs.278443 Fc fragment of IgG, low affinity IIb, receptor for (CD32) /FL=gb:U90941.1 U90941 Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) FCGR2C 9103 NM_001005410 /// NM_001005411 /// NM_001005412 /// NM_201563 /// NR_047648 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from electronic annotation 211397_x_at L76669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76669.1 /DEF=Homo sapiens NKAT6 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:1217724 /UG=Hs.278454 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 /FL=gb:L76669.1 gb:NM_014219.1 gb:U24075.1 L76669 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 KIR2DL2 3803 NM_014219 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211398_at AB030075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030075.1 /DEF=Homo sapiens mRNA for K-sam-IIH3, complete cds. /FEA=mRNA /GEN=K-sam /PROD=K-sam-IIH3 /DB_XREF=gi:6691448 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:AB030075.1 AB030075 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211399_at AB030077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030077.1 /DEF=Homo sapiens mRNA for K-sam-IIO2, complete cds. /FEA=mRNA /GEN=K-sam /PROD=K-sam-IIO2 /DB_XREF=gi:6691452 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:AB030077.1 AB030077 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211400_at AB030073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030073.1 /DEF=Homo sapiens mRNA for K-sam-IIH1, complete cds. /FEA=mRNA /GEN=K-sam /PROD=K-sam-IIH1 /DB_XREF=gi:6691444 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:AB030073.1 AB030073 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211401_s_at AB030078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB030078.1 /DEF=Homo sapiens mRNA for K-sam-IIO3, complete cds. /FEA=mRNA /GEN=K-sam /PROD=K-sam-IIO3 /DB_XREF=gi:6691454 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:AB030078.1 AB030078 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211402_x_at AF004291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF004291.1 /DEF=Homo sapiens germ cell nuclear factor (GCNF) mRNA, complete cds. /FEA=mRNA /GEN=GCNF /PROD=germ cell nuclear factor /DB_XREF=gi:2209118 /UG=Hs.278599 nuclear receptor subfamily 6, group A, member 1 /FL=gb:AF004291.1 AF004291 nuclear receptor subfamily 6, group A, member 1 NR6A1 2649 NM_001278546 /// NM_001489 /// NM_033334 /// NM_033335 /// XM_005251917 /// XM_005251918 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007276 // gamete generation // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211403_x_at AF167079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF167079.1 /DEF=Homo sapiens variably charged X-B (VCXB) mRNA, complete cds. /FEA=mRNA /GEN=VCXB /PROD=variably charged X-B /DB_XREF=gi:11934657 /UG=Hs.278906 variable charge, X chromosome /FL=gb:AF167079.1 AF167079 variable charge, X-linked 2 VCX2 51480 NM_016378 211404_s_at BC004371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004371.1 /DEF=Homo sapiens, clone MGC:10449, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10449) /DB_XREF=gi:13325115 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 /FL=gb:BC004371.1 BC004371 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 211405_x_at M38289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M38289.1 /DEF=Human leucocyte interferon mRNA, complete cds. /FEA=mRNA /GEN=IFNA /DB_XREF=gi:186407 /UG=Hs.282276 interferon, alpha 17 /FL=gb:NM_021268.1 gb:M11026.1 gb:M38289.1 M38289 interferon, alpha 17 IFNA17 3451 NM_021268 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005132 // type I interferon receptor binding // not recorded 211406_at AF119875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119875.1 /DEF=Homo sapiens PRO2309 mRNA, complete cds. /FEA=mRNA /PROD=PRO2309 /DB_XREF=gi:7770186 /UG=Hs.283037 HSPC039 protein /FL=gb:AF119875.1 AF119875 immediate early response 3 interacting protein 1 IER3IP1 51124 NM_016097 2000269 // regulation of fibroblast apoptotic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211407_at M33374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33374.1 /DEF=Human cell adhesion protein (SQM1) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:180232 /UG=Hs.283748 Human cell adhesion protein (SQM1) mRNA, complete cds /FL=gb:M33374.1 M33374 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa NDUFB7 4713 NM_004146 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 211410_x_at AF217487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF217487.1 /DEF=Homo sapiens killer cell Ig-like receptor KIR2DL5.3 (KIR2DL5.3) mRNA, complete cds. /FEA=mRNA /GEN=KIR2DL5.3 /PROD=killer cell Ig-like receptor KIR2DL5.3 /DB_XREF=gi:11528059 /UG=Hs.283815 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5 /FL=gb:AF217487.1 gb:NM_020535.1 gb:AF271607.1 gb:AF271608.1 gb:AF204903.1 AF217487 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A KIR2DL5A 57292 NM_020535 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211411_at AF117899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF117899.1 /DEF=Homo sapiens LDLR-FUT fusion protein (LDLR-FUT) mRNA, complete cds. /FEA=mRNA /GEN=LDLR-FUT /PROD=LDLR-FUT fusion protein /DB_XREF=gi:6739499 /UG=Hs.283926 Homo sapiens LDLR-FUT fusion protein (LDLR-FUT) mRNA, complete cds /FL=gb:AF117899.1 AF117899 211412_at AF229067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229067.1 /DEF=Homo sapiens PADI-H protein mRNA, complete cds. /FEA=mRNA /PROD=PADI-H protein /DB_XREF=gi:8980666 /UG=Hs.283960 Homo sapiens PADI-H protein mRNA, complete cds /FL=gb:AF229067.1 AF229067 peptidyl arginine deiminase, type IV PADI4 23569 NM_012387 0002376 // immune system process // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0016568 // chromatin modification // inferred from sequence or structural similarity /// 0018101 // protein citrullination // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0036413 // histone H3-R26 citrullination // inferred from direct assay /// 0036414 // histone citrullination // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004668 // protein-arginine deiminase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016990 // arginine deiminase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211413_s_at AF229067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229067.1 /DEF=Homo sapiens PADI-H protein mRNA, complete cds. /FEA=mRNA /PROD=PADI-H protein /DB_XREF=gi:8980666 /UG=Hs.283960 Homo sapiens PADI-H protein mRNA, complete cds /FL=gb:AF229067.1 AF229067 peptidyl arginine deiminase, type IV PADI4 23569 NM_012387 0002376 // immune system process // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0016568 // chromatin modification // inferred from sequence or structural similarity /// 0018101 // protein citrullination // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0036413 // histone H3-R26 citrullination // inferred from direct assay /// 0036414 // histone citrullination // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004668 // protein-arginine deiminase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016990 // arginine deiminase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211414_at AF097495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF097495.1 /DEF=Homo sapiens glutaminase isoform M precursor, mRNA, complete cds. /FEA=mRNA /PROD=glutaminase isoform M precursor /DB_XREF=gi:6002675 /UG=Hs.284195 Homo sapiens glutaminase isoform M precursor, mRNA, complete cds /FL=gb:AF097495.1 AF097495 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 211416_x_at L20492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20492.1 /DEF=Human gamma-glutamyl transpeptidase mRNA, complete cds. /FEA=mRNA /PROD=gamma-glutamyl transpeptidase /DB_XREF=gi:306752 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:L20492.1 L20492 gamma-glutamyltransferase light chain 1 GGTLC1 92086 NM_080920 /// NM_178311 /// NM_178312 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_006723661 /// XM_006723662 0006749 // glutathione metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity 0031362 // anchored component of external side of plasma membrane // traceable author statement 0003840 // gamma-glutamyltransferase activity // traceable author statement 211417_x_at L20493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20493.1 /DEF=Human gamma-glutamyl transpeptidase mRNA, complete cds. /FEA=mRNA /PROD=gamma-glutamyl transpeptidase /DB_XREF=gi:306754 /UG=Hs.284380 gamma-glutamyltransferase 1 /FL=gb:L20493.1 L20493 gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 2 /// gamma-glutamyltransferase light chain 1 /// gamma-glutamyltransferase light chain 2 GGT1 /// GGT2 /// GGTLC1 /// GGTLC2 2678 /// 91227 /// 92086 /// 728441 NM_001032364 /// NM_001032365 /// NM_001282879 /// NM_001288833 /// NM_005265 /// NM_013421 /// NM_013430 /// NM_080839 /// NM_080920 /// NM_178311 /// NM_178312 /// NM_199127 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_005261888 /// XM_005261890 /// XM_006723661 /// XM_006723662 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 /// XM_006724392 /// XM_006724393 /// XM_006724394 /// XM_006724395 /// XM_006724396 /// XM_006724397 /// XM_006726820 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from mutant phenotype /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // inferred from direct assay /// 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay 211419_s_at L29126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L29126.1 /DEF=Homo sapiens beta2-chimaerin mRNA, complete cds. /FEA=mRNA /PROD=beta2-chimaerin /DB_XREF=gi:457229 /UG=Hs.286055 chimerin (chimaerin) 2 /FL=gb:L29126.1 gb:U07223.1 L29126 chimerin 2 CHN2 1124 NM_001039936 /// NM_001293069 /// NM_001293070 /// NM_001293071 /// NM_001293072 /// NM_001293073 /// NM_001293075 /// NM_001293076 /// NM_001293077 /// NM_001293078 /// NM_001293079 /// NM_001293080 /// NM_001293081 /// NM_004067 /// NR_120524 /// NR_120525 /// XM_005249599 /// XM_005249602 /// XR_171041 /// XR_171649 /// XR_172478 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211421_s_at M31213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31213.1 /DEF=Human papillary thyroid carcinoma-encoded protein mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:190699 /UG=Hs.287270 ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease) /FL=gb:M31213.1 M31213 ret proto-oncogene RET 5979 NM_000323 /// NM_020629 /// NM_020630 /// NM_020975 /// XM_006717936 0000165 // MAPK cascade // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 211422_at AL136545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136545.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761A19121 (from clone DKFZp761A19121); complete cds. /FEA=mRNA /GEN=DKFZp761A19121 /PROD=hypothetical protein /DB_XREF=gi:12052727 /UG=Hs.287445 hypothetical protein FLJ11726 /FL=gb:AL136545.1 AL136545 transient receptor potential cation channel, subfamily M, member 3 TRPM3 80036 NM_001007470 /// NM_001007471 /// NM_020952 /// NM_024971 /// NM_206944 /// NM_206945 /// NM_206946 /// NM_206947 /// NM_206948 /// XM_005252218 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation 211423_s_at D85181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D85181.1 /DEF=Homo sapiens mRNA for fungal sterol-C5-desaturase homolog, complete cds. /FEA=mRNA /PROD=fungal sterol-C5-desaturase homolog /DB_XREF=gi:1906795 /UG=Hs.288031 sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like /FL=gb:D85181.1 D85181 sterol-C5-desaturase SC5D 6309 NM_001024956 /// NM_006918 0006629 // lipid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033490 // cholesterol biosynthetic process via lathosterol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000248 // C-5 sterol desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050046 // lathosterol oxidase activity // inferred from electronic annotation 211424_x_at AF113007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF113007.1 /DEF=Homo sapiens PRO0066 mRNA, complete cds. /FEA=mRNA /PROD=PRO0066 /DB_XREF=gi:6642737 /UG=Hs.288771 DKFZP586A0522 protein /FL=gb:AF113007.1 AF113007 methyltransferase like 7A METTL7A 25840 NM_014033 /// XM_006719332 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 211425_x_at AF257500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF257500.1 /DEF=Homo sapiens SYTSSX4 fusion protein (SSXTSSX4 fusion) mRNA, complete cds. /FEA=mRNA /GEN=SSXTSSX4 fusion /PROD=SYTSSX4 fusion protein /DB_XREF=gi:11127694 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 /FL=gb:AF257500.1 gb:AF230662.1 AF257500 synovial sarcoma, X breakpoint 4 /// synovial sarcoma, X breakpoint 4B SSX4 /// SSX4B 6759 /// 548313 NM_001034832 /// NM_001040612 /// NM_005636 /// NM_175729 /// XM_006726844 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 211426_x_at U40038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U40038.1 /DEF=Human GTP-binding protein alpha q subunit (GNAQ) mRNA, complete cds. /FEA=mRNA /GEN=GNAQ /PROD=GTP-binding protein alpha q subunit /DB_XREF=gi:1181670 /UG=Hs.296261 guanine nucleotide binding protein (G protein), q polypeptide /FL=gb:U40038.1 U40038 guanine nucleotide binding protein (G protein), q polypeptide GNAQ 2776 NM_002072 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007215 // glutamate receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016322 // neuron remodeling // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 211427_s_at AB013889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013889.1 /DEF=Homo sapiens mRNA for inward rectifier potassium channel Kir7.1, complete cds. /FEA=mRNA /PROD=inward rectifier potassium channel Kir7.1 /DB_XREF=gi:3138788 /UG=Hs.296361 potassium inwardly-rectifying channel,subfamily J, member 13 /FL=gb:AB013889.1 AB013889 potassium inwardly-rectifying channel, subfamily J, member 13 KCNJ13 3769 NM_001172416 /// NM_001172417 /// NM_002242 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // non-traceable author statement 0008076 // voltage-gated potassium channel complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // non-traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 211428_at AF119873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119873.1 /DEF=Homo sapiens PRO2275 mRNA, complete cds. /FEA=mRNA /PROD=PRO2275 /DB_XREF=gi:7770182 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 /FL=gb:AF119873.1 AF119873 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 SERPINA1 5265 NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211429_s_at AF119873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119873.1 /DEF=Homo sapiens PRO2275 mRNA, complete cds. /FEA=mRNA /PROD=PRO2275 /DB_XREF=gi:7770182 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 /FL=gb:AF119873.1 AF119873 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 SERPINA1 5265 NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211430_s_at M87789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M87789.1 /DEF=Human (hybridoma H210) anti-hepatitis A IgG variable region, constant region, complementarity-determining regions mRNA, complete cds. /FEA=mRNA /PROD=IgG /DB_XREF=gi:185361 /UG=Hs.300697 immunoglobulin heavy constant gamma 3 (G3m marker) /FL=gb:M87789.1 M87789 immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 /// microRNA 8071-1 /// microRNA 8071-2 IGHG1 /// IGHG2 /// IGHM /// IGHV4-31 /// MIR8071-1 /// MIR8071-2 3500 /// 3501 /// 3507 /// 28396 /// 102465871 /// 102466889 NR_107038 /// NR_107059 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211431_s_at D50479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D50479.1 /DEF=Homo sapiens mRNA for protein-tyrosine kinase, complete cds. /FEA=mRNA /GEN=byk /PROD=protein-tyrosine kinase /DB_XREF=gi:2329844 /UG=Hs.301 TYRO3 protein tyrosine kinase /FL=gb:D50479.1 gb:U05682.1 gb:D17517.1 D50479 TYRO3 protein tyrosine kinase TYRO3 7301 NM_006293 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0021885 // forebrain cell migration // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // non-traceable author statement /// 0030168 // platelet activation // inferred from sequence or structural similarity /// 0032940 // secretion by cell // inferred from sequence or structural similarity /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042698 // ovulation cycle // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070050 // neuron cellular homeostasis // inferred from sequence or structural similarity /// 0070527 // platelet aggregation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211432_s_at U05682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U05682.1 /DEF=Human receptor-type tyrosine kinase (rse) mRNA, complete cds. /FEA=mRNA /GEN=rse /PROD=Rse /DB_XREF=gi:463469 /UG=Hs.301 TYRO3 protein tyrosine kinase /FL=gb:D50479.1 gb:U05682.1 gb:D17517.1 U05682 TYRO3 protein tyrosine kinase TYRO3 7301 NM_006293 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0021885 // forebrain cell migration // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // non-traceable author statement /// 0030168 // platelet activation // inferred from sequence or structural similarity /// 0032940 // secretion by cell // inferred from sequence or structural similarity /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042698 // ovulation cycle // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070050 // neuron cellular homeostasis // inferred from sequence or structural similarity /// 0070527 // platelet aggregation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211433_x_at AL583909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL583909.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761J197 (from clone DKFZp761J197); complete cds. /FEA=mRNA /GEN=DKFZp761J197 /PROD=hypothetical protein /DB_XREF=gi:13093772 /UG=Hs.301696 hypothetical protein FLJ11560 /FL=gb:AL583909.1 AL583909 family with sequence similarity 214, member B FAM214B 80256 NM_025182 /// XM_005251588 /// XM_005251589 /// XM_005251590 /// XM_005251591 /// XM_005251592 /// XM_005251593 /// XM_005251594 /// XM_005251595 /// XM_005251596 /// XM_005251597 /// XM_005251598 /// XM_006716877 /// XM_006716878 0005634 // nucleus // inferred from direct assay 211434_s_at AF015524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015524.1 /DEF=Homo sapiens putative chemokine receptor (CRAM-A) mRNA, complete cds. /FEA=mRNA /GEN=CRAM-A /PROD=putative chemokine receptor /DB_XREF=gi:3550066 /UG=Hs.302043 chemokine (C-C motif) receptor-like 2 /FL=gb:AF015524.1 AF015524 chemokine (C-C motif) receptor-like 2 CCRL2 9034 NM_001130910 /// NM_003965 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from physical interaction /// 0048020 // CCR chemokine receptor binding // inferred from physical interaction 211435_at AF202635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF202635.1 /DEF=Homo sapiens PP1200 mRNA, complete cds. /FEA=mRNA /PROD=PP1200 /DB_XREF=gi:10732645 /UG=Hs.302135 Homo sapiens PP1200 mRNA, complete cds /FL=gb:AF202635.1 AF202635 211436_at AF130053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130053.1 /DEF=Homo sapiens clone FLB4228 PRO1095 mRNA, complete cds. /FEA=mRNA /PROD=PRO1095 /DB_XREF=gi:11493412 /UG=Hs.302145 Homo sapiens clone FLB4228 PRO1095 mRNA, complete cds /FL=gb:AF130053.1 AF130053 211437_at AF130093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130093.1 /DEF=Homo sapiens clone FLB9835 PRO2660 mRNA, complete cds. /FEA=mRNA /PROD=PRO2660 /DB_XREF=gi:11493490 /UG=Hs.302153 Homo sapiens clone FLB9835 PRO2660 mRNA, complete cds /FL=gb:AF130093.1 AF130093 211438_at D16845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D16845.1 /DEF=Human mRNA for thyrotropin-releasing hormone receptor, complete cds. /FEA=mRNA /PROD=human thyrotropin-releasing hormone receptor /DB_XREF=gi:577631 /UG=Hs.3022 thyrotropin-releasing hormone receptor /FL=gb:NM_003301.1 gb:D16845.1 D16845 thyrotropin-releasing hormone receptor TRHR 7201 NM_003301 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004997 // thyrotropin-releasing hormone receptor activity // inferred from electronic annotation 211439_at AF055270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF055270.1 /DEF=Homo sapiens heat-shock suppressed protein 1 (HSSG1) mRNA, complete cds. /FEA=mRNA /GEN=HSSG1 /PROD=heat-shock suppressed protein 1 /DB_XREF=gi:6002475 /UG=Hs.306194 heat-shock suppressed protein 1 /FL=gb:AF055270.1 AF055270 serine/arginine-rich splicing factor 7 SRSF7 6432 NM_001031684 /// NM_001195446 /// NM_006276 /// XM_005264484 /// XM_005264485 /// XM_005264486 /// XR_426994 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211440_x_at AF280110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280110.1 /DEF=Homo sapiens clone 15b cytochrome P450 subfamily IIIA polypeptide 43 (CYP3A43) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=CYP3A43 /PROD=cytochrome P450 subfamily IIIA polypeptide 43 /DB_XREF=gi:11225241 /UG=Hs.306220 cytochrome P450 polypeptide 43 /FL=gb:AF280110.1 AF280110 cytochrome P450, family 3, subfamily A, polypeptide 43 CYP3A43 64816 NM_001278921 /// NM_022820 /// NM_057095 /// NM_057096 /// NR_103868 /// NR_103869 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 211441_x_at AF280113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280113.1 /DEF=Homo sapiens clone 15g cytochrome P450 subfamily IIIA polypeptide 43 (CYP3A43) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=CYP3A43 /PROD=cytochrome P450 subfamily IIIA polypeptide 43 /DB_XREF=gi:11225247 /UG=Hs.306220 cytochrome P450 polypeptide 43 /FL=gb:AF280113.1 AF280113 cytochrome P450, family 3, subfamily A, polypeptide 43 CYP3A43 64816 NM_001278921 /// NM_022820 /// NM_057095 /// NM_057096 /// NR_103868 /// NR_103869 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 211442_x_at AF280111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF280111.1 /DEF=Homo sapiens clone 15d cytochrome P450 subfamily IIIA polypeptide 43 (CYP3A43) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=CYP3A43 /PROD=cytochrome P450 subfamily IIIA polypeptide 43 /DB_XREF=gi:11225243 /UG=Hs.306220 cytochrome P450 polypeptide 43 /FL=gb:AF280111.1 AF280111 cytochrome P450, family 3, subfamily A, polypeptide 43 CYP3A43 64816 NM_001278921 /// NM_022820 /// NM_057095 /// NM_057096 /// NR_103868 /// NR_103869 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 211444_at BC002811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002811.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20378, clone MGC:3513, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20378 /DB_XREF=gi:12803928 /UG=Hs.306988 Homo sapiens, Similar to hypothetical protein FLJ20378, clone MGC:3513, mRNA, complete cds /FL=gb:BC002811.1 BC002811 RP11-649A18.7 211445_x_at AF315951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF315951.1 /DEF=Homo sapiens FKSG17 (FKSG17) mRNA, complete cds. /FEA=mRNA /GEN=FKSG17 /PROD=FKSG17 /DB_XREF=gi:12276119 /UG=Hs.307057 Homo sapiens FKSG17 (FKSG17) mRNA, complete cds /FL=gb:AF315951.1 AF315951 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 NACAP1 83955 NM_032031 /// NR_002182 211446_at AL136902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136902.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E169 (from clone DKFZp434E169); complete cds. /FEA=mRNA /GEN=DKFZp434E169 /PROD=hypothetical protein /DB_XREF=gi:12053300 /UG=Hs.307080 Homo sapiens mRNA; cDNA DKFZp434E169 (from clone DKFZp434E169); complete cds /FL=gb:AL136902.1 AL136902 regulator of G-protein signaling like 1 RGSL1 353299 NM_001137669 /// NM_032267 /// NM_181572 /// XM_005245137 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211447_s_at U18088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18088.1 /DEF=Human 3,5-cyclic AMP phosphodiesterase inactive splice variant HSPDE4A7A mRNA, complete cds. /FEA=mRNA /PROD=3,5-cyclic AMP phosphodiesterase HSPDE4A7A /DB_XREF=gi:604376 /UG=Hs.307164 Human 3,5-cyclic AMP phosphodiesterase inactive splice variant HSPDE4A7A mRNA, complete cds /FL=gb:U18088.1 U18088 phosphodiesterase 4A, cAMP-specific PDE4A 5141 NM_001111307 /// NM_001111308 /// NM_001111309 /// NM_001243121 /// NM_006202 /// XM_005259933 /// XM_006722765 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211448_s_at AF107619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF107619.1 /DEF=Homo sapiens regulator of G-protein signaling-6 (RGS6) mRNA, complete cds. /FEA=mRNA /GEN=RGS6 /PROD=regulator of G-protein signaling-6 /DB_XREF=gi:4972616 /UG=Hs.3221 regulator of G-protein signalling 6 /FL=gb:AF107619.1 AF107619 regulator of G-protein signaling 6 RGS6 9628 NM_001204416 /// NM_001204417 /// NM_001204418 /// NM_001204419 /// NM_001204420 /// NM_001204421 /// NM_001204422 /// NM_001204423 /// NM_001204424 /// NM_004296 /// XM_005268234 /// XM_005268235 /// XM_005268236 /// XM_006720327 /// XM_006720328 /// XM_006720329 /// XM_006720330 /// XM_006720331 /// XM_006720332 /// XM_006720333 /// XR_429335 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 211449_at D89646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89646.1 /DEF=Homo sapiens GTBP mRNA for GTBP-ALT, complete cds. /FEA=mRNA /GEN=GTBP /PROD=GTBP-ALT /DB_XREF=gi:2687868 /UG=Hs.3248 mutS (E. coli) homolog 6 /FL=gb:D89646.1 D89646 mutS homolog 6 MSH6 2956 NM_000179 /// NM_001281492 /// NM_001281493 /// NM_001281494 /// XM_005264271 0000710 // meiotic mismatch repair // not recorded /// 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from sequence or structural similarity /// 0009411 // response to UV // not recorded /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000228 // nuclear chromosome // not recorded /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 211450_s_at D89646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D89646.1 /DEF=Homo sapiens GTBP mRNA for GTBP-ALT, complete cds. /FEA=mRNA /GEN=GTBP /PROD=GTBP-ALT /DB_XREF=gi:2687868 /UG=Hs.3248 mutS (E. coli) homolog 6 /FL=gb:D89646.1 D89646 mutS homolog 6 MSH6 2956 NM_000179 /// NM_001281492 /// NM_001281493 /// NM_001281494 /// XM_005264271 0000710 // meiotic mismatch repair // not recorded /// 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from sequence or structural similarity /// 0009411 // response to UV // not recorded /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000228 // nuclear chromosome // not recorded /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 211451_s_at U24056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24056.1 /DEF=Human inward rectifier K+ channel protein (hirk2) mRNA, complete cds. /FEA=mRNA /GEN=hirk2 /PROD=inward rectifier K+ channel protein /DB_XREF=gi:775226 /UG=Hs.32505 potassium inwardly-rectifying channel, subfamily J, member 4 /FL=gb:U24056.1 U24056 potassium inwardly-rectifying channel, subfamily J, member 4 KCNJ4 3761 NM_004981 /// NM_152868 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 211452_x_at AF130054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130054.1 /DEF=Homo sapiens clone FLB4816 PRO1252 mRNA, complete cds. /FEA=mRNA /PROD=PRO1252 /DB_XREF=gi:11493414 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:AF130054.1 AF130054 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 211453_s_at M77198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M77198.1 /DEF=Human rac protein kinase beta mRNA, complete cds. /FEA=mRNA /PROD=rac protein kinase-beta /DB_XREF=gi:337490 /UG=Hs.326445 v-akt murine thymoma viral oncogene homolog 2 /FL=gb:M77198.1 M77198 v-akt murine thymoma viral oncogene homolog 2 AKT2 208 NM_001243027 /// NM_001243028 /// NM_001626 /// XM_006723081 /// XM_006723082 /// XM_006723083 /// XM_006723084 /// XM_006723085 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0031340 // positive regulation of vesicle fusion // inferred from sequence or structural similarity /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0045444 // fat cell differentiation // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0065002 // intracellular protein transmembrane transport // inferred from sequence or structural similarity /// 0071156 // regulation of cell cycle arrest // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211454_x_at AF336878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF336878.1 /DEF=Homo sapiens FKSG51 (FKSG51) mRNA, complete cds. /FEA=mRNA /GEN=FKSG51 /PROD=FKSG51 /DB_XREF=gi:13384184 /UG=Hs.326752 Homo sapiens FKSG51 (FKSG51) mRNA, complete cds /FL=gb:AF336878.1 AF336878 FKSG49 FKSG49 400949 XR_041698 211455_at AF354444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF354444.1 /DEF=Homo sapiens IFP38 (IFP38) mRNA, complete cds. /FEA=mRNA /GEN=IFP38 /PROD=IFP38 /DB_XREF=gi:13310840 /UG=Hs.326773 Homo sapiens IFP38 (IFP38) mRNA, complete cds /FL=gb:AF354444.1 AF354444 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred from electronic annotation 211456_x_at AF333388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF333388.1 /DEF=Homo sapiens metallothionein 1H-like protein mRNA, complete cds. /FEA=mRNA /PROD=metallothionein 1H-like protein /DB_XREF=gi:13310411 /UG=Hs.326774 Homo sapiens metallothionein 1H-like protein mRNA, complete cds /FL=gb:AF333388.1 AF333388 metallothionein 1H-like 1 MT1HL1 645745 NM_001039954 /// NM_001276687 0046872 // metal ion binding // inferred from electronic annotation 211457_at AF180519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180519.1 /DEF=Homo sapiens GABA-A receptor-associated protein mRNA, complete cds. /FEA=mRNA /PROD=GABA-A receptor-associated protein /DB_XREF=gi:13241283 /UG=Hs.326776 Homo sapiens GABA-A receptor-associated protein mRNA, complete cds /FL=gb:AF180519.1 AF180519 GABA(A) receptors associated protein like 3, pseudogene GABARAPL3 23766 NR_028287 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0012501 // programmed cell death // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0050811 // GABA receptor binding // not recorded 211458_s_at AF180519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180519.1 /DEF=Homo sapiens GABA-A receptor-associated protein mRNA, complete cds. /FEA=mRNA /PROD=GABA-A receptor-associated protein /DB_XREF=gi:13241283 /UG=Hs.326776 Homo sapiens GABA-A receptor-associated protein mRNA, complete cds /FL=gb:AF180519.1 AF180519 GABA(A) receptor-associated protein like 1 /// GABA(A) receptors associated protein like 3, pseudogene GABARAPL1 /// GABARAPL3 23710 /// 23766 NM_031412 /// NR_028287 /// XM_005253344 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0012501 // programmed cell death // not recorded /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity /// 0050811 // GABA receptor binding // not recorded /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 211459_at AF234262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF234262.1 /DEF=Homo sapiens IL-1beta-regulated neutrophil survival protein mRNA, complete cds. /FEA=mRNA /PROD=IL-1beta-regulated neutrophil survival protein /DB_XREF=gi:13182974 /UG=Hs.326778 Homo sapiens IL-1beta-regulated neutrophil survival protein mRNA, complete cds /FL=gb:AF234262.1 AF234262 211460_at AF332238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332238.1 /DEF=Homo sapiens testis transcript Y 9 (TTY9) mRNA, complete cds. /FEA=mRNA /GEN=TTY9 /PROD=transcript Y 9 /DB_XREF=gi:13161119 /UG=Hs.326783 Homo sapiens testis transcript Y 9 (TTY9) mRNA, complete cds /FL=gb:AF332238.1 AF332238 testis-specific transcript, Y-linked 9A (non-protein coding) /// testis-specific transcript, Y-linked 9B (non-protein coding) TTTY9A /// TTTY9B 83864 /// 425057 NR_001530 /// NR_002159 211461_at AF332228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332228.1 /DEF=Homo sapiens melanoma-associated chondroitin sulfate proteoglycan-like mRNA, complete cds. /FEA=mRNA /PROD=melanoma-associated chondroitin sulfateproteoglycan-like /DB_XREF=gi:13161092 /UG=Hs.326786 Homo sapiens melanoma-associated chondroitin sulfate proteoglycan-like mRNA, complete cds /FL=gb:AF332228.1 AF332228 chondroitin sulfate proteoglycan 4 pseudogene 1, Y-linked CSPG4P1Y 114758 NR_001554 211462_s_at AF332222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332222.1 /DEF=Homo sapiens transducin beta-like 1 (TBL1) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=TBL1 /PROD=transducin beta-like 1 /DB_XREF=gi:13161074 /UG=Hs.326787 Homo sapiens transducin beta-like 1 (TBL1) mRNA, complete cds, alternatively spliced /FL=gb:AF332222.1 AF332222 transducin (beta)-like 1, Y-linked TBL1Y 90665 NM_033284 /// NM_134258 /// NM_134259 /// XM_005262572 /// XM_005262573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 211463_at AF332509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332509.1 /DEF=Homo sapiens zinc family member 4 protein HZIC4 (ZIC4) mRNA, complete cds. /FEA=mRNA /GEN=ZIC4 /PROD=zinc family member 4 protein HZIC4 /DB_XREF=gi:12744914 /UG=Hs.326796 Homo sapiens zinc family member 4 protein HZIC4 (ZIC4) mRNA, complete cds /FL=gb:AF332509.1 AF332509 Zic family member 4 ZIC4 84107 NM_001168378 /// NM_001168379 /// NM_001243256 /// NM_032153 /// NR_033118 /// NR_033119 /// NR_040762 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211464_x_at U20537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20537.1 /DEF=Human cysteine protease Mch2 isoform beta (Mch2) mRNA, complete cds. /FEA=mRNA /GEN=Mch2 /PROD=cysteine protease Mch2 isoform beta /DB_XREF=gi:882255 /UG=Hs.3280 caspase 6, apoptosis-related cysteine protease /FL=gb:U20537.1 U20537 caspase 6, apoptosis-related cysteine peptidase CASP6 839 NM_001226 /// NM_032992 /// XM_005263271 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004197 // cysteine-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211465_x_at U27335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27335.1 /DEF=Human alpha (1,3) fucosyltransferase (FUT6) mRNA, minor transcript I, complete cds. /FEA=mRNA /GEN=FUT6 /PROD=alpha (1,3) fucosyltransferase /DB_XREF=gi:967206 /UG=Hs.32956 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) /FL=gb:U27335.1 U27335 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) FUT6 2528 NM_000150 /// NM_001040701 /// XM_005259526 /// XM_005259527 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 211466_at U70862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U70862.1 /DEF=Human nuclear factor I B3 mRNA, complete cds. /FEA=mRNA /PROD=nuclear factor I B3 /DB_XREF=gi:1916623 /UG=Hs.33287 nuclear factor IB /FL=gb:U70862.1 U70862 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 211467_s_at U70862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U70862.1 /DEF=Human nuclear factor I B3 mRNA, complete cds. /FEA=mRNA /PROD=nuclear factor I B3 /DB_XREF=gi:1916623 /UG=Hs.33287 nuclear factor IB /FL=gb:U70862.1 U70862 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 211468_s_at AB042825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042825.1 /DEF=Homo sapiens RECQL5 gamma mRNA for DNA helicase recQ5 gamma, complete cds. /FEA=mRNA /GEN=RECQL5 gamma /PROD=DNA helicase recQ5 gamma /DB_XREF=gi:7959114 /UG=Hs.33818 RecQ protein-like 5 /FL=gb:AB042825.1 AB042825 RecQ protein-like 5 RECQL5 9400 NM_001003715 /// NM_001003716 /// NM_004259 /// XM_005257818 /// XM_005257822 /// XM_005257823 /// XM_006722186 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // non-traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // non-traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051304 // chromosome separation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211469_s_at U73531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U73531.1 /DEF=Human G protein-coupled receptor STRL33.3 (STRL33) mRNA, complete cds. /FEA=mRNA /GEN=STRL33 /PROD=G protein-coupled receptor STRL33.3 /DB_XREF=gi:2209287 /UG=Hs.34526 G protein-coupled receptor /FL=gb:U73531.1 U73531 chemokine (C-X-C motif) receptor 6 CXCR6 10663 NM_006564 /// XM_005264809 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation 211470_s_at AF186255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF186255.1 /DEF=Homo sapiens sulfotransferase 1C1 (SULT1C1) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=SULT1C1 /PROD=sulfotransferase 1C1 /DB_XREF=gi:8117858 /UG=Hs.38084 sulfotransferase family, cytosolic, 1C, member 1 /FL=gb:AF186254.1 gb:AF186255.1 gb:AF186256.1 AF186255 sulfotransferase family, cytosolic, 1C, member 2 SULT1C2 6819 NM_001056 /// NM_176825 /// XM_005264013 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009308 // amine metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008146 // sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 211471_s_at AF133588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF133588.1 /DEF=Homo sapiens RAB36 (RAB36) mRNA, complete cds. /FEA=mRNA /GEN=RAB36 /PROD=RAB36 /DB_XREF=gi:6049163 /UG=Hs.38772 RAB36, member RAS oncogene family /FL=gb:AF133588.1 AF133588 RAB36, member RAS oncogene family RAB36 9609 NM_004914 /// XM_005261859 /// XM_006724381 /// XM_006724382 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 211472_at AF336795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF336795.1 /DEF=Homo sapiens NM-4 mRNA, complete cds. /FEA=mRNA /PROD=NM-4 /DB_XREF=gi:13384166 /UG=Hs.3989 plexin B2 /FL=gb:AF336795.1 AF336795 plexin B2 PLXNB2 23654 NM_012401 /// XM_005261908 /// XM_005261909 /// XM_005261910 /// XM_005261911 /// XM_006724413 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity /// 2001222 // regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity 211473_s_at U04845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U04845.1 /DEF=Human a6(IV) collagen (COL4A6) mRNA, complete cds. /FEA=mRNA /GEN=COL4A6 /PROD=A type IV collagen /DB_XREF=gi:496977 /UG=Hs.408 collagen, type IV, alpha 6 /FL=gb:U04845.1 U04845 collagen, type IV, alpha 6 COL4A6 1288 NM_001287758 /// NM_001287759 /// NM_001287760 /// NM_001847 /// NM_033641 /// XM_006724617 /// XM_006724618 0007155 // cell adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005198 // structural molecule activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation 211474_s_at BC004948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004948.1 /DEF=Homo sapiens, clone MGC:10846, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10846) /DB_XREF=gi:13436313 /UG=Hs.41072 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6 /FL=gb:BC004948.1 BC004948 serpin peptidase inhibitor, clade B (ovalbumin), member 6 SERPINB6 5269 NM_001195291 /// NM_001271822 /// NM_001271823 /// NM_001271824 /// NM_001271825 /// NM_004568 /// XM_005249181 /// XM_005249183 /// XM_006715112 /// XM_006715113 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0030162 // regulation of proteolysis // not recorded 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 211475_s_at AF116273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116273.1 /DEF=Homo sapiens Bag1 protein variant mRNA, complete cds. /FEA=mRNA /PROD=Bag1 protein variant /DB_XREF=gi:4583370 /UG=Hs.41714 BCL2-associated athanogene /FL=gb:AF116273.1 AF116273 BCL2-associated athanogene BAG1 573 NM_001172415 /// NM_004323 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 211476_at AY013295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY013295.1 /DEF=Homo sapiens calcineurin-binding protein calsarcin-1 mRNA, complete cds. /FEA=mRNA /PROD=calcineurin-binding protein calsarcin-1 /DB_XREF=gi:11693027 /UG=Hs.42346 calcineurin-binding protein calsarcin-1 /FL=gb:AY013295.1 gb:BC005195.1 AY013295 myozenin 2 MYOZ2 51778 NM_016599 /// XM_006714234 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // non-traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030346 // protein phosphatase 2B binding // non-traceable author statement /// 0031433 // telethonin binding // inferred from physical interaction 211478_s_at M74777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M74777.1 /DEF=Human dipeptidyl peptidase IV (CD26) mRNA, complete cds. /FEA=mRNA /GEN=CD26 /PROD=dipeptidyl peptidase IV /DB_XREF=gi:180082 /UG=Hs.44926 dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) /FL=gb:M74777.1 M74777 dipeptidyl-peptidase 4 DPP4 1803 NM_001935 /// XM_005246371 0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211479_s_at M81778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M81778.1 /DEF=Human serotonin 5-HT1C receptor mRNA, complete cds. /FEA=mRNA /GEN=HTR1C /PROD=serotonin receptor /DB_XREF=gi:338027 /UG=Hs.46362 5-hydroxytryptamine (serotonin) receptor 2C /FL=gb:M81778.1 M81778 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled HTR2C 3358 NM_000868 /// NM_001256760 /// NM_001256761 0001662 // behavioral fear response // inferred from sequence or structural similarity /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007208 // phospholipase C-activating serotonin receptor signaling pathway // inferred from sequence or structural similarity /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from sequence or structural similarity /// 0009451 // RNA modification // inferred from electronic annotation /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0031644 // regulation of neurological system process // inferred from sequence or structural similarity /// 0032098 // regulation of appetite // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from direct assay /// 0043397 // regulation of corticotropin-releasing hormone secretion // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001587 // Gq/11-coupled serotonin receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0051378 // serotonin binding // inferred from direct assay /// 0071886 // 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding // inferred from direct assay 211480_s_at AF085224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF085224.1 /DEF=Homo sapiens brain organic anion transporter subtype OATP1b (OATP) mRNA, complete cds. /FEA=mRNA /GEN=OATP /PROD=brain organic anion transporter subtype OATP1b /DB_XREF=gi:5817298 /UG=Hs.46440 solute carrier family 21 (organic anion transporter), member 3 /FL=gb:AF085224.1 AF085224 solute carrier organic anion transporter family, member 1A2 SLCO1A2 6579 NM_005075 /// NM_021094 /// NM_134431 /// XM_005253474 /// XM_005253477 /// XM_005253478 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement 211481_at AF085224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF085224.1 /DEF=Homo sapiens brain organic anion transporter subtype OATP1b (OATP) mRNA, complete cds. /FEA=mRNA /GEN=OATP /PROD=brain organic anion transporter subtype OATP1b /DB_XREF=gi:5817298 /UG=Hs.46440 solute carrier family 21 (organic anion transporter), member 3 /FL=gb:AF085224.1 AF085224 solute carrier organic anion transporter family, member 1A2 SLCO1A2 6579 NM_005075 /// NM_021094 /// NM_134431 /// XM_005253474 /// XM_005253477 /// XM_005253478 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015711 // organic anion transport // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement 211483_x_at AF081924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF081924.1 /DEF=Homo sapiens calciumcalmodulin-dependent protein kinase II beta 6 subunit (CAMKB) mRNA, complete cds. /FEA=mRNA /GEN=CAMKB /PROD=calciumcalmodulin-dependent protein kinase IIbeta 6 subunit /DB_XREF=gi:5326761 /UG=Hs.4884 calciumcalmodulin-dependent protein kinase (CaM kinase) II beta /FL=gb:AF081924.1 AF081924 calcium/calmodulin-dependent protein kinase II beta CAMK2B 816 NM_001220 /// NM_001293170 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 /// XM_005249859 /// XM_005249861 /// XM_005249862 /// XM_005249864 /// XM_006715776 /// XM_006715777 /// XM_006715778 /// XM_006715779 /// XM_006715780 /// XM_006715781 /// XM_006715782 /// XM_006715783 /// XM_006715784 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0002030 // inhibitory G-protein coupled receptor phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032222 // regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051823 // regulation of synapse structural plasticity // traceable author statement /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060466 // activation of meiosis involved in egg activation // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // traceable author statement /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211484_s_at AF023450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF023450.1 /DEF=Homo sapiens CHD2-52 Down syndrome cell adhesion molecule (DSCAM) mRNA, complete cds. /FEA=mRNA /GEN=DSCAM /PROD=Down syndrome cell adhesion molecule /DB_XREF=gi:3169767 /UG=Hs.49002 Down syndrome cell adhesion molecule /FL=gb:AF023450.1 AF023450 Down syndrome cell adhesion molecule DSCAM 1826 NM_001271534 /// NM_001389 /// NR_073202 /// XM_006723975 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from direct assay /// 0060060 // post-embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0070593 // dendrite self-avoidance // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 211485_s_at AF211188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF211188.1 /DEF=Homo sapiens zFGF5 mRNA, complete cds. /FEA=mRNA /PROD=zFGF5 /DB_XREF=gi:6665709 /UG=Hs.49585 fibroblast growth factor 18 /FL=gb:AF211188.1 AF211188 fibroblast growth factor 18 FGF18 8817 NM_003862 /// NM_033649 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 211486_s_at AF110020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF110020.1 /DEF=Homo sapiens potassium channel (KCNQ2) mRNA, complete cds. /FEA=mRNA /GEN=KCNQ2 /PROD=potassium channel /DB_XREF=gi:4324686 /UG=Hs.4975 potassium voltage-gated channel, KQT-like subfamily, member 2 /FL=gb:AF110020.1 AF110020 potassium voltage-gated channel, KQT-like subfamily, member 2 KCNQ2 3785 NM_004518 /// NM_172106 /// NM_172107 /// NM_172108 /// NM_172109 /// XM_006723787 /// XM_006723788 /// XM_006723789 /// XM_006723790 /// XM_006723791 /// XM_006723792 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction 211487_x_at BC004886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004886.1 /DEF=Homo sapiens, ribosomal protein S17, clone MGC:11144, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S17 /DB_XREF=gi:13436139 /UG=Hs.5174 ribosomal protein S17 /FL=gb:BC004886.1 BC004886 ribosomal protein S17 RPS17 6218 NM_001021 /// NM_001199057 /// NR_111943 /// NR_111944 0000028 // ribosomal small subunit assembly // not recorded /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // not recorded /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211488_s_at BC002630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002630.1 /DEF=Homo sapiens, Similar to integrin, beta 8, clone MGC:3946, mRNA, complete cds. /FEA=mRNA /PROD=Similar to integrin, beta 8 /DB_XREF=gi:12803590 /UG=Hs.52620 integrin, beta 8 /FL=gb:BC002630.1 BC002630 integrin, beta 8 ITGB8 3696 NM_002214 /// XM_005249751 /// XM_005249752 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0060674 // placenta blood vessel development // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation 211489_at D32201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32201.1 /DEF=Human mRNA for alpha 1C adrenergic receptor isoform 3, complete cds. /FEA=mRNA /PROD=alpha 1C adrenergic receptor isoform 3 /DB_XREF=gi:927210 /UG=Hs.52931 adrenergic, alpha-1A-, receptor /FL=gb:D32201.1 D32201 adrenoceptor alpha 1A ADRA1A 148 NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 /// XM_005273414 /// XM_006716292 /// XM_006716293 0001985 // negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006939 // smooth muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007512 // adult heart development // inferred from electronic annotation /// 0007568 // aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045760 // positive regulation of action potential // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060073 // micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // non-traceable author statement /// 0071875 // adrenergic receptor signaling pathway // traceable author statement /// 0090037 // positive regulation of protein kinase C signaling // inferred from sequence or structural similarity /// 0097195 // pilomotor reflex // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from sequence or structural similarity /// 0004937 // alpha1-adrenergic receptor activity // non-traceable author statement /// 0004937 // alpha1-adrenergic receptor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 211490_at AF013261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF013261.1 /DEF=Homo sapiens alpha 1A adrenergic receptor isoform 4 mRNA, complete cds. /FEA=mRNA /PROD=alpha 1A adrenergic receptor isoform 4 /DB_XREF=gi:2978555 /UG=Hs.52931 adrenergic, alpha-1A-, receptor /FL=gb:AF013261.1 AF013261 adrenoceptor alpha 1A ADRA1A 148 NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 /// XM_005273414 /// XM_006716292 /// XM_006716293 0001985 // negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006939 // smooth muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007512 // adult heart development // inferred from electronic annotation /// 0007568 // aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045760 // positive regulation of action potential // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060073 // micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // non-traceable author statement /// 0071875 // adrenergic receptor signaling pathway // traceable author statement /// 0090037 // positive regulation of protein kinase C signaling // inferred from sequence or structural similarity /// 0097195 // pilomotor reflex // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from sequence or structural similarity /// 0004937 // alpha1-adrenergic receptor activity // non-traceable author statement /// 0004937 // alpha1-adrenergic receptor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 211491_at D32202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32202.1 /DEF=Human mRNA for alpha 1C adrenergic receptor isoform 2, complete cds. /FEA=mRNA /PROD=alpha 1C adrenergic receptor isoform 2 /DB_XREF=gi:927208 /UG=Hs.52931 adrenergic, alpha-1A-, receptor /FL=gb:D32202.1 D32202 adrenoceptor alpha 1A ADRA1A 148 NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 /// XM_005273414 /// XM_006716292 /// XM_006716293 0001985 // negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006939 // smooth muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007512 // adult heart development // inferred from electronic annotation /// 0007568 // aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045760 // positive regulation of action potential // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060073 // micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // non-traceable author statement /// 0071875 // adrenergic receptor signaling pathway // traceable author statement /// 0090037 // positive regulation of protein kinase C signaling // inferred from sequence or structural similarity /// 0097195 // pilomotor reflex // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from sequence or structural similarity /// 0004937 // alpha1-adrenergic receptor activity // non-traceable author statement /// 0004937 // alpha1-adrenergic receptor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 211492_s_at U02569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U02569.1 /DEF=Human alpha1C adrenergic receptor mRNA, complete cds. /FEA=mRNA /PROD=alpha1C adrenergic receptor /DB_XREF=gi:409028 /UG=Hs.52931 adrenergic, alpha-1A-, receptor /FL=gb:U02569.1 gb:D25235.1 gb:NM_000680.1 gb:L31774.1 U02569 adrenoceptor alpha 1A ADRA1A 148 NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 /// XM_005273414 /// XM_006716292 /// XM_006716293 0001985 // negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0001994 // norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001996 // positive regulation of heart rate by epinephrine-norepinephrine // inferred from electronic annotation /// 0001997 // positive regulation of the force of heart contraction by epinephrine-norepinephrine // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006939 // smooth muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007512 // adult heart development // inferred from electronic annotation /// 0007568 // aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045760 // positive regulation of action potential // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060073 // micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0071875 // adrenergic receptor signaling pathway // non-traceable author statement /// 0071875 // adrenergic receptor signaling pathway // traceable author statement /// 0090037 // positive regulation of protein kinase C signaling // inferred from sequence or structural similarity /// 0097195 // pilomotor reflex // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004937 // alpha1-adrenergic receptor activity // inferred from sequence or structural similarity /// 0004937 // alpha1-adrenergic receptor activity // non-traceable author statement /// 0004937 // alpha1-adrenergic receptor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 211493_x_at U46744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U46744.1 /DEF=Human dystrobrevin-alpha mRNA, complete cds. /FEA=mRNA /PROD=dystrobrevin-alpha /DB_XREF=gi:1256010 /UG=Hs.54435 dystrobrevin, alpha /FL=gb:U46744.1 U46744 dystrobrevin, alpha DTNA 1837 NM_001128175 /// NM_001198938 /// NM_001198939 /// NM_001198940 /// NM_001198941 /// NM_001198942 /// NM_001198943 /// NM_001198944 /// NM_001198945 /// NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 /// XM_005258207 /// XM_005258212 /// XM_005258216 /// XM_005258217 /// XM_005258218 /// XM_005258219 /// XM_005258220 /// XM_005258221 /// XM_005258222 /// XM_005258223 /// XM_005258224 /// XM_006722395 /// XM_006722396 /// XM_006722397 /// XM_006722398 /// XM_006722399 /// XM_006722400 /// XM_006722401 /// XM_006722402 /// XM_006722403 /// XM_006722404 /// XM_006722405 /// XM_006722406 /// XM_006722407 /// XM_006722408 /// XM_006722409 /// XM_006722410 /// XM_006722411 /// XM_006722412 /// XM_006722413 /// XM_006722414 /// XM_006722415 0006941 // striated muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007274 // neuromuscular synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211494_s_at AF157492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF157492.1 /DEF=Homo sapiens sodium bicarbonate cotransporter NBC1 (SLC4A4) mRNA, alternatively spliced product, complete cds. /FEA=mRNA /GEN=SLC4A4 /PROD=sodium bicarbonate cotransporter NBC1 /DB_XREF=gi:8886014 /UG=Hs.5462 solute carrier family 4, sodium bicarbonate cotransporter, member 4 /FL=gb:AF157492.1 AF157492 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 SLC4A4 8671 NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 211495_x_at AF114011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF114011.1 /DEF=Homo sapiens tumor necrosis factor-related death ligand-1alpha mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor-related deathligand-1alpha /DB_XREF=gi:7328553 /UG=Hs.54673 tumor necrosis factor (ligand) superfamily, member 13 /FL=gb:AF046888.1 gb:NM_003808.1 gb:AF184972.1 gb:AF114011.1 AF114011 TNFSF12-TNFSF13 readthrough /// tumor necrosis factor (ligand) superfamily, member 13 TNFSF12-TNFSF13 /// TNFSF13 8741 /// 407977 NM_001198622 /// NM_001198623 /// NM_001198624 /// NM_003808 /// NM_172087 /// NM_172088 /// NM_172089 /// NR_073490 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 211496_s_at M33478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33478.1 /DEF=Human 33-kDa phototransducing protein mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:177186 /UG=Hs.550 phosducin /FL=gb:NM_022577.1 gb:M33478.1 gb:AF076465.1 M33478 phosducin PDC 5132 NM_002597 /// NM_022576 /// NM_022577 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // traceable author statement 211497_x_at AF249671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF249671.1 /DEF=Homo sapiens homeodomain protein NKX3.1 isoform v3 (NKX3A) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=NKX3A /PROD=homeodomain protein NKX3.1 isoform v3 /DB_XREF=gi:11692276 /UG=Hs.55999 NK homeobox (Drosophila), family 3, A /FL=gb:AF249671.1 AF249671 NK3 homeobox 1 NKX3-1 4824 NM_001256339 /// NM_006167 /// NR_046072 0001655 // urogenital system development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0007431 // salivary gland development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from sequence or structural similarity /// 0035690 // cellular response to drug // inferred from expression pattern /// 0035907 // dorsal aorta development // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071850 // mitotic cell cycle arrest // inferred from direct assay /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 2000836 // positive regulation of androgen secretion // inferred from direct assay /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004882 // androgen receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0097162 // MADS box domain binding // inferred from electronic annotation 211498_s_at AF249669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF249669.1 /DEF=Homo sapiens homeodomain protein NKX3.1 isoform v1 (NKX3A) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=NKX3A /PROD=homeodomain protein NKX3.1 isoform v1 /DB_XREF=gi:11692272 /UG=Hs.55999 NK homeobox (Drosophila), family 3, A /FL=gb:AF249669.1 AF249669 NK3 homeobox 1 NKX3-1 4824 NM_001256339 /// NM_006167 /// NR_046072 0001655 // urogenital system development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0007431 // salivary gland development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from sequence or structural similarity /// 0035690 // cellular response to drug // inferred from expression pattern /// 0035907 // dorsal aorta development // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071850 // mitotic cell cycle arrest // inferred from direct assay /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 2000836 // positive regulation of androgen secretion // inferred from direct assay /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004882 // androgen receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0097162 // MADS box domain binding // inferred from electronic annotation 211499_s_at U92268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U92268.1 /DEF=Homo sapiens mitogen activated protein kinase p38-2 mRNA, complete cds. /FEA=mRNA /PROD=mitogen activated protein kinase p38-2 /DB_XREF=gi:2316011 /UG=Hs.57732 mitogen-activated protein kinase 11 /FL=gb:U92268.1 U92268 mitogen-activated protein kinase 11 MAPK11 5600 NM_002751 /// NR_110887 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 211500_at U53442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U53442.1 /DEF=Human p38Beta MAP kinase mRNA, complete cds. /FEA=mRNA /PROD=p38Beta MAP kinase /DB_XREF=gi:1469305 /UG=Hs.57732 mitogen-activated protein kinase 11 /FL=gb:U53442.1 U53442 mitogen-activated protein kinase 11 MAPK11 5600 NM_002751 /// NR_110887 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 211501_s_at BC001173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001173.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD), clone MGC:2051, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 3,subunit 9 (eta, 116kD) /DB_XREF=gi:12654668 /UG=Hs.57783 eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) /FL=gb:BC001173.1 BC001173 eukaryotic translation initiation factor 3, subunit B EIF3B 8662 NM_001037283 /// NM_003751 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // traceable author statement 211502_s_at AF119833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119833.1 /DEF=Homo sapiens serinethreonine protein kinase PFTAIRE-1 mRNA, complete cds. /FEA=mRNA /PROD=serinethreonine protein kinase PFTAIRE-1 /DB_XREF=gi:12002200 /UG=Hs.57856 PFTAIRE protein kinase 1 /FL=gb:AF119833.1 AF119833 cyclin-dependent kinase 14 CDK14 5218 NM_001287135 /// NM_001287136 /// NM_001287137 /// NM_012395 /// XM_005250435 /// XM_005250436 /// XM_005250438 /// XM_005250439 /// XM_006716026 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0060828 // regulation of canonical Wnt signaling pathway // inferred from direct assay 0000308 // cytoplasmic cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 211503_s_at AF112206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112206.1 /DEF=Homo sapiens ras-related protein rab-14 mRNA, complete cds. /FEA=mRNA /PROD=ras-related protein rab-14 /DB_XREF=gi:6563199 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF112206.1 AF112206 RAB14, member RAS oncogene family RAB14 51552 NM_016322 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0006895 // Golgi to endosome transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0046907 // intracellular transport // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 211504_x_at D87931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87931.1 /DEF=Homo sapiens mRNA for Rho kinase, complete cds. /FEA=mRNA /PROD=Rho kinase /DB_XREF=gi:4520224 /UG=Hs.58617 Rho-associated, coiled-coil containing protein kinase 2 /FL=gb:D87931.1 D87931 Rho-associated, coiled-coil containing protein kinase 2 ROCK2 9475 NM_004850 /// XM_005246190 0000910 // cytokinesis // non-traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006939 // smooth muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0010825 // positive regulation of centrosome duplication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // traceable author statement /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045616 // regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 2000114 // regulation of establishment of cell polarity // traceable author statement /// 2000145 // regulation of cell motility // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211505_s_at AL136601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136601.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J1516 (from clone DKFZp564J1516); complete cds. /FEA=mRNA /GEN=DKFZp564J1516 /PROD=hypothetical protein /DB_XREF=gi:13276702 /UG=Hs.6113 staufen (Drosophila, RNA-binding protein) /FL=gb:AL136601.1 AL136601 staufen double-stranded RNA binding protein 1 STAU1 6780 NM_001037328 /// NM_004602 /// NM_017452 /// NM_017453 /// NM_017454 /// XM_005260524 /// XM_005260525 /// XM_005260526 /// XM_005260527 /// XM_005260528 /// XM_005260529 /// XM_006723865 /// XM_006723866 /// XM_006723867 /// XM_006723868 /// XM_006723869 0008298 // intracellular mRNA localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211506_s_at AF043337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043337.1 /DEF=Homo sapiens interleukin 8 C-terminal variant (IL8) mRNA, complete cds. /FEA=mRNA /GEN=IL8 /PROD=interleukin 8 C-terminal variant /DB_XREF=gi:12641914 /UG=Hs.624 interleukin 8 /FL=gb:AF043337.1 AF043337 chemokine (C-X-C motif) ligand 8 CXCL8 3576 NM_000584 0001525 // angiogenesis // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from genetic interaction /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031623 // receptor internalization // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042119 // neutrophil activation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045091 // regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0050930 // induction of positive chemotaxis // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0090023 // positive regulation of neutrophil chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005153 // interleukin-8 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // traceable author statement 211507_s_at AF233437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF233437.1 /DEF=Homo sapiens FYVE domain-containing dual specificity protein phosphatase FYVE-DSP1b mRNA, complete cds. /FEA=mRNA /PROD=FYVE domain-containing dual specificity proteinphosphatase FYVE-DSP1b /DB_XREF=gi:7208445 /UG=Hs.63302 myotubularin related protein 3 /FL=gb:AF233437.1 AF233437 myotubularin related protein 3 MTMR3 8897 NM_001013676 /// NM_021090 /// NM_153050 /// NM_153051 /// XM_005261803 /// XM_005261804 /// XM_005261805 /// XM_005261806 /// XM_005261807 /// XM_005261808 /// XM_005261809 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211508_s_at AF006060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006060.1 /DEF=Homo sapiens placental growth hormone 20kDa isoform (hGH-V) mRNA, complete cds. /FEA=mRNA /GEN=hGH-V /PROD=placental growth hormone 20kDa isoform /DB_XREF=gi:2459881 /UG=Hs.65149 growth hormone 2 /FL=gb:NM_022556.1 gb:AF006060.1 AF006060 growth hormone 2 GH2 2689 NM_002059 /// NM_022556 /// NM_022557 /// NM_022558 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 211509_s_at AB015639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB015639.1 /DEF=Homo sapiens ASY mRNA, complete cds. /FEA=mRNA /GEN=ASY /DB_XREF=gi:5821139 /UG=Hs.65450 reticulon 4 /FL=gb:AB015639.1 AB015639 reticulon 4 RTN4 57142 NM_007008 /// NM_020532 /// NM_153828 /// NM_207520 /// NM_207521 /// XM_005264434 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0021801 // cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from direct assay /// 0030517 // negative regulation of axon extension // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0051960 // regulation of nervous system development // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from sequence or structural similarity 0005622 // intracellular // inferred from mutant phenotype /// 0005635 // nuclear envelope // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211510_s_at AF019381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF019381.1 /DEF=Homo sapiens corticotropin releasing hormone receptor type 2 gamma isoform (CRH2R) mRNA, complete cds. /FEA=mRNA /GEN=CRH2R /PROD=corticotropin releasing hormone receptor type 2gamma isoform /DB_XREF=gi:2738888 /UG=Hs.66578 corticotropin releasing hormone receptor 2 /FL=gb:AF019381.1 AF019381 corticotropin releasing hormone receptor 2 CRHR2 1395 NM_001202475 /// NM_001202481 /// NM_001202482 /// NM_001202483 /// NM_001883 /// XM_006715651 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0071376 // cellular response to corticotropin-releasing hormone stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015056 // corticotrophin-releasing factor receptor activity // inferred from electronic annotation 211512_s_at AF172450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF172450.1 /DEF=Homo sapiens opioid growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=opioid growth factor receptor /DB_XREF=gi:7595300 /UG=Hs.67896 7-60 protein /FL=gb:AF172450.1 AF172450 opioid growth factor receptor OGFR 11054 NM_007346 0001558 // regulation of cell growth // non-traceable author statement /// 0038003 // opioid receptor signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // non-traceable author statement 211513_s_at AF172449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF172449.1 /DEF=Homo sapiens clone 127 opioid growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=opioid growth factor receptor /DB_XREF=gi:7595298 /UG=Hs.67896 7-60 protein /FL=gb:AF172449.1 AF172449 opioid growth factor receptor OGFR 11054 NM_007346 0001558 // regulation of cell growth // non-traceable author statement /// 0038003 // opioid receptor signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // non-traceable author statement 211514_at AF068286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068286.1 /DEF=Homo sapiens HDCMD38P mRNA, complete cds. /FEA=mRNA /PROD=HDCMD38P /DB_XREF=gi:7643779 /UG=Hs.6874 KIAA0472 protein /FL=gb:AF068286.1 AF068286 dual serine/threonine and tyrosine protein kinase DSTYK 25778 NM_015375 /// NM_199462 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211515_s_at AF068286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF068286.1 /DEF=Homo sapiens HDCMD38P mRNA, complete cds. /FEA=mRNA /PROD=HDCMD38P /DB_XREF=gi:7643779 /UG=Hs.6874 KIAA0472 protein /FL=gb:AF068286.1 AF068286 dual serine/threonine and tyrosine protein kinase DSTYK 25778 NM_015375 /// NM_199462 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211516_at M96651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M96651.1 /DEF=Human interleukin 5 receptor alpha-subunit (IL5R) mRNA, complete cds. /FEA=mRNA /GEN=IL5R /PROD=interleukin 5 receptor alpha-subunit /DB_XREF=gi:186342 /UG=Hs.68876 interleukin 5 receptor, alpha /FL=gb:M96651.1 M96651 interleukin 5 receptor, alpha IL5RA 3568 NM_000564 /// NM_001243099 /// NM_175724 /// NM_175725 /// NM_175726 /// NM_175727 /// NM_175728 /// XM_006713127 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032674 // regulation of interleukin-5 production // inferred from electronic annotation /// 0038043 // interleukin-5-mediated signaling pathway // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005895 // interleukin-5 receptor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004914 // interleukin-5 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211517_s_at M96651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M96651.1 /DEF=Human interleukin 5 receptor alpha-subunit (IL5R) mRNA, complete cds. /FEA=mRNA /GEN=IL5R /PROD=interleukin 5 receptor alpha-subunit /DB_XREF=gi:186342 /UG=Hs.68876 interleukin 5 receptor, alpha /FL=gb:M96651.1 M96651 interleukin 5 receptor, alpha IL5RA 3568 NM_000564 /// NM_001243099 /// NM_175724 /// NM_175725 /// NM_175726 /// NM_175727 /// NM_175728 /// XM_006713127 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032674 // regulation of interleukin-5 production // inferred from electronic annotation /// 0038043 // interleukin-5-mediated signaling pathway // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005895 // interleukin-5 receptor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004914 // interleukin-5 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211518_s_at D30751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D30751.1 /DEF=Human placenta mRNA for bone morphogenetic protein 4 (BMP-4), complete cds. /FEA=mRNA /GEN=BMP-4 /PROD=bone morphogenetic protein 4 /DB_XREF=gi:576934 /UG=Hs.68879 bone morphogenetic protein 4 /FL=gb:D30751.1 D30751 bone morphogenetic protein 4 BMP4 652 NM_001202 /// NM_130850 /// NM_130851 /// XM_005268015 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from direct assay /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001822 // kidney development // inferred from mutant phenotype /// 0001823 // mesonephros development // inferred from expression pattern /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001944 // vasculature development // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0002320 // lymphoid progenitor cell differentiation // inferred from mutant phenotype /// 0003014 // renal system process // inferred from electronic annotation /// 0003130 // BMP signaling pathway involved in heart induction // inferred from mutant phenotype /// 0003139 // secondary heart field specification // inferred from mutant phenotype /// 0003197 // endocardial cushion development // traceable author statement /// 0003279 // cardiac septum development // traceable author statement /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from direct assay /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007500 // mesodermal cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009791 // post-embryonic development // inferred from direct assay /// 0009888 // tissue development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010159 // specification of organ position // inferred from electronic annotation /// 0010453 // regulation of cell fate commitment // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0021537 // telencephalon development // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021978 // telencephalon regionalization // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030225 // macrophage differentiation // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0033085 // negative regulation of T cell differentiation in thymus // inferred from mutant phenotype /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035990 // tendon cell differentiation // inferred from sequence or structural similarity /// 0035993 // deltoid tuberosity development // inferred from sequence or structural similarity /// 0040007 // growth // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from genetic interaction /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045606 // positive regulation of epidermal cell differentiation // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0045843 // negative regulation of striated muscle tissue development // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048286 // lung alveolus development // inferred from direct assay /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048392 // intermediate mesodermal cell differentiation // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055020 // positive regulation of cardiac muscle fiber development // inferred from mutant phenotype /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060425 // lung morphogenesis // inferred from direct assay /// 0060429 // epithelium development // inferred from electronic annotation /// 0060433 // bronchus development // inferred from direct assay /// 0060438 // trachea development // inferred from direct assay /// 0060440 // trachea formation // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from direct assay /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060449 // bud elongation involved in lung branching // inferred from electronic annotation /// 0060502 // epithelial cell proliferation involved in lung morphogenesis // inferred from direct assay /// 0060503 // bud dilation involved in lung branching // inferred from direct assay /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060592 // mammary gland formation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060688 // regulation of morphogenesis of a branching structure // inferred from electronic annotation /// 0061035 // regulation of cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0061047 // positive regulation of branching involved in lung morphogenesis // inferred from sequence or structural similarity /// 0061149 // BMP signaling pathway involved in ureter morphogenesis // inferred from sequence or structural similarity /// 0061151 // BMP signaling pathway involved in renal system segmentation // inferred from sequence or structural similarity /// 0061155 // pulmonary artery endothelial tube morphogenesis // inferred from direct assay /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071893 // BMP signaling pathway involved in nephric duct formation // inferred from direct assay /// 0072001 // renal system development // inferred from expression pattern /// 0072015 // glomerular visceral epithelial cell development // inferred from electronic annotation /// 0072097 // negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway // inferred from direct assay /// 0072101 // specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway // inferred from direct assay /// 0072104 // glomerular capillary formation // inferred from sequence or structural similarity /// 0072125 // negative regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from electronic annotation /// 0072161 // mesenchymal cell differentiation involved in kidney development // inferred from electronic annotation /// 0072192 // ureter epithelial cell differentiation // inferred from sequence or structural similarity /// 0072193 // ureter smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0072198 // mesenchymal cell proliferation involved in ureter development // inferred from electronic annotation /// 0072200 // negative regulation of mesenchymal cell proliferation involved in ureter development // inferred from direct assay /// 0072205 // metanephric collecting duct development // inferred from sequence or structural similarity /// 0090184 // positive regulation of kidney development // inferred from direct assay /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from direct assay /// 0090194 // negative regulation of glomerulus development // inferred from direct assay /// 2000005 // negative regulation of metanephric S-shaped body morphogenesis // inferred from direct assay /// 2000007 // negative regulation of metanephric comma-shaped body morphogenesis // inferred from direct assay /// 2000105 // positive regulation of DNA-dependent DNA replication // inferred from direct assay /// 2000137 // negative regulation of cell proliferation involved in heart morphogenesis // inferred from mutant phenotype /// 2001012 // mesenchymal cell differentiation involved in renal system development // inferred from electronic annotation 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from direct assay 211519_s_at AY026505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY026505.1 /DEF=Homo sapiens testis specific mitotic centromere-associated kinesin mRNA, complete cds. /FEA=mRNA /PROD=testis specific mitotic centromere-associatedkinesin /DB_XREF=gi:13432054 /UG=Hs.69360 kinesin-like 6 (mitotic centromere-associated kinesin) /FL=gb:AY026505.1 AY026505 kinesin family member 2C KIF2C 11004 NM_006845 /// XM_005270394 /// XM_005270395 /// XM_005270396 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007019 // microtubule depolymerization // inferred from direct assay /// 0007019 // microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019237 // centromeric DNA binding // traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 211520_s_at M64752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M64752.1 /DEF=Human glutamate receptor subunit (GluH1) mRNA, complete cds. /FEA=mRNA /GEN=GluH1 /PROD=glutamate receptor subunit /DB_XREF=gi:183280 /UG=Hs.7117 glutamate receptor, ionotropic, AMPA 1 /FL=gb:M64752.1 M64752 glutamate receptor, ionotropic, AMPA 1 GRIA1 2890 NM_000827 /// NM_001114183 /// NM_001258019 /// NM_001258020 /// NM_001258021 /// NM_001258022 /// NM_001258023 /// NR_047578 /// XR_427776 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0008328 // ionotropic glutamate receptor complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0044309 // neuron spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008066 // glutamate receptor activity // traceable author statement /// 0015277 // kainate selective glutamate receptor activity // traceable author statement /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 211521_s_at AF125349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125349.1 /DEF=Homo sapiens guanine nucleotide exchange factor cytohesin-4p mRNA, complete cds. /FEA=mRNA /PROD=guanine nucleotide exchange factor cytohesin-4p /DB_XREF=gi:6841085 /UG=Hs.7189 pleckstrin homology, Sec7 and coiledcoil domains 4 /FL=gb:AF125349.1 AF125349 cytohesin 4 CYTH4 27128 NM_013385 /// XR_430406 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 211522_s_at L03380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L03380.1 /DEF=Human gonadotropin-releasing hormone receptor mRNA, complete cds. /FEA=mRNA /PROD=gonadotropin-releasing hormone receptor /DB_XREF=gi:183421 /UG=Hs.73064 gonadotropin-releasing hormone receptor /FL=gb:L03380.1 gb:L07949.1 gb:NM_000406.1 L03380 gonadotropin-releasing hormone receptor GNRHR 2798 NM_000406 /// NM_001012763 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0097211 // cellular response to gonadotropin-releasing hormone // inferred from electronic annotation /// 0097211 // cellular response to gonadotropin-releasing hormone // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004968 // gonadotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 211523_at L07949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L07949.1 /DEF=Homo sapiens GnRH receptor mRNA, complete cds. /FEA=mRNA /PROD=GnRH receptor /DB_XREF=gi:292052 /UG=Hs.73064 gonadotropin-releasing hormone receptor /FL=gb:L03380.1 gb:L07949.1 gb:NM_000406.1 L07949 gonadotropin-releasing hormone receptor GNRHR 2798 NM_000406 /// NM_001012763 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0097211 // cellular response to gonadotropin-releasing hormone // inferred from electronic annotation /// 0097211 // cellular response to gonadotropin-releasing hormone // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004968 // gonadotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 211524_at U09609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U09609.1 /DEF=Human p80HT (p80HTNKFB-2) mRNA, complete cds. /FEA=mRNA /GEN=p80HTNKFB-2 /PROD=p80HT /DB_XREF=gi:495193 /UG=Hs.73090 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49p100) /FL=gb:U09609.1 U09609 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) NFKB2 4791 NM_001077494 /// NM_001261403 /// NM_001288724 /// NM_002502 /// XM_005269860 /// XM_005269861 /// XM_006717869 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002268 // follicular dendritic cell differentiation // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048536 // spleen development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0033257 // Bcl3/NF-kappaB2 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211525_s_at L11238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11238.1 /DEF=Homo sapiens platelet membrane glycoprotein V mRNA, complete cds. /FEA=mRNA /PROD=platelet membrane glycoprotein V /DB_XREF=gi:388759 /UG=Hs.73734 glycoprotein V (platelet) /FL=gb:L11238.1 L11238 glycoprotein V (platelet) GP5 2814 NM_004488 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation 211526_s_at BC000673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000673.1 /DEF=Homo sapiens, Similar to helicase-like protein NHL, clone MGC:665, mRNA, complete cds. /FEA=mRNA /PROD=Similar to helicase-like protein NHL /DB_XREF=gi:12653774 /UG=Hs.73742 ribosomal protein, large, P0 /FL=gb:BC000673.1 BC000673 regulator of telomere elongation helicase 1 /// RTEL1-TNFRSF6B readthrough (NMD candidate) RTEL1 /// RTEL1-TNFRSF6B 51750 /// 100533107 NM_001283009 /// NM_001283010 /// NM_016434 /// NM_032957 /// NR_037882 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from sequence or structural similarity /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 211527_x_at M27281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M27281.1 /DEF=Human vascular permeability factor mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:340300 /UG=Hs.73793 vascular endothelial growth factor /FL=gb:M27281.1 M27281 vascular endothelial growth factor A VEGFA 7422 NM_001025366 /// NM_001025367 /// NM_001025368 /// NM_001025369 /// NM_001025370 /// NM_001033756 /// NM_001171622 /// NM_001171623 /// NM_001171624 /// NM_001171625 /// NM_001171626 /// NM_001171627 /// NM_001171628 /// NM_001171629 /// NM_001171630 /// NM_001204384 /// NM_001204385 /// NM_001287044 /// NM_003376 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0002575 // basophil chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // traceable author statement /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003169 // coronary vein morphogenesis // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009409 // response to cold // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030225 // macrophage differentiation // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0031077 // post-embryonic camera-type eye development // inferred from sequence or structural similarity /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032793 // positive regulation of CREB transcription factor activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035148 // tube formation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036303 // lymph vessel morphogenesis // inferred from sequence or structural similarity /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0040007 // growth // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060319 // primitive erythrocyte differentiation // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060948 // cardiac vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090037 // positive regulation of protein kinase C signaling // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901492 // positive regulation of lymphangiogenesis // inferred from electronic annotation /// 1901727 // positive regulation of histone deacetylase activity // inferred from direct assay /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay /// 1902966 // positive regulation of protein localization to early endosome // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0001968 // fibronectin binding // inferred from direct assay /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005172 // vascular endothelial growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0038191 // neuropilin binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred by curator 211528_x_at M90685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90685.1 /DEF=Human lymphocyte antigen (HLA-G2.2) mRNA, complete cds. /FEA=mRNA /GEN=HLA-G2.2 /PROD=b2 microglobulin /DB_XREF=gi:184211 /UG=Hs.73885 HLA-G histocompatibility antigen, class I, G /FL=gb:M90685.1 M90685 major histocompatibility complex, class I, G HLA-G 3135 NM_002127 /// XM_006715080 /// XM_006725041 /// XM_006725700 /// XM_006725909 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001199 // negative regulation of dendritic cell differentiation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042803 // protein homodimerization activity // non-traceable author statement 211529_x_at M90684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90684.1 /DEF=Human lymphocyte antigen (HLA-G2.1) mRNA, complete cds. /FEA=mRNA /GEN=HLA-G /PROD=b2 microglobulin /DB_XREF=gi:188467 /UG=Hs.73885 HLA-G histocompatibility antigen, class I, G /FL=gb:M90684.1 M90684 major histocompatibility complex, class I, G HLA-G 3135 NM_002127 /// XM_006715080 /// XM_006725041 /// XM_006725700 /// XM_006725909 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001199 // negative regulation of dendritic cell differentiation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042803 // protein homodimerization activity // non-traceable author statement 211530_x_at M90686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90686.1 /DEF=Human lymphocyte antigen (HLA-G3) mRNA, complete cds. /FEA=mRNA /GEN=HLA-G3 /PROD=b2 microglobulin /DB_XREF=gi:184213 /UG=Hs.73885 HLA-G histocompatibility antigen, class I, G /FL=gb:M90686.1 M90686 major histocompatibility complex, class I, G HLA-G 3135 NM_002127 /// XM_006715080 /// XM_006725041 /// XM_006725700 /// XM_006725909 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002666 // positive regulation of T cell tolerance induction // inferred from mutant phenotype /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001199 // negative regulation of dendritic cell differentiation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0042803 // protein homodimerization activity // non-traceable author statement 211531_x_at K03205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03205.1 /DEF=Human PRB1 locus salivary proline-rich protein mRNA, clone cP4, complete cds. /FEA=mRNA /GEN=PRB1 /DB_XREF=gi:190503 /UG=Hs.73953 proline-rich protein BstNI subfamily 2 /FL=gb:K03205.1 K03205 proline-rich protein BstNI subfamily 1 PRB1 5542 NM_005039 /// NM_199353 /// NM_199354 0005576 // extracellular region // inferred from electronic annotation 211532_x_at L76668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L76668.1 /DEF=Homo sapiens nkat5-delta-Ig1 mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:1217722 /UG=Hs.74134 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 /FL=gb:L76668.1 L76668 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 KIR2DS2 100132285 NM_001291695 /// NM_001291696 /// NM_001291700 /// NM_001291701 /// NM_012312 /// XM_006725429 /// XM_006725653 /// XM_006725789 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0032393 // MHC class I receptor activity // non-traceable author statement 211533_at M22734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M22734.1 /DEF=Human platelet-derived growth factor A type receptor mRNA, complete cds. /FEA=mRNA /GEN=PDGFA /PROD=platelet-derived growth factor A receptor /DB_XREF=gi:189725 /UG=Hs.74615 platelet-derived growth factor receptor, alpha polypeptide /FL=gb:M22734.1 M22734 platelet-derived growth factor receptor, alpha polypeptide PDGFRA 5156 NM_006206 /// XM_005265743 /// XM_006714039 /// XM_006714040 /// XM_006714041 0001553 // luteinization // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030539 // male genitalia development // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035790 // platelet-derived growth factor receptor-alpha signaling pathway // inferred from mutant phenotype /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2000739 // regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from mutant phenotype /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 211534_x_at U65065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U65065.1 /DEF=Human tyrosine phosphatase IA-2beta mRNA, complete cds. /FEA=mRNA /PROD=tyrosine phosphatase IA-2beta /DB_XREF=gi:2281288 /UG=Hs.74624 protein tyrosine phosphatase, receptor type, N polypeptide 2 /FL=gb:U65065.1 U65065 protein tyrosine phosphatase, receptor type, N polypeptide 2 PTPRN2 5799 NM_002847 /// NM_130842 /// NM_130843 /// XM_006716075 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 211535_s_at M60485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60485.1 /DEF=Human fibroblast growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=fibroblast growth factor receptor /DB_XREF=gi:182560 /UG=Hs.748 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) /FL=gb:M60485.1 M60485 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211536_x_at AB009358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009358.2 /DEF=Homo sapiens mRNA for TGF-beta activated kinase 1c, complete cds. /FEA=mRNA /PROD=TGF-beta activated kinase 1c /DB_XREF=gi:8978251 /UG=Hs.7510 mitogen-activated protein kinase kinase kinase 7 /FL=gb:AB009358.2 AB009358 mitogen-activated protein kinase kinase kinase 7 MAP3K7 6885 NM_003188 /// NM_145331 /// NM_145332 /// NM_145333 /// XM_006715553 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from direct assay 211537_x_at AF218074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF218074.1 /DEF=Homo sapiens TGF beta-activated kinase splice variant d (TAK1) mRNA, complete cds. /FEA=mRNA /GEN=TAK1 /PROD=TGF beta-activated kinase splice variant d /DB_XREF=gi:6746614 /UG=Hs.7510 mitogen-activated protein kinase kinase kinase 7 /FL=gb:AF218074.1 AF218074 mitogen-activated protein kinase kinase kinase 7 MAP3K7 6885 NM_003188 /// NM_145331 /// NM_145332 /// NM_145333 /// XM_006715553 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002726 // positive regulation of T cell cytokine production // inferred from mutant phenotype /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from direct assay 211538_s_at U56725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U56725.1 /DEF=Human heat shock protein mRNA, complete cds. /FEA=mRNA /PROD=heat shock protein /DB_XREF=gi:4204879 /UG=Hs.75452 heat shock 70kD protein 2 /FL=gb:U56725.1 U56725 heat shock 70kDa protein 2 HSPA2 3306 NM_021979 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007140 // male meiosis // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0031662 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay /// 0070194 // synaptonemal complex disassembly // inferred from electronic annotation /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0000795 // synaptonemal complex // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0036128 // CatSper complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051861 // glycolipid binding // inferred from electronic annotation 211540_s_at M19701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M19701.1 /DEF=Human mutated retinoblastoma susceptibility (RB) mRNA, complete cds. /FEA=mRNA /GEN=RB1 /DB_XREF=gi:190967 /UG=Hs.75770 retinoblastoma 1 (including osteosarcoma) /FL=gb:M19701.1 M19701 retinoblastoma 1 RB1 5925 NM_000321 0000075 // cell cycle checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from physical interaction /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031134 // sister chromatid biorientation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from mutant phenotype /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071459 // protein localization to chromosome, centromeric region // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0090230 // regulation of centromere complex assembly // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016514 // SWI/SNF complex // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0035189 // Rb-E2F complex // traceable author statement 0001047 // core promoter binding // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0051219 // phosphoprotein binding // inferred from physical interaction 211541_s_at U52373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U52373.1 /DEF=Human serinethreonine kinase MNB (mnb) mRNA, complete cds. /FEA=mRNA /GEN=mnb /PROD=MNB /DB_XREF=gi:1663725 /UG=Hs.75842 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A /FL=gb:U58496.1 gb:U52373.1 gb:NM_001396.1 U52373 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DYRK1A 1859 NM_001396 /// NM_101395 /// NM_130436 /// NM_130437 /// NM_130438 /// XM_005260931 /// XM_005260933 /// XM_006723976 /// XM_006723977 /// XM_006723978 /// XM_006723979 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0090312 // positive regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043621 // protein self-association // inferred from sequence or structural similarity /// 0048156 // tau protein binding // inferred from sequence or structural similarity 211542_x_at BC004334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004334.1 /DEF=Homo sapiens, ribosomal protein S10, clone MGC:10943, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S10 /DB_XREF=gi:13279259 /UG=Hs.76230 ribosomal protein S10 /FL=gb:BC004334.1 BC004334 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 211543_s_at AF040752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF040752.1 /DEF=Homo sapiens G protein-coupled receptor kinase 6, splice variant C (GRK6) mRNA, complete cds. /FEA=mRNA /GEN=GRK6 /PROD=G protein-coupled receptor kinase 6, splicevariant C /DB_XREF=gi:3005017 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:AF040752.1 AF040752 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211544_s_at AB058895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB058895.1 /DEF=Homo sapiens GHRHRpsv mRNA for growth hormone releasing hormone receptor pituitary splice variant, complete cds. /FEA=mRNA /GEN=GHRHRpsv /PROD=growth hormone releasing hormone receptorpituitary splice variant /DB_XREF=gi:13488768 /UG=Hs.767 growth hormone releasing hormone receptor /FL=gb:AB058895.1 AB058895 growth hormone releasing hormone receptor GHRHR 2692 NM_000823 /// NM_001009824 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033143 // regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // non-traceable author statement /// 0043627 // response to estrogen // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // non-traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0060124 // positive regulation of growth hormone secretion // non-traceable author statement /// 0060133 // somatotropin secreting cell development // inferred from electronic annotation 0005637 // nuclear inner membrane // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0016520 // growth hormone-releasing hormone receptor activity // inferred from mutant phenotype /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction 211545_at AB058895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB058895.1 /DEF=Homo sapiens GHRHRpsv mRNA for growth hormone releasing hormone receptor pituitary splice variant, complete cds. /FEA=mRNA /GEN=GHRHRpsv /PROD=growth hormone releasing hormone receptorpituitary splice variant /DB_XREF=gi:13488768 /UG=Hs.767 growth hormone releasing hormone receptor /FL=gb:AB058895.1 AB058895 growth hormone releasing hormone receptor GHRHR 2692 NM_000823 /// NM_001009824 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033143 // regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // non-traceable author statement /// 0043627 // response to estrogen // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // non-traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0060124 // positive regulation of growth hormone secretion // non-traceable author statement /// 0060133 // somatotropin secreting cell development // inferred from electronic annotation 0005637 // nuclear inner membrane // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0016520 // growth hormone-releasing hormone receptor activity // inferred from mutant phenotype /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction 211546_x_at L36674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L36674.1 /DEF=Human (clone 2-5) synuclein (NACP) mRNA, complete cds. /FEA=mRNA /GEN=NACP /PROD=synuclein /DB_XREF=gi:556211 /UG=Hs.76930 synuclein, alpha (non A4 component of amyloid precursor) /FL=gb:L36674.1 L36674 synuclein, alpha (non A4 component of amyloid precursor) SNCA 6622 NM_000345 /// NM_001146054 /// NM_001146055 /// NM_007308 0001774 // microglial cell activation // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006638 // neutral lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from direct assay /// 0010517 // regulation of phospholipase activity // inferred from direct assay /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014048 // regulation of glutamate secretion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032769 // negative regulation of monooxygenase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from electronic annotation /// 0043030 // regulation of macrophage activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from direct assay /// 0045920 // negative regulation of exocytosis // inferred from mutant phenotype /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050812 // regulation of acyl-CoA biosynthetic process // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051583 // dopamine uptake involved in synaptic transmission // traceable author statement /// 0051585 // negative regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0051612 // negative regulation of serotonin uptake // inferred from direct assay /// 0051622 // negative regulation of norepinephrine uptake // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060732 // positive regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0070495 // negative regulation of thrombin receptor signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043205 // fibril // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from direct assay /// 0060961 // phospholipase D inhibitor activity // inferred from direct assay 211547_s_at L13387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L13387.1 /DEF=Homo sapiens (clone 6-1) Miller-Dieker lissencephaly protein (LIS1) mRNA, complete cds. /FEA=mRNA /GEN=LIS1 /PROD=Miller-Dieker lissencephaly protein /DB_XREF=gi:349827 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13387.1 L13387 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 211548_s_at J05594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J05594.1 /DEF=Homo sapiens NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (PDGH) mRNA, complete cds. /FEA=mRNA /GEN=PGDH /PROD=NAD+-dependent 15-hydroxyprostaglandindehydrogenase /DB_XREF=gi:1203981 /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:J05594.1 J05594 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 211549_s_at U63296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U63296.1 /DEF=Human 15-hydroxyprostaglandin dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=15-hydroxyprostaglandin dehydrogenase /DB_XREF=gi:2047312 /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:U63296.1 U63296 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 211550_at AF125253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125253.1 /DEF=Homo sapiens truncated epidermal growth factor receptor precursor (EGFR) mRNA, complete cds. /FEA=mRNA /GEN=EGFR /PROD=truncated epidermal growth factor receptorprecursor /DB_XREF=gi:12002211 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:AF125253.1 AF125253 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 211551_at K03193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03193.1 /DEF=Human aberrant (short) epidermal growth factor receptor mRNA, complete cds. /FEA=mRNA /GEN=EGFR /DB_XREF=gi:181984 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:K03193.1 K03193 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 211552_s_at U24267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U24267.1 /DEF=Human pyrroline-5-carboxylate dehydrogenase (P5CDh) mRNA, short form, complete cds. /FEA=mRNA /GEN=P5CDh /PROD=pyrroline-5-carboxylate dehydrogenase /DB_XREF=gi:1353249 /UG=Hs.77448 aldehyde dehydrogenase 4 family, member A1 /FL=gb:U24267.1 U24267 aldehyde dehydrogenase 4 family, member A1 ALDH4A1 8659 NM_001161504 /// NM_003748 /// NM_170726 0006560 // proline metabolic process // traceable author statement /// 0006561 // proline biosynthetic process // inferred from electronic annotation /// 0006562 // proline catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003842 // 1-pyrroline-5-carboxylate dehydrogenase activity // not recorded /// 0004029 // aldehyde dehydrogenase (NAD) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211553_x_at AF248734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF248734.1 /DEF=Homo sapiens apoptotic protease activating factor 1 variant, mRNA, complete cds. /FEA=mRNA /PROD=apoptotic protease activating factor 1 variant /DB_XREF=gi:13506924 /UG=Hs.77579 apoptotic protease activating factor /FL=gb:AF248734.1 gb:AF149794.1 AF248734 apoptotic peptidase activating factor 1 APAF1 317 NM_001160 /// NM_013229 /// NM_181861 /// NM_181868 /// NM_181869 /// XR_429095 0001843 // neural tube closure // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from direct assay /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0072432 // response to G1 DNA damage checkpoint signaling // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay /// 0043293 // apoptosome // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation 211554_s_at AF149794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF149794.1 /DEF=Homo sapiens apoptotic protease activating factor 1 (APAF1) mRNA, complete cds. /FEA=CDS /GEN=APAF1 /PROD=apoptotic protease activating factor 1 /DB_XREF=gi:4929486 /UG=Hs.77579 apoptotic protease activating factor /FL=gb:AF248734.1 gb:AF149794.1 AF149794 apoptotic peptidase activating factor 1 APAF1 317 NM_001160 /// NM_013229 /// NM_181861 /// NM_181868 /// NM_181869 /// XR_429095 0001843 // neural tube closure // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from direct assay /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0072432 // response to G1 DNA damage checkpoint signaling // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay /// 0043293 // apoptosome // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation 211555_s_at AF020340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF020340.1 /DEF=Homo sapiens soluble guanylate cyclase beta-1 subunit (GC-S-beta-1) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=GC-S-beta-1 /PROD=soluble guanylate cyclase beta-1 subunit /DB_XREF=gi:2746082 /UG=Hs.77890 guanylate cyclase 1, soluble, beta 3 /FL=gb:AF020340.1 AF020340 guanylate cyclase 1, soluble, beta 3 GUCY1B3 2983 NM_000857 /// NM_001291951 /// NM_001291952 /// NM_001291953 /// NM_001291954 /// NM_001291955 /// XM_005262959 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0008074 // guanylate cyclase complex, soluble // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0043167 // ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from electronic annotation 211556_at AB016823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016823.1 /DEF=Homo sapiens mRNA for APC-binding protein EB1, complete cds. /FEA=mRNA /PROD=APC-binding protein EB1 /DB_XREF=gi:5734598 /UG=Hs.78335 microtubule-associated protein, RPEB family, member 2 /FL=gb:AB016823.1 AB016823 microtubule-associated protein, RP/EB family, member 2 MAPRE2 10982 NM_001143826 /// NM_001143827 /// NM_001256420 /// NM_014268 /// NR_046177 /// XM_006722375 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 211557_x_at AF205073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF205073.1 /DEF=Homo sapiens organic anion transporter polypeptide-related protein 2 (OATPRP2) mRNA, complete cds. /FEA=mRNA /GEN=OATPRP2 /PROD=organic anion transporter polypeptide-relatedprotein 2 /DB_XREF=gi:11990588 /UG=Hs.7884 solute carrier family 21 (organic anion transporter), member 9 /FL=gb:AF205073.1 AF205073 solute carrier organic anion transporter family, member 2B1 SLCO2B1 11309 NM_001145211 /// NM_001145212 /// NM_007256 /// XM_006718427 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071718 // sodium-independent icosanoid transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay 211558_s_at U26266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U26266.1 /DEF=Human deoxyhypusine synthase mRNA, complete cds. /FEA=mRNA /PROD=deoxyhypusine synthase /DB_XREF=gi:1373016 /UG=Hs.79064 deoxyhypusine synthase /FL=gb:U26266.1 gb:NM_013406.1 U26266 deoxyhypusine synthase DHPS 1725 NM_001206974 /// NM_001930 /// NM_013406 /// NM_013407 /// NR_038192 0006412 // translation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050983 // deoxyhypusine biosynthetic process from spermidine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0034038 // deoxyhypusine synthase activity // traceable author statement 211559_s_at L49506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L49506.1 /DEF=Homo sapiens cyclin G2 mRNA, complete cds. /FEA=mRNA /PROD=cyclin G2 /DB_XREF=gi:1236234 /UG=Hs.79069 cyclin G2 /FL=gb:L49506.1 L49506 cyclin G2 CCNG2 901 NM_004354 0000075 // cell cycle checkpoint // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 211560_s_at AF130113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130113.1 /DEF=Homo sapiens clone FLB8929 PRO2399 mRNA, complete cds. /FEA=mRNA /PROD=PRO2399 /DB_XREF=gi:11493529 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:AF130113.1 AF130113 aminolevulinate, delta-, synthase 2 ALAS2 212 NM_000032 /// NM_001037967 /// NM_001037968 /// NM_001037969 /// XM_005261995 0001666 // response to hypoxia // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from sequence or structural similarity /// 0006783 // heme biosynthetic process // non-traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006879 // cellular iron ion homeostasis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // non-traceable author statement /// 0032364 // oxygen homeostasis // non-traceable author statement /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003870 // 5-aminolevulinate synthase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016594 // glycine binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from sequence or structural similarity 211561_x_at L35253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L35253.1 /DEF=Human p38 mitogen activated protein (MAP) kinase mRNA, complete cds. /FEA=mRNA /PROD=MAP kinase /DB_XREF=gi:529039 /UG=Hs.79107 mitogen-activated protein kinase 14 /FL=gb:L35253.1 L35253 mitogen-activated protein kinase 14 MAPK14 1432 NM_001315 /// NM_139012 /// NM_139013 /// NM_139014 /// XM_006714998 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038066 // p38MAPK cascade // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090400 // stress-induced premature senescence // inferred from mutant phenotype /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005623 // cell // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity 211562_s_at BC001755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001755.1 /DEF=Homo sapiens, Similar to leiomodin 1 (smooth muscle), clone MGC:1117, mRNA, complete cds. /FEA=mRNA /PROD=Similar to leiomodin 1 (smooth muscle) /DB_XREF=gi:12804660 /UG=Hs.79386 leiomodin 1 (smooth muscle) /FL=gb:BC001755.1 BC001755 leiomodin 1 (smooth muscle) LMOD1 25802 NM_012134 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 211563_s_at AB006572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB006572.1 /DEF=Homo sapiens RMP mRNA for RPB5 meidating protein, complete cds. /FEA=mRNA /GEN=RMP /PROD=RPB5 meidating protein /DB_XREF=gi:3970832 /UG=Hs.7943 RPB5-mediating protein /FL=gb:AB006572.1 gb:NM_003796.1 AB006572 URI1, prefoldin-like chaperone URI1 8725 NM_001252641 /// NM_003796 /// NM_134447 /// NR_045557 /// XM_005259362 /// XM_005259363 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001558 // regulation of cell growth // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0009615 // response to virus // inferred from mutant phenotype /// 0010923 // negative regulation of phosphatase activity // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016272 // prefoldin complex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 211564_s_at BC003096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003096.1 /DEF=Homo sapiens, Similar to LIM domain protein, clone MGC:1645, mRNA, complete cds. /FEA=mRNA /PROD=Similar to LIM domain protein /DB_XREF=gi:13111856 /UG=Hs.79691 LIM domain protein /FL=gb:BC003096.1 BC003096 PDZ and LIM domain 4 PDLIM4 8572 NM_001131027 /// NM_003687 /// XM_006714723 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211565_at AF036272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF036272.1 /DEF=Homo sapiens EEN-B2-L4 mRNA, complete cds. /FEA=mRNA /GEN=EEN-B2-L4 /PROD=EEN-B2-L4 /DB_XREF=gi:2921415 /UG=Hs.80315 SH3-domain GRB2-like 3 /FL=gb:AF036272.1 AF036272 SH3-domain GRB2-like 3 SH3GL3 6457 NM_003027 /// NR_026799 /// XM_006720638 /// XM_006720639 /// XM_006720640 /// XR_429469 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 211566_x_at U19178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19178.1 /DEF=Human (Hin-3)HIV1 promoter region chimeric mRNA, complete cds. /FEA=mRNA /GEN=Hin-3 /DB_XREF=gi:726035 /UG=Hs.80426 brain and reproductive organ-expressed (TNFRSF1A modulator) /FL=gb:U19178.1 U19178 brain and reproductive organ-expressed (TNFRSF1A modulator) BRE 9577 NM_001261840 /// NM_004899 /// NM_199191 /// NM_199192 /// NM_199193 /// NM_199194 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype 0000152 // nuclear ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 211567_at J04168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04168.1 /DEF=Human leukosialin mRNA, complete cds. /FEA=mRNA /GEN=SPN /DB_XREF=gi:187118 /UG=Hs.80738 sialophorin (gpL115, leukosialin, CD43) /FL=gb:J04168.1 J04168 0001562 // response to protozoan // inferred from electronic annotation /// 0001808 // negative regulation of type IV hypersensitivity // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001931 // uropod // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement 211568_at AB011122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB011122.1 /DEF=Homo sapiens mRNA for KIAA0550 protein, complete cds. /FEA=mRNA /GEN=KIAA0550 /PROD=KIAA0550 protein /DB_XREF=gi:3043623 /UG=Hs.8074 brain-specific angiogenesis inhibitor 3 /FL=gb:AB011122.1 AB011122 brain-specific angiogenesis inhibitor 3 BAI3 577 NM_001704 /// XM_005248752 /// XM_005248753 /// XM_006715534 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211569_s_at AF001903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF001903.1 /DEF=Human 3-hydroxyacyl-CoA dehydrogenase, isoform 2 mRNA, complete cds. /FEA=mRNA /PROD=3-hydroxyacyl-CoA dehydrogenase, isoform 2 /DB_XREF=gi:2078328 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:AF001903.1 AF001903 hydroxyacyl-CoA dehydrogenase HADH 3033 NM_001184705 /// NM_005327 /// XM_005262972 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 211570_s_at BC004196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004196.1 /DEF=Homo sapiens, Similar to receptor-associated protein of the synapse, 43kD, clone MGC:3597, mRNA, complete cds. /FEA=mRNA /PROD=Similar to receptor-associated protein of thesynapse, 43kD /DB_XREF=gi:13278866 /UG=Hs.81218 receptor-associated protein of the synapse, 43kD /FL=gb:BC004196.1 BC004196 receptor-associated protein of the synapse RAPSN 5913 NM_005055 /// NM_032645 /// XM_005253042 /// XM_005253043 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from genetic interaction /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from direct assay /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211571_s_at D32039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D32039.1 /DEF=Human pgH3 mRNA for proteoglycan PG-M(V3), complete cds. /FEA=mRNA /GEN=pgH3 /PROD=proteoglycan PG-M(V3) /DB_XREF=gi:1008912 /UG=Hs.81800 chondroitin sulfate proteoglycan 2 (versican) /FL=gb:D32039.1 D32039 versican VCAN 1462 NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385 0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211572_s_at AF092511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF092511.1 /DEF=Homo sapiens nucleobase transporter-like 1 protein (SLC23A1) mRNA, complete cds. /FEA=mRNA /GEN=SLC23A1 /PROD=nucleobase transporter-like 1 protein /DB_XREF=gi:4206717 /UG=Hs.82042 solute carrier family 23 (nucleobase transporters), member 1 /FL=gb:AF092511.1 AF092511 solute carrier family 23 (ascorbic acid transporter), member 2 SLC23A2 9962 NM_005116 /// NM_203327 /// XM_005260904 /// XM_006723671 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0015851 // nucleobase transport // traceable author statement /// 0015882 // L-ascorbic acid transport // inferred from direct assay /// 0015993 // molecular hydrogen transport // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // non-traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0035461 // vitamin transmembrane transport // inferred from direct assay /// 0035461 // vitamin transmembrane transport // inferred from electronic annotation /// 0035461 // vitamin transmembrane transport // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070904 // transepithelial L-ascorbic acid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0008520 // L-ascorbate:sodium symporter activity // inferred from electronic annotation /// 0008523 // sodium-dependent multivitamin transmembrane transporter activity // non-traceable author statement /// 0015205 // nucleobase transmembrane transporter activity // traceable author statement /// 0015229 // L-ascorbic acid transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0070890 // sodium-dependent L-ascorbate transmembrane transporter activity // inferred from direct assay 211573_x_at M98478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M98478.1 /DEF=Human transglutaminase mRNA, complete cds. /FEA=mRNA /PROD=transglutaminase /DB_XREF=gi:339577 /UG=Hs.8265 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:M98478.1 M98478 transglutaminase 2 TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from mutant phenotype /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211574_s_at D84105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D84105.1 /DEF=Human CD46 mRNA, complete cds. /FEA=mRNA /PROD=CD46 /DB_XREF=gi:1256700 /UG=Hs.83532 membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) /FL=gb:D84105.1 D84105 CD46 molecule, complement regulatory protein CD46 4179 NM_002389 /// NM_153826 /// NM_172350 /// NM_172351 /// NM_172352 /// NM_172353 /// NM_172354 /// NM_172355 /// NM_172356 /// NM_172357 /// NM_172358 /// NM_172359 /// NM_172360 /// NM_172361 0002250 // adaptive immune response // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0032613 // interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035581 // sequestering of extracellular ligand from receptor // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from direct assay /// 0045916 // negative regulation of complement activation // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002079 // inner acrosomal membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 211575_s_at AF116702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116702.1 /DEF=Homo sapiens PRO2446 mRNA, complete cds. /FEA=mRNA /PROD=PRO2446 /DB_XREF=gi:7959902 /UG=Hs.83583 actin related protein 23 complex, subunit 2 (34 kD) /FL=gb:AF116702.1 AF116702 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0035037 // sperm entry // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0035650 // AP-1 adaptor complex binding // inferred from electronic annotation /// 0071933 // Arp2/3 complex binding // inferred from electronic annotation 211576_s_at BC003068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003068.1 /DEF=Homo sapiens, Similar to solute carrier family 19 (folate transporter), member 1, clone MGC:2165, mRNA, complete cds. /FEA=mRNA /PROD=Similar to solute carrier family 19 (folatetransporter), member 1 /DB_XREF=gi:13111761 /UG=Hs.84190 solute carrier family 19 (folate transporter), member 1 /FL=gb:BC003068.1 BC003068 uncharacterized LOC101928717 /// solute carrier family 19 (folate transporter), member 1 LOC101928717 /// SLC19A1 6573 /// 101928717 NM_001205206 /// NM_001205207 /// NM_003056 /// NM_194255 /// XM_005261164 /// XR_244332 /// XR_249004 /// XR_254049 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0051958 // methotrexate transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005542 // folic acid binding // inferred from electronic annotation /// 0008517 // folic acid transporter activity // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015350 // methotrexate transporter activity // inferred from electronic annotation 211577_s_at M37484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M37484.1 /DEF=Human insulin-like growth factor I (IGF-I) mRNA, complete cds. /FEA=mRNA /GEN=IGF1 /PROD=insulin-like growth factor I /DB_XREF=gi:184833 /UG=Hs.85112 insulin-like growth factor 1 (somatomedin C) /FL=gb:M37484.1 M37484 insulin-like growth factor 1 (somatomedin C) IGF1 3479 NM_000618 /// NM_001111283 /// NM_001111284 /// NM_001111285 /// XM_005268835 0001501 // skeletal system development // traceable author statement /// 0001775 // cell activation // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009441 // glycolate metabolic process // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from direct assay /// 0014896 // muscle hypertrophy // inferred from mutant phenotype /// 0014904 // myotube cell development // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0021940 // positive regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from direct assay /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from expression pattern /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060426 // lung vasculature development // inferred from electronic annotation /// 0060463 // lung lobe morphogenesis // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060741 // prostate gland stromal morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0031093 // platelet alpha granule lumen // traceable author statement 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 211578_s_at M60725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60725.1 /DEF=Human p70 ribosomal S6 kinase alpha-II mRNA, complete cds. /FEA=mRNA /PROD=p70 ribosomal S6 kinase alpha-II /DB_XREF=gi:189509 /UG=Hs.86858 ribosomal protein S6 kinase, 70kD, polypeptide 1 /FL=gb:M60725.1 M60725 ribosomal protein S6 kinase, 70kDa, polypeptide 1 RPS6KB1 6198 NM_001272042 /// NM_001272043 /// NM_001272044 /// NM_001272060 /// NM_003161 /// XM_006722009 /// XM_006722010 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0014878 // response to electrical stimulus involved in regulation of muscle adaptation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 211579_at U95204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U95204.1 /DEF=Homo sapiens platelet membrane glycoprotein IIIa beta subunit mRNA, complete cds. /FEA=mRNA /PROD=platelet membrane glycoprotein IIIa betasubunit /DB_XREF=gi:2443451 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) /FL=gb:U95204.1 U95204 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 211580_s_at AF028785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF028785.1 /DEF=Homo sapiens phosphatidylinositol 3-kinase p55 gamma regulatory subunit mRNA, complete cds. /FEA=mRNA /PROD=phosphatidylinositol 3-kinase p55 gammaregulatory subunit /DB_XREF=gi:3046405 /UG=Hs.88051 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) /FL=gb:AF028785.1 AF028785 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) PIK3R3 8503 NM_001114172 /// NM_003629 /// XM_005271290 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // traceable author statement /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation 211581_x_at AF000426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000426.1 /DEF=Homo sapiens LST1 mRNA, cLST1E splice variant, complete cds. /FEA=mRNA /GEN=LST1 /DB_XREF=gi:2145067 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF000426.1 AF000426 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 211582_x_at AF000424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF000424.1 /DEF=Homo sapiens LST1 mRNA, cLST1C splice variant, complete cds. /FEA=mRNA /GEN=LST1 /DB_XREF=gi:2145063 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF000424.1 AF000424 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 211583_x_at AF031136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF031136.1 /DEF=Homo sapiens 1C7 precursor, mRNA, alternatively spliced, complete cds. /FEA=mRNA /PROD=1C7 precursor /DB_XREF=gi:2623872 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:AF031136.1 AF031136 natural cytotoxicity triggering receptor 3 NCR3 259197 NM_001145466 /// NM_001145467 /// NM_147130 /// XM_006715049 /// XM_006725031 /// XM_006725478 /// XM_006725692 /// XM_006725808 /// XM_006725902 /// XM_006725903 /// XM_006725989 /// XM_006726081 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0008037 // cell recognition // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211584_s_at U58852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58852.1 /DEF=Human NPAT mRNA, complete cds. /FEA=mRNA /GEN=NPAT /DB_XREF=gi:1381666 /UG=Hs.89385 nuclear protein, ataxia-telangiectasia locus /FL=gb:U58852.1 U58852 nuclear protein, ataxia-telangiectasia locus NPAT 4863 NM_002519 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 211585_at U58852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58852.1 /DEF=Human NPAT mRNA, complete cds. /FEA=mRNA /GEN=NPAT /DB_XREF=gi:1381666 /UG=Hs.89385 nuclear protein, ataxia-telangiectasia locus /FL=gb:U58852.1 U58852 nuclear protein, ataxia-telangiectasia locus NPAT 4863 NM_002519 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 211586_s_at M97260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M97260.1 /DEF=Human plasma membrane Ca2+-ATPase isoform PMCA2a mRNA, complete cds. /FEA=mRNA /PROD=Ca2+-ATPase /DB_XREF=gi:190098 /UG=Hs.89512 ATPase, Ca++ transporting, plasma membrane 2 /FL=gb:M97260.1 M97260 ATPase, Ca++ transporting, plasma membrane 2 ATP2B2 491 NM_001001331 /// NM_001683 /// XM_005265179 /// XM_006713175 /// XM_006713176 /// XM_006713177 /// XM_006713178 /// XM_006713179 /// XM_006713180 /// XM_006713181 /// XM_006713182 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006996 // organelle organization // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021692 // cerebellar Purkinje cell layer morphogenesis // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0040011 // locomotion // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045299 // otolith mineralization // inferred from electronic annotation /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030899 // calcium-dependent ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211587_x_at M37981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M37981.1 /DEF=Human alpha-3 neuronal nicotinic acetylcholine receptor subunit mRNA, complete cds. /FEA=mRNA /GEN=CHRNA3 /PROD=neuronal nicotinic acetylcholine receptor /DB_XREF=gi:189252 /UG=Hs.89605 cholinergic receptor, nicotinic, alpha polypeptide 3 /FL=gb:M37981.1 M37981 cholinergic receptor, nicotinic, alpha 3 (neuronal) CHRNA3 1136 NM_000743 /// NM_001166694 /// NR_046313 /// XM_006720382 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060084 // synaptic transmission involved in micturition // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 211588_s_at AF230401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230401.1 /DEF=Homo sapiens tripartite motif protein TRIM19 alpha mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM19 alpha /DB_XREF=gi:12275890 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230401.1 AF230401 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 211589_at AF230401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230401.1 /DEF=Homo sapiens tripartite motif protein TRIM19 alpha mRNA, complete cds. /FEA=mRNA /PROD=tripartite motif protein TRIM19 alpha /DB_XREF=gi:12275890 /UG=Hs.89633 promyelocytic leukemia /FL=gb:AF230401.1 AF230401 promyelocytic leukemia PML 5371 NM_002675 /// NM_033238 /// NM_033239 /// NM_033240 /// NM_033244 /// NM_033246 /// NM_033247 /// NM_033249 /// NM_033250 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010522 // regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030578 // PML body organization // inferred from direct assay /// 0030578 // PML body organization // inferred from mutant phenotype /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from sequence or structural similarity /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032938 // negative regulation of translation in response to oxidative stress // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045343 // regulation of MHC class I biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 211590_x_at U11271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U11271.1 /DEF=Human alternatively spliced endothelial thromboxane A2 receptor mRNA, complete cds. /FEA=mRNA /PROD=thromboxane A2 receptor /DB_XREF=gi:511793 /UG=Hs.89887 thromboxane A2 receptor /FL=gb:U11271.1 U11271 thromboxane A2 receptor TBXA2R 6915 NM_001060 /// NM_201636 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0038193 // thromboxane A2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004960 // thromboxane receptor activity // inferred from electronic annotation /// 0004961 // thromboxane A2 receptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211591_s_at L20965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20965.1 /DEF=Human phosphodiesterase mRNA, complete cds. /FEA=mRNA /PROD=phosphodiesterase /DB_XREF=gi:347119 /UG=Hs.89901 phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2) /FL=gb:L20965.1 gb:U18087.1 gb:M37744.1 L20965 phosphodiesterase 4A, cAMP-specific PDE4A 5141 NM_001111307 /// NM_001111308 /// NM_001111309 /// NM_001243121 /// NM_006202 /// XM_005259933 /// XM_006722765 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211592_s_at L29536 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L29536.1 /DEF=Human calcium channel L-type alpha 1 subunit (CACNL1A1) mRNA, complete cds. /FEA=mRNA /GEN=CACNL1A1 /PROD=calcium channel L-type alpha 1 subunit /DB_XREF=gi:463081 /UG=Hs.89925 calcium channel, voltage-dependent, L type, alpha 1C subunit /FL=gb:L29536.1 L29536 calcium channel, voltage-dependent, L type, alpha 1C subunit CACNA1C 775 NM_000719 /// NM_001129827 /// NM_001129829 /// NM_001129830 /// NM_001129831 /// NM_001129832 /// NM_001129833 /// NM_001129834 /// NM_001129835 /// NM_001129836 /// NM_001129837 /// NM_001129838 /// NM_001129839 /// NM_001129840 /// NM_001129841 /// NM_001129842 /// NM_001129843 /// NM_001129844 /// NM_001129846 /// NM_001167623 /// NM_001167624 /// NM_001167625 /// NM_199460 /// XM_006719015 /// XM_006719016 /// XM_006719017 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030252 // growth hormone secretion // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035585 // calcium-mediated signaling using extracellular calcium source // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046620 // regulation of organ growth // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // traceable author statement /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement 0002095 // caveolar macromolecular signaling complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0008331 // high voltage-gated calcium channel activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from physical interaction 211593_s_at AB047005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB047005.1 /DEF=Homo sapiens mRNA for MAST205, complete cds. /FEA=mRNA /GEN=hMAST205 /PROD=MAST205 /DB_XREF=gi:13537203 /FL=gb:AB047005.1 AB047005 microtubule associated serine/threonine kinase 2 MAST2 23139 NM_015112 /// XM_005270652 /// XM_005270653 /// XM_005270654 /// XM_005270655 /// XM_005270656 /// XM_005270659 /// XM_006710475 /// XM_006710476 /// XM_006710477 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045075 // regulation of interleukin-12 biosynthetic process // inferred from sequence or structural similarity /// 0048515 // spermatid differentiation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211594_s_at AB049636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049636.1 /DEF=Homo sapiens MRPL9 mRNA for mitochondrial ribosomal protein L9 (L9mt), complete cds. /FEA=mRNA /GEN=MRPL9 /PROD=mitochondrial ribosomal protein L9 (L9mt) /DB_XREF=gi:13559362 /FL=gb:AB049636.1 AB049636 mitochondrial ribosomal protein L9 MRPL9 65005 NM_031420 /// XM_005245455 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211595_s_at AB049944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049944.1 /DEF=Homo sapiens MRPS11 mRNA for mitochondrial ribosomal protein S11, complete cds. /FEA=mRNA /GEN=MRPS11 /PROD=mitochondrial ribosomal protein S11 /DB_XREF=gi:13620888 /FL=gb:AB049944.1 AB049944 mitochondrial ribosomal protein S11 MRPS11 64963 NM_022839 /// NM_176805 /// XM_005254977 /// XM_005254978 0006412 // translation // inferred from electronic annotation /// 0042769 // DNA damage response, detection of DNA damage // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211596_s_at AB050468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB050468.1 /DEF=Homo sapiens mRNA for membrane glycoprotein LIG-1, complete cds. /FEA=mRNA /GEN=lig-1 /PROD=membrane glycoprotein LIG-1 /DB_XREF=gi:13537354 /FL=gb:AB050468.1 AB050468 leucine-rich repeats and immunoglobulin-like domains 1 LRIG1 26018 NM_015541 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211597_s_at AB059408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB059408.1 /DEF=Homo sapiens mRNA, complete cds, clone:SMAP31-12. /FEA=mRNA /DB_XREF=gi:13560280 /FL=gb:AB059408.1 AB059408 HOP homeobox HOPX 84525 NM_001145459 /// NM_001145460 /// NM_032495 /// NM_139211 /// NM_139212 /// XM_005265783 /// XM_006714051 /// XM_006714052 /// XM_006714053 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043415 // positive regulation of skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211598_x_at U18810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18810.1 /DEF=Human PACAP type-3VIP type-2 receptor mRNA, complete cds. /FEA=mRNA /PROD=PACAP type-3VIP type-2 receptor /DB_XREF=gi:1684934 /FL=gb:U18810.1 U18810 vasoactive intestinal peptide receptor 2 VIPR2 7434 NM_003382 /// XM_005249561 /// XM_006716107 /// XM_006716108 /// XR_242047 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004999 // vasoactive intestinal polypeptide receptor activity // inferred from electronic annotation 211599_x_at U19348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19348.1 /DEF=Human (tpr-met fusion) oncogene mRNA, complete cds. /FEA=mRNA /GEN=tprmet fusion /PROD=tpr-met fusion protein /DB_XREF=gi:625085 /FL=gb:U19348.1 U19348 MET proto-oncogene, receptor tyrosine kinase MET 4233 NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 211600_at U20489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U20489.1 /DEF=Human glomerular epithelial protein 1 (GLEPP1) mRNA, complete cds. /FEA=mRNA /GEN=GLEPP1 /PROD=glomerular epithelial protein 1 /DB_XREF=gi:885925 /FL=gb:U20489.1 U20489 protein tyrosine phosphatase, receptor type, O PTPRO 5800 NM_002848 /// NM_030667 /// NM_030668 /// NM_030669 /// NM_030670 /// NM_030671 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0002548 // monocyte chemotaxis // inferred from mutant phenotype /// 0003093 // regulation of glomerular filtration // inferred from sequence or structural similarity /// 0003105 // negative regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // traceable author statement /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036060 // slit diaphragm assembly // inferred from sequence or structural similarity /// 0036060 // slit diaphragm assembly // non-traceable author statement /// 0042773 // ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090260 // negative regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 211601_at U25433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U25433.1 /DEF=Homo sapiens CATR1.3 sequence associated with tumorigenic conversion mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:2959553 /FL=gb:U25433.1 U25433 CATR tumorigenicity conversion 1 CATR1 856 211602_s_at U31110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31110.1 /DEF=Human alternatively spliced trp-1 protein and unspliced trp-1 protein (trp-1) mRNA, complete cds. /FEA=mRNA /GEN=trp-1; trp-1 /PROD=alternatively spliced trp-1 protein; unspliced trp-1 protein /DB_XREF=gi:1072042 /FL=gb:U31110.1 U31110 transient receptor potential cation channel, subfamily C, member 1 TRPC1 7220 NM_001251845 /// NM_003304 /// XM_005247738 /// XM_005247739 /// XM_005247740 /// XR_241506 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0046541 // saliva secretion // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // not recorded /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 211603_s_at U35622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U35622.2 /DEF=Homo sapiens EWS proteinE1A enhancer binding protein chimera mRNA, complete cds. /FEA=mRNA /PROD=EWS proteinE1A enhancer binding proteinchimera /DB_XREF=gi:5733846 /FL=gb:U35622.2 U35622 ets variant 4 ETV4 2118 NM_001079675 /// NM_001261437 /// NM_001261438 /// NM_001261439 /// NM_001986 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211604_x_at U38371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U38371.1 /DEF=Human HAP1-like protein (hHLP1) mRNA, complete cds. /FEA=mRNA /GEN=hHLP1 /PROD=HAP1-like protein /DB_XREF=gi:1103846 /FL=gb:U38371.1 U38371 huntingtin-associated protein 1 HAP1 9001 NM_001079870 /// NM_001079871 /// NM_003949 /// NM_177977 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // non-traceable author statement /// 0008104 // protein localization // inferred from mutant phenotype /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211605_s_at U41742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U41742.1 /DEF=Human nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form mRNA, complete cds. /FEA=mRNA /PROD=nucleophosmin-retinoic acid receptor alphafusion protein NPM-RAR long form /DB_XREF=gi:1314307 /FL=gb:U41742.1 U41742 retinoic acid receptor, alpha RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000415 // negative regulation of histone H3-K36 methylation // inferred from mutant phenotype /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0042255 // ribosome assembly // traceable author statement /// 0042476 // odontogenesis // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0065001 // specification of axis polarity // inferred from mutant phenotype /// 0070171 // negative regulation of tooth mineralization // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0009986 // cell surface // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 211606_at U43279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U43279.1 /DEF=Human nucleoporin nup 36 mRNA, complete cds. /FEA=mRNA /PROD=nup 36 /DB_XREF=gi:1565299 /FL=gb:U43279.1 U43279 211607_x_at U48722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U48722.1 /DEF=Human epidermal growth factor receptor precursor (EGFR) mRNA, complete cds. /FEA=mRNA /PROD=epidermal growth factor receptor precursor /DB_XREF=gi:1628549 /FL=gb:U48722.1 U48722 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 211608_at U50073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U50073.1 /DEF=Human T cell receptor beta chain precursor (Vbeta 12.3) mRNA, complete cds. /FEA=mRNA /GEN=Vbeta 12.3 /PROD=T cell receptor beta chain precursor /DB_XREF=gi:1245340 /FL=gb:U50073.1 U50073 SubName: Full=V_segment translation product; Flags: Fragment; TCRBV12S3 211609_x_at U51007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U51007.1 /DEF=Human 26S protease subunit S5a mRNA, complete cds. /FEA=mRNA /PROD=26S protease subunit S5a /DB_XREF=gi:1256400 /FL=gb:U51007.1 U51007 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 PSMD4 5710 NM_002810 /// NM_153822 /// XM_005245354 /// XM_006711464 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211610_at U51869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U51869.1 /DEF=Human proto-oncogene Bcd orf1 and orf2 mRNA, complete cds. /FEA=mRNA /PROD=Bcd orf2; Bcd orf1 /DB_XREF=gi:2745959 /FL=gb:U51869.1 U51869 Kruppel-like factor 6 KLF6 1316 NM_001008490 /// NM_001160124 /// NM_001160125 /// NM_001300 /// NR_027653 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211611_s_at U52696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U52696.1 /DEF=Human adrenal Creb-rp homolog (Creb-rp), complete cds, and tenascin-X (XB), partial cds, mRNA. /FEA=mRNA /GEN=XB; Creb-rp /PROD=tenascin-X; adrenal Creb-rp homolog /DB_XREF=gi:1703481 /FL=gb:U52696.1 U52696 activating transcription factor 6 beta /// tenascin XB ATF6B /// TNXB 1388 /// 7148 NM_001136153 /// NM_004381 /// NM_019105 /// NM_032470 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211612_s_at U62858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62858.1 /DEF=Human interleukin-13 receptor mRNA, complete cds. /FEA=mRNA /PROD=interleukin-13 receptor /DB_XREF=gi:1695875 /FL=gb:U62858.1 U62858 interleukin 13 receptor, alpha 1 IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 211613_s_at U79250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U79250.1 /DEF=Human glycerol-3-phosphate dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=glycerol-3-phosphate dehydrogenase /DB_XREF=gi:1806627 /FL=gb:U79250.1 U79250 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) GPD2 2820 NM_000408 /// NM_001083112 /// XM_005246469 /// XM_005246470 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0009331 // glycerol-3-phosphate dehydrogenase complex // inferred from electronic annotation 0004368 // glycerol-3-phosphate dehydrogenase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052590 // sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity // inferred from electronic annotation /// 0052591 // sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity // inferred from electronic annotation 211614_at U88898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88898.1 /DEF=Human endogenous retroviral H proteaseintegrase-derived ORF1 mRNA, complete cds, and putative envelope protein mRNA, partial cds. /FEA=mRNA /PROD=putative envelope protein /DB_XREF=gi:2104918 /FL=gb:U88898.1 U88898 endogenous retrovirus group H, member 6 ERVH-6 51581 0006508 // proteolysis // inferred from electronic annotation 0019031 // viral envelope // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation 211615_s_at M92439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M92439.1 /DEF=Human leucine-rich protein mRNA, complete cds. /FEA=mRNA /PROD=leucine-rich protein; leucine-rich protein /DB_XREF=gi:177109 /FL=gb:M92439.1 M92439 leucine-rich pentatricopeptide repeat containing LRPPRC 10128 NM_133259 /// XM_006711915 /// XM_006711916 0000961 // negative regulation of mitochondrial RNA catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0070129 // regulation of mitochondrial translation // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 211616_s_at M86841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M86841.1 /DEF=Human serotonin receptor type 2 (5HT2) mRNA, complete cds. /FEA=mRNA /GEN=5HT2 /PROD=serotonin receptor /DB_XREF=gi:177775 /FL=gb:M86841.1 M86841 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled HTR2A 3356 NM_000621 /// NM_001165947 0001659 // temperature homeostasis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007208 // phospholipase C-activating serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from electronic annotation /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046883 // regulation of hormone secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0070852 // cell body fiber // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051378 // serotonin binding // inferred from direct assay /// 0071886 // 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding // inferred from direct assay 211617_at M21191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21191.1 /DEF=Human aldolase pseudogene mRNA, complete cds. /FEA=mRNA /GEN=ALDOAP2 /DB_XREF=gi:178405 /FL=gb:M21191.1 M21191 aldolase A, fructose-bisphosphate pseudogene 2 ALDOAP2 228 211618_s_at M31008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M31008.1 /DEF=Human intestinal alkaline phosphatase mRNA, complete cds. /FEA=mRNA /GEN=ALPI /DB_XREF=gi:178443 /FL=gb:M31008.1 M31008 alkaline phosphatase, intestinal ALPI 248 NM_001631 /// XR_241303 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0002020 // protease binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // inferred from sequence or structural similarity /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211619_s_at M13077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M13077.1 /DEF=Human placental alkaline phosphatase mRNA, complete cds,. /FEA=mRNA /GEN=ALPP /PROD=alkaline phosphatase precursor /DB_XREF=gi:178471 /FL=gb:M13077.1 M13077 alkaline phosphatase, placental /// alkaline phosphatase, placental-like 2 ALPP /// ALPPL2 250 /// 251 NM_001632 /// NM_031313 /// XM_005246439 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // inferred from direct assay /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211620_x_at L21756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L21756.1 /DEF=Homo sapiens acute myeloid leukemia associated protein (AML1EAP) mRNA, complete cds. /FEA=mRNA /GEN=AML1EAP /DB_XREF=gi:400340 /FL=gb:L21756.1 L21756 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 211621_at M73069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M73069.1 /DEF=Human androgen receptor mutant gene, mRNA, complete cds. /FEA=mRNA /GEN=AR /PROD=androgen receptor /DB_XREF=gi:178655 /FL=gb:M73069.1 M73069 androgen receptor AR 367 NM_000044 /// NM_001011645 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003073 // regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007548 // sex differentiation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0019102 // male somatic sex determination // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045720 // negative regulation of integrin biosynthetic process // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048638 // regulation of developmental growth // inferred from electronic annotation /// 0048645 // organ formation // inferred from electronic annotation /// 0048808 // male genitalia morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060520 // activation of prostate induction by androgen receptor signaling pathway // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0060599 // lateral sprouting involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060685 // regulation of prostatic bud formation // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0060748 // tertiary branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004882 // androgen receptor activity // inferred from direct assay /// 0004882 // androgen receptor activity // inferred from mutant phenotype /// 0004882 // androgen receptor activity // non-traceable author statement /// 0004882 // androgen receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005496 // steroid binding // inferred from electronic annotation /// 0005497 // androgen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // non-traceable author statement /// 0050681 // androgen receptor binding // inferred from electronic annotation /// 0070974 // POU domain binding // inferred from electronic annotation 211622_s_at M33384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33384.1 /DEF=Human ADP-ribosylation factor (ARF3) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:178980 /FL=gb:M33384.1 M33384 ADP-ribosylation factor 3 ARF3 377 NM_001659 /// XM_005268856 /// XM_006719391 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 211623_s_at M30448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30448.1 /DEF=Human casein kinase II beta subunit mRNA, complete cds. /FEA=mRNA /GEN=CSNK2B /DB_XREF=gi:181154 /FL=gb:M30448.1 M30448 fibrillarin FBL 2091 NM_001436 /// XM_005258651 0000278 // mitotic cell cycle // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016074 // snoRNA metabolic process // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from mutant phenotype /// 0033211 // adiponectin-activated signaling pathway // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043623 // cellular protein complex assembly // non-traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // non-traceable author statement /// 0051101 // regulation of DNA binding // non-traceable author statement /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype /// 1990258 // histone glutamine methylation // inferred from direct assay 0001652 // granular component // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005956 // protein kinase CK2 complex // inferred from electronic annotation /// 0005956 // protein kinase CK2 complex // non-traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0031515 // tRNA (m1A) methyltransferase complex // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016429 // tRNA (adenine-N1-)-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019887 // protein kinase regulator activity // inferred from electronic annotation /// 0019887 // protein kinase regulator activity // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 1990259 // histone-glutamine methyltransferase activity // inferred from direct assay 211624_s_at M30625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M30625.1 /DEF=Human dopamine D2 receptor, mRNA, complete cds. /FEA=mRNA /GEN=DRD2 /PROD=dopamine D2 receptor; unknown protein /DB_XREF=gi:181431 /FL=gb:M30625.1 M30625 dopamine receptor D2 DRD2 1813 NM_000795 /// NM_016574 /// XM_005271425 /// XM_006718774 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from sequence or structural similarity /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014854 // response to inactivity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0021984 // adenohypophysis development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0034776 // response to histamine // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from sequence or structural similarity /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046717 // acid secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from sequence or structural similarity /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060124 // positive regulation of growth hormone secretion // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from genetic interaction /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation /// 1900273 // positive regulation of long-term synaptic potentiation // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0035240 // dopamine binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211625_s_at L20469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20469.1 /DEF=Human truncated dopamine D3 receptor mRNA, complete cds. /FEA=mRNA /PROD=dopamine D3 receptor /DB_XREF=gi:306688 /FL=gb:L20469.1 L20469 dopamine receptor D3 DRD3 1814 NM_000796 /// NM_001282563 /// NM_001290809 /// NM_033658 /// NM_033659 /// NM_033660 /// NM_033663 /// XM_005247171 /// XM_006713522 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002016 // regulation of blood volume by renin-angiotensin // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007611 // learning or memory // non-traceable author statement /// 0007612 // learning // non-traceable author statement /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0032416 // negative regulation of sodium:proton antiporter activity // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034776 // response to histamine // inferred from direct assay /// 0035176 // social behavior // non-traceable author statement /// 0035483 // gastric emptying // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from expression pattern /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046717 // acid secretion // inferred from sequence or structural similarity /// 0048148 // behavioral response to cocaine // inferred from expression pattern /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from sequence or structural similarity /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from mutant phenotype /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0035240 // dopamine binding // inferred from electronic annotation 211626_x_at M21535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M21535.1 /DEF=Human erg protein (ets-related gene) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:182182 /FL=gb:M21535.1 M21535 v-ets avian erythroblastosis virus E26 oncogene homolog ERG 2078 NM_001136154 /// NM_001136155 /// NM_001243428 /// NM_001243429 /// NM_001243432 /// NM_001243433 /// NM_001291391 /// NM_004449 /// NM_182918 /// NR_111949 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211627_x_at M69297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M69297.1 /DEF=Human estrogen receptor-related protein (variant ER from breast cancer) mRNA, complete cds. /FEA=mRNA /GEN=estrogen receptor-related protein /DB_XREF=gi:182218 /FL=gb:M69297.1 M69297 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211628_x_at J04755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:J04755.1 /DEF=Human ferritin H processed pseudogene, complete cds. /FEA=mRNA /GEN=FTHP1 /DB_XREF=gi:182512 /FL=gb:J04755.1 J04755 ferritin, heavy polypeptide 1 pseudogene 5 FTH1P5 2509 211630_s_at L42531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L42531.1 /DEF=Homo sapiens (clone pGSH1) glutathione synthetase (gsh-s) mRNA, complete cds. /FEA=mRNA /GEN=gsh-s /PROD=glutathione synthetase /DB_XREF=gi:886283 /FL=gb:L42531.1 L42531 glutathione synthetase GSS 2937 NM_000178 /// XM_005260406 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004363 // glutathione synthase activity // traceable author statement /// 0005524 // ATP binding // inferred from direct assay /// 0016594 // glycine binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211631_x_at M22921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M22921.1 /DEF=Human beta 1,4-galactosyl-transferase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183670 /FL=gb:M22921.1 M22921 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction 211632_at L34163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34163.1 /DEF=Human Ig rearranged gamma-3 chain gene VH4-Dm1Dxp1-JH3 region, complete cds., polyreactive. /FEA=mRNA /DB_XREF=gi:576593 /FL=gb:L34163.1 L34163 immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHD /// IGHG1 /// IGHM 3495 /// 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211633_x_at M24668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24668.1 /DEF=Human Ig rearranged H-chain V-region mRNA (C-D-JH4), complete cds. /FEA=mRNA /GEN=IGH@ /DB_XREF=gi:185198 /FL=gb:M24668.1 M24668 211634_x_at M24669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24669.1 /DEF=Human Ig rearranged H-chain V-region mRNA (C-D-JH6), complete cds. /FEA=mRNA /GEN=IGH@ /DB_XREF=gi:185200 /FL=gb:M24669.1 M24669 immunoglobulin heavy constant mu IGHM 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211635_x_at M24670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M24670.1 /DEF=Human Ig rearranged H-chain V-region mRNA (C-D-JH6), complete cds. /FEA=mRNA /GEN=IGH@ /DB_XREF=gi:185202 /FL=gb:M24670.1 M24670 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHG4 /// IGHM /// IGHV4-31 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3503 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211636_at L23515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23515.1 /DEF=Human Ig rearranged gamma-chain, V-DXP4-JH4b, complete cds. /FEA=mRNA /DB_XREF=gi:385217 /FL=gb:L23515.1 L23515 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 /// putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like IGHA1 /// IGHA2 /// IGHG1 /// IGHG4 /// IGHM /// IGHV4-31 /// LOC102723407 3493 /// 3494 /// 3500 /// 3503 /// 3507 /// 28396 /// 102723407 XM_006724899 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211637_x_at L23516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23516.1 /DEF=Human Ig rearranged gamma-chain, V-DXP4-JH6c, complete cds. /FEA=mRNA /DB_XREF=gi:385218 /FL=gb:L23516.1 L23516 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 3-23 /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHG4 /// IGHM /// IGHV3-23 /// IGHV4-31 3492 /// 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3503 /// 3507 /// 28396 /// 28442 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211638_at L23517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23517.1 /DEF=Human Ig rearranged gamma-chain, V-DK4-JH3, complete cds. /FEA=mRNA /DB_XREF=gi:385219 /FL=gb:L23517.1 L23517 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHM /// IGHV4-31 3492 /// 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3507 /// 28396 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211639_x_at L23518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23518.1 /DEF=Human Ig rearranged gamma-chain, V-DXP1-JH4b, complete cds. /FEA=mRNA /DB_XREF=gi:385220 /FL=gb:L23518.1 L23518 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHG4 /// IGHM /// IGHV4-31 3492 /// 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3503 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211640_x_at L23519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L23519.1 /DEF=Human Ig rearranged gamma-chain, V-DK4-JH4b, complete cds. /FEA=mRNA /DB_XREF=gi:388020 /FL=gb:L23519.1 L23519 immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHG1 /// IGHM 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211641_x_at L06101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L06101.1 /DEF=Human IG VH-region gene, complete cds. /FEA=mRNA /GEN=IGH@ /PROD=immunoglobulin heavy chain V-region /DB_XREF=gi:185526 /FL=gb:L06101.1 L06101 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHM /// IGHV4-31 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211642_at L06102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L06102.1 /DEF=Human IG processed VH-region mRNA, complete cds. /FEA=mRNA /GEN=IGH@ /PROD=immunoglobulin heavy chain V region /DB_XREF=gi:185528 /FL=gb:L06102.1 L06102 immunoglobulin heavy variable 3-73 /// IGHV3-73 /// IGHV3-73 0005515 // protein binding // inferred from electronic annotation 211643_x_at L14457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14457.1 /DEF=Human Ig rearranged kappa-chain gene V-J-region, complete cds. /FEA=mRNA /DB_XREF=gi:398491 /FL=gb:L14457.1 L14457 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211644_x_at L14458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14458.1 /DEF=Human Ig rearranged kappa-chain gene V-J-region, complete cds. /FEA=mRNA /DB_XREF=gi:398492 /FL=gb:L14458.1 L14458 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211645_x_at M85256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M85256.1 /DEF=Homo sapiens immunoglobulin kappa-chain VK-1 (IgK) mRNA, complete cds. /FEA=mRNA /GEN=IgK /PROD=immunoglobulin kappa-chain VK-1 /DB_XREF=gi:186008 /FL=gb:M85256.1 M85256 immunoglobulin kappa variable 1-17 /// IGKV1-17 /// IGKV1-17 0005515 // protein binding // inferred from electronic annotation 211646_at L14453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14453.1 /DEF=Human Ig rearranged mu-chain gene V-N-D-N-J-region, complete cds. /FEA=mRNA /DB_XREF=gi:398494 /FL=gb:L14453.1 L14453 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// uncharacterized LOC102725526 IGH /// IGHA1 /// IGHG1 /// IGHG2 /// IGHG3 /// IGHM /// LOC102725526 3492 /// 3493 /// 3500 /// 3501 /// 3502 /// 3507 /// 102725526 XR_425424 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211647_x_at L14454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14454.1 /DEF=Human Ig rearranged mu-chain gene V-N-D-N-J-region, complete cds. /FEA=mRNA /DB_XREF=gi:398495 /FL=gb:L14454.1 L14454 immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHG1 /// IGHM 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211648_at L14455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14455.1 /DEF=Human Ig rearranged mu-chain gene V-N-D-N-J-reion, complete cds. /FEA=mRNA /DB_XREF=gi:398496 /FL=gb:L14455.1 L14455 immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHG1 /// IGHM 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211649_x_at L14456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L14456.1 /DEF=Human Ig rearranged mu-chain gene V-N-D-N-J-region, complete cds. /FEA=mRNA /DB_XREF=gi:398497 /FL=gb:L14456.1 L14456 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHA1 /// IGHG1 /// IGHM 3493 /// 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211650_x_at L34164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34164.1 /DEF=Human Ig rearranged mu-chain gene VH3-D2110-JH2, complete cds., polyreactive. /FEA=mRNA /DB_XREF=gi:576594 /FL=gb:L34164.1 L34164 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 3-23 /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHD /// IGHG1 /// IGHG3 /// IGHM /// IGHV3-23 /// IGHV4-31 3492 /// 3493 /// 3495 /// 3500 /// 3502 /// 3507 /// 28396 /// 28442 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211651_s_at M20206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M20206.1 /DEF=Human laminin B1 mRNA, complete cds. /FEA=mRNA /GEN=LAMB1 /DB_XREF=gi:186914 /FL=gb:M20206.1 M20206 laminin, beta 1 LAMB1 3912 NM_002291 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021812 // neuronal-glial interaction involved in cerebral cortex radial glia guided migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042476 // odontogenesis // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from direct assay /// 0005606 // laminin-1 complex // inferred from physical interaction /// 0005606 // laminin-1 complex // traceable author statement /// 0005607 // laminin-2 complex // inferred from direct assay /// 0005607 // laminin-2 complex // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043256 // laminin complex // inferred from electronic annotation /// 0043257 // laminin-8 complex // inferred from direct assay /// 0043257 // laminin-8 complex // traceable author statement /// 0043259 // laminin-10 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 211652_s_at M35533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M35533.1 /DEF=Human lipopolysaccharide binding protein (LBP) mRNA, complete cds. /FEA=mRNA /GEN=LBP /DB_XREF=gi:186965 /FL=gb:M35533.1 M35533 lipopolysaccharide binding protein LBP 3929 NM_004139 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002232 // leukocyte chemotaxis involved in inflammatory response // inferred from electronic annotation /// 0002281 // macrophage activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from expression pattern /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0008228 // opsonization // inferred by curator /// 0008228 // opsonization // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032490 // detection of molecule of bacterial origin // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // inferred by curator /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0060265 // positive regulation of respiratory burst involved in inflammatory response // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001530 // lipopolysaccharide binding // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0070891 // lipoteichoic acid binding // inferred from direct assay 211653_x_at M33376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M33376.1 /DEF=Human pseudo-chlordecone reductase mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:187444 /FL=gb:M33376.1 M33376 aldo-keto reductase family 1, member C2 /// aldo-keto reductase family 1 member C2-like AKR1C2 /// LOC101930400 1646 /// 101930400 NM_001135241 /// NM_001354 /// NM_205845 /// XM_005276094 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation 211654_x_at M17565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M17565.1 /DEF=Human MHC class II DQ-beta associated with DRw6, DQw1 protein, complete cds. /FEA=mRNA /GEN=HLA-DQB1 /DB_XREF=gi:188188 /FL=gb:M17565.1 M17565 major histocompatibility complex, class II, DQ beta 1 HLA-DQB1 3119 NM_001243961 /// NM_001243962 /// NM_002123 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 211655_at D01059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D01059.1 /DEF=Homo sapiens mRNA for immunoglobulin lambda light chain, complete cds. /FEA=mRNA /GEN=YM-1 /PROD=immunoglobulin lambda light chain /DB_XREF=gi:219887 /UG=Hs.181125 immunoglobulin lambda locus /FL=gb:D01059.1 D01059 immunoglobulin lambda constant 1 (Mcg marker) IGLC1 3537 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 211656_x_at M32577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M32577.1 /DEF=Human MHC HLA-DQ beta mRNA, complete cds. /FEA=mRNA /GEN=HLA-DQB1 /DB_XREF=gi:188194 /FL=gb:M32577.1 M32577 major histocompatibility complex, class II, DQ beta 1 /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// LOC101060835 3119 /// 101060835 NM_001243961 /// NM_001243962 /// NM_002123 /// XM_003960955 /// XM_005276082 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 211657_at M18728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M18728.1 /DEF=Human nonspecific crossreacting antigen mRNA, complete cds. /FEA=mRNA /GEN=NCA; NCA; NCA /PROD=non-specific cross reacting antigen /DB_XREF=gi:189084 /FL=gb:M18728.1 M18728 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) CEACAM6 4680 NM_002483 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211658_at L19185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L19185.1 /DEF=Human natural killer cell enhancing factor (NKEFB) mRNA, complete cds. /FEA=mRNA /GEN=NKEFB /PROD=enhancer protein /DB_XREF=gi:440307 /FL=gb:L19185.1 L19185 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181737 /// NM_181738 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 211659_at M76676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76676.1 /DEF=Homo sapiens leukocyte platelet-activating factor receptor mRNA, complete cds. /FEA=mRNA /PROD=leukocyte platelet-activating factor receptor /DB_XREF=gi:2810988 /FL=gb:M76676.1 M76676 G protein-coupled receptor 135 GPR135 64582 NM_022571 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004992 // platelet activating factor receptor activity // traceable author statement 211660_at M36653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M36653.1 /DEF=Human Oct-2 factor mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:189362 /FL=gb:M36653.1 M36653 POU class 2 homeobox 2 POU2F2 5452 NM_001207025 /// NM_001207026 /// NM_001247994 /// NM_002698 /// XM_005259009 /// XM_005259010 /// XM_005259011 /// XM_005259012 0002335 // mature B cell differentiation // inferred from electronic annotation /// 0002380 // immunoglobulin secretion involved in immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048305 // immunoglobulin secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 211661_x_at M80436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M80436.1 /DEF=Human platelet activating factor receptor mRNA, complete cds. /FEA=mRNA /GEN=PTAFR /PROD=platelet activating factor receptor /DB_XREF=gi:189537 /FL=gb:M80436.1 M80436 platelet-activating factor receptor PTAFR 5724 NM_000952 /// NM_001164721 /// NM_001164722 /// NM_001164723 0001816 // cytokine production // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032959 // inositol trisphosphate biosynthetic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0001875 // lipopolysaccharide receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004992 // platelet activating factor receptor activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay 211662_s_at L08666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L08666.1 /DEF=Homo sapiens porin (por) mRNA, complete cds and truncated cds. /FEA=mRNA /GEN=por; por /PROD=porin; porin /DB_XREF=gi:190199 /FL=gb:L08666.1 L08666 voltage-dependent anion channel 2 VDAC2 7417 NM_001184783 /// NM_001184823 /// NM_003375 /// NR_033675 /// XM_006717961 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0032272 // negative regulation of protein polymerization // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 211663_x_at M61900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M61900.1 /DEF=Human prostaglandin D synthase gene, complete cds. /FEA=mRNA /PROD=prostaglandin D synthase; prostaglandin D synthase /DB_XREF=gi:190443 /FL=gb:M61900.1 M61900 prostaglandin D2 synthase 21kDa (brain) PTGDS 5730 NM_000954 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004667 // prostaglandin-D synthase activity // inferred from direct assay /// 0004667 // prostaglandin-D synthase activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005501 // retinoid binding // inferred from sequence or structural similarity /// 0005504 // fatty acid binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation 211665_s_at L20686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L20686.1 /DEF=Homo sapiens guanine nucleotide releasing factor (SOS2) mRNA, complete cds. /FEA=mRNA /GEN=SOS2 /PROD=guanine nucleotide releasing factor /DB_XREF=gi:1220367 /FL=gb:L20686.1 L20686 son of sevenless homolog 2 (Drosophila) SOS2 6655 NM_006939 /// XM_005268021 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211666_x_at L22453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L22453.1 /DEF=Homo sapiens HIV-1 TAR RNA binding protein (TARBP-b) mRNA, complete cds. /FEA=mRNA /GEN=TARBP-b /DB_XREF=gi:347963 /FL=gb:L22453.1 L22453 RNA, U86 small nucleolar /// ribosomal protein L3 /// small nucleolar RNA, C/D box 83B RNU86 /// RPL3 /// SNORD83B 6122 /// 116936 /// 116938 NM_000967 /// NM_001033853 /// NR_000026 /// NR_000028 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211667_x_at L34698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34698.1 /DEF=Homo sapiens T-cell receptor alpha (TCRA) mRNA (HLA-A3, 29; B7, 44; DR 2, 7), complete cds. /FEA=mRNA /GEN=TCRA /PROD=T-cell receptor alpha /DB_XREF=gi:1100155 /FL=gb:L34698.1 L34698 T cell receptor alpha variable 12-2 TRAV12-2 28673 211668_s_at K03226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:K03226.1 /DEF=Human preprourokinase mRNA, complete cds. /FEA=mRNA /GEN=PLAU /DB_XREF=gi:340155 /FL=gb:K03226.1 K03226 plasminogen activator, urokinase PLAU 5328 NM_001145031 /// NM_002658 /// XM_006717893 0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0061041 // regulation of wound healing // inferred by curator /// 2000097 // regulation of smooth muscle cell-matrix adhesion // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211670_x_at S82471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:S82471.1 /DEF=Homo sapiens Kruppel-associated box containing gene product SSX3 (SSX3) mRNA, complete cds. /FEA=mRNA /GEN=SSX3 /PROD=Kruppel-associated box containing gene productSSX3 /DB_XREF=gi:1699271 /FL=gb:S82471.1 S82471 synovial sarcoma, X breakpoint 3 SSX3 10214 NM_021014 /// NM_175711 /// XM_005272579 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 211671_s_at U01351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U01351.1 /DEF=Human glucocorticoid receptor alpha-2 mRNA, complete cds. /FEA=mRNA /PROD=glucocorticoid receptor alpha-2 /DB_XREF=gi:458656 /FL=gb:U01351.1 U01351 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 211672_s_at AF019888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF019888.1 /DEF=Homo sapiens Arp23 complex 20 kDa subunit (ARC20) mRNA, complete cds. /FEA=mRNA /GEN=ARC20 /PROD=Arp23 complex 20 kDa subunit /DB_XREF=gi:2444286 /FL=gb:AF019888.1 AF019888 actin related protein 2/3 complex, subunit 4, 20kDa /// ARPC4-TTLL3 readthrough ARPC4 /// ARPC4-TTLL3 10093 /// 100526693 NM_001024959 /// NM_001024960 /// NM_001198780 /// NM_001198793 /// NM_005718 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement 211673_s_at AF034374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF034374.1 /DEF=Homo sapiens molybdenum cofactor biosynthesis protein A and molybdenum cofactor biosynthesis protein C mRNA, complete cds. /FEA=mRNA /PROD=molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein A /DB_XREF=gi:2645878 /FL=gb:AF034374.1 AF034374 molybdenum cofactor synthesis 1 MOCS1 4337 NM_001075098 /// NM_005942 /// NM_005943 /// NM_138928 /// NR_033233 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from direct assay /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from mutant phenotype /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019008 // molybdopterin synthase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation /// 0061597 // cyclic pyranopterin monophosphate synthase activity // inferred from electronic annotation /// 0061597 // cyclic pyranopterin monophosphate synthase activity // inferred from mutant phenotype 211674_x_at AF038567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF038567.1 /DEF=Homo sapiens cancer antigen-3 and cancer antigen-3-ORF2 mRNA, complete cds. /FEA=mRNA /PROD=cancer antigen-3-ORF2; cancer antigen-3 /DB_XREF=gi:4104676 /FL=gb:AF038567.1 AF038567 cancer/testis antigen 1A /// cancer/testis antigen 1B CTAG1A /// CTAG1B 1485 /// 246100 NM_001327 /// NM_139250 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211675_s_at AF054589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF054589.1 /DEF=Homo sapiens HIC protein isoform p40 and HIC protein isoform p32 mRNAs, complete cds. /FEA=mRNA /PROD=HIC protein isoform p32; HIC protein isoform p40 /DB_XREF=gi:3426297 /FL=gb:AF054589.1 AF054589 MyoD family inhibitor domain containing MDFIC 29969 NM_001166345 /// NM_001166346 /// NM_199072 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050434 // positive regulation of viral transcription // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0072588 // box H/ACA RNP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from direct assay 211676_s_at AF056979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF056979.1 /DEF=Homo sapiens clone YAN1 interferon-gamma receptor mRNA, complete cds. /FEA=mRNA /PROD=interferon-gamma receptor /DB_XREF=gi:13562048 /FL=gb:AF056979.1 AF056979 interferon gamma receptor 1 IFNGR1 3459 NM_000416 /// XM_006715470 /// XM_006715471 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0004906 // interferon-gamma receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from electronic annotation 211677_x_at AF062733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062733.2 /DEF=Homo sapiens nectin-like protein 1 (NECL1) mRNA, complete cds. /FEA=mRNA /GEN=NECL1 /PROD=nectin-like protein 1 /DB_XREF=gi:13631546 /FL=gb:AF062733.2 AF062733 cell adhesion molecule 3 CADM3 57863 NM_001127173 /// NM_021189 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 211678_s_at AF090934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF090934.1 /DEF=Homo sapiens clone HQ0518 PRO0518 mRNA, complete cds. /FEA=mRNA /PROD=PRO0518 /DB_XREF=gi:6690233 /FL=gb:AF090934.1 AF090934 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032274 // gonadotropin secretion // inferred from expression pattern /// 0032274 // gonadotropin secretion // inferred from mutant phenotype /// 0034337 // RNA folding // inferred from direct assay /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0044029 // hypomethylation of CpG island // inferred from sequence or structural similarity /// 0045746 // negative regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 2000279 // negative regulation of DNA biosynthetic process // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211679_x_at AF095784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF095784.1 /DEF=Homo sapiens GABA-B receptor R2 (GABBR2) mRNA, complete cds. /FEA=mRNA /GEN=GABBR2 /PROD=GABA-B receptor R2 /DB_XREF=gi:4836217 /FL=gb:AF095784.1 AF095784 gamma-aminobutyric acid (GABA) B receptor, 2 GABBR2 9568 NM_005458 /// XM_005252316 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 211680_at AF116705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116705.1 /DEF=Homo sapiens PRO2489 mRNA, complete cds. /FEA=mRNA /PROD=PRO2489 /DB_XREF=gi:7959908 /FL=gb:AF116705.1 AF116705 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211681_s_at AF116705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116705.1 /DEF=Homo sapiens PRO2489 mRNA, complete cds. /FEA=mRNA /PROD=PRO2489 /DB_XREF=gi:7959908 /FL=gb:AF116705.1 AF116705 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211682_x_at AF177272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF177272.1 /DEF=Homo sapiens UDP-glucuronosyltransferase type 1 (UGT2B28) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=UGT2B28 /PROD=UDP-glucuronosyltransferase type 1 /DB_XREF=gi:13603475 /FL=gb:AF177272.1 AF177272 UDP glucuronosyltransferase 2 family, polypeptide B28 UGT2B28 54490 NM_001207004 /// NM_053039 /// XM_005265697 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from direct assay /// 0030259 // lipid glycosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211684_s_at AF250307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF250307.1 /DEF=Homo sapiens cytoplasmic dynein intermediate chain 2C mRNA, complete cds. /FEA=mRNA /PROD=cytoplasmic dynein intermediate chain 2C /DB_XREF=gi:13649464 /FL=gb:AF250307.1 AF250307 dynein, cytoplasmic 1, intermediate chain 2 DYNC1I2 1781 NM_001271785 /// NM_001271786 /// NM_001271787 /// NM_001271788 /// NM_001271789 /// NM_001271790 /// NM_001378 /// XM_005246363 /// XM_005246364 /// XM_005246365 /// XM_005246366 /// XM_005246367 /// XM_005246369 /// XM_006712347 /// XM_006712348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211685_s_at AF251061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF251061.1 /DEF=Homo sapiens neurocalcin mRNA, complete cds. /FEA=mRNA /PROD=neurocalcin /DB_XREF=gi:13625183 /FL=gb:AF251061.1 AF251061 neurocalcin delta NCALD 83988 NM_001040624 /// NM_001040625 /// NM_001040626 /// NM_001040627 /// NM_001040628 /// NM_001040629 /// NM_001040630 /// NM_032041 /// XM_006716672 0003073 // regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211686_s_at AF251062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF251062.1 /DEF=Homo sapiens RNA binding protein mRNA, complete cds. /FEA=mRNA /PROD=RNA binding protein /DB_XREF=gi:13625185 /FL=gb:AF251062.1 AF251062 MAK16 homolog (S. cerevisiae) MAK16 84549 NM_032509 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 211687_x_at AF262973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF262973.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor 3DL1 (KIR3DL1) mRNA, KIR3DL1*00701 allele, complete cds. /FEA=mRNA /GEN=KIR3DL1 /PROD=killer cell immunoglobulin-like receptor 3DL1 /DB_XREF=gi:13560450 /FL=gb:AF262973.1 AF262973 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 KIR3DL1 3811 NM_013289 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 211688_x_at AF263617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF263617.1 /DEF=Homo sapiens killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) mRNA, KIR3DL2*00901 allele, complete cds. /FEA=mRNA /GEN=KIR3DL2 /PROD=killer cell immunoglobulin-like receptor 3DL2 /DB_XREF=gi:13560454 /FL=gb:AF263617.1 AF263617 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 KIR3DL1 /// KIR3DL2 3811 /// 3812 NM_001242867 /// NM_006737 /// NM_013289 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 211689_s_at AF270487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF270487.1 /DEF=Homo sapiens androgen-regulated serine protease TMPRSS2 precursor (TMPRSS2) mRNA, complete cds. /FEA=mRNA /GEN=TMPRSS2 /PROD=androgen-regulated serine protease TMPRSS2precursor /DB_XREF=gi:13540003 /FL=gb:AF270487.1 AF270487 transmembrane protease, serine 2 TMPRSS2 7113 NM_001135099 /// NM_005656 /// XM_005261042 /// XM_005261043 /// XM_005261044 /// XM_006724048 0006508 // proteolysis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from mutant phenotype /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 211690_at AF274945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274945.1 /DEF=Homo sapiens PNAS-20 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-20 /DB_XREF=gi:12751054 /FL=gb:AF274945.1 AF274945 ribosomal protein S6 RPS6 6194 NM_001010 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211691_x_at AF293339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF293339.1 /DEF=Homo sapiens ornithine decarboxylase antizyme 4 mRNA, complete cds. /FEA=mRNA /PROD=ornithine decarboxylase antizyme 4 /DB_XREF=gi:11024341 /FL=gb:AF293339.1 AF293339 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 211692_s_at AF332558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF332558.1 /DEF=Homo sapiens PUMAJFY1 protein mRNA, complete cds. /FEA=mRNA /PROD=PUMAJFY1 protein /DB_XREF=gi:13591689 /FL=gb:AF332558.1 AF332558 BCL2 binding component 3 /// microRNA 3190 /// microRNA 3191 BBC3 /// MIR3190 /// MIR3191 27113 /// 100422832 /// 100422899 NM_001127240 /// NM_001127241 /// NM_001127242 /// NM_014417 /// NR_036158 /// NR_036159 /// XM_005258740 /// XM_006723141 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045926 // negative regulation of growth // inferred from mutant phenotype /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2001056 // positive regulation of cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 211693_at AF343666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF343666.1 /DEF=Homo sapiens translocation associated fusion protein IRTA1IGA1 (IRTA1IGHA1) mRNA, complete cds. /FEA=mRNA /GEN=IRTA1IGHA1 /PROD=translocation associated fusion proteinIRTA1IGA1 /DB_XREF=gi:13591717 /FL=gb:AF343666.1 AF343666 immunoglobulin heavy locus IGH 3492 0001895 // retina homeostasis // inferred from expression pattern /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0003823 // antigen binding // non-traceable author statement /// 0034987 // immunoglobulin receptor binding // inferred from direct assay 211694_at AF348076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348076.1 /DEF=Homo sapiens serinethreonine kinase FKSG81 (FKSG81) mRNA, complete cds. /FEA=mRNA /GEN=FKSG81 /PROD=serinethreonine kinase FKSG81 /DB_XREF=gi:13540323 /FL=gb:AF348076.1 AF348076 testis-specific serine kinase 1B TSSK1B 83942 NM_032028 0006468 // protein phosphorylation // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211695_x_at AF348143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348143.1 /DEF=Homo sapiens mucin short variant (MUC1) mRNA, complete cds. /FEA=mRNA /GEN=MUC1 /PROD=mucin short variant /DB_XREF=gi:13560650 /FL=gb:AF348143.1 AF348143 mucin 1, cell surface associated MUC1 4582 NM_001018016 /// NM_001018017 /// NM_001018021 /// NM_001044390 /// NM_001044391 /// NM_001044392 /// NM_001044393 /// NM_001204285 /// NM_001204286 /// NM_001204287 /// NM_001204288 /// NM_001204289 /// NM_001204290 /// NM_001204291 /// NM_001204292 /// NM_001204293 /// NM_001204294 /// NM_001204295 /// NM_001204296 /// NM_001204297 /// NM_002456 /// NM_182741 0001666 // response to hypoxia // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016266 // O-glycan processing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043618 // regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090240 // positive regulation of histone H4 acetylation // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 211696_x_at AF349114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349114.1 /DEF=Homo sapiens beta globin chain variant (HBB) mRNA, complete cds. /FEA=mRNA /GEN=HBB /PROD=beta globin chain variant /DB_XREF=gi:13549111 /FL=gb:AF349114.1 AF349114 hemoglobin, beta HBB 3043 NM_000518 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211697_x_at AF349314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349314.1 /DEF=Homo sapiens RNA-binding protein LOC56902 mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein LOC56902 /DB_XREF=gi:13540364 /FL=gb:AF349314.1 AF349314 partner of NOB1 homolog (S. cerevisiae) PNO1 56902 NM_020143 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211698_at AF349444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349444.1 /DEF=Homo sapiens Rb- and p300-binding protein EID-1 mRNA, complete cds. /FEA=mRNA /PROD=Rb- and p300-binding protein EID-1 /DB_XREF=gi:13549113 /FL=gb:AF349444.1 AF349444 EP300 interacting inhibitor of differentiation 1 EID1 23741 NM_014335 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from direct assay /// 0035065 // regulation of histone acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0035034 // histone acetyltransferase regulator activity // inferred from direct assay /// 0035035 // histone acetyltransferase binding // inferred from direct assay 211699_x_at AF349571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349571.1 /DEF=Homo sapiens hemoglobin alpha-1 globin chain (HBA1) mRNA, complete cds. /FEA=mRNA /GEN=HBA1 /PROD=hemoglobin alpha-1 globin chain /DB_XREF=gi:13650073 /FL=gb:AF349571.1 AF349571 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211700_s_at AF349719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349719.1 /DEF=Homo sapiens magphinin alpha (TRO) mRNA, complete cds. /FEA=mRNA /GEN=TRO /PROD=magphinin alpha /DB_XREF=gi:13560710 /FL=gb:AF349719.1 AF349719 trophinin TRO 7216 NM_001039705 /// NM_001271183 /// NM_001271184 /// NM_016157 /// NM_177556 /// NM_177557 /// NR_073148 /// NR_073149 /// XM_006724599 /// XM_006724600 /// XM_006724601 /// XM_006724602 /// XM_006724603 /// XM_006724604 /// XM_006724605 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 211701_s_at AF349720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349720.1 /DEF=Homo sapiens magphinin beta (TRO) mRNA, complete cds. /FEA=mRNA /GEN=TRO /PROD=magphinin beta /DB_XREF=gi:13560712 /FL=gb:AF349720.1 AF349720 trophinin TRO 7216 NM_001039705 /// NM_001271183 /// NM_001271184 /// NM_016157 /// NM_177556 /// NM_177557 /// NR_073148 /// NR_073149 /// XM_006724599 /// XM_006724600 /// XM_006724601 /// XM_006724602 /// XM_006724603 /// XM_006724604 /// XM_006724605 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 211702_s_at AF350251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF350251.1 /DEF=Homo sapiens ubiquitin specific protease mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin specific protease /DB_XREF=gi:13560796 /FL=gb:AF350251.1 AF350251 ubiquitin specific peptidase 32 USP32 84669 NM_032582 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211703_s_at AF353990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF353990.1 /DEF=Homo sapiens beta-amyloid binding protein precursor (BBP) mRNA, complete cds. /FEA=mRNA /GEN=BBP /PROD=beta-amyloid binding protein precursor /DB_XREF=gi:13625458 /FL=gb:AF353990.1 AF353990 TM2 domain containing 1 TM2D1 83941 NM_032027 /// XM_005271250 /// XR_246299 0006915 // apoptotic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 211704_s_at AF356353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF356353.1 /DEF=Homo sapiens spindlin-like protein 2 (SPIN2) mRNA, complete cds. /FEA=mRNA /GEN=SPIN2 /PROD=spindlin-like protein 2 /DB_XREF=gi:13650143 /FL=gb:AF356353.1 AF356353 spindlin family, member 2A /// spindlin family, member 2B SPIN2A /// SPIN2B 54466 /// 474343 NM_001006681 /// NM_001006682 /// NM_001006683 /// NM_001282461 /// NM_001282462 /// NM_019003 /// XM_005262008 /// XM_005262009 /// XM_005262010 /// XM_005262011 /// XM_005262016 /// XM_005262017 /// XM_005262018 /// XM_005262019 /// XM_006724588 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 211705_s_at AF356525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF356525.1 /DEF=Homo sapiens sorbin and SH3 domain containing 1 mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=sorbin and SH3 domain containing 1 /DB_XREF=gi:13650130 /FL=gb:AF356525.1 AF356525 sorbin and SH3 domain containing 1 SORBS1 10580 NM_001034954 /// NM_001034955 /// NM_001034956 /// NM_001034957 /// NM_001290294 /// NM_001290295 /// NM_001290296 /// NM_001290297 /// NM_001290298 /// NM_006434 /// NM_015385 /// NM_024991 /// XM_005269404 /// XM_005269405 /// XM_005269406 /// XM_005269411 /// XM_005269412 /// XM_005269414 /// XM_005269424 /// XM_005269425 /// XM_005269427 /// XM_005269431 /// XM_005269437 /// XM_005269439 /// XM_005269440 /// XM_006717560 /// XM_006717561 /// XM_006717562 /// XM_006717563 /// XM_006717564 /// XM_006717565 /// XM_006717566 /// XM_006717567 /// XM_006717568 /// XM_006717569 /// XM_006717570 /// XM_006717571 /// XM_006717572 /// XM_006717573 /// XM_006717574 /// XM_006717575 /// XM_006717576 /// XM_006717577 /// XM_006717578 /// XM_006717579 /// XM_006717580 /// XM_006717581 /// XM_006717582 /// XM_006717583 /// XM_006717584 /// XM_006717585 /// XM_006717586 /// XM_006717587 /// XM_006717588 /// XM_006717589 /// XM_006717590 /// XM_006717591 /// XM_006717592 /// XM_006717593 /// XM_006717594 /// XM_006717595 0006810 // transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from sequence or structural similarity /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005899 // insulin receptor complex // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from sequence or structural similarity /// 0005915 // zonula adherens // traceable author statement /// 0005924 // cell-substrate adherens junction // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0003779 // actin binding // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred by curator /// 0005070 // SH3/SH2 adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation 211706_s_at AY028424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY028424.1 /DEF=Homo sapiens death-preventing kinase mRNA, complete cds. /FEA=mRNA /PROD=death-preventing kinase /DB_XREF=gi:13540813 /FL=gb:AY028424.1 AY028424 cyclin-dependent kinase 19 CDK19 23097 NM_015076 /// XM_005266870 /// XM_005266871 /// XM_005266872 /// XM_005266873 /// XM_006715402 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211707_s_at BC005806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005806.1 /DEF=Homo sapiens, Similar to KIAA0036 gene product, clone MGC:10258, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0036 gene product /DB_XREF=gi:13543280 /FL=gb:BC005806.1 BC005806 IQ motif containing B1 IQCB1 9657 NM_001023570 /// NM_001023571 /// XM_005247911 /// XM_005247912 /// XM_005247913 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 211708_s_at BC005807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005807.1 /DEF=Homo sapiens, clone MGC:10264, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10264) /DB_XREF=gi:13543283 /FL=gb:BC005807.1 BC005807 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation 211709_s_at BC005810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005810.1 /DEF=Homo sapiens, stem cell growth factor; lymphocyte secreted C-type lectin, clone MGC:10378, mRNA, complete cds. /FEA=mRNA /PROD=stem cell growth factor; lymphocyte secretedC-type lectin /DB_XREF=gi:13543291 /FL=gb:BC005810.1 BC005810 C-type lectin domain family 11, member A CLEC11A 6320 NM_002975 0008284 // positive regulation of cell proliferation // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0008083 // growth factor activity // inferred from direct assay /// 0030246 // carbohydrate binding // non-traceable author statement 211710_x_at BC005817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005817.1 /DEF=Homo sapiens, ribosomal protein L4, clone MGC:11073, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L4 /DB_XREF=gi:13543303 /FL=gb:BC005817.1 BC005817 ribosomal protein L4 /// small nucleolar RNA, C/D box 16 /// small nucleolar RNA, C/D box 18A /// small nucleolar RNA, C/D box 18B /// small nucleolar RNA, C/D box 18C RPL4 /// SNORD16 /// SNORD18A /// SNORD18B /// SNORD18C 6124 /// 595097 /// 595098 /// 595099 /// 595100 NM_000968 /// NR_002440 /// NR_002441 /// NR_002442 /// NR_002443 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211711_s_at BC005821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005821.1 /DEF=Homo sapiens, phosphatase and tensin homolog (mutated in multiple advanced cancers 1), clone MGC:11227, mRNA, complete cds. /FEA=mRNA /PROD=phosphatase and tensin homolog (mutated inmultiple advanced cancers 1) /DB_XREF=gi:13543309 /FL=gb:BC005821.1 BC005821 phosphatase and tensin homolog PTEN 5728 NM_000314 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement 211712_s_at BC005830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005830.1 /DEF=Homo sapiens, clone MGC:1925, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:1925) /DB_XREF=gi:13543331 /FL=gb:BC005830.1 BC005830 annexin A9 ANXA9 8416 NM_003568 /// XM_005245539 0007268 // synaptic transmission // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement 211713_x_at BC005832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005832.1 /DEF=Homo sapiens, KIAA0101 gene product, clone MGC:2250, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0101 gene product /DB_XREF=gi:13543336 /FL=gb:BC005832.1 BC005832 KIAA0101 KIAA0101 9768 NM_001029989 /// NM_014736 /// NR_109934 0006260 // DNA replication // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0019985 // translesion synthesis // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 211714_x_at BC005838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005838.1 /DEF=Homo sapiens, tubulin, beta 5, clone MGC:2440, mRNA, complete cds. /FEA=mRNA /PROD=tubulin, beta 5 /DB_XREF=gi:13543349 /FL=gb:BC005838.1 BC005838 tubulin, beta class I TUBB 203068 NM_001293212 /// NM_001293213 /// NM_001293214 /// NM_001293215 /// NM_001293216 /// NM_178014 /// NR_120608 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0009987 // cellular process // inferred from direct assay /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay 211715_s_at BC005844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005844.1 /DEF=Homo sapiens, clone MGC:2723, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2723) /DB_XREF=gi:13543366 /FL=gb:BC005844.1 BC005844 3-hydroxybutyrate dehydrogenase, type 1 BDH1 622 NM_004051 /// NM_203314 /// NM_203315 /// XM_005269352 /// XM_005269355 0001889 // liver development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // traceable author statement /// 0046952 // ketone body catabolic process // traceable author statement /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003858 // 3-hydroxybutyrate dehydrogenase activity // inferred from direct assay /// 0003858 // 3-hydroxybutyrate dehydrogenase activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 211716_x_at BC005851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005851.1 /DEF=Homo sapiens, Rho GDP dissociation inhibitor (GDI) alpha, clone MGC:2810, mRNA, complete cds. /FEA=mRNA /PROD=Rho GDP dissociation inhibitor (GDI) alpha /DB_XREF=gi:13543380 /FL=gb:BC005851.1 BC005851 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211717_at BC005853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005853.1 /DEF=Homo sapiens, clone MGC:2861, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2861) /DB_XREF=gi:13543385 /FL=gb:BC005853.1 BC005853 ankyrin repeat domain 40 ANKRD40 91369 NM_052855 0005515 // protein binding // inferred from electronic annotation 211718_at BC005856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005856.1 /DEF=Homo sapiens, clone MGC:2889, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2889) /DB_XREF=gi:13543393 /FL=gb:BC005856.1 BC005856 uncharacterized protein MGC2889 MGC2889 84789 NM_032703 /// NR_026877 211719_x_at BC005858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005858.1 /DEF=Homo sapiens, clone MGC:3255, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3255) /DB_XREF=gi:13543399 /FL=gb:BC005858.1 BC005858 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 211720_x_at BC005863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005863.1 /DEF=Homo sapiens, ribosomal protein, large, P0, clone MGC:3679, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein, large, P0 /DB_XREF=gi:13543411 /FL=gb:BC005863.1 BC005863 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211721_s_at BC005868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005868.1 /DEF=Homo sapiens, Similar to zinc finger protein 304, clone MGC:4079, mRNA, complete cds. /FEA=mRNA /PROD=Similar to zinc finger protein 304 /DB_XREF=gi:13543418 /FL=gb:BC005868.1 BC005868 zinc finger protein 551 ZNF551 90233 NM_001270938 /// NM_138347 /// NR_073102 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211722_s_at BC005872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005872.1 /DEF=Homo sapiens, clone MGC:4255, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4255) /DB_XREF=gi:13543429 /FL=gb:BC005872.1 BC005872 histone deacetylase 6 HDAC6 10013 NM_006044 /// XM_005272564 /// XM_005272565 /// XM_005272566 /// XM_005272568 /// XM_006724525 /// XR_246712 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from mutant phenotype /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010033 // response to organic substance // inferred from mutant phenotype /// 0010469 // regulation of receptor activity // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010727 // negative regulation of hydrogen peroxide metabolic process // inferred by curator /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0032418 // lysosome localization // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0035967 // cellular response to topologically incorrect protein // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0043241 // protein complex disassembly // inferred from electronic annotation /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051354 // negative regulation of oxidoreductase activity // inferred by curator /// 0051788 // response to misfolded protein // inferred from mutant phenotype /// 0060632 // regulation of microtubule-based movement // inferred by curator /// 0060765 // regulation of androgen receptor signaling pathway // traceable author statement /// 0070201 // regulation of establishment of protein localization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from mutant phenotype /// 0070845 // polyubiquitinated misfolded protein transport // inferred from mutant phenotype /// 0070846 // Hsp90 deacetylation // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0071218 // cellular response to misfolded protein // inferred from electronic annotation /// 0090035 // positive regulation of chaperone-mediated protein complex assembly // inferred from mutant phenotype /// 0090042 // tubulin deacetylation // inferred from direct assay /// 0090042 // tubulin deacetylation // inferred from sequence or structural similarity /// 1901300 // positive regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0030286 // dynein complex // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from direct assay /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042903 // tubulin deacetylase activity // inferred from direct assay /// 0042903 // tubulin deacetylase activity // inferred from sequence or structural similarity /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 211724_x_at BC005883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005883.1 /DEF=Homo sapiens, clone MGC:4732, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4732) /DB_XREF=gi:13543450 /FL=gb:BC005883.1 BC005883 missing oocyte, meiosis regulator, homolog (Drosophila) MIOS 54468 NM_019005 /// XM_005249780 /// XM_005249781 /// XM_005249782 /// XM_005249783 /// XM_005249784 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 211725_s_at BC005884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005884.1 /DEF=Homo sapiens, clone MGC:4736, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:4736) /DB_XREF=gi:13543452 /FL=gb:BC005884.1 BC005884 BH3 interacting domain death agonist BID 637 NM_001196 /// NM_001244567 /// NM_001244569 /// NM_001244570 /// NM_001244572 /// NM_197966 /// NM_197967 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0090150 // establishment of protein localization to membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // traceable author statement /// 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211726_s_at BC005894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005894.1 /DEF=Homo sapiens, flavin containing monooxygenase 2, clone MGC:14468, mRNA, complete cds. /FEA=mRNA /PROD=flavin containing monooxygenase 2 /DB_XREF=gi:13543471 /FL=gb:BC005894.1 BC005894 flavin containing monooxygenase 2 (non-functional) FMO2 2327 NM_001460 /// XM_005245039 /// XR_426768 0006082 // organic acid metabolic process // inferred from direct assay /// 0006739 // NADP metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0009404 // toxin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070995 // NADPH oxidation // inferred from direct assay /// 0072592 // oxygen metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // traceable author statement /// 0004499 // N,N-dimethylaniline monooxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 211727_s_at BC005895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005895.1 /DEF=Homo sapiens, COX11 (yeast) homolog, cytochrome c oxidase assembly protein, clone MGC:14469, mRNA, complete cds. /FEA=mRNA /PROD=COX11 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:13543474 /FL=gb:BC005895.1 BC005895 cytochrome c oxidase assembly homolog 11 (yeast) COX11 1353 NM_001162861 /// NM_001162862 /// NM_004375 /// NR_027941 /// NR_027942 /// XM_006721704 /// XM_006721705 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 211728_s_at BC005896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005896.1 /DEF=Homo sapiens, hyaluronoglucosaminidase 3, clone MGC:14472, mRNA, complete cds. /FEA=mRNA /PROD=hyaluronoglucosaminidase 3 /DB_XREF=gi:13543476 /FL=gb:BC005896.1 BC005896 hyaluronoglucosaminidase 3 HYAL3 8372 NM_001200029 /// NM_001200030 /// NM_001200031 /// NM_001200032 /// NM_003549 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0046677 // response to antibiotic // inferred from expression pattern /// 0051216 // cartilage development // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071493 // cellular response to UV-B // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0033906 // hyaluronoglucuronidase activity // inferred from direct assay 211729_x_at BC005902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005902.1 /DEF=Homo sapiens, Similar to biliverdin reductase A, clone MGC:14491, mRNA, complete cds. /FEA=mRNA /PROD=Similar to biliverdin reductase A /DB_XREF=gi:13543488 /FL=gb:BC005902.1 BC005902 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211730_s_at BC005903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005903.1 /DEF=Homo sapiens, polymerase (RNA) II (DNA directed) polypeptide L (7.6kD), clone MGC:14494, mRNA, complete cds. /FEA=mRNA /PROD=polymerase (RNA) II (DNA directed) polypeptide L(7.6kD) /DB_XREF=gi:13543491 /FL=gb:BC005903.1 BC005903 polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa POLR2L 5441 NM_021128 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0008270 // zinc ion binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 211731_x_at BC005904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005904.1 /DEF=Homo sapiens, synovial sarcoma, X breakpoint 3, clone MGC:14495, mRNA, complete cds. /FEA=mRNA /PROD=synovial sarcoma, X breakpoint 3 /DB_XREF=gi:13543493 /FL=gb:BC005904.1 BC005904 synovial sarcoma, X breakpoint 3 SSX3 10214 NM_021014 /// NM_175711 /// XM_005272579 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 211732_x_at BC005907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005907.1 /DEF=Homo sapiens, Similar to histamine N-methyltransferase, clone MGC:14500, mRNA, complete cds. /FEA=mRNA /PROD=Similar to histamine N-methyltransferase /DB_XREF=gi:13543496 /FL=gb:BC005907.1 BC005907 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 211733_x_at BC005911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005911.1 /DEF=Homo sapiens, sterol carrier protein 2, clone MGC:14505, mRNA, complete cds. /FEA=mRNA /PROD=sterol carrier protein 2 /DB_XREF=gi:13543502 /FL=gb:BC005911.1 BC005911 sterol carrier protein 2 SCP2 6342 NM_001007098 /// NM_001007099 /// NM_001007100 /// NM_001007250 /// NM_001193599 /// NM_001193600 /// NM_001193617 /// NM_002979 /// XM_005271103 /// XM_005271104 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015914 // phospholipid transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // non-traceable author statement /// 0032959 // inositol trisphosphate biosynthetic process // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045940 // positive regulation of steroid metabolic process // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 1901373 // lipid hydroperoxide transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation /// 0033814 // propanoyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0070538 // oleic acid binding // inferred from direct assay 211734_s_at BC005912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005912.1 /DEF=Homo sapiens, Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, clone MGC:14507, mRNA, complete cds. /FEA=mRNA /PROD=Fc fragment of IgE, high affinity I, receptorfor; alpha polypeptide /DB_XREF=gi:13543505 /FL=gb:BC005912.1 BC005912 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide FCER1A 2205 NM_002001 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001812 // positive regulation of type I hypersensitivity // inferred from electronic annotation /// 0001820 // serotonin secretion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045401 // positive regulation of interleukin-3 biosynthetic process // inferred from electronic annotation /// 0045425 // positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019767 // IgE receptor activity // inferred from electronic annotation /// 0019863 // IgE binding // inferred from electronic annotation 211735_x_at BC005913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005913.1 /DEF=Homo sapiens, surfactant, pulmonary-associated protein C, clone MGC:14509, mRNA, complete cds. /FEA=mRNA /PROD=surfactant, pulmonary-associated protein C /DB_XREF=gi:13543508 /FL=gb:BC005913.1 BC005913 surfactant protein C SFTPC 6440 NM_001172357 /// NM_001172410 /// NM_003018 /// XM_005273598 /// XM_006716379 /// XM_006716380 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070741 // response to interleukin-6 // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071732 // cellular response to nitric oxide // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 211736_at BC005914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005914.1 /DEF=Homo sapiens, clone MGC:14510, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:14510) /DB_XREF=gi:13543511 /FL=gb:BC005914.1 BC005914 Sp2 transcription factor SP2 6668 NM_003110 /// XM_006722023 /// XM_006722024 /// XM_006722025 /// XM_006722026 /// XM_006722027 /// XM_006722028 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211737_x_at BC005916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005916.1 /DEF=Homo sapiens, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1), clone MGC:14512, mRNA, complete cds. /FEA=mRNA /PROD=pleiotrophin (heparin binding growth factor 8,neurite growth-promoting factor 1) /DB_XREF=gi:13543514 /FL=gb:BC005916.1 BC005916 pleiotrophin PTN 5764 NM_002825 /// XM_005250515 /// XM_005250516 0001503 // ossification // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 211738_x_at BC005918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005918.1 /DEF=Homo sapiens, Similar to elastase 3, pancreatic (protease E), clone MGC:14514, mRNA, complete cds. /FEA=mRNA /PROD=Similar to elastase 3, pancreatic (protease E) /DB_XREF=gi:13543517 /FL=gb:BC005918.1 BC005918 chymotrypsin-like elastase family, member 3A CELA3A 10136 NM_005747 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211739_x_at BC005921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005921.1 /DEF=Homo sapiens, chorionic somatomammotropin hormone 1 (placental lactogen), clone MGC:14518, mRNA, complete cds. /FEA=mRNA /PROD=chorionic somatomammotropin hormone 1 (placentallactogen) /DB_XREF=gi:13543525 /FL=gb:BC005921.1 BC005921 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSH2 /// CSHL1 /// GH1 1442 /// 1443 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_020991 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211740_at BC005922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005922.1 /DEF=Homo sapiens, Similar to islet cell autoantigen 1 (69kD), clone MGC:14523, mRNA, complete cds. /FEA=mRNA /PROD=Similar to islet cell autoantigen 1 (69kD) /DB_XREF=gi:13543527 /FL=gb:BC005922.1 BC005922 islet cell autoantigen 1, 69kDa ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 211741_x_at BC005924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005924.1 /DEF=Homo sapiens, pregnancy specific beta-1-glycoprotein 3, clone MGC:14526, mRNA, complete cds. /FEA=mRNA /PROD=pregnancy specific beta-1-glycoprotein 3 /DB_XREF=gi:13543532 /FL=gb:BC005924.1 BC005924 pregnancy specific beta-1-glycoprotein 3 PSG3 5671 NM_021016 0006952 // defense response // traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211742_s_at BC005926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005926.1 /DEF=Homo sapiens, ecotropic viral integration site 2B, clone MGC:14529, mRNA, complete cds. /FEA=mRNA /PROD=ecotropic viral integration site 2B /DB_XREF=gi:13543535 /FL=gb:BC005926.1 BC005926 ecotropic viral integration site 2B EVI2B 2124 NM_006495 /// XM_005257946 0005737 // cytoplasm // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211743_s_at BC005929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005929.1 /DEF=Homo sapiens, proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein), clone MGC:14537, mRNA, complete cds. /FEA=mRNA /PROD=proteoglycan 2, bone marrow (natural killer cellactivator, eosinophil granule major basic protein) /DB_XREF=gi:13543541 /FL=gb:BC005929.1 BC005929 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) PRG2 5553 NM_001243245 /// NM_002728 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008201 // heparin binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211744_s_at BC005930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005930.1 /DEF=Homo sapiens, Similar to CD58 antigen, (lymphocyte function-associated antigen 3), clone MGC:14538, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CD58 antigen, (lymphocytefunction-associated antigen 3) /DB_XREF=gi:13543544 /FL=gb:BC005930.1 BC005930 CD58 molecule CD58 965 NM_001144822 /// NM_001779 /// NR_026665 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 211745_x_at BC005931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005931.1 /DEF=Homo sapiens, hemoglobin, alpha 2, clone MGC:14541, mRNA, complete cds. /FEA=mRNA /PROD=hemoglobin, alpha 2 /DB_XREF=gi:13543547 /FL=gb:BC005931.1 BC005931 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211746_x_at BC005932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005932.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, alpha type, 1, clone MGC:14542, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, alphatype, 1 /DB_XREF=gi:13543550 /FL=gb:BC005932.1 BC005932 proteasome (prosome, macropain) subunit, alpha type, 1 PSMA1 5682 NM_001143937 /// NM_002786 /// NM_148976 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005844 // polysome // traceable author statement /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211747_s_at BC005938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005938.1 /DEF=Homo sapiens, U6 snRNA-associated Sm-like protein, clone MGC:14558, mRNA, complete cds. /FEA=mRNA /PROD=U6 snRNA-associated Sm-like protein /DB_XREF=gi:13543564 /FL=gb:BC005938.1 BC005938 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM5 23658 NM_001130710 /// NM_001139499 /// NM_012322 /// NR_024466 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211748_x_at BC005939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005939.1 /DEF=Homo sapiens, prostaglandin D2 synthase (21kD, brain), clone MGC:14559, mRNA, complete cds. /FEA=mRNA /PROD=prostaglandin D2 synthase (21kD, brain) /DB_XREF=gi:13543567 /FL=gb:BC005939.1 BC005939 prostaglandin D2 synthase 21kDa (brain) PTGDS 5730 NM_000954 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004667 // prostaglandin-D synthase activity // inferred from direct assay /// 0004667 // prostaglandin-D synthase activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005501 // retinoid binding // inferred from sequence or structural similarity /// 0005504 // fatty acid binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation 211749_s_at BC005941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005941.1 /DEF=Homo sapiens, Similar to vesicle-associated membrane protein 3, clone MGC:14563, mRNA, complete cds. /FEA=mRNA /PROD=Similar to vesicle-associated membrane protein3 /DB_XREF=gi:13543573 /FL=gb:BC005941.1 BC005941 vesicle-associated membrane protein 3 VAMP3 9341 NM_004781 0001921 // positive regulation of receptor recycling // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 211750_x_at BC005946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005946.1 /DEF=Homo sapiens, clone MGC:14580, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:14580) /DB_XREF=gi:13543588 /FL=gb:BC005946.1 BC005946 tubulin, alpha 1c TUBA1C 84790 NM_032704 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 211751_at BC005949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005949.1 /DEF=Homo sapiens, similar to rat myomegalin, clone MGC:14586, mRNA, complete cds. /FEA=mRNA /PROD=similar to rat myomegalin /DB_XREF=gi:13543593 /FL=gb:BC005949.1 BC005949 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein pseudogene /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// LOC653513 /// PDE4DIP 9659 /// 653513 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// NR_037182 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 211752_s_at BC005954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005954.1 /DEF=Homo sapiens, clone MGC:14592, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:14592) /DB_XREF=gi:13543602 /FL=gb:BC005954.1 BC005954 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) NDUFS7 374291 NM_024407 /// XM_005259556 /// XR_430138 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 211753_s_at BC005956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005956.1 /DEF=Homo sapiens, relaxin 1 (H1), clone MGC:14599, mRNA, complete cds. /FEA=mRNA /PROD=relaxin 1 (H1) /DB_XREF=gi:13543608 /FL=gb:BC005956.1 BC005956 relaxin 1 RLN1 6013 NM_006911 /// XM_005251541 /// XR_242512 0007165 // signal transduction // non-traceable author statement /// 0007565 // female pregnancy // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 211754_s_at BC005957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005957.1 /DEF=Homo sapiens, solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kD), member 17, clone MGC:14604, mRNA, complete cds. /FEA=mRNA /PROD=solute carrier family 25 (mitochondrial carrier;peroxisomal membrane protein, 34kD), member 17 /DB_XREF=gi:13543611 /FL=gb:BC005957.1 BC005957 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 SLC25A17 10478 NM_001282726 /// NM_001282727 /// NM_006358 /// NR_104235 /// NR_104236 /// NR_104237 /// NR_104238 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015866 // ADP transport // inferred from direct assay /// 0015867 // ATP transport // inferred from genetic interaction /// 0015908 // fatty acid transport // inferred from genetic interaction /// 0035349 // coenzyme A transmembrane transport // inferred from direct assay /// 0035350 // FAD transmembrane transport // inferred from direct assay /// 0043132 // NAD transport // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0080121 // AMP transport // inferred from direct assay /// 1901679 // nucleotide transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005347 // ATP transmembrane transporter activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0015217 // ADP transmembrane transporter activity // inferred from direct assay /// 0015228 // coenzyme A transmembrane transporter activity // inferred from direct assay /// 0015230 // FAD transmembrane transporter activity // inferred from direct assay /// 0044610 // FMN transmembrane transporter activity // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051724 // NAD transporter activity // inferred from direct assay /// 0080122 // AMP transmembrane transporter activity // inferred from direct assay 211755_s_at BC005960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005960.1 /DEF=Homo sapiens, Similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1, clone MGC:14609, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ATP synthase, H+ transporting,mitochondrial F0 complex, subunit b, isoform 1 /DB_XREF=gi:13543617 /FL=gb:BC005960.1 BC005960 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 ATP5F1 515 NM_001688 /// XM_005270929 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // not recorded /// 0015992 // proton transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // not recorded 211756_at BC005961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005961.1 /DEF=Homo sapiens, parathyroid hormone-like hormone, clone MGC:14611, mRNA, complete cds. /FEA=mRNA /PROD=parathyroid hormone-like hormone /DB_XREF=gi:13543620 /FL=gb:BC005961.1 BC005961 parathyroid hormone-like hormone PTHLH 5744 NM_002820 /// NM_198964 /// NM_198965 /// NM_198966 /// XM_005253434 /// XM_006719115 0001501 // skeletal system development // inferred from direct assay /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0016485 // protein processing // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046058 // cAMP metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060649 // mammary gland bud elongation // inferred from electronic annotation /// 0060659 // nipple sheath formation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from direct assay 211758_x_at BC005968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005968.1 /DEF=Homo sapiens, ATP binding protein associated with cell differentiation, clone MGC:14620, mRNA, complete cds. /FEA=mRNA /PROD=ATP binding protein associated with celldifferentiation /DB_XREF=gi:13543638 /FL=gb:BC005968.1 BC005968 thioredoxin domain containing 9 TXNDC9 10190 NM_005783 0045454 // cell redox homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211759_x_at BC005969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005969.1 /DEF=Homo sapiens, clone MGC:14625, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:14625) /DB_XREF=gi:13543641 /FL=gb:BC005969.1 BC005969 tubulin folding cofactor B TBCB 1155 NM_001281 /// XM_006722998 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement 0005515 // protein binding // inferred from physical interaction 211760_s_at BC005974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005974.1 /DEF=Homo sapiens, vesicle-associated membrane protein 4, clone MGC:14658, mRNA, complete cds. /FEA=mRNA /PROD=vesicle-associated membrane protein 4 /DB_XREF=gi:13543647 /FL=gb:BC005974.1 BC005974 vesicle-associated membrane protein 4 VAMP4 8674 NM_001185127 /// NM_003762 /// NM_201994 /// NR_033704 /// XR_426805 0006887 // exocytosis // not recorded /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035493 // SNARE complex assembly // inferred from direct assay /// 0042996 // regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded 211761_s_at BC005975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005975.1 /DEF=Homo sapiens, calcyclin binding protein, clone MGC:14660, mRNA, complete cds. /FEA=mRNA /PROD=calcyclin binding protein /DB_XREF=gi:13543650 /FL=gb:BC005975.1 BC005975 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 211762_s_at BC005978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005978.1 /DEF=Homo sapiens, karyopherin alpha 2 (RAG cohort 1, importin alpha 1), clone MGC:14668, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin alpha 2 (RAG cohort 1, importinalpha 1) /DB_XREF=gi:13543656 /FL=gb:BC005978.1 BC005978 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) KPNA2 3838 NM_002266 0000018 // regulation of DNA recombination // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211763_s_at BC005979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005979.1 /DEF=Homo sapiens, ubiquitin-conjugating enzyme E2B (RAD6 homolog), clone MGC:14670, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-conjugating enzyme E2B (RAD6 homolog) /DB_XREF=gi:13543659 /FL=gb:BC005979.1 BC005979 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 211764_s_at BC005980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005980.1 /DEF=Homo sapiens, ubiquitin-conjugating enzyme E2D 1 (homologous to yeast UBC45), clone MGC:14673, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-conjugating enzyme E2D 1 (homologousto yeast UBC45) /DB_XREF=gi:13543662 /FL=gb:BC005980.1 BC005980 ubiquitin-conjugating enzyme E2D 1 UBE2D1 7321 NM_001204880 /// NM_003338 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 211765_x_at BC005982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005982.1 /DEF=Homo sapiens, peptidylprolyl isomerase A (cyclophilin A), clone MGC:14681, mRNA, complete cds. /FEA=mRNA /PROD=peptidylprolyl isomerase A (cyclophilin A) /DB_XREF=gi:13543665 /FL=gb:BC005982.1 BC005982 peptidylprolyl isomerase A (cyclophilin A) PPIA 5478 NM_021130 /// NM_203430 /// NM_203431 /// XM_005249791 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 211766_s_at BC005989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005989.1 /DEF=Homo sapiens, pancreatic lipase-related protein 2, clone MGC:14790, mRNA, complete cds. /FEA=mRNA /PROD=pancreatic lipase-related protein 2 /DB_XREF=gi:13543678 /FL=gb:BC005989.1 BC005989 pancreatic lipase-related protein 2 PNLIPRP2 5408 NM_005396 /// NR_103727 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // traceable author statement /// 0006968 // cellular defense response // inferred from electronic annotation /// 0007586 // digestion // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019376 // galactolipid catabolic process // inferred from direct assay /// 0044241 // lipid digestion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004620 // phospholipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047372 // acylglycerol lipase activity // inferred from direct assay /// 0047714 // galactolipase activity // inferred from direct assay 211767_at BC005995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005995.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 4933405K01 gene, clone MGC:14799, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 4933405K01 gene /DB_XREF=gi:13543688 /FL=gb:BC005995.1 BC005995 GINS complex subunit 4 (Sld5 homolog) GINS4 84296 NM_032336 /// XM_005273659 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211768_at BC006080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006080.1 /DEF=Homo sapiens, Williams-Beuren syndrome chromosome region 5, clone MGC:12566, mRNA, complete cds. /FEA=mRNA /PROD=Williams-Beuren syndrome chromosome region 5 /DB_XREF=gi:13543865 /FL=gb:BC006080.1 BC006080 linker for activation of T cells family, member 2 LAT2 7462 NM_014146 /// NM_032463 /// NM_032464 /// XM_005250562 0002376 // immune system process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042113 // B cell activation // inferred from direct assay /// 0042113 // B cell activation // traceable author statement /// 0043303 // mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from mutant phenotype 211769_x_at BC006088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006088.1 /DEF=Homo sapiens, tumor differentially expressed 1, clone MGC:12658, mRNA, complete cds. /FEA=mRNA /PROD=tumor differentially expressed 1 /DB_XREF=gi:13543883 /FL=gb:BC006088.1 BC006088 serine incorporator 3 SERINC3 10955 NM_006811 /// NM_198941 1902237 // positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211771_s_at BC006101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006101.1 /DEF=Homo sapiens, Similar to POU domain, class 2, transcription factor 2, clone MGC:12814, mRNA, complete cds. /FEA=mRNA /PROD=Similar to POU domain, class 2, transcriptionfactor 2 /DB_XREF=gi:13543912 /FL=gb:BC006101.1 BC006101 POU class 2 homeobox 2 POU2F2 5452 NM_001207025 /// NM_001207026 /// NM_001247994 /// NM_002698 /// XM_005259009 /// XM_005259010 /// XM_005259011 /// XM_005259012 0002335 // mature B cell differentiation // inferred from electronic annotation /// 0002380 // immunoglobulin secretion involved in immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048305 // immunoglobulin secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 211772_x_at BC006114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006114.1 /DEF=Homo sapiens, Similar to cholinergic receptor, nicotinic, alpha polypeptide 3, clone MGC:12991, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cholinergic receptor, nicotinic,alpha polypeptide 3 /DB_XREF=gi:13543945 /FL=gb:BC006114.1 BC006114 cholinergic receptor, nicotinic, alpha 3 (neuronal) CHRNA3 1136 NM_000743 /// NM_001166694 /// NR_046313 /// XM_006720382 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060084 // synaptic transmission involved in micturition // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 211773_s_at BC006118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006118.1 /DEF=Homo sapiens, Similar to hypothetical protein P1 p373c6, clone MGC:12997, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein P1 p373c6 /DB_XREF=gi:13543957 /FL=gb:BC006118.1 BC006118 zinc finger with KRAB and SCAN domains 3 ZKSCAN3 80317 NM_001242894 /// NM_001242895 /// NM_024493 /// XM_005249423 /// XM_005249424 /// XM_006715215 /// XM_006715216 /// XM_006715217 /// XM_006715218 /// XM_006715219 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211774_s_at BC006122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006122.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 1810037K07 gene, clone MGC:13015, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 1810037K07 gene /DB_XREF=gi:13543966 /FL=gb:BC006122.1 BC006122 methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria MMACHC 25974 NM_015506 /// XM_005270724 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009235 // cobalamin metabolic process // traceable author statement /// 0009236 // cobalamin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0031419 // cobalamin binding // inferred from electronic annotation 211775_x_at BC006134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006134.1 /DEF=Homo sapiens, clone MGC:13053, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13053) /DB_XREF=gi:13543996 /FL=gb:BC006134.1 BC006134 RecName: Full=Putative uncharacterized protein MGC13053; /// MGC13053 /// RP11-770J1.4 211776_s_at BC006141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006141.1 /DEF=Homo sapiens, Similar to erythrocyte protein band 4.1-like 3, clone MGC:13087, mRNA, complete cds. /FEA=mRNA /PROD=Similar to erythrocyte protein band 4.1-like 3 /DB_XREF=gi:13544008 /FL=gb:BC006141.1 BC006141 erythrocyte membrane protein band 4.1-like 3 EPB41L3 23136 NM_001281533 /// NM_001281534 /// NM_001281535 /// NM_012307 /// XM_005258085 /// XM_005258086 /// XM_005258087 /// XM_005258088 /// XM_005258089 /// XM_005258090 /// XM_005258091 /// XM_006722301 /// XM_006722302 /// XM_006722303 /// XM_006722304 /// XM_006722305 /// XM_006722306 /// XM_006722307 /// XM_006722308 /// XM_006722309 /// XM_006722310 /// XM_006722311 /// XM_006722312 /// XM_006722313 /// XM_006722314 /// XM_006722315 /// XM_006722316 0002175 // protein localization to paranode region of axon // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0030865 // cortical cytoskeleton organization // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 211778_s_at BC006148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006148.1 /DEF=Homo sapiens, putative zinc finger protein from EUROIMAGE 566589, clone MGC:13109, mRNA, complete cds. /FEA=mRNA /PROD=putative zinc finger protein from EUROIMAGE566589 /DB_XREF=gi:13544025 /FL=gb:BC006148.1 BC006148 ovo-like zinc finger 2 OVOL2 58495 NM_021220 /// XM_005260783 0001525 // angiogenesis // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010837 // regulation of keratinocyte proliferation // inferred from electronic annotation /// 0010837 // regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0045617 // negative regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0060214 // endocardium formation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred by curator 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211779_x_at BC006155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006155.1 /DEF=Homo sapiens, clone MGC:13188, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13188) /DB_XREF=gi:13544040 /FL=gb:BC006155.1 BC006155 adaptor-related protein complex 2, alpha 2 subunit AP2A2 161 NM_001242837 /// NM_012305 /// XM_006718159 /// XM_006718160 /// XR_242779 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // non-traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 211780_x_at BC006163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006163.1 /DEF=Homo sapiens, Similar to dynactin 1 (p150, Glued (Drosophila) homolog), clone MGC:13209, mRNA, complete cds. /FEA=mRNA /PROD=Similar to dynactin 1 (p150, Glued (Drosophila)homolog) /DB_XREF=gi:13544059 /FL=gb:BC006163.1 BC006163 dynactin 1 DCTN1 1639 NM_001135040 /// NM_001135041 /// NM_001190836 /// NM_001190837 /// NM_004082 /// NM_023019 /// NR_033935 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 211781_x_at BC006164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006164.1 /DEF=Homo sapiens, clone MGC:13219, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:13219) /DB_XREF=gi:13544062 /FL=gb:BC006164.1 BC006164 211782_at BC006170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006170.1 /DEF=Homo sapiens, Similar to iduronate 2-sulfatase (Hunter syndrome), clone MGC:13238, mRNA, complete cds. /FEA=mRNA /PROD=Similar to iduronate 2-sulfatase (Huntersyndrome) /DB_XREF=gi:13544076 /FL=gb:BC006170.1 BC006170 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211783_s_at BC006177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006177.1 /DEF=Homo sapiens, Similar to metastasis associated 1, clone MGC:13258, mRNA, complete cds. /FEA=mRNA /PROD=Similar to metastasis associated 1 /DB_XREF=gi:13544097 /FL=gb:BC006177.1 BC006177 metastasis associated 1 MTA1 9112 NM_001203258 /// NM_004689 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0033363 // secretory granule organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211784_s_at BC006181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006181.1 /DEF=Homo sapiens, Similar to splicing factor, arginineserine-rich 2 (SC-35), clone MGC:2622, mRNA, complete cds. /FEA=mRNA /PROD=Similar to splicing factor, arginineserine-rich2 (SC-35) /DB_XREF=gi:13544106 /FL=gb:BC006181.1 BC006181 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 211786_at BC006196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006196.1 /DEF=Homo sapiens, tumor necrosis factor receptor superfamily, member 9, clone MGC:2172, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor receptor superfamily,member 9 /DB_XREF=gi:13623200 /FL=gb:BC006196.1 BC006196 tumor necrosis factor receptor superfamily, member 9 TNFRSF9 3604 NM_001561 /// XM_006710618 0006915 // apoptotic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 2001180 // negative regulation of interleukin-10 secretion // inferred from electronic annotation /// 2001183 // negative regulation of interleukin-12 secretion // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from electronic annotation 211787_s_at BC006210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006210.1 /DEF=Homo sapiens, Similar to eukaryotic translation initiation factor 4A, isoform 1, clone MGC:8484, mRNA, complete cds. /FEA=mRNA /PROD=Similar to eukaryotic translation initiationfactor 4A, isoform 1 /DB_XREF=gi:13623224 /FL=gb:BC006210.1 BC006210 eukaryotic translation initiation factor 4A1 /// uncharacterized LOC101928634 /// SENP3-EIF4A1 readthrough (NMD candidate) /// small nucleolar RNA, H/ACA box 48 /// small nucleolar RNA, H/ACA box 67 /// small nucleolar RNA, C/D box 10 EIF4A1 /// LOC101928634 /// SENP3-EIF4A1 /// SNORA48 /// SNORA67 /// SNORD10 1973 /// 26781 /// 652965 /// 652966 /// 100533955 /// 101928634 NM_001204510 /// NM_001416 /// NR_002604 /// NR_002912 /// NR_002918 /// NR_037926 /// XR_244579 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211788_s_at AF319573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF319573.1 /DEF=Homo sapiens clone T2P4 3-5 exonuclease TREX2 (TREX2) mRNA, complete cds. /FEA=CDS /GEN=TREX2 /PROD=3-5 exonuclease TREX2 /DB_XREF=gi:12751322 /UG=Hs.6487 Xq28, 2000bp sequence contg. ORF /FL=gb:AF319573.1 AF319573 HAUS augmin-like complex, subunit 7 /// three prime repair exonuclease 2 HAUS7 /// TREX2 11219 /// 55559 NM_017518 /// NM_080699 /// NM_080700 /// NM_080701 /// NM_207106 /// NM_207107 /// NR_073156 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070652 // HAUS complex // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008296 // 3'-5'-exodeoxyribonuclease activity // inferred from direct assay /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211789_s_at AF312918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312918.1 /DEF=Homo sapiens MondoA mRNA, complete cds. /FEA=CDS /PROD=MondoA /DB_XREF=gi:11321340 /UG=Hs.52081 KIAA0867 protein /FL=gb:AF312918.1 AF312918 MLX interacting protein MLXIP 22877 NM_014938 /// XM_006719290 /// XM_006719291 /// XM_006719292 /// XM_006719293 /// XM_006719294 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 211790_s_at AF010404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF010404.1 /DEF=Homo sapiens ALR mRNA, complete cds. /FEA=CDS /GEN=ALR /PROD=ALR /DB_XREF=gi:2358286 /UG=Hs.153638 myeloidlymphoid or mixed-lineage leukemia 2 /FL=gb:AF010404.1 AF010404 lysine (K)-specific methyltransferase 2D KMT2D 8085 NM_003482 /// XM_005269162 /// XM_006719614 /// XM_006719615 /// XM_006719616 0001555 // oocyte growth // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0035097 // histone methyltransferase complex // inferred from physical interaction 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211791_s_at AF044253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF044253.1 /DEF=Homo sapiens potassium channel beta 2 subunit (HKvbeta2.2) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=HKvbeta2.2 /PROD=potassium channel beta 2 subunit /DB_XREF=gi:2827465 /UG=Hs.298184 potassium voltage-gated channel, shaker-related subfamily, beta member 2 /FL=gb:AF044253.1 AF044253 potassium voltage-gated channel, shaker-related subfamily, beta member 2 KCNAB2 8514 NM_001199860 /// NM_001199861 /// NM_001199862 /// NM_001199863 /// NM_003636 /// NM_172130 /// XM_005263511 /// XM_005263512 /// XM_005263513 /// XM_005263514 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 211792_s_at U17074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U17074.1 /DEF=Human CDK6 inhibitor p18 mRNA, complete cds. /FEA=CDS /PROD=p18 /DB_XREF=gi:639713 /UG=Hs.4854 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) /FL=gb:U17074.1 U17074 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) CDKN2C 1031 NM_001262 /// NM_078626 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 211793_s_at AF260261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF260261.1 /DEF=Homo sapiens Abl-interactor protein 2b (ABI2B) mRNA, complete cds. /FEA=CDS /GEN=ABI2B /PROD=Abl-interactor protein 2b /DB_XREF=gi:7839523 /UG=Hs.256315 abl-interactor 12 (SH3-containing protein) /FL=gb:AF260261.1 AF260261 abl-interactor 2 ABI2 10152 NM_001282925 /// NM_001282926 /// NM_001282927 /// NM_001282932 /// NM_005759 /// XM_005246217 /// XM_005246218 /// XM_005246221 /// XM_005246222 /// XM_005246223 /// XM_005246224 /// XM_005246225 /// XM_005246226 /// XM_005246229 /// XM_006712174 /// XM_006712175 /// XM_006712176 /// XM_006712177 /// XM_006712178 /// XM_006712179 /// XM_006712180 /// XM_006712181 /// XM_006712182 /// XM_006712183 /// XM_006712184 /// XM_006712185 /// XM_006712186 0006928 // cellular component movement // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // traceable author statement /// 0019900 // kinase binding // non-traceable author statement /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 211794_at AF198052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF198052.1 /DEF=Homo sapiens EVH1 domain binding protein mRNA, complete cds. /FEA=CDS /PROD=EVH1 domain binding protein /DB_XREF=gi:7416992 /UG=Hs.58435 FYN-binding protein (FYB-120130) /FL=gb:AF198052.1 AF198052 FYN binding protein FYB 2533 NM_001243093 /// NM_001465 /// NM_199335 /// XM_006714464 /// XM_006714465 /// XM_006714466 0006468 // protein phosphorylation // traceable author statement /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 211795_s_at AF198052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF198052.1 /DEF=Homo sapiens EVH1 domain binding protein mRNA, complete cds. /FEA=CDS /PROD=EVH1 domain binding protein /DB_XREF=gi:7416992 /UG=Hs.58435 FYN-binding protein (FYB-120130) /FL=gb:AF198052.1 AF198052 FYN binding protein FYB 2533 NM_001243093 /// NM_001465 /// NM_199335 /// XM_006714464 /// XM_006714465 /// XM_006714466 0006468 // protein phosphorylation // traceable author statement /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 211796_s_at AF043179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043179.1 /DEF=Homo sapiens T cell receptor beta chain (TCRBV13S1-TCRBJ2S1) mRNA, complete cds. /FEA=CDS /GEN=TCRBV13S1-TCRBJ2S1 /PROD=T cell receptor beta chain /DB_XREF=gi:3002924 /UG=Hs.303157 T cell receptor beta locus /FL=gb:AF043179.1 AF043179 T cell receptor beta constant 1 TRBC1 28639 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0043382 // positive regulation of memory T cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from electronic annotation /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0045519 // interleukin-23 receptor binding // inferred from direct assay /// 0045519 // interleukin-23 receptor binding // inferred from electronic annotation 211797_s_at U62296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62296.1 /DEF=Human transcription factor NF-YC subunit mRNA, complete cds. /FEA=CDS /PROD=transcription factor NF-YC subunit /DB_XREF=gi:1669493 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:U62296.1 U62296 nuclear transcription factor Y, gamma NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211798_x_at AB001733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB001733.1 /DEF=Homo sapiens mRNA for single-chain antibody, complete cds. /FEA=CDS /PROD=single-chain antibody /DB_XREF=gi:1902831 /UG=Hs.289110 immunoglobulin lambda joining 3 /FL=gb:AB001733.1 gb:AB001736.1 AB001733 immunoglobulin lambda joining 3 IGLJ3 28831 211799_x_at U62824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U62824.1 /DEF=Homo sapiens HLA class I heavy chain (HLA-Cw*1701) mRNA, complete cds. /FEA=CDS /GEN=HLA-Cw*1701 /PROD=HLA class I heavy chain /DB_XREF=gi:1575443 /UG=Hs.287811 H.sapiens mRNA for HLA-C alpha chain (Cw*1701) /FL=gb:U62824.1 U62824 major histocompatibility complex, class I, C HLA-C 3107 NM_001243042 /// NM_002117 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005102 // receptor binding // not recorded /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay 211800_s_at AF017306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF017306.1 /DEF=Homo sapiens deubiquitinating enzyme UnpES (UNP) mRNA, complete cds. /FEA=CDS /GEN=UNP /PROD=UnpES /DB_XREF=gi:2656142 /UG=Hs.77500 ubiquitin specific protease 4 (proto-oncogene) /FL=gb:AF017306.1 AF017306 ubiquitin specific peptidase 4 (proto-oncogene) USP4 7375 NM_001251877 /// NM_003363 /// NM_199443 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211801_x_at AF329637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF329637.1 /DEF=Homo sapiens mitofusin 1 mRNA, nuclear gene for mitochondrial protein, complete cds. /FEA=CDS /PROD=mitofusin 1 precursor /DB_XREF=gi:12744895 /UG=Hs.197877 hypothetical protein FLJ20693 /FL=gb:AF329637.1 AF329637 mitofusin 1 MFN1 55669 NM_017927 /// NM_033540 /// XM_005247595 /// XM_005247596 0006184 // GTP catabolic process // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211802_x_at AF227750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF227750.1 /DEF=Homo sapiens voltage-dependent calcium channel alpha 1G subunit isoform bcef (CACNA1G) mRNA, complete cds. /FEA=CDS /GEN=CACNA1G /PROD=voltage-dependent calcium channel alpha 1Gsubunit isoform bcef /DB_XREF=gi:7159272 /UG=Hs.194746 calcium channel, voltage-dependent, alpha 1G subunit /FL=gb:AF227750.1 AF227750 calcium channel, voltage-dependent, T type, alpha 1G subunit CACNA1G 8913 NM_001256324 /// NM_001256325 /// NM_001256326 /// NM_001256327 /// NM_001256328 /// NM_001256329 /// NM_001256330 /// NM_001256331 /// NM_001256332 /// NM_001256333 /// NM_001256334 /// NM_001256359 /// NM_001256360 /// NM_001256361 /// NM_018896 /// NM_198376 /// NM_198377 /// NM_198378 /// NM_198379 /// NM_198380 /// NM_198382 /// NM_198383 /// NM_198384 /// NM_198385 /// NM_198386 /// NM_198387 /// NM_198388 /// NM_198396 /// NM_198397 /// NR_046054 /// NR_046055 /// NR_046056 /// NR_046057 /// NR_046058 /// XM_006722160 /// XM_006722161 0001508 // action potential // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0010045 // response to nickel cation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008332 // low voltage-gated calcium channel activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 211803_at AB012305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012305.1 /DEF=Homo sapiens mRNA for d-HSCDK2, complete cds. /FEA=CDS /GEN=CDK2deltaT /PROD=d-HSCDK2 /DB_XREF=gi:3551190 /UG=Hs.19192 cyclin-dependent kinase 2 /FL=gb:AB012305.1 AB012305 cyclin-dependent kinase 2 CDK2 1017 NM_001290230 /// NM_001798 /// NM_052827 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031571 // mitotic G1 DNA damage checkpoint // traceable author statement /// 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051298 // centrosome duplication // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060968 // regulation of gene silencing // inferred from direct assay /// 0071732 // cellular response to nitric oxide // traceable author statement 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211804_s_at AB012305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB012305.1 /DEF=Homo sapiens mRNA for d-HSCDK2, complete cds. /FEA=CDS /GEN=CDK2deltaT /PROD=d-HSCDK2 /DB_XREF=gi:3551190 /UG=Hs.19192 cyclin-dependent kinase 2 /FL=gb:AB012305.1 AB012305 cyclin-dependent kinase 2 CDK2 1017 NM_001290230 /// NM_001798 /// NM_052827 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031571 // mitotic G1 DNA damage checkpoint // traceable author statement /// 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051298 // centrosome duplication // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060968 // regulation of gene silencing // inferred from direct assay /// 0071732 // cellular response to nitric oxide // traceable author statement 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211805_s_at AF108389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF108389.1 /DEF=Homo sapiens sodiumcalcium exchanger isoform NaCa3 (NCX1) mRNA, complete cds. /FEA=CDS /GEN=NCX1 /PROD=sodiumcalcium exchanger isoform NaCa3 /DB_XREF=gi:6453728 /UG=Hs.129763 solute carrier family 8 (sodiumcalcium exchanger), member 1 /FL=gb:AF108389.1 AF108389 solute carrier family 8 (sodium/calcium exchanger), member 1 SLC8A1 6546 NM_001112800 /// NM_001112801 /// NM_001112802 /// NM_001252624 /// NM_021097 /// XM_005264512 /// XM_005264513 /// XM_005264514 /// XM_006712080 /// XM_006712081 /// XM_006712082 /// XM_006712083 /// XM_006712084 /// XM_006712085 /// XM_006712086 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred by curator /// 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014829 // vascular smooth muscle contraction // inferred from sequence or structural similarity /// 0021537 // telencephalon development // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044557 // relaxation of smooth muscle // inferred from sequence or structural similarity /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // inferred by curator /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // traceable author statement /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071436 // sodium ion export // inferred from direct assay /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity /// 0097369 // sodium ion import // inferred from direct assay /// 1901660 // calcium ion export // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0005432 // calcium:sodium antiporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 211806_s_at D87291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87291.1 /DEF=Human mRNA for inward rectifier potassium channel, complete cds. /FEA=CDS /PROD=inward rectifier potassium channel /DB_XREF=gi:1772441 /UG=Hs.17287 potassium inwardly-rectifying channel, subfamily J, member 15 /FL=gb:D87291.1 D87291 potassium inwardly-rectifying channel, subfamily J, member 15 KCNJ15 3772 NM_001276435 /// NM_001276436 /// NM_001276437 /// NM_001276438 /// NM_001276439 /// NM_002243 /// NM_170736 /// NM_170737 /// XM_005260975 /// XM_005260976 /// XM_006724002 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211807_x_at AF152521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152521.1 /DEF=Homo sapiens protocadherin gamma B5 short form protein (PCDH-gamma-B5) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-B5 /PROD=protocadherin gamma B5 short form protein /DB_XREF=gi:5457089 /UG=Hs.283790 protocadherin gamma subfamily B, 5 /FL=gb:AF152521.1 AF152521 protocadherin gamma subfamily B, 5 PCDHGB5 56101 NM_018925 /// NM_032099 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211808_s_at U85962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U85962.3 /DEF=Homo sapiens CREB-binding protein mRNA, complete cds. /FEA=CDS /PROD=CREB-binding protein /DB_XREF=gi:4433815 /UG=Hs.23598 CREB binding protein (Rubinstein-Taybi syndrome) /FL=gb:U85962.3 U85962 CREB binding protein CREBBP 1387 NM_001079846 /// NM_004380 /// XM_005255124 /// XM_005255125 /// XM_006720848 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // traceable author statement /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042733 // embryonic digit morphogenesis // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001102 // RNA polymerase II activating transcription factor binding // traceable author statement /// 0001105 // RNA polymerase II transcription coactivator activity // traceable author statement /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from physical interaction /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043426 // MRF binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 211809_x_at M59217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M59217.1 /DEF=Human collagen type XIII alpha-1 mRNA, complete cds. /FEA=CDS /GEN=COL13A1 /PROD=alpha-1 type XIII collagen /DB_XREF=gi:178319 /UG=Hs.211933 collagen, type XIII, alpha 1 /FL=gb:M59217.1 M59217 collagen, type XIII, alpha 1 COL13A1 1305 NM_001130103 /// NM_005203 /// NM_080798 /// NM_080799 /// NM_080800 /// NM_080801 /// NM_080802 /// NM_080803 /// NM_080804 /// NM_080805 /// NM_080806 /// NM_080807 /// NM_080808 /// NM_080809 /// NM_080810 /// NM_080811 /// NM_080812 /// NM_080813 /// NM_080814 /// NM_080815 /// XM_006717632 0001503 // ossification // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from physical interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from expression pattern /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005600 // collagen type XIII trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay 211810_s_at D25284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D25284.1 /DEF=Human mRNA for alternative spliced product of galactocerebrosidase, complete cds. /FEA=CDS /PROD=alternative spliced product ofgalactocerebrosidase /DB_XREF=gi:457445 /UG=Hs.273 galactosylceramidase (Krabbe disease) /FL=gb:D25284.1 D25284 galactosylceramidase GALC 2581 NM_000153 /// NM_001037525 /// NM_001201401 /// NM_001201402 /// XR_245677 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006683 // galactosylceramide catabolic process // inferred from sequence or structural similarity /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004336 // galactosylceramidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 211811_s_at AF152484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152484.1 /DEF=Homo sapiens protocadherin alpha 6 short form protein (PCDH-alpha6) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-alpha6 /PROD=protocadherin alpha 6 short form protein /DB_XREF=gi:5457016 /UG=Hs.247737 protocadherin alpha 6 /FL=gb:AF152484.1 AF152484 protocadherin alpha 5 /// protocadherin alpha 6 PCDHA5 /// PCDHA6 56142 /// 56143 NM_018908 /// NM_018909 /// NM_031501 /// NM_031848 /// NM_031849 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 211812_s_at AB050856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB050856.1 /DEF=Homo sapiens beta3GalNAcT-1 mRNA for globoside synthase, complete cds, clone:type 2. /FEA=CDS /GEN=beta3GalNAcT-1 /PROD=globoside synthase /DB_XREF=gi:11136456 /UG=Hs.267695 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 /FL=gb:AB050856.1 AB050856 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) B3GALNT1 8706 NM_001038628 /// NM_003781 /// NM_033167 /// NM_033168 /// NM_033169 /// XM_005247859 /// XM_005247861 /// XM_005247862 /// XM_005247864 /// XM_006713802 /// XM_006713803 /// XM_006713804 /// XM_006713805 /// XM_006713806 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047273 // galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity // inferred from electronic annotation 211813_x_at AF138303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF138303.1 /DEF=Homo sapiens decorin D mRNA, complete cds, alternatively spliced. /FEA=CDS /PROD=decorin D /DB_XREF=gi:7381210 /UG=Hs.76152 decorin /FL=gb:AF138303.1 AF138303 decorin DCN 1634 NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 211814_s_at AF112857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112857.1 /DEF=Homo sapiens cyclin E2 splice variant 1 mRNA, complete cds. /FEA=CDS /PROD=cyclin E2 splice variant 1 /DB_XREF=gi:4092787 /UG=Hs.30464 cyclin E2 /FL=gb:AF112857.1 AF112857 cyclin E2 CCNE2 9134 NM_004702 /// NM_057735 /// NM_057749 0000075 // cell cycle checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 211815_s_at AF219138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF219138.1 /DEF=Homo sapiens GGA3 long isoform mRNA, alternatively spliced, complete cds. /FEA=CDS /PROD=GGA3 long isoform /DB_XREF=gi:7229485 /UG=Hs.87726 KIAA0154 protein; ADP-ribosylation factor binding protein GGA3 /FL=gb:AF219138.1 AF219138 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 GGA3 23163 NM_001172703 /// NM_001172704 /// NM_001291641 /// NM_001291642 /// NM_014001 /// NM_138619 /// NR_033345 /// XM_006721784 /// XM_006721785 /// XR_429878 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 211816_x_at D87858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D87858.1 /DEF=Homo sapiens mRNA for CD89_U04, complete cds. /FEA=CDS /PROD=CD89_U04 /DB_XREF=gi:1561545 /UG=Hs.193122 Fc fragment of IgA, receptor for /FL=gb:D87858.1 gb:D87860.1 D87858 Fc fragment of IgA, receptor for FCAR 2204 NM_002000 /// NM_133269 /// NM_133271 /// NM_133272 /// NM_133273 /// NM_133274 /// NM_133277 /// NM_133278 /// NM_133279 /// NM_133280 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019862 // IgA binding // inferred from electronic annotation 211817_s_at L47208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L47208.1 /DEF=Homo sapiens G protein-activated inwardly rectifying K+ channel (GIRK4) mRNA, complete cds. /FEA=CDS /GEN=GIRK4 /PROD=G protein-activated inwardly rectifying K+channel /DB_XREF=gi:1326052 /UG=Hs.193044 potassium inwardly-rectifying channel, subfamily J, member 5 /FL=gb:L47208.1 L47208 potassium inwardly-rectifying channel, subfamily J, member 5 KCNJ5 3762 NM_000890 /// XM_005271543 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015467 // G-protein activated inward rectifier potassium channel activity // traceable author statement 211818_s_at U88712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U88712.1 /DEF=Human phosphodiesterase 4C mRNA, complete cds. /FEA=CDS /PROD=phosphodiesterase 4C /DB_XREF=gi:1857983 /UG=Hs.189 phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E1) /FL=gb:U88712.1 U88712 uncharacterized LOC729966 /// phosphodiesterase 4C, cAMP-specific LOC729966 /// PDE4C 5143 /// 729966 NM_000923 /// NM_001098818 /// NM_001098819 /// NR_036575 /// NR_040546 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // traceable author statement /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211819_s_at AF136381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF136381.1 /DEF=Homo sapiens c-Cbl-associated protein SH3P12 (SH3P12) mRNA, complete cds. /FEA=CDS /GEN=SH3P12 /PROD=c-Cbl-associated protein SH3P12 /DB_XREF=gi:6651088 /UG=Hs.108924 SH3-domain protein 5 (ponsin) /FL=gb:AF136381.1 AF136381 sorbin and SH3 domain containing 1 SORBS1 10580 NM_001034954 /// NM_001034955 /// NM_001034956 /// NM_001034957 /// NM_001290294 /// NM_001290295 /// NM_001290296 /// NM_001290297 /// NM_001290298 /// NM_006434 /// NM_015385 /// NM_024991 /// XM_005269404 /// XM_005269405 /// XM_005269406 /// XM_005269411 /// XM_005269412 /// XM_005269414 /// XM_005269424 /// XM_005269425 /// XM_005269427 /// XM_005269431 /// XM_005269437 /// XM_005269439 /// XM_005269440 /// XM_006717560 /// XM_006717561 /// XM_006717562 /// XM_006717563 /// XM_006717564 /// XM_006717565 /// XM_006717566 /// XM_006717567 /// XM_006717568 /// XM_006717569 /// XM_006717570 /// XM_006717571 /// XM_006717572 /// XM_006717573 /// XM_006717574 /// XM_006717575 /// XM_006717576 /// XM_006717577 /// XM_006717578 /// XM_006717579 /// XM_006717580 /// XM_006717581 /// XM_006717582 /// XM_006717583 /// XM_006717584 /// XM_006717585 /// XM_006717586 /// XM_006717587 /// XM_006717588 /// XM_006717589 /// XM_006717590 /// XM_006717591 /// XM_006717592 /// XM_006717593 /// XM_006717594 /// XM_006717595 0006810 // transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from sequence or structural similarity /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005899 // insulin receptor complex // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from sequence or structural similarity /// 0005915 // zonula adherens // traceable author statement /// 0005924 // cell-substrate adherens junction // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0003779 // actin binding // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred by curator /// 0005070 // SH3/SH2 adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation 211820_x_at U00179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U00179.1 /DEF=Human glycophorin Erik I-IV (GPErik) mRNA, complete cds. /FEA=CDS /GEN=GPErik /PROD=glycophorin Erik I-IV /DB_XREF=gi:392432 /UG=Hs.108694 glycophorin A (includes MN blood group) /FL=gb:U00179.1 U00179 glycophorin A (MNS blood group) GYPA 2993 NM_002099 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0047484 // regulation of response to osmotic stress // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 211821_x_at U00178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U00178.1 /DEF=Homo sapiens glycophorin Erik STA (GPErik) gene complete cds. /FEA=CDS /GEN=GPErik /PROD=glycophorin Erik (STA) /DB_XREF=gi:392430 /UG=Hs.108694 glycophorin A (includes MN blood group) /FL=gb:U00178.1 U00178 glycophorin A (MNS blood group) GYPA 2993 NM_002099 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0047484 // regulation of response to osmotic stress // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 211822_s_at AF229061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229061.1 /DEF=Homo sapiens NAC-gamma splice variant (NAC) mRNA, complete cds, alternatively spliced. /FEA=CDS /GEN=NAC /PROD=NAC-gamma splice variant /DB_XREF=gi:12656108 /UG=Hs.104305 death effector filament-forming Ced-4-like apoptosis protein /FL=gb:AF229061.1 AF229061 NLR family, pyrin domain containing 1 NLRP1 22861 NM_001033053 /// NM_014922 /// NM_033004 /// NM_033006 /// NM_033007 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051402 // neuron apoptotic process // inferred from direct assay 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072558 // NLRP1 inflammasome complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 211823_s_at D86862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D86862.1 /DEF=Homo sapiens mRNA for paxillin beta, complete cds. /FEA=CDS /PROD=paxillin beta /DB_XREF=gi:1912054 /UG=Hs.102497 paxillin /FL=gb:D86862.1 D86862 paxillin PXN 5829 NM_001080855 /// NM_001243756 /// NM_002859 /// NM_025157 /// XM_005253910 /// XM_005253912 /// XM_005253913 /// XM_005253914 /// XM_005253915 /// XM_005253916 /// XM_005253917 /// XM_006719531 /// XM_006719532 /// XM_006719533 /// XM_006719534 /// XM_006719535 /// XM_006719536 /// XM_006719537 /// XM_006719538 /// XM_006719539 /// XR_243019 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051435 // BH4 domain binding // inferred from electronic annotation 211824_x_at AF229062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229062.1 /DEF=Homo sapiens NAC-delta splice variant (NAC) mRNA, complete cds, alternatively spliced. /FEA=CDS /GEN=NAC /PROD=NAC-delta splice variant /DB_XREF=gi:12656110 /UG=Hs.104305 death effector filament-forming Ced-4-like apoptosis protein /FL=gb:AF229062.1 AF229062 NLR family, pyrin domain containing 1 NLRP1 22861 NM_001033053 /// NM_014922 /// NM_033004 /// NM_033006 /// NM_033007 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051402 // neuron apoptotic process // inferred from direct assay 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072558 // NLRP1 inflammasome complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 211825_s_at AF327066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF327066.1 /DEF=Homo sapiens Ewings sarcoma EWS-Fli1 (type 1) oncogene mRNA, complete cds. /FEA=CDS /PROD=Ewings sarcoma EWS-Fli1 (type 1) oncogene /DB_XREF=gi:12963354 /UG=Hs.129953 Ewing sarcoma breakpoint region 1 /FL=gb:AF327066.1 AF327066 Fli-1 proto-oncogene, ETS transcription factor FLI1 2313 NM_001167681 /// NM_001271010 /// NM_001271012 /// NM_002017 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007599 // hemostasis // traceable author statement /// 0008015 // blood circulation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0035855 // megakaryocyte development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 211826_s_at L22179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L22179.1 /DEF=Human MLL-AF4 der(11) fusion protein mRNA, complete cds. /FEA=CDS /PROD=MLL-AF4 der(11) fusion protein /DB_XREF=gi:347376 /UG=Hs.114765 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 /FL=gb:L22179.1 L22179 AF4/FMR2 family, member 1 AFF1 4299 NM_001166693 /// NM_005935 /// XM_005263007 /// XM_005263008 /// XM_005263009 /// XM_005263010 /// XM_005263011 /// XM_005263012 /// XM_005263013 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211827_s_at AF187964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF187964.1 /DEF=Homo sapiens voltage gated potassium channel Kv4.3 short splice variant (Kv4.3) mRNA, complete cds. /FEA=CDS /GEN=Kv4.3 /PROD=voltage gated potassium channel Kv4.3 shortsplice variant /DB_XREF=gi:6007796 /UG=Hs.184889 potassium voltage-gated channel, Shal-related subfamily, member 3 /FL=gb:AF048712.1 gb:AF187964.1 gb:AF205856.1 AF187964 potassium voltage-gated channel, Shal-related subfamily, member 3 KCND3 3752 NM_004980 /// NM_172198 /// XM_005270851 /// XM_006710629 /// XM_006710630 /// XM_006710631 /// XM_006710632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0086009 // membrane repolarization // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005250 // A-type (transient outward) potassium channel activity // not recorded /// 0005250 // A-type (transient outward) potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211828_s_at AF172268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF172268.1 /DEF=Homo sapiens Traf2 and NCK interacting kinase, splice variant 5 (TNIK) mRNA, complete cds. /FEA=CDS /GEN=TNIK /PROD=Traf2 and NCK interacting kinase, splice variant5 /DB_XREF=gi:6110356 /UG=Hs.170204 KIAA0551 protein /FL=gb:AF172268.1 AF172268 TRAF2 and NCK interacting kinase TNIK 23043 NM_001161560 /// NM_001161561 /// NM_001161562 /// NM_001161563 /// NM_001161564 /// NM_001161565 /// NM_001161566 /// NM_015028 /// NR_027767 /// XM_006713555 0006468 // protein phosphorylation // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007256 // activation of JNKK activity // inferred from direct assay /// 0007256 // activation of JNKK activity // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211829_s_at U58828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U58828.1 /DEF=Human IL8-related receptor (DRY12) mRNA, complete cds. /FEA=CDS /GEN=DRY12 /PROD=IL8-related receptor /DB_XREF=gi:1381668 /UG=Hs.113207 G protein-coupled receptor 30 /FL=gb:U58828.1 U58828 G protein-coupled estrogen receptor 1 GPER1 2852 NM_001031682 /// NM_001039966 /// NM_001098201 /// NM_001505 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001956 // positive regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002695 // negative regulation of leukocyte activation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from sequence or structural similarity /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031959 // mineralocorticoid receptor signaling pathway // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051053 // negative regulation of DNA metabolic process // inferred from sequence or structural similarity /// 0051055 // negative regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from direct assay /// 0071389 // cellular response to mineralocorticoid stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0032591 // dendritic spine membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0043679 // axon terminus // inferred from sequence or structural similarity /// 0044327 // dendritic spine head // inferred from sequence or structural similarity /// 0045095 // keratin filament // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048786 // presynaptic active zone // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017082 // mineralocorticoid receptor activity // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay 211830_s_at AF211189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF211189.1 /DEF=Homo sapiens T-type calcium channel alpha1 subunit Alpha1I-a isoform (CACNA1I) mRNA, complete cds. /FEA=CDS /GEN=CACNA1I /PROD=T-type calcium channel alpha1 subunit Alpha1I-aisoform /DB_XREF=gi:7271790 /UG=Hs.125116 calcium channel, voltage-dependent, alpha 1I subunit /FL=gb:AF211189.1 AF211189 calcium channel, voltage-dependent, T type, alpha 1I subunit CACNA1I 8911 NM_001003406 /// NM_021096 /// XM_006724348 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030317 // sperm motility // not recorded /// 0030431 // sleep // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008332 // low voltage-gated calcium channel activity // non-traceable author statement 211831_s_at U59495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U59495.1 /DEF=Human truncated thrombopoietin (thTPO) mRNA, complete cds. /FEA=CDS /GEN=thTPO /PROD=truncated thrombopoietin /DB_XREF=gi:1401249 /UG=Hs.1166 thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) /FL=gb:U59495.1 U59495 thrombopoietin THPO 7066 NM_000460 /// NM_001177597 /// NM_001177598 /// NM_001289997 /// NM_001289998 /// NM_001290003 /// NM_001290022 /// NM_001290026 /// NM_001290027 /// NM_001290028 /// NM_199228 /// NM_199356 /// XM_005247737 /// XM_006713738 /// XM_006713739 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0038163 // thrombopoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0008083 // growth factor activity // traceable author statement 211832_s_at AF201370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201370.1 /DEF=Homo sapiens MDM2-a1 mRNA, complete cds. /FEA=CDS /PROD=MDM2-a1 /DB_XREF=gi:7230489 /UG=Hs.170027 mouse double minute 2, human homolog of; p53-binding protein /FL=gb:AF201370.1 AF201370 MDM2 proto-oncogene, E3 ubiquitin protein ligase MDM2 4193 NM_001145336 /// NM_001145337 /// NM_001145339 /// NM_001145340 /// NM_001278462 /// NM_002392 /// NM_006878 /// NM_006879 /// NM_006880 /// NM_006881 /// NM_006882 /// NM_032739 /// XM_005268872 /// XM_006719399 /// XM_006719400 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018205 // peptidyl-lysine modification // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071301 // cellular response to vitamin B1 // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071494 // cellular response to UV-C // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 211833_s_at U19599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U19599.1 /DEF=Human (BAX delta) mRNA, complete cds. /FEA=CDS /PROD=BAX delta /DB_XREF=gi:841237 /UG=Hs.159428 BCL2-associated X protein /FL=gb:U19599.1 U19599 BCL2-associated X protein BAX 581 NM_001291428 /// NM_001291429 /// NM_001291430 /// NM_001291431 /// NM_004324 /// NM_138761 /// NM_138762 /// NM_138763 /// NM_138764 /// NR_027882 /// XM_006723313 /// XM_006723314 0001101 // response to acid // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001777 // T cell homeostatic proliferation // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from direct assay /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0001844 // protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0002352 // B cell negative selection // inferred from electronic annotation /// 0002358 // B cell homeostatic proliferation // inferred from electronic annotation /// 0002904 // positive regulation of B cell apoptotic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006927 // transformed cell apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred by curator /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0009566 // fertilization // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010248 // establishment or maintenance of transmembrane electrochemical gradient // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from electronic annotation /// 0032976 // release of matrix enzymes from mitochondria // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from physical interaction /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0046666 // retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048515 // spermatid differentiation // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation /// 1902263 // apoptotic process involved in embryonic digit morphogenesis // inferred from electronic annotation /// 1902512 // positive regulation of apoptotic DNA fragmentation // inferred from mutant phenotype /// 1990009 // retinal cell apoptotic process // inferred from mutant phenotype /// 1990117 // B cell receptor apoptotic signaling pathway // inferred from direct assay /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005757 // mitochondrial permeability transition pore complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097136 // Bcl-2 family protein complex // inferred from direct assay /// 0097144 // BAX complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0015267 // channel activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from direct assay /// 0051434 // BH3 domain binding // inferred from physical interaction 211834_s_at AB042841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042841.1 /DEF=Homo sapiens p73Lp63p51p40KET mRNA for delta N p73L, complete cds. /FEA=CDS /GEN=p73Lp63p51p40KET /PROD=delta N p73L /DB_XREF=gi:12060405 /UG=Hs.137569 tumor protein 63 kDa with strong homology to p53 /FL=gb:AB042841.1 AB042841 tumor protein p63 TP63 8626 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982 /// NM_003722 /// XM_005247843 /// XM_005247844 /// XM_005247846 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001738 // morphogenesis of a polarized epithelium // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007499 // ectoderm and mesoderm interaction // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0010481 // epidermal cell division // inferred from electronic annotation /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0030859 // polarized epithelial cell differentiation // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0034644 // cellular response to UV // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // not recorded /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045617 // negative regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060197 // cloacal septation // inferred from electronic annotation /// 0060513 // prostatic bud formation // inferred from electronic annotation /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 1902808 // positive regulation of cell cycle G1/S phase transition // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2000381 // negative regulation of mesoderm development // inferred from electronic annotation /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0030425 // dendrite // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 211835_at AJ225093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AJ225093.1 /DEF=Homo sapiens mRNA for single-chain antibody, complete cds (scFv2). /FEA=CDS /PROD=immunoglobulin /DB_XREF=gi:3090427 /UG=Hs.159386 Homo sapiens mRNA for single-chain antibody, complete cds (scFv2) /FL=gb:AJ225093.1 AJ225093 immunoglobulin kappa constant /// /// immunoglobulin kappa variable 1-5 /// Homo sapiens clone 135b08 anti-tetanus toxoid immunoglobulin light chain variable region (IGL@) mRNA, partial cds. IGKC /// IGKV1-5 /// IGKV1-5 /// IGL@ 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211836_s_at U18800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U18800.1 /DEF=Human myelinoligodendrocyte glycoprotein MOG alpha 4 isoform (MOG) mRNA, complete cds. /FEA=CDS /GEN=MOG /PROD=myelinoligodendrocyte glycoprotein alpha 4isoform /DB_XREF=gi:1688058 /UG=Hs.141308 myelin oligodendrocyte glycoprotein /FL=gb:U18800.1 U18800 myelin oligodendrocyte glycoprotein MOG 4340 NM_001008228 /// NM_001008229 /// NM_001170418 /// NM_002433 /// NM_206809 /// NM_206810 /// NM_206811 /// NM_206812 /// NM_206813 /// NM_206814 /// XM_005249131 /// XM_005249139 /// XM_005249140 /// XM_005272820 /// XM_005272829 /// XM_005272830 /// XM_005274865 /// XM_005274874 /// XM_005274875 /// XM_005274977 /// XM_005274986 /// XM_005275125 /// XM_005275134 /// XM_005275252 /// XM_005275261 /// XM_005275262 /// XM_005275410 /// XM_005275419 /// XM_005275558 /// XM_005275567 /// XM_005275568 0007155 // cell adhesion // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0034126 // positive regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211837_s_at AF165312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF165312.1 /DEF=Homo sapiens pre-T-cell receptor alpha chain (PTA) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=PTA /PROD=pre-T-cell receptor alpha chain /DB_XREF=gi:9621867 /UG=Hs.169002 Human pre TCR alpha mRNA, partial cds /FL=gb:AF165312.1 AF165312 pre T-cell antigen receptor alpha PTCRA 171558 NM_001243168 /// NM_001243169 /// NM_001243170 /// NM_138296 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211838_x_at AF152483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152483.1 /DEF=Homo sapiens protocadherin alpha 5 short form protein (PCDH-alpha5) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-alpha5 /PROD=protocadherin alpha 5 short form protein /DB_XREF=gi:5457014 /UG=Hs.167399 protocadherin alpha 5 /FL=gb:AF152483.1 AF152483 protocadherin alpha 5 PCDHA5 56143 NM_018908 /// NM_031501 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 211839_s_at U22386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U22386.1 /DEF=Human macrophage-colony stimulating factor gamma precursor mRNA, complete cds. /FEA=CDS /PROD=macrophage-colony stimulating factor gammaprecursor /DB_XREF=gi:758780 /UG=Hs.173894 colony stimulating factor 1 (macrophage) /FL=gb:U22386.1 U22386 colony stimulating factor 1 (macrophage) CSF1 1435 NM_000757 /// NM_172210 /// NM_172211 /// NM_172212 0001503 // ossification // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0003006 // developmental process involved in reproduction // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010743 // regulation of macrophage derived foam cell differentiation // non-traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0030097 // hemopoiesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032946 // positive regulation of mononuclear cell proliferation // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042117 // monocyte activation // non-traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042488 // positive regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060611 // mammary gland fat development // inferred from electronic annotation /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay /// 0005157 // macrophage colony-stimulating factor receptor binding // inferred from sequence or structural similarity /// 0005157 // macrophage colony-stimulating factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 211840_s_at U50157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U50157.1 /DEF=Human cAMP-specific phosphodiesterase HPDE4D1 variant (PDE4D) mRNA, complete cds. /FEA=CDS /GEN=PDE4D /PROD=cAMP-specific phosphodiesterase HPDE4D1 variant /DB_XREF=gi:1236954 /UG=Hs.172081 phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) /FL=gb:U50157.1 U50157 phosphodiesterase 4D, cAMP-specific PDE4D 5144 NM_001104631 /// NM_001165899 /// NM_001197218 /// NM_001197219 /// NM_001197220 /// NM_001197221 /// NM_001197222 /// NM_001197223 /// NM_006203 /// XM_005248537 /// XM_005248538 /// XM_005248540 /// XM_005248541 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0010469 // regulation of receptor activity // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0032754 // positive regulation of interleukin-5 production // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 0086024 // adrenergic receptor signaling pathway involved in positive regulation of heart rate // inferred by curator /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0030552 // cAMP binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 211841_s_at U94510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U94510.1 /DEF=Human lymphocyte associated receptor of death 9 mRNA, alternatively spliced, complete cds. /FEA=CDS /PROD=lymphocyte associated receptor of death 9 /DB_XREF=gi:2071966 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) /FL=gb:U94510.1 U94510 tumor necrosis factor receptor superfamily, member 25 TNFRSF25 8718 NM_001039664 /// NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148974 0006915 // apoptotic process // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 211842_s_at AF026132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF026132.1 /DEF=Homo sapiens retinal rod Na+Ca+, K+ exchanger (NCKX) mRNA, complete cds. /FEA=CDS /GEN=NCKX /PROD=retinal rod Na+Ca+, K+ exchanger /DB_XREF=gi:2811134 /UG=Hs.173092 solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 1 /FL=gb:AF026132.1 AF026132 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 SLC24A1 9187 NM_001254740 /// NM_004727 /// XM_005254778 /// XM_005254779 /// XM_005254780 /// XM_005254781 /// XM_006720764 /// XM_006720765 /// XM_006720766 /// XM_006720767 /// XM_006720768 /// XM_006720769 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007601 // visual perception // non-traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009642 // response to light intensity // non-traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019867 // outer membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008273 // calcium, potassium:sodium antiporter activity // non-traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 211843_x_at AF315325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF315325.1 /DEF=Homo sapiens cytochrome P450 variant 3A7 (CYP3A7) mRNA, complete cds. /FEA=CDS /GEN=CYP3A7 /PROD=cytochrome P450 variant 3A7 /DB_XREF=gi:12082808 /UG=Hs.172323 cytochrome P450, subfamily IIIA, polypeptide 7 /FL=gb:AF315325.1 AF315325 CYP3A7-CYP3AP1 readthrough CYP3A7-CYP3AP1 100861540 NM_001256497 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 211844_s_at AF022859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF022859.1 /DEF=Homo sapiens neuropilin-2(a0) mRNA, complete cds. /FEA=CDS /PROD=neuropilin-2(a0) /DB_XREF=gi:2547129 /UG=Hs.17778 neuropilin 2 /FL=gb:AF022859.1 AF022859 neuropilin 2 NRP2 8828 NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934 0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 211845_at AF110314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF110314.1 /DEF=Homo sapiens herpesvirus immunoglobulin-like receptor HIgR mRNA, complete cds. /FEA=CDS /PROD=herpesvirus immunoglobulin-like receptor HIgR /DB_XREF=gi:4154345 /UG=Hs.179999 poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) /FL=gb:AF110314.1 AF110314 poliovirus receptor-related 1 (herpesvirus entry mediator C) PVRL1 5818 NM_002855 /// NM_032767 /// NM_203285 /// NM_203286 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002934 // desmosome organization // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0046718 // viral entry into host cell // non-traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // non-traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046790 // virion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 211846_s_at AF110314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF110314.1 /DEF=Homo sapiens herpesvirus immunoglobulin-like receptor HIgR mRNA, complete cds. /FEA=CDS /PROD=herpesvirus immunoglobulin-like receptor HIgR /DB_XREF=gi:4154345 /UG=Hs.179999 poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) /FL=gb:AF110314.1 AF110314 poliovirus receptor-related 1 (herpesvirus entry mediator C) PVRL1 5818 NM_002855 /// NM_032767 /// NM_203285 /// NM_203286 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002934 // desmosome organization // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0046718 // viral entry into host cell // non-traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051963 // regulation of synapse assembly // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070166 // enamel mineralization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // non-traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046790 // virion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 211848_s_at AF006623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF006623.1 /DEF=Homo sapiens carcinoembryonic antigen 2b (CGM2) mRNA, complete cds. /FEA=CDS /GEN=CGM2 /PROD=carcinoembryonic antigen 2b /DB_XREF=gi:2253375 /UG=Hs.74466 carcinoembryonic antigen-related cell adhesion molecule 7 /FL=gb:AF006623.1 AF006623 carcinoembryonic antigen-related cell adhesion molecule 7 CEACAM7 1087 NM_001291485 /// NM_006890 /// XM_005258430 /// XM_005278379 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 211849_s_at AB009023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB009023.1 /DEF=Homo sapiens HCE1A mRNA for capping enzyme 1A, complete cds. /FEA=CDS /GEN=HCE1A /PROD=capping enzyme 1A /DB_XREF=gi:3097309 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AB009023.1 gb:AB009024.1 AB009023 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 211851_x_at AF005068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF005068.1 /DEF=Homo sapiens breast and ovarian cancer susceptibility protein splice variant (BRCA1) mRNA, complete cds. /FEA=CDS /GEN=BRCA1 /PROD=breast and ovarian cancer susceptibility proteinsplice variant /DB_XREF=gi:2218153 /UG=Hs.194143 breast cancer 1, early onset /FL=gb:AF005068.1 AF005068 breast cancer 1, early onset BRCA1 672 NM_007294 /// NM_007295 /// NM_007296 /// NM_007297 /// NM_007298 /// NM_007299 /// NM_007300 /// NM_007301 /// NM_007302 /// NM_007303 /// NM_007305 /// NM_007306 /// NR_027676 /// XM_006722029 /// XM_006722030 /// XM_006722031 /// XM_006722032 /// XM_006722033 /// XM_006722034 /// XM_006722035 /// XM_006722036 /// XM_006722037 /// XM_006722038 /// XM_006722039 /// XM_006722040 /// XM_006722041 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043009 // chordate embryonic development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0044030 // regulation of DNA methylation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046600 // negative regulation of centriole replication // non-traceable author statement /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from direct assay /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070512 // positive regulation of histone H4-K20 methylation // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay /// 2000145 // regulation of cell motility // inferred from direct assay /// 2000617 // positive regulation of histone H3-K9 acetylation // inferred from direct assay /// 2000620 // positive regulation of histone H4-K16 acetylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008274 // gamma-tubulin ring complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031436 // BRCA1-BARD1 complex // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015631 // tubulin binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 211852_s_at AF106861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF106861.1 /DEF=Homo sapiens attractin-2 (ATRN) mRNA, complete cds. /FEA=CDS /GEN=ATRN /PROD=attractin-2 /DB_XREF=gi:4093195 /UG=Hs.194019 attractin /FL=gb:AF106861.1 AF106861 attractin ATRN 8455 NM_001207047 /// NM_012070 /// NM_139321 /// NM_139322 /// XM_005260860 /// XM_005260861 0006954 // inflammatory response // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 211855_s_at AF155810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF155810.1 /DEF=Homo sapiens mitochondrial uncoupling protein 5 short form with insertion mRNA, complete cds; nuclear gene for mitochondrial product. /FEA=CDS /PROD=mitochondrial uncoupling protein 5 short formwith insertion /DB_XREF=gi:11094336 /UG=Hs.194686 solute carrier family 25 (mitochondrial carrier, brain), member 14 /FL=gb:AF155810.1 AF155810 solute carrier family 25 (mitochondrial carrier, brain), member 14 SLC25A14 9016 NM_001282195 /// NM_001282196 /// NM_001282197 /// NM_001282198 /// NM_003951 /// NM_022810 /// NR_104107 /// XM_005262485 /// XM_005262488 /// XM_005262489 /// XM_006724786 /// XM_006724787 /// XM_006724788 /// XM_006724789 /// XR_244526 /// XR_430549 /// XR_430550 0006810 // transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 211856_x_at AF222341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF222341.1 /DEF=Homo sapiens T-cell specific surface glycoprotein CD28 isoform 1 (CD28) gene, complete cds. /FEA=CDS /GEN=CD28 /PROD=T-cell specific surface glycoprotein CD28isoform 1 /DB_XREF=gi:6969512 /UG=Hs.1987 CD28 antigen (Tp44) /FL=gb:AF222341.1 AF222341 CD28 molecule CD28 940 NM_001243077 /// NM_001243078 /// NM_006139 /// XM_006712862 0002863 // positive regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042089 // cytokine biosynthetic process // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // traceable author statement /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045066 // regulatory T cell differentiation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // non-traceable author statement /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0042802 // identical protein binding // non-traceable author statement 211858_x_at AF088184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF088184.1 /DEF=Homo sapiens guanine nucleotide-binding protein Gs alpha subunit isoform L2 mRNA, complete cds. /FEA=CDS /PROD=guanine nucleotide-binding protein Gs alphasubunit isoform L2 /DB_XREF=gi:3552031 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 /FL=gb:AF088184.1 AF088184 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 211861_x_at AF222343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF222343.1 /DEF=Homo sapiens T-cell specific surface glycoprotein CD28 isoform 3 (CD28) gene, complete cds. /FEA=CDS /GEN=CD28 /PROD=T-cell specific surface glycoprotein CD28isoform 3 /DB_XREF=gi:6969516 /UG=Hs.1987 CD28 antigen (Tp44) /FL=gb:AF222343.1 AF222343 CD28 molecule CD28 940 NM_001243077 /// NM_001243078 /// NM_006139 /// XM_006712862 0002863 // positive regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042089 // cytokine biosynthetic process // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // traceable author statement /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045066 // regulatory T cell differentiation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // non-traceable author statement /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // non-traceable author statement /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0042802 // identical protein binding // non-traceable author statement 211862_x_at AF015451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF015451.1 /DEF=Homo sapiens Usurpin-beta mRNA, complete cds. /FEA=CDS /PROD=Usurpin-beta /DB_XREF=gi:3133282 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF015451.1 AF015451 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 211863_x_at AF079408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF079408.1 /DEF=Homo sapiens hemochromatosis splice variant delE2 (HFE) mRNA, complete cds. /FEA=CDS /GEN=HFE /PROD=hemochromatosis splice variant delE2 /DB_XREF=gi:3695108 /UG=Hs.20019 hemochromatosis /FL=gb:AF079408.1 AF079408 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211864_s_at AF207990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF207990.1 /DEF=Homo sapiens fer-1 like protein 3 (FER1L3) mRNA, complete cds. /FEA=CDS /GEN=FER1L3 /PROD=fer-1 like protein 3 /DB_XREF=gi:10834586 /UG=Hs.234680 fer-1 (C.elegans)-like 3 (myoferlin) /FL=gb:AF207990.1 AF207990 myoferlin MYOF 26509 NM_013451 /// NM_133337 /// XM_005269693 /// XM_005269694 /// XM_006717760 0001778 // plasma membrane repair // inferred from sequence or structural similarity /// 0006936 // muscle contraction // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from sequence or structural similarity 211865_s_at AB013463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB013463.1 /DEF=Homo sapiens mRNA for Fzr2, complete cds. /FEA=CDS /GEN=fzr2 /PROD=Fzr2 /DB_XREF=gi:6463684 /UG=Hs.268384 Fzr1 protein /FL=gb:AB013463.1 AB013463 fizzy/cell division cycle 20 related 1 (Drosophila) FZR1 51343 NM_001136197 /// NM_001136198 /// NM_016263 /// XM_005259573 /// XM_006722764 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // traceable author statement /// 0090344 // negative regulation of cell aging // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211866_x_at AF079409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF079409.1 /DEF=Homo sapiens Hemochromatosis splice variant delE2(14E4) (HFE) mRNA, complete cds. /FEA=CDS /GEN=HFE /PROD=hemochromatosis splice variant delE214E4 /DB_XREF=gi:3695110 /UG=Hs.20019 hemochromatosis /FL=gb:AF079409.1 AF079409 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 211867_s_at AF152475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152475.1 /DEF=Homo sapiens protocadherin alpha 10 short form protein (PCDH-alpha10) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-alpha10 /PROD=protocadherin alpha 10 short form protein /DB_XREF=gi:5456992 /UG=Hs.247735 protocadherin alpha 10 /FL=gb:AF152475.1 AF152475 protocadherin alpha 10 PCDHA10 56139 NM_018901 /// NM_031859 /// NM_031860 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 211868_x_at AJ225092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AJ225092.1 /DEF=Homo sapiens mRNA for single-chain antibody, complete cds. /FEA=CDS /PROD=immunoglobulin /DB_XREF=gi:3090425 /UG=Hs.249245 Homo sapiens mRNA for single-chain antibody, complete cds /FL=gb:AJ225092.1 AJ225092 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG2 /// IGHG3 /// IGHM /// IGHV4-31 3492 /// 3493 /// 3494 /// 3495 /// 3500 /// 3501 /// 3502 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 211869_at AF049656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF049656.1 /DEF=Homo sapiens inducible nitric oxide synthase (iNOS) mRNA, complete cds. /FEA=CDS /GEN=iNOS /PROD=inducible nitric oxide synthase /DB_XREF=gi:2935552 /UG=Hs.248084 Homo sapiens inducible nitric oxide synthase (iNOS) mRNA, complete cds /FL=gb:AF049656.1 gb:AF051164.1 AF049656 0001935 // endothelial cell proliferation // inferred from expression pattern /// 0001974 // blood vessel remodeling // inferred from mutant phenotype /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006954 // inflammatory response // /// 0007165 // signal transduction // inferred from direct assay /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // /// 0007568 // aging // inferred from expression pattern /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0009725 // response to hormone // inferred from expression pattern /// 0014823 // response to activity // inferred from expression pattern /// 0016137 // glycoside metabolic process // inferred from expression pattern /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0031284 // positive regulation of guanylate cyclase activity // /// 0032355 // response to estradiol // inferred from expression pattern /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035902 // response to immobilization stress // inferred from expression pattern /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045776 // negative regulation of blood pressure // /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045909 // positive regulation of vasodilation // /// 0048384 // retinoic acid receptor signaling pathway // inferred from expression pattern /// 0050829 // defense response to Gram-negative bacterium // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from expression pattern /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071461 // cellular response to redox state // inferred from expression pattern /// 0071548 // response to dexamethasone // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // /// 0005829 // cytosol // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0003958 // NADPH-hemoprotein reductase activity // /// 0004517 // nitric-oxide synthase activity // inferred from direct assay /// 0004517 // nitric-oxide synthase activity // inferred from electronic annotation /// 0004517 // nitric-oxide synthase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0010181 // FMN binding // inferred from electronic annotation /// 0010181 // FMN binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0045296 // cadherin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050661 // NADP binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // inferred from direct assay 211870_s_at AF152481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152481.1 /DEF=Homo sapiens protocadherin alpha 3 short form protein (PCDH-alpha3) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-alpha3 /PROD=protocadherin alpha 3 short form protein /DB_XREF=gi:5457010 /UG=Hs.247740 protocadherin alpha 3 /FL=gb:AF152481.1 AF152481 protocadherin alpha 2 /// protocadherin alpha 3 PCDHA2 /// PCDHA3 56145 /// 56146 NM_018905 /// NM_018906 /// NM_031495 /// NM_031496 /// NM_031497 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 211871_x_at AF300650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF300650.1 /DEF=Homo sapiens guanine nucleotide binding protein beta subunit 5L (GNB5) mRNA, complete cds. /FEA=CDS /GEN=GNB5 /PROD=guanine nucleotide binding protein beta subunit5L /DB_XREF=gi:10505351 /UG=Hs.275353 guanine nucleotide binding protein (G protein), beta 5 /FL=gb:AF300650.1 AF300650 guanine nucleotide binding protein (G protein), beta 5 GNB5 10681 NM_006578 /// NM_016194 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031682 // G-protein gamma-subunit binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 211872_s_at AB016929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016929.1 /DEF=Homo sapiens RGS11 mRNA for regulator of G-protein signaling 11, complete cds. /FEA=CDS /GEN=RGS11 /PROD=regulator of G-protein signaling 11 /DB_XREF=gi:4239943 /UG=Hs.65756 regulator of G-protein signalling 11 /FL=gb:AB016929.1 AB016929 regulator of G-protein signaling 11 RGS11 8786 NM_001286485 /// NM_001286486 /// NM_003834 /// NM_183337 /// XR_429649 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0044292 // dendrite terminus // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0031681 // G-protein beta-subunit binding // inferred from physical interaction 211873_s_at AF152516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152516.1 /DEF=Homo sapiens protocadherin gamma A9 short form protein (PCDH-gamma-A9) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-A9 /PROD=protocadherin gamma A9 short form protein /DB_XREF=gi:5457079 /UG=Hs.283796 protocadherin gamma subfamily A, 9 /FL=gb:AF152516.1 AF152516 protocadherin gamma subfamily A, 9 PCDHGA9 56107 NM_018921 /// NM_032089 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211874_s_at AF119230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119230.1 /DEF=Homo sapiens histone acetyltransferase MORF alpha mRNA, alternative splice product, complete cds. /FEA=CDS /PROD=histone acetyltransferase MORF alpha /DB_XREF=gi:6002693 /UG=Hs.27590 histone acetyltransferase /FL=gb:AF119230.1 AF119230 K(lysine) acetyltransferase 6B KAT6B 23522 NM_001256468 /// NM_001256469 /// NM_012330 /// XM_005269664 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211875_x_at AF152503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152503.1 /DEF=Homo sapiens protocadherin gamma A10 short form protein (PCDH-gamma-A10) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-A10 /PROD=protocadherin gamma A10 short form protein /DB_XREF=gi:5457054 /UG=Hs.283795 protocadherin gamma subfamily A, 10 /FL=gb:AF152503.1 AF152503 protocadherin gamma subfamily A, 10 PCDHGA10 56106 NM_018913 /// NM_032090 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211876_x_at AF152504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152504.1 /DEF=Homo sapiens protocadherin gamma A11 (PCDH-gamma-A11) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=PCDH-gamma-A11 /PROD=protocadherin gamma A11 /DB_XREF=gi:5457056 /UG=Hs.283794 protocadherin gamma subfamily A, 11 /FL=gb:AF152504.1 AF152504 protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily C, 3 PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA3 /// PCDHGA5 /// PCDHGA6 /// PCDHGC3 5098 /// 26025 /// 56105 /// 56106 /// 56109 /// 56110 /// 56112 NM_002588 /// NM_003735 /// NM_018913 /// NM_018914 /// NM_018916 /// NM_018918 /// NM_018919 /// NM_032011 /// NM_032054 /// NM_032086 /// NM_032090 /// NM_032091 /// NM_032092 /// NM_032094 /// NM_032402 /// NM_032403 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211877_s_at AF152505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152505.1 /DEF=Homo sapiens protocadherin gamma A11 short form protein (PCDH-gamma-A11) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-A11 /PROD=protocadherin gamma A11 short form protein /DB_XREF=gi:5457058 /UG=Hs.283794 protocadherin gamma subfamily A, 11 /FL=gb:AF152505.1 AF152505 protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily C, 3 PCDHGA11 /// PCDHGC3 5098 /// 56105 NM_002588 /// NM_018914 /// NM_032091 /// NM_032092 /// NM_032402 /// NM_032403 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211878_at M26463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M26463.1 /DEF=Homo sapiens immunoglobulin mu chain antibody MO30 (IgM) mRNA, complete cds. /FEA=CDS /GEN=IgM /PROD=immunoglobulin mu chain antibody MO30 /DB_XREF=gi:619757 /UG=Hs.284277 Homo sapiens immunoglobulin mu chain antibody MO30 (IgM) mRNA, complete cds /FL=gb:M26463.1 M26463 211879_x_at AF152510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152510.1 /DEF=Homo sapiens protocadherin gamma A3 short form protein (PCDH-gamma-A3) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-A3 /PROD=protocadherin gamma A3 short form protein /DB_XREF=gi:5457067 /UG=Hs.283800 protocadherin gamma subfamily A, 3 /FL=gb:AF152510.1 AF152510 protocadherin gamma subfamily A, 3 PCDHGA3 56112 NM_018916 /// NM_032011 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211880_x_at AF152507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF152507.1 /DEF=Homo sapiens protocadherin gamma A1 short form protein (PCDH-gamma-A1) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-A1 /PROD=protocadherin gamma A1 short form protein /DB_XREF=gi:5457062 /UG=Hs.284180 protocadherin gamma subfamily A, 1 /FL=gb:AF152507.1 AF152507 protocadherin gamma subfamily A, 1 PCDHGA1 56114 NM_018912 /// NM_031993 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211881_x_at AB014341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014341.1 /DEF=Homo sapiens mRNA for VEGF single chain antibody, complete cds. /FEA=CDS /PROD=VEGF single chain antibody /DB_XREF=gi:3150270 /UG=Hs.289110 immunoglobulin lambda joining 3 /FL=gb:AB014341.1 AB014341 immunoglobulin lambda joining 3 IGLJ3 28831 211882_x_at U27331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27331.1 /DEF=Human alpha (1,3) fucosyltransferase (FUT6) mRNA, isoform I, complete cds. /FEA=CDS /GEN=FUT6 /PROD=alpha (1,3) fucosyltransferase /DB_XREF=gi:967198 /UG=Hs.32956 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) /FL=gb:U27331.1 U27331 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) FUT6 2528 NM_000150 /// NM_001040701 /// XM_005259526 /// XM_005259527 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 211883_x_at M76742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M76742.1 /DEF=Homo sapiens alternatively spliced biliary glycoprotein (BGPa) mRNA, complete cds. /FEA=CDS /GEN=BGPa /PROD=biliary glycoprotein /DB_XREF=gi:179480 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:M76742.1 M76742 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) CEACAM1 634 NM_001024912 /// NM_001184813 /// NM_001184815 /// NM_001184816 /// NM_001205344 /// NM_001712 0001525 // angiogenesis // non-traceable author statement /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 211884_s_at U31931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U31931.1 /DEF=Human class II MHC mutant RJ2.2.5 mRNA, allele CIITA, complete cds. /FEA=CDS /PROD=class II MHC mutant RJ2.2.5 /DB_XREF=gi:1143159 /UG=Hs.3076 MHC class II transactivator /FL=gb:U31931.1 U31931 class II, major histocompatibility complex, transactivator CIITA 4261 NM_000246 /// NM_001286402 /// NM_001286403 /// NR_104444 /// XM_005255320 /// XM_005255321 /// XM_005255323 /// XM_006720880 /// XM_006720881 /// XM_006720882 /// XM_006720883 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032966 // negative regulation of collagen biosynthetic process // inferred by curator /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0045345 // positive regulation of MHC class I biosynthetic process // inferred from direct assay /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from electronic annotation /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 211885_x_at U27332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U27332.1 /DEF=Human alpha (1,3) fucosyltransferase (FUT6) mRNA, isoform II, complete cds. /FEA=CDS /GEN=FUT6 /PROD=alpha (1,3) fucosyltransferase /DB_XREF=gi:967200 /UG=Hs.32956 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) /FL=gb:U27332.1 U27332 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) FUT6 2528 NM_000150 /// NM_001040701 /// XM_005259526 /// XM_005259527 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 211886_s_at U80987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U80987.1 /DEF=Human transcription factor TBX5 mRNA, complete cds. /FEA=CDS /GEN=TBX5 /PROD=transcription factor TBX5 /DB_XREF=gi:2281318 /UG=Hs.50947 T-box 5 /FL=gb:U80987.1 U80987 T-box 5 TBX5 6910 NM_000192 /// NM_080717 /// NM_080718 /// NM_181486 /// XM_006719582 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003218 // cardiac left ventricle formation // inferred from sequence or structural similarity /// 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0003283 // atrial septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from direct assay /// 0007507 // heart development // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010719 // negative regulation of epithelial to mesenchymal transition // traceable author statement /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060039 // pericardium development // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from direct assay /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060980 // cell migration involved in coronary vasculogenesis // traceable author statement /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 1900117 // regulation of execution phase of apoptosis // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 211887_x_at AF037351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037351.1 /DEF=Homo sapiens macrophage scavenger receptor type III (SR-A) mRNA, complete cds. /FEA=CDS /GEN=SR-A /PROD=macrophage scavenger receptor type III /DB_XREF=gi:3004959 /UG=Hs.49 macrophage scavenger receptor 1 /FL=gb:AF037351.1 AF037351 macrophage scavenger receptor 1 MSR1 4481 NM_002445 /// NM_138715 /// NM_138716 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042221 // response to chemical // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from sequence or structural similarity 211888_x_at AF111345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF111345.1 /DEF=Homo sapiens caspase-10d mRNA, complete cds. /FEA=CDS /PROD=caspase-10d /DB_XREF=gi:4731238 /UG=Hs.5353 caspase 10, apoptosis-related cysteine protease /FL=gb:AF111345.1 AF111345 caspase 10, apoptosis-related cysteine peptidase CASP10 843 NM_001206524 /// NM_001206542 /// NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 /// XM_005246907 /// XM_005246909 /// XM_005246910 /// XM_005246911 /// XM_006712796 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from reviewed computational analysis /// 0045087 // innate immune response // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0097342 // ripoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 211889_x_at D12502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D12502.1 /DEF=Human mRNA for biliary glycoprotein, complete cds. /FEA=CDS /GEN=BGP /PROD=biliary glycoprotein /DB_XREF=gi:219494 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:D12502.1 D12502 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) CEACAM1 634 NM_001024912 /// NM_001184813 /// NM_001184815 /// NM_001184816 /// NM_001205344 /// NM_001712 0001525 // angiogenesis // non-traceable author statement /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016477 // cell migration // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 211890_x_at AF127765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF127765.3 /DEF=Homo sapiens calpain 3 (CAPN3) mRNA, complete cds, alternatively spliced. /FEA=CDS /GEN=CAPN3 /PROD=calpain 3 /DB_XREF=gi:7684606 /UG=Hs.40300 calpain 3, (p94) /FL=gb:AF127765.3 AF127765 calpain 3, (p94) CAPN3 825 NM_000070 /// NM_024344 /// NM_173087 /// NM_173088 /// NM_173089 /// NM_173090 /// NM_212465 /// NR_027911 /// NR_027912 0001896 // autolysis // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0014718 // positive regulation of satellite cell activation involved in skeletal muscle regeneration // inferred from sequence or structural similarity /// 0014850 // response to muscle activity // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // traceable author statement /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0045661 // regulation of myoblast differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0061061 // muscle structure development // inferred from sequence or structural similarity /// 0070315 // G1 to G0 transition involved in cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071472 // cellular response to salt stress // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0008307 // structural constituent of muscle // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from sequence or structural similarity /// 0031432 // titin binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055103 // ligase regulator activity // inferred from direct assay 211891_s_at AB042199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042199.1 /DEF=Homo sapiens Asef mRNA for APC-stimulated guanine nucleotide exchange factor, complete cds. /FEA=CDS /GEN=Asef /PROD=APC-stimulated guanine nucleotide exchangefactor /DB_XREF=gi:9857317 /UG=Hs.6066 Rho guanine nucleotide exchange factor (GEF) 4 /FL=gb:AB042199.1 AB042199 Rho guanine nucleotide exchange factor (GEF) 4 /// rho guanine nucleotide exchange factor 4-like ARHGEF4 /// LOC101930241 50649 /// 101930241 NM_015320 /// NM_032995 /// XM_005263681 /// XM_005263682 /// XM_005263683 /// XM_005263685 /// XM_005263686 /// XM_005263687 /// XM_005263688 /// XM_005263689 /// XM_005275931 /// XM_005275932 /// XM_005275933 /// XR_244821 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype 211892_s_at AF297052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF297052.1 /DEF=Homo sapiens prostacyclin synthase (CYP8A1) mRNA, CYP8A1*4 allele, complete cds. /FEA=CDS /GEN=CYP8A1 /PROD=prostacyclin synthase /DB_XREF=gi:11139662 /FL=gb:AF297052.1 AF297052 prostaglandin I2 (prostacyclin) synthase PTGIS 5740 NM_000961 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006690 // icosanoid metabolic process // traceable author statement /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008116 // prostaglandin-I synthase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211893_x_at U66145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66145.1 /DEF=Human CD6d mRNA, complete cds. /FEA=CDS /PROD=CD6d /DB_XREF=gi:1903391 /UG=Hs.81226 CD6 antigen /FL=gb:U66145.1 U66145 CD6 molecule CD6 923 NM_001254750 /// NM_001254751 /// NM_006725 /// NR_045638 /// XM_006718738 /// XM_006718739 /// XM_006718740 /// XM_006718741 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211894_x_at AB041736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB041736.1 /DEF=Homo sapiens mRNA for SEZ6L, complete cds. /FEA=CDS /GEN=SEZ6L /PROD=SEZ6L /DB_XREF=gi:13603397 /FL=gb:AB041736.1 AB041736 seizure related 6 homolog (mouse)-like SEZ6L 23544 NM_001184773 /// NM_001184774 /// NM_001184775 /// NM_001184776 /// NM_001184777 /// NM_021115 /// XM_005261439 /// XM_005261440 /// XM_006724195 /// XM_006724196 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 211896_s_at AF138302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF138302.1 /DEF=Homo sapiens decorin variant C mRNA, complete cds. /FEA=CDS /PROD=decorin variant C /DB_XREF=gi:5532412 /UG=Hs.76152 decorin /FL=gb:AF138302.1 AF138302 decorin DCN 1634 NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 211897_s_at AF180301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF180301.1 /DEF=Homo sapiens corticotropin-releasing factor receptor variant 1d (CRHR1) mRNA, alternative splice product, complete cds. /FEA=CDS /GEN=CRHR1 /PROD=corticotropin-releasing factor receptor variant1d /DB_XREF=gi:5815472 /UG=Hs.79117 corticotropin releasing hormone receptor 1 /FL=gb:AF180301.1 AF180301 corticotropin releasing hormone receptor 1 CRHR1 1394 NM_001145146 /// NM_001145147 /// NM_001145148 /// NM_001256299 /// NM_004382 0001666 // response to hypoxia // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007567 // parturition // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010578 // regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0051458 // corticotropin secretion // inferred from sequence or structural similarity /// 0051867 // general adaptation syndrome, behavioral process // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0071376 // cellular response to corticotropin-releasing hormone stimulus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000852 // regulation of corticosterone secretion // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015056 // corticotrophin-releasing factor receptor activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043404 // corticotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0051424 // corticotropin-releasing hormone binding // inferred from electronic annotation 211898_s_at AF037333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF037333.1 /DEF=Homo sapiens Eph-like receptor tyrosine kinase hEphB1c (EphB1) mRNA, complete cds. /FEA=CDS /GEN=EphB1 /PROD=Eph-like receptor tyrosine kinase hEphB1c /DB_XREF=gi:2739207 /UG=Hs.78436 EphB1 /FL=gb:AF037333.1 AF037333 EPH receptor B1 EPHB1 2047 NM_004441 0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211899_s_at AF082185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF082185.1 /DEF=Homo sapiens tumor necrosis factor receptor-associated factor 4A (TRAF4) mRNA, complete cds. /FEA=CDS /GEN=TRAF4 /PROD=tumor necrosis factor receptor-associated factor4A /DB_XREF=gi:3435255 /UG=Hs.8375 TNF receptor-associated factor 4 /FL=gb:AF082185.1 AF082185 TNF receptor-associated factor 4 TRAF4 9618 NM_004295 /// NM_145751 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 211900_x_at U66146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U66146.1 /DEF=Human CD6e mRNA, complete cds. /FEA=CDS /PROD=CD6e /DB_XREF=gi:1903393 /UG=Hs.81226 CD6 antigen /FL=gb:U66146.1 U66146 CD6 molecule CD6 923 NM_001254750 /// NM_001254751 /// NM_006725 /// NR_045638 /// XM_006718738 /// XM_006718739 /// XM_006718740 /// XM_006718741 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211901_s_at AF073745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF073745.2 /DEF=Homo sapiens cyclic AMP-specific phosphodiesterase HSPDE4A10 (PDE4A) mRNA, complete cds. /FEA=CDS /GEN=PDE4A /PROD=cyclic AMP-specific phosphodiesterase HSPDE4A10 /DB_XREF=gi:12057220 /UG=Hs.89901 phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2) /FL=gb:AF073745.2 AF073745 phosphodiesterase 4A, cAMP-specific PDE4A 5141 NM_001111307 /// NM_001111308 /// NM_001111309 /// NM_001243121 /// NM_006202 /// XM_005259933 /// XM_006722765 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0046872 // metal ion binding // inferred from electronic annotation 211902_x_at L34703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L34703.1 /DEF=Homo sapiens T-cell receptor alpha chain (TCRA) mRNA (HLA-A1, 24; B7, 8; DR 1, 3), complete cds. /FEA=CDS /GEN=TCRA /PROD=T-cell receptor alpha /DB_XREF=gi:1100165 /UG=Hs.74647 Human T-cell receptor active alpha-chain mRNA from JM cell line, complete cds /FL=gb:L34703.1 L34703 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 211903_s_at M90103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90103.1 /DEF=Human (clones 18, 23, 27, 24) c-myeloproliferative leukemia virus type K (c-mpl-K) mRNA, complete cds. /FEA=CDS /GEN=c-mpl-K /PROD=c-myeloproliferative leukemia virus type K /DB_XREF=gi:184262 /UG=Hs.84171 myeloproliferative leukemia virus oncogene /FL=gb:M90103.1 M90103 MPL proto-oncogene, thrombopoietin receptor MPL 4352 NM_005373 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032642 // regulation of chemokine production // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 211904_x_at AF125950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF125950.1 /DEF=Homo sapiens DNA repair protein RAD52 beta isoform (RAD52) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=RAD52 /PROD=DNA repair protein RAD52 beta isoform /DB_XREF=gi:4581009 /UG=Hs.89571 RAD52 (S. cerevisiae) homolog /FL=gb:AF125950.1 AF125950 RAD52 homolog (S. cerevisiae) RAD52 5893 NM_001297419 /// NM_001297420 /// NM_001297421 /// NM_001297422 /// NM_134422 /// NM_134423 /// NM_134424 /// NR_123713 /// XM_005253720 /// XM_005253721 /// XM_005253725 /// XM_005253727 /// XM_006718995 /// XM_006718996 /// XM_006718997 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from mutant phenotype /// 0006312 // mitotic recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 211905_s_at AF011375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF011375.1 /DEF=Homo sapiens integrin variant beta4E (ITGB4) mRNA, complete cds. /FEA=CDS /GEN=ITGB4 /PROD=integrin variant beta4E /DB_XREF=gi:2293520 /UG=Hs.85266 integrin, beta 4 /FL=gb:AF011375.1 AF011375 integrin, beta 4 ITGB4 3691 NM_000213 /// NM_001005619 /// NM_001005731 /// XM_005257309 /// XM_005257311 /// XM_005257312 /// XM_006721866 /// XM_006721867 /// XM_006721868 /// XM_006721869 /// XM_006721870 0006914 // autophagy // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211906_s_at AB046400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB046400.1 /DEF=Homo sapiens mRNA for SCCA2b, complete cds. /FEA=CDS /GEN=SCCA2 /PROD=SCCA2b /DB_XREF=gi:13537193 /FL=gb:AB046400.1 AB046400 serpin peptidase inhibitor, clade B (ovalbumin), member 4 SERPINB4 6318 NM_002974 0006955 // immune response // non-traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 211907_s_at AB044555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044555.1 /DEF=Homo sapiens mRNA for PAR-6 beta, complete cds. /FEA=CDS /GEN=Par-6 beta /PROD=PAR-6 beta /DB_XREF=gi:13537116 /FL=gb:AB044555.1 AB044555 par-6 family cell polarity regulator beta PARD6B 84612 NM_032521 0006461 // protein complex assembly // inferred from direct assay /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0030334 // regulation of cell migration // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 211908_x_at M87268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M87268.1 /DEF=Human IgM VDJ-region mRNA, complete cds. /FEA=CDS /GEN=IGHM /PROD=IgM /DB_XREF=gi:186197 /FL=gb:M87268.1 M87268 immunoglobulin kappa locus IGK 50802 211909_x_at L32662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L32662.1 /DEF=Human prostaglandin E2 receptor EP3 subtype isoform IV mRNA, complete cds. /FEA=CDS /PROD=prostaglandin E2 receptor /DB_XREF=gi:484163 /FL=gb:L32662.1 L32662 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 211910_at U87229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U87229.1 /DEF=Homo sapiens death adaptor molecule RAIDD-2 mRNA, complete cds. /FEA=CDS /PROD=death adaptor molecule RAIDD-2 /DB_XREF=gi:5051867 /FL=gb:U87229.1 U87229 0007165 // signal transduction // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 211911_x_at L07950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L07950.1 /DEF=Homo sapiens MHC class I HLA B71 mRNA, complete cds. /FEA=CDS /GEN=HLA-B /PROD=MHC HLA B71 /DB_XREF=gi:307236 /FL=gb:L07950.1 L07950 major histocompatibility complex, class I, B HLA-B 3106 NM_005514 /// XM_005249043 /// XM_005275100 /// XM_005275238 /// XM_005275376 /// XM_005275377 /// XM_005275535 /// XM_006725904 /// XM_006725905 /// XR_246962 /// XR_427830 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0002667 // regulation of T cell anergy // inferred from mutant phenotype /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032655 // regulation of interleukin-12 production // inferred from mutant phenotype /// 0032675 // regulation of interleukin-6 production // inferred from mutant phenotype /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2001198 // regulation of dendritic cell differentiation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005102 // receptor binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 211912_at L08961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L08961.1 /DEF=Homo sapiens transmembrane tyrosine kinase mRNA, complete cds. /FEA=CDS /PROD=tyrosine kinase /DB_XREF=gi:897614 /FL=gb:L08961.1 L08961 MER proto-oncogene, tyrosine kinase MERTK 10461 NM_006343 /// XM_005263565 /// XM_005263568 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006909 // phagocytosis // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016028 // rhabdomere // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211913_s_at L08961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L08961.1 /DEF=Homo sapiens transmembrane tyrosine kinase mRNA, complete cds. /FEA=CDS /PROD=tyrosine kinase /DB_XREF=gi:897614 /FL=gb:L08961.1 L08961 MER proto-oncogene, tyrosine kinase MERTK 10461 NM_006343 /// XM_005263565 /// XM_005263568 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006909 // phagocytosis // inferred from mutant phenotype /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016028 // rhabdomere // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 211914_x_at M60915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M60915.1 /DEF=Human neurofibromatosis protein type I (NF1) mRNA, complete cds. /FEA=CDS /GEN=NF1; NF1 /PROD=neurofibromatosis protein type 1; neurofibromatosis protein type 1 /DB_XREF=gi:189159 /FL=gb:M60915.1 M60915 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 211915_s_at U83110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U83110.1 /DEF=Human beta-tubulin (TUB4q) mRNA, complete cds. /FEA=CDS /GEN=TUB4q /PROD=beta-tubulin /DB_XREF=gi:1805272 /FL=gb:U83110.1 U83110 tubulin, beta 7, pseudogene TUBB7P 56604 NM_020040 211916_s_at AF009961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF009961.1 /DEF=Homo sapiens brush border myosin-I mRNA, complete cds. /FEA=CDS /PROD=brush border myosin-I /DB_XREF=gi:3337397 /FL=gb:AF009961.1 AF009961 myosin IA MYO1A 4640 NM_001256041 /// NM_005379 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0051648 // vesicle localization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005903 // brush border // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 211917_s_at AF349939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349939.1 /DEF=Homo sapiens prolactin receptor isoform delta S1 precursor, mRNA, complete cds. /FEA=CDS /PROD=prolactin receptor isoform delta S1 precursor /DB_XREF=gi:13605397 /FL=gb:AF349939.1 AF349939 prolactin receptor PRLR 5618 NM_000949 /// NM_001204314 /// NM_001204315 /// NM_001204316 /// NM_001204317 /// NM_001204318 /// NR_037910 /// XM_006714484 0006694 // steroid biosynthetic process // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007566 // embryo implantation // traceable author statement /// 0007595 // lactation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // non-traceable author statement /// 0038161 // prolactin signaling pathway // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042977 // activation of JAK2 kinase activity // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004925 // prolactin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042978 // ornithine decarboxylase activator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 211918_x_at AF311940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF311940.1 /DEF=Homo sapiens pregnancy-associated plasma preproprotein-A2 mRNA, complete cds. /FEA=CDS /PROD=pregnancy-associated plasma preproprotein-A2 /DB_XREF=gi:13569344 /FL=gb:AF311940.1 AF311940 pappalysin 2 PAPPA2 60676 NM_020318 /// NM_021936 /// XM_005245422 0001558 // regulation of cell growth // non-traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211919_s_at AF348491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348491.1 /DEF=Homo sapiens chemokine receptor CXCR4 mRNA, complete cds. /FEA=CDS /PROD=chemokine receptor CXCR4 /DB_XREF=gi:13549089 /FL=gb:AF348491.1 AF348491 chemokine (C-X-C motif) receptor 4 CXCR4 7852 NM_001008540 /// NM_003467 0000187 // activation of MAPK activity // traceable author statement /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030260 // entry into host cell // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042119 // neutrophil activation // inferred from electronic annotation /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // non-traceable author statement /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // non-traceable author statement /// 0019955 // cytokine binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032027 // myosin light chain binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 211920_at AF349679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF349679.1 /DEF=Homo sapiens factor B (FBI12) mRNA, complete cds, alternatively spliced. /FEA=CDS /GEN=FBI12 /PROD=factor B /DB_XREF=gi:13560704 /FL=gb:AF349679.1 AF349679 complement factor B CFB 629 NM_001710 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // non-traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 211921_x_at AF348514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348514.1 /DEF=Homo sapiens fetal thymus prothymosin alpha mRNA, complete cds. /FEA=CDS /PROD=prothymosin alpha /DB_XREF=gi:13560658 /FL=gb:AF348514.1 AF348514 prothymosin alpha-like /// prothymosin alpha-like /// microRNA 1244-1 /// microRNA 1244-2 /// microRNA 1244-3 /// prothymosin, alpha LOC100506248 /// LOC728026 /// MIR1244-1 /// MIR1244-2 /// MIR1244-3 /// PTMA 5757 /// 728026 /// 100302285 /// 100422872 /// 100422885 /// 100506248 NM_001099285 /// NM_002823 /// NR_036052 /// NR_036262 /// NR_036263 /// XM_001126659 /// XM_003960458 /// XM_005275719 /// XM_005276418 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 211922_s_at AY028632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY028632.1 /DEF=Homo sapiens catalase (CAT) mRNA, complete cds. /FEA=CDS /GEN=CAT /PROD=catalase /DB_XREF=gi:13562131 /FL=gb:AY028632.1 AY028632 catalase CAT 847 NM_001752 0000302 // response to reactive oxygen species // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042697 // menopause // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0004096 // catalase activity // inferred from direct assay /// 0004096 // catalase activity // traceable author statement /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay 211923_s_at AF352026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF352026.1 /DEF=Homo sapiens EZFIT-related protein 1 mRNA, complete cds. /FEA=CDS /PROD=EZFIT-related protein 1 /DB_XREF=gi:13560887 /FL=gb:AF352026.1 AF352026 zinc finger protein 471 ZNF471 57573 NM_020813 /// XM_005259096 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 211924_s_at AY029180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY029180.1 /DEF=Homo sapiens soluble urokinase plasminogen activator receptor precursor (SUPAR) mRNA, complete cds. /FEA=CDS /GEN=SUPAR /PROD=soluble urokinase plasminogen activator receptorprecursor /DB_XREF=gi:13641308 /FL=gb:AY029180.1 AY029180 plasminogen activator, urokinase receptor PLAUR 5329 NM_001005376 /// NM_001005377 /// NM_002659 /// XM_005258988 /// XM_005258989 /// XM_005258990 /// XM_006723241 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030162 // regulation of proteolysis // non-traceable author statement /// 0038195 // urokinase plasminogen activator signaling pathway // non-traceable author statement /// 0042730 // fibrinolysis // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030377 // urokinase plasminogen activator receptor activity // non-traceable author statement 211925_s_at AY004175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY004175.1 /DEF=Homo sapiens phospholipase C beta 1 mRNA, complete cds. /FEA=CDS /PROD=phospholipase C beta 1 /DB_XREF=gi:9438228 /UG=Hs.41143 phosphoinositide-specific phospholipase C-beta 1 /FL=gb:AY004175.1 AY004175 phospholipase C, beta 1 (phosphoinositide-specific) PLCB1 23236 NM_015192 /// NM_182734 /// XM_005260681 /// XM_006723555 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007215 // glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007613 // memory // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0035723 // interleukin-15-mediated signaling pathway // inferred from direct assay /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048639 // positive regulation of developmental growth // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060466 // activation of meiosis involved in egg activation // inferred from sequence or structural similarity /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0080154 // regulation of fertilization // inferred from sequence or structural similarity /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity /// 2000344 // positive regulation of acrosome reaction // inferred from sequence or structural similarity /// 2000438 // negative regulation of monocyte extravasation // inferred from sequence or structural similarity /// 2000560 // positive regulation of CD24 biosynthetic process // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from sequence or structural similarity /// 0004435 // phosphatidylinositol phospholipase C activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 211926_s_at AI827941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI827941 /FEA=EST /DB_XREF=gi:5448699 /DB_XREF=est:wk31a02.x1 /CLONE=IMAGE:2413898 /UG=Hs.146550 myosin, heavy polypeptide 9, non-muscle /FL=gb:NM_002473.1 AI827941 myosin, heavy chain 9, non-muscle MYH9 4627 NM_002473 0000212 // meiotic spindle organization // inferred from electronic annotation /// 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001768 // establishment of T cell polarity // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0015031 // protein transport // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0030220 // platelet formation // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from expression pattern /// 0031032 // actomyosin structure organization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032796 // uropod organization // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043534 // blood vessel endothelial cell migration // inferred from mutant phenotype /// 0050900 // leukocyte migration // non-traceable author statement /// 0051295 // establishment of meiotic spindle localization // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0001726 // ruffle // inferred from direct assay /// 0001772 // immunological synapse // inferred from direct assay /// 0001931 // uropod // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005826 // actomyosin contractile ring // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0008305 // integrin complex // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0042641 // actomyosin // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003774 // motor activity // non-traceable author statement /// 0003779 // actin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0043531 // ADP binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // non-traceable author statement 211927_x_at BE963164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963164 /FEA=EST /DB_XREF=gi:11766582 /DB_XREF=est:601656973R1 /CLONE=IMAGE:3865650 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma BE963164 eukaryotic translation elongation factor 1 gamma /// microRNA 3654 EEF1G /// MIR3654 1937 /// 100500804 NM_001404 /// NR_037427 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 211928_at AB002323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002323.1 /DEF=Human mRNA for KIAA0325 gene, partial cds. /FEA=mRNA /GEN=KIAA0325 /DB_XREF=gi:2224590 /UG=Hs.7720 dynein, cytoplasmic, heavy polypeptide 1 AB002323 dynein, cytoplasmic 1, heavy chain 1 DYNC1H1 1778 NM_001376 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007052 // mitotic spindle organization // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from sequence or structural similarity /// 0034063 // stress granule assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211929_at AA527502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527502 /FEA=EST /DB_XREF=gi:2269571 /DB_XREF=est:ng41f10.s1 /CLONE=IMAGE:937387 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein AA527502 heterogeneous nuclear ribonucleoprotein A3 HNRNPA3 220988 NM_194247 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211930_at AW080932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW080932 /FEA=EST /DB_XREF=gi:6036084 /DB_XREF=est:xc28a11.x1 /CLONE=IMAGE:2585564 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein AW080932 heterogeneous nuclear ribonucleoprotein A3 HNRNPA3 220988 NM_194247 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211931_s_at BG505670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG505670 /FEA=EST /DB_XREF=gi:13467187 /DB_XREF=est:602549833F1 /CLONE=IMAGE:4657424 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein BG505670 heterogeneous nuclear ribonucleoprotein A3 /// heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 HNRNPA3 /// HNRNPA3P1 10151 /// 220988 NM_194247 /// NR_002726 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211932_at BF195526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195526 /FEA=EST /DB_XREF=gi:11082509 /DB_XREF=est:7n89c08.x1 /CLONE=IMAGE:3571599 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein BF195526 heterogeneous nuclear ribonucleoprotein A3 HNRNPA3 220988 NM_194247 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211933_s_at AA528233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA528233 /FEA=EST /DB_XREF=gi:2270302 /DB_XREF=est:nh92b01.s1 /CLONE=IMAGE:965929 /UG=Hs.249247 heterogeneous nuclear protein similar to rat helix destabilizing protein AA528233 heterogeneous nuclear ribonucleoprotein A3 /// heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 HNRNPA3 /// HNRNPA3P1 10151 /// 220988 NM_194247 /// NR_002726 /// XM_005246380 /// XM_005246381 /// XM_005246382 /// XM_006712365 /// XR_427076 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211934_x_at W87689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87689 /FEA=EST /DB_XREF=gi:1401814 /DB_XREF=est:zh68c04.s1 /CLONE=IMAGE:417222 /UG=Hs.76847 KIAA0088 protein /FL=gb:NM_014610.1 W87689 glucosidase, alpha; neutral AB GANAB 23193 NM_001278192 /// NM_001278193 /// NM_001278194 /// NM_014610 /// NM_198334 /// NM_198335 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0017177 // glucosidase II complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0033919 // glucan 1,3-alpha-glucosidase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211935_at D31885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D31885.1 /DEF=Human mRNA for KIAA0069 gene, partial cds. /FEA=mRNA /GEN=KIAA0069 /DB_XREF=gi:505097 /UG=Hs.75249 ADP-ribosylation factor-like 6 interacting protein D31885 ADP-ribosylation factor-like 6 interacting protein 1 ARL6IP1 23204 NM_015161 0006613 // cotranslational protein targeting to membrane // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005784 // Sec61 translocon complex // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 211936_at AF216292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF216292.1 /DEF=Homo sapiens endoplasmic reticulum lumenal Ca2+ binding protein grp78 mRNA, complete cds. /FEA=CDS /PROD=endoplasmic reticulum lumenal Ca2+ bindingprotein grp78 /DB_XREF=gi:7229461 /UG=Hs.75410 heat shock 70kD protein 5 (glucose-regulated protein, 78kD) /FL=gb:AF216292.1 AF216292 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) HSPA5 3309 NM_005347 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006983 // ER overload response // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021589 // cerebellum structural organization // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030168 // platelet activation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035437 // maintenance of protein localization in endoplasmic reticulum // inferred from mutant phenotype /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0060904 // regulation of protein folding in endoplasmic reticulum // traceable author statement /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0034663 // endoplasmic reticulum chaperone complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement /// 0051787 // misfolded protein binding // inferred from direct assay 211937_at NM_001417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001417.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4B (EIF4B), mRNA. /FEA=CDS /GEN=EIF4B /PROD=eukaryotic translation initiation factor 4B /DB_XREF=gi:4503532 /UG=Hs.93379 eukaryotic translation initiation factor 4B /FL=gb:NM_001417.1 NM_001417 eukaryotic translation initiation factor 4B EIF4B 1975 NM_001417 /// NM_018507 /// XM_005268709 /// XM_006719274 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211938_at BF247371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF247371 /FEA=EST /DB_XREF=gi:11162727 /DB_XREF=est:601858130F1 /CLONE=IMAGE:4068630 /UG=Hs.283330 hypothetical protein PRO1843 BF247371 eukaryotic translation initiation factor 4B EIF4B 1975 NM_001417 /// NM_018507 /// XM_005268709 /// XM_006719274 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211939_x_at X74070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X74070.1 /DEF=H.sapiens mRNA for transcription factor BTF 3. /FEA=mRNA /PROD=transcription factor BTF3 /DB_XREF=gi:395086 /UG=Hs.101025 basic transcription factor 3 X74070 basic transcription factor 3 BTF3 689 NM_001037637 /// NM_001207 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211940_x_at BE869922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE869922 /FEA=EST /DB_XREF=gi:10318698 /DB_XREF=est:601446568F1 /CLONE=IMAGE:3850432 /UG=Hs.181307 H3 histone, family 3A BE869922 H3 histone, family 3A /// H3 histone, family 3A, pseudogene 4 /// H3 histone, family 3B (H3.3B) H3F3A /// H3F3AP4 /// H3F3B 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211941_s_at BE969671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE969671 /FEA=EST /DB_XREF=gi:10582604 /DB_XREF=est:601679610F1 /CLONE=IMAGE:3949779 /UG=Hs.80423 prostatic binding protein BE969671 phosphatidylethanolamine binding protein 1 PEBP1 5037 NM_002567 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211942_x_at BF979419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF979419 /FEA=EST /DB_XREF=gi:12346634 /DB_XREF=est:602288246F1 /CLONE=IMAGE:4373914 /UG=Hs.119122 ribosomal protein L13a BF979419 ribosomal protein L13a /// ribosomal protein L13a pseudogene 5 /// ribosomal protein L13a pseudogene 6 /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A RPL13A /// RPL13AP5 /// RPL13AP6 /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 /// 644511 /// 728658 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_026712 /// NR_026715 /// NR_073024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211943_x_at AL565449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565449 /FEA=EST /DB_XREF=gi:12916836 /DB_XREF=est:AL565449 /CLONE=CS0DF005YE20 (3 prime) /UG=Hs.279860 tumor protein, translationally-controlled 1 AL565449 uncharacterized LOC101928826 /// tumor protein, translationally-controlled 1 LOC101928826 /// TPT1 7178 /// 101928826 NM_001286272 /// NM_001286273 /// NM_003295 /// XR_242670 /// XR_250536 /// XR_252641 0006816 // calcium ion transport // inferred by curator /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0009615 // response to virus // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000384 // negative regulation of ectoderm development // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005771 // multivesicular body // inferred from direct assay /// 0045298 // tubulin complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211944_at BE729523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE729523 /FEA=EST /DB_XREF=gi:10143515 /DB_XREF=est:601564896F1 /CLONE=IMAGE:3926279 /UG=Hs.69559 KIAA1096 protein BE729523 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0016020 // membrane // inferred from direct assay 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211945_s_at BG500301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG500301 /FEA=EST /DB_XREF=gi:13461818 /DB_XREF=est:602546969F1 /CLONE=IMAGE:4669168 /UG=Hs.287797 Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), mRNA BG500301 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ITGB1 3688 NM_002211 /// NM_033666 /// NM_033667 /// NM_033668 /// NM_033669 /// NM_133376 /// XM_005252448 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007161 // calcium-independent cell-matrix adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032594 // protein transport within lipid bilayer // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001726 // ruffle // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0001968 // fibronectin binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation 211946_s_at AL096857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096857.1 /DEF=Novel human mRNA from chromosome 1, which has similarities to BAT2 genes. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:5541862 /UG=Hs.69559 KIAA1096 protein AL096857 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0016020 // membrane // inferred from direct assay 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211947_s_at AI359472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI359472 /FEA=EST /DB_XREF=gi:4111093 /DB_XREF=est:qx94a03.x1 /CLONE=IMAGE:2010124 /UG=Hs.69559 KIAA1096 protein AI359472 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0016020 // membrane // inferred from direct assay 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211948_x_at BG261071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG261071 /FEA=EST /DB_XREF=gi:12770887 /DB_XREF=est:602372693F1 /CLONE=IMAGE:4480631 /UG=Hs.69559 KIAA1096 protein BG261071 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0016020 // membrane // inferred from direct assay 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211949_s_at AI355279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI355279 /FEA=EST /DB_XREF=gi:4095432 /DB_XREF=est:qt79f12.x1 /CLONE=IMAGE:1961519 /UG=Hs.75337 nucleolar phosphoprotein p130 AI355279 nucleolar and coiled-body phosphoprotein 1 NOLC1 9221 NM_001284388 /// NM_001284389 /// NM_004741 /// XM_005270273 0006364 // rRNA processing // traceable author statement /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211950_at AB007931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007931.1 /DEF=Homo sapiens mRNA for KIAA0462 protein, partial cds. /FEA=mRNA /GEN=KIAA0462 /PROD=KIAA0462 protein /DB_XREF=gi:3413885 /UG=Hs.297641 KIAA0462 protein AB007931 ubiquitin protein ligase E3 component n-recognin 4 UBR4 23352 NM_020765 /// XM_005245802 /// XM_006710503 /// XM_006710504 /// XM_006710505 /// XM_006710506 /// XM_006710507 /// XM_006710508 /// XM_006710509 /// XM_006710510 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211951_at D21262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D21262.1 /DEF=Human mRNA for KIAA0035 gene, partial cds. /FEA=mRNA /GEN=KIAA0035 /PROD=ORF /DB_XREF=gi:434764 /UG=Hs.75337 nucleolar phosphoprotein p130 D21262 nucleolar and coiled-body phosphoprotein 1 NOLC1 9221 NM_001284388 /// NM_001284389 /// NM_004741 /// XM_005270273 0006364 // rRNA processing // traceable author statement /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 211952_at AF339834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339834.1 /DEF=Homo sapiens clone IMAGE:898206, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507372 /UG=Hs.113503 karyopherin (importin) beta 3 /FL=gb:U72761.1 gb:NM_002271.1 AF339834 importin 5 IPO5 3843 NM_002271 /// XM_005254049 /// XM_005254052 /// XM_005254053 0006607 // NLS-bearing protein import into nucleus // inferred from sequence or structural similarity /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 211953_s_at AU148466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148466 /FEA=EST /DB_XREF=gi:11009987 /DB_XREF=est:AU148466 /CLONE=NT2RM4000332 /UG=Hs.113503 karyopherin (importin) beta 3 /FL=gb:U72761.1 gb:NM_002271.1 AU148466 importin 5 IPO5 3843 NM_002271 /// XM_005254049 /// XM_005254052 /// XM_005254053 0006607 // NLS-bearing protein import into nucleus // inferred from sequence or structural similarity /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 211954_s_at BC000947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000947.2 /DEF=Homo sapiens, clone IMAGE:3450586, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3450586) /DB_XREF=gi:13111828 /UG=Hs.113503 karyopherin (importin) beta 3 /FL=gb:U72761.1 gb:NM_002271.1 BC000947 importin 5 IPO5 3843 NM_002271 /// XM_005254049 /// XM_005254052 /// XM_005254053 0006607 // NLS-bearing protein import into nucleus // inferred from sequence or structural similarity /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 211955_at NM_002271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002271.1 /DEF=Homo sapiens karyopherin (importin) beta 3 (KPNB3), mRNA. /FEA=CDS /GEN=KPNB3 /PROD=karyopherin (importin) beta 3 /DB_XREF=gi:4504908 /UG=Hs.113503 karyopherin (importin) beta 3 /FL=gb:U72761.1 gb:NM_002271.1 NM_002271 importin 5 IPO5 3843 NM_002271 /// XM_005254049 /// XM_005254052 /// XM_005254053 0006607 // NLS-bearing protein import into nucleus // inferred from sequence or structural similarity /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 211956_s_at BF246436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF246436 /FEA=EST /DB_XREF=gi:11160799 /DB_XREF=est:601854870F1 /CLONE=IMAGE:4074785 /UG=Hs.150580 putative translation initiation factor BF246436 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 211958_at R73554 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R73554 /FEA=EST /DB_XREF=gi:847586 /DB_XREF=est:yj94e05.s1 /CLONE=IMAGE:156416 /UG=Hs.103391 Human insulin-like growth factor binding protein 5 (IGFBP5) mRNA R73554 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 211959_at AW007532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007532 /FEA=EST /DB_XREF=gi:5856310 /DB_XREF=est:ws52h07.x1 /CLONE=IMAGE:2500861 /UG=Hs.103391 Human insulin-like growth factor binding protein 5 (IGFBP5) mRNA AW007532 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 211960_s_at BG261416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG261416 /FEA=EST /DB_XREF=gi:12771232 /DB_XREF=est:602373192F1 /CLONE=IMAGE:4484422 /UG=Hs.237955 hypothetical protein PRO2706 BG261416 RAB7A, member RAS oncogene family RAB7A 7879 NM_004637 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007174 // epidermal growth factor catabolic process // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 0090383 // phagosome acidification // inferred from mutant phenotype /// 0090385 // phagosome-lysosome fusion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 211961_s_at AK000826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000826.1 /DEF=Homo sapiens cDNA FLJ20819 fis, clone ADSE00511. /FEA=mRNA /DB_XREF=gi:7021139 /UG=Hs.237955 hypothetical protein PRO2706 AK000826 RAB7A, member RAS oncogene family RAB7A 7879 NM_004637 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007174 // epidermal growth factor catabolic process // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 0090383 // phagosome acidification // inferred from mutant phenotype /// 0090385 // phagosome-lysosome fusion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 211962_s_at BG250310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG250310 /FEA=EST /DB_XREF=gi:12760126 /DB_XREF=est:602362443F1 /CLONE=IMAGE:4470898 /UG=Hs.85155 butyrate response factor 1 (EGF-response factor 1) BG250310 ZFP36 ring finger protein-like 1 ZFP36L1 677 NM_001244698 /// NM_001244701 /// NM_004926 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211963_s_at AL516350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL516350 /FEA=EST /DB_XREF=gi:12779843 /DB_XREF=est:AL516350 /CLONE=CS0DA005YD24 (3 prime) /UG=Hs.82425 actin related protein 23 complex, subunit 5 (16 kD) /FL=gb:AF017807.1 AL516350 actin related protein 2/3 complex, subunit 5, 16kDa ARPC5 10092 NM_001270439 /// NM_005717 0006928 // cellular component movement // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211964_at X05610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X05610.1 /DEF=Human mRNA for type IV collagen alpha (2) chain. /FEA=mRNA /PROD=alpha (2) chain /DB_XREF=gi:29550 /UG=Hs.75617 collagen, type IV, alpha 2 X05610 collagen, type IV, alpha 2 COL4A2 1284 NM_001846 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211965_at BE620915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE620915 /FEA=EST /DB_XREF=gi:9891853 /DB_XREF=est:601483777T1 /CLONE=IMAGE:3886194 /UG=Hs.85155 butyrate response factor 1 (EGF-response factor 1) BE620915 ZFP36 ring finger protein-like 1 ZFP36L1 677 NM_001244698 /// NM_001244701 /// NM_004926 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 211966_at AA909035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA909035 /FEA=EST /DB_XREF=gi:3048440 /DB_XREF=est:ol11h01.s1 /CLONE=IMAGE:1523185 /UG=Hs.75617 collagen, type IV, alpha 2 AA909035 collagen, type IV, alpha 2 COL4A2 1284 NM_001846 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 211967_at BG538627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG538627 /FEA=EST /DB_XREF=gi:13530860 /DB_XREF=est:602567359F1 /CLONE=IMAGE:4691726 /UG=Hs.172089 Homo sapiens mRNA; cDNA DKFZp586I2022 (from clone DKFZp586I2022) BG538627 transmembrane protein 123 TMEM123 114908 NM_052932 0070267 // oncosis // inferred from direct assay 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004872 // receptor activity // non-traceable author statement 211968_s_at AI962933 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962933 /FEA=EST /DB_XREF=gi:5755646 /DB_XREF=est:wt25a07.x1 /CLONE=IMAGE:2508468 /UG=Hs.289088 heat shock 90kD protein 1, alpha /FL=gb:NM_005348.1 AI962933 heat shock protein 90kDa alpha (cytosolic), class A member 1 HSP90AA1 3320 NM_001017963 /// NM_005348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0030911 // TPR domain binding // inferred from direct assay /// 0030911 // TPR domain binding // traceable author statement /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 211969_at BG420237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG420237 /FEA=EST /DB_XREF=gi:13326743 /DB_XREF=est:602448244F1 /CLONE=IMAGE:4586914 /UG=Hs.289088 heat shock 90kD protein 1, alpha /FL=gb:NM_005348.1 BG420237 heat shock protein 90kDa alpha (cytosolic), class A member 1 HSP90AA1 3320 NM_001017963 /// NM_005348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0030911 // TPR domain binding // inferred from direct assay /// 0030911 // TPR domain binding // traceable author statement /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 211970_x_at BG026805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG026805 /FEA=EST /DB_XREF=gi:12414790 /DB_XREF=est:602294278F1 /CLONE=IMAGE:4388898 /UG=Hs.14376 actin, gamma 1 BG026805 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 211971_s_at AI653608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653608 /FEA=EST /DB_XREF=gi:4737587 /DB_XREF=est:tz21a06.x1 /CLONE=IMAGE:2289202 /UG=Hs.182490 leucine-rich protein mRNA AI653608 leucine-rich pentatricopeptide repeat containing LRPPRC 10128 NM_133259 /// XM_006711915 /// XM_006711916 0000961 // negative regulation of mitochondrial RNA catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0070129 // regulation of mitochondrial translation // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 211972_x_at AI953822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI953822 /FEA=EST /DB_XREF=gi:5746132 /DB_XREF=est:wx69h05.x1 /CLONE=IMAGE:2548953 /UG=Hs.73742 ribosomal protein, large, P0 AI953822 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 211973_at AW341200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW341200 /FEA=EST /DB_XREF=gi:6837826 /DB_XREF=est:xz95g12.x1 /CLONE=IMAGE:2872006 /UG=Hs.188882 Homo sapiens cDNA: FLJ21862 fis, clone HEP02321, highly similar to AF052101 Homo sapiens clone 23872 mRNA sequence AW341200 nudix (nucleoside diphosphate linked moiety X)-type motif 3 NUDT3 11165 NM_006703 0007267 // cell-cell signaling // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 211974_x_at AL513759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL513759 /FEA=EST /DB_XREF=gi:12777253 /DB_XREF=est:AL513759 /CLONE=CL0BA008ZD02 (3 prime) /UG=Hs.278573 Homo sapiens similar to J KAPPA-RECOMBINATION SIGNAL BINDING PROTEIN (M. musculus) (LOC65437), mRNA AL513759 recombination signal binding protein for immunoglobulin kappa J region RBPJ 3516 NM_005349 /// NM_015874 /// NM_203283 /// NM_203284 /// XM_005248161 /// XM_006713962 /// XM_006713963 /// XM_006713964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003157 // endocardium development // inferred from electronic annotation /// 0003160 // endocardium morphogenesis // inferred from sequence or structural similarity /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009912 // auditory receptor cell fate commitment // inferred from electronic annotation /// 0009957 // epidermal cell fate specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048820 // hair follicle maturation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060486 // Clara cell differentiation // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060844 // arterial endothelial cell fate commitment // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072554 // blood vessel lumenization // inferred from sequence or structural similarity /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0097101 // blood vessel endothelial cell fate specification // inferred from sequence or structural similarity /// 1901186 // positive regulation of ERBB signaling pathway // inferred from sequence or structural similarity /// 1901189 // positive regulation of ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000150 // recombinase activity // non-traceable author statement /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 211975_at BE299671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE299671 /FEA=EST /DB_XREF=gi:9183419 /DB_XREF=est:600944342T1 /CLONE=IMAGE:2960218 /UG=Hs.256310 protein kinase C and casein kinase substrate in neurons 3 BE299671 ADP-ribosylation factor GTPase activating protein 2 ARFGAP2 84364 NM_001242832 /// NM_032389 /// XM_005253166 /// XM_005253167 /// XM_005253168 /// XM_006718346 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 211976_at AK026168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026168.1 /DEF=Homo sapiens cDNA: FLJ22515 fis, clone HRC12122, highly similar to AF052101 Homo sapiens clone 23872 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10438931 /UG=Hs.188882 Homo sapiens cDNA: FLJ21862 fis, clone HEP02321, highly similar to AF052101 Homo sapiens clone 23872 mRNA sequence AK026168 nudix (nucleoside diphosphate linked moiety X)-type motif 3 NUDT3 11165 NM_006703 0007267 // cell-cell signaling // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 211977_at AK024651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024651.1 /DEF=Homo sapiens cDNA: FLJ20998 fis, clone CAE03125. /FEA=mRNA /DB_XREF=gi:10436978 /UG=Hs.6639 KIAA1624 protein AK024651 G protein-coupled receptor 107 GPR107 57720 NM_001136557 /// NM_001136558 /// NM_001287346 /// NM_020960 /// XM_006717196 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019236 // response to pheromone // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211978_x_at AI708767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI708767 /FEA=EST /DB_XREF=gi:4998543 /DB_XREF=est:as35e01.x1 /CLONE=IMAGE:2319192 /UG=Hs.267690 KIAA1228 protein AI708767 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 211979_at AB046844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046844.1 /DEF=Homo sapiens mRNA for KIAA1624 protein, partial cds. /FEA=mRNA /GEN=KIAA1624 /PROD=KIAA1624 protein /DB_XREF=gi:10047324 /UG=Hs.6639 KIAA1624 protein AB046844 G protein-coupled receptor 107 GPR107 57720 NM_001136557 /// NM_001136558 /// NM_001287346 /// NM_020960 /// XM_006717196 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019236 // response to pheromone // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211980_at AI922605 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922605 /FEA=EST /DB_XREF=gi:5658569 /DB_XREF=est:wm90c05.x1 /CLONE=IMAGE:2443208 /UG=Hs.119129 collagen, type IV, alpha 1 /FL=gb:NM_001845.1 AI922605 collagen, type IV, alpha 1 COL4A1 1282 NM_001845 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from mutant phenotype /// 0061304 // retinal blood vessel morphogenesis // inferred from mutant phenotype /// 0061333 // renal tubule morphogenesis // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred by curator /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred by curator /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 211981_at NM_001845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001845.1 /DEF=Homo sapiens collagen, type IV, alpha 1 (COL4A1), mRNA. /FEA=CDS /GEN=COL4A1 /PROD=collagen, type IV, alpha 1 /DB_XREF=gi:7656984 /UG=Hs.119129 collagen, type IV, alpha 1 /FL=gb:NM_001845.1 NM_001845 collagen, type IV, alpha 1 COL4A1 1282 NM_001845 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from mutant phenotype /// 0061304 // retinal blood vessel morphogenesis // inferred from mutant phenotype /// 0061333 // renal tubule morphogenesis // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred by curator /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred by curator /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 211982_x_at AL546600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL546600 /FEA=EST /DB_XREF=gi:12879872 /DB_XREF=est:AL546600 /CLONE=CS0DI029YA23 (3 prime) /UG=Hs.70500 KIAA0370 protein AL546600 exportin 6 XPO6 23214 NM_001270940 /// NM_015171 /// XM_005255195 /// XM_005255197 /// XM_005255198 /// XM_005255199 /// XM_005255200 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay 211983_x_at BE741683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE741683 /FEA=EST /DB_XREF=gi:10155675 /DB_XREF=est:601594740F1 /CLONE=IMAGE:3948897 /UG=Hs.14376 actin, gamma 1 BE741683 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 211984_at AI653730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653730 /FEA=EST /DB_XREF=gi:4737709 /DB_XREF=est:wb36f12.x1 /CLONE=IMAGE:2307791 /UG=Hs.279009 matrix Gla protein AI653730 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 211985_s_at AI653730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653730 /FEA=EST /DB_XREF=gi:4737709 /DB_XREF=est:wb36f12.x1 /CLONE=IMAGE:2307791 /UG=Hs.279009 matrix Gla protein AI653730 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 211986_at BG287862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG287862 /FEA=EST /DB_XREF=gi:13042118 /DB_XREF=est:602387619F1 /CLONE=IMAGE:4516588 /UG=Hs.301417 AHNAK nucleoprotein (desmoyokin) BG287862 AHNAK nucleoprotein AHNAK 79026 NM_001620 /// NM_024060 /// XM_005274240 /// XM_005274241 /// XM_005274242 /// XM_005274243 /// XM_005274244 /// XM_005274245 /// XM_005274246 /// XM_006718686 /// XM_006718687 /// XM_006718688 0007399 // nervous system development // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from sequence or structural similarity /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030315 // T-tubule // non-traceable author statement /// 0031982 // vesicle // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0042383 // sarcolemma // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097493 // structural molecule activity conferring elasticity // inferred from sequence or structural similarity 211987_at NM_001068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001068.1 /DEF=Homo sapiens topoisomerase (DNA) II beta (180kD) (TOP2B), mRNA. /FEA=CDS /GEN=TOP2B /PROD=topoisomerase (DNA) II beta (180kD) /DB_XREF=gi:11225253 /UG=Hs.75248 topoisomerase (DNA) II beta (180kD) /FL=gb:NM_001068.1 NM_001068 topoisomerase (DNA) II beta 180kDa TOP2B 7155 NM_001068 /// XM_005265427 /// XR_427287 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000819 // sister chromatid segregation // not recorded /// 0001764 // neuron migration // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // /// 0006265 // DNA topological change // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // not recorded /// 0006312 // mitotic recombination // not recorded /// 0007059 // chromosome segregation // /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0044774 // mitotic DNA integrity checkpoint // not recorded 0000792 // heterochromatin // inferred from direct assay /// 0000795 // synaptonemal complex // /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0009295 // nucleoid // not recorded /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // not recorded /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 211988_at BG289800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289800 /FEA=EST /DB_XREF=gi:13045953 /DB_XREF=est:602385095F1 /CLONE=IMAGE:4514135 /UG=Hs.332848 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 /FL=gb:NM_003079.1 BG289800 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 SMARCE1 6605 NM_003079 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000228 // nuclear chromosome // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 211989_at NM_003079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003079.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1), mRNA. /FEA=CDS /GEN=SMARCE1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily e, member 1 /DB_XREF=gi:4507088 /UG=Hs.332848 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 /FL=gb:NM_003079.1 NM_003079 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 SMARCE1 6605 NM_003079 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000228 // nuclear chromosome // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 211990_at M27487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M27487.1 /DEF=Homo sapiens MHC class II DPw3-alpha-1 chain mRNA, complete cds. /FEA=CDS /GEN=HLA-DPA1 /PROD=MHC class II DP3-alpha /DB_XREF=gi:703088 /UG=Hs.914 Human mRNA for SB classII histocompatibility antigen alpha-chain /FL=gb:M27487.1 M27487 major histocompatibility complex, class II, DP alpha 1 HLA-DPA1 3113 NM_001242524 /// NM_001242525 /// NM_033554 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 211991_s_at M27487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M27487.1 /DEF=Homo sapiens MHC class II DPw3-alpha-1 chain mRNA, complete cds. /FEA=CDS /GEN=HLA-DPA1 /PROD=MHC class II DP3-alpha /DB_XREF=gi:703088 /UG=Hs.914 Human mRNA for SB classII histocompatibility antigen alpha-chain /FL=gb:M27487.1 M27487 major histocompatibility complex, class II, DP alpha 1 HLA-DPA1 3113 NM_001242524 /// NM_001242525 /// NM_033554 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 211992_at AI445745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI445745 /FEA=EST /DB_XREF=gi:4290360 /DB_XREF=est:tj09e04.x1 /CLONE=IMAGE:2141022 /UG=Hs.184592 protein kinase, lysine deficient 1 /FL=gb:NM_018979.1 AI445745 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay 211993_at AI768512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768512 /FEA=EST /DB_XREF=gi:5235021 /DB_XREF=est:wh22g07.x1 /CLONE=IMAGE:2381532 /UG=Hs.184592 protein kinase, lysine deficient 1 /FL=gb:NM_018979.1 AI768512 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay 211994_at AI742553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742553 /FEA=EST /DB_XREF=gi:5110841 /DB_XREF=est:wg55d02.x1 /CLONE=IMAGE:2368995 /UG=Hs.184592 protein kinase, lysine deficient 1 /FL=gb:NM_018979.1 AI742553 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay 211995_x_at AL567820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567820 /FEA=EST /DB_XREF=gi:12921560 /DB_XREF=est:AL567820 /CLONE=CS0DF033YD24 (3 prime) /UG=Hs.14376 actin, gamma 1 AL567820 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 211996_s_at BG256504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG256504 /FEA=EST /DB_XREF=gi:12766320 /DB_XREF=est:602370041F1 /CLONE=IMAGE:4478098 /UG=Hs.110613 KIAA0220 protein BG256504 nuclear pore complex-interacting protein family member B4-like /// nuclear pore complex-interacting protein family member B4-like /// nuclear pore complex interacting protein pseudogene /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member B11 /// nuclear pore complex interacting protein family, member B3 /// nuclear pore complex interacting protein family, member B4 /// nuclear pore complex interacting protein family, member B5 LOC101060275 /// LOC101929910 /// LOC613037 /// NPIPA5 /// NPIPB11 /// NPIPB3 /// NPIPB4 /// NPIPB5 23117 /// 440345 /// 613037 /// 728888 /// 100132247 /// 100288332 /// 101060275 /// 101929910 NM_001135865 /// NM_001277325 /// NM_130464 /// NR_002555 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005276516 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006721108 /// XM_006721110 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006726610 /// XM_006726615 /// XM_006726626 /// XM_006726627 /// XM_006726628 /// XR_433240 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 211997_x_at NM_005324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005324.1 /DEF=Homo sapiens H3 histone, family 3B (H3.3B) (H3F3B), mRNA. /FEA=CDS /GEN=H3F3B /PROD=H3 histone, family 3B (H3.3B) /DB_XREF=gi:4885384 /UG=Hs.180877 H3 histone, family 3B (H3.3B) /FL=gb:NM_005324.1 NM_005324 H3 histone, family 3A /// H3 histone, family 3B (H3.3B) /// microRNA 4738 H3F3A /// H3F3B /// MIR4738 3020 /// 3021 /// 100616282 NM_002107 /// NM_005324 /// NR_039892 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211998_at AW138159 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138159 /FEA=EST /DB_XREF=gi:6142559 /DB_XREF=est:UI-H-BI1-acy-d-03-0-UI.s1 /CLONE=IMAGE:2716060 /UG=Hs.180877 H3 histone, family 3B (H3.3B) /FL=gb:NM_005324.1 AW138159 H3 histone, family 3A /// H3 histone, family 3B (H3.3B) /// microRNA 4738 H3F3A /// H3F3B /// MIR4738 3020 /// 3021 /// 100616282 NM_002107 /// NM_005324 /// NR_039892 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 211999_at Z48950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z48950 /DEF=H.sapiens hH3.3B gene for histone H3.3 /FEA=mRNA /DB_XREF=gi:761715 /UG=Hs.180877 H3 histone, family 3B (H3.3B) /FL=gb:NM_005324.1 Z48950 H3 histone, family 3A /// H3 histone, family 3B (H3.3B) /// microRNA 4738 H3F3A /// H3F3B /// MIR4738 3020 /// 3021 /// 100616282 NM_002107 /// NM_005324 /// NR_039892 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212000_at AB002363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002363.1 /DEF=Human mRNA for KIAA0365 gene, partial cds. /FEA=mRNA /GEN=KIAA0365 /DB_XREF=gi:2224670 /UG=Hs.190452 KIAA0365 gene product AB002363 SURP and G patch domain containing 2 SUGP2 10147 NM_001017392 /// NM_014884 /// XR_430120 /// XR_430121 /// XR_430122 /// XR_430123 /// XR_430124 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212001_at AV738039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV738039 /FEA=EST /DB_XREF=gi:10855620 /DB_XREF=est:AV738039 /CLONE=CBFBDH07 /UG=Hs.190452 KIAA0365 gene product AV738039 SURP and G patch domain containing 2 SUGP2 10147 NM_001017392 /// NM_014884 /// XR_430120 /// XR_430121 /// XR_430122 /// XR_430123 /// XR_430124 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212002_at AL561657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL561657 /FEA=EST /DB_XREF=gi:12909302 /DB_XREF=est:AL561657 /CLONE=CS0DL008YF05 (5 prime) /UG=Hs.226770 DKFZP566C0424 protein AL561657 SUZ RNA binding domain containing 1 SZRD1 26099 NM_001114600 /// NM_001271869 /// NR_073500 /// NR_073501 /// NR_073502 /// NR_073503 212003_at BG171020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG171020 /FEA=EST /DB_XREF=gi:12677723 /DB_XREF=est:602324033F1 /CLONE=IMAGE:4427025 /UG=Hs.226770 DKFZP566C0424 protein BG171020 SUZ RNA binding domain containing 1 SZRD1 26099 NM_001114600 /// NM_001271869 /// NR_073500 /// NR_073501 /// NR_073502 /// NR_073503 212004_at AL050028 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050028.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566C0424 (from clone DKFZp566C0424); partial cds. /FEA=mRNA /GEN=DKFZp566C0424 /PROD=hypothetical protein /DB_XREF=gi:4884267 /UG=Hs.226770 DKFZP566C0424 protein AL050028 SUZ RNA binding domain containing 1 SZRD1 26099 NM_001114600 /// NM_001271869 /// NR_073500 /// NR_073501 /// NR_073502 /// NR_073503 212005_at AL582808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL582808 /FEA=EST /DB_XREF=gi:12951159 /DB_XREF=est:AL582808 /CLONE=CS0DL008YF05 (3 prime) /UG=Hs.226770 DKFZP566C0424 protein AL582808 SUZ RNA binding domain containing 1 SZRD1 26099 NM_001114600 /// NM_001271869 /// NR_073500 /// NR_073501 /// NR_073502 /// NR_073503 212006_at AU149908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149908 /FEA=EST /DB_XREF=gi:11011429 /DB_XREF=est:AU149908 /CLONE=NT2RP2000896 /UG=Hs.77495 UBX domain-containing 1 AU149908 UBX domain protein 4 UBXN4 23190 NM_014607 /// XM_006712370 0006986 // response to unfolded protein // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212007_at AI927512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927512 /FEA=EST /DB_XREF=gi:5663476 /DB_XREF=est:wo90g11.x1 /CLONE=IMAGE:2462660 /UG=Hs.77495 UBX domain-containing 1 AI927512 UBX domain protein 4 UBXN4 23190 NM_014607 /// XM_006712370 0006986 // response to unfolded protein // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212008_at N29889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N29889 /FEA=EST /DB_XREF=gi:1148409 /DB_XREF=est:yy11e11.s1 /CLONE=IMAGE:270956 /UG=Hs.77495 UBX domain-containing 1 N29889 UBX domain protein 4 UBXN4 23190 NM_014607 /// XM_006712370 0006986 // response to unfolded protein // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212009_s_at AL553320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL553320 /FEA=EST /DB_XREF=gi:12893045 /DB_XREF=est:AL553320 /CLONE=CS0DI075YG04 (5 prime) /UG=Hs.75612 stress-induced-phosphoprotein 1 (Hsp70Hsp90-organizing protein) AL553320 stress-induced phosphoprotein 1 STIP1 10963 NM_001282652 /// NM_001282653 /// NM_006819 0006950 // response to stress // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 212010_s_at AK025647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025647.1 /DEF=Homo sapiens cDNA: FLJ21994 fis, clone HEP06577, highly similar to AF103803 Homo sapiens clone H41 unknown mRNA. /FEA=mRNA /DB_XREF=gi:10438231 /UG=Hs.283690 hypothetical protein /FL=gb:NM_017548.1 AK025647 CDV3 homolog (mouse) CDV3 55573 NM_001134422 /// NM_001134423 /// NM_001282762 /// NM_001282763 /// NM_001282764 /// NM_001282765 /// NM_017548 /// XM_005247588 /// XM_005247589 /// XM_005247590 /// XM_005247591 /// XM_005247592 /// XM_005247594 0008283 // cell proliferation // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 212012_at BF342851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF342851 /FEA=EST /DB_XREF=gi:11289878 /DB_XREF=est:602015135F1 /CLONE=IMAGE:4150664 /UG=Hs.118893 Melanoma associated gene BF342851 peroxidasin homolog (Drosophila) PXDN 7837 NM_012293 /// XM_005264707 /// XM_006711896 0001960 // negative regulation of cytokine-mediated signaling pathway // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212013_at D86983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D86983.1 /DEF=Human mRNA for KIAA0230 gene, partial cds. /FEA=mRNA /GEN=KIAA0230 /DB_XREF=gi:1504039 /UG=Hs.118893 Melanoma associated gene D86983 peroxidasin homolog (Drosophila) PXDN 7837 NM_012293 /// XM_005264707 /// XM_006711896 0001960 // negative regulation of cytokine-mediated signaling pathway // non-traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212014_x_at AI493245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI493245 /FEA=EST /DB_XREF=gi:4394248 /DB_XREF=est:ti30d08.x1 /CLONE=IMAGE:2131983 /UG=Hs.169610 CD44 antigen (homing function and Indian blood group system) AI493245 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 212015_x_at BF690062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF690062 /FEA=EST /DB_XREF=gi:11975470 /DB_XREF=est:602186366T1 /CLONE=IMAGE:4298440 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) BF690062 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212016_s_at AA679988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA679988 /FEA=EST /DB_XREF=gi:2656455 /DB_XREF=est:ag51f11.s1 /CLONE=IMAGE:1126509 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) AA679988 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212017_at BF677404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF677404 /FEA=EST /DB_XREF=gi:11951299 /DB_XREF=est:602087150F1 /CLONE=IMAGE:4251205 /UG=Hs.296356 Homo sapiens mRNA; cDNA DKFZp434M162 (from clone DKFZp434M162) BF677404 family with sequence similarity 168, member B FAM168B 130074 NM_001009993 /// XM_005263591 /// XM_006712263 /// XM_006712264 /// XM_006712265 /// XM_006712266 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 212018_s_at AK000822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000822.1 /DEF=Homo sapiens cDNA FLJ20815 fis, clone ADSE01038, highly similar to AJ007398 Homo sapiens mRNA for PBK1 protein. /FEA=mRNA /DB_XREF=gi:7021134 /UG=Hs.85963 DKFZP564M182 protein AK000822 ribosomal L1 domain containing 1 RSL1D1 26156 NM_015659 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212019_at AK025446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025446.1 /DEF=Homo sapiens cDNA: FLJ21793 fis, clone HEP00466. /FEA=mRNA /DB_XREF=gi:10437961 /UG=Hs.85963 DKFZP564M182 protein AK025446 ribosomal L1 domain containing 1 RSL1D1 26156 NM_015659 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212020_s_at AU152107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152107 /FEA=EST /DB_XREF=gi:11013628 /DB_XREF=est:AU152107 /CLONE=NT2RP3000209 /UG=Hs.80976 antigen identified by monoclonal antibody Ki-67 AU152107 marker of proliferation Ki-67 MKI67 4288 NM_001145966 /// NM_002417 /// XM_006717864 0006259 // DNA metabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212021_s_at AU132185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU132185 /FEA=EST /DB_XREF=gi:10992539 /DB_XREF=est:AU132185 /CLONE=NT2RP3003952 /UG=Hs.80976 antigen identified by monoclonal antibody Ki-67 AU132185 marker of proliferation Ki-67 MKI67 4288 NM_001145966 /// NM_002417 /// XM_006717864 0006259 // DNA metabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212022_s_at BF001806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001806 /FEA=EST /DB_XREF=gi:10702081 /DB_XREF=est:7g93e04.x1 /CLONE=IMAGE:3314046 /UG=Hs.80976 antigen identified by monoclonal antibody Ki-67 BF001806 marker of proliferation Ki-67 MKI67 4288 NM_001145966 /// NM_002417 /// XM_006717864 0006259 // DNA metabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212023_s_at AU147044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147044 /FEA=EST /DB_XREF=gi:11008565 /DB_XREF=est:AU147044 /CLONE=HEMBB1002259 /UG=Hs.80976 antigen identified by monoclonal antibody Ki-67 AU147044 marker of proliferation Ki-67 MKI67 4288 NM_001145966 /// NM_002417 /// XM_006717864 0006259 // DNA metabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212024_x_at U80184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80184 /DEF=Homo sapiens FLII gene, complete cds /FEA=mRNA /DB_XREF=gi:2138289 /UG=Hs.83849 flightless I (Drosophila) homolog U80184 flightless I homolog (Drosophila) FLII 2314 NM_001256264 /// NM_001256265 /// NM_002018 /// XM_005256555 /// XM_005256556 /// XM_005256558 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212025_s_at BG421186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG421186 /FEA=EST /DB_XREF=gi:13327692 /DB_XREF=est:602451665F1 /CLONE=IMAGE:4589873 /UG=Hs.83849 flightless I (Drosophila) homolog BG421186 flightless I homolog (Drosophila) FLII 2314 NM_001256264 /// NM_001256265 /// NM_002018 /// XM_005256555 /// XM_005256556 /// XM_005256558 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212026_s_at BE646386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646386 /FEA=EST /DB_XREF=gi:9970697 /DB_XREF=est:7e86a02.x1 /CLONE=IMAGE:3292010 /UG=Hs.325530 KIAA1067 protein BE646386 exocyst complex component 7 EXOC7 23265 NM_001013839 /// NM_001145297 /// NM_001145298 /// NM_001145299 /// NM_001282313 /// NM_001282314 /// NM_015219 /// XM_006721786 /// XM_006721787 /// XM_006721788 /// XM_006721789 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212027_at AI925305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI925305 /FEA=EST /DB_XREF=gi:5661269 /DB_XREF=est:wn02f07.x1 /CLONE=IMAGE:2444293 /UG=Hs.180789 S164 protein AI925305 RNA binding motif protein 25 RBM25 58517 NM_021239 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212028_at BE466128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE466128 /FEA=EST /DB_XREF=gi:9511903 /DB_XREF=est:hy10f03.x1 /CLONE=IMAGE:3196925 /UG=Hs.180789 S164 protein BE466128 RNA binding motif protein 25 RBM25 58517 NM_021239 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212029_s_at U79287 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79287.1 /DEF=Human clone 23867 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710265 /UG=Hs.19555 prostate tumor over expressed gene 1 U79287 uncharacterized LOC101928378 LOC101928378 101928378 NR_110730 /// XR_244005 /// XR_248576 /// XR_253899 212030_at BG251218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG251218 /FEA=EST /DB_XREF=gi:12761034 /DB_XREF=est:602365841F1 /CLONE=IMAGE:4473899 /UG=Hs.180789 S164 protein BG251218 RNA binding motif protein 25 RBM25 58517 NM_021239 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212031_at AV757384 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV757384 /FEA=EST /DB_XREF=gi:10915232 /DB_XREF=est:AV757384 /CLONE=BMFAXE02 /UG=Hs.180789 S164 protein AV757384 RNA binding motif protein 25 RBM25 58517 NM_021239 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212032_s_at AL046054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046054 /FEA=EST /DB_XREF=gi:5936153 /DB_XREF=est:DKFZp434D2072_r1 /CLONE=DKFZp434D2072 /UG=Hs.19555 prostate tumor over expressed gene 1 AL046054 prostate tumor overexpressed 1 PTOV1 53635 NM_017432 /// XM_005258998 /// XM_005258999 /// XM_005259000 /// XM_006723244 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 212033_at BF055107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055107 /FEA=EST /DB_XREF=gi:10809003 /DB_XREF=est:7j75a05.x1 /CLONE=IMAGE:3392240 /UG=Hs.180789 S164 protein BF055107 RNA binding motif protein 25 RBM25 58517 NM_021239 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212034_s_at AB028990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028990.1 /DEF=Homo sapiens mRNA for KIAA1067 protein, partial cds. /FEA=mRNA /GEN=KIAA1067 /PROD=KIAA1067 protein /DB_XREF=gi:5689470 /UG=Hs.325530 KIAA1067 protein AB028990 exocyst complex component 7 EXOC7 23265 NM_001013839 /// NM_001145297 /// NM_001145298 /// NM_001145299 /// NM_001282313 /// NM_001282314 /// NM_015219 /// XM_006721786 /// XM_006721787 /// XM_006721788 /// XM_006721789 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212035_s_at AI817079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817079 /FEA=EST /DB_XREF=gi:5436158 /DB_XREF=est:wj76g02.x1 /CLONE=IMAGE:2408786 /UG=Hs.325530 KIAA1067 protein AI817079 exocyst complex component 7 EXOC7 23265 NM_001013839 /// NM_001145297 /// NM_001145298 /// NM_001145299 /// NM_001282313 /// NM_001282314 /// NM_015219 /// XM_006721786 /// XM_006721787 /// XM_006721788 /// XM_006721789 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212036_s_at AW152664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW152664 /FEA=EST /DB_XREF=gi:6200564 /DB_XREF=est:xf77g02.x1 /CLONE=IMAGE:2624114 /UG=Hs.44499 pinin, desmosome associated protein AW152664 pinin, desmosome associated protein PNN 5411 NM_002687 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212037_at BF508848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508848 /FEA=EST /DB_XREF=gi:11592146 /DB_XREF=est:UI-H-BI4-aor-e-06-0-UI.s1 /CLONE=IMAGE:3085907 /UG=Hs.44499 pinin, desmosome associated protein BF508848 pinin, desmosome associated protein PNN 5411 NM_002687 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212038_s_at AL515918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515918 /FEA=EST /DB_XREF=gi:12779411 /DB_XREF=est:AL515918 /CLONE=CS0DA001YJ18 (3 prime) /UG=Hs.149155 voltage-dependent anion channel 1 AL515918 voltage-dependent anion channel 1 VDAC1 7416 NM_003374 /// NR_036624 /// NR_036625 /// XM_005272075 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0046930 // pore complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008308 // voltage-gated anion channel activity // inferred from sequence or structural similarity /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 212039_x_at BG339228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG339228 /FEA=EST /DB_XREF=gi:13145666 /DB_XREF=est:602437093F1 /CLONE=IMAGE:4555102 /UG=Hs.119598 ribosomal protein L3 BG339228 RNA, U86 small nucleolar /// ribosomal protein L3 /// small nucleolar RNA, C/D box 83B RNU86 /// RPL3 /// SNORD83B 6122 /// 116936 /// 116938 NM_000967 /// NM_001033853 /// NR_000026 /// NR_000028 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212040_at BG249599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG249599 /FEA=EST /DB_XREF=gi:12759426 /DB_XREF=est:602319692F1 /CLONE=IMAGE:4414895 /UG=Hs.110771 Homo sapiens cDNA: FLJ21904 fis, clone HEP03585 BG249599 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 212041_at AL566172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566172 /FEA=EST /DB_XREF=gi:12918279 /DB_XREF=est:AL566172 /CLONE=CS0DF022YE19 (3 prime) /UG=Hs.106876 ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D AL566172 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 ATP6V0D1 9114 NM_004691 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // non-traceable author statement /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 212042_x_at BG389744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG389744 /FEA=EST /DB_XREF=gi:13283180 /DB_XREF=est:602415111F1 /CLONE=IMAGE:4523499 /UG=Hs.153 ribosomal protein L7 BG389744 ribosomal protein L7 RPL7 6129 NM_000971 /// XM_006716463 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212043_at W72053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W72053 /FEA=EST /DB_XREF=gi:1382323 /DB_XREF=est:zd66e04.s1 /CLONE=IMAGE:345630 /UG=Hs.110771 Homo sapiens cDNA: FLJ21904 fis, clone HEP03585 W72053 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 212044_s_at BE737027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE737027 /FEA=EST /DB_XREF=gi:10151019 /DB_XREF=est:601306794F1 /CLONE=IMAGE:3641231 /UG=Hs.76064 ribosomal protein L27a BE737027 ribosomal protein L27a RPL27A 6157 NM_000990 /// NM_032650 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212045_at N32761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32761 /FEA=EST /DB_XREF=gi:1153160 /DB_XREF=est:yw91b08.s1 /CLONE=IMAGE:259575 /UG=Hs.78979 Golgi apparatus protein 1 N32761 golgi glycoprotein 1 GLG1 2734 NM_001145666 /// NM_001145667 /// NM_012201 /// NR_027264 /// NR_027265 0007596 // blood coagulation // traceable author statement /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060349 // bone morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 212046_x_at X60188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X60188.1 /DEF=Human ERK1 mRNA for protein serinethreonine kinase. /FEA=mRNA /GEN=ERK1 /PROD=protein serinethreonine kinase /DB_XREF=gi:31220 /UG=Hs.861 mitogen-activated protein kinase 3 X60188 mitogen-activated protein kinase 3 MAPK3 5595 NM_001040056 /// NM_001109891 /// NM_002746 /// XR_243293 0000165 // MAPK cascade // non-traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0033129 // positive regulation of histone phosphorylation // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072584 // caveolin-mediated endocytosis // traceable author statement /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement /// 2000657 // negative regulation of apolipoprotein binding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005901 // caveola // traceable author statement /// 0005925 // focal adhesion // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // non-traceable author statement /// 0004707 // MAP kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction 212047_s_at AK025329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025329.1 /DEF=Homo sapiens cDNA: FLJ21676 fis, clone COL09164. /FEA=mRNA /DB_XREF=gi:10437823 /UG=Hs.7158 DKFZP566H073 protein AK025329 ring finger protein 167 RNF167 26001 NM_015528 /// XM_005256597 /// XM_005256598 /// XM_005256599 /// XM_005256601 /// XM_005256602 /// XM_005256603 /// XM_006721499 /// XM_006721500 /// XM_006721501 /// XM_006721502 0000209 // protein polyubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212048_s_at AW245400 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW245400 /FEA=EST /DB_XREF=gi:6588393 /DB_XREF=est:2822751.3prime /CLONE=IMAGE:2822751 /UG=Hs.239307 tyrosyl-tRNA synthetase AW245400 tyrosyl-tRNA synthetase YARS 8565 NM_003680 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006437 // tyrosyl-tRNA aminoacylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004831 // tyrosine-tRNA ligase activity // traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005153 // interleukin-8 receptor binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212049_at BG230612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230612 /FEA=EST /DB_XREF=gi:12725654 /DB_XREF=est:naf41b09.x1 /CLONE=IMAGE:4143329 /UG=Hs.13996 Homo sapiens cDNA: FLJ23260 fis, clone COL05804, highly similar to HSU90911 Human clone 23652 mRNA sequence BG230612 WAS/WASL interacting protein family, member 2 WIPF2 147179 NM_133264 /// XM_005257083 /// XM_005257084 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212050_at AK026913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026913.1 /DEF=Homo sapiens cDNA: FLJ23260 fis, clone COL05804, highly similar to HSU90911 Human clone 23652 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10439884 /UG=Hs.13996 Homo sapiens cDNA: FLJ23260 fis, clone COL05804, highly similar to HSU90911 Human clone 23652 mRNA sequence AK026913 WAS/WASL interacting protein family, member 2 WIPF2 147179 NM_133264 /// XM_005257083 /// XM_005257084 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212051_at AA676803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA676803 /FEA=EST /DB_XREF=gi:2657325 /DB_XREF=est:zj65b04.s1 /CLONE=IMAGE:455119 /UG=Hs.13996 Homo sapiens cDNA: FLJ23260 fis, clone COL05804, highly similar to HSU90911 Human clone 23652 mRNA sequence AA676803 WAS/WASL interacting protein family, member 2 WIPF2 147179 NM_133264 /// XM_005257083 /// XM_005257084 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212052_s_at AB014576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014576.1 /DEF=Homo sapiens mRNA for KIAA0676 protein, partial cds. /FEA=mRNA /GEN=KIAA0676 /PROD=KIAA0676 protein /DB_XREF=gi:3327165 /UG=Hs.155829 KIAA0676 protein AB014576 TBC1 domain family, member 9B (with GRAM domain) TBC1D9B 23061 NM_015043 /// NM_198868 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 212053_at AK025504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025504.1 /DEF=Homo sapiens cDNA: FLJ21851 fis, clone HEP01962. /FEA=mRNA /DB_XREF=gi:10438041 /UG=Hs.170218 KIAA0251 protein AK025504 pyridoxal-dependent decarboxylase domain-containing protein 1-like /// pyridoxal-dependent decarboxylase domain containing 1 LOC102724985 /// PDXDC1 23042 /// 102724985 NM_001285444 /// NM_001285445 /// NM_001285447 /// NM_001285448 /// NM_001285449 /// NM_001285450 /// NM_015027 /// XM_005255173 /// XM_005255174 /// XM_005255176 /// XM_006720865 /// XM_006720866 /// XM_006725223 /// XM_006725224 /// XM_006725225 /// XM_006725226 /// XM_006725227 /// XM_006725228 /// XM_006725229 /// XM_006726595 /// XM_006726596 /// XM_006726597 /// XM_006726598 /// XM_006726599 /// XM_006726600 /// XM_006726601 0008152 // metabolic process // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 212054_x_at AK026096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026096.1 /DEF=Homo sapiens cDNA: FLJ22443 fis, clone HRC09391. /FEA=mRNA /DB_XREF=gi:10438835 /UG=Hs.155829 KIAA0676 protein AK026096 TBC1 domain family, member 9B (with GRAM domain) TBC1D9B 23061 NM_015043 /// NM_198868 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 212055_at BF689173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF689173 /FEA=EST /DB_XREF=gi:11974581 /DB_XREF=est:602184834T1 /CLONE=IMAGE:4299201 /UG=Hs.22981 DKFZP586M1523 protein BF689173 tubulin polyglutamylase complex subunit 2 TPGS2 25941 NM_001271949 /// NM_001271950 /// NM_001271951 /// NM_001271952 /// NM_001271953 /// NM_001271954 /// NM_001271955 /// NM_001271956 /// NM_015476 /// XM_005258242 /// XR_243849 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 212056_at D80004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D80004.1 /DEF=Human mRNA for KIAA0182 gene, partial cds. /FEA=mRNA /GEN=KIAA0182 /DB_XREF=gi:1136423 /UG=Hs.75909 KIAA0182 protein D80004 Gse1 coiled-coil protein GSE1 23199 NM_001134473 /// NM_001278184 /// NM_014615 /// XM_005255859 /// XM_005255860 /// XM_005255861 /// XM_005255862 /// XM_005255863 /// XM_005255864 /// XM_005255865 /// XM_006721172 /// XM_006721173 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212057_at AA206161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA206161 /FEA=EST /DB_XREF=gi:1801720 /DB_XREF=est:zq55f01.s1 /CLONE=IMAGE:645529 /UG=Hs.75909 KIAA0182 protein AA206161 Gse1 coiled-coil protein GSE1 23199 NM_001134473 /// NM_001278184 /// NM_014615 /// XM_005255859 /// XM_005255860 /// XM_005255861 /// XM_005255862 /// XM_005255863 /// XM_005255864 /// XM_005255865 /// XM_006721172 /// XM_006721173 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212058_at AI184562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI184562 /FEA=EST /DB_XREF=gi:3735200 /DB_XREF=est:qd60b05.x1 /CLONE=IMAGE:1733841 /UG=Hs.7976 KIAA0332 protein AI184562 U2 snRNP-associated SURP domain containing U2SURP 23350 NM_001080415 /// XM_005247246 /// XM_005247248 /// XM_005247249 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212059_s_at AL117480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117480.1 /DEF=Homo sapiens mRNA; cDNA DKFZp727M231 (from clone DKFZp727M231); partial cds. /FEA=mRNA /GEN=DKFZp727M231 /PROD=hypothetical protein /DB_XREF=gi:5911956 /UG=Hs.168073 DKFZP727M231 protein AL117480 transient receptor potential cation channel, subfamily C, member 4 associated protein TRPC4AP 26133 NM_015638 /// NM_199368 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 212060_at AU152088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152088 /FEA=EST /DB_XREF=gi:11013609 /DB_XREF=est:AU152088 /CLONE=NT2RP3000162 /UG=Hs.7976 KIAA0332 protein AU152088 U2 snRNP-associated SURP domain containing U2SURP 23350 NM_001080415 /// XM_005247246 /// XM_005247248 /// XM_005247249 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212061_at AB002330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002330.1 /DEF=Human mRNA for KIAA0332 gene, partial cds. /FEA=mRNA /GEN=KIAA0332 /DB_XREF=gi:2224604 /UG=Hs.7976 KIAA0332 protein AB002330 U2 snRNP-associated SURP domain containing U2SURP 23350 NM_001080415 /// XM_005247246 /// XM_005247248 /// XM_005247249 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212062_at AB014511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014511.1 /DEF=Homo sapiens mRNA for KIAA0611 protein, partial cds. /FEA=mRNA /GEN=KIAA0611 /PROD=KIAA0611 protein /DB_XREF=gi:3327035 /UG=Hs.70604 ATPase, Class II, type 9A AB014511 ATPase, class II, type 9A ATP9A 10079 NM_006045 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212063_at BE903880 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE903880 /FEA=EST /DB_XREF=gi:10395551 /DB_XREF=est:601494678F1 /CLONE=IMAGE:3896970 /UG=Hs.323950 zinc finger protein 6 (CMPX1) BE903880 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 212064_x_at AI471665 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI471665 /FEA=EST /DB_XREF=gi:4333755 /DB_XREF=est:tl99b10.x1 /CLONE=IMAGE:2155195 /UG=Hs.7647 MYC-associated zinc finger protein (purine-binding transcription factor) AI471665 MYC-associated zinc finger protein (purine-binding transcription factor) MAZ 4150 NM_001042539 /// NM_001276275 /// NM_001276276 /// NM_002383 /// NR_074080 /// XM_006721047 /// XM_006721048 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212065_s_at AW502434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW502434 /FEA=EST /DB_XREF=gi:7116911 /DB_XREF=est:UI-HF-BR0p-ajs-g-03-0-UI.r1 /CLONE=IMAGE:3075652 /UG=Hs.180948 KIAA0729 protein AW502434 ubiquitin specific peptidase 34 USP34 9736 NM_014709 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0001671 // ATPase activator activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 212066_s_at AB018272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018272.1 /DEF=Homo sapiens mRNA for KIAA0729 protein, partial cds. /FEA=mRNA /GEN=KIAA0729 /PROD=KIAA0729 protein /DB_XREF=gi:3882178 /UG=Hs.180948 KIAA0729 protein AB018272 ubiquitin specific peptidase 34 USP34 9736 NM_014709 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0001671 // ATPase activator activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 212067_s_at AL573058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL573058 /FEA=EST /DB_XREF=gi:12931931 /DB_XREF=est:AL573058 /CLONE=CS0DI014YC05 (3 prime) /UG=Hs.1279 complement component 1, r subcomponent AL573058 complement component 1, r subcomponent C1R 715 NM_001733 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 212068_s_at AB011087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011087.1 /DEF=Homo sapiens mRNA for KIAA0515 protein, partial cds. /FEA=mRNA /GEN=KIAA0515 /PROD=KIAA0515 protein /DB_XREF=gi:3043553 /UG=Hs.108945 KIAA0515 protein AB011087 proline-rich coiled-coil 2B PRRC2B 84726 NM_013318 /// NM_032640 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212069_s_at AK026025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026025.1 /DEF=Homo sapiens cDNA: FLJ22372 fis, clone HRC06695. /FEA=mRNA /DB_XREF=gi:10438733 /UG=Hs.108945 KIAA0515 protein AK026025 proline-rich coiled-coil 2B PRRC2B 84726 NM_013318 /// NM_032640 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212070_at AL554008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL554008 /FEA=EST /DB_XREF=gi:12894377 /DB_XREF=est:AL554008 /CLONE=CS0DI079YN13 (5 prime) /UG=Hs.6527 G protein-coupled receptor 56 AL554008 G protein-coupled receptor 56 GPR56 9289 NM_001145770 /// NM_001145771 /// NM_001145772 /// NM_001145773 /// NM_001145774 /// NM_001290142 /// NM_001290143 /// NM_001290144 /// NM_005682 /// NM_201524 /// NM_201525 /// XM_005256237 /// XM_005256238 /// XM_005256239 /// XM_005256240 /// XM_005256241 /// XM_005256242 /// XM_005256243 /// XM_005256244 /// XM_005256245 /// XM_005256246 /// XM_005256247 /// XM_005256248 /// XM_005256249 /// XM_005256251 /// XM_005256252 /// XM_005256253 /// XM_005256254 /// XM_005256255 /// XM_006721338 /// XM_006721339 /// XM_006721340 /// XM_006721341 /// XM_006721342 /// XM_006721343 /// XM_006721344 /// XM_006721345 /// XM_006721346 /// XM_006721347 0001525 // angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010573 // vascular endothelial growth factor production // inferred from direct assay /// 0021801 // cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from direct assay /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097451 // glial limiting end-foot // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0050840 // extracellular matrix binding // inferred from sequence or structural similarity 212071_s_at BE968833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE968833 /FEA=EST /DB_XREF=gi:10579538 /DB_XREF=est:601649861F1 /CLONE=IMAGE:3933782 /UG=Hs.324648 Homo sapiens cDNA FLJ13700 fis, clone PLACE2000216, highly similar to SPECTRIN BETA CHAIN, BRAIN BE968833 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212072_s_at AL049761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049761 /DEF=Human DNA sequence from clone RP5-863C7 on chromosome 20p12.3-13. Contains the CSNK2A1 gene for casein kinase 2 alpha 1 polypeptide (EC 2.7.1.37), ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:5738437 /UG=Hs.155140 casein kinase 2, alpha 1 polypeptide AL049761 casein kinase 2, alpha 1 polypeptide CSNK2A1 1457 NM_001895 /// NM_177559 /// NM_177560 /// XM_006723548 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // traceable author statement /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005956 // protein kinase CK2 complex // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement 212073_at AI631874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI631874 /FEA=EST /DB_XREF=gi:4683204 /DB_XREF=est:wa37b10.x1 /CLONE=IMAGE:2300251 /UG=Hs.155140 casein kinase 2, alpha 1 polypeptide AI631874 casein kinase 2, alpha 1 polypeptide CSNK2A1 1457 NM_001895 /// NM_177559 /// NM_177560 /// XM_006723548 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // traceable author statement /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005956 // protein kinase CK2 complex // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement 212074_at BE972774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE972774 /FEA=EST /DB_XREF=gi:10586110 /DB_XREF=est:601652004F1 /CLONE=IMAGE:3935281 /UG=Hs.7531 KIAA0810 protein BE972774 Sad1 and UNC84 domain containing 1 SUN1 23353 NM_001130965 /// NM_001171944 /// NM_001171945 /// NM_001171946 /// NM_025154 0006810 // transport // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from genetic interaction /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from mutant phenotype /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation 212075_s_at AI161318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI161318 /FEA=EST /DB_XREF=gi:3694562 /DB_XREF=est:qb66g02.x1 /CLONE=IMAGE:1705106 /UG=Hs.155140 casein kinase 2, alpha 1 polypeptide AI161318 casein kinase 2, alpha 1 polypeptide CSNK2A1 1457 NM_001895 /// NM_177559 /// NM_177560 /// XM_006723548 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // traceable author statement /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005956 // protein kinase CK2 complex // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement 212076_at AI701430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI701430 /FEA=EST /DB_XREF=gi:4989330 /DB_XREF=est:we29h08.x1 /CLONE=IMAGE:2342559 /UG=Hs.199160 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) /FL=gb:L04284.1 gb:NM_005933.1 AI701430 lysine (K)-specific methyltransferase 2A KMT2A 4297 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212077_at AL583520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583520 /FEA=EST /DB_XREF=gi:12952562 /DB_XREF=est:AL583520 /CLONE=CS0DC024YE13 (5 prime) /UG=Hs.182183 Homo sapiens mRNA for caldesmon, 3 UTR AL583520 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 212078_s_at AA704766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA704766 /FEA=EST /DB_XREF=gi:2714684 /DB_XREF=est:zj34h05.s1 /CLONE=IMAGE:452217 /UG=Hs.199160 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) /FL=gb:L04284.1 gb:NM_005933.1 AA704766 lysine (K)-specific methyltransferase 2A KMT2A 4297 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212079_s_at AA715041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA715041 /FEA=EST /DB_XREF=gi:2727315 /DB_XREF=est:nx94c09.s1 /CLONE=IMAGE:1269904 /UG=Hs.199160 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) /FL=gb:L04284.1 gb:NM_005933.1 AA715041 lysine (K)-specific methyltransferase 2A KMT2A 4297 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212080_at AV714029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV714029 /FEA=EST /DB_XREF=gi:10795546 /DB_XREF=est:AV714029 /CLONE=DCBCDA03 /UG=Hs.199160 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) /FL=gb:L04284.1 gb:NM_005933.1 AV714029 lysine (K)-specific methyltransferase 2A KMT2A 4297 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212081_x_at AF129756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF129756 /DEF=Homo sapiens MSH55 gene, partial cds; and CLIC1, DDAH, G6b, G6c, G5b, G6d, G6e, G6f, BAT5, G5b, CSK2B, BAT4, G4, Apo M, BAT3, BAT2, AIF-1, 1C7, LST-1, LTB, TNF, and LTA genes, complete cds /FEA=mRNA_20 /DB_XREF=gi:4337095 /UG=Hs.25911 HLA-B associated transcript-2 AF129756 proline-rich coiled-coil 2A PRRC2A 7916 NM_004638 /// NM_080686 /// XM_006715191 /// XM_006725507 /// XM_006725508 /// XM_006725723 /// XM_006725724 /// XM_006725833 /// XM_006725834 /// XM_006725922 /// XM_006726023 /// XM_006726024 /// XM_006726111 /// XM_006726112 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212082_s_at BE734356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE734356 /FEA=EST /DB_XREF=gi:10148348 /DB_XREF=est:601565603F1 /CLONE=IMAGE:3840385 /UG=Hs.77385 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle BE734356 myosin, light chain 6, alkali, smooth muscle and non-muscle MYL6 4637 NM_021019 /// NM_079423 /// NM_079425 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071564 // npBAF complex // inferred from electronic annotation /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from electronic annotation /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0031492 // nucleosomal DNA binding // inferred from direct assay 212083_at BG170659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG170659 /FEA=EST /DB_XREF=gi:12677362 /DB_XREF=est:602323531F1 /CLONE=IMAGE:4426926 /UG=Hs.226138 Homo sapiens mRNA; cDNA DKFZp566H2446 (from clone DKFZp566H2446) BG170659 testis expressed 261 TEX261 113419 NM_144582 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212084_at AV759552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV759552 /FEA=EST /DB_XREF=gi:10917400 /DB_XREF=est:AV759552 /CLONE=MDSCBH06 /UG=Hs.226138 Homo sapiens mRNA; cDNA DKFZp566H2446 (from clone DKFZp566H2446) AV759552 testis expressed 261 TEX261 113419 NM_144582 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212085_at AA916851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA916851 /FEA=EST /DB_XREF=gi:3056243 /DB_XREF=est:on10g02.s1 /CLONE=IMAGE:1556306 /UG=Hs.164280 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 AA916851 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 SLC25A6 293 NM_001636 0006112 // energy reserve metabolic process // traceable author statement /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015866 // ADP transport // non-traceable author statement /// 0015867 // ATP transport // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005471 // ATP:ADP antiporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212086_x_at AK026584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026584.1 /DEF=Homo sapiens cDNA: FLJ22931 fis, clone KAT07501, highly similar to HSLAMAR Human mRNA for nuclear envelope protein lamin A precursor. /FEA=mRNA /DB_XREF=gi:10439468 /UG=Hs.77886 lamin AC AK026584 lamin A/C LMNA 4000 NM_001257374 /// NM_001282624 /// NM_001282625 /// NM_001282626 /// NM_005572 /// NM_170707 /// NM_170708 0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212087_s_at AL562733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL562733 /FEA=EST /DB_XREF=gi:12911445 /DB_XREF=est:AL562733 /CLONE=CS0DC020YE23 (3 prime) /UG=Hs.3426 era (E. coli G-protein homolog)-like 1 AL562733 Era-like 12S mitochondrial rRNA chaperone 1 ERAL1 26284 NM_005702 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212088_at BF570122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF570122 /FEA=EST /DB_XREF=gi:11643834 /DB_XREF=est:602185972T1 /CLONE=IMAGE:4310632 /UG=Hs.75353 KIAA0123 protein BF570122 peptidase (mitochondrial processing) alpha PMPCA 23203 NM_001282944 /// NM_001282946 /// NM_015160 /// XM_005266059 0006508 // proteolysis // traceable author statement /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212089_at M13452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M13452.1 /DEF=Human lamin A mRNA, 3end. /FEA=mRNA /DB_XREF=gi:186838 /UG=Hs.77886 lamin AC M13452 lamin A/C LMNA 4000 NM_001257374 /// NM_001282624 /// NM_001282625 /// NM_001282626 /// NM_005572 /// NM_170707 /// NM_170708 0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212090_at AL571424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL571424 /FEA=EST /DB_XREF=gi:12928706 /DB_XREF=est:AL571424 /CLONE=CS0DI023YH14 (3 prime) /UG=Hs.101067 GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 AL571424 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) GRINA 2907 NM_000837 /// NM_001009184 /// XM_005250899 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212091_s_at AI141603 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI141603 /FEA=EST /DB_XREF=gi:3649060 /DB_XREF=est:qa90h10.x1 /CLONE=IMAGE:1694083 /UG=Hs.108885 collagen, type VI, alpha 1 AI141603 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 212092_at BE858180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE858180 /FEA=EST /DB_XREF=gi:10373121 /DB_XREF=est:7g18e04.x1 /CLONE=IMAGE:3306846 /UG=Hs.137476 KIAA1051 protein BE858180 paternally expressed 10 PEG10 23089 NM_001040152 /// NM_001172437 /// NM_001172438 /// NM_001184961 /// NM_001184962 /// NM_015068 0001890 // placenta development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212093_s_at AI695017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI695017 /FEA=EST /DB_XREF=gi:4982917 /DB_XREF=est:we45d07.x1 /CLONE=IMAGE:2344045 /UG=Hs.7946 KIAA1288 protein AI695017 microtubule associated tumor suppressor 1 MTUS1 57509 NM_001001924 /// NM_001001925 /// NM_001001927 /// NM_001001931 /// NM_001166393 /// NM_020749 /// XM_005273577 /// XM_005273578 /// XM_005273579 /// XM_005273580 /// XM_005273581 /// XM_005273582 /// XM_005273583 /// XR_247126 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 212094_at AL582836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL582836 /FEA=EST /DB_XREF=gi:12951215 /DB_XREF=est:AL582836 /CLONE=CS0DL008YO01 (3 prime) /UG=Hs.137476 KIAA1051 protein AL582836 paternally expressed 10 PEG10 23089 NM_001040152 /// NM_001172437 /// NM_001172438 /// NM_001184961 /// NM_001184962 /// NM_015068 0001890 // placenta development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212095_s_at BE552421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE552421 /FEA=EST /DB_XREF=gi:9794113 /DB_XREF=est:hw26b02.x1 /CLONE=IMAGE:3184011 /UG=Hs.7946 KIAA1288 protein BE552421 microtubule associated tumor suppressor 1 MTUS1 57509 NM_001001924 /// NM_001001925 /// NM_001001927 /// NM_001001931 /// NM_001166393 /// NM_020749 /// XM_005273577 /// XM_005273578 /// XM_005273579 /// XM_005273580 /// XM_005273581 /// XM_005273582 /// XM_005273583 /// XR_247126 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 212096_s_at AL096842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096842.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D1519 (from clone DKFZp586D1519). /FEA=mRNA /DB_XREF=gi:5524930 /UG=Hs.7946 KIAA1288 protein AL096842 microtubule associated tumor suppressor 1 MTUS1 57509 NM_001001924 /// NM_001001925 /// NM_001001927 /// NM_001001931 /// NM_001166393 /// NM_020749 /// XM_005273577 /// XM_005273578 /// XM_005273579 /// XM_005273580 /// XM_005273581 /// XM_005273582 /// XM_005273583 /// XR_247126 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 212097_at AU147399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147399 /FEA=EST /DB_XREF=gi:11008920 /DB_XREF=est:AU147399 /CLONE=MAMMA1000563 /UG=Hs.74034 Homo sapiens clone 24651 mRNA sequence AU147399 caveolin 1, caveolae protein, 22kDa CAV1 857 NM_001172895 /// NM_001172896 /// NM_001172897 /// NM_001753 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003057 // regulation of the force of heart contraction by chemical signal // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0030301 // cholesterol transport // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030857 // negative regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0031295 // T cell costimulation // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032507 // maintenance of protein location in cell // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033484 // nitric oxide homeostasis // inferred from sequence or structural similarity /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0052547 // regulation of peptidase activity // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060056 // mammary gland involution // inferred from sequence or structural similarity /// 0070836 // caveola assembly // inferred from mutant phenotype /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0072584 // caveolin-mediated endocytosis // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0005901 // caveola // non-traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005113 // patched binding // non-traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // traceable author statement /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0032947 // protein complex scaffold // traceable author statement /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 212098_at AL134724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134724 /FEA=EST /DB_XREF=gi:6602911 /DB_XREF=est:DKFZp547P246_s1 /CLONE=DKFZp547P246 /UG=Hs.4988 Homo sapiens clone 24711 mRNA sequence AL134724 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase MGAT5 4249 NM_002410 /// XM_005263666 /// XM_005263668 /// XM_005263669 /// XM_005263670 /// XM_006712534 /// XM_006712535 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030144 // alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity // non-traceable author statement 212099_at AI263909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI263909 /FEA=EST /DB_XREF=gi:3872112 /DB_XREF=est:qi08f09.x1 /CLONE=IMAGE:1855913 /UG=Hs.204354 ras homolog gene family, member B /FL=gb:NM_004040.1 AI263909 ras homolog family member B RHOB 388 NM_004040 0000910 // cytokinesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006927 // transformed cell apoptotic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019003 // GDP binding // inferred from electronic annotation 212100_s_at Z93241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z93241 /DEF=Human DNA sequence from clone 222E13 on chromosome 22. Contains three novel genes, an ATP Synthase G Chain, Mitochondrial (EC 3.6.1.34) pseudogene and the DIA1 gene for diaphorase (NADH) (cytochrome b-5 reductase)(EC 1.6.2.2). Contains ESTs, STSs,... /FEA=mRNA_5 /DB_XREF=gi:4826450 /UG=Hs.278314 hypothetical protein Z93241 polymerase (DNA-directed), delta interacting protein 3 POLDIP3 84271 NM_001278657 /// NM_032311 /// NM_178136 /// NR_103820 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212101_at AU154321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154321 /FEA=EST /DB_XREF=gi:11015842 /DB_XREF=est:AU154321 /CLONE=NT2RP4000774 /UG=Hs.301553 karyopherin alpha 6 (importin alpha 7) /FL=gb:AF060543.1 gb:NM_012316.1 AU154321 karyopherin alpha 6 (importin alpha 7) KPNA6 23633 NM_012316 /// XM_005270711 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 212102_s_at AK002111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002111.1 /DEF=Homo sapiens cDNA FLJ11249 fis, clone PLACE1008790, highly similar to Homo sapiens importin alpha 7 subunit mRNA. /FEA=mRNA /DB_XREF=gi:7023792 /UG=Hs.301553 karyopherin alpha 6 (importin alpha 7) /FL=gb:AF060543.1 gb:NM_012316.1 AK002111 karyopherin alpha 6 (importin alpha 7) KPNA6 23633 NM_012316 /// XM_005270711 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 212103_at BG403834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG403834 /FEA=EST /DB_XREF=gi:13297282 /DB_XREF=est:602419675F1 /CLONE=IMAGE:4526611 /UG=Hs.301553 karyopherin alpha 6 (importin alpha 7) /FL=gb:AF060543.1 gb:NM_012316.1 BG403834 karyopherin alpha 6 (importin alpha 7) KPNA6 23633 NM_012316 /// XM_005270711 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 212104_s_at N95026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N95026 /FEA=EST /DB_XREF=gi:1267308 /DB_XREF=est:zb45d12.s1 /CLONE=IMAGE:306551 /UG=Hs.5011 RNA binding motif protein 9 N95026 RNA binding protein, fox-1 homolog (C. elegans) 2 RBFOX2 23543 NM_001031695 /// NM_001082576 /// NM_001082577 /// NM_001082578 /// NM_001082579 /// NM_014309 /// XM_005261428 /// XM_005261429 /// XM_005261430 /// XM_005261431 /// XM_005261432 /// XM_005261433 /// XM_005261435 /// XM_005261437 /// XM_006724185 /// XM_006724186 /// XM_006724187 /// XM_006724188 /// XM_006724189 /// XM_006724190 /// XM_006724191 /// XM_006724192 /// XM_006724193 /// XM_006724194 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010724 // regulation of definitive erythrocyte differentiation // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0021942 // radial glia guided migration of Purkinje cell // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212105_s_at BF313832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF313832 /FEA=EST /DB_XREF=gi:11261901 /DB_XREF=est:601902228F1 /CLONE=IMAGE:4134942 /UG=Hs.74578 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) BF313832 DEAH (Asp-Glu-Ala-His) box helicase 9 DHX9 1660 NM_001357 /// NM_030588 /// NR_033302 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212106_at BF116183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF116183 /FEA=EST /DB_XREF=gi:10985659 /DB_XREF=est:7n78f07.x1 /CLONE=IMAGE:3570948 /UG=Hs.76591 KIAA0887 protein BF116183 Fas associated factor family member 2 FAF2 23197 NM_014613 0006986 // response to unfolded protein // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0035473 // lipase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0055102 // lipase inhibitor activity // inferred from direct assay 212107_s_at BE561014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE561014 /FEA=EST /DB_XREF=gi:9804734 /DB_XREF=est:601344618F1 /CLONE=IMAGE:3677500 /UG=Hs.74578 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) BE561014 DEAH (Asp-Glu-Ala-His) box helicase 9 DHX9 1660 NM_001357 /// NM_030588 /// NR_033302 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212108_at AB020694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020694.1 /DEF=Homo sapiens mRNA for KIAA0887 protein, partial cds. /FEA=mRNA /GEN=KIAA0887 /PROD=KIAA0887 protein /DB_XREF=gi:4240262 /UG=Hs.76591 KIAA0887 protein AB020694 Fas associated factor family member 2 FAF2 23197 NM_014613 0006986 // response to unfolded protein // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0035473 // lipase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0055102 // lipase inhibitor activity // inferred from direct assay 212109_at AI590869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI590869 /FEA=EST /DB_XREF=gi:4599917 /DB_XREF=est:tw88g03.x1 /CLONE=IMAGE:2266804 /UG=Hs.172035 hypothetical protein similar to mouse HN1 (Hematological and Neurological expressed sequence 1) AI590869 hematological and neurological expressed 1-like HN1L 90861 NM_144570 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 212110_at D31887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D31887.1 /DEF=Human mRNA for KIAA0062 gene, partial cds. /FEA=mRNA /GEN=KIAA0062 /DB_XREF=gi:505101 /UG=Hs.89868 KIAA0062 protein D31887 solute carrier family 39 (zinc transporter), member 14 SLC39A14 23516 NM_001128431 /// NM_001135153 /// NM_001135154 /// NM_015359 /// XM_005273463 /// XM_005273464 /// XM_005273465 /// XM_005273466 /// XM_006716323 /// XM_006716324 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype /// 0071578 // zinc ion transmembrane import // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 212111_at AA628051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA628051 /FEA=EST /DB_XREF=gi:2540050 /DB_XREF=est:ns67a01.s1 /CLONE=IMAGE:1188648 /UG=Hs.106823 H.sapiens gene from PAC 426I6, similar to syntaxin 7 AA628051 syntaxin 12 STX12 23673 NM_177424 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 212112_s_at AI816243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI816243 /FEA=EST /DB_XREF=gi:5431789 /DB_XREF=est:au46a11.x1 /CLONE=IMAGE:2517788 /UG=Hs.106823 H.sapiens gene from PAC 426I6, similar to syntaxin 7 AI816243 syntaxin 12 STX12 23673 NM_177424 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 212113_at AI927479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927479 /FEA=EST /DB_XREF=gi:5663443 /DB_XREF=est:wo90d06.x1 /CLONE=IMAGE:2462603 /UG=Hs.165590 ribosomal protein S13 AI927479 ataxin 7-like 3B ATXN7L3B 552889 NM_001136262 212114_at BE967207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE967207 /FEA=EST /DB_XREF=gi:11773627 /DB_XREF=est:601661094R1 /CLONE=IMAGE:3916174 /UG=Hs.165590 ribosomal protein S13 BE967207 ataxin 7-like 3B ATXN7L3B 552889 NM_001136262 212115_at AK023154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023154.1 /DEF=Homo sapiens cDNA FLJ13092 fis, clone NT2RP3002147. /FEA=mRNA /DB_XREF=gi:10434948 /UG=Hs.172035 hypothetical protein similar to mouse HN1 (Hematological and Neurological expressed sequence 1) AK023154 hematological and neurological expressed 1-like HN1L 90861 NM_144570 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 212116_at NM_006510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006510.1 /DEF=Homo sapiens ret finger protein (RFP), mRNA. /FEA=CDS /GEN=RFP /PROD=ret finger protein /DB_XREF=gi:5730008 /UG=Hs.142653 ret finger protein /FL=gb:AF230393.1 gb:J03407.1 gb:NM_006510.1 NM_006510 tripartite motif containing 27 TRIM27 5987 NM_006510 /// NM_030950 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002820 // negative regulation of adaptive immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype /// 0090281 // negative regulation of calcium ion import // inferred from mutant phenotype /// 1900041 // negative regulation of interleukin-2 secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016605 // PML body // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // traceable author statement 212117_at BF978689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF978689 /FEA=EST /DB_XREF=gi:12345904 /DB_XREF=est:602149457F2 /CLONE=IMAGE:4308014 /UG=Hs.166982 phosphatidylinositol glycan, class F BF978689 ras homolog family member Q RHOQ 23433 NM_012249 /// XM_005264229 0006184 // GTP catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0032427 // GBD domain binding // inferred from physical interaction 212118_at AL523814 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523814 /FEA=EST /DB_XREF=gi:12787307 /DB_XREF=est:AL523814 /CLONE=CS0DC003YH03 (3 prime) /UG=Hs.142653 ret finger protein /FL=gb:AF230393.1 gb:J03407.1 gb:NM_006510.1 AL523814 tripartite motif containing 27 TRIM27 5987 NM_006510 /// NM_030950 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002820 // negative regulation of adaptive immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype /// 0090281 // negative regulation of calcium ion import // inferred from mutant phenotype /// 1900041 // negative regulation of interleukin-2 secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016605 // PML body // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // traceable author statement 212119_at BF670447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF670447 /FEA=EST /DB_XREF=gi:11944342 /DB_XREF=est:602149641F1 /CLONE=IMAGE:4290707 /UG=Hs.166982 phosphatidylinositol glycan, class F BF670447 ras homolog family member Q RHOQ 23433 NM_012249 /// XM_005264229 0006184 // GTP catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0032427 // GBD domain binding // inferred from physical interaction 212120_at BE897886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE897886 /FEA=EST /DB_XREF=gi:10363799 /DB_XREF=est:601440558F1 /CLONE=IMAGE:3925214 /UG=Hs.166982 phosphatidylinositol glycan, class F BE897886 ras homolog family member Q RHOQ 23433 NM_012249 /// XM_005264229 0006184 // GTP catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0032427 // GBD domain binding // inferred from physical interaction 212121_at BE962354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962354 /FEA=EST /DB_XREF=gi:11765171 /DB_XREF=est:601655625R1 /CLONE=IMAGE:3846055 /UG=Hs.181185 DKFZP564D116 protein BE962354 tectonic family member 3 TCTN3 26123 NM_001143973 /// NM_015631 /// XM_005269690 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 212122_at AW771590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW771590 /FEA=EST /DB_XREF=gi:7703647 /DB_XREF=est:hn58g08.x1 /CLONE=IMAGE:3032126 /UG=Hs.166982 phosphatidylinositol glycan, class F AW771590 ras homolog family member Q RHOQ 23433 NM_012249 /// XM_005264229 0006184 // GTP catabolic process // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005522 // profilin binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0032427 // GBD domain binding // inferred from physical interaction 212123_at AL050022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050022.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D116 (from clone DKFZp564D116); partial cds. /FEA=mRNA /GEN=DKFZp564D116 /PROD=hypothetical protein /DB_XREF=gi:4884091 /UG=Hs.181185 DKFZP564D116 protein AL050022 tectonic family member 3 TCTN3 26123 NM_001143973 /// NM_015631 /// XM_005269690 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 212124_at AF070622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070622.1 /DEF=Homo sapiens clone 24800 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283888 /UG=Hs.7252 KIAA1224 protein AF070622 zinc finger, MIZ-type containing 1 ZMIZ1 57178 NM_020338 /// XM_005269987 /// XM_005269988 /// XM_006717923 /// XM_006717924 /// XM_006717925 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007296 // vitellogenesis // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212125_at NM_002883 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002883.1 /DEF=Homo sapiens Ran GTPase activating protein 1 (RANGAP1), mRNA. /FEA=CDS /GEN=RANGAP1 /PROD=Ran GTPase activating protein 1 /DB_XREF=gi:4506410 /UG=Hs.183800 Ran GTPase activating protein 1 /FL=gb:NM_002883.1 NM_002883 Ran GTPase activating protein 1 RANGAP1 5905 NM_001278651 /// NM_002883 /// XM_005261695 /// XM_005261696 /// XM_006724289 0000278 // mitotic cell cycle // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005098 // Ran GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212126_at BG391282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG391282 /FEA=EST /DB_XREF=gi:13284730 /DB_XREF=est:602417327F1 /CLONE=IMAGE:4536582 /UG=Hs.306000 hypothetical protein FLJ10624 BG391282 chromobox homolog 5 CBX5 23468 NM_001127321 /// NM_001127322 /// NM_012117 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from sequence or structural similarity /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation /// 0016605 // PML body // inferred from mutant phenotype /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0031618 // nuclear centromeric heterochromatin // non-traceable author statement /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity /// 1990226 // histone methyltransferase binding // inferred from physical interaction 212127_at BE379408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE379408 /FEA=EST /DB_XREF=gi:9324773 /DB_XREF=est:601237213F1 /CLONE=IMAGE:3609315 /UG=Hs.183800 Ran GTPase activating protein 1 /FL=gb:NM_002883.1 BE379408 Ran GTPase activating protein 1 RANGAP1 5905 NM_001278651 /// NM_002883 /// XM_005261695 /// XM_005261696 /// XM_006724289 0000278 // mitotic cell cycle // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005098 // Ran GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212128_s_at AW411370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW411370 /FEA=EST /DB_XREF=gi:6936911 /DB_XREF=est:fh11h11.y1 /CLONE=IMAGE:2964740 /UG=Hs.76111 dystroglycan 1 (dystrophin-associated glycoprotein 1) AW411370 dystroglycan 1 (dystrophin-associated glycoprotein 1) DAG1 1605 NM_001165928 /// NM_001177634 /// NM_001177635 /// NM_001177636 /// NM_001177637 /// NM_001177638 /// NM_001177639 /// NM_001177640 /// NM_001177641 /// NM_001177642 /// NM_001177643 /// NM_001177644 /// NM_004393 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // inferred from direct assay /// 0007016 // cytoskeletal anchoring at plasma membrane // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016340 // calcium-dependent cell-matrix adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0021682 // nerve maturation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016011 // dystroglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070938 // contractile ring // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0002162 // dystroglycan binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0015631 // tubulin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from sequence or structural similarity /// 0051393 // alpha-actinin binding // inferred from direct assay 212129_at AI589507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI589507 /FEA=EST /DB_XREF=gi:4598555 /DB_XREF=est:tm57a05.x1 /CLONE=IMAGE:2162192 /UG=Hs.83724 hypothetical protein MGC5466 AI589507 non imprinted in Prader-Willi/Angelman syndrome 2 NIPA2 81614 NM_001008860 /// NM_001008892 /// NM_001008894 /// NM_001184888 /// NM_001184889 /// NM_030922 /// XM_005272546 /// XM_005272547 /// XM_005272548 /// XM_005272549 /// XM_005272550 /// XM_005272552 /// XM_005272553 /// XM_006720364 /// XM_006720365 /// XM_006720366 /// XM_006720367 /// XM_006720368 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 212130_x_at AL537707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL537707 /FEA=EST /DB_XREF=gi:12801200 /DB_XREF=est:AL537707 /CLONE=CS0DF026YP17 (5 prime) /UG=Hs.150580 putative translation initiation factor AL537707 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212131_at BG054966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG054966 /FEA=EST /DB_XREF=gi:12512220 /DB_XREF=est:nac93b07.x1 /CLONE=IMAGE:3441756 /UG=Hs.8258 DKFZP434D1335 protein BG054966 LSM14A, SCD6 homolog A (S. cerevisiae) LSM14A 26065 NM_001114093 /// NM_015578 /// XM_005258719 /// XM_005258720 /// XM_005258721 /// XM_005276948 /// XM_005276949 /// XM_005276950 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0039529 // RIG-I signaling pathway // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212132_at AL117499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117499.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D1335 (from clone DKFZp434D1335); partial cds. /FEA=mRNA /GEN=DKFZp434D1335 /PROD=hypothetical protein /DB_XREF=gi:5912003 /UG=Hs.8258 DKFZP434D1335 protein AL117499 LSM14A, SCD6 homolog A (S. cerevisiae) LSM14A 26065 NM_001114093 /// NM_015578 /// XM_005258719 /// XM_005258720 /// XM_005258721 /// XM_005276948 /// XM_005276949 /// XM_005276950 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0039529 // RIG-I signaling pathway // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212133_at AI681536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI681536 /FEA=EST /DB_XREF=gi:4891718 /DB_XREF=est:tx47e03.x1 /CLONE=IMAGE:2272732 /UG=Hs.83724 hypothetical protein MGC5466 AI681536 non imprinted in Prader-Willi/Angelman syndrome 2 NIPA2 81614 NM_001008860 /// NM_001008892 /// NM_001008894 /// NM_001184888 /// NM_001184889 /// NM_030922 /// XM_005272546 /// XM_005272547 /// XM_005272548 /// XM_005272549 /// XM_005272550 /// XM_005272552 /// XM_005272553 /// XM_006720364 /// XM_006720365 /// XM_006720366 /// XM_006720367 /// XM_006720368 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 212134_at AB014538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014538.1 /DEF=Homo sapiens mRNA for KIAA0638 protein, partial cds. /FEA=mRNA /GEN=KIAA0638 /PROD=KIAA0638 protein /DB_XREF=gi:3327089 /UG=Hs.77864 KIAA0638 protein AB014538 microRNA 6716 /// pleckstrin homology-like domain, family B, member 1 MIR6716 /// PHLDB1 23187 /// 102466719 NM_001144758 /// NM_001144759 /// NM_015157 /// NR_106773 /// XM_005271468 /// XM_005271469 /// XM_005271470 /// XM_005271471 /// XM_005271472 /// XM_005271473 /// XM_005271474 /// XM_005271475 /// XM_005271477 /// XM_005277680 /// XM_006718796 /// XM_006718797 /// XM_006718798 /// XM_006718799 /// XM_006718800 /// XM_006718801 /// XM_006718802 /// XM_006718803 /// XM_006718804 /// XR_428972 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 212135_s_at AW517686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW517686 /FEA=EST /DB_XREF=gi:7155768 /DB_XREF=est:xs86d05.x1 /CLONE=IMAGE:2776521 /UG=Hs.305923 ATPase, Ca++ transporting, plasma membrane 4 AW517686 ATPase, Ca++ transporting, plasma membrane 4 ATP2B4 493 NM_001001396 /// NM_001684 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // non-traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred by curator 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 212136_at AW517686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW517686 /FEA=EST /DB_XREF=gi:7155768 /DB_XREF=est:xs86d05.x1 /CLONE=IMAGE:2776521 /UG=Hs.305923 ATPase, Ca++ transporting, plasma membrane 4 AW517686 ATPase, Ca++ transporting, plasma membrane 4 ATP2B4 493 NM_001001396 /// NM_001684 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // non-traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred by curator 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 212137_at AV746402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV746402 /FEA=EST /DB_XREF=gi:10865849 /DB_XREF=est:AV746402 /CLONE=NPAAMH12 /UG=Hs.75874 pregnancy-associated plasma protein A AV746402 La ribonucleoprotein domain family, member 1 LARP1 23367 NM_015315 /// NM_033551 /// XM_005268404 /// XM_005268406 /// XM_005268407 /// XM_005268408 /// XM_006714775 /// XM_006714776 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031931 // TORC1 complex // inferred from direct assay 0000339 // RNA cap binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 212138_at AK021757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021757.1 /DEF=Homo sapiens cDNA FLJ11695 fis, clone HEMBA1005019, highly similar to Homo sapiens mRNA for KIAA0648 protein. /FEA=mRNA /DB_XREF=gi:10433003 /UG=Hs.31921 KIAA0648 protein AK021757 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) PDS5A 23244 NM_001100399 /// NM_001100400 /// NM_015200 /// XM_005262652 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212139_at D86973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D86973.1 /DEF=Human mRNA for KIAA0219 gene, partial cds. /FEA=mRNA /GEN=KIAA0219 /DB_XREF=gi:1504019 /UG=Hs.75354 GCN1 (general control of amino-acid synthesis 1, yeast)-like 1 D86973 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) GCN1L1 10985 NM_006836 0006412 // translation // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212140_at AB014548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014548.1 /DEF=Homo sapiens mRNA for KIAA0648 protein, partial cds. /FEA=mRNA /GEN=KIAA0648 /PROD=KIAA0648 protein /DB_XREF=gi:3327109 /UG=Hs.31921 KIAA0648 protein AB014548 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) PDS5A 23244 NM_001100399 /// NM_001100400 /// NM_015200 /// XM_005262652 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212141_at AA604621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA604621 /FEA=EST /DB_XREF=gi:2445485 /DB_XREF=est:no84b08.s1 /CLONE=IMAGE:1113495 /UG=Hs.154443 minichromosome maintenance deficient (S. cerevisiae) 4 AA604621 minichromosome maintenance complex component 4 MCM4 4173 NM_005914 /// NM_182746 /// XM_005251234 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 212142_at AI936566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI936566 /FEA=EST /DB_XREF=gi:5675436 /DB_XREF=est:wd29e06.x1 /CLONE=IMAGE:2329570 /UG=Hs.154443 minichromosome maintenance deficient (S. cerevisiae) 4 AI936566 minichromosome maintenance complex component 4 MCM4 4173 NM_005914 /// NM_182746 /// XM_005251234 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 212143_s_at BF340228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF340228 /FEA=EST /DB_XREF=gi:11286690 /DB_XREF=est:602036816F1 /CLONE=IMAGE:4185050 /UG=Hs.77326 insulin-like growth factor binding protein 3 /FL=gb:NM_000598.1 BF340228 insulin-like growth factor binding protein 3 IGFBP3 3486 NM_000598 /// NM_001013398 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from genetic interaction /// 0009968 // negative regulation of signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008160 // protein tyrosine phosphatase activator activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0046872 // metal ion binding // non-traceable author statement 212144_at AL021707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021707 /DEF=Human DNA sequence from clone RP3-508I15 on chromosome 22q12-13 Contains the gene for GTPBP1 (GTP binding protein 1), two novel genes KIAA0063 and KIAA0668, a novel gene based on ESTs and cDNA, a pseudogene similar to AOP1 (antioxidant protein 1)... /FEA=mRNA_3 /DB_XREF=gi:4582132 /UG=Hs.5898 KIAA0668 protein AL021707 Sad1 and UNC84 domain containing 2 SUN2 25777 NM_001199579 /// NM_001199580 /// NM_015374 /// XM_005261500 /// XM_005261501 0006998 // nuclear envelope organization // inferred from genetic interaction /// 0007052 // mitotic spindle organization // traceable author statement /// 0007097 // nuclear migration // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031022 // nuclear migration along microfilament // inferred from sequence or structural similarity /// 0051642 // centrosome localization // inferred from sequence or structural similarity /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034993 // SUN-KASH complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 212145_at D87453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87453.1 /DEF=Human mRNA for KIAA0264 gene, partial cds. /FEA=mRNA /GEN=KIAA0264 /DB_XREF=gi:1665794 /UG=Hs.122669 KIAA0264 protein D87453 mitochondrial ribosomal protein S27 MRPS27 23107 NM_001286748 /// NM_001286751 /// NM_015084 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212146_at AB020649 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020649.1 /DEF=Homo sapiens mRNA for KIAA0842 protein, partial cds. /FEA=mRNA /GEN=KIAA0842 /PROD=KIAA0842 protein /DB_XREF=gi:4240172 /UG=Hs.74569 KIAA0842 protein AB020649 pleckstrin homology domain containing, family M (with RUN domain) member 2 PLEKHM2 23207 NM_015164 /// XM_005245790 /// XM_005245791 0007030 // Golgi organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from direct assay 212147_at AB029012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029012.1 /DEF=Homo sapiens mRNA for KIAA1089 protein, partial cds. /FEA=mRNA /GEN=KIAA1089 /PROD=KIAA1089 protein /DB_XREF=gi:5689514 /UG=Hs.4990 KIAA1089 protein AB029012 SMG5 nonsense mediated mRNA decay factor SMG5 23381 NM_015327 /// XM_005245049 /// XM_006711248 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 212148_at AL049381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049381.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J2118 (from clone DKFZp586J2118). /FEA=mRNA /DB_XREF=gi:4500168 /UG=Hs.21851 Homo sapiens cDNA FLJ12900 fis, clone NT2RP2004321 AL049381 pre-B-cell leukemia homeobox 1 PBX1 5087 NM_001204961 /// NM_001204963 /// NM_002585 /// XM_005245228 /// XM_005245229 /// XM_005245230 /// XM_006711347 0001655 // urogenital system development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212149_at AW470003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW470003 /FEA=EST /DB_XREF=gi:7040109 /DB_XREF=est:xr27f05.x1 /CLONE=IMAGE:2761377 /UG=Hs.84087 KIAA0143 protein AW470003 EFR3 homolog A (S. cerevisiae) EFR3A 23167 NM_015137 /// XM_005250849 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation 212150_at AA805651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA805651 /FEA=EST /DB_XREF=gi:2874401 /DB_XREF=est:nz41a04.s1 /CLONE=IMAGE:1290318 /UG=Hs.84087 KIAA0143 protein AA805651 EFR3 homolog A (S. cerevisiae) EFR3A 23167 NM_015137 /// XM_005250849 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation 212151_at BF967998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF967998 /FEA=EST /DB_XREF=gi:12335213 /DB_XREF=est:602269506F1 /CLONE=IMAGE:4357777 /UG=Hs.21851 Homo sapiens cDNA FLJ12900 fis, clone NT2RP2004321 BF967998 pre-B-cell leukemia homeobox 1 PBX1 5087 NM_001204961 /// NM_001204963 /// NM_002585 /// XM_005245228 /// XM_005245229 /// XM_005245230 /// XM_006711347 0001655 // urogenital system development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212152_x_at AI679080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI679080 /FEA=EST /DB_XREF=gi:4889262 /DB_XREF=est:tu71h09.x1 /CLONE=IMAGE:2256545 /UG=Hs.123090 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 AI679080 AT rich interactive domain 1A (SWI-like) ARID1A 8289 NM_006015 /// NM_018450 /// NM_139135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003205 // cardiac chamber development // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0042766 // nucleosome mobilization // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0090544 // BAF-type complex // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from electronic annotation 212153_at AB007930 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007930.1 /DEF=Homo sapiens mRNA for KIAA0461 perotein, partial cds. /FEA=mRNA /GEN=KIAA0461 /PROD=KIAA0461 perotein /DB_XREF=gi:3413883 /UG=Hs.107088 KIAA0461 protein AB007930 pogo transposable element with ZNF domain POGZ 23126 NM_001194937 /// NM_001194938 /// NM_015100 /// NM_145796 /// NM_207171 /// XM_005244999 /// XM_005245000 /// XM_005245001 /// XM_005245003 /// XM_005245004 /// XM_005245005 /// XM_005245006 /// XM_006711237 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212154_at AI380298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI380298 /FEA=EST /DB_XREF=gi:4190151 /DB_XREF=est:tf99h06.x1 /CLONE=IMAGE:2107451 /UG=Hs.1501 syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) AI380298 syndecan 2 SDC2 6383 NM_002998 /// XM_005251019 /// XM_005251020 /// XM_006716614 0001523 // retinoid metabolic process // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction 212155_at AA085748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA085748 /FEA=EST /DB_XREF=gi:1629231 /DB_XREF=est:zk71f11.s1 /CLONE=IMAGE:488301 /UG=Hs.144904 nuclear receptor co-repressor 1 AA085748 ring finger protein 187 RNF187 149603 NM_001010858 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212156_at AA812224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA812224 /FEA=EST /DB_XREF=gi:2881835 /DB_XREF=est:ob84g11.s1 /CLONE=IMAGE:1338116 /UG=Hs.9452 KIAA0770 protein AA812224 vacuolar protein sorting 39 homolog (S. cerevisiae) VPS39 23339 NM_015289 /// XM_005254259 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212157_at BE048514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE048514 /FEA=EST /DB_XREF=gi:8365567 /DB_XREF=est:hr50a03.x1 /CLONE=IMAGE:3131884 /UG=Hs.1501 syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) BE048514 syndecan 2 SDC2 6383 NM_002998 /// XM_005251019 /// XM_005251020 /// XM_006716614 0001523 // retinoid metabolic process // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction 212158_at AL577322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL577322 /FEA=EST /DB_XREF=gi:12940338 /DB_XREF=est:AL577322 /CLONE=CS0DI085YI06 (3 prime) /UG=Hs.1501 syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) AL577322 syndecan 2 SDC2 6383 NM_002998 /// XM_005251019 /// XM_005251020 /// XM_006716614 0001523 // retinoid metabolic process // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction 212159_x_at AI125280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI125280 /FEA=EST /DB_XREF=gi:3593794 /DB_XREF=est:qd92c05.x1 /CLONE=IMAGE:1736936 /UG=Hs.19121 adaptor-related protein complex 2, alpha 2 subunit AI125280 adaptor-related protein complex 2, alpha 2 subunit AP2A2 161 NM_001242837 /// NM_012305 /// XM_006718159 /// XM_006718160 /// XR_242779 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // non-traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 212160_at AI984005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984005 /FEA=EST /DB_XREF=gi:5811224 /DB_XREF=est:wt52c06.x1 /CLONE=IMAGE:2511082 /UG=Hs.85951 exportin, tRNA (nuclear export receptor for tRNAs) /FL=gb:AF039022.1 gb:NM_007235.2 AI984005 exportin, tRNA XPOT 11260 NM_007235 0006409 // tRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation 212161_at AA994666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA994666 /FEA=EST /DB_XREF=gi:3181155 /DB_XREF=est:ou58a05.s1 /CLONE=IMAGE:1631984 /UG=Hs.19121 adaptor-related protein complex 2, alpha 2 subunit AA994666 adaptor-related protein complex 2, alpha 2 subunit AP2A2 161 NM_001242837 /// NM_012305 /// XM_006718159 /// XM_006718160 /// XR_242779 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // non-traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 212162_at AK022873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022873.1 /DEF=Homo sapiens cDNA FLJ12811 fis, clone NT2RP2002475. /FEA=mRNA /DB_XREF=gi:10434518 /UG=Hs.9873 likely homolog of rat kinase D-interacting substance of 220 kDa; KIAA1250 protein AK022873 kinase D-interacting substrate, 220kDa KIDINS220 57498 NM_020738 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 212163_at AB033076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033076.1 /DEF=Homo sapiens mRNA for KIAA1250 protein, partial cds. /FEA=mRNA /GEN=KIAA1250 /PROD=KIAA1250 protein /DB_XREF=gi:6330860 /UG=Hs.9873 likely homolog of rat kinase D-interacting substance of 220 kDa; KIAA1250 protein AB033076 kinase D-interacting substrate, 220kDa KIDINS220 57498 NM_020738 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 212164_at AL522296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL522296 /FEA=EST /DB_XREF=gi:12785789 /DB_XREF=est:AL522296 /CLONE=CS0DB008YP08 (5 prime) /UG=Hs.17481 Homo sapiens clone 24606 mRNA sequence AL522296 transmembrane protein 183A /// transmembrane protein 183B TMEM183A /// TMEM183B 92703 /// 653659 NM_001079809 /// NM_138391 /// XM_005245612 /// XR_241106 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212165_at AF070537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070537.1 /DEF=Homo sapiens clone 24606 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387894 /UG=Hs.17481 Homo sapiens clone 24606 mRNA sequence AF070537 transmembrane protein 183A /// transmembrane protein 183B TMEM183A /// TMEM183B 92703 /// 653659 NM_001079809 /// NM_138391 /// XM_005245612 /// XR_241106 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212166_at H38643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H38643 /FEA=EST /DB_XREF=gi:908142 /DB_XREF=est:yp62f02.s1 /CLONE=IMAGE:192027 /UG=Hs.172685 RAN binding protein 16 H38643 exportin 7 XPO7 23039 NM_001100161 /// NM_001100162 /// NM_015024 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005049 // nuclear export signal receptor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation 212167_s_at AK021419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021419.1 /DEF=Homo sapiens cDNA FLJ11357 fis, clone HEMBA1000201, highly similar to Homo sapiens mRNA for integrase interactor 1b protein (INI1B). /FEA=mRNA /DB_XREF=gi:10432598 /UG=Hs.159971 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 AK021419 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 SMARCB1 6598 NM_001007468 /// NM_003073 0001824 // blastocyst development // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0006281 // DNA repair // not recorded /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // not recorded /// 0015074 // DNA integration // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0039692 // single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // not recorded /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0044772 // mitotic cell cycle phase transition // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 212168_at AL514547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL514547 /FEA=EST /DB_XREF=gi:12778041 /DB_XREF=est:AL514547 /CLONE=CL0BB004ZC07 (3 prime) /UG=Hs.180895 putative brain nuclearly-targeted protein AL514547 RNA binding motif protein 12 RBM12 10137 NM_001198838 /// NM_001198840 /// NM_006047 /// NM_152838 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212169_at AL050187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050187.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1723 (from clone DKFZp586B1723). /FEA=mRNA /DB_XREF=gi:4884402 /UG=Hs.302749 FK506-binding protein 9 (63 kD) AL050187 FK506 binding protein 9, 63 kDa FKBP9 11328 NM_001284341 /// NM_001284343 /// NM_007270 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212170_at BF447705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF447705 /FEA=EST /DB_XREF=gi:11512843 /DB_XREF=est:7q94d07.x1 /CLONE=IMAGE:3706021 /UG=Hs.180895 putative brain nuclearly-targeted protein BF447705 RNA binding motif protein 12 RBM12 10137 NM_001198838 /// NM_001198840 /// NM_006047 /// NM_152838 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212171_x_at H95344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H95344 /FEA=EST /DB_XREF=gi:1102977 /DB_XREF=est:yu21b08.s1 /CLONE=IMAGE:234423 /UG=Hs.73793 vascular endothelial growth factor /FL=gb:AF214570.1 H95344 vascular endothelial growth factor A VEGFA 7422 NM_001025366 /// NM_001025367 /// NM_001025368 /// NM_001025369 /// NM_001025370 /// NM_001033756 /// NM_001171622 /// NM_001171623 /// NM_001171624 /// NM_001171625 /// NM_001171626 /// NM_001171627 /// NM_001171628 /// NM_001171629 /// NM_001171630 /// NM_001204384 /// NM_001204385 /// NM_001287044 /// NM_003376 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0002575 // basophil chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // traceable author statement /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003169 // coronary vein morphogenesis // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009409 // response to cold // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0030225 // macrophage differentiation // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0031077 // post-embryonic camera-type eye development // inferred from sequence or structural similarity /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032793 // positive regulation of CREB transcription factor activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035148 // tube formation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036303 // lymph vessel morphogenesis // inferred from sequence or structural similarity /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0040007 // growth // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043129 // surfactant homeostasis // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060319 // primitive erythrocyte differentiation // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060948 // cardiac vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090037 // positive regulation of protein kinase C signaling // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901492 // positive regulation of lymphangiogenesis // inferred from electronic annotation /// 1901727 // positive regulation of histone deacetylase activity // inferred from direct assay /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from direct assay /// 1902966 // positive regulation of protein localization to early endosome // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0001968 // fibronectin binding // inferred from direct assay /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005172 // vascular endothelial growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype /// 0038191 // neuropilin binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048018 // receptor agonist activity // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred by curator 212172_at AW277253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW277253 /FEA=EST /DB_XREF=gi:6664283 /DB_XREF=est:xq80f09.x1 /CLONE=IMAGE:2756969 /UG=Hs.171811 adenylate kinase 2 AW277253 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 212173_at AU154985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154985 /FEA=EST /DB_XREF=gi:11016506 /DB_XREF=est:AU154985 /CLONE=OVARC1000666 /UG=Hs.171811 adenylate kinase 2 AU154985 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 212174_at W02312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W02312 /FEA=EST /DB_XREF=gi:1274291 /DB_XREF=est:za08d08.r1 /CLONE=IMAGE:291951 /UG=Hs.171811 adenylate kinase 2 W02312 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 212175_s_at AL513611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL513611 /FEA=EST /DB_XREF=gi:12777105 /DB_XREF=est:AL513611 /CLONE=XCL0BB001ZB07 (3 prime) /UG=Hs.171811 adenylate kinase 2 AL513611 adenylate kinase 2 AK2 204 NM_001199199 /// NM_001625 /// NM_013411 /// NR_037591 /// NR_037592 /// XR_246248 0001889 // liver development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097226 // sperm mitochondrial sheath // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 212176_at AA902326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA902326 /FEA=EST /DB_XREF=gi:3037233 /DB_XREF=est:ok92b01.s1 /CLONE=IMAGE:1521385 /UG=Hs.18368 DKFZP564B0769 protein AA902326 PNN-interacting serine/arginine-rich protein PNISR 25957 NM_015491 /// NM_032870 /// XM_005266912 /// XM_005266913 /// XM_005266914 /// XM_005266915 /// XM_005266916 /// XM_005266917 /// XM_006715450 /// XM_006715451 /// XM_006715452 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 212177_at AW081113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW081113 /FEA=EST /DB_XREF=gi:6036265 /DB_XREF=est:xc29c08.x1 /CLONE=IMAGE:2585678 /UG=Hs.18368 DKFZP564B0769 protein AW081113 PNN-interacting serine/arginine-rich protein PNISR 25957 NM_015491 /// NM_032870 /// XM_005266912 /// XM_005266913 /// XM_005266914 /// XM_005266915 /// XM_005266916 /// XM_005266917 /// XM_006715450 /// XM_006715451 /// XM_006715452 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 212178_s_at AK022555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022555.1 /DEF=Homo sapiens cDNA FLJ12493 fis, clone NT2RM2001635, moderately similar to NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121. /FEA=mRNA /DB_XREF=gi:10434012 /UG=Hs.295112 KIAA0618 gene product AK022555 POM121 transmembrane nucleoporin C POM121C 100101267 NM_001099415 /// XM_005250082 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 212179_at AW157501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157501 /FEA=EST /DB_XREF=gi:6228902 /DB_XREF=est:au83a02.x1 /CLONE=IMAGE:2782826 /UG=Hs.18368 DKFZP564B0769 protein AW157501 PNN-interacting serine/arginine-rich protein PNISR 25957 NM_015491 /// NM_032870 /// XM_005266912 /// XM_005266913 /// XM_005266914 /// XM_005266915 /// XM_005266916 /// XM_005266917 /// XM_006715450 /// XM_006715451 /// XM_006715452 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 212180_at AK000311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000311.1 /DEF=Homo sapiens cDNA FLJ20304 fis, clone HEP06749. /FEA=mRNA /DB_XREF=gi:7020310 /UG=Hs.5613 Homo sapiens mRNA; cDNA DKFZp564E2222 (from clone DKFZp564E2222) AK000311 v-crk avian sarcoma virus CT10 oncogene homolog-like CRKL 1399 NM_005207 0000186 // activation of MAPKK activity // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007254 // JNK cascade // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048538 // thymus development // inferred from electronic annotation /// 0060017 // parathyroid gland development // inferred from electronic annotation 0005768 // endosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212181_s_at AF191654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF191654.2 /DEF=Homo sapiens diphosphoinositol polyphosphate phosphohydrolase type 2 (NUDT4) gene, partial sequence. /FEA=mRNA /DB_XREF=gi:7741064 /UG=Hs.92381 nudix (nucleoside diphosphate linked moiety X)-type motif 4 AF191654 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 2 NUDT4 /// NUDT4P1 /// NUDT4P2 11163 /// 170688 /// 440672 NM_019094 /// NM_199040 /// NR_002212 /// NR_104005 /// XM_005268595 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0019935 // cyclic-nucleotide-mediated signaling // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046831 // regulation of RNA export from nucleus // traceable author statement /// 0046907 // intracellular transport // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // traceable author statement /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 212182_at AB007956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007956.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0487. /FEA=mRNA /DB_XREF=gi:3413930 /UG=Hs.92381 nudix (nucleoside diphosphate linked moiety X)-type motif 4 AB007956 nudix (nucleoside diphosphate linked moiety X)-type motif 4 NUDT4 11163 NM_019094 /// NM_199040 /// XM_005268595 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0019935 // cyclic-nucleotide-mediated signaling // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046831 // regulation of RNA export from nucleus // traceable author statement /// 0046907 // intracellular transport // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // traceable author statement /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 212183_at AW511135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW511135 /FEA=EST /DB_XREF=gi:7149213 /DB_XREF=est:hd43g08.x1 /CLONE=IMAGE:2912318 /UG=Hs.92381 nudix (nucleoside diphosphate linked moiety X)-type motif 4 AW511135 nudix (nucleoside diphosphate linked moiety X)-type motif 4 /// nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 NUDT4 /// NUDT4P1 11163 /// 440672 NM_019094 /// NM_199040 /// NR_002212 /// XM_005268595 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0019935 // cyclic-nucleotide-mediated signaling // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046831 // regulation of RNA export from nucleus // traceable author statement /// 0046907 // intracellular transport // traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // traceable author statement /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 212184_s_at AL117407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117407.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D2050 (from clone DKFZp434D2050); partial cds. /FEA=mRNA /GEN=DKFZp434D2050 /PROD=hypothetical protein /DB_XREF=gi:5911992 /UG=Hs.109727 TAK1-binding protein 2; KIAA0733 protein AL117407 TGF-beta activated kinase 1/MAP3K7 binding protein 2 TAB2 23118 NM_001292034 /// NM_001292035 /// NM_015093 /// NM_145342 /// XM_006715403 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from direct assay 212185_x_at NM_005953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005953.1 /DEF=Homo sapiens metallothionein 2A (MT2A), mRNA. /FEA=CDS /GEN=MT2A /PROD=metallothionein 2A /DB_XREF=gi:5174763 /UG=Hs.118786 metallothionein 2A /FL=gb:NM_005953.1 NM_005953 metallothionein 2A MT2A 4502 NM_005953 0006878 // cellular copper ion homeostasis // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from direct assay /// 0036016 // cellular response to interleukin-3 // inferred from expression pattern /// 0036018 // cellular response to erythropoietin // inferred from expression pattern /// 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212186_at BE855983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE855983 /FEA=EST /DB_XREF=gi:10368561 /DB_XREF=est:7f85g11.x1 /CLONE=IMAGE:3303812 /UG=Hs.7232 acetyl-Coenzyme A carboxylase alpha /FL=gb:NM_000664.1 gb:U19822.1 BE855983 acetyl-CoA carboxylase alpha ACACA 31 NM_000664 /// NM_198834 /// NM_198835 /// NM_198836 /// NM_198837 /// NM_198838 /// NM_198839 /// XM_005257266 /// XM_005257267 /// XM_005257268 /// XM_006721853 /// XM_006725320 /// XM_006725321 /// XM_006725322 /// XR_424818 /// XR_429952 /// XR_430795 /// XR_433374 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006084 // acetyl-CoA metabolic process // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044268 // multicellular organismal protein metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from sequence or structural similarity /// 0003989 // acetyl-CoA carboxylase activity // traceable author statement /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212187_x_at NM_000954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000954.1 /DEF=Homo sapiens prostaglandin D2 synthase (21kD, brain) (PTGDS), mRNA. /FEA=CDS /GEN=PTGDS /PROD=prostaglandin D2 synthase (21kD, brain) /DB_XREF=gi:4506250 /UG=Hs.8272 prostaglandin D2 synthase (21kD, brain) /FL=gb:AY026356.1 gb:NM_000954.1 NM_000954 prostaglandin D2 synthase 21kDa (brain) PTGDS 5730 NM_000954 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004667 // prostaglandin-D synthase activity // inferred from direct assay /// 0004667 // prostaglandin-D synthase activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005501 // retinoid binding // inferred from sequence or structural similarity /// 0005504 // fatty acid binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation 212188_at AA551075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA551075 /FEA=EST /DB_XREF=gi:2321327 /DB_XREF=est:nk74h06.s1 /CLONE=IMAGE:1019291 /UG=Hs.109438 Homo sapiens clone 24775 mRNA sequence AA551075 potassium channel tetramerization domain containing 12 KCTD12 115207 NM_138444 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212189_s_at AK022874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022874.1 /DEF=Homo sapiens cDNA FLJ12812 fis, clone NT2RP2002498. /FEA=mRNA /DB_XREF=gi:10434520 /UG=Hs.108779 DKFZP586E1519 protein AK022874 component of oligomeric golgi complex 4 COG4 25839 NM_001195139 /// NM_015386 /// XM_006721174 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0048213 // Golgi vesicle prefusion complex stabilization // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212190_at AL541302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL541302 /FEA=EST /DB_XREF=gi:12872241 /DB_XREF=est:AL541302 /CLONE=CS0DE006YI10 (5 prime) /UG=Hs.21858 trinucleotide repeat containing 3 AL541302 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 SERPINE2 5270 NM_001136528 /// NM_001136530 /// NM_006216 /// NR_073116 /// XM_005246641 /// XM_005246642 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from electronic annotation /// 0010757 // negative regulation of plasminogen activation // inferred from mutant phenotype /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0010955 // negative regulation of protein processing // inferred by curator /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0021683 // cerebellar granular layer morphogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030334 // regulation of cell migration // non-traceable author statement /// 0032940 // secretion by cell // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042628 // mating plug formation // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from direct assay /// 0050974 // detection of mechanical stimulus involved in sensory perception // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061108 // seminal vesicle epithelium development // inferred from electronic annotation /// 0090331 // negative regulation of platelet aggregation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from mutant phenotype /// 0031232 // extrinsic component of external side of plasma membrane // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 212191_x_at AW574664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW574664 /FEA=EST /DB_XREF=gi:7246203 /DB_XREF=est:UI-HF-BL0-abw-d-10-0-UI.s1 /CLONE=IMAGE:3057859 /UG=Hs.180842 ribosomal protein L13 AW574664 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212192_at AI718937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI718937 /FEA=EST /DB_XREF=gi:5036193 /DB_XREF=est:as50b04.x1 /CLONE=IMAGE:2320591 /UG=Hs.109438 Homo sapiens clone 24775 mRNA sequence AI718937 potassium channel tetramerization domain containing 12 KCTD12 115207 NM_138444 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212193_s_at BE881529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE881529 /FEA=EST /DB_XREF=gi:10330305 /DB_XREF=est:601490242F1 /CLONE=IMAGE:3892546 /UG=Hs.6214 KIAA0731 protein BE881529 La ribonucleoprotein domain family, member 1 LARP1 23367 NM_015315 /// NM_033551 /// XM_005268404 /// XM_005268406 /// XM_005268407 /// XM_005268408 /// XM_006714775 /// XM_006714776 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031931 // TORC1 complex // inferred from direct assay 0000339 // RNA cap binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 212194_s_at AI418892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI418892 /FEA=EST /DB_XREF=gi:4264823 /DB_XREF=est:tf43c01.x1 /CLONE=IMAGE:2098944 /UG=Hs.79305 KIAA0255 gene product AI418892 transmembrane 9 superfamily protein member 4 TM9SF4 9777 NM_014742 /// XM_005260622 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212195_at AL049265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049265.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053). /FEA=mRNA /DB_XREF=gi:4500013 /UG=Hs.71968 Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053) AL049265 interleukin 6 signal transducer IL6ST 3572 NM_001190981 /// NM_002184 /// NM_175767 /// NR_120480 /// XM_005248496 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0002821 // positive regulation of adaptive immune response // inferred by curator /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038154 // interleukin-11-mediated signaling pathway // inferred from electronic annotation /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from genetic interaction /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070106 // interleukin-27-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070110 // ciliary neurotrophic factor receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from genetic interaction /// 0004921 // interleukin-11 receptor activity // inferred from electronic annotation /// 0004923 // leukemia inhibitory factor receptor activity // inferred from genetic interaction /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019970 // interleukin-11 binding // inferred from electronic annotation /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred by curator 212196_at AW242916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242916 /FEA=EST /DB_XREF=gi:6576686 /DB_XREF=est:xn27f03.x1 /CLONE=IMAGE:2694941 /UG=Hs.71968 Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053) AW242916 interleukin 6 signal transducer IL6ST 3572 NM_001190981 /// NM_002184 /// NM_175767 /// NR_120480 /// XM_005248496 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0002821 // positive regulation of adaptive immune response // inferred by curator /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038154 // interleukin-11-mediated signaling pathway // inferred from electronic annotation /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from genetic interaction /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from direct assay /// 0070106 // interleukin-27-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0005900 // oncostatin-M receptor complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070110 // ciliary neurotrophic factor receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0004915 // interleukin-6 receptor activity // inferred from genetic interaction /// 0004921 // interleukin-11 receptor activity // inferred from electronic annotation /// 0004923 // leukemia inhibitory factor receptor activity // inferred from genetic interaction /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019970 // interleukin-11 binding // inferred from electronic annotation /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred by curator 212197_x_at AB020671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020671.1 /DEF=Homo sapiens mRNA for KIAA0864 protein, partial cds. /FEA=mRNA /GEN=KIAA0864 /PROD=KIAA0864 protein /DB_XREF=gi:4240216 /UG=Hs.84883 KIAA0864 protein AB020671 myosin phosphatase Rho interacting protein MPRIP 23164 NM_015134 /// NM_201274 /// XM_005256563 /// XM_005256564 /// XM_006721487 /// XM_006721488 /// XM_006721489 /// XM_006721490 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 212198_s_at AL515964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515964 /FEA=EST /DB_XREF=gi:12779457 /DB_XREF=est:AL515964 /CLONE=CS0DA001YL22 (3 prime) /UG=Hs.79305 KIAA0255 gene product AL515964 transmembrane 9 superfamily protein member 4 TM9SF4 9777 NM_014742 /// XM_005260622 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212199_at AL566962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566962 /FEA=EST /DB_XREF=gi:12919867 /DB_XREF=est:AL566962 /CLONE=CS0DF026YH08 (3 prime) /UG=Hs.284281 Human putative ribosomal protein S1 mRNA AL566962 Morf4 family associated protein 1-like 1 MRFAP1L1 114932 NM_152301 /// NM_203462 /// XM_005247932 0005515 // protein binding // inferred from physical interaction 212200_at AK025933 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025933.1 /DEF=Homo sapiens cDNA: FLJ22280 fis, clone HRC03841. /FEA=mRNA /DB_XREF=gi:10438600 /UG=Hs.100729 KIAA0692 protein AK025933 ankyrin repeat and LEM domain containing 2 ANKLE2 23141 NM_015114 /// XM_005266159 /// XM_005266160 /// XM_005266161 /// XM_006719735 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007084 // mitotic nuclear envelope reassembly // inferred from mutant phenotype /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 212201_at AW274877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW274877 /FEA=EST /DB_XREF=gi:6661907 /DB_XREF=est:xm62a09.x1 /CLONE=IMAGE:2688760 /UG=Hs.100729 KIAA0692 protein AW274877 ankyrin repeat and LEM domain containing 2 ANKLE2 23141 NM_015114 /// XM_005266159 /// XM_005266160 /// XM_005266161 /// XM_006719735 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007084 // mitotic nuclear envelope reassembly // inferred from mutant phenotype /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 212202_s_at BG493972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG493972 /FEA=EST /DB_XREF=gi:13455486 /DB_XREF=est:602542252F1 /CLONE=IMAGE:4673316 /UG=Hs.16492 DKFZP564G2022 protein BG493972 transmembrane protein 87A TMEM87A 25963 NM_001110503 /// NM_001286487 /// NM_015497 /// XM_005254287 /// XM_006720468 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212203_x_at BF338947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF338947 /FEA=EST /DB_XREF=gi:11285367 /DB_XREF=est:602036012F1 /CLONE=IMAGE:4184090 /UG=Hs.182241 interferon induced transmembrane protein 3 (1-8U) BF338947 interferon induced transmembrane protein 3 IFITM3 10410 NM_021034 /// NR_049759 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212204_at AL049944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049944.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G2022 (from clone DKFZp564G2022); partial cds. /FEA=mRNA /GEN=DKFZp564G2022 /PROD=hypothetical protein /DB_XREF=gi:4884189 /UG=Hs.16492 DKFZP564G2022 protein AL049944 transmembrane protein 87A TMEM87A 25963 NM_001110503 /// NM_001286487 /// NM_015497 /// XM_005254287 /// XM_006720468 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212205_at AA534860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA534860 /FEA=EST /DB_XREF=gi:2279113 /DB_XREF=est:nf82a04.s1 /CLONE=IMAGE:926382 /UG=Hs.301005 purine-rich element binding protein B AA534860 H2A histone family, member V H2AFV 94239 NM_012412 /// NM_138635 /// NM_201436 /// NM_201516 /// NM_201517 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212206_s_at BF343852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF343852 /FEA=EST /DB_XREF=gi:11291051 /DB_XREF=est:602015531F1 /CLONE=IMAGE:4151238 /UG=Hs.301005 purine-rich element binding protein B BF343852 H2A histone family, member V H2AFV 94239 NM_012412 /// NM_138635 /// NM_201436 /// NM_201516 /// NM_201517 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212207_at BG426689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG426689 /FEA=EST /DB_XREF=gi:13333195 /DB_XREF=est:602493234F1 /CLONE=IMAGE:4607168 /UG=Hs.4084 KIAA1025 protein BG426689 mediator complex subunit 13-like MED13L 23389 NM_015335 /// XM_006719305 /// XM_006719306 /// XM_006719307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation 212208_at AK023837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023837.1 /DEF=Homo sapiens cDNA FLJ13775 fis, clone PLACE4000369, moderately similar to Homo sapiens thyroid hormone receptor-associated protein complex component TRAP240 mRNA. /FEA=mRNA /DB_XREF=gi:10435894 /UG=Hs.4084 KIAA1025 protein AK023837 mediator complex subunit 13-like MED13L 23389 NM_015335 /// XM_006719305 /// XM_006719306 /// XM_006719307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation 212209_at AL133033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133033.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586E041 (from clone DKFZp586E041); partial cds. /FEA=mRNA /GEN=DKFZp586E041 /PROD=hypothetical protein /DB_XREF=gi:6453435 /UG=Hs.4084 KIAA1025 protein AL133033 mediator complex subunit 13-like MED13L 23389 NM_015335 /// XM_006719305 /// XM_006719306 /// XM_006719307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation 212210_at BF513430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF513430 /FEA=EST /DB_XREF=gi:11598609 /DB_XREF=est:UI-H-BW1-ams-c-01-0-UI.s1 /CLONE=IMAGE:3070848 /UG=Hs.112184 DKFZP586J0619 protein BF513430 integrator complex subunit 1 INTS1 26173 NM_001080453 0001832 // blastocyst growth // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from direct assay /// 0034474 // U2 snRNA 3'-end processing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation 212211_at AI986295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI986295 /FEA=EST /DB_XREF=gi:5813572 /DB_XREF=est:wz64c09.x1 /CLONE=IMAGE:2562832 /UG=Hs.12329 KIAA0697 protein AI986295 ankyrin repeat domain 17 ANKRD17 26057 NM_001286771 /// NM_032217 /// NM_198889 /// XM_005265667 /// XM_005265671 /// XM_005265672 /// XM_005265673 0001955 // blood vessel maturation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212212_s_at BF055496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055496 /FEA=EST /DB_XREF=gi:10809392 /DB_XREF=est:7j80h12.x1 /CLONE=IMAGE:3392807 /UG=Hs.112184 DKFZP586J0619 protein BF055496 integrator complex subunit 1 INTS1 26173 NM_001080453 0001832 // blastocyst growth // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from direct assay /// 0034474 // U2 snRNA 3'-end processing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation 212213_x_at AB011139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011139.1 /DEF=Homo sapiens mRNA for KIAA0567 protein, partial cds. /FEA=mRNA /GEN=KIAA0567 /PROD=KIAA0567 protein /DB_XREF=gi:3043657 /UG=Hs.147946 optic atrophy 1 (autosomal dominant) AB011139 optic atrophy 1 (autosomal dominant) OPA1 4976 NM_015560 /// NM_130831 /// NM_130832 /// NM_130833 /// NM_130834 /// NM_130835 /// NM_130836 /// NM_130837 0000266 // mitochondrial fission // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007005 // mitochondrion organization // non-traceable author statement /// 0007007 // inner mitochondrial membrane organization // inferred from direct assay /// 0007601 // visual perception // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0090398 // cellular senescence // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212214_at BF439570 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439570 /FEA=EST /DB_XREF=gi:11452177 /DB_XREF=est:nab69b11.x1 /CLONE=IMAGE:3272805 /UG=Hs.147946 optic atrophy 1 (autosomal dominant) BF439570 optic atrophy 1 (autosomal dominant) OPA1 4976 NM_015560 /// NM_130831 /// NM_130832 /// NM_130833 /// NM_130834 /// NM_130835 /// NM_130836 /// NM_130837 0000266 // mitochondrial fission // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007005 // mitochondrion organization // non-traceable author statement /// 0007007 // inner mitochondrial membrane organization // inferred from direct assay /// 0007601 // visual perception // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0090398 // cellular senescence // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212215_at AB007896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007896.1 /DEF=Homo sapiens KIAA0436 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0436 /DB_XREF=gi:2662152 /UG=Hs.110 putative L-type neutral amino acid transporter AB007896 prolyl endopeptidase-like PREPL 9581 NM_001042385 /// NM_001042386 /// NM_001171603 /// NM_001171606 /// NM_001171613 /// NM_001171617 /// NM_006036 /// XM_005264653 /// XM_005264654 /// XM_005264655 /// XM_005264657 /// XM_005264658 /// XM_005264659 /// XM_005264660 /// XM_006712151 /// XM_006712152 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 212216_at AW000954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW000954 /FEA=EST /DB_XREF=gi:5847870 /DB_XREF=est:wr90g09.x1 /CLONE=IMAGE:2495008 /UG=Hs.110 putative L-type neutral amino acid transporter AW000954 prolyl endopeptidase-like PREPL 9581 NM_001042385 /// NM_001042386 /// NM_001171603 /// NM_001171606 /// NM_001171613 /// NM_001171617 /// NM_006036 /// XM_005264653 /// XM_005264654 /// XM_005264655 /// XM_005264657 /// XM_005264658 /// XM_005264659 /// XM_005264660 /// XM_006712151 /// XM_006712152 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 212217_at AU154782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154782 /FEA=EST /DB_XREF=gi:11016303 /DB_XREF=est:AU154782 /CLONE=NT2RP4002085 /UG=Hs.110 putative L-type neutral amino acid transporter AU154782 prolyl endopeptidase-like PREPL 9581 NM_001042385 /// NM_001042386 /// NM_001171603 /// NM_001171606 /// NM_001171613 /// NM_001171617 /// NM_006036 /// XM_005264653 /// XM_005264654 /// XM_005264655 /// XM_005264657 /// XM_005264658 /// XM_005264659 /// XM_005264660 /// XM_006712151 /// XM_006712152 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 212218_s_at AI954041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI954041 /FEA=EST /DB_XREF=gi:5746351 /DB_XREF=est:wx78h04.x1 /CLONE=IMAGE:2549815 /UG=Hs.11050 F-box only protein 9 /FL=gb:NM_012347.1 AI954041 fatty acid synthase FASN 2194 NM_004104 0001649 // osteoblast differentiation // inferred from direct assay /// 0006084 // acetyl-CoA metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004312 // fatty acid synthase activity // traceable author statement /// 0004313 // [acyl-carrier-protein] S-acetyltransferase activity // inferred from electronic annotation /// 0004314 // [acyl-carrier-protein] S-malonyltransferase activity // inferred from electronic annotation /// 0004315 // 3-oxoacyl-[acyl-carrier-protein] synthase activity // inferred from electronic annotation /// 0004316 // 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity // inferred from electronic annotation /// 0004317 // 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0004319 // enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity // inferred from electronic annotation /// 0004320 // oleoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016295 // myristoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016296 // palmitoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016297 // acyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019171 // 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0031177 // phosphopantetheine binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047117 // enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity // inferred from electronic annotation /// 0047451 // 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from electronic annotation 212219_at D38521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38521.1 /DEF=Human mRNA for KIAA0077 gene, partial cds. /FEA=mRNA /GEN=KIAA0077 /DB_XREF=gi:559329 /UG=Hs.112396 KIAA0077 protein D38521 proteasome (prosome, macropain) activator subunit 4 PSME4 23198 NM_014614 /// XM_006711969 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006281 // DNA repair // inferred from sequence or structural similarity /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from sequence or structural similarity /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 212220_at AI972268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI972268 /FEA=EST /DB_XREF=gi:5769094 /DB_XREF=est:wr32g06.x1 /CLONE=IMAGE:2489434 /UG=Hs.112396 KIAA0077 protein AI972268 proteasome (prosome, macropain) activator subunit 4 PSME4 23198 NM_014614 /// XM_006711969 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006281 // DNA repair // inferred from sequence or structural similarity /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from sequence or structural similarity /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 212221_x_at AV703259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV703259 /FEA=EST /DB_XREF=gi:10720588 /DB_XREF=est:AV703259 /CLONE=ADBCRE12 /UG=Hs.303154 popeye protein 3 AV703259 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212222_at AU143855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU143855 /FEA=EST /DB_XREF=gi:11005376 /DB_XREF=est:AU143855 /CLONE=HEMBA1000210 /UG=Hs.112396 KIAA0077 protein AU143855 proteasome (prosome, macropain) activator subunit 4 PSME4 23198 NM_014614 /// XM_006711969 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006281 // DNA repair // inferred from sequence or structural similarity /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from sequence or structural similarity /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 212223_at AI926544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI926544 /FEA=EST /DB_XREF=gi:5662508 /DB_XREF=est:wo46c12.x1 /CLONE=IMAGE:2458390 /UG=Hs.303154 popeye protein 3 AI926544 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212224_at NM_000689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000689.1 /DEF=Homo sapiens aldehyde dehydrogenase 1, soluble (ALDH1), mRNA. /FEA=CDS /GEN=ALDH1 /PROD=aldehyde dehydrogenase 1, soluble /DB_XREF=gi:4502030 /UG=Hs.76392 aldehyde dehydrogenase 1 family, member A1 /FL=gb:AF003341.1 gb:NM_000689.1 NM_000689 aldehyde dehydrogenase 1 family, member A1 ALDH1A1 216 NM_000689 0006069 // ethanol oxidation // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001758 // retinal dehydrogenase activity // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // not recorded /// 0005099 // Ras GTPase activator activity // traceable author statement /// 0005497 // androgen binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 212225_at AL516854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL516854 /FEA=EST /DB_XREF=gi:12780347 /DB_XREF=est:AL516854 /CLONE=CS0DA007YB20 (5 prime) /UG=Hs.150580 putative translation initiation factor AL516854 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212226_s_at AA628586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA628586 /FEA=EST /DB_XREF=gi:2540973 /DB_XREF=est:af39f12.s1 /CLONE=IMAGE:1034063 /UG=Hs.173717 Homo sapiens phosphatidic acid phosphatase type 2B (PPAP2B), mRNA AA628586 phosphatidic acid phosphatase type 2B PPAP2B 8613 NM_003713 /// NM_177414 0001568 // blood vessel development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008354 // germ cell migration // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044328 // canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0044329 // canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion // inferred from mutant phenotype /// 0044330 // canonical Wnt signaling pathway involved in positive regulation of wound healing // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from electronic annotation 212227_x_at W67644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W67644 /FEA=EST /DB_XREF=gi:1376515 /DB_XREF=est:zd42a07.s1 /CLONE=IMAGE:343284 /UG=Hs.150580 putative translation initiation factor W67644 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212228_s_at AC004382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004382 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-152E5 /FEA=mRNA_8 /DB_XREF=gi:3252819 /UG=Hs.4288 hypothetical protein DKFZp434K046 AC004382 coenzyme Q9 COQ9 57017 NM_020312 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 212229_s_at AK001699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001699.1 /DEF=Homo sapiens cDNA FLJ10837 fis, clone NT2RP4001260, highly similar to Homo sapiens mRNA for KIAA0875 protein. /FEA=mRNA /DB_XREF=gi:7023121 /UG=Hs.184227 F-box only protein 21 /FL=gb:AF174601.1 AK001699 F-box protein 21 FBXO21 23014 NM_015002 /// NM_033624 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 212230_at AV725664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV725664 /FEA=EST /DB_XREF=gi:10831279 /DB_XREF=est:AV725664 /CLONE=HTCAOD07 /UG=Hs.173717 Homo sapiens phosphatidic acid phosphatase type 2B (PPAP2B), mRNA AV725664 phosphatidic acid phosphatase type 2B PPAP2B 8613 NM_003713 /// NM_177414 0001568 // blood vessel development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008354 // germ cell migration // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044328 // canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0044329 // canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion // inferred from mutant phenotype /// 0044330 // canonical Wnt signaling pathway involved in positive regulation of wound healing // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from electronic annotation 212231_at AB020682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020682.1 /DEF=Homo sapiens mRNA for KIAA0875 protein, partial cds. /FEA=mRNA /GEN=KIAA0875 /PROD=KIAA0875 protein /DB_XREF=gi:4240238 /UG=Hs.184227 F-box only protein 21 /FL=gb:AF174601.1 AB020682 F-box protein 21 FBXO21 23014 NM_015002 /// NM_033624 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 212232_at AB023231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023231.1 /DEF=Homo sapiens mRNA for KIAA1014 protein, partial cds. /FEA=mRNA /GEN=KIAA1014 /PROD=KIAA1014 protein /DB_XREF=gi:4589677 /UG=Hs.6834 KIAA1014 protein AB023231 formin binding protein 4 FNBP4 23360 NM_015308 /// XM_005252833 /// XM_005252834 /// XM_006718171 /// XR_242785 /// XR_242786 /// XR_428841 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212233_at AL523076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523076 /FEA=EST /DB_XREF=gi:12786569 /DB_XREF=est:AL523076 /CLONE=CS0DC001YI12 (3 prime) /UG=Hs.82503 H.sapiens mRNA for 3UTR of unknown protein AL523076 microtubule-associated protein 1B MAP1B 4131 NM_005909 /// NM_032010 /// XM_005248507 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from direct assay /// 0016358 // dendrite development // inferred from electronic annotation /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0061162 // establishment of monopolar cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212234_at AL034550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034550 /DEF=Human DNA sequence from clone RP5-1184F4 on chromosome 20q11.1-11.23. Contains the 3 end of gene KIAA0978, two genes for novel proteins similar to nucleolar protein 4 (NOL4) (NOLP), and one or two novel genes. Contains ESTs, STSs, GSSs and three ... /FEA=mRNA_4 /DB_XREF=gi:9187334 /UG=Hs.3686 KIAA0978 protein AL034550 additional sex combs like transcriptional regulator 1 ASXL1 171023 NM_001164603 /// NM_015338 /// XM_006723727 /// XM_006723728 /// XM_006723729 /// XM_006723730 /// XM_006723731 /// XM_006723732 /// XM_006723733 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0035359 // negative regulation of peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0035517 // PR-DUB complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from sequence or structural similarity /// 0042975 // peroxisome proliferator activated receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212235_at AL575403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL575403 /FEA=EST /DB_XREF=gi:12936533 /DB_XREF=est:AL575403 /CLONE=CS0DI060YL02 (3 prime) /UG=Hs.301685 KIAA0620 protein AL575403 plexin D1 PLXND1 23129 NM_015103 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction 212236_x_at Z19574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z19574 /DEF=H.sapiens gene for cytokeratin 17 /FEA=mRNA /DB_XREF=gi:30378 /UG=Hs.2785 keratin 17 Z19574 junction plakoglobin /// keratin 17 JUP /// KRT17 3728 /// 3872 NM_000422 /// NM_002230 /// NM_021991 /// XM_005257313 /// XM_005257349 /// XM_006721871 /// XM_006721872 /// XM_006721873 /// XM_006721874 /// XM_006721875 /// XM_006721876 /// XM_006721877 /// XM_006721878 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000902 // cell morphogenesis // not recorded /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from direct assay /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003181 // atrioventricular valve morphogenesis // not recorded /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007369 // gastrulation // not recorded /// 0007398 // ectoderm development // not recorded /// 0007399 // nervous system development // not recorded /// 0008544 // epidermis development // traceable author statement /// 0016331 // morphogenesis of embryonic epithelium // not recorded /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031424 // keratinization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0043588 // skin development // not recorded /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0048599 // oocyte development // not recorded /// 0050982 // detection of mechanical stimulus // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from sequence or structural similarity /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred by curator 0005634 // nucleus // inferred from mutant phenotype /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0005916 // fascia adherens // not recorded /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071665 // gamma-catenin-TCF7L2 complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005198 // structural molecule activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005199 // structural constituent of cell wall // inferred by curator /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032395 // MHC class II receptor activity // inferred from direct assay /// 0042289 // MHC class II protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 212237_at N64780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64780 /FEA=EST /DB_XREF=gi:1212609 /DB_XREF=est:yz30f08.s1 /CLONE=IMAGE:284583 /UG=Hs.3686 KIAA0978 protein N64780 additional sex combs like transcriptional regulator 1 ASXL1 171023 NM_001164603 /// NM_015338 /// XM_006723727 /// XM_006723728 /// XM_006723729 /// XM_006723730 /// XM_006723731 /// XM_006723732 /// XM_006723733 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0035359 // negative regulation of peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0035517 // PR-DUB complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from sequence or structural similarity /// 0042975 // peroxisome proliferator activated receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212238_at AL117518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117518.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N0535 (from clone DKFZp434N0535); partial cds. /FEA=mRNA /GEN=DKFZp434N0535 /PROD=hypothetical protein /DB_XREF=gi:5912033 /UG=Hs.3686 KIAA0978 protein AL117518 additional sex combs like transcriptional regulator 1 ASXL1 171023 NM_001164603 /// NM_015338 /// XM_006723727 /// XM_006723728 /// XM_006723729 /// XM_006723730 /// XM_006723731 /// XM_006723732 /// XM_006723733 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0035359 // negative regulation of peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0035517 // PR-DUB complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from sequence or structural similarity /// 0042975 // peroxisome proliferator activated receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212239_at AI680192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI680192 /FEA=EST /DB_XREF=gi:4890374 /DB_XREF=est:tw66a10.x1 /CLONE=IMAGE:2264634 /UG=Hs.6241 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) AI680192 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) PIK3R1 5295 NM_001242466 /// NM_181504 /// NM_181523 /// NM_181524 /// XM_005248542 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046854 // phosphatidylinositol phosphorylation // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051531 // NFAT protein import into nucleus // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from sequence or structural similarity /// 0005943 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from sequence or structural similarity /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity /// 0043559 // insulin binding // inferred from direct assay /// 0043560 // insulin receptor substrate binding // inferred from sequence or structural similarity 212240_s_at AI679268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI679268 /FEA=EST /DB_XREF=gi:4889450 /DB_XREF=est:tu62e04.x1 /CLONE=IMAGE:2255646 /UG=Hs.6241 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) AI679268 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) PIK3R1 5295 NM_001242466 /// NM_181504 /// NM_181523 /// NM_181524 /// XM_005248542 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046854 // phosphatidylinositol phosphorylation // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051531 // NFAT protein import into nucleus // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from sequence or structural similarity /// 0005943 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from sequence or structural similarity /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity /// 0043559 // insulin binding // inferred from direct assay /// 0043560 // insulin receptor substrate binding // inferred from sequence or structural similarity 212241_at AI632774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI632774 /FEA=EST /DB_XREF=gi:4684104 /DB_XREF=est:wa35a11.x1 /CLONE=IMAGE:2300060 /UG=Hs.6283 DKFZP586F1918 protein AI632774 GRINL1A complex locus 1 /// myocardial zonula adherens protein /// polymerase (RNA) II (DNA directed) polypeptide M GCOM1 /// MYZAP /// POLR2M 81488 /// 145781 /// 100820829 NM_001018090 /// NM_001018091 /// NM_001018095 /// NM_001018096 /// NM_001018099 /// NM_001018100 /// NM_001018102 /// NM_001285900 /// NM_015532 /// NM_152451 /// NR_027390 /// NR_104367 /// NR_104368 /// NR_104369 /// NR_104370 /// NR_104371 0032774 // RNA biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0051685 // maintenance of ER location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0031674 // I band // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212242_at AL565074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565074 /FEA=EST /DB_XREF=gi:12916087 /DB_XREF=est:AL565074 /CLONE=CS0DN003YF20 (3 prime) /UG=Hs.75318 tubulin, alpha 1 (testis specific) AL565074 tubulin, alpha 4a TUBA4A 7277 NM_001278552 /// NM_006000 /// XM_005246832 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0002576 // platelet degranulation // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212243_at BE645501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645501 /FEA=EST /DB_XREF=gi:9969812 /DB_XREF=est:7e71d06.x1 /CLONE=IMAGE:3287915 /UG=Hs.6283 DKFZP586F1918 protein BE645501 GRINL1A complex locus 1 /// polymerase (RNA) II (DNA directed) polypeptide M GCOM1 /// POLR2M 81488 /// 145781 NM_001018090 /// NM_001018091 /// NM_001018095 /// NM_001018096 /// NM_001018099 /// NM_001018102 /// NM_001285900 /// NM_015532 /// NR_027390 /// NR_104367 /// NR_104368 /// NR_104369 /// NR_104370 /// NR_104371 0032774 // RNA biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0051685 // maintenance of ER location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0031674 // I band // inferred from electronic annotation /// 0031674 // I band // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212244_at AL050091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050091.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1918 (from clone DKFZp586F1918); partial cds. /FEA=mRNA /GEN=DKFZp586F1918 /PROD=hypothetical protein /DB_XREF=gi:4884111 /UG=Hs.6283 DKFZP586F1918 protein AL050091 GRINL1A complex locus 1 /// polymerase (RNA) II (DNA directed) polypeptide M GCOM1 /// POLR2M 81488 /// 145781 NM_001018090 /// NM_001018091 /// NM_001018095 /// NM_001018096 /// NM_001018099 /// NM_001018102 /// NM_001285900 /// NM_015532 /// NR_027390 /// NR_104367 /// NR_104368 /// NR_104369 /// NR_104370 /// NR_104371 0032774 // RNA biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0051685 // maintenance of ER location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0031674 // I band // inferred from electronic annotation /// 0031674 // I band // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212245_at AL567779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567779 /FEA=EST /DB_XREF=gi:12921478 /DB_XREF=est:AL567779 /CLONE=CS0DF034YB08 (3 prime) /UG=Hs.84775 Human transposon-like element mRNA AL567779 multiple coagulation factor deficiency 2 MCFD2 90411 NM_001171506 /// NM_001171507 /// NM_001171508 /// NM_001171509 /// NM_001171510 /// NM_001171511 /// NM_139279 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212246_at BE880828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE880828 /FEA=EST /DB_XREF=gi:10329604 /DB_XREF=est:601493261F1 /CLONE=IMAGE:3895407 /UG=Hs.84775 Human transposon-like element mRNA BE880828 multiple coagulation factor deficiency 2 MCFD2 90411 NM_001171506 /// NM_001171507 /// NM_001171508 /// NM_001171509 /// NM_001171510 /// NM_001171511 /// NM_139279 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212247_at AW008531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW008531 /FEA=EST /DB_XREF=gi:5857309 /DB_XREF=est:wv68g04.x1 /CLONE=IMAGE:2534742 /UG=Hs.84790 KIAA0225 protein AW008531 nucleoporin 205kDa NUP205 23165 NM_015135 /// XM_005250235 0000059 // protein import into nucleus, docking // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 212248_at AI886796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI886796 /FEA=EST /DB_XREF=gi:5591960 /DB_XREF=est:wk20b07.x1 /CLONE=IMAGE:2412853 /UG=Hs.243901 Homo sapiens cDNA FLJ20738 fis, clone HEP08257 AI886796 metadherin MTDH 92140 NM_178812 /// XM_005251098 /// XM_005251099 /// XM_005251100 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070830 // tight junction assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016604 // nuclear body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 212249_at AI934473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI934473 /FEA=EST /DB_XREF=gi:5673433 /DB_XREF=est:wp58d05.x1 /CLONE=IMAGE:2465961 /UG=Hs.6241 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) AI934473 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) PIK3R1 5295 NM_001242466 /// NM_181504 /// NM_181523 /// NM_181524 /// XM_005248542 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046854 // phosphatidylinositol phosphorylation // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051531 // NFAT protein import into nucleus // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from sequence or structural similarity /// 0005943 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from sequence or structural similarity /// 0043125 // ErbB-3 class receptor binding // inferred from direct assay /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity /// 0043559 // insulin binding // inferred from direct assay /// 0043560 // insulin receptor substrate binding // inferred from sequence or structural similarity 212250_at AV700332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700332 /FEA=EST /DB_XREF=gi:10302303 /DB_XREF=est:AV700332 /CLONE=GKCDIF11 /UG=Hs.243901 Homo sapiens cDNA FLJ20738 fis, clone HEP08257 AV700332 metadherin MTDH 92140 NM_178812 /// XM_005251098 /// XM_005251099 /// XM_005251100 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070830 // tight junction assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016604 // nuclear body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 212251_at AI972475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI972475 /FEA=EST /DB_XREF=gi:5769391 /DB_XREF=est:wr40b09.x1 /CLONE=IMAGE:2490137 /UG=Hs.243901 Homo sapiens cDNA FLJ20738 fis, clone HEP08257 AI972475 metadherin MTDH 92140 NM_178812 /// XM_005251098 /// XM_005251099 /// XM_005251100 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070830 // tight junction assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016604 // nuclear body // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 212252_at AA181179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA181179 /FEA=EST /DB_XREF=gi:1764664 /DB_XREF=est:zp57b04.s1 /CLONE=IMAGE:624271 /UG=Hs.108708 calciumcalmodulin-dependent protein kinase kinase 2, beta AA181179 calcium/calmodulin-dependent protein kinase kinase 2, beta CAMKK2 10645 NM_001270485 /// NM_001270486 /// NM_006549 /// NM_153499 /// NM_153500 /// NM_172214 /// NM_172215 /// NM_172216 /// NM_172226 /// XM_005253822 /// XM_005253823 /// XM_005253824 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0045859 // regulation of protein kinase activity // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212253_x_at BG253119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG253119 /FEA=EST /DB_XREF=gi:12762935 /DB_XREF=est:602363756F1 /CLONE=IMAGE:4472293 /UG=Hs.198689 KIAA0728 protein BG253119 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 212254_s_at AI798790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI798790 /FEA=EST /DB_XREF=gi:5364262 /DB_XREF=est:we92f11.x1 /CLONE=IMAGE:2348589 /UG=Hs.198689 KIAA0728 protein AI798790 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 212255_s_at AK001684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001684.1 /DEF=Homo sapiens cDNA FLJ10822 fis, clone NT2RP4001079, weakly similar to CALCIUM-TRANSPORTING ATPASE 1 (EC 3.6.1.38). /FEA=mRNA /DB_XREF=gi:7023095 /UG=Hs.106778 ATPase, Ca++ transporting, type 2C, member 1 AK001684 ATPase, Ca++ transporting, type 2C, member 1 ATP2C1 27032 NM_001001485 /// NM_001001486 /// NM_001001487 /// NM_001199179 /// NM_001199180 /// NM_001199181 /// NM_001199182 /// NM_001199183 /// NM_001199184 /// NM_001199185 /// NM_014382 /// XM_005247354 /// XM_005247355 /// XM_005247356 /// XM_005247357 /// XM_005247358 /// XM_005247359 /// XM_006713585 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from mutant phenotype /// 0030026 // cellular manganese ion homeostasis // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0032468 // Golgi calcium ion homeostasis // inferred from mutant phenotype /// 0032472 // Golgi calcium ion transport // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 0071421 // manganese ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015410 // manganese-transporting ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212256_at BE906572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE906572 /FEA=EST /DB_XREF=gi:10399901 /DB_XREF=est:601502550F1 /CLONE=IMAGE:3904092 /UG=Hs.107260 hypothetical protein DKFZp586H0623 BE906572 polypeptide N-acetylgalactosaminyltransferase 10 GALNT10 55568 NM_017540 /// NM_024564 /// NM_198321 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212257_s_at AW131754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW131754 /FEA=EST /DB_XREF=gi:6133361 /DB_XREF=est:xf34c02.x1 /CLONE=IMAGE:2619938 /UG=Hs.198296 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 AW131754 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 212258_s_at X72889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X72889.1 /DEF=H.sapiens hbrm mRNA. /FEA=mRNA /GEN=hbrm /PROD=HBRM /DB_XREF=gi:414116 /UG=Hs.198296 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 X72889 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 212259_s_at BF344265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF344265 /FEA=EST /DB_XREF=gi:11291478 /DB_XREF=est:602017327F1 /CLONE=IMAGE:4152943 /UG=Hs.8068 hematopoietic PBX-interacting protein BF344265 pre-B-cell leukemia homeobox interacting protein 1 PBXIP1 57326 NM_020524 0007275 // multicellular organismal development // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003714 // transcription corepressor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212260_at AL045800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL045800 /FEA=EST /DB_XREF=gi:5433912 /DB_XREF=est:DKFZp434G056_s1 /CLONE=DKFZp434G056 /UG=Hs.323317 trinucleotide repeat containing 15 AL045800 GRB10 interacting GYF protein 2 GIGYF2 26058 NM_001103146 /// NM_001103147 /// NM_001103148 /// NM_015575 /// NR_103492 /// NR_103493 /// NR_103494 /// NR_103495 0007631 // feeding behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050881 // musculoskeletal movement // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212261_at AB014542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014542.1 /DEF=Homo sapiens mRNA for KIAA0642 protein, partial cds. /FEA=mRNA /GEN=KIAA0642 /PROD=KIAA0642 protein /DB_XREF=gi:3327097 /UG=Hs.323317 trinucleotide repeat containing 15 AB014542 GRB10 interacting GYF protein 2 GIGYF2 26058 NM_001103146 /// NM_001103147 /// NM_001103148 /// NM_015575 /// NR_103492 /// NR_103493 /// NR_103494 /// NR_103495 0007631 // feeding behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050881 // musculoskeletal movement // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212262_at AA149639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA149639 /FEA=EST /DB_XREF=gi:1720440 /DB_XREF=est:zl39c06.s1 /CLONE=IMAGE:504298 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142419.1 gb:AF142422.1 AA149639 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212263_at AI114716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI114716 /FEA=EST /DB_XREF=gi:6360061 /DB_XREF=est:HA1315 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142419.1 gb:AF142422.1 AI114716 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212264_s_at BE645850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645850 /FEA=EST /DB_XREF=gi:9970161 /DB_XREF=est:7e77c03.x1 /CLONE=IMAGE:3288484 /UG=Hs.154978 KIAA0261 protein BE645850 wings apart-like homolog (Drosophila) WAPAL 23063 NM_015045 /// XM_006717726 /// XM_006717727 /// XM_006717728 /// XM_006717729 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from mutant phenotype /// 0045875 // negative regulation of sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212265_at AL031781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031781 /DEF=Human DNA sequence from clone 51J12 on chromosome 6q26-27. Contains the 3 part of the alternatively spliced gene for the human orthologs of mouse QKI-7 and QKI-7B (KH Domain RNA Binding proteins) and zebrafish ZKQ-1 (Quaking protein homolog). Con... /FEA=mRNA_1 /DB_XREF=gi:4038570 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142419.1 gb:AF142422.1 AL031781 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212266_s_at AW084582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW084582 /FEA=EST /DB_XREF=gi:6039734 /DB_XREF=est:wz26h03.x1 /CLONE=IMAGE:2559221 /UG=Hs.166975 splicing factor, arginineserine-rich 5 AW084582 serine/arginine-rich splicing factor 5 SRSF5 6430 NM_001039465 /// NM_006925 /// XM_005267998 /// XM_005267999 /// XM_005268000 /// XM_005268001 /// XR_429326 /// XR_429327 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 212267_at D87450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87450.1 /DEF=Human mRNA for KIAA0261 gene, partial cds. /FEA=mRNA /GEN=KIAA0261 /DB_XREF=gi:1665788 /UG=Hs.154978 KIAA0261 protein D87450 wings apart-like homolog (Drosophila) WAPAL 23063 NM_015045 /// XM_006717726 /// XM_006717727 /// XM_006717728 /// XM_006717729 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from mutant phenotype /// 0045875 // negative regulation of sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212268_at NM_030666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_030666.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 (SERPINB1), mRNA. /FEA=CDS /GEN=SERPINB1 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 1 /DB_XREF=gi:13489086 /UG=Hs.183583 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 /FL=gb:NM_030666.1 NM_030666 serpin peptidase inhibitor, clade B (ovalbumin), member 1 SERPINB1 1992 NM_030666 /// NR_073111 /// NR_073112 /// XM_006715008 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 212269_s_at AJ010089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ010089.1 /DEF=Homo sapiens mRNA for GANP protein. /FEA=mRNA /GEN=ganp /PROD=GANP protein /DB_XREF=gi:5734401 /UG=Hs.168481 minichromosome maintenance deficient (S. cerevisiae) 3-associated protein AJ010089 minichromosome maintenance complex component 3 associated protein MCM3AP 8888 NM_003906 /// XM_005261203 /// XM_005261204 /// XM_005261205 /// XM_005261206 /// XM_006724064 /// XM_006724065 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 212270_x_at BG168283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG168283 /FEA=EST /DB_XREF=gi:12674986 /DB_XREF=est:602340822F1 /CLONE=IMAGE:4448789 /UG=Hs.82202 ribosomal protein L17 BG168283 chromosome 18 open reading frame 32 /// ribosomal protein L17 /// RPL17-C18orf32 readthrough /// small nucleolar RNA, C/D box 58A /// small nucleolar RNA, C/D box 58B /// small nucleolar RNA, C/D box 58C C18orf32 /// RPL17 /// RPL17-C18orf32 /// SNORD58A /// SNORD58B /// SNORD58C 6139 /// 26790 /// 26791 /// 497661 /// 100124516 /// 100526842 NM_000985 /// NM_001035005 /// NM_001035006 /// NM_001199340 /// NM_001199341 /// NM_001199342 /// NM_001199343 /// NM_001199344 /// NM_001199345 /// NM_001199346 /// NM_001199355 /// NM_001199356 /// NR_002571 /// NR_002572 /// NR_003701 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 212271_at AA195999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA195999 /FEA=EST /DB_XREF=gi:1791623 /DB_XREF=est:zp99f06.s1 /CLONE=IMAGE:628355 /UG=Hs.324473 mitogen-activated protein kinase 1 AA195999 mitogen-activated protein kinase 1 MAPK1 5594 NM_002745 /// NM_138957 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000189 // MAPK import into nucleus // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019858 // cytosine metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0072584 // caveolin-mediated endocytosis // traceable author statement /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005901 // caveola // traceable author statement /// 0005925 // focal adhesion // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 212272_at AA813260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA813260 /FEA=EST /DB_XREF=gi:2883245 /DB_XREF=est:aj44f09.s1 /CLONE=1393193 /UG=Hs.81412 lipin 1 AA813260 lipin 1 LPIN1 23175 NM_001261427 /// NM_001261428 /// NM_001261429 /// NM_145693 /// XM_006711869 /// XM_006711870 /// XM_006711871 /// XM_006711872 /// XM_006711873 /// XM_006711874 /// XM_006711875 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006642 // triglyceride mobilization // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0009062 // fatty acid catabolic process // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from sequence or structural similarity 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation 212273_x_at AI591100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI591100 /FEA=EST /DB_XREF=gi:4600148 /DB_XREF=est:tw91c03.x1 /CLONE=IMAGE:2267044 /UG=Hs.113368 neuroendocrine secretory protein 55 AI591100 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 212274_at AV705559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705559 /FEA=EST /DB_XREF=gi:10722858 /DB_XREF=est:AV705559 /CLONE=ADBAPE04 /UG=Hs.81412 lipin 1 AV705559 lipin 1 LPIN1 23175 NM_001261427 /// NM_001261428 /// NM_001261429 /// NM_145693 /// XM_006711869 /// XM_006711870 /// XM_006711871 /// XM_006711872 /// XM_006711873 /// XM_006711874 /// XM_006711875 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006642 // triglyceride mobilization // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0009062 // fatty acid catabolic process // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from sequence or structural similarity 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation 212275_s_at NM_006662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006662.1 /DEF=Homo sapiens Snf2-related CBP activator protein (SRCAP), mRNA. /FEA=CDS /GEN=SRCAP /PROD=Snf2-related CBP activator protein /DB_XREF=gi:5730066 /UG=Hs.87908 Snf2-related CBP activator protein /FL=gb:AF143946.1 gb:NM_006662.1 NM_006662 Snf2-related CREBBP activator protein SRCAP 10847 NM_006662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212276_at D80010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D80010.1 /DEF=Human mRNA for KIAA0188 gene, partial cds. /FEA=mRNA /GEN=KIAA0188 /DB_XREF=gi:1136435 /UG=Hs.81412 lipin 1 D80010 lipin 1 LPIN1 23175 NM_001261427 /// NM_001261428 /// NM_001261429 /// NM_145693 /// XM_006711869 /// XM_006711870 /// XM_006711871 /// XM_006711872 /// XM_006711873 /// XM_006711874 /// XM_006711875 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006642 // triglyceride mobilization // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0009062 // fatty acid catabolic process // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from sequence or structural similarity 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation 212277_at AB014547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014547.1 /DEF=Homo sapiens mRNA for KIAA0647 protein, partial cds. /FEA=mRNA /GEN=KIAA0647 /PROD=KIAA0647 protein /DB_XREF=gi:3327107 /UG=Hs.141727 myotubularin related protein 4 /FL=gb:NM_004687.1 gb:AF264717.1 AB014547 myotubularin related protein 4 MTMR4 9110 NM_004687 /// XM_005257784 /// XM_005257785 /// XM_005257786 /// XM_006722168 0006470 // protein dephosphorylation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212278_x_at BF588511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF588511 /FEA=EST /DB_XREF=gi:11680835 /DB_XREF=est:7i02d08.x1 /CLONE=IMAGE:3324303 /UG=Hs.180686 ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) /FL=gb:BC002582.1 gb:NM_000462.1 BF588511 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0035037 // sperm entry // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 212279_at BE779865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE779865 /FEA=EST /DB_XREF=gi:10201075 /DB_XREF=est:601465390F1 /CLONE=IMAGE:3868390 /UG=Hs.199695 hypothetical protein BE779865 transmembrane protein 97 TMEM97 27346 NM_014573 /// XM_005257965 0001558 // regulation of cell growth // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212280_x_at AA532726 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA532726 /FEA=EST /DB_XREF=gi:2278302 /DB_XREF=est:nj21e02.s1 /CLONE=IMAGE:993146 /UG=Hs.272586 KIAA0943 protein AA532726 autophagy related 4B, cysteine peptidase ATG4B 23192 NM_013325 /// NM_178326 /// XM_005246992 /// XM_005246993 /// XM_005246995 /// XM_005246996 /// XM_006712371 0000045 // autophagic vacuole assembly // inferred from genetic interaction /// 0000422 // mitochondrion degradation // not recorded /// 0006501 // C-terminal protein lipidation // not recorded /// 0006508 // proteolysis // inferred from direct assay /// 0006612 // protein targeting to membrane // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0051697 // protein delipidation // not recorded 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0004175 // endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 212281_s_at BF038366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF038366 /FEA=EST /DB_XREF=gi:10744142 /DB_XREF=est:601459338F1 /CLONE=IMAGE:3862808 /UG=Hs.199695 hypothetical protein BF038366 transmembrane protein 97 TMEM97 27346 NM_014573 /// XM_005257965 0001558 // regulation of cell growth // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212282_at BF038366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF038366 /FEA=EST /DB_XREF=gi:10744142 /DB_XREF=est:601459338F1 /CLONE=IMAGE:3862808 /UG=Hs.199695 hypothetical protein BF038366 transmembrane protein 97 TMEM97 27346 NM_014573 /// XM_005257965 0001558 // regulation of cell growth // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212283_at AI424797 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI424797 /FEA=EST /DB_XREF=gi:4270728 /DB_XREF=est:tg49b04.x1 /CLONE=IMAGE:2112079 /UG=Hs.273330 Homo sapiens, clone IMAGE:3506210, mRNA, partial cds AI424797 agrin AGRN 375790 NM_198576 /// XM_005244749 /// XM_006710633 /// XM_006710634 /// XM_006710635 /// XM_006710636 /// XM_006710637 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from direct assay /// 0043113 // receptor clustering // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045162 // clustering of voltage-gated sodium channels // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045887 // positive regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050808 // synapse organization // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from sequence or structural similarity /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0030548 // acetylcholine receptor regulator activity // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // traceable author statement /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity 212284_x_at BG498776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG498776 /FEA=EST /DB_XREF=gi:13460293 /DB_XREF=est:602544416F1 /CLONE=IMAGE:4666995 /UG=Hs.326456 hypothetical protein FLJ20030 BG498776 uncharacterized LOC101928826 /// tumor protein, translationally-controlled 1 LOC101928826 /// TPT1 7178 /// 101928826 NM_001286272 /// NM_001286273 /// NM_003295 /// XR_242670 /// XR_250536 /// XR_252641 0006816 // calcium ion transport // inferred by curator /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0009615 // response to virus // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000384 // negative regulation of ectoderm development // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005771 // multivesicular body // inferred from direct assay /// 0045298 // tubulin complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212285_s_at AW008051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW008051 /FEA=EST /DB_XREF=gi:5856829 /DB_XREF=est:wv48h10.x1 /CLONE=IMAGE:2532835 /UG=Hs.273330 Homo sapiens, clone IMAGE:3506210, mRNA, partial cds AW008051 agrin AGRN 375790 NM_198576 /// XM_005244749 /// XM_006710633 /// XM_006710634 /// XM_006710635 /// XM_006710636 /// XM_006710637 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from direct assay /// 0043113 // receptor clustering // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045162 // clustering of voltage-gated sodium channels // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045887 // positive regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050808 // synapse organization // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from sequence or structural similarity /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0030548 // acetylcholine receptor regulator activity // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // traceable author statement /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity 212286_at AW572909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW572909 /FEA=EST /DB_XREF=gi:7237642 /DB_XREF=est:hf17d03.x1 /CLONE=IMAGE:2932133 /UG=Hs.27973 KIAA0874 protein /FL=gb:AF317425.1 AW572909 ankyrin repeat domain 12 ANKRD12 23253 NM_001083625 /// NM_001204056 /// NM_015208 /// XM_005258092 /// XM_005258093 /// XM_005258094 /// XM_005258095 /// XM_005258096 /// XM_006722317 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212287_at BF382924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF382924 /FEA=EST /DB_XREF=gi:11364313 /DB_XREF=est:601816985F1 /CLONE=IMAGE:4050909 /UG=Hs.197803 KIAA0160 protein BF382924 SUZ12 polycomb repressive complex 2 subunit SUZ12 23512 NM_015355 /// XM_005257954 /// XM_006721794 /// XR_243773 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from mutant phenotype 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from mutant phenotype 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212288_at AB011126 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011126.1 /DEF=Homo sapiens mRNA for KIAA0554 protein, partial cds. /FEA=mRNA /GEN=KIAA0554 /PROD=KIAA0554 protein /DB_XREF=gi:3043631 /UG=Hs.301763 KIAA0554 protein AB011126 formin binding protein 1 FNBP1 23048 NM_015033 /// XM_005251815 /// XM_005251816 /// XM_005251817 /// XM_005251818 /// XM_005251819 /// XM_005251820 /// XM_005251821 /// XM_005251822 /// XM_005251823 /// XM_005251824 /// XM_005251825 /// XM_005251826 /// XM_005251827 /// XM_005251828 /// XM_005251829 /// XM_005251830 /// XM_005251831 /// XM_005251832 /// XM_005251833 /// XM_005251834 /// XM_006717016 /// XM_006717017 0006412 // translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 212289_at AB020681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020681.1 /DEF=Homo sapiens mRNA for KIAA0874 protein, partial cds. /FEA=mRNA /GEN=KIAA0874 /PROD=KIAA0874 protein /DB_XREF=gi:4240236 /UG=Hs.27973 KIAA0874 protein /FL=gb:AF317425.1 AB020681 ankyrin repeat domain 12 ANKRD12 23253 NM_001083625 /// NM_001204056 /// NM_015208 /// XM_005258092 /// XM_005258093 /// XM_005258094 /// XM_005258095 /// XM_005258096 /// XM_006722317 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212290_at AA527433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527433 /FEA=EST /DB_XREF=gi:2269502 /DB_XREF=est:ng41b03.s1 /CLONE=IMAGE:937325 /UG=Hs.14846 Homo sapiens mRNA; cDNA DKFZp564D016 (from clone DKFZp564D016) AA527433 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 SLC7A1 6541 NM_003045 /// XM_005266507 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015809 // arginine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation 212291_at AI393355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI393355 /FEA=EST /DB_XREF=gi:4222902 /DB_XREF=est:tg44d05.x1 /CLONE=IMAGE:2111625 /UG=Hs.12259 KIAA0630 protein AI393355 homeodomain interacting protein kinase 1 HIPK1 204851 NM_152696 /// NM_181358 /// NM_198268 /// NM_198269 /// XM_005270609 /// XM_005270610 /// XM_005270611 /// XM_005270612 /// XM_005270613 /// XM_006710443 0001654 // eye development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010803 // regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from electronic annotation /// 0072577 // endothelial cell apoptotic process // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 212292_at AW452623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW452623 /FEA=EST /DB_XREF=gi:6993399 /DB_XREF=est:UI-H-BI3-alu-d-09-0-UI.s1 /CLONE=IMAGE:3068608 /UG=Hs.14846 Homo sapiens mRNA; cDNA DKFZp564D016 (from clone DKFZp564D016) AW452623 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 SLC7A1 6541 NM_003045 /// XM_005266507 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015809 // arginine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation 212293_at BG111260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG111260 /FEA=EST /DB_XREF=gi:12604766 /DB_XREF=est:602281701F1 /CLONE=IMAGE:4369057 /UG=Hs.12259 KIAA0630 protein BG111260 homeodomain interacting protein kinase 1 HIPK1 204851 NM_152696 /// NM_181358 /// NM_198268 /// NM_198269 /// XM_005270609 /// XM_005270610 /// XM_005270611 /// XM_005270612 /// XM_005270613 /// XM_006710443 0001654 // eye development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010803 // regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from electronic annotation /// 0072577 // endothelial cell apoptotic process // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 212294_at BG111761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG111761 /FEA=EST /DB_XREF=gi:12605267 /DB_XREF=est:602285343F1 /CLONE=IMAGE:4372619 /UG=Hs.8107 Homo sapiens mRNA; cDNA DKFZp586B0918 (from clone DKFZp586B0918) BG111761 guanine nucleotide binding protein (G protein), gamma 12 GNG12 55970 NM_018841 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042301 // phosphate ion binding // inferred from electronic annotation 212295_s_at AA148507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA148507 /FEA=EST /DB_XREF=gi:1721551 /DB_XREF=est:zl06c05.s1 /CLONE=IMAGE:491528 /UG=Hs.14846 Homo sapiens mRNA; cDNA DKFZp564D016 (from clone DKFZp564D016) AA148507 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 SLC7A1 6541 NM_003045 /// XM_005266507 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015809 // arginine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation 212296_at NM_005805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005805.1 /DEF=Homo sapiens 26S proteasome-associated pad1 homolog (POH1), mRNA. /FEA=CDS /GEN=POH1 /PROD=26S proteasome-associated pad1 homolog /DB_XREF=gi:5031980 /UG=Hs.178761 26S proteasome-associated pad1 homolog /FL=gb:U86782.1 gb:NM_005805.1 NM_005805 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 PSMD14 10213 NM_005805 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008541 // proteasome regulatory particle, lid subcomplex // inferred from mutant phenotype /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061133 // endopeptidase activator activity // inferred from mutant phenotype /// 0070628 // proteasome binding // inferred from direct assay 212297_at BF218804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF218804 /FEA=EST /DB_XREF=gi:11112494 /DB_XREF=est:601882315F1 /CLONE=IMAGE:4094786 /UG=Hs.4934 H.sapiens polyA site DNA BF218804 ATPase type 13A3 ATP13A3 79572 NM_024524 /// XM_005269357 /// XM_005269358 /// XM_005269360 /// XM_006713742 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212298_at BE620457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE620457 /FEA=EST /DB_XREF=gi:9891395 /DB_XREF=est:601483690F1 /CLONE=IMAGE:3886055 /UG=Hs.69285 neuropilin 1 /FL=gb:AF018956.1 gb:AF016050.1 gb:NM_003873.1 BE620457 neuropilin 1 NRP1 8829 NM_001024628 /// NM_001024629 /// NM_001244972 /// NM_001244973 /// NM_003873 /// NR_045259 /// XM_006717521 /// XM_006717522 /// XM_006717523 /// XM_006717524 /// XM_006717525 /// XM_006717526 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021636 // trigeminal nerve morphogenesis // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from mutant phenotype /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0038190 // VEGF-activated neuropilin signaling pathway // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048841 // regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0060301 // positive regulation of cytokine activity // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from sequence or structural similarity /// 0060627 // regulation of vesicle-mediated transport // traceable author statement /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0060978 // angiogenesis involved in coronary vascular morphogenesis // inferred from sequence or structural similarity /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // non-traceable author statement /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 0090259 // regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0097102 // endothelial tip cell fate specification // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1901166 // neural crest cell migration involved in autonomic nervous system development // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity /// 1902336 // positive regulation of retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 1902946 // protein localization to early endosome // inferred from sequence or structural similarity /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005883 // neurofilament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // traceable author statement /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0015026 // coreceptor activity // traceable author statement /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212299_at AL117502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117502.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D0935 (from clone DKFZp434D0935). /FEA=mRNA /DB_XREF=gi:5912009 /UG=Hs.7200 Homo sapiens mRNA; cDNA DKFZp434D0935 (from clone DKFZp434D0935) AL117502 NIMA-related kinase 9 NEK9 91754 NM_033116 /// XM_005268208 /// XM_005268209 /// XM_006720303 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212300_at AL049795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049795 /DEF=Human DNA sequence from clone RP4-622L5 on chromosome 1p34.2-36.11. Contains the gene for importin alpha 7 (karyopherin), up to six novel genes and the 5 end of the EIF3S2 gene for eukaryotic translation initiation factor 3 beta. Contains ESTs, S... /FEA=mRNA_7 /DB_XREF=gi:6010175 /UG=Hs.83004 interleukin 14 AL049795 taxilin alpha TXLNA 200081 NM_175852 /// XM_005270594 /// XM_006710424 0006887 // exocytosis // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005125 // cytokine activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030372 // high molecular weight B cell growth factor receptor binding // non-traceable author statement 212301_at D87440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87440.1 /DEF=Human mRNA for KIAA0252 gene, partial cds. /FEA=mRNA /GEN=KIAA0252 /DB_XREF=gi:1665770 /UG=Hs.83419 KIAA0252 protein D87440 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) RTF1 23168 NM_015138 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016570 // histone modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212302_at AI192081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI192081 /FEA=EST /DB_XREF=gi:3743290 /DB_XREF=est:qc95c07.x1 /CLONE=IMAGE:1721964 /UG=Hs.83419 KIAA0252 protein AI192081 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) RTF1 23168 NM_015138 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016570 // histone modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212303_x_at BG026366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG026366 /FEA=EST /DB_XREF=gi:12413905 /DB_XREF=est:602291736F1 /CLONE=IMAGE:4386489 /UG=Hs.91142 KH-type splicing regulatory protein (FUSE binding protein 2) BG026366 KH-type splicing regulatory protein KHSRP 8570 NM_003685 /// XM_005259668 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212305_s_at AK025122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025122.1 /DEF=Homo sapiens cDNA: FLJ21469 fis, clone COL04876. /FEA=mRNA /DB_XREF=gi:10437575 /UG=Hs.241552 KIAA0268 protein AK025122 melanoma inhibitory activity family, member 3 MIA3 375056 NM_198551 /// XM_005273121 /// XM_005273122 /// XM_006711304 0002063 // chondrocyte development // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0015031 // protein transport // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212306_at AI741784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741784 /FEA=EST /DB_XREF=gi:5110072 /DB_XREF=est:wg22h09.x1 /CLONE=IMAGE:2365889 /UG=Hs.108614 KIAA0627 protein; Drosophila multiple asters (Mast)-like homolog 2 AI741784 cytoplasmic linker associated protein 2 CLASP2 23122 NM_001207044 /// NM_015097 /// XM_006713036 /// XM_006713037 /// XM_006713038 /// XM_006713039 /// XM_006713040 /// XM_006713041 /// XM_006713042 /// XM_006713043 /// XM_006713044 /// XM_006713045 /// XM_006713046 /// XM_006713047 /// XM_006713048 /// XM_006713049 /// XM_006713050 /// XM_006713051 /// XM_006713052 /// XM_006713053 /// XM_006713054 /// XM_006713055 /// XM_006713056 /// XM_006713057 /// XM_006713058 /// XM_006713059 /// XM_006713060 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0036065 // fucosylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // non-traceable author statement /// 0043515 // kinetochore binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 212307_s_at BF001665 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001665 /FEA=EST /DB_XREF=gi:10701940 /DB_XREF=est:7g91d11.x1 /CLONE=IMAGE:3313845 /UG=Hs.100293 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) BF001665 O-linked N-acetylglucosamine (GlcNAc) transferase OGT 8473 NM_003605 /// NM_181672 /// NM_181673 /// XM_005262308 /// XM_006724714 0006110 // regulation of glycolytic process // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from sequence or structural similarity 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070688 // MLL5-L complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay /// 0097363 // protein O-GlcNAc transferase activity // inferred from sequence or structural similarity 212308_at AL137636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137636.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F075 (from clone DKFZp434F075); partial cds. /FEA=mRNA /GEN=DKFZp434F075 /PROD=hypothetical protein /DB_XREF=gi:6808436 /UG=Hs.108614 KIAA0627 protein; Drosophila multiple asters (Mast)-like homolog 2 AL137636 cytoplasmic linker associated protein 2 CLASP2 23122 NM_001207044 /// NM_015097 /// XM_006713036 /// XM_006713037 /// XM_006713038 /// XM_006713039 /// XM_006713040 /// XM_006713041 /// XM_006713042 /// XM_006713043 /// XM_006713044 /// XM_006713045 /// XM_006713046 /// XM_006713047 /// XM_006713048 /// XM_006713049 /// XM_006713050 /// XM_006713051 /// XM_006713052 /// XM_006713053 /// XM_006713054 /// XM_006713055 /// XM_006713056 /// XM_006713057 /// XM_006713058 /// XM_006713059 /// XM_006713060 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0036065 // fucosylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // non-traceable author statement /// 0043515 // kinetochore binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 212309_at AV725315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV725315 /FEA=EST /DB_XREF=gi:10830580 /DB_XREF=est:AV725315 /CLONE=HTCCAG11 /UG=Hs.108614 KIAA0627 protein; Drosophila multiple asters (Mast)-like homolog 2 AV725315 cytoplasmic linker associated protein 2 CLASP2 23122 NM_001207044 /// NM_015097 /// XM_006713036 /// XM_006713037 /// XM_006713038 /// XM_006713039 /// XM_006713040 /// XM_006713041 /// XM_006713042 /// XM_006713043 /// XM_006713044 /// XM_006713045 /// XM_006713046 /// XM_006713047 /// XM_006713048 /// XM_006713049 /// XM_006713050 /// XM_006713051 /// XM_006713052 /// XM_006713053 /// XM_006713054 /// XM_006713055 /// XM_006713056 /// XM_006713057 /// XM_006713058 /// XM_006713059 /// XM_006713060 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0036065 // fucosylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008107 // galactoside 2-alpha-L-fucosyltransferase activity // non-traceable author statement /// 0043515 // kinetochore binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 212310_at D87742 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87742.1 /DEF=Human mRNA for KIAA0268 gene, partial cds. /FEA=mRNA /GEN=KIAA0268 /DB_XREF=gi:1665824 /UG=Hs.241552 KIAA0268 protein D87742 melanoma inhibitory activity family, member 3 MIA3 375056 NM_198551 /// XM_005273121 /// XM_005273122 /// XM_006711304 0002063 // chondrocyte development // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0015031 // protein transport // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212311_at AA522514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA522514 /FEA=EST /DB_XREF=gi:2263226 /DB_XREF=est:ni38c01.s1 /CLONE=IMAGE:979104 /UG=Hs.49500 KIAA0746 protein AA522514 sel-1 suppressor of lin-12-like 3 (C. elegans) SEL1L3 23231 NM_015187 /// XM_005248143 /// XM_006713956 /// XM_006713957 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212312_at AL117381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117381 /DEF=Human DNA sequence from clone RP5-857M17 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands. Contains the 3 part of the ID1 gene for inhibitor of DNA binding 1 (dominant negative helix-loop-helix protein), a gene for a novel protein simil... /FEA=mRNA_1 /DB_XREF=gi:11493211 /UG=Hs.305890 BCL2-like 1 AL117381 BCL2-like 1 BCL2L1 598 NM_001191 /// NM_138578 /// XM_005260481 /// XM_005260482 /// XM_005260483 /// XM_005260484 /// XM_005260485 /// XM_005260486 /// XM_005260487 /// XM_006723843 /// XM_006723844 /// XM_006723845 0000910 // cytokinesis // inferred from mutant phenotype /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0019050 // suppression by virus of host apoptotic process // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046898 // response to cycloheximide // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071839 // apoptotic process in bone marrow // inferred from electronic annotation /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred by curator /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // non-traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded /// 0051434 // BH3 domain binding // inferred from physical interaction 212313_at BC004344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004344.1 /DEF=Homo sapiens, clone IMAGE:3633354, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3633354) /DB_XREF=gi:13279286 /UG=Hs.5019 Homo sapiens, clone IMAGE:3633354, mRNA, partial cds BC004344 charged multivesicular body protein 7 CHMP7 91782 NM_152272 /// XM_005273687 /// XM_006716415 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0045324 // late endosome to vacuole transport // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement 0000815 // ESCRT III complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0008565 // protein transporter activity // inferred from mutant phenotype 212314_at AB018289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018289.1 /DEF=Homo sapiens mRNA for KIAA0746 protein, partial cds. /FEA=mRNA /GEN=KIAA0746 /PROD=KIAA0746 protein /DB_XREF=gi:3882212 /UG=Hs.49500 KIAA0746 protein AB018289 sel-1 suppressor of lin-12-like 3 (C. elegans) SEL1L3 23231 NM_015187 /// XM_005248143 /// XM_006713956 /// XM_006713957 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212315_s_at AA502912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA502912 /FEA=EST /DB_XREF=gi:2237879 /DB_XREF=est:ne42d10.s1 /CLONE=IMAGE:900019 /UG=Hs.56966 KIAA0906 protein AA502912 nucleoporin 210kDa NUP210 23225 NM_024923 /// XM_005264994 /// XR_245105 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212316_at AA502912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA502912 /FEA=EST /DB_XREF=gi:2237879 /DB_XREF=est:ne42d10.s1 /CLONE=IMAGE:900019 /UG=Hs.56966 KIAA0906 protein AA502912 nucleoporin 210kDa NUP210 23225 NM_024923 /// XM_005264994 /// XR_245105 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212317_at AK022910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022910.1 /DEF=Homo sapiens cDNA FLJ12848 fis, clone NT2RP2003391, highly similar to Homo sapiens mRNA for nuclear transport receptor. /FEA=mRNA /DB_XREF=gi:10434575 /UG=Hs.69235 transportin-SR /FL=gb:NM_012470.1 AK022910 transportin 3 TNPO3 23534 NM_001191028 /// NM_012470 /// NR_034053 /// XM_006715911 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035048 // splicing factor protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212318_at NM_012470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012470.1 /DEF=Homo sapiens transportin-SR (TRN-SR), mRNA. /FEA=CDS /GEN=TRN-SR /PROD=transportin-SR /DB_XREF=gi:6912733 /UG=Hs.69235 transportin-SR /FL=gb:NM_012470.1 NM_012470 transportin 3 TNPO3 23534 NM_001191028 /// NM_012470 /// NR_034053 /// XM_006715911 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035048 // splicing factor protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212319_at AB007857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007857.2 /DEF=Homo sapiens mRNA for KIAA0397 protein, partial cds. /FEA=mRNA /GEN=KIAA0397 /PROD=KIAA0397 protein /DB_XREF=gi:6634026 /UG=Hs.7416 KIAA0397 gene product AB007857 small G protein signaling modulator 2 SGSM2 9905 NM_001098509 /// NM_014853 /// XM_006721613 /// XM_006721614 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 212320_at BC001002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001002.1 /DEF=Homo sapiens, clone IMAGE:3447696, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3447696) /DB_XREF=gi:12654358 /UG=Hs.179661 tubulin, beta polypeptide BC001002 tubulin, beta class I TUBB 203068 NM_001293212 /// NM_001293213 /// NM_001293214 /// NM_001293215 /// NM_001293216 /// NM_178014 /// NR_120608 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0009987 // cellular process // inferred from direct assay /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay 212321_at AB033078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033078.1 /DEF=Homo sapiens mRNA for KIAA1252 protein, partial cds. /FEA=mRNA /GEN=KIAA1252 /PROD=KIAA1252 protein /DB_XREF=gi:6330873 /UG=Hs.186613 sphingosine-1-phosphate lyase 1 /FL=gb:AF144638.1 AB033078 sphingosine-1-phosphate lyase 1 SGPL1 8879 NM_003901 /// XM_005270263 /// XM_006718052 /// XM_006718053 0001553 // luteinization // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008117 // sphinganine-1-phosphate aldolase activity // inferred from direct assay /// 0008117 // sphinganine-1-phosphate aldolase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 212322_at BE999972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE999972 /FEA=EST /DB_XREF=gi:10700248 /DB_XREF=est:7h15b02.x1 /CLONE=IMAGE:3316011 /UG=Hs.186613 sphingosine-1-phosphate lyase 1 /FL=gb:AF144638.1 BE999972 sphingosine-1-phosphate lyase 1 SGPL1 8879 NM_003901 /// XM_005270263 /// XM_006718052 /// XM_006718053 0001553 // luteinization // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008117 // sphinganine-1-phosphate aldolase activity // inferred from direct assay /// 0008117 // sphinganine-1-phosphate aldolase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 212323_s_at AA524553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524553 /FEA=EST /DB_XREF=gi:2265481 /DB_XREF=est:ng45h12.s1 /CLONE=IMAGE:937799 /UG=Hs.194737 KIAA0453 protein AA524553 vacuolar protein sorting 13 homolog D (S. cerevisiae) VPS13D 55187 NM_015378 /// NM_018156 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 212324_s_at BF111962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF111962 /FEA=EST /DB_XREF=gi:10941741 /DB_XREF=est:7l39d05.x1 /CLONE=IMAGE:3523641 /UG=Hs.194737 KIAA0453 protein BF111962 vacuolar protein sorting 13 homolog D (S. cerevisiae) VPS13D 55187 NM_015378 /// NM_018156 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 212325_at AK027231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027231.1 /DEF=Homo sapiens cDNA: FLJ23578 fis, clone LNG12709. /FEA=mRNA /DB_XREF=gi:10440313 /UG=Hs.202949 KIAA1102 protein AK027231 LIM and calponin homology domains 1 LIMCH1 22998 NM_001112717 /// NM_001112718 /// NM_001112719 /// NM_001112720 /// NM_001289122 /// NM_001289124 /// NM_014988 /// XM_005248057 /// XM_005248058 /// XM_005248059 /// XM_005248060 /// XM_005248061 /// XM_005248062 /// XM_005248063 /// XM_005248064 /// XM_005248065 /// XM_005248066 /// XM_005248067 /// XM_005248068 /// XM_005248069 /// XM_005248070 /// XM_005248071 /// XM_005248072 /// XM_005248073 /// XM_005248074 /// XM_005248075 /// XM_006713996 /// XM_006713997 /// XM_006713998 0031032 // actomyosin structure organization // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212326_at AB007922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007922.2 /DEF=Homo sapiens mRNA for KIAA0453 protein, partial cds. /FEA=mRNA /GEN=KIAA0453 /PROD=KIAA0453 protein /DB_XREF=gi:6634036 /UG=Hs.194737 KIAA0453 protein AB007922 vacuolar protein sorting 13 homolog D (S. cerevisiae) VPS13D 55187 NM_015378 /// NM_018156 0070062 // extracellular vesicular exosome // inferred from direct assay 212327_at AK026815 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026815.1 /DEF=Homo sapiens cDNA: FLJ23162 fis, clone LNG09734. /FEA=mRNA /DB_XREF=gi:10439759 /UG=Hs.202949 KIAA1102 protein AK026815 LIM and calponin homology domains 1 LIMCH1 22998 NM_001112717 /// NM_001112718 /// NM_001112719 /// NM_001112720 /// NM_001289122 /// NM_001289124 /// NM_014988 /// XM_005248057 /// XM_005248058 /// XM_005248059 /// XM_005248060 /// XM_005248061 /// XM_005248062 /// XM_005248063 /// XM_005248064 /// XM_005248065 /// XM_005248066 /// XM_005248067 /// XM_005248068 /// XM_005248069 /// XM_005248070 /// XM_005248071 /// XM_005248072 /// XM_005248073 /// XM_005248074 /// XM_005248075 /// XM_006713996 /// XM_006713997 /// XM_006713998 0031032 // actomyosin structure organization // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212328_at AB029025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029025.1 /DEF=Homo sapiens mRNA for KIAA1102 protein, partial cds. /FEA=mRNA /GEN=KIAA1102 /PROD=KIAA1102 protein /DB_XREF=gi:5689540 /UG=Hs.202949 KIAA1102 protein AB029025 LIM and calponin homology domains 1 LIMCH1 22998 NM_001112717 /// NM_001112718 /// NM_001112719 /// NM_001112720 /// NM_001289122 /// NM_001289124 /// NM_014988 /// XM_005248057 /// XM_005248058 /// XM_005248059 /// XM_005248060 /// XM_005248061 /// XM_005248062 /// XM_005248063 /// XM_005248064 /// XM_005248065 /// XM_005248066 /// XM_005248067 /// XM_005248068 /// XM_005248069 /// XM_005248070 /// XM_005248071 /// XM_005248072 /// XM_005248073 /// XM_005248074 /// XM_005248075 /// XM_006713996 /// XM_006713997 /// XM_006713998 0031032 // actomyosin structure organization // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212329_at D83782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D83782.1 /DEF=Human mRNA for KIAA0199 gene, partial cds. /FEA=mRNA /GEN=KIAA0199 /DB_XREF=gi:1228046 /UG=Hs.78442 SREBP CLEAVAGE-ACTIVATING PROTEIN D83782 SREBF chaperone SCAP 22937 NM_012235 /// XM_005264967 /// XM_005264968 /// XM_005264969 /// XM_005264970 /// XM_005264971 /// XM_005264972 /// XM_006713034 0001666 // response to hypoxia // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from mutant phenotype /// 0042304 // regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // non-traceable author statement /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // non-traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 212330_at R60866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R60866 /FEA=EST /DB_XREF=gi:831561 /DB_XREF=est:yh08a11.s1 /CLONE=IMAGE:42383 /UG=Hs.79353 hypothetical protein FLJ13576 R60866 transcription factor Dp-1 TFDP1 7027 NM_007111 /// NR_026580 /// XM_005268326 /// XM_005268327 /// XM_005268328 /// XM_005268330 /// XM_005268331 /// XM_006719977 /// XM_006719978 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 212331_at X76061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X76061.1 /DEF=H.sapiens p130 mRNA for 130K protein. /FEA=mRNA /GEN=p130 /PROD=130K protein /DB_XREF=gi:416030 /UG=Hs.79362 retinoblastoma-like 2 (p130) /FL=gb:NM_005611.1 X76061 retinoblastoma-like 2 RBL2 5934 NM_005611 /// XM_005256083 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212332_at BF110947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110947 /FEA=EST /DB_XREF=gi:10940637 /DB_XREF=est:7n30f02.x1 /CLONE=IMAGE:3566330 /UG=Hs.79362 retinoblastoma-like 2 (p130) /FL=gb:NM_005611.1 BF110947 retinoblastoma-like 2 RBL2 5934 NM_005611 /// XM_005256083 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212333_at AL049943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049943.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F0522 (from clone DKFZp564F0522). /FEA=mRNA /GEN=DKFZp564F0522 /PROD=hypothetical protein /DB_XREF=gi:4884187 /UG=Hs.23060 DKFZP564F0522 protein AL049943 family with sequence similarity 98, member A FAM98A 25940 NM_015475 0044822 // poly(A) RNA binding // inferred from direct assay 212334_at BE880245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE880245 /FEA=EST /DB_XREF=gi:10329021 /DB_XREF=est:601490612F1 /CLONE=IMAGE:3893018 /UG=Hs.164036 Homo sapiens AKAP350C mRNA sequence, alternatively spliced BE880245 glucosamine (N-acetyl)-6-sulfatase GNS 2799 NM_002076 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212335_at AW167793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW167793 /FEA=EST /DB_XREF=gi:6399401 /DB_XREF=est:xg56d07.x1 /CLONE=IMAGE:2632333 /UG=Hs.164036 Homo sapiens AKAP350C mRNA sequence, alternatively spliced AW167793 glucosamine (N-acetyl)-6-sulfatase GNS 2799 NM_002076 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212336_at AA912711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA912711 /FEA=EST /DB_XREF=gi:3052103 /DB_XREF=est:ol30f08.s1 /CLONE=IMAGE:1524999 /UG=Hs.26395 erythrocyte membrane protein band 4.1-like 1 AA912711 erythrocyte membrane protein band 4.1-like 1 EPB41L1 2036 NM_001258329 /// NM_001258330 /// NM_001258331 /// NM_012156 /// NM_177996 /// XM_005260319 /// XM_005260320 /// XM_005260321 /// XM_005260322 /// XM_005260323 /// XM_005260324 /// XM_005260325 /// XM_006723735 /// XM_006723736 /// XM_006723737 /// XM_006723738 /// XM_006723739 /// XM_006723740 /// XM_006723741 0007268 // synaptic transmission // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 212337_at AI687738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI687738 /FEA=EST /DB_XREF=gi:4899032 /DB_XREF=est:tp93g08.x1 /CLONE=IMAGE:2206910 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) AI687738 taurine up-regulated 1 (non-protein coding) TUG1 55000 NR_002323 /// NR_110492 /// NR_110493 212338_at AA621962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA621962 /FEA=EST /DB_XREF=gi:2525838 /DB_XREF=est:nq24b02.s1 /CLONE=IMAGE:1144779 /UG=Hs.39871 KIAA0727 protein AA621962 myosin ID MYO1D 4642 NM_015194 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0061502 // early endosome to recycling endosome transport // inferred from sequence or structural similarity 0005768 // endosome // inferred from sequence or structural similarity /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000146 // microfilament motor activity // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation 212339_at AL121895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121895 /DEF=Human DNA sequence from clone RP11-234K24 on chromosome 20 Contains EPB41L1 gene encoding the erythrocyte membrane protein band 4.1-like protein (KIAA0338), a novel gene (CGI-23, DKFZP564N1363), a CpG island, ESTs, STSs and GSSs /FEA=mRNA_1 /DB_XREF=gi:9864397 /UG=Hs.26395 erythrocyte membrane protein band 4.1-like 1 AL121895 erythrocyte membrane protein band 4.1-like 1 EPB41L1 2036 NM_001258329 /// NM_001258330 /// NM_001258331 /// NM_012156 /// NM_177996 /// XM_005260319 /// XM_005260320 /// XM_005260321 /// XM_005260322 /// XM_005260323 /// XM_005260324 /// XM_005260325 /// XM_006723735 /// XM_006723736 /// XM_006723737 /// XM_006723738 /// XM_006723739 /// XM_006723740 /// XM_006723741 0007268 // synaptic transmission // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 212340_at BE673723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE673723 /FEA=EST /DB_XREF=gi:10034264 /DB_XREF=est:7d79h10.x1 /CLONE=IMAGE:3279235 /UG=Hs.82719 Homo sapiens mRNA; cDNA DKFZp586F1822 (from clone DKFZp586F1822) BE673723 Yip1 domain family, member 6 YIPF6 286451 NM_001195214 /// NM_173834 /// XR_430520 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 212341_at AA195936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA195936 /FEA=EST /DB_XREF=gi:1791527 /DB_XREF=est:zp99d04.s1 /CLONE=IMAGE:628327 /UG=Hs.82719 Homo sapiens mRNA; cDNA DKFZp586F1822 (from clone DKFZp586F1822) AA195936 Yip1 domain family, member 6 YIPF6 286451 NM_001195214 /// NM_173834 /// XR_430520 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 212342_at BG500611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG500611 /FEA=EST /DB_XREF=gi:13462128 /DB_XREF=est:602546082F1 /CLONE=IMAGE:4668261 /UG=Hs.82719 Homo sapiens mRNA; cDNA DKFZp586F1822 (from clone DKFZp586F1822) BG500611 Yip1 domain family, member 6 YIPF6 286451 NM_001195214 /// NM_173834 /// XR_430520 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 212343_at AL117461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117461.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1822 (from clone DKFZp586F1822). /FEA=mRNA /DB_XREF=gi:5911922 /UG=Hs.82719 Homo sapiens mRNA; cDNA DKFZp586F1822 (from clone DKFZp586F1822) AL117461 Yip1 domain family, member 6 YIPF6 286451 NM_001195214 /// NM_173834 /// XR_430520 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 212344_at AW043713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW043713 /FEA=EST /DB_XREF=gi:5904242 /DB_XREF=est:wy80e01.x1 /CLONE=IMAGE:2554872 /UG=Hs.70823 KIAA1077 protein AW043713 sulfatase 1 SULF1 23213 NM_001128204 /// NM_001128205 /// NM_001128206 /// NM_015170 /// XM_006716438 /// XM_006716439 /// XM_006716440 /// XM_006716441 /// XM_006716442 0001822 // kidney development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002063 // chondrocyte development // inferred from sequence or structural similarity /// 0003094 // glomerular filtration // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0014846 // esophagus smooth muscle contraction // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060384 // innervation // inferred from sequence or structural similarity /// 0060686 // negative regulation of prostatic bud formation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // inferred from direct assay /// 0004065 // arylsulfatase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from direct assay /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from mutant phenotype /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212345_s_at BE675139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675139 /FEA=EST /DB_XREF=gi:10035680 /DB_XREF=est:7f03b12.x1 /CLONE=IMAGE:3293567 /UG=Hs.13659 hypothetical protein DKFZp586F2423 BE675139 cAMP responsive element binding protein 3-like 2 CREB3L2 64764 NM_001253775 /// NM_194071 /// XM_005250541 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from expression pattern /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051216 // cartilage development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0035497 // cAMP response element binding // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 212346_s_at AK026392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026392.1 /DEF=Homo sapiens cDNA: FLJ22739 fis, clone HUV00686. /FEA=mRNA /DB_XREF=gi:10439242 /UG=Hs.102402 Mad4 homolog AK026392 microRNA 4800 /// MAX dimerization protein 4 MIR4800 /// MXD4 10608 /// 100616358 NM_006454 /// NR_039964 /// XR_427467 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212347_x_at AA831438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA831438 /FEA=EST /DB_XREF=gi:2904537 /DB_XREF=est:oc74e08.s1 /CLONE=IMAGE:1355462 /UG=Hs.102402 Mad4 homolog AA831438 microRNA 4800 /// MAX dimerization protein 4 MIR4800 /// MXD4 10608 /// 100616358 NM_006454 /// NR_039964 /// XR_427467 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212348_s_at AB011173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011173.1 /DEF=Homo sapiens mRNA for KIAA0601 protein, partial cds. /FEA=mRNA /GEN=KIAA0601 /PROD=KIAA0601 protein /DB_XREF=gi:3043725 /UG=Hs.174174 KIAA0601 protein AB011173 lysine (K)-specific demethylase 1A KDM1A 23028 NM_001009999 /// NM_015013 /// XM_005245786 /// XM_006710472 /// XM_006710473 /// XM_006710474 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006482 // protein demethylation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010725 // regulation of primitive erythrocyte differentiation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred by curator /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046886 // positive regulation of hormone biosynthetic process // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation /// 2000648 // positive regulation of stem cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0032451 // demethylase activity // inferred from mutant phenotype /// 0032452 // histone demethylase activity // inferred from direct assay /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0043426 // MRF binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay 212349_at AL045513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL045513 /FEA=EST /DB_XREF=gi:5433649 /DB_XREF=est:DKFZp434J015_r1 /CLONE=DKFZp434J015 /UG=Hs.178292 KIAA0180 protein AL045513 protein O-fucosyltransferase 1 POFUT1 23509 NM_015352 /// NM_172236 /// XR_430297 0001525 // angiogenesis // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0036066 // protein O-linked fucosylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046922 // peptide-O-fucosyltransferase activity // inferred from direct assay /// 0046922 // peptide-O-fucosyltransferase activity // traceable author statement 212350_at AB029031 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029031.1 /DEF=Homo sapiens mRNA for KIAA1108 protein, partial cds. /FEA=mRNA /GEN=KIAA1108 /PROD=KIAA1108 protein /DB_XREF=gi:5689552 /UG=Hs.278586 KIAA1108 protein AB029031 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 TBC1D1 23216 NM_001253912 /// NM_001253913 /// NM_001253914 /// NM_001253915 /// NM_015173 /// XM_005262646 /// XM_005262647 /// XM_005262648 /// XM_005262649 /// XM_005262651 /// XM_006713999 /// XM_006714000 /// XM_006714001 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212351_at U23028 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U23028.1 /DEF=Human eukaryotic initiation factor 2B-epsilon mRNA, partial cds. /FEA=mRNA /PROD=eIF-2Bepsilon /DB_XREF=gi:806853 /UG=Hs.2437 eukaryotic translation initiation factor 2B, subunit 5 (epsilon, 82kD) U23028 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa EIF2B5 8893 NM_003907 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0009408 // response to heat // inferred from mutant phenotype /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014002 // astrocyte development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0032057 // negative regulation of translational initiation in response to stress // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from direct assay /// 0042552 // myelination // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045948 // positive regulation of translational initiation // inferred from sequence or structural similarity /// 0048708 // astrocyte differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity 212352_s_at BE780075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE780075 /FEA=EST /DB_XREF=gi:10201273 /DB_XREF=est:601469954F1 /CLONE=IMAGE:3873157 /UG=Hs.74137 transmembrane trafficking protein BE780075 transmembrane emp24-like trafficking protein 10 (yeast) TMED10 10972 NM_006827 0001101 // response to acid // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from sequence or structural similarity /// 0007030 // Golgi organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034205 // beta-amyloid formation // inferred from mutant phenotype /// 0035459 // cargo loading into vesicle // traceable author statement /// 0035964 // COPI-coated vesicle budding // inferred from direct assay /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0048199 // vesicle targeting, to, from or within Golgi // inferred from sequence or structural similarity /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070765 // gamma-secretase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 212353_at AI479175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI479175 /FEA=EST /DB_XREF=gi:4372343 /DB_XREF=est:tm55c05.x1 /CLONE=IMAGE:2162024 /UG=Hs.70823 KIAA1077 protein AI479175 sulfatase 1 SULF1 23213 NM_001128204 /// NM_001128205 /// NM_001128206 /// NM_015170 /// XM_006716438 /// XM_006716439 /// XM_006716440 /// XM_006716441 /// XM_006716442 0001822 // kidney development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002063 // chondrocyte development // inferred from sequence or structural similarity /// 0003094 // glomerular filtration // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0014846 // esophagus smooth muscle contraction // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060384 // innervation // inferred from sequence or structural similarity /// 0060686 // negative regulation of prostatic bud formation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // inferred from direct assay /// 0004065 // arylsulfatase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from direct assay /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from mutant phenotype /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212354_at BE500977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE500977 /FEA=EST /DB_XREF=gi:9703385 /DB_XREF=est:7a33h02.x1 /CLONE=IMAGE:3220563 /UG=Hs.70823 KIAA1077 protein BE500977 sulfatase 1 SULF1 23213 NM_001128204 /// NM_001128205 /// NM_001128206 /// NM_015170 /// XM_006716438 /// XM_006716439 /// XM_006716440 /// XM_006716441 /// XM_006716442 0001822 // kidney development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002063 // chondrocyte development // inferred from sequence or structural similarity /// 0003094 // glomerular filtration // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0014846 // esophagus smooth muscle contraction // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // inferred from direct assay /// 0030201 // heparan sulfate proteoglycan metabolic process // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060384 // innervation // inferred from sequence or structural similarity /// 0060686 // negative regulation of prostatic bud formation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // inferred from direct assay /// 0004065 // arylsulfatase activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from direct assay /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from mutant phenotype /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212355_at AI075450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI075450 /FEA=EST /DB_XREF=gi:3399805 /DB_XREF=est:oz82g10.x1 /CLONE=IMAGE:1681890 /UG=Hs.7911 KIAA0323 protein AI075450 KH and NYN domain containing KHNYN 23351 NM_001290256 /// NM_001290257 /// NM_015299 /// XM_005267473 /// XM_005267474 /// XM_005267476 0003723 // RNA binding // inferred from electronic annotation 212356_at AB002321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002321.1 /DEF=Human mRNA for KIAA0323 gene, partial cds. /FEA=mRNA /GEN=KIAA0323 /DB_XREF=gi:2224586 /UG=Hs.7911 KIAA0323 protein AB002321 KH and NYN domain containing KHNYN 23351 NM_001290256 /// NM_001290257 /// NM_015299 /// XM_005267473 /// XM_005267474 /// XM_005267476 0003723 // RNA binding // inferred from electronic annotation 212357_at AI096888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI096888 /FEA=EST /DB_XREF=gi:3446470 /DB_XREF=est:qb58f08.x1 /CLONE=IMAGE:1704327 /UG=Hs.75400 KIAA0280 protein AI096888 family with sequence similarity 168, member A FAM168A 23201 NM_001286050 /// NM_001286051 /// NM_015159 /// XM_005273852 /// XM_006718482 212358_at AL117468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117468.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N1922 (from clone DKFZp586N1922); partial cds. /FEA=mRNA /GEN=DKFZp586N1922 /PROD=hypothetical protein /DB_XREF=gi:5911934 /UG=Hs.7357 DKFZP586N1922 protein AL117468 CAP-GLY domain containing linker protein 3 CLIP3 25999 NM_001199570 /// NM_015526 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0010828 // positive regulation of glucose transport // inferred from sequence or structural similarity /// 0018230 // peptidyl-L-cysteine S-palmitoylation // inferred from mutant phenotype /// 0031115 // negative regulation of microtubule polymerization // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0044091 // membrane biogenesis // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0072321 // chaperone-mediated protein transport // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from mutant phenotype /// 0045121 // membrane raft // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0035594 // ganglioside binding // inferred from direct assay 212359_s_at W89120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W89120 /FEA=EST /DB_XREF=gi:1404482 /DB_XREF=est:zh69b03.s1 /CLONE=IMAGE:417293 /UG=Hs.65135 KIAA0913 protein W89120 zinc finger, SWIM-type containing 8 ZSWIM8 23053 NM_001242487 /// NM_001242488 /// NM_015037 /// XM_005269648 /// XM_005269649 /// XM_005269651 /// XM_005269652 /// XM_005269653 /// XM_005269655 /// XM_006717725 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212360_at AI916249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI916249 /FEA=EST /DB_XREF=gi:5636104 /DB_XREF=est:wg99c01.x1 /CLONE=IMAGE:2379360 /UG=Hs.82927 adenosine monophosphate deaminase 2 (isoform L) /FL=gb:NM_004037.2 AI916249 adenosine monophosphate deaminase 2 AMPD2 271 NM_001257360 /// NM_001257361 /// NM_004037 /// NM_139156 /// NM_203404 /// XM_005270752 /// XM_006710576 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006163 // purine nucleotide metabolic process // non-traceable author statement /// 0006188 // IMP biosynthetic process // inferred from genetic interaction /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0032264 // IMP salvage // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0052652 // cyclic purine nucleotide metabolic process // inferred from mutant phenotype /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0097009 // energy homeostasis // inferred from genetic interaction 0005829 // cytosol // traceable author statement 0003876 // AMP deaminase activity // inferred from genetic interaction /// 0003876 // AMP deaminase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212361_s_at AW190070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190070 /FEA=EST /DB_XREF=gi:6464550 /DB_XREF=est:xl11f11.x1 /CLONE=IMAGE:2675949 /UG=Hs.1526 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 AW190070 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ATP2A2 488 NM_001135765 /// NM_001681 /// NM_170665 /// XM_005253888 /// XR_243009 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006984 // ER-nucleus signaling pathway // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010460 // positive regulation of heart rate // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0086036 // regulation of cardiac muscle cell membrane potential // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0086039 // calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential // traceable author statement 212362_at AA805753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA805753 /FEA=EST /DB_XREF=gi:2874503 /DB_XREF=est:ns43e04.s1 /CLONE=IMAGE:1186398 /UG=Hs.1526 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 AA805753 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ATP2A2 488 NM_001135765 /// NM_001681 /// NM_170665 /// XM_005253888 /// XR_243009 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006984 // ER-nucleus signaling pathway // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010460 // positive regulation of heart rate // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0086036 // regulation of cardiac muscle cell membrane potential // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0086039 // calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential // traceable author statement 212363_x_at AU145192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145192 /FEA=EST /DB_XREF=gi:11006713 /DB_XREF=est:AU145192 /CLONE=HEMBA1004153 /UG=Hs.14376 actin, gamma 1 AU145192 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 212364_at BF432550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432550 /FEA=EST /DB_XREF=gi:11444700 /DB_XREF=est:nac56e10.x1 /CLONE=IMAGE:3406555 /UG=Hs.121576 Homo sapiens cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 Homo sapiens incomplete cDNA for a mutated allele BF432550 myosin IB MYO1B 4430 NM_001130158 /// NM_001161819 /// NM_012223 /// XM_005246569 /// XM_005246572 /// XM_005246575 /// XM_005246577 /// XM_006712536 /// XM_006712537 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005769 // early endosome // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005903 // brush border // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from sequence or structural similarity 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000146 // microfilament motor activity // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from mutant phenotype 212365_at BF215996 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF215996 /FEA=EST /DB_XREF=gi:11109582 /DB_XREF=est:601881549F1 /CLONE=IMAGE:4093740 /UG=Hs.121576 Homo sapiens cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 Homo sapiens incomplete cDNA for a mutated allele BF215996 myosin IB MYO1B 4430 NM_001130158 /// NM_001161819 /// NM_012223 /// XM_005246569 /// XM_005246572 /// XM_005246575 /// XM_005246577 /// XM_006712536 /// XM_006712537 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005769 // early endosome // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005903 // brush border // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from sequence or structural similarity 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000146 // microfilament motor activity // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from mutant phenotype 212366_at BF223237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223237 /FEA=EST /DB_XREF=gi:11130414 /DB_XREF=est:7q30h09.x1 /CLONE=IMAGE:3700073 /UG=Hs.173081 KIAA0530 protein BF223237 zinc finger protein 292 ZNF292 23036 NM_015021 /// XM_005248697 /// XM_005248698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212367_at AI799061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799061 /FEA=EST /DB_XREF=gi:5364533 /DB_XREF=est:we98a10.x1 /CLONE=IMAGE:2349114 /UG=Hs.6048 FEM-1 (C.elegans) homolog b /FL=gb:AF178632.1 gb:NM_015322.1 gb:AF204883.1 AI799061 fem-1 homolog b (C. elegans) FEM1B 10116 NM_015322 /// XM_006720370 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005123 // death receptor binding // inferred from mutant phenotype /// 0005123 // death receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212368_at AA972711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA972711 /FEA=EST /DB_XREF=gi:3147891 /DB_XREF=est:op90e07.s1 /CLONE=IMAGE:1584132 /UG=Hs.173081 KIAA0530 protein AA972711 zinc finger protein 292 ZNF292 23036 NM_015021 /// XM_005248697 /// XM_005248698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212369_at AI264312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI264312 /FEA=EST /DB_XREF=gi:3872515 /DB_XREF=est:qi09a10.x1 /CLONE=IMAGE:1855962 /UG=Hs.103315 trinucleotide repeat containing 1 AI264312 zinc finger protein 384 ZNF384 171017 NM_001039916 /// NM_001039917 /// NM_001039918 /// NM_001039919 /// NM_001039920 /// NM_001135734 /// NM_133476 /// XM_006718963 /// XM_006718964 /// XM_006718965 /// XM_006718966 /// XM_006718967 /// XM_006718968 /// XM_006718969 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212370_x_at AL080183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080183.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O171 (from clone DKFZp434O171); partial cds. /FEA=mRNA /GEN=DKFZp434O171 /PROD=hypothetical protein /DB_XREF=gi:5262659 /UG=Hs.13273 KIAA0592 protein AL080183 family with sequence similarity 21, member A /// family with sequence similarity 21, member C /// uncharacterized LOC101930591 FAM21A /// FAM21C /// LOC101930591 253725 /// 387680 /// 101930591 NM_001005751 /// NM_001169106 /// NM_001169107 /// NM_001291398 /// NM_015262 /// NM_018232 /// XM_005269805 /// XM_005269806 /// XM_005269807 /// XM_005269808 /// XM_005269810 /// XM_006717831 /// XM_006717832 /// XR_247516 0006810 // transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay /// 0071203 // WASH complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 212371_at AL049397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049397.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C1019 (from clone DKFZp586C1019). /FEA=mRNA /DB_XREF=gi:4500188 /UG=Hs.12314 Homo sapiens mRNA; cDNA DKFZp586C1019 (from clone DKFZp586C1019) AL049397 desumoylating isopeptidase 2 DESI2 51029 NM_016076 /// XM_005273154 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212372_at AK026977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026977.1 /DEF=Homo sapiens cDNA: FLJ23324 fis, clone HEP12482, highly similar to HUMMYOHCB Human nonmuscle myosin heavy chain-B (MYH10) mRNA. /FEA=mRNA /DB_XREF=gi:10439970 /UG=Hs.296842 Homo sapiens, clone IMAGE:3357927, mRNA, partial cds AK026977 myosin, heavy chain 10, non-muscle MYH10 4628 NM_001256012 /// NM_001256095 /// NM_005964 /// XM_005256651 /// XM_005256652 /// XM_005256653 0000281 // mitotic cytokinesis // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001778 // plasma membrane repair // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006887 // exocytosis // inferred from electronic annotation /// 0006930 // substrate-dependent cell migration, cell extension // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0021592 // fourth ventricle development // inferred from electronic annotation /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0021678 // third ventricle development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0030239 // myofibril assembly // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016459 // myosin complex // non-traceable author statement /// 0016460 // myosin II complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0042641 // actomyosin // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // non-traceable author statement /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from mutant phenotype /// 0043531 // ADP binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from mutant phenotype 212373_at AW139179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139179 /FEA=EST /DB_XREF=gi:6143497 /DB_XREF=est:UI-H-BI1-aet-f-06-0-UI.s1 /CLONE=IMAGE:2720411 /UG=Hs.6048 FEM-1 (C.elegans) homolog b /FL=gb:AF178632.1 gb:NM_015322.1 gb:AF204883.1 AW139179 fem-1 homolog b (C. elegans) FEM1B 10116 NM_015322 /// XM_006720370 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005123 // death receptor binding // inferred from mutant phenotype /// 0005123 // death receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212374_at NM_015322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_015322.1 /DEF=Homo sapiens FEM-1 (C.elegans) homolog b (FEM1B), mRNA. /FEA=CDS /GEN=FEM1B /PROD=FEM-1-like death receptor binding protein /DB_XREF=gi:7657264 /UG=Hs.6048 FEM-1 (C.elegans) homolog b /FL=gb:AF178632.1 gb:NM_015322.1 gb:AF204883.1 NM_015322 fem-1 homolog b (C. elegans) FEM1B 10116 NM_015322 /// XM_006720370 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060743 // epithelial cell maturation involved in prostate gland development // inferred from electronic annotation /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005123 // death receptor binding // inferred from mutant phenotype /// 0005123 // death receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212375_at AL563727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL563727 /FEA=EST /DB_XREF=gi:12913403 /DB_XREF=est:AL563727 /CLONE=CS0DD007YL16 (3 prime) /UG=Hs.306094 trinucleotide repeat containing 12 AL563727 E1A binding protein p400 EP400 57634 NM_015409 0006325 // chromatin organization // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212376_s_at BE880591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE880591 /FEA=EST /DB_XREF=gi:10329367 /DB_XREF=est:601490987F1 /CLONE=IMAGE:3893204 /UG=Hs.306094 trinucleotide repeat containing 12 BE880591 E1A binding protein p400 EP400 57634 NM_015409 0006325 // chromatin organization // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212377_s_at AU158495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158495 /FEA=EST /DB_XREF=gi:11020016 /DB_XREF=est:AU158495 /CLONE=PLACE3000066 /UG=Hs.8121 Notch (Drosophila) homolog 2 AU158495 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 212378_at NM_000819 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000819.1 /DEF=Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), mRNA. /FEA=CDS /GEN=GART /PROD=phosphoribosylglycinamide formyltransferase,phosphoribosylglycinamide synthetase,phosphoribosylaminoimidazole synthetase /DB_XREF=gi:4503914 /UG=Hs.82285 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase /FL=gb:NM_000819.1 NM_000819 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART 2618 NM_000819 /// NM_001136005 /// NM_001136006 /// NM_175085 /// XM_005260941 /// XM_006723988 /// XM_006723989 /// XM_006723990 0003360 // brainstem development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004637 // phosphoribosylamine-glycine ligase activity // inferred from electronic annotation /// 0004641 // phosphoribosylformylglycinamidine cyclo-ligase activity // inferred from electronic annotation /// 0004644 // phosphoribosylglycinamide formyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212379_at BE966876 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966876 /FEA=EST /DB_XREF=gi:11772747 /DB_XREF=est:601660886R1 /CLONE=IMAGE:3915813 /UG=Hs.82285 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase /FL=gb:NM_000819.1 BE966876 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART 2618 NM_000819 /// NM_001136005 /// NM_001136006 /// NM_175085 /// XM_005260941 /// XM_006723988 /// XM_006723989 /// XM_006723990 0003360 // brainstem development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004637 // phosphoribosylamine-glycine ligase activity // inferred from electronic annotation /// 0004641 // phosphoribosylformylglycinamidine cyclo-ligase activity // inferred from electronic annotation /// 0004644 // phosphoribosylglycinamide formyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212380_at D43949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D43949.1 /DEF=Human mRNA for KIAA0082 gene, partial cds. /FEA=mRNA /GEN=KIAA0082 /DB_XREF=gi:603952 /UG=Hs.154045 KIAA0082 protein D43949 cap methyltransferase 1 CMTR1 23070 NM_015050 /// XM_005248955 /// XM_006715028 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0080009 // mRNA methylation // inferred from direct assay /// 0097309 // cap1 mRNA methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004483 // mRNA (nucleoside-2'-O-)-methyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 212381_at BF444943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF444943 /FEA=EST /DB_XREF=gi:11510081 /DB_XREF=est:nad19e01.x1 /CLONE=IMAGE:3365857 /UG=Hs.7243 ubiquitin specific protease 24 BF444943 ubiquitin specific peptidase 24 USP24 23358 NM_015306 /// XM_005270689 /// XM_005270690 /// XM_006710511 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 212382_at BF433429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF433429 /FEA=EST /DB_XREF=gi:11445592 /DB_XREF=est:7q53a12.x1 /CLONE=IMAGE:3702046 /UG=Hs.289068 Homo sapiens cDNA FLJ11918 fis, clone HEMBB1000272 BF433429 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212383_at AL096733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096733.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E071 (from clone DKFZp434E071). /FEA=mRNA /DB_XREF=gi:5419866 /UG=Hs.267871 ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110116kD) AL096733 ATPase, H+ transporting, lysosomal V0 subunit a1 ATP6V0A1 535 NM_001130020 /// NM_001130021 /// NM_005177 /// XM_005257459 /// XM_005257461 /// XM_005257463 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 212384_at AI282485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI282485 /FEA=EST /DB_XREF=gi:3920718 /DB_XREF=est:qu94b06.x1 /CLONE=IMAGE:1979699 /UG=Hs.55296 HLA-B associated transcript-1 AI282485 ATP6V1G2-DDX39B readthrough (NMD candidate) /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B /// small nucleolar RNA, C/D box 84 ATP6V1G2-DDX39B /// DDX39B /// SNORD84 7919 /// 692199 /// 100532737 NM_004640 /// NM_080598 /// NR_003065 /// NR_037852 /// NR_037853 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005688 // U6 snRNP // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0030621 // U4 snRNA binding // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212385_at AU118026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU118026 /FEA=EST /DB_XREF=gi:10933043 /DB_XREF=est:AU118026 /CLONE=HEMBA1002729 /UG=Hs.289068 Homo sapiens cDNA FLJ11918 fis, clone HEMBB1000272 AU118026 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212386_at BF592782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF592782 /FEA=EST /DB_XREF=gi:11685106 /DB_XREF=est:7j94d06.x1 /CLONE=IMAGE:3442594 /UG=Hs.289068 Homo sapiens cDNA FLJ11918 fis, clone HEMBB1000272 BF592782 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212387_at BG495771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG495771 /FEA=EST /DB_XREF=gi:13457287 /DB_XREF=est:602540396F1 /CLONE=IMAGE:4671599 /UG=Hs.289068 Homo sapiens cDNA FLJ11918 fis, clone HEMBB1000272 BG495771 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212388_at AB028980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028980.1 /DEF=Homo sapiens mRNA for KIAA1057 protein, partial cds. /FEA=mRNA /GEN=KIAA1057 /PROD=KIAA1057 protein /DB_XREF=gi:5689450 /UG=Hs.7243 ubiquitin specific protease 24 AB028980 ubiquitin specific peptidase 24 USP24 23358 NM_015306 /// XM_005270689 /// XM_005270690 /// XM_006710511 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 212389_at AW243200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW243200 /FEA=EST /DB_XREF=gi:6577007 /DB_XREF=est:xn29h07.x1 /CLONE=IMAGE:2695165 /UG=Hs.112049 SET binding factor 1 AW243200 SET binding factor 1 SBF1 6305 NM_002972 /// XM_005261931 /// XM_005261932 /// XM_005261934 /// XM_005261935 0006470 // protein dephosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 212390_at AB007923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007923.1 /DEF=Homo sapiens mRNA for KIAA0454 protein, partial cds. /FEA=mRNA /GEN=KIAA0454 /PROD=KIAA0454 protein /DB_XREF=gi:3413869 /UG=Hs.129928 KIAA0477 gene product AB007923 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 212391_x_at AI925635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI925635 /FEA=EST /DB_XREF=gi:5661686 /DB_XREF=est:wo34f07.x1 /CLONE=IMAGE:2457253 /UG=Hs.77039 ribosomal protein S3A AI925635 ribosomal protein S3A /// small nucleolar RNA, C/D box 73A RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212392_s_at AI950145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI950145 /FEA=EST /DB_XREF=gi:5742455 /DB_XREF=est:wp86b07.x1 /CLONE=IMAGE:2468629 /UG=Hs.129928 KIAA0477 gene product AI950145 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 212393_at AL096767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096767 /DEF=Human DNA sequence from clone 579N16 on chromosome 22. Contains the 3 part of the gene for KIAA0685, the SBF1 gene for SET binding factor 1, a novel gene, ESTs, an STS, GSSs and three putative CpG islands /FEA=mRNA_3 /DB_XREF=gi:5804920 /UG=Hs.112049 SET binding factor 1 AL096767 SET binding factor 1 SBF1 6305 NM_002972 /// XM_005261931 /// XM_005261932 /// XM_005261934 /// XM_005261935 0006470 // protein dephosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 212394_at D42044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D42044.1 /DEF=Human mRNA for KIAA0090 gene, partial cds. /FEA=mRNA /GEN=KIAA0090 /DB_XREF=gi:577300 /UG=Hs.154797 KIAA0090 protein D42044 ER membrane protein complex subunit 1 EMC1 23065 NM_001271427 /// NM_001271428 /// NM_001271429 /// NM_015047 /// XM_005245787 /// XM_005245788 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 212395_s_at BF197122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF197122 /FEA=EST /DB_XREF=gi:11086073 /DB_XREF=est:7l83b11.x1 /CLONE=IMAGE:3527781 /UG=Hs.154797 KIAA0090 protein BF197122 ER membrane protein complex subunit 1 EMC1 23065 NM_001271427 /// NM_001271428 /// NM_001271429 /// NM_015047 /// XM_005245787 /// XM_005245788 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 212396_s_at AI143233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI143233 /FEA=EST /DB_XREF=gi:3665042 /DB_XREF=est:qb76e09.x1 /CLONE=IMAGE:1706056 /UG=Hs.154797 KIAA0090 protein AI143233 ER membrane protein complex subunit 1 EMC1 23065 NM_001271427 /// NM_001271428 /// NM_001271429 /// NM_015047 /// XM_005245787 /// XM_005245788 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 212397_at AL137751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137751.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I0812 (from clone DKFZp434I0812); partial cds. /FEA=mRNA /GEN=DKFZp434I0812 /PROD=hypothetical protein /DB_XREF=gi:6808387 /UG=Hs.263671 Homo sapiens mRNA; cDNA DKFZp434I0812 (from clone DKFZp434I0812); partial cds AL137751 radixin RDX 5962 NM_001260492 /// NM_001260493 /// NM_001260494 /// NM_001260495 /// NM_001260496 /// NM_002906 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212398_at AI057093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI057093 /FEA=EST /DB_XREF=gi:3330969 /DB_XREF=est:oz23e12.x1 /CLONE=IMAGE:1676206 /UG=Hs.263671 Homo sapiens mRNA; cDNA DKFZp434I0812 (from clone DKFZp434I0812); partial cds AI057093 radixin RDX 5962 NM_001260492 /// NM_001260493 /// NM_001260494 /// NM_001260495 /// NM_001260496 /// NM_002906 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0030033 // microvillus assembly // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212399_s_at D50911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D50911.2 /DEF=Homo sapiens mRNA for KIAA0121 protein, partial cds. /FEA=mRNA /GEN=KIAA0121 /PROD=KIAA0121 protein /DB_XREF=gi:6633996 /UG=Hs.155584 KIAA0121 gene product D50911 vestigial-like family member 4 VGLL4 9686 NM_001128219 /// NM_001128220 /// NM_001128221 /// NM_001284390 /// NM_001284391 /// NM_014667 /// XM_006713423 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 212400_at AL043266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043266 /FEA=EST /DB_XREF=gi:5935844 /DB_XREF=est:DKFZp434L1423_s1 /CLONE=DKFZp434L1423 /UG=Hs.111334 ferritin, light polypeptide AL043266 family with sequence similarity 102, member A FAM102A 399665 NM_001035254 /// NM_203305 /// XM_005251984 212401_s_at AI767436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767436 /FEA=EST /DB_XREF=gi:5233865 /DB_XREF=est:wh25f07.x1 /CLONE=IMAGE:2381797 /UG=Hs.183418 cell division cycle 2-like 1 (PITSLRE proteins) AI767436 cyclin-dependent kinase 11A /// cyclin-dependent kinase 11B CDK11A /// CDK11B 984 /// 728642 NM_001291345 /// NM_001787 /// NM_024011 /// NM_033486 /// NM_033487 /// NM_033488 /// NM_033489 /// NM_033490 /// NM_033492 /// NM_033493 /// NM_033527 /// NM_033529 /// NM_033532 /// NM_033534 /// XM_006711061 /// XM_006711062 /// XM_006711063 /// XM_006711064 /// XM_006711065 /// XM_006711066 /// XM_006711067 /// XM_006711068 /// XM_006711069 /// XM_006711070 /// XM_006711071 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212402_at BE895685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE895685 /FEA=EST /DB_XREF=gi:10359330 /DB_XREF=est:601432693F1 /CLONE=IMAGE:3918046 /UG=Hs.136102 KIAA0853 protein BE895685 zinc finger CCCH-type containing 13 ZC3H13 23091 NM_015070 /// XM_005266301 /// XM_005266302 /// XM_005266303 /// XM_005266304 /// XM_005266305 /// XM_005266306 /// XM_005266307 /// XM_005266308 /// XM_005266309 /// XM_005266310 /// XM_005266311 /// XM_005266312 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212403_at AI749193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI749193 /FEA=EST /DB_XREF=gi:5127457 /DB_XREF=est:at40e04.x1 /CLONE=IMAGE:2374494 /UG=Hs.17639 Homo sapiens ubiquitin protein ligase (UBE3B) mRNA, partial cds AI749193 ubiquitin protein ligase E3B UBE3B 89910 NM_001270449 /// NM_001270450 /// NM_001270451 /// NM_130466 /// NM_183414 /// NM_183415 /// XM_005253987 /// XM_006719681 /// XM_006719682 /// XR_429118 /// XR_429119 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 212404_s_at AL096740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096740.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586K2123 (from clone DKFZp586K2123). /FEA=mRNA /DB_XREF=gi:5419896 /UG=Hs.17639 Homo sapiens ubiquitin protein ligase (UBE3B) mRNA, partial cds AL096740 ubiquitin protein ligase E3B UBE3B 89910 NM_001270449 /// NM_001270450 /// NM_001270451 /// NM_130466 /// NM_183414 /// NM_183415 /// XM_005253987 /// XM_006719681 /// XM_006719682 /// XR_429118 /// XR_429119 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 212405_s_at AK001172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001172.1 /DEF=Homo sapiens cDNA FLJ10310 fis, clone NT2RM2000322, highly similar to Homo sapiens mRNA for KIAA0859 protein. /FEA=mRNA /DB_XREF=gi:7022258 /UG=Hs.19469 KIAA0859 protein AK001172 methyltransferase like 13 METTL13 51603 NM_001007239 /// NM_014955 /// NM_015935 /// XM_005245256 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 212406_s_at AB028973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028973.1 /DEF=Homo sapiens mRNA for KIAA1050 protein, partial cds. /FEA=mRNA /GEN=KIAA1050 /PROD=KIAA1050 protein /DB_XREF=gi:5689436 /UG=Hs.184628 hypothetical protein FLJ10883 AB028973 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 PCMTD2 55251 NM_001104925 /// NM_018257 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212407_at AL049669 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049669.1 /DEF=Human gene from PAC 612B18, chromosome 1. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4678746 /UG=Hs.19469 KIAA0859 protein AL049669 methyltransferase like 13 METTL13 51603 NM_001007239 /// NM_014955 /// NM_015935 /// XM_005245256 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 212408_at AK023204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023204.1 /DEF=Homo sapiens cDNA FLJ13142 fis, clone NT2RP3003212, moderately similar to Rattus norvegicus lamina associated polypeptide 1C (LAP1C) mRNA. /FEA=mRNA /DB_XREF=gi:10435025 /UG=Hs.234265 DKFZP586G011 protein AK023204 torsin A interacting protein 1 TOR1AIP1 26092 NM_001267578 /// NM_015602 /// NM_032678 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0071763 // nuclear membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005521 // lamin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 212409_s_at AK021613 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021613.1 /DEF=Homo sapiens cDNA FLJ11551 fis, clone HEMBA1002999, moderately similar to Rattus norvegicus lamina associated polypeptide 1C (LAP1C) mRNA. /FEA=mRNA /DB_XREF=gi:10432828 /UG=Hs.234265 DKFZP586G011 protein AK021613 torsin A interacting protein 1 TOR1AIP1 26092 NM_001267578 /// NM_015602 /// NM_032678 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0071763 // nuclear membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005521 // lamin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 212410_at AI346431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346431 /FEA=EST /DB_XREF=gi:4083637 /DB_XREF=est:qp50g09.x1 /CLONE=IMAGE:1926496 /UG=Hs.75188 wee1+ (S. pombe) homolog AI346431 mitochondrial calcium uptake 2 MICU2 221154 NM_152726 /// XR_429214 0006851 // mitochondrial calcium ion transport // inferred from direct assay /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from electronic annotation /// 0051562 // negative regulation of mitochondrial calcium ion concentration // inferred from direct assay 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0034704 // calcium channel complex // inferred from sequence or structural similarity /// 1990246 // uniplex complex // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 212411_at BE747342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE747342 /FEA=EST /DB_XREF=gi:10161334 /DB_XREF=est:601580340F1 /CLONE=IMAGE:3929313 /UG=Hs.91579 Homo sapiens clone 23783 mRNA sequence BE747342 IMP4, U3 small nucleolar ribonucleoprotein IMP4 92856 NM_033416 /// XM_005263844 0006364 // rRNA processing // non-traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212412_at AV715767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV715767 /FEA=EST /DB_XREF=gi:10797284 /DB_XREF=est:AV715767 /CLONE=DCBATH02 /UG=Hs.7780 Homo sapiens mRNA; cDNA DKFZp564A072 (from clone DKFZp564A072) AV715767 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212413_at D50918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D50918.1 /DEF=Human mRNA for KIAA0128 gene, partial cds. /FEA=mRNA /GEN=KIAA0128 /DB_XREF=gi:1469178 /UG=Hs.90998 KIAA0128 protein; septin 2 D50918 septin 6 SEPT6 23157 NM_015129 /// NM_145799 /// NM_145800 /// NM_145802 /// XM_005262400 /// XM_006724748 /// XM_006724749 /// XM_006724750 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement 212414_s_at D50918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D50918.1 /DEF=Human mRNA for KIAA0128 gene, partial cds. /FEA=mRNA /GEN=KIAA0128 /DB_XREF=gi:1469178 /UG=Hs.90998 KIAA0128 protein; septin 2 D50918 glyoxylate reductase 1 homolog (Arabidopsis) /// septin 6 GLYR1 /// SEPT6 23157 /// 84656 NM_015129 /// NM_032569 /// NM_145799 /// NM_145800 /// NM_145802 /// XM_005255637 /// XM_005255638 /// XM_005255639 /// XM_005255640 /// XM_005262400 /// XM_006724748 /// XM_006724749 /// XM_006724750 /// XR_243321 0000910 // cytokinesis // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 212415_at AW150913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW150913 /FEA=EST /DB_XREF=gi:6198811 /DB_XREF=est:xg42a01.x1 /CLONE=IMAGE:2630184 /UG=Hs.90998 KIAA0128 protein; septin 2 AW150913 septin 6 SEPT6 23157 NM_015129 /// NM_145799 /// NM_145800 /// NM_145802 /// XM_005262400 /// XM_006724748 /// XM_006724749 /// XM_006724750 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement 212416_at AV745949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV745949 /FEA=EST /DB_XREF=gi:10865396 /DB_XREF=est:AV745949 /CLONE=NPABAE09 /UG=Hs.31218 secretory carrier membrane protein 1 AV745949 secretory carrier membrane protein 1 SCAMP1 9522 NM_001290229 /// NM_004866 /// NM_052822 /// NR_110885 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 212417_at BF058944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF058944 /FEA=EST /DB_XREF=gi:10812840 /DB_XREF=est:7k36c05.x1 /CLONE=IMAGE:3477489 /UG=Hs.31218 secretory carrier membrane protein 1 BF058944 secretory carrier membrane protein 1 SCAMP1 9522 NM_001290229 /// NM_004866 /// NM_052822 /// NR_110885 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 212418_at M82882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M82882.1 /DEF=Human cis-acting sequence. /FEA=mRNA /DB_XREF=gi:180551 /UG=Hs.154365 E74-like factor 1 (ets domain transcription factor) M82882 E74-like factor 1 (ets domain transcription factor) ELF1 1997 NM_001145353 /// NM_172373 /// XM_005266276 /// XM_005266277 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 212419_at AA131324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA131324 /FEA=EST /DB_XREF=gi:1693011 /DB_XREF=est:zl31b04.s1 /CLONE=IMAGE:503503 /UG=Hs.28264 Homo sapiens mRNA; cDNA DKFZp564L0822 (from clone DKFZp564L0822) AA131324 zinc finger, CCHC domain containing 24 ZCCHC24 219654 NM_153367 /// XM_005269604 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212420_at AL559590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL559590 /FEA=EST /DB_XREF=gi:12905223 /DB_XREF=est:AL559590 /CLONE=CS0DJ013YH24 (5 prime) /UG=Hs.154365 E74-like factor 1 (ets domain transcription factor) AL559590 E74-like factor 1 (ets domain transcription factor) ELF1 1997 NM_001145353 /// NM_172373 /// XM_005266276 /// XM_005266277 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 212421_at AB023147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023147.1 /DEF=Homo sapiens mRNA for KIAA0930 protein, partial cds. /FEA=mRNA /GEN=KIAA0930 /PROD=KIAA0930 protein /DB_XREF=gi:4589503 /UG=Hs.13255 KIAA0930 protein AB023147 KIAA0930 KIAA0930 23313 NM_001009880 /// NM_015264 212422_at AL547263 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL547263 /FEA=EST /DB_XREF=gi:12881179 /DB_XREF=est:AL547263 /CLONE=CS0DI007YI24 (5 prime) /UG=Hs.239499 KIAA0185 protein AL547263 programmed cell death 11 PDCD11 22984 NM_014976 /// XM_005269647 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212423_at AK024784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024784.1 /DEF=Homo sapiens cDNA: FLJ21131 fis, clone CAS06355. /FEA=mRNA /DB_XREF=gi:10437168 /UG=Hs.28264 Homo sapiens mRNA; cDNA DKFZp564L0822 (from clone DKFZp564L0822) AK024784 zinc finger, CCHC domain containing 24 ZCCHC24 219654 NM_153367 /// XM_005269604 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212424_at AW026194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW026194 /FEA=EST /DB_XREF=gi:5879735 /DB_XREF=est:wv09h07.x1 /CLONE=IMAGE:2529085 /UG=Hs.239499 KIAA0185 protein AW026194 programmed cell death 11 PDCD11 22984 NM_014976 /// XM_005269647 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212425_at AL049223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049223.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564L1916 (from clone DKFZp564L1916). /FEA=mRNA /DB_XREF=gi:4499953 /UG=Hs.31218 secretory carrier membrane protein 1 AL049223 secretory carrier membrane protein 1 SCAMP1 9522 NM_001290229 /// NM_004866 /// NM_052822 /// NR_110885 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 212426_s_at BF033313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF033313 /FEA=EST /DB_XREF=gi:10741025 /DB_XREF=est:601458002F1 /CLONE=IMAGE:3861457 /UG=Hs.74405 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide BF033313 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta YWHAQ 10971 NM_006826 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 212427_at AB002366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002366.1 /DEF=Human mRNA for KIAA0368 gene, partial cds. /FEA=mRNA /GEN=KIAA0368 /DB_XREF=gi:2224676 /UG=Hs.3852 KIAA0368 protein AB002366 KIAA0368 KIAA0368 23392 NM_001080398 /// XM_005251850 /// XM_005251851 /// XM_005251852 /// XM_005251853 /// XM_005251854 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 212428_at AW001101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW001101 /FEA=EST /DB_XREF=gi:5848017 /DB_XREF=est:wu24c05.x1 /CLONE=IMAGE:2520968 /UG=Hs.3852 KIAA0368 protein AW001101 KIAA0368 KIAA0368 23392 NM_001080398 /// XM_005251850 /// XM_005251851 /// XM_005251852 /// XM_005251853 /// XM_005251854 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 212429_s_at AW194657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194657 /FEA=EST /DB_XREF=gi:6473537 /DB_XREF=est:xb28b12.x1 /CLONE=IMAGE:2577599 /UG=Hs.75782 general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) AW194657 general transcription factor IIIC, polypeptide 2, beta 110kDa GTF3C2 2976 NM_001035521 /// NM_001521 /// XM_005264272 /// XM_005264273 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 212430_at AL109955 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109955 /DEF=Human DNA sequence from clone RP4-800J21 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands. Contains the 3 part of the RAE1 gene for a homolog to RNA export protein 1 from S.pombe and the gene for the ssDNA binding protein SEB4D.n /FEA=mRNA_1 /DB_XREF=gi:11558768 /UG=Hs.236361 seb4D AL109955 RNA binding motif protein 38 RBM38 55544 NM_001291780 /// NM_017495 /// NM_183425 /// XM_005260445 /// XM_005260446 0006397 // mRNA processing // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212431_at D83778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D83778.1 /DEF=Human mRNA for KIAA0194 gene, partial cds. /FEA=mRNA /GEN=KIAA0194 /DB_XREF=gi:1228038 /UG=Hs.216958 KIAA0194 protein D83778 HMG box domain containing 3 HMGXB3 22993 NM_014983 /// XM_006714765 /// XM_006714766 /// XM_006714767 0016310 // phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0016301 // kinase activity // non-traceable author statement 212432_at AL542571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL542571 /FEA=EST /DB_XREF=gi:12874746 /DB_XREF=est:AL542571 /CLONE=CS0DE012YH08 (5 prime) /UG=Hs.151903 GrpE-like protein cochaperone AL542571 GrpE-like 1, mitochondrial (E. coli) GRPEL1 80273 NM_025196 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0030150 // protein import into mitochondrial matrix // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay 0000774 // adenyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 212433_x_at AA630314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA630314 /FEA=EST /DB_XREF=gi:2552925 /DB_XREF=est:ac08f07.s1 /CLONE=IMAGE:855877 /UG=Hs.182426 ribosomal protein S2 AA630314 ribosomal protein S2 /// small nucleolar RNA, H/ACA box 64 RPS2 /// SNORA64 6187 /// 26784 NM_002952 /// NR_002326 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051347 // positive regulation of transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212434_at AI984421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984421 /FEA=EST /DB_XREF=gi:5811698 /DB_XREF=est:wr89a12.x1 /CLONE=IMAGE:2494846 /UG=Hs.151903 GrpE-like protein cochaperone AI984421 GrpE-like 1, mitochondrial (E. coli) GRPEL1 80273 NM_025196 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0030150 // protein import into mitochondrial matrix // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay 0000774 // adenyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 212435_at AA205593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA205593 /FEA=EST /DB_XREF=gi:1803601 /DB_XREF=est:zq68c06.s1 /CLONE=IMAGE:646762 /UG=Hs.26837 Homo sapiens mRNA; cDNA DKFZp586K1123 (from clone DKFZp586K1123) AA205593 tripartite motif containing 33 TRIM33 51592 NM_015906 /// NM_033020 /// XM_005270936 /// XM_005270937 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 212436_at AI967961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI967961 /FEA=EST /DB_XREF=gi:5764779 /DB_XREF=est:wu11d08.x1 /CLONE=IMAGE:2516655 /UG=Hs.26837 Homo sapiens mRNA; cDNA DKFZp586K1123 (from clone DKFZp586K1123) AI967961 tripartite motif containing 33 TRIM33 51592 NM_015906 /// NM_033020 /// XM_005270936 /// XM_005270937 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 212437_at AL109804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109804 /DEF=Human DNA sequence from clone RP5-1009E24 on chromosome 20 Contains a novel gene encoding two isoforms similar to mouse sialoadhesin (a macrophage sialic acid binding receptor), a novel gene similar to KIAA0417, the CENPB gene (centromere protein ... /FEA=mRNA_8 /DB_XREF=gi:11121192 /UG=Hs.85004 centromere protein B (80kD) AL109804 centromere protein B, 80kDa CENPB 1059 NM_001810 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // non-traceable author statement /// 0003696 // satellite DNA binding // non-traceable author statement /// 0019237 // centromeric DNA binding // inferred by curator /// 0043565 // sequence-specific DNA binding // traceable author statement 212438_at BG252325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG252325 /FEA=EST /DB_XREF=gi:12762141 /DB_XREF=est:602365913F1 /CLONE=IMAGE:4474082 /UG=Hs.54649 putative nucleic acid binding protein RY-1 BG252325 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) SNRNP27 11017 NM_006857 /// NR_037862 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212439_at BE614199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE614199 /FEA=EST /DB_XREF=gi:9895796 /DB_XREF=est:601504089T1 /CLONE=IMAGE:3905591 /UG=Hs.74579 KIAA0263 gene product BE614199 inositol hexakisphosphate kinase 1 IP6K1 9807 NM_001006115 /// NM_001242829 /// NM_153273 0016310 // phosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation 212440_at X76302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X76302.1 /DEF=H.sapiens RY-1 mRNA for putative nucleic acid binding protein. /FEA=mRNA /GEN=RY-1 /PROD=nucleic acid binding protein /DB_XREF=gi:431952 /UG=Hs.54649 putative nucleic acid binding protein RY-1 X76302 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) SNRNP27 11017 NM_006857 /// NR_037862 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212441_at D86985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D86985.2 /DEF=Homo sapiens mRNA for KIAA0232 protein, partial cds. /FEA=mRNA /GEN=KIAA0232 /PROD=KIAA0232 protein /DB_XREF=gi:6634002 /UG=Hs.79276 KIAA0232 gene product D86985 KIAA0232 KIAA0232 9778 NM_001100590 /// NM_014743 /// XM_005248041 /// XM_006713934 /// XM_006713935 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 212442_s_at BG289001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289001 /FEA=EST /DB_XREF=gi:13044404 /DB_XREF=est:602381262F1 /CLONE=IMAGE:4499078 /UG=Hs.101282 Homo sapiens cDNA: FLJ21238 fis, clone COL01115 BG289001 ceramide synthase 6 CERS6 253782 NM_001256126 /// NM_203463 /// XM_005246440 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0050291 // sphingosine N-acyltransferase activity // inferred from electronic annotation 212443_at AB011112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011112.2 /DEF=Homo sapiens mRNA for KIAA0540 protein, partial cds. /FEA=mRNA /GEN=KIAA0540 /PROD=KIAA0540 protein /DB_XREF=gi:6635198 /UG=Hs.64742 KIAA0540 protein AB011112 neurobeachin-like 2 NBEAL2 23218 NM_015175 /// XM_005264992 /// XM_005264993 /// XM_006713072 0030220 // platelet formation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212444_at AA156240 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156240 /FEA=EST /DB_XREF=gi:1727858 /DB_XREF=est:zl50c12.s1 /CLONE=IMAGE:505366 /UG=Hs.288660 Homo sapiens cDNA: FLJ22182 fis, clone HRC00953 AA156240 G protein-coupled receptor, class C, group 5, member A GPRC5A 9052 NM_003979 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 212445_s_at AI357376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357376 /FEA=EST /DB_XREF=gi:4108997 /DB_XREF=est:qy13a06.x1 /CLONE=IMAGE:2011858 /UG=Hs.12017 homolog of yeast ubiquitin-protein ligase Rsp5; potential epithelial sodium channel regulator AI357376 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase NEDD4L 23327 NM_001144964 /// NM_001144965 /// NM_001144966 /// NM_001144967 /// NM_001144968 /// NM_001144969 /// NM_001144970 /// NM_001144971 /// NM_001243960 /// NM_015277 /// XM_005266658 /// XM_005266660 /// XM_005266663 /// XM_006722421 /// XM_006722422 /// XM_006722423 /// XM_006722424 /// XM_006722425 /// XM_006722426 /// XM_006722427 /// XM_006722428 /// XM_006722429 /// XM_006722430 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006513 // protein monoubiquitination // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0006883 // cellular sodium ion homeostasis // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007588 // excretion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030104 // water homeostasis // non-traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042176 // regulation of protein catabolic process // non-traceable author statement /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902306 // negative regulation of sodium ion transmembrane transport // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay /// 2000650 // negative regulation of sodium ion transmembrane transporter activity // inferred from direct assay /// 2000810 // regulation of tight junction assembly // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation /// 2001288 // positive regulation of caveolin-mediated endocytosis // inferred from sequence or structural similarity 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0019871 // sodium channel inhibitor activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 212446_s_at AI658534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI658534 /FEA=EST /DB_XREF=gi:4762104 /DB_XREF=est:tu17g01.x1 /CLONE=IMAGE:2251344 /UG=Hs.101282 Homo sapiens cDNA: FLJ21238 fis, clone COL01115 AI658534 ceramide synthase 6 CERS6 253782 NM_001256126 /// NM_203463 /// XM_005246440 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0050291 // sphingosine N-acyltransferase activity // inferred from electronic annotation 212447_at AF161402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161402.1 /DEF=Homo sapiens HSPC284 mRNA, partial cds. /FEA=mRNA /PROD=HSPC284 /DB_XREF=gi:6841217 /UG=Hs.20237 DKFZP566C134 protein AF161402 kelch repeat and BTB (POZ) domain containing 2 KBTBD2 25948 NM_015483 /// XM_005249696 /// XM_005249697 0005515 // protein binding // inferred from electronic annotation 212448_at AB007899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007899.1 /DEF=Homo sapiens KIAA0439 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0439 /DB_XREF=gi:2662158 /UG=Hs.12017 homolog of yeast ubiquitin-protein ligase Rsp5; potential epithelial sodium channel regulator AB007899 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase NEDD4L 23327 NM_001144964 /// NM_001144965 /// NM_001144966 /// NM_001144967 /// NM_001144968 /// NM_001144969 /// NM_001144970 /// NM_001144971 /// NM_001243960 /// NM_015277 /// XM_005266658 /// XM_005266660 /// XM_005266663 /// XM_006722421 /// XM_006722422 /// XM_006722423 /// XM_006722424 /// XM_006722425 /// XM_006722426 /// XM_006722427 /// XM_006722428 /// XM_006722429 /// XM_006722430 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006513 // protein monoubiquitination // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0006883 // cellular sodium ion homeostasis // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007588 // excretion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030104 // water homeostasis // non-traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042176 // regulation of protein catabolic process // non-traceable author statement /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902306 // negative regulation of sodium ion transmembrane transport // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay /// 2000650 // negative regulation of sodium ion transmembrane transporter activity // inferred from direct assay /// 2000810 // regulation of tight junction assembly // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from electronic annotation /// 2001288 // positive regulation of caveolin-mediated endocytosis // inferred from sequence or structural similarity 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0019871 // sodium channel inhibitor activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 212449_s_at BG288007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG288007 /FEA=EST /DB_XREF=gi:13042412 /DB_XREF=est:602387785F1 /CLONE=IMAGE:4516701 /UG=Hs.12540 lysophospholipase I BG288007 lysophospholipase I LYPLA1 10434 NM_001279356 /// NM_001279357 /// NM_001279358 /// NM_001279359 /// NM_001279360 /// NM_006330 /// XM_005251127 /// XM_006716417 /// XR_428339 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004622 // lysophospholipase activity // traceable author statement /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 212450_at D87445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87445.2 /DEF=Homo sapiens mRNA for KIAA0256 protein, partial cds. /FEA=mRNA /GEN=KIAA0256 /PROD=KIAA0256 protein /DB_XREF=gi:6634006 /UG=Hs.118978 KIAA0256 gene product D87445 SECIS binding protein 2-like SECISBP2L 9728 NM_001193489 /// NM_014701 0044822 // poly(A) RNA binding // inferred from direct assay 212451_at N52532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N52532 /FEA=EST /DB_XREF=gi:1193698 /DB_XREF=est:yv35b11.s1 /CLONE=IMAGE:244701 /UG=Hs.118978 KIAA0256 gene product N52532 SECIS binding protein 2-like SECISBP2L 9728 NM_001193489 /// NM_014701 0044822 // poly(A) RNA binding // inferred from direct assay 212452_x_at AF113514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113514.1 /DEF=Homo sapiens histone acetyltransferase MORF mRNA, complete cds. /FEA=CDS /PROD=histone acetyltransferase MORF /DB_XREF=gi:6002685 /UG=Hs.27590 histone acetyltransferase /FL=gb:AF113514.1 AF113514 K(lysine) acetyltransferase 6B KAT6B 23522 NM_001256468 /// NM_001256469 /// NM_012330 /// XM_005269664 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212453_at AB033105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033105.1 /DEF=Homo sapiens mRNA for KIAA1279 protein, partial cds. /FEA=mRNA /GEN=KIAA1279 /PROD=KIAA1279 protein /DB_XREF=gi:6331321 /UG=Hs.172854 DKFZP586B0923 protein AB033105 KIAA1279 KIAA1279 26128 NM_015634 0006839 // mitochondrial transport // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction 212454_x_at AI762552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762552 /FEA=EST /DB_XREF=gi:5178219 /DB_XREF=est:wh92e10.x1 /CLONE=IMAGE:2388234 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like AI762552 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212455_at N36997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36997 /FEA=EST /DB_XREF=gi:1158139 /DB_XREF=est:yy39g07.s1 /CLONE=IMAGE:273660 /UG=Hs.12797 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 N36997 YTH domain containing 1 YTHDC1 91746 NM_001031732 /// NM_133370 /// XM_005265706 /// XM_005265707 /// XM_005265708 /// XM_005275637 /// XM_005275638 /// XM_005275639 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212456_at AB014564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014564.1 /DEF=Homo sapiens mRNA for KIAA0664 protein, partial cds. /FEA=mRNA /GEN=KIAA0664 /PROD=KIAA0664 protein /DB_XREF=gi:3327141 /UG=Hs.22616 KIAA0664 protein AB014564 clustered mitochondria (cluA/CLU1) homolog CLUH 23277 NM_015229 /// XM_005256565 /// XM_005256567 /// XM_005256568 /// XM_006721491 /// XM_006721492 0007005 // mitochondrion organization // inferred from electronic annotation /// 0048312 // intracellular distribution of mitochondria // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 212457_at AL161985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161985.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761J1810 (from clone DKFZp761J1810). /FEA=mRNA /DB_XREF=gi:7328121 /UG=Hs.274184 transcription factor binding to IGHM enhancer 3 AL161985 transcription factor binding to IGHM enhancer 3 TFE3 7030 NM_001282142 /// NM_006521 /// XM_006724549 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 212458_at H97931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H97931 /FEA=EST /DB_XREF=gi:1118816 /DB_XREF=est:yx04c02.s1 /CLONE=IMAGE:260738 /UG=Hs.173108 Homo sapiens cDNA: FLJ21897 fis, clone HEP03447, highly similar to AF052178 Homo sapiens clone 24523 mRNA sequence H97931 sprouty-related, EVH1 domain containing 2 SPRED2 200734 NM_001128210 /// NM_181784 /// XM_005264200 /// XM_005264201 /// XM_005264202 /// XM_006711966 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0090311 // regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005173 // stem cell factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity 212459_x_at BF593940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593940 /FEA=EST /DB_XREF=gi:11686264 /DB_XREF=est:nab48f10.x1 /CLONE=IMAGE:3269154 /UG=Hs.247309 succinate-CoA ligase, GDP-forming, beta subunit BF593940 succinate-CoA ligase, GDP-forming, beta subunit SUCLG2 8801 NM_001177599 /// NM_003848 /// XM_005264773 /// XR_245062 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // non-traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045244 // succinate-CoA ligase complex (GDP-forming) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004776 // succinate-CoA ligase (GDP-forming) activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212460_at BE738425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE738425 /FEA=EST /DB_XREF=gi:10152417 /DB_XREF=est:601572441T1 /CLONE=IMAGE:3839147 /UG=Hs.241507 ribosomal protein S6 BE738425 serine palmitoyltransferase, small subunit A SPTSSA 171546 NM_138288 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 212461_at BF793951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF793951 /FEA=EST /DB_XREF=gi:12099005 /DB_XREF=est:602254576F1 /CLONE=IMAGE:4346922 /UG=Hs.278614 protease, serine, 15 BF793951 antizyme inhibitor 1 AZIN1 51582 NM_015878 /// NM_148174 /// XM_005250969 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0042978 // ornithine decarboxylase activator activity // inferred from electronic annotation 212462_at AU144267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144267 /FEA=EST /DB_XREF=gi:11005788 /DB_XREF=est:AU144267 /CLONE=HEMBA1001396 /UG=Hs.27590 histone acetyltransferase /FL=gb:AF113514.1 AU144267 K(lysine) acetyltransferase 6B KAT6B 23522 NM_001256468 /// NM_001256469 /// NM_012330 /// XM_005269664 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212463_at BE379006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE379006 /FEA=EST /DB_XREF=gi:9324371 /DB_XREF=est:601236272F1 /CLONE=IMAGE:3608680 /UG=Hs.99766 Homo sapiens mRNA; cDNA DKFZp564J0323 (from clone DKFZp564J0323) BE379006 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 212464_s_at X02761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X02761.1 /DEF=Human mRNA for fibronectin (FN precursor). /FEA=mRNA /PROD=fibronectin precursor /DB_XREF=gi:31396 /UG=Hs.287820 fibronectin 1 X02761 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 212465_at AA524500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524500 /FEA=EST /DB_XREF=gi:2265428 /DB_XREF=est:ng45f12.s1 /CLONE=IMAGE:937775 /UG=Hs.321766 Homo sapiens cDNA: FLJ23027 fis, clone LNG01826 AA524500 SET domain containing 3 SETD3 84193 NM_032233 /// NM_199123 /// XM_005268126 /// XM_005268127 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010452 // histone H3-K36 methylation // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018022 // peptidyl-lysine methylation // inferred from electronic annotation /// 0018023 // peptidyl-lysine trimethylation // inferred from sequence or structural similarity /// 0018026 // peptidyl-lysine monomethylation // inferred from sequence or structural similarity /// 0018027 // peptidyl-lysine dimethylation // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from electronic annotation /// 0046975 // histone methyltransferase activity (H3-K36 specific) // inferred from sequence or structural similarity 212466_at AW138902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138902 /FEA=EST /DB_XREF=gi:6143220 /DB_XREF=est:UI-H-BI1-aeq-e-08-0-UI.s1 /CLONE=IMAGE:2720342 /UG=Hs.173108 Homo sapiens cDNA: FLJ21897 fis, clone HEP03447, highly similar to AF052178 Homo sapiens clone 24523 mRNA sequence AW138902 sprouty-related, EVH1 domain containing 2 SPRED2 200734 NM_001128210 /// NM_181784 /// XM_005264200 /// XM_005264201 /// XM_005264202 /// XM_006711966 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0090311 // regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005173 // stem cell factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity 212467_at AB014578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014578.1 /DEF=Homo sapiens mRNA for KIAA0678 protein, partial cds. /FEA=mRNA /GEN=KIAA0678 /PROD=KIAA0678 protein /DB_XREF=gi:3327169 /UG=Hs.12707 KIAA0678 protein AB014578 DnaJ (Hsp40) homolog, subfamily C, member 13 DNAJC13 23317 NM_015268 /// XM_005247245 0001649 // osteoblast differentiation // inferred from direct assay 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212468_at AK023512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023512.1 /DEF=Homo sapiens cDNA FLJ13450 fis, clone PLACE1003027, highly similar to Homo sapiens mRNA for KIAA0516 protein. /FEA=mRNA /DB_XREF=gi:10435467 /UG=Hs.129872 sperm associated antigen 9 AK023512 sperm associated antigen 9 SPAG9 9043 NM_001130527 /// NM_001130528 /// NM_001251971 /// NM_003971 /// NM_172345 /// XM_005257767 /// XM_005257768 /// XM_005257769 /// XM_005257770 /// XM_005257771 /// XM_005257772 /// XM_005257773 /// XM_005257774 /// XM_006722163 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from electronic annotation 212469_at AB019494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB019494.1 /DEF=Homo sapiens IDN3 mRNA, partial cds. /FEA=mRNA /GEN=IDN3 /DB_XREF=gi:4760548 /UG=Hs.225767 IDN3 protein AB019494 Nipped-B homolog (Drosophila) NIPBL 25836 NM_015384 /// NM_133433 /// XM_005248280 /// XM_005248282 /// XM_005248283 /// XM_006714467 /// XM_006714468 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001656 // metanephros development // non-traceable author statement /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0035261 // external genitalia morphogenesis // inferred from mutant phenotype /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from mutant phenotype /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0048638 // regulation of developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0061010 // gall bladder development // inferred from mutant phenotype /// 0061038 // uterus morphogenesis // inferred from mutant phenotype /// 0071481 // cellular response to X-ray // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070087 // chromo shadow domain binding // inferred from physical interaction 212470_at AB011088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011088.1 /DEF=Homo sapiens mRNA for KIAA0516 protein, partial cds. /FEA=mRNA /GEN=KIAA0516 /PROD=KIAA0516 protein /DB_XREF=gi:3043555 /UG=Hs.129872 sperm associated antigen 9 AB011088 sperm associated antigen 9 SPAG9 9043 NM_001130527 /// NM_001130528 /// NM_001251971 /// NM_003971 /// NM_172345 /// XM_005257767 /// XM_005257768 /// XM_005257769 /// XM_005257770 /// XM_005257771 /// XM_005257772 /// XM_005257773 /// XM_005257774 /// XM_006722163 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from electronic annotation 212471_at BE503381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE503381 /FEA=EST /DB_XREF=gi:9705789 /DB_XREF=est:7a17c02.x1 /CLONE=IMAGE:3218978 /UG=Hs.150275 KIAA0241 protein BE503381 AVL9 homolog (S. cerevisiase) AVL9 23080 NM_015060 /// XM_005249668 /// XM_005249669 /// XM_005249670 /// XM_005249671 0016477 // cell migration // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 212472_at BE965029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965029 /FEA=EST /DB_XREF=gi:11768976 /DB_XREF=est:601658812R1 /CLONE=IMAGE:3886131 /UG=Hs.198793 Homo sapiens cDNA: FLJ22463 fis, clone HRC10126 BE965029 microtubule associated monooxygenase, calponin and LIM domain containing 2 MICAL2 9645 NM_001282663 /// NM_001282664 /// NM_001282665 /// NM_001282666 /// NM_001282667 /// NM_001282668 /// NM_014632 /// XM_005253249 /// XM_005253251 /// XM_006718391 /// XM_006718392 /// XM_006718393 0001947 // heart looping // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from mutant phenotype /// 0019417 // sulfur oxidation // inferred from direct assay /// 0019417 // sulfur oxidation // inferred from sequence or structural similarity /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from sequence or structural similarity /// 0043914 // NADPH:sulfur oxidoreductase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity 212473_s_at BE965029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965029 /FEA=EST /DB_XREF=gi:11768976 /DB_XREF=est:601658812R1 /CLONE=IMAGE:3886131 /UG=Hs.198793 Homo sapiens cDNA: FLJ22463 fis, clone HRC10126 BE965029 microtubule associated monooxygenase, calponin and LIM domain containing 2 MICAL2 9645 NM_001282663 /// NM_001282664 /// NM_001282665 /// NM_001282666 /// NM_001282667 /// NM_001282668 /// NM_014632 /// XM_005253249 /// XM_005253251 /// XM_006718391 /// XM_006718392 /// XM_006718393 0001947 // heart looping // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from mutant phenotype /// 0019417 // sulfur oxidation // inferred from direct assay /// 0019417 // sulfur oxidation // inferred from sequence or structural similarity /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from sequence or structural similarity /// 0043914 // NADPH:sulfur oxidoreductase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity 212474_at D87682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87682.1 /DEF=Human mRNA for KIAA0241 gene, partial cds. /FEA=mRNA /GEN=KIAA0241 /DB_XREF=gi:1663699 /UG=Hs.150275 KIAA0241 protein D87682 AVL9 homolog (S. cerevisiase) AVL9 23080 NM_015060 /// XM_005249668 /// XM_005249669 /// XM_005249670 /// XM_005249671 0016477 // cell migration // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 212475_at AI797458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI797458 /FEA=EST /DB_XREF=gi:5362930 /DB_XREF=est:we88b10.x1 /CLONE=IMAGE:2348155 /UG=Hs.150275 KIAA0241 protein AI797458 AVL9 homolog (S. cerevisiase) AVL9 23080 NM_015060 /// XM_005249668 /// XM_005249669 /// XM_005249670 /// XM_005249671 0016477 // cell migration // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 212476_at D26069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D26069.1 /DEF=Human mRNA for KIAA0041 gene, partial cds. /FEA=mRNA /GEN=KIAA0041 /DB_XREF=gi:436227 /UG=Hs.24340 centaurin beta2 D26069 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 ACAP2 23527 NM_012287 /// XM_006713557 /// XM_006713558 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0036010 // protein localization to endosome // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212477_at D26069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D26069.1 /DEF=Human mRNA for KIAA0041 gene, partial cds. /FEA=mRNA /GEN=KIAA0041 /DB_XREF=gi:436227 /UG=Hs.24340 centaurin beta2 D26069 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 ACAP2 23527 NM_012287 /// XM_006713557 /// XM_006713558 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0036010 // protein localization to endosome // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212478_at H65865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H65865 /FEA=EST /DB_XREF=gi:1024605 /DB_XREF=est:yr75c09.s1 /CLONE=IMAGE:211120 /UG=Hs.75277 hypothetical protein FLJ13910 H65865 required for meiotic nuclear division 5 homolog A (S. cerevisiae) RMND5A 64795 NM_022780 0005515 // protein binding // inferred from electronic annotation 212479_s_at AK022815 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022815.1 /DEF=Homo sapiens cDNA FLJ12753 fis, clone NT2RP2001226. /FEA=mRNA /DB_XREF=gi:10434432 /UG=Hs.75277 hypothetical protein FLJ13910 AK022815 required for meiotic nuclear division 5 homolog A (S. cerevisiae) RMND5A 64795 NM_022780 0005515 // protein binding // inferred from electronic annotation 212480_at AB002374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002374.1 /DEF=Human mRNA for KIAA0376 gene, partial cds. /FEA=mRNA /GEN=KIAA0376 /DB_XREF=gi:2280484 /UG=Hs.4791 KIAA0376 protein AB002374 sperm antigen with calponin homology and coiled-coil domains 1-like SPECC1L 23384 NM_001145468 /// NM_001254732 /// NM_001254733 /// NM_015330 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030835 // negative regulation of actin filament depolymerization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212481_s_at AI214061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI214061 /FEA=EST /DB_XREF=gi:3777662 /DB_XREF=est:ap29d10.x1 /CLONE=IMAGE:1956787 /UG=Hs.250641 tropomyosin 4 AI214061 tropomyosin 4 TPM4 7171 NM_001145160 /// NM_003290 /// XM_005260042 /// XM_006722865 0001649 // osteoblast differentiation // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212482_at BF671894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF671894 /FEA=EST /DB_XREF=gi:11945789 /DB_XREF=est:602151796F1 /CLONE=IMAGE:4292999 /UG=Hs.75277 hypothetical protein FLJ13910 BF671894 required for meiotic nuclear division 5 homolog A (S. cerevisiae) RMND5A 64795 NM_022780 0005515 // protein binding // inferred from electronic annotation 212483_at AW339587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW339587 /FEA=EST /DB_XREF=gi:6836213 /DB_XREF=est:he14g08.x1 /CLONE=IMAGE:2919038 /UG=Hs.225767 IDN3 protein AW339587 Nipped-B homolog (Drosophila) NIPBL 25836 NM_015384 /// NM_133433 /// XM_005248280 /// XM_005248282 /// XM_005248283 /// XM_006714467 /// XM_006714468 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001656 // metanephros development // non-traceable author statement /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0035261 // external genitalia morphogenesis // inferred from mutant phenotype /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from mutant phenotype /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0048638 // regulation of developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0061010 // gall bladder development // inferred from mutant phenotype /// 0061038 // uterus morphogenesis // inferred from mutant phenotype /// 0071481 // cellular response to X-ray // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070087 // chromo shadow domain binding // inferred from physical interaction 212484_at BF974389 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF974389 /FEA=EST /DB_XREF=gi:12341604 /DB_XREF=est:602244063F1 /CLONE=IMAGE:4335182 /UG=Hs.18686 Mouse Mammary Turmor Virus Receptor homolog BF974389 family with sequence similarity 89, member B FAM89B 23625 NM_001098784 /// NM_001098785 /// NM_152832 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0060392 // negative regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation 0001222 // transcription corepressor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 212485_at AU146596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146596 /FEA=EST /DB_XREF=gi:11008117 /DB_XREF=est:AU146596 /CLONE=HEMBB1000938 /UG=Hs.105749 KIAA0553 protein AU146596 G patch domain containing 8 GPATCH8 23131 NM_001002909 /// NR_036474 /// XM_006721781 /// XM_006721782 /// XM_006721783 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212486_s_at N20923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N20923 /FEA=EST /DB_XREF=gi:1126093 /DB_XREF=est:yx53f09.s1 /CLONE=IMAGE:265481 /UG=Hs.169370 FYN oncogene related to SRC, FGR, YES N20923 FYN proto-oncogene, Src family tyrosine kinase FYN 2534 NM_001242779 /// NM_002037 /// NM_153047 /// NM_153048 /// XM_005266887 /// XM_005266888 /// XM_005266889 /// XM_005266890 /// XM_005266892 /// XM_006715429 0001764 // neuron migration // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007612 // learning // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 1900182 // positive regulation of protein localization to nucleus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042609 // CD4 receptor binding // inferred from electronic annotation /// 0042610 // CD8 receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation /// 0070851 // growth factor receptor binding // inferred from physical interaction 212487_at AI673812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI673812 /FEA=EST /DB_XREF=gi:4853543 /DB_XREF=est:to73f02.x1 /CLONE=IMAGE:2183931 /UG=Hs.105749 KIAA0553 protein AI673812 G patch domain containing 8 GPATCH8 23131 NM_001002909 /// NR_036474 /// XM_006721781 /// XM_006721782 /// XM_006721783 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212488_at N30339 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N30339 /FEA=EST /DB_XREF=gi:1148859 /DB_XREF=est:yw75f06.s1 /CLONE=IMAGE:258083 /UG=Hs.146428 collagen, type V, alpha 1 N30339 collagen, type V, alpha 1 COL5A1 1289 NM_000093 /// NM_001278074 0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 212489_at AI983428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983428 /FEA=EST /DB_XREF=gi:5810647 /DB_XREF=est:wt49a04.x1 /CLONE=IMAGE:2510766 /UG=Hs.146428 collagen, type V, alpha 1 AI983428 collagen, type V, alpha 1 COL5A1 1289 NM_000093 /// NM_001278074 0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 212490_at AA843895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA843895 /FEA=EST /DB_XREF=gi:2930346 /DB_XREF=est:ak09g10.s1 /CLONE=IMAGE:1405506 /UG=Hs.74711 DnaJ (Hsp40) homolog, subfamily C, member 8 AA843895 DnaJ (Hsp40) homolog, subfamily C, member 8 DNAJC8 22826 NM_014280 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005654 // nucleoplasm // traceable author statement 212491_s_at AA843895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA843895 /FEA=EST /DB_XREF=gi:2930346 /DB_XREF=est:ak09g10.s1 /CLONE=IMAGE:1405506 /UG=Hs.74711 DnaJ (Hsp40) homolog, subfamily C, member 8 AA843895 DnaJ (Hsp40) homolog, subfamily C, member 8 DNAJC8 22826 NM_014280 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005654 // nucleoplasm // traceable author statement 212492_s_at AW237172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW237172 /FEA=EST /DB_XREF=gi:6569561 /DB_XREF=est:xm66e04.x1 /CLONE=IMAGE:2689182 /UG=Hs.301011 KIAA0876 protein AW237172 lysine (K)-specific demethylase 4B KDM4B 23030 NM_015015 /// XM_005259521 /// XM_005259522 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212493_s_at AI761110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761110 /FEA=EST /DB_XREF=gi:5176777 /DB_XREF=est:wi69h02.x1 /CLONE=IMAGE:2398611 /UG=Hs.6947 HSPC069 protein AI761110 SET domain containing 2 SETD2 29072 NM_012271 /// NM_014159 /// XM_005265094 /// XM_006713119 /// XM_006713120 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0010452 // histone H3-K36 methylation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018023 // peptidyl-lysine trimethylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034728 // nucleosome organization // inferred from mutant phenotype /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035441 // cell migration involved in vasculogenesis // inferred from electronic annotation /// 0048332 // mesoderm morphogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048864 // stem cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0097198 // histone H3-K36 trimethylation // inferred from direct assay /// 0097198 // histone H3-K36 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046914 // transition metal ion binding // inferred from electronic annotation 212494_at AB028998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028998.1 /DEF=Homo sapiens mRNA for KIAA1075 protein, partial cds. /FEA=mRNA /GEN=KIAA1075 /PROD=KIAA1075 protein /DB_XREF=gi:5689486 /UG=Hs.6147 KIAA1075 protein AB028998 tensin like C1 domain containing phosphatase (tensin 2) TENC1 23371 NM_015319 /// NM_170754 /// NM_198316 /// XM_006719302 /// XM_006719303 /// XM_006719304 0001822 // kidney development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048871 // multicellular organismal homeostasis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212495_at BE256900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE256900 /FEA=EST /DB_XREF=gi:9127367 /DB_XREF=est:601112063F1 /CLONE=IMAGE:3352887 /UG=Hs.301011 KIAA0876 protein BE256900 lysine (K)-specific demethylase 4B KDM4B 23030 NM_015015 /// XM_005259521 /// XM_005259522 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212496_s_at BE256900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE256900 /FEA=EST /DB_XREF=gi:9127367 /DB_XREF=est:601112063F1 /CLONE=IMAGE:3352887 /UG=Hs.301011 KIAA0876 protein BE256900 lysine (K)-specific demethylase 4B KDM4B 23030 NM_015015 /// XM_005259521 /// XM_005259522 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212497_at AI554879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI554879 /FEA=EST /DB_XREF=gi:4487242 /DB_XREF=est:te53e03.x1 /CLONE=IMAGE:2090428 /UG=Hs.81360 Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence AI554879 mitogen-activated protein kinase 1 interacting protein 1-like MAPK1IP1L 93487 NM_144578 212498_at AF056433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF056433.1 /DEF=Homo sapiens clone FBD3 Cri-du-chat critical region mRNA. /FEA=mRNA /DB_XREF=gi:3044151 /UG=Hs.8078 Homo sapiens clone FBD3 Cri-du-chat critical region mRNA AF056433 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212499_s_at AK025580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025580.1 /DEF=Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10438139 /UG=Hs.81360 Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence AK025580 FCF1 rRNA-processing protein /// mitogen-activated protein kinase 1 interacting protein 1-like FCF1 /// MAPK1IP1L 51077 /// 93487 NM_015962 /// NM_144578 /// XM_005267730 /// XM_005267731 /// XR_245689 /// XR_245690 /// XR_245691 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 212500_at AL049319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049319.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C046 (from clone DKFZp564C046). /FEA=mRNA /DB_XREF=gi:4500092 /UG=Hs.99821 Homo sapiens mRNA; cDNA DKFZp564C046 (from clone DKFZp564C046) AL049319 2-aminoethanethiol (cysteamine) dioxygenase ADO 84890 NM_032804 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047800 // cysteamine dioxygenase activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212501_at AL564683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL564683 /FEA=EST /DB_XREF=gi:12915335 /DB_XREF=est:AL564683 /CLONE=CS0DM007YK12 (3 prime) /UG=Hs.99029 CCAATenhancer binding protein (CEBP), beta /FL=gb:NM_005194.1 AL564683 CCAAT/enhancer binding protein (C/EBP), beta CEBPB 1051 NM_001285878 /// NM_001285879 /// NM_005194 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006953 // acute-phase response // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045408 // regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212502_at AV713053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV713053 /FEA=EST /DB_XREF=gi:10732372 /DB_XREF=est:AV713053 /CLONE=DCAADD03 /UG=Hs.99821 Homo sapiens mRNA; cDNA DKFZp564C046 (from clone DKFZp564C046) AV713053 2-aminoethanethiol (cysteamine) dioxygenase ADO 84890 NM_032804 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047800 // cysteamine dioxygenase activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212503_s_at N22859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N22859 /FEA=EST /DB_XREF=gi:1137009 /DB_XREF=est:yx56d09.s1 /CLONE=IMAGE:265745 /UG=Hs.227716 KIAA0934 protein N22859 DIP2 disco-interacting protein 2 homolog C (Drosophila) DIP2C 22982 NM_014974 /// XM_005252426 /// XM_005252427 /// XM_005252428 /// XM_005252429 /// XM_005252430 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation 212504_at N31807 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N31807 /FEA=EST /DB_XREF=gi:1152206 /DB_XREF=est:yy17b09.s1 /CLONE=IMAGE:271481 /UG=Hs.227716 KIAA0934 protein N31807 DIP2 disco-interacting protein 2 homolog C (Drosophila) DIP2C 22982 NM_014974 /// XM_005252426 /// XM_005252427 /// XM_005252428 /// XM_005252429 /// XM_005252430 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation 212505_s_at AL110250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110250.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P101 (from clone DKFZp434P101); partial cds. /FEA=mRNA /GEN=DKFZp434P101 /PROD=hypothetical protein /DB_XREF=gi:5817201 /UG=Hs.112751 KIAA0892 protein AL110250 MAU2 sister chromatid cohesion factor MAU2 23383 NM_015329 /// XM_005259837 /// XM_005259838 /// XM_006722711 /// XR_430132 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0032116 // SMC loading complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 212506_at AL135735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL135735 /FEA=EST /DB_XREF=gi:6603922 /DB_XREF=est:DKFZp586N0217_s1 /CLONE=DKFZp586N0217 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein AL135735 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 212507_at D87446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87446.1 /DEF=Human mRNA for KIAA0257 gene, partial cds. /FEA=mRNA /GEN=KIAA0257 /DB_XREF=gi:1665780 /UG=Hs.75912 KIAA0257 protein D87446 transmembrane protein 131 TMEM131 23505 NM_015348 /// XM_005263909 /// XM_005263910 /// XM_005263911 /// XM_005263912 /// XR_427080 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212508_at AK024029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024029.1 /DEF=Homo sapiens cDNA FLJ13967 fis, clone Y79AA1001402, weakly similar to Homo sapiens paraneoplastic cancer-testis-brain antigen (MA4) mRNA. /FEA=mRNA /DB_XREF=gi:10436287 /UG=Hs.24719 modulator of apoptosis 1 /FL=gb:AF305550.1 gb:NM_022151.1 AK024029 modulator of apoptosis 1 MOAP1 64112 NM_022151 0001844 // protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // inferred from direct assay /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 212509_s_at BF968134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF968134 /FEA=EST /DB_XREF=gi:12335349 /DB_XREF=est:602269121F1 /CLONE=IMAGE:4357349 /UG=Hs.250723 FK506 binding protein 12-rapamycin associated protein 1 BF968134 matrix-remodelling associated 7 MXRA7 439921 NM_001008528 /// NM_001008529 /// NM_198530 /// XM_005257382 /// XM_005257383 /// XM_005257384 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212510_at AA135522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA135522 /FEA=EST /DB_XREF=gi:1696570 /DB_XREF=est:zl09d08.s1 /CLONE=IMAGE:501423 /UG=Hs.82432 KIAA0089 protein AA135522 glycerol-3-phosphate dehydrogenase 1-like GPD1L 23171 NM_015141 /// XM_005264983 /// XM_005264984 /// XM_006713068 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from mutant phenotype /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019674 // NAD metabolic process // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046168 // glycerol-3-phosphate catabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0090038 // negative regulation of protein kinase C signaling // inferred from mutant phenotype /// 2000010 // positive regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009331 // glycerol-3-phosphate dehydrogenase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004367 // glycerol-3-phosphate dehydrogenase [NAD+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 212511_at AI766247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI766247 /FEA=EST /DB_XREF=gi:5232756 /DB_XREF=est:wh68f03.x1 /CLONE=IMAGE:2385917 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein AI766247 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 212512_s_at AA551784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA551784 /FEA=EST /DB_XREF=gi:2322036 /DB_XREF=est:nf99f01.s1 /CLONE=IMAGE:928057 /UG=Hs.143696 coactivator-associated arginine methyltransferase-1 AA551784 coactivator-associated arginine methyltransferase 1 CARM1 10498 NM_199141 /// XM_005259708 0003420 // regulation of growth plate cartilage chondrocyte proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0033146 // regulation of intracellular estrogen receptor signaling pathway // inferred from sequence or structural similarity /// 0034969 // histone arginine methylation // inferred from electronic annotation /// 0034970 // histone H3-R2 methylation // inferred from mutant phenotype /// 0034971 // histone H3-R17 methylation // inferred from sequence or structural similarity /// 0035246 // peptidyl-arginine N-methylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060350 // endochondral bone morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from sequence or structural similarity /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from sequence or structural similarity /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // inferred from sequence or structural similarity /// 0035642 // histone methyltransferase activity (H3-R17 specific) // inferred from sequence or structural similarity /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 212513_s_at AB029020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029020.1 /DEF=Homo sapiens mRNA for KIAA1097 protein, partial cds. /FEA=mRNA /GEN=KIAA1097 /PROD=KIAA1097 protein /DB_XREF=gi:5689530 /UG=Hs.173694 KIAA1097 protein AB029020 ubiquitin specific peptidase 33 USP33 23032 NM_015017 /// NM_201624 /// NM_201626 /// XM_005270648 /// XM_005270649 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from mutant phenotype /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030891 // VCB complex // traceable author statement /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212514_x_at R60068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R60068 /FEA=EST /DB_XREF=gi:830763 /DB_XREF=est:yh12h07.s1 /CLONE=IMAGE:43138 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 R60068 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 212515_s_at BG492602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG492602 /FEA=EST /DB_XREF=gi:13454114 /DB_XREF=est:602536568F1 /CLONE=IMAGE:4655296 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 BG492602 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 212516_at AB018325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018325.1 /DEF=Homo sapiens mRNA for KIAA0782 protein, partial cds. /FEA=mRNA /GEN=KIAA0782 /PROD=KIAA0782 protein /DB_XREF=gi:3882284 /UG=Hs.21264 KIAA0782 protein AB018325 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ARAP1 116985 NM_001040118 /// NM_001135190 /// NM_015242 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030037 // actin filament reorganization involved in cell cycle // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051270 // regulation of cellular component movement // inferred from mutant phenotype /// 0051491 // positive regulation of filopodium assembly // inferred from mutant phenotype /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212517_at AL132773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL132773 /DEF=Human DNA sequence from clone RP4-741H3 on chromosome 20 Contains parts of isoform 1 and isoform 2 (KIAA0548) of the ATRN (attractin (with dipeptidylpeptidase IV activity)) gene, ESTs, STSs and GSSs /FEA=mRNA_1 /DB_XREF=gi:7159777 /UG=Hs.194019 attractin AL132773 attractin ATRN 8455 NM_001207047 /// NM_012070 /// NM_139321 /// NM_139322 /// XM_005260860 /// XM_005260861 0006954 // inflammatory response // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 212518_at AB011161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011161.1 /DEF=Homo sapiens mRNA for KIAA0589 protein, partial cds. /FEA=mRNA /GEN=KIAA0589 /PROD=KIAA0589 protein /DB_XREF=gi:3043701 /UG=Hs.275182 phosphatidylinositol-4-phosphate 5-kinase, type I, gamma AB011161 phosphatidylinositol-4-phosphate 5-kinase, type I, gamma PIP5K1C 23396 NM_001195733 /// NM_012398 /// XM_005259523 /// XM_006722712 /// XR_430133 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006909 // phagocytosis // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016079 // synaptic vesicle exocytosis // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0034333 // adherens junction assembly // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0070527 // platelet aggregation // inferred from electronic annotation /// 0072583 // clathrin-mediated endocytosis // traceable author statement 0001891 // phagocytic cup // inferred from electronic annotation /// 0001931 // uropod // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 1990147 // talin binding // inferred from electronic annotation 212519_at AL518159 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL518159 /FEA=EST /DB_XREF=gi:12781652 /DB_XREF=est:AL518159 /CLONE=CS0DA010YD02 (5 prime) /UG=Hs.7766 ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC45) /FL=gb:NM_003341.1 AL518159 ubiquitin-conjugating enzyme E2E 1 UBE2E1 7324 NM_001202476 /// NM_003341 /// NM_182666 /// XM_005265431 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0042296 // ISG15 ligase activity // inferred from direct assay 212520_s_at AI684141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI684141 /FEA=EST /DB_XREF=gi:4895435 /DB_XREF=est:tx79f11.x1 /CLONE=IMAGE:2275821 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AI684141 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212521_s_at BE568219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE568219 /FEA=EST /DB_XREF=gi:9811939 /DB_XREF=est:601341764F1 /CLONE=IMAGE:3683966 /UG=Hs.78746 phosphodiesterase 8A BE568219 phosphodiesterase 8A PDE8A 5151 NM_001243137 /// NM_002605 /// NM_173454 /// NM_173455 /// NM_173456 /// NM_173457 /// XM_005254933 /// XM_006720567 /// XM_006720568 /// XR_429456 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000156 // phosphorelay response regulator activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212522_at W73272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W73272 /FEA=EST /DB_XREF=gi:1383407 /DB_XREF=est:zd54g09.s1 /CLONE=IMAGE:344512 /UG=Hs.78746 phosphodiesterase 8A W73272 phosphodiesterase 8A PDE8A 5151 NM_001243137 /// NM_002605 /// NM_173454 /// NM_173455 /// NM_173456 /// NM_173457 /// XM_005254933 /// XM_006720567 /// XM_006720568 /// XR_429456 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000156 // phosphorelay response regulator activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212523_s_at D63480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D63480.1 /DEF=Human mRNA for KIAA0146 gene, partial cds. /FEA=mRNA /GEN=KIAA0146 /DB_XREF=gi:1469873 /UG=Hs.278634 KIAA0146 protein D63480 scaffolding protein involved in DNA repair SPIDR 23514 NM_001080394 /// NM_001282916 /// NM_001282919 /// NR_104581 /// XM_005251189 /// XM_005251191 /// XM_005251193 /// XM_005251195 /// XM_005251196 /// XM_005251197 /// XM_005251198 /// XM_005251199 /// XM_005251201 /// XM_006716443 /// XM_006716444 /// XM_006716445 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0070202 // regulation of establishment of protein localization to chromosome // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072711 // cellular response to hydroxyurea // inferred from direct assay /// 0072757 // cellular response to camptothecin // inferred from direct assay /// 2000781 // positive regulation of double-strand break repair // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212524_x_at BE901081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE901081 /FEA=EST /DB_XREF=gi:10389901 /DB_XREF=est:601674431F1 /CLONE=IMAGE:3957319 /UG=Hs.147097 H2A histone family, member X BE901081 H2A histone family, member X H2AFX 3014 NM_002105 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // non-traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010212 // response to ionizing radiation // non-traceable author statement /// 0045739 // positive regulation of DNA repair // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212525_s_at AA760862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA760862 /FEA=EST /DB_XREF=gi:2809792 /DB_XREF=est:nz14g12.s1 /CLONE=IMAGE:1287814 /UG=Hs.147097 H2A histone family, member X AA760862 H2A histone family, member X H2AFX 3014 NM_002105 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // non-traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010212 // response to ionizing radiation // non-traceable author statement /// 0045739 // positive regulation of DNA repair // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // inferred from electronic annotation /// 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212526_at AK002207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002207.1 /DEF=Homo sapiens cDNA FLJ11345 fis, clone PLACE1010877, highly similar to Homo sapiens mRNA for KIAA0610 protein. /FEA=mRNA /DB_XREF=gi:7023938 /UG=Hs.118087 KIAA0610 protein AK002207 spastic paraplegia 20 (Troyer syndrome) SPG20 23111 NM_001142294 /// NM_001142295 /// NM_001142296 /// NM_015087 /// XM_005266313 /// XM_005266314 /// XM_005266315 /// XM_005266316 /// XM_005266317 0000910 // cytokinesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009838 // abscission // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from electronic annotation /// 0048698 // negative regulation of collateral sprouting in absence of injury // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0060612 // adipose tissue development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 212527_at BF057059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057059 /FEA=EST /DB_XREF=gi:10810955 /DB_XREF=est:7k15c07.x1 /CLONE=IMAGE:3444468 /UG=Hs.12421 hypothetical protein BF057059 desumoylating isopeptidase 1 DESI1 27351 NM_015704 /// XM_005261571 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 212528_at AI348009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348009 /FEA=EST /DB_XREF=gi:4085215 /DB_XREF=est:qp61b09.x1 /CLONE=IMAGE:1927481 /UG=Hs.12421 hypothetical protein AI348009 desumoylating isopeptidase 1 DESI1 27351 NM_015704 /// XM_005261571 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 212529_at BF197707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF197707 /FEA=EST /DB_XREF=gi:11087054 /DB_XREF=est:7m96h03.x1 /CLONE=IMAGE:3562997 /UG=Hs.155485 huntingtin interacting protein 2 BF197707 LSM12 homolog (S. cerevisiae) LSM12 124801 NM_152344 212530_at AL080111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080111.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586G2222 (from clone DKFZp586G2222). /FEA=mRNA /DB_XREF=gi:5262538 /UG=Hs.24119 Homo sapiens mRNA; cDNA DKFZp586G2222 (from clone DKFZp586G2222) AL080111 NIMA-related kinase 7 NEK7 140609 NM_133494 0000910 // cytokinesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007346 // regulation of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051225 // spindle assembly // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212531_at NM_005564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005564.1 /DEF=Homo sapiens lipocalin 2 (oncogene 24p3) (LCN2), mRNA. /FEA=CDS /GEN=LCN2 /PROD=lipocalin 2 (oncogene 24p3) /DB_XREF=gi:5031852 /UG=Hs.204238 lipocalin 2 (oncogene 24p3) /FL=gb:NM_005564.1 NM_005564 lipocalin 2 LCN2 3934 NM_005564 0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0015891 // siderophore transport // inferred from sequence or structural similarity /// 0031346 // positive regulation of cell projection organization // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 212532_s_at AW873564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW873564 /FEA=EST /DB_XREF=gi:8007617 /DB_XREF=est:ho62c10.x1 /CLONE=IMAGE:3041970 /UG=Hs.155485 huntingtin interacting protein 2 AW873564 LSM12 homolog (S. cerevisiae) LSM12 124801 NM_152344 212533_at X62048 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X62048.1 /DEF=H.sapiens Wee1 hu gene. /FEA=mRNA /GEN=Wee1 Hu /DB_XREF=gi:499071 /UG=Hs.75188 wee1+ (S. pombe) homolog /FL=gb:NM_003390.1 gb:U10564.1 X62048 WEE1 G2 checkpoint kinase WEE1 7465 NM_001143976 /// NM_003390 /// XM_005253118 /// XM_005253119 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212534_at AU144066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144066 /FEA=EST /DB_XREF=gi:11005587 /DB_XREF=est:AU144066 /CLONE=HEMBA1000798 /UG=Hs.285519 Homo sapiens cDNA FLJ11904 fis, clone HEMBB1000048 AU144066 zinc finger protein 24 ZNF24 7572 NM_006965 /// XM_005258341 /// XM_005258342 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212535_at AA142929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA142929 /FEA=EST /DB_XREF=gi:1712307 /DB_XREF=est:zl40g07.s1 /CLONE=IMAGE:504444 /UG=Hs.288993 ESTs AA142929 myocyte enhancer factor 2A MEF2A 4205 NM_001130926 /// NM_001130927 /// NM_001130928 /// NM_001171894 /// NM_005587 /// XM_005254914 /// XM_005254915 /// XM_005254916 /// XM_006720509 /// XM_006720510 /// XM_006720511 /// XM_006720512 /// XM_006720513 /// XM_006720514 /// XM_006720515 /// XM_006720516 /// XM_006720517 /// XM_006720518 /// XM_006720519 /// XM_006720520 /// XM_006720521 0000002 // mitochondrial genome maintenance // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from direct assay /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003138 // primary heart field specification // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003185 // sinoatrial valve morphogenesis // inferred from electronic annotation /// 0003211 // cardiac ventricle formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048311 // mitochondrion distribution // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0055005 // ventricular cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0061333 // renal tubule morphogenesis // inferred from electronic annotation /// 0061337 // cardiac conduction // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from electronic annotation /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from electronic annotation /// 0072160 // nephron tubule epithelial cell differentiation // inferred from electronic annotation /// 0090073 // positive regulation of protein homodimerization activity // inferred from electronic annotation /// 2000111 // positive regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 212536_at AB023173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023173.1 /DEF=Homo sapiens mRNA for KIAA0956 protein, partial cds. /FEA=mRNA /GEN=KIAA0956 /PROD=KIAA0956 protein /DB_XREF=gi:4589555 /UG=Hs.75478 ATPase, Class VI, type 11B AB023173 ATPase, class VI, type 11B ATP11B 23200 NM_014616 /// XM_005247241 /// XM_005247242 /// XM_005247243 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0015917 // aminophospholipid transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005637 // nuclear inner membrane // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212537_x_at BE733979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE733979 /FEA=EST /DB_XREF=gi:10147971 /DB_XREF=est:601571007F1 /CLONE=IMAGE:3925800 /UG=Hs.82202 ribosomal protein L17 BE733979 chromosome 18 open reading frame 32 /// ribosomal protein L17 /// RPL17-C18orf32 readthrough /// small nucleolar RNA, C/D box 58A /// small nucleolar RNA, C/D box 58B /// small nucleolar RNA, C/D box 58C C18orf32 /// RPL17 /// RPL17-C18orf32 /// SNORD58A /// SNORD58B /// SNORD58C 6139 /// 26790 /// 26791 /// 497661 /// 100124516 /// 100526842 NM_000985 /// NM_001035005 /// NM_001035006 /// NM_001199340 /// NM_001199341 /// NM_001199342 /// NM_001199343 /// NM_001199344 /// NM_001199345 /// NM_001199346 /// NM_001199355 /// NM_001199356 /// NR_002571 /// NR_002572 /// NR_003701 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 212538_at AL576253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL576253 /FEA=EST /DB_XREF=gi:12938214 /DB_XREF=est:AL576253 /CLONE=CS0DI073YM22 (3 prime) /UG=Hs.8021 KIAA1058 protein AL576253 dedicator of cytokinesis 9 DOCK9 23348 NM_001130048 /// NM_001130049 /// NM_001130050 /// NM_015296 /// XM_005254034 /// XM_005254035 /// XM_005254036 /// XM_006719922 /// XM_006719923 /// XM_006719924 /// XM_006719925 /// XM_006719926 /// XM_006719927 /// XM_006719928 /// XM_006719929 /// XM_006719930 /// XM_006719931 /// XM_006719932 /// XM_006719933 /// XM_006719934 /// XM_006719935 /// XM_006719936 /// XM_006719937 /// XM_006719938 /// XM_006719939 /// XM_006719940 /// XM_006719941 /// XM_006719942 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation 212539_at AI422099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI422099 /FEA=EST /DB_XREF=gi:4268030 /DB_XREF=est:tf57h09.x1 /CLONE=IMAGE:2103425 /UG=Hs.14570 hypothetical protein FLJ22530 AI422099 chromodomain helicase DNA binding protein 1-like CHD1L 9557 NM_001256336 /// NM_001256337 /// NM_001256338 /// NM_004284 /// NM_024568 /// NR_046070 /// XM_006711636 /// XM_006711637 /// XM_006711638 /// XM_006711639 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from mutant phenotype 212540_at BG476661 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG476661 /FEA=EST /DB_XREF=gi:13408940 /DB_XREF=est:602524946F1 /CLONE=IMAGE:4643458 /UG=Hs.76932 cell division cycle 34 BG476661 cell division cycle 34 CDC34 997 NM_004359 /// XM_005259690 /// XM_006722952 0000082 // G1/S transition of mitotic cell cycle // non-traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0006270 // DNA replication initiation // non-traceable author statement /// 0006464 // cellular protein modification process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // non-traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0070848 // response to growth factor // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0090261 // positive regulation of inclusion body assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 212541_at AL562282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL562282 /FEA=EST /DB_XREF=gi:12910548 /DB_XREF=est:AL562282 /CLONE=CS0DC003YN02 (3 prime) /UG=Hs.118666 hypothetical protein PP591 AL562282 flavin adenine dinucleotide synthetase 1 FLAD1 80308 NM_001184891 /// NM_001184892 /// NM_025207 /// NM_201398 /// XM_005245502 /// XM_005245503 /// XM_006711557 /// XM_006711558 /// XM_006711559 /// XR_241098 /// XR_426798 0006747 // FAD biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003919 // FMN adenylyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 212542_s_at BF224151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224151 /FEA=EST /DB_XREF=gi:11131400 /DB_XREF=est:7q84c02.x1 /CLONE=IMAGE:3704835 /UG=Hs.10177 hypothetical protein FLJ20705 BF224151 pleckstrin homology domain interacting protein PHIP 55023 NM_017934 /// XM_005248729 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005158 // insulin receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212543_at U83115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U83115.1 /DEF=Human non-lens beta gamma-crystallin like protein (AIM1) mRNA, partial cds. /FEA=mRNA /GEN=AIM1 /PROD=non-lens beta gamma-crystallin like protein /DB_XREF=gi:2072424 /UG=Hs.161002 absent in melanoma 1 U83115 absent in melanoma 1 AIM1 202 NM_001624 /// XM_005266839 212544_at AI131008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI131008 /FEA=EST /DB_XREF=gi:3601024 /DB_XREF=est:qc15h06.x1 /CLONE=IMAGE:1709723 /UG=Hs.2210 thyroid hormone receptor interactor 3 AI131008 zinc finger, HIT-type containing 3 ZNHIT3 9326 NM_001033577 /// NM_001281432 /// NM_001281433 /// NM_001281434 /// NM_004773 /// NR_104009 /// NR_104010 /// NR_104011 0006355 // regulation of transcription, DNA-templated // traceable author statement 0005622 // intracellular // non-traceable author statement 0046872 // metal ion binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // traceable author statement 212545_s_at AW292783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW292783 /FEA=EST /DB_XREF=gi:6699419 /DB_XREF=est:UI-H-BW0-aij-e-03-0-UI.s1 /CLONE=IMAGE:2729549 /UG=Hs.167839 KIAA0395 protein AW292783 zinc fingers and homeoboxes 3 ZHX3 23051 NM_015035 /// XM_005260341 /// XM_005260343 /// XM_006723747 /// XM_006723748 /// XM_006723749 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 212546_s_at AI126634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI126634 /FEA=EST /DB_XREF=gi:3595148 /DB_XREF=est:qd83b10.x1 /CLONE=IMAGE:1736059 /UG=Hs.169600 KIAA0826 protein AI126634 FRY-like FRYL 285527 NM_001039751 /// NM_015030 /// XM_005248082 /// XM_005248083 /// XM_005248084 /// XM_005248085 /// XM_005248086 /// XM_005248087 /// XM_005248088 /// XM_005248089 /// XM_005248090 /// XM_005248091 /// XM_005248093 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212547_at N34842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N34842 /FEA=EST /DB_XREF=gi:1155984 /DB_XREF=est:yy45d11.s1 /CLONE=IMAGE:276501 /UG=Hs.6580 Homo sapiens cDNA: FLJ23227 fis, clone CAE00645, highly similar to AF052138 Homo sapiens clone 23718 mRNA sequence N34842 bromodomain containing 3 BRD3 8019 NM_007371 /// XM_005272214 /// XM_006717291 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 212548_s_at BF515124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF515124 /FEA=EST /DB_XREF=gi:11600303 /DB_XREF=est:UI-H-BW1-anv-f-02-0-UI.s1 /CLONE=IMAGE:3083666 /UG=Hs.169600 KIAA0826 protein BF515124 FRY-like FRYL 285527 NM_001039751 /// NM_015030 /// XM_005248082 /// XM_005248083 /// XM_005248084 /// XM_005248085 /// XM_005248086 /// XM_005248087 /// XM_005248088 /// XM_005248089 /// XM_005248090 /// XM_005248091 /// XM_005248093 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212549_at BE645861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645861 /FEA=EST /DB_XREF=gi:9970172 /DB_XREF=est:7e77d05.x1 /CLONE=IMAGE:3288489 /UG=Hs.24064 Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) BE645861 signal transducer and activator of transcription 5B STAT5B 6777 NM_012448 /// XM_005257625 /// XM_005257626 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0001553 // luteinization // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042448 // progesterone metabolic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046543 // development of secondary female sexual characteristics // inferred from electronic annotation /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070669 // response to interleukin-2 // inferred from electronic annotation /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 0070672 // response to interleukin-15 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 212550_at AI149535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI149535 /FEA=EST /DB_XREF=gi:3678004 /DB_XREF=est:qc70f11.x1 /CLONE=IMAGE:1714989 /UG=Hs.24064 Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) AI149535 signal transducer and activator of transcription 5B STAT5B 6777 NM_012448 /// XM_005257625 /// XM_005257626 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0001553 // luteinization // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0042448 // progesterone metabolic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046543 // development of secondary female sexual characteristics // inferred from electronic annotation /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070669 // response to interleukin-2 // inferred from electronic annotation /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 0070672 // response to interleukin-15 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity 212551_at NM_006366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006366.1 /DEF=Homo sapiens adenylyl cyclase-associated protein 2 (CAP2), mRNA. /FEA=CDS /GEN=CAP2 /PROD=adenylyl cyclase-associated protein 2 /DB_XREF=gi:5453592 /UG=Hs.296341 adenylyl cyclase-associated protein 2 /FL=gb:U02390.1 gb:NM_006366.1 NM_006366 CAP, adenylate cyclase-associated protein, 2 (yeast) CAP2 10486 NM_006366 0000902 // cell morphogenesis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 212552_at BE617588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE617588 /FEA=EST /DB_XREF=gi:9888526 /DB_XREF=est:601441509T1 /CLONE=IMAGE:3845643 /UG=Hs.3618 hippocalcin-like 1 BE617588 hippocalcin-like 1 HPCAL1 3241 NM_001258357 /// NM_001258358 /// NM_001258359 /// NM_002149 /// NM_134421 /// XM_005246160 /// XM_005246161 /// XM_005246162 /// XM_005246163 /// XM_006711885 /// XR_426955 0007165 // signal transduction // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212553_at AK026120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026120.1 /DEF=Homo sapiens cDNA: FLJ22467 fis, clone HRC10345. /FEA=mRNA /DB_XREF=gi:10438867 /UG=Hs.29956 KIAA0460 protein AK026120 regulation of nuclear pre-mRNA domain containing 2 RPRD2 23248 NM_015203 /// XM_005245031 /// XM_005245032 /// XM_005245033 /// XM_006711240 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay 212554_at N90755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N90755 /FEA=EST /DB_XREF=gi:1444082 /DB_XREF=est:zb22c08.s1 /CLONE=IMAGE:302798 /UG=Hs.296341 adenylyl cyclase-associated protein 2 /FL=gb:U02390.1 gb:NM_006366.1 N90755 CAP, adenylate cyclase-associated protein, 2 (yeast) CAP2 10486 NM_006366 0000902 // cell morphogenesis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 212555_at AI814660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814660 /FEA=EST /DB_XREF=gi:5425875 /DB_XREF=est:wj75g12.x1 /CLONE=IMAGE:2408710 /UG=Hs.1519 protein kinase, cAMP-dependent, regulatory, type I, beta AI814660 protein kinase, cAMP-dependent, regulatory, type I, beta PRKAR1B 5575 NM_001164758 /// NM_001164759 /// NM_001164760 /// NM_001164761 /// NM_001164762 /// NM_002735 /// XM_005249809 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 212556_at AI469403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI469403 /FEA=EST /DB_XREF=gi:4331493 /DB_XREF=est:tm08c12.x1 /CLONE=IMAGE:2155990 /UG=Hs.239784 human homolog of Drosophila Scribble AI469403 scribbled planar cell polarity protein SCRIB 23513 NM_015356 /// NM_182706 0001843 // neural tube closure // inferred from mutant phenotype /// 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008105 // asymmetric protein localization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from genetic interaction /// 0016477 // cell migration // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0035089 // establishment of apical/basal cell polarity // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from mutant phenotype /// 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 0060603 // mammary gland duct morphogenesis // inferred from sequence or structural similarity /// 0071896 // protein localization to adherens junction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0034750 // Scrib-APC-beta-catenin complex // inferred from direct assay /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212557_at AB011148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011148.1 /DEF=Homo sapiens mRNA for KIAA0576 protein, partial cds. /FEA=mRNA /GEN=KIAA0576 /PROD=KIAA0576 protein /DB_XREF=gi:3043675 /UG=Hs.172329 KIAA0576 protein AB011148 zinc finger protein 451 ZNF451 26036 NM_001031623 /// NM_001257273 /// NM_015555 /// XM_005248994 /// XR_241885 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212558_at BF508662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508662 /FEA=EST /DB_XREF=gi:11591960 /DB_XREF=est:UI-H-BI4-aop-c-11-0-UI.s1 /CLONE=IMAGE:3085461 /UG=Hs.88044 sprouty (Drosophila) homolog 1 (antagonist of FGF signaling) BF508662 sprouty homolog 1, antagonist of FGF signaling (Drosophila) SPRY1 10252 NM_001258038 /// NM_001258039 /// NM_005841 /// NM_199327 /// XM_005262686 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0034261 // negative regulation of Ras GTPase activity // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 212559_at AU148827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148827 /FEA=EST /DB_XREF=gi:11010348 /DB_XREF=est:AU148827 /CLONE=NT2RM4001027 /UG=Hs.1519 protein kinase, cAMP-dependent, regulatory, type I, beta AU148827 protein kinase, cAMP-dependent, regulatory, type I, beta PRKAR1B 5575 NM_001164758 /// NM_001164759 /// NM_001164760 /// NM_001164761 /// NM_001164762 /// NM_002735 /// XM_005249809 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 212560_at AV728268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV728268 /FEA=EST /DB_XREF=gi:10837689 /DB_XREF=est:AV728268 /CLONE=HTCACH05 /UG=Hs.82845 Homo sapiens cDNA: FLJ21930 fis, clone HEP04301, highly similar to HSU90916 Human clone 23815 mRNA sequence AV728268 sortilin-related receptor, L(DLR class) A repeats containing SORL1 6653 NM_003105 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006622 // protein targeting to lysosome // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032460 // negative regulation of protein oligomerization // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045053 // protein retention in Golgi apparatus // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from direct assay /// 0070863 // positive regulation of protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from sequence or structural similarity /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902771 // positive regulation of choline O-acetyltransferase activity // inferred from sequence or structural similarity /// 1902948 // negative regulation of tau-protein kinase activity // inferred from sequence or structural similarity /// 1902953 // positive regulation of ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 1902955 // positive regulation of early endosome to recycling endosome transport // inferred from mutant phenotype /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from direct assay /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902966 // positive regulation of protein localization to early endosome // inferred from mutant phenotype /// 1902997 // negative regulation of neurofibrillary tangle assembly // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction 212561_at AA349595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA349595 /FEA=EST /DB_XREF=gi:2001934 /DB_XREF=est:EST56429 /UG=Hs.26797 KIAA1091 protein AA349595 DENN/MADD domain containing 5A DENND5A 23258 NM_001243254 /// NM_015213 /// XM_005252832 /// XM_006718169 /// XR_242782 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // not recorded 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // not recorded 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from electronic annotation 212562_s_at AA418800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA418800 /FEA=EST /DB_XREF=gi:2080647 /DB_XREF=est:zw01d09.s1 /CLONE=IMAGE:768017 /UG=Hs.252549 cathepsin Z AA418800 cathepsin Z CTSZ 1522 NM_001336 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008234 // cysteine-type peptidase activity // inferred from electronic annotation 212563_at BG491842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG491842 /FEA=EST /DB_XREF=gi:13453354 /DB_XREF=est:602535929T1 /CLONE=IMAGE:4684902 /UG=Hs.30736 KIAA0124 protein BG491842 block of proliferation 1 /// microRNA 7112 BOP1 /// MIR7112 23246 /// 102465906 NM_015201 /// NR_107057 0000463 // maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0000466 // maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0042254 // ribosome biogenesis // inferred by curator /// 0042254 // ribosome biogenesis // non-traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030687 // preribosome, large subunit precursor // inferred from electronic annotation /// 0070545 // PeBoW complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212564_at AA523921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA523921 /FEA=EST /DB_XREF=gi:2264849 /DB_XREF=est:ni90f08.s1 /CLONE=IMAGE:984135 /UG=Hs.4935 KIAA0176 protein AA523921 potassium channel tetramerization domain containing 2 KCTD2 23510 NM_015353 /// NR_110834 /// NR_110835 /// XR_243758 /// XR_248405 /// XR_253732 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 212565_at BE302191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE302191 /FEA=EST /DB_XREF=gi:9185939 /DB_XREF=est:bb82f05.x1 /CLONE=IMAGE:3048897 /UG=Hs.184523 KIAA0965 protein BE302191 serine/threonine kinase 38 like STK38L 23012 NM_015000 /// XM_005253342 /// XM_005253343 /// XM_006719058 /// XM_006719059 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0051128 // regulation of cellular component organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212566_at AL523310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523310 /FEA=EST /DB_XREF=gi:12786803 /DB_XREF=est:AL523310 /CLONE=CS0DC001YN06 (3 prime) /UG=Hs.150580 putative translation initiation factor AL523310 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212567_s_at AL523310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523310 /FEA=EST /DB_XREF=gi:12786803 /DB_XREF=est:AL523310 /CLONE=CS0DC001YN06 (3 prime) /UG=Hs.150580 putative translation initiation factor AL523310 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212568_s_at BF978872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF978872 /FEA=EST /DB_XREF=gi:12346087 /DB_XREF=est:602149330F2 /CLONE=IMAGE:4308247 /UG=Hs.115285 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) BF978872 dihydrolipoamide S-acetyltransferase DLAT 1737 NM_001931 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006085 // acetyl-CoA biosynthetic process // non-traceable author statement /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // non-traceable author statement /// 0045254 // pyruvate dehydrogenase complex // inferred from electronic annotation 0004742 // dihydrolipoyllysine-residue acetyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 212569_at AV699744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV699744 /FEA=EST /DB_XREF=gi:10301715 /DB_XREF=est:AV699744 /CLONE=GKCEDF05 /UG=Hs.8118 KIAA0650 protein AV699744 structural maintenance of chromosomes flexible hinge domain containing 1 SMCHD1 23347 NM_015295 /// XM_005258102 /// XM_006722321 /// XR_430039 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0060821 // inactivation of X chromosome by DNA methylation // inferred from electronic annotation 0001740 // Barr body // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 212570_at AL573201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL573201 /FEA=EST /DB_XREF=gi:12932211 /DB_XREF=est:AL573201 /CLONE=CS0DI043YM01 (3 prime) /UG=Hs.167115 KIAA0830 protein AL573201 endonuclease domain containing 1 ENDOD1 23052 NM_015036 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212571_at U00955 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U00955.1 /DEF=Human clone CE29 8.1 (CAC)n(GTG)n repeat-containing mRNA. /FEA=mRNA /DB_XREF=gi:405057 /UG=Hs.173421 KIAA1564 protein U00955 chromodomain helicase DNA binding protein 8 CHD8 57680 NM_001170629 /// NM_020920 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0043044 // ATP-dependent chromatin remodeling // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003678 // DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from sequence or structural similarity /// 0070016 // armadillo repeat domain binding // inferred from electronic annotation 212572_at AW779556 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW779556 /FEA=EST /DB_XREF=gi:7794159 /DB_XREF=est:hn81f05.x1 /CLONE=IMAGE:3034305 /UG=Hs.184523 KIAA0965 protein AW779556 serine/threonine kinase 38 like STK38L 23012 NM_015000 /// XM_005253342 /// XM_005253343 /// XM_006719058 /// XM_006719059 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0051128 // regulation of cellular component organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212573_at AF131747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131747.1 /DEF=Homo sapiens clone 24951 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406562 /UG=Hs.167115 KIAA0830 protein AF131747 endonuclease domain containing 1 ENDOD1 23052 NM_015036 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212574_x_at AC004528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004528 /DEF=Homo sapiens chromosome 19, cosmid R32184 /FEA=CDS_2 /DB_XREF=gi:3025444 /UG=Hs.280666 Homo sapiens chromosome 19, cosmid R32184 AC004528 transmembrane protein 259 TMEM259 91304 NM_001033026 /// NM_033420 /// XM_005259675 /// XM_005259676 /// XM_005259677 /// XM_005259678 /// XM_005259679 /// XR_244044 /// XR_430159 /// XR_430160 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212575_at BF966155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF966155 /FEA=EST /DB_XREF=gi:12333370 /DB_XREF=est:602286439F1 /CLONE=IMAGE:4375473 /UG=Hs.280666 Homo sapiens chromosome 19, cosmid R32184 BF966155 transmembrane protein 259 TMEM259 91304 NM_001033026 /// NM_033420 /// XM_005259675 /// XM_005259676 /// XM_005259677 /// XM_005259678 /// XM_005259679 /// XR_244044 /// XR_430159 /// XR_430160 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212576_at AB011116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011116.1 /DEF=Homo sapiens mRNA for KIAA0544 protein, partial cds. /FEA=mRNA /GEN=KIAA0544 /PROD=KIAA0544 protein /DB_XREF=gi:3043611 /UG=Hs.284251 KIAA0544 protein AB011116 mahogunin ring finger 1, E3 ubiquitin protein ligase MGRN1 23295 NM_001142289 /// NM_001142290 /// NM_001142291 /// NM_015246 /// NR_102267 /// XM_005255217 /// XM_005255218 /// XM_005255219 /// XM_005255220 /// XM_005255221 /// XM_006720871 /// XR_429639 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212577_at AA868754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA868754 /FEA=EST /DB_XREF=gi:2964199 /DB_XREF=est:ak52e09.s1 /CLONE=IMAGE:1409608 /UG=Hs.8118 KIAA0650 protein AA868754 structural maintenance of chromosomes flexible hinge domain containing 1 SMCHD1 23347 NM_015295 /// XM_005258102 /// XM_006722321 /// XR_430039 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0060821 // inactivation of X chromosome by DNA methylation // inferred from electronic annotation 0001740 // Barr body // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 212578_x_at BF026595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF026595 /FEA=EST /DB_XREF=gi:10734307 /DB_XREF=est:601672736F1 /CLONE=IMAGE:3955617 /UG=Hs.5174 ribosomal protein S17 BF026595 ribosomal protein S17 RPS17 6218 NM_001021 /// NM_001199057 /// NR_111943 /// NR_111944 0000028 // ribosomal small subunit assembly // not recorded /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // not recorded /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212579_at AB014550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014550.1 /DEF=Homo sapiens mRNA for KIAA0650 protein, partial cds. /FEA=mRNA /GEN=KIAA0650 /PROD=KIAA0650 protein /DB_XREF=gi:3327113 /UG=Hs.8118 KIAA0650 protein AB014550 structural maintenance of chromosomes flexible hinge domain containing 1 SMCHD1 23347 NM_015295 /// XM_005258102 /// XM_006722321 /// XR_430039 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0060821 // inactivation of X chromosome by DNA methylation // inferred from electronic annotation 0001740 // Barr body // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 212580_at BG111635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG111635 /FEA=EST /DB_XREF=gi:12605141 /DB_XREF=est:602282681F1 /CLONE=IMAGE:4369844 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator BG111635 calpastatin CAST 831 NM_001042440 /// NM_001042441 /// NM_001042442 /// NM_001042443 /// NM_001042444 /// NM_001042445 /// NM_001042446 /// NM_001190442 /// NM_001284212 /// NM_001284213 /// NM_001750 /// NM_173060 /// NM_173061 /// NM_173062 /// NM_173063 /// NR_033798 /// NR_104285 /// XM_006714696 /// XM_006714697 /// XM_006714698 /// XM_006714699 /// XM_006714700 /// XM_006714701 /// XM_006714702 /// XM_006714703 /// XM_006714704 /// XM_006714705 /// XM_006714706 /// XM_006714707 /// XM_006714708 /// XM_006714709 /// XM_006714710 /// XM_006714711 /// XM_006714712 /// XM_006714713 /// XM_006714714 /// XM_006714715 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010859 // calcium-dependent cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212581_x_at BE561479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE561479 /FEA=EST /DB_XREF=gi:9805199 /DB_XREF=est:601346543F1 /CLONE=IMAGE:3679498 /UG=Hs.169476 glyceraldehyde-3-phosphate dehydrogenase BE561479 glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 212582_at AL049923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049923.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E2282 (from clone DKFZp564E2282). /FEA=mRNA /DB_XREF=gi:4884169 /UG=Hs.109694 KIAA1451 protein AL049923 oxysterol binding protein-like 8 OSBPL8 114882 NM_001003712 /// NM_020841 /// XM_005268621 /// XM_005268622 /// XM_005268623 /// XM_006719222 /// XM_006719223 /// XM_006719224 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0090204 // protein localization to nuclear pore // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 212583_at AB011132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011132.2 /DEF=Homo sapiens mRNA for KIAA0560 protein, partial cds. /FEA=mRNA /GEN=KIAA0560 /PROD=KIAA0560 protein /DB_XREF=gi:6635202 /UG=Hs.129952 KIAA0560 gene product AB011132 aquarius intron-binding spliceosomal factor AQR 9716 NM_014691 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097157 // pre-mRNA intronic binding // inferred from electronic annotation 212584_at BG260519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG260519 /FEA=EST /DB_XREF=gi:12770335 /DB_XREF=est:602372065F1 /CLONE=IMAGE:4480024 /UG=Hs.129952 KIAA0560 gene product BG260519 aquarius intron-binding spliceosomal factor AQR 9716 NM_014691 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097157 // pre-mRNA intronic binding // inferred from electronic annotation 212585_at BF970829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF970829 /FEA=EST /DB_XREF=gi:12338044 /DB_XREF=est:602271468F1 /CLONE=IMAGE:4359593 /UG=Hs.109694 KIAA1451 protein BF970829 oxysterol binding protein-like 8 OSBPL8 114882 NM_001003712 /// NM_020841 /// XM_005268621 /// XM_005268622 /// XM_005268623 /// XM_006719222 /// XM_006719223 /// XM_006719224 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0090204 // protein localization to nuclear pore // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 212586_at AA195244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA195244 /FEA=EST /DB_XREF=gi:1784944 /DB_XREF=est:zr36b02.s1 /CLONE=IMAGE:665451 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator AA195244 calpastatin CAST 831 NM_001042440 /// NM_001042441 /// NM_001042442 /// NM_001042443 /// NM_001042444 /// NM_001042445 /// NM_001042446 /// NM_001190442 /// NM_001284212 /// NM_001284213 /// NM_001750 /// NM_173060 /// NM_173061 /// NM_173062 /// NM_173063 /// NR_033798 /// NR_104285 /// XM_006714696 /// XM_006714697 /// XM_006714698 /// XM_006714699 /// XM_006714700 /// XM_006714701 /// XM_006714702 /// XM_006714703 /// XM_006714704 /// XM_006714705 /// XM_006714706 /// XM_006714707 /// XM_006714708 /// XM_006714709 /// XM_006714710 /// XM_006714711 /// XM_006714712 /// XM_006714713 /// XM_006714714 /// XM_006714715 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010859 // calcium-dependent cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212587_s_at AI809341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI809341 /FEA=EST /DB_XREF=gi:5395907 /DB_XREF=est:we96c09.x1 /CLONE=IMAGE:2348944 /UG=Hs.170121 protein tyrosine phosphatase, receptor type, C AI809341 protein tyrosine phosphatase, receptor type, C PTPRC 5788 NM_001267798 /// NM_002838 /// NM_080921 /// NM_080922 /// NR_052021 /// XM_006711472 /// XM_006711473 /// XM_006711474 /// XM_006711475 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from mutant phenotype /// 0002378 // immunoglobulin biosynthetic process // inferred from mutant phenotype /// 0002711 // positive regulation of T cell mediated immunity // inferred from electronic annotation /// 0002923 // regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from mutant phenotype /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045577 // regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // non-traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0048539 // bone marrow development // inferred from mutant phenotype /// 0048864 // stem cell development // inferred from mutant phenotype /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050855 // regulation of B cell receptor signaling pathway // inferred from electronic annotation /// 0050857 // positive regulation of antigen receptor-mediated signaling pathway // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 2000473 // positive regulation of hematopoietic stem cell migration // inferred from mutant phenotype /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 212588_at Y00062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y00062.1 /DEF=Human mRNA for T200 leukocyte common antigen (CD45, LC-A). /FEA=mRNA /DB_XREF=gi:34275 /UG=Hs.170121 protein tyrosine phosphatase, receptor type, C Y00062 protein tyrosine phosphatase, receptor type, C PTPRC 5788 NM_001267798 /// NM_002838 /// NM_080921 /// NM_080922 /// NR_052021 /// XM_006711472 /// XM_006711473 /// XM_006711474 /// XM_006711475 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from mutant phenotype /// 0002378 // immunoglobulin biosynthetic process // inferred from mutant phenotype /// 0002711 // positive regulation of T cell mediated immunity // inferred from electronic annotation /// 0002923 // regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from mutant phenotype /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045577 // regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // non-traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0048539 // bone marrow development // inferred from mutant phenotype /// 0048864 // stem cell development // inferred from mutant phenotype /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050855 // regulation of B cell receptor signaling pathway // inferred from electronic annotation /// 0050857 // positive regulation of antigen receptor-mediated signaling pathway // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 2000473 // positive regulation of hematopoietic stem cell migration // inferred from mutant phenotype /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 212589_at AI753792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI753792 /FEA=EST /DB_XREF=gi:5132144 /DB_XREF=est:cr16f06.x2 /CLONE=HBMSC_cr16f06 /UG=Hs.206097 oncogene TC21 AI753792 related RAS viral (r-ras) oncogene homolog 2 RRAS2 22800 NM_001102669 /// NM_001177314 /// NM_001177315 /// NM_012250 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 212590_at AI431643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI431643 /FEA=EST /DB_XREF=gi:4304619 /DB_XREF=est:tg74f12.x1 /CLONE=IMAGE:2114543 /UG=Hs.206097 oncogene TC21 AI431643 related RAS viral (r-ras) oncogene homolog 2 RRAS2 22800 NM_001102669 /// NM_001177314 /// NM_001177315 /// NM_012250 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 212591_at AA887480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA887480 /FEA=EST /DB_XREF=gi:3003168 /DB_XREF=est:oj54a12.s1 /CLONE=IMAGE:1502110 /UG=Hs.17428 RBP1-like protein AA887480 AT rich interactive domain 4B (RBP1-like) /// RNA binding motif protein 34 ARID4B /// RBM34 23029 /// 51742 NM_001161533 /// NM_001206794 /// NM_015014 /// NM_016374 /// NM_031371 /// NR_027762 /// XM_005273160 /// XM_006711781 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation /// 0036124 // histone H3-K9 trimethylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212592_at AV733266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV733266 /FEA=EST /DB_XREF=gi:10850811 /DB_XREF=est:AV733266 /CLONE=cdAAJG04 /UG=Hs.76325 step II splicing factor SLU7 AV733266 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides IGJ 3512 NM_144646 /// XM_006714211 /// XM_006714212 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0032461 // positive regulation of protein oligomerization // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071750 // dimeric IgA immunoglobulin complex // inferred from mutant phenotype /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0019862 // IgA binding // inferred from mutant phenotype /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 212593_s_at N92498 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92498 /FEA=EST /DB_XREF=gi:1264807 /DB_XREF=est:zb28a04.s1 /CLONE=IMAGE:304878 /UG=Hs.326248 Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 N92498 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212594_at AI185160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI185160 /FEA=EST /DB_XREF=gi:3735798 /DB_XREF=est:qe30g10.s1 /CLONE=IMAGE:1740546 /UG=Hs.326248 Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 AI185160 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212595_s_at AL534321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL534321 /FEA=EST /DB_XREF=gi:12797814 /DB_XREF=est:AL534321 /CLONE=CS0DF004YB03 (5 prime) /UG=Hs.75416 DAZ associated protein 2 AL534321 DAZ associated protein 2 DAZAP2 9802 NM_001136264 /// NM_001136266 /// NM_001136267 /// NM_001136268 /// NM_001136269 /// NM_014764 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 212596_s_at AJ010070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ010070.1 /DEF=Homo sapiens mRNA encompasing THC211630. /FEA=mRNA /DB_XREF=gi:3483014 /UG=Hs.92260 high-mobility group protein 2-like 1 AJ010070 HMG box domain containing 4 HMGXB4 10042 NM_001003681 /// NM_005487 /// NM_014250 /// NR_027780 /// XM_006724100 /// XM_006724101 /// XM_006724102 0008333 // endosome to lysosome transport // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0016589 // NURF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 212597_s_at AL079310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079310.1 /DEF=Novel human gene mapping to chomosome 22. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:5102629 /UG=Hs.92260 high-mobility group protein 2-like 1 AL079310 HMG box domain containing 4 HMGXB4 10042 NM_001003681 /// NM_005487 /// NM_014250 /// NR_027780 /// XM_006724100 /// XM_006724101 /// XM_006724102 0008333 // endosome to lysosome transport // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0016589 // NURF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 212598_at BE348236 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE348236 /FEA=EST /DB_XREF=gi:9260089 /DB_XREF=est:hw21a12.x1 /CLONE=IMAGE:3183550 /UG=Hs.198135 KIAA0993 protein BE348236 WD repeat and FYVE domain containing 3 WDFY3 23001 NM_014991 /// NM_178583 /// NM_178585 /// XM_005262858 /// XM_006714151 /// XM_006714152 0008152 // metabolic process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0035973 // aggrephagy // inferred from mutant phenotype 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0034274 // Atg12-Atg5-Atg16 complex // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212599_at AK025298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025298.1 /DEF=Homo sapiens cDNA: FLJ21645 fis, clone COL08436. /FEA=mRNA /DB_XREF=gi:10437785 /UG=Hs.32168 KIAA0442 protein AK025298 autism susceptibility candidate 2 AUTS2 26053 NM_001127231 /// NM_001127232 /// NM_015570 /// XM_005250257 /// XM_006715920 212600_s_at AV727381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV727381 /FEA=EST /DB_XREF=gi:10836802 /DB_XREF=est:AV727381 /CLONE=HTCCEF02 /UG=Hs.173554 ubiquinol-cytochrome c reductase core protein II AV727381 ubiquinol-cytochrome c reductase core protein II UQCRC2 7385 NM_003366 0006119 // oxidative phosphorylation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212601_at AB007859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007859.2 /DEF=Homo sapiens mRNA for KIAA0399 protein, partial cds. /FEA=mRNA /GEN=KIAA0399 /PROD=KIAA0399 protein /DB_XREF=gi:6634028 /UG=Hs.100955 KIAA0399 protein AB007859 zinc finger, ZZ-type with EF-hand domain 1 ZZEF1 23140 NM_015113 /// XM_005256560 /// XM_005256561 /// XM_005256562 /// XM_006721485 /// XM_006721486 /// XR_429813 0005509 // calcium ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212602_at AI806395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806395 /FEA=EST /DB_XREF=gi:5392961 /DB_XREF=est:wf27d05.x1 /CLONE=IMAGE:2356809 /UG=Hs.198135 KIAA0993 protein AI806395 WD repeat and FYVE domain containing 3 WDFY3 23001 NM_014991 /// NM_178583 /// NM_178585 /// XM_005262858 /// XM_006714151 /// XM_006714152 0008152 // metabolic process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0035973 // aggrephagy // inferred from mutant phenotype 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0034274 // Atg12-Atg5-Atg16 complex // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212603_at NM_005830 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005830.1 /DEF=Homo sapiens imogen 38 (IMOGN38), mRNA. /FEA=CDS /GEN=IMOGN38 /PROD=imogen 38 /DB_XREF=gi:5031786 /UG=Hs.154655 imogen 38 /FL=gb:NM_005830.1 NM_005830 mitochondrial ribosomal protein S31 MRPS31 10240 NM_005830 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212604_at AI937794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI937794 /FEA=EST /DB_XREF=gi:5676664 /DB_XREF=est:wp82g10.x1 /CLONE=IMAGE:2468322 /UG=Hs.154655 imogen 38 /FL=gb:NM_005830.1 AI937794 mitochondrial ribosomal protein S31 MRPS31 10240 NM_005830 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212605_s_at AK025759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025759.1 /DEF=Homo sapiens cDNA: FLJ22106 fis, clone HEP17675. /FEA=mRNA /DB_XREF=gi:10438374 /UG=Hs.323470 Homo sapiens cDNA: FLJ22106 fis, clone HEP17675 AK025759 nudix (nucleoside diphosphate linked moiety X)-type motif 3 NUDT3 11165 NM_006703 0007267 // cell-cell signaling // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 212606_at AL536319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL536319 /FEA=EST /DB_XREF=gi:12799812 /DB_XREF=est:AL536319 /CLONE=CS0DF015YG13 (3 prime) /UG=Hs.198135 KIAA0993 protein AL536319 WD repeat and FYVE domain containing 3 WDFY3 23001 NM_014991 /// NM_178583 /// NM_178585 /// XM_005262858 /// XM_006714151 /// XM_006714152 0008152 // metabolic process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0035973 // aggrephagy // inferred from mutant phenotype 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0034274 // Atg12-Atg5-Atg16 complex // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212607_at N32526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32526 /FEA=EST /DB_XREF=gi:1152925 /DB_XREF=est:yy11f04.s1 /CLONE=IMAGE:270943 /UG=Hs.300642 serologically defined colon cancer antigen 8 N32526 v-akt murine thymoma viral oncogene homolog 3 AKT3 10000 NM_001206729 /// NM_005465 /// NM_181690 /// XM_005272994 /// XM_005272995 /// XM_005272997 /// XM_006711725 /// XM_006711726 /// XM_006724959 /// XM_006724960 /// XM_006724961 /// XM_006724962 /// XM_006724963 0000002 // mitochondrial genome maintenance // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212608_s_at W85912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W85912 /FEA=EST /DB_XREF=gi:1398341 /DB_XREF=est:zh52b12.s1 /CLONE=IMAGE:415679 /UG=Hs.323470 Homo sapiens cDNA: FLJ22106 fis, clone HEP17675 W85912 nudix (nucleoside diphosphate linked moiety X)-type motif 3 NUDT3 11165 NM_006703 0007267 // cell-cell signaling // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 212609_s_at U79271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79271.1 /DEF=Human clones 23920 and 23921 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710237 /UG=Hs.300642 serologically defined colon cancer antigen 8 U79271 v-akt murine thymoma viral oncogene homolog 3 AKT3 10000 NM_001206729 /// NM_005465 /// NM_181690 /// XM_005272994 /// XM_005272995 /// XM_005272997 /// XM_006711725 /// XM_006711726 /// XM_006724959 /// XM_006724960 /// XM_006724961 /// XM_006724962 /// XM_006724963 0000002 // mitochondrial genome maintenance // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212610_at U79291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79291.1 /DEF=Human clone 23721 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710271 /UG=Hs.83572 Human clone 23721 mRNA sequence U79291 protein tyrosine phosphatase, non-receptor type 11 PTPN11 5781 NM_002834 /// NM_080601 /// XM_006719526 /// XM_006719527 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0036302 // atrioventricular canal development // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051463 // negative regulation of cortisol secretion // inferred from electronic annotation /// 0060125 // negative regulation of growth hormone secretion // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 212611_at AV728526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV728526 /FEA=EST /DB_XREF=gi:10837947 /DB_XREF=est:AV728526 /CLONE=HTCBBD04 /UG=Hs.62264 KIAA0937 protein AV728526 deltex 4, E3 ubiquitin ligase DTX4 23220 NM_015177 /// XM_006718483 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212612_at D31888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D31888.1 /DEF=Human mRNA for KIAA0071 gene, partial cds. /FEA=mRNA /GEN=KIAA0071 /DB_XREF=gi:506340 /UG=Hs.78398 KIAA0071 protein /FL=gb:AF155595.1 gb:NM_015156.1 D31888 REST corepressor 1 RCOR1 23186 NM_015156 /// XM_005267453 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 212613_at AI991252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991252 /FEA=EST /DB_XREF=gi:5838157 /DB_XREF=est:wu41e09.x1 /CLONE=IMAGE:2522632 /UG=Hs.87497 butyrophilin, subfamily 3, member A2 AI991252 butyrophilin, subfamily 3, member A2 BTN3A2 11118 NM_001197246 /// NM_001197247 /// NM_001197248 /// NM_001197249 /// NM_007047 /// XM_005248827 /// XM_005248831 /// XM_005248832 /// XM_006714979 /// XM_006714980 /// XM_006714981 /// XM_006714982 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0072643 // interferon-gamma secretion // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212614_at BG285011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG285011 /FEA=EST /DB_XREF=gi:13036541 /DB_XREF=est:602409278F1 /CLONE=IMAGE:4538275 /UG=Hs.12702 Homo sapiens mRNA; cDNA DKFZp586N012 (from clone DKFZp586N012) BG285011 AT rich interactive domain 5B (MRF1-like) ARID5B 84159 NM_001244638 /// NM_032199 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from sequence or structural similarity /// 0060613 // fat pad development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 212615_at AI742305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742305 /FEA=EST /DB_XREF=gi:5110593 /DB_XREF=est:wg50d02.x1 /CLONE=IMAGE:2368515 /UG=Hs.10351 KIAA0308 protein AI742305 chromodomain helicase DNA binding protein 9 CHD9 80205 NM_025134 /// XM_005256168 /// XM_005256169 /// XM_005256170 /// XM_005256171 /// XM_005256172 /// XM_005256174 /// XM_005256175 /// XM_005256176 /// XM_006721280 /// XM_006721281 /// XM_006721282 /// XM_006721283 /// XR_429731 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 212616_at BF668950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF668950 /FEA=EST /DB_XREF=gi:11942845 /DB_XREF=est:602123069F1 /CLONE=IMAGE:4280153 /UG=Hs.10351 KIAA0308 protein BF668950 chromodomain helicase DNA binding protein 9 CHD9 80205 NM_025134 /// XM_005256168 /// XM_005256169 /// XM_005256170 /// XM_005256171 /// XM_005256172 /// XM_005256174 /// XM_005256175 /// XM_005256176 /// XM_006721280 /// XM_006721281 /// XM_006721282 /// XM_006721283 /// XR_429731 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 212617_at AB002293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002293.1 /DEF=Human mRNA for KIAA0295 gene, partial cds. /FEA=mRNA /GEN=KIAA0295 /DB_XREF=gi:2224530 /UG=Hs.155979 KIAA0295 protein AB002293 zinc finger protein 609 ZNF609 23060 NM_015042 0005634 // nucleus // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 212618_at AA913513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA913513 /FEA=EST /DB_XREF=gi:3052905 /DB_XREF=est:ol37h10.s1 /CLONE=IMAGE:1525699 /UG=Hs.155979 KIAA0295 protein AA913513 zinc finger protein 609 ZNF609 23060 NM_015042 0005634 // nucleus // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 212619_at AW205215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW205215 /FEA=EST /DB_XREF=gi:6504687 /DB_XREF=est:UI-H-BI1-aeo-f-04-0-UI.s1 /CLONE=IMAGE:2720022 /UG=Hs.14912 KIAA0286 protein AW205215 transmembrane protein 194A TMEM194A 23306 NM_001130963 /// NM_015257 /// XM_006719298 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212620_at AW165979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW165979 /FEA=EST /DB_XREF=gi:6397504 /DB_XREF=est:xf43c12.x1 /CLONE=IMAGE:2620822 /UG=Hs.155979 KIAA0295 protein AW165979 zinc finger protein 609 ZNF609 23060 NM_015042 0005634 // nucleus // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 212621_at AB006624 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006624.1 /DEF=Homo sapiens mRNA for KIAA0286 gene, partial cds. /FEA=mRNA /GEN=KIAA0286 /DB_XREF=gi:2564319 /UG=Hs.14912 KIAA0286 protein AB006624 transmembrane protein 194A TMEM194A 23306 NM_001130963 /// NM_015257 /// XM_006719298 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212622_at N64760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64760 /FEA=EST /DB_XREF=gi:1212589 /DB_XREF=est:yz30c06.s1 /CLONE=IMAGE:284554 /UG=Hs.174905 KIAA0033 protein N64760 transmembrane protein 41B TMEM41B 440026 NM_001165030 /// NM_015012 /// NR_028491 0007399 // nervous system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212623_at AU153138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153138 /FEA=EST /DB_XREF=gi:11014659 /DB_XREF=est:AU153138 /CLONE=NT2RP3002507 /UG=Hs.174905 KIAA0033 protein AU153138 transmembrane protein 41B TMEM41B 440026 NM_001165030 /// NM_015012 /// NR_028491 0007399 // nervous system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212624_s_at BF339445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF339445 /FEA=EST /DB_XREF=gi:11285900 /DB_XREF=est:602038795F1 /CLONE=IMAGE:4186582 /UG=Hs.169965 chimerin (chimaerin) 1 BF339445 chimerin 1 CHN1 1123 NM_001025201 /// NM_001206602 /// NM_001822 /// NR_038133 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation 212625_at NM_003765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003765.1 /DEF=Homo sapiens syntaxin 10 (STX10), mRNA. /FEA=CDS /GEN=STX10 /PROD=syntaxin 10 /DB_XREF=gi:4507284 /UG=Hs.43812 syntaxin 10 /FL=gb:AF035531.1 gb:NM_003765.1 NM_003765 syntaxin 10 STX10 8677 NM_001271609 /// NM_001271610 /// NM_001271611 /// NM_003765 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006906 // vesicle fusion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0031201 // SNARE complex // not recorded 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 212626_x_at AA664258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA664258 /FEA=EST /DB_XREF=gi:2618249 /DB_XREF=est:ac08a08.s1 /CLONE=IMAGE:855830 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) AA664258 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212627_s_at AL581473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL581473 /FEA=EST /DB_XREF=gi:12948508 /DB_XREF=est:AL581473 /CLONE=CS0DG004YK09 (3 prime) /UG=Hs.182877 KIAA0116 protein AL581473 exosome component 7 EXOSC7 23016 NM_015004 /// NR_023353 /// XM_006713035 /// XR_245104 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0006401 // RNA catabolic process // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 212628_at BG292065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG292065 /FEA=EST /DB_XREF=gi:13050507 /DB_XREF=est:602386350F1 /CLONE=IMAGE:4515036 /UG=Hs.69171 protein kinase C-like 2 BG292065 protein kinase N2 PKN2 5586 NM_006256 /// XM_005271031 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010631 // epithelial cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 2000145 // regulation of cell motility // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212629_s_at AI633689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633689 /FEA=EST /DB_XREF=gi:4685019 /DB_XREF=est:th71d03.x1 /CLONE=IMAGE:2124101 /UG=Hs.69171 protein kinase C-like 2 AI633689 protein kinase N2 PKN2 5586 NM_006256 /// XM_005271031 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010631 // epithelial cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 2000145 // regulation of cell motility // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212630_at AF055006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055006.1 /DEF=Homo sapiens clone 24666 sec6 homolog mRNA, partial cds. /FEA=mRNA /PROD=sec6 homolog /DB_XREF=gi:3005726 /UG=Hs.8088 similar to S. cerevisiae Sec6p and R. norvegicus rsec6 AF055006 exocyst complex component 3 EXOC3 11336 NM_007277 /// XM_005248238 /// XM_005248239 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 212631_at AI566082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI566082 /FEA=EST /DB_XREF=gi:4524534 /DB_XREF=est:tn53b12.x1 /CLONE=IMAGE:2172095 /UG=Hs.8906 Homo sapiens clone 24889 mRNA sequence AI566082 syntaxin 7 STX7 8417 NM_003569 0006886 // intracellular protein transport // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0000149 // SNARE binding // inferred from direct assay /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 212632_at N32035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32035 /FEA=EST /DB_XREF=gi:1152434 /DB_XREF=est:yw96e08.s1 /CLONE=IMAGE:260102 /UG=Hs.8906 Homo sapiens clone 24889 mRNA sequence N32035 syntaxin 7 STX7 8417 NM_003569 0006886 // intracellular protein transport // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0000149 // SNARE binding // inferred from direct assay /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 212633_at AL132776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL132776 /DEF=Human DNA sequence from clone RP3-393D12 on chromosome 6q16.1-16.3. Contains the 3 end of the gene KIAA0776, the gene for a novel LIM domain protein, ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:6706246 /UG=Hs.5460 KIAA0776 protein AL132776 UFM1-specific ligase 1 UFL1 23376 NM_015323 0001649 // osteoblast differentiation // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0071569 // protein ufmylation // inferred from direct assay /// 0071569 // protein ufmylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0071568 // UFM1 conjugating enzyme activity // inferred from direct assay 212634_at AW298092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW298092 /FEA=EST /DB_XREF=gi:6704728 /DB_XREF=est:UI-H-BW0-ajs-b-03-0-UI.s1 /CLONE=IMAGE:2732860 /UG=Hs.5460 KIAA0776 protein AW298092 UFM1-specific ligase 1 UFL1 23376 NM_015323 0001649 // osteoblast differentiation // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0071569 // protein ufmylation // inferred from direct assay /// 0071569 // protein ufmylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0071568 // UFM1 conjugating enzyme activity // inferred from direct assay 212635_at AW161626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW161626 /FEA=EST /DB_XREF=gi:6300659 /DB_XREF=est:au68b11.x1 /CLONE=IMAGE:2781405 /UG=Hs.21739 Homo sapiens mRNA; cDNA DKFZp586I1518 (from clone DKFZp586I1518) AW161626 transportin 1 TNPO1 3842 NM_002270 /// NM_153188 /// XM_005248500 /// XM_005248501 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212636_at AL031781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031781 /DEF=Human DNA sequence from clone 51J12 on chromosome 6q26-27. Contains the 3 part of the alternatively spliced gene for the human orthologs of mouse QKI-7 and QKI-7B (KH Domain RNA Binding proteins) and zebrafish ZKQ-1 (Quaking protein homolog). Con... /FEA=mRNA_2 /DB_XREF=gi:4038570 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142417.1 AL031781 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212637_s_at AU155187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU155187 /FEA=EST /DB_XREF=gi:11016708 /DB_XREF=est:AU155187 /CLONE=OVARC1001219 /UG=Hs.324275 Homo sapiens mRNA; cDNA DKFZp434D2111 (from clone DKFZp434D2111) AU155187 WW domain containing E3 ubiquitin protein ligase 1 WWP1 11059 NM_007013 /// XM_005250760 /// XM_005250761 0007165 // signal transduction // non-traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046718 // viral entry into host cell // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 212638_s_at BF131791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF131791 /FEA=EST /DB_XREF=gi:10970831 /DB_XREF=est:601820701F1 /CLONE=IMAGE:4052256 /UG=Hs.324275 Homo sapiens mRNA; cDNA DKFZp434D2111 (from clone DKFZp434D2111) BF131791 WW domain containing E3 ubiquitin protein ligase 1 WWP1 11059 NM_007013 /// XM_005250760 /// XM_005250761 0007165 // signal transduction // non-traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046718 // viral entry into host cell // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 212639_x_at AL581768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL581768 /FEA=EST /DB_XREF=gi:12949093 /DB_XREF=est:AL581768 /CLONE=CS0DG007YA06 (3 prime) /UG=Hs.272897 Tubulin, alpha, brain-specific AL581768 tubulin, alpha 1b TUBA1B 10376 NM_006082 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 212640_at AV712602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV712602 /FEA=EST /DB_XREF=gi:10731908 /DB_XREF=est:AV712602 /CLONE=DCAACD04 /UG=Hs.5957 Homo sapiens clone 24416 mRNA sequence AV712602 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b PTPLB 201562 NM_198402 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation 212641_at AL023584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023584 /DEF=Human DNA sequence from clone 67K17 on chromosome 6q24.1-24.3. Contains the HIVEP2 (Schnurri-2) gene for HIV type 1 Enhancer-binding Protein 2, and a possible pseudogene in an intron of this gene. Contains STSs and GSSs and an AAAT repeat polymorp... /FEA=mRNA /DB_XREF=gi:3790154 /UG=Hs.75063 human immunodeficiency virus type I enhancer-binding protein 2 /FL=gb:NM_006734.1 AL023584 human immunodeficiency virus type I enhancer binding protein 2 HIVEP2 3097 NM_006734 /// XM_005266957 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212642_s_at AL023584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023584 /DEF=Human DNA sequence from clone 67K17 on chromosome 6q24.1-24.3. Contains the HIVEP2 (Schnurri-2) gene for HIV type 1 Enhancer-binding Protein 2, and a possible pseudogene in an intron of this gene. Contains STSs and GSSs and an AAAT repeat polymorp... /FEA=mRNA /DB_XREF=gi:3790154 /UG=Hs.75063 human immunodeficiency virus type I enhancer-binding protein 2 /FL=gb:NM_006734.1 AL023584 human immunodeficiency virus type I enhancer binding protein 2 HIVEP2 3097 NM_006734 /// XM_005266957 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212643_at AI671747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI671747 /FEA=EST /DB_XREF=gi:4851478 /DB_XREF=est:wa05e06.x1 /CLONE=IMAGE:2297218 /UG=Hs.81360 Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence AI671747 mitogen-activated protein kinase 1 interacting protein 1-like MAPK1IP1L 93487 NM_144578 212644_s_at AI671747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI671747 /FEA=EST /DB_XREF=gi:4851478 /DB_XREF=est:wa05e06.x1 /CLONE=IMAGE:2297218 /UG=Hs.81360 Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence AI671747 mitogen-activated protein kinase 1 interacting protein 1-like MAPK1IP1L 93487 NM_144578 212645_x_at AL566299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566299 /FEA=EST /DB_XREF=gi:12918529 /DB_XREF=est:AL566299 /CLONE=CS0DF015YB11 (3 prime) /UG=Hs.80426 brain and reproductive organ-expressed (TNFRSF1A modulator) AL566299 brain and reproductive organ-expressed (TNFRSF1A modulator) BRE 9577 NM_001261840 /// NM_004899 /// NM_199191 /// NM_199192 /// NM_199193 /// NM_199194 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype 0000152 // nuclear ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 212646_at D42043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D42043.1 /DEF=Human mRNA for KIAA0084 gene, partial cds. /FEA=mRNA /GEN=KIAA0084 /DB_XREF=gi:577298 /UG=Hs.79123 KIAA0084 protein D42043 raftlin, lipid raft linker 1 RFTN1 23180 NM_015150 /// XM_005264985 /// XM_005264986 /// XM_005264987 /// XM_005264988 /// XM_006713069 /// XM_006713070 /// XM_006713071 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from sequence or structural similarity /// 0032596 // protein transport into membrane raft // inferred from sequence or structural similarity /// 0032620 // interleukin-17 production // inferred from sequence or structural similarity /// 0033227 // dsRNA transport // inferred from mutant phenotype /// 0034138 // toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0040007 // growth // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 1903044 // protein localization to membrane raft // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay 212647_at NM_006270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006270.1 /DEF=Homo sapiens related RAS viral (r-ras) oncogene homolog (RRAS), mRNA. /FEA=CDS /GEN=RRAS /PROD=related RAS viral (r-ras) oncogene homolog /DB_XREF=gi:5454027 /UG=Hs.9651 related RAS viral (r-ras) oncogene homolog /FL=gb:NM_006270.1 NM_006270 related RAS viral (r-ras) oncogene homolog RRAS 6237 NM_006270 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 212648_at AL079292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079292.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 48814. /FEA=mRNA /PROD=hypothetical protein, similar to (AC007017)putative RNA helicase A Arabidopsis thaliana /DB_XREF=gi:5102732 /UG=Hs.95665 hypothetical protein AL079292 DEAH (Asp-Glu-Ala-His) box polypeptide 29 DHX29 54505 NM_019030 /// XM_005248544 /// XM_006714653 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212649_at AL079292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079292.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 48814. /FEA=mRNA /PROD=hypothetical protein, similar to (AC007017)putative RNA helicase A Arabidopsis thaliana /DB_XREF=gi:5102732 /UG=Hs.95665 hypothetical protein AL079292 212650_at BF116032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF116032 /FEA=EST /DB_XREF=gi:10985508 /DB_XREF=est:7n76e11.x1 /CLONE=IMAGE:3570548 /UG=Hs.16218 KIAA0903 protein BF116032 EH domain binding protein 1 EHBP1 23301 NM_001142614 /// NM_001142615 /// NM_001142616 /// NM_015252 /// XM_005264225 /// XM_005264226 /// XM_005264227 /// XM_005264228 /// XM_006711971 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212651_at AB018283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018283.2 /DEF=Homo sapiens mRNA for KIAA0740 protein, partial cds. /FEA=mRNA /GEN=KIAA0740 /PROD=KIAA0740 protein /DB_XREF=gi:6705974 /UG=Hs.15099 KIAA0740 gene product AB018283 Rho-related BTB domain containing 1 RHOBTB1 9886 NM_001242359 /// NM_014836 /// NR_024554 /// NR_024555 /// XM_006718084 /// XM_006718085 /// XM_006718086 /// XM_006718087 /// XM_006718088 /// XM_006718089 /// XR_428729 /// XR_428730 /// XR_428731 /// XR_428732 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 212652_s_at AA524345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524345 /FEA=EST /DB_XREF=gi:2265273 /DB_XREF=est:ng43a06.s1 /CLONE=IMAGE:937522 /UG=Hs.267812 sorting nexin 4 AA524345 sorting nexin 4 SNX4 8723 NM_003794 /// NR_073435 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0032456 // endocytic recycling // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from mutant phenotype 212653_s_at AB020710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020710.1 /DEF=Homo sapiens mRNA for KIAA0903 protein, partial cds. /FEA=mRNA /GEN=KIAA0903 /PROD=KIAA0903 protein /DB_XREF=gi:4240294 /UG=Hs.16218 KIAA0903 protein AB020710 EH domain binding protein 1 EHBP1 23301 NM_001142614 /// NM_001142615 /// NM_001142616 /// NM_015252 /// XM_005264225 /// XM_005264226 /// XM_005264227 /// XM_005264228 /// XM_006711971 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212654_at AL566786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566786 /FEA=EST /DB_XREF=gi:12919494 /DB_XREF=est:AL566786 /CLONE=CS0DF025YL12 (3 prime) /UG=Hs.300772 tropomyosin 2 (beta) AL566786 tropomyosin 2 (beta) TPM2 7169 NM_001145822 /// NM_003289 /// NM_213674 /// XM_005251566 /// XM_005251567 /// XM_005251568 /// XM_005251569 /// XM_005251570 /// XM_005251571 /// XM_005251572 0006936 // muscle contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0043462 // regulation of ATPase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005862 // muscle thin filament tropomyosin // traceable author statement 0003779 // actin binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement 212655_at AB011151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011151.1 /DEF=Homo sapiens mRNA for KIAA0579 protein, partial cds. /FEA=mRNA /GEN=KIAA0579 /PROD=KIAA0579 protein /DB_XREF=gi:3043681 /UG=Hs.81505 KIAA0579 protein AB011151 zinc finger, CCHC domain containing 14 ZCCHC14 23174 NM_015144 /// XM_005255858 /// XR_243401 0007154 // cell communication // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212656_at AF110399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF110399.1 /DEF=Homo sapiens elongation factor Ts mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=CDS /PROD=elongation factor Ts /DB_XREF=gi:4416085 /UG=Hs.3273 Ts translation elongation factor, mitochondrial /FL=gb:AF110399.1 AF110399 Ts translation elongation factor, mitochondrial TSFM 10102 NM_001172695 /// NM_001172696 /// NM_001172697 /// NM_005726 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212657_s_at U65590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U65590 /DEF=Homo sapiens IL-1 receptor antagonist IL-1Ra (IL-1RN) gene, alternatively spliced forms, complete cds /FEA=mRNA_2 /DB_XREF=gi:2707374 /UG=Hs.81134 interleukin 1 receptor antagonist U65590 interleukin 1 receptor antagonist IL1RN 3557 NM_000577 /// NM_173841 /// NM_173842 /// NM_173843 /// XM_005263661 /// XM_006712497 0001660 // fever generation // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005150 // interleukin-1, Type I receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // inferred from physical interaction /// 0005152 // interleukin-1 receptor antagonist activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // traceable author statement /// 0045352 // interleukin-1 Type I receptor antagonist activity // inferred from direct assay /// 0045353 // interleukin-1 Type II receptor antagonist activity // inferred from direct assay 212658_at N66633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N66633 /FEA=EST /DB_XREF=gi:1218758 /DB_XREF=est:yy70f02.s1 /CLONE=IMAGE:278907 /UG=Hs.79299 lipoma HMGIC fusion partner-like 2 N66633 lipoma HMGIC fusion partner-like 2 LHFPL2 10184 NM_005779 /// XM_006714515 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212659_s_at AW083357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW083357 /FEA=EST /DB_XREF=gi:6038509 /DB_XREF=est:xc08g03.x1 /CLONE=IMAGE:2583700 /UG=Hs.81134 interleukin 1 receptor antagonist AW083357 interleukin 1 receptor antagonist IL1RN 3557 NM_000577 /// NM_173841 /// NM_173842 /// NM_173843 /// XM_005263661 /// XM_006712497 0001660 // fever generation // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005150 // interleukin-1, Type I receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // inferred from physical interaction /// 0005152 // interleukin-1 receptor antagonist activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // traceable author statement /// 0045352 // interleukin-1 Type I receptor antagonist activity // inferred from direct assay /// 0045353 // interleukin-1 Type II receptor antagonist activity // inferred from direct assay 212660_at AI735639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI735639 /FEA=EST /DB_XREF=gi:5057163 /DB_XREF=est:at18h12.x1 /CLONE=IMAGE:2355527 /UG=Hs.9729 KIAA0239 protein AI735639 jade family PHD finger 2 JADE2 23338 NM_001289984 /// NM_001289985 /// NM_015288 /// XM_005271942 /// XM_005271943 /// XM_005271944 /// XM_005271945 /// XM_005271946 /// XM_005271947 /// XM_005271948 /// XM_005271949 /// XM_005271950 /// XM_005271951 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212661_x_at BE731738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE731738 /FEA=EST /DB_XREF=gi:10145730 /DB_XREF=est:601568154F1 /CLONE=IMAGE:3842844 /UG=Hs.182937 peptidylprolyl isomerase A (cyclophilin A) BE731738 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 212662_at BE615277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE615277 /FEA=EST /DB_XREF=gi:9896876 /DB_XREF=est:601280637F1 /CLONE=IMAGE:3622736 /UG=Hs.171844 Homo sapiens cDNA: FLJ22296 fis, clone HRC04468 BE615277 poliovirus receptor PVR 5817 NM_001135768 /// NM_001135769 /// NM_001135770 /// NM_006505 /// XM_005259120 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 212663_at AB014574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014574.1 /DEF=Homo sapiens mRNA for KIAA0674 protein, partial cds. /FEA=mRNA /GEN=KIAA0674 /PROD=KIAA0674 protein /DB_XREF=gi:3327161 /UG=Hs.14799 KIAA0674 protein AB014574 FK506 binding protein 15, 133kDa FKBP15 23307 NM_015258 /// XM_006717018 /// XM_006717019 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 212664_at AL567012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567012 /FEA=EST /DB_XREF=gi:12919960 /DB_XREF=est:AL567012 /CLONE=CS0DF028YP03 (3 prime) /UG=Hs.110837 tubulin, beta, 5 /FL=gb:NM_006087.1 AL567012 tubulin, beta 4A class IVa TUBB4A 10382 NM_001289123 /// NM_001289127 /// NM_001289129 /// NM_001289130 /// NM_001289131 /// NM_006087 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0033269 // internode region of axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 212665_at AL556438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL556438 /FEA=EST /DB_XREF=gi:12899113 /DB_XREF=est:AL556438 /CLONE=CS0DK004YI18 (3 prime) /UG=Hs.12813 DKFZP434J214 protein AL556438 TCDD-inducible poly(ADP-ribose) polymerase TIPARP 25976 NM_001184717 /// NM_001184718 /// NM_015508 0001570 // vasculogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0044236 // multicellular organismal metabolic process // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0035326 // enhancer binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212666_at AB046845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046845.1 /DEF=Homo sapiens mRNA for KIAA1625 protein, partial cds. /FEA=mRNA /GEN=KIAA1625 /PROD=KIAA1625 protein /DB_XREF=gi:10047326 /UG=Hs.119120 E3 ubiquitin ligase SMURF1 AB046845 SMAD specific E3 ubiquitin protein ligase 1 SMURF1 57154 NM_001199847 /// NM_020429 /// NM_181349 /// XM_005250507 /// XM_006716061 /// XM_006716062 0000209 // protein polyubiquitination // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007398 // ectoderm development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0048185 // activin binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 212667_at AL575922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL575922 /FEA=EST /DB_XREF=gi:12937561 /DB_XREF=est:AL575922 /CLONE=CS0DI067YN03 (3 prime) /UG=Hs.111779 secreted protein, acidic, cysteine-rich (osteonectin) AL575922 secreted protein, acidic, cysteine-rich (osteonectin) SPARC 6678 NM_003118 0001503 // ossification // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009629 // response to gravity // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0071682 // endocytic vesicle lumen // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 212668_at AI654869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI654869 /FEA=EST /DB_XREF=gi:4738848 /DB_XREF=est:wb65d02.x1 /CLONE=IMAGE:2310531 /UG=Hs.119120 E3 ubiquitin ligase SMURF1 AI654869 SMAD specific E3 ubiquitin protein ligase 1 SMURF1 57154 NM_001199847 /// NM_020429 /// NM_181349 /// XM_005250507 /// XM_006716061 /// XM_006716062 0000209 // protein polyubiquitination // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007398 // ectoderm development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0048185 // activin binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 212669_at AI093569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI093569 /FEA=EST /DB_XREF=gi:3432545 /DB_XREF=est:qb15f08.x1 /CLONE=IMAGE:1696359 /UG=Hs.250857 calciumcalmodulin-dependent protein kinase (CaM kinase) II gamma AI093569 calcium/calmodulin-dependent protein kinase II gamma CAMK2G 818 NM_001204492 /// NM_001222 /// NM_172169 /// NM_172170 /// NM_172171 /// NM_172172 /// NM_172173 /// XM_005270195 /// XM_005270197 /// XM_005270198 /// XM_005270199 /// XM_005270200 /// XM_005270201 /// XM_005270202 /// XM_005270203 /// XM_005270205 /// XM_006717993 /// XM_006717994 /// XM_006717995 /// XM_006717996 /// XM_006717997 /// XM_006717998 /// XM_006717999 /// XM_006718000 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030073 // insulin secretion // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 1901897 // regulation of relaxation of cardiac muscle // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212670_at AA479278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA479278 /FEA=EST /DB_XREF=gi:2207834 /DB_XREF=est:zv21b07.s1 /CLONE=IMAGE:754261 /UG=Hs.9295 elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) /FL=gb:M36860.1 AA479278 elastin ELN 2006 NM_000501 /// NM_001081752 /// NM_001081753 /// NM_001081754 /// NM_001081755 /// NM_001278912 /// NM_001278913 /// NM_001278914 /// NM_001278915 /// NM_001278916 /// NM_001278917 /// NM_001278918 /// NM_001278939 /// XM_005250187 /// XM_005250188 /// XM_006715874 /// XM_006715875 /// XM_006715876 /// XM_006715877 /// XM_006715878 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0071953 // elastic fiber // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 212671_s_at BG397856 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG397856 /FEA=EST /DB_XREF=gi:13291304 /DB_XREF=est:602438950F1 /CLONE=IMAGE:4564956 /UG=Hs.198253 major histocompatibility complex, class II, DQ alpha 1 BG397856 major histocompatibility complex, class II, DQ alpha 1 /// major histocompatibility complex, class II, DQ alpha 2 /// HLA class II histocompatibility antigen, DQ alpha 1 chain-like HLA-DQA1 /// HLA-DQA2 /// LOC100509457 3117 /// 3118 /// 100509457 NM_002122 /// NM_020056 /// XM_003120269 /// XM_003846468 /// XM_005274953 /// XM_005275108 /// XM_005275333 /// XM_005275542 /// XM_005275544 /// XM_005276080 /// XM_006715079 /// XM_006725484 /// XM_006725999 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 212672_at U82828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82828 /DEF=Homo sapiens ataxia telangiectasia (ATM) gene, complete cds /FEA=mRNA_1 /DB_XREF=gi:2304970 /UG=Hs.194382 ataxia telangiectasia mutated (includes complementation groups A, C and D) U82828 ATM serine/threonine kinase ATM 472 NM_000051 /// NM_138292 /// NM_138293 /// XM_005271561 /// XM_005271562 /// XM_005271564 /// XM_006718843 /// XM_006718844 /// XM_006718845 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0002331 // pre-B cell allelic exclusion // inferred from sequence or structural similarity /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007292 // female gamete generation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048599 // oocyte development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0072434 // signal transduction involved in mitotic G2 DNA damage checkpoint // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0035174 // histone serine kinase activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 212673_at D42084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D42084.1 /DEF=Human mRNA for KIAA0094 gene, partial cds. /FEA=mRNA /GEN=KIAA0094 /DB_XREF=gi:577314 /UG=Hs.82007 KIAA0094 protein D42084 methionyl aminopeptidase 1 METAP1 23173 NM_015143 /// XM_005262867 /// XM_005262868 0006417 // regulation of translation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018206 // peptidyl-methionine modification // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031365 // N-terminal protein amino acid modification // traceable author statement /// 0070084 // protein initiator methionine removal // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0022626 // cytosolic ribosome // inferred from electronic annotation 0004177 // aminopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from electronic annotation 212674_s_at AK002076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002076.1 /DEF=Homo sapiens cDNA FLJ11214 fis, clone PLACE1007990. /FEA=mRNA /DB_XREF=gi:7023738 /UG=Hs.281616 Homo sapiens cDNA FLJ11214 fis, clone PLACE1007990 AK002076 DEAH (Asp-Glu-Ala-His) box helicase 30 DHX30 22907 NM_014966 /// NM_138614 /// NM_138615 /// NR_075079 /// XM_006713032 /// XM_006713033 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212675_s_at AB011154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011154.1 /DEF=Homo sapiens mRNA for KIAA0582 protein, partial cds. /FEA=mRNA /GEN=KIAA0582 /PROD=KIAA0582 protein /DB_XREF=gi:3043687 /UG=Hs.79507 KIAA0582 protein AB011154 centrosomal protein 68kDa CEP68 23177 NM_015147 /// XM_005264218 /// XM_005264219 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 212676_at AW293356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW293356 /FEA=EST /DB_XREF=gi:6699992 /DB_XREF=est:UI-H-BI2-ahl-c-11-0-UI.s1 /CLONE=IMAGE:2727165 /UG=Hs.58220 Homo sapiens cDNA: FLJ23005 fis, clone LNG00396, highly similar to AF055023 Homo sapiens clone 24723 mRNA sequence AW293356 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 212677_s_at BG530481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG530481 /FEA=EST /DB_XREF=gi:13522018 /DB_XREF=est:602559046F1 /CLONE=IMAGE:4697218 /UG=Hs.79507 KIAA0582 protein BG530481 centrosomal protein 68kDa CEP68 23177 NM_015147 /// XM_005264218 /// XM_005264219 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 212678_at AW054826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW054826 /FEA=EST /DB_XREF=gi:5920529 /DB_XREF=est:ws60c12.x1 /CLONE=IMAGE:2501590 /UG=Hs.58220 Homo sapiens cDNA: FLJ23005 fis, clone LNG00396, highly similar to AF055023 Homo sapiens clone 24723 mRNA sequence AW054826 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 212679_at AK026529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026529.1 /DEF=Homo sapiens cDNA: FLJ22876 fis, clone KAT02954, highly similar to AF056183 Homo sapiens WS beta-transducin repeats protein mRNA. /FEA=mRNA /DB_XREF=gi:10439407 /UG=Hs.52515 transducin (beta)-like 2 AK026529 transducin (beta)-like 2 TBL2 26608 NM_012453 /// NM_032988 /// XM_006715923 0044822 // poly(A) RNA binding // inferred from direct assay 212680_x_at BE305165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE305165 /FEA=EST /DB_XREF=gi:9177184 /DB_XREF=est:601186685T1 /CLONE=IMAGE:2959580 /UG=Hs.100623 phospholipase C, beta 3, neighbor pseudogene BE305165 protein phosphatase 1, regulatory (inhibitor) subunit 14B PPP1R14B 26472 NM_138689 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // inferred from electronic annotation /// 0019212 // phosphatase inhibitor activity // inferred from electronic annotation 212681_at AI770004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI770004 /FEA=EST /DB_XREF=gi:5236513 /DB_XREF=est:wh66d06.x1 /CLONE=IMAGE:2385707 /UG=Hs.103839 erythrocyte membrane protein band 4.1-like 3 AI770004 erythrocyte membrane protein band 4.1-like 3 EPB41L3 23136 NM_001281533 /// NM_001281534 /// NM_001281535 /// NM_012307 /// XM_005258085 /// XM_005258086 /// XM_005258087 /// XM_005258088 /// XM_005258089 /// XM_005258090 /// XM_005258091 /// XM_006722301 /// XM_006722302 /// XM_006722303 /// XM_006722304 /// XM_006722305 /// XM_006722306 /// XM_006722307 /// XM_006722308 /// XM_006722309 /// XM_006722310 /// XM_006722311 /// XM_006722312 /// XM_006722313 /// XM_006722314 /// XM_006722315 /// XM_006722316 0002175 // protein localization to paranode region of axon // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0030865 // cortical cytoskeleton organization // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 212682_s_at AI081535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI081535 /FEA=EST /DB_XREF=gi:3418327 /DB_XREF=est:on04g03.x1 /CLONE=IMAGE:1555732 /UG=Hs.150540 Homo sapiens, clone IMAGE:3954961, mRNA, partial cds AI081535 lipase maturation factor 2 LMF2 91289 NM_033200 /// XM_005261955 /// XM_006724426 /// XM_006724427 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212683_at AL526243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL526243 /FEA=EST /DB_XREF=gi:12789736 /DB_XREF=est:AL526243 /CLONE=CS0DC016YF06 (5 prime) /UG=Hs.158286 KIAA0446 gene product AL526243 solute carrier family 25, member 44 SLC25A44 9673 NM_001135672 /// NM_001286184 /// NM_014655 /// NR_104408 /// NR_104411 /// NR_104412 /// XM_006711657 /// XM_006711658 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212684_at AI752257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI752257 /FEA=EST /DB_XREF=gi:5130521 /DB_XREF=est:cn14f02.x1 /CLONE=NHTBC_cn14f02 (random) /UG=Hs.155470 zinc finger protein 38 (KOX 25) AI752257 zinc finger protein 3 ZNF3 7551 NM_001278284 /// NM_001278287 /// NM_001278290 /// NM_001278291 /// NM_001278292 /// NM_017715 /// NM_032924 /// XM_006716110 /// XM_006716111 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045321 // leukocyte activation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212685_s_at AI608789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI608789 /FEA=EST /DB_XREF=gi:4617956 /DB_XREF=est:tw94g12.x1 /CLONE=IMAGE:2267398 /UG=Hs.52515 transducin (beta)-like 2 AI608789 transducin (beta)-like 2 TBL2 26608 NM_012453 /// NM_032988 /// XM_006715923 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212686_at AB032983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032983.1 /DEF=Homo sapiens mRNA for KIAA1157 protein, partial cds. /FEA=mRNA /GEN=KIAA1157 /PROD=KIAA1157 protein /DB_XREF=gi:6330128 /UG=Hs.21894 KIAA1157 protein AB032983 protein phosphatase, Mg2+/Mn2+ dependent, 1H PPM1H 57460 NM_020700 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212687_at AL110164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110164.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I0324 (from clone DKFZp586I0324). /FEA=mRNA /DB_XREF=gi:5817069 /UG=Hs.193700 Homo sapiens mRNA; cDNA DKFZp586I0324 (from clone DKFZp586I0324) AL110164 LIM and senescent cell antigen-like domains 1 /// LIM and senescent cell antigen-like domains 3 /// LIM and senescent cell antigen-like domains 3-like LIMS1 /// LIMS3 /// LIMS3L 3987 /// 96626 /// 100288695 NM_001193482 /// NM_001193483 /// NM_001193484 /// NM_001193485 /// NM_001193488 /// NM_001205288 /// NM_004987 /// NM_033514 /// NR_027467 /// NR_038099 /// XM_005263563 /// XM_005263946 /// XM_005263947 /// XM_005263948 /// XM_005263949 /// XM_005263950 /// XM_005263951 /// XM_006712167 /// XM_006712524 /// XR_244813 0007569 // cell aging // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212688_at BC003393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003393.1 /DEF=Homo sapiens, clone IMAGE:3447173, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3447173) /DB_XREF=gi:13097275 /UG=Hs.239818 phosphoinositide-3-kinase, catalytic, beta polypeptide /FL=gb:NM_006219.1 BC003393 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta PIK3CB 5291 NM_001256045 /// NM_006219 /// XM_005247530 /// XM_005247531 /// XM_005247532 /// XM_006713659 0000187 // activation of MAPK activity // traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010508 // positive regulation of autophagy // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0070527 // platelet aggregation // traceable author statement /// 2000369 // regulation of clathrin-mediated endocytosis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 212689_s_at AA524505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524505 /FEA=EST /DB_XREF=gi:2265433 /DB_XREF=est:ng43g12.s1 /CLONE=IMAGE:937606 /UG=Hs.321707 KIAA0742 protein AA524505 lysine (K)-specific demethylase 3A KDM3A 55818 NM_001146688 /// NM_018433 /// XM_006712051 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007290 // spermatid nucleus elongation // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0036123 // histone H3-K9 dimethylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046293 // formaldehyde biosynthetic process // inferred from direct assay /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation 212690_at AB018268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018268.1 /DEF=Homo sapiens mRNA for KIAA0725 protein, partial cds. /FEA=mRNA /GEN=KIAA0725 /PROD=KIAA0725 protein /DB_XREF=gi:3882170 /UG=Hs.26450 KIAA0725 protein AB018268 DDHD domain containing 2 DDHD2 23259 NM_001164232 /// NM_001164234 /// NM_015214 /// XM_005273454 /// XM_005273455 /// XM_005273456 /// XM_005273457 /// XR_247123 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212691_at AW131863 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW131863 /FEA=EST /DB_XREF=gi:6133470 /DB_XREF=est:xf35f02.x1 /CLONE=IMAGE:2620059 /UG=Hs.30002 SH3-containing protein SH3GLB2 AW131863 nucleoporin 188kDa NUP188 23511 NM_015354 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation 212692_s_at W60686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W60686 /FEA=EST /DB_XREF=gi:1367445 /DB_XREF=est:zd26a07.s1 /CLONE=IMAGE:341748 /UG=Hs.62354 cell division cycle 4-like W60686 LPS-responsive vesicle trafficking, beach and anchor containing LRBA 987 NM_001199282 /// NM_006726 /// XM_005263372 /// XM_005263373 /// XM_005263374 /// XM_005263375 /// XM_005263376 /// XM_005263377 /// XM_006714429 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212693_at BE670928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE670928 /FEA=EST /DB_XREF=gi:10031469 /DB_XREF=est:7e43b11.x1 /CLONE=IMAGE:3285213 /UG=Hs.76730 KIAA0301 protein BE670928 MDN1, midasin homolog (yeast) MDN1 23195 NM_014611 /// XM_005248699 /// XM_005248700 /// XM_006715404 /// XM_006715405 /// XR_427966 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006461 // protein complex assembly // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // non-traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 212694_s_at NM_000532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000532.1 /DEF=Homo sapiens propionyl Coenzyme A carboxylase, beta polypeptide (PCCB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=CDS /GEN=PCCB /PROD=propionyl Coenzyme A carboxylase, betapolypeptide /DB_XREF=gi:4557043 /UG=Hs.63788 propionyl Coenzyme A carboxylase, beta polypeptide /FL=gb:NM_000532.1 NM_000532 propionyl CoA carboxylase, beta polypeptide PCCB 5096 NM_000532 /// NM_001178014 /// XM_005247508 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0009317 // acetyl-CoA carboxylase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from electronic annotation /// 0004658 // propionyl-CoA carboxylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 212695_at AB014558 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014558.1 /DEF=Homo sapiens mRNA for KIAA0658 protein, partial cds. /FEA=mRNA /GEN=KIAA0658 /PROD=KIAA0658 protein /DB_XREF=gi:3327129 /UG=Hs.7278 cryptochrome 2 (photolyase-like) AB014558 cryptochrome circadian clock 2 CRY2 1408 NM_001127457 /// NM_021117 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000719 // photoreactive repair // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0009785 // blue light signaling pathway // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 2000118 // regulation of sodium-dependent phosphate transport // inferred from direct assay /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003904 // deoxyribodipyrimidine photo-lyase activity // inferred from direct assay /// 0003913 // DNA photolyase activity // inferred from electronic annotation /// 0003914 // DNA (6-4) photolyase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0009881 // photoreceptor activity // inferred from electronic annotation /// 0009882 // blue light photoreceptor activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0071949 // FAD binding // inferred from sequence or structural similarity 212696_s_at BF968633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF968633 /FEA=EST /DB_XREF=gi:12335848 /DB_XREF=est:602271068F1 /CLONE=IMAGE:4359209 /UG=Hs.66394 ring finger protein 4 BF968633 ring finger protein 4 RNF4 6047 NM_001185009 /// NM_001185010 /// NM_002938 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity /// 0070936 // protein K48-linked ubiquitination // inferred from sequence or structural similarity /// 0070979 // protein K11-linked ubiquitination // inferred from sequence or structural similarity /// 0085020 // protein K6-linked ubiquitination // inferred from sequence or structural similarity /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from sequence or structural similarity /// 0032184 // SUMO polymer binding // inferred from sequence or structural similarity /// 0033142 // progesterone receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 212697_at AL515874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515874 /FEA=EST /DB_XREF=gi:12779367 /DB_XREF=est:AL515874 /CLONE=CS0DA001YF06 (3 prime) /UG=Hs.83086 Homo sapiens GT212 mRNA AL515874 family with sequence similarity 134, member C FAM134C 162427 NM_178126 /// NR_026697 /// XM_006721729 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212698_s_at BF966021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF966021 /FEA=EST /DB_XREF=gi:12333236 /DB_XREF=est:602277319F1 /CLONE=IMAGE:4364933 /UG=Hs.79844 DKFZP564M1416 protein BF966021 septin 10 SEPT10 151011 NM_144710 /// NM_178584 /// NR_047585 /// XM_006712317 /// XM_006712318 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 212699_at BE222801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222801 /FEA=EST /DB_XREF=gi:8910119 /DB_XREF=est:hu53e01.x1 /CLONE=IMAGE:3173784 /UG=Hs.7934 Kruppel-like factor 4 (gut) BE222801 secretory carrier membrane protein 5 SCAMP5 192683 NM_001178111 /// NM_001178112 /// NM_138967 /// NR_033660 /// XM_006720420 /// XM_006720421 /// XM_006720422 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212700_x_at AJ002220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ002220.1 /DEF=Homo sapiens B2 gene partial cDNA, clone B2E. /FEA=mRNA /DB_XREF=gi:7899287 /UG=Hs.32312 KIAA0356 gene product AJ002220 microRNA 4315-1 /// microRNA 4315-2 /// microRNA 6080 /// pleckstrin homology domain containing, family M (with RUN domain) member 1 /// pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene MIR4315-1 /// MIR4315-2 /// MIR6080 /// PLEKHM1 /// PLEKHM1P 9842 /// 440456 /// 100422961 /// 100423004 /// 102464831 NM_014798 /// NR_024386 /// NR_027774 /// NR_027782 /// NR_036199 /// NR_036271 /// NR_106728 /// XM_006722201 /// XM_006722202 /// XM_006725277 /// XM_006725278 /// XM_006725632 /// XM_006725633 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212701_at AB002318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002318.1 /DEF=Human mRNA for KIAA0320 gene, partial cds. /FEA=mRNA /GEN=KIAA0320 /DB_XREF=gi:2224580 /UG=Hs.150443 KIAA0320 protein AB002318 talin 2 TLN2 83660 NM_015059 /// XM_005254707 /// XM_005254708 /// XM_005254710 /// XM_005254711 /// XM_005254712 /// XM_005254713 /// XM_005254714 /// XM_005254715 /// XM_006720716 /// XM_006720717 /// XM_006720718 /// XM_006720719 /// XM_006720720 /// XM_006720721 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred by curator /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212702_s_at N45111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N45111 /FEA=EST /DB_XREF=gi:1186277 /DB_XREF=est:yz12f12.s1 /CLONE=IMAGE:282863 /UG=Hs.330988 Homo sapiens, Similar to Bicaudal D (Drosophila) homolog 1, clone IMAGE:3622452, mRNA, partial cds N45111 bicaudal D homolog 2 (Drosophila) BICD2 23299 NM_001003800 /// NM_015250 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0072385 // minus-end-directed organelle transport along microtubule // inferred from sequence or structural similarity /// 0072393 // microtubule anchoring at microtubule organizing center // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity 212703_at AV728958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV728958 /FEA=EST /DB_XREF=gi:10838379 /DB_XREF=est:AV728958 /CLONE=HTCBYF04 /UG=Hs.150443 KIAA0320 protein AV728958 talin 2 TLN2 83660 NM_015059 /// XM_005254707 /// XM_005254708 /// XM_005254710 /// XM_005254711 /// XM_005254712 /// XM_005254713 /// XM_005254714 /// XM_005254715 /// XM_006720716 /// XM_006720717 /// XM_006720718 /// XM_006720719 /// XM_006720720 /// XM_006720721 0007016 // cytoskeletal anchoring at plasma membrane // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred by curator /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212704_at AI049962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI049962 /FEA=EST /DB_XREF=gi:3299079 /DB_XREF=est:an38e10.x1 /CLONE=IMAGE:1700970 /UG=Hs.12413 KIAA0191 protein AI049962 zinc finger, CCHC domain containing 11 ZCCHC11 23318 NM_001009881 /// NM_001009882 /// NM_015269 /// XM_005270676 /// XM_005270678 /// XM_005270679 /// XM_005270680 /// XM_005270681 /// XM_005270682 /// XM_005270683 /// XM_005270684 /// XM_005270685 /// XM_006710498 /// XM_006710499 /// XM_006710500 0001816 // cytokine production // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010586 // miRNA metabolic process // inferred from sequence or structural similarity /// 0010587 // miRNA catabolic process // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from mutant phenotype /// 0031123 // RNA 3'-end processing // inferred from direct assay /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050265 // RNA uridylyltransferase activity // inferred from direct assay 212705_x_at BF570210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF570210 /FEA=EST /DB_XREF=gi:11643922 /DB_XREF=est:602185596T1 /CLONE=IMAGE:4310254 /UG=Hs.118463 transport-secretion protein 2.2, BF570210 patatin-like phospholipase domain containing 2 PNPLA2 57104 NM_020376 /// XM_003403858 /// XM_006718265 /// XM_006718266 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 212706_at AB011110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011110.2 /DEF=Homo sapiens mRNA for KIAA0538 protein, partial cds. /FEA=mRNA /GEN=KIAA0538 /PROD=KIAA0538 protein /DB_XREF=gi:6635196 /UG=Hs.184367 GTPase activating protein-like AB011110 uncharacterized LOC102724229 /// RAS p21 protein activator 4 /// RAS p21 protein activator 4B LOC102724229 /// RASA4 /// RASA4B 10156 /// 100271927 /// 102724229 NM_001079877 /// NM_001277335 /// NM_006989 /// XM_005250084 /// XM_005250085 /// XM_005250104 /// XM_006715828 /// XM_006715829 /// XM_006716222 /// XR_428162 /// XR_428163 /// XR_428164 /// XR_428165 0007165 // signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212707_s_at AI738591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738591 /FEA=EST /DB_XREF=gi:5100572 /DB_XREF=est:wi33h07.x1 /CLONE=IMAGE:2392093 /UG=Hs.184367 GTPase activating protein-like AI738591 ras GTPase-activating protein 4-like /// RAS p21 protein activator 4 /// RAS p21 protein activator 4B /// RAS p21 protein activator 4C, pseudogene LOC102725198 /// RASA4 /// RASA4B /// RASA4CP 10156 /// 401331 /// 100271927 /// 102725198 NM_001079877 /// NM_001277335 /// NM_006989 /// NR_024116 /// XM_005250084 /// XM_005250085 /// XM_005250104 /// XM_006715828 /// XM_006715829 /// XM_006726443 /// XM_006726444 /// XM_006726445 /// XR_428162 /// XR_428163 /// XR_428164 /// XR_428165 /// XR_432205 /// XR_432206 0007165 // signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212708_at AV721987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV721987 /FEA=EST /DB_XREF=gi:10824025 /DB_XREF=est:AV721987 /CLONE=HTBAFB10 /UG=Hs.184779 Homo sapiens mRNA; cDNA DKFZp586B1922 (from clone DKFZp586B1922) AV721987 male-specific lethal 1 homolog (Drosophila) MSL1 339287 NM_001012241 /// XM_005257298 /// XM_005257299 0006325 // chromatin organization // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0072487 // MSL complex // inferred from direct assay 212709_at D83781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D83781.1 /DEF=Human mRNA for KIAA0197 gene, partial cds. /FEA=mRNA /GEN=KIAA0197 /DB_XREF=gi:1228044 /UG=Hs.22559 KIAA0197 protein D83781 nucleoporin 160kDa NUP160 23279 NM_015231 /// XM_006718170 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 212710_at AL043774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043774 /FEA=EST /DB_XREF=gi:5423158 /DB_XREF=est:DKFZp434O2027_s1 /CLONE=DKFZp434O2027 /UG=Hs.184793 Homo sapiens cDNA: FLJ21880 fis, clone HEP02743 AL043774 calmodulin regulated spectrin-associated protein 1 CAMSAP1 157922 NM_015447 /// XM_005263396 /// XM_005263397 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from genetic interaction /// 0031175 // neuron projection development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay 212711_at AA019977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA019977 /FEA=EST /DB_XREF=gi:1483694 /DB_XREF=est:ze62g12.s1 /CLONE=IMAGE:363622 /UG=Hs.184793 Homo sapiens cDNA: FLJ21880 fis, clone HEP02743 AA019977 calmodulin regulated spectrin-associated protein 1 CAMSAP1 157922 NM_015447 /// XM_005263396 /// XM_005263397 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from genetic interaction /// 0031175 // neuron projection development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay 212712_at BE222901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222901 /FEA=EST /DB_XREF=gi:8910219 /DB_XREF=est:hu44c03.x1 /CLONE=IMAGE:3172900 /UG=Hs.184793 Homo sapiens cDNA: FLJ21880 fis, clone HEP02743 BE222901 calmodulin regulated spectrin-associated protein 1 CAMSAP1 157922 NM_015447 /// XM_005263396 /// XM_005263397 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from genetic interaction /// 0031175 // neuron projection development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay 212713_at R72286 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R72286 /FEA=EST /DB_XREF=gi:846318 /DB_XREF=est:yj89b06.s1 /CLONE=IMAGE:155891 /UG=Hs.296049 microfibrillar-associated protein 4 R72286 microfibrillar-associated protein 4 MFAP4 4239 NM_001198695 /// NM_002404 0007155 // cell adhesion // inferred from electronic annotation /// 0009650 // UV protection // inferred from direct assay /// 0010712 // regulation of collagen metabolic process // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0048251 // elastic fiber assembly // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay 0001527 // microfibril // inferred from direct assay /// 0001527 // microfibril // non-traceable author statement /// 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071953 // elastic fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212714_at AL050205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050205.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1323 (from clone DKFZp586F1323). /FEA=mRNA /DB_XREF=gi:4884444 /UG=Hs.26613 Homo sapiens mRNA; cDNA DKFZp586F1323 (from clone DKFZp586F1323) AL050205 La ribonucleoprotein domain family, member 4 LARP4 113251 NM_001170803 /// NM_001170804 /// NM_001170808 /// NM_052879 /// NM_199188 /// NM_199190 /// NR_033200 /// XM_005268613 /// XM_006719215 /// XM_006719216 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0016020 // membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212715_s_at AB020626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020626.1 /DEF=Homo sapiens mRNA for KIAA0819 protein, partial cds. /FEA=mRNA /GEN=KIAA0819 /PROD=KIAA0819 protein /DB_XREF=gi:4240123 /UG=Hs.301866 KIAA0819 protein AB020626 microtubule associated monooxygenase, calponin and LIM domain containing 3 MICAL3 57553 NM_001122731 /// NM_001136004 /// NM_015241 /// NM_020793 /// XM_005261262 /// XM_006724081 /// XM_006724082 /// XM_006724083 /// XM_006724084 /// XM_006724085 /// XM_006724086 /// XM_006724087 /// XM_006724088 /// XM_006724089 /// XR_430392 /// XR_430393 0006887 // exocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity 212716_s_at AW083133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW083133 /FEA=EST /DB_XREF=gi:6038285 /DB_XREF=est:xc06e03.x1 /CLONE=IMAGE:2583484 /UG=Hs.324925 LATS (large tumor suppressor, Drosophila) homolog 1 AW083133 eukaryotic translation initiation factor 3, subunit K EIF3K 27335 NM_013234 /// XM_006723147 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation 212717_at AB002354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002354.2 /DEF=Homo sapiens mRNA for KIAA0356 protein, partial cds. /FEA=mRNA /GEN=KIAA0356 /PROD=KIAA0356 protein /DB_XREF=gi:6634022 /UG=Hs.32312 KIAA0356 gene product AB002354 pleckstrin homology domain containing, family M (with RUN domain) member 1 PLEKHM1 9842 NM_014798 /// NR_027774 /// NR_027782 /// XM_006722201 /// XM_006722202 /// XM_006725277 /// XM_006725278 /// XM_006725632 /// XM_006725633 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212718_at BF797555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF797555 /FEA=EST /DB_XREF=gi:12102609 /DB_XREF=est:602257339F1 /CLONE=IMAGE:4340912 /UG=Hs.5324 hypothetical protein BF797555 poly(A) polymerase alpha PAPOLA 10914 NM_001252006 /// NM_001252007 /// NM_001293627 /// NM_001293628 /// NM_001293632 /// NM_032632 /// XM_005267280 /// XM_005267281 /// XM_005267282 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043631 // RNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212719_at AB011178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011178.1 /DEF=Homo sapiens mRNA for KIAA0606 protein, partial cds. /FEA=mRNA /GEN=KIAA0606 /PROD=KIAA0606 protein /DB_XREF=gi:3043735 /UG=Hs.38176 KIAA0606 protein; SCN Circadian Oscillatory Protein (SCOP) AB011178 PH domain and leucine rich repeat protein phosphatase 1 PHLPP1 23239 NM_194449 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212720_at AI670847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI670847 /FEA=EST /DB_XREF=gi:4850578 /DB_XREF=est:wa04h10.x1 /CLONE=IMAGE:2297155 /UG=Hs.5324 hypothetical protein AI670847 poly(A) polymerase alpha PAPOLA 10914 NM_001252006 /// NM_001252007 /// NM_001293627 /// NM_001293628 /// NM_001293632 /// NM_032632 /// XM_005267280 /// XM_005267281 /// XM_005267282 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043631 // RNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 212721_at AI810380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI810380 /FEA=EST /DB_XREF=gi:5396946 /DB_XREF=est:wb87h10.x1 /CLONE=IMAGE:2312707 /UG=Hs.47274 Homo sapiens mRNA; cDNA DKFZp564B176 (from clone DKFZp564B176) AI810380 splicing regulatory glutamine/lysine-rich protein 1 SREK1 140890 NM_001077199 /// NM_001270492 /// NM_001270493 /// NM_139168 /// XM_005248439 /// XM_005248440 /// XM_005248441 /// XM_005248442 /// XM_006714535 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212722_s_at AK021780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021780.1 /DEF=Homo sapiens cDNA FLJ11718 fis, clone HEMBA1005252, highly similar to Homo sapiens mRNA for KIAA0585 protein. /FEA=mRNA /DB_XREF=gi:10433034 /UG=Hs.72660 phosphatidylserine receptor AK021780 jumonji domain containing 6 JMJD6 23210 NM_001081461 /// NM_015167 0001568 // blood vessel development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018395 // peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070078 // histone H3-R2 demethylation // inferred from direct assay /// 0070079 // histone H4-R3 demethylation // inferred from direct assay /// 0070782 // phosphatidylserine exposure on apoptotic cell surface // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0033746 // histone demethylase activity (H3-R2 specific) // inferred from direct assay /// 0033749 // histone demethylase activity (H4-R3 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0070815 // peptidyl-lysine 5-dioxygenase activity // inferred from direct assay 212723_at AK021780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021780.1 /DEF=Homo sapiens cDNA FLJ11718 fis, clone HEMBA1005252, highly similar to Homo sapiens mRNA for KIAA0585 protein. /FEA=mRNA /DB_XREF=gi:10433034 /UG=Hs.72660 phosphatidylserine receptor AK021780 jumonji domain containing 6 JMJD6 23210 NM_001081461 /// NM_015167 0001568 // blood vessel development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018395 // peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070078 // histone H3-R2 demethylation // inferred from direct assay /// 0070079 // histone H4-R3 demethylation // inferred from direct assay /// 0070782 // phosphatidylserine exposure on apoptotic cell surface // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0033746 // histone demethylase activity (H3-R2 specific) // inferred from direct assay /// 0033749 // histone demethylase activity (H4-R3 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0070815 // peptidyl-lysine 5-dioxygenase activity // inferred from direct assay 212724_at BG054844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG054844 /FEA=EST /DB_XREF=gi:12511973 /DB_XREF=est:nac90f11.x1 /CLONE=IMAGE:3441573 /UG=Hs.6838 ras homolog gene family, member E /FL=gb:NM_005168.1 BG054844 Rho family GTPase 3 RND3 390 NM_001254738 /// NM_005168 0006184 // GTP catabolic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 212725_s_at N37081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N37081 /FEA=EST /DB_XREF=gi:1158223 /DB_XREF=est:yy41f04.s1 /CLONE=IMAGE:273823 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) N37081 taurine up-regulated 1 (non-protein coding) TUG1 55000 NR_002323 /// NR_110492 /// NR_110493 212726_at AB014562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014562.1 /DEF=Homo sapiens mRNA for KIAA0662 protein, partial cds. /FEA=mRNA /GEN=KIAA0662 /PROD=KIAA0662 protein /DB_XREF=gi:3327137 /UG=Hs.93868 KIAA0662 gene product AB014562 PHD finger protein 2 PHF2 5253 NM_005392 /// NM_024517 /// XM_005252051 /// XM_006717143 0001889 // liver development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006482 // protein demethylation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061188 // negative regulation of chromatin silencing at rDNA // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 212727_at AB033058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033058.1 /DEF=Homo sapiens mRNA for KIAA1232 protein, partial cds. /FEA=mRNA /GEN=KIAA1232 /PROD=KIAA1232 protein /DB_XREF=gi:6330721 /UG=Hs.11101 KIAA1232 protein AB033058 discs, large homolog 3 (Drosophila) DLG3 1741 NM_001166278 /// NM_020730 /// NM_021120 /// XM_005262248 /// XM_006724625 /// XM_006724626 /// XM_006724627 /// XR_430518 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004385 // guanylate kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 212728_at T62872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T62872 /FEA=EST /DB_XREF=gi:666529 /DB_XREF=est:yc03d01.s1 /CLONE=IMAGE:79585 /UG=Hs.11101 KIAA1232 protein T62872 discs, large homolog 3 (Drosophila) DLG3 1741 NM_001166278 /// NM_020730 /// NM_021120 /// XM_005262248 /// XM_006724625 /// XM_006724626 /// XM_006724627 /// XR_430518 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004385 // guanylate kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 212729_at AI916274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI916274 /FEA=EST /DB_XREF=gi:5636129 /DB_XREF=est:wg99e04.x1 /CLONE=IMAGE:2379390 /UG=Hs.11101 KIAA1232 protein AI916274 discs, large homolog 3 (Drosophila) DLG3 1741 NM_001166278 /// NM_020730 /// NM_021120 /// XM_005262248 /// XM_006724625 /// XM_006724626 /// XM_006724627 /// XR_430518 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004385 // guanylate kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 212730_at AK026420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026420.1 /DEF=Homo sapiens cDNA: FLJ22767 fis, clone KAIA1191. /FEA=mRNA /DB_XREF=gi:10439281 /UG=Hs.10587 KIAA0353 protein AK026420 synemin, intermediate filament protein SYNM 23336 NM_015286 /// NM_145728 0045104 // intermediate filament cytoskeleton organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0005912 // adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // traceable author statement 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0017166 // vinculin binding // inferred from direct assay /// 0019215 // intermediate filament binding // inferred from sequence or structural similarity 212731_at U79297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79297.1 /DEF=Human clone 23589 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710280 /UG=Hs.11506 Human clone 23589 mRNA sequence U79297 ankyrin repeat domain 46 ANKRD46 157567 NM_001270377 /// NM_001270378 /// NM_001270379 /// NM_198401 /// XM_006716509 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212732_at AI950273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI950273 /FEA=EST /DB_XREF=gi:5742583 /DB_XREF=est:wq37h05.x1 /CLONE=IMAGE:2473497 /UG=Hs.112844 maternally expressed 3 AI950273 maternally expressed 3 (non-protein coding) MEG3 55384 NR_002766 /// NR_003530 /// NR_003531 /// NR_033358 /// NR_033359 /// NR_033360 /// NR_046464 /// NR_046465 /// NR_046466 /// NR_046467 /// NR_046468 /// NR_046469 /// NR_046470 /// NR_046471 /// NR_046472 /// NR_046473 212733_at AI798908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI798908 /FEA=EST /DB_XREF=gi:5364380 /DB_XREF=est:we94b11.x1 /CLONE=IMAGE:2348733 /UG=Hs.141296 KIAA0226 gene product AI798908 KIAA0226 KIAA0226 9711 NM_001145642 /// NM_014687 /// XM_005269374 /// XM_006713827 /// XM_006713828 /// XM_006713829 /// XM_006713830 /// XM_006713831 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212734_x_at AI186735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186735 /FEA=EST /DB_XREF=gi:3737373 /DB_XREF=est:qe79b09.x1 /CLONE=IMAGE:1745177 /UG=Hs.180842 ribosomal protein L13 AI186735 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212735_at BF448041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448041 /FEA=EST /DB_XREF=gi:11513102 /DB_XREF=est:7q97f09.x1 /CLONE=IMAGE:3706504 /UG=Hs.141296 KIAA0226 gene product BF448041 KIAA0226 KIAA0226 9711 NM_001145642 /// NM_014687 /// XM_005269374 /// XM_006713827 /// XM_006713828 /// XM_006713829 /// XM_006713830 /// XM_006713831 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212736_at BE299456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE299456 /FEA=EST /DB_XREF=gi:9183204 /DB_XREF=est:600944717T1 /CLONE=IMAGE:2960548 /UG=Hs.6349 Human Chromosome 16 BAC clone CIT987SK-A-362G6 BE299456 chromosome 16 open reading frame 45 C16orf45 89927 NM_001142469 /// NM_033201 0005515 // protein binding // inferred from electronic annotation 212737_at AL513583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL513583 /FEA=EST /DB_XREF=gi:12777077 /DB_XREF=est:AL513583 /CLONE=XCL0BA001ZA05 (3 prime) /UG=Hs.278242 tubulin, alpha, ubiquitous AL513583 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019377 // glycolipid catabolic process // non-traceable author statement /// 0019915 // lipid storage // inferred from electronic annotation /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030290 // sphingolipid activator protein activity // non-traceable author statement 212738_at AV717623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV717623 /FEA=EST /DB_XREF=gi:10814775 /DB_XREF=est:AV717623 /CLONE=DCBBIC10 /UG=Hs.80305 Human clone 23719 mRNA sequence AV717623 Rho GTPase activating protein 19 ARHGAP19 84986 NM_001204300 /// NM_001256423 /// NM_032900 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 212739_s_at AL523860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523860 /FEA=EST /DB_XREF=gi:12787353 /DB_XREF=est:AL523860 /CLONE=CS0DC003YM19 (5 prime) /UG=Hs.9235 non-metastatic cells 4, protein expressed in AL523860 NME/NM23 nucleoside diphosphate kinase 4 NME4 4833 NM_001286433 /// NM_001286435 /// NM_001286436 /// NM_001286438 /// NM_001286439 /// NM_001286440 /// NM_005009 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212740_at BF740111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF740111 /FEA=EST /DB_XREF=gi:12066787 /DB_XREF=est:7n12e08.x1 /CLONE=IMAGE:3564398 /UG=Hs.83050 phosphoinositide-3-kinase, regulatory subunit 4, p150 BF740111 phosphoinositide-3-kinase, regulatory subunit 4 PIK3R4 30849 NM_014602 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212741_at AA923354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA923354 /FEA=EST /DB_XREF=gi:3070663 /DB_XREF=est:ol46a12.s1 /CLONE=IMAGE:1526494 /UG=Hs.183109 monoamine oxidase A AA923354 monoamine oxidase A MAOA 4128 NM_000240 /// NM_001270458 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008131 // primary amine oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 212742_at AL530462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL530462 /FEA=EST /DB_XREF=gi:12793955 /DB_XREF=est:AL530462 /CLONE=CS0DD007YH21 (3 prime) /UG=Hs.16537 hypothetical protein, similar to (U06944) PRAJA1 AL530462 ring finger protein 115 RNF115 27246 NM_014455 /// XM_005272952 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212743_at AV694093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV694093 /FEA=EST /DB_XREF=gi:10295956 /DB_XREF=est:AV694093 /CLONE=GKCDSD10 /UG=Hs.48297 DKFZP586C1620 protein AV694093 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase RCHY1 25898 NM_001008925 /// NM_001009922 /// NM_001278536 /// NM_001278537 /// NM_001278538 /// NM_001278539 /// NM_015436 /// NR_037913 /// NR_037914 /// NR_103723 /// NR_103724 /// NR_103725 /// XM_006714174 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212744_at AI813772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI813772 /FEA=EST /DB_XREF=gi:5424987 /DB_XREF=est:wk79d07.x1 /CLONE=IMAGE:2421613 /UG=Hs.26471 Homo sapiens clone HQ0692 AI813772 Bardet-Biedl syndrome 4 BBS4 585 NM_001252678 /// NM_033028 /// NR_045565 /// NR_045566 /// XM_006720623 /// XM_006720624 /// XM_006720625 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001895 // retina homeostasis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0021756 // striatum development // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030534 // adult behavior // inferred from sequence or structural similarity /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0033210 // leptin-mediated signaling pathway // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from mutant phenotype /// 0035058 // nonmotile primary cilium assembly // inferred from sequence or structural similarity /// 0038108 // negative regulation of appetite by leptin-mediated signaling pathway // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0044321 // response to leptin // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0045724 // positive regulation of cilium assembly // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from sequence or structural similarity /// 0046907 // intracellular transport // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050893 // sensory processing // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from genetic interaction /// 0051877 // pigment granule aggregation in cell center // inferred from sequence or structural similarity /// 0060027 // convergent extension involved in gastrulation // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060296 // regulation of cilium beat frequency involved in ciliary motility // inferred from sequence or structural similarity /// 0071539 // protein localization to centrosome // inferred from mutant phenotype 0000242 // pericentriolar material // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031514 // motile cilium // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0034464 // BBSome // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003777 // microtubule motor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0034452 // dynactin binding // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay 212745_s_at AI813772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI813772 /FEA=EST /DB_XREF=gi:5424987 /DB_XREF=est:wk79d07.x1 /CLONE=IMAGE:2421613 /UG=Hs.26471 Homo sapiens clone HQ0692 AI813772 Bardet-Biedl syndrome 4 BBS4 585 NM_001252678 /// NM_033028 /// NR_045565 /// NR_045566 /// XM_006720623 /// XM_006720624 /// XM_006720625 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001895 // retina homeostasis // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0021756 // striatum development // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030534 // adult behavior // inferred from sequence or structural similarity /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0033210 // leptin-mediated signaling pathway // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from mutant phenotype /// 0035058 // nonmotile primary cilium assembly // inferred from sequence or structural similarity /// 0038108 // negative regulation of appetite by leptin-mediated signaling pathway // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0044321 // response to leptin // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0045724 // positive regulation of cilium assembly // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from sequence or structural similarity /// 0046907 // intracellular transport // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050893 // sensory processing // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from genetic interaction /// 0051877 // pigment granule aggregation in cell center // inferred from sequence or structural similarity /// 0060027 // convergent extension involved in gastrulation // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060296 // regulation of cilium beat frequency involved in ciliary motility // inferred from sequence or structural similarity /// 0071539 // protein localization to centrosome // inferred from mutant phenotype 0000242 // pericentriolar material // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031514 // motile cilium // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0034464 // BBSome // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003777 // microtubule motor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0034452 // dynactin binding // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay 212746_s_at AA126789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA126789 /FEA=EST /DB_XREF=gi:1686271 /DB_XREF=est:zn87e10.s1 /CLONE=IMAGE:565194 /UG=Hs.25132 KIAA0470 gene product AA126789 centrosomal protein 170kDa /// centrosomal protein 170kDa pseudogene 1 CEP170 /// CEP170P1 9859 /// 645455 NM_001042404 /// NM_001042405 /// NM_014812 /// NM_153243 /// NR_003135 /// XM_005273361 /// XM_006711843 /// XM_006711844 /// XM_006711845 /// XM_006711846 /// XM_006711847 /// XM_006711848 /// XM_006711849 /// XM_006711850 /// XM_006711851 /// XM_006711852 /// XM_006724974 /// XM_006724975 /// XM_006724976 /// XM_006724977 /// XM_006724978 /// XM_006724979 /// XM_006724980 /// XM_006724981 /// XM_006724982 /// XM_006724983 /// XM_006724984 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 212747_at AI990523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI990523 /FEA=EST /DB_XREF=gi:5837404 /DB_XREF=est:ws40g04.x1 /CLONE=IMAGE:2499702 /UG=Hs.20060 KIAA0229 protein AI990523 ankyrin repeat and sterile alpha motif domain containing 1A ANKS1A 23294 NM_015245 /// XM_005248964 /// XM_006715033 /// XM_006715034 /// XM_006715035 /// XM_006715036 /// XM_006715037 /// XM_006715038 0006929 // substrate-dependent cell migration // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from electronic annotation 212748_at AB037859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037859.1 /DEF=Homo sapiens mRNA for KIAA1438 protein, partial cds. /FEA=mRNA /GEN=KIAA1438 /PROD=KIAA1438 protein /DB_XREF=gi:7243273 /UG=Hs.31146 KIAA1438 protein AB037859 megakaryoblastic leukemia (translocation) 1 MKL1 57591 NM_001282660 /// NM_001282661 /// NM_001282662 /// NM_020831 /// XM_005261691 /// XM_005261692 /// XM_005261694 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048536 // spleen development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from mutant phenotype /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212749_s_at AI096477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI096477 /FEA=EST /DB_XREF=gi:3445971 /DB_XREF=est:qa03c06.x1 /CLONE=IMAGE:1685674 /UG=Hs.48297 DKFZP586C1620 protein AI096477 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase RCHY1 25898 NM_001008925 /// NM_001009922 /// NM_001278536 /// NM_001278537 /// NM_001278538 /// NM_001278539 /// NM_015436 /// NR_037913 /// NR_037914 /// NR_103723 /// NR_103724 /// NR_103725 /// XM_006714174 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212750_at AB020630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020630.1 /DEF=Homo sapiens mRNA for KIAA0823 protein, partial cds. /FEA=mRNA /GEN=KIAA0823 /PROD=KIAA0823 protein /DB_XREF=gi:4240131 /UG=Hs.45719 KIAA0823 protein AB020630 protein phosphatase 1, regulatory subunit 16B PPP1R16B 26051 NM_001172735 /// NM_015568 0007165 // signal transduction // non-traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // non-traceable author statement 212751_at BG290646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG290646 /FEA=EST /DB_XREF=gi:13047817 /DB_XREF=est:602388931F1 /CLONE=IMAGE:4517935 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) BG290646 ubiquitin-conjugating enzyme E2N UBE2N 7334 NM_003348 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212752_at AA176798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA176798 /FEA=EST /DB_XREF=gi:1757939 /DB_XREF=est:zp32e12.s1 /CLONE=IMAGE:611182 /UG=Hs.11238 KIAA0622 protein; Drosophila multiple asters (Mast)-like homolog 1 AA176798 cytoplasmic linker associated protein 1 CLASP1 23332 NM_001142273 /// NM_001142274 /// NM_001207051 /// NM_015282 /// XM_006712373 /// XM_006712374 /// XM_006712375 /// XM_006712376 /// XM_006712377 /// XM_006712378 /// XM_006712379 /// XM_006712380 /// XM_006712381 /// XM_006712382 /// XM_006712383 /// XM_006712384 /// XM_006712385 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from genetic interaction /// 0000278 // mitotic cell cycle // traceable author statement /// 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0007020 // microtubule nucleation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from genetic interaction /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0031111 // negative regulation of microtubule polymerization or depolymerization // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from direct assay /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005828 // kinetochore microtubule // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay /// 0031592 // centrosomal corona // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0043515 // kinetochore binding // inferred from mutant phenotype /// 0051010 // microtubule plus-end binding // inferred from direct assay 212753_at AI692203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI692203 /FEA=EST /DB_XREF=gi:4969543 /DB_XREF=est:wd37h12.x1 /CLONE=IMAGE:2330375 /UG=Hs.8834 ring finger protein 3 AI692203 polycomb group ring finger 3 PCGF3 10336 NM_006315 /// XM_005272250 /// XM_005272252 /// XM_005272253 /// XM_005272254 /// XM_006713852 /// XM_006713853 /// XM_006713854 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212754_s_at AI760249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760249 /FEA=EST /DB_XREF=gi:5175916 /DB_XREF=est:wg59b04.x1 /CLONE=IMAGE:2369359 /UG=Hs.9846 KIAA1040 protein AI760249 MON2 homolog (S. cerevisiae) MON2 23041 NM_001278469 /// NM_001278470 /// NM_001278471 /// NM_001278472 /// NM_015026 /// XM_005268731 /// XM_005268732 /// XM_005268734 /// XM_005268735 /// XM_005268736 /// XR_429085 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0043087 // regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // 0005802 // trans-Golgi network // not recorded 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212755_at BG548738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG548738 /FEA=EST /DB_XREF=gi:13547403 /DB_XREF=est:602576358F1 /CLONE=IMAGE:4704327 /UG=Hs.9846 KIAA1040 protein BG548738 MON2 homolog (S. cerevisiae) MON2 23041 NM_001278469 /// NM_001278470 /// NM_001278471 /// NM_001278472 /// NM_015026 /// XM_005268731 /// XM_005268732 /// XM_005268734 /// XM_005268735 /// XM_005268736 /// XR_429085 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0043087 // regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // 0005802 // trans-Golgi network // not recorded 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212756_s_at AI761518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761518 /FEA=EST /DB_XREF=gi:5177185 /DB_XREF=est:wi61d01.x1 /CLONE=IMAGE:2394721 /UG=Hs.15303 KIAA0349 protein AI761518 ubiquitin protein ligase E3 component n-recognin 2 UBR2 23304 NM_001184801 /// NM_015255 /// XM_005248965 /// XM_005248966 0006342 // chromatin silencing // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0033522 // histone H2A ubiquitination // inferred from sequence or structural similarity /// 0071233 // cellular response to leucine // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070728 // leucine binding // inferred from direct assay 212757_s_at BF111268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF111268 /FEA=EST /DB_XREF=gi:10940958 /DB_XREF=est:7l74d02.x1 /CLONE=IMAGE:3527090 /UG=Hs.12436 Homo sapiens cDNA: FLJ22656 fis, clone HSI07655 BF111268 calcium/calmodulin-dependent protein kinase II gamma CAMK2G 818 NM_001204492 /// NM_001222 /// NM_172169 /// NM_172170 /// NM_172171 /// NM_172172 /// NM_172173 /// XM_005270195 /// XM_005270197 /// XM_005270198 /// XM_005270199 /// XM_005270200 /// XM_005270201 /// XM_005270202 /// XM_005270203 /// XM_005270205 /// XM_006717993 /// XM_006717994 /// XM_006717995 /// XM_006717996 /// XM_006717997 /// XM_006717998 /// XM_006717999 /// XM_006718000 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030073 // insulin secretion // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 1901897 // regulation of relaxation of cardiac muscle // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212758_s_at AI373166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI373166 /FEA=EST /DB_XREF=gi:4153032 /DB_XREF=est:qz13b01.x1 /CLONE=IMAGE:2021353 /UG=Hs.232068 transcription factor 8 (represses interleukin 2 expression) AI373166 uncharacterized LOC100996668 /// zinc finger E-box binding homeobox 1 LOC100996668 /// ZEB1 6935 /// 100996668 NM_001128128 /// NM_001174093 /// NM_001174094 /// NM_001174095 /// NM_001174096 /// NM_030751 /// NR_024285 /// NR_024286 /// NR_024287 /// XM_005252575 /// XM_005252576 /// XM_006717497 /// XM_006717498 /// XM_006717499 /// XR_158862 /// XR_159196 /// XR_171848 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010464 // regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212759_s_at AI703074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI703074 /FEA=EST /DB_XREF=gi:4990974 /DB_XREF=est:wd81e06.x1 /CLONE=IMAGE:2338018 /UG=Hs.173638 transcription factor 7-like 2 (T-cell specific, HMG-box) AI703074 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 212760_at AB002347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002347.1 /DEF=Human mRNA for KIAA0349 gene, partial cds. /FEA=mRNA /GEN=KIAA0349 /DB_XREF=gi:2224638 /UG=Hs.15303 KIAA0349 protein AB002347 ubiquitin protein ligase E3 component n-recognin 2 UBR2 23304 NM_001184801 /// NM_015255 /// XM_005248965 /// XM_005248966 0006342 // chromatin silencing // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0033522 // histone H2A ubiquitination // inferred from sequence or structural similarity /// 0071233 // cellular response to leucine // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070728 // leucine binding // inferred from direct assay 212761_at AI949687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI949687 /FEA=EST /DB_XREF=gi:5741997 /DB_XREF=est:wq13g04.x1 /CLONE=IMAGE:2471190 /UG=Hs.173638 transcription factor 7-like 2 (T-cell specific, HMG-box) AI949687 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 212762_s_at AI375916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375916 /FEA=EST /DB_XREF=gi:4175906 /DB_XREF=est:tc14c12.x1 /CLONE=IMAGE:2063830 /UG=Hs.173638 transcription factor 7-like 2 (T-cell specific, HMG-box) AI375916 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 212763_at AW593213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW593213 /FEA=EST /DB_XREF=gi:7280471 /DB_XREF=est:hg11b09.x1 /CLONE=IMAGE:2945273 /UG=Hs.23585 KIAA1078 protein AW593213 calmodulin regulated spectrin-associated protein family, member 2 CAMSAP2 23271 NM_203459 /// XM_005245040 /// XM_005245041 /// XM_005245042 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0033043 // regulation of organelle organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0051011 // microtubule minus-end binding // inferred from direct assay 212764_at AI806174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806174 /FEA=EST /DB_XREF=gi:5392740 /DB_XREF=est:wf06h03.x1 /CLONE=IMAGE:2349845 /UG=Hs.232068 transcription factor 8 (represses interleukin 2 expression) AI806174 uncharacterized LOC100996668 /// zinc finger E-box binding homeobox 1 LOC100996668 /// ZEB1 6935 /// 100996668 NM_001128128 /// NM_001174093 /// NM_001174094 /// NM_001174095 /// NM_001174096 /// NM_030751 /// NR_024285 /// NR_024286 /// NR_024287 /// XM_005252575 /// XM_005252576 /// XM_006717497 /// XM_006717498 /// XM_006717499 /// XR_158862 /// XR_159196 /// XR_171848 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010464 // regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 212765_at AB029001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029001.1 /DEF=Homo sapiens mRNA for KIAA1078 protein, partial cds. /FEA=mRNA /GEN=KIAA1078 /PROD=KIAA1078 protein /DB_XREF=gi:5689492 /UG=Hs.23585 KIAA1078 protein AB029001 calmodulin regulated spectrin-associated protein family, member 2 CAMSAP2 23271 NM_203459 /// XM_005245040 /// XM_005245041 /// XM_005245042 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0033043 // regulation of organelle organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0051011 // microtubule minus-end binding // inferred from direct assay 212766_s_at AW294587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW294587 /FEA=EST /DB_XREF=gi:6701223 /DB_XREF=est:UI-H-BI2-ahk-f-08-0-UI.s1 /CLONE=IMAGE:2727302 /UG=Hs.301904 Homo sapiens, Similar to hypothetical protein FLJ12484, clone MGC:3008, mRNA, complete cds AW294587 interferon stimulated exonuclease gene 20kDa-like 2 ISG20L2 81875 NM_030980 /// XM_005245516 /// XM_005245517 /// XM_005245518 /// XM_006711560 /// XM_006711561 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212767_at BC004409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004409.1 /DEF=Homo sapiens, clone IMAGE:3638994, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3638994) /DB_XREF=gi:13325181 /UG=Hs.301693 Homo sapiens, clone IMAGE:3638994, mRNA, partial cds BC004409 mitochondrial ribosome-associated GTPase 1 MTG1 92170 NM_138384 0006184 // GTP catabolic process // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from direct assay /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008215 // spermine metabolic process // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from direct assay /// 0009447 // putrescine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042254 // ribosome biogenesis // not recorded /// 0044065 // regulation of respiratory system process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046203 // spermidine catabolic process // inferred from direct assay /// 0046203 // spermidine catabolic process // inferred from electronic annotation /// 0046208 // spermine catabolic process // inferred from direct assay /// 0046208 // spermine catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070129 // regulation of mitochondrial translation // inferred from mutant phenotype /// 1901307 // positive regulation of spermidine biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046592 // polyamine oxidase activity // inferred from direct assay /// 0046592 // polyamine oxidase activity // inferred from electronic annotation /// 0052899 // N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052901 // spermine:oxygen oxidoreductase (spermidine-forming) activity // inferred from electronic annotation /// 0052902 // spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity // inferred from electronic annotation /// 0052903 // N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052904 // N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052904 // N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // traceable author statement 212768_s_at AL390736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390736 /DEF=Human DNA sequence from clone RP11-209J19 on chromosome 13 Contains ESTs, STSs and GSSs. Contains the gene for the GW112 protein with two isoforms (GW112 and KIAA4294) /FEA=mRNA /DB_XREF=gi:11182238 /UG=Hs.273321 differentially expressed in hematopoietic lineages AL390736 olfactomedin 4 OLFM4 10562 NM_006418 0007155 // cell adhesion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010939 // regulation of necrotic cell death // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0050764 // regulation of phagocytosis // inferred from mutant phenotype /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2000389 // regulation of neutrophil extravasation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0045296 // cadherin binding // inferred from mutant phenotype 212769_at AI567426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI567426 /FEA=EST /DB_XREF=gi:4525878 /DB_XREF=est:tn38b04.x1 /CLONE=IMAGE:2169871 /UG=Hs.31305 KIAA1547 protein AI567426 transducin-like enhancer of split 3 TLE3 7090 NM_001105192 /// NM_001282979 /// NM_001282980 /// NM_001282981 /// NM_001282982 /// NM_005078 /// NM_020908 /// XM_005254622 /// XM_005254623 /// XM_005254625 /// XM_005254628 /// XM_005254633 /// XM_006720662 /// XM_006720663 /// XM_006720664 /// XM_006720665 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 212770_at AW873621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW873621 /FEA=EST /DB_XREF=gi:8007674 /DB_XREF=est:ho64d03.x1 /CLONE=IMAGE:3042149 /UG=Hs.31305 KIAA1547 protein AW873621 transducin-like enhancer of split 3 TLE3 7090 NM_001105192 /// NM_001282979 /// NM_001282980 /// NM_001282981 /// NM_001282982 /// NM_005078 /// NM_020908 /// XM_005254622 /// XM_005254623 /// XM_005254625 /// XM_005254628 /// XM_005254633 /// XM_006720662 /// XM_006720663 /// XM_006720664 /// XM_006720665 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 212771_at AU150943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150943 /FEA=EST /DB_XREF=gi:11012464 /DB_XREF=est:AU150943 /CLONE=NT2RP2003984 /UG=Hs.66762 Homo sapiens mRNA; cDNA DKFZp564A026 (from clone DKFZp564A026) AU150943 family with sequence similarity 171, member A1 FAM171A1 221061 NM_001010924 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 212772_s_at AL162060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162060.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547P193 (from clone DKFZp547P193); partial cds. /FEA=mRNA /GEN=DKFZp547P193 /PROD=hypothetical protein /DB_XREF=gi:7328110 /UG=Hs.94806 KIAA1062 protein AL162060 ATP-binding cassette, sub-family A (ABC1), member 2 ABCA2 20 NM_001606 /// NM_212533 /// XM_006716996 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032383 // regulation of intracellular cholesterol transport // inferred from mutant phenotype /// 0042493 // response to drug // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from expression pattern /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0055085 // transmembrane transport // non-traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from reviewed computational analysis /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from reviewed computational analysis /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement 0000166 // nucleotide binding // inferred from reviewed computational analysis /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement 212773_s_at BG165094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG165094 /FEA=EST /DB_XREF=gi:12671797 /DB_XREF=est:602343902F1 /CLONE=IMAGE:4453945 /UG=Hs.75187 translocase of outer mitochondrial membrane 20 (yeast) homolog BG165094 translocase of outer mitochondrial membrane 20 homolog (yeast) TOMM20 9804 NM_014765 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // non-traceable author statement /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 212774_at AJ223321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ223321 /DEF=Homo sapiens RP58 gene, complete CDS /FEA=mRNA /DB_XREF=gi:4128144 /UG=Hs.69997 zinc finger protein 238 AJ223321 zinc finger and BTB domain containing 18 ZBTB18 10472 NM_001278196 /// NM_006352 /// NM_205768 /// XM_005273006 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051302 // regulation of cell division // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212775_at AI978623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI978623 /FEA=EST /DB_XREF=gi:5803653 /DB_XREF=est:wr57d03.x1 /CLONE=IMAGE:2491781 /UG=Hs.6654 KIAA0657 protein AI978623 obscurin-like 1 OBSL1 23363 NM_001173408 /// NM_001173431 /// NM_015311 /// XM_005246421 /// XM_005246423 /// XM_005246424 /// XM_005246425 /// XM_005246427 /// XM_006712386 /// XM_006712387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0050775 // positive regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0014704 // intercalated disc // traceable author statement /// 0030018 // Z disc // traceable author statement /// 0031430 // M band // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // traceable author statement /// 1990393 // 3M complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation 212776_s_at AI978623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI978623 /FEA=EST /DB_XREF=gi:5803653 /DB_XREF=est:wr57d03.x1 /CLONE=IMAGE:2491781 /UG=Hs.6654 KIAA0657 protein AI978623 obscurin-like 1 OBSL1 23363 NM_001173408 /// NM_001173431 /// NM_015311 /// XM_005246421 /// XM_005246423 /// XM_005246424 /// XM_005246425 /// XM_005246427 /// XM_006712386 /// XM_006712387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0050775 // positive regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0014704 // intercalated disc // traceable author statement /// 0030018 // Z disc // traceable author statement /// 0031430 // M band // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // traceable author statement /// 1990393 // 3M complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation 212777_at L13857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13857.1 /DEF=Human guanine nucleotide exchange factor mRNA, complete cds. /FEA=CDS /PROD=guanine nucleotide exchange factor /DB_XREF=gi:306777 /UG=Hs.326392 son of sevenless (Drosophila) homolog 1 /FL=gb:L13857.1 L13857 son of sevenless homolog 1 (Drosophila) SOS1 6654 NM_005633 /// XM_005264515 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032318 // regulation of Ras GTPase activity // not recorded /// 0032318 // regulation of Ras GTPase activity // traceable author statement /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // not recorded /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212778_at AL583340 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583340 /FEA=EST /DB_XREF=gi:12952206 /DB_XREF=est:AL583340 /CLONE=CS0DL012YA08 (3 prime) /UG=Hs.37656 KIAA0602 protein AL583340 phosphofurin acidic cluster sorting protein 2 PACS2 23241 NM_001100913 /// NM_001243127 /// NM_015197 /// XM_005267462 /// XM_005267463 /// XM_006720085 /// XM_006720086 /// XM_006720087 /// XM_006720088 /// XM_006720089 /// XM_006720090 /// XM_006720091 /// XM_006720092 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 212779_at AB029032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029032.1 /DEF=Homo sapiens mRNA for KIAA1109 protein, partial cds. /FEA=mRNA /GEN=KIAA1109 /PROD=KIAA1109 protein /DB_XREF=gi:5689554 /UG=Hs.6606 KIAA1109 protein AB029032 KIAA1109 KIAA1109 84162 NM_015312 /// NM_032202 /// XM_005263282 /// XM_005263283 /// XM_005263284 /// XM_005263285 /// XM_005263286 /// XM_005263287 /// XM_005263288 /// XM_005263289 /// XM_005263290 /// XM_005263291 /// XM_005263292 /// XM_006714342 /// XM_006714343 /// XM_006714344 0001558 // regulation of cell growth // non-traceable author statement /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212780_at AA700167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA700167 /FEA=EST /DB_XREF=gi:2703130 /DB_XREF=est:zj36h12.s1 /CLONE=IMAGE:452423 /UG=Hs.326392 son of sevenless (Drosophila) homolog 1 /FL=gb:L13857.1 AA700167 son of sevenless homolog 1 (Drosophila) SOS1 6654 NM_005633 /// XM_005264515 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032318 // regulation of Ras GTPase activity // not recorded /// 0032318 // regulation of Ras GTPase activity // traceable author statement /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // not recorded /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212781_at AK026954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026954.1 /DEF=Homo sapiens cDNA: FLJ23301 fis, clone HEP11120. /FEA=mRNA /DB_XREF=gi:10439935 /UG=Hs.91065 hypothetical protein DKFZp761B2423 AK026954 retinoblastoma binding protein 6 RBBP6 5930 NM_006910 /// NM_018703 /// NM_032626 /// XM_005255461 /// XM_005255462 0001701 // in utero embryonic development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0061053 // somite development // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212782_x_at BG335629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG335629 /FEA=EST /DB_XREF=gi:13142067 /DB_XREF=est:602404254F1 /CLONE=IMAGE:4542084 /UG=Hs.80475 polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) BG335629 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa POLR2J 5439 NM_006234 /// XM_005250452 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 212783_at AI538172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI538172 /FEA=EST /DB_XREF=gi:4452307 /DB_XREF=est:ti75f08.x1 /CLONE=IMAGE:2137863 /UG=Hs.91065 hypothetical protein DKFZp761B2423 AI538172 retinoblastoma binding protein 6 RBBP6 5930 NM_006910 /// NM_018703 /// NM_032626 /// XM_005255461 /// XM_005255462 0001701 // in utero embryonic development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0061053 // somite development // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212784_at AB002304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002304.1 /DEF=Human mRNA for KIAA0306 gene, partial cds. /FEA=mRNA /GEN=KIAA0306 /DB_XREF=gi:2224552 /UG=Hs.94970 KIAA0306 protein /FL=gb:NM_015125.1 AB002304 capicua transcriptional repressor CIC 23152 NM_015125 /// XM_005258673 /// XM_005258674 /// XM_005258675 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212785_s_at AA160181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA160181 /FEA=EST /DB_XREF=gi:1734757 /DB_XREF=est:zo81d09.s1 /CLONE=IMAGE:593297 /UG=Hs.278635 HDCMA18P protein AA160181 La ribonucleoprotein domain family, member 7 LARP7 51574 NM_001267039 /// NM_015454 /// NM_016648 /// NR_049768 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212786_at AA731693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA731693 /FEA=EST /DB_XREF=gi:2752582 /DB_XREF=est:nw70a03.s1 /CLONE=IMAGE:1251916 /UG=Hs.23263 KIAA0350 protein AA731693 C-type lectin domain family 16, member A CLEC16A 23274 NM_001243403 /// NM_015226 /// XM_005255210 /// XM_005255211 /// XM_005255213 /// XM_005255214 /// XM_005255215 /// XM_005255216 /// XM_006720870 212787_at AI952986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI952986 /FEA=EST /DB_XREF=gi:5745296 /DB_XREF=est:wp98b10.x1 /CLONE=IMAGE:2469787 /UG=Hs.159471 ZAP3 protein AI952986 YLP motif containing 1 YLPM1 56252 NM_019589 /// XM_005267860 /// XR_245704 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032204 // regulation of telomere maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212788_x_at BG537190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG537190 /FEA=EST /DB_XREF=gi:13528922 /DB_XREF=est:602565589F1 /CLONE=IMAGE:4690079 /UG=Hs.111334 ferritin, light polypeptide BG537190 ferritin, light polypeptide FTL 2512 NM_000146 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0055072 // iron ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0008043 // intracellular ferritin complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 212789_at AI796581 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796581 /FEA=EST /DB_XREF=gi:5362044 /DB_XREF=est:wh58a06.x1 /CLONE=IMAGE:2384914 /UG=Hs.13421 KIAA0056 protein AI796581 non-SMC condensin II complex, subunit D3 NCAPD3 23310 NM_015261 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000799 // nuclear condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from direct assay /// 0042585 // germinal vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 212790_x_at BF942308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF942308 /FEA=EST /DB_XREF=gi:12359628 /DB_XREF=est:nae91f11.x1 /CLONE=IMAGE:4119332 /UG=Hs.119122 ribosomal protein L13a BF942308 ribosomal protein L13a /// ribosomal protein L13a pseudogene 5 /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A RPL13A /// RPL13AP5 /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 /// 728658 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_026712 /// NR_073024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212791_at AL042729 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL042729 /FEA=EST /DB_XREF=gi:5935545 /DB_XREF=est:DKFZp434B0222_s1 /CLONE=DKFZp434B0222 /UG=Hs.112023 ESTs AL042729 chromosome 1 open reading frame 216 C1orf216 127703 NM_152374 212792_at AB020684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020684.1 /DEF=Homo sapiens mRNA for KIAA0877 protein, partial cds. /FEA=mRNA /GEN=KIAA0877 /PROD=KIAA0877 protein /DB_XREF=gi:4240242 /UG=Hs.11217 KIAA0877 protein AB020684 dpy-19-like 1 (C. elegans) DPY19L1 23333 NM_015283 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 212793_at BF513244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF513244 /FEA=EST /DB_XREF=gi:11598423 /DB_XREF=est:UI-H-BW1-amo-b-04-0-UI.s1 /CLONE=IMAGE:3070422 /UG=Hs.100113 KIAA0381 protein BF513244 dishevelled associated activator of morphogenesis 2 DAAM2 23500 NM_001201427 /// NM_015345 /// XM_006715039 /// XM_006715040 /// XM_006715041 /// XM_006715042 /// XM_006715043 /// XM_006715044 /// XM_006715045 /// XM_006715046 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 212794_s_at AK001728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001728.1 /DEF=Homo sapiens cDNA FLJ10866 fis, clone NT2RP4001614. /FEA=mRNA /DB_XREF=gi:7023169 /UG=Hs.12144 KIAA1033 protein AK001728 KIAA1033 KIAA1033 23325 NM_001293640 /// NM_015275 /// XM_005268742 /// XM_005268743 /// XM_005268744 /// XM_005268745 /// XM_005268746 /// XR_245916 0016197 // endosomal transport // inferred from mutant phenotype /// 0016197 // endosomal transport // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 212795_at AL137753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137753.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1412 (from clone DKFZp434K1412). /FEA=mRNA /DB_XREF=gi:6808455 /UG=Hs.12144 KIAA1033 protein AL137753 KIAA1033 KIAA1033 23325 NM_001293640 /// NM_015275 /// XM_005268742 /// XM_005268743 /// XM_005268744 /// XM_005268745 /// XM_005268746 /// XR_245916 0016197 // endosomal transport // inferred from mutant phenotype /// 0016197 // endosomal transport // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 212796_s_at BF195608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195608 /FEA=EST /DB_XREF=gi:11082676 /DB_XREF=est:7n85f03.x1 /CLONE=IMAGE:3571349 /UG=Hs.126084 KIAA1055 protein BF195608 TBC1 domain family, member 2B TBC1D2B 23102 NM_015079 /// NM_144572 /// XM_005254242 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 212797_at BE742268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE742268 /FEA=EST /DB_XREF=gi:10156260 /DB_XREF=est:601575686F1 /CLONE=IMAGE:3836709 /UG=Hs.281706 sortilin 1 BE742268 sortilin 1 SORT1 6272 NM_001205228 /// NM_002959 /// XM_005271100 /// XM_005271101 /// XM_005271102 /// XM_006710812 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from direct assay /// 0006897 // endocytosis // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0014902 // myotube differentiation // inferred from mutant phenotype /// 0016050 // vesicle organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032509 // endosome transport via multivesicular body sorting pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from mutant phenotype /// 0038180 // nerve growth factor signaling pathway // inferred from direct assay /// 0046323 // glucose import // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0048227 // plasma membrane to endosome transport // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005768 // endosome // non-traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0010465 // nerve growth factor receptor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030379 // neurotensin receptor activity, non-G-protein coupled // inferred from direct assay /// 0048406 // nerve growth factor binding // inferred from physical interaction 212798_s_at AK001389 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001389.1 /DEF=Homo sapiens cDNA FLJ10527 fis, clone NT2RP2000932, highly similar to Homo sapiens mRNA; cDNA DKFZp564O043. /FEA=mRNA /DB_XREF=gi:7022618 /UG=Hs.15144 hypothetical protein DKFZp564O043 AK001389 ankyrin repeat and MYND domain containing 2 ANKMY2 57037 NM_020319 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212799_at BE217875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE217875 /FEA=EST /DB_XREF=gi:8905193 /DB_XREF=est:hv31a03.x1 /CLONE=IMAGE:3174988 /UG=Hs.12311 Homo sapiens clone 23570 mRNA sequence BE217875 syntaxin 6 STX6 10228 NM_001286210 /// NM_005819 /// XM_005244824 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006906 // vesicle fusion // inferred from physical interaction /// 0007032 // endosome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0030136 // clathrin-coated vesicle // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 212800_at AI740832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI740832 /FEA=EST /DB_XREF=gi:5109120 /DB_XREF=est:wg24g02.x1 /CLONE=IMAGE:2366066 /UG=Hs.12311 Homo sapiens clone 23570 mRNA sequence AI740832 syntaxin 6 STX6 10228 NM_001286210 /// NM_005819 /// XM_005244824 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006906 // vesicle fusion // inferred from physical interaction /// 0007032 // endosome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0030136 // clathrin-coated vesicle // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 212801_at AI861788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI861788 /FEA=EST /DB_XREF=gi:5525907 /DB_XREF=est:tz91d04.x1 /CLONE=IMAGE:2295943 /UG=Hs.15767 citron (rho-interacting, serinethreonine kinase 21) AI861788 citron rho-interacting serine/threonine kinase /// microRNA 1178 CIT /// MIR1178 11113 /// 100302274 NM_001206999 /// NM_007174 /// NR_031589 /// XM_005253829 /// XM_006719206 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031985 // Golgi cisterna // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212802_s_at AK023841 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023841.1 /DEF=Homo sapiens cDNA FLJ13779 fis, clone PLACE4000445, highly similar to Homo sapiens mRNA; cDNA DKFZp434C212 (from clone DKFZp434C212). /FEA=mRNA /DB_XREF=gi:10435900 /UG=Hs.172069 DKFZP434C212 protein AK023841 GTPase activating protein and VPS9 domains 1 GAPVD1 26130 NM_001282679 /// NM_001282680 /// NM_001282681 /// NM_015635 /// XM_005251901 /// XM_005251904 /// XM_006717042 /// XM_006717043 /// XM_006717044 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051223 // regulation of protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from mutant phenotype 212803_at BF337329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF337329 /FEA=EST /DB_XREF=gi:11283448 /DB_XREF=est:602034718F1 /CLONE=IMAGE:4182484 /UG=Hs.159223 NGFI-A binding protein 2 (ERG1 binding protein 2) /FL=gb:U48361.1 gb:NM_005967.1 BF337329 NGFI-A binding protein 2 (EGR1 binding protein 2) NAB2 4665 NM_005967 /// XM_005268894 0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0016480 // negative regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation 212804_s_at AI797397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI797397 /FEA=EST /DB_XREF=gi:5362869 /DB_XREF=est:we87f12.x1 /CLONE=IMAGE:2348111 /UG=Hs.172069 DKFZP434C212 protein AI797397 GTPase activating protein and VPS9 domains 1 GAPVD1 26130 NM_001282679 /// NM_001282680 /// NM_001282681 /// NM_015635 /// XM_005251901 /// XM_005251904 /// XM_006717042 /// XM_006717043 /// XM_006717044 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051223 // regulation of protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from mutant phenotype 212805_at AB002365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002365.1 /DEF=Human mRNA for KIAA0367 gene, partial cds. /FEA=mRNA /GEN=kIAA0367 /DB_XREF=gi:2224674 /UG=Hs.23311 KIAA0367 protein AB002365 prune homolog 2 (Drosophila) PRUNE2 158471 NM_015225 /// NM_138818 /// XM_005251745 /// XM_005251746 /// XM_005251748 /// XM_005251750 /// XM_005251751 /// XM_005251752 /// XM_005251753 /// XM_005251754 /// XM_006716982 /// XM_006716983 /// XM_006716984 /// XM_006716985 /// XM_006716986 /// XM_006716987 /// XR_242571 /// XR_428517 /// XR_428518 0006915 // apoptotic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212806_at AL138349 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL138349 /FEA=EST /DB_XREF=gi:6855030 /DB_XREF=est:DKFZp762I1914_s1 /CLONE=DKFZp762I1914 /UG=Hs.23311 KIAA0367 protein AL138349 prune homolog 2 (Drosophila) PRUNE2 158471 NM_015225 /// NM_138818 /// XM_005251745 /// XM_005251746 /// XM_005251748 /// XM_005251750 /// XM_005251751 /// XM_005251752 /// XM_005251753 /// XM_005251754 /// XM_006716982 /// XM_006716983 /// XM_006716984 /// XM_006716985 /// XM_006716986 /// XM_006716987 /// XR_242571 /// XR_428517 /// XR_428518 0006915 // apoptotic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212807_s_at BF447105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF447105 /FEA=EST /DB_XREF=gi:11512243 /DB_XREF=est:7p49d07.x1 /CLONE=IMAGE:3649189 /UG=Hs.281706 sortilin 1 BF447105 sortilin 1 SORT1 6272 NM_001205228 /// NM_002959 /// XM_005271100 /// XM_005271101 /// XM_005271102 /// XM_006710812 0001503 // ossification // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from direct assay /// 0006897 // endocytosis // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0014902 // myotube differentiation // inferred from mutant phenotype /// 0016050 // vesicle organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032509 // endosome transport via multivesicular body sorting pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from mutant phenotype /// 0038180 // nerve growth factor signaling pathway // inferred from direct assay /// 0046323 // glucose import // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0048227 // plasma membrane to endosome transport // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005768 // endosome // non-traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0010465 // nerve growth factor receptor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030379 // neurotensin receptor activity, non-G-protein coupled // inferred from direct assay /// 0048406 // nerve growth factor binding // inferred from physical interaction 212808_at AI884627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI884627 /FEA=EST /DB_XREF=gi:5589791 /DB_XREF=est:wl59b11.x1 /CLONE=IMAGE:2429181 /UG=Hs.274417 PTD017 protein AI884627 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein NFATC2IP 84901 NM_032815 0001816 // cytokine production // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212809_at AA152202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA152202 /FEA=EST /DB_XREF=gi:1721536 /DB_XREF=est:zl06a03.s1 /CLONE=IMAGE:491500 /UG=Hs.274417 PTD017 protein AA152202 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein NFATC2IP 84901 NM_032815 0001816 // cytokine production // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212810_s_at W72527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W72527 /FEA=EST /DB_XREF=gi:1382184 /DB_XREF=est:zd63a09.s1 /CLONE=IMAGE:345304 /UG=Hs.286049 phosphoserine aminotransferase W72527 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 SLC1A4 6509 NM_001135581 /// NM_001193493 /// NM_003038 /// XM_006712079 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from direct assay /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // traceable author statement /// 0015808 // L-alanine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from direct assay /// 0015824 // proline transport // inferred from direct assay /// 0015825 // L-serine transport // inferred from direct assay /// 0015826 // threonine transport // inferred from direct assay /// 0034589 // hydroxyproline transport // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // non-traceable author statement /// 0035524 // proline transmembrane transport // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005254 // chloride channel activity // inferred from direct assay /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from direct assay /// 0015184 // L-cystine transmembrane transporter activity // inferred from direct assay /// 0015186 // L-glutamine transmembrane transporter activity // traceable author statement /// 0015193 // L-proline transmembrane transporter activity // inferred from direct assay /// 0015194 // L-serine transmembrane transporter activity // inferred from direct assay /// 0015195 // L-threonine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation /// 0034590 // L-hydroxyproline transmembrane transporter activity // inferred from direct assay 212811_x_at AI889380 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI889380 /FEA=EST /DB_XREF=gi:5594544 /DB_XREF=est:wm98e02.x1 /CLONE=IMAGE:2443994 /UG=Hs.286049 phosphoserine aminotransferase AI889380 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 SLC1A4 6509 NM_001135581 /// NM_001193493 /// NM_003038 /// XM_006712079 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from direct assay /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // traceable author statement /// 0015808 // L-alanine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from direct assay /// 0015824 // proline transport // inferred from direct assay /// 0015825 // L-serine transport // inferred from direct assay /// 0015826 // threonine transport // inferred from direct assay /// 0034589 // hydroxyproline transport // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // non-traceable author statement /// 0035524 // proline transmembrane transport // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005254 // chloride channel activity // inferred from direct assay /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from direct assay /// 0015184 // L-cystine transmembrane transporter activity // inferred from direct assay /// 0015186 // L-glutamine transmembrane transporter activity // traceable author statement /// 0015193 // L-proline transmembrane transporter activity // inferred from direct assay /// 0015194 // L-serine transmembrane transporter activity // inferred from direct assay /// 0015195 // L-threonine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation /// 0034590 // L-hydroxyproline transmembrane transporter activity // inferred from direct assay 212812_at AI700633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI700633 /FEA=EST /DB_XREF=gi:4988533 /DB_XREF=est:we38g03.x1 /CLONE=IMAGE:2343412 /UG=Hs.288232 Homo sapiens cDNA: FLJ22642 fis, clone HSI06970 AI700633 serine incorporator 5 SERINC5 256987 NM_001174071 /// NM_001174072 /// NM_178276 /// XM_005248478 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006658 // phosphatidylserine metabolic process // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 212813_at AA149644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA149644 /FEA=EST /DB_XREF=gi:1720445 /DB_XREF=est:zl39d08.s1 /CLONE=IMAGE:504303 /UG=Hs.55016 hypothetical protein FLJ21935 AA149644 junctional adhesion molecule 3 JAM3 83700 NM_001205329 /// NM_032801 0001525 // angiogenesis // inferred from direct assay /// 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0002250 // adaptive immune response // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0090022 // regulation of neutrophil chemotaxis // inferred from direct assay /// 0090138 // regulation of actin cytoskeleton organization by cell-cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0033010 // paranodal junction // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0044291 // cell-cell contact zone // inferred from direct assay 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212814_at AB020635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020635.1 /DEF=Homo sapiens mRNA for KIAA0828 protein, partial cds. /FEA=mRNA /GEN=KIAA0828 /PROD=KIAA0828 protein /DB_XREF=gi:4240144 /UG=Hs.4984 KIAA0828 protein AB020635 adenosylhomocysteinase-like 2 AHCYL2 23382 NM_001130720 /// NM_001130722 /// NM_001130723 /// NM_015328 /// XM_005250237 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 212815_at AA156961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156961 /FEA=EST /DB_XREF=gi:1728621 /DB_XREF=est:zl19h05.s1 /CLONE=IMAGE:502425 /UG=Hs.48295 RNA helicase family AA156961 activating signal cointegrator 1 complex subunit 3 ASCC3 10973 NM_001284271 /// NM_006828 /// NM_022091 /// XM_006715322 0006281 // DNA repair // inferred from electronic annotation /// 0006307 // DNA dealkylation involved in DNA repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212816_s_at BE613178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE613178 /FEA=EST /DB_XREF=gi:9894775 /DB_XREF=est:601452166T1 /CLONE=IMAGE:3855712 /UG=Hs.84152 cystathionine-beta-synthase BE613178 cystathionine-beta-synthase CBS 875 NM_000071 /// NM_001178008 /// NM_001178009 /// XM_006724057 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0006535 // cysteine biosynthetic process from serine // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from direct assay /// 0006565 // L-serine catabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0019343 // cysteine biosynthetic process via cystathionine // inferred from electronic annotation /// 0019344 // cysteine biosynthetic process // inferred from electronic annotation /// 0019346 // transsulfuration // traceable author statement /// 0019448 // L-cysteine catabolic process // inferred from direct assay /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0030823 // regulation of cGMP metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043418 // homocysteine catabolic process // inferred from direct assay /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070814 // hydrogen sulfide biosynthetic process // inferred from direct assay /// 0070814 // hydrogen sulfide biosynthetic process // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004122 // cystathionine beta-synthase activity // inferred from direct assay /// 0004122 // cystathionine beta-synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // inferred from mutant phenotype /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 212817_at AK023253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023253.1 /DEF=Homo sapiens cDNA FLJ13191 fis, clone NT2RP3004262, highly similar to Homo sapiens heat shock protein hsp40-3 mRNA. /FEA=mRNA /DB_XREF=gi:10435102 /UG=Hs.237506 DnaJ (Hsp40) homolog, subfamily B, member 5 AK023253 DnaJ (Hsp40) homolog, subfamily B, member 5 DNAJB5 25822 NM_001135004 /// NM_001135005 /// NM_012266 /// XM_005251428 /// XM_006716751 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 212818_s_at AF055024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055024.1 /DEF=Homo sapiens clone 24763 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005752 /UG=Hs.153489 ASB-1 protein /FL=gb:AF156777.1 gb:NM_016114.1 AF055024 ankyrin repeat and SOCS box containing 1 ASB1 51665 NM_001040445 /// NM_016114 /// XM_005246080 /// XR_241235 /// XR_241236 /// XR_241237 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // non-traceable author statement 0005622 // intracellular // inferred by curator 0005515 // protein binding // inferred from electronic annotation 212819_at AF055024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055024.1 /DEF=Homo sapiens clone 24763 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005752 /UG=Hs.153489 ASB-1 protein /FL=gb:AF156777.1 gb:NM_016114.1 AF055024 ankyrin repeat and SOCS box containing 1 ASB1 51665 NM_001040445 /// NM_016114 /// XM_005246080 /// XR_241235 /// XR_241236 /// XR_241237 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // non-traceable author statement 0005622 // intracellular // inferred by curator 0005515 // protein binding // inferred from electronic annotation 212820_at AB020663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020663.1 /DEF=Homo sapiens mRNA for KIAA0856 protein, partial cds. /FEA=mRNA /GEN=KIAA0856 /PROD=KIAA0856 protein /DB_XREF=gi:4240200 /UG=Hs.13264 KIAA0856 protein AB020663 Dmx-like 2 DMXL2 23312 NM_001174116 /// NM_001174117 /// NM_015263 /// XM_005254255 /// XM_005254256 /// XM_005254257 /// XM_005254258 /// XM_006720446 /// XR_243084 /// XR_243085 0005615 // extracellular space // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay 212821_at AU147160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147160 /FEA=EST /DB_XREF=gi:11008681 /DB_XREF=est:AU147160 /CLONE=HEMBB1002566 /UG=Hs.198037 KIAA0599 protein AU147160 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 PLEKHG3 26030 NM_015549 /// XM_005267511 /// XM_005267512 /// XM_005267513 /// XM_006720106 /// XM_006720107 /// XM_006720108 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 212822_at AA121502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA121502 /FEA=EST /DB_XREF=gi:1679116 /DB_XREF=est:zk88a11.s1 /CLONE=IMAGE:489884 /UG=Hs.10491 KIAA1237 protein AA121502 heart development protein with EGF-like domains 1 HEG1 57493 NM_020733 /// XM_005247666 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0003017 // lymph circulation // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0048845 // venous blood vessel morphogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212823_s_at AI738980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738980 /FEA=EST /DB_XREF=gi:5100961 /DB_XREF=est:wi12g08.x1 /CLONE=IMAGE:2390078 /UG=Hs.198037 KIAA0599 protein AI738980 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 PLEKHG3 26030 NM_015549 /// XM_005267511 /// XM_005267512 /// XM_005267513 /// XM_006720106 /// XM_006720107 /// XM_006720108 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 212824_at U69127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U69127.1 /DEF=Human FUSE binding protein 3 (FBP3) mRNA, partial cds. /FEA=mRNA /GEN=FBP3 /PROD=FUSE binding protein 3 /DB_XREF=gi:1575608 /UG=Hs.153636 far upstream element (FUSE) binding protein 3 U69127 far upstream element (FUSE) binding protein 3 FUBP3 8939 NM_003934 /// XM_005272232 /// XM_006717312 /// XM_006717313 /// XM_006717314 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212825_at AI357401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357401 /FEA=EST /DB_XREF=gi:4109022 /DB_XREF=est:qy13d06.x1 /CLONE=IMAGE:2011883 /UG=Hs.173854 PAX transcription activation domain interacting protein 1 like AI357401 PAX interacting (with transcription-activation domain) protein 1 PAXIP1 22976 NM_007349 /// XM_005249536 /// XM_005249537 /// XM_005249539 /// XM_005249541 0000416 // positive regulation of histone H3-K36 methylation // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0035066 // positive regulation of histone acetylation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0045830 // positive regulation of isotype switching // inferred from sequence or structural similarity /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from sequence or structural similarity /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from mutant phenotype /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060717 // chorion development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0035097 // histone methyltransferase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212826_s_at AI961224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI961224 /FEA=EST /DB_XREF=gi:5753937 /DB_XREF=est:wt15b11.x1 /CLONE=IMAGE:2507517 /UG=Hs.164280 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 AI961224 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 SLC25A6 293 NM_001636 0006112 // energy reserve metabolic process // traceable author statement /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015866 // ADP transport // non-traceable author statement /// 0015867 // ATP transport // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005471 // ATP:ADP antiporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212827_at X17115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X17115.1 /DEF=Human mRNA for IgM heavy chain complete sequence. /FEA=mRNA /DB_XREF=gi:33450 /UG=Hs.302063 immunoglobulin heavy constant mu X17115 immunoglobulin heavy constant mu IGHM 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 212828_at AA191573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA191573 /FEA=EST /DB_XREF=gi:1780272 /DB_XREF=est:zp81b09.s1 /CLONE=IMAGE:626585 /UG=Hs.61289 synaptojanin 2 AA191573 synaptojanin 2 SYNJ2 8871 NM_001178088 /// NM_003898 /// XM_005267197 /// XM_005267198 /// XM_005267199 /// XM_005267200 /// XM_006715591 /// XM_006715592 /// XR_245556 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 212829_at BE878277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE878277 /FEA=EST /DB_XREF=gi:10327053 /DB_XREF=est:601488188F1 /CLONE=IMAGE:3890564 /UG=Hs.57079 Homo sapiens cDNA FLJ13267 fis, clone OVARC1000964 BE878277 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha PIP4K2A 5305 NM_005028 /// XM_006717450 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // non-traceable author statement /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 212830_at W68084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W68084 /FEA=EST /DB_XREF=gi:1376954 /DB_XREF=est:zd42f12.s1 /CLONE=IMAGE:343343 /UG=Hs.5599 EGF-like-domain, multiple 5 W68084 multiple EGF-like-domains 9 MEGF9 1955 NM_001080497 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 212831_at BF110421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110421 /FEA=EST /DB_XREF=gi:10940111 /DB_XREF=est:7n52g03.x1 /CLONE=IMAGE:3568324 /UG=Hs.5599 EGF-like-domain, multiple 5 BF110421 multiple EGF-like-domains 9 MEGF9 1955 NM_001080497 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 212832_s_at AI143124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI143124 /FEA=EST /DB_XREF=gi:3664933 /DB_XREF=est:qb76c12.x1 /CLONE=IMAGE:1706038 /UG=Hs.76989 KIAA0097 gene product AI143124 cytoskeleton associated protein 5 CKAP5 9793 NM_001008938 /// NM_014756 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from mutant phenotype /// 0050658 // RNA transport // inferred from sequence or structural similarity /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004519 // endonuclease activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212833_at M74089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M74089.1 /DEF=Human TB1 gene mRNA, 3 end. /FEA=mRNA /GEN=TB1 /DB_XREF=gi:182400 /UG=Hs.75639 Human TB1 gene mRNA, 3 end M74089 solute carrier family 25, member 46 SLC25A46 91137 NM_138773 /// XM_005272127 0006810 // transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212834_at BE963238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE963238 /FEA=EST /DB_XREF=gi:11766656 /DB_XREF=est:601656862R1 /CLONE=IMAGE:3865887 /UG=Hs.99423 ATP-dependent RNA helicase BE963238 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 DDX52 11056 NM_001291476 /// NM_007010 /// NM_152300 /// XM_006721650 /// XM_006725299 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212835_at AA777641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA777641 /FEA=EST /DB_XREF=gi:2837120 /DB_XREF=est:zi95c06.s1 /CLONE=IMAGE:448522 /UG=Hs.82324 KIAA0157 protein AA777641 family with sequence similarity 175, member B FAM175B 23172 NM_032182 0070552 // BRISC complex // inferred from direct assay 0031593 // polyubiquitin binding // inferred from direct assay 212836_at D26018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D26018.1 /DEF=Human mRNA for KIAA0039 gene, partial cds. /FEA=mRNA /GEN=KIAA0039 /DB_XREF=gi:436221 /UG=Hs.82502 polymerase (DNA directed), delta 3 D26018 polymerase (DNA-directed), delta 3, accessory subunit POLD3 10714 NM_006591 /// NR_046409 /// NR_046410 /// XM_005273716 /// XR_428902 /// XR_428903 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // non-traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // non-traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043625 // delta DNA polymerase complex // non-traceable author statement 0003887 // DNA-directed DNA polymerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 212837_at D63877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D63877.1 /DEF=Human mRNA for KIAA0157 gene, partial cds. /FEA=mRNA /GEN=KIAA0157 /DB_XREF=gi:961445 /UG=Hs.82324 KIAA0157 protein D63877 family with sequence similarity 175, member B FAM175B 23172 NM_032182 0070552 // BRISC complex // inferred from direct assay 0031593 // polyubiquitin binding // inferred from direct assay 212838_at AB023227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023227.1 /DEF=Homo sapiens mRNA for KIAA1010 protein, partial cds. /FEA=mRNA /GEN=KIAA1010 /PROD=KIAA1010 protein /DB_XREF=gi:4589669 /UG=Hs.23860 KIAA1010 protein AB023227 dynamin binding protein DNMBP 23268 NM_015221 /// XM_006717735 /// XM_006717736 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212839_s_at AK024044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024044.1 /DEF=Homo sapiens cDNA FLJ13982 fis, clone Y79AA1001711, highly similar to Human 60-kdal ribonucleoprotein (Ro) mRNA. /FEA=mRNA /DB_XREF=gi:10436311 /UG=Hs.554 Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) AK024044 TROVE domain family, member 2 TROVE2 6738 NM_001042369 /// NM_001042370 /// NM_001173524 /// NM_001173525 /// NM_004600 /// NR_033393 /// XM_006711495 /// XM_006711496 /// XM_006711497 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212840_at BG339560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG339560 /FEA=EST /DB_XREF=gi:13145998 /DB_XREF=est:602437413F1 /CLONE=IMAGE:4555466 /UG=Hs.127287 KIAA0794 protein BG339560 UBX domain protein 7 UBXN7 26043 NM_015562 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 212841_s_at AI692180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI692180 /FEA=EST /DB_XREF=gi:4969520 /DB_XREF=est:wd37f06.x1 /CLONE=IMAGE:2330339 /UG=Hs.12953 PTPRF interacting protein, binding protein 2 (liprin beta 2) AI692180 PTPRF interacting protein, binding protein 2 (liprin beta 2) PPFIBP2 8495 NM_001256568 /// NM_001256569 /// NM_003621 /// XM_005253174 /// XM_005253175 /// XM_005253176 /// XM_005253177 /// XM_006718349 /// XM_006718350 /// XM_006718351 /// XM_006718352 /// XM_006718353 0007154 // cell communication // non-traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 212842_x_at AL043571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043571 /FEA=EST /DB_XREF=gi:5422958 /DB_XREF=est:DKFZp434F1527_s1 /CLONE=DKFZp434F1527 /UG=Hs.179825 RAN binding protein 2-like 1 AL043571 RANBP2-like and GRIP domain containing 3 /// RANBP2-like and GRIP domain containing 4 /// RANBP2-like and GRIP domain containing 5 /// RANBP2-like and GRIP domain containing 6 /// RANBP2-like and GRIP domain containing 8 RGPD3 /// RGPD4 /// RGPD5 /// RGPD6 /// RGPD8 84220 /// 285190 /// 653489 /// 727851 /// 729540 NM_001037866 /// NM_001123363 /// NM_001144013 /// NM_001164463 /// NM_005054 /// NM_032260 /// NM_182588 /// XM_005263747 /// XM_005263748 /// XM_005263753 /// XM_005263755 /// XM_005263756 /// XM_005263819 /// XM_005263820 /// XM_005263821 /// XM_005263822 /// XM_006712454 /// XM_006712708 /// XM_006712794 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // non-traceable author statement 212843_at AA126505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA126505 /FEA=EST /DB_XREF=gi:1686153 /DB_XREF=est:zn86a09.s1 /CLONE=IMAGE:565048 /UG=Hs.167988 neural cell adhesion molecule 1 AA126505 neural cell adhesion molecule 1 NCAM1 4684 NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351 0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 212844_at AI400490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI400490 /FEA=EST /DB_XREF=gi:4243577 /DB_XREF=est:tg90b07.x1 /CLONE=IMAGE:2116021 /UG=Hs.152629 KIAA0179 protein AI400490 ribosomal RNA processing 1B RRP1B 23076 NM_015056 0006364 // rRNA processing // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0000791 // euchromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030688 // preribosome, small subunit precursor // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212845_at AB028976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028976.1 /DEF=Homo sapiens mRNA for KIAA1053 protein, partial cds. /FEA=mRNA /GEN=KIAA1053 /PROD=KIAA1053 protein /DB_XREF=gi:5689442 /UG=Hs.173571 KIAA1053 protein AB028976 sterile alpha motif domain containing 4A SAMD4A 23034 NM_001161576 /// NM_001161577 /// NM_015589 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030371 // translation repressor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 212846_at AA811192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA811192 /FEA=EST /DB_XREF=gi:2880803 /DB_XREF=est:ob72b08.s1 /CLONE=IMAGE:1336887 /UG=Hs.152629 KIAA0179 protein AA811192 ribosomal RNA processing 1B RRP1B 23076 NM_015056 0006364 // rRNA processing // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0000791 // euchromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030688 // preribosome, small subunit precursor // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212847_at AL036840 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL036840 /FEA=EST /DB_XREF=gi:5406335 /DB_XREF=est:DKFZp564N1963_s1 /CLONE=DKFZp564N1963 /UG=Hs.22370 Homo sapiens mRNA; cDNA DKFZp564O0122 (from clone DKFZp564O0122) AL036840 far upstream element (FUSE) binding protein 1 FUBP1 8880 NM_003902 /// XM_005271309 /// XM_006711021 /// XM_006711022 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212848_s_at BG036668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG036668 /FEA=EST /DB_XREF=gi:12432092 /DB_XREF=est:602326882F1 /CLONE=IMAGE:4428237 /UG=Hs.18075 chromosome 9 open reading frame 3 BG036668 chromosome 9 open reading frame 3 C9orf3 84909 NM_001193329 /// NM_001193330 /// NM_001193331 /// NM_032823 /// XM_005252284 /// XM_006717306 /// XM_006717307 0006508 // proteolysis // inferred from direct assay /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004177 // aminopeptidase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212849_at AA745954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA745954 /FEA=EST /DB_XREF=gi:2785940 /DB_XREF=est:ob18e04.s1 /CLONE=IMAGE:1324062 /UG=Hs.184434 axin AA745954 axin 1 AXIN1 8312 NM_003502 /// NM_181050 /// XM_005255607 /// XM_005255608 /// XM_005255609 /// XM_005255610 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001743 // optic placode formation // not recorded /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // not recorded /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008219 // cell death // not recorded /// 0009950 // dorsal/ventral axis specification // not recorded /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021797 // forebrain anterior/posterior pattern specification // not recorded /// 0021881 // Wnt-activated signaling pathway involved in forebrain neuron fate commitment // not recorded /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030910 // olfactory placode formation // not recorded /// 0031122 // cytoplasmic microtubule organization // not recorded /// 0031398 // positive regulation of protein ubiquitination // non-traceable author statement /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // non-traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // not recorded /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // not recorded /// 0048318 // axial mesoderm development // inferred from electronic annotation /// 0048320 // axial mesoderm formation // not recorded /// 0051248 // negative regulation of protein metabolic process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0055001 // muscle cell development // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060272 // embryonic skeletal joint morphogenesis // not recorded /// 0060823 // canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation // not recorded /// 0071407 // cellular response to organic cyclic compound // not recorded /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // not recorded /// 0090244 // Wnt signaling pathway involved in somitogenesis // not recorded /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005881 // cytoplasmic microtubule // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // not recorded /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from direct assay /// 0005096 // GTPase activator activity // not recorded /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043621 // protein self-association // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // not recorded /// 0070016 // armadillo repeat domain binding // inferred from sequence or structural similarity /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from electronic annotation 212850_s_at AA584297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA584297 /FEA=EST /DB_XREF=gi:2368906 /DB_XREF=est:nn79e08.s1 /CLONE=IMAGE:1090118 /UG=Hs.4930 low density lipoprotein receptor-related protein 4 AA584297 low density lipoprotein receptor-related protein 4 LRP4 4038 NM_002334 /// XM_005252923 /// XM_006718231 0001822 // kidney development // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0051124 // synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0051290 // protein heterotetramerization // inferred from sequence or structural similarity /// 0060173 // limb development // inferred from direct assay /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 1901631 // positive regulation of presynaptic membrane organization // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 212851_at AA194584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA194584 /FEA=EST /DB_XREF=gi:1784345 /DB_XREF=est:zq06f03.s1 /CLONE=IMAGE:628925 /UG=Hs.240112 KIAA0276 protein AA194584 DCN1, defective in cullin neddylation 1, domain containing 4 DCUN1D4 23142 NM_001040402 /// NM_001287755 /// NM_001287757 /// NM_015115 /// XM_005265731 /// XM_005265732 /// XM_005265733 /// XM_005265734 /// XR_245254 /// XR_427521 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212852_s_at AL538601 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL538601 /FEA=EST /DB_XREF=gi:12867040 /DB_XREF=est:AL538601 /CLONE=CS0DF024YB05 (5 prime) /UG=Hs.554 Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) AL538601 TROVE domain family, member 2 TROVE2 6738 NM_001042369 /// NM_001042370 /// NM_001173524 /// NM_001173525 /// NM_004600 /// NR_033393 /// XM_006711495 /// XM_006711496 /// XM_006711497 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212853_at AA779297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA779297 /FEA=EST /DB_XREF=gi:2838628 /DB_XREF=est:zj43h11.s1 /CLONE=IMAGE:453093 /UG=Hs.240112 KIAA0276 protein AA779297 DCN1, defective in cullin neddylation 1, domain containing 4 DCUN1D4 23142 NM_001040402 /// NM_001287755 /// NM_001287757 /// NM_015115 /// XM_005265731 /// XM_005265732 /// XM_005265733 /// XM_005265734 /// XR_245254 /// XR_427521 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212854_x_at AB051480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051480.1 /DEF=Homo sapiens mRNA for KIAA1693 protein, partial cds. /FEA=mRNA /GEN=KIAA1693 /PROD=KIAA1693 protein /DB_XREF=gi:12697930 /UG=Hs.323463 KIAA1693 protein; hypothetical protein FLJ20719 AB051480 neuroblastoma breakpoint family, member 1 NBPF1 55672 NM_017940 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 212855_at D87466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87466.1 /DEF=Human mRNA for KIAA0276 gene, partial cds. /FEA=mRNA /GEN=KIAA0276 /DB_XREF=gi:1665816 /UG=Hs.240112 KIAA0276 protein D87466 DCN1, defective in cullin neddylation 1, domain containing 4 DCUN1D4 23142 NM_001040402 /// NM_001287755 /// NM_001287757 /// NM_015115 /// XM_005265731 /// XM_005265732 /// XM_005265733 /// XM_005265734 /// XR_245254 /// XR_427521 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212856_at AB018310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018310.1 /DEF=Homo sapiens mRNA for KIAA0767 protein, partial cds. /FEA=mRNA /GEN=KIAA0767 /PROD=KIAA0767 protein /DB_XREF=gi:3882254 /UG=Hs.95180 KIAA0767 protein AB018310 GRAM domain containing 4 GRAMD4 23151 NM_015124 /// XM_005261396 /// XM_005261397 /// XM_005261398 /// XM_005261399 /// XM_005261400 /// XM_006724168 /// XM_006724169 /// XM_006724170 0006915 // apoptotic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 212857_x_at BG231551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG231551 /FEA=EST /DB_XREF=gi:12726658 /DB_XREF=est:naf29h05.x1 /CLONE=IMAGE:4142457 /UG=Hs.74861 activated RNA polymerase II transcription cofactor 4 BG231551 SUB1 homolog (S. cerevisiae) SUB1 10923 NM_006713 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212858_at AL520675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL520675 /FEA=EST /DB_XREF=gi:12784168 /DB_XREF=est:AL520675 /CLONE=CS0DB002YF15 (3 prime) /UG=Hs.77783 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase AL520675 progestin and adipoQ receptor family member IV PAQR4 124222 NM_001284511 /// NM_001284512 /// NM_001284513 /// NM_152341 /// XM_005255112 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded 212859_x_at BF217861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF217861 /FEA=EST /DB_XREF=gi:11111447 /DB_XREF=est:601885414F1 /CLONE=IMAGE:4103955 /UG=Hs.74170 metallothionein 1E (functional) BF217861 metallothionein 1E MT1E 4493 NM_175617 /// XM_005255956 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212860_at BG168720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG168720 /FEA=EST /DB_XREF=gi:12675423 /DB_XREF=est:602319986F1 /CLONE=IMAGE:4415372 /UG=Hs.19066 Homo sapiens mRNA; cDNA DKFZp667O2416 (from clone DKFZp667O2416) BG168720 zinc finger, DHHC-type containing 18 ZDHHC18 84243 NM_032283 0008152 // metabolic process // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212861_at BF690150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF690150 /FEA=EST /DB_XREF=gi:11975558 /DB_XREF=est:602186478T1 /CLONE=IMAGE:4298635 /UG=Hs.19210 ESTs BF690150 major facilitator superfamily domain containing 5 MFSD5 84975 NM_001170790 /// NM_032889 /// XM_005269197 /// XM_005269198 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212862_at AL568982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568982 /FEA=EST /DB_XREF=gi:12923866 /DB_XREF=est:AL568982 /CLONE=CS0DE003YG20 (3 prime) /UG=Hs.24812 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 AL568982 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 CDS2 8760 NM_003818 /// XM_006723660 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004605 // phosphatidate cytidylyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 212863_x_at BF337195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF337195 /FEA=EST /DB_XREF=gi:11283540 /DB_XREF=est:602034795F1 /CLONE=IMAGE:4182742 /UG=Hs.239737 C-terminal binding protein 1 BF337195 C-terminal binding protein 1 CTBP1 1487 NM_001012614 /// NM_001328 /// XM_005272261 /// XM_005272262 /// XM_005272263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007030 // Golgi organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from mutant phenotype /// 0034401 // regulation of transcription by chromatin organization // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090241 // negative regulation of histone H4 acetylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 212864_at Y16521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y16521.1 /DEF=Homo sapiens mRNA for CDS2 protein. /FEA=mRNA /GEN=cds2 /PROD=CDS2 protein /DB_XREF=gi:4186022 /UG=Hs.24812 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 Y16521 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 CDS2 8760 NM_003818 /// XM_006723660 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004605 // phosphatidate cytidylyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 212865_s_at BF449063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF449063 /FEA=EST /DB_XREF=gi:11515232 /DB_XREF=est:7o64f12.x1 /CLONE=IMAGE:3579023 /UG=Hs.36131 collagen, type XIV, alpha 1 (undulin) BF449063 collagen, type XIV, alpha 1 COL14A1 7373 NM_021110 /// XM_005251059 /// XM_006716651 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0061050 // regulation of cell growth involved in cardiac muscle cell development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // non-traceable author statement /// 0005596 // collagen type XIV trimer // non-traceable author statement /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 212866_at AI081543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI081543 /FEA=EST /DB_XREF=gi:3418335 /DB_XREF=est:on04g12.x1 /CLONE=IMAGE:1555750 /UG=Hs.300861 ESTs, Highly similar to T08701 hypothetical protein DKFZp564N123.1 H.sapiens AI081543 R3H domain and coiled-coil containing 1 R3HCC1 203069 NM_001136108 /// XM_005273427 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation 212867_at AI040324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040324 /FEA=EST /DB_XREF=gi:3279518 /DB_XREF=est:oy33a12.x1 /CLONE=IMAGE:1667614 /UG=Hs.29131 nuclear receptor coactivator 2 AI040324 nuclear receptor coactivator 2 NCOA2 10499 NM_006540 /// XM_005251128 /// XM_005251129 /// XM_005251130 /// XM_005251131 /// XM_005251132 /// XM_005251133 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from reviewed computational analysis /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 212868_x_at NM_003668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003668.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mRNA. /FEA=CDS /GEN=MAPKAPK5 /PROD=mitogen-activated protein kinase-activatedprotein kinase 5 /DB_XREF=gi:4506034 /UG=Hs.30327 mitogen-activated protein kinase-activated protein kinase 5 /FL=gb:NM_003668.1 NM_003668 MAPKAPK5 antisense RNA 1 MAPKAPK5-AS1 51275 NM_016534 /// NR_015404 212869_x_at AI721229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI721229 /FEA=EST /DB_XREF=gi:5038485 /DB_XREF=est:as68c10.x1 /CLONE=IMAGE:2333874 /UG=Hs.326456 hypothetical protein FLJ20030 AI721229 uncharacterized LOC101928826 /// tumor protein, translationally-controlled 1 LOC101928826 /// TPT1 7178 /// 101928826 NM_001286272 /// NM_001286273 /// NM_003295 /// XR_242670 /// XR_250536 /// XR_252641 0006816 // calcium ion transport // inferred by curator /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0009615 // response to virus // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000384 // negative regulation of ectoderm development // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005771 // multivesicular body // inferred from direct assay /// 0045298 // tubulin complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212870_at AI628605 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI628605 /FEA=EST /DB_XREF=gi:4665405 /DB_XREF=est:ty77a08.x1 /CLONE=IMAGE:2285078 /UG=Hs.326392 son of sevenless (Drosophila) homolog 1 /FL=gb:L13858.1 gb:NM_005633.1 AI628605 son of sevenless homolog 2 (Drosophila) SOS2 6655 NM_006939 /// XM_005268021 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212871_at NM_003668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003668.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mRNA. /FEA=CDS /GEN=MAPKAPK5 /PROD=mitogen-activated protein kinase-activatedprotein kinase 5 /DB_XREF=gi:4506034 /UG=Hs.30327 mitogen-activated protein kinase-activated protein kinase 5 /FL=gb:NM_003668.1 NM_003668 mitogen-activated protein kinase-activated protein kinase 5 MAPKAPK5 8550 NM_003668 /// NM_139078 /// XM_005253974 /// XM_005253975 /// XM_005253976 /// XM_005253977 /// XM_005253978 /// XM_005253979 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0090400 // stress-induced premature senescence // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 212872_s_at AK023092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023092.1 /DEF=Homo sapiens cDNA FLJ13030 fis, clone NT2RP3001111, highly similar to Homo sapiens TRF-proximal protein mRNA. /FEA=mRNA /DB_XREF=gi:10434851 /UG=Hs.93796 DKFZP586D2223 protein AK023092 mediator complex subunit 20 MED20 9477 NM_004275 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // non-traceable author statement 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212873_at BE349017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE349017 /FEA=EST /DB_XREF=gi:9260870 /DB_XREF=est:ht48a03.x1 /CLONE=IMAGE:3149932 /UG=Hs.196914 minor histocompatibility antigen HA-1 BE349017 histocompatibility (minor) HA-1 HMHA1 23526 NM_001258328 /// NM_001282334 /// NM_001282335 /// NM_012292 /// XM_006722713 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212874_at AI358867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI358867 /FEA=EST /DB_XREF=gi:4110488 /DB_XREF=est:qy24a09.x1 /CLONE=IMAGE:2012920 /UG=Hs.169401 apolipoprotein E AI358867 212875_s_at AP001745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AP001745 /DEF=Homo sapiens genomic DNA, chromosome 21q, section 89105 /FEA=mRNA_3 /DB_XREF=gi:7768737 /UG=Hs.16007 chromosome 21 open reading frame 25 AP001745 C2 calcium-dependent domain containing 2 C2CD2 25966 NM_015500 /// NM_199050 /// XM_005261106 /// XM_005261107 /// XM_005261109 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 212876_at BF223021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223021 /FEA=EST /DB_XREF=gi:11130198 /DB_XREF=est:7q27f07.x1 /CLONE=IMAGE:3699612 /UG=Hs.13225 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 /FL=gb:AF022367.1 gb:AB024436.1 BF223021 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 B4GALT4 8702 NM_003778 /// NM_212543 /// XM_005247855 /// XM_005247857 /// XM_006713798 /// XM_006713799 /// XM_006713800 /// XM_006713801 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006643 // membrane lipid metabolic process // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003945 // N-acetyllactosamine synthase activity // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212877_at AA284075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284075 /FEA=EST /DB_XREF=gi:1928356 /DB_XREF=est:zs49b01.s1 /CLONE=IMAGE:700777 /UG=Hs.117977 kinesin 2 (60-70kD) AA284075 kinesin light chain 1 KLC1 3831 NM_001130107 /// NM_005552 /// NM_182923 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from electronic annotation 212878_s_at AA284075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284075 /FEA=EST /DB_XREF=gi:1928356 /DB_XREF=est:zs49b01.s1 /CLONE=IMAGE:700777 /UG=Hs.117977 kinesin 2 (60-70kD) AA284075 kinesin light chain 1 KLC1 3831 NM_001130107 /// NM_005552 /// NM_182923 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from electronic annotation 212879_x_at NM_015897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_015897.1 /DEF=Homo sapiens protein inhibitor of activated STAT protein PIASy (PIASY), mRNA. /FEA=CDS /GEN=PIASY /PROD=protein inhibitor of activated STAT proteinPIASy /DB_XREF=gi:7706229 /UG=Hs.105779 protein inhibitor of activated STAT protein PIASy /FL=gb:AF077952.1 gb:AF164437.1 gb:NM_015897.1 gb:NM_016149.1 NM_015897 protein inhibitor of activated STAT, 4 PIAS4 51588 NM_015897 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from sequence or structural similarity /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019789 // SUMO ligase activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212880_at AB011113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011113.1 /DEF=Homo sapiens mRNA for KIAA0541 protein, partial cds. /FEA=mRNA /GEN=KIAA0541 /PROD=KIAA0541 protein /DB_XREF=gi:3043605 /UG=Hs.10881 WD repeat domain 7 AB011113 WD repeat domain 7 WDR7 23335 NM_015285 /// NM_052834 /// XM_005266674 /// XM_006722431 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212881_at AK022481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022481.1 /DEF=Homo sapiens cDNA FLJ12419 fis, clone MAMMA1003047, highly similar to Homo sapiens protein inhibitor of activated STAT protein PIASy mRNA. /FEA=mRNA /DB_XREF=gi:10433892 /UG=Hs.105779 protein inhibitor of activated STAT protein PIASy /FL=gb:AF077952.1 gb:AF164437.1 gb:NM_015897.1 gb:NM_016149.1 AK022481 protein inhibitor of activated STAT, 4 PIAS4 51588 NM_015897 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from sequence or structural similarity /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019789 // SUMO ligase activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212882_at AB018338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018338.1 /DEF=Homo sapiens mRNA for KIAA0795 protein, partial cds. /FEA=mRNA /GEN=KIAA0795 /PROD=KIAA0795 protein /DB_XREF=gi:3882310 /UG=Hs.22926 KIAA0795 protein AB018338 kelch-like family member 18 KLHL18 23276 NM_025010 /// XM_005265001 /// XM_005265002 /// XM_005265003 /// XM_006713079 0005515 // protein binding // inferred from electronic annotation 212883_at AI358867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI358867 /FEA=EST /DB_XREF=gi:4110488 /DB_XREF=est:qy24a09.x1 /CLONE=IMAGE:2012920 /UG=Hs.169401 apolipoprotein E AI358867 212884_x_at AI358867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI358867 /FEA=EST /DB_XREF=gi:4110488 /DB_XREF=est:qy24a09.x1 /CLONE=IMAGE:2012920 /UG=Hs.169401 apolipoprotein E AI358867 apolipoprotein E APOE 348 NM_000041 /// XM_005258867 0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0010900 // negative regulation of phosphatidylcholine catabolic process // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032374 // regulation of cholesterol transport // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034369 // plasma lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // traceable author statement /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 212885_at AL545921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL545921 /FEA=EST /DB_XREF=gi:12878555 /DB_XREF=est:AL545921 /CLONE=CS0DI023YF24 (3 prime) /UG=Hs.201676 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) AL545921 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) MPHOSPH10 10199 NM_005791 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0008380 // RNA splicing // non-traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // non-traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212886_at AL080169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080169.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C171 (from clone DKFZp434C171); partial cds. /FEA=mRNA /GEN=DKFZp434C171 /PROD=hypothetical protein /DB_XREF=gi:5262637 /UG=Hs.209100 DKFZP434C171 protein AL080169 coiled-coil domain containing 69 CCDC69 26112 NM_015621 0005783 // endoplasmic reticulum // inferred from electronic annotation 212887_at AI753659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI753659 /FEA=EST /DB_XREF=gi:5131923 /DB_XREF=est:cr13e03.x1 /CLONE=HBMSC_cr13e03 /UG=Hs.321403 Homo sapiens mRNA; cDNA DKFZp564O2363 (from clone DKFZp564O2363) AI753659 Sec23 homolog A (S. cerevisiae) SEC23A 10484 NM_006364 /// XM_005267262 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0030868 // smooth endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 212888_at BG109746 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG109746 /FEA=EST /DB_XREF=gi:12603252 /DB_XREF=est:602280883F1 /CLONE=IMAGE:4368381 /UG=Hs.325625 Homo sapiens clone 23938 mRNA sequence BG109746 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212889_x_at BF303939 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF303939 /FEA=EST /DB_XREF=gi:11250616 /DB_XREF=est:601886572F2 /CLONE=IMAGE:4120576 /UG=Hs.83135 Homo sapiens, Similar to RIKEN cDNA 2310040G17 gene, clone IMAGE:3615328, mRNA, partial cds BF303939 growth arrest and DNA-damage-inducible, gamma interacting protein 1 GADD45GIP1 90480 NM_052850 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212890_at BF663461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF663461 /FEA=EST /DB_XREF=gi:11937356 /DB_XREF=est:602144623F1 /CLONE=IMAGE:4297924 /UG=Hs.332158 Homo sapiens clone PP1744 unknown mRNA BF663461 solute carrier family 38, member 10 SLC38A10 124565 NM_001037984 /// NM_138570 /// XM_005257019 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212891_s_at BF972185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF972185 /FEA=EST /DB_XREF=gi:12339400 /DB_XREF=est:602240836F1 /CLONE=IMAGE:4329272 /UG=Hs.83135 Homo sapiens, Similar to RIKEN cDNA 2310040G17 gene, clone IMAGE:3615328, mRNA, partial cds BF972185 growth arrest and DNA-damage-inducible, gamma interacting protein 1 GADD45GIP1 90480 NM_052850 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212892_at AW130128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW130128 /FEA=EST /DB_XREF=gi:6131733 /DB_XREF=est:xf28f07.x1 /CLONE=IMAGE:2619397 /UG=Hs.58167 zinc finger protein 282 AW130128 zinc finger protein 282 ZNF282 8427 NM_003575 /// XM_006716151 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 212893_at AL080063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080063.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I052 (from clone DKFZp564I052). /FEA=mRNA /GEN=DKFZp564I052 /PROD=hypothetical protein /DB_XREF=gi:5262468 /UG=Hs.5364 DKFZP564I052 protein AL080063 zinc finger, ZZ-type containing 3 ZZZ3 26009 NM_015534 /// XM_005270725 /// XM_005270726 /// XM_005270727 /// XM_005270728 /// XM_005270729 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212894_at NM_003171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003171.1 /DEF=Homo sapiens suppressor of var1 (S.cerevisiae) 3-like 1 (SUPV3L1), mRNA. /FEA=CDS /GEN=SUPV3L1 /PROD=suppressor of var1 (S.cerevisiae) 3-like 1 /DB_XREF=gi:4507314 /UG=Hs.106469 suppressor of var1 (S.cerevisiae) 3-like 1 /FL=gb:AF042169.1 gb:NM_003171.1 NM_003171 suppressor of var1, 3-like 1 (S. cerevisiae) SUPV3L1 6832 NM_003171 /// XM_005270068 0000958 // mitochondrial mRNA catabolic process // inferred from mutant phenotype /// 0000962 // positive regulation of mitochondrial RNA catabolic process // inferred from direct assay /// 0000962 // positive regulation of mitochondrial RNA catabolic process // inferred from mutant phenotype /// 0000965 // mitochondrial RNA 3'-end processing // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006310 // DNA recombination // inferred from mutant phenotype /// 0006401 // RNA catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0035945 // mitochondrial ncRNA surveillance // inferred from mutant phenotype /// 0035946 // mitochondrial mRNA surveillance // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0070827 // chromatin maintenance // inferred from mutant phenotype /// 2000827 // mitochondrial RNA surveillance // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0045025 // mitochondrial degradosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003678 // DNA helicase activity // inferred from mutant phenotype /// 0003723 // RNA binding // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0034458 // 3'-5' RNA helicase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212895_s_at AL527773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL527773 /FEA=EST /DB_XREF=gi:12791266 /DB_XREF=est:AL527773 /CLONE=CS0DC026YF10 (3 prime) /UG=Hs.118021 active BCR-related gene AL527773 active BCR-related ABR 29 NM_001092 /// NM_001159746 /// NM_001256847 /// NM_001282149 /// NM_021962 /// XM_006721506 /// XM_006721507 /// XM_006721508 /// XM_006721509 /// XM_006721510 /// XM_006721511 /// XM_006721512 /// XM_006725292 /// XM_006725293 /// XM_006725294 /// XM_006725295 /// XM_006725296 /// XM_006725297 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043314 // negative regulation of neutrophil degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 212896_at D29641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D29641.2 /DEF=Homo sapiens mRNA for KIAA0052 protein, partial cds. /FEA=mRNA /GEN=KIAA0052 /PROD=KIAA0052 protein /DB_XREF=gi:6633994 /UG=Hs.278608 KIAA0052 protein D29641 superkiller viralicidic activity 2-like 2 (S. cerevisiae) SKIV2L2 23517 NM_015360 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212897_at AI738802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738802 /FEA=EST /DB_XREF=gi:5100783 /DB_XREF=est:wi36g07.x1 /CLONE=IMAGE:2392380 /UG=Hs.129836 KIAA1028 protein AI738802 cyclin-dependent kinase 19 CDK19 23097 NM_015076 /// XM_005266870 /// XM_005266871 /// XM_005266872 /// XM_005266873 /// XM_006715402 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212898_at AB007866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007866.2 /DEF=Homo sapiens mRNA for KIAA0406 protein, partial cds. /FEA=mRNA /GEN=KIAA0406 /PROD=KIAA0406 protein /DB_XREF=gi:6634030 /UG=Hs.158249 KIAA0406 gene product AB007866 TELO2 interacting protein 1 TTI1 9675 NM_014657 /// XM_005260621 /// XR_244159 /// XR_244160 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0031931 // TORC1 complex // inferred from direct assay /// 0031932 // TORC2 complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212899_at AB028951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028951.1 /DEF=Homo sapiens mRNA for KIAA1028 protein, partial cds. /FEA=mRNA /GEN=KIAA1028 /PROD=KIAA1028 protein /DB_XREF=gi:5689392 /UG=Hs.129836 KIAA1028 protein AB028951 cyclin-dependent kinase 19 CDK19 23097 NM_015076 /// XM_005266870 /// XM_005266871 /// XM_005266872 /// XM_005266873 /// XM_006715402 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212900_at AJ131244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ131244.1 /DEF=Homo sapiens mRNA for Sec24 protein (Sec24A isoform), partial. /FEA=mRNA /PROD=Sec24A protein /DB_XREF=gi:3947687 /UG=Hs.211612 SEC24 (S. cerevisiae) related gene family, member A AJ131244 SEC24 family member A SEC24A 10802 NM_001252231 /// NM_021982 /// XM_005271854 /// XM_006714523 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 212901_s_at BF732638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF732638 /FEA=EST /DB_XREF=gi:12057713 /DB_XREF=est:nae13f03.x1 /CLONE=IMAGE:3435388 /UG=Hs.21992 likely ortholog of mouse variant polyadenylation protein CSTF-64; KIAA0689 protein BF732638 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant CSTF2T 23283 NM_015235 0006397 // mRNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212902_at BE645231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645231 /FEA=EST /DB_XREF=gi:9969542 /DB_XREF=est:7e66g08.x1 /CLONE=IMAGE:3287486 /UG=Hs.211612 SEC24 (S. cerevisiae) related gene family, member A BE645231 SEC24 family member A SEC24A 10802 NM_001252231 /// NM_021982 /// XM_005271854 /// XM_006714523 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 212904_at AB033011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033011.1 /DEF=Homo sapiens mRNA for KIAA1185 protein, partial cds. /FEA=mRNA /GEN=KIAA1185 /PROD=KIAA1185 protein /DB_XREF=gi:6330301 /UG=Hs.268488 KIAA1185 protein AB033011 leucine rich repeat containing 47 LRRC47 57470 NM_020710 0008152 // metabolic process // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212905_at AI872408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI872408 /FEA=EST /DB_XREF=gi:5546457 /DB_XREF=est:wm58f02.x1 /CLONE=IMAGE:2440155 /UG=Hs.21992 likely ortholog of mouse variant polyadenylation protein CSTF-64; KIAA0689 protein AI872408 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant CSTF2T 23283 NM_015235 0006397 // mRNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212906_at BE044440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE044440 /FEA=EST /DB_XREF=gi:8361493 /DB_XREF=est:ho45e07.x1 /CLONE=IMAGE:3040356 /UG=Hs.251278 KIAA1201 protein BE044440 GRAM domain containing 1B GRAMD1B 57476 NM_001286563 /// NM_001286564 /// NM_020716 /// XM_005271619 /// XM_005271621 /// XM_005271622 /// XM_005271623 /// XM_005271624 /// XM_006718887 /// XM_006718888 /// XM_006718889 /// XM_006718890 /// XM_006718891 /// XM_006718892 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212907_at AI972416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI972416 /FEA=EST /DB_XREF=gi:5769332 /DB_XREF=est:wr39d10.x1 /CLONE=IMAGE:2490067 /UG=Hs.24385 Human hbc647 mRNA sequence AI972416 solute carrier family 30 (zinc transporter), member 1 SLC30A1 7779 NM_021194 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006882 // cellular zinc ion homeostasis // inferred from sequence or structural similarity /// 0046929 // negative regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070509 // calcium ion import // inferred from electronic annotation /// 0070574 // cadmium ion transmembrane transport // inferred from sequence or structural similarity /// 0071577 // zinc ion transmembrane transport // inferred from electronic annotation /// 0071584 // negative regulation of zinc ion transmembrane import // inferred from sequence or structural similarity /// 0071585 // detoxification of cadmium ion // inferred from electronic annotation /// 0090281 // negative regulation of calcium ion import // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from sequence or structural similarity 212908_at AK022530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022530.1 /DEF=Homo sapiens cDNA FLJ12468 fis, clone NT2RM1000857, highly similar to Homo sapiens mRNA for KIAA0962 protein. /FEA=mRNA /DB_XREF=gi:10433971 /UG=Hs.9059 KIAA0962 protein AK022530 DnaJ (Hsp40) homolog, subfamily C, member 16 DNAJC16 23341 NM_001287811 /// NM_015291 /// NR_109898 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212909_at AL567376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567376 /FEA=EST /DB_XREF=gi:12920672 /DB_XREF=est:AL567376 /CLONE=CS0DF024YO04 (3 prime) /UG=Hs.85339 G protein-coupled receptor 39 AL567376 LY6/PLAUR domain containing 1 LYPD1 116372 NM_001077427 /// NM_144586 /// XM_005263583 /// XM_005263584 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 212910_at W19873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W19873 /FEA=EST /DB_XREF=gi:1295962 /DB_XREF=est:zb40g01.r1 /CLONE=IMAGE:306096 /UG=Hs.82508 HRIHFB2206 protein W19873 THAP domain containing 11 THAP11 57215 NM_020457 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212911_at AB023179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023179.1 /DEF=Homo sapiens mRNA for KIAA0962 protein, partial cds. /FEA=mRNA /GEN=KIAA0962 /PROD=KIAA0962 protein /DB_XREF=gi:4589567 /UG=Hs.9059 KIAA0962 protein AB023179 DnaJ (Hsp40) homolog, subfamily C, member 16 DNAJC16 23341 NM_001287811 /// NM_015291 /// NR_109898 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 212912_at AI992251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI992251 /FEA=EST /DB_XREF=gi:5839156 /DB_XREF=est:ws41d12.x1 /CLONE=IMAGE:2499767 /UG=Hs.184581 ESTs AI992251 ribosomal protein S6 kinase, 90kDa, polypeptide 2 RPS6KA2 6196 NM_001006932 /// NM_021135 /// XM_005267092 /// XM_006715549 0001556 // oocyte maturation // inferred from electronic annotation /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060047 // heart contraction // inferred from electronic annotation /// 0070613 // regulation of protein processing // inferred from electronic annotation /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212913_at BE674960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674960 /FEA=EST /DB_XREF=gi:10035501 /DB_XREF=est:7f11a09.x1 /CLONE=IMAGE:3294328 /UG=Hs.112193 mutS (E. coli) homolog 5 BE674960 MSH5-SAPCD1 readthrough (NMD candidate) /// suppressor APC domain containing 1 MSH5-SAPCD1 /// SAPCD1 401251 /// 100532732 NM_001039651 /// NR_037846 0000710 // meiotic mismatch repair // /// 0006200 // ATP catabolic process // /// 0006298 // mismatch repair // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007131 // reciprocal meiotic recombination // /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007136 // meiotic prophase II // traceable author statement /// 0045143 // homologous chromosome segregation // /// 0051026 // chiasma assembly // 0000795 // synaptonemal complex // /// 0032300 // mismatch repair complex // 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // 212914_at AV648364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV648364 /FEA=EST /DB_XREF=gi:9869378 /DB_XREF=est:AV648364 /CLONE=GLCBIF04 /UG=Hs.152151 plakophilin 4 AV648364 chromobox homolog 7 CBX7 23492 NM_175709 /// XM_005261413 /// XM_006724174 /// XM_006724175 /// XM_006724176 /// XM_006724177 /// XM_006724178 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from electronic annotation 212915_at AL569804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL569804 /FEA=EST /DB_XREF=gi:12925507 /DB_XREF=est:AL569804 /CLONE=CS0DI002YJ15 (3 prime) /UG=Hs.177635 KIAA1095 protein AL569804 PDZ domain containing ring finger 3 PDZRN3 23024 NM_015009 /// XM_005264718 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity 0031594 // neuromuscular junction // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212916_at AW249934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW249934 /FEA=EST /DB_XREF=gi:6592927 /DB_XREF=est:2821853.3prime /CLONE=IMAGE:2821853 /UG=Hs.285641 KIAA1111 protein AW249934 PHD finger protein 8 PHF8 23133 NM_001184896 /// NM_001184897 /// NM_001184898 /// NM_015107 /// XM_005261996 /// XM_005261997 /// XM_005261998 /// XM_005261999 /// XM_005262000 /// XM_006724585 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0035574 // histone H4-K20 demethylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061188 // negative regulation of chromatin silencing at rDNA // inferred from direct assay /// 0070544 // histone H3-K36 demethylation // inferred from direct assay /// 0071557 // histone H3-K27 demethylation // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from direct assay /// 0032452 // histone demethylase activity // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0035575 // histone demethylase activity (H4-K20 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from direct assay 212917_x_at AI814728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814728 /FEA=EST /DB_XREF=gi:5425943 /DB_XREF=est:wk66h11.x1 /CLONE=IMAGE:2420421 /UG=Hs.192570 hypothetical protein FLJ22028 AI814728 RecQ helicase-like RECQL 5965 NM_002907 /// NM_032941 /// XM_005253461 /// XM_005253462 /// XM_005253463 /// XM_005253464 /// XM_006719133 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation 212918_at AI962943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962943 /FEA=EST /DB_XREF=gi:5755656 /DB_XREF=est:wt25b06.x1 /CLONE=IMAGE:2508467 /UG=Hs.192570 hypothetical protein FLJ22028 AI962943 RecQ helicase-like RECQL 5965 NM_002907 /// NM_032941 /// XM_005253461 /// XM_005253462 /// XM_005253463 /// XM_005253464 /// XM_006719133 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from electronic annotation 212919_at AV715578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV715578 /FEA=EST /DB_XREF=gi:10797095 /DB_XREF=est:AV715578 /CLONE=DCBBJG09 /UG=Hs.21056 Homo sapiens cDNA: FLJ21366 fis, clone COL03012, highly similar to AB002445 Homo sapiens mRNA from chromosome 5q21-22 AV715578 decapping mRNA 2 DCP2 167227 NM_001242377 /// NM_152624 /// NR_038352 /// XM_005271914 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016896 // exoribonuclease activity, producing 5'-phosphomonoesters // traceable author statement /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from direct assay 212920_at AV682285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV682285 /FEA=EST /DB_XREF=gi:10284148 /DB_XREF=est:AV682285 /CLONE=GKBACA04 /UG=Hs.227630 RE1-silencing transcription factor AV682285 RE1-silencing transcription factor REST 5978 NM_001193508 /// NM_005612 /// XM_005265760 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045665 // negative regulation of neuron differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0060379 // cardiac muscle cell myoblast differentiation // inferred from sequence or structural similarity /// 0070933 // histone H4 deacetylation // inferred from direct assay /// 0071257 // cellular response to electrical stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from mutant phenotype /// 2000706 // negative regulation of dense core granule biogenesis // inferred from sequence or structural similarity /// 2000740 // negative regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype /// 2000798 // negative regulation of amniotic stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212921_at AF070592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070592.1 /DEF=Homo sapiens clone 24503 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387967 /UG=Hs.66170 HSKM-B protein AF070592 SET and MYND domain containing 2 SMYD2 56950 NM_020197 /// XR_426790 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010452 // histone H3-K36 methylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0018026 // peptidyl-lysine monomethylation // inferred from direct assay /// 0018027 // peptidyl-lysine dimethylation // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0043516 // regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity 0000993 // RNA polymerase II core binding // inferred from sequence or structural similarity /// 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046975 // histone methyltransferase activity (H3-K36 specific) // inferred from sequence or structural similarity 212922_s_at AI809870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI809870 /FEA=EST /DB_XREF=gi:5396436 /DB_XREF=est:wf59c03.x1 /CLONE=IMAGE:2359876 /UG=Hs.66170 HSKM-B protein AI809870 SET and MYND domain containing 2 SMYD2 56950 NM_020197 /// XR_426790 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010452 // histone H3-K36 methylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0018026 // peptidyl-lysine monomethylation // inferred from direct assay /// 0018027 // peptidyl-lysine dimethylation // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0043516 // regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity 0000993 // RNA polymerase II core binding // inferred from sequence or structural similarity /// 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046975 // histone methyltransferase activity (H3-K36 specific) // inferred from sequence or structural similarity 212923_s_at AK024828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024828.1 /DEF=Homo sapiens cDNA: FLJ21175 fis, clone CAS11071. /FEA=mRNA /DB_XREF=gi:10437233 /UG=Hs.69388 hypothetical protein FLJ20505 AK024828 PX domain containing 1 PXDC1 221749 NM_183373 /// XR_241883 0007154 // cell communication // inferred from electronic annotation 0035091 // phosphatidylinositol binding // inferred from electronic annotation 212924_s_at N37057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N37057 /FEA=EST /DB_XREF=gi:1158199 /DB_XREF=est:yy41a06.s1 /CLONE=IMAGE:273778 /UG=Hs.76719 U6 snRNA-associated Sm-like protein N37057 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM4 25804 NM_001252129 /// NM_012321 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005688 // U6 snRNP // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212925_at AA143765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA143765 /FEA=EST /DB_XREF=gi:1713188 /DB_XREF=est:zo31e02.s1 /CLONE=IMAGE:588506 /UG=Hs.71779 Homo sapiens DNA from chromosome 19, cosmid F21856 AA143765 mitotic spindle positioning MISP 126353 NM_173481 /// XM_005259493 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 212926_at AW183677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW183677 /FEA=EST /DB_XREF=gi:6452191 /DB_XREF=est:xj86e07.x1 /CLONE=IMAGE:2664132 /UG=Hs.103283 KIAA0594 protein AW183677 structural maintenance of chromosomes 5 SMC5 23137 NM_015110 /// XM_005251837 /// XM_005251838 /// XM_005251839 0000722 // telomere maintenance via recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034184 // positive regulation of maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030915 // Smc5-Smc6 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 212927_at AB011166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011166.1 /DEF=Homo sapiens mRNA for KIAA0594 protein, partial cds. /FEA=mRNA /GEN=KIAA0594 /PROD=KIAA0594 protein /DB_XREF=gi:3043711 /UG=Hs.103283 KIAA0594 protein AB011166 structural maintenance of chromosomes 5 SMC5 23137 NM_015110 /// XM_005251837 /// XM_005251838 /// XM_005251839 0000722 // telomere maintenance via recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034184 // positive regulation of maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030915 // Smc5-Smc6 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 212928_at AL050331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050331 /DEF=Human DNA sequence from clone 486I3 on chromosome 6q22.1-22.3. Contains the part of a gene for a novel protein, the gene for KIAA0721 (NAP (Nucleosome Assembly Protein) domain containg protein), the TSPYL gene for TSPY-like (testis specific protei... /FEA=mRNA_1 /DB_XREF=gi:5668655 /UG=Hs.284141 KIAA0721 protein /FL=gb:NM_021648.1 AL050331 TSPY-like 4 TSPYL4 23270 NM_021648 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 212929_s_at W68158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W68158 /FEA=EST /DB_XREF=gi:1377028 /DB_XREF=est:zd42b02.s1 /CLONE=IMAGE:343275 /UG=Hs.13273 KIAA0592 protein W68158 family with sequence similarity 21, member A /// family with sequence similarity 21, member C /// uncharacterized LOC101930591 FAM21A /// FAM21C /// LOC101930591 253725 /// 387680 /// 101930591 NM_001005751 /// NM_001169106 /// NM_001169107 /// NM_001291398 /// NM_015262 /// NM_018232 /// XM_005269805 /// XM_005269806 /// XM_005269807 /// XM_005269808 /// XM_005269810 /// XM_006717831 /// XM_006717832 /// XR_247516 0006810 // transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay /// 0071203 // WASH complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 212930_at AW576457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW576457 /FEA=EST /DB_XREF=gi:7247996 /DB_XREF=est:UI-HF-BR0p-aji-a-01-0-UI.s1 /CLONE=IMAGE:3074568 /UG=Hs.20952 Homo sapiens clone 24411 mRNA sequence AW576457 ATPase, Ca++ transporting, plasma membrane 1 ATP2B1 490 NM_001001323 /// NM_001682 /// XM_005268919 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212931_at AB006630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006630.1 /DEF=Homo sapiens mRNA for KIAA0292 gene, partial cds. /FEA=mRNA /GEN=KIAA0292 /DB_XREF=gi:2564331 /UG=Hs.201668 transcription factor 20 (AR1) AB006630 transcription factor 20 (AR1) TCF20 6942 NM_005650 /// NM_181492 /// XM_005261722 /// XM_005261723 /// XM_005261724 /// XM_005276955 /// XM_005276956 /// XM_005276957 /// XM_006724313 /// XM_006724314 /// XM_006725781 /// XM_006725782 /// XM_006725783 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 212932_at AK022494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022494.1 /DEF=Homo sapiens cDNA FLJ12432 fis, clone NT2RM1000018, highly similar to Human mRNA for KIAA0066 gene. /FEA=mRNA /DB_XREF=gi:10433912 /UG=Hs.227881 RAB3 GTPase-ACTIVATING PROTEIN AK022494 RAB3 GTPase activating protein subunit 1 (catalytic) RAB3GAP1 22930 NM_001172435 /// NM_012233 /// XR_427077 /// XR_427078 0007420 // brain development // inferred from mutant phenotype /// 0021854 // hypothalamus development // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 212933_x_at AA961748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA961748 /FEA=EST /DB_XREF=gi:3133912 /DB_XREF=est:or60d03.s1 /CLONE=IMAGE:1600229 /UG=Hs.180842 ribosomal protein L13 AA961748 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212934_at AI245523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI245523 /FEA=EST /DB_XREF=gi:3840920 /DB_XREF=est:qk25c04.x1 /CLONE=IMAGE:1869990 /UG=Hs.155572 Human clone 23801 mRNA sequence AI245523 UBX domain protein 2B UBXN2B 137886 NM_001077619 /// XM_005251165 /// XM_005251166 /// XR_242453 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 212935_at AB002360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002360.1 /DEF=Human mRNA for KIAA0362 gene, partial cds. /FEA=mRNA /GEN=KIAA0362 /DB_XREF=gi:2224664 /UG=Hs.25515 MCF.2 cell line derived transforming sequence-like AB002360 MCF.2 cell line derived transforming sequence-like MCF2L 23263 NM_001112732 /// NM_024979 /// XM_005268307 /// XM_005268308 /// XM_005268309 /// XM_005268310 /// XM_005268312 /// XM_005268313 /// XM_005268314 /// XM_005268315 /// XM_005268316 /// XM_006719966 /// XM_006719967 /// XM_006719968 /// XR_429282 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from electronic annotation 212936_at AI927701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927701 /FEA=EST /DB_XREF=gi:5663665 /DB_XREF=est:wo85h11.x1 /CLONE=IMAGE:2462181 /UG=Hs.25307 Homo sapiens clone 24812 mRNA sequence AI927701 family with sequence similarity 172, member A FAM172A 83989 NM_001163417 /// NM_001163418 /// NM_032042 /// NR_028080 /// XM_005272103 /// XM_005272104 /// XM_005272105 /// XM_005272106 /// XM_005272107 /// XM_005272108 /// XM_005272109 /// XM_005272110 /// XM_005272111 /// XM_006714717 /// XM_006714718 /// XM_006714719 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 212937_s_at M20776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M20776.1 /DEF=Homo sapiens, alpha-1 (VI) collagen. /FEA=mRNA /DB_XREF=gi:180909 /UG=Hs.25459 Homo sapiens, alpha-1 (VI) collagen M20776 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 212938_at M20776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M20776.1 /DEF=Homo sapiens, alpha-1 (VI) collagen. /FEA=mRNA /DB_XREF=gi:180909 /UG=Hs.25459 Homo sapiens, alpha-1 (VI) collagen M20776 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 212939_at M20776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M20776.1 /DEF=Homo sapiens, alpha-1 (VI) collagen. /FEA=mRNA /DB_XREF=gi:180909 /UG=Hs.25459 Homo sapiens, alpha-1 (VI) collagen M20776 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 212940_at BE350145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE350145 /FEA=EST /DB_XREF=gi:9261998 /DB_XREF=est:ht10a07.x1 /CLONE=IMAGE:3146292 /UG=Hs.25459 Homo sapiens, alpha-1 (VI) collagen BE350145 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 212942_s_at AB033025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033025.1 /DEF=Homo sapiens mRNA for KIAA1199 protein, partial cds. /FEA=mRNA /GEN=KIAA1199 /PROD=KIAA1199 protein /DB_XREF=gi:6330400 /UG=Hs.50081 KIAA1199 protein AB033025 cell migration inducing protein, hyaluronan binding CEMIP 57214 NM_001293298 /// NM_001293304 /// NM_018689 /// XM_005254567 /// XM_005254568 /// XM_006720620 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0030214 // hyaluronan catabolic process // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay /// 1900020 // positive regulation of protein kinase C activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0046923 // ER retention sequence binding // inferred from direct assay 212943_at AB011100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011100.2 /DEF=Homo sapiens mRNA for KIAA0528 protein, partial cds. /FEA=mRNA /GEN=KIAA0528 /PROD=KIAA0528 protein /DB_XREF=gi:6683714 /UG=Hs.30656 KIAA0528 gene product AB011100 C2 calcium-dependent domain containing 5 C2CD5 9847 NM_001286173 /// NM_001286174 /// NM_001286175 /// NM_001286176 /// NM_001286177 /// NM_014802 /// XM_005253538 /// XM_005253539 /// XM_006719164 /// XM_006719165 /// XM_006719166 /// XM_006719167 /// XM_006719168 /// XM_006719169 /// XM_006719170 0006810 // transport // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0010828 // positive regulation of glucose transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0065002 // intracellular protein transmembrane transport // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from mutant phenotype /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 212944_at AK024896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024896.1 /DEF=Homo sapiens cDNA: FLJ21243 fis, clone COL01164. /FEA=mRNA /DB_XREF=gi:10437310 /UG=Hs.268016 Homo sapiens cDNA: FLJ21243 fis, clone COL01164 AK024896 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 SLC5A3 6526 NM_006933 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0015798 // myo-inositol transport // traceable author statement /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015935 // small ribosomal subunit // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005367 // myo-inositol:sodium symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 212945_s_at BE502432 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE502432 /FEA=EST /DB_XREF=gi:9704840 /DB_XREF=est:hy16a07.x1 /CLONE=IMAGE:3197460 /UG=Hs.23763 Max-interacting protein BE502432 MGA, MAX dimerization protein MGA 23269 NM_001080541 /// NM_001164273 /// XM_005254243 /// XM_005254244 /// XM_005254245 /// XM_005254246 /// XM_005254247 /// XM_005254248 /// XM_005254249 /// XM_005254252 /// XM_005254253 /// XM_005254254 /// XM_006720442 /// XM_006720443 /// XM_006720444 /// XM_006720445 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 212946_at AK025432 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025432.1 /DEF=Homo sapiens cDNA: FLJ21779 fis, clone HEP00210. /FEA=mRNA /DB_XREF=gi:10437943 /UG=Hs.151385 KIAA0564 protein AK025432 von Willebrand factor A domain containing 8 VWA8 23078 NM_001009814 /// NM_015058 /// XM_006719790 /// XM_006719791 /// XM_006719792 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 212947_at AL031685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031685 /DEF=Human DNA sequence from clone RP5-963K23 on chromosome 20q13.11-13.2 Contains a KRT18 (Keratin type I, Cytoskeletal 18 (Cytokeratin 18, CK18,CYK18)) pseudogene, a gene for a novel protein, the gene for spermatogenesis associated protein PD1 (KIAA0... /FEA=mRNA_3 /DB_XREF=gi:9368423 /UG=Hs.12785 KIAA0939 protein AL031685 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 SLC9A8 23315 NM_001260491 /// NM_015266 /// NR_048537 /// NR_048538 /// NR_048539 /// NR_048540 /// XM_006723756 /// XM_006723757 /// XM_006723758 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation /// 0015386 // potassium:proton antiporter activity // inferred from electronic annotation 212948_at AB020716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020716.1 /DEF=Homo sapiens mRNA for KIAA0909 protein, partial cds. /FEA=mRNA /GEN=KIAA0909 /PROD=KIAA0909 protein /DB_XREF=gi:4240306 /UG=Hs.107362 KIAA0909 protein AB020716 calmodulin binding transcription activator 2 CAMTA2 23125 NM_001171166 /// NM_001171167 /// NM_001171168 /// NM_015099 /// XM_006721478 /// XM_006721479 /// XM_006721480 /// XM_006721481 /// XM_006721482 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from genetic interaction /// 0042826 // histone deacetylase binding // inferred from direct assay 212949_at D38553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38553.1 /DEF=Homo sapiens HCAP-H mRNA, partial cds. /FEA=mRNA /GEN=HCAP-H /DB_XREF=gi:559714 /UG=Hs.1192 KIAA0074 protein D38553 non-SMC condensin I complex, subunit H NCAPH 23397 NM_001281710 /// NM_001281711 /// NM_001281712 /// NM_015341 /// XM_005263907 /// XM_005263908 /// XM_006712388 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 212950_at BF941499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF941499 /FEA=EST /DB_XREF=gi:12358819 /DB_XREF=est:nac74e09.x1 /CLONE=IMAGE:3439985 /UG=Hs.22039 KIAA0758 protein BF941499 G protein-coupled receptor 116 GPR116 221395 NM_001098518 /// NM_015234 /// XM_005248892 /// XM_005248893 /// XM_005248894 /// XM_005248895 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212951_at N95226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N95226 /FEA=EST /DB_XREF=gi:1267507 /DB_XREF=est:zb53f09.s1 /CLONE=IMAGE:307337 /UG=Hs.22039 KIAA0758 protein N95226 G protein-coupled receptor 116 GPR116 221395 NM_001098518 /// NM_015234 /// XM_005248892 /// XM_005248893 /// XM_005248894 /// XM_005248895 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212952_at AA910371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA910371 /FEA=EST /DB_XREF=gi:3049661 /DB_XREF=est:ok83h10.s1 /CLONE=IMAGE:1520611 /UG=Hs.16488 calreticulin AA910371 CTC-425F1.4 212953_x_at BE251303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE251303 /FEA=EST /DB_XREF=gi:9121413 /DB_XREF=est:601107814F1 /CLONE=IMAGE:3344018 /UG=Hs.16488 calreticulin BE251303 calreticulin CALR 811 NM_004343 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002502 // peptide antigen assembly with MHC class I protein complex // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from genetic interaction /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from genetic interaction /// 0045787 // positive regulation of cell cycle // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050821 // protein stabilization // traceable author statement /// 0051208 // sequestering of calcium ion // traceable author statement /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from genetic interaction /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005844 // polysome // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042824 // MHC class I peptide loading complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement /// 0071682 // endocytic vesicle lumen // traceable author statement 0001849 // complement component C1q binding // traceable author statement /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0030246 // carbohydrate binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement 212954_at AF263541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF263541.1 /DEF=Homo sapiens protein kinase DYRK4 (DYRK4) mRNA, partial cds. /FEA=mRNA /GEN=DYRK4 /PROD=protein kinase DYRK4 /DB_XREF=gi:9652079 /UG=Hs.17154 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 AF263541 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 DYRK4 8798 NM_001282285 /// NM_001282286 /// NM_003845 /// NR_104115 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212955_s_at AL037557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037557 /FEA=EST /DB_XREF=gi:5928180 /DB_XREF=est:DKFZp564H2472_r1 /CLONE=DKFZp564H2472 /UG=Hs.181357 laminin receptor 1 (67kD, ribosomal protein SA) AL037557 polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa POLR2I 5438 NM_006233 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001193 // maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // not recorded /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212956_at AI348094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348094 /FEA=EST /DB_XREF=gi:4085300 /DB_XREF=est:qp61g12.x1 /CLONE=IMAGE:1927558 /UG=Hs.90419 KIAA0882 protein AI348094 TBC1 domain family, member 9 (with GRAM domain) TBC1D9 23158 NM_015130 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 212957_s_at AU154785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154785 /FEA=EST /DB_XREF=gi:11016306 /DB_XREF=est:AU154785 /CLONE=NT2RP4002888 /UG=Hs.31532 Homo sapiens mRNA; cDNA DKFZp434F172 (from clone DKFZp434F172) AU154785 long intergenic non-protein coding RNA 1278 LINC01278 92249 NR_015353 212958_x_at AI022882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI022882 /FEA=EST /DB_XREF=gi:3238123 /DB_XREF=est:ow54e04.s1 /CLONE=IMAGE:1650654 /UG=Hs.83920 peptidylglycine alpha-amidating monooxygenase AI022882 peptidylglycine alpha-amidating monooxygenase PAM 5066 NM_000919 /// NM_001177306 /// NM_138766 /// NM_138821 /// NM_138822 /// NR_033440 /// XM_006714632 /// XM_006714633 /// XM_006714634 /// XM_006714635 /// XM_006714636 /// XM_006714637 /// XM_006714638 /// XM_006714639 /// XM_006714640 0001519 // peptide amidation // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006518 // peptide metabolic process // inferred from electronic annotation /// 0006518 // peptide metabolic process // non-traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from mutant phenotype /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0018032 // protein amidation // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // non-traceable author statement /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004504 // peptidylglycine monooxygenase activity // inferred from direct assay /// 0004598 // peptidylamidoglycolate lyase activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212959_s_at AK001821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001821.1 /DEF=Homo sapiens cDNA FLJ10959 fis, clone PLACE1000562. /FEA=mRNA /DB_XREF=gi:7023328 /UG=Hs.7041 hypothetical protein DKFZp762B226 AK001821 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits GNPTAB 79158 NM_024312 /// XM_006719593 0007040 // lysosome organization // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003976 // UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212960_at BE646554 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646554 /FEA=EST /DB_XREF=gi:9970865 /DB_XREF=est:7e89a04.x1 /CLONE=IMAGE:3292302 /UG=Hs.90419 KIAA0882 protein BE646554 TBC1 domain family, member 9 (with GRAM domain) TBC1D9 23158 NM_015130 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 212961_x_at L43578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L43578.1 /DEF=Homo sapiens (clone 115392) mRNA. /FEA=mRNA /DB_XREF=gi:899067 /UG=Hs.82171 Homo sapiens (clone 115392) mRNA L43578 chromosome X open reading frame 40B CXorf40B 541578 NM_001013845 /// XM_005274698 /// XM_005274699 /// XM_005274700 /// XM_005274701 /// XM_005274702 /// XM_006724825 /// XM_006724826 /// XM_006724827 0005515 // protein binding // inferred from physical interaction 212962_at AK023573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023573.1 /DEF=Homo sapiens cDNA FLJ13511 fis, clone PLACE1005331, highly similar to Homo sapiens 7h3 protein mRNA. /FEA=mRNA /DB_XREF=gi:10435545 /UG=Hs.9291 Homo sapiens cDNA FLJ13511 fis, clone PLACE1005331, highly similar to Homo sapiens 7h3 protein mRNA AK023573 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) SYDE1 85360 NM_033025 /// XM_005260126 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032862 // activation of Rho GTPase activity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 212963_at BF968960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF968960 /FEA=EST /DB_XREF=gi:12336175 /DB_XREF=est:602270156F1 /CLONE=IMAGE:4358628 /UG=Hs.180532 glucose phosphate isomerase BF968960 TM2 domain containing 1 TM2D1 83941 NM_032027 /// XM_005271250 /// XR_246299 0006915 // apoptotic process // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 212964_at AI912206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI912206 /FEA=EST /DB_XREF=gi:5632061 /DB_XREF=est:wd71e08.x1 /CLONE=IMAGE:2337062 /UG=Hs.109445 KIAA1020 protein AI912206 hypermethylated in cancer 2 HIC2 23119 NM_015094 /// XM_005261395 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212965_at BE465318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE465318 /FEA=EST /DB_XREF=gi:9511093 /DB_XREF=est:hw14f11.x1 /CLONE=IMAGE:3182925 /UG=Hs.109445 KIAA1020 protein BE465318 hypermethylated in cancer 2 HIC2 23119 NM_015094 /// XM_005261395 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212966_at AL043112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043112 /FEA=EST /DB_XREF=gi:5935736 /DB_XREF=est:DKFZp434D1023_s1 /CLONE=DKFZp434D1023 /UG=Hs.109445 KIAA1020 protein AL043112 hypermethylated in cancer 2 HIC2 23119 NM_015094 /// XM_005261395 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212967_x_at AW148801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW148801 /FEA=EST /DB_XREF=gi:6196697 /DB_XREF=est:xf04e10.x1 /CLONE=IMAGE:2617098 /UG=Hs.179662 nucleosome assembly protein 1-like 1 AW148801 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 212968_at BF940276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF940276 /FEA=EST /DB_XREF=gi:12357596 /DB_XREF=est:7o43e03.x1 /CLONE=IMAGE:3577036 /UG=Hs.12862 radical fringe (Drosophila) homolog BF940276 RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase RFNG 5986 NM_002917 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 212969_x_at BE222618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222618 /FEA=EST /DB_XREF=gi:8909936 /DB_XREF=est:hu49a11.x1 /CLONE=IMAGE:3173372 /UG=Hs.173043 metastasis-associated 1-like 1 BE222618 echinoderm microtubule associated protein like 3 EML3 256364 NM_153265 /// XM_005273876 /// XM_005273877 /// XM_005273878 /// XM_006718489 /// XM_006718490 /// XM_006718491 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 212970_at AI694303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694303 /FEA=EST /DB_XREF=gi:4971643 /DB_XREF=est:wd45c03.x1 /CLONE=IMAGE:2331076 /UG=Hs.15740 Homo sapiens mRNA; cDNA DKFZp434E033 (from clone DKFZp434E033) AI694303 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 212971_at AI769685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769685 /FEA=EST /DB_XREF=gi:5236194 /DB_XREF=est:wj25f08.x1 /CLONE=IMAGE:2403879 /UG=Hs.159604 cysteinyl-tRNA synthetase AI769685 cysteinyl-tRNA synthetase CARS 833 NM_001014437 /// NM_001014438 /// NM_001194997 /// NM_001751 /// NM_139273 /// NR_036542 /// XM_006718340 /// XM_006718341 /// XM_006725129 /// XM_006725130 /// XR_428857 /// XR_430701 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006423 // cysteinyl-tRNA aminoacylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000049 // tRNA binding // inferred from mutant phenotype /// 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004817 // cysteine-tRNA ligase activity // inferred from direct assay /// 0004817 // cysteine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 212972_x_at AL080130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080130.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E033 (from clone DKFZp434E033). /FEA=mRNA /DB_XREF=gi:5262569 /UG=Hs.15740 Homo sapiens mRNA; cDNA DKFZp434E033 (from clone DKFZp434E033) AL080130 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 212973_at AI692341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI692341 /FEA=EST /DB_XREF=gi:4969681 /DB_XREF=est:wd85g04.x1 /CLONE=IMAGE:2338422 /UG=Hs.79886 ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase) AI692341 ribose 5-phosphate isomerase A RPIA 22934 NM_144563 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from electronic annotation /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004751 // ribose-5-phosphate isomerase activity // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 212974_at AI808958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI808958 /FEA=EST /DB_XREF=gi:5395524 /DB_XREF=est:wf67a09.x1 /CLONE=IMAGE:2360632 /UG=Hs.18166 KIAA0870 protein AI808958 DENN/MADD domain containing 3 DENND3 22898 NM_014957 /// XM_005250838 /// XM_005250839 /// XM_005250840 /// XM_005250841 /// XM_005250842 /// XM_005250843 /// XM_005250844 /// XM_005250845 /// XR_242384 0008333 // endosome to lysosome transport // inferred from sequence or structural similarity /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 212975_at AB020677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020677.2 /DEF=Homo sapiens mRNA for KIAA0870 protein, partial cds. /FEA=mRNA /GEN=KIAA0870 /PROD=KIAA0870 protein /DB_XREF=gi:6635136 /UG=Hs.18166 KIAA0870 protein AB020677 DENN/MADD domain containing 3 DENND3 22898 NM_014957 /// XM_005250838 /// XM_005250839 /// XM_005250840 /// XM_005250841 /// XM_005250842 /// XM_005250843 /// XM_005250844 /// XM_005250845 /// XR_242384 0008333 // endosome to lysosome transport // inferred from sequence or structural similarity /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 212976_at R41498 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R41498 /FEA=EST /DB_XREF=gi:816800 /DB_XREF=est:yf86h08.s1 /CLONE=IMAGE:29486 /UG=Hs.199243 KIAA0231 protein R41498 leucine rich repeat containing 8 family, member B LRRC8B 23507 NM_001134476 /// NM_015350 /// XM_005270701 /// XM_005270702 /// XM_005270703 /// XM_005270704 /// XM_006710541 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212977_at AI817041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817041 /FEA=EST /DB_XREF=gi:5436120 /DB_XREF=est:wj76c06.x1 /CLONE=IMAGE:2408746 /UG=Hs.23016 G protein-coupled receptor AI817041 atypical chemokine receptor 3 ACKR3 57007 NM_001047841 /// NM_020311 /// XM_005246097 /// XM_005246098 /// XM_006712640 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0070098 // chemokine-mediated signaling pathway // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from mutant phenotype /// 0019958 // C-X-C chemokine binding // inferred from mutant phenotype 212978_at AU146004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146004 /FEA=EST /DB_XREF=gi:11007525 /DB_XREF=est:AU146004 /CLONE=HEMBA1006523 /UG=Hs.199243 KIAA0231 protein AU146004 leucine rich repeat containing 8 family, member B LRRC8B 23507 NM_001134476 /// NM_015350 /// XM_005270701 /// XM_005270702 /// XM_005270703 /// XM_005270704 /// XM_006710541 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 212979_s_at AW293343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW293343 /FEA=EST /DB_XREF=gi:6699905 /DB_XREF=est:UI-H-BI2-ahj-d-05-0-UI.s1 /CLONE=IMAGE:2726841 /UG=Hs.283978 Homo sapiens PRO2751 mRNA, complete cds AW293343 family with sequence similarity 115, member A /// protein FAM115A-like FAM115A /// LOC100294033 9747 /// 100294033 NM_001206938 /// NM_001206941 /// NM_014719 /// XM_003120061 /// XM_005250074 /// XM_005250075 /// XM_005250076 /// XM_005250077 /// XM_006716190 /// XM_006716191 /// XM_006716192 /// XM_006716193 212980_at AL050376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050376.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J101 (from clone DKFZp586J101). /FEA=mRNA /DB_XREF=gi:4914609 /UG=Hs.322645 Homo sapiens mRNA; cDNA DKFZp586J101 (from clone DKFZp586J101) AL050376 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) AHSA2 130872 NM_152392 /// XM_006711943 /// XM_006711944 /// XM_006711945 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0001671 // ATPase activator activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 212981_s_at BF030508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF030508 /FEA=EST /DB_XREF=gi:10738220 /DB_XREF=est:601559826F1 /CLONE=IMAGE:3829566 /UG=Hs.283978 Homo sapiens PRO2751 mRNA, complete cds BF030508 family with sequence similarity 115, member A /// protein FAM115A-like FAM115A /// LOC100294033 9747 /// 100294033 NM_001206938 /// NM_001206941 /// NM_014719 /// XM_003120061 /// XM_005250074 /// XM_005250075 /// XM_005250076 /// XM_005250077 /// XM_006716190 /// XM_006716191 /// XM_006716192 /// XM_006716193 212982_at AI621223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI621223 /FEA=EST /DB_XREF=gi:4630349 /DB_XREF=est:ts77a09.x1 /CLONE=IMAGE:2237272 /UG=Hs.4014 KIAA0946 protein; Huntingtin interacting protein H AI621223 zinc finger, DHHC-type containing 17 ZDHHC17 23390 NM_015336 /// XM_005268749 /// XM_005268750 /// XM_005268751 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from direct assay /// 0018345 // protein palmitoylation // inferred from direct assay /// 0042953 // lipoprotein transport // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015095 // magnesium ion transmembrane transporter activity // inferred from direct assay /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 212983_at NM_005343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005343.1 /DEF=Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), mRNA. /FEA=CDS /GEN=HRAS /PROD=v-Ha-ras Harvey rat sarcoma viral oncogenehomolog /DB_XREF=gi:4885424 /UG=Hs.37003 v-Ha-ras Harvey rat sarcoma viral oncogene homolog /FL=gb:NM_005343.1 NM_005343 Harvey rat sarcoma viral oncogene homolog HRAS 3265 NM_001130442 /// NM_005343 /// NM_176795 /// XM_006718217 /// XM_006725136 /// XR_242795 /// XR_430702 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred from direct assay /// 0090398 // cellular senescence // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 1900029 // positive regulation of ruffle assembly // inferred from direct assay /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay /// 2000630 // positive regulation of miRNA metabolic process // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation 212984_at BE786164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE786164 /FEA=EST /DB_XREF=gi:10207362 /DB_XREF=est:601474273F1 /CLONE=IMAGE:3877146 /UG=Hs.80285 Homo sapiens mRNA; cDNA DKFZp586C1723 (from clone DKFZp586C1723) BE786164 activating transcription factor 2 ATF2 1386 NM_001256090 /// NM_001256091 /// NM_001256092 /// NM_001256093 /// NM_001256094 /// NM_001880 /// NR_045768 /// NR_045769 /// NR_045770 /// NR_045771 /// NR_045772 /// NR_045773 /// NR_045774 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006970 // response to osmotic stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // inferred from mutant phenotype /// 0032915 // positive regulation of transforming growth factor beta2 production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred by curator /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 212985_at BF115739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF115739 /FEA=EST /DB_XREF=gi:10985215 /DB_XREF=est:7n64b08.x1 /CLONE=IMAGE:3569246 /UG=Hs.15740 Homo sapiens mRNA; cDNA DKFZp434E033 (from clone DKFZp434E033) BF115739 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 212986_s_at BF112255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF112255 /FEA=EST /DB_XREF=gi:10941945 /DB_XREF=est:7l42g09.x1 /CLONE=IMAGE:3524176 /UG=Hs.57553 tousled-like kinase 2 BF112255 tousled-like kinase 2 TLK2 11011 NM_001112707 /// NM_001284333 /// NM_001284363 /// NM_006852 /// XM_005256969 /// XM_005256970 /// XM_005256971 /// XM_005256973 /// XM_005256974 /// XM_005256975 /// XM_006721647 /// XM_006721648 /// XM_006721649 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212987_at AL031178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031178 /DEF=Human DNA sequence from clone 341E18 on chromosome 6p11.2-12.3. Contains a SerineThreonine Protein Kinase gene (presumptive isolog of a Rat gene) and a novel alternatively spliced gene. Contains a putative CpG island, ESTs and GSSs /FEA=mRNA_2 /DB_XREF=gi:3550040 /UG=Hs.11050 F-box only protein 9 AL031178 F-box protein 9 FBXO9 26268 NM_012347 /// NM_033480 /// NM_033481 /// XM_005248995 /// XM_005248996 /// XM_006715050 /// XM_006715051 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212988_x_at AL515810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515810 /FEA=EST /DB_XREF=gi:12779303 /DB_XREF=est:AL515810 /CLONE=CS0DA001YI24 (3 prime) /UG=Hs.14376 actin, gamma 1 AL515810 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 212989_at AI377497 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI377497 /FEA=EST /DB_XREF=gi:4187350 /DB_XREF=est:tc37c06.x1 /CLONE=IMAGE:2066794 /UG=Hs.153716 Homo sapiens mRNA for Hmob33 protein, 3 untranslated region AI377497 sphingomyelin synthase 1 SGMS1 259230 NM_147156 /// XM_005269675 /// XM_006717748 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033188 // sphingomyelin synthase activity // inferred from mutant phenotype /// 0047493 // ceramide cholinephosphotransferase activity // inferred from direct assay 212990_at AB020717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020717.1 /DEF=Homo sapiens mRNA for KIAA0910 protein, partial cds. /FEA=mRNA /GEN=KIAA0910 /PROD=KIAA0910 protein /DB_XREF=gi:4240308 /UG=Hs.127416 synaptojanin 1 AB020717 synaptojanin 1 SYNJ1 8867 NM_001160302 /// NM_001160306 /// NM_003895 /// NM_203446 /// XM_005261076 /// XM_005261080 /// XM_005261081 /// XM_006724058 /// XM_006724059 /// XM_006724060 /// XM_006724061 /// XM_006724062 /// XM_006724063 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0016191 // synaptic vesicle uncoating // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0048489 // synaptic vesicle transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030117 // membrane coat // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 212991_at AL137520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137520.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C0118 (from clone DKFZp434C0118); partial cds. /FEA=mRNA /GEN=DKFZp434C0118 /PROD=hypothetical protein /DB_XREF=gi:6808183 /UG=Hs.11050 F-box only protein 9 AL137520 F-box protein 9 FBXO9 26268 NM_012347 /// NM_033480 /// NM_033481 /// XM_005248995 /// XM_005248996 /// XM_006715050 /// XM_006715051 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 212992_at AI935123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935123 /FEA=EST /DB_XREF=gi:5673993 /DB_XREF=est:wp13h09.x1 /CLONE=IMAGE:2464769 /UG=Hs.57548 ESTs AI935123 AHNAK nucleoprotein 2 AHNAK2 113146 NM_138420 /// XM_005267299 0001778 // plasma membrane repair // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0042383 // sarcolemma // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 212993_at AA114166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA114166 /FEA=EST /DB_XREF=gi:1668052 /DB_XREF=est:zn75c03.s1 /CLONE=IMAGE:564004 /UG=Hs.23964 sin3-associated polypeptide, 18kD AA114166 NACC family member 2, BEN and BTB (POZ) domain containing NACC2 138151 NM_144653 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010608 // posttranscriptional regulation of gene expression // inferred from mutant phenotype /// 0016575 // histone deacetylation // inferred from direct assay /// 0034629 // cellular protein complex localization // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 1900477 // negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0016581 // NuRD complex // inferred from direct assay /// 0016604 // nuclear body // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction 212994_at BE543527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE543527 /FEA=EST /DB_XREF=gi:9772172 /DB_XREF=est:601070669F1 /CLONE=IMAGE:3456857 /UG=Hs.16411 hypothetical protein LOC57187 BE543527 THO complex 2 THOC2 57187 NM_001081550 /// NM_020449 /// XM_005262447 /// XM_005262450 /// XM_006724767 /// XM_006724768 /// XM_006724769 /// XM_006724770 /// XM_006724771 /// XM_006724772 /// XM_006724773 /// XR_430547 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 212995_x_at BG255188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG255188 /FEA=EST /DB_XREF=gi:12765004 /DB_XREF=est:602369727F1 /CLONE=IMAGE:4477807 /UG=Hs.3343 phosphoglycerate dehydrogenase BG255188 mitotic spindle organizing protein 2A /// mitotic spindle organizing protein 2B /// phosphoglycerate dehydrogenase MZT2A /// MZT2B /// PHGDH 26227 /// 80097 /// 653784 NM_001085365 /// NM_006623 /// NM_025029 /// XM_005263741 /// XM_005263742 /// XM_005263792 /// XM_005263795 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0006566 // threonine metabolic process // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021782 // glial cell development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // inferred from direct assay /// 0008274 // gamma-tubulin ring complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004617 // phosphoglycerate dehydrogenase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 212996_s_at AI803485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803485 /FEA=EST /DB_XREF=gi:5368879 /DB_XREF=est:tc17f11.x1 /CLONE=IMAGE:2064141 /UG=Hs.18759 KIAA0539 gene product AI803485 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) URB1 9875 NM_014825 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 212997_s_at AU151689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151689 /FEA=EST /DB_XREF=gi:11013210 /DB_XREF=est:AU151689 /CLONE=NT2RP2005862 /UG=Hs.57553 tousled-like kinase 2 AU151689 tousled-like kinase 2 TLK2 11011 NM_001112707 /// NM_001284333 /// NM_001284363 /// NM_006852 /// XM_005256969 /// XM_005256970 /// XM_005256971 /// XM_005256973 /// XM_005256974 /// XM_005256975 /// XM_006721647 /// XM_006721648 /// XM_006721649 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 212998_x_at AI583173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI583173 /FEA=EST /DB_XREF=gi:4569070 /DB_XREF=est:tq64e04.x1 /CLONE=IMAGE:2213598 /UG=Hs.73931 major histocompatibility complex, class II, DQ beta 1 AI583173 major histocompatibility complex, class II, DQ beta 1 /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// LOC101060835 3119 /// 101060835 NM_001243961 /// NM_001243962 /// NM_002123 /// XM_003960955 /// XM_005276082 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 212999_x_at AW276186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW276186 /FEA=EST /DB_XREF=gi:6663216 /DB_XREF=est:xr07c12.x1 /CLONE=IMAGE:2759446 /UG=Hs.73931 major histocompatibility complex, class II, DQ beta 1 AW276186 major histocompatibility complex, class II, DQ beta 1 /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// LOC101060835 3119 /// 101060835 NM_001243961 /// NM_001243962 /// NM_002123 /// XM_003960955 /// XM_005276082 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 213000_at AP000693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AP000693 /DEF=Homo sapiens genomic DNA, chromosome 21q22.2, PCR fragment from BAC clone:KB739C11, CBR1-HLCS region /FEA=mRNA /DB_XREF=gi:6693637 /UG=Hs.70359 KIAA0136 protein AP000693 MORC family CW-type zinc finger 3 MORC3 23515 NM_015358 /// XM_006723985 /// XM_006723986 0006468 // protein phosphorylation // inferred from direct assay /// 0007569 // cell aging // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213001_at AF007150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007150.1 /DEF=Homo sapiens clone 23767 and 23782 mRNA sequences. /FEA=mRNA /DB_XREF=gi:2852628 /UG=Hs.8025 Homo sapiens clone 23767 and 23782 mRNA sequences AF007150 angiopoietin-like 2 ANGPTL2 23452 NM_012098 /// XM_006717030 0007275 // multicellular organismal development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 213002_at AA770596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA770596 /FEA=EST /DB_XREF=gi:2821834 /DB_XREF=est:oe54a06.s1 /CLONE=IMAGE:1415410 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) AA770596 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005813 // centrosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 213003_s_at BF061054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF061054 /FEA=EST /DB_XREF=gi:10819964 /DB_XREF=est:7i79f07.x1 /CLONE=IMAGE:3340933 /UG=Hs.76722 CCAATenhancer binding protein (CEBP), delta BF061054 scaffolding protein involved in DNA repair SPIDR 23514 NM_001080394 /// NM_001282916 /// NM_001282919 /// NR_104581 /// XM_005251189 /// XM_005251191 /// XM_005251193 /// XM_005251195 /// XM_005251196 /// XM_005251197 /// XM_005251198 /// XM_005251199 /// XM_005251201 /// XM_006716443 /// XM_006716444 /// XM_006716445 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0070202 // regulation of establishment of protein localization to chromosome // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0072711 // cellular response to hydroxyurea // inferred from direct assay /// 0072757 // cellular response to camptothecin // inferred from direct assay /// 2000781 // positive regulation of double-strand break repair // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213004_at AI074333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI074333 /FEA=EST /DB_XREF=gi:3400977 /DB_XREF=est:oz84a09.x1 /CLONE=IMAGE:1682008 /UG=Hs.8025 Homo sapiens clone 23767 and 23782 mRNA sequences AI074333 angiopoietin-like 2 ANGPTL2 23452 NM_012098 /// XM_006717030 0007275 // multicellular organismal development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 213005_s_at D79994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D79994.1 /DEF=Human mRNA for KIAA0172 gene, partial cds. /FEA=mRNA /GEN=KIAA0172 /DB_XREF=gi:1136403 /UG=Hs.77546 KIAA0172 protein D79994 KN motif and ankyrin repeat domains 1 KANK1 23189 NM_001256876 /// NM_001256877 /// NM_015158 /// NM_153186 /// XM_005251410 /// XM_005251411 /// XM_005251413 /// XM_005251414 /// XM_005251415 /// XM_005251416 /// XM_005251417 /// XM_005251418 /// XM_005251419 /// XM_006716743 /// XM_006716744 /// XM_006716745 /// XM_006716746 /// XM_006716747 /// XM_006716748 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030837 // negative regulation of actin filament polymerization // inferred from direct assay /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 1900028 // negative regulation of ruffle assembly // inferred from direct assay /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay 213006_at AV655640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV655640 /FEA=EST /DB_XREF=gi:9876654 /DB_XREF=est:AV655640 /CLONE=GLCEIH09 /UG=Hs.76722 CCAATenhancer binding protein (CEBP), delta AV655640 CCAAT/enhancer binding protein (C/EBP), delta CEBPD 1052 NM_005195 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213007_at W74442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W74442 /FEA=EST /DB_XREF=gi:1384777 /DB_XREF=est:zd75e09.s1 /CLONE=IMAGE:346504 /UG=Hs.80961 polymerase (DNA directed), gamma W74442 Fanconi anemia, complementation group I FANCI 55215 NM_001113378 /// NM_018193 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0070182 // DNA polymerase binding // inferred from physical interaction 213008_at BG403615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG403615 /FEA=EST /DB_XREF=gi:13297063 /DB_XREF=est:602419331F1 /CLONE=IMAGE:4526406 /UG=Hs.80961 polymerase (DNA directed), gamma BG403615 Fanconi anemia, complementation group I FANCI 55215 NM_001113378 /// NM_018193 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0070182 // DNA polymerase binding // inferred from physical interaction 213009_s_at AK022701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022701.1 /DEF=Homo sapiens cDNA FLJ12639 fis, clone NT2RM4001938, highly similar to Homo sapiens mRNA for KIAA0898 protein. /FEA=mRNA /DB_XREF=gi:10434250 /UG=Hs.8164 Mulibrey nanism AK022701 tripartite motif containing 37 TRIM37 4591 NM_001005207 /// NM_015294 /// XM_005257385 /// XM_005257386 /// XM_005257387 /// XM_005257388 /// XM_005257389 /// XM_005257390 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0046600 // negative regulation of centriole replication // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070842 // aggresome assembly // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213010_at AI088622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI088622 /FEA=EST /DB_XREF=gi:3427681 /DB_XREF=est:qb14f06.x1 /CLONE=IMAGE:1696259 /UG=Hs.85181 v-raf-1 murine leukemia viral oncogene homolog 1 AI088622 protein kinase C, delta binding protein PRKCDBP 112464 NM_145040 0005901 // caveola // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213011_s_at BF116254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF116254 /FEA=EST /DB_XREF=gi:10985730 /DB_XREF=est:7n79g04.x1 /CLONE=IMAGE:3570991 /UG=Hs.83848 triosephosphate isomerase 1 BF116254 triosephosphate isomerase 1 TPI1 7167 NM_000365 /// NM_001159287 /// NM_001258026 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004807 // triose-phosphate isomerase activity // not recorded /// 0004807 // triose-phosphate isomerase activity // non-traceable author statement /// 0004807 // triose-phosphate isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 213012_at D42055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D42055.1 /DEF=Human mRNA for KIAA0093 gene, partial cds. /FEA=mRNA /GEN=KIAA0093 /DB_XREF=gi:577312 /UG=Hs.1565 neural precursor cell expressed, developmentally down-regulated 4 D42055 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase NEDD4 4734 NM_001284338 /// NM_001284339 /// NM_001284340 /// NM_006154 /// NM_198400 /// NR_104302 /// XR_243101 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002250 // adaptive immune response // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from electronic annotation /// 0006622 // protein targeting to lysosome // inferred from direct assay /// 0007041 // lysosomal transport // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010766 // negative regulation of sodium ion transport // inferred from direct assay /// 0010768 // negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019089 // transmission of virus // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from expression pattern /// 0031623 // receptor internalization // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype /// 0044111 // development involved in symbiotic interaction // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046824 // positive regulation of nucleocytoplasmic transport // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0051592 // response to calcium ion // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019871 // sodium channel inhibitor activity // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0050815 // phosphoserine binding // inferred from sequence or structural similarity /// 0050816 // phosphothreonine binding // inferred from sequence or structural similarity /// 0070063 // RNA polymerase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from mutant phenotype /// 0070064 // proline-rich region binding // inferred from physical interaction 213013_at BG164295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG164295 /FEA=EST /DB_XREF=gi:12670998 /DB_XREF=est:602341332F1 /CLONE=IMAGE:4449270 /UG=Hs.234249 mitogen-activated protein kinase 8 interacting protein 1 /FL=gb:AF074091.1 gb:NM_005456.1 BG164295 mitogen-activated protein kinase 8 interacting protein 1 pseudogene /// mitogen-activated protein kinase 8 interacting protein 1 LOC644172 /// MAPK8IP1 9479 /// 644172 NM_005456 /// NR_026901 /// XM_005253226 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007258 // JUN phosphorylation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044294 // dendritic growth cone // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044302 // dentate gyrus mossy fiber // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005078 // MAP-kinase scaffold activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 213014_at BG222394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG222394 /FEA=EST /DB_XREF=gi:12707915 /DB_XREF=est:naf75h09.x1 /CLONE=IMAGE:4170089 /UG=Hs.234249 mitogen-activated protein kinase 8 interacting protein 1 /FL=gb:AF074091.1 gb:NM_005456.1 BG222394 mitogen-activated protein kinase 8 interacting protein 1 MAPK8IP1 9479 NM_005456 /// XM_005253226 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007258 // JUN phosphorylation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044294 // dendritic growth cone // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044302 // dentate gyrus mossy fiber // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005078 // MAP-kinase scaffold activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 213015_at BF448315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448315 /FEA=EST /DB_XREF=gi:11513897 /DB_XREF=est:nad18a03.x1 /CLONE=IMAGE:3365668 /UG=Hs.152939 Homo sapiens clone 24630 mRNA sequence BF448315 bobby sox homolog (Drosophila) BBX 56987 NM_001142568 /// NM_001276286 /// NM_020235 /// XM_005247642 /// XM_005247643 /// XM_005247644 /// XM_005247645 /// XM_005247646 /// XM_006713706 /// XM_006713707 /// XM_006713708 /// XM_006713709 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 213016_at AA573805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA573805 /FEA=EST /DB_XREF=gi:2348320 /DB_XREF=est:nk07g11.s1 /CLONE=IMAGE:1012868 /UG=Hs.152939 Homo sapiens clone 24630 mRNA sequence AA573805 bobby sox homolog (Drosophila) BBX 56987 NM_001142568 /// NM_001276286 /// NM_020235 /// XM_005247642 /// XM_005247643 /// XM_005247644 /// XM_005247645 /// XM_005247646 /// XM_006713706 /// XM_006713707 /// XM_006713708 /// XM_006713709 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 213017_at AL534702 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL534702 /FEA=EST /DB_XREF=gi:12798195 /DB_XREF=est:AL534702 /CLONE=CS0DF006YN17 (3 prime) /UG=Hs.13377 Homo sapiens clone 23649 and 23755 unknown mRNA, partial cds AL534702 abhydrolase domain containing 3 ABHD3 171586 NM_138340 /// XR_243847 /// XR_430071 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 213018_at AI337901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI337901 /FEA=EST /DB_XREF=gi:4074828 /DB_XREF=est:qt34f05.x1 /CLONE=IMAGE:1949889 /UG=Hs.21145 hypothetical protein FLJ22489 AI337901 GATA zinc finger domain containing 1 GATAD1 57798 NM_021167 /// NR_052016 /// XR_428181 /// XR_428182 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213019_at AI123233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123233 /FEA=EST /DB_XREF=gi:3538999 /DB_XREF=est:qa47e04.x1 /CLONE=IMAGE:1689918 /UG=Hs.167496 RAN binding protein 6 AI123233 RAN binding protein 6 RANBP6 26953 NM_001243202 /// NM_001243203 /// NM_012416 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213020_at AI814252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814252 /FEA=EST /DB_XREF=gi:5425467 /DB_XREF=est:wj70g04.x1 /CLONE=IMAGE:2408214 /UG=Hs.194051 Homo sapiens mRNA; cDNA DKFZp566B213 (from clone DKFZp566B213) AI814252 golgi SNAP receptor complex member 1 GOSR1 9527 NM_001007024 /// NM_001007025 /// NM_004871 /// XM_005258070 /// XM_005258071 /// XM_005258072 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement 0005484 // SNAP receptor activity // inferred from direct assay 213021_at AI741876 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741876 /FEA=EST /DB_XREF=gi:5110251 /DB_XREF=est:wg48b05.x1 /CLONE=IMAGE:2368305 /UG=Hs.194051 Homo sapiens mRNA; cDNA DKFZp566B213 (from clone DKFZp566B213) AI741876 golgi SNAP receptor complex member 1 GOSR1 9527 NM_001007024 /// NM_001007025 /// NM_004871 /// XM_005258070 /// XM_005258071 /// XM_005258072 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement 0005484 // SNAP receptor activity // inferred from direct assay 213022_s_at NM_007124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007124.1 /DEF=Homo sapiens utrophin (homologous to dystrophin) (UTRN), mRNA. /FEA=CDS /GEN=UTRN /PROD=utrophin /DB_XREF=gi:6005937 /UG=Hs.251967 utrophin (homologous to dystrophin) /FL=gb:NM_007124.1 NM_007124 utrophin UTRN 7402 NM_007124 /// XM_005267127 /// XM_005267128 /// XM_005267130 /// XM_005267132 /// XM_005267133 /// XM_006715559 /// XM_006715560 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006936 // muscle contraction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070938 // contractile ring // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213023_at NM_007124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007124.1 /DEF=Homo sapiens utrophin (homologous to dystrophin) (UTRN), mRNA. /FEA=CDS /GEN=UTRN /PROD=utrophin /DB_XREF=gi:6005937 /UG=Hs.251967 utrophin (homologous to dystrophin) /FL=gb:NM_007124.1 NM_007124 utrophin UTRN 7402 NM_007124 /// XM_005267127 /// XM_005267128 /// XM_005267130 /// XM_005267132 /// XM_005267133 /// XM_006715559 /// XM_006715560 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006936 // muscle contraction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070938 // contractile ring // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213024_at BF593908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593908 /FEA=EST /DB_XREF=gi:11686232 /DB_XREF=est:nab48b03.x1 /CLONE=IMAGE:3268948 /UG=Hs.267632 TATA element modulatory factor 1 /FL=gb:L01042.1 gb:NM_007114.1 BF593908 TATA element modulatory factor 1 TMF1 7110 NM_007114 0001675 // acrosome assembly // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0032275 // luteinizing hormone secretion // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2000845 // positive regulation of testosterone secretion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213025_at AL134904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134904 /FEA=EST /DB_XREF=gi:6603091 /DB_XREF=est:DKFZp762M0710_s1 /CLONE=DKFZp762M0710 /UG=Hs.268371 hypothetical protein FLJ20274 AL134904 THUMP domain containing 1 THUMPD1 55623 NM_017736 /// XM_005255422 /// XM_005255424 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213026_at BE965998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965998 /FEA=EST /DB_XREF=gi:11770950 /DB_XREF=est:601659892R1 /CLONE=IMAGE:3905710 /UG=Hs.264482 Apg12 (autophagy 12, S. cerevisiae)-like BE965998 autophagy related 12 ATG12 9140 NM_001277783 /// NM_004707 /// NR_033362 /// NR_033363 /// NR_073603 /// NR_073604 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // /// 0002376 // immune system process // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0044804 // nucleophagy // /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // 213027_at AU146655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146655 /FEA=EST /DB_XREF=gi:11008176 /DB_XREF=est:AU146655 /CLONE=HEMBB1001133 /UG=Hs.288178 Homo sapiens cDNA FLJ11968 fis, clone HEMBB1001133 AU146655 Homo sapiens RNA, has-miR-mizuguchi-9, complete sequence. /// TROVE domain family, member 2 AK022030 /// TROVE2 6738 NM_001042369 /// NM_001042370 /// NM_001173524 /// NM_001173525 /// NM_004600 /// NR_033393 /// XM_006711495 /// XM_006711496 /// XM_006711497 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213028_at AI887378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI887378 /FEA=EST /DB_XREF=gi:5592542 /DB_XREF=est:wm39f04.x1 /CLONE=IMAGE:2438335 /UG=Hs.282441 nuclear factor related to kappa B binding protein AI887378 nuclear factor related to kappaB binding protein NFRKB 4798 NM_001143835 /// NM_006165 /// XM_005271565 /// XM_005271566 /// XM_005271567 /// XM_005271568 /// XM_005271569 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213029_at BG478428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG478428 /FEA=EST /DB_XREF=gi:13410807 /DB_XREF=est:602523839F1 /CLONE=IMAGE:4642353 /UG=Hs.326416 Homo sapiens mRNA; cDNA DKFZp564H1916 (from clone DKFZp564H1916) BG478428 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 213030_s_at AI688418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688418 /FEA=EST /DB_XREF=gi:4899712 /DB_XREF=est:wc94h03.x1 /CLONE=IMAGE:2326325 /UG=Hs.300622 plexin A2 AI688418 plexin A2 PLXNA2 5362 NM_025179 /// XM_005273164 /// XM_005273165 /// XM_006711387 0001756 // somitogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0021915 // neural tube development // inferred from electronic annotation /// 0021935 // cerebellar granule cell precursor tangential migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity 213031_s_at AF161382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161382.1 /DEF=Homo sapiens HSPC264 mRNA, partial cds. /FEA=mRNA /PROD=HSPC264 /DB_XREF=gi:6841177 /UG=Hs.29863 Homo sapiens HSPC264 mRNA, partial cds AF161382 WD repeat domain 73 WDR73 84942 NM_032856 /// XM_005254983 /// XM_006720724 /// XR_243214 /// XR_243215 0005515 // protein binding // inferred from electronic annotation 213032_at AI186739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186739 /FEA=EST /DB_XREF=gi:3737377 /DB_XREF=est:qe79c01.x1 /CLONE=IMAGE:1745184 /UG=Hs.326416 Homo sapiens mRNA; cDNA DKFZp564H1916 (from clone DKFZp564H1916) AI186739 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 213033_s_at AI186739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186739 /FEA=EST /DB_XREF=gi:3737377 /DB_XREF=est:qe79c01.x1 /CLONE=IMAGE:1745184 /UG=Hs.326416 Homo sapiens mRNA; cDNA DKFZp564H1916 (from clone DKFZp564H1916) AI186739 nuclear factor I/B NFIB 4781 NM_001190737 /// NM_001190738 /// NM_001282787 /// NM_005596 /// XM_005251467 /// XM_005251468 /// XM_005251469 /// XM_005251470 /// XM_005251471 /// XM_006716773 /// XM_006716774 /// XM_006716775 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from sequence or structural similarity /// 0021740 // principal sensory nucleus of trigeminal nerve development // inferred from sequence or structural similarity /// 0021960 // anterior commissure morphogenesis // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060486 // Clara cell differentiation // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from sequence or structural similarity /// 0061141 // lung ciliated cell differentiation // inferred from sequence or structural similarity /// 0071679 // commissural neuron axon guidance // inferred from sequence or structural similarity /// 2000791 // negative regulation of mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 2000795 // negative regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0044300 // cerebellar mossy fiber // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 213034_at AB023216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023216.1 /DEF=Homo sapiens mRNA for KIAA0999 protein, partial cds. /FEA=mRNA /GEN=KIAA0999 /PROD=KIAA0999 protein /DB_XREF=gi:4589641 /UG=Hs.4278 KIAA0999 protein AB023216 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213035_at AI081194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI081194 /FEA=EST /DB_XREF=gi:3417986 /DB_XREF=est:ox76a08.x1 /CLONE=IMAGE:1662230 /UG=Hs.32556 KIAA0379 protein AI081194 ankyrin repeat domain 28 ANKRD28 23243 NM_001195098 /// NM_001195099 /// NM_015199 /// XM_005264996 /// XM_005264997 /// XM_005264998 /// XM_006713074 /// XM_006713075 /// XM_006713076 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213036_x_at Y15724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15724 /DEF=Homo sapiens SERCA3 gene, exons 1-7 (and joined CDS) /FEA=mRNA /DB_XREF=gi:3021395 /UG=Hs.5541 ATPase, Ca++ transporting, ubiquitous Y15724 ATPase, Ca++ transporting, ubiquitous ATP2A3 489 NM_005173 /// NM_174953 /// NM_174954 /// NM_174955 /// NM_174956 /// NM_174957 /// NM_174958 /// XM_005256656 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213037_x_at AJ132258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ132258.1 /DEF=Homo sapiens mRNA for staufen protein, partial. /FEA=mRNA /GEN=staufen /PROD=staufen protein /DB_XREF=gi:4572587 /UG=Hs.6113 staufen (Drosophila, RNA-binding protein) AJ132258 staufen double-stranded RNA binding protein 1 STAU1 6780 NM_001037328 /// NM_004602 /// NM_017452 /// NM_017453 /// NM_017454 /// XM_005260524 /// XM_005260525 /// XM_005260526 /// XM_005260527 /// XM_005260528 /// XM_005260529 /// XM_006723865 /// XM_006723866 /// XM_006723867 /// XM_006723868 /// XM_006723869 0008298 // intracellular mRNA localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008157 // protein phosphatase 1 binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213038_at AL031602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031602 /DEF=Human DNA sequence from clone RP5-1174N9 on chromosome 1p34.1-35.3. Contains the gene for a novel protein with IBR domain, a (pseudo?) gene for a novel protein similar to MT1E (metallothionein 1E (functional)), ESTs, STSs, GSSs and two putative Cp... /FEA=mRNA_2 /DB_XREF=gi:6729581 /UG=Hs.64239 Human DNA sequence from clone RP5-1174N9 on chromosome 1p34.1-35.3. Contains the gene for a novel protein with IBR domain, a (pseudo?) gene for a novel protein similar to MT1E (metallothionein 1E (functional)), ESTs, STSs, GSSs and two putative CpG island AL031602 ring finger protein 19B RNF19B 127544 NM_001127361 /// NM_153341 /// XM_005270460 /// XM_006710356 /// XM_006710357 /// XM_006710358 0002376 // immune system process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213039_at AB011093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011093.1 /DEF=Homo sapiens mRNA for KIAA0521 protein, partial cds. /FEA=mRNA /GEN=KIAA0521 /PROD=KIAA0521 protein /DB_XREF=gi:3043565 /UG=Hs.6150 Rho-specific guanine nucleotide exchange factor p114 AB011093 Rho/Rac guanine nucleotide exchange factor (GEF) 18 ARHGEF18 23370 NM_001130955 /// NM_015318 /// XM_005272464 /// XM_005272465 /// XM_006722705 /// XM_006722706 /// XM_006722707 /// XM_006722708 /// XM_006722709 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0045177 // apical part of cell // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 213040_s_at AL008583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL008583 /DEF=Human DNA sequence from clone RP3-327J16 on chromosome 22q12.3-13.2 Contains the DNAL4 gene for axonemal dynein light polypeptide 4, the NPTXR gene for neuronal pentraxin receptor and the CBX6 gene for chromobox homolog 6. Contains ESTs, STSs, a G... /FEA=mRNA_2 /DB_XREF=gi:4160195 /UG=Hs.91622 neuronal pentraxin receptor /FL=gb:NM_014293.1 AL008583 neuronal pentraxin receptor NPTXR 23467 NM_014293 /// NM_058178 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 213041_s_at BE798517 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE798517 /FEA=EST /DB_XREF=gi:10219715 /DB_XREF=est:601583226F1 /CLONE=IMAGE:3937495 /UG=Hs.89761 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit BE798517 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit ATP5D 513 NM_001001975 /// NM_001687 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // non-traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046688 // response to copper ion // non-traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0043531 // ADP binding // non-traceable author statement /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 213042_s_at AA877910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA877910 /FEA=EST /DB_XREF=gi:2986875 /DB_XREF=est:nr12h12.s1 /CLONE=IMAGE:1161671 /UG=Hs.5541 ATPase, Ca++ transporting, ubiquitous AA877910 ATPase, Ca++ transporting, ubiquitous ATP2A3 489 NM_005173 /// NM_174953 /// NM_174954 /// NM_174955 /// NM_174956 /// NM_174957 /// NM_174958 /// XM_005256656 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213043_s_at AI023317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI023317 /FEA=EST /DB_XREF=gi:3239723 /DB_XREF=est:ox04a05.x1 /CLONE=IMAGE:1655312 /UG=Hs.23106 KIAA0130 gene product AI023317 mediator complex subunit 24 /// microRNA 6884 MED24 /// MIR6884 9862 /// 102466757 NM_001079518 /// NM_001267797 /// NM_014815 /// NR_052017 /// NR_106944 /// XM_005257870 /// XM_005257871 /// XM_005257872 /// XM_005257873 /// XM_005257874 /// XM_006722203 /// XM_006722204 /// XM_006722205 /// XM_006722206 /// XM_006722207 /// XR_429934 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // non-traceable author statement 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 213044_at N22548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N22548 /FEA=EST /DB_XREF=gi:1128682 /DB_XREF=est:yw30c06.s1 /CLONE=IMAGE:253738 /UG=Hs.17820 Rho-associated, coiled-coil containing protein kinase 1 N22548 Rho-associated, coiled-coil containing protein kinase 1 ROCK1 6093 NM_005406 0003383 // apical constriction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006939 // smooth muscle contraction // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0022614 // membrane to membrane docking // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // traceable author statement /// 0032060 // bleb assembly // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045616 // regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from direct assay /// 0050901 // leukocyte tethering or rolling // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 2000114 // regulation of establishment of cell polarity // traceable author statement /// 2000145 // regulation of cell motility // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213045_at AB011133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011133.1 /DEF=Homo sapiens mRNA for KIAA0561 protein, partial cds. /FEA=mRNA /GEN=KIAA0561 /PROD=KIAA0561 protein /DB_XREF=gi:3043645 /UG=Hs.173864 KIAA0561 protein AB011133 microtubule associated serine/threonine kinase 3 MAST3 23031 NM_015016 /// XM_005259822 /// XM_005259823 /// XM_005259824 /// XM_005259825 /// XM_005259826 /// XM_005259827 /// XM_005259828 /// XM_006722693 /// XM_006722694 /// XM_006722695 /// XM_006722696 /// XM_006722697 /// XM_006722698 /// XM_006722699 /// XM_006722700 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213046_at AI130920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI130920 /FEA=EST /DB_XREF=gi:3600936 /DB_XREF=est:qb81h08.x1 /CLONE=IMAGE:1706559 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 AI130920 poly(A) binding protein, nuclear 1 PABPN1 8106 NM_004643 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0046778 // modification by virus of host mRNA processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213047_x_at AI278616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI278616 /FEA=EST /DB_XREF=gi:3916850 /DB_XREF=est:qm47a06.x1 /CLONE=IMAGE:1891858 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) AI278616 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 213048_s_at W26593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W26593 /FEA=EST /DB_XREF=gi:1307454 /DB_XREF=est:33g5 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) W26593 Homo sapiens mRNA from HIV associated non-Hodgkins lymphoma (clone hl1-98). Y16709 213049_at BG436400 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG436400 /FEA=EST /DB_XREF=gi:13342906 /DB_XREF=est:602509062F1 /CLONE=IMAGE:4619679 /UG=Hs.167031 DKFZP566D133 protein BG436400 Ral GTPase activating protein, alpha subunit 1 (catalytic) RALGAPA1 253959 NM_001283043 /// NM_001283044 /// NM_014990 /// NM_194301 /// XM_005267491 /// XM_005267492 /// XM_005267493 /// XM_005267498 /// XM_006720098 /// XM_006720099 /// XM_006720100 /// XM_006720101 /// XM_006720102 /// XM_006720103 /// XM_006720104 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // not recorded /// 0032859 // activation of Ral GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // /// 0005488 // binding // inferred from electronic annotation /// 0017123 // Ral GTPase activator activity // not recorded /// 0017123 // Ral GTPase activator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction 213050_at AA594937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA594937 /FEA=EST /DB_XREF=gi:2410287 /DB_XREF=est:no40b03.s1 /CLONE=IMAGE:1103117 /UG=Hs.33010 KIAA0633 protein AA594937 cordon-bleu WH2 repeat protein COBL 23242 NM_001287436 /// NM_001287438 /// NM_015198 /// XM_005271750 /// XM_005271751 /// XM_005271752 /// XM_005271753 /// XM_005271755 /// XM_005271756 /// XM_005271757 /// XM_006715675 0000578 // embryonic axis specification // inferred from sequence or structural similarity /// 0001757 // somite specification // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030903 // notochord development // inferred from sequence or structural similarity /// 0033504 // floor plate development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048669 // collateral sprouting in absence of injury // inferred from sequence or structural similarity /// 0051639 // actin filament network formation // inferred from sequence or structural similarity /// 1900006 // positive regulation of dendrite development // inferred from sequence or structural similarity 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044294 // dendritic growth cone // inferred from sequence or structural similarity /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 213051_at AI133727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI133727 /FEA=EST /DB_XREF=gi:3602925 /DB_XREF=est:Habcs0217 /UG=Hs.35254 hypothetical protein FLB6421 AI133727 zinc finger CCCH-type, antiviral 1 ZC3HAV1 56829 NM_020119 /// NM_024625 /// XM_005250501 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0061014 // positive regulation of mRNA catabolic process // inferred from direct assay /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213052_at BF246917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF246917 /FEA=EST /DB_XREF=gi:11161763 /DB_XREF=est:601854275F1 /CLONE=IMAGE:4074234 /UG=Hs.289075 protein kinase, cAMP-dependent, regulatory, type II, alpha BF246917 protein kinase, cAMP-dependent, regulatory, type II, alpha PRKAR2A 5576 NM_004157 /// XM_005265313 /// XM_005265314 /// XM_005265315 /// XR_427280 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 213053_at AW189966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW189966 /FEA=EST /DB_XREF=gi:6464446 /DB_XREF=est:xl10g04.x1 /CLONE=IMAGE:2675862 /UG=Hs.7426 KIAA0841 protein AW189966 HAUS augmin-like complex, subunit 5 HAUS5 23354 NM_015302 /// XM_006723119 /// XR_243915 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 213054_at AA845355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA845355 /FEA=EST /DB_XREF=gi:2933114 /DB_XREF=est:ak01g08.s1 /CLONE=IMAGE:1404734 /UG=Hs.7426 KIAA0841 protein AA845355 HAUS augmin-like complex, subunit 5 HAUS5 23354 NM_015302 /// XM_006723119 /// XR_243915 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 213055_at BF693956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF693956 /FEA=EST /DB_XREF=gi:11979364 /DB_XREF=est:602082535F1 /CLONE=IMAGE:4246664 /UG=Hs.82685 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) BF693956 CD47 molecule CD47 961 NM_001025079 /// NM_001025080 /// NM_001777 /// NM_198793 /// XM_005247908 /// XM_005247909 /// XR_241521 /// XR_241522 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008228 // opsonization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009617 // response to bacterium // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0070053 // thrombospondin receptor activity // inferred from physical interaction 213056_at AU145019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145019 /FEA=EST /DB_XREF=gi:11006540 /DB_XREF=est:AU145019 /CLONE=HEMBA1003646 /UG=Hs.96427 KIAA1013 protein AU145019 FERM domain containing 4B FRMD4B 23150 NM_015123 /// XM_005264720 /// XM_005264721 /// XM_005264722 /// XM_005264723 /// XM_006713063 /// XM_006713064 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213057_at AW118608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW118608 /FEA=EST /DB_XREF=gi:6087192 /DB_XREF=est:xd94e03.x1 /CLONE=IMAGE:2605276 /UG=Hs.13434 Homo sapiens clone 24418 mRNA sequence AW118608 ATP synthase mitochondrial F1 complex assembly factor 2 ATPAF2 91647 NM_145691 /// XM_005256848 0043461 // proton-transporting ATP synthase complex assembly // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213058_at AL033538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL033538 /DEF=Human DNA sequence from clone RP3-477H23 on chromosome 22q12.1-12.2 Contains parts of one or two novel genes, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:4165236 /UG=Hs.11390 KIAA1043 protein AL033538 tetratricopeptide repeat domain 28 TTC28 23331 NM_001145418 /// NM_015281 /// XM_005261405 /// XM_006724171 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213059_at AF055009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055009.1 /DEF=Homo sapiens clone 24747 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005731 /UG=Hs.13456 Homo sapiens clone 24747 mRNA sequence AF055009 cAMP responsive element binding protein 3-like 1 CREB3L1 90993 NM_052854 /// XM_006718380 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213060_s_at U58515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U58515.1 /DEF=Human chitinase (HUMTCHIT) mRNA, exon 1b form, partial cds. /FEA=mRNA /GEN=HUMTCHIT /PROD=chitinase /DB_XREF=gi:1439567 /UG=Hs.154138 chitinase 3-like 2 U58515 chitinase 3-like 2 CHI3L2 1117 NM_001025197 /// NM_001025199 /// NM_004000 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0008061 // chitin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 213061_s_at AA643304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA643304 /FEA=EST /DB_XREF=gi:2568522 /DB_XREF=est:nr59a09.s1 /CLONE=IMAGE:1172248 /UG=Hs.170218 KIAA0251 protein AA643304 N-terminal asparagine amidase NTAN1 123803 NM_001270766 /// NM_001270767 /// NM_173474 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008418 // protein-N-terminal asparagine amidohydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213062_at AA643304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA643304 /FEA=EST /DB_XREF=gi:2568522 /DB_XREF=est:nr59a09.s1 /CLONE=IMAGE:1172248 /UG=Hs.170218 KIAA0251 protein AA643304 N-terminal asparagine amidase NTAN1 123803 NM_001270766 /// NM_001270767 /// NM_173474 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008418 // protein-N-terminal asparagine amidohydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213063_at BF970253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF970253 /FEA=EST /DB_XREF=gi:12337468 /DB_XREF=est:602273505F1 /CLONE=IMAGE:4361569 /UG=Hs.173684 Homo sapiens mRNA; cDNA DKFZp762G207 (from clone DKFZp762G207) BF970253 zinc finger CCCH-type containing 14 ZC3H14 79882 NM_001160103 /// NM_001160104 /// NM_024824 /// NM_207660 /// NM_207661 /// NM_207662 /// XM_005268067 /// XM_005268068 /// XM_005268069 /// XM_005268070 /// XM_005268071 /// XM_005268073 /// XM_006720257 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213064_at N64802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64802 /FEA=EST /DB_XREF=gi:1212631 /DB_XREF=est:yz31b05.s1 /CLONE=IMAGE:284625 /UG=Hs.173684 Homo sapiens mRNA; cDNA DKFZp762G207 (from clone DKFZp762G207) N64802 zinc finger CCCH-type containing 14 ZC3H14 79882 NM_001160103 /// NM_001160104 /// NM_024824 /// NM_207660 /// NM_207661 /// NM_207662 /// XM_005268067 /// XM_005268068 /// XM_005268069 /// XM_005268070 /// XM_005268071 /// XM_005268073 /// XM_006720257 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213065_at AB011118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011118.1 /DEF=Homo sapiens mRNA for KIAA0546 protein, partial cds. /FEA=mRNA /GEN=KIAA0546 /PROD=KIAA0546 protein /DB_XREF=gi:3043615 /UG=Hs.26764 KIAA0546 protein AB011118 zinc finger, C3H1-type containing ZFC3H1 196441 NM_144982 0006396 // RNA processing // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213066_at AB002373 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002373.2 /DEF=Homo sapiens mRNA for KIAA0375 protein, partial cds. /FEA=mRNA /GEN=KIAA0375 /PROD=KIAA0375 protein /DB_XREF=gi:6683646 /UG=Hs.26951 KIAA0375 gene product AB002373 RUN and SH3 domain containing 2 RUSC2 9853 NM_001135999 /// NM_014806 /// NR_052015 /// XM_006716896 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction 213067_at AI382123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI382123 /FEA=EST /DB_XREF=gi:4194904 /DB_XREF=est:te30a09.x1 /CLONE=IMAGE:2087416 /UG=Hs.182919 ESTs, Highly similar to A59252 myosin heavy chain, nonmuscle, form IIB H.sapiens AI382123 myosin, heavy chain 10, non-muscle MYH10 4628 NM_001256012 /// NM_001256095 /// NM_005964 /// XM_005256651 /// XM_005256652 /// XM_005256653 0000281 // mitotic cytokinesis // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001778 // plasma membrane repair // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006887 // exocytosis // inferred from electronic annotation /// 0006930 // substrate-dependent cell migration, cell extension // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0021592 // fourth ventricle development // inferred from electronic annotation /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0021678 // third ventricle development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0030239 // myofibril assembly // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016459 // myosin complex // non-traceable author statement /// 0016460 // myosin II complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0042641 // actomyosin // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // non-traceable author statement /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from mutant phenotype /// 0043531 // ADP binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from mutant phenotype 213068_at AI146848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI146848 /FEA=EST /DB_XREF=gi:3674530 /DB_XREF=est:qb92h06.x1 /CLONE=IMAGE:1707611 /UG=Hs.80552 dermatopontin AI146848 dermatopontin DPT 1805 NM_001937 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 213069_at AI148659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI148659 /FEA=EST /DB_XREF=gi:3677128 /DB_XREF=est:qc69c01.x1 /CLONE=IMAGE:1714848 /UG=Hs.296326 ESTs AI148659 heart development protein with EGF-like domains 1 HEG1 57493 NM_020733 /// XM_005247666 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0003017 // lymph circulation // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0048845 // venous blood vessel morphogenesis // inferred from electronic annotation /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213070_at AV682436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV682436 /FEA=EST /DB_XREF=gi:10284299 /DB_XREF=est:AV682436 /CLONE=GKBABE08 /UG=Hs.5848 Homo sapiens mRNA; cDNA DKFZp564L222 (from clone DKFZp564L222) AV682436 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha PIK3C2A 5286 NM_002645 /// XM_005252977 /// XM_005252978 /// XM_005252979 /// XM_005252980 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006887 // exocytosis // traceable author statement /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0014829 // vascular smooth muscle contraction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0048268 // clathrin coat assembly // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 213071_at AL049798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049798 /DEF=Human DNA sequence from clone 797M17 on chromosome 1q22-24.3. Contains the DPT gene for Dermatopontin, ESTs, an STS and GSSs /FEA=mRNA /DB_XREF=gi:4995638 /UG=Hs.80552 dermatopontin AL049798 dermatopontin DPT 1805 NM_001937 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 213072_at AI928387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI928387 /FEA=EST /DB_XREF=gi:5664351 /DB_XREF=est:wo96f10.x1 /CLONE=IMAGE:2463211 /UG=Hs.331601 Homo sapiens, Similar to cysteine and histidine-rich protein, clone IMAGE:3945559, mRNA, partial cds AI928387 cysteine/histidine-rich 1 CYHR1 50626 NM_001129888 /// NM_032687 /// NM_138496 /// XM_006716560 /// XM_006716561 /// XM_006716562 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213073_at AB002319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002319.1 /DEF=Human mRNA for KIAA0321 gene, partial cds. /FEA=mRNA /GEN=KIAA0321 /DB_XREF=gi:2224582 /UG=Hs.8663 KIAA0321 protein AB002319 zinc finger, FYVE domain containing 26 ZFYVE26 23503 NM_015346 /// XM_006720093 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213074_at BG545769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG545769 /FEA=EST /DB_XREF=gi:13544434 /DB_XREF=est:602573042F1 /CLONE=IMAGE:4701250 /UG=Hs.9927 Homo sapiens mRNA; cDNA DKFZp564D156 (from clone DKFZp564D156) BG545769 pleckstrin homology domain interacting protein PHIP 55023 NM_017934 /// XM_005248729 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005158 // insulin receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 213075_at AL050002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050002.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564O222 (from clone DKFZp564O222). /FEA=mRNA /DB_XREF=gi:4884256 /UG=Hs.94795 Homo sapiens mRNA; cDNA DKFZp564O222 (from clone DKFZp564O222) AL050002 olfactomedin-like 2A OLFML2A 169611 NM_001282715 /// NM_182487 /// XM_005251759 /// XM_005251760 /// XM_006716989 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 213076_at D38169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38169.1 /DEF=Homo sapiens mRNA for inositol 1,4,5-trisphosphate 3-kinase isoenzyme, partial cds. /FEA=mRNA /PROD=inositol 1,4,5-trisphosphate 3-kinase isoenzyme /DB_XREF=gi:2463541 /UG=Hs.21453 inositol 1,4,5-trisphosphate 3-kinase C D38169 inositol-trisphosphate 3-kinase C ITPKC 80271 NM_025194 /// XM_006723404 /// XR_243961 0016310 // phosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213077_at AL049305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049305.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A186 (from clone DKFZp564A186). /FEA=mRNA /DB_XREF=gi:4500074 /UG=Hs.104916 hypothetical protein FLJ21940 AL049305 YTH domain containing 2 YTHDC2 64848 NM_022828 /// XM_005272052 /// XR_246540 0006200 // ATP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0044829 // positive regulation by host of viral genome replication // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from physical interaction 213078_x_at AI889513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI889513 /FEA=EST /DB_XREF=gi:5594677 /DB_XREF=est:wn05e06.x1 /CLONE=IMAGE:2444578 /UG=Hs.168694 Homo sapiens clone 23763 unknown mRNA, partial cds AI889513 lysophosphatidylcholine acyltransferase 4 LPCAT4 254531 NM_153613 /// XM_006720454 /// XR_243087 /// XR_243088 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047166 // 1-alkenylglycerophosphoethanolamine O-acyltransferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047192 // 1-alkylglycerophosphocholine O-acetyltransferase activity // inferred from electronic annotation /// 0071617 // lysophospholipid acyltransferase activity // inferred from direct assay /// 0071617 // lysophospholipid acyltransferase activity // inferred from mutant phenotype 213079_at AA223871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA223871 /FEA=EST /DB_XREF=gi:1844456 /DB_XREF=est:zr13a02.s1 /CLONE=IMAGE:648650 /UG=Hs.178207 Homo sapiens clone DT1P1A10 mRNA, CAG repeat region AA223871 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) TSR2 90121 NM_058163 0006364 // rRNA processing // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213080_x_at BF214492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF214492 /FEA=EST /DB_XREF=gi:11108078 /DB_XREF=est:601845736F1 /CLONE=IMAGE:4076600 /UG=Hs.180946 ribosomal protein L5 BF214492 ribosomal protein L5 /// small nucleolar RNA, C/D box 21 RPL5 /// SNORD21 6083 /// 6125 NM_000969 /// NR_000006 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213081_at AL523144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523144 /FEA=EST /DB_XREF=gi:12786637 /DB_XREF=est:AL523144 /CLONE=CS0DC001YO14 (3 prime) /UG=Hs.206770 zinc finger protein 297 /FL=gb:NM_005453.2 AL523144 zinc finger and BTB domain containing 22 ZBTB22 9278 NM_001145338 /// NM_005453 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213082_s_at AJ005866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ005866.1 /DEF=Homo sapiens mRNA for putative Sqv-7-like protein, partial. /FEA=mRNA /PROD=Sqv-7-like protein /DB_XREF=gi:4008516 /UG=Hs.90078 nucleotide-sugar transporter similar to C. elegans sqv-7 AJ005866 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 SLC35D2 11046 NM_001286990 /// NM_007001 /// NR_104627 /// XM_005251673 /// XM_005251674 /// XM_005251675 /// XM_005251676 /// XM_005251678 /// XM_006716939 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901264 // carbohydrate derivative transport // non-traceable author statement /// 1901679 // nucleotide transmembrane transport // non-traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // non-traceable author statement 213083_at AJ005866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ005866.1 /DEF=Homo sapiens mRNA for putative Sqv-7-like protein, partial. /FEA=mRNA /PROD=Sqv-7-like protein /DB_XREF=gi:4008516 /UG=Hs.90078 nucleotide-sugar transporter similar to C. elegans sqv-7 AJ005866 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 SLC35D2 11046 NM_001286990 /// NM_007001 /// NR_104627 /// XM_005251673 /// XM_005251674 /// XM_005251675 /// XM_005251676 /// XM_005251678 /// XM_006716939 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901264 // carbohydrate derivative transport // non-traceable author statement /// 1901679 // nucleotide transmembrane transport // non-traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // non-traceable author statement 213084_x_at BF125158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF125158 /FEA=EST /DB_XREF=gi:10964198 /DB_XREF=est:601762392F1 /CLONE=IMAGE:4025158 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) BF125158 ribosomal protein L23a /// small nucleolar RNA, C/D box 42A RPL23A /// SNORD42A 6147 /// 26809 NM_000984 /// NR_000014 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213085_s_at AB020676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020676.1 /DEF=Homo sapiens mRNA for KIAA0869 protein, partial cds. /FEA=mRNA /GEN=KIAA0869 /PROD=KIAA0869 protein /DB_XREF=gi:4240226 /UG=Hs.21543 KIAA0869 protein AB020676 WW and C2 domain containing 1 WWC1 23286 NM_001161661 /// NM_001161662 /// NM_015238 /// XM_005265850 /// XM_005265851 /// XM_005265852 /// XM_005265853 /// XM_006714835 /// XM_006714836 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0032386 // regulation of intracellular transport // traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay 213086_s_at BF341845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF341845 /FEA=EST /DB_XREF=gi:11288369 /DB_XREF=est:602016378F1 /CLONE=IMAGE:4151970 /UG=Hs.84264 acidic protein rich in leucines BF341845 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213087_s_at BF690020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF690020 /FEA=EST /DB_XREF=gi:11975428 /DB_XREF=est:602186310T1 /CLONE=IMAGE:4298426 /UG=Hs.223241 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) BF690020 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) EEF1D 1936 NM_001130053 /// NM_001130054 /// NM_001130055 /// NM_001130056 /// NM_001130057 /// NM_001195203 /// NM_001289950 /// NM_001960 /// NM_032378 /// XM_005250820 /// XM_005250821 /// XM_005250823 /// XM_005250824 /// XM_005250825 /// XM_005250826 /// XM_006716519 /// XM_006716520 /// XM_006716521 /// XM_006716522 /// XM_006716523 /// XM_006716524 /// XM_006716525 /// XM_006725064 /// XM_006725065 /// XM_006725066 /// XM_006725067 /// XM_006725068 /// XM_006725069 /// XM_006725070 /// XM_006725071 /// XM_006725072 /// XM_006725073 /// XM_006725074 /// XM_006725075 /// XM_006725076 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 213088_s_at BE551340 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551340 /FEA=EST /DB_XREF=gi:9793032 /DB_XREF=est:7b63c12.x1 /CLONE=IMAGE:3232918 /UG=Hs.44131 KIAA0974 protein BE551340 DnaJ (Hsp40) homolog, subfamily C, member 9 DNAJC9 23234 NM_015190 /// XM_006717734 0006412 // translation // inferred from electronic annotation /// 0035176 // social behavior // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 213089_at AU158490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158490 /FEA=EST /DB_XREF=gi:11020011 /DB_XREF=est:AU158490 /CLONE=PLACE3000042 /UG=Hs.303632 Human DNA sequence from clone RP11-110H4 on chromosome 5 Contains a pseudogene similar to GUSB (glucuronidase, beta), a gene for a membrane protein, ESTs, STSs, GSSs and CpG islands AU158490 uncharacterized LOC100272216 LOC100272216 100272216 NR_027439 213090_s_at AI744029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744029 /FEA=EST /DB_XREF=gi:5112317 /DB_XREF=est:wc32h02.x1 /CLONE=IMAGE:2316915 /UG=Hs.24644 TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD AI744029 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa TAF4 6874 NM_003185 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213091_at AB014516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014516.1 /DEF=Homo sapiens mRNA for KIAA0616 protein, partial cds. /FEA=mRNA /GEN=KIAA0616 /PROD=KIAA0616 protein /DB_XREF=gi:3327045 /UG=Hs.6051 KIAA0616 protein AB014516 CREB regulated transcription coactivator 1 CRTC1 23373 NM_001098482 /// NM_015321 /// NM_025021 /// XM_005259833 /// XM_005259834 /// XM_005259835 /// XM_005259836 /// XM_006722710 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // inferred from direct assay 213092_x_at AW241779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW241779 /FEA=EST /DB_XREF=gi:6575533 /DB_XREF=est:xn75a03.x1 /CLONE=IMAGE:2700268 /UG=Hs.44131 KIAA0974 protein AW241779 DnaJ (Hsp40) homolog, subfamily C, member 9 DNAJC9 23234 NM_015190 /// XM_006717734 0006412 // translation // inferred from electronic annotation /// 0035176 // social behavior // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 213093_at AI471375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI471375 /FEA=EST /DB_XREF=gi:4333465 /DB_XREF=est:tm10c12.x1 /CLONE=IMAGE:2156182 /UG=Hs.80206 glucose-6-phosphate dehydrogenase AI471375 protein kinase C, alpha PRKCA 5578 NM_002737 /// XM_006721972 /// XR_243672 /// XR_243673 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from mutant phenotype /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006739 // NADP metabolic process // inferred from direct assay /// 0006740 // NADPH regeneration // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from electronic annotation /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0010734 // negative regulation of protein glutathionylation // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019322 // pentose biosynthetic process // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032094 // response to food // inferred from electronic annotation /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0036289 // peptidyl-serine autophosphorylation // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from mutant phenotype /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046390 // ribose phosphate biosynthetic process // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // inferred from direct assay /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation /// 0090330 // regulation of platelet aggregation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2000707 // positive regulation of dense core granule biogenesis // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from direct assay /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from electronic annotation /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from mutant phenotype /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004698 // calcium-dependent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005536 // glucose binding // inferred from direct assay /// 0005536 // glucose binding // inferred from electronic annotation /// 0005536 // glucose binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0050661 // NADP binding // inferred from electronic annotation 213094_at AL033377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL033377 /DEF=Human DNA sequence from clone 287G14 on chromosome 6q23.1-24.3. Contains a novel seven transmembrane domain protein gene, and an exon similar to parts of BMP and Tolloid genes. Contains ESTs, an STS and GSSs /FEA=mRNA_3 /DB_XREF=gi:4826462 /UG=Hs.44197 hypothetical protein DKFZp564D0462 AL033377 G protein-coupled receptor 126 GPR126 57211 NM_001032394 /// NM_001032395 /// NM_020455 /// NM_198569 /// XM_005267061 /// XM_006715516 /// XM_006715517 /// XM_006715518 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 213095_x_at AF299327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF299327.1 /DEF=Homo sapiens allograft inflammatory factor-1 splice variant G1 mRNA, complete cds. /FEA=CDS /PROD=allograft inflammatory factor-1 splice variantG1 /DB_XREF=gi:11611961 /UG=Hs.76364 allograft inflammatory factor 1 /FL=gb:AF299327.1 AF299327 allograft inflammatory factor 1 AIF1 199 NM_001623 /// NM_004847 /// NM_032955 /// XM_005248869 /// XM_005248870 /// XM_005248871 /// XM_005272777 /// XM_005272778 /// XM_005272779 /// XM_005274923 /// XM_005274924 /// XM_005274925 /// XM_005275219 /// XM_005275220 /// XM_005275221 /// XM_005275355 /// XM_005275356 /// XM_005275357 /// XM_005275514 /// XM_005275515 /// XM_005275516 0001774 // microglial cell activation // non-traceable author statement /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006954 // inflammatory response // non-traceable author statement /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030041 // actin filament polymerization // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from sequence or structural similarity /// 0071672 // negative regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0097178 // ruffle assembly // inferred from sequence or structural similarity /// 0097178 // ruffle assembly // non-traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 213096_at T51252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T51252 /FEA=EST /DB_XREF=gi:653112 /DB_XREF=est:yb03f09.s1 /CLONE=IMAGE:70121 /UG=Hs.6360 KIAA0481 gene product T51252 transmembrane and coiled-coil domain family 2 TMCC2 9911 NM_001242925 /// NM_014858 /// XM_005245684 /// XM_005245685 /// XM_005245686 /// XM_005245689 /// XM_005245690 /// XM_006711694 0016192 // vesicle-mediated transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213097_s_at AI338837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI338837 /FEA=EST /DB_XREF=gi:4075764 /DB_XREF=est:qq28f09.x1 /CLONE=IMAGE:1933865 /UG=Hs.82254 zuotin related factor 1 AI338837 DnaJ (Hsp40) homolog, subfamily C, member 2 DNAJC2 27000 NM_001129887 /// NM_014377 /// XM_005250269 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051083 // 'de novo' cotranslational protein folding // traceable author statement /// 2000279 // negative regulation of DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213098_at AI567462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI567462 /FEA=EST /DB_XREF=gi:4525914 /DB_XREF=est:tn38e08.x1 /CLONE=IMAGE:2169926 /UG=Hs.94211 rcd1 (required for cell differentiation, S.pombe) homolog 1 /FL=gb:NM_005444.1 AI567462 RCD1 required for cell differentiation1 homolog (S. pombe) RQCD1 9125 NM_001271634 /// NM_001271635 /// NM_005444 /// NR_073390 /// XM_005246942 /// XM_005246943 /// XM_006712832 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 2000327 // positive regulation of ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213099_at AB018302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018302.1 /DEF=Homo sapiens mRNA for KIAA0759 protein, partial cds. /FEA=mRNA /GEN=KIAA0759 /PROD=KIAA0759 protein /DB_XREF=gi:3882238 /UG=Hs.7285 KIAA0759 protein AB018302 angel homolog 1 (Drosophila) ANGEL1 23357 NM_015305 /// XR_429300 /// XR_429301 /// XR_429302 213100_at AA127885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA127885 /FEA=EST /DB_XREF=gi:1687192 /DB_XREF=est:zl13b04.s1 /CLONE=IMAGE:501775 /UG=Hs.13350 Homo sapiens mRNA; cDNA DKFZp586D0918 (from clone DKFZp586D0918) AA127885 unc-5 homolog B (C. elegans) UNC5B 219699 NM_001244889 /// NM_170744 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0033564 // anterior/posterior axon guidance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213101_s_at Z78330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z78330 /FEA=EST /DB_XREF=gi:1495103 /DB_XREF=est:HSZ78330 /CLONE=2.49 (CEPH) /UG=Hs.10927 hypothetical protein EUROIMAGE1875335 Z78330 ARP3 actin-related protein 3 homolog (yeast) ACTR3 10096 NM_001277140 /// NM_005721 /// NR_102318 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043519 // regulation of myosin II filament organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 213102_at Z78330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z78330 /FEA=EST /DB_XREF=gi:1495103 /DB_XREF=est:HSZ78330 /CLONE=2.49 (CEPH) /UG=Hs.10927 hypothetical protein EUROIMAGE1875335 Z78330 ARP3 actin-related protein 3 homolog (yeast) ACTR3 10096 NM_001277140 /// NM_005721 /// NR_102318 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043519 // regulation of myosin II filament organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 213103_at AA128023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA128023 /FEA=EST /DB_XREF=gi:1687303 /DB_XREF=est:zl14d03.s1 /CLONE=IMAGE:501893 /UG=Hs.13649 Novel human gene mapping to chomosome 13, similar to rat RhoGAP AA128023 StAR-related lipid transfer (START) domain containing 13 STARD13 90627 NM_001243466 /// NM_001243474 /// NM_001243476 /// NM_052851 /// NM_178006 /// NM_178007 /// NM_178008 /// XM_005266586 /// XM_006719888 /// XM_006719889 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 213104_at AI799802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799802 /FEA=EST /DB_XREF=gi:5365274 /DB_XREF=est:wc43d09.x1 /CLONE=IMAGE:2321393 /UG=Hs.134846 Human DNA sequence from clone 316G12 on chromosome 16. Contains the gene for C2 domain protein KIAA0734, the gene for a novel protein similar to predicted yeast, worm and archae-bacterial proteins, a novel gene and the 3 part of the gene for a novel prot AI799802 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) TSR3 115939 NM_001001410 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 213105_s_at AI799802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799802 /FEA=EST /DB_XREF=gi:5365274 /DB_XREF=est:wc43d09.x1 /CLONE=IMAGE:2321393 /UG=Hs.134846 Human DNA sequence from clone 316G12 on chromosome 16. Contains the gene for C2 domain protein KIAA0734, the gene for a novel protein similar to predicted yeast, worm and archae-bacterial proteins, a novel gene and the 3 part of the gene for a novel prot AI799802 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) TSR3 115939 NM_001001410 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 213106_at AI769688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769688 /FEA=EST /DB_XREF=gi:5236197 /DB_XREF=est:wj25f11.x1 /CLONE=IMAGE:2403885 /UG=Hs.180737 Homo sapiens clone 23664 and 23905 mRNA sequence AI769688 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 ATP8A1 10396 NM_001105529 /// NM_006095 /// XM_005248043 /// XM_006713989 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0015917 // aminophospholipid transport // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015247 // aminophospholipid transporter activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213107_at R59093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R59093 /FEA=EST /DB_XREF=gi:829788 /DB_XREF=est:yh03e12.s1 /CLONE=IMAGE:41943 /UG=Hs.170204 KIAA0551 protein /FL=gb:AF172264.1 R59093 TRAF2 and NCK interacting kinase TNIK 23043 NM_001161560 /// NM_001161561 /// NM_001161562 /// NM_001161563 /// NM_001161564 /// NM_001161565 /// NM_001161566 /// NM_015028 /// NR_027767 /// XM_006713555 0006468 // protein phosphorylation // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007256 // activation of JNKK activity // inferred from direct assay /// 0007256 // activation of JNKK activity // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213108_at AW131813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW131813 /FEA=EST /DB_XREF=gi:6133420 /DB_XREF=est:xf34h12.x1 /CLONE=IMAGE:2620007 /UG=Hs.143535 calciumcalmodulin-dependent protein kinase (CaM kinase) II alpha /FL=gb:AF145710.1 gb:AF091486.1 AW131813 calcium/calmodulin-dependent protein kinase II alpha CAMK2A 815 NM_015981 /// NM_171825 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation 213109_at N25621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25621 /FEA=EST /DB_XREF=gi:1139969 /DB_XREF=est:yx78a01.s1 /CLONE=IMAGE:267816 /UG=Hs.170204 KIAA0551 protein /FL=gb:AF172264.1 N25621 TRAF2 and NCK interacting kinase TNIK 23043 NM_001161560 /// NM_001161561 /// NM_001161562 /// NM_001161563 /// NM_001161564 /// NM_001161565 /// NM_001161566 /// NM_015028 /// NR_027767 /// XM_006713555 0006468 // protein phosphorylation // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007256 // activation of JNKK activity // inferred from direct assay /// 0007256 // activation of JNKK activity // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213110_s_at AW052179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW052179 /FEA=EST /DB_XREF=gi:5914538 /DB_XREF=est:wx26h09.x1 /CLONE=IMAGE:2544833 /UG=Hs.169825 collagen, type IV, alpha 5 (Alport syndrome) /FL=gb:NM_000495.2 AW052179 collagen, type IV, alpha 5 COL4A5 1287 NM_000495 /// NM_033380 /// NM_033381 /// XM_005262070 /// XM_005262072 /// XM_006724616 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031594 // neuromuscular junction // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation 213111_at AB023198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023198.1 /DEF=Homo sapiens mRNA for KIAA0981 protein, partial cds. /FEA=mRNA /GEN=KIAA0981 /PROD=KIAA0981 protein /DB_XREF=gi:4589605 /UG=Hs.158135 KIAA0981 protein AB023198 phosphoinositide kinase, FYVE finger containing PIKFYVE 200576 NM_001002881 /// NM_001178000 /// NM_015040 /// NM_152671 /// XM_006712361 /// XM_006712362 /// XM_006712363 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000285 // 1-phosphatidylinositol-3-phosphate 5-kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0043813 // phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213112_s_at N30649 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N30649 /FEA=EST /DB_XREF=gi:1149169 /DB_XREF=est:yw77b03.s1 /CLONE=IMAGE:258221 /UG=Hs.279891 truncated calcium binding protein N30649 sequestosome 1 SQSTM1 8878 NM_001142298 /// NM_001142299 /// NM_003900 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006914 // autophagy // inferred from mutant phenotype /// 0006914 // autophagy // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0008104 // protein localization // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0016236 // macroautophagy // inferred from sequence or structural similarity /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from electronic annotation 213113_s_at AI630178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI630178 /FEA=EST /DB_XREF=gi:4681508 /DB_XREF=est:ad06a06.r1 /CLONE=ad06a06 (random) /UG=Hs.274453 hypothetical protein DKFZp762A227 AI630178 solute carrier family 43, member 3 SLC43A3 29015 NM_001278201 /// NM_001278206 /// NM_014096 /// NM_017611 /// NM_199329 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213114_at AI818736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI818736 /FEA=EST /DB_XREF=gi:5437815 /DB_XREF=est:wl11a08.x1 /CLONE=IMAGE:2424566 /UG=Hs.40500 similar to S. cerevisiae RER1 AI818736 213115_at AL031177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031177 /DEF=Human DNA sequence from clone 889N15 on chromosome Xq22.1-22.3. Contains part of the gene for a novel protein similar to X. laevis Cortical Thymocyte Marker CTX, the possibly alternatively spliced gene for 26S Proteasome subunit p28 (Ankyrin repea... /FEA=mRNA_3 /DB_XREF=gi:4071056 /UG=Hs.8763 Human DNA sequence from clone 889N15 on chromosome Xq22.1-22.3. Contains part of the gene for a novel protein similar to X. laevis Cortical Thymocyte Marker CTX, the possibly alternatively spliced gene for 26S Proteasome subunit p28 (Ankyrin repeat protei AL031177 autophagy related 4A, cysteine peptidase ATG4A 115201 NM_052936 /// NM_178270 /// NM_178271 /// XM_005262064 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006501 // C-terminal protein lipidation // not recorded /// 0006508 // proteolysis // inferred from direct assay /// 0006612 // protein targeting to membrane // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0051697 // protein delipidation // not recorded 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0004197 // cysteine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 213116_at AI191920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI191920 /FEA=EST /DB_XREF=gi:3743129 /DB_XREF=est:qd63a07.x1 /CLONE=IMAGE:1734132 /UG=Hs.2236 NIMA (never in mitosis gene a)-related kinase 3 AI191920 NIMA-related kinase 3 NEK3 4752 NM_001146099 /// NM_002498 /// NM_152720 /// NR_027415 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213117_at AW138594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138594 /FEA=EST /DB_XREF=gi:6142912 /DB_XREF=est:UI-H-BI1-acw-b-06-0-UI.s1 /CLONE=IMAGE:2715610 /UG=Hs.106283 hypothetical protein FLJ10262 AW138594 kelch-like family member 9 KLHL9 55958 NM_001040713 /// NM_018847 0000910 // cytokinesis // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0030496 // midbody // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 213118_at AL136821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136821.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M1526 (from clone DKFZp434M1526). /FEA=mRNA /GEN=DKFZp434M1526 /PROD=hypothetical protein /DB_XREF=gi:12053152 /UG=Hs.153293 KIAA0701 protein AL136821 UHRF1 binding protein 1-like UHRF1BP1L 23074 NM_001006947 /// NM_015054 /// XM_005268737 /// XM_005268738 /// XM_005268739 /// XM_005268740 /// XM_006719297 213119_at AW058600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW058600 /FEA=EST /DB_XREF=gi:5934239 /DB_XREF=est:wx23h08.x1 /CLONE=IMAGE:2544543 /UG=Hs.18593 Homo sapiens cDNA: FLJ21449 fis, clone COL04483, highly similar to AF010235 Homo sapiens mRNA from chromosome 5q31-33 region AW058600 solute carrier family 36 (proton/amino acid symporter), member 1 SLC36A1 206358 NM_078483 /// XM_005268386 /// XM_006714759 /// XM_006714760 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015804 // neutral amino acid transport // inferred from electronic annotation /// 0015808 // L-alanine transport // inferred from electronic annotation /// 0015816 // glycine transport // inferred from electronic annotation /// 0015824 // proline transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0035524 // proline transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from electronic annotation /// 0015187 // glycine transmembrane transporter activity // inferred from electronic annotation /// 0015193 // L-proline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 213120_at AA405798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA405798 /FEA=EST /DB_XREF=gi:2063781 /DB_XREF=est:zu57f04.s1 /CLONE=IMAGE:742111 /UG=Hs.153293 KIAA0701 protein AA405798 UHRF1 binding protein 1-like UHRF1BP1L 23074 NM_001006947 /// NM_015054 /// XM_005268737 /// XM_005268738 /// XM_005268739 /// XM_005268740 /// XM_006719297 213121_at W67744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W67744 /FEA=EST /DB_XREF=gi:1376836 /DB_XREF=est:zd39c08.s1 /CLONE=IMAGE:343022 /UG=Hs.174051 small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) W67744 small nuclear ribonucleoprotein 70kDa (U1) SNRNP70 6625 NM_001009820 /// NM_003089 /// XM_005259177 /// XM_005259178 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213122_at AI096375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI096375 /FEA=EST /DB_XREF=gi:3446286 /DB_XREF=est:qb91e08.x1 /CLONE=IMAGE:1707494 /UG=Hs.173094 Homo sapiens mRNA for KIAA1750 protein, partial cds AI096375 TSPY-like 5 TSPYL5 85453 NM_033512 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0071480 // cellular response to gamma radiation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213123_at BE222709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222709 /FEA=EST /DB_XREF=gi:8910027 /DB_XREF=est:hu51g06.x1 /CLONE=IMAGE:3173626 /UG=Hs.28785 microfibrillar-associated protein 3 BE222709 microfibrillar-associated protein 3 MFAP3 4238 NM_001135037 /// NM_001242336 /// NM_005927 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213124_at BG538800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG538800 /FEA=EST /DB_XREF=gi:13531033 /DB_XREF=est:602568243F1 /CLONE=IMAGE:4692850 /UG=Hs.59255 DKFZP434N043 protein BG538800 zinc finger protein 473 ZNF473 25888 NM_001006656 /// NM_015428 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006398 // histone mRNA 3'-end processing // inferred from direct assay /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0015030 // Cajal body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213125_at AW007573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007573 /FEA=EST /DB_XREF=gi:5856436 /DB_XREF=est:wt02e12.x1 /CLONE=IMAGE:2506318 /UG=Hs.43658 DKFZP586L151 protein AW007573 olfactomedin-like 2B OLFML2B 25903 NM_015441 /// XM_005245075 /// XM_005245076 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 213126_at BG230758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230758 /FEA=EST /DB_XREF=gi:12725810 /DB_XREF=est:naf39f08.x1 /CLONE=IMAGE:4143495 /UG=Hs.301756 ESTs, Weakly similar to T31475 hypothetical protein Y62F5A.1b - Caenorhabditis elegans C.elegans BG230758 mediator complex subunit 8 MED8 112950 NM_001001653 /// NM_052877 /// NM_201542 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213127_s_at BG230758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230758 /FEA=EST /DB_XREF=gi:12725810 /DB_XREF=est:naf39f08.x1 /CLONE=IMAGE:4143495 /UG=Hs.301756 ESTs, Weakly similar to T31475 hypothetical protein Y62F5A.1b - Caenorhabditis elegans C.elegans BG230758 mediator complex subunit 8 MED8 112950 NM_001001653 /// NM_052877 /// NM_201542 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213128_s_at AA527499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527499 /FEA=EST /DB_XREF=gi:2269568 /DB_XREF=est:ng41f07.s1 /CLONE=IMAGE:937381 /UG=Hs.301667 Homo sapiens mRNA; cDNA DKFZp566I043 (from clone DKFZp566I043) AA527499 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0035037 // sperm entry // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 213129_s_at AI970157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI970157 /FEA=EST /DB_XREF=gi:5766983 /DB_XREF=est:wq89h08.x1 /CLONE=IMAGE:2479263 /UG=Hs.77631 glycine cleavage system protein H (aminomethyl carrier) AI970157 glycine cleavage system protein H (aminomethyl carrier) /// glycine cleavage system H protein, mitochondrial-like GCSH /// LOC101060817 2653 /// 101060817 NM_004483 /// NR_033249 /// XM_003960892 0006546 // glycine catabolic process // traceable author statement /// 0019464 // glycine decarboxylation via glycine cleavage system // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032259 // methylation // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005960 // glycine cleavage complex // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 213130_at AB032967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032967.1 /DEF=Homo sapiens mRNA for KIAA1141 protein, partial cds. /FEA=mRNA /GEN=KIAA1141 /PROD=KIAA1141 protein /DB_XREF=gi:6329951 /UG=Hs.59255 DKFZP434N043 protein AB032967 zinc finger protein 473 ZNF473 25888 NM_001006656 /// NM_015428 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006398 // histone mRNA 3'-end processing // inferred from direct assay /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0015030 // Cajal body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213131_at R38389 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R38389 /FEA=EST /DB_XREF=gi:795845 /DB_XREF=est:yc96b12.s1 /CLONE=IMAGE:23744 /UG=Hs.74376 olfactomedin related ER localized protein R38389 olfactomedin 1 OLFM1 10439 NM_001282611 /// NM_001282612 /// NM_006334 /// NM_014279 /// NM_058199 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213132_s_at AL022237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022237 /DEF=Human DNA sequence from clone CTB-1191B2 on chromosome 22q13.2-13.3 Contains part of the BIK (NBK, BP4, BIP1) gene for BCL2-interacting killer (apoptosis-inducing), a 40S Ribososmal Protein S25 pseudogene and part of an alternatively spliced nove... /FEA=mRNA_4 /DB_XREF=gi:3845439 /UG=Hs.7436 putative acyltransferase AL022237 malonyl CoA:ACP acyltransferase (mitochondrial) MCAT 27349 NM_014507 /// NM_173467 /// NR_046423 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004314 // [acyl-carrier-protein] S-malonyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from direct assay /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213133_s_at AW237404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW237404 /FEA=EST /DB_XREF=gi:6569793 /DB_XREF=est:xm71d06.x1 /CLONE=IMAGE:2689643 /UG=Hs.77631 glycine cleavage system protein H (aminomethyl carrier) AW237404 glycine cleavage system protein H (aminomethyl carrier) /// glycine cleavage system H protein, mitochondrial-like GCSH /// LOC101060817 2653 /// 101060817 NM_004483 /// NR_033249 /// XM_003960892 0006546 // glycine catabolic process // traceable author statement /// 0019464 // glycine decarboxylation via glycine cleavage system // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032259 // methylation // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005960 // glycine cleavage complex // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 213134_x_at AI765445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI765445 /FEA=EST /DB_XREF=gi:5231954 /DB_XREF=est:wi80b08.x1 /CLONE=IMAGE:2399607 /UG=Hs.77311 BTG family, member 3 AI765445 BTG family, member 3 BTG3 10950 NM_001130914 /// NM_006806 /// XM_006723963 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213135_at U90902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U90902.1 /DEF=Human clone 23612 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1913880 /UG=Hs.82141 Human clone 23612 mRNA sequence U90902 T-cell lymphoma invasion and metastasis 1 TIAM1 7074 NM_003253 /// XM_005261037 /// XM_005261038 /// XM_005261039 /// XM_005261040 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0046875 // ephrin receptor binding // inferred from electronic annotation 213136_at AI828880 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI828880 /FEA=EST /DB_XREF=gi:5449551 /DB_XREF=est:wj37b02.x1 /CLONE=IMAGE:2404971 /UG=Hs.82829 protein tyrosine phosphatase, non-receptor type 2 AI828880 protein tyrosine phosphatase, non-receptor type 2 PTPN2 5771 NM_001207013 /// NM_002828 /// NM_080422 /// NM_080423 /// XM_005258124 /// XM_005258125 /// XM_005258126 /// XM_005258127 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0010888 // negative regulation of lipid storage // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from electronic annotation /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045650 // negative regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050922 // negative regulation of chemotaxis // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1902206 // negative regulation of interleukin-2-mediated signaling pathway // inferred from mutant phenotype /// 1902212 // negative regulation of prolactin signaling pathway // inferred from sequence or structural similarity /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from electronic annotation /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 1902227 // negative regulation of macrophage colony-stimulating factor signaling pathway // inferred from sequence or structural similarity /// 1902233 // negative regulation of positive thymic T cell selection // inferred from sequence or structural similarity /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 213137_s_at AI828880 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI828880 /FEA=EST /DB_XREF=gi:5449551 /DB_XREF=est:wj37b02.x1 /CLONE=IMAGE:2404971 /UG=Hs.82829 protein tyrosine phosphatase, non-receptor type 2 AI828880 protein tyrosine phosphatase, non-receptor type 2 PTPN2 5771 NM_001207013 /// NM_002828 /// NM_080422 /// NM_080423 /// XM_005258124 /// XM_005258125 /// XM_005258126 /// XM_005258127 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0010888 // negative regulation of lipid storage // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from electronic annotation /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045650 // negative regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050922 // negative regulation of chemotaxis // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1902206 // negative regulation of interleukin-2-mediated signaling pathway // inferred from mutant phenotype /// 1902212 // negative regulation of prolactin signaling pathway // inferred from sequence or structural similarity /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from electronic annotation /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 1902227 // negative regulation of macrophage colony-stimulating factor signaling pathway // inferred from sequence or structural similarity /// 1902233 // negative regulation of positive thymic T cell selection // inferred from sequence or structural similarity /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 213138_at M62324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M62324.1 /DEF=Human modulator recognition factor I (MRF-1) mRNA, 3 end. /FEA=mRNA /GEN=MRF-1 /PROD=modulator recognition factor I /DB_XREF=gi:188683 /UG=Hs.920 modulator recognition factor I M62324 AT rich interactive domain 5A (MRF1-like) ARID5A 10865 NM_006673 /// NM_212481 /// XM_005263856 /// XM_005263860 /// XM_005263861 /// XM_006712202 /// XM_006712203 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation 213139_at AI572079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI572079 /FEA=EST /DB_XREF=gi:4535453 /DB_XREF=est:tr73d01.x1 /CLONE=IMAGE:2223937 /UG=Hs.93005 slug (chicken homolog), zinc finger protein /FL=gb:NM_003068.1 AI572079 snail family zinc finger 2 SNAI2 6591 NM_003068 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001837 // epithelial to mesenchymal transition // inferred from mutant phenotype /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003273 // cell migration involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009314 // response to radiation // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010839 // negative regulation of keratinocyte proliferation // inferred from direct assay /// 0010957 // negative regulation of vitamin D biosynthetic process // inferred from direct assay /// 0014032 // neural crest cell development // inferred from mutant phenotype /// 0016477 // cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0032331 // negative regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0032642 // regulation of chemokine production // inferred from mutant phenotype /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred by curator /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0035414 // negative regulation of catenin import into nucleus // inferred from direct assay /// 0035921 // desmosome disassembly // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from mutant phenotype /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060429 // epithelium development // inferred from sequence or structural similarity /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070563 // negative regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900387 // negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000647 // negative regulation of stem cell proliferation // inferred from electronic annotation /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213140_s_at AB014593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014593.1 /DEF=Homo sapiens mRNA for KIAA0693 protein, partial cds. /FEA=mRNA /GEN=KIAA0693 /PROD=KIAA0693 protein /DB_XREF=gi:3327199 /UG=Hs.154429 KIAA0693 protein AB014593 synovial sarcoma translocation gene on chromosome 18-like 1 SS18L1 26039 NM_015558 /// NM_198935 /// XM_005260389 /// XM_005260391 /// XM_006723771 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213141_at AJ272212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ272212.1 /DEF=Homo sapiens mRNA for protein serine kinase (PSKH1 gene). /FEA=mRNA /GEN=PSKH1 /PROD=protein serine kinase /DB_XREF=gi:7981276 /UG=Hs.150601 chymotrypsin-like AJ272212 protein serine kinase H1 PSKH1 5681 NM_006742 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213142_x_at AV700415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700415 /FEA=EST /DB_XREF=gi:10302386 /DB_XREF=est:AV700415 /CLONE=GKCDGA04 /UG=Hs.12969 hypothetical protein AV700415 gamma-secretase activating protein GSAP 54103 NM_017439 /// XM_005250446 /// XM_005250448 /// XM_005250449 /// XM_005250450 /// XR_242248 0030162 // regulation of proteolysis // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from electronic annotation /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay 213143_at BE856707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856707 /FEA=EST /DB_XREF=gi:10370006 /DB_XREF=est:7f66f02.x1 /CLONE=IMAGE:3299643 /UG=Hs.12520 Homo sapiens clone 23568, 23621, 23795, 23873 and 23874 mRNA sequences BE856707 chromosome 2 open reading frame 72 C2orf72 257407 NM_001144994 0005515 // protein binding // inferred from electronic annotation 213144_at AI074611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI074611 /FEA=EST /DB_XREF=gi:3401255 /DB_XREF=est:oy99c09.x1 /CLONE=IMAGE:1673968 /UG=Hs.100651 golgi SNAP receptor complex member 2 AI074611 golgi SNAP receptor complex member 2 GOSR2 9570 NM_001012511 /// NM_004287 /// NM_054022 /// XM_005257843 /// XM_005257844 /// XM_005257845 /// XM_006722188 /// XM_006722189 /// XM_006722190 /// XM_006722191 /// XM_006722192 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement 213145_at BF001666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF001666 /FEA=EST /DB_XREF=gi:10701941 /DB_XREF=est:7g91d12.x1 /CLONE=IMAGE:3313847 /UG=Hs.12460 Homo sapiens clone 23870 mRNA sequence BF001666 F-box and leucine-rich repeat protein 14 FBXL14 144699 NM_152441 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213146_at AA521267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521267 /FEA=EST /DB_XREF=gi:2261810 /DB_XREF=est:aa75f03.s1 /CLONE=IMAGE:826781 /UG=Hs.103915 KIAA0346 protein AA521267 lysine (K)-specific demethylase 6B KDM6B 23135 NM_001080424 /// XM_005256549 /// XM_005256550 /// XM_005256551 /// XM_005256552 /// XM_005256554 /// XM_006721483 /// XM_006721484 0006954 // inflammatory response // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // not recorded 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // not recorded 213147_at AI375919 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375919 /FEA=EST /DB_XREF=gi:4175909 /DB_XREF=est:tc14d04.x1 /CLONE=IMAGE:2063815 /UG=Hs.110637 homeo box A10 /FL=gb:NM_018951.1 AI375919 homeobox A10 HOXA10 3206 NM_018951 /// NM_153715 /// NR_037939 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213148_at AW156899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW156899 /FEA=EST /DB_XREF=gi:6228300 /DB_XREF=est:au89c11.x1 /CLONE=IMAGE:2783444 /UG=Hs.12520 Homo sapiens clone 23568, 23621, 23795, 23873 and 23874 mRNA sequences AW156899 chromosome 2 open reading frame 72 C2orf72 257407 NM_001144994 0005515 // protein binding // inferred from electronic annotation 213149_at AW299740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299740 /FEA=EST /DB_XREF=gi:6709417 /DB_XREF=est:xs53f02.x1 /CLONE=IMAGE:2773371 /UG=Hs.115285 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) AW299740 dihydrolipoamide S-acetyltransferase DLAT 1737 NM_001931 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006085 // acetyl-CoA biosynthetic process // non-traceable author statement /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // non-traceable author statement /// 0045254 // pyruvate dehydrogenase complex // inferred from electronic annotation 0004742 // dihydrolipoyllysine-residue acetyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 213150_at BF792917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF792917 /FEA=EST /DB_XREF=gi:12097902 /DB_XREF=est:602253224F1 /CLONE=IMAGE:4345588 /UG=Hs.110637 homeo box A10 /FL=gb:NM_018951.1 BF792917 homeobox A10 HOXA10 3206 NM_018951 /// NM_153715 /// NR_037939 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213151_s_at AU157515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157515 /FEA=EST /DB_XREF=gi:11019036 /DB_XREF=est:AU157515 /CLONE=PLACE1008067 /UG=Hs.184326 CDC10 (cell division cycle 10, S. cerevisiae, homolog) AU157515 septin 7 SEPT7 989 NM_001011553 /// NM_001242956 /// NM_001788 /// XM_006715806 /// XM_006715807 /// XM_006715808 /// XM_006715809 /// XM_006715810 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016476 // regulation of embryonic cell shape // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 213152_s_at AI343248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI343248 /FEA=EST /DB_XREF=gi:4080454 /DB_XREF=est:tb94a05.x1 /CLONE=IMAGE:2061968 /UG=Hs.155160 Splicing factor, arginineserine-rich, 46kD AI343248 serine/arginine-rich splicing factor 8 SRSF8 10929 NM_032102 /// NR_103726 /// XR_428967 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213153_at AB028999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028999.1 /DEF=Homo sapiens mRNA for KIAA1076 protein, partial cds. /FEA=mRNA /GEN=KIAA1076 /PROD=KIAA1076 protein /DB_XREF=gi:5689488 /UG=Hs.154525 KIAA1076 protein AB028999 SET domain containing 1B SETD1B 23067 NM_015048 /// XM_005253858 /// XM_006719295 /// XM_006719296 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay 213154_s_at AI934125 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI934125 /FEA=EST /DB_XREF=gi:5672995 /DB_XREF=est:wn97c08.x1 /CLONE=IMAGE:2453774 /UG=Hs.17411 KIAA0699 protein AI934125 bicaudal D homolog 2 (Drosophila) BICD2 23299 NM_001003800 /// NM_015250 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0072385 // minus-end-directed organelle transport along microtubule // inferred from sequence or structural similarity /// 0072393 // microtubule anchoring at microtubule organizing center // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity 213155_at AB011095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011095.1 /DEF=Homo sapiens mRNA for KIAA0523 protein, partial cds. /FEA=mRNA /GEN=KIAA0523 /PROD=KIAA0523 protein /DB_XREF=gi:3043569 /UG=Hs.16032 KIAA0523 protein AB011095 uncharacterized LOC339166 /// WSC domain containing 1 LOC339166 /// WSCD1 23302 /// 339166 NM_015253 /// NR_040000 /// XM_005256572 /// XM_005256573 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation 213156_at BG251521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG251521 /FEA=EST /DB_XREF=gi:12761337 /DB_XREF=est:602363985F1 /CLONE=IMAGE:4472180 /UG=Hs.16193 Homo sapiens mRNA; cDNA DKFZp586B211 (from clone DKFZp586B211) BG251521 zinc finger and BTB domain containing 20 ZBTB20 26137 NM_001164342 /// NM_001164343 /// NM_001164344 /// NM_001164345 /// NM_001164346 /// NM_001164347 /// NM_015642 /// NR_121662 /// XM_005247339 /// XM_005247340 /// XM_005247341 /// XM_005247342 /// XM_005247343 /// XM_006713577 /// XM_006713578 /// XM_006713579 /// XM_006713580 /// XM_006713581 /// XM_006713833 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213157_s_at BF115148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF115148 /FEA=EST /DB_XREF=gi:10984624 /DB_XREF=est:hr84a04.x1 /CLONE=IMAGE:3135150 /UG=Hs.16032 KIAA0523 protein BF115148 uncharacterized LOC339166 /// WSC domain containing 1 LOC339166 /// WSCD1 23302 /// 339166 NM_015253 /// NR_040000 /// XM_005256572 /// XM_005256573 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation 213158_at AA045174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA045174 /FEA=EST /DB_XREF=gi:1523376 /DB_XREF=est:zk66a07.s1 /CLONE=IMAGE:487764 /UG=Hs.16193 Homo sapiens mRNA; cDNA DKFZp586B211 (from clone DKFZp586B211) AA045174 zinc finger and BTB domain containing 20 ZBTB20 26137 NM_001164342 /// NM_001164343 /// NM_001164344 /// NM_001164345 /// NM_001164346 /// NM_001164347 /// NM_015642 /// NR_121662 /// XM_005247339 /// XM_005247340 /// XM_005247341 /// XM_005247342 /// XM_005247343 /// XM_006713577 /// XM_006713578 /// XM_006713579 /// XM_006713580 /// XM_006713581 /// XM_006713833 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213159_at AB018348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018348.1 /DEF=Homo sapiens mRNA for KIAA0805 protein, partial cds. /FEA=mRNA /GEN=KIAA0805 /PROD=KIAA0805 protein /DB_XREF=gi:3882330 /UG=Hs.55947 KIAA0805 protein AB018348 pecanex homolog (Drosophila) PCNX 22990 NM_014982 /// XM_005267420 /// XM_005267421 /// XM_005267422 /// XM_005267423 /// XM_005267424 /// XM_005267425 /// XM_005267426 /// XM_005267427 /// XM_005267428 /// XM_005267429 /// XM_006720082 /// XR_245672 /// XR_245673 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213160_at D86964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D86964.1 /DEF=Human mRNA for KIAA0209 gene, partial cds. /FEA=mRNA /GEN=KIAA0209 /DB_XREF=gi:1504001 /UG=Hs.17211 dedicator of cyto-kinesis 2 D86964 dedicator of cytokinesis 2 DOCK2 1794 NM_004946 /// XM_005265830 0001766 // membrane raft polarization // inferred from electronic annotation /// 0001768 // establishment of T cell polarity // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0002277 // myeloid dendritic cell activation involved in immune response // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0046631 // alpha-beta T cell activation // inferred from electronic annotation /// 0046633 // alpha-beta T cell proliferation // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from direct assay 213161_at AI583393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI583393 /FEA=EST /DB_XREF=gi:4569290 /DB_XREF=est:ts09b07.x1 /CLONE=IMAGE:2228053 /UG=Hs.170453 tropomodulin AI583393 tropomodulin 1 /// thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 TMOD1 /// TSTD2 7111 /// 158427 NM_001166116 /// NM_003275 /// NM_139246 /// XM_005251740 /// XM_006716979 0006936 // muscle contraction // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 213162_at AI640861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI640861 /FEA=EST /DB_XREF=gi:4703970 /DB_XREF=est:wa27d03.x1 /CLONE=IMAGE:2299301 /UG=Hs.194625 dynein, cytoplasmic, light intermediate polypeptide 2 AI640861 dynein, cytoplasmic 1, light intermediate chain 2 DYNC1LI2 1783 NM_001286157 /// NM_006141 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051642 // centrosome localization // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005868 // cytoplasmic dynein complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 213164_at AI867198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI867198 /FEA=EST /DB_XREF=gi:5540214 /DB_XREF=est:wa01c11.x1 /CLONE=IMAGE:2296820 /UG=Hs.324787 solute carrier family 5 (inositol transporters), member 3 /FL=gb:NM_006933.1 AI867198 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 SLC5A3 6526 NM_006933 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0015798 // myo-inositol transport // traceable author statement /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015935 // small ribosomal subunit // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005367 // myo-inositol:sodium symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 213165_at AI041204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI041204 /FEA=EST /DB_XREF=gi:3280398 /DB_XREF=est:ov77g06.x1 /CLONE=IMAGE:1643386 /UG=Hs.323748 Homo sapiens clone CDABP0086 mRNA sequence AI041204 centrosomal protein 350kDa CEP350 9857 NM_014810 /// XM_005245638 /// XM_006711666 /// XM_006711667 /// XM_006711668 /// XM_006711669 /// XM_006711670 /// XM_006711671 0034453 // microtubule anchoring // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 213166_x_at BG332462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG332462 /FEA=EST /DB_XREF=gi:13138900 /DB_XREF=est:602432837F1 /CLONE=IMAGE:4550505 /UG=Hs.3343 phosphoglycerate dehydrogenase BG332462 microRNA 4784 /// mitotic spindle organizing protein 2A /// mitotic spindle organizing protein 2B MIR4784 /// MZT2A /// MZT2B 80097 /// 653784 /// 100616378 NM_001085365 /// NM_025029 /// NR_039945 /// XM_005263741 /// XM_005263742 /// XM_005263792 /// XM_005263795 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // inferred from direct assay /// 0008274 // gamma-tubulin ring complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 213167_s_at BF982927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF982927 /FEA=EST /DB_XREF=gi:12385739 /DB_XREF=est:602306318F1 /CLONE=IMAGE:4397525 /UG=Hs.324787 solute carrier family 5 (inositol transporters), member 3 /FL=gb:NM_006933.1 BF982927 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 SLC5A3 6526 NM_006933 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0015798 // myo-inositol transport // traceable author statement /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015935 // small ribosomal subunit // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005367 // myo-inositol:sodium symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 213168_at AU145005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145005 /FEA=EST /DB_XREF=gi:11006526 /DB_XREF=est:AU145005 /CLONE=HEMBA1003603 /UG=Hs.44450 Sp3 transcription factor AU145005 Sp3 transcription factor SP3 6670 NM_001017371 /// NM_001172712 /// NM_003111 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030219 // megakaryocyte differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0016605 // PML body // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213169_at BG109855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG109855 /FEA=EST /DB_XREF=gi:12603361 /DB_XREF=est:602279521F1 /CLONE=IMAGE:4367308 /UG=Hs.49476 Homo sapiens clone TUA8 Cri-du-chat region mRNA BG109855 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A SEMA5A 9037 NM_003966 /// XM_006714506 /// XM_006714507 /// XM_006714508 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0021536 // diencephalon development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from sequence or structural similarity /// 0035413 // positive regulation of catenin import into nucleus // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from sequence or structural similarity /// 1990256 // signal clustering // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from sequence or structural similarity /// 0035373 // chondroitin sulfate proteoglycan binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity /// 0045545 // syndecan binding // inferred from sequence or structural similarity 213170_at AA406605 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA406605 /FEA=EST /DB_XREF=gi:2064615 /DB_XREF=est:zv15b04.s1 /CLONE=IMAGE:753679 /UG=Hs.43728 hypothetical protein /FL=gb:NM_015696.1 AA406605 glutathione peroxidase 7 GPX7 2882 NM_015696 /// XM_006710586 /// XM_006710587 0006979 // response to oxidative stress // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0004601 // peroxidase activity // not recorded /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 213171_s_at AL121753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121753 /DEF=Human DNA sequence from clone RP4-614O4 on chromosome 20q11.1-12 Contains the 3 part of the MMP24 (matrix metalloproteinase 24 (membrane-inserted)) gene, the ITGB4BP (integrin beta 4 binding protein) gene, the 3 end of a novel gene, the 3 end o... /FEA=mRNA_4 /DB_XREF=gi:10944277 /UG=Hs.3743 matrix metalloproteinase 24 (membrane-inserted) AL121753 matrix metallopeptidase 24 (membrane-inserted) MMP24 10893 NM_006690 0006508 // proteolysis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213172_at AW235608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW235608 /FEA=EST /DB_XREF=gi:6567997 /DB_XREF=est:xn20d09.x1 /CLONE=IMAGE:2694257 /UG=Hs.79170 KIAA0227 protein AW235608 tetratricopeptide repeat domain 9 TTC9 23508 NM_015351 0005515 // protein binding // inferred from electronic annotation 213173_at AI815033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI815033 /FEA=EST /DB_XREF=gi:5426248 /DB_XREF=est:wk70c01.x1 /CLONE=IMAGE:2420736 /UG=Hs.55947 KIAA0805 protein AI815033 pecanex homolog (Drosophila) PCNX 22990 NM_014982 /// XM_005267420 /// XM_005267421 /// XM_005267422 /// XM_005267423 /// XM_005267424 /// XM_005267425 /// XM_005267426 /// XM_005267427 /// XM_005267428 /// XM_005267429 /// XM_006720082 /// XR_245672 /// XR_245673 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213174_at BE675549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675549 /FEA=EST /DB_XREF=gi:10036090 /DB_XREF=est:7f23c07.x1 /CLONE=IMAGE:3295500 /UG=Hs.79170 KIAA0227 protein BE675549 tetratricopeptide repeat domain 9 TTC9 23508 NM_015351 0005515 // protein binding // inferred from electronic annotation 213175_s_at AL049650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049650 /DEF=Human DNA sequence from clone 734P14 on chromosome 20. Contains a KRAB box and C2H2 Zinc finger domain protein pseudogene, the gene for snRNP (small nuclear ribonucleoprotein particle) proteins B and B and the gene for a novel transglutaminase si... /FEA=mRNA_3 /DB_XREF=gi:5123801 /UG=Hs.83753 small nuclear ribonucleoprotein polypeptides B and B1 AL049650 small nuclear ribonucleoprotein polypeptides B and B1 SNRPB 6628 NM_003091 /// NM_198216 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071208 // histone pre-mRNA DCP binding // inferred from electronic annotation 213176_s_at AI910869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI910869 /FEA=EST /DB_XREF=gi:5630605 /DB_XREF=est:wd20f04.x1 /CLONE=IMAGE:2328703 /UG=Hs.85087 latent transforming growth factor beta binding protein 4 AI910869 latent transforming growth factor beta binding protein 4 LTBP4 8425 NM_001042544 /// NM_001042545 /// NM_003573 0001558 // regulation of cell growth // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0016049 // cell growth // traceable author statement /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030162 // regulation of proteolysis // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030252 // growth hormone secretion // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0046879 // hormone secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // non-traceable author statement /// 0008083 // growth factor activity // non-traceable author statement /// 0008083 // growth factor activity // traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 213177_at AB028989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028989.1 /DEF=Homo sapiens mRNA for KIAA1066 protein, partial cds. /FEA=mRNA /GEN=KIAA1066 /PROD=KIAA1066 protein /DB_XREF=gi:5689468 /UG=Hs.88500 mitogen-activated protein kinase 8 interacting protein 3 AB028989 mitogen-activated protein kinase 8 interacting protein 3 MAPK8IP3 23162 NM_001040439 /// NM_015133 /// XM_005255187 /// XM_005255188 /// XM_005255190 /// XM_006720868 /// XM_006720869 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005078 // MAP-kinase scaffold activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 213178_s_at AB028989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028989.1 /DEF=Homo sapiens mRNA for KIAA1066 protein, partial cds. /FEA=mRNA /GEN=KIAA1066 /PROD=KIAA1066 protein /DB_XREF=gi:5689468 /UG=Hs.88500 mitogen-activated protein kinase 8 interacting protein 3 AB028989 mitogen-activated protein kinase 8 interacting protein 3 MAPK8IP3 23162 NM_001040439 /// NM_015133 /// XM_005255187 /// XM_005255188 /// XM_005255190 /// XM_006720868 /// XM_006720869 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005078 // MAP-kinase scaffold activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 213179_at BG289914 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289914 /FEA=EST /DB_XREF=gi:13046183 /DB_XREF=est:602381329F1 /CLONE=IMAGE:4499023 /UG=Hs.293687 ESTs BG289914 RCD1 required for cell differentiation1 homolog (S. pombe) RQCD1 9125 NM_001271634 /// NM_001271635 /// NM_005444 /// NR_073390 /// XM_005246942 /// XM_005246943 /// XM_006712832 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 2000327 // positive regulation of ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213180_s_at BE895285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE895285 /FEA=EST /DB_XREF=gi:10358525 /DB_XREF=est:601433529F1 /CLONE=IMAGE:3918799 /UG=Hs.100651 golgi SNAP receptor complex member 2 BE895285 golgi SNAP receptor complex member 2 GOSR2 9570 NM_001012511 /// NM_004287 /// NM_054022 /// XM_005257843 /// XM_005257844 /// XM_005257845 /// XM_006722188 /// XM_006722189 /// XM_006722190 /// XM_006722191 /// XM_006722192 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement 213181_s_at AL583528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583528 /FEA=EST /DB_XREF=gi:12952578 /DB_XREF=est:AL583528 /CLONE=CS0DD004YH21 (5 prime) /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog AL583528 molybdenum cofactor synthesis 1 MOCS1 4337 NM_001075098 /// NM_005942 /// NM_005943 /// NM_138928 /// NR_033233 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from direct assay /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from mutant phenotype /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019008 // molybdopterin synthase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation /// 0061597 // cyclic pyranopterin monophosphate synthase activity // inferred from electronic annotation /// 0061597 // cyclic pyranopterin monophosphate synthase activity // inferred from mutant phenotype 213182_x_at R78668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R78668 /FEA=EST /DB_XREF=gi:854949 /DB_XREF=est:yi74c04.r1 /CLONE=IMAGE:144966 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) R78668 cyclin-dependent kinase inhibitor 1C (p57, Kip2) CDKN1C 1028 NM_000076 /// NM_001122630 /// NM_001122631 /// XM_005252731 /// XM_005252732 /// XM_006725125 /// XM_006725126 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000080 // mitotic G1 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 213183_s_at N95363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N95363 /FEA=EST /DB_XREF=gi:1267635 /DB_XREF=est:zb71b11.s1 /CLONE=IMAGE:309021 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) N95363 213184_at N48361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N48361 /FEA=EST /DB_XREF=gi:1189527 /DB_XREF=est:yy79g10.s1 /CLONE=IMAGE:279810 /UG=Hs.15787 Homo sapiens mRNA; cDNA DKFZp564O1016 (from clone DKFZp564O1016) N48361 SUMO1/sentrin specific peptidase 5 SENP5 205564 NM_152699 /// XM_005269310 /// XM_005269311 /// XM_005269312 0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213185_at AI758896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI758896 /FEA=EST /DB_XREF=gi:5152621 /DB_XREF=est:ty94d10.x1 /CLONE=IMAGE:2286739 /UG=Hs.30512 KIAA0556 protein AI758896 KIAA0556 KIAA0556 23247 NM_015202 /// XM_005255201 /// XM_005255202 /// XM_005255203 /// XM_005255204 /// XM_005255206 /// XM_005255207 /// XM_005255208 /// XM_006721025 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 213186_at BG502305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG502305 /FEA=EST /DB_XREF=gi:13463822 /DB_XREF=est:602550583F1 /CLONE=IMAGE:4657940 /UG=Hs.165662 KIAA0675 gene product BG502305 DAZ interacting zinc finger protein 3 DZIP3 9666 NM_014648 /// XM_005247914 /// XM_005247915 /// XM_005247916 /// XM_005247917 /// XM_005247918 /// XM_005247919 0000209 // protein polyubiquitination // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213187_x_at BG538564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG538564 /FEA=EST /DB_XREF=gi:13530797 /DB_XREF=est:602567289F1 /CLONE=IMAGE:4691639 /UG=Hs.324746 alpha-2-HS-glycoprotein BG538564 ferritin, light polypeptide FTL 2512 NM_000146 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055072 // iron ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008043 // intracellular ferritin complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 213188_s_at AI823896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI823896 /FEA=EST /DB_XREF=gi:5444567 /DB_XREF=est:wj28e09.x1 /CLONE=IMAGE:2404168 /UG=Hs.23294 ESTs, Weakly similar to T15138 hypothetical protein T28F2.4 - Caenorhabditis elegans C.elegans AI823896 MYC induced nuclear antigen MINA 84864 NM_001042533 /// NM_001261829 /// NM_032778 /// NM_153182 /// XM_005247838 /// XR_241516 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 213189_at BE966695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966695 /FEA=EST /DB_XREF=gi:11772380 /DB_XREF=est:601661385R1 /CLONE=IMAGE:3916148 /UG=Hs.23294 ESTs, Weakly similar to T15138 hypothetical protein T28F2.4 - Caenorhabditis elegans C.elegans BE966695 MYC induced nuclear antigen MINA 84864 NM_001042533 /// NM_001261829 /// NM_032778 /// NM_153182 /// XM_005247838 /// XR_241516 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 213190_at R61519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R61519 /FEA=EST /DB_XREF=gi:832214 /DB_XREF=est:yh16c04.s1 /CLONE=IMAGE:37896 /UG=Hs.185807 Homo sapiens clone 24758 mRNA sequence R61519 component of oligomeric golgi complex 7 COG7 91949 NM_153603 /// XM_005255681 /// XR_429680 0006486 // protein glycosylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213191_at AF070530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070530.1 /DEF=Homo sapiens clone 24751 unknown mRNA. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3387885 /UG=Hs.29344 hypothetical protein, clone 24751 AF070530 toll-like receptor adaptor molecule 1 TICAM1 148022 NM_014261 /// NM_182919 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002281 // macrophage activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from mutant phenotype /// 0043496 // regulation of protein homodimerization activity // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0097342 // ripoptosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 213192_at AL031447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031447 /DEF=Human DNA sequence from clone 126A5 on chromosome 1p36.21-36.33. Contains three novel genes (one with DnaJ domains), the gene for KIAA0469 and the HKR3 gene for GLI-Kruppel family member HKR3. Contains ESTs, STSs, GSSs, three CpG islands, genomic ... /FEA=mRNA_1 /DB_XREF=gi:4826431 /UG=Hs.26938 Homo sapiens, clone IMAGE:4053044, mRNA, partial cds AL031447 THAP domain containing, apoptosis associated protein 3 THAP3 90326 NM_001195752 /// NM_001195753 /// NM_138350 /// XM_005263532 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213193_x_at AL559122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL559122 /FEA=EST /DB_XREF=gi:12904310 /DB_XREF=est:AL559122 /CLONE=CS0DJ014YE01 (5 prime) /UG=Hs.303157 T cell receptor beta locus AL559122 T cell receptor beta constant 1 TRBC1 28639 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0043382 // positive regulation of memory T cell differentiation // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from electronic annotation /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0045519 // interleukin-23 receptor binding // inferred from direct assay /// 0045519 // interleukin-23 receptor binding // inferred from electronic annotation 213194_at BF059159 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF059159 /FEA=EST /DB_XREF=gi:10813055 /DB_XREF=est:7k66g04.x1 /CLONE=IMAGE:3480391 /UG=Hs.301198 roundabout (axon guidance receptor, Drosophila) homolog 1 /FL=gb:AF040990.1 gb:NM_002941.1 BF059159 roundabout, axon guidance receptor, homolog 1 (Drosophila) ROBO1 6091 NM_001145845 /// NM_002941 /// NM_133631 /// XM_006713276 /// XM_006713277 /// XM_006713278 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0021836 // chemorepulsion involved in postnatal olfactory bulb interneuron migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from mutant phenotype /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0050772 // positive regulation of axonogenesis // inferred from direct assay /// 0050925 // negative regulation of negative chemotaxis // inferred from direct assay /// 0060763 // mammary duct terminal end bud growth // inferred from electronic annotation /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008046 // axon guidance receptor activity // traceable author statement /// 0030275 // LRR domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213195_at AI625844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI625844 /FEA=EST /DB_XREF=gi:4650775 /DB_XREF=est:ty65d07.x1 /CLONE=IMAGE:2283949 /UG=Hs.295963 ESTs AI625844 LYR motif containing 9 LYRM9 201229 NM_001076680 /// XM_005257943 /// XM_005257944 213196_at AI924293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924293 /FEA=EST /DB_XREF=gi:5660257 /DB_XREF=est:wn55a06.x1 /CLONE=IMAGE:2449330 /UG=Hs.301094 KIAA0326 protein AI924293 zinc finger protein 629 ZNF629 23361 NM_001080417 /// XM_005255222 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 213197_at AB006627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006627.1 /DEF=Homo sapiens mRNA for KIAA0289 gene, partial cds. /FEA=mRNA /GEN=KIAA0289 /DB_XREF=gi:2564325 /UG=Hs.6788 astrotactin AB006627 astrotactin 1 ASTN1 460 NM_001286164 /// NM_004319 /// NM_207108 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213198_at AL117643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117643.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M245 (from clone DKFZp434M245). /FEA=mRNA /DB_XREF=gi:5912233 /UG=Hs.5288 Homo sapiens mRNA; cDNA DKFZp434M245 (from clone DKFZp434M245) AL117643 activin A receptor, type IB ACVR1B 91 NM_004302 /// NM_020327 /// NM_020328 /// XM_006719685 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from genetic interaction /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046545 // development of primary female sexual characteristics // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // non-traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016361 // activin receptor activity, type I // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // non-traceable author statement /// 0034711 // inhibin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay 213199_at AL080220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080220.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586P0123 (from clone DKFZp586P0123); partial cds. /FEA=mRNA /GEN=DKFZp586P0123 /PROD=hypothetical protein /DB_XREF=gi:5262711 /UG=Hs.6285 DKFZP586P0123 protein AL080220 C2 calcium-dependent domain containing 3 C2CD3 26005 NM_001286577 /// NM_015531 /// XM_005273893 /// XM_005273895 /// XM_005273896 /// XM_005273897 /// XM_006718495 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021997 // neural plate axis specification // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030162 // regulation of proteolysis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035058 // nonmotile primary cilium assembly // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213200_at U93305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U93305 /DEF=Homo sapiens A4 differentiation-dependent protein (A4), triple LIM domain protein (LMO6), and synaptophysin (SYP) genes, complete cds; and calcium channel alpha-1 subunit (CACNA1F) gene, partial cds /FEA=mRNA_3 /DB_XREF=gi:2707598 /UG=Hs.75667 synaptophysin U93305 synaptophysin SYP 6855 NM_003179 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0016188 // synaptic vesicle maturation // non-traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // not recorded /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048499 // synaptic vesicle membrane organization // non-traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000474 // regulation of opioid receptor signaling pathway // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // non-traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 213201_s_at AJ011712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ011712 /DEF=Homo sapiens TNNT1 gene, exons 1-11 (and joined CDS) /FEA=mRNA_2 /DB_XREF=gi:4056561 /UG=Hs.73980 troponin T1, skeletal, slow AJ011712 troponin T type 1 (skeletal, slow) TNNT1 7138 NM_001126132 /// NM_001126133 /// NM_001291774 /// NM_003283 /// XM_006723343 /// XM_006723344 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0031444 // slow-twitch skeletal muscle fiber contraction // inferred from electronic annotation /// 0045932 // negative regulation of muscle contraction // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay /// 0005861 // troponin complex // inferred from mutant phenotype 0005523 // tropomyosin binding // inferred from mutant phenotype /// 0031014 // troponin T binding // inferred from electronic annotation 213202_at N30342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N30342 /FEA=EST /DB_XREF=gi:1148862 /DB_XREF=est:yw75g02.s1 /CLONE=IMAGE:258098 /UG=Hs.112078 KIAA0339 gene product N30342 SET domain containing 1A SETD1A 9739 NM_014712 /// XM_005255723 /// XM_006721106 /// XM_006721107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay 213203_at AI633709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633709 /FEA=EST /DB_XREF=gi:4685039 /DB_XREF=est:th71f03.x1 /CLONE=IMAGE:2124125 /UG=Hs.30174 small nuclear RNA activating complex, polypeptide 5, 19kD AI633709 small nuclear RNA activating complex, polypeptide 5, 19kDa SNAPC5 10302 NM_006049 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 213204_at AB014608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014608.1 /DEF=Homo sapiens mRNA for KIAA0708 protein, partial cds. /FEA=mRNA /GEN=KIAA0708 /PROD=KIAA0708 protein /DB_XREF=gi:3327229 /UG=Hs.117177 KIAA0708 protein AB014608 cullin 9 CUL9 23113 NM_015089 /// XM_006715029 /// XM_006715030 /// XM_006715031 /// XM_006715032 /// XR_427827 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213205_s_at AU159543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159543 /FEA=EST /DB_XREF=gi:11021064 /DB_XREF=est:AU159543 /CLONE=VESEN1000106 /UG=Hs.105399 KIAA0809 protein AU159543 RAD54-like 2 (S. cerevisiae) RAD54L2 23132 NM_015106 /// XM_006713061 /// XM_006713062 /// XR_427260 0008152 // metabolic process // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 213206_at AW149492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149492 /FEA=EST /DB_XREF=gi:6197388 /DB_XREF=est:xf38f08.x1 /CLONE=IMAGE:2620359 /UG=Hs.100651 golgi SNAP receptor complex member 2 AW149492 golgi SNAP receptor complex member 2 GOSR2 9570 NM_001012511 /// NM_004287 /// NM_054022 /// XM_005257843 /// XM_005257844 /// XM_005257845 /// XM_006722188 /// XM_006722189 /// XM_006722190 /// XM_006722191 /// XM_006722192 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement 213207_s_at AW149492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149492 /FEA=EST /DB_XREF=gi:6197388 /DB_XREF=est:xf38f08.x1 /CLONE=IMAGE:2620359 /UG=Hs.100651 golgi SNAP receptor complex member 2 AW149492 golgi SNAP receptor complex member 2 GOSR2 9570 NM_001012511 /// NM_004287 /// NM_054022 /// XM_005257843 /// XM_005257844 /// XM_005257845 /// XM_006722188 /// XM_006722189 /// XM_006722190 /// XM_006722191 /// XM_006722192 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement 213208_at AI801951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI801951 /FEA=EST /DB_XREF=gi:5367423 /DB_XREF=est:tx29a12.x1 /CLONE=IMAGE:2270974 /UG=Hs.196275 KIAA0240 protein AI801951 GLTSCR1-like GLTSCR1L 23506 NM_015349 /// XM_005248972 /// XM_005248973 213209_at BF058726 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF058726 /FEA=EST /DB_XREF=gi:10812622 /DB_XREF=est:7k34a08.x1 /CLONE=IMAGE:3477039 /UG=Hs.131846 PCAF associated factor 65 alpha /FL=gb:AF069735.1 gb:NM_006473.1 BF058726 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa TAF6L 10629 NM_006473 /// XM_005273714 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213210_at AI005317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI005317 /FEA=EST /DB_XREF=gi:3214827 /DB_XREF=est:ou13g10.x1 /CLONE=IMAGE:1626210 /UG=Hs.131846 PCAF associated factor 65 alpha /FL=gb:AF069735.1 gb:NM_006473.1 AI005317 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa TAF6L 10629 NM_006473 /// XM_005273714 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213211_s_at AI005317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI005317 /FEA=EST /DB_XREF=gi:3214827 /DB_XREF=est:ou13g10.x1 /CLONE=IMAGE:1626210 /UG=Hs.131846 PCAF associated factor 65 alpha /FL=gb:AF069735.1 gb:NM_006473.1 AI005317 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa TAF6L 10629 NM_006473 /// XM_005273714 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213212_x_at AI632181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI632181 /FEA=EST /DB_XREF=gi:4683511 /DB_XREF=est:ts85h05.x1 /CLONE=IMAGE:2238105 /UG=Hs.182982 golgin-67 AI632181 golgin A6 family-like 4 /// golgin A6 family-like 5, pseudogene /// golgin A6 family-like 9 /// putative golgin subfamily A member 6-like protein 4-like GOLGA6L4 /// GOLGA6L5P /// GOLGA6L9 /// LOC102724093 374650 /// 440295 /// 643707 /// 102724093 NM_001267536 /// NM_001282503 /// NM_001291420 /// NM_198079 /// NM_198181 /// NR_003246 /// XM_005254396 /// XM_006720531 /// XM_006720532 /// XM_006720533 /// XM_006720534 /// XM_006720535 /// XM_006720536 /// XM_006720537 /// XM_006720538 /// XM_006720634 /// XM_006726567 /// XR_429585 /// XR_433153 213213_at AL035669 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035669 /DEF=Human DNA sequence from clone RP5-885L7 on chromosome 20q13.2-13.33 Contains ESTs, STSs, GSSs and eight CpG islands. Contains the 3 end of the NTSR1 gene for high affinity neurotensin receptor 1, a putative novel gene, a novel gene similar to a f... /FEA=mRNA_3 /DB_XREF=gi:8979786 /UG=Hs.155313 death associated transcription factor 1 AL035669 death inducer-obliterator 1 DIDO1 11083 NM_001193369 /// NM_001193370 /// NM_022105 /// NM_033081 /// NM_080796 /// NM_080797 /// XM_006723684 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213214_x_at AW190090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190090 /FEA=EST /DB_XREF=gi:6464570 /DB_XREF=est:xl59a03.x1 /CLONE=IMAGE:2678956 /UG=Hs.14376 actin, gamma 1 AW190090 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 213215_at AI910895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI910895 /FEA=EST /DB_XREF=gi:5630631 /DB_XREF=est:wd20h09.x1 /CLONE=IMAGE:2328737 /UG=Hs.19720 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 42138 AI910895 adaptor-related protein complex 3, sigma 2 subunit /// C15orf38-AP3S2 readthrough AP3S2 /// C15orf38-AP3S2 10239 /// 100526783 NM_001199058 /// NM_005829 /// NR_023361 /// NR_037582 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 213216_at AL537463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL537463 /FEA=EST /DB_XREF=gi:12800956 /DB_XREF=est:AL537463 /CLONE=CS0DF025YP07 (3 prime) /UG=Hs.28169 KIAA0459 protein AL537463 OTU deubiquitinase 3 OTUD3 23252 NM_015207 /// XM_005245792 /// XM_005245793 /// XM_005245794 /// XM_006710481 0006508 // proteolysis // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0044313 // protein K6-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213217_at AU149572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149572 /FEA=EST /DB_XREF=gi:11011093 /DB_XREF=est:AU149572 /CLONE=NT2RM4002598 /UG=Hs.2352 adenylate cyclase 2 (brain) AU149572 adenylate cyclase 2 (brain) ADCY2 108 NM_020546 /// XR_427657 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from sequence or structural similarity /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005622 // intracellular // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008179 // adenylate cyclase binding // inferred from sequence or structural similarity /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 213218_at AV705032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705032 /FEA=EST /DB_XREF=gi:10722341 /DB_XREF=est:AV705032 /CLONE=ADBDRE06 /UG=Hs.237786 zinc finger protein 187 AV705032 zinc finger and SCAN domain containing 26 ZSCAN26 7741 NM_001023560 /// NM_001111039 /// NM_001287421 /// NM_001287422 /// NM_007151 /// NM_152736 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213219_at AB028983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028983.1 /DEF=Homo sapiens mRNA for KIAA1060 protein, partial cds. /FEA=mRNA /GEN=KIAA1060 /PROD=KIAA1060 protein /DB_XREF=gi:5689456 /UG=Hs.2352 adenylate cyclase 2 (brain) AB028983 adenylate cyclase 2 (brain) ADCY2 108 NM_020546 /// XR_427657 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from sequence or structural similarity /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005622 // intracellular // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008179 // adenylate cyclase binding // inferred from sequence or structural similarity /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 213220_at AV706096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV706096 /FEA=EST /DB_XREF=gi:10723384 /DB_XREF=est:AV706096 /CLONE=ADBAWH11 /UG=Hs.326248 Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 AV706096 BBSome interacting protein 1 BBIP1 92482 NM_001195304 /// NM_001195305 /// NM_001195306 /// NM_001195307 /// NM_001243783 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213221_s_at AB018324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018324.1 /DEF=Homo sapiens mRNA for KIAA0781 protein, partial cds. /FEA=mRNA /GEN=KIAA0781 /PROD=KIAA0781 protein /DB_XREF=gi:3882282 /UG=Hs.42676 KIAA0781 protein AB018324 salt-inducible kinase 2 SIK2 23235 NM_015191 0006468 // protein phosphorylation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046626 // regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213222_at AL049593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049593 /DEF=Human DNA sequence from clone RP4-654A7 on chromosome 20. Contains the gene for phospholipase C-beta-1 (KIAA0581, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1) (PLCB1, PLC-I), ESTs and GSSs /FEA=mRNA /DB_XREF=gi:10443476 /UG=Hs.41143 phosphoinositide-specific phospholipase C-beta 1 /FL=gb:NM_015192.1 AL049593 phospholipase C, beta 1 (phosphoinositide-specific) PLCB1 23236 NM_015192 /// NM_182734 /// XM_005260681 /// XM_006723555 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007215 // glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007613 // memory // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0035723 // interleukin-15-mediated signaling pathway // inferred from direct assay /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048639 // positive regulation of developmental growth // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060466 // activation of meiosis involved in egg activation // inferred from sequence or structural similarity /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0080154 // regulation of fertilization // inferred from sequence or structural similarity /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity /// 2000344 // positive regulation of acrosome reaction // inferred from sequence or structural similarity /// 2000438 // negative regulation of monocyte extravasation // inferred from sequence or structural similarity /// 2000560 // positive regulation of CD24 biosynthetic process // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from sequence or structural similarity /// 0004435 // phosphatidylinositol phospholipase C activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 213223_at AK025866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025866.1 /DEF=Homo sapiens cDNA: FLJ22213 fis, clone HRC01527. /FEA=mRNA /DB_XREF=gi:10438510 /UG=Hs.330570 Homo sapiens cDNA: FLJ22213 fis, clone HRC01527 AK025866 microRNA 6805 /// ribosomal protein L28 MIR6805 /// RPL28 6158 /// 102465483 NM_000991 /// NM_001136134 /// NM_001136135 /// NM_001136136 /// NM_001136137 /// NR_106863 /// XM_005259132 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213224_s_at AK025724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025724.1 /DEF=Homo sapiens cDNA: FLJ22071 fis, clone HEP11691. /FEA=mRNA /DB_XREF=gi:10438333 /UG=Hs.326248 Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 AK025724 BBSome interacting protein 1 BBIP1 92482 NM_001195304 /// NM_001195305 /// NM_001195306 /// NM_001195307 /// NM_001243783 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213225_at AJ271832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ271832.1 /DEF=Homo sapiens mRNA for protein phosphatase 1B2 (PPM1B2 gene). /FEA=mRNA /GEN=PPM1B2 /PROD=protein phosphatase 1B2 53 kDa isoform /DB_XREF=gi:12666516 /UG=Hs.5687 protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform /FL=gb:NM_002706.1 AJ271832 protein phosphatase, Mg2+/Mn2+ dependent, 1B PPM1B 5495 NM_001033556 /// NM_001033557 /// NM_002706 /// NM_177968 /// NM_177969 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213226_at AI346350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346350 /FEA=EST /DB_XREF=gi:4083556 /DB_XREF=est:qp50c06.x1 /CLONE=IMAGE:1926442 /UG=Hs.91728 polymyositisscleroderma autoantigen 1 (75kD) AI346350 cyclin A2 CCNA2 890 NM_001237 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 213227_at BE879873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE879873 /FEA=EST /DB_XREF=gi:10328649 /DB_XREF=est:601491389F1 /CLONE=IMAGE:3893302 /UG=Hs.9071 progesterone membrane binding protein BE879873 progesterone receptor membrane component 2 PGRMC2 10424 NM_006320 0043401 // steroid hormone mediated signaling pathway // traceable author statement 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003707 // steroid hormone receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 213228_at AK023913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023913.1 /DEF=Homo sapiens cDNA FLJ13851 fis, clone THYRO1000926, highly similar to Homo sapiens cAMP-specific phosphodiesterase 8B (PDE8B) mRNA. /FEA=mRNA /DB_XREF=gi:10435994 /UG=Hs.78106 phosphodiesterase 8B AK023913 phosphodiesterase 8B PDE8B 8622 NM_001029851 /// NM_001029852 /// NM_001029853 /// NM_001029854 /// NM_003719 /// XM_005248621 /// XM_005248623 /// XM_005248624 /// XM_006714725 /// XM_006714726 /// XM_006714727 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000156 // phosphorelay response regulator activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213229_at BF590131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF590131 /FEA=EST /DB_XREF=gi:11682455 /DB_XREF=est:nab19e04.x1 /CLONE=IMAGE:3266383 /UG=Hs.87889 helicase-moi BF590131 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213230_at AI422335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI422335 /FEA=EST /DB_XREF=gi:4268266 /DB_XREF=est:tf65f01.x1 /CLONE=IMAGE:2104153 /UG=Hs.78358 paraneoplastic antigen AI422335 cerebellar degeneration-related protein 2-like CDR2L 30850 NM_014603 /// XM_006721852 213231_at L19267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L19267.1 /DEF=Homo sapiens 59 protein mRNA, 3 end. /FEA=mRNA /DB_XREF=gi:306711 /UG=Hs.275924 dystrophia myotonica-containing WD repeat motif L19267 dystrophia myotonica, WD repeat containing DMWD 1762 NM_004943 0007126 // meiotic nuclear division // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 213232_at AB040900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040900.1 /DEF=Homo sapiens mRNA for KIAA1467 protein, partial cds. /FEA=mRNA /GEN=KIAA1467 /PROD=KIAA1467 protein /DB_XREF=gi:7959194 /UG=Hs.6189 KIAA1467 protein AB040900 KIAA1467 KIAA1467 57613 NM_020853 /// XM_005253450 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213233_s_at AA460694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA460694 /FEA=EST /DB_XREF=gi:2185814 /DB_XREF=est:zx69c04.s1 /CLONE=IMAGE:796710 /UG=Hs.106283 hypothetical protein FLJ10262 AA460694 kelch-like family member 9 KLHL9 55958 NM_001040713 /// NM_018847 0000910 // cytokinesis // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0030496 // midbody // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 213234_at AB040900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040900.1 /DEF=Homo sapiens mRNA for KIAA1467 protein, partial cds. /FEA=mRNA /GEN=KIAA1467 /PROD=KIAA1467 protein /DB_XREF=gi:7959194 /UG=Hs.6189 KIAA1467 protein AB040900 KIAA1467 KIAA1467 57613 NM_020853 /// XM_005253450 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213235_at BE504197 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE504197 /FEA=EST /DB_XREF=gi:9706605 /DB_XREF=est:hv86e11.x1 /CLONE=IMAGE:3180332 /UG=Hs.129061 Human Chromosome 16 BAC clone CIT987SK-A-101F10 BE504197 lysine-rich nucleolar protein 1 KNOP1 400506 NM_001012991 /// XM_005255316 /// XM_005255317 /// XM_006721046 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 213236_at AK025495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025495.1 /DEF=Homo sapiens cDNA: FLJ21842 fis, clone HEP01849. /FEA=mRNA /DB_XREF=gi:10438030 /UG=Hs.12002 KIAA0790 protein AK025495 SAM and SH3 domain containing 1 SASH1 23328 NM_015278 /// XM_005266874 /// XM_005266875 /// XM_006715406 0000209 // protein polyubiquitination // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 1900044 // regulation of protein K63-linked ubiquitination // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from mutant phenotype /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from mutant phenotype /// 1902498 // regulation of protein autoubiquitination // inferred from direct assay 0043234 // protein complex // inferred from mutant phenotype 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from direct assay 213237_at AI652058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652058 /FEA=EST /DB_XREF=gi:4736037 /DB_XREF=est:wb27d11.x1 /CLONE=IMAGE:2306901 /UG=Hs.129061 Human Chromosome 16 BAC clone CIT987SK-A-101F10 AI652058 lysine-rich nucleolar protein 1 KNOP1 400506 NM_001012991 /// XM_005255316 /// XM_005255317 /// XM_006721046 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 213238_at AI478147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478147 /FEA=EST /DB_XREF=gi:4371373 /DB_XREF=est:tm34f06.x1 /CLONE=IMAGE:2160035 /UG=Hs.173540 ATPase, Class V, type 10D AI478147 ATPase, class V, type 10D ATP10D 57205 NM_020453 /// XM_005248118 /// XM_005248119 /// XM_005248120 /// XM_006714024 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0004012 // phospholipid-translocating ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213239_at NM_006346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006346.1 /DEF=Homo sapiens PIBF1 gene product (PIBF1), mRNA. /FEA=CDS /GEN=PIBF1 /PROD=PIBF1 gene product /DB_XREF=gi:5453889 /UG=Hs.43913 PIBF1 gene product /FL=gb:NM_006346.1 NM_006346 progesterone immunomodulatory binding factor 1 PIBF1 10464 NM_006346 /// XM_005266229 /// XM_006719755 /// XM_006719756 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213240_s_at X07695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07695.1 /DEF=Human mRNA for cytokeratin 4 C-terminal region. /FEA=mRNA /PROD=cytokeratin 4 (408 AA) /DB_XREF=gi:34072 /UG=Hs.3235 keratin 4 X07695 keratin 4 KRT4 3851 NM_002272 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005882 // intermediate filament // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213241_at AF035307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035307.1 /DEF=Homo sapiens clone 23785 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661068 /UG=Hs.184697 Homo sapiens clone 23785 mRNA sequence AF035307 plexin C1 PLXNC1 10154 NM_005761 /// NR_037687 /// XM_006719186 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213242_x_at AB006622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006622.2 /DEF=Homo sapiens mRNA for KIAA0284 protein, partial cds. /FEA=mRNA /GEN=KIAA0284 /PROD=KIAA0284 protein /DB_XREF=gi:6635124 /UG=Hs.182536 KIAA0284 protein AB006622 centrosomal protein 170B CEP170B 283638 NM_001112726 /// NM_015005 /// XM_005267550 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213243_at AI052003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI052003 /FEA=EST /DB_XREF=gi:3307994 /DB_XREF=est:oy29c11.x1 /CLONE=IMAGE:1667252 /UG=Hs.21077 KIAA0532 protein AI052003 vacuolar protein sorting 13 homolog B (yeast) VPS13B 157680 NM_015243 /// NM_017890 /// NM_152564 /// NM_181661 /// NM_184042 /// NR_047582 /// XM_005250800 /// XM_005250801 /// XM_006716510 /// XM_006716511 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 213244_at AI207792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI207792 /FEA=EST /DB_XREF=gi:3769734 /DB_XREF=est:ao89d03.x1 /CLONE=IMAGE:1953029 /UG=Hs.306019 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI207792 secretory carrier membrane protein 4 SCAMP4 113178 NM_079834 0006810 // transport // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213245_at AL120173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL120173 /FEA=EST /DB_XREF=gi:5926072 /DB_XREF=est:DKFZp761C117_s1 /CLONE=DKFZp761C117 /UG=Hs.301663 ESTs AL120173 adenylate cyclase 1 (brain) ADCY1 107 NM_001281768 /// NM_021116 /// XM_005249584 /// XM_005249585 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213246_at AI346504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346504 /FEA=EST /DB_XREF=gi:4083710 /DB_XREF=est:qp51b12.x1 /CLONE=IMAGE:1926527 /UG=Hs.275352 DKFZP564F1123 protein AI346504 transmembrane protein 251 TMEM251 26175 NM_001098621 /// NM_015676 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213247_at AA716107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA716107 /FEA=EST /DB_XREF=gi:2728381 /DB_XREF=est:zg63d06.s1 /CLONE=IMAGE:398027 /UG=Hs.8963 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 248114 AA716107 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 SVEP1 79987 NM_153366 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213248_at AL577024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL577024 /FEA=EST /DB_XREF=gi:12939748 /DB_XREF=est:AL577024 /CLONE=CS0DI082YN19 (3 prime) /UG=Hs.7921 Homo sapiens mRNA; cDNA DKFZp566E183 (from clone DKFZp566E183) AL577024 uncharacterized LOC730101 LOC730101 730101 NR_024403 /// NR_024405 213249_at AU145127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145127 /FEA=EST /DB_XREF=gi:11006648 /DB_XREF=est:AU145127 /CLONE=HEMBA1003978 /UG=Hs.76798 f-box and leucine-rich repeat protein 7 /FL=gb:AF199356.1 gb:NM_012304.1 AU145127 F-box and leucine-rich repeat protein 7 FBXL7 23194 NM_001278317 /// NM_012304 /// XM_005248273 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 213250_at BE966372 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966372 /FEA=EST /DB_XREF=gi:11771715 /DB_XREF=est:601660420R1 /CLONE=IMAGE:3906101 /UG=Hs.66713 hepatitis delta antigen-interacting protein A BE966372 coiled-coil domain containing 85B CCDC85B 11007 NM_006848 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213251_at AV712064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV712064 /FEA=EST /DB_XREF=gi:10731370 /DB_XREF=est:AV712064 /CLONE=DCAAUD05 /UG=Hs.9456 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 AV712064 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 SMARCA5 8467 NM_003601 0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005677 // chromatin silencing complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0031010 // ISWI-type complex // inferred from electronic annotation /// 0031213 // RSF complex // inferred from physical interaction /// 0043596 // nuclear replication fork // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay 213252_at AI739005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI739005 /FEA=EST /DB_XREF=gi:5100986 /DB_XREF=est:wi34b03.x1 /CLONE=IMAGE:2392109 /UG=Hs.173448 KIAA0418 gene product AI739005 SH3 and PX domains 2A SH3PXD2A 9644 NM_014631 /// XM_005270294 /// XM_005270295 /// XM_005270297 /// XM_005270298 /// XM_006718079 /// XM_006718080 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation 0002102 // podosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 213253_at AU154486 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154486 /FEA=EST /DB_XREF=gi:11016007 /DB_XREF=est:AU154486 /CLONE=NT2RP4001238 /UG=Hs.119023 SMC2 (structural maintenance of chromosomes 2, yeast)-like 1 AU154486 structural maintenance of chromosomes 2 SMC2 10592 NM_001042550 /// NM_001042551 /// NM_001265602 /// NM_006444 /// XM_006716933 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 213254_at N64803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64803 /FEA=EST /DB_XREF=gi:1212632 /DB_XREF=est:yz31b07.s1 /CLONE=IMAGE:284629 /UG=Hs.117333 KIAA1093 protein N64803 trinucleotide repeat containing 6B TNRC6B 23112 NM_001024843 /// NM_001162501 /// NM_015088 0006417 // regulation of translation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031047 // gene silencing by RNA // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213256_at AW593996 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW593996 /FEA=EST /DB_XREF=gi:7281254 /DB_XREF=est:hg41g06.x1 /CLONE=IMAGE:2948218 /UG=Hs.124969 Homo sapiens clone 24707 mRNA sequence AW593996 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase MARCH3 115123 NM_178450 /// XM_005271870 0006897 // endocytosis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213257_at AJ290445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ290445.1 /DEF=Homo sapiens mRNA for KIAA0524SARM protein. /FEA=mRNA /GEN=KIAA0524SARM /PROD=KIAA0524SARM protein /DB_XREF=gi:7711001 /UG=Hs.128759 KIAA0524 protein AJ290445 sterile alpha and TIR motif containing 1 SARM1 23098 NM_015077 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 1901214 // regulation of neuron death // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 213258_at BF511231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511231 /FEA=EST /DB_XREF=gi:11594529 /DB_XREF=est:UI-H-BI4-aoi-g-11-0-UI.s1 /CLONE=IMAGE:3085244 /UG=Hs.288582 ESTs, Weakly similar to ubiquitous TPR motif, Y isoform H.sapiens BF511231 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 7035 NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 213259_s_at AI937297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI937297 /FEA=EST /DB_XREF=gi:5676167 /DB_XREF=est:wp75e06.x1 /CLONE=IMAGE:2467618 /UG=Hs.128759 KIAA0524 protein AI937297 sterile alpha and TIR motif containing 1 SARM1 23098 NM_015077 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 1901214 // regulation of neuron death // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 213260_at AU145890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145890 /FEA=EST /DB_XREF=gi:11007411 /DB_XREF=est:AU145890 /CLONE=HEMBA1006158 /UG=Hs.284186 forkhead box C1 /FL=gb:NM_001453.1 AU145890 forkhead box C1 FOXC1 2296 NM_001453 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001654 // eye development // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // not recorded /// 0007389 // pattern specification process // not recorded /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from direct assay /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // inferred from electronic annotation /// 0032808 // lacrimal gland development // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046620 // regulation of organ growth // not recorded /// 0048010 // vascular endothelial growth factor receptor signaling pathway // not recorded /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 1902257 // negative regulation of apoptotic process involved in outflow tract morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031490 // chromatin DNA binding // not recorded /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 213261_at AA035414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA035414 /FEA=EST /DB_XREF=gi:1507071 /DB_XREF=est:zk25a09.s1 /CLONE=IMAGE:471544 /UG=Hs.16950 KIAA0342 gene product AA035414 tetratricopeptide repeat and ankyrin repeat containing 1 TRANK1 9881 NM_014831 /// XM_006713432 0008152 // metabolic process // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213262_at AI932370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI932370 /FEA=EST /DB_XREF=gi:5671107 /DB_XREF=est:wd27e11.x1 /CLONE=IMAGE:2329388 /UG=Hs.159492 spastic ataxia of Charlevoix-Saguenay (sacsin) /FL=gb:NM_014363.1 AI932370 sacsin molecular chaperone SACS 26278 NM_001278055 /// NM_014363 /// XM_005266338 0006457 // protein folding // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0090084 // negative regulation of inclusion body assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0030424 // axon // traceable author statement /// 0030425 // dendrite // traceable author statement /// 0070852 // cell body fiber // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from physical interaction 213263_s_at AW025150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW025150 /FEA=EST /DB_XREF=gi:5878680 /DB_XREF=est:wu94e06.x1 /CLONE=IMAGE:2527714 /UG=Hs.211601 mitogen-activated protein kinase kinase kinase 12 AW025150 poly(rC) binding protein 2 PCBP2 5094 NM_001098620 /// NM_001128911 /// NM_001128912 /// NM_001128913 /// NM_001128914 /// NM_005016 /// NM_031989 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213264_at AW025150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW025150 /FEA=EST /DB_XREF=gi:5878680 /DB_XREF=est:wu94e06.x1 /CLONE=IMAGE:2527714 /UG=Hs.211601 mitogen-activated protein kinase kinase kinase 12 AW025150 poly(rC) binding protein 2 PCBP2 5094 NM_001098620 /// NM_001128911 /// NM_001128912 /// NM_001128913 /// NM_001128914 /// NM_005016 /// NM_031989 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213265_at AI570199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI570199 /FEA=EST /DB_XREF=gi:4533573 /DB_XREF=est:to76b07.x1 /CLONE=IMAGE:2184181 /UG=Hs.182183 Homo sapiens mRNA for caldesmon, 3 UTR AI570199 pepsin A-3-like /// pepsinogen 3, group I (pepsinogen A) /// pepsinogen 4, group I (pepsinogen A) /// pepsinogen 5, group I (pepsinogen A) LOC101929842 /// PGA3 /// PGA4 /// PGA5 5222 /// 643834 /// 643847 /// 101929842 NM_001079807 /// NM_001079808 /// NM_014224 /// XM_005276404 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213266_at BF592982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF592982 /FEA=EST /DB_XREF=gi:11685306 /DB_XREF=est:7j97g10.x1 /CLONE=IMAGE:3442771 /UG=Hs.20621 gamma tubulin ring complex protein (76p gene) BF592982 tumor protein p53 binding protein 1 TP53BP1 7158 NM_001141979 /// NM_001141980 /// NM_005657 /// XM_005254634 /// XM_005254635 /// XM_006720666 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006461 // protein complex assembly // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007020 // microtubule nucleation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred by curator 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // non-traceable author statement /// 0015630 // microtubule cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from mutant phenotype /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042162 // telomeric DNA binding // inferred from electronic annotation 213267_at AL162056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162056.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761N1024 (from clone DKFZp761N1024); partial cds. /FEA=mRNA /GEN=DKFZp761N1024 /PROD=hypothetical protein /DB_XREF=gi:7328103 /UG=Hs.278398 KIAA1117 protein AL162056 dopey family member 1 DOPEY1 23033 NM_001199942 /// NM_015018 /// XM_006715393 /// XM_006715394 /// XM_006715395 /// XM_006715396 /// XM_006715397 /// XM_006715398 /// XM_006715399 /// XM_006715400 /// XM_006715401 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity 213268_at Z98884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98884 /DEF=Human DNA sequence from clone RP3-467L1 on chromosome 1p36.21-36.33. Contains the 3 part of gene KIAA0833, the VAMP3 gene for vesicle-associated membrane protein 3 (cellubrevin), the PER3 gene for period (Drosophila) homolog 3 and the gene for ur... /FEA=mRNA_3 /DB_XREF=gi:5304861 /UG=Hs.26319 KIAA0833 protein Z98884 calmodulin binding transcription activator 1 CAMTA1 23261 NM_001195563 /// NM_001242701 /// NM_015215 /// NR_038934 /// XM_006710482 /// XM_006710483 /// XM_006710484 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213269_at N21541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21541 /FEA=EST /DB_XREF=gi:1126711 /DB_XREF=est:yx59h05.s1 /CLONE=IMAGE:266073 /UG=Hs.25275 Kruppel-type zinc finger protein N21541 zinc finger protein 248 ZNF248 57209 NM_001267597 /// NM_001267605 /// NM_001267606 /// NM_001267607 /// NM_021045 /// XM_005252541 /// XM_006717484 /// XM_006717485 /// XM_006717486 /// XR_428638 /// XR_428639 /// XR_428640 /// XR_428641 /// XR_428642 /// XR_428643 /// XR_428644 /// XR_428645 /// XR_428646 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213270_at AW450911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450911 /FEA=EST /DB_XREF=gi:6991687 /DB_XREF=est:UI-H-BI3-all-e-02-0-UI.s1 /CLONE=IMAGE:2737227 /UG=Hs.23205 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) AW450911 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) MPP2 4355 NM_001278370 /// NM_001278371 /// NM_001278372 /// NM_001278373 /// NM_001278374 /// NM_001278375 /// NM_001278376 /// NM_001278381 /// NM_005374 /// XM_006721912 /// XM_006721913 /// XM_006721914 0007165 // signal transduction // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 213271_s_at AB029040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029040.1 /DEF=Homo sapiens mRNA for KIAA1117 protein, partial cds. /FEA=mRNA /GEN=KIAA1117 /PROD=KIAA1117 protein /DB_XREF=gi:5689570 /UG=Hs.278398 KIAA1117 protein AB029040 dopey family member 1 DOPEY1 23033 NM_001199942 /// NM_015018 /// XM_006715393 /// XM_006715394 /// XM_006715395 /// XM_006715396 /// XM_006715397 /// XM_006715398 /// XM_006715399 /// XM_006715400 /// XM_006715401 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation 213272_s_at AF070596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070596.1 /DEF=Homo sapiens clone 24796 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387973 /UG=Hs.27191 hypothetical protein from clone 24796 AF070596 transmembrane protein 159 TMEM159 57146 NM_020422 /// XM_005255438 /// XM_005255439 /// XM_005255440 /// XM_006721066 /// XM_006721067 /// XM_006721068 /// XM_006721069 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213273_at BF112171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF112171 /FEA=EST /DB_XREF=gi:10941861 /DB_XREF=est:7l48d06.x1 /CLONE=IMAGE:3524770 /UG=Hs.5028 DKFZP564O0423 protein BF112171 teneurin transmembrane protein 4 TENM4 26011 NM_001098816 /// XM_006718498 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032289 // central nervous system myelin formation // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060912 // cardiac cell fate specification // inferred from electronic annotation /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 213274_s_at AA020826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA020826 /FEA=EST /DB_XREF=gi:1484570 /DB_XREF=est:ze64b04.s1 /CLONE=IMAGE:363727 /UG=Hs.297939 cathepsin B AA020826 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 213275_x_at W47179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W47179 /FEA=EST /DB_XREF=gi:1332046 /DB_XREF=est:zc34d07.s1 /CLONE=IMAGE:324205 /UG=Hs.297939 cathepsin B W47179 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 213276_at T15766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T15766 /FEA=EST /DB_XREF=gi:517928 /DB_XREF=est:IB1859 /UG=Hs.321572 Homo sapiens clone 25048 mRNA sequence T15766 calcium/calmodulin-dependent protein kinase II beta CAMK2B 816 NM_001220 /// NM_001293170 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 /// XM_005249859 /// XM_005249861 /// XM_005249862 /// XM_005249864 /// XM_006715776 /// XM_006715777 /// XM_006715778 /// XM_006715779 /// XM_006715780 /// XM_006715781 /// XM_006715782 /// XM_006715783 /// XM_006715784 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0002030 // inhibitory G-protein coupled receptor phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032222 // regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051823 // regulation of synapse structural plasticity // traceable author statement /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060466 // activation of meiosis involved in egg activation // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // traceable author statement /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213277_at AI344045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI344045 /FEA=EST /DB_XREF=gi:4081251 /DB_XREF=est:tc01g10.x1 /CLONE=IMAGE:2062626 /UG=Hs.85155 butyrate response factor 1 (EGF-response factor 1) /FL=gb:NM_004926.1 AI344045 ZFP36 ring finger protein-like 1 ZFP36L1 677 NM_001244698 /// NM_001244701 /// NM_004926 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213278_at AW014788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW014788 /FEA=EST /DB_XREF=gi:5863545 /DB_XREF=est:UI-H-BI0-aae-h-10-0-UI.s1 /CLONE=IMAGE:2709354 /UG=Hs.48802 Homo sapiens clone 23632 mRNA sequence AW014788 myotubularin related protein 9 MTMR9 66036 NM_015458 /// XM_005272396 0016311 // dephosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 213279_at AL050217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050217.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I0523 (from clone DKFZp586I0523). /FEA=mRNA /DB_XREF=gi:4884458 /UG=Hs.308467 Homo sapiens mRNA; cDNA DKFZp586I0523 (from clone DKFZp586I0523) AL050217 dehydrogenase/reductase (SDR family) member 1 DHRS1 115817 NM_001136050 /// NM_138452 /// XR_245662 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 213280_at AK000478 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000478.1 /DEF=Homo sapiens cDNA FLJ20471 fis, clone KAT06974. /FEA=mRNA /DB_XREF=gi:7020593 /UG=Hs.301552 KIAA1039 protein AK000478 RAP1 GTPase activating protein 2 RAP1GAP2 23108 NM_001100398 /// NM_015085 /// XM_005256541 /// XM_005256542 /// XM_005256543 /// XM_006721477 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation 213281_at BE327172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE327172 /FEA=EST /DB_XREF=gi:9200948 /DB_XREF=est:hw08a05.x1 /CLONE=IMAGE:3182288 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog BE327172 jun proto-oncogene JUN 3725 NM_002228 0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 213282_at BE501952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE501952 /FEA=EST /DB_XREF=gi:9704360 /DB_XREF=est:hw37d02.x1 /CLONE=IMAGE:3185091 /UG=Hs.5181 proliferation-associated 2G4, 38kD BE501952 apolipoprotein O-like APOOL 139322 NM_198450 /// XM_005262080 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213283_s_at BG285616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG285616 /FEA=EST /DB_XREF=gi:13037752 /DB_XREF=est:602380622F1 /CLONE=IMAGE:4498325 /UG=Hs.79971 sal (Drosophila)-like 2 BG285616 spalt-like transcription factor 2 SALL2 6297 NM_001291446 /// NM_001291447 /// NM_005407 /// NR_111966 /// NR_111967 /// XM_005267983 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0021915 // neural tube development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0016581 // NuRD complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213284_at BG482928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG482928 /FEA=EST /DB_XREF=gi:13415207 /DB_XREF=est:602502936F1 /CLONE=IMAGE:4616481 /UG=Hs.85155 butyrate response factor 1 (EGF-response factor 1) /FL=gb:NM_004926.1 BG482928 ZFP36 ring finger protein-like 1 ZFP36L1 677 NM_001244698 /// NM_001244701 /// NM_004926 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213285_at AV691491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV691491 /FEA=EST /DB_XREF=gi:10293354 /DB_XREF=est:AV691491 /CLONE=GKCEEB10 /UG=Hs.85335 Homo sapiens mRNA; cDNA DKFZp564D1462 (from clone DKFZp564D1462) AV691491 transmembrane protein 30B TMEM30B 161291 NM_001017970 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0070863 // positive regulation of protein exit from endoplasmic reticulum // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213286_at BF445199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF445199 /FEA=EST /DB_XREF=gi:11510260 /DB_XREF=est:nad21h02.x1 /CLONE=IMAGE:3366363 /UG=Hs.87150 Human clone A9A2BR11 (CAC)n(GTG)n repeat-containing mRNA BF445199 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213287_s_at X14487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14487 /DEF=Human gene for acidic (type I) cytokeratin 10 /FEA=mRNA /DB_XREF=gi:28316 /UG=Hs.99936 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) X14487 keratin 10 KRT10 3858 NM_000421 /// XM_005257343 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0030280 // structural constituent of epidermis // non-traceable author statement 213288_at AI761250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761250 /FEA=EST /DB_XREF=gi:5176917 /DB_XREF=est:wi68f01.x1 /CLONE=IMAGE:2398489 /UG=Hs.90797 Homo sapiens clone 23620 mRNA sequence AI761250 membrane bound O-acyltransferase domain containing 2 MBOAT2 129642 NM_138799 /// XR_241247 /// XR_241248 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 213289_at BE221922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE221922 /FEA=EST /DB_XREF=gi:8909343 /DB_XREF=est:hu04g12.x1 /CLONE=IMAGE:3165670 /UG=Hs.5181 proliferation-associated 2G4, 38kD BE221922 apolipoprotein O-like APOOL 139322 NM_198450 /// XM_005262080 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213290_at AL531750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL531750 /FEA=EST /DB_XREF=gi:12795243 /DB_XREF=est:AL531750 /CLONE=CS0DM003YO13 (3 prime) /UG=Hs.159263 collagen, type VI, alpha 2 AL531750 collagen, type VI, alpha 2 COL6A2 1292 NM_001849 /// NM_058174 /// NM_058175 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement 213291_s_at AA160522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA160522 /FEA=EST /DB_XREF=gi:1735889 /DB_XREF=est:zq46b10.s1 /CLONE=IMAGE:632731 /UG=Hs.301667 Homo sapiens mRNA; cDNA DKFZp566I043 (from clone DKFZp566I043) AA160522 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0035037 // sperm entry // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 213292_s_at AA908770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA908770 /FEA=EST /DB_XREF=gi:3048175 /DB_XREF=est:ol06a11.s1 /CLONE=IMAGE:1522652 /UG=Hs.283881 KIAA0713 protein AA908770 sorting nexin 13 SNX13 23161 NM_015132 /// XM_005249672 /// XM_005249673 /// XM_005249674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 213293_s_at AA083478 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA083478 /FEA=EST /DB_XREF=gi:1625564 /DB_XREF=est:zn32e02.s1 /CLONE=IMAGE:549146 /UG=Hs.295978 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 746039 AA083478 tripartite motif containing 22 TRIM22 10346 NM_001199573 /// NM_006074 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006955 // immune response // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070206 // protein trimerization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213294_at AV755522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV755522 /FEA=EST /DB_XREF=gi:10913370 /DB_XREF=est:AV755522 /CLONE=BMFAWG03 /UG=Hs.306117 Homo sapiens clone FLC0675 PRO2870 mRNA, complete cds AV755522 eukaryotic translation initiation factor 2-alpha kinase 2 EIF2AK2 5610 NM_001135651 /// NM_001135652 /// NM_002759 0000186 // activation of MAPKK activity // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0030683 // evasion or tolerance by virus of host immune response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900225 // regulation of NLRP3 inflammasome complex assembly // inferred from sequence or structural similarity /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from sequence or structural similarity /// 1901532 // regulation of hematopoietic progenitor cell differentiation // inferred from sequence or structural similarity /// 1902033 // regulation of hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 1902036 // regulation of hematopoietic stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213295_at AA555096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA555096 /FEA=EST /DB_XREF=gi:2325635 /DB_XREF=est:nj40e01.s1 /CLONE=IMAGE:994968 /UG=Hs.26295 Homo sapiens mRNA; cDNA DKFZp586D1122 (from clone DKFZp586D1122) AA555096 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 213296_at BF339133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF339133 /FEA=EST /DB_XREF=gi:11285556 /DB_XREF=est:602038434F1 /CLONE=IMAGE:4186304 /UG=Hs.247220 peroxisome biogenesis factor 10 BF339133 retention in endoplasmic reticulum sorting receptor 1 RER1 11079 NM_007033 /// XM_005244713 /// XM_006710305 /// XM_006710306 /// XM_006710307 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 213297_at AW131783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW131783 /FEA=EST /DB_XREF=gi:6133390 /DB_XREF=est:xf34e09.x1 /CLONE=IMAGE:2619976 /UG=Hs.23990 nucleolar protein family A, member 2 (HACA small nucleolar RNPs) AW131783 required for meiotic nuclear division 5 homolog B (S. cerevisiae) RMND5B 64777 NM_001288794 /// NM_001288795 /// NM_022762 /// XM_005265969 /// XM_005265971 /// XM_005265972 0005515 // protein binding // inferred from electronic annotation 213298_at X12492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X12492.1 /DEF=Human mRNA for CAAT-box binding transcription factor CTF-1 (syn. CTFNFI or CTF or NF-I or NF-1). /FEA=mRNA /DB_XREF=gi:30265 /UG=Hs.184771 nuclear factor IC (CCAAT-binding transcription factor) X12492 nuclear factor I/C (CCAAT-binding transcription factor) NFIC 4782 NM_001245002 /// NM_001245004 /// NM_001245005 /// NM_005597 /// NM_205843 /// XM_005259563 /// XM_005259564 /// XM_006722759 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 213299_at AW027070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027070 /FEA=EST /DB_XREF=gi:5885826 /DB_XREF=est:wt71g02.x1 /CLONE=IMAGE:2512946 /UG=Hs.104640 HIV-1 inducer of short transcripts binding protein /FL=gb:AF097916.1 gb:NM_015898.1 AW027070 zinc finger and BTB domain containing 7A ZBTB7A 51341 NM_015898 /// XM_005259570 /// XM_005259571 /// XM_005259572 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213300_at AW168132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW168132 /FEA=EST /DB_XREF=gi:6399657 /DB_XREF=est:xg60c11.x1 /CLONE=IMAGE:2632724 /UG=Hs.105850 KIAA0404 protein AW168132 autophagy related 2A ATG2A 23130 NM_015104 /// XM_005273849 /// XM_005273850 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0044804 // nucleophagy // 0000407 // pre-autophagosomal structure // not recorded /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213301_x_at AL538264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL538264 /FEA=EST /DB_XREF=gi:12801757 /DB_XREF=est:AL538264 /CLONE=CS0DF027YG21 (3 prime) /UG=Hs.183858 transcriptional intermediary factor 1 AL538264 tripartite motif containing 24 TRIM24 8805 NM_003852 /// NM_015905 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 1901796 // regulation of signal transduction by p53 class mediator // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0034056 // estrogen response element binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 213302_at AL044326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044326 /FEA=EST /DB_XREF=gi:5432548 /DB_XREF=est:DKFZp434A142_s1 /CLONE=DKFZp434A142 /UG=Hs.105478 phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) AL044326 phosphoribosylformylglycinamidine synthase PFAS 5198 NM_012393 /// XM_006721546 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // non-traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004642 // phosphoribosylformylglycinamidine synthase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 213303_x_at AF097916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF097916.1 /DEF=Homo sapiens HIV-1 inducer of short transcripts binding protein (FBI1) mRNA, complete cds. /FEA=CDS /GEN=FBI1 /PROD=HIV-1 inducer of short transcripts bindingprotein /DB_XREF=gi:3860088 /UG=Hs.104640 HIV-1 inducer of short transcripts binding protein /FL=gb:AF097916.1 gb:NM_015898.1 AF097916 zinc finger and BTB domain containing 7A ZBTB7A 51341 NM_015898 /// XM_005259570 /// XM_005259571 /// XM_005259572 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213304_at AI823592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI823592 /FEA=EST /DB_XREF=gi:5444263 /DB_XREF=est:wi71a04.x1 /CLONE=IMAGE:2398734 /UG=Hs.111373 KIAA0423 protein AI823592 family with sequence similarity 179, member B FAM179B 23116 NM_015091 /// XM_005267451 /// XM_006720083 /// XR_245674 0005488 // binding // inferred from electronic annotation 213305_s_at L42375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L42375.1 /DEF=Homo sapiens protein phosphatase 2A B56-gamma1 (PP2A) mRNA, 3 end of cds. /FEA=mRNA /GEN=PP2A /PROD=protein phosphatase 2A B56-gamma1 /DB_XREF=gi:1000891 /UG=Hs.171734 protein phosphatase 2, regulatory subunit B (B56), gamma isoform L42375 protein phosphatase 2, regulatory subunit B', gamma PPP2R5C 5527 NM_001161725 /// NM_001161726 /// NM_002719 /// NM_178586 /// NM_178587 /// NM_178588 /// XM_005267819 /// XM_005267820 /// XM_005267822 /// XM_005267823 /// XM_005267824 /// XM_005267826 /// XM_005267827 0006508 // proteolysis // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // non-traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // non-traceable author statement 213306_at AA917899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA917899 /FEA=EST /DB_XREF=gi:3057789 /DB_XREF=est:ol76e05.s1 /CLONE=IMAGE:1535552 /UG=Hs.169378 multiple PDZ domain protein AA917899 multiple PDZ domain protein MPDZ 8777 NM_001261406 /// NM_001261407 /// NM_003829 /// XM_005251622 /// XM_005251623 /// XM_006716885 /// XM_006716886 /// XM_006716887 /// XM_006716888 /// XM_006716889 /// XM_006716890 /// XM_006716891 /// XM_006716892 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 213307_at AF131790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131790.1 /DEF=Homo sapiens clone 24903 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406618 /UG=Hs.12696 cortactin SH3 domain-binding protein AF131790 SH3 and multiple ankyrin repeat domains 2 SHANK2 22941 NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity 213308_at BF435773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF435773 /FEA=EST /DB_XREF=gi:11448088 /DB_XREF=est:nab41f03.x1 /CLONE=IMAGE:3268373 /UG=Hs.12696 cortactin SH3 domain-binding protein BF435773 SH3 and multiple ankyrin repeat domains 2 SHANK2 22941 NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity 213309_at AL117515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117515.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L0735 (from clone DKFZp434L0735); partial cds. /FEA=mRNA /GEN=DKFZp434L0735 /PROD=hypothetical protein /DB_XREF=gi:5912029 /UG=Hs.54886 phospholipase C, epsilon 2 AL117515 phospholipase C-like 2 PLCL2 23228 NM_001144382 /// NM_015184 /// XM_006713073 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from direct assay 213310_at AI613483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI613483 /FEA=EST /DB_XREF=gi:4622650 /DB_XREF=est:ty37e12.x1 /CLONE=IMAGE:2281294 /UG=Hs.324504 Homo sapiens mRNA; cDNA DKFZp586J0720 (from clone DKFZp586J0720) AI613483 argonaute RISC catalytic component 2 /// cancer susceptibility candidate 7 (non-protein coding) /// /// Homo sapiens cDNA FLJ38845 fis, clone MESAN2003709. AGO2 /// CASC7 /// CASC7 /// DQ574852 27161 /// 286109 NM_001164623 /// NM_012154 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006379 // mRNA cleavage // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from mutant phenotype /// 0035279 // mRNA cleavage involved in gene silencing by miRNA // inferred from direct assay /// 0035279 // mRNA cleavage involved in gene silencing by miRNA // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from sequence or structural similarity /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // not recorded /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0035068 // micro-ribonucleoprotein complex // inferred from direct assay 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035197 // siRNA binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070551 // endoribonuclease activity, cleaving siRNA-paired mRNA // inferred from direct assay 213311_s_at BF000251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF000251 /FEA=EST /DB_XREF=gi:10700526 /DB_XREF=est:7h24e02.x1 /CLONE=IMAGE:3316922 /UG=Hs.227835 KIAA1049 protein BF000251 transcription factor 25 (basic helix-loop-helix) TCF25 22980 NM_014972 /// XM_005256297 /// XM_005256298 /// XM_005256299 /// XM_005256300 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213312_at NM_020425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_020425.1 /DEF=Homo sapiens hypothetical protein DKFZp586E1923 (DKFZP586E1923), mRNA. /FEA=CDS /GEN=DKFZP586E1923 /PROD=hypothetical protein DKFZp586E1923 /DB_XREF=gi:10092684 /UG=Hs.70769 hypothetical protein DKFZp586E1923 /FL=gb:NM_020425.1 NM_020425 small integral membrane protein 8 SMIM8 57150 NM_001042493 /// NM_001287445 /// NM_020425 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213313_at AI922519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922519 /FEA=EST /DB_XREF=gi:5658483 /DB_XREF=est:wm89a07.x1 /CLONE=IMAGE:2443092 /UG=Hs.55099 rab6 GTPase activating protein (GAP and centrosome-associated) AI922519 RAB GTPase activating protein 1 RABGAP1 23637 NM_012197 /// XM_005251866 /// XM_005251868 /// XM_006717031 /// XM_006717032 0007049 // cell cycle // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // traceable author statement 213314_at NM_020425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_020425.1 /DEF=Homo sapiens hypothetical protein DKFZp586E1923 (DKFZP586E1923), mRNA. /FEA=CDS /GEN=DKFZP586E1923 /PROD=hypothetical protein DKFZp586E1923 /DB_XREF=gi:10092684 /UG=Hs.70769 hypothetical protein DKFZp586E1923 /FL=gb:NM_020425.1 NM_020425 small integral membrane protein 8 SMIM8 57150 NM_001042493 /// NM_001287445 /// NM_020425 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213315_x_at L43577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L43577 /FEA=EST /DB_XREF=gi:899066 /DB_XREF=est:L43577 /CLONE=EST500 /UG=Hs.82171 Homo sapiens (clone 115392) mRNA L43577 chromosome X open reading frame 40A CXorf40A 91966 NM_001171907 /// NM_001171908 /// NM_001171909 /// NM_178124 /// XM_005262348 /// XM_005262349 /// XM_005262350 /// XM_005278212 0005515 // protein binding // inferred from physical interaction 213316_at AL050154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050154.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L0120 (from clone DKFZp586L0120). /FEA=mRNA /DB_XREF=gi:4884366 /UG=Hs.98314 Homo sapiens mRNA; cDNA DKFZp586L0120 (from clone DKFZp586L0120) AL050154 KIAA1462 KIAA1462 57608 NM_020848 /// XM_005252549 0007155 // cell adhesion // inferred from electronic annotation 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 213317_at AL049313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049313.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B076 (from clone DKFZp564B076). /FEA=mRNA /DB_XREF=gi:4500086 /UG=Hs.21103 Homo sapiens mRNA; cDNA DKFZp564B076 (from clone DKFZp564B076) AL049313 chloride intracellular channel 5 CLIC5 53405 NM_001114086 /// NM_001256023 /// NM_016929 /// NR_045672 /// NR_045673 /// NR_045674 /// XM_006715114 /// XM_006715115 0002021 // response to dietary excess // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213318_s_at BG028844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG028844 /FEA=EST /DB_XREF=gi:12417939 /DB_XREF=est:602292337F1 /CLONE=IMAGE:4387280 /UG=Hs.274348 HLA-B associated transcript-3 BG028844 BCL2-associated athanogene 6 BAG6 7917 NM_001098534 /// NM_001199697 /// NM_001199698 /// NM_004639 /// NM_080702 /// NM_080703 /// XM_005249393 /// XM_005249396 /// XM_005272880 /// XM_005272883 /// XM_005275034 /// XM_005275037 /// XM_005275169 /// XM_005275172 /// XM_005275292 /// XM_005275295 /// XM_005275464 /// XM_005275468 /// XM_005275597 /// XM_005275601 /// XM_006715192 /// XM_006715193 /// XM_006715194 /// XM_006715195 /// XM_006715196 /// XM_006715197 /// XM_006715198 /// XM_006715199 /// XM_006715200 /// XM_006715201 /// XM_006715202 /// XM_006715203 /// XM_006725509 /// XM_006725510 /// XM_006725511 /// XM_006725512 /// XM_006725513 /// XM_006725514 /// XM_006725515 /// XM_006725516 /// XM_006725517 /// XM_006725518 /// XM_006725519 /// XM_006725520 /// XM_006725725 /// XM_006725726 /// XM_006725727 /// XM_006725728 /// XM_006725729 /// XM_006725730 /// XM_006725731 /// XM_006725732 /// XM_006725733 /// XM_006725734 /// XM_006725735 /// XM_006725736 /// XM_006725835 /// XM_006725836 /// XM_006725837 /// XM_006725838 /// XM_006725839 /// XM_006725840 /// XM_006725841 /// XM_006725842 /// XM_006725843 /// XM_006725844 /// XM_006725845 /// XM_006725846 /// XM_006725923 /// XM_006725924 /// XM_006725925 /// XM_006725926 /// XM_006725927 /// XM_006725928 /// XM_006725929 /// XM_006725930 /// XM_006725931 /// XM_006725932 /// XM_006725933 /// XM_006725934 /// XM_006726025 /// XM_006726026 /// XM_006726027 /// XM_006726028 /// XM_006726029 /// XM_006726030 /// XM_006726031 /// XM_006726032 /// XM_006726033 /// XM_006726034 /// XM_006726035 /// XM_006726036 /// XM_006726113 /// XM_006726114 /// XM_006726115 /// XM_006726116 /// XM_006726117 /// XM_006726118 /// XM_006726119 /// XM_006726120 /// XM_006726121 /// XM_006726122 /// XM_006726123 /// XM_006726124 0001822 // kidney development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from sequence or structural similarity /// 0043022 // ribosome binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from sequence or structural similarity 213319_s_at AW170359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW170359 /FEA=EST /DB_XREF=gi:6401884 /DB_XREF=est:xn60c12.x1 /CLONE=IMAGE:2698102 /UG=Hs.1139 cold shock domain protein A AW170359 Y box binding protein 3 YBX3 8531 NM_001145426 /// NM_003651 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred by curator /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from mutant phenotype /// 2000767 // positive regulation of cytoplasmic translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 213320_at AL551971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL551971 /FEA=EST /DB_XREF=gi:12890422 /DB_XREF=est:AL551971 /CLONE=CS0DI060YG02 (3 prime) /UG=Hs.152337 protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3 AL551971 protein arginine methyltransferase 3 PRMT3 10196 NM_001145166 /// NM_001145167 /// NM_005788 /// XM_005252730 /// XM_006718121 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018216 // peptidyl-arginine methylation // inferred from electronic annotation /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from direct assay /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0016274 // protein-arginine N-methyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from electronic annotation 213321_at AL531533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL531533 /FEA=EST /DB_XREF=gi:12795026 /DB_XREF=est:AL531533 /CLONE=CS0DM002YI17 (3 prime) /UG=Hs.1265 branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) AL531533 branched chain keto acid dehydrogenase E1, beta polypeptide BCKDHB 594 NM_000056 /// NM_183050 /// XM_005248756 /// XM_006715542 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // inferred from mutant phenotype /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from mutant phenotype /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from mutant phenotype 0003824 // catalytic activity // inferred from electronic annotation /// 0003826 // alpha-ketoacid dehydrogenase activity // inferred from electronic annotation /// 0003863 // 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation 213322_at AL031778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031778 /DEF=Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine... /FEA=mRNA_2 /DB_XREF=gi:4153958 /UG=Hs.183056 Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine recepto AL031778 O-acyl-ADP-ribose deacylase 1 OARD1 221443 NM_145063 0042278 // purine nucleoside metabolic process // inferred from direct assay 0001883 // purine nucleoside binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from direct assay 213323_s_at BE855831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE855831 /FEA=EST /DB_XREF=gi:10368259 /DB_XREF=est:7g09a05.x1 /CLONE=IMAGE:3305936 /UG=Hs.25347 KIAA1031 protein BE855831 zinc finger CCCH-type containing 7B ZC3H7B 23264 NM_017590 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213324_at AK024281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024281.1 /DEF=Homo sapiens cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA. /FEA=mRNA /DB_XREF=gi:10436622 /UG=Hs.198298 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog AK024281 SRC proto-oncogene, non-receptor tyrosine kinase SRC 6714 NM_005417 /// NM_198291 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0033146 // regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033625 // positive regulation of integrin activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043114 // regulation of vascular permeability // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045124 // regulation of bone resorption // traceable author statement /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048477 // oogenesis // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051895 // negative regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051902 // negative regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0060065 // uterus development // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071393 // cellular response to progesterone stimulus // inferred from sequence or structural similarity /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from physical interaction 213325_at AA129716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129716 /FEA=EST /DB_XREF=gi:1690145 /DB_XREF=est:zn91d05.s1 /CLONE=IMAGE:565545 /UG=Hs.21201 nectin 3; DKFZP566B0846 protein /FL=gb:NM_015480.1 gb:AF282874.1 AA129716 poliovirus receptor-related 3 PVRL3 25945 NM_001243286 /// NM_001243288 /// NM_015480 /// XM_005247321 /// XM_005247322 /// XR_427363 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0009566 // fertilization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 213326_at AU150319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150319 /FEA=EST /DB_XREF=gi:11011840 /DB_XREF=est:AU150319 /CLONE=NT2RP2002398 /UG=Hs.20021 vesicle-associated membrane protein 1 (synaptobrevin 1) AU150319 vesicle-associated membrane protein 1 (synaptobrevin 1) VAMP1 6843 NM_014231 /// NM_016830 /// NM_199245 /// XM_006719011 /// XM_006719012 /// XM_006719013 /// XM_006719014 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 213327_s_at AI820101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI820101 /FEA=EST /DB_XREF=gi:5439180 /DB_XREF=est:wg56d12.x1 /CLONE=IMAGE:2369111 /UG=Hs.42400 ubiquitin specific protease 12 AI820101 ubiquitin specific peptidase 12 USP12 219333 NM_182488 /// XM_005266282 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 213328_at AI936517 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI936517 /FEA=EST /DB_XREF=gi:5675387 /DB_XREF=est:wd28h08.x1 /CLONE=IMAGE:2329503 /UG=Hs.48332 NIMA (never in mitosis gene a)-related kinase 1 AI936517 NIMA-related kinase 1 NEK1 4750 NM_001199397 /// NM_001199398 /// NM_001199399 /// NM_001199400 /// NM_012224 /// XM_006714227 /// XM_006714228 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000242 // pericentriolar material // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213329_at AA742261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA742261 /FEA=EST /DB_XREF=gi:2784261 /DB_XREF=est:ny80d02.s1 /CLONE=IMAGE:1284579 /UG=Hs.5003 KIAA0456 protein AA742261 SLIT-ROBO Rho GTPase activating protein 2 /// SLIT-ROBO Rho GTPase activating protein 2B /// SLIT-ROBO Rho GTPase activating protein 2C SRGAP2 /// SRGAP2B /// SRGAP2C 23380 /// 647135 /// 653464 NM_001042758 /// NM_001170637 /// NM_001271870 /// NM_001271872 /// NM_015326 /// NR_034178 /// XM_005277419 /// XM_005277420 /// XM_005277421 /// XM_005277422 /// XM_005277497 /// XM_005277498 /// XM_005277499 /// XM_005277510 /// XM_005277511 /// XM_005277512 /// XM_005277513 /// XM_005277514 /// XM_005277515 /// XM_006711246 /// XM_006711247 0003363 // lamellipodium assembly involved in ameboidal cell migration // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0021816 // extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0021816 // extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0051014 // actin filament severing // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051490 // negative regulation of filopodium assembly // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0060996 // dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 2001223 // negative regulation of neuron migration // inferred from direct assay /// 2001224 // positive regulation of neuron migration // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044327 // dendritic spine head // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0045335 // phagocytic vesicle // inferred from sequence or structural similarity 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0030675 // Rac GTPase activator activity // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048365 // Rac GTPase binding // inferred from direct assay 213330_s_at BE886580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE886580 /FEA=EST /DB_XREF=gi:10341010 /DB_XREF=est:601509325F1 /CLONE=IMAGE:3910566 /UG=Hs.75612 stress-induced-phosphoprotein 1 (Hsp70Hsp90-organizing protein) BE886580 stress-induced phosphoprotein 1 STIP1 10963 NM_001282652 /// NM_001282653 /// NM_006819 0006950 // response to stress // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 213331_s_at AV700007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700007 /FEA=EST /DB_XREF=gi:10301978 /DB_XREF=est:AV700007 /CLONE=GKCBQC12 /UG=Hs.48332 NIMA (never in mitosis gene a)-related kinase 1 AV700007 NIMA-related kinase 1 NEK1 4750 NM_001199397 /// NM_001199398 /// NM_001199399 /// NM_001199400 /// NM_012224 /// XM_006714227 /// XM_006714228 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000242 // pericentriolar material // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213332_at AL031290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031290 /DEF=Human DNA sequence from clone 774I24 on chromosome 1q24.1-24.3 Contains protein similar to pregnancy-associated plasma protein A precursor neuronal migration protein astrotactin, ESTs, STS and GSS /FEA=mRNA_1 /DB_XREF=gi:3550114 /UG=Hs.9654 similar to pregnancy-associated plasma protein A precursor AL031290 pappalysin 2 PAPPA2 60676 NM_020318 /// NM_021936 /// XM_005245422 0001558 // regulation of cell growth // non-traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213333_at AL520774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL520774 /FEA=EST /DB_XREF=gi:12784267 /DB_XREF=est:AL520774 /CLONE=CS0DB002YH07 (3 prime) /UG=Hs.111076 malate dehydrogenase 2, NAD (mitochondrial) AL520774 malate dehydrogenase 2, NAD (mitochondrial) MDH2 4191 NM_001282403 /// NM_001282404 /// NM_005918 /// NR_104165 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from direct assay /// 0006108 // malate metabolic process // inferred from mutant phenotype /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030060 // L-malate dehydrogenase activity // not recorded /// 0030060 // L-malate dehydrogenase activity // inferred from direct assay /// 0030060 // L-malate dehydrogenase activity // inferred from mutant phenotype /// 0043621 // protein self-association // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046554 // malate dehydrogenase (NADP+) activity // inferred from electronic annotation 213334_x_at BE676218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE676218 /FEA=EST /DB_XREF=gi:10036759 /DB_XREF=est:7f25d10.x1 /CLONE=IMAGE:3295699 /UG=Hs.6487 Xq28, 2000bp sequence contg. ORF BE676218 HAUS augmin-like complex, subunit 7 HAUS7 55559 NM_017518 /// NM_207106 /// NM_207107 /// NR_073156 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0070652 // HAUS complex // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008296 // 3'-5'-exodeoxyribonuclease activity // inferred from direct assay /// 0008296 // 3'-5'-exodeoxyribonuclease activity // traceable author statement /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213335_s_at AK001922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001922.1 /DEF=Homo sapiens cDNA FLJ11060 fis, clone PLACE1004751, highly similar to Homo sapiens mRNA for alpha2,3-sialyltransferase ST3Gal VI. /FEA=mRNA /DB_XREF=gi:7023485 /UG=Hs.34578 alpha2,3-sialyltransferase AK001922 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 ST3GAL6 10402 NM_001271142 /// NM_001271145 /// NM_001271146 /// NM_001271147 /// NM_001271148 /// NM_006100 /// XM_005247067 /// XM_005247068 /// XM_005247069 /// XM_005247070 /// XM_005247071 /// XM_005247072 /// XM_006713474 /// XM_006713475 /// XM_006713476 /// XR_427357 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052798 // beta-galactoside alpha-2,3-sialyltransferase activity // inferred from direct assay 213336_at AI826454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI826454 /FEA=EST /DB_XREF=gi:5447125 /DB_XREF=est:wk34d12.x1 /CLONE=IMAGE:2417303 /UG=Hs.194688 bromodomain adjacent to zinc finger domain, 1B AI826454 bromodomain adjacent to zinc finger domain, 1B BAZ1B 9031 NM_023005 /// NM_032408 /// XM_005250683 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034725 // DNA replication-dependent nucleosome disassembly // inferred from mutant phenotype /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay /// 0071884 // vitamin D receptor activator activity // inferred from electronic annotation 213337_s_at AA877218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA877218 /FEA=EST /DB_XREF=gi:2986295 /DB_XREF=est:ob15e08.s1 /CLONE=IMAGE:1323782 /UG=Hs.50640 JAK binding protein AA877218 suppressor of cytokine signaling 1 SOCS1 8651 NM_003745 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046426 // negative regulation of JAK-STAT cascade // non-traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction 213338_at BF062629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062629 /FEA=EST /DB_XREF=gi:10821539 /DB_XREF=est:7h62h07.x1 /CLONE=IMAGE:3320605 /UG=Hs.35861 DKFZP586E1621 protein BF062629 transmembrane protein 158 (gene/pseudogene) TMEM158 25907 NM_015444 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0042277 // peptide binding // inferred from electronic annotation 213339_at AB007964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007964.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0495. /FEA=mRNA /DB_XREF=gi:3413939 /UG=Hs.49658 KIAA0495 AB007964 TP73 antisense RNA 1 TP73-AS1 57212 NM_207306 /// NR_033708 /// NR_033709 /// NR_033710 /// NR_033711 /// NR_033712 0005576 // extracellular region // inferred from electronic annotation 213340_s_at AI073551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073551 /FEA=EST /DB_XREF=gi:3400195 /DB_XREF=est:ov45e10.x1 /CLONE=IMAGE:1640298 /UG=Hs.49658 KIAA0495 AI073551 TP73 antisense RNA 1 TP73-AS1 57212 NM_207306 /// NR_033708 /// NR_033709 /// NR_033710 /// NR_033711 /// NR_033712 0005576 // extracellular region // inferred from electronic annotation 213341_at AI862658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI862658 /FEA=EST /DB_XREF=gi:5526765 /DB_XREF=est:wj27d03.x1 /CLONE=IMAGE:2404037 /UG=Hs.47367 hypothetical protein from EUROIMAGE 783647 AI862658 fem-1 homolog c (C. elegans) FEM1C 56929 NM_020177 /// XM_005272035 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213342_at AI745185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI745185 /FEA=EST /DB_XREF=gi:5113473 /DB_XREF=est:wg10a05.x1 /CLONE=IMAGE:2364656 /UG=Hs.8939 yes-associated protein 65 kDa /FL=gb:NM_006106.1 AI745185 Yes-associated protein 1 YAP1 10413 NM_001130145 /// NM_001195044 /// NM_001195045 /// NM_001282097 /// NM_001282098 /// NM_001282099 /// NM_001282100 /// NM_001282101 /// NM_006106 /// XM_005271378 /// XM_005271380 /// XM_005271381 /// XM_005271383 0001570 // vasculogenesis // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010837 // regulation of keratinocyte proliferation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation /// 0060242 // contact inhibition // inferred from direct assay /// 0071480 // cellular response to gamma radiation // inferred from direct assay /// 0072091 // regulation of stem cell proliferation // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 213343_s_at AL041124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL041124 /FEA=EST /DB_XREF=gi:5410060 /DB_XREF=est:DKFZp434D0316_s1 /CLONE=DKFZp434D0316 /UG=Hs.6748 hypothetical protein PP1665 AL041124 glycerophosphodiester phosphodiesterase domain containing 5 GDPD5 81544 NM_030792 /// XM_006718694 /// XM_006718695 /// XM_006718696 /// XM_006718697 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213344_s_at H51429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H51429 /FEA=EST /DB_XREF=gi:991270 /DB_XREF=est:yo31f04.s1 /CLONE=IMAGE:179551 /UG=Hs.147097 H2A histone family, member X H51429 H2A histone family, member X H2AFX 3014 NM_002105 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // non-traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010212 // response to ionizing radiation // non-traceable author statement /// 0045739 // positive regulation of DNA repair // non-traceable author statement 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213345_at AI624015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI624015 /FEA=EST /DB_XREF=gi:4648946 /DB_XREF=est:ts25f03.x1 /CLONE=IMAGE:2229629 /UG=Hs.77810 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 AI624015 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 NFATC4 4776 NM_001136022 /// NM_001198965 /// NM_001198966 /// NM_001198967 /// NM_001288802 /// NM_004554 /// XM_006720153 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation 213346_at BE748563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE748563 /FEA=EST /DB_XREF=gi:10162555 /DB_XREF=est:601571521T1 /CLONE=IMAGE:3838541 /UG=Hs.13413 Homo sapiens clone 24463 mRNA sequence BE748563 testis expressed 30 TEX30 93081 NM_001286775 /// NM_001286776 /// NM_138779 /// NR_104590 /// XM_005254097 0016787 // hydrolase activity // inferred from electronic annotation 213347_x_at AW132023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW132023 /FEA=EST /DB_XREF=gi:6133630 /DB_XREF=est:xe71b05.x1 /CLONE=IMAGE:2613297 /UG=Hs.108124 ribosomal protein S4, X-linked AW132023 ribosomal protein S4, X-linked RPS4X 6191 NM_001007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005844 // polysome // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213348_at N33167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N33167 /FEA=EST /DB_XREF=gi:1153566 /DB_XREF=est:yy35b09.s1 /CLONE=IMAGE:273209 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) N33167 cyclin-dependent kinase inhibitor 1C (p57, Kip2) CDKN1C 1028 NM_000076 /// NM_001122630 /// NM_001122631 /// XM_005252731 /// XM_005252732 /// XM_006725125 /// XM_006725126 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000080 // mitotic G1 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 213349_at AI934469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI934469 /FEA=EST /DB_XREF=gi:5673429 /DB_XREF=est:wp58d01.x1 /CLONE=IMAGE:2465953 /UG=Hs.179507 KIAA0779 protein AI934469 transmembrane and coiled-coil domain family 1 TMCC1 23023 NM_001017395 /// NM_001128224 /// NM_015008 /// NR_033361 /// XM_006713542 /// XM_006713543 /// XM_006713544 /// XM_006713545 /// XM_006713546 /// XM_006713547 /// XM_006713548 /// XM_006713549 /// XM_006713550 /// XM_006713551 /// XM_006713552 /// XM_006713553 /// XM_006713554 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213350_at BF680255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF680255 /FEA=EST /DB_XREF=gi:11954150 /DB_XREF=est:602155016F1 /CLONE=IMAGE:4296050 /UG=Hs.182740 ribosomal protein S11 BF680255 ribosomal protein S11 RPS11 6205 NM_001015 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213351_s_at AB018322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018322.1 /DEF=Homo sapiens mRNA for KIAA0779 protein, partial cds. /FEA=mRNA /GEN=KIAA0779 /PROD=KIAA0779 protein /DB_XREF=gi:3882278 /UG=Hs.179507 KIAA0779 protein AB018322 transmembrane and coiled-coil domain family 1 TMCC1 23023 NM_001017395 /// NM_001128224 /// NM_015008 /// NR_033361 /// XM_006713542 /// XM_006713543 /// XM_006713544 /// XM_006713545 /// XM_006713546 /// XM_006713547 /// XM_006713548 /// XM_006713549 /// XM_006713550 /// XM_006713551 /// XM_006713552 /// XM_006713553 /// XM_006713554 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213352_at AB018322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018322.1 /DEF=Homo sapiens mRNA for KIAA0779 protein, partial cds. /FEA=mRNA /GEN=KIAA0779 /PROD=KIAA0779 protein /DB_XREF=gi:3882278 /UG=Hs.179507 KIAA0779 protein AB018322 transmembrane and coiled-coil domain family 1 TMCC1 23023 NM_001017395 /// NM_001128224 /// NM_015008 /// NR_033361 /// XM_006713542 /// XM_006713543 /// XM_006713544 /// XM_006713545 /// XM_006713546 /// XM_006713547 /// XM_006713548 /// XM_006713549 /// XM_006713550 /// XM_006713551 /// XM_006713552 /// XM_006713553 /// XM_006713554 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213353_at BF693921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF693921 /FEA=EST /DB_XREF=gi:11979329 /DB_XREF=est:602082488F1 /CLONE=IMAGE:4246917 /UG=Hs.180513 ATP-binding cassette, sub-family A (ABC1), member 5 BF693921 ATP-binding cassette, sub-family A (ABC1), member 5 ABCA5 23461 NM_018672 /// NM_172232 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0033344 // cholesterol efflux // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0043691 // reverse cholesterol transport // inferred by curator 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 213354_s_at AI935343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935343 /FEA=EST /DB_XREF=gi:5674213 /DB_XREF=est:wo82c12.x1 /CLONE=IMAGE:2461846 /UG=Hs.239752 nuclear receptor subfamily 2, group F, member 6 AI935343 nuclear receptor subfamily 2, group F, member 6 NR2F6 2063 NM_005234 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043153 // entrainment of circadian clock by photoperiod // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 213355_at AI989567 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI989567 /FEA=EST /DB_XREF=gi:5836448 /DB_XREF=est:ws34e03.x1 /CLONE=IMAGE:2499100 /UG=Hs.34578 alpha2,3-sialyltransferase AI989567 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 ST3GAL6 10402 NM_001271142 /// NM_001271145 /// NM_001271146 /// NM_001271147 /// NM_001271148 /// NM_006100 /// XM_005247067 /// XM_005247068 /// XM_005247069 /// XM_005247070 /// XM_005247071 /// XM_005247072 /// XM_006713474 /// XM_006713475 /// XM_006713476 /// XR_427357 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052798 // beta-galactoside alpha-2,3-sialyltransferase activity // inferred from direct assay 213356_x_at AL568186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568186 /FEA=EST /DB_XREF=gi:12922280 /DB_XREF=est:AL568186 /CLONE=CS0DF035YA23 (3 prime) /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 AL568186 heterogeneous nuclear ribonucleoprotein A1 /// heterogeneous nuclear ribonucleoprotein A1-like 2 /// heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 /// heterogeneous nuclear ribonucleoprotein A1 pseudogene 33 HNRNPA1 /// HNRNPA1L2 /// HNRNPA1P10 /// HNRNPA1P33 3178 /// 144983 /// 664709 /// 728643 NM_001011724 /// NM_001011725 /// NM_002136 /// NM_031157 /// NR_002944 /// NR_003277 /// XM_005268826 /// XR_245923 /// XR_245924 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213357_at AV701318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV701318 /FEA=EST /DB_XREF=gi:10717648 /DB_XREF=est:AV701318 /CLONE=ADAAGD10 /UG=Hs.278626 ArgAbl-interacting protein ArgBP2 AV701318 general transcription factor IIH, polypeptide 5 GTF2H5 404672 NM_207118 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 213358_at AB018345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018345.1 /DEF=Homo sapiens mRNA for KIAA0802 protein, partial cds. /FEA=mRNA /GEN=KIAA0802 /PROD=KIAA0802 protein /DB_XREF=gi:3882324 /UG=Hs.27657 KIAA0802 protein AB018345 microtubule crosslinking factor 1 MTCL1 23255 NM_015210 /// XM_005258098 /// XM_005258099 /// XM_006722318 /// XM_006722319 /// XM_006722320 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0010506 // regulation of autophagy // inferred from electronic annotation /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from sequence or structural similarity /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 2000576 // positive regulation of microtubule motor activity // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from sequence or structural similarity /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from direct assay /// 0097427 // microtubule bundle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 213359_at W74620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W74620 /FEA=EST /DB_XREF=gi:1384833 /DB_XREF=est:zd77e04.s1 /CLONE=IMAGE:346686 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) W74620 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213360_s_at AA514622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA514622 /FEA=EST /DB_XREF=gi:2254222 /DB_XREF=est:nf55c12.s1 /CLONE=IMAGE:923830 /UG=Hs.295112 KIAA0618 gene product AA514622 POM121 transmembrane nucleoporin /// POM121 transmembrane nucleoporin C POM121 /// POM121C 9883 /// 100101267 NM_001099415 /// NM_001257190 /// NM_172020 /// XM_005250082 /// XM_005250726 /// XM_005250727 /// XM_005250728 /// XM_005250729 /// XM_005250730 /// XM_005250731 /// XM_005250732 /// XM_006716194 /// XM_006716195 /// XM_006716196 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213361_at AW129593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW129593 /FEA=EST /DB_XREF=gi:6117537 /DB_XREF=est:xe19e10.x1 /CLONE=IMAGE:2607594 /UG=Hs.283761 tudor repeat associator with PCTAIRE 2 AW129593 tudor domain containing 7 TDRD7 23424 NM_014290 /// XM_006717025 /// XM_006717026 0002089 // lens morphogenesis in camera-type eye // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0010608 // posttranscriptional regulation of gene expression // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0035770 // ribonucleoprotein granule // inferred from direct assay /// 0043186 // P granule // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from electronic annotation 213362_at N73931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N73931 /FEA=EST /DB_XREF=gi:1231216 /DB_XREF=est:za74a07.s1 /CLONE=IMAGE:298260 /UG=Hs.323079 Homo sapiens mRNA; cDNA DKFZp564P116 (from clone DKFZp564P116) N73931 protein tyrosine phosphatase, receptor type, D PTPRD 5789 NM_001040712 /// NM_001171025 /// NM_002839 /// NM_130391 /// NM_130392 /// NM_130393 /// XM_006716813 /// XM_006716814 /// XM_006716815 /// XM_006716816 /// XM_006716817 /// XM_006716818 /// XM_006716819 /// XM_006716820 /// XM_006716821 /// XM_006716822 /// XM_006716823 /// XM_006716824 /// XM_006716825 /// XM_006716826 /// XM_006716827 /// XM_006716828 /// XM_006716829 /// XM_006716830 /// XM_006716831 /// XM_006716832 /// XM_006716833 /// XM_006716834 /// XM_006716835 /// XM_006716836 /// XM_006716837 /// XM_006716838 /// XM_006716839 0006470 // protein dephosphorylation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // non-traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 213363_at AW170549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW170549 /FEA=EST /DB_XREF=gi:6402074 /DB_XREF=est:xn63d04.x1 /CLONE=IMAGE:2698375 /UG=Hs.31535 hypothetical protein PRO2325 AW170549 carbonic anhydrase VB pseudogene 1 CA5BP1 340591 NR_026551 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 213364_s_at AI052536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI052536 /FEA=EST /DB_XREF=gi:3308527 /DB_XREF=est:oz27g09.x1 /CLONE=IMAGE:1676608 /UG=Hs.31834 Homo sapiens clone 25129 mRNA sequence AI052536 sorting nexin 1 SNX1 6642 NM_001242933 /// NM_003099 /// NM_148955 /// NM_152826 /// XM_005254610 /// XM_005254611 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 213365_at N64622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N64622 /FEA=EST /DB_XREF=gi:1212451 /DB_XREF=est:yz86f08.s1 /CLONE=IMAGE:289959 /UG=Hs.157426 KIAA1504 protein N64622 ERI1 exoribonuclease family member 2 ERI2 112479 NM_001142725 /// NM_080663 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213366_x_at AV711183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV711183 /FEA=EST /DB_XREF=gi:10730489 /DB_XREF=est:AV711183 /CLONE=CuAAOG09 /UG=Hs.155433 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 AV711183 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 ATP5C1 509 NM_001001973 /// NM_005174 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred by curator /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 213367_at AF035281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035281.1 /DEF=Homo sapiens clone 23903 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661032 /UG=Hs.12526 Homo sapiens clone 23903 mRNA sequence AF035281 AI894139 pseudogene LOC155060 155060 NR_015357 /// NR_036573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213368_x_at BE501428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE501428 /FEA=EST /DB_XREF=gi:9703836 /DB_XREF=est:hw31f02.x1 /CLONE=IMAGE:3184539 /UG=Hs.109299 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 BE501428 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 PPFIA3 8541 NM_003660 /// NR_103842 /// XM_006723450 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213369_at AI825832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825832 /FEA=EST /DB_XREF=gi:5446503 /DB_XREF=est:td19b04.x1 /CLONE=IMAGE:2076079 /UG=Hs.137556 Homo sapiens mRNA; cDNA DKFZp434A132 (from clone DKFZp434A132) AI825832 cadherin-related family member 1 CDHR1 92211 NM_001171971 /// NM_033100 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213370_s_at BF057298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057298 /FEA=EST /DB_XREF=gi:10811194 /DB_XREF=est:7k18g10.x1 /CLONE=IMAGE:3444691 /UG=Hs.21695 DKFZP434L243 protein BF057298 Scm-like with four mbt domains 1 SFMBT1 51460 NM_001005158 /// NM_001005159 /// NM_016329 /// XM_005265221 /// XM_006713203 /// XM_006713204 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048635 // negative regulation of muscle organ development // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 213371_at AI803302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803302 /FEA=EST /DB_XREF=gi:5368774 /DB_XREF=est:tc17d10.x1 /CLONE=IMAGE:2064115 /UG=Hs.49998 Z-band alternatively spliced PDZ-motif AI803302 LIM domain binding 3 LDB3 11155 NM_001080114 /// NM_001080115 /// NM_001080116 /// NM_001171610 /// NM_001171611 /// NM_007078 /// XM_005269464 /// XM_005269465 /// XM_005269466 /// XM_005269467 /// XM_005269468 /// XM_006717598 /// XM_006717599 /// XM_006717600 /// XM_006717601 0045214 // sarcomere organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation 213372_at AW173157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW173157 /FEA=EST /DB_XREF=gi:6439105 /DB_XREF=est:xj84a12.x1 /CLONE=IMAGE:2663902 /UG=Hs.26860 Homo sapiens mRNA; cDNA DKFZp586G1922 (from clone DKFZp586G1922) AW173157 progestin and adipoQ receptor family member III PAQR3 152559 NM_001040202 /// NM_177453 /// XM_005262769 /// XM_005262770 /// XM_006714104 /// XM_006714105 /// XM_006714106 /// XM_006714107 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from physical interaction /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // inferred from electronic annotation 213373_s_at BF439983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439983 /FEA=EST /DB_XREF=gi:11452500 /DB_XREF=est:nac51f11.x1 /CLONE=IMAGE:3406220 /UG=Hs.19949 caspase 8, apoptosis-related cysteine protease /FL=gb:U58143.1 BF439983 caspase 8, apoptosis-related cysteine peptidase CASP8 841 NM_001080124 /// NM_001080125 /// NM_001228 /// NM_033355 /// NM_033356 /// NM_033357 /// NM_033358 /// NR_111983 /// XM_005246885 /// XM_005246886 /// XM_005246887 /// XM_005246888 /// XM_005246889 /// XM_005246890 /// XM_005246891 /// XM_005246892 /// XM_005246893 /// XM_005246894 /// XM_005246895 /// XM_005246896 /// XM_006712789 /// XM_006712790 /// XM_006712791 /// XM_006712792 /// XM_006712793 /// XR_241323 0001525 // angiogenesis // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // not recorded /// 0009409 // response to cold // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030101 // natural killer cell activation // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0036462 // TRAIL-activated apoptotic signaling pathway // inferred from direct assay /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype /// 0060715 // syncytiotrophoblast cell differentiation involved in labyrinthine layer development // traceable author statement /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2001233 // regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0030690 // Noc1p-Noc2p complex // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0097199 // cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 213374_x_at AW000964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW000964 /FEA=EST /DB_XREF=gi:5847880 /DB_XREF=est:wr90h10.x1 /CLONE=IMAGE:2495011 /UG=Hs.236642 3-hydroxyisobutyryl-Coenzyme A hydrolase AW000964 3-hydroxyisobutyryl-CoA hydrolase HIBCH 26275 NM_014362 /// NM_198047 0006574 // valine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003860 // 3-hydroxyisobutyryl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 213375_s_at N80918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N80918 /FEA=EST /DB_XREF=gi:1243619 /DB_XREF=est:zb07e02.s1 /CLONE=IMAGE:301370 /UG=Hs.22174 Novel human gene mapping to chomosome 13 N80918 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 213376_at AI656706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI656706 /FEA=EST /DB_XREF=gi:4740685 /DB_XREF=est:tt53e01.x1 /CLONE=IMAGE:2244504 /UG=Hs.24083 KIAA0997 protein AI656706 zinc finger and BTB domain containing 1 ZBTB1 22890 NM_001123329 /// NM_014950 /// XM_005267410 /// XM_005267411 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002711 // positive regulation of T cell mediated immunity // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from direct assay /// 2000176 // positive regulation of pro-T cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 213377_x_at AI799007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799007 /FEA=EST /DB_XREF=gi:5364479 /DB_XREF=est:we97d07.x1 /CLONE=IMAGE:2349037 /UG=Hs.285405 ribosomal protein S12 AI799007 ribosomal protein S12 RPS12 6206 NM_001016 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213378_s_at AI983033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983033 /FEA=EST /DB_XREF=gi:5810252 /DB_XREF=est:wz30a12.x1 /CLONE=IMAGE:2559550 /UG=Hs.27424 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 11 (S.cerevisiae CHL1-like helicase) AI983033 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 /// DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene /// DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11-like DDX11 /// DDX12P /// LOC642846 1663 /// 440081 /// 642846 NM_001257144 /// NM_001257145 /// NM_004399 /// NM_004400 /// NM_030653 /// NM_030655 /// NM_152438 /// NR_024374 /// NR_033399 /// XM_005253331 /// XM_005253333 /// XM_006719041 /// XM_006719042 /// XM_006719043 /// XM_006719044 /// XM_006719045 /// XM_006719046 /// XM_006719047 /// XM_006719048 /// XM_006719049 /// XM_006719050 /// XM_006719051 /// XM_006719052 /// XM_006719053 /// XR_429031 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000084 // mitotic S phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 213379_at AF091086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF091086.1 /DEF=Homo sapiens clone 640 unknown mRNA, complete sequence. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3860009 /UG=Hs.44563 hypothetical protein /FL=gb:NM_015697.1 AF091086 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase COQ2 27235 NM_015697 /// XM_005262926 /// XM_005262927 /// XM_006714182 /// XR_427543 /// XR_427544 0006071 // glycerol metabolic process // inferred from genetic interaction /// 0006744 // ubiquinone biosynthetic process // inferred from direct assay /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from reviewed computational analysis /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from reviewed computational analysis /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0002083 // 4-hydroxybenzoate decaprenyltransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047293 // 4-hydroxybenzoate nonaprenyltransferase activity // inferred from electronic annotation 213380_x_at AA911235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA911235 /FEA=EST /DB_XREF=gi:3050525 /DB_XREF=est:ol49d02.s1 /CLONE=IMAGE:1526787 /UG=Hs.278657 macrophage stimulating 1 (hepatocyte growth factor-like) AA911235 hepatocyte growth factor-like protein-like /// hepatocyte growth factor-like protein-like /// macrophage stimulating 1 (hepatocyte growth factor-like) /// macrophage stimulating 1-like /// macrophage stimulating 1 (hepatocyte growth factor-like) pseudogene 2 LOC101930052 /// LOC102724562 /// MST1 /// MST1L /// MST1P2 4485 /// 11209 /// 11223 /// 101930052 /// 102724562 NM_001271733 /// NM_020998 /// NR_002729 /// NR_027504 /// XM_006713166 /// XM_006713167 /// XM_006713168 /// XM_006713169 /// XR_250701 /// XR_427269 /// XR_427270 /// XR_427271 /// XR_427272 /// XR_427273 /// XR_427274 /// XR_427275 /// XR_427276 /// XR_430575 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213381_at N91149 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N91149 /FEA=EST /DB_XREF=gi:1444476 /DB_XREF=est:zb12a04.s1 /CLONE=IMAGE:301806 /UG=Hs.279639 Homo sapiens mRNA; cDNA DKFZp586M2022 (from clone DKFZp586M2022) N91149 V-set and transmembrane domain containing 4 VSTM4 196740 NM_001031746 /// NM_144984 /// XM_006717689 /// XR_246075 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213382_at AL137798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137798 /DEF=Human DNA sequence from clone RP5-1182A14 on chromosome 1 Contains part of a gene similar to rat Espin, a pseudogene similar to KIAA0454, a gene similar to MST1 (macrophage stimulating 1 (hepatocyte growth factor-like)), a pseudogene similar to KI... /FEA=mRNA_3 /DB_XREF=gi:9187169 /UG=Hs.278657 macrophage stimulating 1 (hepatocyte growth factor-like) AL137798 macrophage stimulating 1-like MST1L 11223 NM_001271733 /// NR_002729 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213383_at AW593269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW593269 /FEA=EST /DB_XREF=gi:7280527 /DB_XREF=est:hg11h06.x1 /CLONE=IMAGE:2945339 /UG=Hs.296406 KIAA0685 gene product AW593269 SET binding factor 1 SBF1 6305 NM_002972 /// XM_005261931 /// XM_005261932 /// XM_005261934 /// XM_005261935 0006470 // protein dephosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 213384_x_at Z37544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z37544 /DEF=H.sapiens gene for phospholipase C beta 3, exon 1 /FEA=mRNA /DB_XREF=gi:609185 /UG=Hs.37121 phospholipase C, beta 3 (phosphatidylinositol-specific) Z37544 phospholipase C, beta 3 (phosphatidylinositol-specific) PLCB3 5331 NM_000932 /// NM_001184883 /// XM_005274052 0003073 // regulation of systemic arterial blood pressure // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213385_at AK026415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026415.1 /DEF=Homo sapiens cDNA: FLJ22762 fis, clone KAIA0960, highly similar to HUMB2CHIM Homo sapiens beta2-chimaerin mRNA. /FEA=mRNA /DB_XREF=gi:10439275 /UG=Hs.286055 chimerin (chimaerin) 2 AK026415 chimerin 2 CHN2 1124 NM_001039936 /// NM_001293069 /// NM_001293070 /// NM_001293071 /// NM_001293072 /// NM_001293073 /// NM_001293075 /// NM_001293076 /// NM_001293077 /// NM_001293078 /// NM_001293079 /// NM_001293080 /// NM_001293081 /// NM_004067 /// NR_120524 /// NR_120525 /// XM_005249599 /// XM_005249602 /// XR_171041 /// XR_171649 /// XR_172478 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213386_at AV726900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV726900 /FEA=EST /DB_XREF=gi:10836321 /DB_XREF=est:AV726900 /CLONE=HTCABD05 /UG=Hs.7000 ESTs AV726900 transmembrane protein 246 TMEM246 84302 NM_032342 /// XM_005252275 /// XM_005252276 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213387_at AB033066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033066.1 /DEF=Homo sapiens mRNA for KIAA1240 protein, partial cds. /FEA=mRNA /GEN=KIAA1240 /PROD=KIAA1240 protein /DB_XREF=gi:6330790 /UG=Hs.62576 KIAA1240 protein AB033066 ATPase family, AAA domain containing 2B ATAD2B 54454 NM_001242338 /// NM_017552 /// XM_005264372 /// XM_005264373 /// XM_006712030 /// XM_006712031 /// XM_006712032 /// XM_006712033 /// XR_426984 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 213388_at H15535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H15535 /FEA=EST /DB_XREF=gi:880355 /DB_XREF=est:ym27c01.s1 /CLONE=IMAGE:49385 /UG=Hs.52792 Homo sapiens mRNA; cDNA DKFZp586I1823 (from clone DKFZp586I1823) H15535 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 213389_at BF508616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508616 /FEA=EST /DB_XREF=gi:11591914 /DB_XREF=est:UI-H-BI4-aoo-g-08-0-UI.s1 /CLONE=IMAGE:3085646 /UG=Hs.79347 KIAA0211 gene product BF508616 zinc finger protein 592 ZNF592 9640 NM_014630 /// XM_005254996 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213390_at AB028987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028987.1 /DEF=Homo sapiens mRNA for KIAA1064 protein, partial cds. /FEA=mRNA /GEN=KIAA1064 /PROD=KIAA1064 protein /DB_XREF=gi:5689464 /UG=Hs.72134 KIAA1064 protein AB028987 zinc finger CCCH-type containing 4 ZC3H4 23211 NM_015168 /// XM_005258676 /// XM_005258677 /// XM_005258678 /// XM_006723113 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213391_at AI669947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI669947 /FEA=EST /DB_XREF=gi:4834721 /DB_XREF=est:wb86d12.x1 /CLONE=IMAGE:2312567 /UG=Hs.71969 Homo sapiens mRNA; cDNA DKFZp564P0823 (from clone DKFZp564P0823) AI669947 dpy-19-like 4 (C. elegans) DPY19L4 286148 NM_181787 /// XM_005250894 /// XM_005250895 /// XM_005250896 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 213392_at AW070229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW070229 /FEA=EST /DB_XREF=gi:6025227 /DB_XREF=est:xa09e01.x1 /CLONE=IMAGE:2567832 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B AW070229 IQ motif containing K IQCK 124152 NM_153208 /// XM_006721019 /// XR_243261 213393_at AI767210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767210 /FEA=EST /DB_XREF=gi:5233719 /DB_XREF=est:wi94d05.x1 /CLONE=IMAGE:2400969 /UG=Hs.90449 Human clone 23908 mRNA sequence AI767210 major facilitator superfamily domain containing 9 MFSD9 84804 NM_032718 /// XM_005264032 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 213394_at AI674759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI674759 /FEA=EST /DB_XREF=gi:4875239 /DB_XREF=est:wd20b03.x1 /CLONE=IMAGE:2328653 /UG=Hs.259729 KIAA0596 protein AI674759 mitogen-activated protein kinase binding protein 1 MAPKBP1 23005 NM_001128608 /// NM_001265611 /// NM_014994 /// NR_049761 /// NR_049762 /// XM_006720438 /// XM_006720439 0007256 // activation of JNKK activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 213395_at AL022327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022327 /DEF=Human DNA sequence from clone RP3-355C18 on chromosome 22q13.3 Contains the KIAA0027 gene, ESTs, STSs, GSSs and seven putative CpG islands /FEA=mRNA /DB_XREF=gi:5304851 /UG=Hs.74518 KIAA0027 protein AL022327 megalencephalic leukoencephalopathy with subcortical cysts 1 MLC1 23209 NM_015166 /// NM_139202 /// XR_430476 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0032388 // positive regulation of intracellular transport // inferred from direct assay /// 0047484 // regulation of response to osmotic stress // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity /// 0072584 // caveolin-mediated endocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from sequence or structural similarity 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay 213396_s_at AA456929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA456929 /FEA=EST /DB_XREF=gi:2179649 /DB_XREF=est:aa90c03.s1 /CLONE=IMAGE:838564 /UG=Hs.75456 A kinase (PRKA) anchor protein 10 AA456929 A kinase (PRKA) anchor protein 10 AKAP10 11216 NM_007202 /// XM_006721431 /// XM_006721432 /// XM_006721433 /// XR_243536 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation 213397_x_at AI761728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761728 /FEA=EST /DB_XREF=gi:5177484 /DB_XREF=est:wg67f03.x1 /CLONE=IMAGE:2370173 /UG=Hs.74711 DnaJ (Hsp40) homolog, subfamily C, member 8 AI761728 ribonuclease, RNase A family, 4 RNASE4 6038 NM_001282192 /// NM_001282193 /// NM_002937 /// NM_194430 /// NM_194431 0001525 // angiogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // traceable author statement /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001556 // oocyte maturation // non-traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // non-traceable author statement /// 0001890 // placenta development // non-traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006379 // mRNA cleavage // non-traceable author statement /// 0006651 // diacylglycerol biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from mutant phenotype /// 0009725 // response to hormone // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032148 // activation of protein kinase B activity // inferred from mutant phenotype /// 0032431 // activation of phospholipase A2 activity // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042592 // homeostatic process // non-traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // non-traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032311 // angiogenin-PRI complex // inferred from physical interaction /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004522 // pancreatic ribonuclease activity // non-traceable author statement /// 0004540 // ribonuclease activity // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation /// 0019843 // rRNA binding // traceable author statement /// 0042277 // peptide binding // inferred from direct assay 213398_s_at AI347090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI347090 /FEA=EST /DB_XREF=gi:4084296 /DB_XREF=est:qp60d11.x1 /CLONE=IMAGE:1927413 /UG=Hs.7911 KIAA0323 protein AI347090 short chain dehydrogenase/reductase family 39U, member 1 SDR39U1 56948 NM_001290292 /// NM_001290293 /// NM_020195 /// XM_005267873 /// XM_006720207 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 213399_x_at AI560720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI560720 /FEA=EST /DB_XREF=gi:4511061 /DB_XREF=est:tq55e12.x1 /CLONE=IMAGE:2212750 /UG=Hs.75722 ribophorin II AI560720 ribophorin II RPN2 6185 NM_001135771 /// NM_002951 /// XM_005260491 /// XM_006723849 /// XM_006723850 /// XM_006723851 /// XM_006723852 0006412 // translation // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation 213400_s_at AV753028 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV753028 /FEA=EST /DB_XREF=gi:10910876 /DB_XREF=est:AV753028 /CLONE=NPDBCD07 /UG=Hs.76536 transducin (beta)-like 1 AV753028 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213401_s_at AA724134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA724134 /FEA=EST /DB_XREF=gi:2741841 /DB_XREF=est:ai07b03.s1 /CLONE=1342061 /UG=Hs.76536 transducin (beta)-like 1 AA724134 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213402_at AA029811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA029811 /FEA=EST /DB_XREF=gi:1496048 /DB_XREF=est:zk07e10.s1 /CLONE=IMAGE:469866 /UG=Hs.79531 Homo sapiens TTF-I interacting peptide 20 mRNA, partial cds AA029811 zinc finger protein 787 ZNF787 126208 NM_001002836 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213403_at BF223370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223370 /FEA=EST /DB_XREF=gi:11130547 /DB_XREF=est:7q87e03.x1 /CLONE=IMAGE:3705316 /UG=Hs.90449 Human clone 23908 mRNA sequence BF223370 major facilitator superfamily domain containing 9 MFSD9 84804 NM_032718 /// XM_005264032 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 213404_s_at BF033683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF033683 /FEA=EST /DB_XREF=gi:10741395 /DB_XREF=est:601453992F1 /CLONE=IMAGE:3857711 /UG=Hs.279903 Ras homolog enriched in brain 2 BF033683 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213405_at N95443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N95443 /FEA=EST /DB_XREF=gi:1267753 /DB_XREF=est:zb81c12.s1 /CLONE=IMAGE:310006 /UG=Hs.19180 Homo sapiens mRNA; cDNA DKFZp564E122 (from clone DKFZp564E122) N95443 RAB22A, member RAS oncogene family RAB22A 57403 NM_020673 /// XM_005260469 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from expression pattern /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 213406_at AA521269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521269 /FEA=EST /DB_XREF=gi:2261812 /DB_XREF=est:aa75f05.s1 /CLONE=IMAGE:826785 /UG=Hs.187991 DKFZP564A122 protein AA521269 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213407_at AB023148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023148.1 /DEF=Homo sapiens mRNA for KIAA0931 protein, partial cds. /FEA=mRNA /GEN=KIAA0931 /PROD=KIAA0931 protein /DB_XREF=gi:4589505 /UG=Hs.173373 KIAA0931 protein AB023148 PH domain and leucine rich repeat protein phosphatase 2 PHLPP2 23035 NM_001289003 /// NM_015020 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213408_s_at AK024034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024034.1 /DEF=Homo sapiens cDNA FLJ13972 fis, clone Y79AA1001548, highly similar to PHOSPHATIDYLINOSITOL 4-KINASE ALPHA (EC 2.7.1.67). /FEA=mRNA /DB_XREF=gi:10436297 /UG=Hs.171625 phosphatidylinositol 4-kinase, catalytic, alpha polypeptide AK024034 phosphatidylinositol 4-kinase, catalytic, alpha /// phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 /// phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 PI4KA /// PI4KAP1 /// PI4KAP2 5297 /// 375133 /// 728233 NM_002650 /// NM_058004 /// NR_003563 /// NR_003700 /// XM_005261634 /// XM_005261635 /// XR_249020 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 213409_s_at BF593727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593727 /FEA=EST /DB_XREF=gi:11686051 /DB_XREF=est:nac06b11.x1 /CLONE=IMAGE:3276261 /UG=Hs.279903 Ras homolog enriched in brain 2 BF593727 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213410_at AL050102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050102.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1019 (from clone DKFZp586F1019); partial cds. /FEA=mRNA /GEN=DKFZp586F1019 /PROD=hypothetical protein /DB_XREF=gi:4884131 /UG=Hs.227209 DKFZP586F1019 protein AL050102 erythroid differentiation regulatory factor 1 EDRF1 26098 NM_001202438 /// NM_015608 /// NM_030897 /// NR_110857 /// NR_110858 /// NR_110859 /// XM_005269687 /// XM_005269688 /// XM_005269689 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 213411_at AW242701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242701 /FEA=EST /DB_XREF=gi:6576546 /DB_XREF=est:xm90a08.x1 /CLONE=IMAGE:2691446 /UG=Hs.256398 Homo sapiens mRNA; cDNA DKFZp434E0528 (from clone DKFZp434E0528) AW242701 ADAM metallopeptidase domain 22 ADAM22 53616 NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 213412_at NM_014428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014428.1 /DEF=Homo sapiens tight junction protein 3 (zona occludens 3) (TJP3), mRNA. /FEA=CDS /GEN=TJP3 /PROD=tight junction protein 3 (zona occludens 3) /DB_XREF=gi:10092690 /UG=Hs.25527 tight junction protein 3 (zona occludens 3) /FL=gb:NM_014428.1 NM_014428 tight junction protein 3 TJP3 27134 NM_001267560 /// NM_001267561 /// NM_014428 /// XM_005259539 /// XM_006722724 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213413_at BG434174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG434174 /FEA=EST /DB_XREF=gi:13340680 /DB_XREF=est:602506106F1 /CLONE=IMAGE:4603513 /UG=Hs.23437 Homo sapiens cDNA FLJ13555 fis, clone PLACE1007677 BG434174 stonin 1 STON1 11037 NM_001198595 /// NM_006873 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005672 // transcription factor TFIIA complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 213414_s_at BE259729 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE259729 /FEA=EST /DB_XREF=gi:9130437 /DB_XREF=est:601145954F1 /CLONE=IMAGE:3161244 /UG=Hs.298262 ribosomal protein S19 BE259729 ribosomal protein S19 RPS19 6223 NM_001022 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007000 // nucleolus organization // inferred from mutant phenotype /// 0009991 // response to extracellular stimulus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0051272 // positive regulation of cellular component movement // traceable author statement /// 0060265 // positive regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213415_at AI768628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768628 /FEA=EST /DB_XREF=gi:5235137 /DB_XREF=est:wh24b11.x1 /CLONE=IMAGE:2381661 /UG=Hs.54570 chloride intracellular channel 2 /FL=gb:NM_001289.2 AI768628 chloride intracellular channel 2 CLIC2 1193 NM_001289 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0004364 // glutathione transferase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213416_at BG532690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG532690 /FEA=EST /DB_XREF=gi:13524229 /DB_XREF=est:602580263F1 /CLONE=IMAGE:4718390 /UG=Hs.40034 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) BG532690 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) ITGA4 3676 NM_000885 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0060324 // face development // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0090074 // negative regulation of protein homodimerization activity // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 213417_at AW173045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW173045 /FEA=EST /DB_XREF=gi:6438993 /DB_XREF=est:xj82e03.x1 /CLONE=IMAGE:2663740 /UG=Hs.322856 Homo sapiens cDNA FLJ10169 fis, clone HEMBA1003662, highly similar to TBX2 PROTEIN AW173045 T-box 2 TBX2 6909 NM_005994 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048596 // embryonic camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060465 // pharynx development // inferred from sequence or structural similarity /// 0060560 // developmental growth involved in morphogenesis // inferred from electronic annotation /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 1901208 // negative regulation of heart looping // inferred from sequence or structural similarity /// 1901211 // negative regulation of cardiac chamber formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 213418_at NM_002155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002155.1 /DEF=Homo sapiens heat shock 70kD protein 6 (HSP70B) (HSPA6), mRNA. /FEA=CDS /GEN=HSPA6 /PROD=heat shock 70kD protein 6 (HSP70B) /DB_XREF=gi:4504514 /UG=Hs.3268 heat shock 70kD protein 6 (HSP70B) /FL=gb:NM_002155.1 NM_002155 heat shock 70kDa protein 6 (HSP70B') HSPA6 3310 NM_002155 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0070370 // cellular heat acclimation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 213419_at U62325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U62325.1 /DEF=Human FE65-like protein (hFE65L) mRNA, partial cds. /FEA=mRNA /GEN=hFE65L /PROD=FE65-like protein /DB_XREF=gi:1657751 /UG=Hs.324125 amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) U62325 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 213420_at AA100250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA100250 /FEA=EST /DB_XREF=gi:1647823 /DB_XREF=est:zn41d10.s1 /CLONE=IMAGE:550003 /UG=Hs.90869 Homo sapiens clones 24622 and 24623 mRNA sequence AA100250 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 DHX57 90957 NM_198963 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213421_x_at AW007273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007273 /FEA=EST /DB_XREF=gi:5856051 /DB_XREF=est:wt54d10.x1 /CLONE=IMAGE:2511283 /UG=Hs.58247 protease, serine, 4 (trypsin 4, brain) AW007273 protease, serine, 3 PRSS3 5646 NM_001197097 /// NM_001197098 /// NM_002771 /// NM_007343 /// XM_005251519 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // traceable author statement /// 0009235 // cobalamin metabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213422_s_at AW888223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW888223 /FEA=EST /DB_XREF=gi:8050234 /DB_XREF=est:MXRA8 /CLONE=Incyte 3948614 /UG=Hs.59384 Homo sapiens mRNA; cDNA DKFZp586E2023 (from clone DKFZp586E2023) AW888223 matrix-remodelling associated 8 MXRA8 54587 NM_001282582 /// NM_001282583 /// NM_001282584 /// NM_001282585 /// NM_032348 /// XM_005244758 /// XM_006710702 0060857 // establishment of glial blood-brain barrier // inferred from sequence or structural similarity 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 213423_x_at AI884858 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI884858 /FEA=EST /DB_XREF=gi:5590022 /DB_XREF=est:wl85f06.x1 /CLONE=IMAGE:2431715 /UG=Hs.71119 Putative prostate cancer tumor suppressor AI884858 tumor suppressor candidate 3 TUSC3 7991 NM_006765 /// NM_178234 /// XM_005273646 /// XM_005273647 /// XM_005273648 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from genetic interaction /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype 213424_at AB020702 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020702.1 /DEF=Homo sapiens mRNA for KIAA0895 protein, partial cds. /FEA=mRNA /GEN=KIAA0895 /PROD=KIAA0895 protein /DB_XREF=gi:4240278 /UG=Hs.6224 KIAA0895 protein AB020702 KIAA0895 KIAA0895 23366 NM_001100425 /// NM_001199706 /// NM_001199707 /// NM_001199708 /// NM_015314 /// XM_005249688 /// XM_005249689 /// XM_005249690 /// XM_006715678 /// XM_006715679 213425_at AI968085 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI968085 /FEA=EST /DB_XREF=gi:5764903 /DB_XREF=est:wu12h08.x1 /CLONE=IMAGE:2516799 /UG=Hs.152213 wingless-type MMTV integration site family, member 5A AI968085 wingless-type MMTV integration site family, member 5A WNT5A 7474 NM_001256105 /// NM_003392 /// XM_006713324 0000187 // activation of MAPK activity // inferred from direct assay /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001736 // establishment of planar polarity // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from expression pattern /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002741 // positive regulation of cytokine secretion involved in immune response // inferred from mutant phenotype /// 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0003344 // pericardium morphogenesis // inferred from electronic annotation /// 0003401 // axis elongation // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from direct assay /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from mutant phenotype /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0007257 // activation of JUN kinase activity // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007442 // hindgut morphogenesis // inferred from electronic annotation /// 0007494 // midgut development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008595 // anterior/posterior axis specification, embryo // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from expression pattern /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0021891 // olfactory bulb interneuron development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030825 // positive regulation of cGMP metabolic process // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045778 // positive regulation of ossification // inferred from mutant phenotype /// 0045836 // positive regulation of meiosis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048850 // hypophysis morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0050729 // positive regulation of inflammatory response // inferred from mutant phenotype /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0060021 // palate development // inferred from mutant phenotype /// 0060026 // convergent extension // inferred from electronic annotation /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060065 // uterus development // inferred from electronic annotation /// 0060067 // cervix development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060324 // face development // inferred from mutant phenotype /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from direct assay /// 0060599 // lateral sprouting involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060606 // tube closure // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0060686 // negative regulation of prostatic bud formation // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0060760 // positive regulation of response to cytokine stimulus // inferred from direct assay /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from mutant phenotype /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0061347 // planar cell polarity pathway involved in outflow tract morphogenesis // inferred from electronic annotation /// 0061348 // planar cell polarity pathway involved in ventricular septum morphogenesis // inferred from electronic annotation /// 0061349 // planar cell polarity pathway involved in cardiac right atrium morphogenesis // inferred from electronic annotation /// 0061350 // planar cell polarity pathway involved in cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0061354 // planar cell polarity pathway involved in pericardium morphogenesis // inferred from electronic annotation /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0071219 // cellular response to molecule of bacterial origin // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0071277 // cellular response to calcium ion // inferred from expression pattern /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0072201 // negative regulation of mesenchymal cell proliferation // inferred from direct assay /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred from electronic annotation /// 2000484 // positive regulation of interleukin-8 secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005110 // frizzled-2 binding // inferred from electronic annotation /// 0005115 // receptor tyrosine kinase-like orphan receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0048018 // receptor agonist activity // inferred by curator 213426_s_at AA150110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA150110 /FEA=EST /DB_XREF=gi:1721541 /DB_XREF=est:zl06b01.s1 /CLONE=IMAGE:491497 /UG=Hs.139851 caveolin 2 AA150110 caveolin 2 CAV2 858 NM_001206747 /// NM_001206748 /// NM_001233 /// NM_198212 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from expression pattern /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0070836 // caveola assembly // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from electronic annotation 213427_at NM_006638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006638.1 /DEF=Homo sapiens ribonuclease P, 40kD subunit (RPP40), mRNA. /FEA=CDS /GEN=RPP40 /PROD=ribonuclease P, 40kD subunit /DB_XREF=gi:5730016 /UG=Hs.115823 ribonuclease P, 40kD subunit /FL=gb:NM_006638.1 NM_006638 ribonuclease P/MRP 40kDa subunit RPP40 10799 NM_001286132 /// NM_001286133 /// NM_006638 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005634 // nucleus // traceable author statement /// 0005655 // nucleolar ribonuclease P complex // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213428_s_at AA292373 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA292373 /FEA=EST /DB_XREF=gi:1940353 /DB_XREF=est:zt51a09.s1 /CLONE=IMAGE:725848 /UG=Hs.108885 collagen, type VI, alpha 1 AA292373 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 213429_at AW025579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW025579 /FEA=EST /DB_XREF=gi:5879109 /DB_XREF=est:wu75b04.x1 /CLONE=IMAGE:2525839 /UG=Hs.100261 Homo sapiens mRNA; cDNA DKFZp564B222 (from clone DKFZp564B222) AW025579 BicC family RNA binding protein 1 BICC1 80114 NM_001080512 /// XM_005270166 /// XM_005270167 /// XM_005270168 /// XM_005270169 /// XM_005270170 0007275 // multicellular organismal development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213430_at BF224071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224071 /FEA=EST /DB_XREF=gi:11131297 /DB_XREF=est:7q83e03.x1 /CLONE=IMAGE:3704932 /UG=Hs.7972 KIAA0871 protein BF224071 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213431_x_at AB011114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011114.2 /DEF=Homo sapiens mRNA for KIAA0542 protein, partial cds. /FEA=mRNA /GEN=KIAA0542 /PROD=KIAA0542 protein /DB_XREF=gi:6635200 /UG=Hs.62209 KIAA0542 gene product AB011114 Sfi1 homolog, spindle assembly associated (yeast) SFI1 9814 NM_001007467 /// NM_001258325 /// NM_001258326 /// NM_001258327 /// NM_014775 /// XM_005261868 /// XM_005261869 /// XM_005261870 /// XM_005261871 /// XM_005261872 /// XM_005261873 /// XM_005261874 /// XM_006724388 /// XM_006724389 /// XM_006724390 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 213432_at AI697108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI697108 /FEA=EST /DB_XREF=gi:4985008 /DB_XREF=est:tq14g03.x1 /CLONE=IMAGE:2208820 /UG=Hs.102482 mucin 5, subtype B, tracheobronchial AI697108 mucin 5B, oligomeric mucus/gel-forming MUC5B 727897 NM_002458 0007155 // cell adhesion // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213433_at AF038193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF038193.1 /DEF=Homo sapiens clone 23608 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2795913 /UG=Hs.6220 Homo sapiens clone 23608 mRNA sequence AF038193 ADP-ribosylation factor-like 3 ARL3 403 NM_004311 0000910 // cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0042461 // photoreceptor cell development // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213434_at H95263 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H95263 /FEA=EST /DB_XREF=gi:1102896 /DB_XREF=est:yu20e04.s1 /CLONE=IMAGE:234366 /UG=Hs.13431 Homo sapiens clone 24790 mRNA sequence H95263 syntaxin 2 STX2 2054 NM_001980 /// NM_194356 /// XM_005253556 /// XM_005253557 /// XM_006719276 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007340 // acrosome reaction // inferred from sequence or structural similarity /// 0007398 // ectoderm development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype 0005911 // cell-cell junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity 213435_at AB028957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028957.1 /DEF=Homo sapiens mRNA for KIAA1034 protein, partial cds. /FEA=mRNA /GEN=KIAA1034 /PROD=KIAA1034 protein /DB_XREF=gi:5689404 /UG=Hs.12896 KIAA1034 protein AB028957 SATB homeobox 2 SATB2 23314 NM_001172509 /// NM_001172517 /// NM_015265 /// XM_005246396 /// XM_006712372 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213436_at U73304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U73304 /DEF=Human CB1 cannabinoid receptor (CNR1) gene, complete cds /FEA=mRNA /DB_XREF=gi:1657840 /UG=Hs.75110 cannabinoid receptor 1 (brain) U73304 cannabinoid receptor 1 (brain) CNR1 1268 NM_001160226 /// NM_001160258 /// NM_001160259 /// NM_001160260 /// NM_016083 /// NM_033181 /// XM_005248650 /// XM_006715330 0002866 // positive regulation of acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0031622 // positive regulation of fever generation // inferred from electronic annotation /// 0031999 // negative regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033004 // negative regulation of mast cell activation // inferred from electronic annotation /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038171 // cannabinoid signaling pathway // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043271 // negative regulation of ion transport // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045759 // negative regulation of action potential // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 0060405 // regulation of penile erection // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004949 // cannabinoid receptor activity // inferred from direct assay /// 0008144 // drug binding // inferred from electronic annotation 213437_at AA861784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA861784 /FEA=EST /DB_XREF=gi:2953924 /DB_XREF=est:ak35d05.s1 /CLONE=IMAGE:1407945 /UG=Hs.7972 KIAA0871 protein AA861784 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213438_at AA995925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA995925 /FEA=EST /DB_XREF=gi:3182414 /DB_XREF=est:ou93g10.s1 /CLONE=IMAGE:1635426 /UG=Hs.7309 Homo sapiens clone 23741 mRNA sequence AA995925 neurofascin NFASC 23114 NM_001005387 /// NM_001005388 /// NM_001005389 /// NM_001160331 /// NM_001160332 /// NM_001160333 /// NM_015090 /// XM_005244977 /// XM_005244985 /// XM_005244986 /// XM_005244989 /// XM_005244991 /// XM_005244992 /// XM_005244993 /// XM_005244996 /// XM_005244997 /// XM_006711226 /// XM_006711227 /// XM_006711228 /// XM_006711229 /// XM_006711230 /// XM_006711231 /// XM_006711232 /// XM_006711233 /// XM_006711234 /// XM_006711235 /// XM_006711236 0002175 // protein localization to paranode region of axon // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045162 // clustering of voltage-gated sodium channels // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0071205 // protein localization to juxtaparanode region of axon // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0005622 // intracellular // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0033010 // paranodal junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // traceable author statement /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation 213439_x_at AI197870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI197870 /FEA=EST /DB_XREF=gi:3750476 /DB_XREF=est:qi52g09.x1 /CLONE=IMAGE:1860160 /UG=Hs.6755 RaP2 interacting protein 8 AI197870 RUN domain containing 3A RUNDC3A 10900 NM_001144825 /// NM_001144826 /// NM_006695 /// XM_005256963 /// XM_005256964 /// XR_243627 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0030250 // guanylate cyclase activator activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 213440_at AL530264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL530264 /FEA=EST /DB_XREF=gi:12793757 /DB_XREF=est:AL530264 /CLONE=CS0DD009YH19 (3 prime) /UG=Hs.79507 KIAA0582 protein AL530264 RAB1A, member RAS oncogene family RAB1A 5861 NM_004161 /// NM_015543 /// XM_005264468 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030252 // growth hormone secretion // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0072606 // interleukin-8 secretion // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 213441_x_at AI745526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI745526 /FEA=EST /DB_XREF=gi:5113814 /DB_XREF=est:wc34a10.x1 /CLONE=IMAGE:2317050 /UG=Hs.79414 prostate epithelium-specific Ets transcription factor AI745526 SAM pointed domain containing ETS transcription factor SPDEF 25803 NM_001252294 /// NM_012391 /// XM_005248988 /// XM_006715048 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010455 // positive regulation of cell fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213442_x_at AI745526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI745526 /FEA=EST /DB_XREF=gi:5113814 /DB_XREF=est:wc34a10.x1 /CLONE=IMAGE:2317050 /UG=Hs.79414 prostate epithelium-specific Ets transcription factor AI745526 SAM pointed domain containing ETS transcription factor SPDEF 25803 NM_001252294 /// NM_012391 /// XM_005248988 /// XM_006715048 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010455 // positive regulation of cell fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213443_at N36774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36774 /FEA=EST /DB_XREF=gi:1157916 /DB_XREF=est:yy34d02.s1 /CLONE=IMAGE:273123 /UG=Hs.89862 TNFRSF1A-associated via death domain N36774 TNFRSF1A-associated via death domain TRADD 8717 NM_003789 /// NM_153425 /// XM_005256213 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // traceable author statement /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction 213444_at AB011115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011115.1 /DEF=Homo sapiens mRNA for KIAA0543 protein, partial cds. /FEA=mRNA /GEN=KIAA0543 /PROD=KIAA0543 protein /DB_XREF=gi:3043609 /UG=Hs.98507 KIAA0543 protein AB011115 zinc finger protein 862 ZNF862 643641 NM_001099220 /// XM_005250037 /// XM_006716085 /// XR_242186 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 213445_at D63484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D63484.1 /DEF=Human mRNA for KIAA0150 gene, partial cds. /FEA=mRNA /GEN=KIAA0150 /DB_XREF=gi:1469881 /UG=Hs.98508 KIAA0150 protein D63484 zinc finger CCCH-type containing 3 ZC3H3 23144 NM_015117 /// XM_006716530 /// XM_006716531 /// XM_006716532 /// XM_006716533 /// XM_006716534 /// XM_006716535 /// XM_006716536 /// XM_006716537 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 213446_s_at AI679073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI679073 /FEA=EST /DB_XREF=gi:4889255 /DB_XREF=est:tu71g05.x1 /CLONE=IMAGE:2256536 /UG=Hs.1742 IQ motif containing GTPase activating protein 1 AI679073 IQ motif containing GTPase activating protein 1 IQGAP1 8826 NM_003870 /// XM_005254984 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0035305 // negative regulation of dephosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005884 // actin filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 213447_at AI672541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI672541 /FEA=EST /DB_XREF=gi:4852272 /DB_XREF=est:wb32d12.x1 /CLONE=IMAGE:2307383 /UG=Hs.5022 imprinted in Prader-Willi syndrome AI672541 imprinted in Prader-Willi syndrome (non-protein coding) /// uncharacterized LOC101930404 /// Prader Willi/Angelman region RNA, SNRPN neighbor /// small nucleolar RNA, C/D box 107 /// small nucleolar RNA, C/D box 115-13 /// small nucleolar RNA, C/D box 115-26 /// small nucleolar RNA, C/D box 115-7 /// small nucleolar RNA, C/D box 116-22 /// small nucleolar RNA, C/D box 116-28 /// small nucleolar RNA, C/D box 116-4 /// small nuclear ribonucleoprotein polypeptide N IPW /// LOC101930404 /// PWARSN /// SNORD107 /// SNORD115-13 /// SNORD115-26 /// SNORD115-7 /// SNORD116-22 /// SNORD116-28 /// SNORD116-4 /// SNRPN 3653 /// 6638 /// 91380 /// 347746 /// 100033416 /// 100033433 /// 100033444 /// 100033450 /// 100033802 /// 100033820 /// 101930404 NM_003097 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 /// NR_001293 /// NR_003299 /// NR_003305 /// NR_003319 /// NR_003336 /// NR_003343 /// NR_003361 /// NR_022011 /// NR_023915 /// XR_250593 /// XR_426491 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213448_at AI693193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI693193 /FEA=EST /DB_XREF=gi:4970533 /DB_XREF=est:wd68f02.x1 /CLONE=IMAGE:2336763 /UG=Hs.247551 metaxin 1 AI693193 213449_at D31765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D31765.1 /DEF=Human mRNA for KIAA0061 gene, partial cds. /FEA=mRNA /GEN=KIAA0061 /DB_XREF=gi:498155 /UG=Hs.170114 KIAA0061 protein D31765 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) POP1 10940 NM_001145860 /// NM_001145861 /// NM_015029 0001682 // tRNA 5'-leader removal // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0016078 // tRNA catabolic process // inferred from direct assay /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0000172 // ribonuclease MRP complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005655 // nucleolar ribonuclease P complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation 0000171 // ribonuclease MRP activity // inferred from direct assay /// 0004526 // ribonuclease P activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213450_s_at AI659611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659611 /FEA=EST /DB_XREF=gi:4763181 /DB_XREF=est:tu06a12.x1 /CLONE=IMAGE:2250238 /UG=Hs.14155 KIAA0653 protein, B7-like protein AI659611 inducible T-cell co-stimulator ligand ICOSLG 23308 NM_001283050 /// NM_001283051 /// NM_001283052 /// NM_015259 /// XM_005261098 0002376 // immune system process // inferred from electronic annotation /// 0006952 // defense response // non-traceable author statement /// 0006972 // hyperosmotic response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 213451_x_at BE044614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE044614 /FEA=EST /DB_XREF=gi:8361667 /DB_XREF=est:hq87a07.x1 /CLONE=IMAGE:3126324 /UG=Hs.169886 tenascin XB BE044614 tenascin XA (pseudogene) /// tenascin XB TNXA /// TNXB 7146 /// 7148 NM_007116 /// NM_019105 /// NM_032470 /// NR_001284 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 213452_at AI811577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI811577 /FEA=EST /DB_XREF=gi:5398143 /DB_XREF=est:tw74g05.x1 /CLONE=IMAGE:2265464 /UG=Hs.158174 zinc finger protein 184 (Kruppel-like) AI811577 zinc finger protein 184 ZNF184 7738 NM_007149 /// XM_005249379 /// XM_005249380 /// XM_006715181 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213453_x_at BF689355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF689355 /FEA=EST /DB_XREF=gi:11974763 /DB_XREF=est:602184994T1 /CLONE=IMAGE:4299431 /UG=Hs.169476 glyceraldehyde-3-phosphate dehydrogenase BF689355 glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 213454_at AL578583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL578583 /FEA=EST /DB_XREF=gi:12942797 /DB_XREF=est:AL578583 /CLONE=CS0DK001YJ03 (3 prime) /UG=Hs.44205 cortistatin AL578583 apoptosis-inducing, TAF9-like domain 1 /// APITD1-CORT readthrough APITD1 /// APITD1-CORT 378708 /// 100526739 NM_001243768 /// NM_001270517 /// NM_198544 /// NM_199006 /// NM_199294 /// NR_036462 /// NR_037187 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay /// 0071821 // FANCM-MHF complex // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213455_at W87466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87466 /FEA=EST /DB_XREF=gi:1401521 /DB_XREF=est:zh67c05.s1 /CLONE=IMAGE:417128 /UG=Hs.246885 hypothetical protein FLJ20783 W87466 family with sequence similarity 114, member A1 FAM114A1 92689 NM_138389 /// NR_033290 /// XM_005262672 /// XM_005262673 /// XM_006714033 0005737 // cytoplasm // inferred from electronic annotation 213456_at AI927000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927000 /FEA=EST /DB_XREF=gi:5662964 /DB_XREF=est:wo68g02.x1 /CLONE=IMAGE:2460530 /UG=Hs.25956 DKFZP564D206 protein AI927000 sclerostin domain containing 1 SOSTDC1 25928 NM_015464 0007389 // pattern specification process // inferred from electronic annotation /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0060648 // mammary gland bud morphogenesis // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213457_at BF739959 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF739959 /FEA=EST /DB_XREF=gi:12066635 /DB_XREF=est:7o41e04.x1 /CLONE=IMAGE:3576678 /UG=Hs.24724 MFH-amplified sequences with leucine-rich tandem repeats 1 /FL=gb:AB016816.1 gb:NM_004225.1 BF739959 malignant fibrous histiocytoma amplified sequence 1 MFHAS1 9258 NM_004225 /// XR_246634 0005515 // protein binding // inferred from physical interaction 213458_at AB023191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023191.1 /DEF=Homo sapiens mRNA for KIAA0974 protein, partial cds. /FEA=mRNA /GEN=KIAA0974 /PROD=KIAA0974 protein /DB_XREF=gi:4589591 /UG=Hs.44131 KIAA0974 protein AB023191 family with sequence similarity 149, member B1 FAM149B1 317662 NM_173348 /// XM_005269744 /// XM_005269745 /// XM_005269746 /// XM_005269747 /// XM_006717815 213459_at AU155515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU155515 /FEA=EST /DB_XREF=gi:11017036 /DB_XREF=est:AU155515 /CLONE=PLACE1000061 /UG=Hs.296290 Homo sapiens cDNA FLJ13357 fis, clone PLACE1000061, weakly similar to Human ribosomal protein L37a mRNA sequence AU155515 ribosomal protein L37a RPL37A 6168 NM_000998 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213460_x_at N29665 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N29665 /FEA=EST /DB_XREF=gi:1148185 /DB_XREF=est:yw73e06.s1 /CLONE=IMAGE:257890 /UG=Hs.295112 KIAA0618 gene product N29665 NOP2/Sun domain family, member 5 pseudogene 1 /// NOP2/Sun domain family, member 5 pseudogene 2 NSUN5P1 /// NSUN5P2 155400 /// 260294 NM_001039487 /// NM_001039575 /// NM_001039576 /// NM_148936 /// NM_148980 /// NR_033322 /// NR_033323 /// NR_104013 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213461_at AI800983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI800983 /FEA=EST /DB_XREF=gi:5366455 /DB_XREF=est:wg15b02.x1 /CLONE=IMAGE:2365131 /UG=Hs.288061 actin, beta AI800983 nudix (nucleoside diphosphate linked moiety X)-type motif 21 NUDT21 11051 NM_007006 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213462_at AW000928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW000928 /FEA=EST /DB_XREF=gi:5847844 /DB_XREF=est:wr90e03.x1 /CLONE=IMAGE:2494972 /UG=Hs.296355 Homo sapiens cDNA: FLJ23138 fis, clone LNG08913 AW000928 neuronal PAS domain protein 2 NPAS2 4862 NM_002518 /// XM_005263953 /// XM_005263954 /// XM_005263955 /// XM_005263957 /// XM_005263958 /// XM_005263959 /// XM_005263960 /// XM_005263961 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from physical interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 213463_s_at AW300504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW300504 /FEA=EST /DB_XREF=gi:6710181 /DB_XREF=est:xs66c11.x1 /CLONE=IMAGE:2774612 /UG=Hs.44131 KIAA0974 protein AW300504 family with sequence similarity 149, member B1 FAM149B1 317662 NM_173348 /// XM_005269744 /// XM_005269745 /// XM_005269746 /// XM_005269747 /// XM_006717815 213464_at AV705938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705938 /FEA=EST /DB_XREF=gi:10723228 /DB_XREF=est:AV705938 /CLONE=ADBAIC03 /UG=Hs.30965 neuronal Shc adaptor homolog AV705938 SHC (Src homology 2 domain containing) transforming protein 2 SHC2 25759 NM_012435 /// XM_005259529 0007265 // Ras protein signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 213465_s_at BF718769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF718769 /FEA=EST /DB_XREF=gi:12019514 /DB_XREF=est:KEST72 /CLONE=S90413.NIH-107-R.ab1 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 BF718769 protein phosphatase 1, regulatory subunit 7 PPP1R7 5510 NM_001282409 /// NM_001282410 /// NM_001282411 /// NM_001282412 /// NM_001282413 /// NM_001282414 /// NM_002712 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 213466_at BE965869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965869 /FEA=EST /DB_XREF=gi:11770687 /DB_XREF=est:601659047R1 /CLONE=IMAGE:3895858 /UG=Hs.31408 RAR (RAS like GTPASE) BE965869 RAB40C, member RAS oncogene family RAB40C 57799 NM_001172663 /// NM_001172664 /// NM_001172665 /// NM_001172666 /// NM_021168 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation 213467_at BF511718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511718 /FEA=EST /DB_XREF=gi:11595016 /DB_XREF=est:UI-H-BI4-aom-f-07-0-UI.s1 /CLONE=IMAGE:3085572 /UG=Hs.99034 GTP-binding protein Rho7 /FL=gb:NM_005440.2 BF511718 Rho family GTPase 2 RND2 8153 NM_005440 /// XM_005257706 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048672 // positive regulation of collateral sprouting // inferred from electronic annotation 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 213468_at AI918117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI918117 /FEA=EST /DB_XREF=gi:5637972 /DB_XREF=est:tn06b07.x1 /CLONE=IMAGE:2166805 /UG=Hs.99987 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) AI918117 excision repair cross-complementation group 2 ERCC2 2068 NM_000400 /// NM_001130867 /// XM_005258639 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from genetic interaction /// 0006289 // nucleotide-excision repair // non-traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009650 // UV protection // inferred from genetic interaction /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0022405 // hair cycle process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0032289 // central nervous system myelin formation // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0033683 // nucleotide-excision repair, DNA incision // inferred from mutant phenotype /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035315 // hair cell differentiation // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048820 // hair follicle maturation // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 1901990 // regulation of mitotic cell cycle phase transition // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005675 // holo TFIIH complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0071817 // MMXD complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0043139 // 5'-3' DNA helicase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 213469_at AV705244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705244 /FEA=EST /DB_XREF=gi:10722550 /DB_XREF=est:AV705244 /CLONE=ADBAHF09 /UG=Hs.25159 Homo sapiens cDNA FLJ10784 fis, clone NT2RP4000448, highly similar to Homo sapiens mRNA; cDNA DKFZp566G0746 AV705244 post-GPI attachment to proteins 1 PGAP1 80055 NM_024989 /// XM_005246866 /// XR_427112 0006501 // C-terminal protein lipidation // traceable author statement /// 0006505 // GPI anchor metabolic process // inferred from electronic annotation /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015798 // myo-inositol transport // inferred from sequence or structural similarity /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0021871 // forebrain regionalization // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0060322 // head development // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004518 // nuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from sequence or structural similarity 213470_s_at BF983406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF983406 /FEA=EST /DB_XREF=gi:12386218 /DB_XREF=est:602307011F1 /CLONE=IMAGE:4398315 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) BF983406 heterogeneous nuclear ribonucleoprotein H1 (H) HNRNPH1 3187 NM_001257293 /// NM_005520 /// XM_005265895 /// XM_005265896 /// XM_005265901 /// XM_005265902 /// XM_005265903 /// XM_006714862 /// XM_006714863 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 213471_at AB014573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014573.1 /DEF=Homo sapiens mRNA for KIAA0673 protein, partial cds. /FEA=mRNA /GEN=KIAA0673 /PROD=KIAA0673 protein /DB_XREF=gi:3327159 /UG=Hs.106487 KIAA0673 protein AB014573 nephronophthisis 4 NPHP4 261734 NM_001291593 /// NM_001291594 /// NM_015102 /// NR_111987 /// XM_006710563 /// XM_006710564 /// XM_006710565 /// XM_006710566 /// XM_006710567 /// XM_006710568 /// XM_006710569 /// XM_006710570 /// XR_244787 /// XR_426599 /// XR_426600 /// XR_426601 0007165 // signal transduction // non-traceable author statement /// 0007632 // visual behavior // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213472_at AI022387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI022387 /FEA=EST /DB_XREF=gi:3237628 /DB_XREF=est:ow72f02.x1 /CLONE=IMAGE:1652379 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) AI022387 heterogeneous nuclear ribonucleoprotein H1 (H) HNRNPH1 3187 NM_001257293 /// NM_005520 /// XM_005265895 /// XM_005265896 /// XM_005265901 /// XM_005265902 /// XM_005265903 /// XM_006714862 /// XM_006714863 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 213473_at AL042733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL042733 /FEA=EST /DB_XREF=gi:5935548 /DB_XREF=est:DKFZp434B2222_s1 /CLONE=DKFZp434B2222 /UG=Hs.122764 BRCA1 associated protein AL042733 BRCA1 associated protein BRAP 8315 NM_006768 /// XM_005253944 0000165 // MAPK cascade // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213474_at AI890903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI890903 /FEA=EST /DB_XREF=gi:5596067 /DB_XREF=est:wm91f10.x1 /CLONE=IMAGE:2443339 /UG=Hs.119683 ESTs AI890903 potassium channel tetramerization domain containing 7 /// RAB guanine nucleotide exchange factor (GEF) 1 KCTD7 /// RABGEF1 27342 /// 154881 NM_001167961 /// NM_001287060 /// NM_001287061 /// NM_001287062 /// NM_014504 /// NM_153033 /// NR_104676 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213475_s_at AC002310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002310 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-635H12 /FEA=mRNA_2 /DB_XREF=gi:2576342 /UG=Hs.174103 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) AC002310 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) ITGAL 3683 NM_001114380 /// NM_002209 /// XM_005255313 /// XM_006721044 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from mutant phenotype /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0001772 // immunological synapse // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 213476_x_at AL565749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565749 /FEA=EST /DB_XREF=gi:12917434 /DB_XREF=est:AL565749 /CLONE=CS0DF007YJ03 (3 prime) /UG=Hs.159154 tubulin, beta, 4 AL565749 tubulin, beta 3 class III TUBB3 10381 NM_001197181 /// NM_006086 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 213477_x_at AL515273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515273 /FEA=EST /DB_XREF=gi:12778766 /DB_XREF=est:AL515273 /CLONE=CL0BB016ZE08 (3 prime) /UG=Hs.284136 PRO2047 protein AL515273 eukaryotic translation elongation factor 1 alpha 1 EEF1A1 1915 NM_001402 /// NM_001403 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213478_at AB028949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028949.1 /DEF=Homo sapiens mRNA for KIAA1026 protein, partial cds. /FEA=mRNA /GEN=KIAA1026 /PROD=KIAA1026 protein /DB_XREF=gi:5689388 /UG=Hs.27742 KIAA1026 protein AB028949 kazrin, periplakin interacting protein KAZN 23254 NM_001017999 /// NM_001018000 /// NM_001018001 /// NM_015209 /// NM_201628 /// XM_005245795 /// XM_005245796 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 213479_at U26662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U26662.1 /DEF=Human neuronal pentraxin II (NPTX2) mRNA, partial cds. /FEA=mRNA /GEN=NPTX2 /PROD=neuronal pentraxin II /DB_XREF=gi:881933 /UG=Hs.3281 neuronal pentraxin II U26662 neuronal pentraxin II NPTX2 4885 NM_002523 0007268 // synaptic transmission // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 213480_at AF052100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052100.1 /DEF=Homo sapiens clone 23645 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360407 /UG=Hs.6651 Homo sapiens clone 23645 mRNA sequence AF052100 vesicle-associated membrane protein 4 VAMP4 8674 NM_001185127 /// NM_003762 /// NM_201994 /// NR_033704 /// XR_426805 0006887 // exocytosis // not recorded /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035493 // SNARE complex assembly // inferred from direct assay /// 0042996 // regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded 213481_at N92920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92920 /FEA=EST /DB_XREF=gi:1265229 /DB_XREF=est:zb57c08.s1 /CLONE=IMAGE:307694 /UG=Hs.323817 DKFZP547E1010 protein N92920 S100 calcium binding protein A13 S100A13 6284 NM_001024210 /// NM_001024211 /// NM_001024212 /// NM_001024213 /// NM_005979 /// XM_005245434 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043303 // mast cell degranulation // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from mutant phenotype /// 0050703 // interleukin-1 alpha secretion // inferred from direct assay /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0042629 // mast cell granule // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 213482_at BF593175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593175 /FEA=EST /DB_XREF=gi:11685499 /DB_XREF=est:7o57g10.x1 /CLONE=IMAGE:3578322 /UG=Hs.7022 dedicator of cyto-kinesis 3 BF593175 dedicator of cytokinesis 3 DOCK3 1795 NM_004947 /// XM_005264914 /// XM_005264915 /// XM_005264916 /// XM_005264917 /// XM_005264918 /// XM_006713008 /// XM_006713009 /// XM_006713010 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 213483_at AK025679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025679.1 /DEF=Homo sapiens cDNA: FLJ22026 fis, clone HEP08537. /FEA=mRNA /DB_XREF=gi:10438273 /UG=Hs.1191 KIAA0073 protein AK025679 peptidylprolyl isomerase domain and WD repeat containing 1 PPWD1 23398 NM_001278926 /// NM_001278927 /// NM_001278929 /// NM_015342 /// XM_005248474 /// XM_005248475 /// XM_006714582 /// XM_006714583 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 213484_at AI097640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI097640 /FEA=EST /DB_XREF=gi:3445898 /DB_XREF=est:qb59a08.x1 /CLONE=IMAGE:1704374 /UG=Hs.66187 Homo sapiens clone 23700 mRNA sequence AI097640 adducin 2 (beta) ADD2 119 NM_001185054 /// NM_001185055 /// NM_001617 /// NM_017482 /// NM_017483 /// NM_017484 /// NM_017485 /// NM_017486 /// NM_017487 /// NM_017488 0006461 // protein complex assembly // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 213485_s_at AK000002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000002.1 /DEF=Homo sapiens mRNA for FLJ00002 protein, partial cds. /FEA=mRNA /GEN=FLJ00002 /PROD=FLJ00002 protein /DB_XREF=gi:7209304 /UG=Hs.55879 hypothetical protein MGC2487 AK000002 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 ABCC10 89845 NM_001198934 /// NM_033450 /// XM_005249470 /// XM_006715240 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 213486_at BF435376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF435376 /FEA=EST /DB_XREF=gi:11447664 /DB_XREF=est:nab38h02.x1 /CLONE=IMAGE:3268442 /UG=Hs.6421 hypothetical protein DKFZp761N09121 BF435376 COPG2 imprinted transcript 1 (non-protein coding) COPG2IT1 53844 NR_024086 213487_at AI762811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762811 /FEA=EST /DB_XREF=gi:5178478 /DB_XREF=est:wi04d12.x1 /CLONE=IMAGE:2389271 /UG=Hs.72241 mitogen-activated protein kinase kinase 2 AI762811 mitogen-activated protein kinase kinase 2 MAP2K2 5605 NM_030662 /// XM_006722799 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036289 // peptidyl-serine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000147 // positive regulation of cell motility // inferred from electronic annotation /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 213488_at N73970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N73970 /FEA=EST /DB_XREF=gi:1231255 /DB_XREF=est:za74h03.s1 /CLONE=IMAGE:298325 /UG=Hs.7949 DKFZP586B2420 protein N73970 sushi, nidogen and EGF-like domains 1 SNED1 25992 NM_001080437 /// XM_005246997 /// XM_006712405 /// XM_006712406 /// XM_006712407 /// XR_427081 /// XR_427082 /// XR_427083 /// XR_427084 0007160 // cell-matrix adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213489_at BE671156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE671156 /FEA=EST /DB_XREF=gi:10031697 /DB_XREF=est:7e46f09.x1 /CLONE=IMAGE:3285545 /UG=Hs.78335 microtubule-associated protein, RPEB family, member 2 BE671156 microtubule-associated protein, RP/EB family, member 2 MAPRE2 10982 NM_001143826 /// NM_001143827 /// NM_001256420 /// NM_014268 /// NR_046177 /// XM_006722375 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 213490_s_at AI762811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762811 /FEA=EST /DB_XREF=gi:5178478 /DB_XREF=est:wi04d12.x1 /CLONE=IMAGE:2389271 /UG=Hs.72241 mitogen-activated protein kinase kinase 2 AI762811 mitogen-activated protein kinase kinase 2 MAP2K2 5605 NM_030662 /// XM_006722799 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036289 // peptidyl-serine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000147 // positive regulation of cell motility // inferred from electronic annotation /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 213491_x_at AL514285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL514285 /FEA=EST /DB_XREF=gi:12777779 /DB_XREF=est:AL514285 /CLONE=CL0BB007ZF04 (3 prime) /UG=Hs.75722 ribophorin II AL514285 ribophorin II RPN2 6185 NM_001135771 /// NM_002951 /// XM_005260491 /// XM_006723849 /// XM_006723850 /// XM_006723851 /// XM_006723852 0006412 // translation // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // non-traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation 213492_at X06268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06268.1 /DEF=Human mRNA for pro-alpha 1 (II) collagen 3end C-term. triple helical and C-terminal non-helical domain. /FEA=mRNA /PROD=pro-alpha 1 (II) collagen (313 AA; AA 975-271c) /DB_XREF=gi:30096 /UG=Hs.81343 collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) /FL=gb:NM_001844.2 X06268 collagen, type II, alpha 1 COL2A1 1280 NM_001844 /// NM_033150 /// XM_006719242 0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0030903 // notochord development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051216 // cartilage development // traceable author statement /// 0060021 // palate development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005585 // collagen type II trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030020 // extracellular matrix structural constituent conferring tensile strength // inferred by curator /// 0042802 // identical protein binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 213493_at BF509657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF509657 /FEA=EST /DB_XREF=gi:11592955 /DB_XREF=est:UI-H-BI4-apb-b-10-0-UI.s1 /CLONE=IMAGE:3086563 /UG=Hs.7949 DKFZP586B2420 protein BF509657 sushi, nidogen and EGF-like domains 1 SNED1 25992 NM_001080437 /// XM_005246997 /// XM_006712405 /// XM_006712406 /// XM_006712407 /// XR_427081 /// XR_427082 /// XR_427083 /// XR_427084 0007160 // cell-matrix adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213494_s_at AA748649 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA748649 /FEA=EST /DB_XREF=gi:2788607 /DB_XREF=est:ny10b11.s1 /CLONE=IMAGE:1271325 /UG=Hs.97496 YY1 transcription factor AA748649 YY1 transcription factor YY1 7528 NM_003403 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213495_s_at AW166067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW166067 /FEA=EST /DB_XREF=gi:6397592 /DB_XREF=est:xf44g10.x1 /CLONE=IMAGE:2620962 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) AW166067 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 213496_at AW592563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW592563 /FEA=EST /DB_XREF=gi:7279747 /DB_XREF=est:hf44d09.x1 /CLONE=IMAGE:2934737 /UG=Hs.13245 KIAA0455 gene product AW592563 lipid phosphate phosphatase-related protein type 4 LPPR4 9890 NM_001166252 /// NM_014839 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0046839 // phospholipid dephosphorylation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from electronic annotation 213497_at AL050374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050374.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C1619 (from clone DKFZp586C1619). /FEA=mRNA /DB_XREF=gi:4914579 /UG=Hs.108169 Homo sapiens mRNA; cDNA DKFZp586C1619 (from clone DKFZp586C1619) AL050374 ankyrin repeat and BTB (POZ) domain containing 2 ABTB2 25841 NM_145804 0001558 // regulation of cell growth // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213498_at BG328407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG328407 /FEA=EST /DB_XREF=gi:13134845 /DB_XREF=est:602427745F1 /CLONE=IMAGE:4547050 /UG=Hs.13456 Homo sapiens clone 24747 mRNA sequence BG328407 cAMP responsive element binding protein 3-like 1 CREB3L1 90993 NM_052854 /// XM_006718380 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213499_at NM_004366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004366.2 /DEF=Homo sapiens chloride channel 2 (CLCN2), mRNA. /FEA=CDS /GEN=CLCN2 /PROD=chloride channel 2 /DB_XREF=gi:5803001 /UG=Hs.141660 chloride channel 2 /FL=gb:AF026004.1 gb:NM_004366.2 NM_004366 chloride channel, voltage-sensitive 2 CLCN2 1181 NM_001171087 /// NM_001171088 /// NM_001171089 /// NM_004366 /// XM_006713488 /// XM_006713489 /// XM_006713490 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060689 // cell differentiation involved in salivary gland development // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 213500_at AI307760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI307760 /FEA=EST /DB_XREF=gi:4002364 /DB_XREF=est:tb24g09.x1 /CLONE=IMAGE:2055328 /UG=Hs.14074 Homo sapiens clone 24627 mRNA sequence AI307760 213501_at T62985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T62985 /FEA=EST /DB_XREF=gi:666642 /DB_XREF=est:yc15d05.s1 /CLONE=IMAGE:80745 /UG=Hs.167835 acyl-Coenzyme A oxidase 1, palmitoyl T62985 acyl-CoA oxidase 1, palmitoyl ACOX1 51 NM_001185039 /// NM_004035 /// NM_007292 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from genetic interaction /// 0019395 // fatty acid oxidation // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from mutant phenotype /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from genetic interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2000189 // positive regulation of cholesterol homeostasis // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from direct assay /// 0003997 // acyl-CoA oxidase activity // inferred from genetic interaction /// 0003997 // acyl-CoA oxidase activity // inferred from mutant phenotype /// 0003997 // acyl-CoA oxidase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0016401 // palmitoyl-CoA oxidase activity // inferred from direct assay /// 0016401 // palmitoyl-CoA oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 213502_x_at AA398569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA398569 /FEA=EST /DB_XREF=gi:2051678 /DB_XREF=est:zt73g04.s1 /CLONE=IMAGE:728022 /UG=Hs.296552 immunoglobulin lambda-like polypeptide 3 AA398569 glucuronidase, beta pseudogene 11 GUSBP11 91316 NR_024448 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 213503_x_at BE908217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE908217 /FEA=EST /DB_XREF=gi:10402569 /DB_XREF=est:601500477F1 /CLONE=IMAGE:3902323 /UG=Hs.217493 annexin A2 BE908217 annexin A2 ANXA2 302 NM_001002857 /// NM_001002858 /// NM_001136015 /// NM_004039 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 213504_at W63732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W63732 /FEA=EST /DB_XREF=gi:1371312 /DB_XREF=est:zd30b06.s1 /CLONE=IMAGE:342131 /UG=Hs.15591 COP9 subunit 6 (MOV34 homolog, 34 kD) W63732 COP9 signalosome subunit 6 COPS6 10980 NM_006833 0010388 // cullin deneddylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213505_s_at BG252853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG252853 /FEA=EST /DB_XREF=gi:12762669 /DB_XREF=est:602365438F1 /CLONE=IMAGE:4473753 /UG=Hs.190452 KIAA0365 gene product BG252853 SURP and G patch domain containing 2 SUGP2 10147 NM_001017392 /// NM_014884 /// XR_430120 /// XR_430121 /// XR_430122 /// XR_430123 /// XR_430124 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213506_at BE965369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965369 /FEA=EST /DB_XREF=gi:11769659 /DB_XREF=est:601659282R1 /CLONE=IMAGE:3895653 /UG=Hs.168102 Human proteinase activated receptor-2 mRNA, 3UTR BE965369 coagulation factor II (thrombin) receptor-like 1 F2RL1 2150 NM_005242 0002286 // T cell activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0002741 // positive regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // inferred from electronic annotation /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from sequence or structural similarity /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0034137 // positive regulation of toll-like receptor 2 signaling pathway // inferred from mutant phenotype /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0034141 // positive regulation of toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0035926 // chemokine (C-C motif) ligand 2 secretion // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043311 // positive regulation of eosinophil degranulation // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050702 // interleukin-1 beta secretion // inferred from direct assay /// 0050900 // leukocyte migration // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation /// 0070661 // leukocyte proliferation // inferred from sequence or structural similarity /// 0070963 // positive regulation of neutrophil mediated killing of gram-negative bacterium // inferred from direct assay /// 0072608 // interleukin-10 secretion // inferred from direct assay /// 0072643 // interferon-gamma secretion // inferred from sequence or structural similarity /// 0090195 // chemokine secretion // inferred from direct assay /// 0090198 // negative regulation of chemokine secretion // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from direct assay /// 0097029 // mature dendritic cell differentiation // inferred from sequence or structural similarity /// 1900135 // positive regulation of renin secretion into blood stream // inferred from sequence or structural similarity /// 2000484 // positive regulation of interleukin-8 secretion // inferred from direct assay /// 2000778 // positive regulation of interleukin-6 secretion // inferred from direct assay 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from sequence or structural similarity 0001965 // G-protein alpha-subunit binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // inferred from electronic annotation /// 0031681 // G-protein beta-subunit binding // inferred from sequence or structural similarity 213507_s_at BG249565 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG249565 /FEA=EST /DB_XREF=gi:12759381 /DB_XREF=est:602319636F1 /CLONE=IMAGE:4414881 /UG=Hs.180446 karyopherin (importin) beta 1 BG249565 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213508_at AA142942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA142942 /FEA=EST /DB_XREF=gi:1712320 /DB_XREF=est:zl43c04.s1 /CLONE=IMAGE:504678 /UG=Hs.241507 ribosomal protein S6 AA142942 serine palmitoyltransferase, small subunit A SPTSSA 171546 NM_138288 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213509_x_at AW157619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157619 /FEA=EST /DB_XREF=gi:6229020 /DB_XREF=est:au85a11.x1 /CLONE=IMAGE:2783036 /UG=Hs.282975 carboxylesterase 2 (intestine, liver) AW157619 carboxylesterase 2 CES2 8824 NM_003869 /// NM_198061 /// NR_036684 0008152 // metabolic process // inferred from electronic annotation /// 0009056 // catabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // traceable author statement 213510_x_at AW194543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194543 /FEA=EST /DB_XREF=gi:6473381 /DB_XREF=est:xb27c02.x1 /CLONE=IMAGE:2577506 /UG=Hs.234573 Homo sapiens mRNA for TL132 AW194543 ubiquitin specific peptidase 32 pseudogene 2 USP32P2 220594 NM_145809 /// NR_003554 213511_s_at AI167164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI167164 /FEA=EST /DB_XREF=gi:3700334 /DB_XREF=est:oo08c10.x1 /CLONE=IMAGE:1565586 /UG=Hs.23200 myotubularin related protein 1 AI167164 myotubularin related protein 1 MTMR1 8776 NM_003828 /// NM_176789 /// XM_005274765 /// XM_005274766 /// XM_005274767 /// XM_005274768 /// XM_006724854 /// XM_006724855 /// XM_006724856 /// XR_247319 /// XR_430557 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from sequence or structural similarity /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 213512_at BF109941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF109941 /FEA=EST /DB_XREF=gi:10939631 /DB_XREF=est:7l72c05.x1 /CLONE=IMAGE:3527024 /UG=Hs.27183 Homo sapiens clone 23940 mRNA sequence BF109941 chromosome 14 open reading frame 79 C14orf79 122616 NM_174891 /// XM_005267317 /// XM_005267318 213513_x_at BG034239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG034239 /FEA=EST /DB_XREF=gi:12427339 /DB_XREF=est:602302301F1 /CLONE=IMAGE:4403617 /UG=Hs.252280 Rho guanine nucleotide exchange factor (GEF) 1 BG034239 actin related protein 2/3 complex, subunit 2, 34kDa ARPC2 10109 NM_005731 /// NM_152862 /// XM_006712173 0006928 // cellular component movement // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from electronic annotation /// 0035650 // AP-1 adaptor complex binding // inferred from electronic annotation /// 0071933 // Arp2/3 complex binding // inferred from electronic annotation 213514_s_at AU158818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158818 /FEA=EST /DB_XREF=gi:11020339 /DB_XREF=est:AU158818 /CLONE=THYRO1000147 /UG=Hs.26584 diaphanous (Drosophila, homolog) 1 AU158818 diaphanous-related formin 1 DIAPH1 1729 NM_001079812 /// NM_005219 /// XM_005268384 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071420 // cellular response to histamine // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213515_x_at AI133353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI133353 /FEA=EST /DB_XREF=gi:6360669 /DB_XREF=est:HA1957 /UG=Hs.298161 myosin, light polypeptide 4, alkali; atrial, embryonic AI133353 hemoglobin, gamma A /// hemoglobin, gamma G HBG1 /// HBG2 3047 /// 3048 NM_000184 /// NM_000559 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213516_at AF126008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF126008.1 /DEF=Homo sapiens breast cancer nuclear receptor-binding auxiliary protein (BRX) mRNA, complete cds. /FEA=CDS /GEN=BRX /PROD=breast cancer nuclear receptor-binding auxiliaryprotein /DB_XREF=gi:4469557 /UG=Hs.301946 lymphoid blast crisis oncogene /FL=gb:AF126008.1 AF126008 213517_at AW103422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW103422 /FEA=EST /DB_XREF=gi:6074157 /DB_XREF=est:xd36a02.x1 /CLONE=IMAGE:2595818 /UG=Hs.63525 poly(rC)-binding protein 2 AW103422 poly(rC) binding protein 2 PCBP2 5094 NM_001098620 /// NM_001128911 /// NM_001128912 /// NM_001128913 /// NM_001128914 /// NM_005016 /// NM_031989 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213518_at AI689429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI689429 /FEA=EST /DB_XREF=gi:4900723 /DB_XREF=est:tx83h10.x1 /CLONE=IMAGE:2276227 /UG=Hs.47144 DKFZP586N0819 protein AI689429 protein kinase C, iota PRKCI 5584 NM_002740 0006468 // protein phosphorylation // inferred from direct assay /// 0006612 // protein targeting to membrane // non-traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035089 // establishment of apical/basal cell polarity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // traceable author statement /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046903 // secretion // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048194 // Golgi vesicle budding // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0060252 // positive regulation of glial cell proliferation // inferred from mutant phenotype /// 0061024 // membrane organization // non-traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0000133 // polarisome // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005543 // phospholipid binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213519_s_at AI078169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI078169 /FEA=EST /DB_XREF=gi:3412577 /DB_XREF=est:oz30d11.x1 /CLONE=IMAGE:1676853 /UG=Hs.323511 Homo sapiens cDNA: FLJ23176 fis, clone LNG10452 AI078169 laminin, alpha 2 LAMA2 3908 NM_000426 /// NM_001079823 /// XM_005266981 /// XM_005266982 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 213520_at NM_004260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004260.1 /DEF=Homo sapiens RecQ protein-like 4 (RECQL4), mRNA. /FEA=CDS /GEN=RECQL4 /PROD=RecQ protein-like 4 /DB_XREF=gi:4759029 /UG=Hs.31442 RecQ protein-like 4 /FL=gb:AB006532.1 gb:NM_004260.1 NM_004260 RecQ protein-like 4 RECQL4 9401 NM_004260 0000733 // DNA strand renaturation // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0043473 // pigmentation // inferred from electronic annotation /// 0045875 // negative regulation of sister chromatid cohesion // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000405 // bubble DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0043140 // ATP-dependent 3'-5' DNA helicase activity // inferred from mutant phenotype 213521_at AW575379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW575379 /FEA=EST /DB_XREF=gi:7246918 /DB_XREF=est:UI-HF-BL0-adc-e-05-0-UI.s1 /CLONE=IMAGE:3060969 /UG=Hs.6551 ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 AW575379 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) PTPN18 26469 NM_001142370 /// NM_014369 /// XM_006712415 /// XM_006712416 /// XM_006712417 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 213522_s_at AA527578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA527578 /FEA=EST /DB_XREF=gi:2269647 /DB_XREF=est:ng42c08.s1 /CLONE=IMAGE:937454 /UG=Hs.85838 solute carrier family 16 (monocarboxylic acid transporters), member 3 AA527578 casein kinase 1, delta CSNK1D 1453 NM_001893 /// NM_139062 /// NR_110578 /// XM_005256336 /// XM_005256337 /// XR_243518 /// XR_430027 /// XR_430028 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 213523_at AI671049 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI671049 /FEA=EST /DB_XREF=gi:4850780 /DB_XREF=est:tz17d11.x1 /CLONE=IMAGE:2288853 /UG=Hs.9700 cyclin E1 AI671049 cyclin E1 CCNE1 898 NM_001238 /// NM_057182 /// XM_005259370 /// XM_006723457 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // non-traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 213524_s_at NM_015714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_015714.1 /DEF=Homo sapiens putative lymphocyte G0G1 switch gene (G0S2), mRNA. /FEA=CDS /GEN=G0S2 /PROD=putative lymphocyte G0G1 switch gene /DB_XREF=gi:7657103 /UG=Hs.95910 putative lymphocyte G0G1 switch gene /FL=gb:NM_015714.1 NM_015714 G0/G1 switch 2 G0S2 50486 NM_015714 0006915 // apoptotic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // traceable author statement 0005515 // protein binding // inferred from physical interaction 213525_at AC002310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002310 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-635H12 /FEA=CDS_1 /DB_XREF=gi:2576342 /UG=Hs.301463 Human Chromosome 16 BAC clone CIT987SK-A-635H12 AC002310 /// Homo sapiens cDNA clone IMAGE:4906981, partial cds. AC002310.7 /// ZNF785 213526_s_at BF215644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF215644 /FEA=EST /DB_XREF=gi:11109230 /DB_XREF=est:601881119F1 /CLONE=IMAGE:4093444 /UG=Hs.42514 hypothetical protein F25965 BF215644 lin-37 homolog (C. elegans) LIN37 55957 NM_019104 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213527_s_at AI095896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI095896 /FEA=EST /DB_XREF=gi:3434872 /DB_XREF=est:qb21a10.x1 /CLONE=IMAGE:1696890 /UG=Hs.301463 Human Chromosome 16 BAC clone CIT987SK-A-635H12 AI095896 zinc finger protein 688 ZNF688 146542 NM_001024683 /// NM_145271 /// XM_005255138 /// XM_005255139 /// XM_005255140 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213528_at AL035369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035369.1 /DEF=H.sapiens novel gene from PAC 117P20, chromosome 1. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4239681 /UG=Hs.33922 H.sapiens novel gene from PAC 117P20, chromosome 1 AL035369 methyltransferase like 18 METTL18 92342 NM_033418 /// XM_005245606 /// XM_006711627 0006479 // protein methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213529_at AI350500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI350500 /FEA=EST /DB_XREF=gi:4087706 /DB_XREF=est:qt17h03.x1 /CLONE=IMAGE:1947893 /UG=Hs.301463 Human Chromosome 16 BAC clone CIT987SK-A-635H12 AI350500 zinc finger protein 688 ZNF688 146542 NM_001024683 /// NM_145271 /// XM_005255138 /// XM_005255139 /// XM_005255140 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213530_at AI040009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040009 /FEA=EST /DB_XREF=gi:3279203 /DB_XREF=est:ox97e08.x1 /CLONE=IMAGE:1664294 /UG=Hs.309509 Human mRNA related to a calmodulin-like, processed pseudogene (302 bp identical to the 3 untranslated region) AI040009 RAB3 GTPase activating protein subunit 1 (catalytic) RAB3GAP1 22930 NM_001172435 /// NM_012233 /// XR_427077 /// XR_427078 0007420 // brain development // inferred from mutant phenotype /// 0021854 // hypothalamus development // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 213531_s_at AI040009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040009 /FEA=EST /DB_XREF=gi:3279203 /DB_XREF=est:ox97e08.x1 /CLONE=IMAGE:1664294 /UG=Hs.309509 Human mRNA related to a calmodulin-like, processed pseudogene (302 bp identical to the 3 untranslated region) AI040009 RAB3 GTPase activating protein subunit 1 (catalytic) RAB3GAP1 22930 NM_001172435 /// NM_012233 /// XR_427077 /// XR_427078 0007420 // brain development // inferred from mutant phenotype /// 0021854 // hypothalamus development // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 213532_at AI797833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI797833 /FEA=EST /DB_XREF=gi:5363390 /DB_XREF=est:wh79e10.x1 /CLONE=IMAGE:2386986 /UG=Hs.52438 ESTs, Weakly similar to ORF YOR126c S.cerevisiae AI797833 ADAM metallopeptidase domain 17 ADAM17 6868 NM_003183 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002467 // germinal center formation // inferred from sequence or structural similarity /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0006508 // proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from mutant phenotype /// 0032722 // positive regulation of chemokine production // inferred from mutant phenotype /// 0033025 // regulation of mast cell apoptotic process // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033627 // cell adhesion mediated by integrin // inferred from direct assay /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0035625 // epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from sequence or structural similarity /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from direct assay /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055099 // response to high density lipoprotein particle // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // traceable author statement /// 0005112 // Notch binding // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213533_at M98528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M98528 /DEF=Homo sapiens neuron-specific protein gene, last exon, clone D4S234 /FEA=mRNA /DB_XREF=gi:190258 /UG=Hs.79404 neuron-specific protein M98528 neuron specific gene family member 1 NSG1 27065 NM_001040101 /// NM_001287763 /// NM_001287764 /// NM_014392 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0032051 // clathrin light chain binding // inferred from electronic annotation 213534_s_at D50925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D50925.1 /DEF=Human mRNA for KIAA0135 gene, partial cds. /FEA=mRNA /GEN=KIAA0135 /DB_XREF=gi:1469192 /UG=Hs.79337 KIAA0135 protein D50925 PAS domain containing serine/threonine kinase PASK 23178 NM_001252119 /// NM_001252120 /// NM_001252122 /// NM_001252124 /// NM_015148 /// XM_005246990 /// XM_005246991 /// XR_427079 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045727 // positive regulation of translation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0070092 // regulation of glucagon secretion // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 213535_s_at AA910614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA910614 /FEA=EST /DB_XREF=gi:3049904 /DB_XREF=est:ok61b04.s1 /CLONE=IMAGE:1518415 /UG=Hs.84285 ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) AA910614 ubiquitin-conjugating enzyme E2I UBE2I 7329 NM_003345 /// NM_194259 /// NM_194260 /// NM_194261 /// XM_005255540 /// XM_005255541 /// XM_006720938 /// XM_006720939 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033145 // positive regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // traceable author statement /// 0001650 // fibrillar center // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0043398 // HLH domain binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 213536_s_at AA910614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA910614 /FEA=EST /DB_XREF=gi:3049904 /DB_XREF=est:ok61b04.s1 /CLONE=IMAGE:1518415 /UG=Hs.84285 ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) AA910614 LA16c-358B7.3 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0033145 // positive regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // traceable author statement /// 0001650 // fibrillar center // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043398 // HLH domain binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 213537_at AI128225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI128225 /FEA=EST /DB_XREF=gi:3596739 /DB_XREF=est:qc33e05.x1 /CLONE=IMAGE:1711424 /UG=Hs.914 Human mRNA for SB classII histocompatibility antigen alpha-chain AI128225 major histocompatibility complex, class II, DP alpha 1 HLA-DPA1 3113 NM_001242524 /// NM_001242525 /// NM_033554 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 213538_at AI936458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI936458 /FEA=EST /DB_XREF=gi:5675328 /DB_XREF=est:wd28b10.x1 /CLONE=IMAGE:2329435 /UG=Hs.92909 SON DNA binding protein AI936458 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 213539_at NM_000732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000732.1 /DEF=Homo sapiens CD3D antigen, delta polypeptide (TiT3 complex) (CD3D), mRNA. /FEA=CDS /GEN=CD3D /PROD=CD3D antigen, delta polypeptide (TiT3 complex) /DB_XREF=gi:4502668 /UG=Hs.95327 CD3D antigen, delta polypeptide (TiT3 complex) /FL=gb:NM_000732.1 NM_000732 CD3d molecule, delta (CD3-TCR complex) CD3D 915 NM_000732 /// NM_001040651 0007166 // cell surface receptor signaling pathway // inferred by curator /// 0030217 // T cell differentiation // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay /// 0042101 // T cell receptor complex // non-traceable author statement /// 0042105 // alpha-beta T cell receptor complex // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred by curator /// 0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 213540_at AL031228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031228 /DEF=Human DNA sequence from clone 1033B10 on chromosome 6p21.2-21.31. Contains the BING5 gene, exons 11 to 15 of the BING4 gene, the gene for GalT3 (beta3-Galactosyltransferase), the RPS18 (40S ribosomal protein S18) gene, the SACM2L (suppressor of ac... /FEA=mRNA_1 /DB_XREF=gi:3646023 /UG=Hs.288354 FabG (beta-ketoacyl-acyl-carrier-protein reductase, E coli) like AL031228 hydroxysteroid (17-beta) dehydrogenase 8 HSD17B8 7923 NM_014234 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // inferred from direct assay /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from direct assay /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation 213541_s_at AI351043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI351043 /FEA=EST /DB_XREF=gi:4088249 /DB_XREF=est:qt22a08.x1 /CLONE=IMAGE:1948310 /UG=Hs.279477 ESTs AI351043 v-ets avian erythroblastosis virus E26 oncogene homolog ERG 2078 NM_001136154 /// NM_001136155 /// NM_001243428 /// NM_001243429 /// NM_001243432 /// NM_001243433 /// NM_001291391 /// NM_004449 /// NM_182918 /// NR_111949 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213542_at AI246730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI246730 /FEA=EST /DB_XREF=gi:3842127 /DB_XREF=est:qk40b01.x1 /CLONE=IMAGE:1871401 /UG=Hs.126901 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 375854 AI246730 zinc finger protein 710 ZNF710 374655 NM_198526 /// XM_005254905 /// XM_005254906 /// XM_005254907 /// XM_006720498 /// XM_006720499 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213543_at AA570453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA570453 /FEA=EST /DB_XREF=gi:2344433 /DB_XREF=est:nk62f11.s1 /CLONE=IMAGE:1018125 /UG=Hs.10323 Homo sapiens mRNA from chromosome 5q31-33 region AA570453 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) SGCD 6444 NM_000337 /// NM_001128209 /// NM_172244 /// XM_005265965 /// XM_005265966 /// XM_005265967 /// XM_006714911 /// XM_006714912 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 213544_at AI186701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186701 /FEA=EST /DB_XREF=gi:3737339 /DB_XREF=est:qe82d12.x1 /CLONE=IMAGE:1745495 /UG=Hs.107153 inhibitor of growth family, member 1-like AI186701 inhibitor of growth family, member 2 ING2 3622 NM_001291959 /// NM_001564 /// XM_005262982 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007141 // male meiosis I // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from sequence or structural similarity /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048133 // male germ-line stem cell division // inferred from sequence or structural similarity /// 0072520 // seminiferous tubule development // inferred from sequence or structural similarity /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // traceable author statement /// 2000772 // regulation of cellular senescence // non-traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 213545_x_at BE962615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962615 /FEA=EST /DB_XREF=gi:11765691 /DB_XREF=est:601655968R1 /CLONE=IMAGE:3855785 /UG=Hs.12102 sorting nexin 3 BE962615 sorting nexin 3 SNX3 8724 NM_003795 /// NM_152827 /// NM_152828 /// XM_005267192 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 213546_at AL050378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050378.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I1420 (from clone DKFZp586I1420); partial cds. /FEA=mRNA /GEN=DKFZp586I1420 /PROD=hypothetical protein /DB_XREF=gi:4914581 /UG=Hs.112423 Homo sapiens mRNA; cDNA DKFZp586I1420 (from clone DKFZp586I1420); partial cds AL050378 uncharacterized protein DKFZp586I1420 DKFZP586I1420 222161 NR_002186 213547_at AB014567 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014567.1 /DEF=Homo sapiens mRNA for KIAA0667 protein, partial cds. /FEA=mRNA /GEN=KIAA0667 /PROD=KIAA0667 protein /DB_XREF=gi:3327147 /UG=Hs.154740 TBP-interacting protein AB014567 cullin-associated and neddylation-dissociated 2 (putative) CAND2 23066 NM_001162499 /// NM_012298 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from electronic annotation 213548_s_at BG257762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG257762 /FEA=EST /DB_XREF=gi:12767578 /DB_XREF=est:602377462F1 /CLONE=IMAGE:4508319 /UG=Hs.283690 hypothetical protein BG257762 CDV3 homolog (mouse) CDV3 55573 NM_001134422 /// NM_001134423 /// NM_001282762 /// NM_001282763 /// NM_001282764 /// NM_001282765 /// NM_017548 /// XM_005247588 /// XM_005247589 /// XM_005247590 /// XM_005247591 /// XM_005247592 /// XM_005247594 0008283 // cell proliferation // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 213549_at AI890972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI890972 /FEA=EST /DB_XREF=gi:5596136 /DB_XREF=est:wm93f11.x1 /CLONE=IMAGE:2443533 /UG=Hs.194110 hypothetical protein PRO2730 AI890972 PDZ domain containing 8 PDZD8 118987 NM_173791 /// XM_005269518 /// XR_246069 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213550_s_at AA993683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA993683 /FEA=EST /DB_XREF=gi:3180228 /DB_XREF=est:ot97b04.s1 /CLONE=IMAGE:1624687 /UG=Hs.163867 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8) AA993683 IK cytokine, down-regulator of HLA II /// transmembrane and coiled-coil domains 6 IK /// TMCO6 3550 /// 55374 NM_006083 /// NM_018502 /// XM_005268476 /// XM_005268477 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 213551_x_at AI744229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744229 /FEA=EST /DB_XREF=gi:5112517 /DB_XREF=est:tr07g08.x1 /CLONE=IMAGE:2217662 /UG=Hs.184669 zinc finger protein 144 (Mel-18) AI744229 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213552_at W87398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87398 /FEA=EST /DB_XREF=gi:1401453 /DB_XREF=est:zh66h10.s1 /CLONE=IMAGE:417091 /UG=Hs.183006 KIAA0836 protein W87398 glucuronic acid epimerase GLCE 26035 NM_015554 /// XM_005254298 /// XM_005254299 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0030210 // heparin biosynthetic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from sequence or structural similarity /// 0047464 // heparosan-N-sulfate-glucuronate 5-epimerase activity // inferred from mutant phenotype /// 0050379 // UDP-glucuronate 5'-epimerase activity // inferred from direct assay 213553_x_at W79394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W79394 /FEA=EST /DB_XREF=gi:1390665 /DB_XREF=est:zd80c07.s1 /CLONE=IMAGE:346956 /UG=Hs.268571 apolipoprotein C-I W79394 apolipoprotein C-I APOC1 341 NM_001645 /// XM_005258855 0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010873 // positive regulation of cholesterol esterification // traceable author statement /// 0010900 // negative regulation of phosphatidylcholine catabolic process // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0032374 // regulation of cholesterol transport // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034369 // plasma lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // traceable author statement /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from genetic interaction /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // traceable author statement /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // traceable author statement 213554_s_at AI928407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI928407 /FEA=EST /DB_XREF=gi:5664371 /DB_XREF=est:wo96h09.x1 /CLONE=IMAGE:2463233 /UG=Hs.283690 hypothetical protein AI928407 CDV3 homolog (mouse) CDV3 55573 NM_001134422 /// NM_001134423 /// NM_001282762 /// NM_001282763 /// NM_001282764 /// NM_001282765 /// NM_017548 /// XM_005247588 /// XM_005247589 /// XM_005247590 /// XM_005247591 /// XM_005247592 /// XM_005247594 0008283 // cell proliferation // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 213555_at AL049699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049699 /DEF=Human DNA sequence from clone 747H23 on chromosome 6q13-15. Contains the 3 part of the ME1 gene for malic enzyme 1, soluble (NADP-dependent malic enzyme, malate oxidoreductase, EC 1.1.1.40), a novel gene and the 5 part of the gene for N-acetylgl... /FEA=mRNA_2 /DB_XREF=gi:5419832 /UG=Hs.26771 Human DNA sequence from clone 747H23 on chromosome 6q13-15. Contains the 3 part of the ME1 gene for malic enzyme 1, soluble (NADP-dependent malic enzyme, malate oxidoreductase, EC 1.1.1.40), a novel gene and the 5 part of the gene for N-acetylglucosamin AL049699 RWD domain containing 2A RWDD2A 112611 NM_033411 /// XM_005248648 /// XM_006715323 /// XM_006715324 0005515 // protein binding // inferred from electronic annotation 213556_at BE673445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE673445 /FEA=EST /DB_XREF=gi:10033986 /DB_XREF=est:7d35d10.x1 /CLONE=IMAGE:3249235 /UG=Hs.22049 Homo sapiens chromosome 19, cosmid R28379 BE673445 phospholipase A2 inhibitor and LY6/PLAUR domain containing PINLYP 390940 NM_001193621 /// NM_001193622 /// XM_005258931 /// XM_006723214 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // inferred from electronic annotation 213557_at AW305119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW305119 /FEA=EST /DB_XREF=gi:6717322 /DB_XREF=est:xv99g09.x1 /CLONE=IMAGE:2826688 /UG=Hs.278346 KIAA0904 protein AW305119 cyclin-dependent kinase 12 CDK12 51755 NM_015083 /// NM_016507 /// XM_005257456 /// XM_005257458 /// XR_429896 /// XR_429897 /// XR_429898 /// XR_429899 /// XR_429900 /// XR_429901 /// XR_429902 /// XR_429903 /// XR_429904 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043405 // regulation of MAP kinase activity // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from mutant phenotype 0002944 // cyclin K-CDK12 complex // inferred from physical interaction /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from mutant phenotype /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 213558_at AB011131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011131.1 /DEF=Homo sapiens mRNA for KIAA0559 protein, partial cds. /FEA=mRNA /GEN=KIAA0559 /PROD=KIAA0559 protein /DB_XREF=gi:3043641 /UG=Hs.12376 piccolo (presynaptic cytomatrix protein) AB011131 piccolo presynaptic cytomatrix protein PCLO 27445 NM_014510 /// NM_033026 /// XM_006715926 0006810 // transport // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // non-traceable author statement /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005856 // cytoskeleton // non-traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from sequence or structural similarity /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213559_s_at BF223401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223401 /FEA=EST /DB_XREF=gi:11130578 /DB_XREF=est:7q87h04.x1 /CLONE=IMAGE:3705462 /UG=Hs.112158 Homo sapiens PAC clone RP4-751H13 from 7q35-qter BF223401 zinc finger protein 467 ZNF467 168544 NM_207336 /// XM_005249959 /// XM_005249960 /// XM_005249961 /// XM_006715864 /// XM_006715865 /// XM_006715866 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213560_at AV658684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV658684 /FEA=EST /DB_XREF=gi:9879698 /DB_XREF=est:AV658684 /CLONE=GLCFPA11 /UG=Hs.110571 growth arrest and DNA-damage-inducible, beta AV658684 growth arrest and DNA-damage-inducible, beta GADD45B 4616 NM_015675 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213561_at BF062335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062335 /FEA=EST /DB_XREF=gi:10821245 /DB_XREF=est:7k76h10.x1 /CLONE=IMAGE:3481579 /UG=Hs.108110 DKFZP547E2110 protein BF062335 minichromosome maintenance complex component 9 MCM9 254394 NM_017696 /// NM_153255 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0007292 // female gamete generation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0097362 // MCM8-MCM9 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 213562_s_at BF979497 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF979497 /FEA=EST /DB_XREF=gi:12346816 /DB_XREF=est:602288121F1 /CLONE=IMAGE:4373861 /UG=Hs.71465 squalene epoxidase BF979497 squalene epoxidase SQLE 6713 NM_003129 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004506 // squalene monooxygenase activity // non-traceable author statement /// 0004506 // squalene monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 213563_s_at AA016035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA016035 /FEA=EST /DB_XREF=gi:1477064 /DB_XREF=est:ze31b08.s1 /CLONE=IMAGE:360567 /UG=Hs.13386 gamma-tubulin complex protein 2 AA016035 tubulin, gamma complex associated protein 2 TUBGCP2 10844 NM_001256617 /// NM_001256618 /// NM_006659 /// NR_046330 /// XM_006717596 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005881 // cytoplasmic microtubule // traceable author statement 0005515 // protein binding // inferred from physical interaction 213564_x_at BE042354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE042354 /FEA=EST /DB_XREF=gi:8359407 /DB_XREF=est:ho19b09.x1 /CLONE=IMAGE:3037817 /UG=Hs.234489 lactate dehydrogenase B BE042354 lactate dehydrogenase B LDHB 3945 NM_001174097 /// NM_002300 /// XM_006719074 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004457 // lactate dehydrogenase activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 213565_s_at AI193899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI193899 /FEA=EST /DB_XREF=gi:3745108 /DB_XREF=est:qe80f08.x1 /CLONE=IMAGE:1745319 /UG=Hs.153863 MAD (mothers against decapentaplegic, Drosophila) homolog 6 AI193899 SMAD family member 6 SMAD6 4091 NM_001142861 /// NM_005585 /// NR_027654 0001657 // ureteric bud development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from direct assay /// 0030617 // transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity // inferred from mutant phenotype /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070698 // type I activin receptor binding // inferred from direct assay 213566_at NM_005615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005615.1 /DEF=Homo sapiens ribonuclease, RNase A family, k6 (RNASE6), mRNA. /FEA=CDS /GEN=RNASE6 /PROD=ribonuclease, RNase A family, k6 /DB_XREF=gi:5032044 /UG=Hs.23262 ribonuclease, RNase A family, k6 /FL=gb:NM_005615.1 NM_005615 ribonuclease, RNase A family, k6 RNASE6 6039 NM_005615 0006401 // RNA catabolic process // traceable author statement /// 0006952 // defense response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation 213567_at BF431965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431965 /FEA=EST /DB_XREF=gi:11444079 /DB_XREF=est:nab83d09.x1 /CLONE=IMAGE:3274409 /UG=Hs.153106 Homo sapiens clone 23728 mRNA sequence BF431965 karyopherin alpha 4 (importin alpha 3) KPNA4 3840 NM_002268 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 213568_at AI811298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI811298 /FEA=EST /DB_XREF=gi:5397864 /DB_XREF=est:tw38a08.x1 /CLONE=IMAGE:2261942 /UG=Hs.143600 type II Golgi membrane protein AI811298 odd-skipped related transciption factor 2 OSR2 116039 NM_001142462 /// NM_001286841 /// NM_053001 /// XM_005250778 /// XM_005250779 /// XM_006716504 /// XM_006716505 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0033687 // osteoblast proliferation // inferred from sequence or structural similarity /// 0035115 // embryonic forelimb morphogenesis // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0036023 // embryonic skeletal limb joint morphogenesis // inferred from sequence or structural similarity /// 0042474 // middle ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048793 // pronephros development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060272 // embryonic skeletal joint morphogenesis // inferred from sequence or structural similarity /// 0060322 // head development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0072498 // embryonic skeletal joint development // inferred from sequence or structural similarity /// 2000543 // positive regulation of gastrulation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213569_at AV705485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705485 /FEA=EST /DB_XREF=gi:10722786 /DB_XREF=est:AV705485 /CLONE=ADBCNA10 /UG=Hs.155182 KIAA1036 protein AV705485 uncharacterized LOC100506603 LOC100506603 100506603 NR_104183 /// NR_104184 213570_at BF516289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF516289 /FEA=EST /DB_XREF=gi:11601468 /DB_XREF=est:UI-H-BW1-anz-d-07-0-UI.s1 /CLONE=IMAGE:3083964 /UG=Hs.19122 eukaryotic translation initiation factor 4E-like 3 BF516289 eukaryotic translation initiation factor 4E family member 2 EIF4E2 9470 NM_001276336 /// NM_001276337 /// NM_001282958 /// NM_004846 /// XM_005246975 /// XR_427124 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213571_s_at BF516289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF516289 /FEA=EST /DB_XREF=gi:11601468 /DB_XREF=est:UI-H-BW1-anz-d-07-0-UI.s1 /CLONE=IMAGE:3083964 /UG=Hs.19122 eukaryotic translation initiation factor 4E-like 3 BF516289 eukaryotic translation initiation factor 4E family member 2 EIF4E2 9470 NM_001276336 /// NM_001276337 /// NM_001282958 /// NM_004846 /// XM_005246975 /// XR_427124 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213572_s_at AI554300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI554300 /FEA=EST /DB_XREF=gi:4486663 /DB_XREF=est:tq05e07.x1 /CLONE=IMAGE:2207940 /UG=Hs.183583 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 AI554300 serpin peptidase inhibitor, clade B (ovalbumin), member 1 SERPINB1 1992 NM_030666 /// NR_073111 /// NR_073112 /// XM_006715008 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 213573_at AA861608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA861608 /FEA=EST /DB_XREF=gi:2953748 /DB_XREF=est:ak34e01.s1 /CLONE=IMAGE:1407864 /UG=Hs.180446 karyopherin (importin) beta 1 AA861608 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213574_s_at AA861608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA861608 /FEA=EST /DB_XREF=gi:2953748 /DB_XREF=est:ak34e01.s1 /CLONE=IMAGE:1407864 /UG=Hs.180446 karyopherin (importin) beta 1 AA861608 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213575_at AA831170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA831170 /FEA=EST /DB_XREF=gi:2904269 /DB_XREF=est:oc73b02.s1 /CLONE=IMAGE:1355307 /UG=Hs.24937 transformer-2 alpha (htra-2 alpha) AA831170 transformer 2 alpha homolog (Drosophila) TRA2A 29896 NM_001282757 /// NM_001282758 /// NM_001282759 /// NM_013293 /// XM_005249725 /// XM_006715713 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213577_at AA639705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA639705 /FEA=EST /DB_XREF=gi:2563484 /DB_XREF=est:np60h03.s1 /CLONE=IMAGE:1130741 /UG=Hs.71465 squalene epoxidase AA639705 squalene epoxidase SQLE 6713 NM_003129 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004506 // squalene monooxygenase activity // non-traceable author statement /// 0004506 // squalene monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 213578_at AI678679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI678679 /FEA=EST /DB_XREF=gi:4888861 /DB_XREF=est:tu58f02.x1 /CLONE=IMAGE:2255259 /UG=Hs.2534 bone morphogenetic protein receptor, type IA AI678679 bone morphogenetic protein receptor, type IA BMPR1A 657 NM_004329 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003272 // endocardial cushion formation // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021998 // neural plate mediolateral regionalization // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048352 // paraxial mesoderm structural organization // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048382 // mesendoderm development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060896 // neural plate pattern specification // inferred from electronic annotation /// 0060914 // heart formation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // traceable author statement /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213579_s_at AI459462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI459462 /FEA=EST /DB_XREF=gi:4312343 /DB_XREF=est:ar86e07.x1 /CLONE=IMAGE:2152164 /UG=Hs.25272 E1A binding protein p300 AI459462 E1A binding protein p300 EP300 2033 NM_001429 /// XM_006724165 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0043969 // histone H2B acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0090043 // regulation of tubulin deacetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 213580_at AA521272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521272 /FEA=EST /DB_XREF=gi:2261815 /DB_XREF=est:aa75f09.s1 /CLONE=IMAGE:826793 /UG=Hs.29417 HCF-binding transcription factor Zhangfei AA521272 213581_at BF446180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF446180 /FEA=EST /DB_XREF=gi:11511318 /DB_XREF=est:7p33e08.x1 /CLONE=IMAGE:3647703 /UG=Hs.41639 programmed cell death 2 BF446180 programmed cell death 2 PDCD2 5134 NM_001199461 /// NM_001199462 /// NM_001199463 /// NM_001199464 /// NM_002598 /// NM_144781 /// XM_006715498 /// XR_427972 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213582_at BF439472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF439472 /FEA=EST /DB_XREF=gi:11451989 /DB_XREF=est:nab65a05.x1 /CLONE=IMAGE:3272361 /UG=Hs.29189 ATPase, Class VI, type 11A BF439472 ATPase, class VI, type 11A ATP11A 23250 NM_015205 /// NM_032189 /// XM_005268299 /// XM_005268300 /// XM_005268301 /// XM_005268303 /// XM_005268305 /// XM_005268306 /// XM_006719965 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation 213583_x_at BE964125 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964125 /FEA=EST /DB_XREF=gi:11767593 /DB_XREF=est:601657809R1 /CLONE=IMAGE:3875978 /UG=Hs.288036 tRNA isopentenylpyrophosphate transferase BE964125 eukaryotic translation elongation factor 1 alpha 1 EEF1A1 1915 NM_001402 /// NM_001403 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213584_s_at AI432137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI432137 /FEA=EST /DB_XREF=gi:4308076 /DB_XREF=est:tg77b01.x1 /CLONE=IMAGE:2114761 /UG=Hs.29417 HCF-binding transcription factor Zhangfei AI432137 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213585_s_at AA764988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA764988 /FEA=EST /DB_XREF=gi:2816226 /DB_XREF=est:nz77e05.s1 /CLONE=IMAGE:1301504 /UG=Hs.41639 programmed cell death 2 AA764988 programmed cell death 2 PDCD2 5134 NM_001199461 /// NM_001199462 /// NM_001199463 /// NM_001199464 /// NM_002598 /// NM_144781 /// XM_006715498 /// XR_427972 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213586_at AI401296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI401296 /FEA=EST /DB_XREF=gi:4244383 /DB_XREF=est:tg92c03.x1 /CLONE=IMAGE:2116228 /UG=Hs.29656 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) AI401296 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) CDKN2D 1032 NM_001800 /// NM_079421 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0033280 // response to vitamin D // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 213587_s_at AI884867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI884867 /FEA=EST /DB_XREF=gi:5590031 /DB_XREF=est:wl85g03.x1 /CLONE=IMAGE:2431732 /UG=Hs.91379 ribosomal protein L26 AI884867 ATPase, H+ transporting V0 subunit e2 ATP6V0E2 155066 NM_001100592 /// NM_001289990 /// NM_145230 /// NR_110612 /// XM_005249958 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 213588_x_at AA838274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA838274 /FEA=EST /DB_XREF=gi:2913073 /DB_XREF=est:oe90c01.s1 /CLONE=IMAGE:1418880 /UG=Hs.738 ribosomal protein L14 AA838274 ribosomal protein L14 RPL14 9045 NM_001034996 /// NM_003973 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213589_s_at AW468201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW468201 /FEA=EST /DB_XREF=gi:7038307 /DB_XREF=est:he34a04.x1 /CLONE=IMAGE:2920878 /UG=Hs.91375 Human clone 23614 mRNA sequence AW468201 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 B3GNTL1 146712 NM_001009905 /// XM_006722272 /// XM_006722273 /// XM_006722274 /// XM_006725289 /// XM_006725290 /// XR_243519 /// XR_430780 0008152 // metabolic process // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 213590_at AA705628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA705628 /FEA=EST /DB_XREF=gi:2715546 /DB_XREF=est:zf40a01.s1 /CLONE=IMAGE:379368 /UG=Hs.90911 solute carrier family 16 (monocarboxylic acid transporters), member 5 AA705628 solute carrier family 16 (monocarboxylate transporter), member 5 SLC16A5 9121 NM_001271765 /// NM_004695 /// XM_005257790 /// XM_005257791 /// XM_006722170 0006810 // transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation 213591_at AU149534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149534 /FEA=EST /DB_XREF=gi:11011055 /DB_XREF=est:AU149534 /CLONE=NT2RM4002512 /UG=Hs.74294 aldehyde dehydrogenase 7 family, member A1 AU149534 aldehyde dehydrogenase 7 family, member A1 ALDH7A1 501 NM_001182 /// NM_001201377 /// NM_001202404 0006081 // cellular aldehyde metabolic process // inferred from sequence or structural similarity /// 0006554 // lysine catabolic process // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019285 // glycine betaine biosynthetic process from choline // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from sequence or structural similarity /// 0004043 // L-aminoadipate-semialdehyde dehydrogenase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008802 // betaine-aldehyde dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 213592_at X89271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89271.1 /DEF=H.sapiens mRNA for HG11 orphan receptor. /FEA=mRNA /GEN=HG11 /PROD=HG11 orphan receptor /DB_XREF=gi:6911643 /UG=Hs.9305 angiotensin receptor-like 1 /FL=gb:NM_005161.1 X89271 apelin receptor APLNR 187 NM_005161 /// NR_027991 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 213593_s_at AW978896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW978896 /FEA=EST /DB_XREF=gi:8170173 /DB_XREF=est:EST391005 /UG=Hs.24937 transformer-2 alpha (htra-2 alpha) AW978896 transformer 2 alpha homolog (Drosophila) TRA2A 29896 NM_001282757 /// NM_001282758 /// NM_001282759 /// NM_013293 /// XM_005249725 /// XM_006715713 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213594_x_at AU130523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU130523 /FEA=EST /DB_XREF=gi:10990877 /DB_XREF=est:AU130523 /CLONE=NT2RP3000977 /UG=Hs.3530 TLS-associated serine-arginine protein 2 AU130523 serine/arginine-rich splicing factor 10 SRSF10 10772 NM_001191005 /// NM_001191006 /// NM_001191007 /// NM_001191009 /// NM_006625 /// NM_054016 /// NR_034035 /// XM_006710298 /// XM_006710299 /// XM_006710300 /// XM_006710301 0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 213595_s_at AA127643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA127643 /FEA=EST /DB_XREF=gi:1686967 /DB_XREF=est:zk92f02.s1 /CLONE=IMAGE:490299 /UG=Hs.326691 Homo sapiens KIAA0451 gene product (KIAA0451), mRNA AA127643 CDC42 binding protein kinase alpha (DMPK-like) CDC42BPA 8476 NM_003607 /// NM_014826 /// XM_005273317 /// XM_005273318 /// XM_005273320 /// XM_005273321 /// XM_005273322 /// XM_005273323 /// XM_005273324 /// XM_006711834 /// XM_006711835 /// XM_006711836 /// XM_006711837 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007097 // nuclear migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213596_at AL050391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050391.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586A181 (from clone DKFZp586A181); partial cds. /FEA=mRNA /GEN=DKFZp586A181 /PROD=hypothetical protein /DB_XREF=gi:4914591 /UG=Hs.321247 Homo sapiens mRNA; cDNA DKFZp586A181 (from clone DKFZp586A181); partial cds AL050391 caspase 4, apoptosis-related cysteine peptidase CASP4 837 NM_001225 /// NM_033306 /// NM_033307 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // not recorded /// 0097194 // execution phase of apoptosis // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0072557 // IPAF inflammasome complex // not recorded /// 0072559 // NLRP3 inflammasome complex // not recorded /// 0097169 // AIM2 inflammasome complex // not recorded 0004197 // cysteine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213597_s_at BF002474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002474 /FEA=EST /DB_XREF=gi:10702749 /DB_XREF=est:7h07c07.x1 /CLONE=IMAGE:3315276 /UG=Hs.147189 HYA22 protein BF002474 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213598_at W87688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87688 /FEA=EST /DB_XREF=gi:1401813 /DB_XREF=est:zh68c03.s1 /CLONE=IMAGE:417220 /UG=Hs.125819 putative dimethyladenosine transferase W87688 213599_at BE045993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE045993 /FEA=EST /DB_XREF=gi:8363046 /DB_XREF=est:hd91c08.x4 /CLONE=IMAGE:2916878 /UG=Hs.116206 Opa-interacting protein 5 BE045993 Opa interacting protein 5 OIP5 11339 NM_007280 0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213600_at AA425633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA425633 /FEA=EST /DB_XREF=gi:2107236 /DB_XREF=est:zv47a01.s1 /CLONE=IMAGE:756744 /UG=Hs.129943 KIAA0545 protein AA425633 signal-induced proliferation-associated 1 like 3 SIPA1L3 23094 NM_015073 /// XM_005258671 /// XM_005258672 /// XM_006723112 /// XR_430194 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213601_at AB011537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011537.2 /DEF=Homo sapiens mRNA for MEGF4, partial cds. /FEA=mRNA /GEN=MEGF4 /PROD=MEGF4 /DB_XREF=gi:6683648 /UG=Hs.133466 slit (Drosophila) homolog 1 AB011537 slit homolog 1 (Drosophila) SLIT1 6585 NM_003061 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0048853 // forebrain morphogenesis // non-traceable author statement /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051964 // negative regulation of synapse assembly // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 213602_s_at AA401885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA401885 /FEA=EST /DB_XREF=gi:2055904 /DB_XREF=est:zt44a11.s1 /CLONE=IMAGE:725180 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) AA401885 213603_s_at BE138888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE138888 /FEA=EST /DB_XREF=gi:8601388 /DB_XREF=est:xw97c06.x1 /CLONE=IMAGE:2835946 /UG=Hs.301175 HSPC022 protein BE138888 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) RAC2 5880 NM_002872 /// XM_006724286 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010310 // regulation of hydrogen peroxide metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0045453 // bone resorption // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0060263 // regulation of respiratory burst // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 213604_at AW451236 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451236 /FEA=EST /DB_XREF=gi:6992012 /DB_XREF=est:UI-H-BI3-alh-a-07-0-UI.s1 /CLONE=IMAGE:2736661 /UG=Hs.15535 Homo sapiens clone 24582 mRNA sequence AW451236 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) TCEB3 6924 NM_003198 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213605_s_at AL049987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049987.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F112 (from clone DKFZp564F112). /FEA=mRNA /DB_XREF=gi:4884238 /UG=Hs.166361 Homo sapiens mRNA; cDNA DKFZp564F112 (from clone DKFZp564F112) AL049987 213606_s_at AI571798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI571798 /FEA=EST /DB_XREF=gi:4535172 /DB_XREF=est:tn19h05.x1 /CLONE=IMAGE:2168121 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha AI571798 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213607_x_at BE551347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551347 /FEA=EST /DB_XREF=gi:9793039 /DB_XREF=est:7b63d11.x1 /CLONE=IMAGE:3232917 /UG=Hs.220324 hypothetical protein FLJ13052 BE551347 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213608_s_at AI220627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI220627 /FEA=EST /DB_XREF=gi:3802830 /DB_XREF=est:qg01a03.x1 /CLONE=IMAGE:1758220 /UG=Hs.20225 tuftelin-interacting protein AI220627 SRR1 domain containing SRRD 402055 NM_001013694 0048511 // rhythmic process // inferred from electronic annotation 213609_s_at AB023144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023144.1 /DEF=Homo sapiens mRNA for KIAA0927 protein, partial cds. /FEA=mRNA /GEN=KIAA0927 /PROD=KIAA0927 protein /DB_XREF=gi:4589485 /UG=Hs.194766 seizure related gene 6 (mouse)-like AB023144 seizure related 6 homolog (mouse)-like SEZ6L 23544 NM_001184773 /// NM_001184774 /// NM_001184775 /// NM_001184776 /// NM_001184777 /// NM_021115 /// XM_005261439 /// XM_005261440 /// XM_006724195 /// XM_006724196 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 213610_s_at BE326381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE326381 /FEA=EST /DB_XREF=gi:9200157 /DB_XREF=est:hw02e08.x1 /CLONE=IMAGE:3181766 /UG=Hs.18724 Homo sapiens mRNA; cDNA DKFZp564F093 (from clone DKFZp564F093) BE326381 kelch-like family member 23 /// PHOSPHO2-KLHL23 readthrough KLHL23 /// PHOSPHO2-KLHL23 151230 /// 100526832 NM_001199290 /// NM_144711 0005515 // protein binding // inferred from electronic annotation 213611_at BF726531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF726531 /FEA=EST /DB_XREF=gi:12042442 /DB_XREF=est:by08a01.y1 /CLONE=by08a01 /UG=Hs.298023 aquaporin 5 /FL=gb:NM_001651.1 BF726531 aquaporin 5 AQP5 362 NM_001651 /// XM_005268838 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015670 // carbon dioxide transport // inferred from direct assay /// 0030157 // pancreatic juice secretion // inferred from expression pattern /// 0042476 // odontogenesis // inferred from expression pattern /// 0046541 // saliva secretion // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015250 // water channel activity // inferred from direct assay 213612_x_at AI800419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI800419 /FEA=EST /DB_XREF=gi:5365891 /DB_XREF=est:tj14b09.x1 /CLONE=IMAGE:2141465 /UG=Hs.218329 hypothetical protein AI800419 neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 12 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9 NBPF10 /// NBPF12 /// NBPF14 /// NBPF15 /// NBPF20 /// NBPF8 /// NBPF9 25832 /// 149013 /// 284565 /// 400818 /// 728841 /// 100132406 /// 100288142 NM_001037501 /// NM_001037675 /// NM_001039703 /// NM_001102663 /// NM_001170755 /// NM_001277444 /// NM_001278141 /// NM_001278267 /// NM_015383 /// NM_173638 /// NR_102404 /// NR_102405 /// XM_005245096 /// XM_005245097 /// XM_005277342 /// XM_005277343 /// XM_005277344 /// XM_005277345 /// XM_005277346 /// XM_005277347 /// XM_006710872 /// XM_006711103 /// XM_006711104 /// XM_006711179 /// XM_006711180 /// XM_006711181 /// XM_006711182 /// XM_006711265 /// XM_006711317 /// XR_254328 /// XR_426769 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 213613_s_at BE551347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551347 /FEA=EST /DB_XREF=gi:9793039 /DB_XREF=est:7b63d11.x1 /CLONE=IMAGE:3232917 /UG=Hs.220324 hypothetical protein FLJ13052 BE551347 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213614_x_at BE786672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE786672 /FEA=EST /DB_XREF=gi:10207870 /DB_XREF=est:601475022F1 /CLONE=IMAGE:3878140 /UG=Hs.284136 PRO2047 protein BE786672 eukaryotic translation elongation factor 1 alpha 1 EEF1A1 1915 NM_001402 /// NM_001403 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213615_at AA773554 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA773554 /FEA=EST /DB_XREF=gi:2825125 /DB_XREF=est:ab61a05.s1 /CLONE=IMAGE:845264 /UG=Hs.234216 Human 40871 mRNA partial sequence AA773554 lysophosphatidylcholine acyltransferase 3 /// LPCAT3 /// U47924.30 10162 NM_005768 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0097006 // regulation of plasma lipoprotein particle levels // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from mutant phenotype 213616_at BF063896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF063896 /FEA=EST /DB_XREF=gi:10822806 /DB_XREF=est:7h90a05.x1 /CLONE=IMAGE:3323216 /UG=Hs.22981 DKFZP586M1523 protein BF063896 tubulin polyglutamylase complex subunit 2 TPGS2 25941 NM_001271949 /// NM_001271950 /// NM_001271951 /// NM_001271952 /// NM_001271953 /// NM_001271954 /// NM_001271955 /// NM_001271956 /// NM_015476 /// XM_005258242 /// XR_243849 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 213617_s_at BF063896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF063896 /FEA=EST /DB_XREF=gi:10822806 /DB_XREF=est:7h90a05.x1 /CLONE=IMAGE:3323216 /UG=Hs.22981 DKFZP586M1523 protein BF063896 tubulin polyglutamylase complex subunit 2 TPGS2 25941 NM_001271949 /// NM_001271950 /// NM_001271951 /// NM_001271952 /// NM_001271953 /// NM_001271954 /// NM_001271955 /// NM_001271956 /// NM_015476 /// XM_005258242 /// XR_243849 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 213618_at AB011152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011152.1 /DEF=Homo sapiens mRNA for KIAA0580 protein, partial cds. /FEA=mRNA /GEN=KIAA0580 /PROD=KIAA0580 protein /DB_XREF=gi:3043683 /UG=Hs.22572 KIAA0580 protein AB011152 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 /// uncharacterized LOC101928667 ARAP2 /// LOC101928667 116984 /// 101928667 NM_015230 /// NM_139182 /// XM_005262638 /// XM_005262640 /// XM_005262642 /// XM_005262643 /// XM_006713991 /// XR_244603 /// XR_249580 /// XR_251565 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213619_at AV753392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV753392 /FEA=EST /DB_XREF=gi:10911240 /DB_XREF=est:AV753392 /CLONE=NPDAUG03 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) AV753392 213620_s_at AA126728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA126728 /FEA=EST /DB_XREF=gi:1686292 /DB_XREF=est:zk95d07.s1 /CLONE=IMAGE:490573 /UG=Hs.83733 intercellular adhesion molecule 2 AA126728 intercellular adhesion molecule 2 ICAM2 3384 NM_000873 /// NM_001099786 /// NM_001099787 /// NM_001099788 /// NM_001099789 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0001931 // uropod // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005178 // integrin binding // inferred from physical interaction 213621_s_at AW182892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW182892 /FEA=EST /DB_XREF=gi:6451352 /DB_XREF=est:xp99c02.x1 /CLONE=IMAGE:2748482 /UG=Hs.3764 guanylate kinase 1 AW182892 guanylate kinase 1 GUK1 2987 NM_000858 /// NM_001159390 /// NM_001159391 /// NM_001242839 /// NM_001242840 /// XM_005273103 /// XM_005273104 /// XM_005273105 /// XM_005273106 0006163 // purine nucleotide metabolic process // inferred from direct assay /// 0006185 // dGDP biosynthetic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0017144 // drug metabolic process // traceable author statement /// 0019673 // GDP-mannose metabolic process // inferred from electronic annotation /// 0034436 // glycoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046037 // GMP metabolic process // inferred from electronic annotation /// 0046054 // dGMP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046711 // GDP biosynthetic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004385 // guanylate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation 213622_at AI733465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI733465 /FEA=EST /DB_XREF=gi:5054578 /DB_XREF=est:oq93g07.x5 /CLONE=IMAGE:1593948 /UG=Hs.37165 collagen, type IX, alpha 2 /FL=gb:NM_001852.1 AI733465 collagen, type IX, alpha 2 COL9A2 1298 NM_001852 /// XM_005270480 /// XM_006710365 0001501 // skeletal system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005594 // collagen type IX trimer // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0030020 // extracellular matrix structural constituent conferring tensile strength // inferred by curator 213623_at NM_007054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007054.1 /DEF=Homo sapiens kinesin family member 3A (KIF3A), mRNA. /FEA=CDS /GEN=KIF3A /PROD=kinesin family member 3A /DB_XREF=gi:6857803 /UG=Hs.43670 kinesin family member 3A /FL=gb:AF041853.1 gb:NM_007054.1 NM_007054 kinesin family member 3A KIF3A 11127 NM_007054 /// XM_005271868 /// XM_005271869 /// XM_006714526 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072383 // plus-end-directed vesicle transport along microtubule // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016939 // kinesin II complex // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008574 // plus-end-directed microtubule motor activity // traceable author statement /// 0030507 // spectrin binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 213624_at AA873600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA873600 /FEA=EST /DB_XREF=gi:2969722 /DB_XREF=est:ob12a02.s1 /CLONE=IMAGE:1323434 /UG=Hs.42945 acid sphingomyelinase-like phosphodiesterase AA873600 sphingomyelin phosphodiesterase, acid-like 3A SMPDL3A 10924 NM_001286138 /// NM_006714 /// XM_005266797 /// XM_005266798 /// XM_005266799 /// XM_005266801 /// XM_005266802 0006685 // sphingomyelin catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 213625_at AW190088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190088 /FEA=EST /DB_XREF=gi:6464568 /DB_XREF=est:xl11h09.x1 /CLONE=IMAGE:2675969 /UG=Hs.44720 hypothetical protein P1 p373c6 /FL=gb:NM_019110.1 AW190088 zinc finger with KRAB and SCAN domains 4 ZKSCAN4 387032 NM_019110 /// XM_005249095 /// XM_005249097 /// XM_005249098 /// XM_005249099 /// XM_005249100 /// XM_005249101 /// XM_006715095 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213626_at AL049442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049442.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N1720 (from clone DKFZp586N1720). /FEA=mRNA /DB_XREF=gi:4500222 /UG=Hs.71616 Homo sapiens mRNA; cDNA DKFZp586N1720 (from clone DKFZp586N1720) AL049442 carbonyl reductase 4 CBR4 84869 NM_032783 /// XM_005263315 /// XM_005263316 /// XM_006714391 /// XM_006714392 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008753 // NADPH dehydrogenase (quinone) activity // inferred from direct assay /// 0008753 // NADPH dehydrogenase (quinone) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0048038 // quinone binding // inferred from direct assay /// 0048038 // quinone binding // inferred from sequence or structural similarity /// 0070402 // NADPH binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from sequence or structural similarity 213627_at AI924630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924630 /FEA=EST /DB_XREF=gi:5660594 /DB_XREF=est:wn57e10.x1 /CLONE=IMAGE:2449578 /UG=Hs.4943 hepatocellular carcinoma associated protein; breast cancer associated gene 1 AI924630 melanoma antigen family D, 2 MAGED2 10916 NM_014599 /// NM_177433 /// NM_201222 0016020 // membrane // inferred from direct assay 213628_at AA883493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA883493 /FEA=EST /DB_XREF=gi:2993023 /DB_XREF=est:am25g04.s1 /CLONE=IMAGE:1467894 /UG=Hs.93121 KIAA0761 protein AA883493 chloride channel CLIC-like 1 CLCC1 23155 NM_001048210 /// NM_001278202 /// NM_001278203 /// NM_015127 0006821 // chloride transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005254 // chloride channel activity // inferred from electronic annotation 213629_x_at BF246115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF246115 /FEA=EST /DB_XREF=gi:11160133 /DB_XREF=est:601854068F1 /CLONE=IMAGE:4073921 /UG=Hs.8765 RNA helicase-related protein BF246115 metallothionein 1F MT1F 4494 NM_005949 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213630_at AB002361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002361.1 /DEF=Human mRNA for KIAA0363 gene, partial cds. /FEA=mRNA /GEN=KIAA0363 /DB_XREF=gi:2224666 /UG=Hs.96633 KIAA0363 protein AB002361 NAC alpha domain containing NACAD 23148 NM_001146334 /// XM_006715674 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 213631_x_at BE789211 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE789211 /FEA=EST /DB_XREF=gi:10210409 /DB_XREF=est:601479952F1 /CLONE=IMAGE:3882661 /UG=Hs.94925 dihydroorotate dehydrogenase BE789211 dihydroorotate dehydrogenase (quinone) DHODH 1723 NM_001025193 /// NM_001361 /// XM_005255827 /// XM_005255828 /// XM_005255829 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090140 // regulation of mitochondrial fission // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004152 // dihydroorotate dehydrogenase activity // traceable author statement /// 0004158 // dihydroorotate oxidase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from electronic annotation 213632_at M94065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M94065.1 /DEF=Human dihydroorotate dehydrogenase mRNA, 3 end. /FEA=mRNA /PROD=dihydroorotate dehydrogenase /DB_XREF=gi:555593 /UG=Hs.94925 dihydroorotate dehydrogenase M94065 dihydroorotate dehydrogenase (quinone) DHODH 1723 NM_001025193 /// NM_001361 /// XM_005255827 /// XM_005255828 /// XM_005255829 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090140 // regulation of mitochondrial fission // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004152 // dihydroorotate dehydrogenase activity // traceable author statement /// 0004158 // dihydroorotate oxidase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from electronic annotation 213633_at NM_018957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_018957.1 /DEF=Homo sapiens SH3-domain binding protein 1 (SH3BP1), mRNA. /FEA=CDS /GEN=SH3BP1 /PROD=SH3-domain binding protein 1 /DB_XREF=gi:11545732 /UG=Hs.97858 SH3-domain binding protein 1 /FL=gb:NM_018957.1 NM_018957 SH3-domain binding protein 1 SH3BP1 23616 NM_018957 0007165 // signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 213634_s_at AL031588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031588 /DEF=Human DNA sequence from clone 1163J1 on chromosome 22q13.2-13.33. Contains the 3 part of a gene for a novel KIAA0279 LIKE EGF-like domain containing protein (similar to mouse Celsr1, rat MEGF2), a novel gene for a protein similar to C. elegans B0... /FEA=mRNA_1 /DB_XREF=gi:4007108 /UG=Hs.250671 hypothetical protein FLJ10140 AL031588 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase TRMU 55687 NM_001008569 /// NM_001008571 /// NM_001282782 /// NM_001282783 /// NM_001282784 /// NM_001282785 /// NM_018006 /// NR_104240 /// NR_104241 /// XM_005261678 /// XM_005261681 0006399 // tRNA metabolic process // non-traceable author statement /// 0006529 // asparagine biosynthetic process // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004066 // asparagine synthase (glutamine-hydrolyzing) activity // inferred from electronic annotation /// 0004808 // tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 213635_s_at AI761858 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI761858 /FEA=EST /DB_XREF=gi:5177525 /DB_XREF=est:wg68a12.x1 /CLONE=IMAGE:2370238 /UG=Hs.23978 scaffold attachment factor B AI761858 scaffold attachment factor B SAFB 6294 NM_001201338 /// NM_001201339 /// NM_001201340 /// NM_002967 /// NR_037699 /// XM_006722839 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213636_at AB028968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028968.1 /DEF=Homo sapiens mRNA for KIAA1045 protein, partial cds. /FEA=mRNA /GEN=KIAA1045 /PROD=KIAA1045 protein /DB_XREF=gi:5689426 /UG=Hs.7989 KIAA1045 protein AB028968 KIAA1045 KIAA1045 23349 NM_015297 /// XM_005251420 /// XR_242502 0046872 // metal ion binding // inferred from electronic annotation 213637_at BE503392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE503392 /FEA=EST /DB_XREF=gi:9705800 /DB_XREF=est:7a17e04.x1 /CLONE=IMAGE:3219006 /UG=Hs.145020 ESTs, Weakly similar to KIAA1205 protein H.sapiens BE503392 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 DDX52 11056 NM_001291476 /// NM_007010 /// NM_152300 /// XM_006721650 /// XM_006725299 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213638_at AW054711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW054711 /FEA=EST /DB_XREF=gi:5920414 /DB_XREF=est:wz96g08.x1 /CLONE=IMAGE:2566718 /UG=Hs.121591 Human DNA sequence from PAC 257A7 on chromosome 6p24. Contains two unknown genes and ESTs, STSs and a GSS AW054711 phosphatase and actin regulator 1 PHACTR1 221692 NM_001242648 /// NM_030948 /// XM_005248933 /// XM_005248934 /// XM_005248935 /// XM_005248936 /// XM_005248937 /// XM_006715021 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0048870 // cell motility // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation 213639_s_at AI871396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871396 /FEA=EST /DB_XREF=gi:5545445 /DB_XREF=est:wl81f07.x1 /CLONE=IMAGE:2431333 /UG=Hs.101414 KIAA0557 protein AI871396 zinc finger protein 500 ZNF500 26048 NM_021646 /// XM_005255243 /// XM_005255244 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213640_s_at BE503425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE503425 /FEA=EST /DB_XREF=gi:9705833 /DB_XREF=est:7a18b11.x1 /CLONE=IMAGE:3219069 /UG=Hs.102267 lysyl oxidase BE503425 lysyl oxidase LOX 4015 NM_001178102 /// NM_002317 0001568 // blood vessel development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0004720 // protein-lysine 6-oxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213641_at AB011129 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011129.1 /DEF=Homo sapiens mRNA for KIAA0557 protein, partial cds. /FEA=mRNA /GEN=KIAA0557 /PROD=KIAA0557 protein /DB_XREF=gi:3043637 /UG=Hs.101414 KIAA0557 protein AB011129 zinc finger protein 500 ZNF500 26048 NM_021646 /// XM_005255243 /// XM_005255244 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213642_at BE312027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE312027 /FEA=EST /DB_XREF=gi:9130191 /DB_XREF=est:601145652F1 /CLONE=IMAGE:3161124 /UG=Hs.111611 ribosomal protein L27 BE312027 213643_s_at AK022846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022846.1 /DEF=Homo sapiens cDNA FLJ12784 fis, clone NT2RP2001898, highly similar to Human inositol polyphosphate 5-phosphatase (5ptase) mRNA. /FEA=mRNA /DB_XREF=gi:10434476 /UG=Hs.182577 inositol polyphosphate-5-phosphatase, 75kD AK022846 inositol polyphosphate-5-phosphatase, 75kDa INPP5B 3633 NM_001297434 /// NM_005540 /// XM_005270833 /// XM_005270835 /// XM_005270836 /// XM_005270837 /// XM_006710619 /// XM_006710620 /// XM_006710621 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070613 // regulation of protein processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay 213644_at AI979276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI979276 /FEA=EST /DB_XREF=gi:5804295 /DB_XREF=est:wu03a04.x1 /CLONE=IMAGE:2515854 /UG=Hs.177482 ESTs, Weakly similar to KIAA1276 protein H.sapiens AI979276 centrosomal protein 112kDa CEP112 201134 NM_001037325 /// NM_001199165 /// NM_145036 /// XM_005257119 /// XM_005257122 /// XM_005257125 /// XM_005257126 /// XM_006721740 /// XM_006721741 /// XM_006721742 /// XM_006721743 /// XM_006721744 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0097120 // receptor localization to synapse // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0060077 // inhibitory synapse // inferred from electronic annotation 213645_at AF305057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF305057 /DEF=Homo sapiens RTS (RTS) gene, complete cds, alternatively spliced /FEA=mRNA_1 /DB_XREF=gi:11094017 /UG=Hs.180433 rTS beta protein AF305057 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 213646_x_at BE300252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE300252 /FEA=EST /DB_XREF=gi:9184000 /DB_XREF=est:600944004T1 /CLONE=IMAGE:2960280 /UG=Hs.240615 hypothetical protein FLJ13556 similar to N-myc downstream regulated 3 BE300252 tubulin, alpha 1b TUBA1B 10376 NM_006082 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 213647_at D42046 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D42046.1 /DEF=Human mRNA for KIAA0083 gene, partial cds. /FEA=mRNA /GEN=KIAA0083 /DB_XREF=gi:1531547 /UG=Hs.194665 DNA2 (DNA replication helicase, yeast, homolog)-like D42046 DNA replication helicase/nuclease 2 DNA2 1763 NM_001080449 /// NR_102264 /// XM_006717680 0000076 // DNA replication checkpoint // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006264 // mitochondrial DNA replication // inferred from direct assay /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0033567 // DNA replication, Okazaki fragment processing // inferred from direct assay /// 0043137 // DNA replication, removal of RNA primer // inferred from direct assay /// 0043504 // mitochondrial DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0004518 // nuclease activity // inferred from direct assay /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0016890 // site-specific endodeoxyribonuclease activity, specific for altered base // inferred from direct assay /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0043139 // 5'-3' DNA helicase activity // inferred from direct assay /// 0043142 // single-stranded DNA-dependent ATPase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 213648_at AW614427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW614427 /FEA=EST /DB_XREF=gi:7319613 /DB_XREF=est:hg82h04.x1 /CLONE=IMAGE:2952151 /UG=Hs.182877 KIAA0116 protein AW614427 exosome component 7 EXOSC7 23016 NM_015004 /// NR_023353 /// XM_006713035 /// XR_245104 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0006401 // RNA catabolic process // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213649_at AA524053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524053 /FEA=EST /DB_XREF=gi:2264981 /DB_XREF=est:ng33b07.s1 /CLONE=IMAGE:936565 /UG=Hs.184167 splicing factor, arginineserine-rich 7 (35kD) AA524053 serine/arginine-rich splicing factor 7 SRSF7 6432 NM_001031684 /// NM_001195446 /// NM_006276 /// XM_005264484 /// XM_005264485 /// XM_005264486 /// XR_426994 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213650_at AW006438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006438 /FEA=EST /DB_XREF=gi:5855216 /DB_XREF=est:wr16f06.x1 /CLONE=IMAGE:2481731 /UG=Hs.182982 golgin-67 AW006438 golgin A8 family, member A /// golgin A8 family, member B /// uncharacterized LOC101930583 GOLGA8A /// GOLGA8B /// LOC101930583 23015 /// 440270 /// 101930583 NM_001023567 /// NM_181077 /// NR_027409 /// NR_027410 /// XM_005254389 /// XM_005254391 /// XM_006720440 /// XM_006720530 /// XR_248092 /// XR_248093 /// XR_248094 /// XR_248096 /// XR_424599 /// XR_424600 /// XR_424601 /// XR_424602 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 213651_at AI935720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935720 /FEA=EST /DB_XREF=gi:5674590 /DB_XREF=est:wp01a05.x1 /CLONE=IMAGE:2463536 /UG=Hs.21492 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A AI935720 inositol polyphosphate-5-phosphatase J INPP5J 27124 NM_001002837 /// NM_001284285 /// NM_001284286 /// NM_001284287 /// NM_001284288 /// NM_001284289 /// NM_014422 /// XM_006724230 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0034485 // phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation 213652_at AU152579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU152579 /FEA=EST /DB_XREF=gi:11014100 /DB_XREF=est:AU152579 /CLONE=NT2RP3001232 /UG=Hs.288931 Homo sapiens cDNA FLJ13034 fis, clone NT2RP3001232 AU152579 proprotein convertase subtilisin/kexin type 5 PCSK5 5125 NM_001190482 /// NM_006200 /// NR_120409 /// XM_005252039 0001822 // kidney development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0002001 // renin secretion into blood stream // inferred from expression pattern /// 0006465 // signal peptide processing // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019058 // viral life cycle // inferred from expression pattern /// 0019058 // viral life cycle // inferred from sequence or structural similarity /// 0030323 // respiratory tube development // inferred from sequence or structural similarity /// 0032455 // nerve growth factor processing // traceable author statement /// 0035108 // limb morphogenesis // inferred from sequence or structural similarity /// 0042089 // cytokine biosynthetic process // inferred from sequence or structural similarity /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005796 // Golgi lumen // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity 213653_at AW069290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW069290 /FEA=EST /DB_XREF=gi:6024288 /DB_XREF=est:cr43g01.x1 /CLONE=HBMSC_cr43g01 /UG=Hs.268149 putative methyltransferase AW069290 methyltransferase like 3 METTL3 56339 NM_019852 /// XM_006720206 0001510 // RNA methylation // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0061157 // mRNA destabilization // inferred from sequence or structural similarity /// 0080009 // mRNA methylation // inferred from direct assay /// 0080009 // mRNA methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016422 // mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity // inferred from direct assay /// 0016422 // mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation 213654_at R60550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R60550 /FEA=EST /DB_XREF=gi:831245 /DB_XREF=est:yh14b04.s1 /CLONE=IMAGE:37736 /UG=Hs.26782 PCAF associated factor 65 beta /FL=gb:AF069736.1 gb:NM_014409.1 R60550 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa TAF5L 27097 NM_001025247 /// NM_014409 /// XM_005273099 /// XM_005273100 /// XM_005273101 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 213655_at AA502643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA502643 /FEA=EST /DB_XREF=gi:2237610 /DB_XREF=est:ne42g05.s1 /CLONE=IMAGE:900056 /UG=Hs.79474 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, epsilon polypeptide AA502643 213656_s_at BF593594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593594 /FEA=EST /DB_XREF=gi:11685918 /DB_XREF=est:7q12a08.x1 /CLONE=IMAGE:3697839 /UG=Hs.274440 Homo sapiens mRNA; cDNA DKFZp434I139 (from clone DKFZp434I139) BF593594 kinesin light chain 1 KLC1 3831 NM_001130107 /// NM_005552 /// NM_182923 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from electronic annotation 213657_s_at BE858194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE858194 /FEA=EST /DB_XREF=gi:10372818 /DB_XREF=est:7g19c05.x1 /CLONE=IMAGE:3306920 /UG=Hs.323053 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 26539 BE858194 Homo sapiens cDNA FLJ31419 fis, clone NT2NE2000356. /// AK055981 /// RP11-617F23.1 213658_at BE858194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE858194 /FEA=EST /DB_XREF=gi:10372818 /DB_XREF=est:7g19c05.x1 /CLONE=IMAGE:3306920 /UG=Hs.323053 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 26539 BE858194 Homo sapiens cDNA FLJ31419 fis, clone NT2NE2000356. AK055981 213659_at AA209420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA209420 /FEA=EST /DB_XREF=gi:1807363 /DB_XREF=est:zq84a08.s1 /CLONE=IMAGE:648278 /UG=Hs.29159 zinc finger protein 75 (D8C6) AA209420 zinc finger protein 75D ZNF75D 7626 NM_001185063 /// NM_007131 /// NR_110381 /// XM_005262469 /// XM_005262470 /// XM_005262471 /// XR_426550 /// XR_433782 /// XR_433783 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213660_s_at AA581879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA581879 /FEA=EST /DB_XREF=gi:2360557 /DB_XREF=est:nn43g06.s1 /CLONE=IMAGE:1086682 /UG=Hs.66191 Homo sapiens clone 24675 mRNA sequence AA581879 topoisomerase (DNA) III beta TOP3B 8940 NM_001282112 /// NM_001282113 /// NM_003935 /// XM_005261811 /// XM_005261813 /// XM_005261814 /// XM_006724349 /// XM_006724350 /// XM_006724351 /// XM_006724352 /// XR_244395 /// XR_244396 0006265 // DNA topological change // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003916 // DNA topoisomerase activity // traceable author statement /// 0003917 // DNA topoisomerase type I activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213661_at AI671186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI671186 /FEA=EST /DB_XREF=gi:4850917 /DB_XREF=est:wb14d04.x1 /CLONE=IMAGE:2305639 /UG=Hs.55044 DKFZP586H2123 protein AI671186 peptidase domain containing associated with muscle regeneration 1 PAMR1 25891 NM_001001991 /// NM_001282675 /// NM_001282676 /// NM_015430 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation 213662_at AI740515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI740515 /FEA=EST /DB_XREF=gi:5108803 /DB_XREF=est:wg16a10.x1 /CLONE=IMAGE:2365242 /UG=Hs.82273 hypothetical protein AI740515 family with sequence similarity 134, member B FAM134B 54463 NM_001034850 /// NM_019000 /// XM_005248312 0019233 // sensory perception of pain // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213663_s_at AI740515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI740515 /FEA=EST /DB_XREF=gi:5108803 /DB_XREF=est:wg16a10.x1 /CLONE=IMAGE:2365242 /UG=Hs.82273 hypothetical protein AI740515 family with sequence similarity 134, member B FAM134B 54463 NM_001034850 /// NM_019000 /// XM_005248312 0019233 // sensory perception of pain // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213664_at AW235061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW235061 /FEA=EST /DB_XREF=gi:6567450 /DB_XREF=est:xn18b08.x1 /CLONE=IMAGE:2694039 /UG=Hs.91139 solute carrier family 1 (neuronalepithelial high affinity glutamate transporter, system Xag), member 1 AW235061 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 SLC1A1 6505 NM_004170 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015501 // glutamate:sodium symporter activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 213665_at AI989477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI989477 /FEA=EST /DB_XREF=gi:5836358 /DB_XREF=est:ws25b11.x1 /CLONE=IMAGE:2498205 /UG=Hs.83484 SRY (sex determining region Y)-box 4 AI989477 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213666_at AK026589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026589.1 /DEF=Homo sapiens cDNA: FLJ22936 fis, clone KAT07936. /FEA=mRNA /DB_XREF=gi:10439473 /UG=Hs.90998 KIAA0128 protein; septin 2 AK026589 septin 6 SEPT6 23157 NM_015129 /// NM_145799 /// NM_145800 /// NM_145802 /// XM_005262400 /// XM_006724748 /// XM_006724749 /// XM_006724750 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement 213667_at AB002307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002307.1 /DEF=Human mRNA for KIAA0309 gene, partial cds. /FEA=mRNA /GEN=KIAA0309 /DB_XREF=gi:2224558 /UG=Hs.87908 Snf2-related CBP activator protein AB002307 uncharacterized LOC100862671 /// Snf2-related CREBBP activator protein LOC100862671 /// SRCAP 10847 /// 100862671 NM_001256829 /// NM_006662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 213668_s_at AI989477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI989477 /FEA=EST /DB_XREF=gi:5836358 /DB_XREF=est:ws25b11.x1 /CLONE=IMAGE:2498205 /UG=Hs.83484 SRY (sex determining region Y)-box 4 AI989477 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213669_at AB006628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006628.1 /DEF=Homo sapiens mRNA for KIAA0290 gene, partial cds. /FEA=mRNA /GEN=KIAA0290 /DB_XREF=gi:2564327 /UG=Hs.96485 KIAA0290 protein AB006628 FCH domain only 1 FCHO1 23149 NM_001161357 /// NM_001161358 /// NM_001161359 /// NM_015122 /// XM_005259831 /// XM_006722701 /// XM_006722702 /// XM_006722703 0006897 // endocytosis // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 213670_x_at AI768378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI768378 /FEA=EST /DB_XREF=gi:5234887 /DB_XREF=est:wg84g03.x1 /CLONE=IMAGE:2371828 /UG=Hs.295112 KIAA0618 gene product AI768378 NOP2/Sun domain family, member 5 pseudogene 1 NSUN5P1 155400 NM_001039575 /// NM_001039576 /// NR_033322 /// NR_104013 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213671_s_at AA621558 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA621558 /FEA=EST /DB_XREF=gi:2525497 /DB_XREF=est:af53a09.s1 /CLONE=IMAGE:1035352 /UG=Hs.279946 methionine-tRNA synthetase AA621558 methionyl-tRNA synthetase /// microRNA 6758 MARS /// MIR6758 4141 /// 102465454 NM_004990 /// NR_106816 /// XM_006719398 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006431 // methionyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004825 // methionine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 213672_at AA621558 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA621558 /FEA=EST /DB_XREF=gi:2525497 /DB_XREF=est:af53a09.s1 /CLONE=IMAGE:1035352 /UG=Hs.279946 methionine-tRNA synthetase AA621558 methionyl-tRNA synthetase /// microRNA 6758 MARS /// MIR6758 4141 /// 102465454 NM_004990 /// NR_106816 /// XM_006719398 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006431 // methionyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004825 // methionine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 213673_x_at AA156251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156251 /FEA=EST /DB_XREF=gi:1727869 /DB_XREF=est:zl50g12.s1 /CLONE=IMAGE:505414 /UG=Hs.109494 secreted protein of unknown function AA156251 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213674_x_at AI858004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI858004 /FEA=EST /DB_XREF=gi:5511620 /DB_XREF=est:wj69b09.x1 /CLONE=IMAGE:2408057 /UG=Hs.284277 Homo sapiens immunoglobulin mu chain antibody MO30 (IgM) mRNA, complete cds AI858004 immunoglobulin heavy constant delta IGHD 3495 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 213675_at W61005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W61005 /FEA=EST /DB_XREF=gi:1367764 /DB_XREF=est:zd29a11.s1 /CLONE=IMAGE:342044 /UG=Hs.14896 DHHC1 protein W61005 parvin, alpha PARVA 55742 NM_018222 /// XM_005253015 0001525 // angiogenesis // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0070252 // actin-mediated cell contraction // inferred from sequence or structural similarity /// 0071670 // smooth muscle cell chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213676_at AL038824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL038824 /FEA=EST /DB_XREF=gi:5407955 /DB_XREF=est:DKFZp566O2446_s1 /CLONE=DKFZp566O2446 /UG=Hs.12840 Homo sapiens germline mRNA sequence AL038824 transmembrane protein 151B TMEM151B 441151 NM_001039704 /// NM_001137560 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213677_s_at BG434893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG434893 /FEA=EST /DB_XREF=gi:13341399 /DB_XREF=est:602507842F1 /CLONE=IMAGE:4604891 /UG=Hs.111749 postmeiotic segregation increased (S. cerevisiae) 1 BG434893 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) PMS1 5378 NM_000534 /// NM_001128143 /// NM_001128144 /// NM_001289408 /// NM_001289409 /// NR_110332 /// XM_005246647 /// XM_005246649 /// XM_006712596 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // /// 0042493 // response to drug // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0032300 // mismatch repair complex // /// 0032389 // MutLalpha complex // not recorded 0003677 // DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // 213678_at F09448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:F09448 /FEA=EST /DB_XREF=gi:681981 /DB_XREF=est:HSC31G032 /CLONE=c-31g03 /UG=Hs.12840 Homo sapiens germline mRNA sequence F09448 transmembrane protein 151B TMEM151B 441151 NM_001039704 /// NM_001137560 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213679_at AL049329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049329.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G196 (from clone DKFZp564G196); partial cds. /FEA=mRNA /GEN=DKFZp564G196 /PROD=hypothetical protein /DB_XREF=gi:4500104 /UG=Hs.128384 DKFZP564G196 protein AL049329 tetratricopeptide repeat domain 30A TTC30A 92104 NM_152275 0030030 // cell projection organization // inferred from electronic annotation 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213680_at AI831452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI831452 /FEA=EST /DB_XREF=gi:5452123 /DB_XREF=est:wj49b03.x1 /CLONE=IMAGE:2406125 /UG=Hs.111758 keratin 6A AI831452 keratin 6B KRT6B 3854 NM_005555 0007398 // ectoderm development // traceable author statement 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement 213681_at AW512817 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW512817 /FEA=EST /DB_XREF=gi:7150895 /DB_XREF=est:xm04d03.x1 /CLONE=IMAGE:2683205 /UG=Hs.173884 cysteine and histidine rich protein AW512817 cysteine/histidine-rich 1 CYHR1 50626 NM_001129888 /// NM_032687 /// NM_138496 /// XM_006716560 /// XM_006716561 /// XM_006716562 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213682_at AL036344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL036344 /FEA=EST /DB_XREF=gi:5927743 /DB_XREF=est:DKFZp564A053_r1 /CLONE=DKFZp564A053 /UG=Hs.169329 DKFZP564A043 protein AL036344 nucleoporin 50kDa NUP50 10762 NM_007172 /// NM_153645 /// XM_005261312 /// XM_005261313 /// XM_005261314 /// XM_006724103 /// XM_006724104 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213683_at AV727634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV727634 /FEA=EST /DB_XREF=gi:10837055 /DB_XREF=est:AV727634 /CLONE=HTCAYH08 /UG=Hs.14945 long fatty acyl-CoA synthetase 2 gene AV727634 acyl-CoA synthetase long-chain family member 6 ACSL6 23305 NM_001009185 /// NM_001205247 /// NM_001205248 /// NM_001205250 /// NM_001205251 /// NM_015256 /// XM_006714579 /// XM_006714580 /// XM_006714581 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // non-traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010747 // positive regulation of plasma membrane long-chain fatty acid transport // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 213684_s_at BF671400 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF671400 /FEA=EST /DB_XREF=gi:11945307 /DB_XREF=est:602151296F1 /CLONE=IMAGE:4292591 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) BF671400 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213685_at AA830143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA830143 /FEA=EST /DB_XREF=gi:2903242 /DB_XREF=est:oc44e11.s1 /CLONE=IMAGE:1352588 /UG=Hs.15535 Homo sapiens clone 24582 mRNA sequence AA830143 TCEB3 antisense RNA 1 TCEB3-AS1 100506963 NR_038280 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 213686_at AI186145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186145 /FEA=EST /DB_XREF=gi:3736783 /DB_XREF=est:qe46a06.x1 /CLONE=IMAGE:1742002 /UG=Hs.154336 Homo sapiens clone 24583 mRNA sequence AI186145 vacuolar protein sorting 13 homolog A (S. cerevisiae) VPS13A 23230 NM_001018037 /// NM_001018038 /// NM_015186 /// NM_033305 /// XR_242579 /// XR_242580 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008104 // protein localization // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0031045 // dense core granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213687_s_at BE968801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE968801 /FEA=EST /DB_XREF=gi:10579506 /DB_XREF=est:601649806F1 /CLONE=IMAGE:3933816 /UG=Hs.179666 uncharacterized hypothalamus protein HSMNP1 BE968801 ribosomal protein L35a RPL35A 6165 NM_000996 /// XM_005269350 /// XM_005269351 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213688_at N25325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25325 /FEA=EST /DB_XREF=gi:1139475 /DB_XREF=est:yx55b03.s1 /CLONE=IMAGE:265613 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) N25325 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 213689_x_at AL137958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137958 /FEA=EST /DB_XREF=gi:6854638 /DB_XREF=est:DKFZp761C1715_r1 /CLONE=DKFZp761C1715 /UG=Hs.180946 ribosomal protein L5 AL137958 family with sequence similarity 69, member A FAM69A 388650 NM_001006605 /// NM_001252269 /// NM_001252270 /// NM_001252271 /// NM_001252273 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213690_s_at AL050131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050131.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I111 (from clone DKFZp586I111); partial cds. /FEA=mRNA /GEN=DKFZp586I111 /PROD=hypothetical protein /DB_XREF=gi:4884338 /UG=Hs.227429 DKFZP586I111 protein AL050131 uncharacterized LOC101928378 LOC101928378 101928378 NR_110730 /// XR_244005 /// XR_248576 /// XR_253899 213691_at AL050131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050131.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I111 (from clone DKFZp586I111); partial cds. /FEA=mRNA /GEN=DKFZp586I111 /PROD=hypothetical protein /DB_XREF=gi:4884338 /UG=Hs.227429 DKFZP586I111 protein AL050131 uncharacterized LOC101928378 LOC101928378 101928378 NR_110730 /// XR_244005 /// XR_248576 /// XR_253899 213692_s_at AA904259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA904259 /FEA=EST /DB_XREF=gi:3039382 /DB_XREF=est:oe74h05.s1 /CLONE=IMAGE:1417401 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor AA904259 vitamin D (1,25- dihydroxyvitamin D3) receptor VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 213693_s_at AI610869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI610869 /FEA=EST /DB_XREF=gi:4620036 /DB_XREF=est:tp21e08.x1 /CLONE=IMAGE:2188454 /UG=Hs.89603 mucin 1, transmembrane AI610869 mucin 1, cell surface associated MUC1 4582 NM_001018016 /// NM_001018017 /// NM_001018021 /// NM_001044390 /// NM_001044391 /// NM_001044392 /// NM_001044393 /// NM_001204285 /// NM_001204286 /// NM_001204287 /// NM_001204288 /// NM_001204289 /// NM_001204290 /// NM_001204291 /// NM_001204292 /// NM_001204293 /// NM_001204294 /// NM_001204295 /// NM_001204296 /// NM_001204297 /// NM_002456 /// NM_182741 0001666 // response to hypoxia // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016266 // O-glycan processing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043618 // regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090240 // positive regulation of histone H4 acetylation // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213694_at AW027347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027347 /FEA=EST /DB_XREF=gi:5886103 /DB_XREF=est:wt73e07.x1 /CLONE=IMAGE:2513124 /UG=Hs.3623 hypothetical protein FLJ11220 AW027347 round spermatid basic protein 1 RSBN1 54665 NM_018364 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213695_at L48516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L48516.1 /DEF=Homo sapiens paraoxonase 3 (PON3) mRNA, 3 end of cds. /FEA=mRNA /GEN=PON3 /PROD=paraoxonase-3 /DB_XREF=gi:1333633 /UG=Hs.296259 paraoxonase 3 L48516 paraoxonase 3 PON3 5446 NM_000940 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009605 // response to external stimulus // non-traceable author statement /// 0010124 // phenylacetate catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay /// 0046226 // coumarin catabolic process // inferred from electronic annotation /// 0046395 // carboxylic acid catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004063 // aryldialkylphosphatase activity // inferred from electronic annotation /// 0004064 // arylesterase activity // inferred from direct assay /// 0004064 // arylesterase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016844 // strictosidine synthase activity // inferred from electronic annotation /// 0018733 // 3,4-dihydrocoumarin hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047856 // dihydrocoumarin hydrolase activity // inferred from electronic annotation 213696_s_at AA421957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA421957 /FEA=EST /DB_XREF=gi:2100773 /DB_XREF=est:zv30f09.r1 /CLONE=IMAGE:755177 /UG=Hs.301756 ESTs, Weakly similar to T31475 hypothetical protein Y62F5A.1b - Caenorhabditis elegans C.elegans AA421957 mediator complex subunit 8 MED8 112950 NM_001001653 /// NM_052877 /// NM_201542 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213697_at AW291829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW291829 /FEA=EST /DB_XREF=gi:6698465 /DB_XREF=est:UI-H-BI2-agl-e-11-0-UI.s1 /CLONE=IMAGE:2724597 /UG=Hs.30148 homeodomain-interacting protein kinase 3 AW291829 homeodomain interacting protein kinase 3 HIPK3 10114 NM_001048200 /// NM_001278162 /// NM_001278163 /// NM_005734 /// XM_005252729 /// XM_006718120 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009299 // mRNA transcription // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation 213698_at AI805560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI805560 /FEA=EST /DB_XREF=gi:5392126 /DB_XREF=est:tx86f04.x1 /CLONE=IMAGE:2276479 /UG=Hs.301637 zinc finger protein 258 AI805560 zinc finger, MYM-type 6 /// ZMYM6 neighbor ZMYM6 /// ZMYM6NB 9204 /// 100506144 NM_001195156 /// NM_007167 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213699_s_at AA854017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA854017 /FEA=EST /DB_XREF=gi:2941555 /DB_XREF=est:aj52d02.s1 /CLONE=IMAGE:1393923 /UG=Hs.74405 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide AA854017 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta YWHAQ 10971 NM_006826 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 213700_s_at AA554945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA554945 /FEA=EST /DB_XREF=gi:2325484 /DB_XREF=est:ni36d11.s1 /CLONE=IMAGE:978933 /UG=Hs.8173 hypothetical protein FLJ10803 AA554945 pyruvate kinase, muscle PKM 5315 NM_001206796 /// NM_001206797 /// NM_001206798 /// NM_001206799 /// NM_002654 /// NM_182470 /// NM_182471 /// XM_005254443 /// XM_005254445 /// XM_006720570 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213701_at AW299245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299245 /FEA=EST /DB_XREF=gi:6708922 /DB_XREF=est:xs48d07.x1 /CLONE=IMAGE:2772877 /UG=Hs.62601 Homo sapiens mRNA; cDNA DKFZp586K1318 (from clone DKFZp586K1318) AW299245 chromosome 12 open reading frame 29 C12orf29 91298 NM_001009894 213702_x_at AI934569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI934569 /FEA=EST /DB_XREF=gi:5673366 /DB_XREF=est:wp09e10.x1 /CLONE=IMAGE:2464362 /UG=Hs.75811 N-acylsphingosine amidohydrolase (acid ceramidase) AI934569 N-acylsphingosine amidohydrolase (acid ceramidase) 1 ASAH1 427 NM_001127505 /// NM_004315 /// NM_177924 /// XM_005273504 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017040 // ceramidase activity // traceable author statement 213703_at W95043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W95043 /FEA=EST /DB_XREF=gi:1424182 /DB_XREF=est:zh46c11.s1 /CLONE=IMAGE:415124 /UG=Hs.79732 fibulin 1 W95043 long intergenic non-protein coding RNA 342 LINC00342 150759 NR_103734 213704_at AA129753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129753 /FEA=EST /DB_XREF=gi:1690163 /DB_XREF=est:zl16a12.s1 /CLONE=IMAGE:502078 /UG=Hs.78948 Rab geranylgeranyltransferase, beta subunit AA129753 Rab geranylgeranyltransferase, beta subunit /// small nucleolar RNA, C/D box 45A /// small nucleolar RNA, C/D box 45B /// small nucleolar RNA, C/D box 45C RABGGTB /// SNORD45A /// SNORD45B /// SNORD45C 5876 /// 26804 /// 26805 /// 692085 NM_004582 /// NR_002748 /// NR_002749 /// NR_003042 /// NR_073562 0006464 // cellular protein modification process // non-traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213705_at AW301861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301861 /FEA=EST /DB_XREF=gi:6711538 /DB_XREF=est:xr84d04.x1 /CLONE=IMAGE:2766823 /UG=Hs.77502 methionine adenosyltransferase II, alpha AW301861 gamma-glutamyl carboxylase GGCX 2677 NM_000821 /// NM_001142269 /// XM_005264259 0006464 // cellular protein modification process // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008488 // gamma-glutamyl carboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 213706_at AI368018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI368018 /FEA=EST /DB_XREF=gi:4137763 /DB_XREF=est:qq39h02.x1 /CLONE=IMAGE:1934931 /UG=Hs.9739 glycerol-3-phosphate dehydrogenase 1 (soluble) AI368018 glycerol-3-phosphate dehydrogenase 1 (soluble) GPD1 2819 NM_001257199 /// NM_005276 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006116 // NADH oxidation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046168 // glycerol-3-phosphate catabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009331 // glycerol-3-phosphate dehydrogenase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004367 // glycerol-3-phosphate dehydrogenase [NAD+] activity // inferred from electronic annotation /// 0004368 // glycerol-3-phosphate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 213707_s_at NM_005221 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005221.3 /DEF=Homo sapiens distal-less homeo box 5 (DLX5), mRNA. /FEA=CDS /GEN=DLX5 /PROD=distal-less homeo box 5 /DB_XREF=gi:6224974 /UG=Hs.99348 distal-less homeo box 5 /FL=gb:NM_005221.3 NM_005221 distal-less homeobox 5 DLX5 1749 NM_005221 /// XM_005250185 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043583 // ear development // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 213708_s_at N40555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N40555 /FEA=EST /DB_XREF=gi:1164152 /DB_XREF=est:yy48f08.s1 /CLONE=IMAGE:276807 /UG=Hs.279032 GT198, complete ORF N40555 MLX, MAX dimerization protein MLX 6945 NM_170607 /// NM_198204 /// NM_198205 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 213709_at H11725 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H11725 /FEA=EST /DB_XREF=gi:876545 /DB_XREF=est:ym11c07.s1 /CLONE=IMAGE:47686 /UG=Hs.4276 KIAA1701 protein H11725 basic helix-loop-helix domain containing, class B, 9 BHLHB9 80823 NM_001142524 /// NM_001142525 /// NM_001142526 /// NM_001142527 /// NM_001142528 /// NM_001142529 /// NM_001142530 /// NM_030639 0007611 // learning or memory // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 213710_s_at AL523275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523275 /FEA=EST /DB_XREF=gi:12786768 /DB_XREF=est:AL523275 /CLONE=CS0DC001YL12 (5 prime) /UG=Hs.279009 matrix Gla protein AL523275 calmodulin 1 (phosphorylase kinase, delta) CALM1 801 NM_001166106 /// NM_006888 /// XM_006720258 213711_at NM_002281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002281.1 /DEF=Homo sapiens keratin, hair, basic, 1 (KRTHB1), mRNA. /FEA=CDS /GEN=KRTHB1 /PROD=keratin, hair, basic, 1 /DB_XREF=gi:4504930 /UG=Hs.32952 keratin, hair, basic, 1 /FL=gb:NM_002281.1 NM_002281 keratin 81 KRT81 3887 NM_002281 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213712_at BF508639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508639 /FEA=EST /DB_XREF=gi:11591937 /DB_XREF=est:UI-H-BI4-aop-a-07-0-UI.s1 /CLONE=IMAGE:3085357 /UG=Hs.30504 Homo sapiens mRNA; cDNA DKFZp434E082 (from clone DKFZp434E082) BF508639 ELOVL fatty acid elongase 2 ELOVL2 54898 NM_017770 /// XM_005249200 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034626 // fatty acid elongation, polyunsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 213713_s_at R48779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R48779 /FEA=EST /DB_XREF=gi:810805 /DB_XREF=est:yj69c07.s1 /CLONE=IMAGE:153996 /UG=Hs.293845 ESTs, Weakly similar to B32688 beta-galactosidase-related protein H.sapiens R48779 galactosidase, beta 1-like 2 GLB1L2 89944 NM_138342 /// XM_006718937 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009341 // beta-galactosidase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 213714_at AI040163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040163 /FEA=EST /DB_XREF=gi:3279357 /DB_XREF=est:ox42c02.s1 /CLONE=IMAGE:1658978 /UG=Hs.30941 calcium channel, voltage-dependent, beta 2 subunit /FL=gb:AF137376.1 AI040163 calcium channel, voltage-dependent, beta 2 subunit CACNB2 783 NM_000724 /// NM_001167945 /// NM_201570 /// NM_201571 /// NM_201572 /// NM_201590 /// NM_201593 /// NM_201596 /// NM_201597 /// XM_005252588 /// XM_005252591 /// XM_006717502 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay 213715_s_at AF070591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070591.1 /DEF=Homo sapiens clone 24649 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387966 /UG=Hs.322473 Homo sapiens clone 24649 mRNA sequence AF070591 KN motif and ankyrin repeat domains 3 KANK3 256949 NM_198471 /// XM_005272467 /// XM_006722718 0005515 // protein binding // inferred from electronic annotation 213716_s_at BF939675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939675 /FEA=EST /DB_XREF=gi:12357086 /DB_XREF=est:nac79g07.x1 /CLONE=IMAGE:3440820 /UG=Hs.326612 Homo sapiens secreted and transmembrane 1 (SECTM1), mRNA BF939675 secreted and transmembrane 1 SECTM1 6398 NM_003004 /// XM_005256392 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007498 // mesoderm development // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005125 // cytokine activity // traceable author statement 213717_at AA211481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA211481 /FEA=EST /DB_XREF=gi:1810135 /DB_XREF=est:zn55b10.s1 /CLONE=IMAGE:562075 /UG=Hs.49998 Z-band alternatively spliced PDZ-motif AA211481 LIM domain binding 3 LDB3 11155 NM_001080114 /// NM_001080115 /// NM_001080116 /// NM_001171610 /// NM_001171611 /// NM_007078 /// XM_005269464 /// XM_005269465 /// XM_005269466 /// XM_005269467 /// XM_005269468 /// XM_006717598 /// XM_006717599 /// XM_006717600 /// XM_006717601 0045214 // sarcomere organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation 213718_at BE222257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222257 /FEA=EST /DB_XREF=gi:8909575 /DB_XREF=est:hu09g03.x1 /CLONE=IMAGE:3166132 /UG=Hs.49994 Homo sapiens, clone MGC:10871, mRNA, complete cds BE222257 RBM14-RBM4 readthrough /// RNA binding motif protein 4 RBM14-RBM4 /// RBM4 5936 /// 100526737 NM_001198843 /// NM_001198844 /// NM_001198845 /// NM_001198846 /// NM_002896 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0002190 // cap-independent translational initiation // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0032055 // negative regulation of translation in response to stress // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0045947 // negative regulation of translational initiation // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097157 // pre-mRNA intronic binding // inferred from direct assay /// 0097158 // pre-mRNA intronic pyrimidine-rich binding // inferred from direct assay 213719_s_at AI831675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI831675 /FEA=EST /DB_XREF=gi:5452346 /DB_XREF=est:wj50g03.x1 /CLONE=IMAGE:2406292 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AI831675 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 213720_s_at AI831675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI831675 /FEA=EST /DB_XREF=gi:5452346 /DB_XREF=est:wj50g03.x1 /CLONE=IMAGE:2406292 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AI831675 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 213721_at L07335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L07335.1 /DEF=Homo sapiens (clone 6AR33) HMG box mRNA, 3 end cds. /FEA=mRNA /DB_XREF=gi:184239 /UG=Hs.816 SRY (sex determining region Y)-box 2 L07335 SRY (sex determining region Y)-box 2 SOX2 6657 NM_003106 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001654 // eye development // inferred from expression pattern /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001714 // endodermal cell fate specification // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021781 // glial cell fate commitment // non-traceable author statement /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from expression pattern /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from expression pattern /// 0030910 // olfactory placode formation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0042221 // response to chemical // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046148 // pigment biosynthetic process // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048839 // inner ear development // inferred from expression pattern /// 0048852 // diencephalon morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0050973 // detection of mechanical stimulus involved in equilibrioception // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213722_at AW007161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007161 /FEA=EST /DB_XREF=gi:5855939 /DB_XREF=est:ws50a01.x1 /CLONE=IMAGE:2500584 /UG=Hs.816 SRY (sex determining region Y)-box 2 AW007161 SRY (sex determining region Y)-box 2 SOX2 6657 NM_003106 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001654 // eye development // inferred from expression pattern /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001714 // endodermal cell fate specification // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021781 // glial cell fate commitment // non-traceable author statement /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from expression pattern /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from expression pattern /// 0030910 // olfactory placode formation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0042221 // response to chemical // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046148 // pigment biosynthetic process // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048839 // inner ear development // inferred from expression pattern /// 0048852 // diencephalon morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0050973 // detection of mechanical stimulus involved in equilibrioception // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213723_s_at AI424441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI424441 /FEA=EST /DB_XREF=gi:4270372 /DB_XREF=est:te90h07.x1 /CLONE=IMAGE:2094013 /UG=Hs.89560 iduronidase, alpha-L- AI424441 iduronidase, alpha-L- IDUA 3425 NM_000203 /// NR_110313 /// XM_006713881 /// XM_006713882 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005984 // disaccharide metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030209 // dermatan sulfate catabolic process // inferred from direct assay /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048878 // chemical homeostasis // inferred from electronic annotation 0030135 // coated vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003940 // L-iduronidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation 213724_s_at AI870615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI870615 /FEA=EST /DB_XREF=gi:5544583 /DB_XREF=est:wl75e10.x1 /CLONE=IMAGE:2430762 /UG=Hs.92261 pyruvate dehydrogenase kinase, isoenzyme 2 AI870615 pyruvate dehydrogenase kinase, isozyme 2 PDK2 5164 NM_001199898 /// NM_001199899 /// NM_001199900 /// NM_002611 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006111 // regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010565 // regulation of cellular ketone metabolic process // inferred from sequence or structural similarity /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031670 // cellular response to nutrient // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 213725_x_at AI693140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI693140 /FEA=EST /DB_XREF=gi:4970480 /DB_XREF=est:wd68a05.x1 /CLONE=IMAGE:2336720 /UG=Hs.22907 Homo sapiens mRNA; cDNA DKFZp586F071 (from clone DKFZp586F071) AI693140 xylosyltransferase I XYLT1 64131 NM_022166 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030158 // protein xylosyltransferase activity // traceable author statement 213726_x_at AA515698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA515698 /FEA=EST /DB_XREF=gi:2255298 /DB_XREF=est:nf66f09.s1 /CLONE=IMAGE:924905 /UG=Hs.251653 tubulin, beta, 2 AA515698 tubulin, beta 4B class IVb TUBB4B 10383 NM_006088 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 213727_x_at AI743654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743654 /FEA=EST /DB_XREF=gi:5111942 /DB_XREF=est:wg41d01.x1 /CLONE=IMAGE:2367649 /UG=Hs.154145 hypothetical protein FLJ11585 AI743654 metallophosphoesterase 1 MPPE1 65258 NM_001242904 /// NM_023075 /// NM_138608 /// NR_040241 /// NR_040242 /// NR_040243 /// XM_006722340 /// XM_006722341 /// XM_006722342 /// XM_006722343 /// XM_006722344 /// XM_006722345 /// XM_006722346 /// XM_006722347 /// XM_006722348 /// XM_006722349 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from sequence or structural similarity 0008081 // phosphoric diester hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 213728_at AI248598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI248598 /FEA=EST /DB_XREF=gi:3843995 /DB_XREF=est:qh71h03.x1 /CLONE=IMAGE:1850165 /UG=Hs.150101 lysosomal-associated membrane protein 1 AI248598 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 213729_at Z78308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z78308 /FEA=EST /DB_XREF=gi:1495081 /DB_XREF=est:HSZ78308 /CLONE=1.47 (CEPH) /UG=Hs.119325 Huntingtin-interacting protein A Z78308 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) PRPF40A 55660 NM_017892 /// XM_005246676 /// XM_005246677 /// XM_005246678 /// XM_005246679 0006397 // mRNA processing // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 213730_x_at BE962186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE962186 /FEA=EST /DB_XREF=gi:11764831 /DB_XREF=est:601655401R1 /CLONE=IMAGE:3846024 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) BE962186 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 213731_s_at AI871234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871234 /FEA=EST /DB_XREF=gi:5545202 /DB_XREF=est:wl80c06.x1 /CLONE=IMAGE:2431210 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) AI871234 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 213732_at AI871234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871234 /FEA=EST /DB_XREF=gi:5545202 /DB_XREF=est:wl80c06.x1 /CLONE=IMAGE:2431210 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) AI871234 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 213733_at BF740152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF740152 /FEA=EST /DB_XREF=gi:12066828 /DB_XREF=est:7n13g08.x1 /CLONE=IMAGE:3564495 /UG=Hs.121555 myosin IE BF740152 myosin IF MYO1F 4542 NM_012335 /// XM_005272475 /// XM_005272476 /// XM_005272477 /// XR_430140 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // non-traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 213734_at BG260658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG260658 /FEA=EST /DB_XREF=gi:12770474 /DB_XREF=est:602372225F1 /CLONE=IMAGE:4480039 /UG=Hs.136644 CS box-containing WD protein BG260658 replication factor C (activator 1) 5, 36.5kDa RFC5 5985 NM_001130112 /// NM_001130113 /// NM_001206801 /// NM_007370 /// NM_181578 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 213735_s_at AI557312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI557312 /FEA=EST /DB_XREF=gi:4489675 /DB_XREF=est:PT2.1_16_E11.r /UG=Hs.1342 cytochrome c oxidase subunit Vb AI557312 cytochrome c oxidase subunit Vb COX5B 1329 NM_001862 0007585 // respiratory gaseous exchange // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213736_at AI557312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI557312 /FEA=EST /DB_XREF=gi:4489675 /DB_XREF=est:PT2.1_16_E11.r /UG=Hs.1342 cytochrome c oxidase subunit Vb AI557312 cytochrome c oxidase subunit Vb COX5B 1329 NM_001862 0007585 // respiratory gaseous exchange // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213737_x_at AI620911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI620911 /FEA=EST /DB_XREF=gi:4630037 /DB_XREF=est:tu05d12.x1 /CLONE=IMAGE:2250167 /UG=Hs.205125 ESTs AI620911 golgin A8 family, member N GOLGA8N 643699 NM_001282494 /// XM_006720633 /// XM_006725548 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213738_s_at AI587323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI587323 /FEA=EST /DB_XREF=gi:4573764 /DB_XREF=est:tq04h04.x1 /CLONE=IMAGE:2207863 /UG=Hs.155101 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle AI587323 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle ATP5A1 498 NM_001001935 /// NM_001001937 /// NM_001257334 /// NM_001257335 /// NM_004046 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006754 // ATP biosynthetic process // inferred by curator /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 213739_at AL049387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049387.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N1918 (from clone DKFZp586N1918). /FEA=mRNA /DB_XREF=gi:4500178 /UG=Hs.169936 Homo sapiens mRNA; cDNA DKFZp586N1918 (from clone DKFZp586N1918) AL049387 uncharacterized LOC103344931 LOC103344931 103344931 NR_120684 213740_s_at AI401287 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI401287 /FEA=EST /DB_XREF=gi:4244374 /DB_XREF=est:tg92b04.x1 /CLONE=IMAGE:2116207 /UG=Hs.155165 zinc finger protein-like 1 AI401287 transmembrane protein 262 TMEM262 100130348 NM_001242631 /// NM_001282448 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213741_s_at BF575685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF575685 /FEA=EST /DB_XREF=gi:11649397 /DB_XREF=est:602135301F1 /CLONE=IMAGE:4290312 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) BF575685 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 213742_at AW241752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW241752 /FEA=EST /DB_XREF=gi:6575506 /DB_XREF=est:xn74f04.x1 /CLONE=IMAGE:2700223 /UG=Hs.160726 Homo sapiens cDNA FLJ11680 fis, clone HEMBA1004820 AW241752 serine/arginine-rich splicing factor 11 SRSF11 9295 NM_001190987 /// NM_004768 /// XM_005271338 /// XM_005271339 /// XM_006711037 /// XM_006711038 /// XM_006711039 /// XM_006711040 /// XM_006711041 /// XR_426640 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213743_at BE674119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674119 /FEA=EST /DB_XREF=gi:10034660 /DB_XREF=est:7d75b03.x1 /CLONE=IMAGE:3278765 /UG=Hs.155478 cyclin T2 BE674119 cyclin T2 CCNT2 905 NM_001241 /// NM_058241 /// NR_037649 /// XM_005263830 /// XM_005263831 /// XM_005263832 /// XM_006712827 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0019901 // protein kinase binding // inferred from electronic annotation 213744_at AI817331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817331 /FEA=EST /DB_XREF=gi:5436410 /DB_XREF=est:wk36h03.x1 /CLONE=IMAGE:2417525 /UG=Hs.196012 KIAA0534 protein AI817331 attractin-like 1 ATRNL1 26033 NM_001276282 /// NM_207303 /// NR_074088 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 213745_at AW151108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW151108 /FEA=EST /DB_XREF=gi:6199006 /DB_XREF=est:xg33d03.x1 /CLONE=IMAGE:2629349 /UG=Hs.196012 KIAA0534 protein AW151108 attractin-like 1 ATRNL1 26033 NM_001276282 /// NM_207303 /// NR_074088 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 213746_s_at AW051856 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW051856 /FEA=EST /DB_XREF=gi:5914215 /DB_XREF=est:wz04a05.x1 /CLONE=IMAGE:2557040 /UG=Hs.195464 filamin A, alpha (actin-binding protein-280) AW051856 filamin A, alpha FLNA 2316 NM_001110556 /// NM_001456 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from direct assay /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred by curator /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097440 // apical dendrite // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from direct assay /// 0031267 // small GTPase binding // inferred from direct assay /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 213747_at AA047234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA047234 /FEA=EST /DB_XREF=gi:1525134 /DB_XREF=est:zf50b09.s1 /CLONE=IMAGE:380345 /UG=Hs.223014 antizyme inhibitor AA047234 213748_at AW271713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW271713 /FEA=EST /DB_XREF=gi:6658743 /DB_XREF=est:xs17f10.x1 /CLONE=IMAGE:2769931 /UG=Hs.21560 KIAA0298 gene product AW271713 tripartite motif containing 66 TRIM66 9866 NM_014818 /// XM_006718397 /// XM_006718398 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213749_at AV686235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV686235 /FEA=EST /DB_XREF=gi:10288098 /DB_XREF=est:AV686235 /CLONE=GKCCLD02 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) AV686235 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) MASP1 5648 NM_001031849 /// NM_001879 /// NM_139125 /// NR_033519 /// XM_006713700 /// XM_006713701 0001867 // complement activation, lectin pathway // inferred from mutant phenotype /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 213750_at AA928506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA928506 /FEA=EST /DB_XREF=gi:3076797 /DB_XREF=est:om17g03.s1 /CLONE=IMAGE:1541332 /UG=Hs.10762 ESTs AA928506 ribosomal L1 domain containing 1 RSL1D1 26156 NM_015659 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213751_at AW873594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW873594 /FEA=EST /DB_XREF=gi:8007647 /DB_XREF=est:ho62g07.x1 /CLONE=IMAGE:3042012 /UG=Hs.31809 hypothetical protein AW873594 protein phosphatase 1, regulatory subunit 37 PPP1R37 284352 NM_019121 /// XM_006723159 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 213752_at BF111846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF111846 /FEA=EST /DB_XREF=gi:10941536 /DB_XREF=est:7l36d01.x1 /CLONE=IMAGE:3523608 /UG=Hs.106334 Homo sapiens clone 23836 mRNA sequence BF111846 kazrin, periplakin interacting protein KAZN 23254 NM_001017999 /// NM_001018000 /// NM_001018001 /// NM_015209 /// NM_201628 /// XM_005245795 /// XM_005245796 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 213753_x_at BF541557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF541557 /FEA=EST /DB_XREF=gi:11628938 /DB_XREF=est:602067933F1 /CLONE=IMAGE:4066833 /UG=Hs.119140 eukaryotic translation initiation factor 5A BF541557 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_005256509 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from sequence or structural similarity /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 213754_s_at AW613203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW613203 /FEA=EST /DB_XREF=gi:7318389 /DB_XREF=est:hh67h11.x1 /CLONE=IMAGE:2967909 /UG=Hs.109643 polyadenylate binding protein-interacting protein 1 AW613203 poly(A) binding protein interacting protein 1 PAIP1 10605 NM_006451 /// NM_182789 /// NM_183323 /// XM_005248230 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 213755_s_at BF431501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431501 /FEA=EST /DB_XREF=gi:11443615 /DB_XREF=est:7o14g10.x1 /CLONE=IMAGE:3574099 /UG=Hs.2969 v-ski avian sarcoma viral oncogene homolog BF431501 213756_s_at AI393937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI393937 /FEA=EST /DB_XREF=gi:4223484 /DB_XREF=est:tg11a08.x1 /CLONE=IMAGE:2108438 /UG=Hs.1499 heat shock transcription factor 1 AI393937 heat shock transcription factor 1 HSF1 3297 NM_005526 /// XM_005272315 /// XM_005272316 /// XM_005272317 /// XR_246618 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0090231 // regulation of spindle checkpoint // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001162 // RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213757_at AA393940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA393940 /FEA=EST /DB_XREF=gi:2046909 /DB_XREF=est:zv64f10.r1 /CLONE=IMAGE:758443 /UG=Hs.119140 eukaryotic translation initiation factor 5A AA393940 213758_at AW337510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW337510 /FEA=EST /DB_XREF=gi:6834136 /DB_XREF=est:xx58e02.x1 /CLONE=IMAGE:2847866 /UG=Hs.113205 cytochrome c oxidase subunit IV AW337510 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 /// XM_005255798 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213759_at N74140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N74140 /FEA=EST /DB_XREF=gi:1231425 /DB_XREF=est:za76a05.s1 /CLONE=IMAGE:298448 /UG=Hs.111554 ADP-ribosylation factor-like 7 N74140 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 213760_s_at H82458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H82458 /FEA=EST /DB_XREF=gi:1060547 /DB_XREF=est:yv80b07.r1 /CLONE=IMAGE:249013 /UG=Hs.120766 nucleolar cysteine-rich protein H82458 zinc finger protein 330 ZNF330 27309 NM_001292002 /// NM_014487 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement 213761_at AW664850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW664850 /FEA=EST /DB_XREF=gi:7457394 /DB_XREF=est:hj09f02.x1 /CLONE=IMAGE:2981307 /UG=Hs.12871 hypothetical protein AW664850 Mdm1 nuclear protein homolog (mouse) MDM1 56890 NM_001205028 /// NM_001205029 /// NM_017440 /// NM_020128 /// XM_005269026 /// XM_005269027 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 213762_x_at AI452524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI452524 /FEA=EST /DB_XREF=gi:4285955 /DB_XREF=est:tj62f01.x1 /CLONE=IMAGE:2146105 /UG=Hs.146381 RNA binding motif protein, X chromosome AI452524 uncharacterized LOC101928747 /// RNA binding motif protein, X-linked /// small nucleolar RNA, C/D box 61 LOC101928747 /// RBMX /// SNORD61 26787 /// 27316 /// 101928747 NM_001164803 /// NM_002139 /// NR_002735 /// NR_028476 /// NR_028477 /// XR_244543 /// XR_254186 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // non-traceable author statement /// 0044530 // supraspliceosomal complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213763_at R37104 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R37104 /FEA=EST /DB_XREF=gi:794560 /DB_XREF=est:yf53e12.s1 /CLONE=IMAGE:25731 /UG=Hs.13417 Homo sapiens clone 24670 mRNA sequence R37104 homeodomain interacting protein kinase 2 HIPK2 28996 NM_001113239 /// NM_022740 /// XM_006715934 /// XM_006715935 /// XM_006715936 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001654 // eye development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // non-traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0030578 // PML body organization // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // traceable author statement /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0061072 // iris morphogenesis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0016604 // nuclear body // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0046790 // virion binding // inferred from physical interaction 213764_s_at AW665892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW665892 /FEA=EST /DB_XREF=gi:7458441 /DB_XREF=est:hi95d02.x1 /CLONE=IMAGE:2980035 /UG=Hs.139033 paternally expressed 3 AW665892 microfibrillar associated protein 5 MFAP5 8076 NM_003480 /// XM_005253485 /// XM_006719154 /// XR_242903 /// XR_242904 0030198 // extracellular matrix organization // traceable author statement /// 0043206 // extracellular fibril organization // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement 213765_at AW665892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW665892 /FEA=EST /DB_XREF=gi:7458441 /DB_XREF=est:hi95d02.x1 /CLONE=IMAGE:2980035 /UG=Hs.139033 paternally expressed 3 AW665892 microfibrillar associated protein 5 MFAP5 8076 NM_003480 /// XM_005253485 /// XM_006719154 /// XR_242903 /// XR_242904 0030198 // extracellular matrix organization // traceable author statement /// 0043206 // extracellular fibril organization // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement 213766_x_at N36926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36926 /FEA=EST /DB_XREF=gi:1158068 /DB_XREF=est:yy38e04.s1 /CLONE=IMAGE:273534 /UG=Hs.296361 potassium inwardly-rectifying channel,subfamily J, member 13 N36926 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 213767_at U43586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U43586.1 /DEF=Human kinase suppressor of ras-1 (KSR1) mRNA, partial cds. /FEA=mRNA /GEN=KSR1 /DB_XREF=gi:1171247 /UG=Hs.152094 kinase suppressor of ras U43586 kinase suppressor of ras 1 KSR1 8844 NM_014238 /// XM_006722151 /// XM_006722152 /// XM_006722153 /// XM_006722154 /// XM_006722155 /// XM_006722156 /// XM_006722157 /// XM_006722158 /// XM_006722159 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005078 // MAP-kinase scaffold activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213768_s_at AW950513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW950513 /FEA=EST /DB_XREF=gi:8140168 /DB_XREF=est:EST362583 /UG=Hs.1619 achaete-scute complex (Drosophila) homolog-like 1 AW950513 achaete-scute family bHLH transcription factor 1 ASCL1 429 NM_004316 0001764 // neuron migration // inferred from electronic annotation /// 0003358 // noradrenergic neuron development // inferred from sequence or structural similarity /// 0003359 // noradrenergic neuron fate commitment // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007400 // neuroblast fate determination // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021779 // oligodendrocyte cell fate commitment // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from expression pattern /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // non-traceable author statement /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060163 // subpallium neuron fate commitment // inferred from electronic annotation /// 0060165 // regulation of timing of subpallium neuron differentiation // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // non-traceable author statement /// 0060579 // ventral spinal cord interneuron fate commitment // inferred from sequence or structural similarity /// 0061100 // lung neuroendocrine cell differentiation // inferred from electronic annotation /// 0061102 // stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061103 // carotid body glomus cell differentiation // inferred from electronic annotation /// 0061104 // adrenal chromaffin cell differentiation // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0070849 // response to epidermal growth factor // inferred from electronic annotation /// 0071259 // cellular response to magnetism // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 213769_at AA971768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA971768 /FEA=EST /DB_XREF=gi:3147058 /DB_XREF=est:op86c03.s1 /CLONE=IMAGE:1583716 /UG=Hs.152094 kinase suppressor of ras AA971768 kinase suppressor of ras 1 KSR1 8844 NM_014238 /// XM_006722151 /// XM_006722152 /// XM_006722153 /// XM_006722154 /// XM_006722155 /// XM_006722156 /// XM_006722157 /// XM_006722158 /// XM_006722159 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005078 // MAP-kinase scaffold activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213770_at U43586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U43586.1 /DEF=Human kinase suppressor of ras-1 (KSR1) mRNA, partial cds. /FEA=mRNA /GEN=KSR1 /DB_XREF=gi:1171247 /UG=Hs.152094 kinase suppressor of ras U43586 kinase suppressor of ras 1 KSR1 8844 NM_014238 /// XM_006722151 /// XM_006722152 /// XM_006722153 /// XM_006722154 /// XM_006722155 /// XM_006722156 /// XM_006722157 /// XM_006722158 /// XM_006722159 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005078 // MAP-kinase scaffold activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213771_at AI401612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI401612 /FEA=EST /DB_XREF=gi:4244699 /DB_XREF=est:tf60c01.x1 /CLONE=IMAGE:2103648 /UG=Hs.154680 DKFZP434M154 protein AI401612 interferon regulatory factor 2 binding protein 1 IRF2BP1 26145 NM_015649 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213772_s_at BF196572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196572 /FEA=EST /DB_XREF=gi:11084646 /DB_XREF=est:7m98a04.x1 /CLONE=IMAGE:3563023 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 BF196572 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 213773_x_at AW248552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW248552 /FEA=EST /DB_XREF=gi:6591545 /DB_XREF=est:2820950.3prime /CLONE=IMAGE:2820950 /UG=Hs.295112 KIAA0618 gene product AW248552 NOP2/Sun domain family, member 5 NSUN5 55695 NM_001168347 /// NM_001168348 /// NM_018044 /// NM_148956 /// XM_005277604 /// XR_242255 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213774_s_at AW614578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW614578 /FEA=EST /DB_XREF=gi:7319764 /DB_XREF=est:hh01f08.x1 /CLONE=IMAGE:2953863 /UG=Hs.267819 protein phosphatase 1, regulatory (inhibitor) subunit 2 AW614578 protein phosphatase 1, regulatory (inhibitor) subunit 2 PPP1R2 5504 NM_001291504 /// NM_001291505 /// NM_006241 /// XM_006713682 /// XM_006713683 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213775_x_at AI357871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357871 /FEA=EST /DB_XREF=gi:4109492 /DB_XREF=est:qv13b11.x1 /CLONE=IMAGE:1981437 /UG=Hs.169984 nuclear protein AI357871 zinc finger protein 638 /// ZNF638 intronic transcript 1 (non-protein coding) ZNF638 /// ZNF638-IT1 27332 /// 100507113 NM_001014972 /// NM_001252612 /// NM_001252613 /// NM_014497 /// XM_005264261 /// XM_005264262 /// XM_005264263 /// XM_005264264 /// XM_006711989 /// XM_006711990 /// XR_109944 /// XR_112334 /// XR_171302 /// XR_244928 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213776_at AA583336 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA583336 /FEA=EST /DB_XREF=gi:2367945 /DB_XREF=est:nn45f08.s1 /CLONE=IMAGE:1086855 /UG=Hs.27371 Homo sapiens mRNA; cDNA DKFZp566J123 (from clone DKFZp566J123) AA583336 uncharacterized LOC157562 LOC157562 157562 213777_s_at AI762013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762013 /FEA=EST /DB_XREF=gi:5177680 /DB_XREF=est:wh89e01.x1 /CLONE=IMAGE:2387928 /UG=Hs.29417 HCF-binding transcription factor Zhangfei AI762013 213778_x_at AI983201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983201 /FEA=EST /DB_XREF=gi:5810420 /DB_XREF=est:wz31a05.x1 /CLONE=IMAGE:2559632 /UG=Hs.284153 Fanconi anemia, complementation group A AI983201 zinc finger protein 276 ZNF276 92822 NM_001113525 /// NM_152287 /// NR_110122 /// NR_110126 /// NR_110128 /// NR_110129 /// XM_005256324 /// XM_005256328 /// XM_006721337 /// XR_243507 /// XR_429740 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213779_at AL031186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031186 /DEF=Human DNA sequence from clone CTA-984G1 on chromosome 22q12.1-12.2 Contains the 5 part of the EWSR1 gene for Ewing sarcoma breakpoint region 1 protein, a novel gene and the 3 part of a novel gene with Collagen triple helix repeats. Contains ESTs... /FEA=mRNA_1 /DB_XREF=gi:4581429 /UG=Hs.289106 Human DNA sequence from clone CTA-984G1 on chromosome 22q12.1-12.2 Contains the 5 part of the EWSR1 gene for Ewing sarcoma breakpoint region 1 protein, a novel gene and the 3 part of a novel gene with Collagen triple helix repeats. Contains ESTs, GSSs a AL031186 EMI domain containing 1 EMID1 129080 NM_001267895 /// NM_133455 /// XM_005261328 /// XM_005261329 /// XM_005261330 /// XM_005261333 /// XM_006724132 /// XM_006724133 /// XM_006724134 /// XR_244351 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213780_at N30878 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N30878 /FEA=EST /DB_XREF=gi:1149398 /DB_XREF=est:yw76b05.s1 /CLONE=IMAGE:258129 /UG=Hs.82276 trichohyalin N30878 trichohyalin TCHH 7062 NM_007113 0031424 // keratinization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005509 // calcium ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213781_at AC005757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005757 /DEF=Homo sapiens chromosome 19, cosmid R32611 /FEA=CDS_2 /DB_XREF=gi:3688088 /UG=Hs.31809 hypothetical protein AC005757 protein phosphatase 1, regulatory subunit 37 PPP1R37 284352 NM_019121 /// XM_006723159 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 213782_s_at BF939176 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939176 /FEA=EST /DB_XREF=gi:12356496 /DB_XREF=est:nad84g02.x1 /CLONE=IMAGE:3410474 /UG=Hs.42346 calcineurin-binding protein calsarcin-1 BF939176 myozenin 2 MYOZ2 51778 NM_016599 /// XM_006714234 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // non-traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030346 // protein phosphatase 2B binding // non-traceable author statement /// 0031433 // telethonin binding // inferred from physical interaction 213783_at AI760053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760053 /FEA=EST /DB_XREF=gi:5175720 /DB_XREF=est:wg57f07.x1 /CLONE=IMAGE:2369221 /UG=Hs.31939 manic fringe (Drosophila) homolog AI760053 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase MFNG 4242 NM_001166343 /// NM_002405 /// NR_029413 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213784_at AL037167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037167 /FEA=EST /DB_XREF=gi:5928078 /DB_XREF=est:DKFZp564P1564_s1 /CLONE=DKFZp564P1564 /UG=Hs.50267 putative GTP-binding protein similar to RAYRAB1C AL037167 intraflagellar transport 27 homolog (Chlamydomonas) IFT27 11020 NM_001177701 /// NM_001177702 /// NM_006860 /// NR_033531 /// XM_006724106 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 213785_at AW269792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW269792 /FEA=EST /DB_XREF=gi:6656822 /DB_XREF=est:xv45d03.x1 /CLONE=IMAGE:2816069 /UG=Hs.5010 Homo sapiens clone 24672 mRNA sequence AW269792 importin 9 IPO9 55705 NM_018085 /// XM_006711440 0006606 // protein import into nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0042393 // histone binding // inferred from sequence or structural similarity 213786_at AI935415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935415 /FEA=EST /DB_XREF=gi:5674285 /DB_XREF=est:wo84c03.x1 /CLONE=IMAGE:2462020 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 AI935415 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_001206901 /// NM_001206902 /// NM_006024 /// XM_005249900 0006915 // apoptotic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from sequence or structural similarity 213787_s_at AV702405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702405 /FEA=EST /DB_XREF=gi:10718735 /DB_XREF=est:AV702405 /CLONE=ADBBFA03 /UG=Hs.75105 emopamil-binding protein (sterol isomerase) AV702405 emopamil binding protein (sterol isomerase) EBP 10682 NM_006579 0001501 // skeletal system development // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004769 // steroid delta-isomerase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0015238 // drug transmembrane transporter activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0047750 // cholestenol delta-isomerase activity // inferred from electronic annotation 213788_s_at AI701156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI701156 /FEA=EST /DB_XREF=gi:4989056 /DB_XREF=est:we10f09.x1 /CLONE=IMAGE:2340713 /UG=Hs.6580 Homo sapiens cDNA: FLJ23227 fis, clone CAE00645, highly similar to AF052138 Homo sapiens clone 23718 mRNA sequence AI701156 213789_at N58493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N58493 /FEA=EST /DB_XREF=gi:1202383 /DB_XREF=est:yv72d01.s1 /CLONE=IMAGE:248257 /UG=Hs.75105 emopamil-binding protein (sterol isomerase) N58493 emopamil binding protein (sterol isomerase) EBP 10682 NM_006579 0001501 // skeletal system development // traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004769 // steroid delta-isomerase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0015238 // drug transmembrane transporter activity // traceable author statement /// 0047750 // cholestenol delta-isomerase activity // inferred from electronic annotation 213790_at W46291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W46291 /FEA=EST /DB_XREF=gi:1330989 /DB_XREF=est:zc31b08.s1 /CLONE=IMAGE:323895 /UG=Hs.8850 a disintegrin and metalloproteinase domain 12 (meltrin alpha) W46291 ADAM metallopeptidase domain 12 ADAM12 8038 NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213791_at NM_006211 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006211.1 /DEF=Homo sapiens proenkephalin (PENK), mRNA. /FEA=CDS /GEN=PENK /PROD=proenkephalin /DB_XREF=gi:5453875 /UG=Hs.93557 proenkephalin /FL=gb:NM_006211.1 NM_006211 proenkephalin PENK 5179 NM_001135690 /// NM_006211 0001662 // behavioral fear response // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0002118 // aggressive behavior // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0001515 // opioid peptide activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213792_s_at AA485908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA485908 /FEA=EST /DB_XREF=gi:2216132 /DB_XREF=est:ab38g07.s1 /CLONE=IMAGE:843132 /UG=Hs.89695 insulin receptor AA485908 insulin receptor INSR 3643 NM_000208 /// NM_001079817 /// XM_005259554 /// XM_006722743 /// XM_006722744 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019087 // transformation of host cell by virus // inferred from mutant phenotype /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046326 // positive regulation of glucose import // non-traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048639 // positive regulation of developmental growth // inferred from mutant phenotype /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005899 // insulin receptor complex // inferred from mutant phenotype /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from direct assay /// 0005009 // insulin-activated receptor activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0031995 // insulin-like growth factor II binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction /// 0051425 // PTB domain binding // inferred from physical interaction 213793_s_at BE550452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE550452 /FEA=EST /DB_XREF=gi:9792144 /DB_XREF=est:7a25f02.x1 /CLONE=IMAGE:3219771 /UG=Hs.9192 Homer, neuronal immediate early gene, 1B BE550452 homer homolog 1 (Drosophila) HOMER1 9456 NM_001277077 /// NM_001277078 /// NM_004272 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007206 // phospholipase C-activating G-protein coupled glutamate receptor signaling pathway // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0048875 // chemical homeostasis within a tissue // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0090279 // regulation of calcium ion import // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // traceable author statement /// 2001257 // regulation of cation channel activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0031802 // type 5 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0035256 // G-protein coupled glutamate receptor binding // inferred from electronic annotation /// 0035591 // signaling adaptor activity // inferred by curator /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 213794_s_at AI269117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI269117 /FEA=EST /DB_XREF=gi:3888284 /DB_XREF=est:qj73e04.x1 /CLONE=IMAGE:1865118 /UG=Hs.9043 DKFZP564O092 protein AI269117 neuroguidin, EIF4E binding protein NGDN 25983 NM_001042635 /// NM_015514 0006417 // regulation of translation // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 213795_s_at AL121905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121905 /DEF=Human DNA sequence from clone RP4-534B8 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands. Contains the PTPRA gene for two isoforms of the alpha polypeptide of receptor type protein tyrosine phosphatase, the GNRH2 gene for gonadotropin-re... /FEA=mRNA_3 /DB_XREF=gi:9663349 /UG=Hs.26045 protein tyrosine phosphatase, receptor type, A AL121905 protein tyrosine phosphatase, receptor type, A PTPRA 5786 NM_002836 /// NM_080840 /// NM_080841 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 213796_at AI923984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI923984 /FEA=EST /DB_XREF=gi:5659948 /DB_XREF=est:wn49d12.x1 /CLONE=IMAGE:2448791 /UG=Hs.46320 Small proline-rich protein SPRK human, odontogenic keratocysts, mRNA Partial, 317 nt AI923984 small proline-rich protein 1A SPRR1A 6698 NM_001199828 /// NM_005987 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay 213797_at AI337069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI337069 /FEA=EST /DB_XREF=gi:4073996 /DB_XREF=est:qx82h04.x1 /CLONE=IMAGE:2009047 /UG=Hs.17518 Homo sapiens cig5 mRNA, partial sequence AI337069 radical S-adenosyl methionine domain containing 2 RSAD2 91543 NM_080657 0001503 // ossification // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0034157 // positive regulation of toll-like receptor 7 signaling pathway // inferred from sequence or structural similarity /// 0034165 // positive regulation of toll-like receptor 9 signaling pathway // inferred from sequence or structural similarity /// 0035710 // CD4-positive, alpha-beta T cell activation // inferred from sequence or structural similarity /// 0043367 // CD4-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 213798_s_at AA806142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA806142 /FEA=EST /DB_XREF=gi:2874892 /DB_XREF=est:oe29d06.s1 /CLONE=IMAGE:1409963 /UG=Hs.104125 adenylyl cyclase-associated protein AA806142 CAP, adenylate cyclase-associated protein 1 (yeast) CAP1 10487 NM_001105530 /// NM_006367 /// XM_005270367 /// XM_005270368 /// XM_006710294 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213799_s_at BF740139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF740139 /FEA=EST /DB_XREF=gi:12066815 /DB_XREF=est:7n13d11.x1 /CLONE=IMAGE:3564357 /UG=Hs.26045 protein tyrosine phosphatase, receptor type, A BF740139 protein tyrosine phosphatase, receptor type, A PTPRA 5786 NM_002836 /// NM_080840 /// NM_080841 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 213800_at X04697 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X04697.1 /DEF=Human mRNA for complement factor H 38-kDa N-terminal fragment. /FEA=mRNA /DB_XREF=gi:31991 /UG=Hs.250651 H factor 1 (complement) X04697 complement factor H CFH 3075 NM_000186 /// NM_001014975 /// XM_006711282 /// XM_006711283 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay 213801_x_at AW304232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW304232 /FEA=EST /DB_XREF=gi:6713921 /DB_XREF=est:xv82g01.x1 /CLONE=IMAGE:2825040 /UG=Hs.181357 laminin receptor 1 (67kD, ribosomal protein SA) AW304232 ribosomal protein SA /// ribosomal protein SA pseudogene 19 /// ribosomal protein SA pseudogene 58 /// ribosomal protein SA pseudogene 9 /// small nucleolar RNA, H/ACA box 6 /// small nucleolar RNA, H/ACA box 62 RPSA /// RPSAP19 /// RPSAP58 /// RPSAP9 /// SNORA6 /// SNORA62 3921 /// 6044 /// 388524 /// 574040 /// 653162 /// 730029 NM_001005472 /// NM_001012321 /// NM_002295 /// NR_002324 /// NR_002325 /// NR_003662 /// NR_026890 0000028 // ribosomal small subunit assembly // not recorded /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0000461 // endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006407 // rRNA export from nucleus // not recorded /// 0006412 // translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030686 // 90S preribosome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // not recorded /// 0005055 // laminin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from physical interaction /// 0043236 // laminin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213802_at AI810767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI810767 /FEA=EST /DB_XREF=gi:5397333 /DB_XREF=est:tu04d02.x1 /CLONE=IMAGE:2250051 /UG=Hs.22404 protease, serine, 12 (neurotrypsin, motopsin) AI810767 protease, serine, 12 (neurotrypsin, motopsin) PRSS12 8492 NM_003619 /// XM_005263318 0006508 // proteolysis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0031638 // zymogen activation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043083 // synaptic cleft // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 213803_at BG545463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG545463 /FEA=EST /DB_XREF=gi:13544128 /DB_XREF=est:602572695F1 /CLONE=IMAGE:4701118 /UG=Hs.180446 karyopherin (importin) beta 1 BG545463 karyopherin (importin) beta 1 KPNB1 3837 NM_001276453 /// NM_002265 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006610 // ribosomal protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071782 // endoplasmic reticulum tubular network // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213804_at AI039084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI039084 /FEA=EST /DB_XREF=gi:3278278 /DB_XREF=est:ox26h07.s1 /CLONE=IMAGE:1657501 /UG=Hs.182577 inositol polyphosphate-5-phosphatase, 75kD AI039084 inositol polyphosphate-5-phosphatase, 75kDa INPP5B 3633 NM_001297434 /// NM_005540 /// XM_005270833 /// XM_005270835 /// XM_005270836 /// XM_005270837 /// XM_006710619 /// XM_006710620 /// XM_006710621 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070613 // regulation of protein processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay 213805_at AI692428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI692428 /FEA=EST /DB_XREF=gi:4969768 /DB_XREF=est:wd69c12.x1 /CLONE=IMAGE:2336854 /UG=Hs.184019 Homo sapiens clone 23551 mRNA sequence AI692428 abhydrolase domain containing 5 ABHD5 51099 NM_016006 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006654 // phosphatidic acid biosynthetic process // inferred from direct assay /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from direct assay 213806_at BE222739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222739 /FEA=EST /DB_XREF=gi:8910057 /DB_XREF=est:hu52c11.x1 /CLONE=IMAGE:3173684 /UG=Hs.29117 purine-rich element binding protein A BE222739 purine-rich element binding protein A PURA 5813 NM_005859 0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0032422 // purine-rich negative regulatory element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation 213807_x_at BE870509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE870509 /FEA=EST /DB_XREF=gi:10319285 /DB_XREF=est:601447096F1 /CLONE=IMAGE:3851374 /UG=Hs.285754 met proto-oncogene (hepatocyte growth factor receptor) BE870509 MET proto-oncogene, receptor tyrosine kinase MET 4233 NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 213808_at BE674466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674466 /FEA=EST /DB_XREF=gi:10035007 /DB_XREF=est:7e04e01.x1 /CLONE=IMAGE:3281496 /UG=Hs.12514 Homo sapiens clone 23688 mRNA sequence BE674466 ADAM metallopeptidase domain 23 ADAM23 8745 NM_003812 /// XM_005246932 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 213809_x_at BG393795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG393795 /FEA=EST /DB_XREF=gi:13287243 /DB_XREF=est:602416645F2 /CLONE=IMAGE:4525138 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) BG393795 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 213810_s_at AW007137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007137 /FEA=EST /DB_XREF=gi:5855915 /DB_XREF=est:wt09f08.x1 /CLONE=IMAGE:2506983 /UG=Hs.101514 hypothetical protein FLJ10342 AW007137 213811_x_at AW062341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW062341 /FEA=EST /DB_XREF=gi:6013726 /DB_XREF=est:IL2-CT0031-080899-001-e09 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) AW062341 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 213812_s_at AK024748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024748.1 /DEF=Homo sapiens cDNA: FLJ21095 fis, clone CAS03846. /FEA=mRNA /DB_XREF=gi:10437113 /UG=Hs.108708 calciumcalmodulin-dependent protein kinase kinase 2, beta AK024748 calcium/calmodulin-dependent protein kinase kinase 2, beta CAMKK2 10645 NM_001270485 /// NM_001270486 /// NM_006549 /// NM_153499 /// NM_153500 /// NM_172214 /// NM_172215 /// NM_172216 /// NM_172226 /// XM_005253822 /// XM_005253823 /// XM_005253824 0000165 // MAPK cascade // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0045859 // regulation of protein kinase activity // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213813_x_at AI345238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI345238 /FEA=EST /DB_XREF=gi:4082444 /DB_XREF=est:tb81b07.x1 /CLONE=IMAGE:2060725 /UG=Hs.111334 ferritin, light polypeptide AI345238 213814_s_at AA741303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA741303 /FEA=EST /DB_XREF=gi:2779895 /DB_XREF=est:oc86b03.s1 /CLONE=IMAGE:1356557 /UG=Hs.172278 syntrophin, beta 2 (dystrophin-associated protein A1, 59kD, basic component 2) AA741303 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) SNTB2 6645 NM_006750 /// NM_130845 /// XM_005256120 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213815_x_at AI913329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI913329 /FEA=EST /DB_XREF=gi:5633103 /DB_XREF=est:tz76d03.x1 /CLONE=IMAGE:2294501 /UG=Hs.128425 NY-REN-24 antigen AI913329 cactin, spliceosome C complex subunit CACTIN 58509 NM_001080543 /// NM_021231 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213816_s_at AA005141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA005141 /FEA=EST /DB_XREF=gi:1448644 /DB_XREF=est:zh95e08.s1 /CLONE=IMAGE:429062 /UG=Hs.285754 met proto-oncogene (hepatocyte growth factor receptor) AA005141 MET proto-oncogene, receptor tyrosine kinase MET 4233 NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 213817_at AL049435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049435.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B0220 (from clone DKFZp586B0220). /FEA=mRNA /DB_XREF=gi:4500218 /UG=Hs.170056 Homo sapiens mRNA; cDNA DKFZp586B0220 (from clone DKFZp586B0220) AL049435 interleukin-1 receptor-associated kinase 3 IRAK3 11213 NM_001142523 /// NM_007199 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred by curator /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0009615 // response to virus // inferred by curator /// 0010933 // positive regulation of macrophage tolerance induction // inferred from sequence or structural similarity /// 0010936 // negative regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032494 // response to peptidoglycan // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from mutant phenotype /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0043244 // regulation of protein complex disassembly // inferred from sequence or structural similarity /// 0043330 // response to exogenous dsRNA // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 213818_x_at AI862325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI862325 /FEA=EST /DB_XREF=gi:5526432 /DB_XREF=est:tw71h04.x1 /CLONE=IMAGE:2265175 /UG=Hs.146428 collagen, type V, alpha 1 AI862325 transmembrane protein 223 TMEM223 79064 NM_001080501 0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005588 // collagen type V trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 213819_s_at H45696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H45696 /FEA=EST /DB_XREF=gi:921748 /DB_XREF=est:yp23f04.s1 /CLONE=IMAGE:188287 /UG=Hs.179986 flotillin 1 H45696 flotillin 1 FLOT1 10211 NM_005803 /// XM_005248780 /// XM_005248781 /// XM_005272759 /// XM_005272760 /// XM_005274909 /// XM_005274910 /// XM_005275335 /// XM_005275336 /// XM_005275502 /// XM_005275503 /// XM_006714947 /// XM_006725465 /// XM_006725672 /// XM_006725971 /// XM_006726072 0007409 // axonogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005901 // caveola // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0016600 // flotillin complex // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 213820_s_at T54159 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T54159 /FEA=EST /DB_XREF=gi:656020 /DB_XREF=est:ya90f07.s2 /CLONE=IMAGE:68965 /UG=Hs.172803 hypothetical protein MGC10327 T54159 StAR-related lipid transfer (START) domain containing 5 STARD5 80765 NM_030574 /// NM_181900 /// XM_006720702 /// XM_006720703 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 213821_s_at AI819115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI819115 /FEA=EST /DB_XREF=gi:5438118 /DB_XREF=est:wj79c02.x1 /CLONE=IMAGE:2409026 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) AI819115 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0043202 // lysosomal lumen // traceable author statement 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213822_s_at BE856776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856776 /FEA=EST /DB_XREF=gi:10370143 /DB_XREF=est:7f68f09.x1 /CLONE=IMAGE:3299849 /UG=Hs.17639 Homo sapiens ubiquitin protein ligase (UBE3B) mRNA, partial cds BE856776 ubiquitin protein ligase E3B UBE3B 89910 NM_001270449 /// NM_001270450 /// NM_001270451 /// NM_130466 /// NM_183414 /// NM_183415 /// XM_005253987 /// XM_006719681 /// XM_006719682 /// XR_429118 /// XR_429119 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 213823_at H94842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H94842 /FEA=EST /DB_XREF=gi:1102475 /DB_XREF=est:yu57a03.s1 /CLONE=IMAGE:230188 /UG=Hs.17882 ESTs H94842 homeobox A11 HOXA11 3207 NM_005523 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001759 // organ induction // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0007501 // mesodermal cell fate specification // inferred from sequence or structural similarity /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010720 // positive regulation of cell development // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from sequence or structural similarity /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213824_at AI870776 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI870776 /FEA=EST /DB_XREF=gi:5544744 /DB_XREF=est:wl76g04.x1 /CLONE=IMAGE:2430870 /UG=Hs.176977 protein kinase C binding protein 2 AI870776 oligodendrocyte lineage transcription factor 2 OLIG2 10215 NM_005806 /// XM_005260908 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 213825_at AA757419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA757419 /FEA=EST /DB_XREF=gi:2805282 /DB_XREF=est:zg36b11.s1 /CLONE=IMAGE:395421 /UG=Hs.176977 protein kinase C binding protein 2 AA757419 oligodendrocyte lineage transcription factor 2 OLIG2 10215 NM_005806 /// XM_005260908 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021529 // spinal cord oligodendrocyte cell differentiation // inferred from electronic annotation /// 0021530 // spinal cord oligodendrocyte cell fate specification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 213826_s_at AA292281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA292281 /FEA=EST /DB_XREF=gi:1940261 /DB_XREF=est:zt51b03.s1 /CLONE=IMAGE:725837 /UG=Hs.181307 H3 histone, family 3A AA292281 H3 histone, family 3A H3F3A 3020 NM_002107 213827_at AL137579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137579.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A1010 (from clone DKFZp434A1010); partial cds. /FEA=mRNA /GEN=DKFZp434A1010 /PROD=hypothetical protein /DB_XREF=gi:6808292 /UG=Hs.21036 Homo sapiens mRNA; cDNA DKFZp434A1010 (from clone DKFZp434A1010); partial cds AL137579 Rho GTPase activating protein 33 ARHGAP33 115703 NM_001172630 /// NM_052948 /// XM_005258487 /// XM_005258488 /// XM_005258489 /// XM_006722999 /// XM_006723000 /// XM_006723001 /// XM_006723002 /// XM_006723003 /// XR_430187 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 213828_x_at AA477655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA477655 /FEA=EST /DB_XREF=gi:2206289 /DB_XREF=est:zu37h09.s1 /CLONE=IMAGE:740225 /UG=Hs.181307 H3 histone, family 3A AA477655 H3 histone, family 3A /// H3 histone, family 3A, pseudogene 4 /// H3 histone, family 3B (H3.3B) H3F3A /// H3F3AP4 /// H3F3B 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213829_x_at AK000485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000485.1 /DEF=Homo sapiens cDNA FLJ20478 fis, clone KAT07359. /FEA=mRNA /DB_XREF=gi:7020605 /UG=Hs.194676 DKFZP434C013 protein AK000485 regulator of telomere elongation helicase 1 RTEL1 51750 NM_001283009 /// NM_001283010 /// NM_016434 /// NM_032957 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from sequence or structural similarity /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 213830_at AW007751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007751 /FEA=EST /DB_XREF=gi:5856529 /DB_XREF=est:wt68f10.x1 /CLONE=IMAGE:2512651 /UG=Hs.2014 T cell receptor delta locus AW007751 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213831_at X00452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X00452.1 /DEF=Human mRNA for DC classII histocompatibility antigen alpha-chain. /FEA=mRNA /PROD=DC classII histocompatibility antigenalpha-chain /DB_XREF=gi:32265 /UG=Hs.198253 major histocompatibility complex, class II, DQ alpha 1 X00452 major histocompatibility complex, class II, DQ alpha 1 /// HLA class II histocompatibility antigen, DQ alpha 1 chain-like HLA-DQA1 /// LOC100509457 3117 /// 100509457 NM_002122 /// XM_003120269 /// XM_003846468 /// XM_005274953 /// XM_005275108 /// XM_005275333 /// XM_005275542 /// XM_005275544 /// XM_005276080 /// XM_006715079 /// XM_006725484 /// XM_006725999 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 213832_at AA530995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA530995 /FEA=EST /DB_XREF=gi:2273701 /DB_XREF=est:nj07a02.s1 /CLONE=IMAGE:985610 /UG=Hs.23729 Homo sapiens clone 24405 mRNA sequence AA530995 potassium voltage-gated channel, Shal-related subfamily, member 3 KCND3 3752 NM_004980 /// NM_172198 /// XM_005270851 /// XM_006710629 /// XM_006710630 /// XM_006710631 /// XM_006710632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0086009 // membrane repolarization // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005250 // A-type (transient outward) potassium channel activity // not recorded /// 0005250 // A-type (transient outward) potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213833_x_at AA931929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA931929 /FEA=EST /DB_XREF=gi:3086315 /DB_XREF=est:oo62c05.s1 /CLONE=IMAGE:1570760 /UG=Hs.227152 mannan-binding lectin serine protease 1 (C4C2 activating component of Ra-reactive factor) AA931929 NOP16 nucleolar protein NOP16 51491 NM_001256539 /// NM_001256540 /// NM_001291305 /// NM_001291306 /// NM_001291307 /// NM_001291308 /// NM_016391 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 213834_at AB029033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029033.1 /DEF=Homo sapiens mRNA for KIAA1110 protein, partial cds. /FEA=mRNA /GEN=KIAA1110 /PROD=KIAA1110 protein /DB_XREF=gi:5689556 /UG=Hs.22479 KIAA1110 protein AB029033 IQ motif and Sec7 domain 3 IQSEC3 440073 NM_001170738 /// NM_015232 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0030054 // cell junction // not recorded /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060077 // inhibitory synapse // inferred from electronic annotation 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 213835_x_at AL524262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL524262 /FEA=EST /DB_XREF=gi:12787755 /DB_XREF=est:AL524262 /CLONE=CS0DC002YD01 (3 prime) /UG=Hs.246112 KIAA0788 protein AL524262 GTP binding protein 3 (mitochondrial) GTPBP3 84705 NM_001128855 /// NM_001195422 /// NM_032620 /// NM_133644 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006400 // tRNA modification // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 213836_s_at AW052084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW052084 /FEA=EST /DB_XREF=gi:5914443 /DB_XREF=est:wy86f07.x1 /CLONE=IMAGE:2555461 /UG=Hs.279937 KIAA1001 protein AW052084 WD repeat domain, phosphoinositide interacting 1 WIPI1 55062 NM_017983 /// XM_005257497 0000045 // autophagic vacuole assembly // not recorded /// 0006914 // autophagy // inferred from expression pattern /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048203 // vesicle targeting, trans-Golgi to endosome // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0000407 // pre-autophagosomal structure // inferred from direct assay /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 213837_at Z98752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98752 /DEF=Human DNA sequence from clone RP1-138B7 on chromosome 20q13.12. Contains the 3 end of the gene for a Drosophila lethal (3) malignant brain tumor (l(3)mbt) protein homolog and KIAA0681 and DFKZp586P1522, the SGK2 gene for serumglucocorticoid regu... /FEA=mRNA_4 /DB_XREF=gi:9408718 /UG=Hs.278516 DKFZP586P1522 protein Z98752 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213838_at AA191426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA191426 /FEA=EST /DB_XREF=gi:1780105 /DB_XREF=est:zp83g09.s1 /CLONE=IMAGE:626848 /UG=Hs.279886 RAN binding protein 9 AA191426 nucleolar protein 7, 27kDa NOL7 51406 NM_016167 /// XM_005249173 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 213839_at AW028110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW028110 /FEA=EST /DB_XREF=gi:5886866 /DB_XREF=est:wv26a10.x1 /CLONE=IMAGE:2530650 /UG=Hs.301478 KIAA0500 protein AW028110 calmin (calponin-like, transmembrane) CLMN 79789 NM_024734 /// XM_006720256 /// XR_245721 /// XR_245722 /// XR_429330 /// XR_429331 /// XR_429332 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213840_s_at R68573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R68573 /FEA=EST /DB_XREF=gi:842090 /DB_XREF=est:yh99d05.s1 /CLONE=IMAGE:137865 /UG=Hs.9964 mitochondrial ribosomal protein S12 R68573 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005761 // mitochondrial ribosome // traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213841_at BE223030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE223030 /FEA=EST /DB_XREF=gi:8910348 /DB_XREF=est:hu46c02.x1 /CLONE=IMAGE:3173090 /UG=Hs.301281 Homo sapiens mRNA, chromosome 1 specific transcript KIAA0510 BE223030 tenascin R TNR 7143 NM_003285 0007155 // cell adhesion // non-traceable author statement /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0008306 // associative learning // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0048692 // negative regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0072534 // perineuronal net // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 213842_x_at AK021688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021688.1 /DEF=Homo sapiens cDNA FLJ11626 fis, clone HEMBA1004203, weakly similar to NUCLEOLAR PROTEIN NOP2. /FEA=mRNA /DB_XREF=gi:10432923 /UG=Hs.295112 KIAA0618 gene product AK021688 NOP2/Sun domain family, member 5 pseudogene 1 /// NOP2/Sun domain family, member 5 pseudogene 2 NSUN5P1 /// NSUN5P2 155400 /// 260294 NM_001039487 /// NM_001039575 /// NM_001039576 /// NM_148936 /// NM_148980 /// NR_033322 /// NR_033323 /// NR_104013 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213843_x_at AW276522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW276522 /FEA=EST /DB_XREF=gi:6663552 /DB_XREF=est:xr15a02.x1 /CLONE=IMAGE:2760170 /UG=Hs.291904 accessory proteins BAP31BAP29 AW276522 solute carrier family 6 (neurotransmitter transporter), member 8 SLC6A8 6535 NM_001142805 /// NM_001142806 /// NM_005629 0006600 // creatine metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0015871 // choline transport // inferred from electronic annotation /// 0015881 // creatine transport // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // non-traceable author statement /// 1902598 // creatine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005308 // creatine transmembrane transporter activity // non-traceable author statement /// 0005309 // creatine:sodium symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 213844_at NM_019102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_019102.1 /DEF=Homo sapiens homeo box A5 (HOXA5), mRNA. /FEA=CDS /GEN=HOXA5 /PROD=homeobox protein (HOX-1.3) /DB_XREF=gi:9506790 /UG=Hs.37034 homeo box A5 /FL=gb:NM_019102.1 NM_019102 homeobox A5 HOXA5 3202 NM_019102 0001501 // skeletal system development // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010870 // positive regulation of receptor biosynthetic process // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0030324 // lung development // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045639 // positive regulation of myeloid cell differentiation // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060435 // bronchiole development // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060481 // lobar bronchus epithelium development // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060535 // trachea cartilage morphogenesis // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060764 // cell-cell signaling involved in mammary gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 213845_at AL355532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL355532 /DEF=Human DNA sequence from clone RP11-487F5 on chromosome 6 Contains the 3 part of the GRIK2 (glutamate receptor, ionotropic, kainate 2) gene, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:10045412 /UG=Hs.301676 glutamate receptor, ionotropic, kainate 2 /FL=gb:NM_021956.1 gb:U16126.1 AL355532 glutamate receptor, ionotropic, kainate 2 GRIK2 2898 NM_001166247 /// NM_021956 /// NM_175768 /// XM_005266945 /// XM_005266946 /// XM_006715465 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from mutant phenotype /// 0050804 // regulation of synaptic transmission // inferred from direct assay /// 0050806 // positive regulation of synaptic transmission // inferred from mutant phenotype /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay 213846_at AA382702 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA382702 /FEA=EST /DB_XREF=gi:2035020 /DB_XREF=est:EST95939 /UG=Hs.3462 cytochrome c oxidase subunit VIIc AA382702 cytochrome c oxidase subunit VIIc COX7C 1350 NM_001867 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 213847_at NM_006262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006262.1 /DEF=Homo sapiens peripherin (PRPH), mRNA. /FEA=CDS /GEN=PRPH /PROD=peripherin /DB_XREF=gi:5453985 /UG=Hs.37044 peripherin /FL=gb:NM_006262.1 NM_006262 peripherin PRPH 5630 NM_006262 /// XM_005269025 /// XM_006719503 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation 0005882 // intermediate filament // traceable author statement /// 0005883 // neurofilament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044299 // C-fiber // inferred from electronic annotation /// 0045098 // type III intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213848_at AI655015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655015 /FEA=EST /DB_XREF=gi:4738994 /DB_XREF=est:wb66a10.x1 /CLONE=IMAGE:2310618 /UG=Hs.3843 Homo sapiens mRNA; cDNA DKFZp586F2224 (from clone DKFZp586F2224) AI655015 dual specificity phosphatase 7 DUSP7 1849 NM_001947 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay 213849_s_at AA974416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA974416 /FEA=EST /DB_XREF=gi:3149596 /DB_XREF=est:oq26b05.s1 /CLONE=IMAGE:1587441 /UG=Hs.7688 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform AA974416 protein phosphatase 2, regulatory subunit B, beta PPP2R2B 5521 NM_001271899 /// NM_001271900 /// NM_001271948 /// NM_181674 /// NM_181675 /// NM_181676 /// NM_181677 /// NM_181678 /// NR_073526 /// NR_073527 0000266 // mitochondrial fission // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 213850_s_at AI984932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984932 /FEA=EST /DB_XREF=gi:5812209 /DB_XREF=est:wr86e12.x1 /CLONE=IMAGE:2494606 /UG=Hs.51957 splicing factor, arginineserine-rich 2, interacting protein AI984932 SR-related CTD-associated factor 11 SCAF11 9169 NM_004719 /// XM_005269230 /// XM_006719692 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213851_at BG031677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG031677 /FEA=EST /DB_XREF=gi:12422203 /DB_XREF=est:602300830F1 /CLONE=IMAGE:4402326 /UG=Hs.58210 ESTs BG031677 transmembrane protein 110 TMEM110 375346 NM_198563 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213852_at BG289199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289199 /FEA=EST /DB_XREF=gi:13044802 /DB_XREF=est:602387595F1 /CLONE=IMAGE:4516438 /UG=Hs.65648 RNA binding motif protein 8A BG289199 RNA binding motif protein 8A RBM8A 9939 NM_005105 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213853_at AL050199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050199.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D0923 (from clone DKFZp586D0923). /FEA=mRNA /DB_XREF=gi:4884438 /UG=Hs.62669 Homo sapiens mRNA; cDNA DKFZp586D0923 (from clone DKFZp586D0923) AL050199 DnaJ (Hsp40) homolog, subfamily C, member 24 DNAJC24 120526 NM_181706 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from direct assay /// 0008198 // ferrous iron binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213854_at BF511590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511590 /FEA=EST /DB_XREF=gi:11594888 /DB_XREF=est:UI-H-BI4-aol-b-08-0-UI.s1 /CLONE=IMAGE:3085023 /UG=Hs.6139 synaptogyrin 1 BF511590 synaptogyrin 1 SYNGR1 9145 NM_004711 /// NM_145731 /// NM_145738 0006605 // protein targeting // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 213855_s_at AI500366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI500366 /FEA=EST /DB_XREF=gi:4392348 /DB_XREF=est:tm95g11.x1 /CLONE=IMAGE:2165924 /UG=Hs.95351 lipase, hormone-sensitive AI500366 lipase, hormone-sensitive LIPE 3991 NM_005357 /// XM_005258937 /// XM_005258938 /// XM_005258939 /// XM_005258940 /// XM_005258941 /// XM_006723218 0006468 // protein phosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from sequence or structural similarity /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0042758 // long-chain fatty acid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046340 // diacylglycerol catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016298 // lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033878 // hormone-sensitive lipase activity // inferred from electronic annotation 213856_at BG230614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230614 /FEA=EST /DB_XREF=gi:12725656 /DB_XREF=est:naf41b12.x1 /CLONE=IMAGE:4143335 /UG=Hs.82685 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) BG230614 CD47 molecule CD47 961 NM_001025079 /// NM_001025080 /// NM_001777 /// NM_198793 /// XM_005247908 /// XM_005247909 /// XR_241521 /// XR_241522 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008228 // opsonization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009617 // response to bacterium // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0070053 // thrombospondin receptor activity // inferred from physical interaction 213857_s_at BG230614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG230614 /FEA=EST /DB_XREF=gi:12725656 /DB_XREF=est:naf41b12.x1 /CLONE=IMAGE:4143335 /UG=Hs.82685 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) BG230614 CD47 molecule CD47 961 NM_001025079 /// NM_001025080 /// NM_001777 /// NM_198793 /// XM_005247908 /// XM_005247909 /// XR_241521 /// XR_241522 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008228 // opsonization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009617 // response to bacterium // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0070053 // thrombospondin receptor activity // inferred from physical interaction 213858_at BE350026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE350026 /FEA=EST /DB_XREF=gi:9261879 /DB_XREF=est:ht08a08.x1 /CLONE=IMAGE:3146102 /UG=Hs.78547 zinc finger protein (clone 647) BE350026 zinc finger protein 250 ZNF250 58500 NM_001109689 /// NM_021061 /// XM_005272327 /// XM_005272328 /// XM_005272330 /// XM_005272331 /// XM_006716612 /// XM_006716613 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 213859_x_at AI652586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652586 /FEA=EST /DB_XREF=gi:4736565 /DB_XREF=est:wb61h07.x1 /CLONE=IMAGE:2310205 /UG=Hs.9456 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 AI652586 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 SMARCA5 8467 NM_003601 0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005677 // chromatin silencing complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0031010 // ISWI-type complex // inferred from electronic annotation /// 0031213 // RSF complex // inferred from physical interaction /// 0043596 // nuclear replication fork // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay 213860_x_at AW268585 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW268585 /FEA=EST /DB_XREF=gi:6655615 /DB_XREF=est:xv34g06.x1 /CLONE=IMAGE:2815066 /UG=Hs.84264 acidic protein rich in leucines AW268585 casein kinase 1, alpha 1 CSNK1A1 1452 NM_001025105 /// NM_001271741 /// NM_001271742 /// NM_001892 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213861_s_at N67741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N67741 /FEA=EST /DB_XREF=gi:1219866 /DB_XREF=est:za01g09.s1 /CLONE=IMAGE:291328 /UG=Hs.49378 DKFZP586D0919 protein N67741 methyltransferase like 21B METTL21B 25895 NM_015433 /// NM_206914 0032259 // methylation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213862_at AI979087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI979087 /FEA=EST /DB_XREF=gi:5804117 /DB_XREF=est:wr70c11.x1 /CLONE=IMAGE:2493044 /UG=Hs.118463 transport-secretion protein 2.2, AI979087 213863_s_at AW611641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW611641 /FEA=EST /DB_XREF=gi:7316827 /DB_XREF=est:hg91g11.x1 /CLONE=IMAGE:2953028 /UG=Hs.288936 Homo sapiens, Similar to RIKEN cDNA C330013D18 gene, clone MGC:11226, mRNA, complete cds AW611641 ornithine decarboxylase antizyme 3 OAZ3 51686 NM_001134939 /// NM_016178 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0015847 // putrescine transport // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity /// 1902268 // negative regulation of polyamine transmembrane transport // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation /// 0015489 // putrescine transmembrane transporter activity // inferred from sequence or structural similarity /// 0071532 // ankyrin repeat binding // inferred from electronic annotation 213864_s_at AI985751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI985751 /FEA=EST /DB_XREF=gi:5813028 /DB_XREF=est:wr76h07.x1 /CLONE=IMAGE:2493661 /UG=Hs.179662 nucleosome assembly protein 1-like 1 AI985751 nucleosome assembly protein 1-like 1 NAP1L1 4673 NM_004537 /// NM_139207 /// XM_005268895 /// XM_005268896 /// XM_006719422 /// XM_006719423 /// XM_006719424 /// XM_006719425 /// XR_245930 /// XR_245931 /// XR_245932 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213865_at AI378788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI378788 /FEA=EST /DB_XREF=gi:4188641 /DB_XREF=est:tc67b04.x1 /CLONE=IMAGE:2069647 /UG=Hs.153445 Human mRNA for unknown product, partial cds AI378788 discoidin, CUB and LCCL domain containing 2 DCBLD2 131566 NM_080927 0007155 // cell adhesion // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // non-traceable author statement /// 0042060 // wound healing // inferred from direct assay 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213866_at AL134453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134453 /FEA=EST /DB_XREF=gi:6602640 /DB_XREF=est:DKFZp547J135_s1 /CLONE=DKFZp547J135 /UG=Hs.106890 Homo sapiens clone 23771 mRNA sequence AL134453 sterile alpha motif domain containing 14 SAMD14 201191 NM_001257359 /// NM_174920 /// XM_005257132 /// XM_006721752 /// XM_006721753 0005515 // protein binding // inferred from electronic annotation 213867_x_at AA809056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA809056 /FEA=EST /DB_XREF=gi:2878462 /DB_XREF=est:nw17a02.s1 /CLONE=IMAGE:1240682 /UG=Hs.288061 actin, beta AA809056 actin, beta ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 213868_s_at AW243128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW243128 /FEA=EST /DB_XREF=gi:6576929 /DB_XREF=est:xm92h02.x1 /CLONE=IMAGE:2691699 /UG=Hs.109201 CGI-86 protein AW243128 dehydrogenase/reductase (SDR family) member 7 DHRS7 51635 NM_016029 /// XM_005267757 0055114 // oxidation-reduction process // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 213869_x_at AA218868 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA218868 /FEA=EST /DB_XREF=gi:1833030 /DB_XREF=est:zr01g01.s1 /CLONE=IMAGE:650256 /UG=Hs.125359 Thy-1 cell surface antigen AA218868 Thy-1 cell surface antigen THY1 7070 NM_006288 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // non-traceable author statement /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034235 // GPI anchor binding // inferred from sequence or structural similarity 213870_at AL031228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031228 /DEF=Human DNA sequence from clone 1033B10 on chromosome 6p21.2-21.31. Contains the BING5 gene, exons 11 to 15 of the BING4 gene, the gene for GalT3 (beta3-Galactosyltransferase), the RPS18 (40S ribosomal protein S18) gene, the SACM2L (suppressor of ac... /FEA=mRNA_7 /DB_XREF=gi:3646023 /UG=Hs.121509 collagen, type XI, alpha 2 AL031228 collagen, type XI, alpha 2 COL11A2 1302 NM_001163771 /// NM_080679 /// NM_080680 /// NM_080681 0001501 // skeletal system development // inferred from mutant phenotype /// 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030020 // extracellular matrix structural constituent conferring tensile strength // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213871_s_at AA523444 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA523444 /FEA=EST /DB_XREF=gi:2264156 /DB_XREF=est:ng30d12.s1 /CLONE=IMAGE:936311 /UG=Hs.109752 putative c-Myc-responsive AA523444 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 DNPH1 10591 NM_006443 /// NM_199184 0008283 // cell proliferation // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009159 // deoxyribonucleoside monophosphate catabolic process // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050144 // nucleoside deoxyribosyltransferase activity // inferred from electronic annotation /// 0070694 // deoxyribonucleoside 5'-monophosphate N-glycosidase activity // inferred from sequence or structural similarity 213872_at BE465032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE465032 /FEA=EST /DB_XREF=gi:9510807 /DB_XREF=est:hv76g09.x1 /CLONE=IMAGE:3179392 /UG=Hs.173685 hypothetical protein FLJ12619 BE465032 213873_at D29810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D29810.1 /DEF=Human mRNA for unknown product, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:704440 /UG=Hs.153445 Human mRNA for unknown product, partial cds D29810 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 ST3GAL6 10402 NM_001271142 /// NM_001271145 /// NM_001271146 /// NM_001271147 /// NM_001271148 /// NM_006100 /// XM_005247067 /// XM_005247068 /// XM_005247069 /// XM_005247070 /// XM_005247071 /// XM_005247072 /// XM_006713474 /// XM_006713475 /// XM_006713476 /// XR_427357 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // inferred from direct assay /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071354 // cellular response to interleukin-6 // inferred from expression pattern /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052798 // beta-galactoside alpha-2,3-sialyltransferase activity // inferred from direct assay 213874_at NM_006215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006215.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4), mRNA. /FEA=CDS /GEN=SERPINA4 /PROD=serine (or cysteine) proteinase inhibitor, cladeA (alpha-1 antiproteinase, antitrypsin), member 4 /DB_XREF=gi:5453887 /UG=Hs.159628 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 /FL=gb:L19684.1 gb:NM_006215.1 NM_006215 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 SERPINA4 5267 NM_001289032 /// NM_001289033 /// NM_006215 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 213875_x_at BG252842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG252842 /FEA=EST /DB_XREF=gi:12762658 /DB_XREF=est:602365421F1 /CLONE=IMAGE:4473701 /UG=Hs.173685 hypothetical protein FLJ12619 BG252842 chromosome 6 open reading frame 62 C6orf62 81688 NM_030939 /// XM_005249433 0005622 // intracellular // inferred from direct assay 213876_x_at AW089584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW089584 /FEA=EST /DB_XREF=gi:6046928 /DB_XREF=est:xd20f04.x1 /CLONE=IMAGE:2594335 /UG=Hs.171909 U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2 AW089584 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 ZRSR2 8233 NM_005089 /// XM_005274597 /// XM_006724519 /// XM_006724520 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030628 // pre-mRNA 3'-splice site binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 213877_x_at AI568533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI568533 /FEA=EST /DB_XREF=gi:4531907 /DB_XREF=est:tn40e01.x1 /CLONE=IMAGE:2170104 /UG=Hs.172772 transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) AI568533 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) TCEB2 6923 NM_007108 /// NM_207013 /// XM_006720937 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070449 // elongin complex // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 213878_at AI685944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI685944 /FEA=EST /DB_XREF=gi:4897238 /DB_XREF=est:tu38g02.x1 /CLONE=IMAGE:2253362 /UG=Hs.235069 RecQ protein-like (DNA helicase Q1-like) AI685944 pyridine nucleotide-disulphide oxidoreductase domain 1 PYROXD1 79912 NM_024854 /// XM_006719153 /// XR_242902 0055114 // oxidation-reduction process // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 213879_at AV726646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV726646 /FEA=EST /DB_XREF=gi:10836067 /DB_XREF=est:AV726646 /CLONE=HTCAPG08 /UG=Hs.180139 SMT3 (suppressor of mif two 3, yeast) homolog 2 AV726646 213880_at AL524520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL524520 /FEA=EST /DB_XREF=gi:12788013 /DB_XREF=est:AL524520 /CLONE=CS0DC007YG21 (3 prime) /UG=Hs.285529 G protein-coupled receptor 49 AL524520 leucine-rich repeat containing G protein-coupled receptor 5 LGR5 8549 NM_001277226 /// NM_001277227 /// NM_003667 /// NR_110596 /// XM_005269204 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 213881_x_at AI971724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI971724 /FEA=EST /DB_XREF=gi:5768550 /DB_XREF=est:wr07a04.x1 /CLONE=IMAGE:2480814 /UG=Hs.180139 SMT3 (suppressor of mif two 3, yeast) homolog 2 AI971724 small ubiquitin-related modifier 2-like /// small ubiquitin-like modifier 2 /// small ubiquitin-like modifier 3 LOC101929087 /// SUMO2 /// SUMO3 6612 /// 6613 /// 101929087 NM_001005849 /// NM_001286416 /// NM_006936 /// NM_006937 /// XM_005250081 /// XM_005276013 /// XM_005276311 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213882_at AA012917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA012917 /FEA=EST /DB_XREF=gi:1473944 /DB_XREF=est:ze27c03.s1 /CLONE=IMAGE:360196 /UG=Hs.180532 glucose phosphate isomerase AA012917 TM2 domain containing 1 TM2D1 83941 NM_032027 /// XM_005271250 /// XR_246299 0006915 // apoptotic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 213883_s_at AA012917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA012917 /FEA=EST /DB_XREF=gi:1473944 /DB_XREF=est:ze27c03.s1 /CLONE=IMAGE:360196 /UG=Hs.180532 glucose phosphate isomerase AA012917 TM2 domain containing 1 TM2D1 83941 NM_032027 /// XM_005271250 /// XR_246299 0006915 // apoptotic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 213884_s_at AA114843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA114843 /FEA=EST /DB_XREF=gi:1669911 /DB_XREF=est:zl02f12.s1 /CLONE=IMAGE:491183 /UG=Hs.183454 Homo sapiens mRNA; cDNA DKFZp434N1221 (from clone DKFZp434N1221) AA114843 tripartite motif containing 3 TRIM3 10612 NM_001248006 /// NM_001248007 /// NM_006458 /// NM_033278 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213885_at AA114843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA114843 /FEA=EST /DB_XREF=gi:1669911 /DB_XREF=est:zl02f12.s1 /CLONE=IMAGE:491183 /UG=Hs.183454 Homo sapiens mRNA; cDNA DKFZp434N1221 (from clone DKFZp434N1221) AA114843 tripartite motif containing 3 TRIM3 10612 NM_001248006 /// NM_001248007 /// NM_006458 /// NM_033278 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213887_s_at AI554759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI554759 /FEA=EST /DB_XREF=gi:4487122 /DB_XREF=est:tn30e02.x1 /CLONE=IMAGE:2169146 /UG=Hs.24301 polymerase (RNA) II (DNA directed) polypeptide E (25kD) AI554759 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa POLR2E 5434 NM_002695 /// XM_005259579 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213888_s_at AL022398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022398 /DEF=Homo sapiens DNA sequence from PAC 434O14 on chromosome 1q32.3.-41. Contains the HSD11B1 gene for Hydroxysteroid (11-beta) Dehydrogenase 1, the ADORA2BP adenosine A2b receptor LIKE pseudogene, the IRF6 gene for Interferon Regulatory Factor 6 and t... /FEA=mRNA_3 /DB_XREF=gi:3355547 /UG=Hs.261373 hypothetical protein dJ434O14.3 AL022398 TRAF3 interacting protein 3 TRAF3IP3 80342 NM_001287754 /// NM_025228 /// NR_109871 /// XM_005273279 /// XM_005273280 /// XR_247044 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213889_at AI742901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742901 /FEA=EST /DB_XREF=gi:5111189 /DB_XREF=est:wg47f06.x1 /CLONE=IMAGE:2368259 /UG=Hs.27008 phosphatidylinositol glycan, class L AI742901 phosphatidylinositol glycan anchor biosynthesis, class L PIGL 9487 NM_004278 /// XM_006721596 /// XR_243571 /// XR_429826 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // non-traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000225 // N-acetylglucosaminylphosphatidylinositol deacetylase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 213890_x_at AI200589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI200589 /FEA=EST /DB_XREF=gi:3753195 /DB_XREF=est:qf99c03.x1 /CLONE=IMAGE:1758148 /UG=Hs.80617 ribosomal protein S16 AI200589 ribosomal protein S16 RPS16 6217 NM_001020 /// XM_005259137 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213891_s_at AI927067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927067 /FEA=EST /DB_XREF=gi:5663031 /DB_XREF=est:wo87f01.x1 /CLONE=IMAGE:2462329 /UG=Hs.289068 Homo sapiens cDNA FLJ11918 fis, clone HEMBB1000272 AI927067 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 213892_s_at AA927724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA927724 /FEA=EST /DB_XREF=gi:3076544 /DB_XREF=est:om72g04.s1 /CLONE=IMAGE:1552758 /UG=Hs.28914 adenine phosphoribosyltransferase AA927724 adenine phosphoribosyltransferase APRT 353 NM_000485 /// NM_001030018 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006168 // adenine salvage // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002055 // adenine binding // inferred from electronic annotation /// 0003999 // adenine phosphoribosyltransferase activity // traceable author statement /// 0016208 // AMP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 213893_x_at AA161026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA161026 /FEA=EST /DB_XREF=gi:1735280 /DB_XREF=est:zo62a12.s1 /CLONE=IMAGE:591454 /UG=Hs.292996 postmeiotic segregation increased 2-like 2 AA161026 postmeiotic segregation increased 2 pseudogene 5 /// postmeiotic segregation increased 2 pseudogene 9 PMS2P5 /// PMS2P9 5383 /// 100132832 NM_001129851 /// NM_174930 /// NR_027775 /// NR_027776 /// NR_027777 /// NR_028058 0006298 // mismatch repair // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 213894_at BF447246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF447246 /FEA=EST /DB_XREF=gi:11512384 /DB_XREF=est:7p46g06.x1 /CLONE=IMAGE:3648970 /UG=Hs.29900 KIAA0960 protein BF447246 thrombospondin, type I, domain containing 7A THSD7A 221981 NM_015204 /// XM_006715659 /// XM_006715660 /// XM_006715661 /// XM_006715662 0001525 // angiogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 213895_at BF445047 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF445047 /FEA=EST /DB_XREF=gi:11510185 /DB_XREF=est:nad20g10.x1 /CLONE=IMAGE:3366330 /UG=Hs.79368 epithelial membrane protein 1 BF445047 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 213896_x_at BE856549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE856549 /FEA=EST /DB_XREF=gi:10369681 /DB_XREF=est:7f64b02.x1 /CLONE=IMAGE:3299403 /UG=Hs.44131 KIAA0974 protein BE856549 family with sequence similarity 149, member B1 FAM149B1 317662 NM_173348 /// XM_005269744 /// XM_005269745 /// XM_005269746 /// XM_005269747 /// XM_006717815 213897_s_at AI832239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI832239 /FEA=EST /DB_XREF=gi:5452910 /DB_XREF=est:td14f05.x1 /CLONE=IMAGE:2075649 /UG=Hs.3254 mitochondrial ribosomal protein L23 AI832239 mitochondrial ribosomal protein L23 MRPL23 6150 NM_021134 /// XM_006718271 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 213898_at AW149379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149379 /FEA=EST /DB_XREF=gi:6197275 /DB_XREF=est:xf36d11.x1 /CLONE=IMAGE:2620149 /UG=Hs.5011 RNA binding motif protein 9 AW149379 RNA binding protein, fox-1 homolog (C. elegans) 2 RBFOX2 23543 NM_001031695 /// NM_001082576 /// NM_001082577 /// NM_001082578 /// NM_001082579 /// NM_014309 /// XM_005261428 /// XM_005261429 /// XM_005261430 /// XM_005261431 /// XM_005261432 /// XM_005261433 /// XM_005261435 /// XM_005261437 /// XM_006724185 /// XM_006724186 /// XM_006724187 /// XM_006724188 /// XM_006724189 /// XM_006724190 /// XM_006724191 /// XM_006724192 /// XM_006724193 /// XM_006724194 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010724 // regulation of definitive erythrocyte differentiation // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0021942 // radial glia guided migration of Purkinje cell // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213899_at AI743685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743685 /FEA=EST /DB_XREF=gi:5111973 /DB_XREF=est:wg41f10.x1 /CLONE=IMAGE:2367691 /UG=Hs.78935 methionine aminopeptidase; eIF-2-associated p67 AI743685 methionyl aminopeptidase 2 METAP2 10988 NM_006838 /// XM_005268583 0006508 // proteolysis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031365 // N-terminal protein amino acid modification // inferred from direct assay /// 0070084 // protein initiator methionine removal // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from electronic annotation 213900_at AA524029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524029 /FEA=EST /DB_XREF=gi:2264957 /DB_XREF=est:ng32f02.s1 /CLONE=IMAGE:936507 /UG=Hs.77889 Friedreich ataxia region gene X123 AA524029 family with sequence similarity 189, member A2 FAM189A2 9413 NM_001127608 /// NM_004816 /// XM_005252307 /// XM_005252308 /// XM_005252309 /// XM_005252310 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213901_x_at AW149379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149379 /FEA=EST /DB_XREF=gi:6197275 /DB_XREF=est:xf36d11.x1 /CLONE=IMAGE:2620149 /UG=Hs.5011 RNA binding motif protein 9 AW149379 RNA binding protein, fox-1 homolog (C. elegans) 2 RBFOX2 23543 NM_001031695 /// NM_001082576 /// NM_001082577 /// NM_001082578 /// NM_001082579 /// NM_014309 /// XM_005261428 /// XM_005261429 /// XM_005261430 /// XM_005261431 /// XM_005261432 /// XM_005261433 /// XM_005261435 /// XM_005261437 /// XM_006724185 /// XM_006724186 /// XM_006724187 /// XM_006724188 /// XM_006724189 /// XM_006724190 /// XM_006724191 /// XM_006724192 /// XM_006724193 /// XM_006724194 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010724 // regulation of definitive erythrocyte differentiation // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0021942 // radial glia guided migration of Purkinje cell // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213902_at AI379338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI379338 /FEA=EST /DB_XREF=gi:4189191 /DB_XREF=est:tc73g05.x1 /CLONE=IMAGE:2070296 /UG=Hs.75811 N-acylsphingosine amidohydrolase (acid ceramidase) AI379338 N-acylsphingosine amidohydrolase (acid ceramidase) 1 ASAH1 427 NM_001127505 /// NM_004315 /// NM_177924 /// XM_005273504 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017040 // ceramidase activity // traceable author statement 213903_s_at AI380850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI380850 /FEA=EST /DB_XREF=gi:4190703 /DB_XREF=est:tg17a02.x1 /CLONE=IMAGE:2109002 /UG=Hs.94211 rcd1 (required for cell differentiation, S.pombe) homolog 1 AI380850 RCD1 required for cell differentiation1 homolog (S. pombe) RQCD1 9125 NM_001271634 /// NM_001271635 /// NM_005444 /// NR_073390 /// XM_005246942 /// XM_005246943 /// XM_006712832 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 2000327 // positive regulation of ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213904_at AL390170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390170.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547E184 (from clone DKFZp547E184). /FEA=mRNA /DB_XREF=gi:9368866 /UG=Hs.8077 Homo sapiens mRNA; cDNA DKFZp547E184 (from clone DKFZp547E184) AL390170 ferric-chelate reductase 1-like FRRS1L 23732 NM_014334 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 213905_x_at AA845258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA845258 /FEA=EST /DB_XREF=gi:2931709 /DB_XREF=est:ak84a11.s1 /CLONE=IMAGE:1414556 /UG=Hs.821 biglycan AA845258 biglycan BGN 633 NM_001711 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 213906_at AW592266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW592266 /FEA=EST /DB_XREF=gi:7279443 /DB_XREF=est:hf48e04.x1 /CLONE=IMAGE:2935134 /UG=Hs.300592 v-myb avian myeloblastosis viral oncogene homolog-like 1 AW592266 v-myb avian myeloblastosis viral oncogene homolog-like 1 MYBL1 4603 NM_001080416 /// NM_001144755 /// NM_001294282 /// XM_005251251 /// XM_006716450 /// XM_006716451 /// XM_006716452 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // non-traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 213907_at N32257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32257 /FEA=EST /DB_XREF=gi:1152656 /DB_XREF=est:yy28d09.s1 /CLONE=IMAGE:272561 /UG=Hs.298581 eukaryotic translation elongation factor 1 epsilon 1 N32257 eukaryotic translation elongation factor 1 epsilon 1 EEF1E1 9521 NM_001135650 /// NM_004280 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 213908_at AI824078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI824078 /FEA=EST /DB_XREF=gi:5444749 /DB_XREF=est:wj35h06.x1 /CLONE=IMAGE:2404859 /UG=Hs.295446 ESTs, Moderately similar to 810024C cytochrome oxidase I H.sapiens AI824078 WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2 /// WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3 WHAMMP2 /// WHAMMP3 339005 /// 440253 NR_003521 /// NR_026589 213909_at AU147799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147799 /FEA=EST /DB_XREF=gi:11009320 /DB_XREF=est:AU147799 /CLONE=MAMMA1001744 /UG=Hs.288467 Homo sapiens cDNA FLJ12280 fis, clone MAMMA1001744 AU147799 leucine rich repeat containing 15 LRRC15 131578 NM_001135057 /// NM_130830 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0046813 // receptor-mediated virion attachment to host cell // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay 213910_at AW770896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW770896 /FEA=EST /DB_XREF=gi:7702945 /DB_XREF=est:hn54g08.x1 /CLONE=IMAGE:3027518 /UG=Hs.119206 insulin-like growth factor binding protein 7 AW770896 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001253835 /// NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051414 // response to cortisol // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 213911_s_at BF718636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF718636 /FEA=EST /DB_XREF=gi:12019549 /DB_XREF=est:KEST107 /CLONE=S90891.NIH-8-R /UG=Hs.119192 H2A histone family, member Z BF718636 H2A histone family, member Z H2AFZ 3015 NM_002106 /// XM_005262971 0006334 // nucleosome assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213912_at AW134976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134976 /FEA=EST /DB_XREF=gi:6138522 /DB_XREF=est:UI-H-BI1-abt-a-05-0-UI.s1 /CLONE=IMAGE:2712849 /UG=Hs.11912 KIAA0984 protein AW134976 TBC1 domain family, member 30 TBC1D30 23329 NM_015279 /// XM_006719300 /// XM_006719301 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 213913_s_at AW134976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134976 /FEA=EST /DB_XREF=gi:6138522 /DB_XREF=est:UI-H-BI1-abt-a-05-0-UI.s1 /CLONE=IMAGE:2712849 /UG=Hs.11912 KIAA0984 protein AW134976 TBC1 domain family, member 30 TBC1D30 23329 NM_015279 /// XM_006719300 /// XM_006719301 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 213914_s_at R85779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R85779 /FEA=EST /DB_XREF=gi:944185 /DB_XREF=est:yq23f07.s1 /CLONE=IMAGE:274693 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 R85779 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213915_at NM_005601 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005601.1 /DEF=Homo sapiens natural killer cell group 7 sequence (NKG7), mRNA. /FEA=CDS /GEN=NKG7 /PROD=natural killer cell group 7 sequence /DB_XREF=gi:5031948 /UG=Hs.10306 natural killer cell group 7 sequence /FL=gb:NM_005601.1 NM_005601 natural killer cell granule protein 7 NKG7 4818 NM_005601 /// XM_005258955 /// XM_006723228 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213916_at AU154474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154474 /FEA=EST /DB_XREF=gi:11015995 /DB_XREF=est:AU154474 /CLONE=NT2RP4001197 /UG=Hs.110956 zinc finger protein 20 (KOX 13) AU154474 zinc finger protein 20 /// ZNF625-ZNF20 readthrough (NMD candidate) ZNF20 /// ZNF625-ZNF20 7568 /// 100529855 NM_001203250 /// NM_021143 /// NR_037802 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213917_at BE465829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE465829 /FEA=EST /DB_XREF=gi:9511604 /DB_XREF=est:hx80h09.x1 /CLONE=IMAGE:3194177 /UG=Hs.150539 Homo sapiens cDNA FLJ13793 fis, clone THYRO1000085, highly similar to PAIRED BOX PROTEIN PAX-8, ISOFORMS 8A8B BE465829 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 213918_s_at BF221673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF221673 /FEA=EST /DB_XREF=gi:11128850 /DB_XREF=est:7o60b03.x1 /CLONE=IMAGE:3578429 /UG=Hs.287586 Homo sapiens cDNA FLJ13648 fis, clone PLACE1011340, weakly similar to Homo sapiens IDN3-B mRNA BF221673 Nipped-B homolog (Drosophila) NIPBL 25836 NM_015384 /// NM_133433 /// XM_005248280 /// XM_005248282 /// XM_005248283 /// XM_006714467 /// XM_006714468 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001656 // metanephros development // non-traceable author statement /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from direct assay /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from mutant phenotype /// 0035261 // external genitalia morphogenesis // inferred from mutant phenotype /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from mutant phenotype /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045995 // regulation of embryonic development // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0048638 // regulation of developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0061010 // gall bladder development // inferred from mutant phenotype /// 0061038 // uterus morphogenesis // inferred from mutant phenotype /// 0071481 // cellular response to X-ray // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070087 // chromo shadow domain binding // inferred from physical interaction 213919_at AW024467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024467 /FEA=EST /DB_XREF=gi:5877997 /DB_XREF=est:wu76g06.x1 /CLONE=IMAGE:2526010 /UG=Hs.172847 DnaJ (Hsp40) homolog, subfamily C, member 4 AW024467 DnaJ (Hsp40) homolog, subfamily C, member 4 DNAJC4 3338 NM_005528 /// XM_006718529 /// XM_006718530 0006457 // protein folding // non-traceable author statement /// 0006986 // response to unfolded protein // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 213920_at AB006631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB006631.1 /DEF=Homo sapiens mRNA for KIAA0293 gene, partial cds. /FEA=mRNA /GEN=KIAA0293 /DB_XREF=gi:2564333 /UG=Hs.12784 KIAA0293 protein AB006631 cut-like homeobox 2 CUX2 23316 NM_015267 /// XM_006719299 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007614 // short-term memory // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 213921_at NM_001048 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001048.1 /DEF=Homo sapiens somatostatin (SST), mRNA. /FEA=CDS /GEN=SST /PROD=somatostatin /DB_XREF=gi:4507242 /UG=Hs.12409 somatostatin /FL=gb:NM_001048.1 NM_001048 somatostatin SST 6750 NM_001048 0001101 // response to acid // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008628 // hormone-mediated apoptotic signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005179 // hormone activity // traceable author statement 213922_at AW294686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW294686 /FEA=EST /DB_XREF=gi:6701322 /DB_XREF=est:UI-H-BW0-ail-h-04-0-UI.s1 /CLONE=IMAGE:2729719 /UG=Hs.125836 KIAA0847 protein AW294686 tau tubulin kinase 2 TTBK2 146057 NM_173500 /// XM_005254171 /// XM_005254173 /// XM_006720402 /// XM_006720403 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213923_at AW005535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW005535 /FEA=EST /DB_XREF=gi:5854313 /DB_XREF=est:wz87d04.x1 /CLONE=IMAGE:2565799 /UG=Hs.155218 E1B-55kDa-associated protein 5 AW005535 RAP2B, member of RAS oncogene family RAP2B 5912 NM_002886 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0061097 // regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 213924_at BF476502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF476502 /FEA=EST /DB_XREF=gi:11547329 /DB_XREF=est:naa27a03.x1 /CLONE=IMAGE:3255844 /UG=Hs.154145 hypothetical protein FLJ11585 BF476502 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type GNAL 2774 NM_001142339 /// NM_001261443 /// NM_001261444 /// NM_002071 /// NM_182978 /// XM_006722323 /// XM_006722324 /// XR_243798 0001975 // response to amphetamine // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // not recorded /// 0031000 // response to caffeine // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 213925_at AL134612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134612 /FEA=EST /DB_XREF=gi:6602799 /DB_XREF=est:DKFZp547E086_s1 /CLONE=DKFZp547E086 /UG=Hs.167036 Homo sapiens clone 23798 and 23825 mRNA sequence AL134612 chromosome 1 open reading frame 95 C1orf95 375057 NM_001003665 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213926_s_at AI742626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742626 /FEA=EST /DB_XREF=gi:5110914 /DB_XREF=est:wg44c03.x1 /CLONE=IMAGE:2367940 /UG=Hs.171545 HIV-1 Rev binding protein AI742626 ArfGAP with FG repeats 1 AGFG1 3267 NM_001135187 /// NM_001135188 /// NM_001135189 /// NM_004504 /// XM_005246516 /// XM_006712478 /// XM_006712479 /// XM_006712480 /// XM_006712481 0001675 // acrosome assembly // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213927_at AV753204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV753204 /FEA=EST /DB_XREF=gi:10911052 /DB_XREF=est:AV753204 /CLONE=NPDBDB08 /UG=Hs.170267 ESTs AV753204 mitogen-activated protein kinase kinase kinase 9 MAP3K9 4293 NM_001284230 /// NM_001284231 /// NM_001284232 /// NM_033141 /// XM_005267683 /// XM_006720149 /// XM_006720150 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007256 // activation of JNKK activity // inferred from sequence or structural similarity /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004706 // JUN kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004708 // MAP kinase kinase activity // non-traceable author statement /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 213928_s_at AI742626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742626 /FEA=EST /DB_XREF=gi:5110914 /DB_XREF=est:wg44c03.x1 /CLONE=IMAGE:2367940 /UG=Hs.171545 HIV-1 Rev binding protein AI742626 ArfGAP with FG repeats 1 AGFG1 3267 NM_001135187 /// NM_001135188 /// NM_001135189 /// NM_004504 /// XM_005246516 /// XM_006712478 /// XM_006712479 /// XM_006712480 /// XM_006712481 0006406 // mRNA export from nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005643 // nuclear pore // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 213929_at AL050204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050204.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1223 (from clone DKFZp586F1223). /FEA=mRNA /DB_XREF=gi:4884443 /UG=Hs.28540 Homo sapiens mRNA; cDNA DKFZp586F1223 (from clone DKFZp586F1223) AL050204 exophilin 5 EXPH5 23086 NM_001144763 /// NM_001144765 /// NM_015065 /// XM_005271461 /// XM_005271462 /// XM_005271463 0003334 // keratinocyte development // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction 213930_at N51708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N51708 /FEA=EST /DB_XREF=gi:1192874 /DB_XREF=est:yy72e03.s1 /CLONE=IMAGE:279100 /UG=Hs.182723 Homo sapiens mRNA from chromosome 5q21-22, clone:843Ex N51708 autophagy related 12 ATG12 9140 NM_001277783 /// NM_004707 /// NR_033362 /// NR_033363 /// NR_073603 /// NR_073604 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // /// 0002376 // immune system process // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0044804 // nucleophagy // /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // 213931_at AI819238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI819238 /FEA=EST /DB_XREF=gi:5438328 /DB_XREF=est:wj42g05.x1 /CLONE=IMAGE:2405528 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein AI819238 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /// inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) ID2 /// ID2B 3398 /// 84099 NM_001039082 /// NM_002166 /// NR_026582 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred by curator /// 0090398 // cellular senescence // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 213932_x_at AI923492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI923492 /FEA=EST /DB_XREF=gi:5659456 /DB_XREF=est:wn86a02.x1 /CLONE=IMAGE:2452682 /UG=Hs.181244 major histocompatibility complex, class I, A AI923492 major histocompatibility complex, class I, A HLA-A 3105 NM_001242758 /// NM_002116 /// XM_005275331 /// XM_006725750 /// XM_006725751 /// XM_006725857 /// XM_006725858 /// XM_006725859 /// XM_006725946 /// XM_006726046 /// XM_006726047 /// XM_006726135 /// XM_006726136 /// XM_006726137 /// XR_430999 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2000568 // positive regulation of memory T cell activation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005797 // Golgi medial cisterna // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // inferred from direct assay /// 0030881 // beta-2-microglobulin binding // inferred from sequence or structural similarity /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0042608 // T cell receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046977 // TAP binding // inferred from direct assay 213933_at AW242315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW242315 /FEA=EST /DB_XREF=gi:6576069 /DB_XREF=est:xm96d12.x1 /CLONE=IMAGE:2692055 /UG=Hs.27860 Homo sapiens mRNA; cDNA DKFZp586M0723 (from clone DKFZp586M0723) AW242315 prostaglandin E receptor 3 (subtype EP3) PTGER3 5733 NM_000957 /// NM_001126044 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 /// NR_028292 /// NR_028293 /// NR_028294 0001660 // fever generation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // non-traceable author statement 213934_s_at AL567808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567808 /FEA=EST /DB_XREF=gi:12921536 /DB_XREF=est:AL567808 /CLONE=CS0DF033YC17 (3 prime) /UG=Hs.22182 zinc finger protein 23 (KOX 16) AL567808 zinc finger protein 23 ZNF23 7571 NM_145911 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 213935_at AF007132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007132.1 /DEF=Homo sapiens clone 23551 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852606 /UG=Hs.184019 Homo sapiens clone 23551 mRNA sequence AF007132 abhydrolase domain containing 5 ABHD5 51099 NM_016006 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006654 // phosphatidic acid biosynthetic process // inferred from direct assay /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from direct assay 213936_x_at AW276646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW276646 /FEA=EST /DB_XREF=gi:6663676 /DB_XREF=est:xr17f12.x1 /CLONE=IMAGE:2760431 /UG=Hs.264330 N-acylsphingosine amidohydrolase (acid ceramidase)-like AW276646 surfactant protein B SFTPB 6439 NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation 213937_s_at AV723177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV723177 /FEA=EST /DB_XREF=gi:10826357 /DB_XREF=est:AV723177 /CLONE=HTBBUC07 /UG=Hs.23170 homolog of yeast SPB1 AV723177 FtsJ RNA methyltransferase homolog 1 (E. coli) FTSJ1 24140 NM_001282157 /// NM_012280 /// NM_177439 /// XM_005272595 /// XR_246715 /// XR_246716 /// XR_430505 0001510 // RNA methylation // inferred from electronic annotation /// 0002128 // tRNA nucleoside ribose methylation // inferred from electronic annotation /// 0002181 // cytoplasmic translation // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008175 // tRNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213938_at Z38645 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z38645 /FEA=EST /DB_XREF=gi:561037 /DB_XREF=est:HSC0JE042 /CLONE=c-0je04 /UG=Hs.7006 KIAA0378 protein Z38645 ELKS/RAB6-interacting/CAST family member 2 ERC2 26059 NM_015576 /// XM_005265036 /// XM_006713101 /// XR_245112 /// XR_245113 /// XR_245114 /// XR_245115 /// XR_245116 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213939_s_at AI871641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871641 /FEA=EST /DB_XREF=gi:5545690 /DB_XREF=est:we28f04.x1 /CLONE=IMAGE:2342431 /UG=Hs.306623 Homo sapiens cDNA FLJ12012 fis, clone HEMBB1001668 AI871641 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 213940_s_at AU145053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145053 /FEA=EST /DB_XREF=gi:11006574 /DB_XREF=est:AU145053 /CLONE=HEMBA1003755 /UG=Hs.301763 KIAA0554 protein AU145053 formin binding protein 1 FNBP1 23048 NM_015033 /// XM_005251815 /// XM_005251816 /// XM_005251817 /// XM_005251818 /// XM_005251819 /// XM_005251820 /// XM_005251821 /// XM_005251822 /// XM_005251823 /// XM_005251824 /// XM_005251825 /// XM_005251826 /// XM_005251827 /// XM_005251828 /// XM_005251829 /// XM_005251830 /// XM_005251831 /// XM_005251832 /// XM_005251833 /// XM_005251834 /// XM_006717016 /// XM_006717017 0006412 // translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 213941_x_at AI970731 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI970731 /FEA=EST /DB_XREF=gi:5767485 /DB_XREF=est:wr14b05.x1 /CLONE=IMAGE:2481489 /UG=Hs.301547 ribosomal protein S7 AI970731 ribosomal protein S7 RPS7 6201 NM_001011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030686 // 90S preribosome // not recorded /// 0032040 // small-subunit processome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213942_at AL134303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134303 /FEA=EST /DB_XREF=gi:6602490 /DB_XREF=est:DKFZp547K034_r1 /CLONE=DKFZp547K034 /UG=Hs.56186 EGF-like-domain, multiple 3 AL134303 multiple EGF-like-domains 6 MEGF6 1953 NM_001409 /// XM_006710406 /// XM_006710407 /// XM_006710408 /// XM_006710409 /// XM_006710410 /// XR_426590 /// XR_426591 /// XR_426592 /// XR_426593 0005576 // extracellular region // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213943_at X99268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X99268.1 /DEF=H.sapiens mRNA for B-HLH DNA binding protein. /FEA=mRNA /GEN=H-twist /PROD=B-HLH DNA binding protein /DB_XREF=gi:1495422 /UG=Hs.66744 twist (Drosophila) homolog (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) /FL=gb:NM_000474.1 X99268 twist family bHLH transcription factor 1 TWIST1 7291 NM_000474 /// XM_006715769 /// XR_428085 /// XR_428086 /// XR_428087 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001503 // ossification // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003180 // aortic valve morphogenesis // inferred from mutant phenotype /// 0003183 // mitral valve morphogenesis // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from electronic annotation /// 0003253 // cardiac neural crest cell migration involved in outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from mutant phenotype /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0033128 // negative regulation of histone phosphorylation // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035137 // hindlimb morphogenesis // inferred from electronic annotation /// 0035359 // negative regulation of peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0044092 // negative regulation of molecular function // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // non-traceable author statement /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // traceable author statement /// 0060900 // embryonic camera-type eye formation // inferred from mutant phenotype /// 0061029 // eyelid development in camera-type eye // inferred from mutant phenotype /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0071639 // positive regulation of monocyte chemotactic protein-1 production // inferred from mutant phenotype /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2000147 // positive regulation of cell motility // non-traceable author statement /// 2000276 // negative regulation of oxidative phosphorylation uncoupler activity // inferred from electronic annotation /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from mutant phenotype /// 2000773 // negative regulation of cellular senescence // inferred from mutant phenotype /// 2000778 // positive regulation of interleukin-6 secretion // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype /// 2000793 // cell proliferation involved in heart valve development // inferred from mutant phenotype /// 2000802 // positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 213944_x_at BG236220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG236220 /FEA=EST /DB_XREF=gi:12750151 /DB_XREF=est:naf25h11.x1 /CLONE=IMAGE:4142085 /UG=Hs.323067 Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194) BG236220 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 213945_s_at AA909765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA909765 /FEA=EST /DB_XREF=gi:3050564 /DB_XREF=est:ok88d11.s1 /CLONE=IMAGE:1521045 /UG=Hs.56966 KIAA0906 protein AA909765 nucleoporin 210kDa NUP210 23225 NM_024923 /// XM_005264994 /// XR_245105 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0046983 // protein dimerization activity // inferred from electronic annotation 213946_s_at AI633851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633851 /FEA=EST /DB_XREF=gi:4685181 /DB_XREF=est:tt04c06.x1 /CLONE=IMAGE:2239786 /UG=Hs.6654 KIAA0657 protein AI633851 obscurin-like 1 OBSL1 23363 NM_001173408 /// NM_001173431 /// NM_015311 /// XM_005246421 /// XM_005246423 /// XM_005246424 /// XM_005246425 /// XM_005246427 /// XM_006712386 /// XM_006712387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0050775 // positive regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0014704 // intercalated disc // traceable author statement /// 0030018 // Z disc // traceable author statement /// 0031430 // M band // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // traceable author statement /// 1990393 // 3M complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation 213947_s_at AI867102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI867102 /FEA=EST /DB_XREF=gi:5540136 /DB_XREF=est:wd99b10.x1 /CLONE=IMAGE:2339707 /UG=Hs.56966 KIAA0906 protein AI867102 nucleoporin 210kDa NUP210 23225 NM_024923 /// XM_005264994 /// XR_245105 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 213948_x_at AI564838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI564838 /FEA=EST /DB_XREF=gi:4523295 /DB_XREF=est:tn37h02.x1 /CLONE=IMAGE:2169843 /UG=Hs.6164 hypothetical protein FLJ10698 AI564838 cell adhesion molecule 3 CADM3 57863 NM_001127173 /// NM_021189 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 213949_s_at AI370867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI370867 /FEA=EST /DB_XREF=gi:4149620 /DB_XREF=est:ta63h11.x1 /CLONE=IMAGE:2048805 /UG=Hs.91103 Homo sapiens, Similar to CG2245 gene product, clone MGC:4293, mRNA, complete cds AI370867 deoxyhypusine hydroxylase/monooxygenase DOHH 83475 NM_001145165 /// NM_031304 0008612 // peptidyl-lysine modification to peptidyl-hypusine // inferred from mutant phenotype /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019135 // deoxyhypusine monooxygenase activity // inferred from mutant phenotype /// 0019135 // deoxyhypusine monooxygenase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213950_s_at BE670265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE670265 /FEA=EST /DB_XREF=gi:10030806 /DB_XREF=est:7e32d08.x1 /CLONE=IMAGE:3284175 /UG=Hs.75206 protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) BE670265 protein phosphatase 3, catalytic subunit, gamma isozyme PPP3CC 5533 NM_001243974 /// NM_001243975 /// NM_005605 /// XM_005273564 /// XR_428312 0006915 // apoptotic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213951_s_at BE964655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964655 /FEA=EST /DB_XREF=gi:11768198 /DB_XREF=est:601658585R1 /CLONE=IMAGE:3885812 /UG=Hs.78185 MAX-like bHLHZIP protein BE964655 PSMC3 interacting protein PSMC3IP 29893 NM_001256014 /// NM_001256015 /// NM_001256016 /// NM_013290 /// NM_016556 /// NR_045669 /// NR_045670 /// NR_045671 0006310 // DNA recombination // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype 213952_s_at AI372974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI372974 /FEA=EST /DB_XREF=gi:4152840 /DB_XREF=est:qz17f12.x1 /CLONE=IMAGE:2021807 /UG=Hs.89499 arachidonate 5-lipoxygenase AI372974 arachidonate 5-lipoxygenase ALOX5 240 NM_000698 /// NM_001256153 /// NM_001256154 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0004051 // arachidonate 5-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 213953_at AI732381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732381 /FEA=EST /DB_XREF=gi:5053494 /DB_XREF=est:ng30h05.x5 /CLONE=IMAGE:936345 /UG=Hs.84905 cytokeratin 20 AI732381 keratin 20 KRT20 54474 NM_019010 /// XM_005257464 /// XM_005277792 0006915 // apoptotic process // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from mutant phenotype /// 0050708 // regulation of protein secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 213954_at AB020695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020695.1 /DEF=Homo sapiens mRNA for KIAA0888 protein, partial cds. /FEA=mRNA /GEN=KIAA0888 /PROD=KIAA0888 protein /DB_XREF=gi:4240264 /UG=Hs.91662 KIAA0888 protein AB020695 family with sequence similarity 169, member A FAM169A 26049 NM_015566 /// NR_046462 /// XM_005248479 /// XM_005248480 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 213955_at BE673151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE673151 /FEA=EST /DB_XREF=gi:10033692 /DB_XREF=est:7d30a11.x1 /CLONE=IMAGE:3248732 /UG=Hs.91626 Homo sapiens clone B18 unknown mRNA BE673151 myozenin 3 MYOZ3 91977 NM_001122853 /// NM_133371 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 213956_at AW299294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299294 /FEA=EST /DB_XREF=gi:6708971 /DB_XREF=est:xs38h10.x1 /CLONE=IMAGE:2771971 /UG=Hs.92200 KIAA0480 gene product AW299294 centrosomal protein 350kDa CEP350 9857 NM_014810 /// XM_005245638 /// XM_006711666 /// XM_006711667 /// XM_006711668 /// XM_006711669 /// XM_006711670 /// XM_006711671 0034453 // microtubule anchoring // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 213957_s_at AA635523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA635523 /FEA=EST /DB_XREF=gi:2559365 /DB_XREF=est:nr36c06.s1 /CLONE=IMAGE:1170058 /UG=Hs.92200 KIAA0480 gene product AA635523 centrosomal protein 350kDa CEP350 9857 NM_014810 /// XM_005245638 /// XM_006711666 /// XM_006711667 /// XM_006711668 /// XM_006711669 /// XM_006711670 /// XM_006711671 0034453 // microtubule anchoring // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 213958_at AW134823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134823 /FEA=EST /DB_XREF=gi:6138369 /DB_XREF=est:UI-H-BI1-abs-c-11-0-UI.s1 /CLONE=IMAGE:2712956 /UG=Hs.81226 CD6 antigen AW134823 CD6 molecule CD6 923 NM_001254750 /// NM_001254751 /// NM_006725 /// NR_045638 /// XM_006718738 /// XM_006718739 /// XM_006718740 /// XM_006718741 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 213959_s_at BF515597 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF515597 /FEA=EST /DB_XREF=gi:11600776 /DB_XREF=est:UI-H-BW1-anq-g-11-0-UI.s1 /CLONE=IMAGE:3083325 /UG=Hs.12328 KIAA1005 protein BF515597 RPGRIP1-like RPGRIP1L 23322 NM_001127897 /// NM_015272 /// XM_005255867 /// XM_005255868 /// XM_005255869 /// XM_005255870 /// XM_005255871 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0021532 // neural tube patterning // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043584 // nose development // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0060039 // pericardium development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0005930 // axoneme // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031870 // thromboxane A2 receptor binding // inferred from physical interaction 213960_at T87225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T87225 /FEA=EST /DB_XREF=gi:715577 /DB_XREF=est:yc81f06.s1 /CLONE=IMAGE:22392 /UG=Hs.13223 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 51358 T87225 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 213961_s_at AI077556 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI077556 /FEA=EST /DB_XREF=gi:3411964 /DB_XREF=est:oz33f08.x1 /CLONE=IMAGE:1677159 /UG=Hs.131846 PCAF associated factor 65 alpha AI077556 213962_s_at AI924382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924382 /FEA=EST /DB_XREF=gi:5660346 /DB_XREF=est:wn60d01.x1 /CLONE=IMAGE:2449825 /UG=Hs.100729 KIAA0692 protein AI924382 ankyrin repeat and LEM domain containing 2 ANKLE2 23141 NM_015114 /// XM_005266159 /// XM_005266160 /// XM_005266161 /// XM_006719735 0000278 // mitotic cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007084 // mitotic nuclear envelope reassembly // inferred from mutant phenotype /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 213963_s_at AW589975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW589975 /FEA=EST /DB_XREF=gi:7277100 /DB_XREF=est:hg28b08.x1 /CLONE=IMAGE:2946903 /UG=Hs.20985 sin3-associated polypeptide, 30kD AW589975 Sin3A-associated protein, 30kDa SAP30 8819 NM_003864 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 213964_x_at AI307586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI307586 /FEA=EST /DB_XREF=gi:4002311 /DB_XREF=est:tb35h12.x1 /CLONE=IMAGE:2056391 /UG=Hs.133130 Homo sapiens mRNA; cDNA DKFZp566H0124 (from clone DKFZp566H0124) AI307586 RPARP antisense RNA 1 RPARP-AS1 100505761 NR_038937 /// NR_038938 213965_s_at AL035406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035406 /DEF=Human DNA sequence from clone RP1-233K16 on chromosome 1p36.21-36.33 Contains the gene KIAA0444, a putative chromodomain helicase DNA binding protein 3 (CHD3), the gene for potassium channel beta 2 subunit (KCNK2), two CpG island, ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:8977826 /UG=Hs.158291 KIAA0444 protein AL035406 chromodomain helicase DNA binding protein 5 CHD5 26038 NM_015557 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from sequence or structural similarity /// 0043967 // histone H4 acetylation // inferred from sequence or structural similarity /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from mutant phenotype /// 0098532 // histone H3-K27 trimethylation // inferred from mutant phenotype /// 1901798 // positive regulation of signal transduction by p53 class mediator // inferred from sequence or structural similarity 0000792 // heterochromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061628 // H3K27me3 modified histone binding // inferred from direct assay 213966_at N25429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25429 /FEA=EST /DB_XREF=gi:1139870 /DB_XREF=est:yx76b02.s1 /CLONE=IMAGE:267627 /UG=Hs.32317 high-mobility group 20B N25429 high mobility group 20B HMG20B 10362 NM_006339 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033234 // negative regulation of protein sumoylation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 213967_at AI634532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI634532 /FEA=EST /DB_XREF=gi:4685862 /DB_XREF=est:tx52e09.x1 /CLONE=IMAGE:2273224 /UG=Hs.13423 Homo sapiens clone 24468 mRNA sequence AI634532 RALY RNA binding protein-like RALYL 138046 NM_001100391 /// NM_001100392 /// NM_001100393 /// NM_001287243 /// NM_001287244 /// NM_173848 /// XM_005251169 /// XM_006716421 /// XM_006716422 /// XM_006716423 /// XM_006716424 /// XM_006716425 /// XM_006716426 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213968_at AA748177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA748177 /FEA=EST /DB_XREF=gi:2788135 /DB_XREF=est:nx98e03.s1 /CLONE=IMAGE:1270300 /UG=Hs.20709 tetraspan 5 AA748177 213969_x_at BF683426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF683426 /FEA=EST /DB_XREF=gi:11968834 /DB_XREF=est:602139603F1 /CLONE=IMAGE:4300777 /UG=Hs.183698 ribosomal protein L29 BF683426 ribosomal protein L29 RPL29 6159 NM_000992 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 213970_at AA744682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA744682 /FEA=EST /DB_XREF=gi:2783446 /DB_XREF=est:ny26b06.s1 /CLONE=IMAGE:1272851 /UG=Hs.184075 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA744682 RAB, member of RAS oncogene family-like 3 RABL3 285282 NM_173825 /// XM_006713595 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 213971_s_at AI924660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924660 /FEA=EST /DB_XREF=gi:5660624 /DB_XREF=est:wn74a05.x1 /CLONE=IMAGE:2451536 /UG=Hs.197803 KIAA0160 protein AI924660 SUZ12 polycomb repressive complex 2 subunit /// suppressor of zeste 12 homolog pseudogene 1 SUZ12 /// SUZ12P1 23512 /// 440423 NM_015355 /// NR_024187 /// XM_005257954 /// XM_006721794 /// XR_243773 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from mutant phenotype 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from mutant phenotype 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213972_at AI080288 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI080288 /FEA=EST /DB_XREF=gi:3416539 /DB_XREF=est:oz51f04.x1 /CLONE=IMAGE:1678879 /UG=Hs.96028 forkhead box D1 AI080288 RP11-79P5.2 213973_at BE646396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646396 /FEA=EST /DB_XREF=gi:9970707 /DB_XREF=est:7e86b08.x1 /CLONE=IMAGE:3292023 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) BE646396 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 213974_at AB033059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033059.1 /DEF=Homo sapiens mRNA for KIAA1233 protein, partial cds. /FEA=mRNA /GEN=KIAA1233 /PROD=KIAA1233 protein /DB_XREF=gi:6330728 /UG=Hs.18705 KIAA1233 protein AB033059 ADAMTS-like 3 ADAMTSL3 57188 NM_207517 /// XM_005272435 /// XM_005272436 /// XM_005272437 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 213975_s_at AV711904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV711904 /FEA=EST /DB_XREF=gi:10731210 /DB_XREF=est:AV711904 /CLONE=DCAAIE08 /UG=Hs.277431 Homo sapiens cDNA: FLJ23356 fis, clone HEP14919 AV711904 lysozyme LYZ 4069 NM_000239 0001764 // neuron migration // inferred from electronic annotation /// 0001895 // retina homeostasis // inferred from expression pattern /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002309 // T cell proliferation involved in immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0002767 // immune response-inhibiting cell surface receptor signaling pathway // non-traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014063 // negative regulation of serotonin secretion // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016998 // cell wall macromolecule catabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0031623 // receptor internalization // traceable author statement /// 0032609 // interferon-gamma production // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032945 // negative regulation of mononuclear cell proliferation // inferred from direct assay /// 0035548 // negative regulation of interferon-beta secretion // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045077 // negative regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0045953 // negative regulation of natural killer cell mediated cytotoxicity // inferred from direct assay /// 0046636 // negative regulation of alpha-beta T cell activation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0072643 // interferon-gamma secretion // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001180 // negative regulation of interleukin-10 secretion // inferred from direct assay /// 2001183 // negative regulation of interleukin-12 secretion // inferred from direct assay /// 2001186 // negative regulation of CD8-positive, alpha-beta T cell activation // inferred from direct assay /// 2001189 // negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from direct assay /// 2001193 // positive regulation of gamma-delta T cell activation involved in immune response // inferred from direct assay /// 2001199 // negative regulation of dendritic cell differentiation // inferred from mutant phenotype /// 2001202 // negative regulation of transforming growth factor-beta secretion // inferred from direct assay /// 2001205 // negative regulation of osteoclast development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003796 // lysozyme activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008157 // protein phosphatase 1 binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030107 // HLA-A specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // inferred from direct assay /// 0032393 // MHC class I receptor activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042288 // MHC class I protein binding // inferred from mutant phenotype /// 0042288 // MHC class I protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 213976_at AA054734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA054734 /FEA=EST /DB_XREF=gi:1545679 /DB_XREF=est:zk68f07.s1 /CLONE=IMAGE:488005 /UG=Hs.23476 Cip1-interacting zinc finger protein AA054734 CDKN1A interacting zinc finger protein 1 CIZ1 25792 NM_001131015 /// NM_001131016 /// NM_001131017 /// NM_001131018 /// NM_001257975 /// NM_001257976 /// NM_012127 /// XM_005251886 /// XM_005251887 /// XM_005251888 /// XM_005251889 /// XM_005251890 /// XM_005251891 /// XM_005251892 /// XM_005251893 /// XM_006717036 /// XM_006717037 /// XM_006717038 /// XM_006717039 /// XM_006717040 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213977_s_at AA054734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA054734 /FEA=EST /DB_XREF=gi:1545679 /DB_XREF=est:zk68f07.s1 /CLONE=IMAGE:488005 /UG=Hs.23476 Cip1-interacting zinc finger protein AA054734 CDKN1A interacting zinc finger protein 1 CIZ1 25792 NM_001131015 /// NM_001131016 /// NM_001131017 /// NM_001131018 /// NM_001257975 /// NM_001257976 /// NM_012127 /// XM_005251886 /// XM_005251887 /// XM_005251888 /// XM_005251889 /// XM_005251890 /// XM_005251891 /// XM_005251892 /// XM_005251893 /// XM_006717036 /// XM_006717037 /// XM_006717038 /// XM_006717039 /// XM_006717040 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from electronic annotation /// 0051658 // maintenance of nucleus location // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213978_at AA338945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA338945 /FEA=EST /DB_XREF=gi:1991203 /DB_XREF=est:EST43994 /UG=Hs.319825 Homo sapiens, clone IMAGE:3616574, mRNA, partial cds AA338945 metastasis suppressor 1-like MTSS1L 92154 NM_138383 /// XM_005256236 /// XM_006721335 /// XM_006721336 0007165 // signal transduction // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 213979_s_at BF984434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF984434 /FEA=EST /DB_XREF=gi:12387246 /DB_XREF=est:602307971F1 /CLONE=IMAGE:4399313 /UG=Hs.239737 C-terminal binding protein 1 BF984434 213980_s_at AA053830 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA053830 /FEA=EST /DB_XREF=gi:1544765 /DB_XREF=est:zf53a05.r1 /CLONE=IMAGE:380624 /UG=Hs.239737 C-terminal binding protein 1 AA053830 C-terminal binding protein 1 CTBP1 1487 NM_001012614 /// NM_001328 /// XM_005272261 /// XM_005272262 /// XM_005272263 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007030 // Golgi organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from mutant phenotype /// 0034401 // regulation of transcription by chromatin organization // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090241 // negative regulation of histone H4 acetylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 213981_at BG054676 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG054676 /FEA=EST /DB_XREF=gi:12511626 /DB_XREF=est:7o46f02.x1 /CLONE=IMAGE:3577107 /UG=Hs.240013 catechol-O-methyltransferase BG054676 catechol-O-methyltransferase COMT 1312 NM_000754 /// NM_001135161 /// NM_001135162 /// NM_007310 /// XM_005261229 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 213982_s_at BG107203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG107203 /FEA=EST /DB_XREF=gi:12601049 /DB_XREF=est:602290933F1 /CLONE=IMAGE:4385577 /UG=Hs.242271 KIAA0471 gene product BG107203 RAB GTPase activating protein 1-like RABGAP1L 9910 NM_001035230 /// NM_001243763 /// NM_001243764 /// NM_001243765 /// NM_014857 /// XM_005245680 /// XM_005245681 /// XM_006711692 /// XM_006711693 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay 213983_s_at AW991219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW991219 /FEA=EST /DB_XREF=gi:8249392 /DB_XREF=est:RDEV128 /UG=Hs.31921 KIAA0648 protein AW991219 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) PDS5A 23244 NM_001100399 /// NM_001100400 /// NM_015200 /// XM_005262652 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213984_at AW991219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW991219 /FEA=EST /DB_XREF=gi:8249392 /DB_XREF=est:RDEV128 /UG=Hs.31921 KIAA0648 protein AW991219 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) PDS5A 23244 NM_001100399 /// NM_001100400 /// NM_015200 /// XM_005262652 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 213985_s_at H45660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H45660 /FEA=EST /DB_XREF=gi:921712 /DB_XREF=est:yn97f04.s1 /CLONE=IMAGE:176383 /UG=Hs.280666 Homo sapiens chromosome 19, cosmid R32184 H45660 transmembrane protein 259 TMEM259 91304 NM_001033026 /// NM_033420 /// XM_005259675 /// XM_005259676 /// XM_005259677 /// XM_005259678 /// XM_005259679 /// XR_244044 /// XR_430159 /// XR_430160 0005737 // cytoplasm // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213986_s_at AI805266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI805266 /FEA=EST /DB_XREF=gi:5391832 /DB_XREF=est:te32c02.x1 /CLONE=IMAGE:2087618 /UG=Hs.280666 Homo sapiens chromosome 19, cosmid R32184 AI805266 transmembrane protein 259 TMEM259 91304 NM_001033026 /// NM_033420 /// XM_005259675 /// XM_005259676 /// XM_005259677 /// XM_005259678 /// XM_005259679 /// XR_244044 /// XR_430159 /// XR_430160 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213987_s_at AA576621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA576621 /FEA=EST /DB_XREF=gi:2353849 /DB_XREF=est:nm74f12.s1 /CLONE=IMAGE:1073999 /UG=Hs.306813 Homo sapiens cDNA: FLJ21847 fis, clone HEP01910 AA576621 cyclin-dependent kinase 13 CDK13 8621 NM_003718 /// NM_031267 0000380 // alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0000380 // alternative mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 213988_s_at BE971383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE971383 /FEA=EST /DB_XREF=gi:10584719 /DB_XREF=est:601651561F1 /CLONE=IMAGE:3934935 /UG=Hs.28491 spermidinespermine N1-acetyltransferase BE971383 spermidine/spermine N1-acetyltransferase 1 SAT1 6303 NM_002970 /// NR_027783 0001525 // angiogenesis // inferred from expression pattern /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009447 // putrescine catabolic process // inferred from electronic annotation /// 0032918 // spermidine acetylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004145 // diamine N-acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019809 // spermidine binding // inferred from electronic annotation 213989_x_at AB004853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB004853.1 /DEF=Homo sapiens mRNA expressed in neuron, clone IMAGE:546180. /FEA=mRNA /DB_XREF=gi:3702687 /UG=Hs.50748 chromosome 21 open reading frame 18 AB004853 SET domain containing 4 SETD4 54093 NM_001007258 /// NM_001007259 /// NM_001007260 /// NM_001007261 /// NM_001007262 /// NM_001286752 /// NM_017438 /// NR_040087 /// XM_005260999 /// XM_005261000 /// XM_005261001 /// XM_005261003 /// XM_006724021 /// XM_006724022 /// XM_006724023 /// XR_244283 /// XR_430350 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 213990_s_at BF056517 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056517 /FEA=EST /DB_XREF=gi:10810413 /DB_XREF=est:7k06c06.x1 /CLONE=IMAGE:3443339 /UG=Hs.32539 KIAA1264 protein BF056517 p21 protein (Cdc42/Rac)-activated kinase 7 PAK7 57144 NM_020341 /// NM_177990 /// XM_005260766 /// XM_006723597 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 213991_s_at BF940710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF940710 /FEA=EST /DB_XREF=gi:12358030 /DB_XREF=est:nae24b08.x1 /CLONE=IMAGE:3435999 /UG=Hs.40968 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 BF940710 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 HS3ST1 9957 NM_005114 /// XM_005248221 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005796 // Golgi lumen // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0008146 // sulfotransferase activity // traceable author statement /// 0008467 // [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity // inferred from electronic annotation 213992_at AI889941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI889941 /FEA=EST /DB_XREF=gi:5595105 /DB_XREF=est:wm65d06.x1 /CLONE=IMAGE:2440811 /UG=Hs.408 collagen, type IV, alpha 6 AI889941 collagen, type IV, alpha 6 COL4A6 1288 NM_001287758 /// NM_001287759 /// NM_001287760 /// NM_001847 /// NM_033641 /// XM_006724617 /// XM_006724618 0007155 // cell adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005198 // structural molecule activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation 213993_at AI885290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885290 /FEA=EST /DB_XREF=gi:5590454 /DB_XREF=est:wl92a04.x1 /CLONE=IMAGE:2432334 /UG=Hs.5378 spondin 1, (f-spondin) extracellular matrix protein AI885290 spondin 1, extracellular matrix protein SPON1 10418 NM_006108 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 213994_s_at AI885290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885290 /FEA=EST /DB_XREF=gi:5590454 /DB_XREF=est:wl92a04.x1 /CLONE=IMAGE:2432334 /UG=Hs.5378 spondin 1, (f-spondin) extracellular matrix protein AI885290 spondin 1, extracellular matrix protein SPON1 10418 NM_006108 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 213995_at AW195882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW195882 /FEA=EST /DB_XREF=gi:6475112 /DB_XREF=est:xn86c10.x1 /CLONE=IMAGE:2701362 /UG=Hs.56155 hypothetical protein AW195882 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) ATP5S 27109 NM_001003803 /// NM_001003805 /// NM_015684 /// NR_033761 /// XM_005267537 /// XM_005267538 /// XM_005267539 /// XR_245682 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 213996_at NM_013313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_013313.1 /DEF=Homo sapiens hypothetical protein (AF060862), mRNA. /FEA=CDS /GEN=AF060862 /PROD=hypothetical protein /DB_XREF=gi:9558720 /UG=Hs.71791 hypothetical protein /FL=gb:NM_013313.1 NM_013313 yippee-like 1 (Drosophila) YPEL1 29799 NM_013313 /// XM_006724237 /// XM_006724238 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 213997_at AB011146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011146.1 /DEF=Homo sapiens mRNA for KIAA0574 protein, partial cds. /FEA=mRNA /GEN=KIAA0574 /PROD=KIAA0574 protein /DB_XREF=gi:3043671 /UG=Hs.7132 KIAA0574 protein AB011146 family with sequence similarity 189, member A1 FAM189A1 23359 NM_015307 /// XM_005254261 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 213998_s_at AW188131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188131 /FEA=EST /DB_XREF=gi:6462567 /DB_XREF=est:xj92f11.x1 /CLONE=IMAGE:2664717 /UG=Hs.6179 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 17 (72kD) AW188131 DEAD (Asp-Glu-Ala-Asp) box helicase 17 DDX17 10521 NM_001098504 /// NM_001098505 /// NM_006386 /// NM_030881 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 213999_at BE999993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE999993 /FEA=EST /DB_XREF=gi:10700269 /DB_XREF=est:7h15e08.x1 /CLONE=IMAGE:3316070 /UG=Hs.66309 Homo sapiens, Similar to RIKEN cDNA 2310034L04 gene, clone MGC:11061, mRNA, complete cds BE999993 Yip1 domain family, member 4 YIPF4 84272 NM_032312 /// XM_005264599 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 214000_s_at AI744627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744627 /FEA=EST /DB_XREF=gi:5113004 /DB_XREF=est:wg04g05.x1 /CLONE=IMAGE:2364152 /UG=Hs.82280 regulator of G-protein signalling 10 AI744627 regulator of G-protein signaling 10 RGS10 6001 NM_001005339 /// NM_002925 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded 214001_x_at AW302047 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW302047 /FEA=EST /DB_XREF=gi:6711724 /DB_XREF=est:xr52f08.x1 /CLONE=IMAGE:2763783 /UG=Hs.76230 ribosomal protein S10 AW302047 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214002_at AA419227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA419227 /FEA=EST /DB_XREF=gi:2078957 /DB_XREF=est:zv35a09.s1 /CLONE=IMAGE:755608 /UG=Hs.77385 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle AA419227 myosin, light chain 6, alkali, smooth muscle and non-muscle MYL6 4637 NM_021019 /// NM_079423 /// NM_079425 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071564 // npBAF complex // inferred from electronic annotation /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from electronic annotation /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0031492 // nucleosomal DNA binding // inferred from direct assay 214003_x_at BF184532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF184532 /FEA=EST /DB_XREF=gi:11062829 /DB_XREF=est:601842837F1 /CLONE=IMAGE:4063593 /UG=Hs.8102 ribosomal protein S20 BF184532 ribosomal protein S20 /// small nucleolar RNA, C/D box 54 RPS20 /// SNORD54 6224 /// 26795 NM_001023 /// NM_001146227 /// NR_002437 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214004_s_at AI806207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806207 /FEA=EST /DB_XREF=gi:5392773 /DB_XREF=est:wf26d03.x1 /CLONE=IMAGE:2356709 /UG=Hs.79025 KIAA0096 protein AI806207 vestigial-like family member 4 VGLL4 9686 NM_001128219 /// NM_001128220 /// NM_001128221 /// NM_001284390 /// NM_001284391 /// NM_014667 /// XM_006713423 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 214005_at BE326952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE326952 /FEA=EST /DB_XREF=gi:9200728 /DB_XREF=est:hr68a04.x1 /CLONE=IMAGE:3133614 /UG=Hs.77719 gamma-glutamyl carboxylase BE326952 gamma-glutamyl carboxylase GGCX 2677 NM_000821 /// NM_001142269 /// XM_005264259 0006464 // cellular protein modification process // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008488 // gamma-glutamyl carboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 214006_s_at BE326952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE326952 /FEA=EST /DB_XREF=gi:9200728 /DB_XREF=est:hr68a04.x1 /CLONE=IMAGE:3133614 /UG=Hs.77719 gamma-glutamyl carboxylase BE326952 gamma-glutamyl carboxylase GGCX 2677 NM_000821 /// NM_001142269 /// XM_005264259 0006464 // cellular protein modification process // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008488 // gamma-glutamyl carboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 214007_s_at AW665024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW665024 /FEA=EST /DB_XREF=gi:7457569 /DB_XREF=est:hi86c09.x1 /CLONE=IMAGE:2979184 /UG=Hs.82643 protein tyrosine kinase 9 AW665024 twinfilin actin-binding protein 1 TWF1 5756 NM_001242397 /// NM_002822 /// NM_198974 /// NR_073472 /// NR_073473 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0043538 // regulation of actin phosphorylation // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity 214008_at N25562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N25562 /FEA=EST /DB_XREF=gi:1139910 /DB_XREF=est:yx76h01.s1 /CLONE=IMAGE:267697 /UG=Hs.82643 protein tyrosine kinase 9 N25562 twinfilin actin-binding protein 1 TWF1 5756 NM_001242397 /// NM_002822 /// NM_198974 /// NR_073472 /// NR_073473 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0043538 // regulation of actin phosphorylation // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity 214009_at R10150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R10150 /FEA=EST /DB_XREF=gi:762106 /DB_XREF=est:yf31g02.s1 /CLONE=IMAGE:128498 /UG=Hs.88764 male-specific lethal-3 (Drosophila)-like 1 R10150 male-specific lethal 3 homolog (Drosophila) MSL3 10943 NM_001193270 /// NM_001282174 /// NM_006800 /// NM_078628 /// NM_078629 /// NM_078630 /// XM_005274440 /// XM_006724461 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0072487 // MSL complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0035064 // methylated histone binding // inferred from direct assay 214010_s_at R50094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R50094 /FEA=EST /DB_XREF=gi:811996 /DB_XREF=est:yj59g12.s1 /CLONE=IMAGE:153094 /UG=Hs.91471 ATPase, Class II, type 9B R50094 ATPase, class II, type 9B ATP9B 374868 NM_198531 /// XM_005266690 /// XM_005266691 /// XM_005266692 /// XM_005266693 /// XM_005266694 /// XM_005266695 /// XM_006722447 /// XM_006722448 /// XM_006722449 /// XM_006722450 /// XR_245458 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0015917 // aminophospholipid transport // non-traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0072600 // establishment of protein localization to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015247 // aminophospholipid transporter activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214011_s_at BE314601 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE314601 /FEA=EST /DB_XREF=gi:9135934 /DB_XREF=est:601149573F1 /CLONE=IMAGE:3502002 /UG=Hs.279918 hypothetical protein BE314601 NOP16 nucleolar protein NOP16 51491 NM_001256539 /// NM_001256540 /// NM_001291305 /// NM_001291306 /// NM_001291307 /// NM_001291308 /// NM_016391 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 214012_at BE551138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551138 /FEA=EST /DB_XREF=gi:9792830 /DB_XREF=est:7b55a07.x1 /CLONE=IMAGE:3232116 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator BE551138 endoplasmic reticulum aminopeptidase 1 ERAP1 51752 NM_001040458 /// NM_001198541 /// NM_016442 /// XM_005272015 /// XM_005272016 0001525 // angiogenesis // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009617 // response to bacterium // inferred from expression pattern /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // non-traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement /// 0045088 // regulation of innate immune response // non-traceable author statement /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214013_s_at BE675153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675153 /FEA=EST /DB_XREF=gi:10035694 /DB_XREF=est:7f03d07.x1 /CLONE=IMAGE:3293581 /UG=Hs.278586 KIAA1108 protein BE675153 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 TBC1D1 23216 NM_001253912 /// NM_001253913 /// NM_001253914 /// NM_001253915 /// NM_015173 /// XM_005262646 /// XM_005262647 /// XM_005262648 /// XM_005262649 /// XM_005262651 /// XM_006713999 /// XM_006714000 /// XM_006714001 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005097 // Rab GTPase activator activity // inferred from electronic annotation 214014_at W81196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W81196 /FEA=EST /DB_XREF=gi:1392235 /DB_XREF=est:zd85d03.s1 /CLONE=IMAGE:347429 /UG=Hs.12289 Cdc42 effector protein 2 W81196 CDC42 effector protein (Rho GTPase binding) 2 CDC42EP2 10435 NM_006779 0007015 // actin filament organization // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031334 // positive regulation of protein complex assembly // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0001515 // opioid peptide activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from physical interaction 214015_at AI968839 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI968839 /FEA=EST /DB_XREF=gi:5765657 /DB_XREF=est:wt93f02.x1 /CLONE=IMAGE:2515035 /UG=Hs.104481 Nck, Ash and phospholipase C binding protein AI968839 suppressor of cytokine signaling 7 SOCS7 30837 NM_014598 /// XM_005257264 /// XM_005257265 /// XM_005276891 /// XM_005276892 /// XR_243651 /// XR_254229 /// XR_429888 /// XR_430781 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // non-traceable author statement 214016_s_at AL558875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL558875 /FEA=EST /DB_XREF=gi:12903824 /DB_XREF=est:AL558875 /CLONE=CS0DJ015YJ02 (5 prime) /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) AL558875 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214017_s_at AA039439 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA039439 /FEA=EST /DB_XREF=gi:1515780 /DB_XREF=est:zk39a11.s1 /CLONE=IMAGE:485180 /UG=Hs.151706 KIAA0134 gene product AA039439 DEAH (Asp-Glu-Ala-His) box polypeptide 34 DHX34 9704 NM_014681 /// NM_194428 /// XM_005259443 /// XR_243974 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214018_at AI203397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI203397 /FEA=EST /DB_XREF=gi:3756003 /DB_XREF=est:qr30d04.x1 /CLONE=IMAGE:1942375 /UG=Hs.126076 Glutamate receptor interacting protein AI203397 glutamate receptor interacting protein 1 GRIP1 23426 NM_001178074 /// NM_021150 /// XM_005268754 /// XM_005268755 /// XM_005268756 /// XM_005268757 /// XM_005268758 /// XM_005268759 0007268 // synaptic transmission // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0050681 // androgen receptor binding // non-traceable author statement 214019_at Z23022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z23022.1 /DEF=H.sapiens of BCL1 mRNA encoding cyclin. /FEA=mRNA /GEN=BCL1 /PROD=cyclin /DB_XREF=gi:312911 /UG=Hs.274766 B-cell CLLlymphoma 1 Z23022 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 214020_x_at BE138575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE138575 /FEA=EST /DB_XREF=gi:8601075 /DB_XREF=est:xr77e12.x2 /CLONE=IMAGE:2766190 /UG=Hs.149846 integrin, beta 5 BE138575 integrin, beta 5 ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214021_x_at AI335208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI335208 /FEA=EST /DB_XREF=gi:4072135 /DB_XREF=est:ta93a09.x1 /CLONE=IMAGE:2051608 /UG=Hs.149846 integrin, beta 5 AI335208 integrin, beta 5 ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214022_s_at AA749101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA749101 /FEA=EST /DB_XREF=gi:2789059 /DB_XREF=est:ny11d02.s1 /CLONE=IMAGE:1271427 /UG=Hs.146360 interferon induced transmembrane protein 1 (9-27) AA749101 interferon induced transmembrane protein 1 IFITM1 8519 NM_003641 0001503 // ossification // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214023_x_at AL533838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL533838 /FEA=EST /DB_XREF=gi:12797331 /DB_XREF=est:AL533838 /CLONE=CS0DF002YB07 (3 prime) /UG=Hs.179661 tubulin, beta polypeptide AL533838 tubulin, beta 2B class IIb TUBB2B 347733 NM_178012 0001764 // neuron migration // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 214024_s_at AA631156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA631156 /FEA=EST /DB_XREF=gi:2553767 /DB_XREF=est:nq80a01.s1 /CLONE=IMAGE:1158600 /UG=Hs.153910 DiGeorge syndrome critical region gene 6 AA631156 DiGeorge syndrome critical region gene 6-like DGCR6L 85359 NM_033257 0005634 // nucleus // inferred from electronic annotation 214025_at AI922937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922937 /FEA=EST /DB_XREF=gi:5658987 /DB_XREF=est:wn66d06.x1 /CLONE=IMAGE:2450411 /UG=Hs.155049 hypothetical protein FLJ11282 AI922937 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214026_s_at AI860246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI860246 /FEA=EST /DB_XREF=gi:5513862 /DB_XREF=est:wk99e10.x1 /CLONE=IMAGE:2423562 /UG=Hs.173108 Homo sapiens cDNA: FLJ21897 fis, clone HEP03447, highly similar to AF052178 Homo sapiens clone 24523 mRNA sequence AI860246 sprouty-related, EVH1 domain containing 2 SPRED2 200734 NM_001128210 /// NM_181784 /// XM_005264200 /// XM_005264201 /// XM_005264202 /// XM_006711966 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0090311 // regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation 0005173 // stem cell factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity 214027_x_at AA889653 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA889653 /FEA=EST /DB_XREF=gi:3016532 /DB_XREF=est:ak50c11.s1 /CLONE=IMAGE:1409396 /UG=Hs.171185 transcription factor (p38 interacting protein) AA889653 desmin /// suppressor of Ty 20 homolog (S. cerevisiae) DES /// SUPT20H 1674 /// 55578 NM_001014286 /// NM_001278480 /// NM_001278481 /// NM_001278482 /// NM_001927 /// NM_017569 /// XM_005266447 /// XM_005266448 /// XM_005266449 /// XM_005266450 /// XM_005266451 /// XM_005266452 /// XM_005266453 /// XM_005266454 /// XM_005266455 /// XM_005266456 /// XM_005266457 /// XM_005266458 /// XM_005266460 /// XM_005266461 /// XM_005266462 /// XM_005266464 /// XM_005266465 /// XM_005266466 /// XM_005266467 /// XM_005266468 0006325 // chromatin organization // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000124 // SAGA complex // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 214028_x_at AU156998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU156998 /FEA=EST /DB_XREF=gi:11018519 /DB_XREF=est:AU156998 /CLONE=PLACE1005639 /UG=Hs.1975 hypothetical protein FLJ21007 AU156998 tudor domain containing 3 TDRD3 81550 NM_001146070 /// NM_001146071 /// NM_030794 /// XM_005266556 /// XM_005266557 /// XM_005266558 /// XM_005266560 /// XR_429220 /// XR_429221 0016568 // chromatin modification // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 214029_at AI435954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI435954 /FEA=EST /DB_XREF=gi:4306795 /DB_XREF=est:th80d08.x1 /CLONE=IMAGE:2124975 /UG=Hs.20707 hypothetical protein R31240_1 AI435954 solute carrier family 25, member 42 SLC25A42 284439 NM_178526 /// XM_005259861 /// XM_005259862 0008152 // metabolic process // inferred from direct assay /// 0015866 // ADP transport // inferred from direct assay /// 0015867 // ATP transport // inferred from direct assay /// 0035349 // coenzyme A transmembrane transport // inferred from direct assay /// 0080121 // AMP transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005347 // ATP transmembrane transporter activity // inferred from direct assay /// 0015217 // ADP transmembrane transporter activity // inferred from direct assay /// 0015228 // coenzyme A transmembrane transporter activity // inferred from direct assay /// 0043262 // adenosine-diphosphatase activity // inferred from direct assay /// 0080122 // AMP transmembrane transporter activity // inferred from direct assay 214030_at BE501352 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE501352 /FEA=EST /DB_XREF=gi:9703760 /DB_XREF=est:7a41e05.x1 /CLONE=IMAGE:3221312 /UG=Hs.23294 ESTs, Weakly similar to T15138 hypothetical protein T28F2.4 - Caenorhabditis elegans C.elegans BE501352 beta-gamma crystallin domain containing 3 CRYBG3 131544 NM_153605 /// XM_005247117 /// XR_241467 214031_s_at AI920979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI920979 /FEA=EST /DB_XREF=gi:5656943 /DB_XREF=est:wo16h11.x1 /CLONE=IMAGE:2455557 /UG=Hs.23881 keratin 7 AI920979 keratin 7 KRT7 3855 NM_005556 /// XR_245927 0016032 // viral process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214032_at AI817942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817942 /FEA=EST /DB_XREF=gi:5437110 /DB_XREF=est:wk41f07.x1 /CLONE=IMAGE:2417989 /UG=Hs.234569 zeta-chain (TCR) associated protein kinase (70 kD) AI817942 zeta-chain (TCR) associated protein kinase 70kDa ZAP70 7535 NM_001079 /// NM_207519 /// XM_005264015 /// XM_006712728 /// XM_006712729 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006955 // immune response // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0030217 // T cell differentiation // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0043366 // beta selection // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from direct assay /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0070489 // T cell aggregation // traceable author statement /// 0072678 // T cell migration // traceable author statement 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214033_at AI084637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI084637 /FEA=EST /DB_XREF=gi:3423060 /DB_XREF=est:oz78d08.x1 /CLONE=IMAGE:1681455 /UG=Hs.274260 ATP-binding cassette, sub-family C (CFTRMRP), member 6 AI084637 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 /// ATP-binding cassette, sub-family C, member 6 pseudogene 1 (functional) /// ATP-binding cassette, sub-family C, member 6 pseudogene 2 /// multidrug resistance-associated protein 6-like ABCC6 /// ABCC6P1 /// ABCC6P2 /// LOC101930322 368 /// 653190 /// 730013 /// 101930322 NM_001079528 /// NM_001171 /// NR_003569 /// NR_023387 /// XM_005255310 /// XM_005276048 /// XM_006725193 /// XM_006725194 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 214034_at AB011097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011097.1 /DEF=Homo sapiens mRNA for KIAA0525 protein, partial cds. /FEA=mRNA /GEN=KIAA0525 /PROD=KIAA0525 protein /DB_XREF=gi:3043573 /UG=Hs.247043 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator AB011097 endoplasmic reticulum aminopeptidase 1 ERAP1 51752 NM_001040458 /// NM_001198541 /// NM_016442 /// XM_005272015 /// XM_005272016 0001525 // angiogenesis // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0009617 // response to bacterium // inferred from expression pattern /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // non-traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement /// 0045088 // regulation of innate immune response // non-traceable author statement /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214035_x_at AA308853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA308853 /FEA=EST /DB_XREF=gi:1961191 /DB_XREF=est:EST179659 /UG=Hs.251928 nuclear pore complex interacting protein AA308853 GPS, PLAT and transmembrane domain-containing protein LOC399491 399491 XR_248294 /// XR_430728 /// XR_433252 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from electronic annotation /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // /// 0050982 // detection of mechanical stimulus // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from electronic annotation /// 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 214036_at BE464799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE464799 /FEA=EST /DB_XREF=gi:9510493 /DB_XREF=est:hs87a06.x1 /CLONE=IMAGE:3144178 /UG=Hs.27342 ESTs BE464799 ephrin-A5 EFNA5 1946 NM_001962 /// XM_006714565 0006915 // apoptotic process // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 214037_s_at BF224247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224247 /FEA=EST /DB_XREF=gi:11131508 /DB_XREF=est:7q85b07.x1 /CLONE=IMAGE:3705156 /UG=Hs.26333 JM1 protein BF224247 coiled-coil domain containing 22 CCDC22 28952 NM_014008 /// XM_005272599 /// XR_430506 0005515 // protein binding // inferred from electronic annotation 214038_at AI984980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984980 /FEA=EST /DB_XREF=gi:5812257 /DB_XREF=est:wr88g11.x1 /CLONE=IMAGE:2494820 /UG=Hs.271387 small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2) /FL=gb:NM_005623.1 AI984980 chemokine (C-C motif) ligand 8 CCL8 6355 NM_005623 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009615 // response to virus // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from direct assay 214039_s_at T15777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T15777 /FEA=EST /DB_XREF=gi:517939 /DB_XREF=est:IB1875 /UG=Hs.296398 Homo sapiens mRNA; cDNA DKFZp586E1124 (from clone DKFZp586E1124); complete cds T15777 lysosomal protein transmembrane 4 beta LAPTM4B 55353 NM_018407 0006810 // transport // inferred from electronic annotation 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214040_s_at BE675337 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675337 /FEA=EST /DB_XREF=gi:10035878 /DB_XREF=est:7f07c05.x1 /CLONE=IMAGE:3293960 /UG=Hs.290070 gelsolin (amyloidosis, Finnish type) BE675337 gelsolin GSN 2934 NM_000177 /// NM_001127662 /// NM_001127663 /// NM_001127664 /// NM_001127665 /// NM_001127666 /// NM_001127667 /// NM_001258029 /// NM_001258030 /// NM_198252 /// XM_005251940 /// XM_005251943 /// XM_005251944 /// XM_005251945 /// XM_006717075 /// XM_006717076 /// XM_006717077 /// XM_006717078 /// XM_006717079 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051014 // actin filament severing // inferred from direct assay /// 0051014 // actin filament severing // inferred from sequence or structural similarity /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214041_x_at BE857772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE857772 /FEA=EST /DB_XREF=gi:10372131 /DB_XREF=est:7d62a11.x1 /CLONE=IMAGE:3251804 /UG=Hs.5566 ribosomal protein L37a BE857772 ribosomal protein L37a RPL37A 6168 NM_000998 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214042_s_at AW071997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW071997 /FEA=EST /DB_XREF=gi:6026995 /DB_XREF=est:ws57f09.x1 /CLONE=IMAGE:2501321 /UG=Hs.326249 Homo sapiens mRNA; cDNA DKFZp586E0524 (from clone DKFZp586E0524) AW071997 ribosomal protein L22 RPL22 6146 NM_000983 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214043_at BF062299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062299 /FEA=EST /DB_XREF=gi:10821197 /DB_XREF=est:7k76c03.x1 /CLONE=IMAGE:3481325 /UG=Hs.323079 Homo sapiens mRNA; cDNA DKFZp564P116 (from clone DKFZp564P116) BF062299 protein tyrosine phosphatase, receptor type, D PTPRD 5789 NM_001040712 /// NM_001171025 /// NM_002839 /// NM_130391 /// NM_130392 /// NM_130393 /// XM_006716813 /// XM_006716814 /// XM_006716815 /// XM_006716816 /// XM_006716817 /// XM_006716818 /// XM_006716819 /// XM_006716820 /// XM_006716821 /// XM_006716822 /// XM_006716823 /// XM_006716824 /// XM_006716825 /// XM_006716826 /// XM_006716827 /// XM_006716828 /// XM_006716829 /// XM_006716830 /// XM_006716831 /// XM_006716832 /// XM_006716833 /// XM_006716834 /// XM_006716835 /// XM_006716836 /// XM_006716837 /// XM_006716838 /// XM_006716839 0006470 // protein dephosphorylation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // non-traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 214044_at BE968750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE968750 /FEA=EST /DB_XREF=gi:10579455 /DB_XREF=est:601649921F1 /CLONE=IMAGE:3933773 /UG=Hs.332699 Homo sapiens ryanodine receptor 2 (cardiac) (RYR2), mRNA BE968750 ryanodine receptor 2 (cardiac) RYR2 6262 NM_001035 /// XM_006711802 /// XM_006711803 /// XM_006711804 /// XM_006711805 /// XM_006711806 /// XM_006711807 /// XM_006711808 /// XM_006711809 /// XM_006711810 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003220 // left ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0003300 // cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from mutant phenotype /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051284 // positive regulation of sequestering of calcium ion // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from direct assay /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072599 // establishment of protein localization to endoplasmic reticulum // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086029 // Purkinje myocyte to ventricular cardiac muscle cell signaling // inferred from sequence or structural similarity /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 0086094 // positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0097050 // type B pancreatic cell apoptotic process // inferred from mutant phenotype /// 1901896 // positive regulation of calcium-transporting ATPase activity // inferred from direct assay 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0034704 // calcium channel complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from electronic annotation /// 0043924 // suramin binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0048763 // calcium-induced calcium release activity // inferred from direct assay 214045_at BF056778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056778 /FEA=EST /DB_XREF=gi:10810674 /DB_XREF=est:7k09c01.x1 /CLONE=IMAGE:3443712 /UG=Hs.53531 lipoic acid synthetase BF056778 lipoic acid synthetase LIAS 11019 NM_001278590 /// NM_001278591 /// NM_001278592 /// NM_006859 /// NM_194451 /// XM_006713990 0001843 // neural tube closure // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009107 // lipoate biosynthetic process // inferred from sequence or structural similarity /// 0009249 // protein lipoylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation /// 0016992 // lipoate synthase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 214046_at AA017721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA017721 /FEA=EST /DB_XREF=gi:1479910 /DB_XREF=est:ze39f11.s1 /CLONE=IMAGE:361389 /UG=Hs.49117 Homo sapiens mRNA; cDNA DKFZp564N1662 (from clone DKFZp564N1662) AA017721 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) FUT9 10690 NM_006581 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017083 // 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 214047_s_at AI913365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI913365 /FEA=EST /DB_XREF=gi:5633220 /DB_XREF=est:wa11d06.x1 /CLONE=IMAGE:2297771 /UG=Hs.35947 methyl-CpG binding domain protein 4 AI913365 methyl-CpG binding domain protein 4 MBD4 8930 NM_001276270 /// NM_001276271 /// NM_001276272 /// NM_001276273 /// NM_003925 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 214048_at AI913365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI913365 /FEA=EST /DB_XREF=gi:5633220 /DB_XREF=est:wa11d06.x1 /CLONE=IMAGE:2297771 /UG=Hs.35947 methyl-CpG binding domain protein 4 AI913365 methyl-CpG binding domain protein 4 MBD4 8930 NM_001276270 /// NM_001276271 /// NM_001276272 /// NM_001276273 /// NM_003925 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 214049_x_at AI829961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI829961 /FEA=EST /DB_XREF=gi:5450632 /DB_XREF=est:wj85a07.x1 /CLONE=IMAGE:2409588 /UG=Hs.36972 CD7 antigen (p41) AI829961 CD7 molecule CD7 924 NM_006137 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214050_at AI694317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694317 /FEA=EST /DB_XREF=gi:4971657 /DB_XREF=est:wd45d06.x1 /CLONE=IMAGE:2331083 /UG=Hs.86041 CGG triplet repeat binding protein 1 AI694317 214051_at BF677486 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF677486 /FEA=EST /DB_XREF=gi:11951381 /DB_XREF=est:602085745F1 /CLONE=IMAGE:4249834 /UG=Hs.56145 thymosin, beta, identified in neuroblastoma cells BF677486 thymosin beta 15a /// thymosin beta 15B TMSB15A /// TMSB15B 11013 /// 286527 NM_021992 /// NM_194324 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042989 // sequestering of actin monomers // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 214052_x_at AW301305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301305 /FEA=EST /DB_XREF=gi:6710982 /DB_XREF=est:xs75a07.x1 /CLONE=IMAGE:2775444 /UG=Hs.69559 KIAA1096 protein AW301305 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214053_at AW772192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW772192 /FEA=EST /DB_XREF=gi:7704256 /DB_XREF=est:hn69f02.x1 /CLONE=IMAGE:3033147 /UG=Hs.7888 Homo sapiens clone 23736 mRNA sequence AW772192 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 ERBB4 2066 NM_001042599 /// NM_005235 /// XM_005246375 /// XM_005246376 /// XM_005246377 /// XM_006712364 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021551 // central nervous system morphogenesis // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060644 // mammary gland epithelial cell differentiation // inferred from sequence or structural similarity /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061026 // cardiac muscle tissue regeneration // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000366 // positive regulation of STAT protein import into nucleus // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 214054_at AI828929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI828929 /FEA=EST /DB_XREF=gi:5449600 /DB_XREF=est:wj37g10.x1 /CLONE=IMAGE:2405058 /UG=Hs.71215 docking protein 2, 56kD /FL=gb:AF034970.1 gb:NM_003974.1 AI828929 docking protein 2, 56kDa DOK2 9046 NM_003974 /// NM_201349 /// XM_005273680 /// XM_005273681 /// XM_006716411 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005829 // cytosol // traceable author statement 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 214055_x_at AW238632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW238632 /FEA=EST /DB_XREF=gi:6571021 /DB_XREF=est:xp29d03.x1 /CLONE=IMAGE:2741765 /UG=Hs.69559 KIAA1096 protein AW238632 proline-rich coiled-coil 2C PRRC2C 23215 NM_015172 /// XM_005245015 /// XM_005245016 /// XM_005245017 /// XM_005245018 /// XM_005245019 /// XM_005245020 /// XM_005245022 /// XM_005245023 /// XM_005245024 /// XM_005245025 /// XM_005245026 /// XM_005245027 /// XM_005245028 /// XM_005245029 /// XM_005245030 /// XM_006711238 /// XM_006711239 0016020 // membrane // inferred from direct assay 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214056_at BF981280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF981280 /FEA=EST /DB_XREF=gi:12384092 /DB_XREF=est:602308517F1 /CLONE=IMAGE:4399756 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) BF981280 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0034097 // response to cytokine // inferred from direct assay /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 214057_at H71805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H71805 /FEA=EST /DB_XREF=gi:1043621 /DB_XREF=est:ys05h09.s1 /CLONE=IMAGE:213953 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) H71805 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0034097 // response to cytokine // inferred from direct assay /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 214058_at M19720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M19720 /DEF=Human L-myc protein gene, complete cds /FEA=mRNA_2 /DB_XREF=gi:188906 /UG=Hs.92137 v-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived M19720 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog MYCL 4610 NM_001033081 /// NM_001033082 /// NM_005376 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 214059_at BE049439 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE049439 /FEA=EST /DB_XREF=gi:8366494 /DB_XREF=est:xw86e11.x1 /CLONE=IMAGE:2834924 /UG=Hs.82316 interferon-induced, hepatitis C-associated microtubular aggregate protein (44kD) BE049439 interferon-induced protein 44 IFI44 10561 NM_006417 /// XM_005270380 /// XR_246226 /// XR_426586 0009615 // response to virus // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 214060_at BE220360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE220360 /FEA=EST /DB_XREF=gi:8907678 /DB_XREF=est:hv71c07.x1 /CLONE=IMAGE:3178860 /UG=Hs.923 single-stranded DNA-binding protein BE220360 single-stranded DNA binding protein 1, mitochondrial SSBP1 6742 NM_001256510 /// NM_001256511 /// NM_001256512 /// NM_001256513 /// NM_003143 /// NR_046269 /// XM_005250048 /// XM_005250049 /// XM_005250050 /// XM_005250051 0006260 // DNA replication // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214061_at AI017564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI017564 /FEA=EST /DB_XREF=gi:3231900 /DB_XREF=est:ou23e03.x1 /CLONE=IMAGE:1627132 /UG=Hs.95631 Human normal keratinocyte mRNA AI017564 TBC1 domain family, member 31 TBC1D31 93594 NM_001145088 /// NM_145647 /// XM_005251102 /// XM_005251103 /// XM_005251104 /// XM_005251105 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214062_x_at AI684894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI684894 /FEA=EST /DB_XREF=gi:4896188 /DB_XREF=est:wa86h04.x1 /CLONE=IMAGE:2303095 /UG=Hs.9731 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta AI684894 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta NFKBIB 4793 NM_001001716 /// NM_001243116 /// NM_002503 /// NR_040515 /// XM_006723226 /// XM_006723227 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214063_s_at AI073407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073407 /FEA=EST /DB_XREF=gi:3400051 /DB_XREF=est:ov46b06.x1 /CLONE=IMAGE:1640339 /UG=Hs.284176 transferrin AI073407 transferrin TF 7018 NM_001063 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030120 // vesicle coat // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097433 // dense body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214064_at AI073407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073407 /FEA=EST /DB_XREF=gi:3400051 /DB_XREF=est:ov46b06.x1 /CLONE=IMAGE:1640339 /UG=Hs.284176 transferrin AI073407 transferrin TF 7018 NM_001063 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030120 // vesicle coat // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097433 // dense body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214065_s_at BG251252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG251252 /FEA=EST /DB_XREF=gi:12761068 /DB_XREF=est:602365878F1 /CLONE=IMAGE:4474147 /UG=Hs.129867 DNA-dependent protein kinase catalytic subunit-interacting protein 2 BG251252 calcium and integrin binding family member 2 CIB2 10518 NM_001271888 /// NM_001271889 /// NM_006383 /// XM_005254126 /// XM_005254128 /// XM_006720373 /// XM_006720374 0016310 // phosphorylation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214066_x_at AA565715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA565715 /FEA=EST /DB_XREF=gi:2337354 /DB_XREF=est:nj23e10.s1 /CLONE=IMAGE:993354 /UG=Hs.256747 sperm associated antigen 8 AA565715 natriuretic peptide receptor 2 NPR2 4882 NM_000907 /// NM_003995 /// XM_005251478 /// XM_005251479 /// XM_006716778 0001503 // ossification // inferred from electronic annotation /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0008217 // regulation of blood pressure // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from expression pattern 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 214067_at AL031709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031709 /DEF=Human DNA sequence from clone 316G12 on chromosome 16. Contains the gene for C2 domain protein KIAA0734, the gene for a novel protein similar to predicted yeast, worm and archae-bacterial proteins, a novel gene and the 3 part of the gene for a no... /FEA=mRNA_4 /DB_XREF=gi:5050957 /UG=Hs.101516 BAI1-associated protein 3 AL031709 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) TSR3 115939 NM_001001410 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 214068_at AF070610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070610.1 /DEF=Homo sapiens clone 24505 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387992 /UG=Hs.100543 Homo sapiens clone 24505 mRNA sequence AF070610 brain expressed, associated with NEDD4, 1 BEAN1 146227 NM_001136106 /// NM_001178020 /// NM_001197224 /// NM_001197225 /// XM_006721144 0008219 // cell death // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214069_at AA865601 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA865601 /FEA=EST /DB_XREF=gi:2957877 /DB_XREF=est:og93e03.s1 /CLONE=IMAGE:1455868 /UG=Hs.126261 Homo sapiens Chromosome 16 BAC clone CIT987SK-A-923A4 AA865601 acyl-CoA synthetase medium-chain family member 2A /// acyl-CoA synthetase medium-chain family member 2B ACSM2A /// ACSM2B 123876 /// 348158 NM_001010845 /// NM_001105069 /// NM_182617 /// XM_005255093 /// XM_005255304 /// XR_243259 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0036112 // medium-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0042593 // glucose homeostasis // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070328 // triglyceride homeostasis // non-traceable author statement 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from direct assay /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 214070_s_at AW006935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006935 /FEA=EST /DB_XREF=gi:5855713 /DB_XREF=est:wt08b11.x1 /CLONE=IMAGE:2506845 /UG=Hs.109358 ATPase, Class V, type 10B AW006935 ATPase, class V, type 10B ATP10B 23120 NM_025153 /// XM_005265849 /// XM_006714833 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214071_at AI082827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI082827 /FEA=EST /DB_XREF=gi:3417803 /DB_XREF=est:ox78b09.x1 /CLONE=IMAGE:1662425 /UG=Hs.154145 hypothetical protein FLJ11585 AI082827 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type GNAL 2774 NM_001142339 /// NM_001261443 /// NM_001261444 /// NM_002071 /// NM_182978 /// XM_006722323 /// XM_006722324 /// XR_243798 0001975 // response to amphetamine // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // not recorded /// 0031000 // response to caffeine // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 214072_x_at AA679297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA679297 /FEA=EST /DB_XREF=gi:2659819 /DB_XREF=est:zi28c04.s1 /CLONE=IMAGE:432102 /UG=Hs.109494 secreted protein of unknown function AA679297 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214073_at BG475299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG475299 /FEA=EST /DB_XREF=gi:13407677 /DB_XREF=est:602491364F1 /CLONE=IMAGE:4620519 /UG=Hs.119257 ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) BG475299 cortactin CTTN 2017 NM_001184740 /// NM_005231 /// NM_138565 /// XM_006718447 /// XM_006718448 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214074_s_at BG475299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG475299 /FEA=EST /DB_XREF=gi:13407677 /DB_XREF=est:602491364F1 /CLONE=IMAGE:4620519 /UG=Hs.119257 ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) BG475299 cortactin CTTN 2017 NM_001184740 /// NM_005231 /// NM_138565 /// XM_006718447 /// XM_006718448 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214075_at AI984136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984136 /FEA=EST /DB_XREF=gi:5811355 /DB_XREF=est:wu21b09.x1 /CLONE=IMAGE:2520665 /UG=Hs.109494 secreted protein of unknown function AI984136 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214076_at AI697803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI697803 /FEA=EST /DB_XREF=gi:4985703 /DB_XREF=est:we17e05.x1 /CLONE=IMAGE:2341376 /UG=Hs.114963 Homo Sapiens (clone B3B3E13) chromosome 4p16.3 DNA fragment AI697803 glucose-fructose oxidoreductase domain containing 2 GFOD2 81577 NM_001243650 /// NM_030819 /// NR_027398 /// XM_006721288 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 214077_x_at H15129 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H15129 /FEA=EST /DB_XREF=gi:879949 /DB_XREF=est:ym30b02.s1 /CLONE=IMAGE:49680 /UG=Hs.117313 Meis (mouse) homolog 3 H15129 Meis homeobox 3 pseudogene 1 MEIS3P1 4213 NR_002211 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214078_at AF070581 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070581.1 /DEF=Homo sapiens clone 24540 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387953 /UG=Hs.153529 Homo sapiens clone 24540 mRNA sequence AF070581 Homo sapiens primary neuroblastoma cDNA, clone:Nbla04246, full insert sequence. AF070581 214079_at AK000345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000345.1 /DEF=Homo sapiens cDNA FLJ20338 fis, clone HEP12179. /FEA=mRNA /DB_XREF=gi:7020368 /UG=Hs.152677 Homo sapiens cDNA FLJ20338 fis, clone HEP12179 AK000345 dehydrogenase/reductase (SDR family) member 2 DHRS2 10202 NM_005794 /// NM_182908 /// XM_005267249 /// XM_006720000 /// XM_006720001 /// XM_006720002 /// XR_245654 /// XR_429285 /// XR_429286 0008152 // metabolic process // inferred from electronic annotation /// 0008207 // C21-steroid hormone metabolic process // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0043011 // myeloid dendritic cell differentiation // inferred from expression pattern /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004090 // carbonyl reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 214080_x_at AI815793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI815793 /FEA=EST /DB_XREF=gi:5431339 /DB_XREF=est:au42d05.x1 /CLONE=IMAGE:2517417 /UG=Hs.1432 protein kinase C substrate 80K-H AI815793 protein kinase C substrate 80K-H PRKCSH 5589 NM_001001329 /// NM_001289102 /// NM_001289103 /// NM_001289104 /// NM_002743 /// XM_006722795 /// XM_006722796 /// XM_006722797 /// XM_006722798 /// XR_430144 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006491 // N-glycan processing // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 214081_at AF070526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070526.1 /DEF=Homo sapiens clone 24787 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387881 /UG=Hs.13429 Homo sapiens clone 24787 mRNA sequence AF070526 plexin domain containing 1 PLXDC1 57125 NM_020405 /// XM_006721981 /// XM_006721982 /// XM_006721983 /// XM_006721984 0001525 // angiogenesis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214082_at AW003516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003516 /FEA=EST /DB_XREF=gi:5850421 /DB_XREF=est:wq66h01.x1 /CLONE=IMAGE:2476273 /UG=Hs.13503 inactivation escape 2 AW003516 carbonic anhydrase VB, mitochondrial CA5B 11238 NM_007220 /// XM_005274442 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214083_at AW772123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW772123 /FEA=EST /DB_XREF=gi:7704186 /DB_XREF=est:hn67g05.x1 /CLONE=IMAGE:3032984 /UG=Hs.171734 protein phosphatase 2, regulatory subunit B (B56), gamma isoform AW772123 protein phosphatase 2, regulatory subunit B', gamma PPP2R5C 5527 NM_001161725 /// NM_001161726 /// NM_002719 /// NM_178586 /// NM_178587 /// NM_178588 /// XM_005267819 /// XM_005267820 /// XM_005267822 /// XM_005267823 /// XM_005267824 /// XM_005267826 /// XM_005267827 0006508 // proteolysis // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // non-traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // non-traceable author statement 214084_x_at AW072388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW072388 /FEA=EST /DB_XREF=gi:6027386 /DB_XREF=est:xa07d05.x1 /CLONE=IMAGE:2567625 /UG=Hs.1583 neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) AW072388 neutrophil cytosolic factor 1 NCF1 653361 NM_000265 /// XM_005250543 /// XM_005250544 /// XR_242262 0001878 // response to yeast // inferred from electronic annotation /// 0001909 // leukocyte mediated cytotoxicity // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006612 // protein targeting to membrane // inferred from direct assay /// 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006968 // cellular defense response // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from mutant phenotype /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // traceable author statement /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0070946 // neutrophil mediated killing of gram-positive bacterium // inferred from electronic annotation /// 0070947 // neutrophil mediated killing of fungus // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0032010 // phagolysosome // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008942 // nitrite reductase [NAD(P)H] activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from mutant phenotype /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 214085_x_at AI912583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI912583 /FEA=EST /DB_XREF=gi:5632438 /DB_XREF=est:we11d05.x1 /CLONE=IMAGE:2340777 /UG=Hs.154762 HIV-1 rev binding protein 2 AI912583 GLI pathogenesis-related 1 GLIPR1 11010 NM_006851 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214086_s_at AK001980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001980.1 /DEF=Homo sapiens cDNA FLJ11118 fis, clone PLACE1006011, highly similar to Homo sapiens mRNA for poly(ADP-ribose) polymerase-2. /FEA=mRNA /DB_XREF=gi:7023585 /UG=Hs.24284 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 AK001980 poly (ADP-ribose) polymerase 2 PARP2 10038 NM_001042618 /// NM_005484 /// XM_005267247 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 214087_s_at BF593509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF593509 /FEA=EST /DB_XREF=gi:11685755 /DB_XREF=est:7q03h03.x1 /CLONE=IMAGE:3676660 /UG=Hs.169849 myosin-binding protein C, slow-type BF593509 myosin binding protein C, slow type MYBPC1 4604 NM_001254718 /// NM_001254719 /// NM_001254720 /// NM_001254721 /// NM_001254722 /// NM_001254723 /// NM_002465 /// NM_206819 /// NM_206820 /// NM_206821 /// XM_005268876 /// XM_006719405 /// XM_006719406 /// XM_006719407 /// XM_006719408 /// XM_006719409 /// XM_006719410 /// XM_006719411 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0032982 // myosin filament // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement /// 0031432 // titin binding // inferred from sequence or structural similarity 214088_s_at AW080549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW080549 /FEA=EST /DB_XREF=gi:6035701 /DB_XREF=est:xc33a08.x1 /CLONE=IMAGE:2586038 /UG=Hs.169238 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) AW080549 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) FUT3 2525 NM_000149 /// NM_001097639 /// NM_001097640 /// NM_001097641 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009988 // cell-cell recognition // inferred by curator /// 0036065 // fucosylation // inferred from direct assay /// 0036065 // fucosylation // inferred from electronic annotation /// 0042355 // L-fucose catabolic process // non-traceable author statement /// 0043413 // macromolecule glycosylation // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // inferred from direct assay 214089_at AA976278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA976278 /FEA=EST /DB_XREF=gi:3152070 /DB_XREF=est:oq67c04.s1 /CLONE=IMAGE:1591398 /UG=Hs.227400 mitogen-activated protein kinase kinase kinase kinase 3 AA976278 ribosomal protein S8 RPS8 6202 NM_001012 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 214090_at BF732462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF732462 /FEA=EST /DB_XREF=gi:12057465 /DB_XREF=est:nae10c02.x1 /CLONE=IMAGE:3434859 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator BF732462 PRKC, apoptosis, WT1, regulator PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 214091_s_at AW149846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149846 /FEA=EST /DB_XREF=gi:6197742 /DB_XREF=est:xf42h12.x1 /CLONE=IMAGE:2620775 /UG=Hs.172153 glutathione peroxidase 3 (plasma) AW149846 glutathione peroxidase 3 (plasma) GPX3 2878 NM_002084 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // traceable author statement /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // not recorded /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0008134 // transcription factor binding // traceable author statement /// 0008430 // selenium binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 214092_x_at AI928127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI928127 /FEA=EST /DB_XREF=gi:5664091 /DB_XREF=est:wp11d09.x1 /CLONE=IMAGE:2464529 /UG=Hs.190452 KIAA0365 gene product AI928127 SURP and G patch domain containing 2 SUGP2 10147 NM_001017392 /// NM_014884 /// XR_430120 /// XR_430121 /// XR_430122 /// XR_430123 /// XR_430124 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214093_s_at AA156865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156865 /FEA=EST /DB_XREF=gi:1728480 /DB_XREF=est:zl20f08.s1 /CLONE=IMAGE:502503 /UG=Hs.22370 Homo sapiens mRNA; cDNA DKFZp564O0122 (from clone DKFZp564O0122) AA156865 far upstream element (FUSE) binding protein 1 FUBP1 8880 NM_003902 /// XM_005271309 /// XM_006711021 /// XM_006711022 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214094_at AA156865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156865 /FEA=EST /DB_XREF=gi:1728480 /DB_XREF=est:zl20f08.s1 /CLONE=IMAGE:502503 /UG=Hs.22370 Homo sapiens mRNA; cDNA DKFZp564O0122 (from clone DKFZp564O0122) AA156865 far upstream element (FUSE) binding protein 1 FUBP1 8880 NM_003902 /// XM_005271309 /// XM_006711021 /// XM_006711022 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214095_at AW190316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190316 /FEA=EST /DB_XREF=gi:6464796 /DB_XREF=est:xl13g08.x1 /CLONE=IMAGE:2676158 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma AW190316 serine hydroxymethyltransferase 2 (mitochondrial) SHMT2 6472 NM_001166356 /// NM_001166357 /// NM_001166358 /// NM_001166359 /// NM_005412 /// NR_029415 /// NR_029416 /// NR_029417 /// NR_048562 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019264 // glycine biosynthetic process from serine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004372 // glycine hydroxymethyltransferase activity // inferred from direct assay /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008732 // L-allo-threonine aldolase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 214096_s_at AW190316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190316 /FEA=EST /DB_XREF=gi:6464796 /DB_XREF=est:xl13g08.x1 /CLONE=IMAGE:2676158 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma AW190316 serine hydroxymethyltransferase 2 (mitochondrial) SHMT2 6472 NM_001166356 /// NM_001166357 /// NM_001166358 /// NM_001166359 /// NM_005412 /// NR_029415 /// NR_029416 /// NR_029417 /// NR_048562 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019264 // glycine biosynthetic process from serine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004372 // glycine hydroxymethyltransferase activity // inferred from direct assay /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008732 // L-allo-threonine aldolase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 214097_at AW024383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024383 /FEA=EST /DB_XREF=gi:5877913 /DB_XREF=est:wv03e06.x1 /CLONE=IMAGE:2528482 /UG=Hs.1948 ribosomal protein S21 AW024383 ribosomal protein S21 RPS21 6227 NM_001024 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0000461 // endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0042274 // ribosomal small subunit biogenesis // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 214098_at AB029030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029030.1 /DEF=Homo sapiens mRNA for KIAA1107 protein, partial cds. /FEA=mRNA /GEN=KIAA1107 /PROD=KIAA1107 protein /DB_XREF=gi:5689550 /UG=Hs.21554 KIAA1107 protein AB029030 KIAA1107 KIAA1107 23285 NM_015237 214099_s_at AK001619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001619.1 /DEF=Homo sapiens cDNA FLJ10757 fis, clone NT2RP3004578, highly similar to Homo sapiens mRNA for KIAA0477 protein. /FEA=mRNA /DB_XREF=gi:7022984 /UG=Hs.323580 Homo sapiens cDNA FLJ10757 fis, clone NT2RP3004578, highly similar to Homo sapiens mRNA for KIAA0477 protein AK001619 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 214100_x_at AI284845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI284845 /FEA=EST /DB_XREF=gi:3923078 /DB_XREF=est:qu12a01.x1 /CLONE=IMAGE:1964520 /UG=Hs.272820 hypothetical protein FLJ10267 AI284845 NOP2/Sun domain family, member 5 pseudogene 1 NSUN5P1 155400 NM_001039575 /// NM_001039576 /// NR_033322 /// NR_104013 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 214101_s_at BG153399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG153399 /FEA=EST /DB_XREF=gi:12665429 /DB_XREF=est:nad34c06.x1 /CLONE=IMAGE:3367306 /UG=Hs.293007 aminopeptidase puromycin sensitive BG153399 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 /// XM_006722187 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 214102_at AK023737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023737.1 /DEF=Homo sapiens cDNA FLJ13675 fis, clone PLACE1011875, highly similar to Homo sapiens mRNA for KIAA0580 protein. /FEA=mRNA /DB_XREF=gi:10435758 /UG=Hs.287588 Homo sapiens cDNA FLJ13675 fis, clone PLACE1011875, highly similar to Homo sapiens mRNA for KIAA0580 protein AK023737 214103_s_at BE669921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE669921 /FEA=EST /DB_XREF=gi:10030462 /DB_XREF=est:7e27c04.x1 /CLONE=IMAGE:3283686 /UG=Hs.301746 RAP2A, member of RAS oncogene family BE669921 RAP2A, member of RAS oncogene family RAP2A 5911 NM_021033 0006184 // GTP catabolic process // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay 0005829 // cytosol // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 214104_at AI703188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI703188 /FEA=EST /DB_XREF=gi:4991088 /DB_XREF=est:wd92g12.x1 /CLONE=IMAGE:2339110 /UG=Hs.301642 G-protein coupled receptor AI703188 G protein-coupled receptor 161 GPR161 23432 NM_001267609 /// NM_001267610 /// NM_001267611 /// NM_001267612 /// NM_001267613 /// NM_001267614 /// NM_007369 /// NM_153832 /// XM_005245055 /// XM_005245056 /// XM_005245057 /// XM_006711251 /// XM_006711252 /// XM_006711253 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 1901621 // negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity 214105_at AI922872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922872 /FEA=EST /DB_XREF=gi:5658836 /DB_XREF=est:wn64f03.x1 /CLONE=IMAGE:2450237 /UG=Hs.296176 STAT induced STAT inhibitor 3 AI922872 suppressor of cytokine signaling 3 SOCS3 9021 NM_003955 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060708 // spongiotrophoblast differentiation // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214106_s_at AI762113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762113 /FEA=EST /DB_XREF=gi:5177780 /DB_XREF=est:wi53h03.x1 /CLONE=IMAGE:2394005 /UG=Hs.6487 Xq28, 2000bp sequence contg. ORF AI762113 GDP-mannose 4,6-dehydratase GMDS 2762 NM_001253846 /// NM_001500 /// XM_006715066 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0019673 // GDP-mannose metabolic process // inferred from direct assay /// 0019673 // GDP-mannose metabolic process // inferred from genetic interaction /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from direct assay /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008446 // GDP-mannose 4,6-dehydratase activity // inferred from direct assay /// 0008446 // GDP-mannose 4,6-dehydratase activity // inferred from genetic interaction /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0070401 // NADP+ binding // inferred from direct assay 214107_x_at AW340850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW340850 /FEA=EST /DB_XREF=gi:6837476 /DB_XREF=est:xr31f01.x1 /CLONE=IMAGE:2761753 /UG=Hs.326350 Homo sapiens cDNA FLJ11822 fis, clone HEMBA1006485, highly similar to PUROMYCIN-SENSITIVE AMINOPEPTIDASE (EC 3.4.11.-) AW340850 aminopeptidase puromycin sensitive pseudogene LOC440434 440434 NR_036750 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214108_at AI346181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346181 /FEA=EST /DB_XREF=gi:4083387 /DB_XREF=est:qp49b03.x1 /CLONE=IMAGE:1926317 /UG=Hs.42712 MAX protein AI346181 MYC associated factor X MAX 4149 NM_001271068 /// NM_001271069 /// NM_002382 /// NM_145112 /// NM_145113 /// NM_145114 /// NM_145116 /// NM_197957 /// NR_073137 /// NR_073138 /// XR_429315 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 214109_at AI659561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI659561 /FEA=EST /DB_XREF=gi:4763131 /DB_XREF=est:tu12d08.x1 /CLONE=IMAGE:2250831 /UG=Hs.62354 cell division cycle 4-like AI659561 LPS-responsive vesicle trafficking, beach and anchor containing LRBA 987 NM_001199282 /// NM_006726 /// XM_005263372 /// XM_005263373 /// XM_005263374 /// XM_005263375 /// XM_005263376 /// XM_005263377 /// XM_006714429 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214110_s_at BF195104 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195104 /FEA=EST /DB_XREF=gi:11081627 /DB_XREF=est:7n15a07.x1 /CLONE=IMAGE:3564565 /UG=Hs.56729 lymphocyte-specific protein 1 BF195104 lymphocyte-specific protein 1 pseudogene /// lymphocyte-specific protein 1 pseudogene LOC645166 /// LOC654342 645166 /// 654342 NR_027238 /// NR_027354 /// NR_027355 /// NR_027356 214111_at AF070577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070577.1 /DEF=Homo sapiens clone 24461 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387949 /UG=Hs.4817 Homo sapiens clone 24461 mRNA sequence AF070577 opioid binding protein/cell adhesion molecule-like OPCML 4978 NM_001012393 /// NM_002545 /// XM_005271574 /// XM_005271575 /// XM_005271578 /// XM_005271579 /// XM_006718846 0007155 // cell adhesion // inferred from electronic annotation /// 0008038 // neuron recognition // traceable author statement /// 0038003 // opioid receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004985 // opioid receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214112_s_at AA543076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA543076 /FEA=EST /DB_XREF=gi:2291556 /DB_XREF=est:nf96f02.s1 /CLONE=IMAGE:927771 /UG=Hs.82171 Homo sapiens (clone 115392) mRNA AA543076 chromosome X open reading frame 40A /// chromosome X open reading frame 40B CXorf40A /// CXorf40B 91966 /// 541578 NM_001013845 /// NM_001171907 /// NM_001171908 /// NM_001171909 /// NM_178124 /// XM_005262348 /// XM_005262349 /// XM_005262350 /// XM_005274698 /// XM_005274699 /// XM_005274700 /// XM_005274701 /// XM_005274702 /// XM_005278212 /// XM_006724825 /// XM_006724826 /// XM_006724827 0005515 // protein binding // inferred from physical interaction 214113_s_at AI738479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738479 /FEA=EST /DB_XREF=gi:5100460 /DB_XREF=est:wi32d06.x1 /CLONE=IMAGE:2391947 /UG=Hs.65648 RNA binding motif protein 8A AI738479 RNA binding motif protein 8A RBM8A 9939 NM_005105 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214114_x_at AK023141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023141.1 /DEF=Homo sapiens cDNA FLJ13079 fis, clone NT2RP3002004, moderately similar to H.sapiens mRNA for FAST kinase. /FEA=mRNA /DB_XREF=gi:10434926 /UG=Hs.75087 Fas-activated serinethreonine kinase AK023141 Fas-activated serine/threonine kinase FASTK 10922 NM_001258461 /// NM_006712 /// NM_033015 /// XM_005249932 /// XM_005249933 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033867 // Fas-activated serine/threonine kinase activity // inferred from electronic annotation 214115_at AI814466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI814466 /FEA=EST /DB_XREF=gi:5425681 /DB_XREF=est:wj73e07.x1 /CLONE=IMAGE:2408484 /UG=Hs.74669 vesicle-associated membrane protein 5 (myobrevin) AI814466 vesicle-associated membrane protein 5 VAMP5 10791 NM_006634 0006887 // exocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation 0005770 // late endosome // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // not recorded /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031201 // SNARE complex // not recorded /// 0031301 // integral component of organelle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded 214116_at AI767414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767414 /FEA=EST /DB_XREF=gi:5233843 /DB_XREF=est:wi95g11.x1 /CLONE=IMAGE:2401124 /UG=Hs.78885 biotinidase AI767414 biotinidase BTD 686 NM_000060 /// NM_001281723 /// NM_001281724 /// NM_001281725 /// NM_001281726 /// XM_005265417 /// XM_006713314 /// XM_006713315 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004075 // biotin carboxylase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0047708 // biotinidase activity // inferred from electronic annotation 214117_s_at AI767414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767414 /FEA=EST /DB_XREF=gi:5233843 /DB_XREF=est:wi95g11.x1 /CLONE=IMAGE:2401124 /UG=Hs.78885 biotinidase AI767414 biotinidase BTD 686 NM_000060 /// NM_001281723 /// NM_001281724 /// NM_001281725 /// NM_001281726 /// XM_005265417 /// XM_006713314 /// XM_006713315 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004075 // biotin carboxylase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0047708 // biotinidase activity // inferred from electronic annotation 214118_x_at AI205598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI205598 /FEA=EST /DB_XREF=gi:3764270 /DB_XREF=est:qg30f05.x1 /CLONE=IMAGE:1836705 /UG=Hs.75737 pericentriolar material 1 AI205598 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 214119_s_at AI936769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI936769 /FEA=EST /DB_XREF=gi:5675639 /DB_XREF=est:wp69c11.x1 /CLONE=IMAGE:2467028 /UG=Hs.752 FK506-binding protein 1A (12kD) AI936769 FK506 binding protein 1A, 12kDa /// uncharacterized LOC101929368 FKBP1A /// LOC101929368 2280 /// 101929368 NM_000801 /// NM_001199786 /// NM_054014 /// XR_245428 /// XR_247917 /// XR_253167 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0018208 // peptidyl-proline modification // /// 0022417 // protein maturation by protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from genetic interaction /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded /// 0070588 // calcium ion transmembrane transport // non-traceable author statement /// 1902991 // regulation of amyloid precursor protein catabolic process // inferred from genetic interaction /// 1990000 // amyloid fibril formation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030424 // axon // /// 0033017 // sarcoplasmic reticulum membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005527 // macrolide binding // non-traceable author statement /// 0005528 // FK506 binding // inferred from direct assay /// 0005528 // FK506 binding // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 214120_at AW157535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157535 /FEA=EST /DB_XREF=gi:6228936 /DB_XREF=est:au83d11.x1 /CLONE=IMAGE:2782869 /UG=Hs.102576 ret finger protein-like 1 antisense AW157535 RFPL1 antisense RNA 1 RFPL1S 10740 NR_002727 214121_x_at AA086229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA086229 /FEA=EST /DB_XREF=gi:1628852 /DB_XREF=est:zn60b06.s1 /CLONE=IMAGE:562547 /UG=Hs.102948 enigma (LIM domain protein) AA086229 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214122_at AA086229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA086229 /FEA=EST /DB_XREF=gi:1628852 /DB_XREF=est:zn60b06.s1 /CLONE=IMAGE:562547 /UG=Hs.102948 enigma (LIM domain protein) AA086229 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 214123_s_at AI126492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI126492 /FEA=EST /DB_XREF=gi:3595006 /DB_XREF=est:qd82h06.x1 /CLONE=IMAGE:1736027 /UG=Hs.104258 Homo sapiens mRNA, exon 1, 2, 3, 4, clone:RES4-24A AI126492 NOP14 antisense RNA 1 NOP14-AS1 317648 NR_015453 214124_x_at AL043487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL043487 /FEA=EST /DB_XREF=gi:5422874 /DB_XREF=est:DKFZp434B2027_s1 /CLONE=DKFZp434B2027 /UG=Hs.108548 PABP-interacting protein 2 AL043487 FGFR1 oncogene partner FGFR1OP 11116 NM_001278690 /// NM_007045 /// NM_194429 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay 214125_s_at BF440021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF440021 /FEA=EST /DB_XREF=gi:11452538 /DB_XREF=est:nac52c04.x1 /CLONE=IMAGE:3406063 /UG=Hs.109494 secreted protein of unknown function BF440021 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214126_at N39314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N39314 /FEA=EST /DB_XREF=gi:1162521 /DB_XREF=est:yv25c06.s1 /CLONE=IMAGE:243754 /UG=Hs.11173 potassium inwardly-rectifying channel, subfamily J, member 6 N39314 214127_s_at H28020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H28020 /FEA=EST /DB_XREF=gi:898373 /DB_XREF=est:yl63g07.s1 /CLONE=IMAGE:162972 /UG=Hs.111801 arsenate resistance protein ARS2 H28020 serrate, RNA effector molecule SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214128_at AB014559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014559.1 /DEF=Homo sapiens mRNA for KIAA0659 protein, partial cds. /FEA=mRNA /GEN=KIAA0659 /PROD=KIAA0659 protein /DB_XREF=gi:3327131 /UG=Hs.124275 chromosome 11open reading frame 11 AB014559 diacylglycerol lipase, alpha DAGLA 747 NM_006133 /// XM_005274230 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // inferred from direct assay /// 0046340 // diacylglycerol catabolic process // inferred from direct assay /// 0071926 // endocannabinoid signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214129_at AI821791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI821791 /FEA=EST /DB_XREF=gi:5440870 /DB_XREF=est:np33h04.x5 /CLONE=IMAGE:1118167 /UG=Hs.129928 KIAA0477 gene product AI821791 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 214130_s_at AI821791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI821791 /FEA=EST /DB_XREF=gi:5440870 /DB_XREF=est:np33h04.x5 /CLONE=IMAGE:1118167 /UG=Hs.129928 KIAA0477 gene product AI821791 phosphodiesterase 4D interacting protein-like /// uncharacterized LOC100996761 /// uncharacterized LOC101929792 /// myomegalin-like /// phosphodiesterase 4D interacting protein LOC100996724 /// LOC100996761 /// LOC101929792 /// LOC101930416 /// PDE4DIP 9659 /// 100996724 /// 100996761 /// 101929792 /// 101930416 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_003846757 /// XM_003846758 /// XM_005272981 /// XM_005275858 /// XM_005276096 /// XM_005276138 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_005277502 /// XM_006710077 /// XM_006710078 /// XM_006710079 /// XM_006710080 /// XM_006710081 /// XM_006711101 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 /// XM_006711706 /// XM_006726347 /// XM_006726359 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 214131_at AL049280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049280.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K143 (from clone DKFZp564K143). /FEA=mRNA /DB_XREF=gi:4500037 /UG=Hs.155397 Homo sapiens mRNA; cDNA DKFZp564K143 (from clone DKFZp564K143) AL049280 taxilin gamma pseudogene, Y-linked TXLNGY 246126 NM_001005852 /// NR_045128 /// NR_045129 0019905 // syntaxin binding // inferred from electronic annotation 214132_at BG232034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG232034 /FEA=EST /DB_XREF=gi:12727189 /DB_XREF=est:naf35f07.x1 /CLONE=IMAGE:4143109 /UG=Hs.155433 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 BG232034 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 ATP5C1 509 NM_001001973 /// NM_005174 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred by curator /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 214133_at AI611214 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI611214 /FEA=EST /DB_XREF=gi:4620381 /DB_XREF=est:tw41g05.x1 /CLONE=IMAGE:2262296 /UG=Hs.159593 mucin 6, gastric AI611214 mucin 6, oligomeric mucus/gel-forming MUC6 4588 NM_005961 /// XM_006725532 /// XM_006725760 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // non-traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement 0005201 // extracellular matrix structural constituent // non-traceable author statement 214134_at BF939689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939689 /FEA=EST /DB_XREF=gi:12357100 /DB_XREF=est:nac80b04.x1 /CLONE=IMAGE:3440575 /UG=Hs.159629 myosin IXB BF939689 KIAA1211-like KIAA1211L 343990 NM_207362 /// XM_005263923 /// XM_005263924 /// XM_005263925 /// XM_005263926 /// XM_005263927 214135_at BE551219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551219 /FEA=EST /DB_XREF=gi:9792911 /DB_XREF=est:7b56b11.x1 /CLONE=IMAGE:3232221 /UG=Hs.16762 Homo sapiens mRNA; cDNA DKFZp564B2062 (from clone DKFZp564B2062) BE551219 claudin 18 CLDN18 51208 NM_001002026 /// NM_016369 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 214136_at W80642 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W80642 /FEA=EST /DB_XREF=gi:1391659 /DB_XREF=est:zh50h11.s1 /CLONE=IMAGE:415557 /UG=Hs.16951 DKFZP586P2219 protein W80642 nudix (nucleoside diphosphate linked moiety X)-type motif 13 NUDT13 25961 NM_001283014 /// NM_001283015 /// NM_001283016 /// NM_001283017 /// NM_001283019 /// NM_015901 /// NR_104264 /// XM_005269684 /// XM_006717749 /// XM_006717750 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214137_at AI806482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806482 /FEA=EST /DB_XREF=gi:5393048 /DB_XREF=est:wf08e12.x1 /CLONE=IMAGE:2350030 /UG=Hs.171992 protein tyrosine phosphatase, receptor type, J AI806482 protein tyrosine phosphatase, receptor type, J PTPRJ 5795 NM_001098503 /// NM_002843 /// XM_006718269 0001570 // vasculogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010572 // positive regulation of platelet activation // inferred from electronic annotation /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043116 // negative regulation of vascular permeability // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060242 // contact inhibition // non-traceable author statement /// 2000272 // negative regulation of receptor activity // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from direct assay /// 0016791 // phosphatase activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction /// 0070097 // delta-catenin binding // inferred from physical interaction 214138_at AA284829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284829 /FEA=EST /DB_XREF=gi:1927397 /DB_XREF=est:zt22c06.s1 /CLONE=IMAGE:713866 /UG=Hs.17364 ESTs, Weakly similar to Z139_HUMAN ZINC FINGER PROTEIN 13 H.sapiens AA284829 zinc finger protein 79 ZNF79 7633 NM_001286696 /// NM_001286697 /// NM_001286698 /// NM_007135 /// XM_006717279 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214139_at AI051476 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI051476 /FEA=EST /DB_XREF=gi:3307010 /DB_XREF=est:ow29e10.s1 /CLONE=IMAGE:1648266 /UG=Hs.17428 RBP1-like protein AI051476 AT rich interactive domain 4B (RBP1-like) ARID4B 51742 NM_001206794 /// NM_016374 /// NM_031371 /// XM_005273160 /// XM_006711781 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation /// 0036124 // histone H3-K9 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214140_at AI827990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI827990 /FEA=EST /DB_XREF=gi:5448582 /DB_XREF=est:wf12c10.x1 /CLONE=IMAGE:2350386 /UG=Hs.180408 solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 AI827990 solute carrier family 25 (mitochondrial carrier), member 16 SLC25A16 8034 NM_152707 /// XM_005270183 /// XM_006717987 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // non-traceable author statement /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // non-traceable author statement 214141_x_at BF033354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF033354 /FEA=EST /DB_XREF=gi:10741066 /DB_XREF=est:601458055F1 /CLONE=IMAGE:3861709 /UG=Hs.184167 splicing factor, arginineserine-rich 7 (35kD) BF033354 serine/arginine-rich splicing factor 7 SRSF7 6432 NM_001031684 /// NM_001195446 /// NM_006276 /// XM_005264484 /// XM_005264485 /// XM_005264486 /// XR_426994 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214142_at AI732905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732905 /FEA=EST /DB_XREF=gi:5054018 /DB_XREF=est:of72a12.x5 /CLONE=IMAGE:1435870 /UG=Hs.184507 Homo sapiens Chromosome 16 BAC clone CIT987SK-A-328A3 AI732905 zymogen granule protein 16 ZG16 653808 NM_152338 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0060205 // cytoplasmic membrane-bounded vesicle lumen // inferred from electronic annotation 214143_x_at AI560573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI560573 /FEA=EST /DB_XREF=gi:4510914 /DB_XREF=est:tq49c03.x1 /CLONE=IMAGE:2212132 /UG=Hs.184582 ribosomal protein L24 AI560573 ribosomal protein L24 RPL24 6152 NM_000986 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0015808 // L-alanine transport // inferred from electronic annotation /// 0015816 // glycine transport // inferred from electronic annotation /// 0015824 // proline transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0035524 // proline transmembrane transport // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005280 // hydrogen:amino acid symporter activity // inferred from electronic annotation /// 0015180 // L-alanine transmembrane transporter activity // inferred from electronic annotation /// 0015187 // glycine transmembrane transporter activity // inferred from electronic annotation /// 0015187 // glycine transmembrane transporter activity // inferred from mutant phenotype /// 0015193 // L-proline transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214144_at BF432147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432147 /FEA=EST /DB_XREF=gi:11444261 /DB_XREF=est:nab80a07.x1 /CLONE=IMAGE:3273900 /UG=Hs.194638 polymerase (RNA) II (DNA directed) polypeptide D BF432147 polymerase (RNA) II (DNA directed) polypeptide D POLR2D 5433 NM_004805 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // not recorded /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0031990 // mRNA export from nucleus in response to heat stress // not recorded /// 0034402 // recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex // not recorded /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // not recorded /// 0050434 // positive regulation of viral transcription // traceable author statement 0000932 // cytoplasmic mRNA processing body // not recorded /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // not recorded /// 0003727 // single-stranded RNA binding // not recorded /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // not recorded 214145_s_at BG223341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG223341 /FEA=EST /DB_XREF=gi:12708862 /DB_XREF=est:naf79f03.x1 /CLONE=IMAGE:4170365 /UG=Hs.198037 KIAA0599 protein BG223341 spectrin, beta, erythrocytic SPTB 6710 NM_000347 /// NM_001024858 /// XM_005268023 /// XM_006720241 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014731 // spectrin-associated cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 214146_s_at R64130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R64130 /FEA=EST /DB_XREF=gi:836009 /DB_XREF=est:yi18h03.s1 /CLONE=IMAGE:139637 /UG=Hs.2164 pro-platelet basic protein (includes platelet basic protein, beta-thromboglobulin, connective tissue-activating peptide III, neutrophil-activating peptide-2) R64130 pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) PPBP 5473 NM_002704 0002576 // platelet degranulation // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 214147_at AL046350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046350 /FEA=EST /DB_XREF=gi:5434427 /DB_XREF=est:DKFZp434J097_s1 /CLONE=DKFZp434J097 /UG=Hs.225433 Homo sapiens mRNA; cDNA DKFZp434G153 (from clone DKFZp434G153) AL046350 maestro heat-like repeat family member 7 MROH7 374977 NM_001039464 /// NM_001291332 /// NM_198547 /// NR_026782 /// NR_111931 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 214148_at U90917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U90917.1 /DEF=Human clone 23641 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1913898 /UG=Hs.239 forkhead box M1 U90917 integrin alpha FG-GAP repeat containing 2 /// uncharacterized LOC100507424 ITFG2 /// LOC100507424 55846 /// 100507424 NM_018463 /// NR_038933 /// XM_005253707 /// XM_005253708 /// XM_005253709 /// XR_429017 214149_s_at AI252582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI252582 /FEA=EST /DB_XREF=gi:3849111 /DB_XREF=est:qv25b02.x1 /CLONE=IMAGE:1982571 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD AI252582 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 214150_x_at BE043477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE043477 /FEA=EST /DB_XREF=gi:8360530 /DB_XREF=est:hk39a01.y1 /CLONE=IMAGE:2999016 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD BE043477 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 214151_s_at AU144243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144243 /FEA=EST /DB_XREF=gi:11005764 /DB_XREF=est:AU144243 /CLONE=HEMBA1001328 /UG=Hs.247118 phosphatidylinositol glycan, class B AU144243 cell cycle progression 1 /// DYX1C1-CCPG1 readthrough (NMD candidate) CCPG1 /// DYX1C1-CCPG1 9236 /// 100533483 NM_001204450 /// NM_001204451 /// NM_004748 /// NM_020739 /// NR_037923 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001106 // regulation of Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214152_at AU144243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144243 /FEA=EST /DB_XREF=gi:11005764 /DB_XREF=est:AU144243 /CLONE=HEMBA1001328 /UG=Hs.247118 phosphatidylinositol glycan, class B AU144243 cell cycle progression 1 /// DYX1C1-CCPG1 readthrough (NMD candidate) CCPG1 /// DYX1C1-CCPG1 9236 /// 100533483 NM_001204450 /// NM_001204451 /// NM_004748 /// NM_020739 /// NR_037923 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001106 // regulation of Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214153_at BE467941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE467941 /FEA=EST /DB_XREF=gi:9513716 /DB_XREF=est:hz76b04.x1 /CLONE=IMAGE:3213871 /UG=Hs.250175 homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 BE467941 ELOVL fatty acid elongase 5 ELOVL5 60481 NM_001242828 /// NM_001242830 /// NM_001242831 /// NM_021814 /// XM_005249266 /// XM_005249267 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034625 // fatty acid elongation, monounsaturated fatty acid // inferred from direct assay /// 0034626 // fatty acid elongation, polyunsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 214154_s_at AA888057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA888057 /FEA=EST /DB_XREF=gi:3003732 /DB_XREF=est:nr04c02.s1 /CLONE=IMAGE:1160834 /UG=Hs.25051 plakophilin 2 AA888057 plakophilin 2 PKP2 5318 NM_001005242 /// NM_004572 0002159 // desmosome assembly // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010765 // positive regulation of sodium ion transport // inferred from sequence or structural similarity /// 0016264 // gap junction assembly // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0034334 // adherens junction maintenance // inferred from sequence or structural similarity /// 0045110 // intermediate filament bundle assembly // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086019 // cell-cell signaling involved in cardiac conduction // inferred from mutant phenotype /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 2000810 // regulation of tight junction assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from direct assay /// 0030057 // desmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // non-traceable author statement 0005080 // protein kinase C binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0019215 // intermediate filament binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from sequence or structural similarity 214155_s_at AI743740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI743740 /FEA=EST /DB_XREF=gi:5112028 /DB_XREF=est:wg53d01.x1 /CLONE=IMAGE:2368801 /UG=Hs.26613 Homo sapiens mRNA; cDNA DKFZp586F1323 (from clone DKFZp586F1323) AI743740 La ribonucleoprotein domain family, member 4 LARP4 113251 NM_001170803 /// NM_001170804 /// NM_001170808 /// NM_052879 /// NM_199188 /// NM_199190 /// NR_033200 /// XM_005268613 /// XM_006719215 /// XM_006719216 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0016020 // membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214156_at AL050090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050090.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1018 (from clone DKFZp586F1018). /FEA=mRNA /GEN=DKFZp586F1018 /PROD=hypothetical protein /DB_XREF=gi:4884109 /UG=Hs.26970 DKFZP586F1018 protein AL050090 myosin VIIA and Rab interacting protein MYRIP 25924 NM_001284423 /// NM_001284424 /// NM_001284425 /// NM_001284426 /// NM_015460 /// NR_104316 /// XM_006713099 0006886 // intracellular protein transport // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity 0000145 // exocyst // inferred from electronic annotation /// 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031045 // dense core granule // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 214157_at AA401492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA401492 /FEA=EST /DB_XREF=gi:2053970 /DB_XREF=est:zu69h03.s1 /CLONE=IMAGE:743285 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 AA401492 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 214158_s_at AV682503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV682503 /FEA=EST /DB_XREF=gi:10284366 /DB_XREF=est:AV682503 /CLONE=GKBAME02 /UG=Hs.275086 PR domain containing 10 AV682503 PR domain containing 10 PRDM10 56980 NM_020228 /// NM_199437 /// NM_199438 /// NM_199439 /// XM_006718886 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214159_at AW771015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW771015 /FEA=EST /DB_XREF=gi:7703066 /DB_XREF=est:hn50d05.x1 /CLONE=IMAGE:3027081 /UG=Hs.279020 Homo sapiens mRNA; cDNA DKFZp566E0224 (from clone DKFZp566E0224) AW771015 phospholipase C, epsilon 1 PLCE1 51196 NM_001165979 /// NM_001288989 /// NM_016341 /// XM_006717885 /// XM_006717886 /// XM_006717887 /// XM_006717888 /// XM_006717889 /// XM_006717890 0000187 // activation of MAPK activity // inferred from direct assay /// 0001558 // regulation of cell growth // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred by curator /// 0006651 // diacylglycerol biosynthetic process // traceable author statement /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007507 // heart development // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // non-traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0032835 // glomerulus development // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046578 // regulation of Ras protein signal transduction // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004629 // phospholipase C activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 214160_at AI738463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738463 /FEA=EST /DB_XREF=gi:5100444 /DB_XREF=est:wi32b08.x1 /CLONE=IMAGE:2391927 /UG=Hs.38481 cyclin-dependent kinase 6 AI738463 214161_at BF057458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057458 /FEA=EST /DB_XREF=gi:10811354 /DB_XREF=est:7k44c06.x1 /CLONE=IMAGE:3478259 /UG=Hs.40539 chromosome 8 open reading frame 1 BF057458 oxidative stress induced growth inhibitor family member 2 OSGIN2 734 NM_001126111 /// NM_004337 0007126 // meiotic nuclear division // inferred from electronic annotation 214162_at AF070541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070541.1 /DEF=Homo sapiens clones 24714 and 24715 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387900 /UG=Hs.4267 Homo sapiens clones 24714 and 24715 mRNA sequence AF070541 additional sex combs like transcriptional regulator 3 ASXL3 80816 NM_030632 /// XM_005258356 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214163_at AV700696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700696 /FEA=EST /DB_XREF=gi:10302667 /DB_XREF=est:AV700696 /CLONE=GKCAHB05 /UG=Hs.46967 HSPCO34 protein AV700696 heat shock protein family B (small), member 11 HSPB11 51668 NM_016126 /// XM_005270942 /// XM_005270943 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005929 // cilium // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 214164_x_at BF752277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF752277 /FEA=EST /DB_XREF=gi:12078953 /DB_XREF=est:RC3-BN0428-201100-011-c11 /UG=Hs.5344 adaptor-related protein complex 1, gamma 1 subunit BF752277 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032438 // melanosome organization // inferred by curator /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214165_s_at BF512553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF512553 /FEA=EST /DB_XREF=gi:11597732 /DB_XREF=est:UI-H-BW1-amf-d-06-0-UI.s1 /CLONE=IMAGE:3069731 /UG=Hs.6363 heparan sulfate 6-O-sulfotransferase BF512553 heparan sulfate 6-O-sulfotransferase 1 HS6ST1 9394 NM_004807 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0015015 // heparan sulfate proteoglycan biosynthetic process, enzymatic modification // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048666 // neuron development // inferred from mutant phenotype /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement 0008146 // sulfotransferase activity // inferred from electronic annotation 214166_at AW294107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW294107 /FEA=EST /DB_XREF=gi:6700743 /DB_XREF=est:UI-H-BI2-ahg-c-08-0-UI.s1 /CLONE=IMAGE:2726774 /UG=Hs.64 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) AW294107 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) SDHB 6390 NM_003000 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from sequence or structural similarity /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity 214167_s_at AA555113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA555113 /FEA=EST /DB_XREF=gi:2325652 /DB_XREF=est:nj40g05.s1 /CLONE=IMAGE:995000 /UG=Hs.73742 ribosomal protein, large, P0 AA555113 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214168_s_at AA813018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA813018 /FEA=EST /DB_XREF=gi:2883082 /DB_XREF=est:aj44b11.s1 /CLONE=1393149 /UG=Hs.74614 tight junction protein 1 (zona occludens 1) AA813018 tight junction protein 1 TJP1 7082 NM_003257 /// NM_175610 /// XM_005254616 /// XM_005254617 /// XM_005254618 /// XM_005254619 /// XM_005254620 /// XM_005254621 /// XM_006720660 /// XM_006720661 /// XM_006725553 /// XM_006725554 /// XM_006725555 /// XM_006725556 /// XM_006725557 /// XM_006725558 /// XM_006725559 /// XM_006725560 0001825 // blastocyst formation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0071000 // response to magnetism // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1901350 // cell-cell signaling involved in cell-cell junction organization // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043296 // apical junction complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0046581 // intercellular canaliculus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 214169_at BE615699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE615699 /FEA=EST /DB_XREF=gi:9897298 /DB_XREF=est:601279805F1 /CLONE=IMAGE:3621960 /UG=Hs.7531 KIAA0810 protein BE615699 Sad1 and UNC84 domain containing 1 SUN1 23353 NM_001130965 /// NM_001171944 /// NM_001171945 /// NM_001171946 /// NM_025154 0006810 // transport // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from genetic interaction /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from mutant phenotype /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation 214170_x_at AA669797 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA669797 /FEA=EST /DB_XREF=gi:2631296 /DB_XREF=est:ag36c01.s1 /CLONE=IMAGE:1118880 /UG=Hs.75653 fumarate hydratase AA669797 fumarate hydratase FH 2271 NM_000143 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006106 // fumarate metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0045239 // tricarboxylic acid cycle enzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004333 // fumarate hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 214171_s_at AI810156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI810156 /FEA=EST /DB_XREF=gi:5396722 /DB_XREF=est:wf80b08.x1 /CLONE=IMAGE:2361879 /UG=Hs.7655 U2 small nuclear ribonucleoprotein auxiliary factor (65kD) AI810156 U2 small nuclear RNA auxiliary factor 2 U2AF2 11338 NM_001012478 /// NM_007279 /// XM_006722994 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from electronic annotation 214172_x_at BG032035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG032035 /FEA=EST /DB_XREF=gi:12422926 /DB_XREF=est:602300542F1 /CLONE=IMAGE:4402114 /UG=Hs.79350 RYK receptor-like tyrosine kinase BG032035 receptor-like tyrosine kinase RYK 6259 NM_001005861 /// NM_002958 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from electronic annotation /// 0042813 // Wnt-activated receptor activity // inferred from electronic annotation 214173_x_at AW514900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514900 /FEA=EST /DB_XREF=gi:7152982 /DB_XREF=est:xu89a06.x1 /CLONE=IMAGE:2808850 /UG=Hs.7943 RPB5-mediating protein AW514900 URI1, prefoldin-like chaperone URI1 8725 NM_001252641 /// NM_003796 /// NM_134447 /// NR_045557 /// XM_005259362 /// XM_005259363 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001558 // regulation of cell growth // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0009615 // response to virus // inferred from mutant phenotype /// 0010923 // negative regulation of phosphatase activity // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016272 // prefoldin complex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 214174_s_at BE043700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE043700 /FEA=EST /DB_XREF=gi:8360753 /DB_XREF=est:hk42a07.y1 /CLONE=IMAGE:2999316 /UG=Hs.79691 LIM domain protein BE043700 PDZ and LIM domain 4 PDLIM4 8572 NM_001131027 /// NM_003687 /// XM_006714723 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 214175_x_at AI254547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI254547 /FEA=EST /DB_XREF=gi:3862072 /DB_XREF=est:qv48h06.x1 /CLONE=IMAGE:1984859 /UG=Hs.79691 LIM domain protein AI254547 PDZ and LIM domain 4 PDLIM4 8572 NM_001131027 /// NM_003687 /// XM_006714723 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214176_s_at AI348545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348545 /FEA=EST /DB_XREF=gi:4085751 /DB_XREF=est:qo34h12.x1 /CLONE=IMAGE:1910471 /UG=Hs.8068 hematopoietic PBX-interacting protein AI348545 214177_s_at AI935162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI935162 /FEA=EST /DB_XREF=gi:5674032 /DB_XREF=est:wp14e01.x1 /CLONE=IMAGE:2464824 /UG=Hs.8068 hematopoietic PBX-interacting protein AI935162 pre-B-cell leukemia homeobox interacting protein 1 PBXIP1 57326 NM_020524 0007275 // multicellular organismal development // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003714 // transcription corepressor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214178_s_at AI356682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI356682 /FEA=EST /DB_XREF=gi:4108303 /DB_XREF=est:qy22a10.x1 /CLONE=IMAGE:2012730 /UG=Hs.816 SRY (sex determining region Y)-box 2 AI356682 SRY (sex determining region Y)-box 2 SOX2 6657 NM_003106 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001654 // eye development // inferred from expression pattern /// 0001714 // endodermal cell fate specification // inferred from direct assay /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0009611 // response to wounding // inferred from expression pattern /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0021781 // glial cell fate commitment // non-traceable author statement /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from expression pattern /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from expression pattern /// 0030910 // olfactory placode formation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046148 // pigment biosynthetic process // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048839 // inner ear development // inferred from expression pattern /// 0048852 // diencephalon morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0050973 // detection of mechanical stimulus involved in equilibrioception // inferred from electronic annotation /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 214179_s_at H93013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H93013 /FEA=EST /DB_XREF=gi:1099341 /DB_XREF=est:yv07g07.s1 /CLONE=IMAGE:242076 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 H93013 nuclear factor, erythroid 2-like 1 NFE2L1 4779 NM_003204 /// XM_005257410 /// XM_005257411 /// XM_005257412 /// XM_005257413 /// XM_005257415 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214180_at AW340588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW340588 /FEA=EST /DB_XREF=gi:6837214 /DB_XREF=est:hd05a05.x1 /CLONE=IMAGE:2908592 /UG=Hs.8736 Homo sapiens mRNA; cDNA DKFZp564H203 (from clone DKFZp564H203) AW340588 mannosidase, alpha, class 1C, member 1 MAN1C1 57134 NM_001289010 /// NM_020379 /// XM_005245945 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // traceable author statement 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 214181_x_at AI735692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI735692 /FEA=EST /DB_XREF=gi:5057216 /DB_XREF=est:at20b12.x1 /CLONE=IMAGE:2355647 /UG=Hs.88411 lymphocyte antigen 117 AI735692 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 214182_at AA243143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA243143 /FEA=EST /DB_XREF=gi:1874138 /DB_XREF=est:zs13h04.s1 /CLONE=IMAGE:685111 /UG=Hs.89474 ADP-ribosylation factor 6 AA243143 214183_s_at X91817 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X91817.1 /DEF=H.sapiens mRNA for transketolase-like protein (2418 bp). /FEA=mRNA /PROD=transketolase /DB_XREF=gi:1232174 /UG=Hs.102866 transketolase-like 1 X91817 transketolase-like 1 TKTL1 8277 NM_001145933 /// NM_001145934 /// NM_012253 0006007 // glucose catabolic process // traceable author statement /// 0006772 // thiamine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004802 // transketolase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214184_at AW195837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW195837 /FEA=EST /DB_XREF=gi:6475067 /DB_XREF=est:xn41f12.x1 /CLONE=IMAGE:2696303 /UG=Hs.104555 neuropeptide FF-amide peptide precursor AW195837 neuropeptide FF-amide peptide precursor NPFF 8620 NM_003717 /// XM_005269206 0002438 // acute inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003254 // regulation of membrane depolarization // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0030103 // vasopressin secretion // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070253 // somatostatin secretion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214185_at AW592227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW592227 /FEA=EST /DB_XREF=gi:7279403 /DB_XREF=est:hf48a01.x1 /CLONE=IMAGE:2935080 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:U78971.1 AW592227 KH domain containing, RNA binding, signal transduction associated 1 KHDRBS1 10657 NM_001271878 /// NM_006559 /// NR_073498 /// NR_073499 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0031647 // regulation of protein stability // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045948 // positive regulation of translational initiation // inferred from direct assay /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070618 // Grb2-Sos complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214186_s_at AI346483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346483 /FEA=EST /DB_XREF=gi:4083689 /DB_XREF=est:qp51a02.x1 /CLONE=IMAGE:1926506 /UG=Hs.132807 Homo sapiens (clone 3.8-1) MHC class I mRNA fragment AI346483 HLA complex group 26 (non-protein coding) HCG26 352961 NR_002812 214187_x_at AA129726 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129726 /FEA=EST /DB_XREF=gi:1690181 /DB_XREF=est:zl16g09.s1 /CLONE=IMAGE:502144 /UG=Hs.147189 HYA22 protein AA129726 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214188_at AW665096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW665096 /FEA=EST /DB_XREF=gi:7457641 /DB_XREF=est:hi99d03.x1 /CLONE=IMAGE:2980421 /UG=Hs.15299 HMBA-inducible AW665096 214189_s_at AI799984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799984 /FEA=EST /DB_XREF=gi:5365456 /DB_XREF=est:wc46f12.x1 /CLONE=IMAGE:2321711 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 AI799984 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006886 // intracellular protein transport // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 214190_x_at AI799984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI799984 /FEA=EST /DB_XREF=gi:5365456 /DB_XREF=est:wc46f12.x1 /CLONE=IMAGE:2321711 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 AI799984 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 214191_at W67992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W67992 /FEA=EST /DB_XREF=gi:1376931 /DB_XREF=est:zd39h08.r1 /CLONE=IMAGE:343071 /UG=Hs.167927 islet cell autoantigen 1 (69kD) W67992 islet cell autoantigen 1, 69kDa ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 214192_at Y08613 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y08613.1 /DEF=H.sapiens alternative 3 UTR of Nup88 mRNA. /FEA=mRNA /DB_XREF=gi:1707520 /UG=Hs.172108 nucleoporin 88kD Y08613 nucleoporin 88kDa NUP88 4927 NM_002532 /// XM_005256659 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005215 // transporter activity // traceable author statement 214193_s_at AI770084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI770084 /FEA=EST /DB_XREF=gi:5236680 /DB_XREF=est:wi79g10.x1 /CLONE=IMAGE:2399586 /UG=Hs.173381 dihydropyrimidinase-like 2 AI770084 digestive organ expansion factor homolog (zebrafish) DIEXF 27042 NM_014388 /// XM_006711275 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 214194_at AW043622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW043622 /FEA=EST /DB_XREF=gi:5904151 /DB_XREF=est:wy79h02.x1 /CLONE=IMAGE:2554803 /UG=Hs.179566 Human clone 23799 mRNA sequence AW043622 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease DIS3 22894 NM_001128226 /// NM_014953 /// XM_005266294 /// XM_006719778 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016075 // rRNA catabolic process // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071034 // CUT catabolic process // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from mutant phenotype 0000176 // nuclear exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from mutant phenotype /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 214195_at AA602532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA602532 /FEA=EST /DB_XREF=gi:2436466 /DB_XREF=est:no90a08.s1 /CLONE=IMAGE:1114070 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) AA602532 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 214196_s_at AA602532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA602532 /FEA=EST /DB_XREF=gi:2436466 /DB_XREF=est:no90a08.s1 /CLONE=IMAGE:1114070 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) AA602532 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 214197_s_at AI762193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762193 /FEA=EST /DB_XREF=gi:5177860 /DB_XREF=est:wi54a10.x1 /CLONE=IMAGE:2394042 /UG=Hs.20991 SET domain, bifurcated 1 AI762193 SET domain, bifurcated 1 SETDB1 9869 NM_001145415 /// NM_001243491 /// NM_012432 /// XM_005245641 /// XM_006711672 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214198_s_at AU150824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150824 /FEA=EST /DB_XREF=gi:11012345 /DB_XREF=est:AU150824 /CLONE=NT2RP2003689 /UG=Hs.2491 DiGeorge syndrome critical region gene 2 AU150824 DiGeorge syndrome critical region gene 2 DGCR2 9993 NM_001173533 /// NM_001173534 /// NM_001184781 /// NM_005137 /// NR_033674 0007155 // cell adhesion // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 214199_at NM_003019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003019.1 /DEF=Homo sapiens surfactant, pulmonary-associated protein D (SFTPD), mRNA. /FEA=CDS /GEN=SFTPD /PROD=surfactant, pulmonary-associated protein D /DB_XREF=gi:4506908 /UG=Hs.253495 surfactant, pulmonary-associated protein D /FL=gb:NM_003019.1 NM_003019 surfactant protein D SFTPD 6441 NM_003019 0001817 // regulation of cytokine production // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement /// 0043129 // surfactant homeostasis // inferred from mutant phenotype /// 0045085 // negative regulation of interleukin-2 biosynthetic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048246 // macrophage chemotaxis // traceable author statement /// 0048286 // lung alveolus development // inferred from mutant phenotype /// 0050766 // positive regulation of phagocytosis // traceable author statement /// 0072593 // reactive oxygen species metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0030139 // endocytic vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement 214200_s_at AI193744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI193744 /FEA=EST /DB_XREF=gi:3744953 /DB_XREF=est:qe73h10.x1 /CLONE=IMAGE:1744675 /UG=Hs.25459 Homo sapiens, alpha-1 (VI) collagen AI193744 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 214201_x_at AA742237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA742237 /FEA=EST /DB_XREF=gi:2784237 /DB_XREF=est:ny80a09.s1 /CLONE=IMAGE:1284568 /UG=Hs.25911 HLA-B associated transcript-2 AA742237 proline-rich coiled-coil 2A PRRC2A 7916 NM_004638 /// NM_080686 /// XM_006715191 /// XM_006725507 /// XM_006725508 /// XM_006725723 /// XM_006725724 /// XM_006725833 /// XM_006725834 /// XM_006725922 /// XM_006726023 /// XM_006726024 /// XM_006726111 /// XM_006726112 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214202_at N21364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21364 /FEA=EST /DB_XREF=gi:1126534 /DB_XREF=est:yx50h10.s1 /CLONE=IMAGE:265219 /UG=Hs.26968 Homo sapiens mRNA from chromosome 5q21-22, clone:357Ex N21364 CTC-428G20.3 214203_s_at AA074145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA074145 /FEA=EST /DB_XREF=gi:1614015 /DB_XREF=est:zf78g06.s1 /CLONE=IMAGE:383098 /UG=Hs.274550 proline oxidase homolog AA074145 proline dehydrogenase 1, mitochondrial-like /// proline dehydrogenase (oxidase) 1 LOC102724788 /// PRODH 5625 /// 102724788 NM_001195226 /// NM_016335 /// XM_006724935 /// XM_006724936 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006560 // proline metabolic process // traceable author statement /// 0006562 // proline catabolic process // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004657 // proline dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 214204_at BF224076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224076 /FEA=EST /DB_XREF=gi:11131303 /DB_XREF=est:7q83e08.x1 /CLONE=IMAGE:3704942 /UG=Hs.307438 Human DNA sequence from clone 495O10 on chromosome 6q26-27. Contains an RPL37A (60S Ribosomal Protein L37A) pseudogene, the last exon of a gene for a novel protein similar to worm E04F6.2, ESTs, STSs and GSSs BF224076 PARK2 co-regulated PACRG 135138 NM_001080378 /// NM_001080379 /// NM_152410 /// XM_005266824 /// XM_005266825 /// XM_005266826 /// XM_006715343 /// XM_006715344 /// XM_006715345 0007286 // spermatid development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0097225 // sperm midpiece // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 214205_x_at AK022131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022131.1 /DEF=Homo sapiens cDNA FLJ12069 fis, clone HEMBB1002342, highly similar to Homo sapiens PKCq-interacting protein PICOT (PICOT) mRNA. /FEA=mRNA /DB_XREF=gi:10433459 /UG=Hs.42644 thioredoxin-like AK022131 glutaredoxin 3 GLRX3 10539 NM_001199868 /// NM_006541 /// XM_005252657 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 214206_at AI739480 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI739480 /FEA=EST /DB_XREF=gi:5101461 /DB_XREF=est:wi14a12.x1 /CLONE=IMAGE:2390206 /UG=Hs.55235 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) AI739480 peptidylprolyl isomerase (cyclophilin)-like 6 PPIL6 285755 NM_001111298 /// NM_001286360 /// NM_001286361 /// NM_173672 /// NR_104429 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 214207_s_at AW024347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024347 /FEA=EST /DB_XREF=gi:5877877 /DB_XREF=est:wv03b02.x1 /CLONE=IMAGE:2528427 /UG=Hs.57973 hypothetical protein AW024347 caspase recruitment domain family, member 10 CARD10 29775 NM_014550 0006461 // protein complex assembly // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0032449 // CBM complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 214208_at BF448703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448703 /FEA=EST /DB_XREF=gi:11514872 /DB_XREF=est:7n93d02.x1 /CLONE=IMAGE:3572019 /UG=Hs.59728 Homo sapiens mRNA; cDNA DKFZp566C0546 (from clone DKFZp566C0546) BF448703 kelch-like family member 35 KLHL35 283212 NM_001039548 /// NM_173583 214209_s_at BE504895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE504895 /FEA=EST /DB_XREF=gi:9707303 /DB_XREF=est:hz32b07.x1 /CLONE=IMAGE:3209653 /UG=Hs.6129 ATP-binding cassette, sub-family B (MDRTAP), member 9 BE504895 ATP-binding cassette, sub-family B (MDR/TAP), member 9 ABCB9 23457 NM_001243013 /// NM_001243014 /// NM_019624 /// NM_019625 /// NM_203444 /// NM_203445 /// XM_005253558 /// XM_005253559 /// XM_006719314 /// XR_429086 0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from direct assay /// 0055085 // transmembrane transport // not recorded 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015421 // oligopeptide-transporting ATPase activity // /// 0015440 // peptide-transporting ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from direct assay /// 0042288 // MHC class I protein binding // /// 0042605 // peptide antigen binding // /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046978 // TAP1 binding // /// 0046979 // TAP2 binding // /// 0046980 // tapasin binding // 214210_at AL049764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049764 /DEF=Human DNA sequence from clone RP3-362J20 on chromosome 22q13.1-13.31 Contains the 3 part of the gene for peroxisomal integral membrane protein, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:4826548 /UG=Hs.62245 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kD), member 17 AL049764 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 SLC25A17 10478 NM_001282726 /// NM_001282727 /// NM_006358 /// NR_104235 /// NR_104236 /// NR_104237 /// NR_104238 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015866 // ADP transport // inferred from direct assay /// 0015867 // ATP transport // inferred from genetic interaction /// 0015908 // fatty acid transport // inferred from genetic interaction /// 0035349 // coenzyme A transmembrane transport // inferred from direct assay /// 0035350 // FAD transmembrane transport // inferred from direct assay /// 0043132 // NAD transport // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0080121 // AMP transport // inferred from direct assay /// 1901679 // nucleotide transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005347 // ATP transmembrane transporter activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0015217 // ADP transmembrane transporter activity // inferred from direct assay /// 0015228 // coenzyme A transmembrane transporter activity // inferred from direct assay /// 0015230 // FAD transmembrane transporter activity // inferred from direct assay /// 0044610 // FMN transmembrane transporter activity // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051724 // NAD transporter activity // inferred from direct assay /// 0080122 // AMP transmembrane transporter activity // inferred from direct assay 214211_at AA083483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA083483 /FEA=EST /DB_XREF=gi:1625544 /DB_XREF=est:zn32a06.s1 /CLONE=IMAGE:549106 /UG=Hs.62954 ferritin, heavy polypeptide 1 AA083483 ferritin, heavy polypeptide 1 FTH1 2495 NM_002032 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006880 // intracellular sequestering of iron ion // inferred from direct assay /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008043 // intracellular ferritin complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 214212_x_at AI928241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI928241 /FEA=EST /DB_XREF=gi:5664205 /DB_XREF=est:wo95g11.x1 /CLONE=IMAGE:2463140 /UG=Hs.75260 mitogen inducible 2 AI928241 fermitin family member 2 FERMT2 10979 NM_001134999 /// NM_001135000 /// NM_006832 /// XM_005267285 /// XM_006720008 /// XM_006720009 /// XM_006720010 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0033622 // integrin activation // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 214213_x_at AA063189 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA063189 /FEA=EST /DB_XREF=gi:1556923 /DB_XREF=est:zm02e01.s1 /CLONE=IMAGE:512952 /UG=Hs.77886 lamin AC AA063189 lamin A/C LMNA 4000 NM_001257374 /// NM_001282624 /// NM_001282625 /// NM_001282626 /// NM_005572 /// NM_170707 /// NM_170708 0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214214_s_at AU151801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151801 /FEA=EST /DB_XREF=gi:11013322 /DB_XREF=est:AU151801 /CLONE=NT2RP2006128 /UG=Hs.78614 complement component 1, q subcomponent binding protein AU151801 complement component 1, q subcomponent binding protein C1QBP 708 NM_001212 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0039534 // negative regulation of MDA-5 signaling pathway // inferred from direct assay /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070131 // positive regulation of mitochondrial translation // inferred from sequence or structural similarity /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from direct assay /// 0030984 // kininogen binding // inferred from direct assay /// 0031690 // adrenergic receptor binding // inferred from sequence or structural similarity /// 0097177 // mitochondrial ribosome binding // inferred from sequence or structural similarity 214215_s_at AW514174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514174 /FEA=EST /DB_XREF=gi:7152342 /DB_XREF=est:hd24f10.x1 /CLONE=IMAGE:2910475 /UG=Hs.78851 KIAA0217 protein AW514174 La ribonucleoprotein domain family, member 4B LARP4B 23185 NM_015155 /// XM_005252431 /// XM_005252432 /// XM_005252433 /// XM_005252435 /// XM_006717436 0045727 // positive regulation of translation // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 214216_s_at AW628686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW628686 /FEA=EST /DB_XREF=gi:7375566 /DB_XREF=est:hi42e08.x1 /CLONE=IMAGE:2974982 /UG=Hs.78851 KIAA0217 protein AW628686 La ribonucleoprotein domain family, member 4B LARP4B 23185 NM_015155 /// XM_005252431 /// XM_005252432 /// XM_005252433 /// XM_005252435 /// XM_006717436 0006417 // regulation of translation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214217_at D60132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D60132 /FEA=EST /DB_XREF=gi:961771 /DB_XREF=est:HUM087G05A /CLONE=GEN-087G05 /UG=Hs.79981 Human clone 23560 mRNA sequence D60132 glutamate receptor, metabotropic 5 GRM5 2915 NM_000842 /// NM_001143831 /// XM_006718828 /// XM_006718829 /// XM_006718830 0000185 // activation of MAPKKK activity // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // not recorded /// 0007206 // phospholipase C-activating G-protein coupled glutamate receptor signaling pathway // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0040013 // negative regulation of locomotion // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0014069 // postsynaptic density // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation 214218_s_at AV699347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV699347 /FEA=EST /DB_XREF=gi:10301318 /DB_XREF=est:AV699347 /CLONE=GKCBPH07 /UG=Hs.83623 nuclear receptor subfamily 1, group I, member 3 AV699347 X inactive specific transcript (non-protein coding) XIST 7503 NR_001564 214219_x_at BE646618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646618 /FEA=EST /DB_XREF=gi:9970929 /DB_XREF=est:7e91b08.x1 /CLONE=IMAGE:3292503 /UG=Hs.86575 mitogen-activated protein kinase kinase kinase kinase 1 BE646618 mitogen-activated protein kinase kinase kinase kinase 1 MAP4K1 11184 NM_001042600 /// NM_007181 /// XM_006722993 0000185 // activation of MAPKKK activity // inferred by curator /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214220_s_at AW003635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003635 /FEA=EST /DB_XREF=gi:5850551 /DB_XREF=est:wx34e12.x1 /CLONE=IMAGE:2545582 /UG=Hs.97393 KIAA0328 protein AW003635 Alstrom syndrome 1 ALMS1 7840 NM_015120 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214221_at AI825212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825212 /FEA=EST /DB_XREF=gi:5445883 /DB_XREF=est:wb16c10.x1 /CLONE=IMAGE:2305842 /UG=Hs.97393 KIAA0328 protein AI825212 Alstrom syndrome 1 ALMS1 7840 NM_015120 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214222_at AB023161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023161.1 /DEF=Homo sapiens mRNA for KIAA0944 protein, partial cds. /FEA=mRNA /GEN=KIAA0944 /PROD=KIAA0944 protein /DB_XREF=gi:4589531 /UG=Hs.97403 KIAA0944 protein AB023161 dynein, axonemal, heavy chain 7 DNAH7 56171 NM_018897 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0003341 // cilium movement // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 214223_at AA427737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA427737 /FEA=EST /DB_XREF=gi:2111578 /DB_XREF=est:zw30g12.s1 /CLONE=IMAGE:770854 /UG=Hs.110820 ESTs AA427737 protein tyrosine phosphatase type IVA, member 3 PTP4A3 11156 NM_007079 /// NM_032611 /// XM_005250762 /// XM_005250763 /// XM_005250764 /// XM_005250766 /// XM_005250767 /// XM_006716499 /// XM_006716500 /// XM_006725100 /// XM_006725101 /// XM_006725102 /// XM_006725103 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 214224_s_at BE674061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674061 /FEA=EST /DB_XREF=gi:10034602 /DB_XREF=est:7d74a04.x1 /CLONE=IMAGE:3278670 /UG=Hs.11774 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting, 4 (parvulin) BE674061 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) PIN4 5303 NM_001170747 /// NM_006223 /// NR_033187 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030684 // preribosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003681 // bent DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214225_at BE674061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE674061 /FEA=EST /DB_XREF=gi:10034602 /DB_XREF=est:7d74a04.x1 /CLONE=IMAGE:3278670 /UG=Hs.11774 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting, 4 (parvulin) BE674061 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) PIN4 5303 NM_001170747 /// NM_006223 /// NR_033187 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006457 // protein folding // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030684 // preribosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003681 // bent DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214226_at AA528252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA528252 /FEA=EST /DB_XREF=gi:2270321 /DB_XREF=est:nh92c11.s1 /CLONE=IMAGE:965972 /UG=Hs.119273 KIAA0296 gene product AA528252 protease, serine, 53 PRSS53 339105 NM_001039503 /// XM_005255294 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214227_at BF432795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432795 /FEA=EST /DB_XREF=gi:11444958 /DB_XREF=est:7n27a02.x1 /CLONE=IMAGE:3565707 /UG=Hs.127828 guanine nucleotide binding protein (G protein), gamma 7 BF432795 214228_x_at AJ277151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ277151 /DEF=Homo sapiens ox40 gene for CD134 antigen, exons 1-7 /FEA=mRNA /DB_XREF=gi:8926701 /UG=Hs.129780 tumor necrosis factor receptor superfamily, member 4 AJ277151 tumor necrosis factor receptor superfamily, member 4 TNFRSF4 7293 NM_003327 /// XM_005244794 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005031 // tumor necrosis factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214229_at AL122077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122077.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H2450 (from clone DKFZp434H2450). /FEA=mRNA /GEN=DKFZp434H2450 /PROD=hypothetical protein /DB_XREF=gi:6102879 /UG=Hs.144672 dynein, axonemal, heavy polypeptide 17 AL122077 dynein, axonemal, heavy chain 17 DNAH17 8632 NM_003727 /// NM_173628 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation 214230_at R37664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R37664 /FEA=EST /DB_XREF=gi:795120 /DB_XREF=est:yf61e05.s1 /CLONE=IMAGE:26577 /UG=Hs.146409 cell division cycle 42 (GTP-binding protein, 25kD) R37664 cell division cycle 42 CDC42 998 NM_001039802 /// NM_001791 /// NM_044472 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from physical interaction /// 0031424 // keratinization // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048554 // positive regulation of metalloenzyme activity // inferred from electronic annotation /// 0048664 // neuron fate determination // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0051647 // nucleus localization // inferred from electronic annotation /// 0051683 // establishment of Golgi localization // inferred from sequence or structural similarity /// 0051835 // positive regulation of synapse structural plasticity // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0060047 // heart contraction // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060661 // submandibular salivary gland formation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from electronic annotation /// 0071338 // positive regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0072384 // organelle transport along microtubule // inferred from sequence or structural similarity /// 0090135 // actin filament branching // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 214231_s_at AI744626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744626 /FEA=EST /DB_XREF=gi:5113003 /DB_XREF=est:wg04g04.x1 /CLONE=IMAGE:2364150 /UG=Hs.151385 KIAA0564 protein AI744626 von Willebrand factor A domain containing 8 VWA8 23078 NM_001009814 /// NM_015058 /// XM_006719790 /// XM_006719791 /// XM_006719792 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 214232_at AL037534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037534 /FEA=EST /DB_XREF=gi:5866521 /DB_XREF=est:DKFZp564F2472_r1 /CLONE=DKFZp564F2472 /UG=Hs.153612 ATP-binding cassette, sub-family F (GCN20), member 2 AL037534 ATP-binding cassette, sub-family F (GCN20), member 2 ABCF2 10061 NM_005692 /// NM_007189 /// XM_005249931 /// XM_006715824 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 214233_at AW086154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW086154 /FEA=EST /DB_XREF=gi:6041228 /DB_XREF=est:xc77c06.x1 /CLONE=IMAGE:2590282 /UG=Hs.155546 KIAA1080 protein; Golgi-associated, gamma-adaptin ear containing, ARF-binding protein 2 AW086154 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 GGA2 23062 NM_015044 /// XR_429674 0006886 // intracellular protein transport // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from direct assay 214234_s_at X90579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X90579.1 /DEF=H.sapiens DNA for cyp related pseudogene. /FEA=mRNA /DB_XREF=gi:945005 /UG=Hs.166079 H.sapiens DNA for cyp related pseudogene X90579 cytochrome P450, family 3, subfamily A, polypeptide 5 CYP3A5 1577 NM_000777 /// NM_001190484 /// NM_001291829 /// NM_001291830 /// NR_033807 /// NR_033808 /// NR_033809 /// NR_033810 /// NR_033811 /// NR_033812 /// XM_006715859 /// XM_006715860 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070989 // oxidative demethylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 214235_at X90579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X90579.1 /DEF=H.sapiens DNA for cyp related pseudogene. /FEA=mRNA /DB_XREF=gi:945005 /UG=Hs.166079 H.sapiens DNA for cyp related pseudogene X90579 cytochrome P450, family 3, subfamily A, polypeptide 5 CYP3A5 1577 NM_000777 /// NM_001190484 /// NM_001291829 /// NM_001291830 /// NR_033807 /// NR_033808 /// NR_033809 /// NR_033810 /// NR_033811 /// NR_033812 /// XM_006715859 /// XM_006715860 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070989 // oxidative demethylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from sequence or structural similarity /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 214236_at AA166684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA166684 /FEA=EST /DB_XREF=gi:1745139 /DB_XREF=est:zq41g06.s1 /CLONE=IMAGE:632314 /UG=Hs.172405 cell division cycle 27 AA166684 214237_x_at AI760470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI760470 /FEA=EST /DB_XREF=gi:5176137 /DB_XREF=est:wi51h05.x1 /CLONE=IMAGE:2393817 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator AI760470 PRKC, apoptosis, WT1, regulator PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 214238_at AI093572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI093572 /FEA=EST /DB_XREF=gi:3432548 /DB_XREF=est:qb15f11.x1 /CLONE=IMAGE:1696365 /UG=Hs.18081 Homo sapiens clone DT1P1B6 mRNA, CAG repeat region AI093572 AC012065.7 214239_x_at AI560455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI560455 /FEA=EST /DB_XREF=gi:4510796 /DB_XREF=est:tn11b01.x1 /CLONE=IMAGE:2167273 /UG=Hs.184669 zinc finger protein 144 (Mel-18) AI560455 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214240_at AL556409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL556409 /FEA=EST /DB_XREF=gi:12899058 /DB_XREF=est:AL556409 /CLONE=CS0DK004YA08 (5 prime) /UG=Hs.1907 galanin AL556409 galanin/GMAP prepropeptide GAL 51083 NM_015973 /// XM_006718580 0006939 // smooth muscle contraction // non-traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010737 // protein kinase A signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030073 // insulin secretion // non-traceable author statement /// 0030252 // growth hormone secretion // non-traceable author statement /// 0031943 // regulation of glucocorticoid metabolic process // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0051464 // positive regulation of cortisol secretion // inferred from direct assay /// 0051795 // positive regulation of catagen // inferred from direct assay /// 1902608 // positive regulation of large conductance calcium-activated potassium channel activity // inferred from direct assay /// 1902891 // negative regulation of root hair elongation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031764 // type 1 galanin receptor binding // inferred from direct assay /// 0031765 // type 2 galanin receptor binding // inferred from direct assay /// 0031766 // type 3 galanin receptor binding // inferred from direct assay 214241_at AA723057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA723057 /FEA=EST /DB_XREF=gi:2740764 /DB_XREF=est:zg83b10.s1 /CLONE=IMAGE:399931 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) AA723057 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa NDUFB8 4714 NM_001284367 /// NM_001284368 /// NM_005004 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 214242_at AI189305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189305 /FEA=EST /DB_XREF=gi:3740514 /DB_XREF=est:qd05d11.x1 /CLONE=IMAGE:1722837 /UG=Hs.239114 mannosidase, alpha, class 1A, member 2 AI189305 mannosidase, alpha, class 1A, member 2 MAN1A2 10905 NM_006699 /// XM_006710302 0006491 // N-glycan processing // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 214243_s_at AL450314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL450314.1 /DEF=Novel human gene mapping to chomosome 22. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:11322747 /UG=Hs.239934 CGI-96 protein AL450314 serine hydrolase-like /// serine hydrolase-like 2 SERHL /// SERHL2 94009 /// 253190 NM_001284334 /// NM_014509 /// NM_170694 /// NR_027786 /// NR_104300 /// NR_104301 /// XM_006724222 /// XR_244363 /// XR_430405 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 214244_s_at AV717561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV717561 /FEA=EST /DB_XREF=gi:10814713 /DB_XREF=est:AV717561 /CLONE=DCBARG05 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD AV717561 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 214245_at AI734124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI734124 /FEA=EST /DB_XREF=gi:5055237 /DB_XREF=est:zv47g03.y5 /CLONE=IMAGE:756820 /UG=Hs.244621 ribosomal protein S14 AI734124 ribosomal protein S14 RPS14 6208 NM_001025070 /// NM_001025071 /// NM_005617 /// XM_006714790 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000028 // ribosomal small subunit assembly // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from sequence or structural similarity /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 214246_x_at AI859060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI859060 /FEA=EST /DB_XREF=gi:5512676 /DB_XREF=est:wl66d06.x1 /CLONE=IMAGE:2429867 /UG=Hs.278295 cholinergic receptor, nicotinic, epsilon polypeptide AI859060 misshapen-like kinase 1 MINK1 50488 NM_001024937 /// NM_015716 /// NM_153827 /// NM_170663 /// XM_005256664 /// XM_005256665 /// XM_005256666 /// XM_006721530 /// XM_006721531 /// XM_006721532 /// XM_006721533 /// XM_006721534 /// XM_006721535 /// XM_006721536 /// XM_006721537 /// XM_006721538 0001952 // regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214247_s_at AU148057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148057 /FEA=EST /DB_XREF=gi:11009578 /DB_XREF=est:AU148057 /CLONE=MAMMA1002489 /UG=Hs.278503 regulated in glioma AU148057 dickkopf WNT signaling pathway inhibitor 3 DKK3 27122 NM_001018057 /// NM_013253 /// NM_015881 /// XM_006718177 /// XM_006718178 /// XM_006718179 /// XM_006718180 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from expression pattern /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 214248_s_at AW071795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW071795 /FEA=EST /DB_XREF=gi:6026720 /DB_XREF=est:ws53f10.x1 /CLONE=IMAGE:2500939 /UG=Hs.300366 Homo sapiens cDNA FLJ20172 fis, clone COL09807 AW071795 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214249_at AK000179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000179.1 /DEF=Homo sapiens cDNA FLJ20172 fis, clone COL09807. /FEA=mRNA /DB_XREF=gi:7020095 /UG=Hs.300366 Homo sapiens cDNA FLJ20172 fis, clone COL09807 AK000179 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214250_at AI337584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI337584 /FEA=EST /DB_XREF=gi:4074511 /DB_XREF=est:qw91a01.x1 /CLONE=IMAGE:1998408 /UG=Hs.301512 nuclear mitotic apparatus protein 1 AI337584 nuclear mitotic apparatus protein 1 NUMA1 4926 NM_001286561 /// NM_006185 /// NR_104476 /// XM_006718562 /// XM_006718563 /// XM_006718564 /// XM_006718565 /// XM_006718566 /// XM_006718567 /// XM_006718568 /// XM_006718569 /// XM_006718570 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006997 // nucleus organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation 214251_s_at AI337584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI337584 /FEA=EST /DB_XREF=gi:4074511 /DB_XREF=est:qw91a01.x1 /CLONE=IMAGE:1998408 /UG=Hs.301512 nuclear mitotic apparatus protein 1 AI337584 nuclear mitotic apparatus protein 1 NUMA1 4926 NM_001286561 /// NM_006185 /// NR_104476 /// XM_006718562 /// XM_006718563 /// XM_006718564 /// XM_006718565 /// XM_006718566 /// XM_006718567 /// XM_006718568 /// XM_006718569 /// XM_006718570 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006997 // nucleus organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation 214252_s_at AV700514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700514 /FEA=EST /DB_XREF=gi:10302485 /DB_XREF=est:AV700514 /CLONE=GKCDQC04 /UG=Hs.30213 ceroid-lipofuscinosis, neuronal 5 AV700514 ceroid-lipofuscinosis, neuronal 5 CLN5 1203 NM_006493 0006465 // signal peptide processing // inferred from direct assay /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007601 // visual perception // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from expression pattern /// 0030163 // protein catabolic process // non-traceable author statement /// 0042551 // neuron maturation // non-traceable author statement /// 0070085 // glycosylation // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005775 // vacuolar lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay 214253_s_at AI672185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI672185 /FEA=EST /DB_XREF=gi:4851916 /DB_XREF=est:tz10e11.x1 /CLONE=IMAGE:2288204 /UG=Hs.326682 Homo sapiens dystrobrevin, beta (DTNB), mRNA AI672185 dystrobrevin, beta DTNB 1838 NM_001256303 /// NM_001256304 /// NM_001256308 /// NM_021907 /// NM_033147 /// NM_033148 /// NM_183360 /// NM_183361 /// XM_005264182 /// XM_005264183 /// XM_005264184 /// XM_005264186 /// XM_006711960 /// XM_006711961 /// XM_006711962 0005737 // cytoplasm // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214254_at AW438674 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW438674 /FEA=EST /DB_XREF=gi:6973980 /DB_XREF=est:xt02b04.x1 /CLONE=IMAGE:2777935 /UG=Hs.37107 melanoma antigen, family A, 4 /FL=gb:D32075.1 gb:D32077.1 gb:NM_002362.1 gb:U10340.1 AW438674 melanoma antigen family A, 4 MAGEA4 4103 NM_001011548 /// NM_001011549 /// NM_001011550 /// NM_002362 /// XM_005274677 /// XM_005274678 /// XM_005274679 0005515 // protein binding // inferred from physical interaction 214255_at N35112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N35112 /FEA=EST /DB_XREF=gi:1156254 /DB_XREF=est:yy19h05.s1 /CLONE=IMAGE:271737 /UG=Hs.44697 ATPase, Class V, type 10C N35112 ATPase, class V, type 10A ATP10A 57194 NM_024490 /// XM_005268261 /// XM_006720619 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // non-traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214256_at AB011138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011138.1 /DEF=Homo sapiens mRNA for KIAA0566 protein, partial cds. /FEA=mRNA /GEN=KIAA0566 /PROD=KIAA0566 protein /DB_XREF=gi:3043655 /UG=Hs.44697 ATPase, Class V, type 10C AB011138 ATPase, class V, type 10A ATP10A 57194 NM_024490 /// XM_005268261 /// XM_006720619 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // non-traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214257_s_at AA890010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA890010 /FEA=EST /DB_XREF=gi:3016889 /DB_XREF=est:aj89h08.s1 /CLONE=IMAGE:1403679 /UG=Hs.50785 SEC22, vesicle trafficking protein (S. cerevisiae)-like 1 AA890010 SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) SEC22B 9554 NM_004892 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214258_x_at AA886971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA886971 /FEA=EST /DB_XREF=gi:3002079 /DB_XREF=est:oi14g06.s1 /CLONE=IMAGE:1476538 /UG=Hs.6364 HIV-1 Tat interactive protein, 60 kDa AA886971 K(lysine) acetyltransferase 5 KAT5 10524 NM_001206833 /// NM_006388 /// NM_182709 /// NM_182710 /// XM_006718421 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction 214259_s_at AI144075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI144075 /FEA=EST /DB_XREF=gi:3665884 /DB_XREF=est:qi63e12.x1 /CLONE=IMAGE:1861198 /UG=Hs.6980 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) AI144075 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) AKR7A2 8574 NM_003689 0005975 // carbohydrate metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019119 // phenanthrene-9,10-epoxide hydrolase activity // inferred from direct assay 214260_at AI079287 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI079287 /FEA=EST /DB_XREF=gi:3415538 /DB_XREF=est:oz32h07.x1 /CLONE=IMAGE:1677085 /UG=Hs.75193 COP9 homolog AI079287 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 214261_s_at H71135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H71135 /FEA=EST /DB_XREF=gi:1042951 /DB_XREF=est:ys13e09.s1 /CLONE=IMAGE:214696 /UG=Hs.76800 alcohol dehydrogenase 6 (class V) H71135 alcohol dehydrogenase 6 (class V) ADH6 130 NM_000672 /// NM_001102470 /// XM_005262731 /// XR_244619 0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004022 // alcohol dehydrogenase (NAD) activity // inferred from direct assay /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0035276 // ethanol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214262_at BE964082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964082 /FEA=EST /DB_XREF=gi:11767550 /DB_XREF=est:601657561R1 /CLONE=IMAGE:3875799 /UG=Hs.78614 complement component 1, q subcomponent binding protein BE964082 microRNA 6875 /// thyroid hormone receptor interactor 6 MIR6875 /// TRIP6 7205 /// 102466755 NM_003302 /// NR_106935 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008588 // release of cytoplasmic sequestered NF-kappaB // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045323 // interleukin-1 receptor complex // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // non-traceable author statement 214263_x_at AI192781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI192781 /FEA=EST /DB_XREF=gi:3743990 /DB_XREF=est:qe67e09.x1 /CLONE=IMAGE:1744072 /UG=Hs.79402 polymerase (RNA) II (DNA directed) polypeptide C (33kD) AI192781 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa POLR2C 5432 NM_002694 /// NM_032940 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 214264_s_at AI656610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI656610 /FEA=EST /DB_XREF=gi:4740589 /DB_XREF=est:tt46h03.x1 /CLONE=IMAGE:2243861 /UG=Hs.87819 Homo sapiens, clone MGC:2492, mRNA, complete cds AI656610 EF-hand calcium binding domain 11 EFCAB11 90141 NM_001284266 /// NM_001284267 /// NM_001284268 /// NM_001284269 /// NM_145231 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214265_at AI193623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI193623 /FEA=EST /DB_XREF=gi:3744832 /DB_XREF=est:qe71d07.x1 /CLONE=IMAGE:1744429 /UG=Hs.91296 integrin, alpha 8 AI193623 integrin, alpha 8 ITGA8 8516 NM_001291494 /// NM_003638 /// XM_005252633 0001656 // metanephros development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 2000721 // positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 214266_s_at AW206786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW206786 /FEA=EST /DB_XREF=gi:6506282 /DB_XREF=est:UI-H-BI1-afq-g-11-0-UI.s1 /CLONE=IMAGE:2722772 /UG=Hs.102948 enigma (LIM domain protein) AW206786 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214267_s_at AI050793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI050793 /FEA=EST /DB_XREF=gi:3307598 /DB_XREF=est:ov12b09.x1 /CLONE=IMAGE:1637081 /UG=Hs.129064 Homo sapiens chromosome 19, cosmid F22162 AI050793 cell adhesion molecule 4 CADM4 199731 NM_145296 /// XM_005258620 0007155 // cell adhesion // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 214268_s_at AL042220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL042220 /FEA=EST /DB_XREF=gi:5421564 /DB_XREF=est:DKFZp434H1920_s1 /CLONE=DKFZp434H1920 /UG=Hs.141727 myotubularin related protein 4 AL042220 myotubularin related protein 4 MTMR4 9110 NM_004687 /// XM_005257784 /// XM_005257785 /// XM_005257786 /// XM_006722168 0006470 // protein dephosphorylation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214269_at AK025922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025922.1 /DEF=Homo sapiens cDNA: FLJ22269 fis, clone HRC03179. /FEA=mRNA /DB_XREF=gi:10438586 /UG=Hs.170482 myosin, light polypeptide 5, regulatory AK025922 major facilitator superfamily domain containing 7 MFSD7 84179 NM_001294341 /// NM_001294342 /// NM_032219 /// XM_005272295 /// XM_005272297 /// XM_005272299 /// XM_006713918 /// XM_006713919 /// XR_246613 /// XR_427480 /// XR_427481 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214270_s_at AI885178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885178 /FEA=EST /DB_XREF=gi:5590342 /DB_XREF=est:wl90f07.x1 /CLONE=IMAGE:2432197 /UG=Hs.172740 microtubule-associated protein, RPEB family, member 3 AI885178 microtubule-associated protein, RP/EB family, member 3 MAPRE3 22924 NM_012326 /// XM_006711967 /// XM_006711968 0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 214271_x_at AA281332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA281332 /FEA=EST /DB_XREF=gi:1924013 /DB_XREF=est:zs93h10.s1 /CLONE=IMAGE:705091 /UG=Hs.182979 ribosomal protein L12 AA281332 ribosomal protein L12 RPL12 6136 NM_000976 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214272_at AI362018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI362018 /FEA=EST /DB_XREF=gi:4113639 /DB_XREF=est:qy39a11.x1 /CLONE=IMAGE:2014364 /UG=Hs.18827 KIAA0849 protein AI362018 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 214273_x_at AV704353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV704353 /FEA=EST /DB_XREF=gi:10721671 /DB_XREF=est:AV704353 /CLONE=ADBCNG09 /UG=Hs.19699 Conserved gene telomeric to alpha globin cluster AV704353 nitrogen permease regulator-like 3 (S. cerevisiae) NPRL3 8131 NM_001039476 /// NM_001077350 /// NM_001243247 /// NM_001243248 /// NM_001243249 /// NM_012075 0003281 // ventricular septum development // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation 214274_s_at AI860341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI860341 /FEA=EST /DB_XREF=gi:5513957 /DB_XREF=est:wl02a03.x1 /CLONE=IMAGE:2423692 /UG=Hs.200188 deleted in lung and esophageal cancer 1 AI860341 acetyl-CoA acyltransferase 1 ACAA1 30 NM_001130410 /// NM_001607 /// NR_024024 /// XM_006713122 /// XM_006713123 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from mutant phenotype /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016401 // palmitoyl-CoA oxidase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 214275_at AI217362 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI217362 /FEA=EST /DB_XREF=gi:3797177 /DB_XREF=est:qh17b10.x1 /CLONE=IMAGE:1844923 /UG=Hs.211607 trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) AI217362 mediator complex subunit 12 MED12 9968 NM_005120 /// XM_005262317 /// XM_005262319 0001843 // neural tube closure // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090245 // axis elongation involved in somitogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 214276_at N49268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N49268 /FEA=EST /DB_XREF=gi:1190434 /DB_XREF=est:yy85e11.s1 /CLONE=IMAGE:280364 /UG=Hs.23510 Kruppel-like factor 12 N49268 Kruppel-like factor 12 KLF12 11278 NM_007249 /// NM_016285 /// XM_005266251 /// XM_005266252 /// XM_006719762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214277_at AI376724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI376724 /FEA=EST /DB_XREF=gi:4186577 /DB_XREF=est:tc35f05.x1 /CLONE=IMAGE:2066625 /UG=Hs.241515 COX11 (yeast) homolog, cytochrome c oxidase assembly protein AI376724 cytochrome c oxidase assembly homolog 11 (yeast) COX11 1353 NM_001162861 /// NM_001162862 /// NM_004375 /// NR_027941 /// NR_027942 /// XM_006721704 /// XM_006721705 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 214278_s_at AI358939 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI358939 /FEA=EST /DB_XREF=gi:4110560 /DB_XREF=est:qy24f03.x1 /CLONE=IMAGE:2012957 /UG=Hs.243960 N-myc downstream-regulated gene 2 AI358939 NDRG family member 2 NDRG2 57447 NM_001282211 /// NM_001282212 /// NM_001282213 /// NM_001282214 /// NM_001282215 /// NM_001282216 /// NM_016250 /// NM_201535 /// NM_201536 /// NM_201537 /// NM_201538 /// NM_201539 /// NM_201540 /// NM_201541 /// XM_005267892 /// XM_005267893 /// XM_005267894 /// XM_005267895 /// XM_005267896 /// XM_005267898 /// XM_005267899 /// XM_005267900 /// XM_005267901 /// XM_005267902 /// XM_005267903 /// XM_005267904 /// XM_005267905 /// XM_005267911 0001818 // negative regulation of cytokine production // inferred from electronic annotation /// 0010574 // regulation of vascular endothelial growth factor production // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0090361 // regulation of platelet-derived growth factor production // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0030426 // growth cone // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214279_s_at W74452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W74452 /FEA=EST /DB_XREF=gi:1384878 /DB_XREF=est:zd77b12.s1 /CLONE=IMAGE:346655 /UG=Hs.243960 N-myc downstream-regulated gene 2 W74452 NDRG family member 2 NDRG2 57447 NM_001282211 /// NM_001282212 /// NM_001282213 /// NM_001282214 /// NM_001282215 /// NM_001282216 /// NM_016250 /// NM_201535 /// NM_201536 /// NM_201537 /// NM_201538 /// NM_201539 /// NM_201540 /// NM_201541 /// XM_005267892 /// XM_005267893 /// XM_005267894 /// XM_005267895 /// XM_005267896 /// XM_005267898 /// XM_005267899 /// XM_005267900 /// XM_005267901 /// XM_005267902 /// XM_005267903 /// XM_005267904 /// XM_005267905 /// XM_005267911 0001818 // negative regulation of cytokine production // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010574 // regulation of vascular endothelial growth factor production // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0090361 // regulation of platelet-derived growth factor production // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214280_x_at X79536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79536.1 /DEF=H.sapiens mRNA for hnRNPcore protein A1. /FEA=mRNA /PROD=hnRNPcore protein A1 /DB_XREF=gi:496897 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 X79536 heterogeneous nuclear ribonucleoprotein A1 HNRNPA1 3178 NM_002136 /// NM_031157 /// XM_005268826 /// XR_245923 /// XR_245924 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214281_s_at AA524525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524525 /FEA=EST /DB_XREF=gi:2265453 /DB_XREF=est:ng44h03.s1 /CLONE=IMAGE:937685 /UG=Hs.279864 PRO1996 protein AA524525 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase RCHY1 25898 NM_001008925 /// NM_001009922 /// NM_001278536 /// NM_001278537 /// NM_001278538 /// NM_001278539 /// NM_015436 /// NR_037913 /// NR_037914 /// NR_103723 /// NR_103724 /// NR_103725 /// XM_006714174 0016567 // protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214282_at AA191647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA191647 /FEA=EST /DB_XREF=gi:1780377 /DB_XREF=est:zp82a10.s1 /CLONE=IMAGE:626682 /UG=Hs.296634 ceruloplasmin (ferroxidase) AA191647 214283_at AU150186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150186 /FEA=EST /DB_XREF=gi:11011707 /DB_XREF=est:AU150186 /CLONE=NT2RP2001860 /UG=Hs.4187 hypothetical protein 24636 AU150186 transmembrane protein 97 TMEM97 27346 NM_014573 /// XM_005257965 0001558 // regulation of cell growth // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214284_s_at AA022949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA022949 /FEA=EST /DB_XREF=gi:1487039 /DB_XREF=est:ze72h02.s1 /CLONE=IMAGE:364563 /UG=Hs.49585 fibroblast growth factor 18 AA022949 fibroblast growth factor 18 FGF18 8817 NM_003862 /// NM_033649 0001525 // angiogenesis // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 214285_at AI041520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI041520 /FEA=EST /DB_XREF=gi:3280714 /DB_XREF=est:ov82a04.x1 /CLONE=IMAGE:1643790 /UG=Hs.49881 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) AI041520 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) FABP3 2170 NM_004102 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0044539 // long-chain fatty acid import // inferred from sequence or structural similarity /// 0046320 // regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071073 // positive regulation of phospholipid biosynthetic process // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016528 // sarcoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005324 // long-chain fatty acid transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0036041 // long-chain fatty acid binding // inferred from direct assay /// 0050543 // icosatetraenoic acid binding // inferred from electronic annotation /// 0070538 // oleic acid binding // inferred from direct assay 214286_at X63749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63749 /DEF=H.sapiens DNA for Rod transducin alpha-subunit /FEA=mRNA /DB_XREF=gi:37049 /UG=Hs.51147 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 X63749 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 GNAT1 2779 NM_000172 /// NM_144499 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007601 // visual perception // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // inferred from mutant phenotype /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009642 // response to light intensity // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from mutant phenotype /// 0050917 // sensory perception of umami taste // not recorded /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0000035 // acyl binding // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 214287_s_at BE675449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE675449 /FEA=EST /DB_XREF=gi:10035990 /DB_XREF=est:7f09c08.x1 /CLONE=IMAGE:3294158 /UG=Hs.59498 cell division cycle 2-like 5 (cholinesterase-related cell division controller) BE675449 cyclin-dependent kinase 13 CDK13 8621 NM_003718 /// NM_031267 0000380 // alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0000380 // alternative mRNA splicing, via spliceosome // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0004672 // protein kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0030332 // cyclin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214288_s_at W86293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W86293 /FEA=EST /DB_XREF=gi:1398731 /DB_XREF=est:zh54c06.s1 /CLONE=IMAGE:415882 /UG=Hs.75748 proteasome (prosome, macropain) subunit, beta type, 1 W86293 proteasome (prosome, macropain) subunit, beta type, 1 PSMB1 5689 NM_002793 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214289_at W86293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W86293 /FEA=EST /DB_XREF=gi:1398731 /DB_XREF=est:zh54c06.s1 /CLONE=IMAGE:415882 /UG=Hs.75748 proteasome (prosome, macropain) subunit, beta type, 1 W86293 proteasome (prosome, macropain) subunit, beta type, 1 PSMB1 5689 NM_002793 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214290_s_at AI313324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI313324 /FEA=EST /DB_XREF=gi:4018929 /DB_XREF=est:ta77f02.x2 /CLONE=IMAGE:2050107 /UG=Hs.795 H2A histone family, member O AI313324 histone cluster 2, H2aa3 /// histone cluster 2, H2aa4 HIST2H2AA3 /// HIST2H2AA4 8337 /// 723790 NM_001040874 /// NM_003516 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214291_at AA522618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA522618 /FEA=EST /DB_XREF=gi:2263330 /DB_XREF=est:ni38h08.s1 /CLONE=IMAGE:979167 /UG=Hs.82202 ribosomal protein L17 AA522618 ribosomal protein L17 /// RPL17-C18orf32 readthrough /// small nucleolar RNA, C/D box 58A /// small nucleolar RNA, C/D box 58B /// small nucleolar RNA, C/D box 58C RPL17 /// RPL17-C18orf32 /// SNORD58A /// SNORD58B /// SNORD58C 6139 /// 26790 /// 26791 /// 100124516 /// 100526842 NM_000985 /// NM_001035006 /// NM_001199340 /// NM_001199341 /// NM_001199342 /// NM_001199343 /// NM_001199344 /// NM_001199345 /// NM_001199355 /// NM_001199356 /// NR_002571 /// NR_002572 /// NR_003701 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 214292_at AA808063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA808063 /FEA=EST /DB_XREF=gi:2877469 /DB_XREF=est:of50f09.s1 /CLONE=IMAGE:1427657 /UG=Hs.85266 integrin, beta 4 AA808063 integrin, beta 4 ITGB4 3691 NM_000213 /// NM_001005619 /// NM_001005731 /// XM_005257309 /// XM_005257311 /// XM_005257312 /// XM_006721866 /// XM_006721867 /// XM_006721868 /// XM_006721869 /// XM_006721870 0006914 // autophagy // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214293_at AI539361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI539361 /FEA=EST /DB_XREF=gi:4453496 /DB_XREF=est:te51b05.x1 /CLONE=IMAGE:2090193 /UG=Hs.8768 hypothetical protein FLJ10849 AI539361 septin 11 SEPT11 55752 NM_018243 /// XM_005263120 /// XM_005263121 /// XM_005263122 /// XM_006714259 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 214294_at AI122905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI122905 /FEA=EST /DB_XREF=gi:3538671 /DB_XREF=est:ok31a12.s1 /CLONE=IMAGE:1509406 /UG=Hs.89121 KIAA0485 protein AI122905 uncharacterized LOC57235 KIAA0485 57235 214295_at AW129056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW129056 /FEA=EST /DB_XREF=gi:6117000 /DB_XREF=est:xe94f04.x1 /CLONE=IMAGE:2615551 /UG=Hs.89121 KIAA0485 protein AW129056 uncharacterized LOC57235 KIAA0485 57235 214296_x_at AV721013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV721013 /FEA=EST /DB_XREF=gi:10818165 /DB_XREF=est:AV721013 /CLONE=HTBBHG06 /UG=Hs.90010 Homo sapiens chromosome 19, cosmid R26660 AV721013 IZUMO family member 4 IZUMO4 113177 NM_001031735 /// NM_001039846 /// NM_052878 /// XM_005259480 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 214297_at BE857703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE857703 /FEA=EST /DB_XREF=gi:10371993 /DB_XREF=est:7g46a02.x1 /CLONE=IMAGE:3309482 /UG=Hs.9004 chondroitin sulfate proteoglycan 4 (melanoma-associated) BE857703 chondroitin sulfate proteoglycan 4 CSPG4 1464 NM_001897 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 214298_x_at AL568374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL568374 /FEA=EST /DB_XREF=gi:12922649 /DB_XREF=est:AL568374 /CLONE=CS0DE001YI09 (3 prime) /UG=Hs.90998 KIAA0128 protein; septin 2 AL568374 septin 6 SEPT6 23157 NM_015129 /// NM_145799 /// NM_145800 /// NM_145802 /// XM_005262400 /// XM_006724748 /// XM_006724749 /// XM_006724750 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement 214299_at AI676092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI676092 /FEA=EST /DB_XREF=gi:4876572 /DB_XREF=est:wc05c06.x1 /CLONE=IMAGE:2314282 /UG=Hs.91175 topoisomerase (DNA) III alpha AI676092 topoisomerase (DNA) III alpha TOP3A 7156 NM_004618 /// XM_005256776 /// XM_005256777 0006265 // DNA topological change // inferred from direct assay /// 0007126 // meiotic nuclear division // traceable author statement 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003917 // DNA topoisomerase type I activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214300_s_at AI676092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI676092 /FEA=EST /DB_XREF=gi:4876572 /DB_XREF=est:wc05c06.x1 /CLONE=IMAGE:2314282 /UG=Hs.91175 topoisomerase (DNA) III alpha AI676092 topoisomerase (DNA) III alpha TOP3A 7156 NM_004618 /// XM_005256776 /// XM_005256777 0006265 // DNA topological change // inferred from direct assay /// 0007126 // meiotic nuclear division // traceable author statement 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003917 // DNA topoisomerase type I activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214301_s_at AI857455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI857455 /FEA=EST /DB_XREF=gi:5511071 /DB_XREF=est:wl57d09.x1 /CLONE=IMAGE:2429009 /UG=Hs.100058 dihydropyrimidinase-like 4 AI857455 dihydropyrimidinase-like 4 DPYSL4 10570 NM_006426 /// XM_005252658 /// XM_005252659 /// XM_006717547 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005829 // cytosol // traceable author statement 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 214302_x_at BF061637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF061637 /FEA=EST /DB_XREF=gi:10820547 /DB_XREF=est:7i82c02.x1 /CLONE=IMAGE:3341186 /UG=Hs.100072 connexin46.6 BF061637 gap junction protein, gamma 2, 47kDa GJC2 57165 NM_020435 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005922 // connexon complex // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0005243 // gap junction channel activity // inferred from electronic annotation 214303_x_at AW192795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW192795 /FEA=EST /DB_XREF=gi:6471494 /DB_XREF=est:xl51d08.x1 /CLONE=IMAGE:2678223 /UG=Hs.103707 apomucin AW192795 mucin 5AC, oligomeric mucus/gel-forming MUC5AC 4586 NM_017511 /// XM_006709945 /// XM_006709947 /// XM_006718399 /// XM_006726526 /// XM_006726528 0016266 // O-glycan processing // traceable author statement /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043205 // fibril // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement 214304_x_at AI077476 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI077476 /FEA=EST /DB_XREF=gi:3411884 /DB_XREF=est:oz49b01.x1 /CLONE=IMAGE:1678633 /UG=Hs.10587 KIAA0353 protein AI077476 RP11-654A16.3 214305_s_at AW003030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003030 /FEA=EST /DB_XREF=gi:5849868 /DB_XREF=est:wq61e04.x1 /CLONE=IMAGE:2475774 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD AW003030 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214306_at AA209332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA209332 /FEA=EST /DB_XREF=gi:1807276 /DB_XREF=est:zq82d12.s1 /CLONE=IMAGE:648119 /UG=Hs.147946 optic atrophy 1 (autosomal dominant) AA209332 optic atrophy 1 (autosomal dominant) OPA1 4976 NM_015560 /// NM_130831 /// NM_130832 /// NM_130833 /// NM_130834 /// NM_130835 /// NM_130836 /// NM_130837 0000266 // mitochondrial fission // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007005 // mitochondrion organization // non-traceable author statement /// 0007007 // inner mitochondrial membrane organization // inferred from direct assay /// 0007601 // visual perception // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0090398 // cellular senescence // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214307_at AI478172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478172 /FEA=EST /DB_XREF=gi:4371398 /DB_XREF=est:tm50a05.x1 /CLONE=IMAGE:2161520 /UG=Hs.15113 homogentisate 1,2-dioxygenase (homogentisate oxidase) AI478172 homogentisate 1,2-dioxygenase HGD 3081 NM_000187 /// XM_005247412 /// XM_005247413 /// XM_005247414 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004411 // homogentisate 1,2-dioxygenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 214308_s_at AI478172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478172 /FEA=EST /DB_XREF=gi:4371398 /DB_XREF=est:tm50a05.x1 /CLONE=IMAGE:2161520 /UG=Hs.15113 homogentisate 1,2-dioxygenase (homogentisate oxidase) AI478172 homogentisate 1,2-dioxygenase HGD 3081 NM_000187 /// XM_005247412 /// XM_005247413 /// XM_005247414 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004411 // homogentisate 1,2-dioxygenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 214309_s_at AI435747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI435747 /FEA=EST /DB_XREF=gi:4305347 /DB_XREF=est:th53f01.x1 /CLONE=IMAGE:2122009 /UG=Hs.153452 chromosome 21 open reading frame 2 AI435747 214310_s_at AI767884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767884 /FEA=EST /DB_XREF=gi:5234393 /DB_XREF=est:wi98g11.x1 /CLONE=IMAGE:2401412 /UG=Hs.155165 zinc finger protein-like 1 AI767884 zinc finger protein-like 1 ZFPL1 7542 NM_006782 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214311_at AI767884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI767884 /FEA=EST /DB_XREF=gi:5234393 /DB_XREF=est:wi98g11.x1 /CLONE=IMAGE:2401412 /UG=Hs.155165 zinc finger protein-like 1 AI767884 zinc finger protein-like 1 ZFPL1 7542 NM_006782 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214312_at AI693985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI693985 /FEA=EST /DB_XREF=gi:4971325 /DB_XREF=est:wd13d07.x1 /CLONE=IMAGE:2328013 /UG=Hs.155651 hepatocyte nuclear factor 3, beta AI693985 forkhead box A2 FOXA2 3170 NM_021784 /// NM_153675 /// XM_006723562 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0000433 // negative regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // not recorded /// 0001705 // ectoderm formation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010817 // regulation of hormone levels // not recorded /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0031018 // endocrine pancreas development // inferred from direct assay /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from sequence or structural similarity /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // not recorded /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // not recorded /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048665 // neuron fate specification // not recorded /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061448 // connective tissue development // inferred from electronic annotation /// 0070741 // response to interleukin-6 // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from sequence or structural similarity /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred by curator /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2000971 // negative regulation of detection of glucose // inferred from sequence or structural similarity /// 2000976 // regulation of transcription from RNA polymerase II promoter involved in detection of glucose // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 214313_s_at BE138647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE138647 /FEA=EST /DB_XREF=gi:8601147 /DB_XREF=est:xr78h03.x2 /CLONE=IMAGE:2766293 /UG=Hs.158688 KIAA0741 gene product BE138647 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214314_s_at BE138647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE138647 /FEA=EST /DB_XREF=gi:8601147 /DB_XREF=est:xr78h03.x2 /CLONE=IMAGE:2766293 /UG=Hs.158688 KIAA0741 gene product BE138647 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214315_x_at AI348935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348935 /FEA=EST /DB_XREF=gi:4086141 /DB_XREF=est:tb60a01.x1 /CLONE=IMAGE:2058696 /UG=Hs.16488 calreticulin AI348935 calreticulin CALR 811 NM_004343 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002502 // peptide antigen assembly with MHC class I protein complex // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from genetic interaction /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from genetic interaction /// 0045787 // positive regulation of cell cycle // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050821 // protein stabilization // traceable author statement /// 0051208 // sequestering of calcium ion // traceable author statement /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from genetic interaction /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005844 // polysome // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042824 // MHC class I peptide loading complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement /// 0071682 // endocytic vesicle lumen // traceable author statement 0001849 // complement component C1q binding // traceable author statement /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0030246 // carbohydrate binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement 214316_x_at AI378706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI378706 /FEA=EST /DB_XREF=gi:4188559 /DB_XREF=est:tb91f09.x1 /CLONE=IMAGE:2061737 /UG=Hs.16488 calreticulin AI378706 CTC-425F1.4 214317_x_at BE348997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE348997 /FEA=EST /DB_XREF=gi:9260850 /DB_XREF=est:ht47e11.x1 /CLONE=IMAGE:3149900 /UG=Hs.180920 ribosomal protein S9 BE348997 ribosomal protein S9 RPS9 6203 NM_001013 /// XM_005259135 /// XM_005259136 /// XM_005277084 /// XM_005277085 /// XM_005277274 /// XM_005277315 /// XM_005277316 /// XM_005278287 /// XM_005278288 /// XM_006725876 /// XM_006725877 /// XM_006725964 /// XM_006725965 /// XM_006726063 /// XM_006726064 /// XM_006726164 /// XM_006726165 /// XM_006726201 /// XM_006726202 /// XR_243946 /// XR_243947 /// XR_254260 /// XR_254311 /// XR_254323 /// XR_254324 /// XR_254517 /// XR_254518 /// XR_430207 /// XR_430911 /// XR_430953 /// XR_430986 /// XR_430987 /// XR_430988 /// XR_431006 /// XR_431007 /// XR_431008 /// XR_431025 /// XR_431026 /// XR_431027 /// XR_431056 /// XR_431057 /// XR_431058 /// XR_431067 /// XR_431068 /// XR_431069 /// XR_431090 /// XR_431099 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype 214318_s_at W58342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W58342 /FEA=EST /DB_XREF=gi:1365125 /DB_XREF=est:zd25a08.s1 /CLONE=IMAGE:341654 /UG=Hs.181304 putative gene product W58342 furry homolog (Drosophila) FRY 10129 NM_023037 /// XM_006719749 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 214319_at W58342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W58342 /FEA=EST /DB_XREF=gi:1365125 /DB_XREF=est:zd25a08.s1 /CLONE=IMAGE:341654 /UG=Hs.181304 putative gene product W58342 furry homolog (Drosophila) FRY 10129 NM_023037 /// XM_006719749 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 214320_x_at T67741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T67741 /FEA=EST /DB_XREF=gi:678889 /DB_XREF=est:yc27g09.s1 /CLONE=IMAGE:81952 /UG=Hs.183584 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 T67741 cytochrome P450, family 2, subfamily A, polypeptide 6 CYP2A6 1548 NM_000762 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214321_at BF440025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF440025 /FEA=EST /DB_XREF=gi:11452542 /DB_XREF=est:nac52c12.x1 /CLONE=IMAGE:3406079 /UG=Hs.235935 nephroblastoma overexpressed gene BF440025 nephroblastoma overexpressed NOV 4856 NM_002514 0001558 // regulation of cell growth // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 214322_at AA284757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284757 /FEA=EST /DB_XREF=gi:1927298 /DB_XREF=est:zt21h01.s1 /CLONE=IMAGE:713809 /UG=Hs.250857 calciumcalmodulin-dependent protein kinase (CaM kinase) II gamma AA284757 calcium/calmodulin-dependent protein kinase II gamma CAMK2G 818 NM_001204492 /// NM_001222 /// NM_172169 /// NM_172170 /// NM_172171 /// NM_172172 /// NM_172173 /// XM_005270195 /// XM_005270197 /// XM_005270198 /// XM_005270199 /// XM_005270200 /// XM_005270201 /// XM_005270202 /// XM_005270203 /// XM_005270205 /// XM_006717993 /// XM_006717994 /// XM_006717995 /// XM_006717996 /// XM_006717997 /// XM_006717998 /// XM_006717999 /// XM_006718000 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030073 // insulin secretion // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 1901897 // regulation of relaxation of cardiac muscle // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214323_s_at N36842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36842 /FEA=EST /DB_XREF=gi:1157984 /DB_XREF=est:yy35g03.s1 /CLONE=IMAGE:273268 /UG=Hs.274412 similar to yeast Upf3, variant A N36842 UPF3 regulator of nonsense transcripts homolog A (yeast) UPF3A 65110 NM_023011 /// NM_080687 /// XM_005266200 /// XM_005266201 /// XM_005266202 /// XM_006719991 /// XR_429283 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0035145 // exon-exon junction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214324_at BF222483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222483 /FEA=EST /DB_XREF=gi:11129660 /DB_XREF=est:7p53a01.x1 /CLONE=IMAGE:3649417 /UG=Hs.274454 ESTs, Weakly similar to 2004399A chromosomal protein H.sapiens BF222483 glycoprotein 2 (zymogen granule membrane) GP2 2813 NM_001007240 /// NM_001007241 /// NM_001007242 /// NM_001502 /// XM_005255259 /// XM_005255261 /// XR_429676 0002412 // antigen transcytosis by M cells in mucosal-associated lymphoid tissue // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003823 // antigen binding // inferred from electronic annotation 214325_at BF046750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF046750 /FEA=EST /DB_XREF=gi:10763806 /DB_XREF=est:INSSA4 /CLONE=227760 /UG=Hs.274454 ESTs, Weakly similar to 2004399A chromosomal protein H.sapiens BF046750 glycoprotein 2 (zymogen granule membrane) GP2 2813 NM_001007240 /// NM_001007241 /// NM_001007242 /// NM_001502 /// XM_005255259 /// XM_005255261 /// XR_429676 0002412 // antigen transcytosis by M cells in mucosal-associated lymphoid tissue // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003823 // antigen binding // inferred from electronic annotation 214326_x_at AI339541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI339541 /FEA=EST /DB_XREF=gi:4076468 /DB_XREF=est:qk62c02.x1 /CLONE=IMAGE:1873538 /UG=Hs.2780 jun D proto-oncogene AI339541 jun D proto-oncogene JUND 3727 NM_001286968 /// NM_005354 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 214327_x_at AI888178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI888178 /FEA=EST /DB_XREF=gi:5593342 /DB_XREF=est:wm40b09.x1 /CLONE=IMAGE:2438393 /UG=Hs.279860 tumor protein, translationally-controlled 1 AI888178 uncharacterized LOC101928826 /// tumor protein, translationally-controlled 1 LOC101928826 /// TPT1 7178 /// 101928826 NM_001286272 /// NM_001286273 /// NM_003295 /// XR_242670 /// XR_250536 /// XR_252641 0006816 // calcium ion transport // inferred by curator /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0009615 // response to virus // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000384 // negative regulation of ectoderm development // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005771 // multivesicular body // inferred from direct assay /// 0045298 // tubulin complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214328_s_at R01140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R01140 /FEA=EST /DB_XREF=gi:750876 /DB_XREF=est:ye88e02.s1 /CLONE=IMAGE:124826 /UG=Hs.289088 heat shock 90kD protein 1, alpha R01140 heat shock protein 90kDa alpha (cytosolic), class A member 1 HSP90AA1 3320 NM_001017963 /// NM_005348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042026 // protein refolding // traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0030911 // TPR domain binding // inferred from direct assay /// 0030911 // TPR domain binding // traceable author statement /// 0032564 // dATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 214329_x_at AW474434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW474434 /FEA=EST /DB_XREF=gi:7044540 /DB_XREF=est:xs95h07.x1 /CLONE=IMAGE:2777437 /UG=Hs.301527 ESTs, Moderately similar to unknown H.sapiens AW474434 tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 8743 NM_001190942 /// NM_001190943 /// NM_003810 /// NR_033994 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214330_at AF070584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070584.1 /DEF=Homo sapiens clone 24462 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387957 /UG=Hs.306254 Homo sapiens clone 24462 mRNA sequence AF070584 ATP synthase mitochondrial F1 complex assembly factor 2 ATPAF2 91647 NM_145691 /// XM_005256848 0043461 // proton-transporting ATP synthase complex assembly // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214331_at AI796813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796813 /FEA=EST /DB_XREF=gi:5362276 /DB_XREF=est:we22f06.x1 /CLONE=IMAGE:2341859 /UG=Hs.47344 advillin AI796813 Ts translation elongation factor, mitochondrial TSFM 10102 NM_001172695 /// NM_001172696 /// NM_001172697 /// NM_005726 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214332_s_at AI796813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI796813 /FEA=EST /DB_XREF=gi:5362276 /DB_XREF=est:we22f06.x1 /CLONE=IMAGE:2341859 /UG=Hs.47344 advillin AI796813 Ts translation elongation factor, mitochondrial TSFM 10102 NM_001172695 /// NM_001172696 /// NM_001172697 /// NM_005726 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214333_x_at U69268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U69268.1 /DEF=Human clone ID 193225 NAD (H)-specific isocitrate dehydrogenase gamma subunit mRNA, alternatively spliced, partial cds. /FEA=mRNA /PROD=NAD (H)-specific isocitrate dehydrogenase gammasubunit /DB_XREF=gi:2393762 /UG=Hs.75253 isocitrate dehydrogenase 3 (NAD+) gamma U69268 isocitrate dehydrogenase 3 (NAD+) gamma IDH3G 3421 NM_004135 /// NM_174869 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 214334_x_at N34846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N34846 /FEA=EST /DB_XREF=gi:1155988 /DB_XREF=est:yy45e11.s1 /CLONE=IMAGE:276524 /UG=Hs.75416 DAZ associated protein 2 N34846 DAZ associated protein 2 DAZAP2 9802 NM_001136264 /// NM_001136266 /// NM_001136267 /// NM_001136268 /// NM_001136269 /// NM_014764 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 214335_at AI669349 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI669349 /FEA=EST /DB_XREF=gi:4834123 /DB_XREF=est:ty31c07.x1 /CLONE=IMAGE:2280684 /UG=Hs.75458 ribosomal protein L18 AI669349 ribosomal protein L18 RPL18 6141 NM_000979 /// NM_001270490 /// NR_073022 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 214336_s_at AI621079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI621079 /FEA=EST /DB_XREF=gi:4630205 /DB_XREF=est:ts76f11.x1 /CLONE=IMAGE:2237229 /UG=Hs.75887 coatomer protein complex, subunit alpha AI621079 coatomer protein complex, subunit alpha COPA 1314 NM_001098398 /// NM_004371 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030157 // pancreatic juice secretion // inferred from direct assay /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214337_at AI621079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI621079 /FEA=EST /DB_XREF=gi:4630205 /DB_XREF=est:ts76f11.x1 /CLONE=IMAGE:2237229 /UG=Hs.75887 coatomer protein complex, subunit alpha AI621079 coatomer protein complex, subunit alpha COPA 1314 NM_001098398 /// NM_004371 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030157 // pancreatic juice secretion // inferred from direct assay /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation 214338_at AL050381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050381.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B2023 (from clone DKFZp586B2023). /FEA=mRNA /DB_XREF=gi:4914611 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 AL050381 DnaJ (Hsp40) homolog, subfamily B, member 12 DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214339_s_at AA744529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA744529 /FEA=EST /DB_XREF=gi:2783293 /DB_XREF=est:ny79a04.s1 /CLONE=IMAGE:1284462 /UG=Hs.86575 mitogen-activated protein kinase kinase kinase kinase 1 AA744529 mitogen-activated protein kinase kinase kinase kinase 1 MAP4K1 11184 NM_001042600 /// NM_007181 /// XM_006722993 0000185 // activation of MAPKKK activity // inferred by curator /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214340_at AF020774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF020774.1 /DEF=Homo sapiens hair and skin epidermal-type 12-lipoxygenase-related protein (ALOX12E) mRNA, complete pseudogene sequence. /FEA=mRNA /GEN=ALOX12E /DB_XREF=gi:2582378 /UG=Hs.88844 Homo sapiens hair and skin epidermal-type 12-lipoxygenase-related protein (ALOX12E) mRNA, complete pseudogene sequence AF020774 arachidonate 12-lipoxygenase pseudogene 2 ALOX12P2 245 NR_002710 /// NR_120453 214341_at AI741833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI741833 /FEA=EST /DB_XREF=gi:5110121 /DB_XREF=est:wg29e04.x1 /CLONE=IMAGE:2366526 /UG=Hs.8991 adaptor-related protein complex 1, gamma 2 subunit AI741833 adaptor-related protein complex 1, gamma 2 subunit AP1G2 8906 NM_001282474 /// NM_001282475 /// NM_003917 /// NM_080545 /// XM_005268166 /// XM_005268167 /// XM_005268168 /// XM_005268169 /// XM_005268170 /// XM_005268171 /// XM_005268172 /// XM_005268173 /// XM_005268174 /// XM_005268175 /// XM_005268176 /// XM_005268177 /// XM_005268178 /// XM_005268179 /// XM_005268180 /// XM_005268181 /// XM_005268182 /// XM_006720301 /// XR_245729 /// XR_245730 0006091 // generation of precursor metabolites and energy // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006772 // thiamine metabolic process // traceable author statement /// 0006772 // thiamine metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0042357 // thiamine diphosphate metabolic process // inferred from sequence or structural similarity /// 0042723 // thiamine-containing compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050333 // thiamin-triphosphatase activity // inferred from direct assay /// 0050333 // thiamin-triphosphatase activity // traceable author statement /// 0050333 // thiamin-triphosphatase activity // inferred from electronic annotation 214342_at AI017382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI017382 /FEA=EST /DB_XREF=gi:3231718 /DB_XREF=est:ou92e06.x1 /CLONE=IMAGE:1635298 /UG=Hs.114012 KIAA1218 protein AI017382 ataxin 7-like 1 ATXN7L1 222255 NM_020725 /// NM_138495 /// NM_152749 /// XM_005250219 /// XM_005250220 /// XM_005250221 /// XM_006715900 /// XM_006715901 /// XM_006715902 /// XM_006715903 /// XM_006715904 /// XR_242226 214343_s_at AI017382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI017382 /FEA=EST /DB_XREF=gi:3231718 /DB_XREF=est:ou92e06.x1 /CLONE=IMAGE:1635298 /UG=Hs.114012 KIAA1218 protein AI017382 ataxin 7-like 1 ATXN7L1 222255 NM_020725 /// NM_138495 /// NM_152749 /// XM_005250219 /// XM_005250220 /// XM_005250221 /// XM_006715900 /// XM_006715901 /// XM_006715902 /// XM_006715903 /// XM_006715904 /// XR_242226 214344_at R87507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R87507 /FEA=EST /DB_XREF=gi:946320 /DB_XREF=est:ym91b06.s1 /CLONE=IMAGE:166259 /UG=Hs.12509 Homo sapiens clone 23583 mRNA sequence R87507 long intergenic non-protein coding RNA 950 LINC00950 92973 NR_024006 214345_at BF058643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF058643 /FEA=EST /DB_XREF=gi:10812539 /DB_XREF=est:7k33b06.x1 /CLONE=IMAGE:3477082 /UG=Hs.129764 EGF-like repeats and discoidin I-like domains 3 BF058643 CTD-2269F5.1 214346_at AW026646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW026646 /FEA=EST /DB_XREF=gi:5880099 /DB_XREF=est:wv15b05.x1 /CLONE=IMAGE:2529585 /UG=Hs.134012 C1q-related factor AW026646 complement component 1, q subcomponent-like 1 C1QL1 10882 NM_006688 0007626 // locomotory behavior // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 214347_s_at AW772056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW772056 /FEA=EST /DB_XREF=gi:7704118 /DB_XREF=est:hn64g06.x1 /CLONE=IMAGE:3032698 /UG=Hs.150403 dopa decarboxylase (aromatic L-amino acid decarboxylase) AW772056 dopa decarboxylase (aromatic L-amino acid decarboxylase) DDC 1644 NM_000790 /// NM_001082971 /// NM_001242886 /// NM_001242887 /// NM_001242888 /// NM_001242889 /// NM_001242890 /// XM_005271745 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015842 // synaptic vesicle amine transport // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0033076 // isoquinoline alkaloid metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042423 // catecholamine biosynthetic process // traceable author statement /// 0042427 // serotonin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 0046684 // response to pyrethroid // inferred from electronic annotation /// 0052314 // phytoalexin metabolic process // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004058 // aromatic-L-amino-acid decarboxylase activity // inferred from direct assay /// 0004058 // aromatic-L-amino-acid decarboxylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 214348_at NM_001057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001057.1 /DEF=Homo sapiens tachykinin receptor 2 (TACR2), mRNA. /FEA=CDS /GEN=TACR2 /PROD=tachykinin receptor 2 /DB_XREF=gi:4507344 /UG=Hs.161305 tachykinin receptor 2 /FL=gb:M57414.1 gb:NM_001057.1 NM_001057 tachykinin receptor 2 TACR2 6865 NM_001057 0006936 // muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007217 // tachykinin receptor signaling pathway // traceable author statement /// 0007588 // excretion // traceable author statement /// 0014057 // positive regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0014827 // intestine smooth muscle contraction // inferred from electronic annotation /// 0033685 // negative regulation of luteinizing hormone secretion // inferred from electronic annotation /// 0035106 // operant conditioning // inferred from electronic annotation /// 0043117 // positive regulation of vascular permeability // inferred from electronic annotation /// 0043270 // positive regulation of ion transport // inferred from electronic annotation /// 0070459 // prolactin secretion // inferred from electronic annotation /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004995 // tachykinin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016497 // substance K receptor activity // inferred from electronic annotation 214349_at AV764378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV764378 /FEA=EST /DB_XREF=gi:10922226 /DB_XREF=est:AV764378 /CLONE=MDSAOE03 /UG=Hs.163863 ESTs, Moderately similar to POL2_HUMAN RETROVIRUS-RELATED POL POLYPROTEIN H.sapiens AV764378 214350_at AI762021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762021 /FEA=EST /DB_XREF=gi:5177688 /DB_XREF=est:wh89f01.x1 /CLONE=IMAGE:2387929 /UG=Hs.172278 syntrophin, beta 2 (dystrophin-associated protein A1, 59kD, basic component 2) AI762021 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) SNTB2 6645 NM_006750 /// NM_130845 /// XM_005256120 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214351_x_at AA789278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA789278 /FEA=EST /DB_XREF=gi:2849398 /DB_XREF=est:aj28b10.s1 /CLONE=1391611 /UG=Hs.180842 ribosomal protein L13 AA789278 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214352_s_at BF673699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF673699 /FEA=EST /DB_XREF=gi:11947594 /DB_XREF=est:602136427F1 /CLONE=IMAGE:4272774 /UG=Hs.184050 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog BF673699 Kirsten rat sarcoma viral oncogene homolog KRAS 3845 NM_004985 /// NM_033360 /// XM_006719069 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 214353_at AW241864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW241864 /FEA=EST /DB_XREF=gi:6575618 /DB_XREF=est:xn76b12.x1 /CLONE=IMAGE:2700383 /UG=Hs.252387 cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog AW241864 214354_x_at T91506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T91506 /FEA=EST /DB_XREF=gi:723419 /DB_XREF=est:ye20c02.s1 /CLONE=IMAGE:118274 /UG=Hs.264330 N-acylsphingosine amidohydrolase (acid ceramidase)-like T91506 surfactant protein B SFTPB 6439 NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation 214355_x_at AW274747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW274747 /FEA=EST /DB_XREF=gi:6661777 /DB_XREF=est:xn34e08.x1 /CLONE=IMAGE:2695622 /UG=Hs.270527 Homo sapiens mRNA; cDNA DKFZp434F0327 (from clone DKFZp434F0327) AW274747 CTAGE family, member 15 /// CTAGE family, member 4 /// CTAGE family, member 8 /// CTAGE family, member 9 CTAGE15 /// CTAGE4 /// CTAGE8 /// CTAGE9 441294 /// 643854 /// 100128553 /// 100142659 NM_001008747 /// NM_001145659 /// NM_001278507 /// NM_198495 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation 214356_s_at AI272899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI272899 /FEA=EST /DB_XREF=gi:3895167 /DB_XREF=est:ql47c07.x1 /CLONE=IMAGE:1875468 /UG=Hs.3852 KIAA0368 protein AI272899 KIAA0368 KIAA0368 23392 NM_001080398 /// XM_005251850 /// XM_005251851 /// XM_005251852 /// XM_005251853 /// XM_005251854 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 214357_at AL035295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035295.1 /DEF=H.sapiens gene from PAC 106H8, similar to Dynamin. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4200217 /UG=Hs.56175 H.sapiens gene from PAC 106H8, similar to Dynamin AL035295 chromosome 1 open reading frame 105 C1orf105 92346 NM_139240 /// XM_005245608 /// XM_005245609 /// XM_005245610 /// XM_006711630 214358_at AW188201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188201 /FEA=EST /DB_XREF=gi:6462637 /DB_XREF=est:xj93f06.x1 /CLONE=IMAGE:2664803 /UG=Hs.7232 acetyl-Coenzyme A carboxylase alpha AW188201 acetyl-CoA carboxylase alpha ACACA 31 NM_000664 /// NM_198834 /// NM_198835 /// NM_198836 /// NM_198837 /// NM_198838 /// NM_198839 /// XM_005257266 /// XM_005257267 /// XM_005257268 /// XM_006721853 /// XM_006725320 /// XM_006725321 /// XM_006725322 /// XR_424818 /// XR_429952 /// XR_430795 /// XR_433374 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006084 // acetyl-CoA metabolic process // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044268 // multicellular organismal protein metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from sequence or structural similarity /// 0003989 // acetyl-CoA carboxylase activity // traceable author statement /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214359_s_at AI218219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI218219 /FEA=EST /DB_XREF=gi:3798034 /DB_XREF=est:qh17h11.x1 /CLONE=IMAGE:1844997 /UG=Hs.74335 heat shock 90kD protein 1, beta AI218219 heat shock protein 90kDa alpha (cytosolic), class B member 1 HSP90AB1 3326 NM_001271969 /// NM_001271970 /// NM_001271971 /// NM_001271972 /// NM_007355 /// NR_073528 /// XM_005249075 0001890 // placenta development // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009651 // response to salt stress // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // inferred from mutant phenotype /// 0060338 // regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from sequence or structural similarity /// 0030911 // TPR domain binding // inferred from sequence or structural similarity /// 0032564 // dATP binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 214360_at AA772023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA772023 /FEA=EST /DB_XREF=gi:2823806 /DB_XREF=est:ai39f04.s1 /CLONE=1359391 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AA772023 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 214361_s_at AW170602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW170602 /FEA=EST /DB_XREF=gi:6402127 /DB_XREF=est:xn64e03.x1 /CLONE=IMAGE:2698492 /UG=Hs.78281 regulator of G-protein signalling 12 AW170602 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from direct assay 214362_at AW170602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW170602 /FEA=EST /DB_XREF=gi:6402127 /DB_XREF=est:xn64e03.x1 /CLONE=IMAGE:2698492 /UG=Hs.78281 regulator of G-protein signalling 12 AW170602 regulator of G-protein signaling 12 RGS12 6002 NM_002926 /// NM_198227 /// NM_198229 /// NM_198230 /// NM_198430 /// NM_198432 /// NM_198587 /// XM_006713905 /// XM_006713906 /// XM_006713907 /// XR_427479 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016363 // nuclear matrix // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0030695 // GTPase regulator activity // inferred from direct assay 214363_s_at AA129420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129420 /FEA=EST /DB_XREF=gi:1689185 /DB_XREF=est:zn85c07.s1 /CLONE=IMAGE:564972 /UG=Hs.78825 matrin 3 AA129420 matrin 3 /// small nucleolar RNA host gene 4 (non-protein coding) MATR3 /// SNHG4 9782 /// 724102 NM_001194954 /// NM_001194955 /// NM_001194956 /// NM_001282278 /// NM_018834 /// NM_199189 /// NR_003141 /// NR_036536 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214364_at W84525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W84525 /FEA=EST /DB_XREF=gi:1395637 /DB_XREF=est:zd90g09.s1 /CLONE=IMAGE:356800 /UG=Hs.7949 DKFZP586B2420 protein W84525 mitochondrial transcription termination factor 4 MTERF4 130916 NM_182501 /// NR_028049 /// NR_028050 /// NR_028051 /// XM_006712289 /// XM_006712290 /// XM_006712291 /// XM_006712292 /// XM_006712293 /// XM_006712294 /// XM_006712295 0006364 // rRNA processing // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from direct assay 214365_at X04201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X04201.1 /DEF=Human skeletal muscle 1.3 kb mRNA for tropomyosin. /FEA=mRNA /DB_XREF=gi:37429 /UG=Hs.85844 neurotrophic tyrosine kinase, receptor, type 1 X04201 tropomyosin 3 TPM3 7170 NM_001043351 /// NM_001043352 /// NM_001043353 /// NM_001278188 /// NM_001278189 /// NM_001278190 /// NM_001278191 /// NM_152263 /// NM_153649 /// NR_103460 /// NR_103461 /// XM_006711515 /// XM_006711516 /// XM_006711517 /// XM_006711518 /// XM_006711519 /// XM_006711520 /// XM_006711521 /// XM_006711522 /// XM_006711523 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005862 // muscle thin filament tropomyosin // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 214366_s_at AA995910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA995910 /FEA=EST /DB_XREF=gi:3182399 /DB_XREF=est:ou44g05.s1 /CLONE=IMAGE:1629176 /UG=Hs.89499 arachidonate 5-lipoxygenase AA995910 arachidonate 5-lipoxygenase ALOX5 240 NM_000698 /// NM_001256153 /// NM_001256154 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0004051 // arachidonate 5-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 214367_at AI688812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688812 /FEA=EST /DB_XREF=gi:4900106 /DB_XREF=est:wd41c03.x1 /CLONE=IMAGE:2330692 /UG=Hs.99491 RAS guanyl releasing protein 2 (calcium and DAG-regulated) AI688812 RAS guanyl releasing protein 2 (calcium and DAG-regulated) RASGRP2 10235 NM_001098670 /// NM_001098671 /// NM_005825 /// NM_153819 /// XM_005273707 /// XM_006718411 /// XM_006718412 /// XM_006718413 /// XM_006718414 /// XM_006718415 /// XM_006718416 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0008289 // lipid binding // traceable author statement /// 0019992 // diacylglycerol binding // non-traceable author statement 214368_at AI688812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688812 /FEA=EST /DB_XREF=gi:4900106 /DB_XREF=est:wd41c03.x1 /CLONE=IMAGE:2330692 /UG=Hs.99491 RAS guanyl releasing protein 2 (calcium and DAG-regulated) AI688812 RAS guanyl releasing protein 2 (calcium and DAG-regulated) RASGRP2 10235 NM_001098670 /// NM_001098671 /// NM_005825 /// NM_153819 /// XM_005273707 /// XM_006718411 /// XM_006718412 /// XM_006718413 /// XM_006718414 /// XM_006718415 /// XM_006718416 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0008289 // lipid binding // traceable author statement /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214369_s_at AI688812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688812 /FEA=EST /DB_XREF=gi:4900106 /DB_XREF=est:wd41c03.x1 /CLONE=IMAGE:2330692 /UG=Hs.99491 RAS guanyl releasing protein 2 (calcium and DAG-regulated) AI688812 RAS guanyl releasing protein 2 (calcium and DAG-regulated) RASGRP2 10235 NM_001098670 /// NM_001098671 /// NM_005825 /// NM_153819 /// XM_005273707 /// XM_006718411 /// XM_006718412 /// XM_006718413 /// XM_006718414 /// XM_006718415 /// XM_006718416 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0008289 // lipid binding // traceable author statement /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214370_at AW238654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW238654 /FEA=EST /DB_XREF=gi:6571043 /DB_XREF=est:xp29f06.x1 /CLONE=IMAGE:2741795 /UG=Hs.100000 S100 calcium-binding protein A8 (calgranulin A) AW238654 S100 calcium binding protein A8 S100A8 6279 NM_002964 0001816 // cytokine production // traceable author statement /// 0002523 // leukocyte migration involved in inflammatory response // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006914 // autophagy // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0032119 // sequestering of zinc ion // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032602 // chemokine production // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0070488 // neutrophil aggregation // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0035662 // Toll-like receptor 4 binding // traceable author statement /// 0050544 // arachidonic acid binding // traceable author statement /// 0050786 // RAGE receptor binding // traceable author statement 214371_at AI652441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652441 /FEA=EST /DB_XREF=gi:4736420 /DB_XREF=est:wb29b08.x1 /CLONE=IMAGE:2307063 /UG=Hs.103978 serinethreonine kinase 22B (spermiogenesis associated) AI652441 testis-specific serine kinase 2 TSSK2 23617 NM_053006 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214372_x_at AI732416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732416 /FEA=EST /DB_XREF=gi:5053529 /DB_XREF=est:zl91b12.x5 /CLONE=IMAGE:511967 /UG=Hs.114905 IRE1, S. cerevisiae, homolog of AI732416 endoplasmic reticulum to nucleus signaling 2 ERN2 10595 NM_033266 /// XM_005255044 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016075 // rRNA catabolic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from direct assay /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214373_at AI582773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI582773 /FEA=EST /DB_XREF=gi:4568670 /DB_XREF=est:tn17d08.x1 /CLONE=IMAGE:2167887 /UG=Hs.125682 protein phosphatase 4 regulatory subunit 2 AI582773 214374_s_at AI962377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962377 /FEA=EST /DB_XREF=gi:5755090 /DB_XREF=est:wq51g07.x1 /CLONE=IMAGE:2474844 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) AI962377 PTPRF interacting protein, binding protein 1 (liprin beta 1) PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0000187 // activation of MAPK activity // traceable author statement /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0048666 // neuron development // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214375_at AI962377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962377 /FEA=EST /DB_XREF=gi:5755090 /DB_XREF=est:wq51g07.x1 /CLONE=IMAGE:2474844 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) AI962377 PTPRF interacting protein, binding protein 1 (liprin beta 1) PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0007155 // cell adhesion // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 214376_at AI263044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI263044 /FEA=EST /DB_XREF=gi:3871247 /DB_XREF=est:qz29e03.x1 /CLONE=IMAGE:2028316 /UG=Hs.13438 Homo sapiens clone 24626 mRNA sequence AI263044 mitogen-activated protein kinase 10 MAPK10 5602 NM_002753 /// NM_138980 /// NM_138981 /// NM_138982 /// XM_005263129 /// XM_005263130 /// XM_005263131 /// XM_005263135 /// XM_005263136 /// XM_005263138 /// XM_006714267 /// XM_006714268 /// XM_006714269 /// XM_006714270 /// XM_006714271 /// XM_006714272 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from sequence or structural similarity /// 0007258 // JUN phosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004705 // JUN kinase activity // inferred from sequence or structural similarity /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214377_s_at BF508685 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508685 /FEA=EST /DB_XREF=gi:11591983 /DB_XREF=est:UI-H-BI4-aop-e-12-0-UI.s1 /CLONE=IMAGE:3085559 /UG=Hs.150601 chymotrypsin-like BF508685 chymotrypsin-like CTRL 1506 NM_001907 0006508 // proteolysis // inferred from electronic annotation /// 0007586 // digestion // traceable author statement 0005615 // extracellular space // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214378_at BF109662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF109662 /FEA=EST /DB_XREF=gi:10939352 /DB_XREF=est:7l66e04.x1 /CLONE=IMAGE:3526374 /UG=Hs.170279 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) BF109662 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 7035 NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 214379_at AI954458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI954458 /FEA=EST /DB_XREF=gi:5746768 /DB_XREF=est:wr49f12.x1 /CLONE=IMAGE:2491055 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like AI954458 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 214380_at AI334332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI334332 /FEA=EST /DB_XREF=gi:4070891 /DB_XREF=est:qq31b04.x1 /CLONE=IMAGE:1934095 /UG=Hs.183438 DKFZP566J153 protein AI334332 pre-mRNA processing factor 31 PRPF31 26121 NM_015629 /// XM_005258729 /// XM_005277071 /// XM_005277249 /// XM_005278258 /// XM_006723137 /// XM_006725641 /// XM_006725767 /// XM_006725768 /// XM_006725868 /// XM_006725869 /// XM_006725956 /// XM_006725957 /// XM_006726055 /// XM_006726056 /// XM_006726153 /// XM_006726154 /// XM_006726193 /// XM_006726194 /// XM_006726273 /// XM_006726309 0000244 // spliceosomal tri-snRNP complex assembly // inferred from direct assay /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005684 // U2-type spliceosomal complex // inferred by curator /// 0005687 // U4 snRNP // inferred from direct assay /// 0005690 // U4atac snRNP // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070990 // snRNP binding // inferred from physical interaction 214381_at BG150564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG150564 /FEA=EST /DB_XREF=gi:12662594 /DB_XREF=est:7k02g04.x1 /CLONE=IMAGE:3443143 /UG=Hs.184326 CDC10 (cell division cycle 10, S. cerevisiae, homolog) BG150564 septin 7 pseudogene LOC441601 441601 NR_003034 214382_at AL021331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021331 /DEF=Human DNA sequence from clone 366N23 on chromosome 6q27. Contains two genes similar to consecutive parts of the C. elegans UNC-93 (protein 1, C46F11.1) gene, a KIAA0173 and Tubulin-Tyrosine Ligase LIKE gene, a Mitotic Feedback Control Protein MADP... /FEA=mRNA_2 /DB_XREF=gi:3355532 /UG=Hs.22033 Human DNA sequence from clone 366N23 on chromosome 6q27. Contains two genes similar to consecutive parts of the C. elegans UNC-93 (protein 1, C46F11.1) gene, a KIAA0173 and Tubulin-Tyrosine Ligase LIKE gene, a Mitotic Feedback Control Protein MADP2 Homolo AL021331 unc-93 homolog A (C. elegans) UNC93A 54346 NM_001143947 /// NM_018974 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 214383_x_at BF063121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF063121 /FEA=EST /DB_XREF=gi:10822031 /DB_XREF=est:7h83f11.x1 /CLONE=IMAGE:3322605 /UG=Hs.281706 sortilin 1 BF063121 kelch domain containing 3 KLHDC3 116138 NM_001242872 /// NM_057161 /// NR_040101 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // non-traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214384_s_at BF446672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF446672 /FEA=EST /DB_XREF=gi:11511810 /DB_XREF=est:7q90e08.x1 /CLONE=IMAGE:3705687 /UG=Hs.84153 dynactin 2 (p50) BF446672 dynactin 2 (p50) DCTN2 10540 NM_001261412 /// NM_001261413 /// NM_006400 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 214385_s_at AI521646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI521646 /FEA=EST /DB_XREF=gi:4435781 /DB_XREF=est:to66a06.x1 /CLONE=IMAGE:2183218 /UG=Hs.102482 mucin 5, subtype B, tracheobronchial AI521646 mucin 5AC, oligomeric mucus/gel-forming MUC5AC 4586 NM_017511 /// XM_006709945 /// XM_006709947 /// XM_006718399 /// XM_006726526 /// XM_006726528 0016266 // O-glycan processing // traceable author statement /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043205 // fibril // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement 214386_at AI939402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI939402 /FEA=EST /DB_XREF=gi:5678272 /DB_XREF=est:qi61g07.x5 /CLONE=IMAGE:1861020 /UG=Hs.104134 homeo box (H6 family) 1 AI939402 214387_x_at AA633841 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA633841 /FEA=EST /DB_XREF=gi:2557055 /DB_XREF=est:ac72g03.s1 /CLONE=IMAGE:868180 /UG=Hs.1074 surfactant, pulmonary-associated protein C AA633841 surfactant protein C SFTPC 6440 NM_001172357 /// NM_001172410 /// NM_003018 /// XM_005273598 /// XM_006716379 /// XM_006716380 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070741 // response to interleukin-6 // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071732 // cellular response to nitric oxide // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 214388_at AI732885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732885 /FEA=EST /DB_XREF=gi:5053998 /DB_XREF=est:oe64d04.x5 /CLONE=IMAGE:1416391 /UG=Hs.142907 Human BRCA2 region, mRNA sequence CG011 AI732885 214389_at AI733515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI733515 /FEA=EST /DB_XREF=gi:5054676 /DB_XREF=est:ou99e05.x5 /CLONE=IMAGE:1635968 /UG=Hs.148907 Homo sapiens mRNA; cDNA DKFZp564G223 (from clone DKFZp564G223) AI733515 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 SLC5A12 159963 NM_178498 /// XM_006718155 /// XM_006718156 /// XM_006718157 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 214390_s_at AI652662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI652662 /FEA=EST /DB_XREF=gi:4736641 /DB_XREF=est:wb30c12.x1 /CLONE=IMAGE:2307190 /UG=Hs.157205 branched chain aminotransferase 1, cytosolic AI652662 branched chain amino-acid transaminase 1, cytosolic BCAT1 586 NM_001178091 /// NM_001178092 /// NM_001178093 /// NM_001178094 /// NM_005504 /// XM_005253460 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation 214391_x_at AI762344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762344 /FEA=EST /DB_XREF=gi:5178011 /DB_XREF=est:wg97c05.x1 /CLONE=IMAGE:2379176 /UG=Hs.159360 prostaglandin E receptor 1 (subtype EP1), 42kD AI762344 prostaglandin E receptor 1 (subtype EP1), 42kDa PTGER1 5731 NM_000955 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004955 // prostaglandin receptor activity // inferred from electronic annotation /// 0004957 // prostaglandin E receptor activity // inferred from electronic annotation 214392_at AA431984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA431984 /FEA=EST /DB_XREF=gi:2115692 /DB_XREF=est:zw77c11.s1 /CLONE=IMAGE:782228 /UG=Hs.180943 hypothetical protein R30953_1 /FL=gb:NM_019612.1 AA431984 immunity-related GTPase family, cinema IRGC 56269 NM_019612 /// XM_005259058 /// XM_006723283 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 214393_at AI884814 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI884814 /FEA=EST /DB_XREF=gi:5589978 /DB_XREF=est:wl85a05.x1 /CLONE=IMAGE:2431664 /UG=Hs.21964 ESTs AI884814 Rho family GTPase 2 RND2 8153 NM_005440 /// XM_005257706 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0048672 // positive regulation of collateral sprouting // inferred from electronic annotation 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 214394_x_at AI613383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI613383 /FEA=EST /DB_XREF=gi:4622550 /DB_XREF=est:tt80e08.x1 /CLONE=IMAGE:2247110 /UG=Hs.223241 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) AI613383 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) EEF1D 1936 NM_001130053 /// NM_001130054 /// NM_001130055 /// NM_001130056 /// NM_001130057 /// NM_001195203 /// NM_001289950 /// NM_001960 /// NM_032378 /// XM_005250820 /// XM_005250821 /// XM_005250823 /// XM_005250824 /// XM_005250825 /// XM_005250826 /// XM_006716519 /// XM_006716520 /// XM_006716521 /// XM_006716522 /// XM_006716523 /// XM_006716524 /// XM_006716525 /// XM_006725064 /// XM_006725065 /// XM_006725066 /// XM_006725067 /// XM_006725068 /// XM_006725069 /// XM_006725070 /// XM_006725071 /// XM_006725072 /// XM_006725073 /// XM_006725074 /// XM_006725075 /// XM_006725076 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 214395_x_at AI335509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI335509 /FEA=EST /DB_XREF=gi:4072436 /DB_XREF=est:tb66h02.x1 /CLONE=IMAGE:2059347 /UG=Hs.223241 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) AI335509 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) EEF1D 1936 NM_001130053 /// NM_001130054 /// NM_001130055 /// NM_001130056 /// NM_001130057 /// NM_001195203 /// NM_001289950 /// NM_001960 /// NM_032378 /// XM_005250820 /// XM_005250821 /// XM_005250823 /// XM_005250824 /// XM_005250825 /// XM_005250826 /// XM_006716519 /// XM_006716520 /// XM_006716521 /// XM_006716522 /// XM_006716523 /// XM_006716524 /// XM_006716525 /// XM_006725064 /// XM_006725065 /// XM_006725066 /// XM_006725067 /// XM_006725068 /// XM_006725069 /// XM_006725070 /// XM_006725071 /// XM_006725072 /// XM_006725073 /// XM_006725074 /// XM_006725075 /// XM_006725076 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 214396_s_at AI827820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI827820 /FEA=EST /DB_XREF=gi:5448491 /DB_XREF=est:wf33f05.x1 /CLONE=IMAGE:2357409 /UG=Hs.25674 methyl-CpG binding domain protein 2 AI827820 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 214397_at AI827820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI827820 /FEA=EST /DB_XREF=gi:5448491 /DB_XREF=est:wf33f05.x1 /CLONE=IMAGE:2357409 /UG=Hs.25674 methyl-CpG binding domain protein 2 AI827820 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 214398_s_at AW340333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW340333 /FEA=EST /DB_XREF=gi:6836959 /DB_XREF=est:hd03e01.x1 /CLONE=IMAGE:2908440 /UG=Hs.321045 IKK-related kinase epsilon; inducible IkappaB kinase AW340333 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon IKBKE 9641 NM_001193321 /// NM_001193322 /// NM_014002 /// XM_005273356 /// XM_006711641 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004704 // NF-kappaB-inducing kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008384 // IkappaB kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214399_s_at BF588953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF588953 /FEA=EST /DB_XREF=gi:11681277 /DB_XREF=est:7i48c02.x1 /CLONE=IMAGE:3337922 /UG=Hs.3235 keratin 4 BF588953 keratin 4 KRT4 3851 NM_002272 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214400_at AI991694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991694 /FEA=EST /DB_XREF=gi:5838522 /DB_XREF=est:ws18d12.x1 /CLONE=IMAGE:2497559 /UG=Hs.37062 insulin-like 3 (Leydig cell) AI991694 insulin-like 3 (Leydig cell) INSL3 3640 NM_001265587 /// NM_005543 0001556 // oocyte maturation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0005102 // receptor binding // traceable author statement /// 0005158 // insulin receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 214401_at AA725078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA725078 /FEA=EST /DB_XREF=gi:2742785 /DB_XREF=est:ai08e12.s1 /CLONE=1342222 /UG=Hs.54567 paired box gene 1 /FL=gb:NM_006192.1 AA725078 paired box 1 PAX1 5075 NM_001257096 /// NM_006192 0001501 // skeletal system development // traceable author statement /// 0001756 // somitogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0043367 // CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0060017 // parathyroid gland development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0061056 // sclerotome development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 214402_s_at AA521233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521233 /FEA=EST /DB_XREF=gi:2261776 /DB_XREF=est:aa79a12.s1 /CLONE=IMAGE:827134 /UG=Hs.62209 KIAA0542 gene product AA521233 Sfi1 homolog, spindle assembly associated (yeast) SFI1 9814 NM_001007467 /// NM_001258325 /// NM_001258326 /// NM_001258327 /// NM_014775 /// XM_005261868 /// XM_005261869 /// XM_005261870 /// XM_005261871 /// XM_005261872 /// XM_005261873 /// XM_005261874 /// XM_006724388 /// XM_006724389 /// XM_006724390 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 214403_x_at AI307915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI307915 /FEA=EST /DB_XREF=gi:4002550 /DB_XREF=est:tb39c07.x1 /CLONE=IMAGE:2056716 /UG=Hs.79414 prostate epithelium-specific Ets transcription factor AI307915 SAM pointed domain containing ETS transcription factor SPDEF 25803 NM_001252294 /// NM_012391 /// XM_005248988 /// XM_006715048 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010455 // positive regulation of cell fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214404_x_at AI435670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI435670 /FEA=EST /DB_XREF=gi:4304809 /DB_XREF=est:th53b09.x1 /CLONE=IMAGE:2121977 /UG=Hs.79414 prostate epithelium-specific Ets transcription factor AI435670 SAM pointed domain containing ETS transcription factor SPDEF 25803 NM_001252294 /// NM_012391 /// XM_005248988 /// XM_006715048 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010455 // positive regulation of cell fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214405_at Z39557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z39557 /FEA=EST /DB_XREF=gi:562749 /DB_XREF=est:HSC1DB062 /CLONE=c-1db06 /UG=Hs.12533 Homo sapiens clone 23705 mRNA sequence Z39557 214406_s_at AW135332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW135332 /FEA=EST /DB_XREF=gi:6139465 /DB_XREF=est:UI-H-BI1-acb-h-12-0-UI.s1 /CLONE=IMAGE:2713967 /UG=Hs.197116 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 AW135332 solute carrier family 7, member 4 SLC7A4 6545 NM_004173 /// XM_005261716 /// XM_005261717 /// XM_006724309 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015802 // basic amino acid transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015174 // basic amino acid transmembrane transporter activity // traceable author statement 214407_x_at AI240545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI240545 /FEA=EST /DB_XREF=gi:3835942 /DB_XREF=est:qh52b08.x1 /CLONE=IMAGE:1848279 /UG=Hs.250653 glycophorin B (includes Ss blood group) AI240545 glycophorin B (MNS blood group) GYPB 2994 NM_002100 /// XM_005262968 /// XM_005262969 /// XM_005262970 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 214408_s_at AL021937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021937 /DEF=Human DNA sequence from clone RP1-149A16 on chromosome 22 Contains an IGLC (Immunoglobulin Lambda Chain C) pseudogene, the RFPL3 gene for Ret finger protein-like 3, the RFPL3S gene for Ret finger protein-like 3 antisense, the gene for a novel Immu... /FEA=mRNA_3 /DB_XREF=gi:4165210 /UG=Hs.274285 ret finger protein-like 3 antisense AL021937 RFPL1 antisense RNA 1 /// RFPL3 antisense RFPL1S /// RFPL3S 10737 /// 10740 NR_001450 /// NR_002596 /// NR_002727 /// NR_104232 214409_at AL021937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021937 /DEF=Human DNA sequence from clone RP1-149A16 on chromosome 22 Contains an IGLC (Immunoglobulin Lambda Chain C) pseudogene, the RFPL3 gene for Ret finger protein-like 3, the RFPL3S gene for Ret finger protein-like 3 antisense, the gene for a novel Immu... /FEA=mRNA_3 /DB_XREF=gi:4165210 /UG=Hs.274285 ret finger protein-like 3 antisense AL021937 RFPL3 antisense RFPL3S 10737 NR_001450 /// NR_002596 /// NR_104232 214410_at N32151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32151 /FEA=EST /DB_XREF=gi:1152550 /DB_XREF=est:yy23a12.s1 /CLONE=IMAGE:272062 /UG=Hs.43265 melastatin 1 N32151 RP11-348B17.1 214411_x_at AW584011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW584011 /FEA=EST /DB_XREF=gi:7260985 /DB_XREF=est:ia08f10.x1 /UG=Hs.74502 chymotrypsinogen B1 AW584011 chymotrypsinogen B2 CTRB2 440387 NM_001025200 0006508 // proteolysis // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214412_at AI218431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI218431 /FEA=EST /DB_XREF=gi:3798246 /DB_XREF=est:qh24d10.x1 /CLONE=IMAGE:1845619 /UG=Hs.83363 coagulation factor VIII-associated (intronic transcript) AI218431 H2A histone family, member B1 /// H2A histone family, member B2 /// H2A histone family, member B3 H2AFB1 /// H2AFB2 /// H2AFB3 83740 /// 474381 /// 474382 NM_001017990 /// NM_001017991 /// NM_080720 0006334 // nucleosome assembly // inferred from direct assay /// 0006397 // mRNA processing // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0035327 // transcriptionally active chromatin // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214413_at AV647713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV647713 /FEA=EST /DB_XREF=gi:9868727 /DB_XREF=est:AV647713 /CLONE=GLCBBB11 /UG=Hs.161640 tyrosine aminotransferase AV647713 tyrosine aminotransferase TAT 6898 NM_000353 0006103 // 2-oxoglutarate metabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // inferred from direct assay /// 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // non-traceable author statement /// 0004838 // L-tyrosine:2-oxoglutarate aminotransferase activity // traceable author statement /// 0016597 // amino acid binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0080130 // L-phenylalanine:2-oxoglutarate aminotransferase activity // inferred from electronic annotation 214414_x_at T50399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T50399 /FEA=EST /DB_XREF=gi:652259 /DB_XREF=est:yb30b11.s1 /CLONE=IMAGE:72669 /UG=Hs.251577 hemoglobin, alpha 1 T50399 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214415_at N58120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N58120 /FEA=EST /DB_XREF=gi:1202010 /DB_XREF=est:yv65a07.s1 /CLONE=IMAGE:247572 /UG=Hs.262869 plasminogen-like N58120 plasminogen-like B1 /// plasminogen-like B2 PLGLB1 /// PLGLB2 5342 /// 5343 NM_001032392 /// NM_002665 0005576 // extracellular region // inferred from electronic annotation 214416_at AA654415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA654415 /FEA=EST /DB_XREF=gi:2590569 /DB_XREF=est:nt03g09.s1 /CLONE=IMAGE:1192096 /UG=Hs.322808 ESTs, Moderately similar to AMYP_HUMAN ALPHA-AMYLASE, PANCREATIC PRECURSOR H.sapiens AA654415 214417_s_at N39010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N39010 /FEA=EST /DB_XREF=gi:1162217 /DB_XREF=est:yv22a08.s1 /CLONE=IMAGE:243446 /UG=Hs.81073 fetuin B N39010 214418_at AI656822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI656822 /FEA=EST /DB_XREF=gi:4740801 /DB_XREF=est:tt54c05.x1 /CLONE=IMAGE:2244584 /UG=Hs.97823 Homo sapiens mRNA; cDNA DKFZp434D024 (from clone DKFZp434D024) AI656822 cancer/testis antigen 62 CT62 196993 NM_001102658 /// XM_006720429 214419_s_at AV646536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV646536 /FEA=EST /DB_XREF=gi:9867550 /DB_XREF=est:AV646536 /CLONE=GLCAOD11 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 AV646536 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 214420_s_at AV657878 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV657878 /FEA=EST /DB_XREF=gi:9878892 /DB_XREF=est:AV657878 /CLONE=GLCFGE11 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 AV657878 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 214421_x_at AV652420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV652420 /FEA=EST /DB_XREF=gi:9873434 /DB_XREF=est:AV652420 /CLONE=GLCDAB09 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 AV652420 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 214422_at T93562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T93562 /FEA=EST /DB_XREF=gi:726735 /DB_XREF=est:ye17b01.s1 /CLONE=IMAGE:117961 /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B T93562 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_001244713 /// NM_001244724 /// NM_002874 0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 214423_x_at AV652403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV652403 /FEA=EST /DB_XREF=gi:9873417 /DB_XREF=est:AV652403 /CLONE=GLCDAA04 /UG=Hs.234234 aldolase B, fructose-bisphosphate AV652403 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 214424_s_at AV650852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV650852 /FEA=EST /DB_XREF=gi:9871866 /DB_XREF=est:AV650852 /CLONE=GLCCJB07 /UG=Hs.234234 aldolase B, fructose-bisphosphate AV650852 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 214425_at AV645756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV645756 /FEA=EST /DB_XREF=gi:9866770 /DB_XREF=est:AV645756 /CLONE=GLCAED06 /UG=Hs.76177 alpha-1-microglobulinbikunin precursor AV645756 alpha-1-microglobulin/bikunin precursor AMBP 259 NM_001633 0007155 // cell adhesion // non-traceable author statement /// 0007565 // female pregnancy // non-traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0042167 // heme catabolic process // non-traceable author statement /// 0046329 // negative regulation of JNK cascade // traceable author statement /// 0050777 // negative regulation of immune response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019855 // calcium channel inhibitor activity // non-traceable author statement /// 0019862 // IgA binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0036094 // small molecule binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046904 // calcium oxalate binding // non-traceable author statement 214426_x_at BF062223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062223 /FEA=EST /DB_XREF=gi:10821121 /DB_XREF=est:7k74c04.x1 /CLONE=IMAGE:3480967 /UG=Hs.79018 chromatin assembly factor 1, subunit A (p150) BF062223 chromatin assembly factor 1, subunit A (p150) CHAF1A 10036 NM_005483 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement /// 0070087 // chromo shadow domain binding // inferred from physical interaction 214427_at NM_006170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006170.1 /DEF=Homo sapiens nucleolar protein 1 (120kD) (NOL1), mRNA. /FEA=CDS /GEN=NOL1 /PROD=nucleolar protein 1 (120kD) /DB_XREF=gi:5453791 /UG=Hs.15243 nucleolar protein 1 (120kD) /FL=gb:BC000656.1 gb:M32110.1 gb:NM_006170.1 NM_006170 NOP2 nucleolar protein NOP2 4839 NM_001033714 /// NM_001258308 /// NM_001258309 /// NM_001258310 /// NM_006170 /// XM_005253691 0006364 // rRNA processing // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214428_x_at K02403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K02403.1 /DEF=Human complement component C4A mRNA, complete cds. /FEA=mRNA /GEN=C4A /PROD=complement component C4A /DB_XREF=gi:187768 /UG=Hs.170250 complement component 4A /FL=gb:K02403.1 K02403 complement component 4A (Rodgers blood group) /// complement component 4B (Chido blood group) /// complement component 4B (Chido blood group), copy 2 C4A /// C4B /// C4B_2 720 /// 721 /// 100293534 NM_001002029 /// NM_001242823 /// NM_001252204 /// NM_007293 /// XM_006725947 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006956 // complement activation // inferred from genetic interaction /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0008228 // opsonization // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0032490 // detection of molecule of bacterial origin // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 2000427 // positive regulation of apoptotic cell clearance // inferred from genetic interaction 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0044216 // other organism cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // inferred from direct assay /// 0001849 // complement component C1q binding // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from direct assay 214429_at U47635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U47635.1 /DEF=Human D13S824E locus mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:1669390 /UG=Hs.79877 myotubularin related protein 6 /FL=gb:U47635.1 U47635 myotubularin related protein 6 MTMR6 9107 NM_004685 /// XM_006719891 /// XM_006719892 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 214430_at NM_000169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000169.1 /DEF=Homo sapiens galactosidase, alpha (GLA), mRNA. /FEA=CDS /GEN=GLA /PROD=galactosidase, alpha /DB_XREF=gi:4504008 /UG=Hs.69089 galactosidase, alpha /FL=gb:BC002689.1 gb:NM_000169.1 NM_000169 galactosidase, alpha GLA 2717 NM_000169 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0009451 // RNA modification // inferred from electronic annotation /// 0016139 // glycoside catabolic process // not recorded /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0046477 // glycosylceramide catabolic process // not recorded /// 0046477 // glycosylceramide catabolic process // inferred from sequence or structural similarity /// 0046479 // glycosphingolipid catabolic process // traceable author statement /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005764 // lysosome // inferred from mutant phenotype /// 0005764 // lysosome // traceable author statement /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004557 // alpha-galactosidase activity // inferred from direct assay /// 0004557 // alpha-galactosidase activity // inferred from mutant phenotype /// 0004557 // alpha-galactosidase activity // traceable author statement /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // traceable author statement /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016936 // galactoside binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0052692 // raffinose alpha-galactosidase activity // inferred from electronic annotation 214431_at NM_003875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003875.1 /DEF=Homo sapiens guanine monphosphate synthetase (GMPS), mRNA. /FEA=CDS /GEN=GMPS /PROD=guanine monophosphate synthetase /DB_XREF=gi:4504034 /UG=Hs.5398 guanine monphosphate synthetase /FL=gb:NM_003875.1 gb:U10860.1 NM_003875 guanine monphosphate synthase GMPS 8833 NM_003875 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006177 // GMP biosynthetic process // inferred from electronic annotation /// 0006529 // asparagine biosynthetic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003921 // GMP synthase activity // traceable author statement /// 0003922 // GMP synthase (glutamine-hydrolyzing) activity // inferred from electronic annotation /// 0004066 // asparagine synthase (glutamine-hydrolyzing) activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 214432_at NM_000703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000703.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, alpha 3 polypeptide (ATP1A3), mRNA. /FEA=CDS /GEN=ATP1A3 /PROD=ATPase, Na+K+ transporting, alpha 3polypeptide /DB_XREF=gi:4502272 /UG=Hs.274371 ATPase, Na+K+ transporting, alpha 3 polypeptide /FL=gb:NM_000703.1 NM_000703 ATPase, Na+/K+ transporting, alpha 3 polypeptide /// uncharacterized LOC101927137 ATP1A3 /// LOC101927137 478 /// 101927137 NM_001256213 /// NM_001256214 /// NM_152296 /// XM_005258953 /// XR_246167 /// XR_246168 /// XR_246169 /// XR_246170 /// XR_246171 /// XR_246172 /// XR_246173 /// XR_252798 /// XR_252799 /// XR_252800 /// XR_252801 /// XR_252802 /// XR_252803 /// XR_252804 /// XR_428788 /// XR_428789 /// XR_428790 /// XR_428791 /// XR_428792 /// XR_428793 /// XR_428794 /// XR_428795 /// XR_428796 /// XR_432624 /// XR_432625 /// XR_432626 /// XR_432627 /// XR_432628 /// XR_432629 /// XR_432630 /// XR_432631 /// XR_432632 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0044326 // dendritic spine neck // inferred from electronic annotation /// 0044327 // dendritic spine head // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214433_s_at NM_003944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003944.1 /DEF=Homo sapiens selenium binding protein 1 (SELENBP1), mRNA. /FEA=CDS /GEN=SELENBP1 /PROD=selenium binding protein 1 /DB_XREF=gi:4506872 /UG=Hs.288973 selenium binding protein 1 /FL=gb:U29091.1 gb:NM_003944.1 NM_003944 selenium binding protein 1 SELENBP1 8991 NM_001258288 /// NM_001258289 /// NM_003944 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008430 // selenium binding // inferred from electronic annotation 214434_at AB007877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007877.1 /DEF=Homo sapiens KIAA0417 mRNA, complete cds. /FEA=mRNA /GEN=KIAA0417 /DB_XREF=gi:2887408 /UG=Hs.12385 KIAA0417 gene product /FL=gb:AB007877.1 AB007877 heat shock 70kDa protein 12A HSPA12A 259217 NM_025015 /// XM_005269672 /// XM_005269673 /// XM_006717746 /// XM_006717747 0006950 // response to stress // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 214435_x_at NM_005402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005402.1 /DEF=Homo sapiens v-ral simian leukemia viral oncogene homolog A (ras related) (RALA), mRNA. /FEA=CDS /GEN=RALA /PROD=v-ral simian leukemia viral oncogene homolog A(ras related) /DB_XREF=gi:4885568 /UG=Hs.288757 v-ral simian leukemia viral oncogene homolog A (ras related) /FL=gb:M29893.1 gb:NM_005402.1 NM_005402 v-ral simian leukemia viral oncogene homolog A (ras related) RALA 5898 NM_005402 /// XM_006715762 /// XM_006715763 0000910 // cytokinesis // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0051665 // membrane raft localization // inferred from direct assay /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay 214436_at AF176518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF176518.1 /DEF=Homo sapiens leucine-rich repeat-containing F-box protein FBL2 mRNA, complete cds. /FEA=mRNA /PROD=F-box protein FBL2 /DB_XREF=gi:6063089 /UG=Hs.6092 f-box and leucine-rich repeat protein 2 /FL=gb:AF186273.1 gb:AF176518.1 gb:AF174589.1 AF176518 F-box and leucine-rich repeat protein 2 FBXL2 25827 NM_001171713 /// NM_012157 /// XM_005265014 /// XM_005265015 /// XM_005265016 /// XM_005265017 /// XR_427262 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 214437_s_at NM_005412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005412.1 /DEF=Homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), mRNA. /FEA=CDS /GEN=SHMT2 /PROD=serine hydroxymethyltransferase 2(mitochondrial) /DB_XREF=gi:4885594 /UG=Hs.75069 serine hydroxymethyltransferase 2 (mitochondrial) /FL=gb:NM_005412.1 NM_005412 serine hydroxymethyltransferase 2 (mitochondrial) SHMT2 6472 NM_001166356 /// NM_001166357 /// NM_001166358 /// NM_001166359 /// NM_005412 /// NR_029415 /// NR_029416 /// NR_029417 /// NR_048562 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019264 // glycine biosynthetic process from serine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004372 // glycine hydroxymethyltransferase activity // inferred from direct assay /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008732 // L-allo-threonine aldolase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 214438_at M60721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M60721.1 /DEF=Human homeobox gene, complete cds. /FEA=mRNA /DB_XREF=gi:183789 /UG=Hs.74870 H2.0 (Drosophila)-like homeo box 1 /FL=gb:NM_021958.1 gb:M60721.1 M60721 H2.0-like homeobox HLX 3142 NM_021958 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045627 // positive regulation of T-helper 1 cell differentiation // inferred from electronic annotation /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 214439_x_at AF043899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043899.1 /DEF=Homo sapiens amphiphysin IIc1 mRNA, complete cds. /FEA=CDS /PROD=amphiphysin IIc1 /DB_XREF=gi:3064256 /UG=Hs.193163 bridging integrator 1 /FL=gb:AF043899.1 AF043899 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 214440_at NM_000662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000662.1 /DEF=Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), mRNA. /FEA=CDS /GEN=NAT1 /PROD=N-acetyltransferase 1 /DB_XREF=gi:4505334 /UG=Hs.155956 N-acetyltransferase 1 (arylamine N-acetyltransferase) /FL=gb:NM_000662.1 NM_000662 N-acetyltransferase 1 (arylamine N-acetyltransferase) NAT1 9 NM_000662 /// NM_001160170 /// NM_001160171 /// NM_001160172 /// NM_001160173 /// NM_001160174 /// NM_001160175 /// NM_001160176 /// NM_001160179 /// NM_001291962 /// XM_006716410 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004060 // arylamine N-acetyltransferase activity // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 214441_at NM_005819 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005819.1 /DEF=Homo sapiens syntaxin 6 (STX6), mRNA. /FEA=CDS /GEN=STX6 /PROD=syntaxin 6 /DB_XREF=gi:5032130 /UG=Hs.157144 syntaxin 6 /FL=gb:AJ002078.1 gb:NM_005819.1 NM_005819 syntaxin 6 STX6 10228 NM_001286210 /// NM_005819 /// XM_005244824 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006906 // vesicle fusion // inferred from physical interaction /// 0007032 // endosome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0030136 // clathrin-coated vesicle // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 214442_s_at AF077953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF077953.1 /DEF=Homo sapiens protein inhibitor of activated STAT protein PIASx-alpha mRNA, complete cds. /FEA=CDS /PROD=protein inhibitor of activated STAT proteinPIASx-alpha /DB_XREF=gi:3643112 /UG=Hs.111323 Protein inhibitor of activated STAT X /FL=gb:AF077953.1 AF077953 protein inhibitor of activated STAT, 2 PIAS2 9063 NM_004671 /// NM_173206 /// XM_005258377 /// XM_005258379 /// XM_005258381 /// XM_005258382 /// XM_005258383 /// XM_006722571 /// XM_006722572 /// XM_006722573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 214443_at NM_006505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006505.1 /DEF=Homo sapiens poliovirus receptor (PVR), mRNA. /FEA=CDS /GEN=PVR /PROD=poliovirus receptor /DB_XREF=gi:5729994 /UG=Hs.321018 poliovirus receptor /FL=gb:NM_006505.1 NM_006505 poliovirus receptor PVR 5817 NM_001135768 /// NM_001135769 /// NM_001135770 /// NM_006505 /// XM_005259120 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 214444_s_at NM_006505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006505.1 /DEF=Homo sapiens poliovirus receptor (PVR), mRNA. /FEA=CDS /GEN=PVR /PROD=poliovirus receptor /DB_XREF=gi:5729994 /UG=Hs.321018 poliovirus receptor /FL=gb:NM_006505.1 NM_006505 poliovirus receptor PVR 5817 NM_001135768 /// NM_001135769 /// NM_001135770 /// NM_006505 /// XM_005259120 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 214445_at NM_012081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012081.1 /DEF=Homo sapiens ELL-RELATED RNA POLYMERASE II, ELONGATION FACTOR (ELL2), mRNA. /FEA=CDS /GEN=ELL2 /PROD=ELL-RELATED RNA POLYMERASE II, ELONGATIONFACTOR /DB_XREF=gi:6912353 /UG=Hs.173334 ELL-RELATED RNA POLYMERASE II, ELONGATION FACTOR /FL=gb:NM_012081.1 NM_012081 elongation factor, RNA polymerase II, 2 ELL2 22936 NM_012081 /// XM_006714574 /// XM_006714575 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation 214446_at NM_012081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012081.1 /DEF=Homo sapiens ELL-RELATED RNA POLYMERASE II, ELONGATION FACTOR (ELL2), mRNA. /FEA=CDS /GEN=ELL2 /PROD=ELL-RELATED RNA POLYMERASE II, ELONGATIONFACTOR /DB_XREF=gi:6912353 /UG=Hs.173334 ELL-RELATED RNA POLYMERASE II, ELONGATION FACTOR /FL=gb:NM_012081.1 NM_012081 elongation factor, RNA polymerase II, 2 ELL2 22936 NM_012081 /// XM_006714574 /// XM_006714575 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation 214447_at NM_005238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005238.1 /DEF=Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1), mRNA. /FEA=CDS /GEN=ETS1 /PROD=v-ets avian erythroblastosis virus E26 oncogenehomolog 1 /DB_XREF=gi:4885218 /UG=Hs.248109 v-ets avian erythroblastosis virus E26 oncogene homolog 1 /FL=gb:J04101.1 gb:NM_005238.1 NM_005238 v-ets avian erythroblastosis virus E26 oncogene homolog 1 ETS1 2113 NM_001143820 /// NM_001162422 /// NM_005238 /// XM_005271428 0001666 // response to hypoxia // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010715 // regulation of extracellular matrix disassembly // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030578 // PML body organization // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0048870 // cell motility // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from mutant phenotype /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035035 // histone acetyltransferase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214448_x_at NM_002503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002503.1 /DEF=Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), mRNA. /FEA=CDS /GEN=NFKBIB /PROD=nuclear factor of kappa light polypeptide geneenhancer in B-cells inhibitor, beta /DB_XREF=gi:4505384 /UG=Hs.9731 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta /FL=gb:NM_002503.1 NM_002503 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta NFKBIB 4793 NM_001001716 /// NM_001243116 /// NM_002503 /// NR_040515 /// XM_006723226 /// XM_006723227 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214449_s_at NM_012249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012249.1 /DEF=Homo sapiens ras-like protein (TC10), mRNA. /FEA=CDS /GEN=TC10 /PROD=ras-like protein /DB_XREF=gi:6912695 /UG=Hs.250697 ras-like protein /FL=gb:M31470.1 gb:NM_012249.1 NM_012249 ras homolog family member Q RHOQ 23433 NM_012249 /// XM_005264229 0006184 // GTP catabolic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0032427 // GBD domain binding // inferred from physical interaction 214450_at NM_001335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001335.1 /DEF=Homo sapiens cathepsin W (lymphopain) (CTSW), mRNA. /FEA=CDS /GEN=CTSW /PROD=cathepsin W (lymphopain) /DB_XREF=gi:4503156 /UG=Hs.87450 cathepsin W (lymphopain) /FL=gb:AF013611.1 gb:NM_001335.1 NM_001335 cathepsin W CTSW 1521 NM_001335 0006508 // proteolysis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement 0016020 // membrane // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214451_at NM_003221 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003221.1 /DEF=Homo sapiens transcription factor AP-2 beta (activating enhancer-binding protein 2 beta) (TFAP2B), mRNA. /FEA=CDS /GEN=TFAP2B /PROD=transcription factor AP-2 beta (activatingenhancer-binding protein 2 beta) /DB_XREF=gi:4507442 /UG=Hs.33102 transcription factor AP-2 beta (activating enhancer-binding protein 2 beta) /FL=gb:NM_003221.1 NM_003221 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) TFAP2B 7021 NM_003221 /// XM_006715176 /// XM_006715177 /// XM_006715178 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0003091 // renal water homeostasis // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007423 // sensory organ development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from expression pattern /// 0010960 // magnesium ion homeostasis // inferred from sequence or structural similarity /// 0030510 // regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from sequence or structural similarity /// 0035137 // hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045595 // regulation of cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype /// 0055062 // phosphate ion homeostasis // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0055075 // potassium ion homeostasis // inferred from sequence or structural similarity /// 0055078 // sodium ion homeostasis // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from sequence or structural similarity /// 0072044 // collecting duct development // inferred from sequence or structural similarity /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 0097275 // cellular ammonia homeostasis // inferred from sequence or structural similarity /// 0097276 // cellular creatinine homeostasis // inferred from sequence or structural similarity /// 0097277 // cellular urea homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from direct assay 214452_at NM_005504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005504.1 /DEF=Homo sapiens branched chain aminotransferase 1, cytosolic (BCAT1), mRNA. /FEA=CDS /GEN=BCAT1 /PROD=branched chain aminotransferase 1, cytosolic /DB_XREF=gi:5031606 /UG=Hs.157205 branched chain aminotransferase 1, cytosolic /FL=gb:U21551.1 gb:NM_005504.1 NM_005504 branched chain amino-acid transaminase 1, cytosolic BCAT1 586 NM_001178091 /// NM_001178092 /// NM_001178093 /// NM_001178094 /// NM_005504 /// XM_005253460 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation 214453_s_at NM_006417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006417.1 /DEF=Homo sapiens interferon-induced, hepatitis C-associated microtubular aggregate protein (44kD) (MTAP44), mRNA. /FEA=CDS /GEN=MTAP44 /PROD=interferon-induced, hepatitis C-associatedmicrotubular aggregate protein (44kD) /DB_XREF=gi:5453743 /UG=Hs.82316 interferon-induced, hepatitis C-associated microtubular aggregate protein (44kD) /FL=gb:NM_006417.1 NM_006417 interferon-induced protein 44 IFI44 10561 NM_006417 /// XM_005270380 /// XR_246226 /// XR_426586 0009615 // response to virus // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 214454_at NM_014244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014244.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 1, mRNA. /FEA=CDS /GEN=ADAMTS2 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-2, isoform 1 /DB_XREF=gi:7656866 /UG=Hs.120330 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 /FL=gb:NM_014244.1 NM_014244 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ADAMTS2 9509 NM_014244 /// NM_021599 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214455_at NM_003526 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003526.1 /DEF=Homo sapiens H2B histone family, member L (H2BFL), mRNA. /FEA=CDS /GEN=H2BFL /PROD=H2B histone family, member L /DB_XREF=gi:4504272 /UG=Hs.239884 H2B histone family, member L /FL=gb:NM_003526.1 NM_003526 histone cluster 1, H2bc /// histone cluster 1, H2be /// histone cluster 1, H2bf /// histone cluster 1, H2bg /// histone cluster 1, H2bi HIST1H2BC /// HIST1H2BE /// HIST1H2BF /// HIST1H2BG /// HIST1H2BI 8339 /// 8343 /// 8344 /// 8346 /// 8347 NM_003518 /// NM_003522 /// NM_003523 /// NM_003525 /// NM_003526 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214456_x_at M23699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M23699.1 /DEF=Homo sapiens serum amyloid A2-alpha (SAA2) mRNA, complete cds. /FEA=CDS /GEN=SAA2 /PROD=serum amyloid A2-alpha /DB_XREF=gi:758680 /UG=Hs.332053 serum amyloid A2 /FL=gb:M23699.1 gb:M23700.1 M23699 serum amyloid A1 /// serum amyloid A2 SAA1 /// SAA2 6288 /// 6289 NM_000331 /// NM_001127380 /// NM_001178006 /// NM_030754 /// NM_199161 0006953 // acute-phase response // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // non-traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030593 // neutrophil chemotaxis // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // non-traceable author statement /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from direct assay /// 0050708 // regulation of protein secretion // non-traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050716 // positive regulation of interleukin-1 secretion // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation 214457_at NM_006735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006735.1 /DEF=Homo sapiens homeo box A2 (HOXA2), mRNA. /FEA=CDS /GEN=HOXA2 /PROD=homeo box A2 /DB_XREF=gi:10140846 /UG=Hs.58116 homeo box A2 /FL=gb:NM_006735.1 NM_006735 homeobox A2 HOXA2 3199 NM_006735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007379 // segment specification // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021568 // rhombomere 2 development // inferred from electronic annotation /// 0021569 // rhombomere 3 development // inferred from electronic annotation /// 0021658 // rhombomere 3 morphogenesis // inferred from electronic annotation /// 0035284 // brain segmentation // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214458_at AF230877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF230877.1 /DEF=Homo sapiens MIP-T3 mRNA, complete cds. /FEA=CDS /PROD=MIP-T3 /DB_XREF=gi:8572064 /UG=Hs.152701 microtubule-interacting protein that associates with TRAF3; DKFZP434F124 protein /FL=gb:AF230877.1 AF230877 TNF receptor-associated factor 3 interacting protein 1 TRAF3IP1 26146 NM_001139490 /// NM_015650 /// XM_006712412 /// XM_006712413 /// XM_006712414 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation 214459_x_at M12679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M12679.1 /DEF=Human Cw1 antigen mRNA, complete cds. /FEA=mRNA /GEN=HLA-C /DB_XREF=gi:187911 /UG=Hs.274485 Cw1 antigen /FL=gb:M12679.1 M12679 major histocompatibility complex, class I, C HLA-C 3107 NM_001243042 /// NM_002117 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay 214460_at NM_002338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002338.1 /DEF=Homo sapiens limbic system-associated membrane protein (LSAMP), mRNA. /FEA=CDS /GEN=LSAMP /PROD=limbic system-associated membrane protein /DB_XREF=gi:4505024 /UG=Hs.26479 limbic system-associated membrane protein /FL=gb:U41901.1 gb:NM_002338.1 NM_002338 limbic system-associated membrane protein LSAMP 4045 NM_002338 /// XM_005247454 /// XM_006713638 0007155 // cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214461_at NM_004139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004139.1 /DEF=Homo sapiens lipopolysaccharide-binding protein (LBP), mRNA. /FEA=CDS /GEN=LBP /PROD=lipopolysaccharide-binding protein /DB_XREF=gi:11345447 /UG=Hs.154078 lipopolysaccharide-binding protein /FL=gb:NM_004139.1 gb:AF105067.1 NM_004139 lipopolysaccharide binding protein LBP 3929 NM_004139 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002232 // leukocyte chemotaxis involved in inflammatory response // inferred from electronic annotation /// 0002281 // macrophage activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from expression pattern /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0008228 // opsonization // inferred by curator /// 0008228 // opsonization // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032490 // detection of molecule of bacterial origin // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // inferred by curator /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0060265 // positive regulation of respiratory burst involved in inflammatory response // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001530 // lipopolysaccharide binding // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0070891 // lipoteichoic acid binding // inferred from direct assay 214462_at NM_004232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004232.1 /DEF=Homo sapiens STAT induced STAT inhibitor-4 (CIS4), mRNA. /FEA=CDS /GEN=CIS4 /PROD=STAT induced STAT inhibitor-4 /DB_XREF=gi:4757991 /UG=Hs.44439 STAT induced STAT inhibitor-4 /FL=gb:AB006968.1 gb:NM_004232.1 NM_004232 suppressor of cytokine signaling 6 SOCS6 9306 NM_004232 /// XM_005266783 /// XM_006722577 0006952 // defense response // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 214463_x_at NM_003541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003541.1 /DEF=Homo sapiens H4 histone family, member D (H4FD), mRNA. /FEA=CDS /GEN=H4FD /PROD=H4 histone family, member D /DB_XREF=gi:4504306 /UG=Hs.91031 H4 histone family, member D /FL=gb:NM_003541.1 NM_003541 histone cluster 1, H4j HIST1H4J 8363 NM_021968 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214464_at NM_003607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003607.1 /DEF=Homo sapiens Ser-Thr protein kinase related to the myotonic dystrophy protein kinase (PK428), mRNA. /FEA=CDS /GEN=PK428 /PROD=ser-Thr protein kinase related to the myotonicdystrophy protein kinase /DB_XREF=gi:4505830 /UG=Hs.44708 Ser-Thr protein kinase related to the myotonic dystrophy protein kinase /FL=gb:U59305.1 gb:NM_003607.1 NM_003607 CDC42 binding protein kinase alpha (DMPK-like) CDC42BPA 8476 NM_003607 /// NM_014826 /// XM_005273317 /// XM_005273318 /// XM_005273320 /// XM_005273321 /// XM_005273322 /// XM_005273323 /// XM_005273324 /// XM_006711834 /// XM_006711835 /// XM_006711836 /// XM_006711837 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007097 // nuclear migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214465_at NM_000608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000608.1 /DEF=Homo sapiens orosomucoid 2 (ORM2), mRNA. /FEA=CDS /GEN=ORM2 /PROD=orosomucoid 2 /DB_XREF=gi:4505528 /UG=Hs.278388 orosomucoid 2 /FL=gb:NM_000608.1 NM_000608 orosomucoid 1 /// orosomucoid 2 ORM1 /// ORM2 5004 /// 5005 NM_000607 /// NM_000608 0002682 // regulation of immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214466_at NM_005266 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005266.2 /DEF=Homo sapiens gap junction protein, alpha 5, 40kD (connexin 40) (GJA5), mRNA. /FEA=CDS /GEN=GJA5 /PROD=gap junction protein, alpha 5, 40kD (connexin40) /DB_XREF=gi:6631082 /UG=Hs.247926 gap junction protein, alpha 5, 40kD (connexin 40) /FL=gb:NM_005266.2 NM_005266 gap junction protein, alpha 5, 40kDa GJA5 2702 NM_005266 /// NM_181703 /// XM_005272951 0001501 // skeletal system development // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0003071 // renal system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0003073 // regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0003105 // negative regulation of glomerular filtration // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from mutant phenotype /// 0003158 // endothelium development // inferred from electronic annotation /// 0003161 // cardiac conduction system development // inferred from electronic annotation /// 0003174 // mitral valve development // inferred from mutant phenotype /// 0003193 // pulmonary valve formation // inferred from mutant phenotype /// 0003281 // ventricular septum development // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0003284 // septum primum development // inferred from electronic annotation /// 0003294 // atrial ventricular junction remodeling // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from electronic annotation /// 0010652 // positive regulation of cell communication by chemical coupling // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from direct assay /// 0016264 // gap junction assembly // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035922 // foramen ovale closure // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from mutant phenotype /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from electronic annotation /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from electronic annotation /// 0086053 // AV node cell to bundle of His cell communication by electrical coupling // inferred from mutant phenotype /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred from direct assay /// 0086065 // cell communication involved in cardiac conduction // inferred from electronic annotation /// 0086067 // AV node cell to bundle of His cell communication // inferred from electronic annotation /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from electronic annotation /// 1900133 // regulation of renin secretion into blood stream // inferred from electronic annotation /// 1900825 // regulation of membrane depolarization during cardiac muscle cell action potential // inferred from electronic annotation /// 1990029 // vasomotion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005921 // gap junction // inferred from direct assay /// 0005922 // connexon complex // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005243 // gap junction channel activity // inferred from electronic annotation /// 0055077 // gap junction hemi-channel activity // inferred from direct assay /// 0071253 // connexin binding // inferred from electronic annotation /// 0086075 // gap junction channel activity involved in cardiac conduction electrical coupling // inferred from direct assay /// 0086075 // gap junction channel activity involved in cardiac conduction electrical coupling // inferred from mutant phenotype /// 0086077 // gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling // inferred from direct assay 214467_at NM_003608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003608.1 /DEF=Homo sapiens G protein-coupled receptor 65 (GPR65), mRNA. /FEA=CDS /GEN=GPR65 /PROD=G protein-coupled receptor 65 /DB_XREF=gi:4507420 /UG=Hs.131924 G protein-coupled receptor 65 /FL=gb:NM_003608.1 NM_003608 G protein-coupled receptor 65 GPR65 8477 NM_003608 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0010447 // response to acidity // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay 214468_at D00943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D00943.1 /DEF=Homo sapiens mRNA for cardiac alpha-myosin heavy chain, complete cds. /FEA=CDS /PROD=cardiac alpha-myosin heavy chain /DB_XREF=gi:219523 /UG=Hs.278432 myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) /FL=gb:D00943.1 D00943 myosin, heavy chain 6, cardiac muscle, alpha MYH6 4624 NM_002471 /// XM_005267694 /// XM_005267695 /// XM_006720151 /// XM_006720152 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0002026 // regulation of the force of heart contraction // inferred from direct assay /// 0002026 // regulation of the force of heart contraction // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006936 // muscle contraction // inferred from direct assay /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from sequence or structural similarity /// 0007512 // adult heart development // inferred from mutant phenotype /// 0007522 // visceral muscle development // inferred from sequence or structural similarity /// 0008016 // regulation of heart contraction // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0043462 // regulation of ATPase activity // inferred from sequence or structural similarity /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060420 // regulation of heart growth // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation 0000146 // microfilament motor activity // inferred from direct assay /// 0000146 // microfilament motor activity // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030898 // actin-dependent ATPase activity // inferred from mutant phenotype 214469_at NM_021052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021052.1 /DEF=Homo sapiens H2A histone family, member A (H2AFA), mRNA. /FEA=CDS /GEN=H2AFA /PROD=H2A histone family, member A /DB_XREF=gi:10645194 /UG=Hs.121017 H2A histone family, member A /FL=gb:NM_021052.1 NM_021052 histone cluster 1, H2ae HIST1H2AE 3012 NM_021052 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214470_at NM_002258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002258.1 /DEF=Homo sapiens killer cell lectin-like receptor subfamily B, member 1 (KLRB1), mRNA. /FEA=CDS /GEN=KLRB1 /PROD=killer cell lectin-like receptor subfamily B,member 1 /DB_XREF=gi:4504878 /UG=Hs.169824 killer cell lectin-like receptor subfamily B, member 1 /FL=gb:NM_002258.1 gb:U11276.1 NM_002258 killer cell lectin-like receptor subfamily B, member 1 KLRB1 3820 NM_002258 0007166 // cell surface receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 214471_x_at NM_000894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000894.1 /DEF=Homo sapiens luteinizing hormone beta polypeptide (LHB), mRNA. /FEA=CDS /GEN=LHB /PROD=luteinizing hormone beta polypeptide /DB_XREF=gi:4504988 /UG=Hs.154704 luteinizing hormone beta polypeptide /FL=gb:NM_000894.1 NM_000894 chorionic gonadotropin, beta polypeptide 1 /// luteinizing hormone beta polypeptide CGB1 /// LHB 3972 /// 114335 NM_000894 /// NM_033377 /// XM_005258478 0006701 // progesterone biosynthetic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0016486 // peptide hormone processing // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 214472_at NM_003530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003530.1 /DEF=Homo sapiens H3 histone family, member B (H3FB), mRNA. /FEA=CDS /GEN=H3FB /PROD=H3 histone family, member B /DB_XREF=gi:4504282 /UG=Hs.143042 H3 histone family, member B /FL=gb:NM_003530.1 NM_003530 histone cluster 1, H2ad /// histone cluster 1, H3a /// histone cluster 1, H3b /// histone cluster 1, H3c /// histone cluster 1, H3d /// histone cluster 1, H3e /// histone cluster 1, H3f /// histone cluster 1, H3g /// histone cluster 1, H3h /// histone cluster 1, H3i /// histone cluster 1, H3j HIST1H2AD /// HIST1H3A /// HIST1H3B /// HIST1H3C /// HIST1H3D /// HIST1H3E /// HIST1H3F /// HIST1H3G /// HIST1H3H /// HIST1H3I /// HIST1H3J 3013 /// 8350 /// 8351 /// 8352 /// 8353 /// 8354 /// 8355 /// 8356 /// 8357 /// 8358 /// 8968 NM_003529 /// NM_003530 /// NM_003531 /// NM_003532 /// NM_003533 /// NM_003534 /// NM_003535 /// NM_003536 /// NM_003537 /// NM_021018 /// NM_021065 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214473_x_at NM_005395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005395.1 /DEF=Homo sapiens postmeiotic segregation increased 2-like 9 (PMS2L9), mRNA. /FEA=CDS /GEN=PMS2L9 /PROD=postmeiotic segregation increased 2-like 9 /DB_XREF=gi:4885552 /UG=Hs.301862 postmeiotic segregation increased 2-like 9 /FL=gb:NM_005395.1 NM_005395 postmeiotic segregation increased 2 pseudogene 3 PMS2P3 5387 NM_001003686 /// NM_005395 /// NR_028059 0006298 // mismatch repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0032300 // mismatch repair complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 214474_at NM_005399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005399.1 /DEF=Homo sapiens protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2), mRNA. /FEA=CDS /GEN=PRKAB2 /PROD=protein kinase, AMP-activated, beta 2non-catalytic subunit /DB_XREF=gi:4885560 /UG=Hs.50732 protein kinase, AMP-activated, beta 2 non-catalytic subunit /FL=gb:NM_005399.1 NM_005399 protein kinase, AMP-activated, beta 2 non-catalytic subunit PRKAB2 5565 NM_005399 /// NR_103870 /// NR_103871 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay 0004679 // AMP-activated protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 214475_x_at AF127764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF127764.1 /DEF=Homo sapiens calpain 3 (CAPN3) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=CAPN3 /PROD=calpain 3 /DB_XREF=gi:4704751 /UG=Hs.40300 calpain 3, (p94) /FL=gb:AF127764.1 AF127764 calpain 3, (p94) CAPN3 825 NM_000070 /// NM_024344 /// NM_173087 /// NM_173088 /// NM_173089 /// NM_173090 /// NM_212465 /// NR_027911 /// NR_027912 0001896 // autolysis // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0014718 // positive regulation of satellite cell activation involved in skeletal muscle regeneration // inferred from sequence or structural similarity /// 0014850 // response to muscle activity // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0030239 // myofibril assembly // traceable author statement /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0045661 // regulation of myoblast differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0061061 // muscle structure development // inferred from sequence or structural similarity /// 0070315 // G1 to G0 transition involved in cell differentiation // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0071472 // cellular response to salt stress // inferred from sequence or structural similarity /// 0072657 // protein localization to membrane // inferred from sequence or structural similarity /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0008307 // structural constituent of muscle // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from sequence or structural similarity /// 0031432 // titin binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0055103 // ligase regulator activity // inferred from direct assay 214476_at NM_005423 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005423.1 /DEF=Homo sapiens trefoil factor 2 (spasmolytic protein 1) (TFF2), mRNA. /FEA=CDS /GEN=TFF2 /PROD=trefoil factor 2 (spasmolytic protein 1) /DB_XREF=gi:4885628 /UG=Hs.2979 trefoil factor 2 (spasmolytic protein 1) /FL=gb:NM_005423.1 NM_005423 trefoil factor 2 TFF2 7032 NM_005423 0007586 // digestion // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0043031 // negative regulation of macrophage activation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0060455 // negative regulation of gastric acid secretion // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031723 // CXCR4 chemokine receptor binding // inferred from electronic annotation 214477_at NM_005934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005934.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 1 (MLLT1), mRNA. /FEA=CDS /GEN=MLLT1 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 1 /DB_XREF=gi:5174570 /UG=Hs.234774 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 1 /FL=gb:L04285.1 gb:NM_005934.1 NM_005934 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 MLLT1 4298 NM_005934 /// XM_005259561 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214478_at NM_006944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006944.1 /DEF=Homo sapiens secreted phosphoprotein 2, 24kD (SPP2), mRNA. /FEA=CDS /GEN=SPP2 /PROD=secreted phosphoprotein 2, 24kD /DB_XREF=gi:5902117 /UG=Hs.12230 secreted phosphoprotein 2, 24kD /FL=gb:U20530.1 gb:NM_006944.1 NM_006944 secreted phosphoprotein 2, 24kDa SPP2 6694 NM_006944 /// XM_005246102 0001501 // skeletal system development // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0046849 // bone remodeling // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation 214479_at NM_001496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001496.1 /DEF=Homo sapiens GDNF family receptor alpha 3 (GFRA3), mRNA. /FEA=CDS /GEN=GFRA3 /PROD=GDNF family receptor alpha 3 /DB_XREF=gi:4557622 /UG=Hs.211955 GDNF family receptor alpha 3 /FL=gb:AF051767.1 gb:NM_001496.1 NM_001496 GDNF family receptor alpha 3 GFRA3 2676 NM_001496 0001764 // neuron migration // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007422 // peripheral nervous system development // traceable author statement /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation 214480_at L16464 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L16464.1 /DEF=Human ETS oncogene (PEP1) mRNA, complete cds. /FEA=mRNA /GEN=PEP1 /PROD=ETS oncogene /DB_XREF=gi:291991 /UG=Hs.179214 ets variant gene 3 /FL=gb:L16464.1 L16464 ets variant 3 ETV3 2117 NM_001145312 /// NM_005240 /// XM_006711210 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // not recorded /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214481_at NM_003514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003514.1 /DEF=Homo sapiens H2A histone family, member N (H2AFN), mRNA. /FEA=CDS /GEN=H2AFN /PROD=H2A histone family, member N /DB_XREF=gi:4504248 /UG=Hs.134999 H2A histone family, member N /FL=gb:NM_003514.1 NM_003514 histone cluster 1, H2am HIST1H2AM 8336 NM_003514 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214482_at NM_006977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006977.1 /DEF=Homo sapiens zinc finger protein 46 (KUP) (ZNF46), mRNA. /FEA=CDS /GEN=ZNF46 /PROD=zinc finger protein 46 (KUP) /DB_XREF=gi:5902163 /UG=Hs.164347 zinc finger protein 46 (KUP) /FL=gb:NM_006977.1 NM_006977 zinc finger and BTB domain containing 25 ZBTB25 7597 NM_006977 /// XM_005268049 /// XM_005268051 /// XM_005268052 /// XM_005268053 /// XM_006720250 /// XM_006720251 /// XM_006720252 /// XM_006720253 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010467 // gene expression // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214483_s_at AF124489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF124489.1 /DEF=Homo sapiens arfaptin-1b mRNA, alternatively spliced, complete cds. /FEA=CDS /PROD=arfaptin-1b /DB_XREF=gi:4761515 /UG=Hs.301064 arfaptin 1 /FL=gb:AF124489.1 AF124489 ADP-ribosylation factor interacting protein 1 ARFIP1 27236 NM_001025593 /// NM_001025595 /// NM_001287431 /// NM_001287432 /// NM_001287433 /// NM_014447 0006886 // intracellular protein transport // inferred from direct assay /// 0050708 // regulation of protein secretion // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 214484_s_at AF226604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF226604.1 /DEF=Homo sapiens sigma 1 receptor beta variant mRNA, complete cds, alternatively spliced. /FEA=CDS /PROD=sigma 1 receptor beta variant /DB_XREF=gi:7582319 /UG=Hs.24447 sigma receptor (SR31747 binding protein 1) /FL=gb:AF226604.1 AF226604 sigma non-opioid intracellular receptor 1 SIGMAR1 10280 NM_001282205 /// NM_001282206 /// NM_001282207 /// NM_001282208 /// NM_001282209 /// NM_005866 /// NM_147157 /// NM_147158 /// NM_147159 /// NM_147160 /// NR_104108 0006696 // ergosterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // traceable author statement 214485_at NM_024410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_024410.1 /DEF=Homo sapiens outer dense fibre of sperm tails 1 (ODF1), mRNA. /FEA=CDS /GEN=ODF1 /PROD=outer dense fibre of sperm tails 1 /DB_XREF=gi:13249341 /UG=Hs.159274 outer dense fibre of sperm tails 1 /FL=gb:NM_024410.1 NM_024410 outer dense fiber of sperm tails 1 ODF1 4956 NM_024410 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0001520 // outer dense fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation 214486_x_at AF041459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041459.1 /DEF=Homo sapiens I-FLICE isoform 2 mRNA, complete cds. /FEA=CDS /PROD=I-FLICE isoform 2 /DB_XREF=gi:2827291 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF041459.1 AF041459 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 214487_s_at NM_002886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002886.1 /DEF=Homo sapiens RAP2B, member of RAS oncogene family (RAP2B), mRNA. /FEA=CDS /GEN=RAP2B /PROD=RAP2B, member of RAS oncogene family /DB_XREF=gi:4506416 /UG=Hs.239527 RAP2B, member of RAS oncogene family /FL=gb:NM_002886.1 NM_002886 RAP2A, member of RAS oncogene family /// RAP2B, member of RAS oncogene family RAP2A /// RAP2B 5911 /// 5912 NM_002886 /// NM_021033 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay /// 0061097 // regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 214488_at NM_002886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002886.1 /DEF=Homo sapiens RAP2B, member of RAS oncogene family (RAP2B), mRNA. /FEA=CDS /GEN=RAP2B /PROD=RAP2B, member of RAS oncogene family /DB_XREF=gi:4506416 /UG=Hs.239527 RAP2B, member of RAS oncogene family /FL=gb:NM_002886.1 NM_002886 RAP2B, member of RAS oncogene family RAP2B 5912 NM_002886 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0061097 // regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 214489_at NM_000510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000510.1 /DEF=Homo sapiens follicle stimulating hormone, beta polypeptide (FSHB), mRNA. /FEA=CDS /GEN=FSHB /PROD=follicle stimulating hormone, beta polypeptide /DB_XREF=gi:4503790 /UG=Hs.36975 follicle stimulating hormone, beta polypeptide /FL=gb:NM_000510.1 NM_000510 follicle stimulating hormone, beta polypeptide FSHB 2488 NM_000510 /// NM_001018080 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001541 // ovarian follicle development // non-traceable author statement /// 0006701 // progesterone biosynthetic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from expression pattern /// 0007283 // spermatogenesis // non-traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0016486 // peptide hormone processing // traceable author statement /// 0030335 // positive regulation of cell migration // non-traceable author statement /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016913 // follicle-stimulating hormone activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // non-traceable author statement 214490_at NM_004042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004042.2 /DEF=Homo sapiens arylsulfatase F (ARSF), mRNA. /FEA=CDS /GEN=ARSF /PROD=arylsulfatase F /DB_XREF=gi:6552297 /UG=Hs.101674 arylsulfatase F /FL=gb:NM_004042.2 NM_004042 arylsulfatase F ARSF 416 NM_001201538 /// NM_001201539 /// NM_004042 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214491_at NM_001051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001051.1 /DEF=Homo sapiens somatostatin receptor 3 (SSTR3), mRNA. /FEA=CDS /GEN=SSTR3 /PROD=somatostatin receptor 3 /DB_XREF=gi:4557860 /UG=Hs.225995 somatostatin receptor 3 /FL=gb:NM_001051.1 NM_001051 somatostatin receptor 3 SSTR3 6753 NM_001051 /// NM_001278687 /// XM_005261721 /// XM_006724311 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008628 // hormone-mediated apoptotic signaling pathway // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // traceable author statement /// 0042594 // response to starvation // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214492_at NM_000337 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000337.1 /DEF=Homo sapiens sarcoglycan, delta (35kD dystrophin-associated glycoprotein) (SGCD), mRNA. /FEA=CDS /GEN=SGCD /PROD=sarcoglycan, delta (35kD dystrophin-associatedglycoprotein) /DB_XREF=gi:4506914 /UG=Hs.151899 sarcoglycan, delta (35kD dystrophin-associated glycoprotein) /FL=gb:NM_000337.1 NM_000337 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) SGCD 6444 NM_000337 /// NM_001128209 /// NM_172244 /// XM_005265965 /// XM_005265966 /// XM_005265967 /// XM_006714911 /// XM_006714912 0007517 // muscle organ development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016012 // sarcoglycan complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214493_s_at NM_005799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005799.1 /DEF=Homo sapiens PDZ domain protein (Drosophila inaD-like) (INADL), mRNA. /FEA=CDS /GEN=INADL /PROD=PDZ domain protein (Drosophila inaD-like) /DB_XREF=gi:5031790 /UG=Hs.321197 PDZ domain protein (Drosophila inaD-like) /FL=gb:NM_005799.1 NM_005799 InaD-like (Drosophila) INADL 10207 NM_005799 /// NM_176877 /// NM_176878 /// XM_005270341 /// XM_005270343 /// XM_005270345 /// XM_005270347 /// XM_006710275 /// XM_006710276 /// XM_006710277 /// XM_006710278 0034329 // cell junction assembly // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214494_s_at NM_005200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005200.1 /DEF=Homo sapiens cell matrix adhesion regulator (CMAR), mRNA. /FEA=CDS /GEN=CMAR /PROD=cell matrix adhesion regulator /DB_XREF=gi:4885142 /UG=Hs.272480 cell matrix adhesion regulator /FL=gb:NM_005200.1 NM_005200 uncharacterized LOC101930112 /// spastic paraplegia 7 (pure and complicated autosomal recessive) LOC101930112 /// SPG7 6687 /// 101930112 NM_003119 /// NM_199367 /// XM_005256321 /// XM_006721264 /// XM_006721265 /// XM_006721266 /// XR_253599 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 214495_at NM_006078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006078.1 /DEF=Homo sapiens calcium channel, voltage-dependent, gamma subunit 2 (CACNG2), mRNA. /FEA=CDS /GEN=CACNG2 /PROD=calcium channel, voltage-dependent, gammasubunit 2 /DB_XREF=gi:5174404 /UG=Hs.268545 calcium channel, voltage-dependent, gamma subunit 2 /FL=gb:AF096322.1 gb:NM_006078.1 NM_006078 calcium channel, voltage-dependent, gamma subunit 2 CACNG2 10369 NM_006078 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050877 // neurological system process // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 214496_x_at NM_012330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012330.1 /DEF=Homo sapiens histone acetyltransferase (MORF), mRNA. /FEA=CDS /GEN=MORF /PROD=histone acetyltransferase /DB_XREF=gi:6912511 /UG=Hs.27590 histone acetyltransferase /FL=gb:AF119231.1 gb:NM_012330.1 NM_012330 K(lysine) acetyltransferase 6B KAT6B 23522 NM_001256468 /// NM_001256469 /// NM_012330 /// XM_005269664 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214497_s_at NM_005599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005599.1 /DEF=Homo sapiens nescient helix loop helix 2 (NHLH2), mRNA. /FEA=CDS /GEN=NHLH2 /PROD=nescient helix loop helix 2 /DB_XREF=gi:5031944 /UG=Hs.46296 nescient helix loop helix 2 /FL=gb:NM_005599.1 NM_005599 nescient helix loop helix 2 NHLH2 4808 NM_001111061 /// NM_005599 /// XM_006710666 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 214498_at NM_001672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001672.1 /DEF=Homo sapiens agouti (mouse)-signaling protein (ASIP), mRNA. /FEA=CDS /GEN=ASIP /PROD=agouti (mouse)-signaling protein /DB_XREF=gi:4502254 /UG=Hs.37006 agouti (mouse)-signaling protein /FL=gb:NM_001672.1 NM_001672 agouti signaling protein ASIP 434 NM_001672 /// XM_005260412 0006091 // generation of precursor metabolites and energy // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008343 // adult feeding behavior // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from electronic annotation /// 0040030 // regulation of molecular function, epigenetic // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0031779 // melanocortin receptor binding // inferred from electronic annotation /// 0031781 // type 3 melanocortin receptor binding // inferred from electronic annotation /// 0031782 // type 4 melanocortin receptor binding // inferred from electronic annotation 214499_s_at AF249273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF249273.1 /DEF=Homo sapiens Bcl-2-associated transcription factor short form mRNA, complete cds. /FEA=CDS /PROD=Bcl-2-associated transcription factor shortform /DB_XREF=gi:7582385 /UG=Hs.80338 KIAA0164 gene product /FL=gb:AF249273.1 AF249273 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214500_at AF044286 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF044286.1 /DEF=Homo sapiens histone macroH2A1.1 mRNA, complete cds. /FEA=CDS /PROD=histone macroH2A1.1 /DB_XREF=gi:3493530 /UG=Hs.75258 H2A histone family, member Y /FL=gb:AF044286.1 AF044286 H2A histone family, member Y H2AFY 9555 NM_001040158 /// NM_004893 /// NM_138609 /// NM_138610 /// XM_005272132 /// XM_005272134 /// XM_005272135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001558 // regulation of cell growth // inferred from genetic interaction /// 0006334 // nucleosome assembly // non-traceable author statement /// 0007549 // dosage compensation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from mutant phenotype /// 0045814 // negative regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0061187 // regulation of chromatin silencing at rDNA // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from mutant phenotype /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from genetic interaction /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype /// 1902750 // negative regulation of cell cycle G2/M phase transition // inferred from mutant phenotype 0000786 // nucleosome // non-traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0001739 // sex chromatin // traceable author statement /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000182 // rDNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010385 // double-stranded methylated DNA binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214501_s_at AF044286 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF044286.1 /DEF=Homo sapiens histone macroH2A1.1 mRNA, complete cds. /FEA=CDS /PROD=histone macroH2A1.1 /DB_XREF=gi:3493530 /UG=Hs.75258 H2A histone family, member Y /FL=gb:AF044286.1 AF044286 H2A histone family, member Y H2AFY 9555 NM_001040158 /// NM_004893 /// NM_138609 /// NM_138610 /// XM_005272132 /// XM_005272134 /// XM_005272135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001558 // regulation of cell growth // inferred from genetic interaction /// 0006334 // nucleosome assembly // non-traceable author statement /// 0007549 // dosage compensation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from mutant phenotype /// 0045814 // negative regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0061187 // regulation of chromatin silencing at rDNA // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from mutant phenotype /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from genetic interaction /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype /// 1902750 // negative regulation of cell cycle G2/M phase transition // inferred from mutant phenotype 0000786 // nucleosome // non-traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0001739 // sex chromatin // traceable author statement /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000182 // rDNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010385 // double-stranded methylated DNA binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214502_at NM_021058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021058.1 /DEF=Homo sapiens H2B histone family, member R (H2BFR), mRNA. /FEA=CDS /GEN=H2BFR /PROD=H2B histone family, member R /DB_XREF=gi:10800145 /UG=Hs.285735 H2B histone family, member R /FL=gb:NM_021058.1 NM_021058 histone cluster 1, H2bj HIST1H2BJ 8970 NM_021058 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214503_x_at NM_022571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_022571.1 /DEF=Homo sapiens putative leukocyte platelet-activating factor receptor (HUMNPIIY20), mRNA. /FEA=CDS /GEN=HUMNPIIY20 /PROD=putative leukocyte platelet-activating factorreceptor /DB_XREF=gi:12007653 /UG=Hs.278077 putative leukocyte platelet-activating factor receptor /FL=gb:NM_022571.1 NM_022571 G protein-coupled receptor 135 GPR135 64582 NM_022571 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004992 // platelet activating factor receptor activity // traceable author statement 214504_at NM_020469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_020469.1 /DEF=Homo sapiens ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (ABO), mRNA. /FEA=CDS /GEN=ABO /PROD=ABO blood group (transferase A, alpha1-3-N-acetylgalactosaminyltransferase; transferase B,alpha 1-3-galactosyltransferase) /DB_XREF=gi:9994164 /UG=Hs.113271 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) /FL=gb:J05175.1 gb:AF134412.1 gb:AF134413.1 gb:AF134414.1 gb:NM_020469.1 NM_020469 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) ABO 28 NM_020469 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0004380 // glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0004381 // fucosylgalactoside 3-alpha-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214505_s_at AF220153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF220153.1 /DEF=Homo sapiens four and a half LIM domains 1 protein isoform C (FHL1) mRNA, complete cds, alternatively spliced. /FEA=CDS /GEN=FHL1 /PROD=four and a half LIM domains 1 protein isoform C /DB_XREF=gi:6942192 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:AF220153.1 AF220153 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214506_at NM_007264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007264.2 /DEF=Homo sapiens G-protein coupled receptor similar to the adrenomedullin receptor (ADMR), mRNA. /FEA=CDS /GEN=ADMR /PROD=G-protein coupled receptor similar to theadrenomedullin receptor /DB_XREF=gi:6466448 /UG=Hs.16743 G-protein coupled receptor similar to the adrenomedullin receptor /FL=gb:NM_007264.2 NM_007264 G protein-coupled receptor 182 GPR182 11318 NM_007264 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 214507_s_at NM_014285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014285.1 /DEF=Homo sapiens homolog of Yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease (RRP4), mRNA. /FEA=CDS /GEN=RRP4 /PROD=homolog of Yeast RRP4 (ribosomal RNA processing4), 3-5-exoribonuclease /DB_XREF=gi:7657527 /UG=Hs.211973 homolog of Yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease /FL=gb:NM_014285.1 NM_014285 exosome component 2 EXOSC2 23404 NM_001282708 /// NM_001282709 /// NM_014285 /// NR_104230 /// XM_005272176 /// XM_006717020 /// XM_006717021 /// XM_006717022 /// XM_006717023 /// XM_006717024 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008312 // 7S RNA binding // traceable author statement 214508_x_at U44836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U44836.1 /DEF=Human inducible cAMP early repressor (CREM) mRNA, complete cds. /FEA=CDS /GEN=CREM /PROD=inducible cAMP early repressor /DB_XREF=gi:1177861 /UG=Hs.155924 cAMP responsive element modulator /FL=gb:U44836.1 U44836 cAMP responsive element modulator CREM 1390 NM_001267562 /// NM_001267563 /// NM_001267564 /// NM_001267565 /// NM_001267566 /// NM_001267567 /// NM_001267568 /// NM_001267569 /// NM_001267570 /// NM_001881 /// NM_181571 /// NM_182717 /// NM_182718 /// NM_182719 /// NM_182720 /// NM_182721 /// NM_182722 /// NM_182723 /// NM_182724 /// NM_182725 /// NM_182769 /// NM_182770 /// NM_182771 /// NM_182772 /// NM_182850 /// NM_182853 /// NM_183011 /// NM_183012 /// NM_183013 /// NM_183060 /// NR_051971 /// NR_051972 /// NR_051973 /// NR_051974 /// NR_051975 /// XM_006717378 /// XM_006717379 /// XM_006717380 /// XM_006717381 /// XM_006717382 /// XM_006717383 /// XM_006717384 /// XM_006717385 /// XM_006717386 /// XM_006717387 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008140 // cAMP response element binding protein binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214509_at NM_003533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003533.1 /DEF=Homo sapiens H3 histone family, member F (H3FF), mRNA. /FEA=CDS /GEN=H3FF /PROD=H3 histone family, member F /DB_XREF=gi:4504288 /UG=Hs.132854 H3 histone family, member F /FL=gb:NM_003533.1 NM_003533 histone cluster 1, H3i HIST1H3I 8354 NM_003533 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214510_at NM_005293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005293.1 /DEF=Homo sapiens G protein-coupled receptor 20 (GPR20), mRNA. /FEA=CDS /GEN=GPR20 /PROD=G protein-coupled receptor 20 /DB_XREF=gi:4885304 /UG=Hs.188859 G protein-coupled receptor 20 /FL=gb:NM_005293.1 NM_005293 G protein-coupled receptor 20 GPR20 2843 NM_005293 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay 214511_x_at L03419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L03419.1 /DEF=Human Fc-gamma receptor I B1 mRNA, complete cds. /FEA=CDS /PROD=Fc gamma receptor I /DB_XREF=gi:182460 /UG=Hs.77424 Fc fragment of IgG, high affinity Ia, receptor for (CD64) /FL=gb:L03419.1 gb:L03420.1 L03419 Fc fragment of IgG, high affinity Ib, receptor (CD64) FCGR1B 2210 NM_001004340 /// NM_001017986 /// NM_001244910 /// NR_045213 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006911 // phagocytosis, engulfment // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038093 // Fc receptor signaling pathway // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019763 // immunoglobulin receptor activity // non-traceable author statement /// 0019864 // IgG binding // inferred from electronic annotation 214512_s_at NM_006713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006713.1 /DEF=Homo sapiens activated RNA polymerase II transcription cofactor 4 (PC4), mRNA. /FEA=CDS /GEN=PC4 /PROD=activated RNA polymerase II transcriptioncofactor 4 /DB_XREF=gi:5729967 /UG=Hs.74861 activated RNA polymerase II transcription cofactor 4 /FL=gb:U12979.1 gb:NM_006713.1 NM_006713 SUB1 homolog (S. cerevisiae) SUB1 10923 NM_006713 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214513_s_at M34356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M34356.1 /DEF=Human active transcription factor CREB mRNA, complete cds. /FEA=CDS /DB_XREF=gi:181042 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M34356.1 M34356 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214514_at NM_003906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003906.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 3-associated protein (MCM3AP), mRNA. /FEA=CDS /GEN=MCM3AP /PROD=minichromosome maintenance deficient (S.cerevisiae) 3-associated protein /DB_XREF=gi:4505132 /UG=Hs.168481 minichromosome maintenance deficient (S. cerevisiae) 3-associated protein /FL=gb:AB005543.1 gb:NM_003906.1 NM_003906 minichromosome maintenance complex component 3 associated protein MCM3AP 8888 NM_003906 /// XM_005261203 /// XM_005261204 /// XM_005261205 /// XM_005261206 /// XM_006724064 /// XM_006724065 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 214515_at NM_003553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003553.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily E, member 1 (OR1E1), mRNA. /FEA=CDS /GEN=OR1E1 /PROD=olfactory receptor, family 1, subfamily E,member 1 /DB_XREF=gi:11496274 /UG=Hs.278485 olfactory receptor, family 1, subfamily E, member 1 /FL=gb:NM_003553.1 NM_003553 olfactory receptor, family 1, subfamily E, member 1 OR1E1 8387 NM_003553 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement 214516_at NM_003544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003544.1 /DEF=Homo sapiens H4 histone family, member I (H4FI), mRNA. /FEA=CDS /GEN=H4FI /PROD=H4 histone family, member I /DB_XREF=gi:4504312 /UG=Hs.143080 H4 histone family, member I /FL=gb:NM_003544.1 NM_003544 histone cluster 1, H4a /// histone cluster 1, H4b /// histone cluster 1, H4c /// histone cluster 1, H4d /// histone cluster 1, H4e /// histone cluster 1, H4f /// histone cluster 1, H4h /// histone cluster 1, H4i /// histone cluster 1, H4j /// histone cluster 1, H4k /// histone cluster 1, H4l /// histone cluster 2, H4a /// histone cluster 2, H4b /// histone cluster 4, H4 HIST1H4A /// HIST1H4B /// HIST1H4C /// HIST1H4D /// HIST1H4E /// HIST1H4F /// HIST1H4H /// HIST1H4I /// HIST1H4J /// HIST1H4K /// HIST1H4L /// HIST2H4A /// HIST2H4B /// HIST4H4 8294 /// 8359 /// 8360 /// 8361 /// 8362 /// 8363 /// 8364 /// 8365 /// 8366 /// 8367 /// 8368 /// 8370 /// 121504 /// 554313 NM_001034077 /// NM_003495 /// NM_003538 /// NM_003539 /// NM_003540 /// NM_003541 /// NM_003542 /// NM_003543 /// NM_003544 /// NM_003545 /// NM_003546 /// NM_003548 /// NM_021968 /// NM_175054 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214517_at NM_005553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005553.1 /DEF=Homo sapiens keratin, cuticle, ultrahigh sulphur 1 (KRN1), mRNA. /FEA=CDS /GEN=KRN1 /PROD=keratin, cuticle, ultrahigh sulphur 1 /DB_XREF=gi:5031834 /UG=Hs.2743 keratin, cuticle, ultrahigh sulphur 1 /FL=gb:NM_005553.1 NM_005553 keratin associated protein 5-9 KRTAP5-9 3846 NM_005553 0008544 // epidermis development // traceable author statement 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214518_at NM_005390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005390.1 /DEF=Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 2 (PDHA2), mRNA. /FEA=CDS /GEN=PDHA2 /PROD=pyruvate dehydrogenase (lipoamide) alpha 2 /DB_XREF=gi:4885542 /UG=Hs.131361 pyruvate dehydrogenase (lipoamide) alpha 2 /FL=gb:NM_005390.1 NM_005390 pyruvate dehydrogenase (lipoamide) alpha 2 PDHA2 5161 NM_005390 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation 214519_s_at NM_005059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005059.1 /DEF=Homo sapiens relaxin 2 (H2) (RLN2), mRNA. /FEA=CDS /GEN=RLN2 /PROD=relaxin 2 (H2) /DB_XREF=gi:4826981 /UG=Hs.127032 relaxin 2 (H2) /FL=gb:NM_005059.1 NM_005059 relaxin 2 RLN2 6019 NM_005059 /// NM_134441 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 214520_at NM_005251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005251.1 /DEF=Homo sapiens forkhead box C2 (MFH-1, mesenchyme forkhead 1) (FOXC2), mRNA. /FEA=CDS /GEN=FOXC2 /PROD=forkhead box C2 /DB_XREF=gi:4885236 /UG=Hs.239571 forkhead box C2 (MFH-1, mesenchyme forkhead 1) /FL=gb:NM_005251.1 NM_005251 forkhead box C2 (MFH-1, mesenchyme forkhead 1) FOXC2 2303 NM_005251 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // not recorded /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001656 // metanephros development // not recorded /// 0001657 // ureteric bud development // not recorded /// 0001756 // somitogenesis // not recorded /// 0001822 // kidney development // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0001946 // lymphangiogenesis // inferred from mutant phenotype /// 0001974 // blood vessel remodeling // not recorded /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // non-traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009725 // response to hormone // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from sequence or structural similarity /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0030199 // collagen fibril organization // not recorded /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035050 // embryonic heart tube development // not recorded /// 0035470 // positive regulation of vascular wound healing // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // not recorded /// 0043066 // negative regulation of apoptotic process // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046620 // regulation of organ growth // not recorded /// 0048010 // vascular endothelial growth factor receptor signaling pathway // not recorded /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048343 // paraxial mesodermal cell fate commitment // not recorded /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // not recorded /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048844 // artery morphogenesis // not recorded /// 0050880 // regulation of blood vessel size // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0055010 // ventricular cardiac muscle tissue morphogenesis // not recorded /// 0060038 // cardiac muscle cell proliferation // not recorded /// 0072011 // glomerular endothelium development // inferred from electronic annotation /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from electronic annotation /// 0072144 // glomerular mesangial cell development // inferred from electronic annotation /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 1902257 // negative regulation of apoptotic process involved in outflow tract morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 214521_at NM_019089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_019089.1 /DEF=Homo sapiens hairy and enhancer of split (Drosophila) homolog 2 (HES2), mRNA. /FEA=CDS /GEN=HES2 /PROD=hairy and enhancer of split (Drosophila) homolog2 /DB_XREF=gi:10092644 /UG=Hs.156042 hairy and enhancer of split (Drosophila) homolog 2 /FL=gb:NM_019089.1 NM_019089 hes family bHLH transcription factor 2 HES2 54626 NM_019089 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0008134 // transcription factor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 214522_x_at NM_021065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021065.1 /DEF=Homo sapiens H2A histone family, member G (H2AFG), mRNA. /FEA=CDS /GEN=H2AFG /PROD=H2A histone family, member G /DB_XREF=gi:10800129 /UG=Hs.239458 H2A histone family, member G /FL=gb:NM_021065.1 NM_021065 histone cluster 1, H2ad /// histone cluster 1, H3d HIST1H2AD /// HIST1H3D 3013 /// 8351 NM_003530 /// NM_021065 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214523_at NM_001805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001805.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), epsilon (CEBPE), mRNA. /FEA=CDS /GEN=CEBPE /PROD=CCAATenhancer binding protein (CEBP), epsilon /DB_XREF=gi:4502766 /UG=Hs.158323 CCAATenhancer binding protein (CEBP), epsilon /FL=gb:NM_001805.1 NM_001805 CCAAT/enhancer binding protein (C/EBP), epsilon CEBPE 1053 NM_001805 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // inferred from electronic annotation /// 0042089 // cytokine biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214524_at NM_021081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021081.1 /DEF=Homo sapiens growth hormone releasing hormone (GHRH), mRNA. /FEA=CDS /GEN=GHRH /PROD=growth hormone releasing hormone /DB_XREF=gi:11034840 /UG=Hs.37023 growth hormone releasing hormone /FL=gb:NM_021081.1 NM_021081 growth hormone releasing hormone GHRH 2691 NM_001184731 /// NM_021081 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred by curator /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0021984 // adenohypophysis development // inferred from sequence or structural similarity /// 0030252 // growth hormone secretion // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032094 // response to food // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // non-traceable author statement /// 0046005 // positive regulation of circadian sleep/wake cycle, REM sleep // inferred from mutant phenotype /// 0046005 // positive regulation of circadian sleep/wake cycle, REM sleep // non-traceable author statement /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from direct assay /// 0060124 // positive regulation of growth hormone secretion // inferred from mutant phenotype /// 0060124 // positive regulation of growth hormone secretion // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016608 // growth hormone-releasing hormone activity // inferred from direct assay /// 0031770 // growth hormone-releasing hormone receptor binding // inferred from physical interaction 214525_x_at AB039667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB039667.1 /DEF=Homo sapiens mRNA for DNA mismatch repair protein MLH3, complete cds. /FEA=CDS /GEN=MLH3 /PROD=DNA mismatch repair protein MLH3 /DB_XREF=gi:7209865 /UG=Hs.279843 mutL (E. coli) homolog 3 /FL=gb:AB039667.1 AB039667 mutL homolog 3 MLH3 27030 NM_001040108 /// NM_014381 /// XM_005267531 /// XM_005267532 /// XM_005267533 /// XM_005267534 /// XM_006720116 /// XM_006720117 /// XR_245681 /// XR_429311 /// XR_429312 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // non-traceable author statement /// 0007140 // male meiosis // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005712 // chiasma // not recorded /// 0032300 // mismatch repair complex // not recorded /// 0032390 // MutLbeta complex // 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // 214526_x_at NM_005394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005394.1 /DEF=Homo sapiens postmeiotic segregation increased 2-like 8 (PMS2L8), mRNA. /FEA=CDS /GEN=PMS2L8 /PROD=postmeiotic segregation increased 2-like 8 /DB_XREF=gi:4885550 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 /FL=gb:NM_005394.1 NM_005394 postmeiotic segregation increased 2 pseudogene 1 PMS2P1 5379 NM_005394 /// NR_003613 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 214527_s_at AB041836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB041836.1 /DEF=Homo sapiens mRNA for PQBP-1d, complete cds. /FEA=CDS /PROD=PQBP-1d /DB_XREF=gi:10801593 /UG=Hs.30570 polyglutamine binding protein 1 /FL=gb:AB041836.1 AB041836 polyglutamine binding protein 1 PQBP1 10084 NM_001032381 /// NM_001032382 /// NM_001032383 /// NM_001032384 /// NM_001032385 /// NM_001167989 /// NM_001167990 /// NM_001167992 /// NM_005710 /// NM_144494 /// NM_144495 /// XM_005272571 /// XM_005272572 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034063 // stress granule assembly // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 214528_s_at NM_013951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_013951.1 /DEF=Homo sapiens paired box gene 8 (PAX8), transcript variant PAX8B, mRNA. /FEA=CDS /GEN=PAX8 /PROD=paired box gene 8, isoform PAX8B /DB_XREF=gi:7524360 /UG=Hs.73149 paired box gene 8 /FL=gb:NM_013951.1 NM_013951 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 214529_at NM_000549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000549.1 /DEF=Homo sapiens thyroid stimulating hormone, beta (TSHB), mRNA. /FEA=CDS /GEN=TSHB /PROD=thyroid stimulating hormone, beta /DB_XREF=gi:4507698 /UG=Hs.53213 thyroid stimulating hormone, beta /FL=gb:NM_000549.1 NM_000549 thyroid stimulating hormone, beta TSHB 7252 NM_000549 /// NM_001277991 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016486 // peptide hormone processing // traceable author statement /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 214530_x_at AF156225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF156225.1 /DEF=Homo sapiens protein 4.1 (EPB4.1) mRNA, complete cds. /FEA=CDS /GEN=EPB4.1 /PROD=protein 4.1 /DB_XREF=gi:5353737 /UG=Hs.37427 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) /FL=gb:AF156225.1 AF156225 erythrocyte membrane protein band 4.1 EPB41 2035 NM_001166005 /// NM_001166006 /// NM_001166007 /// NM_004437 /// NM_203342 /// NM_203343 /// XM_005245753 /// XM_005245757 /// XM_005245760 /// XM_005245761 /// XM_005245763 /// XM_005245764 /// XM_005245765 /// XM_005245767 /// XM_005245768 /// XM_005245769 /// XM_005245770 /// XM_005245772 /// XM_005245773 /// XM_005245774 /// XM_006710434 /// XM_006710435 /// XM_006710436 /// XM_006710437 /// XM_006710438 /// XM_006710439 /// XM_006710440 0008015 // blood circulation // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0014731 // spectrin-associated cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // traceable author statement 214531_s_at AF065484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF065484.1 /DEF=Homo sapiens sorting nexin 1A (SNX1) mRNA, complete cds. /FEA=CDS /GEN=SNX1 /PROD=sorting nexin 1A /DB_XREF=gi:3152941 /UG=Hs.75283 sorting nexin 1 /FL=gb:AF065484.1 AF065484 sorting nexin 1 SNX1 6642 NM_001242933 /// NM_003099 /// NM_148955 /// NM_152826 /// XM_005254610 /// XM_005254611 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 214532_x_at AF268615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF268615.1 /DEF=Homo sapiens POU 5 domain protein (POU5FLC8) mRNA, complete cds. /FEA=CDS /GEN=POU5FLC8 /PROD=POU 5 domain protein /DB_XREF=gi:12382248 /UG=Hs.2860 POU domain, class 5, transcription factor 1 /FL=gb:AF268615.1 gb:AF268618.1 AF268615 POU class 5 homeobox 1B POU5F1B 5462 NM_001159542 /// NR_002304 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214533_at NM_001836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001836.1 /DEF=Homo sapiens chymase 1, mast cell (CMA1), mRNA. /FEA=CDS /GEN=CMA1 /PROD=chymase 1, mast cell /DB_XREF=gi:4502906 /UG=Hs.135626 chymase 1, mast cell /FL=gb:M69136.1 gb:NM_001836.1 NM_001836 chymase 1, mast cell CMA1 1215 NM_001836 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0006518 // peptide metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0050720 // interleukin-1 beta biosynthetic process // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred by curator /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0030141 // secretory granule // not recorded /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 214534_at NM_005322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005322.1 /DEF=Homo sapiens H1 histone family, member 5 (H1F5), mRNA. /FEA=CDS /GEN=H1F5 /PROD=H1 histone family, member 5 /DB_XREF=gi:4885380 /UG=Hs.131956 H1 histone family, member 5 /FL=gb:NM_005322.1 NM_005322 histone cluster 1, H1b HIST1H1B 3009 NM_005322 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006325 // chromatin organization // inferred from mutant phenotype /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0031490 // chromatin DNA binding // inferred from mutant phenotype /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214535_s_at NM_021599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021599.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 2, mRNA. /FEA=CDS /GEN=ADAMTS2 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-2, isoform 2 /DB_XREF=gi:11038658 /UG=Hs.120330 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 /FL=gb:NM_021599.1 NM_021599 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ADAMTS2 9509 NM_014244 /// NM_021599 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214536_at NM_020427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_020427.1 /DEF=Homo sapiens ARS component B (ARS), mRNA. /FEA=CDS /GEN=ARS /PROD=ARS component B /DB_XREF=gi:9966906 /UG=Hs.103505 ARS component B /FL=gb:NM_020427.1 NM_020427 secreted LY6/PLAUR domain containing 1 SLURP1 57152 NM_020427 0001775 // cell activation // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // non-traceable author statement 214537_at NM_005320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005320.1 /DEF=Homo sapiens H1 histone family, member 3 (H1F3), mRNA. /FEA=CDS /GEN=H1F3 /PROD=H1 histone family, member 3 /DB_XREF=gi:4885376 /UG=Hs.136857 H1 histone family, member 3 /FL=gb:NM_005320.1 NM_005320 histone cluster 1, H1d HIST1H1D 3007 NM_005320 0006334 // nucleosome assembly // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 214538_x_at AF073921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF073921.1 /DEF=Homo sapiens regulator of G-protein signaling 6 variant form (RGS6) mRNA, complete cds. /FEA=CDS /GEN=RGS6 /PROD=regulator of G-protein signaling 6 variant form /DB_XREF=gi:3309253 /UG=Hs.3221 regulator of G-protein signalling 6 /FL=gb:AF073921.1 AF073921 regulator of G-protein signaling 6 RGS6 9628 NM_001204416 /// NM_001204417 /// NM_001204418 /// NM_001204419 /// NM_001204420 /// NM_001204421 /// NM_001204422 /// NM_001204423 /// NM_001204424 /// NM_004296 /// XM_005268234 /// XM_005268235 /// XM_005268236 /// XM_006720327 /// XM_006720328 /// XM_006720329 /// XM_006720330 /// XM_006720331 /// XM_006720332 /// XM_006720333 /// XR_429335 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 214539_at NM_005024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005024.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10 (SERPINB10), mRNA. /FEA=CDS /GEN=SERPINB10 /PROD=serine (or cysteine) proteinase inhibitor, cladeB (ovalbumin), member 10 /DB_XREF=gi:4826901 /UG=Hs.158339 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10 /FL=gb:U35459.1 gb:NM_005024.1 NM_005024 serpin peptidase inhibitor, clade B (ovalbumin), member 10 SERPINB10 5273 NM_005024 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 214540_at NM_003527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003527.2 /DEF=Homo sapiens H2B histone family, member N (H2BFN), mRNA. /FEA=CDS /GEN=H2BFN /PROD=H2B histone family, member N /DB_XREF=gi:5870894 /UG=Hs.151506 H2B histone family, member N /FL=gb:NM_003527.2 NM_003527 histone cluster 1, H2bo HIST1H2BO 8348 NM_003527 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement 0000786 // nucleosome // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214541_s_at AF142418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF142418.1 /DEF=Homo sapiens QUAKING isoform 2 (QUAKING) mRNA, complete cds. /FEA=CDS /GEN=QUAKING /PROD=QUAKING isoform 2 /DB_XREF=gi:7542348 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142418.1 AF142418 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214542_x_at NM_003509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003509.1 /DEF=Homo sapiens H2A histone family, member C (H2AFC), mRNA. /FEA=CDS /GEN=H2AFC /PROD=H2A histone family, member C /DB_XREF=gi:4504238 /UG=Hs.137592 H2A histone family, member C /FL=gb:NM_003509.1 NM_003509 histone cluster 1, H2ag /// histone cluster 1, H2ah /// histone cluster 1, H2ai /// histone cluster 1, H2ak /// histone cluster 1, H2al /// histone cluster 1, H2am HIST1H2AG /// HIST1H2AH /// HIST1H2AI /// HIST1H2AK /// HIST1H2AL /// HIST1H2AM 8329 /// 8330 /// 8332 /// 8336 /// 8969 /// 85235 NM_003509 /// NM_003510 /// NM_003511 /// NM_003514 /// NM_021064 /// NM_080596 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214543_x_at AF142421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF142421.1 /DEF=Homo sapiens QUAKING isoform 5 (QUAKING) mRNA, complete cds. /FEA=CDS /GEN=QUAKING /PROD=QUAKING isoform 5 /DB_XREF=gi:7542354 /UG=Hs.15020 homolog of mouse quaking QKI (KH domain RNA binding protein) /FL=gb:AF142420.1 gb:AF142421.1 AF142421 QKI, KH domain containing, RNA binding QKI 9444 NM_006775 /// NM_206853 /// NM_206854 /// NM_206855 /// XM_005267224 /// XR_245557 /// XR_427977 /// XR_427978 0001570 // vasculogenesis // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214544_s_at NM_003825 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003825.1 /DEF=Homo sapiens synaptosomal-associated protein, 23kD (SNAP23), mRNA. /FEA=CDS /GEN=SNAP23 /PROD=synaptosomal-associated protein, 23kD /DB_XREF=gi:4507096 /UG=Hs.184376 synaptosomal-associated protein, 23kD /FL=gb:Y09568.1 gb:NM_003825.1 NM_003825 synaptosomal-associated protein, 23kDa SNAP23 8773 NM_003825 /// NM_130798 /// XM_006720725 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214545_s_at NM_007198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007198.1 /DEF=Homo sapiens proline synthetase co-transcribed (bacterial homolog) (PROSC), mRNA. /FEA=CDS /GEN=PROSC /PROD=proline synthetase co-transcribed (bacterialhomolog) /DB_XREF=gi:6005841 /UG=Hs.301959 proline synthetase co-transcribed (bacterial homolog) /FL=gb:NM_007198.1 NM_007198 proline synthetase co-transcribed homolog (bacterial) PROSC 11212 NM_007198 /// XM_005273395 1901605 // alpha-amino acid metabolic process // not recorded 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0030170 // pyridoxal phosphate binding // not recorded 214546_s_at NM_002566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002566.1 /DEF=Homo sapiens purinergic receptor P2Y, G-protein coupled, 11 (P2RY11), mRNA. /FEA=CDS /GEN=P2RY11 /PROD=purinergic receptor P2Y, G-protein coupled, 11 /DB_XREF=gi:4505554 /UG=Hs.166168 purinergic receptor P2Y, G-protein coupled, 11 /FL=gb:AF030335.1 gb:NM_002566.1 NM_002566 purinergic receptor P2Y, G-protein coupled, 11 /// PPAN-P2RY11 readthrough P2RY11 /// PPAN-P2RY11 5032 /// 692312 NM_001040664 /// NM_001198690 /// NM_002566 0001973 // adenosine receptor signaling pathway // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0023041 // neuronal signal transduction // inferred from direct assay /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0071318 // cellular response to ATP // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0030594 // neurotransmitter receptor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation /// 0045031 // ATP-activated nucleotide receptor activity // inferred from direct assay 214547_at NM_018417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_018417.1 /DEF=Homo sapiens soluble adenylyl cyclase (SAC), mRNA. /FEA=CDS /GEN=SAC /PROD=soluble adenylyl cyclase /DB_XREF=gi:8923843 /UG=Hs.163045 soluble adenylyl cyclase /FL=gb:NM_018673.1 gb:AF176813.1 gb:AF271058.1 gb:NM_018417.1 NM_018417 adenylate cyclase 10 (soluble) ADCY10 55811 NM_001167749 /// NM_018417 /// XM_005245329 /// XM_005245330 /// XM_006711449 0006171 // cAMP biosynthetic process // non-traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 214548_x_at AF064092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF064092.1 /DEF=Homo sapiens mutant guanine nucleotide-binding protein G(s), alpha subunit mRNA, complete cds. /FEA=CDS /PROD=mutant guanine nucleotide-binding protein G(s),alpha subunit /DB_XREF=gi:3142636 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 /FL=gb:AF064092.1 AF064092 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 214549_x_at NM_005987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005987.1 /DEF=Homo sapiens small proline-rich protein 1A (SPRR1A), mRNA. /FEA=CDS /GEN=SPRR1A /PROD=small proline-rich protein 1A /DB_XREF=gi:10835235 /UG=Hs.211913 small proline-rich protein 1A /FL=gb:NM_005987.1 NM_005987 small proline-rich protein 1A SPRR1A 6698 NM_001199828 /// NM_005987 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay 214550_s_at AF145029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF145029.1 /DEF=Homo sapiens transportin-SR (TRN-SR) mRNA, complete cds. /FEA=CDS /GEN=TRN-SR /PROD=transportin-SR /DB_XREF=gi:5052413 /UG=Hs.69235 transportin-SR /FL=gb:AF145029.1 AF145029 transportin 3 TNPO3 23534 NM_001191028 /// NM_012470 /// NR_034053 /// XM_006715911 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035048 // splicing factor protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214551_s_at NM_006137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006137.2 /DEF=Homo sapiens CD7 antigen (p41) (CD7), mRNA. /FEA=CDS /GEN=CD7 /PROD=CD7 antigen (p41) /DB_XREF=gi:7382452 /UG=Hs.36972 CD7 antigen (p41) /FL=gb:NM_006137.2 NM_006137 CD7 molecule CD7 924 NM_006137 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214552_s_at AF098638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF098638.1 /DEF=Homo sapiens rabaptin-4 mRNA, complete cds. /FEA=CDS /PROD=rabaptin-4 /DB_XREF=gi:3832515 /UG=Hs.326056 rabaptin-5 /FL=gb:AF098638.1 AF098638 rabaptin, RAB GTPase binding effector protein 1 RABEP1 9135 NM_001083585 /// NM_001291581 /// NM_001291582 /// NM_004703 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 214553_s_at NM_006628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006628.1 /DEF=Homo sapiens cyclic AMP phosphoprotein, 19 kD (ARPP-19), mRNA. /FEA=CDS /GEN=ARPP-19 /PROD=cyclic AMP phosphoprotein, 19 kD /DB_XREF=gi:5729731 /UG=Hs.7351 cyclic AMP phosphoprotein, 19 kD /FL=gb:NM_006628.1 NM_006628 cAMP-regulated phosphoprotein, 19kDa ARPP19 10776 NM_006628 /// XM_005254132 /// XM_005254133 /// XM_005254134 /// XM_005254135 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from direct assay /// 0046326 // positive regulation of glucose import // non-traceable author statement /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 214554_at NM_003511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003511.1 /DEF=Homo sapiens H2A histone family, member I (H2AFI), mRNA. /FEA=CDS /GEN=H2AFI /PROD=H2A histone family, member I /DB_XREF=gi:4504242 /UG=Hs.233568 H2A histone family, member I /FL=gb:NM_003511.1 NM_003511 histone cluster 1, H2al HIST1H2AL 8332 NM_003511 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214555_at NM_001053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001053.1 /DEF=Homo sapiens somatostatin receptor 5 (SSTR5), mRNA. /FEA=CDS /GEN=SSTR5 /PROD=somatostatin receptor 5 /DB_XREF=gi:4557864 /UG=Hs.241375 somatostatin receptor 5 /FL=gb:NM_001053.1 NM_001053 somatostatin receptor 5 SSTR5 6755 NM_001053 /// NM_001172560 /// NM_001172572 /// NM_001172573 /// XM_006720936 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214556_at NM_001052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001052.1 /DEF=Homo sapiens somatostatin receptor 4 (SSTR4), mRNA. /FEA=CDS /GEN=SSTR4 /PROD=somatostatin receptor 4 /DB_XREF=gi:4557862 /UG=Hs.226015 somatostatin receptor 4 /FL=gb:NM_001052.1 NM_001052 somatostatin receptor 4 SSTR4 6754 NM_001052 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // inferred from electronic annotation /// 0030815 // negative regulation of cAMP metabolic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from electronic annotation 214557_at NM_006607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_006607.1 /DEF=Homo sapiens pituitary tumor-transforming 2 (PTTG2), mRNA. /FEA=CDS /GEN=PTTG2 /PROD=pituitary tumor-transforming 2 /DB_XREF=gi:10835092 /UG=Hs.211506 pituitary tumor-transforming 2 /FL=gb:NM_006607.1 gb:AF095288.1 NM_006607 pituitary tumor-transforming 2 PTTG2 10744 NM_006607 0006259 // DNA metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0017124 // SH3 domain binding // inferred from electronic annotation 214558_at NM_005288 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005288.1 /DEF=Homo sapiens G protein-coupled receptor 12 (GPR12), mRNA. /FEA=CDS /GEN=GPR12 /PROD=G protein-coupled receptor 12 /DB_XREF=gi:4885294 /UG=Hs.123034 G protein-coupled receptor 12 /FL=gb:NM_005288.1 NM_005288 G protein-coupled receptor 12 GPR12 2835 NM_005288 /// XM_005266360 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from electronic annotation 214559_at NM_000796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000796.1 /DEF=Homo sapiens dopamine receptor D3 (DRD3), mRNA. /FEA=CDS /GEN=DRD3 /PROD=dopamine receptor D3 /DB_XREF=gi:4503386 /UG=Hs.121478 dopamine receptor D3 /FL=gb:NM_000796.1 gb:U32499.1 NM_000796 dopamine receptor D3 DRD3 1814 NM_000796 /// NM_001282563 /// NM_001290809 /// NM_033658 /// NM_033659 /// NM_033660 /// NM_033663 /// XM_005247171 /// XM_006713522 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002016 // regulation of blood volume by renin-angiotensin // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007611 // learning or memory // non-traceable author statement /// 0007612 // learning // non-traceable author statement /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0032416 // negative regulation of sodium:proton antiporter activity // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034776 // response to histamine // inferred from direct assay /// 0035176 // social behavior // non-traceable author statement /// 0035483 // gastric emptying // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from expression pattern /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046717 // acid secretion // inferred from sequence or structural similarity /// 0048148 // behavioral response to cocaine // inferred from expression pattern /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from sequence or structural similarity /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from mutant phenotype /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0035240 // dopamine binding // inferred from electronic annotation 214560_at NM_002030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002030.2 /DEF=Homo sapiens formyl peptide receptor-like 2 (FPRL2), mRNA. /FEA=CDS /GEN=FPRL2 /PROD=formyl peptide receptor-like 2 /DB_XREF=gi:4758401 /UG=Hs.158314 formyl peptide receptor-like 2 /FL=gb:M76673.1 gb:NM_002030.2 NM_002030 formyl peptide receptor 3 FPR3 2359 NM_002030 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 214561_at NM_024317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_024317.1 /DEF=Homo sapiens immunoglobulin-like transcript 10 (ILT10), mRNA. /FEA=CDS /GEN=ILT10 /PROD=immunoglobulin-like transcript 10 /DB_XREF=gi:13399319 /UG=Hs.202680 immunoglobulin-like transcript 10 /FL=gb:NM_024317.1 NM_024317 leukocyte immunoglobulin-like receptor pseudogene 2 LILRP2 79166 NR_003061 214562_at NM_003546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003546.1 /DEF=Homo sapiens H4 histone family, member K (H4FK), mRNA. /FEA=CDS /GEN=H4FK /PROD=H4 histone family, member K /DB_XREF=gi:4504316 /UG=Hs.131957 H4 histone family, member K /FL=gb:NM_003546.1 NM_003546 histone cluster 1, H4l HIST1H4L 8368 NM_003546 0000278 // mitotic cell cycle // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0035574 // histone H4-K20 demethylation // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0035575 // histone demethylase activity (H4-K20 specific) // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214563_at AF152524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152524.1 /DEF=Homo sapiens protocadherin gamma C3 short form protein (PCDH-gamma-C3) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-C3 /PROD=protocadherin gamma C3 short form protein /DB_XREF=gi:5457095 /UG=Hs.173310 protocadherin gamma subfamily C, 3 /FL=gb:AF152524.1 AF152524 protocadherin gamma subfamily C, 3 PCDHGC3 5098 NM_002588 /// NM_032402 /// NM_032403 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214564_s_at AF152524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152524.1 /DEF=Homo sapiens protocadherin gamma C3 short form protein (PCDH-gamma-C3) variable region sequence, complete cds. /FEA=CDS /GEN=PCDH-gamma-C3 /PROD=protocadherin gamma C3 short form protein /DB_XREF=gi:5457095 /UG=Hs.173310 protocadherin gamma subfamily C, 3 /FL=gb:AF152524.1 AF152524 protocadherin gamma subfamily C, 3 PCDHGC3 5098 NM_002588 /// NM_032402 /// NM_032403 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214565_s_at NM_012390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012390.1 /DEF=Homo sapiens protein homologous to salivary proline-rich protein P-B (PBI), mRNA. /FEA=CDS /GEN=PBI /PROD=protein homologous to salivary proline-richprotein P-B /DB_XREF=gi:6912577 /UG=Hs.166099 protein homologous to salivary proline-rich protein P-B /FL=gb:NM_012390.1 NM_012390 submaxillary gland androgen regulated protein 3A /// submaxillary gland androgen regulated protein 3B SMR3A /// SMR3B 10879 /// 26952 NM_006685 /// NM_012390 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 214566_at NM_012390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012390.1 /DEF=Homo sapiens protein homologous to salivary proline-rich protein P-B (PBI), mRNA. /FEA=CDS /GEN=PBI /PROD=protein homologous to salivary proline-richprotein P-B /DB_XREF=gi:6912577 /UG=Hs.166099 protein homologous to salivary proline-rich protein P-B /FL=gb:NM_012390.1 NM_012390 submaxillary gland androgen regulated protein 3A SMR3A 26952 NM_012390 0005576 // extracellular region // inferred from electronic annotation 214567_s_at NM_003175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003175.1 /DEF=Homo sapiens small inducible cytokine subfamily C, member 2 (SCYC2), mRNA. /FEA=CDS /GEN=SCYC2 /PROD=small inducible cytokine subfamily C, member 2 /DB_XREF=gi:4506854 /UG=Hs.174228 small inducible cytokine subfamily C, member 2 /FL=gb:NM_003175.1 NM_003175 chemokine (C motif) ligand 1 /// chemokine (C motif) ligand 2 XCL1 /// XCL2 6375 /// 6846 NM_002995 /// NM_003175 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from sequence or structural similarity /// 0002725 // negative regulation of T cell cytokine production // inferred from direct assay /// 0002726 // positive regulation of T cell cytokine production // inferred from sequence or structural similarity /// 0002826 // negative regulation of T-helper 1 type immune response // inferred by curator /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred by curator /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0008015 // blood circulation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0035782 // mature natural killer cell chemotaxis // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from sequence or structural similarity /// 0071636 // positive regulation of transforming growth factor beta production // inferred from direct assay /// 0071663 // positive regulation of granzyme B production // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity /// 2000412 // positive regulation of thymocyte migration // inferred from sequence or structural similarity /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay /// 2000513 // positive regulation of granzyme A production // inferred from direct assay /// 2000518 // negative regulation of T-helper 1 cell activation // inferred from direct assay /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity /// 2000556 // positive regulation of T-helper 1 cell cytokine production // inferred from sequence or structural similarity /// 2000558 // positive regulation of immunoglobulin production in mucosal tissue // inferred from sequence or structural similarity /// 2000562 // negative regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from sequence or structural similarity /// 2000566 // positive regulation of CD8-positive, alpha-beta T cell proliferation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from direct assay /// 0042379 // chemokine receptor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 214568_at NM_012217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_012217.1 /DEF=Homo sapiens mast cell tryptase (TPSD1), mRNA. /FEA=CDS /GEN=TPSD1 /PROD=mast cell tryptase /DB_XREF=gi:11321635 /UG=Hs.241387 tryptase delta 1 /FL=gb:NM_012217.1 NM_012217 tryptase delta 1 TPSD1 23430 NM_012217 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 214569_at NM_002169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002169.1 /DEF=Homo sapiens interferon, alpha 5 (IFNA5), mRNA. /FEA=CDS /GEN=IFNA5 /PROD=interferon, alpha 5 /DB_XREF=gi:4504596 /UG=Hs.37113 interferon, alpha 5 /FL=gb:NM_002169.1 NM_002169 interferon, alpha 5 IFNA5 3442 NM_002169 0002250 // adaptive immune response // not recorded /// 0002286 // T cell activation involved in immune response // not recorded /// 0002323 // natural killer cell activation involved in immune response // not recorded /// 0006952 // defense response // inferred from electronic annotation /// 0006959 // humoral immune response // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // not recorded /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // not recorded /// 0033141 // positive regulation of peptidyl-serine phosphorylation of STAT protein // not recorded /// 0042100 // B cell proliferation // not recorded /// 0043330 // response to exogenous dsRNA // not recorded /// 0045087 // innate immune response // not recorded /// 0045087 // innate immune response // traceable author statement /// 0045343 // regulation of MHC class I biosynthetic process // not recorded /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded 0005125 // cytokine activity // not recorded /// 0005126 // cytokine receptor binding // traceable author statement /// 0005132 // type I interferon receptor binding // not recorded 214570_x_at NM_014348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014348.1 /DEF=Homo sapiens similar to rat integral membrane glycoprotein POM121 (POM121L1), mRNA. /FEA=CDS /GEN=POM121L1 /PROD=similar to rat integral membrane glycoproteinPOM121 /DB_XREF=gi:7657468 /UG=Hs.296429 similar to rat integral membrane glycoprotein POM121 /FL=gb:NM_014348.1 NM_014348 uncharacterized LOC102725072 /// putative POM121-like protein 1-like /// putative POM121-like protein 1-like /// POM121 transmembrane nucleoporin-like 10, pseudogene /// POM121 transmembrane nucleoporin-like 1, pseudogene /// POM121 transmembrane nucleoporin-like 4 pseudogene /// POM121 transmembrane nucleoporin-like 8 pseudogene /// POM121 transmembrane nucleoporin-like 9, pseudogene LOC102725072 /// LOC102725315 /// LOC727983 /// POM121L10P /// POM121L1P /// POM121L4P /// POM121L8P /// POM121L9P 25812 /// 29774 /// 29797 /// 266697 /// 646074 /// 727983 /// 102725072 /// 102725315 NM_001025230 /// NM_001029950 /// NM_014549 /// NR_003714 /// NR_024583 /// NR_024591 /// NR_024592 /// NR_024593 /// XM_006710119 /// XR_158956 /// XR_172360 /// XR_433674 /// XR_433675 /// XR_433676 /// XR_433677 214571_at NM_005247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005247.1 /DEF=Homo sapiens fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) (FGF3), mRNA. /FEA=CDS /GEN=FGF3 /PROD=fibroblast growth factor 3 (murine mammary tumorvirus integration site (v-int-2) oncogene homolog) /DB_XREF=gi:4885232 /UG=Hs.37092 fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) /FL=gb:NM_005247.1 NM_005247 fibroblast growth factor 3 FGF3 2248 NM_005247 0001759 // organ induction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048538 // thymus development // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055026 // negative regulation of cardiac muscle tissue development // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 214572_s_at NM_005543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005543.1 /DEF=Homo sapiens insulin-like 3 (Leydig cell) (INSL3), mRNA. /FEA=CDS /GEN=INSL3 /PROD=insulin-like 3 (Leydig cell) /DB_XREF=gi:5031802 /UG=Hs.37062 insulin-like 3 (Leydig cell) /FL=gb:NM_005543.1 NM_005543 insulin-like 3 (Leydig cell) INSL3 3640 NM_001265587 /// NM_005543 0001556 // oocyte maturation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0005102 // receptor binding // traceable author statement /// 0005158 // insulin receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 214574_x_at NM_007161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007161.1 /DEF=Homo sapiens DNA segment on chromosome 6 (unique) 49 expressed sequence, NK cell triggering receptor, p30 (D6S49E), mRNA. /FEA=CDS /GEN=D6S49E /PROD=leukocyte-specific transcript 1 /DB_XREF=gi:6005740 /UG=Hs.88411 lymphocyte antigen 117 /FL=gb:NM_007161.1 NM_007161 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 214575_s_at NM_001700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001700.1 /DEF=Homo sapiens azurocidin 1 (cationic antimicrobial protein 37) (AZU1), mRNA. /FEA=CDS /GEN=AZU1 /PROD=azurocidin 1 (cationic antimicrobial protein37) /DB_XREF=gi:11342669 /UG=Hs.72885 azurocidin 1 (cationic antimicrobial protein 37) /FL=gb:NM_001700.1 NM_001700 azurocidin 1 AZU1 566 NM_001700 0001774 // microglial cell activation // inferred from expression pattern /// 0006508 // proteolysis // not recorded /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0042117 // monocyte activation // traceable author statement /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043114 // regulation of vascular permeability // non-traceable author statement /// 0045123 // cellular extravasation // non-traceable author statement /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from expression pattern /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048246 // macrophage chemotaxis // non-traceable author statement /// 0050725 // positive regulation of interleukin-1 beta biosynthetic process // inferred from direct assay /// 0050754 // positive regulation of fractalkine biosynthetic process // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // traceable author statement /// 0050930 // induction of positive chemotaxis // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0042582 // azurophil granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0008201 // heparin binding // non-traceable author statement /// 0015643 // toxic substance binding // non-traceable author statement 214576_at NM_003771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003771.3 /DEF=Homo sapiens keratin, hair, acidic, 6 (KRTHA6), mRNA. /FEA=CDS /GEN=KRTHA6 /PROD=type I hair keratin 6 /DB_XREF=gi:6678648 /UG=Hs.248189 keratin, hair, acidic, 6 /FL=gb:NM_003771.3 NM_003771 keratin 36 KRT36 8689 NM_003771 /// XM_005257762 0045616 // regulation of keratinocyte differentiation // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0030280 // structural constituent of epidermis // non-traceable author statement 214577_at BG164365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG164365 /FEA=EST /DB_XREF=gi:12671068 /DB_XREF=est:602341841F1 /CLONE=IMAGE:4451986 /UG=Hs.103042 microtubule-associated protein 1B /FL=gb:NM_005909.1 BG164365 microtubule-associated protein 1B MAP1B 4131 NM_005909 /// NM_032010 /// XM_005248507 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from direct assay /// 0016358 // dendrite development // inferred from electronic annotation /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0061162 // establishment of monopolar cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214578_s_at AV683882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV683882 /FEA=EST /DB_XREF=gi:10285745 /DB_XREF=est:AV683882 /CLONE=GKCAIC05 /UG=Hs.17820 Rho-associated, coiled-coil containing protein kinase 1 /FL=gb:U43195.1 gb:NM_005406.1 AV683882 Rho-associated, coiled-coil containing protein kinase 1 ROCK1 6093 NM_005406 0003383 // apical constriction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006939 // smooth muscle contraction // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0022614 // membrane to membrane docking // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // traceable author statement /// 0032060 // bleb assembly // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045616 // regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from direct assay /// 0050901 // leukocyte tethering or rolling // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 2000114 // regulation of establishment of cell polarity // traceable author statement /// 2000145 // regulation of cell motility // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214579_at NM_020448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_020448.1 /DEF=Homo sapiens hypothetical protein dJ462O23.2 (DJ462O23.2), mRNA. /FEA=CDS /GEN=DJ462O23.2 /PROD=hypothetical protein dJ462O23.2 /DB_XREF=gi:10092686 /UG=Hs.13804 hypothetical protein dJ462O23.2 /FL=gb:NM_020448.1 NM_020448 NIPA-like domain containing 3 NIPAL3 57185 NM_020448 /// XM_005245947 /// XM_005245948 /// XM_006710780 0015693 // magnesium ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 214580_x_at AL569511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL569511 /FEA=EST /DB_XREF=gi:12924921 /DB_XREF=est:AL569511 /CLONE=CS0DE014YF20 (3 prime) /UG=Hs.321223 keratin 6B /FL=gb:NM_005555.1 AL569511 keratin 6A /// keratin 6B /// keratin 6C KRT6A /// KRT6B /// KRT6C 3853 /// 3854 /// 286887 NM_005554 /// NM_005555 /// NM_173086 0007398 // ectoderm development // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214581_x_at BE568134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE568134 /FEA=EST /DB_XREF=gi:9811854 /DB_XREF=est:601341661F1 /CLONE=IMAGE:3683823 /UG=Hs.159651 death receptor 6 /FL=gb:AF068868.1 gb:NM_014452.1 BE568134 tumor necrosis factor receptor superfamily, member 21 TNFRSF21 27242 NM_014452 0001783 // B cell apoptotic process // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031642 // negative regulation of myelination // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048713 // regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0097252 // oligodendrocyte apoptotic process // inferred from sequence or structural similarity /// 2000663 // negative regulation of interleukin-5 secretion // inferred from sequence or structural similarity /// 2000666 // negative regulation of interleukin-13 secretion // inferred from sequence or structural similarity /// 2001180 // negative regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 214582_at NM_000753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000753.1 /DEF=Homo sapiens 2,3-cyclic nucleotide 3 phosphodiesterase (CNP), mRNA. /FEA=CDS /GEN=CNP /PROD=2,3-cyclic nucleotide 3 phosphodiesterase /DB_XREF=gi:4502924 /UG=Hs.150741 2,3-cyclic nucleotide 3 phosphodiesterase /FL=gb:NM_000753.1 NM_000753 phosphodiesterase 3B, cGMP-inhibited PDE3B 5140 NM_000922 /// XM_005252972 /// XM_006718249 0001525 // angiogenesis // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from expression pattern /// 0007162 // negative regulation of cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred by curator /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred by curator /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004119 // cGMP-inhibited cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 214583_at AI268381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI268381 /FEA=EST /DB_XREF=gi:3887548 /DB_XREF=est:qm05c10.x1 /CLONE=IMAGE:1880946 /UG=Hs.239459 regulatory solute carrier protein, family 1, member 1 /FL=gb:NM_006511.1 AI268381 DNA-damage inducible 1 homolog 2 (S. cerevisiae) /// regulatory solute carrier protein, family 1, member 1 DDI2 /// RSC1A1 6248 /// 84301 NM_006511 /// NM_032341 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0051051 // negative regulation of transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008200 // ion channel inhibitor activity // traceable author statement 214584_x_at R99037 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R99037 /FEA=EST /DB_XREF=gi:985638 /DB_XREF=est:yr32a08.r1 /CLONE=IMAGE:206966 /UG=Hs.183857 acetyl-Coenzyme A carboxylase beta /FL=gb:U89344.1 gb:NM_001093.1 R99037 acetyl-CoA carboxylase beta ACACB 32 NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098 0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214585_s_at AL390171 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390171.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547I194 (from clone DKFZp547I194). /FEA=mRNA /GEN=DKFZp547I194 /PROD=hypothetical protein /DB_XREF=gi:9368867 /UG=Hs.169407 SAC2 (suppressor of actin mutations 2, yeast, homolog)-like /FL=gb:NM_022553.1 AL390171 vacuolar protein sorting 52 homolog (S. cerevisiae) VPS52 6293 NM_001289174 /// NM_001289175 /// NM_001289176 /// NM_022553 /// XM_006715163 /// XM_006715164 /// XM_006725495 /// XM_006725496 /// XM_006725709 /// XM_006725710 /// XM_006725918 /// XM_006725919 /// XM_006726011 /// XM_006726012 /// XM_006726105 /// XM_006726106 0006810 // transport // inferred from electronic annotation /// 0010668 // ectodermal cell differentiation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048611 // embryonic ectodermal digestive tract development // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214586_at T16257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T16257 /FEA=EST /DB_XREF=gi:518419 /DB_XREF=est:NIB1022 /UG=Hs.27747 G protein-coupled receptor 37 (endothelin receptor type B-like) /FL=gb:AF017262.1 gb:NM_005302.1 T16257 G protein-coupled receptor 37 (endothelin receptor type B-like) GPR37 2861 NM_005302 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 214587_at BE877796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE877796 /FEA=EST /DB_XREF=gi:10326572 /DB_XREF=est:601486365F1 /CLONE=IMAGE:3888665 /UG=Hs.114599 collagen, type VIII, alpha 1 /FL=gb:NM_001850.1 BE877796 collagen, type VIII, alpha 1 COL8A1 1295 NM_001850 /// NM_020351 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005591 // collagen type VIII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 214588_s_at R38475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R38475 /FEA=EST /DB_XREF=gi:795931 /DB_XREF=est:yf60a05.s1 /CLONE=IMAGE:26536 /UG=Hs.28785 microfibrillar-associated protein 3 /FL=gb:NM_005927.2 R38475 microfibrillar-associated protein 3 MFAP3 4238 NM_001135037 /// NM_001242336 /// NM_005927 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214589_at AL119322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL119322 /FEA=EST /DB_XREF=gi:5925221 /DB_XREF=est:DKFZp761D101_r1 /CLONE=DKFZp761D101 /UG=Hs.124752 fibroblast growth factor 12 /FL=gb:NM_021032.1 gb:U66197.1 AL119322 fibroblast growth factor 12 FGF12 2257 NM_004113 /// NM_021032 /// XM_005247227 /// XM_006713538 /// XM_006713539 0003254 // regulation of membrane depolarization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // inferred from physical interaction /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0086002 // cardiac muscle cell action potential involved in contraction // non-traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred from sequence or structural similarity /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001258 // negative regulation of cation channel activity // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity 214590_s_at AL545760 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL545760 /FEA=EST /DB_XREF=gi:12878242 /DB_XREF=est:AL545760 /CLONE=CS0DI009YK11 (5 prime) /UG=Hs.318435 ubiquitin-conjugating enzyme E2D 1 (homologous to yeast UBC45) /FL=gb:NM_003338.1 AL545760 ubiquitin-conjugating enzyme E2D 1 UBE2D1 7321 NM_001204880 /// NM_003338 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 214591_at BF215673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF215673 /FEA=EST /DB_XREF=gi:11109259 /DB_XREF=est:601881153F1 /CLONE=IMAGE:4093548 /UG=Hs.49075 Drosophila Kelch like protein /FL=gb:NM_019117.1 BF215673 kelch-like family member 4 KLHL4 56062 NM_019117 /// NM_057162 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214592_s_at BE259395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE259395 /FEA=EST /DB_XREF=gi:9129995 /DB_XREF=est:601106555F1 /CLONE=IMAGE:3342925 /UG=Hs.30174 small nuclear RNA activating complex, polypeptide 5, 19kD /FL=gb:AF093593.1 gb:NM_006049.1 BE259395 small nuclear RNA activating complex, polypeptide 5, 19kDa SNAPC5 10302 NM_006049 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 214593_at AV703470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV703470 /FEA=EST /DB_XREF=gi:10720797 /DB_XREF=est:AV703470 /CLONE=ADBBEF05 /UG=Hs.111323 Protein inhibitor of activated STAT X /FL=gb:AF077954.1 gb:NM_004671.1 AV703470 protein inhibitor of activated STAT, 2 PIAS2 9063 NM_004671 /// NM_173206 /// XM_005258377 /// XM_005258379 /// XM_005258381 /// XM_005258382 /// XM_005258383 /// XM_006722571 /// XM_006722572 /// XM_006722573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 214594_x_at BG252666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG252666 /FEA=EST /DB_XREF=gi:12762469 /DB_XREF=est:602366292F1 /CLONE=IMAGE:4474439 /UG=Hs.166196 ATPase, Class I, type 8B, member 1 /FL=gb:AF038007.1 gb:NM_005603.1 BG252666 ATPase, aminophospholipid transporter, class I, type 8B, member 1 ATP8B1 5205 NM_005603 /// XM_006722481 /// XM_006722482 0006200 // ATP catabolic process // inferred from reviewed computational analysis /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred from direct assay /// 0006869 // lipid transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // non-traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0032534 // regulation of microvillus assembly // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // inferred from direct assay /// 0045332 // phospholipid translocation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from reviewed computational analysis /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214595_at AI332979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI332979 /FEA=EST /DB_XREF=gi:4069538 /DB_XREF=est:qq18e03.x1 /CLONE=IMAGE:1932892 /UG=Hs.118695 potassium voltage-gated channel, subfamily G, member 1 /FL=gb:AF033383.1 gb:NM_002237.1 AI332979 potassium voltage-gated channel, subfamily G, member 1 KCNG1 3755 NM_002237 /// NM_172318 /// XM_006723785 /// XM_006723786 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214596_at T15991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T15991 /FEA=EST /DB_XREF=gi:518153 /DB_XREF=est:IB2413 /UG=Hs.7138 cholinergic receptor, muscarinic 3 /FL=gb:NM_000740.1 T15991 cholinergic receptor, muscarinic 3 CHRM3 1131 NM_000740 /// XM_005273032 /// XM_005273033 /// XM_005273034 /// XM_006711732 0003056 // regulation of vascular smooth muscle contraction // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046541 // saliva secretion // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032279 // asymmetric synapse // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0016907 // G-protein coupled acetylcholine receptor activity // inferred from electronic annotation /// 0042166 // acetylcholine binding // inferred from electronic annotation 214597_at BC000256 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000256.1 /DEF=Homo sapiens, Similar to somatostatin receptor 2, clone IMAGE:3357456, mRNA, partial cds. /FEA=mRNA /PROD=Similar to somatostatin receptor 2 /DB_XREF=gi:12652990 /UG=Hs.184841 somatostatin receptor 2 /FL=gb:NM_001050.1 BC000256 somatostatin receptor 2 SSTR2 6752 NM_001050 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 214598_at AL049977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049977.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C122 (from clone DKFZp564C122). /FEA=mRNA /DB_XREF=gi:4884227 /UG=Hs.162209 claudin 8 /FL=gb:NM_012132.1 AL049977 claudin 8 CLDN8 9073 NM_012132 /// NM_199328 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 214599_at NM_005547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005547.1 /DEF=Homo sapiens involucrin (IVL), mRNA. /FEA=CDS /GEN=IVL /PROD=involucrin /DB_XREF=gi:5031812 /UG=Hs.157091 involucrin /FL=gb:NM_005547.1 NM_005547 involucrin IVL 3713 NM_005547 /// XM_006711300 0010224 // response to UV-B // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay 214600_at AW771935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW771935 /FEA=EST /DB_XREF=gi:7703996 /DB_XREF=est:hn66g05.x1 /CLONE=IMAGE:3032888 /UG=Hs.155005 TEA domain family member 1 (SV40 transcriptional enhancer factor) /FL=gb:NM_021961.1 AW771935 TEA domain family member 1 (SV40 transcriptional enhancer factor) TEAD1 7003 NM_021961 0003143 // embryonic heart tube morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030903 // notochord development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214601_at AI350339 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI350339 /FEA=EST /DB_XREF=gi:4087545 /DB_XREF=est:qo33g06.x1 /CLONE=IMAGE:1910362 /UG=Hs.144563 tryptophan hydroxylase (tryptophan 5-monooxygenase) /FL=gb:NM_004179.1 gb:L29306.1 AI350339 tryptophan hydroxylase 1 TPH1 7166 NM_004179 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042427 // serotonin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 0046849 // bone remodeling // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004510 // tryptophan 5-monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016714 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214602_at D17391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D17391.1 /DEF=Human mRNA for alpha 4(IV) collagen, C-terminal. /FEA=mRNA /PROD=alpha 4(IV) collagen /DB_XREF=gi:440365 /UG=Hs.180828 collagen, type IV, alpha 4 /FL=gb:NM_000092.1 D17391 collagen, type IV, alpha 4 COL4A4 1286 NM_000092 /// XM_005246281 /// XM_005246282 /// XM_006712246 /// XM_006712247 /// XM_006712248 /// XM_006712249 /// XM_006712250 /// XM_006712251 /// XM_006712252 /// XR_427065 /// XR_427066 /// XR_427067 /// XR_427068 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype 214603_at U82671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82671 /DEF=Homo sapiens chromosome Xq28 melanoma antigen family A2a (MAGEA2A), melanoma antigen family A12 (MAGEA12), melanoma antigen family A2b (MAGEA2B), melanoma antigen family A3 (MAGEA3), caltractin (CALT), NAD(P)H dehydrogenase-like protein (NSDHL), a... /FEA=mRNA_5 /DB_XREF=gi:7280331 /UG=Hs.36980 melanoma antigen, family A, 2 /FL=gb:NM_005361.1 U82671 melanoma antigen family A, 2 /// melanoma antigen family A, 2B MAGEA2 /// MAGEA2B 4101 /// 266740 NM_001282501 /// NM_001282502 /// NM_001282504 /// NM_001282505 /// NM_005361 /// NM_153488 /// NM_175742 /// NM_175743 /// XM_005277836 /// XM_005277838 /// XM_005277839 /// XM_006724814 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0072331 // signal transduction by p53 class mediator // inferred from direct assay /// 0090398 // cellular senescence // inferred from direct assay /// 1901984 // negative regulation of protein acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from direct assay 214604_at NM_021192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_021192.1 /DEF=Homo sapiens homeo box D11 (HOXD11), mRNA. /FEA=CDS /GEN=HOXD11 /PROD=homeo box D11 /DB_XREF=gi:10864000 /UG=Hs.285508 homeo box D11 /FL=gb:NM_021192.1 NM_021192 homeobox D11 HOXD11 3237 NM_021192 /// XR_241309 0001501 // skeletal system development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001759 // organ induction // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010720 // positive regulation of cell development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214605_x_at AL046992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046992 /FEA=EST /DB_XREF=gi:5435048 /DB_XREF=est:DKFZp586L0417_r1 /CLONE=DKFZp586L0417 /UG=Hs.184907 G protein-coupled receptor 1 /FL=gb:NM_005279.1 AL046992 G protein-coupled receptor 1 GPR1 2825 NM_001098199 /// NM_001261452 /// NM_001261453 /// NM_001261454 /// NM_001261455 /// NM_005279 /// XM_005246471 /// XM_006712437 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 214606_at BF129969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF129969 /FEA=EST /DB_XREF=gi:10969009 /DB_XREF=est:601817810F1 /CLONE=IMAGE:4041171 /UG=Hs.122540 tetraspan 2 /FL=gb:AF054839.1 gb:NM_005725.1 BF129969 tetraspanin 2 TSPAN2 10100 NM_005725 /// XM_005270340 0007420 // brain development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 214607_at AW085556 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW085556 /FEA=EST /DB_XREF=gi:6040708 /DB_XREF=est:wy67b11.x1 /CLONE=IMAGE:2553597 /UG=Hs.152663 p21 (CDKN1A)-activated kinase 3 /FL=gb:AF068864.1 gb:NM_002578.1 AW085556 p21 protein (Cdc42/Rac)-activated kinase 3 PAK3 5063 NM_001128166 /// NM_001128167 /// NM_001128168 /// NM_001128172 /// NM_001128173 /// NM_002578 /// XM_005262132 /// XM_005262133 /// XM_006724654 /// XM_006724655 /// XM_006724656 /// XR_244474 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0050808 // synapse organization // traceable author statement /// 0060997 // dendritic spine morphogenesis // traceable author statement 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation 214608_s_at AJ000098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ000098.1 /DEF=Homo sapiens mRNA for EYA1C gene. /FEA=mRNA /GEN=EYA1C /DB_XREF=gi:3928169 /UG=Hs.94210 eyes absent (Drosophila) homolog 1 /FL=gb:NM_000503.1 AJ000098 EYA transcriptional coactivator and phosphatase 1 EYA1 2138 NM_000503 /// NM_001288574 /// NM_001288575 /// NM_172058 /// NM_172059 /// NM_172060 /// XM_005251182 /// XM_005251184 /// XM_006716435 /// XM_006716436 /// XM_006716437 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0014706 // striated muscle tissue development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071600 // otic vesicle morphogenesis // inferred from electronic annotation /// 0072513 // positive regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214609_at AI469991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI469991 /FEA=EST /DB_XREF=gi:4332081 /DB_XREF=est:tj89e03.x1 /CLONE=IMAGE:2148700 /UG=Hs.276879 aristaless (Drosophila) homeobox /FL=gb:NM_005169.1 AI469991 paired-like homeobox 2a PHOX2A 401 NM_005169 0003357 // noradrenergic neuron differentiation // inferred by curator /// 0003357 // noradrenergic neuron differentiation // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0021523 // somatic motor neuron differentiation // inferred from electronic annotation /// 0021623 // oculomotor nerve formation // inferred from electronic annotation /// 0021642 // trochlear nerve formation // inferred from electronic annotation /// 0021703 // locus ceruleus development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048486 // parasympathetic nervous system development // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred by curator 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214610_at AV702430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702430 /FEA=EST /DB_XREF=gi:10718760 /DB_XREF=est:AV702430 /CLONE=ADBATH08 /UG=Hs.301118 cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1 /FL=gb:NM_000497.1 AV702430 cytochrome P450, family 11, subfamily B, polypeptide 1 CYP11B1 1584 NM_000497 /// NM_001026213 /// XM_005250807 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // inferred from direct assay /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006955 // immune response // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0016125 // sterol metabolic process // traceable author statement /// 0032342 // aldosterone biosynthetic process // inferred from direct assay /// 0032342 // aldosterone biosynthetic process // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0034651 // cortisol biosynthetic process // inferred from direct assay /// 0034651 // cortisol biosynthetic process // inferred from mutant phenotype /// 0035865 // cellular response to potassium ion // inferred from expression pattern /// 0042593 // glucose homeostasis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred by curator /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004507 // steroid 11-beta-monooxygenase activity // inferred from direct assay /// 0004507 // steroid 11-beta-monooxygenase activity // inferred from mutant phenotype /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred by curator /// 0046872 // metal ion binding // inferred from electronic annotation 214611_at U16125 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U16125.1 /DEF=Human glutamatekainate receptor subunit (EEA3) mRNA, complete cds. /FEA=CDS /GEN=EAA3 /PROD=EAA3 /DB_XREF=gi:790529 /UG=Hs.181581 glutamate receptor, ionotropic, kainate 1 /FL=gb:U16125.1 U16125 glutamate receptor, ionotropic, kainate 1 GRIK1 2897 NM_000830 /// NM_175611 /// XM_005260942 /// XM_005260943 /// XM_005260944 /// XM_006723991 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0014054 // positive regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0032230 // positive regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // traceable author statement /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay 214612_x_at U10691 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U10691 /DEF=Human MAGE-6 antigen (MAGE6) gene, complete cds /FEA=mRNA /DB_XREF=gi:533522 /UG=Hs.278460 melanoma antigen, family A, 6 /FL=gb:D32076.1 gb:NM_005363.1 gb:U10339.1 U10691 melanoma antigen family A, 6 MAGEA6 4105 NM_005363 /// NM_175868 0005515 // protein binding // inferred from physical interaction 214613_at AW024085 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024085 /FEA=EST /DB_XREF=gi:5877615 /DB_XREF=est:wu62c05.x1 /CLONE=IMAGE:2524616 /UG=Hs.66542 G protein-coupled receptor 3 /FL=gb:NM_005281.1 AW024085 G protein-coupled receptor 3 GPR3 2827 NM_005281 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0040020 // regulation of meiosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214614_at AI738662 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI738662 /FEA=EST /DB_XREF=gi:5100643 /DB_XREF=est:wi11f11.x1 /CLONE=IMAGE:2389965 /UG=Hs.37035 homeo box HB9 /FL=gb:NM_005515.1 AI738662 motor neuron and pancreas homeobox 1 MNX1 3110 NM_001165255 /// NM_005515 /// XM_006715957 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021520 // spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0060539 // diaphragm development // inferred from electronic annotation /// 0060541 // respiratory system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214615_at NM_014499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014499.1 /DEF=Homo sapiens putative purinergic receptor (P2Y10), mRNA. /FEA=CDS /GEN=P2Y10 /PROD=putative purinergic receptor /DB_XREF=gi:10092632 /UG=Hs.296433 putative purinergic receptor /FL=gb:NM_014499.1 NM_014499 purinergic receptor P2Y, G-protein coupled, 10 P2RY10 27334 NM_014499 /// NM_198333 /// XM_005262124 /// XM_005262125 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation 214616_at NM_003532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003532.1 /DEF=Homo sapiens H3 histone family, member D (H3FD), mRNA. /FEA=CDS /GEN=H3FD /PROD=H3 histone family, member D /DB_XREF=gi:4504286 /UG=Hs.143522 H3 histone family, member D /FL=gb:NM_003532.1 NM_003532 histone cluster 1, H3e HIST1H3E 8353 NM_003532 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214617_at AI445650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI445650 /FEA=EST /DB_XREF=gi:4289772 /DB_XREF=est:tj08g03.x1 /CLONE=IMAGE:2140948 /UG=Hs.2200 perforin 1 (pore forming protein) /FL=gb:M28393.1 gb:NM_005041.1 AI445650 perforin 1 (pore forming protein) PRF1 5551 NM_001083116 /// NM_005041 0002357 // defense response to tumor cell // inferred from sequence or structural similarity /// 0002418 // immune response to tumor cell // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0019835 // cytolysis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031904 // endosome lumen // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0022829 // wide pore channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214618_at AF015452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF015452.1 /DEF=Homo sapiens Usurpin-gamma mRNA, complete cds. /FEA=CDS /PROD=Usurpin-gamma /DB_XREF=gi:3133284 /UG=Hs.195175 CASP8 and FADD-like apoptosis regulator /FL=gb:AF015452.1 AF015452 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0035877 // death effector domain binding // not recorded 214619_at X72304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X72304.1 /DEF=H.sapiens mRNA for corticotrophin releasing factor receptor. /FEA=mRNA /PROD=corticotrophin releasing factor receptor /DB_XREF=gi:436118 /UG=Hs.79117 corticotropin releasing hormone receptor 1 /FL=gb:L23332.1 X72304 corticotropin releasing hormone receptor 1 CRHR1 1394 NM_001145146 /// NM_001145147 /// NM_001145148 /// NM_001256299 /// NM_004382 0001666 // response to hypoxia // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007567 // parturition // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0010578 // regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0032099 // negative regulation of appetite // inferred from electronic annotation /// 0032811 // negative regulation of epinephrine secretion // inferred from electronic annotation /// 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0035902 // response to immobilization stress // inferred from electronic annotation /// 0042596 // fear response // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0051458 // corticotropin secretion // inferred from sequence or structural similarity /// 0051867 // general adaptation syndrome, behavioral process // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0071376 // cellular response to corticotropin-releasing hormone stimulus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000852 // regulation of corticosterone secretion // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015056 // corticotrophin-releasing factor receptor activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043404 // corticotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0051424 // corticotropin-releasing hormone binding // inferred from electronic annotation 214620_x_at BF038548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF038548 /FEA=EST /DB_XREF=gi:10744829 /DB_XREF=est:601459971F1 /CLONE=IMAGE:3863609 /UG=Hs.83920 peptidylglycine alpha-amidating monooxygenase /FL=gb:AF010472.1 BF038548 peptidylglycine alpha-amidating monooxygenase PAM 5066 NM_000919 /// NM_001177306 /// NM_138766 /// NM_138821 /// NM_138822 /// NR_033440 /// XM_006714632 /// XM_006714633 /// XM_006714634 /// XM_006714635 /// XM_006714636 /// XM_006714637 /// XM_006714638 /// XM_006714639 /// XM_006714640 0001519 // peptide amidation // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006518 // peptide metabolic process // inferred from electronic annotation /// 0006518 // peptide metabolic process // non-traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from mutant phenotype /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0018032 // protein amidation // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // non-traceable author statement /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004504 // peptidylglycine monooxygenase activity // inferred from direct assay /// 0004598 // peptidylamidoglycolate lyase activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214621_at S70004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S70004.1 /DEF=glycogen synthase human, liver, mRNA, 2912 nt. /FEA=mRNA /GEN=glycogen synthase /PROD=glycogen synthase /DB_XREF=gi:546960 /UG=Hs.82614 glycogen synthase 2 (liver) /FL=gb:NM_021957.1 S70004 glycogen synthase 2 (liver) GYS2 2998 NM_021957 /// XM_005253352 /// XM_005253353 /// XM_005253354 /// XM_006719062 /// XM_006719063 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from direct assay /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0043265 // ectoplasm // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004373 // glycogen (starch) synthase activity // not recorded /// 0004373 // glycogen (starch) synthase activity // inferred from direct assay /// 0004373 // glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0061547 // glycogen synthase activity, transferring glucose-1-phosphate // traceable author statement 214622_at M17252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M17252.1 /DEF=Human cytochrome P450c21 mRNA, 3 end. /FEA=mRNA /GEN=CYP21 /DB_XREF=gi:189446 /UG=Hs.278430 cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2 /FL=gb:NM_000500.1 M17252 cytochrome P450, family 21, subfamily A, polypeptide 1 pseudogene /// cytochrome P450, family 21, subfamily A, polypeptide 2 CYP21A1P /// CYP21A2 1589 /// 1590 NM_000500 /// NM_001128590 /// NR_040090 /// XM_006715001 /// XM_006715002 /// XM_006725472 /// XM_006725473 /// XM_006725896 /// XM_006725897 /// XM_006726076 /// XM_006726077 /// XR_247414 /// XR_247415 /// XR_431018 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004509 // steroid 21-monooxygenase activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214623_at AA845710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA845710 /FEA=EST /DB_XREF=gi:2931850 /DB_XREF=est:ak81b11.s1 /CLONE=IMAGE:1414269 /UG=Hs.301075 f-box and WD-40 domain protein 3 /FL=gb:AF174606.1 gb:NM_012165.1 AA845710 F-box and WD repeat domain containing 4 pseudogene 1 FBXW4P1 26226 NR_033408 214624_at AA548647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA548647 /FEA=EST /DB_XREF=gi:2318929 /DB_XREF=est:nj17e12.s1 /CLONE=IMAGE:986638 /UG=Hs.159309 uroplakin 1A /FL=gb:NM_007000.1 AA548647 uroplakin 1A UPK1A 11045 NM_001281443 /// NM_007000 0030855 // epithelial cell differentiation // inferred from direct assay /// 0051259 // protein oligomerization // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0048029 // monosaccharide binding // inferred from sequence or structural similarity 214625_s_at AF218033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF218033.1 /DEF=Homo sapiens clone PP928 unknown mRNA. /FEA=mRNA /PROD=unknown /DB_XREF=gi:10441995 /UG=Hs.112028 MisshapenNIK-related kinase /FL=gb:AB035698.1 gb:NM_015716.1 AF218033 misshapen-like kinase 1 MINK1 50488 NM_001024937 /// NM_015716 /// NM_153827 /// NM_170663 /// XM_005256664 /// XM_005256665 /// XM_005256666 /// XM_006721530 /// XM_006721531 /// XM_006721532 /// XM_006721533 /// XM_006721534 /// XM_006721535 /// XM_006721536 /// XM_006721537 /// XM_006721538 0001952 // regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214626_s_at AK026548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026548.1 /DEF=Homo sapiens cDNA: FLJ22895 fis, clone KAT04940. /FEA=mRNA /DB_XREF=gi:10439429 /UG=Hs.76847 KIAA0088 protein /FL=gb:AF144074.1 AK026548 glucosidase, alpha; neutral AB GANAB 23193 NM_001278192 /// NM_001278193 /// NM_001278194 /// NM_014610 /// NM_198334 /// NM_198335 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0017177 // glucosidase II complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0033919 // glucan 1,3-alpha-glucosidase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214627_at X14346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14346.1 /DEF=Human mRNA for eosinophil peroxidase. /FEA=mRNA /PROD=eosinophil preperoxidase (AA -127 to 575) /DB_XREF=gi:31182 /UG=Hs.46295 eosinophil peroxidase /FL=gb:NM_000502.1 X14346 eosinophil peroxidase EPX 8288 NM_000502 /// XM_006722128 0002215 // defense response to nematode // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0032693 // negative regulation of interleukin-10 production // inferred from electronic annotation /// 0032714 // negative regulation of interleukin-5 production // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072677 // eosinophil migration // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214628_at M96739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M96739.1 /DEF=Human NSCL-1 mRNA sequence. /FEA=mRNA /DB_XREF=gi:189295 /UG=Hs.30956 nescient helix loop helix 1 /FL=gb:NM_005598.1 M96739 nescient helix loop helix 1 NHLH1 4807 NM_005598 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 214629_x_at AF320999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF320999.1 /DEF=Homo sapiens Nogo-A protein short form mRNA, complete cds, alternatively spliced. /FEA=CDS /PROD=Nogo-A protein short form /DB_XREF=gi:11878277 /UG=Hs.65450 reticulon 4 /FL=gb:AF320999.1 AF320999 reticulon 4 RTN4 57142 NM_007008 /// NM_020532 /// NM_153828 /// NM_207520 /// NM_207521 /// XM_005264434 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0021801 // cerebral cortex radial glia guided migration // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from direct assay /// 0030517 // negative regulation of axon extension // inferred from direct assay /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0051960 // regulation of nervous system development // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from sequence or structural similarity 0005622 // intracellular // inferred from mutant phenotype /// 0005635 // nuclear envelope // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214630_at X54741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X54741.1 /DEF=Human CYPXIB2 gene for aldosterone synthase. /FEA=mRNA /GEN=human CYPXIB2 /PROD=aldosterone synthase (P-450aldo) /DB_XREF=gi:35199 /UG=Hs.184927 cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 /FL=gb:NM_000498.1 X54741 cytochrome P450, family 11, subfamily B, polypeptide 2 CYP11B2 1585 NM_000498 0002017 // regulation of blood volume by renal aldosterone // inferred from mutant phenotype /// 0003091 // renal water homeostasis // inferred by curator /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // inferred from direct assay /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0032342 // aldosterone biosynthetic process // inferred from direct assay /// 0032342 // aldosterone biosynthetic process // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0034651 // cortisol biosynthetic process // inferred from mutant phenotype /// 0035865 // cellular response to potassium ion // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0055075 // potassium ion homeostasis // inferred from mutant phenotype /// 0055078 // sodium ion homeostasis // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred by curator /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004507 // steroid 11-beta-monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred by curator /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047783 // corticosterone 18-monooxygenase activity // inferred from electronic annotation 214631_at BG391005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG391005 /FEA=EST /DB_XREF=gi:13284453 /DB_XREF=est:602417691F1 /CLONE=IMAGE:4536983 /UG=Hs.143604 Kaiso /FL=gb:NM_006777.2 BG391005 zinc finger and BTB domain containing 33 ZBTB33 10009 NM_001184742 /// NM_006777 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214632_at AA295257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA295257 /FEA=EST /DB_XREF=gi:1947819 /DB_XREF=est:EST100654 /UG=Hs.17778 neuropilin 2 /FL=gb:AF022860.1 gb:AF016098.1 gb:NM_003872.1 AA295257 neuropilin 2 NRP2 8828 NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934 0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214633_at AI824954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI824954 /FEA=EST /DB_XREF=gi:5445625 /DB_XREF=est:wb04c07.x1 /CLONE=IMAGE:2304684 /UG=Hs.157429 SRY (sex determining region Y)-box 3 /FL=gb:NM_005634.1 AI824954 SRY (sex determining region Y)-box 3 SOX3 6658 NM_005634 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007423 // sensory organ development // inferred from sequence or structural similarity /// 0007530 // sex determination // inferred from mutant phenotype /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from sequence or structural similarity /// 0021983 // pituitary gland development // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048515 // spermatid differentiation // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060324 // face development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement 214634_at AL523073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523073 /FEA=EST /DB_XREF=gi:12786566 /DB_XREF=est:AL523073 /CLONE=CS0DC001YE12 (5 prime) /UG=Hs.248172 H4 histone family, member M /FL=gb:NM_003495.1 AL523073 HIST1H4I 0000723 // telomere maintenance // traceable author statement /// 0006325 // chromatin organization // non-traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000786 // nucleosome // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214635_at AI701514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI701514 /FEA=EST /DB_XREF=gi:4989414 /DB_XREF=est:we35h02.x1 /CLONE=IMAGE:2343123 /UG=Hs.296949 claudin 9 /FL=gb:NM_020982.1 AI701514 claudin 9 CLDN9 9080 NM_020982 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 214636_at AA747379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA747379 /FEA=EST /DB_XREF=gi:2787337 /DB_XREF=est:nx76h04.s1 /CLONE=IMAGE:1268215 /UG=Hs.274534 calcitonin-related polypeptide, beta /FL=gb:NM_000728.1 AA747379 calcitonin-related polypeptide beta CALCB 797 NM_000728 /// XM_005253135 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0042311 // vasodilation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0005184 // neuropeptide hormone activity // traceable author statement 214637_at BG437034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG437034 /FEA=EST /DB_XREF=gi:13343540 /DB_XREF=est:602488622F1 /CLONE=IMAGE:4620821 /UG=Hs.248156 oncostatin M /FL=gb:NM_020530.1 BG437034 oncostatin M OSM 5008 NM_020530 /// XM_005261623 0002675 // positive regulation of acute inflammatory response // inferred by curator /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042503 // tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0042506 // tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042508 // tyrosine phosphorylation of Stat1 protein // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046888 // negative regulation of hormone secretion // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005900 // oncostatin-M receptor complex // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay /// 0005147 // oncostatin-M receptor binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 214638_s_at AV681875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV681875 /FEA=EST /DB_XREF=gi:10283738 /DB_XREF=est:AV681875 /CLONE=GKBAGG10 /UG=Hs.155478 cyclin T2 /FL=gb:AF048732.1 AV681875 cyclin T2 CCNT2 905 NM_001241 /// NM_058241 /// NR_037649 /// XM_005263830 /// XM_005263831 /// XM_005263832 /// XM_006712827 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0019901 // protein kinase binding // inferred from electronic annotation 214639_s_at S79910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S79910.1 /DEF=HOXA1 {alternatively spliced} human, breast adenocarcinoma MCF7 cell line, mRNA Partial, 2146 nt. /FEA=mRNA /GEN=HOXA1 /PROD=HOXA1 /DB_XREF=gi:1195535 /UG=Hs.67397 homeo box A1 /FL=gb:U10421.1 gb:NM_005522.1 S79910 homeobox A1 HOXA1 3198 NM_005522 /// NM_153620 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from direct assay /// 0007634 // optokinetic behavior // inferred from direct assay /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from mutant phenotype /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021569 // rhombomere 3 development // inferred from electronic annotation /// 0021570 // rhombomere 4 development // inferred from electronic annotation /// 0021571 // rhombomere 5 development // inferred from electronic annotation /// 0021599 // abducens nerve formation // inferred from mutant phenotype /// 0021612 // facial nerve structural organization // inferred from electronic annotation /// 0021754 // facial nucleus development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048702 // embryonic neurocranium morphogenesis // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from mutant phenotype /// 0048844 // artery morphogenesis // inferred from mutant phenotype /// 0050795 // regulation of behavior // inferred from direct assay /// 0050890 // cognition // inferred from direct assay /// 0050905 // neuromuscular process // inferred from direct assay /// 0060840 // artery development // inferred from mutant phenotype /// 0060876 // semicircular canal formation // inferred from mutant phenotype /// 0090102 // cochlea development // inferred from mutant phenotype /// 0090103 // cochlea morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214640_at AL021331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021331 /DEF=Human DNA sequence from clone 366N23 on chromosome 6q27. Contains two genes similar to consecutive parts of the C. elegans UNC-93 (protein 1, C46F11.1) gene, a KIAA0173 and Tubulin-Tyrosine Ligase LIKE gene, a Mitotic Feedback Control Protein MADP... /FEA=mRNA_1 /DB_XREF=gi:3355532 /UG=Hs.267749 unc93 (C.elegans) homolog A /FL=gb:NM_018974.1 AL021331 unc-93 homolog A (C. elegans) UNC93A 54346 NM_001143947 /// NM_018974 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 214641_at M81379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M81379.1 /DEF=H.sapiens alpha-3 type IV collagen (COL4A3) mRNA, 3 end. /FEA=mRNA /GEN=COL4A3 /PROD=alpha-3 type IV collagen /DB_XREF=gi:177893 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) /FL=gb:NM_000091.1 M81379 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 214642_x_at AI200443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI200443 /FEA=EST /DB_XREF=gi:3753049 /DB_XREF=est:qf93b07.x1 /CLONE=IMAGE:1757557 /UG=Hs.37108 melanoma antigen, family A, 5 /FL=gb:NM_021049.1 AI200443 MAGEA10-MAGEA5 readthrough /// melanoma antigen family A, 5 MAGEA10-MAGEA5 /// MAGEA5 4104 /// 100533997 NM_001204811 /// NM_021049 0005634 // nucleus // inferred from electronic annotation 214643_x_at BG034080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG034080 /FEA=EST /DB_XREF=gi:12427028 /DB_XREF=est:602302516F1 /CLONE=IMAGE:4404314 /UG=Hs.193163 bridging integrator 1 /FL=gb:AF043898.1 BG034080 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 214644_at BF061074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF061074 /FEA=EST /DB_XREF=gi:10819984 /DB_XREF=est:7i80c08.x1 /CLONE=IMAGE:3341006 /UG=Hs.131954 H2A histone family, member D /FL=gb:NM_003510.1 BF061074 histone cluster 1, H2ak HIST1H2AK 8330 NM_003510 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214645_at AK025116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025116.1 /DEF=Homo sapiens cDNA: FLJ21463 fis, clone COL04765. /FEA=mRNA /DB_XREF=gi:10437568 /UG=Hs.287667 hypothetical protein FLJ21463 /FL=gb:NM_025035.1 AK025116 214646_at AL522145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL522145 /FEA=EST /DB_XREF=gi:12785638 /DB_XREF=est:AL522145 /CLONE=CS0DB007YJ08 (5 prime) /UG=Hs.247696 H3 histone family, member J /FL=gb:NM_003535.1 AL522145 histone cluster 1, H3a /// histone cluster 1, H3b /// histone cluster 1, H3c /// histone cluster 1, H3d /// histone cluster 1, H3e /// histone cluster 1, H3f /// histone cluster 1, H3g /// histone cluster 1, H3h /// histone cluster 1, H3i /// histone cluster 1, H3j HIST1H3A /// HIST1H3B /// HIST1H3C /// HIST1H3D /// HIST1H3E /// HIST1H3F /// HIST1H3G /// HIST1H3H /// HIST1H3I /// HIST1H3J 8350 /// 8351 /// 8352 /// 8353 /// 8354 /// 8355 /// 8356 /// 8357 /// 8358 /// 8968 NM_003529 /// NM_003530 /// NM_003531 /// NM_003532 /// NM_003533 /// NM_003534 /// NM_003535 /// NM_003536 /// NM_003537 /// NM_021018 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0051320 // S phase // non-traceable author statement /// 0060968 // regulation of gene silencing // inferred from direct assay 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214647_s_at BG402460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG402460 /FEA=EST /DB_XREF=gi:13295908 /DB_XREF=est:602466163F1 /CLONE=IMAGE:4594359 /UG=Hs.20019 hemochromatosis /FL=gb:AF079407.1 BG402460 hemochromatosis HFE 3077 NM_000410 /// NM_139002 /// NM_139003 /// NM_139004 /// NM_139005 /// NM_139006 /// NM_139007 /// NM_139008 /// NM_139009 /// NM_139010 /// NM_139011 /// XM_006715075 /// XR_241893 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010106 // cellular response to iron ion starvation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060586 // multicellular organismal iron ion homeostasis // inferred from electronic annotation /// 0097459 // iron ion import into cell // inferred from direct assay 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0003823 // antigen binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from electronic annotation 214648_at AI207120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI207120 /FEA=EST /DB_XREF=gi:3765792 /DB_XREF=est:qf59e09.x1 /CLONE=IMAGE:1754344 /UG=Hs.248129 glutathione peroxidase 5 (epididymal androgen-related protein) /FL=gb:NM_001509.1 AI207120 glutathione peroxidase 5 (epididymal androgen-related protein) GPX5 2880 NM_001509 /// NM_003996 0006629 // lipid metabolic process // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 214649_s_at U58033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U58033.1 /DEF=Homo sapiens myotubularin related protein 2 (MTMR2) mRNA, partial cds. /FEA=mRNA /GEN=MTMR2 /PROD=myotubularin related protein 2 /DB_XREF=gi:3912941 /UG=Hs.278491 myotubularin related protein 2 /FL=gb:NM_003912.1 U58033 myotubularin related protein 2 MTMR2 8898 NM_001243571 /// NM_016156 /// NM_201278 /// NM_201281 /// XM_005274374 /// XM_005274375 /// XM_006718933 /// XM_006718934 /// XM_006718935 /// XM_006718936 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from sequence or structural similarity /// 2000645 // negative regulation of receptor catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052866 // phosphatidylinositol phosphate phosphatase activity // inferred from electronic annotation 214650_x_at AL050328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050328 /DEF=Human DNA sequence from clone RP11-145L22 on chromosome 6p21.32-22.2. Contains the gene for myelinoligodendrocyte glycoprotein MOG, (part of) the gene for a novel KRAB box containing C2H2 type zinc finger protein, ESTs, STSs, GSSs and a putative ... /FEA=mRNA_4 /DB_XREF=gi:7530094 /UG=Hs.141308 myelin oligodendrocyte glycoprotein /FL=gb:U18799.1 gb:U18803.1 AL050328 myelin oligodendrocyte glycoprotein MOG 4340 NM_001008228 /// NM_001008229 /// NM_001170418 /// NM_002433 /// NM_206809 /// NM_206810 /// NM_206811 /// NM_206812 /// NM_206813 /// NM_206814 /// XM_005249131 /// XM_005249139 /// XM_005249140 /// XM_005272820 /// XM_005272829 /// XM_005272830 /// XM_005274865 /// XM_005274874 /// XM_005274875 /// XM_005274977 /// XM_005274986 /// XM_005275125 /// XM_005275134 /// XM_005275252 /// XM_005275261 /// XM_005275262 /// XM_005275410 /// XM_005275419 /// XM_005275558 /// XM_005275567 /// XM_005275568 0007155 // cell adhesion // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0034126 // positive regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214651_s_at U41813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U41813.1 /DEF=Human class I homeoprotein (HOXA9) mRNA, partial cds. /FEA=mRNA /GEN=HOXA9 /PROD=HOXA9 /DB_XREF=gi:1184168 /UG=Hs.127428 homeo box A9 /FL=gb:NM_002142.1 U41813 HOXA10-HOXA9 readthrough /// homeobox A9 /// microRNA 196b HOXA10-HOXA9 /// HOXA9 /// MIR196B 3205 /// 442920 /// 100534589 NM_152739 /// NR_029911 /// NR_037940 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from mutant phenotype /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214652_at X58987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X58987.1 /DEF=Human mRNA for D-1 dopamine receptor. /FEA=mRNA /PROD=D-1 dopamine receptor /DB_XREF=gi:30398 /UG=Hs.2624 dopamine receptor D1 /FL=gb:NM_000794.1 X58987 dopamine receptor D1 DRD1 1812 NM_000794 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from direct assay /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007610 // behavior // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007617 // mating behavior // inferred from sequence or structural similarity /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0015872 // dopamine transport // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0035106 // operant conditioning // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0046323 // glucose import // inferred from electronic annotation /// 0046959 // habituation // inferred from electronic annotation /// 0046960 // sensitization // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from direct assay /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from genetic interaction /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001588 // dopamine neurotransmitter receptor activity, coupled via Gs // inferred from direct assay /// 0001588 // dopamine neurotransmitter receptor activity, coupled via Gs // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035240 // dopamine binding // inferred from mutant phenotype 214655_at U18549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U18549 /DEF=Human GPR6 G protein-coupled receptor gene, complete cds /FEA=mRNA /DB_XREF=gi:604501 /UG=Hs.46332 G protein-coupled receptor 6 /FL=gb:NM_005284.1 U18549 G protein-coupled receptor 6 GPR6 2830 NM_001286099 /// NM_005284 0003376 // sphingosine-1-phosphate signaling pathway // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0038036 // sphingosine-1-phosphate receptor activity // inferred from electronic annotation 214656_x_at BE790157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE790157 /FEA=EST /DB_XREF=gi:10211355 /DB_XREF=est:601482981F1 /CLONE=IMAGE:3885236 /UG=Hs.286226 myosin IB BE790157 myosin IC MYO1C 4641 NM_001080779 /// NM_001080950 /// NM_033375 /// XM_005256655 0006605 // protein targeting // inferred from direct assay /// 0006612 // protein targeting to membrane // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0038089 // positive regulation of cell migration by vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from mutant phenotype /// 1900748 // positive regulation of vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005903 // brush border // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045160 // myosin I complex // inferred from electronic annotation /// 0060171 // stereocilium membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 214657_s_at AU134977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU134977 /FEA=EST /DB_XREF=gi:10995516 /DB_XREF=est:AU134977 /CLONE=PLACE1000926 /UG=Hs.322149 Human clone 137308 mRNA, partial cds AU134977 microRNA 612 /// nuclear paraspeckle assembly transcript 1 (non-protein coding) MIR612 /// NEAT1 283131 /// 693197 NR_002802 /// NR_028272 /// NR_030343 214658_at BG286537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG286537 /FEA=EST /DB_XREF=gi:13039504 /DB_XREF=est:602382536F1 /CLONE=IMAGE:4500129 /UG=Hs.278391 CGI-109 protein BG286537 transmembrane emp24 protein transport domain containing 7 /// TMED7-TICAM2 readthrough TMED7 /// TMED7-TICAM2 51014 /// 100302736 NM_001164468 /// NM_001164469 /// NM_181836 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035669 // TRAM-dependent toll-like receptor 4 signaling pathway // inferred from direct assay /// 0035669 // TRAM-dependent toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0071650 // negative regulation of chemokine (C-C motif) ligand 5 production // inferred from mutant phenotype /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // inferred from mutant phenotype /// 2000494 // positive regulation of interleukin-18-mediated signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // traceable author statement /// 0030127 // COPII vesicle coat // traceable author statement /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype 214659_x_at AC007956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007956 /DEF=Homo sapiens chromosome 14 clones CTD-3211F8 and RP11-173A8 containing KIAA0317 gene, complete cds; and unknown gene /FEA=CDS_1 /DB_XREF=gi:7341426 /UG=Hs.159471 ZAP3 protein AC007956 YLP motif containing 1 YLPM1 56252 NM_019589 /// XM_005267860 /// XR_245704 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032204 // regulation of telomere maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214660_at X68742 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68742.1 /DEF=H.sapiens mRNA for integrin, alpha subunit. /FEA=mRNA /DB_XREF=gi:33949 /UG=Hs.116774 integrin, alpha 1 X68742 integrin, alpha 1 ITGA1 3672 NM_181501 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042311 // vasodilation // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045123 // cellular extravasation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070481 // nuclear-transcribed mRNA catabolic process, non-stop decay // inferred from electronic annotation /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from electronic annotation /// 0071025 // RNA surveillance // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214661_s_at R06783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R06783 /FEA=EST /DB_XREF=gi:757403 /DB_XREF=est:yf11h07.s1 /CLONE=IMAGE:126589 /UG=Hs.117487 gene near HD on 4p16.3 with homology to hypothetical S. pombe gene R06783 NOP14 nucleolar protein NOP14 8602 NM_001291978 /// NM_001291979 /// NM_003703 /// XM_006713929 /// XR_241655 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0000472 // endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0000480 // endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from sequence or structural similarity /// 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042274 // ribosomal small subunit biogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030686 // 90S preribosome // inferred from sequence or structural similarity /// 0030692 // Noc4p-Nop14p complex // inferred from sequence or structural similarity /// 0032040 // small-subunit processome // inferred from sequence or structural similarity 0019899 // enzyme binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 214662_at D26488 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D26488.1 /DEF=Human mRNA for KIAA0007 gene, partial cds. /FEA=mRNA /GEN=KIAA0007 /DB_XREF=gi:452522 /UG=Hs.90315 KIAA0007 protein D26488 WD repeat domain 43 WDR43 23160 NM_015131 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214663_at AB007941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007941.1 /DEF=Homo sapiens mRNA for KIAA0472 protein, partial cds. /FEA=mRNA /GEN=KIAA0472 /PROD=KIAA0472 protein /DB_XREF=gi:3413905 /UG=Hs.6874 KIAA0472 protein AB007941 dual serine/threonine and tyrosine protein kinase DSTYK 25778 NM_015375 /// NM_199462 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214664_at AU121975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU121975 /FEA=EST /DB_XREF=gi:10937210 /DB_XREF=est:AU121975 /CLONE=MAMMA1001393 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase AU121975 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 /// XM_006714035 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // traceable author statement /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034023 // 5-(carboxyamino)imidazole ribonucleotide mutase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 214665_s_at AK000095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000095.1 /DEF=Homo sapiens cDNA FLJ20088 fis, clone COL03869. /FEA=mRNA /DB_XREF=gi:7019960 /UG=Hs.85301 calcium binding protein P22 AK000095 calcineurin-like EF-hand protein 1 CHP1 11261 NM_007236 /// XM_005254140 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0022406 // membrane docking // inferred from sequence or structural similarity /// 0031122 // cytoplasmic microtubule organization // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0031953 // negative regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from sequence or structural similarity /// 0042308 // negative regulation of protein import into nucleus // inferred from direct assay /// 0045056 // transcytosis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051222 // positive regulation of protein transport // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060050 // positive regulation of protein glycosylation // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from sequence or structural similarity /// 0061025 // membrane fusion // inferred from sequence or structural similarity /// 0070885 // negative regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0071468 // cellular response to acidity // inferred from sequence or structural similarity /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay 214666_x_at AI204981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI204981 /FEA=EST /DB_XREF=gi:3758043 /DB_XREF=est:an03a07.x1 /CLONE=IMAGE:1684500 /UG=Hs.295789 iron-responsive element binding protein 2 AI204981 iron-responsive element binding protein 2 IREB2 3658 NM_004136 0006417 // regulation of translation // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006826 // iron ion transport // traceable author statement /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010040 // response to iron(II) ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030350 // iron-responsive element binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 214667_s_at AK026607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026607.1 /DEF=Homo sapiens cDNA: FLJ22954 fis, clone KAT09813, highly similar to AF010315 Homo sapiens Pig11 (PIG11) mRNA. /FEA=mRNA /DB_XREF=gi:10439496 /UG=Hs.96908 p53-induced protein AK026607 tumor protein p53 inducible protein 11 TP53I11 9537 NM_001076787 /// NM_001258320 /// NM_001258321 /// NM_001258322 /// NM_001258323 /// NM_001258324 /// NM_006034 /// XM_005253227 /// XM_005253229 /// XM_006718387 /// XR_242833 /// XR_428864 0006950 // response to stress // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214668_at BG532405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG532405 /FEA=EST /DB_XREF=gi:13523943 /DB_XREF=est:602561918F1 /CLONE=IMAGE:4699709 /UG=Hs.44235 hypothetical protein from clone 24774 BG532405 SPRY domain containing 7 SPRYD7 57213 NM_001127482 /// NM_020456 /// NR_023351 0005515 // protein binding // inferred from electronic annotation 214669_x_at BG485135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG485135 /FEA=EST /DB_XREF=gi:13417414 /DB_XREF=est:602503756F1 /CLONE=IMAGE:4617445 /UG=Hs.325722 immunoglobulin kappa variable 3D-15 BG485135 immunoglobulin kappa constant IGKC 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 214670_at AA653300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA653300 /FEA=EST /DB_XREF=gi:2589471 /DB_XREF=est:ag65c10.s1 /CLONE=IMAGE:1127826 /UG=Hs.132390 zinc finger protein 36 (KOX 18) AA653300 zinc finger with KRAB and SCAN domains 1 ZKSCAN1 7586 NM_001287054 /// NM_001287055 /// NM_003439 /// XM_005250565 /// XM_006716112 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214671_s_at L19704 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L19704 /DEF=Human ABR gene, complete cds and flanking regions /FEA=CDS /DB_XREF=gi:388302 /UG=Hs.118021 active BCR-related gene L19704 active BCR-related ABR 29 NM_001092 /// NM_001159746 /// NM_001256847 /// NM_001282149 /// NM_021962 /// XM_006721506 /// XM_006721507 /// XM_006721508 /// XM_006721509 /// XM_006721510 /// XM_006721511 /// XM_006721512 /// XM_006725292 /// XM_006725293 /// XM_006725294 /// XM_006725295 /// XM_006725296 /// XM_006725297 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043314 // negative regulation of neutrophil degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 214672_at AB023215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023215.1 /DEF=Homo sapiens mRNA for KIAA0998 protein, partial cds. /FEA=mRNA /GEN=KIAA0998 /PROD=KIAA0998 protein /DB_XREF=gi:4589639 /UG=Hs.131525 KIAA0998 protein AB023215 tubulin tyrosine ligase-like family, member 5 TTLL5 23093 NM_015072 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 214673_s_at AU140931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU140931 /FEA=EST /DB_XREF=gi:11002452 /DB_XREF=est:AU140931 /CLONE=PLACE4000517 /UG=Hs.155101 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle AU140931 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase HUWE1 10075 NM_031407 /// XM_005261965 /// XM_005261966 /// XM_005261967 /// XM_005261968 /// XM_005261969 /// XM_005261971 /// XM_005261972 /// XM_006724574 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214674_at AW451502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451502 /FEA=EST /DB_XREF=gi:6992278 /DB_XREF=est:UI-H-BI3-ali-h-07-0-UI.s1 /CLONE=IMAGE:2737020 /UG=Hs.301373 ubiquitin specific protease 19 AW451502 ubiquitin specific peptidase 19 USP19 10869 NM_001199160 /// NM_001199161 /// NM_001199162 /// NM_006677 /// XM_005264823 /// XM_005264824 /// XM_005264825 /// XM_005264826 /// XM_005264827 /// XM_005264828 /// XM_005264829 /// XM_005264830 /// XM_005264831 /// XM_006712946 /// XM_006712947 /// XM_006712948 /// XM_006712949 /// XM_006712950 /// XM_006712951 /// XM_006712952 /// XM_006712953 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from sequence or structural similarity /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from expression pattern /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from sequence or structural similarity /// 0090068 // positive regulation of cell cycle process // inferred from sequence or structural similarity /// 1900037 // regulation of cellular response to hypoxia // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214675_at BC005407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005407.1 /DEF=Homo sapiens, clone IMAGE:3461492, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3461492) /DB_XREF=gi:13529307 /UG=Hs.30002 SH3-containing protein SH3GLB2 BC005407 nucleoporin 188kDa NUP188 23511 NM_015354 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 214676_x_at AF113616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113616 /DEF=Homo sapiens intestinal mucin 3 (MUC3) gene, partial cds /FEA=mRNA /DB_XREF=gi:6466800 /UG=Hs.129782 mucin 3A, intestinal AF113616 mucin 3B, cell surface associated MUC3B 57876 XM_005276299 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 214677_x_at X57812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X57812.1 /DEF=Human rearranged immunoglobulin lambda light chain mRNA. /FEA=mRNA /GEN=immunoglobulin lambda light chain /DB_XREF=gi:33723 /UG=Hs.289110 immunoglobulin lambda joining 3 X57812 immunoglobulin lambda constant 1 (Mcg marker) IGLC1 3537 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 214678_x_at R51161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R51161 /FEA=EST /DB_XREF=gi:813063 /DB_XREF=est:yg71f08.r1 /CLONE=IMAGE:38659 /UG=Hs.2074 zinc finger protein, X-linked R51161 zinc finger protein, X-linked ZFX 7543 NM_001178084 /// NM_001178085 /// NM_001178086 /// NM_001178095 /// NM_003410 /// XM_005274591 /// XM_005274592 /// XM_005274594 /// XM_006724513 /// XM_006724514 /// XM_006724515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060746 // parental behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214679_x_at AL110227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110227.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194). /FEA=mRNA /DB_XREF=gi:5817165 /UG=Hs.323067 Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194) AL110227 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 214680_at BF674712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF674712 /FEA=EST /DB_XREF=gi:11948607 /DB_XREF=est:602136853F1 /CLONE=IMAGE:4273260 /UG=Hs.47860 neurotrophic tyrosine kinase, receptor, type 2 BF674712 neurotrophic tyrosine kinase, receptor, type 2 NTRK2 4915 NM_001007097 /// NM_001018064 /// NM_001018065 /// NM_001018066 /// NM_001291937 /// NM_006180 /// XM_005252001 /// XM_005252003 /// XM_005252004 /// XM_005252006 /// XM_005252007 /// XM_006717120 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from electronic annotation /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043121 // neurotrophin binding // inferred from direct assay /// 0043121 // neurotrophin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0048403 // brain-derived neurotrophic factor binding // inferred from sequence or structural similarity /// 0060175 // brain-derived neurotrophic factor-activated receptor activity // inferred from mutant phenotype 214681_at AI830490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI830490 /FEA=EST /DB_XREF=gi:5451161 /DB_XREF=est:wh51g07.x1 /CLONE=IMAGE:2384316 /UG=Hs.1466 glycerol kinase AI830490 glycerol kinase GK 2710 NM_000167 /// NM_001128127 /// NM_001205019 /// NM_203391 /// XM_005274488 /// XM_006724483 /// XM_006724484 /// XM_006724485 /// XM_006724486 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from mutant phenotype /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046167 // glycerol-3-phosphate biosynthetic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // inferred from mutant phenotype /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 214682_at AK023376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023376.1 /DEF=Homo sapiens cDNA FLJ13314 fis, clone OVARC1001506, highly similar to POLYCYSTIN PRECURSOR. /FEA=mRNA /DB_XREF=gi:10435286 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) AK023376 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 PKD1P1 339044 NR_036447 0016021 // integral component of membrane // inferred from electronic annotation 214683_s_at AI251890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI251890 /FEA=EST /DB_XREF=gi:3848419 /DB_XREF=est:qu78d12.x1 /CLONE=IMAGE:1978199 /UG=Hs.2083 CDC-like kinase1 AI251890 CDC-like kinase 1 CLK1 1195 NM_001024646 /// NM_001162407 /// NM_004071 /// NR_027855 /// NR_027856 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214684_at X63381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63381.1 /DEF=Homo sapiens mRNA for serum response factor-related protein, RSRFC4. /FEA=mRNA /GEN=RSRFC4 /PROD=serum response factor-related protein /DB_XREF=gi:432655 /UG=Hs.182280 MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) X63381 myocyte enhancer factor 2A MEF2A 4205 NM_001130926 /// NM_001130927 /// NM_001130928 /// NM_001171894 /// NM_005587 /// XM_005254914 /// XM_005254915 /// XM_005254916 /// XM_006720509 /// XM_006720510 /// XM_006720511 /// XM_006720512 /// XM_006720513 /// XM_006720514 /// XM_006720515 /// XM_006720516 /// XM_006720517 /// XM_006720518 /// XM_006720519 /// XM_006720520 /// XM_006720521 0000002 // mitochondrial genome maintenance // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from direct assay /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003138 // primary heart field specification // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003185 // sinoatrial valve morphogenesis // inferred from electronic annotation /// 0003211 // cardiac ventricle formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from expression pattern /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035984 // cellular response to trichostatin A // inferred from electronic annotation /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045652 // regulation of megakaryocyte differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048311 // mitochondrion distribution // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0055005 // ventricular cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060025 // regulation of synaptic activity // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0061333 // renal tubule morphogenesis // inferred from electronic annotation /// 0061337 // cardiac conduction // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071498 // cellular response to fluid shear stress // inferred from electronic annotation /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from electronic annotation /// 0072102 // glomerulus morphogenesis // inferred from electronic annotation /// 0072160 // nephron tubule epithelial cell differentiation // inferred from electronic annotation /// 0090073 // positive regulation of protein homodimerization activity // inferred from electronic annotation /// 2000111 // positive regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 214685_at AB000464 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB000464.1 /DEF=Homo sapiens mRNA, exon 1, 2, 3, 4, clone:RES4-24A. /FEA=mRNA /DB_XREF=gi:1843395 /UG=Hs.104258 Homo sapiens mRNA, exon 1, 2, 3, 4, clone:RES4-24A AB000464 NOP14 antisense RNA 1 NOP14-AS1 317648 NR_015453 214686_at AA868898 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA868898 /FEA=EST /DB_XREF=gi:2964343 /DB_XREF=est:ak55b08.s1 /CLONE=IMAGE:1409847 /UG=Hs.118281 zinc finger protein 266 AA868898 zinc finger protein 266 ZNF266 10781 NM_001271314 /// NM_006631 /// NM_198058 /// XM_005259713 /// XM_005259714 /// XM_005259716 /// XM_006722620 /// XM_006722621 /// XM_006722622 /// XM_006722623 /// XM_006722624 /// XM_006722625 /// XM_006722626 /// XM_006722627 /// XM_006722628 /// XM_006722629 /// XM_006722630 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214687_x_at AK026577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026577.1 /DEF=Homo sapiens cDNA: FLJ22924 fis, clone KAT06977, highly similar to HSALDAR Human fibroblast mRNA for aldolase A. /FEA=mRNA /DB_XREF=gi:10439461 /UG=Hs.273415 aldolase A, fructose-bisphosphate AK026577 aldolase A, fructose-bisphosphate ALDOA 226 NM_000034 /// NM_001127617 /// NM_001243175 /// NM_001243177 /// NM_184041 /// NM_184043 /// XM_006721109 0002576 // platelet degranulation // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from mutant phenotype /// 0006096 // glycolytic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0007015 // actin filament organization // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031430 // M band // inferred from electronic annotation /// 0031674 // I band // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015631 // tubulin binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070061 // fructose binding // inferred from direct assay 214688_at BF217301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF217301 /FEA=EST /DB_XREF=gi:11110887 /DB_XREF=est:601885646F1 /CLONE=IMAGE:4104322 /UG=Hs.83958 transducin-like enhancer of split 4, homolog of Drosophila E(sp1) BF217301 transducin-like enhancer of split 4 TLE4 7091 NM_001282748 /// NM_001282749 /// NM_001282753 /// NM_001282760 /// NM_007005 /// NR_104239 /// XM_005252167 /// XM_005252169 /// XM_005252173 /// XM_005252174 /// XM_005252175 /// XM_005252177 /// XM_006717264 /// XM_006717265 /// XM_006717266 /// XM_006717267 /// XM_006717268 /// XM_006717269 /// XM_006717270 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 214689_at BF435151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF435151 /FEA=EST /DB_XREF=gi:11447439 /DB_XREF=est:nab43e05.x1 /CLONE=IMAGE:3268689 /UG=Hs.293896 pregnancy-associated plasma protein-E BF435151 pappalysin 2 PAPPA2 60676 NM_020318 /// NM_021936 /// XM_005245422 0001558 // regulation of cell growth // non-traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214690_at AA004579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA004579 /FEA=EST /DB_XREF=gi:1448706 /DB_XREF=est:zh95a02.r1 /CLONE=IMAGE:429002 /UG=Hs.121044 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD AA004579 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa TAF1B 9014 NM_005680 0001189 // RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript // inferred from direct assay /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070860 // RNA polymerase I core factor complex // inferred from direct assay 0001164 // RNA polymerase I CORE element sequence-specific DNA binding // inferred from direct assay /// 0001187 // RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214691_x_at AU121431 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU121431 /FEA=EST /DB_XREF=gi:10936666 /DB_XREF=est:AU121431 /CLONE=MAMMA1000110 /UG=Hs.40719 hypothetical protein KIAA1164 AU121431 family with sequence similarity 63, member B FAM63B 54629 NM_001040450 /// NM_001040453 /// NM_019092 214692_s_at AL041139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL041139 /FEA=EST /DB_XREF=gi:5935356 /DB_XREF=est:DKFZp434E2316_r1 /CLONE=DKFZp434E2316 /UG=Hs.142296 jerky (mouse) homolog AL041139 Jrk homolog (mouse) JRK 8629 NM_001077527 /// NM_001279352 /// NM_003724 /// XM_006716677 /// XM_006716678 /// XM_006716679 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214693_x_at BE732345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE732345 /FEA=EST /DB_XREF=gi:10146337 /DB_XREF=est:601566954F1 /CLONE=IMAGE:3841692 /UG=Hs.41569 phosphatidic acid phosphatase type 2A BE732345 neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 26 /// neuroblastoma breakpoint family, member 9 NBPF10 /// NBPF14 /// NBPF26 /// NBPF9 25832 /// 400818 /// 100132406 /// 101060684 NM_001037675 /// NM_001039703 /// NM_001277444 /// NM_015383 /// XM_003960230 /// XM_005276139 /// XM_005276140 /// XM_005277503 /// XM_005277504 /// XM_005277505 /// XM_006711091 /// XM_006711092 /// XM_006711093 /// XM_006711094 /// XM_006711095 /// XM_006711096 /// XM_006711265 /// XM_006711317 /// XM_006726340 /// XM_006726341 /// XM_006726342 /// XM_006726343 /// XM_006726344 /// XM_006726345 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 214694_at N31673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N31673 /FEA=EST /DB_XREF=gi:1152072 /DB_XREF=est:yx69d02.r1 /CLONE=IMAGE:266979 /UG=Hs.84883 KIAA0864 protein N31673 myosin phosphatase Rho interacting protein MPRIP 23164 NM_015134 /// NM_201274 /// XM_005256563 /// XM_005256564 /// XM_006721487 /// XM_006721488 /// XM_006721489 /// XM_006721490 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214695_at AW051361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW051361 /FEA=EST /DB_XREF=gi:5913631 /DB_XREF=est:wy89h03.x1 /CLONE=IMAGE:2555765 /UG=Hs.8127 KIAA0144 gene product AW051361 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214696_at AF070569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070569.1 /DEF=Homo sapiens clone 24659 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387938 /UG=Hs.29206 Homo sapiens clone 24659 mRNA sequence AF070569 microRNA 22 /// MIR22 host gene (non-protein coding) MIR22 /// MIR22HG 84981 /// 407004 NM_001001870 /// NM_032895 /// NR_028502 /// NR_028503 /// NR_028504 /// NR_028505 /// NR_029494 214697_s_at AW190873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190873 /FEA=EST /DB_XREF=gi:6465353 /DB_XREF=est:xl66a01.x1 /CLONE=IMAGE:2679624 /UG=Hs.145078 regulator of differentiation (in S. pombe) 1 AW190873 polypyrimidine tract binding protein 3 PTBP3 9991 NM_001163788 /// NM_001163790 /// NM_001244896 /// NM_001244897 /// NM_001244898 /// NM_005156 /// XM_005252324 /// XM_006717343 /// XM_006717344 /// XM_006717345 /// XM_006717346 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 214698_at AW190873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190873 /FEA=EST /DB_XREF=gi:6465353 /DB_XREF=est:xl66a01.x1 /CLONE=IMAGE:2679624 /UG=Hs.145078 regulator of differentiation (in S. pombe) 1 AW190873 polypyrimidine tract binding protein 3 PTBP3 9991 NM_001163788 /// NM_001163790 /// NM_001244896 /// NM_001244897 /// NM_001244898 /// NM_005156 /// XM_005252324 /// XM_006717343 /// XM_006717344 /// XM_006717345 /// XM_006717346 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 214699_x_at AK024279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024279.1 /DEF=Homo sapiens cDNA FLJ14217 fis, clone NT2RP3003680, highly similar to Homo sapiens mRNA; cDNA DKFZp434J154 (from clone DKFZp434J154). /FEA=mRNA /DB_XREF=gi:10436620 /UG=Hs.226372 DKFZP434J154 protein AK024279 WD repeat domain, phosphoinositide interacting 2 WIPI2 26100 NM_001033518 /// NM_001033519 /// NM_001033520 /// NM_001278299 /// NM_015610 /// NM_016003 /// XM_006715685 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000421 // autophagic vacuole membrane // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 214700_x_at AK000323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000323.1 /DEF=Homo sapiens cDNA FLJ20316 fis, clone HEP07903, highly similar to U79263 Human clone 23760 mRNA. /FEA=mRNA /DB_XREF=gi:7020332 /UG=Hs.225841 DKFZP434D193 protein AK000323 uncharacterized LOC101929336 /// replication timing regulatory factor 1 LOC101929336 /// RIF1 55183 /// 101929336 NM_001177663 /// NM_001177664 /// NM_001177665 /// NM_018151 /// XM_005246665 /// XM_006712609 /// XM_006712610 /// XM_006712611 /// XR_241332 /// XR_251199 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000723 // telomere maintenance // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 214701_s_at AJ276395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276395.1 /DEF=Homo sapiens mRNA for MSF-FN70 (FN gene). /FEA=mRNA /GEN=FN /PROD=migration stimulation factor FN70 /DB_XREF=gi:12053816 /UG=Hs.321592 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 214702_at AJ276395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276395.1 /DEF=Homo sapiens mRNA for MSF-FN70 (FN gene). /FEA=mRNA /GEN=FN /PROD=migration stimulation factor FN70 /DB_XREF=gi:12053816 /UG=Hs.321592 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 214703_s_at AW954107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW954107 /FEA=EST /DB_XREF=gi:8143790 /DB_XREF=est:EST366177 /UG=Hs.303394 Homo sapiens cDNA: FLJ22150 fis, clone HRC00109 AW954107 mannosidase, alpha, class 2B, member 2 MAN2B2 23324 NM_001292038 /// NM_015274 /// XR_241647 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214704_at AK024679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024679.1 /DEF=Homo sapiens cDNA: FLJ21026 fis, clone CAE06812. /FEA=mRNA /DB_XREF=gi:10437019 /UG=Hs.317585 Homo sapiens cDNA: FLJ21026 fis, clone CAE06812 AK024679 transcription factor 25 (basic helix-loop-helix) TCF25 22980 NM_014972 /// XM_005256297 /// XM_005256298 /// XM_005256299 /// XM_005256300 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // non-traceable author statement 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214705_at AJ001306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001306.1 /DEF=Homo sapiens mRNA for PDZ domain protein. /FEA=mRNA /PROD=PDZ domain protein /DB_XREF=gi:2370148 /UG=Hs.321197 PDZ domain protein (Drosophila inaD-like) AJ001306 InaD-like (Drosophila) INADL 10207 NM_005799 /// NM_176877 /// NM_176878 /// XM_005270341 /// XM_005270343 /// XM_005270345 /// XM_005270347 /// XM_006710275 /// XM_006710276 /// XM_006710277 /// XM_006710278 0034329 // cell junction assembly // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214706_at AU149447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU149447 /FEA=EST /DB_XREF=gi:11010968 /DB_XREF=est:AU149447 /CLONE=NT2RM4002334 /UG=Hs.88219 zinc finger protein 200 AU149447 zinc finger protein 200 ZNF200 7752 NM_001145446 /// NM_001145447 /// NM_001145448 /// NM_003454 /// NM_198087 /// NM_198088 /// XM_005255556 /// XM_006720940 /// XM_006720941 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214707_x_at AB002326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002326.2 /DEF=Homo sapiens mRNA for KIAA0328 protein, partial cds. /FEA=mRNA /GEN=KIAA0328 /PROD=KIAA0328 protein /DB_XREF=gi:6634016 /UG=Hs.97393 KIAA0328 protein AB002326 Alstrom syndrome 1 ALMS1 7840 NM_015120 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214708_at BG484314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG484314 /FEA=EST /DB_XREF=gi:13416593 /DB_XREF=est:602504947F1 /CLONE=IMAGE:4618547 /UG=Hs.95011 syntrophin, beta 1 (dystrophin-associated protein A1, 59kD, basic component 1) BG484314 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) SNTB1 6641 NM_021021 /// XM_005251031 /// XM_005251032 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 214709_s_at Z22551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22551.1 /DEF=H.sapiens kinectin gene. /FEA=mRNA /GEN=kinectin /PROD=156 kDa Protein /DB_XREF=gi:296163 /UG=Hs.211577 kinectin 1 (kinesin receptor) Z22551 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_001271014 /// NM_004986 /// NM_182926 /// NR_073128 /// NR_073129 /// XM_006720138 /// XM_006720139 /// XM_006720140 /// XM_006720141 0007018 // microtubule-based movement // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0019894 // kinesin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214710_s_at BE407516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE407516 /FEA=EST /DB_XREF=gi:9343966 /DB_XREF=est:601300355F1 /CLONE=IMAGE:3630517 /UG=Hs.23960 cyclin B1 BE407516 cyclin B1 CCNB1 891 NM_031966 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000236 // mitotic prometaphase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007080 // mitotic metaphase plate congression // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0033129 // positive regulation of histone phosphorylation // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043148 // mitotic spindle stabilization // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046680 // response to DDT // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // traceable author statement /// 0051987 // positive regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060623 // regulation of chromosome condensation // inferred from electronic annotation /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype /// 0071283 // cellular response to iron(III) ion // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0000942 // condensed nuclear chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005113 // patched binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 214711_at BE568184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE568184 /FEA=EST /DB_XREF=gi:9811904 /DB_XREF=est:601341722F1 /CLONE=IMAGE:3683860 /UG=Hs.200400 Human DNA sequence from BAC 15E1 on chromosome 12. Contains Cytochrome C Oxidase Polypeptide VIa-liver precursor gene, 60S ribosomal protein L31 pseudogene, pre-mRNA splicing factor SRp30c gene, two putative genes, ESTs, STSs and putative CpG islands BE568184 glutamyl-tRNA(Gln) amidotransferase, subunit C GATC 283459 NM_176818 /// NR_033684 0006412 // translation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 214712_at AK023827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023827.1 /DEF=Homo sapiens cDNA FLJ13765 fis, clone PLACE4000128, weakly similar to Mus musculus putative transcription factor mRNA. /FEA=mRNA /DB_XREF=gi:10435879 /UG=Hs.194637 BANP homolog, SMAR1 homolog AK023827 sorting nexin 29 pseudogene 2 SNX29P2 440352 NR_002939 214713_at AI703162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI703162 /FEA=EST /DB_XREF=gi:4991062 /DB_XREF=est:wd92e08.x1 /CLONE=IMAGE:2339078 /UG=Hs.159471 ZAP3 protein AI703162 YLP motif containing 1 YLPM1 56252 NM_019589 /// XM_005267860 /// XR_245704 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032204 // regulation of telomere maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214714_at AK022360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022360.1 /DEF=Homo sapiens cDNA FLJ12298 fis, clone MAMMA1001837, weakly similar to ZINC FINGER PROTEIN 29. /FEA=mRNA /DB_XREF=gi:10433741 /UG=Hs.284168 hypothetical protein MPMGp800M05499Q3 AK022360 zinc finger protein 394 ZNF394 84124 NM_032164 /// XM_005250638 /// XM_005250639 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214715_x_at AK024789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024789.1 /DEF=Homo sapiens cDNA: FLJ21136 fis, clone CAS07469. /FEA=mRNA /DB_XREF=gi:10437175 /UG=Hs.206882 Homo sapiens mRNA for FLJ00032 protein, partial cds AK024789 zinc finger protein 160 ZNF160 90338 NM_001102603 /// NM_033288 /// NM_198893 /// XM_005259378 /// XM_005259379 /// XM_005259380 /// XM_006723461 /// XM_006723462 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214716_at AW504018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW504018 /FEA=EST /DB_XREF=gi:7141685 /DB_XREF=est:UI-HF-BN0-alh-f-03-0-UI.r1 /CLONE=IMAGE:3079804 /UG=Hs.20137 hypothetical protein DKFZp434P0116 AW504018 BMP2 inducible kinase BMP2K 55589 NM_017593 /// NM_198892 /// XM_005263117 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from physical interaction /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // inferred from electronic annotation 214717_at AL137534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137534.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H1419 (from clone DKFZp434H1419); partial cds. /FEA=mRNA /GEN=DKFZp434H1419 /PROD=hypothetical protein /DB_XREF=gi:6808209 /UG=Hs.56876 Homo sapiens mRNA; cDNA DKFZp434H1419 (from clone DKFZp434H1419); partial cds AL137534 DKFZp434H1419 PKI55 150967 NM_001199924 /// NR_037701 214718_at AK026142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026142.1 /DEF=Homo sapiens cDNA: FLJ22489 fis, clone HRC10951. /FEA=mRNA /DB_XREF=gi:10438897 /UG=Hs.21145 hypothetical protein FLJ22489 AK026142 GATA zinc finger domain containing 1 GATAD1 57798 NM_021167 /// NR_052016 /// XR_428181 /// XR_428182 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214719_at AK026720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026720.1 /DEF=Homo sapiens cDNA: FLJ23067 fis, clone LNG04993. /FEA=mRNA /DB_XREF=gi:10439638 /UG=Hs.117167 Homo sapiens cDNA: FLJ23067 fis, clone LNG04993 AK026720 solute carrier family 46, member 3 SLC46A3 283537 NM_001135919 /// NM_181785 /// XM_005266361 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 214720_x_at BF981643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF981643 /FEA=EST /DB_XREF=gi:12384455 /DB_XREF=est:602305961F1 /CLONE=IMAGE:4397295 /UG=Hs.79844 DKFZP564M1416 protein BF981643 septin 10 SEPT10 151011 NM_144710 /// NM_178584 /// NR_047585 /// XM_006712317 /// XM_006712318 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 214721_x_at AL162074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162074.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762L106 (from clone DKFZp762L106); partial cds. /FEA=mRNA /GEN=DKFZp762L106 /PROD=hypothetical protein /DB_XREF=gi:7328153 /UG=Hs.3903 Cdc42 effector protein 4; binder of Rho GTPases 4 AL162074 CDC42 effector protein (Rho GTPase binding) 4 CDC42EP4 23580 NM_012121 /// XM_005257182 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 214722_at AW516297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW516297 /FEA=EST /DB_XREF=gi:7154379 /DB_XREF=est:xt64d08.x1 /CLONE=IMAGE:2791215 /UG=Hs.323231 Homo sapiens cDNA FLJ11946 fis, clone HEMBB1000709 AW516297 notch 2 N-terminal like NOTCH2NL 388677 NM_203458 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 214723_x_at AB046861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046861.1 /DEF=Homo sapiens mRNA for KIAA1641 protein, partial cds. /FEA=mRNA /GEN=KIAA1641 /PROD=KIAA1641 protein /DB_XREF=gi:10047358 /UG=Hs.44566 KIAA1641 protein AB046861 ankyrin repeat domain 36 ANKRD36 375248 NM_001164315 /// NM_198555 /// XM_005263937 /// XM_005263938 /// XM_006712514 /// XM_006712515 /// XM_006712516 /// XM_006712517 /// XR_427086 0005515 // protein binding // inferred from electronic annotation 214724_at AF070621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070621.1 /DEF=Homo sapiens clone 24760 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283887 /UG=Hs.61408 Homo sapiens mRNA for KIAA1735 protein, partial cds AF070621 DIX domain containing 1 DIXDC1 85458 NM_001037954 /// NM_001278542 /// NM_033425 /// XM_005277726 /// XM_005277727 /// XM_005277728 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021695 // cerebellar cortex development // not recorded /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021869 // forebrain ventricular zone progenitor cell division // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030900 // forebrain development // not recorded /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0043010 // camera-type eye development // not recorded /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // not recorded /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // not recorded /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // not recorded /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // not recorded 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // not recorded /// 0043015 // gamma-tubulin binding // inferred from direct assay 214725_at BE968773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE968773 /FEA=EST /DB_XREF=gi:10579478 /DB_XREF=est:601649956F1 /CLONE=IMAGE:3933925 /UG=Hs.41185 Homo sapiens mRNA; cDNA DKFZp564O1262 (from clone DKFZp564O1262) BE968773 somatomedin B and thrombospondin, type 1 domain containing SBSPON 157869 NM_153225 /// XM_005251178 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation 214726_x_at AL556041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL556041 /FEA=EST /DB_XREF=gi:12898348 /DB_XREF=est:AL556041 /CLONE=CS0DK010YL13 (5 prime) /UG=Hs.183706 adducin 1 (alpha) AL556041 adducin 1 (alpha) ADD1 118 NM_001119 /// NM_001286645 /// NM_014189 /// NM_014190 /// NM_176801 /// XM_005247933 /// XM_005247934 /// XM_005247935 /// XM_005247936 /// XM_005247937 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 214727_at X95152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95152 /DEF=H.sapiens brca2 gene exon 2 (and joined coding region) /FEA=mRNA /DB_XREF=gi:1171546 /UG=Hs.34012 breast cancer 2, early onset X95152 breast cancer 2, early onset BRCA2 675 NM_000059 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000910 // cytokinesis // inferred from direct assay /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043009 // chordate embryonic development // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0048478 // replication fork protection // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0033593 // BRCA2-MAGE-D1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010484 // H3 histone acetyltransferase activity // inferred from direct assay /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0043015 // gamma-tubulin binding // inferred from physical interaction 214728_x_at AK026573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026573.1 /DEF=Homo sapiens cDNA: FLJ22920 fis, clone KAT06686, highly similar to HSU29175 Human transcriptional activator (BRG1) mRNA. /FEA=mRNA /DB_XREF=gi:10439456 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AK026573 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 214729_at AA400421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA400421 /FEA=EST /DB_XREF=gi:2054292 /DB_XREF=est:zu69h09.r1 /CLONE=IMAGE:743297 /UG=Hs.55896 Homo sapiens PAC clone RP5-978E18 from 7p21 AA400421 TWIST neighbor TWISTNB 221830 NM_001002926 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0001054 // RNA polymerase I activity // not recorded /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation 214730_s_at AK025457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025457.1 /DEF=Homo sapiens cDNA: FLJ21804 fis, clone HEP00746, highly similar to HSU64791 Human Golgi membrane sialoglycoprotein MG160 (GLG1) mRNA. /FEA=mRNA /DB_XREF=gi:10437977 /UG=Hs.78979 Golgi apparatus protein 1 AK025457 golgi glycoprotein 1 GLG1 2734 NM_001145666 /// NM_001145667 /// NM_012201 /// NR_027264 /// NR_027265 0007596 // blood coagulation // traceable author statement /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060349 // bone morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 214731_at AB037854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037854.1 /DEF=Homo sapiens mRNA for KIAA1433 protein, partial cds. /FEA=mRNA /GEN=KIAA1433 /PROD=KIAA1433 protein /DB_XREF=gi:7243246 /UG=Hs.23921 hypothetical protein DKFZp547A023 AB037854 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0032410 // negative regulation of transporter activity // inferred from mutant phenotype /// 0034763 // negative regulation of transmembrane transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 214732_at AU121035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU121035 /FEA=EST /DB_XREF=gi:10936270 /DB_XREF=est:AU121035 /CLONE=HEMBB1001936 /UG=Hs.2021 Sp1 transcription factor AU121035 Sp1 transcription factor SP1 6667 NM_001251825 /// NM_003109 /// NM_138473 /// XM_006719570 /// XM_006719571 0001503 // ossification // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0030219 // megakaryocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from electronic annotation /// 0035326 // enhancer binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from physical interaction 214733_s_at AL031427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031427 /DEF=Human DNA sequence from clone 167A19 on chromosome 1p32.1-33. Contains three genes for novel proteins, the DIO1 gene for type I iodothyronine deiodinase (EC 3.8.1.4, TXDI1, ITDI1) and an HNRNP A3 (Heterogenous Nuclear Ribonucleoprotein A3, FBRNP) ... /FEA=mRNA_6 /DB_XREF=gi:4835258 /UG=Hs.11923 hypothetical protein AL031427 Yip1 domain family, member 1 YIPF1 54432 NM_018982 /// NR_036639 /// NR_036640 /// XR_426612 /// XR_426613 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation 214734_at AB014524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014524.1 /DEF=Homo sapiens mRNA for KIAA0624 protein, partial cds. /FEA=mRNA /GEN=KIAA0624 /PROD=KIAA0624 protein /DB_XREF=gi:3327061 /UG=Hs.138380 KIAA0624 protein AB014524 exophilin 5 EXPH5 23086 NM_001144763 /// NM_001144765 /// NM_015065 /// XM_005271461 /// XM_005271462 /// XM_005271463 0003334 // keratinocyte development // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction 214735_at AW166711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW166711 /FEA=EST /DB_XREF=gi:6398236 /DB_XREF=est:xg27h02.x1 /CLONE=IMAGE:2628819 /UG=Hs.185140 KIAA0403 protein AW166711 interaction protein for cytohesin exchange factors 1 IPCEF1 26034 NM_001130699 /// NM_001130700 /// NM_015553 /// XM_005266919 /// XM_005266920 /// XM_005266921 /// XM_005266922 /// XM_005266923 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0015671 // oxygen transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004601 // peroxidase activity // inferred from sequence or structural similarity /// 0005344 // oxygen transporter activity // non-traceable author statement 214736_s_at BE898639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE898639 /FEA=EST /DB_XREF=gi:10365322 /DB_XREF=est:601681587F1 /CLONE=IMAGE:3951933 /UG=Hs.183706 adducin 1 (alpha) BE898639 adducin 1 (alpha) ADD1 118 NM_001119 /// NM_001286645 /// NM_014189 /// NM_014190 /// NM_176801 /// XM_005247933 /// XM_005247934 /// XM_005247935 /// XM_005247936 /// XM_005247937 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred by curator /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008290 // F-actin capping protein complex // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 214737_x_at AV725195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV725195 /FEA=EST /DB_XREF=gi:10830339 /DB_XREF=est:AV725195 /CLONE=HTCBCH08 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) AV725195 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214738_s_at BE792298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE792298 /FEA=EST /DB_XREF=gi:10213496 /DB_XREF=est:601585788F1 /CLONE=IMAGE:3940100 /UG=Hs.306533 Untitled BE792298 NIMA-related kinase 9 NEK9 91754 NM_033116 /// XM_005268208 /// XM_005268209 /// XM_006720303 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214739_at AI357539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357539 /FEA=EST /DB_XREF=gi:4109160 /DB_XREF=est:qu20a12.x1 /CLONE=IMAGE:1965310 /UG=Hs.289038 Homo sapiens cDNA: FLJ20994 fis, clone CAE02453 AI357539 leucine-rich repeats and calponin homology (CH) domain containing 3 LRCH3 84859 NM_032773 /// XM_005269362 /// XM_005269363 /// XM_005269365 /// XM_005269367 /// XM_006713791 /// XM_006713792 /// XM_006713793 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 214740_at BE676209 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE676209 /FEA=EST /DB_XREF=gi:10036750 /DB_XREF=est:7f25c02.x1 /CLONE=IMAGE:3295682 /UG=Hs.80475 polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) BE676209 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa /// polymerase (RNA) II (DNA directed) polypeptide J2 /// polymerase (RNA) II (DNA directed) polypeptide J3 /// uroplakin 3B-like POLR2J /// POLR2J2 /// POLR2J3 /// UPK3BL 5439 /// 246721 /// 548644 /// 100134938 NM_001015884 /// NM_001097615 /// NM_001114403 /// NM_006234 /// NM_032958 /// NM_032959 /// NM_145325 /// XM_005250452 /// XM_006716032 /// XM_006716033 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 214741_at AW968301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW968301 /FEA=EST /DB_XREF=gi:8158036 /DB_XREF=est:EST380271 /UG=Hs.78743 zinc finger protein 131 (clone pHZ-10) AW968301 uncharacterized LOC100506639 /// zinc finger protein 131 LOC100506639 /// ZNF131 7690 /// 100506639 NM_003432 /// NR_102752 /// XM_005248359 /// XM_005248360 /// XM_005248361 /// XM_005248362 /// XM_005248363 /// XM_005248365 /// XM_005248367 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214742_at AB029041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029041.1 /DEF=Homo sapiens mRNA for KIAA1118 protein, partial cds. /FEA=mRNA /GEN=KIAA1118 /PROD=KIAA1118 protein /DB_XREF=gi:5689572 /UG=Hs.209646 KIAA1118 protein AB029041 centrosomal protein 131kDa CEP131 22994 NM_001009811 /// NM_014984 /// XM_005257174 /// XM_005257176 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 214743_at BE046521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE046521 /FEA=EST /DB_XREF=gi:8363574 /DB_XREF=est:hn48g06.x2 /CLONE=IMAGE:3026938 /UG=Hs.147049 cut (Drosophila)-like 1 (CCAAT displacement protein) BE046521 cut-like homeobox 1 CUX1 1523 NM_001202543 /// NM_001202544 /// NM_001202545 /// NM_001202546 /// NM_001913 /// NM_181500 /// NM_181552 /// XM_005250150 /// XM_005250151 /// XM_005250154 /// XM_006715854 /// XM_006715855 /// XM_006715856 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000301 // retrograde transport, vesicle recycling within Golgi // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay 214744_s_at AK021960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021960.1 /DEF=Homo sapiens cDNA FLJ11898 fis, clone HEMBA1007322. /FEA=mRNA /DB_XREF=gi:10433269 /UG=Hs.313509 Homo sapiens cDNA FLJ11898 fis, clone HEMBA1007322 AK021960 ribosomal protein L23 /// small nucleolar RNA, H/ACA box 21 RPL23 /// SNORA21 9349 /// 619505 NM_000978 /// NR_002576 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006610 // ribosomal protein import into nucleus // non-traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214745_at AW665865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW665865 /FEA=EST /DB_XREF=gi:7458414 /DB_XREF=est:hi94h02.x1 /CLONE=IMAGE:2979987 /UG=Hs.193143 KIAA1069 protein AW665865 phospholipase C, eta 1 PLCH1 23007 NM_001130960 /// NM_001130961 /// NM_014996 /// XM_005247238 /// XM_005247239 /// XM_006713541 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050429 // calcium-dependent phospholipase C activity // inferred from direct assay 214746_s_at BE549732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE549732 /FEA=EST /DB_XREF=gi:9791424 /DB_XREF=est:7b38a04.x1 /CLONE=IMAGE:3230478 /UG=Hs.112158 Homo sapiens PAC clone RP4-751H13 from 7q35-qter BE549732 zinc finger protein 467 ZNF467 168544 NM_207336 /// XM_005249959 /// XM_005249960 /// XM_005249961 /// XM_006715864 /// XM_006715865 /// XM_006715866 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214747_at AK022892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022892.1 /DEF=Homo sapiens cDNA FLJ12830 fis, clone NT2RP2003073. /FEA=mRNA /DB_XREF=gi:10434549 /UG=Hs.123158 Homo sapiens cDNA FLJ12830 fis, clone NT2RP2003073 AK022892 zinc finger, BED-type containing 4 ZBED4 9889 NM_014838 /// XM_005261875 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 214748_at U50529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U50529.1 /DEF=Human BRCA2 region, mRNA sequence CG016. /FEA=mRNA /DB_XREF=gi:1531600 /UG=Hs.112434 Novel human gene mapping to chomosome 13 U50529 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 214749_s_at AK000818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000818.1 /DEF=Homo sapiens cDNA FLJ20811 fis, clone ADSE01435. /FEA=mRNA /DB_XREF=gi:7021128 /UG=Hs.83530 hypothetical protein AK000818 armadillo repeat containing, X-linked 6 ARMCX6 54470 NM_001009584 /// NM_001184768 /// NM_019007 /// NR_033669 /// NR_033670 /// XM_006724665 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214750_at L13197 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13197.1 /DEF=Human (clone D21S418E) pregnancy-associated plasma protein A (PAPP-A) gene, 5 UTR. /FEA=mRNA /DB_XREF=gi:1480207 /UG=Hs.75874 pregnancy-associated plasma protein A L13197 placenta-specific 4 PLAC4 191585 NM_182832 0019028 // viral capsid // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 214751_at BE541042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE541042 /FEA=EST /DB_XREF=gi:9769786 /DB_XREF=est:601064390F1 /CLONE=IMAGE:3450599 /UG=Hs.23240 Homo sapiens cDNA FLJ13496 fis, clone PLACE1004471, weakly similar to ZINC FINGER PROTEIN 83 BE541042 zinc finger protein 468 ZNF468 90333 NM_001008801 /// NM_001277120 /// NM_199132 /// NR_102299 /// NR_102300 /// NR_102301 /// XM_006723459 /// XM_006723460 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214752_x_at AI625550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI625550 /FEA=EST /DB_XREF=gi:4650481 /DB_XREF=est:ty57d06.x1 /CLONE=IMAGE:2283179 /UG=Hs.195464 filamin A, alpha (actin-binding protein-280) AI625550 filamin A, alpha FLNA 2316 NM_001110556 /// NM_001456 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from direct assay /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred by curator /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097440 // apical dendrite // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from direct assay /// 0031267 // small GTPase binding // inferred from direct assay /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 214753_at AW084068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW084068 /FEA=EST /DB_XREF=gi:6039220 /DB_XREF=est:xc26c06.x1 /CLONE=IMAGE:2585386 /UG=Hs.110630 Human BRCA2 region, mRNA sequence CG006 AW084068 NEDD4 binding protein 2-like 2 /// Human BRCA2 region, mRNA sequence CG006. N4BP2L2 /// U50535 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 214754_at AB007861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007861.1 /DEF=Homo sapiens KIAA0401 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0401 /DB_XREF=gi:2662082 /UG=Hs.17803 KIAA0401 protein AB007861 tet methylcytosine dioxygenase 3 TET3 200424 NM_001287491 /// NM_144993 /// XM_005264187 /// XM_006711963 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0044727 // DNA demethylation of male pronucleus // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from sequence or structural similarity /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0070579 // methylcytosine dioxygenase activity // inferred from sequence or structural similarity 214755_at AK022632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022632.1 /DEF=Homo sapiens cDNA FLJ12570 fis, clone NT2RM4000895. /FEA=mRNA /DB_XREF=gi:10434135 /UG=Hs.142076 Homo sapiens cDNA FLJ12570 fis, clone NT2RM4000895 AK022632 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 UAP1L1 91373 NM_207309 /// XM_006717317 0008152 // metabolic process // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 214756_x_at AB017004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB017004.1 /DEF=Homo sapiens PMS2L13 mRNA, partial cds. /FEA=mRNA /GEN=PMS2L13 /DB_XREF=gi:4239949 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 AB017004 postmeiotic segregation increased 2 pseudogene 1 PMS2P1 5379 NM_005394 /// NR_003613 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 214757_at BG178274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG178274 /FEA=EST /DB_XREF=gi:12684977 /DB_XREF=est:602330318F1 /CLONE=IMAGE:4431676 /UG=Hs.278895 postmeiotic segregation increased 2-like 5 BG178274 postmeiotic segregation increased 2-like 2 pseudogene PMS2L2 5380 NR_003614 0006298 // mismatch repair // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation 214758_at AL080157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080157.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K114 (from clone DKFZp434K114). /FEA=mRNA /GEN=DKFZp434K114 /PROD=hypothetical protein /DB_XREF=gi:5262616 /UG=Hs.6107 DKFZP434K114 protein AL080157 DDB1 and CUL4 associated factor 4 DCAF4 26094 NM_001163508 /// NM_001163509 /// NM_015604 /// NM_181340 /// NM_181341 /// XM_005267522 /// XM_005267523 /// XM_005267524 /// XM_005267525 /// XM_005267526 /// XM_006720113 /// XM_006720114 /// XM_006720115 /// XR_245678 /// XR_429310 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 214759_at AL583911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583911.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761K0722 (from clone DKFZp761K0722). /FEA=mRNA /GEN=DKFZp761K0722 /PROD=hypothetical protein /DB_XREF=gi:13093774 /UG=Hs.295071 Homo sapiens mRNA; cDNA DKFZp761K0722 (from clone DKFZp761K0722) AL583911 Wilms tumor 1 associated protein WTAP 9589 NM_001270531 /// NM_001270532 /// NM_001270533 /// NM_004906 /// NM_152857 /// NM_152858 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0080009 // mRNA methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 214760_at AL049942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049942.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F1422 (from clone DKFZp564F1422). /FEA=mRNA /GEN=DKFZp564F1422 /PROD=hypothetical protein /DB_XREF=gi:4884185 /UG=Hs.139240 DKFZP564F1422 protein AL049942 zinc finger protein 337 ZNF337 26152 NM_001290261 /// NM_015655 /// XM_005260702 /// XM_006723558 /// XM_006723559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214761_at AW149417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149417 /FEA=EST /DB_XREF=gi:6197313 /DB_XREF=est:xf36h07.x1 /CLONE=IMAGE:2620189 /UG=Hs.137168 OLF-1EBF associated zinc finger gene AW149417 zinc finger protein 423 ZNF423 23090 NM_001271620 /// NM_015069 /// XM_005255855 /// XM_005255856 /// XM_005255857 /// XM_006721171 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214762_at BF340635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF340635 /FEA=EST /DB_XREF=gi:11287195 /DB_XREF=est:602037609F1 /CLONE=IMAGE:4185482 /UG=Hs.249227 Homo sapiens DNA, cosmid clones TN62 and TN82 BF340635 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 ATP6V1G2 534 NM_001204078 /// NM_130463 /// NM_138282 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation 214763_at AK023937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023937.1 /DEF=Homo sapiens cDNA FLJ13875 fis, clone THYRO1001374, weakly similar to CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE (EC 3.1.2.2). /FEA=mRNA /DB_XREF=gi:10436031 /UG=Hs.234786 KIAA0707 protein AK023937 acyl-CoA thioesterase 11 ACOT11 26027 NM_015547 /// NM_147161 0006631 // fatty acid metabolic process // non-traceable author statement /// 0009266 // response to temperature stimulus // inferred from sequence or structural similarity /// 0009409 // response to cold // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // traceable author statement 214764_at AW029169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW029169 /FEA=EST /DB_XREF=gi:5887925 /DB_XREF=est:wx06g01.x1 /CLONE=IMAGE:2542896 /UG=Hs.158241 KIAA0507 protein AW029169 ribosomal RNA processing 15 homolog (S. cerevisiae) RRP15 51018 NM_016052 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 214765_s_at AK024677 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024677.1 /DEF=Homo sapiens cDNA: FLJ21024 fis, clone CAE06651, highly similar to HUMPLT Human LTR mRNA. /FEA=mRNA /DB_XREF=gi:10437016 /UG=Hs.264330 N-acylsphingosine amidohydrolase (acid ceramidase)-like AK024677 N-acylethanolamine acid amidase NAAA 27163 NM_001042402 /// NM_014435 /// XM_005262920 /// XM_005262921 /// XM_005262923 /// XM_005262924 /// XM_005262925 /// XM_006714178 /// XM_006714179 /// XM_006714180 /// XM_006714181 /// XR_427542 0006629 // lipid metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from direct assay 214766_s_at AL080144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080144.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N093 (from clone DKFZp434N093); partial cds. /FEA=mRNA /GEN=DKFZp434N093 /PROD=hypothetical protein /DB_XREF=gi:5262592 /UG=Hs.33363 DKFZP434N093 protein AL080144 AT hook containing transcription factor 1 AHCTF1 25909 NM_015446 /// XM_006711758 /// XM_006711759 /// XR_426916 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 214767_s_at AL551046 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL551046 /FEA=EST /DB_XREF=gi:12888616 /DB_XREF=est:AL551046 /CLONE=CS0DI066YN13 (5 prime) /UG=Hs.332742 Human DNA from chromosome 19-specific cosmid F25965, genomic sequence AL551046 heat shock protein, alpha-crystallin-related, B6 HSPB6 126393 NM_144617 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 214768_x_at BG540628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG540628 /FEA=EST /DB_XREF=gi:13532861 /DB_XREF=est:602570501F1 /CLONE=IMAGE:4694688 /UG=Hs.323936 Human active IgK chain from GM 607, V-kappa-2 region BG540628 immunoglobulin kappa constant /// immunoglobulin kappa variable 2-28 /// /// immunoglobulin kappa variable 2D-28 /// IGKC /// IGKV2-28 /// IGKV2-28 /// IGKV2D-28 /// IGKV2D-28 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214769_at AF052117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052117.1 /DEF=Homo sapiens clone 23809 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360424 /UG=Hs.6932 Homo sapiens clone 23809 mRNA sequence AF052117 chloride channel, voltage-sensitive 4 CLCN4 1183 NM_001256944 /// NM_001830 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 214770_at AI299239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI299239 /FEA=EST /DB_XREF=gi:3958893 /DB_XREF=est:qn33g02.x1 /CLONE=IMAGE:1900082 /UG=Hs.49 macrophage scavenger receptor 1 AI299239 macrophage scavenger receptor 1 MSR1 4481 NM_002445 /// NM_138715 /// NM_138716 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0030301 // cholesterol transport // inferred from sequence or structural similarity /// 0034381 // plasma lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042221 // response to chemical // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from sequence or structural similarity 214771_x_at AK025604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025604.1 /DEF=Homo sapiens cDNA: FLJ21951 fis, clone HEP04968. /FEA=mRNA /DB_XREF=gi:10438172 /UG=Hs.84883 KIAA0864 protein AK025604 myosin phosphatase Rho interacting protein MPRIP 23164 NM_015134 /// NM_201274 /// XM_005256563 /// XM_005256564 /// XM_006721487 /// XM_006721488 /// XM_006721489 /// XM_006721490 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 214772_at H08993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H08993 /FEA=EST /DB_XREF=gi:873815 /DB_XREF=est:yl96e04.r1 /CLONE=IMAGE:45829 /UG=Hs.30660 G2 protein H08993 KIAA1549-like KIAA1549L 25758 NM_012194 /// XM_005252847 /// XM_005252848 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214773_x_at AI983505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983505 /FEA=EST /DB_XREF=gi:5810724 /DB_XREF=est:wt49h12.x1 /CLONE=IMAGE:2510855 /UG=Hs.137576 ribosomal protein L34 pseudogene 1 AI983505 TOR signaling pathway regulator TIPRL 261726 NM_001031800 /// NM_152902 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0034048 // negative regulation of protein phosphatase type 2A activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214774_x_at AK027006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027006.1 /DEF=Homo sapiens cDNA: FLJ23353 fis, clone HEP14321, highly similar to HSU80736 Homo sapiens CAGF9 mRNA. /FEA=mRNA /DB_XREF=gi:10440010 /UG=Hs.110826 trinucleotide repeat containing 9 AK027006 TOX high mobility group box family member 3 TOX3 27324 NM_001080430 /// NM_001146188 /// XM_005255892 /// XM_005255893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0034056 // estrogen response element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 214775_at AW139448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139448 /FEA=EST /DB_XREF=gi:6144166 /DB_XREF=est:UI-H-BI1-adq-h-05-0-UI.s1 /CLONE=IMAGE:2717816 /UG=Hs.101761 KIAA0341 protein AW139448 NEDD4 binding protein 3 N4BP3 23138 NM_015111 /// XM_006714834 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214776_x_at AA777793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA777793 /FEA=EST /DB_XREF=gi:2837272 /DB_XREF=est:zi99g02.s1 /CLONE=IMAGE:448946 /UG=Hs.137580 xylulokinase (H. influenzae) homolog AA777793 xylulokinase homolog (H. influenzae) XYLB 9942 NM_005108 /// XM_006713448 /// XM_006713449 /// XM_006713450 /// XR_245171 0005975 // carbohydrate metabolic process // traceable author statement /// 0005997 // xylulose metabolic process // inferred from direct assay /// 0005998 // xylulose catabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042732 // D-xylose metabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004856 // xylulokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 214777_at BG482805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG482805 /FEA=EST /DB_XREF=gi:13415084 /DB_XREF=est:602502595F1 /CLONE=IMAGE:4616255 /UG=Hs.248756 H.sapiens rearranged gene for kappa immunoglobulin subgroup V kappa IV BG482805 Parts of antibodies, mostly variable regions. /// immunoglobulin kappa constant /// immunoglobulin kappa variable 4-1 /// abParts /// IGKC /// IGKV4-1 /// IGKV4-1 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214778_at AB011541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011541.1 /DEF=Homo sapiens mRNA for MEGF8, partial cds. /FEA=mRNA /GEN=MEGF8 /PROD=MEGF8 /DB_XREF=gi:3449307 /UG=Hs.158200 EGF-like-domain, multiple 4 AB011541 multiple EGF-like-domains 8 MEGF8 1954 NM_001271938 /// NM_001410 /// NM_178121 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0042074 // cell migration involved in gastrulation // inferred from mutant phenotype /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0055113 // epiboly involved in gastrulation with mouth forming second // inferred from mutant phenotype /// 0060971 // embryonic heart tube left/right pattern formation // inferred from sequence or structural similarity /// 0060972 // left/right pattern formation // inferred from mutant phenotype /// 0061371 // determination of heart left/right asymmetry // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from sequence or structural similarity /// 0097094 // craniofacial suture morphogenesis // inferred from mutant phenotype /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214779_s_at R51077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R51077 /FEA=EST /DB_XREF=gi:812979 /DB_XREF=est:yg64c05.s1 /CLONE=IMAGE:37496 /UG=Hs.22129 hypothetical protein R51077 small G protein signaling modulator 3 SGSM3 27352 NM_015705 /// XM_005261572 /// XM_005261573 /// XM_005261574 /// XM_005261575 /// XM_005261577 /// XM_005261579 /// XR_244369 /// XR_244370 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032483 // regulation of Rab protein signal transduction // inferred from expression pattern /// 0032486 // Rap protein signal transduction // inferred from expression pattern /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from direct assay 214780_s_at AK002201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002201.1 /DEF=Homo sapiens cDNA FLJ11339 fis, clone PLACE1010743, weakly similar to Homo sapiens myosin-IXb splice variant mRNA. /FEA=mRNA /DB_XREF=gi:7023929 /UG=Hs.159629 myosin IXB AK002201 myosin IXB MYO9B 4650 NM_001130065 /// NM_004145 /// XM_005259915 /// XM_006722755 /// XM_006722756 /// XM_006722757 /// XM_006722758 0002548 // monocyte chemotaxis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030048 // actin filament-based movement // traceable author statement /// 0032011 // ARF protein signal transduction // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0032433 // filopodium tip // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 214781_at AL162013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162013.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761P19121 (from clone DKFZp761P19121); partial cds. /FEA=mRNA /GEN=DKFZp761P19121 /PROD=hypothetical protein /DB_XREF=gi:7328040 /UG=Hs.322844 plexin A1 AL162013 0007165 // signal transduction // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0017154 // semaphorin receptor activity // inferred from electronic annotation 214782_at AU155105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU155105 /FEA=EST /DB_XREF=gi:11016626 /DB_XREF=est:AU155105 /CLONE=OVARC1001000 /UG=Hs.301348 Homo sapiens cDNA FLJ13271 fis, clone OVARC1001000 AU155105 cortactin CTTN 2017 NM_001184740 /// NM_005231 /// NM_138565 /// XM_006718447 /// XM_006718448 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214783_s_at BG177920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG177920 /FEA=EST /DB_XREF=gi:12684623 /DB_XREF=est:602327839F1 /CLONE=IMAGE:4429256 /UG=Hs.75510 annexin A11 BG177920 annexin A11 ANXA11 311 NM_001157 /// NM_001278407 /// NM_001278408 /// NM_001278409 /// NM_145868 /// NM_145869 /// XM_005269741 /// XM_005269742 /// XM_006717813 /// XM_006717814 0006909 // phagocytosis // inferred from expression pattern /// 0007049 // cell cycle // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 214784_x_at BE966299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966299 /FEA=EST /DB_XREF=gi:11771566 /DB_XREF=est:601660539R1 /CLONE=IMAGE:3906248 /UG=Hs.70500 KIAA0370 protein BE966299 exportin 6 XPO6 23214 NM_001270940 /// NM_015171 /// XM_005255195 /// XM_005255197 /// XM_005255198 /// XM_005255199 /// XM_005255200 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay 214785_at AB023203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023203.1 /DEF=Homo sapiens mRNA for KIAA0986 protein, partial cds. /FEA=mRNA /GEN=KIAA0986 /PROD=KIAA0986 protein /DB_XREF=gi:4589615 /UG=Hs.53542 KIAA0986 protein AB023203 vacuolar protein sorting 13 homolog A (S. cerevisiae) VPS13A 23230 NM_001018037 /// NM_001018038 /// NM_015186 /// NM_033305 /// XR_242579 /// XR_242580 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008104 // protein localization // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0031045 // dense core granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214786_at AA361361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA361361 /FEA=EST /DB_XREF=gi:2013679 /DB_XREF=est:EST70631 /UG=Hs.298727 mitogen-activated protein kinase kinase kinase 1 AA361361 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase MAP3K1 4214 NM_005921 /// XM_005248519 /// XM_005248520 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // non-traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006915 // apoptotic process // not recorded /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // not recorded /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0061029 // eyelid development in camera-type eye // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214787_at BE268538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE268538 /FEA=EST /DB_XREF=gi:9142145 /DB_XREF=est:601125471F1 /CLONE=IMAGE:3345232 /UG=Hs.135202 c-myc promoter-binding protein BE268538 DENN/MADD domain containing 4A DENND4A 10260 NM_001144823 /// NM_005848 /// XM_005254119 /// XM_005254120 /// XM_005254121 /// XM_005254122 /// XM_006720371 /// XM_006720372 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 214788_x_at AA731713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA731713 /FEA=EST /DB_XREF=gi:2752602 /DB_XREF=est:nw70c06.s1 /CLONE=IMAGE:1251946 /UG=Hs.120228 KIAA0749 protein AA731713 dendrin DDN 23109 NM_015086 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay /// 0043204 // perikaryon // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214789_x_at AA524274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA524274 /FEA=EST /DB_XREF=gi:2265202 /DB_XREF=est:ng34d08.s1 /CLONE=IMAGE:936687 /UG=Hs.155160 Splicing factor, arginineserine-rich, 46kD AA524274 serine/arginine-rich splicing factor 8 SRSF8 10929 NM_032102 /// NR_103726 /// XR_428967 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214790_at AK001406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001406.1 /DEF=Homo sapiens cDNA FLJ10544 fis, clone NT2RP2001601, highly similar to Homo sapiens mRNA for KIAA0797 protein. /FEA=mRNA /DB_XREF=gi:7022642 /UG=Hs.27197 SUMO-1-specific protease AK001406 SUMO1/sentrin specific peptidase 6 SENP6 26054 NM_001100409 /// NM_015571 /// XM_006715457 /// XR_241847 0006508 // proteolysis // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from mutant phenotype /// 0070646 // protein modification by small protein removal // inferred from direct assay /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from mutant phenotype 214791_at AK023116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023116.1 /DEF=Homo sapiens cDNA FLJ13054 fis, clone NT2RP3001527, highly similar to Human Sp140 protein (Sp140) mRNA. /FEA=mRNA /DB_XREF=gi:10434889 /UG=Hs.158761 Homo sapiens cDNA FLJ13054 fis, clone NT2RP3001527, highly similar to Human Sp140 protein (Sp140) mRNA AK023116 SP140 nuclear body protein-like SP140L 93349 NM_138402 /// XM_006712854 /// XM_006712855 /// XM_006712856 /// XM_006712857 /// XM_006712858 /// XM_006712859 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214792_x_at AI955119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI955119 /FEA=EST /DB_XREF=gi:5747429 /DB_XREF=est:wx30b04.x1 /CLONE=IMAGE:2545135 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) AI955119 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 /// XM_005256775 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030667 // secretory granule membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 214793_at X93921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X93921.1 /DEF=H.sapiens mRNA for protein-tyrosine-phosphatase (tissue type: testis). /FEA=mRNA /GEN=pyst2 /PROD=protein-tyrosine-phosphatase /DB_XREF=gi:1418935 /UG=Hs.296938 dual specificity phosphatase 7 X93921 dual specificity phosphatase 7 DUSP7 1849 NM_001947 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay 214794_at BF669264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF669264 /FEA=EST /DB_XREF=gi:11943159 /DB_XREF=est:602120534F1 /CLONE=IMAGE:4277696 /UG=Hs.5181 proliferation-associated 2G4, 38kD BF669264 proliferation-associated 2G4, 38kDa PA2G4 5036 NM_006191 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214795_at AL137703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137703.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P1772 (from clone DKFZp564P1772). /FEA=mRNA /DB_XREF=gi:6808066 /UG=Hs.75871 protein kinase C binding protein 1 AL137703 zinc finger, MYND-type containing 8 ZMYND8 23613 NM_001281769 /// NM_001281771 /// NM_001281772 /// NM_001281773 /// NM_001281774 /// NM_001281775 /// NM_001281776 /// NM_001281777 /// NM_001281778 /// NM_001281779 /// NM_001281780 /// NM_001281781 /// NM_001281782 /// NM_001281783 /// NM_001281784 /// NM_012408 /// NM_183047 /// NM_183048 /// XM_005260356 /// XM_005260358 /// XM_005260360 /// XM_005260361 /// XM_005260362 /// XM_005260364 /// XM_005260365 /// XM_005260366 /// XM_005260369 /// XM_005260371 /// XM_005260377 /// XM_006723760 /// XM_006723761 /// XM_006723762 /// XM_006723763 /// XM_006723764 /// XM_006723765 /// XM_006723766 /// XM_006723767 /// XM_006723768 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from sequence or structural similarity 214796_at AW439543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW439543 /FEA=EST /DB_XREF=gi:6974849 /DB_XREF=est:hb86a12.x1 /CLONE=IMAGE:2890078 /UG=Hs.281022 KIAA1456 protein AW439543 KIAA1456 /// uncharacterized LOC101927137 KIAA1456 /// LOC101927137 57604 /// 101927137 NM_001099677 /// NM_020844 /// XM_005273584 /// XM_005273585 /// XM_005273586 /// XM_005273587 /// XM_005273588 /// XM_005273589 /// XM_005273590 /// XM_005273591 /// XM_005273592 /// XM_005273593 /// XM_006716371 /// XM_006716372 /// XM_006716373 /// XM_006716374 /// XM_006716375 /// XM_006716376 /// XM_006716377 /// XR_246167 /// XR_246168 /// XR_246169 /// XR_246170 /// XR_246171 /// XR_246172 /// XR_246173 /// XR_252798 /// XR_252799 /// XR_252800 /// XR_252801 /// XR_252802 /// XR_252803 /// XR_252804 /// XR_428788 /// XR_428789 /// XR_428790 /// XR_428791 /// XR_428792 /// XR_428793 /// XR_428794 /// XR_428795 /// XR_428796 /// XR_432624 /// XR_432625 /// XR_432626 /// XR_432627 /// XR_432628 /// XR_432629 /// XR_432630 /// XR_432631 /// XR_432632 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 214797_s_at BC000281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000281.1 /DEF=Homo sapiens, clone IMAGE:3357514, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3357514) /DB_XREF=gi:12653034 /UG=Hs.2994 PCTAIRE protein kinase 3 BC000281 cyclin-dependent kinase 18 CDK18 5129 NM_002596 /// NM_212502 /// NM_212503 /// XM_006711365 /// XR_426779 /// XR_426780 /// XR_426781 /// XR_426782 /// XR_426783 /// XR_426784 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214798_at AW291664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW291664 /FEA=EST /DB_XREF=gi:6698300 /DB_XREF=est:UI-H-BI2-agn-f-09-0-UI.s1 /CLONE=IMAGE:2725001 /UG=Hs.323439 Homo sapiens cDNA: FLJ21771 fis, clone COLF7779 AW291664 ATPase, Ca++ transporting, type 2C, member 2 ATP2C2 9914 NM_001286527 /// NM_001291454 /// NM_014861 /// XM_006721355 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214799_at AI821777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI821777 /FEA=EST /DB_XREF=gi:5440856 /DB_XREF=est:ag69h02.x5 /CLONE=IMAGE:1128243 /UG=Hs.116604 KIAA0756 protein AI821777 neurofascin NFASC 23114 NM_001005387 /// NM_001005388 /// NM_001005389 /// NM_001160331 /// NM_001160332 /// NM_001160333 /// NM_015090 /// XM_005244977 /// XM_005244985 /// XM_005244986 /// XM_005244989 /// XM_005244991 /// XM_005244992 /// XM_005244993 /// XM_005244996 /// XM_005244997 /// XM_006711226 /// XM_006711227 /// XM_006711228 /// XM_006711229 /// XM_006711230 /// XM_006711231 /// XM_006711232 /// XM_006711233 /// XM_006711234 /// XM_006711235 /// XM_006711236 0002175 // protein localization to paranode region of axon // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045162 // clustering of voltage-gated sodium channels // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0071205 // protein localization to juxtaparanode region of axon // inferred from electronic annotation 0005622 // intracellular // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0033010 // paranodal junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // traceable author statement /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation 214800_x_at R83000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R83000 /FEA=EST /DB_XREF=gi:927844 /DB_XREF=est:yp87a05.s1 /CLONE=IMAGE:194384 /UG=Hs.101025 basic transcription factor 3 R83000 basic transcription factor 3 BTF3 689 NM_001037637 /// NM_001207 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214801_at W88821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W88821 /FEA=EST /DB_XREF=gi:1404293 /DB_XREF=est:zh71d12.r1 /CLONE=IMAGE:417527 /UG=Hs.288924 Homo sapiens cDNA FLJ11392 fis, clone HEMBA1000575 W88821 torsin A interacting protein 2 TOR1AIP2 163590 NM_001199260 /// NM_022347 /// NM_145034 /// XM_005244939 0007029 // endoplasmic reticulum organization // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 214802_at AK022397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022397.1 /DEF=Homo sapiens cDNA FLJ12335 fis, clone MAMMA1002219, highly similar to Rattus norvegicus rexo70 mRNA. /FEA=mRNA /DB_XREF=gi:10433783 /UG=Hs.271273 Homo sapiens cDNA FLJ12335 fis, clone MAMMA1002219, highly similar to Rattus norvegicus rexo70 mRNA AK022397 exocyst complex component 7 EXOC7 23265 NM_001013839 /// NM_001145297 /// NM_001145298 /// NM_001145299 /// NM_001282313 /// NM_001282314 /// NM_015219 /// XM_006721786 /// XM_006721787 /// XM_006721788 /// XM_006721789 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214803_at BF344237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF344237 /FEA=EST /DB_XREF=gi:11291450 /DB_XREF=est:602017491F1 /CLONE=IMAGE:4152983 /UG=Hs.124776 Homo sapiens mRNA; cDNA DKFZp564N1116 (from clone DKFZp564N1116) BF344237 cadherin 6, type 2, K-cadherin (fetal kidney) CDH6 1004 NM_004932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214804_at BF793446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF793446 /FEA=EST /DB_XREF=gi:12098500 /DB_XREF=est:602254922F1 /CLONE=IMAGE:4347388 /UG=Hs.123122 FSH primary response (LRPR1, rat) homolog 1 BF793446 centromere protein I CENPI 2491 NM_006733 /// XM_005262111 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0007548 // sex differentiation // traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034508 // centromere complex assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 214805_at U79273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79273.1 /DEF=Human clone 23933 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710239 /UG=Hs.239483 Human clone 23933 mRNA sequence U79273 eukaryotic translation initiation factor 4A1 /// small nucleolar RNA, H/ACA box 48 /// small nucleolar RNA, H/ACA box 67 /// small nucleolar RNA, C/D box 10 EIF4A1 /// SNORA48 /// SNORA67 /// SNORD10 1973 /// 26781 /// 652965 /// 652966 NM_001204510 /// NM_001416 /// NR_002604 /// NR_002912 /// NR_002918 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214806_at U90030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U90030.1 /DEF=Homo sapiens bicaudal-D (BICD) mRNA, alternatively spliced, partial cds. /FEA=mRNA /GEN=BICD /PROD=bicaudal-D /DB_XREF=gi:2745977 /UG=Hs.164975 Bicaudal D (Drosophila) homolog 1 U90030 bicaudal D homolog 1 (Drosophila) BICD1 636 NM_001003398 /// NM_001714 /// XM_005253465 /// XM_005253466 /// XM_006719134 /// XR_242898 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008298 // intracellular mRNA localization // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from mutant phenotype /// 0033365 // protein localization to organelle // inferred from direct assay /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072385 // minus-end-directed organelle transport along microtubule // inferred from mutant phenotype /// 0072393 // microtubule anchoring at microtubule organizing center // inferred from sequence or structural similarity /// 1900275 // negative regulation of phospholipase C activity // inferred from sequence or structural similarity /// 1900276 // regulation of proteinase activated receptor activity // inferred from sequence or structural similarity /// 1900737 // negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045298 // tubulin complex // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072517 // host cell viral assembly compartment // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0031871 // proteinase activated receptor binding // inferred from sequence or structural similarity /// 0034452 // dynactin binding // inferred from direct assay /// 0045502 // dynein binding // inferred from direct assay 214807_at AI278204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI278204 /FEA=EST /DB_XREF=gi:3900472 /DB_XREF=est:ql83d01.x1 /CLONE=IMAGE:1878913 /UG=Hs.133481 Homo sapiens mRNA; cDNA DKFZp564O0862 (from clone DKFZp564O0862) AI278204 plexin domain containing 2 PLXDC2 84898 NM_001282736 /// NM_032812 0007275 // multicellular organismal development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214808_at AU147851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147851 /FEA=EST /DB_XREF=gi:11009372 /DB_XREF=est:AU147851 /CLONE=MAMMA1001878 /UG=Hs.183819 Homo sapiens cDNA FLJ12304 fis, clone MAMMA1001878 AU147851 RP11-395B7.7 214809_at AL050047 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050047.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566B193 (from clone DKFZp566B193). /FEA=mRNA /DB_XREF=gi:4884286 /UG=Hs.198552 Homo sapiens mRNA; cDNA DKFZp566B193 (from clone DKFZp566B193) AL050047 uncharacterized LOC100294145 LOC100294145 100294145 NR_037177 /// NR_037178 214811_at AB002316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002316.1 /DEF=Human mRNA for KIAA0318 gene, partial cds. /FEA=mRNA /GEN=KIAA0318 /DB_XREF=gi:2224576 /UG=Hs.65746 KIAA0318 protein AB002316 RIMS binding protein 2 RIMBP2 23504 NM_015347 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214812_s_at D80006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D80006.1 /DEF=Human mRNA for KIAA0184 gene, partial cds. /FEA=mRNA /GEN=KIAA0184 /DB_XREF=gi:1136427 /UG=Hs.322903 KIAA0184 protein D80006 MOB kinase activator 1A MOB1A 55233 NM_018221 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214813_at W90796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W90796 /FEA=EST /DB_XREF=gi:1406762 /DB_XREF=est:zh79d08.r1 /CLONE=IMAGE:418287 /UG=Hs.29159 zinc finger protein 75 (D8C6) W90796 zinc finger protein 75D ZNF75D 7626 NM_001185063 /// NM_007131 /// NR_110381 /// XM_005262469 /// XM_005262470 /// XM_005262471 /// XR_426550 /// XR_433782 /// XR_433783 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214814_at BF592058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF592058 /FEA=EST /DB_XREF=gi:11684382 /DB_XREF=est:7n98g09.x1 /CLONE=IMAGE:3572920 /UG=Hs.86405 Homo sapiens mRNA; cDNA DKFZp564P056 (from clone DKFZp564P056) BF592058 YTH domain containing 1 YTHDC1 91746 NM_001031732 /// NM_133370 /// XM_005265706 /// XM_005265707 /// XM_005265708 /// XM_005275637 /// XM_005275638 /// XM_005275639 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214815_at AU136587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU136587 /FEA=EST /DB_XREF=gi:10997126 /DB_XREF=est:AU136587 /CLONE=PLACE1004618 /UG=Hs.287414 transcriptional intermediary factor 1 gamma AU136587 tripartite motif containing 33 TRIM33 51592 NM_015906 /// NM_033020 /// XM_005270936 /// XM_005270937 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 214816_x_at BC003535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003535.1 /DEF=Homo sapiens, clone IMAGE:3609326, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3609326) /DB_XREF=gi:13097635 /UG=Hs.192127 Homo sapiens, clone IMAGE:3609326, mRNA, partial cds BC003535 chromosome 19 open reading frame 40 C19orf40 91442 NM_152266 /// XM_005259393 /// XM_005259394 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214817_at BE783668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE783668 /FEA=EST /DB_XREF=gi:10204866 /DB_XREF=est:601471251F1 /CLONE=IMAGE:3874189 /UG=Hs.175780 KIAA1032 protein BE783668 unc-13 homolog A (C. elegans) UNC13A 23025 NM_001080421 /// XM_006722692 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0016081 // synaptic vesicle docking involved in exocytosis // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0016188 // synaptic vesicle maturation // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214818_at AF007146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007146.1 /DEF=Homo sapiens clone 23686 and 23885 mRNA sequences. /FEA=mRNA /DB_XREF=gi:2852624 /UG=Hs.122075 Homo sapiens clone 23686 and 23885 mRNA sequences AF007146 coiled-coil domain containing 57 CCDC57 284001 NM_152675 /// NM_198082 /// XM_005256345 /// XM_006722279 214819_at BF571239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF571239 /FEA=EST /DB_XREF=gi:11644951 /DB_XREF=est:602077641F1 /CLONE=IMAGE:4251947 /UG=Hs.129892 KIAA0522 protein BF571239 IQ motif and Sec7 domain 2 IQSEC2 23096 NM_001111125 /// NM_001243197 /// NM_015075 /// XM_006724579 /// XM_006724580 /// XM_006724581 /// XM_006724582 /// XM_006724583 /// XM_006724584 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0030054 // cell junction // not recorded 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 214820_at AJ002572 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ002572.1 /DEF=Homo sapiens mRNA; transcriptional unit N143. /FEA=mRNA /DB_XREF=gi:2959924 /UG=Hs.152108 transcriptional unit N143 AJ002572 bromodomain and WD repeat domain containing 1 BRWD1 54014 NM_001007246 /// NM_018963 /// NM_033656 /// XM_005260994 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214821_at AF052119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052119.1 /DEF=Homo sapiens clone 23622 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360426 /UG=Hs.151608 Homo sapiens clone 23622 mRNA sequence AF052119 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 SLC25A4 291 NM_001151 0000002 // mitochondrial genome maintenance // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015207 // adenine transmembrane transporter activity // traceable author statement 214822_at AF131833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131833.1 /DEF=Homo sapiens clone 24828 mRNA sequence, partial cds. /FEA=mRNA /PROD=Unknown /DB_XREF=gi:4406671 /UG=Hs.21708 hypothetical protein from clone 24828 AF131833 bone morphogenetic protein/retinoic acid inducible neural-specific 2 BRINP2 57795 NM_021165 /// XM_005245379 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 214823_at AF033199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF033199.1 /DEF=Homo sapiens C2H2 zinc finger protein pseudogene, mRNA sequence. /FEA=mRNA /DB_XREF=gi:3252864 /UG=Hs.8198 zinc finger protein 204 AF033199 zinc finger protein 204, pseudogene ZNF204P 7754 NR_002722 /// NR_024553 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214824_at Z73903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z73903.1 /DEF=H.sapiens mRNA for TRPC1A. /FEA=mRNA /PROD=TRPC1A protein /DB_XREF=gi:1359889 /UG=Hs.250687 transient receptor potential channel 1 Z73903 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0046541 // saliva secretion // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0015279 // store-operated calcium channel activity // traceable author statement /// 0044325 // ion channel binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 214825_at L10374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L10374.1 /DEF=Human (clone CTG-A4) mRNA sequence. /FEA=mRNA /DB_XREF=gi:307288 /UG=Hs.281587 Human (clone CTG-A4) mRNA sequence L10374 family with sequence similarity 155, member A FAM155A 728215 NM_001080396 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214826_at U79276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79276.1 /DEF=Human clone 23960 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710244 /UG=Hs.307238 Human clone 23960 mRNA sequence U79276 phosphodiesterase 12 PDE12 201626 NM_177966 0006397 // mRNA processing // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214827_at AL031680 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031680 /DEF=Human DNA sequence from clone 850H21 on chromosome 20q13.11-13.2 Contains a novel gene, a gene for a novel protein containing a PDZ (DHR, GLGF) domain, two putative CpG islands, ESTs, STSs and GSSs /FEA=CDS_1 /DB_XREF=gi:10198605 /UG=Hs.304918 Human DNA sequence from clone 850H21 on chromosome 20q13.11-13.2 Contains a novel gene, a gene for a novel protein containing a PDZ (DHR, GLGF) domain, two putative CpG islands, ESTs, STSs and GSSs AL031680 par-6 family cell polarity regulator beta PARD6B 84612 NM_032521 0006461 // protein complex assembly // inferred from direct assay /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0030334 // regulation of cell migration // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070830 // tight junction assembly // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214828_s_at AL157851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157851.1 /DEF=Novel human gene mapping to chomosome 22. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:7076979 /UG=Hs.301947 kraken-like AL157851 ribosomal RNA processing 7 homolog A (S. cerevisiae) /// ribosomal RNA processing 7 homolog B (S. cerevisiae) RRP7A /// RRP7B 27341 /// 91695 NM_015703 /// NR_002184 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214829_at AK023446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023446.1 /DEF=Homo sapiens cDNA FLJ13384 fis, clone PLACE1001062, highly similar to Homo sapiens mRNA for lysine-ketoglutarate reductasesaccharopine dehydrogenase. /FEA=mRNA /DB_XREF=gi:10435383 /UG=Hs.323091 Homo sapiens cDNA FLJ13384 fis, clone PLACE1001062, highly similar to Homo sapiens mRNA for lysine-ketoglutarate reductasesaccharopine dehydrogenase AK023446 aminoadipate-semialdehyde synthase AASS 10157 NM_005763 /// XR_242220 /// XR_242221 0006554 // lysine catabolic process // non-traceable author statement /// 0006554 // lysine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019477 // L-lysine catabolic process // inferred from electronic annotation /// 0033512 // L-lysine catabolic process to acetyl-CoA via saccharopine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047130 // saccharopine dehydrogenase (NADP+, L-lysine-forming) activity // not recorded /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // not recorded /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // non-traceable author statement 214830_at AI537540 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI537540 /FEA=EST /DB_XREF=gi:4451675 /DB_XREF=est:tp04g11.x1 /CLONE=IMAGE:2186852 /UG=Hs.71168 Homo sapiens clone 24674 mRNA sequence AI537540 solute carrier family 38, member 6 SLC38A6 145389 NM_001172702 /// NM_153811 /// NR_033344 /// XM_006720046 /// XM_006720047 /// XM_006720048 /// XM_006720049 /// XM_006720050 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 214831_at AK024944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024944.1 /DEF=Homo sapiens cDNA: FLJ21291 fis, clone COL01963. /FEA=mRNA /DB_XREF=gi:10437366 /UG=Hs.287657 Homo sapiens cDNA: FLJ21291 fis, clone COL01963 AK024944 ELK4, ETS-domain protein (SRF accessory protein 1) ELK4 2005 NM_001973 /// NM_021795 /// XM_005244950 /// XM_005244951 /// XR_426764 /// XR_426765 /// XR_426766 /// XR_426767 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0070932 // histone H3 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001047 // core promoter binding // traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 214832_at X87870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X87870.1 /DEF=H.sapiens mRNA for hepatocyte nuclear factor 4a. /FEA=mRNA /GEN=HNF4 /PROD=Hepatocyte nuclear factor 4A /DB_XREF=gi:1595751 /UG=Hs.54424 hepatocyte nuclear factor 4, alpha X87870 hepatocyte nuclear factor 4, alpha HNF4A 3172 NM_000457 /// NM_001030003 /// NM_001030004 /// NM_001258355 /// NM_001287182 /// NM_001287183 /// NM_001287184 /// NM_175914 /// NM_178849 /// NM_178850 /// XM_005260407 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006591 // ornithine metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from mutant phenotype /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0060398 // regulation of growth hormone receptor signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214833_at AB007958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007958.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0489. /FEA=mRNA /DB_XREF=gi:3413932 /UG=Hs.169431 KIAA0489 protein AB007958 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 214834_at AU118874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU118874 /FEA=EST /DB_XREF=gi:10934109 /DB_XREF=est:AU118874 /CLONE=HEMBA1004556 /UG=Hs.252085 Homo sapiens PAR5 gene, complete sequence AU118874 Prader Willi/Angelman region RNA 5 PWAR5 8123 NR_022008 214835_s_at AF131748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131748.1 /DEF=Homo sapiens clone 25191 GTP-specific succinyl-CoA synthetase beta subunit (SCS) mRNA sequence, partial cds. /FEA=mRNA /PROD=GTP-specific succinyl-CoA synthetase betasubunit /DB_XREF=gi:4406563 /UG=Hs.247309 succinate-CoA ligase, GDP-forming, beta subunit AF131748 succinate-CoA ligase, GDP-forming, beta subunit SUCLG2 8801 NM_001177599 /// NM_003848 /// XM_005264773 /// XR_245062 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // non-traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045244 // succinate-CoA ligase complex (GDP-forming) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004776 // succinate-CoA ligase (GDP-forming) activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214836_x_at BG536224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG536224 /FEA=EST /DB_XREF=gi:13527769 /DB_XREF=est:602565445F1 /CLONE=IMAGE:4690258 /UG=Hs.123030 Human kappa-immunoglobulin germline pseudogene (Chr22.4) variable region (subgroup V kappa II) BG536224 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214837_at M12523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M12523 /DEF=Human serum albumin (ALB) gene, complete cds /FEA=mRNA_1 /DB_XREF=gi:178343 /UG=Hs.184411 albumin M12523 albumin ALB 213 NM_000477 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008206 // bile acid metabolic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0019836 // hemolysis by symbiont of host erythrocytes // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // non-traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0051659 // maintenance of mitochondrion location // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070541 // response to platinum ion // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005504 // fatty acid binding // non-traceable author statement /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015643 // toxic substance binding // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0019825 // oxygen binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 214838_at AL035297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035297.1 /DEF=H.sapiens gene from PAC 747L4. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4200248 /UG=Hs.119254 H.sapiens gene from PAC 747L4 AL035297 SFT2 domain containing 2 SFT2D2 375035 NM_199344 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 214839_at AF052108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052108.1 /DEF=Homo sapiens clone 23687 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360415 /UG=Hs.12513 Homo sapiens clone 23687 mRNA sequence AF052108 long intergenic non-protein coding RNA 599 /// microRNA 124-1 LINC00599 /// MIR124-1 157627 /// 406907 NR_024281 /// NR_029668 214840_at AF038192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF038192.1 /DEF=Homo sapiens clone 23808 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2795912 /UG=Hs.12537 Homo sapiens clone 23808 mRNA sequence AF038192 target of myb1-like 2 (chicken) TOM1L2 146691 NM_001033551 /// NM_001082968 /// NM_001288786 /// NM_001288787 /// NM_001288788 /// NM_001288789 /// NM_144678 /// XM_005256461 /// XM_005256462 /// XM_005256463 /// XM_005256466 /// XM_006721452 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from direct assay 214841_at AF070524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070524.1 /DEF=Homo sapiens clone 24453 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387879 /UG=Hs.13410 Homo sapiens clone 24453 mRNA sequence AF070524 cornichon family AMPA receptor auxiliary protein 3 CNIH3 149111 NM_152495 /// XM_005273075 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0016247 // channel regulator activity // inferred from electronic annotation 214842_s_at M12523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M12523 /DEF=Human serum albumin (ALB) gene, complete cds /FEA=mRNA_1 /DB_XREF=gi:178343 /UG=Hs.184411 albumin M12523 albumin ALB 213 NM_000477 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008206 // bile acid metabolic process // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0019836 // hemolysis by symbiont of host erythrocytes // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // non-traceable author statement /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046010 // positive regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0046689 // response to mercury ion // inferred from electronic annotation /// 0051659 // maintenance of mitochondrion location // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070541 // response to platinum ion // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005504 // fatty acid binding // non-traceable author statement /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015643 // toxic substance binding // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0019825 // oxygen binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 214843_s_at AK022864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022864.1 /DEF=Homo sapiens cDNA FLJ12802 fis, clone NT2RP2002124, weakly similar to UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (EC 3.1.2.15). /FEA=mRNA /DB_XREF=gi:10434503 /UG=Hs.173694 KIAA1097 protein AK022864 ubiquitin specific peptidase 33 USP33 23032 NM_015017 /// NM_201624 /// NM_201626 /// XM_005270648 /// XM_005270649 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from mutant phenotype /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030891 // VCB complex // traceable author statement /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214844_s_at AL050069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050069.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566A0946 (from clone DKFZp566A0946); partial cds. /FEA=mRNA /GEN=DKFZp566A0946 /PROD=hypothetical protein /DB_XREF=gi:4884299 /UG=Hs.78006 DKFZP566A0946 protein AL050069 docking protein 5 DOK5 55816 NM_001294161 /// NM_018431 /// NM_177959 /// XM_005260451 0000165 // MAPK cascade // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 214845_s_at AF257659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF257659.1 /DEF=Homo sapiens crocalbin-like protein mRNA, partial cds. /FEA=mRNA /PROD=crocalbin-like protein /DB_XREF=gi:8515717 /UG=Hs.302073 Homo sapiens crocalbin-like protein mRNA, partial cds AF257659 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 214846_s_at AB037751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037751.1 /DEF=Homo sapiens mRNA for KIAA1330 protein, partial cds. /FEA=mRNA /GEN=KIAA1330 /PROD=KIAA1330 protein /DB_XREF=gi:7243040 /UG=Hs.301242 KIAA1330 protein AB037751 alpha-kinase 3 ALPK3 57538 NM_020778 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 214847_s_at BG111168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG111168 /FEA=EST /DB_XREF=gi:12604674 /DB_XREF=est:602281582F1 /CLONE=IMAGE:4369100 /UG=Hs.288316 chromosome 6 open reading frame 9 BG111168 G-protein signaling modulator 3 GPSM3 63940 NM_001276501 /// NM_022107 0006955 // immune response // non-traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from electronic annotation 214848_at U79277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79277.1 /DEF=Human clone 23548 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710245 /UG=Hs.71848 Human clone 23548 mRNA sequence U79277 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214849_at AW500220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW500220 /FEA=EST /DB_XREF=gi:7112628 /DB_XREF=est:UI-HF-BN0-akd-c-02-0-UI.r1 /CLONE=IMAGE:3076610 /UG=Hs.332496 Human DNA sequence from clone 108K11 on chromosome 6p21 Contains SRP20 (SR protein family member), Ndr protein kinase gene similar to yeast suppressor protein SRP40, EST and GSS AW500220 potassium channel tetramerization domain containing 20 KCTD20 222658 NM_001286579 /// NM_001286580 /// NM_173562 /// NR_104480 /// NR_104481 /// XM_005248940 /// XM_006715023 /// XM_006715024 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214850_at X75940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X75940.1 /DEF=H.sapiens beta glucuronidase pseudogene. /FEA=mRNA /DB_XREF=gi:1052700 /UG=Hs.324728 SMA5 X75940 glucuronidase, beta pseudogene SMA4 11039 NM_006780 /// NM_021652 /// NR_024054 /// NR_029426 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 214851_at X87870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X87870.1 /DEF=H.sapiens mRNA for hepatocyte nuclear factor 4a. /FEA=mRNA /GEN=HNF4 /PROD=Hepatocyte nuclear factor 4A /DB_XREF=gi:1595751 /UG=Hs.54424 hepatocyte nuclear factor 4, alpha X87870 hepatocyte nuclear factor 4, alpha HNF4A 3172 NM_000457 /// NM_001030003 /// NM_001030004 /// NM_001258355 /// NM_001287182 /// NM_001287183 /// NM_001287184 /// NM_175914 /// NM_178849 /// NM_178850 /// XM_005260407 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006591 // ornithine metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from mutant phenotype /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0060398 // regulation of growth hormone receptor signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214852_x_at BF573874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF573874 /FEA=EST /DB_XREF=gi:11647586 /DB_XREF=est:602132081F1 /CLONE=IMAGE:4271156 /UG=Hs.53542 KIAA0986 protein BF573874 vacuolar protein sorting 13 homolog A (S. cerevisiae) VPS13A 23230 NM_001018037 /// NM_001018038 /// NM_015186 /// NM_033305 /// XR_242579 /// XR_242580 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008104 // protein localization // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0031045 // dense core granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214853_s_at AI091079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI091079 /FEA=EST /DB_XREF=gi:3430138 /DB_XREF=est:qa53e05.s1 /CLONE=IMAGE:1690496 /UG=Hs.81972 SHC (Src homology 2 domain-containing) transforming protein 1 AI091079 SHC (Src homology 2 domain containing) transforming protein 1 SHC1 6464 NM_001130040 /// NM_001130041 /// NM_001202859 /// NM_003029 /// NM_183001 /// XM_005245449 /// XM_005245450 /// XM_005245451 /// XM_005245452 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 214854_at AC004490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004490 /DEF=Homo sapiens chromosome 19, cosmid R29381 /FEA=CDS /DB_XREF=gi:2995576 /UG=Hs.156015 Homo sapiens chromosome 19, cosmid R29381 AC004490 /// Homo sapiens cDNA FLJ33701 fis, clone BRAWH2005524. AC004490.1 /// AX746733 214855_s_at AL050050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050050.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566D133 (from clone DKFZp566D133); partial cds. /FEA=mRNA /GEN=DKFZp566D133 /PROD=hypothetical protein /DB_XREF=gi:4884287 /UG=Hs.167031 DKFZP566D133 protein AL050050 Ral GTPase activating protein, alpha subunit 1 (catalytic) /// Ral GTPase activating protein, alpha subunit 1 (catalytic) pseudogene RALGAPA1 /// RALGAPA1P 26134 /// 253959 NM_001283043 /// NM_001283044 /// NM_014990 /// NM_194301 /// NR_104269 /// XM_005267491 /// XM_005267492 /// XM_005267493 /// XM_005267498 /// XM_006720098 /// XM_006720099 /// XM_006720100 /// XM_006720101 /// XM_006720102 /// XM_006720103 /// XM_006720104 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // not recorded /// 0032859 // activation of Ral GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // /// 0005488 // binding // inferred from electronic annotation /// 0017123 // Ral GTPase activator activity // not recorded /// 0017123 // Ral GTPase activator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction 214856_at BF434424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF434424 /FEA=EST /DB_XREF=gi:11446712 /DB_XREF=est:7o96h09.x1 /CLONE=IMAGE:3644393 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 BF434424 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214857_at AL050035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050035.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566H0124 (from clone DKFZp566H0124). /FEA=mRNA /DB_XREF=gi:4884276 /UG=Hs.133130 Homo sapiens mRNA; cDNA DKFZp566H0124 (from clone DKFZp566H0124) AL050035 RPARP antisense RNA 1 RPARP-AS1 100505761 NR_038937 /// NR_038938 214858_at AF070536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070536.1 /DEF=Homo sapiens clone 24566 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387893 /UG=Hs.133342 Homo sapiens clone 24566 mRNA sequence AF070536 uncharacterized LOC100130449 PP14571 100130449 NR_024014 214859_at AI635302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI635302 /FEA=EST /DB_XREF=gi:4686632 /DB_XREF=est:tz80d11.x1 /CLONE=IMAGE:2294901 /UG=Hs.123420 KIAA1061 protein AI635302 follistatin-like 4 FSTL4 23105 NM_015082 0005576 // extracellular region // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214860_at AL022165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022165 /DEF=Human DNA sequence from clone 71L16 on chromosome Xp11. Contains a probable Zinc Finger protein (pseudo)gene, an unknown putative gene, a pseudogene with high similarity to part of antigen KI-67, a putative Chondroitin 6-Sulfotransferase LIKE gene... /FEA=mRNA_2 /DB_XREF=gi:3281985 /UG=Hs.154353 Human DNA sequence from clone 71L16 on chromosome Xp11. Contains a probable Zinc Finger protein (pseudo)gene, an unknown putative gene, a pseudogene with high similarity to part of antigen KI-67, a putative Chondroitin 6-Sulfotransferase LIKE gene and a K AL022165 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 SLC9A7 84679 NM_001257291 /// NM_032591 /// XM_005272680 /// XM_005272681 /// XM_005272682 /// XM_005272684 /// XM_006724564 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from direct assay /// 0015386 // potassium:proton antiporter activity // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement 214861_at AI341811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI341811 /FEA=EST /DB_XREF=gi:4078738 /DB_XREF=est:qt04f03.x1 /CLONE=IMAGE:1946621 /UG=Hs.149918 gene amplified in squamous cell carcinoma 1; KIAA0780 protein AI341811 lysine (K)-specific demethylase 4C KDM4C 23081 NM_001146694 /// NM_001146695 /// NM_001146696 /// NM_015061 /// XM_006716741 /// XR_428422 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0033169 // histone H3-K9 demethylation // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051213 // dioxygenase activity // inferred from electronic annotation 214862_x_at AL080082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080082.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G1162 (from clone DKFZp564G1162). /FEA=mRNA /DB_XREF=gi:5262495 /UG=Hs.139006 Homo sapiens mRNA; cDNA DKFZp564G1162 (from clone DKFZp564G1162) AL080082 RP11-119F7.5 214863_at AL022165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022165 /DEF=Human DNA sequence from clone 71L16 on chromosome Xp11. Contains a probable Zinc Finger protein (pseudo)gene, an unknown putative gene, a pseudogene with high similarity to part of antigen KI-67, a putative Chondroitin 6-Sulfotransferase LIKE gene... /FEA=mRNA_2 /DB_XREF=gi:3281985 /UG=Hs.154353 Human DNA sequence from clone 71L16 on chromosome Xp11. Contains a probable Zinc Finger protein (pseudo)gene, an unknown putative gene, a pseudogene with high similarity to part of antigen KI-67, a putative Chondroitin 6-Sulfotransferase LIKE gene and a K AL022165 214864_s_at AK024386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024386.1 /DEF=Homo sapiens cDNA FLJ14324 fis, clone PLACE4000100, highly similar to Homo sapiens hydroxypyruvate reductase (GRHPR) gene. /FEA=mRNA /DB_XREF=gi:10436760 /UG=Hs.155742 glyoxylate reductasehydroxypyruvate reductase AK024386 glyoxylate reductase/hydroxypyruvate reductase GRHPR 9380 NM_012203 /// XM_005251631 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007588 // excretion // inferred from mutant phenotype /// 0008152 // metabolic process // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043648 // dicarboxylic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0008465 // glycerate dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016618 // hydroxypyruvate reductase activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay 214865_at AC004490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004490 /DEF=Homo sapiens chromosome 19, cosmid R29381 /FEA=CDS /DB_XREF=gi:2995576 /UG=Hs.156015 Homo sapiens chromosome 19, cosmid R29381 AC004490 DOT1-like histone H3K79 methyltransferase DOT1L 84444 NM_032482 /// XM_005259659 /// XM_005259660 /// XM_006722923 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // inferred from direct assay /// 2000677 // regulation of transcription regulatory region DNA binding // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from electronic annotation 214866_at X74039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X74039.1 /DEF=H.sapiens mRNA for urokinase plasminogen activator receptor. /FEA=mRNA /PROD=urokinase plasminogen activator receptor /DB_XREF=gi:456192 /UG=Hs.179657 plasminogen activator, urokinase receptor X74039 plasminogen activator, urokinase receptor PLAUR 5329 NM_001005376 /// NM_001005377 /// NM_002659 /// XM_005258988 /// XM_005258989 /// XM_005258990 /// XM_006723241 0006501 // C-terminal protein lipidation // traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030162 // regulation of proteolysis // non-traceable author statement /// 0038195 // urokinase plasminogen activator signaling pathway // non-traceable author statement /// 0042730 // fibrinolysis // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030377 // urokinase plasminogen activator receptor activity // non-traceable author statement 214867_at AL080182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080182.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O151 (from clone DKFZp434O151). /FEA=mRNA /DB_XREF=gi:5262658 /UG=Hs.225129 Homo sapiens mRNA; cDNA DKFZp434O151 (from clone DKFZp434O151) AL080182 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 /// ZSWIM8 antisense RNA 1 NDST2 /// ZSWIM8-AS1 8509 /// 100507331 NM_003635 /// NR_038357 /// XM_005270255 /// XM_005270256 /// XM_006718046 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214868_at AW189518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW189518 /FEA=EST /DB_XREF=gi:6463982 /DB_XREF=est:xl07g10.x1 /CLONE=IMAGE:2675586 /UG=Hs.194712 piwi (Drosophila)-like 1 AW189518 piwi-like RNA-mediated gene silencing 1 PIWIL1 9271 NM_001190971 /// NM_004764 /// XM_005253632 /// XM_006719698 0006417 // regulation of translation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005844 // polysome // inferred from electronic annotation /// 0005845 // mRNA cap binding complex // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0043186 // P granule // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0034584 // piRNA binding // inferred from sequence or structural similarity 214869_x_at AK021533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021533.1 /DEF=Homo sapiens cDNA FLJ11471 fis, clone HEMBA1001675, weakly similar to VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS9. /FEA=mRNA /DB_XREF=gi:10432733 /UG=Hs.306601 Homo sapiens cDNA FLJ11471 fis, clone HEMBA1001675, weakly similar to VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS9 AK021533 GTPase activating protein and VPS9 domains 1 GAPVD1 26130 NM_001282679 /// NM_001282680 /// NM_001282681 /// NM_015635 /// XM_005251901 /// XM_005251904 /// XM_006717042 /// XM_006717043 /// XM_006717044 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051223 // regulation of protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from mutant phenotype 214870_x_at AC002045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002045 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-589H1 /FEA=mRNA_2 /DB_XREF=gi:2951945 /UG=Hs.251928 nuclear pore complex interacting protein AC002045 polycystin-1-like /// nuclear pore complex-interacting protein family member A1-like /// nuclear pore complex interacting protein family, member A1 /// nuclear pore complex interacting protein family, member A2 /// nuclear pore complex interacting protein family, member A3 /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member A7 /// nuclear pore complex interacting protein family, member A8 /// polycystic kidney disease 1 (autosomal dominant) pseudogene 1 LOC101930075 /// LOC102724993 /// NPIPA1 /// NPIPA2 /// NPIPA3 /// NPIPA5 /// NPIPA7 /// NPIPA8 /// PKD1P1 9284 /// 339044 /// 642778 /// 642799 /// 100288332 /// 101059938 /// 101059953 /// 101930075 /// 102724993 NM_001277323 /// NM_001277324 /// NM_001277325 /// NM_001282507 /// NM_001282511 /// NM_006985 /// NR_036447 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005255484 /// XM_005255485 /// XM_005255486 /// XM_005255487 /// XM_005255488 /// XM_005255489 /// XM_005255490 /// XM_005255491 /// XM_005255492 /// XM_005255694 /// XM_005255695 /// XM_005255735 /// XM_005255737 /// XM_005255738 /// XM_005276493 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006720829 /// XM_006720830 /// XM_006720916 /// XM_006720917 /// XM_006720979 /// XM_006720980 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006725190 /// XM_006725191 /// XM_006725205 /// XM_006725206 /// XM_006725207 /// XM_006725208 /// XM_006725209 /// XM_006725210 /// XM_006725211 /// XM_006725212 /// XM_006725213 /// XM_006725232 /// XM_006725233 /// XM_006725234 /// XM_006725235 /// XM_006726604 /// XM_006726605 /// XM_006726606 /// XM_006726607 0006810 // transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 214871_x_at BC005066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005066.1 /DEF=Homo sapiens, clone IMAGE:3347954, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3347954) /DB_XREF=gi:13477204 /UG=Hs.233354 Homo sapiens, clone IMAGE:3347954, mRNA, partial cds BC005066 uncharacterized LOC100287590 LOC100287590 100287590 XM_002343551 214872_at AL080129 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080129.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D193 (from clone DKFZp434D193); partial cds. /FEA=mRNA /GEN=DKFZp434D193 /PROD=hypothetical protein /DB_XREF=gi:5262567 /UG=Hs.225841 DKFZP434D193 protein AL080129 uncharacterized LOC101929336 /// replication timing regulatory factor 1 LOC101929336 /// RIF1 55183 /// 101929336 NM_001177663 /// NM_001177664 /// NM_001177665 /// NM_018151 /// XM_005246665 /// XM_006712609 /// XM_006712610 /// XM_006712611 /// XR_241332 /// XR_251199 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 214873_at AL137651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137651.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O0213 (from clone DKFZp434O0213); partial cds. /FEA=mRNA /GEN=DKFZp434O0213 /PROD=hypothetical protein /DB_XREF=gi:6807717 /UG=Hs.272317 Homo sapiens mRNA; cDNA DKFZp434O0213 (from clone DKFZp434O0213); partial cds AL137651 low density lipoprotein receptor-related protein 5-like LRP5L 91355 NM_001135772 /// NM_182492 /// XM_006724372 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // not recorded /// 0060070 // canonical Wnt signaling pathway // not recorded 0017147 // Wnt-protein binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 214874_at AL050364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050364.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G052 (from clone DKFZp564G052). /FEA=mRNA /DB_XREF=gi:4914598 /UG=Hs.302761 Homo sapiens mRNA; cDNA DKFZp564G052 (from clone DKFZp564G052) AL050364 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214875_x_at AW001847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW001847 /FEA=EST /DB_XREF=gi:5848763 /DB_XREF=est:wt81a04.x1 /CLONE=IMAGE:2513838 /UG=Hs.279518 amyloid beta (A4) precursor-like protein 2 AW001847 amyloid beta (A4) precursor-like protein 2 APLP2 334 NM_001142276 /// NM_001142277 /// NM_001142278 /// NM_001243299 /// NM_001642 /// NR_024515 /// NR_024516 0001967 // suckling behavior // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046914 // transition metal ion binding // inferred from electronic annotation 214876_s_at AI628925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI628925 /FEA=EST /DB_XREF=gi:4665725 /DB_XREF=est:ty40c08.x1 /CLONE=IMAGE:2281550 /UG=Hs.31476 Homo sapiens cDNA FLJ13872 fis, clone THYRO1001322 AI628925 tubulin, gamma complex associated protein 5 TUBGCP5 114791 NM_001102610 /// NM_052903 /// XM_005272540 /// XM_006725174 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // inferred from direct assay 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // inferred from direct assay 0008017 // microtubule binding // inferred from direct assay 214877_at BE794663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE794663 /FEA=EST /DB_XREF=gi:10215861 /DB_XREF=est:601590459F1 /CLONE=IMAGE:3944463 /UG=Hs.306668 Homo sapiens cDNA FLJ14089 fis, clone MAMMA1000257 BE794663 CDK5 regulatory subunit associated protein 1-like 1 CDKAL1 54901 NM_017774 /// XM_006715127 /// XM_006715128 0008033 // tRNA processing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0035600 // tRNA methylthiolation // inferred from electronic annotation /// 0043412 // macromolecule modification // inferred from electronic annotation /// 1990145 // maintenance of translational fidelity // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035598 // N6-threonylcarbomyladenosine methylthiotransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 214878_at AU118165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU118165 /FEA=EST /DB_XREF=gi:10933190 /DB_XREF=est:AU118165 /CLONE=HEMBA1003008 /UG=Hs.54488 zinc finger protein 37a (KOX 21) AU118165 zinc finger protein 761-like /// zinc finger protein 37A LOC101929740 /// ZNF37A 7587 /// 101929740 NM_001007094 /// NM_001178101 /// NM_003421 /// XM_005252581 /// XM_005252582 /// XM_005252583 /// XM_005252585 /// XM_005252586 /// XM_005252654 /// XM_006717501 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214879_x_at AY007087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AY007087.1 /DEF=Homo sapiens clone TCCCIA00046 mRNA sequence. /FEA=mRNA /DB_XREF=gi:9955976 /UG=Hs.93649 upstream transcription factor 2, c-fos interacting AY007087 upstream transcription factor 2, c-fos interacting USF2 7392 NM_003367 /// NM_207291 /// XM_005259197 0000430 // regulation of transcription from RNA polymerase II promoter by glucose // inferred by curator /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from mutant phenotype /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007595 // lactation // inferred from electronic annotation /// 0019086 // late viral transcription // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 214880_x_at D90453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D90453.1 /DEF=Human mRNA for l-caldesmon II. /FEA=mRNA /DB_XREF=gi:219897 /UG=Hs.325474 caldesmon 1 D90453 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 214881_s_at X56687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X56687.1 /DEF=H.sapiens mRNA for autoantigen NOR-90. /FEA=mRNA /PROD=autoantigen NOR-90 /DB_XREF=gi:28970 /UG=Hs.89781 upstream binding transcription factor, RNA polymerase I X56687 upstream binding transcription factor, RNA polymerase I UBTF 7343 NM_001076683 /// NM_001076684 /// NM_014233 /// NR_045058 /// XM_006722059 /// XM_006722060 /// XM_006722061 0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214882_s_at BG254869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG254869 /FEA=EST /DB_XREF=gi:12764685 /DB_XREF=est:602369310F1 /CLONE=IMAGE:4477371 /UG=Hs.73965 splicing factor, arginineserine-rich 2 BG254869 microRNA 636 /// serine/arginine-rich splicing factor 2 MIR636 /// SRSF2 6427 /// 693221 NM_001195427 /// NM_003016 /// NR_030366 /// NR_036608 /// XR_429913 /// XR_429914 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214883_at X55005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X55005.1 /DEF=Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene). /FEA=mRNA /GEN=c-erbA-1 /PROD=thyriod hormone receptor alpha 1, THRA1 /DB_XREF=gi:29878 /UG=Hs.724 thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog) X55005 thyroid hormone receptor, alpha THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 214884_at AL033403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL033403 /DEF=Human DNA sequence from clone 88D7 on chromosome Xq25-26.3 Contains F9 (coagulation factor IX (plasma thromboplastic component, Christmas disease, haemophilia B)), dbl oncogene. EST, STS, GSS /FEA=mRNA_1 /DB_XREF=gi:3859054 /UG=Hs.89543 MCF.2 cell line derived transforming sequence AL033403 MCF.2 cell line derived transforming sequence MCF2 4168 NM_001099855 /// NM_001171876 /// NM_001171877 /// NM_001171878 /// NM_001171879 /// NM_005369 /// XM_005262413 /// XM_005262414 /// XM_006724757 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 214885_at AL050395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050395.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D1020 (from clone DKFZp586D1020). /FEA=mRNA /DB_XREF=gi:4914616 /UG=Hs.42343 member of MYST family histone acetyl transferases, homolog of Drosophila MOF AL050395 K(lysine) acetyltransferase 8 KAT8 84148 NM_032188 /// NM_182958 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay /// 0072487 // MSL complex // inferred from direct assay 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 214886_s_at AL049786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049786.1 /DEF=Novel human gene mapping to chomosome 13. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4902708 /UG=Hs.22174 Novel human gene mapping to chomosome 13 AL049786 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 214887_at AL049786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049786.1 /DEF=Novel human gene mapping to chomosome 13. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4902708 /UG=Hs.22174 Novel human gene mapping to chomosome 13 AL049786 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 214888_at AK023851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023851.1 /DEF=Homo sapiens cDNA FLJ13789 fis, clone SKNMC1000050, moderately similar to CALPAIN 2, LARGE CATALYTIC SUBUNIT (EC 3.4.22.17). /FEA=mRNA /DB_XREF=gi:10435914 /UG=Hs.76288 calpain 2, (mII) large subunit AK023851 calpain 2, (m/II) large subunit CAPN2 824 NM_001146068 /// NM_001748 0001666 // response to hypoxia // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred by curator /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // traceable author statement /// 0031143 // pseudopodium // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214889_at AL080065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080065.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J102 (from clone DKFZp564J102); partial cds. /FEA=mRNA /GEN=DKFZp564J102 /PROD=hypothetical protein /DB_XREF=gi:5262471 /UG=Hs.101735 DKFZP564J102 protein AL080065 family with sequence similarity 149, member A FAM149A 25854 NM_001006655 /// NM_015398 /// XM_005262901 /// XM_005262902 /// XM_005262903 /// XM_005262904 /// XM_005262905 /// XM_005262906 /// XM_005262907 /// XM_005262908 /// XM_005262909 /// XM_005262910 /// XM_005262911 /// XM_005262912 /// XM_005262913 214890_s_at AL080065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080065.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J102 (from clone DKFZp564J102); partial cds. /FEA=mRNA /GEN=DKFZp564J102 /PROD=hypothetical protein /DB_XREF=gi:5262471 /UG=Hs.101735 DKFZP564J102 protein AL080065 family with sequence similarity 149, member A FAM149A 25854 NM_001006655 /// NM_015398 /// XM_005262901 /// XM_005262902 /// XM_005262903 /// XM_005262904 /// XM_005262905 /// XM_005262906 /// XM_005262907 /// XM_005262908 /// XM_005262909 /// XM_005262910 /// XM_005262911 /// XM_005262912 /// XM_005262913 214891_at U79257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79257.1 /DEF=Human clone 23932 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710210 /UG=Hs.197766 Human clone 23932 mRNA sequence U79257 F-box protein 21 FBXO21 23014 NM_015002 /// NM_033624 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 214892_x_at BC004262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004262.1 /DEF=Homo sapiens, Similar to cactin, clone IMAGE:3609158, mRNA, partial cds. /FEA=mRNA /PROD=Similar to cactin /DB_XREF=gi:13279055 /UG=Hs.128425 NY-REN-24 antigen BC004262 cactin, spliceosome C complex subunit CACTIN 58509 NM_001080543 /// NM_021231 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214893_x_at AI421964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI421964 /FEA=EST /DB_XREF=gi:4267895 /DB_XREF=est:tf40a10.x1 /CLONE=IMAGE:2098650 /UG=Hs.124161 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 AI421964 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 HCN2 610 NM_001194 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // not recorded /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // inferred from mutant phenotype /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // inferred from mutant phenotype /// 0005261 // cation channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 214894_x_at AK023285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023285.1 /DEF=Homo sapiens cDNA FLJ13223 fis, clone OVARC1000001, highly similar to Homo sapiens mRNA for actin binding protein ABP620. /FEA=mRNA /DB_XREF=gi:10435154 /UG=Hs.108258 actin binding protein; macrophin (microfilament and actin filament cross-linker protein) AK023285 microtubule-actin crosslinking factor 1 MACF1 23499 NM_012090 /// NM_033044 /// XM_005270694 /// XM_005270695 /// XM_005270696 /// XM_005270697 /// XM_005270698 /// XM_005270700 /// XM_006710519 /// XM_006710520 /// XM_006710521 /// XM_006710522 /// XM_006710523 /// XM_006710524 /// XM_006710525 /// XM_006710526 /// XM_006710527 /// XM_006710528 /// XM_006710529 /// XM_006710530 /// XM_006710531 /// XM_006710532 /// XM_006710533 /// XM_006710534 /// XM_006710535 /// XM_006710536 /// XM_006710537 /// XM_006710538 /// XM_006710539 /// XM_006710540 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010632 // regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // non-traceable author statement 214895_s_at AU135154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU135154 /FEA=EST /DB_XREF=gi:10995693 /DB_XREF=est:AU135154 /CLONE=PLACE1001348 /UG=Hs.172028 a disintegrin and metalloproteinase domain 10 AU135154 ADAM metallopeptidase domain 10 ADAM10 102 NM_001110 /// XM_005254117 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051089 // constitutive protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay /// 0097197 // tetraspanin-enriched microdomain // inferred from direct assay 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005102 // receptor binding // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 214896_at AL109671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109671.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 29222. /FEA=mRNA /DB_XREF=gi:5689802 /UG=Hs.140833 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 29222 AL109671 long intergenic non-protein coding RNA 1314 LINC01314 100996492 NR_120317 /// XR_243192 /// XR_248146 /// XR_253417 /// XR_424651 /// XR_429574 /// XR_433141 214897_at AB007975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007975.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0506. /FEA=mRNA /DB_XREF=gi:3413950 /UG=Hs.131454 KIAA0506 protein AB007975 214898_x_at AB038783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB038783.1 /DEF=Homo sapiens MUC3B mRNA for intestinal mucin, partial cds. /FEA=mRNA /GEN=MUC3B /PROD=intestinal mucin /DB_XREF=gi:9929917 /UG=Hs.129782 mucin 3A, intestinal AB038783 mucin 3B, cell surface associated MUC3B 57876 XM_005276299 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 214899_at AC007842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007842 /DEF=Homo sapiens chromosome 19, BAC 331191 (CIT-B-471f3) /FEA=CDS_2 /DB_XREF=gi:5080755 /UG=Hs.154390 Homo sapiens chromosome 19, BAC 331191 (CIT-B-471f3) AC007842 zinc finger protein 780B ZNF780B 163131 NM_001005851 /// XM_005258590 /// XM_005258591 /// XM_005258592 /// XM_005258593 /// XM_005258595 /// XM_006723072 /// XM_006723073 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 214900_at AC004522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004522 /DEF=Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 /FEA=CDS_3 /DB_XREF=gi:3006227 /UG=Hs.154212 Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 AC004522 zinc finger with KRAB and SCAN domains 1 ZKSCAN1 7586 NM_001287054 /// NM_001287055 /// NM_003439 /// XM_005250565 /// XM_006716112 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214901_at AI671579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI671579 /FEA=EST /DB_XREF=gi:4851310 /DB_XREF=est:wb33h07.x1 /CLONE=IMAGE:2307517 /UG=Hs.2077 zinc finger protein 8 (clone HF.18) AI671579 zinc finger protein 8 ZNF8 7554 NM_021089 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 214902_x_at AL080232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080232.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586A061 (from clone DKFZp586A061). /FEA=mRNA /DB_XREF=gi:5262725 /UG=Hs.220696 Homo sapiens mRNA; cDNA DKFZp586A061 (from clone DKFZp586A061) AL080232 LIM domain containing preferred translocation partner in lipoma LPP 4026 NM_001167671 /// NM_001167672 /// NM_005578 /// XM_005247444 /// XM_005247445 /// XM_005247446 /// XM_005247447 /// XM_005247448 /// XM_005247450 /// XM_005247451 /// XM_005247453 /// XM_006713637 0007155 // cell adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214903_at AF070580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070580.1 /DEF=Homo sapiens clone 24527 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387952 /UG=Hs.25422 Homo sapiens clone 24527 mRNA sequence AF070580 synaptotagmin II SYT2 127833 NM_001136504 /// NM_177402 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214904_at AI927984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI927984 /FEA=EST /DB_XREF=gi:5663948 /DB_XREF=est:wo92c02.x1 /CLONE=IMAGE:2462786 /UG=Hs.227767 zinc finger protein 41 AI927984 zinc finger protein 41 ZNF41 7592 NM_007130 /// NM_153380 /// XM_005272665 /// XM_005272666 /// XM_005272668 /// XM_005272669 /// XM_006724550 /// XM_006724551 /// XM_006724552 /// XM_006724553 /// XM_006724554 /// XM_006724555 /// XM_006724556 /// XM_006724557 /// XM_006724558 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 214905_at AL109674 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109674.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 46866. /FEA=mRNA /DB_XREF=gi:5689832 /UG=Hs.221811 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 46866 AL109674 Ras protein-specific guanine nucleotide-releasing factor 1 RASGRF1 5923 NM_001145648 /// NM_002891 /// NM_153815 /// XM_005254578 /// XM_006720627 /// XM_006720628 /// XM_006720629 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007616 // long-term memory // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0043005 // neuron projection // non-traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation 214906_x_at AL049786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049786.1 /DEF=Novel human gene mapping to chomosome 13. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4902708 /UG=Hs.22174 Novel human gene mapping to chomosome 13 AL049786 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 214907_at BF110434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110434 /FEA=EST /DB_XREF=gi:10940124 /DB_XREF=est:7n52h07.x1 /CLONE=IMAGE:3568380 /UG=Hs.230424 Homo sapiens cDNA FLJ13540 fis, clone PLACE1006754, weakly similar to BILIARY GLYCOPROTEIN 1 PRECURSOR BF110434 carcinoembryonic antigen-related cell adhesion molecule 21 CEACAM21 90273 NM_001098506 /// NM_001288773 /// NM_001290113 /// NM_033543 /// NR_110107 /// XM_005278396 /// XM_005278397 /// XM_006725394 /// XM_006725395 /// XM_006725396 /// XR_424988 /// XR_430247 /// XR_430808 /// XR_433578 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214908_s_at AC004893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004893 /DEF=Homo sapiens PAC clone RP4-808A1 from 7q21.1-q31.1 /FEA=CDS_1 /DB_XREF=gi:3694662 /UG=Hs.247755 Homo sapiens PAC clone RP4-808A1 from 7q21.1-q31.1 AC004893 transformation/transcription domain-associated protein TRRAP 8295 NM_001244580 /// NM_003496 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // non-traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0000125 // PCAF complex // non-traceable author statement /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 214909_s_at AK026191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026191.1 /DEF=Homo sapiens cDNA: FLJ22538 fis, clone HRC13212, highly similar to AF070667 Homo sapiens NG,NG-dimethylarginine dimethylaminohydrolase homolog mRNA. /FEA=mRNA /DB_XREF=gi:10438961 /UG=Hs.247362 dimethylarginine dimethylaminohydrolase 2 AK026191 dimethylarginine dimethylaminohydrolase 2 DDAH2 23564 NM_013974 /// XM_005248974 /// XM_005272783 /// XM_005274929 /// XM_005275086 /// XM_005275225 /// XM_005275361 /// XM_005275522 0000052 // citrulline metabolic process // inferred from direct assay /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016403 // dimethylargininase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation 214910_s_at AF161454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161454.1 /DEF=Homo sapiens HSPC336 mRNA, partial cds. /FEA=mRNA /PROD=HSPC336 /DB_XREF=gi:6841321 /UG=Hs.247129 apolipoprotein M AF161454 apolipoprotein M APOM 55937 NM_001256169 /// NM_019101 /// NR_045828 /// XM_006715150 /// XM_006725493 /// XM_006725707 /// XM_006725824 /// XM_006725916 /// XM_006726009 /// XM_006726104 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034445 // negative regulation of plasma lipoprotein particle oxidation // inferred from direct assay /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred by curator /// 0043691 // reverse cholesterol transport // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034365 // discoidal high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005319 // lipid transporter activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay 214911_s_at S78771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S78771.1 /DEF=NAT=CpG island-associated gene human, mRNA, 1741 nt. /FEA=mRNA /DB_XREF=gi:244232 /UG=Hs.75243 bromodomain-containing 2 S78771 bromodomain containing 2 BRD2 6046 NM_001113182 /// NM_001199455 /// NM_001199456 /// NM_001291986 /// NM_005104 /// NR_037625 /// XR_241911 /// XR_246967 /// XR_247375 /// XR_247406 /// XR_247427 0006334 // nucleosome assembly // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 214912_at AK022067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022067.1 /DEF=Homo sapiens cDNA FLJ12005 fis, clone HEMBB1001565. /FEA=mRNA /DB_XREF=gi:10433387 /UG=Hs.287477 Homo sapiens cDNA FLJ12005 fis, clone HEMBB1001565 AK022067 214913_at AB002364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002364.1 /DEF=Human mRNA for KIAA0366 gene, partial cds. /FEA=mRNA /GEN=KIAA0366 /DB_XREF=gi:2224672 /UG=Hs.27916 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 AB002364 ADAM metallopeptidase with thrombospondin type 1 motif, 3 ADAMTS3 9508 NM_014243 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0010573 // vascular endothelial growth factor production // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred by curator /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // non-traceable author statement /// 0032964 // collagen biosynthetic process // inferred from direct assay /// 0043206 // extracellular fibril organization // inferred by curator /// 1900748 // positive regulation of vascular endothelial growth factor signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214914_at U79304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79304.1 /DEF=Human clone 23909 mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1710291 /UG=Hs.281043 Human clone 23909 mRNA, partial cds U79304 family with sequence similarity 13, member C FAM13C 220965 NM_001001971 /// NM_001143773 /// NM_001166698 /// NM_198215 /// XM_005269618 /// XM_005269619 /// XM_006717702 /// XM_006717703 214915_at AK021842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021842.1 /DEF=Homo sapiens cDNA FLJ11780 fis, clone HEMBA1005931, weakly similar to ZINC FINGER PROTEIN 83. /FEA=mRNA /DB_XREF=gi:10433110 /UG=Hs.279935 Homo sapiens cDNA FLJ11780 fis, clone HEMBA1005931, weakly similar to ZINC FINGER PROTEIN 83 AK021842 zinc finger protein 362 ZNF362 149076 NM_152493 /// XM_005270507 /// XM_005270508 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214916_x_at BG340548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG340548 /FEA=EST /DB_XREF=gi:13146986 /DB_XREF=est:602462113F1 /CLONE=IMAGE:4575051 /UG=Hs.301365 Human rearranged immunoglobulin heavy chain mRNA, partial cds BG340548 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 3-23 /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHA2 /// IGHG1 /// IGHG3 /// IGHM /// IGHV3-23 /// IGHV4-31 3493 /// 3494 /// 3500 /// 3502 /// 3507 /// 28396 /// 28442 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214917_at AK024252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024252.1 /DEF=Homo sapiens cDNA FLJ14190 fis, clone NT2RP2006534, moderately similar to 5-AMP-ACTIVATED PROTEIN KINASE, CATALYTIC ALPHA-1 CHAIN (EC 2.7.1.-). /FEA=mRNA /DB_XREF=gi:10436581 /UG=Hs.288546 Homo sapiens cDNA FLJ14190 fis, clone NT2RP2006534, moderately similar to 5-AMP-ACTIVATED PROTEIN KINASE, CATALYTIC ALPHA-1 CHAIN (EC 2.7.1.-) AK024252 protein kinase, AMP-activated, alpha 1 catalytic subunit PRKAA1 5562 NM_006251 /// NM_206907 /// XM_006714481 /// XM_006714482 0000187 // activation of MAPK activity // non-traceable author statement /// 0001666 // response to hypoxia // non-traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from sequence or structural similarity /// 0009631 // cold acclimation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from sequence or structural similarity /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0035404 // histone-serine phosphorylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045542 // positive regulation of cholesterol biosynthetic process // non-traceable author statement /// 0045821 // positive regulation of glycolytic process // inferred from sequence or structural similarity /// 0046318 // negative regulation of glucosylceramide biosynthetic process // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from sequence or structural similarity /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071417 // cellular response to organonitrogen compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity /// 2001274 // negative regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004679 // AMP-activated protein kinase activity // inferred from direct assay /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0035174 // histone serine kinase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047322 // [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from electronic annotation /// 0050405 // [acetyl-CoA carboxylase] kinase activity // inferred from electronic annotation 214918_at AK024911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024911.1 /DEF=Homo sapiens cDNA: FLJ21258 fis, clone COL01408. /FEA=mRNA /DB_XREF=gi:10437326 /UG=Hs.287652 Homo sapiens cDNA: FLJ21258 fis, clone COL01408 AK024911 heterogeneous nuclear ribonucleoprotein M HNRNPM 4670 NM_001297418 /// NM_005968 /// NM_031203 /// XM_005272478 /// XM_005272479 /// XM_005272480 /// XM_005272481 /// XM_005272482 /// XM_005272483 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214919_s_at R39094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R39094 /FEA=EST /DB_XREF=gi:796550 /DB_XREF=est:yf50c09.s1 /CLONE=IMAGE:25528 /UG=Hs.301226 KIAA1085 protein R39094 ankyrin repeat and KH domain containing 1 /// ANKHD1-EIF4EBP3 readthrough /// eukaryotic translation initiation factor 4E binding protein 3 ANKHD1 /// ANKHD1-EIF4EBP3 /// EIF4EBP3 8637 /// 54882 /// 404734 NM_001197030 /// NM_003732 /// NM_017747 /// NM_017978 /// NM_020690 /// NM_024668 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // non-traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation /// 0030371 // translation repressor activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 214920_at R33964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R33964 /FEA=EST /DB_XREF=gi:789822 /DB_XREF=est:yh74c03.r1 /CLONE=IMAGE:135460 /UG=Hs.288681 Homo sapiens cDNA FLJ11022 fis, clone PLACE1003771 R33964 thrombospondin, type I, domain containing 7A THSD7A 221981 NM_015204 /// XM_006715659 /// XM_006715660 /// XM_006715661 /// XM_006715662 0001525 // angiogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 214921_at U02632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02632.1 /DEF=Human calcium-activated potassium channel mRNA, partial cds. /FEA=mRNA /PROD=calcium-activated potassium channel /DB_XREF=gi:487427 /UG=Hs.297229 Human calcium-activated potassium channel mRNA, partial cds U02632 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 KCNMA1 3778 NM_001014797 /// NM_001161352 /// NM_001161353 /// NM_001271518 /// NM_001271519 /// NM_001271520 /// NM_001271521 /// NM_001271522 /// NM_002247 /// XM_005269776 /// XM_005269778 /// XM_005269779 /// XM_005269780 /// XM_005269781 /// XM_005269785 /// XM_005269787 /// XM_005269789 /// XM_005269792 /// XM_005269795 /// XM_005269796 /// XM_005269797 /// XM_005269800 /// XM_005269801 /// XM_005269803 /// XM_005269804 /// XM_006717821 /// XM_006717822 /// XM_006717823 /// XM_006717824 /// XM_006717825 /// XM_006717826 /// XM_006717827 /// XM_006717828 /// XM_006717829 /// XM_006717830 0001666 // response to hypoxia // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0006970 // response to osmotic stress // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030007 // cellular potassium ion homeostasis // inferred from direct assay /// 0032344 // regulation of aldosterone metabolic process // inferred from electronic annotation /// 0034465 // response to carbon monoxide // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045794 // negative regulation of cell volume // inferred from direct assay /// 0046541 // saliva secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060073 // micturition // inferred from direct assay /// 0060082 // eye blink reflex // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from direct assay /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from direct assay /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from mutant phenotype 214922_at BE567977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE567977 /FEA=EST /DB_XREF=gi:9811697 /DB_XREF=est:601341475F1 /CLONE=IMAGE:3683706 /UG=Hs.293633 Homo sapiens cDNA FLJ20765 fis, clone COL08282, highly similar to ZN41_HUMAN ZINC FINGER PROTEIN 41 BE567977 zinc finger protein 484 ZNF484 83744 NM_001007101 /// NM_001261458 /// NM_001261459 /// NM_001261460 /// NM_031486 /// XM_005252253 /// XM_006717299 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 214923_at AK001155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001155.1 /DEF=Homo sapiens cDNA FLJ10293 fis, clone NT2RM1000280, highly similar to VACUOLAR ATP SYNTHASE SUBUNIT D (EC 3.6.1.34). /FEA=mRNA /DB_XREF=gi:7022230 /UG=Hs.306415 Homo sapiens cDNA FLJ10293 fis, clone NT2RM1000280, highly similar to VACUOLAR ATP SYNTHASE SUBUNIT D (EC 3.6.1.34) AK001155 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D ATP6V1D 51382 NM_015994 0002011 // morphogenesis of an epithelial sheet // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0035750 // protein localization to myelin sheath abaxonal region // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0061512 // protein localization to cilium // inferred from mutant phenotype /// 0070830 // tight junction assembly // traceable author statement /// 0090002 // establishment of protein localization to plasma membrane // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 214924_s_at AK000754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000754.1 /DEF=Homo sapiens cDNA FLJ20747 fis, clone HEP05884, highly similar to J03068 Human DNF1552. /FEA=mRNA /DB_XREF=gi:7021038 /UG=Hs.6705 KIAA1042 protein AK000754 trafficking protein, kinesin binding 1 TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 214925_s_at AK026484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026484.1 /DEF=Homo sapiens cDNA: FLJ22831 fis, clone KAIA4161. /FEA=mRNA /DB_XREF=gi:10439356 /UG=Hs.321666 Homo sapiens cDNA: FLJ22831 fis, clone KAIA4161 AK026484 spectrin, alpha, non-erythrocytic 1 SPTAN1 6709 NM_001130438 /// NM_001195532 /// NM_003127 /// XM_006717245 /// XM_006717246 /// XM_006717247 /// XM_006717248 /// XM_006717249 /// XM_006717250 /// XM_006717251 /// XM_006717252 /// XM_006717253 /// XM_006717254 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214926_at AK026484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026484.1 /DEF=Homo sapiens cDNA: FLJ22831 fis, clone KAIA4161. /FEA=mRNA /DB_XREF=gi:10439356 /UG=Hs.321666 Homo sapiens cDNA: FLJ22831 fis, clone KAIA4161 AK026484 spectrin, alpha, non-erythrocytic 1 SPTAN1 6709 NM_001130438 /// NM_001195532 /// NM_003127 /// XM_006717245 /// XM_006717246 /// XM_006717247 /// XM_006717248 /// XM_006717249 /// XM_006717250 /// XM_006717251 /// XM_006717252 /// XM_006717253 /// XM_006717254 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 214927_at AL359052 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359052.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1968422. /FEA=mRNA /PROD=ITGBL1, integrin beta-like 1 /DB_XREF=gi:8518175 /UG=Hs.311054 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1968422 AL359052 integrin, beta-like 1 (with EGF-like repeat domains) ITGBL1 9358 NM_001271754 /// NM_001271755 /// NM_001271756 /// NM_004791 /// XM_005254100 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 214928_at AI915513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI915513 /FEA=EST /DB_XREF=gi:5635368 /DB_XREF=est:wg30a08.x1 /CLONE=IMAGE:2366582 /UG=Hs.6654 KIAA0657 protein AI915513 obscurin-like 1 OBSL1 23363 NM_001173408 /// NM_001173431 /// NM_015311 /// XM_005246421 /// XM_005246423 /// XM_005246424 /// XM_005246425 /// XM_005246427 /// XM_006712386 /// XM_006712387 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0050775 // positive regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0014704 // intercalated disc // traceable author statement /// 0030018 // Z disc // traceable author statement /// 0031430 // M band // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // traceable author statement /// 1990393 // 3M complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation 214929_s_at AL137384 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137384.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0126 (from clone DKFZp434M0126); partial cds. /FEA=mRNA /GEN=DKFZp434M0126 /PROD=hypothetical protein /DB_XREF=gi:6807914 /UG=Hs.6606 KIAA1109 protein AL137384 KIAA1109 KIAA1109 84162 NM_015312 /// NM_032202 /// XM_005263282 /// XM_005263283 /// XM_005263284 /// XM_005263285 /// XM_005263286 /// XM_005263287 /// XM_005263288 /// XM_005263289 /// XM_005263290 /// XM_005263291 /// XM_005263292 /// XM_006714342 /// XM_006714343 /// XM_006714344 0001558 // regulation of cell growth // non-traceable author statement /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214930_at AW449813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW449813 /FEA=EST /DB_XREF=gi:6990589 /DB_XREF=est:UI-H-BI3-akm-b-07-0-UI.s1 /CLONE=IMAGE:2734788 /UG=Hs.58009 KIAA0918 protein AW449813 SLIT and NTRK-like family, member 5 SLITRK5 26050 NM_015567 /// XM_005254038 /// XM_005254039 0007268 // synaptic transmission // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 214931_s_at AC005070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005070 /DEF=Homo sapiens BAC clone CTB-152G17 from 7q22-q31.1 /FEA=CDS_2 /DB_XREF=gi:3406049 /UG=Hs.78353 SFRS protein kinase 2 AC005070 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity 214932_at AL133620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133620.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F0621 (from clone DKFZp434F0621). /FEA=mRNA /GEN=DKFZp434F0621 /PROD=hypothetical protein /DB_XREF=gi:6599236 /UG=Hs.9873 likely homolog of rat kinase D-interacting substance of 220 kDa; KIAA1250 protein AL133620 kinase D-interacting substrate, 220kDa KIDINS220 57498 NM_020738 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 214933_at AA769818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA769818 /FEA=EST /DB_XREF=gi:2821056 /DB_XREF=est:ah81b03.s1 /CLONE=1321997 /UG=Hs.96253 calcium channel, voltage-dependent, PQ type, alpha 1A subunit AA769818 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit /// uncharacterized LOC100507353 CACNA1A /// LOC100507353 773 /// 100507353 NM_000068 /// NM_001127221 /// NM_001127222 /// NM_001174080 /// NM_023035 /// XR_109571 /// XR_133165 /// XR_172267 0000096 // sulfur amino acid metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014056 // regulation of acetylcholine secretion, neurotransmission // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021590 // cerebellum maturation // inferred from electronic annotation /// 0021679 // cerebellar molecular layer development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021750 // vestibular nucleus development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0032353 // negative regulation of hormone biosynthetic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042133 // neurotransmitter metabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060024 // rhythmic synaptic transmission // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // not recorded /// 0019905 // syntaxin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214934_at AW411030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW411030 /FEA=EST /DB_XREF=gi:6936571 /DB_XREF=est:fh09h11.y1 /CLONE=IMAGE:2964716 /UG=Hs.91471 ATPase, Class II, type 9B AW411030 ATPase, class II, type 9B ATP9B 374868 NM_198531 /// XM_005266690 /// XM_005266691 /// XM_005266692 /// XM_005266693 /// XM_005266694 /// XM_005266695 /// XM_006722447 /// XM_006722448 /// XM_006722449 /// XM_006722450 /// XR_245458 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0015917 // aminophospholipid transport // non-traceable author statement /// 0045332 // phospholipid translocation // non-traceable author statement /// 0072600 // establishment of protein localization to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015247 // aminophospholipid transporter activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214935_at BE794962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE794962 /FEA=EST /DB_XREF=gi:10216160 /DB_XREF=est:601589728F1 /CLONE=IMAGE:3943734 /UG=Hs.9877 hypothetical protein BE794962 interleukin 4 induced 1 /// nucleoporin 62kDa IL4I1 /// NUP62 23636 /// 259307 NM_001193357 /// NM_001258017 /// NM_001258018 /// NM_012346 /// NM_016553 /// NM_152899 /// NM_153718 /// NM_153719 /// NM_172374 /// NR_047577 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008645 // hexose transport // traceable author statement /// 0009755 // hormone-mediated signaling pathway // non-traceable author statement /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031074 // nucleocytoplasmic shuttling complex // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0046930 // pore complex // non-traceable author statement 0001716 // L-amino-acid oxidase activity // not recorded /// 0003682 // chromatin binding // non-traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017056 // structural constituent of nuclear pore // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from sequence or structural similarity /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from electronic annotation 214936_at AW298219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW298219 /FEA=EST /DB_XREF=gi:6704855 /DB_XREF=est:UI-H-BW0-ajt-f-04-0-UI.s1 /CLONE=IMAGE:2733055 /UG=Hs.99232 KIAA1016 protein AW298219 leucine-rich repeats and calponin homology (CH) domain containing 1 LRCH1 23143 NM_001164211 /// NM_001164213 /// NM_015116 214937_x_at AI924817 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI924817 /FEA=EST /DB_XREF=gi:5660781 /DB_XREF=est:wn23c11.x1 /CLONE=IMAGE:2446292 /UG=Hs.75737 pericentriolar material 1 AI924817 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 214938_x_at AF283771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF283771.2 /DEF=Homo sapiens clone TCBAP0774 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10281740 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 AF283771 high mobility group box 1 HMGB1 3146 NM_002128 /// XM_005266363 /// XM_005266365 /// XM_005266368 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001773 // myeloid dendritic cell activation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from expression pattern /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 2000426 // negative regulation of apoptotic cell clearance // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0042056 // chemoattractant activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 214939_x_at AB011399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011399 /DEF=Homo sapiens gene for AF-6, complete cds /FEA=CDS_2 /DB_XREF=gi:3452571 /UG=Hs.100469 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 AB011399 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 MLLT4 4301 NM_001040000 /// NM_001040001 /// NM_001207008 /// NM_001291964 /// NM_005936 /// XM_005266996 /// XM_005266997 /// XM_006715483 /// XM_006715484 /// XM_006715485 /// XM_006715486 /// XM_006715487 /// XM_006715488 /// XM_006715489 /// XM_006715490 /// XM_006715491 /// XM_006715492 /// XM_006715493 /// XM_006715494 /// XR_427971 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 214940_s_at AB018275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018275.1 /DEF=Homo sapiens mRNA for KIAA0732 protein, partial cds. /FEA=mRNA /GEN=KIAA0732 /PROD=KIAA0732 protein /DB_XREF=gi:3882184 /UG=Hs.20185 KIAA0732 protein AB018275 SMG6 nonsense mediated mRNA decay factor SMG6 23293 NM_001170957 /// NM_001256827 /// NM_001256828 /// NM_001282326 /// NM_017575 /// XM_005256569 /// XM_005256570 /// XM_005256571 /// XM_006721493 /// XM_006721494 /// XM_006721495 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from mutant phenotype /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005697 // telomerase holoenzyme complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from direct assay /// 0004521 // endoribonuclease activity // inferred from mutant phenotype /// 0004521 // endoribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214941_s_at AA675900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA675900 /FEA=EST /DB_XREF=gi:2775247 /DB_XREF=est:g02504r /CLONE=g02504 /UG=Hs.119325 Huntingtin-interacting protein A AA675900 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) PRPF40A 55660 NM_017892 /// XM_005246676 /// XM_005246677 /// XM_005246678 /// XM_005246679 0006397 // mRNA processing // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 214942_at D38491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38491.1 /DEF=Human mRNA for KIAA0117 gene, partial cds. /FEA=mRNA /GEN=KIAA0117 /DB_XREF=gi:559327 /UG=Hs.322478 KIAA0117 protein D38491 RNA binding motif protein 34 RBM34 23029 NM_001161533 /// NM_015014 /// NR_027762 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214943_s_at D38491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38491.1 /DEF=Human mRNA for KIAA0117 gene, partial cds. /FEA=mRNA /GEN=KIAA0117 /DB_XREF=gi:559327 /UG=Hs.322478 KIAA0117 protein D38491 AT rich interactive domain 4B (RBP1-like) /// RNA binding motif protein 34 ARID4B /// RBM34 23029 /// 51742 NM_001161533 /// NM_001206794 /// NM_015014 /// NM_016374 /// NM_031371 /// NR_027762 /// XM_005273160 /// XM_006711781 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation /// 0036124 // histone H3-K9 trimethylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214944_at AK001854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001854.1 /DEF=Homo sapiens cDNA FLJ10992 fis, clone PLACE1002073, weakly similar to ADENYLATE CYCLASE (EC 4.6.1.1). /FEA=mRNA /DB_XREF=gi:7023379 /UG=Hs.132339 Homo sapiens cDNA FLJ10992 fis, clone PLACE1002073, weakly similar to ADENYLATE CYCLASE (EC 4.6.1.1) AK001854 PH domain and leucine rich repeat protein phosphatase 2 PHLPP2 23035 NM_001289003 /// NM_015020 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214945_at AW514267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514267 /FEA=EST /DB_XREF=gi:7152273 /DB_XREF=est:hd74b08.x1 /CLONE=IMAGE:2915223 /UG=Hs.126779 KIAA0752 protein AW514267 family with sequence similarity 153, member A /// family with sequence similarity 153, member B /// family with sequence similarity 153, member C, pseudogene /// uncharacterized LOC100507387 /// uncharacterized LOC101928349 /// uncharacterized LOC101930363 FAM153A /// FAM153B /// FAM153C /// LOC100507387 /// LOC101928349 /// LOC101930363 202134 /// 285596 /// 653316 /// 100507387 /// 101928349 /// 101930363 NM_001079527 /// NM_001079529 /// NM_001265615 /// NM_173663 /// NR_038353 /// NR_038402 /// XM_005265889 /// XM_006714841 /// XM_006714842 /// XM_006714843 /// XM_006714844 /// XM_006714845 /// XM_006714846 /// XM_006714847 /// XM_006714848 /// XM_006714849 /// XM_006714850 /// XM_006714851 /// XM_006714852 /// XM_006714853 /// XM_006714854 /// XR_245305 /// XR_245307 /// XR_249910 /// XR_251928 /// XR_251930 /// XR_425934 /// XR_425935 /// XR_425938 /// XR_425939 /// XR_427819 /// XR_431948 214946_x_at AV728658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV728658 /FEA=EST /DB_XREF=gi:10838079 /DB_XREF=est:AV728658 /CLONE=HTCALE08 /UG=Hs.13273 KIAA0592 protein AV728658 family with sequence similarity 21, member A /// family with sequence similarity 21, member C /// uncharacterized LOC101930591 FAM21A /// FAM21C /// LOC101930591 253725 /// 387680 /// 101930591 NM_001005751 /// NM_001169106 /// NM_001169107 /// NM_001291398 /// NM_015262 /// NM_018232 /// XM_005269805 /// XM_005269806 /// XM_005269807 /// XM_005269808 /// XM_005269810 /// XM_006717831 /// XM_006717832 /// XR_247516 0006810 // transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay /// 0071203 // WASH complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 214947_at AF052146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052146.1 /DEF=Homo sapiens clone 24653 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360455 /UG=Hs.155085 Homo sapiens clone 24653 mRNA sequence AF052146 family with sequence similarity 105, member A FAM105A 54491 NM_019018 214948_s_at AL050136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050136.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L141 (from clone DKFZp586L141). /FEA=mRNA /DB_XREF=gi:4884346 /UG=Hs.140945 Homo sapiens mRNA; cDNA DKFZp586L141 (from clone DKFZp586L141) AL050136 TATA element modulatory factor 1 TMF1 7110 NM_007114 0001675 // acrosome assembly // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0032275 // luteinizing hormone secretion // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2000845 // positive regulation of testosterone secretion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214949_at AL050136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050136.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L141 (from clone DKFZp586L141). /FEA=mRNA /DB_XREF=gi:4884346 /UG=Hs.140945 Homo sapiens mRNA; cDNA DKFZp586L141 (from clone DKFZp586L141) AL050136 214950_at L39064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L39064 /DEF=Homo sapiens interleukin 9 receptor precursor (IL9R) gene, complete cds /FEA=mRNA /DB_XREF=gi:632992 /UG=Hs.1702 interleukin 9 receptor L39064 214951_at AL050358 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050358.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M1916 (from clone DKFZp564M1916); partial cds. /FEA=mRNA /GEN=DKFZp564M1916 /PROD=hypothetical protein /DB_XREF=gi:4914576 /UG=Hs.159481 UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T) AL050358 solute carrier family 26, member 10 SLC26A10 65012 NM_001018084 /// NM_133489 0006810 // transport // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015116 // sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 214952_at BF348061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF348061 /FEA=EST /DB_XREF=gi:11295656 /DB_XREF=est:602022610F1 /CLONE=IMAGE:4157907 /UG=Hs.167988 neural cell adhesion molecule 1 BF348061 neural cell adhesion molecule 1 NCAM1 4684 NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351 0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042802 // identical protein binding // inferred from physical interaction 214953_s_at X06989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06989.1 /DEF=Human mRNA for amyloid A4(751) protein. /FEA=mRNA /DB_XREF=gi:28720 /UG=Hs.177486 amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) X06989 amyloid beta (A4) precursor protein APP 351 NM_000484 /// NM_001136016 /// NM_001136129 /// NM_001136130 /// NM_001136131 /// NM_001204301 /// NM_001204302 /// NM_001204303 /// NM_201413 /// NM_201414 0000085 // mitotic G2 phase // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007617 // mating behavior // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008088 // axon cargo transport // inferred from sequence or structural similarity /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048669 // collateral sprouting in absence of injury // inferred from sequence or structural similarity /// 0050803 // regulation of synapse structure and activity // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051124 // synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from direct assay /// 0043198 // dendritic shaft // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from electronic annotation 214954_at BF977837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF977837 /FEA=EST /DB_XREF=gi:12345052 /DB_XREF=est:602148677F1 /CLONE=IMAGE:4307442 /UG=Hs.196647 KIAA0527 protein BF977837 sushi domain containing 5 SUSD5 26032 NM_015551 /// XM_005265034 /// XM_005265035 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005540 // hyaluronic acid binding // inferred from electronic annotation 214955_at AI912086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI912086 /FEA=EST /DB_XREF=gi:5631941 /DB_XREF=est:wd84f08.x1 /CLONE=IMAGE:2338311 /UG=Hs.194750 Human DNA sequence from clone 1170K4 on chromosome 22q12.2-13.1. Contains three novel genes, one of which codes for a Trypsin family protein with class A LDL receptor domains, and the IL2RB gene for Interleukin 2 Receptor, Beta (IL-2 Receptor, CD122 antig AI912086 transmembrane protease, serine 6 TMPRSS6 164656 NM_001289000 /// NM_001289001 /// NM_153609 /// XM_006724162 /// XM_006724163 0001525 // angiogenesis // non-traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042730 // fibrinolysis // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 214956_at AF090101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090101.1 /DEF=Homo sapiens clone IMAGE 30714. /FEA=mRNA /DB_XREF=gi:4063636 /UG=Hs.177837 Homo sapiens clone IMAGE 30714 AF090101 AP2 associated kinase 1 AAK1 22848 NM_014911 0006468 // protein phosphorylation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 214957_at BF594459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF594459 /FEA=EST /DB_XREF=gi:11686783 /DB_XREF=est:7i06g11.x1 /CLONE=IMAGE:3324740 /UG=Hs.2149 actin like protein BF594459 actin-like 8 ACTL8 81569 NM_030812 0030855 // epithelial cell differentiation // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 214958_s_at AK021738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021738.1 /DEF=Homo sapiens cDNA FLJ11676 fis, clone HEMBA1004752, highly similar to Homo sapiens mRNA for LAK-4p. /FEA=mRNA /DB_XREF=gi:10432982 /UG=Hs.322422 Homo sapiens cDNA FLJ11676 fis, clone HEMBA1004752, highly similar to Homo sapiens mRNA for LAK-4p AK021738 transmembrane channel-like 6 TMC6 11322 NM_001127198 /// NM_007267 /// XM_005256995 /// XM_005256996 /// XM_005256997 /// XM_005256998 /// XR_243632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 214959_s_at AF229253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229253.1 /DEF=Homo sapiens clone FIF N1 fibroblast growth factor 2-interacting factor (API5) mRNA, partial cds.; alternatively spliced. /FEA=mRNA /GEN=API5 /PROD=fibroblast growth factor 2-interacting factor /DB_XREF=gi:12656082 /UG=Hs.227913 API5-like 1 AF229253 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214960_at AF229253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229253.1 /DEF=Homo sapiens clone FIF N1 fibroblast growth factor 2-interacting factor (API5) mRNA, partial cds.; alternatively spliced. /FEA=mRNA /GEN=API5 /PROD=fibroblast growth factor 2-interacting factor /DB_XREF=gi:12656082 /UG=Hs.227913 API5-like 1 AF229253 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214961_at AI818409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI818409 /FEA=EST /DB_XREF=gi:5437488 /DB_XREF=est:wk78e08.x1 /CLONE=IMAGE:2421542 /UG=Hs.22201 KIAA0774 protein AI818409 microtubule associated tumor suppressor candidate 2 MTUS2 23281 NM_001033602 /// NM_015233 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 214962_s_at AK026236 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026236.1 /DEF=Homo sapiens cDNA: FLJ22583 fis, clone HSI02596. /FEA=mRNA /DB_XREF=gi:10439023 /UG=Hs.22559 KIAA0197 protein AK026236 nucleoporin 160kDa NUP160 23279 NM_015231 /// XM_006718170 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214963_at AK026236 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026236.1 /DEF=Homo sapiens cDNA: FLJ22583 fis, clone HSI02596. /FEA=mRNA /DB_XREF=gi:10439023 /UG=Hs.22559 KIAA0197 protein AK026236 nucleoporin 160kDa NUP160 23279 NM_015231 /// XM_006718170 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 214964_at AA554430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA554430 /FEA=EST /DB_XREF=gi:2324969 /DB_XREF=est:nl14f04.s1 /CLONE=IMAGE:1030303 /UG=Hs.269421 Homo sapiens cDNA FLJ14343 fis, clone THYRO1000916 AA554430 214965_at AF070574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070574.1 /DEF=Homo sapiens clone 24819 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387945 /UG=Hs.22316 Homo sapiens clone 24819 mRNA sequence AF070574 spermatogenesis associated 2-like SPATA2L 124044 NM_152339 /// XM_005256279 214966_at S40369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S40369.1 /DEF=glutamate receptor subunit=kainate receptor subunit human, hippocampus, mRNA, 2943 nt. /FEA=CDS /GEN=glutamate receptor subunit, EAA2, excitatory aminoacid receptor 2 /PROD=glutamate receptor subunit /DB_XREF=gi:251839 /UG=Hs.249141 Glutamate receptor subunit S40369 glutamate receptor, ionotropic, kainate 5 GRIK5 2901 NM_002088 /// XM_005258821 /// XM_005258822 /// XM_006723169 /// XM_006723170 /// XR_243925 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0031630 // regulation of synaptic vesicle fusion to presynaptic membrane // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0051649 // establishment of localization in cell // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008328 // ionotropic glutamate receptor complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 214967_at AU146983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146983 /FEA=EST /DB_XREF=gi:11008504 /DB_XREF=est:AU146983 /CLONE=HEMBB1002049 /UG=Hs.262212 Homo sapiens cDNA FLJ12055 fis, clone HEMBB1002049 AU146983 214968_at AV694312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV694312 /FEA=EST /DB_XREF=gi:10296175 /DB_XREF=est:AV694312 /CLONE=GKCELG01 /UG=Hs.250638 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 152428 AV694312 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 DDX51 317781 NM_175066 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 214969_at AF251442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF251442.1 /DEF=Homo sapiens mixed lineage kinase MLK1 mRNA, partial cds. /FEA=mRNA /PROD=mixed lineage kinase MLK1 /DB_XREF=gi:12005723 /UG=Hs.258964 Homo sapiens mixed lineage kinase MLK1 mRNA, partial cds AF251442 mitogen-activated protein kinase kinase kinase 9 MAP3K9 4293 NM_001284230 /// NM_001284231 /// NM_001284232 /// NM_033141 /// XM_005267683 /// XM_006720149 /// XM_006720150 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007256 // activation of JNKK activity // inferred from sequence or structural similarity /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004706 // JUN kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004708 // MAP kinase kinase activity // non-traceable author statement /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 214970_s_at X17247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X17247.1 /DEF=Human mRNA for sialyltransferase (CMP-N-acetylneuraminate-beta-galactoside alpha-2,6-sialyltransferase) (EC 2.4.99.1). /FEA=mRNA /DB_XREF=gi:36461 /UG=Hs.2554 sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) X17247 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ST6GAL1 6480 NM_003032 /// NM_173216 /// NM_173217 /// XM_005247717 /// XM_005247719 /// XM_005247720 /// XM_006713734 0006054 // N-acetylneuraminate metabolic process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003835 // beta-galactoside alpha-2,6-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 214971_s_at AV695711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV695711 /FEA=EST /DB_XREF=gi:10297574 /DB_XREF=est:AV695711 /CLONE=GKCDXA06 /UG=Hs.2554 sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) AV695711 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ST6GAL1 6480 NM_003032 /// NM_173216 /// NM_173217 /// XM_005247717 /// XM_005247719 /// XM_005247720 /// XM_006713734 0006054 // N-acetylneuraminate metabolic process // inferred from direct assay /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003835 // beta-galactoside alpha-2,6-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 214972_at AU144791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144791 /FEA=EST /DB_XREF=gi:11006312 /DB_XREF=est:AU144791 /CLONE=HEMBA1002971 /UG=Hs.274237 Homo sapiens cDNA FLJ10126 fis, clone HEMBA1002971 AU144791 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 /// XR_246060 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010616 // negative regulation of cardiac muscle adaptation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031343 // positive regulation of cell killing // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043243 // positive regulation of protein complex disassembly // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060051 // negative regulation of protein glycosylation // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0070265 // necrotic cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 214973_x_at AJ275469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275469 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 2, cell E 172 /FEA=CDS /DB_XREF=gi:7573243 /UG=Hs.272366 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 2, cell E 172 AJ275469 immunoglobulin heavy constant delta IGHD 3495 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 214974_x_at AK026546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026546.1 /DEF=Homo sapiens cDNA: FLJ22893 fis, clone KAT04792. /FEA=mRNA /DB_XREF=gi:10439427 /UG=Hs.287716 Homo sapiens cDNA: FLJ22893 fis, clone KAT04792 AK026546 chemokine (C-X-C motif) ligand 5 CXCL5 6374 NM_002994 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 214975_s_at AK001816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001816.1 /DEF=Homo sapiens cDNA FLJ10954 fis, clone PLACE1000383, highly similar to Homo sapiens mRNA for MTMR1 protein. /FEA=mRNA /DB_XREF=gi:7023321 /UG=Hs.311755 Homo sapiens cDNA FLJ10954 fis, clone PLACE1000383, highly similar to Homo sapiens mRNA for MTMR1 protein AK001816 myotubularin related protein 1 MTMR1 8776 NM_003828 /// NM_176789 /// XM_005274765 /// XM_005274766 /// XM_005274767 /// XM_005274768 /// XM_006724854 /// XM_006724855 /// XM_006724856 /// XR_247319 /// XR_430557 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from sequence or structural similarity /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 214976_at AI554467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI554467 /FEA=EST /DB_XREF=gi:4486830 /DB_XREF=est:tq11h03.x1 /CLONE=IMAGE:2208533 /UG=Hs.306856 Homo sapiens cDNA: FLJ22848 fis, clone KAIA897 AI554467 ribosomal protein L13 /// small nucleolar RNA, C/D box 68 RPL13 /// SNORD68 6137 /// 606500 NM_000977 /// NM_001243130 /// NM_001243131 /// NM_033251 /// NR_002450 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022626 // cytosolic ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214977_at AK023852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023852.1 /DEF=Homo sapiens cDNA FLJ13790 fis, clone THYRO1000026. /FEA=mRNA /DB_XREF=gi:10435915 /UG=Hs.301407 Homo sapiens cDNA FLJ13790 fis, clone THYRO1000026 AK023852 214978_s_at AK023365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023365.1 /DEF=Homo sapiens cDNA FLJ13303 fis, clone OVARC1001372, highly similar to Homo sapiens liprin-alpha4 mRNA. /FEA=mRNA /DB_XREF=gi:10435269 /UG=Hs.300704 Homo sapiens cDNA FLJ13303 fis, clone OVARC1001372, highly similar to Homo sapiens liprin-alpha4 mRNA AK023365 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 PPFIA4 8497 NM_015053 /// XM_005245553 /// XM_006711584 /// XM_006711585 /// XM_006711586 /// XM_006711587 /// XM_006711588 /// XM_006711589 /// XM_006711590 /// XM_006711591 /// XR_426801 /// XR_426802 /// XR_426803 /// XR_426804 0007154 // cell communication // non-traceable author statement 0005622 // intracellular // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 214979_at AK000791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000791.1 /DEF=Homo sapiens cDNA FLJ20784 fis, clone COL02880, highly similar to AF085692 Homo sapiens multidrug resistance-associated protein. /FEA=mRNA /DB_XREF=gi:7021094 /UG=Hs.298107 Homo sapiens cDNA FLJ20784 fis, clone COL02880, highly similar to AF085692 Homo sapiens multidrug resistance-associated protein AK000791 214980_at AF037219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF037219.1 /DEF=Homo sapiens PIX1 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4090971 /UG=Hs.301667 Homo sapiens mRNA; cDNA DKFZp566I043 (from clone DKFZp566I043) AF037219 ubiquitin protein ligase E3A UBE3A 7337 NM_000462 /// NM_130838 /// NM_130839 /// XM_005268267 /// XM_005268268 /// XM_005268269 /// XM_005268270 /// XM_005268271 /// XM_006720673 /// XM_006720674 /// XM_006720675 /// XM_006720676 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // not recorded /// 0035037 // sperm entry // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 214981_at AW137148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW137148 /FEA=EST /DB_XREF=gi:6141281 /DB_XREF=est:UI-H-BI1-acq-a-04-0-UI.s1 /CLONE=IMAGE:2715150 /UG=Hs.306593 Homo sapiens cDNA FLJ11382 fis, clone HEMBA1000504 AW137148 periostin, osteoblast specific factor POSTN 10631 NM_001135934 /// NM_001135935 /// NM_001135936 /// NM_001286665 /// NM_001286666 /// NM_001286667 /// NM_006475 /// XM_005266231 /// XM_005266232 0001501 // skeletal system development // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from sequence or structural similarity 214982_at AK021418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021418.1 /DEF=Homo sapiens cDNA FLJ11356 fis, clone HEMBA1000150, highly similar to Homo sapiens putative RNA helicase mRNA. /FEA=mRNA /DB_XREF=gi:10432597 /UG=Hs.306592 Homo sapiens cDNA FLJ11356 fis, clone HEMBA1000150, highly similar to Homo sapiens putative RNA helicase mRNA AK021418 U5 small nuclear ribonucleoprotein 200 kDa helicase-like /// small nuclear ribonucleoprotein 200kDa (U5) LOC101929240 /// SNRNP200 23020 /// 101929240 NM_014014 /// XR_243770 /// XR_253745 /// XR_424859 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 214983_at AL080135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080135.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I143 (from clone DKFZp434I143). /FEA=mRNA /DB_XREF=gi:5262576 /UG=Hs.45068 hypothetical protein DKFZp434I143 AL080135 testis-specific transcript, Y-linked 15 (non-protein coding) TTTY15 64595 NR_001545 214984_at AC003007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003007 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-61E3 /FEA=mRNA_1 /DB_XREF=gi:2911728 /UG=Hs.325520 Homo sapiens IMAA mRNA for hLAT1-3TM, complete cds AC003007 putative L-type amino acid transporter 1-like protein IMAA-like /// solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1 /// SMG1 pseudogene 3 LOC101060604 /// SLC7A5P1 /// SMG1P3 81893 /// 100271836 /// 101060604 NM_031211 /// NR_002593 /// NR_027155 /// XM_005276494 /// XM_006726608 /// XM_006726609 0003333 // amino acid transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation 214985_at AF070571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070571.1 /DEF=Homo sapiens clone 24739 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387940 /UG=Hs.44690 Homo sapiens clone 24739 mRNA sequence AF070571 exostosin glycosyltransferase 1 EXT1 2131 NM_000127 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0072498 // embryonic skeletal joint development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from sequence or structural similarity /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // inferred from sequence or structural similarity /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement 214986_x_at U37221 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U37221.1 /DEF=Human cyclophilin-like protein mRNA, partial cds. /FEA=mRNA /PROD=cyclophilin-like protein /DB_XREF=gi:1199601 /UG=Hs.93523 peptidylprolyl isomerase (cyclophilin)-like 2 U37221 peptidylprolyl isomerase (cyclophilin)-like 2 PPIL2 23759 NM_014337 /// NM_148175 /// NM_148176 /// XM_005261447 /// XM_005261448 /// XM_006724197 /// XM_006724198 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 214987_at AL049449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049449.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1722 (from clone DKFZp586B1722). /FEA=mRNA /DB_XREF=gi:4500234 /UG=Hs.80720 Homo sapiens mRNA; cDNA DKFZp586B1722 (from clone DKFZp586B1722) AL049449 GRB2-associated binding protein 1 GAB1 2549 NM_002039 /// NM_207123 /// XM_005262881 /// XM_005262882 /// XM_006714167 /// XM_006714168 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 214988_s_at X63071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63071.1 /DEF=H.sapiens mRNA for novel DNA binding protein. /FEA=mRNA /GEN=DBP-5 /PROD=DBP-5 protein /DB_XREF=gi:30487 /UG=Hs.92909 SON DNA binding protein X63071 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 214989_x_at BC000969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000969.2 /DEF=Homo sapiens, clone IMAGE:3446800, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3446800) /DB_XREF=gi:12803023 /UG=Hs.86149 phosphoinositol 3-phosphate-binding protein-2 BC000969 214990_at AC004472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004472 /DEF=Homo sapiens chromosome 9, P1 clone 11659 /FEA=CDS_3 /DB_XREF=gi:2984582 /UG=Hs.85044 Homo sapiens chromosome 9, P1 clone 11659 AC004472 phosphatidylinositol glycan anchor biosynthesis, class O PIGO 84720 NM_001201484 /// NM_032634 /// NM_152850 /// XM_005251619 /// XR_242515 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 214991_s_at AC004472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004472 /DEF=Homo sapiens chromosome 9, P1 clone 11659 /FEA=CDS_3 /DB_XREF=gi:2984582 /UG=Hs.85044 Homo sapiens chromosome 9, P1 clone 11659 AC004472 phosphatidylinositol glycan anchor biosynthesis, class O PIGO 84720 NM_001201484 /// NM_032634 /// NM_152850 /// XM_005251619 /// XR_242515 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 214992_s_at AD000092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AD000092 /DEF=Homo sapiens DNA from chromosome 19p13.2 cosmids R31240, R30272 and R28549 containing the EKLF, GCDH, CRTC, and RAD23A genes, genomic sequence /FEA=CDS_1 /DB_XREF=gi:1905905 /UG=Hs.307251 Homo sapiens DNA from chromosome 19p13.2 cosmids R31240, R30272 and R28549 containing the EKLF, GCDH, CRTC, and RAD23A genes, genomic sequence AD000092 deoxyribonuclease II, lysosomal DNASE2 1777 NM_001375 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // inferred from electronic annotation /// 0004531 // deoxyribonuclease II activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation 214993_at AF070642 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070642.1 /DEF=Homo sapiens clone 24488 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283915 /UG=Hs.323815 Homo sapiens clone 24488 mRNA sequence AF070642 aspartate beta-hydroxylase domain containing 1 ASPHD1 253982 NM_181718 /// NM_198907 /// XR_243272 /// XR_429675 0018193 // peptidyl-amino acid modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 214994_at BF508948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508948 /FEA=EST /DB_XREF=gi:11592246 /DB_XREF=est:UI-H-BI4-aos-g-01-0-UI.s1 /CLONE=IMAGE:3086016 /UG=Hs.250619 phorbolin-like protein MDS019 BF508948 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F APOBEC3F 200316 NM_001006666 /// NM_145298 /// XR_244357 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016553 // base conversion or substitution editing // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030895 // apolipoprotein B mRNA editing enzyme complex // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 214995_s_at BF508948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508948 /FEA=EST /DB_XREF=gi:11592246 /DB_XREF=est:UI-H-BI4-aos-g-01-0-UI.s1 /CLONE=IMAGE:3086016 /UG=Hs.250619 phorbolin-like protein MDS019 BF508948 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F /// apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G APOBEC3F /// APOBEC3G 60489 /// 200316 NM_001006666 /// NM_021822 /// NM_145298 /// XM_006724290 /// XR_244357 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016553 // base conversion or substitution editing // traceable author statement /// 0016553 // base conversion or substitution editing // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay /// 0080111 // DNA demethylation // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030895 // apolipoprotein B mRNA editing enzyme complex // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from direct assay 214996_at AL079294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079294.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 362780. /FEA=mRNA /DB_XREF=gi:5102751 /UG=Hs.29952 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 362780 AL079294 214997_at AW675473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW675473 /FEA=EST /DB_XREF=gi:7540699 /DB_XREF=est:ba49g05.x1 /CLONE=IMAGE:2899928 /UG=Hs.101916 Homo sapiens mRNA; cDNA DKFZp564K133 (from clone DKFZp564K133) AW675473 suppressor of cancer cell invasion SCAI 286205 NM_001144877 /// NM_173690 /// XR_428524 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 214998_at AF090100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090100.1 /DEF=Homo sapiens clone IMAGE 23915. /FEA=mRNA /DB_XREF=gi:4063635 /UG=Hs.170241 Homo sapiens clone IMAGE 23915 AF090100 AP2 associated kinase 1 AAK1 22848 NM_014911 0006468 // protein phosphorylation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0030136 // clathrin-coated vesicle // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay 214999_s_at AW243089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW243089 /FEA=EST /DB_XREF=gi:6576882 /DB_XREF=est:xm92c10.x1 /CLONE=IMAGE:2691666 /UG=Hs.119004 KIAA0665 gene product AW243089 RAB11 family interacting protein 3 (class II) RAB11FIP3 9727 NM_001142272 /// NM_014700 /// XM_005255713 /// XM_005255714 /// XM_005255715 /// XM_005255717 /// XM_005255718 /// XM_006720987 /// XM_006720988 /// XM_006725242 /// XM_006725243 /// XM_006725244 /// XM_006725245 /// XM_006725246 /// XM_006725247 /// XM_006725248 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // non-traceable author statement /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215000_s_at AL117593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117593.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G082 (from clone DKFZp564G082). /FEA=mRNA /DB_XREF=gi:5912157 /UG=Hs.103419 fasciculation and elongation protein zeta 2 (zygin II) AL117593 fasciculation and elongation protein zeta 2 (zygin II) FEZ2 9637 NM_001042548 /// NM_005102 /// XM_006712153 /// XR_244972 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005515 // protein binding // inferred from physical interaction 215001_s_at AL161952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161952.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0813 (from clone DKFZp434M0813); partial cds. /FEA=mRNA /GEN=DKFZp434M0813 /PROD=hypothetical protein /DB_XREF=gi:7328002 /UG=Hs.170171 glutamate-ammonia ligase (glutamine synthase) AL161952 glutamate-ammonia ligase GLUL 2752 NM_001033044 /// NM_001033056 /// NM_002065 /// XM_006711278 0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006542 // glutamine biosynthetic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045503 // dynein light chain binding // inferred from electronic annotation 215002_at BE000837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE000837 /FEA=EST /DB_XREF=gi:8261070 /DB_XREF=est:RC2-BN0074-090300-014-c12 /UG=Hs.110613 KIAA0220 protein BE000837 nuclear pore complex-interacting protein family member B4-like /// nuclear pore complex interacting protein pseudogene /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member B11 /// nuclear pore complex interacting protein family, member B3 /// nuclear pore complex interacting protein family, member B4 /// nuclear pore complex interacting protein family, member B5 /// nuclear pore complex interacting protein family, member B8 LOC101929910 /// LOC613037 /// NPIPA5 /// NPIPB11 /// NPIPB3 /// NPIPB4 /// NPIPB5 /// NPIPB8 23117 /// 440345 /// 613037 /// 728734 /// 728888 /// 100132247 /// 100288332 /// 101929910 NM_001135865 /// NM_001277325 /// NM_130464 /// NR_002555 /// XM_001132754 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005255749 /// XM_005255750 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006721108 /// XM_006721110 /// XM_006721111 /// XM_006721112 /// XM_006721113 /// XM_006721114 /// XM_006721115 /// XM_006721116 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006726610 /// XM_006726615 /// XM_006726616 /// XR_433240 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215003_at AA921844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA921844 /FEA=EST /DB_XREF=gi:3069153 /DB_XREF=est:om44c06.s1 /CLONE=IMAGE:1543882 /UG=Hs.106311 DiGeorge syndrome gene A AA921844 DiGeorge syndrome critical region gene 9 (non-protein coding) DGCR9 25787 NR_024159 215004_s_at AC004475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004475 /DEF=Homo sapiens chromosome 19, cosmid F23858 /FEA=CDS /DB_XREF=gi:2988396 /UG=Hs.15075 hypothetical protein DKFZp434E2216 AC004475 SURP and G patch domain containing 1 SUGP1 57794 NM_021164 /// NM_172231 /// NM_182812 /// XM_005260002 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215005_at AV723666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV723666 /FEA=EST /DB_XREF=gi:10827293 /DB_XREF=est:AV723666 /CLONE=HTBABA11 /UG=Hs.140950 hypothetical protein AV723666 N-terminal EF-hand calcium binding protein 2 NECAB2 54550 NM_019065 /// XM_006721200 0007165 // signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215006_at AK023816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023816.1 /DEF=Homo sapiens cDNA FLJ13754 fis, clone PLACE3000362. /FEA=mRNA /DB_XREF=gi:10435865 /UG=Hs.136233 Homo sapiens cDNA FLJ13754 fis, clone PLACE3000362 AK023816 215008_at AA582404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA582404 /FEA=EST /DB_XREF=gi:2359764 /DB_XREF=est:nn49g08.s1 /CLONE=IMAGE:1087262 /UG=Hs.154296 tolloid-like 2 AA582404 tolloid-like 2 TLL2 7093 NM_012465 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215009_s_at U92014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U92014.1 /DEF=Human clone 121711 defective mariner transposon Hsmar2 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2052456 /UG=Hs.153527 Homo sapiens pTM5 mariner-like transposon mRNA, partial sequence U92014 THAP9 antisense RNA 1 THAP9-AS1 100499177 NR_034075 /// NR_034076 /// NR_034077 215010_s_at AJ006701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ006701.1 /DEF=Homo sapiens mRNA for putative serinethreonine protein kinase, partial. /FEA=mRNA /PROD=putative serinethreonine protein kinase /DB_XREF=gi:3217027 /UG=Hs.170819 serinethreonine kinase 29 AJ006701 BR serine/threonine kinase 2 BRSK2 9024 NM_001256627 /// NM_001256629 /// NM_001256630 /// NM_001282218 /// NM_003957 /// NR_046331 /// XM_005253218 /// XM_005253220 /// XM_006718374 /// XM_006718375 /// XM_006718376 /// XM_006718377 /// XM_006718378 /// XM_006718379 /// XR_242831 /// XR_428859 /// XR_428860 /// XR_428861 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006887 // exocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from direct assay /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity 215011_at AJ006835 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ006835.1 /DEF=Homo sapiens RNA transcript from U17 small nucleolar RNA host gene, variant U17HG-AB. /FEA=mRNA /DB_XREF=gi:3236105 /UG=Hs.196769 RNA, U17D small nucleolar AJ006835 small nucleolar RNA host gene 3 (non-protein coding) /// small nucleolar RNA, H/ACA box 73A SNHG3 /// SNORA73A 6080 /// 8420 NR_002907 /// NR_002909 /// NR_036473 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032853 // positive regulation of Ran GTPase activity // inferred from direct assay /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay 215012_at AU144775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144775 /FEA=EST /DB_XREF=gi:11006296 /DB_XREF=est:AU144775 /CLONE=HEMBA1002935 /UG=Hs.172329 KIAA0576 protein AU144775 zinc finger protein 451 ZNF451 26036 NM_001031623 /// NM_001257273 /// NM_015555 /// XM_005248994 /// XR_241885 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215013_s_at AK023845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023845.1 /DEF=Homo sapiens cDNA FLJ13783 fis, clone PLACE4000558, weakly similar to PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE FAF (EC 3.1.2.15). /FEA=mRNA /DB_XREF=gi:10435905 /UG=Hs.180948 KIAA0729 protein AK023845 ubiquitin specific peptidase 34 USP34 9736 NM_014709 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0001671 // ATPase activator activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 215014_at AL512727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512727.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547P042 (from clone DKFZp547P042). /FEA=mRNA /DB_XREF=gi:12224870 /UG=Hs.232127 Homo sapiens mRNA; cDNA DKFZp547P042 (from clone DKFZp547P042) AL512727 potassium voltage-gated channel, Shal-related subfamily, member 3 KCND3 3752 NM_004980 /// NM_172198 /// XM_005270851 /// XM_006710629 /// XM_006710630 /// XM_006710631 /// XM_006710632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0086009 // membrane repolarization // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005250 // A-type (transient outward) potassium channel activity // not recorded /// 0005250 // A-type (transient outward) potassium channel activity // inferred from direct assay /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215015_at AA319460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA319460 /FEA=EST /DB_XREF=gi:1971807 /DB_XREF=est:EST21712 /UG=Hs.204166 Human clone 295, 5cM region surrounding hepatocyte nuclear factor-1aMODY3 mRNA AA319460 coiled-coil domain containing 64 CCDC64 92558 NM_207311 /// XM_005253991 /// XM_006719694 /// XM_006719695 /// XM_006719696 /// XM_006719697 /// XR_429121 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0055107 // Golgi to secretory granule transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0034452 // dynactin binding // inferred from sequence or structural similarity 215016_x_at BC004912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004912.1 /DEF=Homo sapiens, clone IMAGE:3534745, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3534745) /DB_XREF=gi:13436208 /UG=Hs.198689 KIAA0728 protein BC004912 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 215017_s_at AW270932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW270932 /FEA=EST /DB_XREF=gi:6657962 /DB_XREF=est:xs06c12.x1 /CLONE=IMAGE:2768854 /UG=Hs.239681 hypothetical protein FLJ20275 AW270932 formin binding protein 1-like FNBP1L 54874 NM_001024948 /// NM_001164473 /// NM_017737 /// XM_006710707 0006897 // endocytosis // inferred from electronic annotation /// 0006900 // membrane budding // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010324 // membrane invagination // inferred from direct assay /// 0016050 // vesicle organization // inferred from direct assay /// 0030050 // vesicle transport along actin filament // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0072583 // clathrin-mediated endocytosis // inferred from direct assay /// 0097320 // membrane tubulation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 215018_at AB051518 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051518.1 /DEF=Homo sapiens mRNA for KIAA1731 protein, partial cds. /FEA=mRNA /GEN=KIAA1731 /PROD=KIAA1731 protein /DB_XREF=gi:12698006 /UG=Hs.249959 Homo sapiens mRNA for KIAA1731 protein, partial cds AB051518 KIAA1731 KIAA1731 85459 NM_033395 /// XM_005274366 /// XM_005274367 /// XM_005274368 /// XM_006718930 /// XM_006718931 /// XM_006718932 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay 215019_x_at AW474158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW474158 /FEA=EST /DB_XREF=gi:7044264 /DB_XREF=est:xy11f01.x1 /CLONE=IMAGE:2852857 /UG=Hs.249479 Homo sapiens cDNA FLJ13367 fis, clone PLACE1000583, weakly similar to ZINC FINGER PROTEIN 83 AW474158 zinc finger protein 528 ZNF528 84436 NM_032423 /// XM_005259316 /// XM_005259323 /// XM_005259324 /// XM_006723417 /// XM_006723418 /// XM_006723419 /// XM_006723420 /// XM_006723421 /// XM_006723422 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215020_at AF123462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF123462 /DEF=Homo sapiens BAC526N18 neurexin III gene, partial cds /FEA=CDS /DB_XREF=gi:4240565 /UG=Hs.247837 Homo sapiens BAC526N18 neurexin III gene, partial cds AF123462 neurexin 3 NRXN3 9369 NM_001105250 /// NM_001272020 /// NM_004796 /// NM_138970 /// NR_073546 /// NR_073547 /// XM_005268218 /// XM_006720322 /// XM_006720323 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007612 // learning // inferred from genetic interaction /// 0030534 // adult behavior // inferred from genetic interaction /// 0035176 // social behavior // inferred from genetic interaction /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0071625 // vocalization behavior // inferred from genetic interaction /// 0090129 // positive regulation of synapse maturation // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // traceable author statement /// 0097109 // neuroligin family protein binding // traceable author statement 215021_s_at AF123462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF123462 /DEF=Homo sapiens BAC526N18 neurexin III gene, partial cds /FEA=CDS /DB_XREF=gi:4240565 /UG=Hs.247837 Homo sapiens BAC526N18 neurexin III gene, partial cds AF123462 neurexin 3 NRXN3 9369 NM_001105250 /// NM_001272020 /// NM_004796 /// NM_138970 /// NR_073546 /// NR_073547 /// XM_005268218 /// XM_006720322 /// XM_006720323 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007612 // learning // inferred from genetic interaction /// 0030534 // adult behavior // inferred from genetic interaction /// 0035176 // social behavior // inferred from genetic interaction /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0071625 // vocalization behavior // inferred from genetic interaction /// 0090129 // positive regulation of synapse maturation // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // traceable author statement /// 0097109 // neuroligin family protein binding // traceable author statement 215022_x_at BG429214 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG429214 /FEA=EST /DB_XREF=gi:13335720 /DB_XREF=est:602498083F1 /CLONE=IMAGE:4611836 /UG=Hs.258144 zinc finger protein 33b (KOX 31) BG429214 zinc finger protein 33B ZNF33B 7582 NM_006955 /// XM_005271825 /// XM_006717964 /// XM_006717965 /// XM_006717966 /// XM_006717967 /// XM_006717968 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215023_s_at AC000064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC000064 /DEF=Human BAC clone RG083M05 from 7q21-7q22 /FEA=CDS_1 /DB_XREF=gi:1669369 /UG=Hs.296258 Human BAC clone RG083M05 from 7q21-7q22 AC000064 peroxisomal biogenesis factor 1 PEX1 5189 NM_000466 /// NM_001282677 /// NM_001282678 /// XM_005250429 /// XM_005250433 /// XR_242246 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0060152 // microtubule-based peroxisome localization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from mutant phenotype 215024_at AK000993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000993.1 /DEF=Homo sapiens cDNA FLJ10131 fis, clone HEMBA1003041. /FEA=mRNA /DB_XREF=gi:7021996 /UG=Hs.274128 Homo sapiens cDNA FLJ10131 fis, clone HEMBA1003041 AK000993 CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) CCZ1B 221960 NM_198097 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 215025_at S76476 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S76476.1 /DEF=trkC {alternatively spliced} human, brain, mRNA, 2225 nt. /FEA=mRNA /GEN=trkC /DB_XREF=gi:913723 /UG=Hs.26776 neurotrophic tyrosine kinase, receptor, type 3 S76476 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 215026_x_at U81961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U81961 /DEF=Homo sapiens amiloride-sensitive epithelial sodium channel alpha subunit alpha ENaC-1 and alpha ENaC-2 (SCNN1A) genes, alternatively spliced, partial cds /FEA=CDS_1 /DB_XREF=gi:2654468 /UG=Hs.2794 sodium channel, nonvoltage-gated 1 alpha U81961 sodium channel, non-voltage-gated 1 alpha subunit SCNN1A 6337 NM_001038 /// NM_001159575 /// NM_001159576 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0034706 // sodium channel complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 215027_at U79275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79275.1 /DEF=Human clone 23947 mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1710242 /UG=Hs.27414 hypothetical protein U79275 Rap guanine nucleotide exchange factor (GEF) 3 RAPGEF3 10411 NM_001098531 /// NM_001098532 /// NM_006105 /// XM_005268569 /// XM_005268570 /// XM_005268571 /// XM_006719197 /// XR_429071 0001525 // angiogenesis // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030822 // positive regulation of cAMP catabolic process // non-traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from direct assay /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0030552 // cAMP binding // inferred from electronic annotation 215028_at AB002438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002438.1 /DEF=Homo sapiens mRNA from chromosome 5q21-22, clone:FBR89. /FEA=mRNA /DB_XREF=gi:2943813 /UG=Hs.29596 Homo sapiens mRNA from chromosome 5q21-22, clone:FBR89 AB002438 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A SEMA6A 57556 NM_020796 /// XM_005272041 /// XM_005272042 /// XM_006714663 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 2001224 // positive regulation of neuron migration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // non-traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 215029_at AL117451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117451.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586E2317 (from clone DKFZp586E2317). /FEA=mRNA /DB_XREF=gi:5911901 /UG=Hs.293563 Homo sapiens mRNA; cDNA DKFZp586E2317 (from clone DKFZp586E2317) AL117451 215030_at AK023187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023187.1 /DEF=Homo sapiens cDNA FLJ13125 fis, clone NT2RP3002877. /FEA=mRNA /DB_XREF=gi:10435001 /UG=Hs.287551 Homo sapiens cDNA FLJ13125 fis, clone NT2RP3002877 AK023187 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 215031_x_at BG420893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG420893 /FEA=EST /DB_XREF=gi:13327412 /DB_XREF=est:602451114F1 /CLONE=IMAGE:4589691 /UG=Hs.69554 hypothetical protein FLJ20552 BG420893 ring finger protein 126 RNF126 55658 NM_017876 /// NM_194460 /// XM_005259594 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215032_at AK022442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022442.1 /DEF=Homo sapiens cDNA FLJ12380 fis, clone MAMMA1002556. /FEA=mRNA /DB_XREF=gi:10433838 /UG=Hs.300934 Homo sapiens cDNA FLJ12380 fis, clone MAMMA1002556 AK022442 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215033_at AI189753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189753 /FEA=EST /DB_XREF=gi:3740962 /DB_XREF=est:qd33a01.x1 /CLONE=IMAGE:1725480 /UG=Hs.306643 Homo sapiens cDNA FLJ13302 fis, clone OVARC1001357 AI189753 transmembrane 4 L six family member 1 TM4SF1 4071 NM_014220 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215034_s_at AI189753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189753 /FEA=EST /DB_XREF=gi:3740962 /DB_XREF=est:qd33a01.x1 /CLONE=IMAGE:1725480 /UG=Hs.306643 Homo sapiens cDNA FLJ13302 fis, clone OVARC1001357 AI189753 transmembrane 4 L six family member 1 TM4SF1 4071 NM_014220 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215035_at AI952772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI952772 /FEA=EST /DB_XREF=gi:5745082 /DB_XREF=est:wr50d05.x1 /CLONE=IMAGE:2491113 /UG=Hs.300865 Homo sapiens clone BCSynL38 immunoglobulin lambda light chain variable region mRNA, partial cds AI952772 immunoglobulin lambda variable 6-57 IGLV6-57 28778 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215036_at AI952772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI952772 /FEA=EST /DB_XREF=gi:5745082 /DB_XREF=est:wr50d05.x1 /CLONE=IMAGE:2491113 /UG=Hs.300865 Homo sapiens clone BCSynL38 immunoglobulin lambda light chain variable region mRNA, partial cds AI952772 215037_s_at U72398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U72398 /DEF=Human Bcl-x beta (bcl-x) gene, complete cds /FEA=CDS /DB_XREF=gi:1622940 /UG=Hs.305890 BCL2-like 1 U72398 BCL2-like 1 BCL2L1 598 NM_001191 /// NM_138578 /// XM_005260481 /// XM_005260482 /// XM_005260483 /// XM_005260484 /// XM_005260485 /// XM_005260486 /// XM_005260487 /// XM_006723843 /// XM_006723844 /// XM_006723845 0000910 // cytokinesis // inferred from mutant phenotype /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0019050 // suppression by virus of host apoptotic process // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046898 // response to cycloheximide // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071839 // apoptotic process in bone marrow // inferred from electronic annotation /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred by curator /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // non-traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded /// 0051434 // BH3 domain binding // inferred from physical interaction 215038_s_at AF049103 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF049103.1 /DEF=Homo sapiens Huntingtin interacting protein mRNA, partial cds. /FEA=mRNA /PROD=Huntingtin interacting protein /DB_XREF=gi:3319281 /UG=Hs.306184 Huntingtin interacting protein B AF049103 SET domain containing 2 SETD2 29072 NM_012271 /// NM_014159 /// XM_005265094 /// XM_006713119 /// XM_006713120 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0010452 // histone H3-K36 methylation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018023 // peptidyl-lysine trimethylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034728 // nucleosome organization // inferred from mutant phenotype /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035441 // cell migration involved in vasculogenesis // inferred from electronic annotation /// 0048332 // mesoderm morphogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048864 // stem cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0097198 // histone H3-K36 trimethylation // inferred from direct assay /// 0097198 // histone H3-K36 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046914 // transition metal ion binding // inferred from electronic annotation 215039_at AK002179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002179.1 /DEF=Homo sapiens cDNA FLJ11317 fis, clone PLACE1010261, moderately similar to SEGREGATION DISTORTER PROTEIN. /FEA=mRNA /DB_XREF=gi:7023899 /UG=Hs.306423 Homo sapiens cDNA FLJ11317 fis, clone PLACE1010261, moderately similar to SEGREGATION DISTORTER PROTEIN AK002179 long intergenic non-protein coding RNA 1140 LINC01140 339524 NM_207357 /// NR_026985 /// NR_026986 /// NR_026987 /// NR_026988 /// NR_026989 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 215040_at AL049218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049218.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I1916 (from clone DKFZp564I1916). /FEA=mRNA /DB_XREF=gi:4499947 /UG=Hs.306291 Homo sapiens mRNA; cDNA DKFZp564I1916 (from clone DKFZp564I1916) AL049218 ribonuclease H2, subunit B RNASEH2B 79621 NM_001142279 /// NM_024570 /// XM_005266524 /// XM_005266525 /// XM_006719867 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006401 // RNA catabolic process // inferred from direct assay /// 0009259 // ribonucleotide metabolic process // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000001 // regulation of DNA damage checkpoint // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0032299 // ribonuclease H2 complex // inferred from direct assay 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from electronic annotation 215041_s_at BE259050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE259050 /FEA=EST /DB_XREF=gi:9129548 /DB_XREF=est:601110055F1 /CLONE=IMAGE:3350965 /UG=Hs.307137 Human DNA sequence from clone RP11-155N3 on chromosome 13 Contains ESTs, STSs and GSSs. Contains the 3 part of a novel gene similar to KIAA0694, the KIAA1058 gene and a putative novel gene BE259050 dedicator of cytokinesis 9 DOCK9 23348 NM_001130048 /// NM_001130049 /// NM_001130050 /// NM_015296 /// XM_005254034 /// XM_005254035 /// XM_005254036 /// XM_006719922 /// XM_006719923 /// XM_006719924 /// XM_006719925 /// XM_006719926 /// XM_006719927 /// XM_006719928 /// XM_006719929 /// XM_006719930 /// XM_006719931 /// XM_006719932 /// XM_006719933 /// XM_006719934 /// XM_006719935 /// XM_006719936 /// XM_006719937 /// XM_006719938 /// XM_006719939 /// XM_006719940 /// XM_006719941 /// XM_006719942 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation 215042_at AI123471 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123471 /FEA=EST /DB_XREF=gi:3539237 /DB_XREF=est:ov49h03.x1 /CLONE=IMAGE:1640693 /UG=Hs.6101 hypothetical protein MGC3178 AI123471 bone morphogenetic protein 6 BMP6 654 NM_001718 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001654 // eye development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0003323 // type B pancreatic cell development // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030539 // male genitalia development // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032349 // positive regulation of aldosterone biosynthetic process // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050714 // positive regulation of protein secretion // non-traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 2000105 // positive regulation of DNA-dependent DNA replication // non-traceable author statement /// 2000860 // positive regulation of aldosterone secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from physical interaction 215043_s_at X83301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83301.1 /DEF=H.sapiens SMA5 mRNA. /FEA=mRNA /GEN=SMA5 /DB_XREF=gi:603029 /UG=Hs.324728 SMA5 X83301 glucuronidase, beta pseudogene 3 /// glucuronidase, beta pseudogene /// glucuronidase, beta pseudogene GUSBP3 /// SMA4 /// SMA5 11039 /// 11042 /// 653188 NM_006780 /// NM_021036 /// NM_021652 /// NR_024054 /// NR_027386 /// NR_029426 /// NR_034021 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 215044_s_at AI571996 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI571996 /FEA=EST /DB_XREF=gi:4535370 /DB_XREF=est:tr72c03.x1 /CLONE=IMAGE:2223844 /UG=Hs.306650 Homo sapiens cDNA FLJ13428 fis, clone PLACE1002493, highly similar to Homo sapiens signal transducing adaptor molecule 2A (STAM2) mRNA AI571996 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 STAM2 10254 NM_005843 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215045_at BC004145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004145.1 /DEF=Homo sapiens, clone IMAGE:3509783, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3509783) /DB_XREF=gi:13278737 /UG=Hs.332322 Homo sapiens, clone IMAGE:3509783, mRNA, partial cds BC004145 CUGBP, Elav-like family member 3 CELF3 11189 NM_001172648 /// NM_001172649 /// NM_001291106 /// NM_001291107 /// NM_007185 /// XM_005244858 /// XM_005244859 /// XM_006711139 /// XM_006711140 /// XM_006711141 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0030317 // sperm motility // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from mutant phenotype /// 0003729 // mRNA binding // non-traceable author statement 215046_at AL133053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133053.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H1215 (from clone DKFZp434H1215); partial cds. /FEA=mRNA /GEN=DKFZp434H1215 /PROD=hypothetical protein /DB_XREF=gi:6453471 /UG=Hs.331564 Homo sapiens mRNA; cDNA DKFZp434H1215 (from clone DKFZp434H1215); partial cds AL133053 KAT8 regulatory NSL complex subunit 1-like KANSL1L 151050 NM_152519 /// XM_005246328 /// XM_005246329 /// XM_005246330 /// XM_005246332 /// XM_005246333 /// XM_005246334 /// XM_005246335 /// XM_006712319 /// XM_006712320 0000123 // histone acetyltransferase complex // inferred from electronic annotation 215047_at AL080170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080170.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C091 (from clone DKFZp434C091); partial cds. /FEA=mRNA /GEN=DKFZp434C091 /PROD=hypothetical protein /DB_XREF=gi:5262639 /UG=Hs.51692 DKFZP434C091 protein AL080170 tripartite motif containing 58 TRIM58 25893 NM_015431 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215048_at AW663885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW663885 /FEA=EST /DB_XREF=gi:7456424 /DB_XREF=est:hi73b02.x1 /CLONE=IMAGE:2977899 /UG=Hs.43834 Homo sapiens immunoglobulin lambda gene locus DNA, clone:288A10 AW663885 zinc finger protein 280B ZNF280B 140883 NM_080764 /// XM_005261338 /// XM_006725400 /// XM_006725401 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215049_x_at Z22969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22969.1 /DEF=H.sapiens mRNA for M130 antigen cytoplasmic variant 1. /FEA=mRNA /PROD=M130 antigen cytoplasmic variant 1 /DB_XREF=gi:312143 /UG=Hs.74076 CD163 antigen Z22969 CD163 molecule CD163 9332 NM_004244 /// NM_203416 /// XM_005253528 /// XM_005253529 /// XR_429039 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005044 // scavenger receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215050_x_at BG325734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG325734 /FEA=EST /DB_XREF=gi:13132158 /DB_XREF=est:602424445F1 /CLONE=IMAGE:4562411 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 BG325734 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 /// XM_005273353 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032675 // regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 215051_x_at BF213829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF213829 /FEA=EST /DB_XREF=gi:11107415 /DB_XREF=est:601848003F1 /CLONE=IMAGE:4078849 /UG=Hs.76364 allograft inflammatory factor 1 BF213829 allograft inflammatory factor 1 AIF1 199 NM_001623 /// NM_004847 /// NM_032955 /// XM_005248869 /// XM_005248870 /// XM_005248871 /// XM_005272777 /// XM_005272778 /// XM_005272779 /// XM_005274923 /// XM_005274924 /// XM_005274925 /// XM_005275219 /// XM_005275220 /// XM_005275221 /// XM_005275355 /// XM_005275356 /// XM_005275357 /// XM_005275514 /// XM_005275515 /// XM_005275516 0001774 // microglial cell activation // non-traceable author statement /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006954 // inflammatory response // non-traceable author statement /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030041 // actin filament polymerization // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from sequence or structural similarity /// 0071672 // negative regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0097178 // ruffle assembly // inferred from sequence or structural similarity /// 0097178 // ruffle assembly // non-traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 215052_at AW297087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW297087 /FEA=EST /DB_XREF=gi:6703723 /DB_XREF=est:UI-H-BI2-aie-b-09-0-UI.s1 /CLONE=IMAGE:2729032 /UG=Hs.92025 KIAA0316 gene product AW297087 FERM and PDZ domain containing 4 FRMPD4 9758 NM_014728 /// XM_005274632 /// XM_006724524 0051835 // positive regulation of synapse structural plasticity // inferred from mutant phenotype 0005856 // cytoskeleton // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation 215053_at AK023808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023808.1 /DEF=Homo sapiens cDNA FLJ13746 fis, clone PLACE3000254, moderately similar to Homo sapiens transcriptional activator SRCAP (SRCAP) mRNA. /FEA=mRNA /DB_XREF=gi:10435856 /UG=Hs.87908 Snf2-related CBP activator protein AK023808 Snf2-related CREBBP activator protein SRCAP 10847 NM_006662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215054_at H16758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H16758 /FEA=EST /DB_XREF=gi:882998 /DB_XREF=est:ym34e03.s1 /CLONE=IMAGE:50015 /UG=Hs.89548 erythropoietin receptor H16758 erythropoietin receptor /// ral guanine nucleotide dissociation stimulator-like 3 EPOR /// RGL3 2057 /// 57139 NM_000121 /// NM_001035223 /// NM_001161616 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032315 // regulation of Ral GTPase activity // inferred from electronic annotation /// 0032852 // positive regulation of Ral GTPase activity // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008321 // Ral guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 215055_at U79265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79265.1 /DEF=Human clone 23614 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710224 /UG=Hs.91375 Human clone 23614 mRNA sequence U79265 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 B3GNTL1 146712 NM_001009905 /// XM_006722272 /// XM_006722273 /// XM_006722274 /// XM_006725289 /// XM_006725290 /// XR_243519 /// XR_430780 0008152 // metabolic process // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 215056_at AI267546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI267546 /FEA=EST /DB_XREF=gi:3886713 /DB_XREF=est:aq90f05.x1 /CLONE=IMAGE:2038209 /UG=Hs.90798 Human clone 23695 mRNA sequence AI267546 215057_at U66046 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U66046.1 /DEF=Homo sapiens clone 161455 breast expressed mRNA from chromosome X. /FEA=mRNA /DB_XREF=gi:1519271 /UG=Hs.92683 Homo sapiens clone 161455 breast expressed mRNA from chromosome X U66046 long intergenic non-protein coding RNA 894 LINC00894 100272228 NR_027456 215058_at AU144041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144041 /FEA=EST /DB_XREF=gi:11005562 /DB_XREF=est:AU144041 /CLONE=HEMBA1000726 /UG=Hs.293834 Homo sapiens cDNA FLJ11403 fis, clone HEMBA1000726 AU144041 DENN/MADD domain containing 5B DENND5B 160518 NM_144973 /// XM_005253326 /// XM_005253327 /// XM_005253330 /// XM_006719040 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // not recorded 0016020 // membrane // not recorded /// 0016021 // integral component of membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 215059_at AA053967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA053967 /FEA=EST /DB_XREF=gi:1544893 /DB_XREF=est:ze75h04.s1 /CLONE=IMAGE:364855 /UG=Hs.51515 Homo sapiens mRNA; cDNA DKFZp564G112 (from clone DKFZp564G112) AA053967 215060_at AL390145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390145.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762C115 (from clone DKFZp762C115). /FEA=mRNA /DB_XREF=gi:9368878 /UG=Hs.284330 Homo sapiens mRNA; cDNA DKFZp762C115 (from clone DKFZp762C115) AL390145 215061_at AK023081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023081.1 /DEF=Homo sapiens cDNA FLJ13019 fis, clone NT2RP3000736, highly similar to Human mRNA for KIAA0140 gene. /FEA=mRNA /DB_XREF=gi:10434836 /UG=Hs.279629 Homo sapiens cDNA FLJ13019 fis, clone NT2RP3000736, highly similar to Human mRNA for KIAA0140 gene AK023081 methyltransferase like 10 METTL10 399818 NM_212554 0006400 // tRNA modification // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 215062_at AL390143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390143.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547N074 (from clone DKFZp547N074). /FEA=mRNA /DB_XREF=gi:9368876 /UG=Hs.284257 Homo sapiens mRNA; cDNA DKFZp547N074 (from clone DKFZp547N074) AL390143 215063_x_at AL390149 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390149.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547B026 (from clone DKFZp547B026). /FEA=mRNA /DB_XREF=gi:9368883 /UG=Hs.283862 Homo sapiens mRNA; cDNA DKFZp547B026 (from clone DKFZp547B026) AL390149 leucine rich repeat containing 40 LRRC40 55631 NM_017768 /// XM_005271013 /// XM_006710757 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215064_at AK027246 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027246.1 /DEF=Homo sapiens cDNA: FLJ23593 fis, clone LNG14821. /FEA=mRNA /DB_XREF=gi:10440333 /UG=Hs.287749 Homo sapiens cDNA: FLJ23593 fis, clone LNG14821 AK027246 sterol-C5-desaturase SC5D 6309 NM_001024956 /// NM_006918 0006629 // lipid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033490 // cholesterol biosynthetic process via lathosterol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000248 // C-5 sterol desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050046 // lathosterol oxidase activity // inferred from electronic annotation 215065_at AF091081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF091081.1 /DEF=Homo sapiens clone 617 unknown mRNA, complete sequence. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3859999 /UG=Hs.285641 KIAA1111 protein AF091081 PHD finger protein 8 PHF8 23133 NM_001184896 /// NM_001184897 /// NM_001184898 /// NM_015107 /// XM_005261996 /// XM_005261997 /// XM_005261998 /// XM_005261999 /// XM_005262000 /// XM_006724585 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0035574 // histone H4-K20 demethylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061188 // negative regulation of chromatin silencing at rDNA // inferred from direct assay /// 0070544 // histone H3-K36 demethylation // inferred from direct assay /// 0071557 // histone H3-K27 demethylation // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from direct assay /// 0032452 // histone demethylase activity // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0035575 // histone demethylase activity (H4-K20 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from direct assay 215066_at AU158443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158443 /FEA=EST /DB_XREF=gi:11019964 /DB_XREF=est:AU158443 /CLONE=PLACE2000398 /UG=Hs.287592 Homo sapiens cDNA FLJ13713 fis, clone PLACE2000398, moderately similar to LAR PROTEIN PRECURSOR (LEUKOCYTE ANTIGEN RELATED) (EC 3.1.3.48) AU158443 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 215067_x_at AU147942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147942 /FEA=EST /DB_XREF=gi:11009463 /DB_XREF=est:AU147942 /CLONE=MAMMA1002198 /UG=Hs.287517 Homo sapiens cDNA FLJ12333 fis, clone MAMMA1002198, highly similar to THIOREDOXIN PEROXIDASE 1 AU147942 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181737 /// NM_181738 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 215068_s_at BC004228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004228.1 /DEF=Homo sapiens, clone IMAGE:3543931, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3543931) /DB_XREF=gi:13278953 /UG=Hs.287418 hypothetical protein FLJ11467 BC004228 F-box and leucine-rich repeat protein 18 FBXL18 80028 NM_024963 /// XM_005249853 /// XM_005249854 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215069_at AK025065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025065.1 /DEF=Homo sapiens cDNA: FLJ21412 fis, clone COL03987. /FEA=mRNA /DB_XREF=gi:10437504 /UG=Hs.288066 Homo sapiens cDNA: FLJ21412 fis, clone COL03987 AK025065 N-myristoyltransferase 2 NMT2 9397 NM_004808 /// XM_005252642 /// XM_005252643 /// XM_006717539 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215070_x_at AK022408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022408.1 /DEF=Homo sapiens cDNA FLJ12346 fis, clone MAMMA1002297, highly similar to Homo sapiens mRNA for Rab6 GTPase activating protein. /FEA=mRNA /DB_XREF=gi:10433799 /UG=Hs.288915 Homo sapiens cDNA FLJ12346 fis, clone MAMMA1002297, highly similar to Homo sapiens mRNA for Rab6 GTPase activating protein AK022408 RAB GTPase activating protein 1 RABGAP1 23637 NM_012197 /// XM_005251866 /// XM_005251868 /// XM_006717031 /// XM_006717032 0007049 // cell cycle // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // traceable author statement 215071_s_at AL353759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353759 /DEF=Human DNA sequence from clone RP1-221C16 on chromosome 6. Contains two genes for novel histone 4 family members, two genes for novel histone 1 family members, three genes for novel histone 2B family members, a gene for a novel histone 2A family me... /FEA=mRNA_18 /DB_XREF=gi:8745068 /UG=Hs.28777 H2A histone family, member L AL353759 histone cluster 1, H2ac HIST1H2AC 8334 NM_003512 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215072_x_at AK025270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025270.1 /DEF=Homo sapiens cDNA: FLJ21617 fis, clone COL07481. /FEA=mRNA /DB_XREF=gi:10437751 /UG=Hs.288802 hypothetical protein FLJ21617 AK025270 erythroid differentiation regulatory factor 1 EDRF1 26098 NM_001202438 /// NM_015608 /// NM_030897 /// NR_110857 /// NR_110858 /// NR_110859 /// XM_005269687 /// XM_005269688 /// XM_005269689 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 215073_s_at AL554245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL554245 /FEA=EST /DB_XREF=gi:12894837 /DB_XREF=est:AL554245 /CLONE=CS0DI082YA02 (5 prime) /UG=Hs.288869 nuclear receptor subfamily 2, group F, member 2 AL554245 nuclear receptor subfamily 2, group F, member 2 NR2F2 7026 NM_001145155 /// NM_001145156 /// NM_001145157 /// NM_021005 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009956 // radial pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060849 // regulation of transcription involved in lymphatic endothelial cell fate commitment // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215074_at AK022489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022489.1 /DEF=Homo sapiens cDNA FLJ12427 fis, clone MAMMA1003127, highly similar to MYOSIN I ALPHA. /FEA=mRNA /DB_XREF=gi:10433902 /UG=Hs.301289 Homo sapiens cDNA FLJ12427 fis, clone MAMMA1003127, highly similar to MYOSIN I ALPHA AK022489 myosin IB MYO1B 4430 NM_001130158 /// NM_001161819 /// NM_012223 /// XM_005246569 /// XM_005246572 /// XM_005246575 /// XM_005246577 /// XM_006712536 /// XM_006712537 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005769 // early endosome // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005903 // brush border // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from sequence or structural similarity 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000146 // microfilament motor activity // inferred from sequence or structural similarity /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from mutant phenotype 215075_s_at L29511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L29511.1 /DEF=Human GRB2 isoform mRNA. /FEA=mRNA /PROD=growth factor receptor-bound protein 3 /DB_XREF=gi:460667 /UG=Hs.296381 growth factor receptor-bound protein 2 L29511 growth factor receptor-bound protein 2 GRB2 2885 NM_002086 /// NM_203506 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070436 // Grb2-EGFR complex // inferred from direct assay 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation 215076_s_at AU144167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144167 /FEA=EST /DB_XREF=gi:11005688 /DB_XREF=est:AU144167 /CLONE=HEMBA1001071 /UG=Hs.297909 Homo sapiens cDNA FLJ11428 fis, clone HEMBA1001071, highly similar to PROCOLLAGEN ALPHA 1(III) CHAIN PRECURSOR AU144167 collagen, type III, alpha 1 COL3A1 1281 NM_000090 0001501 // skeletal system development // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // non-traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005586 // collagen type III trimer // inferred from mutant phenotype /// 0005586 // collagen type III trimer // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement 0005178 // integrin binding // inferred from mutant phenotype /// 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 215077_at AU144167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144167 /FEA=EST /DB_XREF=gi:11005688 /DB_XREF=est:AU144167 /CLONE=HEMBA1001071 /UG=Hs.297909 Homo sapiens cDNA FLJ11428 fis, clone HEMBA1001071, highly similar to PROCOLLAGEN ALPHA 1(III) CHAIN PRECURSOR AU144167 215078_at AL050388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050388.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M2422 (from clone DKFZp564M2422); partial cds. /FEA=mRNA /GEN=DKFZp564M2422 /PROD=hypothetical protein /DB_XREF=gi:4914612 /UG=Hs.306320 Homo sapiens mRNA; cDNA DKFZp564M2422 (from clone DKFZp564M2422); partial cds AL050388 uncharacterized LOC100129518 /// superoxide dismutase 2, mitochondrial LOC100129518 /// SOD2 6648 /// 100129518 NM_000636 /// NM_001024465 /// NM_001024466 /// NR_037166 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from mutant phenotype /// 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001315 // age-dependent response to reactive oxygen species // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0003032 // detection of oxygen // inferred from electronic annotation /// 0003069 // vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034021 // response to silicon dioxide // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048773 // erythrophore differentiation // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0030145 // manganese ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215079_at AK026723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026723.1 /DEF=Homo sapiens cDNA: FLJ23070 fis, clone LNG05629. /FEA=mRNA /DB_XREF=gi:10439641 /UG=Hs.30579 Homo sapiens cDNA: FLJ23070 fis, clone LNG05629 AK026723 215080_s_at U81031 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U81031 /DEF=Homo sapiens cosmid 6E5 CDK4, SAS and KIAA0167 genes, complete cds, and OS9 gene, partial cds /FEA=CDS_1 /DB_XREF=gi:2209289 /UG=Hs.302435 phosphoinositide 3-kinase enhancer U81031 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 AGAP2 116986 NM_001122772 /// NM_014770 /// XM_005268625 /// XM_005268626 /// XR_245891 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215081_at AF035294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035294.1 /DEF=Homo sapiens clone 23597 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661049 /UG=Hs.301654 KIAA1024 protein AF035294 KIAA1024 KIAA1024 23251 NM_015206 /// XM_006720441 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215082_at BF973387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF973387 /FEA=EST /DB_XREF=gi:12340602 /DB_XREF=est:602242353F1 /CLONE=IMAGE:4330861 /UG=Hs.305989 Human DNA sequence from clone RP3-483K16 on chromosome 6p12.1-21.1. Contains (parts of) two novel genes, RPS16 (40S Ribosomal protein S16) and RPL31 (60S Ribosomal protein L31) pseudogenes, ESTs, STSs, GSSs and four putative CpG islands BF973387 ELOVL fatty acid elongase 5 ELOVL5 60481 NM_001242828 /// NM_001242830 /// NM_001242831 /// NM_021814 /// XM_005249266 /// XM_005249267 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034625 // fatty acid elongation, monounsaturated fatty acid // inferred from direct assay /// 0034626 // fatty acid elongation, polyunsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 215083_at AL049263 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049263.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F133 (from clone DKFZp564F133). /FEA=mRNA /DB_XREF=gi:4500011 /UG=Hs.306292 Homo sapiens mRNA; cDNA DKFZp564F133 (from clone DKFZp564F133) AL049263 215084_s_at AL031427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031427 /DEF=Human DNA sequence from clone 167A19 on chromosome 1p32.1-33. Contains three genes for novel proteins, the DIO1 gene for type I iodothyronine deiodinase (EC 3.8.1.4, TXDI1, ITDI1) and an HNRNP A3 (Heterogenous Nuclear Ribonucleoprotein A3, FBRNP) ... /FEA=mRNA_2 /DB_XREF=gi:4835258 /UG=Hs.40094 Human DNA sequence from clone 167A19 on chromosome 1p32.1-33. Contains three genes for novel proteins, the DIO1 gene for type I iodothyronine deiodinase (EC 3.8.1.4, TXDI1, ITDI1) and an HNRNP A3 (Heterogenous Nuclear Ribonucleoprotein A3, FBRNP) pseudoge AL031427 leucine rich repeat containing 42 LRRC42 115353 NM_001256409 /// NM_052940 /// XM_006710327 /// XM_006710328 215085_x_at AL137706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137706.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A2322 (from clone DKFZp434A2322). /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:6808070 /UG=Hs.306464 Homo sapiens mRNA; cDNA DKFZp434A2322 (from clone DKFZp434A2322) AL137706 deleted in lung and esophageal cancer 1 DLEC1 9940 NM_007335 /// NM_007336 /// NM_007337 /// NM_007338 /// XM_005265630 /// XM_005265631 /// XM_006713437 /// XM_006713438 /// XM_006713439 /// XM_006713440 /// XM_006713441 /// XR_427301 /// XR_427302 0008285 // negative regulation of cell proliferation // traceable author statement 0005737 // cytoplasm // inferred from direct assay 215086_at AB037838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037838.1 /DEF=Homo sapiens mRNA for KIAA1417 protein, partial cds. /FEA=mRNA /GEN=KIAA1417 /PROD=KIAA1417 protein /DB_XREF=gi:7243214 /UG=Hs.306425 Homo sapiens mRNA for KIAA1417 protein, partial cds AB037838 inhibitor of Bruton agammaglobulinemia tyrosine kinase IBTK 25998 NM_015525 /// XM_006715453 /// XM_006715454 /// XM_006715455 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay 215087_at AL109730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109730.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 68600. /FEA=mRNA /DB_XREF=gi:5689835 /UG=Hs.306331 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 68600 AL109730 chromosome 15 open reading frame 39 C15orf39 56905 NM_015492 /// XM_005254551 /// XM_006720613 0005737 // cytoplasm // inferred from direct assay 215088_s_at BG110532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG110532 /FEA=EST /DB_XREF=gi:12604038 /DB_XREF=est:602278961F1 /CLONE=IMAGE:4366575 /UG=Hs.3577 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD BG110532 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa SDHC 6391 NM_001035511 /// NM_001035512 /// NM_001035513 /// NM_001278172 /// NM_003001 /// NR_103459 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0045273 // respiratory chain complex II // traceable author statement /// 0045281 // succinate dehydrogenase complex // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215089_s_at AW409974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW409974 /FEA=EST /DB_XREF=gi:6935515 /DB_XREF=est:fh03d12.y1 /CLONE=IMAGE:2961094 /UG=Hs.332750 Homo sapiens cDNA FLJ10100 fis, clone HEMBA1002469, moderately similar to DXS8237E PROTEIN AW409974 RNA binding motif protein 10 RBM10 8241 NM_001204466 /// NM_001204467 /// NM_001204468 /// NM_005676 /// NM_152856 /// XM_005272677 /// XM_005272678 /// XM_005272679 /// XM_006724563 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0034391 // regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215090_x_at AK021884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021884.1 /DEF=Homo sapiens cDNA FLJ11822 fis, clone HEMBA1006485, highly similar to PUROMYCIN-SENSITIVE AMINOPEPTIDASE (EC 3.4.11.-). /FEA=mRNA /DB_XREF=gi:10433170 /UG=Hs.326350 Homo sapiens cDNA FLJ11822 fis, clone HEMBA1006485, highly similar to PUROMYCIN-SENSITIVE AMINOPEPTIDASE (EC 3.4.11.-) AK021884 aminopeptidase puromycin sensitive pseudogene LOC440434 440434 NR_036750 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215091_s_at BE542815 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE542815 /FEA=EST /DB_XREF=gi:9771460 /DB_XREF=est:601067630F1 /CLONE=IMAGE:3453846 /UG=Hs.75113 general transcription factor IIIA BE542815 general transcription factor IIIA GTF3A 2971 NM_002097 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215092_s_at AJ005683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ005683.1 /DEF=Homo sapiens mRNA for repeated sequence CAG-8-man-kl. /FEA=mRNA /DB_XREF=gi:6900107 /UG=Hs.86998 nuclear factor of activated T-cells 5, tonicity-responsive AJ005683 nuclear factor of activated T-cells 5, tonicity-responsive NFAT5 10725 NM_001113178 /// NM_006599 /// NM_138713 /// NM_138714 /// NM_173214 /// NM_173215 /// XM_005255777 /// XM_006721125 0001816 // cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007588 // excretion // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0070884 // regulation of calcineurin-NFAT signaling cascade // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215093_at U82671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82671 /DEF=Homo sapiens chromosome Xq28 melanoma antigen family A2a (MAGEA2A), melanoma antigen family A12 (MAGEA12), melanoma antigen family A2b (MAGEA2B), melanoma antigen family A3 (MAGEA3), caltractin (CALT), NAD(P)H dehydrogenase-like protein (NSDHL), a... /FEA=mRNA_9 /DB_XREF=gi:7280331 /UG=Hs.57698 NAD(P) dependent steroid dehydrogenase-like; H105e3 U82671 NAD(P) dependent steroid dehydrogenase-like NSDHL 50814 NM_001129765 /// NM_015922 /// XM_006724824 0001942 // hair follicle development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047012 // sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 215094_at U79249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79249.1 /DEF=Human clone 23839 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710196 /UG=Hs.78362 Human clone 23839 mRNA sequence U79249 spindle and centriole associated protein 1 SPICE1 152185 NM_144718 /// XM_006713515 /// XR_241469 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051310 // metaphase plate congression // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 215095_at AU145746 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145746 /FEA=EST /DB_XREF=gi:11007267 /DB_XREF=est:AU145746 /CLONE=HEMBA1005679 /UG=Hs.82193 esterase Dformylglutathione hydrolase AU145746 215096_s_at AU145746 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145746 /FEA=EST /DB_XREF=gi:11007267 /DB_XREF=est:AU145746 /CLONE=HEMBA1005679 /UG=Hs.82193 esterase Dformylglutathione hydrolase AU145746 esterase D ESD 2098 NM_001984 /// XM_005266278 0006508 // proteolysis // inferred from electronic annotation /// 0046294 // formaldehyde catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from direct assay /// 0018738 // S-formylglutathione hydrolase activity // inferred from electronic annotation /// 0047374 // methylumbelliferyl-acetate deacetylase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // non-traceable author statement 215097_at BG420053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG420053 /FEA=EST /DB_XREF=gi:13326559 /DB_XREF=est:602453740F1 /CLONE=IMAGE:4592120 /UG=Hs.76368 capping protein (actin filament) muscle Z-line, beta BG420053 capping protein (actin filament) muscle Z-line, beta CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 215098_at BF337038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF337038 /FEA=EST /DB_XREF=gi:11283134 /DB_XREF=est:602034430F1 /CLONE=IMAGE:4182654 /UG=Hs.79372 retinoid X receptor, beta BF337038 retinoid X receptor, beta RXRB 6257 NM_001270401 /// NM_001291989 /// NM_021976 /// XM_005249278 /// XM_005249279 /// XM_005272854 /// XM_005272855 /// XM_005275007 /// XM_005275008 /// XM_005275149 /// XM_005275150 /// XM_005275276 /// XM_005275277 /// XM_005275438 /// XM_005275439 /// XM_006715162 /// XM_006725494 /// XM_006725708 /// XM_006725825 /// XM_006725917 /// XM_006726010 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215099_s_at BF337038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF337038 /FEA=EST /DB_XREF=gi:11283134 /DB_XREF=est:602034430F1 /CLONE=IMAGE:4182654 /UG=Hs.79372 retinoid X receptor, beta BF337038 retinoid X receptor, beta RXRB 6257 NM_001270401 /// NM_001291989 /// NM_021976 /// XM_005249278 /// XM_005249279 /// XM_005272854 /// XM_005272855 /// XM_005275007 /// XM_005275008 /// XM_005275149 /// XM_005275150 /// XM_005275276 /// XM_005275277 /// XM_005275438 /// XM_005275439 /// XM_006715162 /// XM_006725494 /// XM_006725708 /// XM_006725825 /// XM_006725917 /// XM_006726010 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215100_at AL022724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022724 /DEF=Human DNA sequence from clone 413H6 on chromosome 6p22.3-24.3. Contains a hamster Androgen-dependent Expressed Protein like protein gene, ESTs and GSSs /FEA=mRNA /DB_XREF=gi:4468306 /UG=Hs.97411 Human DNA sequence from clone 413H6 on chromosome 6p22.3-24.3. Contains a hamster Androgen-dependent Expressed Protein like protein gene, ESTs and GSSs AL022724 androgen-dependent TFPI-regulating protein ADTRP 84830 NM_001143948 /// NM_032744 /// XM_005249454 /// XM_005249455 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215101_s_at BG166705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG166705 /FEA=EST /DB_XREF=gi:12673408 /DB_XREF=est:602339217F1 /CLONE=IMAGE:4447013 /UG=Hs.89714 small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) BG166705 chemokine (C-X-C motif) ligand 5 CXCL5 6374 NM_002994 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 215102_at AK026768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026768.1 /DEF=Homo sapiens cDNA: FLJ23115 fis, clone LNG07933. /FEA=mRNA /DB_XREF=gi:10439696 /UG=Hs.98728 Homo sapiens cDNA: FLJ23115 fis, clone LNG07933 AK026768 DPY19L1 pseudogene 1 DPY19L1P1 100129460 NR_036680 215103_at AW192911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW192911 /FEA=EST /DB_XREF=gi:6471610 /DB_XREF=est:xl55c12.x1 /CLONE=IMAGE:2678614 /UG=Hs.702 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18 AW192911 cytochrome P450, family 2, subfamily C, polypeptide 18 CYP2C18 1562 NM_000772 /// NM_001128925 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 215104_at AL136557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136557.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G1913 (from clone DKFZp761G1913). /FEA=mRNA /GEN=DKFZp761G1913 /PROD=hypothetical protein /DB_XREF=gi:13276620 /UG=Hs.245880 Homo sapiens mRNA; cDNA DKFZp761G1913 (from clone DKFZp761G1913) AL136557 nuclear receptor interacting protein 2 NRIP2 83714 NM_031474 /// XM_005253796 /// XM_005253797 /// XM_005253798 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215105_at U50531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U50531.1 /DEF=Human BRCA2 region, mRNA sequence CG030. /FEA=mRNA /DB_XREF=gi:1531602 /UG=Hs.138751 Human BRCA2 region, mRNA sequence CG030 U50531 N4BPL2 intronic transcript 2 (non-protein coding) N4BP2L2-IT2 116828 NR_026928 215106_at AI923972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI923972 /FEA=EST /DB_XREF=gi:5659936 /DB_XREF=est:wn49c10.x1 /CLONE=IMAGE:2448786 /UG=Hs.127723 Homo sapiens mRNA; cDNA DKFZp586J211 (from clone DKFZp586J211) AI923972 tetratricopeptide repeat domain 22 TTC22 55001 NM_001114108 /// NM_017904 215107_s_at AI923972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI923972 /FEA=EST /DB_XREF=gi:5659936 /DB_XREF=est:wn49c10.x1 /CLONE=IMAGE:2448786 /UG=Hs.127723 Homo sapiens mRNA; cDNA DKFZp586J211 (from clone DKFZp586J211) AI923972 tetratricopeptide repeat domain 22 TTC22 55001 NM_001114108 /// NM_017904 215108_x_at U80736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80736.1 /DEF=Homo sapiens CAGF9 mRNA, partial cds. /FEA=mRNA /GEN=CAGF9 /PROD=CAGF9 /DB_XREF=gi:2565047 /UG=Hs.110826 trinucleotide repeat containing 9 U80736 TOX high mobility group box family member 3 TOX3 27324 NM_001080430 /// NM_001146188 /// XM_005255892 /// XM_005255893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0034056 // estrogen response element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 215109_at R02172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R02172 /FEA=EST /DB_XREF=gi:751908 /DB_XREF=est:ye87e07.s1 /CLONE=IMAGE:124740 /UG=Hs.127338 KIAA0492 protein R02172 ring finger and CCCH-type domains 1 RC3H1 149041 NM_172071 /// XM_005244918 /// XM_005244919 /// XM_005244920 /// XM_005244921 /// XM_006711183 0000956 // nuclear-transcribed mRNA catabolic process // inferred from sequence or structural similarity /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002635 // negative regulation of germinal center formation // inferred from sequence or structural similarity /// 0010608 // posttranscriptional regulation of gene expression // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from sequence or structural similarity /// 0045623 // negative regulation of T-helper cell differentiation // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0050856 // regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215110_at AF019382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF019382.1 /DEF=Homo sapiens mannose-binding protein-A pseudogene (MBL1P1) mRNA sequence. /FEA=mRNA /GEN=MBL1P1 /DB_XREF=gi:3015577 /UG=Hs.116218 mannose-binding lectin (protein A) 1, pseudogene 1 AF019382 BMS1 homolog, ribosome assembly protein (yeast) pseudogene /// mannose-binding lectin (protein A) 1, pseudogene LOC100288974 /// MBL1P 8512 /// 100288974 NR_002724 /// NR_033857 215111_s_at AK027071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027071.1 /DEF=Homo sapiens cDNA: FLJ23418 fis, clone HEP21245, highly similar to HSU35048 Human TSC-22 protein mRNA. /FEA=mRNA /DB_XREF=gi:10440100 /UG=Hs.114360 transforming growth factor beta-stimulated protein TSC-22 AK027071 TSC22 domain family, member 1 TSC22D1 8848 NM_001243797 /// NM_001243798 /// NM_001243799 /// NM_006022 /// NM_183422 /// XM_005266582 /// XM_005266583 /// XM_006719887 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215112_x_at AB020668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020668.1 /DEF=Homo sapiens mRNA for KIAA0861 protein, partial cds. /FEA=mRNA /GEN=KIAA0861 /PROD=KIAA0861 protein /DB_XREF=gi:4240210 /UG=Hs.126565 KIAA0861 protein AB020668 MCF.2 cell line derived transforming sequence-like 2 MCF2L2 23101 NM_015078 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 215113_s_at AK000923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000923.1 /DEF=Homo sapiens cDNA FLJ10061 fis, clone HEMBA1001413. /FEA=mRNA /DB_XREF=gi:7021892 /UG=Hs.118926 sentrinSUMO-specific protease 3 AK000923 SUMO1/sentrin/SMT3 specific peptidase 3 /// SENP3-EIF4A1 readthrough (NMD candidate) SENP3 /// SENP3-EIF4A1 26168 /// 100533955 NM_015670 /// NR_037926 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215114_at AK000923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000923.1 /DEF=Homo sapiens cDNA FLJ10061 fis, clone HEMBA1001413. /FEA=mRNA /DB_XREF=gi:7021892 /UG=Hs.118926 sentrinSUMO-specific protease 3 AK000923 SUMO1/sentrin/SMT3 specific peptidase 3 SENP3 26168 NM_015670 0006508 // proteolysis // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215115_x_at AI613045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI613045 /FEA=EST /DB_XREF=gi:4622212 /DB_XREF=est:ty68g03.x1 /CLONE=IMAGE:2284276 /UG=Hs.169081 ets variant gene 6 (TEL oncogene) AI613045 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 215116_s_at AF035321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035321.1 /DEF=Homo sapiens clone 23944 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661086 /UG=Hs.166161 dynamin 1 AF035321 dynamin 1 DNM1 1759 NM_001005336 /// NM_001288737 /// NM_001288738 /// NM_001288739 /// NM_004408 /// XM_005251763 /// XM_005251764 /// XM_005251768 /// XM_005251769 /// XM_006716992 /// XM_006716993 /// XM_006716994 /// XR_242572 /// XR_242573 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007032 // endosome organization // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215117_at AW058148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW058148 /FEA=EST /DB_XREF=gi:5933787 /DB_XREF=est:wv81h03.x1 /CLONE=IMAGE:2535989 /UG=Hs.159376 recombination activating gene 2 AW058148 recombination activating gene 2 RAG2 5897 NM_000536 /// NM_001243785 /// NM_001243786 /// NR_033666 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002331 // pre-B cell allelic exclusion // inferred from sequence or structural similarity /// 0002358 // B cell homeostatic proliferation // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0016445 // somatic diversification of immunoglobulins // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0046622 // positive regulation of organ growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0004519 // endonuclease activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from sequence or structural similarity /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from sequence or structural similarity 215118_s_at AW519168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW519168 /FEA=EST /DB_XREF=gi:7157250 /DB_XREF=est:ha52a08.x1 /CLONE=IMAGE:2877302 /UG=Hs.163271 Human alpha-1 Ig germline C-region membrane-coding region, 3 end AW519168 /// Ig alpha 1- alpha 2m=immunoglobulin A1-A2 lambda hybrid GAU heavy chain {membrane exon} [human, myeloma, mRNA Partial, 360 nt]. /// immunoglobulin heavy locus AL928768.3 /// Ig alpha 1-[alpha]2m /// IGH 3492 0001895 // retina homeostasis // inferred from expression pattern /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0003823 // antigen binding // non-traceable author statement /// 0034987 // immunoglobulin receptor binding // inferred from direct assay 215119_at AI522028 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI522028 /FEA=EST /DB_XREF=gi:4436163 /DB_XREF=est:ti85d01.x1 /CLONE=IMAGE:2138785 /UG=Hs.175411 KIAA0865 protein AI522028 myosin XVI MYO16 23026 NM_001198950 /// NM_015011 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity 215120_s_at BF697247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF697247 /FEA=EST /DB_XREF=gi:11982655 /DB_XREF=est:602129775F1 /CLONE=IMAGE:4286586 /UG=Hs.173571 KIAA1053 protein BF697247 sterile alpha motif domain containing 4A SAMD4A 23034 NM_001161576 /// NM_001161577 /// NM_015589 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030371 // translation repressor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 215121_x_at AA680302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA680302 /FEA=EST /DB_XREF=gi:2656270 /DB_XREF=est:ac83d05.s1 /CLONE=IMAGE:869193 /UG=Hs.181125 immunoglobulin lambda locus AA680302 immunoglobulin lambda light chain-like /// immunoglobulin lambda constant 1 (Mcg marker) /// immunoglobulin lambda variable 1-44 CYAT1 /// IGLC1 /// IGLV1-44 3537 /// 28823 /// 100290481 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215122_at AK022330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022330.1 /DEF=Homo sapiens cDNA FLJ12268 fis, clone MAMMA1001627, highly similar to Homo sapiens mRNA for transcription factor TBX6. /FEA=mRNA /DB_XREF=gi:10433704 /UG=Hs.198301 T-box 6 AK022330 T-box 6 TBX6 6911 NM_004608 /// NM_080758 /// XM_005255523 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 215123_at AL049250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049250.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D113 (from clone DKFZp564D113). /FEA=mRNA /DB_XREF=gi:4499989 /UG=Hs.194637 BANP homolog, SMAR1 homolog AL049250 nuclear pore complex-interacting protein family member B4-like /// nuclear pore complex interacting protein pseudogene /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member B3 /// nuclear pore complex interacting protein family, member B4 /// nuclear pore complex interacting protein family, member B5 LOC101929910 /// LOC613037 /// NPIPA5 /// NPIPB3 /// NPIPB4 /// NPIPB5 23117 /// 440345 /// 613037 /// 100132247 /// 100288332 /// 101929910 NM_001135865 /// NM_001277325 /// NM_130464 /// NR_002555 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006721108 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006726610 /// XR_433240 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215124_at BE886287 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE886287 /FEA=EST /DB_XREF=gi:10340242 /DB_XREF=est:601509871F1 /CLONE=IMAGE:3911608 /UG=Hs.249219 Homo sapiens chromosome 19, overlapping cosmids F18547, F11133, R27945, R28830 and R32804 BE886287 zinc finger protein 550 ZNF550 162972 NM_001039654 /// NM_001277090 /// NM_001277091 /// NM_001277092 /// NM_001277093 /// NM_153231 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // /// 0046872 // metal ion binding // inferred from electronic annotation 215125_s_at AV691323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV691323 /FEA=EST /DB_XREF=gi:10293186 /DB_XREF=est:AV691323 /CLONE=GKCEWF11 /UG=Hs.2056 UDP glycosyltransferase 1 family, polypeptide A9 AV691323 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A10 /// UDP glucuronosyltransferase 1 family, polypeptide A3 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A5 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A7 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A10 /// UGT1A3 /// UGT1A4 /// UGT1A5 /// UGT1A6 /// UGT1A7 /// UGT1A8 /// UGT1A9 54575 /// 54576 /// 54577 /// 54578 /// 54579 /// 54600 /// 54657 /// 54658 /// 54659 NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_019077 /// NM_019078 /// NM_019093 /// NM_021027 /// NM_205862 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0051552 // flavone metabolic process // inferred by curator /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0001972 // retinoic acid binding // inferred by curator /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008144 // drug binding // inferred from direct assay /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred by curator /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 215126_at AL109716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109716.2 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 208948. /FEA=mRNA /DB_XREF=gi:9187597 /UG=Hs.20034 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 208948 AL109716 long intergenic non-protein coding RNA 1314 LINC01314 100996492 NR_120317 /// XR_243192 /// XR_248146 /// XR_253417 /// XR_424651 /// XR_429574 /// XR_433141 215127_s_at AL517946 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL517946 /FEA=EST /DB_XREF=gi:12781439 /DB_XREF=est:AL517946 /CLONE=CS0DA004YB11 (3 prime) /UG=Hs.241567 RNA binding motif, single stranded interacting protein 1 AL517946 RNA binding motif, single stranded interacting protein 1 RBMS1 5937 NM_002897 /// NM_016836 /// NM_016839 /// XM_005246737 /// XM_005246738 /// XM_005246739 /// XM_005246740 /// XM_005246741 /// XM_006712671 /// XM_006712672 /// XM_006712673 /// XM_006712674 /// XM_006712675 0006260 // DNA replication // non-traceable author statement /// 0006396 // RNA processing // traceable author statement 0005634 // nucleus // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215128_at AV704232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV704232 /FEA=EST /DB_XREF=gi:10721550 /DB_XREF=est:AV704232 /CLONE=ADBBLB11 /UG=Hs.228096 Homo sapiens cDNA FLJ11682 fis, clone HEMBA1004880 AV704232 215129_at AJ000008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ000008.1 /DEF=Homo sapiens mRNA for C2 domain containing PI3-kinase. /FEA=mRNA /PROD=PI3-kinase /DB_XREF=gi:3288456 /UG=Hs.22500 phosphoinositide-3-kinase, class 2, gamma polypeptide AJ000008 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma PIK3C2G 5288 NM_001288772 /// NM_001288774 /// NM_004570 /// XM_005253393 /// XM_006719088 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // non-traceable author statement /// 0016307 // phosphatidylinositol phosphate kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 215130_s_at AC002550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002550 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-101F10 /FEA=CDS_1 /DB_XREF=gi:2570261 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B AC002550 IQ motif containing K IQCK 124152 NM_153208 /// XM_006721019 /// XR_243261 215131_at AC002550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002550 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-101F10 /FEA=CDS_1 /DB_XREF=gi:2570261 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B AC002550 IQ motif containing K IQCK 124152 NM_153208 /// XM_006721019 /// XR_243261 215132_at AL137474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137474.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E2423 (from clone DKFZp434E2423). /FEA=mRNA /DB_XREF=gi:6808085 /UG=Hs.244772 Homo sapiens mRNA; cDNA DKFZp434E2423 (from clone DKFZp434E2423) AL137474 215133_s_at AL117630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117630.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D115 (from clone DKFZp434D115). /FEA=mRNA /DB_XREF=gi:5912213 /UG=Hs.252723 ribosomal protein L19 AL117630 family with sequence similarity 153, member A /// family with sequence similarity 153, member B /// uncharacterized LOC100507387 /// uncharacterized LOC102725213 FAM153A /// FAM153B /// LOC100507387 /// LOC102725213 202134 /// 285596 /// 100507387 /// 102725213 NM_001079529 /// NM_001265615 /// NM_173663 /// NR_038402 /// XM_005265889 /// XM_006714841 /// XM_006714842 /// XM_006714843 /// XM_006714844 /// XM_006714845 /// XM_006714846 /// XM_006714847 /// XM_006714848 /// XM_006714849 /// XM_006714850 /// XM_006714851 /// XM_006714852 /// XM_006714853 /// XM_006714854 /// XR_425938 /// XR_425939 /// XR_431945 /// XR_431946 /// XR_431947 215134_at H84390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H84390 /FEA=EST /DB_XREF=gi:1063061 /DB_XREF=est:yv85g11.r1 /CLONE=IMAGE:249572 /UG=Hs.25300 phosphatidylinositol 4-kinase type II H84390 phosphatidylinositol 4-kinase type 2 alpha PI4K2A 55361 NM_018425 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0035838 // growing cell tip // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044231 // host cell presynaptic membrane // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004430 // 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035651 // AP-3 adaptor complex binding // inferred from direct assay 215135_at AI690583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI690583 /FEA=EST /DB_XREF=gi:4901885 /DB_XREF=est:tq02b05.x1 /CLONE=IMAGE:2207601 /UG=Hs.258551 aspartyl aminopeptidase AI690583 aspartyl aminopeptidase DNPEP 23549 NM_012100 /// XM_005246430 /// XM_005246431 /// XM_005246432 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215136_s_at AL050353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050353.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C0482 (from clone DKFZp564C0482). /FEA=mRNA /DB_XREF=gi:4914574 /UG=Hs.274170 Opa-interacting protein 2 AL050353 exosome component 8 EXOSC8 11340 NM_181503 /// XM_006719763 /// XR_429212 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay 215137_at H92070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H92070 /FEA=EST /DB_XREF=gi:1087648 /DB_XREF=est:ys84f02.s1 /CLONE=IMAGE:221499 /UG=Hs.270010 KIAA0508 protein H92070 215138_s_at AB015329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB015329.1 /DEF=Homo sapiens HRIHFB2003 mRNA, partial cds. /FEA=mRNA /GEN=HRIHFB2003 /DB_XREF=gi:6526768 /UG=Hs.27742 KIAA1026 protein AB015329 kazrin, periplakin interacting protein KAZN 23254 NM_001017999 /// NM_001018000 /// NM_001018001 /// NM_015209 /// NM_201628 /// XM_005245795 /// XM_005245796 0031424 // keratinization // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215139_at AL137508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137508.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761P221 (from clone DKFZp761P221). /FEA=mRNA /DB_XREF=gi:6808163 /UG=Hs.224403 Homo sapiens mRNA; cDNA DKFZp761P221 (from clone DKFZp761P221) AL137508 Rho guanine nucleotide exchange factor (GEF) 10 ARHGEF10 9639 NM_014629 /// XM_005266039 /// XM_005266040 /// XM_005266041 /// XM_005266042 /// XM_006716238 /// XM_006716239 /// XM_006716240 /// XM_006716241 /// XM_006725104 /// XM_006725105 /// XM_006725106 /// XM_006725107 /// XM_006725108 /// XM_006725109 /// XM_006725110 /// XM_006725111 0022011 // myelination in peripheral nervous system // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0033126 // positive regulation of GTP catabolic process // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction 215140_at AL109667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109667.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 381867. /FEA=mRNA /DB_XREF=gi:5689815 /UG=Hs.124154 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 381867 AL109667 215141_at AA493300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA493300 /FEA=EST /DB_XREF=gi:2223141 /DB_XREF=est:ng97e11.s1 /CLONE=IMAGE:942764 /UG=Hs.104258 Homo sapiens mRNA, exon 1, 2, 3, 4, clone:RES4-24A AA493300 NOP14 antisense RNA 1 NOP14-AS1 317648 NR_015453 215142_at AA815276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA815276 /FEA=EST /DB_XREF=gi:2884872 /DB_XREF=est:ai59a01.s1 /CLONE=1375080 /UG=Hs.122959 Huntingtin interacting protein M AA815276 huntingtin interacting protein M HYPM 25763 NM_012274 0046982 // protein heterodimerization activity // inferred from electronic annotation 215143_at AL049437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049437.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586E1120 (from clone DKFZp586E1120). /FEA=mRNA /DB_XREF=gi:4500220 /UG=Hs.100292 Homo sapiens mRNA; cDNA DKFZp586E1120 (from clone DKFZp586E1120) AL049437 DPY19L2 pseudogene 2 DPY19L2P2 349152 NM_182634 /// NR_003561 /// NR_027768 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 215144_at AF007147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007147.1 /DEF=Homo sapiens clone 23712 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852625 /UG=Hs.113166 Homo sapiens clone 23712 mRNA sequence AF007147 215145_s_at AC005378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005378 /DEF=Homo sapiens PAC clone RP5-1137M13 from 7q33-q35 /FEA=CDS /DB_XREF=gi:4508139 /UG=Hs.106552 cell recognition molecule Caspr2 AC005378 contactin associated protein-like 2 CNTNAP2 26047 NM_014141 /// XM_006715919 0007155 // cell adhesion // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007610 // behavior // inferred from mutant phenotype /// 0007612 // learning // inferred from mutant phenotype /// 0008038 // neuron recognition // non-traceable author statement /// 0019226 // transmission of nerve impulse // non-traceable author statement /// 0021756 // striatum development // inferred from expression pattern /// 0021761 // limbic system development // inferred from expression pattern /// 0021794 // thalamus development // inferred from expression pattern /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030534 // adult behavior // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from mutant phenotype /// 0045163 // clustering of voltage-gated potassium channels // inferred from sequence or structural similarity /// 0071109 // superior temporal gyrus development // inferred from expression pattern /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030673 // axolemma // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 215146_s_at AB028966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028966.1 /DEF=Homo sapiens mRNA for KIAA1043 protein, partial cds. /FEA=mRNA /GEN=KIAA1043 /PROD=KIAA1043 protein /DB_XREF=gi:5689422 /UG=Hs.11390 KIAA1043 protein AB028966 tetratricopeptide repeat domain 28 TTC28 23331 NM_001145418 /// NM_015281 /// XM_005261405 /// XM_006724171 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215147_at AF007147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007147.1 /DEF=Homo sapiens clone 23712 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852625 /UG=Hs.113166 Homo sapiens clone 23712 mRNA sequence AF007147 Homo sapiens clone 23712 mRNA sequence. AF007147 215148_s_at AI141541 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI141541 /FEA=EST /DB_XREF=gi:3648998 /DB_XREF=est:qa90b12.x1 /CLONE=IMAGE:1694015 /UG=Hs.17528 amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) AI141541 amyloid beta (A4) precursor protein-binding, family A, member 3 APBA3 9546 NM_004886 /// XM_006722950 /// XM_006722951 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 215149_at AF052109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052109.1 /DEF=Homo sapiens clone 23927 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360416 /UG=Hs.12473 Homo sapiens clone 23927 mRNA sequence AF052109 adherens junctions associated protein 1 AJAP1 55966 NM_001042478 /// NM_018836 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 215150_at AF090896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090896.1 /DEF=Homo sapiens clone HQ0131 PRO0131 mRNA, partial cds. /FEA=mRNA /PROD=PRO0131 /DB_XREF=gi:6690168 /UG=Hs.163001 hypothetical protein PRO0907 AF090896 YOD1 deubiquitinase YOD1 55432 NM_001276320 /// NM_018566 /// XR_247031 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from sequence or structural similarity /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0035523 // protein K29-linked deubiquitination // inferred from direct assay /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1990167 // protein K27-linked deubiquitination // inferred from direct assay /// 1990168 // protein K33-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 215151_at AB014594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014594.2 /DEF=Homo sapiens mRNA for KIAA0694 protein, partial cds. /FEA=mRNA /GEN=KIAA0694 /PROD=KIAA0694 protein /DB_XREF=gi:6683720 /UG=Hs.137579 KIAA0694 gene product AB014594 dedicator of cytokinesis 10 DOCK10 55619 NM_001290263 /// NM_014689 /// NM_017718 /// XM_005246672 /// XM_005246673 /// XM_005246674 /// XM_006712616 /// XM_006712617 /// XM_006712618 /// XM_006712619 /// XM_006712620 /// XM_006712621 /// XM_006712622 /// XM_006712623 /// XM_006712624 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 215152_at AI357042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357042 /FEA=EST /DB_XREF=gi:4108663 /DB_XREF=est:qx62b04.x1 /CLONE=IMAGE:2005903 /UG=Hs.1334 v-myb avian myeloblastosis viral oncogene homolog AI357042 v-myb avian myeloblastosis viral oncogene homolog MYB 4602 NM_001130172 /// NM_001130173 /// NM_001161656 /// NM_001161657 /// NM_001161658 /// NM_001161659 /// NM_001161660 /// NM_005375 /// XM_006715495 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0045624 // positive regulation of T-helper cell differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048538 // thymus development // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // non-traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215153_at AF037070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF037070.1 /DEF=Homo sapiens carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase mRNA, partial cds. /FEA=mRNA /PROD=carboxyl-terminal PDZ ligand of neuronal nitricoxide synthase /DB_XREF=gi:2895554 /UG=Hs.129729 ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain AF037070 nitric oxide synthase 1 (neuronal) adaptor protein NOS1AP 9722 NM_001126060 /// NM_001164757 /// NM_014697 0042981 // regulation of apoptotic process // non-traceable author statement /// 0045428 // regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0050998 // nitric-oxide synthase binding // inferred from sequence or structural similarity 215154_at AL080134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080134.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G043 (from clone DKFZp434G043). /FEA=mRNA /DB_XREF=gi:5262575 /UG=Hs.168762 Homo sapiens mRNA; cDNA DKFZp434G043 (from clone DKFZp434G043) AL080134 unc-51 like autophagy activating kinase 2 ULK2 9706 NM_001142610 /// NM_014683 /// XM_006721606 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215155_at J04178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J04178.1 /DEF=Human abnormal beta-hexosaminidase alpha chain (HEXA) mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:184001 /UG=Hs.166299 Human abnormal beta-hexosaminidase alpha chain (HEXA) mRNA, partial cds J04178 hexosaminidase A (alpha polypeptide) HEXA 3073 NM_000520 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 215156_at AL109709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109709.2 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 43432. /FEA=mRNA /DB_XREF=gi:9187596 /UG=Hs.167456 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 43432 AL109709 WD repeat domain 61 WDR61 80349 NM_025234 /// XM_005254698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 2001162 // positive regulation of histone H3-K79 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215157_x_at AI734929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI734929 /FEA=EST /DB_XREF=gi:5056453 /DB_XREF=est:at14d04.x1 /CLONE=IMAGE:2355079 /UG=Hs.172182 poly(A)-binding protein, cytoplasmic 1 AI734929 poly(A) binding protein, cytoplasmic 1 PABPC1 26986 NM_002568 /// XM_005250861 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // traceable author statement /// 0048255 // mRNA stabilization // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008143 // poly(A) binding // traceable author statement /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0008494 // translation activator activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 215158_s_at AK022531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022531.1 /DEF=Homo sapiens cDNA FLJ12469 fis, clone NT2RM1000874, highly similar to Homo sapiens death effector domain-containing testicular molecule mRNA. /FEA=mRNA /DB_XREF=gi:10433972 /UG=Hs.169681 death effector domain-containing AK022531 death effector domain containing DEDD 9191 NM_001039711 /// NM_001039712 /// NM_004216 /// NM_032998 /// XM_005245597 /// XM_005245598 /// XM_005245599 /// XM_005245600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 215159_s_at AI239732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI239732 /FEA=EST /DB_XREF=gi:3835129 /DB_XREF=est:qh43d07.x1 /CLONE=IMAGE:1847437 /UG=Hs.220324 hypothetical protein FLJ13052 AI239732 NAD kinase NADK 65220 NM_001198993 /// NM_001198994 /// NM_001198995 /// NM_023018 /// XM_005244778 /// XM_006710837 /// XM_006710838 /// XM_006710839 /// XR_241040 0006741 // NADP biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // non-traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215160_x_at AL441988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL441988 /DEF=Human DNA sequence from clone RP11-348I14 on chromosome 20 Contains ESTs, STSs, GSSs and two CpG islands. Contains a novel gene, a novel gene similar to FRG1 encoding FSHD (fascioscapulohumeral muscular dystrophy) region gene 1 and part of a novel... /FEA=mRNA_3 /DB_XREF=gi:11990063 /UG=Hs.203772 FSHD region gene 1 AL441988 protein FRG1-like /// FSHD region gene 1 pseudogene LOC100289097 /// LOC642236 642236 /// 100289097 NR_033907 /// XR_426484 /// XR_430284 215161_at AW016039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW016039 /FEA=EST /DB_XREF=gi:5864796 /DB_XREF=est:UI-H-BI0p-abf-c-11-0-UI.s1 /CLONE=IMAGE:2711445 /UG=Hs.199068 similar to calciumcalmodulin dependent protein kinases AW016039 calcium/calmodulin-dependent protein kinase IG CAMK1G 57172 NM_020439 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215162_at AB020691 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020691.1 /DEF=Homo sapiens mRNA for KIAA0884 protein, partial cds. /FEA=mRNA /GEN=KIAA0884 /PROD=KIAA0884 protein /DB_XREF=gi:4240256 /UG=Hs.198232 KIAA0884 protein AB020691 Ral GTPase activating protein, alpha subunit 1 (catalytic) RALGAPA1 253959 NM_001283043 /// NM_001283044 /// NM_014990 /// NM_194301 /// XM_005267491 /// XM_005267492 /// XM_005267493 /// XM_005267498 /// XM_006720098 /// XM_006720099 /// XM_006720100 /// XM_006720101 /// XM_006720102 /// XM_006720103 /// XM_006720104 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // not recorded /// 0032859 // activation of Ral GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005096 // GTPase activator activity // inferred from electronic annotation /// 0017123 // Ral GTPase activator activity // not recorded /// 0017123 // Ral GTPase activator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction 215163_at AK022211 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022211.1 /DEF=Homo sapiens cDNA FLJ12149 fis, clone MAMMA1000421. /FEA=mRNA /DB_XREF=gi:10433557 /UG=Hs.203349 Homo sapiens cDNA FLJ12149 fis, clone MAMMA1000421 AK022211 215164_at AL049279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049279.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I083 (from clone DKFZp564I083). /FEA=mRNA /DB_XREF=gi:4500035 /UG=Hs.202685 Homo sapiens mRNA; cDNA DKFZp564I083 (from clone DKFZp564I083) AL049279 215165_x_at AL080099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080099.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G1272 (from clone DKFZp564G1272); partial cds. /FEA=mRNA /GEN=DKFZp564G1272 /PROD=hypothetical protein /DB_XREF=gi:5262522 /UG=Hs.2057 uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) AL080099 uridine monophosphate synthetase UMPS 7372 NM_000373 /// NR_033434 /// NR_033437 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004588 // orotate phosphoribosyltransferase activity // inferred from direct assay /// 0004588 // orotate phosphoribosyltransferase activity // traceable author statement /// 0004590 // orotidine-5'-phosphate decarboxylase activity // inferred from direct assay /// 0004590 // orotidine-5'-phosphate decarboxylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 215166_at AB028953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028953.1 /DEF=Homo sapiens mRNA for KIAA1030 protein, partial cds. /FEA=mRNA /GEN=KIAA1030 /PROD=KIAA1030 protein /DB_XREF=gi:5689396 /UG=Hs.204121 KIAA1030 protein AB028953 immunoglobulin superfamily, member 9B IGSF9B 22997 NM_001277285 /// NM_014987 /// XM_006718795 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215167_at BE567032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE567032 /FEA=EST /DB_XREF=gi:9810752 /DB_XREF=est:601341180F1 /CLONE=IMAGE:3683563 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) BE567032 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 215168_at AK023063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023063.1 /DEF=Homo sapiens cDNA FLJ13001 fis, clone NT2RP3000341, highly similar to Homo sapiens mitochondrial inner membrane preprotein translocase Tim17a mRNA, nuclear gene encoding mitochondrial protein. /FEA=mRNA /DB_XREF=gi:10434808 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A AK023063 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 215169_at BE885244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE885244 /FEA=EST /DB_XREF=gi:10334020 /DB_XREF=est:601506311F1 /CLONE=IMAGE:3907947 /UG=Hs.214646 KIAA0447 gene product BE885244 solute carrier family 35, member E2 /// solute carrier family 35, member E2B SLC35E2 /// SLC35E2B 9906 /// 728661 NM_001110781 /// NM_001199787 /// NM_001290264 /// NM_182838 /// XM_006710870 /// XM_006710871 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215170_s_at AB020719 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020719.1 /DEF=Homo sapiens mRNA for KIAA0912 protein, partial cds. /FEA=mRNA /GEN=KIAA0912 /PROD=KIAA0912 protein /DB_XREF=gi:4240312 /UG=Hs.207802 KIAA0912 protein AB020719 centrosomal protein 152kDa CEP152 22995 NM_001194998 /// NM_014985 /// XM_006720437 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0098535 // de novo centriole assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0098536 // deuterosome // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 215171_s_at AK023063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023063.1 /DEF=Homo sapiens cDNA FLJ13001 fis, clone NT2RP3000341, highly similar to Homo sapiens mitochondrial inner membrane preprotein translocase Tim17a mRNA, nuclear gene encoding mitochondrial protein. /FEA=mRNA /DB_XREF=gi:10434808 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A AK023063 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 215172_at AL050040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050040.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566K0524 (from clone DKFZp566K0524); partial cds. /FEA=mRNA /GEN=DKFZp566K0524 /PROD=hypothetical protein /DB_XREF=gi:4884281 /UG=Hs.227651 DKFZP566K0524 protein AL050040 protein tyrosine phosphatase, non-receptor type 20B PTPN20B 26095 NM_001042357 /// NM_001042358 /// NM_001042359 /// NM_001042360 /// NM_001042361 /// NM_001042362 /// NM_001042363 /// NM_001042364 /// NM_001042365 /// NM_001042387 /// NM_001042389 /// NM_001042390 /// NM_001042391 /// NM_001042392 /// NM_001042393 /// NM_001042394 /// NM_001042395 /// NM_001042396 /// NM_001042397 /// NM_015605 /// XM_005270315 /// XM_005277652 /// XM_006717754 /// XM_006717755 /// XM_006717756 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 215173_at N46852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N46852 /FEA=EST /DB_XREF=gi:1188018 /DB_XREF=est:yy73d05.s1 /CLONE=IMAGE:279177 /UG=Hs.285625 Homo sapiens mRNA; cDNA DKFZp434A119 (from clone DKFZp434A119) N46852 dynein, axonemal, assembly factor 1 DNAAF1 123872 NM_178452 /// XM_006721129 /// XM_006721130 0001947 // heart looping // inferred from mutant phenotype /// 0003341 // cilium movement // inferred from mutant phenotype /// 0003356 // regulation of cilium beat frequency // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0035469 // determination of pancreatic left/right asymmetry // inferred from mutant phenotype /// 0036158 // outer dynein arm assembly // inferred from mutant phenotype /// 0036159 // inner dynein arm assembly // inferred from mutant phenotype /// 0044458 // motile cilium assembly // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred by curator /// 0060972 // left/right pattern formation // inferred from mutant phenotype /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0045502 // dynein binding // inferred from mutant phenotype 215174_at AL021026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021026 /DEF=Homo sapiens DNA sequence from PAC 127D3 on chromosome 1q23-25. Contains FMO2 and FMO3 genes for Flavin-containing Monooxygenase 2 and Flavin-containing Monooxygenase 3 (Dimethylaniline Monooxygenase (N-Oxide 3, EC1.14.13.8, Dimethylaniline Oxidas... /FEA=CDS_1 /DB_XREF=gi:3171875 /UG=Hs.232447 Homo sapiens DNA sequence from PAC 127D3 on chromosome 1q23-25. Contains FMO2 and FMO3 genes for Flavin-containing Monooxygenase 2 and Flavin-containing Monooxygenase 3 (Dimethylaniline Monooxygenase (N-Oxide 3, EC1.14.13.8, Dimethylaniline Oxidase 3, FMO AL021026 flavin containing monooxygenase 6 pseudogene FMO6P 388714 NR_002601 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 215175_at AB023212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023212.1 /DEF=Homo sapiens mRNA for KIAA0995 protein, partial cds. /FEA=mRNA /GEN=KIAA0995 /PROD=KIAA0995 protein /DB_XREF=gi:4589633 /UG=Hs.225967 KIAA0995 protein AB023212 pecanex homolog (Drosophila) PCNX 22990 NM_014982 /// XM_005267420 /// XM_005267421 /// XM_005267422 /// XM_005267423 /// XM_005267424 /// XM_005267425 /// XM_005267426 /// XM_005267427 /// XM_005267428 /// XM_005267429 /// XM_006720082 /// XR_245672 /// XR_245673 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215176_x_at AW404894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW404894 /FEA=EST /DB_XREF=gi:6923951 /DB_XREF=est:UI-HF-BL0-acn-f-07-0-UI.r1 /CLONE=IMAGE:3059844 /UG=Hs.314762 Homo sapiens partial IGKV gene for immunoglobulin kappa chain variable region, clone 30 AW404894 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215177_s_at AV733308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV733308 /FEA=EST /DB_XREF=gi:10850853 /DB_XREF=est:AV733308 /CLONE=cdAADA11 /UG=Hs.227730 integrin, alpha 6 AV733308 integrin, alpha 6 ITGA6 3655 NM_000210 /// NM_001079818 /// XM_006712510 /// XM_006712511 0007044 // cell-substrate junction assembly // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0034676 // integrin alpha6-beta4 complex // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215178_x_at AV724215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV724215 /FEA=EST /DB_XREF=gi:10828379 /DB_XREF=est:AV724215 /CLONE=HTBBOD12 /UG=Hs.264330 N-acylsphingosine amidohydrolase (acid ceramidase)-like AV724215 N-acylethanolamine acid amidase NAAA 27163 NM_001042402 /// NM_014435 /// XM_005262920 /// XM_005262921 /// XM_005262923 /// XM_005262924 /// XM_005262925 /// XM_006714178 /// XM_006714179 /// XM_006714180 /// XM_006714181 /// XR_427542 0006629 // lipid metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from direct assay 215179_x_at AK023843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023843.1 /DEF=Homo sapiens cDNA FLJ13781 fis, clone PLACE4000465. /FEA=mRNA /DB_XREF=gi:10435902 /UG=Hs.252820 Homo sapiens cDNA FLJ13781 fis, clone PLACE4000465 AK023843 placental growth factor PGF 5228 NM_001207012 /// NM_001293643 /// NM_002632 /// XM_005267761 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060688 // regulation of morphogenesis of a branching structure // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from mutant phenotype /// 0008201 // heparin binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215180_at AL109703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109703.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 25206. /FEA=mRNA /DB_XREF=gi:5689812 /UG=Hs.25314 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 25206 AL109703 RP11-429B14.4 215181_at AF035300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035300.1 /DEF=Homo sapiens clone 23663 mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:2661057 /UG=Hs.264157 hypothetical protein similar to cadherin 22 AF035300 cadherin 22, type 2 CDH22 64405 NM_021248 /// XM_006723856 /// XM_006723857 /// XM_006723858 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215182_x_at AL050122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050122.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586E121 (from clone DKFZp586E121). /FEA=mRNA /DB_XREF=gi:4884330 /UG=Hs.274511 Homo sapiens mRNA; cDNA DKFZp586E121 (from clone DKFZp586E121) AL050122 215183_at AF090886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090886.1 /DEF=Homo sapiens clone HQ0072. /FEA=mRNA /DB_XREF=gi:6690153 /UG=Hs.284192 Homo sapiens clone HQ0072 AF090886 215184_at AK026801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026801.1 /DEF=Homo sapiens cDNA: FLJ23148 fis, clone LNG09313, highly similar to AB018001 Homo sapiens mRNA for Death-associated protein kinase 2. /FEA=mRNA /DB_XREF=gi:10439740 /UG=Hs.266662 Homo sapiens cDNA: FLJ23148 fis, clone LNG09313, highly similar to AB018001 Homo sapiens mRNA for Death-associated protein kinase 2 AK026801 death-associated protein kinase 2 DAPK2 23604 NM_014326 /// XM_005254265 /// XM_005254266 /// XM_005254268 /// XM_005254270 /// XM_006720449 /// XM_006720450 /// XM_006720451 /// XM_006720452 /// XM_006720453 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043276 // anoikis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 1900119 // positive regulation of execution phase of apoptosis // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034423 // autophagic vacuole lumen // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 215185_at AK024177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024177.1 /DEF=Homo sapiens cDNA FLJ14115 fis, clone MAMMA1001760. /FEA=mRNA /DB_XREF=gi:10436493 /UG=Hs.266263 Homo sapiens cDNA FLJ14115 fis, clone MAMMA1001760 AK024177 long intergenic non-protein coding RNA 963 LINC00963 100506190 NR_038955 215186_at AL050074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050074.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566F1946 (from clone DKFZp566F1946). /FEA=mRNA /DB_XREF=gi:4884307 /UG=Hs.27406 Homo sapiens mRNA; cDNA DKFZp566F1946 (from clone DKFZp566F1946) AL050074 TBC1 domain family, member 30 TBC1D30 23329 NM_015279 /// XM_006719300 /// XM_006719301 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 215187_at AK023417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023417.1 /DEF=Homo sapiens cDNA FLJ13355 fis, clone PLACE1000048. /FEA=mRNA /DB_XREF=gi:10435347 /UG=Hs.272246 hypothetical protein FLJ11292 AK023417 uncharacterized protein FLJ11292 FLJ11292 55338 NM_018382 215188_at AF339785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339785.1 /DEF=Homo sapiens clone IMAGE:1963178, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507323 /UG=Hs.270256 Homo sapiens clone IMAGE:1963178, mRNA sequence AF339785 serine/threonine kinase 24 STK24 8428 NM_001032296 /// NM_001286649 /// NM_003576 /// XM_005254078 /// XM_005254079 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048679 // regulation of axon regeneration // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215189_at X99142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X99142.1 /DEF=H.sapiens mRNA for hair keratin, hHb6. /FEA=mRNA /GEN=hHb6 /PROD=type II intermediate filament of hair keratin /DB_XREF=gi:1903219 /UG=Hs.278658 keratin, hair, basic, 6 (monilethrix) X99142 keratin 86 /// uncharacterized LOC100509764 KRT86 /// LOC100509764 3892 /// 100509764 NM_002284 /// XM_005268866 /// XR_111293 0007010 // cytoskeleton organization // non-traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 215190_at AV717062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV717062 /FEA=EST /DB_XREF=gi:10814214 /DB_XREF=est:AV717062 /CLONE=DCBCEG06 /UG=Hs.274553 Homo sapiens cDNA FLJ10906 fis, clone OVARC1000035 AV717062 eukaryotic translation initiation factor 3, subunit M EIF3M 10480 NM_006360 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0002183 // cytoplasmic translational initiation // not recorded /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 215191_at AW836210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW836210 /FEA=EST /DB_XREF=gi:7930184 /DB_XREF=est:RC3-LT0023-200100-012-e08 /UG=Hs.278648 Homo sapiens cDNA FLJ14085 fis, clone HEMBB1002534 AW836210 215192_at D38500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38500.1 /DEF=Human PMS6 mRNA (yeast mismatch repair gene PMS1 homologue), partial cds (C-terminal region). /FEA=mRNA /GEN=PMS6 /DB_XREF=gi:1304122 /UG=Hs.278468 postmeiotic segregation increased 2-like 4 D38500 postmeiotic segregation increased 2 pseudogene 4 PMS2P4 5382 NR_022007 /// NR_046297 /// NR_046299 0006298 // mismatch repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement 0032300 // mismatch repair complex // inferred from electronic annotation 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 215193_x_at AJ297586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ297586.1 /DEF=Homo sapiens mRNA for MHC class II antigen (HLA-DRB1 gene), DRB1*0402 allele. /FEA=CDS /GEN=HLA-DRB1 /PROD=MHC class II antigen /DB_XREF=gi:10185079 /UG=Hs.279930 major histocompatibility complex, class II, DR beta 3 AJ297586 major histocompatibility complex, class II, DQ beta 1 /// major histocompatibility complex, class II, DR beta 1 /// major histocompatibility complex, class II, DR beta 3 /// major histocompatibility complex, class II, DR beta 4 /// HLA class II histocompatibility antigen, DRB1-10 beta chain-like /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// HLA-DRB1 /// HLA-DRB3 /// HLA-DRB4 /// LOC100996809 /// LOC101060835 3119 /// 3123 /// 3125 /// 3126 /// 100996809 /// 101060835 NM_001243961 /// NM_001243962 /// NM_001243965 /// NM_002123 /// NM_002124 /// NM_021983 /// NM_022555 /// XM_003960955 /// XM_005276082 /// XM_006710174 /// XM_006710243 /// XM_006725752 /// XM_006725860 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 /// XR_430944 /// XR_430980 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0006955 // immune response // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032673 // regulation of interleukin-4 production // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0051262 // protein tetramerization // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity /// 2001179 // regulation of interleukin-10 secretion // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0042605 // peptide antigen binding // inferred from direct assay 215194_at AF035594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035594.1 /DEF=Homo sapiens protein kinase C-alpha mRNA, partial 3 UTR. /FEA=mRNA /DB_XREF=gi:3168857 /UG=Hs.279856 Homo sapiens protein kinase C-alpha mRNA, partial 3 UTR AF035594 protein kinase C, alpha PRKCA 5578 NM_002737 /// XM_006721972 /// XR_243672 /// XR_243673 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0036289 // peptidyl-serine autophosphorylation // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation /// 0090330 // regulation of platelet aggregation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2000707 // positive regulation of dense core granule biogenesis // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004698 // calcium-dependent protein kinase C activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215195_at AF035594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035594.1 /DEF=Homo sapiens protein kinase C-alpha mRNA, partial 3 UTR. /FEA=mRNA /DB_XREF=gi:3168857 /UG=Hs.279856 Homo sapiens protein kinase C-alpha mRNA, partial 3 UTR AF035594 protein kinase C, alpha PRKCA 5578 NM_002737 /// XM_006721972 /// XR_243672 /// XR_243673 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007194 // negative regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035408 // histone H3-T6 phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0036289 // peptidyl-serine autophosphorylation // inferred from electronic annotation /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071322 // cellular response to carbohydrate stimulus // inferred from electronic annotation /// 0090330 // regulation of platelet aggregation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2000707 // positive regulation of dense core granule biogenesis // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004698 // calcium-dependent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0035403 // histone kinase activity (H3-T6 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215196_at AU158566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158566 /FEA=EST /DB_XREF=gi:11020087 /DB_XREF=est:AU158566 /CLONE=PLACE3000322 /UG=Hs.287635 Homo sapiens cDNA FLJ14312 fis, clone PLACE3000322 AU158566 215197_at AK023838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023838.1 /DEF=Homo sapiens cDNA FLJ13776 fis, clone PLACE4000387. /FEA=mRNA /DB_XREF=gi:10435896 /UG=Hs.287595 Homo sapiens cDNA FLJ13776 fis, clone PLACE4000387 AK023838 215198_s_at AU147402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147402 /FEA=EST /DB_XREF=gi:11008923 /DB_XREF=est:AU147402 /CLONE=MAMMA1000567 /UG=Hs.287496 Homo sapiens cDNA FLJ12160 fis, clone MAMMA1000567 AU147402 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 215199_at AU147402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147402 /FEA=EST /DB_XREF=gi:11008923 /DB_XREF=est:AU147402 /CLONE=MAMMA1000567 /UG=Hs.287496 Homo sapiens cDNA FLJ12160 fis, clone MAMMA1000567 AU147402 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 215200_x_at AK022362 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022362.1 /DEF=Homo sapiens cDNA FLJ12300 fis, clone MAMMA1001854. /FEA=mRNA /DB_XREF=gi:10433744 /UG=Hs.287510 Homo sapiens cDNA FLJ12300 fis, clone MAMMA1001854 AK022362 215201_at AW166925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW166925 /FEA=EST /DB_XREF=gi:6398450 /DB_XREF=est:xg68e01.x1 /CLONE=IMAGE:2633496 /UG=Hs.289037 Homo sapiens cDNA FLJ14135 fis, clone MAMMA1002728 AW166925 RALBP1 associated Eps domain containing 1 REPS1 85021 NM_001128617 /// NM_001286611 /// NM_001286612 /// NM_031922 /// XM_005267177 /// XM_005267178 /// XM_005267179 /// XM_006715587 /// XR_245555 0006898 // receptor-mediated endocytosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215202_at AK025313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025313.1 /DEF=Homo sapiens cDNA: FLJ21660 fis, clone COL08818. /FEA=mRNA /DB_XREF=gi:10437803 /UG=Hs.287678 Homo sapiens cDNA: FLJ21660 fis, clone COL08818 AK025313 glucuronidase, beta pseudogene 11 GUSBP11 91316 NR_024448 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 215203_at AW438464 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW438464 /FEA=EST /DB_XREF=gi:6973770 /DB_XREF=est:xu43g07.x1 /CLONE=IMAGE:2804508 /UG=Hs.288760 Homo sapiens cDNA FLJ12327 fis, clone MAMMA1002140 AW438464 golgin A4 GOLGA4 2803 NM_001172713 /// NM_002078 /// XM_005265069 /// XM_005265070 /// XM_005265071 /// XM_005265072 /// XM_005265073 /// XM_005265074 /// XM_005265075 /// XM_006713110 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from physical interaction 215204_at AU147295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147295 /FEA=EST /DB_XREF=gi:11008816 /DB_XREF=est:AU147295 /CLONE=MAMMA1000264 /UG=Hs.288575 Homo sapiens cDNA FLJ14090 fis, clone MAMMA1000264 AU147295 215205_x_at S83390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S83390.1 /DEF=T3 receptor-associating cofactor-1 human, fetal liver, mRNA, 2930 nt. /FEA=mRNA /GEN=T3 receptor-associating cofactor-1, TRAC-1 /PROD=T3 receptor-associating cofactor-1 /DB_XREF=gi:1911769 /UG=Hs.287994 nuclear receptor co-repressor 2 S83390 nuclear receptor corepressor 2 NCOR2 9612 NM_001077261 /// NM_001206654 /// NM_006312 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0072365 // regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 215206_at AK025143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025143.1 /DEF=Homo sapiens cDNA: FLJ21490 fis, clone COL05464. /FEA=mRNA /DB_XREF=gi:10437602 /UG=Hs.288700 Homo sapiens cDNA: FLJ21490 fis, clone COL05464 AK025143 215207_x_at BF695847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF695847 /FEA=EST /DB_XREF=gi:11981255 /DB_XREF=est:601852205F1 /CLONE=IMAGE:4076232 /UG=Hs.301917 YDD19 protein BF695847 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) /// nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 NUS1 /// NUS1P3 11049 /// 116150 NM_138459 0001525 // angiogenesis // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from genetic interaction /// 0055092 // sterol homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016765 // transferase activity, transferring alkyl or aryl (other than methyl) groups // inferred from electronic annotation 215208_x_at AK021571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021571.1 /DEF=Homo sapiens cDNA FLJ11509 fis, clone HEMBA1002166. /FEA=mRNA /DB_XREF=gi:10432777 /UG=Hs.289093 Homo sapiens cDNA FLJ11509 fis, clone HEMBA1002166 AK021571 ribosomal protein L35a RPL35A 6165 NM_000996 /// XM_005269350 /// XM_005269351 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 215209_at AU143984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU143984 /FEA=EST /DB_XREF=gi:11005505 /DB_XREF=est:AU143984 /CLONE=HEMBA1000568 /UG=Hs.301645 Homo sapiens cDNA FLJ10021 fis, clone HEMBA1000568 AU143984 SEC24 family member D SEC24D 9871 NM_014822 /// XM_005263378 /// XM_005263379 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 215210_s_at S72422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S72422.1 /DEF=E2k=alpha-ketoglutarate dehydrogenase complex dihydrolipoyl succinyltransferase human, fetal brain, mRNA, 2987 nt. /FEA=mRNA /GEN=E2k /PROD=alpha-ketoglutarate dehydrogenase complexdihydrolipoyl succinyltransferase /DB_XREF=gi:632883 /UG=Hs.296348 E2k S72422 dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) DLST 1743 NM_001244883 /// NM_001933 /// NR_033814 /// NR_045209 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006554 // lysine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033512 // L-lysine catabolic process to acetyl-CoA via saccharopine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045252 // oxoglutarate dehydrogenase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004149 // dihydrolipoyllysine-residue succinyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215211_at AF054994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF054994.1 /DEF=Homo sapiens clone 23832 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005709 /UG=Hs.31290 Homo sapiens clone 23832 mRNA sequence AF054994 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 RRN3P1 730092 NR_003370 215212_at AU147166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147166 /FEA=EST /DB_XREF=gi:11008687 /DB_XREF=est:AU147166 /CLONE=HEMBB1002582 /UG=Hs.301683 Homo sapiens cDNA FLJ12091 fis, clone HEMBB1002582 AU147166 215213_at AU146949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146949 /FEA=EST /DB_XREF=gi:11008470 /DB_XREF=est:AU146949 /CLONE=HEMBB1001952 /UG=Hs.301817 Homo sapiens cDNA FLJ12044 fis, clone HEMBB1001952 AU146949 nucleoporin 54kDa NUP54 53371 NM_001278603 /// NM_017426 /// NR_103780 /// NR_103781 /// NR_103782 /// XM_006714236 /// XM_006714237 /// XM_006714238 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation 215214_at H53689 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H53689 /FEA=EST /DB_XREF=gi:993836 /DB_XREF=est:yu38g07.r1 /CLONE=IMAGE:236124 /UG=Hs.306239 Homo sapiens clone ASPBLL54 immunoglobulin lambda light chain VJ region mRNA, partial cds H53689 immunoglobulin lambda constant 1 (Mcg marker) /// immunoglobulin lambda variable 3-25 /// IGLC1 /// IGLV3-25 /// IGLV3-25 3537 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215215_s_at AC004381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004381 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-44M2 /FEA=CDS_1 /DB_XREF=gi:2982169 /UG=Hs.307353 Homo sapiens Chromosome 16 BAC clone CIT987SK-44M2 AC004381 exonuclease NEF-sp LOC81691 81691 NM_001144924 /// NM_001199053 /// NM_030941 /// XM_005255604 /// XM_005255606 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215216_at AA779495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA779495 /FEA=EST /DB_XREF=gi:2838826 /DB_XREF=est:af23b12.s1 /CLONE=IMAGE:1032479 /UG=Hs.302441 vacuolar protein sorting 16 (yeast homolog) AA779495 vacuolar protein sorting 16 homolog (S. cerevisiae) VPS16 64601 NM_022575 /// NM_080413 /// NM_080414 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 215217_at AA476303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA476303 /FEA=EST /DB_XREF=gi:2204514 /DB_XREF=est:zw29d09.s1 /CLONE=IMAGE:770705 /UG=Hs.306357 Homo sapiens isolate donor N clone N168K immunoglobulin kappa light chain variable region mRNA, partial cds AA476303 immunoglobulin kappa constant IGKC 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 215218_s_at AC004144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004144 /DEF=Homo sapiens chromosome 19, overlapping cosmids R28707 and R34001 /FEA=CDS /DB_XREF=gi:2887496 /UG=Hs.307350 Homo sapiens chromosome 19, overlapping cosmids R28707 and R34001 AC004144 WD repeat domain 62 WDR62 284403 NM_001083961 /// NM_173636 /// XM_005258809 0007399 // nervous system development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0022008 // neurogenesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215219_at AK025095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025095.1 /DEF=Homo sapiens cDNA: FLJ21442 fis, clone COL04429, highly similar to HSA237839 Homo sapiens mRNA for hypothetical protein. /FEA=mRNA /DB_XREF=gi:10437542 /UG=Hs.306763 Homo sapiens cDNA: FLJ21442 fis, clone COL04429, highly similar to HSA237839 Homo sapiens mRNA for hypothetical protein AK025095 dopey family member 2 DOPEY2 9980 NM_005128 /// XM_006724068 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215220_s_at AK023111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023111.1 /DEF=Homo sapiens cDNA FLJ13049 fis, clone NT2RP3001428, highly similar to NUCLEOPROTEIN TPR. /FEA=mRNA /DB_XREF=gi:10434882 /UG=Hs.306642 Homo sapiens cDNA FLJ13049 fis, clone NT2RP3001428, highly similar to NUCLEOPROTEIN TPR AK023111 translocated promoter region, nuclear basket protein TPR 7175 NM_003292 /// XM_005245471 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0009318 // exodeoxyribonuclease VII complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008855 // exodeoxyribonuclease VII activity // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 215221_at AK025064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025064.1 /DEF=Homo sapiens cDNA: FLJ21411 fis, clone COL03986. /FEA=mRNA /DB_XREF=gi:10437503 /UG=Hs.306758 Homo sapiens cDNA: FLJ21411 fis, clone COL03986 AK025064 215222_x_at AK023406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023406.1 /DEF=Homo sapiens cDNA FLJ13344 fis, clone OVARC1002050, highly similar to Homo sapiens mRNA for actin binding protein ABP620. /FEA=mRNA /DB_XREF=gi:10435330 /UG=Hs.321395 Homo sapiens cDNA FLJ13344 fis, clone OVARC1002050, highly similar to Homo sapiens mRNA for actin binding protein ABP620 AK023406 microtubule-actin crosslinking factor 1 MACF1 23499 NM_012090 /// NM_033044 /// XM_005270694 /// XM_005270695 /// XM_005270696 /// XM_005270697 /// XM_005270698 /// XM_005270700 /// XM_006710519 /// XM_006710520 /// XM_006710521 /// XM_006710522 /// XM_006710523 /// XM_006710524 /// XM_006710525 /// XM_006710526 /// XM_006710527 /// XM_006710528 /// XM_006710529 /// XM_006710530 /// XM_006710531 /// XM_006710532 /// XM_006710533 /// XM_006710534 /// XM_006710535 /// XM_006710536 /// XM_006710537 /// XM_006710538 /// XM_006710539 /// XM_006710540 0001707 // mesoderm formation // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006620 // posttranslational protein targeting to membrane // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010632 // regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // non-traceable author statement 215223_s_at W46388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W46388 /FEA=EST /DB_XREF=gi:1331076 /DB_XREF=est:zc32c08.s1 /CLONE=IMAGE:324014 /UG=Hs.318885 superoxide dismutase 2, mitochondrial W46388 uncharacterized LOC100129518 /// superoxide dismutase 2, mitochondrial LOC100129518 /// SOD2 6648 /// 100129518 NM_000636 /// NM_001024465 /// NM_001024466 /// NR_037166 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from mutant phenotype /// 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001315 // age-dependent response to reactive oxygen species // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0003032 // detection of oxygen // inferred from electronic annotation /// 0003069 // vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034021 // response to silicon dioxide // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048773 // erythrophore differentiation // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0030145 // manganese ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215224_at AK025200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025200.1 /DEF=Homo sapiens cDNA: FLJ21547 fis, clone COL06206. /FEA=mRNA /DB_XREF=gi:10437664 /UG=Hs.322680 Homo sapiens cDNA: FLJ21547 fis, clone COL06206 AK025200 small nucleolar RNA, H/ACA box 21 SNORA21 619505 NR_002576 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006610 // ribosomal protein import into nucleus // non-traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215225_s_at Z94154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z94154.1 /DEF=H.sapiens mRNA for P2Y-like G-protein coupled receptor. /FEA=mRNA /PROD=P2Y-like G-protein coupled receptor /DB_XREF=gi:2695873 /UG=Hs.46453 G protein-coupled receptor 17 Z94154 G protein-coupled receptor 17 GPR17 2840 NM_001161415 /// NM_001161416 /// NM_001161417 /// NM_005291 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement 215226_at AK000786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000786.1 /DEF=Homo sapiens cDNA FLJ20779 fis, clone COL05077. /FEA=mRNA /DB_XREF=gi:7021088 /UG=Hs.321583 Homo sapiens cDNA FLJ20779 fis, clone COL05077 AK000786 exophilin 5 EXPH5 23086 NM_001144763 /// NM_001144765 /// NM_015065 /// XM_005271461 /// XM_005271462 /// XM_005271463 0003334 // keratinocyte development // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay 0017137 // Rab GTPase binding // inferred from physical interaction 215227_x_at BG035989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG035989 /FEA=EST /DB_XREF=gi:12430674 /DB_XREF=est:602326204F1 /CLONE=IMAGE:4414128 /UG=Hs.75393 acid phosphatase 1, soluble BG035989 acid phosphatase 1, soluble ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NM_177554 /// NR_024080 /// XR_426957 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 215228_at AA166895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA166895 /FEA=EST /DB_XREF=gi:1745059 /DB_XREF=est:zq39f05.s1 /CLONE=IMAGE:632097 /UG=Hs.46296 nescient helix loop helix 2 AA166895 nescient helix loop helix 2 NHLH2 4808 NM_001111061 /// NM_005599 /// XM_006710666 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007617 // mating behavior // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 215229_at AF007131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007131.1 /DEF=Homo sapiens clone 23963 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852605 /UG=Hs.48483 Homo sapiens clone 23963 mRNA sequence AF007131 uncharacterized LOC100129973 LOC100129973 100129973 NR_102751 215230_x_at AA679705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA679705 /FEA=EST /DB_XREF=gi:2660227 /DB_XREF=est:ah15e04.s1 /CLONE=IMAGE:1156734 /UG=Hs.4835 eukaryotic translation initiation factor 3, subunit 8 (110kD) AA679705 eukaryotic translation initiation factor 3, subunit C /// eukaryotic translation initiation factor 3, subunit C-like EIF3C /// EIF3CL 8663 /// 728689 NM_001037808 /// NM_001099661 /// NM_001199142 /// NM_001267574 /// NM_001286478 /// NM_003752 /// XM_005255535 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215231_at AU144309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144309 /FEA=EST /DB_XREF=gi:11005830 /DB_XREF=est:AU144309 /CLONE=HEMBA1001533 /UG=Hs.55830 Homo sapiens cDNA FLJ10068 fis, clone HEMBA1001533 AU144309 protein kinase, AMP-activated, gamma 2 non-catalytic subunit PRKAG2 51422 NM_001040633 /// NM_016203 /// NM_024429 /// XM_005250002 /// XM_005250003 /// XM_005250004 /// XM_005250005 /// XM_005250006 /// XM_005250007 /// XM_005250009 /// XM_006716021 0005977 // glycogen metabolic process // inferred from mutant phenotype /// 0006110 // regulation of glycolytic process // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0016126 // sterol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046320 // regulation of fatty acid oxidation // traceable author statement /// 0046324 // regulation of glucose import // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from mutant phenotype /// 0008607 // phosphorylase kinase regulator activity // inferred from mutant phenotype /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from mutant phenotype /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay 215232_at AK023797 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023797.1 /DEF=Homo sapiens cDNA FLJ13735 fis, clone PLACE3000155, weakly similar to Homo sapiens mRNA for KIAA0672 protein. /FEA=mRNA /DB_XREF=gi:10435840 /UG=Hs.6336 KIAA0672 gene product AK023797 Rho GTPase activating protein 44 ARHGAP44 9912 NM_014859 /// XM_005256888 /// XM_005256889 /// XM_005256890 /// XM_005256891 /// XM_006721615 0006887 // exocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 215233_at AA351360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA351360 /FEA=EST /DB_XREF=gi:2003690 /DB_XREF=est:EST59093 /UG=Hs.72660 phosphatidylserine receptor AA351360 jumonji domain containing 6 JMJD6 23210 NM_001081461 /// NM_015167 0001568 // blood vessel development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018395 // peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042116 // macrophage activation // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0070078 // histone H3-R2 demethylation // inferred from direct assay /// 0070079 // histone H4-R3 demethylation // inferred from direct assay /// 0070782 // phosphatidylserine exposure on apoptotic cell surface // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0033746 // histone demethylase activity (H3-R2 specific) // inferred from direct assay /// 0033749 // histone demethylase activity (H4-R3 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0070815 // peptidyl-lysine 5-dioxygenase activity // inferred from direct assay 215234_at AW301235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301235 /FEA=EST /DB_XREF=gi:6710912 /DB_XREF=est:xs69c06.x1 /CLONE=IMAGE:2774890 /UG=Hs.66185 Homo Sapiens mRNA, partial cDNA sequence from cDNA selection, DCR1-16.0 AW301235 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DYRK1A 1859 NM_001396 /// NM_101395 /// NM_130436 /// NM_130437 /// NM_130438 /// XM_005260931 /// XM_005260933 /// XM_006723976 /// XM_006723977 /// XM_006723978 /// XM_006723979 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007399 // nervous system development // traceable author statement /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0090312 // positive regulation of protein deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043621 // protein self-association // inferred from sequence or structural similarity /// 0048156 // tau protein binding // inferred from sequence or structural similarity 215235_at AL110273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110273.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P0562 (from clone DKFZp564P0562); partial cds. /FEA=mRNA /GEN=DKFZp564P0562 /PROD=hypothetical protein /DB_XREF=gi:5817091 /UG=Hs.77196 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) AL110273 spectrin, alpha, non-erythrocytic 1 SPTAN1 6709 NM_001130438 /// NM_001195532 /// NM_003127 /// XM_006717245 /// XM_006717246 /// XM_006717247 /// XM_006717248 /// XM_006717249 /// XM_006717250 /// XM_006717251 /// XM_006717252 /// XM_006717253 /// XM_006717254 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215236_s_at AV721177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV721177 /FEA=EST /DB_XREF=gi:10818329 /DB_XREF=est:AV721177 /CLONE=HTBAKF08 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein AV721177 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 215237_at AW450751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450751 /FEA=EST /DB_XREF=gi:6991527 /DB_XREF=est:UI-H-BI3-akq-f-11-0-UI.s1 /CLONE=IMAGE:2735372 /UG=Hs.8021 KIAA1058 protein AW450751 dedicator of cytokinesis 9 DOCK9 23348 NM_001130048 /// NM_001130049 /// NM_001130050 /// NM_015296 /// XM_005254034 /// XM_005254035 /// XM_005254036 /// XM_006719922 /// XM_006719923 /// XM_006719924 /// XM_006719925 /// XM_006719926 /// XM_006719927 /// XM_006719928 /// XM_006719929 /// XM_006719930 /// XM_006719931 /// XM_006719932 /// XM_006719933 /// XM_006719934 /// XM_006719935 /// XM_006719936 /// XM_006719937 /// XM_006719938 /// XM_006719939 /// XM_006719940 /// XM_006719941 /// XM_006719942 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation 215238_s_at AW450751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450751 /FEA=EST /DB_XREF=gi:6991527 /DB_XREF=est:UI-H-BI3-akq-f-11-0-UI.s1 /CLONE=IMAGE:2735372 /UG=Hs.8021 KIAA1058 protein AW450751 dedicator of cytokinesis 9 DOCK9 23348 NM_001130048 /// NM_001130049 /// NM_001130050 /// NM_015296 /// XM_005254034 /// XM_005254035 /// XM_005254036 /// XM_006719922 /// XM_006719923 /// XM_006719924 /// XM_006719925 /// XM_006719926 /// XM_006719927 /// XM_006719928 /// XM_006719929 /// XM_006719930 /// XM_006719931 /// XM_006719932 /// XM_006719933 /// XM_006719934 /// XM_006719935 /// XM_006719936 /// XM_006719937 /// XM_006719938 /// XM_006719939 /// XM_006719940 /// XM_006719941 /// XM_006719942 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation 215239_x_at AU132789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU132789 /FEA=EST /DB_XREF=gi:10993328 /DB_XREF=est:AU132789 /CLONE=NT2RP4000545 /UG=Hs.89732 zinc finger protein 273 AU132789 zinc finger protein 273 ZNF273 10793 NM_021148 /// NM_033548 /// NR_003099 /// XM_006715840 /// XM_006715841 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215240_at AI189839 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189839 /FEA=EST /DB_XREF=gi:3741048 /DB_XREF=est:qd23e12.x1 /CLONE=IMAGE:1724590 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) AI189839 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 215241_at AJ300461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ300461.1 /DEF=Homo sapiens mRNA for C11ORF25 gene. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:13160035 /UG=Hs.91791 Homo sapiens mRNA for C11ORF25 gene AJ300461 anoctamin 3 ANO3 63982 NM_031418 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005229 // intracellular calcium activated chloride channel activity // inferred from direct assay 215242_at AL035301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035301.1 /DEF=H.sapiens gene from PAC 106H8. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4200219 /UG=Hs.97375 H.sapiens gene from PAC 106H8 AL035301 phosphatidylinositol glycan anchor biosynthesis, class C PIGC 5279 NM_002642 /// NM_153747 /// XM_006711383 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation 215243_s_at AF099730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF099730 /DEF=Homo sapiens connexin 31 (GJB3) gene, complete cds /FEA=mRNA /DB_XREF=gi:4009519 /UG=Hs.98485 gap junction protein, beta 3, 31kD (connexin 31) AF099730 gap junction protein, beta 3, 31kDa GJB3 2707 NM_001005752 /// NM_024009 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215244_at AI479306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI479306 /FEA=EST /DB_XREF=gi:4372474 /DB_XREF=est:tm27a02.x1 /CLONE=IMAGE:2157770 /UG=Hs.93522 putative non-coding transcript (DiGeorge critical region 5) AI479306 DiGeorge syndrome critical region gene 5 (non-protein coding) DGCR5 26220 NR_002733 /// NR_045121 /// NR_110533 /// XM_003846300 /// XM_003846633 /// XM_003960801 /// XR_109700 /// XR_254060 /// XR_425299 /// XR_430416 /// XR_430417 /// XR_433678 /// XR_433679 215245_x_at AA830884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA830884 /FEA=EST /DB_XREF=gi:2903983 /DB_XREF=est:oc57a09.s1 /CLONE=IMAGE:1353784 /UG=Hs.89764 fragile X mental retardation 1 AA830884 fragile X mental retardation 1 FMR1 2332 NM_001185075 /// NM_001185076 /// NM_001185081 /// NM_001185082 /// NM_002024 /// NR_033699 /// NR_033700 0006810 // transport // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042788 // polysomal ribosome // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215246_at AK000089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000089.1 /DEF=Homo sapiens cDNA FLJ20082 fis, clone COL03245. /FEA=mRNA /DB_XREF=gi:7019950 /UG=Hs.323797 Homo sapiens cDNA FLJ20082 fis, clone COL03245 AK000089 La ribonucleoprotein domain family, member 7 LARP7 51574 NM_001267039 /// NM_015454 /// NM_016648 /// NR_049768 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215247_at AI561253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI561253 /FEA=EST /DB_XREF=gi:4511594 /DB_XREF=est:tq27g06.x1 /CLONE=IMAGE:2210074 /UG=Hs.306649 Homo sapiens cDNA FLJ13403 fis, clone PLACE1001517, moderately similar to Homo sapiens gene for glycosylphosphatidylinositol anchor attachment 1 (GPAA1) AI561253 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) pseudogene LOC100288570 100288570 NR_037627 215248_at AU145003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145003 /FEA=EST /DB_XREF=gi:11006524 /DB_XREF=est:AU145003 /CLONE=HEMBA1003598 /UG=Hs.287428 Homo sapiens cDNA FLJ11581 fis, clone HEMBA1003598 AU145003 growth factor receptor-bound protein 10 GRB10 2887 NM_001001549 /// NM_001001550 /// NM_001001555 /// NM_005311 /// XM_005271760 /// XM_005271761 /// XM_005271765 /// XM_005271766 /// XM_005271767 /// XM_006715703 /// XM_006715704 /// XM_006715705 0007165 // signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 215249_at AK021571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021571.1 /DEF=Homo sapiens cDNA FLJ11509 fis, clone HEMBA1002166. /FEA=mRNA /DB_XREF=gi:10432777 /UG=Hs.289093 Homo sapiens cDNA FLJ11509 fis, clone HEMBA1002166 AK021571 ribosomal protein L35a RPL35A 6165 NM_000996 /// XM_005269350 /// XM_005269351 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 215250_at AU147317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147317 /FEA=EST /DB_XREF=gi:11008838 /DB_XREF=est:AU147317 /CLONE=MAMMA1000340 /UG=Hs.287491 Homo sapiens cDNA FLJ12140 fis, clone MAMMA1000340 AU147317 ER membrane protein complex subunit 3 EMC3 55831 NM_018447 /// XM_005265321 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 215251_at AA595276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA595276 /FEA=EST /DB_XREF=gi:2410626 /DB_XREF=est:no35a05.s1 /CLONE=IMAGE:1102640 /UG=Hs.243804 Homo sapiens cDNA FLJ13800 fis, clone THYRO1000156 AA595276 215252_at AW814026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW814026 /FEA=EST /DB_XREF=gi:7907020 /DB_XREF=est:RC6-ST0198-071199-021-G02 /UG=Hs.273621 Homo sapiens cDNA: FLJ21350 fis, clone COL02751 AW814026 0006457 // protein folding // traceable author statement /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction 215253_s_at AL049369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049369.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D0518 (from clone DKFZp586D0518). /FEA=mRNA /DB_XREF=gi:4500160 /UG=Hs.250724 Homo sapiens mRNA; cDNA DKFZp586D0518 (from clone DKFZp586D0518) AL049369 regulator of calcineurin 1 RCAN1 1827 NM_001285389 /// NM_001285391 /// NM_001285392 /// NM_001285393 /// NM_004414 /// NM_203417 /// NM_203418 /// XM_005260929 /// XM_005260930 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 215254_at AL049369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049369.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D0518 (from clone DKFZp586D0518). /FEA=mRNA /DB_XREF=gi:4500160 /UG=Hs.250724 Homo sapiens mRNA; cDNA DKFZp586D0518 (from clone DKFZp586D0518) AL049369 regulator of calcineurin 1 RCAN1 1827 NM_001285389 /// NM_001285391 /// NM_001285392 /// NM_001285393 /// NM_004414 /// NM_203417 /// NM_203418 /// XM_005260929 /// XM_005260930 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 215255_at AB028953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028953.1 /DEF=Homo sapiens mRNA for KIAA1030 protein, partial cds. /FEA=mRNA /GEN=KIAA1030 /PROD=KIAA1030 protein /DB_XREF=gi:5689396 /UG=Hs.204121 KIAA1030 protein AB028953 immunoglobulin superfamily, member 9B IGSF9B 22997 NM_001277285 /// NM_014987 /// XM_006718795 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215256_x_at AC002398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002398 /DEF=Human DNA from chromosome 19-specific cosmid F25965, genomic sequence /FEA=CDS_3 /DB_XREF=gi:2529398 /UG=Hs.169550 Human DNA from chromosome 19-specific cosmid F25965, genomic sequence AC002398 Rho GTPase activating protein 33 ARHGAP33 115703 NM_001172630 /// NM_052948 /// XM_005258487 /// XM_005258488 /// XM_005258489 /// XM_006722999 /// XM_006723000 /// XM_006723001 /// XM_006723002 /// XM_006723003 /// XR_430187 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 215257_at AF308298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF308298.1 /DEF=Homo sapiens serologically defined breast cancer antigen NY-BR-84 mRNA, partial cds. /FEA=mRNA /PROD=serologically defined breast cancer antigenNY-BR-84 /DB_XREF=gi:12060846 /UG=Hs.157309 Homo sapiens serologically defined breast cancer antigen NY-BR-84 mRNA, partial cds AF308298 ERGIC and golgi 3 ERGIC3 51614 NM_015966 /// NM_198398 /// XM_006723804 /// XM_006723805 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 215258_at AC005525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005525 /DEF=Homo sapiens chromosome 19, cosmid F22162 /FEA=CDS_2 /DB_XREF=gi:3451333 /UG=Hs.129064 Homo sapiens chromosome 19, cosmid F22162 AC005525 cell adhesion molecule 4 CADM4 199731 NM_145296 /// XM_005258620 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215259_s_at AC005525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005525 /DEF=Homo sapiens chromosome 19, cosmid F22162 /FEA=CDS_2 /DB_XREF=gi:3451333 /UG=Hs.129064 Homo sapiens chromosome 19, cosmid F22162 AC005525 cell adhesion molecule 4 CADM4 199731 NM_145296 /// XM_005258620 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215260_s_at X52078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52078.1 /DEF=Human transcription factor (ITF-1) mRNA, 3 end. /FEA=mRNA /PROD=ITF-1 DNA binding protein /DB_XREF=gi:33981 /UG=Hs.101047 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12E47) X52078 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 215261_at AF052091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052091.1 /DEF=Homo sapiens clone 23578 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360397 /UG=Hs.159388 Homo sapiens clone 23578 mRNA sequence AF052091 215262_at AF052160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052160.1 /DEF=Homo sapiens clone 24629 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360471 /UG=Hs.142570 Homo sapiens clone 24629 mRNA sequence AF052160 215263_at BF509566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF509566 /FEA=EST /DB_XREF=gi:11592864 /DB_XREF=est:UI-H-BI4-apf-b-04-0-UI.s1 /CLONE=IMAGE:3086935 /UG=Hs.159249 zinc finger, X-linked, duplicated A BF509566 zinc finger, X-linked, duplicated A /// zinc finger, X-linked, duplicated B ZXDA /// ZXDB 7789 /// 158586 NM_007156 /// NM_007157 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 215264_at AW196403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW196403 /FEA=EST /DB_XREF=gi:6475633 /DB_XREF=est:xm33b01.x1 /CLONE=IMAGE:2685961 /UG=Hs.140400 empty spiracles (Drosophila) homolog 1 AW196403 empty spiracles homeobox 1 EMX1 2016 NM_001040404 /// NM_004097 /// XM_005264203 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 215265_at BF515060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF515060 /FEA=EST /DB_XREF=gi:11600239 /DB_XREF=est:UI-H-BW1-anr-h-02-0-UI.s1 /CLONE=IMAGE:3083378 /UG=Hs.140400 empty spiracles (Drosophila) homolog 1 BF515060 215266_at AL096732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096732.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N074 (from clone DKFZp434N074). /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:5419864 /UG=Hs.144852 Homo sapiens mRNA; cDNA DKFZp434N074 (from clone DKFZp434N074) AL096732 dynein, axonemal, heavy chain 3 DNAH3 55567 NM_017539 /// XM_006721062 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 215267_s_at AI127885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI127885 /FEA=EST /DB_XREF=gi:3596399 /DB_XREF=est:qc42d08.x1 /CLONE=IMAGE:1712271 /UG=Hs.143026 KIAA1087 protein AI127885 solute carrier family 8 (sodium/calcium exchanger), member 2 SLC8A2 6543 NM_015063 /// XM_005259172 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005432 // calcium:sodium antiporter activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 215268_at AW663712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW663712 /FEA=EST /DB_XREF=gi:7456250 /DB_XREF=est:hj12e06.x1 /CLONE=IMAGE:2981602 /UG=Hs.159183 KIAA0754 protein AW663712 KIAA0754 KIAA0754 643314 NM_015038 215269_at AI922538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI922538 /FEA=EST /DB_XREF=gi:5658502 /DB_XREF=est:wm89c11.x1 /CLONE=IMAGE:2443124 /UG=Hs.152860 Homo sapiens mRNA; cDNA DKFZp586C091 (from clone DKFZp586C091) AI922538 trafficking protein particle complex 10 TRAPPC10 7109 NM_001001723 /// NM_003274 /// XM_005261168 /// XM_005261169 /// XM_006724046 /// XM_006724047 0006810 // transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015081 // sodium ion transmembrane transporter activity // traceable author statement 215270_at U94354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U94354.1 /DEF=Human lunatic fringe mRNA, partial cds. /FEA=mRNA /PROD=lunatic fringe /DB_XREF=gi:2204350 /UG=Hs.159142 lunatic fringe (Drosophila) homolog U94354 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase LFNG 3955 NM_001040167 /// NM_001040168 /// NM_001166355 /// NM_002304 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007386 // compartment pattern specification // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008593 // regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // non-traceable author statement /// 0014807 // regulation of somitogenesis // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215271_at BF432086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF432086 /FEA=EST /DB_XREF=gi:11444200 /DB_XREF=est:nab85f07.x1 /CLONE=IMAGE:3274525 /UG=Hs.156369 hypothetical protein similar to tenascin-R BF432086 tenascin N TNN 63923 NM_022093 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0016049 // cell growth // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 215272_at R59977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R59977 /FEA=EST /DB_XREF=gi:830672 /DB_XREF=est:yh08b07.s1 /CLONE=IMAGE:42485 /UG=Hs.158196 transcriptional adaptor 3 (ADA3, yeast homolog)-like (PCAF histone acetylase complex) R59977 8-oxoguanine DNA glycosylase OGG1 4968 NM_002542 /// NM_016819 /// NM_016820 /// NM_016821 /// NM_016826 /// NM_016827 /// NM_016828 /// NM_016829 /// XM_005265185 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from direct assay /// 0045007 // depurination // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051147 // regulation of muscle cell differentiation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from mutant phenotype /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051835 // positive regulation of synapse structural plasticity // inferred from mutant phenotype /// 0060999 // positive regulation of dendritic spine development // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008534 // oxidized purine nucleobase lesion DNA N-glycosylase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation /// 0034039 // 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity // inferred from electronic annotation 215273_s_at AK024982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024982.1 /DEF=Homo sapiens cDNA: FLJ21329 fis, clone COL02464. /FEA=mRNA /DB_XREF=gi:10437412 /UG=Hs.158196 transcriptional adaptor 3 (ADA3, yeast homolog)-like (PCAF histone acetylase complex) AK024982 transcriptional adaptor 3 TADA3 10474 NM_001278270 /// NM_006354 /// NM_133480 /// NM_133481 /// NR_103488 /// XM_006712930 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0090043 // regulation of tubulin deacetylation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation 215274_at AI627943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI627943 /FEA=EST /DB_XREF=gi:4664743 /DB_XREF=est:ty83a11.x1 /CLONE=IMAGE:2285660 /UG=Hs.158462 solute carrier family 12 (sodiumchloride transporters), member 3 AI627943 solute carrier family 12 (sodium/chloride transporter), member 3 SLC12A3 6559 NM_000339 /// NM_001126107 /// NM_001126108 /// XM_005256119 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006821 // chloride transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015378 // sodium:chloride symporter activity // traceable author statement 215275_at AW963138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW963138 /FEA=EST /DB_XREF=gi:8152974 /DB_XREF=est:EST375211 /UG=Hs.302040 Homo sapiens DNA sequence from PAC 434O14 on chromosome 1q32.3.-41. Contains the HSD11B1 gene for Hydroxysteroid (11-beta) Dehydrogenase 1, the ADORA2BP adenosine A2b receptor LIKE pseudogene, the IRF6 gene for Interferon Regulatory Factor 6 and two novel AW963138 TRAF3 interacting protein 3 TRAF3IP3 80342 NM_001287754 /// NM_025228 /// NR_109871 /// XM_005273279 /// XM_005273280 /// XR_247044 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 215276_at AL133571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133571.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F1135 (from clone DKFZp434F1135). /FEA=mRNA /DB_XREF=gi:6599149 /UG=Hs.116128 Homo sapiens mRNA; cDNA DKFZp434F1135 (from clone DKFZp434F1135) AL133571 WAP four-disulfide core domain 8 WFDC8 90199 NM_130896 /// NM_181510 /// XM_005260607 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 215277_at AA481656 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA481656 /FEA=EST /DB_XREF=gi:2211208 /DB_XREF=est:zv06c11.r1 /CLONE=IMAGE:752852 /UG=Hs.115642 Human protocadherin 42 mRNA, 3 end of cds for alternative splicing PC42-8 AA481656 protocadherin 1 PCDH1 5097 NM_001278613 /// NM_001278615 /// NM_002587 /// NM_032420 /// XM_005268452 /// XM_005268453 /// XM_005268454 /// XM_005268455 /// XM_005268456 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215278_at AF052090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052090.1 /DEF=Homo sapiens clone 23950 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360396 /UG=Hs.106620 Homo sapiens clone 23950 mRNA sequence AF052090 215279_at AF035278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035278.1 /DEF=Homo sapiens clone 23676 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661027 /UG=Hs.100841 Homo sapiens clone 23676 mRNA sequence AF035278 215280_s_at AK023850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023850.1 /DEF=Homo sapiens cDNA FLJ13788 fis, clone SKNMC1000046, highly similar to Homo sapiens liprin-alpha3 mRNA. /FEA=mRNA /DB_XREF=gi:10435912 /UG=Hs.109299 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 AK023850 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 PPFIA3 8541 NM_003660 /// NR_103842 /// XM_006723450 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 215281_x_at AK000199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000199.1 /DEF=Homo sapiens cDNA FLJ20192 fis, clone COLF0778, highly similar to AB007930 Homo sapiens mRNA for KIAA0461 perotein. /FEA=mRNA /DB_XREF=gi:7020127 /UG=Hs.107088 KIAA0461 protein AK000199 pogo transposable element with ZNF domain POGZ 23126 NM_001194937 /// NM_001194938 /// NM_015100 /// NM_145796 /// NM_207171 /// XM_005244999 /// XM_005245000 /// XM_005245001 /// XM_005245003 /// XM_005245004 /// XM_005245005 /// XM_005245006 /// XM_006711237 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215282_at BE677493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE677493 /FEA=EST /DB_XREF=gi:10038034 /DB_XREF=est:7d86d05.x1 /CLONE=IMAGE:3279849 /UG=Hs.106909 DKFZP566D193 protein BE677493 anaphase promoting complex subunit 13 ANAPC13 25847 NM_001242374 /// NM_001242375 /// NM_015391 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005680 // anaphase-promoting complex // inferred from direct assay 215283_at U79248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79248.1 /DEF=Human clone 23826 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710195 /UG=Hs.12484 Human clone 23826 mRNA sequence U79248 long intergenic non-protein coding RNA 667 LINC00667 339290 NR_015389 215284_at AF070575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070575.1 /DEF=Homo sapiens clone 24407 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387946 /UG=Hs.12432 Homo sapiens clone 24407 mRNA sequence AF070575 215285_s_at AA927671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA927671 /FEA=EST /DB_XREF=gi:3076491 /DB_XREF=est:om72a06.s1 /CLONE=IMAGE:1552690 /UG=Hs.123637 putative homeodomain transcription factor AA927671 putative homeodomain transcription factor 1 PHTF1 10745 NM_006608 /// XM_005270383 /// XM_005270384 /// XM_005270385 /// XM_005270387 /// XM_006710296 /// XM_006710297 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 215286_s_at AL050389 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050389.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F013 (from clone DKFZp564F013). /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4914570 /UG=Hs.128653 hypothetical protein DKFZp564F013 AL050389 putative homeodomain transcription factor 2 PHTF2 57157 NM_001127357 /// NM_001127358 /// NM_001127359 /// NM_001127360 /// NM_020432 /// XM_005250508 /// XM_005250509 /// XM_006716063 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 215287_at AA975427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA975427 /FEA=EST /DB_XREF=gi:3151219 /DB_XREF=est:oq28g02.s1 /CLONE=IMAGE:1587698 /UG=Hs.128434 Homo sapiens ELISC-1 mRNA, partial cds AA975427 striatin, calmodulin binding protein STRN 6801 NM_003162 /// XM_005264519 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // non-traceable author statement /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 215288_at AI769824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI769824 /FEA=EST /DB_XREF=gi:5236333 /DB_XREF=est:wj20b04.x1 /CLONE=IMAGE:2403343 /UG=Hs.131910 transient receptor potential channel 2 AI769824 transient receptor potential cation channel, subfamily C, member 2, pseudogene TRPC2 7221 NR_002720 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005262 // calcium channel activity // inferred from electronic annotation 215289_at BE892698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE892698 /FEA=EST /DB_XREF=gi:10353302 /DB_XREF=est:601433917F1 /CLONE=IMAGE:3918989 /UG=Hs.129709 Homo sapiens chromosome 19, cosmid R30217 BE892698 zinc finger protein 749 ZNF749 388567 NM_001023561 /// XM_006723211 /// XM_006723212 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215290_at AI480014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI480014 /FEA=EST /DB_XREF=gi:4373182 /DB_XREF=est:tm71b09.x1 /CLONE=IMAGE:2163545 /UG=Hs.13415 Homo sapiens clone 24571 mRNA sequence AI480014 215291_at AL022238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022238 /DEF=Human DNA sequence from clone RP5-1042K10 on chromosome 22q13.1-13.2 Contains the ADSL gene for Adenylosuccinate lyase (EC 4.3.2.2, Adenylosuccinase, ASL) and 4 novel genes (one with probable rabGAP domains and Src homology domain 3). Contains EST... /FEA=mRNA_1 /DB_XREF=gi:4176442 /UG=Hs.134751 Human DNA sequence from clone RP5-1042K10 on chromosome 22q13.1-13.2 Contains the ADSL gene for Adenylosuccinate lyase (EC 4.3.2.2, Adenylosuccinase, ASL) and 4 novel genes (one with probable rabGAP domains and Src homology domain 3). Contains ESTs, STSs, AL022238 megakaryoblastic leukemia (translocation) 1 MKL1 57591 NM_001282660 /// NM_001282661 /// NM_001282662 /// NM_020831 /// XM_005261691 /// XM_005261692 /// XM_005261694 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051145 // smooth muscle cell differentiation // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003779 // actin binding // inferred from direct assay /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction 215292_s_at AL022238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022238 /DEF=Human DNA sequence from clone RP5-1042K10 on chromosome 22q13.1-13.2 Contains the ADSL gene for Adenylosuccinate lyase (EC 4.3.2.2, Adenylosuccinase, ASL) and 4 novel genes (one with probable rabGAP domains and Src homology domain 3). Contains EST... /FEA=mRNA_1 /DB_XREF=gi:4176442 /UG=Hs.134751 Human DNA sequence from clone RP5-1042K10 on chromosome 22q13.1-13.2 Contains the ADSL gene for Adenylosuccinate lyase (EC 4.3.2.2, Adenylosuccinase, ASL) and 4 novel genes (one with probable rabGAP domains and Src homology domain 3). Contains ESTs, STSs, AL022238 megakaryoblastic leukemia (translocation) 1 MKL1 57591 NM_001282660 /// NM_001282661 /// NM_001282662 /// NM_020831 /// XM_005261691 /// XM_005261692 /// XM_005261694 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048536 // spleen development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from mutant phenotype /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215293_s_at AL049261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049261.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E053 (from clone DKFZp564E053). /FEA=mRNA /DB_XREF=gi:4500009 /UG=Hs.133968 FGF receptor activating protein 1 AL049261 post-GPI attachment to proteins 2 PGAP2 27315 NM_001145438 /// NM_001256235 /// NM_001256236 /// NM_001256237 /// NM_001256238 /// NM_001256239 /// NM_001256240 /// NM_001283038 /// NM_001283039 /// NM_001283040 /// NM_014489 /// NR_027016 /// NR_027017 /// NR_027018 /// NR_045923 /// NR_045925 /// NR_045926 /// NR_045927 /// NR_045929 /// NR_104270 /// NR_104271 /// NR_104272 /// XM_006718181 /// XM_006718182 /// XM_006718183 /// XM_006718184 /// XM_006718185 /// XM_006718186 /// XM_006718187 /// XM_006718188 /// XM_006718189 /// XM_006718190 /// XM_006718191 /// XM_006718192 /// XM_006718193 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity 215294_s_at AK026426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026426.1 /DEF=Homo sapiens cDNA: FLJ22773 fis, clone KAIA1473, highly similar to HUMSNF2L Human global transcription activator homologous sequence mRNA. /FEA=mRNA /DB_XREF=gi:10439287 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 AK026426 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay 215295_at Y15718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15718.1 /DEF=Homo sapiens mRNA for dystrobrevin B DTN-B2. /FEA=mRNA /GEN=DTN-B2 /PROD=dystrobrevin B DTN-B2 /DB_XREF=gi:3133086 /UG=Hs.13451 dystrobrevin, beta Y15718 dystrobrevin, beta DTNB 1838 NM_001256303 /// NM_001256304 /// NM_001256308 /// NM_021907 /// NM_033147 /// NM_033148 /// NM_183360 /// NM_183361 /// XM_005264182 /// XM_005264183 /// XM_005264184 /// XM_005264186 /// XM_006711960 /// XM_006711961 /// XM_006711962 0005737 // cytoplasm // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215296_at AK027000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027000.1 /DEF=Homo sapiens cDNA: FLJ23347 fis, clone HEP13727. /FEA=mRNA /DB_XREF=gi:10440000 /UG=Hs.18586 KIAA0451 gene product AK027000 CDC42 binding protein kinase alpha (DMPK-like) CDC42BPA 8476 NM_003607 /// NM_014826 /// XM_005273317 /// XM_005273318 /// XM_005273320 /// XM_005273321 /// XM_005273322 /// XM_005273323 /// XM_005273324 /// XM_006711834 /// XM_006711835 /// XM_006711836 /// XM_006711837 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007097 // nuclear migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215297_at AK022806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022806.1 /DEF=Homo sapiens cDNA FLJ12744 fis, clone NT2RP2000715. /FEA=mRNA /DB_XREF=gi:10434418 /UG=Hs.139425 Homo sapiens cDNA FLJ12744 fis, clone NT2RP2000715 AK022806 uncharacterized LOC441204 LOC441204 441204 NR_015364 215298_at U79300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79300.1 /DEF=Human clone 23629 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710285 /UG=Hs.135587 Human clone 23629 mRNA sequence U79300 RP11-714L20.1 215299_x_at U37025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U37025 /DEF=Human phenol sulfotransferase (STP1) gene, last exon and partial cds /FEA=mRNA /DB_XREF=gi:1353413 /UG=Hs.142 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 U37025 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 SULT1A1 6817 NM_001055 /// NM_177529 /// NM_177530 /// NM_177534 /// NM_177536 /// XM_005255522 /// XM_006721078 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0009308 // amine metabolic process // traceable author statement /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004062 // aryl sulfotransferase activity // inferred from direct assay /// 0004062 // aryl sulfotransferase activity // traceable author statement /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay /// 0050294 // steroid sulfotransferase activity // inferred from direct assay 215300_s_at AK022172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022172.1 /DEF=Homo sapiens cDNA FLJ12110 fis, clone MAMMA1000020, highly similar to H.sapiens mRNA for flavin-containing monooxygenase 5 (FMO5). /FEA=mRNA /DB_XREF=gi:10433507 /UG=Hs.14286 flavin containing monooxygenase 5 AK022172 flavin containing monooxygenase 5 FMO5 2330 NM_001144829 /// NM_001144830 /// NM_001461 /// XM_005272946 /// XM_005272947 /// XM_005272948 /// XM_006711244 /// XM_006711245 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 215301_at AL512697 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512697.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547F134 (from clone DKFZp547F134). /FEA=mRNA /DB_XREF=gi:12224853 /UG=Hs.147587 Homo sapiens mRNA; cDNA DKFZp547F134 (from clone DKFZp547F134) AL512697 synaptonemal complex central element protein 1-like SYCE1L 100130958 NM_001129979 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation 0000795 // synaptonemal complex // inferred from electronic annotation 215302_at AU150691 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150691 /FEA=EST /DB_XREF=gi:11012212 /DB_XREF=est:AU150691 /CLONE=NT2RP2003367 /UG=Hs.153321 Homo sapiens cDNA FLJ10577 fis, clone NT2RP2003367 AU150691 uncharacterized LOC257152 LOC257152 257152 215303_at BE046461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE046461 /FEA=EST /DB_XREF=gi:8363514 /DB_XREF=est:hn47g05.x2 /CLONE=IMAGE:3026840 /UG=Hs.159412 Homo sapiens clone 24628 mRNA sequence BE046461 doublecortin-like kinase 1 DCLK1 9201 NM_001195415 /// NM_001195416 /// NM_001195430 /// NM_004734 /// XM_005266592 /// XM_006719893 0001764 // neuron migration // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0016197 // endosomal transport // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215304_at U79293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79293.1 /DEF=Human clone 23948 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710274 /UG=Hs.159264 Human clone 23948 mRNA sequence U79293 215305_at H79306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H79306 /FEA=EST /DB_XREF=gi:1057395 /DB_XREF=est:yu28a01.s1 /CLONE=IMAGE:235080 /UG=Hs.166074 Human platelet-derived growth factor alpha-receptor (PDGFRA) mRNA, exons 13-16 H79306 platelet-derived growth factor receptor, alpha polypeptide PDGFRA 5156 NM_006206 /// XM_005265743 /// XM_006714039 /// XM_006714040 /// XM_006714041 0001553 // luteinization // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030539 // male genitalia development // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035790 // platelet-derived growth factor receptor-alpha signaling pathway // inferred from mutant phenotype /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2000739 // regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from mutant phenotype /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 215306_at AL049443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049443.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N2020 (from clone DKFZp586N2020). /FEA=mRNA /DB_XREF=gi:4500224 /UG=Hs.161283 Homo sapiens mRNA; cDNA DKFZp586N2020 (from clone DKFZp586N2020) AL049443 215307_at AL109722 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109722.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 31619. /FEA=mRNA /DB_XREF=gi:5689814 /UG=Hs.170079 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 31619 AL109722 zinc finger protein 529 ZNF529 57711 NM_001145649 /// NM_001145650 /// NM_020951 /// NR_027239 /// XM_006723302 /// XM_006723303 /// XM_006723304 /// XM_006723305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215308_at AF052148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052148.1 /DEF=Homo sapiens clone 24507 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360458 /UG=Hs.169744 Homo sapiens clone 24507 mRNA sequence AF052148 X-ray repair complementing defective repair in Chinese hamster cells 6 XRCC6 2547 NM_001288976 /// NM_001288977 /// NM_001288978 /// NM_001469 0000723 // telomere maintenance // traceable author statement /// 0006266 // DNA ligation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0071475 // cellular hyperosmotic salinity response // inferred from electronic annotation /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement 0000783 // nuclear telomere cap complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043564 // Ku70:Ku80 complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from mutant phenotype 215309_at BG429154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG429154 /FEA=EST /DB_XREF=gi:13335660 /DB_XREF=est:602498007F1 /CLONE=IMAGE:4612008 /UG=Hs.169190 Human DNA sequence from clone 733D15 on chromosome Xp11.3. Contains a Zinc-finger (pseudo?) gene and GSSs BG429154 zinc finger protein 674 ZNF674 641339 NM_001039891 /// NM_001146291 /// NM_001190417 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215310_at AF038181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF038181.1 /DEF=Homo sapiens clone 23607 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2795901 /UG=Hs.167825 Homo sapiens clone 23607 mRNA sequence AF038181 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 215311_at AL109696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109696.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 21920. /FEA=mRNA /DB_XREF=gi:5689771 /UG=Hs.185701 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 21920 AL109696 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 215312_at AA621286 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA621286 /FEA=EST /DB_XREF=gi:2525225 /DB_XREF=est:zu83e09.s1 /CLONE=IMAGE:744616 /UG=Hs.179697 Human DNA damage repair and recombination protein RAD52 pseudogene mRNA, partial cds AA621286 215313_x_at AA573862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA573862 /FEA=EST /DB_XREF=gi:2348377 /DB_XREF=est:nk08f01.s1 /CLONE=IMAGE:1012921 /UG=Hs.181244 major histocompatibility complex, class I, A AA573862 major histocompatibility complex, class I, A HLA-A 3105 NM_001242758 /// NM_002116 /// XM_005275331 /// XM_006725750 /// XM_006725751 /// XM_006725857 /// XM_006725858 /// XM_006725859 /// XM_006725946 /// XM_006726046 /// XM_006726047 /// XM_006726135 /// XM_006726136 /// XM_006726137 /// XR_430999 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from direct assay /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 2000568 // positive regulation of memory T cell activation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005797 // Golgi medial cisterna // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030881 // beta-2-microglobulin binding // inferred from direct assay /// 0030881 // beta-2-microglobulin binding // inferred from sequence or structural similarity /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0042608 // T cell receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046977 // TAP binding // inferred from direct assay 215314_at AU146646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146646 /FEA=EST /DB_XREF=gi:11008167 /DB_XREF=est:AU146646 /CLONE=HEMBB1001096 /UG=Hs.179752 Homo sapiens cDNA FLJ10270 fis, clone HEMBB1001096 AU146646 215315_at AC003682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003682 /DEF=Homo sapiens chromosome 19, overlapping cosmids F18547, F11133, R27945, R28830 and R32804 /FEA=CDS_5 /DB_XREF=gi:3264845 /UG=Hs.183512 Homo sapiens chromosome 19, overlapping cosmids F18547, F11133, R27945, R28830 and R32804 AC003682 zinc finger protein 549 ZNF549 256051 NM_001199295 /// NM_153263 /// XM_006723128 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215316_at AL080180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080180.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M091 (from clone DKFZp434M091). /FEA=mRNA /DB_XREF=gi:5262656 /UG=Hs.182293 Homo sapiens mRNA; cDNA DKFZp434M091 (from clone DKFZp434M091) AL080180 215317_at AL109696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109696.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 21920. /FEA=mRNA /DB_XREF=gi:5689771 /UG=Hs.185701 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 21920 AL109696 215318_at AL049782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049782.1 /DEF=Novel human gene mapping to chomosome 13. /FEA=mRNA /DB_XREF=gi:4902604 /UG=Hs.184938 Novel human gene mapping to chomosome 13 AL049782 mitochondrial inner membrane organizing system 1 pseudogene 1 MINOS1P1 100462953 NR_051980 215319_at AC004755 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004755 /DEF=Homo sapiens chromosome 19, fosmid 37502 /FEA=CDS_2 /DB_XREF=gi:3165405 /UG=Hs.184922 Homo sapiens chromosome 19, fosmid 37502 AC004755 ATPase, aminophospholipid transporter, class I, type 8B, member 3 ATP8B3 148229 NM_001178002 /// NM_138813 /// NR_047593 /// XM_006722654 /// XM_006722655 /// XM_006722656 /// XM_006722657 0006200 // ATP catabolic process // inferred from reviewed computational analysis /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from reviewed computational analysis /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from reviewed computational analysis /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215320_at AL080179 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080179.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M131 (from clone DKFZp434M131); partial cds. /FEA=mRNA /GEN=DKFZp434M131 /PROD=hypothetical protein /DB_XREF=gi:5262654 /UG=Hs.189296 DKFZP434M131 protein AL080179 SPATA31 subfamily C, member 2 SPATA31C2 645961 NM_001166137 /// XM_006717234 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215321_at AI825798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI825798 /FEA=EST /DB_XREF=gi:5446469 /DB_XREF=est:td18e08.x1 /CLONE=IMAGE:2076038 /UG=Hs.211388 Homo sapiens BAC clone CTB-60N22 from 7q21 AI825798 RUN domain containing 3B RUNDC3B 154661 NM_001134405 /// NM_001134406 /// NM_138290 /// XM_005250156 /// XM_005250157 /// XM_005250158 215322_at AL080190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080190.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A202 (from clone DKFZp434A202). /FEA=mRNA /DB_XREF=gi:5262670 /UG=Hs.189242 Homo sapiens mRNA; cDNA DKFZp434A202 (from clone DKFZp434A202) AL080190 LON peptidase N-terminal domain and ring finger 1 LONRF1 91694 NM_152271 /// XM_005273685 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215323_at X81895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81895.1 /DEF=H.sapiens GENX-5624 mRNA, 3 UTR. /FEA=mRNA /DB_XREF=gi:2370158 /UG=Hs.194765 H.sapiens GENX-5624 mRNA, 3 UTR X81895 leucine zipper protein 2 LUZP2 338645 NM_001009909 /// NM_001252008 /// NM_001252010 /// XM_005252887 /// XM_005252890 0005576 // extracellular region // inferred from electronic annotation 215324_at AA343027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA343027 /FEA=EST /DB_XREF=gi:1995263 /DB_XREF=est:EST48665 /UG=Hs.193606 Homo sapiens PAC clone RP5-1093O17 from 7q11.23-q21 AA343027 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D SEMA3D 223117 NM_152754 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215325_x_at AC004221 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004221 /DEF=Homo sapiens DNA from chromosome 19, cosmid R29144 (LLNLR-252D12) and overlapping PCR product, complete sequence /FEA=CDS_2 /DB_XREF=gi:9665053 /UG=Hs.193187 Homo sapiens DNA from chromosome 19, cosmid R29144 (LLNLR-252D12) and overlapping PCR product, complete sequence AC004221 chromosome 19 open reading frame 26 C19orf26 255057 NM_152769 /// XM_005259528 /// XM_006722714 /// XM_006722715 /// XM_006722716 /// XR_430134 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215326_at AB032968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032968.1 /DEF=Homo sapiens mRNA for KIAA1142 protein, partial cds. /FEA=mRNA /GEN=KIAA1142 /PROD=KIAA1142 protein /DB_XREF=gi:6329958 /UG=Hs.20447 protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs AB032968 p21 protein (Cdc42/Rac)-activated kinase 4 PAK4 10298 NM_001014831 /// NM_001014832 /// NM_001014833 /// NM_001014834 /// NM_001014835 /// NM_005884 /// XM_006722971 /// XM_006722972 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215327_at AI675458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI675458 /FEA=EST /DB_XREF=gi:4875938 /DB_XREF=est:wb99f11.x1 /CLONE=IMAGE:2313837 /UG=Hs.206984 Human cosmid CRI-JC2015 at D10S289 in 10sp13 AI675458 RP11-414H17.5 215328_at AB023170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023170.1 /DEF=Homo sapiens mRNA for KIAA0953 protein, partial cds. /FEA=mRNA /GEN=KIAA0953 /PROD=KIAA0953 protein /DB_XREF=gi:4589549 /UG=Hs.227850 KIAA0953 protein AB023170 EFR3 homolog B (S. cerevisiae) EFR3B 22979 NM_014971 215329_s_at AL031282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031282 /DEF=Human DNA sequence from clone 283E3 on chromosome 1p36.21-36.33. Contains the alternatively spliced gene for Matrix Metalloproteinase in the Female Reproductive tract MIFR1, -2, MMP2122A, -B and -C, a novel gene, the alternatively spliced CDC2L2 ... /FEA=mRNA_5 /DB_XREF=gi:3860395 /UG=Hs.214291 Human DNA sequence from clone 283E3 on chromosome 1p36.21-36.33. Contains the alternatively spliced gene for Matrix Metalloproteinase in the Female Reproductive tract MIFR1, -2, MMP2122A, -B and -C, a novel gene, the alternatively spliced CDC2L2 gene for AL031282 cyclin-dependent kinase 11A /// cyclin-dependent kinase 11B CDK11A /// CDK11B 984 /// 728642 NM_001291345 /// NM_001787 /// NM_024011 /// NM_033486 /// NM_033487 /// NM_033488 /// NM_033489 /// NM_033490 /// NM_033492 /// NM_033493 /// NM_033527 /// NM_033529 /// NM_033532 /// NM_033534 /// XM_006711061 /// XM_006711062 /// XM_006711063 /// XM_006711064 /// XM_006711065 /// XM_006711066 /// XM_006711067 /// XM_006711068 /// XM_006711069 /// XM_006711070 /// XM_006711071 0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215330_at AL049991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049991.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G222 (from clone DKFZp564G222). /FEA=mRNA /DB_XREF=gi:4884243 /UG=Hs.226103 Homo sapiens mRNA; cDNA DKFZp564G222 (from clone DKFZp564G222) AL049991 215331_at BF062942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062942 /FEA=EST /DB_XREF=gi:10821852 /DB_XREF=est:7h72g02.x1 /CLONE=IMAGE:3321554 /UG=Hs.225968 KIAA1000 protein BF062942 myosin, heavy chain 15 MYH15 22989 NM_014981 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 215332_s_at AW296309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW296309 /FEA=EST /DB_XREF=gi:6702945 /DB_XREF=est:UI-H-BI2-aid-e-11-0-UI.s1 /CLONE=IMAGE:2728821 /UG=Hs.2299 CD8 antigen, beta polypeptide 1 (p37) AW296309 CD8b molecule /// putative T-cell surface glycoprotein CD8 beta-2 chain-like CD8B /// LOC100996919 926 /// 100996919 NM_001178100 /// NM_004931 /// NM_172099 /// NM_172101 /// NM_172102 /// NM_172213 /// XM_003846653 /// XR_244970 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0042101 // T cell receptor complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // non-traceable author statement /// 0042288 // MHC class I protein binding // non-traceable author statement 215333_x_at X08020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X08020.1 /DEF=Human mRNA for glutathione S-transferase subunit 4 (EC 2.5.1.18). /FEA=mRNA /DB_XREF=gi:31923 /UG=Hs.301961 glutathione S-transferase M4 X08020 glutathione S-transferase mu 1 GSTM1 2944 NM_000561 /// NM_146421 /// XM_005270782 /// XM_005270783 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred by curator /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055119 // relaxation of cardiac muscle // traceable author statement /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 215334_at AB023170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023170.1 /DEF=Homo sapiens mRNA for KIAA0953 protein, partial cds. /FEA=mRNA /GEN=KIAA0953 /PROD=KIAA0953 protein /DB_XREF=gi:4589549 /UG=Hs.227850 KIAA0953 protein AB023170 EFR3 homolog B (S. cerevisiae) EFR3B 22979 NM_014971 0005488 // binding // inferred from electronic annotation 215335_at AL137325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137325.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0835 (from clone DKFZp434M0835). /FEA=mRNA /DB_XREF=gi:6807816 /UG=Hs.274575 Homo sapiens mRNA; cDNA DKFZp434M0835 (from clone DKFZp434M0835) AL137325 CTB-176F20.3 215336_at AK002166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002166.1 /DEF=Homo sapiens cDNA FLJ11304 fis, clone PLACE1009997, weakly similar to Rattus norvegicus A-kinase anchoring protein AKAP 220 mRNA. /FEA=mRNA /DB_XREF=gi:7023877 /UG=Hs.232076 A kinase (PRKA) anchor protein 11 AK002166 A kinase (PRKA) anchor protein 11 AKAP11 11215 NM_016248 /// NM_144490 /// XM_005266247 /// XM_005266248 /// XM_005266249 /// XM_005266250 0035556 // intracellular signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0008157 // protein phosphatase 1 binding // traceable author statement /// 0051018 // protein kinase A binding // traceable author statement 215337_at AK022508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022508.1 /DEF=Homo sapiens cDNA FLJ12446 fis, clone NT2RM1000260, highly similar to Homo sapiens thyroid hormone receptor-associated protein complex component TRAP100 mRNA. /FEA=mRNA /DB_XREF=gi:10433935 /UG=Hs.23106 KIAA0130 gene product AK022508 mediator complex subunit 24 MED24 9862 NM_001079518 /// NM_001267797 /// NM_014815 /// NR_052017 /// XM_005257870 /// XM_005257871 /// XM_005257872 /// XM_005257873 /// XM_005257874 /// XM_006722203 /// XM_006722204 /// XM_006722205 /// XM_006722206 /// XM_006722207 /// XR_429934 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // non-traceable author statement 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 215338_s_at AI688640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688640 /FEA=EST /DB_XREF=gi:4899934 /DB_XREF=est:wd40b07.x1 /CLONE=IMAGE:2330581 /UG=Hs.241493 natural killer-tumor recognition sequence AI688640 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 215339_at AI688640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI688640 /FEA=EST /DB_XREF=gi:4899934 /DB_XREF=est:wd40b07.x1 /CLONE=IMAGE:2330581 /UG=Hs.241493 natural killer-tumor recognition sequence AI688640 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 215340_at L05500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L05500.1 /DEF=Human fetal brain adenylyl cyclase mRNA, 3 end. /FEA=mRNA /PROD=adenylyl cyclase /DB_XREF=gi:349268 /UG=Hs.259768 adenylate cyclase 1 (brain) L05500 adenylate cyclase 1 (brain) ADCY1 107 NM_001281768 /// NM_021116 /// XM_005249584 /// XM_005249585 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215341_at AK027182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027182.1 /DEF=Homo sapiens cDNA: FLJ23529 fis, clone LNG06042. /FEA=mRNA /DB_XREF=gi:10440248 /UG=Hs.246306 hypothetical protein FLJ23529; KIAA1697 protein AK027182 dynein, axonemal, heavy chain 6 DNAH6 1768 NM_001370 /// NM_173645 /// XM_006711956 0001539 // cilium or flagellum-dependent cell motility // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 215342_s_at AB019490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB019490.1 /DEF=Homo sapiens IDN4-GGTR7 mRNA, partial cds. /FEA=mRNA /GEN=IDN4-GGTR7 /DB_XREF=gi:4760540 /UG=Hs.242271 KIAA0471 gene product AB019490 RAB GTPase activating protein 1-like RABGAP1L 9910 NM_001035230 /// NM_001243763 /// NM_001243764 /// NM_001243765 /// NM_014857 /// XM_005245680 /// XM_005245681 /// XM_006711692 /// XM_006711693 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from direct assay 215343_at AF070587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070587.1 /DEF=Homo sapiens clone 24741 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387960 /UG=Hs.25770 Homo sapiens clone 24741 mRNA sequence AF070587 coiled-coil domain containing 88C CCDC88C 440193 NM_001080414 /// XM_005267691 /// XM_005267692 /// XR_429316 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0043621 // protein self-association // inferred from sequence or structural similarity 215344_at AL137325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137325.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0835 (from clone DKFZp434M0835). /FEA=mRNA /DB_XREF=gi:6807816 /UG=Hs.274575 Homo sapiens mRNA; cDNA DKFZp434M0835 (from clone DKFZp434M0835) AL137325 215345_x_at AA310709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA310709 /FEA=EST /DB_XREF=gi:1963058 /DB_XREF=est:EST181521 /UG=Hs.249187 Homo sapiens BAC clone RP11-121A8 from 7p14-p13 AA310709 Homo sapiens cDNA FLJ77147 complete cds, highly similar to Homo sapiens T cell receptor gamma variable 7, mRNA. /// T cell receptor gamma variable 7 (pseudogene) /// AK291611 /// TRGV7 /// TRGV7 215346_at BF664114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF664114 /FEA=EST /DB_XREF=gi:11938009 /DB_XREF=est:602145911F1 /CLONE=IMAGE:4309610 /UG=Hs.25648 tumor necrosis factor receptor superfamily, member 5 BF664114 CD40 molecule, TNF receptor superfamily member 5 CD40 958 NM_001250 /// NM_152854 /// XM_005260617 /// XM_005260618 /// XM_005260619 /// XM_006723889 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043406 // positive regulation of MAP kinase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 215347_at AK001127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001127.1 /DEF=Homo sapiens cDNA FLJ10265 fis, clone HEMBB1001014. /FEA=mRNA /DB_XREF=gi:7022192 /UG=Hs.255369 Homo sapiens cDNA FLJ10265 fis, clone HEMBB1001014 AK001127 215348_at L05500 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L05500.1 /DEF=Human fetal brain adenylyl cyclase mRNA, 3 end. /FEA=mRNA /PROD=adenylyl cyclase /DB_XREF=gi:349268 /UG=Hs.259768 adenylate cyclase 1 (brain) L05500 adenylate cyclase 1 (brain) ADCY1 107 NM_001281768 /// NM_021116 /// XM_005249584 /// XM_005249585 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // non-traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215349_at AK000995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000995.1 /DEF=Homo sapiens cDNA FLJ10133 fis, clone HEMBA1003067. /FEA=mRNA /DB_XREF=gi:7021998 /UG=Hs.272209 Homo sapiens cDNA FLJ10133 fis, clone HEMBA1003067 AK000995 BTB (POZ) domain containing 18 BTBD18 643376 NM_001145101 /// XM_006718664 215350_at AB033088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033088.1 /DEF=Homo sapiens mRNA for KIAA1262 protein, partial cds. /FEA=mRNA /GEN=KIAA1262 /PROD=KIAA1262 protein /DB_XREF=gi:6330956 /UG=Hs.272567 KIAA1262 protein AB033088 spectrin repeat containing, nuclear envelope 1 SYNE1 23345 NM_001099267 /// NM_001134379 /// NM_015293 /// NM_033071 /// NM_133650 /// NM_182961 /// XM_006715407 /// XM_006715408 /// XM_006715409 /// XM_006715410 /// XM_006715411 /// XM_006715412 /// XM_006715413 /// XM_006715414 /// XM_006715415 /// XM_006715416 /// XM_006715417 /// XM_006715418 /// XM_006715419 /// XM_006715420 /// XM_006715421 /// XM_006715422 /// XM_006715423 /// XM_006715424 /// XM_006715425 0006810 // transport // inferred from electronic annotation /// 0006997 // nucleus organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030017 // sarcomere // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity 215351_at BG536504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG536504 /FEA=EST /DB_XREF=gi:13528050 /DB_XREF=est:602564909F1 /CLONE=IMAGE:4689314 /UG=Hs.274518 Homo sapiens mRNA; cDNA DKFZp586O2023 (from clone DKFZp586O2023) BG536504 215352_at AL080068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080068.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J062 (from clone DKFZp564J062). /FEA=mRNA /DB_XREF=gi:5262475 /UG=Hs.272534 Homo sapiens mRNA; cDNA DKFZp564J062 (from clone DKFZp564J062) AL080068 GIMAP1-GIMAP5 readthrough /// GTPase, IMAP family member 5 GIMAP1-GIMAP5 /// GIMAP5 55340 /// 100527949 NM_001199577 /// NM_018384 0001659 // temperature homeostasis // inferred from electronic annotation /// 0002729 // positive regulation of natural killer cell cytokine production // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032831 // positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 215353_at AL080068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080068.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J062 (from clone DKFZp564J062). /FEA=mRNA /DB_XREF=gi:5262475 /UG=Hs.272534 Homo sapiens mRNA; cDNA DKFZp564J062 (from clone DKFZp564J062) AL080068 215354_s_at BC002875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002875.1 /DEF=Homo sapiens, clone IMAGE:3940843, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3940843) /DB_XREF=gi:12804044 /UG=Hs.274149 proline and glutamic acid rich nuclear protein BC002875 proline, glutamate and leucine rich protein 1 PELP1 27043 NM_001278241 /// NM_014389 /// XM_006721503 0006351 // transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215355_at AI686582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI686582 /FEA=EST /DB_XREF=gi:4897876 /DB_XREF=est:tx08e05.x1 /CLONE=IMAGE:2268608 /UG=Hs.283824 Homo sapiens Skn-1ai-like mRNA AI686582 POU class 2 homeobox 3 POU2F3 25833 NM_001244682 /// NM_014352 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation 215356_at AK023134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023134.1 /DEF=Homo sapiens cDNA FLJ13072 fis, clone NT2RP3001844. /FEA=mRNA /DB_XREF=gi:10434916 /UG=Hs.277014 Homo sapiens cDNA FLJ13072 fis, clone NT2RP3001844 AK023134 tudor domain containing 12 TDRD12 91646 NM_001015890 /// NM_001110822 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0009566 // fertilization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215357_s_at Z93241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z93241 /DEF=Human DNA sequence from clone RP1-222E13 on chromosome 22 Contains three novel genes, a Mitochondrial ATP Synthase G Chain (EC 3.6.1.34) pseudogene and the DIA1 gene for diaphorase (NADH) (cytochrome b-5 reductase) (EC 1.6.2.2), ESTs, STSs, GSSs, ... /FEA=mRNA_8 /DB_XREF=gi:4826450 /UG=Hs.278314 hypothetical protein Z93241 polymerase (DNA-directed), delta interacting protein 3 POLDIP3 84271 NM_001278657 /// NM_032311 /// NM_178136 /// NR_103820 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215358_x_at AK026980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026980.1 /DEF=Homo sapiens cDNA: FLJ23327 fis, clone HEP12630, highly similar to HSZNF37 Homo sapiens ZNF37A mRNA for zinc finger protein. /FEA=mRNA /DB_XREF=gi:10439974 /UG=Hs.278064 Homo sapiens cDNA: FLJ23327 fis, clone HEP12630, highly similar to HSZNF37 Homo sapiens ZNF37A mRNA for zinc finger protein AK026980 zinc finger protein 37B, pseudogene ZNF37BP 100129482 NR_026777 215359_x_at AI758888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI758888 /FEA=EST /DB_XREF=gi:5152613 /DB_XREF=est:ty94c12.x1 /CLONE=IMAGE:2286742 /UG=Hs.278480 zinc finger protein 44 (KOX 7) AI758888 zinc finger protein ZnFP12-like /// zinc finger protein 44 LOC101060181 /// ZNF44 51710 /// 101060181 NM_001164276 /// NM_016264 /// XM_003959953 /// XM_003960761 /// XM_003960891 /// XM_005259934 /// XM_005259935 /// XM_006722768 /// XM_006722954 /// XM_006726772 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215360_at AK022063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022063.1 /DEF=Homo sapiens cDNA FLJ12001 fis, clone HEMBB1001535. /FEA=mRNA /DB_XREF=gi:10433383 /UG=Hs.278412 Homo sapiens cDNA FLJ12001 fis, clone HEMBB1001535 AK022063 215361_at AK022242 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022242.1 /DEF=Homo sapiens cDNA FLJ12180 fis, clone MAMMA1000744. /FEA=mRNA /DB_XREF=gi:10433598 /UG=Hs.282466 hypothetical protein FLJ21034 AK022242 dedicator of cytokinesis 5 DOCK5 80005 NM_024940 /// XM_005273650 /// XM_005273651 /// XM_006716402 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity 215362_at AF007143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007143.1 /DEF=Homo sapiens clone 23738 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852620 /UG=Hs.28205 Homo sapiens clone 23738 mRNA sequence AF007143 215363_x_at AW168915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW168915 /FEA=EST /DB_XREF=gi:6400440 /DB_XREF=est:xj15b10.x1 /CLONE=IMAGE:2657275 /UG=Hs.283946 Homo sapiens prostate-specific membrane antigen PSM mRNA, exon 18 alternative splice variant, partial cds AW168915 folate hydrolase (prostate-specific membrane antigen) 1 /// folate hydrolase 1B FOLH1 /// FOLH1B 2346 /// 219595 NM_001014986 /// NM_001193471 /// NM_001193472 /// NM_001193473 /// NM_004476 /// NM_153696 /// XM_005252839 /// XM_006718776 0006508 // proteolysis // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006760 // folic acid-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215364_s_at AB007936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007936.1 /DEF=Homo sapiens mRNA for KIAA0467 protein, partial cds. /FEA=mRNA /GEN=KIAA0467 /PROD=KIAA0467 protein /DB_XREF=gi:3413895 /UG=Hs.301943 KIAA0467 protein AB007936 seizure threshold 2 homolog (mouse) SZT2 23334 NM_001012960 /// NM_001012961 /// NM_015284 /// NM_182518 /// XM_005270686 /// XM_006710501 /// XM_006710502 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from electronic annotation /// 1901668 // regulation of superoxide dismutase activity // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215365_at AK022426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022426.1 /DEF=Homo sapiens cDNA FLJ12364 fis, clone MAMMA1002384. /FEA=mRNA /DB_XREF=gi:10433820 /UG=Hs.287522 Homo sapiens cDNA FLJ12364 fis, clone MAMMA1002384 AK022426 calcium channel, voltage-dependent, beta 2 subunit CACNB2 783 NM_000724 /// NM_001167945 /// NM_201570 /// NM_201571 /// NM_201572 /// NM_201590 /// NM_201593 /// NM_201596 /// NM_201597 /// XM_005252588 /// XM_005252591 /// XM_006717502 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay 215366_at AL353943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353943.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761E0611 (from clone DKFZp761E0611). /FEA=mRNA /GEN=DKFZp761E0611 /PROD=hypothetical protein /DB_XREF=gi:7669982 /UG=Hs.284191 Homo sapiens mRNA; cDNA DKFZp761E0611 (from clone DKFZp761E0611) AL353943 sorting nexin 13 SNX13 23161 NM_015132 /// XM_005249672 /// XM_005249673 /// XM_005249674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 215367_at AB046834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046834.1 /DEF=Homo sapiens mRNA for KIAA1614 protein, partial cds. /FEA=mRNA /GEN=KIAA1614 /PROD=KIAA1614 protein /DB_XREF=gi:10047302 /UG=Hs.287381 KIAA1614 protein AB046834 KIAA1614 KIAA1614 57710 NM_020950 215368_at R78299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R78299 /FEA=EST /DB_XREF=gi:853409 /DB_XREF=est:yi81h12.s1 /CLONE=IMAGE:145703 /UG=Hs.287419 Homo sapiens cDNA FLJ11505 fis, clone HEMBA1002139 R78299 nebulin NEB 4703 NM_001164507 /// NM_001164508 /// NM_001271208 /// NM_004543 /// XM_005246590 /// XM_005246591 /// XM_005246592 /// XM_005246593 /// XM_005246594 /// XM_005246595 /// XM_005246596 /// XM_005246597 /// XM_005246598 /// XM_005246599 /// XM_005246600 /// XM_005246601 /// XM_005246602 /// XM_005246603 /// XM_005246604 /// XM_005246606 /// XM_005246608 /// XM_005246610 /// XM_005246611 /// XM_005246612 /// XM_005246613 /// XM_005246615 /// XM_005246616 /// XM_005246617 /// XM_005246618 /// XM_006712541 /// XM_006712542 0007517 // muscle organ development // traceable author statement /// 0007525 // somatic muscle development // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0030832 // regulation of actin filament length // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 215369_at AU145354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145354 /FEA=EST /DB_XREF=gi:11006875 /DB_XREF=est:AU145354 /CLONE=HEMBA1004606 /UG=Hs.287411 Homo sapiens cDNA FLJ11396 fis, clone HEMBA1000604 AU145354 215370_at AU145394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145394 /FEA=EST /DB_XREF=gi:11006915 /DB_XREF=est:AU145394 /CLONE=HEMBA1004711 /UG=Hs.287438 Homo sapiens cDNA FLJ11669 fis, clone HEMBA1004711 AU145394 215371_at AU147599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147599 /FEA=EST /DB_XREF=gi:11009120 /DB_XREF=est:AU147599 /CLONE=MAMMA1001154 /UG=Hs.287501 Homo sapiens cDNA FLJ12227 fis, clone MAMMA1001154 AU147599 mediator complex subunit 27 MED27 9442 NM_001253881 /// NM_001253882 /// NM_004269 /// XM_005272236 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay 215372_x_at AU146794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146794 /FEA=EST /DB_XREF=gi:11008315 /DB_XREF=est:AU146794 /CLONE=HEMBB1001536 /UG=Hs.287475 Homo sapiens cDNA FLJ12002 fis, clone HEMBB1001536 AU146794 membrane associated guanylate kinase, WW and PDZ domain containing 1 MAGI1 9223 NM_001033057 /// NM_004742 /// NM_015520 /// XM_005265563 /// XM_005265564 /// XM_005265565 /// XM_005265566 /// XM_005265568 /// XM_005265570 /// XM_005265571 /// XM_005265574 /// XM_006713407 /// XM_006713408 /// XM_006713409 /// XM_006713410 /// XM_006713411 /// XM_006713412 /// XM_006713413 /// XM_006713414 0006461 // protein complex assembly // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0070997 // neuron death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0051393 // alpha-actinin binding // inferred from physical interaction 215373_x_at AK022213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022213.1 /DEF=Homo sapiens cDNA FLJ12151 fis, clone MAMMA1000431. /FEA=mRNA /DB_XREF=gi:10433560 /UG=Hs.287493 hypothetical protein FLJ12151 AK022213 215374_at AK024849 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024849.1 /DEF=Homo sapiens cDNA: FLJ21196 fis, clone COL00193. /FEA=mRNA /DB_XREF=gi:10437257 /UG=Hs.287650 Homo sapiens cDNA: FLJ21196 fis, clone COL00193 AK024849 poly(A) polymerase alpha PAPOLA 10914 NM_001252006 /// NM_001252007 /// NM_001293627 /// NM_001293628 /// NM_001293632 /// NM_032632 /// XM_005267280 /// XM_005267281 /// XM_005267282 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043631 // RNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215375_x_at AK023938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023938.1 /DEF=Homo sapiens cDNA FLJ13876 fis, clone THYRO1001401. /FEA=mRNA /DB_XREF=gi:10436033 /UG=Hs.287604 Homo sapiens cDNA FLJ13876 fis, clone THYRO1001401 AK023938 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 215376_at AU147830 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147830 /FEA=EST /DB_XREF=gi:11009351 /DB_XREF=est:AU147830 /CLONE=MAMMA1001818 /UG=Hs.296713 Homo sapiens cDNA FLJ12295 fis, clone MAMMA1001818 AU147830 215377_at AK024129 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024129.1 /DEF=Homo sapiens cDNA FLJ14067 fis, clone HEMBB1001315. /FEA=mRNA /DB_XREF=gi:10436434 /UG=Hs.287619 Homo sapiens cDNA FLJ14067 fis, clone HEMBB1001315 AK024129 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 215378_at AU148255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148255 /FEA=EST /DB_XREF=gi:11009776 /DB_XREF=est:AU148255 /CLONE=MAMMA1003031 /UG=Hs.287627 Homo sapiens cDNA FLJ14151 fis, clone MAMMA1003031 AU148255 215379_x_at AV698647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV698647 /FEA=EST /DB_XREF=gi:10300618 /DB_XREF=est:AV698647 /CLONE=GKCBJC12 /UG=Hs.289110 immunoglobulin lambda joining 3 AV698647 immunoglobulin lambda variable 1-44 IGLV1-44 28823 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215380_s_at AK021779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021779.1 /DEF=Homo sapiens cDNA FLJ11717 fis, clone HEMBA1005241. /FEA=mRNA /DB_XREF=gi:10433033 /UG=Hs.288649 hypothetical protein MGC3077 AK021779 gamma-glutamylcyclotransferase GGCT 79017 NM_001199815 /// NM_001199816 /// NM_001199817 /// NM_024051 /// NR_037669 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003839 // gamma-glutamylcyclotransferase activity // inferred from direct assay /// 0003839 // gamma-glutamylcyclotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 215381_at AK024393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024393.1 /DEF=Homo sapiens cDNA FLJ14331 fis, clone PLACE4000320. /FEA=mRNA /DB_XREF=gi:10436771 /UG=Hs.288569 Homo sapiens cDNA FLJ14331 fis, clone PLACE4000320 AK024393 mechanistic target of rapamycin (serine/threonine kinase) MTOR 2475 NM_004958 /// XM_005263438 /// XM_005263439 /// XR_244786 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0006109 // regulation of carbohydrate metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006950 // response to stress // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007584 // response to nutrient // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010507 // negative regulation of autophagy // inferred from sequence or structural similarity /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016049 // cell growth // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030163 // protein catabolic process // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0031998 // regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032095 // regulation of response to food // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040007 // growth // non-traceable author statement /// 0043200 // response to amino acid // inferred from direct assay /// 0043610 // regulation of carbohydrate utilization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from sequence or structural similarity /// 0031931 // TORC1 complex // inferred from direct assay /// 0031931 // TORC1 complex // inferred from mutant phenotype /// 0031932 // TORC2 complex // inferred from direct assay /// 0070438 // mTOR-FKBP12-rapamycin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001030 // RNA polymerase III type 1 promoter DNA binding // inferred from direct assay /// 0001031 // RNA polymerase III type 2 promoter DNA binding // inferred from direct assay /// 0001032 // RNA polymerase III type 3 promoter DNA binding // inferred from direct assay /// 0001156 // TFIIIC-class transcription factor binding // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 215382_x_at AF206666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF206666.1 /DEF=Homo sapiens mast cell alpha II tryptase mRNA, partial cds, alternatively spliced. /FEA=mRNA /PROD=mast cell alpha II tryptase /DB_XREF=gi:11493899 /UG=Hs.294158 tryptase beta 2 AF206666 tryptase alpha/beta 1 TPSAB1 7177 NM_003294 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 215383_x_at AL137312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137312.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761K23121 (from clone DKFZp761K23121). /FEA=mRNA /DB_XREF=gi:6807797 /UG=Hs.293681 Homo sapiens mRNA; cDNA DKFZp761K23121 (from clone DKFZp761K23121) AL137312 spastic paraplegia 21 (autosomal recessive, Mast syndrome) SPG21 51324 NM_001127889 /// NM_001127890 /// NM_016630 /// XM_005254436 /// XM_005254437 /// XM_006720564 0008219 // cell death // inferred from electronic annotation /// 0050851 // antigen receptor-mediated signaling pathway // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay 0042609 // CD4 receptor binding // inferred from physical interaction 215384_s_at AF095910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF095910.1 /DEF=Homo sapiens microtubule-associated protein 1A like protein (M1LP) mRNA, partial cds. /FEA=mRNA /GEN=M1LP /PROD=microtubule-associated protein 1A like protein /DB_XREF=gi:6093303 /UG=Hs.301916 Homo sapiens microtubule-associated protein 1A like protein (M1LP) mRNA, partial cds AF095910 microtubule-associated protein 1A MAP1A 4130 NM_002373 /// XM_005254385 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215385_at AK022473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022473.1 /DEF=Homo sapiens cDNA FLJ12411 fis, clone MAMMA1002964. /FEA=mRNA /DB_XREF=gi:10433882 /UG=Hs.296722 Homo sapiens cDNA FLJ12411 fis, clone MAMMA1002964 AK022473 215386_at AU148161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148161 /FEA=EST /DB_XREF=gi:11009682 /DB_XREF=est:AU148161 /CLONE=MAMMA1002758 /UG=Hs.296720 Homo sapiens cDNA FLJ12396 fis, clone MAMMA1002758 AU148161 215387_x_at AK021505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021505.1 /DEF=Homo sapiens cDNA FLJ11443 fis, clone HEMBA1001330. /FEA=mRNA /DB_XREF=gi:10432701 /UG=Hs.297945 Homo sapiens cDNA FLJ11443 fis, clone HEMBA1001330 AK021505 215388_s_at X56210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X56210.1 /DEF=H.sapiens mRNA for complement Factor H-related protein 1, clone H 36-2. /FEA=mRNA /GEN=H 36-2 /PROD=FHR-1; complement Factor H-related protein 1 /DB_XREF=gi:30132 /UG=Hs.296941 H factor (complement)-like 2 X56210 complement factor H /// complement factor H-related 1 CFH /// CFHR1 3075 /// 3078 NM_000186 /// NM_001014975 /// NM_002113 /// XM_006711282 /// XM_006711283 /// XM_006711284 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay 215389_s_at X79857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79857.1 /DEF=H.sapiens HTNT4 mRNA for cardiac troponin T. /FEA=mRNA /PROD=troponin T /DB_XREF=gi:587431 /UG=Hs.296865 troponin T2, cardiac X79857 troponin T type 2 (cardiac) TNNT2 7139 NM_000364 /// NM_001001430 /// NM_001001431 /// NM_001001432 /// NM_001276345 /// NM_001276346 /// NM_001276347 /// XM_006711508 /// XM_006711509 /// XM_006711510 /// XM_006711511 /// XM_006711512 /// XM_006711513 /// XM_006711514 0006200 // ATP catabolic process // inferred from direct assay /// 0006936 // muscle contraction // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0030049 // muscle filament sliding // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0051592 // response to calcium ion // inferred from mutant phenotype /// 0055009 // atrial cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005861 // troponin complex // inferred from direct assay /// 0005865 // striated muscle thin filament // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement 0003779 // actin binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0030172 // troponin C binding // inferred from physical interaction /// 0031013 // troponin I binding // inferred from physical interaction 215390_at AU147194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147194 /FEA=EST /DB_XREF=gi:11008715 /DB_XREF=est:AU147194 /CLONE=HEMBB1002684 /UG=Hs.300978 Homo sapiens cDNA FLJ12102 fis, clone HEMBB1002684 AU147194 215391_at AA633627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA633627 /FEA=EST /DB_XREF=gi:2556841 /DB_XREF=est:ae66e03.s1 /CLONE=IMAGE:969148 /UG=Hs.301916 Homo sapiens microtubule-associated protein 1A like protein (M1LP) mRNA, partial cds AA633627 microtubule-associated protein 1A MAP1A 4130 NM_002373 /// XM_005254385 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215392_at AU148154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148154 /FEA=EST /DB_XREF=gi:11009675 /DB_XREF=est:AU148154 /CLONE=MAMMA1002744 /UG=Hs.298014 Homo sapiens cDNA FLJ14136 fis, clone MAMMA1002744 AU148154 215393_s_at AK002054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002054.1 /DEF=Homo sapiens cDNA FLJ11192 fis, clone PLACE1007618, highly similar to Homo sapiens mRNA for KIAA0977 protein. /FEA=mRNA /DB_XREF=gi:7023704 /UG=Hs.301634 Homo sapiens cDNA FLJ11192 fis, clone PLACE1007618, highly similar to Homo sapiens mRNA for KIAA0977 protein AK002054 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 215394_at AU148957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148957 /FEA=EST /DB_XREF=gi:11010478 /DB_XREF=est:AU148957 /CLONE=NT2RM4001313 /UG=Hs.306638 Homo sapiens cDNA FLJ12591 fis, clone NT2RM4001313, moderately similar to PHOSPHATIDYLINOSITOL 3-KINASE VPS34-LIKE (EC 2.7.1.137) AU148957 phosphatidylinositol 3-kinase, catalytic subunit type 3 PIK3C3 5289 NM_002647 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043201 // response to leucine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // inferred from electronic annotation 215395_x_at U66061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U66061 /DEF=Human germline T-cell receptor beta chain TCRBV17S1A1T, TCRBV2S1, TCRBV10S1P, TCRBV29S1P, TCRBV19S1P, TCRBV15S1, TCRBV11S1A1T, HVB relic, TCRBV28S1P, TCRBV34S1, TCRBV14S1, TCRBV3S1, TCRBV4S1A1T, TRY4, TRY5, TRY6, TRY7, TRY8, TCRBD1, TCRBJ1S1, TCRB... /FEA=CDS_1 /DB_XREF=gi:1552511 /UG=Hs.302180 Human germline T-cell receptor beta chain TCRBV17S1A1T, TCRBV2S1, TCRBV10S1P, TCRBV29S1P, TCRBV19S1P, TCRBV15S1, TCRBV11S1A1T, HVB relic, TCRBV28S1P, TCRBV34S1, TCRBV14S1, TCRBV3S1, TCRBV4S1A1T, TRY4, TRY5, TRY6, TRY7, TRY8, TCRBD1, TCRBJ1S1, TCRBJ1S2, TC U66061 protease, serine, 3 pseudogene 2 PRSS3P2 154754 NR_001296 0006508 // proteolysis // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215396_at AB014586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014586.1 /DEF=Homo sapiens mRNA for KIAA0686 protein, partial cds. /FEA=mRNA /GEN=KIAA0686 /PROD=KIAA0686 protein /DB_XREF=gi:3327185 /UG=Hs.306181 KIAA0686 protein AB014586 G protein-coupled receptor 98 GPR98 84059 NM_032119 /// NR_003149 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0060122 // inner ear receptor stereocilium organization // inferred from electronic annotation 0002142 // stereocilia ankle link complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation 215397_x_at AU148086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148086 /FEA=EST /DB_XREF=gi:11009607 /DB_XREF=est:AU148086 /CLONE=MAMMA1002554 /UG=Hs.302691 Homo sapiens cDNA FLJ12379 fis, clone MAMMA1002554 AU148086 215398_at AF038194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF038194.1 /DEF=Homo sapiens clone 23821 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2795914 /UG=Hs.302182 Homo sapiens clone 23821 mRNA sequence AF038194 215399_s_at AI683900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI683900 /FEA=EST /DB_XREF=gi:4894082 /DB_XREF=est:tw54e04.x1 /CLONE=IMAGE:2263518 /UG=Hs.76228 amplified in osteosarcoma AI683900 osteosarcoma amplified 9, endoplasmic reticulum lectin OS9 10956 NM_001017956 /// NM_001017957 /// NM_001017958 /// NM_001261420 /// NM_001261421 /// NM_001261422 /// NM_001261423 /// NM_006812 /// XM_005268581 /// XM_006719200 /// XM_006719201 0006605 // protein targeting // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000836 // Hrd1p ubiquitin ligase complex // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215400_x_at AU146952 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146952 /FEA=EST /DB_XREF=gi:11008473 /DB_XREF=est:AU146952 /CLONE=HEMBB1001962 /UG=Hs.306624 Homo sapiens cDNA FLJ12046 fis, clone HEMBB1001962 AU146952 adenylate cyclase 9 ADCY9 115 NM_001116 /// XM_005255079 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215401_at AU147698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147698 /FEA=EST /DB_XREF=gi:11009219 /DB_XREF=est:AU147698 /CLONE=MAMMA1001408 /UG=Hs.306633 Homo sapiens cDNA FLJ12248 fis, clone MAMMA1001408 AU147698 215402_at AL157428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157428.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761F152 (from clone DKFZp761F152). /FEA=mRNA /DB_XREF=gi:7018458 /UG=Hs.306479 Homo sapiens mRNA; cDNA DKFZp761F152 (from clone DKFZp761F152) AL157428 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215403_at AK024860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024860.1 /DEF=Homo sapiens cDNA: FLJ21207 fis, clone COL00362. /FEA=mRNA /DB_XREF=gi:10437268 /UG=Hs.306708 Homo sapiens cDNA: FLJ21207 fis, clone COL00362 AK024860 215404_x_at AK024388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024388.1 /DEF=Homo sapiens cDNA FLJ14326 fis, clone PLACE4000247. /FEA=mRNA /DB_XREF=gi:10436762 /UG=Hs.306678 Homo sapiens cDNA FLJ14326 fis, clone PLACE4000247 AK024388 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 215405_at AK025072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025072.1 /DEF=Homo sapiens cDNA: FLJ21419 fis, clone COL04084. /FEA=mRNA /DB_XREF=gi:10437512 /UG=Hs.306759 Homo sapiens cDNA: FLJ21419 fis, clone COL04084 AK025072 215406_at AK024860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024860.1 /DEF=Homo sapiens cDNA: FLJ21207 fis, clone COL00362. /FEA=mRNA /DB_XREF=gi:10437268 /UG=Hs.306708 Homo sapiens cDNA: FLJ21207 fis, clone COL00362 AK024860 215407_s_at AK024064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024064.1 /DEF=Homo sapiens cDNA FLJ14002 fis, clone Y79AA1002307, highly similar to Homo sapiens astrotactin2 (ASTN2) mRNA. /FEA=mRNA /DB_XREF=gi:10436343 /UG=Hs.30898 KIAA0634 protein AK024064 astrotactin 2 ASTN2 23245 NM_001184734 /// NM_001184735 /// NM_014010 /// NM_198186 /// NM_198187 /// NM_198188 2000009 // negative regulation of protein localization to cell surface // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0060187 // cell pole // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215408_at AK025072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025072.1 /DEF=Homo sapiens cDNA: FLJ21419 fis, clone COL04084. /FEA=mRNA /DB_XREF=gi:10437512 /UG=Hs.306759 Homo sapiens cDNA: FLJ21419 fis, clone COL04084 AK025072 215409_at BG255923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG255923 /FEA=EST /DB_XREF=gi:12765739 /DB_XREF=est:602367576F1 /CLONE=IMAGE:4475586 /UG=Hs.321149 hypothetical protein FLJ10257 BG255923 lysophosphatidylcholine acyltransferase 4 LPCAT4 254531 NM_153613 /// XM_006720454 /// XR_243087 /// XR_243088 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047166 // 1-alkenylglycerophosphoethanolamine O-acyltransferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047192 // 1-alkylglycerophosphocholine O-acetyltransferase activity // inferred from electronic annotation /// 0071617 // lysophospholipid acyltransferase activity // inferred from direct assay /// 0071617 // lysophospholipid acyltransferase activity // inferred from mutant phenotype 215410_at AB017005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB017005.1 /DEF=Homo sapiens PMS2L14 mRNA, partial cds. /FEA=mRNA /GEN=PMS2L14 /DB_XREF=gi:4239951 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 AB017005 postmeiotic segregation increased 2 pseudogene /// postmeiotic segregation increased 2 pseudogene 1 /// postmeiotic segregation increased 2 pseudogene 4 /// postmeiotic segregation increased 2 pseudogene 5 /// postmeiotic segregation increased 2 pseudogene 6 /// postmeiotic segregation increased 2 pseudogene 9 LOC441259 /// PMS2P1 /// PMS2P4 /// PMS2P5 /// PMS2P6 /// PMS2P9 5379 /// 5382 /// 5383 /// 441259 /// 729453 /// 100132832 NM_001129851 /// NM_005394 /// NM_174930 /// NR_003613 /// NR_022007 /// NR_027775 /// NR_027776 /// NR_027777 /// NR_028058 /// NR_046297 /// NR_046299 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 215411_s_at AL008730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL008730 /DEF=Human DNA sequence from PAC 487J7 on chromosome 6q21-22.1. Contains an unknown gene coding for three alternative mRNAs. Contains ESTs, STSs, a BAC end-sequence (GSS) and a CA repeat polymorphism /FEA=mRNA_3 /DB_XREF=gi:2842415 /UG=Hs.7446 DKFZP586G0522 protein AL008730 TRAF3 interacting protein 2 TRAF3IP2 10758 NM_001164281 /// NM_001164282 /// NM_001164283 /// NM_147200 /// NM_147686 /// NR_028338 /// XM_006715319 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0048305 // immunoglobulin secretion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 215412_x_at AB017007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB017007.1 /DEF=Homo sapiens PMS2L16 mRNA, partial cds. /FEA=mRNA /GEN=PMS2L16 /DB_XREF=gi:4239955 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 AB017007 postmeiotic segregation increased 2 pseudogene 8 PMS2P8 729299 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 215413_at AK023832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023832.1 /DEF=Homo sapiens cDNA FLJ13770 fis, clone PLACE4000269, highly similar to Rattus norvegicus rexo70 mRNA. /FEA=mRNA /DB_XREF=gi:10435886 /UG=Hs.325530 KIAA1067 protein AK023832 exocyst complex component 7 EXOC7 23265 NM_001013839 /// NM_001145297 /// NM_001145298 /// NM_001145299 /// NM_001282313 /// NM_001282314 /// NM_015219 /// XM_006721786 /// XM_006721787 /// XM_006721788 /// XM_006721789 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215414_at AI524687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI524687 /FEA=EST /DB_XREF=gi:4438822 /DB_XREF=est:th12a07.x1 /CLONE=IMAGE:2118036 /UG=Hs.57969 phenylalanine-tRNA synthetase AI524687 phenylalanyl-tRNA synthetase 2, mitochondrial FARS2 10667 NM_006567 /// XM_005248811 /// XM_005248812 /// XM_005248813 /// XM_005248814 /// XM_006714966 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 215415_s_at U70064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U70064.1 /DEF=Human lysosomal trafficking regulator (LYST) mRNA, partial cds. /FEA=mRNA /GEN=LYST /PROD=lysosomal trafficking regulator /DB_XREF=gi:1806625 /UG=Hs.36508 Chediak-Higashi syndrome 1 U70064 lysosomal trafficking regulator LYST 1130 NM_000081 /// NM_001005736 /// NR_102436 /// XM_005273027 /// XM_005273028 /// XM_005273029 /// XM_005273030 /// XM_006711731 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from sequence or structural similarity /// 0032438 // melanosome organization // inferred from sequence or structural similarity /// 0032510 // endosome to lysosome transport via multivesicular body sorting pathway // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215416_s_at AC004472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004472 /DEF=Homo sapiens chromosome 9, P1 clone 11659 /FEA=CDS_5 /DB_XREF=gi:2984582 /UG=Hs.3439 stomatin-like 2 AC004472 stomatin (EPB72)-like 2 STOML2 30968 NM_001287031 /// NM_001287032 /// NM_001287033 /// NM_013442 0006851 // mitochondrial calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0010876 // lipid localization // inferred from sequence or structural similarity /// 0010918 // positive regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0032623 // interleukin-2 production // inferred from sequence or structural similarity /// 0034982 // mitochondrial protein processing // inferred from sequence or structural similarity /// 0035710 // CD4-positive, alpha-beta T cell activation // inferred from sequence or structural similarity /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0090297 // positive regulation of mitochondrial DNA replication // inferred from mutant phenotype /// 1900210 // positive regulation of cardiolipin metabolic process // inferred from mutant phenotype /// 1990046 // stress-induced mitochondrial fusion // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0042101 // T cell receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 1901612 // cardiolipin binding // inferred from direct assay 215417_at AI803703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803703 /FEA=EST /DB_XREF=gi:5369175 /DB_XREF=est:tc19f04.x1 /CLONE=IMAGE:2064319 /UG=Hs.44175 KIAA0919 protein AI803703 exocyst complex component 6B EXOC6B 23233 NM_015189 /// XM_005264223 /// XM_005264224 /// XM_006711970 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation 215418_at AK022316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022316.1 /DEF=Homo sapiens cDNA FLJ12254 fis, clone MAMMA1001465. /FEA=mRNA /DB_XREF=gi:10433685 /UG=Hs.44077 alpha-parvin AK022316 parvin, alpha PARVA 55742 NM_018222 /// XM_005253015 0001525 // angiogenesis // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0070252 // actin-mediated cell contraction // inferred from sequence or structural similarity /// 0071670 // smooth muscle cell chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215419_at AB029009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029009.1 /DEF=Homo sapiens mRNA for KIAA1086 protein, partial cds. /FEA=mRNA /GEN=KIAA1086 /PROD=KIAA1086 protein /DB_XREF=gi:5689508 /UG=Hs.65750 KIAA1086 protein AB029009 zinc finger RNA binding protein 2 ZFR2 23217 NM_001145640 /// NM_015174 /// NR_027149 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215420_at BE869172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE869172 /FEA=EST /DB_XREF=gi:10317948 /DB_XREF=est:601445161F1 /CLONE=IMAGE:3849303 /UG=Hs.69351 Indian hedgehog (Drosophila) homolog BE869172 indian hedgehog IHH 3549 NM_002181 0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0003406 // retinal pigment epithelium development // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016539 // intein-mediated protein splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030704 // vitelline membrane formation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033085 // negative regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from sequence or structural similarity /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0046639 // negative regulation of alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0048074 // negative regulation of eye pigmentation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060220 // camera-type eye photoreceptor cell fate commitment // inferred from electronic annotation /// 0060323 // head morphogenesis // inferred from electronic annotation /// 0061053 // somite development // inferred from sequence or structural similarity /// 0072498 // embryonic skeletal joint development // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005113 // patched binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215421_at AI821657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI821657 /FEA=EST /DB_XREF=gi:5440736 /DB_XREF=est:zv41a09.x5 /CLONE=IMAGE:756184 /UG=Hs.66163 Homo sapiens clone 23636 mRNA sequence AI821657 uncharacterized LOC100131510 LOC100131510 100131510 XR_109960 /// XR_112306 /// XR_171284 215422_at AA757368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA757368 /FEA=EST /DB_XREF=gi:2805231 /DB_XREF=est:ah98a10.s1 /CLONE=IMAGE:1327098 /UG=Hs.7057 Homo sapiens Cri-du-chat region mRNA, clone NIBB11 AA757368 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215423_at U52827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U52827.1 /DEF=Homo sapiens Cri-du-chat region mRNA, clone NIBB11. /FEA=mRNA /DB_XREF=gi:1354448 /UG=Hs.7057 Homo sapiens Cri-du-chat region mRNA, clone NIBB11 U52827 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215424_s_at AV689564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV689564 /FEA=EST /DB_XREF=gi:10291427 /DB_XREF=est:AV689564 /CLONE=GKCEAA06 /UG=Hs.79008 SKI-INTERACTING PROTEIN AV689564 SNW domain containing 1 SNW1 22938 NM_012245 /// XM_005267413 /// XM_005267414 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048385 // regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0070564 // positive regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071146 // SMAD3-SMAD4 protein complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay 215425_at AL049332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049332.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564L176 (from clone DKFZp564L176). /FEA=mRNA /DB_XREF=gi:4500108 /UG=Hs.77311 BTG family, member 3 AL049332 BTG family, member 3 BTG3 10950 NM_001130914 /// NM_006806 /// XM_006723963 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215426_at AL117532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117532.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E192 (from clone DKFZp434E192); partial cds. /FEA=mRNA /GEN=DKFZp434E192 /PROD=hypothetical protein /DB_XREF=gi:5912059 /UG=Hs.81505 KIAA0579 protein AL117532 zinc finger, CCHC domain containing 14 ZCCHC14 23174 NM_015144 /// XM_005255858 /// XR_243401 0007154 // cell communication // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215427_s_at AL117532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117532.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E192 (from clone DKFZp434E192); partial cds. /FEA=mRNA /GEN=DKFZp434E192 /PROD=hypothetical protein /DB_XREF=gi:5912059 /UG=Hs.81505 KIAA0579 protein AL117532 zinc finger, CCHC domain containing 14 ZCCHC14 23174 NM_015144 /// XM_005255858 /// XR_243401 0007154 // cell communication // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215428_at AL109707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109707.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 295344. /FEA=mRNA /DB_XREF=gi:5689824 /UG=Hs.94327 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 295344 AL109707 RP11-680F8.4 215429_s_at BE045982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE045982 /FEA=EST /DB_XREF=gi:8363035 /DB_XREF=est:hd91b04.x4 /CLONE=IMAGE:2916847 /UG=Hs.99093 Homo sapiens chromosome 19, cosmid R28379 BE045982 zinc finger protein 428 ZNF428 126299 NM_182498 /// XM_005258517 0046872 // metal ion binding // inferred from electronic annotation 215430_at AA757089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA757089 /FEA=EST /DB_XREF=gi:2804952 /DB_XREF=est:ah55e05.s1 /CLONE=1309568 /UG=Hs.98008 H.sapiens mRNA for glycerol kinase testis specific 2 AA757089 glycerol kinase 2 GK2 2712 NM_033214 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // non-traceable author statement /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019563 // glycerol catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 215431_at AI033054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI033054 /FEA=EST /DB_XREF=gi:3254007 /DB_XREF=est:ow93d11.s1 /CLONE=IMAGE:1654389 /UG=Hs.95011 syntrophin, beta 1 (dystrophin-associated protein A1, 59kD, basic component 1) AI033054 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) SNTB1 6641 NM_021021 /// XM_005251031 /// XM_005251032 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation 215432_at AC003034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003034 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-923A4 /FEA=mRNA_2 /DB_XREF=gi:3219338 /UG=Hs.98732 Homo sapiens Chromosome 16 BAC clone CIT987SK-A-923A4 AC003034 acyl-CoA synthetase medium-chain family member 1 ACSM1 116285 NM_052956 /// XM_005255084 /// XM_005255086 /// XM_006721016 /// XM_006721017 /// XM_006721018 /// XR_243258 /// XR_429672 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015980 // energy derivation by oxidation of organic compounds // non-traceable author statement /// 0018874 // benzoate metabolic process // non-traceable author statement /// 0019395 // fatty acid oxidation // non-traceable author statement /// 0019605 // butyrate metabolic process // non-traceable author statement /// 0042632 // cholesterol homeostasis // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003996 // acyl-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015645 // fatty acid ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from direct assay 215433_at BF447983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF447983 /FEA=EST /DB_XREF=gi:11513212 /DB_XREF=est:hr83f09.x1 /CLONE=IMAGE:3135113 /UG=Hs.58993 Homo sapiens mRNA sequence, IMAGE clone 417820 BF447983 Homo sapiens mRNA sequence, IMAGE clone 417820. /// dpy-19-like 1 (C. elegans) AJ011981 /// DPY19L1 23333 NM_015283 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 215434_x_at AV684285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV684285 /FEA=EST /DB_XREF=gi:10286148 /DB_XREF=est:AV684285 /CLONE=GKCENE06 /UG=Hs.323463 KIAA1693 protein; hypothetical protein FLJ20719 AV684285 neuroblastoma breakpoint family member 1-like /// neuroblastoma breakpoint family, member 1 /// neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 19 /// neuroblastoma breakpoint family, member 26 LOC102724250 /// NBPF1 /// NBPF10 /// NBPF11 /// NBPF14 /// NBPF15 /// NBPF19 /// NBPF26 25832 /// 55672 /// 200030 /// 284565 /// 100132406 /// 101060226 /// 101060684 /// 102724250 NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_001170755 /// NM_015383 /// NM_017940 /// NM_173638 /// NM_183372 /// NR_046188 /// NR_110864 /// XM_003960069 /// XM_003960230 /// XM_005245096 /// XM_005245097 /// XM_005276139 /// XM_005276140 /// XM_005276167 /// XM_005276168 /// XM_005276169 /// XM_005276170 /// XM_005276171 /// XM_005276172 /// XM_005276173 /// XM_005276174 /// XM_005276175 /// XM_005276176 /// XM_005276177 /// XM_005276178 /// XM_005276179 /// XM_005276180 /// XM_005276181 /// XM_005276182 /// XM_005276183 /// XM_005276184 /// XM_005276185 /// XM_005276186 /// XM_005276187 /// XM_005277469 /// XM_005277470 /// XM_005277471 /// XM_005277472 /// XM_005277473 /// XM_005277474 /// XM_005277475 /// XM_005277476 /// XM_005277477 /// XM_005277478 /// XM_005277479 /// XM_005277480 /// XM_005277481 /// XM_005277482 /// XM_005277483 /// XM_005277484 /// XM_005277485 /// XM_005277486 /// XM_005277487 /// XM_005277488 /// XM_005277503 /// XM_005277504 /// XM_005277505 /// XM_006710234 /// XM_006711091 /// XM_006711092 /// XM_006711093 /// XM_006711094 /// XM_006711095 /// XM_006711096 /// XM_006711197 /// XM_006711265 /// XM_006711707 /// XM_006711708 /// XM_006711709 /// XM_006711710 /// XM_006711711 /// XM_006711712 /// XM_006724882 /// XM_006724883 /// XM_006724884 /// XM_006724885 /// XM_006724886 /// XM_006724887 /// XM_006724888 /// XM_006724889 /// XM_006724890 /// XM_006724891 /// XM_006724892 /// XM_006724893 /// XM_006724894 /// XM_006726340 /// XM_006726341 /// XM_006726342 /// XM_006726343 /// XM_006726344 /// XM_006726345 /// XM_006726360 /// XM_006726361 /// XM_006726362 /// XM_006726363 /// XM_006726364 /// XM_006726365 /// XR_426769 /// XR_430573 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 215435_at AK021983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021983.1 /DEF=Homo sapiens cDNA FLJ11921 fis, clone HEMBB1000318. /FEA=mRNA /DB_XREF=gi:10433292 /UG=Hs.306616 Homo sapiens cDNA FLJ11921 fis, clone HEMBB1000318 AK021983 215436_at AK023959 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023959.1 /DEF=Homo sapiens cDNA FLJ13897 fis, clone THYRO1001706. /FEA=mRNA /DB_XREF=gi:10436079 /UG=Hs.301488 Homo sapiens cDNA FLJ13897 fis, clone THYRO1001706 AK023959 hydroxysteroid dehydrogenase like 2 HSDL2 84263 NM_001195822 /// NM_032303 /// NR_036651 /// XM_006717303 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 215437_x_at BE513659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE513659 /FEA=EST /DB_XREF=gi:9720871 /DB_XREF=est:601316082F1 /CLONE=IMAGE:3634533 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A BE513659 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 215438_x_at BE906054 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE906054 /FEA=EST /DB_XREF=gi:10399395 /DB_XREF=est:601497073F1 /CLONE=IMAGE:3899034 /UG=Hs.2707 G1 to S phase transition 1 BE906054 G1 to S phase transition 1 GSPT1 2935 NM_001130006 /// NM_001130007 /// NM_002094 /// XM_005255274 /// XM_005255275 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from mutant phenotype /// 0006479 // protein methylation // inferred from direct assay 0005622 // intracellular // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003747 // translation release factor activity // inferred from mutant phenotype /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215439_x_at AU146391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146391 /FEA=EST /DB_XREF=gi:11007912 /DB_XREF=est:AU146391 /CLONE=HEMBB1000343 /UG=Hs.209806 Homo sapiens cDNA FLJ11924 fis, clone HEMBB1000343 AU146391 215440_s_at AL523320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523320 /FEA=EST /DB_XREF=gi:12786813 /DB_XREF=est:AL523320 /CLONE=CS0DC001YD02 (5 prime) /UG=Hs.184736 hypothetical protein FLJ10097 AL523320 brain expressed, X-linked 4 BEX4 56271 NM_001080425 /// NM_001127688 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 215441_at U79301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79301.1 /DEF=Human clone 23842 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710286 /UG=Hs.135617 Human clone 23842 mRNA sequence U79301 215442_s_at BE740743 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE740743 /FEA=EST /DB_XREF=gi:10154735 /DB_XREF=est:601593529F1 /CLONE=IMAGE:3947599 /UG=Hs.123078 thyroid stimulating hormone receptor BE740743 thyroid stimulating hormone receptor TSHR 7253 NM_000369 /// NM_001018036 /// NM_001142626 /// XM_005268037 /// XM_005268039 /// XM_006720245 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004996 // thyroid-stimulating hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 215443_at BE740743 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE740743 /FEA=EST /DB_XREF=gi:10154735 /DB_XREF=est:601593529F1 /CLONE=IMAGE:3947599 /UG=Hs.123078 thyroid stimulating hormone receptor BE740743 thyroid stimulating hormone receptor TSHR 7253 NM_000369 /// NM_001018036 /// NM_001142626 /// XM_005268037 /// XM_005268039 /// XM_006720245 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // inferred from electronic annotation /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0040012 // regulation of locomotion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004996 // thyroid-stimulating hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 215444_s_at X81006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81006.1 /DEF=H.sapiens HCG I mRNA. /FEA=mRNA /DB_XREF=gi:531406 /UG=Hs.104114 HCGI protein X81006 tripartite motif containing 31 TRIM31 11074 NM_007028 /// NM_052816 /// XM_006714977 /// XM_006714978 /// XM_006725470 /// XM_006725685 /// XM_006725686 /// XM_006725687 /// XM_006725804 /// XM_006725805 /// XM_006725806 /// XM_006725894 /// XM_006725895 /// XM_006725983 /// XM_006725984 /// XM_006726074 /// XM_006726075 /// XR_427824 /// XR_430855 /// XR_430933 /// XR_430971 /// XR_430994 /// XR_430995 /// XR_431012 /// XR_431041 /// XR_431042 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215445_x_at AF007136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007136.1 /DEF=Homo sapiens clone 23605 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852611 /UG=Hs.100516 Homo sapiens clone 23605 mRNA sequence AF007136 215446_s_at L16895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L16895 /DEF=Human lysyl oxidase (LOX) gene, exon 7 /FEA=mRNA /DB_XREF=gi:292923 /UG=Hs.102267 lysyl oxidase L16895 lysyl oxidase LOX 4015 NM_001178102 /// NM_002317 0001568 // blood vessel development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0004720 // protein-lysine 6-oxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215447_at AL080215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080215.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J0323 (from clone DKFZp586J0323). /FEA=mRNA /DB_XREF=gi:5262706 /UG=Hs.102301 Homo sapiens mRNA; cDNA DKFZp586J0323 (from clone DKFZp586J0323) AL080215 215448_at AF035290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035290.1 /DEF=Homo sapiens clone 23556 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661044 /UG=Hs.106300 Homo sapiens clone 23556 mRNA sequence AF035290 215449_at AI052224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI052224 /FEA=EST /DB_XREF=gi:3308215 /DB_XREF=est:oz21a02.x1 /CLONE=IMAGE:1675946 /UG=Hs.132724 Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine recepto AI052224 translocator protein 2 TSPO2 222642 NM_001010873 /// NM_001159726 0006810 // transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015485 // cholesterol binding // inferred from sequence or structural similarity 215450_at W87901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87901 /FEA=EST /DB_XREF=gi:1401985 /DB_XREF=est:zh66f04.r1 /CLONE=IMAGE:417055 /UG=Hs.1066 small nuclear ribonucleoprotein polypeptide E W87901 small nuclear ribonucleoprotein polypeptide E SNRPE 6635 NM_003094 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0042633 // hair cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // non-traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215451_s_at BF575588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF575588 /FEA=EST /DB_XREF=gi:11649222 /DB_XREF=est:602133573F1 /CLONE=IMAGE:4288435 /UG=Hs.114765 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 BF575588 AF4/FMR2 family, member 1 AFF1 4299 NM_001166693 /// NM_005935 /// XM_005263007 /// XM_005263008 /// XM_005263009 /// XM_005263010 /// XM_005263011 /// XM_005263012 /// XM_005263013 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215452_x_at AL031133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031133 /DEF=Human DNA sequence from clone 281H8 on chromosome 6q25.1-25.3. Contains up to four novel genes, one with similarity to KIAA0323 and worm C30F12.1 and another with Ubiquitin-Like protein gene SMT3 (the latter in an intron of a novel gene). Contains... /FEA=mRNA_2 /DB_XREF=gi:3676189 /UG=Hs.113293 Human DNA sequence from clone 281H8 on chromosome 6q25.1-25.3. Contains up to four novel genes, one with similarity to KIAA0323 and worm C30F12.1 and another with Ubiquitin-Like protein gene SMT3 (the latter in an intron of a novel gene). Contains ESTs, S AL031133 small ubiquitin-like modifier 4 SUMO4 387082 NM_001002255 0016925 // protein sumoylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215454_x_at AI831055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI831055 /FEA=EST /DB_XREF=gi:5451726 /DB_XREF=est:wj62c08.x1 /CLONE=IMAGE:2407406 /UG=Hs.1074 surfactant, pulmonary-associated protein C AI831055 surfactant protein C SFTPC 6440 NM_001172357 /// NM_001172410 /// NM_003018 /// XM_005273598 /// XM_006716379 /// XM_006716380 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070741 // response to interleukin-6 // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071732 // cellular response to nitric oxide // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 215455_at AK000721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000721.1 /DEF=Homo sapiens cDNA FLJ20714 fis, clone HUV00275, highly similar to AF098162 Homo sapiens timeless homolog mRNA. /FEA=mRNA /DB_XREF=gi:7020985 /UG=Hs.118631 timeless (Drosophila) homolog AK000721 timeless circadian clock TIMELESS 8914 NM_003920 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215456_at AF070625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070625.1 /DEF=Homo sapiens clone 24734 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283891 /UG=Hs.12440 Homo sapiens clone 24734 mRNA sequence AF070625 215457_at AF070647 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070647.1 /DEF=Homo sapiens clone 24438 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283921 /UG=Hs.124126 Homo sapiens clone 24438 mRNA sequence AF070647 215458_s_at AF199364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF199364.2 /DEF=Homo sapiens E3 ubiquitin ligase SMURF1 mRNA, partial cds. /FEA=mRNA /PROD=E3 ubiquitin ligase SMURF1 /DB_XREF=gi:6446605 /UG=Hs.119120 E3 ubiquitin ligase SMURF1 AF199364 SMAD specific E3 ubiquitin protein ligase 1 SMURF1 57154 NM_001199847 /// NM_020429 /// NM_181349 /// XM_005250507 /// XM_006716061 /// XM_006716062 0000209 // protein polyubiquitination // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007398 // ectoderm development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030154 // cell differentiation // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0048185 // activin binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 215459_at AK001327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001327.1 /DEF=Homo sapiens cDNA FLJ10465 fis, clone NT2RP1001616. /FEA=mRNA /DB_XREF=gi:7022515 /UG=Hs.12956 Tax interaction protein 1 AK001327 cystinosin, lysosomal cystine transporter CTNS 1497 NM_001031681 /// NM_004937 /// XM_005256485 /// XM_006721463 /// XM_006721464 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015811 // L-cystine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from mutant phenotype /// 0015811 // L-cystine transport // non-traceable author statement /// 0046034 // ATP metabolic process // inferred from mutant phenotype /// 0048058 // compound eye corneal lens development // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // non-traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015184 // L-cystine transmembrane transporter activity // inferred from mutant phenotype /// 0015184 // L-cystine transmembrane transporter activity // non-traceable author statement 215460_x_at AL080149 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080149.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B094 (from clone DKFZp434B094); partial cds. /FEA=mRNA /GEN=DKFZp434B094 /PROD=hypothetical protein /DB_XREF=gi:5262602 /UG=Hs.127950 bromodomain-containing 1 AL080149 bromodomain containing 1 BRD1 23774 NM_014577 /// XM_005261470 /// XM_005261471 /// XM_005261472 /// XM_005261473 /// XM_006724210 /// XM_006724211 /// XM_006724212 /// XM_006724213 /// XM_006724214 /// XM_006724215 /// XM_006724216 /// XR_244359 /// XR_244360 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215461_at AI807507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI807507 /FEA=EST /DB_XREF=gi:5394073 /DB_XREF=est:wf48e10.x1 /CLONE=IMAGE:2358858 /UG=Hs.126496 Homo sapiens chromosome 19, cosmid R31343 AI807507 zinc and ring finger 4 ZNRF4 148066 NM_181710 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215462_at AI978990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI978990 /FEA=EST /DB_XREF=gi:5804020 /DB_XREF=est:wr68h11.x1 /CLONE=IMAGE:2492901 /UG=Hs.125258 Homo sapiens cDNA FLJ13795 fis, clone THYRO1000107 AI978990 polo-like kinase 3 PLK3 1263 NM_004073 /// XR_246234 0000075 // cell cycle checkpoint // inferred from sequence or structural similarity /// 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000084 // mitotic S phase // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000302 // response to reactive oxygen species // inferred from direct assay /// 0000910 // cytokinesis // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006970 // response to osmotic stress // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007113 // endomitotic cell cycle // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0051302 // regulation of cell division // inferred from direct assay /// 0090166 // Golgi disassembly // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 2000777 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215463_at BF062364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062364 /FEA=EST /DB_XREF=gi:10821274 /DB_XREF=est:7k77c12.x1 /CLONE=IMAGE:3481366 /UG=Hs.129832 olfactory receptor, family 7, subfamily E, member 24 pseudogene BF062364 olfactory receptor, family 7, subfamily E, member 24 OR7E24 26648 NM_001079935 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 215464_s_at AK001327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001327.1 /DEF=Homo sapiens cDNA FLJ10465 fis, clone NT2RP1001616. /FEA=mRNA /DB_XREF=gi:7022515 /UG=Hs.12956 Tax interaction protein 1 AK001327 purinergic receptor P2X, ligand-gated ion channel, 5 /// P2RX5-TAX1BP3 readthrough (NMD candidate) /// Tax1 (human T-cell leukemia virus type I) binding protein 3 P2RX5 /// P2RX5-TAX1BP3 /// TAX1BP3 5026 /// 30851 /// 100533970 NM_001204519 /// NM_001204520 /// NM_001204698 /// NM_002561 /// NM_014604 /// NM_175080 /// NM_175081 /// NR_037928 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032864 // activation of Cdc42 GTPase activity // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // not recorded /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction 215465_at AL080207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080207.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G232 (from clone DKFZp434G232). /FEA=mRNA /GEN=DKFZp434G232 /PROD=hypothetical protein /DB_XREF=gi:5262695 /UG=Hs.134585 DKFZP434G232 protein AL080207 ATP-binding cassette, sub-family A (ABC1), member 12 ABCA12 26154 NM_015657 /// NM_173076 /// NR_103740 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from direct assay /// 0006869 // lipid transport // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0031424 // keratinization // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0035627 // ceramide transport // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from mutant phenotype /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0097209 // epidermal lamellar body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0034040 // lipid-transporting ATPase activity // inferred by curator /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction 215466_at AF035314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035314.1 /DEF=Homo sapiens clone 23651 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661076 /UG=Hs.134526 Homo sapiens clone 23651 mRNA sequence AF035314 215467_x_at AK001442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001442.1 /DEF=Homo sapiens cDNA FLJ10580 fis, clone NT2RP2003533. /FEA=mRNA /DB_XREF=gi:7022701 /UG=Hs.140402 Homo sapiens cDNA FLJ10580 fis, clone NT2RP2003533 AK001442 uncharacterized LOC647070 LOC647070 647070 XR_041238 /// XR_041239 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215468_at AK001442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001442.1 /DEF=Homo sapiens cDNA FLJ10580 fis, clone NT2RP2003533. /FEA=mRNA /DB_XREF=gi:7022701 /UG=Hs.140402 Homo sapiens cDNA FLJ10580 fis, clone NT2RP2003533 AK001442 215469_at AF339807 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339807.1 /DEF=Homo sapiens clone IMAGE:26186, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507345 /UG=Hs.137567 Homo sapiens cDNA FLJ11627 fis, clone HEMBA1004225 AF339807 SLIT and NTRK-like family, member 5 SLITRK5 26050 NM_015567 /// XM_005254038 /// XM_005254039 0007268 // synaptic transmission // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215470_at U21915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U21915.1 /DEF=Human chromosome 5q13.1 clone 5G8 mRNA. /FEA=mRNA /DB_XREF=gi:736412 /UG=Hs.14658 Human chromosome 5q13.1 clone 5G8 mRNA U21915 general transcription factor IIH, polypeptide 2B (pseudogene) GTF2H2B 653238 NM_001098729 /// NR_033417 215471_s_at AJ242502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ242502.1 /DEF=Homo sapiens mRNA for E-MAP-115105 (MAP gene). /FEA=CDS /GEN=MAP /PROD=epithelial microtubule-associated protein /DB_XREF=gi:7581984 /UG=Hs.146388 microtubule-associated protein 7 AJ242502 microtubule-associated protein 7 MAP7 9053 NM_001198608 /// NM_001198609 /// NM_001198611 /// NM_001198614 /// NM_001198615 /// NM_001198616 /// NM_001198617 /// NM_001198618 /// NM_001198619 /// NM_003980 /// XM_005267209 /// XM_006715598 /// XM_006715599 /// XM_006715600 /// XM_006715601 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from sequence or structural similarity /// 0006997 // nucleus organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215472_at AI017119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI017119 /FEA=EST /DB_XREF=gi:3231455 /DB_XREF=est:ov34a05.x1 /CLONE=IMAGE:1639184 /UG=Hs.144339 Human DNA sequence from clone RP1-257A15 on chromosome 6. Contains ESTs, STSs, GSSs and a CpG island. Contains a putative novel gene and a novel gene AI017119 PARK2 co-regulated PACRG 135138 NM_001080378 /// NM_001080379 /// NM_152410 /// XM_005266824 /// XM_005266825 /// XM_005266826 /// XM_006715343 /// XM_006715344 /// XM_006715345 0007286 // spermatid development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0097225 // sperm midpiece // inferred from electronic annotation 215473_at AF052140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052140.1 /DEF=Homo sapiens clone 23758 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360449 /UG=Hs.141055 Homo sapiens clone 23758 mRNA sequence AF052140 215474_at AK022094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022094.1 /DEF=Homo sapiens cDNA FLJ12032 fis, clone HEMBB1001880. /FEA=mRNA /DB_XREF=gi:10433415 /UG=Hs.151194 Homo sapiens cDNA FLJ12032 fis, clone HEMBB1001880 AK022094 215475_at AK022094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022094.1 /DEF=Homo sapiens cDNA FLJ12032 fis, clone HEMBB1001880. /FEA=mRNA /DB_XREF=gi:10433415 /UG=Hs.151194 Homo sapiens cDNA FLJ12032 fis, clone HEMBB1001880 AK022094 215476_at AF052103 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052103.1 /DEF=Homo sapiens clone 23726 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360410 /UG=Hs.159157 Homo sapiens clone 23726 mRNA sequence AF052103 215477_at H49077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H49077 /FEA=EST /DB_XREF=gi:988918 /DB_XREF=est:yq18c05.s1 /CLONE=IMAGE:274160 /UG=Hs.159179 Homo sapiens mRNA sequence, IMAGE clone 446411 H49077 215478_at AF007156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007156.1 /DEF=Homo sapiens clone 23617 unknown mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:2852637 /UG=Hs.153610 KIAA0751 gene product AF007156 regulating synaptic membrane exocytosis 2 RIMS2 9699 NM_001100117 /// NM_001282881 /// NM_001282882 /// NM_014677 /// XM_005251106 /// XM_005251107 /// XM_005251108 /// XM_006716690 /// XM_006716691 /// XM_006716692 /// XM_006716693 /// XM_006716694 /// XM_006716695 /// XM_006716696 /// XM_006716697 /// XM_006716698 /// XM_006716699 0006886 // intracellular protein transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215479_at AK000787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000787.1 /DEF=Homo sapiens cDNA FLJ20780 fis, clone COL04256. /FEA=mRNA /DB_XREF=gi:7021089 /UG=Hs.157392 Homo sapiens cDNA FLJ20780 fis, clone COL04256 AK000787 215480_at AB007978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007978.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0509. /FEA=mRNA /DB_XREF=gi:3413953 /UG=Hs.158278 KIAA0509 protein AB007978 uncharacterized LOC57242 KIAA0509 57242 215481_s_at AW468717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW468717 /FEA=EST /DB_XREF=gi:7038823 /DB_XREF=est:hd26h06.x1 /CLONE=IMAGE:2910683 /UG=Hs.158084 peroxisome receptor 1 AW468717 peroxisomal biogenesis factor 5 PEX5 5830 NM_000319 /// NM_001131023 /// NM_001131024 /// NM_001131025 /// NM_001131026 /// XM_005253451 /// XM_005253452 /// XM_005253453 /// XM_005253455 /// XM_006719129 /// XM_006719130 /// XM_006719131 /// XM_006719132 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from genetic interaction /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // non-traceable author statement /// 0016560 // protein import into peroxisome matrix, docking // inferred from direct assay /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0048468 // cell development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from mutant phenotype /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 215482_s_at AJ011307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ011307 /DEF=Homo sapiens eIF2B delta subunit gene, exons 1-11 /FEA=CDS_2 /DB_XREF=gi:6012056 /UG=Hs.169474 DKFZP586J0119 protein AJ011307 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa EIF2B4 8890 NM_001034116 /// NM_015636 /// NM_172195 /// XM_005264632 /// XM_006712132 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // non-traceable author statement /// 0006446 // regulation of translational initiation // not recorded /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0032057 // negative regulation of translational initiation in response to stress // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // not recorded /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 215483_at AK000270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000270.1 /DEF=Homo sapiens cDNA FLJ20263 fis, clone COLF7804, highly similar to AJ131693 Homo sapiens mRNA for AKAP450 protein. /FEA=mRNA /DB_XREF=gi:7020239 /UG=Hs.164036 Homo sapiens AKAP350C mRNA sequence, alternatively spliced AK000270 A kinase (PRKA) anchor protein 9 AKAP9 10142 NM_005751 /// NM_147166 /// NM_147171 /// NM_147185 /// XM_005250102 /// XM_005250103 /// XM_006715827 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 215484_at AF070538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070538.1 /DEF=Homo sapiens clone 24420 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387895 /UG=Hs.159408 Homo sapiens clone 24420 mRNA sequence AF070538 215485_s_at AA284705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284705 /FEA=EST /DB_XREF=gi:1927264 /DB_XREF=est:zt20g08.r1 /CLONE=IMAGE:713726 /UG=Hs.168383 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor AA284705 intercellular adhesion molecule 1 ICAM1 3383 NM_000201 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001910 // regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from electronic annotation /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007569 // cell aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010477 // response to sulfur dioxide // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 215486_at AW072461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW072461 /FEA=EST /DB_XREF=gi:6027459 /DB_XREF=est:xa06c09.x1 /CLONE=IMAGE:2567536 /UG=Hs.169284 Homo sapiens phosphoribosylpyrophosphate synthetase subunit III mRNA, 3 end AW072461 phosphoribosyl pyrophosphate synthetase 1-like 1 PRPS1L1 221823 NM_175886 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044249 // cellular biosynthetic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from sequence or structural similarity /// 0004749 // ribose phosphate diphosphokinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215487_x_at AL096727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096727.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B104 (from clone DKFZp434B104). /FEA=mRNA /DB_XREF=gi:5419860 /UG=Hs.168249 Homo sapiens mRNA; cDNA DKFZp434B104 (from clone DKFZp434B104) AL096727 family with sequence similarity 182, member B /// family with sequence similarity 27, member B /// family with sequence similarity 27, member C FAM182B /// FAM27B /// FAM27C 728882 /// 100132948 /// 100133121 NM_001024942 /// NR_024060 /// NR_026714 /// NR_027061 /// NR_027421 /// NR_027422 215488_at AF052095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052095.1 /DEF=Homo sapiens clone 23911 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360401 /UG=Hs.167344 Homo sapiens clone 23911 mRNA sequence AF052095 215489_x_at AI871287 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI871287 /FEA=EST /DB_XREF=gi:5545255 /DB_XREF=est:wl80h02.x1 /CLONE=IMAGE:2431251 /UG=Hs.166146 Homer, neuronal immediate early gene, 3 AI871287 homer homolog 3 (Drosophila) HOMER3 9454 NM_001145721 /// NM_001145722 /// NM_001145724 /// NM_004838 /// NR_027297 /// XM_006722943 /// XM_006722944 0006605 // protein targeting // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 215490_at AK023911 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023911.1 /DEF=Homo sapiens cDNA FLJ13849 fis, clone THYRO1000865. /FEA=mRNA /DB_XREF=gi:10435992 /UG=Hs.181810 Homo sapiens cDNA FLJ13849 fis, clone THYRO1000865 AK023911 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) IBA57 200205 NM_001010867 /// XM_006711753 0006546 // glycine catabolic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215491_at AI273812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI273812 /FEA=EST /DB_XREF=gi:3896080 /DB_XREF=est:qu08f07.x1 /CLONE=IMAGE:1964197 /UG=Hs.169252 Human L-myc protein gene, complete cds AI273812 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog MYCL 4610 NM_001033081 /// NM_001033082 /// NM_005376 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 215492_x_at AL035587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035587 /DEF=Human DNA sequence from clone RP3-475N16 on chromosome 6p12.3-21.2. Contains the genes for CTG4A, pre-T cell receptor alpha, a novel protein similar to RPL7A (60S ribosomal protein L7A) and the 3 end of gene KIAA0240. Contains ESTs, STSs, GSSs an... /FEA=mRNA_2 /DB_XREF=gi:6002306 /UG=Hs.169002 Human pre TCR alpha mRNA, partial cds AL035587 pre T-cell antigen receptor alpha PTCRA 171558 NM_001243168 /// NM_001243169 /// NM_001243170 /// NM_138296 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 215493_x_at AL121936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121936 /DEF=Human DNA sequence from clone CTA-14H9 on chromosome 6 Contains the 3 end of the BTN2A1 gene encoding butyrophilin 2A, the BTN1A1 gene encoding butyrophilin 1A, the HMG17L3 gene encoding two putative isoforms of the high-mobility group (nonhisto... /FEA=mRNA_2 /DB_XREF=gi:10862830 /UG=Hs.169963 butyrophilin, subfamily 2, member A1 AL121936 butyrophilin, subfamily 2, member A1 BTN2A1 11120 NM_001197233 /// NM_001197234 /// NM_007049 /// NM_078476 0006629 // lipid metabolic process // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 215494_at AF174394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF174394.1 /DEF=Homo sapiens apoptotic-related protein PCAR mRNA, partial cds. /FEA=mRNA /PROD=apoptotic-related protein PCAR /DB_XREF=gi:5802906 /UG=Hs.177461 Homo sapiens apoptotic-related protein PCAR mRNA, partial cds AF174394 215495_s_at AL117523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117523.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0350 (from clone DKFZp434H0350); partial cds. /FEA=mRNA /GEN=DKFZp434H0350 /PROD=hypothetical protein /DB_XREF=gi:5912039 /UG=Hs.173571 KIAA1053 protein AL117523 sterile alpha motif domain containing 4A SAMD4A 23034 NM_001161576 /// NM_001161577 /// NM_015589 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030371 // translation repressor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 215496_at AL117523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117523.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0350 (from clone DKFZp434H0350); partial cds. /FEA=mRNA /GEN=DKFZp434H0350 /PROD=hypothetical protein /DB_XREF=gi:5912039 /UG=Hs.173571 KIAA1053 protein AL117523 sterile alpha motif domain containing 4A SAMD4A 23034 NM_001161576 /// NM_001161577 /// NM_015589 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0030371 // translation repressor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 215497_s_at AK023778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023778.1 /DEF=Homo sapiens cDNA FLJ13716 fis, clone PLACE2000411, highly similar to Homo sapiens epsin 2b mRNA. /FEA=mRNA /DB_XREF=gi:10435813 /UG=Hs.172825 KIAA1037 protein AK023778 WD and tetratricopeptide repeats 1 WDTC1 23038 NM_001276252 /// NM_015023 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0055082 // cellular chemical homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation 215498_s_at AA780381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA780381 /FEA=EST /DB_XREF=gi:2839712 /DB_XREF=est:aa67a09.s1 /CLONE=IMAGE:825976 /UG=Hs.180533 mitogen-activated protein kinase kinase 3 AA780381 dual specificity mitogen-activated protein kinase kinase 3-like /// mitogen-activated protein kinase kinase 3 LOC100996792 /// MAP2K3 5606 /// 100996792 NM_002756 /// NM_145109 /// NM_145110 /// XM_003846747 /// XM_005256721 /// XM_005256722 /// XM_005256723 /// XR_429863 /// XR_429864 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 215499_at AA780381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA780381 /FEA=EST /DB_XREF=gi:2839712 /DB_XREF=est:aa67a09.s1 /CLONE=IMAGE:825976 /UG=Hs.180533 mitogen-activated protein kinase kinase 3 AA780381 dual specificity mitogen-activated protein kinase kinase 3-like /// mitogen-activated protein kinase kinase 3 LOC100996792 /// MAP2K3 5606 /// 100996792 NM_002756 /// NM_145109 /// NM_145110 /// XM_003846747 /// XM_005256721 /// XM_005256722 /// XM_005256723 /// XR_429863 /// XR_429864 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 215500_at U95737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U95737 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-388D4 /FEA=mRNA /DB_XREF=gi:3417290 /UG=Hs.177961 Human Chromosome 16 BAC clone CIT987SK-A-388D4 U95737 uncharacterized LOC101929304 /// sorting nexin 29 LOC101929304 /// SNX29 92017 /// 101929304 NM_001009607 /// NM_001080530 /// NM_032167 /// XM_005255682 /// XM_005255683 /// XM_005255755 /// XM_006720977 /// XM_006720978 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005871 // kinesin complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003777 // microtubule motor activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 215501_s_at AK022513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022513.1 /DEF=Homo sapiens cDNA FLJ12451 fis, clone NT2RM1000377, highly similar to Homo sapiens dual specificity phosphatase MKP5 (MKP5) mRNA. /FEA=mRNA /DB_XREF=gi:10433943 /UG=Hs.177534 dual specificity phosphatase 10 AK022513 dual specificity phosphatase 10 DUSP10 11221 NM_007207 /// NM_144728 /// NM_144729 /// NR_111939 /// NR_111940 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0002819 // regulation of adaptive immune response // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // not recorded /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // not recorded /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from direct assay 215502_at R37655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R37655 /FEA=EST /DB_XREF=gi:795111 /DB_XREF=est:yf61d03.s1 /CLONE=IMAGE:26881 /UG=Hs.194761 H.sapiens IMAGE cDNA clone 26881 R37655 LA16c-381G6.1 215503_at AW118166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW118166 /FEA=EST /DB_XREF=gi:6086750 /DB_XREF=est:xd80b11.x1 /CLONE=IMAGE:2603901 /UG=Hs.184930 serine protease inhibitor, Kunitz type, 3 AW118166 serine peptidase inhibitor, Kunitz type, 3 SPINT3 10816 NM_006652 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 215504_x_at AF131777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131777.1 /DEF=Homo sapiens clone 25061 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406602 /UG=Hs.183475 Homo sapiens clone 25061 mRNA sequence AF131777 ANKRD10 intronic transcript 1 (non-protein coding) ANKRD10-IT1 100505494 XR_109155 /// XR_111397 /// XR_172017 215505_s_at AF243424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF243424.1 /DEF=Homo sapiens SG2NA beta isoform mRNA, partial cds. /FEA=mRNA /PROD=SG2NA beta isoform /DB_XREF=gi:8895998 /UG=Hs.183105 nuclear autoantigen AF243424 striatin, calmodulin binding protein 3 STRN3 29966 NM_001083893 /// NM_014574 /// XM_005267569 /// XM_005267570 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0032355 // response to estradiol // inferred from sequence or structural similarity /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 215506_s_at AK021882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021882.1 /DEF=Homo sapiens cDNA FLJ11820 fis, clone HEMBA1006445, highly similar to Homo sapiens putative tumor supressor NOEY2 mRNA. /FEA=mRNA /DB_XREF=gi:10433168 /UG=Hs.194695 ras homolog gene family, member I AK021882 DIRAS family, GTP-binding RAS-like 3 DIRAS3 9077 NM_004675 /// XM_006711027 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 215507_x_at AL049985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049985.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E122 (from clone DKFZp564E122). /FEA=mRNA /DB_XREF=gi:4884236 /UG=Hs.19180 Homo sapiens mRNA; cDNA DKFZp564E122 (from clone DKFZp564E122) AL049985 215508_at AL137654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137654.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C0814 (from clone DKFZp434C0814). /FEA=mRNA /DB_XREF=gi:6807722 /UG=Hs.194110 hypothetical protein PRO2730 AL137654 BUB1 mitotic checkpoint serine/threonine kinase BUB1 699 NM_001278616 /// NM_001278617 /// NM_004336 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007063 // regulation of sister chromatid cohesion // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype /// 0071173 // spindle assembly checkpoint // inferred from direct assay /// 0071173 // spindle assembly checkpoint // inferred from mutant phenotype /// 0071174 // mitotic spindle checkpoint // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215509_s_at AL137654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137654.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C0814 (from clone DKFZp434C0814). /FEA=mRNA /DB_XREF=gi:6807722 /UG=Hs.194110 hypothetical protein PRO2730 AL137654 BUB1 mitotic checkpoint serine/threonine kinase BUB1 699 NM_001278616 /// NM_001278617 /// NM_004336 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007063 // regulation of sister chromatid cohesion // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype /// 0071173 // spindle assembly checkpoint // inferred from direct assay /// 0071173 // spindle assembly checkpoint // inferred from mutant phenotype /// 0071174 // mitotic spindle checkpoint // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215510_at AV693985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV693985 /FEA=EST /DB_XREF=gi:10295848 /DB_XREF=est:AV693985 /CLONE=GKCCYE06 /UG=Hs.194061 ets variant gene 2 AV693985 ets variant 2 ETV2 2116 NM_014209 /// XM_005258652 /// XM_005258653 /// XM_005258654 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060803 // BMP signaling pathway involved in mesodermal cell fate specification // inferred from electronic annotation /// 2000382 // positive regulation of mesoderm development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 215511_at U19345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U19345.1 /DEF=Homo sapiens AR1 (TCF20) mRNA, partial cds. /FEA=mRNA /GEN=TCF20 /PROD=AR1 /DB_XREF=gi:2924754 /UG=Hs.201668 transcription factor 20 (AR1) U19345 transcription factor 20 (AR1) TCF20 6942 NM_005650 /// NM_181492 /// XM_005261722 /// XM_005261723 /// XM_005261724 /// XM_005276955 /// XM_005276956 /// XM_005276957 /// XM_006724313 /// XM_006724314 /// XM_006725781 /// XM_006725782 /// XM_006725783 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215512_at AK000970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000970.1 /DEF=Homo sapiens cDNA FLJ10108 fis, clone HEMBA1002609, highly similar to Homo sapiens mRNA for KIAA0597 protein. /FEA=mRNA /DB_XREF=gi:7021963 /UG=Hs.20141 similar to S. cerevisiae SSM4 AK000970 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase MARCH6 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215513_at AF241534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF241534.1 /DEF=Homo sapiens hydatidiform mole associated and imprinted (HYMAI) mRNA, complete sequence. /FEA=mRNA /DB_XREF=gi:9502099 /UG=Hs.196015 hydatidiform mole associated and imprinted AF241534 hydatidiform mole associated and imprinted (non-protein coding) HYMAI 57061 NR_002768 215514_at AL080072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080072.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M0616 (from clone DKFZp564M0616). /FEA=mRNA /DB_XREF=gi:5262482 /UG=Hs.21195 Homo sapiens mRNA; cDNA DKFZp564M0616 (from clone DKFZp564M0616) AL080072 RP4-621B10.8 215515_at AL049268 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049268.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G103 (from clone DKFZp564G103). /FEA=mRNA /DB_XREF=gi:4500017 /UG=Hs.202684 Homo sapiens mRNA; cDNA DKFZp564G103 (from clone DKFZp564G103) AL049268 215516_at AC005048 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005048 /DEF=Homo sapiens BAC clone CTB-15P3 from 7q22-q31.2 /FEA=CDS /DB_XREF=gi:4508116 /UG=Hs.202688 laminin, beta 4 AC005048 laminin, beta 4 LAMB4 22798 NM_007356 /// XM_005250232 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 215517_at AL049925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049925.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G0982 (from clone DKFZp564G0982); partial cds. /FEA=mRNA /GEN=DKFZp564G0982 /PROD=hypothetical protein /DB_XREF=gi:4884172 /UG=Hs.225984 DKFZP547G0910 protein AL049925 pygopus family PHD finger 1 PYGO1 26108 NM_015617 /// XM_005254300 0001822 // kidney development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215518_at AB023223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB023223.1 /DEF=Homo sapiens mRNA for KIAA1006 protein, partial cds. /FEA=mRNA /GEN=KIAA1006 /PROD=KIAA1006 protein /DB_XREF=gi:4589655 /UG=Hs.225969 tomosyn AB023223 syntaxin binding protein 5-like STXBP5L 9515 NM_014980 /// XM_005247907 /// XM_006713825 /// XM_006713826 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 215519_x_at AI081779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI081779 /FEA=EST /DB_XREF=gi:3418571 /DB_XREF=est:ox73g01.x1 /CLONE=IMAGE:1662000 /UG=Hs.22129 hypothetical protein AI081779 small G protein signaling modulator 3 SGSM3 27352 NM_015705 /// XM_005261572 /// XM_005261573 /// XM_005261574 /// XM_005261575 /// XM_005261577 /// XM_005261579 /// XR_244369 /// XR_244370 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032483 // regulation of Rab protein signal transduction // inferred from expression pattern /// 0032486 // Rap protein signal transduction // inferred from expression pattern /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from direct assay 215520_at AL049925 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049925.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G0982 (from clone DKFZp564G0982); partial cds. /FEA=mRNA /GEN=DKFZp564G0982 /PROD=hypothetical protein /DB_XREF=gi:4884172 /UG=Hs.225984 DKFZP547G0910 protein AL049925 pygopus family PHD finger 1 PYGO1 26108 NM_015617 /// XM_005254300 0001822 // kidney development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215521_at AK023029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023029.1 /DEF=Homo sapiens cDNA FLJ12967 fis, clone NT2RP2005806. /FEA=mRNA /DB_XREF=gi:10434754 /UG=Hs.231977 hypothetical protein FLJ12729 AK023029 polyhomeotic homolog 3 (Drosophila) PHC3 80012 NM_024947 /// XM_005247789 /// XM_005247790 /// XM_005247791 /// XM_005247793 /// XM_006713753 /// XM_006713754 /// XM_006713755 /// XM_006713756 /// XM_006713757 /// XR_241509 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215522_at AB028982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028982.1 /DEF=Homo sapiens mRNA for KIAA1059 protein, partial cds. /FEA=mRNA /GEN=KIAA1059 /PROD=KIAA1059 protein /DB_XREF=gi:5689454 /UG=Hs.225976 KIAA1059 protein AB028982 sortilin-related VPS10 domain containing receptor 3 SORCS3 22986 NM_014978 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008188 // neuropeptide receptor activity // non-traceable author statement 215523_at AL031118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031118 /DEF=Human DNA sequence from clone 153G14 on chromosome 6p21.3-22.2. Contains the 3 end of the ZNF184 gene for Kruppel-like zinc finger protein 184, a gene for a PUTATIVE novel protein similar to worm F55A11.1 and T04F3.4, part of a gene for a novel C... /FEA=CDS_1 /DB_XREF=gi:10191005 /UG=Hs.226013 Human DNA sequence from clone 153G14 on chromosome 6p21.3-22.2. Contains the 3 end of the ZNF184 gene for Kruppel-like zinc finger protein 184, a gene for a PUTATIVE novel protein similar to worm F55A11.1 and T04F3.4, part of a gene for a novel C2H2 type AL031118 zinc finger protein 391 ZNF391 346157 NM_001013719 /// NM_001076781 /// XM_005249082 /// XM_006715086 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215524_x_at AW966434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW966434 /FEA=EST /DB_XREF=gi:8156270 /DB_XREF=est:EST378508 /UG=Hs.250654 Homo sapiens T-cell receptor alpha delta locus from bases 752679 to 1000555 (section 4 of 5) of the Complete Nucleotide Sequence AW966434 uncharacterized protein MGC40069 /// T cell receptor alpha constant /// T cell receptor alpha joining 17 /// T cell receptor alpha variable 20 /// T cell receptor delta variable 2 /// YME1-like 1 ATPase MGC40069 /// TRAC /// TRAJ17 /// TRAV20 /// TRDV2 /// YME1L1 10730 /// 28517 /// 28663 /// 28738 /// 28755 /// 348035 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 215525_at AL050185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050185.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586A0423 (from clone DKFZp586A0423). /FEA=mRNA /DB_XREF=gi:4884400 /UG=Hs.225988 Homo sapiens mRNA; cDNA DKFZp586A0423 (from clone DKFZp586A0423) AL050185 215526_at AL050145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050145.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C2020 (from clone DKFZp586C2020). /FEA=mRNA /DB_XREF=gi:4884356 /UG=Hs.225986 Homo sapiens mRNA; cDNA DKFZp586C2020 (from clone DKFZp586C2020) AL050145 215527_at AL049544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049544 /DEF=Human DNA sequence from clone 240B8 on chromosome 6p11.2-q12. Contains the 3 part of a gene for a novel protein similar to T-STAR, Etoile, Sam68, SLM1 and p62 Tyrosine Phosphoprotein. Contains ESTs, STSs, GSSs and genomic marker D6S1695 /FEA=mRNA /DB_XREF=gi:4757047 /UG=Hs.226014 Human DNA sequence from clone 240B8 on chromosome 6p11.2-q12. Contains the 3 part of a gene for a novel protein similar to T-STAR, Etoile, Sam68, SLM1 and p62 Tyrosine Phosphoprotein. Contains ESTs, STSs, GSSs and genomic marker D6S1695 AL049544 KH domain containing, RNA binding, signal transduction associated 2 KHDRBS2 202559 NM_152688 /// XM_006715354 /// XM_006715355 /// XR_427965 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0008266 // poly(U) RNA binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215528_at AL049390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049390.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586O1318 (from clone DKFZp586O1318). /FEA=mRNA /DB_XREF=gi:4500184 /UG=Hs.22689 Homo sapiens mRNA; cDNA DKFZp586O1318 (from clone DKFZp586O1318) AL049390 215529_x_at AI590053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI590053 /FEA=EST /DB_XREF=gi:4599101 /DB_XREF=est:tr75d05.x1 /CLONE=IMAGE:2224137 /UG=Hs.235160 Homo sapiens mRNA; cDNA DKFZp434G0572 (from clone DKFZp434G0572); partial cds AI590053 DIP2 disco-interacting protein 2 homolog A (Drosophila) DIP2A 23181 NM_001146114 /// NM_001146115 /// NM_001146116 /// NM_015151 /// NM_206889 /// NM_206890 /// NM_206891 /// XM_006723980 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation 215530_at BG484069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG484069 /FEA=EST /DB_XREF=gi:13416348 /DB_XREF=est:602504673F1 /CLONE=IMAGE:4617907 /UG=Hs.240138 Homo sapiens FANCA gene, exon 10a BG484069 Fanconi anemia, complementation group A FANCA 2175 NM_000135 /// NM_001018112 /// NM_001286167 /// XM_005256294 /// XM_006721167 /// XM_006721168 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215531_s_at BF966183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF966183 /FEA=EST /DB_XREF=gi:12333398 /DB_XREF=est:602286485F1 /CLONE=IMAGE:4375389 /UG=Hs.24969 gamma-aminobutyric acid (GABA) A receptor, alpha 5 BF966183 gamma-aminobutyric acid (GABA) A receptor, alpha 5 GABRA5 2558 NM_000810 /// NM_001165037 /// XM_005268258 /// XM_006720459 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 215532_x_at AB040906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040906.1 /DEF=Homo sapiens mRNA for KIAA1473 protein, partial cds. /FEA=mRNA /GEN=KIAA1473 /PROD=KIAA1473 protein /DB_XREF=gi:7959206 /UG=Hs.232108 KIAA1473 protein AB040906 zinc finger protein 492 ZNF492 57615 NM_020855 /// XM_006722805 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215533_s_at AF091093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF091093.1 /DEF=Homo sapiens clone 686 unknown mRNA, complete sequence. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3860023 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) AF091093 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 215534_at AL117546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117546.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C1923 (from clone DKFZp586C1923). /FEA=mRNA /DB_XREF=gi:5912079 /UG=Hs.241429 Homo sapiens mRNA; cDNA DKFZp586C1923 (from clone DKFZp586C1923) AL117546 215535_s_at AF007145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007145.1 /DEF=Homo sapiens clone 23552 unknown mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:2852622 /UG=Hs.240534 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) AF007145 1-acylglycerol-3-phosphate O-acyltransferase 1 AGPAT1 10554 NM_006411 /// NM_032741 /// XM_005248805 /// XM_005248806 /// XM_005272761 /// XM_005272762 /// XM_005274829 /// XM_005274830 /// XM_005275073 /// XM_005275074 /// XM_005275203 /// XM_005275204 /// XM_005275337 /// XM_005275338 /// XM_005275504 /// XM_005275505 0001819 // positive regulation of cytokine production // inferred from mutant phenotype /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred by curator /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // inferred from genetic interaction /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from genetic interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215536_at X87344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X87344 /DEF=H.sapiens DMA, DMB, HLA-Z1, IPP2, LMP2, TAP1, LMP7, TAP2, DOB, DQB2 and RING8, 9, 13 and 14 genes /FEA=mRNA_2 /DB_XREF=gi:1054740 /UG=Hs.247964 H.sapiens DMA, DMB, HLA-Z1, IPP2, LMP2, TAP1, LMP7, TAP2, DOB, DQB2 and RING8, 9, 13 and 14 genes X87344 major histocompatibility complex, class II, DQ beta 2 HLA-DQB2 3120 NM_001198858 /// NM_182549 /// NR_003937 /// XM_005249051 /// XM_005272807 /// XM_005274855 /// XM_005275546 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // non-traceable author statement /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement 215537_x_at AJ012008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ012008 /DEF=Homo sapiens genes encoding RNCC protein, DDAH protein, Ly6-C protein, Ly6-D protein and immunoglobulin receptor /FEA=mRNA_4 /DB_XREF=gi:5304874 /UG=Hs.247362 dimethylarginine dimethylaminohydrolase 2 AJ012008 dimethylarginine dimethylaminohydrolase 2 DDAH2 23564 NM_013974 /// XM_005248974 /// XM_005272783 /// XM_005274929 /// XM_005275086 /// XM_005275225 /// XM_005275361 /// XM_005275522 0000052 // citrulline metabolic process // inferred from direct assay /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016403 // dimethylargininase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation 215538_at BF057493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057493 /FEA=EST /DB_XREF=gi:10811389 /DB_XREF=est:7k44h02.x1 /CLONE=IMAGE:3478491 /UG=Hs.25220 like-glycosyltransferase BF057493 215539_at AK021967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021967.1 /DEF=Homo sapiens cDNA FLJ11905 fis, clone HEMBB1000050. /FEA=mRNA /DB_XREF=gi:10433276 /UG=Hs.273759 Homo sapiens cDNA FLJ11905 fis, clone HEMBB1000050 AK021967 215540_at AW950865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW950865 /FEA=EST /DB_XREF=gi:8140527 /DB_XREF=est:EST362935 /UG=Hs.251470 Homo sapiens T-cell receptor alpha delta locus from bases 501613 to 752736 (section 3 of 5) of the Complete Nucleotide Sequence AW950865 SubName: Full=TRA@ protein; /// YME1-like 1 ATPase TRA@ /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 215541_s_at AK023345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023345.1 /DEF=Homo sapiens cDNA FLJ13283 fis, clone OVARC1001113, highly similar to Homo sapiens diaphanous 1 (HDIA1) mRNA. /FEA=mRNA /DB_XREF=gi:10435238 /UG=Hs.26584 diaphanous (Drosophila, homolog) 1 AK023345 diaphanous-related formin 1 DIAPH1 1729 NM_001079812 /// NM_005219 /// XM_005268384 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071420 // cellular response to histamine // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215542_at AK023121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023121.1 /DEF=Homo sapiens cDNA FLJ13059 fis, clone NT2RP3001589. /FEA=mRNA /DB_XREF=gi:10434898 /UG=Hs.255874 hypothetical protein FLJ13059 AK023121 215543_s_at AB011181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011181.2 /DEF=Homo sapiens mRNA for KIAA0609 protein, partial cds. /FEA=mRNA /GEN=KIAA0609 /PROD=KIAA0609 protein /DB_XREF=gi:6683718 /UG=Hs.25220 like-glycosyltransferase AB011181 like-glycosyltransferase LARGE 9215 NM_004737 /// NM_133642 /// XM_005261831 /// XM_005261832 /// XM_006724375 0006044 // N-acetylglucosamine metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // traceable author statement 215544_s_at AL121891 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121891 /DEF=Human DNA sequence from clone RP5-1187M17 on chromosome 20 Contains the KIAA0860 gene encoding a putative zinc-finger protein (isoform 1) and a novel protein (isoform 2), the KIAA0552 gene, a novel gene, the 5end of the AVP gene encoding arginine... /FEA=mRNA_3 /DB_XREF=gi:9367201 /UG=Hs.26009 KIAA0860 protein AL121891 U-box domain containing 5 UBOX5 22888 NM_001267584 /// NM_014948 /// NM_199415 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215545_at AK024185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024185.1 /DEF=Homo sapiens cDNA FLJ14123 fis, clone MAMMA1002155. /FEA=mRNA /DB_XREF=gi:10436502 /UG=Hs.269314 Homo sapiens cDNA FLJ14123 fis, clone MAMMA1002155 AK024185 215546_at AK001065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001065.1 /DEF=Homo sapiens cDNA FLJ10203 fis, clone HEMBA1004930, moderately similar to 26S PROTEASOME SUBUNIT S5B. /FEA=mRNA /DB_XREF=gi:7022101 /UG=Hs.273721 Homo sapiens cDNA FLJ10203 fis, clone HEMBA1004930, moderately similar to 26S PROTEASOME SUBUNIT S5B AK001065 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 PSMD5 5711 NM_001270427 /// NM_005047 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // traceable author statement 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 215547_at AF201291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF201291.1 /DEF=Homo sapiens TSC22-related inducible leucine zipper 4b (TILZ4b) mRNA, partial cds. /FEA=mRNA /GEN=TILZ4b /PROD=TSC22-related inducible leucine zipper 4b /DB_XREF=gi:11907583 /UG=Hs.52526 KIAA0669 gene product AF201291 TSC22 domain family, member 2 TSC22D2 9819 NM_014779 /// XM_005247920 /// XR_427388 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 215548_s_at AB020724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020724.1 /DEF=Homo sapiens mRNA for KIAA0917 protein, partial cds. /FEA=mRNA /GEN=KIAA0917 /PROD=KIAA0917 protein /DB_XREF=gi:4240322 /UG=Hs.27023 vesicle transport-related protein AB020724 sec1 family domain containing 1 SCFD1 23256 NM_001257376 /// NM_001283031 /// NM_001283032 /// NM_001283033 /// NM_016106 /// NM_182835 /// XM_005267469 /// XR_429299 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from sequence or structural similarity /// 0006892 // post-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from sequence or structural similarity /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from sequence or structural similarity /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from sequence or structural similarity /// 0047485 // protein N-terminus binding // inferred from electronic annotation 215549_x_at AC005587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005587 /DEF=Homo sapiens PAC clone RP5-988G15 from 7q33-q35 /FEA=CDS_2 /DB_XREF=gi:4156166 /UG=Hs.272525 Homo sapiens PAC clone RP5-988G15 from 7q33-q35 AC005587 CTAGE family, member 4 /// CTAGE family, member 8 /// CTAGE family, member 9 CTAGE4 /// CTAGE8 /// CTAGE9 643854 /// 100128553 /// 100142659 NM_001145659 /// NM_001278507 /// NM_198495 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation 215550_at AL137457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137457.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566G231 (from clone DKFZp566G231). /FEA=mRNA /DB_XREF=gi:6808035 /UG=Hs.272324 Homo sapiens mRNA; cDNA DKFZp566G231 (from clone DKFZp566G231) AL137457 SLIT-ROBO Rho GTPase activating protein 3 SRGAP3 9901 NM_001033116 /// NM_001033117 /// NM_014850 /// XM_005265622 /// XM_006713433 /// XR_427300 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215551_at AI073549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073549 /FEA=EST /DB_XREF=gi:3400193 /DB_XREF=est:ov45e08.x1 /CLONE=IMAGE:1640294 /UG=Hs.272288 Human DNA sequence from clone RP1-63I5 on chromosome 6q25.1-26. Contains the 3 part of a novel gene and an exon of the ESR1 gene for estrogen receptor 1 (NR3A1, estradiol receptor), ESTs, STSs and GSSs AI073549 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215552_s_at AI073549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073549 /FEA=EST /DB_XREF=gi:3400193 /DB_XREF=est:ov45e08.x1 /CLONE=IMAGE:1640294 /UG=Hs.272288 Human DNA sequence from clone RP1-63I5 on chromosome 6q25.1-26. Contains the 3 part of a novel gene and an exon of the ESR1 gene for estrogen receptor 1 (NR3A1, estradiol receptor), ESTs, STSs and GSSs AI073549 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215553_x_at AK024315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024315.1 /DEF=Homo sapiens cDNA FLJ14253 fis, clone OVARC1001376. /FEA=mRNA /DB_XREF=gi:10436666 /UG=Hs.300694 Homo sapiens cDNA FLJ14253 fis, clone OVARC1001376 AK024315 215554_at AV699786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV699786 /FEA=EST /DB_XREF=gi:10301757 /DB_XREF=est:AV699786 /CLONE=GKCGSA12 /UG=Hs.272529 glycosylphosphatidylinositol specific phospholipase D1 AV699786 glycosylphosphatidylinositol specific phospholipase D1 GPLD1 2822 NM_001503 /// NM_177483 /// XM_005249018 0001503 // ossification // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006507 // GPI anchor release // inferred from direct assay /// 0006507 // GPI anchor release // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010897 // negative regulation of triglyceride catabolic process // inferred from sequence or structural similarity /// 0010907 // positive regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035701 // hematopoietic stem cell migration // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071401 // cellular response to triglyceride // inferred from mutant phenotype /// 0071467 // cellular response to pH // inferred from direct assay /// 0097241 // hematopoietic stem cell migration to bone marrow // traceable author statement /// 1900076 // regulation of cellular response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004621 // glycosylphosphatidylinositol phospholipase D activity // inferred from direct assay /// 0004621 // glycosylphosphatidylinositol phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity 215555_at AU158442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158442 /FEA=EST /DB_XREF=gi:11019963 /DB_XREF=est:AU158442 /CLONE=PLACE2000394 /UG=Hs.273099 Homo sapiens cDNA FLJ13712 fis, clone PLACE2000394 AU158442 215556_at AK023774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023774.1 /DEF=Homo sapiens cDNA FLJ13712 fis, clone PLACE2000394. /FEA=mRNA /DB_XREF=gi:10435808 /UG=Hs.273099 Homo sapiens cDNA FLJ13712 fis, clone PLACE2000394 AK023774 215557_at AU144900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144900 /FEA=EST /DB_XREF=gi:11006421 /DB_XREF=est:AU144900 /CLONE=HEMBA1003327 /UG=Hs.274233 Homo sapiens cDNA FLJ10146 fis, clone HEMBA1003327 AU144900 215558_at AK001118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001118.1 /DEF=Homo sapiens cDNA FLJ10256 fis, clone HEMBB1000870. /FEA=mRNA /DB_XREF=gi:7022179 /UG=Hs.274277 Homo sapiens cDNA FLJ10256 fis, clone HEMBB1000870 AK001118 ubiquitin protein ligase E3 component n-recognin 2 UBR2 23304 NM_001184801 /// NM_015255 /// XM_005248965 /// XM_005248966 0006342 // chromatin silencing // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0033522 // histone H2A ubiquitination // inferred from sequence or structural similarity /// 0071233 // cellular response to leucine // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070728 // leucine binding // inferred from direct assay 215559_at AI074459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI074459 /FEA=EST /DB_XREF=gi:3401103 /DB_XREF=est:oy96f06.x1 /CLONE=IMAGE:1673699 /UG=Hs.274260 ATP-binding cassette, sub-family C (CFTRMRP), member 6 AI074459 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 /// multidrug resistance-associated protein 6-like ABCC6 /// LOC101930322 368 /// 101930322 NM_001079528 /// NM_001171 /// XM_005255310 /// XM_005276048 /// XM_006725193 /// XM_006725194 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 215560_x_at AU145135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145135 /FEA=EST /DB_XREF=gi:11006656 /DB_XREF=est:AU145135 /CLONE=HEMBA1003989 /UG=Hs.274266 Homo sapiens cDNA FLJ10175 fis, clone HEMBA1003989 AU145135 mitochondrial translational release factor 1-like MTRF1L 54516 NM_001114184 /// NM_019041 /// XM_005267035 /// XM_005267036 /// XM_005267037 /// XR_245540 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0003747 // translation release factor activity // inferred from electronic annotation /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation 215561_s_at AK026803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026803.1 /DEF=Homo sapiens cDNA: FLJ23150 fis, clone LNG09358. /FEA=mRNA /DB_XREF=gi:10439742 /UG=Hs.277176 Homo sapiens cDNA: FLJ23150 fis, clone LNG09358 AK026803 interleukin 1 receptor, type I IL1R1 3554 NM_000877 /// NM_001288706 /// XM_005263929 /// XM_005263930 /// XM_005263931 /// XM_005263932 /// XM_005263933 /// XM_005263934 /// XR_244889 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0002020 // protease binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from direct assay /// 0004909 // interleukin-1, Type I, activating receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 215562_at AK000220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000220.1 /DEF=Homo sapiens cDNA FLJ20213 fis, clone COLF1971, highly similar to AB007921 Homo sapiens mRNA for KIAA0452 protein. /FEA=mRNA /DB_XREF=gi:7020162 /UG=Hs.274320 Homo sapiens cDNA FLJ20213 fis, clone COLF1971, highly similar to AB007921 Homo sapiens mRNA for KIAA0452 protein AK000220 tetratricopeptide repeat domain 39A TTC39A 22996 NM_001080494 /// NM_001144832 /// XM_005270641 /// XM_005270643 /// XM_005270644 /// XM_005270645 /// XM_005270646 /// XM_006710471 215563_s_at U28055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U28055.1 /DEF=Homo sapiens hepatocyte growth factor-like protein homolog mRNA, partial cds. /FEA=mRNA /PROD=hepatocyte growth factor-like protein homolog /DB_XREF=gi:1141776 /UG=Hs.278657 macrophage stimulating 1 (hepatocyte growth factor-like) U28055 macrophage stimulating 1-like MST1L 11223 NM_001271733 /// NR_002729 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215564_at AV652031 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV652031 /FEA=EST /DB_XREF=gi:9873045 /DB_XREF=est:AV652031 /CLONE=GLCCWA12 /UG=Hs.282344 Homo sapiens cDNA FLJ13387 fis, clone PLACE1001136 AV652031 amphiregulin AREG 374 NM_001657 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 215565_at AK022277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022277.1 /DEF=Homo sapiens cDNA FLJ12215 fis, clone MAMMA1001021. /FEA=mRNA /DB_XREF=gi:10433636 /UG=Hs.282262 Homo sapiens cDNA FLJ12215 fis, clone MAMMA1001021 AK022277 uncharacterized LOC101929272 LOC101929272 101929272 XR_244976 /// XR_249102 /// XR_251047 /// XR_425382 /// XR_427012 /// XR_431405 215566_x_at AK024724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024724.1 /DEF=Homo sapiens cDNA: FLJ21071 fis, clone CAS01789, highly similar to AF098668 Homo sapiens acyl-protein thioesterase mRNA. /FEA=mRNA /DB_XREF=gi:10437080 /UG=Hs.283655 lysophospholipase II AK024724 lysophospholipase II LYPLA2 11313 NM_007260 /// XM_005245728 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 215567_at AU144919 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144919 /FEA=EST /DB_XREF=gi:11006440 /DB_XREF=est:AU144919 /CLONE=HEMBA1003384 /UG=Hs.287426 Homo sapiens cDNA FLJ11574 fis, clone HEMBA1003384 AU144919 FCF1 rRNA-processing protein FCF1 51077 NM_015962 /// XM_005267730 /// XM_005267731 /// XR_245689 /// XR_245690 /// XR_245691 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 215568_x_at AL031295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031295 /DEF=Human DNA sequence from clone 886K2 on chromosome 1p35.1-36.12 Contains elongin A (RNA polymerase II elongation factor), hydroxymethylglutaryl-CoA lyase, GALE (UDP-galactose-4-epimerase) ESTs, GSS, STS, CpG island /FEA=mRNA_2 /DB_XREF=gi:4376011 /UG=Hs.283655 lysophospholipase II AL031295 lysophospholipase II LYPLA2 11313 NM_007260 /// XM_005245728 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 215569_at AC004883 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004883 /DEF=Homo sapiens PAC clone RP4-771P4 from 7q11.21-q11.23 /FEA=CDS_1 /DB_XREF=gi:4263746 /UG=Hs.283912 Homo sapiens PAC clone RP4-771P4 from 7q11.21-q11.23 AC004883 GTF2I repeat domain containing 2B GTF2IRD2B 389524 NM_001003795 /// XM_005277579 /// XM_005277580 /// XM_005277581 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation 215570_s_at AC005614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005614 /DEF=Homo sapiens chromosome 19, cosmid F23269 /FEA=CDS /DB_XREF=gi:3540175 /UG=Hs.287391 Homo sapiens chromosome 19, cosmid F23269 AC005614 zinc finger protein 780A /// zinc finger protein 780B ZNF780A /// ZNF780B 163131 /// 284323 NM_001005851 /// NM_001010880 /// NM_001142577 /// NM_001142578 /// NM_001142579 /// XM_005258590 /// XM_005258591 /// XM_005258592 /// XM_005258593 /// XM_005258595 /// XM_005258773 /// XM_005258774 /// XM_005258775 /// XM_006723072 /// XM_006723073 /// XM_006723150 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215571_at AK021495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021495.1 /DEF=Homo sapiens cDNA FLJ11433 fis, clone HEMBA1001121. /FEA=mRNA /DB_XREF=gi:10432690 /UG=Hs.287415 Homo sapiens cDNA FLJ11433 fis, clone HEMBA1001121 AK021495 215572_at AL109708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109708.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 254679. /FEA=mRNA /DB_XREF=gi:5689825 /UG=Hs.284310 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 254679 AL109708 215573_at AU147084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147084 /FEA=EST /DB_XREF=gi:11008605 /DB_XREF=est:AU147084 /CLONE=HEMBB1002371 /UG=Hs.287482 Homo sapiens cDNA FLJ12072 fis, clone HEMBB1002371 AU147084 catalase CAT 847 NM_001752 0000302 // response to reactive oxygen species // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042697 // menopause // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0004096 // catalase activity // inferred from direct assay /// 0004096 // catalase activity // traceable author statement /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay 215574_at AU144294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144294 /FEA=EST /DB_XREF=gi:11005815 /DB_XREF=est:AU144294 /CLONE=HEMBA1001463 /UG=Hs.288590 Homo sapiens cDNA FLJ11454 fis, clone HEMBA1001463 AU144294 215575_at AU157078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157078 /FEA=EST /DB_XREF=gi:11018599 /DB_XREF=est:AU157078 /CLONE=PLACE1006017 /UG=Hs.287580 Homo sapiens cDNA FLJ13526 fis, clone PLACE1006017 AU157078 phosphodiesterase 4D interacting protein PDE4DIP 9659 NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_001195260 /// NM_001195261 /// NM_001198832 /// NM_001198834 /// NM_014644 /// NM_022359 /// XM_005272981 /// XM_005277442 /// XM_005277443 /// XM_005277446 /// XM_006711642 /// XM_006711643 /// XM_006711644 /// XM_006711645 /// XM_006711646 /// XM_006711647 /// XM_006711648 /// XM_006711649 /// XM_006711650 /// XM_006711651 /// XM_006711652 /// XM_006711653 /// XM_006711654 /// XM_006711655 /// XM_006711656 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity 215576_at AU146809 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146809 /FEA=EST /DB_XREF=gi:11008330 /DB_XREF=est:AU146809 /CLONE=HEMBB1001564 /UG=Hs.287476 Homo sapiens cDNA FLJ12004 fis, clone HEMBB1001564, moderately similar to VACUOLAR ATP SYNTHASE SUBUNIT H (EC 3.6.1.34) AU146809 215577_at AU146791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146791 /FEA=EST /DB_XREF=gi:11008312 /DB_XREF=est:AU146791 /CLONE=HEMBB1001531 /UG=Hs.287474 Homo sapiens cDNA FLJ12000 fis, clone HEMBB1001531 AU146791 215578_at AU145365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145365 /FEA=EST /DB_XREF=gi:11006886 /DB_XREF=est:AU145365 /CLONE=HEMBA1004629 /UG=Hs.287437 Homo sapiens cDNA FLJ11662 fis, clone HEMBA1004629 AU145365 215579_at AK022802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022802.1 /DEF=Homo sapiens cDNA FLJ12740 fis, clone NT2RP2000523, weakly similar to APOLIPOPROTEIN B MRNA EDITING PROTEIN. /FEA=mRNA /DB_XREF=gi:10434413 /UG=Hs.287542 Homo sapiens cDNA FLJ12740 fis, clone NT2RP2000523, weakly similar to APOLIPOPROTEIN B MRNA EDITING PROTEIN AK022802 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G APOBEC3G 60489 NM_021822 /// XM_006724290 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016553 // base conversion or substitution editing // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030895 // apolipoprotein B mRNA editing enzyme complex // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from direct assay 215580_at AK022303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022303.1 /DEF=Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274. /FEA=mRNA /DB_XREF=gi:10433670 /UG=Hs.287503 Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274 AK022303 minichromosome maintenance complex component 3 associated protein MCM3AP 8888 NM_003906 /// XM_005261203 /// XM_005261204 /// XM_005261205 /// XM_005261206 /// XM_006724064 /// XM_006724065 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215581_s_at AK022303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022303.1 /DEF=Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274. /FEA=mRNA /DB_XREF=gi:10433670 /UG=Hs.287503 Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274 AK022303 minichromosome maintenance complex component 3 associated protein MCM3AP 8888 NM_003906 /// XM_005261203 /// XM_005261204 /// XM_005261205 /// XM_005261206 /// XM_006724064 /// XM_006724065 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215582_x_at AK022303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022303.1 /DEF=Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274. /FEA=mRNA /DB_XREF=gi:10433670 /UG=Hs.287503 Homo sapiens cDNA FLJ12241 fis, clone MAMMA1001274 AK022303 minichromosome maintenance complex component 3 associated protein MCM3AP 8888 NM_003906 /// XM_005261203 /// XM_005261204 /// XM_005261205 /// XM_005261206 /// XM_006724064 /// XM_006724065 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215583_at AU148184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148184 /FEA=EST /DB_XREF=gi:11009705 /DB_XREF=est:AU148184 /CLONE=MAMMA1002820 /UG=Hs.287529 Homo sapiens cDNA FLJ12403 fis, clone MAMMA1002820 AU148184 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 215584_at AK022679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022679.1 /DEF=Homo sapiens cDNA FLJ12617 fis, clone NT2RM4001662. /FEA=mRNA /DB_XREF=gi:10434213 /UG=Hs.287538 Homo sapiens cDNA FLJ12617 fis, clone NT2RM4001662 AK022679 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 HECW1 23072 NM_001287059 /// NM_015052 /// XM_005249665 /// XM_006715670 /// XM_006715671 /// XM_006715672 /// XM_006715673 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 215585_at AK024081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024081.1 /DEF=Homo sapiens cDNA FLJ14019 fis, clone HEMBA1002503. /FEA=mRNA /DB_XREF=gi:10436370 /UG=Hs.287613 Homo sapiens cDNA FLJ14019 fis, clone HEMBA1002503 AK024081 215586_at AK024173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024173.1 /DEF=Homo sapiens cDNA FLJ14111 fis, clone MAMMA1001630. /FEA=mRNA /DB_XREF=gi:10436489 /UG=Hs.288567 Homo sapiens cDNA FLJ14111 fis, clone MAMMA1001630 AK024173 215587_x_at AK023891 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023891.1 /DEF=Homo sapiens cDNA FLJ13829 fis, clone THYRO1000625. /FEA=mRNA /DB_XREF=gi:10435964 /UG=Hs.287600 Homo sapiens cDNA FLJ13829 fis, clone THYRO1000625 AK023891 215588_x_at AK024958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024958.1 /DEF=Homo sapiens cDNA: FLJ21305 fis, clone COL02124. /FEA=mRNA /DB_XREF=gi:10437382 /UG=Hs.287658 Homo sapiens cDNA: FLJ21305 fis, clone COL02124 AK024958 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215589_at AK024937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024937.1 /DEF=Homo sapiens cDNA: FLJ21284 fis, clone COL01911. /FEA=mRNA /DB_XREF=gi:10437358 /UG=Hs.288218 Homo sapiens cDNA: FLJ21284 fis, clone COL01911 AK024937 215590_x_at AK025619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025619.1 /DEF=Homo sapiens cDNA: FLJ21966 fis, clone HEP05644. /FEA=mRNA /DB_XREF=gi:10438192 /UG=Hs.287688 Homo sapiens cDNA: FLJ21966 fis, clone HEP05644 AK025619 ACVR2B antisense RNA 1 ACVR2B-AS1 100128640 NR_028389 215591_at AK025127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025127.1 /DEF=Homo sapiens cDNA: FLJ21474 fis, clone COL04941. /FEA=mRNA /DB_XREF=gi:10437581 /UG=Hs.287668 Homo sapiens cDNA: FLJ21474 fis, clone COL04941 AK025127 SATB homeobox 2 SATB2 23314 NM_001172509 /// NM_001172517 /// NM_015265 /// XM_005246396 /// XM_006712372 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 215592_at AU147620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147620 /FEA=EST /DB_XREF=gi:11009141 /DB_XREF=est:AU147620 /CLONE=MAMMA1001206 /UG=Hs.288490 Homo sapiens cDNA FLJ12232 fis, clone MAMMA1001206 AU147620 215593_at AK023918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023918.1 /DEF=Homo sapiens cDNA FLJ13856 fis, clone THYRO1000988. /FEA=mRNA /DB_XREF=gi:10436003 /UG=Hs.288489 Homo sapiens cDNA FLJ13856 fis, clone THYRO1000988 AK023918 215594_at AU148611 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148611 /FEA=EST /DB_XREF=gi:11010132 /DB_XREF=est:AU148611 /CLONE=NT2RM4000607 /UG=Hs.296832 Human pTR7 mRNA for repetitive sequence AU148611 endogenous retrovirus group 9, member 1 ERV9-1 100616497 215595_x_at AK023918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023918.1 /DEF=Homo sapiens cDNA FLJ13856 fis, clone THYRO1000988. /FEA=mRNA /DB_XREF=gi:10436003 /UG=Hs.288489 Homo sapiens cDNA FLJ13856 fis, clone THYRO1000988 AK023918 215596_s_at AL163248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL163248 /DEF=Homo sapiens chromosome 21 segment HS21C048 /FEA=mRNA_2 /DB_XREF=gi:7717304 /UG=Hs.288773 zinc finger protein 294 AL163248 listerin E3 ubiquitin protein ligase 1 LTN1 26046 NM_015565 /// XM_006723987 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215597_x_at AU143799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU143799 /FEA=EST /DB_XREF=gi:11005320 /DB_XREF=est:AU143799 /CLONE=HEMBA1000042 /UG=Hs.288956 Homo sapiens cDNA FLJ11353 fis, clone HEMBA1000042 AU143799 215598_at AK027161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027161.1 /DEF=Homo sapiens cDNA: FLJ23508 fis, clone LNG03158. /FEA=mRNA /DB_XREF=gi:10440220 /UG=Hs.288772 Homo sapiens cDNA: FLJ23508 fis, clone LNG03158 AK027161 tetratricopeptide repeat domain 12 TTC12 54970 NM_017868 /// XM_005271603 /// XM_005271604 /// XM_005271605 /// XM_005271606 /// XM_005271607 /// XM_006718866 215599_at X83300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83300.1 /DEF=H.sapiens SMA4 mRNA. /FEA=mRNA /GEN=SMA4 /DB_XREF=gi:603028 /UG=Hs.289103 SMA4 X83300 glucuronidase, beta pseudogene 3 /// glucuronidase, beta pseudogene 9 GUSBP3 /// GUSBP9 653188 /// 100049076 NR_027386 /// NR_033968 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 215600_x_at AK022174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022174.1 /DEF=Homo sapiens cDNA FLJ12112 fis, clone MAMMA1000043. /FEA=mRNA /DB_XREF=gi:10433510 /UG=Hs.288793 Homo sapiens cDNA FLJ12112 fis, clone MAMMA1000043 AK022174 F-box and WD repeat domain containing 12 FBXW12 285231 NM_001159927 /// NM_001159929 /// NM_207102 /// XR_245120 215601_at AU159040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159040 /FEA=EST /DB_XREF=gi:11020561 /DB_XREF=est:AU159040 /CLONE=THYRO1000676 /UG=Hs.296745 Homo sapiens cDNA FLJ13833 fis, clone THYRO1000676 AU159040 215602_at AK024456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024456.1 /DEF=Homo sapiens mRNA for FLJ00048 protein, partial cds. /FEA=mRNA /GEN=FLJ00048 /PROD=FLJ00048 protein /DB_XREF=gi:10440425 /UG=Hs.289034 Homo sapiens mRNA for FLJ00048 protein, partial cds AK024456 FYVE, RhoGEF and PH domain containing 2 FGD2 221472 NM_173558 /// XM_005248911 /// XM_005248912 /// XM_005248913 /// XM_005248914 /// XM_006715016 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0046847 // filopodium assembly // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215603_x_at AI344075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI344075 /FEA=EST /DB_XREF=gi:4081281 /DB_XREF=est:tb87f08.x1 /CLONE=IMAGE:2061351 /UG=Hs.289098 gamma-glutamyltransferase 2 AI344075 gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 2 /// gamma-glutamyltransferase 3 pseudogene /// gamma-glutamyltransferase light chain 1 /// gamma-glutamyltransferase light chain 2 /// immunoglobulin superfamily member 3-like /// gamma-glutamyltranspeptidase 2-like GGT1 /// GGT2 /// GGT3P /// GGTLC1 /// GGTLC2 /// LOC100132705 /// LOC102724197 2678 /// 2679 /// 91227 /// 92086 /// 728441 /// 100132705 /// 102724197 NM_001032364 /// NM_001032365 /// NM_001282879 /// NM_001288833 /// NM_005265 /// NM_013421 /// NM_013430 /// NM_080839 /// NM_080920 /// NM_178311 /// NM_178312 /// NM_199127 /// NR_003267 /// XM_005260863 /// XM_005260864 /// XM_005260865 /// XM_005261815 /// XM_005261817 /// XM_005261818 /// XM_005261888 /// XM_005261890 /// XM_006723661 /// XM_006723662 /// XM_006724365 /// XM_006724366 /// XM_006724367 /// XM_006724368 /// XM_006724392 /// XM_006724393 /// XM_006724394 /// XM_006724395 /// XM_006724396 /// XM_006724397 /// XM_006724913 /// XM_006724914 /// XM_006724915 /// XM_006724916 /// XM_006724917 /// XM_006724918 /// XM_006724919 /// XM_006724920 /// XM_006724921 /// XM_006724922 /// XM_006724923 /// XM_006724924 /// XM_006724925 /// XM_006724926 /// XM_006724927 /// XM_006724928 /// XM_006724929 /// XM_006724930 /// XM_006726820 /// XM_006726826 /// XR_426489 /// XR_430593 0002682 // regulation of immune system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // non-traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from sequence or structural similarity /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006751 // glutathione catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0019344 // cysteine biosynthetic process // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from mutant phenotype /// 0019370 // leukotriene biosynthetic process // inferred from sequence or structural similarity /// 0031638 // zymogen activation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003840 // gamma-glutamyltransferase activity // inferred from direct assay /// 0003840 // gamma-glutamyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036374 // glutathione hydrolase activity // inferred from direct assay /// 0036374 // glutathione hydrolase activity // inferred from electronic annotation 215604_x_at AK023783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023783.1 /DEF=Homo sapiens cDNA FLJ13721 fis, clone PLACE2000450. /FEA=mRNA /DB_XREF=gi:10435820 /UG=Hs.289035 Homo sapiens cDNA FLJ13721 fis, clone PLACE2000450 AK023783 215605_at AU145806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145806 /FEA=EST /DB_XREF=gi:11007327 /DB_XREF=est:AU145806 /CLONE=HEMBA1005894 /UG=Hs.296664 Homo sapiens cDNA FLJ11776 fis, clone HEMBA1005894 AU145806 nuclear receptor coactivator 2 NCOA2 10499 NM_006540 /// XM_005251128 /// XM_005251129 /// XM_005251130 /// XM_005251131 /// XM_005251132 /// XM_005251133 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from reviewed computational analysis /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 215606_s_at AB029004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029004.1 /DEF=Homo sapiens mRNA for KIAA1081 protein, partial cds. /FEA=mRNA /GEN=KIAA1081 /PROD=KIAA1081 protein /DB_XREF=gi:5689498 /UG=Hs.293705 KIAA1081 protein AB029004 ELKS/RAB6-interacting/CAST family member 1 ERC1 23085 NM_178039 /// NM_178040 /// NR_027946 /// NR_027948 /// NR_027949 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0007275 // multicellular organismal development // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0043522 // leucine zipper domain binding // non-traceable author statement 215607_x_at AU144530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144530 /FEA=EST /DB_XREF=gi:11006051 /DB_XREF=est:AU144530 /CLONE=HEMBA1002189 /UG=Hs.296654 Homo sapiens cDNA FLJ11511 fis, clone HEMBA1002189 AU144530 215608_at AU144378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144378 /FEA=EST /DB_XREF=gi:11005899 /DB_XREF=est:AU144378 /CLONE=HEMBA1001734 /UG=Hs.296650 Homo sapiens cDNA FLJ11475 fis, clone HEMBA1001734, moderately similar to CADHERIN-11 PRECURSOR AU144378 Homo sapiens cDNA FLJ11475 fis, clone HEMBA1001734, moderately similar to CADHERIN-11 PRECURSOR. AK021537 215609_at AK023895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023895.1 /DEF=Homo sapiens cDNA FLJ13833 fis, clone THYRO1000676. /FEA=mRNA /DB_XREF=gi:10435969 /UG=Hs.296745 Homo sapiens cDNA FLJ13833 fis, clone THYRO1000676 AK023895 215610_at AK022038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022038.1 /DEF=Homo sapiens cDNA FLJ11976 fis, clone HEMBB1001253. /FEA=mRNA /DB_XREF=gi:10433356 /UG=Hs.296679 Homo sapiens cDNA FLJ11976 fis, clone HEMBB1001253 AK022038 215611_at AU146580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146580 /FEA=EST /DB_XREF=gi:11008101 /DB_XREF=est:AU146580 /CLONE=HEMBB1000893 /UG=Hs.296677 Homo sapiens cDNA FLJ11956 fis, clone HEMBB1000893 AU146580 transcription factor 12 TCF12 6938 NM_003205 /// NM_207036 /// NM_207037 /// NM_207038 /// NM_207040 /// XM_005254613 /// XM_006720658 /// XM_006720659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from electronic annotation 215612_at AU147983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147983 /FEA=EST /DB_XREF=gi:11009504 /DB_XREF=est:AU147983 /CLONE=MAMMA1002308 /UG=Hs.296716 Homo sapiens cDNA FLJ12349 fis, clone MAMMA1002308 AU147983 215613_at AU145357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145357 /FEA=EST /DB_XREF=gi:11006878 /DB_XREF=est:AU145357 /CLONE=HEMBA1004611 /UG=Hs.296700 Homo sapiens cDNA FLJ12134 fis, clone MAMMA1000287 AU145357 ADAM metallopeptidase domain 12 ADAM12 8038 NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007520 // myoblast fusion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215614_at AK022038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022038.1 /DEF=Homo sapiens cDNA FLJ11976 fis, clone HEMBB1001253. /FEA=mRNA /DB_XREF=gi:10433356 /UG=Hs.296679 Homo sapiens cDNA FLJ11976 fis, clone HEMBB1001253 AK022038 215615_x_at AU148274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148274 /FEA=EST /DB_XREF=gi:11009795 /DB_XREF=est:AU148274 /CLONE=MAMMA1003089 /UG=Hs.301201 Homo sapiens cDNA FLJ14152 fis, clone MAMMA1003089 AU148274 215616_s_at AB020683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020683.1 /DEF=Homo sapiens mRNA for KIAA0876 protein, partial cds. /FEA=mRNA /GEN=KIAA0876 /PROD=KIAA0876 protein /DB_XREF=gi:4240240 /UG=Hs.301011 KIAA0876 protein AB020683 lysine (K)-specific demethylase 4B KDM4B 23030 NM_015015 /// XM_005259521 /// XM_005259522 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 215617_at AU145711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145711 /FEA=EST /DB_XREF=gi:11007232 /DB_XREF=est:AU145711 /CLONE=HEMBA1005588 /UG=Hs.301006 Homo sapiens cDNA FLJ11754 fis, clone HEMBA1005588 AU145711 spermatogenesis associated, serine-rich 2-like SPATS2L 26010 NM_001100422 /// NM_001100423 /// NM_001100424 /// NM_001282735 /// NM_001282743 /// NM_001282744 /// NM_015535 /// XM_005246454 /// XM_005246456 /// XM_005246457 /// XM_005246458 /// XM_005246459 /// XM_005246460 /// XM_006712409 /// XM_006712410 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215618_at AK024109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024109.1 /DEF=Homo sapiens cDNA FLJ14047 fis, clone HEMBA1006617. /FEA=mRNA /DB_XREF=gi:10436407 /UG=Hs.301186 Homo sapiens cDNA FLJ14047 fis, clone HEMBA1006617 AK024109 Ras suppressor protein 1 RSU1 6251 NM_012425 /// NM_152724 /// XM_005252552 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215619_at AK024214 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024214.1 /DEF=Homo sapiens cDNA FLJ14152 fis, clone MAMMA1003089. /FEA=mRNA /DB_XREF=gi:10436536 /UG=Hs.301201 Homo sapiens cDNA FLJ14152 fis, clone MAMMA1003089 AK024214 215620_at AU147182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147182 /FEA=EST /DB_XREF=gi:11008703 /DB_XREF=est:AU147182 /CLONE=HEMBB1002623 /UG=Hs.301197 Homo sapiens cDNA FLJ12098 fis, clone HEMBB1002623 AU147182 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215621_s_at BG340670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG340670 /FEA=EST /DB_XREF=gi:13147108 /DB_XREF=est:602462250F1 /CLONE=IMAGE:4574941 /UG=Hs.301365 Human rearranged immunoglobulin heavy chain mRNA, partial cds BG340670 immunoglobulin heavy constant delta IGHD 3495 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 215622_x_at AL137671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137671.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L1850 (from clone DKFZp434L1850); partial cds. /FEA=mRNA /GEN=DKFZp434L1850 /PROD=hypothetical protein /DB_XREF=gi:6807837 /UG=Hs.30127 hypothetical protein AL137671 PHD finger protein 7 PHF7 51533 NM_001278221 /// NM_016483 /// NM_173341 /// XM_005265225 /// XM_005265226 /// XM_005265227 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215623_x_at AK002200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002200.1 /DEF=Homo sapiens cDNA FLJ11338 fis, clone PLACE1010720, highly similar to Homo sapiens mRNA for chromosome-associated polypeptide-C. /FEA=mRNA /DB_XREF=gi:7023928 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 AK002200 structural maintenance of chromosomes 4 SMC4 10051 NM_001002799 /// NM_001002800 /// NM_001288753 /// NM_005496 /// XM_006713459 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 215624_at AU147962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147962 /FEA=EST /DB_XREF=gi:11009483 /DB_XREF=est:AU147962 /CLONE=MAMMA1002250 /UG=Hs.301509 Homo sapiens cDNA FLJ12339 fis, clone MAMMA1002250 AU147962 tuberous sclerosis 2 TSC2 7249 NM_000548 /// NM_001077183 /// NM_001114382 /// NM_021055 /// NM_021056 /// XM_005255527 /// XM_005255528 /// XM_005255529 /// XM_005255530 /// XM_005255531 /// XM_005255532 0001666 // response to hypoxia // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from sequence or structural similarity /// 0006897 // endocytosis // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // not recorded /// 0032007 // negative regulation of TOR signaling // not recorded /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0046626 // regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // not recorded /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // not recorded /// 0051898 // negative regulation of protein kinase B signaling // not recorded /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0033596 // TSC1-TSC2 complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 215625_at AK001448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001448.1 /DEF=Homo sapiens cDNA FLJ10586 fis, clone NT2RP2003986. /FEA=mRNA /DB_XREF=gi:7022713 /UG=Hs.301255 Homo sapiens cDNA FLJ10586 fis, clone NT2RP2003986 AK001448 uncharacterized LOC101928669 /// uncharacterized LOC644450 LOC101928669 /// LOC644450 644450 /// 101928669 XM_927590 /// XR_247336 /// XR_424062 /// XR_424063 /// XR_424064 /// XR_424065 215626_at AU144887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144887 /FEA=EST /DB_XREF=gi:11006408 /DB_XREF=est:AU144887 /CLONE=HEMBA1003278 /UG=Hs.301800 Homo sapiens cDNA FLJ11568 fis, clone HEMBA1003278 AU144887 215627_at AK023515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023515.1 /DEF=Homo sapiens cDNA FLJ13453 fis, clone PLACE1003205. /FEA=mRNA /DB_XREF=gi:10435471 /UG=Hs.301715 Homo sapiens cDNA FLJ13453 fis, clone PLACE1003205 AK023515 uncharacterized LOC101926913 LOC101926913 101926913 NR_110185 215628_x_at AL049285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049285.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M193 (from clone DKFZp564M193). /FEA=mRNA /DB_XREF=gi:4500045 /UG=Hs.302053 Homo sapiens mRNA; cDNA DKFZp564M193 (from clone DKFZp564M193) AL049285 215629_s_at AA905286 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA905286 /FEA=EST /DB_XREF=gi:3040409 /DB_XREF=est:oj96b09.s1 /CLONE=IMAGE:1506137 /UG=Hs.306636 BCMS-upstream neighbor-like (BCMSUNL) AA905286 deleted in lymphocytic leukemia 2 (non-protein coding) /// deleted in lymphocytic leukemia 2-like /// microRNA 15a DLEU2 /// DLEU2L /// MIR15A 8847 /// 79469 /// 406948 NR_002612 /// NR_002771 /// NR_029485 215630_at AU147528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147528 /FEA=EST /DB_XREF=gi:11009049 /DB_XREF=est:AU147528 /CLONE=MAMMA1000940 /UG=Hs.301811 Homo sapiens cDNA FLJ14102 fis, clone MAMMA1000940 AU147528 215631_s_at AL050008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050008.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A063 (from clone DKFZp564A063); partial cds. /FEA=mRNA /GEN=DKFZp564A063 /PROD=hypothetical protein /DB_XREF=gi:4884078 /UG=Hs.306186 DKFZP564A063 protein AL050008 breast cancer metastasis suppressor 1 BRMS1 25855 NM_001024957 /// NM_001024958 /// NM_015399 /// XM_005273883 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090312 // positive regulation of protein deacetylation // inferred from direct assay /// 2000210 // positive regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from direct assay 215632_at AF303002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF303002 /DEF=Homo sapiens neurogenin 2 gene, partial cds /FEA=CDS /DB_XREF=gi:11875763 /UG=Hs.302165 neurogenin 2 AF303002 neurogenin 2 NEUROG2 63973 NM_024019 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 215633_x_at AV713720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV713720 /FEA=EST /DB_XREF=gi:10795237 /DB_XREF=est:AV713720 /CLONE=DCBBJA12 /UG=Hs.306434 Homo sapiens mRNA for LST-1N protein AV713720 leukocyte specific transcript 1 LST1 7940 NM_001166538 /// NM_007161 /// NM_205837 /// NM_205838 /// NM_205839 /// NM_205840 /// NR_029461 /// NR_029462 /// XM_006715206 /// XM_006715207 /// XM_006715208 /// XM_006715209 /// XM_006715210 /// XM_006715211 /// XM_006725043 /// XM_006725044 /// XM_006725045 /// XM_006725046 /// XM_006725047 /// XM_006725048 /// XM_006725049 /// XM_006725522 /// XM_006725523 /// XM_006725524 /// XM_006725525 /// XM_006725526 /// XM_006725527 /// XM_006725740 /// XM_006725741 /// XM_006725742 /// XM_006725743 /// XM_006725744 /// XM_006725745 /// XM_006725746 /// XM_006725848 /// XM_006725849 /// XM_006725850 /// XM_006725851 /// XM_006725852 /// XM_006725853 /// XM_006725937 /// XM_006725938 /// XM_006725939 /// XM_006725940 /// XM_006725941 /// XM_006725942 /// XM_006726038 /// XM_006726039 /// XM_006726040 /// XM_006726041 /// XM_006726042 /// XM_006726043 /// XM_006726126 /// XM_006726127 /// XM_006726128 /// XM_006726129 /// XM_006726130 /// XM_006726131 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0050672 // negative regulation of lymphocyte proliferation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 215634_at AF007137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007137.1 /DEF=Homo sapiens clone 23618 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852612 /UG=Hs.302185 Homo sapiens clone 23618 mRNA sequence AF007137 215635_at AL109691 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109691.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 239714. /FEA=mRNA /DB_XREF=gi:5689821 /UG=Hs.306330 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 239714 AL109691 215636_at AK022322 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022322.1 /DEF=Homo sapiens cDNA FLJ12260 fis, clone MAMMA1001551. /FEA=mRNA /DB_XREF=gi:10433693 /UG=Hs.306634 Homo sapiens cDNA FLJ12260 fis, clone MAMMA1001551 AK022322 ubiquitin protein ligase E3 component n-recognin 4 UBR4 23352 NM_020765 /// XM_005245802 /// XM_006710503 /// XM_006710504 /// XM_006710505 /// XM_006710506 /// XM_006710507 /// XM_006710508 /// XM_006710509 /// XM_006710510 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215637_at AU155621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU155621 /FEA=EST /DB_XREF=gi:11017142 /DB_XREF=est:AU155621 /CLONE=PLACE1000444 /UG=Hs.306418 Homo sapiens cDNA FLJ10958 fis, clone PLACE1000444 AU155621 centrosomal protein 41kDa CEP41 95681 NM_001257158 /// NM_001257159 /// NM_001257160 /// NM_018718 /// NR_046443 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215638_at U88358 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U88358.1 /DEF=Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial cds. /FEA=mRNA /GEN=c-erbB-3 /PROD=ErbB-3 R2 /DB_XREF=gi:3323390 /UG=Hs.306251 Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial cds U88358 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 ERBB3 2065 NM_001005915 /// NM_001982 0003197 // endocardial cushion development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043235 // receptor complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from sequence or structural similarity /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 215639_at AK000861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000861.1 /DEF=Homo sapiens cDNA FLJ20854 fis, clone ADKA01341. /FEA=mRNA /DB_XREF=gi:7021185 /UG=Hs.306412 Homo sapiens cDNA FLJ20854 fis, clone ADKA01341 AK000861 SH2 domain containing 3C SH2D3C 10044 NM_001142531 /// NM_001142532 /// NM_001142533 /// NM_001142534 /// NM_001252334 /// NM_005489 /// NM_170600 /// XM_005251637 /// XM_005251639 0007254 // JNK cascade // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215640_at AK000173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000173.1 /DEF=Homo sapiens cDNA FLJ20166 fis, clone COL09511. /FEA=mRNA /DB_XREF=gi:7020086 /UG=Hs.306386 Homo sapiens cDNA FLJ20166 fis, clone COL09511 AK000173 TBC1 domain family, member 2B TBC1D2B 23102 NM_015079 /// NM_144572 /// XM_005254242 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215641_at AK000709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000709.1 /DEF=Homo sapiens cDNA FLJ20702 fis, clone KAIA2174. /FEA=mRNA /DB_XREF=gi:7020966 /UG=Hs.306401 Homo sapiens cDNA FLJ20702 fis, clone KAIA2174 AK000709 SEC24 family member D SEC24D 9871 NM_014822 /// XM_005263378 /// XM_005263379 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 215642_at AF090887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090887.1 /DEF=Homo sapiens clone HQ0085. /FEA=mRNA /DB_XREF=gi:6690154 /UG=Hs.306562 Homo sapiens clone HQ0085 AF090887 215643_at AU145680 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145680 /FEA=EST /DB_XREF=gi:11007201 /DB_XREF=est:AU145680 /CLONE=HEMBA1005500 /UG=Hs.306613 Homo sapiens cDNA FLJ11740 fis, clone HEMBA1005500 AU145680 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D SEMA3D 223117 NM_152754 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation 215644_at AF090887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090887.1 /DEF=Homo sapiens clone HQ0085. /FEA=mRNA /DB_XREF=gi:6690154 /UG=Hs.306562 Homo sapiens clone HQ0085 AF090887 zinc finger protein 518A ZNF518A 9849 NM_001278524 /// NM_001278525 /// NM_001278526 /// NM_014803 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215645_at AF090883 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090883.1 /DEF=Homo sapiens clone HQ0021. /FEA=mRNA /DB_XREF=gi:6690149 /UG=Hs.306560 Homo sapiens clone HQ0021 AF090883 folliculin FLCN 201163 NM_144606 /// NM_144997 /// XM_005256515 /// XM_006721470 /// XR_429812 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010823 // negative regulation of mitochondrion organization // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0032006 // regulation of TOR signaling // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032008 // positive regulation of TOR signaling // inferred from sequence or structural similarity /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035065 // regulation of histone acetylation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1900181 // negative regulation of protein localization to nucleus // inferred from direct assay /// 1901723 // negative regulation of cell proliferation involved in kidney development // inferred from sequence or structural similarity /// 2000506 // negative regulation of energy homeostasis // inferred from sequence or structural similarity /// 2000973 // regulation of pro-B cell differentiation // inferred from sequence or structural similarity /// 2001170 // negative regulation of ATP biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay 215646_s_at R94644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R94644 /FEA=EST /DB_XREF=gi:970039 /DB_XREF=est:yq42a12.r1 /CLONE=IMAGE:198430 /UG=Hs.306542 Homo sapiens versican Vint isoform, mRNA, partial cds R94644 versican VCAN 1462 NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385 0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 215647_at AK021576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021576.1 /DEF=Homo sapiens cDNA FLJ11514 fis, clone HEMBA1002229. /FEA=mRNA /DB_XREF=gi:10432783 /UG=Hs.306602 Homo sapiens cDNA FLJ11514 fis, clone HEMBA1002229 AK021576 215648_at AU144324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144324 /FEA=EST /DB_XREF=gi:11005845 /DB_XREF=est:AU144324 /CLONE=HEMBA1001570 /UG=Hs.306599 Homo sapiens cDNA FLJ11461 fis, clone HEMBA1001570 AU144324 215649_s_at AF217536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF217536.1 /DEF=Homo sapiens truncated mevalonate kinase mRNA, partial cds, alternatively spliced. /FEA=mRNA /PROD=truncated mevalonate kinase /DB_XREF=gi:9049521 /UG=Hs.306585 Homo sapiens truncated mevalonate kinase mRNA, partial cds, alternatively spliced AF217536 mevalonate kinase MVK 4598 NM_000431 /// NM_001114185 /// XM_005253883 /// XM_005253884 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004496 // mevalonate kinase activity // inferred from direct assay /// 0004496 // mevalonate kinase activity // inferred from mutant phenotype /// 0004496 // mevalonate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 215650_at AK021614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021614.1 /DEF=Homo sapiens cDNA FLJ11552 fis, clone HEMBA1003021. /FEA=mRNA /DB_XREF=gi:10432830 /UG=Hs.306606 Homo sapiens cDNA FLJ11552 fis, clone HEMBA1003021 AK021614 215651_at AK026682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026682.1 /DEF=Homo sapiens cDNA: FLJ23029 fis, clone LNG01883. /FEA=mRNA /DB_XREF=gi:10439589 /UG=Hs.306864 Homo sapiens cDNA: FLJ23029 fis, clone LNG01883 AK026682 215652_at AK024382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024382.1 /DEF=Homo sapiens cDNA FLJ14320 fis, clone PLACE3000455. /FEA=mRNA /DB_XREF=gi:10436754 /UG=Hs.306677 Homo sapiens cDNA FLJ14320 fis, clone PLACE3000455 AK024382 succinate dehydrogenase complex, subunit D, integral membrane protein SDHD 6392 NM_001276503 /// NM_001276504 /// NM_001276506 /// NM_003002 /// NR_077060 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity 215653_at AF339805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339805.1 /DEF=Homo sapiens clone IMAGE:248602, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507343 /UG=Hs.326719 Homo sapiens clone IMAGE:248602, mRNA sequence AF339805 215654_at AK023909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023909.1 /DEF=Homo sapiens cDNA FLJ13847 fis, clone THYRO1000852, highly similar to Human branched-chain amino acid aminotransferase (ECA40) mRNA. /FEA=mRNA /DB_XREF=gi:10435989 /UG=Hs.306660 Homo sapiens cDNA FLJ13847 fis, clone THYRO1000852, highly similar to Human branched-chain amino acid aminotransferase (ECA40) mRNA AK023909 branched chain amino-acid transaminase 2, mitochondrial BCAT2 587 NM_001164773 /// NM_001190 /// NM_001284325 /// NR_028451 0006549 // isoleucine metabolic process // inferred from electronic annotation /// 0006550 // isoleucine catabolic process // inferred from electronic annotation /// 0006551 // leucine metabolic process // inferred from electronic annotation /// 0006573 // valine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0010817 // regulation of hormone levels // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation 215655_at AU156204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU156204 /FEA=EST /DB_XREF=gi:11017725 /DB_XREF=est:AU156204 /CLONE=PLACE1002583 /UG=Hs.306651 Homo sapiens cDNA FLJ13435 fis, clone PLACE1002583, moderately similar to GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 PRECURSOR AU156204 glutamate receptor, ionotropic, kainate 2 GRIK2 2898 NM_001166247 /// NM_021956 /// NM_175768 /// XM_005266945 /// XM_005266946 /// XM_006715465 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from mutant phenotype /// 0050804 // regulation of synaptic transmission // inferred from direct assay /// 0050806 // positive regulation of synaptic transmission // inferred from mutant phenotype /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay 215656_at AK025041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025041.1 /DEF=Homo sapiens cDNA: FLJ21388 fis, clone COL03424. /FEA=mRNA /DB_XREF=gi:10437478 /UG=Hs.306751 Homo sapiens cDNA: FLJ21388 fis, clone COL03424 AK025041 lectin, mannose-binding 2 LMAN2 10960 NM_006816 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from mutant phenotype /// 0030246 // carbohydrate binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215657_at AK025044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025044.1 /DEF=Homo sapiens cDNA: FLJ21391 fis, clone COL03479. /FEA=mRNA /DB_XREF=gi:10437481 /UG=Hs.306752 Homo sapiens cDNA: FLJ21391 fis, clone COL03479 AK025044 solute carrier family 26 (anion exchanger), member 3 SLC26A3 1811 NM_000111 /// XM_006715873 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0097225 // sperm midpiece // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 215658_at AK024897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024897.1 /DEF=Homo sapiens cDNA: FLJ21244 fis, clone COL01174. /FEA=mRNA /DB_XREF=gi:10437311 /UG=Hs.306721 Homo sapiens cDNA: FLJ21244 fis, clone COL01174 AK024897 long intergenic non-protein coding RNA 675 LINC00675 100289255 NR_036581 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215659_at AK025174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025174.1 /DEF=Homo sapiens cDNA: FLJ21521 fis, clone COL05880. /FEA=mRNA /DB_XREF=gi:10437636 /UG=Hs.306777 Homo sapiens cDNA: FLJ21521 fis, clone COL05880 AK025174 gasdermin B GSDMB 55876 NM_001042471 /// NM_001165958 /// NM_001165959 /// NM_018530 /// XM_005257508 /// XM_005257510 /// XM_005257511 /// XM_006721974 0005737 // cytoplasm // inferred from electronic annotation 215660_s_at AK025352 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025352.1 /DEF=Homo sapiens cDNA: FLJ21699 fis, clone COL09829. /FEA=mRNA /DB_XREF=gi:10437851 /UG=Hs.306804 Homo sapiens cDNA: FLJ21699 fis, clone COL09829 AK025352 microtubule associated serine/threonine kinase 2 MAST2 23139 NM_015112 /// XM_005270652 /// XM_005270653 /// XM_005270654 /// XM_005270655 /// XM_005270656 /// XM_005270659 /// XM_006710475 /// XM_006710476 /// XM_006710477 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045075 // regulation of interleukin-12 biosynthetic process // inferred from sequence or structural similarity /// 0048515 // spermatid differentiation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215661_at AK025352 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025352.1 /DEF=Homo sapiens cDNA: FLJ21699 fis, clone COL09829. /FEA=mRNA /DB_XREF=gi:10437851 /UG=Hs.306804 Homo sapiens cDNA: FLJ21699 fis, clone COL09829 AK025352 microtubule associated serine/threonine kinase 2 MAST2 23139 NM_015112 /// XM_005270652 /// XM_005270653 /// XM_005270654 /// XM_005270655 /// XM_005270656 /// XM_005270659 /// XM_006710475 /// XM_006710476 /// XM_006710477 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045075 // regulation of interleukin-12 biosynthetic process // inferred from sequence or structural similarity /// 0048515 // spermatid differentiation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215662_at AK025352 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025352.1 /DEF=Homo sapiens cDNA: FLJ21699 fis, clone COL09829. /FEA=mRNA /DB_XREF=gi:10437851 /UG=Hs.306804 Homo sapiens cDNA: FLJ21699 fis, clone COL09829 AK025352 215663_at BC005296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005296.1 /DEF=Homo sapiens, clone IMAGE:3935812, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3935812) /DB_XREF=gi:13529013 /UG=Hs.326710 Homo sapiens, clone IMAGE:3935812, mRNA, partial cds BC005296 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215664_s_at X95425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95425.1 /DEF=H.sapiens mRNA for EHK-1 receptor tyrosine kinase. /FEA=mRNA /PROD=EHK-1 receptor tyrosine kinase /DB_XREF=gi:1177465 /UG=Hs.31092 EphA5 X95425 EPH receptor A5 EPHA5 2044 NM_001281765 /// NM_001281766 /// NM_001281767 /// NM_004439 /// NM_182472 /// XM_005265653 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032793 // positive regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from expression pattern /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from sequence or structural similarity /// 0005004 // GPI-linked ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215665_at AL359553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359553 /DEF=Human DNA sequence from clone RP5-871G17 on chromosome 1. Contains ESTs, STSs and GSSs. Contains the HAO2 gene for hydroxyacid oxidase 2 (long chain), the HSD3B2 gene for hydroxy-delta-5-steroid dehydrogenase (3 beta-and steroid delta-isomerase 2)... /FEA=mRNA_1 /DB_XREF=gi:9944183 /UG=Hs.307108 Human DNA sequence from clone RP5-871G17 on chromosome 1. Contains ESTs, STSs and GSSs. Contains the HAO2 gene for hydroxyacid oxidase 2 (long chain), the HSD3B2 gene for hydroxy-delta-5-steroid dehydrogenase (3 beta-and steroid delta-isomerase 2), two GA AL359553 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 1, mRNA. HSD3B2 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006705 // mineralocorticoid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030868 // smooth endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from direct assay /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0004769 // steroid delta-isomerase activity // inferred from direct assay /// 0004769 // steroid delta-isomerase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 215666_at U70544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U70544.1 /DEF=Homo sapiens HLA class II DRB4 null antigen (HLA-DRB4) pseudogene mRNA, null allele HLA-DRB4*0201N, partial cds. /FEA=mRNA /GEN=HLA-DRB4 /PROD=MHC class II DRB4 null antigen /DB_XREF=gi:1597725 /UG=Hs.318720 Homo sapiens, clone MGC:12387, mRNA, complete cds U70544 major histocompatibility complex, class II, DR beta 4 HLA-DRB4 3126 NM_021983 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 215667_x_at AI375694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375694 /FEA=EST /DB_XREF=gi:4175684 /DB_XREF=est:ta58f12.x1 /CLONE=IMAGE:2048303 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 AI375694 postmeiotic segregation increased 2 pseudogene 5 /// postmeiotic segregation increased 2 pseudogene 9 PMS2P5 /// PMS2P9 5383 /// 100132832 NM_001129851 /// NM_174930 /// NR_027775 /// NR_027776 /// NR_027777 /// NR_028058 0006298 // mismatch repair // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 215668_s_at AJ011414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ011414.1 /DEF=Homo sapiens mRNA for plexin-B1 plasma membrane receptor, truncated splice variant (plexin-B1SEP gene). /FEA=mRNA /GEN=plexin-B1SEP /PROD=plexin-B1SEP receptor /DB_XREF=gi:5918164 /UG=Hs.312939 Homo sapiens mRNA for plexin-B1 plasma membrane receptor, truncated splice variant (plexin-B1SEP gene) AJ011414 plexin B1 PLXNB1 5364 NM_001130082 /// NM_002673 /// XM_005265234 /// XM_006713206 /// XR_245138 /// XR_427278 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016477 // cell migration // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1900220 // semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // inferred from direct assay /// 0002116 // semaphorin receptor complex // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from direct assay /// 0017154 // semaphorin receptor activity // traceable author statement /// 0030215 // semaphorin receptor binding // traceable author statement /// 0032794 // GTPase activating protein binding // inferred from sequence or structural similarity 215669_at U70544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U70544.1 /DEF=Homo sapiens HLA class II DRB4 null antigen (HLA-DRB4) pseudogene mRNA, null allele HLA-DRB4*0201N, partial cds. /FEA=mRNA /GEN=HLA-DRB4 /PROD=MHC class II DRB4 null antigen /DB_XREF=gi:1597725 /UG=Hs.318720 Homo sapiens, clone MGC:12387, mRNA, complete cds U70544 215670_s_at AK022844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022844.1 /DEF=Homo sapiens cDNA FLJ12782 fis, clone NT2RP2001869, moderately similar to ZINC FINGER PROTEIN 191. /FEA=mRNA /DB_XREF=gi:10434472 /UG=Hs.321696 Homo sapiens cDNA FLJ12782 fis, clone NT2RP2001869, moderately similar to ZINC FINGER PROTEIN 191 AK022844 SCAN domain containing 2 pseudogene SCAND2P 54581 NM_022050 /// NM_033633 /// NM_033634 /// NM_033635 /// NM_033636 /// NM_033640 /// NR_003654 /// NR_004859 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 215671_at AU144792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144792 /FEA=EST /DB_XREF=gi:11006313 /DB_XREF=est:AU144792 /CLONE=HEMBA1002973 /UG=Hs.319540 Homo sapiens cDNA FLJ10127 fis, clone HEMBA1002973, moderately similar to CAMP-DEPENDENT 3,5-CYCLIC PHOSPHODIESTERASE 4B (EC 3.1.4.17) AU144792 phosphodiesterase 4B, cAMP-specific PDE4B 5142 NM_001037339 /// NM_001037340 /// NM_001037341 /// NM_001297440 /// NM_001297441 /// NM_001297442 /// NM_002600 /// XM_005270923 /// XM_005270924 /// XM_005270925 /// XM_005270926 /// XM_006710680 0001780 // neutrophil homeostasis // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215672_s_at AK025372 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025372.1 /DEF=Homo sapiens cDNA: FLJ21719 fis, clone COLF0094. /FEA=mRNA /DB_XREF=gi:10437875 /UG=Hs.4984 KIAA0828 protein AK025372 adenosylhomocysteinase-like 2 AHCYL2 23382 NM_001130720 /// NM_001130722 /// NM_001130723 /// NM_015328 /// XM_005250237 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 215673_at AB051442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051442.1 /DEF=Homo sapiens mRNA for KIAA1655 protein, partial cds. /FEA=mRNA /GEN=KIAA1655 /PROD=KIAA1655 protein /DB_XREF=gi:13359182 /UG=Hs.326759 Homo sapiens mRNA for KIAA1655 protein, partial cds AB051442 thyrotrophic embryonic factor TEF 7008 NM_001145398 /// NM_003216 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215674_at AB051446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051446.1 /DEF=Homo sapiens mRNA for KIAA1659 protein, partial cds. /FEA=mRNA /GEN=KIAA1659 /PROD=KIAA1659 protein /DB_XREF=gi:13359190 /UG=Hs.326758 Homo sapiens mRNA for KIAA1659 protein, partial cds AB051446 215675_at AB051442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051442.1 /DEF=Homo sapiens mRNA for KIAA1655 protein, partial cds. /FEA=mRNA /GEN=KIAA1655 /PROD=KIAA1655 protein /DB_XREF=gi:13359182 /UG=Hs.326759 Homo sapiens mRNA for KIAA1655 protein, partial cds AB051442 215676_at N91109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N91109 /FEA=EST /DB_XREF=gi:1444436 /DB_XREF=est:zb24a03.s1 /CLONE=IMAGE:302956 /UG=Hs.32935 TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 N91109 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit BRF1 2972 NM_001242786 /// NM_001242787 /// NM_001242788 /// NM_001242789 /// NM_001242790 /// NM_001519 /// NM_145685 /// NM_145696 /// XM_005267561 /// XM_005267563 /// XM_006720122 /// XM_006720123 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000126 // transcription factor TFIIIB complex // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215677_s_at N91109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N91109 /FEA=EST /DB_XREF=gi:1444436 /DB_XREF=est:zb24a03.s1 /CLONE=IMAGE:302956 /UG=Hs.32935 TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 N91109 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit BRF1 2972 NM_001242786 /// NM_001242787 /// NM_001242788 /// NM_001242789 /// NM_001242790 /// NM_001519 /// NM_145685 /// NM_145696 /// XM_005267561 /// XM_005267563 /// XM_006720122 /// XM_006720123 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0000126 // transcription factor TFIIIB complex // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215678_at AB051440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051440.1 /DEF=Homo sapiens mRNA for KIAA1653 protein, partial cds. /FEA=mRNA /GEN=KIAA1653 /PROD=KIAA1653 protein /DB_XREF=gi:13359178 /UG=Hs.326761 Homo sapiens mRNA for KIAA1653 protein, partial cds AB051440 proline dehydrogenase (oxidase) 1 pseudogene LOC440792 440792 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006560 // proline metabolic process // inferred from electronic annotation /// 0006560 // proline metabolic process // traceable author statement /// 0006562 // proline catabolic process // inferred from electronic annotation /// 0006562 // proline catabolic process // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004657 // proline dehydrogenase activity // inferred from direct assay /// 0004657 // proline dehydrogenase activity // inferred from electronic annotation /// 0004657 // proline dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 215679_at AL109706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109706.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 362430. /FEA=mRNA /DB_XREF=gi:5689823 /UG=Hs.32769 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 362430 AL109706 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 362430. AL109706 215680_at AB051441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051441.1 /DEF=Homo sapiens mRNA for KIAA1654 protein, partial cds. /FEA=mRNA /GEN=KIAA1654 /PROD=KIAA1654 protein /DB_XREF=gi:13359180 /UG=Hs.326760 Homo sapiens mRNA for KIAA1654 protein, partial cds AB051441 KIAA1654 protein KIAA1654 85368 215681_at AB051441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051441.1 /DEF=Homo sapiens mRNA for KIAA1654 protein, partial cds. /FEA=mRNA /GEN=KIAA1654 /PROD=KIAA1654 protein /DB_XREF=gi:13359180 /UG=Hs.326760 Homo sapiens mRNA for KIAA1654 protein, partial cds AB051441 KIAA1654 protein KIAA1654 85368 215682_at AB051440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051440.1 /DEF=Homo sapiens mRNA for KIAA1653 protein, partial cds. /FEA=mRNA /GEN=KIAA1653 /PROD=KIAA1653 protein /DB_XREF=gi:13359178 /UG=Hs.326761 Homo sapiens mRNA for KIAA1653 protein, partial cds AB051440 proline dehydrogenase (oxidase) 1 pseudogene LOC440792 440792 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006560 // proline metabolic process // inferred from electronic annotation /// 0006560 // proline metabolic process // traceable author statement /// 0006562 // proline catabolic process // inferred from electronic annotation /// 0006562 // proline catabolic process // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004657 // proline dehydrogenase activity // inferred from direct assay /// 0004657 // proline dehydrogenase activity // inferred from electronic annotation /// 0004657 // proline dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 215683_at AF070628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070628.1 /DEF=Homo sapiens clone 24803 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283895 /UG=Hs.32766 Homo sapiens clone 24803 mRNA sequence AF070628 RBFA downstream neighbor (non-protein coding) RBFADN 100506070 NR_103445 215684_s_at AL096741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096741.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586O0223 (from clone DKFZp586O0223). /FEA=mRNA /DB_XREF=gi:5419897 /UG=Hs.49005 hypothetical protein AL096741 activating signal cointegrator 1 complex subunit 2 ASCC2 84164 NM_001242906 /// NM_032204 /// XM_005261775 /// XM_005261776 /// XM_005261777 /// XM_005261778 /// XM_005261779 /// XM_006724334 /// XM_006724335 /// XM_006724336 /// XM_006724337 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215685_s_at BE792224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE792224 /FEA=EST /DB_XREF=gi:10213422 /DB_XREF=est:601583540F1 /CLONE=IMAGE:3938145 /UG=Hs.419 distal-less homeo box 2 BE792224 distal-less homeobox 2 DLX2 1746 NM_004405 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0021544 // subpallium development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0021882 // regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment // inferred from electronic annotation /// 0021892 // cerebral cortex GABAergic interneuron differentiation // inferred from electronic annotation /// 0021893 // cerebral cortex GABAergic interneuron fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 215686_x_at AL031224 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031224 /DEF=Human DNA sequence from clone 336H9 on chromosome 6p12.1-21.1. Contains the alternatively spliced TFAP2B gene for transcription factor AP-2 beta (activating enhancer-binding protein 2 beta), a novel transcription factor AP-2 LIKE gene and a novel ... /FEA=CDS_3 /DB_XREF=gi:3947808 /UG=Hs.33102 transcription factor AP-2 beta (activating enhancer-binding protein 2 beta) AL031224 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) TFAP2B 7021 NM_003221 /// XM_006715176 /// XM_006715177 /// XM_006715178 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0003091 // renal water homeostasis // inferred from sequence or structural similarity /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007423 // sensory organ development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from expression pattern /// 0010960 // magnesium ion homeostasis // inferred from sequence or structural similarity /// 0030510 // regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0035136 // forelimb morphogenesis // inferred from sequence or structural similarity /// 0035137 // hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045595 // regulation of cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype /// 0055062 // phosphate ion homeostasis // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0055075 // potassium ion homeostasis // inferred from sequence or structural similarity /// 0055078 // sodium ion homeostasis // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from sequence or structural similarity /// 0072044 // collecting duct development // inferred from sequence or structural similarity /// 0072210 // metanephric nephron development // inferred from electronic annotation /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 0097275 // cellular ammonia homeostasis // inferred from sequence or structural similarity /// 0097276 // cellular creatinine homeostasis // inferred from sequence or structural similarity /// 0097277 // cellular urea homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0001158 // enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from direct assay 215687_x_at AA393484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA393484 /FEA=EST /DB_XREF=gi:2046452 /DB_XREF=est:zt71f01.r1 /CLONE=IMAGE:727801 /UG=Hs.41143 phosphoinositide-specific phospholipase C-beta 1 AA393484 phospholipase C, beta 1 (phosphoinositide-specific) PLCB1 23236 NM_015192 /// NM_182734 /// XM_005260681 /// XM_006723555 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007215 // glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007613 // memory // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035722 // interleukin-12-mediated signaling pathway // inferred from direct assay /// 0035723 // interleukin-15-mediated signaling pathway // inferred from direct assay /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048639 // positive regulation of developmental growth // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060466 // activation of meiosis involved in egg activation // inferred from sequence or structural similarity /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0080154 // regulation of fertilization // inferred from sequence or structural similarity /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity /// 2000344 // positive regulation of acrosome reaction // inferred from sequence or structural similarity /// 2000438 // negative regulation of monocyte extravasation // inferred from sequence or structural similarity /// 2000560 // positive regulation of CD24 biosynthetic process // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from sequence or structural similarity /// 0004435 // phosphatidylinositol phospholipase C activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 215688_at AL359931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359931.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 288936. /FEA=mRNA /DB_XREF=gi:8977886 /UG=Hs.48607 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 288936 AL359931 Ras protein-specific guanine nucleotide-releasing factor 1 RASGRF1 5923 NM_001145648 /// NM_002891 /// NM_153815 /// XM_005254578 /// XM_006720627 /// XM_006720628 /// XM_006720629 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007616 // long-term memory // non-traceable author statement /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0046579 // positive regulation of Ras protein signal transduction // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0043005 // neuron projection // non-traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 215689_s_at AI056852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI056852 /FEA=EST /DB_XREF=gi:3330641 /DB_XREF=est:oy98h02.x1 /CLONE=IMAGE:1673907 /UG=Hs.46319 sex hormone-binding globulin AI056852 sex hormone-binding globulin SHBG 6462 NM_001040 /// NM_001146279 /// NM_001146280 /// NM_001146281 /// NM_001289113 /// NM_001289114 /// NM_001289115 /// NM_001289116 /// XM_005256762 /// XM_005256765 /// XM_006721569 0007285 // primary spermatocyte growth // inferred from electronic annotation /// 0009914 // hormone transport // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005497 // androgen binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement 215690_x_at AL157437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157437.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E1512 (from clone DKFZp434E1512); partial cds. /FEA=mRNA /GEN=DKFZp434E1512 /PROD=hypothetical protein /DB_XREF=gi:7018511 /UG=Hs.4742 anchor attachment protein 1 (Gaa1p, yeast) homolog AL157437 glycosylphosphatidylinositol anchor attachment 1 GPAA1 8733 NM_003801 0006461 // protein complex assembly // non-traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042765 // GPI-anchor transamidase complex // traceable author statement 0003923 // GPI-anchor transamidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // non-traceable author statement /// 0034235 // GPI anchor binding // inferred from mutant phenotype 215691_x_at AV702994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702994 /FEA=EST /DB_XREF=gi:10719324 /DB_XREF=est:AV702994 /CLONE=ADBAPB06 /UG=Hs.46967 HSPCO34 protein AV702994 heat shock protein family B (small), member 11 HSPB11 51668 NM_016126 /// XM_005270942 /// XM_005270943 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005929 // cilium // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 215692_s_at BE645386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE645386 /FEA=EST /DB_XREF=gi:9969697 /DB_XREF=est:7e80g06.x1 /CLONE=IMAGE:3288826 /UG=Hs.46638 chromosome 11 open reading frame 8 BE645386 metallophosphoesterase domain containing 2 MPPED2 744 NM_001145399 /// NM_001584 /// XM_005253110 /// XM_005253111 /// XM_005253112 /// XM_005253113 /// XM_005253114 /// XM_006718304 /// XM_006718305 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215693_x_at AL512707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512707.1 /DEF=Homo sapiens mRNA; cDNA DKFZp667N057 (from clone DKFZp667N057). /FEA=mRNA /DB_XREF=gi:12224949 /UG=Hs.65234 hypothetical protein FLJ20596 AL512707 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 DDX27 55661 NM_017895 /// XM_006723815 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215694_at AK022348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022348.1 /DEF=Homo sapiens cDNA FLJ12286 fis, clone MAMMA1001768, weakly similar to CELL DIVISION CYCLE PROTEIN 48 HOMOLOG MJ1156. /FEA=mRNA /DB_XREF=gi:10433725 /UG=Hs.5555 hypothetical protein MGC5347 AK022348 spermatogenesis associated 5-like 1 SPATA5L1 79029 NM_024063 /// NR_027635 /// XM_005254657 /// XR_243126 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 215695_s_at U94357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U94357.1 /DEF=Homo sapiens glycogenin-2 delta (glycogenin-2) mRNA, partial cds. /FEA=mRNA /GEN=glycogenin-2 /PROD=glycogenin-2 delta /DB_XREF=gi:2618756 /UG=Hs.58589 glycogenin 2 U94357 glycogenin 2 GYG2 8908 NM_001079855 /// NM_001184702 /// NM_001184703 /// NM_001184704 /// NM_003918 /// XM_005274617 /// XM_005274618 /// XM_005274619 /// XM_005274621 /// XM_005274622 /// XM_006724521 /// XM_006724522 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 215696_s_at BC001404 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001404.1 /DEF=Homo sapiens, clone IMAGE:3139772, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3139772) /DB_XREF=gi:12655104 /UG=Hs.5716 KIAA0310 gene product BC001404 SEC16 homolog A (S. cerevisiae) SEC16A 9919 NM_001276418 /// NM_014866 /// XM_005266132 /// XM_005266133 /// XM_005266134 /// XM_005266136 /// XM_005266137 0006810 // transport // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0048208 // COPII vesicle coating // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 215697_at AF052172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052172.1 /DEF=Homo sapiens clone 24617 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360483 /UG=Hs.64125 Homo sapiens clone 24617 mRNA sequence AF052172 215698_at AF007135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007135.1 /DEF=Homo sapiens clone 23592 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2852610 /UG=Hs.76272 retinoblastoma-binding protein 2 AF007135 lysine (K)-specific demethylase 5A KDM5A 5927 NM_001042603 /// NM_005056 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 215699_x_at AL096768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096768 /DEF=Human DNA sequence from clone RP5-858B16 on chromosome 22 Contains the KIAA0542 gene and the PISD gene for phosphatidylserine decarboxylase (PSSC, EC 4.1.1.65) . Contains ESTs, GSSs and a putative CpG island /FEA=mRNA_2 /DB_XREF=gi:5596770 /UG=Hs.62209 KIAA0542 gene product AL096768 Sfi1 homolog, spindle assembly associated (yeast) SFI1 9814 NM_001007467 /// NM_001258325 /// NM_001258326 /// NM_001258327 /// NM_014775 /// XM_005261868 /// XM_005261869 /// XM_005261870 /// XM_005261871 /// XM_005261872 /// XM_005261873 /// XM_005261874 /// XM_006724388 /// XM_006724389 /// XM_006724390 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 215700_x_at AL050397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050397.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K1522 (from clone DKFZp564K1522); partial cds. /FEA=mRNA /GEN=DKFZp564K1522 /PROD=hypothetical protein /DB_XREF=gi:4914620 /UG=Hs.6132 copine VI (neuronal) AL050397 copine VI (neuronal) CPNE6 9362 NM_001280558 /// NM_006032 /// XM_005268216 /// XM_005268217 0006629 // lipid metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement 215701_at AL109666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109666.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35907. /FEA=mRNA /DB_XREF=gi:5689800 /UG=Hs.7242 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35907 AL109666 215702_s_at W60595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W60595 /FEA=EST /DB_XREF=gi:1367354 /DB_XREF=est:zc91b04.s1 /CLONE=IMAGE:338479 /UG=Hs.663 cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) W60595 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) CFTR 1080 NM_000492 /// XM_006715842 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0015705 // iodide transport // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // non-traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement /// 1902943 // positive regulation of voltage-gated chloride channel activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031205 // endoplasmic reticulum Sec complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005224 // ATP-binding and phosphorylation-dependent chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from direct assay /// 0005260 // channel-conductance-controlling ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 215703_at W60595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W60595 /FEA=EST /DB_XREF=gi:1367354 /DB_XREF=est:zc91b04.s1 /CLONE=IMAGE:338479 /UG=Hs.663 cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) W60595 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) CFTR 1080 NM_000492 /// XM_006715842 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0015705 // iodide transport // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // non-traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement /// 1902943 // positive regulation of voltage-gated chloride channel activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031205 // endoplasmic reticulum Sec complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005224 // ATP-binding and phosphorylation-dependent chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from direct assay /// 0005260 // channel-conductance-controlling ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 215704_at AL356504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL356504 /DEF=Human DNA sequence from clone RP1-14N1 on chromosome 1q21.1-21.3 Contains ESTs, GSSs and STSs. Contains the FLG gene for profilaggrin and part of a gene for a novel S-100ICaBP type calcium binding domain protein similar to trichohyalin.n /FEA=mRNA /DB_XREF=gi:9588237 /UG=Hs.73995 filaggrin AL356504 filaggrin FLG 2312 NM_002016 0007275 // multicellular organismal development // non-traceable author statement /// 0030216 // keratinocyte differentiation // traceable author statement /// 0061436 // establishment of skin barrier // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215705_at BC000750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000750.1 /DEF=Homo sapiens, clone IMAGE:2961155, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:2961155) /DB_XREF=gi:12653912 /UG=Hs.75180 protein phosphatase 5, catalytic subunit BC000750 protein phosphatase 5, catalytic subunit PPP5C 5536 NM_001204284 /// NM_006247 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043278 // response to morphine // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215706_x_at BC002323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002323.1 /DEF=Homo sapiens, Similar to thyroid hormone receptor interactor 6, clone IMAGE:3504464, mRNA, partial cds. /FEA=mRNA /PROD=Similar to thyroid hormone receptor interactor6 /DB_XREF=gi:12803044 /UG=Hs.75873 zyxin BC002323 zyxin ZYX 7791 NM_001010972 /// NM_003461 /// XM_005250052 /// XM_005250053 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215707_s_at AV725328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV725328 /FEA=EST /DB_XREF=gi:10830606 /DB_XREF=est:AV725328 /CLONE=HTCAVD03 /UG=Hs.74621 prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) AV725328 prion protein PRNP 5621 NM_000311 /// NM_001080121 /// NM_001080122 /// NM_001080123 /// NM_001271561 /// NM_183079 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006878 // cellular copper ion homeostasis // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032703 // negative regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070885 // negative regulation of calcineurin-NFAT signaling cascade // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 215708_s_at AL121975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121975 /DEF=Human DNA sequence from clone RP3-422B11 on chromosome 6p11.2-12.3 Contains ESTs, STSs and GSSs. Contains part of the PRIM2A gene for two isoforms of DNA primase large subunit (polypeptide 2A, p58) /FEA=mRNA_1 /DB_XREF=gi:9663355 /UG=Hs.74519 primase, polypeptide 2A (58kD) AL121975 primase, DNA, polypeptide 2 (58kDa) /// primase, DNA, polypeptide 2 (58kDa) pseudogene PRIM2 /// PRIM2B 5558 /// 100996481 NM_000947 /// NM_001282487 /// NM_001282488 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006269 // DNA replication, synthesis of RNA primer // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 1990077 // primosome complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003896 // DNA primase activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 215709_at AL121975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121975 /DEF=Human DNA sequence from clone RP3-422B11 on chromosome 6p11.2-12.3 Contains ESTs, STSs and GSSs. Contains part of the PRIM2A gene for two isoforms of DNA primase large subunit (polypeptide 2A, p58) /FEA=mRNA_1 /DB_XREF=gi:9663355 /UG=Hs.74519 primase, polypeptide 2A (58kD) AL121975 primase, DNA, polypeptide 2 (58kDa) /// primase, DNA, polypeptide 2 (58kDa) pseudogene PRIM2 /// PRIM2B 5558 /// 100996481 NM_000947 /// NM_001282487 /// NM_001282488 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006269 // DNA replication, synthesis of RNA primer // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 1990077 // primosome complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003896 // DNA primase activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 215710_at AK021929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021929.1 /DEF=Homo sapiens cDNA FLJ11867 fis, clone HEMBA1006976, weakly similar to H.sapiens mRNA for Gal-beta(1-31-4)GlcNAc alpha-2.3-sialyltransferase. /FEA=mRNA /DB_XREF=gi:10433229 /UG=Hs.75268 sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) AK021929 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST3GAL4 6484 NM_001254757 /// NM_001254758 /// NM_001254759 /// NM_006278 /// XM_005271649 /// XM_005271650 /// XM_005271651 /// XM_006718896 /// XM_006718897 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047288 // monosialoganglioside sialyltransferase activity // inferred from electronic annotation 215711_s_at AJ277546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ277546 /DEF=Homo sapiens WEE1 gene for protein kinase and partial ZNF143 gene for zinc finger transcription factor /FEA=CDS_2 /DB_XREF=gi:11140021 /UG=Hs.75188 wee1+ (S. pombe) homolog AJ277546 WEE1 G2 checkpoint kinase WEE1 7465 NM_001143976 /// NM_003390 /// XM_005253118 /// XM_005253119 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215712_s_at AW338791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW338791 /FEA=EST /DB_XREF=gi:6835417 /DB_XREF=est:ha66a11.x1 /CLONE=IMAGE:2878652 /UG=Hs.839 insulin-like growth factor binding protein, acid labile subunit AW338791 insulin-like growth factor binding protein, acid labile subunit IGFALS 3483 NM_001146006 /// NM_004970 /// NR_027389 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // traceable author statement 215713_at AK026778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026778.1 /DEF=Homo sapiens cDNA: FLJ23125 fis, clone LNG08217. /FEA=mRNA /DB_XREF=gi:10439709 /UG=Hs.76325 step II splicing factor SLU7 AK026778 215714_s_at AF254822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF254822 /DEF=Homo sapiens SMARCA4 isoform (SMARCA4) gene, complete cds, alternatively spliced /FEA=CDS_2 /DB_XREF=gi:10946127 /UG=Hs.78202 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 AF254822 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMARCA4 6597 NM_001128844 /// NM_001128845 /// NM_001128846 /// NM_001128847 /// NM_001128848 /// NM_001128849 /// NM_003072 /// XM_005260028 /// XM_005260030 /// XM_005260031 /// XM_005260032 /// XM_005260033 /// XM_005260034 /// XM_005260035 /// XM_006722845 /// XM_006722846 /// XM_006722847 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006200 // ATP catabolic process // inferred from genetic interaction /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007403 // glial cell fate determination // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from genetic interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 215715_at BC000563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000563.1 /DEF=Homo sapiens, clone IMAGE:3162672, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3162672) /DB_XREF=gi:12653576 /UG=Hs.78036 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 BC000563 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 215716_s_at L14561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L14561 /DEF=Homo sapiens plasma membrane calcium ATPase isoform 1 (ATP2B1) gene, alternative splice products, partial cds /FEA=mRNA_2 /DB_XREF=gi:4165324 /UG=Hs.78546 ATPase, Ca++ transporting, plasma membrane 1 L14561 ATPase, Ca++ transporting, plasma membrane 1 ATP2B1 490 NM_001001323 /// NM_001682 /// XM_005268919 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215717_s_at X62009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X62009.1 /DEF=Homo sapiens partial mRNA for fibrillin 5. /FEA=mRNA /PROD=fibrillin 5 /DB_XREF=gi:31399 /UG=Hs.79432 fibrillin 2 (congenital contractural arachnodactyly) X62009 fibrillin 2 FBN2 2201 NM_001999 0009653 // anatomical structure morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0060346 // bone trabecula formation // inferred from sequence or structural similarity 0001527 // microfibril // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215718_s_at AI949220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI949220 /FEA=EST /DB_XREF=gi:5741530 /DB_XREF=est:wq20e12.x1 /CLONE=IMAGE:2471854 /UG=Hs.78893 KIAA0244 protein AI949220 PHD finger protein 3 PHF3 23469 NM_001290259 /// NM_001290260 /// NM_015153 /// XM_005248701 /// XM_005248702 /// XM_005248703 /// XM_006715426 /// XM_006715427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215719_x_at X83493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83493.1 /DEF=H.sapiens mRNA for FasApo-1 (clone pCRTM11-FasdeltaTM). /FEA=mRNA /DB_XREF=gi:971457 /UG=Hs.82359 tumor necrosis factor receptor superfamily, member 6 X83493 Fas cell surface death receptor FAS 355 NM_000043 /// NM_152871 /// NM_152872 /// NM_152873 /// NM_152874 /// NM_152875 /// NM_152876 /// NM_152877 /// NR_028033 /// NR_028034 /// NR_028035 /// NR_028036 /// XM_006717819 0002377 // immunoglobulin production // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006927 // transformed cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0019724 // B cell mediated immunity // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 215720_s_at AL031778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031778 /DEF=Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine... /FEA=mRNA_6 /DB_XREF=gi:4153958 /UG=Hs.797 nuclear transcription factor Y, alpha AL031778 nuclear transcription factor Y, alpha NFYA 4800 NM_002505 /// NM_021705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215721_at X58397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X58397.1 /DEF=Human CLL-12 transcript of unrearranged immunoglobulin V(H)5 gene. /FEA=mRNA /GEN=immunoglobulin heavy chain /DB_XREF=gi:33615 /UG=Hs.81220 Human CB-4 transcript of unrearranged immunoglobulin V(H)5 gene X58397 immunoglobulin heavy constant gamma 1 (G1m marker) /// uncharacterized LOC100293211 IGHG1 /// LOC100293211 3500 /// 100293211 XM_006710246 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215722_s_at AJ130971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ130971.1 /DEF=Homo sapiens mRNA for U2 snRNP-specific A protein, alternative transcript 4. /FEA=mRNA /PROD=U2 snRNP-specific A protein /DB_XREF=gi:3970726 /UG=Hs.80506 small nuclear ribonucleoprotein polypeptide A AJ130971 small nuclear ribonucleoprotein polypeptide A' SNRPA1 6627 NM_003090 /// XR_243213 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005686 // U2 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215723_s_at AJ276230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276230.1 /DEF=Homo sapiens mRNA for partial phospholipase D1, splice variant PLD1ab2. /FEA=mRNA /GEN=PLD1 /PROD=phospholipase D1 /DB_XREF=gi:7161182 /UG=Hs.82587 phospholipase D1, phophatidylcholine-specific AJ276230 phospholipase D1, phosphatidylcholine-specific PLD1 5337 NM_001130081 /// NM_002662 /// XM_005247533 /// XM_005247534 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 215724_at AJ276230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276230.1 /DEF=Homo sapiens mRNA for partial phospholipase D1, splice variant PLD1ab2. /FEA=mRNA /GEN=PLD1 /PROD=phospholipase D1 /DB_XREF=gi:7161182 /UG=Hs.82587 phospholipase D1, phophatidylcholine-specific AJ276230 phospholipase D1, phosphatidylcholine-specific PLD1 5337 NM_001130081 /// NM_002662 /// XM_005247533 /// XM_005247534 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 215725_at L77561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L77561.1 /DEF=Homo sapiens DGS-D mRNA, 3 end. /FEA=mRNA /DB_XREF=gi:1377759 /UG=Hs.83775 DiGeorge syndrome gene D L77561 DiGeorge syndrome critical region gene 11 (non-protein coding) DGCR11 25786 NR_024157 215726_s_at M22976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M22976.1 /DEF=Human cytochrome b5 mRNA, 3 end. /FEA=mRNA /GEN=CYB5 /PROD=cytochrome b5 /DB_XREF=gi:181228 /UG=Hs.83834 cytochrome b-5 M22976 cytochrome b5 type A (microsomal) CYB5A 1528 NM_001190807 /// NM_001914 /// NM_148923 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215727_x_at AF064839 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF064839.1 /DEF=Homo sapiens map 3p21; 3.15 cR from WI-9324 repeat region, complete sequence. /FEA=mRNA /DB_XREF=gi:4206051 /UG=Hs.83530 hypothetical protein AF064839 armadillo repeat containing, X-linked 6 ARMCX6 54470 NM_001009584 /// NM_001184768 /// NM_019007 /// NR_033669 /// NR_033670 /// XM_006724665 0016021 // integral component of membrane // inferred from electronic annotation 215728_s_at AL031848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031848 /DEF=Human DNA sequence from clone 202O8 on chromosome 1p36.11-36.31. Contains the 5 part of a gene for a novel rat Espin LIKE protein containing Ank repeats, the gene for the ortholog of rodent HES2 (Hairy and Enhacer of Split 2) and the 5 end of th... /FEA=CDS_4 /DB_XREF=gi:4914512 /UG=Hs.8679 cytosolic acyl coenzyme A thioester hydrolase AL031848 acyl-CoA thioesterase 7 ACOT7 11332 NM_007274 /// NM_181862 /// NM_181863 /// NM_181864 /// NM_181865 /// NM_181866 /// XM_005263427 0006629 // lipid metabolic process // traceable author statement /// 0009062 // fatty acid catabolic process // inferred from electronic annotation /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0036114 // medium-chain fatty-acyl-CoA catabolic process // inferred from direct assay /// 0036116 // long-chain fatty-acyl-CoA catabolic process // inferred from direct assay /// 0051792 // medium-chain fatty acid biosynthetic process // inferred from direct assay /// 1900535 // palmitic acid biosynthetic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0047617 // acyl-CoA hydrolase activity // inferred from electronic annotation 215729_s_at BE542323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE542323 /FEA=EST /DB_XREF=gi:9770968 /DB_XREF=est:601067066F1 /CLONE=IMAGE:3453257 /UG=Hs.9030 TONDU BE542323 vestigial-like family member 1 VGLL1 51442 NM_016267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003713 // transcription coactivator activity // traceable author statement 215730_at BE542323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE542323 /FEA=EST /DB_XREF=gi:9770968 /DB_XREF=est:601067066F1 /CLONE=IMAGE:3453257 /UG=Hs.9030 TONDU BE542323 vestigial-like family member 1 VGLL1 51442 NM_016267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003713 // transcription coactivator activity // traceable author statement 215731_s_at X98258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X98258.1 /DEF=H.sapiens mRNA for M-phase phosphoprotein, mpp9. /FEA=mRNA /GEN=mpp9 /PROD=M-phase phosphoprotein 9 /DB_XREF=gi:1770467 /UG=Hs.86178 M-phase phosphoprotein 9 X98258 M-phase phosphoprotein 9 MPHOSPH9 10198 NM_022782 /// NR_103517 /// XM_006719187 /// XM_006719188 /// XM_006719189 /// XM_006719190 /// XM_006719191 /// XM_006719192 /// XR_429068 /// XR_429069 /// XR_429070 0000087 // mitotic M phase // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 215732_s_at AK023924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023924.1 /DEF=Homo sapiens cDNA FLJ13862 fis, clone THYRO1001120, moderately similar to Homo sapiens deltex (Dx) mRNA. /FEA=mRNA /DB_XREF=gi:10436011 /UG=Hs.89135 KIAA1528 protein AK023924 deltex 2, E3 ubiquitin ligase /// probable E3 ubiquitin-protein ligase DTX2-like DTX2 /// LOC102725292 113878 /// 102725292 NM_001102594 /// NM_001102595 /// NM_001102596 /// NM_020892 /// XM_005250131 /// XM_005250132 /// XM_005250134 /// XM_005250135 /// XM_006710184 /// XM_006715846 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215733_x_at AJ012833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ012833.1 /DEF=Homo sapiens mRNA for CTL-recognized antigen on melanoma (CAMEL). /FEA=mRNA /GEN=CAMEL /PROD=CTL-recognized antigen on melanoma (CAMEL) /DB_XREF=gi:3893216 /UG=Hs.87225 cancertestis antigen 2 AJ012833 cancer/testis antigen 2 CTAG2 30848 NM_020994 /// NM_172377 0005813 // centrosome // inferred from direct assay 215734_at AW182303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW182303 /FEA=EST /DB_XREF=gi:6450763 /DB_XREF=est:xj41a06.x1 /CLONE=IMAGE:2659762 /UG=Hs.90010 Homo sapiens chromosome 19, cosmid R26660 AW182303 IZUMO family member 4 IZUMO4 113177 NM_001031735 /// NM_001039846 /// NM_052878 /// XM_005259480 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 215735_s_at AC005600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005600 /DEF=Homo sapiens chromosome 16, P1 clone 109-9G (LANL), complete sequence /FEA=CDS_1 /DB_XREF=gi:3522919 /UG=Hs.90303 tuberous sclerosis 2 AC005600 tuberous sclerosis 2 TSC2 7249 NM_000548 /// NM_001077183 /// NM_001114382 /// NM_021055 /// NM_021056 /// XM_005255527 /// XM_005255528 /// XM_005255529 /// XM_005255530 /// XM_005255531 /// XM_005255532 0001666 // response to hypoxia // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from sequence or structural similarity /// 0006897 // endocytosis // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // not recorded /// 0032007 // negative regulation of TOR signaling // not recorded /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0046626 // regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // not recorded /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // not recorded /// 0051898 // negative regulation of protein kinase B signaling // not recorded /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0033596 // TSC1-TSC2 complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005096 // GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 215736_at AF035317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035317.1 /DEF=Homo sapiens clone 23892 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2661080 /UG=Hs.91916 Homo sapiens clone 23892 mRNA sequence AF035317 potassium channel, subfamily V, member 1 KCNV1 27012 NM_014379 /// XM_005250866 /// XM_005250867 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0015459 // potassium channel regulator activity // traceable author statement 215737_x_at X90824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X90824.1 /DEF=H.sapiens mRNA for USF2a & USF2b, clone P9DH. /FEA=mRNA /GEN=USF2 /PROD=USF2a, USF2b protein /DB_XREF=gi:1279506 /UG=Hs.93649 upstream transcription factor 2, c-fos interacting X90824 upstream transcription factor 2, c-fos interacting USF2 7392 NM_003367 /// NM_207291 /// XM_005259197 0000430 // regulation of transcription from RNA polymerase II promoter by glucose // inferred by curator /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from mutant phenotype /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007595 // lactation // inferred from electronic annotation /// 0019086 // late viral transcription // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 215738_at U79295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79295.1 /DEF=Human clone 23961 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1710277 /UG=Hs.90866 Human clone 23961 mRNA sequence U79295 long intergenic non-protein coding RNA 563 LINC00563 100861554 NR_047493 215739_s_at AJ003062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ003062.1 /DEF=Homo sapiens mRNA for protein encoded by Saccharomyces cerevisiae SPC98 homologue. /FEA=mRNA /DB_XREF=gi:3152381 /UG=Hs.9884 spindle pole body protein AJ003062 tubulin, gamma complex associated protein 3 TUBGCP3 10426 NM_001286277 /// NM_001286278 /// NM_001286279 /// NM_006322 /// XM_005268293 /// XR_245841 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007338 // single fertilization // non-traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // non-traceable author statement /// 0005827 // polar microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from direct assay 215740_at AU148808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148808 /FEA=EST /DB_XREF=gi:11010329 /DB_XREF=est:AU148808 /CLONE=NT2RM4000979 /UG=Hs.96927 Homo sapiens cDNA FLJ12573 fis, clone NT2RM4000979 AU148808 uncharacterized LOC100130741 LOC100130741 100130741 XM_001720612 /// XM_001721890 215741_x_at AB015332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB015332.1 /DEF=Homo sapiens HRIHFB2018 mRNA, partial cds. /FEA=mRNA /GEN=HRIHFB2018 /DB_XREF=gi:3970853 /UG=Hs.96200 neighbor of A-kinase anchoring protein 95 AB015332 A kinase (PRKA) anchor protein 8-like AKAP8L 26993 NM_001291478 /// NM_014371 /// NR_111971 /// XM_005259854 /// XR_244065 /// XR_244066 /// XR_430135 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0017151 // DEAD/H-box RNA helicase binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215742_at AK022219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022219.1 /DEF=Homo sapiens cDNA FLJ12157 fis, clone MAMMA1000500. /FEA=mRNA /DB_XREF=gi:10433569 /UG=Hs.98812 Homo sapiens cDNA FLJ12157 fis, clone MAMMA1000500 AK022219 215743_at AL134489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL134489 /FEA=EST /DB_XREF=gi:6602676 /DB_XREF=est:DKFZp547L045_r1 /CLONE=DKFZp547L045 /UG=Hs.94986 ribonuclease P (38kD) AL134489 N-myristoyltransferase 2 NMT2 9397 NM_004808 /// XM_005252642 /// XM_005252643 /// XM_006717539 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 215744_at AW514140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514140 /FEA=EST /DB_XREF=gi:7152222 /DB_XREF=est:xt82h10.x1 /CLONE=IMAGE:2792995 /UG=Hs.99969 fusion, derived from t(12;16) malignant liposarcoma AW514140 FUS RNA binding protein FUS 2521 NM_001010850 /// NM_001170634 /// NM_001170937 /// NM_004960 /// NR_028388 /// XM_005255233 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215745_at L34409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L34409.1 /DEF=Homo Sapiens (clone B3B3E13) chromosome 4p16.3 DNA fragment. /FEA=mRNA /DB_XREF=gi:600517 /UG=Hs.94799 Homo Sapiens (clone B3B3E13) chromosome 4p16.3 DNA fragment L34409 215746_at L34409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L34409.1 /DEF=Homo Sapiens (clone B3B3E13) chromosome 4p16.3 DNA fragment. /FEA=mRNA /DB_XREF=gi:600517 /UG=Hs.94799 Homo Sapiens (clone B3B3E13) chromosome 4p16.3 DNA fragment L34409 215747_s_at X06130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06130.1 /DEF=Human mRNA for cell cycle gene RCC1. /FEA=mRNA /DB_XREF=gi:35906 /UG=Hs.84746 chromosome condensation 1 X06130 regulator of chromosome condensation 1 RCC1 1104 NM_001048194 /// NM_001048195 /// NM_001048199 /// NM_001269 /// NR_030725 /// NR_030726 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032316 // regulation of Ran GTPase activity // inferred from direct assay /// 0032316 // regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from direct assay /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay 215748_at AL050370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050370.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566C0546 (from clone DKFZp566C0546). /FEA=mRNA /DB_XREF=gi:4914605 /UG=Hs.59728 Homo sapiens mRNA; cDNA DKFZp566C0546 (from clone DKFZp566C0546) AL050370 kelch-like family member 35 KLHL35 283212 NM_001039548 /// NM_173583 215749_s_at AK001574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001574.1 /DEF=Homo sapiens cDNA FLJ10712 fis, clone NT2RP3000919, highly similar to Rattus norvegicus golgi peripheral membrane protein p65 mRNA. /FEA=mRNA /DB_XREF=gi:7022910 /UG=Hs.4291 hypothetical protein FLJ23443 AK001574 golgi reassembly stacking protein 1, 65kDa GORASP1 64689 NM_001278789 /// NM_001278790 /// NM_031899 /// NR_103866 /// NR_103867 /// XM_006713300 /// XM_006713301 /// XM_006713302 /// XR_427284 /// XR_427285 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0050774 // negative regulation of dendrite morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215750_at AB051446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051446.1 /DEF=Homo sapiens mRNA for KIAA1659 protein, partial cds. /FEA=mRNA /GEN=KIAA1659 /PROD=KIAA1659 protein /DB_XREF=gi:13359190 /UG=Hs.326758 Homo sapiens mRNA for KIAA1659 protein, partial cds AB051446 215751_at AK021576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021576.1 /DEF=Homo sapiens cDNA FLJ11514 fis, clone HEMBA1002229. /FEA=mRNA /DB_XREF=gi:10432783 /UG=Hs.306602 Homo sapiens cDNA FLJ11514 fis, clone HEMBA1002229 AK021576 RNA binding motif protein 26 RBM26 64062 NM_001286631 /// NM_001286632 /// NM_018605 /// NM_022118 /// XM_005266491 /// XM_005266492 /// XM_005266493 /// XM_005266494 /// XM_005266496 /// XM_005266497 /// XM_005266498 /// XM_005266499 /// XM_005266501 /// XM_006719855 /// XM_006719856 /// XM_006719857 /// XM_006719858 /// XM_006719859 /// XM_006719860 0006397 // mRNA processing // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215752_at AK026682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026682.1 /DEF=Homo sapiens cDNA: FLJ23029 fis, clone LNG01883. /FEA=mRNA /DB_XREF=gi:10439589 /UG=Hs.306864 Homo sapiens cDNA: FLJ23029 fis, clone LNG01883 AK026682 salt-inducible kinase 2 SIK2 23235 NM_015191 0006468 // protein phosphorylation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046626 // regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215753_at AK021614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021614.1 /DEF=Homo sapiens cDNA FLJ11552 fis, clone HEMBA1003021. /FEA=mRNA /DB_XREF=gi:10432830 /UG=Hs.306606 Homo sapiens cDNA FLJ11552 fis, clone HEMBA1003021 AK021614 215754_at AU148040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148040 /FEA=EST /DB_XREF=gi:11009561 /DB_XREF=est:AU148040 /CLONE=MAMMA1002428 /UG=Hs.301615 Homo sapiens cDNA FLJ12370 fis, clone MAMMA1002428, weakly similar to LYSOSOME MEMBRANE PROTEIN II AU148040 scavenger receptor class B, member 2 SCARB2 950 NM_001204255 /// NM_005506 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 215755_at AK022006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022006.1 /DEF=Homo sapiens cDNA FLJ11944 fis, clone HEMBB1000684. /FEA=mRNA /DB_XREF=gi:10433318 /UG=Hs.300771 Homo sapiens cDNA FLJ11944 fis, clone HEMBB1000684 AK022006 RNA, 7SK small nuclear pseudogene 150 RN7SKP150 215756_at AU153979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153979 /FEA=EST /DB_XREF=gi:11015500 /DB_XREF=est:AU153979 /CLONE=NT2RP3004470 /UG=Hs.293928 Homo sapiens cDNA FLJ14231 fis, clone NT2RP3004470 AU153979 long intergenic non-protein coding RNA 1136 LINC01136 730227 NR_034150 /// NR_034151 215757_at AK022387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022387.1 /DEF=Homo sapiens cDNA FLJ12325 fis, clone MAMMA1002125. /FEA=mRNA /DB_XREF=gi:10433772 /UG=Hs.287514 Homo sapiens cDNA FLJ12325 fis, clone MAMMA1002125 AK022387 protein kinase, DNA-activated, catalytic polypeptide PRKDC 5591 NM_001081640 /// NM_006904 0000723 // telomere maintenance // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002328 // pro-B cell differentiation // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0072431 // signal transduction involved in mitotic G1 DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005958 // DNA-dependent protein kinase-DNA ligase 4 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215758_x_at AC007204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007204 /DEF=Homo sapiens chromosome 19, BAC 273239 (CIT-B-320G13) /FEA=CDS /DB_XREF=gi:4559317 /UG=Hs.284229 Homo sapiens chromosome 19, BAC 273239 (CIT-B-320G13) AC007204 zinc finger protein 93 ZNF93 81931 NM_001004126 /// NM_031218 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 215759_at AK022118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022118.1 /DEF=Homo sapiens cDNA FLJ12056 fis, clone HEMBB1002050. /FEA=mRNA /DB_XREF=gi:10433441 /UG=Hs.276475 hypothetical protein FLJ12056 AK022118 ankyrin repeat domain 53 ANKRD53 79998 NM_001115116 /// NM_024933 /// XM_005264569 215760_s_at AC005390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005390 /DEF=Homo sapiens chromosome 19, cosmid R31180 /FEA=CDS_1 /DB_XREF=gi:3399675 /UG=Hs.251410 Homo sapiens chromosome 19, cosmid R31180 AC005390 strawberry notch homolog 2 (Drosophila) SBNO2 22904 NM_001100122 /// NM_014963 /// XM_005259519 /// XM_005259520 0002281 // macrophage activation involved in immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype 215761_at AK000156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000156.1 /DEF=Homo sapiens cDNA FLJ20149 fis, clone COL08213. /FEA=mRNA /DB_XREF=gi:7020059 /UG=Hs.272193 Homo sapiens cDNA FLJ20149 fis, clone COL08213 AK000156 Dmx-like 2 DMXL2 23312 NM_001174116 /// NM_001174117 /// NM_015263 /// XM_005254255 /// XM_005254256 /// XM_005254257 /// XM_005254258 /// XM_006720446 /// XR_243084 /// XR_243085 0005615 // extracellular space // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0017137 // Rab GTPase binding // inferred from direct assay 215762_at BE669609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE669609 /FEA=EST /DB_XREF=gi:10030150 /DB_XREF=est:7e15h11.x1 /CLONE=IMAGE:3282597 /UG=Hs.251411 Homo sapiens mRNA; cDNA DKFZp566B233 (from clone DKFZp566B233) BE669609 215763_at AL080072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080072.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M0616 (from clone DKFZp564M0616). /FEA=mRNA /DB_XREF=gi:5262482 /UG=Hs.21195 Homo sapiens mRNA; cDNA DKFZp564M0616 (from clone DKFZp564M0616) AL080072 215764_x_at AA877641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA877641 /FEA=EST /DB_XREF=gi:2986606 /DB_XREF=est:nr02c04.s1 /CLONE=IMAGE:1160646 /UG=Hs.19121 adaptor-related protein complex 2, alpha 2 subunit AA877641 adaptor-related protein complex 2, alpha 2 subunit AP2A2 161 NM_001242837 /// NM_012305 /// XM_006718159 /// XM_006718160 /// XR_242779 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // non-traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 215765_at AK024051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024051.1 /DEF=Homo sapiens cDNA FLJ13989 fis, clone Y79AA1002083, highly similar to H.sapiens mRNA for MUF1 protein. /FEA=mRNA /DB_XREF=gi:10436322 /UG=Hs.172210 MUF1 protein AK024051 leucine rich repeat containing 41 LRRC41 10489 NM_006369 /// XM_005270376 0016567 // protein ubiquitination // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 215766_at AL096729 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096729.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D044 (from clone DKFZp434D044). /FEA=mRNA /DB_XREF=gi:5419863 /UG=Hs.146581 Homo sapiens mRNA; cDNA DKFZp434D044 (from clone DKFZp434D044) AL096729 glutathione S-transferase alpha 1 GSTA1 2938 NM_145740 /// XM_005249034 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred by curator /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004364 // glutathione transferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 215767_at AF052145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052145.1 /DEF=Homo sapiens clone 24400 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360454 /UG=Hs.159528 Homo sapiens clone 24400 mRNA sequence AF052145 zinc finger protein 804A ZNF804A 91752 NM_194250 0046872 // metal ion binding // inferred from electronic annotation 215768_at AL049337 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049337.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P016 (from clone DKFZp564P016). /FEA=mRNA /DB_XREF=gi:4500118 /UG=Hs.132571 Homo sapiens mRNA; cDNA DKFZp564P016 (from clone DKFZp564P016) AL049337 215769_at AW873544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW873544 /FEA=EST /DB_XREF=gi:8007597 /DB_XREF=est:ho62a01.x1 /CLONE=IMAGE:3041928 /UG=Hs.272500 Human mRNA for T cell receptor, clone IGRA17 AW873544 Homo sapiens TRA mRNA for T cell receptor alpha chain, partial cds, allele:TRAV19*01+TRAJ53*01. /// T cell receptor alpha variable 16 /// /// YME1-like 1 ATPase TRA /// TRAV16 /// TRAV16 /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 215770_at AF065857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF065857 /DEF=Homo sapiens OR7F2P pseudogene, partial sequence /FEA=CDS /DB_XREF=gi:3831594 /UG=Hs.248185 olfactory receptor, family 7, subfamily E, member 2 pseudogene AF065857 olfactory receptor, family 7, subfamily E, member 2 pseudogene OR7E2P 8587 NR_045004 215771_x_at X15786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X15786.1 /DEF=Human ret-II gene. /FEA=mRNA /GEN=retII /DB_XREF=gi:36008 /UG=Hs.241572 golgi autoantigen, golgin subfamily a, 5 X15786 ret proto-oncogene RET 5979 NM_000323 /// NM_020629 /// NM_020630 /// NM_020975 /// XM_006717936 0000165 // MAPK cascade // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007018 // microtubule-based movement // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0035617 // stress granule disassembly // inferred from electronic annotation /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005871 // kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0031985 // Golgi cisterna // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 215772_x_at AL050226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050226.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586M2023 (from clone DKFZp586M2023); partial cds. /FEA=mRNA /GEN=DKFZp586M2023 /PROD=hypothetical protein /DB_XREF=gi:4884469 /UG=Hs.247309 succinate-CoA ligase, GDP-forming, beta subunit AL050226 succinate-CoA ligase, GDP-forming, beta subunit SUCLG2 8801 NM_001177599 /// NM_003848 /// XM_005264773 /// XR_245062 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // non-traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045244 // succinate-CoA ligase complex (GDP-forming) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004776 // succinate-CoA ligase (GDP-forming) activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215773_x_at AJ236912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ236912.1 /DEF=Homo sapiens mRNA for poly-(ADP-ribose) polymerase II. /FEA=mRNA /GEN=PARP2 /PROD=poly-(ADP-ribose) polymerase II /DB_XREF=gi:6688129 /UG=Hs.24284 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 AJ236912 poly (ADP-ribose) polymerase 2 PARP2 10038 NM_001042618 /// NM_005484 /// XM_005267247 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 215774_s_at AV650470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV650470 /FEA=EST /DB_XREF=gi:9871484 /DB_XREF=est:AV650470 /CLONE=GLCCFB08 /UG=Hs.247309 succinate-CoA ligase, GDP-forming, beta subunit AV650470 215775_at BF084105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF084105 /FEA=EST /DB_XREF=gi:10877935 /DB_XREF=est:QV4-CT0491-140900-398-e06 /UG=Hs.247954 Human thrombospondin-1 gene, partial cds BF084105 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 215776_at J05046 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J05046.1 /DEF=Human insulin receptor-related receptor (IRR) mRNA, 3 end. /FEA=mRNA /GEN=INSRR /PROD=insulin receptor-related receptor /DB_XREF=gi:186554 /UG=Hs.248138 insulin receptor-related receptor J05046 insulin receptor-related receptor INSRR 3645 NM_014215 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0030238 // male sex determination // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0071469 // cellular response to alkalinity // inferred from direct assay 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation 215777_at AW405975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW405975 /FEA=EST /DB_XREF=gi:6925032 /DB_XREF=est:UI-HF-BL0-acv-a-05-0-UI.r1 /CLONE=IMAGE:3060368 /UG=Hs.247721 Homo sapiens clone mcg53-54 immunoglobulin lambda light chain variable region 4a mRNA, partial cds AW405975 immunoglobulin lambda variable 4-60 /// IGLV4-60 /// IGLV4-60 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement 0005515 // protein binding // inferred from electronic annotation 215778_x_at AJ006206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ006206 /DEF=Homo sapiens MUC-B1 gene, partial, 5end /FEA=CDS /DB_XREF=gi:4887551 /UG=Hs.247857 Homo sapiens MUC-B1 gene, partial, 5end AJ006206 B1 for mucin HAB1 55547 215779_s_at BE271470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE271470 /FEA=EST /DB_XREF=gi:9145273 /DB_XREF=est:601140646F1 /CLONE=IMAGE:3049883 /UG=Hs.247817 H2B histone family, member A BE271470 histone cluster 1, H2bg /// histone cluster 1, H2bj HIST1H2BG /// HIST1H2BJ 8339 /// 8970 NM_003518 /// NM_021058 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 215780_s_at Z95126 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z95126 /DEF=Human DNA sequence from PAC 30P20 on chromosome Xq21.1-Xq21.3. Contains set pseudogene, ESTs and STS /FEA=CDS /DB_XREF=gi:2342581 /UG=Hs.248054 Human DNA sequence from PAC 30P20 on chromosome Xq21.1-Xq21.3. Contains set pseudogene, ESTs and STS Z95126 SET nuclear proto-oncogene /// SET pseudogene 4 /// SET-like protein SET /// SETP4 /// SETSIP 6418 /// 642869 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 215781_s_at D87012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87012 /DEF=Homo sapiens immunoglobulin lambda gene locus DNA, clone:61D6 /FEA=CDS /DB_XREF=gi:2114263 /UG=Hs.248010 Homo sapiens immunoglobulin lambda gene locus DNA, clone:61D6 D87012 topoisomerase (DNA) III beta TOP3B 8940 NM_001282112 /// NM_001282113 /// NM_003935 /// XM_005261811 /// XM_005261813 /// XM_005261814 /// XM_006724349 /// XM_006724350 /// XM_006724351 /// XM_006724352 /// XR_244395 /// XR_244396 0006265 // DNA topological change // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003916 // DNA topoisomerase activity // traceable author statement /// 0003917 // DNA topoisomerase type I activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215782_at Z95624 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z95624 /DEF=Human DNA sequence from cosmid U237H1 contains Ras like GTPase and ESTs /FEA=CDS /DB_XREF=gi:2117165 /UG=Hs.248013 Human DNA sequence from cosmid U237H1 contains Ras like GTPase and ESTs Z95624 RAB40A, member RAS oncogene family-like RAB40AL 282808 NM_001031834 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 215783_s_at X14174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14174.1 /DEF=Human mRNA for liver-type alkaline phosphatase (EC 3.1.3.1). /FEA=mRNA /DB_XREF=gi:28737 /UG=Hs.250769 alkaline phosphatase, liverbonekidney X14174 alkaline phosphatase, liver/bone/kidney ALPL 249 NM_000478 /// NM_001127501 /// NM_001177520 /// XM_005245818 /// XM_005245820 /// XM_006710546 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0003006 // developmental process involved in reproduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from expression pattern /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071529 // cementum mineralization // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0065010 // extracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016462 // pyrophosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215784_at AA309511 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA309511 /FEA=EST /DB_XREF=gi:1961913 /DB_XREF=est:EST180452 /UG=Hs.249217 CD1E antigen, e polypeptide AA309511 CD1e molecule CD1E 913 NM_001042583 /// NM_001042584 /// NM_001042585 /// NM_001042586 /// NM_001042587 /// NM_001185107 /// NM_001185108 /// NM_001185110 /// NM_001185112 /// NM_001185113 /// NM_001185114 /// NM_001185115 /// NM_030893 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030881 // beta-2-microglobulin binding // not recorded /// 0030883 // endogenous lipid antigen binding // not recorded /// 0030884 // exogenous lipid antigen binding // not recorded /// 0071723 // lipopeptide binding // not recorded 215785_s_at AL161999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161999.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761H087 (from clone DKFZp761H087); partial cds. /FEA=mRNA /GEN=DKFZp761H087 /PROD=hypothetical protein /DB_XREF=gi:7328000 /UG=Hs.258503 p53 inducible protein AL161999 cytoplasmic FMR1 interacting protein 2 CYFIP2 26999 NM_001037332 /// NM_001037333 /// NM_001291721 /// NM_001291722 /// NM_014376 0006915 // apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215786_at AK022170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022170.1 /DEF=Homo sapiens cDNA FLJ12108 fis, clone MAMMA1000009. /FEA=mRNA /DB_XREF=gi:10433505 /UG=Hs.250813 Homo sapiens cDNA FLJ12108 fis, clone MAMMA1000009 AK022170 215787_at AK025094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025094.1 /DEF=Homo sapiens cDNA: FLJ21441 fis, clone COL04422. /FEA=mRNA /DB_XREF=gi:10437541 /UG=Hs.269926 Homo sapiens cDNA: FLJ21441 fis, clone COL04422 AK025094 actin, alpha 2, smooth muscle, aorta ACTA2 59 NM_001141945 /// NM_001613 0006936 // muscle contraction // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0072144 // glomerular mesangial cell development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 215788_at AL137547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137547.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B1120 (from clone DKFZp434B1120). /FEA=mRNA /DB_XREF=gi:6808230 /UG=Hs.259619 Homo sapiens mRNA; cDNA DKFZp434B1120 (from clone DKFZp434B1120) AL137547 KIAA1751 KIAA1751 85452 NM_001003808 /// NM_001080484 /// XM_003119800 /// XM_005244811 /// XM_006710997 /// XM_006710998 215789_s_at AA835004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA835004 /FEA=EST /DB_XREF=gi:2908732 /DB_XREF=est:aj39d06.s1 /CLONE=IMAGE:1392683 /UG=Hs.25924 hypothetical protein AA835004 adherens junctions associated protein 1 AJAP1 55966 NM_001042478 /// NM_018836 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 215790_at AA835004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA835004 /FEA=EST /DB_XREF=gi:2908732 /DB_XREF=est:aj39d06.s1 /CLONE=IMAGE:1392683 /UG=Hs.25924 hypothetical protein AA835004 adherens junctions associated protein 1 AJAP1 55966 NM_001042478 /// NM_018836 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 215791_at AF003738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF003738.1 /DEF=Homo sapiens chromosome 21q22.1 anonymous mRNA sequence. /FEA=mRNA /DB_XREF=gi:2197087 /UG=Hs.268526 Homo sapiens chromosome 21q22.1 anonymous mRNA sequence AF003738 215792_s_at AL109978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109978.1 /DEF=Novel human gene mapping to chomosome 1. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:5764009 /UG=Hs.261134 hypothetical protein FLJ10737 AL109978 DnaJ (Hsp40) homolog, subfamily C, member 11 DNAJC11 55735 NM_018198 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215793_at AF073482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF073482.1 /DEF=Homo sapiens myotubularin related protein 7 mRNA, partial cds. /FEA=mRNA /PROD=myotubularin related protein 7 /DB_XREF=gi:3882997 /UG=Hs.26952 myotubularin related protein 7 AF073482 myotubularin related protein 7 MTMR7 9108 NM_004686 /// XM_006716414 0006470 // protein dephosphorylation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 215794_x_at AC006144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006144 /DEF=Homo sapiens PAC clone RP1-296G17 from Xq23 /FEA=CDS /DB_XREF=gi:4156203 /UG=Hs.272497 Glutamate dehydrogenase-2 AC006144 glutamate dehydrogenase 2 GLUD2 2747 NM_012084 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay 215795_at AK000947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000947.1 /DEF=Homo sapiens cDNA FLJ10085 fis, clone HEMBA1002161, moderately similar to MYOSIN HEAVY CHAIN, CARDIAC MUSCLE BETA ISOFORM. /FEA=mRNA /DB_XREF=gi:7021930 /UG=Hs.272207 myosin, heavy polypeptide 4, skeletal muscle AK000947 myosin, heavy chain 7B, cardiac muscle, beta MYH7B 57644 NM_020884 /// XM_006723839 /// XM_006723840 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 215796_at BF976764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF976764 /FEA=EST /DB_XREF=gi:12343979 /DB_XREF=est:602245805F1 /CLONE=IMAGE:4336969 /UG=Hs.272471 Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence BF976764 Homo sapiens mRNA for T cell receptor alpha variable 13, partial cds, clone: SEB 7. /// T cell receptor alpha variable 13-2 /// AV8S2 /// TRAV13-2 /// TRAV13-2 0005515 // protein binding // inferred from electronic annotation 215797_at AE000659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AE000659 /DEF=Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence /FEA=CDS_2 /DB_XREF=gi:2358025 /UG=Hs.272470 Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence AE000659 T cell receptor alpha variable 8-3 TRAV8-3 28683 215798_at AL133015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133015.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O2417 (from clone DKFZp434O2417); partial cds. /FEA=mRNA /GEN=DKFZp434O2417 /PROD=hypothetical protein /DB_XREF=gi:6453493 /UG=Hs.272307 Homo sapiens mRNA; cDNA DKFZp434O2417 (from clone DKFZp434O2417); partial cds AL133015 aldehyde dehydrogenase 1 family, member L1 ALDH1L1 10840 NM_001270364 /// NM_001270365 /// NM_012190 /// NR_072979 /// XM_006713481 /// XM_006713482 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009258 // 10-formyltetrahydrofolate catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016155 // formyltetrahydrofolate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation 215799_at AK024971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024971.1 /DEF=Homo sapiens cDNA: FLJ21318 fis, clone COL02295. /FEA=mRNA /DB_XREF=gi:10437398 /UG=Hs.97858 SH3-domain binding protein 1 AK024971 uncharacterized LOC101927051 LOC101927051 101927051 NR_109952 215800_at AL137592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137592.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L0610 (from clone DKFZp434L0610); partial cds. /FEA=mRNA /GEN=DKFZp434L0610 /PROD=hypothetical protein /DB_XREF=gi:6808332 /UG=Hs.272813 dual oxidase 1 AL137592 dual oxidase 1 DUOX1 53905 NM_017434 /// NM_175940 /// XM_005254463 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0042335 // cuticle development // inferred from mutant phenotype /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0042554 // superoxide anion generation // non-traceable author statement /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // non-traceable author statement /// 0051591 // response to cAMP // inferred from direct assay /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // non-traceable author statement 0004601 // peroxidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016174 // NAD(P)H oxidase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // non-traceable author statement 215801_at AL133604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133604.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G1615 (from clone DKFZp434G1615). /FEA=mRNA /DB_XREF=gi:6599212 /UG=Hs.274568 Homo sapiens mRNA; cDNA DKFZp434G1615 (from clone DKFZp434G1615) AL133604 RP11-496I2.2 215802_at AK000144 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000144.1 /DEF=Homo sapiens cDNA FLJ20137 fis, clone COL07137. /FEA=mRNA /DB_XREF=gi:7020040 /UG=Hs.274449 Homo sapiens cDNA FLJ20137 fis, clone COL07137 AK000144 215803_at AK001040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001040.1 /DEF=Homo sapiens cDNA FLJ10178 fis, clone HEMBA1004146. /FEA=mRNA /DB_XREF=gi:7022064 /UG=Hs.274267 hypothetical protein FLJ10178 AK001040 chromosome X open reading frame 57 CXorf57 55086 NM_001184782 /// NM_018015 0044822 // poly(A) RNA binding // inferred from direct assay 215804_at Z27409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z27409.1 /DEF=H.sapiens mRNA for receptor tyrosine kinase eph (partial). /FEA=mRNA /PROD=receptor tyrosine kinase eph /DB_XREF=gi:482916 /UG=Hs.89839 EphA1 Z27409 EPH receptor A1 EPHA1 2041 NM_005232 /// XM_006715879 /// XM_006715880 /// XR_428169 0001525 // angiogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 215805_at BF574664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF574664 /FEA=EST /DB_XREF=gi:11648376 /DB_XREF=est:602132139F1 /CLONE=IMAGE:4271792 /UG=Hs.274531 Homo sapiens mRNA; cDNA DKFZp586F1024 (from clone DKFZp586F1024) BF574664 215806_x_at M13231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M13231.1 /DEF=Human T-cell receptor aberrantly rearranged gamma-chain mRNA from cell line HPB-MLT. /FEA=mRNA /DB_XREF=gi:339168 /UG=Hs.274509 T cell receptor gamma constant 2 M13231 TCR gamma alternate reading frame protein /// T cell receptor gamma constant 2 /// T cell receptor gamma variable 9 TARP /// TRGC2 /// TRGV9 6967 /// 6983 /// 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 215807_s_at AV693216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV693216 /FEA=EST /DB_XREF=gi:10295079 /DB_XREF=est:AV693216 /CLONE=GKCELF09 /UG=Hs.278311 plexin B1 AV693216 plexin B1 PLXNB1 5364 NM_001130082 /// NM_002673 /// XM_005265234 /// XM_006713206 /// XR_245138 /// XR_427278 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016477 // cell migration // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1900220 // semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // inferred from direct assay /// 0002116 // semaphorin receptor complex // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from direct assay /// 0017154 // semaphorin receptor activity // traceable author statement /// 0030215 // semaphorin receptor binding // traceable author statement /// 0032794 // GTPase activating protein binding // inferred from sequence or structural similarity 215808_at AK026045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026045.1 /DEF=Homo sapiens cDNA: FLJ22392 fis, clone HRC07868. /FEA=mRNA /DB_XREF=gi:10438761 /UG=Hs.275464 Homo sapiens cDNA: FLJ22392 fis, clone HRC07868 AK026045 kallikrein-related peptidase 10 KLK10 5655 NM_001077500 /// NM_002776 /// NM_145888 /// XM_005259061 /// XM_005259062 /// XM_006723287 /// XM_006723288 /// XM_006723289 0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 215809_at X16866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16866.1 /DEF=Human mRNA for cytochrome P-450IID (clone pMP33). /FEA=mRNA /DB_XREF=gi:35202 /UG=Hs.274598 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 7a (pseudogene) X16866 cytochrome P450, family 2, subfamily D, polypeptide 6 CYP2D6 1565 NM_000106 /// NM_001025161 /// XM_005278354 /// XM_006724157 /// XM_006726317 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0009820 // alkaloid metabolic process // inferred from direct assay /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0033076 // isoquinoline alkaloid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0051100 // negative regulation of binding // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0090350 // negative regulation of cellular organofluorine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 215810_x_at AL049215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049215.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B2416 (from clone DKFZp564B2416). /FEA=mRNA /DB_XREF=gi:4499945 /UG=Hs.278678 Dystonia musculorum of mouse, human homolog of AL049215 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 215811_at AF238870 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF238870.1 /DEF=Homo sapiens clone GLSH-3 similar to gliadin mRNA sequence. /FEA=mRNA /DB_XREF=gi:8272577 /UG=Hs.275706 Homo sapiens clone GLSH-3 similar to gliadin mRNA sequence AF238870 215812_s_at U41163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U41163 /DEF=Human creatine transporter (SLC6A10) gene, partial cds /FEA=CDS /DB_XREF=gi:1209100 /UG=Hs.275732 solute carrier family 6 (neurotransmitter transporter, creatine), member 10 U41163 solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene /// solute carrier family 6 (neurotransmitter transporter), member 8 pseudogene /// solute carrier family 6 (neurotransmitter transporter), member 8 SLC6A10P /// SLC6A10PB /// SLC6A8 6535 /// 386757 /// 653562 NM_001142805 /// NM_001142806 /// NM_005629 /// NM_198857 /// NR_003083 /// XR_426499 /// XR_430585 0006600 // creatine metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0015871 // choline transport // inferred from electronic annotation /// 0015881 // creatine transport // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // non-traceable author statement /// 1902598 // creatine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005308 // creatine transmembrane transporter activity // non-traceable author statement /// 0005309 // creatine:sodium symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 215813_s_at S36219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S36219.1 /DEF=prostaglandin GH synthase {alternative splicing product} human, lung fibroblast, clone HCO-T9, mRNA, 2324 nt. /FEA=mRNA /GEN=prostaglandin GH synthase, PGGHS /PROD=prostaglandin GH synthase /DB_XREF=gi:249623 /UG=Hs.88474 prostaglandin-endoperoxide synthase 1 (prostaglandin GH synthase and cyclooxygenase) S36219 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) PTGS1 5742 NM_000962 /// NM_001271164 /// NM_001271165 /// NM_001271166 /// NM_001271367 /// NM_001271368 /// NM_080591 /// XM_005252105 /// XM_006717192 0001516 // prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // inferred from direct assay /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity 0004601 // peroxidase activity // traceable author statement /// 0004666 // prostaglandin-endoperoxide synthase activity // inferred from direct assay /// 0004666 // prostaglandin-endoperoxide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 215814_at AL049215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049215.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B2416 (from clone DKFZp564B2416). /FEA=mRNA /DB_XREF=gi:4499945 /UG=Hs.278678 Dystonia musculorum of mouse, human homolog of AL049215 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 215815_at AK001615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001615.1 /DEF=Homo sapiens cDNA FLJ10753 fis, clone NT2RP3004539, highly similar to Homo sapiens mRNA for KIAA0632 protein. /FEA=mRNA /DB_XREF=gi:7022979 /UG=Hs.278317 KIAA0632 protein AK001615 BUD31 homolog (S. cerevisiae) BUD31 8896 NM_003910 /// XM_005250670 /// XM_005250671 /// XM_005250672 /// XM_005250673 /// XM_005250674 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 215816_at L02326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L02326 /DEF=Homo sapiens clone Hu lambda-17 lambda-like protein (IGLL2) gene, partial cds /FEA=CDS /DB_XREF=gi:292400 /UG=Hs.278451 Homo sapiens clone Hu lambda-17 lambda-like protein (IGLL2) gene, partial cds L02326 glucuronidase, beta pseudogene 11 GUSBP11 91316 NR_024448 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation 215817_at BE148534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE148534 /FEA=EST /DB_XREF=gi:8611258 /DB_XREF=est:MR0-HT0241-030200-008-h03 /UG=Hs.84168 UV-B repressed sequence, HUR 7 BE148534 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 215818_at AK026469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026469.1 /DEF=Homo sapiens cDNA: FLJ22816 fis, clone KAIA3155. /FEA=mRNA /DB_XREF=gi:10439340 /UG=Hs.282979 Homo sapiens cDNA: FLJ22816 fis, clone KAIA3155 AK026469 nudix (nucleoside diphosphate linked moiety X)-type motif 7 NUDT7 283927 NM_001105663 /// NM_001243657 /// NM_001243660 /// NM_001243661 0009132 // nucleoside diphosphate metabolic process // inferred from electronic annotation /// 0015938 // coenzyme A catabolic process // inferred from sequence or structural similarity /// 0046356 // acetyl-CoA catabolic process // inferred from sequence or structural similarity /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005777 // peroxisome // inferred from sequence or structural similarity 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003986 // acetyl-CoA hydrolase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030515 // snoRNA binding // inferred from sequence or structural similarity /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from sequence or structural similarity 215819_s_at N53959 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N53959 /FEA=EST /DB_XREF=gi:1195125 /DB_XREF=est:yv60b12.s1 /CLONE=IMAGE:247103 /UG=Hs.278994 Rhesus blood group, CcEe antigens N53959 Rh blood group, CcEe antigens /// Rh blood group, D antigen RHCE /// RHD 6006 /// 6007 NM_001127691 /// NM_001282867 /// NM_001282868 /// NM_001282869 /// NM_001282870 /// NM_001282871 /// NM_001282872 /// NM_016124 /// NM_016225 /// NM_020485 /// NM_138616 /// NM_138617 /// NM_138618 /// XM_005245957 /// XM_006710810 0015696 // ammonium transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from electronic annotation 215820_x_at AK001861 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001861.1 /DEF=Homo sapiens cDNA FLJ10999 fis, clone PLACE1002529, highly similar to Homo sapiens mRNA for KIAA0713 protein. /FEA=mRNA /DB_XREF=gi:7023392 /UG=Hs.283881 KIAA0713 protein AK001861 sorting nexin 13 SNX13 23161 NM_015132 /// XM_005249672 /// XM_005249673 /// XM_005249674 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 215821_x_at R32065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R32065 /FEA=EST /DB_XREF=gi:787908 /DB_XREF=est:yh63c07.r1 /CLONE=IMAGE:134412 /UG=Hs.282847 pregnancy specific beta-1-glycoprotein 3 R32065 pregnancy specific beta-1-glycoprotein 11 /// pregnancy specific beta-1-glycoprotein 3 PSG11 /// PSG3 5671 /// 5680 NM_001113410 /// NM_002785 /// NM_021016 /// NM_203287 0006952 // defense response // traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 215822_x_at M96980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M96980.1 /DEF=Homo sapiens myelin transcription factor 1 (MTF1) mRNA, 3 end. /FEA=mRNA /GEN=MTF1 /PROD=myelin transcription factor 1 /DB_XREF=gi:189041 /UG=Hs.279562 myelin transcription factor 1 M96980 myelin transcription factor 1 MYT1 4661 NM_004535 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 215823_x_at U64661 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U64661 /DEF=Human poly(A)-binding protein processed pseudogene3 /FEA=mRNA /DB_XREF=gi:1519214 /UG=Hs.283767 poly(A)-binding protein, cytoplasmic, pseudogene 3 U64661 poly(A) binding protein, cytoplasmic 1 /// ring finger protein, LIM domain interacting PABPC1 /// RLIM 26986 /// 51132 NM_002568 /// NM_016120 /// NM_183353 /// XM_005250861 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0048255 // mRNA stabilization // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from sequence or structural similarity /// 0060816 // random inactivation of X chromosome // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0017053 // transcriptional repressor complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008143 // poly(A) binding // traceable author statement /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008494 // translation activator activity // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215824_at AK026469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026469.1 /DEF=Homo sapiens cDNA: FLJ22816 fis, clone KAIA3155. /FEA=mRNA /DB_XREF=gi:10439340 /UG=Hs.282979 Homo sapiens cDNA: FLJ22816 fis, clone KAIA3155 AK026469 215825_at AF070579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070579.1 /DEF=Homo sapiens clone 24487 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387951 /UG=Hs.283819 Homo sapiens clone 24487 mRNA sequence AF070579 RP11-255C15.3 215826_x_at AK023017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023017.1 /DEF=Homo sapiens cDNA FLJ12955 fis, clone NT2RP2005496, moderately similar to ZINC FINGER PROTEIN 135. /FEA=mRNA /DB_XREF=gi:10434737 /UG=Hs.283877 Homo sapiens cDNA FLJ12955 fis, clone NT2RP2005496, moderately similar to ZINC FINGER PROTEIN 135 AK023017 zinc finger protein 835 ZNF835 90485 NM_001005850 /// XM_005259382 /// XM_005259383 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215827_x_at BE300056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE300056 /FEA=EST /DB_XREF=gi:9183804 /DB_XREF=est:600944513T1 /CLONE=IMAGE:2960715 /UG=Hs.283848 Human DNA sequence from clone RP4-798A10 on chromosome 1 Contains part of a gene for a novel protein, part of the gene for KIAA0445 protein and CpG islands BE300056 ciliary rootlet coiled-coil, rootletin pseudogene 3 CROCCP3 114819 NR_023386 0051297 // centrosome organization // inferred from electronic annotation 0035253 // ciliary rootlet // inferred from electronic annotation 215828_at AL359599 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359599.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547C126 (from clone DKFZp547C126). /FEA=mRNA /DB_XREF=gi:8655666 /UG=Hs.283850 Homo sapiens mRNA; cDNA DKFZp547C126 (from clone DKFZp547C126) AL359599 215829_at AF141901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF141901.1 /DEF=Homo sapiens GKAPSAPAP interacting protein (SHANK) mRNA, partial cds. /FEA=mRNA /GEN=SHANK /PROD=GKAPSAPAP interacting protein /DB_XREF=gi:6049185 /UG=Hs.283895 Homo sapiens GKAPSAPAP interacting protein (SHANK) mRNA, partial cds AF141901 SH3 and multiple ankyrin repeat domains 2 SHANK2 22941 NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity 215830_at AF141901 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF141901.1 /DEF=Homo sapiens GKAPSAPAP interacting protein (SHANK) mRNA, partial cds. /FEA=mRNA /GEN=SHANK /PROD=GKAPSAPAP interacting protein /DB_XREF=gi:6049185 /UG=Hs.283895 Homo sapiens GKAPSAPAP interacting protein (SHANK) mRNA, partial cds AF141901 Homo sapiens cDNA clone IMAGE:40054126. /// SH3 and multiple ankyrin repeat domains 2 BC127192 /// SHANK2 22941 NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity 215831_at AF113018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113018.1 /DEF=Homo sapiens clone FLB6230 mRNA sequence. /FEA=mRNA /DB_XREF=gi:6642759 /UG=Hs.284302 PRO1621 protein AF113018 215832_x_at AV722190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV722190 /FEA=EST /DB_XREF=gi:10824430 /DB_XREF=est:AV722190 /CLONE=HTBAMF09 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein AV722190 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 215833_s_at AC004410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004410 /DEF=Homo sapiens chromosome 19, fosmid 39554 /FEA=CDS /DB_XREF=gi:2959558 /UG=Hs.284161 hypothetical protein from EUROIMAGE 42353 AC004410 signal peptide peptidase like 2B SPPL2B 56928 NM_001077238 /// NM_152988 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // inferred from mutant phenotype /// 0050776 // regulation of immune response // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0071458 // integral component of cytoplasmic side of endoplasmic reticulum membrane // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042500 // aspartic endopeptidase activity, intramembrane cleaving // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay 215834_x_at AV708130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV708130 /FEA=EST /DB_XREF=gi:10725395 /DB_XREF=est:AV708130 /CLONE=ADCAMA05 /UG=Hs.283965 Homo sapiens scavenger receptor class B type III SR-BIII mRNA, partial cds AV708130 scavenger receptor class B, member 1 SCARB1 949 NM_001082959 /// NM_005505 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0044406 // adhesion of symbiont to host // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001786 // phosphatidylserine binding // inferred from sequence or structural similarity /// 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0070506 // high-density lipoprotein particle receptor activity // inferred from direct assay 215835_at AV708130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV708130 /FEA=EST /DB_XREF=gi:10725395 /DB_XREF=est:AV708130 /CLONE=ADCAMA05 /UG=Hs.283965 Homo sapiens scavenger receptor class B type III SR-BIII mRNA, partial cds AV708130 scavenger receptor class B, member 1 SCARB1 949 NM_001082959 /// NM_005505 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0044406 // adhesion of symbiont to host // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001786 // phosphatidylserine binding // inferred from sequence or structural similarity /// 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0070506 // high-density lipoprotein particle receptor activity // inferred from direct assay 215836_s_at AK026188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026188.1 /DEF=Homo sapiens cDNA: FLJ22535 fis, clone HRC13115, highly similar to AF152336 Homo sapiens protocadherin gamma B7 (PCDH-gamma-B7) mRNA. /FEA=mRNA /DB_XREF=gi:10438958 /UG=Hs.284180 protocadherin gamma subfamily A, 1 AK026188 protocadherin gamma subfamily A, 1 /// protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 2 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 4 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily A, 7 /// protocadherin gamma subfamily A, 8 /// protocadherin gamma subfamily A, 9 /// protocadherin gamma subfamily B, 1 /// protocadherin gamma subfamily B, 2 /// protocadherin gamma subfamily B, 3 /// protocadherin gamma subfamily B, 4 /// protocadherin gamma subfamily B, 5 /// protocadherin gamma subfamily B, 6 /// protocadherin gamma subfamily B, 7 /// protocadherin gamma subfamily C, 3 /// protocadherin gamma subfamily C, 4 /// protocadherin gamma subfamily C, 5 PCDHGA1 /// PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA2 /// PCDHGA3 /// PCDHGA4 /// PCDHGA5 /// PCDHGA6 /// PCDHGA7 /// PCDHGA8 /// PCDHGA9 /// PCDHGB1 /// PCDHGB2 /// PCDHGB3 /// PCDHGB4 /// PCDHGB5 /// PCDHGB6 /// PCDHGB7 /// PCDHGC3 /// PCDHGC4 /// PCDHGC5 5098 /// 8641 /// 9708 /// 26025 /// 56097 /// 56098 /// 56099 /// 56100 /// 56101 /// 56102 /// 56103 /// 56104 /// 56105 /// 56106 /// 56107 /// 56108 /// 56109 /// 56110 /// 56111 /// 56112 /// 56113 /// 56114 NM_002588 /// NM_003735 /// NM_003736 /// NM_014004 /// NM_018912 /// NM_018913 /// NM_018914 /// NM_018915 /// NM_018916 /// NM_018917 /// NM_018918 /// NM_018919 /// NM_018920 /// NM_018921 /// NM_018922 /// NM_018923 /// NM_018924 /// NM_018925 /// NM_018926 /// NM_018927 /// NM_018928 /// NM_018929 /// NM_031993 /// NM_032009 /// NM_032011 /// NM_032053 /// NM_032054 /// NM_032086 /// NM_032087 /// NM_032088 /// NM_032089 /// NM_032090 /// NM_032091 /// NM_032092 /// NM_032094 /// NM_032095 /// NM_032096 /// NM_032097 /// NM_032098 /// NM_032099 /// NM_032100 /// NM_032101 /// NM_032402 /// NM_032403 /// NM_032406 /// NM_032407 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215837_x_at AF113018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113018.1 /DEF=Homo sapiens clone FLB6230 mRNA sequence. /FEA=mRNA /DB_XREF=gi:6642759 /UG=Hs.284302 PRO1621 protein AF113018 215838_at AF212842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF212842.1 /DEF=Homo sapiens immunoglobulin-like transcript 11 protein (ILT11) mRNA, partial cds. /FEA=mRNA /GEN=ILT11 /PROD=immunoglobulin-like transcript 11 protein /DB_XREF=gi:8163785 /UG=Hs.284190 immunoglobulin-like transcript 11 protein AF212842 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 LILRA5 353514 NM_021250 /// NM_181879 /// NM_181985 /// NM_181986 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215839_at AF212842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF212842.1 /DEF=Homo sapiens immunoglobulin-like transcript 11 protein (ILT11) mRNA, partial cds. /FEA=mRNA /GEN=ILT11 /PROD=immunoglobulin-like transcript 11 protein /DB_XREF=gi:8163785 /UG=Hs.284190 immunoglobulin-like transcript 11 protein AF212842 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 LILRA5 353514 NM_021250 /// NM_181879 /// NM_181985 /// NM_181986 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215840_at AB040936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040936.1 /DEF=Homo sapiens mRNA for KIAA1503 protein, partial cds. /FEA=mRNA /GEN=KIAA1503 /PROD=KIAA1503 protein /DB_XREF=gi:7959266 /UG=Hs.284274 KIAA1503 protein AB040936 dynein, axonemal, heavy chain 2 DNAH2 146754 NM_020877 /// XM_005256470 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 215841_at AL096814 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096814 /DEF=Human DNA sequence from clone RP1-139D8 on chromosome 6p12.1-21.1 Contains genes for GUCA1A (guanylate cyclase activator 1A) and GUCA1B (guanylate cyclase activator 1B) both from retina, ESTs, STSs, GSSs and CpG Islands /FEA=mRNA_1 /DB_XREF=gi:7159757 /UG=Hs.284258 Human DNA sequence from clone RP1-139D8 on chromosome 6p12.1-21.1 Contains genes for GUCA1A (guanylate cyclase activator 1A) and GUCA1B (guanylate cyclase activator 1B) both from retina, ESTs, STSs, GSSs and CpG Islands AL096814 guanylate cyclase activator 1B (retina) GUCA1B 2979 NM_002098 0007168 // receptor guanylyl cyclase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007589 // body fluid secretion // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215842_s_at AK024264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024264.1 /DEF=Homo sapiens cDNA FLJ14202 fis, clone NT2RP3002985. /FEA=mRNA /DB_XREF=gi:10436598 /UG=Hs.29189 ATPase, Class VI, type 11A AK024264 ATPase, class VI, type 11A ATP11A 23250 NM_015205 /// NM_032189 /// XM_005268299 /// XM_005268300 /// XM_005268301 /// XM_005268303 /// XM_005268305 /// XM_005268306 /// XM_006719965 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215843_s_at AK026106 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026106.1 /DEF=Homo sapiens cDNA: FLJ22453 fis, clone HRC09679, highly similar to AF059516 Homo sapiens tolloid-like 2 protein (TLL2) mRNA. /FEA=mRNA /DB_XREF=gi:10438849 /UG=Hs.287695 Homo sapiens cDNA: FLJ22453 fis, clone HRC09679, highly similar to AF059516 Homo sapiens tolloid-like 2 protein (TLL2) mRNA AK026106 tolloid-like 2 TLL2 7093 NM_012465 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215844_at AK022217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022217.1 /DEF=Homo sapiens cDNA FLJ12155 fis, clone MAMMA1000472. /FEA=mRNA /DB_XREF=gi:10433566 /UG=Hs.287494 Homo sapiens cDNA FLJ12155 fis, clone MAMMA1000472 AK022217 transportin 2 TNPO2 30000 NM_001136195 /// NM_001136196 /// NM_013433 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 215845_x_at AK026493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026493.1 /DEF=Homo sapiens cDNA: FLJ22840 fis, clone KAIA4709. /FEA=mRNA /DB_XREF=gi:10439366 /UG=Hs.287293 Homo sapiens cDNA: FLJ22840 fis, clone KAIA4709 AK026493 215846_at AL117571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117571.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564O1172 (from clone DKFZp564O1172). /FEA=mRNA /DB_XREF=gi:5912123 /UG=Hs.241562 Homo sapiens mRNA; cDNA DKFZp564O1172 (from clone DKFZp564O1172) AL117571 215847_at BC000975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000975.2 /DEF=Homo sapiens, clone IMAGE:3448306, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3448306) /DB_XREF=gi:12803026 /UG=Hs.286132 D15F37 (pseudogene) BC000975 hect domain and RLD 2 pseudogene 3 /// uncharacterized LOC101930458 HERC2P3 /// LOC101930458 283755 /// 101930458 NM_001024682 /// NR_036432 /// XR_248072 0016567 // protein ubiquitination // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215848_at AW139369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139369 /FEA=EST /DB_XREF=gi:6144087 /DB_XREF=est:UI-H-BI1-adq-a-04-0-UI.s1 /CLONE=IMAGE:2717478 /UG=Hs.285848 KIAA1454 protein AW139369 S-phase cyclin A-associated protein in the ER SCAPER 49855 NM_001145923 /// NM_020843 /// XM_005254417 /// XM_005254419 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 215849_x_at AK022235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022235.1 /DEF=Homo sapiens cDNA FLJ12173 fis, clone MAMMA1000696. /FEA=mRNA /DB_XREF=gi:10433588 /UG=Hs.306630 Homo sapiens cDNA FLJ12173 fis, clone MAMMA1000696 AK022235 tetratricopeptide repeat domain 18 TTC18 118491 NM_145170 /// XM_005269488 /// XM_005269489 /// XM_006717604 /// XM_006717605 /// XM_006717606 /// XM_006717607 /// XM_006717608 /// XM_006717609 /// XM_006717610 /// XM_006717611 /// XM_006717612 /// XM_006717613 /// XM_006717614 /// XR_428694 /// XR_428695 0070062 // extracellular vesicular exosome // inferred from direct assay 215850_s_at AK022209 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022209.1 /DEF=Homo sapiens cDNA FLJ12147 fis, clone MAMMA1000410. /FEA=mRNA /DB_XREF=gi:10433554 /UG=Hs.287492 Homo sapiens cDNA FLJ12147 fis, clone MAMMA1000410 AK022209 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 NDUFA5 4698 NM_001282419 /// NM_001282420 /// NM_001282421 /// NM_001282422 /// NM_001291304 /// NM_005000 /// NR_104168 /// NR_104169 /// NR_111925 /// NR_111926 /// XM_005250371 /// XR_426239 /// XR_428243 /// XR_432226 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation 215851_at S82592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S82592.1 /DEF=Evi-1=Evi-1 protein {3 region, deletion region} human, megakaryoblastoid cell line MOLM-1, chronic myelocytic leukemia patient, mRNA Partial Mutant, 916 nt. /FEA=mRNA /GEN=Evi-1 /PROD=Evi-1 protein /DB_XREF=gi:1699292 /UG=Hs.287359 ecotropic viral integration site 1 S82592 MDS1 and EVI1 complex locus MECOM 2122 NM_001105077 /// NM_001105078 /// NM_001163999 /// NM_001164000 /// NM_001205194 /// NM_004991 /// NM_005241 /// XM_005247213 /// XM_005247214 /// XM_005247215 /// XM_005247216 /// XM_005247219 /// XM_005247220 /// XM_005247221 /// XM_005247223 /// XM_005247224 /// XM_005247225 /// XM_005247226 /// XM_006713536 /// XM_006713537 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060039 // pericardium development // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215852_x_at AK022023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022023.1 /DEF=Homo sapiens cDNA FLJ11961 fis, clone HEMBB1001020, highly similar to Homo sapiens mRNA for KIAA0889 protein. /FEA=mRNA /DB_XREF=gi:10433337 /UG=Hs.287469 Homo sapiens cDNA FLJ11961 fis, clone HEMBB1001020, highly similar to Homo sapiens mRNA for KIAA0889 protein AK022023 suppressor of glucose, autophagy associated 1 SOGA1 140710 NM_080627 /// NM_152257 /// NM_199181 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 215853_at AK021640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021640.1 /DEF=Homo sapiens cDNA FLJ11578 fis, clone HEMBA1003571. /FEA=mRNA /DB_XREF=gi:10432861 /UG=Hs.287427 Homo sapiens cDNA FLJ11578 fis, clone HEMBA1003571 AK021640 215854_at AU146050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146050 /FEA=EST /DB_XREF=gi:11007571 /DB_XREF=est:AU146050 /CLONE=HEMBA1006665 /UG=Hs.287459 Homo sapiens cDNA FLJ11844 fis, clone HEMBA1006665 AU146050 215855_s_at AK021741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021741.1 /DEF=Homo sapiens cDNA FLJ11679 fis, clone HEMBA1004807. /FEA=mRNA /DB_XREF=gi:10432986 /UG=Hs.287439 Homo sapiens cDNA FLJ11679 fis, clone HEMBA1004807 AK021741 TATA element modulatory factor 1 TMF1 7110 NM_007114 0001675 // acrosome assembly // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0032275 // luteinizing hormone secretion // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2000845 // positive regulation of testosterone secretion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215856_at AK025833 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025833.1 /DEF=Homo sapiens cDNA: FLJ22180 fis, clone HRC00936. /FEA=mRNA /DB_XREF=gi:10438467 /UG=Hs.287692 Homo sapiens cDNA: FLJ22180 fis, clone HRC00936 AK025833 sialic acid binding Ig-like lectin 15 SIGLEC15 284266 NM_213602 /// XM_005258249 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045124 // regulation of bone resorption // inferred from electronic annotation /// 0071402 // cellular response to lipoprotein particle stimulus // inferred from electronic annotation /// 2001204 // regulation of osteoclast development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 215857_at AK022309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022309.1 /DEF=Homo sapiens cDNA FLJ12247 fis, clone MAMMA1001397. /FEA=mRNA /DB_XREF=gi:10433678 /UG=Hs.287506 Homo sapiens cDNA FLJ12247 fis, clone MAMMA1001397 AK022309 nicalin NCLN 56926 NM_020170 /// XM_005259596 0006508 // proteolysis // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation 215858_at AK022363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022363.1 /DEF=Homo sapiens cDNA FLJ12301 fis, clone MAMMA1001858. /FEA=mRNA /DB_XREF=gi:10433745 /UG=Hs.287511 Homo sapiens cDNA FLJ12301 fis, clone MAMMA1001858 AK022363 215859_at AK022309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022309.1 /DEF=Homo sapiens cDNA FLJ12247 fis, clone MAMMA1001397. /FEA=mRNA /DB_XREF=gi:10433678 /UG=Hs.287506 Homo sapiens cDNA FLJ12247 fis, clone MAMMA1001397 AK022309 nicalin NCLN 56926 NM_020170 /// XM_005259596 0006508 // proteolysis // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation 215860_at AU158606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158606 /FEA=EST /DB_XREF=gi:11020127 /DB_XREF=est:AU158606 /CLONE=PLACE3000406 /UG=Hs.287636 Homo sapiens cDNA FLJ14319 fis, clone PLACE3000406 AU158606 synaptotagmin XII SYT12 91683 NM_001177880 /// NM_177963 /// XM_006718737 0006810 // transport // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 215861_at AK024093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024093.1 /DEF=Homo sapiens cDNA FLJ14031 fis, clone HEMBA1004335. /FEA=mRNA /DB_XREF=gi:10436386 /UG=Hs.287615 hypothetical protein FLJ14031 AK024093 uncharacterized LOC101927770 LOC101927770 101927770 NR_110051 215862_at AK022363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022363.1 /DEF=Homo sapiens cDNA FLJ12301 fis, clone MAMMA1001858. /FEA=mRNA /DB_XREF=gi:10433745 /UG=Hs.287511 Homo sapiens cDNA FLJ12301 fis, clone MAMMA1001858 AK022363 215863_at AK022002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022002.1 /DEF=Homo sapiens cDNA FLJ11940 fis, clone HEMBB1000593, highly similar to Homo sapiens transferrin receptor 2 alpha (TFR2) mRNA. /FEA=mRNA /DB_XREF=gi:10433313 /UG=Hs.63758 transferrin receptor 2 AK022002 transferrin receptor 2 TFR2 7036 NM_001206855 /// NM_003227 /// XM_005250553 /// XM_005250554 /// XM_006716103 0006508 // proteolysis // inferred from electronic annotation /// 0006826 // iron ion transport // non-traceable author statement /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004998 // transferrin receptor activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation 215864_at AK025077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025077.1 /DEF=Homo sapiens cDNA: FLJ21424 fis, clone COL04157. /FEA=mRNA /DB_XREF=gi:10437519 /UG=Hs.287662 Homo sapiens cDNA: FLJ21424 fis, clone COL04157 AK025077 215865_at AK024381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024381.1 /DEF=Homo sapiens cDNA FLJ14319 fis, clone PLACE3000406. /FEA=mRNA /DB_XREF=gi:10436753 /UG=Hs.287636 Homo sapiens cDNA FLJ14319 fis, clone PLACE3000406 AK024381 synaptotagmin XII SYT12 91683 NM_001177880 /// NM_177963 /// XM_006718737 0006810 // transport // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 215866_at AK024938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024938.1 /DEF=Homo sapiens cDNA: FLJ21285 fis, clone COL01912. /FEA=mRNA /DB_XREF=gi:10437359 /UG=Hs.287655 Homo sapiens cDNA: FLJ21285 fis, clone COL01912 AK024938 215867_x_at AL050025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050025.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D066 (from clone DKFZp564D066); partial cds. /FEA=mRNA /GEN=DKFZp564D066 /PROD=hypothetical protein /DB_XREF=gi:4884095 /UG=Hs.5344 adaptor-related protein complex 1, gamma 1 subunit AL050025 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032438 // melanosome organization // inferred by curator /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215868_x_at AK026238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026238.1 /DEF=Homo sapiens cDNA: FLJ22585 fis, clone HSI02678. /FEA=mRNA /DB_XREF=gi:10439027 /UG=Hs.287701 Homo sapiens cDNA: FLJ22585 fis, clone HSI02678 AK026238 215869_at AK022254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022254.1 /DEF=Homo sapiens cDNA FLJ12192 fis, clone MAMMA1000851. /FEA=mRNA /DB_XREF=gi:10433612 /UG=Hs.288451 Homo sapiens cDNA FLJ12192 fis, clone MAMMA1000851 AK022254 215870_s_at AL158172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL158172 /DEF=Human DNA sequence from clone RP1-169O23 on chromosome 1 Contains ESTs, STSs and GSSs. Contains the PLA2G5 gene for two isoforms of phospholiapse A2 group V, a novel gene, the PLA2G2D gene for phospholipade 2 group IID and the 5 part of the gene ... /FEA=mRNA_4 /DB_XREF=gi:9801324 /UG=Hs.290 phospholipase A2, group V AL158172 phospholipase A2, group V PLA2G5 5322 NM_000929 /// XM_005245891 /// XM_005245892 /// XM_005245893 /// XM_005245895 /// XM_005245896 /// XM_006710691 /// XM_006710692 /// XM_006710693 /// XM_006710694 /// XM_006710695 /// XM_006710696 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006663 // platelet activating factor biosynthetic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from electronic annotation 215871_at AL158172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL158172 /DEF=Human DNA sequence from clone RP1-169O23 on chromosome 1 Contains ESTs, STSs and GSSs. Contains the PLA2G5 gene for two isoforms of phospholiapse A2 group V, a novel gene, the PLA2G2D gene for phospholipade 2 group IID and the 5 part of the gene ... /FEA=mRNA_4 /DB_XREF=gi:9801324 /UG=Hs.290 phospholipase A2, group V AL158172 phospholipase A2, group V PLA2G5 5322 NM_000929 /// XM_005245891 /// XM_005245892 /// XM_005245893 /// XM_005245895 /// XM_005245896 /// XM_006710691 /// XM_006710692 /// XM_006710693 /// XM_006710694 /// XM_006710695 /// XM_006710696 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006663 // platelet activating factor biosynthetic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from electronic annotation 215872_at AK024445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024445.1 /DEF=Homo sapiens mRNA for FLJ00035 protein, partial cds. /FEA=mRNA /GEN=FLJ00035 /PROD=FLJ00035 protein /DB_XREF=gi:10440403 /UG=Hs.287752 Homo sapiens mRNA for FLJ00035 protein, partial cds AK024445 RP6-91H8.1 215873_x_at AK024446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024446.1 /DEF=Homo sapiens mRNA for FLJ00036 protein, partial cds. /FEA=mRNA /GEN=FLJ00036 /PROD=FLJ00036 protein /DB_XREF=gi:10440405 /UG=Hs.55879 hypothetical protein MGC2487 AK024446 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 ABCC10 89845 NM_001198934 /// NM_033450 /// XM_005249470 /// XM_006715240 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 215874_at AK026820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026820.1 /DEF=Homo sapiens cDNA: FLJ23167 fis, clone LNG09902. /FEA=mRNA /DB_XREF=gi:10439765 /UG=Hs.287730 Homo sapiens cDNA: FLJ23167 fis, clone LNG09902 AK026820 215875_at AK026820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026820.1 /DEF=Homo sapiens cDNA: FLJ23167 fis, clone LNG09902. /FEA=mRNA /DB_XREF=gi:10439765 /UG=Hs.287730 Homo sapiens cDNA: FLJ23167 fis, clone LNG09902 AK026820 215876_at AK022254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022254.1 /DEF=Homo sapiens cDNA FLJ12192 fis, clone MAMMA1000851. /FEA=mRNA /DB_XREF=gi:10433612 /UG=Hs.288451 Homo sapiens cDNA FLJ12192 fis, clone MAMMA1000851 AK022254 RP11-217B7.2 215877_at AK024445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024445.1 /DEF=Homo sapiens mRNA for FLJ00035 protein, partial cds. /FEA=mRNA /GEN=FLJ00035 /PROD=FLJ00035 protein /DB_XREF=gi:10440403 /UG=Hs.287752 Homo sapiens mRNA for FLJ00035 protein, partial cds AK024445 215878_at BG435463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG435463 /FEA=EST /DB_XREF=gi:13341969 /DB_XREF=est:602507051F1 /CLONE=IMAGE:4604173 /UG=Hs.287798 Human integrin beta-1 subunit mRNA, 3 end (cytoplasmic domain) BG435463 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ITGB1 3688 NM_002211 /// NM_033666 /// NM_033667 /// NM_033668 /// NM_033669 /// NM_133376 /// XM_005252448 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007161 // calcium-independent cell-matrix adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032594 // protein transport within lipid bilayer // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001726 // ruffle // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0001968 // fibronectin binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation 215879_at M34189 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M34189.1 /DEF=Human integrin beta-1 subunit mRNA, 3 end (cytoplasmic domain). /FEA=mRNA /GEN=ITGB1 /DB_XREF=gi:186500 /UG=Hs.287798 Human integrin beta-1 subunit mRNA, 3 end (cytoplasmic domain) M34189 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ITGB1 3688 NM_002211 /// NM_033666 /// NM_033667 /// NM_033668 /// NM_033669 /// NM_133376 /// XM_005252448 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007161 // calcium-independent cell-matrix adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032594 // protein transport within lipid bilayer // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001726 // ruffle // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0001968 // fibronectin binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation 215880_at AI364950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI364950 /FEA=EST /DB_XREF=gi:4124639 /DB_XREF=est:qz41e06.x1 /CLONE=IMAGE:2029474 /UG=Hs.50727 N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) AI364950 N-acetylglucosaminidase, alpha NAGLU 4669 NM_000263 /// XM_006721920 /// XM_006721921 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004561 // alpha-N-acetylglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 215881_x_at BF184274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF184274 /FEA=EST /DB_XREF=gi:11062646 /DB_XREF=est:601843339F1 /CLONE=IMAGE:4064072 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 BF184274 synovial sarcoma, X breakpoint 2 /// synovial sarcoma, X breakpoint 2B /// synovial sarcoma, X breakpoint 3 SSX2 /// SSX2B /// SSX3 6757 /// 10214 /// 727837 NM_001164417 /// NM_001278697 /// NM_001278701 /// NM_001278702 /// NM_003147 /// NM_021014 /// NM_175698 /// NM_175711 /// XM_005272579 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 215882_at AK025247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025247.1 /DEF=Homo sapiens cDNA: FLJ21594 fis, clone COL07053. /FEA=mRNA /DB_XREF=gi:10437718 /UG=Hs.288571 Homo sapiens cDNA: FLJ21594 fis, clone COL07053 AK025247 centrosomal protein 152kDa CEP152 22995 NM_001194998 /// NM_014985 /// XM_006720437 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0098535 // de novo centriole assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0098536 // deuterosome // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 215883_at AK022326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022326.1 /DEF=Homo sapiens cDNA FLJ12264 fis, clone MAMMA1001600. /FEA=mRNA /DB_XREF=gi:10433699 /UG=Hs.288481 Homo sapiens cDNA FLJ12264 fis, clone MAMMA1001600 AK022326 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 215884_s_at AK001029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001029.1 /DEF=Homo sapiens cDNA FLJ10167 fis, clone HEMBA1003617, highly similar to Homo sapiens HRIHFB2157 mRNA. /FEA=mRNA /DB_XREF=gi:7022050 /UG=Hs.4552 ubiquilin 2 AK001029 ubiquilin 2 UBQLN2 29978 NM_013444 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215885_at BF184274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF184274 /FEA=EST /DB_XREF=gi:11062646 /DB_XREF=est:601843339F1 /CLONE=IMAGE:4064072 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 BF184274 synovial sarcoma, X breakpoint 2B SSX2B 727837 NM_001164417 /// NM_001278701 /// NM_001278702 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 215886_x_at AF022790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF022790 /DEF=Homo sapiens ubiquitin hydrolyzing enzyme I (UBH1) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3213205 /UG=Hs.42400 ubiquitin specific protease 12 AF022790 ubiquitin specific peptidase 12 USP12 219333 NM_182488 /// XM_005266282 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 215887_at AK027128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027128.1 /DEF=Homo sapiens cDNA: FLJ23475 fis, clone HSI13659. /FEA=mRNA /DB_XREF=gi:10440177 /UG=Hs.288982 Homo sapiens cDNA: FLJ23475 fis, clone HSI13659 AK027128 zinc finger protein 277 ZNF277 11179 NM_021994 /// XM_005250129 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215888_at AK026889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026889.1 /DEF=Homo sapiens cDNA: FLJ23236 fis, clone COL00725. /FEA=mRNA /DB_XREF=gi:10439854 /UG=Hs.288786 Homo sapiens cDNA: FLJ23236 fis, clone COL00725 AK026889 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) PDS5B 23047 NM_015032 /// NM_015928 /// XM_005266295 /// XM_005266296 /// XM_005266297 /// XM_005266298 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007064 // mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement 215889_at X15217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X15217.1 /DEF=Human sno oncogene mRNA for snoA protein, ski-related. /FEA=mRNA /DB_XREF=gi:36508 /UG=Hs.38783 SKI-like X15217 SKI-like proto-oncogene SKIL 6498 NM_001145097 /// NM_001145098 /// NM_001248008 /// NM_005414 /// XM_005247721 /// XM_006713735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0046677 // response to antibiotic // inferred from expression pattern /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from mutant phenotype /// 0070207 // protein homotrimerization // inferred from direct assay /// 0070208 // protein heterotrimerization // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction 215890_at X61094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61094.1 /DEF=H.sapiens RNA for GM2-activator protein (clone pGM2A). /FEA=mRNA /PROD=GM2-activator protein /DB_XREF=gi:31854 /UG=Hs.289082 GM2 ganglioside activator protein X61094 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 215891_s_at X61094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61094.1 /DEF=H.sapiens RNA for GM2-activator protein (clone pGM2A). /FEA=mRNA /PROD=GM2-activator protein /DB_XREF=gi:31854 /UG=Hs.289082 GM2 ganglioside activator protein X61094 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019377 // glycolipid catabolic process // non-traceable author statement /// 0019915 // lipid storage // inferred from electronic annotation /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030290 // sphingolipid activator protein activity // non-traceable author statement 215892_at AK021474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021474.1 /DEF=Homo sapiens cDNA FLJ11412 fis, clone HEMBA1000876. /FEA=mRNA /DB_XREF=gi:10432666 /UG=Hs.289094 Homo sapiens cDNA FLJ11412 fis, clone HEMBA1000876 AK021474 zinc finger protein 440 ZNF440 126070 NM_152357 /// XM_005259731 /// XM_006722641 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215893_x_at AF339787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339787.1 /DEF=Homo sapiens clone IMAGE:205688, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507325 /UG=Hs.326722 Homo sapiens clone IMAGE:205688, mRNA sequence AF339787 215894_at AI460323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI460323 /FEA=EST /DB_XREF=gi:4313204 /DB_XREF=est:ao95a01.x1 /CLONE=IMAGE:1953576 /UG=Hs.158326 prostaglandin D2 receptor (DP) AI460323 prostaglandin D2 receptor (DP) PTGDR 5729 NM_000953 /// NM_001281469 /// XM_005267891 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0030238 // male sex determination // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001785 // prostaglandin J receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004956 // prostaglandin D receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215895_x_at AK022061 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022061.1 /DEF=Homo sapiens cDNA FLJ11999 fis, clone HEMBB1001527. /FEA=mRNA /DB_XREF=gi:10433381 /UG=Hs.306622 Homo sapiens cDNA FLJ11999 fis, clone HEMBB1001527 AK022061 perilipin 2 PLIN2 123 NM_001122 /// NR_038064 /// XM_006716719 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 215896_at AU144277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144277 /FEA=EST /DB_XREF=gi:11005798 /DB_XREF=est:AU144277 /CLONE=HEMBA1001415 /UG=Hs.296525 Homo sapiens cDNA FLJ10062 fis, clone HEMBA1001415 AU144277 215897_at AF283769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF283769.2 /DEF=Homo sapiens clone TCBAP0758 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10281736 /UG=Hs.293678 hypothetical protein TCBAP0758 AF283769 mediator complex subunit 25 MED25 81857 NM_030973 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0035563 // positive regulation of chromatin binding // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 2001178 // positive regulation of mediator complex assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0046965 // retinoid X receptor binding // inferred from physical interaction 215898_at AK021879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021879.1 /DEF=Homo sapiens cDNA FLJ11817 fis, clone HEMBA1006421. /FEA=mRNA /DB_XREF=gi:10433165 /UG=Hs.293919 Homo sapiens cDNA FLJ11817 fis, clone HEMBA1006421 AK021879 tubulin tyrosine ligase-like family, member 5 TTLL5 23093 NM_015072 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 215899_at AK022331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022331.1 /DEF=Homo sapiens cDNA FLJ12269 fis, clone MAMMA1001635. /FEA=mRNA /DB_XREF=gi:10433706 /UG=Hs.293925 Homo sapiens cDNA FLJ12269 fis, clone MAMMA1001635 AK022331 215900_at AK022331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022331.1 /DEF=Homo sapiens cDNA FLJ12269 fis, clone MAMMA1001635. /FEA=mRNA /DB_XREF=gi:10433706 /UG=Hs.293925 Homo sapiens cDNA FLJ12269 fis, clone MAMMA1001635 AK022331 215901_at X68011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68011 /DEF=H.sapiens ZNF81 gene /FEA=CDS /DB_XREF=gi:454324 /UG=Hs.104020 zinc finger protein 81 (HFZ20) X68011 zinc finger protein 81 ZNF81 347344 NM_007137 /// XM_005272600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 215902_at AF009267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009267.1 /DEF=Homo sapiens clone FBA1 Cri-du-chat region mRNA. /FEA=mRNA /DB_XREF=gi:2331069 /UG=Hs.102238 Homo sapiens clone FBA1 Cri-du-chat region mRNA AF009267 215903_s_at BE786598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE786598 /FEA=EST /DB_XREF=gi:10207796 /DB_XREF=est:601478824F1 /CLONE=IMAGE:3881717 /UG=Hs.101474 KIAA0807 protein BE786598 microtubule associated serine/threonine kinase 2 MAST2 23139 NM_015112 /// XM_005270652 /// XM_005270653 /// XM_005270654 /// XM_005270655 /// XM_005270656 /// XM_005270659 /// XM_006710475 /// XM_006710476 /// XM_006710477 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045075 // regulation of interleukin-12 biosynthetic process // inferred from sequence or structural similarity /// 0048515 // spermatid differentiation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215904_at AL049698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049698 /DEF=Human DNA sequence from clone RP3-470B24 on chromosome 6q26-27. Contains the 3 end of the MLLT4 gene for myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) 4 (AF-6), ESTs and STSs /FEA=CDS_2 /DB_XREF=gi:6143632 /UG=Hs.100469 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 AL049698 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 MLLT4 4301 NM_001040000 /// NM_001040001 /// NM_001207008 /// NM_001291964 /// NM_005936 /// XM_005266996 /// XM_005266997 /// XM_006715483 /// XM_006715484 /// XM_006715485 /// XM_006715486 /// XM_006715487 /// XM_006715488 /// XM_006715489 /// XM_006715490 /// XM_006715491 /// XM_006715492 /// XM_006715493 /// XM_006715494 /// XR_427971 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 215905_s_at AL157420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157420.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D199 (from clone DKFZp434D199); partial cds. /FEA=mRNA /GEN=DKFZp434D199 /PROD=hypothetical protein /DB_XREF=gi:7018441 /UG=Hs.10290 U5 snRNP-specific 40 kDa protein (hPrp8-binding) AL157420 small nuclear ribonucleoprotein 40kDa (U5) SNRNP40 9410 NM_004814 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215906_at S65921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S65921.1 /DEF=anti-colorectal carcinoma light chain=glycoprotein CANAG-50 specific IgG1 kappa human, 19.9 hybridoma, antibody 1116NS19.9, mRNA, 998 nt. /FEA=mRNA /GEN=anti-colorectal carcinoma light chain /PROD=anti-colorectal carcinoma light chain /DB_XREF=gi:425519 /UG=Hs.103996 Anti-colorectal carcinoma light chain S65921 immunoglobulin kappa chain complex Igk 243469 0030183 // B cell differentiation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215907_at AK027193 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027193.1 /DEF=Homo sapiens cDNA: FLJ23540 fis, clone LNG08239. /FEA=mRNA /DB_XREF=gi:10440262 /UG=Hs.293931 Homo sapiens cDNA: FLJ23540 fis, clone LNG08239 AK027193 215908_at AF009267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009267.1 /DEF=Homo sapiens clone FBA1 Cri-du-chat region mRNA. /FEA=mRNA /DB_XREF=gi:2331069 /UG=Hs.102238 Homo sapiens clone FBA1 Cri-du-chat region mRNA AF009267 215909_x_at AL157418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157418.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761K18121 (from clone DKFZp761K18121). /FEA=mRNA /DB_XREF=gi:7018439 /UG=Hs.112028 MisshapenNIK-related kinase AL157418 misshapen-like kinase 1 MINK1 50488 NM_001024937 /// NM_015716 /// NM_153827 /// NM_170663 /// XM_005256664 /// XM_005256665 /// XM_005256666 /// XM_006721530 /// XM_006721531 /// XM_006721532 /// XM_006721533 /// XM_006721534 /// XM_006721535 /// XM_006721536 /// XM_006721537 /// XM_006721538 0001952 // regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0007254 // JNK cascade // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // inferred from mutant phenotype /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 215910_s_at AL137000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137000 /DEF=Human DNA sequence from clone RP11-203I16 on chromosome 13 Contains the gene for KIAA0970 protein, COX7CP1 (cytochrome c oxidase subunit VIIc pseudogene 1), a novel pseudogene, the GPR38 (G protein-coupled receptor 38) gene, ESTs, STSs, GSSs and a... /FEA=CDS_2 /DB_XREF=gi:9944121 /UG=Hs.103329 KIAA0970 protein AL137000 fibronectin type III domain containing 3A FNDC3A 22862 NM_001079673 /// NM_001278438 /// NM_014923 /// NR_103528 /// XM_006719777 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215911_x_at AW615612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW615612 /FEA=EST /DB_XREF=gi:7316310 /DB_XREF=est:ba12g08.x1 /CLONE=IMAGE:2824190 /UG=Hs.103124 ATPase, Ca++ transporting, plasma membrane 3 AW615612 ATPase, Ca++ transporting, plasma membrane 3 ATP2B3 492 NM_001001344 /// NM_021949 /// XM_005274689 /// XM_005274690 /// XM_005274691 /// XM_005274692 /// XM_005274693 /// XM_006724823 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215912_at AA758795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA758795 /FEA=EST /DB_XREF=gi:2806658 /DB_XREF=est:ah76a06.s1 /CLONE=1321522 /UG=Hs.296184 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O AA758795 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GNAO1 2775 NM_020988 /// NM_138736 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007212 // dopamine receptor signaling pathway // not recorded /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // inferred from electronic annotation 215913_s_at AK023668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023668.1 /DEF=Homo sapiens cDNA FLJ13606 fis, clone PLACE1010579, highly similar to Homo sapiens CED-6 protein (CED-6) mRNA. /FEA=mRNA /DB_XREF=gi:10435660 /UG=Hs.107056 CED-6 protein AK023668 GULP, engulfment adaptor PTB domain containing 1 GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 215914_at AK000864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000864.1 /DEF=Homo sapiens cDNA FLJ10002 fis, clone HEMBA1000046. /FEA=mRNA /DB_XREF=gi:7021188 /UG=Hs.296522 Homo sapiens cDNA FLJ10002 fis, clone HEMBA1000046 AK000864 215915_at AK023668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023668.1 /DEF=Homo sapiens cDNA FLJ13606 fis, clone PLACE1010579, highly similar to Homo sapiens CED-6 protein (CED-6) mRNA. /FEA=mRNA /DB_XREF=gi:10435660 /UG=Hs.107056 CED-6 protein AK023668 GULP, engulfment adaptor PTB domain containing 1 GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement 215916_at AL157418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157418.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761K18121 (from clone DKFZp761K18121). /FEA=mRNA /DB_XREF=gi:7018439 /UG=Hs.112028 MisshapenNIK-related kinase AL157418 cholinergic receptor, nicotinic, epsilon (muscle) CHRNE 1145 NM_000080 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0008324 // cation transmembrane transporter activity // traceable author statement /// 0015464 // acetylcholine receptor activity // traceable author statement 215917_at AL049037 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049037 /FEA=EST /DB_XREF=gi:4728346 /DB_XREF=est:DKFZp434P1518_r1 /CLONE=DKFZp434P1518 /UG=Hs.323833 syntaphilin AL049037 RAD21-like 1 (S. pombe) RAD21L1 642636 NM_001136566 /// XM_006723602 /// XM_006723603 /// XM_006723604 /// XM_006723605 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007128 // meiotic prophase I // inferred from sequence or structural similarity /// 0007129 // synapsis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030999 // linear element assembly // inferred from electronic annotation /// 0070197 // attachment of telomeric heterochromatin to nuclear envelope // inferred from electronic annotation /// 0072520 // seminiferous tubule development // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0030893 // meiotic cohesin complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 215918_s_at AA131826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA131826 /FEA=EST /DB_XREF=gi:1693379 /DB_XREF=est:zl37f06.s1 /CLONE=IMAGE:504131 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 AA131826 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215919_s_at BC000200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000200.1 /DEF=Homo sapiens, clone IMAGE:3352526, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3352526) /DB_XREF=gi:12652888 /UG=Hs.111286 hypothetical protein FLJ22512 BC000200 mitochondrial ribosomal protein S11 MRPS11 64963 NM_022839 /// NM_176805 /// XM_005254977 /// XM_005254978 0006412 // translation // inferred from electronic annotation /// 0042769 // DNA damage response, detection of DNA damage // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 215920_s_at AC002544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002544 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-761H5 /FEA=mRNA_3 /DB_XREF=gi:3337382 /UG=Hs.110613 KIAA0220 protein AC002544 nuclear pore complex interacting protein family, member A1 /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member B15 /// nuclear pore complex interacting protein family, member B3 /// nuclear pore complex interacting protein family, member B6 /// pyridoxal-dependent decarboxylase domain containing 2, pseudogene NPIPA1 /// NPIPA5 /// NPIPB15 /// NPIPB3 /// NPIPB6 /// PDXDC2P 9284 /// 23117 /// 283970 /// 440348 /// 728741 /// 100288332 NM_001018059 /// NM_001277325 /// NM_001282524 /// NM_006985 /// NM_130464 /// NM_199134 /// NR_003610 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005255694 /// XM_005255695 /// XM_005255741 /// XM_005255742 /// XM_005255743 /// XM_005256273 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006720979 /// XM_006720980 /// XM_006721079 /// XM_006721080 /// XM_006721081 /// XM_006721082 /// XM_006721083 /// XM_006721357 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006726636 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 215921_at AC002544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002544 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-761H5 /FEA=mRNA_3 /DB_XREF=gi:3337382 /UG=Hs.110613 KIAA0220 protein AC002544 nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member B3 /// nuclear pore complex interacting protein family, member B6 /// nuclear pore complex interacting protein family, member B8 NPIPA5 /// NPIPB3 /// NPIPB6 /// NPIPB8 23117 /// 728734 /// 728741 /// 100288332 NM_001277325 /// NM_001282524 /// NM_130464 /// XM_001132754 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005255741 /// XM_005255742 /// XM_005255743 /// XM_005255749 /// XM_005255750 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006721079 /// XM_006721080 /// XM_006721081 /// XM_006721082 /// XM_006721083 /// XM_006721111 /// XM_006721112 /// XM_006721113 /// XM_006721114 /// XM_006721115 /// XM_006721116 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006726616 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215922_at AL049259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049259.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E193 (from clone DKFZp564E193). /FEA=mRNA /DB_XREF=gi:4500005 /UG=Hs.11056 Homo sapiens mRNA; cDNA DKFZp564E193 (from clone DKFZp564E193) AL049259 RALBP1 associated Eps domain containing 1 REPS1 85021 NM_001128617 /// NM_001286611 /// NM_001286612 /// NM_031922 /// XM_005267177 /// XM_005267178 /// XM_005267179 /// XM_006715587 /// XR_245555 0006898 // receptor-mediated endocytosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 215923_s_at AK023421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023421.1 /DEF=Homo sapiens cDNA FLJ13359 fis, clone PLACE1000081, highly similar to Human SEC7 homolog Tic (TIC) mRNA. /FEA=mRNA /DB_XREF=gi:10435353 /UG=Hs.110121 SEC7 homolog AK023421 pleckstrin and Sec7 domain containing 4 PSD4 23550 NM_012455 /// XM_005263634 /// XM_006712392 /// XM_006712393 /// XM_006712394 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 215924_at AK022102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022102.1 /DEF=Homo sapiens cDNA FLJ12040 fis, clone HEMBB1001944. /FEA=mRNA /DB_XREF=gi:10433423 /UG=Hs.296687 Homo sapiens cDNA FLJ12040 fis, clone HEMBB1001944 AK022102 215925_s_at AF283777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF283777.2 /DEF=Homo sapiens clone TCBAP0702 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10281735 /UG=Hs.116481 CD72 antigen AF283777 CD72 molecule CD72 971 NM_001782 /// XM_005251632 /// XM_006716893 /// XM_006716894 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 215926_x_at AK023513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023513.1 /DEF=Homo sapiens cDNA FLJ13451 fis, clone PLACE1003030, weakly similar to Homo sapiens snRNA activating protein complex 190kD subunit (SNAP190) mRNA. /FEA=mRNA /DB_XREF=gi:10435468 /UG=Hs.113265 small nuclear RNA activating complex, polypeptide 4, 190kD AK023513 small nuclear RNA activating complex, polypeptide 4, 190kDa SNAPC4 6621 NM_003086 /// XM_005266096 /// XM_006717241 /// XM_006717242 /// XM_006717243 /// XM_006717244 /// XR_428535 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042795 // snRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0042796 // snRNA transcription from RNA polymerase III promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // traceable author statement /// 0019185 // snRNA-activating protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 215927_at AV657604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV657604 /FEA=EST /DB_XREF=gi:9878618 /DB_XREF=est:AV657604 /CLONE=GLCFDF06 /UG=Hs.118249 brefeldin A-inhibited guanine nucleotide-exchange protein 2 AV657604 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) ARFGEF2 10564 NM_006420 /// XM_005260252 /// XM_006723683 0001881 // receptor recycling // inferred from direct assay /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from mutant phenotype /// 0007032 // endosome organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005879 // axonemal microtubule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0032279 // asymmetric synapse // inferred from sequence or structural similarity /// 0032280 // symmetric synapse // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 215928_at AK022192 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022192.1 /DEF=Homo sapiens cDNA FLJ12130 fis, clone MAMMA1000251. /FEA=mRNA /DB_XREF=gi:10433534 /UG=Hs.319567 Homo sapiens cDNA FLJ12130 fis, clone MAMMA1000251 AK022192 215929_at AL080132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080132.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F083 (from clone DKFZp434F083). /FEA=mRNA /DB_XREF=gi:5262572 /UG=Hs.119207 Homo sapiens mRNA; cDNA DKFZp434F083 (from clone DKFZp434F083) AL080132 long intergenic non-protein coding RNA 837 LINC00837 100507605 NR_038374 /// NR_038375 /// NR_038376 215930_s_at U73682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U73682.1 /DEF=Human meningioma-expressed antigen 11 (MEA11) mRNA, partial cds. /FEA=mRNA /GEN=MEA11 /PROD=meningioma-expressed antigen 11 /DB_XREF=gi:1916671 /UG=Hs.117242 meningioma expressed antigen 6 (coiled-coil proline-rich) U73682 CTAGE family, member 5 CTAGE5 4253 NM_001247988 /// NM_001247989 /// NM_001247990 /// NM_005930 /// NM_203354 /// NM_203355 /// NM_203356 /// NM_203357 /// XM_005267646 /// XM_005267647 /// XM_005267648 /// XM_005267649 /// XM_005267650 /// XM_006720148 0043085 // positive regulation of catalytic activity // traceable author statement 0016020 // membrane // inferred from direct assay 0008047 // enzyme activator activity // traceable author statement 215931_s_at AV657604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV657604 /FEA=EST /DB_XREF=gi:9878618 /DB_XREF=est:AV657604 /CLONE=GLCFDF06 /UG=Hs.118249 brefeldin A-inhibited guanine nucleotide-exchange protein 2 AV657604 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) ARFGEF2 10564 NM_006420 /// XM_005260252 /// XM_006723683 0001881 // receptor recycling // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from mutant phenotype /// 0007032 // endosome organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005879 // axonemal microtubule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0032279 // asymmetric synapse // inferred from sequence or structural similarity /// 0032280 // symmetric synapse // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 215932_at AL031073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031073 /DEF=Human DNA sequence from clone 142F18 on chromosome Xq26.3-27.2 Contains part of a gene similar to melanoma-associated antigen, EST, GSS and an inverted repeat /FEA=CDS /DB_XREF=gi:4090213 /UG=Hs.123536 melanoma antigen, family E, 1, cancertestis specific AL031073 melanoma antigen family C, 2 MAGEC2 51438 NM_016249 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 215933_s_at Z21533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z21533.1 /DEF=H.sapiens HEX gene encoding homeobox related protein. /FEA=mRNA /GEN=HEX /PROD=homeobox related protein /DB_XREF=gi:32068 /UG=Hs.118651 hematopoietically expressed homeobox Z21533 hematopoietically expressed homeobox HHEX 3087 NM_002729 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0007049 // cell cycle // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010621 // negative regulation of transcription by transcription factor localization // inferred by curator /// 0010944 // negative regulation of transcription by competitive promoter binding // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred by curator /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0031016 // pancreas development // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0060431 // primary lung bud formation // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061010 // gall bladder development // inferred from electronic annotation /// 0061011 // hepatic duct development // inferred from electronic annotation /// 0061017 // hepatoblast differentiation // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0071103 // DNA conformation change // inferred from direct assay /// 0090009 // primitive streak formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0017025 // TBP-class protein binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // traceable author statement /// 0070491 // repressing transcription factor binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 215934_at D16471 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D16471.1 /DEF=Human mRNA, Xq terminal portion. /FEA=mRNA /DB_XREF=gi:495099 /UG=Hs.121571 Human mRNA, Xq terminal portion D16471 215935_at AL080148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080148.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B204 (from clone DKFZp434B204); partial cds. /FEA=mRNA /GEN=DKFZp434B204 /PROD=hypothetical protein /DB_XREF=gi:5262600 /UG=Hs.123004 DKFZP434B204 protein AL080148 SPATA31 subfamily A, member 1 /// SPATA31 subfamily A, member 3 /// SPATA31 subfamily A, member 5 /// SPATA31 subfamily A, member 6 /// SPATA31 subfamily A, member 7 SPATA31A1 /// SPATA31A3 /// SPATA31A5 /// SPATA31A6 /// SPATA31A7 26165 /// 389730 /// 647060 /// 727830 /// 727905 NM_001040065 /// NM_001083124 /// NM_001085452 /// NM_001113541 /// NM_001145196 /// NM_015667 /// XM_005272517 /// XM_006716851 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 215936_s_at AK001657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001657.1 /DEF=Homo sapiens cDNA FLJ10795 fis, clone NT2RP4000638. /FEA=mRNA /DB_XREF=gi:7023048 /UG=Hs.12144 KIAA1033 protein AK001657 KIAA1033 KIAA1033 23325 NM_001293640 /// NM_015275 /// XM_005268742 /// XM_005268743 /// XM_005268744 /// XM_005268745 /// XM_005268746 /// XR_245916 0016197 // endosomal transport // inferred from mutant phenotype /// 0016197 // endosomal transport // inferred from sequence or structural similarity 0005768 // endosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 215937_at U31099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U31099.1 /DEF=Human DP prostanoid receptor (PTGDR) mRNA, partial cds. /FEA=mRNA /GEN=PTGDR /PROD=DP prostanoid receptor /DB_XREF=gi:940376 /UG=Hs.158326 prostaglandin D2 receptor (DP) U31099 prostaglandin D2 receptor (DP) PTGDR 5729 NM_000953 /// NM_001281469 /// XM_005267891 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0030238 // male sex determination // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001785 // prostaglandin J receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004956 // prostaglandin D receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 215938_s_at AK001290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001290.1 /DEF=Homo sapiens cDNA FLJ10428 fis, clone NT2RP1000376, highly similar to Homo sapiens mRNA; cDNA DKFZp434A102. /FEA=mRNA /DB_XREF=gi:7022453 /UG=Hs.120360 phospholipase A2, group VI (cytosolic, calcium-independent) AK001290 phospholipase A2, group VI (cytosolic, calcium-independent) PLA2G6 8398 NM_001004426 /// NM_001199562 /// NM_003560 /// XM_005261764 /// XM_005261765 /// XM_005261766 /// XM_005261771 /// XM_006724332 /// XR_244390 /// XR_244392 /// XR_430411 /// XR_430412 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0090037 // positive regulation of protein kinase C signaling // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090238 // positive regulation of arachidonic acid secretion // inferred from electronic annotation /// 1901339 // regulation of store-operated calcium channel activity // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from electronic annotation 215939_at AU148005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148005 /FEA=EST /DB_XREF=gi:11009526 /DB_XREF=est:AU148005 /CLONE=MAMMA1002355 /UG=Hs.296718 Homo sapiens cDNA FLJ12359 fis, clone MAMMA1002355 AU148005 215940_at U80773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80773.1 /DEF=Human EST clone 42944 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2231376 /UG=Hs.121580 Human EST clone 42944 mariner transposon Hsmar1 sequence U80773 long intergenic non-protein coding RNA 1361 LINC01361 101927498 NR_110632 /// NR_110633 /// XR_246352 /// XR_246353 /// XR_248783 /// XR_248784 /// XR_250769 /// XR_250770 215941_at D16471 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D16471.1 /DEF=Human mRNA, Xq terminal portion. /FEA=mRNA /DB_XREF=gi:495099 /UG=Hs.121571 Human mRNA, Xq terminal portion D16471 215942_s_at BF973178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF973178 /FEA=EST /DB_XREF=gi:12340304 /DB_XREF=est:602241428F1 /CLONE=IMAGE:4330015 /UG=Hs.122552 G-2 and S-phase expressed 1 BF973178 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 215943_at AB051448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051448.1 /DEF=Homo sapiens mRNA for KIAA1661 protein, partial cds. /FEA=mRNA /GEN=KIAA1661 /PROD=KIAA1661 protein /DB_XREF=gi:13359194 /UG=Hs.122309 Homo sapiens mRNA for KIAA1661 protein, partial cds AB051448 KIAA1661 protein KIAA1661 85375 215944_at U80773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80773.1 /DEF=Human EST clone 42944 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2231376 /UG=Hs.121580 Human EST clone 42944 mariner transposon Hsmar1 sequence U80773 long intergenic non-protein coding RNA 1361 LINC01361 101927498 NR_110632 /// NR_110633 /// XR_246352 /// XR_246353 /// XR_248783 /// XR_248784 /// XR_250769 /// XR_250770 215945_s_at BC005016 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005016.1 /DEF=Homo sapiens, clone IMAGE:3636175, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3636175) /DB_XREF=gi:13477122 /UG=Hs.12372 tripartite motif protein TRIM2 BC005016 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215946_x_at AL022324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022324 /DEF=Human DNA sequence from clone CTA-246H3 on chromosome 22 Contains the gene for IGLL1 (immunoglobulin lambda-like polypeptide 1, pre-B-cell specific), a pseudogene similar to LRP5 (Lipoprotein Receptor Related Protein.), ESTs, Genomic markers (D22S... /FEA=mRNA /DB_XREF=gi:3702433 /UG=Hs.296552 immunoglobulin lambda-like polypeptide 3 AL022324 immunoglobulin lambda-like polypeptide 3, pseudogene IGLL3P 91353 NM_001013618 /// NR_029395 215947_s_at AF090094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090094.1 /DEF=Homo sapiens clone IMAGE 172979. /FEA=mRNA /DB_XREF=gi:4063629 /UG=Hs.125078 ornithine decarboxylase antizyme 1 AF090094 family with sequence similarity 136, member A /// protein FAM136A-like FAM136A /// LOC100287852 84908 /// 100287852 NM_032822 /// XM_002342390 /// XM_003119906 /// XM_003960331 /// XM_005264620 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 215948_x_at AI522311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI522311 /FEA=EST /DB_XREF=gi:4436446 /DB_XREF=est:ti76f07.x1 /CLONE=IMAGE:2137957 /UG=Hs.124386 zinc finger protein 237 AI522311 zinc finger, MYM-type 5 ZMYM5 9205 NM_001039649 /// NM_001039650 /// NM_001142684 /// NM_014242 /// XM_005266593 /// XM_005266594 /// XM_005266595 /// XM_006719894 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215949_x_at BF002659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF002659 /FEA=EST /DB_XREF=gi:10702934 /DB_XREF=est:7h12e01.x1 /CLONE=IMAGE:3315768 /UG=Hs.1349 colony stimulating factor 2 (granulocyte-macrophage) BF002659 immunoglobulin heavy constant mu IGHM 3507 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 215951_at AL137303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137303.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434O086 (from clone DKFZp434O086). /FEA=mRNA /DB_XREF=gi:6807767 /UG=Hs.126084 KIAA1055 protein AL137303 RP11-114H24.6 215952_s_at AF090094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090094.1 /DEF=Homo sapiens clone IMAGE 172979. /FEA=mRNA /DB_XREF=gi:4063629 /UG=Hs.125078 ornithine decarboxylase antizyme 1 AF090094 ornithine decarboxylase antizyme 1 OAZ1 4946 NM_004152 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 215953_at AL050020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050020.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C196 (from clone DKFZp564C196); partial cds. /FEA=mRNA /GEN=DKFZp564C196 /PROD=hypothetical protein /DB_XREF=gi:4884089 /UG=Hs.127384 DKFZP564C196 protein AL050020 SMG7 antisense RNA 1 SMG7-AS1 284649 NR_040063 215954_s_at AI200896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI200896 /FEA=EST /DB_XREF=gi:3753502 /DB_XREF=est:qf68d05.x1 /CLONE=IMAGE:1755177 /UG=Hs.128425 NY-REN-24 antigen AI200896 cactin, spliceosome C complex subunit CACTIN 58509 NM_001080543 /// NM_021231 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 215955_x_at Y10388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y10388 /DEF=H.sapiens graf gene /FEA=CDS /DB_XREF=gi:7340768 /UG=Hs.132942 GTPase regulator associated with the focal adhesion kinase pp125(FAK); KIAA0621 protein Y10388 Rho GTPase activating protein 26 ARHGAP26 23092 NM_001135608 /// NM_015071 /// XM_005268398 /// XM_005268399 /// XM_005268400 /// XM_005268402 /// XM_005268403 /// XM_006714768 /// XM_006714769 /// XM_006714770 /// XM_006714771 /// XM_006714772 /// XM_006714773 /// XM_006714774 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 215956_at AK022065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022065.1 /DEF=Homo sapiens cDNA FLJ12003 fis, clone HEMBB1001537. /FEA=mRNA /DB_XREF=gi:10433385 /UG=Hs.296683 Homo sapiens cDNA FLJ12003 fis, clone HEMBB1001537 AK022065 215957_at AV731367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV731367 /FEA=EST /DB_XREF=gi:10840788 /DB_XREF=est:AV731367 /CLONE=HTFABG11 /UG=Hs.129683 Homo sapiens unknown mRNA, sequence AV731367 ubiquitin-conjugating enzyme E2D 1 UBE2D1 7321 NM_001204880 /// NM_003338 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 215958_at AK022065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022065.1 /DEF=Homo sapiens cDNA FLJ12003 fis, clone HEMBB1001537. /FEA=mRNA /DB_XREF=gi:10433385 /UG=Hs.296683 Homo sapiens cDNA FLJ12003 fis, clone HEMBB1001537 AK022065 215959_at AK001131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001131.1 /DEF=Homo sapiens cDNA FLJ10269 fis, clone HEMBB1001068, highly similar to Homo sapiens liprin-beta2 mRNA. /FEA=mRNA /DB_XREF=gi:7022198 /UG=Hs.12953 PTPRF interacting protein, binding protein 2 (liprin beta 2) AK001131 215960_at AJ133127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ133127.1 /DEF=Homo sapiens mRNA for sodium-glucose cotransporter (SGLT2 gene). /FEA=mRNA /GEN=SGLT2 /PROD=sodium-glucose cotransporter /DB_XREF=gi:7263937 /UG=Hs.130101 solute carrier family 5 (neutral amino acid transporters, system A), member 4 AJ133127 solute carrier family 5 (glucose activated ion channel), member 4 SLC5A4 6527 NM_014227 /// XM_006724308 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 215961_at BF530348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF530348 /FEA=EST /DB_XREF=gi:11617711 /DB_XREF=est:602071648F1 /CLONE=IMAGE:4214651 /UG=Hs.1321 coagulation factor XII (Hageman factor) BF530348 coagulation factor XII (Hageman factor) F12 2161 NM_000505 0002353 // plasma kallikrein-kinin cascade // inferred from direct assay /// 0002542 // Factor XII activation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // inferred by curator /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010756 // positive regulation of plasminogen activation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016540 // protein autoprocessing // inferred from direct assay /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0031638 // zymogen activation // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051788 // response to misfolded protein // inferred from direct assay /// 0051919 // positive regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051787 // misfolded protein binding // inferred by curator /// 0070009 // serine-type aminopeptidase activity // inferred from electronic annotation 215962_at F10112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:F10112 /FEA=EST /DB_XREF=gi:682615 /DB_XREF=est:HSC3AG012 /CLONE=c-3ag01 /UG=Hs.13252 Human EST clone 22453 mariner transposon Hsmar1 sequence F10112 215963_x_at Z98200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98200 /DEF=Human DNA sequence from clone RP1-111B22 on chromosome 6q16-21 Contains a novel pseudogene, a pseudogene similar to ribosomal protein L3, ESTs, STSs, GSSs and CpG Islands /FEA=CDS_1 /DB_XREF=gi:6002294 /UG=Hs.296559 Human DNA sequence from clone RP1-111B22 on chromosome 6q16-21 Contains a novel pseudogene, a pseudogene similar to ribosomal protein L3, ESTs, STSs, GSSs and CpG Islands Z98200 ribosomal protein L3 RPL3 6122 NM_000967 /// NM_001033853 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 215964_at U80766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80766.1 /DEF=Human EST clone 22453 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2231369 /UG=Hs.13252 Human EST clone 22453 mariner transposon Hsmar1 sequence U80766 215965_at AK022421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022421.1 /DEF=Homo sapiens cDNA FLJ12359 fis, clone MAMMA1002355. /FEA=mRNA /DB_XREF=gi:10433814 /UG=Hs.296718 Homo sapiens cDNA FLJ12359 fis, clone MAMMA1002355 AK022421 215966_x_at AA292874 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA292874 /FEA=EST /DB_XREF=gi:1941855 /DB_XREF=est:zt66a07.r1 /CLONE=IMAGE:727284 /UG=Hs.1466 glycerol kinase AA292874 glycerol kinase 3 pseudogene GK3P 2713 NR_026575 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019563 // glycerol catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // inferred from electronic annotation /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 215967_s_at AL582804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL582804 /FEA=EST /DB_XREF=gi:12951151 /DB_XREF=est:AL582804 /CLONE=CS0DL011YC18 (3 prime) /UG=Hs.153042 lymphocyte antigen 9 AL582804 lymphocyte antigen 9 LY9 4063 NM_001033667 /// NM_001261456 /// NM_001261457 /// NM_002348 /// XM_005245164 /// XM_006711320 /// XM_006711321 /// XM_006711322 /// XM_006711323 /// XM_006711324 /// XM_006711325 0007155 // cell adhesion // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 215968_at AF055018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055018.1 /DEF=Homo sapiens clone 24442 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005745 /UG=Hs.139137 Homo sapiens clone 24442 mRNA sequence AF055018 215969_at AL079289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079289.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35971. /FEA=mRNA /DB_XREF=gi:5102748 /UG=Hs.137154 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35971 AL079289 215970_at AL122093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122093.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B2115 (from clone DKFZp434B2115). /FEA=mRNA /DB_XREF=gi:6102904 /UG=Hs.136241 Homo sapiens mRNA; cDNA DKFZp434B2115 (from clone DKFZp434B2115) AL122093 POTE ankyrin domain family, member F pseudogene LOC100130331 100130331 NR_027247 215971_at AK022120 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022120.1 /DEF=Homo sapiens cDNA FLJ12058 fis, clone HEMBB1002092. /FEA=mRNA /DB_XREF=gi:10433445 /UG=Hs.296688 Homo sapiens cDNA FLJ12058 fis, clone HEMBB1002092 AK022120 215972_at AF070547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070547.1 /DEF=Homo sapiens clone 24820 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387909 /UG=Hs.146312 Homo sapiens clone 24820 mRNA sequence AF070547 prostate androgen-regulated transcript 1 (non-protein coding) PART1 25859 NM_001039499 /// NM_001040639 /// NR_024617 /// NR_028508 /// NR_028509 215973_at AF036973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF036973 /FEA=EST /DB_XREF=gi:4104610 /DB_XREF=est:AF036973 /CLONE=HCG IV.5 /UG=Hs.145477 HCGIV-6 protein AF036973 HLA complex group 4B (non-protein coding) HCG4B 80868 NR_001317 215974_at AF036973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF036973 /FEA=EST /DB_XREF=gi:4104610 /DB_XREF=est:AF036973 /CLONE=HCG IV.5 /UG=Hs.145477 HCGIV-6 protein AF036973 215975_x_at X68285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68285.1 /DEF=H.sapiens mRNA for glycerol kinase. /FEA=mRNA /PROD=glycerol kinase /DB_XREF=gi:38413 /UG=Hs.1466 glycerol kinase X68285 GK antisense RNA 1 /// GK-AS1 /// GK-AS1 215976_at AU146945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146945 /FEA=EST /DB_XREF=gi:11008466 /DB_XREF=est:AU146945 /CLONE=HEMBB1001944 /UG=Hs.296687 Homo sapiens cDNA FLJ12040 fis, clone HEMBB1001944 AU146945 215977_x_at X68285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68285.1 /DEF=H.sapiens mRNA for glycerol kinase. /FEA=mRNA /PROD=glycerol kinase /DB_XREF=gi:38413 /UG=Hs.1466 glycerol kinase X68285 glycerol kinase GK 2710 NM_000167 /// NM_001128127 /// NM_001205019 /// NM_203391 /// XM_005274488 /// XM_006724483 /// XM_006724484 /// XM_006724485 /// XM_006724486 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from mutant phenotype /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046167 // glycerol-3-phosphate biosynthetic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // inferred from mutant phenotype /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 215978_x_at AK021514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021514.1 /DEF=Homo sapiens cDNA FLJ11452 fis, clone HEMBA1001435. /FEA=mRNA /DB_XREF=gi:10432710 /UG=Hs.148598 Homo sapiens cDNA FLJ11452 fis, clone HEMBA1001435 AK021514 zinc finger protein 721 ZNF721 170960 NM_133474 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 215979_s_at AK022999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022999.1 /DEF=Homo sapiens cDNA FLJ12937 fis, clone NT2RP2005020. /FEA=mRNA /DB_XREF=gi:10434712 /UG=Hs.14846 Homo sapiens mRNA; cDNA DKFZp564D016 (from clone DKFZp564D016) AK022999 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 SLC7A1 6541 NM_003045 /// XM_005266507 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015809 // arginine transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015181 // arginine transmembrane transporter activity // inferred from electronic annotation 215980_s_at AF052128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052128.1 /DEF=Homo sapiens clone 23677 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360437 /UG=Hs.1521 immunoglobulin mu binding protein 2 AF052128 immunoglobulin mu binding protein 2 IGHMBP2 3508 NM_002180 /// XM_005273974 /// XM_005273975 /// XM_005273976 /// XM_005273977 /// XR_247198 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from sequence or structural similarity /// 0032797 // SMN complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // traceable author statement /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032575 // ATP-dependent 5'-3' RNA helicase activity // inferred from direct assay /// 0043022 // ribosome binding // inferred from direct assay /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215981_at AL137606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137606.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0211 (from clone DKFZp434H0211). /FEA=mRNA /DB_XREF=gi:6808354 /UG=Hs.151171 Homo sapiens mRNA; cDNA DKFZp434H0211 (from clone DKFZp434H0211) AL137606 uncharacterized LOC100505534 LOC100505534 100505534 XR_109178 /// XR_172078 /// XR_429516 /// XR_429517 /// XR_433083 /// XR_433084 215982_s_at AL049547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049547 /DEF=Human DNA sequence from clone RP1-34F7 on chromosome 6p21.2-21.33. Contains the 3 end of the gene for CREB-RP (G13), the gene for tenascin XB and XA, the CYP21A2 gene for cytochrome P450, subfamily XXIA (steroid 21-hydroxylase), polypeptide 2 (CY... /FEA=CDS_6 /DB_XREF=gi:7406725 /UG=Hs.153299 DOM-3 (C. elegans) homolog Z AL049547 decapping exoribonuclease DXO 1797 NM_005510 /// XM_006715005 /// XM_006715006 /// XM_006715007 /// XM_006725474 /// XM_006725475 /// XM_006725476 /// XM_006725688 /// XM_006725689 /// XM_006725690 /// XM_006725898 /// XM_006725899 /// XM_006725900 /// XM_006725985 /// XM_006725986 /// XM_006725987 /// XM_006726078 /// XM_006726079 /// XM_006726080 /// XR_427826 /// XR_430856 /// XR_430934 /// XR_430935 /// XR_430996 /// XR_431013 /// XR_431043 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0050779 // RNA destabilization // inferred from sequence or structural similarity /// 0071028 // nuclear mRNA surveillance // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008409 // 5'-3' exonuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034353 // RNA pyrophosphohydrolase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 215983_s_at D83768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D83768.1 /DEF=Human clone N9S Rep-8 mRNA, partial cds. /FEA=mRNA /GEN=Rep-8 /DB_XREF=gi:1913786 /UG=Hs.153678 reproduction 8 D83768 UBX domain protein 8 UBXN8 7993 NM_001282189 /// NM_001282199 /// NM_005671 0007338 // single fertilization // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 215984_s_at AL121845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121845 /DEF=Human DNA sequence from clone RP4-583P15 on chromosome 20 Contains ESTs, STSs, GSSs and ten CpG islands. Contains the TNFRSF6B gene for tumor necrosis factor receptor 6b (decoy), the 3 part of the KIAA1088 gene, the ARFRP1 gene for ADP-ribosylati... /FEA=mRNA_1 /DB_XREF=gi:8246778 /UG=Hs.307140 Human DNA sequence from clone RP4-583P15 on chromosome 20 Contains ESTs, STSs, GSSs and ten CpG islands. Contains the TNFRSF6B gene for tumor necrosis factor receptor 6b (decoy), the 3 part of the KIAA1088 gene, the ARFRP1 gene for ADP-ribosylation facto AL121845 ADP-ribosylation factor related protein 1 ARFRP1 10139 NM_001134758 /// NM_001267544 /// NM_001267545 /// NM_001267546 /// NM_001267547 /// NM_001267548 /// NM_001267549 /// NM_003224 /// NR_051954 /// NR_051955 /// NR_051956 /// NR_051957 /// NR_051958 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 215985_at X92110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X92110.1 /DEF=H.sapiens mRNA for hcgVIII protein. /FEA=mRNA /DB_XREF=gi:1216163 /UG=Hs.153618 HCGVIII-1 protein X92110 HLA complex group 8 /// ZNRD1 antisense RNA 1 HCG8 /// ZNRD1-AS1 80862 /// 100507399 NR_026751 /// NR_103542 215986_at AU146999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146999 /FEA=EST /DB_XREF=gi:11008520 /DB_XREF=est:AU146999 /CLONE=HEMBB1002092 /UG=Hs.296688 Homo sapiens cDNA FLJ12058 fis, clone HEMBB1002092 AU146999 215987_at AV654984 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV654984 /FEA=EST /DB_XREF=gi:9875998 /DB_XREF=est:AV654984 /CLONE=GLCEBE10 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 AV654984 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 215988_s_at AL121981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121981 /DEF=Human DNA sequence from clone RP5-1061C18 on chromosome 1p36.22-36.33. Contains ESTs, STSs, GSSs and a CpG island. Contains the 5 part of the DLG1 gene encoding the discs protein (large Drosophila homolog 1, presynaptic protein SAP97) with five i... /FEA=CDS_3 /DB_XREF=gi:9931107 /UG=Hs.154294 discs, large (Drosophila) homolog 1 AL121981 discs, large homolog 1 (Drosophila) DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 215989_at BE258133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE258133 /FEA=EST /DB_XREF=gi:9128618 /DB_XREF=est:601114754F1 /CLONE=IMAGE:3355524 /UG=Hs.307356 chromobox homolog 2 (Drosophila Pc class) BE258133 chromobox homolog 2 CBX2 84733 NM_005189 /// NM_032647 /// XM_006722140 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007548 // sex differentiation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045137 // development of primary sexual characteristics // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from electronic annotation 215990_s_at S67779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S67779.1 /DEF=BCL5=Cys2-His2 zinc-finger transcription factor human, liver, mRNA, 2600 nt. /FEA=mRNA /DB_XREF=gi:459372 /UG=Hs.155024 B-cell CLLlymphoma 6 (zinc finger protein 51) S67779 B-cell CLL/lymphoma 6 BCL6 604 NM_001130845 /// NM_001134738 /// NM_001706 /// NM_138931 /// XM_005247694 0000060 // protein import into nucleus, translocation // inferred from genetic interaction /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // non-traceable author statement /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032764 // negative regulation of mast cell cytokine production // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042092 // type 2 immune response // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043380 // regulation of memory T cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0048294 // negative regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 215991_s_at AU121504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU121504 /FEA=EST /DB_XREF=gi:10936739 /DB_XREF=est:AU121504 /CLONE=MAMMA1000296 /UG=Hs.154797 KIAA0090 protein AU121504 ER membrane protein complex subunit 1 EMC1 23065 NM_001271427 /// NM_001271428 /// NM_001271429 /// NM_015047 /// XM_005245787 /// XM_005245788 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 215992_s_at AL117397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117397.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586O1422 (from clone DKFZp586O1422); partial cds. /FEA=mRNA /GEN=DKFZp586O1422 /PROD=hypothetical protein /DB_XREF=gi:5911916 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 AL117397 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 215993_at AF070543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070543.1 /DEF=Homo sapiens clone 24740 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387903 /UG=Hs.155915 Homo sapiens clone 24740 mRNA sequence AF070543 215994_x_at AK001196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001196.1 /DEF=Homo sapiens cDNA FLJ10334 fis, clone NT2RM2000649, highly similar to Homo sapiens mRNA for KIAA0676 protein. /FEA=mRNA /DB_XREF=gi:7022298 /UG=Hs.155829 KIAA0676 protein AK001196 TBC1 domain family, member 9B (with GRAM domain) TBC1D9B 23061 NM_015043 /// NM_198868 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 215995_x_at AU147598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147598 /FEA=EST /DB_XREF=gi:11009119 /DB_XREF=est:AU147598 /CLONE=MAMMA1001143 /UG=Hs.296707 Homo sapiens cDNA FLJ12226 fis, clone MAMMA1001143 AU147598 215996_at AI446234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI446234 /FEA=EST /DB_XREF=gi:4293782 /DB_XREF=est:tj25g10.x1 /CLONE=IMAGE:2142594 /UG=Hs.156072 Human pre-TNK cell associated protein (1F6) mRNA, 3 end AI446234 215997_s_at AV694732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV694732 /FEA=EST /DB_XREF=gi:10296595 /DB_XREF=est:AV694732 /CLONE=GKCGZH06 /UG=Hs.155976 cullin 4B AV694732 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 215998_at R38712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R38712 /FEA=EST /DB_XREF=gi:796168 /DB_XREF=est:yd03b02.s1 /CLONE=IMAGE:24533 /UG=Hs.155959 Homo sapiens clone 24533 mRNA sequence R38712 215999_at U43383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U43383.1 /DEF=Human unidentified mRNA mapping to CMT1A-REP elements, partial cds. /FEA=mRNA /DB_XREF=gi:4204709 /UG=Hs.158313 chromosome 17 open reading frame 1A U43383 CMT1A duplicated region transcript 1 CDRT1 374286 NM_001282540 /// NM_006382 216000_at AA732995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA732995 /FEA=EST /DB_XREF=gi:2754354 /DB_XREF=est:zg74c03.s1 /CLONE=IMAGE:399076 /UG=Hs.158095 KIAA0484 protein AA732995 216001_at AL023753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023753 /DEF=Human DNA sequence from clone 1198H6 on chromosome 1p36.11-36.31. Contains two Melanoma Preferentially Expressed Antigen PRAME LIKE genes. Contains GSSs and ESTs /FEA=mRNA_2 /DB_XREF=gi:3702426 /UG=Hs.156406 Human DNA sequence from clone 1198H6 on chromosome 1p36.11-36.31. Contains two Melanoma Preferentially Expressed Antigen PRAME LIKE genes. Contains GSSs and ESTs AL023753 PRAME family member 12 PRAMEF12 390999 NM_001080830 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0042974 // retinoic acid receptor binding // inferred from electronic annotation 216002_at AU147200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147200 /FEA=EST /DB_XREF=gi:11008721 /DB_XREF=est:AU147200 /CLONE=HEMBB1002699 /UG=Hs.296698 Homo sapiens cDNA FLJ12105 fis, clone HEMBB1002699 AU147200 216003_at U43383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U43383.1 /DEF=Human unidentified mRNA mapping to CMT1A-REP elements, partial cds. /FEA=mRNA /DB_XREF=gi:4204709 /UG=Hs.158313 chromosome 17 open reading frame 1A U43383 AC005838.2 216004_s_at AP001748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AP001748 /DEF=Homo sapiens genomic DNA, chromosome 21q, section 92105 /FEA=mRNA_3 /DB_XREF=gi:7768745 /UG=Hs.158225 PBXknotted 1 homeobox 1 AP001748 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216005_at BF434846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF434846 /FEA=EST /DB_XREF=gi:11447134 /DB_XREF=est:7o74d07.x1 /CLONE=IMAGE:3641917 /UG=Hs.296757 Homo sapiens cDNA: FLJ20933 fis, clone ADSE01388 BF434846 tenascin C TNC 3371 NM_002160 /// XM_005251972 /// XM_005251973 /// XM_005251974 /// XM_005251975 /// XM_006717096 /// XM_006717097 /// XM_006717098 /// XM_006717099 /// XM_006717100 /// XM_006717101 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0060447 // bud outgrowth involved in lung branching // inferred from electronic annotation /// 0060739 // mesenchymal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0045545 // syndecan binding // inferred from physical interaction 216006_at AF070620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070620.1 /DEF=Homo sapiens clone 24694 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3283886 /UG=Hs.158530 Homo sapiens clone 24694 mRNA sequence AF070620 216007_at AF052176 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052176.1 /DEF=Homo sapiens clone 24457 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360487 /UG=Hs.158529 Homo sapiens clone 24457 mRNA sequence AF052176 216008_s_at AV694434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV694434 /FEA=EST /DB_XREF=gi:10296297 /DB_XREF=est:AV694434 /CLONE=GKCBIC10 /UG=Hs.241558 ariadne (Drosophila) homolog 2 AV694434 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216009_at U92027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U92027.1 /DEF=Human clone 61501 defective mariner transposon Hsmar2 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2052469 /UG=Hs.159211 Human clone 61501 defective mariner transposon Hsmar2 mRNA sequence U92027 solute carrier family 39, member 9 SLC39A9 55334 NM_001252148 /// NM_001252150 /// NM_001252151 /// NM_001252152 /// NM_018375 /// XM_005267834 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 216010_x_at D89324 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D89324 /DEF=Homo sapiens DNA for alpha (1,31,4) fucosyltransferase, complete cds /FEA=CDS /DB_XREF=gi:1694694 /UG=Hs.169238 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) D89324 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) FUT3 2525 NM_000149 /// NM_001097639 /// NM_001097640 /// NM_001097641 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009988 // cell-cell recognition // inferred by curator /// 0036065 // fucosylation // inferred from direct assay /// 0036065 // fucosylation // inferred from electronic annotation /// 0042355 // L-fucose catabolic process // non-traceable author statement /// 0043413 // macromolecule glycosylation // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008417 // fucosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017060 // 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // inferred from direct assay 216011_at U92027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U92027.1 /DEF=Human clone 61501 defective mariner transposon Hsmar2 mRNA sequence. /FEA=mRNA /DB_XREF=gi:2052469 /UG=Hs.159211 Human clone 61501 defective mariner transposon Hsmar2 mRNA sequence U92027 solute carrier family 39, member 9 SLC39A9 55334 NM_001252148 /// NM_001252150 /// NM_001252151 /// NM_001252152 /// NM_018375 /// XM_005267834 0006829 // zinc ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 216012_at U43604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U43604.1 /DEF=Human unidentified mRNA, partial sequence. /FEA=mRNA /DB_XREF=gi:1171236 /UG=Hs.159901 Human unidentified mRNA, partial sequence U43604 216013_at AL034396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034396 /DEF=Human DNA sequence from clone 1158B12 on chromosome Xp11.21-11.4 Contains the ZXDA gene for X-linked duplicated Zinc finger A, and MYCL1 (v-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived) and KRT8 (Keratin 8, Cytokerat... /FEA=mRNA /DB_XREF=gi:4902597 /UG=Hs.159249 zinc finger, X-linked, duplicated A AL034396 zinc finger, X-linked, duplicated B ZXDB 158586 NM_007157 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216014_s_at AL034396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034396 /DEF=Human DNA sequence from clone 1158B12 on chromosome Xp11.21-11.4 Contains the ZXDA gene for X-linked duplicated Zinc finger A, and MYCL1 (v-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived) and KRT8 (Keratin 8, Cytokerat... /FEA=mRNA /DB_XREF=gi:4902597 /UG=Hs.159249 zinc finger, X-linked, duplicated A AL034396 zinc finger, X-linked, duplicated A /// zinc finger, X-linked, duplicated B ZXDA /// ZXDB 7789 /// 158586 NM_007156 /// NM_007157 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 216015_s_at AK027194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027194.1 /DEF=Homo sapiens cDNA: FLJ23541 fis, clone LNG08276, highly similar to AF054176 Homo sapiens angiotensinvasopressin receptor AIIAVP mRNA. /FEA=mRNA /DB_XREF=gi:10440263 /UG=Hs.159483 chromosome 1 open reading frame 7 AK027194 NLR family, pyrin domain containing 3 NLRP3 114548 NM_001079821 /// NM_001127461 /// NM_001127462 /// NM_001243133 /// NM_004895 /// NM_183395 /// XM_005273036 /// XM_005273037 /// XM_005273038 /// XM_006711733 0002674 // negative regulation of acute inflammatory response // inferred from mutant phenotype /// 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0009595 // detection of biotic stimulus // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032621 // interleukin-18 production // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044546 // NLRP3 inflammasome complex assembly // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050701 // interleukin-1 secretion // inferred from electronic annotation /// 0050713 // negative regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051259 // protein oligomerization // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042834 // peptidoglycan binding // traceable author statement 216016_at AK027194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027194.1 /DEF=Homo sapiens cDNA: FLJ23541 fis, clone LNG08276, highly similar to AF054176 Homo sapiens angiotensinvasopressin receptor AIIAVP mRNA. /FEA=mRNA /DB_XREF=gi:10440263 /UG=Hs.159483 chromosome 1 open reading frame 7 AK027194 NLR family, pyrin domain containing 3 NLRP3 114548 NM_001079821 /// NM_001127461 /// NM_001127462 /// NM_001243133 /// NM_004895 /// NM_183395 /// XM_005273036 /// XM_005273037 /// XM_005273038 /// XM_006711733 0002674 // negative regulation of acute inflammatory response // inferred from mutant phenotype /// 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0009595 // detection of biotic stimulus // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032621 // interleukin-18 production // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044546 // NLRP3 inflammasome complex assembly // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050701 // interleukin-1 secretion // inferred from electronic annotation /// 0050713 // negative regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051259 // protein oligomerization // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042834 // peptidoglycan binding // traceable author statement 216017_s_at AJ011081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ011081 /DEF=Homo sapiens mader gene, partial /FEA=CDS /DB_XREF=gi:3646138 /UG=Hs.159223 NGFI-A binding protein 2 (ERG1 binding protein 2) AJ011081 NGFI-A binding protein 2 (EGR1 binding protein 2) NAB2 4665 NM_005967 /// XM_005268894 0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0016480 // negative regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation 216018_at AJ243936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ243936.1 /DEF=Homo sapiens mRNA for G16 protein (G16 gene located in the class III region of the major histocompatibility complex). /FEA=mRNA /GEN=G16 /PROD=protein G16 /DB_XREF=gi:5578772 /UG=Hs.226019 Homo sapiens mRNA for G16 protein (G16 gene located in the class III region of the major histocompatibility complex) AJ243936 ring finger protein 5, E3 ubiquitin protein ligase RNF5 6048 NM_006913 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216019_x_at AK021690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021690.1 /DEF=Homo sapiens cDNA FLJ11628 fis, clone HEMBA1004238. /FEA=mRNA /DB_XREF=gi:10432926 /UG=Hs.306610 Homo sapiens cDNA FLJ11628 fis, clone HEMBA1004238 AK021690 microRNA 6716 /// pleckstrin homology-like domain, family B, member 1 MIR6716 /// PHLDB1 23187 /// 102466719 NM_001144758 /// NM_001144759 /// NM_015157 /// NR_106773 /// XM_005271468 /// XM_005271469 /// XM_005271470 /// XM_005271471 /// XM_005271472 /// XM_005271473 /// XM_005271474 /// XM_005271475 /// XM_005271477 /// XM_005277680 /// XM_006718796 /// XM_006718797 /// XM_006718798 /// XM_006718799 /// XM_006718800 /// XM_006718801 /// XM_006718802 /// XM_006718803 /// XM_006718804 /// XR_428972 216020_at AL080107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080107.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586D0522 (from clone DKFZp586D0522). /FEA=mRNA /DB_XREF=gi:5262532 /UG=Hs.163173 Homo sapiens mRNA; cDNA DKFZp586D0522 (from clone DKFZp586D0522) AL080107 interferon induced with helicase C domain 1 IFIH1 64135 NM_022168 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009597 // detection of virus // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032727 // positive regulation of interferon-alpha production // inferred from mutant phenotype /// 0032727 // positive regulation of interferon-alpha production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034344 // regulation of type III interferon production // traceable author statement /// 0039528 // cytoplasmic pattern recognition receptor signaling pathway in response to virus // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216021_s_at AW298713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW298713 /FEA=EST /DB_XREF=gi:6705349 /DB_XREF=est:UI-H-BW0-ajo-f-12-0-UI.s1 /CLONE=IMAGE:2732686 /UG=Hs.167742 glycine receptor, alpha 3 AW298713 glycine receptor, alpha 3 GLRA3 8001 NM_001042543 /// NM_006529 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016935 // glycine-gated chloride channel complex // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // non-traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016934 // extracellular-glycine-gated chloride channel activity // inferred from electronic annotation /// 0022824 // transmitter-gated ion channel activity // inferred from electronic annotation /// 0030594 // neurotransmitter receptor activity // non-traceable author statement 216022_at AL049278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049278.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I153 (from clone DKFZp564I153). /FEA=mRNA /DB_XREF=gi:4500033 /UG=Hs.16074 Homo sapiens mRNA; cDNA DKFZp564I153 (from clone DKFZp564I153) AL049278 216023_at AK026040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026040.1 /DEF=Homo sapiens cDNA: FLJ22387 fis, clone HRC07655. /FEA=mRNA /DB_XREF=gi:10438753 /UG=Hs.306827 Homo sapiens cDNA: FLJ22387 fis, clone HRC07655 AK026040 lysine (K)-specific demethylase 4B KDM4B 23030 NM_015015 /// XM_005259521 /// XM_005259522 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 216024_at AK023207 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023207.1 /DEF=Homo sapiens cDNA FLJ13145 fis, clone NT2RP3003282, highly similar to Homo sapiens dynamin (DNM) mRNA. /FEA=mRNA /DB_XREF=gi:10435030 /UG=Hs.167013 dynamin 2 AK023207 dynamin 2 DNM2 1785 NM_001005360 /// NM_001005361 /// NM_001005362 /// NM_001190716 /// NM_004945 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048489 // synaptic vesicle transport // non-traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0008017 // microtubule binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 216025_x_at M21940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M21940.1 /DEF=Human cytochrome P-450 S-mephenytoin 4-hydroxylase (P-450mp) mRNA, 3 end, clone MP-4. /FEA=mRNA /GEN=CYP2C /DB_XREF=gi:181365 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 M21940 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 216026_s_at AL080203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080203.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F222 (from clone DKFZp434F222); partial cds. /FEA=mRNA /GEN=DKFZp434F222 /PROD=hypothetical protein /DB_XREF=gi:5262688 /UG=Hs.166846 polymerase (DNA directed), epsilon AL080203 polymerase (DNA directed), epsilon, catalytic subunit POLE 5426 NM_006231 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0071897 // DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008622 // epsilon DNA polymerase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 216027_at AI005473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI005473 /FEA=EST /DB_XREF=gi:3214983 /DB_XREF=est:ou14c07.x1 /CLONE=IMAGE:1626252 /UG=Hs.169358 hypothetical protein AI005473 thioredoxin-related transmembrane protein 4 TMX4 56255 NM_021156 0006457 // protein folding // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded 216028_at AL049980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049980.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C152 (from clone DKFZp564C152). /FEA=mRNA /GEN=DKFZp564C152 /PROD=hypothetical protein /DB_XREF=gi:4884230 /UG=Hs.184216 DKFZP564C152 protein AL049980 216029_at AU159412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159412 /FEA=EST /DB_XREF=gi:11020933 /DB_XREF=est:AU159412 /CLONE=THYRO1001602 /UG=Hs.296756 Homo sapiens cDNA FLJ14348 fis, clone THYRO1001602 AU159412 216030_s_at AL049767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049767 /DEF=Human DNA sequence from clone 172H20 on chromosome 20q12-13.12 Contains genes for semenogelin I and II and PI3 (protease inhibitor 3, skin-derived (SKALP)), ESTs and GSSs /FEA=mRNA_1 /DB_XREF=gi:10198636 /UG=Hs.180016 semenogelin II AL049767 semenogelin II SEMG2 6407 NM_003008 0019953 // sexual reproduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 216031_x_at T53900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T53900 /FEA=EST /DB_XREF=gi:655761 /DB_XREF=est:yb83e08.r1 /CLONE=IMAGE:77798 /UG=Hs.172035 hypothetical protein similar to mouse HN1 (Hematological and Neurological expressed sequence 1) T53900 hematological and neurological expressed 1-like HN1L 90861 NM_144570 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 216032_s_at AF091085 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF091085.1 /DEF=Homo sapiens clone 638 unknown mRNA, complete sequence. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3860007 /UG=Hs.169992 hypothetical 43.2 Kd protein AF091085 ERGIC and golgi 3 ERGIC3 51614 NM_015966 /// NM_198398 /// XM_006723804 /// XM_006723805 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 216033_s_at S74774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S74774.1 /DEF=p59fyn(T)=OKT3-induced calcium influx regulator human, Jurkat J6 T cell line, mRNA Partial, 1605 nt. /FEA=CDS /PROD=tyrosine kinase p59fyn(T) /DB_XREF=gi:802050 /UG=Hs.169370 FYN oncogene related to SRC, FGR, YES S74774 FYN proto-oncogene, Src family tyrosine kinase FYN 2534 NM_001242779 /// NM_002037 /// NM_153047 /// NM_153048 /// XM_005266887 /// XM_005266888 /// XM_005266889 /// XM_005266890 /// XM_005266892 /// XM_006715429 0001764 // neuron migration // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007612 // learning // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 1900182 // positive regulation of protein localization to nucleus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042608 // T cell receptor binding // inferred from electronic annotation /// 0042609 // CD4 receptor binding // inferred from electronic annotation /// 0042610 // CD8 receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation /// 0070851 // growth factor receptor binding // inferred from physical interaction 216034_at AA558468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA558468 /FEA=EST /DB_XREF=gi:2328945 /DB_XREF=est:nk39c06.s1 /CLONE=IMAGE:1015882 /UG=Hs.178665 Homo sapiens immunoglobulin lambda gene locus DNA, clone:288A10 AA558468 zinc finger protein 280A ZNF280A 129025 NM_080740 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216035_x_at AV721430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV721430 /FEA=EST /DB_XREF=gi:10818582 /DB_XREF=est:AV721430 /CLONE=HTBBIF09 /UG=Hs.173638 transcription factor 7-like 2 (T-cell specific, HMG-box) AV721430 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 216036_x_at AK001734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001734.1 /DEF=Homo sapiens cDNA FLJ10872 fis, clone NT2RP4001725, weakly similar to GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT. /FEA=mRNA /DB_XREF=gi:7023179 /UG=Hs.172825 KIAA1037 protein AK001734 WD and tetratricopeptide repeats 1 WDTC1 23038 NM_001276252 /// NM_015023 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0055082 // cellular chemical homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation 216037_x_at AA664011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA664011 /FEA=EST /DB_XREF=gi:2618002 /DB_XREF=est:ac03f10.s1 /CLONE=IMAGE:855403 /UG=Hs.173638 transcription factor 7-like 2 (T-cell specific, HMG-box) AA664011 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 216038_x_at BE965715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE965715 /FEA=EST /DB_XREF=gi:11770370 /DB_XREF=est:601659774R1 /CLONE=IMAGE:3896034 /UG=Hs.180224 death-associated protein 6 BE965715 death-domain associated protein DAXX 1616 NM_001141969 /// NM_001141970 /// NM_001254717 /// NM_001350 /// XM_005248860 /// XM_005275218 /// XM_005275354 0000281 // mitotic cytokinesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from genetic interaction /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 1901216 // positive regulation of neuron death // inferred from genetic interaction /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0031072 // heat shock protein binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 216039_at D38503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38503.1 /DEF=Human PMS8 mRNA (yeast mismatch repair gene PMS1 homologue), partial cds (C-terminal region). /FEA=mRNA /GEN=PMS8 /DB_XREF=gi:559338 /UG=Hs.180121 postmeiotic segregation increased 2-like 6 D38503 gamma-aminobutyric acid (GABA) A receptor, alpha 2 GABRA2 2555 NM_000807 /// NM_001114175 /// NM_001286827 /// XM_005248080 /// XM_006714002 0001505 // regulation of neurotransmitter levels // inferred from mutant phenotype /// 0006298 // mismatch repair // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003684 // damaged DNA binding // traceable author statement /// 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // inferred from mutant phenotype 216040_x_at AK024135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024135.1 /DEF=Homo sapiens cDNA FLJ14073 fis, clone HEMBB1001812. /FEA=mRNA /DB_XREF=gi:10436441 /UG=Hs.296751 Homo sapiens cDNA FLJ14073 fis, clone HEMBB1001812 AK024135 216041_x_at AK023348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023348.1 /DEF=Homo sapiens cDNA FLJ13286 fis, clone OVARC1001154, highly similar to Homo sapiens clone 24720 epithelin 1 and 2 mRNA. /FEA=mRNA /DB_XREF=gi:10435243 /UG=Hs.180577 granulin AK023348 granulin GRN 2896 NM_001012479 /// NM_002087 /// XM_005257253 0001835 // blastocyst hatching // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 216042_at AI275938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI275938 /FEA=EST /DB_XREF=gi:3898212 /DB_XREF=est:qw05c07.x1 /CLONE=IMAGE:1990188 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) AI275938 tumor necrosis factor receptor superfamily, member 25 TNFRSF25 8718 NM_001039664 /// NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148974 0006915 // apoptotic process // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement 216043_x_at AK024135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024135.1 /DEF=Homo sapiens cDNA FLJ14073 fis, clone HEMBB1001812. /FEA=mRNA /DB_XREF=gi:10436441 /UG=Hs.296751 Homo sapiens cDNA FLJ14073 fis, clone HEMBB1001812 AK024135 216044_x_at AK027146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027146.1 /DEF=Homo sapiens cDNA: FLJ23493 fis, clone LNG01831, highly similar to HSU66589 Human ribosomal protein L5 pseudogene mRNA. /FEA=mRNA /DB_XREF=gi:10440199 /UG=Hs.180946 ribosomal protein L5 AK027146 family with sequence similarity 69, member A FAM69A 388650 NM_001006605 /// NM_001252269 /// NM_001252270 /// NM_001252271 /// NM_001252273 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 216045_at AB011137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB011137.2 /DEF=Homo sapiens mRNA for KIAA0565 protein, partial cds. /FEA=mRNA /GEN=KIAA0565 /PROD=KIAA0565 protein /DB_XREF=gi:6683716 /UG=Hs.300938 KIAA0565 gene product AB011137 coiled-coil domain containing 144A CCDC144A 9720 NM_014695 /// XM_005256877 /// XM_006721607 /// XM_006721608 216046_at AL109726 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109726.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 124430. /FEA=mRNA /DB_XREF=gi:5689792 /UG=Hs.187513 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 124430 AL109726 216047_x_at AL050253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050253.1 /DEF=H.sapiens mRNA similar to D29763 mouse mRNA for seizure-related gene product 6. Shares domains with BMPs, Tolloid, Sushi repeat proteins. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4886438 /UG=Hs.194766 seizure related gene 6 (mouse)-like AL050253 seizure related 6 homolog (mouse)-like SEZ6L 23544 NM_001184773 /// NM_001184774 /// NM_001184775 /// NM_001184776 /// NM_001184777 /// NM_021115 /// XM_005261439 /// XM_005261440 /// XM_006724195 /// XM_006724196 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 216048_s_at AK023621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023621.1 /DEF=Homo sapiens cDNA FLJ13559 fis, clone PLACE1007852, highly similar to Homo sapiens mRNA for KIAA0878 protein. /FEA=mRNA /DB_XREF=gi:10435602 /UG=Hs.188006 KIAA0878 protein AK023621 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 216049_at AK023621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023621.1 /DEF=Homo sapiens cDNA FLJ13559 fis, clone PLACE1007852, highly similar to Homo sapiens mRNA for KIAA0878 protein. /FEA=mRNA /DB_XREF=gi:10435602 /UG=Hs.188006 KIAA0878 protein AK023621 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 216050_at AK024584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024584.1 /DEF=Homo sapiens cDNA: FLJ20931 fis, clone ADSE01282. /FEA=mRNA /DB_XREF=gi:10436896 /UG=Hs.203076 Homo sapiens cDNA: FLJ20931 fis, clone ADSE01282 AK024584 216051_x_at AK022045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022045.1 /DEF=Homo sapiens cDNA FLJ11983 fis, clone HEMBB1001337. /FEA=mRNA /DB_XREF=gi:10433364 /UG=Hs.193162 Homo sapiens cDNA FLJ11983 fis, clone HEMBB1001337 AK022045 216052_x_at AF115765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF115765 /DEF=Homo sapiens Artemin gene, alternative forms, complete cds /FEA=CDS_1 /DB_XREF=gi:4235098 /UG=Hs.194689 artemin AF115765 artemin ARTN 9048 NM_001136215 /// NM_003976 /// NM_057090 /// NM_057091 /// NM_057160 /// XM_006711023 /// XM_006711024 0007165 // signal transduction // traceable author statement /// 0007405 // neuroblast proliferation // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0097021 // lymphocyte migration into lymphoid organs // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 216053_x_at AI143919 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI143919 /FEA=EST /DB_XREF=gi:3665728 /DB_XREF=est:qd99f12.x1 /CLONE=IMAGE:1737647 /UG=Hs.193783 Human DNA sequence from clone RP13-329D4 on chromosome 20 Contains ESTs, STSs, GSSs and a CpG island. Contains the 3 part of a novel gene, a gene similar to NCOR1 for a truncated form of nuclear receptor co-repressor 1 (retinoid X receptor interacting pr AI143919 family with sequence similarity 182, member A /// family with sequence similarity 182, member B /// family with sequence similarity 27, member B /// family with sequence similarity 27, member C FAM182A /// FAM182B /// FAM27B /// FAM27C 284800 /// 728882 /// 100132948 /// 100133121 NM_001024942 /// NM_182583 /// NR_024060 /// NR_026713 /// NR_026714 /// NR_027061 /// NR_027421 /// NR_027422 216054_x_at X58851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X58851 /DEF=Human MLC1emb gene for embryonic myosin alkaline light chain, promoter and exon 1 /FEA=mRNA /DB_XREF=gi:34680 /UG=Hs.298161 myosin, light polypeptide 4, alkali; atrial, embryonic X58851 myosin, light chain 4, alkali; atrial, embryonic MYL4 4635 NM_001002841 /// NM_002476 /// XM_005257391 /// XM_005257392 0002026 // regulation of the force of heart contraction // inferred from mutant phenotype /// 0007517 // muscle organ development // non-traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0031672 // A band // inferred from mutant phenotype 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0032038 // myosin II heavy chain binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from mutant phenotype 216055_at AK022920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022920.1 /DEF=Homo sapiens cDNA FLJ12858 fis, clone NT2RP2003517, highly similar to Human c-sisplatelet-derived growth factor 2 (SISPDGF2) mRNA. /FEA=mRNA /DB_XREF=gi:10434589 /UG=Hs.1976 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) AK022920 platelet-derived growth factor beta polypeptide PDGFB 5155 NM_002608 /// NM_033016 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009611 // response to wounding // non-traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038001 // paracrine signaling // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072255 // metanephric glomerular mesangial cell development // inferred from sequence or structural similarity /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072264 // metanephric glomerular endothelium development // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay /// 2000591 // positive regulation of metanephric mesenchymal cell migration // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 216056_at AW851559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW851559 /FEA=EST /DB_XREF=gi:7947076 /DB_XREF=est:IL3-CT0221-040400-107-E09 /UG=Hs.202695 Human soluble CD44 (CD44) mRNA, with exon v9 extension, partial cds AW851559 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 216057_at AK021928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021928.1 /DEF=Homo sapiens cDNA FLJ11866 fis, clone HEMBA1006973, highly similar to Homo sapiens rab3-GAP regulatory domain mRNA. /FEA=mRNA /DB_XREF=gi:10433227 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) AK021928 RAB3 GTPase activating protein subunit 2 (non-catalytic) RAB3GAP2 25782 NM_012414 0006886 // intracellular protein transport // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 216058_s_at X65962 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X65962.1 /DEF=H.sapiens mRNA for cytochrome P-450. /FEA=mRNA /GEN=CYP 2C /PROD=cytochrome P-450 II C /DB_XREF=gi:30158 /UG=Hs.296816 H.sapiens mRNA for cytochrome P-450 X65962 cytochrome P450, family 2, subfamily C, polypeptide 19 CYP2C19 1557 NM_000769 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 216059_at U02309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02309.1 /DEF=Human PAX-3 mRNA, partial cds. /FEA=mRNA /GEN=PAX-3 /DB_XREF=gi:435420 /UG=Hs.198 paired box gene 3 (Waardenburg syndrome 1) U02309 paired box 3 PAX3 5077 NM_000438 /// NM_001127366 /// NM_013942 /// NM_181457 /// NM_181458 /// NM_181459 /// NM_181460 /// NM_181461 /// XM_006712559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0060594 // mammary gland specification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0071837 // HMG box domain binding // inferred from electronic annotation 216060_s_at AK021890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021890.1 /DEF=Homo sapiens cDNA FLJ11828 fis, clone HEMBA1006507, weakly similar to DIAPHANOUS PROTEIN HOMOLOG 2. /FEA=mRNA /DB_XREF=gi:10433178 /UG=Hs.197751 KIAA0666 protein AK021890 dishevelled associated activator of morphogenesis 1 DAAM1 23002 NM_001270520 /// NM_014992 /// XM_005267430 /// XM_005267431 /// XR_429298 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 216061_x_at AU150748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150748 /FEA=EST /DB_XREF=gi:11012269 /DB_XREF=est:AU150748 /CLONE=NT2RP2003517 /UG=Hs.1976 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) AU150748 platelet-derived growth factor beta polypeptide PDGFB 5155 NM_002608 /// NM_033016 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009611 // response to wounding // non-traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038001 // paracrine signaling // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072255 // metanephric glomerular mesangial cell development // inferred from sequence or structural similarity /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072264 // metanephric glomerular endothelium development // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay /// 2000591 // positive regulation of metanephric mesenchymal cell migration // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 216062_at AW851559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW851559 /FEA=EST /DB_XREF=gi:7947076 /DB_XREF=est:IL3-CT0221-040400-107-E09 /UG=Hs.202695 Human soluble CD44 (CD44) mRNA, with exon v9 extension, partial cds AW851559 RP1-68D18.4 216063_at N55205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N55205 /FEA=EST /DB_XREF=gi:1198084 /DB_XREF=est:yv44g05.s1 /CLONE=IMAGE:245624 /UG=Hs.20205 hemoglobin, beta pseudogene 1 N55205 hemoglobin, beta pseudogene 1 HBBP1 3044 NR_001589 216064_s_at W27131 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W27131 /FEA=EST /DB_XREF=gi:1306665 /DB_XREF=est:22h11 /UG=Hs.207776 aspartylglucosaminidase W27131 aspartylglucosaminidase AGA 175 NM_000027 /// NM_001171988 /// NR_033655 /// XM_006714123 0006508 // proteolysis // inferred from electronic annotation /// 0006517 // protein deglycosylation // inferred from direct assay /// 0006517 // protein deglycosylation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 216065_at AL031228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031228 /DEF=Human DNA sequence from clone 1033B10 on chromosome 6p21.2-21.31. Contains the BING5 gene, exons 11 to 15 of the BING4 gene, the gene for GalT3 (beta3-Galactosyltransferase), the RPS18 (40S ribosomal protein S18) gene, the SACM2L (suppressor of ac... /FEA=mRNA_5 /DB_XREF=gi:3646023 /UG=Hs.204370 BING5 AL031228 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 B3GALT4 8705 NM_003782 0006486 // protein glycosylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047915 // ganglioside galactosyltransferase activity // inferred from electronic annotation 216066_at AK024328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024328.1 /DEF=Homo sapiens cDNA FLJ14266 fis, clone PLACE1002437, highly similar to ATP-BINDING CASSETTE TRANSPORTER 1. /FEA=mRNA /DB_XREF=gi:10436685 /UG=Hs.211562 ATP-binding cassette, sub-family A (ABC1), member 1 AK024328 ATP-binding cassette, sub-family A (ABC1), member 1 ABCA1 19 NM_005502 /// XM_005251773 /// XM_005251774 /// XM_005251776 /// XM_005251778 /// XM_005251780 /// XM_006716995 0002790 // peptide secretion // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0060155 // platelet dense granule organization // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008509 // anion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0019905 // syntaxin binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 216067_at AU145203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145203 /FEA=EST /DB_XREF=gi:11006724 /DB_XREF=est:AU145203 /CLONE=HEMBA1004193 /UG=Hs.300897 Homo sapiens cDNA FLJ11624 fis, clone HEMBA1004193 AU145203 216068_at AL110248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110248.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N021 (from clone DKFZp434N021). /FEA=mRNA /DB_XREF=gi:5817198 /UG=Hs.208769 Homo sapiens mRNA; cDNA DKFZp434N021 (from clone DKFZp434N021) AL110248 216069_at AL050065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050065.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566M043 (from clone DKFZp566M043). /FEA=mRNA /DB_XREF=gi:4884295 /UG=Hs.212587 Homo sapiens mRNA; cDNA DKFZp566M043 (from clone DKFZp566M043) AL050065 protein arginine methyltransferase 2 PRMT2 3275 NM_001242864 /// NM_001242865 /// NM_001242866 /// NM_001286676 /// NM_001286677 /// NM_001286678 /// NM_001535 /// NM_206962 /// XM_005261111 /// XM_006723998 /// XM_006723999 /// XM_006724000 0006479 // protein methylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048588 // developmental cell growth // inferred from sequence or structural similarity /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035189 // Rb-E2F complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0008469 // histone-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0033142 // progesterone receptor binding // inferred from physical interaction /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 216070_at AL049331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049331.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564I066 (from clone DKFZp564I066). /FEA=mRNA /DB_XREF=gi:4500106 /UG=Hs.207805 Homo sapiens mRNA; cDNA DKFZp564I066 (from clone DKFZp564I066) AL049331 216071_x_at AF132033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF132033 /DEF=Homo sapiens OPA-containing protein (HOPA) gene, complete cds /FEA=mRNA /DB_XREF=gi:5524202 /UG=Hs.211607 trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) AF132033 mediator complex subunit 12 MED12 9968 NM_005120 /// XM_005262317 /// XM_005262319 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090245 // axis elongation involved in somitogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 216072_at AL050065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050065.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566M043 (from clone DKFZp566M043). /FEA=mRNA /DB_XREF=gi:4884295 /UG=Hs.212587 Homo sapiens mRNA; cDNA DKFZp566M043 (from clone DKFZp566M043) AL050065 /// destrin (actin depolymerizing factor) pseudogene 1 DSTNP1 /// DSTNP1 216073_at AL109678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109678.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 28993. /FEA=mRNA /DB_XREF=gi:5689803 /UG=Hs.21597 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 28993 AL109678 ankyrin repeat domain 34C ANKRD34C 390616 NM_001146341 0005515 // protein binding // inferred from electronic annotation 216074_x_at AK001727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001727.1 /DEF=Homo sapiens cDNA FLJ10865 fis, clone NT2RP4001610, highly similar to Homo sapiens mRNA for KIAA0869 protein. /FEA=mRNA /DB_XREF=gi:7023167 /UG=Hs.21543 KIAA0869 protein AK001727 WW and C2 domain containing 1 WWC1 23286 NM_001161661 /// NM_001161662 /// NM_015238 /// XM_005265850 /// XM_005265851 /// XM_005265852 /// XM_005265853 /// XM_006714835 /// XM_006714836 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0032386 // regulation of intracellular transport // traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay 216075_at AF119418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF119418.1 /DEF=Homo sapiens nonfunctional GM3 synthase mRNA, alternatively spliced, complete sequence. /FEA=mRNA /DB_XREF=gi:7670075 /UG=Hs.225939 sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) AF119418 216076_at AW445040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW445040 /FEA=EST /DB_XREF=gi:6986802 /DB_XREF=est:UI-H-BI3-aka-h-09-0-UI.s1 /CLONE=IMAGE:2733928 /UG=Hs.300863 lethal (3) malignant brain tumor l(3)mbt protein (Drosophila) homolog AW445040 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216077_s_at AW445040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW445040 /FEA=EST /DB_XREF=gi:6986802 /DB_XREF=est:UI-H-BI3-aka-h-09-0-UI.s1 /CLONE=IMAGE:2733928 /UG=Hs.300863 lethal (3) malignant brain tumor l(3)mbt protein (Drosophila) homolog AW445040 l(3)mbt-like 1 (Drosophila) L3MBTL1 26013 NM_015478 /// NM_032107 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from direct assay /// 0030097 // hemopoiesis // inferred from expression pattern /// 0045652 // regulation of megakaryocyte differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from direct assay /// 0031493 // nucleosomal histone binding // inferred from direct assay /// 0032093 // SAM domain binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from physical interaction /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216078_at AL109681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109681.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 112333. /FEA=mRNA /DB_XREF=gi:5689785 /UG=Hs.226017 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 112333 AL109681 216079_at AK022721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022721.1 /DEF=Homo sapiens cDNA FLJ12659 fis, clone NT2RM4002161, highly similar to Homo sapiens laforin (EPM2A) mRNA. /FEA=mRNA /DB_XREF=gi:10434284 /UG=Hs.22464 epilepsy, progressive myoclonus type 2, Lafora disease (laforin) AK022721 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) EPM2A 7957 NM_001018041 /// NM_005670 /// XM_006715564 /// XM_006715565 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // non-traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // not recorded /// 0046959 // habituation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019203 // carbohydrate phosphatase activity // not recorded /// 0019203 // carbohydrate phosphatase activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 2001070 // starch binding // inferred from electronic annotation 216080_s_at AC004770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004770 /DEF=Homo sapiens chromosome 11, BAC CIT-HSP-311e8 (BC269730) containing the hFEN1 gene /FEA=CDS_3 /DB_XREF=gi:3212836 /UG=Hs.21765 fatty acid desaturase 3 AC004770 fatty acid desaturase 3 FADS3 3995 NM_021727 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 216081_at AK027151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027151.1 /DEF=Homo sapiens cDNA: FLJ23498 fis, clone LNG02683. /FEA=mRNA /DB_XREF=gi:10440206 /UG=Hs.306904 Homo sapiens cDNA: FLJ23498 fis, clone LNG02683 AK027151 laminin, alpha 4 LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement 216082_at AK022450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022450.1 /DEF=Homo sapiens cDNA FLJ12388 fis, clone MAMMA1002655, highly similar to Homo sapiens mRNA for ganglioside sialidase. /FEA=mRNA /DB_XREF=gi:10433850 /UG=Hs.225947 sialidase 3 (membrane sialidase) AK022450 sialidase 3 (membrane sialidase) NEU3 10825 NM_006656 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004308 // exo-alpha-sialidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016997 // alpha-sialidase activity // inferred from direct assay /// 0052794 // exo-alpha-(2->3)-sialidase activity // inferred from sequence or structural similarity /// 0052795 // exo-alpha-(2->6)-sialidase activity // inferred from electronic annotation /// 0052796 // exo-alpha-(2->8)-sialidase activity // inferred from sequence or structural similarity 216083_s_at AK022450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022450.1 /DEF=Homo sapiens cDNA FLJ12388 fis, clone MAMMA1002655, highly similar to Homo sapiens mRNA for ganglioside sialidase. /FEA=mRNA /DB_XREF=gi:10433850 /UG=Hs.225947 sialidase 3 (membrane sialidase) AK022450 sialidase 3 (membrane sialidase) NEU3 10825 NM_006656 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004308 // exo-alpha-sialidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016997 // alpha-sialidase activity // inferred from direct assay /// 0052794 // exo-alpha-(2->3)-sialidase activity // inferred from sequence or structural similarity /// 0052795 // exo-alpha-(2->6)-sialidase activity // inferred from electronic annotation /// 0052796 // exo-alpha-(2->8)-sialidase activity // inferred from sequence or structural similarity 216084_at AL080137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080137.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434J193 (from clone DKFZp434J193); partial cds. /FEA=mRNA /GEN=DKFZp434J193 /PROD=hypothetical protein /DB_XREF=gi:5262579 /UG=Hs.225999 DKFZP434J193 protein AL080137 transmembrane protein C9orf144B pseudogene FAM205B 389715 NM_001126494 /// NR_024481 216085_at AL080128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080128.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C153 (from clone DKFZp434C153); partial cds. /FEA=mRNA /GEN=DKFZp434C153 /PROD=hypothetical protein /DB_XREF=gi:5262565 /UG=Hs.225998 DKFZP434C153 protein AL080128 DKFZP434C153 protein /// obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF DKFZP434C153 /// OBSCN 26105 /// 84033 NM_001098623 /// NM_001271223 /// NM_052843 /// XM_005273287 /// XM_005273288 /// XM_005273289 /// XM_005273290 /// XM_005273291 /// XM_005273292 /// XM_005273293 /// XM_005273294 /// XM_005273295 /// XM_005273296 /// XM_005273297 /// XM_005273298 /// XM_005273299 /// XM_005273300 /// XM_005273301 /// XM_005273302 /// XM_005273304 /// XM_005273305 /// XM_005273307 /// XM_005273309 /// XM_005273310 /// XM_006711819 /// XM_006711820 /// XM_006711821 /// XM_006711822 /// XM_006711823 /// XM_006711824 /// XM_006711825 /// XM_006711826 /// XM_006711827 /// XM_006711828 /// XM_006711829 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0045214 // sarcomere organization // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030016 // myofibril // non-traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216086_at AB028977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028977.1 /DEF=Homo sapiens mRNA for KIAA1054 protein, partial cds. /FEA=mRNA /GEN=KIAA1054 /PROD=KIAA1054 protein /DB_XREF=gi:5689444 /UG=Hs.225974 KIAA1054 protein AB028977 synaptic vesicle glycoprotein 2C SV2C 22987 NM_014979 /// XM_005248470 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 216087_at AL078636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078636.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 117929. /FEA=mRNA /DB_XREF=gi:5051866 /UG=Hs.227171 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 117929 AL078636 216088_s_at AL078633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078633 /DEF=Human DNA sequence from clone RP5-1005F21 on chromosome 20 Contains three isoforms of the gene PSMA7 (proteasome (prosome, macropain) subunit, alpha type, 7), the gene HRH3 encoding the Histamine H3 receptor, the gene KIAA0693 (similar to SSXT, sy... /FEA=CDS_4 /DB_XREF=gi:9408092 /UG=Hs.233952 proteasome (prosome, macropain) subunit, alpha type, 7 AL078633 proteasome (prosome, macropain) subunit, alpha type, 7 PSMA7 5688 NM_002792 /// NM_152255 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 216089_at BE877397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE877397 /FEA=EST /DB_XREF=gi:10326173 /DB_XREF=est:601485434F1 /CLONE=IMAGE:3887936 /UG=Hs.240140 Human DNA sequence from clone 153G14 on chromosome 6p21.3-22.2. Contains the 3 end of the ZNF184 gene for Kruppel-like zinc finger protein 184, a gene for a PUTATIVE novel protein similar to worm F55A11.1 and T04F3.4, part of a gene for a novel C2H2 type BE877397 /// multiple coagulation factor deficiency 2 pseudogene 1 MCFD2P1 /// MCFD2P1 216090_x_at AL078636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078636.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 117929. /FEA=mRNA /DB_XREF=gi:5051866 /UG=Hs.227171 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 117929 AL078636 216091_s_at AF101784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF101784.1 /DEF=Homo sapiens b-TRCP variant E3RS-IkappaB mRNA, partial cds. /FEA=mRNA /PROD=b-TRCP variant E3RS-IkappaB /DB_XREF=gi:4165135 /UG=Hs.226434 beta-transducin repeat containing AF101784 beta-transducin repeat containing E3 ubiquitin protein ligase BTRC 8945 NM_001256856 /// NM_003939 /// NM_033637 /// XM_005270264 /// XM_006718054 /// XR_428727 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from direct assay /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 216092_s_at AL365347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL365347.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 298948. /FEA=mRNA /DB_XREF=gi:9187134 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 AL365347 solute carrier family 7 (amino acid transporter light chain, L system), member 8 SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 216093_at AL050053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050053.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566E103 (from clone DKFZp566E103). /FEA=mRNA /DB_XREF=gi:4884289 /UG=Hs.227397 Homo sapiens mRNA; cDNA DKFZp566E103 (from clone DKFZp566E103) AL050053 216094_at AK025323 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025323.1 /DEF=Homo sapiens cDNA: FLJ21670 fis, clone COL09010. /FEA=mRNA /DB_XREF=gi:10437816 /UG=Hs.230999 Homo sapiens cDNA: FLJ21670 fis, clone COL09010 AK025323 216095_x_at AF057354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF057354.1 /DEF=Homo sapiens myotubularin-related protein 1a mRNA, partial cds. /FEA=mRNA /PROD=myotubularin-related protein 1a /DB_XREF=gi:5138901 /UG=Hs.23200 myotubularin related protein 1 AF057354 myotubularin related protein 1 MTMR1 8776 NM_003828 /// NM_176789 /// XM_005274765 /// XM_005274766 /// XM_005274767 /// XM_005274768 /// XM_006724854 /// XM_006724855 /// XM_006724856 /// XR_247319 /// XR_430557 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from sequence or structural similarity /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 216096_s_at AF064842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF064842.1 /DEF=Homo sapiens map 2q30-p32; 202.6 cR from top repeat region, complete sequence. /FEA=mRNA /DB_XREF=gi:4206054 /UG=Hs.22998 neurexin 1 AF064842 neurexin 1 NRXN1 9378 NM_001135659 /// NM_004801 /// NM_138735 /// XM_005264642 /// XM_005264643 /// XM_006712133 /// XM_006712134 /// XM_006712135 /// XM_006712136 /// XM_006712137 /// XM_006712138 /// XM_006712139 /// XM_006712140 /// XM_006712141 /// XM_006712142 /// XM_006712143 /// XM_006712144 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0016339 // calcium-dependent cell-cell adhesion // inferred from sequence or structural similarity /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0023041 // neuronal signal transduction // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035418 // protein localization to synapse // inferred from sequence or structural similarity /// 0042297 // vocal learning // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0051490 // negative regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 0097091 // synaptic vesicle clustering // inferred from sequence or structural similarity /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097112 // gamma-aminobutyric acid receptor clustering // inferred from sequence or structural similarity /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from sequence or structural similarity /// 0097116 // gephyrin clustering // inferred from sequence or structural similarity /// 0097117 // guanylate kinase-associated protein clustering // inferred from sequence or structural similarity /// 0097118 // neuroligin clustering // inferred from sequence or structural similarity /// 0097119 // postsynaptic density protein 95 clustering // inferred from sequence or structural similarity /// 0097120 // receptor localization to synapse // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred by curator /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // traceable author statement /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005246 // calcium channel regulator activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0033130 // acetylcholine receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity /// 0097109 // neuroligin family protein binding // inferred from sequence or structural similarity 216097_at AF090910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090910.1 /DEF=Homo sapiens clone HQ0262. /FEA=mRNA /DB_XREF=gi:6690195 /UG=Hs.236760 Homo sapiens clone HQ0262 AF090910 216098_s_at U86813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U86813.1 /DEF=Homo sapiens serotonin-7 receptor pseudogene, complete sequence. /FEA=mRNA /PROD=serotonin-7 receptor /DB_XREF=gi:3138916 /UG=Hs.234784 Homo sapiens serotonin-7 receptor pseudogene, complete sequence U86813 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled /// 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 HTR7 /// HTR7P1 3363 /// 93164 NM_000872 /// NM_019859 /// NM_019860 /// NR_002774 0006939 // smooth muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0042310 // vasoconstriction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from electronic annotation 216099_at U86813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U86813.1 /DEF=Homo sapiens serotonin-7 receptor pseudogene, complete sequence. /FEA=mRNA /PROD=serotonin-7 receptor /DB_XREF=gi:3138916 /UG=Hs.234784 Homo sapiens serotonin-7 receptor pseudogene, complete sequence U86813 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 HTR7P1 93164 NR_002774 216100_s_at BG289527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG289527 /FEA=EST /DB_XREF=gi:13045417 /DB_XREF=est:602384379F1 /CLONE=IMAGE:4513362 /UG=Hs.234265 DKFZP586G011 protein BG289527 torsin A interacting protein 1 TOR1AIP1 26092 NM_001267578 /// NM_015602 /// NM_032678 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0071763 // nuclear membrane organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005521 // lamin binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 216101_at AL049242 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049242.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564B083 (from clone DKFZp564B083). /FEA=mRNA /DB_XREF=gi:4499977 /UG=Hs.234794 Homo sapiens mRNA; cDNA DKFZp564B083 (from clone DKFZp564B083) AL049242 216102_at AK021690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021690.1 /DEF=Homo sapiens cDNA FLJ11628 fis, clone HEMBA1004238. /FEA=mRNA /DB_XREF=gi:10432926 /UG=Hs.306610 Homo sapiens cDNA FLJ11628 fis, clone HEMBA1004238 AK021690 pleckstrin homology-like domain, family B, member 1 PHLDB1 23187 NM_001144758 /// NM_001144759 /// NM_015157 /// XM_005271468 /// XM_005271469 /// XM_005271470 /// XM_005271471 /// XM_005271472 /// XM_005271473 /// XM_005271474 /// XM_005271475 /// XM_005271477 /// XM_005277680 /// XM_006718796 /// XM_006718797 /// XM_006718798 /// XM_006718799 /// XM_006718800 /// XM_006718801 /// XM_006718802 /// XM_006718803 /// XM_006718804 /// XR_428972 216103_at AB014607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB014607.1 /DEF=Homo sapiens mRNA for KIAA0707 protein, partial cds. /FEA=mRNA /GEN=KIAA0707 /PROD=KIAA0707 protein /DB_XREF=gi:3327227 /UG=Hs.234786 KIAA0707 protein AB014607 acyl-CoA thioesterase 11 ACOT11 26027 NM_015547 /// NM_147161 0006631 // fatty acid metabolic process // non-traceable author statement /// 0009266 // response to temperature stimulus // inferred from sequence or structural similarity /// 0009409 // response to cold // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // traceable author statement 216104_at AF090910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090910.1 /DEF=Homo sapiens clone HQ0262. /FEA=mRNA /DB_XREF=gi:6690195 /UG=Hs.236760 Homo sapiens clone HQ0262 AF090910 216105_x_at X86428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X86428 /DEF=Homo sapiens PTPA gene for phosphotyrosyl phosphatase activator, exon 1 and joined CDS /FEA=mRNA_2 /DB_XREF=gi:974836 /UG=Hs.236963 protein phosphatase 2A, regulatory subunit B (PR 53) X86428 protein phosphatase 2A activator, regulatory subunit 4 PPP2R4 5524 NM_001193397 /// NM_001271832 /// NM_021131 /// NM_178000 /// NM_178001 /// NM_178002 /// NM_178003 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0030472 // mitotic spindle organization in nucleus // not recorded /// 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008160 // protein tyrosine phosphatase activator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019211 // phosphatase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 216106_at AL109682 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109682.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35394. /FEA=mRNA /DB_XREF=gi:5689804 /UG=Hs.23777 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35394 AL109682 uncharacterized LOC145678 LOC145678 145678 216107_at AF218021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF218021.1 /DEF=Homo sapiens clone PP552 unknown mRNA. /FEA=mRNA /PROD=unknown /DB_XREF=gi:10441971 /UG=Hs.302127 Homo sapiens clone PP552 unknown mRNA AF218021 uncharacterized LOC100129503 PP13 100129503 XR_243769 216108_at AK024142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024142.1 /DEF=Homo sapiens cDNA FLJ14080 fis, clone HEMBB1002152. /FEA=mRNA /DB_XREF=gi:10436451 /UG=Hs.301905 Homo sapiens cDNA FLJ14080 fis, clone HEMBB1002152 AK024142 216109_at AK025348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025348.1 /DEF=Homo sapiens cDNA: FLJ21695 fis, clone COL09653. /FEA=mRNA /DB_XREF=gi:10437846 /UG=Hs.306803 Homo sapiens cDNA: FLJ21695 fis, clone COL09653 AK025348 mediator complex subunit 13-like MED13L 23389 NM_015335 /// XM_006719305 /// XM_006719306 /// XM_006719307 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation 216110_x_at AU147017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147017 /FEA=EST /DB_XREF=gi:11008538 /DB_XREF=est:AU147017 /CLONE=HEMBB1002152 /UG=Hs.301905 Homo sapiens cDNA FLJ14080 fis, clone HEMBB1002152 AU147017 AC068039.4 216111_x_at U38979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U38979 /DEF=Human PMS2 related (hPMSR3) gene, complete cds /FEA=CDS /DB_XREF=gi:1061423 /UG=Hs.301862 postmeiotic segregation increased 2-like 9 U38979 postmeiotic segregation increased 2 pseudogene 3 PMS2P3 5387 NM_001003686 /// NM_005395 /// NR_028059 0006298 // mismatch repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0032300 // mismatch repair complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 216112_at AU157200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157200 /FEA=EST /DB_XREF=gi:11018721 /DB_XREF=est:AU157200 /CLONE=PLACE1006617 /UG=Hs.301390 Homo sapiens cDNA FLJ13538 fis, clone PLACE1006617 AU157200 216113_at AF070566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070566.1 /DEF=Homo sapiens clones 24611 and 24705 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387934 /UG=Hs.302042 Homo sapiens clones 24611 and 24705 mRNA sequence AF070566 abl-interactor 2 ABI2 10152 NM_001282925 /// NM_001282926 /// NM_001282927 /// NM_001282932 /// NM_005759 /// XM_005246217 /// XM_005246218 /// XM_005246221 /// XM_005246222 /// XM_005246223 /// XM_005246224 /// XM_005246225 /// XM_005246226 /// XM_005246229 /// XM_006712174 /// XM_006712175 /// XM_006712176 /// XM_006712177 /// XM_006712178 /// XM_006712179 /// XM_006712180 /// XM_006712181 /// XM_006712182 /// XM_006712183 /// XM_006712184 /// XM_006712185 /// XM_006712186 0006928 // cellular component movement // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // non-traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0043010 // camera-type eye development // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // traceable author statement /// 0019900 // kinase binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 216114_at AL049430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049430.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H201 (from clone DKFZp586H201). /FEA=mRNA /DB_XREF=gi:4500210 /UG=Hs.302061 Homo sapiens mRNA; cDNA DKFZp586H201 (from clone DKFZp586H201) AL049430 NCK interacting protein with SH3 domain NCKIPSD 51517 NM_016453 /// NM_184231 /// XM_005265223 /// XM_006713205 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // non-traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 216115_at AK024873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024873.1 /DEF=Homo sapiens cDNA: FLJ21220 fis, clone COL00546. /FEA=mRNA /DB_XREF=gi:10437285 /UG=Hs.306713 Homo sapiens cDNA: FLJ21220 fis, clone COL00546 AK024873 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 216116_at AL049430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049430.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H201 (from clone DKFZp586H201). /FEA=mRNA /DB_XREF=gi:4500210 /UG=Hs.302061 Homo sapiens mRNA; cDNA DKFZp586H201 (from clone DKFZp586H201) AL049430 CELSR3 antisense RNA 1 (head to head) CELSR3-AS1 102724368 NR_111921 /// XR_427334 /// XR_427335 /// XR_427336 /// XR_431589 /// XR_431590 /// XR_431591 216117_at AK025114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025114.1 /DEF=Homo sapiens cDNA: FLJ21461 fis, clone COL04727. /FEA=mRNA /DB_XREF=gi:10437566 /UG=Hs.306768 Homo sapiens cDNA: FLJ21461 fis, clone COL04727 AK025114 exosome component 2 EXOSC2 23404 NM_001282708 /// NM_001282709 /// NM_014285 /// NR_104230 /// XM_005272176 /// XM_006717020 /// XM_006717021 /// XM_006717022 /// XM_006717023 /// XM_006717024 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000175 // 3'-5'-exoribonuclease activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008312 // 7S RNA binding // traceable author statement 216118_at AU148024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148024 /FEA=EST /DB_XREF=gi:11009545 /DB_XREF=est:AU148024 /CLONE=MAMMA1002392 /UG=Hs.302075 Homo sapiens cDNA FLJ12365 fis, clone MAMMA1002392 AU148024 216119_s_at AL109804 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109804 /DEF=Human DNA sequence from clone RP5-1009E24 on chromosome 20 Contains a novel gene encoding two isoforms similar to mouse sialoadhesin (a macrophage sialic acid binding receptor), a novel gene similar to KIAA0417, the CENPB gene (centromere protein ... /FEA=mRNA_2 /DB_XREF=gi:11121192 /UG=Hs.302111 Human DNA sequence from clone RP5-1009E24 on chromosome 20 Contains a novel gene encoding two isoforms similar to mouse sialoadhesin (a macrophage sialic acid binding receptor), a novel gene similar to KIAA0417, the CENPB gene (centromere protein B), the AL109804 sperm flagellar 1 SPEF1 25876 NM_015417 /// XM_005260683 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 216120_s_at X63575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63575.1 /DEF=H.sapiens mRNA for plasma membrane calcium ATPase. /FEA=mRNA /GEN=hPMCA2 /PROD=plasma membrane calcium ATPase /DB_XREF=gi:2193883 /UG=Hs.305923 ATPase, Ca++ transporting, plasma membrane 4 X63575 ATPase, Ca++ transporting, plasma membrane 2 ATP2B2 491 NM_001001331 /// NM_001683 /// XM_005265179 /// XM_006713175 /// XM_006713176 /// XM_006713177 /// XM_006713178 /// XM_006713179 /// XM_006713180 /// XM_006713181 /// XM_006713182 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006996 // organelle organization // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021692 // cerebellar Purkinje cell layer morphogenesis // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0040011 // locomotion // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045299 // otolith mineralization // inferred from electronic annotation /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from direct assay /// 0005388 // calcium-transporting ATPase activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030899 // calcium-dependent ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216121_at AL080106 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080106.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566O053 (from clone DKFZp566O053). /FEA=mRNA /DB_XREF=gi:5262531 /UG=Hs.306323 Homo sapiens mRNA; cDNA DKFZp566O053 (from clone DKFZp566O053) AL080106 216122_at AK024543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024543.1 /DEF=Homo sapiens cDNA: FLJ20890 fis, clone ADKA03323. /FEA=mRNA /DB_XREF=gi:10436848 /UG=Hs.306686 Homo sapiens cDNA: FLJ20890 fis, clone ADKA03323 AK024543 216123_x_at AK024158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024158.1 /DEF=Homo sapiens cDNA FLJ14096 fis, clone MAMMA1000752. /FEA=mRNA /DB_XREF=gi:10436469 /UG=Hs.303289 Homo sapiens cDNA FLJ14096 fis, clone MAMMA1000752 AK024158 216124_at AK024158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024158.1 /DEF=Homo sapiens cDNA FLJ14096 fis, clone MAMMA1000752. /FEA=mRNA /DB_XREF=gi:10436469 /UG=Hs.303289 Homo sapiens cDNA FLJ14096 fis, clone MAMMA1000752 AK024158 216125_s_at AF064606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF064606.1 /DEF=Homo sapiens KB07 protein mRNA, partial cds. /FEA=mRNA /PROD=KB07 protein /DB_XREF=gi:3152665 /UG=Hs.306242 Homo sapiens KB07 protein mRNA, partial cds AF064606 RAN binding protein 9 RANBP9 10048 NM_005493 /// XM_006714945 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 216126_at AK022418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022418.1 /DEF=Homo sapiens cDNA FLJ12356 fis, clone MAMMA1002339. /FEA=mRNA /DB_XREF=gi:10433811 /UG=Hs.306635 Homo sapiens cDNA FLJ12356 fis, clone MAMMA1002339 AK022418 216127_at Z84717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z84717.1 /DEF=Human DNA sequence from cDNA 16pHQG;19 from chromosome 16p13.3. /FEA=mRNA /DB_XREF=gi:1817571 /UG=Hs.306284 Human DNA sequence from cDNA 16pHQG;19 from chromosome 16p13.3 Z84717 protein disulfide isomerase family A, member 2 PDIA2 64714 NM_006849 0006457 // protein folding // not recorded /// 0006621 // protein retention in ER lumen // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // not recorded 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // not recorded 216128_at AF052173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052173.1 /DEF=Homo sapiens clone 24417 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360484 /UG=Hs.306253 Homo sapiens clone 24417 mRNA sequence AF052173 uncharacterized LOC101929597 /// tubulin folding cofactor D LOC101929597 /// TBCD 6904 /// 101929597 NM_001033052 /// NM_005993 /// XM_005256396 /// XM_005256399 /// XM_005256400 /// XM_005256401 /// XM_005256402 /// XM_005256403 /// XM_005256404 /// XM_005256405 /// XM_005275833 /// XM_006722290 /// XM_006722291 /// XM_006722292 /// XR_430033 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0034333 // adherens junction assembly // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 216129_at AL117659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117659.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586I0624 (from clone DKFZp586I0624). /FEA=mRNA /DB_XREF=gi:5912252 /UG=Hs.306353 Homo sapiens mRNA; cDNA DKFZp586I0624 (from clone DKFZp586I0624) AL117659 ATPase, class II, type 9A ATP9A 10079 NM_006045 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216130_at AK021633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021633.1 /DEF=Homo sapiens cDNA FLJ11571 fis, clone HEMBA1003328. /FEA=mRNA /DB_XREF=gi:10432853 /UG=Hs.306608 Homo sapiens cDNA FLJ11571 fis, clone HEMBA1003328 AK021633 216131_at AK000244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000244.1 /DEF=Homo sapiens cDNA FLJ20237 fis, clone COLF5879, highly similar to AB023230 Homo sapiens mRNA for KIAA1013 protein. /FEA=mRNA /DB_XREF=gi:7020196 /UG=Hs.306390 Homo sapiens cDNA FLJ20237 fis, clone COLF5879, highly similar to AB023230 Homo sapiens mRNA for KIAA1013 protein AK000244 FERM domain containing 4B FRMD4B 23150 NM_015123 /// XM_005264720 /// XM_005264721 /// XM_005264722 /// XM_005264723 /// XM_006713063 /// XM_006713064 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 216132_at AK021992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021992.1 /DEF=Homo sapiens cDNA FLJ11930 fis, clone HEMBB1000441. /FEA=mRNA /DB_XREF=gi:10433301 /UG=Hs.306618 Homo sapiens cDNA FLJ11930 fis, clone HEMBB1000441 AK021992 216133_at AA284903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA284903 /FEA=EST /DB_XREF=gi:1927445 /DB_XREF=est:zt24b05.r1 /CLONE=IMAGE:714033 /UG=Hs.306366 Homo sapiens T-cell receptor alpha delta locus from bases 501613 to 752736 (section 3 of 5) of the Complete Nucleotide Sequence AA284903 Homo sapiens mRNA for T cell receptor alpha variable 13, partial cds, clone: SEB 7. /// T cell receptor alpha variable 21 /// /// YME1-like 1 ATPase TCRA /// TRAV21 /// TRAV21 /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216134_at AK000244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000244.1 /DEF=Homo sapiens cDNA FLJ20237 fis, clone COLF5879, highly similar to AB023230 Homo sapiens mRNA for KIAA1013 protein. /FEA=mRNA /DB_XREF=gi:7020196 /UG=Hs.306390 Homo sapiens cDNA FLJ20237 fis, clone COLF5879, highly similar to AB023230 Homo sapiens mRNA for KIAA1013 protein AK000244 FERM domain containing 4B FRMD4B 23150 NM_015123 /// XM_005264720 /// XM_005264721 /// XM_005264722 /// XM_005264723 /// XM_006713063 /// XM_006713064 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 216135_at AK000122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000122.1 /DEF=Homo sapiens cDNA FLJ20115 fis, clone COL05594. /FEA=mRNA /DB_XREF=gi:7020002 /UG=Hs.306382 Homo sapiens cDNA FLJ20115 fis, clone COL05594 AK000122 IQ motif containing K IQCK 124152 NM_153208 /// XM_006721019 /// XR_243261 216136_at AF113683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113683.1 /DEF=Homo sapiens clone FLB3521. /FEA=mRNA /DB_XREF=gi:6855610 /UG=Hs.306569 Homo sapiens clone FLB3521 AF113683 216137_s_at AL031718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031718 /DEF=Human DNA sequence from clone LA16-371H6 on chromosome 16 Contains part of the gene for KIAA0516 protein, part of a gene similar to NDP kinase, ESTs, an STS and 2 CpG Islands /FEA=mRNA_1 /DB_XREF=gi:5805110 /UG=Hs.306437 Human DNA sequence from clone LA16-371H6 on chromosome 16 Contains part of the gene for KIAA0516 protein, part of a gene similar to NDP kinase, ESTs, an STS and 2 CpG Islands AL031718 mitogen-activated protein kinase 8 interacting protein 3 MAPK8IP3 23162 NM_001040439 /// NM_015133 /// XM_005255187 /// XM_005255188 /// XM_005255190 /// XM_006720868 /// XM_006720869 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation 0005078 // MAP-kinase scaffold activity // inferred from sequence or structural similarity /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 216138_at AL137285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137285.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D2416 (from clone DKFZp434D2416). /FEA=mRNA /DB_XREF=gi:6807740 /UG=Hs.306445 Homo sapiens mRNA; cDNA DKFZp434D2416 (from clone DKFZp434D2416) AL137285 216139_s_at AL031718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031718 /DEF=Human DNA sequence from clone LA16-371H6 on chromosome 16 Contains part of the gene for KIAA0516 protein, part of a gene similar to NDP kinase, ESTs, an STS and 2 CpG Islands /FEA=mRNA_1 /DB_XREF=gi:5805110 /UG=Hs.306437 Human DNA sequence from clone LA16-371H6 on chromosome 16 Contains part of the gene for KIAA0516 protein, part of a gene similar to NDP kinase, ESTs, an STS and 2 CpG Islands AL031718 mitogen-activated protein kinase 8 interacting protein 3 MAPK8IP3 23162 NM_001040439 /// NM_015133 /// XM_005255187 /// XM_005255188 /// XM_005255190 /// XM_006720868 /// XM_006720869 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from sequence or structural similarity /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005078 // MAP-kinase scaffold activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008432 // JUN kinase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation 216140_at AL137378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137378.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1126 (from clone DKFZp434K1126). /FEA=mRNA /DB_XREF=gi:6807908 /UG=Hs.306455 Homo sapiens mRNA; cDNA DKFZp434K1126 (from clone DKFZp434K1126) AL137378 216141_at AL137285 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137285.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D2416 (from clone DKFZp434D2416). /FEA=mRNA /DB_XREF=gi:6807740 /UG=Hs.306445 Homo sapiens mRNA; cDNA DKFZp434D2416 (from clone DKFZp434D2416) AL137285 216142_at AL137403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137403.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L092 (from clone DKFZp434L092). /FEA=mRNA /DB_XREF=gi:6807951 /UG=Hs.306457 Homo sapiens mRNA; cDNA DKFZp434L092 (from clone DKFZp434L092) AL137403 216143_at AL137403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137403.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L092 (from clone DKFZp434L092). /FEA=mRNA /DB_XREF=gi:6807951 /UG=Hs.306457 Homo sapiens mRNA; cDNA DKFZp434L092 (from clone DKFZp434L092) AL137403 216144_at AL137378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137378.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1126 (from clone DKFZp434K1126). /FEA=mRNA /DB_XREF=gi:6807908 /UG=Hs.306455 Homo sapiens mRNA; cDNA DKFZp434K1126 (from clone DKFZp434K1126) AL137378 216145_at AL137713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137713.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I0523 (from clone DKFZp434I0523). /FEA=mRNA /DB_XREF=gi:6808127 /UG=Hs.306465 Homo sapiens mRNA; cDNA DKFZp434I0523 (from clone DKFZp434I0523) AL137713 216146_at AF113683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113683.1 /DEF=Homo sapiens clone FLB3521. /FEA=mRNA /DB_XREF=gi:6855610 /UG=Hs.306569 Homo sapiens clone FLB3521 AF113683 216147_at AL353942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353942.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L23121 (from clone DKFZp761L23121). /FEA=mRNA /DB_XREF=gi:7669981 /UG=Hs.306504 Homo sapiens mRNA; cDNA DKFZp761L23121 (from clone DKFZp761L23121) AL353942 216148_at AL353942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353942.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L23121 (from clone DKFZp761L23121). /FEA=mRNA /DB_XREF=gi:7669981 /UG=Hs.306504 Homo sapiens mRNA; cDNA DKFZp761L23121 (from clone DKFZp761L23121) AL353942 216149_at AL359623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359623.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761J182 (from clone DKFZp761J182). /FEA=mRNA /DB_XREF=gi:8655701 /UG=Hs.306516 Homo sapiens mRNA; cDNA DKFZp761J182 (from clone DKFZp761J182) AL359623 leucine rich repeat containing 37B pseudogene 1 LRRC37BP1 147172 NM_207323 /// NR_015341 216150_at AK021609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021609.1 /DEF=Homo sapiens cDNA FLJ11547 fis, clone HEMBA1002934. /FEA=mRNA /DB_XREF=gi:10432824 /UG=Hs.306605 Homo sapiens cDNA FLJ11547 fis, clone HEMBA1002934 AK021609 216151_at AK021609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021609.1 /DEF=Homo sapiens cDNA FLJ11547 fis, clone HEMBA1002934. /FEA=mRNA /DB_XREF=gi:10432824 /UG=Hs.306605 Homo sapiens cDNA FLJ11547 fis, clone HEMBA1002934 AK021609 216152_at AK021633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021633.1 /DEF=Homo sapiens cDNA FLJ11571 fis, clone HEMBA1003328. /FEA=mRNA /DB_XREF=gi:10432853 /UG=Hs.306608 Homo sapiens cDNA FLJ11571 fis, clone HEMBA1003328 AK021633 216153_x_at AK022897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022897.1 /DEF=Homo sapiens cDNA FLJ12835 fis, clone NT2RP2003165. /FEA=mRNA /DB_XREF=gi:10434555 /UG=Hs.306641 Homo sapiens cDNA FLJ12835 fis, clone NT2RP2003165 AK022897 reversion-inducing-cysteine-rich protein with kazal motifs RECK 8434 NM_021111 /// XM_006716879 0001955 // blood vessel maturation // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 216154_at AF339787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF339787.1 /DEF=Homo sapiens clone IMAGE:205688, mRNA sequence. /FEA=mRNA /DB_XREF=gi:13507325 /UG=Hs.326722 Homo sapiens clone IMAGE:205688, mRNA sequence AF339787 216155_at AK024543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024543.1 /DEF=Homo sapiens cDNA: FLJ20890 fis, clone ADKA03323. /FEA=mRNA /DB_XREF=gi:10436848 /UG=Hs.306686 Homo sapiens cDNA: FLJ20890 fis, clone ADKA03323 AK024543 216156_at AK022897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022897.1 /DEF=Homo sapiens cDNA FLJ12835 fis, clone NT2RP2003165. /FEA=mRNA /DB_XREF=gi:10434555 /UG=Hs.306641 Homo sapiens cDNA FLJ12835 fis, clone NT2RP2003165 AK022897 reversion-inducing-cysteine-rich protein with kazal motifs RECK 8434 NM_021111 /// XM_006716879 0001955 // blood vessel maturation // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 216157_at AK024231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024231.1 /DEF=Homo sapiens cDNA FLJ14169 fis, clone NT2RP2002056. /FEA=mRNA /DB_XREF=gi:10436558 /UG=Hs.306670 Homo sapiens cDNA FLJ14169 fis, clone NT2RP2002056 AK024231 216158_at AK024123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024123.1 /DEF=Homo sapiens cDNA FLJ14061 fis, clone HEMBB1000749. /FEA=mRNA /DB_XREF=gi:10436427 /UG=Hs.306664 Homo sapiens cDNA FLJ14061 fis, clone HEMBB1000749 AK024123 216159_s_at AK023757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023757.1 /DEF=Homo sapiens cDNA FLJ13695 fis, clone PLACE2000124. /FEA=mRNA /DB_XREF=gi:10435786 /UG=Hs.306658 Homo sapiens cDNA FLJ13695 fis, clone PLACE2000124 AK023757 216160_at AK024231 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024231.1 /DEF=Homo sapiens cDNA FLJ14169 fis, clone NT2RP2002056. /FEA=mRNA /DB_XREF=gi:10436558 /UG=Hs.306670 Homo sapiens cDNA FLJ14169 fis, clone NT2RP2002056 AK024231 216161_at AK024128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024128.1 /DEF=Homo sapiens cDNA FLJ14066 fis, clone HEMBB1001197. /FEA=mRNA /DB_XREF=gi:10436433 /UG=Hs.306665 Homo sapiens cDNA FLJ14066 fis, clone HEMBB1001197 AK024128 strawberry notch homolog 1 (Drosophila) SBNO1 55206 NM_001167856 /// NM_018183 /// XM_005253572 /// XM_005253573 /// XM_005253575 /// XM_005253576 /// XM_006719473 /// XM_006719474 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 216162_at AK024128 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024128.1 /DEF=Homo sapiens cDNA FLJ14066 fis, clone HEMBB1001197. /FEA=mRNA /DB_XREF=gi:10436433 /UG=Hs.306665 Homo sapiens cDNA FLJ14066 fis, clone HEMBB1001197 AK024128 strawberry notch homolog 1 (Drosophila) SBNO1 55206 NM_001167856 /// NM_018183 /// XM_005253572 /// XM_005253573 /// XM_005253575 /// XM_005253576 /// XM_006719473 /// XM_006719474 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 216163_at AK025086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025086.1 /DEF=Homo sapiens cDNA: FLJ21433 fis, clone COL04232. /FEA=mRNA /DB_XREF=gi:10437530 /UG=Hs.306761 Homo sapiens cDNA: FLJ21433 fis, clone COL04232 AK025086 216164_at AK024867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024867.1 /DEF=Homo sapiens cDNA: FLJ21214 fis, clone COL00523. /FEA=mRNA /DB_XREF=gi:10437277 /UG=Hs.306710 Homo sapiens cDNA: FLJ21214 fis, clone COL00523 AK024867 216165_at AK025650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025650.1 /DEF=Homo sapiens cDNA: FLJ21997 fis, clone HEP06590. /FEA=mRNA /DB_XREF=gi:10438234 /UG=Hs.306820 Homo sapiens cDNA: FLJ21997 fis, clone HEP06590 AK025650 216166_at AK024909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024909.1 /DEF=Homo sapiens cDNA: FLJ21256 fis, clone COL01402. /FEA=mRNA /DB_XREF=gi:10437324 /UG=Hs.306724 Homo sapiens cDNA: FLJ21256 fis, clone COL01402 AK024909 216167_at AK024867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024867.1 /DEF=Homo sapiens cDNA: FLJ21214 fis, clone COL00523. /FEA=mRNA /DB_XREF=gi:10437277 /UG=Hs.306710 Homo sapiens cDNA: FLJ21214 fis, clone COL00523 AK024867 leucine rich repeat neuronal 2 LRRN2 10446 NM_006338 /// NM_201630 /// XM_005244827 /// XM_006711115 /// XM_006711116 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement 216168_at AK024909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024909.1 /DEF=Homo sapiens cDNA: FLJ21256 fis, clone COL01402. /FEA=mRNA /DB_XREF=gi:10437324 /UG=Hs.306724 Homo sapiens cDNA: FLJ21256 fis, clone COL01402 AK024909 216169_at AK025430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025430.1 /DEF=Homo sapiens cDNA: FLJ21777 fis, clone HEP00173. /FEA=mRNA /DB_XREF=gi:10437940 /UG=Hs.306811 Homo sapiens cDNA: FLJ21777 fis, clone HEP00173 AK025430 216170_at AK025271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025271.1 /DEF=Homo sapiens cDNA: FLJ21618 fis, clone COL07487. /FEA=mRNA /DB_XREF=gi:10437753 /UG=Hs.306790 Homo sapiens cDNA: FLJ21618 fis, clone COL07487 AK025271 216171_at AK025271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025271.1 /DEF=Homo sapiens cDNA: FLJ21618 fis, clone COL07487. /FEA=mRNA /DB_XREF=gi:10437753 /UG=Hs.306790 Homo sapiens cDNA: FLJ21618 fis, clone COL07487 AK025271 216172_at AK025114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025114.1 /DEF=Homo sapiens cDNA: FLJ21461 fis, clone COL04727. /FEA=mRNA /DB_XREF=gi:10437566 /UG=Hs.306768 Homo sapiens cDNA: FLJ21461 fis, clone COL04727 AK025114 216173_at AK025360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025360.1 /DEF=Homo sapiens cDNA: FLJ21707 fis, clone COL09953. /FEA=mRNA /DB_XREF=gi:10437861 /UG=Hs.306806 Homo sapiens cDNA: FLJ21707 fis, clone COL09953 AK025360 216174_at AK025343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025343.1 /DEF=Homo sapiens cDNA: FLJ21690 fis, clone COL09538. /FEA=mRNA /DB_XREF=gi:10437841 /UG=Hs.306802 Homo sapiens cDNA: FLJ21690 fis, clone COL09538 AK025343 hepatocellular carcinoma-related HCRP1 HCRP1 387535 NM_199220 /// XM_001725456 216175_at AK025276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025276.1 /DEF=Homo sapiens cDNA: FLJ21623 fis, clone COL07915. /FEA=mRNA /DB_XREF=gi:10437759 /UG=Hs.306791 Homo sapiens cDNA: FLJ21623 fis, clone COL07915 AK025276 216176_at AK025343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025343.1 /DEF=Homo sapiens cDNA: FLJ21690 fis, clone COL09538. /FEA=mRNA /DB_XREF=gi:10437841 /UG=Hs.306802 Homo sapiens cDNA: FLJ21690 fis, clone COL09538 AK025343 hepatocellular carcinoma-related HCRP1 HCRP1 387535 NM_199220 /// XM_001725456 216177_at AW582267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW582267 /FEA=EST /DB_XREF=gi:7257316 /DB_XREF=est:QV0-ST0215-060100-083-c06 /UG=Hs.306951 Human DNA sequence from clone RP11-375F2 on chromosome 1 Contains a pseudogene similar to UBL1 (ubiquitin-like 1 (sentrin)), a pseudogene similar to ribosomal protein L29, ESTs, STSs and GSSs AW582267 ribosomal protein L29 pseudogene 7 /// RPL29P7 /// RPL29P7 216178_x_at AA215854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA215854 /FEA=EST /DB_XREF=gi:1815801 /DB_XREF=est:csh0013.seq.F /UG=Hs.326526 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) AA215854 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ITGB1 3688 NM_002211 /// NM_033666 /// NM_033667 /// NM_033668 /// NM_033669 /// NM_133376 /// XM_005252448 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007161 // calcium-independent cell-matrix adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032594 // protein transport within lipid bilayer // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001726 // ruffle // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0001968 // fibronectin binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation 216179_x_at AK027173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027173.1 /DEF=Homo sapiens cDNA: FLJ23520 fis, clone LNG04926. /FEA=mRNA /DB_XREF=gi:10440239 /UG=Hs.306908 Homo sapiens cDNA: FLJ23520 fis, clone LNG04926 AK027173 216180_s_at AK026758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026758.1 /DEF=Homo sapiens cDNA: FLJ23105 fis, clone LNG07677. /FEA=mRNA /DB_XREF=gi:10439683 /UG=Hs.306877 Homo sapiens cDNA: FLJ23105 fis, clone LNG07677 AK026758 synaptojanin 2 SYNJ2 8871 NM_001178088 /// NM_003898 /// XM_005267197 /// XM_005267198 /// XM_005267199 /// XM_005267200 /// XM_006715591 /// XM_006715592 /// XR_245556 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 216181_at AK026758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026758.1 /DEF=Homo sapiens cDNA: FLJ23105 fis, clone LNG07677. /FEA=mRNA /DB_XREF=gi:10439683 /UG=Hs.306877 Homo sapiens cDNA: FLJ23105 fis, clone LNG07677 AK026758 synaptojanin 2 SYNJ2 8871 NM_001178088 /// NM_003898 /// XM_005267197 /// XM_005267198 /// XM_005267199 /// XM_005267200 /// XM_006715591 /// XM_006715592 /// XR_245556 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 216182_at AK026758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026758.1 /DEF=Homo sapiens cDNA: FLJ23105 fis, clone LNG07677. /FEA=mRNA /DB_XREF=gi:10439683 /UG=Hs.306877 Homo sapiens cDNA: FLJ23105 fis, clone LNG07677 AK026758 synaptojanin 2 SYNJ2 8871 NM_001178088 /// NM_003898 /// XM_005267197 /// XM_005267198 /// XM_005267199 /// XM_005267200 /// XM_006715591 /// XM_006715592 /// XR_245556 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 216183_at AL512703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512703.1 /DEF=Homo sapiens mRNA; cDNA DKFZp667H046 (from clone DKFZp667H046). /FEA=mRNA /GEN=DKFZp667H046 /PROD=hypothetical protein /DB_XREF=gi:12224942 /UG=Hs.307065 Homo sapiens mRNA; cDNA DKFZp667H046 (from clone DKFZp667H046) AL512703 transglutaminase 2 TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from mutant phenotype /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216184_s_at AF263310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF263310.1 /DEF=Homo sapiens rab3 interacting protein variant 6 mRNA, partial cds. /FEA=mRNA /PROD=rab3 interacting protein variant 6 /DB_XREF=gi:10799019 /UG=Hs.306955 Homo sapiens rab3 interacting protein variant 6 mRNA, partial cds AF263310 regulating synaptic membrane exocytosis 1 RIMS1 22999 NM_001168407 /// NM_001168408 /// NM_001168409 /// NM_001168410 /// NM_001168411 /// NM_014989 /// XM_005248685 /// XM_005248686 /// XM_005248687 /// XM_005248688 /// XM_005248690 /// XM_005248691 /// XM_006715383 /// XM_006715384 /// XM_006715385 /// XM_006715386 /// XM_006715387 /// XM_006715388 /// XM_006715389 /// XM_006715390 /// XM_006715391 /// XM_006715392 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0045055 // regulated secretory pathway // non-traceable author statement /// 0046903 // secretion // non-traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048791 // calcium ion-dependent exocytosis of neurotransmitter // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061025 // membrane fusion // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // non-traceable author statement /// 0045202 // synapse // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216185_at BC001879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001879.1 /DEF=Homo sapiens, clone IMAGE:3534181, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3534181) /DB_XREF=gi:12804862 /UG=Hs.306976 Homo sapiens, clone IMAGE:3534181, mRNA, partial cds BC001879 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) FUT9 10690 NM_006581 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017083 // 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 216186_at T90013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T90013 /FEA=EST /DB_XREF=gi:718526 /DB_XREF=est:yd38g03.s1 /CLONE=IMAGE:110548 /UG=Hs.307044 Homo sapiens C1orf20 gene, partial sequence T90013 216187_x_at AF222691 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF222691.1 /DEF=Homo sapiens Alu repeat (LNX1) mRNA sequence. /FEA=mRNA /DB_XREF=gi:12655850 /UG=Hs.307008 Homo sapiens Alu repeat (LNX1) mRNA sequence AF222691 216188_at BC002892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002892.1 /DEF=Homo sapiens, clone IMAGE:3940152, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3940152) /DB_XREF=gi:12804078 /UG=Hs.306984 Homo sapiens, clone IMAGE:3940152, mRNA, partial cds BC002892 MYCN opposite strand MYCNOS 10408 NM_006316 /// NR_026766 /// NR_110230 0007275 // multicellular organismal development // traceable author statement 216189_at BC002465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002465.1 /DEF=Homo sapiens, clone IMAGE:3344506, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3344506) /DB_XREF=gi:12803298 /UG=Hs.306993 Homo sapiens, clone IMAGE:3344506, mRNA, partial cds BC002465 216190_x_at AA215854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA215854 /FEA=EST /DB_XREF=gi:1815801 /DB_XREF=est:csh0013.seq.F /UG=Hs.326526 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) AA215854 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ITGB1 3688 NM_002211 /// NM_033666 /// NM_033667 /// NM_033668 /// NM_033669 /// NM_133376 /// XM_005252448 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007161 // calcium-independent cell-matrix adhesion // inferred from genetic interaction /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032594 // protein transport within lipid bilayer // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001726 // ruffle // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0034678 // integrin alpha8-beta1 complex // traceable author statement /// 0034679 // integrin alpha9-beta1 complex // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0001968 // fibronectin binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from electronic annotation 216191_s_at X72501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X72501.1 /DEF=H.sapiens mRNA for soluble delta TCR. /FEA=CDS /PROD=gamma-delta T-cell receptor /DB_XREF=gi:298104 /UG=Hs.307187 H.sapiens mRNA for soluble delta TCR X72501 T cell receptor delta variable 3 TRDV3 28516 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216192_at AL512688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512688.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547J2313 (from clone DKFZp547J2313). /FEA=mRNA /GEN=DKFZp547J2313 /PROD=hypothetical protein /DB_XREF=gi:12224841 /UG=Hs.307074 Homo sapiens mRNA; cDNA DKFZp547J2313 (from clone DKFZp547J2313) AL512688 fatty acid binding protein 7, brain FABP7 2173 NM_001446 /// XM_005266858 0001964 // startle response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0060134 // prepulse inhibition // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 216193_at X69637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X69637.1 /DEF=H.sapiens mRNA sequence (16p11.2). /FEA=mRNA /DB_XREF=gi:29573 /UG=Hs.307208 H.sapiens mRNA sequence (16p11.2) X69637 216194_s_at AD001527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AD001527 /DEF=Homo sapiens DNA from chromosome 19-cosmid f24590 containing CAPNS and POL2RI, genomic sequence /FEA=CDS_3 /DB_XREF=gi:1905899 /UG=Hs.31053 cytoskeleton-associated protein 1 AD001527 tubulin folding cofactor B TBCB 1155 NM_001281 /// XM_006722998 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement 0005515 // protein binding // inferred from physical interaction 216195_at AF131823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131823.1 /DEF=Homo sapiens clone 24997 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406659 /UG=Hs.308951 Homo sapiens clone 24997 mRNA sequence AF131823 ankyrin 2, neuronal ANK2 287 NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity 216196_at X69637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X69637.1 /DEF=H.sapiens mRNA sequence (16p11.2). /FEA=mRNA /DB_XREF=gi:29573 /UG=Hs.307208 H.sapiens mRNA sequence (16p11.2) X69637 hect domain and RLD 2 pseudogene 5 /// /// hect domain and RLD 2 pseudogene 8 /// HERC2P5 /// HERC2P5 /// HERC2P8 /// HERC2P8 216197_at AK021569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021569.1 /DEF=Homo sapiens cDNA FLJ11507 fis, clone HEMBA1002160. /FEA=mRNA /DB_XREF=gi:10432775 /UG=Hs.314347 Homo sapiens cDNA FLJ11507 fis, clone HEMBA1002160 AK021569 216198_at AK021569 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021569.1 /DEF=Homo sapiens cDNA FLJ11507 fis, clone HEMBA1002160. /FEA=mRNA /DB_XREF=gi:10432775 /UG=Hs.314347 Homo sapiens cDNA FLJ11507 fis, clone HEMBA1002160 AK021569 216199_s_at AL109942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109942 /DEF=Human DNA sequence from clone RP3-473J16 on chromosome 6q25.3-26 Contains 3 end of the MAP3K4 (mitogen-activated protein kinase kinase kinase 4) gene, a novel mRNA, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:8894643 /UG=Hs.32353 mitogen-activated protein kinase kinase kinase 4 AL109942 mitogen-activated protein kinase kinase kinase 4 MAP3K4 4216 NM_001291958 /// NM_005922 /// NM_006724 /// NR_120425 /// XM_005266988 /// XM_005266989 /// XR_245517 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019100 // male germ-line sex determination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0060718 // chorionic trophoblast cell differentiation // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216200_at AK025379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025379.1 /DEF=Homo sapiens cDNA: FLJ21726 fis, clone COLF1088. /FEA=mRNA /DB_XREF=gi:10437882 /UG=Hs.318721 Homo sapiens cDNA: FLJ21726 fis, clone COLF1088 AK025379 pleckstrin homology domain containing, family M (with RUN domain) member 1 PLEKHM1 9842 NM_014798 /// NR_027774 /// NR_027782 /// XM_006722201 /// XM_006722202 /// XM_006725277 /// XM_006725278 /// XM_006725632 /// XM_006725633 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 216201_at AK025239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025239.1 /DEF=Homo sapiens cDNA: FLJ21586 fis, clone COL06920. /FEA=mRNA /DB_XREF=gi:10437709 /UG=Hs.321142 Homo sapiens cDNA: FLJ21586 fis, clone COL06920 AK025239 216202_s_at U15555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U15555.1 /DEF=Human serine palmitoyltransferase (LCB2) mRNA, partial cds. /FEA=mRNA /GEN=LCB2 /PROD=serine palmitoyltransferase /DB_XREF=gi:1001944 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 U15555 serine palmitoyltransferase, long chain base subunit 2 SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 216203_at U15555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U15555.1 /DEF=Human serine palmitoyltransferase (LCB2) mRNA, partial cds. /FEA=mRNA /GEN=LCB2 /PROD=serine palmitoyltransferase /DB_XREF=gi:1001944 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 U15555 serine palmitoyltransferase, long chain base subunit 2 SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 216204_at BC005092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005092.1 /DEF=Homo sapiens, clone IMAGE:3843012, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3843012) /DB_XREF=gi:13477248 /UG=Hs.326730 Homo sapiens, clone IMAGE:3843012, mRNA, partial cds BC005092 catechol-O-methyltransferase COMT 1312 NM_000754 /// NM_001135161 /// NM_001135162 /// NM_007310 /// XM_005261229 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216205_s_at AK021947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021947.1 /DEF=Homo sapiens cDNA FLJ11885 fis, clone HEMBA1007203, highly similar to Homo sapiens mRNA for KIAA0214 protein. /FEA=mRNA /DB_XREF=gi:10433251 /UG=Hs.3363 KIAA0214 gene product AK021947 mitofusin 2 MFN2 9927 NM_001127660 /// NM_014874 /// XM_005263543 /// XM_005263545 /// XM_005263547 /// XM_005263548 0001825 // blastocyst formation // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051646 // mitochondrion localization // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031306 // intrinsic component of mitochondrial outer membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 216206_x_at BC005365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC005365.1 /DEF=Homo sapiens, clone IMAGE:3829438, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3829438) /DB_XREF=gi:13529199 /UG=Hs.331237 Homo sapiens, clone IMAGE:3829438, mRNA, partial cds BC005365 mitogen-activated protein kinase kinase 7 MAP2K7 5609 NM_145185 /// XM_005272489 /// XM_005272490 /// XM_006722800 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from sequence or structural similarity /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216207_x_at AW408194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW408194 /FEA=EST /DB_XREF=gi:6927251 /DB_XREF=est:UI-HF-BL0-abw-b-10-0-UI.r1 /CLONE=IMAGE:3057763 /UG=Hs.37089 immunoglobulin kappa variable 1-13 AW408194 immunoglobulin kappa constant IGKC 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 216208_s_at AU117487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU117487 /FEA=EST /DB_XREF=gi:10932459 /DB_XREF=est:AU117487 /CLONE=HEMBA1001510 /UG=Hs.42853 cAMP responsive element binding protein-like 1 AU117487 activating transcription factor 6 beta ATF6B 1388 NM_001136153 /// NM_004381 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216209_at AL137270 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137270.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G0614 (from clone DKFZp434G0614). /FEA=mRNA /DB_XREF=gi:6807705 /UG=Hs.39337 Homo sapiens mRNA; cDNA DKFZp434G0614 (from clone DKFZp434G0614) AL137270 long intergenic non-protein coding RNA 939 LINC00939 400084 NR_034132 216210_x_at AA046650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA046650 /FEA=EST /DB_XREF=gi:1524566 /DB_XREF=est:zk72e08.s1 /CLONE=IMAGE:488390 /UG=Hs.40342 putative nuclear protein AA046650 TRIO and F-actin binding protein TRIOBP 11078 NM_001039141 /// NM_007032 /// NM_138632 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030047 // actin modification // non-traceable author statement /// 0051016 // barbed-end actin filament capping // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0030496 // midbody // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0045159 // myosin II binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from direct assay 216211_at AL049233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049233.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A023 (from clone DKFZp564A023). /FEA=mRNA /DB_XREF=gi:4499967 /UG=Hs.42244 Homo sapiens mRNA; cDNA DKFZp564A023 (from clone DKFZp564A023) AL049233 216212_s_at AJ010395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ010395 /DEF=Homo sapiens DKC1 gene, exons 1 to 11 /FEA=CDS /DB_XREF=gi:5542013 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin AJ010395 dyskeratosis congenita 1, dyskerin /// microRNA 664b /// small nucleolar RNA, H/ACA box 56 DKC1 /// MIR664B /// SNORA56 1736 /// 677835 /// 100847052 NM_001142463 /// NM_001288747 /// NM_001363 /// NR_002984 /// NR_049842 /// NR_110021 /// NR_110022 /// NR_110023 0000723 // telomere maintenance // traceable author statement /// 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216213_at AF155113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF155113.1 /DEF=Homo sapiens NY-REN-55 antigen mRNA, partial cds. /FEA=mRNA /PROD=NY-REN-55 antigen /DB_XREF=gi:5360120 /UG=Hs.48332 NIMA (never in mitosis gene a)-related kinase 1 AF155113 NIMA-related kinase 1 NEK1 4750 NM_001199397 /// NM_001199398 /// NM_001199399 /// NM_001199400 /// NM_012224 /// XM_006714227 /// XM_006714228 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000242 // pericentriolar material // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216214_at AF070602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF070602.1 /DEF=Homo sapiens clone 24504 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387982 /UG=Hs.51649 Homo sapiens clone 24504 mRNA sequence AF070602 216215_s_at AL049748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049748 /DEF=Human DNA sequence from clone RP1-41P2 on chromosome 22 Contains the 3 part of the RBM9 gene for RNA binding motif protein 9 and the 3 part of the gene for a novel protein similar to part of APOL (apolipoprotein L) and TNF-inducible protein CG12... /FEA=mRNA_2 /DB_XREF=gi:6572235 /UG=Hs.5011 RNA binding motif protein 9 AL049748 RNA binding protein, fox-1 homolog (C. elegans) 2 RBFOX2 23543 NM_001031695 /// NM_001082576 /// NM_001082577 /// NM_001082578 /// NM_001082579 /// NM_014309 /// XM_005261428 /// XM_005261429 /// XM_005261430 /// XM_005261431 /// XM_005261432 /// XM_005261433 /// XM_005261435 /// XM_005261437 /// XM_006724185 /// XM_006724186 /// XM_006724187 /// XM_006724188 /// XM_006724189 /// XM_006724190 /// XM_006724191 /// XM_006724192 /// XM_006724193 /// XM_006724194 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010724 // regulation of definitive erythrocyte differentiation // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0021942 // radial glia guided migration of Purkinje cell // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 216216_at AL122074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122074.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N0435 (from clone DKFZp434N0435); partial cds. /FEA=mRNA /GEN=DKFZp434N0435 /PROD=hypothetical protein /DB_XREF=gi:6102873 /UG=Hs.57929 slit (Drosophila) homolog 3 AL122074 slit homolog 3 (Drosophila) SLIT3 6586 NM_001271946 /// NM_003062 /// XR_427809 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 0005509 // calcium ion binding // non-traceable author statement /// 0048495 // Roundabout binding // inferred from physical interaction 216217_at AK023546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023546.1 /DEF=Homo sapiens cDNA FLJ13484 fis, clone PLACE1003888, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11). /FEA=mRNA /DB_XREF=gi:10435512 /UG=Hs.54886 phospholipase C, epsilon 2 AK023546 phospholipase C-like 2 PLCL2 23228 NM_001144382 /// NM_015184 /// XM_006713073 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from direct assay 216218_s_at AK023546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023546.1 /DEF=Homo sapiens cDNA FLJ13484 fis, clone PLACE1003888, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11). /FEA=mRNA /DB_XREF=gi:10435512 /UG=Hs.54886 phospholipase C, epsilon 2 AK023546 phospholipase C-like 2 PLCL2 23228 NM_001144382 /// NM_015184 /// XM_006713073 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from direct assay 216219_at AL137716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137716.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D2030 (from clone DKFZp434D2030); partial cds. /FEA=mRNA /GEN=DKFZp434D2030 /PROD=hypothetical protein /DB_XREF=gi:6808132 /UG=Hs.54505 aquaporin 6, kidney specific AL137716 aquaporin 6, kidney specific AQP6 363 NM_001652 /// NM_053286 /// XM_006719375 /// XR_245925 0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015706 // nitrate transport // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from expression pattern /// 0055085 // transmembrane transport // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005253 // anion channel activity // not recorded /// 0015112 // nitrate transmembrane transporter activity // inferred from electronic annotation /// 0015250 // water channel activity // traceable author statement 216220_s_at X68485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68485.1 /DEF=H.sapiens mRNA for A1 adenosine receptor. /FEA=mRNA /PROD=A1 adenosine receptor /DB_XREF=gi:400449 /UG=Hs.77867 adenosine A1 receptor X68485 adenosine A1 receptor ADORA1 134 NM_000674 /// NM_001048230 /// XM_005244899 /// XM_005244901 /// XM_005244902 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0002686 // negative regulation of leukocyte migration // inferred from electronic annotation /// 0002793 // positive regulation of peptide secretion // inferred from electronic annotation /// 0003093 // regulation of glomerular filtration // inferred from electronic annotation /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0006909 // phagocytosis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032244 // positive regulation of nucleoside transport // inferred from electronic annotation /// 0032900 // negative regulation of neurotrophin production // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042323 // negative regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from electronic annotation /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0055117 // regulation of cardiac muscle contraction // inferred from electronic annotation /// 0055118 // negative regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0070256 // negative regulation of mucus secretion // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030673 // axolemma // inferred from electronic annotation /// 0032279 // asymmetric synapse // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0001609 // G-protein coupled adenosine receptor activity // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0001883 // purine nucleoside binding // inferred from electronic annotation /// 0004629 // phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0032795 // heterotrimeric G-protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216221_s_at D87078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87078.2 /DEF=Homo sapiens mRNA for KIAA0235 protein, partial cds. /FEA=mRNA /GEN=KIAA0235 /PROD=KIAA0235 protein /DB_XREF=gi:6634004 /UG=Hs.6151 pumilio (Drosophila) homolog 2 D87078 pumilio RNA-binding family member 2 PUM2 23369 NM_001282752 /// NM_001282790 /// NM_001282791 /// NM_015317 /// XM_005262607 /// XM_005262609 /// XM_005262610 /// XM_006711972 /// XM_006711973 /// XM_006711974 /// XM_006711975 0006417 // regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216222_s_at AI561354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI561354 /FEA=EST /DB_XREF=gi:4511695 /DB_XREF=est:tq48e02.x1 /CLONE=IMAGE:2212058 /UG=Hs.61638 myosin X AI561354 myosin X MYO10 4651 NM_012334 /// XM_005248306 /// XM_005248307 /// XM_006714475 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030705 // cytoskeleton-dependent intracellular transport // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032433 // filopodium tip // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060002 // plus-end directed microfilament motor activity // inferred from sequence or structural similarity 216223_at J05158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J05158.1 /DEF=Human carboxypeptidase N mRNA, 3 end. /FEA=mRNA /GEN=ACBP /DB_XREF=gi:179935 /UG=Hs.73858 carboxypeptidase N, polypeptide 2, 83kD J05158 carboxypeptidase N, polypeptide 2 CPN2 1370 NM_001080513 /// NM_001291988 /// NM_001309 /// XM_005269280 /// XM_005269281 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050821 // protein stabilization // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // non-traceable author statement 216224_s_at AK024083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024083.1 /DEF=Homo sapiens cDNA FLJ14021 fis, clone HEMBA1002513, highly similar to Homo sapiens mRNA for histone deacetylase-like protein (JM21). /FEA=mRNA /DB_XREF=gi:10436372 /UG=Hs.6764 histone deacetylase 6 AK024083 histone deacetylase 6 HDAC6 10013 NM_006044 /// XM_005272564 /// XM_005272565 /// XM_005272566 /// XM_005272568 /// XM_006724525 /// XR_246712 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from mutant phenotype /// 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0010033 // response to organic substance // inferred from mutant phenotype /// 0010469 // regulation of receptor activity // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010727 // negative regulation of hydrogen peroxide metabolic process // inferred by curator /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0032418 // lysosome localization // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0035967 // cellular response to topologically incorrect protein // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0043241 // protein complex disassembly // inferred from electronic annotation /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051354 // negative regulation of oxidoreductase activity // inferred by curator /// 0051788 // response to misfolded protein // inferred from mutant phenotype /// 0060632 // regulation of microtubule-based movement // inferred by curator /// 0060765 // regulation of androgen receptor signaling pathway // traceable author statement /// 0070201 // regulation of establishment of protein localization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from mutant phenotype /// 0070845 // polyubiquitinated misfolded protein transport // inferred from mutant phenotype /// 0070846 // Hsp90 deacetylation // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0071218 // cellular response to misfolded protein // inferred from electronic annotation /// 0090035 // positive regulation of chaperone-mediated protein complex assembly // inferred from mutant phenotype /// 0090042 // tubulin deacetylation // inferred from direct assay /// 0090042 // tubulin deacetylation // inferred from sequence or structural similarity /// 1901300 // positive regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0030286 // dynein complex // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from direct assay /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042903 // tubulin deacetylase activity // inferred from direct assay /// 0042903 // tubulin deacetylase activity // inferred from sequence or structural similarity /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 216225_at R37427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R37427 /FEA=EST /DB_XREF=gi:794883 /DB_XREF=est:yf55g12.s1 /CLONE=IMAGE:25997 /UG=Hs.6524 Homo sapiens clone IMAGE 25997 R37427 216226_at Y09321 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09321.1 /DEF=H.sapiens TAFII105 mRNA, partial. /FEA=mRNA /GEN=TAFII105 /PROD=TBP associated factor /DB_XREF=gi:1669688 /UG=Hs.73083 TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD Y09321 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa TAF4B 6875 NM_001293725 /// NM_005640 /// NR_121653 /// XM_005258339 /// XM_005258340 /// XM_006722528 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction 216227_at X81001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81001.1 /DEF=H.sapiens HCG II mRNA. /FEA=mRNA /DB_XREF=gi:531407 /UG=Hs.69707 HCGII-7 protein X81001 216228_s_at AK001538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001538.1 /DEF=Homo sapiens cDNA FLJ10676 fis, clone NT2RP2006464, highly similar to Homo sapiens mRNA for AND-1 protein. /FEA=mRNA /DB_XREF=gi:7022855 /UG=Hs.72160 AND-1 protein AK001538 WD repeat and HMG-box DNA binding protein 1 WDHD1 11169 NM_001008396 /// NM_007086 /// XM_005267294 /// XM_006720012 0006396 // RNA processing // inferred from electronic annotation /// 0033044 // regulation of chromosome organization // inferred from electronic annotation /// 0070829 // heterochromatin maintenance // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0070063 // RNA polymerase binding // inferred from electronic annotation 216229_x_at X81001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81001.1 /DEF=H.sapiens HCG II mRNA. /FEA=mRNA /DB_XREF=gi:531407 /UG=Hs.69707 HCGII-7 protein X81001 216230_x_at M59917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M59917 /DEF=Human acid sphingomyelinase (ASM) gene, exons a, and alternative a (3 end), b and c (5 end) /FEA=CDS_2 /DB_XREF=gi:179096 /UG=Hs.77813 sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) M59917 sphingomyelin phosphodiesterase 1, acid lysosomal SMPD1 6609 NM_000543 /// NM_001007593 /// NR_027400 /// XM_005253075 0006665 // sphingolipid metabolic process // traceable author statement /// 0006684 // sphingomyelin metabolic process // traceable author statement /// 0006685 // sphingomyelin catabolic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0042599 // lamellar body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 216231_s_at AW188940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188940 /FEA=EST /DB_XREF=gi:6463376 /DB_XREF=est:xk90f09.x1 /CLONE=IMAGE:2674025 /UG=Hs.75415 beta-2-microglobulin AW188940 beta-2-microglobulin B2M 567 NM_004048 /// XM_005254549 /// XM_006725182 0001895 // retina homeostasis // inferred from expression pattern /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042026 // protein refolding // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0031905 // early endosome lumen // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 216232_s_at AI697055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI697055 /FEA=EST /DB_XREF=gi:4984955 /DB_XREF=est:wc85e04.x1 /CLONE=IMAGE:2325438 /UG=Hs.75354 GCN1 (general control of amino-acid synthesis 1, yeast)-like 1 AI697055 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) GCN1L1 10985 NM_006836 0006412 // translation // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 216233_at Z22970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22970.1 /DEF=H.sapiens mRNA for M130 antigen cytoplasmic variant 2. /FEA=mRNA /PROD=M130 antigen cytoplasmic variant 2 /DB_XREF=gi:312145 /UG=Hs.74076 CD163 antigen Z22970 CD163 molecule CD163 9332 NM_004244 /// NM_203416 /// XM_005253528 /// XM_005253529 /// XR_429039 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005044 // scavenger receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 216234_s_at M80335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M80335.1 /DEF=Homo sapiens protein kinase A catalytic subunit mRNA, 3 end. /FEA=mRNA /GEN=KIN27 /PROD=protein kinase A-alpha /DB_XREF=gi:189966 /UG=Hs.77271 protein kinase, cAMP-dependent, catalytic, alpha M80335 protein kinase, cAMP-dependent, catalytic, alpha PRKACA 5566 NM_002730 /// NM_207518 /// XM_005259984 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0002027 // regulation of heart rate // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // traceable author statement /// 0043393 // regulation of protein binding // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from direct assay /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement /// 2000810 // regulation of tight junction assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0034704 // calcium channel complex // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097225 // sperm midpiece // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004691 // cAMP-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from physical interaction 216235_s_at S81545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S81545.1 /DEF=endothelin-A receptor delta 3-4=ET-AR delta 3-4 {alternatively spliced} human, lung, mRNA Partial, 1032 nt. /FEA=mRNA /GEN=endothelin-A receptor delta 3-4 /PROD=endothelin-A receptor delta 3-4 /DB_XREF=gi:1478479 /UG=Hs.76252 endothelin receptor type A S81545 endothelin receptor type A EDNRA 1909 NM_001166055 /// NM_001256283 /// NM_001957 /// NR_045958 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0003094 // glomerular filtration // inferred from electronic annotation /// 0006939 // smooth muscle contraction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from sequence or structural similarity /// 0008152 // metabolic process // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014824 // artery smooth muscle contraction // inferred from mutant phenotype /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0048659 // smooth muscle cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 0090184 // positive regulation of kidney development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 216236_s_at AL110298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110298.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K1672 (from clone DKFZp564K1672); partial cds. /FEA=mRNA /GEN=DKFZp564K1672 /PROD=hypothetical protein /DB_XREF=gi:5817258 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 AL110298 solute carrier family 2 (facilitated glucose transporter), member 14 /// solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A14 /// SLC2A3 6515 /// 144195 NM_001286233 /// NM_001286234 /// NM_001286235 /// NM_001286236 /// NM_001286237 /// NM_006931 /// NM_153449 /// XM_005253315 /// XM_005253317 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 216237_s_at AA807529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA807529 /FEA=EST /DB_XREF=gi:2875596 /DB_XREF=est:ob92c07.s1 /CLONE=IMAGE:1338828 /UG=Hs.77171 minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) AA807529 minichromosome maintenance complex component 5 MCM5 4174 NM_006739 /// XM_006724242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216238_s_at BG545288 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG545288 /FEA=EST /DB_XREF=gi:13543563 /DB_XREF=est:602572504F1 /CLONE=IMAGE:4700592 /UG=Hs.7645 fibrinogen, B beta polypeptide BG545288 fibrinogen beta chain FGB 2244 NM_001184741 /// NM_005141 0002576 // platelet degranulation // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0044320 // cellular response to leptin stimulus // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from direct assay /// 0045921 // positive regulation of exocytosis // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051258 // protein polymerization // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005102 // receptor binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 216239_at U87408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U87408.1 /DEF=Human clone IMAGE:74593 unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1842104 /UG=Hs.79340 PTH-responsive osteosarcoma B1 protein U87408 Bardet-Biedl syndrome 9 BBS9 27241 NM_001033604 /// NM_001033605 /// NM_014451 /// NM_198428 /// XM_005249700 /// XM_005249701 /// XM_006715687 /// XM_006715688 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 216240_at M34428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M34428.1 /DEF=Human transcription unit PVT gene, exons I-III. /FEA=mRNA /DB_XREF=gi:190753 /UG=Hs.8854 Human transcription unit PVT gene, exons I-III M34428 microRNA 1204 /// Pvt1 oncogene (non-protein coding) MIR1204 /// PVT1 5820 /// 100302185 NR_003367 /// NR_031609 216241_s_at X57198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X57198.1 /DEF=Human TFIIS mRNA for transcription elongation factor. /FEA=mRNA /GEN=TFIIS /PROD=transcription elongation factor /DB_XREF=gi:37071 /UG=Hs.78869 transcription elongation factor A (SII), 1 X57198 transcription elongation factor A (SII), 1 TCEA1 6917 NM_006756 /// NM_201437 /// NR_109901 /// NR_109902 /// XM_006716467 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216242_x_at AW402635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW402635 /FEA=EST /DB_XREF=gi:6921341 /DB_XREF=est:UI-HF-BK0-aav-a-09-0-UI.r1 /CLONE=IMAGE:3055001 /UG=Hs.80475 polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) AW402635 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa /// polymerase (RNA) II (DNA directed) polypeptide J2 /// polymerase (RNA) II (DNA directed) polypeptide J3 /// polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene /// uroplakin 3B-like POLR2J /// POLR2J2 /// POLR2J3 /// POLR2J4 /// UPK3BL 5439 /// 84820 /// 246721 /// 548644 /// 100134938 NM_001015884 /// NM_001097615 /// NM_001114403 /// NM_006234 /// NM_032734 /// NM_032958 /// NM_032959 /// NM_145325 /// NR_003655 /// XM_005250452 /// XM_006716032 /// XM_006716033 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 216243_s_at BE563442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE563442 /FEA=EST /DB_XREF=gi:9807162 /DB_XREF=est:601335496F1 /CLONE=IMAGE:3689710 /UG=Hs.81134 interleukin 1 receptor antagonist BE563442 interleukin 1 receptor antagonist IL1RN 3557 NM_000577 /// NM_173841 /// NM_173842 /// NM_173843 /// XM_005263661 /// XM_006712497 0001660 // fever generation // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005150 // interleukin-1, Type I receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // inferred from physical interaction /// 0005152 // interleukin-1 receptor antagonist activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // traceable author statement /// 0045352 // interleukin-1 Type I receptor antagonist activity // inferred from direct assay /// 0045353 // interleukin-1 Type II receptor antagonist activity // inferred from direct assay 216244_at BE563442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE563442 /FEA=EST /DB_XREF=gi:9807162 /DB_XREF=est:601335496F1 /CLONE=IMAGE:3689710 /UG=Hs.81134 interleukin 1 receptor antagonist BE563442 interleukin 1 receptor antagonist IL1RN 3557 NM_000577 /// NM_173841 /// NM_173842 /// NM_173843 /// XM_005263661 /// XM_006712497 0001660 // fever generation // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005150 // interleukin-1, Type I receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // inferred from physical interaction /// 0005152 // interleukin-1 receptor antagonist activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // traceable author statement /// 0045352 // interleukin-1 Type I receptor antagonist activity // inferred from direct assay /// 0045353 // interleukin-1 Type II receptor antagonist activity // inferred from direct assay 216245_at BE563442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE563442 /FEA=EST /DB_XREF=gi:9807162 /DB_XREF=est:601335496F1 /CLONE=IMAGE:3689710 /UG=Hs.81134 interleukin 1 receptor antagonist BE563442 interleukin 1 receptor antagonist IL1RN 3557 NM_000577 /// NM_173841 /// NM_173842 /// NM_173843 /// XM_005263661 /// XM_006712497 0001660 // fever generation // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0002439 // chronic inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006953 // acute-phase response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005149 // interleukin-1 receptor binding // inferred from direct assay /// 0005150 // interleukin-1, Type I receptor binding // inferred from physical interaction /// 0005151 // interleukin-1, Type II receptor binding // inferred from physical interaction /// 0005152 // interleukin-1 receptor antagonist activity // inferred from direct assay /// 0005152 // interleukin-1 receptor antagonist activity // traceable author statement /// 0045352 // interleukin-1 Type I receptor antagonist activity // inferred from direct assay /// 0045353 // interleukin-1 Type II receptor antagonist activity // inferred from direct assay 216246_at AF113008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113008.1 /DEF=Homo sapiens clone FLB0708 mRNA sequence. /FEA=mRNA /DB_XREF=gi:6642739 /UG=Hs.8102 ribosomal protein S20 AF113008 216247_at AF113008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF113008.1 /DEF=Homo sapiens clone FLB0708 mRNA sequence. /FEA=mRNA /DB_XREF=gi:6642739 /UG=Hs.8102 ribosomal protein S20 AF113008 ribosomal protein S20 /// small nucleolar RNA, C/D box 54 RPS20 /// SNORD54 6224 /// 26795 NM_001023 /// NM_001146227 /// NR_002437 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216248_s_at S77154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S77154.1 /DEF=TINUR= NGFI-Bnur77 beta-type transcription factor homolog human, T lymphoid cell line, PEER, mRNA, 2469 nt. /FEA=mRNA /GEN=TINUR /DB_XREF=gi:913966 /UG=Hs.82120 nuclear receptor subfamily 4, group A, member 2 S77154 nuclear receptor subfamily 4, group A, member 2 NR4A2 4929 NM_006186 /// NM_173171 /// NM_173172 /// NM_173173 /// XM_005246621 /// XM_005246622 /// XM_005246623 /// XM_006712553 /// XR_427087 0001666 // response to hypoxia // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016265 // death // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0021986 // habenula development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0031668 // cellular response to extracellular stimulus // inferred from direct assay /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0042053 // regulation of dopamine metabolic process // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051866 // general adaptation syndrome // inferred from electronic annotation /// 0071542 // dopaminergic neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216249_at M34428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M34428.1 /DEF=Human transcription unit PVT gene, exons I-III. /FEA=mRNA /DB_XREF=gi:190753 /UG=Hs.8854 Human transcription unit PVT gene, exons I-III M34428 216250_s_at X77598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X77598.1 /DEF=H.sapiens LAM A3 mRNA for laminin alpha 3 chain. /FEA=mRNA /DB_XREF=gi:9716101 /UG=Hs.83450 laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) X77598 leupaxin LPXN 9404 NM_001143995 /// NM_004811 /// XM_006718750 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from electronic annotation /// 0050859 // negative regulation of B cell receptor signaling pathway // inferred from direct assay 0002102 // podosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216251_s_at BF965437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF965437 /FEA=EST /DB_XREF=gi:12332652 /DB_XREF=est:602268381F1 /CLONE=IMAGE:4356405 /UG=Hs.82563 KIAA0153 protein BF965437 tubulin tyrosine ligase-like family, member 12 TTLL12 23170 NM_015140 0006464 // cellular protein modification process // inferred from electronic annotation 216252_x_at Z70519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z70519.1 /DEF=H.sapiens FASApo 1 mRNA for FAS soluble protein (clone FAS Exo4Del). /FEA=mRNA /PROD=FAS soluble protein /DB_XREF=gi:1418817 /UG=Hs.82359 tumor necrosis factor receptor superfamily, member 6 Z70519 Fas cell surface death receptor FAS 355 NM_000043 /// NM_152871 /// NM_152872 /// NM_152873 /// NM_152874 /// NM_152875 /// NM_152876 /// NM_152877 /// NR_028033 /// NR_028034 /// NR_028035 /// NR_028036 /// XM_006717819 0002377 // immunoglobulin production // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0006925 // inflammatory cell apoptotic process // inferred from electronic annotation /// 0006927 // transformed cell apoptotic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0019724 // B cell mediated immunity // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // non-traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 216253_s_at N73272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N73272 /FEA=EST /DB_XREF=gi:1230376 /DB_XREF=est:za09a05.s1 /CLONE=IMAGE:292016 /UG=Hs.8836 beta-parvin N73272 parvin, beta PARVB 29780 NM_001003828 /// NM_001243385 /// NM_001243386 /// NM_013327 /// XM_005261593 /// XM_005261594 /// XM_005261595 /// XM_005261596 /// XM_006724236 0007155 // cell adhesion // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0071963 // establishment or maintenance of cell polarity regulating cell shape // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216254_at N73272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N73272 /FEA=EST /DB_XREF=gi:1230376 /DB_XREF=est:za09a05.s1 /CLONE=IMAGE:292016 /UG=Hs.8836 beta-parvin N73272 parvin, beta PARVB 29780 NM_001003828 /// NM_001243385 /// NM_001243386 /// NM_013327 /// XM_005261593 /// XM_005261594 /// XM_005261595 /// XM_005261596 /// XM_006724236 0007155 // cell adhesion // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0071963 // establishment or maintenance of cell polarity regulating cell shape // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216255_s_at AC000099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC000099 /DEF=Cosmid g0771a003 /FEA=CDS /DB_XREF=gi:1764159 /UG=Hs.86204 glutamate receptor, metabotropic 8 AC000099 glutamate receptor, metabotropic 8 GRM8 2918 NM_000845 /// NM_001127323 /// NR_028041 /// XM_006715938 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007601 // visual perception // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0008066 // glutamate receptor activity // inferred from mutant phenotype 216256_at AC000099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC000099 /DEF=Cosmid g0771a003 /FEA=CDS /DB_XREF=gi:1764159 /UG=Hs.86204 glutamate receptor, metabotropic 8 AC000099 glutamate receptor, metabotropic 8 GRM8 2918 NM_000845 /// NM_001127323 /// NR_028041 /// XM_006715938 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007601 // visual perception // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0008066 // glutamate receptor activity // inferred from mutant phenotype 216257_at BE148534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE148534 /FEA=EST /DB_XREF=gi:8611258 /DB_XREF=est:MR0-HT0241-030200-008-h03 /UG=Hs.84168 UV-B repressed sequence, HUR 7 BE148534 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 216258_s_at BE148534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE148534 /FEA=EST /DB_XREF=gi:8611258 /DB_XREF=est:MR0-HT0241-030200-008-h03 /UG=Hs.84168 UV-B repressed sequence, HUR 7 BE148534 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 216259_at U85992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U85992.1 /DEF=Human clone IMAGE:35527 unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1835745 /UG=Hs.87197 Human clone IMAGE:35527 unknown protein mRNA, partial cds U85992 uncharacterized LOC100506699 LOC100506699 100506699 XM_003118571 /// XM_003119029 /// XM_003120027 216260_at AK001827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001827.1 /DEF=Homo sapiens cDNA FLJ10965 fis, clone PLACE1000755, highly similar to Homo sapiens mRNA for Helicase-MOI. /FEA=mRNA /DB_XREF=gi:7023337 /UG=Hs.87889 helicase-moi AK001827 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216261_at AI151479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI151479 /FEA=EST /DB_XREF=gi:3679948 /DB_XREF=est:qc74g06.x1 /CLONE=IMAGE:1715386 /UG=Hs.87149 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) AI151479 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 3690 NM_000212 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006457 // protein folding // inferred from direct assay /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0035295 // tube development // traceable author statement /// 0042060 // wound healing // inferred by curator /// 0045124 // regulation of bone resorption // traceable author statement /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 216262_s_at AL050318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050318 /DEF=Human DNA sequence from clone RP5-977B1 on chromosome 20 Contains ESTs, STSs, GSSs and three putative CpG islands. Contains the 3 end of the gene for a novel protein tyrosine kinase with Src homology domain 2 domains, a heterogeneous nuclear ribo... /FEA=mRNA_5 /DB_XREF=gi:9581785 /UG=Hs.94785 TGF(beta)-induced transcription factor 2 AL050318 TGFB-induced factor homeobox 2 TGIF2 60436 NM_001199513 /// NM_001199514 /// NM_001199515 /// NM_021809 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216263_s_at AK022215 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022215.1 /DEF=Homo sapiens cDNA FLJ12153 fis, clone MAMMA1000458. /FEA=mRNA /DB_XREF=gi:10433563 /UG=Hs.9043 DKFZP564O092 protein AK022215 neuroguidin, EIF4E binding protein NGDN 25983 NM_001042635 /// NM_015514 0006417 // regulation of translation // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 216264_s_at X79683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79683.1 /DEF=H.sapiens LAMB2 mRNA for beta2 laminin. /FEA=mRNA /GEN=LAMB2 /PROD=beta2S laminin chain /DB_XREF=gi:663206 /UG=Hs.90291 laminin, beta 2 (laminin S) X79683 laminin, beta 2 (laminin S) LAMB2 3913 NM_002292 /// XM_005265127 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048677 // axon extension involved in regeneration // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0072249 // metanephric glomerular visceral epithelial cell development // inferred from electronic annotation /// 0072274 // metanephric glomerular basement membrane development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005608 // laminin-3 complex // inferred from physical interaction /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043256 // laminin complex // inferred from electronic annotation /// 0043260 // laminin-11 complex // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216265_x_at AI292276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI292276 /FEA=EST /DB_XREF=gi:3935050 /DB_XREF=est:qm76d10.x1 /CLONE=IMAGE:1894675 /UG=Hs.929 myosin, heavy polypeptide 7, cardiac muscle, beta AI292276 myosin, heavy chain 7, cardiac muscle, beta MYH7 4625 NM_000257 /// XM_005267696 /// XM_005267697 /// XR_245686 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from direct assay /// 0002027 // regulation of heart rate // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006936 // muscle contraction // inferred from direct assay /// 0006936 // muscle contraction // traceable author statement /// 0006941 // striated muscle contraction // inferred from direct assay /// 0007512 // adult heart development // inferred from mutant phenotype /// 0007522 // visceral muscle development // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from mutant phenotype /// 0030239 // myofibril assembly // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0043462 // regulation of ATPase activity // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0048739 // cardiac muscle fiber development // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060420 // regulation of heart growth // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005859 // muscle myosin complex // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016459 // myosin complex // traceable author statement /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0032982 // myosin filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from mutant phenotype 216266_s_at AK025637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025637.1 /DEF=Homo sapiens cDNA: FLJ21984 fis, clone HEP06222, highly similar to AF111162 Homo sapiens guanine nucleotide exchange factor mRNA. /FEA=mRNA /DB_XREF=gi:10438216 /UG=Hs.94631 brefeldin A-inhibited guanine nucleotide-exchange protein 1 AK025637 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) ARFGEF1 10565 NM_006421 /// XM_005251134 /// XM_005251135 /// XM_005251136 /// XM_006716418 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030837 // negative regulation of actin filament polymerization // inferred from mutant phenotype /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0090284 // positive regulation of protein glycosylation in Golgi // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay 216267_s_at BF034906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF034906 /FEA=EST /DB_XREF=gi:10742618 /DB_XREF=est:601458947F1 /CLONE=IMAGE:3862474 /UG=Hs.91566 PL6 protein BF034906 transmembrane protein 115 TMEM115 11070 NM_007024 0008285 // negative regulation of cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216268_s_at U77914 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U77914.1 /DEF=Human soluble protein Jagged mRNA, partial cds. /FEA=mRNA /PROD=soluble protein Jagged /DB_XREF=gi:1684889 /UG=Hs.91143 jagged 1 (Alagille syndrome) U77914 jagged 1 JAG1 182 NM_000214 0001525 // angiogenesis // non-traceable author statement /// 0001709 // cell fate determination // non-traceable author statement /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0030097 // hemopoiesis // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0030334 // regulation of cell migration // non-traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // non-traceable author statement /// 0045446 // endothelial cell differentiation // non-traceable author statement /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045639 // positive regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from mutant phenotype /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0061314 // Notch signaling involved in heart development // inferred from mutant phenotype /// 0061444 // endocardial cushion cell development // inferred from sequence or structural similarity /// 0072017 // distal tubule development // inferred from electronic annotation /// 0072070 // loop of Henle development // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005112 // Notch binding // non-traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // non-traceable author statement 216269_s_at M24782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M24782.1 /DEF=Homo sapiens elastin (ELN) mRNA, 3 end. /FEA=CDS /GEN=ELN /PROD=elastin /DB_XREF=gi:182063 /UG=Hs.9295 elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) M24782 elastin ELN 2006 NM_000501 /// NM_001081752 /// NM_001081753 /// NM_001081754 /// NM_001081755 /// NM_001278912 /// NM_001278913 /// NM_001278914 /// NM_001278915 /// NM_001278916 /// NM_001278917 /// NM_001278918 /// NM_001278939 /// XM_005250187 /// XM_005250188 /// XM_006715874 /// XM_006715875 /// XM_006715876 /// XM_006715877 /// XM_006715878 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0071953 // elastic fiber // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 216270_at AF209931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF209931.1 /DEF=Homo sapiens 7h3 protein mRNA, partial cds. /FEA=mRNA /PROD=7h3 protein /DB_XREF=gi:6653741 /UG=Hs.9291 Homo sapiens cDNA FLJ13511 fis, clone PLACE1005331, highly similar to Homo sapiens 7h3 protein mRNA AF209931 ilvB (bacterial acetolactate synthase)-like ILVBL 10994 NM_006844 /// NM_176826 /// XM_005259717 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216271_x_at AC004794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004794 /DEF=Homo sapiens chromosome 19, cosmid F20569 /FEA=CDS_3 /DB_XREF=gi:3184261 /UG=Hs.9291 Homo sapiens cDNA FLJ13511 fis, clone PLACE1005331, highly similar to Homo sapiens 7h3 protein mRNA AC004794 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) SYDE1 85360 NM_033025 /// XM_005260126 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032862 // activation of Rho GTPase activity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity 216272_x_at AF209931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF209931.1 /DEF=Homo sapiens 7h3 protein mRNA, partial cds. /FEA=mRNA /PROD=7h3 protein /DB_XREF=gi:6653741 /UG=Hs.9291 Homo sapiens cDNA FLJ13511 fis, clone PLACE1005331, highly similar to Homo sapiens 7h3 protein mRNA AF209931 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) SYDE1 85360 NM_033025 /// XM_005260126 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032862 // activation of Rho GTPase activity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity 216273_at X78931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X78931.1 /DEF=H.sapiens HZF8 mRNA for zinc finger protein. /FEA=mRNA /GEN=HZF8 /PROD=zinc finger protein /DB_XREF=gi:498733 /UG=Hs.99971 zinc finger protein 272 X78931 zinc finger protein 460 ZNF460 10794 NM_006635 /// XM_005258422 /// XM_006722976 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216274_s_at N99438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N99438 /FEA=EST /DB_XREF=gi:1270864 /DB_XREF=est:yz96c06.r1 /CLONE=IMAGE:290890 /UG=Hs.9534 signal peptidase complex (18kD) N99438 SEC11 homolog A (S. cerevisiae) SEC11A 23478 NM_001271918 /// NM_001271919 /// NM_001271920 /// NM_001271921 /// NM_001271922 /// NM_014300 /// NR_073518 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216275_at AK023540 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023540.1 /DEF=Homo sapiens cDNA FLJ13478 fis, clone PLACE1003709, highly similar to Homo sapiens mitotic checkpoint kinase Bub1 (BUB1) mRNA. /FEA=mRNA /DB_XREF=gi:10435502 /UG=Hs.98658 budding uninhibited by benzimidazoles 1 (yeast homolog) AK023540 BUB1 mitotic checkpoint serine/threonine kinase BUB1 699 NM_001278616 /// NM_001278617 /// NM_004336 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007063 // regulation of sister chromatid cohesion // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype /// 0071173 // spindle assembly checkpoint // inferred from direct assay /// 0071173 // spindle assembly checkpoint // inferred from mutant phenotype /// 0071174 // mitotic spindle checkpoint // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216276_s_at X89657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89657.1 /DEF=H.sapiens mRNA for cyritestin protein (clone T6). /FEA=mRNA /DB_XREF=gi:3059115 /UG=Hs.98848 a disintegrin and metalloproteinase domain 3a (cyritestin 1) X89657 ADAM metallopeptidase domain 3A (pseudogene) ADAM3A 1587 NR_001569 /// NR_024106 /// NR_024107 /// NR_073423 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation 216277_at AU156551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU156551 /FEA=EST /DB_XREF=gi:11018072 /DB_XREF=est:AU156551 /CLONE=PLACE1003709 /UG=Hs.98658 budding uninhibited by benzimidazoles 1 (yeast homolog) AU156551 BUB1 mitotic checkpoint serine/threonine kinase BUB1 699 NM_001278616 /// NM_001278617 /// NM_004336 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007063 // regulation of sister chromatid cohesion // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype /// 0071173 // spindle assembly checkpoint // inferred from direct assay /// 0071173 // spindle assembly checkpoint // inferred from mutant phenotype /// 0071174 // mitotic spindle checkpoint // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216278_at AL109705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109705.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 73337. /FEA=mRNA /DB_XREF=gi:5689834 /UG=Hs.9997 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 73337 AL109705 216279_at X78931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X78931.1 /DEF=H.sapiens HZF8 mRNA for zinc finger protein. /FEA=mRNA /GEN=HZF8 /PROD=zinc finger protein /DB_XREF=gi:498733 /UG=Hs.99971 zinc finger protein 272 X78931 zinc finger protein 460 ZNF460 10794 NM_006635 /// XM_005258422 /// XM_006722976 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216280_s_at AK001827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001827.1 /DEF=Homo sapiens cDNA FLJ10965 fis, clone PLACE1000755, highly similar to Homo sapiens mRNA for Helicase-MOI. /FEA=mRNA /DB_XREF=gi:7023337 /UG=Hs.87889 helicase-moi AK001827 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216281_at AK001827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001827.1 /DEF=Homo sapiens cDNA FLJ10965 fis, clone PLACE1000755, highly similar to Homo sapiens mRNA for Helicase-MOI. /FEA=mRNA /DB_XREF=gi:7023337 /UG=Hs.87889 helicase-moi AK001827 dicer 1, ribonuclease type III DICER1 23405 NM_001195573 /// NM_001271282 /// NM_001291628 /// NM_030621 /// NM_177438 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010626 // negative regulation of Schwann cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014040 // positive regulation of Schwann cell differentiation // inferred from sequence or structural similarity /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032290 // peripheral nervous system myelin formation // inferred from sequence or structural similarity /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0070173 // regulation of enamel mineralization // inferred from electronic annotation /// 0071335 // hair follicle cell proliferation // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000630 // positive regulation of miRNA metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216282_x_at AJ224143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ224143.1 /DEF=Homo sapiens mRNA variant alfa for RNA polymerase II subunit 3. /FEA=mRNA /GEN=RPB3 /PROD=RNA polymerase II subunit /DB_XREF=gi:2920708 /UG=Hs.79402 polymerase (RNA) II (DNA directed) polypeptide C (33kD) AJ224143 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa POLR2C 5432 NM_002694 /// NM_032940 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 216283_s_at X64116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X64116 /DEF=H.sapiens PVR gene for poliovirus receptor (exon 1) /FEA=CDS_3 /DB_XREF=gi:35809 /UG=Hs.321018 poliovirus receptor X64116 poliovirus receptor PVR 5817 NM_001135768 /// NM_001135769 /// NM_001135770 /// NM_006505 /// XM_005259120 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 216284_at AK024123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024123.1 /DEF=Homo sapiens cDNA FLJ14061 fis, clone HEMBB1000749. /FEA=mRNA /DB_XREF=gi:10436427 /UG=Hs.306664 Homo sapiens cDNA FLJ14061 fis, clone HEMBB1000749 AK024123 216285_at AL137713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137713.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I0523 (from clone DKFZp434I0523). /FEA=mRNA /DB_XREF=gi:6808127 /UG=Hs.306465 Homo sapiens mRNA; cDNA DKFZp434I0523 (from clone DKFZp434I0523) AL137713 DiGeorge syndrome critical region gene 14 /// testis-specific serine kinase 2 DGCR14 /// TSSK2 8220 /// 23617 NM_022719 /// NM_053006 /// XM_005261282 /// XM_006724329 /// XM_006724330 /// XM_006724331 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216286_at AV760769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV760769 /FEA=EST /DB_XREF=gi:10918617 /DB_XREF=est:AV760769 /CLONE=MDSBSE09 /UG=Hs.306324 Homo sapiens mRNA; cDNA DKFZp434G182 (from clone DKFZp434G182) AV760769 216287_at AK021930 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021930.1 /DEF=Homo sapiens cDNA FLJ11868 fis, clone HEMBA1006993. /FEA=mRNA /DB_XREF=gi:10433231 /UG=Hs.302260 Homo sapiens cDNA FLJ11868 fis, clone HEMBA1006993 AK021930 216288_at AU159276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU159276 /FEA=EST /DB_XREF=gi:11020797 /DB_XREF=est:AU159276 /CLONE=THYRO1001262 /UG=Hs.301150 Homo sapiens cDNA FLJ13867 fis, clone THYRO1001262 AU159276 cysteinyl leukotriene receptor 1 CYSLTR1 10800 NM_001282186 /// NM_001282187 /// NM_001282188 /// NM_006639 0006816 // calcium ion transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216289_at AU148039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU148039 /FEA=EST /DB_XREF=gi:11009560 /DB_XREF=est:AU148039 /CLONE=MAMMA1002427 /UG=Hs.296719 Homo sapiens cDNA FLJ12369 fis, clone MAMMA1002427 AU148039 G protein-coupled receptor 144 GPR144 347088 NM_001161808 /// NM_182611 /// XM_006710216 /// XM_006717348 /// XM_006726503 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 216290_x_at AK000864 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000864.1 /DEF=Homo sapiens cDNA FLJ10002 fis, clone HEMBA1000046. /FEA=mRNA /DB_XREF=gi:7021188 /UG=Hs.296522 Homo sapiens cDNA FLJ10002 fis, clone HEMBA1000046 AK000864 216291_at AK021474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021474.1 /DEF=Homo sapiens cDNA FLJ11412 fis, clone HEMBA1000876. /FEA=mRNA /DB_XREF=gi:10432666 /UG=Hs.289094 Homo sapiens cDNA FLJ11412 fis, clone HEMBA1000876 AK021474 zinc finger protein 440 ZNF440 126070 NM_152357 /// XM_005259731 /// XM_006722641 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216292_at AK024455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024455.1 /DEF=Homo sapiens mRNA for FLJ00047 protein, partial cds. /FEA=mRNA /GEN=FLJ00047 /PROD=FLJ00047 protein /DB_XREF=gi:10440423 /UG=Hs.287753 Homo sapiens mRNA for FLJ00047 protein, partial cds AK024455 216293_at X81636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81636.1 /DEF=H.sapiens clathrin light chain a gene. /FEA=mRNA /DB_XREF=gi:704460 /UG=Hs.285688 H.sapiens clathrin light chain a gene X81636 clathrin, light chain A CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 216294_s_at AL137254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137254.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B1113 (from clone DKFZp434B1113); partial cds. /FEA=mRNA /GEN=DKFZp434B1113 /PROD=hypothetical protein /DB_XREF=gi:6807676 /UG=Hs.6606 KIAA1109 protein AL137254 KIAA1109 KIAA1109 84162 NM_015312 /// NM_032202 /// XM_005263282 /// XM_005263283 /// XM_005263284 /// XM_005263285 /// XM_005263286 /// XM_005263287 /// XM_005263288 /// XM_005263289 /// XM_005263290 /// XM_005263291 /// XM_005263292 /// XM_006714342 /// XM_006714343 /// XM_006714344 0001558 // regulation of cell growth // non-traceable author statement /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 216295_s_at X81636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81636.1 /DEF=H.sapiens clathrin light chain a gene. /FEA=mRNA /DB_XREF=gi:704460 /UG=Hs.285688 H.sapiens clathrin light chain a gene X81636 clathrin, light chain A CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 216296_at X81636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81636.1 /DEF=H.sapiens clathrin light chain a gene. /FEA=mRNA /DB_XREF=gi:704460 /UG=Hs.285688 H.sapiens clathrin light chain a gene X81636 clathrin, light chain A CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 216297_at AL049314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049314.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C156 (from clone DKFZp564C156). /FEA=mRNA /DB_XREF=gi:4500088 /UG=Hs.278592 Homo sapiens mRNA; cDNA DKFZp564C156 (from clone DKFZp564C156) AL049314 RP11-348N5.7 216298_at AL580863 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL580863 /FEA=EST /DB_XREF=gi:12947295 /DB_XREF=est:AL580863 /CLONE=CS0DJ012YJ02 (3 prime) /UG=Hs.274509 T cell receptor gamma constant 2 AL580863 TCR gamma alternate reading frame protein TARP 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 216299_s_at AK022829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022829.1 /DEF=Homo sapiens cDNA FLJ12767 fis, clone NT2RP2001536, highly similar to Homo sapiens X-ray repair cross-complementing protein 3 (XRCC3) mRNA. /FEA=mRNA /DB_XREF=gi:10434452 /UG=Hs.99742 X-ray repair complementing defective repair in Chinese hamster cells 3 AK022829 X-ray repair complementing defective repair in Chinese hamster cells 3 XRCC3 7517 NM_001100118 /// NM_001100119 /// NM_005432 /// XM_005268046 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006310 // DNA recombination // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0071140 // resolution of mitotic recombination intermediates // inferred from mutant phenotype /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0033065 // Rad51C-XRCC3 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from mutant phenotype 216300_x_at BE383139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE383139 /FEA=EST /DB_XREF=gi:9328504 /DB_XREF=est:601297175F1 /CLONE=IMAGE:3627259 /UG=Hs.250505 retinoic acid receptor, alpha BE383139 retinoic acid receptor, alpha RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay 216301_at AW405975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW405975 /FEA=EST /DB_XREF=gi:6925032 /DB_XREF=est:UI-HF-BL0-acv-a-05-0-UI.r1 /CLONE=IMAGE:3060368 /UG=Hs.247721 Homo sapiens clone mcg53-54 immunoglobulin lambda light chain variable region 4a mRNA, partial cds AW405975 216302_at AL022101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022101 /DEF=Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contain... /FEA=mRNA_2 /DB_XREF=gi:3171895 /UG=Hs.239530 Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contains ESTs, AL022101 heterogeneous nuclear ribonucleoprotein C-like 1 /// heterogeneous nuclear ribonucleoprotein C-like 2 /// heterogeneous nuclear ribonucleoprotein C-like 1-like /// heterogeneous nuclear ribonucleoprotein C-like HNRNPCL1 /// HNRNPCL2 /// LOC101060301 /// LOC649330 343069 /// 440563 /// 649330 /// 101060301 NM_001013631 /// NM_001136561 /// NM_001146181 /// XM_003960114 /// XM_006711084 /// XM_006724957 0005634 // nucleus // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216303_s_at AK023451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023451.1 /DEF=Homo sapiens cDNA FLJ13389 fis, clone PLACE1001171, moderately similar to MYOTUBULARIN. /FEA=mRNA /DB_XREF=gi:10435390 /UG=Hs.204920 Homo sapiens cDNA FLJ13389 fis, clone PLACE1001171, moderately similar to MYOTUBULARIN AK023451 myotubularin related protein 1 MTMR1 8776 NM_003828 /// NM_176789 /// XM_005274765 /// XM_005274766 /// XM_005274767 /// XM_005274768 /// XM_006724854 /// XM_006724855 /// XM_006724856 /// XR_247319 /// XR_430557 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from sequence or structural similarity /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 216304_x_at AJ295618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ295618 /DEF=Homo sapiens FTSH gene for putative ATPases, exons 1 and 2 and join CDS /FEA=mRNA /DB_XREF=gi:9506352 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 AJ295618 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216305_s_at AC005034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005034 /DEF=Homo sapiens BAC clone RP11-342K6 from 2 /FEA=CDS_1 /DB_XREF=gi:3947437 /UG=Hs.184175 chromosome 2 open reading frame 3 AC005034 GC-rich sequence DNA-binding factor 2 GCFC2 6936 NM_001201334 /// NM_001201335 /// NM_003203 /// XM_005264520 /// XM_005264521 /// XR_426995 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 216306_x_at X62006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X62006.1 /DEF=H.sapiens PTB-1 gene for polypirimidine tract binding protein. /FEA=mRNA /GEN=PTB-1 /PROD=polypirimidine tract binding protein /DB_XREF=gi:35767 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) X62006 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 216307_at AB018261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018261.1 /DEF=Homo sapiens mRNA for KIAA0718 protein, partial cds. /FEA=mRNA /GEN=KIAA0718 /PROD=KIAA0718 protein /DB_XREF=gi:3882156 /UG=Hs.158318 diacylglycerol kinase, beta (90kD) AB018261 diacylglycerol kinase, beta 90kDa DGKB 1607 NM_004080 /// NM_145695 /// XM_005249628 /// XM_005249629 /// XM_005249630 /// XM_005249631 /// XR_428070 /// XR_428071 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216308_x_at AK026752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026752.1 /DEF=Homo sapiens cDNA: FLJ23099 fis, clone LNG07460, highly similar to AF113251 Homo sapiens putative 2-hydroxyacid dehydrogenase mRNA. /FEA=mRNA /DB_XREF=gi:10439675 /UG=Hs.155742 glyoxylate reductasehydroxypyruvate reductase AK026752 glyoxylate reductase/hydroxypyruvate reductase GRHPR 9380 NM_012203 /// XM_005251631 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007588 // excretion // inferred from mutant phenotype /// 0008152 // metabolic process // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043648 // dicarboxylic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0008465 // glycerate dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016618 // hydroxypyruvate reductase activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay 216309_x_at AF072467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072467.1 /DEF=Homo sapiens (JH8) mRNA, partial cds. /FEA=mRNA /GEN=JH8 /PROD=unknown /DB_XREF=gi:3435200 /UG=Hs.142296 jerky (mouse) homolog AF072467 Jrk homolog (mouse) JRK 8629 NM_001077527 /// NM_001279352 /// NM_003724 /// XM_006716677 /// XM_006716678 /// XM_006716679 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216310_at AK024376 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024376.1 /DEF=Homo sapiens cDNA FLJ14314 fis, clone PLACE3000350, weakly similar to SERINETHREONINE-PROTEIN KINASE SULU (EC 2.7.1.-). /FEA=mRNA /DB_XREF=gi:10436747 /UG=Hs.15119 KIAA1361 protein AK024376 TAO kinase 1 TAOK1 57551 NM_020791 /// NM_025142 0000165 // MAPK cascade // not recorded /// 0000186 // activation of MAPKK activity // not recorded /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from direct assay /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016301 // kinase activity // non-traceable author statement /// 0016740 // transferase activity // non-traceable author statement /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216311_at AI206718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI206718 /FEA=EST /DB_XREF=gi:3765390 /DB_XREF=est:qf61b12.x1 /CLONE=IMAGE:1754495 /UG=Hs.143920 Homo sapiens DNA from chromosome 19-cosmid f24590 containing CAPNS and POL2RI, genomic sequence AI206718 ovo-like zinc finger 3 OVOL3 728361 NM_001270948 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216312_at AW615612 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW615612 /FEA=EST /DB_XREF=gi:7316310 /DB_XREF=est:ba12g08.x1 /CLONE=IMAGE:2824190 /UG=Hs.103124 ATPase, Ca++ transporting, plasma membrane 3 AW615612 ATPase, Ca++ transporting, plasma membrane 3 ATP2B3 492 NM_001001344 /// NM_021949 /// XM_005274689 /// XM_005274690 /// XM_005274691 /// XM_005274692 /// XM_005274693 /// XM_006724823 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005388 // calcium-transporting ATPase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216313_at AF152527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152527.1 /DEF=Homo sapiens PCDH-psi1 pseudogene, mRNA sequence. /FEA=mRNA /DB_XREF=gi:5457101 /UG=Hs.284307 protocadherin beta 17 pseudogene AF152527 protocadherin beta 17 pseudogene PCDHB17 54661 NR_001280 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 216314_at X95238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95238.1 /DEF=H.sapiens mRNA for cysteine-rich secretory protein-1 delta. /FEA=mRNA /GEN=CRISP-1delta /PROD=cysteine-rich secretory protein-1 delta /DB_XREF=gi:1262812 /UG=Hs.109620 acidic epididymal glycoprotein-like 1 X95238 cysteine-rich secretory protein 1 CRISP1 167 NM_001131 /// NM_001205220 /// NM_170609 /// XM_006715003 0007342 // fusion of sperm to egg plasma membrane // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay 216315_x_at AL121873 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121873 /DEF=Human DNA sequence from clone RP13-362E11 on chromosome X. Contains a pseudogene similar to mouse GEG-154 and mosquito MRRG, a pseudogene similar to human MMS2 and chicken CROC-1B, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:8218071 /UG=Hs.283845 Human DNA sequence from clone RP13-362E11 on chromosome X. Contains a pseudogene similar to mouse GEG-154 and mosquito MRRG, a pseudogene similar to human MMS2 and chicken CROC-1B, ESTs, STSs and GSSs AL121873 ubiquitin-conjugating enzyme E2 variant 1 pseudogene 9 /// UBE2V1P9 /// UBE2V1P9 216316_x_at X78713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X78713 /DEF=H.sapiens glycerol kinase pseudogene, chromosome 1 /FEA=CDS /DB_XREF=gi:515027 /UG=Hs.282272 glycerol kinase pseudogene 1 X78713 RP11-548H18.2 216317_x_at X63095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63095.1 /DEF=H.sapiens mRNA for rhesus polypeptide (RhVI). /FEA=mRNA /PROD=Rhesus polypeptide RhVI /DB_XREF=gi:36042 /UG=Hs.278994 Rhesus blood group, CcEe antigens X63095 Rh blood group, CcEe antigens /// Rh blood group, D antigen RHCE /// RHD 6006 /// 6007 NM_001127691 /// NM_001282867 /// NM_001282868 /// NM_001282869 /// NM_001282870 /// NM_001282871 /// NM_001282872 /// NM_016124 /// NM_016225 /// NM_020485 /// NM_138616 /// NM_138617 /// NM_138618 /// XM_005245957 /// XM_006710810 0015696 // ammonium transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008519 // ammonium transmembrane transporter activity // inferred from electronic annotation 216318_at S55735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S55735.1 /DEF=Homo sapiens immunoglobulin A1-A2 lambda hybrid GAU heavy chain mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin A1-A2 lambda hybrid GAU heavychain /DB_XREF=gi:265703 /UG=Hs.293441 VPS28 protein S55735 216319_at AK022686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022686.1 /DEF=Homo sapiens cDNA FLJ12624 fis, clone NT2RM4001754. /FEA=mRNA /DB_XREF=gi:10434225 /UG=Hs.306639 Homo sapiens cDNA FLJ12624 fis, clone NT2RM4001754 AK022686 RP11-69I8.2 216320_x_at U37055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U37055 /DEF=Human hepatocyte growth factor-like protein gene, complete cds /FEA=mRNA /DB_XREF=gi:1311660 /UG=Hs.278657 macrophage stimulating 1 (hepatocyte growth factor-like) U37055 macrophage stimulating 1 (hepatocyte growth factor-like) MST1 4485 NM_020998 /// XM_006713166 /// XM_006713167 /// XM_006713168 /// XM_006713169 /// XR_427269 /// XR_427270 /// XR_427271 /// XR_427272 /// XR_427273 /// XR_427274 /// XR_427275 /// XR_427276 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216321_s_at X03348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X03348.1 /DEF=Human mRNA for beta-glucocorticoid receptor (clone OB10). /FEA=mRNA /PROD=beta-glucocorticoid receptor /DB_XREF=gi:31681 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 X03348 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 216322_at D28586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D28586.1 /DEF=Human mRNA for LFA-3(delta D2), partial cds. /FEA=mRNA /PROD=LFA-3(delta D2) /DB_XREF=gi:466540 /UG=Hs.75626 CD58 antigen, (lymphocyte function-associated antigen 3) D28586 CD58 molecule CD58 965 NM_001144822 /// NM_001779 /// NR_026665 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 216323_x_at K03460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K03460 /DEF=Human alpha-tubulin isotype H2-alpha gene, last exon /FEA=CDS /DB_XREF=gi:340016 /UG=Hs.75318 tubulin, alpha 1 (testis specific) K03460 tubulin, alpha 3c /// tubulin, alpha 3d TUBA3C /// TUBA3D 7278 /// 113457 NM_006001 /// NM_079836 /// NM_080386 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 216324_at Z21967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z21967.1 /DEF=H.sapiens partial cDNA for homologue of mPOU homeobox protein. /FEA=mRNA /PROD=mPOU homeobox protein /DB_XREF=gi:437875 /UG=Hs.2815 POU domain, class 6, transcription factor 1 Z21967 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216325_x_at AF217796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF217796 /DEF=Homo sapiens SCG10 like-protein, helicase-like protein NHL, M68, and ADP-ribosylation factor related protein 1 (ARFRP1) genes, complete cds /FEA=CDS_1 /DB_XREF=gi:7012928 /UG=Hs.281383 helicase-like protein NHL AF217796 regulator of telomere elongation helicase 1 /// RTEL1-TNFRSF6B readthrough (NMD candidate) RTEL1 /// RTEL1-TNFRSF6B 51750 /// 100533107 NM_001283009 /// NM_001283010 /// NM_016434 /// NM_032957 /// NR_037882 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from sequence or structural similarity /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 216326_s_at AF059650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF059650 /DEF=Homo sapiens histone deacetylase 3 (HDAC3) gene, complete cds /FEA=mRNA /DB_XREF=gi:3320449 /UG=Hs.279789 histone deacetylase 3 AF059650 histone deacetylase 3 HDAC3 8841 NM_003883 /// XM_006714802 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0004407 // histone deacetylase activity // inferred from mutant phenotype /// 0004407 // histone deacetylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from physical interaction /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 216327_s_at AF287892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF287892 /DEF=Homo sapiens sialic acid binding immunoglobulin-like lectin 8 long splice variant (Siglec8) gene, complete cds /FEA=mRNA /DB_XREF=gi:9837432 /UG=Hs.279751 sialic acid binding Ig-like lectin 8 AF287892 sialic acid binding Ig-like lectin 8 SIGLEC8 27181 NM_014442 /// XR_243922 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement 216328_at AF287892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF287892 /DEF=Homo sapiens sialic acid binding immunoglobulin-like lectin 8 long splice variant (Siglec8) gene, complete cds /FEA=mRNA /DB_XREF=gi:9837432 /UG=Hs.279751 sialic acid binding Ig-like lectin 8 AF287892 sialic acid binding Ig-like lectin 8 SIGLEC8 27181 NM_014442 /// XR_243922 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // traceable author statement 216329_at Z21967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z21967.1 /DEF=H.sapiens partial cDNA for homologue of mPOU homeobox protein. /FEA=mRNA /PROD=mPOU homeobox protein /DB_XREF=gi:437875 /UG=Hs.2815 POU domain, class 6, transcription factor 1 Z21967 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216330_s_at L14482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L14482.1 /DEF=Homo sapiens transcription factor 7 (TCFB) mRNA sequence. /FEA=mRNA /DB_XREF=gi:292735 /UG=Hs.2815 POU domain, class 6, transcription factor 1 L14482 POU class 6 homeobox 1 POU6F1 5463 NM_002702 /// NR_026893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216331_at AK022548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022548.1 /DEF=Homo sapiens cDNA FLJ12486 fis, clone NT2RM2000566, highly similar to Homo sapiens integrin alpha-7 mRNA. /FEA=mRNA /DB_XREF=gi:10434001 /UG=Hs.74369 integrin, alpha 7 AK022548 integrin, alpha 7 ITGA7 3679 NM_001144996 /// NM_001144997 /// NM_002206 /// XM_005268839 /// XM_005268840 /// XM_005268841 /// XM_005268842 /// XM_005268844 /// XM_005268845 /// XM_005268846 /// XM_005268847 /// XM_005268848 /// XM_005268849 /// XM_005268850 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0034677 // integrin alpha7-beta1 complex // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 216332_at L14482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L14482.1 /DEF=Homo sapiens transcription factor 7 (TCFB) mRNA sequence. /FEA=mRNA /DB_XREF=gi:292735 /UG=Hs.2815 POU domain, class 6, transcription factor 1 L14482 POU class 6 homeobox 1 POU6F1 5463 NM_002702 /// NR_026893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216333_x_at M25813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M25813.1 /DEF=Human unidentified gene complementary to P450c21 gene, partial cds. /FEA=mRNA /DB_XREF=gi:183069 /UG=Hs.283750 tenascin XA M25813 tenascin XA (pseudogene) /// tenascin XB TNXA /// TNXB 7146 /// 7148 NM_007116 /// NM_019105 /// NM_032470 /// NR_001284 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 216334_s_at U22030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U22030.1 /DEF=Human cytochrome P450 (CYP2A7PT) pseudogene mRNA, partial cds. /FEA=mRNA /GEN=CYP2A7PT /PROD=cytochrome P450 /DB_XREF=gi:1008467 /UG=Hs.283400 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7, pseudogene 1 U22030 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 CYP2A7P1 1550 216336_x_at AL031602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031602 /DEF=Human DNA sequence from clone RP5-1174N9 on chromosome 1p34.1-35.3. Contains the gene for a novel protein with IBR domain, a (pseudo?) gene for a novel protein similar to MT1E (metallothionein 1E (functional)), ESTs, STSs, GSSs and two putative Cp... /FEA=mRNA_1 /DB_XREF=gi:6729581 /UG=Hs.283842 Human DNA sequence from clone RP5-1174N9 on chromosome 1p34.1-35.3. Contains the gene for a novel protein with IBR domain, a (pseudo?) gene for a novel protein similar to MT1E (metallothionein 1E (functional)), ESTs, STSs, GSSs and two putative CpG island AL031602 metallothionein 1E MT1E 4493 NM_175617 /// XM_005255956 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 216337_at L23852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L23852.1 /DEF=Homo sapiens (clone Z146) retinal mRNA, 3 end and repeat region. /FEA=mRNA /DB_XREF=gi:393126 /UG=Hs.73838 Homo sapiens (clone Z146) retinal mRNA, 3 end and repeat region L23852 216338_s_at AK021433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021433.1 /DEF=Homo sapiens cDNA FLJ11371 fis, clone HEMBA1000356, highly similar to Homo sapiens mRNA; cDNA DKFZp566C243 (from clone DKFZp566C243). /FEA=mRNA /DB_XREF=gi:10432617 /UG=Hs.107747 DKFZP566C243 protein AK021433 Yip1 domain family, member 3 YIPF3 25844 NM_015388 /// XM_005248989 /// XM_005248990 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 216339_s_at AF086641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF086641 /DEF=Homo sapiens truncated tenascin XB (TNXB) gene, partial cds and TNXA gene recombination breakpoint region /FEA=mRNA /DB_XREF=gi:6448760 /UG=Hs.283750 tenascin XA AF086641 tenascin XA (pseudogene) /// tenascin XB TNXA /// TNXB 7146 /// 7148 NM_007116 /// NM_019105 /// NM_032470 /// NR_001284 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 216340_s_at U22044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U22044.1 /DEF=Human cytochrome P450 (CYP2A7PC) pseudogene mRNA, partial cds. /FEA=mRNA /GEN=CYP2A7PC /PROD=cytochrome P450 /DB_XREF=gi:1008468 /UG=Hs.283401 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7, pseudogene 2 U22044 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 CYP2A7P1 1550 216341_s_at Z81148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z81148.1 /DEF=H.sapiens mRNA for gonadotropin-releasing hormone receptor, splice variant. /FEA=mRNA /PROD=gonadotropin-releasing hormone receptor /DB_XREF=gi:1628389 /UG=Hs.73064 gonadotropin-releasing hormone receptor Z81148 gonadotropin-releasing hormone receptor GNRHR 2798 NM_000406 /// NM_001012763 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0097211 // cellular response to gonadotropin-releasing hormone // inferred from electronic annotation /// 0097211 // cellular response to gonadotropin-releasing hormone // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004968 // gonadotropin-releasing hormone receptor activity // inferred from electronic annotation /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 216342_x_at AL121916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121916 /DEF=Human DNA sequence from clone RP1-189G13 on chromosome 20. Contains an RPL7A (60S ribosomal protein L7A) (SURF3) pseudogene, part of an RPS4 (40S ribosomal protein S4) pseudogene, ESTs, STSs and GSSs /FEA=CDS_2 /DB_XREF=gi:7406639 /UG=Hs.283838 Human DNA sequence from clone RP1-189G13 on chromosome 20. Contains an RPL7A (60S ribosomal protein L7A) (SURF3) pseudogene, part of an RPS4 (40S ribosomal protein S4) pseudogene, ESTs, STSs and GSSs AL121916 ribosomal protein S4X pseudogene 2 /// RPS4XP2 /// RPS4XP2 216343_at AF152509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152509.1 /DEF=Homo sapiens PCDH-gamma-A3 gene, aberrantly spliced, mRNA sequence. /FEA=mRNA /DB_XREF=gi:5457066 /UG=Hs.283800 protocadherin gamma subfamily A, 3 AF152509 216344_at AL117405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117405.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1235 (from clone DKFZp434K1235); partial cds. /FEA=mRNA /GEN=DKFZp434K1235 /PROD=hypothetical protein /DB_XREF=gi:5911989 /UG=Hs.106487 KIAA0673 protein AL117405 nephronophthisis 4 NPHP4 261734 NM_001291593 /// NM_001291594 /// NM_015102 /// NR_111987 /// XM_006710563 /// XM_006710564 /// XM_006710565 /// XM_006710566 /// XM_006710567 /// XM_006710568 /// XM_006710569 /// XM_006710570 /// XR_244787 /// XR_426599 /// XR_426600 /// XR_426601 0007165 // signal transduction // non-traceable author statement /// 0007632 // visual behavior // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred by curator /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 216345_at AB020720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020720.1 /DEF=Homo sapiens mRNA for KIAA0913 protein, partial cds. /FEA=mRNA /GEN=KIAA0913 /PROD=KIAA0913 protein /DB_XREF=gi:4240314 /UG=Hs.65135 KIAA0913 protein AB020720 zinc finger, SWIM-type containing 8 ZSWIM8 23053 NM_001242487 /// NM_001242488 /// NM_015037 /// XM_005269648 /// XM_005269649 /// XM_005269651 /// XM_005269652 /// XM_005269653 /// XM_005269655 /// XM_006717725 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216346_at AC004832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004832 /DEF=Homo sapiens PAC clone RP4-539M6 from 22 /FEA=CDS_1 /DB_XREF=gi:6624129 /UG=Hs.283777 Homo sapiens PAC clone RP4-539M6 from 22 AC004832 SEC14-like 3 (S. cerevisiae) SEC14L3 266629 NM_001257378 /// NM_001257379 /// NM_001257382 /// NM_174975 /// XM_005261527 0006810 // transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 216347_s_at AK023188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023188.1 /DEF=Homo sapiens cDNA FLJ13126 fis, clone NT2RP3002909, weakly similar to P53-BINDING PROTEIN 2. /FEA=mRNA /DB_XREF=gi:10435002 /UG=Hs.6162 KIAA0771 protein AK023188 protein phosphatase 1, regulatory subunit 13B PPP1R13B 23368 NM_015316 /// XM_005267484 /// XM_005267485 /// XM_005267487 /// XR_245675 /// XR_245676 0006915 // apoptotic process // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation 216348_at AL049693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049693 /DEF=Human DNA sequence from clone RP4-753D5 on chromosome 6p12.1-12.3. Contains the 3 end of the TFAP2B gene for transcription factor AP-2 beta (activating enhancer-binding protein 2 beta), the gene for a novel protein similar to RPS17 (40S ribosomal... /FEA=mRNA_1 /DB_XREF=gi:7378744 /UG=Hs.283833 Human DNA sequence from clone RP4-753D5 on chromosome 6p12.1-12.3. Contains the 3 end of the TFAP2B gene for transcription factor AP-2 beta (activating enhancer-binding protein 2 beta), the gene for a novel protein similar to RPS17 (40S ribosomal protein AL049693 ribosomal protein S17 pseudogene 5 /// RPS17P5 /// RPS17P5 216349_at AL136527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136527 /DEF=Human DNA sequence from clone RP11-215B13 on chromosome 13 Contains the AKAP11 (A kinase (PRKA) anchor protein 11) gene, part of a gene similar to FH (fumarate hydratase), ESTs, STSs, GSSs and a CpG Island /FEA=mRNA_1 /DB_XREF=gi:7406538 /UG=Hs.283831 Human DNA sequence from clone RP11-215B13 on chromosome 13 Contains the AKAP11 (A kinase (PRKA) anchor protein 11) gene, part of a gene similar to FH (fumarate hydratase), ESTs, STSs, GSSs and a CpG Island AL136527 diacylglycerol kinase, eta DGKH 160851 NM_001204504 /// NM_001204505 /// NM_001204506 /// NM_001297429 /// NM_152910 /// NM_178009 /// NR_123714 /// NR_123715 /// XM_005266271 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216350_s_at X52332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52332.1 /DEF=Homo sapiens mRNA for zinc finger protein 10. /FEA=mRNA /GEN=Kox1 /PROD=zinc finger protein 10 /DB_XREF=gi:34141 /UG=Hs.104115 DKFZP434G1621 protein X52332 zinc finger protein 10 ZNF10 7556 NM_015394 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216351_x_at AF248483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF248483.1 /DEF=Homo sapiens deleted in azoospermia 4 (DAZ4) mRNA, partial cds. /FEA=mRNA /GEN=DAZ4 /PROD=deleted in azoospermia 4 /DB_XREF=gi:9651960 /UG=Hs.283814 deleted in azoospermia 4 AF248483 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 216352_x_at AF152509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152509.1 /DEF=Homo sapiens PCDH-gamma-A3 gene, aberrantly spliced, mRNA sequence. /FEA=mRNA /DB_XREF=gi:5457066 /UG=Hs.283800 protocadherin gamma subfamily A, 3 AF152509 protocadherin gamma subfamily A, 3 PCDHGA3 56112 NM_018916 /// NM_032011 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216353_s_at AL121582 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121582 /DEF=Human DNA sequence from clone RP11-280O9 on chromosome 20. Contains an RNF11 (ring finger protein 11) (SID1669) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:8218070 /UG=Hs.283868 Human DNA sequence from clone RP11-280O9 on chromosome 20. Contains an RNF11 (ring finger protein 11) (SID1669) pseudogene, ESTs, STSs and GSSs AL121582 RNF11B 216354_at AL031669 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031669 /DEF=Human DNA sequence from clone RP4-661I20 on chromosome 20q11.23-12 Contains a gene for a protein similar to RPL12 (ribosomal protein L12), part of a novel Helicase C-terminal domain and SNF2 N-terminal domains containing protein, ESTs, STSs, GSSs ... /FEA=mRNA /DB_XREF=gi:8218059 /UG=Hs.283847 Human DNA sequence from clone RP4-661I20 on chromosome 20q11.23-12 Contains a gene for a protein similar to RPL12 (ribosomal protein L12), part of a novel Helicase C-terminal domain and SNF2 N-terminal domains containing protein, ESTs, STSs, GSSs and CpG AL031669 216355_at AF152527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF152527.1 /DEF=Homo sapiens PCDH-psi1 pseudogene, mRNA sequence. /FEA=mRNA /DB_XREF=gi:5457101 /UG=Hs.284307 protocadherin beta 17 pseudogene AF152527 216356_x_at AB018277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB018277.1 /DEF=Homo sapiens mRNA for KIAA0734 protein, partial cds. /FEA=mRNA /GEN=KIAA0734 /PROD=KIAA0734 protein /DB_XREF=gi:3882188 /UG=Hs.101516 BAI1-associated protein 3 AB018277 BAI1-associated protein 3 BAIAP3 8938 NM_001199096 /// NM_001199097 /// NM_001199098 /// NM_001199099 /// NM_001286464 /// NM_003933 0007186 // G-protein coupled receptor signaling pathway // inferred from physical interaction /// 0007269 // neurotransmitter secretion // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement 216357_at AL050148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050148.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586G1520 (from clone DKFZp586G1520). /FEA=mRNA /DB_XREF=gi:4884359 /UG=Hs.31834 Homo sapiens clone 25129 mRNA sequence AL050148 sorting nexin 1 SNX1 6642 NM_001242933 /// NM_003099 /// NM_148955 /// NM_152826 /// XM_005254610 /// XM_005254611 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 216358_at AL137010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137010 /DEF=Human DNA sequence from clone RP3-526L9 on chromosome 6. Contains a SMARCE1 (SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1) pseudogene, ESTs and GSSs /FEA=CDS /DB_XREF=gi:8649454 /UG=Hs.283863 Human DNA sequence from clone RP3-526L9 on chromosome 6. Contains a SMARCE1 (SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1) pseudogene, ESTs and GSSs AL137010 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene 2 /// SMARCE1P2 /// SMARCE1P2 216359_at L13283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13283.1 /DEF=Homo sapiens (clone MG2-5-12) mucin (MG2) mRNA, complete polyA site. /FEA=mRNA /DB_XREF=gi:292518 /UG=Hs.103944 Homo sapiens (clone MG2-5-12) mucin (MG2) mRNA, complete polyA site L13283 mucin 7, secreted MUC7 4589 NM_001145006 /// NM_001145007 /// NM_152291 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 216360_x_at AK000238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000238.1 /DEF=Homo sapiens cDNA FLJ20231 fis, clone COLF5511, highly similar to AB014590 Homo sapiens mRNA for KIAA0690 protein. /FEA=mRNA /DB_XREF=gi:7020188 /UG=Hs.60103 KIAA0690 protein AK000238 ribosomal RNA processing 12 homolog (S. cerevisiae) RRP12 23223 NM_001145114 /// NM_001284337 /// NM_015179 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216361_s_at AJ251844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ251844.1 /DEF=Homo sapiens partial mRNA for MOZCBP chimeric transcript type II. /FEA=mRNA /GEN=MOZCBP /PROD=MOZCBP /DB_XREF=gi:9368433 /UG=Hs.283860 Homo sapiens partial mRNA for MOZCBP chimeric transcript type II AJ251844 K(lysine) acetyltransferase 6A KAT6A 7994 NM_001099412 /// NM_001099413 /// NM_006766 /// XM_005273649 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216362_at AJ251844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ251844.1 /DEF=Homo sapiens partial mRNA for MOZCBP chimeric transcript type II. /FEA=mRNA /GEN=MOZCBP /PROD=MOZCBP /DB_XREF=gi:9368433 /UG=Hs.283860 Homo sapiens partial mRNA for MOZCBP chimeric transcript type II AJ251844 216363_at S73614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S73614.1 /DEF=Homo sapiens transgenic-JHD mouse 2357 immunoglobulin heavy chain variable region (IgG VH251) mRNA, partial cds. /FEA=mRNA /GEN=IgG VH251 /DB_XREF=gi:688334 /UG=Hs.283878 Homo sapiens transgenic-JHD mouse 2357 immunoglobulin heavy chain variable region (IgG VH251) mRNA, partial cds S73614 216364_s_at AJ001550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001550.1 /DEF=Homo sapiens mRNA for FMR2 protein. /FEA=CDS /GEN=fmr2 /PROD=FMR2 protein /DB_XREF=gi:2832397 /UG=Hs.54472 fragile X mental retardation 2 AJ001550 AF4/FMR2 family, member 2 AFF2 2334 NM_001169122 /// NM_001169123 /// NM_001169124 /// NM_001169125 /// NM_001170628 /// NM_002025 0006397 // mRNA processing // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0002151 // G-quadruplex RNA binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation 216365_x_at AF047245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF047245.1 /DEF=Homo sapiens clone bsmneg3-t7 immunoglobulin lambda light chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda light chain /DB_XREF=gi:4566041 /UG=Hs.283876 Homo sapiens clone bsmneg3-t7 immunoglobulin lambda light chain VJ region, (IGL) mRNA, partial cds AF047245 cytoskeleton associated protein 2 /// immunoglobulin lambda joining 3 /// /// immunoglobulin lambda variable 3-19 CKAP2 /// IGLJ3 /// IGLV3-19 /// IGLV3-19 26586 /// 28831 NM_001098525 /// NM_001286686 /// NM_001286687 /// NM_018204 /// XM_005266343 /// XM_005266344 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 216366_x_at AF047245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF047245.1 /DEF=Homo sapiens clone bsmneg3-t7 immunoglobulin lambda light chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda light chain /DB_XREF=gi:4566041 /UG=Hs.283876 Homo sapiens clone bsmneg3-t7 immunoglobulin lambda light chain VJ region, (IGL) mRNA, partial cds AF047245 216367_at U02520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02520.1 /DEF=Human collagen type IV alpha 3 mRNA, partial cds. /FEA=mRNA /PROD=collagen type IV alpha 3 /DB_XREF=gi:408895 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) U02520 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 216368_s_at U02520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02520.1 /DEF=Human collagen type IV alpha 3 mRNA, partial cds. /FEA=mRNA /PROD=collagen type IV alpha 3 /DB_XREF=gi:408895 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) U02520 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 216369_at AF203728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF203728.1 /DEF=Homo sapiens bone morphogenetic protein BMPY (BMPY) mRNA, partial cds. /FEA=mRNA /GEN=BMPY /PROD=bone morphogenetic protein BMPY /DB_XREF=gi:6525028 /UG=Hs.283898 Homo sapiens bone morphogenetic protein BMPY (BMPY) mRNA, partial cds AF203728 0005576 // extracellular region // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 216370_s_at Z49258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z49258 /DEF=Human DNA sequence from cosmid 14B7 in Xq28 containing transketolase pseudogene /FEA=CDS /DB_XREF=gi:807880 /UG=Hs.102866 transketolase-like 1 Z49258 transketolase-like 1 TKTL1 8277 NM_001145933 /// NM_001145934 /// NM_012253 0006007 // glucose catabolic process // traceable author statement /// 0006772 // thiamine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004802 // transketolase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216371_at AF103295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103295.1 /DEF=Homo sapiens clone N97 immunoglobulin heavy chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin heavy chain variable region /DB_XREF=gi:4838126 /UG=Hs.283882 Homo sapiens clone N97 immunoglobulin heavy chain variable region mRNA, partial cds AF103295 216372_at AF103295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103295.1 /DEF=Homo sapiens clone N97 immunoglobulin heavy chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin heavy chain variable region /DB_XREF=gi:4838126 /UG=Hs.283882 Homo sapiens clone N97 immunoglobulin heavy chain variable region mRNA, partial cds AF103295 216373_at AF189251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF189251.1 /DEF=Homo sapiens cytomegalovirus partial fusion receptor mRNA, partial cds. /FEA=mRNA /PROD=cytomegalovirus partial fusion receptor /DB_XREF=gi:6760349 /UG=Hs.283927 Homo sapiens cytomegalovirus partial fusion receptor mRNA, partial cds AF189251 transmembrane anterior posterior transformation 1 TAPT1 202018 NM_153365 /// XM_005248139 /// XM_005248140 /// XM_005248141 /// XM_005248142 /// XR_241676 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0016520 // growth hormone-releasing hormone receptor activity // traceable author statement 216374_at AC006986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006986 /DEF=Homo sapiens BAC clone RP11-155J5 from Y /FEA=CDS /DB_XREF=gi:4753246 /UG=Hs.283908 Homo sapiens BAC clone RP11-155J5 from Y AC006986 testis specific protein, Y-linked 13, pseudogene /// TSPY13P /// TSPY13P 216375_s_at X76184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X76184.1 /DEF=H.sapiens mRNA for ets-related protein. /FEA=mRNA /GEN=erm /PROD=ets-related protein /DB_XREF=gi:479166 /UG=Hs.43697 ets variant gene 5 (ets-related molecule) X76184 ets variant 5 ETV5 2119 NM_004454 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 216376_x_at AC006371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006371 /DEF=Homo sapiens BAC clone RP11-304C24 from Y /FEA=CDS_1 /DB_XREF=gi:5757526 /UG=Hs.283905 Homo sapiens BAC clone RP11-304C24 from Y AC006371 Kallmann syndrome sequence pseudogene /// KALP /// KALP 216377_x_at X07247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07247 /DEF=Human placental alkaline phosphatase-like gene 5 region /FEA=CDS /DB_XREF=gi:35509 /UG=Hs.284255 alkaline phosphatase, placental (Regan isozyme) X07247 alkaline phosphatase, placental-like 2 ALPPL2 251 NM_031313 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004035 // alkaline phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216378_at AF168811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF168811 /DEF=Homo sapiens clone case06H1 immunoglobulin heavy chain variable region gene, partial cds /FEA=CDS /DB_XREF=gi:5833844 /UG=Hs.283924 Homo sapiens clone case06H1 immunoglobulin heavy chain variable region gene, partial cds AF168811 216379_x_at AK000168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000168.1 /DEF=Homo sapiens cDNA FLJ20161 fis, clone COL09252, highly similar to L33930 Homo sapiens CD24 signal transducer mRNA. /FEA=mRNA /DB_XREF=gi:7020079 /UG=Hs.332045 Homo sapiens cDNA FLJ20161 fis, clone COL09252, highly similar to L33930 Homo sapiens CD24 signal transducer mRNA AK000168 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 216380_x_at AC005011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005011 /DEF=Homo sapiens BAC clone GS1-111G14 from 7q11 /FEA=CDS /DB_XREF=gi:4753254 /UG=Hs.283909 Homo sapiens BAC clone GS1-111G14 from 7q11 AC005011 GS1-111G14.1 216381_x_at AL035413 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035413 /DEF=Human DNA sequence from clone RP4-657E11 on chromosome 1p35.1-36.23 Contains 3 part of the CAPZB (capping protein (actin filament) muscle Z-line, beta) gene, genes for aldo-keto reductase family 7 (aflatoxin aldehyde reductase) members A2 (AKR7A2... /FEA=mRNA_1 /DB_XREF=gi:6010110 /UG=Hs.284236 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) AL035413 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) AKR7A3 22977 NM_012067 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0046222 // aflatoxin metabolic process // inferred from electronic annotation /// 0046223 // aflatoxin catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from electronic annotation /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 216382_s_at U80756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80756.1 /DEF=Homo sapiens CAGL114 mRNA, partial cds. /FEA=mRNA /GEN=CAGL114 /DB_XREF=gi:2565081 /UG=Hs.326533 trinucleotide repeat containing 21 U80756 216383_at U52111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U52111 /DEF=Homo sapiens X28 region near ALD locus containing dual specificity phosphatase 9 (DUSP9), ribosomal protein L18a (RPL18a), Ca2+Calmodulin-dependent protein kinase I (CAMKI), creatine transporter (CRTR), CDM protein (CDM), adrenoleukodystrophy pro... /FEA=mRNA_2 /DB_XREF=gi:8331754 /UG=Hs.283952 Homo sapiens X28 region near ALD locus containing dual specificity phosphatase 9 (DUSP9), ribosomal protein L18a (RPL18a), Ca2+Calmodulin-dependent protein kinase I (CAMKI), creatine transporter (CRTR), CDM protein (CDM), adrenoleukodystrophy protein (AL U52111 ribosomal protein L18a pseudogene 16 /// RPL18AP16 /// RPL18AP16 216384_x_at AF257099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF257099 /DEF=Homo sapiens prothymosin alpha (PTMA) gene, complete cds /FEA=CDS /DB_XREF=gi:8037944 /UG=Hs.283947 Homo sapiens prothymosin alpha (PTMA) gene, complete cds AF257099 prothymosin alpha-like /// prothymosin alpha-like /// microRNA 1244-1 /// microRNA 1244-2 /// microRNA 1244-3 /// prothymosin, alpha LOC100506248 /// LOC728026 /// MIR1244-1 /// MIR1244-2 /// MIR1244-3 /// PTMA 5757 /// 728026 /// 100302285 /// 100422872 /// 100422885 /// 100506248 NM_001099285 /// NM_002823 /// NR_036052 /// NR_036262 /// NR_036263 /// XM_001126659 /// XM_003960458 /// XM_005275719 /// XM_005276418 0006351 // transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 216385_at AF229166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229166.1 /DEF=Homo sapiens docking protein 1-like protein mRNA, partial cds. /FEA=mRNA /PROD=docking protein 1-like protein /DB_XREF=gi:7650361 /UG=Hs.283936 Homo sapiens docking protein 1-like protein mRNA, partial cds AF229166 dedicator of cytokinesis 1 pseudogene LOC220077 220077 0005158 // insulin receptor binding // inferred from electronic annotation 216386_at AF229166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229166.1 /DEF=Homo sapiens docking protein 1-like protein mRNA, partial cds. /FEA=mRNA /PROD=docking protein 1-like protein /DB_XREF=gi:7650361 /UG=Hs.283936 Homo sapiens docking protein 1-like protein mRNA, partial cds AF229166 dedicator of cytokinesis 1 pseudogene LOC220077 220077 0005158 // insulin receptor binding // inferred from electronic annotation 216387_x_at AL353580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353580 /DEF=Human DNA sequence from clone RP11-248N6 on chromosome 13 Contains ESTs, STSs and GSSs. Contains two olfactory receptor pseudogenes, an NPM1 (nucleophosmin, nucleolar phosphoprotein B23, numatrin) pseudogene and a BCR (breakpoint cluster region) p... /FEA=CDS_2 /DB_XREF=gi:9944152 /UG=Hs.326589 Human DNA sequence from clone RP11-248N6 on chromosome 13 Contains ESTs, STSs and GSSs. Contains two olfactory receptor pseudogenes, an NPM1 (nucleophosmin, nucleolar phosphoprotein B23, numatrin) pseudogene and a BCR (breakpoint cluster region) pseudogen AL353580 nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 22 /// NPM1P22 /// NPM1P22 216388_s_at U33448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U33448 /DEF=Human putative G-protein-coupled receptor (GPR16) gene, complete cds /FEA=CDS /DB_XREF=gi:1613770 /UG=Hs.28408 leukotriene b4 receptor (chemokine receptor-like 1) U33448 leukotriene B4 receptor LTB4R 1241 NM_001143919 /// NM_181657 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // traceable author statement /// 0001632 // leukotriene B4 receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // traceable author statement 216389_s_at AF283773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF283773.2 /DEF=Homo Sapiens clone TCBAP0888 mRNA sequence. /FEA=mRNA /DB_XREF=gi:10281743 /UG=Hs.283976 hypthetical protein PRO2389 AF283773 DDB1 and CUL4 associated factor 11 DCAF11 80344 NM_001163484 /// NM_025230 /// NM_181357 /// NR_028099 /// NR_028100 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 216390_at X06537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06537.1 /DEF=Human mRNA for lecithin:cholesterol acyltransferase (LCAT); EC 2.3.1.43. /FEA=mRNA /GEN=LCAT /PROD=lectin cholesterol acyltransferase /DB_XREF=gi:34284 /UG=Hs.325507 lecithin-cholesterol acyltransferase X06537 lecithin-cholesterol acyltransferase LCAT 3931 NM_000229 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0030301 // cholesterol transport // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from direct assay /// 0034435 // cholesterol esterification // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0090107 // regulation of high-density lipoprotein particle assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004607 // phosphatidylcholine-sterol O-acyltransferase activity // inferred from direct assay /// 0004607 // phosphatidylcholine-sterol O-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction 216391_s_at AF126749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF126749.1 /DEF=Homo sapiens SCA8 mRNA, repeat region. /FEA=mRNA /DB_XREF=gi:4589125 /UG=Hs.286079 spinocerebellar ataxia 8 AF126749 kelch-like family member 1 KLHL1 57626 NM_001286725 /// NM_020866 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216392_s_at AK021846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021846.1 /DEF=Homo sapiens cDNA FLJ11784 fis, clone HEMBA1006031, highly similar to Homo sapiens mRNA for putative phospholipase. /FEA=mRNA /DB_XREF=gi:10433116 /UG=Hs.300208 Sec23-interacting protein p125 AK021846 SEC23 interacting protein SEC23IP 11196 NM_007190 /// NR_037771 /// XM_005269469 /// XM_005269470 /// XR_246061 0006886 // intracellular protein transport // traceable author statement /// 0007030 // Golgi organization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216393_at AL049938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049938.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P1916 (from clone DKFZp564P1916); partial cds. /FEA=mRNA /GEN=DKFZp564P1916 /PROD=hypothetical protein /DB_XREF=gi:4884179 /UG=Hs.285391 DKFZP564P1916 protein AL049938 chromosome 10 open reading frame 12 C10orf12 26148 NM_015652 216394_x_at AF043586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043586.1 /DEF=Homo sapiens clone CPRF1-T2 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865483 /UG=Hs.287816 Homo sapiens clone CPRF1-T2 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043586 216395_at AL137434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137434.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G1824 (from clone DKFZp761G1824). /FEA=mRNA /DB_XREF=gi:6807993 /UG=Hs.287418 hypothetical protein FLJ11467 AL137434 F-box and leucine-rich repeat protein 18 FBXL18 80028 NM_024963 /// XM_005249853 /// XM_005249854 216396_s_at AF131850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131850.1 /DEF=Homo sapiens clone 24988 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406694 /UG=Hs.286027 etoposide-induced mRNA AF131850 etoposide induced 2.4 EI24 9538 NM_001007277 /// NM_001290135 /// NM_004879 /// NR_110769 /// NR_110770 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 216397_s_at AK024840 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024840.1 /DEF=Homo sapiens cDNA: FLJ21187 fis, clone CAS11730. /FEA=mRNA /DB_XREF=gi:10437246 /UG=Hs.30736 KIAA0124 protein AK024840 block of proliferation 1 /// microRNA 7112 BOP1 /// MIR7112 23246 /// 102465906 NM_015201 /// NR_107057 0000463 // maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0000466 // maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0042254 // ribosome biogenesis // inferred by curator /// 0042254 // ribosome biogenesis // non-traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030687 // preribosome, large subunit precursor // inferred from electronic annotation /// 0070545 // PeBoW complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216398_at U05255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U05255.1 /DEF=Human glycophorin HeP2 mRNA, partial cds. /FEA=mRNA /PROD=glycophorin HeP2 /DB_XREF=gi:454085 /UG=Hs.307185 Human glycophorin HeP2 mRNA, partial cds U05255 glycophorin B (MNS blood group) GYPB 2994 NM_002100 /// XM_005262968 /// XM_005262969 /// XM_005262970 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 216399_s_at AK025663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025663.1 /DEF=Homo sapiens cDNA: FLJ22010 fis, clone HEP07134. /FEA=mRNA /DB_XREF=gi:10438253 /UG=Hs.285848 KIAA1454 protein AK025663 S-phase cyclin A-associated protein in the ER SCAPER 49855 NM_001145923 /// NM_020843 /// XM_005254417 /// XM_005254419 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216400_at M18917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M18917 /DEF=Human glucocerebrosidase gene 10-2, 5 end /FEA=CDS_1 /DB_XREF=gi:183025 /UG=Hs.287396 Human glucocerebrosidase gene 10-2, 5 end M18917 glucosidase, beta, acid pseudogene 1 /// glucosylceramidase-like GBAP1 /// LOC100510710 2630 /// 100510710 NR_002188 /// XR_431075 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006680 // glucosylceramide catabolic process // inferred from mutant phenotype /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046512 // sphingosine biosynthetic process // inferred from mutant phenotype /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0097066 // response to thyroid hormone // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004348 // glucosylceramidase activity // inferred from electronic annotation /// 0004348 // glucosylceramidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 216401_x_at AJ408433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ408433 /DEF=Homo sapiens partial IGKV gene for immunoglobulin kappa chain variable region, clone 38 /FEA=CDS /DB_XREF=gi:12655549 /UG=Hs.307136 Homo sapiens partial IGKV gene for immunoglobulin kappa chain variable region, clone 38 AJ408433 immunoglobulin kappa variable 1-37 (non-functional) /// /// immunoglobulin kappa variable 1D-37 (non-functional) /// IGKV1-37 /// IGKV1-37 /// IGKV1D-37 /// IGKV1D-37 0005515 // protein binding // inferred from electronic annotation 216402_at AC004832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004832 /DEF=Homo sapiens PAC clone RP4-539M6 from 22 /FEA=CDS_2 /DB_XREF=gi:6624129 /UG=Hs.287352 Homo sapiens PAC clone RP4-539M6 from 22 AC004832 SEC14-like 4 (S. cerevisiae) SEC14L4 284904 NM_001161368 /// NM_174977 /// XM_005261583 /// XM_006724231 /// XM_006724232 /// XM_006724233 /// XM_006724234 /// XM_006724235 0006810 // transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 216403_at AL163533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL163533 /DEF=Human DNA sequence from clone RP11-114G1 on chromosome 13q31.3-33.1 Contains a pseudogene similar to transcription factor SP1, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9800736 /UG=Hs.307131 Human DNA sequence from clone RP11-114G1 on chromosome 13q31.3-33.1 Contains a pseudogene similar to transcription factor SP1, ESTs, STSs and GSSs AL163533 Sp3 transcription factor pseudogene SP3P 160824 216404_at AF126749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF126749.1 /DEF=Homo sapiens SCA8 mRNA, repeat region. /FEA=mRNA /DB_XREF=gi:4589125 /UG=Hs.286079 spinocerebellar ataxia 8 AF126749 ATXN8 opposite strand (non-protein coding) ATXN8OS 6315 NR_002717 216405_at M14087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M14087.1 /DEF=Human HL14 gene encoding beta-galactoside-binding lectin, 3 end, clone 2. /FEA=mRNA /DB_XREF=gi:187113 /UG=Hs.287389 Human HL14 gene encoding beta-galactoside-binding lectin, 3 end, clone 2 M14087 0002317 // plasma cell differentiation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from direct assay /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034120 // positive regulation of erythrocyte aggregation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // non-traceable author statement /// 0016936 // galactoside binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030395 // lactose binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation 216406_at AL390237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390237 /DEF=Human DNA sequence from clone RP11-278J20 on chromosome 6. Contains ESTs, STSs and GSSs. Contains an RBBP4 (retinoblastoma-binding protein 4) pseudogene and a KIAA0797 pseudogene /FEA=CDS_2 /DB_XREF=gi:10120117 /UG=Hs.307105 Human DNA sequence from clone RP11-278J20 on chromosome 6. Contains ESTs, STSs and GSSs. Contains an RBBP4 (retinoblastoma-binding protein 4) pseudogene and a KIAA0797 pseudogene AL390237 RP11-278J20.2 216407_at U25801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U25801.1 /DEF=Human Tax1 binding protein mRNA, partial cds. /FEA=mRNA /PROD=Tax1 binding protein /DB_XREF=gi:1122440 /UG=Hs.287365 Tax1 (human T-cell leukemia virus type I) binding protein 1 U25801 Vac14 homolog (S. cerevisiae) VAC14 55697 NM_018052 /// XM_005256038 /// XM_005256039 /// XM_005256040 /// XM_005256041 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070772 // PAS complex // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 216408_at AJ302584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ302584 /DEF=Homo sapiens 6M1-10*01 gene for olfactory receptor, cell line BM28.7 /FEA=CDS /DB_XREF=gi:12054392 /UG=Hs.307111 Homo sapiens 6M1-10*01 gene for olfactory receptor, cell line BM28.7 AJ302584 olfactory receptor, family 2, subfamily B, member 2 OR2B2 81697 NM_033057 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 216409_at AL390168 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390168.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547D104 (from clone DKFZp547D104). /FEA=mRNA /GEN=DKFZp547D104 /PROD=hypothetical protein /DB_XREF=gi:9368863 /UG=Hs.287371 hypothetical protein DKFZp547D104 AL390168 acyl-CoA synthetase long-chain family member 6 ACSL6 23305 NM_001009185 /// NM_001205247 /// NM_001205248 /// NM_001205250 /// NM_001205251 /// NM_015256 /// XM_006714579 /// XM_006714580 /// XM_006714581 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // non-traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010747 // positive regulation of plasma membrane long-chain fatty acid transport // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 216410_at AL137181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137181 /DEF=Human DNA sequence from clone RP1-23O21 on chromosome 6. Contains an acidic calponin 3 (CNN3) pseudogene, STSs and GSSs /FEA=CDS /DB_XREF=gi:8894200 /UG=Hs.287763 Human DNA sequence from clone RP1-23O21 on chromosome 6. Contains an acidic calponin 3 (CNN3) pseudogene, STSs and GSSs AL137181 calponin 3, acidic pseudogene 1 /// CNN3P1 /// CNN3P1 216411_s_at AK023699 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023699.1 /DEF=Homo sapiens cDNA FLJ13637 fis, clone PLACE1011165. /FEA=mRNA /DB_XREF=gi:10435704 /UG=Hs.287584 Homo sapiens cDNA FLJ13637 fis, clone PLACE1011165 AK023699 galactokinase 2 GALK2 2585 NM_001001556 /// NM_001289030 /// NM_001289031 /// NM_002044 /// XM_005254279 /// XM_005254280 /// XM_005254284 /// XM_006720461 /// XM_006720462 /// XM_006720463 /// XM_006720464 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004335 // galactokinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0033858 // N-acetylgalactosamine kinase activity // inferred from electronic annotation 216412_x_at AF043584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043584.1 /DEF=Homo sapiens clone ASMneg1-b1 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865479 /UG=Hs.287815 Homo sapiens clone ASMneg1-b1 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043584 cytoskeleton associated protein 2 /// immunoglobulin lambda constant 1 (Mcg marker) /// /// immunoglobulin lambda variable 1-40 /// /// immunoglobulin lambda variable 1-50 (non-functional) CKAP2 /// IGLC1 /// IGLV1-40 /// IGLV1-40 /// IGLV1-50 /// IGLV1-50 3537 /// 26586 NM_001098525 /// NM_001286686 /// NM_001286687 /// NM_018204 /// XM_005266343 /// XM_005266344 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216413_at AL139112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139112 /DEF=Human DNA sequence from clone GS1-103B18 on chromosome Xq27.1-27.3 Contains ESTs, STSs and GSSs. Contains a novel cytochrome c-1 (CYC1) pseudogene /FEA=CDS /DB_XREF=gi:10045312 /UG=Hs.307101 Human DNA sequence from clone GS1-103B18 on chromosome Xq27.1-27.3 Contains ESTs, STSs and GSSs. Contains a novel cytochrome c-1 (CYC1) pseudogene AL139112 cytochrome c, somatic pseudogene 44 /// CYCSP44 /// GS1-103B18.1 216414_at AL136094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136094 /DEF=Human DNA sequence from clone RP3-527B10 on chromosome 6q25.1-25.3 Contains a pseudogene similar to HMG (high mobility group) protein, STSs and GSSs /FEA=CDS /DB_XREF=gi:9187149 /UG=Hs.287762 Human DNA sequence from clone RP3-527B10 on chromosome 6q25.1-25.3 Contains a pseudogene similar to HMG (high mobility group) protein, STSs and GSSs AL136094 high mobility group box 3 pseudogene 19 /// HMGB3P19 /// HMGB3P19 216415_at AK026793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026793.1 /DEF=Homo sapiens cDNA: FLJ23140 fis, clone LNG09065. /FEA=mRNA /DB_XREF=gi:10439729 /UG=Hs.287728 Homo sapiens cDNA: FLJ23140 fis, clone LNG09065 AK026793 dynein, axonemal, heavy chain 3 DNAH3 55567 NM_017539 /// XM_006721062 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 216416_at AK027254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027254.1 /DEF=Homo sapiens cDNA: FLJ23601 fis, clone LNG15501. /FEA=mRNA /DB_XREF=gi:10440343 /UG=Hs.306918 Homo sapiens cDNA: FLJ23601 fis, clone LNG15501 AK027254 216417_x_at X16172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16172 /DEF=Human HOX-2.5 gene for homeodomain protein, partial /FEA=CDS /DB_XREF=gi:32374 /UG=Hs.287809 Human HOX-2.5 gene for homeodomain protein, partial X16172 homeobox B9 HOXB9 3219 NM_024017 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216418_at AL133173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133173 /DEF=Human DNA sequence from clone RP11-453N3 on chromosome 10 Contains the 3 end of a gene similar to ABCD1 (ATP-binding cassette, sub-family D (ALD), member 1), an EST, STSs, GSSs and CpG islands /FEA=mRNA /DB_XREF=gi:8217417 /UG=Hs.287782 Human DNA sequence from clone RP11-453N3 on chromosome 10 Contains the 3 end of a gene similar to ABCD1 (ATP-binding cassette, sub-family D (ALD), member 1), an EST, STSs, GSSs and CpG islands AL133173 ATP-binding cassette, sub-family D (ALD), member 1, pseudogene 2 /// ABCD1P2 /// ABCD1P2 216419_at AK026910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026910.1 /DEF=Homo sapiens cDNA: FLJ23257 fis, clone COL05579. /FEA=mRNA /DB_XREF=gi:10439880 /UG=Hs.306896 Homo sapiens cDNA: FLJ23257 fis, clone COL05579 AK026910 ciliary rootlet coiled-coil, rootletin CROCC 9696 NM_014675 /// XM_006711056 /// XM_006711057 /// XM_006711058 /// XM_006711059 /// XM_006711060 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from sequence or structural similarity 216420_at AL359954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359954 /DEF=Human DNA sequence from clone RP11-318P23 on chromosome 20 Contains a TAR DNA-binding protein pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:10045477 /UG=Hs.287778 Human DNA sequence from clone RP11-318P23 on chromosome 20 Contains a TAR DNA-binding protein pseudogene, ESTs, STSs and GSSs AL359954 TAR DNA binding protein pseudogene 1 /// TARDBPP1 /// TARDBPP1 216421_at AL121886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121886 /DEF=Human DNA sequence from clone RP5-1028D15 on chromosome 20. Contains the 3 end of the gene for CGI-53 protein (ortholog of rodent NGD5), a (possibly pseudo) gene for a protein similar to RPL27A (ribosomal protein L27a), the MYBL2 gene for v-myb a... /FEA=mRNA_1 /DB_XREF=gi:8247022 /UG=Hs.287772 Human DNA sequence from clone RP5-1028D15 on chromosome 20. Contains the 3 end of the gene for CGI-53 protein (ortholog of rodent NGD5), a (possibly pseudo) gene for a protein similar to RPL27A (ribosomal protein L27a), the MYBL2 gene for v-myb avian mye AL121886 ribosomal protein L27a pseudogene /// RPL27AP /// RPL27AP 216422_at AL136460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136460 /DEF=Human DNA sequence from clone RP11-102J14 on chromosome 20. Contains a novel gene and a novel pseudogene similar to the mouse PLFAP gene for proliferation associated protein 1. Contains ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9650519 /UG=Hs.287770 Human DNA sequence from clone RP11-102J14 on chromosome 20. Contains a novel gene and a novel pseudogene similar to the mouse PLFAP gene for proliferation associated protein 1. Contains ESTs, STSs and GSSs AL136460 proliferation-associated 2G4 pseudogene 2 /// PA2G4P2 /// PA2G4P2 216423_at AK026694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026694.1 /DEF=Homo sapiens cDNA: FLJ23041 fis, clone LNG02288. /FEA=mRNA /DB_XREF=gi:10439604 /UG=Hs.306865 Homo sapiens cDNA: FLJ23041 fis, clone LNG02288 AK026694 216424_at S79267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S79267.1 /DEF=CD4 receptor {exons 1 and 2} human, T-lymphocyte, mRNA, 3429 nt. /FEA=mRNA /GEN=CD4 receptor /PROD=CD4 receptor /DB_XREF=gi:1086922 /UG=Hs.287807 CD4 receptor {exons 1 and 2} human, T-lymphocyte, mRNA, 3429 nt S79267 CD4 molecule CD4 920 NM_000616 /// NM_001195014 /// NM_001195015 /// NM_001195016 /// NM_001195017 /// NR_036545 0001816 // cytokine production // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006948 // induction by virus of host cell-cell fusion // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0030217 // T cell differentiation // inferred from direct assay /// 0030260 // entry into host cell // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032507 // maintenance of protein location in cell // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0045058 // T cell selection // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045234 // protein palmitoleylation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // non-traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0015026 // coreceptor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042289 // MHC class II protein binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 216425_at AK026465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026465.1 /DEF=Homo sapiens cDNA: FLJ22812 fis, clone KAIA2955. /FEA=mRNA /DB_XREF=gi:10439335 /UG=Hs.306853 Homo sapiens cDNA: FLJ22812 fis, clone KAIA2955 AK026465 216426_at AL136318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136318 /DEF=Human DNA sequence from clone RP1-254P11 on chromosome 10 Contains ESTs, STSs and GSSs. Contains a gene for a novel protein similar to RNA polymerase II elongation factor SIII, subunit P15 /FEA=mRNA /DB_XREF=gi:9369005 /UG=Hs.287783 Human DNA sequence from clone RP1-254P11 on chromosome 10 Contains ESTs, STSs and GSSs. Contains a gene for a novel protein similar to RNA polymerase II elongation factor SIII, subunit P15 AL136318 transcription elongation factor B (SIII), polypeptide 1 pseudogene 3 /// TCEB1P3 /// TCEB1P3 216427_at AK026439 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026439.1 /DEF=Homo sapiens cDNA: FLJ22786 fis, clone KAIA2150. /FEA=mRNA /DB_XREF=gi:10439304 /UG=Hs.306848 Homo sapiens cDNA: FLJ22786 fis, clone KAIA2150 AK026439 216428_x_at AK024467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024467.1 /DEF=Homo sapiens mRNA for FLJ00060 protein, partial cds. /FEA=mRNA /GEN=FLJ00060 /PROD=FLJ00060 protein /DB_XREF=gi:10440447 /UG=Hs.288520 Homo sapiens mRNA for FLJ00060 protein, partial cds AK024467 killer cell immunoglobulin-like receptor, three domains, X1 KIR3DX1 90011 NM_001047605 /// NM_033206 /// NR_026716 /// NR_104095 /// NR_104096 /// NR_104097 0005576 // extracellular region // inferred from electronic annotation 216429_at AK025422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025422.1 /DEF=Homo sapiens cDNA: FLJ21769 fis, clone COLF7354. /FEA=mRNA /DB_XREF=gi:10437930 /UG=Hs.306810 Homo sapiens cDNA: FLJ21769 fis, clone COLF7354 AK025422 216430_x_at AF043586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043586.1 /DEF=Homo sapiens clone CPRF1-T2 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865483 /UG=Hs.287816 Homo sapiens clone CPRF1-T2 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043586 immunoglobulin lambda variable 1-44 IGLV1-44 28823 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216431_at AK025363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025363.1 /DEF=Homo sapiens cDNA: FLJ21710 fis, clone COL10087. /FEA=mRNA /DB_XREF=gi:10437865 /UG=Hs.306807 Homo sapiens cDNA: FLJ21710 fis, clone COL10087 AK025363 216432_at AK025121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025121.1 /DEF=Homo sapiens cDNA: FLJ21468 fis, clone COL04875, highly similar to HSU84392 Human Na+-dependent purine specific transporter mRNA. /FEA=mRNA /DB_XREF=gi:10437574 /UG=Hs.306770 Homo sapiens cDNA: FLJ21468 fis, clone COL04875, highly similar to HSU84392 Human Na+-dependent purine specific transporter mRNA AK025121 solute carrier family 28 (concentrative nucleoside transporter), member 2 SLC28A2 9153 NM_004212 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015860 // purine nucleoside transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0001882 // nucleoside binding // inferred from electronic annotation /// 0005415 // nucleoside:sodium symporter activity // inferred from electronic annotation /// 0015211 // purine nucleoside transmembrane transporter activity // traceable author statement 216433_s_at U23736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U23736.1 /DEF=Human GATA-3 binding protein G3B mRNA, partial cds. /FEA=mRNA /PROD=GATA-3 binding protein G3B /DB_XREF=gi:915214 /UG=Hs.289024 PR domain containing 2, with ZNF domain U23736 PR domain containing 2, with ZNF domain PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216434_at AK025188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025188.1 /DEF=Homo sapiens cDNA: FLJ21535 fis, clone COL06131. /FEA=mRNA /DB_XREF=gi:10437651 /UG=Hs.306781 Homo sapiens cDNA: FLJ21535 fis, clone COL06131 AK025188 tetratricopeptide repeat domain 38 TTC38 55020 NM_017931 /// XR_244380 216435_at AK025177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025177.1 /DEF=Homo sapiens cDNA: FLJ21524 fis, clone COL05921. /FEA=mRNA /DB_XREF=gi:10437640 /UG=Hs.306778 Homo sapiens cDNA: FLJ21524 fis, clone COL05921 AK025177 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216436_at AK025026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025026.1 /DEF=Homo sapiens cDNA: FLJ21373 fis, clone COL03214. /FEA=mRNA /DB_XREF=gi:10437461 /UG=Hs.306747 Homo sapiens cDNA: FLJ21373 fis, clone COL03214 AK025026 phosphoinositide-3-kinase, regulatory subunit 4 PIK3R4 30849 NM_014602 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216437_at AK024949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024949.1 /DEF=Homo sapiens cDNA: FLJ21296 fis, clone COL02029. /FEA=mRNA /DB_XREF=gi:10437372 /UG=Hs.306734 Homo sapiens cDNA: FLJ21296 fis, clone COL02029 AK024949 216438_s_at AL133228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133228 /DEF=Human DNA sequence from clone RP5-1071L10 on chromosome 20 Contains part of a gene for a new member of the thymosininterferon-inducible multigene family, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:8217426 /UG=Hs.288031 sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like AL133228 thymosin beta 4, X-linked TMSB4X 7114 NM_021109 0002576 // platelet degranulation // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042989 // sequestering of actin monomers // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216439_at AK024904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024904.1 /DEF=Homo sapiens cDNA: FLJ21251 fis, clone COL01259. /FEA=mRNA /DB_XREF=gi:10437318 /UG=Hs.306722 Homo sapiens cDNA: FLJ21251 fis, clone COL01259 AK024904 tyrosine kinase, non-receptor, 2 TNK2 10188 NM_001010938 /// NM_005781 /// XM_005269268 /// XM_005269269 /// XM_005269270 /// XM_005269271 /// XM_005269272 /// XM_005269273 /// XM_005269274 /// XM_005269275 /// XM_006713460 /// XM_006713461 /// XM_006713462 /// XM_006713463 /// XM_006713464 /// XM_006713465 /// XM_006713466 /// XM_006713467 /// XM_006713468 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070436 // Grb2-EGFR complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from sequence or structural similarity 216440_at AK024868 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024868.1 /DEF=Homo sapiens cDNA: FLJ21215 fis, clone COL00526. /FEA=mRNA /DB_XREF=gi:10437278 /UG=Hs.306711 Homo sapiens cDNA: FLJ21215 fis, clone COL00526 AK024868 216441_at AK025573 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025573.1 /DEF=Homo sapiens cDNA: FLJ21920 fis, clone HEP04049. /FEA=mRNA /DB_XREF=gi:10438129 /UG=Hs.288025 Homo sapiens cDNA: FLJ21920 fis, clone HEP04049 AK025573 216442_x_at AK026737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026737.1 /DEF=Homo sapiens cDNA: FLJ23084 fis, clone LNG06602, highly similar to HSFIB1 Human mRNA for fibronectin (FN precursor). /FEA=mRNA /DB_XREF=gi:10439658 /UG=Hs.287820 fibronectin 1 AK026737 fibronectin 1 FN1 2335 NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation 216443_at AK024615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024615.1 /DEF=Homo sapiens cDNA: FLJ20962 fis, clone ADSH00804. /FEA=mRNA /DB_XREF=gi:10436931 /UG=Hs.306698 Homo sapiens cDNA: FLJ20962 fis, clone ADSH00804 AK024615 216444_at AK024138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024138.1 /DEF=Homo sapiens cDNA FLJ14076 fis, clone HEMBB1001925. /FEA=mRNA /DB_XREF=gi:10436445 /UG=Hs.306667 Homo sapiens cDNA FLJ14076 fis, clone HEMBB1001925 AK024138 216445_at U23736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U23736.1 /DEF=Human GATA-3 binding protein G3B mRNA, partial cds. /FEA=mRNA /PROD=GATA-3 binding protein G3B /DB_XREF=gi:915214 /UG=Hs.289024 PR domain containing 2, with ZNF domain U23736 216446_at AK024568 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024568.1 /DEF=Homo sapiens cDNA: FLJ20915 fis, clone ADSE00692. /FEA=mRNA /DB_XREF=gi:10436878 /UG=Hs.306691 Homo sapiens cDNA: FLJ20915 fis, clone ADSE00692 AK024568 216447_at AK024525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024525.1 /DEF=Homo sapiens cDNA: FLJ20872 fis, clone ADKA02604. /FEA=mRNA /DB_XREF=gi:10436827 /UG=Hs.306683 Homo sapiens cDNA: FLJ20872 fis, clone ADKA02604 AK024525 216448_at AK022686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022686.1 /DEF=Homo sapiens cDNA FLJ12624 fis, clone NT2RM4001754. /FEA=mRNA /DB_XREF=gi:10434225 /UG=Hs.306639 Homo sapiens cDNA FLJ12624 fis, clone NT2RM4001754 AK022686 216449_x_at AK025862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025862.1 /DEF=Homo sapiens cDNA: FLJ22209 fis, clone HRC01496. /FEA=mRNA /DB_XREF=gi:10438505 /UG=Hs.288528 Homo sapiens cDNA: FLJ22209 fis, clone HRC01496 AK025862 heat shock protein 90kDa beta (Grp94), member 1 HSP90B1 7184 NM_003299 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 216450_x_at AK025862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025862.1 /DEF=Homo sapiens cDNA: FLJ22209 fis, clone HRC01496. /FEA=mRNA /DB_XREF=gi:10438505 /UG=Hs.288528 Homo sapiens cDNA: FLJ22209 fis, clone HRC01496 AK025862 heat shock protein 90kDa beta (Grp94), member 1 HSP90B1 7184 NM_003299 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 216451_at AF034187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF034187.1 /DEF=Homo sapiens clone 2.2H12 Ndr SerThr kinase-like protein mRNA, partial cds. /FEA=mRNA /PROD=Ndr SerThr kinase-like protein /DB_XREF=gi:5757628 /UG=Hs.306543 Homo sapiens clone 2.2H12 Ndr SerThr kinase-like protein mRNA, partial cds AF034187 serine/threonine kinase 38 STK38 11329 NM_007271 /// XM_005248839 /// XM_006714988 /// XM_006714989 /// XM_006714990 0006464 // cellular protein modification process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216452_at AB046836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046836.1 /DEF=Homo sapiens mRNA for KIAA1616 protein, partial cds. /FEA=mRNA /GEN=KIAA1616 /PROD=KIAA1616 protein /DB_XREF=gi:10047308 /UG=Hs.288911 KIAA1616 protein AB046836 transient receptor potential cation channel, subfamily M, member 3 TRPM3 80036 NM_001007470 /// NM_001007471 /// NM_020952 /// NM_024971 /// NM_206944 /// NM_206945 /// NM_206946 /// NM_206947 /// NM_206948 /// XM_005252218 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation 216453_at AL359578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359578.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547N163 (from clone DKFZp547N163). /FEA=mRNA /DB_XREF=gi:8655637 /UG=Hs.306511 Homo sapiens mRNA; cDNA DKFZp547N163 (from clone DKFZp547N163) AL359578 zinc finger protein 287 ZNF287 57336 NM_020653 /// XM_005256743 /// XM_006721561 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // /// 0006366 // transcription from RNA polymerase II promoter // /// 0014003 // oligodendrocyte development // /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216454_at AL390133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390133.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547I147 (from clone DKFZp547I147). /FEA=mRNA /DB_XREF=gi:9368829 /UG=Hs.306518 Homo sapiens mRNA; cDNA DKFZp547I147 (from clone DKFZp547I147) AL390133 tRNA methyltransferase 1 homolog (S. cerevisiae) TRMT1 55621 NM_001136035 /// NM_001142554 /// NM_017722 /// XM_005259983 /// XM_006722793 /// XM_006722794 0030488 // tRNA methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0004809 // tRNA (guanine-N2-)-methyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216455_at AK024457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024457.1 /DEF=Homo sapiens mRNA for FLJ00049 protein, partial cds. /FEA=mRNA /GEN=FLJ00049 /PROD=FLJ00049 protein /DB_XREF=gi:10440427 /UG=Hs.288853 Homo sapiens mRNA for FLJ00049 protein, partial cds AK024457 216456_at AL162044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162044.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L0812 (from clone DKFZp761L0812); partial cds. /FEA=mRNA /GEN=DKFZp761L0812 /PROD=hypothetical protein /DB_XREF=gi:7328083 /UG=Hs.306494 Homo sapiens mRNA; cDNA DKFZp761L0812 (from clone DKFZp761L0812); partial cds AL162044 216457_s_at AK026080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026080.1 /DEF=Homo sapiens cDNA: FLJ22427 fis, clone HRC09013. /FEA=mRNA /DB_XREF=gi:10438814 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD AK026080 splicing factor 3a, subunit 1, 120kDa SF3A1 10291 NM_001005409 /// NM_005877 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005684 // U2-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216458_at AL161956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161956.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761A17121 (from clone DKFZp761A17121). /FEA=mRNA /DB_XREF=gi:7328008 /UG=Hs.306492 Homo sapiens mRNA; cDNA DKFZp761A17121 (from clone DKFZp761A17121) AL161956 PQ loop repeat containing 3 PQLC3 130814 NM_001282710 /// NM_001282711 /// NM_001282712 /// NM_152391 /// NR_104231 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216459_x_at AL137624 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137624.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M1812 (from clone DKFZp434M1812). /FEA=mRNA /DB_XREF=gi:6808420 /UG=Hs.306476 Homo sapiens mRNA; cDNA DKFZp434M1812 (from clone DKFZp434M1812) AL137624 DDR1 antisense RNA 1 (head to head) DDR1-AS1 414771 216460_at AK024457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024457.1 /DEF=Homo sapiens mRNA for FLJ00049 protein, partial cds. /FEA=mRNA /GEN=FLJ00049 /PROD=FLJ00049 protein /DB_XREF=gi:10440427 /UG=Hs.288853 Homo sapiens mRNA for FLJ00049 protein, partial cds AK024457 uncharacterized LOC101927181 LOC101927181 101927181 NR_108066 216461_at AK000834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000834.1 /DEF=Homo sapiens cDNA FLJ20827 fis, clone ADKA03543. /FEA=mRNA /DB_XREF=gi:7021152 /UG=Hs.306409 Homo sapiens cDNA FLJ20827 fis, clone ADKA03543 AK000834 216462_at X79200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79200.1 /DEF=Homo spaiens mRNA for SYT-SSX protein. /FEA=mRNA /PROD=SYT-SSX protein /DB_XREF=gi:531107 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 X79200 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 216463_at AL117520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117520.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P2435 (from clone DKFZp434P2435). /FEA=mRNA /DB_XREF=gi:5912036 /UG=Hs.306348 Homo sapiens mRNA; cDNA DKFZp434P2435 (from clone DKFZp434P2435) AL117520 216464_x_at AF118265 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF118265 /DEF=Homo sapiens orphan G protein-coupled receptor GPR44 (GPR44) gene, complete cds /FEA=CDS /DB_XREF=gi:4455060 /UG=Hs.299567 G protein-coupled receptor 44 AF118265 prostaglandin D2 receptor 2 PTGDR2 11251 NM_004778 0006935 // chemotaxis // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001785 // prostaglandin J receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0004956 // prostaglandin D receptor activity // inferred from direct assay /// 0004958 // prostaglandin F receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 216465_at AL110206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110206.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N2022 (from clone DKFZp586N2022). /FEA=mRNA /DB_XREF=gi:5817125 /UG=Hs.306339 Homo sapiens mRNA; cDNA DKFZp586N2022 (from clone DKFZp586N2022) AL110206 216466_at AL080104 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080104.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566D153 (from clone DKFZp566D153). /FEA=mRNA /DB_XREF=gi:5262529 /UG=Hs.306322 Homo sapiens mRNA; cDNA DKFZp566D153 (from clone DKFZp566D153) AL080104 neuron navigator 3 NAV3 89795 NM_001024383 /// NM_014903 /// XM_005269215 /// XM_006719675 /// XM_006719676 /// XM_006719677 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 216467_s_at AL049997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049997.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564L102 (from clone DKFZp564L102). /FEA=mRNA /DB_XREF=gi:4884250 /UG=Hs.306305 Homo sapiens mRNA; cDNA DKFZp564L102 (from clone DKFZp564L102) AL049997 216468_s_at AC006539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006539 /DEF=Homo sapiens chromosome 19, BAC 39498 (CIT-B-26L23) /FEA=CDS_1 /DB_XREF=gi:4235141 /UG=Hs.306298 Homo sapiens chromosome 19, BAC 39498 (CIT-B-26L23) AC006539 zinc finger protein 682 ZNF682 91120 NM_001077349 /// NM_033196 /// XM_005260146 /// XM_005260147 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216469_at AL163202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL163202 /DEF=Homo sapiens chromosome 21 segment HS21C002 /FEA=CDS /DB_XREF=gi:7717242 /UG=Hs.289121 Homo sapiens chromosome 21 segment HS21C002 AL163202 putative zinc finger protein ENSP00000328166-like /// zinc finger protein 91 pseudogene LOC102725136 /// LOC441666 441666 /// 102725136 NR_024380 /// XM_006726809 216470_x_at AF009664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009664 /DEF=Homo sapiens T cell receptor beta locus, 3 trypsinogen repeats /FEA=CDS_1 /DB_XREF=gi:2275594 /UG=Hs.303157 T cell receptor beta locus AF009664 protease, serine, 2 (trypsin 2) PRSS2 5645 NM_002770 /// XM_005276996 /// XM_005276998 /// XM_006716052 /// XM_006716053 /// XM_006725058 0006508 // proteolysis // inferred from direct assay /// 0007586 // digestion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216471_x_at X79200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79200.1 /DEF=Homo spaiens mRNA for SYT-SSX protein. /FEA=mRNA /PROD=SYT-SSX protein /DB_XREF=gi:531107 /UG=Hs.289105 synovial sarcoma, X breakpoint 2 X79200 synovial sarcoma, X breakpoint 2 /// synovial sarcoma, X breakpoint 2B SSX2 /// SSX2B 6757 /// 727837 NM_001164417 /// NM_001278697 /// NM_001278701 /// NM_001278702 /// NM_003147 /// NM_175698 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 216472_at AF003737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF003737.1 /DEF=Homo sapiens chromosome 21q22.1 anonymous mRNA sequence. /FEA=mRNA /DB_XREF=gi:2197086 /UG=Hs.302179 Homo sapiens chromosome 21q22.1 anonymous mRNA sequence AF003737 216473_x_at D38024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38024 /DEF=Human facioscapulohumeral muscular dystrophy (FSHD) gene region, D4Z4 tandem repeat unit /FEA=CDS /DB_XREF=gi:871846 /UG=Hs.296821 Human facioscapulohumeral muscular dystrophy (FSHD) gene region, D4Z4 tandem repeat unit D38024 D4Z4 binding element transcript (non-protein coding) /// double homeobox 4 /// double homeobox 4 like 1 /// double homeobox 4 like 2 /// double homeobox 4 like 24 /// double homeobox 4 like 3 /// double homeobox 4 like 4 /// double homeobox 4 like 5 /// double homeobox 4 like 6 /// double homeobox 4 like 7 /// double homeobox 4 like 8 /// double homeobox protein 4-like protein 2-like /// double homeobox protein 4-like /// double homeobox protein 4-like protein 4-like DBET /// DUX4 /// DUX4L1 /// DUX4L2 /// DUX4L24 /// DUX4L3 /// DUX4L4 /// DUX4L5 /// DUX4L6 /// DUX4L7 /// DUX4L8 /// LOC100288289 /// LOC100291626 /// LOC652301 22947 /// 26583 /// 441056 /// 652301 /// 653543 /// 653544 /// 653545 /// 653548 /// 728410 /// 100288289 /// 100288687 /// 100291626 /// 100419743 /// 102723449 NM_001127386 /// NM_001127387 /// NM_001127388 /// NM_001127389 /// NM_001164467 /// NM_001177376 /// NM_001205218 /// NM_001278056 /// NM_001293798 /// NM_012147 /// NM_033178 /// NR_033487 /// NR_038191 /// NR_121644 /// XM_005276047 /// XM_005276087 /// XM_006710245 /// XM_006718103 /// XM_006726416 /// XM_006726525 /// XR_426490 /// XR_431831 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0070317 // negative regulation of G0 to G1 transition // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216474_x_at AF206667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF206667.1 /DEF=Homo sapiens mast cell beta I tryptase mRNA, partial cds, alternatively spliced. /FEA=mRNA /PROD=mast cell beta I tryptase /DB_XREF=gi:11493901 /UG=Hs.294158 tryptase beta 2 AF206667 tryptase alpha/beta 1 /// tryptase beta 2 (gene/pseudogene) TPSAB1 /// TPSB2 7177 /// 64499 NM_003294 /// NM_024164 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 216475_at AL133269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133269 /DEF=Human DNA sequence from clone RP3-468K3 on chromosome 6q25-26. Contains a beta tubulin pseudogene, STSs and GSSs /FEA=CDS /DB_XREF=gi:9662888 /UG=Hs.302112 Human DNA sequence from clone RP3-468K3 on chromosome 6q25-26. Contains a beta tubulin pseudogene, STSs and GSSs AL133269 tubulin, beta 4B class IVb pseudogene 7 /// TUBB4BP7 /// TUBB4BP7 216476_at AL353580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353580 /DEF=Human DNA sequence from clone RP11-248N6 on chromosome 13 Contains ESTs, STSs and GSSs. Contains two olfactory receptor pseudogenes, an NPM1 (nucleophosmin, nucleolar phosphoprotein B23, numatrin) pseudogene and a BCR (breakpoint cluster region) p... /FEA=CDS_1 /DB_XREF=gi:9944152 /UG=Hs.302100 Human DNA sequence from clone RP11-248N6 on chromosome 13 Contains ESTs, STSs and GSSs. Contains two olfactory receptor pseudogenes, an NPM1 (nucleophosmin, nucleolar phosphoprotein B23, numatrin) pseudogene and a BCR (breakpoint cluster region) pseudogen AL353580 olfactory receptor, family 7, subfamily E, member 111 pseudogene /// OR7E111P /// OR7E111P 216477_at AL157837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157837 /DEF=Human DNA sequence from clone RP11-467I21 on chromosome 1q31.1-31.3 Contains a ribosomal protein L23A pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9801319 /UG=Hs.302083 Human DNA sequence from clone RP11-467I21 on chromosome 1q31.1-31.3 Contains a ribosomal protein L23A pseudogene, ESTs, STSs and GSSs AL157837 ribosomal protein L23a pseudogene 22 /// RPL23AP22 /// RPL23AP22 216478_at AL049252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049252.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D193 (from clone DKFZp564D193). /FEA=mRNA /DB_XREF=gi:4499993 /UG=Hs.302048 Homo sapiens mRNA; cDNA DKFZp564D193 (from clone DKFZp564D193) AL049252 216479_at AL356414 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL356414 /DEF=Human DNA sequence from clone RP11-352D3 on chromosome 20 Contains a 60S ribosomal protein L21 (RPL21) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:10045426 /UG=Hs.296782 Human DNA sequence from clone RP11-352D3 on chromosome 20 Contains a 60S ribosomal protein L21 (RPL21) pseudogene, ESTs, STSs and GSSs AL356414 ribosomal protein L21 /// ribosomal protein L21 pseudogene 28 /// small nucleolar RNA, H/ACA box 27 /// small nucleolar RNA, C/D box 102 RPL21 /// RPL21P28 /// SNORA27 /// SNORD102 6144 /// 26771 /// 619499 /// 100131205 NM_000982 /// NR_002574 /// NR_002575 /// NR_026911 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 216480_x_at AF060927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF060927.1 /DEF=Homo sapiens type I AF10CALM fusion protein (AF10CALM) mRNA, partial cds. /FEA=mRNA /GEN=AF10CALM /PROD=type I AF10CALM fusion protein /DB_XREF=gi:3139004 /UG=Hs.301209 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 AF060927 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 MLLT10 8028 NM_001009569 /// NM_001195626 /// NM_001195627 /// NM_001195628 /// NM_001195630 /// NM_004641 /// XM_005252605 /// XM_005252606 /// XM_005252608 /// XM_005252609 /// XM_005252610 /// XM_005252611 /// XM_005252612 /// XM_006717509 /// XR_428648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216481_at AF052177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052177.1 /DEF=Homo sapiens clone 24510 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360488 /UG=Hs.296770 KIAA1719 protein AF052177 glutamate receptor interacting protein 2 GRIP2 80852 NM_001080423 0007268 // synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 216482_x_at X65232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X65232.1 /DEF=H.sapiens mRNA for Zinc-finger protein (ZNFpT7). /FEA=mRNA /PROD=zinc-finger protein (ZNFpT7) /DB_XREF=gi:505547 /UG=Hs.301114 zinc finger protein 79 (pT7) X65232 zinc finger protein 79 ZNF79 7633 NM_001286696 /// NM_001286697 /// NM_001286698 /// NM_007135 /// XM_006717279 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216483_s_at AC005339 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005339 /DEF=Homo sapiens chromosome 19, cosmid R33729 /FEA=CDS /DB_XREF=gi:3355454 /UG=Hs.296443 hypothetical protein R33729_1 AC005339 chromosome 19 open reading frame 10 C19orf10 56005 NM_019107 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 216484_x_at L24521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L24521.1 /DEF=Human transformation-related protein mRNA, 3 end. /FEA=mRNA /PROD=transformation-related protein /DB_XREF=gi:403459 /UG=Hs.300705 Human transformation-related protein mRNA, 3 end L24521 216485_s_at AF206667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF206667.1 /DEF=Homo sapiens mast cell beta I tryptase mRNA, partial cds, alternatively spliced. /FEA=mRNA /PROD=mast cell beta I tryptase /DB_XREF=gi:11493901 /UG=Hs.294158 tryptase beta 2 AF206667 tryptase alpha/beta 1 TPSAB1 7177 NM_003294 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 216486_x_at X65232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X65232.1 /DEF=H.sapiens mRNA for Zinc-finger protein (ZNFpT7). /FEA=mRNA /PROD=zinc-finger protein (ZNFpT7) /DB_XREF=gi:505547 /UG=Hs.301114 zinc finger protein 79 (pT7) X65232 zinc finger protein 79 ZNF79 7633 NM_001286696 /// NM_001286697 /// NM_001286698 /// NM_007135 /// XM_006717279 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216487_at AL049988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049988.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F212 (from clone DKFZp564F212). /FEA=mRNA /DB_XREF=gi:4884239 /UG=Hs.306304 Homo sapiens mRNA; cDNA DKFZp564F212 (from clone DKFZp564F212) AL049988 216488_s_at AL161996 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161996.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P0831 (from clone DKFZp434P0831). /FEA=mRNA /DB_XREF=gi:7328131 /UG=Hs.29189 ATPase, Class VI, type 11A AL161996 ATPase, class VI, type 11A ATP11A 23250 NM_015205 /// NM_032189 /// XM_005268299 /// XM_005268300 /// XM_005268301 /// XM_005268303 /// XM_005268305 /// XM_005268306 /// XM_006719965 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216489_at AB046836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046836.1 /DEF=Homo sapiens mRNA for KIAA1616 protein, partial cds. /FEA=mRNA /GEN=KIAA1616 /PROD=KIAA1616 protein /DB_XREF=gi:10047308 /UG=Hs.288911 KIAA1616 protein AB046836 uncharacterized LOC101927086 LOC101927086 101927086 XR_242612 /// XR_250472 /// XR_252581 /// XR_428546 216490_x_at AL133267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133267 /DEF=Human DNA sequence from clone RP3-408B20 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a gene and two pseudogenes for novel 7 transmembrane receptors (olfactory family) and a gene for a novel protein similar to 60S acidic ribosomal protei... /FEA=CDS_2 /DB_XREF=gi:10185396 /UG=Hs.302087 Human DNA sequence from clone RP3-408B20 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a gene and two pseudogenes for novel 7 transmembrane receptors (olfactory family) and a gene for a novel protein similar to 60S acidic ribosomal protein P2 (RP AL133267 ribosomal protein, large P2, pseudogene 1 /// RPLP2P1 /// RPLP2P1 216491_x_at U80139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80139 /DEF=Human immunoglobulin heavy chain variable region (V4-4) gene, partial cds /FEA=CDS /DB_XREF=gi:1791120 /UG=Hs.288711 Human immunoglobulin heavy chain variable region (V4-4) gene, partial cds U80139 immunoglobulin heavy constant mu IGHM 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216492_at AK024467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024467.1 /DEF=Homo sapiens mRNA for FLJ00060 protein, partial cds. /FEA=mRNA /GEN=FLJ00060 /PROD=FLJ00060 protein /DB_XREF=gi:10440447 /UG=Hs.288520 Homo sapiens mRNA for FLJ00060 protein, partial cds AK024467 killer cell immunoglobulin-like receptor, three domains, X1 KIR3DX1 90011 NM_001047605 /// NM_033206 /// NR_026716 /// NR_104095 /// NR_104096 /// NR_104097 0005576 // extracellular region // inferred from electronic annotation 216493_s_at AL023775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023775 /DEF=Human DNA sequence from clone 497J21 on chromosome 6q26-27. Contains a KOC (KH-domain containg transcript overexpressed in cancer) pseudogene, genomic marker D6S193, ESTs, STSs and GSSs, and a ca repeat polymorphism /FEA=CDS /DB_XREF=gi:3646096 /UG=Hs.300813 Human DNA sequence from clone 497J21 on chromosome 6q26-27. Contains a KOC (KH-domain containg transcript overexpressed in cancer) pseudogene, genomic marker D6S193, ESTs, STSs and GSSs, and a ca repeat polymorphism AL023775 insulin-like growth factor 2 mRNA binding protein 3 IGF2BP3 10643 NM_006547 /// XM_006715638 /// XM_006715639 0006412 // translation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 216494_at AL023775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023775 /DEF=Human DNA sequence from clone 497J21 on chromosome 6q26-27. Contains a KOC (KH-domain containg transcript overexpressed in cancer) pseudogene, genomic marker D6S193, ESTs, STSs and GSSs, and a ca repeat polymorphism /FEA=CDS /DB_XREF=gi:3646096 /UG=Hs.300813 Human DNA sequence from clone 497J21 on chromosome 6q26-27. Contains a KOC (KH-domain containg transcript overexpressed in cancer) pseudogene, genomic marker D6S193, ESTs, STSs and GSSs, and a ca repeat polymorphism AL023775 RP3-497J21.1 216495_x_at AF043584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043584.1 /DEF=Homo sapiens clone ASMneg1-b1 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865479 /UG=Hs.287815 Homo sapiens clone ASMneg1-b1 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043584 216496_s_at AK021988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021988.1 /DEF=Homo sapiens cDNA FLJ11926 fis, clone HEMBB1000374. /FEA=mRNA /DB_XREF=gi:10433297 /UG=Hs.306617 Homo sapiens cDNA FLJ11926 fis, clone HEMBB1000374 AK021988 216497_at AL390738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390738 /DEF=Human DNA sequence from clone RP11-438F9 on chromosome 13 Contains the gene for the ortholog of mouse homeobox protein GSH1, the 3 end of the gene for a novel protein similar to heterogeneous nuclear ribonucleoprotein A1 (HNRPA1), ESTs, STSs, GSS... /FEA=mRNA_2 /DB_XREF=gi:9650602 /UG=Hs.287788 Human DNA sequence from clone RP11-438F9 on chromosome 13 Contains the gene for the ortholog of mouse homeobox protein GSH1, the 3 end of the gene for a novel protein similar to heterogeneous nuclear ribonucleoprotein A1 (HNRPA1), ESTs, STSs, GSSs and th AL390738 216498_at AL390026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390026 /DEF=Human DNA sequence from clone RP3-336K20 on chromosome 6 Contains parts of 2 genes for novel proteins, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9368311 /UG=Hs.287777 Human DNA sequence from clone RP3-336K20 on chromosome 6 Contains parts of 2 genes for novel proteins, ESTs, STSs and GSSs AL390026 RP3-336K20__B.2 216499_at AL137590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137590.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K0610 (from clone DKFZp434K0610). /FEA=mRNA /DB_XREF=gi:6808330 /UG=Hs.300785 Homo sapiens mRNA; cDNA DKFZp434K0610 (from clone DKFZp434K0610) AL137590 uncharacterized LOC102723620 LOC102723620 102723620 XR_426014 /// XR_427916 216500_at M14087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M14087.1 /DEF=Human HL14 gene encoding beta-galactoside-binding lectin, 3 end, clone 2. /FEA=mRNA /DB_XREF=gi:187113 /UG=Hs.287389 Human HL14 gene encoding beta-galactoside-binding lectin, 3 end, clone 2 M14087 0002317 // plasma cell differentiation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from direct assay /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034120 // positive regulation of erythrocyte aggregation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // non-traceable author statement /// 0016936 // galactoside binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030395 // lactose binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation 216501_at U25801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U25801.1 /DEF=Human Tax1 binding protein mRNA, partial cds. /FEA=mRNA /PROD=Tax1 binding protein /DB_XREF=gi:1122440 /UG=Hs.287365 Tax1 (human T-cell leukemia virus type I) binding protein 1 U25801 Vac14 homolog (S. cerevisiae) VAC14 55697 NM_018052 /// XM_005256038 /// XM_005256039 /// XM_005256040 /// XM_005256041 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070772 // PAS complex // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 216502_at AL096734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096734.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M011 (from clone DKFZp434M011). /FEA=mRNA /DB_XREF=gi:5419867 /UG=Hs.301904 Homo sapiens, Similar to hypothetical protein FLJ12484, clone MGC:3008, mRNA, complete cds AL096734 interferon stimulated exonuclease gene 20kDa-like 2 ISG20L2 81875 NM_030980 /// XM_005245516 /// XM_005245517 /// XM_005245518 /// XM_006711560 /// XM_006711561 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216503_s_at AF060927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF060927.1 /DEF=Homo sapiens type I AF10CALM fusion protein (AF10CALM) mRNA, partial cds. /FEA=mRNA /GEN=AF10CALM /PROD=type I AF10CALM fusion protein /DB_XREF=gi:3139004 /UG=Hs.301209 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 AF060927 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 MLLT10 8028 NM_001009569 /// NM_001195626 /// NM_001195627 /// NM_001195628 /// NM_001195630 /// NM_004641 /// XM_005252605 /// XM_005252606 /// XM_005252608 /// XM_005252609 /// XM_005252610 /// XM_005252611 /// XM_005252612 /// XM_006717509 /// XR_428648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216504_s_at AL049963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049963.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A132 (from clone DKFZp564A132). /FEA=mRNA /DB_XREF=gi:4884213 /UG=Hs.284205 up-regulated by BCG-CWS AL049963 solute carrier family 39 (zinc transporter), member 8 SLC39A8 64116 NM_001135146 /// NM_001135147 /// NM_001135148 /// NM_022154 /// XM_005263177 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from mutant phenotype /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from direct assay 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 216505_x_at AL118502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL118502 /DEF=Human DNA sequence from clone RP11-371L19 on chromosome 20 Contains a novel gene, a gene similar to the gene for ribosomal protein S10, ESTs, STSs, GSSs and CpG islands /FEA=mRNA_3 /DB_XREF=gi:8894621 /UG=Hs.284299 Human DNA sequence from clone RP11-371L19 on chromosome 20 Contains a novel gene, a gene similar to the gene for ribosomal protein S10, ESTs, STSs, GSSs and CpG islands AL118502 RPS10L 216506_x_at AF060938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF060938.1 /DEF=Homo sapiens type V AF10 protein (AF10) mRNA, partial cds. /FEA=mRNA /GEN=AF10 /PROD=type V AF10 protein /DB_XREF=gi:3139026 /UG=Hs.301209 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 AF060938 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 MLLT10 8028 NM_001009569 /// NM_001195626 /// NM_001195627 /// NM_001195628 /// NM_001195630 /// NM_004641 /// XM_005252605 /// XM_005252606 /// XM_005252608 /// XM_005252609 /// XM_005252610 /// XM_005252611 /// XM_005252612 /// XM_006717509 /// XR_428648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216507_at AF189251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF189251.1 /DEF=Homo sapiens cytomegalovirus partial fusion receptor mRNA, partial cds. /FEA=mRNA /PROD=cytomegalovirus partial fusion receptor /DB_XREF=gi:6760349 /UG=Hs.283927 Homo sapiens cytomegalovirus partial fusion receptor mRNA, partial cds AF189251 transmembrane anterior posterior transformation 1 TAPT1 202018 NM_153365 /// XM_005248139 /// XM_005248140 /// XM_005248141 /// XM_005248142 /// XR_241676 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0016520 // growth hormone-releasing hormone receptor activity // traceable author statement 216508_x_at AC007277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007277 /DEF=Homo sapiens BAC clone RP11-244E6 from 2 /FEA=CDS /DB_XREF=gi:5091647 /UG=Hs.283906 Homo sapiens BAC clone RP11-244E6 from 2 AC007277 high mobility group box 1 pseudogene 4 /// HMGB1P4 /// HMGB1P4 216509_x_at AF060938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF060938.1 /DEF=Homo sapiens type V AF10 protein (AF10) mRNA, partial cds. /FEA=mRNA /GEN=AF10 /PROD=type V AF10 protein /DB_XREF=gi:3139026 /UG=Hs.301209 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 10 AF060938 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 MLLT10 8028 NM_001009569 /// NM_001195626 /// NM_001195627 /// NM_001195628 /// NM_001195630 /// NM_004641 /// XM_005252605 /// XM_005252606 /// XM_005252608 /// XM_005252609 /// XM_005252610 /// XM_005252611 /// XM_005252612 /// XM_006717509 /// XR_428648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216510_x_at AB035175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB035175 /DEF=Homo sapiens IgH VH gene for immunoglobulin heavy chain, partial cds /FEA=CDS /DB_XREF=gi:6683513 /UG=Hs.301365 Human rearranged immunoglobulin heavy chain mRNA, partial cds AB035175 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 3-23 /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHG1 /// IGHM /// IGHV3-23 /// IGHV4-31 3493 /// 3500 /// 3507 /// 28396 /// 28442 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216511_s_at AJ270770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ270770 /DEF=Homo sapiens partial TCF-4 gene for T-cell transcription factor-4, exon 1 and joined CDS features /FEA=mRNA_1 /DB_XREF=gi:9188625 /UG=Hs.283857 Homo sapiens partial TCF-4 gene for T-cell transcription factor-4, exon 1 and joined CDS features AJ270770 transcription factor 7-like 2 (T-cell specific, HMG-box) TCF7L2 6934 NM_001146274 /// NM_001146283 /// NM_001146284 /// NM_001146285 /// NM_001146286 /// NM_001198525 /// NM_001198526 /// NM_001198527 /// NM_001198528 /// NM_001198529 /// NM_001198530 /// NM_001198531 /// NM_030756 /// XM_005270071 /// XM_005270073 /// XM_005270074 /// XM_005270075 /// XM_005270076 /// XM_005270077 /// XM_005270078 /// XM_005270079 /// XM_005270080 /// XM_005270082 /// XM_005270083 /// XM_005270084 /// XM_005270085 /// XM_005270086 /// XM_005270088 /// XM_005270089 /// XM_005270091 /// XM_005270092 /// XM_005270093 /// XM_005270094 /// XM_005270095 /// XM_005270096 /// XM_005270097 /// XM_005270098 /// XM_005270099 /// XM_005270100 /// XM_005270101 /// XM_005270102 /// XM_005270103 /// XM_005270104 /// XM_005270105 /// XM_006717955 /// XM_006717956 /// XM_006717957 /// XM_006717958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // not recorded /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030538 // embryonic genitalia morphogenesis // inferred from electronic annotation /// 0031016 // pancreas development // traceable author statement /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from direct assay /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032350 // regulation of hormone metabolic process // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048699 // generation of neurons // not recorded /// 0048713 // regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 216512_s_at AL139318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139318 /DEF=Human DNA sequence from clone RP11-124B17 on chromosome 13. Contains the DCT gene for dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), the 3 end of the gene for DTDP-D-glucose 4,6-dehydratase, ESTs, STSs, GSSs and ... /FEA=mRNA_2 /DB_XREF=gi:9800060 /UG=Hs.301865 dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) AL139318 dopachrome tautomerase DCT 1638 NM_001129889 /// NM_001922 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006583 // melanin biosynthetic process from tyrosine // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from sequence or structural similarity 0004167 // dopachrome isomerase activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216513_at AL139318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139318 /DEF=Human DNA sequence from clone RP11-124B17 on chromosome 13. Contains the DCT gene for dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), the 3 end of the gene for DTDP-D-glucose 4,6-dehydratase, ESTs, STSs, GSSs and ... /FEA=mRNA_2 /DB_XREF=gi:9800060 /UG=Hs.301865 dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) AL139318 dopachrome tautomerase DCT 1638 NM_001129889 /// NM_001922 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0006583 // melanin biosynthetic process from tyrosine // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from sequence or structural similarity 0004167 // dopachrome isomerase activity // inferred from sequence or structural similarity /// 0005507 // copper ion binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216514_at AF203728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF203728.1 /DEF=Homo sapiens bone morphogenetic protein BMPY (BMPY) mRNA, partial cds. /FEA=mRNA /GEN=BMPY /PROD=bone morphogenetic protein BMPY /DB_XREF=gi:6525028 /UG=Hs.283898 Homo sapiens bone morphogenetic protein BMPY (BMPY) mRNA, partial cds AF203728 0005576 // extracellular region // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 216515_x_at AL121585 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121585 /DEF=Human DNA sequence from clone RP11-504H3 on chromosome 20 Contains the SNX5 gene (sorting nexin 5), a gene similar to PTMA (prothymosin-alpha), the 3 end of a gene encoding a Zinc-finger protein, two CpG islands, ESTs, STSs and GSSs /FEA=mRNA_1 /DB_XREF=gi:8248733 /UG=Hs.283864 Human DNA sequence from clone RP11-504H3 on chromosome 20 Contains the SNX5 gene (sorting nexin 5), a gene similar to PTMA (prothymosin-alpha), the 3 end of a gene encoding a Zinc-finger protein, two CpG islands, ESTs, STSs and GSSs AL121585 microRNA 1244-3 MIR1244-3 100422872 NR_036263 216516_at AL080315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080315 /DEF=Human DNA sequence from clone RP1-6P5 on chromosome 6 Contains a pseudogene similar to EEF1D (eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)), a pseudogene similar to ribosomal protein L21, ESTs, STSs and GSSs /FEA=CDS_2 /DB_XREF=gi:7838240 /UG=Hs.283840 Human DNA sequence from clone RP1-6P5 on chromosome 6 Contains a pseudogene similar to EEF1D (eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)), a pseudogene similar to ribosomal protein L21, ESTs, STSs and GSSs AL080315 RP1-6P5.2 216517_at Z00008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z00008 /DEF=Human germline gene for the leader peptide and variable region of a kappa immunoglobulin (subgroup V kappa I) /FEA=CDS /DB_XREF=gi:33142 /UG=Hs.283770 immunoglobulin kappa variable 1D-8 Z00008 immunoglobulin kappa constant IGKC 3514 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216518_at AL049260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049260.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E233 (from clone DKFZp564E233). /FEA=mRNA /DB_XREF=gi:4500007 /UG=Hs.302050 Homo sapiens mRNA; cDNA DKFZp564E233 (from clone DKFZp564E233) AL049260 216519_s_at AK021923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021923.1 /DEF=Homo sapiens cDNA FLJ11861 fis, clone HEMBA1006885, highly similar to Homo sapiens gene for Proline synthetase associated. /FEA=mRNA /DB_XREF=gi:10433221 /UG=Hs.301959 proline synthetase co-transcribed (bacterial homolog) AK021923 proline synthetase co-transcribed homolog (bacterial) PROSC 11212 NM_007198 /// XM_005273395 1901605 // alpha-amino acid metabolic process // not recorded 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0030170 // pyridoxal phosphate binding // not recorded 216520_s_at AF072098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072098 /DEF=Homo sapiens HDCMB21P gene, complete cds /FEA=CDS /DB_XREF=gi:5725513 /UG=Hs.279860 tumor protein, translationally-controlled 1 AF072098 uncharacterized LOC101928826 /// tumor protein, translationally-controlled 1 LOC101928826 /// TPT1 7178 /// 101928826 NM_001286272 /// NM_001286273 /// NM_003295 /// XR_242670 /// XR_250536 /// XR_252641 0006816 // calcium ion transport // inferred by curator /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0009615 // response to virus // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000384 // negative regulation of ectoderm development // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005771 // multivesicular body // inferred from direct assay /// 0045298 // tubulin complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216521_s_at S72931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S72931 /DEF=Homo sapiens T-cell receptor alpha chain-c6.1A fusion protein (c6.1A-TCRC) gene, partial cds /FEA=CDS /DB_XREF=gi:639612 /UG=Hs.301927 c6.1A S72931 BRCA1/BRCA2-containing complex, subunit 3 BRCC3 79184 NM_001018055 /// NM_001242640 /// NM_024332 /// XM_005274749 /// XM_005274750 /// XM_005274751 /// XM_006724846 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070537 // histone H2A K63-linked deubiquitination // inferred from direct assay /// 0070537 // histone H2A K63-linked deubiquitination // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000152 // nuclear ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216522_at AL133267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133267 /DEF=Human DNA sequence from clone RP3-408B20 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a gene and two pseudogenes for novel 7 transmembrane receptors (olfactory family) and a gene for a novel protein similar to 60S acidic ribosomal protei... /FEA=CDS_1 /DB_XREF=gi:10185396 /UG=Hs.302086 Human DNA sequence from clone RP3-408B20 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a gene and two pseudogenes for novel 7 transmembrane receptors (olfactory family) and a gene for a novel protein similar to 60S acidic ribosomal protein P2 (RP AL133267 olfactory receptor, family 2, subfamily B, member 6 OR2B6 26212 NM_012367 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 216524_x_at AL049260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049260.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E233 (from clone DKFZp564E233). /FEA=mRNA /DB_XREF=gi:4500007 /UG=Hs.302050 Homo sapiens mRNA; cDNA DKFZp564E233 (from clone DKFZp564E233) AL049260 216525_x_at D38437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38437.1 /DEF=Homo sapiens hPMS5 mRNA, partial cds. /FEA=mRNA /GEN=hPMS5 /DB_XREF=gi:600592 /UG=Hs.278467 postmeiotic segregation increased 2-like 3 D38437 postmeiotic segregation increased 2 pseudogene 3 PMS2P3 5387 NM_001003686 /// NM_005395 /// NR_028059 0006298 // mismatch repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0032300 // mismatch repair complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 216526_x_at AK024836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024836.1 /DEF=Homo sapiens cDNA: FLJ21183 fis, clone CAS11634, highly similar to HSHLACW07 Homo sapiens mRNA for human leukocyte antigen C alpha chain. /FEA=mRNA /DB_XREF=gi:10437242 /UG=Hs.277477 major histocompatibility complex, class I, C AK024836 major histocompatibility complex, class I, C HLA-C 3107 NM_001243042 /// NM_002117 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002486 // antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from direct assay /// 0042612 // MHC class I protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0046977 // TAP binding // inferred from direct assay 216527_at AL049252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049252.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D193 (from clone DKFZp564D193). /FEA=mRNA /DB_XREF=gi:4499993 /UG=Hs.302048 Homo sapiens mRNA; cDNA DKFZp564D193 (from clone DKFZp564D193) AL049252 HLA complex group 18 (non-protein coding) HCG18 414777 NR_024052 /// NR_024053 /// NR_102326 /// NR_102327 216528_at AL049244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049244.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C163 (from clone DKFZp564C163). /FEA=mRNA /DB_XREF=gi:4499979 /UG=Hs.302046 Homo sapiens mRNA; cDNA DKFZp564C163 (from clone DKFZp564C163) AL049244 216529_at AL049244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049244.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C163 (from clone DKFZp564C163). /FEA=mRNA /DB_XREF=gi:4499979 /UG=Hs.302046 Homo sapiens mRNA; cDNA DKFZp564C163 (from clone DKFZp564C163) AL049244 216530_at AL137435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137435.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G0924 (from clone DKFZp761G0924). /FEA=mRNA /DB_XREF=gi:6807994 /UG=Hs.274577 Homo sapiens mRNA; cDNA DKFZp761G0924 (from clone DKFZp761G0924) AL137435 216531_at U73479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U73479 /DEF=Homo sapiens cosmid clone U138C3 from Xp22.1-22.2 /FEA=CDS /DB_XREF=gi:2565031 /UG=Hs.302065 Homo sapiens cosmid clone U138C3 from Xp22.1-22.2 U73479 membrane-bound transcription factor peptidase, site 2 /// YY2 transcription factor MBTPS2 /// YY2 51360 /// 404281 NM_015884 /// NM_206923 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216532_x_at AL138831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL138831 /DEF=Human DNA sequence from clone RP3-406P24 on chromosome 6 Contains a thioredoxin-like pseudogene, 2 CpG islands, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9863510 /UG=Hs.302081 Human DNA sequence from clone RP3-406P24 on chromosome 6 Contains a thioredoxin-like pseudogene, 2 CpG islands, ESTs, STSs and GSSs AL138831 RP3-406P24.1 216533_at AL122056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122056.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P088 (from clone DKFZp434P088). /FEA=mRNA /DB_XREF=gi:6093253 /UG=Hs.274557 Homo sapiens mRNA; cDNA DKFZp434P088 (from clone DKFZp434P088) AL122056 propionyl CoA carboxylase, alpha polypeptide PCCA 5095 NM_000282 /// NM_001127692 /// NM_001178004 /// XM_005254059 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0004658 // propionyl-CoA carboxylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216534_at AL110223 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110223.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M063 (from clone DKFZp434M063). /FEA=mRNA /DB_XREF=gi:5817158 /UG=Hs.274521 Homo sapiens mRNA; cDNA DKFZp434M063 (from clone DKFZp434M063) AL110223 216535_at AL050219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050219.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J1623 (from clone DKFZp586J1623). /FEA=mRNA /DB_XREF=gi:4884460 /UG=Hs.274514 Homo sapiens mRNA; cDNA DKFZp586J1623 (from clone DKFZp586J1623) AL050219 cell adhesion molecule 3 CADM3 57863 NM_001127173 /// NM_021189 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 216536_at AC006271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006271 /DEF=Homo sapiens chromosome 19, BAC 319430 (CIT-B-440L2) /FEA=CDS_1 /DB_XREF=gi:4092817 /UG=Hs.302064 olfactory receptor, family 7, subfamily E, member 19 pseudogene AC006271 olfactory receptor, family 7, subfamily E, member 19 pseudogene OR7E19P 26651 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement 216537_s_at AJ130713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ130713.1 /DEF=Homo sapiens mRNA for QA79 membrane protein, splice product airm-1. /FEA=mRNA /GEN=airm /PROD=QA79 membrane protein, splice product airm-1 /DB_XREF=gi:5541875 /UG=Hs.274470 sialic acid binding Ig-like lectin 7 AJ130713 sialic acid binding Ig-like lectin 7 SIGLEC7 27036 NM_001277201 /// NM_014385 /// NM_016543 /// NR_102350 /// XM_006723140 0007155 // cell adhesion // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // traceable author statement 216538_at AL049351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049351.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566C093 (from clone DKFZp566C093). /FEA=mRNA /DB_XREF=gi:4500138 /UG=Hs.302058 Homo sapiens mRNA; cDNA DKFZp566C093 (from clone DKFZp566C093) AL049351 216539_at AB050195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB050195.1 /DEF=Homo sapiens mRNA, partial cds, clone:H2-5, MJD homolog. /FEA=mRNA /DB_XREF=gi:11559487 /UG=Hs.302079 Homo sapiens mRNA, partial cds, clone:H2-5, MJD homolog AB050195 ataxin 3-like ATXN3L 92552 NM_001135995 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216540_at X61072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61072.1 /DEF=Human mRNA for T cell receptor, clone IGRA17. /FEA=mRNA /PROD=T cell receptor /DB_XREF=gi:33511 /UG=Hs.272500 Human mRNA for T cell receptor, clone IGRA17 X61072 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216541_x_at AJ275397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275397 /DEF=Homo sapiens partial IGVH1 gene for immunoglobulin heavy chain V region, case 1, cell Mo V 94 /FEA=CDS /DB_XREF=gi:7573056 /UG=Hs.272359 Homo sapiens partial IGVH1 gene for immunoglobulin heavy chain V region, case 1, cell Mo V 94 AJ275397 immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHG1 /// IGHM 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216542_x_at AJ275355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275355 /DEF=Homo sapiens partial IGVH3 V3-20 gene for immunoglobulin heavy chain V region, case 1, clone 2 /FEA=CDS /DB_XREF=gi:7572968 /UG=Hs.272355 Homo sapiens partial IGVH3 V3-20 gene for immunoglobulin heavy chain V region, case 1, clone 2 AJ275355 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHA1 /// IGHG1 /// IGHM 3493 /// 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216543_at AB050195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB050195.1 /DEF=Homo sapiens mRNA, partial cds, clone:H2-5, MJD homolog. /FEA=mRNA /DB_XREF=gi:11559487 /UG=Hs.302079 Homo sapiens mRNA, partial cds, clone:H2-5, MJD homolog AB050195 unknown transcript GS1-600G8.3 100093698 NR_046087 216544_at AC007320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007320 /DEF=Homo sapiens BAC clone RP11-477B5 from Y /FEA=CDS_1 /DB_XREF=gi:5732146 /UG=Hs.302072 Homo sapiens BAC clone RP11-477B5 from Y AC007320 RNA binding motif protein, Y-linked, family 1, member A1 pseudogene /// RNA binding motif protein, Y-linked, family 2, member F pseudogene LOC100652931 /// RBMY2FP 159162 /// 100652931 NR_002193 /// NR_104151 216545_at AL049710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049710 /DEF=Human DNA sequence from clone 633H17 on chromosome 1p31.2-32.2. Contains a pseudogene similar to part of MTCO1 (Cytochrome C oxidase 1), MTCO2 (cytochrome c oxidase II), MTATP8 (ATP synthase 8) and GOT2 glutamic-oxaloacetic transaminase 2, mitocho... /FEA=CDS_2 /DB_XREF=gi:5650682 /UG=Hs.272293 Human DNA sequence from clone 633H17 on chromosome 1p31.2-32.2. Contains a pseudogene similar to part of MTCO1 (Cytochrome C oxidase 1), MTCO2 (cytochrome c oxidase II), MTATP8 (ATP synthase 8) and GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial ( AL049710 glutamic-oxaloacetic transaminase 2 pseudogene 1 /// GOT2P1 /// GOT2P1 216546_s_at AJ251847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ251847 /DEF=Homo sapiens partial CHI3L1 gene for cartilage glycoprotein-39, exons 10-13 /FEA=mRNA_1 /DB_XREF=gi:7160990 /UG=Hs.272335 Homo sapiens partial CHI3L1 gene for cartilage glycoprotein-39, exons 10-13 AJ251847 chitinase 3-like 1 (cartilage glycoprotein-39) CHI3L1 1116 NM_001276 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from expression pattern /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0051216 // cartilage development // non-traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from expression pattern /// 0070741 // response to interleukin-6 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072606 // interleukin-8 secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008061 // chitin binding // inferred from direct assay 216547_at AL353681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353681 /DEF=Human DNA sequence from clone RP1-158P9 on chromosome 1. Contains a putative novel gene, a laminin receptor 1 (67kD, ribosomal protein SA) (LAMR1) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9801361 /UG=Hs.302094 Human DNA sequence from clone RP1-158P9 on chromosome 1. Contains a putative novel gene, a laminin receptor 1 (67kD, ribosomal protein SA) (LAMR1) pseudogene, ESTs, STSs and GSSs AL353681 RP4-710M16.1 216548_x_at AL049709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049709 /DEF=Human DNA sequence from clone RP1-18C9 on chromosome 20 Contains part of a novel gene similar to acetyl-coenzyme A synthetase, a novel gene (locus D20S101) similar to Gamma-glutamyltranspeptidase (contains CCA trinucleotide repeat), a gene similar... /FEA=CDS_1 /DB_XREF=gi:10198635 /UG=Hs.272268 Human DNA sequence from clone RP1-18C9 on chromosome 20 Contains part of a novel gene similar to acetyl-coenzyme A synthetase, a novel gene (locus D20S101) similar to Gamma-glutamyltranspeptidase (contains CCA trinucleotide repeat), a gene similar to HMG2 AL049709 high mobility group box 3 pseudogene 1 HMGB3P1 128872 NR_002165 216549_s_at AL096712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096712 /DEF=Human DNA sequence from clone RP4-744I24 on chromosome 6p12.1-21.2 Contains a novel gene (KIAA0646 (new zinc finger protein)), part of a novel gene (similar to a novel human gene mapping to chomosome 22q13.3 similar to yeast ORF YOR070C, putative... /FEA=CDS_2 /DB_XREF=gi:6425593 /UG=Hs.26898 hypothetical protein FLJ20337 AL096712 TBC1 domain family, member 22B TBC1D22B 55633 NM_017772 /// XR_241906 /// XR_427833 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 216550_x_at X80821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X80821.1 /DEF=H.sapiens mRNA for ribosomal protein L18a homologue. /FEA=mRNA /PROD=ribosomal protein L18a homologue /DB_XREF=gi:527579 /UG=Hs.302177 H.sapiens mRNA for ribosomal protein L18a homologue X80821 ankyrin repeat domain 12 ANKRD12 23253 NM_001083625 /// NM_001204056 /// NM_015208 /// XM_005258092 /// XM_005258093 /// XM_005258094 /// XM_005258095 /// XM_005258096 /// XM_006722317 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 216551_x_at AL110247 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110247.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N101 (from clone DKFZp434N101); partial cds. /FEA=mRNA /GEN=DKFZp434N101 /PROD=hypothetical protein /DB_XREF=gi:5817196 /UG=Hs.268177 phospholipase C, gamma 1 (formerly subtype 148) AL110247 phospholipase C, gamma 1 PLCG1 5335 NM_002660 /// NM_182811 /// XM_005260438 /// XR_244143 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216552_x_at AF135564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF135564.1 /DEF=Homo sapiens p50 killer cell activating receptor KAR-K1d mRNA, alternatively spliced, partial cds. /FEA=mRNA /PROD=p50 killer cell activating receptor KAR-K1d /DB_XREF=gi:5730901 /UG=Hs.258612 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 AF135564 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 KIR2DS4 3809 NM_001281971 /// NM_001281972 /// NM_012314 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216553_x_at AL121890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121890 /DEF=Human DNA sequence from clone RP5-1116H23 on chromosome 20 Contains a novel gene, a 40S ribosomal protein S21 pseudogene, 2 CpG islands, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:10862829 /UG=Hs.302106 Human DNA sequence from clone RP5-1116H23 on chromosome 20 Contains a novel gene, a 40S ribosomal protein S21 pseudogene, 2 CpG islands, ESTs, STSs and GSSs AL121890 uncharacterized LOC102724905 LOC102724905 102724905 XM_006723673 216554_s_at U88968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U88968.1 /DEF=Human alpha enolase like 1 (ENO1L1) mRNA, partial cds. /FEA=mRNA /GEN=ENO1L1 /PROD=alpha enolase like 1 /DB_XREF=gi:3282242 /UG=Hs.254105 enolase 1, (alpha) U88968 enolase 1, (alpha) ENO1 2023 NM_001201483 /// NM_001428 /// XM_006710433 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216555_at AK026712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026712.1 /DEF=Homo sapiens cDNA: FLJ23059 fis, clone LNG03912. /FEA=mRNA /DB_XREF=gi:10439629 /UG=Hs.252259 ribosomal protein S3 AK026712 proline rich 14-like PRR14L 253143 NM_173566 /// XM_005261480 /// XM_006724219 /// XM_006724220 /// XM_006724221 216556_x_at AL135926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL135926 /DEF=Human DNA sequence from clone RP11-375F2 on chromosome 1 Contains a pseudogene similar to UBL1 (ubiquitin-like 1 (sentrin)), a pseudogene similar to ribosomal protein L29, ESTs, STSs and GSSs /FEA=CDS_1 /DB_XREF=gi:9801286 /UG=Hs.302113 Human DNA sequence from clone RP11-375F2 on chromosome 1 Contains a pseudogene similar to UBL1 (ubiquitin-like 1 (sentrin)), a pseudogene similar to ribosomal protein L29, ESTs, STSs and GSSs AL135926 SUMO1 pseudogene 2 /// SUMO1P2 /// SUMO1P2 216557_x_at U92706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U92706 /DEF=Human rearranged immunoglobulin heavy chain (A1VH3) gene, partial cds /FEA=CDS /DB_XREF=gi:2155271 /UG=Hs.249245 Homo sapiens mRNA for single-chain antibody, complete cds U92706 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHD /// IGHG1 /// IGHG3 /// IGHM /// IGHV4-31 3493 /// 3495 /// 3500 /// 3502 /// 3507 /// 28396 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216558_x_at AF044595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF044595 /DEF=Homo sapiens lymphocyte-predominant Hodgkins disease case 7 immunoglobulin heavy chain gene, variable region, partial cds /FEA=CDS /DB_XREF=gi:2852426 /UG=Hs.248078 Homo sapiens lymphocyte-predominant Hodgkins disease case 7 immunoglobulin heavy chain gene, variable region, partial cds AF044595 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHD /// IGHG1 /// IGHG2 /// IGHG3 /// IGHM /// IGHV4-31 3493 /// 3495 /// 3500 /// 3501 /// 3502 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216559_x_at AL050348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050348 /DEF=Human DNA sequence from clone RP3-447F3 on chromosome 20. Contains ESTs, STSs, GSSs and CpG islands. Contains the 3 part of a gene for a novel protein similar to heterogenous nuclear ribonucleoprotein A1 (helix destabilizing protein, single-stra... /FEA=mRNA_1 /DB_XREF=gi:9408738 /UG=Hs.302108 Human DNA sequence from clone RP3-447F3 on chromosome 20. Contains ESTs, STSs, GSSs and CpG islands. Contains the 3 part of a gene for a novel protein similar to heterogenous nuclear ribonucleoprotein A1 (helix destabilizing protein, single-strand-bindi AL050348 heterogeneous nuclear ribonucleoprotein A1 pseudogene 3 /// HNRNPA1P3 /// HNRNPA1P3 216560_x_at D87021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D87021 /DEF=Homo sapiens immunoglobulin lambda gene locus DNA, clone:84E4 /FEA=CDS /DB_XREF=gi:2114286 /UG=Hs.249208 immunoglobulin lambda variable 3-10 D87021 immunoglobulin lambda constant 1 (Mcg marker) /// immunoglobulin lambda variable 3-10 /// IGLC1 /// IGLV3-10 /// IGLV3-10 3537 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216561_x_at AF032454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF032454 /DEF=Homo sapiens SOX-29 protein (SOX29) gene, partial cds /FEA=CDS /DB_XREF=gi:3982590 /UG=Hs.248220 SOX29 AF032454 SRY (sex determining region Y)-box 5 pseudogene /// SOX5P /// SOX5P 216562_at AL121777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121777 /DEF=Human DNA sequence from clone RP5-1057D4 on chromosome 20 Contains a Spermidine synthase (SPDSY) pseudogene, a CpG island, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:10862842 /UG=Hs.302107 Human DNA sequence from clone RP5-1057D4 on chromosome 20 Contains a Spermidine synthase (SPDSY) pseudogene, a CpG island, ESTs, STSs and GSSs AL121777 spermidine synthase pseudogene 1 /// SRMP1 /// SRMP1 216563_at X80821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X80821.1 /DEF=H.sapiens mRNA for ribosomal protein L18a homologue. /FEA=mRNA /PROD=ribosomal protein L18a homologue /DB_XREF=gi:527579 /UG=Hs.302177 H.sapiens mRNA for ribosomal protein L18a homologue X80821 ankyrin repeat domain 12 ANKRD12 23253 NM_001083625 /// NM_001204056 /// NM_015208 /// XM_005258092 /// XM_005258093 /// XM_005258094 /// XM_005258095 /// XM_005258096 /// XM_006722317 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation 216564_at AC003989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003989 /DEF=Human BAC clone CTB-7J15 from 7q31 /FEA=CDS /DB_XREF=gi:2772538 /UG=Hs.248069 Human BAC clone CTB-7J15 from 7q31 AC003989 AC003989.4 216565_x_at AL121994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121994 /DEF=Human DNA sequence from clone RP4-781L3 on chromosome 1p34.3-36.11 Contains a pseudogene similar to IFITM3 (interferon inducedntransmembrane protein 3 (1-8U)), STSs and GSSs /FEA=CDS /DB_XREF=gi:8648917 /UG=Hs.302117 Human DNA sequence from clone RP4-781L3 on chromosome 1p34.3-36.11 Contains a pseudogene similar to IFITM3 (interferon inducedntransmembrane protein 3 (1-8U)), STSs and GSSs AL121994 RP4-781L3.1 216566_at D84140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D84140.1 /DEF=Human immunoglobulin (mAb56) light chain V region mRNA, partial sequence. /FEA=mRNA /PROD=immunoglobulin light chain V-J region /DB_XREF=gi:1255610 /UG=Hs.248043 Human immunoglobulin (mAb56) light chain V region mRNA, partial sequence D84140 216567_at L41657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L41657 /DEF=Homo sapiens synthetic myelin basic protein 21.5 kDa isoform gene, complete cds /FEA=CDS /DB_XREF=gi:1162921 /UG=Hs.248022 Homo sapiens synthetic myelin basic protein 21.5 kDa isoform gene, complete cds L41657 216568_x_at Z83821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z83821 /DEF=Human DNA sequence from PAC 296K21 on chromosome X contains cytokeratin exon, delta-aminolevulinate synthase (erythroid); 5-aminolevulinic acid synthase.(EC 2.3.1.37). 6-phosphofructo-2-kinasefructose-2,6-bisphosphatase (EC 2.7.1.105, EC 3.1.3.46... /FEA=CDS_2 /DB_XREF=gi:1869771 /UG=Hs.247994 Human DNA sequence from PAC 296K21 on chromosome X contains cytokeratin exon, delta-aminolevulinate synthase (erythroid); 5-aminolevulinic acid synthase.(EC 2.3.1.37). 6-phosphofructo-2-kinasefructose-2,6-bisphosphatase (EC 2.7.1.105, EC 3.1.3.46), ESTs Z83821 216569_at U72237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U72237 /DEF=Homo sapiens fatty acid-binding protein (FABP3-ps) pseudogene, complete cds /FEA=CDS /DB_XREF=gi:1778305 /UG=Hs.247985 fatty acid binding protein 3, pseudogene 2 U72237 fatty acid binding protein 3, pseudogene 2 /// FABP3P2 /// FABP3P2 216570_x_at AL096829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096829 /DEF=Human DNA sequence from clone RP4-595K12 on chromosome 1p31.2-31.3 Contains a pseudogene similar to 60S RPL29 (ribosomal protein L29 (cell surface heparin binding protein HIP)), a chromosome 1 specific mRNA (KIAA0499), a novel mRNA (KIAA0433), EST... /FEA=CDS /DB_XREF=gi:6634461 /UG=Hs.302120 Human DNA sequence from clone RP4-595K12 on chromosome 1p31.2-31.3 Contains a pseudogene similar to 60S RPL29 (ribosomal protein L29 (cell surface heparin binding protein HIP)), a chromosome 1 specific mRNA (KIAA0499), a novel mRNA (KIAA0433), ESTs, STSs, AL096829 RP4-595K12.1 216571_at M81780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M81780 /DEF=Homo sapiens acid sphingomyelinase (SMPD1) gene, complete cds, ORFs 1-3, complete cdss /FEA=CDS_1 /DB_XREF=gi:972768 /UG=Hs.247961 Homo sapiens acid sphingomyelinase (SMPD1) gene, complete cds, ORFs 1-3, complete cdss M81780 216572_at AF315075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF315075 /DEF=Homo sapiens forkhead family transcription factor FOXL1 (FOXL1) gene, complete cds /FEA=CDS /DB_XREF=gi:11762067 /UG=Hs.302164 forkhead box L1 AF315075 forkhead box L1 FOXL1 2300 NM_005250 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007389 // pattern specification process // not recorded /// 0007420 // brain development // not recorded /// 0007495 // visceral mesoderm-endoderm interaction involved in midgut development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from mutant phenotype /// 0009790 // embryo development // /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0009888 // tissue development // not recorded /// 0030111 // regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030166 // proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // not recorded /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0008301 // DNA binding, bending // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay 216573_at X84340 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X84340.1 /DEF=H.sapiens mRNA for Ig light chain, variable region (ID:CLL001VL). /FEA=mRNA /GEN=Ig VL gene /PROD=immunoglobulin light chain variable region /DB_XREF=gi:791011 /UG=Hs.247950 H.sapiens mRNA for Ig light chain, variable region (ID:CLL001VL) X84340 immunoglobulin lambda variable 1-44 IGLV1-44 28823 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216574_s_at J04742 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J04742 /DEF=Human autonomous replicating sequence H1 (ARSH1) /FEA=CDS /DB_XREF=gi:179028 /UG=Hs.247945 Human autonomous replicating sequence H1 (ARSH1) J04742 ribulose-5-phosphate-3-epimerase /// ribulose-5-phosphate-3-epimerase-like 1 RPE /// RPEL1 6120 /// 729020 NM_001143909 /// NM_001278282 /// NM_001278283 /// NM_001278285 /// NM_001278286 /// NM_001278288 /// NM_001278289 /// NM_006916 /// NM_199229 /// XM_006712677 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004750 // ribulose-phosphate 3-epimerase activity // not recorded /// 0004750 // ribulose-phosphate 3-epimerase activity // inferred from direct assay /// 0004750 // ribulose-phosphate 3-epimerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 216575_at AL035604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035604 /DEF=Human DNA sequence from clone 38C16 on chromosome 6q22.33-24.1. Contains GAPD (glyceraldehyde 3-phosphate dehydrogenease, GAPDH) and HMG1 (high mobility group protein 1) pseudogenes, ESTs, STSs and GSSs /FEA=CDS_2 /DB_XREF=gi:5002622 /UG=Hs.247895 Human DNA sequence from clone 38C16 on chromosome 6q22.33-24.1. Contains GAPD (glyceraldehyde 3-phosphate dehydrogenease, GAPDH) and HMG1 (high mobility group protein 1) pseudogenes, ESTs, STSs and GSSs AL035604 high mobility group box 1 pseudogene 17 /// HMGB1P17 /// HMGB1P17 216576_x_at AF103529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103529.1 /DEF=Homo sapiens isolate donor N clone N88K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4378387 /UG=Hs.247910 Homo sapiens isolate donor N clone N88K immunoglobulin kappa light chain variable region mRNA, partial cds AF103529 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216577_at AL049690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049690 /DEF=Human DNA sequence from clone 1060K6 on chromosome 20p12.1-13 Contains a pseudogene similar to 40S ribosomal protein S11, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9795212 /UG=Hs.247904 Human DNA sequence from clone 1060K6 on chromosome 20p12.1-13 Contains a pseudogene similar to 40S ribosomal protein S11, ESTs, STSs and GSSs AL049690 ribosomal protein S11 pseudogene 1 /// RPS11P1 /// RPS11P1 216578_at AF009660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009660 /DEF=Homo sapiens T cell receptor beta locus, TCRBV7S3A2 to TCRBV12S2 region /FEA=CDS_2 /DB_XREF=gi:2275560 /UG=Hs.303157 T cell receptor beta locus AF009660 T cell receptor beta variable 5-2 (pseudogene) /// TRBV5-2 /// TRBV5-2 216579_at AL121988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121988 /DEF=Human DNA sequence from clone RP1-34M23 on chromosome 1p34.3-36.11 Contains 4 gap junction protein (connexin) genes (GJA4, GJB3, GJB4, GJB5), an EST, STSs, GSSs and a CpG Island /FEA=mRNA_2 /DB_XREF=gi:7330683 /UG=Hs.302417 Human DNA sequence from clone RP1-34M23 on chromosome 1p34.3-36.11 Contains 4 gap junction protein (connexin) genes (GJA4, GJB3, GJB4, GJB5), an EST, STSs, GSSs and a CpG Island AL121988 gap junction protein, beta 4, 30.3kDa GJB4 127534 NM_153212 0007154 // cell communication // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0042048 // olfactory behavior // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // non-traceable author statement 216580_at AL049545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049545 /DEF=Human DNA sequence from clone 263J7 on chromosome 6q14.3-15. Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, a RAB1 (RAB1, member RAS oncogene family) pseudogene, ESTs, an STS and GSSs /FEA=CDS_1 /DB_XREF=gi:5002650 /UG=Hs.247877 Human DNA sequence from clone 263J7 on chromosome 6q14.3-15. Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, a RAB1 (RAB1, member RAS oncogene family) pseudogene, ESTs, an STS and GSSs AL049545 /// ribosomal protein L7 pseudogene 27 RP1-263J7.1 /// RPL7P27 216581_at AL022068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022068 /DEF=Human DNA sequence from clone 167F1 on chromosome 6p22.1-22.3. Contains a KRT18 (Keratin, type 1 Cytoskeletal 18 (CYK18, Cytokeratin 18, CK18)) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:4467305 /UG=Hs.247858 Human DNA sequence from clone 167F1 on chromosome 6p22.1-22.3. Contains a KRT18 (Keratin, type 1 Cytoskeletal 18 (CYK18, Cytokeratin 18, CK18)) pseudogene, ESTs, STSs and GSSs AL022068 keratin 18 pseudogene 38 /// KRT18P38 /// KRT18P38 216582_at AL021808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021808 /DEF=Human DNA sequence from clone XXbac-24o18 on chromosome 6p21.31-22.2 Contains zinc finger protein pseudogene, VNO-type olfactory receptor pseudogene, the gene for PRSS16 (protease, serine, 16 (thymus)), the gene for nuclear envelope pore membrane ... /FEA=mRNA_3 /DB_XREF=gi:3395513 /UG=Hs.247805 Human DNA sequence from clone 24o18 on chromosome 6p21.31-22.2 Contains zinc finger protein pseudogene, VNO-type olfactory receptor pseudogene, nuclear envelope pore membrane protein, EST, STS, GSS AL021808 POM121 transmembrane nucleoporin-like 2 POM121L2 94026 NM_033482 216583_x_at AC004079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004079 /DEF=Homo sapiens PAC clone RP1-167F23 from 7p15 /FEA=CDS_2 /DB_XREF=gi:2822174 /UG=Hs.302184 Homo sapiens PAC clone RP1-167F23 from 7p15 AC004079 NHP2 ribonucleoprotein pseudogene 2 /// NHP2P2 /// NHP2P2 216584_at AL031291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031291 /DEF=Human DNA sequence from clone 796F18 on chromosome 1p36.11-36.33 Contains a pseudogene similar to MMS2, ESTs and GSSs /FEA=CDS /DB_XREF=gi:4481883 /UG=Hs.247848 Human DNA sequence from clone 796F18 on chromosome 1p36.11-36.33 Contains a pseudogene similar to MMS2, ESTs and GSSs AL031291 ubiquitin-conjugating enzyme E2 variant 2 pseudgene 3 /// UBE2V2P3 /// UBE2V2P3 216585_at AL031777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031777 /DEF=Human DNA sequence from clone 34B20 on chromosome 6p21.31-22.2. Contains seventeen Histone (pseudo)genes and a 40S Ribosomal protein S10 pseudogene. Contains ESTs, STSs and GSSs /FEA=CDS_3 /DB_XREF=gi:10198609 /UG=Hs.247812 Homo sapiens, clone MGC:12935, mRNA, complete cds AL031777 histone cluster 1, H2a, pseudogene 4 /// HIST1H2APS4 /// HIST1H2APS4 216586_at X92986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X92986 /DEF=H.sapiens UNG2 pseudogene /FEA=CDS /DB_XREF=gi:1067135 /UG=Hs.247799 uracil-DNA glycosylase pseudogene 2 X92986 216587_s_at AL121749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121749 /DEF=Human DNA sequence from clone RP11-425A6 on chromosome 10 Contains the FZD8 (frizzled (Drosophila) homolog 8) gene, part of a gene similar to connexin, ESTs, STSs, GSSs and CpG Islands /FEA=CDS_2 /DB_XREF=gi:7530251 /UG=Hs.302634 Human DNA sequence from clone RP11-425A6 on chromosome 10 Contains the FZD8 (frizzled (Drosophila) homolog 8) gene, part of a gene similar to connexin, ESTs, STSs, GSSs and CpG Islands AL121749 frizzled class receptor 8 /// microRNA 4683 FZD8 /// MIR4683 8325 /// 100616500 NM_031866 /// NR_039831 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // not recorded /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0042995 // cell projection // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0042813 // Wnt-activated receptor activity // traceable author statement 216588_at AL031577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031577 /DEF=Human DNA sequence from clone 391O22 on chromosome 6p21.2-21.31. Contains pseudogenes similar to ribosomal proteins L44 and L30, a pseudogene similar to interferon-inducible protein 1-8U, ESTs, GSSs /FEA=CDS /DB_XREF=gi:3786166 /UG=Hs.247779 Human DNA sequence from clone 391O22 on chromosome 6p21.2-21.31. Contains pseudogenes similar to ribosomal proteins L44 and L30, a pseudogene similar to interferon-inducible protein 1-8U, ESTs, GSSs AL031577 /// ribosomal protein L7 pseudogene 25 RP3-391O22.2 /// RPL7P25 216589_at AL031276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031276 /DEF=Human DNA sequence from clone 1118D24 on chromosome 1p36.11-36.33. Contains part of a novel gene similar to worm genes T08G11.1 and C25H3.9, part of a 60S Ribosomal Protein L10 LIKE (pseudo)gene and two 3 exons of the TNFR2 gene for Tumor Necrosi... /FEA=CDS_3 /DB_XREF=gi:3947780 /UG=Hs.247773 Human DNA sequence from clone 1118D24 on chromosome 1p36.11-36.33. Contains part of a novel gene similar to worm genes T08G11.1 and C25H3.9, part of a 60S Ribosomal Protein L10 LIKE (pseudo)gene and two 3 exons of the TNFR2 gene for Tumor Necrosis Factor AL031276 RP5-1118D24.2 216590_at AC004862 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004862 /DEF=Homo sapiens PAC clone RP4-697H17 from 7q11.23-q21.1 /FEA=CDS /DB_XREF=gi:3900856 /UG=Hs.247768 Homo sapiens PAC clone RP4-697H17 from 7q11.23-q21.1 AC004862 guanine nucleotide binding protein, alpha transducing 3 GNAT3 346562 NM_001102386 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009584 // detection of visible light // /// 0030168 // platelet activation // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // not recorded /// 0050917 // sensory perception of umami taste // not recorded 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0001750 // photoreceptor outer segment // not recorded /// 0001917 // photoreceptor inner segment // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005930 // axoneme // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0008020 // G-protein coupled photoreceptor activity // /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 216591_s_at AF080579 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF080579 /DEF=Homo sapiens integral membrane protein subunit of complex II (CII-3) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3406740 /UG=Hs.247725 Homo sapiens integral membrane protein subunit of complex II (CII-3) pseudogene, complete sequence AF080579 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa SDHC 6391 NM_001035511 /// NM_001035512 /// NM_001035513 /// NM_001278172 /// NM_003001 /// NR_103459 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0045273 // respiratory chain complex II // traceable author statement /// 0045281 // succinate dehydrogenase complex // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 216592_at AL022152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022152 /DEF=Homo sapiens DNA sequence from PAC 232G24 on chromosome Xq27.1-q27.3. Contains two exons similar to MAGE gene family, EST, CA repeat, STS /FEA=CDS /DB_XREF=gi:3150086 /UG=Hs.247705 Homo sapiens DNA sequence from PAC 232G24 on chromosome Xq27.1-q27.3. Contains two exons similar to MAGE gene family, EST, CA repeat, STS AL022152 melanoma antigen family C, 3 MAGEC3 139081 NM_138702 /// NM_177456 /// XM_005262366 216593_s_at AB000359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB000359 /DEF=Homo sapiens PIGCP1 pseudogene /FEA=CDS /DB_XREF=gi:2547040 /UG=Hs.306173 phosphatidylinositol glycan, class C, pseudogene 1 AB000359 phosphatidylinositol glycan anchor biosynthesis, class C PIGC 5279 NM_002642 /// NM_153747 /// XM_006711383 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation 216594_x_at S68290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S68290.1 /DEF=chlordecone reductase homolog {clone HAKRc} human, liver, mRNA, 1158 nt. /FEA=mRNA /GEN=chlordecone reductase homolog /DB_XREF=gi:544763 /UG=Hs.306098 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) S68290 aldo-keto reductase family 1, member C1 AKR1C1 1645 NM_001353 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation 216595_at AL049983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049983.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D042 (from clone DKFZp564D042). /FEA=mRNA /DB_XREF=gi:4884234 /UG=Hs.240136 Homo sapiens mRNA; cDNA DKFZp564D042 (from clone DKFZp564D042) AL049983 family with sequence similarity 186, member A FAM186A 121006 NM_001145475 /// XM_006719231 216596_at AL117445 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117445.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L187 (from clone DKFZp434L187); partial cds. /FEA=mRNA /GEN=DKFZp434L187 /PROD=hypothetical protein /DB_XREF=gi:5911891 /UG=Hs.241424 DKFZP434L187 protein AL117445 uncharacterized LOC26082 DKFZP434L187 26082 NR_026771 216597_at U66059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U66059 /DEF=Human germline T-cell receptor beta chain Dopamine-beta-hydroxylase-like, TRY1, TRY2, TRY3, TCRBV27S1P, TCRBV22S1A2N1T, TCRBV9S1A1T, TCRBV7S1A1N2T, TCRBV5S1A1T, TCRBV13S3, TCRBV6S7P, TCRBV7S3A2T, TCRBV13S2A1T, TCRBV9S2A2PT, TCRBV7S2A1N4T, TCRBV13S... /FEA=CDS_3 /DB_XREF=gi:1552494 /UG=Hs.303157 T cell receptor beta locus U66059 PRSS3P3 216598_s_at S69738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S69738.1 /DEF=MCP-1=monocyte chemotactic protein human, aortic endothelial cells, mRNA, 661 nt. /FEA=mRNA /GEN=MCP-1 /PROD=MCP-1 /DB_XREF=gi:545464 /UG=Hs.303649 small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) S69738 chemokine (C-C motif) ligand 2 CCL2 6347 NM_002982 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001525 // angiogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0009408 // response to heat // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from expression pattern /// 0009887 // organ morphogenesis // traceable author statement /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010574 // regulation of vascular endothelial growth factor production // inferred from electronic annotation /// 0010759 // positive regulation of macrophage chemotaxis // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019725 // cellular homeostasis // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033552 // response to vitamin B3 // inferred from electronic annotation /// 0034351 // negative regulation of glial cell apoptotic process // inferred from direct assay /// 0035684 // helper T cell extravasation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043615 // astrocyte cell migration // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071346 // cellular response to interferon-gamma // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0090265 // positive regulation of immune complex clearance by monocytes and macrophages // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 2000427 // positive regulation of apoptotic cell clearance // inferred from sequence or structural similarity /// 2000502 // negative regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0031727 // CCR2 chemokine receptor binding // inferred from sequence or structural similarity /// 0031727 // CCR2 chemokine receptor binding // traceable author statement 216599_x_at AJ271205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ271205.1 /DEF=Homo sapiens mRNA for putative organic anion transporter (OAT1-4 gene). /FEA=CDS /GEN=OAT1-4 /PROD=putative organic anion transporter /DB_XREF=gi:9367207 /UG=Hs.23965 solute carrier family 22 (organic anion transporter), member 6 AJ271205 solute carrier family 22 (organic anion transporter), member 6 SLC22A6 9356 NM_004790 /// NM_153276 /// NM_153277 /// NM_153278 /// NM_153279 0006820 // anion transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from direct assay /// 0015711 // organic anion transport // inferred from mutant phenotype /// 0015742 // alpha-ketoglutarate transport // inferred from direct assay /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // inferred from direct assay /// 0043252 // sodium-independent organic anion transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0097254 // renal tubular secretion // inferred from mutant phenotype /// 0097254 // renal tubular secretion // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005452 // inorganic anion exchanger activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0008514 // organic anion transmembrane transporter activity // inferred from mutant phenotype /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 216600_x_at AK026411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026411.1 /DEF=Homo sapiens cDNA: FLJ22758 fis, clone KAIA0811, highly similar to HUMALDB Human aldolase B mRNA. /FEA=mRNA /DB_XREF=gi:10439268 /UG=Hs.234234 aldolase B, fructose-bisphosphate AK026411 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 216601_at AF047485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF047485.1 /DEF=Homo sapiens amine oxidase pseudogene mRNA, splice variant HLAO1. /FEA=mRNA /DB_XREF=gi:3851493 /UG=Hs.306279 Homo sapiens amine oxidase pseudogene mRNA, splice variant HLAO1 AF047485 amine oxidase, copper containing 4, pseudogene AOC4P 90586 NR_002773 216602_s_at AD000092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AD000092 /DEF=Homo sapiens DNA from chromosome 19p13.2 cosmids R31240, R30272 and R28549 containing the EKLF, GCDH, CRTC, and RAD23A genes, genomic sequence /FEA=CDS_6 /DB_XREF=gi:1905905 /UG=Hs.23111 phenylalanine-tRNA synthetase-like AD000092 phenylalanyl-tRNA synthetase, alpha subunit FARSA 2193 NM_004461 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216603_at AL365343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL365343.2 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 32539. /FEA=mRNA /DB_XREF=gi:9187598 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 AL365343 solute carrier family 7 (amino acid transporter light chain, L system), member 8 SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 216604_s_at AL365343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL365343.2 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 32539. /FEA=mRNA /DB_XREF=gi:9187598 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 AL365343 solute carrier family 7 (amino acid transporter light chain, L system), member 8 SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 216605_s_at AC005626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005626 /DEF=Homo sapiens chromosome 19, cosmid R29124 /FEA=CDS /DB_XREF=gi:3549151 /UG=Hs.306268 Homo sapiens chromosome 19, cosmid R29124 AC005626 carcinoembryonic antigen-related cell adhesion molecule 21 CEACAM21 90273 NM_001098506 /// NM_001288773 /// NM_001290113 /// NM_033543 /// NR_110107 /// XM_005278396 /// XM_005278397 /// XM_006725394 /// XM_006725395 /// XM_006725396 /// XR_424988 /// XR_430247 /// XR_430808 /// XR_433578 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 216606_x_at AL050332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050332 /DEF=Human DNA sequence from clone RP4-570F3 on chromosome 6 Contains a gene similar to Rattus norvegicus synaptic ras GTPase-activating protein p135, the CICK0721Q.5 (polypeptide from patented cDNA Em:E06811) gene, the PHF1 (PHD finger protein 1) gen... /FEA=mRNA_1 /DB_XREF=gi:6010176 /UG=Hs.306238 acyl-protein AL050332 lysophospholipase II LYPLA2 11313 NM_007260 /// XM_005245728 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 216607_s_at U40053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U40053 /DEF=Human lanosterol 14-alpha demethylase (CYP51P2) processed pseudogene, complete cds /FEA=CDS /DB_XREF=gi:1184068 /UG=Hs.226213 cytochrome P450, 51 (lanosterol 14-alpha-demethylase) U40053 cytochrome P450, family 51, subfamily A, polypeptide 1 /// leucine-rich repeats and death domain containing 1 CYP51A1 /// LRRD1 1595 /// 401387 NM_000786 /// NM_001045475 /// NM_001146152 /// NM_001161528 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033488 // cholesterol biosynthetic process via 24,25-dihydrolanosterol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070988 // demethylation // inferred from direct assay /// 0070988 // demethylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008398 // sterol 14-demethylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216608_at AL080191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080191.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A062 (from clone DKFZp434A062); partial cds. /FEA=mRNA /GEN=DKFZp434A062 /PROD=hypothetical protein /DB_XREF=gi:5262671 /UG=Hs.226001 DKFZP434A062 protein AL080191 uncharacterized LOC26102 DKFZP434A062 26102 NR_026964 216609_at AF065241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF065241.1 /DEF=Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds. /FEA=mRNA /GEN=TXN delta 3 /PROD=thioredoxin delta 3 /DB_XREF=gi:3153858 /UG=Hs.306243 Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds AF065241 thioredoxin TXN 7295 NM_001244938 /// NM_003329 /// XM_006717276 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0033158 // regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015037 // peptide disulfide oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216610_at AB022847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB022847.1 /DEF=Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds. /FEA=mRNA /PROD=norepinephrine transporter isoform 2 /DB_XREF=gi:5360690 /UG=Hs.225971 Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds AB022847 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 216611_s_at AB022847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB022847.1 /DEF=Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds. /FEA=mRNA /PROD=norepinephrine transporter isoform 2 /DB_XREF=gi:5360690 /UG=Hs.225971 Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds AB022847 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 216612_x_at AK021988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021988.1 /DEF=Homo sapiens cDNA FLJ11926 fis, clone HEMBB1000374. /FEA=mRNA /DB_XREF=gi:10433297 /UG=Hs.306617 Homo sapiens cDNA FLJ11926 fis, clone HEMBB1000374 AK021988 216613_at AL050042 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050042.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566L0824 (from clone DKFZp566L0824). /FEA=mRNA /DB_XREF=gi:4884284 /UG=Hs.306309 Homo sapiens mRNA; cDNA DKFZp566L0824 (from clone DKFZp566L0824) AL050042 216614_at AL049988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049988.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F212 (from clone DKFZp564F212). /FEA=mRNA /DB_XREF=gi:4884239 /UG=Hs.306304 Homo sapiens mRNA; cDNA DKFZp564F212 (from clone DKFZp564F212) AL049988 216615_s_at AJ005205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ005205 /DEF=Homo sapiens 5HT3 gene for serotonin 3 receptor /FEA=mRNA_2 /DB_XREF=gi:7019744 /UG=Hs.2142 5-hydroxytryptamine (serotonin) receptor 3A AJ005205 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic HTR3A 3359 NM_000869 /// NM_001161772 /// NM_213621 /// NR_046363 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007586 // digestion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // non-traceable author statement /// 0005232 // serotonin-activated cation-selective channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation /// 0051378 // serotonin binding // inferred from direct assay 216616_at AL137428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137428.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761N1323 (from clone DKFZp761N1323). /FEA=mRNA /DB_XREF=gi:6807985 /UG=Hs.306459 Homo sapiens mRNA; cDNA DKFZp761N1323 (from clone DKFZp761N1323) AL137428 216617_s_at X98405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X98405.1 /DEF=H.sapiens mRNA for myelin associated glycoprotein, S-MAG. /FEA=mRNA /GEN=S-MAG /PROD=myelin associated glycoprotein /DB_XREF=gi:1403054 /UG=Hs.1780 myelin associated glycoprotein X98405 myelin associated glycoprotein MAG 4099 NM_001199216 /// NM_002361 /// NM_080600 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 216618_at AL117520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117520.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P2435 (from clone DKFZp434P2435). /FEA=mRNA /DB_XREF=gi:5912036 /UG=Hs.306348 Homo sapiens mRNA; cDNA DKFZp434P2435 (from clone DKFZp434P2435) AL117520 216619_at AL080161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080161.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N144 (from clone DKFZp434N144). /FEA=mRNA /DB_XREF=gi:5262623 /UG=Hs.210431 Homo sapiens mRNA; cDNA DKFZp434N144 (from clone DKFZp434N144) AL080161 GTP-binding protein 10 (putative) /// uncharacterized LOC101927446 GTPBP10 /// LOC101927446 85865 /// 101927446 NM_001042717 /// NM_033107 /// NR_110085 0006184 // GTP catabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216620_s_at AF009205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009205.1 /DEF=Homo sapiens clone L5 unknown mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:2454511 /UG=Hs.20695 Rho guanine nucleotide exchange factor (GEF) 10 AF009205 Rho guanine nucleotide exchange factor (GEF) 10 ARHGEF10 9639 NM_014629 /// XM_005266039 /// XM_005266040 /// XM_005266041 /// XM_005266042 /// XM_006716238 /// XM_006716239 /// XM_006716240 /// XM_006716241 /// XM_006725104 /// XM_006725105 /// XM_006725106 /// XM_006725107 /// XM_006725108 /// XM_006725109 /// XM_006725110 /// XM_006725111 0022011 // myelination in peripheral nervous system // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0033126 // positive regulation of GTP catabolic process // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction 216621_at AL050032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050032.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566F1224 (from clone DKFZp566F1224). /FEA=mRNA /DB_XREF=gi:4884272 /UG=Hs.306307 Homo sapiens mRNA; cDNA DKFZp566F1224 (from clone DKFZp566F1224) AL050032 216622_at AF029325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF029325.1 /DEF=Homo sapiens laminin beta-4 chain precursor (LAMB4) mRNA, alternatively spliced short variant, partial cds. /FEA=mRNA /GEN=LAMB4 /PROD=laminin beta-4 chain precursor /DB_XREF=gi:4003504 /UG=Hs.202688 laminin, beta 4 AF029325 laminin, beta 4 LAMB4 22798 NM_007356 /// XM_005250232 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 216623_x_at AK025084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025084.1 /DEF=Homo sapiens cDNA: FLJ21431 fis, clone COL04214, highly similar to HSU80736 Homo sapiens CAGF9 mRNA. /FEA=mRNA /DB_XREF=gi:10437527 /UG=Hs.110826 trinucleotide repeat containing 9 AK025084 TOX high mobility group box family member 3 TOX3 27324 NM_001080430 /// NM_001146188 /// XM_005255892 /// XM_005255893 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0034056 // estrogen response element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 216624_s_at Z69744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z69744 /DEF=H.sapiens ALL-1 gene exon 1 (and joined coding region) /FEA=CDS /DB_XREF=gi:1490270 /UG=Hs.199160 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) Z69744 lysine (K)-specific methyltransferase 2A KMT2A 4297 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 216625_at AL050032 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050032.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566F1224 (from clone DKFZp566F1224). /FEA=mRNA /DB_XREF=gi:4884272 /UG=Hs.306307 Homo sapiens mRNA; cDNA DKFZp566F1224 (from clone DKFZp566F1224) AL050032 216626_at AL050026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050026.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566C0224 (from clone DKFZp566C0224). /FEA=mRNA /DB_XREF=gi:4884265 /UG=Hs.306306 Homo sapiens mRNA; cDNA DKFZp566C0224 (from clone DKFZp566C0224) AL050026 216627_s_at U10473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U10473.1 /DEF=Human clone p4betaGT3 beta-1,4-galactosyltransferase mRNA, partial cds. /FEA=mRNA /PROD=beta-1,4-galactosyltransferase /DB_XREF=gi:500809 /UG=Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 U10473 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction 216628_at AL117447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117447.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586A0617 (from clone DKFZp586A0617). /FEA=mRNA /DB_XREF=gi:5911895 /UG=Hs.306342 Homo sapiens mRNA; cDNA DKFZp586A0617 (from clone DKFZp586A0617) AL117447 216629_at AC004493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004493 /DEF=Homo sapiens chromosome 16, cosmid clone 373C8 (LANL), complete sequence /FEA=CDS_1 /DB_XREF=gi:2996648 /UG=Hs.197114 RNA binding protein; AT-rich element binding factor AC004493 serine/arginine repetitive matrix 2 SRRM2 23524 NM_016333 /// XM_005255225 /// XM_005255226 /// XM_005255227 /// XM_006720872 /// XM_006720873 /// XM_006720874 /// XR_243270 /// XR_243271 /// XR_429640 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from direct assay 216630_at AL110190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110190.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J2116 (from clone DKFZp564J2116). /FEA=mRNA /DB_XREF=gi:5817104 /UG=Hs.306338 Homo sapiens mRNA; cDNA DKFZp564J2116 (from clone DKFZp564J2116) AL110190 216631_s_at X01634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X01634 /DEF=Human HLA-SB alpha 2 pseudogene (DP-alpha) /FEA=mRNA /DB_XREF=gi:36411 /UG=Hs.194764 major histocompatibility complex, class II, DP alpha 2 (pseudogene) X01634 major histocompatibility complex, class II, DP alpha 2 (pseudogene) /// HLA-DPA2 /// HLA-DPA2 216632_at AL080104 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080104.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566D153 (from clone DKFZp566D153). /FEA=mRNA /DB_XREF=gi:5262529 /UG=Hs.306322 Homo sapiens mRNA; cDNA DKFZp566D153 (from clone DKFZp566D153) AL080104 neuron navigator 3 NAV3 89795 NM_001024383 /// NM_014903 /// XM_005269215 /// XM_006719675 /// XM_006719676 /// XM_006719677 0008152 // metabolic process // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 216633_s_at AK022610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022610.1 /DEF=Homo sapiens cDNA FLJ12548 fis, clone NT2RM4000657, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11). /FEA=mRNA /DB_XREF=gi:10434099 /UG=Hs.193143 KIAA1069 protein AK022610 phospholipase C, eta 1 PLCH1 23007 NM_001130960 /// NM_001130961 /// NM_014996 /// XM_005247238 /// XM_005247239 /// XM_006713541 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050429 // calcium-dependent phospholipase C activity // inferred from direct assay 216634_at AK022610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022610.1 /DEF=Homo sapiens cDNA FLJ12548 fis, clone NT2RM4000657, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11). /FEA=mRNA /DB_XREF=gi:10434099 /UG=Hs.193143 KIAA1069 protein AK022610 phospholipase C, eta 1 PLCH1 23007 NM_001130960 /// NM_001130961 /// NM_014996 /// XM_005247238 /// XM_005247239 /// XM_006713541 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050429 // calcium-dependent phospholipase C activity // inferred from direct assay 216635_at AL050043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050043.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566M0524 (from clone DKFZp566M0524). /FEA=mRNA /DB_XREF=gi:4884285 /UG=Hs.306310 Homo sapiens mRNA; cDNA DKFZp566M0524 (from clone DKFZp566M0524) AL050043 216636_at AL050043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050043.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566M0524 (from clone DKFZp566M0524). /FEA=mRNA /DB_XREF=gi:4884285 /UG=Hs.306310 Homo sapiens mRNA; cDNA DKFZp566M0524 (from clone DKFZp566M0524) AL050043 216637_at AL117447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117447.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586A0617 (from clone DKFZp586A0617). /FEA=mRNA /DB_XREF=gi:5911895 /UG=Hs.306342 Homo sapiens mRNA; cDNA DKFZp586A0617 (from clone DKFZp586A0617) AL117447 216638_s_at S78505 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S78505.1 /DEF=Homo sapiens prolactin receptor mRNA, partial cds. /FEA=mRNA /PROD=prolactin receptor /DB_XREF=gi:999114 /UG=Hs.1906 prolactin receptor S78505 prolactin receptor PRLR 5618 NM_000949 /// NM_001204314 /// NM_001204315 /// NM_001204316 /// NM_001204317 /// NM_001204318 /// NR_037910 /// XM_006714484 0006694 // steroid biosynthetic process // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007566 // embryo implantation // traceable author statement /// 0007595 // lactation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // non-traceable author statement /// 0038161 // prolactin signaling pathway // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0042977 // activation of JAK2 kinase activity // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031904 // endosome lumen // traceable author statement 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004925 // prolactin receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042978 // ornithine decarboxylase activator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216639_at AL110206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110206.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586N2022 (from clone DKFZp586N2022). /FEA=mRNA /DB_XREF=gi:5817125 /UG=Hs.306339 Homo sapiens mRNA; cDNA DKFZp586N2022 (from clone DKFZp586N2022) AL110206 sushi-repeat containing protein, X-linked 2 SRPX2 27286 NM_014467 /// XM_005262121 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0048870 // cell motility // inferred from direct assay /// 0051965 // positive regulation of synapse assembly // inferred from direct assay /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0036458 // hepatocyte growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay 216640_s_at AK026926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026926.1 /DEF=Homo sapiens cDNA: FLJ23273 fis, clone HEP02611, highly similar to HSU79278 Human protein disulfide isomerase-related protein P5 mRNA. /FEA=mRNA /DB_XREF=gi:10439898 /UG=Hs.182429 protein disulfide isomerase-related protein AK026926 protein disulfide isomerase family A, member 6 PDIA6 10130 NM_001282704 /// NM_001282705 /// NM_001282706 /// NM_001282707 /// NM_005742 /// XM_005246145 /// XM_006711856 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043277 // apoptotic cell clearance // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 216641_s_at U58994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U58994 /DEF=Human ladinin (LAD) gene, complete cds /FEA=mRNA /DB_XREF=gi:4204914 /UG=Hs.18141 ladinin 1 U58994 ladinin 1 LAD1 3898 NM_005558 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // traceable author statement 216642_at AL110190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110190.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J2116 (from clone DKFZp564J2116). /FEA=mRNA /DB_XREF=gi:5817104 /UG=Hs.306338 Homo sapiens mRNA; cDNA DKFZp564J2116 (from clone DKFZp564J2116) AL110190 216643_at D25272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D25272.1 /DEF=Homo sapiens mRNA, clone:RES4-16. /FEA=mRNA /DB_XREF=gi:464187 /UG=Hs.174225 Homo sapiens mRNA, clone:RES4-16 D25272 216644_at AK000185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000185.1 /DEF=Homo sapiens cDNA FLJ20178 fis, clone COL09990. /FEA=mRNA /DB_XREF=gi:7020104 /UG=Hs.306389 Homo sapiens cDNA FLJ20178 fis, clone COL09990 AK000185 216645_at AL117663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117663.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L1824 (from clone DKFZp586L1824). /FEA=mRNA /DB_XREF=gi:5912259 /UG=Hs.306354 Homo sapiens mRNA; cDNA DKFZp586L1824 (from clone DKFZp586L1824) AL117663 216646_at L11372 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L11372.1 /DEF=Human protocadherin 43 mRNA, 3 end of cds for alternative splicing PC43-12. /FEA=mRNA /PROD=protocadherin 43 /DB_XREF=gi:307327 /UG=Hs.173310 protocadherin gamma subfamily C, 3 L11372 DNA replication and sister chromatid cohesion 1 DSCC1 79075 NM_024094 /// XM_005251065 0006260 // DNA replication // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034421 // post-translational protein acetylation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216647_at AL117663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117663.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L1824 (from clone DKFZp586L1824). /FEA=mRNA /DB_XREF=gi:5912259 /UG=Hs.306354 Homo sapiens mRNA; cDNA DKFZp586L1824 (from clone DKFZp586L1824) AL117663 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 216648_s_at AF072826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072826.1 /DEF=Homo sapiens Raf responsive zinc finger protein isoform (RREB1), partial cds. /FEA=mRNA /GEN=RREB1 /PROD=Raf responsive zinc finger protein isoform /DB_XREF=gi:3309594 /UG=Hs.171942 ras responsive element binding protein 1 AF072826 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216649_at AF072826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072826.1 /DEF=Homo sapiens Raf responsive zinc finger protein isoform (RREB1), partial cds. /FEA=mRNA /GEN=RREB1 /PROD=Raf responsive zinc finger protein isoform /DB_XREF=gi:3309594 /UG=Hs.171942 ras responsive element binding protein 1 AF072826 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216650_at AL008627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL008627 /DEF=Human DNA sequence from PAC 130G2 on chromosome 6p22.2-22.3. Contains ribosomal protein L29 pseudogene, ESTs and STSs /FEA=mRNA /DB_XREF=gi:2769539 /UG=Hs.166181 Human DNA sequence from PAC 130G2 on chromosome 6p22.2-22.3. Contains ribosomal protein L29 pseudogene, ESTs and STSs AL008627 RP1-130G2.1 216651_s_at X69936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X69936.1 /DEF=H.sapiens mRNA for glutamate decarboxylase. /FEA=CDS /GEN=GAD2 /PROD=glutamate decarboxylase /DB_XREF=gi:31757 /UG=Hs.170808 glutamate decarboxylase 2 (pancreatic islets and brain, 65kD) X69936 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) GAD2 2572 NM_000818 /// NM_001134366 0006540 // glutamate decarboxylation to succinate // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216652_s_at AL137673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137673.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0872 (from clone DKFZp434H0872). /FEA=mRNA /DB_XREF=gi:6807841 /UG=Hs.306454 Homo sapiens mRNA; cDNA DKFZp434H0872 (from clone DKFZp434H0872) AL137673 down-regulator of transcription 1, TBP-binding (negative cofactor 2) DR1 1810 NM_001938 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216653_at AL137673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137673.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0872 (from clone DKFZp434H0872). /FEA=mRNA /DB_XREF=gi:6807841 /UG=Hs.306454 Homo sapiens mRNA; cDNA DKFZp434H0872 (from clone DKFZp434H0872) AL137673 down-regulator of transcription 1, TBP-binding (negative cofactor 2) DR1 1810 NM_001938 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216654_at X71923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X71923.1 /DEF=H.sapiens XB gene for tenascin-X, exons 1 & 2. /FEA=mRNA /GEN=XB /PROD=tenascin-X precursor /DB_XREF=gi:394779 /UG=Hs.169886 tenascin XB X71923 tenascin XB TNXB 7148 NM_019105 /// NM_032470 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 216655_s_at AF041811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041811.2 /DEF=Homo sapiens ETS related protein-growth factor receptor tyrosine kinase fusion proteins (ETV6-NTRK3 fusion) mRNA, partial cds. /FEA=mRNA /GEN=ETV6-NTRK3 fusion /PROD=ETS related protein-growth factor receptortyrosine kinase fusion proteins /DB_XREF=gi:6274523 /UG=Hs.169081 ets variant gene 6 (TEL oncogene) AF041811 216656_at AF041811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041811.2 /DEF=Homo sapiens ETS related protein-growth factor receptor tyrosine kinase fusion proteins (ETV6-NTRK3 fusion) mRNA, partial cds. /FEA=mRNA /GEN=ETV6-NTRK3 fusion /PROD=ETS related protein-growth factor receptortyrosine kinase fusion proteins /DB_XREF=gi:6274523 /UG=Hs.169081 ets variant gene 6 (TEL oncogene) AF041811 216657_at U63332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U63332.1 /DEF=Human super cysteine rich protein mRNA, partial cds. /FEA=mRNA /PROD=super cysteine rich protein /DB_XREF=gi:1480862 /UG=Hs.169325 Human super cysteine rich protein mRNA, partial cds U63332 ataxin 3 ATXN3 4287 NM_001024631 /// NM_001127696 /// NM_001127697 /// NM_001164774 /// NM_001164776 /// NM_001164777 /// NM_001164778 /// NM_001164779 /// NM_001164780 /// NM_001164781 /// NM_001164782 /// NM_004993 /// NM_030660 /// NR_028453 /// NR_028454 /// NR_028455 /// NR_028456 /// NR_028457 /// NR_028458 /// NR_028459 /// NR_028460 /// NR_028461 /// NR_028462 /// NR_028463 /// NR_028464 /// NR_028465 /// NR_028466 /// NR_028467 /// NR_028468 /// NR_028469 /// NR_028470 /// NR_031765 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010810 // regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035520 // monoubiquitinated protein deubiquitination // inferred from sequence or structural similarity /// 0035640 // exploration behavior // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042405 // nuclear inclusion body // inferred from electronic annotation 0001012 // RNA polymerase II regulatory region DNA binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004843 // ubiquitin-specific protease activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 216658_at AK000185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000185.1 /DEF=Homo sapiens cDNA FLJ20178 fis, clone COL09990. /FEA=mRNA /DB_XREF=gi:7020104 /UG=Hs.306389 Homo sapiens cDNA FLJ20178 fis, clone COL09990 AK000185 216659_at J00146 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J00146.1 /DEF=Human dihydrofolate reductase pseudogene (psi-hd1). /FEA=mRNA /GEN=DHFRP1; DHFRP1 /DB_XREF=gi:182732 /UG=Hs.169235 Human dihydrofolate reductase pseudogene (psi-hd1) J00146 dihydrofolate reductase pseudogene LOC1720 1720 NR_033423 216660_at AK000145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000145.1 /DEF=Homo sapiens cDNA FLJ20138 fis, clone COL07172. /FEA=mRNA /DB_XREF=gi:7020041 /UG=Hs.306384 Homo sapiens cDNA FLJ20138 fis, clone COL07172 AK000145 myosin VIIB MYO7B 4648 NM_001080527 /// XM_006712539 0008152 // metabolic process // inferred from electronic annotation 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 216661_x_at M15331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M15331.1 /DEF=Human liver cytochrome P-450 S-mephenytoin 4-hydroxylase (P-450mp) mRNA, partial cds. /FEA=mRNA /GEN=CYP2C /DB_XREF=gi:181361 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 M15331 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 216662_at AK000145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000145.1 /DEF=Homo sapiens cDNA FLJ20138 fis, clone COL07172. /FEA=mRNA /DB_XREF=gi:7020041 /UG=Hs.306384 Homo sapiens cDNA FLJ20138 fis, clone COL07172 AK000145 myosin VIIB MYO7B 4648 NM_001080527 /// XM_006712539 0008152 // metabolic process // inferred from electronic annotation 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 216663_s_at AC002481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002481 /DEF=Human cosmid clone LUCA12 from 3p21.3 /FEA=CDS_1 /DB_XREF=gi:2340092 /UG=Hs.167380 BLu protein AC002481 zinc finger, MYND-type containing 10 ZMYND10 51364 NM_015896 /// XM_005265216 0036158 // outer dynein arm assembly // inferred from mutant phenotype /// 0036159 // inner dynein arm assembly // inferred from mutant phenotype /// 0044458 // motile cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216664_at AL133618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133618.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C2021 (from clone DKFZp434C2021). /FEA=mRNA /DB_XREF=gi:6599233 /UG=Hs.306443 Homo sapiens mRNA; cDNA DKFZp434C2021 (from clone DKFZp434C2021) AL133618 uncharacterized LOC101929148 LOC101929148 101929148 NR_110413 /// XR_250674 /// XR_424047 216665_s_at AL133618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133618.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C2021 (from clone DKFZp434C2021). /FEA=mRNA /DB_XREF=gi:6599233 /UG=Hs.306443 Homo sapiens mRNA; cDNA DKFZp434C2021 (from clone DKFZp434C2021) AL133618 uncharacterized LOC101929148 LOC101929148 101929148 NR_110413 /// XR_250674 /// XR_424047 216666_at AK000645 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000645.1 /DEF=Homo sapiens cDNA FLJ20638 fis, clone KAT02982, highly similar to SUIS_RABIT SUCRASE-ISOMALTASE. /FEA=mRNA /DB_XREF=gi:7020872 /UG=Hs.306399 Homo sapiens cDNA FLJ20638 fis, clone KAT02982, highly similar to SUIS_RABIT SUCRASE-ISOMALTASE AK000645 maltase-glucoamylase (alpha-glucosidase) LOC93432 93432 NM_001008748 /// NM_001293626 /// NR_003715 /// NR_003717 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004339 // glucan 1,4-alpha-glucosidase activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 216667_at X55989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X55989 /DEF=Human ECRP gene for eosinophil cationic related protein /FEA=mRNA /DB_XREF=gi:22940 /UG=Hs.166037 Human ECRP gene for eosinophil cationic related protein X55989 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene ECRP 643332 NR_033909 216668_at U63542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U63542.1 /DEF=Human putative FAP protein mRNA, partial cds. /FEA=mRNA /PROD=FAP protein /DB_XREF=gi:1890646 /UG=Hs.166101 Human putative FAP protein mRNA, partial cds U63542 /// poly(A) binding protein, cytoplasmic 1 pseudogene 1 PABPC1P1 /// PABPC1P1 216669_at AK000293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000293.1 /DEF=Homo sapiens cDNA FLJ20286 fis, clone HEP04358. /FEA=mRNA /DB_XREF=gi:7020278 /UG=Hs.306391 Homo sapiens cDNA FLJ20286 fis, clone HEP04358 AK000293 216670_at AL050220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050220.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J1923 (from clone DKFZp586J1923); partial cds. /FEA=mRNA /GEN=DKFZp586J1923 /PROD=hypothetical protein /DB_XREF=gi:4884461 /UG=Hs.165296 kallikrein 13 AL050220 kallikrein-related peptidase 13 KLK13 26085 NM_015596 0006508 // proteolysis // non-traceable author statement /// 0016485 // protein processing // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030141 // secretory granule // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from direct assay 216671_x_at U14383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U14383.1 /DEF=Human mucin (MUC8) mRNA, partial cds. /FEA=mRNA /GEN=MUC8 /PROD=mucin /DB_XREF=gi:606953 /UG=Hs.1607 mucin 8, tracheobronchial U14383 mucin 8 MUC8 100129528 XM_005266194 /// XM_005275730 /// XM_005276431 216672_s_at AL133024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133024.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E0922 (from clone DKFZp434E0922). /FEA=mRNA /DB_XREF=gi:6453581 /UG=Hs.306442 Homo sapiens mRNA; cDNA DKFZp434E0922 (from clone DKFZp434E0922) AL133024 myelin transcription factor 1-like MYT1L 23040 NM_015025 /// XM_006711862 /// XM_006711863 /// XM_006711864 /// XM_006711865 /// XM_006711866 /// XM_006711867 /// XM_006711868 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216673_at AF000990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF000990.1 /DEF=Homo sapiens testis-specific Testis Transcript Y 1 (TTY1) mRNA, partial cds. /FEA=mRNA /GEN=TTY1 /PROD=testis-specific Testis Transcript Y 1 /DB_XREF=gi:2580565 /UG=Hs.158344 testis-specific testis transcript Y 1 AF000990 testis-specific transcript, Y-linked 1 (non-protein coding) /// testis-specific transcript, Y-linked 1B (non-protein coding) TTTY1 /// TTTY1B 50858 /// 100101116 NR_001538 /// NR_003589 216674_at AL031848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031848 /DEF=Human DNA sequence from clone 202O8 on chromosome 1p36.11-36.31. Contains the 5 part of a gene for a novel rat Espin LIKE protein containing Ank repeats, the gene for the ortholog of rodent HES2 (Hairy and Enhacer of Split 2) and the 5 end of th... /FEA=CDS_3 /DB_XREF=gi:4914512 /UG=Hs.156042 hairy and enhancer of split (Drosophila) homolog 2 AL031848 hes family bHLH transcription factor 2 HES2 54626 NM_019089 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0008134 // transcription factor binding // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 216675_at AK000834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000834.1 /DEF=Homo sapiens cDNA FLJ20827 fis, clone ADKA03543. /FEA=mRNA /DB_XREF=gi:7021152 /UG=Hs.306409 Homo sapiens cDNA FLJ20827 fis, clone ADKA03543 AK000834 216676_x_at AC006293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006293 /DEF=Homo sapiens chromosome 19, cosmid F15658 /FEA=mRNA_3 /DB_XREF=gi:4106979 /UG=Hs.158310 Homo sapiens chromosome 19, cosmid F15658 AC006293 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 KIR3DL3 115653 NM_153443 /// XM_006725779 /// XM_006725780 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216677_at U20648 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U20648.1 /DEF=Human zinc finger protein (ZNF154) mRNA, partial cds. /FEA=mRNA /GEN=ZNF154 /PROD=zinc finger protein /DB_XREF=gi:676874 /UG=Hs.158299 zinc finger protein 154 (pHZ-92) U20648 216678_at AK000773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000773.1 /DEF=Homo sapiens cDNA FLJ20766 fis, clone COL07978. /FEA=mRNA /DB_XREF=gi:7021070 /UG=Hs.306403 Homo sapiens cDNA FLJ20766 fis, clone COL07978 AK000773 intraflagellar transport 122 homolog (Chlamydomonas) IFT122 55764 NM_001280541 /// NM_001280545 /// NM_001280546 /// NM_018262 /// NM_052985 /// NM_052989 /// NM_052990 /// XM_005247603 /// XM_005247604 /// XM_005247607 /// XM_005247608 /// XM_005247609 /// XM_005247610 /// XM_005247611 /// XM_006713689 /// XM_006713690 /// XM_006713691 /// XM_006713692 /// XM_006713693 /// XM_006713694 /// XM_006713695 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0035721 // intraciliary retrograde transport // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0060173 // limb development // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061512 // protein localization to cilium // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 216679_at AL137624 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137624.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M1812 (from clone DKFZp434M1812). /FEA=mRNA /DB_XREF=gi:6808420 /UG=Hs.306476 Homo sapiens mRNA; cDNA DKFZp434M1812 (from clone DKFZp434M1812) AL137624 DDR1 antisense RNA 1 (head to head) DDR1-AS1 414771 216680_s_at BC004264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004264.1 /DEF=Homo sapiens, Similar to EphB4, clone IMAGE:3611312, mRNA, partial cds. /FEA=mRNA /PROD=Similar to EphB4 /DB_XREF=gi:13279061 /UG=Hs.155227 EphB4 BC004264 EPH receptor B4 EPHB4 2050 NM_004444 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216681_at AK000353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000353.1 /DEF=Homo sapiens cDNA FLJ20346 fis, clone HEP13776, highly similar to S72904 APK1 antigen=MAb KI. /FEA=mRNA /DB_XREF=gi:7020382 /UG=Hs.155185 cytosolic ovarian carcinoma antigen 1 AK000353 216682_s_at AK021457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021457.1 /DEF=Homo sapiens cDNA FLJ11395 fis, clone HEMBA1000594. /FEA=mRNA /DB_XREF=gi:10432649 /UG=Hs.306595 Homo sapiens cDNA FLJ11395 fis, clone HEMBA1000594 AK021457 suppressor of Ty 20 homolog (S. cerevisiae) SUPT20H 55578 NM_001014286 /// NM_001278480 /// NM_001278481 /// NM_001278482 /// NM_017569 /// XM_005266447 /// XM_005266448 /// XM_005266449 /// XM_005266450 /// XM_005266451 /// XM_005266452 /// XM_005266453 /// XM_005266454 /// XM_005266455 /// XM_005266456 /// XM_005266457 /// XM_005266458 /// XM_005266460 /// XM_005266461 /// XM_005266462 /// XM_005266464 /// XM_005266465 /// XM_005266466 /// XM_005266467 /// XM_005266468 0006325 // chromatin organization // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000124 // SAGA complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216683_at AL353949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353949.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761P1114 (from clone DKFZp761P1114). /FEA=mRNA /DB_XREF=gi:7669990 /UG=Hs.306506 Homo sapiens mRNA; cDNA DKFZp761P1114 (from clone DKFZp761P1114) AL353949 216684_s_at AF257501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF257501.1 /DEF=Homo sapiens SYTSSX4v fusion protein (SSXTSSX4v fusion) mRNA, partial cds. /FEA=mRNA /GEN=SSXTSSX4v fusion /PROD=SYTSSX4v fusion protein /DB_XREF=gi:11127696 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome AF257501 synovial sarcoma translocation, chromosome 18 SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 216685_s_at AF216650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF216650.1 /DEF=Homo sapiens putative MTAP (MTAP) mRNA, partial cds, alternatively spliced. /FEA=mRNA /GEN=MTAP /PROD=MTAP /DB_XREF=gi:9082014 /UG=Hs.152817 methylthioadenosine phosphorylase AF216650 methylthioadenosine phosphorylase MTAP 4507 NM_002451 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0017061 // S-methyl-5-thioadenosine phosphorylase activity // traceable author statement 216686_at AL137717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137717.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434J1630 (from clone DKFZp434J1630). /FEA=mRNA /DB_XREF=gi:6808134 /UG=Hs.306469 Homo sapiens mRNA; cDNA DKFZp434J1630 (from clone DKFZp434J1630) AL137717 ankyrin repeat domain 36B pseudogene 2 ANKRD36BP2 645784 NR_015424 216687_x_at U06641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U06641.1 /DEF=Human UDP glucuronosyltransferase mRNA, partial cds. /FEA=mRNA /PROD=UDP glucuronosyltransferase /DB_XREF=gi:458398 /UG=Hs.150207 UDP glycosyltransferase 2 family, polypeptide B15 U06641 UDP glucuronosyltransferase 2 family, polypeptide B15 UGT2B15 7366 NM_001076 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0052695 // cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 216688_at AL137495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137495.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C2331 (from clone DKFZp434C2331). /FEA=mRNA /DB_XREF=gi:6808119 /UG=Hs.306468 Homo sapiens mRNA; cDNA DKFZp434C2331 (from clone DKFZp434C2331) AL137495 216689_x_at U62794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U62794.1 /DEF=Human CDC42 GAP-related protein mRNA, partial cds. /FEA=mRNA /PROD=CDC42 GAP-related protein /DB_XREF=gi:2326170 /UG=Hs.138860 Rho GTPase activating protein 1 U62794 Rho GTPase activating protein 1 ARHGAP1 392 NM_004308 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 216690_at AC005255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005255 /DEF=Homo sapiens chromosome 19, CIT-HSP-146e8 /FEA=CDS_4 /DB_XREF=gi:3289998 /UG=Hs.137573 olfactory receptor, family 7, subfamily C, member 1 AC005255 olfactory receptor, family 7, subfamily C, member 1 OR7C1 26664 NM_198944 /// XM_005259853 /// XM_006722723 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 216691_at AL137705 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137705.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A1422 (from clone DKFZp434A1422). /FEA=mRNA /DB_XREF=gi:6808069 /UG=Hs.306463 Homo sapiens mRNA; cDNA DKFZp434A1422 (from clone DKFZp434A1422) AL137705 216692_at AL137428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137428.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761N1323 (from clone DKFZp761N1323). /FEA=mRNA /DB_XREF=gi:6807985 /UG=Hs.306459 Homo sapiens mRNA; cDNA DKFZp761N1323 (from clone DKFZp761N1323) AL137428 216693_x_at AL133102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133102.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434C1722 (from clone DKFZp434C1722). /FEA=mRNA /DB_XREF=gi:6453585 /UG=Hs.127842 CGI-142 AL133102 hepatoma-derived growth factor, related protein 3 HDGFRP3 50810 NM_016073 /// XM_006720554 0008283 // cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 216694_at AL161956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161956.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761A17121 (from clone DKFZp761A17121). /FEA=mRNA /DB_XREF=gi:7328008 /UG=Hs.306492 Homo sapiens mRNA; cDNA DKFZp761A17121 (from clone DKFZp761A17121) AL161956 216695_s_at AF082559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF082559.1 /DEF=Homo sapiens truncated TRF1-interacting ankyrin-related ADP-ribose polymerase TT9 mRNA, alternatively spliced, partial cds. /FEA=mRNA /PROD=truncated TRF1-interacting ankyrin-relatedADP-ribose polymerase TT9 /DB_XREF=gi:3929224 /UG=Hs.131814 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase AF082559 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase TNKS 8658 NM_003747 /// XM_006716263 0000209 // protein polyubiquitination // inferred from direct assay /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0032210 // regulation of telomere maintenance via telomerase // inferred by curator /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from direct assay /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051225 // spindle assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0070212 // protein poly-ADP-ribosylation // inferred from direct assay /// 0070213 // protein auto-ADP-ribosylation // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000242 // pericentriolar material // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // traceable author statement 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216696_s_at U95090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U95090 /DEF=Homo sapiens chromosome 19 cosmid F19541 /FEA=CDS /DB_XREF=gi:2506085 /UG=Hs.128834 kidney and liver proline oxidase 1 U95090 proline dehydrogenase (oxidase) 2 PRODH2 58510 NM_021232 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006560 // proline metabolic process // inferred from electronic annotation /// 0006562 // proline catabolic process // inferred from electronic annotation /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation 0004657 // proline dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 216697_at AL161955 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161955.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0229 (from clone DKFZp434H0229). /FEA=mRNA /DB_XREF=gi:7328007 /UG=Hs.306491 Homo sapiens mRNA; cDNA DKFZp434H0229 (from clone DKFZp434H0229) AL161955 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 216698_x_at AF065854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF065854 /DEF=Homo sapiens OR7E12P pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3831591 /UG=Hs.120017 olfactory receptor, family 7, subfamily E, member 12 pseudogene AF065854 olfactory receptor, family 7, subfamily E, member 12 pseudogene OR7E12P 10821 NR_044999 216699_s_at L10038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L10038 /DEF=Homo sapiens pre-pro-protein for kallikrein gene, complete cds /FEA=CDS /DB_XREF=gi:292244 /UG=Hs.123107 kallikrein 1, renalpancreassalivary L10038 kallikrein 1 KLK1 3816 NM_002257 /// XM_005258900 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216700_at AL161955 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL161955.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H0229 (from clone DKFZp434H0229). /FEA=mRNA /DB_XREF=gi:7328007 /UG=Hs.306491 Homo sapiens mRNA; cDNA DKFZp434H0229 (from clone DKFZp434H0229) AL161955 trio Rho guanine nucleotide exchange factor TRIO 7204 NM_007118 /// XM_006714495 /// XR_241714 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation 216701_at AF005081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005081.1 /DEF=Homo sapiens skin-specific protein (xp32) mRNA, partial cds. /FEA=mRNA /GEN=xp32 /PROD=skin-specific protein /DB_XREF=gi:2589189 /UG=Hs.123091 Homo sapiens skin-specific protein (xp32) mRNA, partial cds AF005081 chromosome 1 open reading frame 68 C1orf68 100129271 NM_001024679 0008544 // epidermis development // non-traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 216702_x_at U82303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82303.1 /DEF=Homo sapiens unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1938329 /UG=Hs.123080 Homo sapiens unknown protein mRNA, partial cds U82303 216703_at AL162040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162040.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N199 (from clone DKFZp434N199). /FEA=mRNA /DB_XREF=gi:7328079 /UG=Hs.306493 Homo sapiens mRNA; cDNA DKFZp434N199 (from clone DKFZp434N199) AL162040 216704_at AL353949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353949.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761P1114 (from clone DKFZp761P1114). /FEA=mRNA /DB_XREF=gi:7669990 /UG=Hs.306506 Homo sapiens mRNA; cDNA DKFZp761P1114 (from clone DKFZp761P1114) AL353949 216705_s_at X02189 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X02189 /DEF=H.sapiens adenosine deaminase (ADA) gene 5 flanking region and exon 1 (and joined CDS) /FEA=CDS /DB_XREF=gi:28358 /UG=Hs.1217 adenosine deaminase X02189 adenosine deaminase ADA 100 NM_000022 /// XM_005260236 /// XM_006723679 /// XR_244129 0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002314 // germinal center B cell differentiation // inferred from electronic annotation /// 0002636 // positive regulation of germinal center formation // inferred from electronic annotation /// 0002686 // negative regulation of leukocyte migration // inferred from electronic annotation /// 0002906 // negative regulation of mature B cell apoptotic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006154 // adenosine catabolic process // inferred from direct assay /// 0006154 // adenosine catabolic process // inferred from sequence or structural similarity /// 0006157 // deoxyadenosine catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032261 // purine nucleotide salvage // inferred from mutant phenotype /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042323 // negative regulation of circadian sleep/wake cycle, non-REM sleep // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0043103 // hypoxanthine salvage // not recorded /// 0043278 // response to morphine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046061 // dATP catabolic process // inferred from electronic annotation /// 0046101 // hypoxanthine biosynthetic process // inferred from electronic annotation /// 0046103 // inosine biosynthetic process // inferred from direct assay /// 0046103 // inosine biosynthetic process // inferred from sequence or structural similarity /// 0046111 // xanthine biosynthetic process // inferred from electronic annotation /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060169 // negative regulation of adenosine receptor signaling pathway // inferred from direct assay /// 0060407 // negative regulation of penile erection // inferred from electronic annotation /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070256 // negative regulation of mucus secretion // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0060205 // cytoplasmic membrane-bounded vesicle lumen // inferred from electronic annotation 0001883 // purine nucleoside binding // inferred from electronic annotation /// 0004000 // adenosine deaminase activity // inferred from direct assay /// 0004000 // adenosine deaminase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216706_x_at M21388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M21388.1 /DEF=Human unproductively rearranged Ig mu-chain mRNA V-region (VD), 5 end, clone mu-3A1A. /FEA=mRNA /GEN=IGHM /DB_XREF=gi:185160 /UG=Hs.123017 Human unproductively rearranged Ig mu-chain mRNA V-region (VD), 5 end, clone mu-3A1A M21388 immunoglobulin heavy diversity 3-16 /// /// immunoglobulin heavy constant gamma 1 (G1m marker) /// src kinase associated phosphoprotein 2 IGHD3-16 /// IGHD3-16 /// IGHG1 /// SKAP2 3500 /// 8935 NM_003930 /// XM_005249901 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216707_at AL162044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162044.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L0812 (from clone DKFZp761L0812); partial cds. /FEA=mRNA /GEN=DKFZp761L0812 /PROD=hypothetical protein /DB_XREF=gi:7328083 /UG=Hs.306494 Homo sapiens mRNA; cDNA DKFZp761L0812 (from clone DKFZp761L0812); partial cds AL162044 216708_x_at D84143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D84143.1 /DEF=Human immunoglobulin (mAb59) light chain V region mRNA, partial sequence. /FEA=mRNA /PROD=immunoglobulin light chain V-J region /DB_XREF=gi:1255613 /UG=Hs.121508 Human immunoglobulin (mAb59) light chain V region mRNA, partial sequence D84143 216709_at AL162040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162040.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N199 (from clone DKFZp434N199). /FEA=mRNA /DB_XREF=gi:7328079 /UG=Hs.306493 Homo sapiens mRNA; cDNA DKFZp434N199 (from clone DKFZp434N199) AL162040 216710_x_at AL359578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359578.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547N163 (from clone DKFZp547N163). /FEA=mRNA /DB_XREF=gi:8655637 /UG=Hs.306511 Homo sapiens mRNA; cDNA DKFZp547N163 (from clone DKFZp547N163) AL359578 zinc finger protein 287 ZNF287 57336 NM_020653 /// XM_005256743 /// XM_006721561 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // /// 0006366 // transcription from RNA polymerase II promoter // /// 0014003 // oligodendrocyte development // /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216711_s_at M73444 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M73444.1 /DEF=Human CCG1p mRNA, 5 flank. /FEA=mRNA /DB_XREF=gi:179989 /UG=Hs.1179 TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 250kD M73444 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa TAF1 6872 NM_001286074 /// NM_004606 /// NM_138923 /// NR_104387 /// NR_104388 /// NR_104389 /// NR_104390 /// NR_104391 /// NR_104392 /// NR_104393 /// NR_104394 /// NR_104395 /// NR_104396 /// XM_005262295 /// XM_005262296 /// XM_005262297 /// XM_005262300 /// XM_006724680 /// XM_006724681 /// XM_006724682 0000080 // mitotic G1 phase // inferred from genetic interaction /// 0000117 // regulation of transcription involved in G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from sequence or structural similarity /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 216712_at AL359557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359557.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762O1415 (from clone DKFZp762O1415). /FEA=mRNA /DB_XREF=gi:8655612 /UG=Hs.306508 Homo sapiens mRNA; cDNA DKFZp762O1415 (from clone DKFZp762O1415) AL359557 solute carrier family 25, member 30 SLC25A30 253512 NM_001010875 /// NM_001286806 /// NM_001286807 /// XM_005266321 /// XM_005266322 /// XM_005266327 /// XM_006719793 /// XM_006719794 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 216713_at AL049325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049325.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D036 (from clone DKFZp564D036). /FEA=mRNA /DB_XREF=gi:4500098 /UG=Hs.112493 Homo sapiens mRNA; cDNA DKFZp564D036 (from clone DKFZp564D036) AL049325 KRIT1, ankyrin repeat containing KRIT1 889 NM_001013406 /// NM_004912 /// NM_194454 /// NM_194455 /// NM_194456 /// XM_005250660 /// XM_005250662 /// XM_005250663 /// XM_005250664 /// XM_005250665 /// XM_005250666 /// XM_005250667 /// XM_005250668 /// XM_005250669 /// XM_006716160 /// XM_006716161 /// XM_006716162 /// XM_006716163 /// XM_006716164 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 216714_at Z77651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z77651.1 /DEF=H.sapiens mRNA for CC-chemokine (sequence variant). /FEA=mRNA /PROD=CC-chemokine /DB_XREF=gi:4128134 /UG=Hs.11383 small inducible cytokine subfamily A (Cys-Cys), member 13 Z77651 chemokine (C-C motif) ligand 13 CCL13 6357 NM_005408 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay 216715_at AL080315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080315 /DEF=Human DNA sequence from clone RP1-6P5 on chromosome 6 Contains a pseudogene similar to EEF1D (eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)), a pseudogene similar to ribosomal protein L21, ESTs, STSs and GSSs /FEA=CDS_1 /DB_XREF=gi:7838240 /UG=Hs.306507 Human DNA sequence from clone RP1-6P5 on chromosome 6 Contains a pseudogene similar to EEF1D (eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)), a pseudogene similar to ribosomal protein L21, ESTs, STSs and GSSs AL080315 eukaryotic translation elongation factor 1 delta pseudogene 5 /// EEF1DP5 /// EEF1DP5 216716_at U15197 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U15197.1 /DEF=Human histo-blood group ABO protein mRNA, partial 3 UTR sequence. /FEA=mRNA /GEN=ABO /DB_XREF=gi:595854 /UG=Hs.113271 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) U15197 216717_at AK021457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021457.1 /DEF=Homo sapiens cDNA FLJ11395 fis, clone HEMBA1000594. /FEA=mRNA /DB_XREF=gi:10432649 /UG=Hs.306595 Homo sapiens cDNA FLJ11395 fis, clone HEMBA1000594 AK021457 suppressor of Ty 20 homolog (S. cerevisiae) SUPT20H 55578 NM_001014286 /// NM_001278480 /// NM_001278481 /// NM_001278482 /// NM_017569 /// XM_005266447 /// XM_005266448 /// XM_005266449 /// XM_005266450 /// XM_005266451 /// XM_005266452 /// XM_005266453 /// XM_005266454 /// XM_005266455 /// XM_005266456 /// XM_005266457 /// XM_005266458 /// XM_005266460 /// XM_005266461 /// XM_005266462 /// XM_005266464 /// XM_005266465 /// XM_005266466 /// XM_005266467 /// XM_005266468 0006325 // chromatin organization // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000124 // SAGA complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216718_at AF005082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005082.1 /DEF=Homo sapiens skin-specific protein (xp33) mRNA, partial cds. /FEA=mRNA /GEN=xp33 /PROD=skin-specific protein /DB_XREF=gi:2589191 /UG=Hs.113261 Homo sapiens skin-specific protein (xp33) mRNA, partial cds AF005082 long intergenic non-protein coding RNA 302 LINC00302 388699 216719_s_at AL359563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359563.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D0326 (from clone DKFZp434D0326). /FEA=mRNA /DB_XREF=gi:8655619 /UG=Hs.306509 Homo sapiens mRNA; cDNA DKFZp434D0326 (from clone DKFZp434D0326) AL359563 RP11-286E11.2 216720_at AL359563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359563.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D0326 (from clone DKFZp434D0326). /FEA=mRNA /DB_XREF=gi:8655619 /UG=Hs.306509 Homo sapiens mRNA; cDNA DKFZp434D0326 (from clone DKFZp434D0326) AL359563 cytochrome P450, family 2, subfamily U, polypeptide 1 CYP2U1 113612 NM_183075 /// XM_005262717 /// XM_005262720 0006805 // xenobiotic metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 216721_at AL359557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359557.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762O1415 (from clone DKFZp762O1415). /FEA=mRNA /DB_XREF=gi:8655612 /UG=Hs.306508 Homo sapiens mRNA; cDNA DKFZp762O1415 (from clone DKFZp762O1415) AL359557 solute carrier family 25, member 30 SLC25A30 253512 NM_001010875 /// NM_001286806 /// NM_001286807 /// XM_005266321 /// XM_005266322 /// XM_005266327 /// XM_006719793 /// XM_006719794 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 216722_at AF164963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF164963.1 /DEF=Homo sapiens tumor antigen NA88-A pseudogene, complete sequence. /FEA=mRNA /DB_XREF=gi:5901726 /UG=Hs.306576 Homo sapiens tumor antigen NA88-A pseudogene, complete sequence AF164963 VENT homeobox pseudogene 1 VENTXP1 139538 NR_001559 216723_at AL390157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390157.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D179 (from clone DKFZp434D179). /FEA=mRNA /DB_XREF=gi:9368847 /UG=Hs.306520 Homo sapiens mRNA; cDNA DKFZp434D179 (from clone DKFZp434D179) AL390157 216724_at AL359602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359602.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547D146 (from clone DKFZp547D146). /FEA=mRNA /DB_XREF=gi:8655670 /UG=Hs.306514 Homo sapiens mRNA; cDNA DKFZp547D146 (from clone DKFZp547D146) AL359602 doublecortin-like kinase 2 DCLK2 166614 NM_001040260 /// NM_001040261 /// NM_152619 /// NR_036614 /// XM_005262785 /// XM_005262786 /// XR_244621 0006468 // protein phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 216725_at AL359602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359602.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547D146 (from clone DKFZp547D146). /FEA=mRNA /DB_XREF=gi:8655670 /UG=Hs.306514 Homo sapiens mRNA; cDNA DKFZp547D146 (from clone DKFZp547D146) AL359602 doublecortin-like kinase 2 DCLK2 166614 NM_001040260 /// NM_001040261 /// NM_152619 /// NR_036614 /// XM_005262785 /// XM_005262786 /// XR_244621 0006468 // protein phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 216726_at AF164963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF164963.1 /DEF=Homo sapiens tumor antigen NA88-A pseudogene, complete sequence. /FEA=mRNA /DB_XREF=gi:5901726 /UG=Hs.306576 Homo sapiens tumor antigen NA88-A pseudogene, complete sequence AF164963 VENT homeobox pseudogene 1 VENTXP1 139538 NR_001559 216727_at AF034187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF034187.1 /DEF=Homo sapiens clone 2.2H12 Ndr SerThr kinase-like protein mRNA, partial cds. /FEA=mRNA /PROD=Ndr SerThr kinase-like protein /DB_XREF=gi:5757628 /UG=Hs.306543 Homo sapiens clone 2.2H12 Ndr SerThr kinase-like protein mRNA, partial cds AF034187 serine/threonine kinase 38 STK38 11329 NM_007271 /// XM_005248839 /// XM_006714988 /// XM_006714989 /// XM_006714990 0006464 // cellular protein modification process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216728_at AL390157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390157.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D179 (from clone DKFZp434D179). /FEA=mRNA /DB_XREF=gi:9368847 /UG=Hs.306520 Homo sapiens mRNA; cDNA DKFZp434D179 (from clone DKFZp434D179) AL390157 216729_at AK025388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025388.1 /DEF=Homo sapiens cDNA: FLJ21735 fis, clone COLF3350. /FEA=mRNA /DB_XREF=gi:10437892 /UG=Hs.306808 Homo sapiens cDNA: FLJ21735 fis, clone COLF3350 AK025388 216730_at AK024561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024561.1 /DEF=Homo sapiens cDNA: FLJ20908 fis, clone ADSE00417. /FEA=mRNA /DB_XREF=gi:10436870 /UG=Hs.306689 Homo sapiens cDNA: FLJ20908 fis, clone ADSE00417 AK024561 216731_s_at AK023690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023690.1 /DEF=Homo sapiens cDNA FLJ13628 fis, clone PLACE1011054. /FEA=mRNA /DB_XREF=gi:10435692 /UG=Hs.306656 Homo sapiens cDNA FLJ13628 fis, clone PLACE1011054 AK023690 216732_at AK023690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023690.1 /DEF=Homo sapiens cDNA FLJ13628 fis, clone PLACE1011054. /FEA=mRNA /DB_XREF=gi:10435692 /UG=Hs.306656 Homo sapiens cDNA FLJ13628 fis, clone PLACE1011054 AK023690 216733_s_at X86401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X86401.1 /DEF=H.sapiens mRNA for L-arginine:glycine amidinotransferase. /FEA=mRNA /PROD=L-arginine: glycine amidinotransferase /DB_XREF=gi:791048 /UG=Hs.75335 glycine amidinotransferase (L-arginine:glycine amidinotransferase) X86401 glycine amidinotransferase (L-arginine:glycine amidinotransferase) GATM 2628 NM_001482 /// XR_424635 /// XR_429525 /// XR_433091 0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015067 // amidinotransferase activity // inferred from electronic annotation /// 0015068 // glycine amidinotransferase activity // inferred from direct assay /// 0015068 // glycine amidinotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation 216734_s_at X68829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X68829.1 /DEF=H.sapiens mRNA for MDR15 protein. /FEA=mRNA /PROD=MDCR15 protein /DB_XREF=gi:840783 /UG=Hs.113916 Burkitt lymphoma receptor 1, GTP-binding protein X68829 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation 216735_x_at AK024553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024553.1 /DEF=Homo sapiens cDNA: FLJ20900 fis, clone ADKA03593. /FEA=mRNA /DB_XREF=gi:10436861 /UG=Hs.306687 Homo sapiens cDNA: FLJ20900 fis, clone ADKA03593 AK024553 216736_at AK024515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024515.1 /DEF=Homo sapiens cDNA: FLJ20862 fis, clone ADKA01780. /FEA=mRNA /DB_XREF=gi:10436816 /UG=Hs.306680 Homo sapiens cDNA: FLJ20862 fis, clone ADKA01780 AK024515 transmembrane 6 superfamily member 2 TM6SF2 53345 NM_001001524 /// NM_203510 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216737_at AK024525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024525.1 /DEF=Homo sapiens cDNA: FLJ20872 fis, clone ADKA02604. /FEA=mRNA /DB_XREF=gi:10436827 /UG=Hs.306683 Homo sapiens cDNA: FLJ20872 fis, clone ADKA02604 AK024525 216738_at AK024553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024553.1 /DEF=Homo sapiens cDNA: FLJ20900 fis, clone ADKA03593. /FEA=mRNA /DB_XREF=gi:10436861 /UG=Hs.306687 Homo sapiens cDNA: FLJ20900 fis, clone ADKA03593 AK024553 216739_at AK024527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024527.1 /DEF=Homo sapiens cDNA: FLJ20874 fis, clone ADKA02818. /FEA=mRNA /DB_XREF=gi:10436829 /UG=Hs.306684 Homo sapiens cDNA: FLJ20874 fis, clone ADKA02818 AK024527 216740_at AK024851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024851.1 /DEF=Homo sapiens cDNA: FLJ21198 fis, clone COL00220. /FEA=mRNA /DB_XREF=gi:10437259 /UG=Hs.306707 Homo sapiens cDNA: FLJ21198 fis, clone COL00220 AK024851 216741_at AK024568 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024568.1 /DEF=Homo sapiens cDNA: FLJ20915 fis, clone ADSE00692. /FEA=mRNA /DB_XREF=gi:10436878 /UG=Hs.306691 Homo sapiens cDNA: FLJ20915 fis, clone ADSE00692 AK024568 216742_at AK024561 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024561.1 /DEF=Homo sapiens cDNA: FLJ20908 fis, clone ADSE00417. /FEA=mRNA /DB_XREF=gi:10436870 /UG=Hs.306689 Homo sapiens cDNA: FLJ20908 fis, clone ADSE00417 AK024561 216743_at AK024915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024915.1 /DEF=Homo sapiens cDNA: FLJ21262 fis, clone COL01494. /FEA=mRNA /DB_XREF=gi:10437330 /UG=Hs.306727 Homo sapiens cDNA: FLJ21262 fis, clone COL01494 AK024915 216744_at AK024615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024615.1 /DEF=Homo sapiens cDNA: FLJ20962 fis, clone ADSH00804. /FEA=mRNA /DB_XREF=gi:10436931 /UG=Hs.306698 Homo sapiens cDNA: FLJ20962 fis, clone ADSH00804 AK024615 216745_x_at AK024606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024606.1 /DEF=Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979. /FEA=mRNA /DB_XREF=gi:10436920 /UG=Hs.306697 Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979 AK024606 216746_at AK024606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024606.1 /DEF=Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979. /FEA=mRNA /DB_XREF=gi:10436920 /UG=Hs.306697 Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979 AK024606 216747_at AK024871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024871.1 /DEF=Homo sapiens cDNA: FLJ21218 fis, clone COL00537. /FEA=mRNA /DB_XREF=gi:10437282 /UG=Hs.306712 Homo sapiens cDNA: FLJ21218 fis, clone COL00537 AK024871 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 216748_at AK024890 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024890.1 /DEF=Homo sapiens cDNA: FLJ21237 fis, clone COL01114. /FEA=mRNA /DB_XREF=gi:10437303 /UG=Hs.306720 Homo sapiens cDNA: FLJ21237 fis, clone COL01114 AK024890 pyrin and HIN domain family, member 1 PYHIN1 149628 NM_152501 /// NM_198928 /// NM_198929 /// NM_198930 /// XM_005244930 /// XM_006711191 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 216749_at AK024851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024851.1 /DEF=Homo sapiens cDNA: FLJ21198 fis, clone COL00220. /FEA=mRNA /DB_XREF=gi:10437259 /UG=Hs.306707 Homo sapiens cDNA: FLJ21198 fis, clone COL00220 AK024851 216750_at AK024871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024871.1 /DEF=Homo sapiens cDNA: FLJ21218 fis, clone COL00537. /FEA=mRNA /DB_XREF=gi:10437282 /UG=Hs.306712 Homo sapiens cDNA: FLJ21218 fis, clone COL00537 AK024871 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 216751_at AK024879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024879.1 /DEF=Homo sapiens cDNA: FLJ21226 fis, clone COL00721. /FEA=mRNA /DB_XREF=gi:10437291 /UG=Hs.306715 Homo sapiens cDNA: FLJ21226 fis, clone COL00721 AK024879 216752_at AK025026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025026.1 /DEF=Homo sapiens cDNA: FLJ21373 fis, clone COL03214. /FEA=mRNA /DB_XREF=gi:10437461 /UG=Hs.306747 Homo sapiens cDNA: FLJ21373 fis, clone COL03214 AK025026 phosphoinositide-3-kinase, regulatory subunit 4 PIK3R4 30849 NM_014602 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216753_at AK025152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025152.1 /DEF=Homo sapiens cDNA: FLJ21499 fis, clone COL05634. /FEA=mRNA /DB_XREF=gi:10437612 /UG=Hs.306773 Homo sapiens cDNA: FLJ21499 fis, clone COL05634 AK025152 216754_at AK025388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025388.1 /DEF=Homo sapiens cDNA: FLJ21735 fis, clone COLF3350. /FEA=mRNA /DB_XREF=gi:10437892 /UG=Hs.306808 Homo sapiens cDNA: FLJ21735 fis, clone COLF3350 AK025388 216755_at AK024945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024945.1 /DEF=Homo sapiens cDNA: FLJ21292 fis, clone COL01969. /FEA=mRNA /DB_XREF=gi:10437367 /UG=Hs.306732 Homo sapiens cDNA: FLJ21292 fis, clone COL01969 AK024945 oxysterol binding protein-like 10 OSBPL10 114884 NM_001174060 /// NM_017784 /// XM_005264843 /// XM_005264844 /// XM_005264845 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 216756_at AK024995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024995.1 /DEF=Homo sapiens cDNA: FLJ21342 fis, clone COL02673. /FEA=mRNA /DB_XREF=gi:10437426 /UG=Hs.306739 Homo sapiens cDNA: FLJ21342 fis, clone COL02673 AK024995 216757_at AK024995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024995.1 /DEF=Homo sapiens cDNA: FLJ21342 fis, clone COL02673. /FEA=mRNA /DB_XREF=gi:10437426 /UG=Hs.306739 Homo sapiens cDNA: FLJ21342 fis, clone COL02673 AK024995 216758_at AK025038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025038.1 /DEF=Homo sapiens cDNA: FLJ21385 fis, clone COL03356. /FEA=mRNA /DB_XREF=gi:10437474 /UG=Hs.306750 Homo sapiens cDNA: FLJ21385 fis, clone COL03356 AK025038 216759_at AK025029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025029.1 /DEF=Homo sapiens cDNA: FLJ21376 fis, clone COL03231. /FEA=mRNA /DB_XREF=gi:10437464 /UG=Hs.306748 Homo sapiens cDNA: FLJ21376 fis, clone COL03231 AK025029 HRAS-like suppressor 2 HRASLS2 54979 NM_017878 0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216760_at AK025029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025029.1 /DEF=Homo sapiens cDNA: FLJ21376 fis, clone COL03231. /FEA=mRNA /DB_XREF=gi:10437464 /UG=Hs.306748 Homo sapiens cDNA: FLJ21376 fis, clone COL03231 AK025029 HRAS-like suppressor 2 HRASLS2 54979 NM_017878 0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 216761_at AK025038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025038.1 /DEF=Homo sapiens cDNA: FLJ21385 fis, clone COL03356. /FEA=mRNA /DB_XREF=gi:10437474 /UG=Hs.306750 Homo sapiens cDNA: FLJ21385 fis, clone COL03356 AK025038 216762_at AK025097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025097.1 /DEF=Homo sapiens cDNA: FLJ21444 fis, clone COL04437. /FEA=mRNA /DB_XREF=gi:10437544 /UG=Hs.306764 Homo sapiens cDNA: FLJ21444 fis, clone COL04437 AK025097 216763_at AK025097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025097.1 /DEF=Homo sapiens cDNA: FLJ21444 fis, clone COL04437. /FEA=mRNA /DB_XREF=gi:10437544 /UG=Hs.306764 Homo sapiens cDNA: FLJ21444 fis, clone COL04437 AK025097 216764_at AK025191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025191.1 /DEF=Homo sapiens cDNA: FLJ21538 fis, clone COL06151. /FEA=mRNA /DB_XREF=gi:10437654 /UG=Hs.306783 Homo sapiens cDNA: FLJ21538 fis, clone COL06151 AK025191 216765_at AK025177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025177.1 /DEF=Homo sapiens cDNA: FLJ21524 fis, clone COL05921. /FEA=mRNA /DB_XREF=gi:10437640 /UG=Hs.306778 Homo sapiens cDNA: FLJ21524 fis, clone COL05921 AK025177 mitogen-activated protein kinase kinase 5 MAP2K5 5607 NM_001206804 /// NM_002757 /// NM_145160 /// NM_145161 /// NM_145162 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051247 // positive regulation of protein metabolic process // inferred from sequence or structural similarity /// 0060761 // negative regulation of response to cytokine stimulus // inferred from sequence or structural similarity /// 0070375 // ERK5 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from sequence or structural similarity /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216766_at AK025152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025152.1 /DEF=Homo sapiens cDNA: FLJ21499 fis, clone COL05634. /FEA=mRNA /DB_XREF=gi:10437612 /UG=Hs.306773 Homo sapiens cDNA: FLJ21499 fis, clone COL05634 AK025152 216767_at AK025363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025363.1 /DEF=Homo sapiens cDNA: FLJ21710 fis, clone COL10087. /FEA=mRNA /DB_XREF=gi:10437865 /UG=Hs.306807 Homo sapiens cDNA: FLJ21710 fis, clone COL10087 AK025363 216768_x_at AK025188 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025188.1 /DEF=Homo sapiens cDNA: FLJ21535 fis, clone COL06131. /FEA=mRNA /DB_XREF=gi:10437651 /UG=Hs.306781 Homo sapiens cDNA: FLJ21535 fis, clone COL06131 AK025188 tetratricopeptide repeat domain 38 TTC38 55020 NM_017931 /// XR_244380 216769_x_at AK025180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025180.1 /DEF=Homo sapiens cDNA: FLJ21527 fis, clone COL05961. /FEA=mRNA /DB_XREF=gi:10437643 /UG=Hs.306779 Homo sapiens cDNA: FLJ21527 fis, clone COL05961 AK025180 216770_at AK025325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025325.1 /DEF=Homo sapiens cDNA: FLJ21672 fis, clone COL09025. /FEA=mRNA /DB_XREF=gi:10437818 /UG=Hs.306801 Homo sapiens cDNA: FLJ21672 fis, clone COL09025 AK025325 216771_at AK025194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025194.1 /DEF=Homo sapiens cDNA: FLJ21541 fis, clone COL06166. /FEA=mRNA /DB_XREF=gi:10437657 /UG=Hs.306784 Homo sapiens cDNA: FLJ21541 fis, clone COL06166 AK025194 216772_at AK025194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025194.1 /DEF=Homo sapiens cDNA: FLJ21541 fis, clone COL06166. /FEA=mRNA /DB_XREF=gi:10437657 /UG=Hs.306784 Homo sapiens cDNA: FLJ21541 fis, clone COL06166 AK025194 216773_at AK025191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025191.1 /DEF=Homo sapiens cDNA: FLJ21538 fis, clone COL06151. /FEA=mRNA /DB_XREF=gi:10437654 /UG=Hs.306783 Homo sapiens cDNA: FLJ21538 fis, clone COL06151 AK025191 216774_at AK025325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025325.1 /DEF=Homo sapiens cDNA: FLJ21672 fis, clone COL09025. /FEA=mRNA /DB_XREF=gi:10437818 /UG=Hs.306801 Homo sapiens cDNA: FLJ21672 fis, clone COL09025 AK025325 216775_at AK025301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025301.1 /DEF=Homo sapiens cDNA: FLJ21648 fis, clone COL08469. /FEA=mRNA /DB_XREF=gi:10437789 /UG=Hs.306797 Homo sapiens cDNA: FLJ21648 fis, clone COL08469 AK025301 ubiquitin specific peptidase 53 USP53 54532 NM_019050 /// XM_005263073 /// XM_005263074 /// XM_005263075 /// XM_005263076 /// XM_005263077 /// XM_005263078 /// XM_006714240 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 216776_at AK025206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025206.1 /DEF=Homo sapiens cDNA: FLJ21553 fis, clone COL06329. /FEA=mRNA /DB_XREF=gi:10437671 /UG=Hs.306786 Homo sapiens cDNA: FLJ21553 fis, clone COL06329 AK025206 216777_at AK025206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025206.1 /DEF=Homo sapiens cDNA: FLJ21553 fis, clone COL06329. /FEA=mRNA /DB_XREF=gi:10437671 /UG=Hs.306786 Homo sapiens cDNA: FLJ21553 fis, clone COL06329 AK025206 216778_s_at Z22780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22780.1 /DEF=H.sapiens cylicin mRNA. /FEA=mRNA /PROD=cylicin /DB_XREF=gi:396104 /UG=Hs.307358 cylicin, basic protein of sperm head cytoskeleton 1 Z22780 cylicin, basic protein of sperm head cytoskeleton 1 CYLC1 1538 NM_001271680 /// NM_021118 /// XM_005262086 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0033150 // cytoskeletal calyx // inferred from electronic annotation /// 0043159 // acrosomal matrix // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation 216779_at Z22780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22780.1 /DEF=H.sapiens cylicin mRNA. /FEA=mRNA /PROD=cylicin /DB_XREF=gi:396104 /UG=Hs.307358 cylicin, basic protein of sperm head cytoskeleton 1 Z22780 cylicin, basic protein of sperm head cytoskeleton 1 CYLC1 1538 NM_001271680 /// NM_021118 /// XM_005262086 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0033150 // cytoskeletal calyx // inferred from electronic annotation /// 0043159 // acrosomal matrix // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation 216780_at AK025564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025564.1 /DEF=Homo sapiens cDNA: FLJ21911 fis, clone HEP03855. /FEA=mRNA /DB_XREF=gi:10438116 /UG=Hs.306816 Homo sapiens cDNA: FLJ21911 fis, clone HEP03855 AK025564 zinc finger protein 443 ZNF443 10224 NM_005815 /// XM_005259705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216781_at AB051538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051538.1 /DEF=Homo sapiens mRNA for KIAA1751 protein, partial cds. /FEA=mRNA /GEN=KIAA1751 /PROD=KIAA1751 protein /DB_XREF=gi:12698046 /UG=Hs.307002 Homo sapiens mRNA for KIAA1751 protein, partial cds AB051538 KIAA1751 KIAA1751 85452 NM_001003808 /// NM_001080484 /// XM_003119800 /// XM_005244811 /// XM_006710997 /// XM_006710998 216782_at AK026679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026679.1 /DEF=Homo sapiens cDNA: FLJ23026 fis, clone LNG01738. /FEA=mRNA /DB_XREF=gi:10439585 /UG=Hs.306863 Homo sapiens cDNA: FLJ23026 fis, clone LNG01738 AK026679 216783_at AK025552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025552.1 /DEF=Homo sapiens cDNA: FLJ21899 fis, clone HEP03467. /FEA=mRNA /DB_XREF=gi:10438101 /UG=Hs.306815 Homo sapiens cDNA: FLJ21899 fis, clone HEP03467 AK025552 216784_at AK025422 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025422.1 /DEF=Homo sapiens cDNA: FLJ21769 fis, clone COLF7354. /FEA=mRNA /DB_XREF=gi:10437930 /UG=Hs.306810 Homo sapiens cDNA: FLJ21769 fis, clone COLF7354 AK025422 216785_at AK026273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026273.1 /DEF=Homo sapiens cDNA: FLJ22620 fis, clone HSI05629. /FEA=mRNA /DB_XREF=gi:10439077 /UG=Hs.306834 Homo sapiens cDNA: FLJ22620 fis, clone HSI05629 AK026273 216786_at AK026667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026667.1 /DEF=Homo sapiens cDNA: FLJ23014 fis, clone LNG00806. /FEA=mRNA /DB_XREF=gi:10439568 /UG=Hs.306862 Homo sapiens cDNA: FLJ23014 fis, clone LNG00806 AK026667 family with sequence similarity 224, member A (non-protein coding) FAM224A 401630 NR_002161 216787_at AK026273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026273.1 /DEF=Homo sapiens cDNA: FLJ22620 fis, clone HSI05629. /FEA=mRNA /DB_XREF=gi:10439077 /UG=Hs.306834 Homo sapiens cDNA: FLJ22620 fis, clone HSI05629 AK026273 216788_at AK025564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025564.1 /DEF=Homo sapiens cDNA: FLJ21911 fis, clone HEP03855. /FEA=mRNA /DB_XREF=gi:10438116 /UG=Hs.306816 Homo sapiens cDNA: FLJ21911 fis, clone HEP03855 AK025564 zinc finger protein 443 ZNF443 10224 NM_005815 /// XM_005259705 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216789_at AK026439 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026439.1 /DEF=Homo sapiens cDNA: FLJ22786 fis, clone KAIA2150. /FEA=mRNA /DB_XREF=gi:10439304 /UG=Hs.306848 Homo sapiens cDNA: FLJ22786 fis, clone KAIA2150 AK026439 216790_at AK026465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026465.1 /DEF=Homo sapiens cDNA: FLJ22812 fis, clone KAIA2955. /FEA=mRNA /DB_XREF=gi:10439335 /UG=Hs.306853 Homo sapiens cDNA: FLJ22812 fis, clone KAIA2955 AK026465 216791_at AK026449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026449.1 /DEF=Homo sapiens cDNA: FLJ22796 fis, clone KAIA2544. /FEA=mRNA /DB_XREF=gi:10439318 /UG=Hs.306850 Homo sapiens cDNA: FLJ22796 fis, clone KAIA2544 AK026449 216792_at AK026867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026867.1 /DEF=Homo sapiens cDNA: FLJ23214 fis, clone ADSU01585. /FEA=mRNA /DB_XREF=gi:10439827 /UG=Hs.306891 Homo sapiens cDNA: FLJ23214 fis, clone ADSU01585 AK026867 216793_x_at AK026856 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026856.1 /DEF=Homo sapiens cDNA: FLJ23203 fis, clone ADKA02487. /FEA=mRNA /DB_XREF=gi:10439812 /UG=Hs.306889 Homo sapiens cDNA: FLJ23203 fis, clone ADKA02487 AK026856 216794_at AK026856 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026856.1 /DEF=Homo sapiens cDNA: FLJ23203 fis, clone ADKA02487. /FEA=mRNA /DB_XREF=gi:10439812 /UG=Hs.306889 Homo sapiens cDNA: FLJ23203 fis, clone ADKA02487 AK026856 216795_at AK026847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026847.1 /DEF=Homo sapiens cDNA: FLJ23194 fis, clone REC00490. /FEA=mRNA /DB_XREF=gi:10439802 /UG=Hs.306887 Homo sapiens cDNA: FLJ23194 fis, clone REC00490 AK026847 216796_s_at AK026847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026847.1 /DEF=Homo sapiens cDNA: FLJ23194 fis, clone REC00490. /FEA=mRNA /DB_XREF=gi:10439802 /UG=Hs.306887 Homo sapiens cDNA: FLJ23194 fis, clone REC00490 AK026847 216797_at AK026847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026847.1 /DEF=Homo sapiens cDNA: FLJ23194 fis, clone REC00490. /FEA=mRNA /DB_XREF=gi:10439802 /UG=Hs.306887 Homo sapiens cDNA: FLJ23194 fis, clone REC00490 AK026847 216798_at AK027172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027172.1 /DEF=Homo sapiens cDNA: FLJ23519 fis, clone LNG04908. /FEA=mRNA /DB_XREF=gi:10440237 /UG=Hs.306907 Homo sapiens cDNA: FLJ23519 fis, clone LNG04908 AK027172 uncharacterized protein FLJ23519 /// ribonuclease/angiogenin inhibitor 1 FLJ23519 /// RNH1 6050 /// 84200 NM_002939 /// NM_203383 /// NM_203384 /// NM_203385 /// NM_203386 /// NM_203387 /// NM_203388 /// NM_203389 0006402 // mRNA catabolic process // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0032311 // angiogenin-PRI complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008428 // ribonuclease inhibitor activity // inferred from direct assay 216799_at AL442084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL442084.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547G044 (from clone DKFZp547G044). /FEA=mRNA /DB_XREF=gi:10241763 /UG=Hs.306924 Homo sapiens mRNA; cDNA DKFZp547G044 (from clone DKFZp547G044) AL442084 216800_at AK027069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027069.1 /DEF=Homo sapiens cDNA: FLJ23416 fis, clone HEP20790. /FEA=mRNA /DB_XREF=gi:10440096 /UG=Hs.306900 Homo sapiens cDNA: FLJ23416 fis, clone HEP20790 AK027069 216801_at AK026910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026910.1 /DEF=Homo sapiens cDNA: FLJ23257 fis, clone COL05579. /FEA=mRNA /DB_XREF=gi:10439880 /UG=Hs.306896 Homo sapiens cDNA: FLJ23257 fis, clone COL05579 AK026910 216802_at AL442084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL442084.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547G044 (from clone DKFZp547G044). /FEA=mRNA /DB_XREF=gi:10241763 /UG=Hs.306924 Homo sapiens mRNA; cDNA DKFZp547G044 (from clone DKFZp547G044) AL442084 216803_at AK027217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027217.1 /DEF=Homo sapiens cDNA: FLJ23564 fis, clone LNG10773. /FEA=mRNA /DB_XREF=gi:10440296 /UG=Hs.306913 Homo sapiens cDNA: FLJ23564 fis, clone LNG10773 AK027217 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 216804_s_at AK027217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027217.1 /DEF=Homo sapiens cDNA: FLJ23564 fis, clone LNG10773. /FEA=mRNA /DB_XREF=gi:10440296 /UG=Hs.306913 Homo sapiens cDNA: FLJ23564 fis, clone LNG10773 AK027217 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 216805_at AK027254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027254.1 /DEF=Homo sapiens cDNA: FLJ23601 fis, clone LNG15501. /FEA=mRNA /DB_XREF=gi:10440343 /UG=Hs.306918 Homo sapiens cDNA: FLJ23601 fis, clone LNG15501 AK027254 216806_at AL136306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136306 /DEF=Human DNA sequence from clone RP3-334F4 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a LAMR1 (laminin receptor 1, ribosomal protein SA) pseudogene and an RPL10 (ribosomal protein L10) pseudogene /FEA=CDS_1 /DB_XREF=gi:10045289 /UG=Hs.307102 Human DNA sequence from clone RP3-334F4 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a LAMR1 (laminin receptor 1, ribosomal protein SA) pseudogene and an RPL10 (ribosomal protein L10) pseudogene AL136306 RP3-334F4.1 216807_at AB051538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051538.1 /DEF=Homo sapiens mRNA for KIAA1751 protein, partial cds. /FEA=mRNA /GEN=KIAA1751 /PROD=KIAA1751 protein /DB_XREF=gi:12698046 /UG=Hs.307002 Homo sapiens mRNA for KIAA1751 protein, partial cds AB051538 KIAA1751 KIAA1751 85452 NM_001003808 /// NM_001080484 /// XM_003119800 /// XM_005244811 /// XM_006710997 /// XM_006710998 216808_at AL354915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL354915 /DEF=Human DNA sequence from clone RP11-392A19 on chromosome 13. Contains ESTs, STSs and GSSs. Contains a novel pseudogene and a KRT18 (keratin type 1 cytoskeletal 18, cytokeratin 18) pseudogene /FEA=CDS_2 /DB_XREF=gi:10129445 /UG=Hs.307121 Human DNA sequence from clone RP11-392A19 on chromosome 13. Contains ESTs, STSs and GSSs. Contains a novel pseudogene and a KRT18 (keratin type 1 cytoskeletal 18, cytokeratin 18) pseudogene AL354915 microRNA 622 MIR622 693207 NR_030754 216809_at Z22780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22780.1 /DEF=H.sapiens cylicin mRNA. /FEA=mRNA /PROD=cylicin /DB_XREF=gi:396104 /UG=Hs.307358 cylicin, basic protein of sperm head cytoskeleton 1 Z22780 cylicin, basic protein of sperm head cytoskeleton 1 CYLC1 1538 NM_001271680 /// NM_021118 /// XM_005262086 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0033150 // cytoskeletal calyx // inferred from electronic annotation /// 0043159 // acrosomal matrix // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation 216810_at AJ406939 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ406939.1 /DEF=Homo sapiens mRNA for keratin associated protein 4.7 (KRTAP4.7 gene). /FEA=mRNA /GEN=KRTAP4.7 /PROD=keratin associated protein 4.7 /DB_XREF=gi:12655451 /UG=Hs.307020 Homo sapiens mRNA for keratin associated protein 4.7 (KRTAP4.7 gene) AJ406939 keratin associated protein 4-7 KRTAP4-7 100132476 NM_033061 0007568 // aging // inferred from direct assay /// 0042633 // hair cycle // inferred from direct assay 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 216811_at AF308291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF308291.1 /DEF=Homo sapiens serologically defined breast cancer antigen NY-BR-46 mRNA, partial cds. /FEA=mRNA /PROD=serologically defined breast cancer antigenNY-BR-46 /DB_XREF=gi:12060833 /UG=Hs.307075 Homo sapiens serologically defined breast cancer antigen NY-BR-46 mRNA, partial cds AF308291 216812_at AF308291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF308291.1 /DEF=Homo sapiens serologically defined breast cancer antigen NY-BR-46 mRNA, partial cds. /FEA=mRNA /PROD=serologically defined breast cancer antigenNY-BR-46 /DB_XREF=gi:12060833 /UG=Hs.307075 Homo sapiens serologically defined breast cancer antigen NY-BR-46 mRNA, partial cds AF308291 216813_at AL512728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512728.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547P082 (from clone DKFZp547P082). /FEA=mRNA /GEN=DKFZp547P082 /PROD=hypothetical protein /DB_XREF=gi:12224871 /UG=Hs.307068 Homo sapiens mRNA; cDNA DKFZp547P082 (from clone DKFZp547P082) AL512728 216814_at AL353587 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353587 /DEF=Human DNA sequence from clone RP13-178D16 on chromosome X Contains a pseudogene similar to Actin, a novel pseudogene, ESTs, STSs and GSSs /FEA=CDS_1 /DB_XREF=gi:9801355 /UG=Hs.307114 Human DNA sequence from clone RP13-178D16 on chromosome X Contains a pseudogene similar to Actin, a novel pseudogene, ESTs, STSs and GSSs AL353587 ACTR3 pseudogene 2 /// ACTR3P2 /// ACTR3P2 216815_at AL136306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136306 /DEF=Human DNA sequence from clone RP3-334F4 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a LAMR1 (laminin receptor 1, ribosomal protein SA) pseudogene and an RPL10 (ribosomal protein L10) pseudogene /FEA=CDS_2 /DB_XREF=gi:10045289 /UG=Hs.307103 Human DNA sequence from clone RP3-334F4 on chromosome 6 Contains ESTs, STSs and GSSs. Contains a LAMR1 (laminin receptor 1, ribosomal protein SA) pseudogene and an RPL10 (ribosomal protein L10) pseudogene AL136306 RP3-334F4.2 216816_at AL050335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050335 /DEF=Human DNA sequence from clone RP1-190J20 on chromosome 6p22.3-24.1. Contains ESTs, STSs and GSSs. Contains a putative novel gene and an RPL6 (60S ribososmal protein L6) pseudogene /FEA=CDS /DB_XREF=gi:10120307 /UG=Hs.307107 Human DNA sequence from clone RP1-190J20 on chromosome 6p22.3-24.1. Contains ESTs, STSs and GSSs. Contains a putative novel gene and an RPL6 (60S ribososmal protein L6) pseudogene AL050335 RP1-190J20.2 216817_s_at AJ302604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ302604 /DEF=Homo sapiens 6M1-16*01 gene for olfactory receptor, cell line LG2 /FEA=CDS /DB_XREF=gi:12054432 /UG=Hs.307112 Homo sapiens 6M1-16*01 gene for olfactory receptor, cell line LG2 AJ302604 olfactory receptor, family 2, subfamily H, member 1 OR2H1 26716 NM_030883 /// XM_005249008 /// XM_005249009 /// XM_005272791 /// XM_005272792 /// XM_005274845 /// XM_005274846 /// XM_005274937 /// XM_005274938 /// XM_005275091 /// XM_005275092 /// XM_005275233 /// XM_005275234 /// XM_005275367 /// XM_005275368 /// XM_005275527 /// XM_005275528 /// XM_006725032 /// XM_006725033 /// XM_006725809 /// XM_006725810 /// XM_006725990 /// XM_006725991 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 216818_s_at AJ302559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ302559 /DEF=Homo sapiens 6M1-4P*01 pseudogene, cell line LG2 /FEA=CDS /DB_XREF=gi:12054348 /UG=Hs.307110 Homo sapiens 6M1-4P*01 pseudogene, cell line LG2 AJ302559 olfactory receptor, family 2, subfamily J, member 2 OR2J2 26707 NM_030905 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 216819_at AL359553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359553 /DEF=Human DNA sequence from clone RP5-871G17 on chromosome 1. Contains ESTs, STSs and GSSs. Contains the HAO2 gene for hydroxyacid oxidase 2 (long chain), the HSD3B2 gene for hydroxy-delta-5-steroid dehydrogenase (3 beta-and steroid delta-isomerase 2)... /FEA=CDS_2 /DB_XREF=gi:9944183 /UG=Hs.307109 Human DNA sequence from clone RP5-871G17 on chromosome 1. Contains ESTs, STSs and GSSs. Contains the HAO2 gene for hydroxyacid oxidase 2 (long chain), the HSD3B2 gene for hydroxy-delta-5-steroid dehydrogenase (3 beta-and steroid delta-isomerase 2), two GA AL359553 hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 1 /// HSD3BP1 /// HSD3BP1 216820_at AL390857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390857 /DEF=Human DNA sequence from clone RP11-51N22 on chromosome 13 Contains ESTs, STSs and GSSs. Contains an HNRPA1 (heterogeneous nuclear ribonucleoprotein A1) pseudogene /FEA=CDS /DB_XREF=gi:10334471 /UG=Hs.307134 Human DNA sequence from clone RP11-51N22 on chromosome 13 Contains ESTs, STSs and GSSs. Contains an HNRPA1 (heterogeneous nuclear ribonucleoprotein A1) pseudogene AL390857 heterogeneous nuclear ribonucleoprotein A1 pseudogene 31 /// HNRNPA1P31 /// HNRNPA1P31 216821_at AL137067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137067 /DEF=Human DNA sequence from clone RP11-13B9 on chromosome 9q22.32-31.3. Contains a gene for a novel protein similar to a glycosyltransferase, a gene for a novel protein similar to the beta subunit of the transport protein SEC61 and a novel gene for a ... /FEA=CDS_1 /DB_XREF=gi:8452467 /UG=Hs.307126 Human DNA sequence from clone RP11-13B9 on chromosome 9q22.32-31.3. Contains a gene for a novel protein similar to a glycosyltransferase, a gene for a novel protein similar to the beta subunit of the transport protein SEC61 and a novel gene for a protein AL137067 keratin 8 pseudogene 11 /// KRT8P11 /// KRT8P11 216822_x_at AL359763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL359763 /DEF=Human DNA sequence from clone RP11-169O17 on chromosome 13 Contains ESTs, GSSs, STSs and four CpG islands. Contains a novel protein similar to cytochrome c, part of a novel gene similar to TPTE encoding a transmembrane phosphatase with tensin homo... /FEA=CDS_1 /DB_XREF=gi:10045472 /UG=Hs.307122 Human DNA sequence from clone RP11-169O17 on chromosome 13 Contains ESTs, GSSs, STSs and four CpG islands. Contains a novel protein similar to cytochrome c, part of a novel gene similar to TPTE encoding a transmembrane phosphatase with tensin homology and AL359763 cytochrome c, somatic pseudogene 33 /// CYCSP33 /// CYCSP33 216823_at AL356115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL356115 /DEF=Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands /FEA=CDS_1 /DB_XREF=gi:9795038 /UG=Hs.307132 Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands AL356115 ribosomal protein S3A /// small nucleolar RNA, C/D box 73A RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216824_at AL157375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157375 /DEF=Human DNA sequence from clone RP1-133P16 on chromosome 6 Contains the ARF1 (ADP-ribosylation factor 1) gene, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:9581575 /UG=Hs.307130 Human DNA sequence from clone RP1-133P16 on chromosome 6 Contains the ARF1 (ADP-ribosylation factor 1) gene, ESTs, STSs and GSSs AL157375 /// ADP-ribosylation factor 1 pseudogene 1 ARF1P1 /// ARF1P1 216825_s_at AL139289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139289 /DEF=Human DNA sequence from clone RP1-92O14 on chromosome 1p33-34.2 Contains part of the TIE (tyrosine kinase with immunoglobulinand epidermal growth factor homology domains) gene, the gene for MPL (myeloproliferative leukemia virus oncogene), a gene... /FEA=mRNA_1 /DB_XREF=gi:7529223 /UG=Hs.307129 Human DNA sequence from clone RP1-92O14 on chromosome 1p33-34.2 Contains part of the TIE (tyrosine kinase with immunoglobulinand epidermal growth factor homology domains) gene, the gene for MPL (myeloproliferative leukemia virus oncogene), a gene similar AL139289 MPL proto-oncogene, thrombopoietin receptor MPL 4352 NM_005373 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032642 // regulation of chemokine production // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation 216826_at AL356954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL356954 /DEF=Human DNA sequence from clone RP11-520F24 on chromosome 13 Contains ESTs, STSs and GSSs. Contains an HNRPA1 (heterogenous nuclear ribonucleoprotein A1) pseudogene and an RNA polymerase II elongation factor ELL2 pseudogene /FEA=CDS /DB_XREF=gi:12225422 /UG=Hs.307142 Human DNA sequence from clone RP11-520F24 on chromosome 13 Contains ESTs, STSs and GSSs. Contains an HNRPA1 (heterogenous nuclear ribonucleoprotein A1) pseudogene and an RNA polymerase II elongation factor ELL2 pseudogene AL356954 elongation factor, RNA polymerase II, 2 pseudogene 3 /// ELL2P3 /// ELL2P3 216827_at AL355379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL355379 /DEF=Human DNA sequence from clone RP3-508D13 on chromosome 6 Contains a heat shock protein DNAJ pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9944158 /UG=Hs.307138 Human DNA sequence from clone RP3-508D13 on chromosome 6 Contains a heat shock protein DNAJ pseudogene, ESTs, STSs and GSSs AL355379 RP3-508D13.1 216828_at AL441988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL441988 /DEF=Human DNA sequence from clone RP11-348I14 on chromosome 20 Contains ESTs, STSs, GSSs and two CpG islands. Contains a novel gene, a novel gene similar to FRG1 encoding FSHD (fascioscapulohumeral muscular dystrophy) region gene 1 and part of a novel... /FEA=CDS_1 /DB_XREF=gi:11990063 /UG=Hs.307135 Human DNA sequence from clone RP11-348I14 on chromosome 20 Contains ESTs, STSs, GSSs and two CpG islands. Contains a novel gene, a novel gene similar to FRG1 encoding FSHD (fascioscapulohumeral muscular dystrophy) region gene 1 and part of a novel gene si AL441988 uncharacterized LOC100505874 /// myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 pseudogene 1 LOC100505874 /// MLLT10P1 140678 /// 100505874 NR_045115 /// XR_110948 /// XR_430603 /// XR_430604 216829_at X72475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X72475.1 /DEF=H.sapiens mRNA for rearranged Ig kappa light chain variable region (I.114). /FEA=mRNA /PROD=Ig kappa light chain (VJC) /DB_XREF=gi:441418 /UG=Hs.307183 H.sapiens mRNA for rearranged Ig kappa light chain variable region (I.114) X72475 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216830_at AC004460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004460 /DEF=Homo sapiens PAC clone RP5-1086D14 /FEA=CDS /DB_XREF=gi:2981263 /UG=Hs.307352 Homo sapiens PAC clone RP5-1086D14 AC004460 HECT and RLD domain containing E3 ubiquitin protein ligase 2 /// hect domain and RLD 2 pseudogene 10 /// uncharacterized LOC101929047 /// uncharacterized LOC101929832 HERC2 /// HERC2P10 /// LOC101929047 /// LOC101929832 8924 /// 390561 /// 101929047 /// 101929832 NM_004667 /// NR_072991 /// XM_005268276 /// XM_005268277 /// XM_006720726 /// XM_006720727 /// XR_245838 /// XR_245839 /// XR_254221 /// XR_254225 /// XR_429494 /// XR_429495 /// XR_430870 /// XR_430871 /// XR_430872 /// XR_430873 /// XR_431082 0006281 // DNA repair // inferred from direct assay /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043087 // regulation of GTPase activity // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from direct assay 216831_s_at AF018283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF018283.1 /DEF=Homo sapiens putative transcription factor (MTG8) mRNA, alternatively spliced, partial cds. /FEA=mRNA /GEN=MTG8 /DB_XREF=gi:2582202 /UG=Hs.307345 Homo sapiens putative transcription factor (MTG8) mRNA, alternatively spliced, partial cds AF018283 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) RUNX1T1 862 NM_001198625 /// NM_001198626 /// NM_001198627 /// NM_001198628 /// NM_001198629 /// NM_001198630 /// NM_001198631 /// NM_001198632 /// NM_001198633 /// NM_001198634 /// NM_001198679 /// NM_004349 /// NM_175634 /// NM_175635 /// NM_175636 /// XM_006716676 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0051101 // regulation of DNA binding // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 216832_at AF018283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF018283.1 /DEF=Homo sapiens putative transcription factor (MTG8) mRNA, alternatively spliced, partial cds. /FEA=mRNA /GEN=MTG8 /DB_XREF=gi:2582202 /UG=Hs.307345 Homo sapiens putative transcription factor (MTG8) mRNA, alternatively spliced, partial cds AF018283 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) RUNX1T1 862 NM_001198625 /// NM_001198626 /// NM_001198627 /// NM_001198628 /// NM_001198629 /// NM_001198630 /// NM_001198631 /// NM_001198632 /// NM_001198633 /// NM_001198634 /// NM_001198679 /// NM_004349 /// NM_175634 /// NM_175635 /// NM_175636 /// XM_006716676 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0051101 // regulation of DNA binding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216833_x_at U05255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U05255.1 /DEF=Human glycophorin HeP2 mRNA, partial cds. /FEA=mRNA /PROD=glycophorin HeP2 /DB_XREF=gi:454085 /UG=Hs.307185 Human glycophorin HeP2 mRNA, partial cds U05255 glycophorin B (MNS blood group) GYPB 2994 NM_002100 /// XM_005262968 /// XM_005262969 /// XM_005262970 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 216834_at S59049 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S59049.1 /DEF=BL34=B cell activation gene human, mRNA, 1398 nt. /FEA=mRNA /GEN=BL34 /DB_XREF=gi:299704 /UG=Hs.75256 regulator of G-protein signalling 1 S59049 regulator of G-protein signaling 1 RGS1 5996 NM_002922 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 216835_s_at AF035299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF035299.1 /DEF=Homo sapiens clone 23863 mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:2661055 /UG=Hs.103854 docking protein 1, 62kD (downstream of tyrosine kinase 1) AF035299 docking protein 1, 62kDa (downstream of tyrosine kinase 1) DOK1 1796 NM_001197260 /// NM_001381 /// XM_005264180 /// XM_006711959 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 216836_s_at X03363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X03363.1 /DEF=Human c-erb-B-2 mRNA. /FEA=mRNA /DB_XREF=gi:31197 /UG=Hs.323910 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuroglioblastoma derived oncogene homolog) X03363 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 ERBB2 2064 NM_001005862 /// NM_001289936 /// NM_001289937 /// NM_001289938 /// NM_004448 /// NR_110535 /// XM_005257140 /// XM_006721765 /// XM_006721766 /// XM_006721767 /// XM_006721768 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from genetic interaction /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030879 // mammary gland development // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0032886 // regulation of microtubule-based process // inferred from direct assay /// 0033088 // negative regulation of immature T cell proliferation in thymus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from direct assay /// 0042552 // myelination // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045765 // regulation of angiogenesis // non-traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from mutant phenotype /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043235 // receptor complex // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001042 // RNA polymerase I core binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from genetic interaction /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043125 // ErbB-3 class receptor binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // non-traceable author statement 216837_at L36644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L36644.1 /DEF=Homo sapiens receptor protein-tyrosine kinase (HEK7) mRNA, 3 end. /FEA=mRNA /GEN=HEK7 /PROD=receptor protein-tyrosine kinase /DB_XREF=gi:551611 /UG=Hs.31092 EphA5 L36644 EPH receptor A5 EPHA5 2044 NM_001281765 /// NM_001281766 /// NM_001281767 /// NM_004439 /// NM_182472 /// XM_005265653 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032793 // positive regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from expression pattern /// 0051964 // negative regulation of synapse assembly // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from sequence or structural similarity /// 0005004 // GPI-linked ephrin receptor activity // inferred from sequence or structural similarity /// 0005005 // transmembrane-ephrin receptor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 216838_at AK023798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023798.1 /DEF=Homo sapiens cDNA FLJ13736 fis, clone PLACE3000156. /FEA=mRNA /DB_XREF=gi:10435842 /UG=Hs.31532 Homo sapiens mRNA; cDNA DKFZp434F172 (from clone DKFZp434F172) AK023798 long intergenic non-protein coding RNA 1278 LINC01278 92249 NR_015353 216839_at AK026829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026829.1 /DEF=Homo sapiens cDNA: FLJ23176 fis, clone LNG10452. /FEA=mRNA /DB_XREF=gi:10439775 /UG=Hs.323511 Homo sapiens cDNA: FLJ23176 fis, clone LNG10452 AK026829 laminin, alpha 2 LAMA2 3908 NM_000426 /// NM_001079823 /// XM_005266981 /// XM_005266982 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement 216840_s_at AK026829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026829.1 /DEF=Homo sapiens cDNA: FLJ23176 fis, clone LNG10452. /FEA=mRNA /DB_XREF=gi:10439775 /UG=Hs.323511 Homo sapiens cDNA: FLJ23176 fis, clone LNG10452 AK026829 laminin, alpha 2 LAMA2 3908 NM_000426 /// NM_001079823 /// XM_005266981 /// XM_005266982 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216841_s_at X15132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X15132.1 /DEF=Human mRNA for manganese containing superoxide dismutase (EC 1.15.1.1). /FEA=mRNA /DB_XREF=gi:34794 /UG=Hs.318885 superoxide dismutase 2, mitochondrial X15132 uncharacterized LOC100129518 /// superoxide dismutase 2, mitochondrial LOC100129518 /// SOD2 6648 /// 100129518 NM_000636 /// NM_001024465 /// NM_001024466 /// NR_037166 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from mutant phenotype /// 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001315 // age-dependent response to reactive oxygen species // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0003032 // detection of oxygen // inferred from electronic annotation /// 0003069 // vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034021 // response to silicon dioxide // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048773 // erythrophore differentiation // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0030145 // manganese ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216842_x_at U38460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U38460 /DEF=Human RNA binding motif (RBM) gene, partial cds /FEA=CDS /DB_XREF=gi:1061399 /UG=Hs.326802 Human RNA binding motif (RBM) gene, partial cds U38460 /// RNA binding motif protein, Y-linked, family 2, member T pseudogene /// AC007967.3 /// RBMY2TP /// RBMY2TP 216843_x_at U38964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U38964 /DEF=Human PMS2 related (hPMSR2) gene, complete cds /FEA=CDS /DB_XREF=gi:1055353 /UG=Hs.323954 postmeiotic segregation increased 2-like 8 U38964 postmeiotic segregation increased 2 pseudogene 1 PMS2P1 5379 NM_005394 /// NR_003613 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 216844_at BC004857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004857.1 /DEF=Homo sapiens, clone IMAGE:3690478, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3690478) /DB_XREF=gi:13436058 /UG=Hs.326447 Homo sapiens, clone IMAGE:3690478, mRNA, partial cds BC004857 zinc finger CCCH-type containing 7B ZC3H7B 23264 NM_017590 0016032 // viral process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216845_x_at U80756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80756.1 /DEF=Homo sapiens CAGL114 mRNA, partial cds. /FEA=mRNA /GEN=CAGL114 /DB_XREF=gi:2565081 /UG=Hs.326533 trinucleotide repeat containing 21 U80756 lysine (K)-specific methyltransferase 2D KMT2D 8085 NM_003482 /// XM_005269162 /// XM_006719614 /// XM_006719615 /// XM_006719616 0001555 // oocyte growth // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0035097 // histone methyltransferase complex // inferred from physical interaction 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216846_at AF234254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF234254.1 /DEF=Homo sapiens clone KM35 immunoglobulin light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin light chain variable region /DB_XREF=gi:13171335 /UG=Hs.326780 Homo sapiens clone KM35 immunoglobulin light chain variable region mRNA, partial cds AF234254 immunoglobulin lambda light chain-like CYAT1 100290481 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216847_at AB051447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051447.1 /DEF=Homo sapiens mRNA for KIAA1660 protein, partial cds. /FEA=mRNA /GEN=KIAA1660 /PROD=KIAA1660 protein /DB_XREF=gi:13359192 /UG=Hs.326757 Homo sapiens mRNA for KIAA1660 protein, partial cds AB051447 216848_at AB051447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051447.1 /DEF=Homo sapiens mRNA for KIAA1660 protein, partial cds. /FEA=mRNA /GEN=KIAA1660 /PROD=KIAA1660 protein /DB_XREF=gi:13359192 /UG=Hs.326757 Homo sapiens mRNA for KIAA1660 protein, partial cds AB051447 216849_at AL080233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080233.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L111 (from clone DKFZp586L111). /FEA=mRNA /DB_XREF=gi:5262726 /UG=Hs.326580 Homo sapiens mRNA; cDNA DKFZp586L111 (from clone DKFZp586L111) AL080233 AC007389.3 216850_at AF319523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF319523.1 /DEF=Homo sapiens RT-LI mRNA, complete sequence. /FEA=mRNA /PROD=RT-LI /DB_XREF=gi:13310144 /UG=Hs.326775 Homo sapiens RT-LI mRNA, complete sequence AF319523 imprinted in Prader-Willi syndrome (non-protein coding) /// uncharacterized LOC101930404 /// Prader Willi/Angelman region RNA, SNRPN neighbor /// small nucleolar RNA, C/D box 107 /// small nucleolar RNA, C/D box 115-13 /// small nucleolar RNA, C/D box 115-26 /// small nucleolar RNA, C/D box 115-7 /// small nucleolar RNA, C/D box 116-22 /// small nucleolar RNA, C/D box 116-28 /// small nucleolar RNA, C/D box 116-4 /// small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame IPW /// LOC101930404 /// PWARSN /// SNORD107 /// SNORD115-13 /// SNORD115-26 /// SNORD115-7 /// SNORD116-22 /// SNORD116-28 /// SNORD116-4 /// SNRPN /// SNURF 3653 /// 6638 /// 8926 /// 91380 /// 347746 /// 100033416 /// 100033433 /// 100033444 /// 100033450 /// 100033802 /// 100033820 /// 101930404 NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 /// NR_001293 /// NR_003299 /// NR_003305 /// NR_003319 /// NR_003336 /// NR_003343 /// NR_003361 /// NR_022011 /// NR_023915 /// XR_250593 /// XR_426491 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 216851_at AF234254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF234254.1 /DEF=Homo sapiens clone KM35 immunoglobulin light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin light chain variable region /DB_XREF=gi:13171335 /UG=Hs.326780 Homo sapiens clone KM35 immunoglobulin light chain variable region mRNA, partial cds AF234254 216852_x_at AF234255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF234255.1 /DEF=Homo sapiens clone KM36 immunoglobulin light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin light chain variable region /DB_XREF=gi:13171337 /UG=Hs.326779 Homo sapiens clone KM36 immunoglobulin light chain variable region mRNA, partial cds AF234255 immunoglobulin lambda joining 3 IGLJ3 28831 216853_x_at AF234255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF234255.1 /DEF=Homo sapiens clone KM36 immunoglobulin light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin light chain variable region /DB_XREF=gi:13171337 /UG=Hs.326779 Homo sapiens clone KM36 immunoglobulin light chain variable region mRNA, partial cds AF234255 immunoglobulin lambda joining 3 /// immunoglobulin lambda variable 3-19 /// IGLJ3 /// IGLV3-19 /// IGLV3-19 28831 0005515 // protein binding // inferred from electronic annotation 216854_at AF028333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF028333.1 /DEF=Homo sapiens growthdifferentiation factor-11 (GDF11) mRNA, partial cds. /FEA=mRNA /GEN=GDF11 /PROD=growthdifferentiation factor-11 /DB_XREF=gi:6649913 /UG=Hs.34941 growth differentiation factor 11 AF028333 growth differentiation factor 11 GDF11 10220 NM_005811 /// XM_006719193 /// XM_006719194 0001501 // skeletal system development // traceable author statement /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021512 // spinal cord anterior/posterior patterning // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 216855_s_at D13413 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D13413.1 /DEF=Human mRNA for tumor-associated 120 kDa nuclear protein p120, partial cds(carboxyl terminus). /FEA=mRNA /PROD=p120 /DB_XREF=gi:433414 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) D13413 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216856_s_at AF264787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF264787.1 /DEF=Homo sapiens BCMS-upstream neighbor (BCMSUN) mRNA, partial sequence. /FEA=mRNA /DB_XREF=gi:11141510 /UG=Hs.43628 deleted in lymphocytic leukemia, 2 AF264787 deleted in lymphocytic leukemia 2-like DLEU2L 216857_at L48728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L48728 /DEF=Homo sapiens T cell receptor beta (TCRBV10S1) gene, complete cds /FEA=mRNA_1 /DB_XREF=gi:1054550 /UG=Hs.37163 Homo sapiens T cell receptor beta (TCRBV10S1) gene, complete cds L48728 interleukin 23, alpha subunit p19 /// Homo sapiens mRNA for T cell receptor beta variable 21, partial cds, clone: SEB 169. /// T cell receptor beta variable 21-1 (pseudogene) /// IL23A /// TCRBV10S1P /// TRBV21-1 /// TRBV21-1 51561 NM_016584 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0045519 // interleukin-23 receptor binding // inferred from direct assay 216858_x_at AL080112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080112.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H0722 (from clone DKFZp586H0722). /FEA=mRNA /DB_XREF=gi:5262539 /UG=Hs.332731 Homo sapiens mRNA; cDNA DKFZp586H0722 (from clone DKFZp586H0722) AL080112 216859_x_at AL080112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080112.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H0722 (from clone DKFZp586H0722). /FEA=mRNA /DB_XREF=gi:5262539 /UG=Hs.332731 Homo sapiens mRNA; cDNA DKFZp586H0722 (from clone DKFZp586H0722) AL080112 216860_s_at AF028333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF028333.1 /DEF=Homo sapiens growthdifferentiation factor-11 (GDF11) mRNA, partial cds. /FEA=mRNA /GEN=GDF11 /PROD=growthdifferentiation factor-11 /DB_XREF=gi:6649913 /UG=Hs.34941 growth differentiation factor 11 AF028333 growth differentiation factor 11 GDF11 10220 NM_005811 /// XM_006719193 /// XM_006719194 0001501 // skeletal system development // traceable author statement /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021512 // spinal cord anterior/posterior patterning // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 216861_at U05589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U05589.1 /DEF=Human ribosomal protein S1 homolog mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:497001 /UG=Hs.371 ribosomal protein S1-like U05589 0006412 // translation // inferred from electronic annotation 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 216862_s_at Z24459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z24459 /DEF=H.sapiens MTCP1 gene, exons 2A to 7 (and joined mRNA) /FEA=mRNA_4 /DB_XREF=gi:2252491 /UG=Hs.3548 mature T-cell proliferation 1 Z24459 C-x(9)-C motif containing 4 CMC4 100272147 NM_001018024 0008283 // cell proliferation // traceable author statement 0005739 // mitochondrion // inferred from direct assay 216863_s_at AC004542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004542 /DEF=Homo sapiens PAC clone RP3-430N8 from 22q12.1-qter /FEA=CDS /DB_XREF=gi:3041846 /UG=Hs.35276 KIAA0852 protein AC004542 MORC family CW-type zinc finger 2 MORC2 22880 NM_014941 /// XM_005261391 /// XM_005261392 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216864_at U05589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U05589.1 /DEF=Human ribosomal protein S1 homolog mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:497001 /UG=Hs.371 ribosomal protein S1-like U05589 0006412 // translation // inferred from electronic annotation 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 216865_at M64108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M64108.1 /DEF=Human udulin 1 mRNA, 3 end. /FEA=mRNA /PROD=undulin 1 /DB_XREF=gi:340081 /UG=Hs.36131 collagen, type XIV, alpha 1 (undulin) M64108 collagen, type XIV, alpha 1 COL14A1 7373 NM_021110 /// XM_005251059 /// XM_006716651 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0061050 // regulation of cell growth involved in cardiac muscle cell development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // non-traceable author statement /// 0005596 // collagen type XIV trimer // non-traceable author statement /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 216866_s_at M64108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M64108.1 /DEF=Human udulin 1 mRNA, 3 end. /FEA=mRNA /PROD=undulin 1 /DB_XREF=gi:340081 /UG=Hs.36131 collagen, type XIV, alpha 1 (undulin) M64108 collagen, type XIV, alpha 1 COL14A1 7373 NM_021110 /// XM_005251059 /// XM_006716651 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0061050 // regulation of cell growth involved in cardiac muscle cell development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // non-traceable author statement /// 0005596 // collagen type XIV trimer // non-traceable author statement /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 216867_s_at X03795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X03795.1 /DEF=Human mRNA for platelet derived growth factor A-chain (PDGF-A). /FEA=mRNA /DB_XREF=gi:35365 /UG=Hs.37040 platelet-derived growth factor alpha polypeptide X03795 platelet-derived growth factor alpha polypeptide PDGFA 5154 NM_002607 /// NM_033023 /// XM_005249770 /// XM_006715733 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009790 // embryo development // traceable author statement /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0030031 // cell projection assembly // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043588 // skin development // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048839 // inner ear development // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060683 // regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072124 // regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 2000278 // regulation of DNA biosynthetic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005902 // microvillus // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 216868_s_at D13413 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D13413.1 /DEF=Human mRNA for tumor-associated 120 kDa nuclear protein p120, partial cds(carboxyl terminus). /FEA=mRNA /PROD=p120 /DB_XREF=gi:433414 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) D13413 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 216869_at U40372 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U40372.1 /DEF=Human 3,5 cyclic nucleotide phosphodiesterase (HSPDE1C3A) mRNA, partial cds. /FEA=mRNA /PROD=PDE1C3 /DB_XREF=gi:1151112 /UG=Hs.41718 phosphodiesterase 1C, calmodulin-dependent (70kD) U40372 phosphodiesterase 1C, calmodulin-dependent 70kDa PDE1C 5137 NM_001191056 /// NM_001191057 /// NM_001191058 /// NM_001191059 /// NM_005020 /// XM_005249768 /// XM_005249769 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004117 // calmodulin-dependent cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216870_x_at AF264787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF264787.1 /DEF=Homo sapiens BCMS-upstream neighbor (BCMSUN) mRNA, partial sequence. /FEA=mRNA /DB_XREF=gi:11141510 /UG=Hs.43628 deleted in lymphocytic leukemia, 2 AF264787 deleted in lymphocytic leukemia 2 (non-protein coding) DLEU2 8847 NR_002612 216871_at AF161412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161412.1 /DEF=Homo sapiens HSPC294 mRNA, partial cds. /FEA=mRNA /PROD=HSPC294 /DB_XREF=gi:6841237 /UG=Hs.4014 KIAA0946 protein; Huntingtin interacting protein H AF161412 216872_at X91103 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X91103.1 /DEF=H.sapiens mRNA for Hr44 protein. /FEA=mRNA /GEN=hr44 /DB_XREF=gi:1054775 /UG=Hs.102131 Hr44 antigen X91103 0016021 // integral component of membrane // non-traceable author statement 216873_s_at AL137537 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137537.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0219 (from clone DKFZp434M0219); partial cds. /FEA=mRNA /GEN=DKFZp434M0219 /PROD=hypothetical protein /DB_XREF=gi:6808214 /UG=Hs.43577 ATPase, Class I, type 8B, member 2 AL137537 ATPase, aminophospholipid transporter, class I, type 8B, member 2 ATP8B2 57198 NM_001005855 /// NM_020452 /// XM_005245355 /// XM_005245356 /// XR_241091 0006200 // ATP catabolic process // inferred from reviewed computational analysis /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from reviewed computational analysis 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from reviewed computational analysis /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216874_at U80770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80770.1 /DEF=Human EST clone 251800 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2921608 /UG=Hs.42192 Human EST clone 251800 mariner transposon Hsmar1 sequence U80770 uncharacterized LOC100505498 LOC100505498 100505498 XM_005263847 /// XM_005275934 /// XM_005276217 216875_x_at X83412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83412.1 /DEF=H.sapiens B1 mRNA for mucin. /FEA=mRNA /GEN=B1 /PROD=mucin /DB_XREF=gi:853955 /UG=Hs.100015 B1 for mucin X83412 B1 for mucin HAB1 55547 216876_s_at Z58820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z58820.1 /DEF=H.sapiens CTLA8 mRNA. /FEA=mRNA /GEN=CTLA8 /PROD=hIL-17 /DB_XREF=gi:1469244 /UG=Hs.41724 interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) Z58820 interleukin 17A IL17A 3605 NM_002190 0006486 // protein glycosylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008219 // cell death // traceable author statement /// 0032747 // positive regulation of interleukin-23 production // inferred from direct assay /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0072537 // fibroblast activation // inferred from direct assay /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation 216877_at U80770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80770.1 /DEF=Human EST clone 251800 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2921608 /UG=Hs.42192 Human EST clone 251800 mariner transposon Hsmar1 sequence U80770 uncharacterized LOC100505498 LOC100505498 100505498 XM_005263847 /// XM_005275934 /// XM_005276217 216878_x_at X83412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83412.1 /DEF=H.sapiens B1 mRNA for mucin. /FEA=mRNA /GEN=B1 /PROD=mucin /DB_XREF=gi:853955 /UG=Hs.100015 B1 for mucin X83412 B1 for mucin HAB1 55547 216879_at X91103 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X91103.1 /DEF=H.sapiens mRNA for Hr44 protein. /FEA=mRNA /GEN=hr44 /DB_XREF=gi:1054775 /UG=Hs.102131 Hr44 antigen X91103 0016021 // integral component of membrane // non-traceable author statement 216880_at Y15571 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15571.1 /DEF=Homo sapiens mRNA for recombination repair protein (R51H2). /FEA=mRNA /GEN=R51H2 /DB_XREF=gi:3005962 /UG=Hs.100669 RAD51 (S. cerevisiae)-like 1 Y15571 RAD51 paralog B RAD51B 5890 NM_002877 /// NM_133509 /// NM_133510 /// XM_005267961 /// XM_005267962 /// XM_005267963 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009432 // SOS response // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 216881_x_at X07882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07882 /DEF=Human PRB4 gene for proline-rich protein Po, allele S /FEA=mRNA /DB_XREF=gi:35647 /UG=Hs.103972 proline-rich protein BstNI subfamily 4 X07882 proline-rich protein BstNI subfamily 4 PRB4 5545 NM_001261399 /// NM_002723 0005576 // extracellular region // non-traceable author statement 216882_s_at AL157398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157398 /DEF=Human DNA sequence from clone RP11-56H7 on chromosome 10. Contains ESTs, STSs and GSSs. Contains the gene for the nebulette protein (NEBL, actin-binding Z-disc protein) /FEA=mRNA_2 /DB_XREF=gi:10045326 /UG=Hs.5025 nebulette AL157398 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 216883_x_at AJ001626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001626.1 /DEF=Homo sapiens mRNA for p17 protein. /FEA=mRNA /PROD=p17 protein /DB_XREF=gi:2695882 /UG=Hs.48291 phosphodiesterase 6D, cGMP-specific, rod, delta AJ001626 phosphodiesterase 6D, cGMP-specific, rod, delta PDE6D 5147 NM_001291018 /// NM_002601 /// NR_110994 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033124 // regulation of GTP catabolic process // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction 216884_at S69182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S69182.1 /DEF=Homo sapiens protein tyrosine phosphatase (PTPG1) mRNA, partial cds, alternatively spliced. /FEA=mRNA /GEN=PTPG1 /PROD=protein tyrosine phosphatase /DB_XREF=gi:545647 /UG=Hs.62 protein tyrosine phosphatase, non-receptor type 12 S69182 protein tyrosine phosphatase, non-receptor type 12 PTPN12 5782 NM_001131008 /// NM_001131009 /// NM_002835 /// XM_005250518 /// XM_006716073 /// XM_006716074 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction 216885_s_at AK026481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026481.1 /DEF=Homo sapiens cDNA: FLJ22828 fis, clone KAIA4051, highly similar to HSU06631 Human (H326) mRNA. /FEA=mRNA /DB_XREF=gi:10439353 /UG=Hs.110707 H326 AK026481 DDB1 and CUL4 associated factor 8 DCAF8 50717 NM_015726 /// NR_028103 /// NR_028104 /// NR_028105 /// NR_028106 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 216886_at X89745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89745.1 /DEF=H.sapiens mRNA for neuronal acetylcholine receptor alpha-4 subunit, exon 5. /FEA=mRNA /DB_XREF=gi:1279463 /UG=Hs.10734 cholinergic receptor, nicotinic, alpha polypeptide 4 X89745 cholinergic receptor, nicotinic, alpha 4 (neuronal) CHRNA4 1137 NM_000744 /// NM_001256573 /// NR_046317 /// XM_005260191 0001508 // action potential // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0035640 // exploration behavior // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 216887_s_at AJ133768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ133768.1 /DEF=Homo sapiens mRNA for ZASP protein, partial, varient 2. /FEA=mRNA /GEN=ZASP /PROD=ZASP protein /DB_XREF=gi:5441370 /UG=Hs.49998 Z-band alternatively spliced PDZ-motif AJ133768 LIM domain binding 3 LDB3 11155 NM_001080114 /// NM_001080115 /// NM_001080116 /// NM_001171610 /// NM_001171611 /// NM_007078 /// XM_005269464 /// XM_005269465 /// XM_005269466 /// XM_005269467 /// XM_005269468 /// XM_006717598 /// XM_006717599 /// XM_006717600 /// XM_006717601 0045214 // sarcomere organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation 216888_at AJ133768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ133768.1 /DEF=Homo sapiens mRNA for ZASP protein, partial, varient 2. /FEA=mRNA /GEN=ZASP /PROD=ZASP protein /DB_XREF=gi:5441370 /UG=Hs.49998 Z-band alternatively spliced PDZ-motif AJ133768 LIM domain binding 3 LDB3 11155 NM_001080114 /// NM_001080115 /// NM_001080116 /// NM_001171610 /// NM_001171611 /// NM_007078 /// XM_005269464 /// XM_005269465 /// XM_005269466 /// XM_005269467 /// XM_005269468 /// XM_006717598 /// XM_006717599 /// XM_006717600 /// XM_006717601 0045214 // sarcomere organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation 216889_s_at Z49825 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z49825.1 /DEF=H.sapiens mRNA for hepatocyte nuclear factor 4 alpha. /FEA=mRNA /PROD=hepatocyte nuclear factor 4 alpha (HNF4alpha4) /DB_XREF=gi:1217960 /UG=Hs.54424 hepatocyte nuclear factor 4, alpha Z49825 hepatocyte nuclear factor 4, alpha HNF4A 3172 NM_000457 /// NM_001030003 /// NM_001030004 /// NM_001258355 /// NM_001287182 /// NM_001287183 /// NM_001287184 /// NM_175914 /// NM_178849 /// NM_178850 /// XM_005260407 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006591 // ornithine metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from mutant phenotype /// 0007548 // sex differentiation // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0055088 // lipid homeostasis // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation /// 0060398 // regulation of growth hormone receptor signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 216890_at U00956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U00956.1 /DEF=Human clone KDB5.1 (CAC)n(GTG)n repeat-containing mRNA. /FEA=mRNA /DB_XREF=gi:405058 /UG=Hs.104112 Human clone KDB5.1 (CAC)n(GTG)n repeat-containing mRNA U00956 216891_at U00956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U00956.1 /DEF=Human clone KDB5.1 (CAC)n(GTG)n repeat-containing mRNA. /FEA=mRNA /DB_XREF=gi:405058 /UG=Hs.104112 Human clone KDB5.1 (CAC)n(GTG)n repeat-containing mRNA U00956 216892_at S65761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S65761.1 /DEF=anti-colorectal carcinoma heavy chain=glycoprotein CANAG-50 specific IgG1 kappa human, 19.9 hybridoma, antibody 1116NS19.9, mRNA, 1515 nt. /FEA=mRNA /GEN=anti-colorectal carcinoma heavy chain /PROD=anti-colorectal carcinoma heavy chain /DB_XREF=gi:425517 /UG=Hs.103995 Anti-colorectal carcinoma heavy chain S65761 immunoglobulin heavy constant gamma 1 (G1m marker) IGHG1 3500 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 216893_s_at U02519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02519.1 /DEF=Human collagen type IV alpha 3 alternatively spliced mRNA, partial cds. /FEA=mRNA /PROD=collagen type IV alpha 3 /DB_XREF=gi:409106 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) U02519 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 216894_x_at D64137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D64137 /DEF=Human KIP2 gene for Cdk-inhibitor p57KIP2, complete cds (exon1-4) /FEA=mRNA_4 /DB_XREF=gi:992945 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) D64137 cyclin-dependent kinase inhibitor 1C (p57, Kip2) CDKN1C 1028 NM_000076 /// NM_001122630 /// NM_001122631 /// XM_005252731 /// XM_005252732 /// XM_006725125 /// XM_006725126 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000080 // mitotic G1 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 216895_at S82769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S82769.1 /DEF=GABAA receptor gamma 3 subunit human, fetal brain, mRNA Partial, 1536 nt. /FEA=mRNA /GEN=GABAA receptor gamma 3 subunit /PROD=GABAA receptor gamma 3 subunit /DB_XREF=gi:1754748 /UG=Hs.104133 GABAA receptor gamma 3 subunit human, fetal brain, mRNA Partial, 1536 nt S82769 gamma-aminobutyric acid (GABA) A receptor, gamma 3 GABRG3 2567 NM_001270873 /// NM_033223 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation 216896_at U02519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02519.1 /DEF=Human collagen type IV alpha 3 alternatively spliced mRNA, partial cds. /FEA=mRNA /PROD=collagen type IV alpha 3 /DB_XREF=gi:409106 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) U02519 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 216897_s_at AL035309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035309.1 /DEF=H.sapiens gene from PAC 426I6. /FEA=CDS /PROD=hypothetical protein /DB_XREF=gi:4200237 /UG=Hs.105911 H.sapiens gene from PAC 426I6 AL035309 family with sequence similarity 76, member A FAM76A 199870 NM_001143912 /// NM_001143913 /// NM_001143914 /// NM_001143915 /// NM_152660 216898_s_at U02520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U02520.1 /DEF=Human collagen type IV alpha 3 mRNA, partial cds. /FEA=mRNA /PROD=collagen type IV alpha 3 /DB_XREF=gi:408895 /UG=Hs.530 collagen, type IV, alpha 3 (Goodpasture antigen) U02520 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 216899_s_at AC003999 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003999 /DEF=Human PAC clone RP5-1139P1 from 7p15-p21 /FEA=CDS /DB_XREF=gi:2772566 /UG=Hs.52644 SKAP55 homologue AC003999 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 216900_s_at X89745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89745.1 /DEF=H.sapiens mRNA for neuronal acetylcholine receptor alpha-4 subunit, exon 5. /FEA=mRNA /DB_XREF=gi:1279463 /UG=Hs.10734 cholinergic receptor, nicotinic, alpha polypeptide 4 X89745 cholinergic receptor, nicotinic, alpha 4 (neuronal) CHRNA4 1137 NM_000744 /// NM_001256573 /// NR_046317 /// XM_005260191 0001508 // action potential // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // non-traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from sequence or structural similarity /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from sequence or structural similarity /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035095 // behavioral response to nicotine // inferred from mutant phenotype /// 0035640 // exploration behavior // inferred from electronic annotation /// 0042113 // B cell activation // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from direct assay /// 0004889 // acetylcholine-activated cation-selective channel activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // inferred from direct assay /// 0042166 // acetylcholine binding // inferred by curator 216901_s_at S80876 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S80876.1 /DEF=IKAROS=hIk1 {alternatively spliced} human, Jurkat T cell line, mRNA Partial, 1788 nt. /FEA=CDS /GEN=IKAROS /PROD=hIk1 /DB_XREF=gi:1911482 /UG=Hs.54452 zinc finger protein, subfamily 1A, 1 (Ikaros) S80876 IKAROS family zinc finger 1 (Ikaros) IKZF1 10320 NM_001220765 /// NM_001220766 /// NM_001220767 /// NM_001220768 /// NM_001220769 /// NM_001220770 /// NM_001220771 /// NM_001220772 /// NM_001220773 /// NM_001220774 /// NM_001220775 /// NM_001220776 /// NM_001291837 /// NM_001291838 /// NM_001291839 /// NM_001291840 /// NM_001291841 /// NM_001291842 /// NM_001291843 /// NM_001291844 /// NM_001291845 /// NM_001291846 /// NM_001291847 /// NM_006060 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045660 // positive regulation of neutrophil differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216902_s_at AF001549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF001549 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-270G1 /FEA=mRNA_1 /DB_XREF=gi:3355302 /UG=Hs.110103 RNA polymerase I transcription factor RRN3 AF001549 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) /// RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 /// RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2 RRN3 /// RRN3P1 /// RRN3P2 54700 /// 653390 /// 730092 NM_018427 /// NR_003369 /// NR_003370 /// XM_005255375 /// XM_005255376 /// XM_005255377 /// XM_006725197 /// XM_006725198 /// XM_006725199 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 1902254 // negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 2000142 // regulation of DNA-templated transcription, initiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0070063 // RNA polymerase binding // inferred from electronic annotation 216903_s_at AK022697 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022697.1 /DEF=Homo sapiens cDNA FLJ12635 fis, clone NT2RM4001865, highly similar to Homo sapiens mRNA for atopy related autoantigen CALC. /FEA=mRNA /DB_XREF=gi:10434244 /UG=Hs.61628 calcium binding atopy-related autoantigen 1 AK022697 mitochondrial calcium uptake 1 MICU1 10367 NM_001195518 /// NM_001195519 /// NM_006077 /// XM_005269383 /// XM_005269384 /// XM_005269386 /// XM_005269387 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006851 // mitochondrial calcium ion transport // inferred from direct assay /// 0006851 // mitochondrial calcium ion transport // inferred from mutant phenotype /// 0006952 // defense response // traceable author statement /// 0036444 // calcium ion import into mitochondrion // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051560 // mitochondrial calcium ion homeostasis // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from direct assay /// 0070509 // calcium ion import // inferred from direct assay 0005622 // intracellular // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay /// 0034704 // calcium channel complex // inferred from sequence or structural similarity /// 1990246 // uniplex complex // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 216904_at X15880 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X15880.1 /DEF=Human mRNA for collagen VI alpha-1 C-terminal globular domain. /FEA=mRNA /PROD=alpha-1 collagen VI (AA 574-1009) /DB_XREF=gi:30029 /UG=Hs.108885 collagen, type VI, alpha 1 X15880 collagen, type VI, alpha 1 COL6A1 1291 NM_001848 /// XM_006723964 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0070208 // protein heterotrimerization // inferred from physical interaction /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0048407 // platelet-derived growth factor binding // inferred from direct assay 216905_s_at U20428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U20428.1 /DEF=Human SNC19 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1890631 /UG=Hs.56937 suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) U20428 suppression of tumorigenicity 14 (colon carcinoma) ST14 6768 NM_021978 0006508 // proteolysis // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 216906_at U20428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U20428.1 /DEF=Human SNC19 mRNA sequence. /FEA=mRNA /DB_XREF=gi:1890631 /UG=Hs.56937 suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) U20428 suppression of tumorigenicity 14 (colon carcinoma) ST14 6768 NM_021978 0006508 // proteolysis // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 216907_x_at X93596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X93596.1 /DEF=H.sapiens mRNA for HLA specific NK receptor. /FEA=mRNA /PROD=NK receptor /DB_XREF=gi:1495476 /UG=Hs.56328 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 X93596 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 KIR3DL1 /// KIR3DL2 3811 /// 3812 NM_001242867 /// NM_006737 /// NM_013289 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030109 // HLA-B specific inhibitory MHC class I receptor activity // non-traceable author statement 216908_x_at AF001549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF001549 /DEF=Human Chromosome 16 BAC clone CIT987SK-A-270G1 /FEA=mRNA_2 /DB_XREF=gi:3355302 /UG=Hs.110103 RNA polymerase I transcription factor RRN3 AF001549 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 RRN3P1 730092 NR_003370 0006413 // translational initiation // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred from electronic annotation 216909_at AK021460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021460.1 /DEF=Homo sapiens cDNA FLJ11398 fis, clone HEMBA1000637. /FEA=mRNA /DB_XREF=gi:10432652 /UG=Hs.60103 KIAA0690 protein AK021460 ribosomal RNA processing 12 homolog (S. cerevisiae) RRP12 23223 NM_001145114 /// NM_001284337 /// NM_015179 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 216910_at AF195953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF195953 /DEF=Homo sapiens membrane-bound aminopeptidase P (XNPEP2) gene, complete cds /FEA=mRNA /DB_XREF=gi:11066156 /UG=Hs.57922 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound AF195953 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound XPNPEP2 7512 NM_003399 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216911_s_at AL162003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162003.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F0616 (from clone DKFZp434F0616); partial cds. /FEA=mRNA /GEN=DKFZp434F0616 /PROD=hypothetical protein /DB_XREF=gi:7328027 /UG=Hs.109445 KIAA1020 protein AL162003 hypermethylated in cancer 2 HIC2 23119 NM_015094 /// XM_005261395 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216912_at AB029035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029035.1 /DEF=Homo sapiens mRNA for KIAA1112 protein, partial cds. /FEA=mRNA /GEN=KIAA1112 /PROD=KIAA1112 protein /DB_XREF=gi:5689560 /UG=Hs.6066 Rho guanine nucleotide exchange factor (GEF) 4 AB029035 Rho guanine nucleotide exchange factor (GEF) 4 ARHGEF4 50649 NM_015320 /// NM_032995 /// XM_005263681 /// XM_005263682 /// XM_005263683 /// XM_005263685 /// XM_005263686 /// XM_005263687 /// XM_005263688 /// XM_005263689 /// XR_244821 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype 216913_s_at AK021460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021460.1 /DEF=Homo sapiens cDNA FLJ11398 fis, clone HEMBA1000637. /FEA=mRNA /DB_XREF=gi:10432652 /UG=Hs.60103 KIAA0690 protein AK021460 ribosomal RNA processing 12 homolog (S. cerevisiae) RRP12 23223 NM_001145114 /// NM_001284337 /// NM_015179 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216914_at AF277724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF277724.1 /DEF=Homo sapiens cell division cycle 25C splice variant 3 (CDC25C) mRNA, partial cds. /FEA=mRNA /GEN=CDC25C /PROD=cell division cycle 25C splice variant 3 /DB_XREF=gi:11934924 /UG=Hs.656 cell division cycle 25C AF277724 cell division cycle 25C CDC25C 995 NM_001287582 /// NM_001287583 /// NM_001790 /// NM_022809 /// XM_005272145 /// XM_005272146 /// XM_006714739 /// XM_006714740 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from genetic interaction /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 216915_s_at S69182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S69182.1 /DEF=Homo sapiens protein tyrosine phosphatase (PTPG1) mRNA, partial cds, alternatively spliced. /FEA=mRNA /GEN=PTPG1 /PROD=protein tyrosine phosphatase /DB_XREF=gi:545647 /UG=Hs.62 protein tyrosine phosphatase, non-receptor type 12 S69182 protein tyrosine phosphatase, non-receptor type 12 PTPN12 5782 NM_001131008 /// NM_001131009 /// NM_002835 /// XM_005250518 /// XM_006716073 /// XM_006716074 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction 216916_s_at AF009204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009204.1 /DEF=Homo sapiens PSD-95SAP90-associated protein-2 mRNA, partial cds. /FEA=mRNA /PROD=PSD-95SAP90-associated protein-2 /DB_XREF=gi:2454509 /UG=Hs.113287 discs, large (Drosophila) homolog-associated protein 2 AF009204 discs, large (Drosophila) homolog-associated protein 2 DLGAP2 9228 NM_001277161 /// NM_004745 /// XM_005266038 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // non-traceable author statement 0005883 // neurofilament // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 216917_s_at X95654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95654.1 /DEF=H.sapiens mRNA for SCP1 protein. /FEA=mRNA /GEN=SCP1 /PROD=polypeptide of 976 aa /DB_XREF=gi:1212982 /UG=Hs.112743 synaptonemal complex protein 1 X95654 synaptonemal complex protein 1 SYCP1 6847 NM_001282541 /// NM_001282542 /// NM_003176 /// NR_104211 /// XM_005271154 /// XM_005271155 /// XM_005271156 /// XM_006710859 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000795 // synaptonemal complex // inferred from electronic annotation /// 0000801 // central element // inferred from electronic annotation /// 0000802 // transverse filament // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 216918_s_at AL096710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096710 /DEF=Human DNA sequence from clone RP1-61B2 on chromosome 6p11.2-12.3 Contains isoforms 1 and 3 of BPAG1 (bullous pemphigoid antigen 1 (230240kD), an exon of a gene similar to murine MACF cytoskeletal protein, STSs and GSSs /FEA=CDS /DB_XREF=gi:5738652 /UG=Hs.620 bullous pemphigoid antigen 1 (230240kD) AL096710 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 216919_at U79302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79302.1 /DEF=Human clone 23855 mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1710287 /UG=Hs.73182 Human clone 23855 mRNA, partial cds U79302 tumor protein p53 inducible protein 11 TP53I11 9537 NM_001076787 /// NM_001258320 /// NM_001258321 /// NM_001258322 /// NM_001258323 /// NM_001258324 /// NM_006034 /// XM_005253227 /// XM_005253229 /// XM_006718387 /// XR_242833 /// XR_428864 0006950 // response to stress // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 216920_s_at M27331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M27331.1 /DEF=Homo sapiens (clone HGP08) T cell receptor gamma-chain mRNA, C2 region. /FEA=mRNA /GEN=TCRGC2 /DB_XREF=gi:540458 /UG=Hs.112259 T cell receptor gamma locus M27331 TCR gamma alternate reading frame protein /// T cell receptor gamma constant 2 /// T cell receptor gamma variable 9 TARP /// TRGC2 /// TRGV9 6967 /// 6983 /// 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 216921_s_at X90763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X90763.1 /DEF=Homo sapiens mRNA for type I keratin. /FEA=mRNA /GEN=hHa5 /PROD=HHa5 hair keratin type I intermediate filament /DB_XREF=gi:1668743 /UG=Hs.73082 keratin, hair, acidic, 5 X90763 keratin 35 KRT35 3886 NM_002280 0009653 // anatomical structure morphogenesis // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 216922_x_at AF271088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF271088.1 /DEF=Homo sapiens deleted in azoospermia (DAZ) mRNA, partial cds. /FEA=mRNA /GEN=DAZ /PROD=deleted in azoospermia /DB_XREF=gi:9652116 /UG=Hs.70936 deleted in azoospermia AF271088 deleted in azoospermia 1 /// deleted in azoospermia 2 /// deleted in azoospermia 3 /// deleted in azoospermia 4 DAZ1 /// DAZ2 /// DAZ3 /// DAZ4 1617 /// 57054 /// 57055 /// 57135 NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 /// XM_005262578 /// XM_005262579 /// XM_005262602 /// XM_005262604 /// XM_005262605 /// XM_005262606 /// XM_006709927 /// XM_006709928 /// XR_250607 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay 216923_at AL049684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049684.1 /DEF=Isoform of XLRS1 gene from PAC 245G19, chromosome X. /FEA=mRNA /DB_XREF=gi:4678742 /UG=Hs.113250 retinoschisis (X-linked, juvenile) 1 AL049684 cyclin-dependent kinase-like 5 CDKL5 6792 NM_001037343 /// NM_003159 /// XM_005274584 /// XM_005274585 /// XM_006724511 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050773 // regulation of dendrite development // inferred from sequence or structural similarity /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0032839 // dendrite cytoplasm // inferred from sequence or structural similarity /// 0044294 // dendritic growth cone // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity 216924_s_at S62137 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S62137.1 /DEF=D2 dopamine receptor human, mRNA, 2460 nt. /FEA=mRNA /GEN=D2 dopamine receptor /PROD=D2 dopamine receptor /DB_XREF=gi:405309 /UG=Hs.73893 dopamine receptor D2 S62137 dopamine receptor D2 DRD2 1813 NM_000795 /// NM_016574 /// XM_005271425 /// XM_006718774 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from sequence or structural similarity /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014854 // response to inactivity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0021984 // adenohypophysis development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0034776 // response to histamine // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from sequence or structural similarity /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046717 // acid secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from sequence or structural similarity /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060124 // positive regulation of growth hormone secretion // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from genetic interaction /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation /// 1900273 // positive regulation of long-term synaptic potentiation // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0035240 // dopamine binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216925_s_at X51990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X51990.1 /DEF=H.sapiens TAL1 mRNA. /FEA=mRNA /PROD=tal1 /DB_XREF=gi:36679 /UG=Hs.73828 T-cell acute lymphocytic leukemia 1 X51990 T-cell acute lymphocytic leukemia 1 TAL1 6886 NM_001287347 /// NM_001290403 /// NM_001290404 /// NM_001290405 /// NM_001290406 /// NM_003189 /// XM_005271158 /// XM_005271159 /// XM_005271160 /// XM_006710862 /// XM_006710863 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030219 // megakaryocyte differentiation // inferred from expression pattern /// 0030220 // platelet formation // inferred from electronic annotation /// 0030221 // basophil differentiation // inferred from expression pattern /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045799 // positive regulation of chromatin assembly or disassembly // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048699 // generation of neurons // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060217 // hemangioblast cell differentiation // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060375 // regulation of mast cell differentiation // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0033193 // Lsd1/2 complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 216926_s_at AC003030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003030 /DEF=Homo sapiens chromosome 19, overlapping cosmids R29828 and F25496 /FEA=CDS /DB_XREF=gi:4092821 /UG=Hs.112751 KIAA0892 protein AC003030 MAU2 sister chromatid cohesion factor MAU2 23383 NM_015329 /// XM_005259837 /// XM_005259838 /// XM_006722711 /// XR_430132 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0032116 // SMC loading complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 216927_at AC003030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003030 /DEF=Homo sapiens chromosome 19, overlapping cosmids R29828 and F25496 /FEA=CDS /DB_XREF=gi:4092821 /UG=Hs.112751 KIAA0892 protein AC003030 MAU2 sister chromatid cohesion factor MAU2 23383 NM_015329 /// XM_005259837 /// XM_005259838 /// XM_006722711 /// XR_430132 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0032116 // SMC loading complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 216928_at X51990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X51990.1 /DEF=H.sapiens TAL1 mRNA. /FEA=mRNA /PROD=tal1 /DB_XREF=gi:36679 /UG=Hs.73828 T-cell acute lymphocytic leukemia 1 X51990 T-cell acute lymphocytic leukemia 1 TAL1 6886 NM_001287347 /// NM_001290403 /// NM_001290404 /// NM_001290405 /// NM_001290406 /// NM_003189 /// XM_005271158 /// XM_005271159 /// XM_005271160 /// XM_006710862 /// XM_006710863 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030219 // megakaryocyte differentiation // inferred from expression pattern /// 0030220 // platelet formation // inferred from electronic annotation /// 0030221 // basophil differentiation // inferred from expression pattern /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045799 // positive regulation of chromatin assembly or disassembly // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048699 // generation of neurons // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from mutant phenotype /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0060217 // hemangioblast cell differentiation // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060375 // regulation of mast cell differentiation // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0033193 // Lsd1/2 complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 216929_x_at U15197 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U15197.1 /DEF=Human histo-blood group ABO protein mRNA, partial 3 UTR sequence. /FEA=mRNA /GEN=ABO /DB_XREF=gi:595854 /UG=Hs.113271 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) U15197 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) ABO 28 NM_020469 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0004380 // glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0004381 // fucosylgalactoside 3-alpha-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216930_at X71347 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X71347.1 /DEF=H.sapiens HNF1-C mRNA. /FEA=mRNA /DB_XREF=gi:416527 /UG=Hs.73888 transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor X71347 HNF1 homeobox A HNF1A 6927 NM_000545 /// XM_005253931 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from mutant phenotype /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0035565 // regulation of pronephros size // inferred from mutant phenotype /// 0035623 // renal glucose absorption // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046323 // glucose import // inferred from mutant phenotype /// 0046883 // regulation of hormone secretion // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from genetic interaction /// 0060395 // SMAD protein signal transduction // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from physical interaction 216931_at L23852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L23852.1 /DEF=Homo sapiens (clone Z146) retinal mRNA, 3 end and repeat region. /FEA=mRNA /DB_XREF=gi:393126 /UG=Hs.73838 Homo sapiens (clone Z146) retinal mRNA, 3 end and repeat region L23852 216932_at M20919 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M20919 /DEF=Human DNA with a hepatitis B virus surface antigen (HBsAg) gene (complete cds) insertion /FEA=CDS /DB_XREF=gi:184331 /UG=Hs.113220 Human DNA with a hepatitis B virus surface antigen (HBsAg) gene (complete cds) insertion M20919 216933_x_at S67788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S67788.1 /DEF=APC human, adenomatous polyposis coli kindreds 347 and 139, mRNA Partial Mutant, 117 nt. /FEA=mRNA /GEN=APC /DB_XREF=gi:461062 /UG=Hs.75081 adenomatosis polyposis coli S67788 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 216934_at X81637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81637.1 /DEF=H.sapiens clathrin light chain b gene. /FEA=mRNA /DB_XREF=gi:963046 /UG=Hs.73919 clathrin, light polypeptide (Lcb) X81637 216935_at AF005082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005082.1 /DEF=Homo sapiens skin-specific protein (xp33) mRNA, partial cds. /FEA=mRNA /GEN=xp33 /PROD=skin-specific protein /DB_XREF=gi:2589191 /UG=Hs.113261 Homo sapiens skin-specific protein (xp33) mRNA, partial cds AF005082 long intergenic non-protein coding RNA 302 LINC00302 388699 216936_at X81637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X81637.1 /DEF=H.sapiens clathrin light chain b gene. /FEA=mRNA /DB_XREF=gi:963046 /UG=Hs.73919 clathrin, light polypeptide (Lcb) X81637 216937_s_at AL049684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049684.1 /DEF=Isoform of XLRS1 gene from PAC 245G19, chromosome X. /FEA=mRNA /DB_XREF=gi:4678742 /UG=Hs.113250 retinoschisis (X-linked, juvenile) 1 AL049684 retinoschisin 1 RS1 6247 NM_000330 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016062 // adaptation of rhodopsin mediated signaling // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from electronic annotation /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from electronic annotation /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from electronic annotation /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from electronic annotation 216938_x_at S69899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S69899.1 /DEF=D2 dopamine receptor human, retina, mRNA, 2474 nt. /FEA=mRNA /GEN=D2 dopamine receptor /PROD=D2 dopamine receptor /DB_XREF=gi:240290 /UG=Hs.73893 dopamine receptor D2 S69899 dopamine receptor D2 DRD2 1813 NM_000795 /// NM_016574 /// XM_005271425 /// XM_006718774 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from sequence or structural similarity /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0002031 // G-protein coupled receptor internalization // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from direct assay /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009416 // response to light stimulus // inferred from sequence or structural similarity /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014854 // response to inactivity // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0021984 // adenohypophysis development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from sequence or structural similarity /// 0030534 // adult behavior // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033602 // negative regulation of dopamine secretion // inferred from electronic annotation /// 0034776 // response to histamine // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from sequence or structural similarity /// 0042321 // negative regulation of circadian sleep/wake cycle, sleep // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred by curator /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0043266 // regulation of potassium ion transport // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from sequence or structural similarity /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046717 // acid secretion // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred by curator /// 0051586 // positive regulation of dopamine uptake involved in synaptic transmission // inferred from sequence or structural similarity /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0051967 // negative regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060124 // positive regulation of growth hormone secretion // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from genetic interaction /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from electronic annotation /// 1900273 // positive regulation of long-term synaptic potentiation // inferred from electronic annotation /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0035240 // dopamine binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216939_s_at Y08756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y08756.1 /DEF=H.sapiens mRNA for serotonin receptor 5-HT4. /FEA=mRNA /PROD=serotonin 5-HT receptor /DB_XREF=gi:2661732 /UG=Hs.113262 5-hydroxytryptamine (serotonin) receptor 4 Y08756 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled HTR4 3360 NM_000870 /// NM_001040169 /// NM_001040172 /// NM_001040173 /// NM_001040174 /// NM_001286410 /// NM_199453 /// NR_104445 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0032098 // regulation of appetite // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay 216940_x_at X96666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X96666 /DEF=H.sapiens YB-1 gene promoter region /FEA=CDS /DB_XREF=gi:1403348 /UG=Hs.74497 nuclease sensitive element binding protein 1 X96666 Y box binding protein 1 YBX1 4904 NM_004559 /// XM_005270904 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216941_s_at AK026521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026521.1 /DEF=Homo sapiens cDNA: FLJ22868 fis, clone KAT02340, highly similar to HUMTFSL1C Homo sapiens transcription factor SL1 mRNA. /FEA=mRNA /DB_XREF=gi:10439398 /UG=Hs.121044 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD AK026521 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa TAF1B 9014 NM_005680 0001189 // RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript // inferred from direct assay /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070860 // RNA polymerase I core factor complex // inferred from direct assay 0001164 // RNA polymerase I CORE element sequence-specific DNA binding // inferred from direct assay /// 0001187 // RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216942_s_at D28586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D28586.1 /DEF=Human mRNA for LFA-3(delta D2), partial cds. /FEA=mRNA /PROD=LFA-3(delta D2) /DB_XREF=gi:466540 /UG=Hs.75626 CD58 antigen, (lymphocyte function-associated antigen 3) D28586 CD58 molecule CD58 965 NM_001144822 /// NM_001779 /// NR_026665 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 216943_at AF095723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF095723.1 /DEF=Homo sapiens GABA-B receptor splice variant 1 mRNA, partial cds. /FEA=mRNA /PROD=GABA-B receptor splice variant 1 /DB_XREF=gi:3719471 /UG=Hs.198612 G protein-coupled receptor 51 AF095723 216944_s_at U23850 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U23850.1 /DEF=Human inositol 1,4,5 trisphosphate receptor type 1 mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:915324 /UG=Hs.198443 inositol 1,4,5-triphosphate receptor, type 1 U23850 inositol 1,4,5-trisphosphate receptor, type 1 ITPR1 3708 NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity 216945_x_at U79240 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U79240.1 /DEF=Human serinethreonine kinase mRNA, partial cds. /FEA=mRNA /PROD=serinethreonine protein kinase /DB_XREF=gi:1710185 /UG=Hs.79337 KIAA0135 protein U79240 PAS domain containing serine/threonine kinase PASK 23178 NM_001252119 /// NM_001252120 /// NM_001252122 /// NM_001252124 /// NM_015148 /// XM_005246990 /// XM_005246991 /// XR_427079 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043576 // regulation of respiratory gaseous exchange // inferred from sequence or structural similarity /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045727 // positive regulation of translation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0070092 // regulation of glucagon secretion // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 216946_at M29335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M29335.1 /DEF=Human MHC class II DO-alpha mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:188002 /UG=Hs.123041 Human MHC class II DO-alpha mRNA, partial cds M29335 major histocompatibility complex, class II, DO alpha HLA-DOA 3111 NM_002119 /// XM_005249047 /// XM_005272804 /// XM_005274951 /// XM_005275106 /// XM_005275243 /// XM_005275383 /// XM_005275540 /// XM_006715076 /// XM_006725483 /// XM_006725697 /// XM_006725815 /// XM_006725906 /// XM_006725996 /// XM_006726086 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002587 // negative regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement 216947_at AK022087 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022087.1 /DEF=Homo sapiens cDNA FLJ12025 fis, clone HEMBB1001802, highly similar to Human desmin mRNA. /FEA=mRNA /DB_XREF=gi:10433408 /UG=Hs.279604 desmin AK022087 desmin DES 1674 NM_001927 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 216948_at AL049545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049545 /DEF=Human DNA sequence from clone 263J7 on chromosome 6q14.3-15. Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, a RAB1 (RAB1, member RAS oncogene family) pseudogene, ESTs, an STS and GSSs /FEA=CDS_2 /DB_XREF=gi:5002650 /UG=Hs.247878 Human DNA sequence from clone 263J7 on chromosome 6q14.3-15. Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, a RAB1 (RAB1, member RAS oncogene family) pseudogene, ESTs, an STS and GSSs AL049545 RP1-263J7.2 216949_s_at L39891 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L39891 /DEF=Homo sapiens polycystic kidney disease-associated protein (PKD1) gene, complete cds /FEA=CDS /DB_XREF=gi:790818 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) L39891 polycystin-1-like /// polycystic kidney disease 1 (autosomal dominant) LOC101930075 /// PKD1 5310 /// 101930075 NM_000296 /// NM_001009944 /// XM_005255370 /// XM_005276493 /// XM_006720889 /// XM_006720890 /// XM_006720891 /// XM_006720892 /// XM_006720893 /// XM_006720894 /// XM_006720895 /// XR_429642 /// XR_429643 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // not recorded /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 216950_s_at X14355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14355.1 /DEF=Human mRNA for high affinity Fc receptor (FcRI) b form. /FEA=mRNA /DB_XREF=gi:31333 /UG=Hs.77424 Fc fragment of IgG, high affinity Ia, receptor for (CD64) X14355 Fc fragment of IgG, high affinity Ia, receptor (CD64) /// Fc fragment of IgG, high affinity Ib, receptor (CD64) /// Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene FCGR1A /// FCGR1B /// FCGR1C 2209 /// 2210 /// 100132417 NM_000566 /// NM_001004340 /// NM_001017986 /// NM_001128589 /// NM_001244910 /// NR_027484 /// NR_045213 /// XM_005244957 /// XM_005244958 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006911 // phagocytosis, engulfment // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038093 // Fc receptor signaling pathway // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019763 // immunoglobulin receptor activity // non-traceable author statement /// 0019864 // IgG binding // inferred from electronic annotation 216951_at X14355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14355.1 /DEF=Human mRNA for high affinity Fc receptor (FcRI) b form. /FEA=mRNA /DB_XREF=gi:31333 /UG=Hs.77424 Fc fragment of IgG, high affinity Ia, receptor for (CD64) X14355 Fc fragment of IgG, high affinity Ia, receptor (CD64) FCGR1A 2209 NM_000566 /// XM_005244957 /// XM_005244958 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006911 // phagocytosis, engulfment // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019864 // IgG binding // inferred from electronic annotation 216952_s_at M94363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M94363 /DEF=Human lamin B2 (LAMB2) gene and ppv1 gene sequence /FEA=mRNA /DB_XREF=gi:186920 /UG=Hs.76084 lamin B2 M94363 lamin B2 LMNB2 84823 NM_032737 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005638 // lamin filament // inferred from electronic annotation /// 0005652 // nuclear lamina // non-traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 216953_s_at S75264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S75264.1 /DEF=WT1=Wilms tumor suppressor protein human, fetal kidney, mRNA, 521 nt. /FEA=mRNA /GEN=WT1 /PROD=WT1 /DB_XREF=gi:896246 /UG=Hs.1145 Wilms tumor 1 S75264 Wilms tumor 1 WT1 7490 NM_000378 /// NM_001198551 /// NM_001198552 /// NM_024424 /// NM_024425 /// NM_024426 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from genetic interaction /// 0001822 // kidney development // inferred from genetic interaction /// 0001823 // mesonephros development // inferred from electronic annotation /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007281 // germ cell development // inferred from sequence or structural similarity /// 0007356 // thorax and anterior abdomen determination // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from genetic interaction /// 0007530 // sex determination // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008406 // gonad development // inferred from sequence or structural similarity /// 0008584 // male gonad development // inferred from expression pattern /// 0009888 // tissue development // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030325 // adrenal gland development // inferred from genetic interaction /// 0030539 // male genitalia development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from genetic interaction /// 0032836 // glomerular basement membrane development // inferred from mutant phenotype /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0060421 // positive regulation of heart growth // inferred from sequence or structural similarity /// 0060539 // diaphragm development // inferred from sequence or structural similarity /// 0060923 // cardiac muscle cell fate commitment // inferred from sequence or structural similarity /// 0061032 // visceral serous pericardium development // inferred from genetic interaction /// 0071320 // cellular response to cAMP // inferred from expression pattern /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // not recorded /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 0072166 // posterior mesonephric tubule development // inferred from sequence or structural similarity /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from genetic interaction /// 0072302 // negative regulation of metanephric glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2000195 // negative regulation of female gonad development // inferred from sequence or structural similarity /// 2001076 // positive regulation of metanephric ureteric bud development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 216954_x_at S77356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S77356.1 /DEF=Homo sapiens oligomycin sensitivity conferral protein oscp-like protein mRNA, partial cds. /FEA=mRNA /PROD=oligomycin sensitivity conferral proteinoscp-like protein /DB_XREF=gi:944964 /UG=Hs.76572 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) S77356 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit ATP5O 539 NM_001697 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred from mutant phenotype /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation 216955_at X07024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07024.1 /DEF=Human X chromsome mRNA for CCG1 protein inv. in cell proliferation. /FEA=mRNA /DB_XREF=gi:29732 /UG=Hs.1179 TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 250kD X07024 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa TAF1 6872 NM_001286074 /// NM_004606 /// NM_138923 /// NR_104387 /// NR_104388 /// NR_104389 /// NR_104390 /// NR_104391 /// NR_104392 /// NR_104393 /// NR_104394 /// NR_104395 /// NR_104396 /// XM_005262295 /// XM_005262296 /// XM_005262297 /// XM_005262300 /// XM_006724680 /// XM_006724681 /// XM_006724682 0000117 // regulation of transcription involved in G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from sequence or structural similarity /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 216956_s_at AF098114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF098114.1 /DEF=Homo sapiens truncated alpha IIb protein mRNA, partial cds. /FEA=mRNA /PROD=truncated alpha IIb protein /DB_XREF=gi:4063696 /UG=Hs.785 integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) AF098114 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ITGA2B 3674 NM_000419 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0070527 // platelet aggregation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 216957_at AL162082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162082.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1822 (from clone DKFZp434K1822); partial cds. /FEA=mRNA /GEN=DKFZp434K1822 /PROD=hypothetical protein /DB_XREF=gi:7328167 /UG=Hs.12064 ubiquitin specific protease 22 AL162082 ubiquitin specific peptidase 22 USP22 23326 NM_015276 /// XM_005256575 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216958_s_at AK022777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022777.1 /DEF=Homo sapiens cDNA FLJ12715 fis, clone NT2RP1001185, highly similar to Human isovaleryl-coA dehydrogenase (IVD) mRNA. /FEA=mRNA /DB_XREF=gi:10434377 /UG=Hs.77510 isovaleryl Coenzyme A dehydrogenase AK022777 isovaleryl-CoA dehydrogenase IVD 3712 NM_001159508 /// NM_002225 /// XM_005254350 /// XM_005254356 /// XM_006720491 /// XM_006720492 /// XM_006720493 /// XM_006720494 /// XM_006720495 /// XR_243097 /// XR_243098 /// XR_429453 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0008470 // isovaleryl-CoA dehydrogenase activity // not recorded /// 0008470 // isovaleryl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 216959_x_at U55258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U55258 /DEF=Human hBRAVONr-CAM precursor (hBRAVONr-CAM) gene, complete cds /FEA=CDS /DB_XREF=gi:1621282 /UG=Hs.7912 neuronal cell adhesion molecule U55258 neuronal cell adhesion molecule NRCAM 4897 NM_001037132 /// NM_001037133 /// NM_001193582 /// NM_001193583 /// NM_001193584 /// NM_005010 /// XM_005250373 /// XM_005250380 /// XM_005250383 /// XM_005250385 /// XM_006716003 /// XM_006716004 /// XM_006716005 /// XM_006716006 /// XM_006716007 /// XM_006716008 /// XM_006716009 /// XM_006716010 /// XM_006716011 /// XM_006716012 /// XM_006716013 /// XM_006716014 /// XR_428177 /// XR_428178 0001525 // angiogenesis // inferred from expression pattern /// 0001764 // neuron migration // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // non-traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0030516 // regulation of axon extension // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0045162 // clustering of voltage-gated sodium channels // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation 216960_s_at AL049646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049646 /DEF=Human DNA sequence from clone RP4-568F9 on chromosome 20 Contains the ZNF133 (zinc finger protein 133 (clone pHZ-13)) gene, part of a gene for a novel protein, ESTs, STSs, GSSs and CpG islands /FEA=mRNA_2 /DB_XREF=gi:11121205 /UG=Hs.78434 zinc finger protein 133 (clone pHZ-13) AL049646 zinc finger protein 133 ZNF133 7692 NM_001083330 /// NM_001282995 /// NM_001282996 /// NM_001282997 /// NM_001282998 /// NM_001282999 /// NM_001283000 /// NM_001283001 /// NM_001283002 /// NM_001283003 /// NM_001283004 /// NM_001283005 /// NM_001283006 /// NM_001283007 /// NM_001283008 /// NM_003434 /// XM_005260818 /// XM_005260819 /// XM_005260820 /// XM_005260823 /// XM_006723616 /// XM_006723617 /// XM_006723618 /// XM_006723619 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216961_s_at M69039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M69039.1 /DEF=Human pre-mRNA splicing factor SF2p32, complete sequence. /FEA=mRNA /DB_XREF=gi:338042 /UG=Hs.78614 complement component 1, q subcomponent binding protein M69039 RPA interacting protein RPAIN 84268 NM_001033002 /// NM_001160243 /// NM_001160244 /// NM_001160246 /// NM_001160266 /// NM_001160267 /// NM_032308 /// NR_027678 /// NR_027679 /// NR_027680 /// NR_027681 /// NR_027682 /// NR_027683 /// NR_027684 /// NR_027685 0006261 // DNA-dependent DNA replication // inferred from physical interaction /// 0006281 // DNA repair // inferred from physical interaction /// 0006310 // DNA recombination // inferred from physical interaction /// 0006606 // protein import into nucleus // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0032403 // protein complex binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216962_at M69039 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M69039.1 /DEF=Human pre-mRNA splicing factor SF2p32, complete sequence. /FEA=mRNA /DB_XREF=gi:338042 /UG=Hs.78614 complement component 1, q subcomponent binding protein M69039 RPA interacting protein RPAIN 84268 NM_001033002 /// NM_001160243 /// NM_001160244 /// NM_001160246 /// NM_001160266 /// NM_001160267 /// NM_032308 /// NR_027678 /// NR_027679 /// NR_027680 /// NR_027681 /// NR_027682 /// NR_027683 /// NR_027684 /// NR_027685 0006261 // DNA-dependent DNA replication // inferred from physical interaction /// 0006281 // DNA repair // inferred from physical interaction /// 0006310 // DNA recombination // inferred from physical interaction /// 0006606 // protein import into nucleus // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0032403 // protein complex binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216963_s_at AF279774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF279774.1 /DEF=Homo sapiens clone N4 NTera2D1 teratocarcinoma mRNA. /FEA=mRNA /DB_XREF=gi:11095815 /UG=Hs.79000 growth associated protein 43 AF279774 growth associated protein 43 GAP43 2596 NM_001130064 /// NM_002045 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0016198 // axon choice point recognition // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 216964_at AL162082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162082.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K1822 (from clone DKFZp434K1822); partial cds. /FEA=mRNA /GEN=DKFZp434K1822 /PROD=hypothetical protein /DB_XREF=gi:7328167 /UG=Hs.12064 ubiquitin specific protease 22 AL162082 ubiquitin specific peptidase 22 USP22 23326 NM_015276 /// XM_005256575 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216965_x_at AL139377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139377 /DEF=Human DNA sequence from clone RP11-251J8 on chromosome 13 Contains ESTs, STSs, GSSs and a CpG island. Contains two novel genes with two isoforms each and the KIAA0610 gene with two isoforms /FEA=mRNA_7 /DB_XREF=gi:10185469 /UG=Hs.118087 KIAA0610 protein AL139377 spastic paraplegia 20 (Troyer syndrome) SPG20 23111 NM_001142294 /// NM_001142295 /// NM_001142296 /// NM_015087 /// XM_005266313 /// XM_005266314 /// XM_005266315 /// XM_005266316 /// XM_005266317 0008219 // cell death // inferred from electronic annotation /// 0009838 // abscission // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0034389 // lipid particle organization // inferred from electronic annotation /// 0048698 // negative regulation of collateral sprouting in absence of injury // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0060612 // adipose tissue development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 216966_at J02963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J02963.1 /DEF=Human platelet glycoprotein IIb mRNA, 3 end. /FEA=mRNA /GEN=ITGA2B /DB_XREF=gi:190069 /UG=Hs.785 integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) J02963 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ITGA2B 3674 NM_000419 0002576 // platelet degranulation // traceable author statement /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0070527 // platelet aggregation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 216967_at AF279774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF279774.1 /DEF=Homo sapiens clone N4 NTera2D1 teratocarcinoma mRNA. /FEA=mRNA /DB_XREF=gi:11095815 /UG=Hs.79000 growth associated protein 43 AF279774 growth associated protein 43 GAP43 2596 NM_001130064 /// NM_002045 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0016198 // axon choice point recognition // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 216968_at Y18284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y18284.1 /DEF=Homo sapiens mRNA for mannose binding lectin-associated serine protease-2, incompletely spliced primary transcript, clone phl-8. /FEA=mRNA /GEN=MASP-2 /PROD=mannose binding lectin-associated serineprotease-2 related protein, MAp19 (19kDa) /DB_XREF=gi:5459320 /UG=Hs.119983 mannan-binding lectin serine protease 2 Y18284 mannan-binding lectin serine peptidase 2 MASP2 10747 NM_006610 /// NM_139208 0001867 // complement activation, lectin pathway // inferred from direct assay /// 0001867 // complement activation, lectin pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001855 // complement component C4b binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 216969_s_at AC002301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002301 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-328A3 /FEA=CDS_3 /DB_XREF=gi:2979567 /UG=Hs.119324 kinesin-like 4 AC002301 kinesin family member 22 KIF22 3835 NM_001256269 /// NM_001256270 /// NM_007317 /// XR_243280 0006281 // DNA repair // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // traceable author statement /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 216970_at AF090117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090117.1 /DEF=Homo sapiens regulator of G-protein signaling 7b (RGS7) mRNA, partial cds. /FEA=mRNA /GEN=RGS7 /PROD=regulator of G-protein signaling 7b /DB_XREF=gi:4959229 /UG=Hs.79348 regulator of G-protein signalling 7 AF090117 216971_s_at Z54367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z54367 /DEF=H.sapiens gene for plectin /FEA=CDS /DB_XREF=gi:1296661 /UG=Hs.79706 plectin 1, intermediate filament binding protein, 500kD Z54367 plectin PLEC 5339 NM_000445 /// NM_201378 /// NM_201379 /// NM_201380 /// NM_201381 /// NM_201382 /// NM_201383 /// NM_201384 /// XM_005250976 /// XM_005250977 /// XM_005250978 /// XM_005250979 /// XM_005250980 /// XM_005250981 /// XM_005250982 /// XM_005250983 /// XM_005250984 /// XM_006716588 /// XM_006716589 /// XM_006716590 /// XM_006716591 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046417 // chorismate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216972_at L13779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13779.1 /DEF=Homo sapiens (clone H16) sperm surface protein PH-20 mRNA sequence. /FEA=mRNA /DB_XREF=gi:291585 /UG=Hs.121494 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L13779 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) SPAM1 6677 NM_001174044 /// NM_001174045 /// NM_001174046 /// NM_003117 /// NM_153189 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0035036 // sperm-egg recognition // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 216973_s_at S49765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S49765.1 /DEF=homeobox gene human, mRNA Partial, 769 nt. /FEA=mRNA /GEN=homeobox gene /DB_XREF=gi:233572 /UG=Hs.819 homeo box B7 S49765 homeobox B7 HOXB7 3217 NM_004502 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 216974_at S80491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S80491.1 /DEF=stem cell factor {alternatively spliced} human, preimplantation embryos, blastocysts, mRNA Partial, 180 nt. /FEA=mRNA /GEN=stem cell factor, SCF /PROD=stem cell factor /DB_XREF=gi:1246099 /UG=Hs.123028 Stem cell factor {alternatively spliced} human, preimplantation embryos, blastocysts, mRNA Partial, 180 nt S80491 216975_x_at U51628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U51628.1 /DEF=Human MOP5 mRNA, partial cds. /FEA=mRNA /PROD=MOP5 /DB_XREF=gi:1695804 /UG=Hs.79564 neuronal PAS domain protein 1 U51628 neuronal PAS domain protein 1 NPAS1 4861 NM_002517 /// XM_006723231 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 216976_s_at X96588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X96588.1 /DEF=H.sapiens mRNA for H-RYK receptor tyrosine kinase. /FEA=mRNA /GEN=H-RYK /PROD=receptor tyrosine kinase /DB_XREF=gi:1296649 /UG=Hs.79350 RYK receptor-like tyrosine kinase X96588 receptor-like tyrosine kinase RYK 6259 NM_001005861 /// NM_002958 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from electronic annotation /// 0042813 // Wnt-activated receptor activity // inferred from electronic annotation 216977_x_at AJ130972 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ130972.1 /DEF=Homo sapiens mRNA for U2 snRNP-specific A protein, alternative transcript 3. /FEA=mRNA /PROD=U2 snRNP-specific A protein /DB_XREF=gi:3970728 /UG=Hs.80506 small nuclear ribonucleoprotein polypeptide A AJ130972 small nuclear ribonucleoprotein polypeptide A' SNRPA1 6627 NM_003090 /// XR_243213 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005686 // U2 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 216978_x_at U50277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U50277.1 /DEF=Human breast cancer suppressor element Ishmael Upper CP1 mRNA, partial cds. /FEA=mRNA /PROD=suppressor element Ishmael Upper CP1 /DB_XREF=gi:1224126 /UG=Hs.121485 Human breast cancer suppressor element Ishmael Upper CP1 mRNA, partial cds U50277 216979_at X89894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89894.1 /DEF=H.sapiens mRNA for nuclear receptor. /FEA=mRNA /PROD=nuclear receptor /DB_XREF=gi:1165104 /UG=Hs.80561 nuclear receptor subfamily 4, group A, member 3 X89894 nuclear receptor subfamily 4, group A, member 3 NR4A3 8013 NM_006981 /// NM_173198 /// NM_173199 /// NM_173200 /// XM_005252237 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060005 // vestibular reflex // inferred from electronic annotation /// 2000108 // positive regulation of leukocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216980_s_at X60502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X60502.1 /DEF=Human leukosialin cDNA-II. /FEA=mRNA /DB_XREF=gi:34345 /UG=Hs.80738 sialophorin (gpL115, leukosialin, CD43) X60502 sialophorin SPN 6693 NM_001030288 /// NM_003123 0001562 // response to protozoan // inferred from electronic annotation /// 0001808 // negative regulation of type IV hypersensitivity // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001931 // uropod // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement 216981_x_at X60502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X60502.1 /DEF=Human leukosialin cDNA-II. /FEA=mRNA /DB_XREF=gi:34345 /UG=Hs.80738 sialophorin (gpL115, leukosialin, CD43) X60502 leukosialin-like /// sialophorin LOC101929889 /// SPN 6693 /// 101929889 NM_001030288 /// NM_003123 /// XM_005276513 0001562 // response to protozoan // inferred from electronic annotation /// 0001808 // negative regulation of type IV hypersensitivity // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0001931 // uropod // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 216982_x_at U50277 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U50277.1 /DEF=Human breast cancer suppressor element Ishmael Upper CP1 mRNA, partial cds. /FEA=mRNA /PROD=suppressor element Ishmael Upper CP1 /DB_XREF=gi:1224126 /UG=Hs.121485 Human breast cancer suppressor element Ishmael Upper CP1 mRNA, partial cds U50277 216983_s_at BC002889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002889.1 /DEF=Homo sapiens, clone IMAGE:3941350, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3941350) /DB_XREF=gi:12804072 /UG=Hs.122605 Homo sapiens cDNA: FLJ22124 fis, clone HEP19352 BC002889 zinc finger protein 224 ZNF224 7767 NM_013398 /// XM_005259221 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 216984_x_at D84143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D84143.1 /DEF=Human immunoglobulin (mAb59) light chain V region mRNA, partial sequence. /FEA=mRNA /PROD=immunoglobulin light chain V-J region /DB_XREF=gi:1255613 /UG=Hs.121508 Human immunoglobulin (mAb59) light chain V region mRNA, partial sequence D84143 cytoskeleton associated protein 2 /// immunoglobulin lambda constant 1 (Mcg marker) /// /// immunoglobulin lambda joining 2 /// immunoglobulin lambda joining 3 /// immunoglobulin lambda joining 3 /// /// immunoglobulin lambda variable 1-44 /// /// immunoglobulin lambda variable cluster CKAP2 /// IGLC1 /// IGLJ2 /// IGLJ2 /// IGLJ3 /// IGLJ3 /// IGLJ3 /// IGLV1-44 /// IGLV2-14 /// IGLV@ 3537 /// 3546 /// 26586 /// 28823 /// 28831 NM_001098525 /// NM_001286686 /// NM_001286687 /// NM_018204 /// XM_005266343 /// XM_005266344 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 216985_s_at AJ002077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ002077.1 /DEF=Homo sapiens mRNA for syntaxin 3B, partial CDS. /FEA=mRNA /PROD=syntaxin 3B /DB_XREF=gi:2695734 /UG=Hs.82240 syntaxin 3A AJ002077 syntaxin 3 STX3 6809 NM_001178040 /// NM_004177 /// XM_005274195 /// XM_005274196 /// XM_005274198 /// XM_005274199 /// XM_005274200 /// XM_006718672 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0061025 // membrane fusion // inferred from electronic annotation 0005773 // vacuole // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0042581 // specific granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0050544 // arachidonic acid binding // inferred from sequence or structural similarity 216986_s_at D78261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D78261.1 /DEF=Human ICSAT transcription factor mRNA, partial cds, similar to mouse PipLSIRF ( IRF-4) sequence. /FEA=mRNA /PROD=ICSAT transcription factor /DB_XREF=gi:1183158 /UG=Hs.82132 interferon regulatory factor 4 D78261 interferon regulatory factor 4 IRF4 3662 NM_001195286 /// NM_002460 /// NR_036585 /// NR_046000 /// XM_006715090 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0018022 // peptidyl-lysine methylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0042110 // T cell activation // non-traceable author statement /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045082 // positive regulation of interleukin-10 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045368 // positive regulation of interleukin-13 biosynthetic process // inferred from direct assay /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from direct assay /// 0045622 // regulation of T-helper cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0072540 // T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0016279 // protein-lysine N-methyltransferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 216987_at D78261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D78261.1 /DEF=Human ICSAT transcription factor mRNA, partial cds, similar to mouse PipLSIRF ( IRF-4) sequence. /FEA=mRNA /PROD=ICSAT transcription factor /DB_XREF=gi:1183158 /UG=Hs.82132 interferon regulatory factor 4 D78261 interferon regulatory factor 4 IRF4 3662 NM_001195286 /// NM_002460 /// NR_036585 /// NR_046000 /// XM_006715090 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0018022 // peptidyl-lysine methylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0042110 // T cell activation // non-traceable author statement /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045082 // positive regulation of interleukin-10 biosynthetic process // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from direct assay /// 0045368 // positive regulation of interleukin-13 biosynthetic process // inferred from direct assay /// 0045404 // positive regulation of interleukin-4 biosynthetic process // inferred from direct assay /// 0045622 // regulation of T-helper cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0072540 // T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0016279 // protein-lysine N-methyltransferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 216988_s_at L48722 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L48722 /DEF=Homo sapiens (clone hh18) protein tyrosine phosphatase (ptp-IV1r) gene, 5 end of cds /FEA=CDS /DB_XREF=gi:1246237 /UG=Hs.82911 protein tyrosine phosphatase type IVA, member 2 L48722 protein tyrosine phosphatase type IVA, member 2 PTP4A2 8073 NM_001195100 /// NM_001195101 /// NM_003479 /// NM_080391 /// NM_080392 /// XM_005271229 /// XM_005271230 /// XM_005271231 /// XM_005271232 /// XM_006710927 /// XM_006710928 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 216989_at L13779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13779.1 /DEF=Homo sapiens (clone H16) sperm surface protein PH-20 mRNA sequence. /FEA=mRNA /DB_XREF=gi:291585 /UG=Hs.121494 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L13779 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) SPAM1 6677 NM_001174044 /// NM_001174045 /// NM_001174046 /// NM_003117 /// NM_153189 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0035036 // sperm-egg recognition // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 216990_at AF008655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF008655.1 /DEF=Homo sapiens GARS-AIRS-GART mRNA, partial cds. /FEA=mRNA /PROD=GARS-AIRS-GART /DB_XREF=gi:2459950 /UG=Hs.82285 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase AF008655 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART 2618 NM_000819 /// NM_001136005 /// NM_001136006 /// NM_175085 /// XM_005260941 /// XM_006723988 /// XM_006723989 /// XM_006723990 0003360 // brainstem development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004637 // phosphoribosylamine-glycine ligase activity // inferred from electronic annotation /// 0004641 // phosphoribosylformylglycinamidine cyclo-ligase activity // inferred from electronic annotation /// 0004644 // phosphoribosylglycinamide formyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 216991_at BC002889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002889.1 /DEF=Homo sapiens, clone IMAGE:3941350, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3941350) /DB_XREF=gi:12804072 /UG=Hs.122605 Homo sapiens cDNA: FLJ22124 fis, clone HEP19352 BC002889 AC084219.3 216992_s_at AJ236922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ236922.1 /DEF=Homo sapiens mRNA for metabotropic glutamate receptor 8c. /FEA=mRNA /GEN=mGluR8c /PROD=metabotropic glutamate receptor 8c /DB_XREF=gi:4456479 /UG=Hs.86204 glutamate receptor, metabotropic 8 AJ236922 glutamate receptor, metabotropic 8 GRM8 2918 NM_000845 /// NM_001127323 /// NR_028041 /// XM_006715938 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from mutant phenotype /// 0007601 // visual perception // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // not recorded 0001642 // group III metabotropic glutamate receptor activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from mutant phenotype /// 0008066 // glutamate receptor activity // inferred from mutant phenotype 216993_s_at U32169 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U32169 /DEF=Human pro-a2 chain of collagen type XI (COL11A2) gene, complete cds /FEA=mRNA_3 /DB_XREF=gi:1000744 /UG=Hs.121509 collagen, type XI, alpha 2 U32169 collagen, type XI, alpha 2 COL11A2 1302 NM_001163771 /// NM_080679 /// NM_080680 /// NM_080681 0001501 // skeletal system development // inferred from mutant phenotype /// 0001501 // skeletal system development // non-traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0060023 // soft palate development // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030020 // extracellular matrix structural constituent conferring tensile strength // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 216994_s_at L40992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L40992.1 /DEF=Homo sapiens (clone PEBP2aA1) core-binding factor, runt domain, alpha subunit 1 (CBFA1) mRNA, 3 end of cds. /FEA=mRNA /GEN=CBFA1 /PROD=core-binding factor, runt domain, alpha subunit1 /DB_XREF=gi:735897 /UG=Hs.121895 runt-related transcription factor 2 L40992 runt-related transcription factor 2 RUNX2 860 NM_001015051 /// NM_001024630 /// NM_001278478 /// NM_004348 /// NR_103532 /// NR_103533 /// XM_006715231 /// XM_006715232 /// XM_006715233 /// XM_006715234 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // traceable author statement /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001649 // osteoblast differentiation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 216995_x_at X06409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06409.1 /DEF=Human mRNA fragment for activated c-raf-1 (exons 8-17). /FEA=mRNA /DB_XREF=gi:30204 /UG=Hs.85181 v-raf-1 murine leukemia viral oncogene homolog 1 X06409 makorin ring finger protein 2 MKRN2 23609 NM_001271707 /// NM_014160 0000165 // MAPK cascade // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071550 // death-inducing signaling complex assembly // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from physical interaction /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 216996_s_at AK021557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021557.1 /DEF=Homo sapiens cDNA FLJ11495 fis, clone HEMBA1001950, highly similar to Homo sapiens mRNA for KIAA0971 protein. /FEA=mRNA /DB_XREF=gi:10432760 /UG=Hs.84429 KIAA0971 protein AK021557 FAST kinase domains 2 FASTKD2 22868 NM_001136193 /// NM_001136194 /// NM_014929 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 216997_x_at AL358975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL358975 /DEF=Human DNA sequence from clone RP11-375O18 on chromosome 9 Contains ESTs, STSs, GSSs and a CpG island. Contains the KIAA1261 gene for a novel transducin-like enhancer of split (TLE) and a putative novel gene /FEA=CDS_2 /DB_XREF=gi:11602548 /UG=Hs.83958 transducin-like enhancer of split 4, homolog of Drosophila E(sp1) AL358975 transducin-like enhancer of split 4 TLE4 7091 NM_001282748 /// NM_001282749 /// NM_001282753 /// NM_001282760 /// NM_007005 /// NR_104239 /// XM_005252167 /// XM_005252169 /// XM_005252173 /// XM_005252174 /// XM_005252175 /// XM_005252177 /// XM_006717264 /// XM_006717265 /// XM_006717266 /// XM_006717267 /// XM_006717268 /// XM_006717269 /// XM_006717270 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 216998_s_at AJ132821 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ132821.1 /DEF=Homo sapiens mRNA for tMDC II, isoform b. /FEA=mRNA /DB_XREF=gi:4468346 /UG=Hs.194768 a disintegrin and metalloproteinase domain 5 AJ132821 ADAM metallopeptidase domain 5, pseudogene ADAM5 255926 NM_001040073 /// NR_001448 0006508 // proteolysis // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 216999_at X97671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X97671.1 /DEF=H.sapiens mRNA for erythropoietin receptor. /FEA=mRNA /PROD=rearranged erythropoietin receptor Epo-R /DB_XREF=gi:1310666 /UG=Hs.89548 erythropoietin receptor X97671 erythropoietin receptor EPOR 2057 NM_000121 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0046697 // decidualization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 217000_at AL034348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034348 /DEF=Human DNA sequence from clone 84D21 on chromosome 6q15-16.3 Contains keratin pseudogene, STSs, GSSs and a CpG island /FEA=CDS /DB_XREF=gi:4775632 /UG=Hs.247875 Human DNA sequence from clone 84D21 on chromosome 6q15-16.3 Contains keratin pseudogene, STSs, GSSs and a CpG island AL034348 keratin 18 pseudogene 50 /// KRT18P50 /// KRT18P50 217001_x_at M29335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M29335.1 /DEF=Human MHC class II DO-alpha mRNA, partial cds. /FEA=mRNA /DB_XREF=gi:188002 /UG=Hs.123041 Human MHC class II DO-alpha mRNA, partial cds M29335 major histocompatibility complex, class II, DO alpha HLA-DOA 3111 NM_002119 /// XM_005249047 /// XM_005272804 /// XM_005274951 /// XM_005275106 /// XM_005275243 /// XM_005275383 /// XM_005275540 /// XM_006715076 /// XM_006725483 /// XM_006725697 /// XM_006725815 /// XM_006725906 /// XM_006725996 /// XM_006726086 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002587 // negative regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // traceable author statement 217002_s_at AJ003078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ003078.1 /DEF=Homo sapiens mRNA for 5-HT3 serotonin receptor (long isoform). /FEA=mRNA /PROD=serotonin receptor /DB_XREF=gi:3115221 /UG=Hs.2142 5-hydroxytryptamine (serotonin) receptor 3A AJ003078 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic HTR3A 3359 NM_000869 /// NM_001161772 /// NM_213621 /// NR_046363 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007586 // digestion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // non-traceable author statement /// 0005232 // serotonin-activated cation-selective channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation /// 0051378 // serotonin binding // inferred from direct assay 217003_s_at AJ132823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ132823.1 /DEF=Homo sapiens mRNA for tMDC II, isoform d. /FEA=mRNA /DB_XREF=gi:4468348 /UG=Hs.194768 a disintegrin and metalloproteinase domain 5 AJ132823 ADAM metallopeptidase domain 5, pseudogene ADAM5 255926 NM_001040073 /// NR_001448 0006508 // proteolysis // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 217004_s_at X13230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X13230.1 /DEF=Human mRNA for MCF.2 protein 3-end. /FEA=mRNA /DB_XREF=gi:34503 /UG=Hs.89543 MCF.2 cell line derived transforming sequence X13230 MCF.2 cell line derived transforming sequence MCF2 4168 NM_001099855 /// NM_001171876 /// NM_001171877 /// NM_001171878 /// NM_001171879 /// NM_005369 /// XM_005262413 /// XM_005262414 /// XM_006724757 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016358 // dendrite development // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 217005_at M28219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M28219.1 /DEF=Homo sapiens low density lipoprotein receptor (FH 10 mutant causing familial hypercholesterolemia) mRNA, 3 end. /FEA=mRNA /GEN=LDLR /PROD=low density lipoprotein receptor /DB_XREF=gi:619785 /UG=Hs.99940 Homo sapiens low density lipoprotein receptor (FH 10 mutant causing familial hypercholesterolemia) mRNA, 3 end M28219 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 217006_x_at U52428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U52428 /DEF=Human fatty acid synthase gene, partial cds /FEA=CDS_2 /DB_XREF=gi:1374810 /UG=Hs.83190 fatty acid synthase U52428 fatty acid synthase FASN 2194 NM_004104 0001649 // osteoblast differentiation // inferred from direct assay /// 0006084 // acetyl-CoA metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004312 // fatty acid synthase activity // traceable author statement /// 0004313 // [acyl-carrier-protein] S-acetyltransferase activity // inferred from electronic annotation /// 0004314 // [acyl-carrier-protein] S-malonyltransferase activity // inferred from electronic annotation /// 0004315 // 3-oxoacyl-[acyl-carrier-protein] synthase activity // inferred from electronic annotation /// 0004316 // 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity // inferred from electronic annotation /// 0004317 // 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0004319 // enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity // inferred from electronic annotation /// 0004320 // oleoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016295 // myristoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016296 // palmitoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016297 // acyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019171 // 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0031177 // phosphopantetheine binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047117 // enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity // inferred from electronic annotation /// 0047451 // 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from electronic annotation 217007_s_at AK000667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000667.1 /DEF=Homo sapiens cDNA FLJ20660 fis, clone KAT00151, highly similar to U41767 Human metargidin precursor mRNA. /FEA=mRNA /DB_XREF=gi:7020906 /UG=Hs.92208 a disintegrin and metalloproteinase domain 15 (metargidin) AK000667 ADAM metallopeptidase domain 15 ADAM15 8751 NM_001261464 /// NM_001261465 /// NM_001261466 /// NM_003815 /// NM_207191 /// NM_207194 /// NM_207195 /// NM_207196 /// NM_207197 /// NR_048577 /// NR_048578 /// NR_048579 0001525 // angiogenesis // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217008_s_at X94552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X94552.1 /DEF=H.sapiens mRNA for metabotropic glutamate receptor type 7. /FEA=mRNA /GEN=mGluR7 /PROD=glutamate receptor /DB_XREF=gi:1370110 /UG=Hs.83407 glutamate receptor, metabotropic 7 X94552 glutamate receptor, metabotropic 7 /// uncharacterized LOC100996542 GRM7 /// LOC100996542 2917 /// 100996542 NM_000844 /// NM_181874 /// NM_181875 /// XM_005265095 /// XR_159402 0001661 // conditioned taste aversion // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007196 // adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // inferred from direct assay /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007614 // short-term memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from direct assay /// 0031279 // regulation of cyclase activity // inferred from direct assay /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0050877 // neurological system process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from direct assay /// 0032279 // asymmetric synapse // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // not recorded /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048786 // presynaptic active zone // inferred from sequence or structural similarity 0001642 // group III metabotropic glutamate receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // not recorded /// 0005509 // calcium ion binding // inferred from direct assay /// 0008066 // glutamate receptor activity // inferred from direct assay /// 0010855 // adenylate cyclase inhibitor activity // inferred from direct assay /// 0016595 // glutamate binding // inferred from direct assay /// 0030165 // PDZ domain binding // non-traceable author statement /// 0070905 // serine binding // inferred from direct assay 217009_at AL121974 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121974 /DEF=Human DNA sequence from clone RP3-417L20 on chromosome 6p12-21.3. Contains the 5 end of the gene for cysteine-rich secretory protein 3 (CRISP-3, SGP28), the PGK2 gene for phosphoglycerate kinase 2, STSs and GSSs /FEA=CDS /DB_XREF=gi:9828129 /UG=Hs.78771 phosphoglycerate kinase 1 AL121974 phosphoglycerate kinase 2 PGK2 5232 NM_138733 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // non-traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0004618 // phosphoglycerate kinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 217010_s_at AF277724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF277724.1 /DEF=Homo sapiens cell division cycle 25C splice variant 3 (CDC25C) mRNA, partial cds. /FEA=mRNA /GEN=CDC25C /PROD=cell division cycle 25C splice variant 3 /DB_XREF=gi:11934924 /UG=Hs.656 cell division cycle 25C AF277724 cell division cycle 25C CDC25C 995 NM_001287582 /// NM_001287583 /// NM_001790 /// NM_022809 /// XM_005272145 /// XM_005272146 /// XM_006714739 /// XM_006714740 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from genetic interaction /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 217011_at L11239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L11239 /DEF=Homo sapiens homeobox protein (HOX) gene, 3 end /FEA=mRNA /DB_XREF=gi:306876 /UG=Hs.36993 gastrulation brain homeo box 1 L11239 gastrulation brain homeobox 1 GBX1 2636 NM_001098834 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0097374 // sensory neuron axon guidance // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217012_at AL080233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080233.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L111 (from clone DKFZp586L111). /FEA=mRNA /DB_XREF=gi:5262726 /UG=Hs.326580 Homo sapiens mRNA; cDNA DKFZp586L111 (from clone DKFZp586L111) AL080233 217013_at AC004522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004522 /DEF=Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 /FEA=CDS_1 /DB_XREF=gi:3006227 /UG=Hs.307354 Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 AC004522 alpha-2-glycoprotein 1, zinc-binding pseudogene 1 AZGP1P1 646282 NR_036679 217014_s_at AC004522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004522 /DEF=Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 /FEA=CDS_1 /DB_XREF=gi:3006227 /UG=Hs.307354 Homo sapiens PAC clone RP4-604G5 from 7q22-q31.1 AC004522 alpha-2-glycoprotein 1, zinc-binding /// alpha-2-glycoprotein 1, zinc-binding pseudogene 1 AZGP1 /// AZGP1P1 563 /// 646282 NM_001185 /// NR_036679 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0019882 // antigen processing and presentation // not recorded /// 0071806 // protein transmembrane transport // non-traceable author statement /// 0090501 // RNA phosphodiester bond hydrolysis // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // not recorded /// 0004540 // ribonuclease activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008320 // protein transmembrane transporter activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from electronic annotation 217015_at AL390237 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390237 /DEF=Human DNA sequence from clone RP11-278J20 on chromosome 6. Contains ESTs, STSs and GSSs. Contains an RBBP4 (retinoblastoma-binding protein 4) pseudogene and a KIAA0797 pseudogene /FEA=CDS_1 /DB_XREF=gi:10120117 /UG=Hs.307104 Human DNA sequence from clone RP11-278J20 on chromosome 6. Contains ESTs, STSs and GSSs. Contains an RBBP4 (retinoblastoma-binding protein 4) pseudogene and a KIAA0797 pseudogene AL390237 retinoblastoma binding protein 4 pseudogene 4 /// RBBP4P4 /// RBBP4P4 217016_x_at AK026825 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026825.1 /DEF=Homo sapiens cDNA: FLJ23172 fis, clone LNG10005. /FEA=mRNA /DB_XREF=gi:10439771 /UG=Hs.306885 Homo sapiens cDNA: FLJ23172 fis, clone LNG10005 AK026825 transmembrane protein 212 TMEM212 389177 NM_001164436 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217017_at AK024945 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024945.1 /DEF=Homo sapiens cDNA: FLJ21292 fis, clone COL01969. /FEA=mRNA /DB_XREF=gi:10437367 /UG=Hs.306732 Homo sapiens cDNA: FLJ21292 fis, clone COL01969 AK024945 oxysterol binding protein-like 10 OSBPL10 114884 NM_001174060 /// NM_017784 /// XM_005264843 /// XM_005264844 /// XM_005264845 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 217018_at AK000293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000293.1 /DEF=Homo sapiens cDNA FLJ20286 fis, clone HEP04358. /FEA=mRNA /DB_XREF=gi:7020278 /UG=Hs.306391 Homo sapiens cDNA FLJ20286 fis, clone HEP04358 AK000293 217019_at AL137162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137162 /DEF=Human DNA sequence from clone RP5-843L14 on chromosome 20. Contains ESTs, STSs and GSSs. Contains a novel gene and the 5 part of a gene for a novel protein similar to X-linked ribosomal protein 4 (RPS4X) /FEA=CDS /DB_XREF=gi:11190480 /UG=Hs.302114 Human DNA sequence from clone RP5-843L14 on chromosome 20. Contains ESTs, STSs and GSSs. Contains a novel gene and the 5 part of a gene for a novel protein similar to X-linked ribosomal protein 4 (RPS4X) AL137162 ribosomal protein S4X pseudogene 3 /// RPS4XP3 /// RPS4XP3 217020_at X04014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X04014 /DEF=Homo sapiens DNA for HBV integration sites /FEA=CDS /DB_XREF=gi:32037 /UG=Hs.306280 Homo sapiens DNA for HBV integration sites X04014 retinoic acid receptor, beta RARB 5915 NM_000965 /// NM_001290216 /// NM_001290217 /// NM_001290266 /// NM_001290276 /// NM_001290277 /// NM_001290300 /// NM_016152 /// NR_110892 /// NR_110893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021756 // striatum development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation 217021_at AL353132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353132 /DEF=Human DNA sequence from clone RP11-189G24 on chromosome 20. Contains a cytochrome B5 (CYB5) pseudogene and GSSs /FEA=CDS /DB_XREF=gi:11121023 /UG=Hs.302116 Human DNA sequence from clone RP11-189G24 on chromosome 20. Contains a cytochrome B5 (CYB5) pseudogene and GSSs AL353132 cytochrome b5 type A (microsomal) CYB5A 1528 NM_001190807 /// NM_001914 /// NM_148923 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217022_s_at S55735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S55735.1 /DEF=Homo sapiens immunoglobulin A1-A2 lambda hybrid GAU heavy chain mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin A1-A2 lambda hybrid GAU heavychain /DB_XREF=gi:265703 /UG=Hs.293441 VPS28 protein S55735 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) IGH /// IGHA1 /// IGHA2 3492 /// 3493 /// 3494 0001895 // retina homeostasis // inferred from expression pattern /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0034987 // immunoglobulin receptor binding // inferred from direct assay 217023_x_at AF099143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF099143 /DEF=Homo sapiens mast cell tryptase beta III gene, complete cds /FEA=mRNA /DB_XREF=gi:4336616 /UG=Hs.294158 tryptase beta 2 AF099143 tryptase alpha/beta 1 /// tryptase beta 2 (gene/pseudogene) TPSAB1 /// TPSB2 7177 /// 64499 NM_003294 /// NM_024164 0006508 // proteolysis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 217024_x_at AC004832 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004832 /DEF=Homo sapiens PAC clone RP4-539M6 from 22 /FEA=CDS_3 /DB_XREF=gi:6624129 /UG=Hs.287353 Homo sapiens PAC clone RP4-539M6 from 22 AC004832 signal-regulatory protein alpha pseudogene 1 /// SIRPAP1 /// SIRPAP1 217025_s_at AL110225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110225.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D064 (from clone DKFZp434D064); partial cds. /FEA=mRNA /GEN=DKFZp434D064 /PROD=hypothetical protein /DB_XREF=gi:5817161 /UG=Hs.89434 drebrin 1 AL110225 drebrin 1 DBN1 1627 NM_004395 /// NM_080881 /// XM_005265827 /// XM_005265828 /// XM_005265829 /// XM_006714826 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032507 // maintenance of protein location in cell // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // non-traceable author statement /// 0048699 // generation of neurons // inferred from electronic annotation /// 0050773 // regulation of dendrite development // non-traceable author statement /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // non-traceable author statement /// 0042641 // actomyosin // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from sequence or structural similarity 217026_at M96936 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M96936 /DEF=Homo sapiens cystic fibrosis transmembrane conductance regulator (CFTR) gene, exons 23, 24a, and 24 /FEA=mRNA /DB_XREF=gi:180293 /UG=Hs.283899 Homo sapiens cystic fibrosis transmembrane conductance regulator (CFTR) gene, exons 23, 24a, and 24 M96936 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) CFTR 1080 NM_000492 /// XM_006715842 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006833 // water transport // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // inferred from electronic annotation /// 0015705 // iodide transport // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // non-traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement /// 1902943 // positive regulation of voltage-gated chloride channel activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031205 // endoplasmic reticulum Sec complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005224 // ATP-binding and phosphorylation-dependent chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from direct assay /// 0005260 // channel-conductance-controlling ATPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 217027_x_at AC004941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004941 /DEF=Homo sapiens PAC clone RP5-979P20 from 7q33-q35 /FEA=CDS /DB_XREF=gi:4454517 /UG=Hs.283758 Homo sapiens PAC clone RP5-979P20 from 7q33-q35 AC004941 AC004941.5 217028_at AJ224869 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ224869 /DEF=Homo sapiens CXCR4 gene encoding receptor CXCR4 /FEA=mRNA /DB_XREF=gi:3059119 /UG=Hs.89414 chemokine (C-X-C motif), receptor 4 (fusin) AJ224869 chemokine (C-X-C motif) receptor 4 CXCR4 7852 NM_001008540 /// NM_003467 0000187 // activation of MAPK activity // traceable author statement /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030260 // entry into host cell // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042119 // neutrophil activation // inferred from electronic annotation /// 0043217 // myelin maintenance // inferred from sequence or structural similarity /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // non-traceable author statement /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // non-traceable author statement /// 0019955 // cytokine binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032027 // myosin light chain binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 217029_at AL049301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049301.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073). /FEA=mRNA /DB_XREF=gi:4500067 /UG=Hs.278577 Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) AL049301 217030_at AL137475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137475.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F0723 (from clone DKFZp434F0723). /FEA=mRNA /DB_XREF=gi:6808086 /UG=Hs.274578 Homo sapiens mRNA; cDNA DKFZp434F0723 (from clone DKFZp434F0723) AL137475 uncharacterized LOC101929550 LOC101929550 101929550 XR_247158 /// XR_250340 /// XR_252405 217031_at Y19209 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y19209 /DEF=Homo sapiens hHb4 gene for hair keratin, exons 1 to 10 /FEA=mRNA /DB_XREF=gi:7161768 /UG=Hs.272336 Homo sapiens hHb4 gene for hair keratin, exons 1 to 10 Y19209 keratin 84 KRT84 3890 NM_033045 0001942 // hair follicle development // non-traceable author statement /// 0035878 // nail development // non-traceable author statement /// 0045616 // regulation of keratinocyte differentiation // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0030280 // structural constituent of epidermis // inferred from electronic annotation 217032_at AL078621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078621 /DEF=Human DNA sequence from clone RP11-395L14. Contains (part of) up to six novel genes or pseudogenes, the gene for a novel forkhead protein similar to FOXD4 (forkhead box D4, FREAC5), the gene for a novel phosphoglucomutase like protein, a pseudogen... /FEA=CDS_1 /DB_XREF=gi:6013067 /UG=Hs.272339 Human DNA sequence from clone RP11-395L14. Contains (part of) up to six novel genes or pseudogenes, the gene for a novel forkhead protein similar to FOXD4 (forkhead box D4, FREAC5), the gene for a novel phosphoglucomutase like protein, a pseudogene simila AL078621 forkhead box D4 /// forkhead box D4-like 1 FOXD4 /// FOXD4L1 2298 /// 200350 NM_012184 /// NM_207305 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001755 // neural crest cell migration // not recorded /// 0001822 // kidney development // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007389 // pattern specification process // not recorded /// 0007422 // peripheral nervous system development // not recorded /// 0009790 // embryo development // /// 0030318 // melanocyte differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded /// 0048484 // enteric nervous system development // not recorded /// 0048485 // sympathetic nervous system development // not recorded /// 0048846 // axon extension involved in axon guidance // not recorded /// 0048937 // lateral line nerve glial cell development // not recorded /// 0050935 // iridophore differentiation // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051216 // cartilage development // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217033_x_at S76475 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S76475.1 /DEF=trkC human, brain, mRNA, 2715 nt. /FEA=mRNA /GEN=trkC /DB_XREF=gi:913721 /UG=Hs.26776 neurotrophic tyrosine kinase, receptor, type 3 S76475 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 217034_at AF103529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103529.1 /DEF=Homo sapiens isolate donor N clone N88K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4378387 /UG=Hs.247910 Homo sapiens isolate donor N clone N88K immunoglobulin kappa light chain variable region mRNA, partial cds AF103529 uncharacterized LOC101928457 LOC101928457 101928457 XR_245045 /// XR_431452 217035_at X95660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95660.1 /DEF=H.sapiens mRNA for variable region of IgA (VH4 family). /FEA=mRNA /PROD=variable region of IgA /DB_XREF=gi:1261909 /UG=Hs.248023 H.sapiens mRNA for variable region of IgA (VH4 family) X95660 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement 217036_at AF103530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103530.1 /DEF=Homo sapiens isolate donor N clone N8K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4378389 /UG=Hs.247911 Homo sapiens isolate donor N clone N8K immunoglobulin kappa light chain variable region mRNA, partial cds AF103530 217037_at S83374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S83374.1 /DEF=glutamate transporter II variant BHBGT IIB {5 region} human, brain and spinal cord, mRNA Partial Mutant, 129 nt. /FEA=mRNA /DB_XREF=gi:1911635 /UG=Hs.123079 Glutamate transporter II variant BHBGT IIB {5 region} human, brain and spinal cord, mRNA Partial Mutant, 129 nt S83374 217038_at AL035067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035067 /DEF=Human DNA sequence from clone 170F5 on chromosome Xq22.3-24. Contains an HMG1 (high-mobility group (nonhistone chromosomal) protein 1) pseudogene and ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:4455454 /UG=Hs.247844 Human DNA sequence from clone 170F5 on chromosome Xq22.3-24. Contains an HMG1 (high-mobility group (nonhistone chromosomal) protein 1) pseudogene and ESTs, STSs and GSSs AL035067 high mobility group box 1 pseudogene 12 /// HMGB1P12 /// HMGB1P12 217039_x_at AB016195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB016195 /DEF=Homo sapiens ELK1 pseudogene (ELK2) and immunoglobulin heavy chain gamma pseudogene (IGHGP) /FEA=CDS /DB_XREF=gi:4140034 /UG=Hs.247775 Homo sapiens ELK1 pseudogene (ELK2) and immunoglobulin heavy chain gamma pseudogene (IGHGP) AB016195 ELK2A, member of ETS oncogene family, pseudogene ELK2AP 2003 NR_046211 217040_x_at AB025355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB025355 /DEF=Homo sapiens gene for SOX20, partial cds /FEA=CDS /DB_XREF=gi:5103146 /UG=Hs.247687 Homo sapiens gene for SOX20, partial cds AB025355 SRY (sex determining region Y)-box 15 SOX15 6665 NM_006942 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0014718 // positive regulation of satellite cell activation involved in skeletal muscle regeneration // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045843 // negative regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0070318 // positive regulation of G0 to G1 transition // inferred from sequence or structural similarity /// 2000288 // positive regulation of myoblast proliferation // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217041_at AL162057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162057.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761N0524 (from clone DKFZp761N0524). /FEA=mRNA /DB_XREF=gi:7328105 /UG=Hs.91622 neuronal pentraxin receptor AL162057 neuronal pentraxin receptor NPTXR 23467 NM_014293 /// NM_058178 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 217042_at AL096716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096716.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564M1462 (from clone DKFZp564M1462); partial cds. /FEA=mRNA /GEN=DKFZp564M1462 /PROD=hypothetical protein /DB_XREF=gi:5419850 /UG=Hs.226007 DKFZP564M1462 protein AL096716 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) RDH11 51109 NM_001252650 /// NM_016026 0001523 // retinoid metabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016062 // adaptation of rhodopsin mediated signaling // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from sequence or structural similarity /// 0042574 // retinal metabolic process // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from direct assay 217043_s_at U95822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U95822.1 /DEF=Human putative transmembrane GTPase mRNA, partial cds. /FEA=mRNA /GEN=fzo /PROD=putative transmembrane GTPase /DB_XREF=gi:2252803 /UG=Hs.197877 hypothetical protein FLJ20693 U95822 mitofusin 1 MFN1 55669 NM_017927 /// NM_033540 /// XM_005247595 /// XM_005247596 0006184 // GTP catabolic process // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from direct assay /// 0008053 // mitochondrial fusion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217044_s_at BC004298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004298.1 /DEF=Homo sapiens, clone IMAGE:3622874, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3622874) /DB_XREF=gi:13279160 /UG=Hs.198037 KIAA0599 protein BC004298 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 PLEKHG3 26030 NM_015549 /// XM_005267511 /// XM_005267512 /// XM_005267513 /// XM_006720106 /// XM_006720107 /// XM_006720108 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 217045_x_at AL136967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136967 /DEF=Human DNA sequence from clone RP1-149M18 on chromosome 6 Contains ESTs, STSs, GSSs and CpG islands. Contains the natural killer cell p44 related gene (NKp44RG) with three isoforms /FEA=mRNA_3 /DB_XREF=gi:9501164 /UG=Hs.194721 lymphocyte antigen 95 (activating NK-receptor ; NK-p44) AL136967 natural cytotoxicity triggering receptor 2 NCR2 9436 NM_001199509 /// NM_001199510 /// NM_004828 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217046_s_at AJ133822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ133822.1 /DEF=Homo sapiens mRNA for receptor for Advanced Glycation End Product, secreted isoform (RAGEsec gene). /FEA=mRNA /GEN=RAGEsec /PROD=receptor for Advanced Glycation End Products /DB_XREF=gi:4877290 /UG=Hs.184 advanced glycosylation end product-specific receptor AJ133822 advanced glycosylation end product-specific receptor AGER 177 NM_001136 /// NM_001206929 /// NM_001206932 /// NM_001206934 /// NM_001206936 /// NM_001206940 /// NM_001206954 /// NM_001206966 /// NM_172197 /// NR_038190 0006954 // inflammatory response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0031175 // neuron projection development // inferred from genetic interaction /// 0045087 // innate immune response // traceable author statement /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction 217047_s_at AK027138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027138.1 /DEF=Homo sapiens cDNA: FLJ23485 fis, clone KAIA05211. /FEA=mRNA /DB_XREF=gi:10440190 /UG=Hs.177664 KIAA0914 gene product AK027138 family with sequence similarity 13, member A FAM13A 10144 NM_001015045 /// NM_001265578 /// NM_001265579 /// NM_001265580 /// NM_014883 /// XM_005262681 /// XM_005262682 /// XM_005262683 /// XM_005262684 /// XM_005262685 /// XM_006714057 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 217048_at Y09846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09846 /DEF=H.sapiens shc pseudogene, p66 isoform /FEA=mRNA /DB_XREF=gi:1834516 /UG=Hs.166089 SHC (Src homology 2 domain-containing) transforming protein 1 pseudogene 1 Y09846 SHC (Src homology 2 domain containing) transforming protein 1 pseudogene 1 /// SHC1P1 /// SHC1P1 217049_x_at AJ276803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276803.1 /DEF=Homo sapiens mRNA for protocadherin (PCDHY gene). /FEA=mRNA /GEN=PCDHY /PROD=protocadherin /DB_XREF=gi:10803410 /UG=Hs.159156 protocadherin 11 AJ276803 protocadherin 11 X-linked /// protocadherin 11 Y-linked PCDH11X /// PCDH11Y 27328 /// 83259 NM_001168360 /// NM_001168361 /// NM_001168362 /// NM_001168363 /// NM_001278619 /// NM_014522 /// NM_032967 /// NM_032968 /// NM_032969 /// NM_032971 /// NM_032972 /// NM_032973 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 217050_at L22650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L22650.1 /DEF=Human early lymphoid activation protein (EPAG) mRNA sequence. /FEA=mRNA /PROD=early lymphoid activation protein /DB_XREF=gi:468321 /UG=Hs.157431 early lymphoid activation protein L22650 DIAPH2 antisense RNA 1 DIAPH2-AS1 10824 XM_926826 0007165 // signal transduction // non-traceable author statement 0004871 // signal transducer activity // non-traceable author statement 217051_s_at AF257501 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF257501.1 /DEF=Homo sapiens SYTSSX4v fusion protein (SSXTSSX4v fusion) mRNA, partial cds. /FEA=mRNA /GEN=SSXTSSX4v fusion /PROD=SYTSSX4v fusion protein /DB_XREF=gi:11127696 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome AF257501 217052_x_at AK024108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024108.1 /DEF=Homo sapiens cDNA FLJ14046 fis, clone HEMBA1006461. /FEA=mRNA /DB_XREF=gi:10436406 /UG=Hs.142677 Homo sapiens cDNA FLJ14046 fis, clone HEMBA1006461 AK024108 217053_x_at X87175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X87175.1 /DEF=H.sapiens mRNA for ER81 transcription factor. /FEA=CDS /GEN=ER81 /PROD=ER81 protein /DB_XREF=gi:1045060 /UG=Hs.89566 ets variant gene 1 X87175 ets variant 1 ETV1 2115 NM_001163147 /// NM_001163148 /// NM_001163149 /// NM_001163150 /// NM_001163151 /// NM_001163152 /// NM_004956 /// NR_120445 /// XM_005249635 /// XM_005249636 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // traceable author statement 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217054_at AF007194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007194.1 /DEF=Homo sapiens mucin (MUC3) mRNA, partial cds. /FEA=mRNA /GEN=MUC3 /PROD=mucin /DB_XREF=gi:2853300 /UG=Hs.129782 mucin 3A, intestinal AF007194 Homo sapiens cDNA FLJ39484 fis, clone PROST2014925. /// AK096803 /// RP11-395B7.2 217055_x_at S83374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S83374.1 /DEF=glutamate transporter II variant BHBGT IIB {5 region} human, brain and spinal cord, mRNA Partial Mutant, 129 nt. /FEA=mRNA /DB_XREF=gi:1911635 /UG=Hs.123079 Glutamate transporter II variant BHBGT IIB {5 region} human, brain and spinal cord, mRNA Partial Mutant, 129 nt S83374 217056_at X61070 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61070.1 /DEF=Human mRNA for T cell receptor, clone IGRA15. /FEA=mRNA /PROD=T cell receptor /DB_XREF=gi:33508 /UG=Hs.121492 Human mRNA for T cell receptor, clone IGRA15 X61070 Homo sapiens mRNA for T cell receptor alpha variable 14, partial cds, clone: SEB 416. /// SubName: Full=HADV36S1; Flags: Fragment; /// Homo sapiens mRNA for T cell receptor alpha variable 24, partial cds, clone: SEB 118. /// Homo sapiens mRNA for T cell receptor alpha variable 36, partial cds, clone: SEB 31. /// Homo sapiens mRNA for T cell receptor alpha variable 26, partial cds, clone: SEB 84. /// RecName: Full=T-cell receptor alpha chain C region; /// T cell receptor alpha joining 20 /// /// /// T cell receptor alpha variable 36/delta variable 7 /// YME1-like 1 ATPase AV8S2A1N1T /// hADV36S1 /// TCR-alpha /// TCR-alpha /// TCRA /// TRAC /// TRAJ20 /// TRAJ20 /// TRAV36DV7 /// TRAV36DV7 /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217057_s_at AF107846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF107846 /DEF=Homo sapiens neuroendocrine-specific Golgi protein p55 (XLalphas) gene, exon XL2 and complete cds /FEA=mRNA /DB_XREF=gi:4206779 /UG=Hs.113368 neuroendocrine secretory protein 55 AF107846 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 217058_at AF107846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF107846 /DEF=Homo sapiens neuroendocrine-specific Golgi protein p55 (XLalphas) gene, exon XL2 and complete cds /FEA=mRNA /DB_XREF=gi:4206779 /UG=Hs.113368 neuroendocrine secretory protein 55 AF107846 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 217059_at L13283 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L13283.1 /DEF=Homo sapiens (clone MG2-5-12) mucin (MG2) mRNA, complete polyA site. /FEA=mRNA /DB_XREF=gi:292518 /UG=Hs.103944 Homo sapiens (clone MG2-5-12) mucin (MG2) mRNA, complete polyA site L13283 mucin 7, secreted MUC7 4589 NM_001145006 /// NM_001145007 /// NM_152291 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217060_at U03115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U03115 /DEF=Human V beta T-cell receptor (TCRBV) gene locus /FEA=mRNA /DB_XREF=gi:467918 /UG=Hs.103945 Human V beta T-cell receptor (TCRBV) gene locus U03115 217061_s_at AC004857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004857 /DEF=Homo sapiens PAC clone RP4-685A2 from 7p21-p22 /FEA=CDS /DB_XREF=gi:3694665 /UG=Hs.89566 ets variant gene 1 AC004857 ets variant 1 ETV1 2115 NM_001163147 /// NM_001163148 /// NM_001163149 /// NM_001163150 /// NM_001163151 /// NM_001163152 /// NM_004956 /// NR_120445 /// XM_005249635 /// XM_005249636 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // traceable author statement 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217062_at M87313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M87313.1 /DEF=Homo sapiens myotonin protein kinase (DM) mRNA. /FEA=mRNA /DB_XREF=gi:189038 /UG=Hs.898 dystrophia myotonica-protein kinase M87313 AC074212.6 217063_x_at X61079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61079.1 /DEF=Human mRNA for T cell receptor, clone IGRA24. /FEA=mRNA /PROD=T cell receptor /DB_XREF=gi:33521 /UG=Hs.123062 Human mRNA for T cell receptor, clone IGRA24 X61079 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217065_at X61079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X61079.1 /DEF=Human mRNA for T cell receptor, clone IGRA24. /FEA=mRNA /PROD=T cell receptor /DB_XREF=gi:33521 /UG=Hs.123062 Human mRNA for T cell receptor, clone IGRA24 X61079 217066_s_at M87313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M87313.1 /DEF=Homo sapiens myotonin protein kinase (DM) mRNA. /FEA=mRNA /DB_XREF=gi:189038 /UG=Hs.898 dystrophia myotonica-protein kinase M87313 dystrophia myotonica-protein kinase DMPK 1760 NM_001081560 /// NM_001081562 /// NM_001081563 /// NM_001288764 /// NM_001288765 /// NM_001288766 /// NM_004409 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from mutant phenotype /// 0008016 // regulation of heart contraction // inferred from direct assay /// 0010657 // muscle cell apoptotic process // inferred from direct assay /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0014722 // regulation of skeletal muscle contraction by calcium ion signaling // inferred from electronic annotation /// 0014853 // regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017020 // myosin phosphatase regulator activity // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217067_s_at U34037 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U34037 /DEF=Human dentin matrix acidic phosphoprotein (DMP1) gene, partial cds /FEA=CDS /DB_XREF=gi:1143199 /UG=Hs.93465 dentin matrix acidic phosphoprotein U34037 dentin matrix acidic phosphoprotein 1 DMP1 1758 NM_001079911 /// NM_004407 0001503 // ossification // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation 217068_at U82303 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82303.1 /DEF=Homo sapiens unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1938329 /UG=Hs.123080 Homo sapiens unknown protein mRNA, partial cds U82303 217069_at AF105279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF105279.1 /DEF=Homo sapiens myeloidlymphoid leukemia 2 (MLL2) mRNA, alternatively spliced, partial cds. /FEA=mRNA /GEN=MLL2 /PROD=myeloidlymphoid leukemia 2 /DB_XREF=gi:4588364 /UG=Hs.92236 KIAA0304 gene product AF105279 lysine (K)-specific methyltransferase 2B KMT2B 9757 NM_014727 /// XM_006723513 /// XM_006723514 /// XM_006723515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009994 // oocyte differentiation // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // non-traceable author statement /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217070_at AJ249275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ249275 /DEF=Homo sapiens partial MTHFR gene for methylenetetrahydrofolate reductase /FEA=CDS /DB_XREF=gi:7271187 /UG=Hs.214142 5,10-methylenetetrahydrofolate reductase (NADPH) AJ249275 methylenetetrahydrofolate reductase (NAD(P)H) MTHFR 4524 NM_005957 /// XM_005263458 /// XM_005263460 /// XM_005263461 /// XM_005263462 /// XM_005263463 0001666 // response to hypoxia // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006555 // methionine metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0033274 // response to vitamin B2 // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004489 // methylenetetrahydrofolate reductase (NAD(P)H) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 217071_s_at AJ249275 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ249275 /DEF=Homo sapiens partial MTHFR gene for methylenetetrahydrofolate reductase /FEA=CDS /DB_XREF=gi:7271187 /UG=Hs.214142 5,10-methylenetetrahydrofolate reductase (NADPH) AJ249275 methylenetetrahydrofolate reductase (NAD(P)H) MTHFR 4524 NM_005957 /// XM_005263458 /// XM_005263460 /// XM_005263461 /// XM_005263462 /// XM_005263463 0001666 // response to hypoxia // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006555 // methionine metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0033274 // response to vitamin B2 // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046500 // S-adenosylmethionine metabolic process // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004489 // methylenetetrahydrofolate reductase (NAD(P)H) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 217072_at AF161346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161346.1 /DEF=Homo sapiens HSPC083 mRNA, partial cds. /FEA=mRNA /PROD=HSPC083 /DB_XREF=gi:6841105 /UG=Hs.9688 leukocyte membrane antigen AF161346 CD300a molecule CD300A 11314 NM_001256841 /// NM_007261 /// XM_005256990 /// XM_005256991 /// XM_005256992 /// XM_006721656 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0033007 // negative regulation of mast cell activation involved in immune response // inferred from direct assay /// 0043305 // negative regulation of mast cell degranulation // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050856 // regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050859 // negative regulation of B cell receptor signaling pathway // inferred from direct assay /// 0051134 // negative regulation of NK T cell activation // inferred from direct assay /// 0060101 // negative regulation of phagocytosis, engulfment // inferred from mutant phenotype /// 1902564 // negative regulation of neutrophil activation // inferred from direct assay /// 1902567 // negative regulation of eosinophil activation // inferred from direct assay /// 1902569 // negative regulation of activation of JAK2 kinase activity // inferred from direct assay /// 2000417 // negative regulation of eosinophil migration // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0038023 // signaling receptor activity // inferred from direct assay 217073_x_at X02162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X02162.1 /DEF=Human mRNA for apolipoprotein AI (apo AI)=. /FEA=mRNA /PROD=preproapolipoprotein AI /DB_XREF=gi:28771 /UG=Hs.93194 apolipoprotein A-I X02162 apolipoprotein A-I APOA1 335 NM_000039 /// XM_005271539 /// XM_005271540 0001523 // retinoid metabolic process // traceable author statement /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0019915 // lipid storage // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from direct assay /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred by curator /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred by curator /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050713 // negative regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051345 // positive regulation of hydrolase activity // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055091 // phospholipid homeostasis // inferred from direct assay /// 0060192 // negative regulation of lipase activity // inferred from electronic annotation /// 0060354 // negative regulation of cell adhesion molecule production // inferred from direct assay /// 0060761 // negative regulation of response to cytokine stimulus // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from direct assay /// 0070508 // cholesterol import // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005548 // phospholipid transporter activity // inferred from electronic annotation /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0034190 // apolipoprotein receptor binding // inferred from physical interaction /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from electronic annotation /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070653 // high-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 217074_at AK025938 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025938.1 /DEF=Homo sapiens cDNA: FLJ22285 fis, clone HRC03956. /FEA=mRNA /DB_XREF=gi:10438607 /UG=Hs.92374 hypothetical protein AK025938 spermine oxidase SMOX 54498 NM_001270691 /// NM_175839 /// NM_175840 /// NM_175841 /// NM_175842 /// XM_006723578 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046208 // spermine catabolic process // inferred from direct assay /// 0046208 // spermine catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046592 // polyamine oxidase activity // inferred from direct assay /// 0052894 // norspermine:oxygen oxidoreductase activity // inferred from electronic annotation /// 0052895 // N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity // inferred from electronic annotation /// 0052901 // spermine:oxygen oxidoreductase (spermidine-forming) activity // inferred from electronic annotation 217075_x_at AF105279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF105279.1 /DEF=Homo sapiens myeloidlymphoid leukemia 2 (MLL2) mRNA, alternatively spliced, partial cds. /FEA=mRNA /GEN=MLL2 /PROD=myeloidlymphoid leukemia 2 /DB_XREF=gi:4588364 /UG=Hs.92236 KIAA0304 gene product AF105279 lysine (K)-specific methyltransferase 2B /// KMT2B /// KMT2B 9757 NM_014727 /// XM_006723513 /// XM_006723514 /// XM_006723515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009994 // oocyte differentiation // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // non-traceable author statement /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217076_s_at Y09980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09980 /DEF=H.sapiens HOXD3 gene /FEA=mRNA_1 /DB_XREF=gi:1869798 /UG=Hs.93574 homeo box D3 Y09980 homeobox D3 /// homeobox D4 /// uncharacterized LOC401021 HOXD3 /// HOXD4 /// LOC401021 3232 /// 3233 /// 401021 NM_006898 /// NM_014621 /// XM_005246509 /// XM_005246510 /// XM_005246511 /// XM_005246512 /// XM_005246513 /// XM_005246514 /// XM_006712477 /// XR_249307 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021615 // glossopharyngeal nerve morphogenesis // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217077_s_at AF095723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF095723.1 /DEF=Homo sapiens GABA-B receptor splice variant 1 mRNA, partial cds. /FEA=mRNA /PROD=GABA-B receptor splice variant 1 /DB_XREF=gi:3719471 /UG=Hs.198612 G protein-coupled receptor 51 AF095723 gamma-aminobutyric acid (GABA) B receptor, 2 GABBR2 9568 NM_005458 /// XM_005252316 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 217078_s_at AJ010102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ010102.1 /DEF=Homo Sapiens mRNA for Natural killer cell IRC1c gene. /FEA=mRNA /GEN=IRC1c /DB_XREF=gi:5706457 /UG=Hs.9688 leukocyte membrane antigen AJ010102 CD300a molecule CD300A 11314 NM_001256841 /// NM_007261 /// XM_005256990 /// XM_005256991 /// XM_005256992 /// XM_006721656 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0033007 // negative regulation of mast cell activation involved in immune response // inferred from direct assay /// 0043305 // negative regulation of mast cell degranulation // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050856 // regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050859 // negative regulation of B cell receptor signaling pathway // inferred from direct assay /// 0051134 // negative regulation of NK T cell activation // inferred from direct assay /// 0060101 // negative regulation of phagocytosis, engulfment // inferred from mutant phenotype /// 1902564 // negative regulation of neutrophil activation // inferred from direct assay /// 1902567 // negative regulation of eosinophil activation // inferred from direct assay /// 1902569 // negative regulation of activation of JAK2 kinase activity // inferred from direct assay /// 2000417 // negative regulation of eosinophil migration // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0038023 // signaling receptor activity // inferred from direct assay 217079_at U82306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82306.1 /DEF=Homo sapiens unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1938333 /UG=Hs.123081 Homo sapiens unknown protein mRNA, partial cds U82306 217080_s_at Y19026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y19026.1 /DEF=Homo sapiens mRNA for Homer-2 protein, Homer-2B splicing form. /FEA=mRNA /GEN=Homer-2 /PROD=Homer-2 protein, Homer-2B splicing form /DB_XREF=gi:6996435 /UG=Hs.93564 Homer, neuronal immediate early gene, 2 Y19026 homer homolog 2 (Drosophila) HOMER2 9455 NM_004839 /// NM_199330 /// NM_199331 /// NM_199332 /// XM_005272448 /// XM_005272449 /// XM_006720775 /// XM_006720776 0007216 // G-protein coupled glutamate receptor signaling pathway // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048875 // chemical homeostasis within a tissue // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0035256 // G-protein coupled glutamate receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217081_at AL031983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031983 /DEF=Human DNA sequence from clone 271M21 on chromosome 6p21.31-22.2. Contains a SMT3B (SMT3H2, Ubiquitin-Like protein) pseudogene, the alternatively spliced GABBR1 gene coding for gamma-aminobutyric acid (GABA) receptor, 1a and 1b, a gene for 7 transm... /FEA=mRNA_1 /DB_XREF=gi:4160199 /UG=Hs.194767 Human DNA sequence from clone 271M21 on chromosome 6p21.31-22.2. Contains a SMT3B (SMT3H2, Ubiquitin-Like protein) pseudogene, the alternatively spliced GABBR1 gene coding for gamma-aminobutyric acid (GABA) receptor, 1a and 1b, a gene for 7 transmembrane AL031983 olfactory receptor, family 2, subfamily H, member 2 OR2H2 7932 NM_007160 /// XM_005249407 /// XM_005272893 /// XM_005274892 /// XM_005275048 /// XM_005275183 /// XM_005275306 /// XM_005275478 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007618 // mating // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 217082_at U82306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U82306.1 /DEF=Homo sapiens unknown protein mRNA, partial cds. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1938333 /UG=Hs.123081 Homo sapiens unknown protein mRNA, partial cds U82306 217083_at AF015124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF015124.1 /DEF=Homo sapiens IgG heavy chain variable region (Vh26) mRNA, partial cds. /FEA=mRNA /GEN=Vh26 /PROD=IgG heavy chain variable region /DB_XREF=gi:2599349 /UG=Hs.123093 Homo sapiens IgG heavy chain variable region (Vh26) mRNA, partial cds AF015124 217084_at AF015124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF015124.1 /DEF=Homo sapiens IgG heavy chain variable region (Vh26) mRNA, partial cds. /FEA=mRNA /GEN=Vh26 /PROD=IgG heavy chain variable region /DB_XREF=gi:2599349 /UG=Hs.123093 Homo sapiens IgG heavy chain variable region (Vh26) mRNA, partial cds AF015124 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 3-23 /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHG1 /// IGHM /// IGHV3-23 /// IGHV4-31 3493 /// 3500 /// 3507 /// 28396 /// 28442 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217085_at AL049328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049328.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564E026 (from clone DKFZp564E026). /FEA=mRNA /DB_XREF=gi:4500102 /UG=Hs.135642 Homo sapiens mRNA; cDNA DKFZp564E026 (from clone DKFZp564E026) AL049328 RP11-116O18.1 217086_at X67513 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X67513.1 /DEF=H.sapiens mRNA for neuronal nAChR beta-3 subunit. /FEA=mRNA /GEN=ACHR /PROD=nicotinic acetylcholine receptor beta-3subunit /DB_XREF=gi:34987 /UG=Hs.96094 cholinergic receptor, nicotinic, beta polypeptide 3 X67513 cholinergic receptor, nicotinic, beta 3 (neuronal) CHRNB3 1142 NM_000749 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0015267 // channel activity // traceable author statement /// 0042166 // acetylcholine binding // inferred from electronic annotation 217087_at AF005081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005081.1 /DEF=Homo sapiens skin-specific protein (xp32) mRNA, partial cds. /FEA=mRNA /GEN=xp32 /PROD=skin-specific protein /DB_XREF=gi:2589189 /UG=Hs.123091 Homo sapiens skin-specific protein (xp32) mRNA, partial cds AF005081 chromosome 1 open reading frame 68 C1orf68 100129271 NM_001024679 0008544 // epidermis development // non-traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 217088_s_at AJ006121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ006121.1 /DEF=Homo sapiens mRNA for NK receptor (NKp46), isoform b. /FEA=mRNA /GEN=NKp46 /PROD=NK receptor, isoform b /DB_XREF=gi:3647268 /UG=Hs.97084 lymphocyte antigen 94 (mouse) homolog (activating NK-receptor ; NK-p46) AJ006121 natural cytotoxicity triggering receptor 1 NCR1 9437 NM_001145457 /// NM_001145458 /// NM_001242356 /// NM_001242357 /// NM_004829 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0042269 // regulation of natural killer cell mediated cytotoxicity // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from sequence or structural similarity 0005057 // receptor signaling protein activity // traceable author statement 217090_at X89655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X89655.1 /DEF=H.sapiens mRNA for cyritestin protein (clone T3). /FEA=mRNA /DB_XREF=gi:3059113 /UG=Hs.98848 a disintegrin and metalloproteinase domain 3a (cyritestin 1) X89655 217091_at X86400 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X86400.1 /DEF=H.sapiens mRNA for gamma subunit of sodium potassium ATPase. /FEA=mRNA /PROD=gamma subunit of sodium potassium ATPase like /DB_XREF=gi:791046 /UG=Hs.19520 FXYD domain-containing ion transport regulator 2 X86400 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005890 // sodium:potassium-exchanging ATPase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // traceable author statement 217092_x_at AL031589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031589 /DEF=Human DNA sequence from clone RP6-11O7 on chromosome 22 Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, part of a putative novel gene, ESTs and GSSs /FEA=CDS /DB_XREF=gi:4914506 /UG=Hs.247871 Human DNA sequence from clone RP6-11O7 on chromosome 22 Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, part of a putative novel gene, ESTs and GSSs AL031589 /// ribosomal protein L7 pseudogene 52 RP6-11O7.2 /// RPL7P52 217093_at S79281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S79281.1 /DEF=pancreatic ribonuclease human, mRNA Recombinant Partial, 491 nt. /FEA=mRNA /GEN=pancreatic ribonuclease, HP-RNase /PROD=pancreatic ribonuclease /DB_XREF=gi:1087118 /UG=Hs.135633 Pancreatic ribonuclease human, mRNA Recombinant Partial, 491 nt S79281 ribonuclease, RNase A family, 1 (pancreatic) RNASE1 6035 NM_002933 /// NM_198232 /// NM_198234 /// NM_198235 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation 217094_s_at AL109923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109923 /DEF=Human DNA sequence from clone RP3-468O1 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands. Contains a gene for the atrophin 1 interacting protein 4 (AIP4), a ferredoxin 1 (FDX1) pseudogene and part of a gene for an ortholog of Rattus norv... /FEA=CDS /DB_XREF=gi:8894632 /UG=Hs.98074 atrophin-1 interacting protein 4 AL109923 itchy E3 ubiquitin protein ligase ITCH 83737 NM_001257137 /// NM_001257138 /// NM_031483 /// XM_005260570 /// XM_006723881 /// XM_006723882 /// XR_244153 /// XR_430315 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002669 // positive regulation of T cell anergy // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0046642 // negative regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046718 // viral entry into host cell // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0090085 // regulation of protein deubiquitination // inferred from sequence or structural similarity 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0045236 // CXCR chemokine receptor binding // inferred from physical interaction 217095_x_at AJ006122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ006122.1 /DEF=Homo sapiens mRNA for NK receptor (NKp46) isoform c. /FEA=mRNA /GEN=NKp46 /PROD=NK receptor,isoform c /DB_XREF=gi:3647270 /UG=Hs.97084 lymphocyte antigen 94 (mouse) homolog (activating NK-receptor ; NK-p46) AJ006122 natural cytotoxicity triggering receptor 1 NCR1 9437 NM_001145457 /// NM_001145458 /// NM_001242356 /// NM_001242357 /// NM_004829 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0042269 // regulation of natural killer cell mediated cytotoxicity // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from sequence or structural similarity 0005057 // receptor signaling protein activity // traceable author statement 217096_at AC004082 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004082 /DEF=Homo sapiens PAC clone RP5-897G10 from 7q11.23-q21.1 /FEA=CDS /DB_XREF=gi:2822160 /UG=Hs.12376 piccolo (presynaptic cytomatrix protein) AC004082 piccolo presynaptic cytomatrix protein PCLO 27445 NM_014510 /// NM_033026 /// XM_006715926 0006810 // transport // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // non-traceable author statement /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005856 // cytoskeleton // non-traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from sequence or structural similarity /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217097_s_at AC004990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004990 /DEF=Homo sapiens PAC clone RP5-1185I7 from 7q11.23-q21 /FEA=CDS_1 /DB_XREF=gi:3924668 /UG=Hs.128653 hypothetical protein DKFZp564F013 AC004990 putative homeodomain transcription factor 2 PHTF2 57157 NM_001127357 /// NM_001127358 /// NM_001127359 /// NM_001127360 /// NM_020432 /// XM_005250508 /// XM_005250509 /// XM_006716063 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 217098_s_at Z98745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98745 /DEF=Human DNA sequence from PAC 29K1 on chromosome 6p21.3-22.2. Contains glutathione peroxidase-like; zinc finger, ESTs, mRNA, STS, tRNAs, olfactory receptor pseudogene /FEA=CDS /DB_XREF=gi:2924249 /UG=Hs.97476 KIAA0426 gene product Z98745 zinc finger and SCAN domain containing 12 ZSCAN12 9753 NM_001039643 /// NM_001163391 /// NM_014724 /// NR_028077 /// XM_006715282 /// XM_006715283 /// XM_006715284 /// XR_427859 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217099_s_at AF258545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF258545 /DEF=Homo sapiens chormosome 17, HC90, HC71AC, HC6 and HC56 genes, complete sequence /FEA=CDS /DB_XREF=gi:10945429 /UG=Hs.19614 gemin4 AF258545 gem (nuclear organelle) associated protein 4 GEMIN4 50628 NM_015721 /// XM_005256667 /// XM_005256668 /// XM_005256670 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217100_s_at AK026451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026451.1 /DEF=Homo sapiens cDNA: FLJ22798 fis, clone KAIA2617. /FEA=mRNA /DB_XREF=gi:10439320 /UG=Hs.127287 KIAA0794 protein AK026451 UBX domain protein 7 UBXN7 26043 NM_015562 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay 217101_at AB007921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007921.1 /DEF=Homo sapiens mRNA for KIAA0452 protein, partial cds. /FEA=mRNA /GEN=KIAA0452 /PROD=KIAA0452 protein /DB_XREF=gi:3413865 /UG=Hs.125783 DEME-6 protein AB007921 tetratricopeptide repeat domain 39A TTC39A 22996 NM_001080494 /// NM_001144832 /// XM_005270641 /// XM_005270643 /// XM_005270644 /// XM_005270645 /// XM_005270646 /// XM_006710471 217102_at AF041410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041410.1 /DEF=Homo sapiens malignancy-associated protein mRNA, partial cds. /FEA=mRNA /PROD=malignancy-associated protein /DB_XREF=gi:2827287 /UG=Hs.99987 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) AF041410 217103_at M28219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M28219.1 /DEF=Homo sapiens low density lipoprotein receptor (FH 10 mutant causing familial hypercholesterolemia) mRNA, 3 end. /FEA=mRNA /GEN=LDLR /PROD=low density lipoprotein receptor /DB_XREF=gi:619785 /UG=Hs.99940 Homo sapiens low density lipoprotein receptor (FH 10 mutant causing familial hypercholesterolemia) mRNA, 3 end M28219 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 217104_at AL109714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109714.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 327506. /FEA=mRNA /DB_XREF=gi:5689826 /UG=Hs.195484 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 327506 AL109714 suppressor of tumorigenicity 20 ST20 400410 NM_001100879 /// NM_001100880 /// NM_001199757 /// NR_037652 /// NR_037653 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005741 // mitochondrial outer membrane // not recorded 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded 217105_at AF041410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041410.1 /DEF=Homo sapiens malignancy-associated protein mRNA, partial cds. /FEA=mRNA /PROD=malignancy-associated protein /DB_XREF=gi:2827287 /UG=Hs.99987 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) AF041410 217106_x_at AF091078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF091078.1 /DEF=Homo sapiens clone 559 unknown mRNA, complete sequence. /FEA=mRNA /PROD=unknown /DB_XREF=gi:3859993 /UG=Hs.125819 putative dimethyladenosine transferase AF091078 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) DIMT1 27292 NM_014473 0000154 // rRNA modification // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016433 // rRNA (adenine) methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0052909 // 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity // inferred from electronic annotation 217107_at AL035603 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035603 /DEF=Human DNA sequence from clone 179E13 on chromosome 6q22.1-22.33. Contains an RPS4 (40S Ribosomal protein S4) pseudogene, ESTS, an STS and GSSs /FEA=CDS /DB_XREF=gi:4775596 /UG=Hs.247869 Human DNA sequence from clone 179E13 on chromosome 6q22.1-22.33. Contains an RPS4 (40S Ribosomal protein S4) pseudogene, ESTS, an STS and GSSs AL035603 ribosomal protein S4X pseudogene 9 /// RPS4XP9 /// RPS4XP9 217108_at X63966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63966.1 /DEF=H.sapiens synthetic gene for platelet-derived growth factor-BB. /FEA=mRNA /PROD=platelet-derived growth factor-BB /DB_XREF=gi:311378 /UG=Hs.135631 H.sapiens synthetic gene for platelet-derived growth factor-BB X63966 0051781 // positive regulation of cell division // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 217109_at AJ242547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ242547.1 /DEF=Homo sapiens partial mRNA for sv7-MUC4 apomucin. /FEA=mRNA /GEN=MUC4 /PROD=sv7-MUC4 apomucin /DB_XREF=gi:7406614 /UG=Hs.198267 mucin 4, tracheobronchial AJ242547 mucin 4, cell surface associated MUC4 4585 NM_004532 /// NM_018406 /// NM_138297 /// NM_138298 /// NM_138299 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005176 // ErbB-2 class receptor binding // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 217110_s_at AJ242547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ242547.1 /DEF=Homo sapiens partial mRNA for sv7-MUC4 apomucin. /FEA=mRNA /GEN=MUC4 /PROD=sv7-MUC4 apomucin /DB_XREF=gi:7406614 /UG=Hs.198267 mucin 4, tracheobronchial AJ242547 mucin 4, cell surface associated MUC4 4585 NM_004532 /// NM_018406 /// NM_138297 /// NM_138298 /// NM_138299 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005176 // ErbB-2 class receptor binding // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 217111_at AK022765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022765.1 /DEF=Homo sapiens cDNA FLJ12703 fis, clone NT2RP1000834, highly similar to Homo sapiens alpha-methylacyl-CoA racemase mRNA. /FEA=mRNA /DB_XREF=gi:10434360 /UG=Hs.128749 alpha-methylacyl-CoA racemase AK022765 alpha-methylacyl-CoA racemase AMACR 23600 NM_001167595 /// NM_001167596 /// NM_001167597 /// NM_001167598 /// NM_014324 /// NM_203382 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from direct assay /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from mutant phenotype /// 0016853 // isomerase activity // inferred from electronic annotation 217112_at Z81010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z81010 /DEF=Human DNA sequence from clone LL22NC03-10C3 on chromosome 22 Contains the PDGFB gene for platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), ESTs, STSs, GSSs and a putative CpG island /FEA=mRNA_1 /DB_XREF=gi:6562180 /UG=Hs.1976 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) Z81010 platelet-derived growth factor beta polypeptide PDGFB 5155 NM_002608 /// NM_033016 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009611 // response to wounding // non-traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038001 // paracrine signaling // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072255 // metanephric glomerular mesangial cell development // inferred from sequence or structural similarity /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072264 // metanephric glomerular endothelium development // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay /// 2000591 // positive regulation of metanephric mesenchymal cell migration // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 217113_at AK022765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022765.1 /DEF=Homo sapiens cDNA FLJ12703 fis, clone NT2RP1000834, highly similar to Homo sapiens alpha-methylacyl-CoA racemase mRNA. /FEA=mRNA /DB_XREF=gi:10434360 /UG=Hs.128749 alpha-methylacyl-CoA racemase AK022765 alpha-methylacyl-CoA racemase AMACR 23600 NM_001167595 /// NM_001167596 /// NM_001167597 /// NM_001167598 /// NM_014324 /// NM_203382 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from direct assay /// 0008111 // alpha-methylacyl-CoA racemase activity // inferred from mutant phenotype /// 0016853 // isomerase activity // inferred from electronic annotation 217114_at Z70200 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z70200 /DEF=H.sapiens gene for U5 snRNP-specific 200kD protein /FEA=CDS /DB_XREF=gi:3255964 /UG=Hs.197800 U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family) Z70200 U5 small nuclear ribonucleoprotein 200 kDa helicase-like /// small nuclear ribonucleoprotein 200kDa (U5) LOC101929240 /// SNRNP200 23020 /// 101929240 NM_014014 /// XR_243770 /// XR_253745 /// XR_424859 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217115_at AL031686 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031686 /DEF=Human DNA sequence from clone 981L23 on chromosome 20q12.1-13.2. Contains a Krueppel type zinc-finger protein pseudogene, a ZNF127 pseudogene and a KRAB box type zinc-finger protein pseudogene. Contains ESTs, an STS ,GSSs and a putative CpG island /FEA=CDS /DB_XREF=gi:4581428 /UG=Hs.247855 Human DNA sequence from clone 981L23 on chromosome 20q12.1-13.2. Contains a Krueppel type zinc-finger protein pseudogene, a ZNF127 pseudogene and a KRAB box type zinc-finger protein pseudogene. Contains ESTs, an STS ,GSSs and a putative CpG island AL031686 makorin ring finger protein 7, pseudogene MKRN7P 7686 NR_026640 217117_x_at AF007194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF007194.1 /DEF=Homo sapiens mucin (MUC3) mRNA, partial cds. /FEA=mRNA /GEN=MUC3 /PROD=mucin /DB_XREF=gi:2853300 /UG=Hs.129782 mucin 3A, intestinal AF007194 mucin 3A, cell surface associated /// mucin 3B, cell surface associated MUC3A /// MUC3B 4584 /// 57876 NM_005960 /// XM_005276299 /// XM_006710192 /// XM_006716217 /// XM_006716218 /// XM_006726442 0007586 // digestion // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // non-traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030197 // extracellular matrix constituent, lubricant activity // non-traceable author statement 217118_s_at AK025608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025608.1 /DEF=Homo sapiens cDNA: FLJ21955 fis, clone HEP05265. /FEA=mRNA /DB_XREF=gi:10438177 /UG=Hs.13255 KIAA0930 protein AK025608 KIAA0930 KIAA0930 23313 NM_001009880 /// NM_015264 217119_s_at Z79783 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z79783 /DEF=H.sapiens G protein-coupled receptor CKR-L2 /FEA=CDS /DB_XREF=gi:2281709 /UG=Hs.198252 G protein-coupled receptor 9 Z79783 chemokine (C-X-C motif) receptor 3 CXCR3 2833 NM_001142797 /// NM_001504 /// XM_005262256 /// XM_005262257 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002685 // regulation of leukocyte migration // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010818 // T cell chemotaxis // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0071954 // chemokine (C-C motif) ligand 11 production // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // traceable author statement /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation /// 0019956 // chemokine binding // inferred from physical interaction /// 0019958 // C-X-C chemokine binding // inferred from direct assay 217120_s_at AK023368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023368.1 /DEF=Homo sapiens cDNA FLJ13306 fis, clone OVARC1001417, highly similar to Homo sapiens thyroid hormone receptor-associated protein complex component TRAP170 mRNA. /FEA=mRNA /DB_XREF=gi:10435273 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) AK023368 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 217121_at AF082559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF082559.1 /DEF=Homo sapiens truncated TRF1-interacting ankyrin-related ADP-ribose polymerase TT9 mRNA, alternatively spliced, partial cds. /FEA=mRNA /PROD=truncated TRF1-interacting ankyrin-relatedADP-ribose polymerase TT9 /DB_XREF=gi:3929224 /UG=Hs.131814 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase AF082559 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase TNKS 8658 NM_003747 /// XM_006716263 0000209 // protein polyubiquitination // inferred from direct assay /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0032210 // regulation of telomere maintenance via telomerase // inferred by curator /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from direct assay /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051225 // spindle assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0070212 // protein poly-ADP-ribosylation // inferred from direct assay /// 0070213 // protein auto-ADP-ribosylation // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000242 // pericentriolar material // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // traceable author statement 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217122_s_at AL031282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031282 /DEF=Human DNA sequence from clone 283E3 on chromosome 1p36.21-36.33. Contains the alternatively spliced gene for Matrix Metalloproteinase in the Female Reproductive tract MIFR1, -2, MMP2122A, -B and -C, a novel gene, the alternatively spliced CDC2L2 ... /FEA=mRNA_6 /DB_XREF=gi:3860395 /UG=Hs.214646 KIAA0447 gene product AL031282 solute carrier family 35, member E2 /// solute carrier family 35, member E2B SLC35E2 /// SLC35E2B 9906 /// 728661 NM_001110781 /// NM_001199787 /// NM_001290264 /// NM_182838 /// XM_006710870 /// XM_006710871 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217123_x_at S64288 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S64288 /DEF=prepro-melanin-concentrating hormone {alternatively spliced, exon IIIv, exon IIv, variant} human, HeLa cell, brain, Genomic, 712 nt /FEA=CDS_1 /DB_XREF=gi:402797 /UG=Hs.247975 Prepro-melanin-concentrating hormone {alternatively spliced, exon IIIv, exon IIv, variant} human, HeLa cell, brain, Genomic, 712 nt S64288 pro-melanin-concentrating hormone-like 1, pseudogene PMCHL1 5369 NM_031887 /// NR_003921 0007268 // synaptic transmission // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement 0030354 // melanin-concentrating hormone activity // inferred from electronic annotation 217124_at AL136792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136792.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P1219 (from clone DKFZp434P1219). /FEA=mRNA /GEN=DKFZp434P1219 /PROD=hypothetical protein /DB_XREF=gi:12053096 /UG=Hs.21361 KIAA1023 protein AL136792 IQ motif containing E IQCE 23288 NM_001100390 /// NM_001287499 /// NM_001287500 /// NM_001287501 /// NM_001287502 /// NM_152558 /// XM_006715676 /// XM_006715677 /// XR_242067 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217125_at X04802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X04802 /DEF=Homo sapiens UBBP2 pseudogene for ubiquitin UBB /FEA=CDS /DB_XREF=gi:37582 /UG=Hs.247890 Homo sapiens UBBP2 pseudogene for ubiquitin UBB X04802 ubiquitin B pseudogene 2 /// UBBP2 /// UBBP2 217126_at K00627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K00627.1 /DEF=human kpni repeat mrna (cdna clone pcd-kpni-8), 3 end. /FEA=mRNA /DB_XREF=gi:337653 /UG=Hs.203776 Human kpni repeat mrna (cdna clone pcd-kpni-8), 3 end K00627 217127_at AL354872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL354872 /DEF=Human DNA sequence from clone RP11-42O15 on chromosome 1. Contains ESTs, STSs, GSSs and a CpG island. Contains the CTH gene for two isoforms of cystathionase (cystathionine gamma-lyase) and a CHORD containing protein 1 (CHP1) pseudogene /FEA=mRNA_1 /DB_XREF=gi:9717070 /UG=Hs.19904 cystathionase (cystathionine gamma-lyase) AL354872 cystathionine gamma-lyase CTH 1491 NM_001190463 /// NM_001902 /// NM_153742 /// XM_005270509 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006534 // cysteine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018272 // protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from electronic annotation /// 0019346 // transsulfuration // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044524 // protein sulfhydration // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0070814 // hydrogen sulfide biosynthetic process // inferred from direct assay /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004123 // cystathionine gamma-lyase activity // inferred from direct assay /// 0004123 // cystathionine gamma-lyase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016846 // carbon-sulfur lyase activity // traceable author statement /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0044540 // L-cystine L-cysteine-lyase (deaminating) // inferred from mutant phenotype /// 0047982 // homocysteine desulfhydrase activity // traceable author statement /// 0080146 // L-cysteine desulfhydrase activity // traceable author statement 217128_s_at AL049688 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049688.1 /DEF=Human gene isolated from PAC 272L16, chromosome 1, similar to calciumcalmodulin dependent protein kinases. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4678721 /UG=Hs.199068 similar to calciumcalmodulin dependent protein kinases AL049688 calcium/calmodulin-dependent protein kinase IG CAMK1G 57172 NM_020439 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217129_at AL031320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031320 /DEF=Human DNA sequence from clone RP1-20N2 on chromosome 6q24. Contains the gene for a novel protein similar to yeast and bacterial cytosine deaminase, a possible pseudogene similar to part of Tubulin beta chain, the PEX3 gene for peroxisomal biogenes... /FEA=CDS_1 /DB_XREF=gi:5457169 /UG=Hs.247889 Human DNA sequence from clone RP1-20N2 on chromosome 6q24. Contains the gene for a novel protein similar to yeast and bacterial cytosine deaminase, a possible pseudogene similar to part of Tubulin beta chain, the PEX3 gene for peroxisomal biogenesis facto AL031320 tubulin beta 8 class VIII pseudogene 2 /// TUBB8P2 /// TUBB8P2 217130_at AF072164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072164.1 /DEF=Homo sapiens HSFE-1 mRNA, partial cds. /FEA=mRNA /GEN=HFSE-1 /PROD=HFSE-1 /DB_XREF=gi:3265149 /UG=Hs.137570 Homo sapiens HSFE-1 mRNA, partial cds AF072164 217131_at AL022151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022151 /DEF=Human DNA sequence from clone 199L16 on chromosome Xq22.1-22.3. Contains a 40S Ribosomal Protein S29 LIKE (pseudo?) gene, an EST, STSs, GSSs and tcta and tatg repeat polymorphisms /FEA=mRNA /DB_XREF=gi:3790137 /UG=Hs.158312 Human DNA sequence from clone 199L16 on chromosome Xq22.1-22.3. Contains a 40S Ribosomal Protein S29 LIKE (pseudo?) gene, an EST, STSs, GSSs and tcta and tatg repeat polymorphisms AL022151 /// ribosomal protein S29 pseudogene 28 RPS29P28 /// RPS29P28 217132_at AF055011 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF055011.1 /DEF=Homo sapiens clone 24587 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3005734 /UG=Hs.137173 Homo sapiens clone 24587 mRNA sequence AF055011 217133_x_at X06399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06399.1 /DEF=Human cytochrome P450 (IIB subfamily) mRNA fragment. /FEA=mRNA /DB_XREF=gi:38271 /UG=Hs.1360 cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 X06399 cytochrome P450, family 2, subfamily B, polypeptide 6 CYP2B6 1555 NM_000767 /// XM_005258569 /// XM_006723050 /// XM_006723051 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042180 // cellular ketone metabolic process // inferred from direct assay /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 217134_at AF216650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF216650.1 /DEF=Homo sapiens putative MTAP (MTAP) mRNA, partial cds, alternatively spliced. /FEA=mRNA /GEN=MTAP /PROD=MTAP /DB_XREF=gi:9082014 /UG=Hs.152817 methylthioadenosine phosphorylase AF216650 methylthioadenosine phosphorylase MTAP 4507 NM_002451 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0017061 // S-methyl-5-thioadenosine phosphorylase activity // traceable author statement 217135_x_at AL031594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031594 /DEF=Human DNA sequence from clone RP4-591N18 on chromosome 22q13.1-13.2 Contains a COX6B (Cytochrome C Oxidase subunit VIb (EC 1.9.3.1)) pseudogene, ESTs, GSSs and two putative CpG islands /FEA=CDS /DB_XREF=gi:5050980 /UG=Hs.247884 Human DNA sequence from clone RP4-591N18 on chromosome 22q13.1-13.2 Contains a COX6B (Cytochrome C Oxidase subunit VIb (EC 1.9.3.1)) pseudogene, ESTs, GSSs and two putative CpG islands AL031594 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) pseudogene 3 /// COX6B1P3 /// COX6B1P3 217136_at AL022240 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022240 /DEF=Human DNA sequence from clone 328E19 on chromosome 1q12-21.2 Contains a cyclophilin-like gene, a novel gene, ESTs, GSSs and STS /FEA=CDS /DB_XREF=gi:4826471 /UG=Hs.247881 Human DNA sequence from clone 328E19 on chromosome 1q12-21.2 Contains a cyclophilin-like gene, a novel gene, ESTs, GSSs and STS AL022240 peptidylprolyl isomerase A (cyclophilin A)-like 4B /// peptidylprolyl isomerase A (cyclophilin A)-like 4C /// peptidylprolyl isomerase A (cyclophilin A)-like 4G PPIAL4B /// PPIAL4C /// PPIAL4G 644591 /// 653505 /// 653598 NM_001123068 /// NM_001135789 /// NM_001143883 /// NM_178230 /// XM_006711714 /// XM_006726367 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 217137_x_at K00627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:K00627.1 /DEF=human kpni repeat mrna (cdna clone pcd-kpni-8), 3 end. /FEA=mRNA /DB_XREF=gi:337653 /UG=Hs.203776 Human kpni repeat mrna (cdna clone pcd-kpni-8), 3 end K00627 217138_x_at AJ249377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ249377.1 /DEF=Homo sapiens partial mRNA for human Ig lambda light chain variable region, clone MB91 (331 bp). /FEA=mRNA /GEN=IGLV /PROD=immunoglobulin lambda variable region /DB_XREF=gi:5911837 /UG=Hs.247898 Human anti-streptococcalanti-myosin immunoglobulin lambda light chain variable region mRNA, partial cds AJ249377 immunoglobulin lambda constant 1 (Mcg marker) IGLC1 3537 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement 217139_at AJ002428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ002428 /DEF=Homo sapiens VDAC1 pseudogene /FEA=CDS /DB_XREF=gi:3183956 /UG=Hs.201553 voltage-dependent anion channel 1 pseudogene AJ002428 voltage-dependent anion channel 1 VDAC1 7416 NM_003374 /// NR_036624 /// NR_036625 /// XM_005272075 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0046930 // pore complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008308 // voltage-gated anion channel activity // inferred from sequence or structural similarity /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 217140_s_at AJ002428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ002428 /DEF=Homo sapiens VDAC1 pseudogene /FEA=CDS /DB_XREF=gi:3183956 /UG=Hs.201553 voltage-dependent anion channel 1 pseudogene AJ002428 voltage-dependent anion channel 1 VDAC1 7416 NM_003374 /// NR_036624 /// NR_036625 /// XM_005272075 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0046930 // pore complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008308 // voltage-gated anion channel activity // inferred from sequence or structural similarity /// 0008308 // voltage-gated anion channel activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 217141_at AL049394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049394.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1819 (from clone DKFZp586B1819). /FEA=mRNA /DB_XREF=gi:4500186 /UG=Hs.13809 hypothetical protein FLJ10648 AL049394 BTB (POZ) domain containing 7 BTBD7 55727 NM_001002860 /// NM_001289133 /// NM_018167 /// XM_006720195 /// XM_006725166 0007275 // multicellular organismal development // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 217142_at AL035687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035687 /DEF=Human DNA sequence from clone RP1-142O9 on chromosome 6p11.1-12.3. Contains an EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) pseudogene, a pseudogene similar to part of ZNF216, ESTs, STSs, GSSs and an aat repeat polymorphism /FEA=CDS /DB_XREF=gi:5295830 /UG=Hs.247893 Human DNA sequence from clone RP1-142O9 on chromosome 6p11.1-12.3. Contains an EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) pseudogene, a pseudogene similar to part of ZNF216, ESTs, STSs, GSSs and an aat repeat polymorphism AL035687 EEF1A1P42 217143_s_at X06557 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X06557.1 /DEF=Human mRNA for TCR-delta chain. /FEA=mRNA /DB_XREF=gi:37003 /UG=Hs.2014 T cell receptor delta locus X06557 SubName: Full=cDNA FLJ52034; /// RecName: Full=T-cell receptor delta chain C region; /// /// YME1-like 1 ATPase TCRDV2 /// TRDC /// TRDC /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217144_at X04801 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X04801 /DEF=Homo sapiens UBBP1 pseudogene for ubiquitin UBB /FEA=CDS /DB_XREF=gi:37581 /UG=Hs.247891 Homo sapiens UBBP1 pseudogene for ubiquitin UBB X04801 ubiquitin B pseudogene 1 /// /// /// ubiquitin B pseudogene 4 UBBP1 /// UBBP1 /// UBBP4 /// UBBP4 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217145_at AF103574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103574.1 /DEF=Homo sapiens isolate donor Z clone Z55K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4323989 /UG=Hs.247907 Homo sapiens isolate donor Z clone Z55K immunoglobulin kappa light chain variable region mRNA, partial cds AF103574 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217146_at AF072468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072468.1 /DEF=Homo sapiens (JH8) mRNA, partial cds. /FEA=mRNA /GEN=JH8 /PROD=unknown /DB_XREF=gi:3435202 /UG=Hs.142296 jerky (mouse) homolog AF072468 Jrk homolog (mouse) JRK 8629 NM_001077527 /// NM_001279352 /// NM_003724 /// XM_006716677 /// XM_006716678 /// XM_006716679 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217147_s_at AJ240085 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ240085.1 /DEF=Homo sapiens mRNA for T-cell receptor interacting molecule protein, splice variant (TRIM gene). /FEA=mRNA /GEN=TRIM /PROD=T-cell receptor interacting molecule, splicevariant /DB_XREF=gi:6911580 /UG=Hs.138701 T-cell receptor interacting molecule AJ240085 T cell receptor associated transmembrane adaptor 1 TRAT1 50852 NM_016388 0001920 // negative regulation of receptor recycling // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from direct assay /// 0051051 // negative regulation of transport // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement 217148_x_at AJ249377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ249377.1 /DEF=Homo sapiens partial mRNA for human Ig lambda light chain variable region, clone MB91 (331 bp). /FEA=mRNA /GEN=IGLV /PROD=immunoglobulin lambda variable region /DB_XREF=gi:5911837 /UG=Hs.247898 Human anti-streptococcalanti-myosin immunoglobulin lambda light chain variable region mRNA, partial cds AJ249377 immunoglobulin lambda constant 1 (Mcg marker) /// immunoglobulin lambda joining 3 /// /// immunoglobulin lambda variable cluster IGLC1 /// IGLJ3 /// IGLV2-14 /// IGLV@ 3537 /// 3546 /// 28831 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217149_x_at AF097738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF097738 /DEF=Homo sapiens non-receptor tyosine kinase (TNK1) gene, complete cds /FEA=mRNA /DB_XREF=gi:4092078 /UG=Hs.203420 tyrosine kinase, non-receptor, 1 AF097738 tyrosine kinase, non-receptor, 1 TNK1 8711 NM_001251902 /// NM_003985 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217150_s_at S73854 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S73854.1 /DEF=NF2=neurofibromatosis type 2 {alternatively spliced, exon 15-16, form E3} human, colorectal cancer, mRNA Partial Mutant, 121 nt. /FEA=mRNA /GEN=NF2 /DB_XREF=gi:688374 /UG=Hs.202718 NF2 S73854 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 217151_at AF103574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103574.1 /DEF=Homo sapiens isolate donor Z clone Z55K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4323989 /UG=Hs.247907 Homo sapiens isolate donor Z clone Z55K immunoglobulin kappa light chain variable region mRNA, partial cds AF103574 uncharacterized LOC101928457 LOC101928457 101928457 XR_245045 /// XR_431452 217152_at AK024136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024136.1 /DEF=Homo sapiens cDNA FLJ14074 fis, clone HEMBB1001869. /FEA=mRNA /DB_XREF=gi:10436442 /UG=Hs.141208 Homo sapiens cDNA FLJ14074 fis, clone HEMBB1001869 AK024136 217153_at U62794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U62794.1 /DEF=Human CDC42 GAP-related protein mRNA, partial cds. /FEA=mRNA /PROD=CDC42 GAP-related protein /DB_XREF=gi:2326170 /UG=Hs.138860 Rho GTPase activating protein 1 U62794 Rho GTPase activating protein 1 ARHGAP1 392 NM_004308 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 217154_s_at AL035250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035250 /DEF=Human DNA sequence from clone RP4-614C15 on chromosome 20q13.2-13.33 Contains the EDN3 gene for endothelin 3. ESTs, STSs, GSS and a putative CpG island /FEA=mRNA_4 /DB_XREF=gi:10198624 /UG=Hs.1408 endothelin 3 AL035250 endothelin 3 EDN3 1908 NM_000114 /// NM_207032 /// NM_207033 /// NM_207034 /// XM_005260312 /// XM_005260313 /// XM_005260314 /// XM_006723734 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from direct assay /// 0014826 // vein smooth muscle contraction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0042310 // vasoconstriction // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from direct assay 217155_at AL049714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049714 /DEF=Human DNA sequence from clone 181J22 on chromosome 11p13. Contains an RPL34 (60S Ribosomal protein L34) pseudogene, ESTs and GSSs /FEA=CDS /DB_XREF=gi:5679560 /UG=Hs.247903 ribosomal protein L34 pseudogene 2 AL049714 RP1-181J22.1 217156_at U04628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U04628 /DEF=Human 78 kDa gastrin binding protein GBP gene, complete cds /FEA=CDS /DB_XREF=gi:606608 /UG=Hs.247943 Human 78 kDa gastrin binding protein GBP gene, complete cds U04628 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1 /// HADHAP1 /// HADHAP1 217157_x_at AF103530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF103530.1 /DEF=Homo sapiens isolate donor N clone N8K immunoglobulin kappa light chain variable region mRNA, partial cds. /FEA=mRNA /PROD=immunoglobulin kappa light chain variableregion /DB_XREF=gi:4378389 /UG=Hs.247911 Homo sapiens isolate donor N clone N8K immunoglobulin kappa light chain variable region mRNA, partial cds AF103530 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217158_at X97875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X97875 /DEF=H.sapiens EP4 prostaglandin receptor pseudogene c16g7 /FEA=CDS /DB_XREF=gi:1359737 /UG=Hs.247972 H.sapiens EP4 prostaglandin receptor pseudogene c16g7 X97875 PTGER4P2-CDK2AP2P2 readthrough transcribed pseudogene PTGER4P2-CDK2AP2P2 442421 NR_024496 217159_x_at AJ130712 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ130712.1 /DEF=Homo sapiens mRNA for QA79 membrane protein, splice product airm-3. /FEA=mRNA /GEN=airm /PROD=QA79 membrane protein, splice product airm-3 /DB_XREF=gi:5541873 /UG=Hs.149250 D-siglec precursor, AJ130712 sialic acid binding Ig-like lectin 7 SIGLEC7 27036 NM_001277201 /// NM_014385 /// NM_016543 /// NR_102350 /// XM_006723140 0007155 // cell adhesion // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // traceable author statement 217160_at M94893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M94893.1 /DEF=Human testis-specific protein (TSPY) mRNA, 3 end, clone pJA923. /FEA=mRNA /GEN=TSPY /PROD=testis-specific protein /DB_XREF=gi:340008 /UG=Hs.2051 testis specific protein, Y-linked M94893 testis specific protein, Y-linked 1 TSPY1 7258 NM_001197242 /// NM_003308 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007506 // gonadal mesoderm development // inferred from electronic annotation /// 0007548 // sex differentiation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217161_x_at X17406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X17406.1 /DEF=Human mRNA for cartilage specific proteoglycan. /FEA=mRNA /PROD=cartilage specific proteoglycan (600 AA) /DB_XREF=gi:30248 /UG=Hs.2159 aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) X17406 aggrecan ACAN 176 NM_001135 /// NM_013227 /// XM_006720419 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030166 // proteoglycan biosynthetic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217162_at M94893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M94893.1 /DEF=Human testis-specific protein (TSPY) mRNA, 3 end, clone pJA923. /FEA=mRNA /GEN=TSPY /PROD=testis-specific protein /DB_XREF=gi:340008 /UG=Hs.2051 testis specific protein, Y-linked M94893 217163_at X63118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63118 /DEF=H.sapiens DNA for oestrogen receptor gene promoter /FEA=CDS /DB_XREF=gi:35159 /UG=Hs.247938 H.sapiens DNA for oestrogen receptor gene promoter X63118 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217164_at AK024108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024108.1 /DEF=Homo sapiens cDNA FLJ14046 fis, clone HEMBA1006461. /FEA=mRNA /DB_XREF=gi:10436406 /UG=Hs.142677 Homo sapiens cDNA FLJ14046 fis, clone HEMBA1006461 AK024108 217165_x_at M10943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M10943 /DEF=Human metallothionein-If gene (hMT-If) /FEA=CDS /DB_XREF=gi:187540 /UG=Hs.203936 metallothionein 1F (functional) M10943 metallothionein 1F MT1F 4494 NM_005949 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217166_at J04798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J04798 /DEF=Human prothymosin-alpha pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:190368 /UG=Hs.247931 Human prothymosin-alpha pseudogene, complete sequence J04798 /// prothymosin, alpha pseudogene 1 (gene sequence 26) PTMAP1 /// PTMAP1 217167_x_at AJ252550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ252550 /DEF=Homo sapiens partial GK gene for glycerol kinase, exon 1 (glycerol kinase deficiency case) /FEA=CDS_1 /DB_XREF=gi:5834425 /UG=Hs.1466 glycerol kinase AJ252550 glycerol kinase GK 2710 NM_000167 /// NM_001128127 /// NM_001205019 /// NM_203391 /// XM_005274488 /// XM_006724483 /// XM_006724484 /// XM_006724485 /// XM_006724486 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006071 // glycerol metabolic process // inferred from mutant phenotype /// 0006072 // glycerol-3-phosphate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019563 // glycerol catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046167 // glycerol-3-phosphate biosynthetic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004370 // glycerol kinase activity // inferred from mutant phenotype /// 0004370 // glycerol kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 217168_s_at AF217990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF217990.1 /DEF=Homo sapiens clone PP1722 unknown mRNA. /FEA=mRNA /PROD=unknown /DB_XREF=gi:10441910 /UG=Hs.146393 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 AF217990 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 HERPUD1 9709 NM_001010989 /// NM_001010990 /// NM_001272103 /// NM_014685 /// XM_006721352 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from expression pattern /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217169_at M31949 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M31949 /DEF=Human Ig rearranged mu-chain V-region gene, subgroup VH-III, exon 1 and 2 /FEA=CDS /DB_XREF=gi:185254 /UG=Hs.247923 Human Ig rearranged mu-chain V-region gene, subgroup VH-III, exon 1 and 2 M31949 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant mu IGHA1 /// IGHG1 /// IGHM 3493 /// 3500 /// 3507 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217170_at AE000659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AE000659 /DEF=Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence /FEA=CDS_14 /DB_XREF=gi:2358025 /UG=Hs.247915 T cell receptor alpha variable 8-6 AE000659 Homo sapiens mRNA for unknown variable region, clone: SEB 74. /// T cell receptor alpha variable 8-6 /// TCRA /// TRAV8-6 /// TRAV8-6 0005515 // protein binding // inferred from electronic annotation 217171_at M81780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M81780 /DEF=Homo sapiens acid sphingomyelinase (SMPD1) gene, complete cds, ORFs 1-3, complete cdss /FEA=CDS_2 /DB_XREF=gi:972768 /UG=Hs.247962 Homo sapiens acid sphingomyelinase (SMPD1) gene, complete cds, ORFs 1-3, complete cdss M81780 sphingomyelin phosphodiesterase 1, acid lysosomal SMPD1 6609 NM_000543 /// NM_001007593 /// NR_027400 /// XM_005253075 0006665 // sphingolipid metabolic process // traceable author statement /// 0006684 // sphingomyelin metabolic process // traceable author statement /// 0006685 // sphingomyelin catabolic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0042599 // lamellar body // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 217172_at X84340 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X84340.1 /DEF=H.sapiens mRNA for Ig light chain, variable region (ID:CLL001VL). /FEA=mRNA /GEN=Ig VL gene /PROD=immunoglobulin light chain variable region /DB_XREF=gi:791011 /UG=Hs.247950 H.sapiens mRNA for Ig light chain, variable region (ID:CLL001VL) X84340 217173_s_at S70123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S70123.1 /DEF=Homo sapiens low density lipoprotein receptor mRNA, partial cds. /FEA=mRNA /PROD=low density lipoprotein receptor /DB_XREF=gi:546107 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) S70123 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 217174_s_at AL078616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL078616.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 179130. /FEA=mRNA /DB_XREF=gi:5042255 /UG=Hs.20912 adenomatous polyposis coli like AL078616 adenomatosis polyposis coli 2 APC2 10297 NM_005883 /// XM_005259475 /// XM_006722607 /// XM_006722608 /// XM_006722609 /// XM_006722610 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0035414 // negative regulation of catenin import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from electronic annotation 217175_at U06641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U06641.1 /DEF=Human UDP glucuronosyltransferase mRNA, partial cds. /FEA=mRNA /PROD=UDP glucuronosyltransferase /DB_XREF=gi:458398 /UG=Hs.150207 UDP glycosyltransferase 2 family, polypeptide B15 U06641 217176_s_at X59740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X59740.1 /DEF=Human ZFX mRNA for put. transcription activator, isoform 3. /FEA=mRNA /GEN=ZFX /PROD=ZFX product, isoform 3 /DB_XREF=gi:38023 /UG=Hs.2074 zinc finger protein, X-linked X59740 zinc finger protein, X-linked ZFX 7543 NM_001178084 /// NM_001178085 /// NM_001178086 /// NM_001178095 /// NM_003410 /// XM_005274591 /// XM_005274592 /// XM_005274594 /// XM_006724513 /// XM_006724514 /// XM_006724515 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060746 // parental behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217177_s_at AL080103 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080103.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564N2216 (from clone DKFZp564N2216). /FEA=mRNA /DB_XREF=gi:5262528 /UG=Hs.149770 Homo sapiens cDNA FLJ13658 fis, clone PLACE1011567 AL080103 protein tyrosine phosphatase, receptor type, B PTPRB 5787 NM_001109754 /// NM_001206971 /// NM_001206972 /// NM_002837 /// XM_006719528 /// XM_006719529 /// XM_006719530 /// XR_245948 /// XR_245949 0001525 // angiogenesis // inferred from electronic annotation /// 0006470 // protein dephosphorylation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 217178_at L12060 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L12060.1 /DEF=Homo sapiens retinoic acid receptor (gamma-7) mRNA. /FEA=mRNA /DB_XREF=gi:307424 /UG=Hs.1497 retinoic acid receptor, gamma L12060 retinoic acid receptor, gamma RARG 5916 NM_000966 /// NM_001042728 /// NM_001243730 /// NM_001243731 /// NM_001243732 /// XM_005269054 /// XM_005269055 /// XM_005269056 /// XM_005269057 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0003430 // growth plate cartilage chondrocyte growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // traceable author statement /// 0060173 // limb development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060429 // epithelium development // inferred from electronic annotation /// 0060534 // trachea cartilage development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070384 // Harderian gland development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity 217179_x_at X79782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79782.1 /DEF=H.sapiens (T1.1) mRNA for IG lambda light chain. /FEA=mRNA /PROD=immunoglobulin lambda light chain /DB_XREF=gi:506428 /UG=Hs.247949 H.sapiens (T1.1) mRNA for IG lambda light chain X79782 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003823 // antigen binding // inferred from electronic annotation /// 0003823 // antigen binding // non-traceable author statement 217180_at X79782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X79782.1 /DEF=H.sapiens (T1.1) mRNA for IG lambda light chain. /FEA=mRNA /PROD=immunoglobulin lambda light chain /DB_XREF=gi:506428 /UG=Hs.247949 H.sapiens (T1.1) mRNA for IG lambda light chain X79782 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0003823 // antigen binding // inferred from electronic annotation /// 0003823 // antigen binding // non-traceable author statement 217181_at M22005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M22005 /DEF=Human interleukin 2 gene, clone pATtacIL-2C2TT, complete cds, clone pATtacIL-2C2TT /FEA=CDS /DB_XREF=gi:186300 /UG=Hs.247956 Human interleukin 2 gene, clone pATtacIL-2C2TT, complete cds, clone pATtacIL-2C2TT M22005 217182_at Z34282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z34282.1 /DEF=H.sapiens (MAR11) MUC5AC mRNA for mucin (partial). /FEA=mRNA /GEN=MUC5AC /PROD=mucin /DB_XREF=gi:563384 /UG=Hs.247953 H.sapiens (MAR11) MUC5AC mRNA for mucin (partial) Z34282 217183_at S70123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S70123.1 /DEF=Homo sapiens low density lipoprotein receptor mRNA, partial cds. /FEA=mRNA /PROD=low density lipoprotein receptor /DB_XREF=gi:546107 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) S70123 SPC24, NDC80 kinetochore complex component SPC24 147841 NM_182513 /// XM_005259753 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031262 // Ndc80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217184_s_at X52213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52213.1 /DEF=H.sapiens ltk mRNA. /FEA=mRNA /GEN=ltk /DB_XREF=gi:34421 /UG=Hs.210 leukocyte tyrosine kinase X52213 leukocyte receptor tyrosine kinase LTK 4058 NM_001135685 /// NM_002344 /// NM_206961 /// XM_005254381 /// XM_005254382 /// XM_006720505 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217185_s_at Z95118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z95118 /DEF=Human DNA sequence from clone 354J5 on chromosome 6q21-22. Contains pseudogene similar to zinc finger protein (ZPR1), EST, STS, GSS /FEA=CDS /DB_XREF=gi:3821018 /UG=Hs.211509 zinc finger protein 259, pseudogene Z95118 zinc finger protein 259 pseudogene 1 /// ZPR1 zinc finger ZNF259P1 /// ZPR1 8882 /// 442240 NM_003904 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001834 // trophectodermal cell proliferation // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030576 // Cajal body organization // inferred from mutant phenotype /// 0030576 // Cajal body organization // inferred from sequence or structural similarity /// 0031641 // regulation of myelination // inferred from sequence or structural similarity /// 0033120 // positive regulation of RNA splicing // inferred from mutant phenotype /// 0042023 // DNA endoreduplication // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0061564 // axon development // inferred from mutant phenotype /// 0061564 // axon development // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 1902742 // apoptotic process involved in development // inferred from sequence or structural similarity /// 1990261 // pre-mRNA catabolic process // inferred from mutant phenotype /// 2000672 // negative regulation of motor neuron apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032797 // SMN complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031369 // translation initiation factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217186_at Z95118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z95118 /DEF=Human DNA sequence from clone 354J5 on chromosome 6q21-22. Contains pseudogene similar to zinc finger protein (ZPR1), EST, STS, GSS /FEA=CDS /DB_XREF=gi:3821018 /UG=Hs.211509 zinc finger protein 259, pseudogene Z95118 zinc finger protein 259 pseudogene 1 ZNF259P1 442240 217187_at Z34282 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z34282.1 /DEF=H.sapiens (MAR11) MUC5AC mRNA for mucin (partial). /FEA=mRNA /GEN=MUC5AC /PROD=mucin /DB_XREF=gi:563384 /UG=Hs.247953 H.sapiens (MAR11) MUC5AC mRNA for mucin (partial) Z34282 mucin 5AC, oligomeric mucus/gel-forming MUC5AC 4586 NM_017511 /// XM_006709945 /// XM_006709947 /// XM_006718399 /// XM_006726526 /// XM_006726528 0016266 // O-glycan processing // traceable author statement /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043205 // fibril // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement 217188_s_at AC007182 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007182 /DEF=untitled /FEA=CDS_3 /DB_XREF=gi:5708446 /UG=Hs.15106 chromosome 14 open reading frame 1 AC007182 chromosome 14 open reading frame 1 C14orf1 11161 NM_007176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030133 // transport vesicle // inferred from direct assay 217189_s_at AL137800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137800 /DEF=Human DNA sequence from clone RP1-127C7 on chromosome 1q25.1-31.1 Contains the gene for KIAA0250 protein, the NCF2 (neutrophil cytosolic factor 2 (65kD,chronic granulomatous disease, autosomal 2) gene, the 3 end of the gene for ARPC5 (actin relat... /FEA=CDS_2 /DB_XREF=gi:9926422 /UG=Hs.15087 KIAA0250 gene product AL137800 SMG7 nonsense mediated mRNA decay factor SMG7 9887 NM_001174061 /// NM_014837 /// NM_173156 /// NM_201568 /// NM_201569 /// XM_005245647 /// XM_005245648 /// XM_005245649 /// XM_005245652 /// XM_005245653 /// XM_005245654 /// XM_005245655 /// XM_005245656 /// XM_006711674 /// XM_006711675 /// XM_006711676 /// XM_006711677 /// XM_006711678 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 217190_x_at S67777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S67777 /DEF=estrogen receptor {exon 6} human, tamoxifen-resistant breast tumor 17, Genomic Mutant, 187 nt /FEA=CDS_1 /DB_XREF=gi:459362 /UG=Hs.247976 Estrogen receptor {exon 6} human, tamoxifen-resistant breast tumor 17, Genomic Mutant, 187 nt S67777 estrogen receptor 1 ESR1 2099 NM_000125 /// NM_001122740 /// NM_001122741 /// NM_001122742 /// NM_001291230 /// NM_001291241 /// XM_006715374 /// XM_006715375 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from sequence or structural similarity /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from sequence or structural similarity /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060065 // uterus development // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0060523 // prostate epithelial cord elongation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // non-traceable author statement /// 0030284 // estrogen receptor activity // non-traceable author statement /// 0034056 // estrogen response element binding // inferred from direct assay /// 0038052 // estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from genetic interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217191_x_at AF042163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF042163 /DEF=Homo sapiens cytochrome c oxidase subunit VIc (COX6CP1) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3861484 /UG=Hs.248205 cytochrome c oxidase subunit VIc pseudogene 1 AF042163 cytochrome c oxidase subunit VIc pseudogene 1 /// COX6CP1 /// COX6CP1 217192_s_at AL022067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022067 /DEF=Human DNA sequence from clone 134E15 on chromosome 6q21 Contains Blimp-1, apoptosis specific protein similar to yeast APG5 ESTs, GSSs and retroviral sequence /FEA=CDS_1 /DB_XREF=gi:3395491 /UG=Hs.158303 PR domain containing 1, with ZNF domain AL022067 PR domain containing 1, with ZNF domain PRDM1 639 NM_001198 /// NM_182907 /// XM_005267094 /// XM_006715550 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217193_x_at X93006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X93006.1 /DEF=H.sapiens mRNA for IgG lambda light chain V-J-C region (clone Tgl11). /FEA=mRNA /PROD=immunoglobulin lambda light chain VJC region /DB_XREF=gi:1070333 /UG=Hs.248030 H.sapiens mRNA for IgG lambda light chain V-J-C region (clone Tgl11) X93006 217194_at AB007970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007970.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0501. /FEA=mRNA /DB_XREF=gi:3413945 /UG=Hs.223020 Homo sapiens mRNA, chromosome 1 specific transcript KIAA0501 AB007970 217195_at L42230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L42230 /DEF=Homo sapiens core 2 beta-1,6-N-acetylglucosaminyltransferase pseudogene /FEA=CDS /DB_XREF=gi:1019163 /UG=Hs.247990 Homo sapiens core 2 beta-1,6-N-acetylglucosaminyltransferase pseudogene L42230 glucosaminyl (N-acetyl) transferase 1, core 2 pseudogene 1 /// GCNT1P1 /// GCNT1P1 217196_s_at AL110158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110158.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F0424 (from clone DKFZp586F0424); partial cds. /FEA=mRNA /GEN=DKFZp586F0424 /PROD=hypothetical protein /DB_XREF=gi:5817061 /UG=Hs.23585 KIAA1078 protein AL110158 calmodulin regulated spectrin-associated protein family, member 2 CAMSAP2 23271 NM_203459 /// XM_005245040 /// XM_005245041 /// XM_005245042 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0033043 // regulation of organelle organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0051011 // microtubule minus-end binding // inferred from direct assay 217197_x_at AL049785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049785.1 /DEF=Novel human gene mapping to chomosome 13. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4902706 /UG=Hs.22174 Novel human gene mapping to chomosome 13 AL049785 NEDD4 binding protein 2-like 1 N4BP2L1 90634 NM_001079691 /// NM_001286459 /// NM_001286460 /// NM_001286461 /// NM_052818 /// XM_006719890 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 217198_x_at U80164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80164 /DEF=Human immunoglobulin heavy chain variable region (V4-30.2) gene, partial cds /FEA=CDS /DB_XREF=gi:1791170 /UG=Hs.247989 Human immunoglobulin heavy chain variable region (V4-30.2) gene, partial cds U80164 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) IGH /// IGHA2 /// IGHD /// IGHG1 3492 /// 3494 /// 3495 /// 3500 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // non-traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217199_s_at S81491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S81491 /DEF=Stat2 type a=signal transducer and activator of transcription...Stat2 type a short isoform {alternatively spliced, exons 20-21} human, hepatoblastoma cell line Hep3B, Genomic, 3 genes, 354 nt /FEA=CDS_1 /DB_XREF=gi:1478435 /UG=Hs.247981 Stat2 type a S81491 signal transducer and activator of transcription 2, 113kDa STAT2 6773 NM_005419 /// NM_198332 /// XM_005269108 /// XM_005269109 /// XM_005269110 /// XM_005269111 /// XM_006719572 /// XR_245953 /// XR_245954 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 217200_x_at U06715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U06715.1 /DEF=Human cytochrome B561, HCYTO B561, mRNA, partial cds. /FEA=mRNA /GEN=B561 /PROD=HCYTO B561 /DB_XREF=gi:476590 /UG=Hs.153028 cytochrome b-561 U06715 cytochrome b561 CYB561 1534 NM_001017916 /// NM_001017917 /// NM_001017918 /// NM_001915 /// XM_005257090 /// XM_005257091 /// XM_005257092 /// XM_006721727 0022900 // electron transport chain // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000293 // ferric-chelate reductase activity // inferred from sequence or structural similarity /// 0022865 // transmembrane electron transfer carrier // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217201_at AB007970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007970.1 /DEF=Homo sapiens mRNA, chromosome 1 specific transcript KIAA0501. /FEA=mRNA /DB_XREF=gi:3413945 /UG=Hs.223020 Homo sapiens mRNA, chromosome 1 specific transcript KIAA0501 AB007970 RAS protein activator like 2 RASAL2 9462 NM_004841 /// NM_170692 /// XM_005245620 /// XM_005245621 /// XM_005245622 /// XM_006711634 0007165 // signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 217202_s_at U08626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U08626 /DEF=Human glutamine synthetase pseudogene /FEA=CDS /DB_XREF=gi:551473 /UG=Hs.247984 Human glutamine synthetase pseudogene U08626 glutamate-ammonia ligase GLUL 2752 NM_001033044 /// NM_001033056 /// NM_002065 /// XM_006711278 0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006542 // glutamine biosynthetic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045503 // dynein light chain binding // inferred from electronic annotation 217203_at U08626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U08626 /DEF=Human glutamine synthetase pseudogene /FEA=CDS /DB_XREF=gi:551473 /UG=Hs.247984 Human glutamine synthetase pseudogene U08626 glutamate-ammonia ligase (glutamine synthetase) pseudogene 4 /// GLULP4 /// GLULP4 217204_at AL049992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049992.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564G242 (from clone DKFZp564G242). /FEA=mRNA /DB_XREF=gi:4884244 /UG=Hs.225836 Homo sapiens mRNA; cDNA DKFZp564G242 (from clone DKFZp564G242) AL049992 mitochondrial translational release factor 1-like MTRF1L 54516 NM_001114184 /// NM_019041 /// XM_005267035 /// XM_005267036 /// XM_005267037 /// XR_245540 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0003747 // translation release factor activity // inferred from electronic annotation /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation 217205_at Y08772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y08772 /DEF=H.sapiens PABII pseudogene /FEA=CDS /DB_XREF=gi:1770485 /UG=Hs.247983 H.sapiens PABII pseudogene Y08772 AL590762.11 217206_at D00267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D00267 /DEF=Homo sapiens pseudogene for cytochrome c-like protein, clone pHGC4E1 /FEA=CDS /DB_XREF=gi:219559 /UG=Hs.248014 Homo sapiens pseudogene for cytochrome c-like protein, clone pHGC4E1 D00267 cytochrome c, somatic pseudogene 19 /// CYCSP19 /// RP11-3L10.1 217207_s_at AK025267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025267.1 /DEF=Homo sapiens cDNA: FLJ21614 fis, clone COL07391, highly similar to AB020625 Homo sapiens mRNA for butyrophilin like receptor. /FEA=mRNA /DB_XREF=gi:10437746 /UG=Hs.225949 butyrophilin-like 3 AK025267 butyrophilin-like 3 BTNL3 10917 NM_006707 /// NM_197975 /// XM_005265801 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217208_s_at AL121981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121981 /DEF=Human DNA sequence from clone RP5-1061C18 on chromosome 1p36.22-36.33. Contains ESTs, STSs, GSSs and a CpG island. Contains the 5 part of the DLG1 gene encoding the discs protein (large Drosophila homolog 1, presynaptic protein SAP97) with five i... /FEA=CDS_2 /DB_XREF=gi:9931107 /UG=Hs.154294 discs, large (Drosophila) homolog 1 AL121981 discs, large homolog 1 (Drosophila) DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 217209_at X16454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16454 /DEF=Human gene for carcinoembryonic antigen subdomains A and B /FEA=CDS /DB_XREF=gi:29852 /UG=Hs.248025 Human gene for carcinoembryonic antigen subdomains A and B X16454 carcinoembryonic antigen-related cell adhesion molecule 3 CEACAM3 1084 NM_001277163 /// NM_001815 /// NR_102333 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217210_at AL031737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031737 /DEF=Human DNA sequence from clone 8B22 on chromosome 1p35.1-36.21 Contains gene similar to cytoplasmic dynein light chain 1, GSSs /FEA=CDS /DB_XREF=gi:4464258 /UG=Hs.225980 Human DNA sequence from clone 8B22 on chromosome 1p35.1-36.21 Contains gene similar to cytoplasmic dynein light chain 1, GSSs AL031737 RP1-8B22.1 217211_at D50604 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D50604 /DEF=Human beta-cytoplasmic actin (ACTBP9) pseudogene /FEA=CDS /DB_XREF=gi:2094759 /UG=Hs.248007 Human beta-cytoplasmic actin (ACTBP9) pseudogene D50604 /// actin, beta pseudogene 9 ACTBP9 /// ACTBP9 217212_s_at Z84723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z84723 /DEF=Human DNA sequence from phage LAW2 from a contig from the tip of the short arm of chromosome 16, spanning 2Mb of 16p13.3 Contains Interleukin 9 receptor pseudogene /FEA=CDS /DB_XREF=gi:1817581 /UG=Hs.247991 Human DNA sequence from phage LAW2 from a contig from the tip of the short arm of chromosome 16, spanning 2Mb of 16p13.3 Contains Interleukin 9 receptor pseudogene Z84723 interleukin 9 receptor IL9R 3581 NM_002186 /// NM_176786 /// XM_006724817 /// XM_006724880 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0038113 // interleukin-9-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004919 // interleukin-9 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019983 // interleukin-9 binding // inferred from electronic annotation 217213_at AB022847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB022847.1 /DEF=Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds. /FEA=mRNA /PROD=norepinephrine transporter isoform 2 /DB_XREF=gi:5360690 /UG=Hs.225971 Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds AB022847 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 217214_s_at AB022847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB022847.1 /DEF=Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds. /FEA=mRNA /PROD=norepinephrine transporter isoform 2 /DB_XREF=gi:5360690 /UG=Hs.225971 Homo sapiens mRNA for norepinephrine transporter isoform 2, partial cds AB022847 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 217215_s_at Z82180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z82180 /DEF=Human DNA sequence from clone LL22NC01-81G9 on chromosome 22 Contains part of novel gene EAN57 and GSSs /FEA=mRNA /DB_XREF=gi:5051358 /UG=Hs.225954 hypothetical protein Z82180 217216_x_at AC006530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006530 /DEF=untitled /FEA=CDS_5 /DB_XREF=gi:4680764 /UG=Hs.153820 hypothetical protein AC006530 mutL homolog 3 MLH3 27030 NM_001040108 /// NM_014381 /// XM_005267531 /// XM_005267532 /// XM_005267533 /// XM_005267534 /// XM_006720116 /// XM_006720117 /// XR_245681 /// XR_429311 /// XR_429312 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // non-traceable author statement /// 0007140 // male meiosis // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005712 // chiasma // not recorded /// 0032300 // mismatch repair complex // not recorded /// 0032390 // MutLbeta complex // 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0019237 // centromeric DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // 217217_at X95660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95660.1 /DEF=H.sapiens mRNA for variable region of IgA (VH4 family). /FEA=mRNA /PROD=variable region of IgA /DB_XREF=gi:1261909 /UG=Hs.248023 H.sapiens mRNA for variable region of IgA (VH4 family) X95660 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 /// putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like IGHA1 /// IGHA2 /// IGHG1 /// IGHG4 /// IGHM /// IGHV4-31 /// LOC102723407 3493 /// 3494 /// 3500 /// 3503 /// 3507 /// 28396 /// 102723407 XM_006724899 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217218_at AK027005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027005.1 /DEF=Homo sapiens cDNA: FLJ23352 fis, clone HEP14219. /FEA=mRNA /DB_XREF=gi:10440009 /UG=Hs.154978 KIAA0261 protein AK027005 wings apart-like homolog (Drosophila) WAPAL 23063 NM_015045 /// XM_006717726 /// XM_006717727 /// XM_006717728 /// XM_006717729 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from mutant phenotype /// 0045875 // negative regulation of sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype 0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217219_at AL080191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080191.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A062 (from clone DKFZp434A062); partial cds. /FEA=mRNA /GEN=DKFZp434A062 /PROD=hypothetical protein /DB_XREF=gi:5262671 /UG=Hs.226001 DKFZP434A062 protein AL080191 uncharacterized LOC26102 DKFZP434A062 26102 NR_026964 217220_at AL050153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050153.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586K1520 (from clone DKFZp586K1520). /FEA=mRNA /GEN=DKFZp586K1520 /PROD=hypothetical protein /DB_XREF=gi:4884364 /UG=Hs.225987 DKFZP586K1520 protein AL050153 uncharacterized LOC100287387 LOC100287387 100287387 XM_002342310 /// XM_003403761 /// XM_003960314 217221_x_at AL137421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137421.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434P072 (from clone DKFZp434P072); partial cds. /FEA=mRNA /GEN=DKFZp434P072 /PROD=hypothetical protein /DB_XREF=gi:6807975 /UG=Hs.154583 RNA binding motif protein 10 AL137421 RNA binding motif protein 10 RBM10 8241 NM_001204466 /// NM_001204467 /// NM_001204468 /// NM_005676 /// NM_152856 /// XM_005272677 /// XM_005272678 /// XM_005272679 /// XM_006724563 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0034391 // regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217222_at S74639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S74639.1 /DEF=Ig VH4=Ig heavy chain variable region {clone C20} human, systemic lupus erythematosus, mRNA Partial, 405 nt. /FEA=mRNA /GEN=Ig VH4 /PROD=Ig heavy chain variable region /DB_XREF=gi:807023 /UG=Hs.248035 Ig VH4 S74639 immunoglobulin heavy constant gamma 1 (G1m marker) IGHG1 3500 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217223_s_at U07000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U07000 /DEF=Human breakpoint cluster region (BCR) gene, complete cds /FEA=CDS_4 /DB_XREF=gi:487344 /UG=Hs.234799 breakpoint cluster region U07000 breakpoint cluster region BCR 613 NM_004327 /// NM_021574 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043314 // negative regulation of neutrophil degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 217224_at U53583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U53583 /DEF=Human chromosome 17 cosmid ICRF105cF06137 olfactory receptor gene cluster: olfactory receptor 17-4 (OLFR 17-4) gene, partial cds, olfactory receptor 17-210 (OLFR 17-210) gene, complete cds, olfactory receptor 17-209 (OLFR 17-209) gene, complete cds /FEA=CDS_1 /DB_XREF=gi:4090430 /UG=Hs.248182 olfactory receptor, family 1, subfamily E, member 3 pseudogene U53583 olfactory receptor, family 1, subfamily E, member 3 (gene/pseudogene) /// OR1E3 /// OR1E3 217225_x_at AL512687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL512687.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547A1913 (from clone DKFZp547A1913). /FEA=mRNA /GEN=DKFZp547A1913 /PROD=hypothetical protein /DB_XREF=gi:12224839 /UG=Hs.227823 pM5 protein AL512687 uncharacterized LOC101060373 /// NODAL modulator 1 /// NODAL modulator 2 /// NODAL modulator 3 LOC101060373 /// NOMO1 /// NOMO2 /// NOMO3 23420 /// 283820 /// 408050 /// 101060373 NM_001004060 /// NM_001004067 /// NM_014287 /// NM_173614 /// XM_005255318 /// XM_006725195 /// XR_253508 /// XR_430727 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 217226_s_at M95929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M95929.1 /DEF=Human homeobox protein (PHOX1) mRNA, 3 end. /FEA=mRNA /GEN=PHOX1 /PROD=homeobox protein /DB_XREF=gi:189946 /UG=Hs.155606 paired mesoderm homeo box 1 M95929 sideroflexin 3 SFXN3 81855 NM_030971 /// XR_428720 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 217227_x_at X93006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X93006.1 /DEF=H.sapiens mRNA for IgG lambda light chain V-J-C region (clone Tgl11). /FEA=mRNA /PROD=immunoglobulin lambda light chain VJC region /DB_XREF=gi:1070333 /UG=Hs.248030 H.sapiens mRNA for IgG lambda light chain V-J-C region (clone Tgl11) X93006 immunoglobulin lambda variable 1-44 IGLV1-44 28823 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217228_s_at AC003079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003079 /DEF=Human BAC clone GS1-303P24 from 7q21-22 /FEA=CDS /DB_XREF=gi:2588629 /UG=Hs.248062 ASB-4 protein AC003079 ankyrin repeat and SOCS box containing 4 ASB4 51666 NM_016116 /// NM_145872 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from electronic annotation /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 217229_at AC003079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003079 /DEF=Human BAC clone GS1-303P24 from 7q21-22 /FEA=CDS /DB_XREF=gi:2588629 /UG=Hs.248062 ASB-4 protein AC003079 ankyrin repeat and SOCS box containing 4 ASB4 51666 NM_016116 /// NM_145872 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from electronic annotation /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 217230_at AF199015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF199015.1 /DEF=Homo sapiens cytovillin 2 (VIL2) mRNA, partial cds. /FEA=mRNA /GEN=VIL2 /PROD=cytovillin 2 /DB_XREF=gi:6457377 /UG=Hs.155191 villin 2 (ezrin) AF199015 ezrin EZR 7430 NM_001111077 /// NM_003379 /// XM_006715561 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction 0001726 // ruffle // inferred from direct assay /// 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030315 // T-tubule // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044393 // microspike // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation /// 0097454 // Schwann cell microvillus // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 217231_s_at AD000092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AD000092 /DEF=Homo sapiens DNA from chromosome 19p13.2 cosmids R31240, R30272 and R28549 containing the EKLF, GCDH, CRTC, and RAD23A genes, genomic sequence /FEA=CDS_2 /DB_XREF=gi:1905905 /UG=Hs.227489 KIAA0973 protein AD000092 microtubule associated serine/threonine kinase 1 MAST1 22983 NM_014975 /// XM_005259820 /// XM_006722691 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217232_x_at AF059180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF059180 /DEF=Homo sapiens mutant beta-globin (HBB) gene, complete cds /FEA=mRNA /DB_XREF=gi:4837722 /UG=Hs.155376 hemoglobin, beta AF059180 hemoglobin, beta HBB 3043 NM_000518 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217233_at Z97206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z97206 /DEF=Human DNA sequence from PAC 359N14 on chromosome 6q16.3-6q21. Contains CAF-I pseudogene, polymorphic CA repeat, STS /FEA=CDS /DB_XREF=gi:2578094 /UG=Hs.248061 Human DNA sequence from PAC 359N14 on chromosome 6q16.3-6q21. Contains CAF-I pseudogene, polymorphic CA repeat, STS Z97206 RP3-359N14.1 217234_s_at AF199015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF199015.1 /DEF=Homo sapiens cytovillin 2 (VIL2) mRNA, partial cds. /FEA=mRNA /GEN=VIL2 /PROD=cytovillin 2 /DB_XREF=gi:6457377 /UG=Hs.155191 villin 2 (ezrin) AF199015 ezrin EZR 7430 NM_001111077 /// NM_003379 /// XM_006715561 0002066 // columnar/cuboidal epithelial cell development // inferred from sequence or structural similarity /// 0002066 // columnar/cuboidal epithelial cell development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010966 // regulation of phosphate transport // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030154 // cell differentiation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from electronic annotation /// 0032006 // regulation of TOR signaling // inferred from direct assay /// 0035088 // establishment or maintenance of apical/basal cell polarity // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0030315 // T-tubule // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0044393 // microspike // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097449 // astrocyte projection // inferred from electronic annotation /// 0097454 // Schwann cell microvillus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042289 // MHC class II protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 217235_x_at D84140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D84140.1 /DEF=Human immunoglobulin (mAb56) light chain V region mRNA, partial sequence. /FEA=mRNA /PROD=immunoglobulin light chain V-J region /DB_XREF=gi:1255610 /UG=Hs.248043 Human immunoglobulin (mAb56) light chain V region mRNA, partial sequence D84140 immunoglobulin lambda-like polypeptide 5 IGLL5 100423062 NM_001178126 /// NM_001256296 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217236_x_at S74639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S74639.1 /DEF=Ig VH4=Ig heavy chain variable region {clone C20} human, systemic lupus erythematosus, mRNA Partial, 405 nt. /FEA=mRNA /GEN=Ig VH4 /PROD=Ig heavy chain variable region /DB_XREF=gi:807023 /UG=Hs.248035 Ig VH4 S74639 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant delta /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGH /// IGHA1 /// IGHA2 /// IGHD /// IGHG1 /// IGHG3 /// IGHG4 /// IGHM /// IGHV4-31 3492 /// 3493 /// 3494 /// 3495 /// 3500 /// 3502 /// 3503 /// 3507 /// 28396 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217237_at Y10615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y10615 /DEF=H.sapiens CYRN2 gene /FEA=CDS /DB_XREF=gi:2198472 /UG=Hs.248103 a disintegrin and metalloproteinase domain 3b (cyritestin 2) Y10615 /// ADAM metallopeptidase domain 3B (pseudogene) ADAM3B /// ADAM3B 217238_s_at AK026411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026411.1 /DEF=Homo sapiens cDNA: FLJ22758 fis, clone KAIA0811, highly similar to HUMALDB Human aldolase B mRNA. /FEA=mRNA /DB_XREF=gi:10439268 /UG=Hs.234234 aldolase B, fructose-bisphosphate AK026411 aldolase B, fructose-bisphosphate ALDOB 229 NM_000035 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006001 // fructose catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006116 // NADH oxidation // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0070072 // vacuolar proton-transporting V-type ATPase complex assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // not recorded /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from direct assay /// 0070061 // fructose binding // inferred from mutant phenotype 217239_x_at AF044592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF044592 /DEF=Homo sapiens lymphocyte-predominant Hodgkins disease case 4 immunoglobulin heavy chain gene, variable region, partial cds /FEA=CDS /DB_XREF=gi:2852420 /UG=Hs.248077 Homo sapiens lymphocyte-predominant Hodgkins disease case 4 immunoglobulin heavy chain gene, variable region, partial cds AF044592 uncharacterized LOC101930405 LOC101930405 101930405 XM_005275748 217240_at AL049634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049634 /DEF=Human DNA sequence from clone RP4-576H24 on chromosome 20 Contains a pseudogene similar to PTPNS1 (protein tyrosine phosphatase, non-receptortype substrate 1 (Signal Regulatory Protein alpha-1, SIRP, SHPS1, MYD-1)), the gene for SIRP-beta1 (Signal... /FEA=mRNA_4 /DB_XREF=gi:5002686 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 AL049634 signal-regulatory protein beta 1 SIRPB1 10326 NM_001083910 /// NM_001135844 /// NM_006065 /// XM_005260641 /// XM_005260643 /// XM_005260644 /// XM_006710250 /// XM_006723535 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217242_at U20648 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U20648.1 /DEF=Human zinc finger protein (ZNF154) mRNA, partial cds. /FEA=mRNA /GEN=ZNF154 /PROD=zinc finger protein /DB_XREF=gi:676874 /UG=Hs.158299 zinc finger protein 154 (pHZ-92) U20648 zinc finger protein 154 ZNF154 7710 NM_001085384 /// NM_003444 /// NR_110974 /// NR_110975 /// XM_006723364 /// XR_243957 /// XR_430210 /// XR_430211 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217244_at AL021327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021327 /DEF=Human DNA sequence from PAC 124O9 on chromosome 6q21. Contains DNAJ2 (HDJ1) like pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:2804157 /UG=Hs.248071 Human DNA sequence from PAC 124O9 on chromosome 6q21. Contains DNAJ2 (HDJ1) like pseudogene, ESTs, STSs and GSSs AL021327 DnaJ (Hsp40) homolog, subfamily A, member 1 pseudogene 4 /// DNAJA1P4 /// DNAJA1P4 217245_at L22650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L22650.1 /DEF=Human early lymphoid activation protein (EPAG) mRNA sequence. /FEA=mRNA /PROD=early lymphoid activation protein /DB_XREF=gi:468321 /UG=Hs.157431 early lymphoid activation protein L22650 DIAPH2 antisense RNA 1 DIAPH2-AS1 10824 XM_926826 0007165 // signal transduction // non-traceable author statement 0004871 // signal transducer activity // non-traceable author statement 217246_s_at L22650 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L22650.1 /DEF=Human early lymphoid activation protein (EPAG) mRNA sequence. /FEA=mRNA /PROD=early lymphoid activation protein /DB_XREF=gi:468321 /UG=Hs.157431 early lymphoid activation protein L22650 diaphanous-related formin 2 DIAPH2 1730 NM_006729 /// NM_007309 0000910 // cytokinesis // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 217247_at Z98751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98751 /DEF=Human DNA sequence from PAC 560B9 on chromosome 1q24-1q25. Contains profilin-like pseudogene, 60S ribosomal protein L4 pseudogene RNA binding protein, ESTs, GSS /FEA=CDS /DB_XREF=gi:2814366 /UG=Hs.248070 Human DNA sequence from PAC 560B9 on chromosome 1q24-1q25. Contains profilin-like pseudogene, 60S ribosomal protein L4 pseudogene RNA binding protein, ESTs, GSS Z98751 RP4-560B9.4 217248_s_at AL365343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL365343.2 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 32539. /FEA=mRNA /DB_XREF=gi:9187598 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 AL365343 solute carrier family 7 (amino acid transporter light chain, L system), member 8 SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 217249_x_at AC004544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004544 /DEF=Homo sapiens BAC clone CTB-162B4 from 4 /FEA=CDS /DB_XREF=gi:3041843 /UG=Hs.248095 Homo sapiens BAC clone CTB-162B4 from 4 AC004544 /// cytochrome c oxidase subunit VIIa polypeptide 2 (liver) pseudogene 2 COX7A2P2 /// COX7A2P2 217250_s_at AL110281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110281.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K213 (from clone DKFZp434K213). /FEA=mRNA /DB_XREF=gi:5817206 /UG=Hs.158291 KIAA0444 protein AL110281 chromodomain helicase DNA binding protein 5 CHD5 26038 NM_015557 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035093 // spermatogenesis, exchange of chromosomal proteins // inferred from sequence or structural similarity /// 0043967 // histone H4 acetylation // inferred from sequence or structural similarity /// 0060850 // regulation of transcription involved in cell fate commitment // inferred from mutant phenotype /// 0098532 // histone H3-K27 trimethylation // inferred from mutant phenotype /// 1901798 // positive regulation of signal transduction by p53 class mediator // inferred from sequence or structural similarity 0000792 // heterochromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061628 // H3K27me3 modified histone binding // inferred from direct assay 217251_x_at AF043583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043583.1 /DEF=Homo sapiens clone ASMneg1-b3 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865477 /UG=Hs.248083 Homo sapiens clone ASMneg1-b3 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043583 217252_at U46752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U46752.1 /DEF=Human phosphotyrosine independent ligand p62B B-cell isoform for the Lck SH2 domain mRNA, partial cds. /FEA=mRNA /PROD=phosphotyrosine independent ligand p62B for theLck SH2 domain B-cell isoform /DB_XREF=gi:1184950 /UG=Hs.158298 oxidative stress induced like U46752 0005829 // cytosol // non-traceable author statement 0008270 // zinc ion binding // inferred from electronic annotation 217253_at L37198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L37198.1 /DEF=Homo sapiens (clone B3B3E13) Huntingtons disease candidate region mRNA fragment. /FEA=mRNA /DB_XREF=gi:600519 /UG=Hs.233617 Homo sapiens (clone B3B3E13) Huntingtons disease candidate region mRNA fragment L37198 SH3-domain binding protein 2 SH3BP2 6452 NM_001122681 /// NM_001145855 /// NM_001145856 /// NM_003023 /// XM_005247997 /// XM_005247998 /// XM_005247999 /// XM_005248000 /// XM_006713911 /// XM_006713912 /// XM_006713913 0007165 // signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 217254_s_at AF053356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF053356 /DEF=Homo sapiens chromosome 7q22 sequence /FEA=mRNA_15 /DB_XREF=gi:3135305 /UG=Hs.2303 erythropoietin AF053356 erythropoietin EPO 2056 NM_000799 0001666 // response to hypoxia // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0042541 // hemoglobin biosynthetic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071474 // cellular hyperosmotic response // inferred from direct assay /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from direct assay /// 1902251 // negative regulation of erythrocyte apoptotic process // inferred from direct assay /// 2001258 // negative regulation of cation channel activity // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from electronic annotation 217255_at U46752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U46752.1 /DEF=Human phosphotyrosine independent ligand p62B B-cell isoform for the Lck SH2 domain mRNA, partial cds. /FEA=mRNA /PROD=phosphotyrosine independent ligand p62B for theLck SH2 domain B-cell isoform /DB_XREF=gi:1184950 /UG=Hs.158298 oxidative stress induced like U46752 0005829 // cytosol // non-traceable author statement 0008270 // zinc ion binding // inferred from electronic annotation 217256_x_at Z98950 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z98950 /DEF=Human DNA sequence from PAC 507I15 on chromosome Xq26.3-27.3. Contains 60S ribosomal protein L44 (L41, L36) like gene, ESTs, STSs and a polymorphic CA repeat /FEA=CDS /DB_XREF=gi:3036783 /UG=Hs.248094 Human DNA sequence from PAC 507I15 on chromosome Xq26.3-27.3. Contains 60S ribosomal protein L44 (L41, L36) like gene, ESTs, STSs and a polymorphic CA repeat Z98950 RP3-507I15.1 217257_at L37198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L37198.1 /DEF=Homo sapiens (clone B3B3E13) Huntingtons disease candidate region mRNA fragment. /FEA=mRNA /DB_XREF=gi:600519 /UG=Hs.233617 Homo sapiens (clone B3B3E13) Huntingtons disease candidate region mRNA fragment L37198 SH3-domain binding protein 2 SH3BP2 6452 NM_001122681 /// NM_001145855 /// NM_001145856 /// NM_003023 /// XM_005247997 /// XM_005247998 /// XM_005247999 /// XM_005248000 /// XM_006713911 /// XM_006713912 /// XM_006713913 0007165 // signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 217258_x_at AF043583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF043583.1 /DEF=Homo sapiens clone ASMneg1-b3 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds. /FEA=mRNA /GEN=IGL /PROD=immunoglobulin lambda chain /DB_XREF=gi:2865477 /UG=Hs.248083 Homo sapiens clone ASMneg1-b3 immunoglobulin lambda chain VJ region, (IGL) mRNA, partial cds AF043583 immunoglobulin lambda variable 1-44 IGLV1-44 28823 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0050776 // regulation of immune response // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217259_at AL117549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117549.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H0123 (from clone DKFZp586H0123). /FEA=mRNA /DB_XREF=gi:5912083 /UG=Hs.268496 Homo sapiens mRNA; cDNA DKFZp586H0123 (from clone DKFZp586H0123) AL117549 217260_x_at AJ239383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ239383.1 /DEF=Homo sapiens mRNA for immunoglobulin heavy chain variable region, ID 31. /FEA=mRNA /GEN=IGHV /PROD=immunoglobulin heavy chain variable region /DB_XREF=gi:4456587 /UG=Hs.249245 Homo sapiens mRNA for single-chain antibody, complete cds AJ239383 uncharacterized LOC102723479 LOC102723479 102723479 XR_424566 /// XR_429429 /// XR_430709 /// XR_433045 217261_at AF000991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF000991.1 /DEF=Homo sapiens testis-specific Testis Transcript Y 2 (TTY2) mRNA, partial cds. /FEA=mRNA /GEN=TTY2 /PROD=testis-specific Testis Transcript Y 2 /DB_XREF=gi:2580567 /UG=Hs.158345 testis-specific testis transcript Y 2 AF000991 testis-specific transcript, Y-linked 2 (non-protein coding) /// testis-specific transcript, Y-linked 2B (non-protein coding) TTTY2 /// TTTY2B 60439 /// 100101117 NR_001536 /// NR_003590 217262_s_at BC000059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000059.1 /DEF=Homo sapiens, clone IMAGE:3506648, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3506648) /DB_XREF=gi:12652626 /UG=Hs.252387 cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog BC000059 cadherin, EGF LAG seven-pass G-type receptor 1 CELSR1 9620 NM_014246 /// XM_006724383 0001736 // establishment of planar polarity // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042249 // establishment of planar polarity of embryonic epithelium // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0048105 // establishment of body hair planar orientation // inferred from electronic annotation /// 0060488 // orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060489 // planar dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060490 // lateral sprouting involved in lung morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090251 // protein localization involved in establishment of planar polarity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // non-traceable author statement 217263_x_at S76346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S76346.1 /DEF=AML1=AML1 {alternatively spliced, exons 5 and b} human, mRNA Partial, 284 nt. /FEA=mRNA /GEN=AML1 /PROD=AML1 /DB_XREF=gi:913288 /UG=Hs.166060 AML1 S76346 uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1 LOC100506403 /// LOC101928269 /// RUNX1 861 /// 100506403 /// 101928269 NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 217264_s_at U81961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U81961 /DEF=Homo sapiens amiloride-sensitive epithelial sodium channel alpha subunit alpha ENaC-1 and alpha ENaC-2 (SCNN1A) genes, alternatively spliced, promoter region and partial cds /FEA=CDS_3 /DB_XREF=gi:11863173 /UG=Hs.2794 sodium channel, nonvoltage-gated 1 alpha U81961 sodium channel, non-voltage-gated 1 alpha subunit SCNN1A 6337 NM_001038 /// NM_001159575 /// NM_001159576 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0034706 // sodium channel complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 217265_at AL020989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL020989 /DEF=Human DNA sequence from clone RP1-192P9 on chromosome Xp11.23-11.4 Contains a pseudogene similar to rat Plasmolipin, ESTs and GSSs /FEA=CDS /DB_XREF=gi:4539519 /UG=Hs.249209 Human DNA sequence from clone RP1-192P9 on chromosome Xp11.23-11.4 Contains a pseudogene similar to rat Plasmolipin, ESTs and GSSs AL020989 RP1-192P9.1 217266_at Z97353 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z97353 /DEF=Human DNA sequence from clone RP1-90L6 on chromosome 22q11.21-11.23 Contains an RPL15 (60S Ribosomal Protein L15) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:4455632 /UG=Hs.247851 Human DNA sequence from clone RP1-90L6 on chromosome 22q11.21-11.23 Contains an RPL15 (60S Ribosomal Protein L15) pseudogene, ESTs, STSs and GSSs Z97353 ribosomal protein L15 RPL15 6138 NM_001253379 /// NM_001253380 /// NM_001253382 /// NM_001253383 /// NM_001253384 /// NM_002948 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217267_s_at AK024417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024417.1 /DEF=Homo sapiens cDNA FLJ14355 fis, clone Y79AA1001875, moderately similar to RAS-RELATED PROTEIN RAB-7. /FEA=mRNA /DB_XREF=gi:10436805 /UG=Hs.237955 hypothetical protein PRO2706 AK024417 RAB7A, member RAS oncogene family RAB7A 7879 NM_004637 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0007174 // epidermal growth factor catabolic process // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 0090383 // phagosome acidification // inferred from mutant phenotype /// 0090385 // phagosome-lysosome fusion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 217268_at AK024417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024417.1 /DEF=Homo sapiens cDNA FLJ14355 fis, clone Y79AA1001875, moderately similar to RAS-RELATED PROTEIN RAB-7. /FEA=mRNA /DB_XREF=gi:10436805 /UG=Hs.237955 hypothetical protein PRO2706 AK024417 RAB7A, member RAS oncogene family RAB7A 7879 NM_004637 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0007174 // epidermal growth factor catabolic process // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement /// 0090383 // phagosome acidification // inferred from mutant phenotype /// 0090385 // phagosome-lysosome fusion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation 217269_s_at AP001672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AP001672 /DEF=Homo sapiens genomic DNA, chromosome 21q, section 16105 /FEA=CDS /DB_XREF=gi:7768762 /UG=Hs.158333 protease, serine, 7 (enterokinase) AP001672 transmembrane protease, serine 15 TMPRSS15 5651 NM_002772 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217270_s_at AC005393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005393 /DEF=Homo sapiens chromosome 19, CIT-HSP BAC 470n8 /FEA=CDS_1 /DB_XREF=gi:3399665 /UG=Hs.249140 Homo sapiens chromosome 19, CIT-HSP BAC 470n8 AC005393 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B DYRK1B 9149 NM_004714 /// NM_006483 /// NM_006484 /// XM_005259395 /// XM_005259398 /// XM_006723464 /// XM_006723465 0006468 // protein phosphorylation // inferred from direct assay /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217271_at AF011499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF011499 /DEF=Homo sapiens GTP-binding protein alpha 11 subunit pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:2331129 /UG=Hs.249119 Homo sapiens GTP-binding protein alpha 11 subunit pseudogene, complete sequence AF011499 GS1-124K5.9 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005525 // GTP binding // non-traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 217272_s_at AJ001698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001698.1 /DEF=Homo sapiens mRNA for hurpin, clone R7-16.1. /FEA=mRNA /GEN=PI13 /PROD=hurpin /DB_XREF=gi:6018509 /UG=Hs.241407 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 AJ001698 serpin peptidase inhibitor, clade B (ovalbumin), member 13 SERPINB13 5275 NM_012397 /// XM_005266705 /// XM_005266707 0009411 // response to UV // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0030162 // regulation of proteolysis // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 217273_at AL022101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022101 /DEF=Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contain... /FEA=CDS_1 /DB_XREF=gi:3171895 /UG=Hs.251419 Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contains ESTs, AL022101 PRAME family member 10 PRAMEF10 343071 NM_001039361 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0042974 // retinoic acid receptor binding // inferred from electronic annotation 217274_x_at X52005 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52005.1 /DEF=H.sapiens skeletal embryonic myosin light chain 1 (MLC1) mRNA. /FEA=mRNA /GEN=MCL1 /PROD=myosin light chain 1 /DB_XREF=gi:34677 /UG=Hs.159218 H.sapiens skeletal embryonic myosin light chain 1 (MLC1) mRNA X52005 myosin, light chain 4, alkali; atrial, embryonic MYL4 4635 NM_001002841 /// NM_002476 /// XM_005257391 /// XM_005257392 0002026 // regulation of the force of heart contraction // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005829 // cytosol // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0031672 // A band // inferred from mutant phenotype 0003785 // actin monomer binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0032038 // myosin II heavy chain binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from mutant phenotype 217275_at L77565 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L77565.1 /DEF=Homo sapiens DGS-H mRNA, 3 end. /FEA=mRNA /DB_XREF=gi:1377763 /UG=Hs.250168 DiGeorge syndrome gene H L77565 testis-specific serine kinase 2 TSSK2 23617 NM_053006 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217276_x_at AL590118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL590118.1 /DEF=Novel human mRNA from chromosome 22. Splice variant of dJ222E13.C22.1. /FEA=CDS /PROD=hypothetical protein /DB_XREF=gi:13445181 /UG=Hs.239934 CGI-96 protein AL590118 serine hydrolase-like 2 SERHL2 253190 NM_001284334 /// NM_014509 /// NR_104300 /// NR_104301 /// XM_006724222 /// XR_244363 /// XR_430405 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 217277_at AL008721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL008721 /DEF=Human DNA sequence from clone CTA-390C10 on chromosome 22q11.21-12.1 Contains an Immunoglobulin-like gene and a pseudogene similar to Beta Crystallin, ESTs, STSs, GSSs and taga and tat repeat polymorphisms /FEA=mRNA /DB_XREF=gi:3171883 /UG=Hs.158352 Human DNA sequence from clone CTA-390C10 on chromosome 22q11.21-12.1 Contains an Immunoglobulin-like gene and a pseudogene similar to Beta Crystallin, ESTs, STSs, GSSs and taga and tat repeat polymorphisms AL008721 immunoglobulin lambda variable (IV)/OR22-1 (pseudogene) /// IGLVIVOR22-1 /// IGLVIVOR22-1 217278_x_at AF023203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF023203.1 /DEF=Homo sapiens homeobox protein Og12 (OGL12) mRNA, partial cds. /FEA=mRNA /GEN=OGL12 /PROD=homeobox protein Og12 /DB_XREF=gi:2979681 /UG=Hs.158350 Homo sapiens homeobox protein Og12 (OGL12) mRNA, partial cds AF023203 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003170 // heart valve development // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217279_x_at X83535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X83535.1 /DEF=Homo sapiens mRNA for membrane-type matrix metalloproteinase. /FEA=mRNA /GEN=human 29 /PROD=MT-MMP /DB_XREF=gi:804993 /UG=Hs.2399 matrix metalloproteinase 14 (membrane-inserted) X83535 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217280_x_at AF061785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF061785 /DEF=Homo sapiens gamma-aminobutyric acid receptor A5 subunit (GABRA5) gene, three alternative first exons and exons 2-3, partial cds /FEA=CDS_1 /DB_XREF=gi:3420025 /UG=Hs.24969 gamma-aminobutyric acid (GABA) A receptor, alpha 5 AF061785 gamma-aminobutyric acid (GABA) A receptor, alpha 5 GABRA5 2558 NM_000810 /// NM_001165037 /// XM_005268258 /// XM_006720459 0001662 // behavioral fear response // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 217281_x_at AJ239383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ239383.1 /DEF=Homo sapiens mRNA for immunoglobulin heavy chain variable region, ID 31. /FEA=mRNA /GEN=IGHV /PROD=immunoglobulin heavy chain variable region /DB_XREF=gi:4456587 /UG=Hs.249245 Homo sapiens mRNA for single-chain antibody, complete cds AJ239383 immunoglobulin heavy locus /// immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant alpha 2 (A2m marker) /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 /// uncharacterized LOC102725526 IGH /// IGHA1 /// IGHA2 /// IGHG1 /// IGHG2 /// IGHG3 /// IGHM /// IGHV4-31 /// LOC102725526 3492 /// 3493 /// 3494 /// 3500 /// 3501 /// 3502 /// 3507 /// 28396 /// 102725526 XR_425424 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217282_at AK001970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001970.1 /DEF=Homo sapiens cDNA FLJ11108 fis, clone PLACE1005804, highly similar to Homo sapiens alpha 1,2-mannosidase IB mRNA. /FEA=mRNA /DB_XREF=gi:7023566 /UG=Hs.239114 mannosidase, alpha, class 1A, member 2 AK001970 mannosidase, alpha, class 1A, member 2 MAN1A2 10905 NM_006699 /// XM_006710302 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 217283_at AF023203 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF023203.1 /DEF=Homo sapiens homeobox protein Og12 (OGL12) mRNA, partial cds. /FEA=mRNA /GEN=OGL12 /PROD=homeobox protein Og12 /DB_XREF=gi:2979681 /UG=Hs.158350 Homo sapiens homeobox protein Og12 (OGL12) mRNA, partial cds AF023203 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003170 // heart valve development // inferred from electronic annotation /// 0003209 // cardiac atrium morphogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060415 // muscle tissue morphogenesis // inferred from electronic annotation /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217284_x_at AL589866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL589866.1 /DEF=Novel human mRNA from chromosome 22. /FEA=CDS /PROD=hypothetical protein /DB_XREF=gi:13374128 /UG=Hs.239934 CGI-96 protein AL589866 serine hydrolase-like 2 SERHL2 253190 NM_001284334 /// NM_014509 /// NR_104300 /// NR_104301 /// XM_006724222 /// XR_244363 /// XR_430405 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 217285_at L77565 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L77565.1 /DEF=Homo sapiens DGS-H mRNA, 3 end. /FEA=mRNA /DB_XREF=gi:1377763 /UG=Hs.250168 DiGeorge syndrome gene H L77565 DiGeorge syndrome critical region gene 14 /// testis-specific serine kinase 2 DGCR14 /// TSSK2 8220 /// 23617 NM_022719 /// NM_053006 /// XM_005261282 /// XM_006724329 /// XM_006724330 /// XM_006724331 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217286_s_at BC001805 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001805.1 /DEF=Homo sapiens, clone IMAGE:3543670, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3543670) /DB_XREF=gi:12804742 /UG=Hs.240615 hypothetical protein FLJ13556 similar to N-myc downstream regulated 3 BC001805 NDRG family member 3 NDRG3 57446 NM_022477 /// NM_032013 /// NR_038370 /// XM_006723837 /// XM_006723838 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 217287_s_at AJ271068 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ271068.1 /DEF=Homo sapiens mRNA for transient receptor potential channel 6, variant delta377-431 (TRP6 gene). /FEA=CDS /GEN=TRP6 /PROD=transient receptor potential channel 6, variantdelta377-431 /DB_XREF=gi:9716912 /UG=Hs.159003 transient receptor potential channel 6 AJ271068 transient receptor potential cation channel, subfamily C, member 6 TRPC6 7225 NM_004621 /// XM_006718898 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032414 // positive regulation of ion transmembrane transporter activity // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay 217288_at AL049983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049983.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D042 (from clone DKFZp564D042). /FEA=mRNA /DB_XREF=gi:4884234 /UG=Hs.240136 Homo sapiens mRNA; cDNA DKFZp564D042 (from clone DKFZp564D042) AL049983 217289_s_at AF097831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF097831 /DEF=Homo sapiens glucose-6-phosphate transporter (G6PT) gene, G6PT-Dt allele, complete cds /FEA=CDS /DB_XREF=gi:4406199 /UG=Hs.242 glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) AF097831 solute carrier family 37 (glucose-6-phosphate transporter), member 4 SLC37A4 2542 NM_001164277 /// NM_001164278 /// NM_001164279 /// NM_001164280 /// NM_001467 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from direct assay /// 0015760 // glucose-6-phosphate transport // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032682 // negative regulation of chemokine production // inferred from electronic annotation /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045730 // respiratory burst // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from direct assay /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from mutant phenotype 217290_at AL030995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL030995 /DEF=Human DNA sequence from clone 1170D6 on chromosome Xq22.3-23. Contains a pseudogene similar to U-SNRNP_associated Cyclophilin (USA-CYP, EC 5.2.1.8), ESTs, an STS and a GSS /FEA=CDS /DB_XREF=gi:3650302 /UG=Hs.247752 Human DNA sequence from clone 1170D6 on chromosome Xq22.3-23. Contains a pseudogene similar to U-SNRNP_associated Cyclophilin (USA-CYP, EC 5.2.1.8), ESTs, an STS and a GSS AL030995 RP5-1170D6.1 217291_at Z21818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z21818 /DEF=H.sapiens carcinoembryonic antigen gene /FEA=mRNA /DB_XREF=gi:437783 /UG=Hs.166040 H.sapiens carcinoembryonic antigen gene Z21818 carcinoembryonic antigen-related cell adhesion molecule 5 CEACAM5 1048 NM_001291484 /// NM_004363 /// XM_005258413 /// XM_005258415 0010832 // negative regulation of myotube differentiation // inferred from direct assay /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071575 // integral component of external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0034235 // GPI anchor binding // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 217292_at AL117549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117549.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H0123 (from clone DKFZp586H0123). /FEA=mRNA /DB_XREF=gi:5912083 /UG=Hs.268496 Homo sapiens mRNA; cDNA DKFZp586H0123 (from clone DKFZp586H0123) AL117549 myotubularin related protein 7 MTMR7 9108 NM_004686 /// XM_006716414 0006470 // protein dephosphorylation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 217293_at AF209975 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF209975.1 /DEF=Homo sapiens tissue-type aorta mRNA sequence. /FEA=mRNA /DB_XREF=gi:12246902 /UG=Hs.2463 angiopoietin 1 AF209975 217294_s_at U88968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U88968.1 /DEF=Human alpha enolase like 1 (ENO1L1) mRNA, partial cds. /FEA=mRNA /GEN=ENO1L1 /PROD=alpha enolase like 1 /DB_XREF=gi:3282242 /UG=Hs.254105 enolase 1, (alpha) U88968 enolase 1, (alpha) ENO1 2023 NM_001201483 /// NM_001428 /// XM_006710433 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217295_at U14383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U14383.1 /DEF=Human mucin (MUC8) mRNA, partial cds. /FEA=mRNA /GEN=MUC8 /PROD=mucin /DB_XREF=gi:606953 /UG=Hs.1607 mucin 8, tracheobronchial U14383 mucin 8 MUC8 100129528 XM_005266194 /// XM_005275730 /// XM_005276431 217296_at AF135564 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF135564.1 /DEF=Homo sapiens p50 killer cell activating receptor KAR-K1d mRNA, alternatively spliced, partial cds. /FEA=mRNA /PROD=p50 killer cell activating receptor KAR-K1d /DB_XREF=gi:5730901 /UG=Hs.258612 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 AF135564 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 KIR2DS1 3806 NM_014512 /// XM_006725422 /// XM_006725423 /// XM_006725431 /// XM_006725432 /// XM_006725433 /// XM_006725439 /// XM_006725440 /// XM_006725642 /// XM_006725643 /// XM_006725657 /// XM_006725658 /// XM_006725659 /// XM_006725665 /// XM_006725666 /// XM_006725792 /// XM_006725793 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0030110 // HLA-C specific inhibitory MHC class I receptor activity // non-traceable author statement 217297_s_at AF143684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF143684.1 /DEF=Homo sapiens unconventional myosin IXb (MYO9b) mRNA, partial cds. /FEA=mRNA /GEN=MYO9b /PROD=unconventional myosin IXb /DB_XREF=gi:6002742 /UG=Hs.159629 myosin IXB AF143684 myosin IXB MYO9B 4650 NM_001130065 /// NM_004145 /// XM_005259915 /// XM_006722755 /// XM_006722756 /// XM_006722757 /// XM_006722758 0002548 // monocyte chemotaxis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030048 // actin filament-based movement // traceable author statement /// 0032011 // ARF protein signal transduction // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0032433 // filopodium tip // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 217298_at M13934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M13934 /DEF=Human ribosomal protein S14 gene, complete cds /FEA=CDS_2 /DB_XREF=gi:337498 /UG=Hs.244621 ribosomal protein S14 M13934 ribosomal protein S14 RPS14 6208 NM_001025070 /// NM_001025071 /// NM_005617 /// XM_006714790 0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000028 // ribosomal small subunit assembly // inferred from sequence or structural similarity /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from sequence or structural similarity /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 217299_s_at AK001017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001017.1 /DEF=Homo sapiens cDNA FLJ10155 fis, clone HEMBA1003433, highly similar to Homo sapiens gene for NBS1. /FEA=mRNA /DB_XREF=gi:7022031 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) AK001017 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 217300_at U80771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80771.1 /DEF=Human EST clone 25267 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2231374 /UG=Hs.245410 Human EST clone 25267 mariner transposon Hsmar1 sequence U80771 217301_x_at X71810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X71810.1 /DEF=H.sapiens IEF 9306 mRNA. /FEA=mRNA /GEN=9306 /PROD=IEF SSP 9306 /DB_XREF=gi:297905 /UG=Hs.16003 retinoblastoma-binding protein 4 X71810 retinoblastoma binding protein 4 RBBP4 5928 NM_001135255 /// NM_001135256 /// NM_005610 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006334 // nucleosome assembly // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016580 // Sin3 complex // non-traceable author statement /// 0016581 // NuRD complex // inferred from direct assay /// 0016581 // NuRD complex // non-traceable author statement /// 0016589 // NURF complex // inferred from direct assay /// 0033186 // CAF-1 complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042393 // histone binding // non-traceable author statement /// 0042826 // histone deacetylase binding // inferred from physical interaction 217302_at AC004853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004853 /DEF=Homo sapiens PAC clone RP4-669B10 from 7q33-q35 /FEA=CDS_3 /DB_XREF=gi:3766130 /UG=Hs.159899 Homo sapiens PAC clone RP4-669B10 from 7q33-q35 AC004853 olfactory receptor, family 2, subfamily F, member 2 OR2F2 135948 NM_001004685 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 217303_s_at X70812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X70812 /DEF=H.sapiens gene for beta 3 adrenergic receptor /FEA=mRNA_2 /DB_XREF=gi:312398 /UG=Hs.2549 adrenergic, beta-3-, receptor X70812 adrenoceptor beta 3 ADRB3 155 NM_000025 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0002025 // vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002032 // desensitization of G-protein coupled receptor protein signaling pathway by arrestin // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0031649 // heat generation // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from direct assay /// 0071875 // adrenergic receptor signaling pathway // inferred from electronic annotation /// 0071875 // adrenergic receptor signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004935 // adrenergic receptor activity // inferred from electronic annotation /// 0004939 // beta-adrenergic receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015052 // beta3-adrenergic receptor activity // inferred from mutant phenotype /// 0031699 // beta-3 adrenergic receptor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051379 // epinephrine binding // inferred from electronic annotation /// 0051380 // norepinephrine binding // inferred from direct assay 217304_at Y14488 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y14488.1 /DEF=Homo sapiens mRNA for putative 14kD protein containing SHMT homology, clone pUS1215. /FEA=mRNA /PROD=14 kDa protein /DB_XREF=gi:5830441 /UG=Hs.268495 Homo sapiens mRNA for putative 14kD protein containing SHMT homology, clone pUS1215 Y14488 serine hydroxymethyltransferase 1 (soluble) SHMT1 6470 NM_001281786 /// NM_004169 /// NM_148918 /// XM_005256767 0006508 // proteolysis // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006565 // L-serine catabolic process // inferred from direct assay /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009113 // purine nucleobase biosynthetic process // inferred from direct assay /// 0019264 // glycine biosynthetic process from serine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from direct assay /// 0046655 // folic acid metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004372 // glycine hydroxymethyltransferase activity // inferred from direct assay /// 0004372 // glycine hydroxymethyltransferase activity // traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0008732 // L-allo-threonine aldolase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 217305_s_at AL035122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035122.1 /DEF=H.sapiens gene from PACs 295C6 and 313L4. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:4153950 /UG=Hs.163045 soluble adenylyl cyclase AL035122 adenylate cyclase 10 (soluble) ADCY10 55811 NM_001167749 /// NM_018417 /// XM_005245329 /// XM_005245330 /// XM_006711449 0006171 // cAMP biosynthetic process // non-traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 217306_at AL031119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031119 /DEF=Human DNA sequence from clone 28C20 on chromosome 6q24. Contains a Zinc Finger gene ZNF131 pseudogene, ESTs an STS and GSSs /FEA=CDS /DB_XREF=gi:3550036 /UG=Hs.247751 Human DNA sequence from clone 28C20 on chromosome 6q24. Contains a Zinc Finger gene ZNF131 pseudogene, ESTs an STS and GSSs AL031119 RP1-28C20.1 217307_at AF086790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF086790.1 /DEF=Homo sapiens aconitase precursor (ACON) mRNA, nuclear gene encoding mitochondrial protein, partial cds. /FEA=mRNA /GEN=ACON /PROD=aconitase precursor /DB_XREF=gi:3600097 /UG=Hs.166002 Homo sapiens aconitase precursor (ACON) mRNA, nuclear gene encoding mitochondrial protein, partial cds AF086790 aconitase 2, mitochondrial ACO2 50 NM_001098 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006101 // citrate metabolic process // inferred from direct assay /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0003994 // aconitate hydratase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 217308_at AJ003145 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ003145.1 /DEF=Homo sapiens mRNA for olfactory receptor protein, pseudogene. /FEA=CDS /GEN=olfmf2 /DB_XREF=gi:2808536 /UG=Hs.247693 olfactory receptor, family 1, subfamily F, member 2 AJ003145 olfactory receptor, family 1, subfamily F, member 2 OR1F2P 26184 NR_002169 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 217309_s_at AJ001867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ001867.1 /DEF=Homo Sapiens mRNA, partial cDNA sequence from cDNA selection, DCR1-11.0. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:2969904 /UG=Hs.26146 Down syndrome critical region gene 3 AJ001867 Down syndrome critical region gene 3 DSCR3 10311 NM_006052 /// XM_005260909 /// XM_005260911 0007034 // vacuolar transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0030904 // retromer complex // inferred from electronic annotation 217310_s_at AK027075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027075.1 /DEF=Homo sapiens cDNA: FLJ23422 fis, clone HEP22556. /FEA=mRNA /DB_XREF=gi:10440105 /UG=Hs.26023 KIAA1041 protein AK027075 forkhead box J3 FOXJ3 22887 NM_001198850 /// NM_001198851 /// NM_001198852 /// NM_014947 /// XM_005270632 /// XM_006710458 /// XM_006710459 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217311_at AF086790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF086790.1 /DEF=Homo sapiens aconitase precursor (ACON) mRNA, nuclear gene encoding mitochondrial protein, partial cds. /FEA=mRNA /GEN=ACON /PROD=aconitase precursor /DB_XREF=gi:3600097 /UG=Hs.166002 Homo sapiens aconitase precursor (ACON) mRNA, nuclear gene encoding mitochondrial protein, partial cds AF086790 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0003994 // aconitate hydratase activity // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 217312_s_at L23982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L23982 /DEF=Homo sapiens (clones: CW52-2, CW27-6, CW15-2, CW26-5, 11-67) collagen type VII intergenic region and (COL7A1) gene, complete cds /FEA=CDS /DB_XREF=gi:495865 /UG=Hs.1640 collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) L23982 collagen, type VII, alpha 1 COL7A1 1294 NM_000094 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005590 // collagen type VII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 217313_at AC004692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004692 /DEF=Homo sapiens PAC clone RP5-1107K12 from 7p12-p14 /FEA=CDS /DB_XREF=gi:3135282 /UG=Hs.247699 Homo sapiens PAC clone RP5-1107K12 from 7p12-p14 AC004692 AC004692.5 217314_at AC002544 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002544 /DEF=Homo sapiens Chromosome 16 BAC clone CIT987SK-A-761H5 /FEA=CDS_1 /DB_XREF=gi:3337382 /UG=Hs.247723 Homo sapiens Chromosome 16 BAC clone CIT987SK-A-761H5 AC002544 cell division cycle 37 pseudogene 1 /// CDC37P1 /// CDC37P1 217315_s_at AL050220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050220.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J1923 (from clone DKFZp586J1923); partial cds. /FEA=mRNA /GEN=DKFZp586J1923 /PROD=hypothetical protein /DB_XREF=gi:4884461 /UG=Hs.165296 kallikrein 13 AL050220 kallikrein-related peptidase 13 KLK13 26085 NM_015596 0006508 // proteolysis // non-traceable author statement /// 0016485 // protein processing // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030141 // secretory granule // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from direct assay 217316_at AC005255 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005255 /DEF=Homo sapiens chromosome 19, CIT-HSP-146e8 /FEA=CDS_1 /DB_XREF=gi:3289998 /UG=Hs.247716 Homo sapiens chromosome 19, CIT-HSP-146e8 AC005255 olfactory receptor, family 7, subfamily A, member 10 OR7A10 390892 NM_001005190 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 217317_s_at AB002391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB002391.2 /DEF=Homo sapiens mRNA for KIAA0393 protein, partial cds. /FEA=mRNA /GEN=KIAA0393 /PROD=KIAA0393 protein /DB_XREF=gi:6683696 /UG=Hs.266933 hect domain and RLD 2 AB002391 hect domain and RLD 2 pseudogene 2 /// hect domain and RLD 2 pseudogene 9 HERC2P2 /// HERC2P9 400322 /// 440248 NM_199045 /// NR_002824 /// NR_036443 217318_x_at AJ000190 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ000190 /DEF=Homo sapiens p58 NK receptor pseudogene /FEA=CDS /DB_XREF=gi:3287154 /UG=Hs.247714 Homo sapiens p58 NK receptor pseudogene AJ000190 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 /// killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 /// killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 /// killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 /// killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 KIR2DL1 /// KIR2DL2 /// KIR2DL3 /// KIR2DS1 /// KIR2DS2 /// KIR2DS4 3802 /// 3803 /// 3804 /// 3806 /// 3809 /// 100132285 NM_001281971 /// NM_001281972 /// NM_001291695 /// NM_001291696 /// NM_001291700 /// NM_001291701 /// NM_012312 /// NM_012314 /// NM_014218 /// NM_014219 /// NM_014511 /// NM_014512 /// NM_015868 /// XM_005258889 /// XM_005277253 /// XM_005277304 /// XM_005278262 /// XM_006725421 /// XM_006725422 /// XM_006725423 /// XM_006725425 /// XM_006725426 /// XM_006725427 /// XM_006725428 /// XM_006725429 /// XM_006725430 /// XM_006725431 /// XM_006725432 /// XM_006725433 /// XM_006725435 /// XM_006725436 /// XM_006725437 /// XM_006725438 /// XM_006725439 /// XM_006725440 /// XM_006725442 /// XM_006725642 /// XM_006725643 /// XM_006725653 /// XM_006725655 /// XM_006725656 /// XM_006725657 /// XM_006725658 /// XM_006725659 /// XM_006725661 /// XM_006725662 /// XM_006725663 /// XM_006725664 /// XM_006725665 /// XM_006725666 /// XM_006725668 /// XM_006725669 /// XM_006725788 /// XM_006725789 /// XM_006725791 /// XM_006725792 /// XM_006725793 /// XM_006726156 /// XM_006726157 0002769 // natural killer cell inhibitory signaling pathway // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement 0003823 // antigen binding // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030110 // HLA-C specific inhibitory MHC class I receptor activity // non-traceable author statement /// 0032393 // MHC class I receptor activity // non-traceable author statement 217319_x_at AL135960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL135960 /DEF=Human DNA sequence from clone RP1-18D14 on chromosome 1 Contains genes for SIL (TAL1 (SCL) interrupting locus ), TAL1 (T-cell acute lymphocytic leukemia 1), 17 KD membrane associated protein (DD96 protein), CYP4A11 (cytochrome P450, subfamily IVA... /FEA=mRNA_4 /DB_XREF=gi:6635875 /UG=Hs.1645 cytochrome P450, subfamily IVA, polypeptide 11 AL135960 cytochrome P450, family 4, subfamily A, polypeptide 11 /// cytochrome P450, family 4, subfamily A, polypeptide 22 CYP4A11 /// CYP4A22 1579 /// 284541 NM_000778 /// NM_001010969 /// XM_005270537 /// XM_005270538 /// XM_005270539 /// XM_005270767 /// XM_005270768 /// XM_005270769 /// XM_005270770 /// XM_006710392 /// XR_246241 /// XR_246242 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0003091 // renal water homeostasis // inferred from expression pattern /// 0003095 // pressure natriuresis // inferred from expression pattern /// 0006631 // fatty acid metabolic process // traceable author statement /// 0006691 // leukotriene metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // inferred from direct assay /// 0032305 // positive regulation of icosanoid secretion // inferred from mutant phenotype /// 0036101 // leukotriene B4 catabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055078 // sodium ion homeostasis // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008392 // arachidonic acid epoxygenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018685 // alkane 1-monooxygenase activity // inferred from direct assay /// 0018685 // alkane 1-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050051 // leukotriene-B4 20-monooxygenase activity // inferred from direct assay /// 0052869 // arachidonic acid omega-hydroxylase activity // inferred from electronic annotation 217320_at AJ275413 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275413 /DEF=Homo sapiens partial IGVH3 DP29 gene for immunoglobulin heavy chain V region, case 1, cell Mo VII 116 /FEA=CDS /DB_XREF=gi:7573089 /UG=Hs.272364 Homo sapiens partial IGVH3 DP29 gene for immunoglobulin heavy chain V region, case 1, cell Mo VII 116 AJ275413 uncharacterized LOC100293211 LOC100293211 100293211 XM_006710246 0005515 // protein binding // inferred from electronic annotation 217321_x_at U63332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U63332.1 /DEF=Human super cysteine rich protein mRNA, partial cds. /FEA=mRNA /PROD=super cysteine rich protein /DB_XREF=gi:1480862 /UG=Hs.169325 Human super cysteine rich protein mRNA, partial cds U63332 ataxin 3 ATXN3 4287 NM_001024631 /// NM_001127696 /// NM_001127697 /// NM_001164774 /// NM_001164776 /// NM_001164777 /// NM_001164778 /// NM_001164779 /// NM_001164780 /// NM_001164781 /// NM_001164782 /// NM_004993 /// NM_030660 /// NR_028453 /// NR_028454 /// NR_028455 /// NR_028456 /// NR_028457 /// NR_028458 /// NR_028459 /// NR_028460 /// NR_028461 /// NR_028462 /// NR_028463 /// NR_028464 /// NR_028465 /// NR_028466 /// NR_028467 /// NR_028468 /// NR_028469 /// NR_028470 /// NR_031765 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010810 // regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0035520 // monoubiquitinated protein deubiquitination // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004843 // ubiquitin-specific protease activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 217322_x_at AL024509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL024509 /DEF=Human DNA sequence from clone 522P13 on chromosome 6p21.31-22.3. Contains a 60S Ribosomal Protein L21 pseudogene and an HNRNP A3 (Heterogenous Nuclear Riboprotein A3, FBRNP) pseudogene. Contains ESTs, STSs and GSSs /FEA=CDS_2 /DB_XREF=gi:3947836 /UG=Hs.247781 Human DNA sequence from clone 522P13 on chromosome 6p21.31-22.3. Contains a 60S Ribosomal Protein L21 pseudogene and an HNRNP A3 (Heterogenous Nuclear Riboprotein A3, FBRNP) pseudogene. Contains ESTs, STSs and GSSs AL024509 RP3-522P13.2 217323_at AF005487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005487.1 /DEF=Homo sapiens MHC class II antigen (DRB6) mRNA, HLA-DRB6*0201 allele, sequence. /FEA=mRNA /DB_XREF=gi:5915893 /UG=Hs.167385 Homo sapiens MHC class II antigen HLA-DRB6 mRNA, partial cds AF005487 major histocompatibility complex, class II, DR beta 6 (pseudogene) HLA-DRB6 3128 NR_001298 /// XR_426005 217324_at AL133099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133099.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B1521 (from clone DKFZp434B1521). /FEA=mRNA /DB_XREF=gi:6453555 /UG=Hs.272311 Homo sapiens mRNA; cDNA DKFZp434B1521 (from clone DKFZp434B1521) AL133099 217325_at X05421 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X05421 /DEF=Human DNA for 65kD keratin type II exons 6,7,8,9 and 3flank /FEA=CDS /DB_XREF=gi:34047 /UG=Hs.247767 Human DNA for 65kD keratin type II exons 6,7,8,9 and 3flank X05421 keratin 3 KRT3 3850 NM_057088 /// XM_005268859 /// XM_006719392 /// XM_006719393 0007010 // cytoskeleton organization // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype 0005882 // intermediate filament // non-traceable author statement /// 0045095 // keratin filament // traceable author statement 0005198 // structural molecule activity // inferred from mutant phenotype 217326_x_at AF009787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009787.1 /DEF=Homo sapiens T cell receptor beta chain (TCRB) mRNA, partial cds. /FEA=mRNA /GEN=TCRB /PROD=T cell receptor beta chain /DB_XREF=gi:2275604 /UG=Hs.166129 Homo sapiens T cell receptor beta chain (TCRB) mRNA, partial cds AF009787 SubName: Full=BV03S1J2.2 protein; Flags: Fragment; /// interleukin 23, alpha subunit p19 /// Homo sapiens mRNA for T cell receptor beta variable 28, partial cds, clone: non 374. /// Human TCR Cbeta1 chain cDNA. /// /// T cell receptor beta constant 2 /// T cell receptor beta joining 2-7 /// /// T cell receptor beta variable 19 BV03S1J2.2 /// IL23A /// TCRB /// TCRVB /// TRBC2 /// TRBC2 /// TRBJ2-7 /// TRBJ2-7 /// TRBV19 28568 /// 51561 NM_016584 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050776 // regulation of immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0045519 // interleukin-23 receptor binding // inferred from direct assay 217327_at AC005756 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC005756 /DEF=Homo sapiens chromosome 19, fosmid 39347 /FEA=CDS /DB_XREF=gi:3688091 /UG=Hs.247754 Homo sapiens chromosome 19, fosmid 39347 AC005756 /// transcription elongation factor B (SIII), polypeptide 1 pseudogene 28 AC104537.2 /// TCEB1P28 217328_at AF009787 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF009787.1 /DEF=Homo sapiens T cell receptor beta chain (TCRB) mRNA, partial cds. /FEA=mRNA /GEN=TCRB /PROD=T cell receptor beta chain /DB_XREF=gi:2275604 /UG=Hs.166129 Homo sapiens T cell receptor beta chain (TCRB) mRNA, partial cds AF009787 217329_x_at AF042164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF042164 /DEF=Homo sapiens cytochrome c oxidase subunit VIIb (COX7BP1) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3861485 /UG=Hs.247765 Homo sapiens cytochrome c oxidase subunit VIIb (COX7BP1) pseudogene, complete sequence AF042164 cytochrome c oxidase subunit VIIb pseudogene 1 /// COX7BP1 /// COX7BP1 217330_at AK025293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025293.1 /DEF=Homo sapiens cDNA: FLJ21640 fis, clone COL08304, highly similar to AF222980 Homo sapiens disrupted in Schizophrenia 1 protein (DISC1) mRNA. /FEA=mRNA /DB_XREF=gi:10437780 /UG=Hs.26985 disrupted in schizophrenia 1 AK025293 disrupted in schizophrenia 1 DISC1 27185 NM_001012957 /// NM_001012958 /// NM_001012959 /// NM_001039383 /// NM_001164537 /// NM_001164538 /// NM_001164539 /// NM_001164540 /// NM_001164541 /// NM_001164542 /// NM_001164544 /// NM_001164545 /// NM_001164546 /// NM_001164547 /// NM_001164548 /// NM_001164549 /// NM_001164550 /// NM_001164551 /// NM_001164552 /// NM_001164553 /// NM_001164554 /// NM_001164555 /// NM_001164556 /// NM_018662 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from mutant phenotype /// 0002052 // positive regulation of neuroblast proliferation // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from genetic interaction /// 0031929 // TOR signaling // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0090128 // regulation of synapse maturation // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // traceable author statement /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217331_at U63542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U63542.1 /DEF=Human putative FAP protein mRNA, partial cds. /FEA=mRNA /PROD=FAP protein /DB_XREF=gi:1890646 /UG=Hs.166101 Human putative FAP protein mRNA, partial cds U63542 0006508 // proteolysis // inferred from electronic annotation 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 217332_at AL133018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133018.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F0327 (from clone DKFZp434F0327). /FEA=mRNA /DB_XREF=gi:6453498 /UG=Hs.270527 Homo sapiens mRNA; cDNA DKFZp434F0327 (from clone DKFZp434F0327) AL133018 CTAGE family, member 11, pseudogene CTAGE11P 647288 NR_027466 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217333_at AL031903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031903 /DEF=Human DNA sequence from clone 1032F13 on chromosome Xq25-26.3. Contains a pseudogene similar to Keratin 18 (KRT18, Cytokeratin 18) and ESTs /FEA=CDS /DB_XREF=gi:3766260 /UG=Hs.247763 Human DNA sequence from clone 1032F13 on chromosome Xq25-26.3. Contains a pseudogene similar to Keratin 18 (KRT18, Cytokeratin 18) and ESTs AL031903 keratin 18 pseudogene 44 /// KRT18P44 /// KRT18P44 217334_at AL022727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022727 /DEF=Human DNA sequence from clone 80I19 on chromosome 6p21.31-22.2 Contains genes and pseudogenes for olfactory receptor-like proteins, STS, GSS /FEA=CDS_2 /DB_XREF=gi:3093312 /UG=Hs.247760 Human DNA sequence from clone 80I19 on chromosome 6p21.31-22.2 Contains genes and pseudogenes for olfactory receptor-like proteins, STS, GSS AL022727 olfactory receptor, family 2, subfamily J, member 3 OR2J3 442186 NM_001005216 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 217335_at AK023539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023539.1 /DEF=Homo sapiens cDNA FLJ13477 fis, clone PLACE1003638. /FEA=mRNA /DB_XREF=gi:10435501 /UG=Hs.272246 hypothetical protein FLJ11292 AK023539 uncharacterized protein FLJ11292 FLJ11292 55338 NM_018382 217336_at AL118510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL118510 /DEF=Human DNA sequence from clone RP5-858M22 on chromosome 20 Contains a pseudogene similar to 40S ribosomal protein S10, STSs and GSSs /FEA=CDS /DB_XREF=gi:6572394 /UG=Hs.272301 Human DNA sequence from clone RP5-858M22 on chromosome 20 Contains a pseudogene similar to 40S ribosomal protein S10, STSs and GSSs AL118510 ribosomal protein S10 pseudogene 2 /// RPS10P2 /// RPS10P2 217337_at AL021877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021877 /DEF=Human DNA sequence from clone RP1-101G11 on chromosome 22q12 Contains an ACO2 (Mitochondrial Aconitate Hydratase (Aconitase, Citrate Hydro-Lyase, EC 4.2.1.3)) pseudogene, ESTs, STSs, GSSs and a CpG islandn /FEA=CDS /DB_XREF=gi:3820976 /UG=Hs.247772 Human DNA sequence from clone RP1-101G11 on chromosome 22q12 Contains an ACO2 (Mitochondrial Aconitate Hydratase (Aconitase, Citrate Hydro-Lyase, EC 4.2.1.3)) pseudogene, ESTs, STSs, GSSs and a CpG islandn AL021877 RP1-101G11.2 217338_at AB041269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB041269.1 /DEF=Homo sapiens mRNA for keratin 19, partial cds, isolate:K19-141. /FEA=mRNA /GEN=keratin 19 /PROD=keratin 19 /DB_XREF=gi:7594735 /UG=Hs.272263 Homo sapiens mRNA for keratin 19, partial cds, isolate:K19-141 AB041269 keratin 19 pseudogene 2 KRT19P2 160313 NR_036685 0005882 // intermediate filament // inferred from electronic annotation 217339_x_at AJ275978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275978.1 /DEF=Homo sapiens partial mRNA LAGE-2b for hypothetical protein (LAGE-2 gene). /FEA=mRNA /GEN=LAGE-2 /PROD=hypothetical protein /DB_XREF=gi:7208842 /UG=Hs.167379 cancertestis antigen AJ275978 cancer/testis antigen 1A /// cancer/testis antigen 1B CTAG1A /// CTAG1B 1485 /// 246100 NM_001327 /// NM_139250 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217340_at AL024509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL024509 /DEF=Human DNA sequence from clone 522P13 on chromosome 6p21.31-22.3. Contains a 60S Ribosomal Protein L21 pseudogene and an HNRNP A3 (Heterogenous Nuclear Riboprotein A3, FBRNP) pseudogene. Contains ESTs, STSs and GSSs /FEA=CDS_1 /DB_XREF=gi:3947836 /UG=Hs.247780 Human DNA sequence from clone 522P13 on chromosome 6p21.31-22.3. Contains a 60S Ribosomal Protein L21 pseudogene and an HNRNP A3 (Heterogenous Nuclear Riboprotein A3, FBRNP) pseudogene. Contains ESTs, STSs and GSSs AL024509 RP3-522P13.1 217341_at L07810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L07810.1 /DEF=Human dynamin mRNA, alternative exon and 3 end of cds. /FEA=mRNA /PROD=dynamin /DB_XREF=gi:181854 /UG=Hs.166161 dynamin 1 L07810 217342_x_at AK023539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023539.1 /DEF=Homo sapiens cDNA FLJ13477 fis, clone PLACE1003638. /FEA=mRNA /DB_XREF=gi:10435501 /UG=Hs.272246 hypothetical protein FLJ11292 AK023539 uncharacterized protein FLJ11292 FLJ11292 55338 NM_018382 217343_at AL034369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034369 /DEF=Human DNA sequence from clone 149D17 on chromosome Xq22.2-23. Contains part of a PLRP2 (PNLIPRP2, Pancreatic Lipase Related Protein 2 Precursor, EC 3.1.1.3) LIKE gene and 5 exons of the COL4A5 and alternatively spliced COL4A6 genes for Collagen, ... /FEA=CDS_2 /DB_XREF=gi:3947691 /UG=Hs.247770 Human DNA sequence from clone 149D17 on chromosome Xq22.2-23. Contains part of a PLRP2 (PNLIPRP2, Pancreatic Lipase Related Protein 2 Precursor, EC 3.1.1.3) LIKE gene and 5 exons of the COL4A5 and alternatively spliced COL4A6 genes for Collagen, type IV, AL034369 RP6-149D17.1 217344_at AL022163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022163 /DEF=Human DNA sequence from clone 551E13 on chromosome Xp11.2-11.3 Contains farnesyl pyrophosphate synthetase pseudogene, VT4 protein pseudogene, EST, GSS /FEA=CDS /DB_XREF=gi:3947685 /UG=Hs.247769 Human DNA sequence from clone 551E13 on chromosome Xp11.2-11.3 Contains farnesyl pyrophosphate synthetase pseudogene, VT4 protein pseudogene, EST, GSS AL022163 farnesyl diphosphate synthase pseudogene 5 /// FDPSP5 /// FDPSP5 217345_at U91640 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U91640 /DEF=Human survival motor neuron pseudogene /FEA=CDS /DB_XREF=gi:2351795 /UG=Hs.166140 survival motor neuron pseudogene U91640 RP11-15P13.1 217346_at AL021395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021395 /DEF=Human DNA sequence from clone RP1-269M15 on chromosome 20q12-13.12 Contains a gene similar to peptidylprolyl isomerase (cyclophilin), part of the gene for receptor protein tyrosine phosphatase (RPTP-rho), ESTs, STSs, GSSs and CpG Islands /FEA=mRNA_1 /DB_XREF=gi:6249356 /UG=Hs.272279 Human DNA sequence from clone RP1-269M15 on chromosome 20q12-13.12 Contains a gene similar to peptidylprolyl isomerase (cyclophilin), part of the gene for receptor protein tyrosine phosphatase (RPTP-rho), ESTs, STSs, GSSs and CpG Islands AL021395 peptidylprolyl isomerase A (cyclophilin A) pseudogene 21 /// PPIAP21 /// PPIAP21 217347_at Z82202 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z82202 /DEF=Human DNA sequence from clone RP1-34P24 on chromosome 22 Contains a pseudogene similar to ribosomal protein L35, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:4107193 /UG=Hs.247778 Human DNA sequence from clone RP1-34P24 on chromosome 22 Contains a pseudogene similar to ribosomal protein L35, ESTs, STSs and GSSs Z82202 ribosomal protein L35 pseudogene 8 /// RPL35P8 /// RPL35P8 217348_x_at AK023853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023853.1 /DEF=Homo sapiens cDNA FLJ13791 fis, clone THYRO1000070. /FEA=mRNA /DB_XREF=gi:10435916 /UG=Hs.16714 Rho guanine exchange factor (GEF) 15 AK023853 Rho guanine nucleotide exchange factor (GEF) 15 ARHGEF15 22899 NM_025014 /// NM_173728 /// XM_005256537 /// XM_006721474 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 2000297 // negative regulation of synapse maturation // inferred from sequence or structural similarity 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217349_s_at U93305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U93305 /DEF=Homo sapiens A4 differentiation-dependent protein (A4), triple LIM domain protein (LMO6), and synaptophysin (SYP) genes, complete cds; and calcium channel alpha-1 subunit (CACNA1F) gene, partial cds /FEA=mRNA_1 /DB_XREF=gi:2707598 /UG=Hs.166173 LIM domain only 6 U93305 prickle homolog 3 (Drosophila) PRICKLE3 4007 NM_006150 /// XM_005272605 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217350_at AB041269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB041269.1 /DEF=Homo sapiens mRNA for keratin 19, partial cds, isolate:K19-141. /FEA=mRNA /GEN=keratin 19 /PROD=keratin 19 /DB_XREF=gi:7594735 /UG=Hs.272263 Homo sapiens mRNA for keratin 19, partial cds, isolate:K19-141 AB041269 keratin 19 pseudogene 2 /// microRNA 492 KRT19P2 /// MIR492 160313 /// 574449 NR_030171 /// NR_036685 0005882 // intermediate filament // inferred from electronic annotation 217351_at AL024458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL024458 /DEF=Human DNA sequence from clone 344I7 on chromosome Xp11.21-11.3. Contains a Keratin, Type II Cytoskeletal 8 (Cytokeratin 8, CYK8, KRT8) pseudogene, ESTs and a GSS /FEA=CDS /DB_XREF=gi:3980359 /UG=Hs.247777 Human DNA sequence from clone 344I7 on chromosome Xp11.21-11.3. Contains a Keratin, Type II Cytoskeletal 8 (Cytokeratin 8, CYK8, KRT8) pseudogene, ESTs and a GSS AL024458 keratin 8 pseudogene 17 /// KRT8P17 /// KRT8P17 217352_at AL050308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050308 /DEF=Human DNA sequence from clone GS1-164F24 on chromosome Xq26.3-27.3 Contains a NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:5262922 /UG=Hs.272277 Human DNA sequence from clone GS1-164F24 on chromosome Xq26.3-27.3 Contains a NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) pseudogene, ESTs, STSs and GSSs AL050308 GS1-164F24.1 217353_at AL022097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022097 /DEF=Homo sapiens DNA sequence from PAC 256G22 on chromosome 6p24.1-25.3. Contains a HNRNP Core Protein A1 LIKE pseudogene and an exon with similarity to yeast and fly phenylalanyl tRNA synthetase PHERS. Contains ESTs and GSSs /FEA=mRNA /DB_XREF=gi:3169107 /UG=Hs.166203 Homo sapiens DNA sequence from PAC 256G22 on chromosome 6p24.1-25.3. Contains a HNRNP Core Protein A1 LIKE pseudogene and an exon with similarity to yeast and fly phenylalanyl tRNA synthetase PHERS. Contains ESTs and GSSs AL022097 /// heterogeneous nuclear ribonucleoprotein A1 pseudogene 37 HNRNPA1P37 /// HNRNPA1P37 217354_s_at AL022313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022313 /DEF=Human DNA sequence from clone RP5-1119A7 on chromosome 22q12.2-12.3 Contains the TXN2 gene for mitochondrial thioredoxin, a novel gene, the EIF3S7 gene for eukaryotic translation initiation factor 3 subunit 7 (zeta, 6667kD) (EIF3-P66), the gene f... /FEA=CDS_3 /DB_XREF=gi:4200326 /UG=Hs.272270 Human DNA sequence from clone RP5-1119A7 on chromosome 22q12.2-12.3 Contains the TXN2 gene for mitochondrial thioredoxin, a novel gene, the EIF3S7 gene for eukaryotic translation initiation factor 3 subunit 7 (zeta, 6667kD) (EIF3-P66), the gene for a nov AL022313 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 217355_at AL022313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022313 /DEF=Human DNA sequence from clone RP5-1119A7 on chromosome 22q12.2-12.3 Contains the TXN2 gene for mitochondrial thioredoxin, a novel gene, the EIF3S7 gene for eukaryotic translation initiation factor 3 subunit 7 (zeta, 6667kD) (EIF3-P66), the gene f... /FEA=CDS_3 /DB_XREF=gi:4200326 /UG=Hs.272270 Human DNA sequence from clone RP5-1119A7 on chromosome 22q12.2-12.3 Contains the TXN2 gene for mitochondrial thioredoxin, a novel gene, the EIF3S7 gene for eukaryotic translation initiation factor 3 subunit 7 (zeta, 6667kD) (EIF3-P66), the gene for a nov AL022313 RP5-1119A7.11 217356_s_at S81916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S81916.1 /DEF=phosphoglycerate kinase {alternatively spliced} human, phosphoglycerate kinase deficient patient with episodes of muscl, mRNA Partial Mutant, 307 nt. /FEA=mRNA /PROD=phosphoglycerate kinase /DB_XREF=gi:1470308 /UG=Hs.169313 Phosphoglycerate kinase {alternatively spliced} human, phosphoglycerate kinase deficient patient with episodes of muscl, mRNA Partial Mutant, 307 nt S81916 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 217357_at AB028239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB028239 /DEF=Homo sapiens pseudogene for necdin /FEA=CDS /DB_XREF=gi:5672690 /UG=Hs.247843 Homo sapiens pseudogene for necdin AB028239 RP11-560G2.2 217358_at AL137715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137715.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K0423 (from clone DKFZp434K0423); partial cds. /FEA=mRNA /GEN=DKFZp434K0423 /PROD=hypothetical protein /DB_XREF=gi:6808130 /UG=Hs.272327 Homo sapiens mRNA; cDNA DKFZp434K0423 (from clone DKFZp434K0423); partial cds AL137715 DnaJ (Hsp40) homolog, subfamily C, member 16 DNAJC16 23341 NM_001287811 /// NM_015291 /// NR_109898 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217359_s_at M22094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M22094.1 /DEF=Human neural cell adhesion molecule (N-CAM) secreted isoform mRNA, 3 end. /FEA=mRNA /GEN=NCAM /DB_XREF=gi:189090 /UG=Hs.167988 neural cell adhesion molecule 1 M22094 neural cell adhesion molecule 1 NCAM1 4684 NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351 0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 217360_x_at AJ275408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275408 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo VI 162 /FEA=CDS /DB_XREF=gi:7573079 /UG=Hs.272363 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo VI 162 AJ275408 immunoglobulin heavy constant alpha 1 /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant mu /// immunoglobulin heavy variable 4-31 IGHA1 /// IGHG1 /// IGHG3 /// IGHM /// IGHV4-31 3493 /// 3500 /// 3502 /// 3507 /// 28396 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from direct assay /// 0032777 // Piccolo NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0003823 // antigen binding // traceable author statement /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217361_at X73110 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X73110 /DEF=H.sapiens RIalpha pseudogene /FEA=CDS /DB_XREF=gi:312817 /UG=Hs.247800 H.sapiens RIalpha pseudogene X73110 protein kinase, cAMP-dependent, regulatory, type I, alpha pseudogene /// PRKAR1AP /// PRKAR1AP 217362_x_at AF005487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF005487.1 /DEF=Homo sapiens MHC class II antigen (DRB6) mRNA, HLA-DRB6*0201 allele, sequence. /FEA=mRNA /DB_XREF=gi:5915893 /UG=Hs.167385 Homo sapiens MHC class II antigen HLA-DRB6 mRNA, partial cds AF005487 major histocompatibility complex, class II, DR beta 6 (pseudogene) HLA-DRB6 3128 NR_001298 /// XR_426005 217363_x_at AL031313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031313 /DEF=Human DNA sequence from clone 581F12 on chromosome Xq21. Contains Eukaryotic Translation Initiation Factor EIF3 P35 Subunit and 60S Ribosomal protein L22 pseudogenes. Contains ESTs /FEA=CDS_2 /DB_XREF=gi:4038573 /UG=Hs.247783 Human DNA sequence from clone 581F12 on chromosome Xq21. Contains Eukaryotic Translation Initiation Factor EIF3 P35 Subunit and 60S Ribosomal protein L22 pseudogenes. Contains ESTs AL031313 ribosomal protein L22 pseudogene 22 /// RPL22P22 /// RPL22P22 217364_x_at AL031313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031313 /DEF=Human DNA sequence from clone 581F12 on chromosome Xq21. Contains Eukaryotic Translation Initiation Factor EIF3 P35 Subunit and 60S Ribosomal protein L22 pseudogenes. Contains ESTs /FEA=CDS_1 /DB_XREF=gi:4038573 /UG=Hs.247782 Human DNA sequence from clone 581F12 on chromosome Xq21. Contains Eukaryotic Translation Initiation Factor EIF3 P35 Subunit and 60S Ribosomal protein L22 pseudogenes. Contains ESTs AL031313 RP4-581F12.1 217365_at AL022101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL022101 /DEF=Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contain... /FEA=CDS_3 /DB_XREF=gi:3171895 /UG=Hs.247785 Homo sapiens DNA sequence from PAC 845O24 on chromosome 1p36.1-36.2. Contains a gene for a Heterogenous Nuclear Ribonucleoprotein HNRNP C1 LIKE protein and four genes similar to Melanoma Preferentially Expressed Antigen PRAME and KIAA0014. Contains ESTs, AL022101 PRAME family member 11 PRAMEF11 440560 NM_001146344 /// XM_006710645 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation 0042974 // retinoic acid receptor binding // inferred from electronic annotation 217366_at Z37994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z37994 /DEF=H.sapiens alpha E-catenin pseudogene /FEA=CDS /DB_XREF=gi:556810 /UG=Hs.247788 catenin (cadherin-associated protein), alpha pseudogene 1 Z37994 CTNNAP1 217367_s_at AB007855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB007855.1 /DEF=Homo sapiens KIAA0395 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0395 /DB_XREF=gi:2662070 /UG=Hs.167839 KIAA0395 protein AB007855 zinc fingers and homeoboxes 3 ZHX3 23051 NM_015035 /// XM_005260341 /// XM_005260343 /// XM_006723747 /// XM_006723748 /// XM_006723749 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 217368_at X69909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X69909 /DEF=H.sapiens pseudogene for mitochondrial ATP synthase c subunit (P2 form) /FEA=CDS /DB_XREF=gi:28936 /UG=Hs.247790 H.sapiens pseudogene for mitochondrial ATP synthase c subunit (P2 form) X69909 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) pseudogene 1 /// ATP5G2P1 /// ATP5G2P1 217369_at AJ275383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275383 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo IV 72 /FEA=CDS /DB_XREF=gi:7573027 /UG=Hs.272358 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo IV 72 AJ275383 immunoglobulin heavy constant gamma 1 (G1m marker) /// uncharacterized LOC101930405 IGHG1 /// LOC101930405 3500 /// 101930405 XM_005275748 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 217370_x_at S75762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S75762.1 /DEF=FUS...CHOP human, myxoid liposarcoma specimens, mRNA Partial Mutant, 3 genes, 652 nt. /FEA=mRNA /GEN=FUS-CHOP /PROD=FUS-CHOP fusion protein /DB_XREF=gi:861473 /UG=Hs.99969 fusion, derived from t(12;16) malignant liposarcoma S75762 FUS RNA binding protein FUS 2521 NM_001010850 /// NM_001170634 /// NM_001170937 /// NM_004960 /// NR_028388 /// XM_005255233 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001955 // blood vessel maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006983 // ER overload response // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044324 // regulation of transcription involved in anterior/posterior axis specification // inferred from electronic annotation /// 0044324 // regulation of transcription involved in anterior/posterior axis specification // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000016 // negative regulation of determination of dorsal identity // inferred from direct assay /// 2000016 // negative regulation of determination of dorsal identity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217371_s_at Y09908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09908.1 /DEF=H.sapiens mRNA for interleukin-15. /FEA=mRNA /GEN=IL-15 /PROD=interleukin-15 /DB_XREF=gi:2143255 /UG=Hs.168132 interleukin 15 Y09908 interleukin 15 IL15 3600 NM_000585 /// NM_172174 /// NM_172175 /// NR_037840 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001866 // NK T cell proliferation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0045062 // extrathymic T cell selection // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050691 // regulation of defense response to virus by host // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217372_at Y09908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y09908.1 /DEF=H.sapiens mRNA for interleukin-15. /FEA=mRNA /GEN=IL-15 /PROD=interleukin-15 /DB_XREF=gi:2143255 /UG=Hs.168132 interleukin 15 Y09908 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001866 // NK T cell proliferation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032819 // positive regulation of natural killer cell proliferation // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from electronic annotation /// 0045062 // extrathymic T cell selection // inferred from electronic annotation /// 0045580 // regulation of T cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050691 // regulation of defense response to virus by host // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217373_x_at AJ276888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ276888.1 /DEF=Homo sapiens non-productive mRNA for p53-binding protein, alternatively spliced variant DS2 (MDM2 gene). /FEA=CDS /GEN=MDM2 /PROD=p53-binding protein /DB_XREF=gi:7327962 /UG=Hs.272346 Homo sapiens non-productive mRNA for p53-binding protein, alternatively spliced variant DS2 (MDM2 gene) AJ276888 MDM2 proto-oncogene, E3 ubiquitin protein ligase MDM2 4193 NM_001145336 /// NM_001145337 /// NM_001145339 /// NM_001145340 /// NM_001278462 /// NM_002392 /// NM_006878 /// NM_006879 /// NM_006880 /// NM_006881 /// NM_006882 /// NM_032739 /// XM_005268872 /// XM_006719399 /// XM_006719400 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018205 // peptidyl-lysine modification // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071301 // cellular response to vitamin B1 // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071494 // cellular response to UV-C // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 217374_x_at AC006033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC006033 /DEF=Homo sapiens BAC clone RP11-121A8 from 7p14-p13 /FEA=CDS_2 /DB_XREF=gi:4309948 /UG=Hs.247840 Homo sapiens BAC clone RP11-121A8 from 7p14-p13 AC006033 217375_at Z93929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z93929 /DEF=Human DNA sequence from clone 272E8 on chromosome Xp22.13-22.31. Contains a pseudogene similar to MDM2-Like P53-binding protein gene. Contains STSs, GSSs and a CA repeat polymorphism /FEA=CDS /DB_XREF=gi:3425887 /UG=Hs.247809 Human DNA sequence from clone 272E8 on chromosome Xp22.13-22.31. Contains a pseudogene similar to MDM2-Like P53-binding protein gene. Contains STSs, GSSs and a CA repeat polymorphism Z93929 RP1-272E8.1 217376_at AL109809 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109809 /DEF=Human DNA sequence from clone RP4-673D20 on chromosome 20. Contains a PTPNS (protein tyrosine phosphatase, non-receptor type substrate) family pseudogene, STSs, GSSs and a CpG island /FEA=CDS /DB_XREF=gi:6634478 /UG=Hs.272342 Human DNA sequence from clone RP4-673D20 on chromosome 20. Contains a PTPNS (protein tyrosine phosphatase, non-receptor type substrate) family pseudogene, STSs, GSSs and a CpG island AL109809 cytoskeleton associated protein 2-like pseudogene LOC100289473 100289473 NR_037142 217377_x_at AF041811 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF041811.2 /DEF=Homo sapiens ETS related protein-growth factor receptor tyrosine kinase fusion proteins (ETV6-NTRK3 fusion) mRNA, partial cds. /FEA=mRNA /GEN=ETV6-NTRK3 fusion /PROD=ETS related protein-growth factor receptortyrosine kinase fusion proteins /DB_XREF=gi:6274523 /UG=Hs.169081 ets variant gene 6 (TEL oncogene) AF041811 neurotrophic tyrosine kinase, receptor, type 3 NTRK3 4916 NM_001007156 /// NM_001012338 /// NM_001243101 /// NM_002530 /// XM_006720542 /// XM_006720543 /// XM_006720544 /// XM_006720545 /// XM_006720546 /// XM_006720547 /// XM_006720548 /// XM_006720549 /// XM_006720550 /// XM_006720551 /// XM_006720552 0000187 // activation of MAPK activity // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019056 // modulation by virus of host transcription // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032856 // activation of Ras GTPase activity // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from direct assay /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048665 // neuron fate specification // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048691 // positive regulation of axon extension involved in regeneration // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043121 // neurotrophin binding // traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation 217378_x_at X51887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X51887 /DEF=Human V108 gene encoding an immunoglobulin kappa orphon /FEA=CDS /DB_XREF=gi:37616 /UG=Hs.247804 immunoglobulin kappa variable 1OR2-108 X51887 immunoglobulin kappa variable 1/OR2-108 (non-functional) /// IGKV1OR2-108 /// IGKV1OR2-108 0005515 // protein binding // inferred from electronic annotation 217379_at AL121934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121934 /DEF=Human DNA sequence from clone RP11-209A2 on chromosome 6. Contains an RPL10 (60S ribosomal protein L10) pseudogene, ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:9795199 /UG=Hs.272340 Human DNA sequence from clone RP11-209A2 on chromosome 6. Contains an RPL10 (60S ribosomal protein L10) pseudogene, ESTs, STSs and GSSs AL121934 RP11-209A2.1 217380_s_at U92992 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U92992.1 /DEF=Homo sapiens clone DT1P1A11 mRNA, CAG repeat region. /FEA=mRNA /DB_XREF=gi:2781410 /UG=Hs.168303 Homo sapiens clone DT1P1A11 mRNA, CAG repeat region U92992 ADD3 antisense RNA 1 ADD3-AS1 100505933 NR_038943 217381_s_at X69383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X69383 /DEF=H.sapiens gene for T cell receptor gamma V region 5 /FEA=CDS_2 /DB_XREF=gi:37009 /UG=Hs.247801 H.sapiens gene for T cell receptor gamma V region 5 X69383 TCR gamma alternate reading frame protein TARP 445347 NM_001003799 /// NM_001003806 /// XM_006715732 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement 217382_at U85978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U85978 /DEF=Human chloride channel protein (p64) pseudogene, partial cds /FEA=CDS /DB_XREF=gi:4099324 /UG=Hs.247834 Human chloride channel protein (p64) pseudogene, partial cds U85978 chloride intracellular channel 1 pseudogene 1 /// CLIC1P1 /// CLIC1P1 217383_at S81916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S81916.1 /DEF=phosphoglycerate kinase {alternatively spliced} human, phosphoglycerate kinase deficient patient with episodes of muscl, mRNA Partial Mutant, 307 nt. /FEA=mRNA /PROD=phosphoglycerate kinase /DB_XREF=gi:1470308 /UG=Hs.169313 Phosphoglycerate kinase {alternatively spliced} human, phosphoglycerate kinase deficient patient with episodes of muscl, mRNA Partial Mutant, 307 nt S81916 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 217384_x_at AJ275374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275374 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, clone 19 /FEA=CDS /DB_XREF=gi:7573008 /UG=Hs.272357 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, clone 19 AJ275374 uncharacterized LOC100293211 LOC100293211 100293211 XM_006710246 0005515 // protein binding // inferred from electronic annotation 217385_at AL023773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL023773 /DEF=Human DNA sequence from clone 406C18 on chromosome Xq27.1-27.3. Contains two MAGE (Melanoma Associated Antigen) family pseudogenes, GSSs and an STS /FEA=CDS /DB_XREF=gi:3449129 /UG=Hs.247810 Human DNA sequence from clone 406C18 on chromosome Xq27.1-27.3. Contains two MAGE (Melanoma Associated Antigen) family pseudogenes, GSSs and an STS AL023773 RP3-406C18.2 217386_at AL109953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109953 /DEF=Human DNA sequence from clone RP4-746H2 on chromosome 20. Contains a pseudogene similar to prokaryotic RPS11 (30S ribosomal protein S11), ESTs, STSs and GSSs /FEA=CDS /DB_XREF=gi:7019754 /UG=Hs.272351 Human DNA sequence from clone RP4-746H2 on chromosome 20. Contains a pseudogene similar to prokaryotic RPS11 (30S ribosomal protein S11), ESTs, STSs and GSSs AL109953 mitochondrial ribosomal protein S11 pseudogene 1 /// MRPS11P1 /// MRPS11P1 217387_at AJ000388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ000388.1 /DEF=Homo sapiens mRNA for calpain-like protease CANPX. /FEA=mRNA /PROD=calpain-like protease, CANPX /DB_XREF=gi:2274961 /UG=Hs.169172 calpain 6 AJ000388 calpain 6 CAPN6 827 NM_014289 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0006508 // proteolysis // not recorded /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0008017 // microtubule binding // inferred from sequence or structural similarity 217388_s_at D55639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D55639.1 /DEF=Human monocyte PABL (pseudoautosomal boundary-like sequence) mRNA, clone Mo1. /FEA=mRNA /DB_XREF=gi:1255614 /UG=Hs.169139 kynureninase (L-kynurenine hydrolase) D55639 kynureninase KYNU 8942 NM_001032998 /// NM_001199241 /// NM_003937 0006569 // tryptophan catabolic process // inferred from mutant phenotype /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034516 // response to vitamin B6 // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030429 // kynureninase activity // inferred from direct assay /// 0030429 // kynureninase activity // inferred from mutant phenotype /// 0030429 // kynureninase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 217389_s_at AF101388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF101388.1 /DEF=Homo sapiens activating transcription factor 5 (ATF5) mRNA, partial cds. /FEA=mRNA /GEN=ATF5 /PROD=activating transcription factor 5 /DB_XREF=gi:4731160 /UG=Hs.9754 activating transcription factor 5 AF101388 activating transcription factor 5 ATF5 22809 NM_001193646 /// NM_001290746 /// NM_012068 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021889 // olfactory bulb interneuron differentiation // inferred from electronic annotation /// 0021891 // olfactory bulb interneuron development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217390_x_at AJ275371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ275371 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, clone 16 /FEA=CDS /DB_XREF=gi:7573002 /UG=Hs.272356 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, clone 16 AJ275371 217391_x_at X72882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X72882 /DEF=H.sapiens 14A6CK DNA sequence /FEA=CDS /DB_XREF=gi:667005 /UG=Hs.169275 H.sapiens 14A6CK DNA sequence X72882 217392_at AL024493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL024493 /DEF=Human DNA sequence from clone 452M16 on chromosome Xq21.1-21.33 Contains capping protein alpha subunit isoform 1 pseudogene, STS, GSS, and CA repeat /FEA=CDS /DB_XREF=gi:3288439 /UG=Hs.247811 Human DNA sequence from clone 452M16 on chromosome Xq21.1-21.33 Contains capping protein alpha subunit isoform 1 pseudogene, STS, GSS, and CA repeat AL024493 RP3-452M16.1 217393_x_at AL109622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109622 /DEF=Human DNA sequence from clone RP3-526F5 on chromosome Xq26.3-28. Contains the gene for a novel protein similar to UBE2N (ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)), ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:6002166 /UG=Hs.272352 Human DNA sequence from clone RP3-526F5 on chromosome Xq26.3-28. Contains the gene for a novel protein similar to UBE2N (ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)), ESTs, STSs and GSSs AL109622 ubiquitin-conjugating enzyme E2N-like UBE2NL 389898 NM_001012989 /// NR_121210 0008152 // metabolic process // inferred from electronic annotation 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217394_at AE000659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AE000659 /DEF=Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence /FEA=CDS_9 /DB_XREF=gi:2358025 /UG=Hs.272547 Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence AE000659 Homo sapiens mRNA for T cell receptor alpha variable 13, partial cds, clone: SEB 85. /// T cell receptor alpha variable 13-1 /// TCR-alpha /// TRAV13-1 /// TRAV13-1 0005515 // protein binding // inferred from electronic annotation 217395_at X55503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X55503 /DEF=H.sapiens pseudogene for metallothionein and AGCT repetitive element /FEA=mRNA /DB_XREF=gi:38328 /UG=Hs.194762 Human metallothionein IV (MTIV) gene, complete cds X55503 metallothionein 4 MT4 84560 NM_032935 0006875 // cellular metal ion homeostasis // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement 0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217396_at AL133075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133075.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M0317 (from clone DKFZp434M0317). /FEA=mRNA /DB_XREF=gi:6453518 /UG=Hs.274560 Homo sapiens mRNA; cDNA DKFZp434M0317 (from clone DKFZp434M0317) AL133075 217397_at AE000659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AE000659 /DEF=Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence /FEA=CDS_1 /DB_XREF=gi:2358025 /UG=Hs.272469 Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence AE000659 Homo sapiens mRNA for T cell receptor alpha variable 10, partial cds, clone: un 14. /// SubName: Full=Alpha-chain C region; Flags: Fragment; /// T cell receptor alpha variable 10 /// /// YME1-like 1 ATPase TCRA /// TCRA /// TRAV10 /// TRAV10 /// YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217398_x_at AK026525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026525.1 /DEF=Homo sapiens cDNA: FLJ22872 fis, clone KAT02551, highly similar to HUMGAPDH Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA. /FEA=mRNA /DB_XREF=gi:10439402 /UG=Hs.169476 glyceraldehyde-3-phosphate dehydrogenase AK026525 glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 217399_s_at AF032887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF032887 /DEF=Homo sapiens forkhead (FKHRL1P1) pseudogene, chromosome 17 /FEA=CDS /DB_XREF=gi:2895505 /UG=Hs.274468 forkhead box O3B AF032887 forkhead box O3 /// forkhead box O3B pseudogene FOXO3 /// FOXO3B 2309 /// 2310 NM_001455 /// NM_201559 /// NR_026718 /// XM_005266867 /// XM_005266868 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay 217400_at AL034410 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034410 /DEF=Human DNA sequence from clone 774G10 on chromosome Xp11.23-11.3 Contains a pseudogene similar to cyclin protein, ESTs, STS and GSSs /FEA=CDS /DB_XREF=gi:4678510 /UG=Hs.247846 Human DNA sequence from clone 774G10 on chromosome Xp11.23-11.3 Contains a pseudogene similar to cyclin protein, ESTs, STS and GSSs AL034410 proliferating cell nuclear antigen pseudogene 3 /// PCNAP3 /// PCNAP3 217401_at AL035555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035555 /DEF=Human DNA sequence from clone 217P22 on chromosome 6p21.1-21.31. Contains part of a novel Dynein heavy chain family protein gene and a pseudogene similar to mouse MIDA1. Contains an EST, an STS and GSSs /FEA=CDS /DB_XREF=gi:4581305 /UG=Hs.247849 Human DNA sequence from clone 217P22 on chromosome 6p21.1-21.31. Contains part of a novel Dynein heavy chain family protein gene and a pseudogene similar to mouse MIDA1. Contains an EST, an STS and GSSs AL035555 RP1-217P22.2 217402_at AL031732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031732 /DEF=Human DNA sequence from clone 410I8 on chromosome 1p35.1-36.23 Contains ESTs, CA repeat (D1S507), pseudogene similar to cofactor A. and GSSs /FEA=CDS /DB_XREF=gi:4581343 /UG=Hs.247847 Human DNA sequence from clone 410I8 on chromosome 1p35.1-36.23 Contains ESTs, CA repeat (D1S507), pseudogene similar to cofactor A. and GSSs AL031732 /// tubulin folding cofactor A pseudogene 2 TBCAP2 /// TBCAP2 217403_s_at AC074331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC074331 /DEF=Homo sapiens chromosome 19, BAC CIT-HSPC_204F22 (BC228680), complete sequence; contains bacterial insertion element /FEA=CDS_4 /DB_XREF=gi:9502399 /UG=Hs.9615 myosin regulatory light chain 2, smooth muscle isoform AC074331 zinc finger protein 227 ZNF227 7770 NM_001289166 /// NM_001289167 /// NM_001289168 /// NM_001289169 /// NM_001289170 /// NM_001289171 /// NM_001289172 /// NM_001289173 /// NM_182490 /// XM_005259232 /// XM_006723370 /// XM_006723371 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 217404_s_at X16468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X16468.1 /DEF=Human mRNA for alpha-1 type II collagen. /FEA=CDS /DB_XREF=gi:29515 /UG=Hs.81343 collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) X16468 collagen, type II, alpha 1 COL2A1 1280 NM_001844 /// NM_033150 /// XM_006719242 0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0030903 // notochord development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051216 // cartilage development // traceable author statement /// 0060021 // palate development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060272 // embryonic skeletal joint morphogenesis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005585 // collagen type II trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030020 // extracellular matrix structural constituent conferring tensile strength // inferred by curator /// 0042802 // identical protein binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 217405_x_at AL031230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL031230 /DEF=Human DNA sequence from clone 73M23 on chromosome 6p22.2-22.3. Contains the 5 part of the possibly alternatively spliced gene for Phosphatidylinositol-glycan-specific Phospholipase D 1 precursor (EC 3.1.4.50, PIGPLD1, Glycoprotein Phospholipase D... /FEA=CDS_2 /DB_XREF=gi:3947845 /UG=Hs.272529 glycosylphosphatidylinositol specific phospholipase D1 AL031230 glycosylphosphatidylinositol specific phospholipase D1 GPLD1 2822 NM_001503 /// NM_177483 /// XM_005249018 0001503 // ossification // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from sequence or structural similarity /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006507 // GPI anchor release // inferred from direct assay /// 0006507 // GPI anchor release // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from sequence or structural similarity /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010897 // negative regulation of triglyceride catabolic process // inferred from sequence or structural similarity /// 0010907 // positive regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035701 // hematopoietic stem cell migration // traceable author statement /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0046470 // phosphatidylcholine metabolic process // inferred from sequence or structural similarity /// 0046470 // phosphatidylcholine metabolic process // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071401 // cellular response to triglyceride // inferred from mutant phenotype /// 0071467 // cellular response to pH // inferred from direct assay /// 0097241 // hematopoietic stem cell migration to bone marrow // traceable author statement /// 1900076 // regulation of cellular response to insulin stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004621 // glycosylphosphatidylinositol phospholipase D activity // inferred from direct assay /// 0004621 // glycosylphosphatidylinositol phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from sequence or structural similarity 217406_at AL021937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL021937 /DEF=Human DNA sequence from clone RP1-149A16 on chromosome 22 Contains an IGLC (Immunoglobulin Lambda Chain C) pseudogene, the RFPL3 gene for Ret finger protein-like 3, the RFPL3S gene for Ret finger protein-like 3 antisense, the gene for a novel Immu... /FEA=mRNA_2 /DB_XREF=gi:4165210 /UG=Hs.272521 Human DNA sequence from clone RP1-149A16 on chromosome 22 Contains an IGLC (Immunoglobulin Lambda Chain C) pseudogene, the RFPL3 gene for Ret finger protein-like 3, the RFPL3S gene for Ret finger protein-like 3 antisense, the gene for a novel Immunoglobul AL021937 RP1-149A16.17 217407_x_at U37220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U37220.1 /DEF=Human cyclophilin-like protein mRNA, partial cds. /FEA=mRNA /PROD=cyclophilin-like protein /DB_XREF=gi:1199599 /UG=Hs.93523 peptidylprolyl isomerase (cyclophilin)-like 2 U37220 peptidylprolyl isomerase (cyclophilin)-like 2 PPIL2 23759 NM_014337 /// NM_148175 /// NM_148176 /// XM_005261447 /// XM_005261448 /// XM_006724197 /// XM_006724198 0000209 // protein polyubiquitination // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 217408_at AL050361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050361.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564H0223 (from clone DKFZp564H0223). /FEA=mRNA /DB_XREF=gi:4914594 /UG=Hs.274417 PTD017 protein AL050361 mitochondrial ribosomal protein S18B MRPS18B 28973 NM_014046 /// XM_005249030 /// XM_005272798 /// XM_005274944 /// XM_005275098 /// XM_005275236 /// XM_005275374 /// XM_005275534 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 217409_at Z22957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22957.1 /DEF=H.sapiens myosin I homologue. /FEA=mRNA /PROD=myosin I homologue /DB_XREF=gi:312049 /UG=Hs.170157 myosin VA (heavy polypeptide 12, myoxin) Z22957 217410_at AK021586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021586.1 /DEF=Homo sapiens cDNA FLJ11524 fis, clone HEMBA1002547, highly similar to Homo sapiens agrin precursor mRNA. /FEA=mRNA /DB_XREF=gi:10432794 /UG=Hs.273330 Homo sapiens, clone IMAGE:3506210, mRNA, partial cds AK021586 agrin AGRN 375790 NM_198576 /// XM_005244749 /// XM_006710633 /// XM_006710634 /// XM_006710635 /// XM_006710636 /// XM_006710637 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from direct assay /// 0043113 // receptor clustering // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045162 // clustering of voltage-gated sodium channels // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045887 // positive regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050808 // synapse organization // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from sequence or structural similarity /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0030548 // acetylcholine receptor regulator activity // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // traceable author statement /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity 217411_s_at AF072826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF072826.1 /DEF=Homo sapiens Raf responsive zinc finger protein isoform (RREB1), partial cds. /FEA=mRNA /GEN=RREB1 /PROD=Raf responsive zinc finger protein isoform /DB_XREF=gi:3309594 /UG=Hs.171942 ras responsive element binding protein 1 AF072826 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217412_at AE000659 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AE000659 /DEF=Homo sapiens T-cell receptor alpha delta locus from bases 250472 to 501670 (section 2 of 5) of the Complete Nucleotide Sequence /FEA=CDS_12 /DB_XREF=gi:2358025 /UG=Hs.272549 Homo sapiens T cell receptor alpha chain (TCRA) mRNA, partial cds AE000659 SubName: Full=V-alpha 22; Flags: Precursor; Fragment; /// T cell receptor alpha variable 9-2 /// T-Cell Receptor V-alpha region /// TRAV9-2 /// TRAV9-2 0005515 // protein binding // inferred from electronic annotation 217413_s_at X71923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X71923.1 /DEF=H.sapiens XB gene for tenascin-X, exons 1 & 2. /FEA=mRNA /GEN=XB /PROD=tenascin-X precursor /DB_XREF=gi:394779 /UG=Hs.169886 tenascin XB X71923 tenascin XB TNXB 7148 NM_019105 /// NM_032470 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043506 // regulation of JUN kinase activity // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from sequence or structural similarity /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 217414_x_at V00489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:V00489 /DEF=Human alpha-globin gene with flanks /FEA=mRNA /DB_XREF=gi:28548 /UG=Hs.272572 hemoglobin, alpha 2 V00489 hemoglobin, alpha 1 /// hemoglobin, alpha 2 HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217415_at M21610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M21610.1 /DEF=Human RNA polymerase II mRNA, 3 end of exon 5. /FEA=mRNA /GEN=POLR2 /DB_XREF=gi:190159 /UG=Hs.171880 polymerase (RNA) II (DNA directed) polypeptide A (220kD) M21610 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa POLR2A 5430 NM_000937 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001172 // transcription, RNA-templated // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0003968 // RNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217416_x_at AK000918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000918.1 /DEF=Homo sapiens cDNA FLJ10056 fis, clone HEMBA1001351, highly similar to Homo sapiens VAMP-associated protein of 33 kDa mRNA. /FEA=mRNA /DB_XREF=gi:7021883 /UG=Hs.9006 VAMP (vesicle-associated membrane protein)-associated protein A (33kD) AK000918 217417_at Z22957 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z22957.1 /DEF=H.sapiens myosin I homologue. /FEA=mRNA /PROD=myosin I homologue /DB_XREF=gi:312049 /UG=Hs.170157 myosin VA (heavy polypeptide 12, myoxin) Z22957 myosin VA (heavy chain 12, myoxin) MYO5A 4644 NM_000259 /// NM_001142495 /// XM_005254397 /// XM_005254398 /// XM_005254399 /// XM_005254400 /// XM_005254401 /// XM_005254402 /// XM_005254403 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006887 // exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031585 // regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0031987 // locomotion involved in locomotory behavior // inferred from electronic annotation /// 0032252 // secretory granule localization // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042759 // long-chain fatty acid biosynthetic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051643 // endoplasmic reticulum localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030426 // growth cone // non-traceable author statement /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0000146 // microfilament motor activity // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation 217418_x_at X12530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X12530.1 /DEF=Human mRNA for B lymphocyte antigen CD20 (B1, Bp35). /FEA=mRNA /DB_XREF=gi:29773 /UG=Hs.89751 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) X12530 membrane-spanning 4-domains, subfamily A, member 1 MS4A1 931 NM_021950 /// NM_152866 0006955 // immune response // traceable author statement /// 0006959 // humoral immune response // non-traceable author statement /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay 217419_x_at AK021586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021586.1 /DEF=Homo sapiens cDNA FLJ11524 fis, clone HEMBA1002547, highly similar to Homo sapiens agrin precursor mRNA. /FEA=mRNA /DB_XREF=gi:10432794 /UG=Hs.273330 Homo sapiens, clone IMAGE:3506210, mRNA, partial cds AK021586 agrin AGRN 375790 NM_198576 /// XM_005244749 /// XM_006710633 /// XM_006710634 /// XM_006710635 /// XM_006710636 /// XM_006710637 0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008582 // regulation of synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from direct assay /// 0043113 // receptor clustering // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045162 // clustering of voltage-gated sodium channels // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045887 // positive regulation of synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050808 // synapse organization // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from sequence or structural similarity /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0030548 // acetylcholine receptor regulator activity // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // traceable author statement /// 0043395 // heparan sulfate proteoglycan binding // inferred from sequence or structural similarity 217420_s_at M21610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M21610.1 /DEF=Human RNA polymerase II mRNA, 3 end of exon 5. /FEA=mRNA /GEN=POLR2 /DB_XREF=gi:190159 /UG=Hs.171880 polymerase (RNA) II (DNA directed) polypeptide A (220kD) M21610 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa POLR2A 5430 NM_000937 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001172 // transcription, RNA-templated // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0003968 // RNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217421_at AK000397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000397.1 /DEF=Homo sapiens cDNA FLJ20390 fis, clone KAIA4599. /FEA=mRNA /DB_XREF=gi:7020458 /UG=Hs.274150 hypothetical protein FLJ10351 AK000397 piwi-like RNA-mediated gene silencing 2 PIWIL2 55124 NM_001135721 /// NM_018068 /// XM_005273550 /// XM_005273551 0000966 // RNA 5'-end processing // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005844 // polysome // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0043186 // P granule // inferred from sequence or structural similarity /// 0071546 // pi-body // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0034584 // piRNA binding // inferred from direct assay /// 0034584 // piRNA binding // inferred from sequence or structural similarity 217422_s_at X52785 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X52785.1 /DEF=H.sapiens CD22 mRNA. /FEA=mRNA /PROD=CD22 antigen /DB_XREF=gi:29778 /UG=Hs.171763 CD22 antigen X52785 CD22 molecule CD22 933 NM_001185099 /// NM_001185100 /// NM_001185101 /// NM_001278417 /// NM_001771 /// NM_024916 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217423_at AK000257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000257.1 /DEF=Homo sapiens cDNA FLJ20250 fis, clone COLF6635. /FEA=mRNA /DB_XREF=gi:7020217 /UG=Hs.274505 Homo sapiens mRNA; cDNA DKFZp564A216 (from clone DKFZp564A216) AK000257 217424_at AL122122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122122.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L098 (from clone DKFZp434L098). /FEA=mRNA /DB_XREF=gi:6102949 /UG=Hs.274559 Homo sapiens mRNA; cDNA DKFZp434L098 (from clone DKFZp434L098) AL122122 217425_at Y10259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y10259.1 /DEF=H.sapiens ACTH receptor mRNA 3UTR. /FEA=mRNA /DB_XREF=gi:2230860 /UG=Hs.274501 H.sapiens ACTH receptor mRNA 3UTR Y10259 melanocortin 2 receptor (adrenocorticotropic hormone) MC2R 4158 NM_000529 /// NM_001291911 0001890 // placenta development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004978 // corticotropin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217426_at L11372 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L11372.1 /DEF=Human protocadherin 43 mRNA, 3 end of cds for alternative splicing PC43-12. /FEA=mRNA /PROD=protocadherin 43 /DB_XREF=gi:307327 /UG=Hs.173310 protocadherin gamma subfamily C, 3 L11372 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 217427_s_at X75296 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X75296.1 /DEF=H.sapiens TUP1-like enhancer of split gene 1 (TUPLE1) mRNA. /FEA=mRNA /GEN=TUPLE1 /PROD=TUP1 like enhancer of SPLIT gene 1 /DB_XREF=gi:434982 /UG=Hs.172350 HIR (histone cell cycle regulation defective, S. cerevisiae) homolog A X75296 histone cell cycle regulator HIRA 7290 NM_003325 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217428_s_at X98568 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X98568 /DEF=H.sapiens type X collagen gene /FEA=mRNA /DB_XREF=gi:1405722 /UG=Hs.179729 collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia) X98568 collagen, type X, alpha 1 COL10A1 1300 NM_000493 /// XM_006715332 /// XM_006715333 0001501 // skeletal system development // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217429_at AL049307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049307.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A216 (from clone DKFZp564A216). /FEA=mRNA /DB_XREF=gi:4500076 /UG=Hs.274505 Homo sapiens mRNA; cDNA DKFZp564A216 (from clone DKFZp564A216) AL049307 217430_x_at Y15916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15916.1 /DEF=Homo sapiens mRNA for chimaeric transcript of collagen type 1 alpha 1 and platelet derived growth factor beta, 189 bp. /FEA=mRNA /PROD=COL1A1 and PDGFB fusion transcript /DB_XREF=gi:3288488 /UG=Hs.172928 collagen, type I, alpha 1 Y15916 collagen, type I, alpha 1 COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 217431_x_at S67289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S67289.1 /DEF=CYBB=cytochrome b558 gp91-phox subunit human, mRNA Partial Mutant, 102 nt. /FEA=CDS /GEN=CYBB /PROD=cytochrome b558 gp91-phox subunit /DB_XREF=gi:459299 /UG=Hs.88974 cytochrome b-245, beta polypeptide (chronic granulomatous disease) S67289 cytochrome b-245, beta polypeptide CYBB 1536 NM_000397 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from mutant phenotype 217432_s_at AF179281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF179281.1 /DEF=Homo sapiens normal control W-IDS fusion transcript, mRNA sequence. /FEA=mRNA /DB_XREF=gi:7542379 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) AF179281 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217433_at AB029026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029026.1 /DEF=Homo sapiens mRNA for KIAA1103 protein, partial cds. /FEA=mRNA /GEN=KIAA1103 /PROD=KIAA1103 protein /DB_XREF=gi:5689542 /UG=Hs.173159 transforming, acidic coiled-coil containing protein 1 AB029026 transforming, acidic coiled-coil containing protein 1 TACC1 6867 NM_001122824 /// NM_001146216 /// NM_006283 /// XM_005273622 /// XM_005273624 /// XM_005273625 /// XM_005273626 /// XM_005273627 /// XM_005273628 /// XM_005273629 /// XM_005273630 /// XM_005273631 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 217434_at Y10259 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y10259.1 /DEF=H.sapiens ACTH receptor mRNA 3UTR. /FEA=mRNA /DB_XREF=gi:2230860 /UG=Hs.274501 H.sapiens ACTH receptor mRNA 3UTR Y10259 melanocortin 2 receptor (adrenocorticotropic hormone) MC2R 4158 NM_000529 /// NM_001291911 0001890 // placenta development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004978 // corticotropin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217435_x_at Y15916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15916.1 /DEF=Homo sapiens mRNA for chimaeric transcript of collagen type 1 alpha 1 and platelet derived growth factor beta, 189 bp. /FEA=mRNA /PROD=COL1A1 and PDGFB fusion transcript /DB_XREF=gi:3288488 /UG=Hs.172928 collagen, type I, alpha 1 Y15916 217436_x_at M80469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M80469 /DEF=Human MHC class I HLA-J gene, exons 1-8 and complete cds /FEA=mRNA /DB_XREF=gi:188483 /UG=Hs.85242 major histocompatibility complex, class I, J (pseudogene) M80469 major histocompatibility complex, class I, J (pseudogene) HLA-J 3137 NR_024240 217437_s_at AB029026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB029026.1 /DEF=Homo sapiens mRNA for KIAA1103 protein, partial cds. /FEA=mRNA /GEN=KIAA1103 /PROD=KIAA1103 protein /DB_XREF=gi:5689542 /UG=Hs.173159 transforming, acidic coiled-coil containing protein 1 AB029026 transforming, acidic coiled-coil containing protein 1 TACC1 6867 NM_001122824 /// NM_001146216 /// NM_006283 /// XM_005273622 /// XM_005273624 /// XM_005273625 /// XM_005273626 /// XM_005273627 /// XM_005273628 /// XM_005273629 /// XM_005273630 /// XM_005273631 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 217438_at D25272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D25272.1 /DEF=Homo sapiens mRNA, clone:RES4-16. /FEA=mRNA /DB_XREF=gi:464187 /UG=Hs.174225 Homo sapiens mRNA, clone:RES4-16 D25272 217439_at AL122122 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL122122.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L098 (from clone DKFZp434L098). /FEA=mRNA /DB_XREF=gi:6102949 /UG=Hs.274559 Homo sapiens mRNA; cDNA DKFZp434L098 (from clone DKFZp434L098) AL122122 uncharacterized LOC101928278 LOC101928278 101928278 XR_241410 /// XR_249302 /// XR_251279 217440_at AL049342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049342.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566A193 (from clone DKFZp566A193). /FEA=mRNA /DB_XREF=gi:4500128 /UG=Hs.274506 Homo sapiens mRNA; cDNA DKFZp566A193 (from clone DKFZp566A193) AL049342 217441_at AK023664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023664.1 /DEF=Homo sapiens cDNA FLJ13602 fis, clone PLACE1010089, highly similar to Homo sapiens mRNA for KIAA1097 protein. /FEA=mRNA /DB_XREF=gi:10435655 /UG=Hs.173694 KIAA1097 protein AK023664 ubiquitin specific peptidase 33 USP33 23032 NM_015017 /// NM_201624 /// NM_201626 /// XM_005270648 /// XM_005270649 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from mutant phenotype /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030891 // VCB complex // traceable author statement /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217442_at AL050219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050219.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586J1623 (from clone DKFZp586J1623). /FEA=mRNA /DB_XREF=gi:4884460 /UG=Hs.274514 Homo sapiens mRNA; cDNA DKFZp586J1623 (from clone DKFZp586J1623) AL050219 CADM3 antisense RNA 1 CADM3-AS1 100131825 NR_037870 217443_at AL080152 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080152.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F104 (from clone DKFZp434F104). /FEA=mRNA /DB_XREF=gi:5262607 /UG=Hs.274516 Homo sapiens mRNA; cDNA DKFZp434F104 (from clone DKFZp434F104) AL080152 uncharacterized LOC101927792 LOC101927792 101927792 XR_243463 /// XR_248221 /// XR_253560 217444_at AL080086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080086.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564J1762 (from clone DKFZp564J1762). /FEA=mRNA /DB_XREF=gi:5262502 /UG=Hs.274538 Homo sapiens mRNA; cDNA DKFZp564J1762 (from clone DKFZp564J1762) AL080086 RP5-1184F4.5 217445_s_at AF008655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF008655.1 /DEF=Homo sapiens GARS-AIRS-GART mRNA, partial cds. /FEA=mRNA /PROD=GARS-AIRS-GART /DB_XREF=gi:2459950 /UG=Hs.82285 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase AF008655 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART 2618 NM_000819 /// NM_001136005 /// NM_001136006 /// NM_175085 /// XM_005260941 /// XM_006723988 /// XM_006723989 /// XM_006723990 0003360 // brainstem development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004637 // phosphoribosylamine-glycine ligase activity // inferred from electronic annotation /// 0004641 // phosphoribosylformylglycinamidine cyclo-ligase activity // inferred from electronic annotation /// 0004644 // phosphoribosylglycinamide formyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016742 // hydroxymethyl-, formyl- and related transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217446_x_at AL080160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL080160.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434M054 (from clone DKFZp434M054). /FEA=mRNA /DB_XREF=gi:5262622 /UG=Hs.274517 Homo sapiens mRNA; cDNA DKFZp434M054 (from clone DKFZp434M054) AL080160 217447_at X98405 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X98405.1 /DEF=H.sapiens mRNA for myelin associated glycoprotein, S-MAG. /FEA=mRNA /GEN=S-MAG /PROD=myelin associated glycoprotein /DB_XREF=gi:1403054 /UG=Hs.1780 myelin associated glycoprotein X98405 myelin associated glycoprotein MAG 4099 NM_001199216 /// NM_002361 /// NM_080600 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation 217448_s_at AL117508 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117508.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434G1835 (from clone DKFZp434G1835). /FEA=mRNA /DB_XREF=gi:5912018 /UG=Hs.274524 Homo sapiens mRNA; cDNA DKFZp434G1835 (from clone DKFZp434G1835) AL117508 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217449_at AL137284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137284.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434D1516 (from clone DKFZp434D1516). /FEA=mRNA /DB_XREF=gi:6807739 /UG=Hs.274572 Homo sapiens mRNA; cDNA DKFZp434D1516 (from clone DKFZp434D1516) AL137284 217450_at AF053356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF053356 /DEF=Homo sapiens chromosome 7q22 sequence /FEA=CDS_11 /DB_XREF=gi:3135305 /UG=Hs.181516 insulin receptor substrate 3-like AF053356 ArfGAP with FG repeats 2 AGFG2 3268 NM_006076 /// XM_005250306 /// XM_006715958 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217451_at AF042162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF042162 /DEF=Homo sapiens cytochrome c oxidase subunit Va (COX5AP1) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3861483 /UG=Hs.278595 cytochrome c oxidase subunit Va pseudogene 1 AF042162 RP11-665C16.8 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217452_s_at Y15014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Y15014.1 /DEF=Homo sapiens mRNA for UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta- galactosyltransferase. /FEA=mRNA /PROD=UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase /DB_XREF=gi:2791314 /UG=Hs.181353 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 Y15014 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 B3GALT2 8707 NM_003783 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 217453_at AL133089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133089.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E2028 (from clone DKFZp434E2028). /FEA=mRNA /DB_XREF=gi:6453541 /UG=Hs.274562 Homo sapiens mRNA; cDNA DKFZp434E2028 (from clone DKFZp434E2028) AL133089 217454_at AL034450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034450 /DEF=Human DNA sequence from clone 115K14 on chromosome Xq22.3-23 Contains high mobility group protein 2a, ESTs, STS /FEA=mRNA /DB_XREF=gi:4210359 /UG=Hs.194749 Human DNA sequence from clone 115K14 on chromosome Xq22.3-23 Contains high mobility group protein 2a, ESTs, STS AL034450 high mobility group box 3 pseudogene 30 /// HMGB3P30 /// HMGB3P30 217455_s_at AF184174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF184174 /DEF=Homo sapiens somatostatin receptor 2 (SSTR2) gene, complete cds, alternatively spliced /FEA=CDS_2 /DB_XREF=gi:7229402 /UG=Hs.184841 somatostatin receptor 2 AF184174 somatostatin receptor 2 SSTR2 6752 NM_001050 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038170 // somatostatin signaling pathway // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004994 // somatostatin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 217456_x_at M31183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M31183.1 /DEF=Homo sapiens (cosmid clone cd3.3) MHC class I HLA-B51 mRNA, 3 end of cds. /FEA=mRNA /GEN=HLA-B /PROD=MHC class I lymphocyte antigen /DB_XREF=gi:601851 /UG=Hs.181392 major histocompatibility complex, class I, E M31183 major histocompatibility complex, class I, E HLA-E 3133 NM_005516 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002476 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib // inferred from direct assay /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002717 // positive regulation of natural killer cell mediated immunity // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay 217457_s_at X63465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63465.1 /DEF=H.sapiens hGDS mRNA for smg GDS. /FEA=CDS /GEN=hGDS /PROD=smg GDS /DB_XREF=gi:32079 /UG=Hs.7940 RAP1, GTP-GDP dissociation stimulator 1 X63465 RAP1, GTP-GDP dissociation stimulator 1 RAP1GDS1 5910 NM_001100426 /// NM_001100427 /// NM_001100428 /// NM_001100429 /// NM_001100430 /// NM_021159 /// XM_006714284 /// XM_006714285 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0031034 // myosin filament assembly // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype 0000221 // vacuolar proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 217458_at AL137435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137435.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G0924 (from clone DKFZp761G0924). /FEA=mRNA /DB_XREF=gi:6807994 /UG=Hs.274577 Homo sapiens mRNA; cDNA DKFZp761G0924 (from clone DKFZp761G0924) AL137435 217459_at AL137292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137292.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L1016 (from clone DKFZp434L1016). /FEA=mRNA /DB_XREF=gi:6807752 /UG=Hs.274573 Homo sapiens mRNA; cDNA DKFZp434L1016 (from clone DKFZp434L1016) AL137292 217460_at X63759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X63759.1 /DEF=H.sapiens hTNP2 gene for transition protein 2. /FEA=mRNA /GEN=hTNP2 /PROD=transition protein 2 /DB_XREF=gi:505389 /UG=Hs.2748 transition protein 2 (during histone to protamine replacement) X63759 transition protein 2 (during histone to protamine replacement) TNP2 7142 NM_005425 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217461_x_at M90355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M90355 /DEF=Human BTF3 protein homologue gene, complete cds /FEA=CDS /DB_XREF=gi:1435190 /UG=Hs.181966 basic transcription factor 3, like 2 M90355 basic transcription factor 3 pseudogene 12 /// BTF3P12 /// BTF3P12 217462_at AC004770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004770 /DEF=Homo sapiens chromosome 11, BAC CIT-HSP-311e8 (BC269730) containing the hFEN1 gene /FEA=CDS_1 /DB_XREF=gi:3212836 /UG=Hs.184640 chromosome 11open reading frame 9 AC004770 myelin regulatory factor MYRF 745 NM_001127392 /// NM_013279 /// XM_005274222 /// XM_005274223 /// XM_005274224 /// XM_005274225 /// XM_005274226 /// XM_005274227 /// XM_005274228 /// XM_005274229 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from sequence or structural similarity /// 0022010 // central nervous system myelination // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217463_s_at AC004770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004770 /DEF=Homo sapiens chromosome 11, BAC CIT-HSP-311e8 (BC269730) containing the hFEN1 gene /FEA=CDS_1 /DB_XREF=gi:3212836 /UG=Hs.184640 chromosome 11open reading frame 9 AC004770 myelin regulatory factor MYRF 745 NM_001127392 /// NM_013279 /// XM_005274222 /// XM_005274223 /// XM_005274224 /// XM_005274225 /// XM_005274226 /// XM_005274227 /// XM_005274228 /// XM_005274229 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from sequence or structural similarity /// 0022010 // central nervous system myelination // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217464_at L48784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L48784 /DEF=050 Homo sapiens cDNA /FEA=mRNA /DB_XREF=gi:1066715 /UG=Hs.182426 ribosomal protein S2 L48784 217465_at AK001291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001291.1 /DEF=Homo sapiens cDNA FLJ10429 fis, clone NT2RP1000413, highly similar to Homo sapiens mRNA for KIAA0587 protein. /FEA=mRNA /DB_XREF=gi:7022454 /UG=Hs.278411 NCK-associated protein 1 AK001291 NCK-associated protein 1 NCKAP1 10787 NM_013436 /// NM_205842 /// XM_006712200 /// XM_006712201 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007354 // zygotic determination of anterior/posterior axis, embryo // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007492 // endoderm development // inferred from electronic annotation /// 0008078 // mesodermal cell migration // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030950 // establishment or maintenance of actin cytoskeleton polarity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045175 // basal protein localization // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay 217466_x_at L48784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:L48784 /DEF=050 Homo sapiens cDNA /FEA=mRNA /DB_XREF=gi:1066715 /UG=Hs.182426 ribosomal protein S2 L48784 ribosomal protein S2 /// small nucleolar RNA, H/ACA box 64 RPS2 /// SNORA64 6187 /// 26784 NM_002952 /// NR_002326 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051347 // positive regulation of transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217467_at M90356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M90356 /DEF=Human BTF3 protein homologue gene, complete cds /FEA=CDS /DB_XREF=gi:179575 /UG=Hs.181967 basic transcription factor 3, like 3 M90356 basic transcription factor 3 pseudogene 13 /// BTF3P13 /// BTF3P13 217468_at X07618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X07618.1 /DEF=Human mRNA for cytochrome P450 db1 variant a. /FEA=mRNA /DB_XREF=gi:30452 /UG=Hs.274598 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 7a (pseudogene) X07618 cytochrome P450, family 2, subfamily D, polypeptide 6 CYP2D6 1565 NM_000106 /// NM_001025161 /// XM_005278354 /// XM_006724157 /// XM_006726317 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0009820 // alkaloid metabolic process // inferred from direct assay /// 0009822 // alkaloid catabolic process // inferred from direct assay /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0033076 // isoquinoline alkaloid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0051100 // negative regulation of binding // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0090350 // negative regulation of cellular organofluorine metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 217469_at X95746 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X95746.1 /DEF=H.sapiens immunoglobulin epsilon chain. /FEA=CDS /GEN=epsilon-FD /PROD=immunoglobulin epsilon chain /DB_XREF=gi:1514574 /UG=Hs.274600 H.sapiens immunoglobulin epsilon chain X95746 immunoglobulin heavy locus IGH 3492 0001895 // retina homeostasis // inferred from expression pattern /// 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071748 // monomeric IgA immunoglobulin complex // inferred from direct assay /// 0071751 // secretory IgA immunoglobulin complex // inferred from direct assay /// 0071752 // secretory dimeric IgA immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0003823 // antigen binding // non-traceable author statement /// 0034987 // immunoglobulin receptor binding // inferred from direct assay 217470_at AL157490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157490.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F1011 (from clone DKFZp434F1011). /FEA=mRNA /DB_XREF=gi:7018535 /UG=Hs.274589 Homo sapiens mRNA; cDNA DKFZp434F1011 (from clone DKFZp434F1011) AL157490 217471_at AL117652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117652.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1324 (from clone DKFZp586B1324). /FEA=mRNA /DB_XREF=gi:5912244 /UG=Hs.278334 Homo sapiens mRNA; cDNA DKFZp586B1324 (from clone DKFZp586B1324) AL117652 uncharacterized LOC101928104 LOC101928104 101928104 NR_110825 /// XR_243746 /// XR_248413 /// XR_253721 217472_at J02963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:J02963.1 /DEF=Human platelet glycoprotein IIb mRNA, 3 end. /FEA=mRNA /GEN=ITGA2B /DB_XREF=gi:190069 /UG=Hs.785 integrin, alpha 2b (platelet glycoprotein IIb of IIbIIIa complex, antigen CD41B) J02963 217473_x_at AF229163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229163 /DEF=Homo sapiens natural resistance-associated macrophage protein 1 (SLC11A1) gene, complete cds, alternatively spliced; and nuclear LIM interactor-interacting factor (NLI-IF) gene, complete cds /FEA=mRNA_3 /DB_XREF=gi:10257408 /UG=Hs.182611 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 AF229163 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 SLC11A1 6556 NM_000578 /// NM_001032220 /// XM_005246793 /// XM_005246794 /// XM_006712709 /// XM_006712710 /// XM_006712711 /// XR_427107 /// XR_427108 /// XR_427109 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0001818 // negative regulation of cytokine production // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002309 // T cell proliferation involved in immune response // inferred from sequence or structural similarity /// 0002369 // T cell cytokine production // inferred from sequence or structural similarity /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006876 // cellular cadmium ion homeostasis // inferred from genetic interaction /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0006909 // phagocytosis // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0015707 // nitrite transport // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032623 // interleukin-2 production // inferred from sequence or structural similarity /// 0032632 // interleukin-3 production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042116 // macrophage activation // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043091 // L-arginine import // inferred from sequence or structural similarity /// 0045342 // MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045730 // respiratory burst // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048002 // antigen processing and presentation of peptide antigen // inferred from sequence or structural similarity /// 0048255 // mRNA stabilization // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055072 // iron ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from sequence or structural similarity /// 0070574 // cadmium ion transmembrane transport // inferred from genetic interaction /// 0070839 // divalent metal ion export // inferred from sequence or structural similarity /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0031902 // late endosome membrane // traceable author statement /// 0070821 // tertiary granule membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046915 // transition metal ion transmembrane transporter activity // inferred from genetic interaction /// 0051139 // metal ion:proton antiporter activity // inferred from genetic interaction 217474_at AL117652 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117652.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1324 (from clone DKFZp586B1324). /FEA=mRNA /DB_XREF=gi:5912244 /UG=Hs.278334 Homo sapiens mRNA; cDNA DKFZp586B1324 (from clone DKFZp586B1324) AL117652 217475_s_at AC002073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002073 /DEF=Human PAC clone RP3-515N1 from 22q11.2-q22 /FEA=CDS_1 /DB_XREF=gi:2078469 /UG=Hs.278027 LIM domain kinase 2 AC002073 LIM domain kinase 2 LIMK2 3985 NM_001031801 /// NM_005569 /// NM_016733 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0042325 // regulation of phosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217476_at M24900 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M24900.1 /DEF=Human triiodothyronine recptor (THRA1, ear1), and ear2 genes, last 2 exons each. /FEA=mRNA /GEN=THRA1 /PROD=triiodothyronine receptor; triiodothyronine receptor; triiodothyronine receptor /DB_XREF=gi:537515 /UG=Hs.276916 nuclear receptor subfamily 1, group D, member 1 M24900 nuclear receptor subfamily 1, group D, member 1 /// thyroid hormone receptor, alpha NR1D1 /// THRA 7067 /// 9572 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_021724 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 217477_at U78581 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U78581.1 /DEF=Human type I phosphatidylinositol-4-phosphate 5-kinase beta (STM7) mRNA, partial cds. /FEA=mRNA /GEN=STM7 /PROD=type I phosphatidylinositol-4-phosphate 5-kinasebeta /DB_XREF=gi:1743882 /UG=Hs.78406 phosphatidylinositol-4-phosphate 5-kinase, type I, beta U78581 phosphatidylinositol-4-phosphate 5-kinase, type I, beta PIP5K1B 8395 NM_001031687 /// NM_001278253 /// NM_003558 /// XM_005252261 /// XM_005252262 /// XM_006717300 /// XM_006717301 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // non-traceable author statement 0001931 // uropod // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 217478_s_at X76775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X76775 /DEF=H.sapiens HLA-DMA gene /FEA=mRNA_1 /DB_XREF=gi:512468 /UG=Hs.77522 major histocompatibility complex, class II, DM alpha X76775 major histocompatibility complex, class II, DM alpha HLA-DMA 3108 NM_006120 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay 217479_at AL110201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110201.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1622 (from clone DKFZp586F1622). /FEA=mRNA /DB_XREF=gi:5817120 /UG=Hs.278435 Homo sapiens mRNA; cDNA DKFZp586F1622 (from clone DKFZp586F1622) AL110201 217480_x_at M20812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M20812 /DEF=Human kappa-immunoglobulin germline pseudogene (cos118) variable region (subgroup V kappa I) /FEA=mRNA /DB_XREF=gi:185958 /UG=Hs.278448 Human kappa-immunoglobulin germline pseudogene (cos118) variable region (subgroup V kappa I) M20812 /// /// immunoglobulin kappa variable 1/OR-1 (pseudogene) /// /// immunoglobulin kappa variable 1/OR10-1 (pseudogene) /// /// immunoglobulin kappa variable 1/OR2-2 (pseudogene) AC128677.4 /// CH17-132F21.1 /// IGKV1OR-1 /// IGKV1OR-1 /// IGKV1OR10-1 /// IGKV1OR10-1 /// IGKV1OR2-2 0005515 // protein binding // inferred from electronic annotation 217481_x_at AL110201 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110201.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586F1622 (from clone DKFZp586F1622). /FEA=mRNA /DB_XREF=gi:5817120 /UG=Hs.278435 Homo sapiens mRNA; cDNA DKFZp586F1622 (from clone DKFZp586F1622) AL110201 RP11-680C21.1 217482_at AK021987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021987.1 /DEF=Homo sapiens cDNA FLJ11925 fis, clone HEMBB1000354. /FEA=mRNA /DB_XREF=gi:10433296 /UG=Hs.191158 Homo sapiens cDNA FLJ11925 fis, clone HEMBB1000354 AK021987 217483_at AF254357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF254357.1 /DEF=Homo sapiens prostate-specific membrane antigen PSM mRNA, exon 6 alternative splice variant, partial cds. /FEA=mRNA /PROD=prostate-specific membrane antigen PSM /DB_XREF=gi:7963794 /UG=Hs.1915 folate hydrolase (prostate-specific membrane antigen) 1 AF254357 folate hydrolase (prostate-specific membrane antigen) 1 FOLH1 2346 NM_001014986 /// NM_001193471 /// NM_001193472 /// NM_001193473 /// NM_004476 /// XM_005252839 0006508 // proteolysis // non-traceable author statement /// 0006760 // folic acid-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217484_at X14362 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X14362.1 /DEF=Human CR1 mRNA for C3bC4b receptor secreted form. /FEA=mRNA /DB_XREF=gi:30197 /UG=Hs.193716 complement component (3b4b) receptor 1, including Knops blood group system X14362 complement component (3b/4b) receptor 1 (Knops blood group) CR1 1378 NM_000573 /// NM_000651 /// XM_005273064 /// XM_006711166 /// XM_006711167 /// XM_006711168 0002376 // immune system process // inferred from electronic annotation /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045957 // negative regulation of complement activation, alternative pathway // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900005 // positive regulation of serine-type endopeptidase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001851 // complement component C3b binding // inferred from direct assay /// 0001855 // complement component C4b binding // inferred from direct assay /// 0001861 // complement component C4b receptor activity // inferred from direct assay /// 0004877 // complement component C3b receptor activity // inferred from direct assay 217485_x_at D38435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38435.1 /DEF=Homo sapiens hPMS3 mRNA, partial cds. /FEA=mRNA /GEN=hPMS3 /DB_XREF=gi:600590 /UG=Hs.278466 postmeiotic segregation increased 2-like 1 D38435 postmeiotic segregation increased 2 pseudogene 1 PMS2P1 5379 NM_005394 /// NR_003613 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 217486_s_at AF161412 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF161412.1 /DEF=Homo sapiens HSPC294 mRNA, partial cds. /FEA=mRNA /PROD=HSPC294 /DB_XREF=gi:6841237 /UG=Hs.4014 KIAA0946 protein; Huntingtin interacting protein H AF161412 zinc finger, DHHC-type containing 17 ZDHHC17 23390 NM_015336 /// XM_005268749 /// XM_005268750 /// XM_005268751 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from direct assay /// 0018345 // protein palmitoylation // inferred from direct assay /// 0042953 // lipoprotein transport // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015095 // magnesium ion transmembrane transporter activity // inferred from direct assay /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217487_x_at AF254357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF254357.1 /DEF=Homo sapiens prostate-specific membrane antigen PSM mRNA, exon 6 alternative splice variant, partial cds. /FEA=mRNA /PROD=prostate-specific membrane antigen PSM /DB_XREF=gi:7963794 /UG=Hs.1915 folate hydrolase (prostate-specific membrane antigen) 1 AF254357 folate hydrolase (prostate-specific membrane antigen) 1 /// folate hydrolase 1B FOLH1 /// FOLH1B 2346 /// 219595 NM_001014986 /// NM_001193471 /// NM_001193472 /// NM_001193473 /// NM_004476 /// NM_153696 /// XM_005252839 /// XM_006718776 0006508 // proteolysis // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006760 // folic acid-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217488_x_at D38437 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:D38437.1 /DEF=Homo sapiens hPMS5 mRNA, partial cds. /FEA=mRNA /GEN=hPMS5 /DB_XREF=gi:600592 /UG=Hs.278467 postmeiotic segregation increased 2-like 3 D38437 postmeiotic segregation increased 2 pseudogene 3 PMS2P3 5387 NM_001003686 /// NM_005395 /// NR_028059 0006298 // mismatch repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0032300 // mismatch repair complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation 217489_s_at S72848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S72848.1 /DEF=sIL-6R=Soluble interleukin-6 receptor {alternatively spliced} human, peripheral blood mononuclear cells (PBMC), mRNA Partial, 162 nt. /FEA=CDS /GEN=sIL-6R /PROD=Soluble interleukin-6 receptor /DB_XREF=gi:633862 /UG=Hs.193400 interleukin 6 receptor S72848 interleukin 6 receptor IL6R 3570 NM_000565 /// NM_001206866 /// NM_181359 /// XM_005245139 /// XM_005245140 /// XM_006711298 /// XM_006711299 0002384 // hepatic immune response // traceable author statement /// 0002446 // neutrophil mediated immunity // inferred by curator /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002690 // positive regulation of leukocyte chemotaxis // inferred by curator /// 0002690 // positive regulation of leukocyte chemotaxis // traceable author statement /// 0006953 // acute-phase response // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010536 // positive regulation of activation of Janus kinase activity // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0031018 // endocrine pancreas development // inferred by curator /// 0031018 // endocrine pancreas development // inferred from mutant phenotype /// 0032717 // negative regulation of interleukin-8 production // inferred from expression pattern /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032966 // negative regulation of collagen biosynthetic process // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from expression pattern /// 0050830 // defense response to Gram-positive bacterium // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070102 // interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005896 // interleukin-6 receptor complex // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from mutant phenotype /// 0004915 // interleukin-6 receptor activity // inferred from direct assay /// 0005138 // interleukin-6 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019981 // interleukin-6 binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0070119 // ciliary neurotrophic factor binding // inferred from physical interaction 217490_at AL049301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049301.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073). /FEA=mRNA /DB_XREF=gi:4500067 /UG=Hs.278577 Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) AL049301 217491_x_at AF042165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF042165 /DEF=Homo sapiens cytochrome c oxidase subunit VIIc (COX7CP1) pseudogene, complete sequence /FEA=CDS /DB_XREF=gi:3861486 /UG=Hs.278494 cytochrome c oxidase subunit VIIc pseudogene 1 AF042165 cytochrome c oxidase subunit VIIc COX7C 1350 NM_001867 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 217492_s_at AF023139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF023139.1 /DEF=Homo sapiens multiple advanced cancers protein (MMAC1) pseudo mRNA, partial sequence. /FEA=mRNA /GEN=MMAC1 /DB_XREF=gi:2749973 /UG=Hs.278506 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1 AF023139 phosphatase and tensin homolog /// phosphatase and tensin homolog pseudogene 1 (functional) PTEN /// PTENP1 5728 /// 11191 NM_000314 /// NR_023917 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement 217493_x_at AL136967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136967 /DEF=Human DNA sequence from clone RP1-149M18 on chromosome 6 Contains ESTs, STSs, GSSs and CpG islands. Contains the natural killer cell p44 related gene (NKp44RG) with three isoforms /FEA=mRNA_2 /DB_XREF=gi:9501164 /UG=Hs.194721 lymphocyte antigen 95 (activating NK-receptor ; NK-p44) AL136967 natural cytotoxicity triggering receptor 2 NCR2 9436 NM_001199509 /// NM_001199510 /// NM_004828 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 217494_s_at AF023139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF023139.1 /DEF=Homo sapiens multiple advanced cancers protein (MMAC1) pseudo mRNA, partial sequence. /FEA=mRNA /GEN=MMAC1 /DB_XREF=gi:2749973 /UG=Hs.278506 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1 AF023139 217495_x_at X15943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X15943 /DEF=Huamn calcitoninalpha-CGRP gene /FEA=mRNA /DB_XREF=gi:29613 /UG=Hs.37058 calcitonincalcitonin-related polypeptide, alpha X15943 calcitonin-related polypeptide alpha CALCA 796 NM_001033952 /// NM_001033953 /// NM_001741 /// XM_005253134 0001935 // endothelial cell proliferation // inferred from direct assay /// 0001944 // vasculature development // inferred from direct assay /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from direct assay /// 0001984 // vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032730 // positive regulation of interleukin-1 alpha production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from direct assay /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031716 // calcitonin receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 217496_s_at AA918442 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA918442 /FEA=EST /DB_XREF=gi:3058332 /DB_XREF=est:om38b01.s1 /CLONE=IMAGE:1543273 /UG=Hs.326641 Homo sapiens insulin-degrading enzyme (IDE), mRNA AA918442 insulin-degrading enzyme IDE 3416 NM_001165946 /// NM_004969 /// XM_005269766 /// XM_005269769 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0008340 // determination of adult lifespan // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010992 // ubiquitin homeostasis // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 1901142 // insulin metabolic process // inferred from direct assay /// 1901143 // insulin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031626 // beta-endorphin binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217497_at AW613387 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW613387 /FEA=EST /DB_XREF=gi:7318573 /DB_XREF=est:hh71e04.x1 /CLONE=IMAGE:2968254 /UG=Hs.278541 ESTs, Moderately similar to TYPH_HUMAN THYMIDINE PHOSPHORYLASE PRECURSOR H.sapiens AW613387 thymidine phosphorylase TYMP 1890 NM_001113755 /// NM_001113756 /// NM_001257988 /// NM_001257989 /// NM_001953 0000002 // mitochondrial genome maintenance // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // inferred from electronic annotation /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030016 // myofibril // inferred from direct assay 0004645 // phosphorylase activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0009032 // thymidine phosphorylase activity // inferred from electronic annotation /// 0016154 // pyrimidine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 217498_at BG389073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG389073 /FEA=EST /DB_XREF=gi:13282519 /DB_XREF=est:602414868F1 /CLONE=IMAGE:4523201 /UG=Hs.151010 ESTs BG389073 growth differentiation factor 11 GDF11 10220 NM_005811 /// XM_006719193 /// XM_006719194 0001501 // skeletal system development // traceable author statement /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0021512 // spinal cord anterior/posterior patterning // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 217499_x_at AW874308 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW874308 /FEA=EST /DB_XREF=gi:8008445 /DB_XREF=est:hq04g08.x1 /CLONE=IMAGE:3118430 /UG=Hs.332964 olfactory receptor, family 7, subfamily E, member 38 pseudogene AW874308 olfactory receptor, family 7, subfamily E, member 37 pseudogene OR7E37P 100506759 NR_002163 217500_at R27378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R27378 /FEA=EST /DB_XREF=gi:783513 /DB_XREF=est:yh53g11.r1 /CLONE=IMAGE:133508 /UG=Hs.322426 ESTs, Moderately similar to TIAR_HUMAN NUCLEOLYSIN TIAR H.sapiens R27378 TIA1 cytotoxic granule-associated RNA binding protein-like 1 TIAL1 7073 NM_001033925 /// NM_003252 /// XM_005270108 /// XM_005270109 /// XM_005270110 /// XM_006717959 /// XR_428715 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217501_at AI339732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI339732 /FEA=EST /DB_XREF=gi:4076659 /DB_XREF=est:qq42f05.x1 /CLONE=IMAGE:1935201 /UG=Hs.309763 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI339732 cytosolic iron-sulfur assembly component 1 CIAO1 9391 NM_004804 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016226 // iron-sulfur cluster assembly // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay 217502_at BE888744 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE888744 /FEA=EST /DB_XREF=gi:10345354 /DB_XREF=est:601513656F1 /CLONE=IMAGE:3915133 /UG=Hs.169274 ESTs, Highly similar to IFT2_HUMAN INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2 H.sapiens BE888744 interferon-induced protein with tetratricopeptide repeats 2 IFIT2 3433 NM_001547 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217503_at AA203487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA203487 /FEA=EST /DB_XREF=gi:1799460 /DB_XREF=est:zx53d03.r1 /CLONE=IMAGE:446213 /UG=Hs.314363 ESTs AA203487 serine/threonine kinase 17b STK17B 9262 NM_004226 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217504_at AA099357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA099357 /FEA=EST /DB_XREF=gi:1645257 /DB_XREF=est:zk85c01.s1 /CLONE=IMAGE:489600 /UG=Hs.15780 ATP-binding cassette, sub-family A (ABC1), member 6 AA099357 ATP-binding cassette, sub-family A (ABC1), member 6 ABCA6 23460 NM_080284 /// NM_172346 /// XM_006721790 /// XM_006721791 /// XM_006721792 /// XM_006721793 /// XR_429879 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 217505_at BG403790 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG403790 /FEA=EST /DB_XREF=gi:13297238 /DB_XREF=est:602419627F1 /CLONE=IMAGE:4526599 /UG=Hs.158154 ESTs BG403790 kelch-like family member 23 /// PHOSPHO2-KLHL23 readthrough KLHL23 /// PHOSPHO2-KLHL23 151230 /// 100526832 NM_001199290 /// NM_144711 0005515 // protein binding // inferred from electronic annotation 217506_at H49382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H49382 /FEA=EST /DB_XREF=gi:989223 /DB_XREF=est:yq19b06.s1 /CLONE=IMAGE:274115 /UG=Hs.124984 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens H49382 217507_at AI346187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346187 /FEA=EST /DB_XREF=gi:4083393 /DB_XREF=est:qp49c02.x1 /CLONE=IMAGE:1926338 /UG=Hs.265982 ESTs, Weakly similar to ALUE_HUMAN !!!! ALU CLASS E WARNING ENTRY !!! H.sapiens AI346187 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 SLC11A1 6556 NM_000578 /// NM_001032220 /// XM_005246793 /// XM_005246794 /// XM_006712709 /// XM_006712710 /// XM_006712711 /// XR_427107 /// XR_427108 /// XR_427109 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0001818 // negative regulation of cytokine production // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002309 // T cell proliferation involved in immune response // inferred from sequence or structural similarity /// 0002369 // T cell cytokine production // inferred from sequence or structural similarity /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006876 // cellular cadmium ion homeostasis // inferred from genetic interaction /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0006909 // phagocytosis // inferred from sequence or structural similarity /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006955 // immune response // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0009617 // response to bacterium // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0015707 // nitrite transport // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032623 // interleukin-2 production // inferred from sequence or structural similarity /// 0032632 // interleukin-3 production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042116 // macrophage activation // inferred from sequence or structural similarity /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043091 // L-arginine import // inferred from sequence or structural similarity /// 0045342 // MHC class II biosynthetic process // inferred from sequence or structural similarity /// 0045730 // respiratory burst // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048002 // antigen processing and presentation of peptide antigen // inferred from sequence or structural similarity /// 0048255 // mRNA stabilization // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050829 // defense response to Gram-negative bacterium // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055072 // iron ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from sequence or structural similarity /// 0070574 // cadmium ion transmembrane transport // inferred from genetic interaction /// 0070839 // divalent metal ion export // inferred from sequence or structural similarity /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from direct assay /// 0031902 // late endosome membrane // traceable author statement /// 0070821 // tertiary granule membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046915 // transition metal ion transmembrane transporter activity // inferred from genetic interaction /// 0051139 // metal ion:proton antiporter activity // inferred from genetic interaction 217508_s_at BE783279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE783279 /FEA=EST /DB_XREF=gi:10204477 /DB_XREF=est:601470835F1 /CLONE=IMAGE:3873801 /UG=Hs.33862 ESTs BE783279 chromosome 18 open reading frame 25 C18orf25 147339 NM_001008239 /// NM_145055 0008152 // metabolic process // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 217509_x_at BG151527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG151527 /FEA=EST /DB_XREF=gi:12663557 /DB_XREF=est:nac28d07.x1 /CLONE=IMAGE:3394597 /UG=Hs.128095 ESTs, Moderately similar to GLK5_HUMAN GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 5 PRECURSOR H.sapiens BG151527 glutamate receptor, ionotropic, kainate 5 GRIK5 2901 NM_002088 /// XM_005258821 /// XM_005258822 /// XM_006723169 /// XM_006723170 /// XR_243925 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0031630 // regulation of synaptic vesicle fusion to presynaptic membrane // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0051649 // establishment of localization in cell // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008328 // ionotropic glutamate receptor complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0032983 // kainate selective glutamate receptor complex // not recorded /// 0042734 // presynaptic membrane // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // inferred from electronic annotation /// 0015277 // kainate selective glutamate receptor activity // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 217510_at BE257838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE257838 /FEA=EST /DB_XREF=gi:9128318 /DB_XREF=est:601109422F1 /CLONE=IMAGE:3350164 /UG=Hs.66418 ESTs BE257838 cone-rod homeobox CRX 1406 NM_000554 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046534 // positive regulation of photoreceptor cell differentiation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from sequence or structural similarity /// 0043522 // leucine zipper domain binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217511_at W28828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W28828 /FEA=EST /DB_XREF=gi:1308776 /DB_XREF=est:52c6 /UG=Hs.155234 ESTs, Weakly similar to KRHU0 keratin 10, type I, cytoskeletal H.sapiens W28828 Kazal-type serine peptidase inhibitor domain 1 KAZALD1 81621 NM_030929 /// XM_005270193 /// XM_005270194 /// XR_246107 0001503 // ossification // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation 217512_at BG398937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG398937 /FEA=EST /DB_XREF=gi:13292385 /DB_XREF=est:602440589F1 /CLONE=IMAGE:4551478 /UG=Hs.289056 ESTs, Highly similar to 1312232A kininogen L,high MW H.sapiens BG398937 kininogen 1 KNG1 3827 NM_000893 /// NM_001102416 /// NM_001166451 0002576 // platelet degranulation // traceable author statement /// 0006939 // smooth muscle contraction // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0035810 // positive regulation of urine volume // traceable author statement /// 0035815 // positive regulation of renal sodium excretion // traceable author statement /// 0042311 // vasodilation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 217513_at BG334495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG334495 /FEA=EST /DB_XREF=gi:13140933 /DB_XREF=est:602461128F1 /CLONE=IMAGE:4577718 /UG=Hs.228201 ESTs, Moderately similar to AF118094 25 PRO1992 H.sapiens BG334495 mast cell immunoglobulin-like receptor 1 MILR1 284021 NM_001085423 /// NM_001291316 /// NM_001291317 /// XM_005276872 /// XM_005276873 /// XM_005276874 /// XM_005276875 /// XM_005276876 /// XM_005276877 /// XM_005276878 0033004 // negative regulation of mast cell activation // inferred from sequence or structural similarity /// 0043303 // mast cell degranulation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity 217514_at BF509345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF509345 /FEA=EST /DB_XREF=gi:11592709 /DB_XREF=est:UI-H-BI4-aox-c-11-0-UI.s1 /CLONE=IMAGE:3086229 /UG=Hs.6996 ESTs BF509345 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 ST8SIA5 29906 NM_013305 /// XM_005258250 /// XM_006722443 /// XM_006722444 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 217515_s_at AI391509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI391509 /FEA=EST /DB_XREF=gi:4217513 /DB_XREF=est:tg03d06.x1 /CLONE=IMAGE:2107691 /UG=Hs.328199 Homo sapiens calcium channel, voltage-dependent, L type, alpha 1S subunit (CACNA1S), mRNA AI391509 calcium channel, voltage-dependent, L type, alpha 1S subunit CACNA1S 779 NM_000069 /// XM_005245478 0001501 // skeletal system development // inferred from electronic annotation /// 0002074 // extraocular skeletal muscle development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0043501 // skeletal muscle adaptation // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0055001 // muscle cell development // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030315 // T-tubule // inferred from direct assay /// 0031674 // I band // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0008331 // high voltage-gated calcium channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217516_x_at BG149428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG149428 /FEA=EST /DB_XREF=gi:12661458 /DB_XREF=est:nad28e04.x1 /CLONE=IMAGE:3366990 /UG=Hs.328358 Homo sapiens armadillo repeat gene deletes in velocardiofacial syndrome (ARVCF), mRNA BG149428 armadillo repeat gene deleted in velocardiofacial syndrome ARVCF 421 NM_001670 /// XM_005261242 /// XM_005261243 /// XM_005261244 /// XM_006724243 /// XM_006724244 /// XM_006724245 /// XM_006724246 /// XM_006724247 /// XM_006724248 /// XM_006724249 /// XM_006724250 /// XM_006724251 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0009712 // catechol-containing compound metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045963 // negative regulation of dopamine metabolic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048609 // multicellular organismal reproductive process // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050668 // positive regulation of homocysteine metabolic process // inferred from electronic annotation 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0016206 // catechol O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217517_x_at AI886482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI886482 /FEA=EST /DB_XREF=gi:5591646 /DB_XREF=est:wn39e07.x1 /CLONE=IMAGE:2447844 /UG=Hs.236750 ESTs, Highly similar to serine kinase SRPK2 H.sapiens AI886482 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity 217518_at BF056029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056029 /FEA=EST /DB_XREF=gi:10809925 /DB_XREF=est:7k07f03.x1 /CLONE=IMAGE:3443836 /UG=Hs.174910 ESTs, Weakly similar to dysferlin H.sapiens BF056029 myoferlin MYOF 26509 NM_013451 /// NM_133337 /// XM_005269693 /// XM_005269694 /// XM_006717760 0001778 // plasma membrane repair // inferred from sequence or structural similarity /// 0006936 // muscle contraction // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from sequence or structural similarity 217519_at AI246331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI246331 /FEA=EST /DB_XREF=gi:3841728 /DB_XREF=est:qu39f10.x1 /CLONE=IMAGE:1967179 /UG=Hs.248999 ESTs AI246331 217520_x_at BG396614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG396614 /FEA=EST /DB_XREF=gi:13290062 /DB_XREF=est:602459468F1 /CLONE=IMAGE:4581928 /UG=Hs.154999 ESTs, Moderately similar to HERC2 H.sapiens BG396614 uncharacterized LOC101929232 /// PDCD6IP pseudogene 2 LOC101929232 /// PDCD6IPP2 646278 /// 101929232 NR_037599 /// XR_241731 /// XR_241732 /// XR_249736 /// XR_249737 /// XR_251743 /// XR_251744 217521_at N54942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N54942 /FEA=EST /DB_XREF=gi:1196262 /DB_XREF=est:yv38b08.s1 /CLONE=IMAGE:244983 /UG=Hs.276590 ESTs N54942 histidine ammonia-lyase HAL 3034 NM_001258333 /// NM_001258334 /// NM_002108 /// XM_005268821 0006547 // histidine metabolic process // inferred from electronic annotation /// 0006548 // histidine catabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019556 // histidine catabolic process to glutamate and formamide // inferred from electronic annotation /// 0019557 // histidine catabolic process to glutamate and formate // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004397 // histidine ammonia-lyase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016841 // ammonia-lyase activity // inferred from electronic annotation 217522_at AI206888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI206888 /FEA=EST /DB_XREF=gi:3765560 /DB_XREF=est:qr35a04.x1 /CLONE=IMAGE:1942830 /UG=Hs.154131 ESTs AI206888 potassium channel, subfamily V, member 2 KCNV2 169522 NM_133497 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation 217523_at AV700298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700298 /FEA=EST /DB_XREF=gi:10302269 /DB_XREF=est:AV700298 /CLONE=GKCBVGO5 /UG=Hs.285173 ESTs, Moderately similar to CD44_HUMAN CD44 ANTIGEN PRECURSOR H.sapiens AV700298 CD44 molecule (Indian blood group) CD44 960 NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 /// NM_001202555 /// NM_001202556 /// NM_001202557 /// XM_005253231 /// XM_005253232 /// XM_005253233 /// XM_005253234 /// XM_005253235 /// XM_005253238 /// XM_005253239 /// XM_005253240 /// XM_006718388 /// XM_006718389 /// XM_006718390 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051216 // cartilage development // inferred from expression pattern /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070487 // monocyte aggregation // inferred from mutant phenotype /// 1900625 // positive regulation of monocyte aggregation // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004415 // hyalurononglucosaminidase activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0005540 // hyaluronic acid binding // inferred from direct assay /// 0005540 // hyaluronic acid binding // non-traceable author statement 217524_x_at AA018923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA018923 /FEA=EST /DB_XREF=gi:1482314 /DB_XREF=est:ze58d03.s1 /CLONE=IMAGE:363173 /UG=Hs.261204 ESTs AA018923 217525_at AW305097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW305097 /FEA=EST /DB_XREF=gi:6717300 /DB_XREF=est:xv99d08.x1 /CLONE=IMAGE:2826639 /UG=Hs.47974 ESTs, Moderately similar to JC4969 pig-c protein H.sapiens AW305097 olfactomedin-like 1 OLFML1 283298 NM_198474 /// XM_005252878 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217526_at AI478300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478300 /FEA=EST /DB_XREF=gi:4371526 /DB_XREF=est:tm39e01.x1 /CLONE=IMAGE:2160504 /UG=Hs.192789 ESTs, Weakly similar to ALU6_HUMAN ALU SUBFAMILY SP SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI478300 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein NFATC2IP 84901 NM_032815 0001816 // cytokine production // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217527_s_at AI478300 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478300 /FEA=EST /DB_XREF=gi:4371526 /DB_XREF=est:tm39e01.x1 /CLONE=IMAGE:2160504 /UG=Hs.192789 ESTs, Weakly similar to ALU6_HUMAN ALU SUBFAMILY SP SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI478300 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein NFATC2IP 84901 NM_032815 0001816 // cytokine production // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217528_at BF003134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF003134 /FEA=EST /DB_XREF=gi:10703409 /DB_XREF=est:7g55f09.x1 /CLONE=IMAGE:3310409 /UG=Hs.72365 ESTs BF003134 chloride channel accessory 2 CLCA2 9635 NM_006536 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005254 // chloride channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation 217529_at BE547674 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE547674 /FEA=EST /DB_XREF=gi:9776319 /DB_XREF=est:601076255F1 /CLONE=IMAGE:3462325 /UG=Hs.204169 ESTs BE547674 ORAI calcium release-activated calcium modulator 2 ORAI2 80228 NM_001126340 /// NM_001271818 /// NM_001271819 /// NM_032831 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217530_at AW295295 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW295295 /FEA=EST /DB_XREF=gi:6701931 /DB_XREF=est:UI-H-BI2-aht-f-12-0-UI.s1 /CLONE=IMAGE:2728079 /UG=Hs.212522 ESTs, Highly similar to B48189 sodiumphosphate cotransport protein, renal cortex H.sapiens AW295295 solute carrier family 34 (type II sodium/phosphate contransporter), member 1 SLC34A1 6569 NM_001167579 /// NM_003052 /// XM_005265974 /// XM_005265975 0001503 // ossification // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0035864 // response to potassium ion // inferred from electronic annotation /// 0042431 // indole metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from direct assay /// 0046689 // response to mercury ion // inferred from direct assay /// 0046849 // bone remodeling // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0071107 // response to parathyroid hormone // inferred from electronic annotation /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from electronic annotation /// 0072734 // cellular response to staurosporine // inferred from electronic annotation /// 0097066 // response to thyroid hormone // inferred from electronic annotation /// 0097187 // dentinogenesis // inferred from electronic annotation /// 1901128 // gentamycin metabolic process // inferred from electronic annotation /// 1901652 // response to peptide // inferred from electronic annotation /// 1901684 // arsenate ion transmembrane transport // inferred from electronic annotation /// 2000120 // positive regulation of sodium-dependent phosphate transport // inferred from electronic annotation /// 2000187 // positive regulation of phosphate transmembrane transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // non-traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 217531_at AW301775 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301775 /FEA=EST /DB_XREF=gi:6711452 /DB_XREF=est:xr83e06.x1 /CLONE=IMAGE:2766754 /UG=Hs.254727 ESTs AW301775 217532_x_at AW268081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW268081 /FEA=EST /DB_XREF=gi:6655111 /DB_XREF=est:xr92e03.x1 /CLONE=IMAGE:2767612 /UG=Hs.193408 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens AW268081 217533_x_at AW268081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW268081 /FEA=EST /DB_XREF=gi:6655111 /DB_XREF=est:xr92e03.x1 /CLONE=IMAGE:2767612 /UG=Hs.193408 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens AW268081 PWWP domain containing 2A PWWP2A 114825 NM_001130864 /// NM_001267035 /// NM_052927 /// XM_005265807 /// XM_005265808 /// XM_005265809 /// XM_005265810 /// XM_005265811 /// XM_005265812 /// XM_005265813 /// XM_005265814 /// XM_006714817 /// XR_245271 /// XR_427800 0005515 // protein binding // inferred from physical interaction 217534_at AA845825 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA845825 /FEA=EST /DB_XREF=gi:2931965 /DB_XREF=est:ak85f12.s1 /CLONE=IMAGE:1414703 /UG=Hs.282721 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA845825 family with sequence similarity 49, member B FAM49B 51571 NM_001256763 /// NM_016623 /// NR_046359 /// NR_046360 /// NR_046361 /// XM_005250966 /// XM_006716582 /// XM_006716583 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 217535_at AV720514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV720514 /FEA=EST /DB_XREF=gi:10817666 /DB_XREF=est:AV720514 /CLONE=GLCGSB09 /UG=Hs.282721 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AV720514 217536_x_at M78162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M78162 /FEA=EST /DB_XREF=gi:273899 /DB_XREF=est:EST01755 /CLONE=HHCPN60 /UG=Hs.314534 ESTs, Moderately similar to ALU5_HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens M78162 217537_x_at M78162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M78162 /FEA=EST /DB_XREF=gi:273899 /DB_XREF=est:EST01755 /CLONE=HHCPN60 /UG=Hs.314534 ESTs, Moderately similar to ALU5_HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens M78162 217538_at BF347113 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF347113 /FEA=EST /DB_XREF=gi:11294708 /DB_XREF=est:602020879F1 /CLONE=IMAGE:4156602 /UG=Hs.273138 ESTs BF347113 small G protein signaling modulator 2 SGSM2 9905 NM_001098509 /// NM_014853 /// XM_006721613 /// XM_006721614 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 217539_at W28849 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W28849 /FEA=EST /DB_XREF=gi:1308815 /DB_XREF=est:52g6 /UG=Hs.33862 ESTs W28849 chromosome 18 open reading frame 25 C18orf25 147339 NM_001008239 /// NM_145055 0008152 // metabolic process // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 217540_at AA721025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA721025 /FEA=EST /DB_XREF=gi:2737160 /DB_XREF=est:nx89g05.s1 /CLONE=IMAGE:1269464 /UG=Hs.293253 ESTs AA721025 neurexophilin and PC-esterase domain family, member 3 NXPE3 91775 NM_001134456 /// NM_145037 0005576 // extracellular region // inferred from electronic annotation 217541_x_at BG290532 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG290532 /FEA=EST /DB_XREF=gi:13047560 /DB_XREF=est:602388395F1 /CLONE=IMAGE:4517206 /UG=Hs.11210 ESTs, Moderately similar to Z137_HUMAN ZINC FINGER PROTEIN 13 H.sapiens BG290532 zinc finger protein 816 /// ZNF816-ZNF321P readthrough ZNF816 /// ZNF816-ZNF321P 125893 /// 100529240 NM_001031665 /// NM_001202456 /// NM_001202457 /// NM_001202473 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 217542_at BE930512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE930512 /FEA=EST /DB_XREF=gi:10456588 /DB_XREF=est:RC6-GN0071-160800-021-D01 /UG=Hs.168732 ESTs BE930512 MDM2 proto-oncogene, E3 ubiquitin protein ligase MDM2 4193 NM_001145336 /// NM_001145337 /// NM_001145339 /// NM_001145340 /// NM_001278462 /// NM_002392 /// NM_006878 /// NM_006879 /// NM_006880 /// NM_006881 /// NM_006882 /// NM_032739 /// XM_005268872 /// XM_006719399 /// XM_006719400 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018205 // peptidyl-lysine modification // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from direct assay /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045184 // establishment of protein localization // inferred from direct assay /// 0045472 // response to ether // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071301 // cellular response to vitamin B1 // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071494 // cellular response to UV-C // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016604 // nuclear body // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 217543_s_at BE890314 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE890314 /FEA=EST /DB_XREF=gi:10348509 /DB_XREF=est:601431767F1 /CLONE=IMAGE:3916816 /UG=Hs.314499 ESTs, Moderately similar to T43492 hypothetical protein DKFZp434A219.1 H.sapiens BE890314 membrane-bound transcription factor peptidase, site 1 MBTPS1 8720 NM_003791 /// NM_201268 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // not recorded /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // not recorded /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217544_at AA768909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA768909 /FEA=EST /DB_XREF=gi:2820147 /DB_XREF=est:nz82h01.s1 /CLONE=IMAGE:1302001 /UG=Hs.293205 ESTs, Weakly similar to BC39498 1 H.sapiens AA768909 microRNA 3916 MIR3916 100500849 NR_037480 217545_at AW081820 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW081820 /FEA=EST /DB_XREF=gi:6036972 /DB_XREF=est:xb55d12.x1 /CLONE=IMAGE:2580215 /UG=Hs.287317 ESTs, Weakly similar to A59252 myosin heavy chain, nonmuscle, form IIB H.sapiens AW081820 myosin, heavy chain 14, non-muscle MYH14 79784 NM_001077186 /// NM_001145809 /// NM_024729 /// XM_006723386 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from mutant phenotype /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 217546_at R06655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R06655 /FEA=EST /DB_XREF=gi:757275 /DB_XREF=est:yf10e02.r1 /CLONE=IMAGE:126458 /UG=Hs.188518 ESTs, Moderately similar to AF078844 1 hqp0376 protein H.sapiens R06655 metallothionein 1M MT1M 4499 NM_176870 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 217547_x_at BF308250 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF308250 /FEA=EST /DB_XREF=gi:11255432 /DB_XREF=est:601890308F1 /CLONE=IMAGE:4131673 /UG=Hs.315103 ESTs, Moderately similar to DNA-binding protein H.sapiens BF308250 zinc finger protein 675 ZNF675 171392 NM_138330 /// XM_005259800 /// XM_005259801 /// XM_006722679 /// XM_006722680 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0043508 // negative regulation of JUN kinase activity // inferred from direct assay /// 0045453 // bone resorption // traceable author statement /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 2000660 // negative regulation of interleukin-1-mediated signaling pathway // inferred from direct assay /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217548_at AA491625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA491625 /FEA=EST /DB_XREF=gi:2221187 /DB_XREF=est:ne80d01.s1 /CLONE=IMAGE:910561 /UG=Hs.293940 ESTs AA491625 actin-related protein 2/3 complex inhibitor ARPIN 348110 NM_001282380 /// NM_182616 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 217549_at AW574933 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW574933 /FEA=EST /DB_XREF=gi:7246472 /DB_XREF=est:UI-HF-BL0-abq-b-09-0-UI.s1 /CLONE=IMAGE:3057353 /UG=Hs.248844 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW574933 NCK-associated protein 1-like NCKAP1L 3071 NM_001184976 /// NM_005337 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0002262 // myeloid cell homeostasis // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035509 // negative regulation of myosin-light-chain-phosphatase activity // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from mutant phenotype /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043372 // positive regulation of CD4-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0043378 // positive regulation of CD8-positive, alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0045579 // positive regulation of B cell differentiation // inferred from sequence or structural similarity /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from sequence or structural similarity /// 0045621 // positive regulation of lymphocyte differentiation // inferred from sequence or structural similarity /// 0045648 // positive regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from expression pattern /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from sequence or structural similarity /// 0070358 // actin polymerization-dependent cell motility // inferred from mutant phenotype /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from mutant phenotype /// 0030675 // Rac GTPase activator activity // inferred from mutant phenotype /// 0032403 // protein complex binding // inferred from direct assay 217550_at AA576497 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA576497 /FEA=EST /DB_XREF=gi:2353997 /DB_XREF=est:nm76b07.s1 /CLONE=IMAGE:1074133 /UG=Hs.252497 ESTs AA576497 activating transcription factor 6 ATF6 22926 NM_007348 /// XM_006711224 /// XM_006711225 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006990 // positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217551_at AA719797 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA719797 /FEA=EST /DB_XREF=gi:2732896 /DB_XREF=est:zg54c07.s1 /CLONE=IMAGE:397164 /UG=Hs.194362 olfactory receptor, family 7, subfamily E, member 13 pseudogene AA719797 olfactory receptor, family 7, subfamily E, member 14 pseudogene OR7E14P 10819 NR_045002 0016021 // integral component of membrane // inferred from electronic annotation 217552_x_at AI432713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI432713 /FEA=EST /DB_XREF=gi:4283899 /DB_XREF=est:th43e02.x1 /CLONE=IMAGE:2121050 /UG=Hs.241053 ESTs AI432713 complement component (3b/4b) receptor 1 (Knops blood group) CR1 1378 NM_000573 /// NM_000651 /// XM_005273064 /// XM_006711166 /// XM_006711167 /// XM_006711168 0002376 // immune system process // inferred from electronic annotation /// 0002430 // complement receptor mediated signaling pathway // inferred from direct assay /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045957 // negative regulation of complement activation, alternative pathway // inferred from direct assay /// 0045959 // negative regulation of complement activation, classical pathway // inferred from direct assay /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900005 // positive regulation of serine-type endopeptidase activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001851 // complement component C3b binding // inferred from direct assay /// 0001855 // complement component C4b binding // inferred from direct assay /// 0001861 // complement component C4b receptor activity // inferred from direct assay /// 0004877 // complement component C3b receptor activity // inferred from direct assay 217553_at AW129021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW129021 /FEA=EST /DB_XREF=gi:6116965 /DB_XREF=est:xe93h03.x1 /CLONE=IMAGE:2615477 /UG=Hs.243537 ESTs, Highly similar to AC005061 1 similar to AAC79150 H.sapiens AW129021 STEAP family member 1B STEAP1B 256227 NM_001164460 /// NM_207342 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217554_at AV719355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV719355 /FEA=EST /DB_XREF=gi:10816507 /DB_XREF=est:AV719355 /CLONE=GLCEMB06 /UG=Hs.97109 ESTs AV719355 217555_at AI042030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI042030 /FEA=EST /DB_XREF=gi:3281224 /DB_XREF=est:ox60a09.x1 /CLONE=IMAGE:1660696 /UG=Hs.132153 ESTs AI042030 structural maintenance of chromosomes 1A SMC1A 8243 NM_001281463 /// NM_006306 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007064 // mitotic sister chromatid cohesion // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0009314 // response to radiation // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from electronic annotation /// 0008280 // cohesin core heterodimer // traceable author statement /// 0030893 // meiotic cohesin complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 217556_at W26966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W26966 /FEA=EST /DB_XREF=gi:1306194 /DB_XREF=est:16h5 /UG=Hs.293838 ESTs W26966 chloride channel, voltage-sensitive 4 CLCN4 1183 NM_001256944 /// NM_001830 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 217557_s_at AV710357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV710357 /FEA=EST /DB_XREF=gi:10728986 /DB_XREF=est:AV710357 /CLONE=CuAAFE05 /UG=Hs.267158 ESTs AV710357 carboxypeptidase M CPM 1368 NM_001005502 /// NM_001874 /// NM_198320 /// XM_005268653 0006508 // proteolysis // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 217558_at BE971373 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE971373 /FEA=EST /DB_XREF=gi:10584709 /DB_XREF=est:601651546F1 /CLONE=IMAGE:3934979 /UG=Hs.282639 ESTs, Moderately similar to 1506290A cytochrome P450 H.sapiens BE971373 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 217559_at AI001784 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI001784 /FEA=EST /DB_XREF=gi:3202255 /DB_XREF=est:ot41g06.s1 /CLONE=IMAGE:1619386 /UG=Hs.308332 ESTs, Highly similar to A42735 ribosomal protein L10, cytosolic H.sapiens AI001784 ribosomal protein L10-like RPL10L 140801 NM_080746 0006412 // translation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 217560_at AI879383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI879383 /FEA=EST /DB_XREF=gi:5553432 /DB_XREF=est:au50b05.x1 /CLONE=IMAGE:2518161 /UG=Hs.190885 ESTs, Moderately similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI879383 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 GGA1 26088 NM_001001560 /// NM_001001561 /// NM_001172687 /// NM_001172688 /// NM_013365 /// XM_005261517 /// XM_005261518 /// XM_005261520 /// XM_005261522 /// XM_006724228 /// XM_006724229 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217561_at BF447272 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF447272 /FEA=EST /DB_XREF=gi:11512410 /DB_XREF=est:7p47a12.x1 /CLONE=IMAGE:3648695 /UG=Hs.288190 ESTs BF447272 calcitonin-related polypeptide alpha CALCA 796 NM_001033952 /// NM_001033953 /// NM_001741 /// XM_005253134 0001935 // endothelial cell proliferation // inferred from direct assay /// 0001944 // vasculature development // inferred from direct assay /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from direct assay /// 0001984 // vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031623 // receptor internalization // inferred from direct assay /// 0031645 // negative regulation of neurological system process // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032730 // positive regulation of interleukin-1 alpha production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from direct assay /// 0045651 // positive regulation of macrophage differentiation // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045762 // positive regulation of adenylate cyclase activity // inferred from direct assay /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0045986 // negative regulation of smooth muscle contraction // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031716 // calcitonin receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 217562_at BF589529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF589529 /FEA=EST /DB_XREF=gi:11681865 /DB_XREF=est:naa05f05.x1 /CLONE=IMAGE:3254144 /UG=Hs.106642 ESTs, Weakly similar to hypothetical protein H.sapiens BF589529 bone morphogenetic protein/retinoic acid inducible neural-specific 3 BRINP3 339479 NM_199051 /// XM_005245117 /// XM_005245118 /// XM_005245119 /// XM_005245120 /// XM_005245123 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 217563_at AW238724 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW238724 /FEA=EST /DB_XREF=gi:6571113 /DB_XREF=est:xp30h08.x1 /CLONE=IMAGE:2741919 /UG=Hs.314230 ESTs, Highly similar to clock H.sapiens AW238724 clock circadian regulator CLOCK 9575 NM_001267843 /// NM_004898 /// XM_005265787 /// XM_006714054 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // traceable author statement /// 0009648 // photoperiodism // traceable author statement /// 0016573 // histone acetylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from mutant phenotype /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 2000074 // regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0004402 // histone acetyltransferase activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 217564_s_at W80357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W80357 /FEA=EST /DB_XREF=gi:1391394 /DB_XREF=est:zh49a06.s1 /CLONE=IMAGE:415378 /UG=Hs.326685 Homo sapiens carbamoyl-phosphate synthetase 1, mitochondrial (CPS1), mRNA W80357 carbamoyl-phosphate synthase 1, mitochondrial CPS1 1373 NM_001122633 /// NM_001122634 /// NM_001875 0000050 // urea cycle // non-traceable author statement /// 0000050 // urea cycle // traceable author statement /// 0001101 // response to acid // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0005980 // glycogen catabolic process // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007494 // midgut development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0019240 // citrulline biosynthetic process // non-traceable author statement /// 0019433 // triglyceride catabolic process // inferred from mutant phenotype /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from mutant phenotype /// 0046209 // nitric oxide metabolic process // inferred from mutant phenotype /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055081 // anion homeostasis // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0070409 // carbamoyl phosphate biosynthetic process // inferred from mutant phenotype /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation /// 0071400 // cellular response to oleic acid // inferred from electronic annotation /// 0071548 // response to dexamethasone // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004087 // carbamoyl-phosphate synthase (ammonia) activity // inferred from mutant phenotype /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 217565_at BF110551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110551 /FEA=EST /DB_XREF=gi:10940241 /DB_XREF=est:7n38h09.x1 /CLONE=IMAGE:3567208 /UG=Hs.253600 ESTs, Highly similar to S50128 glutamate receptor 3 isoform flip H.sapiens BF110551 glutamate receptor, ionotropic, AMPA 3 GRIA3 2892 NM_000828 /// NM_001256743 /// NM_007325 /// NM_181894 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from direct assay /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // not recorded 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // not recorded /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004971 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded 217566_s_at BF222018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222018 /FEA=EST /DB_XREF=gi:11129195 /DB_XREF=est:7p41a04.x1 /CLONE=IMAGE:3648271 /UG=Hs.289803 ESTs, Moderately similar to S71105 protein-glutamine gamma-glutamyltransferase H.sapiens BF222018 transglutaminase 4 TGM4 7047 NM_003241 /// XM_005265419 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018184 // protein polyamination // non-traceable author statement /// 0042628 // mating plug formation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217567_at BF222018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222018 /FEA=EST /DB_XREF=gi:11129195 /DB_XREF=est:7p41a04.x1 /CLONE=IMAGE:3648271 /UG=Hs.289803 ESTs, Moderately similar to S71105 protein-glutamine gamma-glutamyltransferase H.sapiens BF222018 transglutaminase 4 TGM4 7047 NM_003241 /// XM_005265419 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018184 // protein polyamination // non-traceable author statement /// 0042628 // mating plug formation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003810 // protein-glutamine gamma-glutamyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217568_at AI696737 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI696737 /FEA=EST /DB_XREF=gi:4984637 /DB_XREF=est:wc56f02.x1 /CLONE=IMAGE:2322651 /UG=Hs.304757 Homo sapiens similar to human epididymis-specific 3 alpha (H. sapiens) (LOC65721), mRNA AI696737 epididymal protein 3A EDDM3A 10876 NM_006683 0007321 // sperm displacement // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 217569_x_at AA017093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA017093 /FEA=EST /DB_XREF=gi:1479257 /DB_XREF=est:ze37h10.s1 /CLONE=IMAGE:361219 /UG=Hs.271780 ESTs AA017093 217570_x_at AV718487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV718487 /FEA=EST /DB_XREF=gi:10815639 /DB_XREF=est:AV718487 /CLONE=GLCFVH09 /UG=Hs.282656 ESTs AV718487 217571_at AV661138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV661138 /FEA=EST /DB_XREF=gi:9882152 /DB_XREF=est:AV661138 /CLONE=GLCGPA11 /UG=Hs.282712 ESTs AV661138 217572_at AA654586 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA654586 /FEA=EST /DB_XREF=gi:2590740 /DB_XREF=est:nt04f11.s1 /CLONE=IMAGE:1192173 /UG=Hs.325505 ESTs, Moderately similar to HBA_HUMAN HEMOGLOBIN ALPHA CHAI H.sapiens AA654586 217573_at AW138468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW138468 /FEA=EST /DB_XREF=gi:6142786 /DB_XREF=est:UI-H-BI1-adg-f-01-0-UI.s1 /CLONE=IMAGE:2716920 /UG=Hs.299882 ESTs, Highly similar to N-methyl-D-aspartate receptor 2C subunit precursor H.sapiens AW138468 glutamate receptor, ionotropic, N-methyl D-aspartate 2C GRIN2C 2905 NM_000835 /// NM_001278553 /// NR_103735 /// XM_006721845 /// XM_006721846 /// XM_006721847 /// XM_006721848 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0033058 // directional locomotion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // not recorded /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // inferred from electronic annotation /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 217574_at T65123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T65123 /FEA=EST /DB_XREF=gi:674168 /DB_XREF=est:yc74c07.s1 /CLONE=IMAGE:21659 /UG=Hs.298050 ESTs, Moderately similar to CAD8_HUMAN CADHERIN-8 PRECURSOR H.sapiens T65123 cadherin 8, type 2 CDH8 1006 NM_001796 /// XM_005255759 /// XM_005255760 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043083 // synaptic cleft // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217575_s_at BF692958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF692958 /FEA=EST /DB_XREF=gi:11978366 /DB_XREF=est:602080393F1 /CLONE=IMAGE:4244831 /UG=Hs.333042 Homo sapiens similar to son of sevenless (Drosophila) homolog 1 (H. sapiens) (LOC63378), mRNA BF692958 son of sevenless homolog 2 (Drosophila) SOS2 6655 NM_006939 /// XM_005268021 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217576_x_at BF692958 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF692958 /FEA=EST /DB_XREF=gi:11978366 /DB_XREF=est:602080393F1 /CLONE=IMAGE:4244831 /UG=Hs.333042 Homo sapiens similar to son of sevenless (Drosophila) homolog 1 (H. sapiens) (LOC63378), mRNA BF692958 son of sevenless homolog 2 (Drosophila) SOS2 6655 NM_006939 /// XM_005268021 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217577_at AW576871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW576871 /FEA=EST /DB_XREF=gi:7251920 /DB_XREF=est:RC2-BT0318-110100-012-e02 /UG=Hs.201420 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW576871 217578_at AI679024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI679024 /FEA=EST /DB_XREF=gi:4889206 /DB_XREF=est:tu71a10.x1 /CLONE=IMAGE:2256474 /UG=Hs.201420 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI679024 217579_x_at AW301806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301806 /FEA=EST /DB_XREF=gi:6711483 /DB_XREF=est:xr56e11.x1 /CLONE=IMAGE:2764172 /UG=Hs.150551 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW301806 217580_x_at AW301806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301806 /FEA=EST /DB_XREF=gi:6711483 /DB_XREF=est:xr56e11.x1 /CLONE=IMAGE:2764172 /UG=Hs.150551 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW301806 217581_at AA741028 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA741028 /FEA=EST /DB_XREF=gi:2779620 /DB_XREF=est:ny99c07.s1 /CLONE=IMAGE:1286412 /UG=Hs.256155 ESTs, Moderately similar to ALUA_HUMAN !!!! ALU CLASS A WARNING ENTRY !!! H.sapiens AA741028 217582_at AA018777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA018777 /FEA=EST /DB_XREF=gi:1481298 /DB_XREF=est:ze51b01.r1 /CLONE=IMAGE:362473 /UG=Hs.271784 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA018777 217583_at BG433489 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG433489 /FEA=EST /DB_XREF=gi:13339995 /DB_XREF=est:602497919F1 /CLONE=IMAGE:4611460 /UG=Hs.297257 ESTs BG433489 uncharacterized LOC101929036 /// phenylalanine hydroxylase LOC101929036 /// PAH 5053 /// 101929036 NM_000277 /// XR_246028 /// XR_253108 /// XR_424391 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // non-traceable author statement /// 0042423 // catecholamine biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004505 // phenylalanine 4-monooxygenase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016714 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217584_at U55987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U55987 /FEA=EST /DB_XREF=gi:1354543 /DB_XREF=est:HSU55987 /CLONE=47507 /UG=Hs.323773 ESTs, Highly similar to NPC1_HUMAN NIEMANN-PICK C1 PROTEIN PRECURSOR H.sapiens U55987 Niemann-Pick disease, type C1 NPC1 4864 NM_000271 /// XM_005258277 /// XM_005258278 /// XM_005258279 /// XM_006722479 0006486 // protein glycosylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0007041 // lysosomal transport // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from sequence or structural similarity /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from direct assay /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071404 // cellular response to low-density lipoprotein particle stimulus // inferred from electronic annotation /// 0090150 // establishment of protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0015248 // sterol transporter activity // traceable author statement /// 0015485 // cholesterol binding // inferred from direct assay 217585_at BE502910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE502910 /FEA=EST /DB_XREF=gi:9705318 /DB_XREF=est:hz81a09.x1 /CLONE=IMAGE:3214360 /UG=Hs.166449 ESTs, Weakly similar to S55024 nebulin, skeletal muscle H.sapiens BE502910 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 217586_x_at N35922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N35922 /FEA=EST /DB_XREF=gi:1157064 /DB_XREF=est:yy28g05.s1 /CLONE=IMAGE:272600 /UG=Hs.269852 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens N35922 217587_at AI274196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI274196 /FEA=EST /DB_XREF=gi:3896464 /DB_XREF=est:ql46b12.x1 /CLONE=IMAGE:1875359 /UG=Hs.292368 ESTs AI274196 217588_at AW971983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971983 /FEA=EST /DB_XREF=gi:8161949 /DB_XREF=est:EST384192 /UG=Hs.293003 ESTs, Moderately similar to ALU4_HUMAN ALU SUBFAMILY SB2 SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW971983 cation channel, sperm associated 2 /// cation channel, sperm associated 2 pseudogene 1 /// uncharacterized LOC101930343 CATSPER2 /// CATSPER2P1 /// LOC101930343 117155 /// 440278 /// 101930343 NM_001282309 /// NM_001282310 /// NM_054020 /// NM_172095 /// NM_172097 /// NR_002318 /// NR_110319 /// XR_250568 /// XR_429522 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030317 // sperm motility // not recorded /// 0032504 // multicellular organism reproduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035036 // sperm-egg recognition // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036128 // CatSper complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005227 // calcium activated cation channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217589_at AW300309 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW300309 /FEA=EST /DB_XREF=gi:6709909 /DB_XREF=est:xs59e08.x1 /CLONE=IMAGE:2773958 /UG=Hs.27453 ESTs, Moderately similar to G01251 Rar protein H.sapiens AW300309 RAB40A, member RAS oncogene family RAB40A 142684 NM_080879 /// XM_005262083 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 217590_s_at AA502609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA502609 /FEA=EST /DB_XREF=gi:2237576 /DB_XREF=est:ne42a02.s1 /CLONE=IMAGE:899978 /UG=Hs.326646 Homo sapiens ankyrin-like with transmembrane domains 1 (ANKTM1), mRNA AA502609 transient receptor potential cation channel, subfamily A, member 1 TRPA1 8989 NM_007332 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050955 // thermoception // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050968 // detection of chemical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015267 // channel activity // traceable author statement 217591_at BF725121 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF725121 /FEA=EST /DB_XREF=gi:12041032 /DB_XREF=est:bx12e01.x1 /CLONE=bx12e01 /UG=Hs.272108 ESTs BF725121 SKI-like proto-oncogene SKIL 6498 NM_001145097 /// NM_001145098 /// NM_001248008 /// NM_005414 /// XM_005247721 /// XM_006713735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from sequence or structural similarity /// 0046677 // response to antibiotic // inferred from expression pattern /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from mutant phenotype /// 0070207 // protein homotrimerization // inferred from direct assay /// 0070208 // protein heterotrimerization // inferred from direct assay /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902231 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction 217592_at AV684859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV684859 /FEA=EST /DB_XREF=gi:10286722 /DB_XREF=est:AV684859 /CLONE=GKCDJA03 /UG=Hs.251334 ESTs, Moderately similar to ALU6_HUMAN ALU SUBFAMILY SP SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AV684859 zinc finger, SWIM-type containing 1 ZSWIM1 90204 NM_080603 /// XM_005260610 /// XM_005260611 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 217593_at AI375002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375002 /FEA=EST /DB_XREF=gi:4174992 /DB_XREF=est:ta54b11.x1 /CLONE=IMAGE:2047869 /UG=Hs.272014 ESTs, Weakly similar to ALU3_HUMAN ALU SUBFAMILY SB1 SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI375002 zinc finger and SCAN domain containing 18 ZSCAN18 65982 NM_001145542 /// NM_001145543 /// NM_001145544 /// NM_023926 /// NR_027135 /// XM_005259174 /// XM_006723335 /// XM_006723336 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217594_at R25849 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R25849 /FEA=EST /DB_XREF=gi:781984 /DB_XREF=est:yh42a11.r1 /CLONE=IMAGE:132380 /UG=Hs.217305 ESTs R25849 zinc finger, CCHC domain containing 11 ZCCHC11 23318 NM_001009881 /// NM_001009882 /// NM_015269 /// XM_005270676 /// XM_005270678 /// XM_005270679 /// XM_005270680 /// XM_005270681 /// XM_005270682 /// XM_005270683 /// XM_005270684 /// XM_005270685 /// XM_006710498 /// XM_006710499 /// XM_006710500 0001816 // cytokine production // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010586 // miRNA metabolic process // inferred from sequence or structural similarity /// 0010587 // miRNA catabolic process // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from mutant phenotype /// 0031123 // RNA 3'-end processing // inferred from direct assay /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0070102 // interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050265 // RNA uridylyltransferase activity // inferred from direct assay 217595_at AV701723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV701723 /FEA=EST /DB_XREF=gi:10718053 /DB_XREF=est:AV701723 /CLONE=ADBCTC02 /UG=Hs.237849 ESTs AV701723 G1 to S phase transition 1 GSPT1 2935 NM_001130006 /// NM_001130007 /// NM_002094 /// XM_005255274 /// XM_005255275 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from mutant phenotype /// 0006479 // protein methylation // inferred from direct assay 0005622 // intracellular // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003747 // translation release factor activity // inferred from mutant phenotype /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217596_at AA649851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA649851 /FEA=EST /DB_XREF=gi:2577179 /DB_XREF=est:ns53g06.s1 /CLONE=IMAGE:1187386 /UG=Hs.326457 ESTs AA649851 UPF3 regulator of nonsense transcripts homolog A (yeast) UPF3A 65110 NM_023011 /// NM_080687 /// XM_005266200 /// XM_005266201 /// XM_005266202 /// XM_006719991 /// XR_429283 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0035145 // exon-exon junction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217597_x_at AI344141 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI344141 /FEA=EST /DB_XREF=gi:4081347 /DB_XREF=est:tc02d09.x1 /CLONE=IMAGE:2062673 /UG=Hs.229850 ESTs, Highly similar to G01251 Rar protein H.sapiens AI344141 RAB40B, member RAS oncogene family RAB40B 10966 NM_006822 /// XM_005256334 /// XM_005256335 /// XM_006722271 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 217598_at BG236351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG236351 /FEA=EST /DB_XREF=gi:12750198 /DB_XREF=est:naf26f12.x1 /CLONE=IMAGE:4142350 /UG=Hs.148161 ESTs BG236351 cyclin-dependent kinase 2 interacting protein CINP 51550 NM_001177611 /// NM_001177612 /// NM_032630 /// XM_005267753 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217599_s_at BE910600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE910600 /FEA=EST /DB_XREF=gi:10407359 /DB_XREF=est:601501171F1 /CLONE=IMAGE:3903161 /UG=Hs.288751 ESTs, Highly similar to HIC protein isoform p40 H.sapiens BE910600 MyoD family inhibitor domain containing MDFIC 29969 NM_001166345 /// NM_001166346 /// NM_199072 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050434 // positive regulation of viral transcription // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0072588 // box H/ACA RNP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from direct assay 217600_at BF511678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511678 /FEA=EST /DB_XREF=gi:11594976 /DB_XREF=est:UI-H-BI4-aom-c-02-0-UI.s1 /CLONE=IMAGE:3085418 /UG=Hs.128311 ESTs BF511678 signal peptide, CUB domain, EGF-like 3 SCUBE3 222663 NM_152753 /// XM_005248943 /// XM_005248946 /// XM_005248947 /// XM_005248948 0051260 // protein homooligomerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from physical interaction 0005576 // extracellular region // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217601_at AL523184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523184 /FEA=EST /DB_XREF=gi:12786677 /DB_XREF=est:AL523184 /CLONE=CS0DC001YI02 (5 prime) /UG=Hs.288146 ESTs, Highly similar to KIAA0169 protein H.sapiens AL523184 nucleoporin 188kDa NUP188 23511 NM_015354 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation 217602_at AI191118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI191118 /FEA=EST /DB_XREF=gi:3742327 /DB_XREF=est:qe18c05.x1 /CLONE=IMAGE:1739336 /UG=Hs.222015 ESTs AI191118 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 217603_at AW444520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW444520 /FEA=EST /DB_XREF=gi:6986282 /DB_XREF=est:UI-H-BI3-akb-h-11-0-UI.s1 /CLONE=IMAGE:2733933 /UG=Hs.256986 ESTs, Moderately similar to VPP2_HUMAN VACUOLAR PROTON TRANSLOCATING ATPASE 116 KDA SUBUNIT A ISOFORM 2 H.sapiens AW444520 ATPase, H+ transporting, lysosomal V0 subunit a2 ATP6V0A2 23545 NM_012463 /// XM_005253563 /// XM_006719317 /// XM_006719318 /// XR_429088 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 217604_at AI086530 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI086530 /FEA=EST /DB_XREF=gi:3424953 /DB_XREF=est:oz72a04.x1 /CLONE=IMAGE:1680846 /UG=Hs.255883 ESTs AI086530 217605_at AW851066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW851066 /FEA=EST /DB_XREF=gi:7946583 /DB_XREF=est:IL3-CT0220-150200-070-B02 /UG=Hs.314334 ESTs AW851066 ubiquitin specific peptidase 27, X-linked USP27X 389856 NM_001145073 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 217606_at AI653960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI653960 /FEA=EST /DB_XREF=gi:4737939 /DB_XREF=est:ty03h10.x1 /CLONE=IMAGE:2278051 /UG=Hs.196555 ESTs AI653960 217607_x_at AA733172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA733172 /FEA=EST /DB_XREF=gi:2754531 /DB_XREF=est:zg77h02.s1 /CLONE=IMAGE:399411 /UG=Hs.150904 ESTs AA733172 eukaryotic translation initiation factor 4 gamma, 2 EIF4G2 1982 NM_001042559 /// NM_001172705 /// NM_001418 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0008219 // cell death // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 217608_at AW408767 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW408767 /FEA=EST /DB_XREF=gi:6927824 /DB_XREF=est:UI-HF-BM0-adw-h-10-0-UI.r1 /CLONE=IMAGE:3063402 /UG=Hs.293381 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW408767 SREK1-interacting protein 1 SREK1IP1 285672 NM_173829 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217609_at BG420747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG420747 /FEA=EST /DB_XREF=gi:13327253 /DB_XREF=est:602448537F1 /CLONE=IMAGE:4586984 /UG=Hs.259677 ESTs, Weakly similar to S23753 ribosomal protein L13, cytosolic H.sapiens BG420747 leucine rich repeat containing 23 /// ribosomal protein L13 pseudogene 5 LRRC23 /// RPL13P5 10233 /// 283345 NM_001135217 /// NM_006992 /// NM_201650 /// NR_002803 0005515 // protein binding // inferred from electronic annotation 217610_at AL047879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL047879 /FEA=EST /DB_XREF=gi:4728067 /DB_XREF=est:DKFZp586N1222_s1 /CLONE=DKFZp586N1222 /UG=Hs.194251 ESTs, Weakly similar to ALU2_HUMAN ALU SUBFAMILY SB SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AL047879 speedy/RINGO cell cycle regulator family member E2 SPDYE2 441273 NM_001031618 /// XM_006715997 /// XM_006715998 217611_at W28800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W28800 /FEA=EST /DB_XREF=gi:1308811 /DB_XREF=est:52g12 /UG=Hs.169802 ESTs W28800 glutamate-rich 1 ERICH1 157697 NM_207332 /// XM_005266020 /// XM_006716234 /// XM_006716235 217612_at BE378994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE378994 /FEA=EST /DB_XREF=gi:9324359 /DB_XREF=est:601236247F1 /CLONE=IMAGE:3608626 /UG=Hs.271717 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens BE378994 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) TIMM50 92609 NM_001001563 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007006 // mitochondrial membrane organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from physical interaction /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005134 // interleukin-2 receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 217613_at AW173720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW173720 /FEA=EST /DB_XREF=gi:6439668 /DB_XREF=est:xj11f05.x1 /CLONE=IMAGE:2656929 /UG=Hs.271356 ESTs AW173720 transmembrane protein 144 TMEM144 55314 NM_018342 /// XM_005263110 /// XM_005263112 /// XM_006714254 /// XM_006714255 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217614_at AI439416 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI439416 /FEA=EST /DB_XREF=gi:4304169 /DB_XREF=est:tj04b04.x1 /CLONE=IMAGE:2140495 /UG=Hs.165728 ESTs AI439416 histocompatibility (minor) HA-1 HMHA1 23526 NM_001258328 /// NM_001282334 /// NM_001282335 /// NM_012292 /// XM_006722713 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217615_at BF448531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448531 /FEA=EST /DB_XREF=gi:11514556 /DB_XREF=est:7n72e02.x1 /CLONE=IMAGE:3570146 /UG=Hs.248979 ESTs, Moderately similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens BF448531 217616_at AV763520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV763520 /FEA=EST /DB_XREF=gi:10921368 /DB_XREF=est:AV763520 /CLONE=MDSCIH03 /UG=Hs.282113 ESTs AV763520 217617_at AW451711 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451711 /FEA=EST /DB_XREF=gi:6992487 /DB_XREF=est:UI-H-BI3-ale-c-02-0-UI.s1 /CLONE=IMAGE:2736386 /UG=Hs.313760 ESTs AW451711 217618_x_at AW007988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007988 /FEA=EST /DB_XREF=gi:5856766 /DB_XREF=est:wv48a04.x1 /CLONE=IMAGE:2532750 /UG=Hs.233299 ESTs AW007988 HUS1 checkpoint homolog (S. pombe) HUS1 3364 NM_004507 /// NR_037917 /// XR_428079 /// XR_428080 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217619_x_at AW474615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW474615 /FEA=EST /DB_XREF=gi:7044721 /DB_XREF=est:xy18c02.x1 /CLONE=IMAGE:2853506 /UG=Hs.250988 ESTs AW474615 217620_s_at AA805318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA805318 /FEA=EST /DB_XREF=gi:2874068 /DB_XREF=est:oc15b01.s1 /CLONE=IMAGE:1340905 /UG=Hs.181033 ESTs, Moderately similar to A54600 1-phosphatidylinositol 3-kinase H.sapiens AA805318 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta PIK3CB 5291 NM_001256045 /// NM_006219 /// XM_005247530 /// XM_005247531 /// XM_005247532 /// XM_006713659 0000187 // activation of MAPK activity // traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010508 // positive regulation of autophagy // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0070527 // platelet aggregation // traceable author statement /// 2000369 // regulation of clathrin-mediated endocytosis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded 217621_at AI399889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI399889 /FEA=EST /DB_XREF=gi:4242976 /DB_XREF=est:tg69a09.x1 /CLONE=IMAGE:2114008 /UG=Hs.14468 ESTs AI399889 solute carrier family 6 (neurotransmitter transporter), member 2 SLC6A2 6530 NM_001043 /// NM_001172501 /// NM_001172502 /// NM_001172504 /// XM_006721263 0006810 // transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015844 // monoamine transport // inferred from direct assay /// 0015874 // norepinephrine transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0005333 // norepinephrine transmembrane transporter activity // inferred from electronic annotation /// 0005334 // norepinephrine:sodium symporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008504 // monoamine transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 217622_at AA018187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA018187 /FEA=EST /DB_XREF=gi:1481460 /DB_XREF=est:ze53d02.s1 /CLONE=IMAGE:362691 /UG=Hs.313951 ESTs AA018187 rhomboid domain containing 3 RHBDD3 25807 NM_012265 /// XM_005261504 /// XM_006724224 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation 217623_at BF114815 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF114815 /FEA=EST /DB_XREF=gi:10984291 /DB_XREF=est:7j67g06.x1 /CLONE=IMAGE:3391546 /UG=Hs.130465 ESTs BF114815 myosin light chain kinase 3 MYLK3 91807 NM_182493 /// XM_005256233 /// XM_005256234 /// XM_005256235 /// XM_006721333 /// XM_006721334 0002528 // regulation of vascular permeability involved in acute inflammatory response // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from sequence or structural similarity /// 0048769 // sarcomerogenesis // inferred from sequence or structural similarity /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060298 // positive regulation of sarcomere organization // inferred from sequence or structural similarity /// 0071347 // cellular response to interleukin-1 // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004687 // myosin light chain kinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 217624_at AA464753 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA464753 /FEA=EST /DB_XREF=gi:2189637 /DB_XREF=est:zx86c10.s1 /CLONE=IMAGE:810642 /UG=Hs.193324 ESTs AA464753 PDGFA associated protein 1 PDAP1 11333 NM_014891 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 217625_x_at AA102667 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA102667 /FEA=EST /DB_XREF=gi:1647984 /DB_XREF=est:zn73e05.s1 /CLONE=IMAGE:563840 /UG=Hs.264673 ESTs, Weakly similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA102667 long intergenic non-protein coding RNA 963 LINC00963 100506190 NR_038955 217626_at BF508244 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508244 /FEA=EST /DB_XREF=gi:11591542 /DB_XREF=est:UI-H-BI4-aqa-b-02-0-UI.s1 /CLONE=IMAGE:3089210 /UG=Hs.300832 ESTs, Highly similar to I53872 dihydrodiol dehydrogenase H.sapiens BF508244 aldo-keto reductase family 1, member C1 AKR1C1 1645 NM_001353 0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation 217627_at BE515346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE515346 /FEA=EST /DB_XREF=gi:9722561 /DB_XREF=est:601235986F1 /CLONE=IMAGE:3608205 /UG=Hs.278871 ESTs, Weakly similar to S47072 finger protein HZF10, Krueppel-related H.sapiens BE515346 zinc finger protein 573 ZNF573 126231 NM_001172689 /// NM_001172690 /// NM_001172691 /// NM_001172692 /// NM_152360 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 217628_at BF032808 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF032808 /FEA=EST /DB_XREF=gi:10740520 /DB_XREF=est:601455629F1 /CLONE=IMAGE:3859303 /UG=Hs.266784 ESTs BF032808 chloride intracellular channel 5 CLIC5 53405 NM_001114086 /// NM_001256023 /// NM_016929 /// NR_045672 /// NR_045673 /// NR_045674 /// XM_006715114 /// XM_006715115 0002021 // response to dietary excess // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217629_at AA365670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA365670 /FEA=EST /DB_XREF=gi:2018010 /DB_XREF=est:EST76509 /UG=Hs.261526 ESTs AA365670 217630_at AI188346 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI188346 /FEA=EST /DB_XREF=gi:3739555 /DB_XREF=est:qd08a10.x1 /CLONE=IMAGE:1723098 /UG=Hs.301776 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI188346 angel homolog 2 (Drosophila) ANGEL2 90806 NM_144567 /// XM_005273344 /// XM_005273345 /// XM_005273346 /// XM_005273347 /// XM_005273349 /// XM_006711616 /// XR_247045 217631_at AI081107 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI081107 /FEA=EST /DB_XREF=gi:3417899 /DB_XREF=est:oz62d06.x1 /CLONE=IMAGE:1679915 /UG=Hs.315170 ESTs, Moderately similar to ALU2_HUMAN ALU SUBFAMILY SB SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI081107 GTP binding protein 4 GTPBP4 23560 NM_012341 /// XM_006717437 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0033342 // negative regulation of collagen binding // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217632_at BF035279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF035279 /FEA=EST /DB_XREF=gi:10743006 /DB_XREF=est:601457165F1 /CLONE=IMAGE:3860633 /UG=Hs.20325 ESTs, Moderately similar to pot. ORF V H.sapiens BF035279 guanine nucleotide binding protein-like 3 (nucleolar)-like GNL3L 54552 NM_001184819 /// NM_019067 0006184 // GTP catabolic process // not recorded /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217633_at AW513509 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW513509 /FEA=EST /DB_XREF=gi:7151587 /DB_XREF=est:xo46d08.x1 /CLONE=IMAGE:2707023 /UG=Hs.254679 ESTs, Highly similar to Y539_HUMAN HYPOTHETICAL PROTEIN KIAA0539 H.sapiens AW513509 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) URB1 9875 NM_014825 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217634_at AW872377 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW872377 /FEA=EST /DB_XREF=gi:8006430 /DB_XREF=est:hl91b01.x1 /CLONE=IMAGE:3009289 /UG=Hs.222153 ESTs, Moderately similar to archvillin H.sapiens AW872377 supervillin SVIL 6840 NM_003174 /// NM_021738 /// XM_005252564 /// XM_005252565 /// XM_005252566 /// XM_005252567 /// XM_005252568 /// XM_005252569 /// XM_005252570 /// XM_005252571 /// XM_005252572 /// XM_005252573 /// XM_006717492 /// XM_006717493 /// XM_006717494 /// XM_006717495 /// XM_006717496 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0071437 // invadopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 217635_s_at AA769006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA769006 /FEA=EST /DB_XREF=gi:2820244 /DB_XREF=est:oa80c10.s1 /CLONE=IMAGE:1318578 /UG=Hs.290921 ESTs, Highly similar to G02750 DNA-directed DNA polymerase H.sapiens AA769006 polymerase (DNA directed), gamma POLG 5428 NM_001126131 /// NM_002693 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 217636_at AA769006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA769006 /FEA=EST /DB_XREF=gi:2820244 /DB_XREF=est:oa80c10.s1 /CLONE=IMAGE:1318578 /UG=Hs.290921 ESTs, Highly similar to G02750 DNA-directed DNA polymerase H.sapiens AA769006 polymerase (DNA directed), gamma POLG 5428 NM_001126131 /// NM_002693 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 217637_at R25692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R25692 /FEA=EST /DB_XREF=gi:781827 /DB_XREF=est:yg44f12.r2 /CLONE=IMAGE:35277 /UG=Hs.224829 ESTs R25692 potassium voltage-gated channel, Shab-related subfamily, member 1 KCNB1 3745 NM_004975 /// XM_006723784 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032809 // neuronal cell body membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015271 // outward rectifier potassium channel activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 217638_at BF939092 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939092 /FEA=EST /DB_XREF=gi:12356412 /DB_XREF=est:7r05c01.x1 /CLONE=IMAGE:3706753 /UG=Hs.136090 ESTs BF939092 217639_at BF674749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF674749 /FEA=EST /DB_XREF=gi:11948644 /DB_XREF=est:602136893F1 /CLONE=IMAGE:4273270 /UG=Hs.258800 ESTs BF674749 217640_x_at BF038461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF038461 /FEA=EST /DB_XREF=gi:10744356 /DB_XREF=est:601460522F1 /CLONE=IMAGE:3863956 /UG=Hs.271252 ESTs, Moderately similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens BF038461 spindle and kinetochore associated complex subunit 1 SKA1 220134 NM_001039535 /// NM_145060 /// XR_243848 /// XR_254237 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from direct assay /// 0051301 // cell division // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay 217641_at AA634446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA634446 /FEA=EST /DB_XREF=gi:2557660 /DB_XREF=est:zu79e01.s1 /CLONE=IMAGE:744216 /UG=Hs.116840 ESTs AA634446 G protein-coupled receptor 135 GPR135 64582 NM_022571 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004992 // platelet activating factor receptor activity // traceable author statement 217642_at AI379492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI379492 /FEA=EST /DB_XREF=gi:4189345 /DB_XREF=est:tc64a03.x1 /CLONE=IMAGE:2069356 /UG=Hs.254292 ESTs AI379492 ring finger protein 40, E3 ubiquitin protein ligase RNF40 9810 NM_001207033 /// NM_001207034 /// NM_001286572 /// NM_014771 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033523 // histone H2B ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0033503 // HULC complex // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217643_x_at AA443771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA443771 /FEA=EST /DB_XREF=gi:2156446 /DB_XREF=est:zw95f08.s1 /CLONE=IMAGE:784743 /UG=Hs.270138 ESTs AA443771 217644_s_at AI276593 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI276593 /FEA=EST /DB_XREF=gi:3898867 /DB_XREF=est:ql71f08.x1 /CLONE=IMAGE:1877799 /UG=Hs.333042 Homo sapiens similar to son of sevenless (Drosophila) homolog 1 (H. sapiens) (LOC63378), mRNA AI276593 son of sevenless homolog 2 (Drosophila) SOS2 6655 NM_006939 /// XM_005268021 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217645_at AW088547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW088547 /FEA=EST /DB_XREF=gi:6044358 /DB_XREF=est:xd17c08.x1 /CLONE=IMAGE:2594030 /UG=Hs.312076 ESTs, Moderately similar to ALU2_HUMAN ALU SUBFAMILY SB SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW088547 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) /// SYNJ2BP-COX16 readthrough COX16 /// SYNJ2BP-COX16 51241 /// 100529257 NM_001202547 /// NM_001202548 /// NM_001202549 /// NM_001204090 /// NM_016468 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 217646_at AW449390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW449390 /FEA=EST /DB_XREF=gi:6990166 /DB_XREF=est:UI-H-BI3-aki-g-10-0-UI.s1 /CLONE=IMAGE:2734650 /UG=Hs.257150 ESTs, Moderately similar to SUR1_HUMAN SURFEIT LOCUS PROTEIN 1 H.sapiens AW449390 surfeit 1 SURF1 6834 NM_001280787 /// NM_003172 /// XM_006717255 /// XM_006717256 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217647_at AA070330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA070330 /FEA=EST /DB_XREF=gi:1577689 /DB_XREF=est:zm68e06.r1 /CLONE=IMAGE:530818 /UG=Hs.283729 ESTs AA070330 dihydroorotate dehydrogenase (quinone) DHODH 1723 NM_001025193 /// NM_001361 /// XM_005255827 /// XM_005255828 /// XM_005255829 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090140 // regulation of mitochondrial fission // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004152 // dihydroorotate dehydrogenase activity // traceable author statement /// 0004158 // dihydroorotate oxidase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from electronic annotation 217648_at AW295367 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW295367 /FEA=EST /DB_XREF=gi:6702003 /DB_XREF=est:UI-H-BI2-ahv-e-04-0-UI.s1 /CLONE=IMAGE:2728039 /UG=Hs.196585 ESTs, Weakly similar to Pro-Pol-dUTPase polyprotein M.musculus AW295367 217649_at AV702306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV702306 /FEA=EST /DB_XREF=gi:10718636 /DB_XREF=est:AV702306 /CLONE=ADBBID05 /UG=Hs.321211 ESTs, Highly similar to zinc finger protein 216 splice variant 1 H.sapiens AV702306 zinc finger, AN1-type domain 5 ZFAND5 7763 NM_001102420 /// NM_001102421 /// NM_001278243 /// NM_001278244 /// NM_001278245 /// NM_006007 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217650_x_at AI088162 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI088162 /FEA=EST /DB_XREF=gi:3427138 /DB_XREF=est:oz96b09.x1 /CLONE=IMAGE:1683161 /UG=Hs.262292 ESTs, Moderately similar to ALU3_HUMAN ALU SUBFAMILY SB1 SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI088162 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 ST3GAL2 6483 NM_006927 0005975 // carbohydrate metabolic process // traceable author statement /// 0006040 // amino sugar metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from electronic annotation /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 217651_at BF512531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF512531 /FEA=EST /DB_XREF=gi:11597710 /DB_XREF=est:UI-H-BW1-amf-b-05-0-UI.s1 /CLONE=IMAGE:3069633 /UG=Hs.297765 ESTs BF512531 217652_at AW157731 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW157731 /FEA=EST /DB_XREF=gi:6229132 /DB_XREF=est:au86b01.x1 /CLONE=IMAGE:2783113 /UG=Hs.270982 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW157731 MAU2 sister chromatid cohesion factor MAU2 23383 NM_015329 /// XM_005259837 /// XM_005259838 /// XM_006722711 /// XR_430132 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032116 // SMC loading complex // inferred from direct assay /// 0032116 // SMC loading complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 217653_x_at AW150065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW150065 /FEA=EST /DB_XREF=gi:6197971 /DB_XREF=est:xg48a10.x1 /CLONE=IMAGE:2630778 /UG=Hs.271957 ESTs AW150065 217654_at R71245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R71245 /FEA=EST /DB_XREF=gi:844762 /DB_XREF=est:yi54e05.s1 /CLONE=IMAGE:143072 /UG=Hs.174303 ESTs R71245 CASP8 and FADD-like apoptosis regulator CFLAR 8837 NM_001127183 /// NM_001127184 /// NM_001202515 /// NM_001202516 /// NM_001202517 /// NM_001202518 /// NM_001202519 /// NM_003879 /// XM_005246935 /// XM_005246936 /// XM_005246937 /// XM_005246938 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0014732 // skeletal muscle atrophy // inferred from sequence or structural similarity /// 0014842 // regulation of satellite cell proliferation // inferred from sequence or structural similarity /// 0014866 // skeletal myofibril assembly // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0060544 // regulation of necroptotic process // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901740 // negative regulation of myoblast fusion // inferred from sequence or structural similarity /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0035877 // death effector domain binding // not recorded 217655_at BE552409 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE552409 /FEA=EST /DB_XREF=gi:9794101 /DB_XREF=est:hy07f08.x1 /CLONE=IMAGE:3196647 /UG=Hs.280895 ESTs BE552409 uncharacterized LOC100127972 LOC100127972 100127972 XR_038157 /// XR_038736 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0030033 // microvillus assembly // non-traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0046588 // negative regulation of calcium-dependent cell-cell adhesion // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from direct assay 217656_at AW128846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW128846 /FEA=EST /DB_XREF=gi:6116764 /DB_XREF=est:xd46f06.x1 /CLONE=IMAGE:2596835 /UG=Hs.244737 ESTs, Weakly similar to neuronal thread protein AD7c-NTP H.sapiens AW128846 217657_at AL583687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583687 /FEA=EST /DB_XREF=gi:12952889 /DB_XREF=est:AL583687 /CLONE=CS0DJ008YL09 (5 prime) /UG=Hs.134852 ESTs AL583687 217658_at BF448596 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF448596 /FEA=EST /DB_XREF=gi:11514774 /DB_XREF=est:7n90b04.x1 /CLONE=IMAGE:3571902 /UG=Hs.290484 ESTs BF448596 THAP domain containing, apoptosis associated protein 3 THAP3 90326 NM_001195752 /// NM_001195753 /// NM_138350 /// XM_005263532 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217659_at AA457019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA457019 /FEA=EST /DB_XREF=gi:2179739 /DB_XREF=est:aa38a06.s1 /CLONE=IMAGE:815506 /UG=Hs.280645 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA457019 217660_at AW188214 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188214 /FEA=EST /DB_XREF=gi:6462650 /DB_XREF=est:xj93g09.x1 /CLONE=IMAGE:2664832 /UG=Hs.250389 ESTs, Weakly similar to A59252 myosin heavy chain, nonmuscle, form IIB H.sapiens AW188214 myosin, heavy chain 14, non-muscle MYH14 79784 NM_001077186 /// NM_001145809 /// NM_024729 /// XM_006723386 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from mutant phenotype /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 217661_x_at AW513514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW513514 /FEA=EST /DB_XREF=gi:7151592 /DB_XREF=est:xo46e09.x1 /CLONE=IMAGE:2707048 /UG=Hs.271243 ESTs, Weakly similar to SIX4 H.sapiens AW513514 SIX homeobox 5 SIX5 147912 NM_175875 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217662_x_at AI393960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI393960 /FEA=EST /DB_XREF=gi:4223507 /DB_XREF=est:tg11d04.x1 /CLONE=IMAGE:2108455 /UG=Hs.274851 ESTs AI393960 217663_at AW264320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW264320 /FEA=EST /DB_XREF=gi:6641062 /DB_XREF=est:xq98c06.x1 /CLONE=IMAGE:2758666 /UG=Hs.235992 ESTs AW264320 zinc finger protein 234 ZNF234 10780 NM_001144824 /// NM_006630 /// XM_006722973 /// XM_006722974 /// XM_006722975 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 217664_at AA780524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA780524 /FEA=EST /DB_XREF=gi:2839855 /DB_XREF=est:ac71f01.s1 /CLONE=IMAGE:868057 /UG=Hs.294072 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA780524 217665_at AA420614 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA420614 /FEA=EST /DB_XREF=gi:2094586 /DB_XREF=est:nc62g02.r1 /CLONE=IMAGE:745874 /UG=Hs.188826 ESTs, Moderately similar to G02654 ribosomal protein L39 H.sapiens AA420614 zinc finger protein 813 ZNF813 126017 NM_001004301 /// XM_006723006 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217666_at AW974481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974481 /FEA=EST /DB_XREF=gi:8165680 /DB_XREF=est:EST386585 /UG=Hs.293755 ESTs AW974481 217667_at AV761014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV761014 /FEA=EST /DB_XREF=gi:10918862 /DB_XREF=est:AV761014 /CLONE=MDSCCF09 /UG=Hs.291972 ESTs, Moderately similar to SC14_HUMAN SEC14-LIKE PROTEIN H.sapiens AV761014 SEC14-like 1 pseudogene 1 SEC14L1P1 729799 NR_026952 217668_at BF511164 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511164 /FEA=EST /DB_XREF=gi:11594462 /DB_XREF=est:UI-H-BI4-aoi-a-09-0-UI.s1 /CLONE=IMAGE:3084952 /UG=Hs.293309 ESTs BF511164 leucine rich repeat containing 75B LRRC75B 388886 NM_207644 /// XM_005261600 /// XR_244373 217669_s_at AW451230 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451230 /FEA=EST /DB_XREF=gi:6992006 /DB_XREF=est:UI-H-BI3-alh-a-01-0-UI.s1 /CLONE=IMAGE:2736649 /UG=Hs.257332 ESTs, Highly similar to KIAA0311 H.sapiens AW451230 A kinase (PRKA) anchor protein 6 AKAP6 9472 NM_004274 /// XM_005268219 0001508 // action potential // inferred by curator /// 0006605 // protein targeting // non-traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from sequence or structural similarity /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0032514 // positive regulation of protein phosphatase type 2B activity // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from sequence or structural similarity /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0061051 // positive regulation of cell growth involved in cardiac muscle cell development // inferred from sequence or structural similarity /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 1902261 // positive regulation of delayed rectifier potassium channel activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity /// 0034237 // protein kinase A regulatory subunit binding // inferred from sequence or structural similarity /// 0043495 // protein anchor // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0051018 // protein kinase A binding // non-traceable author statement /// 0051018 // protein kinase A binding // traceable author statement 217670_at AW149827 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149827 /FEA=EST /DB_XREF=gi:6197723 /DB_XREF=est:xf42g03.x1 /CLONE=IMAGE:2620756 /UG=Hs.293272 ESTs, Weakly similar to ALUF_HUMAN !!!! ALU CLASS F WARNING ENTRY !!! H.sapiens AW149827 ribosomal protein, large, P2 RPLP2 6181 NM_001004 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 217671_at BE466926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE466926 /FEA=EST /DB_XREF=gi:9512701 /DB_XREF=est:hz59a04.x1 /CLONE=IMAGE:3212238 /UG=Hs.279706 ESTs BE466926 Down syndrome encephalopathy related protein 1 DSERG1 751816 XR_108924 /// XR_113209 /// XR_171762 217672_x_at BF114906 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF114906 /FEA=EST /DB_XREF=gi:10984382 /DB_XREF=est:7i88e12.x1 /CLONE=IMAGE:3341806 /UG=Hs.288411 ESTs BF114906 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 217673_x_at AA650558 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA650558 /FEA=EST /DB_XREF=gi:2577886 /DB_XREF=est:nt02g10.s1 /CLONE=IMAGE:1192002 /UG=Hs.325202 ESTs, Highly similar to GBAS_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT H.sapiens AA650558 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 217674_at AA923707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA923707 /FEA=EST /DB_XREF=gi:3068973 /DB_XREF=est:om39a05.s1 /CLONE=IMAGE:1543376 /UG=Hs.234410 ESTs AA923707 217675_at BE734331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE734331 /FEA=EST /DB_XREF=gi:10148323 /DB_XREF=est:601565557F1 /CLONE=IMAGE:3840279 /UG=Hs.255739 ESTs, Weakly similar to Z205_HUMAN ZINC FINGER PROTEIN 205 H.sapiens BE734331 zinc finger and BTB domain containing 7C ZBTB7C 201501 NM_001039360 /// XM_005258227 /// XM_005258229 /// XM_005258230 /// XM_006722417 /// XM_006722418 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217676_at AA071454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA071454 /FEA=EST /DB_XREF=gi:1578817 /DB_XREF=est:zm73c03.s1 /CLONE=IMAGE:531268 /UG=Hs.258725 ESTs, Moderately similar to ATPO_HUMAN ATP SYNTHASE OLIGOMYCIN SENSITIVITY CONFERRAL PROTEIN PRECURSOR, MITOCHONDRIAL H.sapiens AA071454 217677_at BF542055 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF542055 /FEA=EST /DB_XREF=gi:11629436 /DB_XREF=est:602068320F1 /CLONE=IMAGE:4067357 /UG=Hs.190785 ESTs BF542055 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 PLEKHA2 59339 NM_021623 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0001968 // fibronectin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from mutant phenotype 217678_at AA488687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA488687 /FEA=EST /DB_XREF=gi:2216118 /DB_XREF=est:ab38f03.s1 /CLONE=IMAGE:843101 /UG=Hs.284235 ESTs AA488687 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 SLC7A11 23657 NM_014331 /// XM_005262875 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0015813 // L-glutamate transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015327 // cystine:glutamate antiporter activity // traceable author statement 217679_x_at AI683552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI683552 /FEA=EST /DB_XREF=gi:4893734 /DB_XREF=est:tx67h02.x1 /CLONE=IMAGE:2274675 /UG=Hs.201605 ESTs, Moderately similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI683552 217680_x_at BG151284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG151284 /FEA=EST /DB_XREF=gi:12663314 /DB_XREF=est:nai35h10.y1 /CLONE=IMAGE:4262274 /UG=Hs.322737 ESTs BG151284 ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70 RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217681_at BE736994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE736994 /FEA=EST /DB_XREF=gi:10150897 /DB_XREF=est:601306614F1 /CLONE=IMAGE:3641210 /UG=Hs.211280 ESTs, Weakly similar to WN7A_HUMAN WNT-7A PROTEIN PRECURSOR H.sapiens BE736994 wingless-type MMTV integration site family, member 7B WNT7B 7477 NM_058238 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0003338 // metanephros morphogenesis // inferred from sequence or structural similarity /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // not recorded /// 0016055 // Wnt signaling pathway // inferred from sequence or structural similarity /// 0016332 // establishment or maintenance of polarity of embryonic epithelium // inferred from sequence or structural similarity /// 0021871 // forebrain regionalization // inferred from expression pattern /// 0022009 // central nervous system vasculogenesis // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from expression pattern /// 0030324 // lung development // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from sequence or structural similarity /// 0032536 // regulation of cell projection size // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042592 // homeostatic process // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // not recorded /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // not recorded /// 0048144 // fibroblast proliferation // inferred from expression pattern /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060425 // lung morphogenesis // inferred from sequence or structural similarity /// 0060428 // lung epithelium development // inferred from sequence or structural similarity /// 0060482 // lobar bronchus development // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060535 // trachea cartilage morphogenesis // inferred from sequence or structural similarity /// 0060560 // developmental growth involved in morphogenesis // inferred from sequence or structural similarity /// 0060669 // embryonic placenta morphogenesis // inferred from sequence or structural similarity /// 0060710 // chorio-allantoic fusion // inferred from sequence or structural similarity /// 0061180 // mammary gland epithelium development // inferred from expression pattern /// 0070307 // lens fiber cell development // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from expression pattern /// 0072053 // renal inner medulla development // inferred from sequence or structural similarity /// 0072054 // renal outer medulla development // inferred from sequence or structural similarity /// 0072060 // outer medullary collecting duct development // inferred from sequence or structural similarity /// 0072061 // inner medullary collecting duct development // inferred from sequence or structural similarity /// 0072089 // stem cell proliferation // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from sequence or structural similarity /// 0072207 // metanephric epithelium development // inferred from sequence or structural similarity /// 0072236 // metanephric loop of Henle development // inferred from sequence or structural similarity /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0005201 // extracellular matrix structural constituent // non-traceable author statement 217682_at AW503390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW503390 /FEA=EST /DB_XREF=gi:7118730 /DB_XREF=est:UI-HF-BN0-akw-c-02-0-UI.r1 /CLONE=IMAGE:3078507 /UG=Hs.135258 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW503390 RP11-473I1.9 217683_at AA115963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA115963 /FEA=EST /DB_XREF=gi:1670996 /DB_XREF=est:zm78d11.s1 /CLONE=IMAGE:531765 /UG=Hs.323423 ESTs, Moderately similar to B Chain B, Crystal Structure Of Deoxy-Human Hemoglobin Beta6 Glu->trp H.sapiens AA115963 hemoglobin, epsilon 1 HBE1 3046 NM_005330 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015671 // oxygen transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031721 // hemoglobin alpha binding // inferred from electronic annotation 217684_at BG281679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG281679 /FEA=EST /DB_XREF=gi:13030605 /DB_XREF=est:602402364F1 /CLONE=IMAGE:4544871 /UG=Hs.141307 ESTs, Highly similar to YXHUT thymidylate synthase H.sapiens BG281679 thymidylate synthetase TYMS 7298 NM_001071 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006231 // dTMP biosynthetic process // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019088 // immortalization of host cell by virus // inferred from electronic annotation /// 0019860 // uracil metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046078 // dUMP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004799 // thymidylate synthase activity // traceable author statement /// 0005542 // folic acid binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 217685_at AA853175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA853175 /FEA=EST /DB_XREF=gi:2939914 /DB_XREF=est:NHTBCae03g02r1 /CLONE=NHTBCae03g02 /UG=Hs.333049 Homo sapiens similar to solute carrier family 16 (monocarboxylic acid transporters), member 3 (H. sapiens) (LOC65816), mRNA AA853175 217686_at BF222916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222916 /FEA=EST /DB_XREF=gi:11130093 /DB_XREF=est:7q25a04.x1 /CLONE=IMAGE:3699342 /UG=Hs.331207 ESTs BF222916 protein tyrosine phosphatase, non-receptor type 1 PTPN1 5770 NM_001278618 /// NM_002827 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1990264 // peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity // inferred from sequence or structural similarity 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from physical interaction 217687_at AA224446 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA224446 /FEA=EST /DB_XREF=gi:1844989 /DB_XREF=est:zr16a03.r1 /CLONE=IMAGE:663532 /UG=Hs.311561 ESTs, Weakly similar to CYA7_HUMAN ADENYLATE CYCLASE, TYPE VII H.sapiens AA224446 adenylate cyclase 2 (brain) ADCY2 108 NM_020546 /// XR_427657 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from sequence or structural similarity /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005622 // intracellular // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008179 // adenylate cyclase binding // inferred from sequence or structural similarity /// 0008294 // calcium- and calmodulin-responsive adenylate cyclase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 217688_at BE677757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE677757 /FEA=EST /DB_XREF=gi:10038372 /DB_XREF=est:7f59g09.x1 /CLONE=IMAGE:3299008 /UG=Hs.311561 ESTs, Weakly similar to CYA7_HUMAN ADENYLATE CYCLASE, TYPE VII H.sapiens BE677757 217689_at BG109555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG109555 /FEA=EST /DB_XREF=gi:12603061 /DB_XREF=est:602280658F1 /CLONE=IMAGE:4367966 /UG=Hs.331207 ESTs BG109555 protein tyrosine phosphatase, non-receptor type 1 PTPN1 5770 NM_001278618 /// NM_002827 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1990264 // peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity // inferred from sequence or structural similarity 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from physical interaction 217690_at BG281679 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG281679 /FEA=EST /DB_XREF=gi:13030605 /DB_XREF=est:602402364F1 /CLONE=IMAGE:4544871 /UG=Hs.141307 ESTs, Highly similar to YXHUT thymidylate synthase H.sapiens BG281679 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 217691_x_at AA853175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA853175 /FEA=EST /DB_XREF=gi:2939914 /DB_XREF=est:NHTBCae03g02r1 /CLONE=NHTBCae03g02 /UG=Hs.333049 Homo sapiens similar to solute carrier family 16 (monocarboxylic acid transporters), member 3 (H. sapiens) (LOC65816), mRNA AA853175 microRNA 6787 /// solute carrier family 16 (monocarboxylate transporter), member 3 MIR6787 /// SLC16A3 9123 /// 102465472 NM_001042422 /// NM_001042423 /// NM_001206950 /// NM_001206951 /// NM_001206952 /// NM_004207 /// NR_106845 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217692_at AW371924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW371924 /FEA=EST /DB_XREF=gi:6876578 /DB_XREF=est:RC4-BT0311-251199-012-a07 /UG=Hs.313848 ESTs, Moderately similar to MGN_HUMAN MAGO NASHI PROTEIN HOMOLOG H.sapiens AW371924 mago-nashi homolog 2 (pseudogene) MAGOH2 100506898 NR_049723 217693_x_at AW469555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW469555 /FEA=EST /DB_XREF=gi:7039661 /DB_XREF=est:hd19g06.x1 /CLONE=IMAGE:2910010 /UG=Hs.313848 ESTs, Moderately similar to MGN_HUMAN MAGO NASHI PROTEIN HOMOLOG H.sapiens AW469555 mago-nashi homolog 2 (pseudogene) MAGOH2 100506898 NR_049723 217694_at AV687010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV687010 /FEA=EST /DB_XREF=gi:10288873 /DB_XREF=est:AV687010 /CLONE=GKCAYC04 /UG=Hs.284651 ESTs AV687010 217695_x_at BF942161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF942161 /FEA=EST /DB_XREF=gi:12359481 /DB_XREF=est:nae87g10.x1 /CLONE=IMAGE:4118994 /UG=Hs.302797 ESTs BF942161 217696_at AA767713 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA767713 /FEA=EST /DB_XREF=gi:2818728 /DB_XREF=est:ob49b11.s1 /CLONE=IMAGE:1334685 /UG=Hs.325905 ESTs AA767713 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) FUT7 2529 NM_004479 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0002522 // leukocyte migration involved in immune response // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0036065 // fucosylation // inferred from electronic annotation /// 0036065 // fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008417 // fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046920 // alpha-(1->3)-fucosyltransferase activity // traceable author statement 217697_at AV661514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV661514 /FEA=EST /DB_XREF=gi:9882528 /DB_XREF=est:AV661514 /CLONE=GLCGTC04 /UG=Hs.282693 ESTs AV661514 217698_at AV651668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV651668 /FEA=EST /DB_XREF=gi:9872682 /DB_XREF=est:AV651668 /CLONE=GLCCSC04 /UG=Hs.282480 ESTs AV651668 217699_at AV700338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700338 /FEA=EST /DB_XREF=gi:10302309 /DB_XREF=est:AV700338 /CLONE=GKCAMH12 /UG=Hs.286243 ESTs AV700338 217700_at AI818951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI818951 /FEA=EST /DB_XREF=gi:5438030 /DB_XREF=est:wj89e12.x1 /CLONE=IMAGE:2410030 /UG=Hs.270614 ESTs, Weakly similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI818951 canopy FGF signaling regulator 4 CNPY4 245812 NM_152755 0005576 // extracellular region // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation 217701_x_at AA653456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA653456 /FEA=EST /DB_XREF=gi:2589627 /DB_XREF=est:ag66c08.s1 /CLONE=IMAGE:1127918 /UG=Hs.270495 ESTs, Weakly similar to ubiquitous TPR motif, Y isoform H.sapiens AA653456 217702_at AW295066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW295066 /FEA=EST /DB_XREF=gi:6701702 /DB_XREF=est:UI-H-BW0-ait-b-09-0-UI.s1 /CLONE=IMAGE:2730209 /UG=Hs.255387 ESTs AW295066 interleukin 27 receptor, alpha IL27RA 9466 NM_004843 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0048302 // regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0070106 // interleukin-27-mediated signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0045509 // interleukin-27 receptor activity // inferred from electronic annotation 217703_x_at AA401963 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA401963 /FEA=EST /DB_XREF=gi:2055965 /DB_XREF=est:zu53c08.s1 /CLONE=IMAGE:741710 /UG=Hs.194107 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA401963 217704_x_at AI820796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI820796 /FEA=EST /DB_XREF=gi:5439875 /DB_XREF=est:an35h08.x5 /CLONE=IMAGE:1700703 /UG=Hs.310806 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI820796 217705_at AW085172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW085172 /FEA=EST /DB_XREF=gi:6040324 /DB_XREF=est:xe06g09.x1 /CLONE=IMAGE:2606368 /UG=Hs.243366 ESTs, Highly similar to KPCM_HUMAN PROTEIN KINASE C, MU TYPE H.sapiens AW085172 protein kinase D1 PRKD1 5587 NM_002742 /// XM_005267859 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from genetic interaction /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0010837 // regulation of keratinocyte proliferation // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from genetic interaction /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from genetic interaction /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from genetic interaction /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from genetic interaction /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from genetic interaction /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045766 // positive regulation of angiogenesis // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 1901727 // positive regulation of histone deacetylase activity // inferred from genetic interaction /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype /// 2001044 // regulation of integrin-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 217706_at AV742010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV742010 /FEA=EST /DB_XREF=gi:10859591 /DB_XREF=est:AV742010 /CLONE=CBCCJH10 /UG=Hs.317243 ESTs AV742010 217707_x_at AI535683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI535683 /FEA=EST /DB_XREF=gi:4449818 /DB_XREF=est:cong1.P11.A9 /UG=Hs.327729 ESTs AI535683 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SMARCA2 6595 NM_001289396 /// NM_001289397 /// NM_001289398 /// NM_001289399 /// NM_001289400 /// NM_003070 /// NM_139045 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0035887 // aortic smooth muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 217708_x_at AI734156 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI734156 /FEA=EST /DB_XREF=gi:5055269 /DB_XREF=est:nc79d04.y5 /CLONE=IMAGE:783559 /UG=Hs.172895 ESTs AI734156 217709_at AV647366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV647366 /FEA=EST /DB_XREF=gi:9868380 /DB_XREF=est:AV647366 /CLONE=GLCAXE09 /UG=Hs.282365 ESTs AV647366 217710_x_at AI075181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI075181 /FEA=EST /DB_XREF=gi:3401772 /DB_XREF=est:oy96b04.x1 /CLONE=IMAGE:1673647 /UG=Hs.304000 ESTs, Highly similar to inositol 1,3,4-trisphosphate 56-kinase H.sapiens AI075181 inositol-tetrakisphosphate 1-kinase ITPK1 3705 NM_001142593 /// NM_001142594 /// NM_014216 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047325 // inositol tetrakisphosphate 1-kinase activity // traceable author statement /// 0052725 // inositol-1,3,4-trisphosphate 6-kinase activity // traceable author statement /// 0052726 // inositol-1,3,4-trisphosphate 5-kinase activity // traceable author statement /// 0052825 // inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity // traceable author statement /// 0052830 // inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity // traceable author statement /// 0052831 // inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity // traceable author statement /// 0052835 // inositol-3,4,6-trisphosphate 1-kinase activity // traceable author statement 217711_at BF594294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF594294 /FEA=EST /DB_XREF=gi:11686618 /DB_XREF=est:7h79c12.x1 /CLONE=IMAGE:3322198 /UG=Hs.287335 ESTs, Highly similar to AC15_HUMAN ACTIVATOR 1 140 KDA SUBUNIT H.sapiens BF594294 TEK tyrosine kinase, endothelial TEK 7010 NM_000459 /// NM_001290077 /// NM_001290078 /// XM_005251561 /// XM_005251562 /// XM_005251563 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048014 // Tie signaling pathway // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060216 // definitive hemopoiesis // traceable author statement /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0072012 // glomerulus vasculature development // inferred from sequence or structural similarity /// 1902533 // positive regulation of intracellular signal transduction // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype /// 2000351 // regulation of endothelial cell apoptotic process // traceable author statement /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 217712_at AA479678 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA479678 /FEA=EST /DB_XREF=gi:2205564 /DB_XREF=est:zu43a04.s1 /CLONE=IMAGE:740718 /UG=Hs.203269 ESTs, Moderately similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA479678 217713_x_at AA126763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA126763 /FEA=EST /DB_XREF=gi:1686263 /DB_XREF=est:zn87b11.s1 /CLONE=IMAGE:565149 /UG=Hs.182296 ESTs, Weakly similar to ALU6_HUMAN ALU SUBFAMILY SP SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA126763 217714_x_at AV756729 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV756729 /FEA=EST /DB_XREF=gi:10914577 /DB_XREF=est:AV756729 /CLONE=BMCACB11 /UG=Hs.317661 ESTs AV756729 microRNA 3917 /// stathmin 1 MIR3917 /// STMN1 3925 /// 100500808 NM_001145454 /// NM_005563 /// NM_152497 /// NM_203399 /// NM_203401 /// NR_037481 0007019 // microtubule depolymerization // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay 217715_x_at BE045142 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE045142 /FEA=EST /DB_XREF=gi:8362195 /DB_XREF=est:hn26h02.x1 /CLONE=IMAGE:3023283 /UG=Hs.274907 ESTs BE045142 217716_s_at NM_013336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013336.1 /DEF=Homo sapiens sec61 homolog (HSEC61), mRNA. /FEA=mRNA /GEN=HSEC61 /PROD=sec61 homolog /DB_XREF=gi:7019414 /UG=Hs.306079 sec61 homolog /FL=gb:BC002951.1 gb:AF346602.1 gb:AF084458.1 gb:NM_013336.1 NM_013336 Sec61 alpha 1 subunit (S. cerevisiae) SEC61A1 29927 NM_013336 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016049 // cell growth // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045047 // protein targeting to ER // inferred from sequence or structural similarity /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from sequence or structural similarity 217717_s_at BF246499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF246499 /FEA=EST /DB_XREF=gi:11160924 /DB_XREF=est:601854744F1 /CLONE=IMAGE:4074659 /UG=Hs.182238 GW128 protein /FL=gb:AF107406.1 gb:NM_014052.1 BF246499 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta YWHAB 7529 NM_003404 /// NM_139323 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051220 // cytoplasmic sequestering of protein // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 217718_s_at NM_014052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014052.1 /DEF=Homo sapiens GW128 protein (GW128), mRNA. /FEA=mRNA /GEN=GW128 /PROD=GW128 protein /DB_XREF=gi:7661715 /UG=Hs.182238 GW128 protein /FL=gb:AF107406.1 gb:NM_014052.1 NM_014052 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta YWHAB 7529 NM_003404 /// NM_139323 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035308 // negative regulation of protein dephosphorylation // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051220 // cytoplasmic sequestering of protein // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 217719_at NM_016091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016091.1 /DEF=Homo sapiens HSPC025 (HSPC025), mRNA. /FEA=mRNA /GEN=HSPC025 /PROD=HSPC025 /DB_XREF=gi:7705432 /UG=Hs.119503 HSPC025 /FL=gb:BC001101.1 gb:AF077207.1 gb:AF083243.1 gb:NM_016091.1 NM_016091 eukaryotic translation initiation factor 3, subunit L EIF3L 51386 NM_001242923 /// NM_016091 /// XM_005261625 /// XM_006724260 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0001650 // fibrillar center // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217720_at NM_016139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016139.1 /DEF=Homo sapiens 16.7Kd protein (LOC51142), mRNA. /FEA=mRNA /GEN=LOC51142 /PROD=16.7Kd protein /DB_XREF=gi:7705850 /UG=Hs.180859 16.7Kd protein /FL=gb:BC003079.1 gb:AF078845.1 gb:NM_016139.1 NM_016139 coiled-coil-helix-coiled-coil-helix domain containing 2 CHCHD2 51142 NM_016139 0005739 // mitochondrion // inferred from direct assay 217721_at BE551361 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE551361 /FEA=EST /DB_XREF=gi:9793053 /DB_XREF=est:7b63f12.x1 /CLONE=IMAGE:3232943 /UG=Hs.184326 CDC10 (cell division cycle 10, S. cerevisiae, homolog) /FL=gb:NM_001788.1 BE551361 septin 7 SEPT7 989 NM_001011553 /// NM_001242956 /// NM_001788 /// XM_006715806 /// XM_006715807 /// XM_006715808 /// XM_006715809 /// XM_006715810 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016476 // regulation of embryonic cell shape // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 217722_s_at NM_016645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016645.1 /DEF=Homo sapiens mesenchymal stem cell protein DSC92 (LOC51335), mRNA. /FEA=mRNA /GEN=LOC51335 /PROD=mesenchymal stem cell protein DSC92 /DB_XREF=gi:7706195 /UG=Hs.323467 mesenchymal stem cell protein DSC92 /FL=gb:AB029315.1 gb:AF242770.1 gb:NM_016645.1 NM_016645 neugrin, neurite outgrowth associated NGRN 51335 NM_001033088 /// NM_016645 /// NR_028052 0006464 // cellular protein modification process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217723_x_at BC002550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC002550.1 /DEF=Homo sapiens, ribosomal protein S12, clone MGC:663, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S12 /DB_XREF=gi:12803450 /UG=Hs.285405 ribosomal protein S12 /FL=gb:BC002550.1 gb:NM_001016.1 BC002550 217724_at AF131807 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131807.1 /DEF=Homo sapiens clone 25076 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406639 /UG=Hs.165998 PAI-1 mRNA-binding protein /FL=gb:AL080119.1 gb:NM_015640.1 AF131807 SERPINE1 mRNA binding protein 1 SERBP1 26135 NM_001018067 /// NM_001018068 /// NM_001018069 /// NM_015640 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217725_x_at NM_015640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015640.1 /DEF=Homo sapiens PAI-1 mRNA-binding protein (PAI-RBP1), mRNA. /FEA=mRNA /GEN=PAI-RBP1 /PROD=PAI-1 mRNA-binding protein /DB_XREF=gi:7661625 /UG=Hs.165998 PAI-1 mRNA-binding protein /FL=gb:AL080119.1 gb:NM_015640.1 NM_015640 SERPINE1 mRNA binding protein 1 SERBP1 26135 NM_001018067 /// NM_001018068 /// NM_001018069 /// NM_015640 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217726_at NM_016057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016057.1 /DEF=Homo sapiens CGI-120 protein (LOC51644), mRNA. /FEA=mRNA /GEN=LOC51644 /PROD=CGI-120 protein /DB_XREF=gi:7706336 /UG=Hs.181271 CGI-120 protein /FL=gb:AB047848.1 gb:BC002849.1 gb:AF151878.1 gb:AF161529.1 gb:NM_016057.1 NM_016057 coatomer protein complex, subunit zeta 1 COPZ1 22818 NM_001271734 /// NM_001271735 /// NM_001271736 /// NM_016057 /// NR_073424 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from direct assay /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 217727_x_at NM_018206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018206.1 /DEF=Homo sapiens vacuolar protein sorting 35 (yeast homolog) (VPS35), mRNA. /FEA=mRNA /GEN=VPS35 /PROD=vacuolar protein sorting 35 (yeast homolog) /DB_XREF=gi:8922645 /UG=Hs.264190 vacuolar protein sorting 35 (yeast homolog) /FL=gb:AF186382.1 gb:AL136888.1 gb:BC002414.1 gb:AF191298.2 gb:NM_018206.1 gb:AF175265.1 gb:AF183418.1 NM_018206 vacuolar protein sorting 35 homolog (S. cerevisiae) VPS35 55737 NM_018206 /// XM_005256045 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217728_at NM_014624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014624.2 /DEF=Homo sapiens S100 calcium-binding protein A6 (calcyclin) (S100A6), mRNA. /FEA=mRNA /GEN=S100A6 /PROD=S100 calcium-binding protein A6 /DB_XREF=gi:9845517 /UG=Hs.275243 S100 calcium-binding protein A6 (calcyclin) /FL=gb:BC001431.1 gb:NM_014624.2 NM_014624 S100 calcium binding protein A6 S100A6 6277 NM_014624 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // non-traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // non-traceable author statement 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay 217729_s_at NM_001130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001130.3 /DEF=Homo sapiens amino-terminal enhancer of split (AES), mRNA. /FEA=mRNA /GEN=AES /PROD=amino-terminal enhancer of split /DB_XREF=gi:6382065 /UG=Hs.244 amino-terminal enhancer of split /FL=gb:AF072902.1 gb:U04241.1 gb:NM_001130.3 NM_001130 amino-terminal enhancer of split AES 166 NM_001130 /// NM_198969 /// NM_198970 /// XM_006722664 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0060761 // negative regulation of response to cytokine stimulus // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000210 // positive regulation of anoikis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 217730_at NM_022152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022152.1 /DEF=Homo sapiens PP1201 protein (PP1201), mRNA. /FEA=mRNA /GEN=PP1201 /PROD=PP1201 protein /DB_XREF=gi:11545897 /UG=Hs.184052 PP1201 protein /FL=gb:NM_022152.1 NM_022152 microRNA 6513 /// transmembrane BAX inhibitor motif containing 1 MIR6513 /// TMBIM1 64114 /// 102465256 NM_022152 /// NR_106768 /// XM_005246758 /// XM_005246761 /// XM_005246762 0048553 // negative regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902045 // negative regulation of Fas signaling pathway // inferred from mutant phenotype /// 2000504 // positive regulation of blood vessel remodeling // inferred from sequence or structural similarity 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005123 // death receptor binding // inferred from direct assay 217731_s_at NM_021999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021999.1 /DEF=Homo sapiens integral membrane protein 2B (ITM2B), mRNA. /FEA=mRNA /GEN=ITM2B /PROD=integral membrane protein 2B /DB_XREF=gi:11527401 /UG=Hs.239625 integral membrane protein 2B /FL=gb:NM_021999.1 gb:AF136973.1 gb:BC000554.1 gb:AF092128.1 gb:AF152462.1 gb:AF246221.1 NM_021999 integral membrane protein 2B ITM2B 9445 NM_021999 0006915 // apoptotic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042985 // negative regulation of amyloid precursor protein biosynthetic process // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0031301 // integral component of organelle membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 217732_s_at AF092128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF092128.1 /DEF=Homo sapiens putative transmembrane protein E3-16 mRNA, complete cds. /FEA=mRNA /PROD=putative transmembrane protein E3-16 /DB_XREF=gi:5138905 /UG=Hs.239625 integral membrane protein 2B /FL=gb:NM_021999.1 gb:AF136973.1 gb:BC000554.1 gb:AF092128.1 gb:AF152462.1 gb:AF246221.1 AF092128 integral membrane protein 2B ITM2B 9445 NM_021999 0006915 // apoptotic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042985 // negative regulation of amyloid precursor protein biosynthetic process // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0031301 // integral component of organelle membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 217733_s_at NM_021103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021103.1 /DEF=Homo sapiens thymosin, beta 10 (TMSB10), mRNA. /FEA=mRNA /GEN=TMSB10 /PROD=thymosin, beta 10 /DB_XREF=gi:10863894 /UG=Hs.76293 thymosin, beta 10 /FL=gb:NM_021103.1 gb:M92381.1 gb:M20259.1 NM_021103 thymosin beta 10 TMSB10 9168 NM_021103 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042989 // sequestering of actin monomers // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 217734_s_at NM_018031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018031.2 /DEF=Homo sapiens WD repeat domain 6 (WDR6), mRNA. /FEA=mRNA /GEN=WDR6 /PROD=WD repeat domain 6 /DB_XREF=gi:11072092 /UG=Hs.8737 WD repeat domain 6 /FL=gb:NM_018031.2 gb:AF099100.1 NM_018031 WD repeat domain 6 WDR6 11180 NM_018031 /// XM_005264837 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217735_s_at AW007368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007368 /FEA=EST /DB_XREF=gi:5856146 /DB_XREF=est:ws51f08.x1 /CLONE=IMAGE:2500743 /UG=Hs.258730 heme-regulated initiation factor 2-alpha kinase /FL=gb:NM_014413.2 gb:AL136563.1 gb:AF147094.1 gb:AF255050.1 gb:AF116634.1 gb:AF183414.1 AW007368 eukaryotic translation initiation factor 2-alpha kinase 1 EIF2AK1 27102 NM_001134335 /// NM_014413 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 217736_s_at NM_014413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014413.2 /DEF=Homo sapiens heme-regulated initiation factor 2-alpha kinase (HRI), mRNA. /FEA=mRNA /GEN=HRI /PROD=heme-regulated initiation factor 2-alpha kinase /DB_XREF=gi:11125767 /UG=Hs.258730 heme-regulated initiation factor 2-alpha kinase /FL=gb:NM_014413.2 gb:AL136563.1 gb:AF147094.1 gb:AF255050.1 gb:AF116634.1 gb:AF183414.1 NM_014413 eukaryotic translation initiation factor 2-alpha kinase 1 EIF2AK1 27102 NM_001134335 /// NM_014413 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 217737_x_at NM_016407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016407.1 /DEF=Homo sapiens hypothetical protein (HSPC164), mRNA. /FEA=mRNA /GEN=HSPC164 /PROD=hypothetical protein /DB_XREF=gi:7705482 /UG=Hs.182281 hypothetical protein /FL=gb:BC003359.1 gb:AF212244.1 gb:AF117231.1 gb:AF161513.1 gb:AF161518.1 gb:NM_016407.1 NM_016407 replication termination factor 2 domain containing 1 RTFDC1 51507 NM_001283035 /// NM_001283036 /// NM_001283037 /// NM_016407 217738_at BF575514 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF575514 /FEA=EST /DB_XREF=gi:11649318 /DB_XREF=est:602133090F1 /CLONE=IMAGE:4288079 /UG=Hs.239138 pre-B-cell colony-enhancing factor /FL=gb:U02020.1 gb:NM_005746.1 BF575514 nicotinamide phosphoribosyltransferase NAMPT 10135 NM_005746 /// NM_182790 /// XM_005250100 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006769 // nicotinamide metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0060612 // adipose tissue development // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from electronic annotation /// 0004516 // nicotinate phosphoribosyltransferase activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047280 // nicotinamide phosphoribosyltransferase activity // inferred from electronic annotation 217739_s_at NM_005746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005746.1 /DEF=Homo sapiens pre-B-cell colony-enhancing factor (PBEF), mRNA. /FEA=mRNA /GEN=PBEF /PROD=pre-B-cell colony-enhancing factor /DB_XREF=gi:5031976 /UG=Hs.239138 pre-B-cell colony-enhancing factor /FL=gb:U02020.1 gb:NM_005746.1 NM_005746 nicotinamide phosphoribosyltransferase NAMPT 10135 NM_005746 /// NM_182790 /// XM_005250100 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006769 // nicotinamide metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0060612 // adipose tissue development // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from electronic annotation /// 0004516 // nicotinate phosphoribosyltransferase activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047280 // nicotinamide phosphoribosyltransferase activity // inferred from electronic annotation 217740_x_at NM_000972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000972.1 /DEF=Homo sapiens ribosomal protein L7a (RPL7A), mRNA. /FEA=mRNA /GEN=RPL7A /PROD=ribosomal protein L7a /DB_XREF=gi:4506660 /UG=Hs.99858 ribosomal protein L7a /FL=gb:BC005128.1 gb:M36072.1 gb:NM_000972.1 NM_000972 ribosomal protein L7a /// small nucleolar RNA, C/D box 24 /// small nucleolar RNA, C/D box 36A /// small nucleolar RNA, C/D box 36B RPL7A /// SNORD24 /// SNORD36A /// SNORD36B 6130 /// 26814 /// 26815 /// 26820 NM_000972 /// NR_000017 /// NR_002447 /// NR_002448 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042788 // polysomal ribosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217741_s_at AW471220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW471220 /FEA=EST /DB_XREF=gi:7041326 /DB_XREF=est:xv13g08.x1 /CLONE=IMAGE:2813054 /UG=Hs.3776 zinc finger protein 216 /FL=gb:AF062346.1 gb:NM_006007.1 AW471220 zinc finger, AN1-type domain 5 ZFAND5 7763 NM_001102420 /// NM_001102421 /// NM_001278243 /// NM_001278244 /// NM_001278245 /// NM_006007 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217742_s_at NM_016628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016628.1 /DEF=Homo sapiens hypothetical protein (LOC51322), mRNA. /FEA=mRNA /GEN=LOC51322 /PROD=hypothetical protein /DB_XREF=gi:7706169 /UG=Hs.70333 hypothetical protein /FL=gb:BC004258.1 gb:AF208858.1 gb:NM_016628.1 NM_016628 WW domain containing adaptor with coiled-coil WAC 51322 NM_016628 /// NM_100264 /// NM_100486 /// NR_024557 /// XM_005252454 /// XM_005252457 /// XM_005252459 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0010390 // histone monoubiquitination // inferred from mutant phenotype /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0044783 // G1 DNA damage checkpoint // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0071894 // histone H2B conserved C-terminal lysine ubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 217743_s_at NM_018247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018247.1 /DEF=Homo sapiens hypothetical protein FLJ10856 (FLJ10856), mRNA. /FEA=mRNA /GEN=FLJ10856 /PROD=hypothetical protein FLJ10856 /DB_XREF=gi:8922719 /UG=Hs.108530 hypothetical protein FLJ10856 /FL=gb:NM_018247.1 NM_018247 transmembrane protein 30A TMEM30A 55754 NM_001143958 /// NM_018247 0006810 // transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred from direct assay /// 0006869 // lipid transport // inferred from electronic annotation /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0045332 // phospholipid translocation // inferred from direct assay /// 0070863 // positive regulation of protein exit from endoplasmic reticulum // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217744_s_at NM_022121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022121.1 /DEF=Homo sapiens p53-induced protein PIGPC1 (PIGPC1), mRNA. /FEA=mRNA /GEN=PIGPC1 /PROD=p53-induced protein PIGPC1 /DB_XREF=gi:11545842 /UG=Hs.303125 p53-induced protein PIGPC1 /FL=gb:AF317550.1 gb:NM_022121.1 NM_022121 PERP, TP53 apoptosis effector PERP 64065 NM_022121 0002934 // desmosome organization // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097186 // amelogenesis // inferred from electronic annotation /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030057 // desmosome // inferred from electronic annotation 217745_s_at NM_025146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025146.1 /DEF=Homo sapiens hypothetical protein FLJ13194 (FLJ13194), mRNA. /FEA=mRNA /GEN=FLJ13194 /PROD=hypothetical protein FLJ13194 /DB_XREF=gi:13376734 /UG=Hs.288932 hypothetical protein FLJ13194 /FL=gb:NM_025146.1 NM_025146 N(alpha)-acetyltransferase 50, NatE catalytic subunit NAA50 80218 NM_025146 /// XM_005247794 0006474 // N-terminal protein amino acid acetylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0071962 // mitotic sister chromatid cohesion, centromeric // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0031415 // NatA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0052858 // peptidyl-lysine N-acetyltransferase activity // inferred from direct assay 217746_s_at NM_013374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013374.1 /DEF=Homo sapiens programmed cell death 6-interacting protein (PDCD6IP), mRNA. /FEA=mRNA /GEN=PDCD6IP /PROD=programmed cell death 6-interacting protein /DB_XREF=gi:7019486 /UG=Hs.9663 programmed cell death 6-interacting protein /FL=gb:AF349951.1 gb:AF151793.1 gb:NM_013374.1 NM_013374 programmed cell death 6 interacting protein PDCD6IP 10015 NM_001162429 /// NM_001256192 /// NM_013374 /// NR_027867 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0001772 // immunological synapse // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 217747_s_at NM_001013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001013.1 /DEF=Homo sapiens ribosomal protein S9 (RPS9), mRNA. /FEA=mRNA /GEN=RPS9 /PROD=ribosomal protein S9 /DB_XREF=gi:4506744 /UG=Hs.180920 ribosomal protein S9 /FL=gb:BC000802.1 gb:NM_001013.1 gb:U14971.1 NM_001013 ribosomal protein S9 RPS9 6203 NM_001013 /// XM_005259135 /// XM_005259136 /// XM_005277084 /// XM_005277085 /// XM_005277274 /// XM_005277315 /// XM_005277316 /// XM_005278287 /// XM_005278288 /// XM_006725876 /// XM_006725877 /// XM_006725964 /// XM_006725965 /// XM_006726063 /// XM_006726064 /// XM_006726164 /// XM_006726165 /// XM_006726201 /// XM_006726202 /// XR_243946 /// XR_243947 /// XR_254260 /// XR_254311 /// XR_254323 /// XR_254324 /// XR_254517 /// XR_254518 /// XR_430207 /// XR_430911 /// XR_430953 /// XR_430986 /// XR_430987 /// XR_430988 /// XR_431006 /// XR_431007 /// XR_431008 /// XR_431025 /// XR_431026 /// XR_431027 /// XR_431056 /// XR_431057 /// XR_431058 /// XR_431067 /// XR_431068 /// XR_431069 /// XR_431090 /// XR_431099 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1901741 // positive regulation of myoblast fusion // inferred from electronic annotation /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 217748_at NM_015999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015999.1 /DEF=Homo sapiens CGI-45 protein (LOC51094), mRNA. /FEA=mRNA /GEN=LOC51094 /PROD=CGI-45 protein /DB_XREF=gi:7705760 /UG=Hs.5298 CGI-45 protein /FL=gb:AF151803.1 gb:NM_015999.1 NM_015999 adiponectin receptor 1 ADIPOR1 51094 NM_001290553 /// NM_001290557 /// NM_001290629 /// NM_015999 /// NR_046083 /// XM_006711360 /// XM_006711361 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0019395 // fatty acid oxidation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0033210 // leptin-mediated signaling pathway // inferred from electronic annotation /// 0033211 // adiponectin-activated signaling pathway // not recorded /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004872 // receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042562 // hormone binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 217749_at NM_016128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016128.1 /DEF=Homo sapiens coat protein gamma-cop (LOC51137), mRNA. /FEA=mRNA /GEN=LOC51137 /PROD=coat protein gamma-cop /DB_XREF=gi:11559928 /UG=Hs.102950 coat protein gamma-cop /FL=gb:AB047846.1 gb:NM_016128.1 gb:AF100756.1 NM_016128 coatomer protein complex, subunit gamma 1 COPG1 22820 NM_016128 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0051683 // establishment of Golgi localization // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0072384 // organelle transport along microtubule // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217750_s_at NM_023079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023079.1 /DEF=Homo sapiens hypothetical protein FLJ13855 (FLJ13855), mRNA. /FEA=mRNA /GEN=FLJ13855 /PROD=hypothetical protein FLJ13855 /DB_XREF=gi:12751494 /UG=Hs.168232 hypothetical protein FLJ13855 /FL=gb:NM_023079.1 NM_023079 ubiquitin-conjugating enzyme E2Z UBE2Z 65264 NM_023079 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217751_at NM_015917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015917.1 /DEF=Homo sapiens glutathione S-transferase subunit 13 homolog (LOC51064), mRNA. /FEA=mRNA /GEN=LOC51064 /PROD=glutathione S-transferase subunit 13 homolog /DB_XREF=gi:7705703 /UG=Hs.279952 glutathione S-transferase subunit 13 homolog /FL=gb:AL136938.1 gb:BC001231.1 gb:AF070657.1 gb:AF068287.1 gb:NM_015917.1 NM_015917 glutathione S-transferase kappa 1 GSTK1 373156 NM_001143679 /// NM_001143680 /// NM_001143681 /// NM_015917 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 217752_s_at NM_018235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018235.1 /DEF=Homo sapiens hypothetical protein FLJ10830 (FLJ10830), mRNA. /FEA=mRNA /GEN=FLJ10830 /PROD=hypothetical protein FLJ10830 /DB_XREF=gi:8922698 /UG=Hs.273230 hypothetical protein FLJ10830 /FL=gb:BC001375.1 gb:BC003176.1 gb:NM_018235.1 NM_018235 CNDP dipeptidase 2 (metallopeptidase M20 family) CNDP2 55748 NM_001168499 /// NM_018235 /// XM_005266728 /// XM_006722502 /// XM_006722503 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0034701 // tripeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217753_s_at NM_001029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001029.1 /DEF=Homo sapiens ribosomal protein S26 (RPS26), mRNA. /FEA=mRNA /GEN=RPS26 /PROD=ribosomal protein S26 /DB_XREF=gi:4506708 /UG=Hs.299465 ribosomal protein S26 /FL=gb:BC002604.1 gb:NM_001029.1 NM_001029 40S ribosomal protein S26-like /// 40S ribosomal protein S26-like /// ribosomal protein S26 /// ribosomal protein S26 pseudogene 11 LOC100996747 /// LOC101929876 /// RPS26 /// RPS26P11 6231 /// 441502 /// 100996747 /// 101929876 NM_001029 /// NR_002309 /// XM_003846538 /// XM_005276684 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217754_at NM_019082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019082.1 /DEF=Homo sapiens putative nucleolar RNA helicase (NOH61), mRNA. /FEA=mRNA /GEN=NOH61 /PROD=putative nucleolar RNA helicase /DB_XREF=gi:9506930 /UG=Hs.10098 putative nucleolar RNA helicase /FL=gb:AF247666.1 gb:AL136700.1 gb:BC001235.1 gb:NM_019082.1 NM_019082 DEAD (Asp-Glu-Ala-Asp) box helicase 56 DDX56 54606 NM_001257189 /// NM_019082 0006200 // ATP catabolic process // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217755_at NM_016185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016185.1 /DEF=Homo sapiens hematological and neurological expressed 1 (HN1), mRNA. /FEA=mRNA /GEN=HN1 /PROD=hematological and neurological expressed 1 /DB_XREF=gi:7705876 /UG=Hs.109706 hematological and neurological expressed 1 /FL=gb:AF060925.1 gb:BC001420.1 gb:AF177862.1 gb:NM_016185.1 NM_016185 hematological and neurological expressed 1 HN1 51155 NM_001002032 /// NM_001002033 /// NM_001288609 /// NM_001288610 /// NM_001288611 /// NM_016185 /// NR_109933 /// XM_006721931 0005634 // nucleus // inferred from electronic annotation 217756_x_at NM_005770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005770.1 /DEF=Homo sapiens small EDRK-rich factor 2 (SERF2), mRNA. /FEA=mRNA /GEN=SERF2 /PROD=small EDRK-rich factor 2 /DB_XREF=gi:5032084 /UG=Hs.323806 small EDRK-rich factor 2 /FL=gb:AF320073.1 gb:AF073298.1 gb:NM_005770.1 NM_005770 huntingtin interacting protein K /// microRNA 1282 /// small EDRK-rich factor 2 HYPK /// MIR1282 /// SERF2 10169 /// 25764 /// 100302254 NM_001018108 /// NM_001199875 /// NM_001199876 /// NM_001199877 /// NM_001199878 /// NM_001199885 /// NM_005770 /// NM_016400 /// NR_031695 /// NR_037672 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217757_at NM_000014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000014.3 /DEF=Homo sapiens alpha-2-macroglobulin (A2M), mRNA. /FEA=mRNA /GEN=A2M /PROD=alpha 2 macroglobulin precursor /DB_XREF=gi:6226959 /UG=Hs.74561 alpha-2-macroglobulin /FL=gb:M11313.1 gb:NM_000014.3 NM_000014 alpha-2-macroglobulin A2M 2 NM_000014 /// XM_006719056 0001869 // negative regulation of complement activation, lectin pathway // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019959 // interleukin-8 binding // inferred from physical interaction /// 0019966 // interleukin-1 binding // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0043120 // tumor necrosis factor binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 217758_s_at NM_020123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020123.1 /DEF=Homo sapiens endomembrane protein emp70 precursor isolog (LOC56889), mRNA. /FEA=mRNA /GEN=LOC56889 /PROD=endomembrane protein emp70 precursor isolog /DB_XREF=gi:10047129 /UG=Hs.8203 endomembrane protein emp70 precursor isolog /FL=gb:NM_020123.1 gb:AF160213.1 gb:AF269150.1 NM_020123 transmembrane 9 superfamily member 3 TM9SF3 56889 NM_020123 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217759_at BF431488 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431488 /FEA=EST /DB_XREF=gi:11443602 /DB_XREF=est:7o14f01.x1 /CLONE=IMAGE:3574033 /UG=Hs.14512 DIPB protein /FL=gb:NM_017583.1 BF431488 tripartite motif containing 44 TRIM44 54765 NM_017583 /// XM_006718254 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217760_at AA176780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA176780 /FEA=EST /DB_XREF=gi:1757929 /DB_XREF=est:zp32a10.s1 /CLONE=IMAGE:611130 /UG=Hs.14512 DIPB protein /FL=gb:NM_017583.1 AA176780 tripartite motif containing 44 TRIM44 54765 NM_017583 /// XM_006718254 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217761_at NM_018269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018269.1 /DEF=Homo sapiens hypothetical protein FLJ10913 (FLJ10913), mRNA. /FEA=mRNA /GEN=FLJ10913 /PROD=hypothetical protein FLJ10913 /DB_XREF=gi:8922761 /UG=Hs.64322 hypothetical protein FLJ10913 /FL=gb:BC001467.1 gb:NM_018269.1 NM_018269 acireductone dioxygenase 1 ADI1 55256 NM_018269 /// XM_005264696 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from direct assay /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010309 // acireductone dioxygenase [iron(II)-requiring] activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 217762_s_at BE789881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE789881 /FEA=EST /DB_XREF=gi:10211079 /DB_XREF=est:601476750F1 /CLONE=IMAGE:3879493 /UG=Hs.223025 RAB31, member RAS oncogene family /FL=gb:AF234995.1 gb:BC001148.1 gb:U59877.1 gb:U57091.1 gb:NM_006868.1 gb:AF183421.1 BE789881 RAB31, member RAS oncogene family RAB31 11031 NM_006868 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0090382 // phagosome maturation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 217763_s_at NM_006868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006868.1 /DEF=Homo sapiens RAB31, member RAS oncogene family (RAB31), mRNA. /FEA=mRNA /GEN=RAB31 /PROD=RAB31, member RAS oncogene family /DB_XREF=gi:5803130 /UG=Hs.223025 RAB31, member RAS oncogene family /FL=gb:AF234995.1 gb:BC001148.1 gb:U59877.1 gb:U57091.1 gb:NM_006868.1 gb:AF183421.1 NM_006868 RAB31, member RAS oncogene family RAB31 11031 NM_006868 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0090382 // phagosome maturation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 217764_s_at AF183421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF183421.1 /DEF=Homo sapiens small GTP-binding protein rab22b mRNA, complete cds. /FEA=mRNA /PROD=small GTP-binding protein rab22b /DB_XREF=gi:9963780 /UG=Hs.223025 RAB31, member RAS oncogene family /FL=gb:AF234995.1 gb:BC001148.1 gb:U59877.1 gb:U57091.1 gb:NM_006868.1 gb:AF183421.1 AF183421 RAB31, member RAS oncogene family RAB31 11031 NM_006868 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0090382 // phagosome maturation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 217765_at NM_013392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013392.1 /DEF=Homo sapiens nuclear receptor binding protein (NRBP), mRNA. /FEA=mRNA /GEN=NRBP /PROD=nuclear receptor binding protein /DB_XREF=gi:7019332 /UG=Hs.272736 nuclear receptor binding protein /FL=gb:BC001221.1 gb:AF113249.1 gb:NM_013392.1 NM_013392 nuclear receptor binding protein 1 NRBP1 29959 NM_013392 /// XM_005264274 /// XM_006711999 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 217766_s_at NM_014313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014313.1 /DEF=Homo sapiens small membrane protein 1 (SMP1), mRNA. /FEA=mRNA /GEN=SMP1 /PROD=small membrane protein 1 /DB_XREF=gi:7657594 /UG=Hs.107979 small membrane protein 1 /FL=gb:AL136627.1 gb:AF081282.1 gb:NM_014313.1 NM_014313 transmembrane protein 50A TMEM50A 23585 NM_014313 /// XM_005245817 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217767_at NM_000064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000064.1 /DEF=Homo sapiens complement component 3 (C3), mRNA. /FEA=mRNA /GEN=C3 /PROD=complement component 3 precursor /DB_XREF=gi:4557384 /UG=Hs.284394 complement component 3 /FL=gb:K02765.1 gb:NM_000064.1 NM_000064 complement component 3 C3 718 NM_000064 0001798 // positive regulation of type IIa hypersensitivity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001970 // positive regulation of activation of membrane attack complex // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006956 // complement activation // inferred from mutant phenotype /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010828 // positive regulation of glucose transport // inferred from direct assay /// 0010866 // regulation of triglyceride biosynthetic process // inferred from direct assay /// 0010884 // positive regulation of lipid storage // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 2000427 // positive regulation of apoptotic cell clearance // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031715 // C5L2 anaphylatoxin chemotactic receptor binding // inferred from direct assay 217768_at NM_016039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016039.1 /DEF=Homo sapiens CGI-99 protein (LOC51637), mRNA. /FEA=mRNA /GEN=LOC51637 /PROD=CGI-99 protein /DB_XREF=gi:7706321 /UG=Hs.110803 CGI-99 protein /FL=gb:BC001722.1 gb:AF151857.1 gb:AF100755.1 gb:NM_016039.1 NM_016039 chromosome 14 open reading frame 166 C14orf166 51637 NM_016039 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0072669 // tRNA-splicing ligase complex // inferred from direct assay 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217769_s_at NM_015932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015932.1 /DEF=Homo sapiens hypothetical protein (HSPC014), mRNA. /FEA=mRNA /GEN=HSPC014 /PROD=hypothetical protein /DB_XREF=gi:7705428 /UG=Hs.279813 hypothetical protein /FL=gb:AF275807.1 gb:BC003390.1 gb:AF077200.1 gb:AF125097.1 gb:NM_015932.1 NM_015932 proteasome maturation protein POMP 51371 NM_015932 0043248 // proteasome assembly // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217770_at NM_015937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015937.1 /DEF=Homo sapiens CGI-06 protein (LOC51604), mRNA. /FEA=mRNA /GEN=LOC51604 /PROD=CGI-06 protein /DB_XREF=gi:7706257 /UG=Hs.84038 CGI-06 protein /FL=gb:AF132940.1 gb:NM_015937.1 NM_015937 phosphatidylinositol glycan anchor biosynthesis, class T PIGT 51604 NM_001184728 /// NM_001184729 /// NM_001184730 /// NM_015937 /// NR_047691 /// NR_047692 /// NR_047693 /// NR_047694 /// NR_047695 /// XM_005260430 /// XM_005260432 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0042765 // GPI-anchor transamidase complex // traceable author statement 0003923 // GPI-anchor transamidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217771_at NM_016548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016548.1 /DEF=Homo sapiens golgi membrane protein GP73 (LOC51280), mRNA. /FEA=mRNA /GEN=LOC51280 /PROD=golgi membrane protein GP73 /DB_XREF=gi:7706084 /UG=Hs.182793 golgi membrane protein GP73 /FL=gb:BC001740.1 gb:AF236056.1 gb:NM_016548.1 NM_016548 golgi membrane protein 1 GOLM1 51280 NM_001099268 /// NM_016548 /// NM_177937 0006997 // nucleus organization // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217772_s_at NM_014342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014342.1 /DEF=Homo sapiens mitochondrial carrier homolog 2 (MTCH2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTCH2 /PROD=mitochondrial carrier homolog 2 /DB_XREF=gi:7657346 /UG=Hs.279609 mitochondrial carrier homolog 2 /FL=gb:BC000875.1 gb:AF085361.1 gb:AF176008.1 gb:NM_014342.1 NM_014342 mitochondrial carrier 2 MTCH2 23788 NM_014342 /// XM_005252841 /// XM_006718172 /// XM_006718173 0006810 // transport // inferred from electronic annotation /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 217773_s_at NM_002489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002489.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9kD, MLRQ) (NDUFA4), mRNA. /FEA=mRNA /GEN=NDUFA4 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 4 (9kD, MLRQ) /DB_XREF=gi:4505356 /UG=Hs.50098 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9kD, MLRQ) /FL=gb:U94586.1 gb:NM_002489.1 gb:AF201077.1 NM_002489 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa NDUFA4 4697 NM_002489 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005751 // mitochondrial respiratory chain complex IV // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0032403 // protein complex binding // inferred from direct assay 217774_s_at NM_016404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016404.1 /DEF=Homo sapiens hypothetical protein (HSPC152), mRNA. /FEA=mRNA /GEN=HSPC152 /PROD=hypothetical protein /DB_XREF=gi:7705476 /UG=Hs.79259 hypothetical protein /FL=gb:AF110774.1 gb:AF161501.1 gb:NM_016404.1 gb:AF229068.1 NM_016404 tRNA methyltransferase 11-2 homolog (S. cerevisiae) TRMT112 51504 NM_001286082 /// NM_001286084 /// NM_016404 0018364 // peptidyl-glutamine methylation // inferred from direct assay 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008276 // protein methyltransferase activity // inferred from direct assay 217775_s_at NM_016026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016026.1 /DEF=Homo sapiens CGI-82 protein (LOC51109), mRNA. /FEA=mRNA /GEN=LOC51109 /PROD=CGI-82 protein /DB_XREF=gi:7705790 /UG=Hs.179817 CGI-82 protein /FL=gb:BC000112.1 gb:AF151840.1 gb:NM_016026.1 gb:AF167438.1 NM_016026 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) RDH11 51109 NM_001252650 /// NM_016026 0001523 // retinoid metabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016062 // adaptation of rhodopsin mediated signaling // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from sequence or structural similarity /// 0042574 // retinal metabolic process // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from direct assay 217776_at AF167438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF167438.1 /DEF=Homo sapiens androgen-regulated short-chain dehydrogenasereductase 1 (ARSDR1) mRNA, complete cds. /FEA=mRNA /GEN=ARSDR1 /PROD=androgen-regulated short-chaindehydrogenasereductase 1 /DB_XREF=gi:9622123 /UG=Hs.179817 CGI-82 protein /FL=gb:BC000112.1 gb:AF151840.1 gb:NM_016026.1 gb:AF167438.1 AF167438 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) RDH11 51109 NM_001252650 /// NM_016026 0001523 // retinoid metabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016062 // adaptation of rhodopsin mediated signaling // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from sequence or structural similarity /// 0042574 // retinal metabolic process // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from direct assay 217777_s_at NM_016395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016395.1 /DEF=Homo sapiens butyrate-induced transcript 1 (HSPC121), mRNA. /FEA=mRNA /GEN=HSPC121 /PROD=butyrate-induced transcript 1 /DB_XREF=gi:7705458 /UG=Hs.260622 butyrate-induced transcript 1 /FL=gb:AF161470.1 gb:NM_016395.1 NM_016395 protein tyrosine phosphatase-like A domain containing 1 PTPLAD1 51495 NM_016395 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation 217778_at NM_014437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014437.1 /DEF=Homo sapiens zinciron regulated transporter-like (ZIRTL), mRNA. /FEA=mRNA /GEN=ZIRTL /PROD=zinciron regulated transporter-like /DB_XREF=gi:7657700 /UG=Hs.7854 zinciron regulated transporter-like /FL=gb:BC002563.1 gb:BC003152.1 gb:AF132942.1 gb:AF151829.1 gb:NM_014437.1 NM_014437 solute carrier family 39 (zinc transporter), member 1 SLC39A1 27173 NM_001271957 /// NM_001271958 /// NM_001271959 /// NM_001271960 /// NM_001271961 /// NM_014437 /// XM_006711276 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005385 // zinc ion transmembrane transporter activity // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // traceable author statement /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 217779_s_at NM_017761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017761.1 /DEF=Homo sapiens hypothetical protein FLJ20312 (FLJ20312), mRNA. /FEA=mRNA /GEN=FLJ20312 /PROD=hypothetical protein FLJ20312 /DB_XREF=gi:8923294 /UG=Hs.7862 hypothetical protein FLJ20312 /FL=gb:BC001959.1 gb:AF151042.1 gb:NM_017761.1 NM_017761 proline-rich nuclear receptor coactivator 2 PNRC2 55629 NM_017761 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0031087 // deadenylation-independent decapping of nuclear-transcribed mRNA // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction 217780_at NM_016145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016145.1 /DEF=Homo sapiens PTD008 protein (PTD008), mRNA. /FEA=mRNA /GEN=PTD008 /PROD=PTD008 protein /DB_XREF=gi:7706664 /UG=Hs.108969 PTD008 protein /FL=gb:AF059620.1 gb:AF151898.1 gb:AF078861.1 gb:NM_016145.1 NM_016145 WD repeat domain 83 opposite strand WDR83OS 51398 NM_016145 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217781_s_at NM_022473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022473.1 /DEF=Homo sapiens zinc finger protein 106 (ZFP106), mRNA. /FEA=mRNA /GEN=ZFP106 /PROD=zinc finger protein 106 /DB_XREF=gi:11968022 /UG=Hs.15220 zinc finger protein 106 /FL=gb:AF205632.1 gb:NM_022473.1 NM_022473 zinc finger protein 106 ZNF106 64397 NM_001284306 /// NM_001284307 /// NM_022473 /// XM_005254591 /// XM_005254592 0008286 // insulin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001515 // opioid peptide activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217782_s_at NM_004127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004127.3 /DEF=Homo sapiens G protein pathway suppressor 1 (GPS1), mRNA. /FEA=mRNA /GEN=GPS1 /PROD=G protein pathway suppressor 1 /DB_XREF=gi:13435380 /UG=Hs.268530 G protein pathway suppressor 1 /FL=gb:BC000155.1 gb:NM_004127.3 gb:U20285.2 NM_004127 G protein pathway suppressor 1 GPS1 2873 NM_004127 /// NM_212492 /// XM_005256350 /// XM_005256351 /// XM_005256352 /// XM_005256353 /// XM_005256354 /// XM_005256355 /// XM_005256356 /// XM_005256357 /// XM_005256358 /// XM_005256359 /// XM_005256360 /// XM_005256362 /// XM_005256363 0000188 // inactivation of MAPK activity // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay 0005095 // GTPase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217783_s_at NM_016061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016061.1 /DEF=Homo sapiens CGI-127 protein (LOC51646), mRNA. /FEA=mRNA /GEN=LOC51646 /PROD=CGI-127 protein /DB_XREF=gi:7706340 /UG=Hs.184542 CGI-127 protein /FL=gb:BC000836.1 gb:AF151885.1 gb:NM_016061.1 NM_016061 yippee-like 5 (Drosophila) YPEL5 51646 NM_001127399 /// NM_001127400 /// NM_001127401 /// NM_016061 217784_at BE384482 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE384482 /FEA=EST /DB_XREF=gi:9329847 /DB_XREF=est:601277836F1 /CLONE=IMAGE:3618848 /UG=Hs.296244 SNARE protein /FL=gb:U95735.1 gb:NM_006555.1 BE384482 YKT6 v-SNARE homolog (S. cerevisiae) YKT6 10652 NM_006555 /// XM_005249582 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0006903 // vesicle targeting // inferred from direct assay /// 0006904 // vesicle docking involved in exocytosis // inferred from direct assay /// 0006906 // vesicle fusion // not recorded /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0031201 // SNARE complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from direct assay 217785_s_at NM_006555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006555.1 /DEF=Homo sapiens SNARE protein (YKT6), mRNA. /FEA=mRNA /GEN=YKT6 /PROD=SNARE protein /DB_XREF=gi:5730119 /UG=Hs.296244 SNARE protein /FL=gb:U95735.1 gb:NM_006555.1 NM_006555 YKT6 v-SNARE homolog (S. cerevisiae) YKT6 10652 NM_006555 /// XM_005249582 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0006903 // vesicle targeting // inferred from direct assay /// 0006904 // vesicle docking involved in exocytosis // inferred from direct assay /// 0006906 // vesicle fusion // not recorded /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0031201 // SNARE complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from direct assay 217786_at NM_006109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006109.1 /DEF=Homo sapiens skb1 (S. pombe) homolog (SKB1), mRNA. /FEA=mRNA /GEN=SKB1 /PROD=skb1 (S. pombe) homolog /DB_XREF=gi:5174682 /UG=Hs.12912 skb1 (S. pombe) homolog /FL=gb:AF015913.1 gb:NM_006109.1 gb:AF167572.1 NM_006109 protein arginine methyltransferase 5 PRMT5 10419 NM_001039619 /// NM_001282953 /// NM_001282954 /// NM_001282955 /// NM_001282956 /// NM_006109 /// XR_429287 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000387 // spliceosomal snRNP assembly // inferred from mutant phenotype /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006479 // protein methylation // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018216 // peptidyl-arginine methylation // inferred from mutant phenotype /// 0019918 // peptidyl-arginine methylation, to symmetrical-dimethyl arginine // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034660 // ncRNA metabolic process // traceable author statement /// 0035246 // peptidyl-arginine N-methylation // inferred from direct assay /// 0042118 // endothelial cell activation // inferred from mutant phenotype /// 0043985 // histone H4-R3 methylation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from direct assay /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0035243 // protein-arginine omega-N symmetric methyltransferase activity // inferred from mutant phenotype /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction 217787_s_at AL525086 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL525086 /FEA=EST /DB_XREF=gi:12788579 /DB_XREF=est:AL525086 /CLONE=CS0DC005YC04 (3 prime) /UG=Hs.130181 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) /FL=gb:NM_004481.2 AL525086 polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 2590 NM_001291866 /// NM_004481 /// NR_120373 0002378 // immunoglobulin biosynthetic process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217788_s_at NM_004481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004481.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2), mRNA. /FEA=mRNA /GEN=GALNT2 /PROD=polypeptide N-acetylgalactosaminyltransferase 2 /DB_XREF=gi:9945385 /UG=Hs.130181 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) /FL=gb:NM_004481.2 NM_004481 polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 2590 NM_001291866 /// NM_004481 /// NR_120373 0002378 // immunoglobulin biosynthetic process // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217789_at NM_021249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021249.1 /DEF=Homo sapiens sorting nexin 6 (SNX6), mRNA. /FEA=mRNA /GEN=SNX6 /PROD=sorting nexin 6 /DB_XREF=gi:13027619 /UG=Hs.284291 sorting nexin 6 /FL=gb:BC001798.1 gb:NM_021249.1 gb:AF121856.1 NM_021249 sorting nexin 6 SNX6 58533 NM_021249 /// NM_152233 /// XM_006720224 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006886 // intracellular protein transport // non-traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded /// 0042803 // protein homodimerization activity // inferred from physical interaction 217790_s_at NM_007107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007107.1 /DEF=Homo sapiens signal sequence receptor, gamma (translocon-associated protein gamma) (SSR3), mRNA. /FEA=mRNA /GEN=SSR3 /PROD=signal sequence receptor, gamma(translocon-associated protein gamma) /DB_XREF=gi:6005883 /UG=Hs.28707 signal sequence receptor, gamma (translocon-associated protein gamma) /FL=gb:AF110647.1 gb:NM_007107.1 NM_007107 signal sequence receptor, gamma (translocon-associated protein gamma) SSR3 6747 NM_007107 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005784 // Sec61 translocon complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 217791_s_at NM_002860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002860.1 /DEF=Homo sapiens pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) (PYCS), mRNA. /FEA=mRNA /GEN=PYCS /PROD=pyrroline-5-carboxylate synthetase (glutamategamma-semialdehyde synthetase) /DB_XREF=gi:4506348 /UG=Hs.114366 pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) /FL=gb:U68758.1 gb:U76542.1 gb:NM_002860.1 NM_002860 aldehyde dehydrogenase 18 family, member A1 ALDH18A1 5832 NM_001017423 /// NM_002860 /// XM_006717933 0006536 // glutamate metabolic process // inferred from mutant phenotype /// 0006561 // proline biosynthetic process // inferred from mutant phenotype /// 0006592 // ornithine biosynthetic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019240 // citrulline biosynthetic process // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004349 // glutamate 5-kinase activity // inferred from direct assay /// 0004350 // glutamate-5-semialdehyde dehydrogenase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217792_at NM_014426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014426.1 /DEF=Homo sapiens sorting nexin 5 (SNX5), mRNA. /FEA=mRNA /GEN=SNX5 /PROD=sorting nexin 5 /DB_XREF=gi:7657598 /UG=Hs.13794 sorting nexin 5 /FL=gb:BC000100.1 gb:AF121855.1 gb:NM_014426.1 NM_014426 sorting nexin 5 SNX5 27131 NM_001282454 /// NM_014426 /// NM_152227 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031313 // extrinsic component of endosome membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070685 // macropinocytic cup // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity 217793_at AL575337 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL575337 /FEA=EST /DB_XREF=gi:12936406 /DB_XREF=est:AL575337 /CLONE=CS0DI061YI16 (3 prime) /UG=Hs.239018 RAB11B, member RAS oncogene family /FL=gb:NM_004218.1 AL575337 RAB11B, member RAS oncogene family RAB11B 9230 NM_004218 0001881 // receptor recycling // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0033572 // transferrin transport // inferred from sequence or structural similarity /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0044070 // regulation of anion transport // inferred from mutant phenotype /// 0045054 // constitutive secretory pathway // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0071468 // cellular response to acidity // inferred from direct assay /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype /// 2001135 // regulation of endocytic recycling // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 217794_at NM_018457 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018457.1 /DEF=Homo sapiens DKFZp564J157 protein (DKFZP564J157), mRNA. /FEA=mRNA /GEN=DKFZP564J157 /PROD=DKFZp564J157 protein /DB_XREF=gi:8922156 /UG=Hs.63042 DKFZp564J157 protein /FL=gb:AF217517.1 gb:NM_018457.1 NM_018457 proline rich 13 PRR13 54458 NM_001005354 /// NM_001005355 /// NM_018457 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 217795_s_at W74580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W74580 /FEA=EST /DB_XREF=gi:1384812 /DB_XREF=est:zd76g10.s1 /CLONE=IMAGE:346626 /UG=Hs.323193 hypothetical protein MGC3222 /FL=gb:AL136916.1 gb:BC003125.1 gb:NM_024334.1 W74580 transmembrane protein 43 TMEM43 79188 NM_024334 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217796_s_at NM_017921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017921.1 /DEF=Homo sapiens hypothetical protein FLJ20657 (FLJ20657), mRNA. /FEA=mRNA /GEN=FLJ20657 /PROD=hypothetical protein FLJ20657 /DB_XREF=gi:8923608 /UG=Hs.164256 hypothetical protein FLJ20657 /FL=gb:NM_017921.1 NM_017921 nuclear protein localization 4 homolog (S. cerevisiae) NPLOC4 55666 NM_017921 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217797_at NM_016406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016406.1 /DEF=Homo sapiens hypothetical protein (HSPC155), mRNA. /FEA=mRNA /GEN=HSPC155 /PROD=hypothetical protein /DB_XREF=gi:7705480 /UG=Hs.177507 hypothetical protein /FL=gb:BC005187.1 gb:AF151884.1 gb:AF161504.1 gb:NM_016406.1 NM_016406 ubiquitin-fold modifier conjugating enzyme 1 UFC1 51506 NM_016406 /// XM_005245254 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0071569 // protein ufmylation // inferred from direct assay /// 0071569 // protein ufmylation // inferred from mutant phenotype 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0071568 // UFM1 conjugating enzyme activity // inferred from direct assay 217798_at AI123426 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI123426 /FEA=EST /DB_XREF=gi:3539192 /DB_XREF=est:qa49c09.x1 /CLONE=IMAGE:1690096 /UG=Hs.239720 CCR4-NOT transcription complex, subunit 2 /FL=gb:AF113226.1 gb:AF180473.1 gb:NM_014515.1 AI123426 CCR4-NOT transcription complex, subunit 2 CNOT2 4848 NM_001199302 /// NM_001199303 /// NM_014515 /// NR_037615 /// XM_006719429 /// XM_006719430 /// XM_006719431 /// XM_006719432 /// XM_006719433 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // traceable author statement /// 0001226 // RNA polymerase II transcription corepressor binding // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 217799_x_at NM_003344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003344.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8) (UBE2H), mRNA. /FEA=mRNA /GEN=UBE2H /PROD=ubiquitin-conjugating enzyme E2H (homologous toyeast UBC8) /DB_XREF=gi:4507782 /UG=Hs.28505 ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8) /FL=gb:NM_003344.1 NM_003344 ubiquitin-conjugating enzyme E2H UBE2H 7328 NM_001202498 /// NM_003344 /// NM_182697 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217800_s_at NM_030571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030571.1 /DEF=Homo sapiens hypothetical protein MGC10924 similar to Nedd4 WW-binding protein 5 (MGC10924), mRNA. /FEA=mRNA /GEN=MGC10924 /PROD=hypothetical protein MGC10924 similar to Nedd4WW-binding protein 5 /DB_XREF=gi:13386479 /UG=Hs.9788 hypothetical protein MGC10924 similar to Nedd4 WW-binding protein 5 /FL=gb:BC004317.1 gb:NM_030571.1 NM_030571 Nedd4 family interacting protein 1 NDFIP1 80762 NM_030571 0002761 // regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // inferred from mutant phenotype /// 0032410 // negative regulation of transporter activity // inferred from mutant phenotype /// 0032713 // negative regulation of interleukin-4 production // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from electronic annotation /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0048294 // negative regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0048302 // regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051224 // negative regulation of protein transport // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from electronic annotation 217801_at NM_006886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006886.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (ATP5E), mRNA. /FEA=mRNA /GEN=ATP5E /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, epsilon subunit /DB_XREF=gi:5901895 /UG=Hs.177530 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit /FL=gb:BC001690.1 gb:BC003671.1 gb:AF077045.1 gb:NM_006886.1 gb:AF052955.1 NM_006886 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit ATP5E 514 NM_006886 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0015914 // phospholipid transport // /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // /// 0005759 // mitochondrial matrix // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation /// 1990050 // phosphatidic acid transporter activity // 217802_s_at NM_022731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022731.1 /DEF=Homo sapiens similar to rat nuclear ubiquitous casein kinase 2 (NUCKS), mRNA. /FEA=mRNA /GEN=NUCKS /PROD=similar to rat nuclear ubiquitous casein kinase2 /DB_XREF=gi:12232386 /UG=Hs.118064 similar to rat nuclear ubiquitous casein kinase 2 /FL=gb:NM_022731.1 gb:BC000805.1 NM_022731 nuclear casein kinase and cyclin-dependent kinase substrate 1 NUCKS1 64710 NM_022731 /// XM_005245453 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217803_at NM_022130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022130.1 /DEF=Homo sapiens Golgi protein (GPP34), mRNA. /FEA=mRNA /GEN=GPP34 /PROD=Golgi protein /DB_XREF=gi:11545858 /UG=Hs.18271 Golgi protein /FL=gb:NM_022130.1 NM_022130 golgi phosphoprotein 3 (coat-protein) GOLPH3 64083 NM_022130 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009101 // glycoprotein biosynthetic process // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from mutant phenotype /// 0010467 // gene expression // inferred from mutant phenotype /// 0010821 // regulation of mitochondrion organization // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045053 // protein retention in Golgi apparatus // inferred from mutant phenotype /// 0048194 // Golgi vesicle budding // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050901 // leukocyte tethering or rolling // inferred from mutant phenotype /// 0060352 // cell adhesion molecule production // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031985 // Golgi cisterna // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay 217804_s_at BC003086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003086.1 /DEF=Homo sapiens, hypothetical protein FLJ20011, clone MGC:1080, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20011 /DB_XREF=gi:13111838 /UG=Hs.256583 interleukin enhancer binding factor 3, 90kD /FL=gb:BC003086.1 gb:NM_004516.1 gb:U10324.1 gb:AF167570.1 gb:NM_012218.1 BC003086 interleukin enhancer binding factor 3, 90kDa ILF3 3609 NM_001137673 /// NM_004516 /// NM_012218 /// NM_017620 /// NM_153464 /// XM_005259895 /// XM_006722742 0000279 // M phase // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217805_at NM_004516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004516.1 /DEF=Homo sapiens interleukin enhancer binding factor 3, 90kD (ILF3), mRNA. /FEA=mRNA /GEN=ILF3 /PROD=interleukin enhancer binding factor 3, 90kD /DB_XREF=gi:4758603 /UG=Hs.256583 interleukin enhancer binding factor 3, 90kD /FL=gb:BC003086.1 gb:NM_004516.1 gb:U10324.1 gb:AF167570.1 gb:NM_012218.1 NM_004516 interleukin enhancer binding factor 3, 90kDa ILF3 3609 NM_001137673 /// NM_004516 /// NM_012218 /// NM_017620 /// NM_153464 /// XM_005259895 /// XM_006722742 0000279 // M phase // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0045071 // negative regulation of viral genome replication // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217806_s_at NM_015584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015584.1 /DEF=Homo sapiens DKFZP586F1524 protein (DKFZP586F1524), mRNA. /FEA=mRNA /GEN=DKFZP586F1524 /PROD=DKFZP586F1524 protein /DB_XREF=gi:7661671 /UG=Hs.241543 DKFZP586F1524 protein /FL=gb:BC000655.1 gb:AF077203.1 gb:NM_015584.1 NM_015584 polymerase (DNA-directed), delta interacting protein 2 POLDIP2 26073 NM_001290145 /// NM_015584 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 217807_s_at NM_015710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015710.1 /DEF=Homo sapiens glioma tumor suppressor candidate region gene 2 (GLTSCR2), mRNA. /FEA=mRNA /GEN=GLTSCR2 /PROD=glioma tumor suppressor candidate region gene 2 /DB_XREF=gi:7657129 /UG=Hs.2237 glioma tumor suppressor candidate region gene 2 /FL=gb:AF182076.1 gb:NM_015710.1 NM_015710 glioma tumor suppressor candidate region gene 2 /// small nucleolar RNA, C/D box 23 GLTSCR2 /// SNORD23 29997 /// 692091 NM_015710 /// NR_003048 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 217808_s_at NM_024117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024117.1 /DEF=Homo sapiens hypothetical protein MGC2745 (MGC2745), mRNA. /FEA=mRNA /GEN=MGC2745 /PROD=hypothetical protein MGC2745 /DB_XREF=gi:13129137 /UG=Hs.324178 hypothetical protein MGC2745 /FL=gb:BC002326.1 gb:BC003044.1 gb:NM_024117.1 NM_024117 mitogen-activated protein kinase associated protein 1 MAPKAP1 79109 NM_001006617 /// NM_001006618 /// NM_001006619 /// NM_001006620 /// NM_001006621 /// NM_024117 0006950 // response to stress // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0031295 // T cell costimulation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046580 // negative regulation of Ras protein signal transduction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0070300 // phosphatidic acid binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 217809_at NM_014038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014038.1 /DEF=Homo sapiens HSPC028 protein (HSPC028), mRNA. /FEA=mRNA /GEN=HSPC028 /PROD=HSPC028 protein /DB_XREF=gi:7661743 /UG=Hs.5216 HSPC028 protein /FL=gb:AF110323.1 gb:BC003056.1 gb:AF083246.1 gb:NM_014038.1 NM_014038 basic leucine zipper and W2 domains 2 BZW2 28969 NM_001159767 /// NM_014038 /// NR_027624 /// XM_006715706 /// XM_006715707 /// XM_006715708 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 217810_x_at NM_020117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020117.1 /DEF=Homo sapiens hypothetical protein FLJ10595 (FLJ10595), mRNA. /FEA=mRNA /GEN=FLJ10595 /PROD=hypothetical protein FLJ10595 /DB_XREF=gi:9910223 /UG=Hs.6762 hypothetical protein FLJ10595 /FL=gb:D84223.1 gb:NM_020117.1 NM_020117 leucyl-tRNA synthetase LARS 51520 NM_020117 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006429 // leucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004823 // leucine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 217811_at NM_016275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016275.1 /DEF=Homo sapiens selenoprotein T (LOC51714), mRNA. /FEA=mRNA /GEN=LOC51714 /PROD=selenoprotein T /DB_XREF=gi:7706470 /UG=Hs.8148 selenoprotein T /FL=gb:AF131856.1 gb:AF195141.1 gb:NM_016275.1 NM_016275 selenoprotein T SELT 51714 NM_016275 0001514 // selenocysteine incorporation // non-traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0008430 // selenium binding // non-traceable author statement 217812_at NM_016258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016258.1 /DEF=Homo sapiens high-glucose-regulated protein 8 (HGRG8), mRNA. /FEA=mRNA /GEN=HGRG8 /PROD=high-glucose-regulated protein 8 /DB_XREF=gi:7705410 /UG=Hs.20993 high-glucose-regulated protein 8 /FL=gb:BC002559.1 gb:AF155095.1 gb:AF192968.1 gb:NM_016258.1 NM_016258 YTH domain family, member 2 YTHDF2 51441 NM_001172828 /// NM_001173128 /// NM_016258 0006959 // humoral immune response // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 1990247 // N6-methyladenosine-containing RNA binding // inferred from direct assay 217813_s_at NM_006717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006717.1 /DEF=Homo sapiens spindlin (SPIN), mRNA. /FEA=mRNA /GEN=SPIN /PROD=spindlin /DB_XREF=gi:5730064 /UG=Hs.289043 spindlin /FL=gb:AL136719.1 gb:AF087864.1 gb:AF317228.2 gb:AF106682.1 gb:NM_006717.1 NM_006717 spindlin 1 SPIN1 10927 NM_006717 0007049 // cell cycle // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007276 // gamete generation // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 217814_at NM_020198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020198.1 /DEF=Homo sapiens GK001 protein (GK001), mRNA. /FEA=mRNA /GEN=GK001 /PROD=GK001 protein /DB_XREF=gi:9910241 /UG=Hs.8207 GK001 protein /FL=gb:AF113221.1 gb:BC001300.1 gb:AF226054.1 gb:NM_020198.1 NM_020198 coiled-coil domain containing 47 CCDC47 57003 NM_020198 /// XM_005257527 0001649 // osteoblast differentiation // inferred from direct assay /// 0006983 // ER overload response // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217815_at NM_007192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007192.1 /DEF=Homo sapiens chromatin-specific transcription elongation factor, 140 kDa subunit (FACTP140), mRNA. /FEA=mRNA /GEN=FACTP140 /PROD=chromatin-specific transcription elongationfactor, 140 kDa subunit /DB_XREF=gi:6005756 /UG=Hs.14963 chromatin-specific transcription elongation factor, 140 kDa subunit /FL=gb:AF152961.1 gb:NM_007192.1 NM_007192 suppressor of Ty 16 homolog (S. cerevisiae) SUPT16H 11198 NM_007192 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217816_s_at NM_020357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020357.1 /DEF=Homo sapiens PEST-containing nuclear protein (pcnp), mRNA. /FEA=mRNA /GEN=pcnp /PROD=PEST-containing nuclear protein /DB_XREF=gi:9966826 /UG=Hs.283728 PEST-containing nuclear protein /FL=gb:AB037675.1 gb:NM_020357.1 NM_020357 PEST proteolytic signal containing nuclear protein PCNP 57092 NM_020357 0007049 // cell cycle // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217817_at BE891920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE891920 /FEA=EST /DB_XREF=gi:10351728 /DB_XREF=est:601435490F1 /CLONE=IMAGE:3920590 /UG=Hs.323342 actin related protein 23 complex, subunit 4 (20 kD) /FL=gb:AF006087.1 gb:NM_005718.1 BE891920 actin related protein 2/3 complex, subunit 4, 20kDa ARPC4 10093 NM_001024959 /// NM_001024960 /// NM_001198780 /// NM_005718 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement 217818_s_at NM_005718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005718.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 4 (20 kD) (ARPC4), mRNA. /FEA=mRNA /GEN=ARPC4 /PROD=actin related protein 23 complex, subunit 4 (20kD) /DB_XREF=gi:5031594 /UG=Hs.323342 actin related protein 23 complex, subunit 4 (20 kD) /FL=gb:AF006087.1 gb:NM_005718.1 NM_005718 actin related protein 2/3 complex, subunit 4, 20kDa ARPC4 10093 NM_001024959 /// NM_001024960 /// NM_001198780 /// NM_005718 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement 217819_at NM_016099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016099.1 /DEF=Homo sapiens HSPC041 protein (LOC51125), mRNA. /FEA=mRNA /GEN=LOC51125 /PROD=HSPC041 protein /DB_XREF=gi:7705820 /UG=Hs.7953 HSPC041 protein /FL=gb:AF125102.1 gb:NM_016099.1 NM_016099 golgin A7 GOLGA7 51125 NM_001002296 /// NM_001174124 /// NM_016099 0018230 // peptidyl-L-cysteine S-palmitoylation // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0002178 // palmitoyltransferase complex // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217820_s_at NM_018212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018212.1 /DEF=Homo sapiens hypothetical protein FLJ10773 (FLJ10773), mRNA. /FEA=mRNA /GEN=FLJ10773 /PROD=hypothetical protein FLJ10773 /DB_XREF=gi:8922657 /UG=Hs.14838 hypothetical protein FLJ10773 /FL=gb:NM_018212.1 NM_018212 enabled homolog (Drosophila) ENAH 55740 NM_001008493 /// NM_018212 /// XM_005273182 /// XM_005273187 /// XM_005273188 /// XM_005273189 /// XM_006711786 /// XM_006711787 /// XM_006711788 /// XM_006711789 /// XM_006711790 /// XM_006711791 /// XM_006711792 /// XM_006711793 /// XM_006711794 /// XM_006711795 /// XM_006711796 /// XM_006711797 0001843 // neural tube closure // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 217821_s_at AF118023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118023.1 /DEF=Homo sapiens SH3 domain-binding protein SNP70 mRNA, complete cds. /FEA=mRNA /PROD=SH3 domain-binding protein SNP70 /DB_XREF=gi:4836400 /UG=Hs.16420 Npw38-binding protein NpwBP /FL=gb:BC001621.1 gb:AF118023.1 gb:AB029309.1 gb:NM_016312.1 AF118023 WW domain binding protein 11 WBP11 51729 NM_016312 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008599 // protein phosphatase type 1 regulator activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 217822_at NM_016312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016312.1 /DEF=Homo sapiens Npw38-binding protein NpwBP (LOC51729), mRNA. /FEA=mRNA /GEN=LOC51729 /PROD=Npw38-binding protein NpwBP /DB_XREF=gi:7706500 /UG=Hs.16420 Npw38-binding protein NpwBP /FL=gb:BC001621.1 gb:AF118023.1 gb:AB029309.1 gb:NM_016312.1 NM_016312 WW domain binding protein 11 WBP11 51729 NM_016312 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008599 // protein phosphatase type 1 regulator activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 217823_s_at AL562528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL562528 /FEA=EST /DB_XREF=gi:12911037 /DB_XREF=est:AL562528 /CLONE=CS0DC012YI08 (3 prime) /UG=Hs.184325 CGI-76 protein /FL=gb:AF151834.1 gb:AF161502.1 gb:AF151039.1 gb:NM_016021.1 AL562528 ubiquitin-conjugating enzyme E2, J1 UBE2J1 51465 NM_016021 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217824_at AW500009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW500009 /FEA=EST /DB_XREF=gi:7112213 /DB_XREF=est:UI-HF-BN0-aki-e-09-0-UI.r1 /CLONE=IMAGE:3077105 /UG=Hs.184325 CGI-76 protein /FL=gb:AF151834.1 gb:AF161502.1 gb:AF151039.1 gb:NM_016021.1 AW500009 ubiquitin-conjugating enzyme E2, J1 UBE2J1 51465 NM_016021 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217825_s_at AF151039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151039.1 /DEF=Homo sapiens HSPC205 mRNA, complete cds. /FEA=mRNA /PROD=HSPC205 /DB_XREF=gi:7106799 /UG=Hs.184325 CGI-76 protein /FL=gb:AF151834.1 gb:AF161502.1 gb:AF151039.1 gb:NM_016021.1 AF151039 ubiquitin-conjugating enzyme E2, J1 UBE2J1 51465 NM_016021 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217826_s_at NM_016021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016021.1 /DEF=Homo sapiens CGI-76 protein (LOC51632), mRNA. /FEA=mRNA /GEN=LOC51632 /PROD=CGI-76 protein /DB_XREF=gi:7706311 /UG=Hs.184325 CGI-76 protein /FL=gb:AF151834.1 gb:AF161502.1 gb:AF151039.1 gb:NM_016021.1 NM_016021 ubiquitin-conjugating enzyme E2, J1 UBE2J1 51465 NM_016021 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217827_s_at NM_016630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016630.2 /DEF=Homo sapiens acid cluster protein 33 (ACP33), mRNA. /FEA=mRNA /GEN=ACP33 /PROD=acid cluster protein 33 /DB_XREF=gi:13699804 /UG=Hs.71475 acid cluster protein 33 /FL=gb:BC000244.1 gb:NM_016630.2 gb:AF208861.1 NM_016630 spastic paraplegia 21 (autosomal recessive, Mast syndrome) SPG21 51324 NM_001127889 /// NM_001127890 /// NM_016630 /// XM_005254436 /// XM_005254437 /// XM_006720564 0008219 // cell death // inferred from electronic annotation /// 0050851 // antigen receptor-mediated signaling pathway // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay 0042609 // CD4 receptor binding // inferred from physical interaction 217828_at NM_024755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024755.1 /DEF=Homo sapiens hypothetical protein FLJ13213 (FLJ13213), mRNA. /FEA=mRNA /GEN=FLJ13213 /PROD=hypothetical protein FLJ13213 /DB_XREF=gi:13376087 /UG=Hs.126925 hypothetical protein FLJ13213 /FL=gb:NM_024755.1 NM_024755 SAFB-like, transcription modulator SLTM 79811 NM_001013843 /// NM_017968 /// NM_024755 /// XM_005254669 /// XM_006720685 /// XM_006720686 /// XM_006720687 /// XM_006720688 /// XM_006720689 /// XM_006720690 /// XR_243128 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217829_s_at NM_006590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006590.1 /DEF=Homo sapiens SnRNP assembly defective 1 homolog (SAD1), mRNA. /FEA=mRNA /GEN=SAD1 /PROD=SnRNP assembly defective 1 homolog /DB_XREF=gi:5730024 /UG=Hs.12820 SnRNP assembly defective 1 homolog /FL=gb:AF130096.1 gb:BC001384.1 gb:AF132955.1 gb:NM_006590.1 NM_006590 ubiquitin specific peptidase 39 USP39 10713 NM_001256725 /// NM_001256726 /// NM_001256727 /// NM_001256728 /// NM_006590 /// NR_046347 /// XM_006711922 /// XM_006711923 0000245 // spliceosomal complex assembly // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217830_s_at AL109658 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109658 /DEF=Human DNA sequence from clone RP4-776F14 on chromosome 20p12.2-13. Contains the 5 end of the FKBP1A gene for FK506-binding protein 1A (12kD), the gene for P47 protein, part of a novel member of the PTPNS (protein tyrosine phosphatase, non-recepto... /FEA=mRNA /DB_XREF=gi:7161806 /UG=Hs.12865 p47 /FL=gb:BC002801.1 gb:AF078856.1 gb:NM_016143.1 AL109658 NSFL1 (p97) cofactor (p47) NSFL1C 55968 NM_001206736 /// NM_016143 /// NM_018839 /// NM_182483 /// NR_038164 /// XM_006723591 /// XM_006723592 /// XM_006723593 /// XM_006723594 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 217831_s_at NM_016143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016143.1 /DEF=Homo sapiens p47 (LOC51674), mRNA. /FEA=mRNA /GEN=LOC51674 /PROD=p47 /DB_XREF=gi:7706394 /UG=Hs.12865 p47 /FL=gb:BC002801.1 gb:AF078856.1 gb:NM_016143.1 NM_016143 NSFL1 (p97) cofactor (p47) NSFL1C 55968 NM_001206736 /// NM_016143 /// NM_018839 /// NM_182483 /// NR_038164 /// XM_006723591 /// XM_006723592 /// XM_006723593 /// XM_006723594 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 217832_at BE672181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE672181 /FEA=EST /DB_XREF=gi:10032712 /DB_XREF=est:7b51c08.x1 /CLONE=IMAGE:3231758 /UG=Hs.155489 NS1-associated protein 1 /FL=gb:AF155568.1 gb:NM_006372.1 BE672181 synaptotagmin binding, cytoplasmic RNA interacting protein SYNCRIP 10492 NM_001159673 /// NM_001159674 /// NM_001159675 /// NM_001159676 /// NM_001159677 /// NM_001253771 /// NM_006372 /// XM_005248635 /// XM_005248636 /// XM_005248637 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217833_at AL520908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL520908 /FEA=EST /DB_XREF=gi:12784401 /DB_XREF=est:AL520908 /CLONE=CS0DB002YF01 (3 prime) /UG=Hs.155489 NS1-associated protein 1 /FL=gb:AF155568.1 gb:NM_006372.1 AL520908 synaptotagmin binding, cytoplasmic RNA interacting protein SYNCRIP 10492 NM_001159673 /// NM_001159674 /// NM_001159675 /// NM_001159676 /// NM_001159677 /// NM_001253771 /// NM_006372 /// XM_005248635 /// XM_005248636 /// XM_005248637 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217834_s_at NM_006372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006372.1 /DEF=Homo sapiens NS1-associated protein 1 (NSAP1), mRNA. /FEA=mRNA /GEN=NSAP1 /PROD=NS1-associated protein 1 /DB_XREF=gi:5453805 /UG=Hs.155489 NS1-associated protein 1 /FL=gb:AF155568.1 gb:NM_006372.1 NM_006372 synaptotagmin binding, cytoplasmic RNA interacting protein SYNCRIP 10492 NM_001159673 /// NM_001159674 /// NM_001159675 /// NM_001159676 /// NM_001159677 /// NM_001253771 /// NM_006372 /// XM_005248635 /// XM_005248636 /// XM_005248637 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071204 // histone pre-mRNA 3'end processing complex // inferred from sequence or structural similarity /// 0097452 // GAIT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217835_x_at NM_018840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018840.1 /DEF=Homo sapiens putative Rab5-interacting protein (LOC55969), mRNA. /FEA=mRNA /GEN=LOC55969 /PROD=putative Rab5-interacting protein /DB_XREF=gi:10047115 /UG=Hs.184062 putative Rab5-interacting protein /FL=gb:NM_018840.1 gb:AF274936.1 gb:AF112213.1 NM_018840 chromosome 20 open reading frame 24 /// TGIF2-C20orf24 readthrough C20orf24 /// TGIF2-C20orf24 55969 /// 100527943 NM_001199534 /// NM_001199535 /// NM_018840 /// NM_199483 /// NM_199484 /// NM_199485 /// NR_026562 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217836_s_at NM_018253 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018253.1 /DEF=Homo sapiens hypothetical protein FLJ10875 (FLJ10875), mRNA. /FEA=mRNA /GEN=FLJ10875 /PROD=hypothetical protein FLJ10875 /DB_XREF=gi:8922730 /UG=Hs.18851 hypothetical protein FLJ10875 /FL=gb:BC001655.1 gb:BC001843.1 gb:NM_018253.1 NM_018253 YY1 associated protein 1 YY1AP1 55249 NM_001198899 /// NM_001198900 /// NM_001198901 /// NM_001198902 /// NM_001198903 /// NM_001198904 /// NM_001198905 /// NM_001198906 /// NM_018253 /// NM_139118 /// NM_139119 /// NM_139120 /// NM_139121 /// XM_006711432 /// XM_006711433 /// XM_006711434 /// XM_006711435 /// XM_006711436 /// XR_426788 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217837_s_at NM_016079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016079.1 /DEF=Homo sapiens CGI-149 protein (LOC51652), mRNA. /FEA=mRNA /GEN=LOC51652 /PROD=CGI-149 protein /DB_XREF=gi:7706352 /UG=Hs.189658 CGI-149 protein /FL=gb:BC004419.1 gb:AF151907.1 gb:AF219226.1 gb:NM_016079.1 NM_016079 charged multivesicular body protein 3 /// RNF103-CHMP3 readthrough CHMP3 /// RNF103-CHMP3 51652 /// 100526767 NM_001005753 /// NM_001193517 /// NM_001198954 /// NM_016079 /// NR_036454 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0050792 // regulation of viral process // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1902188 // positive regulation of viral release from host cell // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217838_s_at NM_016337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016337.1 /DEF=Homo sapiens RNB6 (RNB6), mRNA. /FEA=mRNA /GEN=RNB6 /PROD=RNB6 /DB_XREF=gi:7706686 /UG=Hs.241471 RNB6 /FL=gb:AF052504.1 gb:NM_016337.1 NM_016337 Enah/Vasp-like EVL 51466 NM_016337 /// XM_005267749 /// XM_006720168 /// XM_006720169 /// XM_006720170 0007015 // actin filament organization // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 1900028 // negative regulation of ruffle assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from sequence or structural similarity /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity 217839_at NM_006070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006070.1 /DEF=Homo sapiens TRK-fused gene (TFG), mRNA. /FEA=mRNA /GEN=TFG /PROD=TRK-fused gene /DB_XREF=gi:5174718 /UG=Hs.250897 TRK-fused gene /FL=gb:NM_006070.1 NM_006070 TRK-fused gene TFG 10342 NM_001007565 /// NM_001195478 /// NM_001195479 /// NM_006070 /// XM_005247066 /// XM_006713472 /// XM_006713473 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005737 // cytoplasm // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 217840_at NM_016222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016222.1 /DEF=Homo sapiens DEAD-box protein abstrakt (ABS), mRNA. /FEA=mRNA /GEN=ABS /PROD=DEAD-box protein abstrakt /DB_XREF=gi:7705259 /UG=Hs.274317 DEAD-box protein abstrakt /FL=gb:AF195417.1 gb:NM_016222.1 NM_016222 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 DDX41 51428 NM_016222 /// XM_006714870 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217841_s_at NM_016147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016147.1 /DEF=Homo sapiens protein phosphatase methylesterase-1 (PME-1), mRNA. /FEA=mRNA /GEN=PME-1 /PROD=protein phosphatase methylesterase-1 /DB_XREF=gi:7706644 /UG=Hs.63304 protein phosphatase methylesterase-1 /FL=gb:BC003046.1 gb:AF157028.1 gb:NM_016147.1 NM_016147 protein phosphatase methylesterase 1 PPME1 51400 NM_001271593 /// NM_016147 /// XR_428916 0006482 // protein demethylation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0051722 // protein C-terminal methylesterase activity // inferred from direct assay /// 0052689 // carboxylic ester hydrolase activity // inferred from electronic annotation 217842_at NM_016019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016019.1 /DEF=Homo sapiens CGI-74 protein (LOC51631), mRNA. /FEA=mRNA /GEN=LOC51631 /PROD=CGI-74 protein /DB_XREF=gi:7706309 /UG=Hs.7194 CGI-74 protein /FL=gb:AF151832.1 gb:NM_016019.1 NM_016019 C7orf55-LUC7L2 readthrough /// LUC7-like 2 (S. cerevisiae) C7orf55-LUC7L2 /// LUC7L2 51631 /// 100996928 NM_001244584 /// NM_001244585 /// NM_001270643 /// NM_016019 0006376 // mRNA splice site selection // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217843_s_at NM_014166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014166.1 /DEF=Homo sapiens HSPC126 protein (HSPC126), mRNA. /FEA=mRNA /GEN=HSPC126 /PROD=HSPC126 protein /DB_XREF=gi:7661787 /UG=Hs.181112 HSPC126 protein /FL=gb:AF300618.1 gb:BC005189.1 gb:AF161475.1 gb:AF230381.1 gb:NM_014166.1 NM_014166 mediator complex subunit 4 MED4 29079 NM_001270629 /// NM_014166 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 217844_at NM_021198 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021198.1 /DEF=Homo sapiens nuclear LIM interactor-interacting factor (NLI-IF), mRNA. /FEA=mRNA /GEN=NLI-IF /PROD=nuclear LIM interactor-interacting factor /DB_XREF=gi:10864008 /UG=Hs.283724 nuclear LIM interactor-interacting factor /FL=gb:AF229162.1 gb:NM_021198.1 NM_021198 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 CTDSP1 58190 NM_001206878 /// NM_001206879 /// NM_021198 /// NM_182642 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008420 // CTD phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217845_x_at NM_014056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014056.1 /DEF=Homo sapiens DKFZP564K247 protein (DKFZP564K247), mRNA. /FEA=mRNA /GEN=DKFZP564K247 /PROD=DKFZP564K247 protein /DB_XREF=gi:7661619 /UG=Hs.7917 DKFZP564K247 protein /FL=gb:BC000601.1 gb:AF077034.1 gb:AF145385.1 gb:AL110233.1 gb:NM_014056.1 NM_014056 HIG1 hypoxia inducible domain family, member 1A HIGD1A 25994 NM_001099668 /// NM_001099669 /// NM_014056 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 217846_at NM_005051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005051.1 /DEF=Homo sapiens glutaminyl-tRNA synthetase (QARS), mRNA. /FEA=mRNA /GEN=QARS /PROD=glutaminyl-tRNA synthetase /DB_XREF=gi:4826959 /UG=Hs.79322 glutaminyl-tRNA synthetase /FL=gb:AF130067.1 gb:BC000394.1 gb:BC001772.1 gb:NM_005051.1 NM_005051 microRNA 6890 /// glutaminyl-tRNA synthetase MIR6890 /// QARS 5859 /// 102465536 NM_001272073 /// NM_005051 /// NR_073590 /// NR_106950 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006425 // glutaminyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004819 // glutamine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation 217847_s_at NM_005119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005119.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein, 150 kDa subunit (TRAP150), mRNA. /FEA=mRNA /GEN=TRAP150 /PROD=thyroid hormone receptor-associated protein, 150kDa subunit /DB_XREF=gi:4827039 /UG=Hs.108319 thyroid hormone receptor-associated protein, 150 kDa subunit /FL=gb:AF117756.1 gb:NM_005119.1 NM_005119 thyroid hormone receptor associated protein 3 THRAP3 9967 NM_005119 /// XM_005271371 /// XR_246308 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048255 // mRNA stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from direct assay 217848_s_at NM_021129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021129.1 /DEF=Homo sapiens pyrophosphatase (inorganic) (PP), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PP /PROD=pyrophosphatase (inorganic) /DB_XREF=gi:11056043 /UG=Hs.184011 pyrophosphatase (inorganic) /FL=gb:NM_021129.1 gb:AF217186.1 gb:BC001022.1 gb:AF154065.1 gb:AB026723.1 gb:AF119665.1 NM_021129 pyrophosphatase (inorganic) 1 PPA1 5464 NM_021129 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0071344 // diphosphate metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004427 // inorganic diphosphatase activity // not recorded /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217849_s_at NM_006035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006035.1 /DEF=Homo sapiens CDC42-binding protein kinase beta (DMPK-like) (CDC42BPB), mRNA. /FEA=mRNA /GEN=CDC42BPB /PROD=CDC42-binding protein kinase beta (DMPK-like) /DB_XREF=gi:5174412 /UG=Hs.12908 CDC42-binding protein kinase beta (DMPK-like) /FL=gb:AF128625.1 gb:NM_006035.1 NM_006035 CDC42 binding protein kinase beta (DMPK-like) CDC42BPB 9578 NM_006035 /// XM_005268227 /// XM_005268228 /// XM_005268229 /// XM_005268230 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217850_at NM_014366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014366.1 /DEF=Homo sapiens putative nucleotide binding protein, estradiol-induced (E2IG3), mRNA. /FEA=mRNA /GEN=E2IG3 /PROD=putative nucleotide binding protein,estradiol-induced /DB_XREF=gi:7657047 /UG=Hs.279923 putative nucleotide binding protein, estradiol-induced /FL=gb:BC001024.1 gb:AF191018.1 gb:NM_014366.1 NM_014366 guanine nucleotide binding protein-like 3 (nucleolar) /// small nucleolar RNA, C/D box 19B GNL3 /// SNORD19B 26354 /// 100113381 NM_014366 /// NM_206825 /// NM_206826 /// NR_003687 0006184 // GTP catabolic process // not recorded /// 0008283 // cell proliferation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042254 // ribosome biogenesis // not recorded 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // not recorded /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 217851_s_at NM_016045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016045.1 /DEF=Homo sapiens CGI-107 protein (LOC51012), mRNA. /FEA=mRNA /GEN=LOC51012 /PROD=CGI-107 protein /DB_XREF=gi:7705609 /UG=Hs.3945 CGI-107 protein /FL=gb:AF151865.1 gb:NM_016045.1 NM_016045 slowmo homolog 2 (Drosophila) SLMO2 51012 NM_001256403 /// NM_016045 0015914 // phospholipid transport // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // not recorded 1990050 // phosphatidic acid transporter activity // not recorded 217852_s_at NM_018184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018184.1 /DEF=Homo sapiens hypothetical protein FLJ10702 (FLJ10702), mRNA. /FEA=mRNA /GEN=FLJ10702 /PROD=hypothetical protein FLJ10702 /DB_XREF=gi:8922600 /UG=Hs.104222 hypothetical protein FLJ10702 /FL=gb:NM_018184.1 NM_018184 ADP-ribosylation factor-like 8B ARL8B 55207 NM_018184 /// XM_005265295 0006184 // GTP catabolic process // non-traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay 217853_at NM_022748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022748.1 /DEF=Homo sapiens hypothetical protein FLJ13732 similar to tensin (FLJ13732), mRNA. /FEA=mRNA /GEN=FLJ13732 /PROD=hypothetical protein FLJ13732 similar to tensin /DB_XREF=gi:12232408 /UG=Hs.12210 hypothetical protein FLJ13732 similar to tensin /FL=gb:NM_022748.1 NM_022748 tensin 3 TNS3 64759 NM_022748 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217854_s_at NM_002695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002695.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide E (25kD) (POLR2E), mRNA. /FEA=mRNA /GEN=POLR2E /PROD=polymerase (RNA) II (DNA directed) polypeptide E(25kD) /DB_XREF=gi:4505944 /UG=Hs.24301 polymerase (RNA) II (DNA directed) polypeptide E (25kD) /FL=gb:BC004441.1 gb:NM_002695.1 gb:J04965.1 gb:D38251.1 NM_002695 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa POLR2E 5434 NM_002695 /// XM_005259579 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217855_x_at NM_016547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016547.1 /DEF=Homo sapiens calcium binding protein Cab45 precursor, (LOC51767), mRNA. /FEA=mRNA /GEN=LOC51767 /PROD=calcium binding protein Cab45 precursor, /DB_XREF=gi:7706572 /UG=Hs.42806 calcium binding protein Cab45 precursor, /FL=gb:AF178986.1 gb:NM_016547.1 NM_016547 stromal cell derived factor 4 SDF4 51150 NM_016176 /// NM_016547 0006887 // exocytosis // inferred from electronic annotation /// 0009650 // UV protection // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0070625 // zymogen granule exocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 217856_at AF182415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF182415.1 /DEF=Homo sapiens MDS014 (MDS014) mRNA, complete cds. /FEA=mRNA /GEN=MDS014 /PROD=MDS014 /DB_XREF=gi:10197629 /UG=Hs.65648 RNA binding motif protein 8A /FL=gb:AF182415.1 gb:AF231511.1 gb:AF127761.1 gb:NM_005105.1 gb:AF161463.1 gb:AF198620.1 AF182415 RNA binding motif protein 8A RBM8A 9939 NM_005105 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217857_s_at NM_005105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005105.1 /DEF=Homo sapiens RNA binding motif protein 8A (RBM8A), mRNA. /FEA=mRNA /GEN=RBM8A /PROD=RNA binding motif protein 8A /DB_XREF=gi:4826971 /UG=Hs.65648 RNA binding motif protein 8A /FL=gb:AF182415.1 gb:AF231511.1 gb:AF127761.1 gb:NM_005105.1 gb:AF161463.1 gb:AF198620.1 NM_005105 RNA binding motif protein 8A RBM8A 9939 NM_005105 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217858_s_at NM_016607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016607.1 /DEF=Homo sapiens ALEX3 protein (ALEX3), mRNA. /FEA=mRNA /GEN=ALEX3 /PROD=ALEX3 protein /DB_XREF=gi:7705273 /UG=Hs.172788 ALEX3 protein /FL=gb:AB039669.1 gb:NM_016607.1 NM_016607 armadillo repeat containing, X-linked 3 ARMCX3 51566 NM_016607 /// NM_177947 /// NM_177948 /// XM_005262141 0034613 // cellular protein localization // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 217859_s_at NM_018375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018375.1 /DEF=Homo sapiens hypothetical protein FLJ11274 (FLJ11274), mRNA. /FEA=mRNA /GEN=FLJ11274 /PROD=hypothetical protein FLJ11274 /DB_XREF=gi:8922967 /UG=Hs.18104 hypothetical protein FLJ11274 /FL=gb:NM_018375.1 NM_018375 solute carrier family 39, member 9 SLC39A9 55334 NM_001252148 /// NM_001252150 /// NM_001252151 /// NM_001252152 /// NM_018375 /// XM_005267834 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 217860_at NM_004544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004544.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD) (NDUFA10), mRNA. /FEA=mRNA /GEN=NDUFA10 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 10 (42kD) /DB_XREF=gi:4758767 /UG=Hs.198271 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD) /FL=gb:BC003417.1 gb:AF087661.1 gb:NM_004544.1 NM_004544 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa NDUFA10 4705 NM_004544 /// XM_005247006 /// XM_006712543 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 217861_s_at NM_013388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013388.1 /DEF=Homo sapiens prolactin regulatory element binding (PREB), mRNA. /FEA=mRNA /GEN=PREB /PROD=prolactin regulatory element binding /DB_XREF=gi:7019502 /UG=Hs.279784 prolactin regulatory element binding /FL=gb:BC002765.1 gb:AF203687.1 gb:NM_013388.1 gb:AF226684.1 NM_013388 prolactin regulatory element binding PREB 10113 NM_013388 /// XM_006711914 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 217862_at N24868 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N24868 /FEA=EST /DB_XREF=gi:1139018 /DB_XREF=est:yx70h06.s1 /CLONE=IMAGE:267131 /UG=Hs.75251 DEADH (Asp-Glu-Ala-AspHis) box binding protein 1 /FL=gb:AF077951.1 gb:AF167160.1 gb:NM_016166.1 N24868 protein inhibitor of activated STAT, 1 PIAS1 8554 NM_016166 /// XM_005254734 /// XM_005254735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 217863_at AI348378 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348378 /FEA=EST /DB_XREF=gi:4085584 /DB_XREF=est:qo20h06.x1 /CLONE=IMAGE:1909115 /UG=Hs.75251 DEADH (Asp-Glu-Ala-AspHis) box binding protein 1 /FL=gb:AF077951.1 gb:AF167160.1 gb:NM_016166.1 AI348378 protein inhibitor of activated STAT, 1 PIAS1 8554 NM_016166 /// XM_005254734 /// XM_005254735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 217864_s_at NM_016166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016166.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box binding protein 1 (DDXBP1), mRNA. /FEA=mRNA /GEN=DDXBP1 /PROD=DEADH (Asp-Glu-Ala-AspHis) box binding protein1 /DB_XREF=gi:7706636 /UG=Hs.75251 DEADH (Asp-Glu-Ala-AspHis) box binding protein 1 /FL=gb:AF077951.1 gb:AF167160.1 gb:NM_016166.1 NM_016166 protein inhibitor of activated STAT, 1 PIAS1 8554 NM_016166 /// XM_005254734 /// XM_005254735 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 217865_at NM_018434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018434.1 /DEF=Homo sapiens goliath protein (LOC55819), mRNA. /FEA=mRNA /GEN=LOC55819 /PROD=goliath protein /DB_XREF=gi:10092650 /UG=Hs.102737 goliath protein /FL=gb:NM_018434.1 NM_018434 ring finger protein 130 RNF130 55819 NM_001280801 /// NM_018434 /// XM_006714890 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217866_at NM_024811 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024811.1 /DEF=Homo sapiens hypothetical protein FLJ12529 (FLJ12529), mRNA. /FEA=mRNA /GEN=FLJ12529 /PROD=hypothetical protein FLJ12529 /DB_XREF=gi:13376196 /UG=Hs.169100 hypothetical protein FLJ12529 /FL=gb:NM_024811.1 NM_024811 cleavage and polyadenylation specific factor 7, 59kDa CPSF7 79869 NM_001136040 /// NM_001142565 /// NM_024811 /// XM_005274298 /// XM_005274299 /// XM_005274302 /// XM_005274303 /// XM_006718690 /// XM_006718691 /// XM_006718692 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217867_x_at NM_012105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012105.1 /DEF=Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), mRNA. /FEA=mRNA /GEN=BACE2 /PROD=beta-site APP-cleaving enzyme 2 /DB_XREF=gi:6912263 /UG=Hs.271411 beta-site APP-cleaving enzyme 2 /FL=gb:AF117892.1 gb:AF050171.1 gb:AF200192.1 gb:AF200342.1 gb:AF204944.1 gb:AF178532.1 gb:NM_012105.1 NM_012105 beta-site APP-cleaving enzyme 2 BACE2 25825 NM_012105 /// NM_138991 /// NM_138992 0006508 // proteolysis // non-traceable author statement /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0016486 // peptide hormone processing // non-traceable author statement /// 0042985 // negative regulation of amyloid precursor protein biosynthetic process // inferred from mutant phenotype 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004190 // aspartic-type endopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 217868_s_at NM_016025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016025.1 /DEF=Homo sapiens CGI-81 protein (DREV1), mRNA. /FEA=mRNA /GEN=DREV1 /PROD=CGI-81 protein /DB_XREF=gi:7705788 /UG=Hs.279583 CGI-81 protein /FL=gb:BC000195.1 gb:AF151839.1 gb:NM_016025.1 NM_016025 methyltransferase like 9 METTL9 51108 NM_001077180 /// NM_001288659 /// NM_001288660 /// NM_016025 /// XM_006721049 0008152 // metabolic process // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation 217869_at NM_016142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016142.1 /DEF=Homo sapiens steroid dehydrogenase homolog (LOC51144), mRNA. /FEA=mRNA /GEN=LOC51144 /PROD=steroid dehydrogenase homolog /DB_XREF=gi:7705854 /UG=Hs.279617 steroid dehydrogenase homolog /FL=gb:AF078850.1 gb:NM_016142.1 NM_016142 hydroxysteroid (17-beta) dehydrogenase 12 HSD17B12 51144 NM_016142 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0001968 // fibronectin binding // inferred from electronic annotation /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 217870_s_at NM_016308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016308.1 /DEF=Homo sapiens UMP-CMP kinase (LOC51727), mRNA. /FEA=mRNA /GEN=LOC51727 /PROD=UMP-CMP kinase /DB_XREF=gi:7706496 /UG=Hs.11463 UMP-CMP kinase /FL=gb:AF259961.1 gb:AF110643.1 gb:AF112216.1 gb:AF070416.1 gb:NM_016308.1 NM_016308 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic CMPK1 51727 NM_001136140 /// NM_016308 /// NR_046394 /// NR_046395 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // traceable author statement /// 0006225 // UDP biosynthetic process // inferred from electronic annotation /// 0006227 // dUDP biosynthetic process // inferred from electronic annotation /// 0006240 // dCDP biosynthetic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0009220 // pyrimidine ribonucleotide biosynthetic process // traceable author statement /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046705 // CDP biosynthetic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0004127 // cytidylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004849 // uridine kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0009041 // uridylate kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0033862 // UMP kinase activity // inferred from electronic annotation 217871_s_at NM_002415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002415.1 /DEF=Homo sapiens macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIF), mRNA. /FEA=mRNA /GEN=MIF /PROD=macrophage migration inhibitory factor(glycosylation-inhibiting factor) /DB_XREF=gi:4505184 /UG=Hs.73798 macrophage migration inhibitory factor (glycosylation-inhibiting factor) /FL=gb:BC000447.1 gb:M25639.1 gb:L10612.1 gb:NM_002415.1 NM_002415 macrophage migration inhibitory factor (glycosylation-inhibiting factor) MIF 4282 NM_002415 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002906 // negative regulation of mature B cell apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007569 // cell aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010739 // positive regulation of protein kinase A signaling // inferred from direct assay /// 0019752 // carboxylic acid metabolic process // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from direct assay /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0043030 // regulation of macrophage activation // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0061078 // positive regulation of prostaglandin secretion involved in immune response // inferred from electronic annotation /// 0061081 // positive regulation of myeloid leukocyte cytokine production involved in immune response // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from physical interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 2000343 // positive regulation of chemokine (C-X-C motif) ligand 2 production // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004167 // dopachrome isomerase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005126 // cytokine receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0050178 // phenylpyruvate tautomerase activity // inferred from direct assay 217872_at NM_017916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017916.1 /DEF=Homo sapiens hypothetical protein FLJ20643 (FLJ20643), mRNA. /FEA=mRNA /GEN=FLJ20643 /PROD=hypothetical protein FLJ20643 /DB_XREF=gi:8923597 /UG=Hs.5245 hypothetical protein FLJ20643 /FL=gb:BC001108.1 gb:NM_017916.1 NM_017916 PIH1 domain containing 1 PIH1D1 55011 NM_017916 /// XM_006723254 /// XR_243941 /// XR_430202 /// XR_430203 0000492 // box C/D snoRNP assembly // inferred from mutant phenotype /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0070761 // pre-snoRNP complex // inferred from direct assay 217873_at NM_016289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016289.1 /DEF=Homo sapiens MO25 protein (LOC51719), mRNA. /FEA=mRNA /GEN=LOC51719 /PROD=MO25 protein /DB_XREF=gi:7706480 /UG=Hs.6406 MO25 protein /FL=gb:AF113536.1 gb:NM_016289.1 NM_016289 calcium binding protein 39 CAB39 51719 NM_001130849 /// NM_001130850 /// NM_016289 0007050 // cell cycle arrest // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071476 // cellular hypotonic response // inferred by curator /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred by curator /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred by curator /// 2000681 // negative regulation of rubidium ion transport // inferred by curator /// 2000687 // negative regulation of rubidium ion transmembrane transporter activity // inferred by curator 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay 217874_at NM_003849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003849.1 /DEF=Homo sapiens succinate-CoA ligase, GDP-forming, alpha subunit (SUCLG1), mRNA. /FEA=mRNA /GEN=SUCLG1 /PROD=succinate-CoA ligase, GDP-forming, alphasubunit /DB_XREF=gi:11321580 /UG=Hs.7043 succinate-CoA ligase, GDP-forming, alpha subunit /FL=gb:NM_003849.1 gb:BC000504.1 gb:AF104921.2 NM_003849 succinate-CoA ligase, alpha subunit SUCLG1 8802 NM_003849 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // inferred from electronic annotation /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045244 // succinate-CoA ligase complex (GDP-forming) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // inferred from electronic annotation /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0004776 // succinate-CoA ligase (GDP-forming) activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 217875_s_at NM_020182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020182.1 /DEF=Homo sapiens transmembrane, prostate androgen induced RNA (TMEPAI), mRNA. /FEA=mRNA /GEN=TMEPAI /PROD=transmembrane, prostate androgen induced RNA /DB_XREF=gi:9910497 /UG=Hs.83883 transmembrane, prostate androgen induced RNA /FL=gb:AF224278.1 gb:NM_020182.1 NM_020182 prostate transmembrane protein, androgen induced 1 PMEPA1 56937 NM_001255976 /// NM_020182 /// NM_199169 /// NM_199170 /// NM_199171 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030521 // androgen receptor signaling pathway // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031901 // early endosome membrane // traceable author statement 0050699 // WW domain binding // inferred from physical interaction 217876_at NM_012087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012087.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 5 (63kD) (GTF3C5), mRNA. /FEA=mRNA /GEN=GTF3C5 /PROD=general transcription factor IIIC, polypeptide 5(63kD) /DB_XREF=gi:6912401 /UG=Hs.286088 general transcription factor IIIC, polypeptide 5 (63kD) /FL=gb:AF133124.1 gb:NM_012087.1 NM_012087 general transcription factor IIIC, polypeptide 5, 63kDa GTF3C5 9328 NM_001122823 /// NM_001286709 /// NM_012087 /// XM_005272234 0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 217877_s_at NM_021639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021639.1 /DEF=Homo sapiens hypothetical protein SP192 (SP192), mRNA. /FEA=mRNA /GEN=SP192 /PROD=hypothetical protein SP192 /DB_XREF=gi:11056015 /UG=Hs.169854 hypothetical protein SP192 /FL=gb:NM_021639.1 NM_021639 GC-rich promoter binding protein 1-like 1 GPBP1L1 60313 NM_021639 /// XM_005271094 /// XM_005271095 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 217878_s_at AI203880 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI203880 /FEA=EST /DB_XREF=gi:3756486 /DB_XREF=est:qf77g07.x1 /CLONE=IMAGE:1756092 /UG=Hs.172405 cell division cycle 27 /FL=gb:NM_001256.1 AI203880 cell division cycle 27 CDC27 996 NM_001114091 /// NM_001256 /// NM_001293089 /// NM_001293091 /// XM_005257892 /// XM_005257895 /// XM_006722217 /// XM_006722218 /// XM_006722219 /// XM_006722220 /// XM_006722221 /// XR_429935 0000278 // mitotic cell cycle // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 217879_at AL566824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566824 /FEA=EST /DB_XREF=gi:12919571 /DB_XREF=est:AL566824 /CLONE=CS0DF025YN03 (3 prime) /UG=Hs.172405 cell division cycle 27 /FL=gb:NM_001256.1 AL566824 cell division cycle 27 CDC27 996 NM_001114091 /// NM_001256 /// NM_001293089 /// NM_001293091 /// XM_005257892 /// XM_005257895 /// XM_006722217 /// XM_006722218 /// XM_006722219 /// XM_006722220 /// XM_006722221 /// XR_429935 0000278 // mitotic cell cycle // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 217880_at N21397 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N21397 /FEA=EST /DB_XREF=gi:1126567 /DB_XREF=est:yx54e08.s1 /CLONE=IMAGE:265574 /UG=Hs.172405 cell division cycle 27 /FL=gb:NM_001256.1 N21397 cell division cycle 27 CDC27 996 NM_001114091 /// NM_001256 /// NM_001293089 /// NM_001293091 /// XM_005257892 /// XM_005257895 /// XM_006722217 /// XM_006722218 /// XM_006722219 /// XM_006722220 /// XM_006722221 /// XR_429935 0000278 // mitotic cell cycle // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 217881_s_at NM_001256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001256.1 /DEF=Homo sapiens cell division cycle 27 (CDC27), mRNA. /FEA=mRNA /GEN=CDC27 /PROD=cell division cycle 27 /DB_XREF=gi:4557015 /UG=Hs.172405 cell division cycle 27 /FL=gb:NM_001256.1 NM_001256 cell division cycle 27 CDC27 996 NM_001114091 /// NM_001256 /// NM_001293089 /// NM_001293091 /// XM_005257892 /// XM_005257895 /// XM_006722217 /// XM_006722218 /// XM_006722219 /// XM_006722220 /// XM_006722221 /// XR_429935 0000278 // mitotic cell cycle // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from mutant phenotype /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 217882_at NM_018447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018447.1 /DEF=Homo sapiens 30 kDa protein (LOC55831), mRNA. /FEA=mRNA /GEN=LOC55831 /PROD=30 kDa protein /DB_XREF=gi:8923856 /UG=Hs.283714 30 kDa protein /FL=gb:AF157321.1 gb:NM_018447.1 NM_018447 ER membrane protein complex subunit 3 EMC3 55831 NM_018447 /// XM_005265321 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 217883_at NM_015702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015702.1 /DEF=Homo sapiens hypothetical protein (CL25022), mRNA. /FEA=mRNA /GEN=CL25022 /PROD=hypothetical protein /DB_XREF=gi:7661547 /UG=Hs.5324 hypothetical protein /FL=gb:AF060224.1 gb:BC000932.2 gb:AF131802.1 gb:AF161510.1 gb:NM_015702.1 NM_015702 methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria MMADHC 27249 NM_015702 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009235 // cobalamin metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 217884_at NM_024662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024662.1 /DEF=Homo sapiens hypothetical protein FLJ10774; KIAA1709 protein (FLJ10774), mRNA. /FEA=mRNA /GEN=FLJ10774 /PROD=hypothetical protein FLJ12179 /DB_XREF=gi:13399321 /UG=Hs.71472 hypothetical protein FLJ10774; KIAA1709 protein /FL=gb:AL136882.1 gb:NM_024662.1 NM_024662 N-acetyltransferase 10 (GCN5-related) NAT10 55226 NM_001144030 /// NM_024662 /// XM_005252999 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217885_at NM_018085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018085.1 /DEF=Homo sapiens hypothetical protein FLJ10402 (FLJ10402), mRNA. /FEA=mRNA /GEN=FLJ10402 /PROD=hypothetical protein FLJ10402 /DB_XREF=gi:8922404 /UG=Hs.7579 hypothetical protein FLJ10402 /FL=gb:BC003604.1 gb:NM_018085.1 NM_018085 importin 9 IPO9 55705 NM_018085 /// XM_006711440 0006606 // protein import into nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0042393 // histone binding // inferred from sequence or structural similarity 217886_at BF213575 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF213575 /FEA=EST /DB_XREF=gi:11107161 /DB_XREF=est:601845379F1 /CLONE=IMAGE:4070610 /UG=Hs.79095 epidermal growth factor receptor pathway substrate 15 /FL=gb:NM_001981.1 gb:U07707.1 BF213575 epidermal growth factor receptor pathway substrate 15 EPS15 2060 NM_001159969 /// NM_001981 /// XM_005270618 /// XM_006710446 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016050 // vesicle organization // traceable author statement /// 0032456 // endocytic recycling // inferred by curator /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217887_s_at NM_001981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001981.1 /DEF=Homo sapiens epidermal growth factor receptor pathway substrate 15 (EPS15), mRNA. /FEA=mRNA /GEN=EPS15 /PROD=epidermal growth factor receptor pathwaysubstrate 15 /DB_XREF=gi:4503592 /UG=Hs.79095 epidermal growth factor receptor pathway substrate 15 /FL=gb:NM_001981.1 gb:U07707.1 NM_001981 epidermal growth factor receptor pathway substrate 15 EPS15 2060 NM_001159969 /// NM_001981 /// XM_005270618 /// XM_006710446 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016050 // vesicle organization // traceable author statement /// 0032456 // endocytic recycling // inferred by curator /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217888_s_at NM_018209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018209.1 /DEF=Homo sapiens hypothetical protein FLJ10767 (FLJ10767), mRNA. /FEA=mRNA /GEN=FLJ10767 /PROD=hypothetical protein FLJ10767 /DB_XREF=gi:8922651 /UG=Hs.25584 hypothetical protein FLJ10767 /FL=gb:NM_018209.1 NM_018209 ADP-ribosylation factor GTPase activating protein 1 ARFGAP1 55738 NM_001281482 /// NM_001281483 /// NM_001281484 /// NM_018209 /// NM_175609 /// NR_104022 /// NR_104023 /// XM_006723823 /// XM_006723824 /// XR_430304 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030660 // Golgi-associated vesicle membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217889_s_at NM_024843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024843.1 /DEF=Homo sapiens hypothetical protein FLJ23462 (FLJ23462), mRNA. /FEA=mRNA /GEN=FLJ23462 /PROD=hypothetical protein FLJ23462 /DB_XREF=gi:13376256 /UG=Hs.31297 duodenal cytochrome b /FL=gb:AL136693.1 gb:NM_024843.1 NM_024843 cytochrome b reductase 1 CYBRD1 79901 NM_001127383 /// NM_001256909 /// NM_024843 0006879 // cellular iron ion homeostasis // traceable author statement /// 0010039 // response to iron ion // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000293 // ferric-chelate reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016722 // oxidoreductase activity, oxidizing metal ions // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217890_s_at NM_018222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018222.1 /DEF=Homo sapiens alpha-parvin (PARVA), mRNA. /FEA=mRNA /GEN=PARVA /PROD=alpha-parvin /DB_XREF=gi:8922672 /UG=Hs.44077 alpha-parvin /FL=gb:AF237771.1 gb:NM_018222.1 NM_018222 parvin, alpha PARVA 55742 NM_018222 /// XM_005253015 0001525 // angiogenesis // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0070252 // actin-mediated cell contraction // inferred from sequence or structural similarity /// 0071670 // smooth muscle cell chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 217891_at NM_022744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022744.1 /DEF=Homo sapiens hypothetical protein FLJ13868 (FLJ13868), mRNA. /FEA=mRNA /GEN=FLJ13868 /PROD=hypothetical protein FLJ13868 /DB_XREF=gi:12232402 /UG=Hs.9003 hypothetical protein FLJ13868 /FL=gb:NM_022744.1 NM_022744 chromosome 16 open reading frame 58 C16orf58 64755 NM_022744 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217892_s_at NM_016357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016357.1 /DEF=Homo sapiens epithelial protein lost in neoplasm beta (EPLIN), mRNA. /FEA=mRNA /GEN=EPLIN /PROD=epithelial protein lost in neoplasm beta /DB_XREF=gi:7705372 /UG=Hs.10706 epithelial protein lost in neoplasm beta /FL=gb:AL136911.1 gb:BC001247.1 gb:AF198454.1 gb:NM_016357.1 NM_016357 LIM domain and actin binding 1 LIMA1 51474 NM_001113546 /// NM_001113547 /// NM_001243775 /// NM_016357 0030835 // negative regulation of actin filament depolymerization // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 217893_s_at NM_024595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024595.1 /DEF=Homo sapiens hypothetical protein FLJ12666 (FLJ12666), mRNA. /FEA=mRNA /GEN=FLJ12666 /PROD=hypothetical protein FLJ12666 /DB_XREF=gi:13375790 /UG=Hs.23767 hypothetical protein FLJ12666 /FL=gb:NM_024595.1 NM_024595 akirin 1 AKIRIN1 79647 NM_001136275 /// NM_024595 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 217894_at NM_016121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016121.1 /DEF=Homo sapiens NY-REN-45 antigen (LOC51133), mRNA. /FEA=mRNA /GEN=LOC51133 /PROD=NY-REN-45 antigen /DB_XREF=gi:7705836 /UG=Hs.239155 NY-REN-45 antigen /FL=gb:AF155110.1 gb:NM_016121.1 NM_016121 potassium channel tetramerization domain containing 3 KCTD3 51133 NM_016121 /// XM_005273156 /// XM_005273157 /// XM_005273158 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217895_at NM_017952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017952.1 /DEF=Homo sapiens hypothetical protein FLJ20758 (FLJ20758), mRNA. /FEA=mRNA /GEN=FLJ20758 /PROD=hypothetical protein FLJ20758 /DB_XREF=gi:8923669 /UG=Hs.274248 hypothetical protein FLJ20758 /FL=gb:NM_017952.1 NM_017952 pentatricopeptide repeat domain 3 PTCD3 55037 NM_017952 0006417 // regulation of translation // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 217896_s_at NM_024946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024946.1 /DEF=Homo sapiens hypothetical protein FLJ21799 (FLJ21799), mRNA. /FEA=mRNA /GEN=FLJ21799 /PROD=hypothetical protein FLJ21799 /DB_XREF=gi:13376428 /UG=Hs.285017 hypothetical protein FLJ21799 /FL=gb:NM_024946.1 NM_024946 family with sequence similarity 192, member A FAM192A 80011 NM_024946 /// XM_005256156 /// XM_005256157 /// XM_005256158 /// XM_005256159 /// XM_005256160 /// XM_005256161 /// XM_005256162 /// XM_005256163 /// XM_005256164 /// XM_005256165 /// XM_006721275 /// XM_006721276 0005634 // nucleus // inferred from direct assay 217897_at NM_022003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022003.1 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 6 (FXYD6), mRNA. /FEA=mRNA /GEN=FXYD6 /PROD=FXYD domain-containing ion transport regulator6 /DB_XREF=gi:11612654 /UG=Hs.3807 FXYD domain-containing ion transport regulator 6 /FL=gb:NM_022003.1 gb:AL136699.1 NM_022003 FXYD domain containing ion transport regulator 6 FXYD6 53826 NM_001164831 /// NM_001164832 /// NM_001164836 /// NM_001164837 /// NM_022003 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation 217898_at NM_020154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020154.1 /DEF=Homo sapiens chromosome 11 hypothetical protein ORF3 (LOC56851), mRNA. /FEA=mRNA /GEN=LOC56851 /PROD=chromosome 11 hypothetical protein ORF3 /DB_XREF=gi:9910345 /UG=Hs.4245 chromosome 11 hypothetical protein ORF3 /FL=gb:AF242729.1 gb:NM_020154.1 NM_020154 ER membrane protein complex subunit 7 EMC7 56851 NM_020154 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0072546 // ER membrane protein complex // inferred from direct assay 0017076 // purine nucleotide binding // non-traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 217899_at NM_017727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017727.1 /DEF=Homo sapiens hypothetical protein FLJ20254 (FLJ20254), mRNA. /FEA=mRNA /GEN=FLJ20254 /PROD=hypothetical protein FLJ20254 /DB_XREF=gi:8923227 /UG=Hs.15356 hypothetical protein FLJ20254 /FL=gb:BC002467.1 gb:NM_017727.1 NM_017727 transmembrane protein 214 TMEM214 54867 NM_001083590 /// NM_017727 /// XM_005264381 /// XM_005264382 /// XM_005264383 /// XM_006712036 /// XR_244942 /// XR_426985 0006915 // apoptotic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217900_at NM_018060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018060.1 /DEF=Homo sapiens hypothetical protein FLJ10326 (FLJ10326), mRNA. /FEA=mRNA /GEN=FLJ10326 /PROD=hypothetical protein FLJ10326 /DB_XREF=gi:8922355 /UG=Hs.262823 hypothetical protein FLJ10326 /FL=gb:NM_018060.1 NM_018060 isoleucyl-tRNA synthetase 2, mitochondrial IARS2 55699 NM_018060 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006428 // isoleucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004822 // isoleucine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 217901_at BF031829 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF031829 /FEA=EST /DB_XREF=gi:10739541 /DB_XREF=est:601557983F1 /CLONE=IMAGE:3827709 /UG=Hs.2631 desmoglein 2 /FL=gb:NM_001943.1 BF031829 desmoglein 2 DSG2 1829 NM_001943 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217902_s_at NM_004667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004667.2 /DEF=Homo sapiens hect domain and RLD 2 (HERC2), mRNA. /FEA=mRNA /GEN=HERC2 /PROD=hect domain and RLD 2 /DB_XREF=gi:5729867 /UG=Hs.266933 hect domain and RLD 2 /FL=gb:AF071172.3 gb:NM_004667.2 NM_004667 HECT and RLD domain containing E3 ubiquitin protein ligase 2 HERC2 8924 NM_004667 /// XM_005268276 /// XM_005268277 /// XM_006720726 /// XM_006720727 0006281 // DNA repair // inferred from direct assay /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032183 // SUMO binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 217903_at NM_013403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013403.1 /DEF=Homo sapiens zinedin (ZIN), mRNA. /FEA=mRNA /GEN=ZIN /PROD=zinedin /DB_XREF=gi:7019572 /UG=Hs.108665 zinedin /FL=gb:AF212940.1 gb:NM_013403.1 NM_013403 striatin, calmodulin binding protein 4 STRN4 29888 NM_001039877 /// NM_013403 /// XM_006723171 /// XM_006723172 /// XM_006723173 /// XM_006723174 /// XM_006723175 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 217904_s_at NM_012104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012104.1 /DEF=Homo sapiens beta-site APP-cleaving enzyme (BACE), mRNA. /FEA=mRNA /GEN=BACE /PROD=beta-site APP-cleaving enzyme /DB_XREF=gi:6912265 /UG=Hs.49349 beta-site APP-cleaving enzyme /FL=gb:AF190725.1 gb:AF200343.1 gb:AF201468.1 gb:AF204943.1 gb:NM_012104.1 NM_012104 beta-site APP-cleaving enzyme 1 BACE1 23621 NM_001207048 /// NM_001207049 /// NM_012104 /// NM_138971 /// NM_138972 /// NM_138973 0006508 // proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // traceable author statement /// 0050435 // beta-amyloid metabolic process // inferred from direct assay 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008798 // beta-aspartyl-peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 217905_at NM_024834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024834.1 /DEF=Homo sapiens hypothetical protein FLJ13081 (FLJ13081), mRNA. /FEA=mRNA /GEN=FLJ13081 /PROD=hypothetical protein FLJ13081 /DB_XREF=gi:13376242 /UG=Hs.180638 hypothetical protein FLJ13081 /FL=gb:BC004183.1 gb:NM_024834.1 NM_024834 minichromosome maintenance complex binding protein MCMBP 79892 NM_001256378 /// NM_001256379 /// NM_024834 /// XM_005270157 0000084 // mitotic S phase // inferred from mutant phenotype /// 0000084 // mitotic S phase // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 217906_at NM_014315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014315.1 /DEF=Homo sapiens host cell factor homolog (LCP), mRNA. /FEA=mRNA /GEN=LCP /PROD=host cell factor homolog /DB_XREF=gi:7657300 /UG=Hs.20597 host cell factor homolog /FL=gb:BC002335.1 gb:AF113131.1 gb:NM_014315.1 gb:AF244137.1 NM_014315 kelch domain containing 2 KLHDC2 23588 NM_014315 /// XM_006720094 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 217907_at NM_014161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014161.1 /DEF=Homo sapiens HSPC071 protein (HSPC071), mRNA. /FEA=mRNA /GEN=HSPC071 /PROD=HSPC071 protein /DB_XREF=gi:7661777 /UG=Hs.23038 HSPC071 protein /FL=gb:AL136633.1 gb:BC001623.1 gb:AF161556.1 gb:NM_014161.1 NM_014161 mitochondrial ribosomal protein L18 MRPL18 29074 NM_014161 /// XM_006715466 0006412 // translation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0035928 // rRNA import into mitochondrion // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0008097 // 5S rRNA binding // inferred from direct assay 217908_s_at NM_018442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018442.1 /DEF=Homo sapiens PC326 protein (PC326), mRNA. /FEA=mRNA /GEN=PC326 /PROD=PC326 protein /DB_XREF=gi:8923955 /UG=Hs.279882 PC326 protein /FL=gb:AL136738.1 gb:AF150734.1 gb:NM_018442.1 NM_018442 DDB1 and CUL4 associated factor 6 DCAF6 55827 NM_001017977 /// NM_001198956 /// NM_001198957 /// NM_018442 /// XM_005245331 /// XM_005245332 /// XM_005245333 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 217909_s_at BF056105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056105 /FEA=EST /DB_XREF=gi:10810001 /DB_XREF=est:7j87a03.x1 /CLONE=IMAGE:3393388 /UG=Hs.78185 MAX-like bHLHZIP protein /FL=gb:AF213668.1 gb:AF203978.1 gb:NM_013383.1 BF056105 MLX, MAX dimerization protein MLX 6945 NM_170607 /// NM_198204 /// NM_198205 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 217910_x_at NM_013383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013383.1 /DEF=Homo sapiens MAX-like bHLHZIP protein (MLX), mRNA. /FEA=mRNA /GEN=MLX /PROD=MAX-like bHLHZIP protein /DB_XREF=gi:7019460 /UG=Hs.78185 MAX-like bHLHZIP protein /FL=gb:AF213668.1 gb:AF203978.1 gb:NM_013383.1 NM_013383 MLX, MAX dimerization protein MLX 6945 NM_170607 /// NM_198204 /// NM_198205 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 217911_s_at NM_004281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004281.1 /DEF=Homo sapiens BCL2-associated athanogene 3 (BAG3), mRNA. /FEA=mRNA /GEN=BAG3 /PROD=BCL2-associated athanogene 3 /DB_XREF=gi:6631072 /UG=Hs.15259 BCL2-associated athanogene 3 /FL=gb:AF095193.2 gb:NM_004281.1 gb:AF127139.1 gb:AF071218.2 NM_004281 BCL2-associated athanogene 3 BAG3 9531 NM_004281 /// XM_005270287 0006457 // protein folding // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0050821 // protein stabilization // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 217912_at NM_022156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022156.1 /DEF=Homo sapiens PP3111 protein (PP3111), mRNA. /FEA=mRNA /GEN=PP3111 /PROD=PP3111 protein /DB_XREF=gi:11545903 /UG=Hs.168541 PP3111 protein /FL=gb:AF202637.1 gb:NM_022156.1 NM_022156 dihydrouridine synthase 1-like (S. cerevisiae) DUS1L 64118 NM_022156 /// XM_005256393 /// XM_005256394 /// XM_006722288 /// XM_006722289 0002943 // tRNA dihydrouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 217913_at NM_013245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013245.1 /DEF=Homo sapiens vacuolar sorting protein 4 (VPS4), mRNA. /FEA=mRNA /GEN=VPS4 /PROD=vacuolar sorting protein 4 /DB_XREF=gi:7019568 /UG=Hs.234839 vacuolar sorting protein 4 /FL=gb:AF159063.1 gb:AF112215.1 gb:NM_013245.1 NM_013245 vacuolar protein sorting 4 homolog A (S. cerevisiae) VPS4A 27183 NM_013245 0000910 // cytokinesis // inferred from direct assay /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009838 // abscission // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031565 // cytokinesis checkpoint // inferred from mutant phenotype /// 0032466 // negative regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0000815 // ESCRT III complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // non-traceable author statement 217914_at NM_017901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017901.1 /DEF=Homo sapiens two-pore channel 1, homolog (KIAA1169), mRNA. /FEA=mRNA /GEN=KIAA1169 /PROD=two-pore channel 1, homolog /DB_XREF=gi:8923566 /UG=Hs.26440 two-pore channel 1, homolog /FL=gb:NM_017901.1 NM_017901 two pore segment channel 1 TPCN1 53373 NM_001143819 /// NM_017901 /// XM_005253905 /// XM_005253906 /// XM_006719465 /// XR_243016 /// XR_243017 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // not recorded /// 0034220 // ion transmembrane transport // not recorded /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0072345 // NAADP-sensitive calcium-release channel activity // inferred from direct assay 217915_s_at NM_016304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016304.1 /DEF=Homo sapiens 60S ribosomal protein L30 isolog (LOC51187), mRNA. /FEA=mRNA /GEN=LOC51187 /PROD=60S ribosomal protein L30 isolog /DB_XREF=gi:10047101 /UG=Hs.284162 60S ribosomal protein L30 isolog /FL=gb:NM_016304.1 gb:AF060926.1 gb:AF212226.1 gb:BC005344.1 gb:AF201949.1 gb:AF165521.1 NM_016304 ribosomal L24 domain containing 1 RSL24D1 51187 NM_016304 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 217916_s_at NM_016623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016623.1 /DEF=Homo sapiens hypothetical protein (BM-009), mRNA. /FEA=mRNA /GEN=BM-009 /PROD=hypothetical protein /DB_XREF=gi:7705303 /UG=Hs.92918 hypothetical protein /FL=gb:BC003599.1 gb:AF208851.1 gb:NM_016623.1 NM_016623 family with sequence similarity 49, member B FAM49B 51571 NM_001256763 /// NM_016623 /// NR_046359 /// NR_046360 /// NR_046361 /// XM_005250966 /// XM_006716582 /// XM_006716583 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 217917_s_at NM_014183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014183.1 /DEF=Homo sapiens HSPC162 protein (HSPC162), mRNA. /FEA=mRNA /GEN=HSPC162 /PROD=HSPC162 protein /DB_XREF=gi:7661821 /UG=Hs.100002 HSPC162 protein /FL=gb:BC002481.1 gb:AY026513.1 gb:AF161511.1 gb:NM_014183.1 gb:AF165516.1 NM_014183 dynein, light chain, roadblock-type 1 DYNLRB1 83658 NM_001281727 /// NM_001281728 /// NM_001281729 /// NM_014183 /// NM_177953 /// NR_104032 /// XM_005260568 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0007632 // visual behavior // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005868 // cytoplasmic dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 217918_at NM_014183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014183.1 /DEF=Homo sapiens HSPC162 protein (HSPC162), mRNA. /FEA=mRNA /GEN=HSPC162 /PROD=HSPC162 protein /DB_XREF=gi:7661821 /UG=Hs.100002 HSPC162 protein /FL=gb:BC002481.1 gb:AY026513.1 gb:AF161511.1 gb:NM_014183.1 gb:AF165516.1 NM_014183 dynein, light chain, roadblock-type 1 DYNLRB1 83658 NM_001281727 /// NM_001281728 /// NM_001281729 /// NM_014183 /// NM_177953 /// NR_104032 /// XM_005260568 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0007632 // visual behavior // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005868 // cytoplasmic dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 217919_s_at BE782148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE782148 /FEA=EST /DB_XREF=gi:10203346 /DB_XREF=est:601467749F1 /CLONE=IMAGE:3870636 /UG=Hs.112110 PTD007 protein /FL=gb:AL136659.1 gb:AF078860.1 gb:AF151038.1 gb:NM_014050.1 BE782148 mitochondrial ribosomal protein L42 MRPL42 28977 NM_014050 /// NM_172177 /// NM_172178 /// NR_038159 /// NR_038160 /// NR_038161 0006412 // translation // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 217920_at H97940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H97940 /FEA=EST /DB_XREF=gi:1118825 /DB_XREF=est:yx04d03.s1 /CLONE=IMAGE:260741 /UG=Hs.239114 mannosidase, alpha, class 1A, member 2 /FL=gb:AF027156.1 gb:NM_006699.1 H97940 mannosidase, alpha, class 1A, member 2 MAN1A2 10905 NM_006699 /// XM_006710302 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 217921_at BE543064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE543064 /FEA=EST /DB_XREF=gi:9771709 /DB_XREF=est:601068994F1 /CLONE=IMAGE:3455374 /UG=Hs.239114 mannosidase, alpha, class 1A, member 2 /FL=gb:AF027156.1 gb:NM_006699.1 BE543064 mannosidase, alpha, class 1A, member 2 MAN1A2 10905 NM_006699 /// XM_006710302 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 217922_at AL157902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157902 /DEF=Human DNA sequence from clone RP4-675C20 on chromosome 1p13.2. Contains the 3 end of the MAN1A2 gene for mannosidase alpha 1A2, a pseudogene similar to predicted fly, worm and yeast genes, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:9581579 /UG=Hs.239114 mannosidase, alpha, class 1A, member 2 /FL=gb:AF027156.1 gb:NM_006699.1 AL157902 mannosidase, alpha, class 1A, member 2 MAN1A2 10905 NM_006699 /// XM_006710302 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 217923_at NM_012392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012392.1 /DEF=Homo sapiens PEF protein with a long N-terminal hydrophobic domain (peflin) (PEF), mRNA. /FEA=mRNA /GEN=PEF /PROD=peflin /DB_XREF=gi:6912581 /UG=Hs.241531 peflin /FL=gb:BC002773.1 gb:AB018357.1 gb:AB026628.1 gb:NM_012392.1 NM_012392 penta-EF-hand domain containing 1 PEF1 553115 NM_012392 /// NR_033686 /// NR_033688 0006508 // proteolysis // not recorded /// 0051592 // response to calcium ion // inferred from physical interaction 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 217924_at AL523965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL523965 /FEA=EST /DB_XREF=gi:12787458 /DB_XREF=est:AL523965 /CLONE=CS0DC003YN21 (5 prime) /UG=Hs.25999 hypothetical protein FLJ22195 /FL=gb:NM_022758.1 AL523965 chromosome 6 open reading frame 106 C6orf106 64771 NM_022758 /// NM_024294 /// XM_005249298 0005515 // protein binding // inferred from electronic annotation 217925_s_at NM_022758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022758.1 /DEF=Homo sapiens hypothetical protein FLJ22195 (FLJ22195), mRNA. /FEA=mRNA /GEN=FLJ22195 /PROD=hypothetical protein FLJ22195 /DB_XREF=gi:12232426 /UG=Hs.25999 hypothetical protein FLJ22195 /FL=gb:NM_022758.1 NM_022758 chromosome 6 open reading frame 106 C6orf106 64771 NM_022758 /// NM_024294 /// XM_005249298 0005515 // protein binding // inferred from electronic annotation 217926_at NM_014047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014047.1 /DEF=Homo sapiens HSPC023 protein (HSPC023), mRNA. /FEA=mRNA /GEN=HSPC023 /PROD=HSPC023 protein /DB_XREF=gi:7661741 /UG=Hs.279945 HSPC023 protein /FL=gb:AF078852.1 gb:NM_014047.1 NM_014047 chromosome 19 open reading frame 53 C19orf53 28974 NM_014047 217927_at NM_014041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014041.1 /DEF=Homo sapiens HSPC033 protein (HSPC033), mRNA. /FEA=mRNA /GEN=HSPC033 /PROD=HSPC033 protein /DB_XREF=gi:7661745 /UG=Hs.11125 HSPC033 protein /FL=gb:BC000884.1 gb:AF092138.1 gb:NM_014041.1 NM_014041 signal peptidase complex subunit 1 homolog (S. cerevisiae) SPCS1 28972 NM_014041 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation 217928_s_at NM_018312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018312.2 /DEF=Homo sapiens chromosome 11 open reading frame 23 (C11ORF23), mRNA. /FEA=mRNA /GEN=C11ORF23 /PROD=sporulation-induced transcript 4-associatedprotein /DB_XREF=gi:13489082 /UG=Hs.180817 chromosome 11 open reading frame 23 /FL=gb:AF264779.1 gb:NM_018312.2 NM_018312 protein phosphatase 6, regulatory subunit 3 PPP6R3 55291 NM_001164160 /// NM_001164161 /// NM_001164162 /// NM_001164163 /// NM_001164164 /// NM_018312 /// XM_005274081 /// XM_006718608 /// XM_006718609 /// XM_006718610 /// XM_006718611 /// XM_006718612 /// XM_006718613 /// XM_006718614 /// XM_006718615 /// XM_006718616 /// XM_006718617 /// XM_006718618 /// XM_006718619 /// XM_006718620 /// XM_006718621 /// XM_006718622 /// XM_006718623 /// XM_006718624 /// XM_006718625 /// XM_006718626 /// XM_006718627 /// XM_006718628 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction 217929_s_at NM_024874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024874.1 /DEF=Homo sapiens hypothetical protein FLJ14225 (FLJ14225), mRNA. /FEA=mRNA /GEN=FLJ14225 /PROD=hypothetical protein FLJ14225 /DB_XREF=gi:13376311 /UG=Hs.209065 hypothetical protein FLJ14225 /FL=gb:NM_024874.1 NM_024874 KIAA0319-like KIAA0319L 79932 NM_024874 /// NM_182686 /// XM_006710907 /// XM_006710908 /// XM_006710909 /// XM_006710910 /// XM_006710911 /// XR_246296 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217930_s_at NM_019009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019009.1 /DEF=Homo sapiens TOLLIP protein (LOC54472), mRNA. /FEA=mRNA /GEN=LOC54472 /PROD=TOLLIP protein /DB_XREF=gi:9506854 /UG=Hs.25413 TOLLIP protein /FL=gb:AL136835.1 gb:BC004420.1 gb:NM_019009.1 NM_019009 toll interacting protein TOLLIP 54472 NM_019009 0002376 // immune system process // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007165 // signal transduction // inferred from physical interaction /// 0007267 // cell-cell signaling // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0036010 // protein localization to endosome // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0045321 // leukocyte activation // non-traceable author statement 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0016604 // nuclear body // inferred from electronic annotation /// 0045092 // interleukin-18 receptor complex // non-traceable author statement /// 0045323 // interleukin-1 receptor complex // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005150 // interleukin-1, Type I receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032183 // SUMO binding // inferred from electronic annotation /// 0035325 // Toll-like receptor binding // inferred from physical interaction 217931_at BC004423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004423.1 /DEF=Homo sapiens, clone MGC:3530, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3530) /DB_XREF=gi:13325207 /UG=Hs.56828 trinucleotide repeat containing 5 /FL=gb:BC004423.1 gb:U80744.1 gb:NM_006586.1 BC004423 canopy FGF signaling regulator 3 CNPY3 10695 NM_006586 /// NM_183010 /// XM_005248815 /// XM_005248817 /// XM_005248818 /// XM_006714967 /// XM_006714968 /// XR_427823 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005102 // receptor binding // inferred from electronic annotation 217932_at NM_015971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015971.1 /DEF=Homo sapiens 30S ribosomal protein S7 homolog (LOC51081), mRNA. /FEA=mRNA /GEN=LOC51081 /PROD=30S ribosomal protein S7 homolog /DB_XREF=gi:7705737 /UG=Hs.71787 30S ribosomal protein S7 homolog /FL=gb:BC000241.1 gb:AF077042.1 gb:NM_015971.1 NM_015971 mitochondrial ribosomal protein S7 MRPS7 51081 NM_015971 /// XM_005257424 0006412 // translation // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from sequence or structural similarity /// 0003735 // structural constituent of ribosome // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 217933_s_at NM_015907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015907.1 /DEF=Homo sapiens leucine aminopeptidase (LOC51056), mRNA. /FEA=mRNA /GEN=LOC51056 /PROD=leucine aminopeptidase /DB_XREF=gi:7705687 /UG=Hs.182579 leucine aminopeptidase /FL=gb:AF061738.1 gb:NM_015907.1 NM_015907 leucine aminopeptidase 3 LAP3 51056 NM_015907 0006508 // proteolysis // non-traceable author statement /// 0019538 // protein metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // non-traceable author statement /// 0004177 // aminopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217934_x_at NM_005861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005861.1 /DEF=Homo sapiens STIP1 homology and U-Box containing protein 1 (STUB1), mRNA. /FEA=mRNA /GEN=STUB1 /PROD=serologically defined colon cancer antigen 7 /DB_XREF=gi:5031962 /UG=Hs.25197 STIP1 homology and U-Box containing protein 1 /FL=gb:AF039689.1 gb:AF129085.1 gb:NM_005861.1 NM_005861 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase STUB1 10273 NM_001293197 /// NM_005861 0000209 // protein polyubiquitination // inferred from direct assay /// 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031943 // regulation of glucocorticoid metabolic process // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051604 // protein maturation // traceable author statement /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from direct assay /// 0090035 // positive regulation of chaperone-mediated protein complex assembly // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0031371 // ubiquitin conjugating enzyme complex // traceable author statement /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0030674 // protein binding, bridging // traceable author statement /// 0030911 // TPR domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from direct assay /// 0051879 // Hsp90 protein binding // inferred from direct assay 217935_s_at NM_018244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018244.1 /DEF=Homo sapiens hypothetical protein FLJ10850 (FLJ10850), mRNA. /FEA=mRNA /GEN=FLJ10850 /PROD=hypothetical protein FLJ10850 /DB_XREF=gi:8922713 /UG=Hs.26676 hypothetical protein FLJ10850 /FL=gb:NM_018244.1 NM_018244 ubiquinol-cytochrome c reductase complex assembly factor 1 UQCC1 55245 NM_001184977 /// NM_018244 /// NM_199487 /// NM_199513 /// XM_006723814 0005739 // mitochondrion // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 217936_at AW044631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW044631 /FEA=EST /DB_XREF=gi:5905160 /DB_XREF=est:wy78c11.x1 /CLONE=IMAGE:2554676 /UG=Hs.267831 Rho GTPase activating protein 5 /FL=gb:NM_001173.1 gb:U17032.1 AW044631 Rho GTPase activating protein 5 ARHGAP5 394 NM_001030055 /// NM_001173 /// XM_005267635 /// XM_005267636 /// XR_245684 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction 217937_s_at NM_016596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016596.2 /DEF=Homo sapiens histone deacetylase 7A (HDAC7), transcript variant 2, mRNA. /FEA=mRNA /GEN=HDAC7 /PROD=histone deacetylase 7A, isoform b /DB_XREF=gi:13259523 /UG=Hs.275438 histone deacetylase 7A /FL=gb:NM_016596.2 gb:AF239243.1 NM_016596 histone deacetylase 7 HDAC7 51564 NM_001098416 /// NM_015401 /// NM_016596 /// XM_005268968 /// XM_006719454 /// XM_006719455 /// XM_006719456 /// XM_006719457 /// XM_006719458 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 217938_s_at NM_020122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020122.1 /DEF=Homo sapiens potassium channel modulatory factor (DKFZP434L1021), mRNA. /FEA=mRNA /GEN=DKFZP434L1021 /PROD=potassium channel modulatory factor /DB_XREF=gi:10047127 /UG=Hs.5392 potassium channel modulatory factor /FL=gb:NM_020122.1 gb:BC000178.2 NM_020122 potassium channel modulatory factor 1 KCMF1 56888 NM_020122 /// XM_006712052 0008152 // metabolic process // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217939_s_at NM_017657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017657.1 /DEF=Homo sapiens hypothetical protein FLJ20080 (FLJ20080), mRNA. /FEA=mRNA /GEN=FLJ20080 /PROD=hypothetical protein FLJ20080 /DB_XREF=gi:8923087 /UG=Hs.7942 hypothetical protein FLJ20080 /FL=gb:NM_017657.1 NM_017657 aftiphilin AFTPH 54812 NM_001002243 /// NM_017657 /// NM_203437 /// XM_005264380 /// XR_244940 /// XR_244941 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030121 // AP-1 adaptor complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0030276 // clathrin binding // inferred from direct assay 217940_s_at NM_018210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018210.1 /DEF=Homo sapiens hypothetical protein FLJ10769 (FLJ10769), mRNA. /FEA=mRNA /GEN=FLJ10769 /PROD=hypothetical protein FLJ10769 /DB_XREF=gi:8922653 /UG=Hs.8083 hypothetical protein FLJ10769 /FL=gb:AF151071.1 gb:NM_018210.1 NM_018210 carbohydrate kinase domain containing CARKD 55739 NM_001242881 /// NM_001242882 /// NM_001242883 /// NM_018210 /// NR_040103 /// NR_040104 0046496 // nicotinamide nucleotide metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0047453 // ATP-dependent NAD(P)H-hydrate dehydratase activity // inferred from electronic annotation 217941_s_at NM_018695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018695.1 /DEF=Homo sapiens erbb2-interacting protein ERBIN (LOC55914), mRNA. /FEA=mRNA /GEN=LOC55914 /PROD=erbb2-interacting protein ERBIN /DB_XREF=gi:8923908 /UG=Hs.8117 erbb2-interacting protein ERBIN /FL=gb:AF263744.1 gb:NM_018695.1 NM_018695 erbb2 interacting protein ERBB2IP 55914 NM_001006600 /// NM_001253697 /// NM_001253698 /// NM_001253699 /// NM_001253701 /// NM_018695 /// XM_005248554 /// XM_005248555 /// XM_005248556 /// XM_006714660 0006605 // protein targeting // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0045175 // basal protein localization // non-traceable author statement /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // non-traceable author statement 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation 0005176 // ErbB-2 class receptor binding // traceable author statement /// 0005178 // integrin binding // inferred from physical interaction /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 217942_at NM_021821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021821.1 /DEF=Homo sapiens MDS023 protein (MDS023), mRNA. /FEA=mRNA /GEN=MDS023 /PROD=MDS023 protein /DB_XREF=gi:11141894 /UG=Hs.10724 MDS023 protein /FL=gb:AF182422.1 gb:NM_021821.1 NM_021821 mitochondrial ribosomal protein S35 MRPS35 60488 NM_001190864 /// NM_021821 0042769 // DNA damage response, detection of DNA damage // non-traceable author statement /// 0043043 // peptide biosynthetic process // inferred by curator 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from sequence or structural similarity /// 0005763 // mitochondrial small ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 217943_s_at NM_018067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018067.1 /DEF=Homo sapiens hypothetical protein FLJ10350 (FLJ10350), mRNA. /FEA=mRNA /GEN=FLJ10350 /PROD=hypothetical protein FLJ10350 /DB_XREF=gi:8922367 /UG=Hs.177596 hypothetical protein FLJ10350 /FL=gb:BC003083.1 gb:NM_018067.1 NM_018067 MAP7 domain containing 1 MAP7D1 55700 NM_001286365 /// NM_001286366 /// NM_018067 /// XM_005271024 /// XM_005271025 /// XM_005271027 /// XM_006710759 /// XM_006710760 /// XM_006710761 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 217944_at NM_017739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017739.1 /DEF=Homo sapiens hypothetical protein FLJ20277 (FLJ20277), mRNA. /FEA=mRNA /GEN=FLJ20277 /PROD=hypothetical protein FLJ20277 /DB_XREF=gi:8923252 /UG=Hs.183860 hypothetical protein FLJ20277 /FL=gb:BC001471.1 gb:NM_017739.1 NM_017739 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) POMGNT1 55624 NM_001243766 /// NM_001290129 /// NM_001290130 /// NM_017739 /// XM_005271010 /// XM_006710755 /// XM_006710756 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047223 // beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity // inferred from direct assay 217945_at NM_025238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025238.1 /DEF=Homo sapiens BTB (POZ) domain containing 1 (BTBD1), mRNA. /FEA=mRNA /GEN=BTBD1 /PROD=BTB (POZ) domain containing 1 /DB_XREF=gi:13376847 /UG=Hs.21332 BTB (POZ) domain containing 1 /FL=gb:AL136853.1 gb:AF257241.1 gb:NM_025238.1 gb:AF355402.1 NM_025238 BTB (POZ) domain containing 1 BTBD1 53339 NM_001011885 /// NM_025238 /// XM_006720573 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043393 // regulation of protein binding // non-traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217946_s_at NM_016402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016402.1 /DEF=Homo sapiens hypothetical protein (HSPC140), mRNA. /FEA=mRNA /GEN=HSPC140 /PROD=hypothetical protein /DB_XREF=gi:7705472 /UG=Hs.279868 hypothetical protein /FL=gb:BC003611.1 gb:AF161489.1 gb:NM_016402.1 NM_016402 SUMO1 activating enzyme subunit 1 SAE1 10055 NM_001145713 /// NM_001145714 /// NM_005500 /// NR_027280 /// XM_006722963 /// XM_006722964 /// XM_006722965 0006464 // cellular protein modification process // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0019950 // SMT3-dependent protein catabolic process // not recorded /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from direct assay /// 0008047 // enzyme activator activity // traceable author statement /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019948 // SUMO activating enzyme activity // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // traceable author statement 217947_at NM_017801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017801.1 /DEF=Homo sapiens hypothetical protein FLJ20396 (FLJ20396), mRNA. /FEA=mRNA /GEN=FLJ20396 /PROD=hypothetical protein FLJ20396 /DB_XREF=gi:8923369 /UG=Hs.283685 hypothetical protein FLJ20396 /FL=gb:BC002797.1 gb:NM_017801.1 NM_017801 CKLF-like MARVEL transmembrane domain containing 6 CMTM6 54918 NM_017801 0006935 // chemotaxis // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation 217948_at NM_015582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015582.1 /DEF=Homo sapiens DKFZP564B147 protein (DKFZP564B147), mRNA. /FEA=mRNA /GEN=DKFZP564B147 /PROD=DKFZP564B147 protein /DB_XREF=gi:7661599 /UG=Hs.284266 DKFZP564B147 protein /FL=gb:BC000393.1 gb:NM_015582.1 NM_015582 family with sequence similarity 127, member B FAM127B 26071 NM_001078172 /// NM_001134321 /// NM_015582 /// NR_002732 217949_s_at NM_024006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024006.1 /DEF=Homo sapiens hypothetical protein IMAGE3455200 (IMAGE3455200), mRNA. /FEA=mRNA /GEN=IMAGE3455200 /PROD=hypothetical protein IMAGE3455200 /DB_XREF=gi:13124769 /UG=Hs.324844 hypothetical protein IMAGE3455200 /FL=gb:BC002911.1 gb:NM_024006.1 NM_024006 vitamin K epoxide reductase complex, subunit 1 VKORC1 79001 NM_024006 /// NM_206824 0007596 // blood coagulation // inferred from mutant phenotype /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0017187 // peptidyl-glutamic acid carboxylation // inferred from mutant phenotype /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0042373 // vitamin K metabolic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060348 // bone development // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047057 // vitamin-K-epoxide reductase (warfarin-sensitive) activity // inferred from direct assay /// 0048038 // quinone binding // inferred from electronic annotation 217950_at NM_015953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015953.1 /DEF=Homo sapiens CGI-25 protein (LOC51070), mRNA. /FEA=mRNA /GEN=LOC51070 /PROD=CGI-25 protein /DB_XREF=gi:7705715 /UG=Hs.7236 CGI-25 protein /FL=gb:AF132959.1 gb:NM_015953.1 NM_015953 nitric oxide synthase interacting protein NOSIP 51070 NM_001270960 /// NM_015953 /// XM_005258964 /// XM_006723235 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 217951_s_at AW189430 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW189430 /FEA=EST /DB_XREF=gi:6463892 /DB_XREF=est:xl06d10.x1 /CLONE=IMAGE:2675443 /UG=Hs.78893 KIAA0244 protein /FL=gb:AF091622.1 gb:NM_015153.1 AW189430 PHD finger protein 3 PHF3 23469 NM_001290259 /// NM_001290260 /// NM_015153 /// XM_005248701 /// XM_005248702 /// XM_005248703 /// XM_006715426 /// XM_006715427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217952_x_at BF430956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF430956 /FEA=EST /DB_XREF=gi:11443104 /DB_XREF=est:7o18h12.x1 /CLONE=IMAGE:3574535 /UG=Hs.78893 KIAA0244 protein /FL=gb:AF091622.1 gb:NM_015153.1 BF430956 PHD finger protein 3 PHF3 23469 NM_001290259 /// NM_001290260 /// NM_015153 /// XM_005248701 /// XM_005248702 /// XM_005248703 /// XM_006715426 /// XM_006715427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217953_at AL050329 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050329 /DEF=Human DNA sequence from clone RP1-22I17 on chromosome 6q11.1-12. Contains the 3 end of the gene KIAA0244, the 3 end of the gene for a novel protein with EGF-like and laminin G domains, ESTs, STSs and GSSs /FEA=mRNA_1 /DB_XREF=gi:8977876 /UG=Hs.78893 KIAA0244 protein /FL=gb:AF091622.1 gb:NM_015153.1 AL050329 PHD finger protein 3 PHF3 23469 NM_001290259 /// NM_001290260 /// NM_015153 /// XM_005248701 /// XM_005248702 /// XM_005248703 /// XM_006715426 /// XM_006715427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217954_s_at NM_015153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015153.1 /DEF=Homo sapiens KIAA0244 protein (KIAA0244), mRNA. /FEA=mRNA /GEN=KIAA0244 /PROD=KIAA0244 protein /DB_XREF=gi:7662017 /UG=Hs.78893 KIAA0244 protein /FL=gb:AF091622.1 gb:NM_015153.1 NM_015153 PHD finger protein 3 PHF3 23469 NM_001290259 /// NM_001290260 /// NM_015153 /// XM_005248701 /// XM_005248702 /// XM_005248703 /// XM_006715426 /// XM_006715427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217955_at NM_015367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015367.1 /DEF=Homo sapiens MIL1 protein (MIL1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MIL1 /PROD=MIL1 protein /DB_XREF=gi:7662505 /UG=Hs.10267 MIL1 protein /FL=gb:AF325209.1 gb:AF146568.1 gb:NM_015367.1 NM_015367 BCL2-like 13 (apoptosis facilitator) BCL2L13 23786 NM_001270726 /// NM_001270727 /// NM_001270728 /// NM_001270729 /// NM_001270730 /// NM_001270731 /// NM_001270732 /// NM_001270733 /// NM_001270734 /// NM_001270735 /// NM_015367 /// NR_073068 /// NR_073069 /// XM_006724075 /// XM_006724076 /// XR_430391 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement 217956_s_at NM_021204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021204.1 /DEF=Homo sapiens E-1 enzyme (MASA), mRNA. /FEA=mRNA /GEN=MASA /PROD=E-1 enzyme /DB_XREF=gi:10864016 /UG=Hs.18442 E-1 enzyme /FL=gb:NM_021204.1 gb:AF113125.1 NM_021204 enolase-phosphatase 1 ENOPH1 58478 NM_001292017 /// NM_021204 /// NR_120457 /// XM_005263168 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from direct assay /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043874 // acireductone synthase activity // inferred from direct assay /// 0043874 // acireductone synthase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217957_at NM_013242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013242.1 /DEF=Homo sapiens similar to mouse Glt3 or D. malanogaster transcription factor IIB (AF093680), mRNA. /FEA=mRNA /GEN=AF093680 /PROD=similar to mouse Glt3 or D. malanogastertranscription factor IIB /DB_XREF=gi:8392874 /UG=Hs.279818 similar to mouse Glt3 or D. malanogaster transcription factor IIB /FL=gb:BC005152.1 gb:AF093680.1 gb:NM_013242.1 NM_013242 chromosome 16 open reading frame 80 C16orf80 29105 NM_013242 0007275 // multicellular organismal development // traceable author statement 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 217958_at NM_016146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016146.1 /DEF=Homo sapiens PTD009 protein (PTD009), mRNA. /FEA=mRNA /GEN=PTD009 /PROD=PTD009 protein /DB_XREF=gi:7706666 /UG=Hs.279901 PTD009 protein /FL=gb:AF151862.1 gb:AF078862.1 gb:AF161520.1 gb:NM_016146.1 NM_016146 microRNA 3656 /// trafficking protein particle complex 4 MIR3656 /// TRAPPC4 51399 /// 100500840 NM_016146 /// NR_037429 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0030008 // TRAPP complex // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217959_s_at NM_016146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016146.1 /DEF=Homo sapiens PTD009 protein (PTD009), mRNA. /FEA=mRNA /GEN=PTD009 /PROD=PTD009 protein /DB_XREF=gi:7706666 /UG=Hs.279901 PTD009 protein /FL=gb:AF151862.1 gb:AF078862.1 gb:AF161520.1 gb:NM_016146.1 NM_016146 microRNA 3656 /// trafficking protein particle complex 4 MIR3656 /// TRAPPC4 51399 /// 100500840 NM_016146 /// NR_037429 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0030008 // TRAPP complex // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 217960_s_at NM_020243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020243.1 /DEF=Homo sapiens mitochondrial import receptor Tom22 (LOC56993), mRNA. /FEA=mRNA /GEN=LOC56993 /PROD=mitochondrial import receptor Tom22 /DB_XREF=gi:9910381 /UG=Hs.285005 mitochondrial import receptor Tom22 /FL=gb:AB041906.1 gb:AB040119.1 gb:NM_020243.1 NM_020243 translocase of outer mitochondrial membrane 22 homolog (yeast) TOMM22 56993 NM_020243 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // inferred from sequence or structural similarity /// 0008320 // protein transmembrane transporter activity // traceable author statement 217961_at NM_017875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017875.1 /DEF=Homo sapiens hypothetical protein FLJ20551 (FLJ20551), mRNA. /FEA=mRNA /GEN=FLJ20551 /PROD=hypothetical protein FLJ20551 /DB_XREF=gi:8923519 /UG=Hs.7994 hypothetical protein FLJ20551 /FL=gb:NM_017875.1 NM_017875 solute carrier family 25, member 38 SLC25A38 54977 NM_017875 /// XM_006713214 0006783 // heme biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 217962_at NM_018648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018648.1 /DEF=Homo sapiens nucleolar protein family A, member 3 (HACA small nucleolar RNPs) (NOLA3), mRNA. /FEA=mRNA /GEN=NOLA3 /PROD=nucleolar protein family A, member 3 (HACAsmall nucleolar RNPs) /DB_XREF=gi:8923941 /UG=Hs.14317 nucleolar protein family A, member 3 (HACA small nucleolar RNPs) /FL=gb:AB043104.1 gb:NM_018648.1 NM_018648 NOP10 ribonucleoprotein NOP10 55505 NM_018648 0001522 // pseudouridine synthesis // non-traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005732 // small nucleolar ribonucleoprotein complex // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0072588 // box H/ACA RNP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from electronic annotation 217963_s_at NM_014380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014380.1 /DEF=Homo sapiens p75NTR-associated cell death executor; ovarian granulosa cell protein (13kD) (DXS6984E), mRNA. /FEA=mRNA /GEN=DXS6984E /PROD=p75NTR-associated cell death executor; ovariangranulosa cell protein (13kD) /DB_XREF=gi:7657043 /UG=Hs.17775 p75NTR-associated cell death executor; ovarian granulosa cell protein (13kD) /FL=gb:NM_014380.1 gb:AF187064.1 NM_014380 nerve growth factor receptor (TNFRSF16) associated protein 1 NGFRAP1 27018 NM_001282674 /// NM_014380 /// NM_206915 /// NM_206917 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005123 // death receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 217964_at NM_017775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017775.1 /DEF=Homo sapiens hypothetical protein FLJ20343 (FLJ20343), mRNA. /FEA=mRNA /GEN=FLJ20343 /PROD=hypothetical protein FLJ20343 /DB_XREF=gi:8923319 /UG=Hs.252692 hypothetical protein FLJ20343 /FL=gb:NM_017775.1 NM_017775 tetratricopeptide repeat domain 19 TTC19 54902 NM_001271420 /// NM_017775 0000910 // cytokinesis // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0034551 // mitochondrial respiratory chain complex III assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // traceable author statement 0005515 // protein binding // inferred from physical interaction 217965_s_at NM_013260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013260.1 /DEF=Homo sapiens transcriptional regulator protein (HCNGP), mRNA. /FEA=mRNA /GEN=HCNGP /PROD=transcriptional regulator protein /DB_XREF=gi:9994178 /UG=Hs.27299 transcriptional regulator protein /FL=gb:AF119664.1 gb:NM_013260.1 NM_013260 SAP30 binding protein SAP30BP 29115 NM_013260 /// XM_005257256 /// XM_006721849 /// XR_243648 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217966_s_at NM_022083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022083.1 /DEF=Homo sapiens niban protein (NIBAN), mRNA. /FEA=mRNA /GEN=NIBAN /PROD=niban protein /DB_XREF=gi:11545796 /UG=Hs.48778 niban protein /FL=gb:AB050477.1 gb:NM_022083.1 gb:AF288391.1 NM_022083 family with sequence similarity 129, member A FAM129A 116496 NM_052966 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217967_s_at AF288391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288391.1 /DEF=Homo sapiens C1orf24 mRNA, complete cds. /FEA=mRNA /PROD=C1orf24 /DB_XREF=gi:12620191 /UG=Hs.48778 niban protein /FL=gb:AB050477.1 gb:NM_022083.1 gb:AF288391.1 AF288391 family with sequence similarity 129, member A FAM129A 116496 NM_052966 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 217968_at NM_003310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003310.1 /DEF=Homo sapiens tumor suppressing subtransferable candidate 1 (TSSC1), mRNA. /FEA=mRNA /GEN=TSSC1 /PROD=tumor suppressing subtransferable candidate 1 /DB_XREF=gi:4507702 /UG=Hs.4992 tumor suppressing subtransferable candidate 1 /FL=gb:BC002485.1 gb:AF019952.1 gb:NM_003310.1 NM_003310 tumor suppressing subtransferable candidate 1 TSSC1 7260 NM_003310 /// XM_006711893 0005515 // protein binding // inferred from electronic annotation 217969_at NM_013265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013265.2 /DEF=Homo sapiens chromosome 11 open reading frame2 (C11ORF2), mRNA. /FEA=mRNA /GEN=C11ORF2 /PROD=chromosome 11 open reading frame2 /DB_XREF=gi:8393008 /UG=Hs.5258 chromosome 11 open reading frame2 /FL=gb:AF024631.2 gb:NM_013265.2 NM_013265 vacuolar protein sorting 51 homolog (S. cerevisiae) VPS51 738 NM_013265 /// NR_073519 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000145 // exocyst // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000938 // GARP complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0017119 // Golgi transport complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 217970_s_at NM_015455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015455.1 /DEF=Homo sapiens KIAA1194 protein (KIAA1194), mRNA. /FEA=mRNA /GEN=KIAA1194 /PROD=DKFZP564G1964 protein /DB_XREF=gi:7661613 /UG=Hs.5801 KIAA1194 protein /FL=gb:NM_015455.1 NM_015455 CCR4-NOT transcription complex, subunit 6 CNOT6 57472 NM_015455 /// XM_005265953 /// XM_006714899 /// XM_006714900 /// XR_427808 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement /// 2000327 // positive regulation of ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217971_at NM_021970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021970.1 /DEF=Homo sapiens MEK partner 1 (MP1), mRNA. /FEA=mRNA /GEN=MP1 /PROD=MEK partner 1 /DB_XREF=gi:11496276 /UG=Hs.6361 MEK partner 1 /FL=gb:AF130115.1 gb:NM_021970.1 gb:AF201947.1 NM_021970 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 LAMTOR3 8649 NM_001243736 /// NM_021970 /// NR_024170 0016310 // phosphorylation // inferred from electronic annotation /// 0032006 // regulation of TOR signaling // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay 217972_at NM_017812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017812.1 /DEF=Homo sapiens hypothetical protein FLJ20420 (FLJ20420), mRNA. /FEA=mRNA /GEN=FLJ20420 /PROD=hypothetical protein FLJ20420 /DB_XREF=gi:8923389 /UG=Hs.6693 hypothetical protein FLJ20420 /FL=gb:NM_017812.1 NM_017812 coiled-coil-helix-coiled-coil-helix domain containing 3 CHCHD3 54927 NM_017812 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007007 // inner mitochondrial membrane organization // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from sequence or structural similarity 217973_at NM_016286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016286.1 /DEF=Homo sapiens carbonyl reductase (LOC51181), mRNA. /FEA=mRNA /GEN=LOC51181 /PROD=carbonyl reductase /DB_XREF=gi:7705924 /UG=Hs.9857 carbonyl reductase /FL=gb:BC001470.1 gb:AF113123.1 gb:NM_016286.1 NM_016286 dicarbonyl/L-xylulose reductase DCXR 51181 NM_001195218 /// NM_016286 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005997 // xylulose metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from direct assay /// 0006739 // NADP metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042732 // D-xylose metabolic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0050038 // L-xylulose reductase (NADP+) activity // inferred from direct assay 217974_at NM_016551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016551.1 /DEF=Homo sapiens seven transmembrane protein TM7SF3 (TM7SF3), mRNA. /FEA=mRNA /GEN=TM7SF3 /PROD=seven transmembrane protein TM7SF3 /DB_XREF=gi:7706574 /UG=Hs.10071 seven transmembrane protein TM7SF3 /FL=gb:BC005176.1 gb:AB032470.1 gb:NM_016551.1 NM_016551 transmembrane 7 superfamily member 3 TM7SF3 51768 NM_016551 /// XM_005253391 /// XR_242895 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 217975_at NM_016303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016303.1 /DEF=Homo sapiens pp21 homolog (LOC51186), mRNA. /FEA=mRNA /GEN=LOC51186 /PROD=pp21 homolog /DB_XREF=gi:10047099 /UG=Hs.15984 pp21 homolog /FL=gb:NM_016303.1 gb:AF125535.1 NM_016303 WW domain binding protein 5 WBP5 51186 NM_001006612 /// NM_001006613 /// NM_001006614 /// NM_016303 0050699 // WW domain binding // inferred from electronic annotation 217976_s_at NM_016141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016141.1 /DEF=Homo sapiens dynein light chain-A (LOC51143), mRNA. /FEA=mRNA /GEN=LOC51143 /PROD=dynein light chain-A /DB_XREF=gi:7705852 /UG=Hs.266483 dynein light chain-A /FL=gb:AF078849.1 gb:NM_016141.1 NM_016141 dynein, cytoplasmic 1, light intermediate chain 1 DYNC1LI1 51143 NM_016141 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 217977_at NM_016332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016332.1 /DEF=Homo sapiens selenoprotein X, 1 (SEPX1), mRNA. /FEA=mRNA /GEN=SEPX1 /PROD=selenoprotein X, 1 /DB_XREF=gi:7706510 /UG=Hs.279623 selenoprotein X, 1 /FL=gb:AF187272.1 gb:BC003127.1 gb:AF166124.1 gb:NM_016332.1 NM_016332 methionine sulfoxide reductase B1 MSRB1 51734 NM_016332 0002376 // immune system process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030091 // protein repair // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity 0003779 // actin binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0033743 // peptide-methionine (R)-S-oxide reductase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070191 // methionine-R-sulfoxide reductase activity // inferred from electronic annotation 217978_s_at NM_017582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017582.1 /DEF=Homo sapiens NICE-5 protein (HSA243666), mRNA. /FEA=mRNA /GEN=HSA243666 /PROD=NICE-5 protein /DB_XREF=gi:8923743 /UG=Hs.284233 NICE-5 protein /FL=gb:AF116721.1 gb:NM_017582.1 NM_017582 ubiquitin-conjugating enzyme E2Q family member 1 UBE2Q1 55585 NM_017582 /// XM_005245315 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 217979_at NM_014399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014399.1 /DEF=Homo sapiens tetraspan NET-6 protein (NET-6), mRNA. /FEA=mRNA /GEN=NET-6 /PROD=tetraspan NET-6 protein /DB_XREF=gi:7657372 /UG=Hs.284243 tetraspan NET-6 protein /FL=gb:AF120265.1 gb:AF100759.1 gb:NM_014399.1 NM_014399 tetraspanin 13 TSPAN13 27075 NM_014399 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 217980_s_at NM_017840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017840.1 /DEF=Homo sapiens hypothetical protein FLJ20484 (FLJ20484), mRNA. /FEA=mRNA /GEN=FLJ20484 /PROD=hypothetical protein FLJ20484 /DB_XREF=gi:8923447 /UG=Hs.5080 hypothetical protein FLJ20484 /FL=gb:AF275806.1 gb:BC001040.1 gb:NM_017840.1 gb:AF183428.1 NM_017840 mitochondrial ribosomal protein L16 MRPL16 54948 NM_017840 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 217981_s_at NM_012192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012192.1 /DEF=Homo sapiens fracture callus 1 (rat) homolog (FXC1), mRNA. /FEA=mRNA /GEN=FXC1 /PROD=fracture callus 1 (rat) homolog /DB_XREF=gi:6912381 /UG=Hs.54943 fracture callus 1 (rat) homolog /FL=gb:AF150105.1 gb:AF152355.1 gb:NM_012192.1 gb:AF183415.1 NM_012192 translocase of inner mitochondrial membrane 10 homolog B (yeast) TIMM10B 26515 NM_012192 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042719 // mitochondrial intermembrane space protein transporter complex // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 217982_s_at NM_006791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006791.1 /DEF=Homo sapiens MORF-related gene 15 (MRG15), mRNA. /FEA=mRNA /GEN=MRG15 /PROD=MORF-related gene 15 /DB_XREF=gi:5803101 /UG=Hs.6353 MORF-related gene 15 /FL=gb:BC002936.1 gb:AF070664.1 gb:AF100615.1 gb:NM_006791.1 gb:AF161546.1 gb:AF167173.1 NM_006791 mortality factor 4 like 1 MORF4L1 10933 NM_001265603 /// NM_001265604 /// NM_001265605 /// NM_006791 /// NM_206839 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 217983_s_at NM_003730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003730.2 /DEF=Homo sapiens ribonuclease 6 precursor (RNASE6PL), mRNA. /FEA=mRNA /GEN=RNASE6PL /PROD=ribonuclease 6 precursor /DB_XREF=gi:5231227 /UG=Hs.8297 ribonuclease 6 precursor /FL=gb:BC001660.1 gb:BC001819.1 gb:U85625.2 gb:NM_003730.2 NM_003730 ribonuclease T2 RNASET2 8635 NM_003730 /// XM_005267186 /// XM_005267187 0006401 // RNA catabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033897 // ribonuclease T2 activity // inferred from electronic annotation 217984_at NM_003730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003730.2 /DEF=Homo sapiens ribonuclease 6 precursor (RNASE6PL), mRNA. /FEA=mRNA /GEN=RNASE6PL /PROD=ribonuclease 6 precursor /DB_XREF=gi:5231227 /UG=Hs.8297 ribonuclease 6 precursor /FL=gb:BC001660.1 gb:BC001819.1 gb:U85625.2 gb:NM_003730.2 NM_003730 ribonuclease T2 RNASET2 8635 NM_003730 /// XM_005267186 /// XM_005267187 0006401 // RNA catabolic process // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033897 // ribonuclease T2 activity // inferred from electronic annotation 217985_s_at AA102574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA102574 /FEA=EST /DB_XREF=gi:1647766 /DB_XREF=est:zn42c01.s1 /CLONE=IMAGE:550080 /UG=Hs.8858 bromodomain adjacent to zinc finger domain, 1A /FL=gb:AB032252.1 gb:NM_013448.1 AA102574 bromodomain adjacent to zinc finger domain, 1A BAZ1A 11177 NM_013448 /// NM_182648 0006261 // DNA-dependent DNA replication // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0000228 // nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0008623 // CHRAC // inferred from direct assay /// 0016590 // ACF complex // traceable author statement 0004402 // histone acetyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217986_s_at NM_013448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013448.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 1A (BAZ1A), mRNA. /FEA=mRNA /GEN=BAZ1A /PROD=bromodomain adjacent to zinc finger domain, 1A /DB_XREF=gi:7304918 /UG=Hs.8858 bromodomain adjacent to zinc finger domain, 1A /FL=gb:AB032252.1 gb:NM_013448.1 NM_013448 bromodomain adjacent to zinc finger domain, 1A BAZ1A 11177 NM_013448 /// NM_182648 0006261 // DNA-dependent DNA replication // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement 0000228 // nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0008623 // CHRAC // inferred from direct assay /// 0016590 // ACF complex // traceable author statement 0004402 // histone acetyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217987_at NM_019048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019048.1 /DEF=Homo sapiens hypothetical protein (FLJ20752), mRNA. /FEA=mRNA /GEN=FLJ20752 /PROD=hypothetical protein /DB_XREF=gi:9506696 /UG=Hs.101364 hypothetical protein /FL=gb:BC001243.1 gb:NM_019048.1 NM_019048 asparagine synthetase domain containing 1 ASNSD1 54529 NM_019048 /// XM_005246653 0006529 // asparagine biosynthetic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation 0004066 // asparagine synthase (glutamine-hydrolyzing) activity // inferred from electronic annotation 217988_at NM_021178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021178.1 /DEF=Homo sapiens enhancer of invasion 10 (HEI10), mRNA. /FEA=mRNA /GEN=HEI10 /PROD=enhancer of invasion 10 /DB_XREF=gi:10863978 /UG=Hs.107003 enhancer of invasion 10 /FL=gb:NM_021178.1 gb:BC000369.1 gb:BC001218.1 gb:BC004435.1 gb:AF216381.1 NM_021178 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase CCNB1IP1 57820 NM_021178 /// NM_182849 /// NM_182851 /// NM_182852 0001825 // blastocyst formation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from sequence or structural similarity /// 0007286 // spermatid development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0051026 // chiasma assembly // inferred from sequence or structural similarity 0000795 // synaptonemal complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217989_at NM_016245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016245.1 /DEF=Homo sapiens retinal short-chain dehydrogenasereductase retSDR2 (LOC51170), mRNA. /FEA=mRNA /GEN=LOC51170 /PROD=retinal short-chain dehydrogenasereductaseretSDR2 /DB_XREF=gi:7705904 /UG=Hs.12150 retinal short-chain dehydrogenasereductase retSDR2 /FL=gb:AF126780.1 gb:NM_016245.1 NM_016245 hydroxysteroid (17-beta) dehydrogenase 11 HSD17B11 51170 NM_016245 /// XM_006714232 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006710 // androgen catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0016229 // steroid dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 217990_at NM_016576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016576.1 /DEF=Homo sapiens GMPR2 for guanosine monophosphate reductase isolog (LOC51292), mRNA. /FEA=mRNA /GEN=LOC51292 /PROD=GMPR2 for guanosine monophosphate reductaseisolog /DB_XREF=gi:7706108 /UG=Hs.234546 GMPR2 for guanosine monophosphate reductase isolog /FL=gb:AB032903.1 gb:NM_016576.1 gb:AF135159.1 NM_016576 guanosine monophosphate reductase 2 GMPR2 51292 NM_001002000 /// NM_001002001 /// NM_001002002 /// NM_001283021 /// NM_001283022 /// NM_001283023 /// NM_016576 /// NR_104265 /// XM_005267740 /// XM_005267741 /// XM_005267742 /// XM_006720165 /// XR_429318 0006144 // purine nucleobase metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046037 // GMP metabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 1902560 // GMP reductase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003920 // GMP reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217991_x_at NM_018070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018070.1 /DEF=Homo sapiens hypothetical protein FLJ10355 (FLJ10355), mRNA. /FEA=mRNA /GEN=FLJ10355 /PROD=hypothetical protein FLJ10355 /DB_XREF=gi:8922373 /UG=Hs.266914 hypothetical protein FLJ10355 /FL=gb:BC004335.1 gb:NM_018070.1 NM_018070 single stranded DNA binding protein 3 SSBP3 23648 NM_001009955 /// NM_018070 /// NM_145716 /// XM_005270713 /// XM_006710545 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021501 // prechordal plate formation // inferred from electronic annotation /// 0021547 // midbrain-hindbrain boundary initiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation /// 0060323 // head morphogenesis // inferred from electronic annotation /// 2000744 // positive regulation of anterior head development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 217992_s_at NM_024329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024329.1 /DEF=Homo sapiens hypothetical protein MGC4342 (MGC4342), mRNA. /FEA=mRNA /GEN=MGC4342 /PROD=hypothetical protein MGC4342 /DB_XREF=gi:13443015 /UG=Hs.301342 hypothetical protein MGC4342 /FL=gb:BC003033.1 gb:NM_024329.1 NM_024329 EF-hand domain family, member D2 EFHD2 79180 NM_024329 /// XM_005246000 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 217993_s_at NM_013283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013283.1 /DEF=Homo sapiens methionine adenosyltransferase II, beta (MAT2B), mRNA. /FEA=mRNA /GEN=MAT2B /PROD=methionine adenosyltransferase II, beta /DB_XREF=gi:11034824 /UG=Hs.54642 methionine adenosyltransferase II, beta /FL=gb:NM_013283.1 gb:AF113225.1 gb:AL136664.1 gb:AF182814.1 NM_013283 methionine adenosyltransferase II, beta MAT2B 27430 NM_013283 /// NM_182796 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from direct assay /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048269 // methionine adenosyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0048270 // methionine adenosyltransferase regulator activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 217994_x_at NM_017871 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017871.1 /DEF=Homo sapiens hypothetical protein FLJ20542 (FLJ20542), mRNA. /FEA=mRNA /GEN=FLJ20542 /PROD=hypothetical protein FLJ20542 /DB_XREF=gi:8923511 /UG=Hs.6449 hypothetical protein FLJ20542 /FL=gb:AL136813.1 gb:NM_017871.1 NM_017871 cleavage and polyadenylation specific factor 3-like /// microRNA 6727 CPSF3L /// MIR6727 54973 /// 102465435 NM_001256456 /// NM_001256460 /// NM_001256462 /// NM_001256463 /// NM_017871 /// NM_032179 /// NR_106785 /// XM_005244763 /// XM_006710715 /// XR_426614 0008152 // metabolic process // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 217995_at NM_021199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021199.1 /DEF=Homo sapiens CGI-44 protein; sulfide dehydrogenase like (yeast) (CGI-44), mRNA. /FEA=mRNA /GEN=CGI-44 /PROD=CGI-44 protein; sulfide dehydrogenase like(yeast) /DB_XREF=gi:10864010 /UG=Hs.8185 CGI-44 protein; sulfide dehydrogenase like (yeast) /FL=gb:NM_021199.1 gb:AF151802.1 gb:AF118085.1 NM_021199 sulfide quinone reductase-like (yeast) SQRDL 58472 NM_001271213 /// NM_021199 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0070224 // sulfide:quinone oxidoreductase activity // traceable author statement 217996_at AA576961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA576961 /FEA=EST /DB_XREF=gi:2354435 /DB_XREF=est:nm82d08.s1 /CLONE=IMAGE:1074735 /UG=Hs.82101 pleckstrin homology-like domain, family A, member 1 /FL=gb:NM_007350.1 AA576961 pleckstrin homology-like domain, family A, member 1 PHLDA1 22822 NM_007350 0006915 // apoptotic process // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045210 // FasL biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 217997_at AI795908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI795908 /FEA=EST /DB_XREF=gi:5361371 /DB_XREF=est:wh40a05.x1 /CLONE=IMAGE:2383184 /UG=Hs.82101 pleckstrin homology-like domain, family A, member 1 /FL=gb:NM_007350.1 AI795908 pleckstrin homology-like domain, family A, member 1 PHLDA1 22822 NM_007350 0006915 // apoptotic process // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045210 // FasL biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 217998_at NM_007350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007350.1 /DEF=Homo sapiens pleckstrin homology-like domain, family A, member 1 (PHLDA1), mRNA. /FEA=mRNA /GEN=PHLDA1 /PROD=pleckstrin homology-like domain, family A,member 1 /DB_XREF=gi:6679302 /UG=Hs.82101 pleckstrin homology-like domain, family A, member 1 /FL=gb:NM_007350.1 NM_007350 pleckstrin homology-like domain, family A, member 1 PHLDA1 22822 NM_007350 0006915 // apoptotic process // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045210 // FasL biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 217999_s_at NM_007350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007350.1 /DEF=Homo sapiens pleckstrin homology-like domain, family A, member 1 (PHLDA1), mRNA. /FEA=mRNA /GEN=PHLDA1 /PROD=pleckstrin homology-like domain, family A,member 1 /DB_XREF=gi:6679302 /UG=Hs.82101 pleckstrin homology-like domain, family A, member 1 /FL=gb:NM_007350.1 NM_007350 pleckstrin homology-like domain, family A, member 1 PHLDA1 22822 NM_007350 0006915 // apoptotic process // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045210 // FasL biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 218000_s_at NM_007350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007350.1 /DEF=Homo sapiens pleckstrin homology-like domain, family A, member 1 (PHLDA1), mRNA. /FEA=mRNA /GEN=PHLDA1 /PROD=pleckstrin homology-like domain, family A,member 1 /DB_XREF=gi:6679302 /UG=Hs.82101 pleckstrin homology-like domain, family A, member 1 /FL=gb:NM_007350.1 NM_007350 pleckstrin homology-like domain, family A, member 1 PHLDA1 22822 NM_007350 0006915 // apoptotic process // inferred from electronic annotation /// 0021879 // forebrain neuron differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045210 // FasL biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 218001_at NM_016034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016034.1 /DEF=Homo sapiens CGI-91 protein (LOC51116), mRNA. /FEA=mRNA /GEN=LOC51116 /PROD=CGI-91 protein /DB_XREF=gi:7705804 /UG=Hs.20776 CGI-91 protein /FL=gb:AF151849.1 gb:NM_016034.1 NM_016034 mitochondrial ribosomal protein S2 MRPS2 51116 NM_016034 /// NR_051967 /// NR_051968 /// NR_051969 /// NR_051970 /// XM_006717136 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 218002_s_at NM_004887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004887.1 /DEF=Homo sapiens small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK) (SCYB14), mRNA. /FEA=mRNA /GEN=SCYB14 /PROD=small inducible cytokine subfamily B(Cys-X-Cys), member 14 (BRAK) /DB_XREF=gi:4757869 /UG=Hs.24395 small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK) /FL=gb:BC003513.1 gb:AF073957.1 gb:NM_004887.1 gb:AF144103.1 gb:AF106911.1 NM_004887 chemokine (C-X-C motif) ligand 14 CXCL14 9547 NM_004887 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0048839 // inner ear development // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation 218003_s_at NM_002013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002013.1 /DEF=Homo sapiens FK506-binding protein 3 (25kD) (FKBP3), mRNA. /FEA=mRNA /GEN=FKBP3 /PROD=FK506-binding protein 3 (25kD) /DB_XREF=gi:4503726 /UG=Hs.306024 FK506-binding protein 3 (25kD) /FL=gb:M96256.1 gb:M90820.1 gb:M90309.1 gb:NM_002013.1 NM_002013 FK506 binding protein 3, 25kDa FKBP3 2287 NM_002013 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218004_at NM_018045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018045.1 /DEF=Homo sapiens hypothetical protein FLJ10276 (FLJ10276), mRNA. /FEA=mRNA /GEN=FLJ10276 /PROD=hypothetical protein FLJ10276 /DB_XREF=gi:8922323 /UG=Hs.6937 hypothetical protein FLJ10276 /FL=gb:NM_018045.1 NM_018045 BSD domain containing 1 BSDC1 55108 NM_001143888 /// NM_001143889 /// NM_001143890 /// NM_018045 /// XM_005270985 /// XM_005270986 218005_at AA744771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA744771 /FEA=EST /DB_XREF=gi:2783535 /DB_XREF=est:ny71d07.s1 /CLONE=IMAGE:1283725 /UG=Hs.108642 zinc finger protein 22 (KOX 15) /FL=gb:NM_006963.1 AA744771 zinc finger protein 22 ZNF22 7570 NM_006963 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0042476 // odontogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218006_s_at NM_006963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006963.1 /DEF=Homo sapiens zinc finger protein 22 (KOX 15) (ZNF22), mRNA. /FEA=mRNA /GEN=ZNF22 /PROD=zinc finger protein 22 (KOX 15) /DB_XREF=gi:5902159 /UG=Hs.108642 zinc finger protein 22 (KOX 15) /FL=gb:NM_006963.1 NM_006963 zinc finger protein 22 ZNF22 7570 NM_006963 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0042476 // odontogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218007_s_at NM_015920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015920.1 /DEF=Homo sapiens 40S ribosomal protein S27 isoform (LOC51065), mRNA. /FEA=mRNA /GEN=LOC51065 /PROD=40S ribosomal protein S27 isoform /DB_XREF=gi:7705705 /UG=Hs.108957 40S ribosomal protein S27 isoform /FL=gb:BC003667.1 gb:AF070668.1 gb:NM_015920.1 NM_015920 ribosomal protein S27-like RPS27L 51065 NM_015920 0006281 // DNA repair // inferred from mutant phenotype /// 0006412 // translation // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008494 // translation activator activity // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218008_at NM_017994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017994.1 /DEF=Homo sapiens hypothetical protein FLJ10099 (FLJ10099), mRNA. /FEA=mRNA /GEN=FLJ10099 /PROD=hypothetical protein FLJ10099 /DB_XREF=gi:8922228 /UG=Hs.278619 hypothetical protein FLJ10099 /FL=gb:NM_017994.1 NM_017994 transmembrane protein 248 TMEM248 55069 NM_017994 /// XM_005250482 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218009_s_at NM_003981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003981.1 /DEF=Homo sapiens protein regulator of cytokinesis 1 (PRC1), mRNA. /FEA=mRNA /GEN=PRC1 /PROD=protein regulator of cytokinesis 1 /DB_XREF=gi:4506038 /UG=Hs.5101 protein regulator of cytokinesis 1 /FL=gb:BC003138.1 gb:AF044588.1 gb:NM_003981.1 NM_003981 protein regulator of cytokinesis 1 PRC1 9055 NM_001267580 /// NM_003981 /// NM_199413 /// NM_199414 /// XM_005254986 /// XM_005254987 /// XM_006720759 /// XM_006720760 0000022 // mitotic spindle elongation // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218010_x_at NM_024299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024299.1 /DEF=Homo sapiens hypothetical protein MGC2479 (MGC2479), mRNA. /FEA=mRNA /GEN=MGC2479 /PROD=hypothetical protein MGC2479 /DB_XREF=gi:13236523 /UG=Hs.79625 hypothetical protein MGC2479 /FL=gb:BC002531.1 gb:NM_024299.1 NM_024299 pancreatic progenitor cell differentiation and proliferation factor PPDPF 79144 NM_024299 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 218011_at NM_024292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024292.1 /DEF=Homo sapiens ubiquitin-like 5 (UBL5), mRNA. /FEA=mRNA /GEN=UBL5 /PROD=ubiquitin-like 5 /DB_XREF=gi:13236509 /UG=Hs.109701 ubiquitin-like 5 /FL=gb:AF313915.1 gb:NM_024292.1 NM_024292 ubiquitin-like 5 UBL5 59286 NM_001048241 /// NM_024292 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218012_at NM_022117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022117.1 /DEF=Homo sapiens cutaneous T-cell lymphoma-associated tumor antigen se20-4 (SE20-4), mRNA. /FEA=mRNA /GEN=SE20-4 /PROD=cutaneous T-cell lymphoma-associated tumorantigen se20-4 /DB_XREF=gi:11545834 /UG=Hs.136164 cutaneous T-cell lymphoma-associated tumor antigen se20-4 /FL=gb:AF273046.1 gb:NM_022117.1 gb:AF254794.1 NM_022117 TSPY-like 2 TSPYL2 64061 NM_022117 /// XM_006724592 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000182 // rDNA binding // non-traceable author statement 218013_x_at NM_016221 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016221.1 /DEF=Homo sapiens dynactin p62 subunit (LOC51164), mRNA. /FEA=mRNA /GEN=LOC51164 /PROD=dynactin p62 subunit /DB_XREF=gi:7705892 /UG=Hs.180952 dynactin 4 (p62) /FL=gb:AF195120.1 gb:NM_016221.1 NM_016221 dynactin 4 (p62) DCTN4 51164 NM_001135643 /// NM_001135644 /// NM_016221 /// XM_005268457 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation 0047485 // protein N-terminus binding // inferred from physical interaction 218014_at NM_024844 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024844.1 /DEF=Homo sapiens hypothetical protein FLJ12549 (FLJ12549), mRNA. /FEA=mRNA /GEN=FLJ12549 /PROD=hypothetical protein FLJ12549 /DB_XREF=gi:13376258 /UG=Hs.184352 hypothetical protein FLJ12549 /FL=gb:BC000697.1 gb:NM_024844.1 NM_024844 nucleoporin 85kDa NUP85 79902 NM_024844 /// XM_005257690 /// XM_005257692 /// XM_005257693 /// XM_006722094 /// XR_243683 /// XR_429921 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218015_s_at NM_020135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020135.1 /DEF=Homo sapiens putative helicase RUVBL (LOC56897), mRNA. /FEA=mRNA /GEN=LOC56897 /PROD=putative helicase RUVBL /DB_XREF=gi:9910349 /UG=Hs.236828 putative helicase RUVBL /FL=gb:AF218313.1 gb:NM_020135.1 NM_020135 Werner helicase interacting protein 1 WRNIP1 56897 NM_020135 /// NM_130395 /// XM_005249232 /// XM_005249234 0000731 // DNA synthesis involved in DNA repair // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218016_s_at NM_018119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018119.1 /DEF=Homo sapiens hypothetical protein FLJ10509 (FLJ10509), mRNA. /FEA=mRNA /GEN=FLJ10509 /PROD=hypothetical protein FLJ10509 /DB_XREF=gi:8922476 /UG=Hs.274319 hypothetical protein FLJ10509 /FL=gb:BC000285.1 gb:NM_018119.1 NM_018119 DNA-directed RNA polymerase III subunit RPC5-like /// polymerase (RNA) III (DNA directed) polypeptide E (80kD) LOC101060521 /// POLR3E 55718 /// 101060521 NM_001258033 /// NM_001258034 /// NM_001258035 /// NM_001258036 /// NM_018119 /// NR_047581 /// XM_005276498 /// XM_006721063 /// XM_006726613 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation 218017_s_at NM_025070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025070.1 /DEF=Homo sapiens hypothetical protein FLJ22242 (FLJ22242), mRNA. /FEA=mRNA /GEN=FLJ22242 /PROD=hypothetical protein FLJ22242 /DB_XREF=gi:13376612 /UG=Hs.288057 hypothetical protein FLJ22242 /FL=gb:NM_025070.1 NM_025070 heparan-alpha-glucosaminide N-acetyltransferase HGSNAT 138050 NM_152419 /// XM_005273409 /// XM_005273410 /// XM_005273411 /// XM_005273412 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007041 // lysosomal transport // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015019 // heparan-alpha-glucosaminide N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from direct assay 218018_at AW449022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW449022 /FEA=EST /DB_XREF=gi:6989798 /DB_XREF=est:UI-H-BI3-ake-f-11-0-UI.s1 /CLONE=IMAGE:2734220 /UG=Hs.4746 hypothetical protein FLJ21324 /FL=gb:NM_021941.1 gb:BC003651.1 AW449022 pyridoxal (pyridoxine, vitamin B6) kinase PDXK 8566 NM_003681 /// NM_021941 /// XM_005261195 /// XM_005261196 /// XM_005261198 /// XM_005261199 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0009443 // pyridoxal 5'-phosphate salvage // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042816 // vitamin B6 metabolic process // inferred by curator /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0042823 // pyridoxal phosphate biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008478 // pyridoxal kinase activity // inferred from direct assay /// 0008478 // pyridoxal kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from direct assay /// 0031402 // sodium ion binding // inferred from direct assay /// 0031403 // lithium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218019_s_at NM_021941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021941.1 /DEF=Homo sapiens hypothetical protein FLJ21324 (FLJ21324), mRNA. /FEA=mRNA /GEN=FLJ21324 /PROD=hypothetical protein FLJ21324 /DB_XREF=gi:11345479 /UG=Hs.4746 hypothetical protein FLJ21324 /FL=gb:NM_021941.1 gb:BC003651.1 NM_021941 pyridoxal (pyridoxine, vitamin B6) kinase PDXK 8566 NM_003681 /// NM_021941 /// XM_005261195 /// XM_005261196 /// XM_005261198 /// XM_005261199 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0009443 // pyridoxal 5'-phosphate salvage // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042816 // vitamin B6 metabolic process // inferred by curator /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0042823 // pyridoxal phosphate biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008478 // pyridoxal kinase activity // inferred from direct assay /// 0008478 // pyridoxal kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from direct assay /// 0031402 // sodium ion binding // inferred from direct assay /// 0031403 // lithium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218020_s_at NM_021943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021943.1 /DEF=Homo sapiens hypothetical protein FLJ13222 (FLJ13222), mRNA. /FEA=mRNA /GEN=FLJ13222 /PROD=hypothetical protein FLJ13222 /DB_XREF=gi:11345483 /UG=Hs.6120 hypothetical protein FLJ13222 /FL=gb:NM_021943.1 NM_021943 zinc finger, AN1-type domain 3 ZFAND3 60685 NM_021943 /// XM_005249269 /// XM_006715155 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218021_at NM_021004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021004.1 /DEF=Homo sapiens peroxisomal short-chain alcohol dehydrogenase (SCAD-SRL), mRNA. /FEA=mRNA /GEN=SCAD-SRL /PROD=peroxisomal short-chain alcohol dehydrogenase /DB_XREF=gi:10337604 /UG=Hs.6318 peroxisomal short-chain alcohol dehydrogenase /FL=gb:NM_021004.1 gb:AB045131.1 gb:BC003019.1 gb:AF044127.1 NM_021004 dehydrogenase/reductase (SDR family) member 4 /// dehydrogenase/reductase (SDR family) member 4 like 2 DHRS4 /// DHRS4L2 10901 /// 317749 NM_001193635 /// NM_001193636 /// NM_001193637 /// NM_001282987 /// NM_001282988 /// NM_001282989 /// NM_001282990 /// NM_001282991 /// NM_021004 /// NM_198083 /// XM_006720005 /// XM_006720006 0006066 // alcohol metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from direct assay /// 0042180 // cellular ketone metabolic process // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000253 // 3-keto sterol reductase activity // inferred from direct assay /// 0004090 // carbonyl reductase (NADPH) activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018455 // alcohol dehydrogenase [NAD(P)+] activity // inferred from direct assay 218022_at NM_016440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016440.1 /DEF=Homo sapiens VRK3 for vaccinia related kinase 3 (LOC51231), mRNA. /FEA=mRNA /GEN=LOC51231 /PROD=VRK3 for vaccinia related kinase 3 /DB_XREF=gi:7705992 /UG=Hs.98289 VRK3 for vaccinia related kinase 3 /FL=gb:AB031052.1 gb:NM_016440.1 NM_016440 vaccinia related kinase 3 VRK3 51231 NM_001025778 /// NM_016440 /// XM_005258971 /// XM_005258972 /// XM_005258974 /// XM_006723237 /// XM_006723238 /// XR_243939 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation 218023_s_at NM_016605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016605.1 /DEF=Homo sapiens putative nuclear protein (LOC51307), mRNA. /FEA=mRNA /GEN=LOC51307 /PROD=putative nuclear protein /DB_XREF=gi:7706138 /UG=Hs.102469 putative nuclear protein /FL=gb:AF251040.1 gb:NM_016605.1 NM_016605 family with sequence similarity 53, member C FAM53C 51307 NM_001135647 /// NM_016605 218024_at NM_016098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016098.1 /DEF=Homo sapiens HSPC040 protein (LOC51660), mRNA. /FEA=mRNA /GEN=LOC51660 /PROD=HSPC040 protein /DB_XREF=gi:7706368 /UG=Hs.108725 HSPC040 protein /FL=gb:AF275811.1 gb:BC000810.1 gb:AF151887.1 gb:AF125101.1 gb:NM_016098.1 NM_016098 mitochondrial pyruvate carrier 1 MPC1 51660 NM_001270879 /// NM_016098 /// NR_073093 /// XM_006715499 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006850 // mitochondrial pyruvate transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901475 // pyruvate transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0050833 // pyruvate transmembrane transporter activity // inferred from electronic annotation 218025_s_at NM_006117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006117.1 /DEF=Homo sapiens peroxisomal D3,D2-enoyl-CoA isomerase (PECI), mRNA. /FEA=mRNA /GEN=PECI /PROD=peroxisomal D3,D2-enoyl-CoA isomerase /DB_XREF=gi:5174624 /UG=Hs.15250 peroxisomal D3,D2-enoyl-CoA isomerase /FL=gb:AL136642.1 gb:BC002668.1 gb:AF069301.1 gb:AF153612.1 gb:NM_006117.1 gb:AF244138.1 NM_006117 enoyl-CoA delta isomerase 2 ECI2 10455 NM_001166010 /// NM_006117 /// NM_206836 /// NR_028588 /// XM_006714957 0008152 // metabolic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004165 // dodecenoyl-CoA delta-isomerase activity // inferred from direct assay /// 0004165 // dodecenoyl-CoA delta-isomerase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 218026_at NM_014019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014019.1 /DEF=Homo sapiens HSPC009 protein (HSPC009), mRNA. /FEA=mRNA /GEN=HSPC009 /PROD=HSPC009 protein /DB_XREF=gi:7661731 /UG=Hs.16059 HSPC009 protein /FL=gb:BC002698.1 gb:AF070665.1 gb:NM_014019.1 NM_014019 cytochrome c oxidase assembly factor 3 COA3 28958 NM_001040431 0033617 // mitochondrial respiratory chain complex IV assembly // inferred from mutant phenotype /// 0070131 // positive regulation of mitochondrial translation // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218027_at NM_014175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014175.1 /DEF=Homo sapiens HSPC145 protein (HSPC145), mRNA. /FEA=mRNA /GEN=HSPC145 /PROD=HSPC145 protein /DB_XREF=gi:7661805 /UG=Hs.18349 HSPC145 protein /FL=gb:AL136665.1 gb:BC000891.1 gb:AF161494.1 gb:NM_014175.1 NM_014175 mitochondrial ribosomal protein L15 MRPL15 29088 NM_014175 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218028_at NM_016031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016031.1 /DEF=Homo sapiens elongation of very long chain fatty acids (FEN1Elo2, SUR4Elo3, yeast)-like 1 (ELOVL1), mRNA. /FEA=mRNA /GEN=ELOVL1 /PROD=elongation of very long chain fatty acids(FEN1Elo2, SUR4Elo3, yeast)-like 1 /DB_XREF=gi:7705798 /UG=Hs.25597 elongation of very long chain fatty acids (FEN1Elo2, SUR4Elo3, yeast)-like 1 /FL=gb:BC000618.1 gb:NM_022821.1 gb:AF151846.1 gb:NM_016031.1 NM_016031 ELOVL fatty acid elongase 1 /// microRNA 6734 ELOVL1 /// MIR6734 64834 /// 102466723 NM_001256399 /// NM_001256401 /// NM_001256402 /// NM_022821 /// NR_046117 /// NR_106792 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // inferred from mutant phenotype /// 0034625 // fatty acid elongation, monounsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 218029_at NM_024519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024519.1 /DEF=Homo sapiens hypothetical protein FLJ13725 (FLJ13725), mRNA. /FEA=mRNA /GEN=FLJ13725 /PROD=hypothetical protein FLJ13725 /DB_XREF=gi:13375657 /UG=Hs.3074 hypothetical protein FLJ13725 /FL=gb:NM_024519.1 NM_024519 family with sequence similarity 65, member A FAM65A 79567 NM_001193522 /// NM_001193523 /// NM_001193524 /// NM_024519 /// XM_006721269 /// XM_006721270 0007165 // signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation 218030_at NM_014030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014030.1 /DEF=Homo sapiens G protein-coupled receptor kinase-interactor 1 (GIT1), mRNA. /FEA=mRNA /GEN=GIT1 /PROD=G protein-coupled receptor kinase-interactor 1 /DB_XREF=gi:7661711 /UG=Hs.318339 G protein-coupled receptor kinase-interactor 1 /FL=gb:AF124490.1 gb:NM_014030.1 NM_014030 G protein-coupled receptor kinase interacting ArfGAP 1 GIT1 28964 NM_001085454 /// NM_014030 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218031_s_at NM_018589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018589.1 /DEF=Homo sapiens hypothetical protein PRO1635 (PRO1635), mRNA. /FEA=mRNA /GEN=PRO1635 /PROD=hypothetical protein PRO1635 /DB_XREF=gi:8924068 /UG=Hs.60548 hypothetical protein PRO1635 /FL=gb:AF116643.1 gb:NM_018589.1 NM_018589 forkhead box N3 FOXN3 1112 NM_001085471 /// NM_005197 0000077 // DNA damage checkpoint // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218032_at AF070673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF070673.1 /DEF=Homo sapiens stannin mRNA, complete cds. /FEA=mRNA /PROD=stannin /DB_XREF=gi:3978241 /UG=Hs.76691 stannin /FL=gb:AF030196.1 gb:AF070673.1 gb:NM_003498.1 gb:AL161976.1 AF070673 stannin SNN 8303 NM_003498 0006950 // response to stress // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218033_s_at NM_003498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003498.1 /DEF=Homo sapiens stannin (SNN), mRNA. /FEA=mRNA /GEN=SNN /PROD=Stannin /DB_XREF=gi:4507116 /UG=Hs.76691 stannin /FL=gb:AF030196.1 gb:AF070673.1 gb:NM_003498.1 gb:AL161976.1 NM_003498 stannin SNN 8303 NM_003498 0006950 // response to stress // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218034_at NM_016068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016068.1 /DEF=Homo sapiens CGI-135 protein (LOC51024), mRNA. /FEA=mRNA /GEN=LOC51024 /PROD=CGI-135 protein /DB_XREF=gi:7705631 /UG=Hs.84344 CGI-135 protein /FL=gb:BC003540.1 gb:AF151893.1 gb:NM_016068.1 NM_016068 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) FIS1 51024 NM_016068 0000266 // mitochondrial fission // inferred from direct assay /// 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0000422 // mitochondrion degradation // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0010821 // regulation of mitochondrion organization // inferred from mutant phenotype /// 0016559 // peroxisome fission // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031307 // integral component of mitochondrial outer membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 218035_s_at NM_019027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019027.1 /DEF=Homo sapiens hypothetical protein (FLJ20273), mRNA. /FEA=mRNA /GEN=FLJ20273 /PROD=hypothetical protein /DB_XREF=gi:9506670 /UG=Hs.95549 hypothetical protein /FL=gb:NM_019027.1 NM_019027 RNA binding motif protein 47 RBM47 54502 NM_001098634 /// NM_019027 /// XM_005248103 /// XM_005248107 /// XM_005248108 /// XM_005248109 /// XM_005248110 /// XM_005248111 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218036_x_at NM_015938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015938.1 /DEF=Homo sapiens CGI-07 protein (LOC51068), mRNA. /FEA=mRNA /GEN=LOC51068 /PROD=CGI-07 protein /DB_XREF=gi:7705711 /UG=Hs.181022 CGI-07 protein /FL=gb:AF132941.1 gb:NM_015938.1 NM_015938 NMD3 ribosome export adaptor NMD3 51068 NM_015938 /// XM_005247511 /// XM_005247512 0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0030674 // protein binding, bridging // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 218037_at NM_024293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024293.1 /DEF=Homo sapiens hypothetical protein MGC3035 (MGC3035), mRNA. /FEA=mRNA /GEN=MGC3035 /PROD=hypothetical protein MGC3035 /DB_XREF=gi:13236511 /UG=Hs.22412 hypothetical protein MGC3035 /FL=gb:AL136758.1 gb:BC002420.1 gb:NM_024293.1 NM_024293 family with sequence similarity 134, member A FAM134A 79137 NM_024293 /// XM_005246848 /// XM_005246849 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218038_at NM_018035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018035.1 /DEF=Homo sapiens hypothetical protein FLJ10241 (FLJ10241), mRNA. /FEA=mRNA /GEN=FLJ10241 /PROD=hypothetical protein FLJ10241 /DB_XREF=gi:8922302 /UG=Hs.279851 hypothetical protein FLJ10241 /FL=gb:NM_018035.1 NM_018035 ATP5S-like ATP5SL 55101 NM_001167867 /// NM_001167868 /// NM_001167869 /// NM_001167870 /// NM_001167871 /// NM_018035 /// NR_030765 /// XM_006723258 0005739 // mitochondrion // inferred from electronic annotation 218039_at NM_016359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016359.1 /DEF=Homo sapiens clone HQ0310 PRO0310p1 (LOC51203), mRNA. /FEA=mRNA /GEN=LOC51203 /PROD=clone HQ0310 PRO0310p1 /DB_XREF=gi:7705950 /UG=Hs.279905 clone HQ0310 PRO0310p1 /FL=gb:AF305711.1 gb:BC001308.1 gb:AF290612.1 gb:AF090915.1 gb:NM_016359.1 NM_016359 nucleolar and spindle associated protein 1 NUSAP1 51203 NM_001129897 /// NM_001243142 /// NM_001243143 /// NM_001243144 /// NM_016359 /// NM_018454 /// XM_005254428 /// XM_005254429 /// XM_005254430 /// XM_005254431 /// XM_006720559 /// XM_006720560 /// XM_006720561 /// XM_006720562 /// XM_006720563 0000070 // mitotic sister chromatid segregation // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000281 // mitotic cytokinesis // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0040001 // establishment of mitotic spindle localization // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218040_at NM_018061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018061.1 /DEF=Homo sapiens hypothetical protein FLJ10330 (FLJ10330), mRNA. /FEA=mRNA /GEN=FLJ10330 /PROD=hypothetical protein FLJ10330 /DB_XREF=gi:8922357 /UG=Hs.302267 hypothetical protein FLJ10330 /FL=gb:NM_018061.1 NM_018061 pre-mRNA processing factor 38B PRPF38B 55119 NM_018061 /// NR_037185 /// XM_006710726 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 218041_x_at NM_018573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018573.1 /DEF=Homo sapiens hypothetical protein PRO1068 (PRO1068), mRNA. /FEA=mRNA /GEN=PRO1068 /PROD=hypothetical protein PRO1068 /DB_XREF=gi:8924006 /UG=Hs.321158 hypothetical protein PRO1068 /FL=gb:AF116620.1 gb:NM_018573.1 NM_018573 solute carrier family 38, member 2 SLC38A2 54407 NM_018976 /// XM_005268983 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 218042_at NM_016129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016129.1 /DEF=Homo sapiens COP9 complex subunit 4 (LOC51138), mRNA. /FEA=mRNA /GEN=LOC51138 /PROD=COP9 complex subunit 4 /DB_XREF=gi:7705844 /UG=Hs.6671 COP9 complex subunit 4 /FL=gb:BC004302.1 gb:AF100757.1 gb:NM_016129.1 NM_016129 COP9 signalosome subunit 4 COPS4 51138 NM_001258006 /// NM_016129 0000338 // protein deneddylation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218043_s_at NM_022461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022461.1 /DEF=Homo sapiens hypothetical protein FLJ21939 similar to 5-azacytidine induced gene 2 (FLJ21939), mRNA. /FEA=mRNA /GEN=FLJ21939 /PROD=hypothetical protein FLJ21939 similar to5-azacytidine induced gene 2 /DB_XREF=gi:11968002 /UG=Hs.164478 hypothetical protein FLJ21939 similar to 5-azacytidine induced gene 2 /FL=gb:NM_022461.1 NM_022461 5-azacytidine induced 2 AZI2 64343 NM_001134432 /// NM_001134433 /// NM_001271650 /// NM_022461 /// XM_005265392 /// XM_005265393 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218044_x_at M24398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:M24398.1 /DEF=Human parathymosin mRNA, complete cds. /FEA=mRNA /GEN=PTMS /DB_XREF=gi:339698 /UG=Hs.171814 parathymosin /FL=gb:M24398.1 gb:NM_002824.1 M24398 parathymosin PTMS 5763 NM_002824 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement 0005634 // nucleus // traceable author statement 218045_x_at NM_002824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002824.1 /DEF=Homo sapiens parathymosin (PTMS), mRNA. /FEA=mRNA /GEN=PTMS /PROD=parathymosin /DB_XREF=gi:4506278 /UG=Hs.171814 parathymosin /FL=gb:M24398.1 gb:NM_002824.1 NM_002824 parathymosin PTMS 5763 NM_002824 0002376 // immune system process // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement 0005634 // nucleus // traceable author statement 218046_s_at NM_016065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016065.1 /DEF=Homo sapiens CGI-132 protein (LOC51021), mRNA. /FEA=mRNA /GEN=LOC51021 /PROD=CGI-132 protein /DB_XREF=gi:7705625 /UG=Hs.180312 CGI-132 protein /FL=gb:AF151890.1 gb:NM_016065.1 NM_016065 mitochondrial ribosomal protein S16 MRPS16 51021 NM_016065 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218047_at NM_024586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024586.1 /DEF=Homo sapiens hypothetical protein FLJ12492 (FLJ12492), mRNA. /FEA=mRNA /GEN=FLJ12492 /PROD=hypothetical protein FLJ12492 /DB_XREF=gi:13375771 /UG=Hs.21938 hypothetical protein FLJ12492 /FL=gb:NM_024586.1 NM_024586 oxysterol binding protein-like 9 OSBPL9 114883 NM_024586 /// NM_148904 /// NM_148905 /// NM_148906 /// NM_148907 /// NM_148908 /// NM_148909 /// NR_036662 /// XM_006710318 /// XM_006710319 /// XM_006710320 /// XM_006710321 /// XM_006710322 /// XM_006710323 /// XM_006710324 /// XM_006710325 /// XM_006710326 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 218048_at NM_012071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012071.1 /DEF=Homo sapiens BUP protein (BUP), mRNA. /FEA=mRNA /GEN=BUP /PROD=BUP protein /DB_XREF=gi:6912277 /UG=Hs.35660 BUP protein /FL=gb:AF078848.1 gb:AF201948.1 gb:NM_012071.1 NM_012071 COMM domain containing 3 COMMD3 23412 NM_012071 0005515 // protein binding // inferred from physical interaction 218049_s_at NM_014078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014078.1 /DEF=Homo sapiens L13 protein (L13), mRNA. /FEA=mRNA /GEN=L13 /PROD=L13 protein /DB_XREF=gi:7662495 /UG=Hs.43946 L13 protein /FL=gb:AF112214.1 gb:NM_014078.1 NM_014078 mitochondrial ribosomal protein L13 MRPL13 28998 NM_014078 /// XM_006716547 0006412 // translation // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218050_at NM_016617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016617.1 /DEF=Homo sapiens hypothetical protein (BM-002), mRNA. /FEA=mRNA /GEN=BM-002 /PROD=hypothetical protein /DB_XREF=gi:7705299 /UG=Hs.5862 hypothetical protein /FL=gb:BC005193.1 gb:AF208844.1 gb:NM_016617.1 NM_016617 ubiquitin-fold modifier 1 UFM1 51569 NM_001286703 /// NM_001286704 /// NM_001286705 /// NM_001286706 /// NM_016617 /// NR_104584 /// NR_104585 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0071569 // protein ufmylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 218051_s_at NM_022908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022908.1 /DEF=Homo sapiens hypothetical protein FLJ12442 (FLJ12442), mRNA. /FEA=mRNA /GEN=FLJ12442 /PROD=hypothetical protein FLJ12442 /DB_XREF=gi:12597652 /UG=Hs.84753 hypothetical protein FLJ12442 /FL=gb:NM_022908.1 NM_022908 5'-nucleotidase domain containing 2 NT5DC2 64943 NM_001134231 /// NM_022908 /// XM_005265406 /// XM_006713303 /// XM_006713304 /// XM_006713305 0008152 // metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218052_s_at NM_020410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020410.1 /DEF=Homo sapiens CGI-152 protein (LOC57130), mRNA. /FEA=mRNA /GEN=LOC57130 /PROD=CGI-152 protein /DB_XREF=gi:9966896 /UG=Hs.9275 CGI-152 protein /FL=gb:AF288687.1 gb:NM_020410.1 NM_020410 ATPase type 13A1 ATP13A1 57130 NM_020410 /// XM_005259992 /// XM_005259993 /// XM_005259995 /// XR_430145 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218053_at NM_017892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017892.1 /DEF=Homo sapiens hypothetical protein FLJ20585 (FLJ20585), mRNA. /FEA=mRNA /GEN=FLJ20585 /PROD=hypothetical protein FLJ20585 /DB_XREF=gi:8923548 /UG=Hs.107213 hypothetical protein FLJ20585 /FL=gb:AF151059.1 gb:NM_017892.1 NM_017892 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) PRPF40A 55660 NM_017892 /// XM_005246676 /// XM_005246677 /// XM_005246678 /// XM_005246679 0006397 // mRNA processing // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 218054_s_at BC001080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001080.1 /DEF=Homo sapiens, clone MGC:2749, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2749) /DB_XREF=gi:12654500 /UG=Hs.108847 hypothetical protein MGC2749 /FL=gb:BC001080.1 gb:NM_024069.1 BC001080 KxDL motif containing 1 KXD1 79036 NM_001171948 /// NM_001171949 /// NM_024069 /// XM_005260073 /// XM_006722883 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity 0031083 // BLOC-1 complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 218055_s_at NM_018268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018268.1 /DEF=Homo sapiens hypothetical protein FLJ10904 (FLJ10904), mRNA. /FEA=mRNA /GEN=FLJ10904 /PROD=hypothetical protein FLJ10904 /DB_XREF=gi:8922759 /UG=Hs.16470 hypothetical protein FLJ10904 /FL=gb:NM_018268.1 NM_018268 WD repeat domain 41 WDR41 55255 NM_018268 /// XM_005248551 /// XM_005248552 /// XM_006714656 /// XR_427715 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218056_at NM_016561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016561.1 /DEF=Homo sapiens apoptosis regulator (LOC51283), mRNA. /FEA=mRNA /GEN=LOC51283 /PROD=apoptosis regulator /DB_XREF=gi:7706090 /UG=Hs.168159 apoptosis regulator /FL=gb:BC003054.1 gb:AF173003.1 gb:NM_016561.1 NM_016561 bifunctional apoptosis regulator BFAR 51283 NM_016561 /// XM_005255350 /// XM_006725196 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218057_x_at NM_006067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006067.1 /DEF=Homo sapiens neighbor of COX4 (NOC4), mRNA. /FEA=mRNA /GEN=NOC4 /PROD=neighbor of COX4 /DB_XREF=gi:5174614 /UG=Hs.173162 neighbor of COX4 /FL=gb:BC001472.1 gb:AF005888.1 gb:NM_006067.1 NM_006067 ER membrane protein complex subunit 8 EMC8 10328 NM_001142288 /// NM_006067 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 218058_at NM_014593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014593.1 /DEF=Homo sapiens CpG binding protein (CGBP), mRNA. /FEA=mRNA /GEN=CGBP /PROD=CpG binding protein /DB_XREF=gi:7656974 /UG=Hs.180933 CpG binding protein /FL=gb:AL136862.1 gb:AF149758.1 gb:NM_014593.1 gb:AB031069.1 NM_014593 CXXC finger protein 1 CXXC1 30827 NM_001101654 /// NM_014593 /// XM_006722446 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218059_at NM_016096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016096.1 /DEF=Homo sapiens HSPC038 protein (LOC51123), mRNA. /FEA=mRNA /GEN=LOC51123 /PROD=HSPC038 protein /DB_XREF=gi:7705816 /UG=Hs.23528 HSPC038 protein /FL=gb:AF275802.1 gb:AF275809.1 gb:AF125099.1 gb:NM_016096.1 NM_016096 zinc finger protein 706 ZNF706 51123 NM_001042510 /// NM_001267708 /// NM_001267709 /// NM_016096 0046872 // metal ion binding // inferred from electronic annotation 218060_s_at NM_024598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024598.1 /DEF=Homo sapiens hypothetical protein FLJ13154 (FLJ13154), mRNA. /FEA=mRNA /GEN=FLJ13154 /PROD=hypothetical protein FLJ13154 /DB_XREF=gi:13375796 /UG=Hs.25303 hypothetical protein FLJ13154 /FL=gb:BC004415.1 gb:NM_024598.1 NM_024598 U6 snRNA biogenesis 1 USB1 79650 NM_001195302 /// NM_001204911 /// NM_024598 /// XM_005256144 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0034477 // U6 snRNA 3'-end processing // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218061_at NM_014623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014623.1 /DEF=Homo sapiens male-enhanced antigen (MEA), mRNA. /FEA=mRNA /GEN=MEA /PROD=male-enhanced antigen /DB_XREF=gi:7657325 /UG=Hs.278362 male-enhanced antigen /FL=gb:BC001754.1 gb:M27937.1 gb:L10400.1 gb:NM_014623.1 NM_014623 male-enhanced antigen 1 MEA1 4201 NM_014623 /// XM_005249121 /// XM_005249122 /// XM_005249123 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218062_x_at NM_012121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012121.2 /DEF=Homo sapiens Cdc42 effector protein 4; binder of Rho GTPases 4 (CEP4), mRNA. /FEA=mRNA /GEN=CEP4 /PROD=Cdc42 effector protein 4; binder of Rho GTPases4 /DB_XREF=gi:13786126 /UG=Hs.3903 Cdc42 effector protein 4; binder of Rho GTPases 4 /FL=gb:AB042237.1 gb:NM_012121.2 gb:AF099664.1 NM_012121 CDC42 effector protein (Rho GTPase binding) 4 CDC42EP4 23580 NM_012121 /// XM_005257182 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0017049 // GTP-Rho binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 218063_s_at AF099664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF099664.1 /DEF=Homo sapiens Cdc42 effector protein 4 mRNA, complete cds. /FEA=mRNA /PROD=Cdc42 effector protein 4 /DB_XREF=gi:4323349 /UG=Hs.3903 Cdc42 effector protein 4; binder of Rho GTPases 4 /FL=gb:AB042237.1 gb:NM_012121.2 gb:AF099664.1 AF099664 CDC42 effector protein (Rho GTPase binding) 4 CDC42EP4 23580 NM_012121 /// XM_005257182 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 218064_s_at NM_014371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014371.1 /DEF=Homo sapiens neighbor of A-kinase anchoring protein 95 (NAKAP95), mRNA. /FEA=mRNA /GEN=NAKAP95 /PROD=neighbor of A-kinase anchoring protein 95 /DB_XREF=gi:7657354 /UG=Hs.96200 neighbor of A-kinase anchoring protein 95 /FL=gb:BC000713.1 gb:AB025905.1 gb:NM_014371.1 gb:AF199414.1 NM_014371 A kinase (PRKA) anchor protein 8-like AKAP8L 26993 NM_001291478 /// NM_014371 /// NR_111971 /// XM_005259854 /// XR_244065 /// XR_244066 /// XR_430135 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0017151 // DEAD/H-box RNA helicase binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218065_s_at NM_020644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020644.1 /DEF=Homo sapiens chromosome 11 open reading frame 15 (C11ORF15), mRNA. /FEA=mRNA /GEN=C11ORF15 /PROD=chromosome 11 open reading frame 15 /DB_XREF=gi:11034854 /UG=Hs.121619 chromosome 11 open reading frame 15 /FL=gb:NM_020644.1 NM_020644 TMEM9 domain family, member B TMEM9B 56674 NM_001286094 /// NM_001286095 /// NM_020644 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype 218066_at NM_006598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006598.1 /DEF=Homo sapiens solute carrier family 12 (potassiumchloride transporters), member 7 (SLC12A7), mRNA. /FEA=mRNA /GEN=SLC12A7 /PROD=solute carrier family 12 (potassiumchloridetransporters), member 7 /DB_XREF=gi:5730042 /UG=Hs.172613 solute carrier family 12 (potassiumchloride transporters), member 7 /FL=gb:AF105365.1 gb:NM_006598.1 NM_006598 solute carrier family 12 (potassium/chloride transporter), member 7 SLC12A7 10723 NM_006598 /// XM_005248231 /// XM_006725006 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 218067_s_at NM_018011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018011.1 /DEF=Homo sapiens hypothetical protein FLJ10154 (FLJ10154), mRNA. /FEA=mRNA /GEN=FLJ10154 /PROD=hypothetical protein FLJ10154 /DB_XREF=gi:8922258 /UG=Hs.179972 hypothetical protein FLJ10154 /FL=gb:NM_018011.1 NM_018011 arginine and glutamate rich 1 ARGLU1 55082 NM_018011 /// XR_243043 /// XR_429268 /// XR_429269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218068_s_at NM_024836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024836.1 /DEF=Homo sapiens hypothetical protein FLJ22301 (FLJ22301), mRNA. /FEA=mRNA /GEN=FLJ22301 /PROD=hypothetical protein FLJ22301 /DB_XREF=gi:13376246 /UG=Hs.181406 hypothetical protein FLJ22301 /FL=gb:NM_024836.1 NM_024836 zinc finger protein 672 ZNF672 79894 NM_024836 /// XM_005270336 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218069_at NM_024096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024096.1 /DEF=Homo sapiens hypothetical protein MGC5627 (MGC5627), mRNA. /FEA=mRNA /GEN=MGC5627 /PROD=hypothetical protein MGC5627 /DB_XREF=gi:13129099 /UG=Hs.237971 hypothetical protein MGC5627 /FL=gb:BC001344.1 gb:NM_024096.1 gb:AF212242.1 NM_024096 dCTP pyrophosphatase 1 DCTPP1 79077 NM_024096 0009143 // nucleoside triphosphate catabolic process // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032556 // pyrimidine deoxyribonucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047429 // nucleoside-triphosphate diphosphatase activity // inferred from sequence or structural similarity /// 0047840 // dCTP diphosphatase activity // inferred from electronic annotation 218070_s_at NM_013335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013335.1 /DEF=Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), mRNA. /FEA=mRNA /GEN=GMPPA /PROD=GDP-mannose pyrophosphorylase A /DB_XREF=gi:11761616 /UG=Hs.27059 GDP-mannose pyrophosphorylase A /FL=gb:NM_013335.1 gb:AF135422.1 NM_013335 GDP-mannose pyrophosphorylase A GMPPA 29926 NM_013335 /// NM_205847 /// XM_005246483 /// XM_005246485 /// XM_005246486 /// XM_005246487 /// XR_241307 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004475 // mannose-1-phosphate guanylyltransferase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 218071_s_at NM_014160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014160.2 /DEF=Homo sapiens HSPC070 protein (HSPC070), mRNA. /FEA=mRNA /GEN=HSPC070 /PROD=HSPC070 protein /DB_XREF=gi:8850222 /UG=Hs.279474 HSPC070 protein /FL=gb:AF302084.1 gb:AF161555.2 gb:NM_014160.2 NM_014160 makorin ring finger protein 2 MKRN2 23609 NM_001271707 /// NM_014160 0016567 // protein ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218072_at NM_014186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014186.1 /DEF=Homo sapiens HSPC166 protein (HSPC166), mRNA. /FEA=mRNA /GEN=HSPC166 /PROD=HSPC166 protein /DB_XREF=gi:7661827 /UG=Hs.279836 HSPC166 protein /FL=gb:AL136688.1 gb:AF161515.1 gb:NM_014186.1 NM_014186 COMM domain containing 9 COMMD9 29099 NM_001101653 /// NM_014186 218073_s_at NM_018087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018087.1 /DEF=Homo sapiens hypothetical protein FLJ10407 (FLJ10407), mRNA. /FEA=mRNA /GEN=FLJ10407 /PROD=hypothetical protein FLJ10407 /DB_XREF=gi:8922408 /UG=Hs.30738 hypothetical protein FLJ10407 /FL=gb:BC003082.1 gb:NM_018087.1 NM_018087 NDC1 transmembrane nucleoporin NDC1 55706 NM_001168551 /// NM_018087 /// NR_033142 /// XM_006710762 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement /// 0031081 // nuclear pore distribution // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 218074_at NM_016062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016062.1 /DEF=Homo sapiens CGI-128 protein (LOC51647), mRNA. /FEA=mRNA /GEN=LOC51647 /PROD=CGI-128 protein /DB_XREF=gi:7706342 /UG=Hs.9825 CGI-128 protein /FL=gb:BC001733.1 gb:BC005023.1 gb:AF151886.1 gb:AF161467.1 gb:NM_016062.1 NM_016062 family with sequence similarity 96, member B FAM96B 51647 NM_016062 /// NR_024525 /// NR_046109 0007059 // chromosome segregation // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218075_at NM_015665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015665.1 /DEF=Homo sapiens aladin (AAAS), mRNA. /FEA=mRNA /GEN=AAAS /PROD=aladin /DB_XREF=gi:12962936 /UG=Hs.125262 aladin /FL=gb:BC000659.1 gb:NM_015665.1 gb:AF226048.1 NM_015665 achalasia, adrenocortical insufficiency, alacrimia AAAS 8086 NM_001173466 /// NM_015665 /// XM_006719617 /// XM_006719618 /// XM_006719619 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // non-traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218076_s_at NM_018054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018054.1 /DEF=Homo sapiens homolog of rat nadrin (FLJ10308), mRNA. /FEA=mRNA /GEN=FLJ10308 /PROD=homolog of rat nadrin /DB_XREF=gi:8922343 /UG=Hs.14169 homolog of rat nadrin /FL=gb:AF113218.1 gb:NM_018054.1 NM_018054 Rho GTPase activating protein 17 ARHGAP17 55114 NM_001006634 /// NM_018054 /// XM_005255413 /// XM_005255414 /// XM_006721057 /// XM_006721058 /// XM_006721059 /// XM_006721060 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 218077_s_at BE542551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE542551 /FEA=EST /DB_XREF=gi:9771196 /DB_XREF=est:601063935F1 /CLONE=IMAGE:3450249 /UG=Hs.14896 DHHC1 protein /FL=gb:AF247703.1 gb:NM_016598.1 BE542551 zinc finger, DHHC-type containing 3 ZDHHC3 51304 NM_001135179 /// NM_001135180 /// NM_016598 /// XM_005265209 /// XM_005265212 /// XM_006713189 /// XM_006713190 /// XM_006713191 /// XM_006713192 /// XM_006713193 /// XM_006713194 0006605 // protein targeting // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218078_s_at NM_016598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016598.1 /DEF=Homo sapiens DHHC1 protein (LOC51304), mRNA. /FEA=mRNA /GEN=LOC51304 /PROD=DHHC1 protein /DB_XREF=gi:7706132 /UG=Hs.14896 DHHC1 protein /FL=gb:AF247703.1 gb:NM_016598.1 NM_016598 zinc finger, DHHC-type containing 3 ZDHHC3 51304 NM_001135179 /// NM_001135180 /// NM_016598 /// XM_005265209 /// XM_005265212 /// XM_006713189 /// XM_006713190 /// XM_006713191 /// XM_006713192 /// XM_006713193 /// XM_006713194 0006605 // protein targeting // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218079_s_at NM_024835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024835.1 /DEF=Homo sapiens hypothetical protein FLJ22561 (FLJ22561), mRNA. /FEA=mRNA /GEN=FLJ22561 /PROD=hypothetical protein FLJ22561 /DB_XREF=gi:13376244 /UG=Hs.180799 hypothetical protein FLJ22561 /FL=gb:AF126964.1 gb:NM_024835.1 NM_024835 gametogenetin binding protein 2 GGNBP2 79893 NM_024835 /// XM_005257689 /// XM_005276909 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 218080_x_at NM_007051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007051.1 /DEF=Homo sapiens Fas (TNFRSF6) associated factor 1 (FAF1), mRNA. /FEA=mRNA /GEN=FAF1 /PROD=Fas (TNFRSF6) associated factor 1 /DB_XREF=gi:5901947 /UG=Hs.25821 Fas (TNFRSF6) associated factor 1 /FL=gb:BC004970.1 gb:AF132938.1 gb:AF106798.1 gb:NM_007051.1 NM_007051 Fas (TNFRSF6) associated factor 1 FAF1 11124 NM_007051 /// NM_131917 0006915 // apoptotic process // inferred from electronic annotation /// 0007253 // cytoplasmic sequestering of NF-kappaB // inferred from mutant phenotype /// 0008219 // cell death // inferred from mutant phenotype /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from mutant phenotype /// 0042176 // regulation of protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0045859 // regulation of protein kinase activity // non-traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0031265 // CD95 death-inducing signaling complex // non-traceable author statement /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019887 // protein kinase regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 218081_at NM_017874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017874.1 /DEF=Homo sapiens hypothetical protein FLJ20550 (FLJ20550), mRNA. /FEA=mRNA /GEN=FLJ20550 /PROD=hypothetical protein FLJ20550 /DB_XREF=gi:8923517 /UG=Hs.274422 hypothetical protein FLJ20550 /FL=gb:NM_017874.1 NM_017874 chromosome 20 open reading frame 27 C20orf27 54976 NM_001039140 /// NM_001258429 /// NM_001258430 /// NM_017874 /// NR_047675 218082_s_at NM_014517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014517.1 /DEF=Homo sapiens upstream binding protein 1 (LBP-1a) (UBP1), mRNA. /FEA=mRNA /GEN=UBP1 /PROD=upstream binding protein 1 (LBP-1a) /DB_XREF=gi:7657668 /UG=Hs.28423 upstream binding protein 1 (LBP-1a) /FL=gb:AF198487.1 gb:NM_014517.1 NM_014517 upstream binding protein 1 (LBP-1a) UBP1 7342 NM_001128160 /// NM_001128161 /// NM_014517 /// XM_006713322 /// XR_427288 /// XR_427289 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement 218083_at NM_025072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025072.1 /DEF=Homo sapiens hypothetical protein FLJ14038 (FLJ14038), mRNA. /FEA=mRNA /GEN=FLJ14038 /PROD=hypothetical protein FLJ14038 /DB_XREF=gi:13376616 /UG=Hs.288102 hypothetical protein FLJ14038 /FL=gb:NM_025072.1 NM_025072 prostaglandin E synthase 2 PTGES2 80142 NM_001256335 /// NM_025072 /// NM_198938 /// NM_198939 /// NM_198940 /// NR_027812 /// XM_005252239 0001516 // prostaglandin biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046903 // secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from sequence or structural similarity /// 0016853 // isomerase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0043295 // glutathione binding // inferred from sequence or structural similarity /// 0050220 // prostaglandin-E synthase activity // inferred from electronic annotation 218084_x_at NM_014164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014164.2 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 5 (FXYD5), mRNA. /FEA=mRNA /GEN=FXYD5 /PROD=related to ion channel /DB_XREF=gi:11612664 /UG=Hs.294135 FXYD domain-containing ion transport regulator 5 /FL=gb:NM_014164.2 gb:AF161462.1 NM_014164 FXYD domain containing ion transport regulator 5 FXYD5 53827 NM_001164605 /// NM_014164 /// NM_144779 /// NR_028406 /// XM_006723245 /// XM_006723246 /// XM_006723247 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0030033 // microvillus assembly // non-traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0046588 // negative regulation of calcium-dependent cell-cell adhesion // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from direct assay 218085_at NM_015961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015961.1 /DEF=Homo sapiens CGI-34 protein (LOC51612), mRNA. /FEA=mRNA /GEN=LOC51612 /PROD=CGI-34 protein /DB_XREF=gi:7706273 /UG=Hs.36237 CGI-34 protein /FL=gb:AF275810.1 gb:AF132968.1 gb:NM_015961.1 NM_015961 charged multivesicular body protein 5 CHMP5 51510 NM_001195536 /// NM_016410 0001919 // regulation of receptor recycling // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218086_at NM_015392 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015392.1 /DEF=Homo sapiens neural proliferation, differentiation and control, 1 (NPDC1), mRNA. /FEA=mRNA /GEN=NPDC1 /PROD=neural proliferation, differentiation andcontrol, 1 /DB_XREF=gi:10181099 /UG=Hs.105547 neural proliferation, differentiation and control, 1 /FL=gb:NM_015392.1 gb:BC004217.1 gb:AF285836.1 gb:AF272357.1 NM_015392 neural proliferation, differentiation and control, 1 NPDC1 56654 NM_015392 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218087_s_at NM_015385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015385.1 /DEF=Homo sapiens SH3-domain protein 5 (ponsin) (SH3D5), mRNA. /FEA=mRNA /GEN=SH3D5 /PROD=ponsin /DB_XREF=gi:7661699 /UG=Hs.108924 SH3-domain protein 5 (ponsin) /FL=gb:AL117472.1 gb:NM_015385.1 NM_015385 sorbin and SH3 domain containing 1 SORBS1 10580 NM_001034954 /// NM_001034955 /// NM_001034956 /// NM_001034957 /// NM_001290294 /// NM_001290295 /// NM_001290296 /// NM_001290297 /// NM_001290298 /// NM_006434 /// NM_015385 /// NM_024991 /// XM_005269404 /// XM_005269405 /// XM_005269406 /// XM_005269411 /// XM_005269412 /// XM_005269414 /// XM_005269424 /// XM_005269425 /// XM_005269427 /// XM_005269431 /// XM_005269437 /// XM_005269439 /// XM_005269440 /// XM_006717560 /// XM_006717561 /// XM_006717562 /// XM_006717563 /// XM_006717564 /// XM_006717565 /// XM_006717566 /// XM_006717567 /// XM_006717568 /// XM_006717569 /// XM_006717570 /// XM_006717571 /// XM_006717572 /// XM_006717573 /// XM_006717574 /// XM_006717575 /// XM_006717576 /// XM_006717577 /// XM_006717578 /// XM_006717579 /// XM_006717580 /// XM_006717581 /// XM_006717582 /// XM_006717583 /// XM_006717584 /// XM_006717585 /// XM_006717586 /// XM_006717587 /// XM_006717588 /// XM_006717589 /// XM_006717590 /// XM_006717591 /// XM_006717592 /// XM_006717593 /// XM_006717594 /// XM_006717595 0006810 // transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred by curator /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0015758 // glucose transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from sequence or structural similarity /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005899 // insulin receptor complex // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from sequence or structural similarity /// 0005915 // zonula adherens // traceable author statement /// 0005924 // cell-substrate adherens junction // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0003779 // actin binding // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // inferred by curator /// 0005070 // SH3/SH2 adaptor activity // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation 218088_s_at NM_022157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022157.1 /DEF=Homo sapiens Rag C protein (GTR2), mRNA. /FEA=mRNA /GEN=GTR2 /PROD=Rag C protein /DB_XREF=gi:11995471 /UG=Hs.110950 Rag C protein /FL=gb:AF272035.1 gb:NM_022157.1 gb:AF323609.1 NM_022157 Ras-related GTP binding C RRAGC 64121 NM_001271851 /// NM_022157 0006184 // GTP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008380 // RNA splicing // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // non-traceable author statement /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 218089_at NM_015511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015511.1 /DEF=Homo sapiens DKFZP564N1363 protein (DKFZP564N1363), mRNA. /FEA=mRNA /GEN=DKFZP564N1363 /PROD=DKFZP564N1363 protein /DB_XREF=gi:7661627 /UG=Hs.11314 DKFZP564N1363 protein /FL=gb:BC001751.1 gb:AF132957.1 gb:AL117419.1 gb:AF113672.1 gb:NM_015511.1 NM_015511 AAR2 splicing factor homolog (S. cerevisiae) AAR2 25980 NM_001271874 /// NM_015511 /// XM_005260385 /// XM_006723770 218090_s_at NM_018117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018117.8 /DEF=Homo sapiens WD40 repeat domain 11 protein (WDR11), mRNA. /FEA=mRNA /GEN=WDR11 /PROD=WD40 repeat domain 11 protein /DB_XREF=gi:13324687 /UG=Hs.16677 WD repeat domain 15 /FL=gb:AF320223.1 gb:NM_018117.8 NM_018117 WD repeat domain 11 WDR11 55717 NM_018117 /// XM_005269962 /// XM_005269963 /// XM_005269964 /// XR_246098 /// XR_428707 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218091_at AI989512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI989512 /FEA=EST /DB_XREF=gi:5836393 /DB_XREF=est:ws25f10.x1 /CLONE=IMAGE:2498251 /UG=Hs.171545 HIV-1 Rev binding protein /FL=gb:NM_004504.2 AI989512 ArfGAP with FG repeats 1 AGFG1 3267 NM_001135187 /// NM_001135188 /// NM_001135189 /// NM_004504 /// XM_005246516 /// XM_006712478 /// XM_006712479 /// XM_006712480 /// XM_006712481 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218092_s_at NM_004504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004504.2 /DEF=Homo sapiens HIV-1 Rev binding protein (HRB), mRNA. /FEA=mRNA /GEN=HRB /PROD=HIV-1 Rev binding protein /DB_XREF=gi:7262381 /UG=Hs.171545 HIV-1 Rev binding protein /FL=gb:NM_004504.2 NM_004504 ArfGAP with FG repeats 1 AGFG1 3267 NM_001135187 /// NM_001135188 /// NM_001135189 /// NM_004504 /// XM_005246516 /// XM_006712478 /// XM_006712479 /// XM_006712480 /// XM_006712481 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218093_s_at NM_017664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017664.1 /DEF=Homo sapiens hypothetical protein FLJ20093 (FLJ20093), mRNA. /FEA=mRNA /GEN=FLJ20093 /PROD=hypothetical protein FLJ20093 /DB_XREF=gi:8923103 /UG=Hs.172572 hypothetical protein FLJ20093 /FL=gb:NM_017664.1 NM_017664 ankyrin repeat domain 10 ANKRD10 55608 NM_001286721 /// NM_017664 /// NR_104586 /// NR_104587 0005515 // protein binding // inferred from electronic annotation 218094_s_at NM_018478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018478.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HSMNP1 (HSMNP1), mRNA. /FEA=mRNA /GEN=HSMNP1 /PROD=uncharacterized hypothalamus protein HSMNP1 /DB_XREF=gi:8923782 /UG=Hs.179666 uncharacterized hypothalamus protein HSMNP1 /FL=gb:BC001105.1 gb:AF220191.1 gb:NM_018478.1 NM_018478 dysbindin (dystrobrevin binding protein 1) domain containing 2 /// Sys1 golgi trafficking protein /// SYS1-DBNDD2 readthrough (NMD candidate) DBNDD2 /// SYS1 /// SYS1-DBNDD2 55861 /// 90196 /// 767557 NM_001048221 /// NM_001048222 /// NM_001048223 /// NM_001048224 /// NM_001048225 /// NM_001048226 /// NM_001099791 /// NM_001197129 /// NM_001197139 /// NM_001197140 /// NM_018478 /// NM_033542 /// NR_003189 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218095_s_at NM_018475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018475.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HTMP (LOC55858), mRNA. /FEA=mRNA /GEN=LOC55858 /PROD=uncharacterized hypothalamus protein HTMP /DB_XREF=gi:8923860 /UG=Hs.236510 uncharacterized hypothalamus protein HTMP /FL=gb:BC003545.1 gb:AF220188.1 gb:NM_018475.1 gb:AF183409.1 NM_018475 transmembrane protein 165 TMEM165 55858 NM_018475 /// NR_073070 /// XR_427522 0006487 // protein N-linked glycosylation // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from genetic interaction /// 0032472 // Golgi calcium ion transport // inferred from direct assay /// 0035751 // regulation of lysosomal lumen pH // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 218096_at NM_018361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018361.1 /DEF=Homo sapiens hypothetical protein FLJ11210 (FLJ11210), mRNA. /FEA=mRNA /GEN=FLJ11210 /PROD=hypothetical protein FLJ11210 /DB_XREF=gi:8922941 /UG=Hs.27842 hypothetical protein FLJ11210 /FL=gb:NM_018361.1 NM_018361 1-acylglycerol-3-phosphate O-acyltransferase 5 AGPAT5 55326 NM_018361 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006639 // acylglycerol metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 218097_s_at NM_024040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024040.1 /DEF=Homo sapiens hypothetical protein MGC2491 (MGC2491), mRNA. /FEA=mRNA /GEN=MGC2491 /PROD=hypothetical protein MGC2491 /DB_XREF=gi:13128995 /UG=Hs.11270 hypothetical protein MGC2491 /FL=gb:BC000262.1 gb:NM_024040.1 NM_024040 CUE domain containing 2 CUEDC2 79004 NM_024040 /// XM_005270147 /// XR_428716 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218098_at AL121903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121903 /DEF=Human DNA sequence from clone RP1-155G6 on chromosome 20 Contains part of the gene for brefeldin A-inhibited guanine nucleotide-exchange protein 2, part of the gene for CSE1L (chromosome segregation 1 (yeast homolog)-like), ESTs, STSs, GSSs and a... /FEA=mRNA /DB_XREF=gi:7330682 /UG=Hs.118249 brefeldin A-inhibited guanine nucleotide-exchange protein 2 /FL=gb:AF084521.1 gb:NM_006420.1 AL121903 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) ARFGEF2 10564 NM_006420 /// XM_005260252 /// XM_006723683 0001881 // receptor recycling // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from mutant phenotype /// 0007032 // endosome organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005879 // axonemal microtubule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0032279 // asymmetric synapse // inferred from sequence or structural similarity /// 0032280 // symmetric synapse // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from sequence or structural similarity 218099_at NM_018469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018469.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT008 (HT008), mRNA. /FEA=mRNA /GEN=HT008 /PROD=uncharacterized hypothalamus protein HT008 /DB_XREF=gi:8923803 /UG=Hs.16206 uncharacterized hypothalamus protein HT008 /FL=gb:AF220182.1 gb:NM_018469.1 NM_018469 testis expressed 2 TEX2 55852 NM_001288732 /// NM_001288733 /// NM_018469 /// XM_005257507 0006665 // sphingolipid metabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0021859 // pyramidal neuron differentiation // inferred from electronic annotation 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005543 // phospholipid binding // inferred from electronic annotation 218100_s_at NM_018010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018010.1 /DEF=Homo sapiens hypothetical protein FLJ10147 (FLJ10147), mRNA. /FEA=mRNA /GEN=FLJ10147 /PROD=hypothetical protein FLJ10147 /DB_XREF=gi:8922255 /UG=Hs.170318 hypothetical protein FLJ10147 /FL=gb:AF139576.1 gb:AF245220.1 gb:NM_018010.1 NM_018010 intraflagellar transport 57 homolog (Chlamydomonas) IFT57 55081 NM_018010 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044292 // dendrite terminus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218101_s_at NM_004549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004549.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2 (14.5kD, B14.5b) (NDUFC2), mRNA. /FEA=mRNA /GEN=NDUFC2 /PROD=NADH dehydrogenase (ubiquinone) 1, subcomplexunknown, 2 (14.5kD, B14.5b) /DB_XREF=gi:4758783 /UG=Hs.193313 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2 (14.5kD, B14.5b) /FL=gb:AF087659.1 gb:AF070652.1 gb:NM_004549.1 NM_004549 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa /// NDUFC2-KCTD14 readthrough NDUFC2 /// NDUFC2-KCTD14 4718 /// 100532726 NM_001203260 /// NM_001203261 /// NM_001203262 /// NM_001204054 /// NM_001204055 /// NM_004549 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation 218102_at NM_015954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015954.1 /DEF=Homo sapiens CGI-26 protein (LOC51071), mRNA. /FEA=mRNA /GEN=LOC51071 /PROD=CGI-26 protein /DB_XREF=gi:7705717 /UG=Hs.24332 CGI-26 protein /FL=gb:AF132960.1 gb:NM_015954.1 NM_015954 deoxyribose-phosphate aldolase (putative) DERA 51071 NM_015954 /// XM_006719083 0009264 // deoxyribonucleotide catabolic process // inferred from electronic annotation /// 0046121 // deoxyribonucleoside catabolic process // inferred from direct assay /// 0046386 // deoxyribose phosphate catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004139 // deoxyribose-phosphate aldolase activity // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation 218103_at NM_017647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017647.1 /DEF=Homo sapiens hypothetical protein FLJ20062 (FLJ20062), mRNA. /FEA=mRNA /GEN=FLJ20062 /PROD=hypothetical protein FLJ20062 /DB_XREF=gi:8923066 /UG=Hs.257486 hypothetical protein FLJ20062 /FL=gb:BC000131.1 gb:NM_017647.1 NM_017647 FtsJ homolog 3 (E. coli) FTSJ3 117246 NM_017647 0000453 // enzyme-directed rRNA 2'-O-methylation // inferred from electronic annotation /// 0001510 // RNA methylation // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030688 // preribosome, small subunit precursor // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218104_at NM_017746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017746.1 /DEF=Homo sapiens hypothetical protein FLJ20287 (FLJ20287), mRNA. /FEA=mRNA /GEN=FLJ20287 /PROD=hypothetical protein FLJ20287 /DB_XREF=gi:8923268 /UG=Hs.26369 hypothetical protein FLJ20287 /FL=gb:NM_017746.1 NM_017746 testis expressed 10 TEX10 54881 NM_001161584 /// NM_017746 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218105_s_at NM_015956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015956.1 /DEF=Homo sapiens CGI-28 protein (LOC51073), mRNA. /FEA=mRNA /GEN=LOC51073 /PROD=CGI-28 protein /DB_XREF=gi:7705721 /UG=Hs.279652 CGI-28 protein /FL=gb:AF132962.1 gb:NM_015956.1 NM_015956 mitochondrial ribosomal protein L4 MRPL4 51073 NM_015956 /// NM_146387 /// NM_146388 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218106_s_at NM_018141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018141.1 /DEF=Homo sapiens hypothetical protein FLJ10567 (FLJ10567), mRNA. /FEA=mRNA /GEN=FLJ10567 /PROD=hypothetical protein FLJ10567 /DB_XREF=gi:8922522 /UG=Hs.28444 hypothetical protein FLJ10567 /FL=gb:AF113220.1 gb:NM_018141.1 NM_018141 mitochondrial ribosomal protein S10 MRPS10 55173 NM_018141 /// XM_005249206 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 218107_at NM_025160 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025160.1 /DEF=Homo sapiens hypothetical protein FLJ21016 (FLJ21016), mRNA. /FEA=mRNA /GEN=FLJ21016 /PROD=hypothetical protein FLJ21016 /DB_XREF=gi:13376760 /UG=Hs.289069 hypothetical protein FLJ21016 /FL=gb:NM_025160.1 NM_025160 WD repeat domain 26 WDR26 80232 NM_001115113 /// NM_025160 /// XM_005273273 /// XM_006711817 /// XR_247043 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218108_at NM_018108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018108.1 /DEF=Homo sapiens hypothetical protein FLJ10483 (FLJ10483), mRNA. /FEA=mRNA /GEN=FLJ10483 /PROD=hypothetical protein FLJ10483 /DB_XREF=gi:8922451 /UG=Hs.6877 hypothetical protein FLJ10483 /FL=gb:NM_018108.1 NM_018108 ubiquitin protein ligase E3 component n-recognin 7 (putative) UBR7 55148 NM_001100417 /// NM_175748 /// NR_038150 0016567 // protein ubiquitination // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218109_s_at NM_022736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022736.1 /DEF=Homo sapiens hypothetical protein FLJ14153 (FLJ14153), mRNA. /FEA=mRNA /GEN=FLJ14153 /PROD=hypothetical protein FLJ14153 /DB_XREF=gi:12232392 /UG=Hs.7503 hypothetical protein FLJ14153 /FL=gb:NM_022736.1 gb:AB014732.1 NM_022736 major facilitator superfamily domain containing 1 MFSD1 64747 NM_001167903 /// NM_001289406 /// NM_001289407 /// NM_022736 /// NR_110328 /// XM_006713730 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218110_at NM_020196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020196.1 /DEF=Homo sapiens HCNP protein; XPA-binding protein 2 (HCNP), mRNA. /FEA=mRNA /GEN=HCNP /PROD=HCNP protein; XPA-binding protein 2 /DB_XREF=gi:9910259 /UG=Hs.9822 HCNP protein; XPA-binding protein 2 /FL=gb:AB026111.1 gb:AF226051.1 gb:NM_020196.1 NM_020196 XPA binding protein 2 XAB2 56949 NM_020196 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001824 // blastocyst development // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218111_s_at NM_018686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018686.1 /DEF=Homo sapiens CMP-N-acetylneuraminic acid synthase (LOC55907), mRNA. /FEA=mRNA /GEN=LOC55907 /PROD=CMP-N-acetylneuraminic acid synthase /DB_XREF=gi:8923899 /UG=Hs.12492 CMP-N-acetylneuraminic acid synthase /FL=gb:AF271388.1 gb:NM_018686.1 NM_018686 cytidine monophosphate N-acetylneuraminic acid synthetase CMAS 55907 NM_018686 0006054 // N-acetylneuraminate metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0008781 // N-acylneuraminate cytidylyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 218112_at NM_023936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023936.1 /DEF=Homo sapiens hypothetical protein MGC2616 (MGC2616), mRNA. /FEA=mRNA /GEN=MGC2616 /PROD=hypothetical protein MGC2616 /DB_XREF=gi:13027603 /UG=Hs.157160 hypothetical protein MGC2616 /FL=gb:BC001182.1 gb:NM_023936.1 NM_023936 mitochondrial ribosomal protein S34 MRPS34 65993 NM_023936 /// XM_005255511 /// XM_005255512 0005739 // mitochondrion // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 218113_at NM_013390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013390.1 /DEF=Homo sapiens transmembrane protein 2 (TMEM2), mRNA. /FEA=mRNA /GEN=TMEM2 /PROD=transmembrane protein 2 /DB_XREF=gi:7019554 /UG=Hs.160417 transmembrane protein 2 /FL=gb:AF137030.1 gb:NM_013390.1 NM_013390 transmembrane protein 2 TMEM2 23670 NM_001135820 /// NM_013390 /// XM_005251869 /// XM_006717033 0007275 // multicellular organismal development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 218114_at NM_013365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013365.1 /DEF=Homo sapiens ADP-ribosylation factor binding protein GGA1 (GGA1), mRNA. /FEA=mRNA /GEN=GGA1 /PROD=ADP-ribosylation factor binding protein GGA1 /DB_XREF=gi:9558728 /UG=Hs.238296 ADP-ribosylation factor binding protein GGA1 /FL=gb:AF190862.1 gb:AF233521.1 gb:AF218584.1 gb:NM_013365.1 NM_013365 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 GGA1 26088 NM_001001560 /// NM_001001561 /// NM_001172687 /// NM_001172688 /// NM_013365 /// XM_005261517 /// XM_005261518 /// XM_005261520 /// XM_005261522 /// XM_006724228 /// XM_006724229 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218115_at NM_018154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018154.1 /DEF=Homo sapiens hypothetical protein FLJ10604 (FLJ10604), mRNA. /FEA=mRNA /GEN=FLJ10604 /PROD=hypothetical protein FLJ10604 /DB_XREF=gi:8922548 /UG=Hs.26516 hypothetical protein FLJ10604 /FL=gb:NM_018154.1 NM_018154 anti-silencing function 1B histone chaperone ASF1B 55723 NM_018154 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from electronic annotation 218116_at NM_016520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016520.1 /DEF=Homo sapiens hepatocellular carcinoma-associated antigen 59 (LOC51759), mRNA. /FEA=mRNA /GEN=LOC51759 /PROD=hepatocellular carcinoma-associated antigen 59 /DB_XREF=gi:7706556 /UG=Hs.278429 hepatocellular carcinoma-associated antigen 59 /FL=gb:AF151054.1 gb:AF218421.1 gb:NM_016482.1 gb:NM_016520.1 NM_016520 chromosome 9 open reading frame 78 C9orf78 51759 NM_016520 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 218117_at NM_014248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014248.1 /DEF=Homo sapiens ring-box 1 (RBX1), mRNA. /FEA=mRNA /GEN=RBX1 /PROD=ring-box 1 /DB_XREF=gi:7657507 /UG=Hs.279919 ring-box 1 /FL=gb:BC001466.1 gb:AF140598.1 gb:AF142059.1 gb:NM_014248.1 NM_014248 ring-box 1, E3 ubiquitin protein ligase RBX1 9978 NM_014248 0006281 // DNA repair // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045116 // protein neddylation // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from sequence or structural similarity /// 0030891 // VCB complex // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from direct assay /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019788 // NEDD8 ligase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218118_s_at NM_006327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006327.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 23 (yeast) homolog (TIM23), mRNA. /FEA=mRNA /GEN=TIM23 /PROD=translocase of inner mitochondrial membrane 23(yeast) homolog /DB_XREF=gi:5454121 /UG=Hs.283684 translocase of inner mitochondrial membrane 23 (yeast) homolog /FL=gb:AF030162.1 gb:NM_006327.1 NM_006327 translocase of inner mitochondrial membrane 23 homolog (yeast) /// translocase of inner mitochondrial membrane 23 homolog B (yeast) TIMM23 /// TIMM23B 100287932 /// 100652748 NM_001290117 /// NM_001290118 /// NM_006327 /// NR_073029 /// NR_073030 /// NR_110767 /// XM_005278340 /// XM_006710232 /// XM_006718099 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0004649 // poly(ADP-ribose) glycohydrolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218119_at NM_006327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006327.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 23 (yeast) homolog (TIM23), mRNA. /FEA=mRNA /GEN=TIM23 /PROD=translocase of inner mitochondrial membrane 23(yeast) homolog /DB_XREF=gi:5454121 /UG=Hs.283684 translocase of inner mitochondrial membrane 23 (yeast) homolog /FL=gb:AF030162.1 gb:NM_006327.1 NM_006327 translocase of inner mitochondrial membrane 23 homolog (yeast) /// translocase of inner mitochondrial membrane 23 homolog B (yeast) TIMM23 /// TIMM23B 100287932 /// 100652748 NM_001290117 /// NM_001290118 /// NM_006327 /// NR_073029 /// NR_073030 /// NR_110767 /// XM_005278340 /// XM_006710232 /// XM_006718099 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0004649 // poly(ADP-ribose) glycohydrolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218120_s_at D21243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D21243.1 /DEF=Human mRNA for heme oxygenase-2, complete cds. /FEA=mRNA /PROD=heme oxygenase-2 /DB_XREF=gi:416226 /UG=Hs.284279 heme oxygenase (decycling) 2 /FL=gb:BC002396.1 gb:D21243.1 gb:NM_002134.2 D21243 heme oxygenase (decycling) 2 HMOX2 3163 NM_001127204 /// NM_001127205 /// NM_001127206 /// NM_001286267 /// NM_001286268 /// NM_001286269 /// NM_001286270 /// NM_001286271 /// NM_002134 0001666 // response to hypoxia // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006788 // heme oxidation // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004392 // heme oxygenase (decyclizing) activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218121_at NM_002134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002134.2 /DEF=Homo sapiens heme oxygenase (decycling) 2 (HMOX2), mRNA. /FEA=mRNA /GEN=HMOX2 /PROD=heme oxygenase (decyclizing) 2 /DB_XREF=gi:8051607 /UG=Hs.284279 heme oxygenase (decycling) 2 /FL=gb:BC002396.1 gb:D21243.1 gb:NM_002134.2 NM_002134 heme oxygenase (decycling) 2 HMOX2 3163 NM_001127204 /// NM_001127205 /// NM_001127206 /// NM_001286267 /// NM_001286268 /// NM_001286269 /// NM_001286270 /// NM_001286271 /// NM_002134 0001666 // response to hypoxia // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006788 // heme oxidation // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004392 // heme oxygenase (decyclizing) activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218122_s_at NM_021627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021627.1 /DEF=Homo sapiens sentrin-specific protease (SENP2), mRNA. /FEA=mRNA /GEN=SENP2 /PROD=sentrin-specific protease /DB_XREF=gi:11055993 /UG=Hs.3355 sentrin-specific protease /FL=gb:AF151697.2 gb:NM_021627.1 NM_021627 SUMO1/sentrin/SMT3 specific peptidase 2 SENP2 59343 NM_021627 /// XM_005247690 /// XM_005247691 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0016926 // protein desumoylation // inferred from sequence or structural similarity /// 0030111 // regulation of Wnt signaling pathway // non-traceable author statement /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032875 // regulation of DNA endoreduplication // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 218123_at NM_017835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017835.1 /DEF=Homo sapiens chromosome 21 open reading frame 59 (C21ORF59), mRNA. /FEA=mRNA /GEN=C21ORF59 /PROD=hypothetical protein FLJ20467 /DB_XREF=gi:8923436 /UG=Hs.5811 chromosome 21 open reading frame 59 /FL=gb:NM_021254.1 gb:BC000709.1 gb:NM_017835.1 gb:AF282851.1 NM_017835 chromosome 21 open reading frame 59 C21orf59 56683 NM_017835 /// NM_021254 /// NR_036552 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 218124_at NM_017750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017750.1 /DEF=Homo sapiens hypothetical protein FLJ20296 (FLJ20296), mRNA. /FEA=mRNA /GEN=FLJ20296 /PROD=hypothetical protein FLJ20296 /DB_XREF=gi:8923274 /UG=Hs.6603 hypothetical protein FLJ20296 /FL=gb:NM_017750.1 NM_017750 retinol saturase (all-trans-retinol 13,14-reductase) RETSAT 54884 NM_017750 0042572 // retinol metabolic process // not recorded /// 0042572 // retinol metabolic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from sequence or structural similarity 0016491 // oxidoreductase activity // inferred from sequence or structural similarity /// 0051786 // all-trans-retinol 13,14-reductase activity // not recorded /// 0051786 // all-trans-retinol 13,14-reductase activity // inferred from sequence or structural similarity 218125_s_at NM_018246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018246.1 /DEF=Homo sapiens hypothetical protein FLJ10853 (FLJ10853), mRNA. /FEA=mRNA /GEN=FLJ10853 /PROD=hypothetical protein FLJ10853 /DB_XREF=gi:8922717 /UG=Hs.72085 hypothetical protein FLJ10853 /FL=gb:NM_018246.1 NM_018246 coiled-coil domain containing 25 CCDC25 55246 NM_018246 /// XM_005273563 0070062 // extracellular vesicular exosome // inferred from direct assay 218126_at NM_018145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018145.1 /DEF=Homo sapiens hypothetical protein FLJ10579 (FLJ10579), mRNA. /FEA=mRNA /GEN=FLJ10579 /PROD=hypothetical protein FLJ10579 /DB_XREF=gi:8922531 /UG=Hs.8055 hypothetical protein FLJ10579 /FL=gb:NM_018145.1 NM_018145 regulator of microtubule dynamics 3 RMDN3 55177 NM_018145 /// XM_005254531 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218127_at AI804118 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI804118 /FEA=EST /DB_XREF=gi:5369590 /DB_XREF=est:tc68e01.x1 /CLONE=IMAGE:2069784 /UG=Hs.84928 nuclear transcription factor Y, beta /FL=gb:NM_006166.2 gb:BC005316.1 gb:BC005317.1 gb:L06145.1 AI804118 nuclear transcription factor Y, beta NFYB 4801 NM_006166 /// XM_005268908 /// XM_005268909 /// XM_005268910 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction 218128_at AU151875 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151875 /FEA=EST /DB_XREF=gi:11013396 /DB_XREF=est:AU151875 /CLONE=NT2RP2006282 /UG=Hs.84928 nuclear transcription factor Y, beta /FL=gb:NM_006166.2 gb:BC005316.1 gb:BC005317.1 gb:L06145.1 AU151875 nuclear transcription factor Y, beta NFYB 4801 NM_006166 /// XM_005268908 /// XM_005268909 /// XM_005268910 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction 218129_s_at NM_006166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006166.2 /DEF=Homo sapiens nuclear transcription factor Y, beta (NFYB), mRNA. /FEA=mRNA /GEN=NFYB /PROD=nuclear transcription factor Y, beta /DB_XREF=gi:11496976 /UG=Hs.84928 nuclear transcription factor Y, beta /FL=gb:NM_006166.2 gb:BC005316.1 gb:BC005317.1 gb:L06145.1 NM_006166 nuclear transcription factor Y, beta NFYB 4801 NM_006166 /// XM_005268908 /// XM_005268909 /// XM_005268910 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction 218130_at NM_024510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024510.1 /DEF=Homo sapiens hypothetical protein MGC4368 (MGC4368), mRNA. /FEA=mRNA /GEN=MGC4368 /PROD=hypothetical protein MGC4368 /DB_XREF=gi:13375647 /UG=Hs.9732 hypothetical protein MGC4368 /FL=gb:BC003595.1 gb:BC004171.1 gb:NM_024510.1 NM_024510 chromosome 17 open reading frame 62 C17orf62 79415 NM_001033046 /// NM_001100407 /// NM_001100408 /// NM_001193653 /// NM_001193654 /// NM_001193655 /// NM_001193657 /// NR_036514 /// NR_036516 /// NR_036517 /// NR_036518 /// NR_036519 /// XM_006722293 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218131_s_at NM_017660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017660.1 /DEF=Homo sapiens hypothetical protein FLJ20085 (FLJ20085), mRNA. /FEA=mRNA /GEN=FLJ20085 /PROD=hypothetical protein FLJ20085 /DB_XREF=gi:8923093 /UG=Hs.118964 hypothetical protein FLJ20085 /FL=gb:NM_017660.1 NM_017660 GATA zinc finger domain containing 2A GATAD2A 54815 NM_017660 /// XM_005259954 /// XM_005259956 /// XM_005259957 /// XM_005259958 /// XM_005259959 /// XM_005259960 /// XM_005259961 /// XM_005259962 /// XM_006722780 /// XM_006722781 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0021506 // anterior neuropore closure // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218132_s_at NM_024075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024075.1 /DEF=Homo sapiens LENG5 protein (LENG5), mRNA. /FEA=mRNA /GEN=LENG5 /PROD=LENG5 protein /DB_XREF=gi:13129061 /UG=Hs.15580 LENG5 protein /FL=gb:BC000944.2 gb:NM_024075.1 NM_024075 TSEN34 tRNA splicing endonuclease subunit TSEN34 79042 NM_001077446 /// NM_001282332 /// NM_001282333 /// NM_024075 /// XM_005259241 /// XM_005277087 /// XM_005277276 /// XM_005277318 /// XM_005278290 /// XM_006725878 /// XM_006725966 /// XM_006726065 /// XM_006726166 /// XM_006726203 0000379 // tRNA-type intron splice site recognition and cleavage // inferred from electronic annotation /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0000214 // tRNA-intron endonuclease complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0000213 // tRNA-intron endonuclease activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 218133_s_at NM_021824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021824.1 /DEF=Homo sapiens NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1 (NIF3L1), mRNA. /FEA=mRNA /GEN=NIF3L1 /PROD=NIF3 (Ngg1 interacting factor 3, S.pombehomolog)-like 1 /DB_XREF=gi:11141898 /UG=Hs.21943 NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1 /FL=gb:AF182416.1 gb:NM_021824.1 gb:AF060513.1 gb:AB038949.1 NM_021824 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) NIF3L1 60491 NM_001136039 /// NM_001142355 /// NM_001142356 /// NM_021824 /// XM_005246742 /// XM_006712676 0035998 // 7,8-dihydroneopterin 3'-triphosphate biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003934 // GTP cyclohydrolase I activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218134_s_at NM_018047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018047.1 /DEF=Homo sapiens hypothetical protein FLJ10290 (FLJ10290), mRNA. /FEA=mRNA /GEN=FLJ10290 /PROD=hypothetical protein FLJ10290 /DB_XREF=gi:8922327 /UG=Hs.25516 hypothetical protein FLJ10290 /FL=gb:AL136933.1 gb:BC003402.1 gb:NM_018047.1 NM_018047 RNA binding motif protein 22 RBM22 55696 NM_018047 /// XM_005268479 0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0033120 // positive regulation of RNA splicing // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay /// 0090316 // positive regulation of intracellular protein transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017069 // snRNA binding // inferred from direct assay /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 218135_at NM_016570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016570.1 /DEF=Homo sapiens CDA14 (LOC51290), mRNA. /FEA=mRNA /GEN=LOC51290 /PROD=CDA14 /DB_XREF=gi:7706104 /UG=Hs.26813 CDA14 /FL=gb:BC000887.1 gb:AF216751.1 gb:NM_016570.1 gb:AF183410.1 NM_016570 ERGIC and golgi 2 ERGIC2 51290 NM_016570 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 218136_s_at NM_018579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018579.1 /DEF=Homo sapiens mitochondrial solute carrier (LOC51312), mRNA. /FEA=mRNA /GEN=LOC51312 /PROD=hypothetical protein PRO1278 /DB_XREF=gi:8924027 /UG=Hs.300496 mitochondrial solute carrier /FL=gb:AF155660.1 gb:AF116630.1 gb:NM_018579.1 NM_018579 solute carrier family 25 (mitochondrial iron transporter), member 37 SLC25A37 51312 NM_016612 /// XM_005273526 /// XM_006716352 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048250 // mitochondrial iron ion transport // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation 218137_s_at NM_021940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021940.1 /DEF=Homo sapiens hypothetical protein FLJ13159 (FLJ13159), mRNA. /FEA=mRNA /GEN=FLJ13159 /PROD=hypothetical protein FLJ13159 /DB_XREF=gi:11345477 /UG=Hs.4273 hypothetical protein FLJ13159 /FL=gb:NM_021940.1 NM_021940 small ArfGAP 1 SMAP1 60682 NM_001044305 /// NM_001281439 /// NM_001281440 /// NM_021940 /// XM_005248760 /// XM_006715547 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218138_at NM_018848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018848.1 /DEF=Homo sapiens McKusick-Kaufman syndrome (MKKS), mRNA. /FEA=mRNA /GEN=MKKS /PROD=McKusick-Kaufman syndrome protein /DB_XREF=gi:9055271 /UG=Hs.46743 McKusick-Kaufman syndrome /FL=gb:AF275813.1 gb:AF221992.1 gb:AF221993.1 gb:NM_018848.1 NM_018848 McKusick-Kaufman syndrome MKKS 8195 NM_018848 /// NM_170784 /// NR_072977 0001947 // heart looping // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007507 // heart development // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from sequence or structural similarity /// 0008406 // gonad development // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014824 // artery smooth muscle contraction // inferred from electronic annotation /// 0021756 // striatum development // inferred from sequence or structural similarity /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0033210 // leptin-mediated signaling pathway // inferred from electronic annotation /// 0035058 // nonmotile primary cilium assembly // inferred from electronic annotation /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0038108 // negative regulation of appetite by leptin-mediated signaling pathway // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044321 // response to leptin // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051877 // pigment granule aggregation in cell center // inferred from sequence or structural similarity /// 0060027 // convergent extension involved in gastrulation // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060296 // regulation of cilium beat frequency involved in ciliary motility // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 218139_s_at NM_018229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018229.1 /DEF=Homo sapiens hypothetical protein FLJ10813 (FLJ10813), mRNA. /FEA=mRNA /GEN=FLJ10813 /PROD=hypothetical protein FLJ10813 /DB_XREF=gi:8922687 /UG=Hs.106210 hypothetical protein FLJ10813 /FL=gb:AL136685.1 gb:NM_018229.1 NM_018229 adaptor-related protein complex 5, mu 1 subunit AP5M1 55745 NM_018229 /// NR_026895 /// XM_006720196 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030119 // AP-type membrane coat adaptor complex // inferred from direct assay /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218140_x_at NM_021203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021203.1 /DEF=Homo sapiens APMCF1 protein (APMCF1), mRNA. /FEA=mRNA /GEN=APMCF1 /PROD=APMCF1 protein /DB_XREF=gi:10864014 /UG=Hs.12152 APMCF1 protein /FL=gb:NM_021203.1 gb:AF141882.1 NM_021203 signal recognition particle receptor, B subunit SRPRB 58477 NM_021203 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008199 // ferric iron binding // inferred from electronic annotation 218141_at NM_022066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022066.1 /DEF=Homo sapiens hypothetical protein FLJ12878 (FLJ12878), mRNA. /FEA=mRNA /GEN=FLJ12878 /PROD=hypothetical protein FLJ12878 /DB_XREF=gi:11545776 /UG=Hs.16130 hypothetical protein FLJ12878 /FL=gb:NM_022066.1 NM_022066 ubiquitin-conjugating enzyme E2O UBE2O 63893 NM_022066 /// XM_005257567 /// XM_005257568 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0070534 // protein K63-linked ubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218142_s_at NM_016302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016302.1 /DEF=Homo sapiens protein x 0001 (LOC51185), mRNA. /FEA=mRNA /GEN=LOC51185 /PROD=protein x 0001 /DB_XREF=gi:10047097 /UG=Hs.18925 protein x 0001 /FL=gb:NM_016302.1 gb:AF117230.1 NM_016302 cereblon CRBN 51185 NM_001173482 /// NM_016302 /// XM_005265202 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0032463 // negative regulation of protein homooligomerization // inferred from electronic annotation /// 0034766 // negative regulation of ion transmembrane transport // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0090073 // positive regulation of protein homodimerization activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218143_s_at NM_005697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005697.2 /DEF=Homo sapiens secretory carrier membrane protein 2 (SCAMP2), mRNA. /FEA=mRNA /GEN=SCAMP2 /PROD=secretory carrier membrane protein 2 /DB_XREF=gi:5730030 /UG=Hs.238030 secretory carrier membrane protein 2 /FL=gb:BC001376.1 gb:BC004385.1 gb:AF005038.2 gb:NM_005697.2 NM_005697 secretory carrier membrane protein 2 SCAMP2 10066 NM_005697 /// XM_006720369 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218144_s_at NM_022489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022489.1 /DEF=Homo sapiens hypothetical protein FLJ22056 (FLJ22056), mRNA. /FEA=mRNA /GEN=FLJ22056 /PROD=hypothetical protein FLJ22056 /DB_XREF=gi:11968044 /UG=Hs.24956 hypothetical protein FLJ22056 /FL=gb:NM_022489.1 NM_022489 inverted formin, FH2 and WH2 domain containing INF2 64423 NM_001031714 /// NM_022489 /// NM_032714 /// XM_005268004 /// XM_005268005 0008219 // cell death // inferred from electronic annotation /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from electronic annotation /// 0090140 // regulation of mitochondrial fission // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 218145_at NM_021158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021158.1 /DEF=Homo sapiens protein kinase domains containing protein similar to phosphoprotein C8FW (LOC57761), mRNA. /FEA=mRNA /GEN=LOC57761 /PROD=protein kinase domains containing proteinsimilar to phosphoprotein C8FW /DB_XREF=gi:11056039 /UG=Hs.26802 protein kinase domains containing protein similar to phosphoprotein C8FW /FL=gb:NM_021158.1 NM_021158 tribbles pseudokinase 3 TRIB3 57761 NM_021158 /// XM_005260773 /// XM_005260774 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010827 // regulation of glucose transport // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043405 // regulation of MAP kinase activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity 218146_at NM_018446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018446.1 /DEF=Homo sapiens AD-017 protein (LOC55830), mRNA. /FEA=mRNA /GEN=LOC55830 /PROD=AD-017 protein /DB_XREF=gi:8923854 /UG=Hs.283737 AD-017 protein /FL=gb:BC001418.1 gb:AF157318.1 gb:NM_018446.1 NM_018446 glycosyltransferase 8 domain containing 1 GLT8D1 55830 NM_001010983 /// NM_001278280 /// NM_001278281 /// NM_018446 /// NM_152932 /// XM_006713260 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 218147_s_at NM_018446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018446.1 /DEF=Homo sapiens AD-017 protein (LOC55830), mRNA. /FEA=mRNA /GEN=LOC55830 /PROD=AD-017 protein /DB_XREF=gi:8923854 /UG=Hs.283737 AD-017 protein /FL=gb:BC001418.1 gb:AF157318.1 gb:NM_018446.1 NM_018446 glycosyltransferase 8 domain containing 1 GLT8D1 55830 NM_001010983 /// NM_001278280 /// NM_001278281 /// NM_018446 /// NM_152932 /// XM_006713260 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 218148_at NM_025082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025082.1 /DEF=Homo sapiens hypothetical protein FLJ13111 (FLJ13111), mRNA. /FEA=mRNA /GEN=FLJ13111 /PROD=hypothetical protein FLJ13111 /DB_XREF=gi:13376635 /UG=Hs.288382 hypothetical protein FLJ13111 /FL=gb:NM_025082.1 NM_025082 centromere protein T CENPT 80152 NM_025082 /// XM_006721277 /// XM_006721278 /// XM_006721279 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218149_s_at NM_017606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017606.1 /DEF=Homo sapiens hypothetical protein DKFZp434K1210 (DKFZp434K1210), mRNA. /FEA=mRNA /GEN=DKFZp434K1210 /PROD=hypothetical protein DKFZp434K1210 /DB_XREF=gi:8922146 /UG=Hs.32352 hypothetical protein DKFZp434K1210 /FL=gb:NM_017606.1 NM_017606 zinc finger protein 395 ZNF395 55893 NM_018660 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218150_at NM_012097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012097.1 /DEF=Homo sapiens ADP-ribosylation factor-like 5 (ARL5), mRNA. /FEA=mRNA /GEN=ARL5 /PROD=ADP-ribosylation factor-like 5 /DB_XREF=gi:6912243 /UG=Hs.42500 ADP-ribosylation factor-like 5 /FL=gb:BC001254.1 gb:AF100740.1 gb:NM_012097.1 NM_012097 ADP-ribosylation factor-like 5A /// uncharacterized LOC101929356 ARL5A /// LOC101929356 26225 /// 101929356 NM_001037174 /// NM_012097 /// NM_177985 /// XR_241333 /// XR_249228 /// XR_251200 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218151_x_at NM_024531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024531.1 /DEF=Homo sapiens hypothetical protein FLJ11856 (FLJ11856), mRNA. /FEA=mRNA /GEN=FLJ11856 /PROD=hypothetical protein FLJ11856 /DB_XREF=gi:13375681 /UG=Hs.6459 hypothetical protein FLJ11856 /FL=gb:BC002917.1 gb:NM_024531.1 NM_024531 solute carrier family 52 (riboflavin transporter), member 2 SLC52A2 79581 NM_001253815 /// NM_001253816 /// NM_024531 /// NR_045600 /// XM_006716658 /// XM_006716659 /// XM_006716660 0006810 // transport // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0032218 // riboflavin transport // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0032217 // riboflavin transporter activity // inferred from direct assay 218152_at NM_018200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018200.1 /DEF=Homo sapiens high-mobility group 20A (HMG20A), mRNA. /FEA=mRNA /GEN=HMG20A /PROD=high-mobility group 20A /DB_XREF=gi:8922632 /UG=Hs.69594 high-mobility group 20A /FL=gb:AF146222.1 gb:NM_018200.1 NM_018200 high mobility group 20A HMG20A 10363 NM_018200 /// XM_005254123 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218153_at NM_024537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024537.1 /DEF=Homo sapiens hypothetical protein FLJ12118 (FLJ12118), mRNA. /FEA=mRNA /GEN=FLJ12118 /PROD=hypothetical protein FLJ12118 /DB_XREF=gi:13375694 /UG=Hs.7779 hypothetical protein FLJ12118 /FL=gb:NM_024537.1 NM_024537 cysteinyl-tRNA synthetase 2, mitochondrial (putative) CARS2 79587 NM_024537 /// XM_006719953 /// XR_243047 /// XR_243048 /// XR_243049 /// XR_243051 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006423 // cysteinyl-tRNA aminoacylation // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004817 // cysteine-tRNA ligase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218154_at NM_024736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024736.1 /DEF=Homo sapiens hypothetical protein FLJ12150 (FLJ12150), mRNA. /FEA=mRNA /GEN=FLJ12150 /PROD=hypothetical protein FLJ12150 /DB_XREF=gi:13376057 /UG=Hs.118983 hypothetical protein FLJ12150 /FL=gb:NM_024736.1 NM_024736 gasdermin D GSDMD 79792 NM_001166237 /// NM_024736 /// XR_428382 /// XR_428383 /// XR_428384 /// XR_430687 /// XR_430688 /// XR_430689 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation 218155_x_at AK026565 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026565.1 /DEF=Homo sapiens cDNA: FLJ22912 fis, clone KAT06132. /FEA=mRNA /DB_XREF=gi:10439447 /UG=Hs.204501 hypothetical protein FLJ10534 /FL=gb:NM_018128.1 AK026565 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) TSR1 55720 NM_018128 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity 0044822 // poly(A) RNA binding // inferred from direct assay 218156_s_at NM_018128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018128.1 /DEF=Homo sapiens hypothetical protein FLJ10534 (FLJ10534), mRNA. /FEA=mRNA /GEN=FLJ10534 /PROD=hypothetical protein FLJ10534 /DB_XREF=gi:8922495 /UG=Hs.204501 hypothetical protein FLJ10534 /FL=gb:NM_018128.1 NM_018128 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) TSR1 55720 NM_018128 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity 0044822 // poly(A) RNA binding // inferred from direct assay 218157_x_at NM_020239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020239.2 /DEF=Homo sapiens small protein effector 1 of Cdc42 (SPEC1), mRNA. /FEA=mRNA /GEN=SPEC1 /PROD=small protein effector 1 of Cdc42 /DB_XREF=gi:12965169 /UG=Hs.22065 small protein effector 1 of Cdc42 /FL=gb:AF187845.2 gb:NM_020239.2 NM_020239 CDC42 small effector 1 CDC42SE1 56882 NM_001038707 /// NM_020239 0006909 // phagocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005095 // GTPase inhibitor activity // traceable author statement 218158_s_at NM_012096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012096.1 /DEF=Homo sapiens adaptor protein containing pH domain, PTB domain and leucine zipper motif (APPL), mRNA. /FEA=mRNA /GEN=APPL /PROD=adaptor protein containing pH domain, PTB domainand leucine zipper motif /DB_XREF=gi:6912241 /UG=Hs.27413 adaptor protein containing pH domain, PTB domain and leucine zipper motif /FL=gb:AF169797.1 gb:NM_012096.1 NM_012096 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 APPL1 26060 NM_012096 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0046324 // regulation of glucose import // inferred from mutant phenotype /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred by curator /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction 218159_at NM_023935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023935.1 /DEF=Homo sapiens hypothetical protein MGC2592 (MGC2592), mRNA. /FEA=mRNA /GEN=MGC2592 /PROD=hypothetical protein MGC2592 /DB_XREF=gi:13027601 /UG=Hs.28393 hypothetical protein MGC2592 /FL=gb:BC000643.1 gb:NM_023935.1 NM_023935 DDRGK domain containing 1 DDRGK1 65992 NM_023935 0005783 // endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218160_at NM_014222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014222.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD, PGIV) (NDUFA8), mRNA. /FEA=mRNA /GEN=NDUFA8 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 8 (19kD, PGIV) /DB_XREF=gi:7657368 /UG=Hs.31547 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD, PGIV) /FL=gb:BC001016.1 gb:AF044953.1 gb:NM_014222.1 NM_014222 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa NDUFA8 4702 NM_014222 /// XM_005251998 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0032403 // protein complex binding // inferred from direct assay 218161_s_at NM_017882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017882.1 /DEF=Homo sapiens hypothetical protein FLJ20561 (FLJ20561), mRNA. /FEA=mRNA /GEN=FLJ20561 /PROD=hypothetical protein FLJ20561 /DB_XREF=gi:8923531 /UG=Hs.43654 hypothetical protein FLJ20561 /FL=gb:NM_017882.1 NM_017882 ceroid-lipofuscinosis, neuronal 6, late infantile, variant CLN6 54982 NM_017882 0001573 // ganglioside metabolic process // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030203 // glycosaminoglycan metabolic process // inferred from mutant phenotype /// 0031987 // locomotion involved in locomotory behavior // inferred from electronic annotation /// 0044265 // cellular macromolecule catabolic process // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 218162_at NM_020190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020190.1 /DEF=Homo sapiens HNOEL-iso protein (HNOEL-iso), mRNA. /FEA=mRNA /GEN=HNOEL-iso /PROD=HNOEL-iso protein /DB_XREF=gi:9910269 /UG=Hs.9315 HNOEL-iso protein /FL=gb:AF201945.1 gb:NM_020190.1 NM_020190 olfactomedin-like 3 OLFML3 56944 NM_001286352 /// NM_001286353 /// NM_020190 /// XM_006710778 0007275 // multicellular organismal development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218163_at NM_014060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014060.1 /DEF=Homo sapiens MCT-1 protein (MCT-1), mRNA. /FEA=mRNA /GEN=MCT-1 /PROD=MCT-1 protein /DB_XREF=gi:7662501 /UG=Hs.102696 MCT-1 protein /FL=gb:BC001013.1 gb:AB034206.1 gb:NM_014060.1 NM_014060 malignant T cell amplified sequence 1 MCTS1 28985 NM_001137554 /// NM_014060 0001731 // formation of translation preinitiation complex // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032790 // ribosome disassembly // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation 218164_at NM_022827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022827.1 /DEF=Homo sapiens hypothetical protein FLJ21347 (FLJ21347), mRNA. /FEA=mRNA /GEN=FLJ21347 /PROD=hypothetical protein FLJ21347 /DB_XREF=gi:12383067 /UG=Hs.103147 hypothetical protein FLJ21347 /FL=gb:NM_022827.1 NM_022827 spermatogenesis associated 20 SPATA20 64847 NM_001258372 /// NM_001258373 /// NM_022827 0006013 // mannose metabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004476 // mannose-6-phosphate isomerase activity // inferred from electronic annotation 218165_at NM_022756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022756.1 /DEF=Homo sapiens hypothetical protein FLJ11730 (FLJ11730), mRNA. /FEA=mRNA /GEN=FLJ11730 /PROD=hypothetical protein FLJ11730 /DB_XREF=gi:12232424 /UG=Hs.17118 hypothetical protein FLJ11730 /FL=gb:NM_022756.1 NM_022756 MYST/Esa1-associated factor 6 MEAF6 64769 NM_001270875 /// NM_001270876 /// NM_022756 /// NR_073090 /// NR_073091 /// NR_073092 /// XM_006710821 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0044154 // histone H3-K14 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218166_s_at NM_016578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016578.2 /DEF=Homo sapiens HBV pX associated protein-8 (LOC51773), mRNA. /FEA=mRNA /GEN=LOC51773 /PROD=HBV pX associated protein-8 /DB_XREF=gi:10835261 /UG=Hs.20509 HBV pX associated protein-8 /FL=gb:AF227948.2 gb:NM_016578.2 NM_016578 remodeling and spacing factor 1 RSF1 51773 NM_016578 /// XM_005274051 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050434 // positive regulation of viral transcription // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0031213 // RSF complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218167_at NM_016627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016627.1 /DEF=Homo sapiens hypothetical protein (LOC51321), mRNA. /FEA=mRNA /GEN=LOC51321 /PROD=hypothetical protein /DB_XREF=gi:7706167 /UG=Hs.268122 hypothetical protein /FL=gb:AF208856.1 gb:NM_016627.1 NM_016627 archaelysin family metallopeptidase 2 AMZ2 51321 NM_001033569 /// NM_001033570 /// NM_001033571 /// NM_001033572 /// NM_001033574 /// NM_001289054 /// NM_001289056 /// NM_016627 /// XM_005257432 /// XM_005257433 /// XM_005257435 /// XM_005257436 /// XM_005257437 /// XM_005257438 /// XM_006721940 0006508 // proteolysis // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218168_s_at NM_020247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020247.1 /DEF=Homo sapiens hypothetical protein, clone Telethon(Italy_B41)_Strait02270_FL142 (LOC56997), mRNA. /FEA=mRNA /GEN=LOC56997 /PROD=hypothetical protein, cloneTelethon(Italy_B41)_Strait02270_FL142 /DB_XREF=gi:9910387 /UG=Hs.273186 hypothetical protein, clone Telethon(Italy_B41)_Strait02270_FL142 /FL=gb:BC005171.1 gb:NM_020247.1 NM_020247 aarF domain containing kinase 3 ADCK3 56997 NM_020247 /// XM_005273201 /// XM_005273202 /// XM_005273203 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 218169_at NM_018052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018052.1 /DEF=Homo sapiens hypothetical protein FLJ10305 (FLJ10305), mRNA. /FEA=mRNA /GEN=FLJ10305 /PROD=hypothetical protein FLJ10305 /DB_XREF=gi:8922339 /UG=Hs.5894 hypothetical protein FLJ10305 /FL=gb:BC000536.1 gb:NM_018052.1 NM_018052 Vac14 homolog (S. cerevisiae) VAC14 55697 NM_018052 /// XM_005256038 /// XM_005256039 /// XM_005256040 /// XM_005256041 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043550 // regulation of lipid kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070772 // PAS complex // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from electronic annotation 218170_at NM_016048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016048.1 /DEF=Homo sapiens CGI-111 protein (LOC51015), mRNA. /FEA=mRNA /GEN=LOC51015 /PROD=CGI-111 protein /DB_XREF=gi:7705613 /UG=Hs.11085 CGI-111 protein /FL=gb:AF151869.1 gb:NM_016048.1 NM_016048 isochorismatase domain containing 1 ISOC1 51015 NM_016048 0008152 // metabolic process // inferred from electronic annotation 0005777 // peroxisome // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation 218171_at AF195514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF195514.1 /DEF=Homo sapiens VPS4-2 ATPase (VPS42) mRNA, complete cds. /FEA=mRNA /GEN=VPS42 /PROD=VPS4-2 ATPase /DB_XREF=gi:11225484 /UG=Hs.126550 suppressor of K+ transport defect 1 /FL=gb:AF195514.1 gb:AF038960.1 gb:NM_004869.1 AF195514 vacuolar protein sorting 4 homolog B (S. cerevisiae) VPS4B 9525 NM_004869 /// XM_006722582 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // inferred from direct assay /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032510 // endosome to lysosome transport via multivesicular body sorting pathway // inferred from mutant phenotype /// 0033993 // response to lipid // inferred from direct assay /// 0050792 // regulation of viral process // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1902188 // positive regulation of viral release from host cell // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005774 // vacuolar membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // non-traceable author statement 218172_s_at NM_018630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018630.1 /DEF=Homo sapiens hypothetical protein PRO2577 (PRO2577), mRNA. /FEA=mRNA /GEN=PRO2577 /PROD=hypothetical protein PRO2577 /DB_XREF=gi:8924181 /UG=Hs.241576 hypothetical protein PRO2577 /FL=gb:AF116708.1 gb:NM_018630.1 NM_018630 derlin 1 DERL1 79139 NM_001134671 /// NM_024295 /// XM_006716657 0006810 // transport // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype /// 0034620 // cellular response to unfolded protein // inferred from electronic annotation /// 0045184 // establishment of protein localization // traceable author statement 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // inferred from direct assay 218173_s_at NM_017778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017778.2 /DEF=Homo sapiens Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant short, mRNA. /FEA=mRNA /GEN=WHSC1L1 /PROD=WHSC1L1 protein isoform short /DB_XREF=gi:13699812 /UG=Hs.27721 Wolf-Hirschhorn syndrome candidate 1-like 1 /FL=gb:AF332468.1 gb:NM_017778.2 NM_017778 Wolf-Hirschhorn syndrome candidate 1-like 1 WHSC1L1 54904 NM_017778 /// NM_023034 /// XM_005273547 /// XM_005273548 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0030154 // cell differentiation // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218174_s_at NM_025125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025125.1 /DEF=Homo sapiens hypothetical protein FLJ13263 (FLJ13263), mRNA. /FEA=mRNA /GEN=FLJ13263 /PROD=hypothetical protein FLJ13263 /DB_XREF=gi:13376702 /UG=Hs.288768 hypothetical protein FLJ13263 /FL=gb:NM_025125.1 NM_025125 transmembrane protein 254 TMEM254 80195 NM_001270367 /// NM_001270368 /// NM_001270369 /// NM_001270370 /// NM_001270371 /// NM_001270372 /// NM_001270373 /// NM_001270374 /// NM_025125 /// NR_072984 /// NR_072985 /// NR_072986 /// NR_072987 /// XM_006717978 /// XM_006717979 /// XM_006717980 /// XM_006717981 /// XM_006717982 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218175_at NM_025140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025140.1 /DEF=Homo sapiens hypothetical protein FLJ22471 (FLJ22471), mRNA. /FEA=mRNA /GEN=FLJ22471 /PROD=hypothetical protein FLJ22471 /DB_XREF=gi:13376724 /UG=Hs.288909 hypothetical protein FLJ22471 /FL=gb:NM_025140.1 NM_025140 coiled-coil domain containing 92 CCDC92 80212 NM_025140 /// XM_005253624 /// XM_005253625 /// XM_006719611 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218176_at NM_022149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022149.1 /DEF=Homo sapiens MAGEF1 protein (MAGEF1), mRNA. /FEA=mRNA /GEN=MAGEF1 /PROD=MAGEF1 protein /DB_XREF=gi:11545891 /UG=Hs.306123 MAGEF1 protein /FL=gb:AF295378.1 gb:NM_022149.1 NM_022149 melanoma antigen family F, 1 MAGEF1 64110 NM_022149 0070062 // extracellular vesicular exosome // inferred from direct assay 218177_at AA293502 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA293502 /FEA=EST /DB_XREF=gi:1941036 /DB_XREF=est:zt53h06.r1 /CLONE=IMAGE:726107 /UG=Hs.42733 CHMP1.5 protein /FL=gb:AF281064.1 gb:NM_020412.1 AA293502 charged multivesicular body protein 1B CHMP1B 57132 NM_020412 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 218178_s_at NM_020412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020412.1 /DEF=Homo sapiens CHMP1.5 protein (CHMP1.5), mRNA. /FEA=mRNA /GEN=CHMP1.5 /PROD=CHMP1.5 protein /DB_XREF=gi:9966900 /UG=Hs.42733 CHMP1.5 protein /FL=gb:AF281064.1 gb:NM_020412.1 NM_020412 charged multivesicular body protein 1B CHMP1B 57132 NM_020412 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 218179_s_at NM_021942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021942.1 /DEF=Homo sapiens hypothetical protein FLJ12716 (FLJ12716), mRNA. /FEA=mRNA /GEN=FLJ12716 /PROD=hypothetical protein FLJ12716 /DB_XREF=gi:11345481 /UG=Hs.5354 hypothetical protein FLJ12716 /FL=gb:NM_021942.1 gb:AL136752.1 NM_021942 trafficking protein particle complex 11 TRAPPC11 60684 NM_021942 /// NM_199053 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation 218180_s_at NM_022772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022772.1 /DEF=Homo sapiens hypothetical protein FLJ21935 (FLJ21935), mRNA. /FEA=mRNA /GEN=FLJ21935 /PROD=hypothetical protein FLJ21935 /DB_XREF=gi:12232452 /UG=Hs.55016 hypothetical protein FLJ21935 /FL=gb:NM_022772.1 gb:BC002474.1 NM_022772 EPS8-like 2 EPS8L2 64787 NM_022772 /// XM_006718273 /// XM_006718274 /// XM_006718275 /// XM_006718276 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay 218181_s_at NM_017792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017792.1 /DEF=Homo sapiens hypothetical protein FLJ20373 (FLJ20373), mRNA. /FEA=mRNA /GEN=FLJ20373 /PROD=hypothetical protein FLJ20373 /DB_XREF=gi:8923351 /UG=Hs.6631 hypothetical protein FLJ20373 /FL=gb:NM_017792.1 NM_017792 mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4 9448 NM_001242559 /// NM_001242560 /// NM_004834 /// NM_145686 /// NM_145687 /// XM_005264044 /// XM_005264045 /// XM_005264046 /// XM_005264047 /// XM_005264048 /// XM_005264049 /// XM_005264050 /// XM_005264052 /// XM_005264053 /// XM_005264054 /// XM_005264055 /// XM_005264056 /// XM_005264057 /// XM_005264058 /// XM_005264059 /// XM_005264060 /// XM_005264061 /// XM_005264062 /// XM_005264063 /// XM_005264064 /// XM_005264065 /// XM_005264066 /// XM_005264068 /// XM_005264069 /// XM_005264071 /// XM_006712864 /// XM_006712865 /// XM_006712866 /// XM_006712867 /// XM_006712868 /// XM_006712869 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 218182_s_at NM_021101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021101.1 /DEF=Homo sapiens claudin 1 (CLDN1), mRNA. /FEA=mRNA /GEN=CLDN1 /PROD=claudin 1 /DB_XREF=gi:10863886 /UG=Hs.7327 claudin 1 /FL=gb:NM_021101.1 gb:AF101051.1 gb:AF115546.1 gb:AF134160.1 NM_021101 claudin 1 CLDN1 9076 NM_021101 0007155 // cell adhesion // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0061436 // establishment of skin barrier // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity 218183_at NM_013399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013399.1 /DEF=Homo sapiens chromosome 16 open reading frame 5 (C16orf5), mRNA. /FEA=mRNA /GEN=C16orf5 /PROD=chromosome 16 open reading frame 5 /DB_XREF=gi:7019336 /UG=Hs.7765 chromosome 16 open reading frame 5 /FL=gb:AL136698.1 gb:BC002882.1 gb:AF131218.1 gb:NM_013399.1 NM_013399 cell death-inducing p53 target 1 CDIP1 29965 NM_001199054 /// NM_001199055 /// NM_001199056 /// NM_013399 0006915 // apoptotic process // inferred from genetic interaction /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from genetic interaction /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 218184_at NM_020245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020245.2 /DEF=Homo sapiens tubby super-family protein (TUSP), mRNA. /FEA=mRNA /GEN=TUSP /PROD=tubby super-family protein /DB_XREF=gi:12383052 /UG=Hs.102237 tubby super-family protein /FL=gb:AF219946.2 gb:NM_020245.2 NM_020245 tubby like protein 4 TULP4 56995 NM_001007466 /// NM_020245 /// XM_005267057 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 218185_s_at NM_018120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018120.1 /DEF=Homo sapiens hypothetical protein FLJ10511 (FLJ10511), mRNA. /FEA=mRNA /GEN=FLJ10511 /PROD=hypothetical protein FLJ10511 /DB_XREF=gi:8922478 /UG=Hs.106768 hypothetical protein FLJ10511 /FL=gb:NM_018120.1 NM_018120 armadillo repeat containing 1 ARMC1 55156 NM_001286702 /// NM_018120 /// XM_005251264 /// XM_006716458 0030001 // metal ion transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218186_at NM_020387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020387.1 /DEF=Homo sapiens CATX-8 protein (CATX-8), mRNA. /FEA=mRNA /GEN=CATX-8 /PROD=CATX-8 protein /DB_XREF=gi:9966860 /UG=Hs.150826 CATX-8 protein /FL=gb:AF083124.1 gb:NM_020387.1 NM_020387 RAB25, member RAS oncogene family RAB25 57111 NM_020387 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031268 // pseudopodium organization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from direct assay /// 0031260 // pseudopodium membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 218187_s_at NM_023080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023080.1 /DEF=Homo sapiens hypothetical protein FLJ20989 (FLJ20989), mRNA. /FEA=mRNA /GEN=FLJ20989 /PROD=hypothetical protein FLJ20989 /DB_XREF=gi:12751496 /UG=Hs.169615 hypothetical protein FLJ20989 /FL=gb:NM_023080.1 NM_023080 chromosome 8 open reading frame 33 C8orf33 65265 NM_023080 218188_s_at NM_012458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012458.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 13 (yeast) homolog B (TIMM13B), mRNA. /FEA=mRNA /GEN=TIMM13B /PROD=translocase of inner mitochondrial membrane 13(yeast) homolog B /DB_XREF=gi:11024699 /UG=Hs.23410 translocase of inner mitochondrial membrane 13 (yeast) homolog B /FL=gb:NM_012458.1 gb:AF144700.1 gb:AF152352.1 NM_012458 translocase of inner mitochondrial membrane 13 homolog (yeast) TIMM13 26517 NM_012458 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072321 // chaperone-mediated protein transport // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042719 // mitochondrial intermembrane space protein transporter complex // traceable author statement 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218189_s_at NM_018946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018946.2 /DEF=Homo sapiens N-acetylneuraminic acid phosphate synthase; sialic acid synthase (SAS), mRNA. /FEA=mRNA /GEN=SAS /PROD=N-acetylneuraminic acid phosphate synthase /DB_XREF=gi:12056472 /UG=Hs.274424 N-acetylneuraminic acid phosphate synthase; sialic acid synthase /FL=gb:NM_018946.2 gb:BC000008.1 gb:AF257466.1 NM_018946 N-acetylneuraminic acid synthase NANS 54187 NM_018946 0009103 // lipopolysaccharide biosynthetic process // non-traceable author statement /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008781 // N-acylneuraminate cytidylyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047444 // N-acylneuraminate-9-phosphate synthase activity // inferred from electronic annotation /// 0050462 // N-acetylneuraminate synthase activity // inferred from electronic annotation 218190_s_at NM_013387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013387.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase complex (7.2 kD) (HSPC051), mRNA. /FEA=mRNA /GEN=HSPC051 /PROD=ubiquinol-cytochrome c reductase complex (7.2kD) /DB_XREF=gi:9994180 /UG=Hs.284292 ubiquinol-cytochrome c reductase complex (7.2 kD) /FL=gb:AB028598.1 gb:BC005402.1 gb:AF112217.1 gb:AF161536.1 gb:AF161468.1 gb:NM_013387.1 NM_013387 ubiquinol-cytochrome c reductase, complex III subunit X UQCR10 29796 NM_001003684 /// NM_013387 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // non-traceable author statement 218191_s_at NM_018368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018368.1 /DEF=Homo sapiens hypothetical protein FLJ11240 (FLJ11240), mRNA. /FEA=mRNA /GEN=FLJ11240 /PROD=hypothetical protein FLJ11240 /DB_XREF=gi:8922955 /UG=Hs.301308 hypothetical protein FLJ11240 /FL=gb:AF113224.1 gb:AF211480.1 gb:NM_018368.1 NM_018368 LMBR1 domain containing 1 LMBRD1 55788 NM_018368 /// XM_006715511 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0031419 // cobalamin binding // inferred from electronic annotation 218192_at NM_016291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016291.1 /DEF=Homo sapiens mammalian inositol hexakisphosphate kinase 2 (IP6K2), mRNA. /FEA=mRNA /GEN=IP6K2 /PROD=mammalian inositol hexakisphosphate kinase 2 /DB_XREF=gi:7705552 /UG=Hs.323432 mammalian inositol hexakisphosphate kinase 2 /FL=gb:AF177145.1 gb:NM_016291.1 NM_016291 inositol hexakisphosphate kinase 2 IP6K2 51447 NM_001005909 /// NM_001005910 /// NM_001005911 /// NM_001005912 /// NM_001005913 /// NM_001146178 /// NM_001146179 /// NM_001190316 /// NM_001190317 /// NM_016291 /// NR_027437 /// NR_027438 /// XM_006713199 /// XM_006713200 /// XM_006713201 /// XM_006713202 0006817 // phosphate ion transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation 218193_s_at NM_016072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016072.1 /DEF=Homo sapiens CGI-141 protein (LOC51026), mRNA. /FEA=mRNA /GEN=LOC51026 /PROD=CGI-141 protein /DB_XREF=gi:7705635 /UG=Hs.62275 CGI-141 protein /FL=gb:AF151899.1 gb:AL136571.1 gb:NM_016072.1 NM_016072 golgi transport 1B GOLT1B 51026 NM_016072 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype 218194_at NM_015523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015523.1 /DEF=Homo sapiens small fragment nuclease (DKFZP566E144), mRNA. /FEA=mRNA /GEN=DKFZP566E144 /PROD=small fragment nuclease /DB_XREF=gi:7661645 /UG=Hs.7527 small fragment nuclease /FL=gb:AF151872.1 gb:AL110239.1 gb:NM_015523.1 NM_015523 RNA exonuclease 2 REXO2 25996 NM_015523 0006139 // nucleobase-containing compound metabolic process // inferred from direct assay /// 0009117 // nucleotide metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 218195_at NM_024573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024573.1 /DEF=Homo sapiens hypothetical protein FLJ12910 (FLJ12910), mRNA. /FEA=mRNA /GEN=FLJ12910 /PROD=hypothetical protein FLJ12910 /DB_XREF=gi:13375745 /UG=Hs.15929 hypothetical protein FLJ12910 /FL=gb:NM_024573.1 NM_024573 chromosome 6 open reading frame 211 C6orf211 79624 NM_001286562 /// NM_024573 218196_at NM_014028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014028.1 /DEF=Homo sapiens HSPC019 protein (HSPC019), mRNA. /FEA=mRNA /GEN=HSPC019 /PROD=HSPC019 protein /DB_XREF=gi:7661737 /UG=Hs.163724 HSPC019 protein /FL=gb:AF077205.1 gb:NM_014028.1 NM_014028 osteopetrosis associated transmembrane protein 1 OSTM1 28962 NM_014028 /// XM_006715464 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218197_s_at NM_018002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018002.1 /DEF=Homo sapiens oxidation resistance 1 (OXR1), mRNA. /FEA=mRNA /GEN=OXR1 /PROD=oxidation resistance 1 /DB_XREF=gi:8922240 /UG=Hs.169111 oxidation resistance 1 /FL=gb:NM_018002.1 NM_018002 oxidation resistance 1 OXR1 55074 NM_001198532 /// NM_001198533 /// NM_001198534 /// NM_001198535 /// NM_018002 /// NM_181354 /// XM_005250993 /// XM_005250994 /// XM_005250995 /// XM_005250996 /// XM_006716594 /// XM_006716595 /// XM_006716596 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // non-traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0016998 // cell wall macromolecule catabolic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071447 // cellular response to hydroperoxide // inferred from electronic annotation 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 218198_at NM_018180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018180.1 /DEF=Homo sapiens hypothetical protein FLJ10889 (FLJ10889), mRNA. /FEA=mRNA /GEN=FLJ10889 /PROD=hypothetical protein FLJ10694 /DB_XREF=gi:9506626 /UG=Hs.171835 hypothetical protein FLJ10889 /FL=gb:BC002473.1 gb:NM_018180.1 NM_018180 DEAH (Asp-Glu-Ala-His) box polypeptide 32 DHX32 55760 NM_018180 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218199_s_at NM_022917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022917.1 /DEF=Homo sapiens hypothetical protein FLJ21959 (FLJ21959), mRNA. /FEA=mRNA /GEN=FLJ21959 /PROD=hypothetical protein FLJ21959 /DB_XREF=gi:12597664 /UG=Hs.183253 hypothetical protein FLJ21959 /FL=gb:NM_022917.1 NM_022917 nucleolar protein 6 (RNA-associated) NOL6 65083 NM_022917 /// NM_130793 /// NM_139235 0006364 // rRNA processing // inferred from sequence or structural similarity 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay 0003723 // RNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 218200_s_at NM_004546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004546.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD, AGGG) (NDUFB2), mRNA. /FEA=mRNA /GEN=NDUFB2 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 2 (8kD, AGGG) /DB_XREF=gi:4758777 /UG=Hs.198272 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD, AGGG) /FL=gb:BC001168.1 gb:AF050639.1 gb:NM_004546.1 gb:AF067166.1 NM_004546 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa NDUFB2 4708 NM_004546 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 218201_at NM_004546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004546.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD, AGGG) (NDUFB2), mRNA. /FEA=mRNA /GEN=NDUFB2 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 2 (8kD, AGGG) /DB_XREF=gi:4758777 /UG=Hs.198272 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD, AGGG) /FL=gb:BC001168.1 gb:AF050639.1 gb:NM_004546.1 gb:AF067166.1 NM_004546 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa NDUFB2 4708 NM_004546 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 218202_x_at NM_022915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022915.1 /DEF=Homo sapiens hypothetical protein FLJ12701 (FLJ12701), mRNA. /FEA=mRNA /GEN=FLJ12701 /PROD=hypothetical protein FLJ12701 /DB_XREF=gi:12597660 /UG=Hs.203559 hypothetical protein FLJ12701 /FL=gb:NM_022915.1 NM_022915 mitochondrial ribosomal protein L44 MRPL44 65080 NM_022915 0006396 // RNA processing // inferred from electronic annotation /// 0070125 // mitochondrial translational elongation // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218203_at NM_013338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013338.2 /DEF=Homo sapiens Alg5, S. cerevisiae, homolog of (ALG5), mRNA. /FEA=mRNA /GEN=ALG5 /PROD=dolichyl phosphate glucosyltransferase /DB_XREF=gi:9665250 /UG=Hs.227933 Alg5, S. cerevisiae, homolog of /FL=gb:AF102850.1 gb:AF161498.1 gb:NM_013338.2 gb:AF183413.1 NM_013338 ALG5, dolichyl-phosphate beta-glucosyltransferase ALG5 29880 NM_001142364 /// NM_013338 /// XM_005266362 0006486 // protein glycosylation // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004576 // oligosaccharyl transferase activity // traceable author statement /// 0004581 // dolichyl-phosphate beta-glucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 218204_s_at NM_024513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024513.1 /DEF=Homo sapiens FYVE and coiled-coil domain containing 1 (FYCO1), mRNA. /FEA=mRNA /GEN=FYCO1 /PROD=FYVE and coiled-coil domain containing 1 /DB_XREF=gi:13470091 /UG=Hs.257267 FYVE and coiled-coil domain containing 1 /FL=gb:NM_024513.1 NM_024513 FYVE and coiled-coil domain containing 1 FYCO1 79443 NM_024513 /// XM_005265484 /// XM_006713333 /// XM_006713334 /// XM_006713335 /// XR_245157 0006810 // transport // inferred from electronic annotation /// 0072383 // plus-end-directed vesicle transport along microtubule // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218205_s_at NM_017572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017572.1 /DEF=Homo sapiens G protein-coupled receptor kinase 7 (GPRK7), mRNA. /FEA=mRNA /GEN=GPRK7 /PROD=G protein-coupled receptor kinase 7 /DB_XREF=gi:9994196 /UG=Hs.261828 G protein-coupled receptor kinase 7 /FL=gb:AF237776.1 gb:AF125532.1 gb:NM_017572.1 NM_017572 MAP kinase interacting serine/threonine kinase 2 MKNK2 2872 NM_017572 /// NM_199054 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218206_x_at NM_016558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016558.1 /DEF=Homo sapiens SCAN domain-containing 1 (SCAND1), mRNA. /FEA=mRNA /GEN=SCAND1 /PROD=SCAN domain-containing 1 /DB_XREF=gi:7706088 /UG=Hs.274411 SCAN domain-containing 1 /FL=gb:BC000785.1 gb:AF204271.1 gb:NM_016558.1 NM_016558 SCAN domain containing 1 SCAND1 51282 NM_016558 /// NM_033630 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // non-traceable author statement /// 0030851 // granulocyte differentiation // non-traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // not recorded /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity 218207_s_at NM_015894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015894.1 /DEF=Homo sapiens SCG10-like-protein (SCLIP), mRNA. /FEA=mRNA /GEN=SCLIP /PROD=SCG10-like-protein /DB_XREF=gi:7706694 /UG=Hs.285753 SCG10-like-protein /FL=gb:NM_015894.1 NM_015894 stathmin-like 3 STMN3 50861 NM_001276310 /// NM_015894 /// NR_075070 0007399 // nervous system development // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from sequence or structural similarity /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from sequence or structural similarity 218208_at NM_025078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025078.1 /DEF=Homo sapiens hypothetical protein FLJ22378 (FLJ22378), mRNA. /FEA=mRNA /GEN=FLJ22378 /PROD=hypothetical protein FLJ22378 /DB_XREF=gi:13376629 /UG=Hs.288284 hypothetical protein FLJ22378 /FL=gb:NM_025078.1 NM_025078 PQ loop repeat containing 1 PQLC1 80148 NM_001146343 /// NM_001146345 /// NM_025078 /// XM_005266769 /// XM_005266770 /// XM_006722549 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218209_s_at NM_018170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018170.1 /DEF=Homo sapiens hypothetical protein FLJ10656 (FLJ10656), mRNA. /FEA=mRNA /GEN=FLJ10656 /PROD=hypothetical protein FLJ10656 /DB_XREF=gi:8922574 /UG=Hs.300906 hypothetical protein FLJ10656 /FL=gb:NM_018170.1 NM_018170 regulation of nuclear pre-mRNA domain containing 1A RPRD1A 55197 NM_018170 /// XM_005258293 /// XM_005258294 0070940 // dephosphorylation of RNA polymerase II C-terminal domain // inferred from mutant phenotype 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay 218210_at NM_024619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024619.1 /DEF=Homo sapiens hypothetical protein FLJ12171 (FLJ12171), mRNA. /FEA=mRNA /GEN=FLJ12171 /PROD=hypothetical protein FLJ12171 /DB_XREF=gi:13375839 /UG=Hs.31431 hypothetical protein FLJ12171 /FL=gb:AL136631.1 gb:NM_024619.1 NM_024619 fructosamine 3 kinase related protein FN3KRP 79672 NM_024619 /// NR_046408 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 218211_s_at NM_024101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024101.1 /DEF=Homo sapiens hypothetical protein MGC2771 (MGC2771), mRNA. /FEA=mRNA /GEN=MGC2771 /PROD=hypothetical protein MGC2771 /DB_XREF=gi:13129107 /UG=Hs.321130 hypothetical protein MGC2771 /FL=gb:BC001653.1 gb:NM_024101.1 NM_024101 melanophilin MLPH 79083 NM_001042467 /// NM_001281473 /// NM_001281474 /// NM_024101 /// NR_104019 /// XM_006712737 /// XM_006712738 /// XM_006712739 /// XM_006712740 /// XM_006712741 /// XM_006712742 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from electronic annotation 218212_s_at NM_004531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004531.1 /DEF=Homo sapiens molybdenum cofactor synthesis 2 (MOCS2), mRNA. /FEA=mRNA /GEN=MOCS2 /PROD=molybdenum cofactor synthesis 2 /DB_XREF=gi:4758731 /UG=Hs.70565 molybdenum cofactor synthesis 2 /FL=gb:NM_004531.1 gb:AF155659.1 NM_004531 molybdenum cofactor synthesis 2 MOCS2 4338 NM_004531 /// NM_176806 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from direct assay /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from mutant phenotype /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019008 // molybdopterin synthase complex // inferred from physical interaction /// 0019008 // molybdopterin synthase complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030366 // molybdopterin synthase activity // inferred from direct assay /// 0030366 // molybdopterin synthase activity // traceable author statement /// 0042802 // identical protein binding // inferred from electronic annotation 218213_s_at NM_014206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014206.1 /DEF=Homo sapiens chromosome 11 open reading frame 10 (C11orf10), mRNA. /FEA=mRNA /GEN=C11orf10 /PROD=chromosome 11 open reading frame 10 /DB_XREF=gi:7656933 /UG=Hs.90918 chromosome 11 open reading frame 10 /FL=gb:BC002750.1 gb:AF070661.1 gb:AF086763.1 gb:NM_014206.1 NM_014206 transmembrane protein 258 TMEM258 746 NM_014206 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 218214_at NM_021934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021934.1 /DEF=Homo sapiens hypothetical protein FLJ11773 (FLJ11773), mRNA. /FEA=mRNA /GEN=FLJ11773 /PROD=hypothetical protein FLJ11773 /DB_XREF=gi:11345473 /UG=Hs.9911 hypothetical protein FLJ11773 /FL=gb:NM_021934.1 gb:BC005151.1 NM_021934 autophagy related 101 ATG101 60673 NM_001098673 /// NM_021934 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218215_s_at NM_007121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007121.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), mRNA. /FEA=mRNA /GEN=NR1H2 /PROD=nuclear receptor subfamily 1, group H, member 2 /DB_XREF=gi:11321629 /UG=Hs.100221 nuclear receptor subfamily 1, group H, member 2 /FL=gb:NM_007121.1 gb:U07132.1 NM_007121 nuclear receptor subfamily 1, group H, member 2 NR1H2 7376 NM_001256647 /// NM_007121 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from mutant phenotype /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010884 // positive regulation of lipid storage // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // inferred from mutant phenotype /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // non-traceable author statement /// 0090108 // positive regulation of high-density lipoprotein particle assembly // inferred from electronic annotation /// 0090187 // positive regulation of pancreatic juice secretion // inferred from electronic annotation /// 0090340 // positive regulation of secretion of lysosomal enzymes // inferred from electronic annotation /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001133 // sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0034191 // apolipoprotein A-I receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 218216_x_at NM_016638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016638.1 /DEF=Homo sapiens SRp25 nuclear protein (LOC51329), mRNA. /FEA=mRNA /GEN=LOC51329 /PROD=SRp25 nuclear protein /DB_XREF=gi:7706183 /UG=Hs.103561 SRp25 nuclear protein /FL=gb:BC001958.1 gb:AB035384.1 gb:NM_016638.1 NM_016638 ADP-ribosylation factor-like 6 interacting protein 4 ARL6IP4 51329 NM_001002251 /// NM_001002252 /// NM_001278378 /// NM_001278379 /// NM_001278380 /// NM_016638 /// NM_018694 /// NR_103512 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218217_at NM_021626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021626.1 /DEF=Homo sapiens serine carboxypeptidase 1 precursor protein (HSCP1), mRNA. /FEA=mRNA /GEN=HSCP1 /PROD=serine carboxypeptidase 1 precursor protein /DB_XREF=gi:11055991 /UG=Hs.106747 serine carboxypeptidase 1 precursor protein /FL=gb:AF282618.1 gb:NM_021626.1 gb:AF113214.1 gb:AF265441.1 NM_021626 serine carboxypeptidase 1 SCPEP1 59342 NM_021626 /// XM_005257557 0006508 // proteolysis // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218218_at NM_018171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018171.1 /DEF=Homo sapiens hypothetical protein FLJ10659 (FLJ10659), mRNA. /FEA=mRNA /GEN=FLJ10659 /PROD=hypothetical protein FLJ10659 /DB_XREF=gi:8922576 /UG=Hs.107882 hypothetical protein FLJ10659 /FL=gb:NM_018171.1 NM_018171 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 APPL2 55198 NM_001251904 /// NM_001251905 /// NM_018171 /// XM_005269001 /// XM_006719472 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred by curator /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 218219_s_at NM_018697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018697.1 /DEF=Homo sapiens TASP for testis-specific adriamycin sensitivity protein (LOC55915), mRNA. /FEA=mRNA /GEN=LOC55915 /PROD=TASP for testis-specific adriamycin sensitivityprotein /DB_XREF=gi:8923910 /UG=Hs.134342 TASP for testis-specific adriamycin sensitivity protein /FL=gb:AB035966.1 gb:NM_018697.1 NM_018697 LanC lantibiotic synthetase component C-like 2 (bacterial) LANCL2 55915 NM_018697 0008152 // metabolic process // inferred from electronic annotation /// 0009789 // positive regulation of abscisic acid-activated signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0005525 // GTP binding // non-traceable author statement /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay 218220_at NM_021640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021640.1 /DEF=Homo sapiens MYG1 protein (MYG1), mRNA. /FEA=mRNA /GEN=MYG1 /PROD=MYG1 protein /DB_XREF=gi:11056017 /UG=Hs.15760 MYG1 protein /FL=gb:AF289485.1 gb:NM_021640.1 NM_021640 chromosome 12 open reading frame 10 C12orf10 60314 NM_021640 0035641 // locomotory exploration behavior // inferred from electronic annotation /// 0043473 // pigmentation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 218221_at AL042842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL042842 /FEA=EST /DB_XREF=gi:5935598 /DB_XREF=est:DKFZp434G2322_s1 /CLONE=DKFZp434G2322 /UG=Hs.166172 aryl hydrocarbon receptor nuclear translocator /FL=gb:M69238.1 gb:NM_001668.1 AL042842 aryl hydrocarbon receptor nuclear translocator ARNT 405 NM_001197325 /// NM_001286035 /// NM_001286036 /// NM_001668 /// NM_178426 /// NM_178427 /// XM_005245151 /// XM_005245153 /// XM_005245154 /// XM_005245157 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045821 // positive regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004874 // aryl hydrocarbon receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017162 // aryl hydrocarbon receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 218222_x_at NM_001668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001668.1 /DEF=Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT), mRNA. /FEA=mRNA /GEN=ARNT /PROD=aryl hydrocarbon receptor nuclear translocator /DB_XREF=gi:4502230 /UG=Hs.166172 aryl hydrocarbon receptor nuclear translocator /FL=gb:M69238.1 gb:NM_001668.1 NM_001668 aryl hydrocarbon receptor nuclear translocator ARNT 405 NM_001197325 /// NM_001286035 /// NM_001286036 /// NM_001668 /// NM_178426 /// NM_178427 /// XM_005245151 /// XM_005245153 /// XM_005245154 /// XM_005245157 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045821 // positive regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004874 // aryl hydrocarbon receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017162 // aryl hydrocarbon receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 218223_s_at NM_016274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016274.1 /DEF=Homo sapiens CK2 interacting protein 1; HQ0024c protein (LOC51177), mRNA. /FEA=mRNA /GEN=LOC51177 /PROD=CK2 interacting protein 1; HQ0024c protein /DB_XREF=gi:7705918 /UG=Hs.173380 CK2 interacting protein 1; HQ0024c protein /FL=gb:AF291105.1 gb:AF073836.1 gb:NM_016274.1 gb:AF168676.1 NM_016274 pleckstrin homology domain containing, family O member 1 PLEKHO1 51177 NM_016274 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 218224_at NM_006029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006029.2 /DEF=Homo sapiens paraneoplastic antigen MA1 (PNMA1), mRNA. /FEA=mRNA /GEN=PNMA1 /PROD=paraneoplastic antigen MA1 /DB_XREF=gi:11141858 /UG=Hs.194709 paraneoplastic antigen MA1 /FL=gb:AF037364.2 gb:NM_006029.2 NM_006029 paraneoplastic Ma antigen 1 PNMA1 9240 NM_006029 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0006915 // apoptotic process // non-traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218225_at NM_016581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016581.1 /DEF=Homo sapiens ECSIT (LOC51295), mRNA. /FEA=mRNA /GEN=LOC51295 /PROD=ECSIT /DB_XREF=gi:7706114 /UG=Hs.22199 ECSIT /FL=gb:BC000193.1 gb:BC005119.1 gb:AF243044.1 gb:NM_016581.1 NM_016581 ECSIT signalling integrator ECSIT 51295 NM_001142464 /// NM_001142465 /// NM_001243204 /// NM_016581 0001707 // mesoderm formation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051341 // regulation of oxidoreductase activity // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from direct assay 218226_s_at NM_004547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004547.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4 (15kD, B15) (NDUFB4), mRNA. /FEA=mRNA /GEN=NDUFB4 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 4 (15kD, B15) /DB_XREF=gi:6041668 /UG=Hs.227750 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4 (15kD, B15) /FL=gb:BC000855.1 gb:AF044957.1 gb:NM_004547.2 NM_004547 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa NDUFB4 4710 NM_001168331 /// NM_004547 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 218227_at NM_012225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012225.1 /DEF=Homo sapiens nucleotide binding protein 2 (E.coli MinD like) (NUBP2), mRNA. /FEA=mRNA /GEN=NUBP2 /PROD=nucleotide binding protein 2 (E.coli MinD like) /DB_XREF=gi:6912539 /UG=Hs.256549 nucleotide binding protein 2 (E.coli MinD like) /FL=gb:BC002768.1 gb:AF118394.1 gb:NM_012225.1 NM_012225 nucleotide binding protein 2 NUBP2 10101 NM_001284501 /// NM_001284502 /// NM_012225 /// NR_104318 /// XM_005255025 /// XM_005255027 /// XM_005255028 /// XM_005255030 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 218228_s_at NM_025235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025235.1 /DEF=Homo sapiens tankyrase 2 (TNKL), mRNA. /FEA=mRNA /GEN=TNKL /PROD=tankyrase 2 /DB_XREF=gi:13376841 /UG=Hs.280776 tankyrase 2 /FL=gb:AF264912.1 gb:AF329696.1 gb:NM_025235.1 gb:AF342982.1 NM_025235 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 TNKS2 80351 NM_025235 /// XM_005270185 0000209 // protein polyubiquitination // inferred from direct assay /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred by curator /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0070213 // protein auto-ADP-ribosylation // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000242 // pericentriolar material // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218229_s_at NM_017542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017542.1 /DEF=Homo sapiens KIAA1513 protein (KIAA1513), mRNA. /FEA=mRNA /GEN=KIAA1513 /PROD=KIAA1513 protein /DB_XREF=gi:8923835 /UG=Hs.284227 KIAA1513 protein /FL=gb:NM_017542.1 NM_017542 pogo transposable element with KRAB domain POGK 57645 NM_017542 /// XM_005245370 /// XM_005245371 /// XM_005245372 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218230_at AL044651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044651 /FEA=EST /DB_XREF=gi:5432866 /DB_XREF=est:DKFZp434P082_s1 /CLONE=DKFZp434P082 /UG=Hs.301064 arfaptin 1 /FL=gb:U52521.1 gb:NM_014447.1 AL044651 ADP-ribosylation factor interacting protein 1 ARFIP1 27236 NM_001025593 /// NM_001025595 /// NM_001287431 /// NM_001287432 /// NM_001287433 /// NM_014447 0006886 // intracellular protein transport // inferred from direct assay /// 0050708 // regulation of protein secretion // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 218231_at NM_017567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017567.1 /DEF=Homo sapiens N-Acetylglucosamine kinase (HSA242910), mRNA. /FEA=mRNA /GEN=HSA242910 /PROD=N-Acetylglucosamine kinase /DB_XREF=gi:8923736 /UG=Hs.7036 N-Acetylglucosamine kinase /FL=gb:BC001029.1 gb:BC005371.1 gb:NM_017567.1 NM_017567 N-acetylglucosamine kinase NAGK 55577 NM_017567 /// XM_005264412 /// XM_005264413 /// XM_005264415 /// XM_006712045 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006051 // N-acetylmannosamine metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009384 // N-acylmannosamine kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0045127 // N-acetylglucosamine kinase activity // inferred from direct assay 218232_at NM_015991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015991.1 /DEF=Homo sapiens complement component 1, q subcomponent, alpha polypeptide (C1QA), mRNA. /FEA=mRNA /GEN=C1QA /PROD=complement component 1, q subcomponent, alphapolypeptide precursor /DB_XREF=gi:7705752 /UG=Hs.9641 complement component 1, q subcomponent, alpha polypeptide /FL=gb:AF260332.1 gb:AF135157.1 gb:NM_015991.1 NM_015991 complement component 1, q subcomponent, A chain C1QA 712 NM_015991 0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005602 // complement component C1 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218233_s_at NM_017601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017601.1 /DEF=Homo sapiens hypothetical protein DKFZp761H221 (DKFZp761H221), mRNA. /FEA=mRNA /GEN=DKFZp761H221 /PROD=hypothetical protein DKFZp761H221 /DB_XREF=gi:8922168 /UG=Hs.10702 hypothetical protein DKFZp761H221 /FL=gb:NM_017601.1 NM_017601 prickle homolog 4 (Drosophila) /// translocase of outer mitochondrial membrane 6 homolog (yeast) PRICKLE4 /// TOMM6 29964 /// 100188893 NM_001134493 /// NM_013397 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218234_at NM_016162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016162.1 /DEF=Homo sapiens candidate tumor suppressor p33 ING1 homolog (LOC51147), mRNA. /FEA=mRNA /GEN=LOC51147 /PROD=candidate tumor suppressor p33 ING1 homolog /DB_XREF=gi:7705860 /UG=Hs.108183 candidate tumor suppressor p33 ING1 homolog /FL=gb:AF063594.1 gb:AF110645.1 gb:NM_016162.1 NM_016162 inhibitor of growth family, member 4 ING4 51147 NM_001127582 /// NM_001127583 /// NM_001127584 /// NM_001127585 /// NM_001127586 /// NM_016162 /// NM_198287 /// XM_005253698 /// XR_242982 /// XR_242983 0006260 // DNA replication // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006473 // protein acetylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045926 // negative regulation of growth // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218235_s_at NM_016037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016037.1 /DEF=Homo sapiens CGI-94 protein (LOC51118), mRNA. /FEA=mRNA /GEN=LOC51118 /PROD=CGI-94 protein /DB_XREF=gi:7705808 /UG=Hs.111449 CGI-94 protein /FL=gb:BC005182.1 gb:AF151852.1 gb:NM_016037.1 gb:AF067802.1 NM_016037 UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) UTP11L 51118 NM_016037 0006364 // rRNA processing // not recorded /// 0007399 // nervous system development // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 2001272 // positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032040 // small-subunit processome // not recorded 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218236_s_at NM_005813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005813.2 /DEF=Homo sapiens protein kinase C, nu (PRKCN), mRNA. /FEA=mRNA /GEN=PRKCN /PROD=protein kinase C, nu /DB_XREF=gi:6563384 /UG=Hs.143460 protein kinase C, nu /FL=gb:AB015982.2 gb:NM_005813.2 NM_005813 protein kinase D3 PRKD3 23683 NM_005813 /// XM_005264237 /// XM_005264238 /// XM_006711978 /// XM_006711979 /// XM_006711980 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218237_s_at NM_030674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030674.1 /DEF=Homo sapiens amino acid transporter system A1 (ATA1), mRNA. /FEA=mRNA /GEN=ATA1 /PROD=amino acid transporter system A1 /DB_XREF=gi:13492978 /UG=Hs.18272 amino acid transporter system A1 /FL=gb:AF271070.1 gb:NM_030674.1 NM_030674 solute carrier family 38, member 1 SLC38A1 81539 NM_001077484 /// NM_001278387 /// NM_001278388 /// NM_001278389 /// NM_001278390 /// NM_030674 0001504 // neurotransmitter uptake // traceable author statement /// 0003333 // amino acid transmembrane transport // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0006868 // glutamine transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015804 // neutral amino acid transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005283 // sodium:amino acid symporter activity // non-traceable author statement /// 0015175 // neutral amino acid transmembrane transporter activity // non-traceable author statement /// 0015186 // L-glutamine transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 218238_at NM_012341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012341.1 /DEF=Homo sapiens GTP-binding protein (NGB), mRNA. /FEA=mRNA /GEN=NGB /PROD=GTP-binding protein /DB_XREF=gi:6912531 /UG=Hs.215766 GTP-binding protein /FL=gb:AF325353.1 gb:AF120334.1 gb:NM_012341.1 NM_012341 GTP binding protein 4 GTPBP4 23560 NM_012341 /// XM_006717437 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0033342 // negative regulation of collagen binding // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218239_s_at NM_012341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012341.1 /DEF=Homo sapiens GTP-binding protein (NGB), mRNA. /FEA=mRNA /GEN=NGB /PROD=GTP-binding protein /DB_XREF=gi:6912531 /UG=Hs.215766 GTP-binding protein /FL=gb:AF325353.1 gb:AF120334.1 gb:NM_012341.1 NM_012341 GTP binding protein 4 GTPBP4 23560 NM_012341 /// XM_006717437 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0015684 // ferrous iron transport // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0033342 // negative regulation of collagen binding // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218240_at NM_017595 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017595.1 /DEF=Homo sapiens I-kappa-B-interacting Ras-like protein 2 (KBRAS2), mRNA. /FEA=mRNA /GEN=KBRAS2 /PROD=I-kappa-B-interacting Ras-like protein 2 /DB_XREF=gi:8922150 /UG=Hs.22937 I-kappa-B-interacting Ras-like protein 2 /FL=gb:NM_017595.1 NM_017595 NFKB inhibitor interacting Ras-like 2 NKIRAS2 28511 NM_001001349 /// NM_001144927 /// NM_001144928 /// NM_001144929 /// NM_017595 /// XM_005257251 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 218241_at NM_005113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005113.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 5 (GOLGA5), mRNA. /FEA=mRNA /GEN=GOLGA5 /PROD=golgi autoantigen, golgin subfamily a, 5 /DB_XREF=gi:4826747 /UG=Hs.241572 golgi autoantigen, golgin subfamily a, 5 /FL=gb:AF085199.1 gb:NM_005113.1 NM_005113 golgin A5 GOLGA5 9950 NM_005113 0007030 // Golgi organization // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031985 // Golgi cisterna // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 218242_s_at NM_017635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017635.1 /DEF=Homo sapiens hypothetical protein FLJ20039 (FLJ20039), mRNA. /FEA=mRNA /GEN=FLJ20039 /PROD=hypothetical protein FLJ20039 /DB_XREF=gi:8923045 /UG=Hs.267448 hypothetical protein FLJ20039 /FL=gb:NM_017635.1 NM_017635 suppressor of variegation 4-20 homolog 1 (Drosophila) SUV420H1 51111 NM_016028 /// NM_017635 /// XM_005274035 /// XM_005274036 /// XM_005274037 /// XM_005274038 /// XM_006718581 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0042799 // histone methyltransferase activity (H4-K20 specific) // inferred from electronic annotation 218243_at NM_025158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025158.1 /DEF=Homo sapiens hypothetical protein FLJ22251 (FLJ22251), mRNA. /FEA=mRNA /GEN=FLJ22251 /PROD=hypothetical protein FLJ22251 /DB_XREF=gi:13376756 /UG=Hs.289064 hypothetical protein FLJ22251 /FL=gb:NM_025158.1 NM_025158 RUN and FYVE domain containing 1 RUFY1 80230 NM_001040451 /// NM_001040452 /// NM_025158 /// XM_005265993 /// XM_006714921 /// XM_006714922 /// XR_245276 /// XR_245277 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218244_at NM_017948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017948.1 /DEF=Homo sapiens hypothetical protein FLJ20736 (FLJ20736), mRNA. /FEA=mRNA /GEN=FLJ20736 /PROD=hypothetical protein FLJ20736 /DB_XREF=gi:8923662 /UG=Hs.48712 hypothetical protein FLJ20736 /FL=gb:NM_017948.1 NM_017948 nucleolar protein 8 NOL8 55035 NM_001256394 /// NM_017948 /// NR_046106 /// XM_006717166 /// XM_006717167 /// XM_006717168 /// XM_006717169 /// XM_006717170 /// XM_006717171 /// XM_006717172 /// XM_006717173 0006260 // DNA replication // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218245_at NM_015516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015516.1 /DEF=Homo sapiens hypothetical protein, estradiol-induced (E2IG4), mRNA. /FEA=mRNA /GEN=E2IG4 /PROD=hypothetical protein, estradiol-induced /DB_XREF=gi:7661667 /UG=Hs.8361 hypothetical protein, estradiol-induced /FL=gb:AF191019.1 gb:NM_015516.1 NM_015516 tsukushi, small leucine rich proteoglycan TSKU 25987 NM_001258210 /// NM_015516 /// XM_005273892 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021540 // corpus callosum morphogenesis // inferred from electronic annotation /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0021960 // anterior commissure morphogenesis // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0061073 // ciliary body morphogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218246_at NM_024544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024544.1 /DEF=Homo sapiens hypothetical protein FLJ12875 (FLJ12875), mRNA. /FEA=mRNA /GEN=FLJ12875 /PROD=hypothetical protein FLJ12875 /DB_XREF=gi:13375704 /UG=Hs.10101 hypothetical protein FLJ12875 /FL=gb:NM_024544.1 NM_024544 mitochondrial E3 ubiquitin protein ligase 1 MUL1 79594 NM_024544 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0010637 // negative regulation of mitochondrial fusion // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045824 // negative regulation of innate immune response // inferred from mutant phenotype /// 0050689 // negative regulation of defense response to virus by host // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051646 // mitochondrion localization // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071360 // cellular response to exogenous dsRNA // inferred from direct assay /// 0071650 // negative regulation of chemokine (C-C motif) ligand 5 production // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 1901028 // regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218247_s_at NM_016626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016626.1 /DEF=Homo sapiens hypothetical protein (LOC51320), mRNA. /FEA=mRNA /GEN=LOC51320 /PROD=hypothetical protein /DB_XREF=gi:7706165 /UG=Hs.12830 hypothetical protein /FL=gb:AF208855.1 gb:NM_016626.1 NM_016626 mex-3 RNA binding family member C MEX3C 51320 NM_016626 0003415 // chondrocyte hypertrophy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0097009 // energy homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218248_at NM_022074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022074.1 /DEF=Homo sapiens hypothetical protein FLJ22794 (FLJ22794), mRNA. /FEA=mRNA /GEN=FLJ22794 /PROD=hypothetical protein FLJ22794 /DB_XREF=gi:11545788 /UG=Hs.19525 hypothetical protein FLJ22794 /FL=gb:NM_022074.1 NM_022074 family with sequence similarity 111, member A FAM111A 63901 NM_001142519 /// NM_001142520 /// NM_001142521 /// NM_022074 /// NM_198847 0000087 // mitotic M phase // inferred from expression pattern /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218249_at NM_022494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022494.1 /DEF=Homo sapiens hypothetical protein FLJ21952 (FLJ21952), mRNA. /FEA=mRNA /GEN=FLJ21952 /PROD=hypothetical protein FLJ21952 /DB_XREF=gi:11968052 /UG=Hs.22353 hypothetical protein FLJ21952 /FL=gb:NM_022494.1 NM_022494 zinc finger, DHHC-type containing 6 ZDHHC6 64429 NM_022494 /// XM_005270051 /// XM_005270052 /// XM_006717948 /// XM_006717949 0018345 // protein palmitoylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218250_s_at NM_013354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013354.2 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 7 (CNOT7), mRNA. /FEA=mRNA /GEN=CNOT7 /PROD=CCR4-NOT transcription complex, subunit 7 /DB_XREF=gi:10518495 /UG=Hs.226318 CCR4-NOT transcription complex, subunit 7 /FL=gb:NM_013354.2 gb:L46722.1 NM_013354 CCR4-NOT transcription complex, subunit 7 CNOT7 29883 NM_013354 /// NM_054026 /// XM_005273481 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0000290 // deadenylation-dependent decapping of nuclear-transcribed mRNA // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay /// 0030014 // CCR4-NOT complex // non-traceable author statement 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218251_at NM_021242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021242.1 /DEF=Homo sapiens hypothetical protein STRAIT11499 (STRAIT11499), mRNA. /FEA=mRNA /GEN=STRAIT11499 /PROD=hypothetical protein STRAIT11499 /DB_XREF=gi:10864050 /UG=Hs.236556 hypothetical protein STRAIT11499 /FL=gb:NM_021242.1 NM_021242 MID1 interacting protein 1 MID1IP1 58526 NM_001098790 /// NM_001098791 /// NM_021242 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from sequence or structural similarity /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0046890 // regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0051258 // protein polymerization // inferred from sequence or structural similarity /// 0051351 // positive regulation of ligase activity // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 218252_at NM_018204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018204.1 /DEF=Homo sapiens cytoskeleton associated protein 2 (CKAP2), mRNA. /FEA=mRNA /GEN=CKAP2 /PROD=cytoskeleton associated protein 2 /DB_XREF=gi:8922641 /UG=Hs.24641 cytoskeleton associated protein 2 /FL=gb:AL136848.1 gb:NM_018204.1 NM_018204 cytoskeleton associated protein 2 CKAP2 26586 NM_001098525 /// NM_001286686 /// NM_001286687 /// NM_018204 /// XM_005266343 /// XM_005266344 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 218253_s_at NM_006893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006893.1 /DEF=Homo sapiens ligatin (LGTN), mRNA. /FEA=mRNA /GEN=LGTN /PROD=ligatin /DB_XREF=gi:11386190 /UG=Hs.274151 ligatin /FL=gb:NM_006893.1 gb:AF220417.2 NM_006893 eukaryotic translation initiation factor 2D EIF2D 1939 NM_001201478 /// NM_006893 /// XM_005277509 /// XM_006711196 0001731 // formation of translation preinitiation complex // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0032790 // ribosome disassembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 218254_s_at NM_016103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016103.1 /DEF=Homo sapiens GTP-binding protein Sara (LOC51128), mRNA. /FEA=mRNA /GEN=LOC51128 /PROD=GTP-binding protein Sara /DB_XREF=gi:7705826 /UG=Hs.279582 GTP-binding protein Sara /FL=gb:AF092130.1 gb:NM_016103.1 NM_016103 secretion associated, Ras related GTPase 1B SAR1B 51128 NM_001033503 /// NM_016103 /// XM_006714641 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218255_s_at NM_022452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022452.1 /DEF=Homo sapiens hypothetical protein FLJ11618 (FLJ11618), mRNA. /FEA=mRNA /GEN=FLJ11618 /PROD=hypothetical protein FLJ11618 /DB_XREF=gi:11967986 /UG=Hs.77735 hypothetical protein FLJ11618 /FL=gb:NM_022452.1 NM_022452 fibrosin FBRS 64319 NM_001105079 /// NM_022452 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 218256_s_at NM_017426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017426.1 /DEF=Homo sapiens nucleoporin p54 (NUP54), mRNA. /FEA=mRNA /GEN=NUP54 /PROD=nucleoporin p54 /DB_XREF=gi:8393857 /UG=Hs.9082 nucleoporin p54 /FL=gb:AF157322.1 gb:NM_017426.1 NM_017426 nucleoporin 54kDa NUP54 53371 NM_001278603 /// NM_017426 /// NR_103780 /// NR_103781 /// NR_103782 /// XM_006714236 /// XM_006714237 /// XM_006714238 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218257_s_at NM_020120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020120.1 /DEF=Homo sapiens UDP-glucose:glycoprotein glucosyltransferase 1 (HUGT1), mRNA. /FEA=mRNA /GEN=HUGT1 /PROD=UDP-glucose:glycoprotein glucosyltransferase 1 /DB_XREF=gi:9910279 /UG=Hs.105794 UDP-glucose:glycoprotein glucosyltransferase 1 /FL=gb:AF227905.1 gb:NM_020120.1 NM_020120 UDP-glucose glycoprotein glucosyltransferase 1 UGGT1 56886 NM_001025777 /// NM_020120 /// NR_027671 /// XM_006712634 /// XM_006712635 /// XM_006712636 0006457 // protein folding // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0097359 // UDP-glucosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003980 // UDP-glucose:glycoprotein glucosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay 218258_at NM_015972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015972.1 /DEF=Homo sapiens RNA polymerase I 16 kDa subunit (LOC51082), mRNA. /FEA=mRNA /GEN=LOC51082 /PROD=RNA polymerase I 16 kDa subunit /DB_XREF=gi:7705739 /UG=Hs.106127 RNA polymerase I 16 kDa subunit /FL=gb:BC000889.1 gb:AF077044.1 gb:NM_015972.1 NM_015972 polymerase (RNA) I polypeptide D, 16kDa POLR1D 51082 NM_001206559 /// NM_015972 /// NM_152705 /// XM_005266412 /// XM_005266414 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement 0001054 // RNA polymerase I activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 218259_at NM_014048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014048.1 /DEF=Homo sapiens KIAA1243 protein (KIAA1243), mRNA. /FEA=mRNA /GEN=KIAA1243 /PROD=NPD001 protein /DB_XREF=gi:7662513 /UG=Hs.151076 KIAA1243 protein /FL=gb:AF078853.1 gb:NM_014048.1 NM_014048 MKL/myocardin-like 2 MKL2 57496 NM_014048 /// XM_005255451 /// XM_005255452 /// XM_005255453 /// XM_005255455 /// XM_005255457 /// XM_006720908 /// XM_006720909 /// XM_006720910 /// XM_006720911 /// XM_006720912 /// XM_006720913 /// XM_006720914 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0010467 // gene expression // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045844 // positive regulation of striated muscle tissue development // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218260_at NM_024050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024050.1 /DEF=Homo sapiens hypothetical protein MGC2594 (MGC2594), mRNA. /FEA=mRNA /GEN=MGC2594 /PROD=hypothetical protein MGC2594 /DB_XREF=gi:13129015 /UG=Hs.181551 hypothetical protein MGC2594 /FL=gb:BC000615.1 gb:NM_024050.1 NM_024050 DET1 and DDB1 associated 1 DDA1 79016 NM_024050 218261_at NM_005498 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005498.2 /DEF=Homo sapiens adaptor-related protein complex 1, mu 2 subunit (AP1M2), mRNA. /FEA=mRNA /GEN=AP1M2 /PROD=adaptor-related protein complex 1, mu 2 subunit /DB_XREF=gi:9506796 /UG=Hs.18894 adaptor-related protein complex 1, mu 2 subunit /FL=gb:BC003387.1 gb:BC003612.1 gb:BC005021.1 gb:AF020797.2 gb:NM_005498.2 NM_005498 adaptor-related protein complex 1, mu 2 subunit AP1M2 10053 NM_005498 /// XM_005259701 0006605 // protein targeting // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 218262_at NM_022762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022762.1 /DEF=Homo sapiens hypothetical protein FLJ22318 (FLJ22318), mRNA. /FEA=mRNA /GEN=FLJ22318 /PROD=hypothetical protein FLJ22318 /DB_XREF=gi:12232432 /UG=Hs.22753 hypothetical protein FLJ22318 /FL=gb:NM_022762.1 NM_022762 required for meiotic nuclear division 5 homolog B (S. cerevisiae) RMND5B 64777 NM_001288794 /// NM_001288795 /// NM_022762 /// XM_005265969 /// XM_005265971 /// XM_005265972 0005515 // protein binding // inferred from electronic annotation 218263_s_at NM_021211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021211.1 /DEF=Homo sapiens transposon-derived Buster1 transposase-like protein (LOC58486), mRNA. /FEA=mRNA /GEN=LOC58486 /PROD=transposon-derived Buster1 transposase-likeprotein /DB_XREF=gi:10864022 /UG=Hs.25726 transposon-derived Buster1 transposase-like protein /FL=gb:NM_021211.1 gb:AF205600.1 NM_021211 zinc finger, BED-type containing 5 ZBED5 58486 NM_001143667 /// NM_021211 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218264_at NM_016567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016567.1 /DEF=Homo sapiens cdk inhibitor p21 binding protein (TOK-1), mRNA. /FEA=mRNA /GEN=TOK-1 /PROD=cdk inhibitor p21 binding protein /DB_XREF=gi:7706580 /UG=Hs.279862 cdk inhibitor p21 binding protein /FL=gb:AB040450.1 gb:NM_016567.1 NM_016567 BRCA2 and CDKN1A interacting protein BCCIP 56647 NM_016567 /// NM_078468 /// NM_078469 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0061101 // neuroendocrine cell differentiation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019207 // kinase regulator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 218265_at NM_024077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024077.1 /DEF=Homo sapiens hypothetical protein MGC3156 (MGC3156), mRNA. /FEA=mRNA /GEN=MGC3156 /PROD=hypothetical protein MGC3156 /DB_XREF=gi:13129065 /UG=Hs.288141 hypothetical protein MGC3156 /FL=gb:AL136881.1 gb:NM_024077.1 NM_024077 SECIS binding protein 2 SECISBP2 79048 NM_001282688 /// NM_001282689 /// NM_001282690 /// NM_024077 /// XM_005252193 /// XM_005252195 /// XM_005252196 /// XM_005252198 /// XM_005252202 /// XM_006717282 /// XR_428537 0006412 // translation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0035368 // selenocysteine insertion sequence binding // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218266_s_at NM_014286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014286.1 /DEF=Homo sapiens frequenin (Drosophila) homolog (FREQ), mRNA. /FEA=mRNA /GEN=FREQ /PROD=frequenin (Drosophila) homolog /DB_XREF=gi:7657366 /UG=Hs.301760 frequenin (Drosophila) homolog /FL=gb:BC004856.1 gb:AF186409.1 gb:NM_014286.1 NM_014286 neuronal calcium sensor 1 NCS1 23413 NM_001128826 /// NM_014286 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218267_at NM_016550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016550.1 /DEF=Homo sapiens from HeLa cyclin-dependent kinase 2 interacting protein (CINP), mRNA. /FEA=mRNA /GEN=CINP /PROD=from HeLa cyclin-dependent kinase 2 interactingprotein /DB_XREF=gi:7705325 /UG=Hs.38205 from HeLa cyclin-dependent kinase 2 interacting protein /FL=gb:BC000600.1 gb:AF228148.1 gb:AF228149.1 gb:NM_016550.1 NM_016550 cyclin-dependent kinase 2 interacting protein CINP 51550 NM_001177611 /// NM_001177612 /// NM_032630 /// XM_005267753 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218268_at NM_022771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022771.1 /DEF=Homo sapiens hypothetical protein FLJ12085 (FLJ12085), mRNA. /FEA=mRNA /GEN=FLJ12085 /PROD=hypothetical protein FLJ12085 /DB_XREF=gi:12232450 /UG=Hs.48827 hypothetical protein FLJ12085 /FL=gb:NM_022771.1 NM_022771 TBC1 domain family, member 15 TBC1D15 64786 NM_001146213 /// NM_001146214 /// NM_022771 /// NR_027449 /// XM_006719563 /// XM_006719564 /// XM_006719565 /// XM_006719566 /// XM_006719567 0032313 // regulation of Rab GTPase activity // inferred from sequence or structural similarity /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 218269_at NM_013235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013235.1 /DEF=Homo sapiens putative ribonuclease III (RNASE3L), mRNA. /FEA=mRNA /GEN=RNASE3L /PROD=putative ribonuclease III /DB_XREF=gi:7106396 /UG=Hs.49163 putative ribonuclease III /FL=gb:AF116910.1 gb:NM_013235.1 gb:AF189011.1 NM_013235 drosha, ribonuclease type III DROSHA 29102 NM_001100412 /// NM_013235 /// XM_005248291 /// XM_005248292 /// XM_005248293 /// XM_005248294 0006396 // RNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010586 // miRNA metabolic process // inferred from electronic annotation /// 0016075 // rRNA catabolic process // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from direct assay /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0031054 // pre-miRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from electronic annotation /// 0004525 // ribonuclease III activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218270_at NM_024540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024540.1 /DEF=Homo sapiens hypothetical protein FLJ20917 (FLJ20917), mRNA. /FEA=mRNA /GEN=FLJ20917 /PROD=hypothetical protein FLJ20917 /DB_XREF=gi:13375698 /UG=Hs.9265 hypothetical protein FLJ20917 /FL=gb:NM_024540.1 NM_024540 mitochondrial ribosomal protein L24 MRPL24 79590 NM_024540 /// NM_145729 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 218271_s_at NM_018622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018622.1 /DEF=Homo sapiens presenilins associated rhomboid-like protein (PRO2207), mRNA. /FEA=mRNA /GEN=PRO2207 /PROD=presenilins associated rhomboid-like protein /DB_XREF=gi:8924133 /UG=Hs.13094 presenilins associated rhomboid-like protein /FL=gb:AF197937.1 gb:AF116692.1 gb:NM_018622.1 NM_018622 presenilin associated, rhomboid-like PARL 55486 NM_001037639 /// NM_001037640 /// NM_018622 /// XM_005247582 /// XM_005247583 /// XM_005247584 /// XM_005247585 /// XM_005247586 /// XM_005247587 0006508 // proteolysis // inferred from electronic annotation /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218272_at NM_017931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017931.1 /DEF=Homo sapiens hypothetical protein FLJ20699 (FLJ20699), mRNA. /FEA=mRNA /GEN=FLJ20699 /PROD=hypothetical protein FLJ20699 /DB_XREF=gi:8923627 /UG=Hs.15125 hypothetical protein FLJ20699 /FL=gb:NM_017931.1 NM_017931 tetratricopeptide repeat domain 38 TTC38 55020 NM_017931 /// XR_244380 218273_s_at NM_018444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018444.1 /DEF=Homo sapiens pyruvate dehydrogenase phosphatase (PDP), mRNA. /FEA=mRNA /GEN=PDP /PROD=pyruvate dehydrogenase phosphatase /DB_XREF=gi:8923959 /UG=Hs.22265 pyruvate dehydrogenase phosphatase /FL=gb:AF155661.1 gb:NM_018444.1 NM_018444 pyruvate dehyrogenase phosphatase catalytic subunit 1 PDP1 54704 NM_001161778 /// NM_001161779 /// NM_001161780 /// NM_001161781 /// NM_018444 /// XM_005250986 /// XM_006716592 0006090 // pyruvate metabolic process // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004741 // [pyruvate dehydrogenase (lipoamide)] phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218274_s_at NM_018089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018089.1 /DEF=Homo sapiens hypothetical protein FLJ10415 (FLJ10415), mRNA. /FEA=mRNA /GEN=FLJ10415 /PROD=hypothetical protein FLJ10415 /DB_XREF=gi:8922412 /UG=Hs.23788 hypothetical protein FLJ10415 /FL=gb:BC000238.1 gb:NM_018089.1 NM_018089 ankyrin repeat and zinc finger domain containing 1 ANKZF1 55139 NM_001042410 /// NM_001282792 /// NM_018089 /// XM_005246663 /// XR_427096 /// XR_427097 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218275_at NM_012140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012140.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (SLC25A10), mRNA. /FEA=mRNA /GEN=SLC25A10 /PROD=solute carrier family 25 (mitochondrial carrier;dicarboxylate transporter), member 10 /DB_XREF=gi:6912333 /UG=Hs.285829 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 /FL=gb:NM_012140.1 NM_012140 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 SLC25A10 1468 NM_001270888 /// NM_001270953 /// NM_012140 /// XM_005257074 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0015709 // thiosulfate transport // inferred from electronic annotation /// 0015743 // malate transport // inferred from electronic annotation /// 0015744 // succinate transport // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035435 // phosphate ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement /// 0071422 // succinate transmembrane transport // inferred from electronic annotation /// 0071423 // malate transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005310 // dicarboxylic acid transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015114 // phosphate ion transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015117 // thiosulfate transmembrane transporter activity // inferred from electronic annotation /// 0015140 // malate transmembrane transporter activity // inferred from electronic annotation /// 0015141 // succinate transmembrane transporter activity // inferred from electronic annotation /// 0015291 // secondary active transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 218276_s_at NM_021818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021818.1 /DEF=Homo sapiens WW Domain-Containing Gene (WW45), mRNA. /FEA=mRNA /GEN=WW45 /PROD=WW Domain-Containing Gene /DB_XREF=gi:11141888 /UG=Hs.288906 WW Domain-Containing Gene /FL=gb:NM_021818.1 NM_021818 salvador family WW domain containing protein 1 SAV1 60485 NM_021818 0001942 // hair follicle development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from sequence or structural similarity /// 0035329 // hippo signaling // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046620 // regulation of organ growth // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0060575 // intestinal epithelial cell differentiation // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 218277_s_at NM_024612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024612.1 /DEF=Homo sapiens hypothetical protein FLJ22060 (FLJ22060), mRNA. /FEA=mRNA /GEN=FLJ22060 /PROD=hypothetical protein FLJ22060 /DB_XREF=gi:13375824 /UG=Hs.29403 hypothetical protein FLJ22060 /FL=gb:NM_024612.1 NM_024612 DEAH (Asp-Glu-Ala-His) box polypeptide 40 DHX40 79665 NM_001166301 /// NM_024612 /// XM_003846599 /// XM_006722083 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218278_at NM_018093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018093.1 /DEF=Homo sapiens hypothetical protein FLJ10439 (FLJ10439), mRNA. /FEA=mRNA /GEN=FLJ10439 /PROD=hypothetical protein FLJ10439 /DB_XREF=gi:8922421 /UG=Hs.3487 hypothetical protein FLJ10439 /FL=gb:NM_018093.1 NM_018093 WD repeat domain 74 WDR74 54663 NM_018093 /// XM_005274055 0001825 // blastocyst formation // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218279_s_at BC001629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001629.1 /DEF=Homo sapiens, H2A histone family, member O, clone MGC:2238, mRNA, complete cds. /FEA=mRNA /PROD=H2A histone family, member O /DB_XREF=gi:12804444 /UG=Hs.795 H2A histone family, member O /FL=gb:BC001629.1 gb:L19779.1 gb:NM_003516.1 BC001629 218280_x_at NM_003516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003516.1 /DEF=Homo sapiens H2A histone family, member O (H2AFO), mRNA. /FEA=mRNA /GEN=H2AFO /PROD=H2A histone family, member O /DB_XREF=gi:4504250 /UG=Hs.795 H2A histone family, member O /FL=gb:BC001629.1 gb:L19779.1 gb:NM_003516.1 NM_003516 histone cluster 2, H2aa3 /// histone cluster 2, H2aa4 HIST2H2AA3 /// HIST2H2AA4 8337 /// 723790 NM_001040874 /// NM_003516 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218281_at NM_016055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016055.1 /DEF=Homo sapiens CGI-118 protein (LOC51642), mRNA. /FEA=mRNA /GEN=LOC51642 /PROD=CGI-118 protein /DB_XREF=gi:7706332 /UG=Hs.82389 CGI-118 protein /FL=gb:AF151876.1 gb:NM_016055.1 NM_016055 mitochondrial ribosomal protein L48 MRPL48 51642 NM_001030046 /// NM_016055 /// XM_005274050 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218282_at NM_018217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018217.1 /DEF=Homo sapiens hypothetical protein FLJ10783 (FLJ10783), mRNA. /FEA=mRNA /GEN=FLJ10783 /PROD=hypothetical protein FLJ10783 /DB_XREF=gi:8922666 /UG=Hs.93871 hypothetical protein FLJ10783 /FL=gb:BC001371.1 gb:NM_018217.1 NM_018217 ER degradation enhancer, mannosidase alpha-like 2 EDEM2 55741 NM_001145025 /// NM_018217 /// NR_026728 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation 218283_at NM_016305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016305.1 /DEF=Homo sapiens kiaa-iso protein (LOC51188), mRNA. /FEA=mRNA /GEN=LOC51188 /PROD=kiaa-iso protein /DB_XREF=gi:10047103 /UG=Hs.9774 kiaa-iso protein /FL=gb:NM_016305.1 gb:AF201950.1 NM_016305 synovial sarcoma translocation gene on chromosome 18-like 2 SS18L2 51188 NM_016305 218284_at NM_015400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015400.1 /DEF=Homo sapiens DKFZP586N0721 protein (DKFZP586N0721), mRNA. /FEA=mRNA /GEN=DKFZP586N0721 /PROD=DKFZP586N0721 protein /DB_XREF=gi:7661691 /UG=Hs.99843 DKFZP586N0721 protein /FL=gb:BC000414.1 gb:AF151027.1 gb:NM_015400.1 NM_015400 SMAD family member 3 SMAD3 4088 NM_001145102 /// NM_001145103 /// NM_001145104 /// NM_005902 /// XM_006720506 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006955 // immune response // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016202 // regulation of striated muscle tissue development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032916 // positive regulation of transforming growth factor beta3 production // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060290 // transdifferentiation // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097296 // activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from mutant phenotype /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction 218285_s_at NM_020139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020139.1 /DEF=Homo sapiens oxidoreductase UCPA (LOC56898), mRNA. /FEA=mRNA /GEN=LOC56898 /PROD=oxidoreductase UCPA /DB_XREF=gi:10047131 /UG=Hs.124696 oxidoreductase UCPA /FL=gb:NM_020139.1 gb:AF164790.1 NM_020139 3-hydroxybutyrate dehydrogenase, type 2 BDH2 56898 NM_020139 /// XM_005263140 /// XM_006714274 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019290 // siderophore biosynthetic process // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0042168 // heme metabolic process // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003858 // 3-hydroxybutyrate dehydrogenase activity // inferred from direct assay /// 0008667 // 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from sequence or structural similarity /// 0051287 // NAD binding // inferred from direct assay 218286_s_at NM_014245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014245.1 /DEF=Homo sapiens ring finger protein 7 (RNF7), mRNA. /FEA=mRNA /GEN=RNF7 /PROD=ring finger protein 7 /DB_XREF=gi:7657521 /UG=Hs.14084 ring finger protein 7 /FL=gb:AF092878.1 gb:AF164679.1 gb:NM_014245.1 NM_014245 ring finger protein 7 RNF7 9616 NM_001201370 /// NM_014245 /// NM_183063 /// NM_183237 /// NR_037702 /// NR_037703 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045116 // protein neddylation // inferred from direct assay /// 0051775 // response to redox state // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019788 // NEDD8 ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218287_s_at NM_012199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012199.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2C, 1 (EIF2C1), mRNA. /FEA=mRNA /GEN=EIF2C1 /PROD=eukaryotic translation initiation factor 2C, 1 /DB_XREF=gi:6912351 /UG=Hs.14520 eukaryotic translation initiation factor 2C, 1 /FL=gb:AF093097.1 gb:NM_012199.1 NM_012199 argonaute RISC catalytic component 1 AGO1 26523 NM_012199 /// XM_006710575 0000956 // nuclear-transcribed mRNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0035068 // micro-ribonucleoprotein complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218288_s_at NM_021825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021825.1 /DEF=Homo sapiens hypothetical protein MDS025 (MDS025), mRNA. /FEA=mRNA /GEN=MDS025 /PROD=hypothetical protein MDS025 /DB_XREF=gi:11141900 /UG=Hs.154938 hypothetical protein MDS025 /FL=gb:AF182412.1 gb:AF182424.1 gb:NM_021825.1 gb:AF271782.1 gb:AL136791.1 NM_021825 coiled-coil domain containing 90B CCDC90B 60492 NM_001286116 /// NM_001286117 /// NM_001286118 /// NM_001286119 /// NM_001286120 /// NM_021825 /// XM_005274152 /// XM_005274154 /// XM_005274156 /// XM_005274159 /// XM_006718654 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218289_s_at NM_024818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024818.1 /DEF=Homo sapiens hypothetical protein FLJ23251 (FLJ23251), mRNA. /FEA=mRNA /GEN=FLJ23251 /PROD=hypothetical protein FLJ23251 /DB_XREF=gi:13376211 /UG=Hs.170737 hypothetical protein FLJ23251 /FL=gb:AL136757.1 gb:NM_024818.1 NM_024818 ubiquitin-like modifier activating enzyme 5 UBA5 79876 NM_024818 /// NM_198329 /// XM_005247787 /// XM_006713752 0008152 // metabolic process // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071569 // protein ufmylation // inferred from direct assay /// 0071569 // protein ufmylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016235 // aggresome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0071566 // UFM1 activating enzyme activity // inferred from direct assay 218290_at NM_018049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018049.1 /DEF=Homo sapiens hypothetical protein FLJ10297 (FLJ10297), mRNA. /FEA=mRNA /GEN=FLJ10297 /PROD=hypothetical protein FLJ10297 /DB_XREF=gi:8922332 /UG=Hs.173739 hypothetical protein FLJ10297 /FL=gb:BC003084.1 gb:NM_018049.1 NM_018049 microRNA 6789 /// pleckstrin homology domain containing, family J member 1 MIR6789 /// PLEKHJ1 55111 /// 102466736 NM_018049 /// NR_106847 /// XM_005259591 /// XM_006722784 0005543 // phospholipid binding // inferred from electronic annotation 218291_at NM_014017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014017.1 /DEF=Homo sapiens HSPC003 protein (HSPC003), mRNA. /FEA=mRNA /GEN=HSPC003 /PROD=HSPC003 protein /DB_XREF=gi:7661727 /UG=Hs.25635 HSPC003 protein /FL=gb:AF070659.1 gb:NM_014017.1 NM_014017 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 LAMTOR2 28956 NM_001145264 /// NM_014017 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016049 // cell growth // inferred from mutant phenotype /// 0016266 // O-glycan processing // traceable author statement /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218292_s_at NM_016203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016203.1 /DEF=Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), mRNA. /FEA=mRNA /GEN=PRKAG2 /PROD=protein kinase, AMP-activated, gamma 2non-catalytic subunit /DB_XREF=gi:7705390 /UG=Hs.259842 protein kinase, AMP-activated, gamma 2 non-catalytic subunit /FL=gb:AF087875.1 gb:AB025580.1 gb:NM_016203.1 NM_016203 protein kinase, AMP-activated, gamma 2 non-catalytic subunit PRKAG2 51422 NM_001040633 /// NM_016203 /// NM_024429 /// XM_005250002 /// XM_005250003 /// XM_005250004 /// XM_005250005 /// XM_005250006 /// XM_005250007 /// XM_005250009 /// XM_006716021 0005977 // glycogen metabolic process // inferred from mutant phenotype /// 0006110 // regulation of glycolytic process // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0016126 // sterol biosynthetic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046320 // regulation of fatty acid oxidation // traceable author statement /// 0046324 // regulation of glucose import // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from mutant phenotype /// 0008607 // phosphorylase kinase regulator activity // inferred from mutant phenotype /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030295 // protein kinase activator activity // inferred from mutant phenotype /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay 218293_x_at AW589982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW589982 /FEA=EST /DB_XREF=gi:7277107 /DB_XREF=est:hg28c09.x1 /CLONE=IMAGE:2946928 /UG=Hs.271623 nucleoporin 50kD /FL=gb:AF267865.1 gb:AF107840.1 gb:NM_007172.1 gb:AF116624.1 AW589982 nucleoporin 50kDa NUP50 10762 NM_007172 /// NM_153645 /// XM_005261312 /// XM_005261313 /// XM_005261314 /// XM_006724103 /// XM_006724104 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218294_s_at AF267865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF267865.1 /DEF=Homo sapiens DC41 mRNA, complete cds. /FEA=mRNA /PROD=DC41 /DB_XREF=gi:12006056 /UG=Hs.271623 nucleoporin 50kD /FL=gb:AF267865.1 gb:AF107840.1 gb:NM_007172.1 gb:AF116624.1 AF267865 nucleoporin 50kDa NUP50 10762 NM_007172 /// NM_153645 /// XM_005261312 /// XM_005261313 /// XM_005261314 /// XM_006724103 /// XM_006724104 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218295_s_at NM_007172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007172.1 /DEF=Homo sapiens nucleoporin 50kD (NUP50), mRNA. /FEA=mRNA /GEN=NUP50 /PROD=nucleoporin 50kD /DB_XREF=gi:6005817 /UG=Hs.271623 nucleoporin 50kD /FL=gb:AF267865.1 gb:AF107840.1 gb:NM_007172.1 gb:AF116624.1 NM_007172 nucleoporin 50kDa NUP50 10762 NM_007172 /// NM_153645 /// XM_005261312 /// XM_005261313 /// XM_005261314 /// XM_006724103 /// XM_006724104 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218296_x_at NM_018116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018116.1 /DEF=Homo sapiens hypothetical protein FLJ10504 (FLJ10504), mRNA. /FEA=mRNA /GEN=FLJ10504 /PROD=hypothetical protein FLJ10504 /DB_XREF=gi:8922469 /UG=Hs.279763 hypothetical protein FLJ10504 /FL=gb:NM_018116.1 NM_018116 misato 1, mitochondrial distribution and morphology regulator /// misato family member 2, pseudogene MSTO1 /// MSTO2P 55154 /// 100129405 NM_001256532 /// NM_001256533 /// NM_018116 /// NR_024117 /// NR_046292 /// NR_046293 /// NR_046294 /// NR_046295 /// XM_006711412 /// XM_006711413 /// XM_006711414 /// XM_006711415 /// XM_006711416 /// XM_006711417 /// XM_006711418 /// XM_006711419 /// XM_006711420 /// XM_006711421 /// XM_006711422 /// XM_006711423 /// XM_006711424 /// XM_006711425 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0048311 // mitochondrion distribution // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 218297_at NM_024948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024948.1 /DEF=Homo sapiens hypothetical protein FLJ13397 (FLJ13397), mRNA. /FEA=mRNA /GEN=FLJ13397 /PROD=hypothetical protein FLJ13397 /DB_XREF=gi:13376430 /UG=Hs.285107 hypothetical protein FLJ13397 /FL=gb:AF063600.1 gb:NM_024948.1 NM_024948 family with sequence similarity 188, member A FAM188A 80013 NM_024948 /// XM_005252598 /// XM_005252600 /// XM_005252601 /// XM_005252602 /// XM_006717508 /// XR_428647 0006915 // apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218298_s_at NM_024952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024952.1 /DEF=Homo sapiens hypothetical protein FLJ20950 (FLJ20950), mRNA. /FEA=mRNA /GEN=FLJ20950 /PROD=hypothetical protein FLJ20950 /DB_XREF=gi:13376436 /UG=Hs.285673 hypothetical protein FLJ20950 /FL=gb:NM_024952.1 NM_024952 chromosome 14 open reading frame 159 C14orf159 80017 NM_001102366 /// NM_001102367 /// NM_001102368 /// NM_001102369 /// NM_001286470 /// NM_001286471 /// NM_001286472 /// NM_001286473 /// NM_024952 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004307 // ethanolaminephosphotransferase activity // traceable author statement 218299_at NM_022338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022338.1 /DEF=Homo sapiens chromosome 11 open reading frame 24 (C11ORF24), mRNA. /FEA=mRNA /GEN=C11ORF24 /PROD=chromosome 11 open reading frame 24 /DB_XREF=gi:11641238 /UG=Hs.303025 chromosome 11 open reading frame 24 /FL=gb:AF264781.1 gb:NM_022338.1 NM_022338 chromosome 11 open reading frame 24 C11orf24 53838 NM_022338 /// XM_005274053 /// XM_005274054 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218300_at NM_024516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024516.1 /DEF=Homo sapiens hypothetical protein MGC4606 (MGC4606), mRNA. /FEA=mRNA /GEN=MGC4606 /PROD=hypothetical protein MGC4606 /DB_XREF=gi:13375653 /UG=Hs.30661 hypothetical protein MGC4606 /FL=gb:BC003640.1 gb:NM_024516.1 NM_024516 PAXIP1 associated glutamate-rich protein 1 PAGR1 79447 NM_024516 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218301_at NM_018226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018226.1 /DEF=Homo sapiens arginyl aminopeptidase (aminopeptidase B)-like 1 (RNPEPL1), mRNA. /FEA=mRNA /GEN=RNPEPL1 /PROD=arginyl aminopeptidase (aminopeptidase B)-like1 /DB_XREF=gi:8922680 /UG=Hs.5345 arginyl aminopeptidase (aminopeptidase B)-like 1 /FL=gb:AF300795.1 gb:NM_018226.1 NM_018226 arginyl aminopeptidase (aminopeptidase B)-like 1 RNPEPL1 57140 NM_018226 /// XM_005247036 0006508 // proteolysis // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218302_at NM_018468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018468.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS033 (MDS033), mRNA. /FEA=mRNA /GEN=MDS033 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS033 /DB_XREF=gi:8923937 /UG=Hs.54960 uncharacterized hematopoietic stemprogenitor cells protein MDS033 /FL=gb:AF220053.1 gb:NM_018468.1 NM_018468 presenilin enhancer gamma secretase subunit PSENEN 55851 NM_001281532 /// NM_172341 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218303_x_at NM_016618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016618.1 /DEF=Homo sapiens hypothetical protein (LOC51315), mRNA. /FEA=mRNA /GEN=LOC51315 /PROD=hypothetical protein /DB_XREF=gi:7706155 /UG=Hs.5721 hypothetical protein /FL=gb:AF208845.1 gb:AF217520.1 gb:NM_016618.1 NM_016618 lysine-rich coiled-coil 1 KRCC1 51315 NM_016618 /// XM_005264360 218304_s_at NM_022776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022776.1 /DEF=Homo sapiens hypothetical protein FLJ13164 (FLJ13164), mRNA. /FEA=mRNA /GEN=FLJ13164 /PROD=hypothetical protein FLJ13164 /DB_XREF=gi:12232460 /UG=Hs.61260 hypothetical protein FLJ13164 /FL=gb:NM_022776.1 NM_022776 oxysterol binding protein-like 11 OSBPL11 114885 NM_022776 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from mutant phenotype 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 218305_at NM_024658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024658.1 /DEF=Homo sapiens hypothetical protein FLJ23338 (FLJ23338), mRNA. /FEA=mRNA /GEN=FLJ23338 /PROD=hypothetical protein FLJ23338 /DB_XREF=gi:13375908 /UG=Hs.61790 hypothetical protein FLJ23338 /FL=gb:BC003690.1 gb:NM_024658.1 NM_024658 importin 4 IPO4 79711 NM_024658 /// NR_051979 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation 218306_s_at NM_003922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003922.1 /DEF=Homo sapiens hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 (HERC1), mRNA. /FEA=mRNA /GEN=HERC1 /PROD=guanine nucleotide exchange factor p532 /DB_XREF=gi:4557025 /UG=Hs.76127 hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 /FL=gb:U50078.1 gb:NM_003922.1 NM_003922 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 HERC1 8925 NM_003922 /// XM_005254742 /// XM_005254743 /// XM_005254746 /// XM_005254747 /// XM_006720728 /// XR_243129 0006810 // transport // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 218307_at NM_018346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018346.1 /DEF=Homo sapiens hypothetical protein FLJ11164 (FLJ11164), mRNA. /FEA=mRNA /GEN=FLJ11164 /PROD=hypothetical protein FLJ11164 /DB_XREF=gi:8922910 /UG=Hs.8033 hypothetical protein FLJ11164 /FL=gb:NM_018346.1 NM_018346 radical S-adenosyl methionine domain containing 1 RSAD1 55316 NM_018346 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004109 // coproporphyrinogen oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 218308_at NM_006342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006342.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 3 (TACC3), mRNA. /FEA=mRNA /GEN=TACC3 /PROD=transforming acidic coiled-coil containingprotein 3 /DB_XREF=gi:5454101 /UG=Hs.104019 transforming, acidic coiled-coil containing protein 3 /FL=gb:AF093543.1 gb:NM_006342.1 NM_006342 transforming, acidic coiled-coil containing protein 3 TACC3 10460 NM_006342 /// XM_005247929 /// XM_005247930 /// XM_006713855 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030953 // astral microtubule organization // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 218309_at NM_018584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018584.1 /DEF=Homo sapiens hypothetical protein PRO1489 (PRO1489), mRNA. /FEA=mRNA /GEN=PRO1489 /PROD=hypothetical protein PRO1489 /DB_XREF=gi:8924051 /UG=Hs.107767 hypothetical protein PRO1489 /FL=gb:AF116637.1 gb:NM_018584.1 NM_018584 calcium/calmodulin-dependent protein kinase II inhibitor 1 CAMK2N1 55450 NM_018584 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0008427 // calcium-dependent protein kinase inhibitor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 218310_at NM_014504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014504.1 /DEF=Homo sapiens putative Rab5 GDPGTP exchange factor homologue (RABEX5), mRNA. /FEA=mRNA /GEN=RABEX5 /PROD=putative Rab5 GDPGTP exchange factor homologue /DB_XREF=gi:7657495 /UG=Hs.187660 putative Rab5 GDPGTP exchange factor homologue /FL=gb:NM_014504.1 NM_014504 potassium channel tetramerization domain containing 7 /// RAB guanine nucleotide exchange factor (GEF) 1 KCTD7 /// RABGEF1 27342 /// 154881 NM_001167961 /// NM_001287060 /// NM_001287061 /// NM_001287062 /// NM_014504 /// NM_153033 /// NR_104676 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218311_at NM_003618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003618.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3), mRNA. /FEA=mRNA /GEN=MAP4K3 /PROD=mitogen-activated protein kinase kinase kinasekinase 3 /DB_XREF=gi:4506376 /UG=Hs.227400 mitogen-activated protein kinase kinase kinase kinase 3 /FL=gb:AF000145.1 gb:NM_003618.1 NM_003618 mitogen-activated protein kinase kinase kinase kinase 3 MAP4K3 8491 NM_001270425 /// NM_003618 0000185 // activation of MAPKKK activity // not recorded /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 218312_s_at NM_023926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023926.1 /DEF=Homo sapiens hypothetical protein FLJ12895 (FLJ12895), mRNA. /FEA=mRNA /GEN=FLJ12895 /PROD=hypothetical protein FLJ12895 /DB_XREF=gi:12965194 /UG=Hs.235390 hypothetical protein FLJ12895 /FL=gb:NM_023926.1 NM_023926 zinc finger and SCAN domain containing 18 ZSCAN18 65982 NM_001145542 /// NM_001145543 /// NM_001145544 /// NM_023926 /// NR_027135 /// XM_005259174 /// XM_006723335 /// XM_006723336 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218313_s_at NM_017423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017423.1 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) (GALNT7), mRNA. /FEA=mRNA /GEN=GALNT7 /PROD=polypeptide N-acetylgalactosaminyltransferase 7 /DB_XREF=gi:8393408 /UG=Hs.246315 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) /FL=gb:NM_017423.1 NM_017423 polypeptide N-acetylgalactosaminyltransferase 7 GALNT7 51809 NM_017423 /// XM_005263062 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218314_s_at NM_018195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018195.1 /DEF=Homo sapiens hypothetical protein FLJ10726 (FLJ10726), mRNA. /FEA=mRNA /GEN=FLJ10726 /PROD=hypothetical protein FLJ10726 /DB_XREF=gi:8922622 /UG=Hs.268561 hypothetical protein FLJ10726 /FL=gb:NM_018195.1 NM_018195 chromosome 11 open reading frame 57 C11orf57 55216 NM_001082969 /// NM_001082970 /// NM_018195 /// NR_103469 /// XM_006718873 /// XM_006718874 /// XM_006718875 /// XM_006718876 /// XM_006718877 218315_s_at NM_016408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016408.1 /DEF=Homo sapiens CGI-05 protein (LOC51654), mRNA. /FEA=mRNA /GEN=LOC51654 /PROD=hypothetical protein HSPC167 /DB_XREF=gi:7705484 /UG=Hs.306044 CGI-05 protein /FL=gb:AF161516.1 gb:NM_016408.1 NM_016408 CDK5 regulatory subunit associated protein 1 CDK5RAP1 51654 NM_001278167 /// NM_001278168 /// NM_001278169 /// NM_016082 /// NM_016408 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006400 // tRNA modification // inferred from electronic annotation /// 0007420 // brain development // non-traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0043412 // macromolecule modification // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // non-traceable author statement /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 218316_at NM_012460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012460.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 9 (yeast) homolog (TIMM9), mRNA. /FEA=mRNA /GEN=TIMM9 /PROD=translocase of inner mitochondrial membrane 9(yeast) homolog /DB_XREF=gi:6912713 /UG=Hs.323914 translocase of inner mitochondrial membrane 9 (yeast) homolog /FL=gb:AF150100.1 gb:AF152353.1 gb:NM_012460.1 NM_012460 translocase of inner mitochondrial membrane 9 homolog (yeast) TIMM9 26520 NM_012460 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045039 // protein import into mitochondrial inner membrane // inferred from direct assay /// 0045039 // protein import into mitochondrial inner membrane // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042719 // mitochondrial intermembrane space protein transporter complex // inferred from direct assay /// 0042719 // mitochondrial intermembrane space protein transporter complex // traceable author statement 0005215 // transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 218317_x_at NM_024044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024044.1 /DEF=Homo sapiens hypothetical protein MGC5178 (MGC5178), mRNA. /FEA=mRNA /GEN=MGC5178 /PROD=hypothetical protein MGC5178 /DB_XREF=gi:13129003 /UG=Hs.326067 hypothetical protein MGC5178 /FL=gb:BC000754.1 gb:BC000803.1 gb:NM_024044.1 NM_024044 structure-specific endonuclease subunit SLX1-like /// SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) /// SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) LOC101929864 /// SLX1A /// SLX1B 79008 /// 548593 /// 101929864 NM_001014999 /// NM_001015000 /// NM_024044 /// NM_178044 /// XM_006726622 /// XM_006726623 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010792 // DNA double-strand break processing involved in repair via single-strand annealing // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0033557 // Slx1-Slx4 complex // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218318_s_at NM_016231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016231.1 /DEF=Homo sapiens nemo-like kinase (LOC51701), mRNA. /FEA=mRNA /GEN=LOC51701 /PROD=nemo-like kinase /DB_XREF=gi:7706444 /UG=Hs.3532 nemo-like kinase /FL=gb:AF180819.1 gb:AF197898.1 gb:NM_016231.1 NM_016231 nemo-like kinase NLK 51701 NM_016231 /// XM_005257988 0000165 // MAPK cascade // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0033136 // serine phosphorylation of STAT3 protein // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218319_at NM_020651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020651.2 /DEF=Homo sapiens pellino (Drosophila) homolog 1 (PELI1), mRNA. /FEA=mRNA /GEN=PELI1 /PROD=pellino protein /DB_XREF=gi:11037062 /UG=Hs.7886 pellino (Drosophila) homolog 1 /FL=gb:AF302505.1 gb:AF300987.1 gb:NM_020651.2 NM_020651 pellino E3 ubiquitin protein ligase 1 PELI1 57162 NM_020651 /// XM_005264436 /// XM_005264437 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034141 // positive regulation of toll-like receptor 3 signaling pathway // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from electronic annotation /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043331 // response to dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 218320_s_at NM_019056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019056.1 /DEF=Homo sapiens similar to mouse neuronal protein 15.6 (FLJ20494), mRNA. /FEA=mRNA /GEN=FLJ20494 /PROD=similar to mouse neuronal protein 15.6 /DB_XREF=gi:9506682 /UG=Hs.111497 similar to mouse neuronal protein 15.6 /FL=gb:NM_019056.1 NM_019056 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa NDUFB11 54539 NM_001135998 /// NM_019056 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 218321_x_at NM_016086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016086.1 /DEF=Homo sapiens map kinase phosphatase-like protein MK-STYX (LOC51657), mRNA. /FEA=mRNA /GEN=LOC51657 /PROD=map kinase phosphatase-like protein MK-STYX /DB_XREF=gi:7706362 /UG=Hs.11615 map kinase phosphatase-like protein MK-STYX /FL=gb:AF069762.1 gb:NM_016086.1 NM_016086 serine/threonine/tyrosine interacting-like 1 STYXL1 51657 NM_016086 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218322_s_at NM_016234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016234.2 /DEF=Homo sapiens long-chain fatty acid coenzyme A ligase 5 (FACL5), mRNA. /FEA=mRNA /GEN=FACL5 /PROD=long-chain fatty acid coenzyme A ligase 5 /DB_XREF=gi:12669912 /UG=Hs.11638 long-chain fatty acid coenzyme A ligase 5 /FL=gb:NM_016234.2 gb:AB033899.1 NM_016234 acyl-CoA synthetase long-chain family member 5 ACSL5 51703 NM_016234 /// NM_203379 /// NM_203380 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 218323_at NM_018307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018307.1 /DEF=Homo sapiens hypothetical protein FLJ11040 (FLJ11040), mRNA. /FEA=mRNA /GEN=FLJ11040 /PROD=hypothetical protein FLJ11040 /DB_XREF=gi:8922837 /UG=Hs.14202 hypothetical protein FLJ11040 /FL=gb:NM_018307.1 NM_018307 ras homolog family member T1 RHOT1 55288 NM_001033566 /// NM_001033567 /// NM_001033568 /// NM_001288754 /// NM_001288755 /// NM_001288758 /// NM_018307 /// NR_110083 /// XM_005257996 /// XM_006721968 /// XM_006721969 /// XM_006721970 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from mutant phenotype /// 0047497 // mitochondrion transport along microtubule // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218324_s_at NM_023071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023071.1 /DEF=Homo sapiens hypothetical protein FLJ13117 (FLJ13117), mRNA. /FEA=mRNA /GEN=FLJ13117 /PROD=hypothetical protein FLJ13117 /DB_XREF=gi:12751480 /UG=Hs.152982 hypothetical protein FLJ13117 /FL=gb:NM_023071.1 NM_023071 spermatogenesis associated, serine-rich 2 SPATS2 65244 NM_001293285 /// NM_001293286 /// NM_023071 /// NR_120663 /// XR_429112 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218325_s_at NM_022105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022105.1 /DEF=Homo sapiens death associated transcription factor 1 (DATF1), mRNA. /FEA=mRNA /GEN=DATF1 /PROD=death associated transcription factor 1 /DB_XREF=gi:13378138 /UG=Hs.155313 death associated transcription factor 1 /FL=gb:BC004237.1 gb:NM_022105.1 NM_022105 death inducer-obliterator 1 DIDO1 11083 NM_001193369 /// NM_001193370 /// NM_022105 /// NM_033081 /// NM_080796 /// NM_080797 /// XM_006723684 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218326_s_at NM_018490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018490.1 /DEF=Homo sapiens G protein-coupled receptor 48 (GPR48), mRNA. /FEA=mRNA /GEN=GPR48 /PROD=G protein-coupled receptor 48 /DB_XREF=gi:8923700 /UG=Hs.160271 G protein-coupled receptor 48 /FL=gb:AF257182.1 gb:NM_018490.1 NM_018490 leucine-rich repeat containing G protein-coupled receptor 4 LGR4 55366 NM_018490 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030539 // male genitalia development // inferred from electronic annotation /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046849 // bone remodeling // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity /// 0061290 // canonical Wnt signaling pathway involved in metanephric kidney development // inferred from electronic annotation /// 0072202 // cell differentiation involved in metanephros development // inferred from electronic annotation /// 0072224 // metanephric glomerulus development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016500 // protein-hormone receptor activity // inferred from electronic annotation 218327_s_at NM_004782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004782.1 /DEF=Homo sapiens synaptosomal-associated protein, 29kD (SNAP29), mRNA. /FEA=mRNA /GEN=SNAP29 /PROD=synaptosomal-associated protein, 29kD /DB_XREF=gi:4759153 /UG=Hs.194714 synaptosomal-associated protein, 29kD /FL=gb:AF115436.1 gb:NM_004782.1 NM_004782 synaptosomal-associated protein, 29kDa SNAP29 9342 NM_004782 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005484 // SNAP receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 218328_at NM_016035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016035.1 /DEF=Homo sapiens CGI-92 protein (LOC51117), mRNA. /FEA=mRNA /GEN=LOC51117 /PROD=CGI-92 protein /DB_XREF=gi:7705806 /UG=Hs.20159 CGI-92 protein /FL=gb:AF151850.1 gb:NM_016035.1 NM_016035 coenzyme Q4 COQ4 51117 NM_016035 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 218329_at NM_012406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012406.2 /DEF=Homo sapiens PR domain containing 4 (PRDM4), mRNA. /FEA=mRNA /GEN=PRDM4 /PROD=PR domain containing 4 /DB_XREF=gi:9055315 /UG=Hs.21807 PR domain containing 4 /FL=gb:AF144757.2 gb:NM_012406.2 NM_012406 PR domain containing 4 PRDM4 11108 NM_012406 /// XM_005268593 /// XM_006719205 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218330_s_at NM_018162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018162.1 /DEF=Homo sapiens hypothetical protein FLJ10633 (FLJ10633), mRNA. /FEA=mRNA /GEN=FLJ10633 /PROD=hypothetical protein FLJ10633 /DB_XREF=gi:9506612 /UG=Hs.23467 hypothetical protein FLJ10633 /FL=gb:NM_018162.1 NM_018162 neuron navigator 2 NAV2 89797 NM_001111018 /// NM_001111019 /// NM_001244963 /// NM_145117 /// NM_182964 /// XM_005253214 /// XM_006718364 /// XM_006718365 /// XM_006718366 /// XM_006718367 /// XM_006718368 /// XM_006718369 0003025 // regulation of systemic arterial blood pressure by baroreceptor feedback // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021554 // optic nerve development // inferred from electronic annotation /// 0021563 // glossopharyngeal nerve development // inferred from electronic annotation /// 0021564 // vagus nerve development // inferred from electronic annotation 0005614 // interstitial matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 218331_s_at NM_017782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017782.1 /DEF=Homo sapiens hypothetical protein FLJ20360 (FLJ20360), mRNA. /FEA=mRNA /GEN=FLJ20360 /PROD=hypothetical protein FLJ20360 /DB_XREF=gi:8923334 /UG=Hs.26434 hypothetical protein FLJ20360 /FL=gb:BC001759.1 gb:NM_017782.1 NM_017782 family with sequence similarity 208, member B FAM208B 54906 NM_017782 /// XM_005252474 /// XM_005252475 /// XM_005252476 /// XM_005252477 /// XM_005252478 /// XM_005252480 /// XM_005252481 /// XM_005252482 /// XM_005252483 /// XM_006717452 218332_at NM_018476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018476.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HBEX2 (HBEX2), mRNA. /FEA=mRNA /GEN=HBEX2 /PROD=uncharacterized hypothalamus protein HBEX2 /DB_XREF=gi:8923715 /UG=Hs.283719 uncharacterized hypothalamus protein HBEX2 /FL=gb:AF220189.1 gb:NM_018476.1 gb:AF183416.1 gb:AF237783.1 NM_018476 brain expressed, X-linked 1 BEX1 55859 NM_018476 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction 218333_at NM_016041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016041.1 /DEF=Homo sapiens CGI-101 protein (LOC51009), mRNA. /FEA=mRNA /GEN=LOC51009 /PROD=CGI-101 protein /DB_XREF=gi:7705603 /UG=Hs.286131 CGI-101 protein /FL=gb:AF132289.1 gb:AF151859.1 gb:NM_016041.1 gb:AF242523.1 NM_016041 derlin 2 DERL2 51009 NM_016041 /// XM_005256672 /// XM_006721539 0001967 // suckling behavior // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218334_at NM_025075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025075.1 /DEF=Homo sapiens hypothetical protein FLJ23445 (FLJ23445), mRNA. /FEA=mRNA /GEN=FLJ23445 /PROD=hypothetical protein FLJ23445 /DB_XREF=gi:13376622 /UG=Hs.288151 hypothetical protein FLJ23445 /FL=gb:NM_025075.1 NM_025075 THO complex 7 homolog (Drosophila) THOC7 80145 NM_001285387 /// NM_001285404 /// NM_025075 /// XM_006713339 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218335_x_at NM_024309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024309.1 /DEF=Homo sapiens hypothetical protein MGC4289 (MGC4289), mRNA. /FEA=mRNA /GEN=MGC4289 /PROD=hypothetical protein MGC4289 /DB_XREF=gi:13236543 /UG=Hs.288991 hypothetical protein MGC4289 /FL=gb:BC002740.1 gb:NM_024309.1 NM_024309 TNFAIP3 interacting protein 2 TNIP2 79155 NM_001161527 /// NM_001292016 /// NM_024309 /// XM_005248010 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0023035 // CD40 signaling pathway // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // inferred from sequence or structural similarity /// 0034162 // toll-like receptor 9 signaling pathway // inferred from sequence or structural similarity /// 0043032 // positive regulation of macrophage activation // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050871 // positive regulation of B cell activation // inferred from sequence or structural similarity /// 0070498 // interleukin-1-mediated signaling pathway // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay 218336_at NM_012394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012394.2 /DEF=Homo sapiens prefoldin 2 (PFDN2), mRNA. /FEA=mRNA /GEN=PFDN2 /PROD=prefoldin 2 /DB_XREF=gi:12408674 /UG=Hs.298229 prefoldin 2 /FL=gb:NM_012394.2 gb:AF165883.1 gb:AF117237.1 gb:AF151065.1 NM_012394 prefoldin subunit 2 PFDN2 5202 NM_012394 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016272 // prefoldin complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 218337_at NM_022749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022749.1 /DEF=Homo sapiens hypothetical protein FLJ21801 (FLJ21801), mRNA. /FEA=mRNA /GEN=FLJ21801 /PROD=hypothetical protein FLJ21801 /DB_XREF=gi:12232410 /UG=Hs.299148 hypothetical protein FLJ21801 /FL=gb:NM_022749.1 NM_022749 family with sequence similarity 160, member B2 FAM160B2 64760 NM_022749 /// XM_005273602 /// XM_006716381 /// XM_006716382 /// XM_006716383 /// XM_006716384 /// XM_006716385 /// XR_247128 /// XR_428313 /// XR_428314 218338_at NM_004426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004426.1 /DEF=Homo sapiens early development regulator 1 (homolog of polyhomeotic 1) (EDR1), mRNA. /FEA=mRNA /GEN=EDR1 /PROD=early development regulator 1 /DB_XREF=gi:11038623 /UG=Hs.305985 early development regulator 1 (homolog of polyhomeotic 1) /FL=gb:NM_004426.1 NM_004426 polyhomeotic homolog 1 (Drosophila) PHC1 1911 NM_004426 /// XM_005253334 /// XM_005253336 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218339_at NM_014180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014180.1 /DEF=Homo sapiens HSPC158 protein (HSPC158), mRNA. /FEA=mRNA /GEN=HSPC158 /PROD=HSPC158 protein /DB_XREF=gi:7661815 /UG=Hs.41007 HSPC158 protein /FL=gb:AF161507.1 gb:NM_014180.1 NM_014180 mitochondrial ribosomal protein L22 MRPL22 29093 NM_001014990 /// NM_014180 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218340_s_at NM_018227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018227.1 /DEF=Homo sapiens hypothetical protein FLJ10808 (FLJ10808), mRNA. /FEA=mRNA /GEN=FLJ10808 /PROD=hypothetical protein FLJ10808 /DB_XREF=gi:8922683 /UG=Hs.59838 hypothetical protein FLJ10808 /FL=gb:AB014773.1 gb:NM_018227.1 NM_018227 ubiquitin-like modifier activating enzyme 6 UBA6 55236 NM_018227 /// XM_006714253 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019780 // FAT10 activating enzyme activity // inferred from mutant phenotype 218341_at NM_024664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024664.1 /DEF=Homo sapiens hypothetical protein FLJ11838 (FLJ11838), mRNA. /FEA=mRNA /GEN=FLJ11838 /PROD=hypothetical protein FLJ11838 /DB_XREF=gi:13375918 /UG=Hs.72531 hypothetical protein FLJ11838 /FL=gb:NM_024664.1 NM_024664 phosphopantothenoylcysteine synthetase PPCS 79717 NM_001077447 /// NM_001287506 /// NM_001287507 /// NM_001287508 /// NM_001287509 /// NM_001287510 /// NM_001287511 /// NM_024664 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004632 // phosphopantothenate--cysteine ligase activity // inferred from direct assay /// 0004632 // phosphopantothenate--cysteine ligase activity // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation 218342_s_at NM_024896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024896.1 /DEF=Homo sapiens hypothetical protein FLJ23309 (FLJ23309), mRNA. /FEA=mRNA /GEN=FLJ23309 /PROD=hypothetical protein FLJ23309 /DB_XREF=gi:13487920 /UG=Hs.87128 hypothetical protein FLJ23309 /FL=gb:NM_024896.1 NM_024896 endoplasmic reticulum metallopeptidase 1 ERMP1 79956 NM_024896 /// XM_005251587 /// XR_428431 /// XR_428432 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218343_s_at NM_012086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012086.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 3 (102kD) (GTF3C3), mRNA. /FEA=mRNA /GEN=GTF3C3 /PROD=general transcription factor IIIC, polypeptide 3(102kD) /DB_XREF=gi:6912397 /UG=Hs.90847 general transcription factor IIIC, polypeptide 3 (102kD) /FL=gb:AF133123.1 gb:NM_012086.1 NM_012086 general transcription factor IIIC, polypeptide 3, 102kDa GTF3C3 9330 NM_001206774 /// NM_012086 /// XM_005246965 0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 218344_s_at NM_018254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018254.1 /DEF=Homo sapiens hypothetical protein FLJ10876 (FLJ10876), mRNA. /FEA=mRNA /GEN=FLJ10876 /PROD=hypothetical protein FLJ10876 /DB_XREF=gi:8922732 /UG=Hs.94042 hypothetical protein FLJ10876 /FL=gb:NM_018254.1 NM_018254 REST corepressor 3 RCOR3 55758 NM_001136223 /// NM_001136224 /// NM_001136225 /// NM_018254 /// XM_005273191 /// XM_005273192 /// XM_006711442 /// XM_006711443 /// XM_006711444 /// XR_426789 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218345_at NM_018487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018487.1 /DEF=Homo sapiens hepatocellular carcinoma-associated antigen 112 (HCA112), mRNA. /FEA=mRNA /GEN=HCA112 /PROD=hepatocellular carcinoma-associated antigen 112 /DB_XREF=gi:8923717 /UG=Hs.12126 hepatocellular carcinoma-associated antigen 112 /FL=gb:AF258340.1 gb:NM_018487.1 NM_018487 transmembrane protein 176A TMEM176A 55365 NM_018487 2001199 // negative regulation of dendritic cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218346_s_at NM_014454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014454.1 /DEF=Homo sapiens p53 regulated PA26 nuclear protein (PA26), mRNA. /FEA=mRNA /GEN=PA26 /PROD=p53 regulated PA26 nuclear protein /DB_XREF=gi:7657436 /UG=Hs.14125 p53 regulated PA26 nuclear protein /FL=gb:AF033122.1 gb:NM_014454.1 NM_014454 sestrin 1 SESN1 27244 NM_001199933 /// NM_001199934 /// NM_014454 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 1901031 // regulation of response to reactive oxygen species // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 218347_at NM_018264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018264.1 /DEF=Homo sapiens hypothetical protein FLJ10900 (FLJ10900), mRNA. /FEA=mRNA /GEN=FLJ10900 /PROD=hypothetical protein FLJ10900 /DB_XREF=gi:8922751 /UG=Hs.16277 hypothetical protein FLJ10900 /FL=gb:NM_018264.1 NM_018264 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) TYW1 55253 NM_018264 /// XR_242254 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 218348_s_at NM_014153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014153.1 /DEF=Homo sapiens HSPC055 protein (HSPC055), mRNA. /FEA=mRNA /GEN=HSPC055 /PROD=HSPC055 protein /DB_XREF=gi:7661761 /UG=Hs.179898 HSPC055 protein /FL=gb:AF161540.1 gb:NM_014153.1 NM_014153 zinc finger CCCH-type containing 7A ZC3H7A 29066 NM_014153 /// XM_005255270 /// XM_005255272 /// XM_005255273 /// XM_006720877 0005634 // nucleus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218349_s_at NM_017975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017975.1 /DEF=Homo sapiens hypothetical protein FLJ10036 (FLJ10036), mRNA. /FEA=mRNA /GEN=FLJ10036 /PROD=hypothetical protein FLJ10036 /DB_XREF=gi:8922195 /UG=Hs.21331 hypothetical protein FLJ10036 /FL=gb:NM_017975.1 NM_017975 zwilch kinetochore protein ZWILCH 55055 NM_001287821 /// NM_001287822 /// NM_001287823 /// NM_017975 /// NR_003105 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 218350_s_at NM_015895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015895.1 /DEF=Homo sapiens geminin (LOC51053), mRNA. /FEA=mRNA /GEN=LOC51053 /PROD=geminin /DB_XREF=gi:7705681 /UG=Hs.234896 geminin /FL=gb:AF067855.1 gb:NM_015895.1 NM_015895 geminin, DNA replication inhibitor GMNN 51053 NM_001251989 /// NM_001251990 /// NM_001251991 /// NM_015895 /// XM_005249159 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 218351_at NM_017845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017845.1 /DEF=Homo sapiens hypothetical protein FLJ20502 (FLJ20502), mRNA. /FEA=mRNA /GEN=FLJ20502 /PROD=hypothetical protein FLJ20502 /DB_XREF=gi:8923457 /UG=Hs.23956 hypothetical protein FLJ20502 /FL=gb:AF182421.1 gb:NM_017845.1 NM_017845 COMM domain containing 8 COMMD8 54951 NM_017845 /// XM_006714019 0005515 // protein binding // inferred from physical interaction 218352_at NM_018191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018191.1 /DEF=Homo sapiens hypothetical protein FLJ10716 (FLJ10716), mRNA. /FEA=mRNA /GEN=FLJ10716 /PROD=hypothetical protein FLJ10716 /DB_XREF=gi:8922616 /UG=Hs.24129 hypothetical protein FLJ10716 /FL=gb:NM_018191.1 NM_018191 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 RCBTB1 55213 NM_018191 /// XM_005266441 /// XM_006719843 /// XR_245392 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218353_at NM_025226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025226.1 /DEF=Homo sapiens MSTP032 protein (MSTP032), mRNA. /FEA=mRNA /GEN=MSTP032 /PROD=MSTP032 protein /DB_XREF=gi:13376831 /UG=Hs.274368 MSTP032 protein /FL=gb:AF113212.1 gb:NM_025226.1 NM_025226 regulator of G-protein signaling 5 RGS5 8490 NM_001195303 /// NM_001254748 /// NM_001254749 /// NM_003617 /// NM_025226 /// NR_045630 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded 218354_at NM_016209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016209.1 /DEF=Homo sapiens unknown (LOC51693), mRNA. /FEA=mRNA /GEN=LOC51693 /PROD=unknown /DB_XREF=gi:7706428 /UG=Hs.27445 unknown /FL=gb:AF089106.1 gb:AF161524.1 gb:NM_016209.1 NM_016209 trafficking protein particle complex 2-like TRAPPC2L 51693 NM_016209 /// XM_005256313 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218355_at NM_012310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012310.2 /DEF=Homo sapiens kinesin family member 4A (KIF4A), mRNA. /FEA=mRNA /GEN=KIF4A /PROD=kinesin family member 4 /DB_XREF=gi:7305204 /UG=Hs.279766 kinesin family member 4A /FL=gb:AF179308.1 gb:AF071592.2 gb:NM_012310.2 NM_012310 kinesin family member 4A KIF4A 24137 NM_012310 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 218356_at NM_013393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013393.1 /DEF=Homo sapiens cell division protein FtsJ (FJH1), mRNA. /FEA=mRNA /GEN=FJH1 /PROD=cell division protein FtsJ /DB_XREF=gi:7019376 /UG=Hs.279877 cell division protein FtsJ /FL=gb:AF093415.1 gb:NM_013393.1 NM_013393 FtsJ RNA methyltransferase homolog 2 (E. coli) FTSJ2 29960 NM_013393 /// NM_177442 0001510 // RNA methylation // inferred from electronic annotation /// 0006364 // rRNA processing // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0031167 // rRNA methylation // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008650 // rRNA (uridine-2'-O-)-methyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 218357_s_at NM_012459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012459.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 8 (yeast) homolog B (TIMM8B), mRNA. /FEA=mRNA /GEN=TIMM8B /PROD=translocase of inner mitochondrial membrane 8(yeast) homolog B /DB_XREF=gi:6912711 /UG=Hs.279915 translocase of inner mitochondrial membrane 8 (yeast) homolog B /FL=gb:AF150087.1 gb:AF152350.1 gb:NM_012459.1 NM_012459 translocase of inner mitochondrial membrane 8 homolog B (yeast) TIMM8B 26521 NM_012459 /// NR_028383 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072321 // chaperone-mediated protein transport // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042719 // mitochondrial intermembrane space protein transporter complex // traceable author statement 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218358_at NM_024324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024324.1 /DEF=Homo sapiens hypothetical protein MGC11256 (MGC11256), mRNA. /FEA=mRNA /GEN=MGC11256 /PROD=hypothetical protein MGC11256 /DB_XREF=gi:13236568 /UG=Hs.28029 hypothetical protein MGC11256 /FL=gb:BC002894.1 gb:NM_024324.1 NM_024324 cysteine-rich with EGF-like domains 2 CRELD2 79174 NM_001135101 /// NM_001284317 /// NM_001284318 /// NM_024324 /// NR_104295 /// XM_005261737 /// XM_005261738 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218359_at NM_024958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024958.1 /DEF=Homo sapiens hypothetical protein FLJ23329 (FLJ23329), mRNA. /FEA=mRNA /GEN=FLJ23329 /PROD=hypothetical protein FLJ23329 /DB_XREF=gi:13376446 /UG=Hs.286128 hypothetical protein FLJ23329 /FL=gb:AL136915.1 gb:BC001963.1 gb:NM_024958.1 NM_024958 neurensin 2 NRSN2 80023 NM_024958 /// XM_005260831 /// XM_005260834 /// XM_006723629 /// XM_006723630 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation 218360_at NM_020673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020673.1 /DEF=Homo sapiens RAB22A, member RAS oncogene family (RAB22A), mRNA. /FEA=mRNA /GEN=RAB22A /PROD=RAB22A, member RAS oncogene family /DB_XREF=gi:10190713 /UG=Hs.288968 RAB22A, member RAS oncogene family /FL=gb:NM_020673.1 gb:AF091034.2 NM_020673 RAB22A, member RAS oncogene family RAB22A 57403 NM_020673 /// XM_005260469 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from expression pattern /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 218361_at NM_018178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018178.1 /DEF=Homo sapiens hypothetical protein FLJ10687 (FLJ10687), mRNA. /FEA=mRNA /GEN=FLJ10687 /PROD=hypothetical protein FLJ10687 /DB_XREF=gi:8922588 /UG=Hs.29379 hypothetical protein FLJ10687 /FL=gb:NM_018178.1 NM_018178 golgi phosphoprotein 3-like GOLPH3L 55204 NM_018178 /// XM_006711428 0007030 // Golgi organization // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype 0000139 // Golgi membrane // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred by curator 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay 218362_s_at NM_014953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014953.1 /DEF=Homo sapiens KIAA1008 protein (KIAA1008), mRNA. /FEA=mRNA /GEN=KIAA1008 /PROD=KIAA1008 protein /DB_XREF=gi:7662443 /UG=Hs.323346 KIAA1008 protein /FL=gb:AB023225.1 gb:NM_014953.1 NM_014953 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease DIS3 22894 NM_001128226 /// NM_014953 /// XM_005266294 /// XM_006719778 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016075 // rRNA catabolic process // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071034 // CUT catabolic process // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from mutant phenotype 0000176 // nuclear exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from mutant phenotype /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 218363_at NM_018199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018199.1 /DEF=Homo sapiens hypothetical protein FLJ10738 (FLJ10738), mRNA. /FEA=mRNA /GEN=FLJ10738 /PROD=hypothetical protein FLJ10738 /DB_XREF=gi:8922630 /UG=Hs.5457 hypothetical protein FLJ10738 /FL=gb:BC001962.1 gb:NM_018199.1 NM_018199 exonuclease 3'-5' domain containing 2 EXD2 55218 NM_001193360 /// NM_001193361 /// NM_001193362 /// NM_001193363 /// NM_018199 /// NR_034164 /// NR_034165 /// XM_005267817 /// XM_005267818 /// XM_006720190 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008408 // 3'-5' exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218364_at NM_017724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017724.1 /DEF=Homo sapiens leucine rich repeat (in FLII) interacting protein 2 (LRRFIP2), mRNA. /FEA=mRNA /GEN=LRRFIP2 /PROD=leucine rich repeat (in FLII) interactingprotein 2 /DB_XREF=gi:8923223 /UG=Hs.57672 leucine rich repeat (in FLII) interacting protein 2 /FL=gb:NM_017724.1 NM_017724 leucine rich repeat (in FLII) interacting protein 2 LRRFIP2 9209 NM_001134369 /// NM_001282691 /// NM_006309 /// NM_017724 /// XM_005265538 /// XM_005265539 /// XM_005265540 /// XM_005265550 /// XM_005265551 /// XM_005265553 /// XM_005265554 /// XM_005265555 /// XM_005265556 /// XM_005265557 /// XM_006713385 /// XM_006713386 /// XM_006713387 /// XM_006713388 /// XM_006713389 /// XM_006713390 /// XM_006713391 /// XM_006713392 /// XM_006713393 /// XM_006713394 /// XM_006713395 /// XM_006713396 /// XM_006713397 /// XM_006713398 /// XM_006713399 /// XM_006713400 /// XM_006713401 /// XM_006713402 /// XM_006713403 /// XM_006713404 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 218365_s_at AI765051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI765051 /FEA=EST /DB_XREF=gi:5231560 /DB_XREF=est:wh56e09.x1 /CLONE=IMAGE:2384776 /UG=Hs.59346 hypothetical protein FLJ10514 /FL=gb:NM_018122.1 AI765051 aspartyl-tRNA synthetase 2, mitochondrial DARS2 55157 NM_018122 /// XM_005245299 /// XM_006711426 /// XM_006711427 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from direct assay /// 0070145 // mitochondrial asparaginyl-tRNA aminoacylation // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050560 // aspartate-tRNA(Asn) ligase activity // inferred from direct assay 218366_x_at NM_022734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022734.1 /DEF=Homo sapiens hypothetical protein FLJ20859 (FLJ20859), mRNA. /FEA=mRNA /GEN=FLJ20859 /PROD=hypothetical protein FLJ20859 /DB_XREF=gi:12232388 /UG=Hs.6311 hypothetical protein FLJ20859 /FL=gb:NM_022734.1 NM_022734 methyltransferase like 17 METTL17 64745 NM_001029991 /// NM_001029992 /// NM_022734 /// XM_006720235 /// XM_006720236 /// XM_006720237 0006412 // translation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218367_x_at NM_012475 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012475.1 /DEF=Homo sapiens ubiquitin specific protease 21 (USP21), mRNA. /FEA=mRNA /GEN=USP21 /PROD=ubiquitin specific protease 23 /DB_XREF=gi:6912741 /UG=Hs.8015 ubiquitin specific protease 21 /FL=gb:BC003130.1 gb:AF177758.1 gb:NM_012475.1 gb:AF233442.1 gb:NM_016572.1 NM_012475 ubiquitin specific peptidase 21 USP21 27005 NM_001014443 /// NM_012475 /// XM_006711273 /// XM_006711274 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from mutant phenotype /// 0008234 // cysteine-type peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218368_s_at NM_016639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016639.1 /DEF=Homo sapiens type I transmembrane protein Fn14 (FN14), mRNA. /FEA=mRNA /GEN=FN14 /PROD=type I transmembrane protein Fn14 /DB_XREF=gi:7706185 /UG=Hs.10086 type I transmembrane protein Fn14 /FL=gb:BC002718.1 gb:AB035480.1 gb:NM_016639.1 gb:AF191148.1 NM_016639 tumor necrosis factor receptor superfamily, member 12A TNFRSF12A 51330 NM_016639 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006931 // substrate-dependent cell migration, cell attachment to substrate // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0061041 // regulation of wound healing // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218369_s_at NM_016046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016046.1 /DEF=Homo sapiens homolog of yeast exosomal core protein CSL4 (CSL4), mRNA. /FEA=mRNA /GEN=CSL4 /PROD=homolog of yeast exosomal core protein CSL4 /DB_XREF=gi:7705611 /UG=Hs.14415 homolog of yeast exosomal core protein CSL4 /FL=gb:AF151866.1 gb:NM_016046.1 NM_016046 exosome component 1 EXOSC1 51013 NM_016046 /// XR_246092 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0000178 // exosome (RNase complex) // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // non-traceable author statement /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218370_s_at NM_022753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022753.1 /DEF=Homo sapiens hypothetical protein FLJ12903 (FLJ12903), mRNA. /FEA=mRNA /GEN=FLJ12903 /PROD=hypothetical protein FLJ12903 /DB_XREF=gi:12232418 /UG=Hs.14928 hypothetical protein FLJ12903 /FL=gb:NM_022753.1 NM_022753 S100P binding protein S100PBP 64766 NM_001017406 /// NM_001256121 /// NM_022753 /// XM_006710818 /// XM_006710819 /// XM_006710820 0005634 // nucleus // inferred from direct assay 0048306 // calcium-dependent protein binding // inferred from physical interaction 218371_s_at NM_018282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018282.1 /DEF=Homo sapiens hypothetical protein FLJ10955 (FLJ10955), mRNA. /FEA=mRNA /GEN=FLJ10955 /PROD=hypothetical protein FLJ10955 /DB_XREF=gi:8922788 /UG=Hs.16364 hypothetical protein FLJ10955 /FL=gb:NM_018282.1 NM_018282 paraspeckle component 1 PSPC1 55269 NM_001042414 /// NR_003272 /// NR_044998 /// XM_006719844 /// XM_006719845 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218372_at NM_018019 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018019.1 /DEF=Homo sapiens hypothetical protein FLJ10193 (FLJ10193), mRNA. /FEA=mRNA /GEN=FLJ10193 /PROD=hypothetical protein FLJ10193 /DB_XREF=gi:8922272 /UG=Hs.235195 hypothetical protein FLJ10193 /FL=gb:BC000647.1 gb:NM_018019.1 NM_018019 mediator complex subunit 9 MED9 55090 NM_018019 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218373_at NM_022476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022476.1 /DEF=Homo sapiens hypothetical protein FLJ13258 similar to fused toes (FLJ13258), mRNA. /FEA=mRNA /GEN=FLJ13258 /PROD=hypothetical protein FLJ13258 similar to fusedtoes /DB_XREF=gi:11968026 /UG=Hs.288929 hypothetical protein FLJ13258 similar to fused toes /FL=gb:NM_022476.1 NM_022476 AKT interacting protein AKTIP 64400 NM_001012398 /// NM_022476 /// XM_005256094 /// XM_005256095 /// XM_005256096 /// XM_005256097 /// XM_005256098 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0070695 // FHF complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // non-traceable author statement 218374_s_at NM_020374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020374.1 /DEF=Homo sapiens chromosome 12 open reading frame 4 (C12ORF4), mRNA. /FEA=mRNA /GEN=C12ORF4 /PROD=chromosome 12 open reading frame 4 /DB_XREF=gi:9966846 /UG=Hs.296198 chromosome 12 open reading frame 4 /FL=gb:NM_020374.1 NM_020374 chromosome 12 open reading frame 4 C12orf4 57102 NM_020374 /// XM_005253716 /// XM_006718992 218375_at NM_024047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024047.1 /DEF=Homo sapiens hypothetical protein MGC3037 (MGC3037), mRNA. /FEA=mRNA /GEN=MGC3037 /PROD=hypothetical protein MGC3037 /DB_XREF=gi:13129009 /UG=Hs.301789 hypothetical protein MGC3037 /FL=gb:BC000542.1 gb:NM_024047.1 NM_024047 nudix (nucleoside diphosphate linked moiety X)-type motif 9 NUDT9 53343 NM_001248011 /// NM_024047 /// NM_198038 0006812 // cation transport // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0034656 // nucleobase-containing small molecule catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046032 // ADP catabolic process // inferred from electronic annotation /// 0046709 // IDP catabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005227 // calcium activated cation channel activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019144 // ADP-sugar diphosphatase activity // non-traceable author statement /// 0043262 // adenosine-diphosphatase activity // inferred from electronic annotation /// 0047631 // ADP-ribose diphosphatase activity // not recorded 218376_s_at NM_022765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022765.1 /DEF=Homo sapiens hypothetical protein FLJ11937 (FLJ11937), mRNA. /FEA=mRNA /GEN=FLJ11937 /PROD=hypothetical protein FLJ11937 /DB_XREF=gi:12232438 /UG=Hs.33476 hypothetical protein FLJ11937 /FL=gb:NM_022765.1 NM_022765 microtubule associated monooxygenase, calponin and LIM domain containing 1 MICAL1 64780 NM_001159291 /// NM_001286613 /// NM_022765 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0019417 // sulfur oxidation // inferred from sequence or structural similarity /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // non-traceable author statement 0003779 // actin binding // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay 218377_s_at NM_016940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016940.1 /DEF=Homo sapiens chromosome 21 open reading frame 6 (C21ORF6), mRNA. /FEA=mRNA /GEN=C21ORF6 /PROD=chromosome 21 open reading frame 6 /DB_XREF=gi:8393017 /UG=Hs.34136 chromosome 21 open reading frame 6 /FL=gb:AF212232.1 gb:NM_016940.1 NM_016940 RWD domain containing 2B RWDD2B 10069 NM_016940 /// XM_006723952 0005515 // protein binding // inferred from electronic annotation 218378_s_at NM_024653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024653.1 /DEF=Homo sapiens hypothetical protein FLJ13902 (FLJ13902), mRNA. /FEA=mRNA /GEN=FLJ13902 /PROD=hypothetical protein FLJ13902 /DB_XREF=gi:13375900 /UG=Hs.58127 hypothetical protein FLJ13902 /FL=gb:NM_024653.1 NM_024653 uncharacterized LOC100289561 /// LOC100289561-PRKRIP1 readthrough /// PRKR interacting protein 1 (IL11 inducible) LOC100289561 /// LOC100630923 /// PRKRIP1 79706 /// 100289561 /// 100630923 NM_001242713 /// NM_024653 /// NR_038967 0003014 // renal system process // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0042326 // negative regulation of phosphorylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from sequence or structural similarity /// 0004860 // protein kinase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 218379_at NM_016090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016090.1 /DEF=Homo sapiens RNA binding motif protein 7 (RBM7), mRNA. /FEA=mRNA /GEN=RBM7 /PROD=RNA binding motif protein 7 /DB_XREF=gi:9994184 /UG=Hs.5887 RNA binding motif protein 7 /FL=gb:AF156098.1 gb:NM_016090.1 NM_016090 RNA binding motif protein 7 RBM7 10179 NM_001286045 /// NM_001286046 /// NM_001286047 /// NM_001286048 /// NM_016090 0007126 // meiotic nuclear division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218380_at NM_021730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021730.1 /DEF=Homo sapiens hypothetical protein PP1044 (PP1044), mRNA. /FEA=mRNA /GEN=PP1044 /PROD=hypothetical protein PP1044 /DB_XREF=gi:11119423 /UG=Hs.7212 hypothetical protein PP1044 /FL=gb:NM_021730.1 NM_021730 uncharacterized LOC728392 LOC728392 728392 NM_001162371 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051402 // neuron apoptotic process // inferred from direct assay 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072558 // NLRP1 inflammasome complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 218381_s_at NM_007279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_007279.1 /DEF=Homo sapiens U2 small nuclear ribonucleoprotein auxiliary factor (65kD) (U2AF65), mRNA. /FEA=mRNA /GEN=U2AF65 /PROD=U2 small nuclear ribonucleoprotein auxiliaryfactor (65kD) /DB_XREF=gi:6005925 /UG=Hs.7655 U2 small nuclear ribonucleoprotein auxiliary factor (65kD) /FL=gb:NM_007279.1 NM_007279 U2 small nuclear RNA auxiliary factor 2 U2AF2 11338 NM_001012478 /// NM_007279 /// XM_006722994 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from electronic annotation 218382_s_at NM_007279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007279.1 /DEF=Homo sapiens U2 small nuclear ribonucleoprotein auxiliary factor (65kD) (U2AF65), mRNA. /FEA=mRNA /GEN=U2AF65 /PROD=U2 small nuclear ribonucleoprotein auxiliaryfactor (65kD) /DB_XREF=gi:6005925 /UG=Hs.7655 U2 small nuclear ribonucleoprotein auxiliary factor (65kD) /FL=gb:NM_007279.1 NM_007279 U2 small nuclear RNA auxiliary factor 2 U2AF2 11338 NM_001012478 /// NM_007279 /// XM_006722994 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from electronic annotation 218383_at NM_017815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017815.1 /DEF=Homo sapiens hypothetical protein FLJ20424 (FLJ20424), mRNA. /FEA=mRNA /GEN=FLJ20424 /PROD=hypothetical protein FLJ20424 /DB_XREF=gi:8923395 /UG=Hs.8886 hypothetical protein FLJ20424 /FL=gb:BC002554.1 gb:BC001916.1 gb:NM_017815.1 NM_017815 HAUS augmin-like complex, subunit 4 /// microRNA 4707 HAUS4 /// MIR4707 54930 /// 100616424 NM_001166269 /// NM_001166270 /// NM_017815 /// NR_039856 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 218384_at NM_014316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014316.1 /DEF=Homo sapiens calcium-regulated heat-stable protein (24kD) (CRHSP-24), mRNA. /FEA=mRNA /GEN=CRHSP-24 /PROD=calcium-regulated heat-stable protein (24kD) /DB_XREF=gi:7656994 /UG=Hs.92198 calcium-regulated heat-stable protein (24kD) /FL=gb:BC001333.1 gb:BC003366.1 gb:AF115345.1 gb:NM_014316.1 NM_014316 calcium regulated heat stable protein 1, 24kDa CARHSP1 23589 NM_001042476 /// NM_001278260 /// NM_001278261 /// NM_001278262 /// NM_001278263 /// NM_001278264 /// NM_001278265 /// NM_001278266 /// NM_014316 /// XM_005255228 /// XM_005255229 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from sequence or structural similarity 0000177 // cytoplasmic exosome (RNase complex) // inferred from sequence or structural similarity /// 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0043186 // P granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0019902 // phosphatase binding // non-traceable author statement 218385_at NM_018135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018135.1 /DEF=Homo sapiens hypothetical protein FLJ10548 (FLJ10548), mRNA. /FEA=mRNA /GEN=FLJ10548 /PROD=hypothetical protein FLJ10548 /DB_XREF=gi:8922510 /UG=Hs.9622 hypothetical protein FLJ10548 /FL=gb:NM_018135.1 NM_018135 mitochondrial ribosomal protein S18A MRPS18A 55168 NM_001193343 /// NM_018135 /// XM_006715134 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 218386_x_at NM_006447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006447.1 /DEF=Homo sapiens ubiquitin specific protease 16 (USP16), mRNA. /FEA=mRNA /GEN=USP16 /PROD=ubiquitin specific protease 16 /DB_XREF=gi:5454155 /UG=Hs.99819 ubiquitin specific protease 16 /FL=gb:AF113219.1 gb:AF126736.1 gb:NM_006447.1 NM_006447 ubiquitin specific peptidase 16 USP16 10600 NM_001001992 /// NM_001032410 /// NM_006447 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045901 // positive regulation of translational elongation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051301 // cell division // inferred from electronic annotation /// 0070537 // histone H2A K63-linked deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218387_s_at NM_012088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012088.1 /DEF=Homo sapiens 6-phosphogluconolactonase (PGLS), mRNA. /FEA=mRNA /GEN=PGLS /PROD=6-phosphogluconolactonase /DB_XREF=gi:6912585 /UG=Hs.100071 6-phosphogluconolactonase /FL=gb:NM_012088.1 NM_012088 6-phosphogluconolactonase PGLS 25796 NM_012088 /// XM_005259849 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017057 // 6-phosphogluconolactonase activity // inferred from direct assay /// 0048029 // monosaccharide binding // inferred from electronic annotation 218388_at NM_012088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012088.1 /DEF=Homo sapiens 6-phosphogluconolactonase (PGLS), mRNA. /FEA=mRNA /GEN=PGLS /PROD=6-phosphogluconolactonase /DB_XREF=gi:6912585 /UG=Hs.100071 6-phosphogluconolactonase /FL=gb:NM_012088.1 NM_012088 6-phosphogluconolactonase PGLS 25796 NM_012088 /// XM_005259849 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017057 // 6-phosphogluconolactonase activity // inferred from direct assay /// 0048029 // monosaccharide binding // inferred from electronic annotation 218389_s_at NM_016022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016022.1 /DEF=Homo sapiens CGI-78 protein (LOC51107), mRNA. /FEA=mRNA /GEN=LOC51107 /PROD=CGI-78 protein /DB_XREF=gi:7705786 /UG=Hs.108408 CGI-78 protein /FL=gb:AF151835.1 gb:NM_016022.1 NM_016022 APH1A gamma secretase subunit APH1A 51107 NM_001077628 /// NM_001243771 /// NM_001243772 /// NM_016022 /// NR_045033 /// NR_045034 /// NR_045035 /// XM_006711362 0001656 // metanephros development // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // inferred from mutant phenotype /// 0007220 // Notch receptor processing // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // inferred from mutant phenotype /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0042987 // amyloid precursor protein catabolic process // inferred from mutant phenotype /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218390_s_at NM_022063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022063.1 /DEF=Homo sapiens hypothetical protein FLJ13188 (FLJ13188), mRNA. /FEA=mRNA /GEN=FLJ13188 /PROD=hypothetical protein FLJ13188 /DB_XREF=gi:11545770 /UG=Hs.11859 hypothetical protein FLJ13188 /FL=gb:NM_022063.1 NM_022063 family with sequence similarity 204, member A FAM204A 63877 NM_001134672 /// NM_022063 /// XM_005270024 /// XM_006717939 /// XR_428712 218391_at NM_007241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007241.1 /DEF=Homo sapiens EAP30 subunit of ELL complex (EAP30), mRNA. /FEA=mRNA /GEN=EAP30 /PROD=EAP30 subunit of ELL complex /DB_XREF=gi:6005754 /UG=Hs.132785 EAP30 subunit of ELL complex /FL=gb:AF156102.1 gb:NM_007241.1 NM_007241 SNF8, ESCRT-II complex subunit SNF8 11267 NM_007241 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 218392_x_at NM_022754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022754.1 /DEF=Homo sapiens hypothetical protein FLJ12876 (FLJ12876), mRNA. /FEA=mRNA /GEN=FLJ12876 /PROD=hypothetical protein FLJ12876 /DB_XREF=gi:12232420 /UG=Hs.16131 hypothetical protein FLJ12876 /FL=gb:NM_022754.1 NM_022754 sideroflexin 1 SFXN1 94081 NM_022754 /// XM_005266012 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 218393_s_at NM_018225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018225.1 /DEF=Homo sapiens hypothetical protein FLJ10805 (FLJ10805), mRNA. /FEA=mRNA /GEN=FLJ10805 /PROD=hypothetical protein FLJ10805 /DB_XREF=gi:8922678 /UG=Hs.193128 hypothetical protein FLJ10805 /FL=gb:BC002876.1 gb:NM_018225.1 NM_018225 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) SMU1 55234 NM_018225 /// XM_005251503 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218394_at NM_024589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024589.1 /DEF=Homo sapiens hypothetical protein FLJ22386 (FLJ22386), mRNA. /FEA=mRNA /GEN=FLJ22386 /PROD=hypothetical protein FLJ22386 /DB_XREF=gi:13375778 /UG=Hs.22795 hypothetical protein FLJ22386 /FL=gb:AL136675.1 gb:NM_024589.1 NM_024589 rogdi homolog (Drosophila) ROGDI 79641 NM_024589 /// NR_046480 /// XM_006720947 /// XM_006720948 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation 218395_at NM_022496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022496.1 /DEF=Homo sapiens hypothetical protein FLJ13433 (FLJ13433), mRNA. /FEA=mRNA /GEN=FLJ13433 /PROD=hypothetical protein FLJ13433 /DB_XREF=gi:11968056 /UG=Hs.23259 hypothetical protein FLJ13433 /FL=gb:NM_022496.1 gb:AB038229.1 gb:AF212251.1 NM_022496 ARP6 actin-related protein 6 homolog (yeast) ACTR6 64431 NM_022496 /// NR_048568 /// NR_048569 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218396_at NM_017684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017684.1 /DEF=Homo sapiens hypothetical protein FLJ20136 (FLJ20136), mRNA. /FEA=mRNA /GEN=FLJ20136 /PROD=hypothetical protein FLJ20136 /DB_XREF=gi:8923138 /UG=Hs.24817 hypothetical protein FLJ20136 /FL=gb:NM_017684.1 NM_017684 vacuolar protein sorting 13 homolog C (S. cerevisiae) VPS13C 54832 NM_001018088 /// NM_017684 /// NM_018080 /// NM_020821 0070062 // extracellular vesicular exosome // inferred from direct assay 218397_at NM_018062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018062.1 /DEF=Homo sapiens hypothetical protein FLJ10335 (FLJ10335), mRNA. /FEA=mRNA /GEN=FLJ10335 /PROD=hypothetical protein FLJ10335 /DB_XREF=gi:8922359 /UG=Hs.279841 hypothetical protein FLJ10335 /FL=gb:NM_018062.1 NM_018062 Fanconi anemia, complementation group L FANCL 55120 NM_001114636 /// NM_018062 /// XM_005264395 /// XM_005264397 /// XM_006712038 /// XR_426986 0006281 // DNA repair // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007276 // gamete generation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218398_at NM_016640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016640.1 /DEF=Homo sapiens programmed cell death 9 (PDCD9), mRNA. /FEA=mRNA /GEN=PDCD9 /PROD=(HSA)PAP protein /DB_XREF=gi:7706187 /UG=Hs.28555 programmed cell death 9 /FL=gb:AL136706.1 gb:BC002460.1 gb:AF146192.2 gb:AF217523.1 gb:NM_016640.1 NM_016640 mitochondrial ribosomal protein S30 MRPS30 10884 NM_016640 0006412 // translation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218399_s_at NM_017955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017955.1 /DEF=Homo sapiens hypothetical protein FLJ20764 (FLJ20764), mRNA. /FEA=mRNA /GEN=FLJ20764 /PROD=hypothetical protein FLJ20764 /DB_XREF=gi:8923673 /UG=Hs.34045 hypothetical protein FLJ20764 /FL=gb:NM_017955.1 NM_017955 cell division cycle associated 4 CDCA4 55038 NM_017955 /// NM_145701 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218400_at NM_006187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006187.1 /DEF=Homo sapiens 2-5oligoadenylate synthetase 3 (OAS3), mRNA. /FEA=mRNA /GEN=OAS3 /PROD=2-5oligoadenylate synthetase 3 /DB_XREF=gi:5453823 /UG=Hs.56009 2-5oligoadenylate synthetase 3 /FL=gb:AB044545.1 gb:AF063613.1 gb:NM_006187.1 NM_006187 2'-5'-oligoadenylate synthetase 3, 100kDa OAS3 4940 NM_006187 /// XM_005253889 0002376 // immune system process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060700 // regulation of ribonuclease activity // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218401_s_at NM_012482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012482.1 /DEF=Homo sapiens zinc finger protein 281 (ZNF281), mRNA. /FEA=mRNA /GEN=ZNF281 /PROD=zinc finger protein 281 /DB_XREF=gi:6912751 /UG=Hs.59757 zinc finger protein 281 /FL=gb:AF125158.1 gb:NM_012482.1 NM_012482 zinc finger protein 281 ZNF281 23528 NM_001281293 /// NM_001281294 /// NM_012482 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218402_s_at NM_022081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022081.1 /DEF=Homo sapiens hypothetical protein bK1048E9.5 (BK1048E9.5), mRNA. /FEA=mRNA /GEN=BK1048E9.5 /PROD=hypothetical protein bK1048E9.5 /DB_XREF=gi:11559920 /UG=Hs.6657 hypothetical protein bK1048E9.5 /FL=gb:NM_022081.1 NM_022081 Hermansky-Pudlak syndrome 4 HPS4 89781 NM_022081 /// NM_152840 /// NM_152841 /// NM_152842 /// NM_152843 /// NR_073135 /// NR_073136 /// XM_006724353 /// XM_006724354 /// XM_006724355 /// XM_006724356 /// XM_006724357 /// XM_006724358 /// XM_006724359 /// XM_006724360 /// XM_006724361 /// XM_006724362 /// XM_006724363 0006605 // protein targeting // inferred from direct assay /// 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // traceable author statement /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0048075 // positive regulation of eye pigmentation // traceable author statement /// 0050821 // protein stabilization // inferred from physical interaction 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031085 // BLOC-3 complex // inferred from physical interaction /// 0042470 // melanosome // inferred from direct assay /// 0042827 // platelet dense granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 218403_at NM_016399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016399.1 /DEF=Homo sapiens hypothetical protein (HSPC132), mRNA. /FEA=mRNA /GEN=HSPC132 /PROD=hypothetical protein /DB_XREF=gi:7705466 /UG=Hs.69499 hypothetical protein /FL=gb:BC002638.1 gb:AF161481.1 gb:NM_016399.1 NM_016399 TP53 regulated inhibitor of apoptosis 1 TRIAP1 51499 NM_016399 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0015914 // phospholipid transport // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097035 // regulation of membrane lipid distribution // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 2001140 // positive regulation of phospholipid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 1990050 // phosphatidic acid transporter activity // inferred from direct assay 218404_at NM_013322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013322.1 /DEF=Homo sapiens sorting nexin 10 (SNX10), mRNA. /FEA=mRNA /GEN=SNX10 /PROD=sorting nexin 10 /DB_XREF=gi:7019536 /UG=Hs.106260 sorting nexin 10 /FL=gb:AF121860.1 gb:NM_013322.1 NM_013322 sorting nexin 10 SNX10 29887 NM_001199835 /// NM_001199837 /// NM_001199838 /// NM_013322 /// NR_037670 /// XM_006715710 /// XM_006715711 /// XM_006715712 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0061512 // protein localization to cilium // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031313 // extrinsic component of endosome membrane // inferred from direct assay 0005545 // 1-phosphatidylinositol binding // inferred from mutant phenotype /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 218405_at NM_013375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013375.1 /DEF=Homo sapiens TATA-binding protein-binding protein (ABT1), mRNA. /FEA=mRNA /GEN=ABT1 /PROD=TATA-binding protein-binding protein /DB_XREF=gi:7019318 /UG=Hs.109428 TATA-binding protein-binding protein /FL=gb:AB027258.1 gb:NM_013375.1 NM_013375 activator of basal transcription 1 ABT1 29777 NM_013375 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218406_x_at AF173937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF173937.1 /DEF=Homo sapiens secreted protein of unknown function (SPUF), mRNA, complete cds. /FEA=mRNA /GEN=SPUF /PROD=secreted protein of unknown function /DB_XREF=gi:5771534 /UG=Hs.109494 secreted protein of unknown function /FL=gb:AF173937.1 gb:NM_013349.1 AF173937 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218407_x_at NM_013349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013349.1 /DEF=Homo sapiens secreted protein of unknown function (SPUF), mRNA. /FEA=mRNA /GEN=SPUF /PROD=secreted protein of unknown function /DB_XREF=gi:7019544 /UG=Hs.109494 secreted protein of unknown function /FL=gb:AF173937.1 gb:NM_013349.1 NM_013349 neudesin neurotrophic factor NENF 29937 NM_013349 /// NR_026598 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218408_at NM_012456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012456.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 10 (yeast) homolog (TIMM10), mRNA. /FEA=mRNA /GEN=TIMM10 /PROD=translocase of inner mitochondrial membrane 10(yeast) homolog /DB_XREF=gi:6912707 /UG=Hs.109571 translocase of inner mitochondrial membrane 10 (yeast) homolog /FL=gb:AF150089.1 gb:AF152354.1 gb:NM_012456.1 NM_012456 translocase of inner mitochondrial membrane 10 homolog (yeast) TIMM10 26519 NM_012456 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045039 // protein import into mitochondrial inner membrane // inferred from direct assay /// 0045039 // protein import into mitochondrial inner membrane // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // traceable author statement /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042719 // mitochondrial intermembrane space protein transporter complex // inferred from direct assay 0005215 // transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 218409_s_at NM_022365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022365.1 /DEF=Homo sapiens hypothetical protein similar to mouse Dnajl1 (DNAJL1), mRNA. /FEA=mRNA /GEN=DNAJL1 /PROD=hypothetical protein similar to mouse Dnajl1 /DB_XREF=gi:11641286 /UG=Hs.13015 hypothetical protein similar to mouse Dnajl1 /FL=gb:NM_022365.1 NM_022365 DnaJ (Hsp40) homolog, subfamily C, member 1 DNAJC1 64215 NM_022365 0006417 // regulation of translation // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // traceable author statement /// 0045861 // negative regulation of proteolysis // traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001671 // ATPase activator activity // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation 218410_s_at NM_024118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024118.1 /DEF=Homo sapiens hypothetical protein MGC4692 (MGC4692), mRNA. /FEA=mRNA /GEN=MGC4692 /PROD=hypothetical protein MGC4692 /DB_XREF=gi:13129139 /UG=Hs.13561 hypothetical protein MGC4692 /FL=gb:BC002330.1 gb:NM_024118.1 NM_024118 phosphoglycolate phosphatase PGP 283871 NM_001042371 /// XR_243274 /// XR_243275 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from sequence or structural similarity /// 0008967 // phosphoglycolate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0098519 // nucleotide phosphatase activity, acting on free nucleotides // inferred from sequence or structural similarity 218411_s_at NM_016586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016586.1 /DEF=Homo sapiens MBIP protein (MBIP), mRNA. /FEA=mRNA /GEN=MBIP /PROD=MBIP protein /DB_XREF=gi:7706610 /UG=Hs.16755 MBIP protein /FL=gb:BC005197.1 gb:AB038523.1 gb:NM_016586.1 NM_016586 MAP3K12 binding inhibitory protein 1 MBIP 51562 NM_001144891 /// NM_016586 /// XM_005267754 /// XM_005267755 /// XM_005267756 0000173 // inactivation of MAPK activity involved in osmosensory signaling pathway // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218412_s_at NM_016328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016328.1 /DEF=Homo sapiens GTF2I repeat domain-containing 1 (GTF2IRD1), mRNA. /FEA=mRNA /GEN=GTF2IRD1 /PROD=general transcription factor 3 /DB_XREF=gi:7705386 /UG=Hs.21075 GTF2I repeat domain-containing 1 /FL=gb:AF151354.1 gb:AF089107.1 gb:NM_016328.1 NM_016328 GTF2I repeat domain containing 1 GTF2IRD1 9569 NM_001199207 /// NM_005685 /// NM_016328 /// XM_005250720 /// XM_005250721 /// XM_006716182 /// XM_006716183 /// XM_006716184 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // non-traceable author statement 218413_s_at NM_016331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016331.1 /DEF=Homo sapiens zinc finger protein ANC_2H01 (LOC51193), mRNA. /FEA=mRNA /GEN=LOC51193 /PROD=zinc finger protein ANC_2H01 /DB_XREF=gi:7705934 /UG=Hs.22879 zinc finger protein ANC_2H01 /FL=gb:AF003924.1 gb:NM_016331.1 NM_016331 zinc finger protein 639 ZNF639 51193 NM_016331 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043922 // negative regulation by host of viral transcription // inferred from mutant phenotype /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046718 // viral entry into host cell // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218414_s_at NM_017668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017668.1 /DEF=Homo sapiens LIS1-interacting protein NUDE1, rat homolog (FLJ20101), mRNA. /FEA=mRNA /GEN=FLJ20101 /PROD=LIS1-interacting protein NUDE1, rat homolog /DB_XREF=gi:8923109 /UG=Hs.263925 LIS1-interacting protein NUDE1, rat homolog /FL=gb:BC001421.1 gb:NM_017668.1 NM_017668 nudE neurodevelopment protein 1 NDE1 54820 NM_001143979 /// NM_017668 /// XM_005255396 /// XM_006720897 /// XM_006720898 /// XM_006720899 /// XM_006720900 /// XM_006725200 /// XM_006725201 /// XM_006725202 /// XM_006725203 /// XM_006725204 /// XR_243289 /// XR_430724 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0007020 // microtubule nucleation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from sequence or structural similarity /// 0032154 // cleavage furrow // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 218415_at NM_018668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018668.1 /DEF=Homo sapiens vacuolar protein sorting 33B (yeast homolog) (VPS33B), mRNA. /FEA=mRNA /GEN=VPS33B /PROD=vacuolar protein sorting 33B (yeast homolog) /DB_XREF=gi:9945311 /UG=Hs.26510 vacuolar protein sorting 33B (yeast homolog) /FL=gb:AF308803.1 gb:AF201694.1 gb:NM_018668.1 NM_018668 vacuolar protein sorting 33 homolog B (yeast) VPS33B 26276 NM_001289148 /// NM_001289149 /// NM_018668 /// XM_005254884 /// XM_005254887 /// XM_005254888 /// XM_006720471 0006810 // transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0032400 // melanosome localization // inferred from direct assay /// 0032418 // lysosome localization // inferred from direct assay /// 0061025 // membrane fusion // inferred from mutant phenotype /// 0070889 // platelet alpha granule organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218416_s_at AW149696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149696 /FEA=EST /DB_XREF=gi:6197592 /DB_XREF=est:xf41c04.x1 /CLONE=IMAGE:2620614 /UG=Hs.267368 hypothetical protein FLJ20489 /FL=gb:NM_017842.1 AW149696 solute carrier family 48 (heme transporter), member 1 SLC48A1 55652 NM_017842 /// XM_005269016 0006810 // transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015232 // heme transporter activity // inferred from electronic annotation 218417_s_at NM_017842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017842.1 /DEF=Homo sapiens hypothetical protein FLJ20489 (FLJ20489), mRNA. /FEA=mRNA /GEN=FLJ20489 /PROD=hypothetical protein FLJ20489 /DB_XREF=gi:8923451 /UG=Hs.267368 hypothetical protein FLJ20489 /FL=gb:NM_017842.1 NM_017842 solute carrier family 48 (heme transporter), member 1 SLC48A1 55652 NM_017842 /// XM_005269016 0006810 // transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015232 // heme transporter activity // inferred from electronic annotation 218418_s_at NM_015493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015493.1 /DEF=Homo sapiens DKFZP434N161 protein (DKFZP434N161), mRNA. /FEA=mRNA /GEN=DKFZP434N161 /PROD=DKFZP434N161 protein /DB_XREF=gi:7661583 /UG=Hs.284208 DKFZP434N161 protein /FL=gb:NM_015493.1 NM_015493 KN motif and ankyrin repeat domains 2 KANK2 25959 NM_001136191 /// NM_015493 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218419_s_at NM_024107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024107.1 /DEF=Homo sapiens hypothetical protein MGC3123 (MGC3123), mRNA. /FEA=mRNA /GEN=MGC3123 /PROD=hypothetical protein MGC3123 /DB_XREF=gi:13129117 /UG=Hs.288600 hypothetical protein MGC3123 /FL=gb:BC001792.1 gb:NM_024107.1 NM_024107 transmembrane and ubiquitin-like domain containing 2 TMUB2 79089 NM_001076674 /// NM_024107 /// NM_177441 /// XM_005257650 /// XM_006722076 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218420_s_at NM_025138 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025138.1 /DEF=Homo sapiens hypothetical protein FLJ12661 (FLJ12661), mRNA. /FEA=mRNA /GEN=FLJ12661 /PROD=hypothetical protein FLJ12661 /DB_XREF=gi:13376720 /UG=Hs.318526 hypothetical protein FLJ12661 /FL=gb:NM_025138.1 NM_025138 proline and serine rich 1 PROSER1 80209 NM_025138 /// NM_170719 /// XM_005266545 218421_at NM_022766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022766.1 /DEF=Homo sapiens hypothetical protein FLJ23239 (FLJ23239), mRNA. /FEA=mRNA /GEN=FLJ23239 /PROD=hypothetical protein FLJ23239 /DB_XREF=gi:12232440 /UG=Hs.34516 hypothetical protein FLJ23239 /FL=gb:NM_022766.1 gb:BC004278.1 NM_022766 ceramide kinase CERK 64781 NM_022766 /// NM_182661 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // inferred from direct assay /// 0006672 // ceramide metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046834 // lipid phosphorylation // inferred from direct assay /// 0046834 // lipid phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0001729 // ceramide kinase activity // inferred from direct assay /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218422_s_at NM_022118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022118.1 /DEF=Homo sapiens cutaneous T-cell lymphoma tumor antigen se70-2 (SE70-2), mRNA. /FEA=mRNA /GEN=SE70-2 /PROD=cutaneous T-cell lymphoma tumor antigen se70-2 /DB_XREF=gi:11545836 /UG=Hs.39140 cutaneous T-cell lymphoma tumor antigen se70-2 /FL=gb:AF273052.1 gb:NM_022118.1 gb:BC000791.1 NM_022118 RNA binding motif protein 26 RBM26 64062 NM_001286631 /// NM_001286632 /// NM_018605 /// NM_022118 /// XM_005266491 /// XM_005266492 /// XM_005266493 /// XM_005266494 /// XM_005266496 /// XM_005266497 /// XM_005266498 /// XM_005266499 /// XM_005266501 /// XM_006719855 /// XM_006719856 /// XM_006719857 /// XM_006719858 /// XM_006719859 /// XM_006719860 0006397 // mRNA processing // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218423_x_at NM_016516 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016516.1 /DEF=Homo sapiens tumor antigen SLP-8p (HCC8), mRNA. /FEA=mRNA /GEN=HCC8 /PROD=tumor antigen SLP-8p /DB_XREF=gi:7705396 /UG=Hs.48499 tumor antigen SLP-8p /FL=gb:AF102177.1 gb:NM_016516.1 NM_016516 vacuolar protein sorting 54 homolog (S. cerevisiae) VPS54 51542 NM_001005739 /// NM_016516 /// XM_006712029 /// XR_244939 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050881 // musculoskeletal movement // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0000938 // GARP complex // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218424_s_at NM_018234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018234.1 /DEF=Homo sapiens hypothetical protein FLJ10829 (FLJ10829), mRNA. /FEA=mRNA /GEN=FLJ10829 /PROD=hypothetical protein FLJ10829 /DB_XREF=gi:8922696 /UG=Hs.57655 hypothetical protein FLJ10829 /FL=gb:NM_018234.1 NM_018234 STEAP family member 3, metalloreductase STEAP3 55240 NM_001008410 /// NM_018234 /// NM_182915 /// XM_006712613 /// XM_006712614 /// XM_006712615 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009306 // protein secretion // inferred from direct assay /// 0009306 // protein secretion // inferred from mutant phenotype /// 0033572 // transferrin transport // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000293 // ferric-chelate reductase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218425_at BC000787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000787.1 /DEF=Homo sapiens, TRIAD3 protein, clone MGC:998, mRNA, complete cds. /FEA=mRNA /PROD=TRIAD3 protein /DB_XREF=gi:12653980 /UG=Hs.86228 TRIAD3 protein /FL=gb:BC000787.1 gb:NM_019011.1 BC000787 ring finger protein 216 RNF216 54476 NM_019011 /// NM_207111 /// NM_207116 /// XM_005249785 /// XM_006715748 /// XR_242090 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032648 // regulation of interferon-beta production // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218426_s_at NM_019011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019011.1 /DEF=Homo sapiens TRIAD3 protein (TRIAD3), mRNA. /FEA=mRNA /GEN=TRIAD3 /PROD=TRIAD3 protein /DB_XREF=gi:9507204 /UG=Hs.86228 TRIAD3 protein /FL=gb:BC000787.1 gb:NM_019011.1 NM_019011 ring finger protein 216 RNF216 54476 NM_019011 /// NM_207111 /// NM_207116 /// XM_005249785 /// XM_006715748 /// XR_242090 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032648 // regulation of interferon-beta production // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218427_at NM_006643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006643.1 /DEF=Homo sapiens serologically defined colon cancer antigen 3 (SDCCAG3), mRNA. /FEA=mRNA /GEN=SDCCAG3 /PROD=serologically defined colon cancer antigen 3 /DB_XREF=gi:10281331 /UG=Hs.94300 serologically defined colon cancer antigen 3 /FL=gb:NM_006643.1 NM_006643 serologically defined colon cancer antigen 3 SDCCAG3 10807 NM_001039707 /// NM_001039708 /// NM_006643 /// XM_005266050 /// XM_005266051 0005737 // cytoplasm // inferred from electronic annotation 218428_s_at NM_016316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016316.1 /DEF=Homo sapiens REV1 (yeast homolog)- like (REV1L), mRNA. /FEA=mRNA /GEN=REV1L /PROD=REV1 (yeast homolog)- like /DB_XREF=gi:7706680 /UG=Hs.110347 REV1 (yeast homolog)- like /FL=gb:AB047646.1 gb:AF151538.1 gb:AF206019.1 gb:NM_016316.1 NM_016316 REV1, polymerase (DNA directed) REV1 51455 NM_001037872 /// NM_016316 /// XM_005263968 /// XM_006712592 /// XM_006712593 /// XR_244891 /// XR_427091 /// XR_427092 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0042276 // error-prone translesion synthesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0017125 // deoxycytidyl transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218429_s_at NM_018381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018381.1 /DEF=Homo sapiens hypothetical protein FLJ11286 (FLJ11286), mRNA. /FEA=mRNA /GEN=FLJ11286 /PROD=hypothetical protein FLJ11286 /DB_XREF=gi:8922978 /UG=Hs.12151 hypothetical protein FLJ11286 /FL=gb:NM_018381.1 NM_018381 chromosome 19 open reading frame 66 C19orf66 55337 NM_018381 /// XM_006722786 /// XM_006722787 /// XM_006722788 218430_s_at NM_022841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022841.1 /DEF=Homo sapiens hypothetical protein FLJ12994 (FLJ12994), mRNA. /FEA=mRNA /GEN=FLJ12994 /PROD=hypothetical protein FLJ12994 /DB_XREF=gi:12383091 /UG=Hs.126908 hypothetical protein FLJ12994 /FL=gb:NM_022841.1 NM_022841 regulatory factor X, 7 RFX7 64864 NM_022841 /// XM_005254603 /// XM_006720646 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 218431_at NM_022067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022067.1 /DEF=Homo sapiens hypothetical protein FLJ12707 (FLJ12707), mRNA. /FEA=mRNA /GEN=FLJ12707 /PROD=hypothetical protein FLJ12707 /DB_XREF=gi:11545778 /UG=Hs.16157 hypothetical protein FLJ12707 /FL=gb:NM_022067.1 NM_022067 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog VIPAS39 63894 NM_001193314 /// NM_001193315 /// NM_001193316 /// NM_001193317 /// NM_022067 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218432_at NM_012175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012175.1 /DEF=Homo sapiens F-box only protein 3 (FBXO3), mRNA. /FEA=mRNA /GEN=FBXO3 /PROD=F-box only protein 3 /DB_XREF=gi:10281333 /UG=Hs.16577 F-box only protein 3 /FL=gb:NM_012175.1 NM_012175 F-box protein 3 FBXO3 26273 NM_012175 /// NM_033406 /// XM_005252851 0006508 // proteolysis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218433_at NM_024594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024594.1 /DEF=Homo sapiens hypothetical protein FLJ12899 (FLJ12899), mRNA. /FEA=mRNA /GEN=FLJ12899 /PROD=hypothetical protein FLJ12899 /DB_XREF=gi:13375788 /UG=Hs.23744 hypothetical protein FLJ12899 /FL=gb:NM_024594.1 NM_024594 pantothenate kinase 3 PANK3 79646 NM_024594 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004594 // pantothenate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218434_s_at NM_023928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023928.1 /DEF=Homo sapiens hypothetical protein FLJ12389 similar to acetoacetyl-CoA synthetase (FLJ12389), mRNA. /FEA=mRNA /GEN=FLJ12389 /PROD=hypothetical protein FLJ12389 similar toacetoacetyl-CoA synthetase /DB_XREF=gi:12965198 /UG=Hs.239758 hypothetical protein FLJ12389 similar to acetoacetyl-CoA synthetase /FL=gb:NM_023928.1 NM_023928 acetoacetyl-CoA synthetase AACS 65985 NM_023928 /// XM_005253609 /// XM_005253610 /// XM_005253611 /// XR_242960 0001889 // liver development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014074 // response to purine-containing compound // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071394 // cellular response to testosterone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030729 // acetoacetate-CoA ligase activity // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 218435_at NM_013238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013238.1 /DEF=Homo sapiens DNAJ domain-containing (MCJ), mRNA. /FEA=mRNA /GEN=MCJ /PROD=DNAJ domain-containing /DB_XREF=gi:7019452 /UG=Hs.279884 DNAJ domain-containing /FL=gb:AF126743.1 gb:NM_013238.1 NM_013238 DnaJ (Hsp40) homolog, subfamily C, member 15 DNAJC15 29103 NM_013238 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218436_at NM_022464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022464.1 /DEF=Homo sapiens endoplasmic reticulum chaperone SIL1, homolog of yeast (SIL1), mRNA. /FEA=mRNA /GEN=SIL1 /PROD=endoplasmic reticulum chaperone SIL1, homolog ofyeast /DB_XREF=gi:11968008 /UG=Hs.297875 endoplasmic reticulum chaperone SIL1, homolog of yeast /FL=gb:NM_022464.1 NM_022464 SIL1 nucleotide exchange factor SIL1 64374 NM_001037633 /// NM_022464 /// XM_006714671 0006457 // protein folding // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 218437_s_at NM_020347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020347.1 /DEF=Homo sapiens leucine zipper transcription factor-like 1 (LZTFL1), mRNA. /FEA=mRNA /GEN=LZTFL1 /PROD=leucine zipper transcription factor-like 1 /DB_XREF=gi:9966792 /UG=Hs.30824 leucine zipper transcription factor-like 1 /FL=gb:NM_020347.1 NM_020347 leucine zipper transcription factor-like 1 LZTFL1 54585 NM_001276378 /// NM_001276379 /// NM_020347 /// NR_075080 /// XM_006713207 0072594 // establishment of protein localization to organelle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218438_s_at NM_025205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025205.1 /DEF=Homo sapiens hypothetical protein DKFZp434N185 (DKFZP434N185), mRNA. /FEA=mRNA /GEN=DKFZP434N185 /PROD=hypothetical protein DKFZp434N185 /DB_XREF=gi:13376801 /UG=Hs.33032 hypothetical protein DKFZp434N185 /FL=gb:AF317680.1 gb:NM_025205.1 NM_025205 mediator complex subunit 28 MED28 80306 NM_025205 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0051151 // negative regulation of smooth muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218439_s_at NM_016144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016144.1 /DEF=Homo sapiens PTD002 protein (PTD002), mRNA. /FEA=mRNA /GEN=PTD002 /PROD=PTD002 protein /DB_XREF=gi:7706662 /UG=Hs.41767 PTD002 protein /FL=gb:BC005179.1 gb:AF078857.1 gb:NM_016144.1 NM_016144 COMM domain containing 10 COMMD10 51397 NM_016144 0005515 // protein binding // inferred from physical interaction 218440_at NM_020166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020166.2 /DEF=Homo sapiens methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) (MCCC1), mRNA. /FEA=mRNA /GEN=MCCC1 /PROD=methylcrotonoyl-Coenzyme A carboxylase 1(alpha) /DB_XREF=gi:13518227 /UG=Hs.47649 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) /FL=gb:AF310339.1 gb:AF310972.1 gb:BC004187.1 gb:BC004214.1 gb:NM_020166.2 gb:AB029826.1 NM_020166 methylcrotonoyl-CoA carboxylase 1 (alpha) MCCC1 56922 NM_001293273 /// NM_020166 /// NR_120639 /// NR_120640 /// XM_006713702 /// XR_241502 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // non-traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0004485 // methylcrotonoyl-CoA carboxylase activity // inferred from direct assay /// 0004485 // methylcrotonoyl-CoA carboxylase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0009374 // biotin binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218441_s_at NM_015540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015540.1 /DEF=Homo sapiens DKFZP727M111 protein (DKFZP727M111), mRNA. /FEA=mRNA /GEN=DKFZP727M111 /PROD=DKFZP727M111 protein /DB_XREF=gi:13027585 /UG=Hs.4849 DKFZP727M111 protein /FL=gb:BC000246.1 gb:NM_015540.1 NM_015540 RNA polymerase II associated protein 1 RPAP1 26015 NM_015540 /// XM_005254297 /// XM_006720469 /// XM_006720470 0008152 // metabolic process // inferred from electronic annotation /// 0032774 // RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 218442_at NM_004623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004623.1 /DEF=Homo sapiens tetratricopeptide repeat domain 4 (TTC4), mRNA. /FEA=mRNA /GEN=TTC4 /PROD=tetratricopeptide repeat domain 4 /DB_XREF=gi:4759271 /UG=Hs.5990 tetratricopeptide repeat domain 4 /FL=gb:AF063602.1 gb:BC001276.1 gb:AF073887.1 gb:NM_004623.1 NM_004623 tetratricopeptide repeat domain 4 TTC4 7268 NM_001291333 /// NM_004623 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218443_s_at NM_018959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018959.1 /DEF=Homo sapiens DAZ associated protein 1 (DAZAP1), mRNA. /FEA=mRNA /GEN=DAZAP1 /PROD=DAZ associated protein 1 /DB_XREF=gi:9506536 /UG=Hs.65588 DAZ associated protein 1 /FL=gb:AF181719.1 gb:NM_018959.1 NM_018959 DAZ associated protein 1 DAZAP1 26528 NM_018959 /// NM_170711 /// XM_005259530 /// XM_005259531 /// XM_005259532 /// XM_005259534 /// XM_005259535 /// XM_005259536 0001893 // maternal placenta development // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0035613 // RNA stem-loop binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218444_at NM_024105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024105.1 /DEF=Homo sapiens hypothetical protein MGC3136 (MGC3136), mRNA. /FEA=mRNA /GEN=MGC3136 /PROD=hypothetical protein MGC3136 /DB_XREF=gi:13129113 /UG=Hs.77575 hypothetical protein MGC3136 /FL=gb:BC001729.1 gb:NM_024105.1 NM_024105 ALG12, alpha-1,6-mannosyltransferase ALG12 79087 NM_024105 0006457 // protein folding // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from genetic interaction /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // inferred from direct assay /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred by curator /// 0097502 // mannosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000009 // alpha-1,6-mannosyltransferase activity // inferred by curator /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052917 // dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity // inferred from electronic annotation 218445_at NM_018649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018649.1 /DEF=Homo sapiens core histone macroH2A2.2 (MACROH2A2), mRNA. /FEA=mRNA /GEN=MACROH2A2 /PROD=core histone macroH2A2.2 /DB_XREF=gi:8923919 /UG=Hs.92023 core histone macroH2A2.2 /FL=gb:AF151534.1 gb:NM_018649.1 NM_018649 H2A histone family, member Y2 H2AFY2 55506 NM_018649 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001558 // regulation of cell growth // inferred from genetic interaction /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007549 // dosage compensation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045814 // negative regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from genetic interaction 0000786 // nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218446_s_at NM_016078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016078.1 /DEF=Homo sapiens CGI-148 protein (LOC51030), mRNA. /FEA=mRNA /GEN=LOC51030 /PROD=CGI-148 protein /DB_XREF=gi:7705643 /UG=Hs.6776 CGI-148 protein /FL=gb:AF151906.1 gb:AF223467.1 gb:NM_016078.1 NM_016078 trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) TVP23B 51030 NM_016078 /// XM_005256673 /// XM_005256674 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218447_at NM_020188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020188.1 /DEF=Homo sapiens DC13 protein (DC13), mRNA. /FEA=mRNA /GEN=DC13 /PROD=DC13 protein /DB_XREF=gi:9910183 /UG=Hs.6879 DC13 protein /FL=gb:AF201935.1 gb:NM_020188.1 NM_020188 C-x(9)-C motif containing 2 CMC2 56942 NM_020188 /// XM_005256056 /// XM_005256057 /// XM_005256058 0005739 // mitochondrion // inferred from direct assay 218448_at NM_017896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017896.1 /DEF=Homo sapiens hypothetical protein FLJ20602 (FLJ20602), mRNA. /FEA=mRNA /GEN=FLJ20602 /PROD=hypothetical protein FLJ20602 /DB_XREF=gi:8923556 /UG=Hs.103808 hypothetical protein FLJ20602 /FL=gb:NM_017896.1 NM_017896 GID complex subunit 8 GID8 54994 NM_017896 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218449_at NM_018359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018359.1 /DEF=Homo sapiens hypothetical protein FLJ11200 (FLJ11200), mRNA. /FEA=mRNA /GEN=FLJ11200 /PROD=hypothetical protein FLJ11200 /DB_XREF=gi:8922937 /UG=Hs.107381 hypothetical protein FLJ11200 /FL=gb:NM_018359.1 NM_018359 UFM1-specific peptidase 2 UFSP2 55325 NM_018359 /// NR_028085 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // inferred from electronic annotation /// 0019783 // small conjugating protein-specific protease activity // inferred from sequence or structural similarity 218450_at NM_015987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015987.1 /DEF=Homo sapiens heme-binding protein (HEBP), mRNA. /FEA=mRNA /GEN=HEBP /PROD=heme-binding protein /DB_XREF=gi:7705404 /UG=Hs.108675 heme-binding protein /FL=gb:AF117615.1 gb:NM_015987.1 gb:AF167473.1 NM_015987 heme binding protein 1 HEBP1 50865 NM_015987 0007623 // circadian rhythm // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0020037 // heme binding // inferred from sequence or structural similarity 218451_at NM_022842 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022842.1 /DEF=Homo sapiens hypothetical protein FLJ22969 (FLJ22969), mRNA. /FEA=mRNA /GEN=FLJ22969 /PROD=hypothetical protein FLJ22969 /DB_XREF=gi:12383093 /UG=Hs.146170 hypothetical protein FLJ22969 /FL=gb:NM_022842.1 NM_022842 CUB domain containing protein 1 CDCP1 64866 NM_022842 /// NM_178181 /// XM_005265404 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218452_at NM_014140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014140.1 /DEF=Homo sapiens HepA-related protein (HARP), mRNA. /FEA=mRNA /GEN=HARP /PROD=HepA-related protein /DB_XREF=gi:7657149 /UG=Hs.16933 HepA-related protein /FL=gb:AF082179.1 gb:NM_014140.1 NM_014140 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 SMARCAL1 50485 NM_001127207 /// NM_014140 /// XM_005246631 /// XM_005246632 /// XM_006712557 0000733 // DNA strand renaturation // inferred from direct assay /// 0000733 // DNA strand renaturation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006259 // DNA metabolic process // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0036310 // annealing helicase activity // inferred from mutant phenotype 218453_s_at NM_018452 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018452.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM033 (BM033), mRNA. /FEA=mRNA /GEN=BM033 /PROD=uncharacterized bone marrow protein BM033 /DB_XREF=gi:8922090 /UG=Hs.173259 uncharacterized bone marrow protein BM033 /FL=gb:AF217510.1 gb:NM_018452.1 NM_018452 transmembrane protein 242 TMEM242 729515 NM_018452 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218454_at NM_024829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024829.1 /DEF=Homo sapiens hypothetical protein FLJ22662 (FLJ22662), mRNA. /FEA=mRNA /GEN=FLJ22662 /PROD=hypothetical protein FLJ22662 /DB_XREF=gi:13376231 /UG=Hs.178470 hypothetical protein FLJ22662 /FL=gb:NM_024829.1 NM_024829 phospholipase B domain containing 1 PLBD1 79887 NM_024829 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0016787 // hydrolase activity // inferred from electronic annotation 218455_at NM_021100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021100.1 /DEF=Homo sapiens cysteine desulfurase (NIFS), mRNA. /FEA=mRNA /GEN=NIFS /PROD=cysteine desulfurase /DB_XREF=gi:10864078 /UG=Hs.194692 cysteine desulfurase /FL=gb:NM_021100.1 gb:AF097025.1 NM_021100 NFS1 cysteine desulfurase NFS1 9054 NM_001198989 /// NM_021100 /// NM_181679 /// NR_037570 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006534 // cysteine metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018283 // iron incorporation into metallo-sulfur cluster // inferred from direct assay /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0031071 // cysteine desulfurase activity // not recorded /// 0031071 // cysteine desulfurase activity // inferred from direct assay /// 0031071 // cysteine desulfurase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 218456_at NM_023925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023925.1 /DEF=Homo sapiens hypothetical protein FLJ22569 (FLJ22569), mRNA. /FEA=mRNA /GEN=FLJ22569 /PROD=hypothetical protein FLJ22569 /DB_XREF=gi:12965192 /UG=Hs.234355 hypothetical protein FLJ22569 /FL=gb:NM_023925.1 NM_023925 caprin family member 2 CAPRIN2 65981 NM_001002259 /// NM_001206856 /// NM_023925 /// NM_032156 /// NR_038177 /// XM_006719137 /// XM_006719138 /// XM_006719139 /// XM_006719140 /// XM_006719141 /// XM_006719142 /// XM_006719143 /// XM_006719144 /// XM_006719145 /// XM_006719146 /// XM_006719147 /// XM_006719148 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 218457_s_at NM_022552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022552.2 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), mRNA. /FEA=mRNA /GEN=DNMT3A /PROD=DNA (cytosine-5-)-methyltransferase 3 alpha /DB_XREF=gi:12751472 /UG=Hs.241565 DNA (cytosine-5-)-methyltransferase 3 alpha /FL=gb:AF067972.2 gb:NM_022552.2 NM_022552 DNA (cytosine-5-)-methyltransferase 3 alpha DNMT3A 1788 NM_022552 /// NM_153759 /// NM_175629 /// NM_175630 /// XM_005264175 /// XM_005264176 /// XM_005264177 /// XM_006711957 /// XM_006711958 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from direct assay /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0043045 // DNA methylation involved in embryo development // inferred from electronic annotation /// 0043046 // DNA methylation involved in gamete generation // inferred from electronic annotation /// 0044027 // hypermethylation of CpG island // inferred from electronic annotation /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046499 // S-adenosylmethioninamine metabolic process // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0090116 // C-5 methylation of cytosine // inferred from direct assay /// 0090116 // C-5 methylation of cytosine // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000791 // euchromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0045322 // unmethylated CpG binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051718 // DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates // inferred from electronic annotation 218458_at NM_022471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022471.1 /DEF=Homo sapiens hypothetical protein FLJ13057 similar to germ cell-less (FLJ13057), mRNA. /FEA=mRNA /GEN=FLJ13057 /PROD=hypothetical protein FLJ13057 similar to germcell-less /DB_XREF=gi:11968020 /UG=Hs.243122 hypothetical protein FLJ13057 similar to germ cell-less /FL=gb:NM_022471.1 NM_022471 germ cell-less, spermatogenesis associated 1 GMCL1 64395 NM_178439 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218459_at NM_022371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022371.1 /DEF=Homo sapiens ATP-dependant interferon response protein 1 (ADIR), mRNA. /FEA=mRNA /GEN=ADIR /PROD=ATP-dependant interferon response protein 1 /DB_XREF=gi:11641298 /UG=Hs.26267 ATP-dependant interferon response protein 1 /FL=gb:NM_022371.1 gb:BC001085.1 NM_022371 torsin family 3, member A TOR3A 64222 NM_022371 /// XM_006711485 0006200 // ATP catabolic process // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay 218460_at NM_017802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017802.1 /DEF=Homo sapiens hypothetical protein FLJ20397 (FLJ20397), mRNA. /FEA=mRNA /GEN=FLJ20397 /PROD=hypothetical protein FLJ20397 /DB_XREF=gi:8923371 /UG=Hs.272688 hypothetical protein FLJ20397 /FL=gb:NM_017802.1 NM_017802 HEAT repeat containing 2 HEATR2 54919 NM_017802 /// NR_075098 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218461_at NM_016301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016301.1 /DEF=Homo sapiens protein x 0004 (LOC51184), mRNA. /FEA=mRNA /GEN=LOC51184 /PROD=protein x 0004 /DB_XREF=gi:9994188 /UG=Hs.284164 protein x 0004 /FL=gb:AF117229.1 gb:NM_016301.1 NM_016301 GPN-loop GTPase 3 GPN3 51184 NM_001164372 /// NM_001164373 /// NM_016301 /// XM_005253896 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218462_at NM_025065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025065.1 /DEF=Homo sapiens hypothetical protein FLJ12475 (FLJ12475), mRNA. /FEA=mRNA /GEN=FLJ12475 /PROD=hypothetical protein FLJ12475 /DB_XREF=gi:13376604 /UG=Hs.287863 hypothetical protein FLJ12475 /FL=gb:NM_025065.1 NM_025065 ribosome production factor 1 homolog (S. cerevisiae) RPF1 80135 NM_025065 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218463_s_at NM_025128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025128.1 /DEF=Homo sapiens hypothetical protein FLJ21012 (FLJ21012), mRNA. /FEA=mRNA /GEN=FLJ21012 /PROD=hypothetical protein FLJ21012 /DB_XREF=gi:13376706 /UG=Hs.288798 hypothetical protein FLJ21012 /FL=gb:NM_025128.1 NM_025128 MUS81 structure-specific endonuclease subunit MUS81 80198 NM_025128 /// XM_005274307 /// XR_247212 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0072429 // response to intra-S DNA damage checkpoint signaling // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048257 // 3'-flap endonuclease activity // inferred from mutant phenotype 218464_s_at NM_018182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018182.1 /DEF=Homo sapiens hypothetical protein FLJ10700 (FLJ10700), mRNA. /FEA=mRNA /GEN=FLJ10700 /PROD=hypothetical protein FLJ10700 /DB_XREF=gi:8922595 /UG=Hs.295909 hypothetical protein FLJ10700 /FL=gb:NM_018182.1 NM_018182 family with sequence similarity 222, member B FAM222B 55731 NM_001077498 /// NM_001288631 /// NM_001288632 /// NM_001288633 /// NM_001288634 /// NM_001288635 /// NM_001288636 /// NM_001288637 /// NM_001288638 /// NM_001288639 /// NM_001288640 /// NM_018182 /// XM_006721971 218465_at NM_018126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018126.1 /DEF=Homo sapiens hypothetical protein FLJ10525 (FLJ10525), mRNA. /FEA=mRNA /GEN=FLJ10525 /PROD=hypothetical protein FLJ10525 /DB_XREF=gi:8922490 /UG=Hs.31082 hypothetical protein FLJ10525 /FL=gb:BC000948.1 gb:NM_018126.1 NM_018126 transmembrane protein 33 TMEM33 55161 NM_018126 /// XM_005248116 /// XM_005248117 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218466_at NM_024682 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024682.1 /DEF=Homo sapiens hypothetical protein FLJ12168 (FLJ12168), mRNA. /FEA=mRNA /GEN=FLJ12168 /PROD=hypothetical protein FLJ12168 /DB_XREF=gi:13375951 /UG=Hs.325860 hypothetical protein FLJ12168 /FL=gb:BC003516.1 gb:NM_024682.1 NM_024682 TBC1 domain family, member 17 TBC1D17 79735 NM_001168222 /// NM_024682 /// XM_006723385 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 218467_at NM_020232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020232.1 /DEF=Homo sapiens x 003 protein (MDS003), mRNA. /FEA=mRNA /GEN=MDS003 /PROD=x 003 protein /DB_XREF=gi:9910421 /UG=Hs.3726 x 003 protein /FL=gb:AF168712.1 gb:NM_020232.1 NM_020232 proteasome (prosome, macropain) assembly chaperone 2 PSMG2 56984 NM_020232 /// NM_147163 0006915 // apoptotic process // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043248 // proteasome assembly // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 218468_s_at AF154054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF154054.1 /DEF=Homo sapiens DRM (DRM) mRNA, complete cds. /FEA=mRNA /GEN=DRM /PROD=DRM /DB_XREF=gi:10863087 /UG=Hs.40098 cysteine knot superfamily 1, BMP antagonist 1 /FL=gb:AF154054.1 gb:AF045800.1 gb:AF110137.2 gb:NM_013372.1 AF154054 gremlin 1, DAN family BMP antagonist GREM1 26585 NM_001191322 /// NM_001191323 /// NM_013372 /// XM_005254301 /// XM_006725542 0000902 // cell morphogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0002689 // negative regulation of leukocyte chemotaxis // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048263 // determination of dorsal identity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051893 // regulation of focal adhesion assembly // inferred from electronic annotation /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060676 // ureteric bud formation // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0072331 // signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090291 // negative regulation of osteoclast proliferation // inferred from mutant phenotype /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 1900155 // negative regulation of bone trabecula formation // inferred from mutant phenotype /// 1900158 // negative regulation of bone mineralization involved in bone maturation // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from sequence or structural similarity /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016015 // morphogen activity // inferred from sequence or structural similarity /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred from sequence or structural similarity /// 0036122 // BMP binding // inferred from sequence or structural similarity /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from sequence or structural similarity /// 0048018 // receptor agonist activity // inferred from sequence or structural similarity 218469_at NM_013372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013372.1 /DEF=Homo sapiens cysteine knot superfamily 1, BMP antagonist 1 (CKTSF1B1), mRNA. /FEA=mRNA /GEN=CKTSF1B1 /PROD=cysteine knot superfamily 1, BMP antagonist 1 /DB_XREF=gi:7019348 /UG=Hs.40098 cysteine knot superfamily 1, BMP antagonist 1 /FL=gb:AF154054.1 gb:AF045800.1 gb:AF110137.2 gb:NM_013372.1 NM_013372 gremlin 1, DAN family BMP antagonist GREM1 26585 NM_001191322 /// NM_001191323 /// NM_013372 /// XM_005254301 /// XM_006725542 0000902 // cell morphogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0002689 // negative regulation of leukocyte chemotaxis // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048263 // determination of dorsal identity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051893 // regulation of focal adhesion assembly // inferred from electronic annotation /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060676 // ureteric bud formation // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0072331 // signal transduction by p53 class mediator // inferred from sequence or structural similarity /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090291 // negative regulation of osteoclast proliferation // inferred from mutant phenotype /// 1900086 // positive regulation of peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 1900155 // negative regulation of bone trabecula formation // inferred from mutant phenotype /// 1900158 // negative regulation of bone mineralization involved in bone maturation // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from sequence or structural similarity /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016015 // morphogen activity // inferred from sequence or structural similarity /// 0030296 // protein tyrosine kinase activator activity // inferred from electronic annotation /// 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred from sequence or structural similarity /// 0036122 // BMP binding // inferred from sequence or structural similarity /// 0043184 // vascular endothelial growth factor receptor 2 binding // inferred from sequence or structural similarity /// 0048018 // receptor agonist activity // inferred from sequence or structural similarity 218470_at NM_015936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015936.1 /DEF=Homo sapiens CGI-04 protein (LOC51067), mRNA. /FEA=mRNA /GEN=LOC51067 /PROD=CGI-04 protein /DB_XREF=gi:7705709 /UG=Hs.50441 CGI-04 protein /FL=gb:AF132939.1 gb:NM_015936.1 NM_015936 tyrosyl-tRNA synthetase 2, mitochondrial YARS2 51067 NM_001040436 /// NM_015936 /// XM_005253381 /// XR_242891 /// XR_242892 /// XR_429036 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006437 // tyrosyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from direct assay /// 0070184 // mitochondrial tyrosyl-tRNA aminoacylation // inferred by curator /// 0070184 // mitochondrial tyrosyl-tRNA aminoacylation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // non-traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004831 // tyrosine-tRNA ligase activity // inferred from direct assay /// 0004831 // tyrosine-tRNA ligase activity // non-traceable author statement /// 0004831 // tyrosine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0072545 // tyrosine binding // inferred from direct assay 218471_s_at NM_024649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024649.1 /DEF=Homo sapiens hypothetical protein FLJ23590 (FLJ23590), mRNA. /FEA=mRNA /GEN=FLJ23590 /PROD=hypothetical protein FLJ23590 /DB_XREF=gi:13375892 /UG=Hs.54890 hypothetical protein FLJ23590 /FL=gb:NM_024649.1 NM_024649 Bardet-Biedl syndrome 1 BBS1 582 NM_024649 0001895 // retina homeostasis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0035058 // nonmotile primary cilium assembly // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0005113 // patched binding // inferred from physical interaction /// 0005119 // smoothened binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 218472_s_at NM_015946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015946.1 /DEF=Homo sapiens pelota (Drosophila) homolog (PELO), mRNA. /FEA=mRNA /GEN=PELO /PROD=CGI-17 protein /DB_XREF=gi:7705599 /UG=Hs.5798 pelota (Drosophila) homolog /FL=gb:AF139828.1 gb:AF132951.1 gb:NM_015946.1 NM_015946 pelota homolog (Drosophila) PELO 53918 NM_015946 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042311 // vasodilation // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045123 // cellular extravasation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070481 // nuclear-transcribed mRNA catabolic process, non-stop decay // inferred from electronic annotation /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from electronic annotation /// 0071025 // RNA surveillance // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // inferred from electronic annotation /// 0008305 // integrin complex // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0005518 // collagen binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218473_s_at NM_024656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024656.1 /DEF=Homo sapiens hypothetical protein FLJ22329 (FLJ22329), mRNA. /FEA=mRNA /GEN=FLJ22329 /PROD=hypothetical protein FLJ22329 /DB_XREF=gi:13375904 /UG=Hs.61478 hypothetical protein FLJ22329 /FL=gb:NM_024656.1 NM_024656 collagen beta(1-O)galactosyltransferase 1 COLGALT1 79709 NM_024656 /// XM_005260080 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0050211 // procollagen galactosyltransferase activity // inferred from electronic annotation 218474_s_at NM_018992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018992.1 /DEF=Homo sapiens hypothetical protein (FLJ20040), mRNA. /FEA=mRNA /GEN=FLJ20040 /PROD=hypothetical protein /DB_XREF=gi:9506650 /UG=Hs.61960 hypothetical protein /FL=gb:NM_018992.1 NM_018992 potassium channel tetramerization domain containing 5 KCTD5 54442 NM_018992 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay 218475_at NM_022727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022727.1 /DEF=Homo sapiens HpaII tiny fragments locus 9C (HTF9C), mRNA. /FEA=mRNA /GEN=HTF9C /PROD=HpaII tiny fragments locus 9C /DB_XREF=gi:12232380 /UG=Hs.63609 HpaII tiny fragments locus 9C /FL=gb:NM_022727.1 NM_022727 tRNA methyltransferase 2 homolog A (S. cerevisiae) TRMT2A 27037 NM_001257994 /// NM_022727 /// NM_182984 /// XM_005261234 0001510 // RNA methylation // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218476_at NM_007171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007171.1 /DEF=Homo sapiens protein-O-mannosyltransferase 1 (POMT1), mRNA. /FEA=mRNA /GEN=POMT1 /PROD=protein-O-mannosyltransferase 1 /DB_XREF=gi:6005839 /UG=Hs.99654 protein-O-mannosyltransferase 1 /FL=gb:AF095136.1 gb:NM_007171.1 NM_007171 protein-O-mannosyltransferase 1 POMT1 10585 NM_001077365 /// NM_001077366 /// NM_001136113 /// NM_001136114 /// NM_007171 /// XM_005272156 /// XM_005272158 /// XM_005272159 /// XM_005272162 /// XM_006716932 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0035269 // protein O-linked mannosylation // inferred from electronic annotation /// 0097502 // mannosylation // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation 0000030 // mannosyltransferase activity // traceable author statement /// 0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218477_at NM_014051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014051.1 /DEF=Homo sapiens PTD011 protein (PTD011), mRNA. /FEA=mRNA /GEN=PTD011 /PROD=PTD011 protein /DB_XREF=gi:7662638 /UG=Hs.94896 PTD011 protein /FL=gb:AF078864.1 gb:AF239771.1 gb:NM_014051.1 NM_014051 transmembrane protein 14A TMEM14A 28978 NM_014051 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218478_s_at NM_017612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017612.1 /DEF=Homo sapiens hypothetical protein DKFZp434E2220 (DKFZp434E2220), mRNA. /FEA=mRNA /GEN=DKFZp434E2220 /PROD=hypothetical protein DKFZp434E2220 /DB_XREF=gi:8922133 /UG=Hs.37706 hypothetical protein DKFZp434E2220 /FL=gb:NM_017612.1 NM_017612 zinc finger, CCHC domain containing 8 ZCCHC8 55596 NM_017612 /// XM_005253581 /// XM_006719491 /// XM_006719492 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218479_s_at NM_022459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022459.1 /DEF=Homo sapiens hypothetical protein FLJ13046 similar to exportin 4 (FLJ13046), mRNA. /FEA=mRNA /GEN=FLJ13046 /PROD=hypothetical protein FLJ13046 similar toexportin 4 /DB_XREF=gi:11967998 /UG=Hs.117102 hypothetical protein FLJ13046 similar to exportin 4; KIAA1721 protein /FL=gb:NM_022459.1 NM_022459 exportin 4 XPO4 64328 NM_022459 /// XM_005266502 /// XM_005266503 /// XM_005266504 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218480_at NM_021831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021831.1 /DEF=Homo sapiens hypothetical protein FLJ21839 (FLJ21839), mRNA. /FEA=mRNA /GEN=FLJ21839 /PROD=hypothetical protein FLJ21839 /DB_XREF=gi:11141910 /UG=Hs.285122 hypothetical protein FLJ21839 /FL=gb:NM_021831.1 NM_021831 ATP/GTP binding protein-like 5 AGBL5 60509 NM_001035507 /// NM_021831 /// NR_104246 /// XM_005264477 /// XM_006712058 /// XM_006712059 0006508 // proteolysis // inferred from electronic annotation /// 0035608 // protein deglutamylation // inferred from sequence or structural similarity /// 0035611 // protein branching point deglutamylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218481_at NM_020158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020158.1 /DEF=Homo sapiens exosome component Rrp46 (RRP46), mRNA. /FEA=mRNA /GEN=RRP46 /PROD=exosome component Rrp46 /DB_XREF=gi:9910359 /UG=Hs.283741 exosome component Rrp46 /FL=gb:AF281134.1 gb:NM_020158.1 NM_020158 exosome component 5 EXOSC5 56915 NM_020158 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // non-traceable author statement /// 0006401 // RNA catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0045006 // DNA deamination // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // non-traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035327 // transcriptionally active chromatin // inferred from mutant phenotype 0000175 // 3'-5'-exoribonuclease activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218482_at NM_020189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020189.1 /DEF=Homo sapiens DC6 protein (DC6), mRNA. /FEA=mRNA /GEN=DC6 /PROD=DC6 protein /DB_XREF=gi:9910185 /UG=Hs.283740 DC6 protein /FL=gb:AF201940.1 gb:AF173296.1 gb:NM_020189.1 NM_020189 enhancer of yellow 2 homolog (Drosophila) ENY2 56943 NM_001193557 /// NM_020189 /// NR_036471 /// NR_036472 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0070390 // transcription export complex 2 // inferred from electronic annotation /// 0071819 // DUBm complex // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 218483_s_at NM_020153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020153.1 /DEF=Homo sapiens hypothetical protein (LOC56912), mRNA. /FEA=mRNA /GEN=LOC56912 /PROD=hypothetical protein /DB_XREF=gi:9910357 /UG=Hs.283712 hypothetical protein /FL=gb:AL136934.1 gb:BC001507.1 gb:NM_020153.1 NM_020153 intraflagellar transport 46 homolog (Chlamydomonas) IFT46 56912 NM_001168618 /// NM_020153 /// XM_005271618 0042073 // intraciliary transport // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity 218484_at NM_020142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020142.1 /DEF=Homo sapiens NADH:ubiquinone oxidoreductase MLRQ subunit homolog (LOC56901), mRNA. /FEA=mRNA /GEN=LOC56901 /PROD=NADH:ubiquinone oxidoreductase MLRQ subunithomolog /DB_XREF=gi:10047137 /UG=Hs.110024 NADH:ubiquinone oxidoreductase MLRQ subunit homolog /FL=gb:NM_020142.1 gb:AF164796.1 NM_020142 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 NDUFA4L2 56901 NM_020142 /// XM_005269033 /// XM_005269034 218485_s_at NM_018389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018389.1 /DEF=Homo sapiens hypothetical protein FLJ11320 (FLJ11320), mRNA. /FEA=mRNA /GEN=FLJ11320 /PROD=hypothetical protein FLJ11320 /DB_XREF=gi:8922992 /UG=Hs.12211 hypothetical protein FLJ11320 /FL=gb:BC001427.1 gb:NM_018389.1 NM_018389 solute carrier family 35 (GDP-fucose transporter), member C1 SLC35C1 55343 NM_001145265 /// NM_001145266 /// NM_018389 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218486_at AA149594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA149594 /FEA=EST /DB_XREF=gi:1720413 /DB_XREF=est:zo30d02.s1 /CLONE=IMAGE:588387 /UG=Hs.12229 TGFB inducible early growth response 2 /FL=gb:AF028008.1 gb:NM_003597.1 gb:AF272830.1 AA149594 Kruppel-like factor 11 KLF11 8462 NM_001177716 /// NM_001177718 /// NM_003597 /// XM_005246179 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218487_at BC000977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000977.1 /DEF=Homo sapiens, aminolevulinate, delta-, dehydratase, clone MGC:5057, mRNA, complete cds. /FEA=mRNA /PROD=aminolevulinate, delta-, dehydratase /DB_XREF=gi:12654312 /UG=Hs.1227 aminolevulinate, delta-, dehydratase /FL=gb:BC000977.1 gb:M13928.1 gb:NM_000031.1 BC000977 aminolevulinate dehydratase ALAD 210 NM_000031 /// NM_001003945 /// XM_005251799 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from direct assay /// 0006783 // heme biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004655 // porphobilinogen synthase activity // inferred from direct assay /// 0004655 // porphobilinogen synthase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0032791 // lead ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218488_at NM_020365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020365.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD) (EIF2B3), mRNA. /FEA=mRNA /GEN=EIF2B3 /PROD=eukaryotic translation initiation factor 2B,subunit 3 (gamma, 58kD) /DB_XREF=gi:9966778 /UG=Hs.283627 eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD) /FL=gb:AF257077.1 gb:NM_020365.1 NM_020365 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa EIF2B3 8891 NM_001166588 /// NM_001261418 /// NM_020365 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0032057 // negative regulation of translational initiation in response to stress // inferred from sequence or structural similarity /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 218489_s_at NM_000031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000031.1 /DEF=Homo sapiens aminolevulinate, delta-, dehydratase (ALAD), mRNA. /FEA=mRNA /GEN=ALAD /PROD=delta-aminolevulinic acid dehydratase /DB_XREF=gi:4557296 /UG=Hs.1227 aminolevulinate, delta-, dehydratase /FL=gb:BC000977.1 gb:M13928.1 gb:NM_000031.1 NM_000031 aminolevulinate dehydratase ALAD 210 NM_000031 /// NM_001003945 /// XM_005251799 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from direct assay /// 0006783 // heme biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0004655 // porphobilinogen synthase activity // inferred from direct assay /// 0004655 // porphobilinogen synthase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0032791 // lead ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218490_s_at NM_018443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018443.1 /DEF=Homo sapiens zinc finger protein ZNF140-like protein (LOC55828), mRNA. /FEA=mRNA /GEN=LOC55828 /PROD=zinc finger protein ZNF140-like protein /DB_XREF=gi:8923850 /UG=Hs.125287 zinc finger protein ZNF140-like protein /FL=gb:AF155656.1 gb:NM_018443.1 NM_018443 zinc finger protein 302 ZNF302 55900 NM_001012320 /// NM_001289181 /// NM_001289182 /// NM_001289183 /// NM_001289184 /// NM_001289185 /// NM_001289186 /// NM_001289187 /// NM_001289188 /// NM_001289189 /// NM_001289190 /// NM_001289191 /// NM_001289192 /// NM_018443 /// NM_018675 /// NR_110322 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 218491_s_at NM_014174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014174.1 /DEF=Homo sapiens HSPC144 protein (HSPC144), mRNA. /FEA=mRNA /GEN=HSPC144 /PROD=HSPC144 protein /DB_XREF=gi:7661803 /UG=Hs.13645 HSPC144 protein /FL=gb:AF161493.1 gb:NM_014174.1 NM_014174 thymocyte nuclear protein 1 THYN1 29087 NM_001037304 /// NM_001037305 /// NM_014174 /// NM_199297 /// NM_199298 /// XM_005271527 /// XM_005271528 /// XM_006718827 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 218492_s_at NM_030573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030573.1 /DEF=Homo sapiens hypothetical protein MGC10963 (MGC10963), mRNA. /FEA=mRNA /GEN=MGC10963 /PROD=hypothetical protein MGC10963 /DB_XREF=gi:13386483 /UG=Hs.14927 hypothetical protein MGC10963 /FL=gb:BC004346.1 gb:NM_030573.1 NM_030573 THAP domain containing 7 THAP7 80764 NM_001008695 /// NM_001008696 /// NM_030573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from direct assay 218493_at NM_024571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024571.1 /DEF=Homo sapiens hypothetical protein FLJ22940 (FLJ22940), mRNA. /FEA=mRNA /GEN=FLJ22940 /PROD=hypothetical protein FLJ22940 /DB_XREF=gi:13443017 /UG=Hs.15277 hypothetical protein FLJ22940 /FL=gb:BC001381.1 gb:NM_024571.1 NM_024571 small nuclear ribonucleoprotein 25kDa (U11/U12) SNRNP25 79622 NM_024571 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218494_s_at NM_020062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020062.1 /DEF=Homo sapiens GLUT4 enhancer factor (GEF), mRNA. /FEA=mRNA /GEN=GEF /PROD=GLUT4 enhancer factor /DB_XREF=gi:13236503 /UG=Hs.170088 GLUT4 enhancer factor /FL=gb:AF249267.3 gb:NM_020062.1 NM_020062 SLC2A4 regulator SLC2A4RG 56731 NM_020062 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218495_at NM_004182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004182.1 /DEF=Homo sapiens ubiquitously-expressed transcript (UXT), mRNA. /FEA=mRNA /GEN=UXT /PROD=ubiquitously-expressed transcript /DB_XREF=gi:4759297 /UG=Hs.172791 ubiquitously-expressed transcript /FL=gb:BC000720.1 gb:AF092737.1 gb:NM_004182.1 gb:AF083241.1 gb:AF083242.1 NM_004182 ubiquitously-expressed, prefoldin-like chaperone UXT 8409 NM_004182 /// NM_153477 /// NR_045559 /// NR_045560 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016272 // prefoldin complex // inferred from electronic annotation 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 218496_at BG534527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG534527 /FEA=EST /DB_XREF=gi:13526067 /DB_XREF=est:602553771F1 /CLONE=IMAGE:4663504 /UG=Hs.178655 ribonuclease H1 /FL=gb:BC002973.1 gb:AF048994.1 gb:AF048995.1 gb:AF039652.1 gb:NM_002936.1 BG534527 ribonuclease H1 RNASEH1 246243 NM_001286834 /// NM_001286837 /// NM_002936 /// XR_244873 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218497_s_at NM_002936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002936.1 /DEF=Homo sapiens ribonuclease H1 (RNASEH1), mRNA. /FEA=mRNA /GEN=RNASEH1 /PROD=ribonuclease H1 /DB_XREF=gi:4506554 /UG=Hs.178655 ribonuclease H1 /FL=gb:BC002973.1 gb:AF048994.1 gb:AF048995.1 gb:AF039652.1 gb:NM_002936.1 NM_002936 ribonuclease H1 RNASEH1 246243 NM_001286834 /// NM_001286837 /// NM_002936 /// XR_244873 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218498_s_at NM_014584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014584.1 /DEF=Homo sapiens ERO1 (S. cerevisiae)-like (ERO1L), mRNA. /FEA=mRNA /GEN=ERO1L /PROD=ERO1 (S. cerevisiae)-like /DB_XREF=gi:7657068 /UG=Hs.25740 ERO1 (S. cerevisiae)-like /FL=gb:AF081886.1 gb:NM_014584.1 NM_014584 ERO1-like (S. cerevisiae) ERO1L 30001 NM_014584 0006457 // protein folding // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009266 // response to temperature stimulus // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 218499_at NM_016542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016542.1 /DEF=Homo sapiens serinethreonine protein kinase MASK (LOC51765), mRNA. /FEA=mRNA /GEN=LOC51765 /PROD=serinethreonine protein kinase MASK /DB_XREF=gi:7706568 /UG=Hs.23643 serinethreonine protein kinase MASK /FL=gb:AB040057.1 gb:NM_016542.1 NM_016542 serine/threonine protein kinase MST4 MST4 51765 NM_001042452 /// NM_001042453 /// NM_016542 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0045595 // regulation of cell differentiation // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218500_at NM_016647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016647.1 /DEF=Homo sapiens mesenchymal stem cell protein DSCD75 (LOC51337), mRNA. /FEA=mRNA /GEN=LOC51337 /PROD=mesenchymal stem cell protein DSCD75 /DB_XREF=gi:7706199 /UG=Hs.25237 mesenchymal stem cell protein DSCD75 /FL=gb:BC001311.1 gb:AF242773.1 gb:NM_016647.1 NM_016647 thioesterase superfamily member 6 THEM6 51337 NM_016647 /// XM_005250955 0005576 // extracellular region // inferred from electronic annotation 218501_at NM_019555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019555.1 /DEF=Homo sapiens Rho guanine nucleotide exchange factor (GEF) 3 (ARHGEF3), mRNA. /FEA=mRNA /GEN=ARHGEF3 /PROD=Rho guanine nucleotide exchange factor (GEF) 3 /DB_XREF=gi:9506400 /UG=Hs.25951 Rho guanine nucleotide exchange factor (GEF) 3 /FL=gb:AF249744.1 gb:NM_019555.1 NM_019555 Rho guanine nucleotide exchange factor (GEF) 3 ARHGEF3 50650 NM_001128615 /// NM_001128616 /// NM_001289698 /// NM_019555 /// XM_005265186 /// XM_005265187 /// XM_005265188 /// XM_005265189 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 218502_s_at NM_014112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014112.1 /DEF=Homo sapiens trichorhinophalangeal syndrome I gene (TRPS1), mRNA. /FEA=mRNA /GEN=TRPS1 /PROD=trichorhinophalangeal syndrome I gene /DB_XREF=gi:7657658 /UG=Hs.26102 trichorhinophalangeal syndrome I /FL=gb:AF183810.1 gb:NM_014112.1 NM_014112 trichorhinophalangeal syndrome I TRPS1 7227 NM_001282902 /// NM_001282903 /// NM_014112 /// XM_005251049 /// XM_006716624 /// XM_006716625 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218503_at NM_017794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017794.1 /DEF=Homo sapiens hypothetical protein FLJ20375 (FLJ20375), mRNA. /FEA=mRNA /GEN=FLJ20375 /PROD=hypothetical protein FLJ20375 /DB_XREF=gi:8923357 /UG=Hs.274251 hypothetical protein FLJ20375 /FL=gb:BC001246.1 gb:NM_017794.1 NM_017794 focadhesin FOCAD 54914 NM_017794 /// XM_005251494 /// XM_006716794 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218504_at NM_016044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016044.1 /DEF=Homo sapiens CGI-105 protein (LOC51011), mRNA. /FEA=mRNA /GEN=LOC51011 /PROD=CGI-105 protein /DB_XREF=gi:7705607 /UG=Hs.279932 CGI-105 protein /FL=gb:AF151863.1 gb:NM_016044.1 NM_016044 fumarylacetoacetate hydrolase domain containing 2A FAHD2A 51011 NM_016044 /// XM_006712560 /// XM_006712561 /// XM_006712562 /// XM_006712563 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218505_at NM_024673 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024673.1 /DEF=Homo sapiens hypothetical protein FLJ12270 (FLJ12270), mRNA. /FEA=mRNA /GEN=FLJ12270 /PROD=hypothetical protein FLJ12270 /DB_XREF=gi:13375935 /UG=Hs.85969 hypothetical protein FLJ12270 /FL=gb:NM_024673.1 NM_024673 WD repeat domain 59 WDR59 79726 NM_030581 /// XM_005256146 /// XM_005256147 0005515 // protein binding // inferred from electronic annotation 218506_x_at NM_018459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018459.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM045 (BM045), mRNA. /FEA=mRNA /GEN=BM045 /PROD=uncharacterized bone marrow protein BM045 /DB_XREF=gi:8922103 /UG=Hs.8750 uncharacterized bone marrow protein BM045 /FL=gb:AF217521.1 gb:NM_018459.1 NM_018459 glyoxylate reductase 1 homolog (Arabidopsis) GLYR1 84656 NM_032569 /// XM_005255637 /// XM_005255638 /// XM_005255639 /// XM_005255640 /// XR_243321 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 218507_at NM_013332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013332.1 /DEF=Homo sapiens hypoxia-inducible protein 2 (HIG2), mRNA. /FEA=mRNA /GEN=HIG2 /PROD=hypoxia-inducible protein 2 /DB_XREF=gi:7019408 /UG=Hs.61762 hypoxia-inducible protein 2 /FL=gb:BC001863.1 gb:AF144755.1 gb:NM_013332.1 NM_013332 hypoxia inducible lipid droplet-associated HILPDA 29923 NM_001098786 /// NM_013332 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0006950 // response to stress // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010884 // positive regulation of lipid storage // inferred from direct assay /// 0035425 // autocrine signaling // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 218508_at NM_018403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018403.1 /DEF=Homo sapiens transcription factor (SMIF gene) (HSA275986), mRNA. /FEA=mRNA /GEN=HSA275986 /PROD=transcription factor (SMIF gene) /DB_XREF=gi:8923766 /UG=Hs.71414 transcription factor (SMIF gene) /FL=gb:NM_018403.1 NM_018403 decapping mRNA 1A DCP1A 55802 NM_001290204 /// NM_001290205 /// NM_001290206 /// NM_001290207 /// NM_018403 /// XM_005265320 /// XM_005278359 /// XM_005278360 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 218509_at NM_022737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022737.1 /DEF=Homo sapiens hypothetical protein FLJ13055 (FLJ13055), mRNA. /FEA=mRNA /GEN=FLJ13055 /PROD=hypothetical protein FLJ13055 /DB_XREF=gi:12232394 /UG=Hs.6846 hypothetical protein FLJ13055 /FL=gb:NM_022737.1 NM_022737 lipid phosphate phosphatase-related protein type 2 LPPR2 64748 NM_001170635 /// NM_022737 /// XM_005260017 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218510_x_at AI816291 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI816291 /FEA=EST /DB_XREF=gi:5431837 /DB_XREF=est:au46f08.x1 /CLONE=IMAGE:2517831 /UG=Hs.82273 hypothetical protein /FL=gb:NM_019000.1 AI816291 family with sequence similarity 134, member B FAM134B 54463 NM_001034850 /// NM_019000 /// XM_005248312 0019233 // sensory perception of pain // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218511_s_at NM_018129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018129.1 /DEF=Homo sapiens hypothetical protein FLJ10535 (FLJ10535), mRNA. /FEA=mRNA /GEN=FLJ10535 /PROD=hypothetical protein FLJ10535 /DB_XREF=gi:8922497 /UG=Hs.267963 hypothetical protein FLJ10535 /FL=gb:NM_018129.1 NM_018129 pyridoxamine 5'-phosphate oxidase PNPO 55163 NM_018129 /// XM_005257500 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008615 // pyridoxine biosynthetic process // inferred from electronic annotation /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0042823 // pyridoxal phosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004733 // pyridoxamine-phosphate oxidase activity // traceable author statement /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016638 // oxidoreductase activity, acting on the CH-NH2 group of donors // inferred from electronic annotation 218512_at NM_018256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018256.1 /DEF=Homo sapiens hypothetical protein FLJ10881 (FLJ10881), mRNA. /FEA=mRNA /GEN=FLJ10881 /PROD=hypothetical protein FLJ10881 /DB_XREF=gi:8922736 /UG=Hs.73291 hypothetical protein FLJ10881 /FL=gb:AF242546.1 gb:NM_018256.1 NM_018256 WD repeat domain 12 WDR12 55759 NM_018256 0000463 // maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0000466 // maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042273 // ribosomal large subunit biogenesis // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030687 // preribosome, large subunit precursor // inferred from direct assay /// 0070545 // PeBoW complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation 218513_at NM_018352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018352.1 /DEF=Homo sapiens hypothetical protein FLJ11184 (FLJ11184), mRNA. /FEA=mRNA /GEN=FLJ11184 /PROD=hypothetical protein FLJ11184 /DB_XREF=gi:8922922 /UG=Hs.267446 hypothetical protein FLJ11184 /FL=gb:NM_018352.1 NM_018352 translation machinery associated 16 homolog (S. cerevisiae) TMA16 55319 NM_018352 0005634 // nucleus // inferred from direct assay 218514_at NM_018149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018149.1 /DEF=Homo sapiens hypothetical protein FLJ10587 (FLJ10587), mRNA. /FEA=mRNA /GEN=FLJ10587 /PROD=hypothetical protein FLJ10587 /DB_XREF=gi:8922539 /UG=Hs.7296 hypothetical protein FLJ10587 /FL=gb:NM_018149.1 NM_018149 SMG8 nonsense mediated mRNA decay factor SMG8 55181 NM_018149 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from mutant phenotype 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 218515_at NM_016631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016631.1 /DEF=Homo sapiens hypothetical protein (LOC51325), mRNA. /FEA=mRNA /GEN=LOC51325 /PROD=hypothetical protein /DB_XREF=gi:7706175 /UG=Hs.26461 hypothetical protein /FL=gb:AF208862.1 gb:NM_016631.1 NM_016631 PAX3 and PAX7 binding protein 1 PAXBP1 94104 NM_013329 /// NM_016631 /// NM_058191 /// NM_145328 /// NR_027873 /// XM_006724066 /// XM_006724067 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0014842 // regulation of satellite cell proliferation // inferred from electronic annotation /// 0031062 // positive regulation of histone methylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation 218516_s_at NM_017813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017813.1 /DEF=Homo sapiens hypothetical protein FLJ20421 (FLJ20421), mRNA. /FEA=mRNA /GEN=FLJ20421 /PROD=hypothetical protein FLJ20421 /DB_XREF=gi:8923391 /UG=Hs.263727 hypothetical protein FLJ20421 /FL=gb:NM_017813.1 NM_017813 inositol monophosphatase domain containing 1 IMPAD1 54928 NM_017813 0001501 // skeletal system development // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030204 // chondroitin sulfate metabolic process // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008254 // 3'-nucleotidase activity // inferred from electronic annotation /// 0008441 // 3'(2'),5'-bisphosphate nucleotidase activity // inferred from electronic annotation /// 0008934 // inositol monophosphate 1-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation 218517_at NM_024900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024900.1 /DEF=Homo sapiens hypothetical protein FLJ22479 (FLJ22479), mRNA. /FEA=mRNA /GEN=FLJ22479 /PROD=hypothetical protein FLJ22479 /DB_XREF=gi:13376356 /UG=Hs.238246 hypothetical protein FLJ22479 /FL=gb:NM_024900.1 NM_024900 jade family PHD finger 1 JADE1 79960 NM_001287437 /// NM_001287439 /// NM_001287440 /// NM_001287441 /// NM_001287442 /// NM_001287443 /// NM_024900 /// NM_199320 /// XM_005263229 /// XM_005263232 /// XM_006714310 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0001105 // RNA polymerase II transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218518_at NM_016603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016603.1 /DEF=Homo sapiens GAP-like protein (LOC51306), mRNA. /FEA=mRNA /GEN=LOC51306 /PROD=GAP-like protein /DB_XREF=gi:7706136 /UG=Hs.82035 potential nuclear protein C5ORF5; GAP-like protein /FL=gb:AF251038.1 gb:AF157316.1 gb:NM_016603.1 NM_016603 family with sequence similarity 13, member B FAM13B 51306 NM_001101800 /// NM_001101801 /// NM_016603 /// XM_005272007 /// XM_006714647 /// XM_006714648 /// XM_006714649 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 218519_at NM_017945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017945.1 /DEF=Homo sapiens hypothetical protein FLJ20730 (FLJ20730), mRNA. /FEA=mRNA /GEN=FLJ20730 /PROD=hypothetical protein FLJ20730 /DB_XREF=gi:8923656 /UG=Hs.237480 hypothetical protein FLJ20730 /FL=gb:BC005207.1 gb:NM_017945.1 NM_017945 solute carrier family 35, member A5 SLC35A5 55032 NM_017945 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation 218520_at NM_013254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013254.1 /DEF=Homo sapiens TANK-binding kinase 1 (TBK1), mRNA. /FEA=mRNA /GEN=TBK1 /PROD=TANK-binding kinase 1 /DB_XREF=gi:7019546 /UG=Hs.21712 TANK-binding kinase 1 /FL=gb:AF191838.1 gb:NM_013254.1 gb:AF174536.1 NM_013254 TANK-binding kinase 1 TBK1 29110 NM_013254 /// XM_005268809 /// XM_005268810 0002218 // activation of innate immune response // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032606 // type I interferon production // traceable author statement /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // non-traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 218521_s_at NM_018299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018299.1 /DEF=Homo sapiens hypothetical protein FLJ11011 (FLJ11011), mRNA. /FEA=mRNA /GEN=FLJ11011 /PROD=hypothetical protein FLJ11011 /DB_XREF=gi:8922821 /UG=Hs.21275 hypothetical protein FLJ11011 /FL=gb:NM_018299.1 NM_018299 ubiquitin-conjugating enzyme E2W (putative) UBE2W 55284 NM_001001481 /// NM_001001482 /// NM_001271015 /// NM_018299 /// NR_073119 /// NR_073120 /// NR_073121 0006281 // DNA repair // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071218 // cellular response to misfolded protein // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 218522_s_at NM_018174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018174.1 /DEF=Homo sapiens hypothetical protein FLJ10669 (FLJ10669), mRNA. /FEA=mRNA /GEN=FLJ10669 /PROD=hypothetical protein FLJ10669 /DB_XREF=gi:8922582 /UG=Hs.66048 hypothetical protein FLJ10669 /FL=gb:NM_018174.1 NM_018174 microtubule-associated protein 1S MAP1S 55201 NM_018174 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0047497 // mitochondrion transport along microtubule // traceable author statement /// 0048812 // neuron projection morphogenesis // inferred from expression pattern /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0015631 // tubulin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 218523_at NM_022126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022126.1 /DEF=Homo sapiens phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP), mRNA. /FEA=mRNA /GEN=LHPP /PROD=phospholysine phosphohistidine inorganicpyrophosphate phosphatase /DB_XREF=gi:11545850 /UG=Hs.20950 phospholysine phosphohistidine inorganic pyrophosphate phosphatase /FL=gb:AB049629.1 gb:NM_022126.1 NM_022126 phospholysine phosphohistidine inorganic pyrophosphate phosphatase LHPP 64077 NM_001167880 /// NM_022126 /// XM_005270025 /// XM_005270026 /// XM_005270027 /// XM_006717943 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004427 // inorganic diphosphatase activity // inferred from direct assay /// 0008969 // phosphohistidine phosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218524_at NM_004424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004424.2 /DEF=Homo sapiens E4F transcription factor 1 (E4F1), mRNA. /FEA=mRNA /GEN=E4F1 /PROD=p120E4F /DB_XREF=gi:10938012 /UG=Hs.154196 E4F transcription factor 1 /FL=gb:NM_004424.2 gb:U87269.1 NM_004424 E4F transcription factor 1 E4F1 1877 NM_001288776 /// NM_001288778 /// NM_004424 /// XM_005255155 /// XM_005255156 /// XM_006720857 /// XM_006720858 /// XR_243266 /// XR_429636 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0009794 // regulation of mitotic cell cycle, embryonic // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred by curator /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0035497 // cAMP response element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218525_s_at NM_017902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017902.1 /DEF=Homo sapiens hypothetical protein FLJ20615 (FLJ20615), mRNA. /FEA=mRNA /GEN=FLJ20615 /PROD=hypothetical protein FLJ20615 /DB_XREF=gi:8923568 /UG=Hs.14595 hypothetical protein FLJ20615 /FL=gb:NM_017902.1 NM_017902 hypoxia inducible factor 1, alpha subunit inhibitor HIF1AN 55662 NM_017902 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0036138 // peptidyl-histidine hydroxylation // inferred from direct assay /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from direct assay /// 0042265 // peptidyl-asparagine hydroxylation // inferred from direct assay /// 0042265 // peptidyl-asparagine hydroxylation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 2001214 // positive regulation of vasculogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005112 // Notch binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // not recorded /// 0019826 // oxygen sensor activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0036139 // peptidyl-histidine dioxygenase activity // inferred from direct assay /// 0036140 // peptidyl-asparagine 3-dioxygenase activity // inferred from direct assay /// 0036140 // peptidyl-asparagine 3-dioxygenase activity // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071532 // ankyrin repeat binding // inferred from physical interaction 218526_s_at NM_014185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014185.1 /DEF=Homo sapiens HSPC165 protein (HSPC165), mRNA. /FEA=mRNA /GEN=HSPC165 /PROD=HSPC165 protein /DB_XREF=gi:7661825 /UG=Hs.13605 HSPC165 protein /FL=gb:AF161514.1 gb:AF151070.1 gb:NM_014185.1 gb:NM_016492.1 gb:AF168714.1 gb:AF265206.1 NM_014185 RAN guanine nucleotide release factor RANGRF 29098 NM_001177801 /// NM_001177802 /// NM_016492 /// XM_005256618 0002027 // regulation of heart rate // traceable author statement /// 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0003254 // regulation of membrane depolarization // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 1900825 // regulation of membrane depolarization during cardiac muscle cell action potential // traceable author statement /// 1902305 // regulation of sodium ion transmembrane transport // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // inferred from mutant phenotype /// 2000010 // positive regulation of protein localization to cell surface // inferred from direct assay /// 2000010 // positive regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred by curator /// 0005901 // caveola // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from sequence or structural similarity /// 0008565 // protein transporter activity // inferred from mutant phenotype /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from physical interaction 218527_at NM_017692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017692.1 /DEF=Homo sapiens hypothetical protein FLJ20157 (FLJ20157), mRNA. /FEA=mRNA /GEN=FLJ20157 /PROD=hypothetical protein FLJ20157 /DB_XREF=gi:8923155 /UG=Hs.14394 hypothetical protein FLJ20157 /FL=gb:BC001628.1 gb:NM_017692.1 NM_017692 aprataxin APTX 54840 NM_001195248 /// NM_001195249 /// NM_001195250 /// NM_001195251 /// NM_001195252 /// NM_001195254 /// NM_017692 /// NM_175069 /// NM_175072 /// NM_175073 /// NR_036576 /// NR_036577 /// NR_036578 /// NR_036579 /// XM_006716791 /// XM_006716792 /// XR_428423 0000012 // single strand break repair // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0098506 // polynucleotide 3' dephosphorylation // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008967 // phosphoglycolate phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033699 // DNA 5'-adenosine monophosphate hydrolase activity // inferred from direct assay /// 0046403 // polynucleotide 3'-phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction 218528_s_at NM_022781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022781.1 /DEF=Homo sapiens hypothetical protein FLJ21343 (FLJ21343), mRNA. /FEA=mRNA /GEN=FLJ21343 /PROD=hypothetical protein FLJ21343 /DB_XREF=gi:12232470 /UG=Hs.77823 hypothetical protein FLJ21343 /FL=gb:AL136817.1 gb:NM_022781.1 NM_022781 ring finger protein 38 RNF38 152006 NM_022781 /// NM_194328 /// NM_194329 /// NM_194330 /// NM_194331 /// NM_194332 /// XM_005251364 /// XM_005251365 /// XM_005251366 /// XM_005251367 /// XM_005251368 /// XM_006716721 0008584 // male gonad development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0036126 // sperm flagellum // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218529_at NM_016579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016579.1 /DEF=Homo sapiens 8D6 antigen (LOC51293), mRNA. /FEA=mRNA /GEN=LOC51293 /PROD=8D6 antigen /DB_XREF=gi:7706110 /UG=Hs.106196 8D6 antigen /FL=gb:AL136652.1 gb:BC000668.1 gb:AF161254.1 gb:NM_016579.1 NM_016579 CD320 molecule CD320 51293 NM_001165895 /// NM_016579 0001558 // regulation of cell growth // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009235 // cobalamin metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from direct assay 218530_at NM_013241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013241.1 /DEF=Homo sapiens FH1FH2 domain-containing protein (FHOS), mRNA. /FEA=mRNA /GEN=FHOS /PROD=FH1FH2 domain-containing protein /DB_XREF=gi:7019374 /UG=Hs.95231 FH1FH2 domain-containing protein /FL=gb:AF113615.1 gb:NM_013241.1 NM_013241 formin homology 2 domain containing 1 FHOD1 29109 NM_013241 /// XM_005255909 /// XM_005255910 /// XM_006721180 0007015 // actin filament organization // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218531_at NM_025124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025124.1 /DEF=Homo sapiens hypothetical protein FLJ21749 (FLJ21749), mRNA. /FEA=mRNA /GEN=FLJ21749 /PROD=hypothetical protein FLJ21749 /DB_XREF=gi:13376700 /UG=Hs.288761 hypothetical protein FLJ21749 /FL=gb:NM_025124.1 NM_025124 transmembrane protein 134 TMEM134 80194 NM_001078650 /// NM_001078651 /// NM_025124 /// NR_073409 /// NR_073410 /// NR_073411 /// NR_073412 /// NR_073413 /// XM_006718693 /// XR_428924 /// XR_428925 /// XR_428926 /// XR_428927 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218532_s_at NM_019000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019000.1 /DEF=Homo sapiens hypothetical protein (FLJ20152), mRNA. /FEA=mRNA /GEN=FLJ20152 /PROD=hypothetical protein /DB_XREF=gi:9506660 /UG=Hs.82273 hypothetical protein /FL=gb:NM_019000.1 NM_019000 family with sequence similarity 134, member B FAM134B 54463 NM_001034850 /// NM_019000 /// XM_005248312 0019233 // sensory perception of pain // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218533_s_at NM_017859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017859.1 /DEF=Homo sapiens hypothetical protein FLJ20517 (FLJ20517), mRNA. /FEA=mRNA /GEN=FLJ20517 /PROD=hypothetical protein FLJ20517 /DB_XREF=gi:8923486 /UG=Hs.39850 hypothetical protein FLJ20517 /FL=gb:NM_017859.1 NM_017859 uridine-cytidine kinase 1-like 1 UCKL1 54963 NM_001193379 /// NM_017859 /// XM_005260216 /// XM_006723806 /// XM_006723807 /// XM_006723808 /// XM_006723809 /// XM_006723810 /// XM_006723811 /// XM_006723812 /// XM_006723813 /// XR_244120 /// XR_244121 /// XR_430299 /// XR_430300 /// XR_430301 /// XR_430302 /// XR_430303 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044206 // UMP salvage // inferred from electronic annotation /// 0044211 // CTP salvage // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004849 // uridine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 218534_s_at NM_018046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018046.1 /DEF=Homo sapiens hypothetical protein FLJ10283 (FLJ10283), mRNA. /FEA=mRNA /GEN=FLJ10283 /PROD=hypothetical protein FLJ10283 /DB_XREF=gi:8922325 /UG=Hs.284216 hypothetical protein FLJ10283 /FL=gb:NM_018046.1 NM_018046 angiogenic factor with G patch and FHA domains 1 AGGF1 55109 NM_018046 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218535_s_at NM_018343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018343.1 /DEF=Homo sapiens hypothetical protein FLJ11159 (FLJ11159), mRNA. /FEA=mRNA /GEN=FLJ11159 /PROD=hypothetical protein FLJ11159 /DB_XREF=gi:8922904 /UG=Hs.27021 hypothetical protein FLJ11159 /FL=gb:BC000953.2 gb:NM_018343.1 NM_018343 RIO kinase 2 RIOK2 55781 NM_001159749 /// NM_018343 /// XM_006714657 0006468 // protein phosphorylation // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 218536_at AF052167 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF052167.1 /DEF=Homo sapiens clone 24749 and 24750 mRNA sequences. /FEA=mRNA /DB_XREF=gi:3360478 /UG=Hs.30057 transporter similar to yeast MRS2 /FL=gb:NM_020662.1 gb:AF288288.1 AF052167 MRS2 magnesium transporter MRS2 57380 NM_001286264 /// NM_001286265 /// NM_001286266 /// NM_020662 /// NR_104423 /// XM_005249242 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 218537_at NM_017885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017885.1 /DEF=Homo sapiens hypothetical protein FLJ20568 (FLJ20568), mRNA. /FEA=mRNA /GEN=FLJ20568 /PROD=hypothetical protein FLJ20568 /DB_XREF=gi:8923535 /UG=Hs.279581 hypothetical protein FLJ20568 /FL=gb:NM_017885.1 NM_017885 host cell factor C1 regulator 1 (XPO1 dependent) HCFC1R1 54985 NM_001002017 /// NM_001002018 /// NM_001288665 /// NM_001288666 /// NM_001288667 /// NM_001288668 /// NM_017885 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 218538_s_at NM_020662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020662.1 /DEF=Homo sapiens transporter similar to yeast MRS2 (MRS2L), mRNA. /FEA=mRNA /GEN=MRS2L /PROD=transporter similar to yeast MRS2 /DB_XREF=gi:10190701 /UG=Hs.30057 transporter similar to yeast MRS2 /FL=gb:NM_020662.1 gb:AF288288.1 NM_020662 MRS2 magnesium transporter MRS2 57380 NM_001286264 /// NM_001286265 /// NM_001286266 /// NM_020662 /// NR_104423 /// XM_005249242 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 218539_at NM_017943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017943.1 /DEF=Homo sapiens hypothetical protein FLJ20725 (FLJ20725), mRNA. /FEA=mRNA /GEN=FLJ20725 /PROD=hypothetical protein FLJ20725 /DB_XREF=gi:8923650 /UG=Hs.15467 hypothetical protein FLJ20725 /FL=gb:NM_017943.1 NM_017943 F-box protein 34 FBXO34 55030 NM_017943 /// NM_152231 /// XM_005267791 /// XM_006720185 0005515 // protein binding // inferred from electronic annotation 218540_at NM_024328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024328.1 /DEF=Homo sapiens hypothetical protein MGC2652 (MGC2652), mRNA. /FEA=mRNA /GEN=MGC2652 /PROD=hypothetical protein MGC2652 /DB_XREF=gi:13236576 /UG=Hs.15098 hypothetical protein MGC2652 /FL=gb:BC002984.1 gb:NM_024328.1 NM_024328 thiamine triphosphatase THTPA 79178 NM_001126339 /// NM_001256062 /// NM_001256321 /// NM_001256322 /// NM_001256323 /// NM_024328 /// NR_023314 /// NR_046051 /// NR_046052 0006091 // generation of precursor metabolites and energy // non-traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006772 // thiamine metabolic process // traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0042357 // thiamine diphosphate metabolic process // inferred from sequence or structural similarity /// 0042723 // thiamine-containing compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050333 // thiamin-triphosphatase activity // inferred from direct assay /// 0050333 // thiamin-triphosphatase activity // traceable author statement 218541_s_at NM_020130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020130.1 /DEF=Homo sapiens chromosome 8 open reading frame 4 (C8ORF4), mRNA. /FEA=mRNA /GEN=C8ORF4 /PROD=chromosome 8 open reading frame 4 /DB_XREF=gi:9910147 /UG=Hs.283683 chromosome 8 open reading frame 4 /FL=gb:AF268037.1 gb:NM_020130.1 NM_020130 chromosome 8 open reading frame 4 C8orf4 56892 NM_020130 0006915 // apoptotic process // inferred from electronic annotation 218542_at NM_018131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018131.1 /DEF=Homo sapiens hypothetical protein FLJ10540 (FLJ10540), mRNA. /FEA=mRNA /GEN=FLJ10540 /PROD=hypothetical protein FLJ10540 /DB_XREF=gi:8922501 /UG=Hs.14559 hypothetical protein FLJ10540 /FL=gb:NM_018131.1 NM_018131 centrosomal protein 55kDa CEP55 55165 NM_001127182 /// NM_018131 /// XM_006717909 0000281 // mitotic cytokinesis // inferred from genetic interaction /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218543_s_at NM_022750 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022750.1 /DEF=Homo sapiens hypothetical protein FLJ22693 (FLJ22693), mRNA. /FEA=mRNA /GEN=FLJ22693 /PROD=hypothetical protein FLJ22693 /DB_XREF=gi:12232412 /UG=Hs.12646 hypothetical protein FLJ22693 /FL=gb:AL136766.1 gb:NM_022750.1 NM_022750 poly (ADP-ribose) polymerase family, member 12 PARP12 64761 NM_022750 /// XM_005250038 /// XM_005250039 /// XM_005250040 /// XR_242188 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218544_s_at NM_005772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005772.1 /DEF=Homo sapiens RNA cyclase homolog (RNAC), mRNA. /FEA=mRNA /GEN=RNAC /PROD=RNA cyclase homolog /DB_XREF=gi:5032042 /UG=Hs.113052 RNA cyclase homolog /FL=gb:BC001025.1 gb:AF067172.1 gb:NM_005772.1 NM_005772 RNA terminal phosphate cyclase-like 1 RCL1 10171 NM_001286699 /// NM_001286700 /// NM_001286701 /// NM_005772 /// XM_006716715 0006396 // RNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003963 // RNA-3'-phosphate cyclase activity // non-traceable author statement 218545_at NM_018318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018318.1 /DEF=Homo sapiens hypothetical protein FLJ11088 (FLJ11088), mRNA. /FEA=mRNA /GEN=FLJ11088 /PROD=hypothetical protein FLJ11088 /DB_XREF=gi:8922858 /UG=Hs.49282 hypothetical protein FLJ11088 /FL=gb:NM_018318.1 NM_018318 coiled-coil domain containing 91 CCDC91 55297 NM_018318 /// XM_005253413 /// XM_005253414 /// XM_005253415 /// XM_005253416 /// XM_006719103 /// XM_006719104 /// XM_006719105 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0042802 // identical protein binding // inferred from electronic annotation 218546_at NM_024709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024709.1 /DEF=Homo sapiens hypothetical protein FLJ14146 (FLJ14146), mRNA. /FEA=mRNA /GEN=FLJ14146 /PROD=hypothetical protein FLJ14146 /DB_XREF=gi:13376004 /UG=Hs.103395 hypothetical protein FLJ14146 /FL=gb:NM_024709.1 NM_024709 chromosome 1 open reading frame 115 C1orf115 79762 NM_024709 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218547_at NM_024887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024887.1 /DEF=Homo sapiens hypothetical protein FLJ13102 (FLJ13102), mRNA. /FEA=mRNA /GEN=FLJ13102 /PROD=hypothetical protein FLJ13102 /DB_XREF=gi:13376336 /UG=Hs.225160 hypothetical protein FLJ13102 /FL=gb:BC003643.1 gb:NM_024887.1 NM_024887 dehydrodolichyl diphosphate synthase DHDDS 79947 NM_001243564 /// NM_001243565 /// NM_024887 /// NM_205861 /// XM_006710912 /// XM_006710913 /// XM_006710914 /// XM_006710915 /// XM_006710916 /// XM_006710917 /// XM_006710918 /// XM_006710919 /// XM_006710920 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016765 // transferase activity, transferring alkyl or aryl (other than methyl) groups // inferred from electronic annotation 218548_x_at NM_015926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015926.1 /DEF=Homo sapiens putative secreted protein (SIG11), mRNA. /FEA=mRNA /GEN=SIG11 /PROD=putative secreted protein /DB_XREF=gi:7706707 /UG=Hs.279785 putative secreted protein /FL=gb:AF072733.1 gb:NM_015926.1 NM_015926 testis expressed 264 TEX264 51368 NM_001129884 /// NM_001243725 /// NM_001243726 /// NM_001243727 /// NM_001278195 /// NM_015926 /// NR_024012 /// NR_103462 /// NR_103463 /// XM_006713195 /// XM_006713196 /// XM_006713197 /// XM_006713198 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 218549_s_at NM_016033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016033.1 /DEF=Homo sapiens CGI-90 protein (LOC51115), mRNA. /FEA=mRNA /GEN=LOC51115 /PROD=CGI-90 protein /DB_XREF=gi:7705802 /UG=Hs.44222 CGI-90 protein /FL=gb:AF151848.1 gb:NM_016033.1 NM_016033 regulator of microtubule dynamics 1 RMDN1 51115 NM_001286707 /// NM_001286719 /// NM_016033 /// XM_005250944 /// XM_005250945 /// XM_005250946 /// XM_005250947 /// XM_005250948 /// XM_005250950 /// XM_006716573 /// XM_006716574 /// XM_006716575 /// XM_006716576 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 218550_s_at NM_018205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018205.1 /DEF=Homo sapiens hypothetical protein FLJ10751 (FLJ10751), mRNA. /FEA=mRNA /GEN=FLJ10751 /PROD=hypothetical protein FLJ10751 /DB_XREF=gi:8922643 /UG=Hs.7778 hypothetical protein FLJ10751 /FL=gb:NM_018205.1 NM_018205 leucine rich repeat containing 20 LRRC20 55222 NM_001278211 /// NM_001278212 /// NM_001278213 /// NM_001278214 /// NM_018205 /// NM_018239 /// NM_207119 /// NR_103467 /// NR_103468 0005515 // protein binding // inferred from electronic annotation 218551_at NM_021933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021933.1 /DEF=Homo sapiens hypothetical protein FLJ12438 (FLJ12438), mRNA. /FEA=mRNA /GEN=FLJ12438 /PROD=hypothetical protein FLJ12438 /DB_XREF=gi:11345471 /UG=Hs.8595 hypothetical protein FLJ12438 /FL=gb:NM_021933.1 NM_021933 migration and invasion inhibitory protein MIIP 60672 NM_001025374 /// NM_021933 /// XM_005263487 218552_at NM_018281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018281.1 /DEF=Homo sapiens hypothetical protein FLJ10948 (FLJ10948), mRNA. /FEA=mRNA /GEN=FLJ10948 /PROD=hypothetical protein FLJ10948 /DB_XREF=gi:8922786 /UG=Hs.9670 hypothetical protein FLJ10948 /FL=gb:NM_018281.1 NM_018281 enoyl CoA hydratase domain containing 2 ECHDC2 55268 NM_001198961 /// NM_001198962 /// NM_018281 /// XM_005271002 /// XM_006710739 /// XM_006710740 /// XM_006710741 /// XM_006710742 /// XM_006710743 /// XM_006710744 /// XM_006710745 /// XM_006710746 /// XM_006710747 /// XM_006710748 /// XM_006710749 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 218553_s_at NM_024076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024076.1 /DEF=Homo sapiens hypothetical protein MGC2628 (MGC2628), mRNA. /FEA=mRNA /GEN=MGC2628 /PROD=hypothetical protein MGC2628 /DB_XREF=gi:13129063 /UG=Hs.171637 hypothetical protein MGC2628 /FL=gb:BC001185.1 gb:NM_024076.1 NM_024076 potassium channel tetramerization domain containing 15 KCTD15 79047 NM_001129994 /// NM_001129995 /// NM_024076 0007275 // multicellular organismal development // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218554_s_at NM_018489 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018489.1 /DEF=Homo sapiens hypothetical protein ASH1 (ASH1), mRNA. /FEA=mRNA /GEN=ASH1 /PROD=hypothetical protein ASH1 /DB_XREF=gi:8922080 /UG=Hs.102652 hypothetical protein ASH1 /FL=gb:AF257305.1 gb:NM_018489.1 NM_018489 ash1 (absent, small, or homeotic)-like (Drosophila) ASH1L 55870 NM_018489 /// XM_005245336 /// XM_005245337 /// XM_006711450 /// XM_006711451 /// XM_006711452 0006323 // DNA packaging // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218555_at NM_013366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013366.2 /DEF=Homo sapiens anaphase-promoting complex subunit 2 (APC2), mRNA. /FEA=mRNA /GEN=APC2 /PROD=anaphase-promoting complex 2 /DB_XREF=gi:7549800 /UG=Hs.23076 anaphase-promoting complex subunit 2 /FL=gb:AF191337.1 gb:NM_013366.2 NM_013366 anaphase promoting complex subunit 2 ANAPC2 29882 NM_013366 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008054 // cyclin catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031915 // positive regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 218556_at NM_014182 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014182.1 /DEF=Homo sapiens HSPC160 protein (HSPC160), mRNA. /FEA=mRNA /GEN=HSPC160 /PROD=HSPC160 protein /DB_XREF=gi:7661819 /UG=Hs.13144 HSPC160 protein /FL=gb:AF161509.1 gb:NM_014182.1 NM_014182 ORMDL sphingolipid biosynthesis regulator 2 ORMDL2 29095 NM_014182 0006672 // ceramide metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 218557_at NM_020202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020202.1 /DEF=Homo sapiens Nit protein 2 (NIT2), mRNA. /FEA=mRNA /GEN=NIT2 /PROD=Nit protein 2 /DB_XREF=gi:9910459 /UG=Hs.15627 Nit protein 2 /FL=gb:AF260334.1 gb:AF284574.1 gb:NM_020202.1 NM_020202 nitrilase family, member 2 NIT2 56954 NM_020202 0006107 // oxaloacetate metabolic process // inferred from direct assay /// 0006528 // asparagine metabolic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from direct assay /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0050152 // omega-amidase activity // inferred from direct assay 218558_s_at NM_017446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017446.1 /DEF=Homo sapiens hypothetical protein (PRED22), mRNA. /FEA=mRNA /GEN=PRED22 /PROD=hypothetical protein /DB_XREF=gi:8394038 /UG=Hs.167130 hypothetical protein /FL=gb:BC004896.1 gb:NM_017446.1 NM_017446 mitochondrial ribosomal protein L39 MRPL39 54148 NM_017446 /// NM_080794 /// XM_006724026 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218559_s_at NM_005461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005461.1 /DEF=Homo sapiens Kreisler (mouse) maf-related leucine zipper homolog (KRML), mRNA. /FEA=mRNA /GEN=KRML /PROD=Kreisler (mouse) maf-related leucine zipperhomolog /DB_XREF=gi:4885446 /UG=Hs.169487 Kreisler (mouse) maf-related leucine zipper homolog /FL=gb:AF134157.1 gb:NM_005461.1 NM_005461 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B MAFB 9935 NM_005461 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007379 // segment specification // inferred from electronic annotation /// 0007423 // sensory organ development // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0021571 // rhombomere 5 development // inferred from electronic annotation /// 0021572 // rhombomere 6 development // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035284 // brain segmentation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218560_s_at NM_023007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023007.1 /DEF=Homo sapiens hypothetical protein FLJ12517 (FLJ12517), mRNA. /FEA=mRNA /GEN=FLJ12517 /PROD=hypothetical protein FLJ12517 /DB_XREF=gi:12711669 /UG=Hs.184343 hypothetical protein FLJ12517 /FL=gb:NM_023007.1 NM_023007 jumonji domain containing 4 JMJD4 65094 NM_001161465 /// NM_023007 0005515 // protein binding // inferred from physical interaction 218561_s_at NM_020408 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020408.1 /DEF=Homo sapiens CGI-203 protein (CGI-203), mRNA. /FEA=mRNA /GEN=CGI-203 /PROD=CGI-203 protein /DB_XREF=gi:9966892 /UG=Hs.184860 CGI-203 protein /FL=gb:AF285118.1 gb:NM_020408.1 NM_020408 LYR motif containing 4 LYRM4 57128 NM_001164840 /// NM_001164841 /// NM_020408 /// NR_104417 /// NR_104418 /// XM_005249237 /// XM_005249239 /// XM_006715151 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 218562_s_at NM_018202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018202.1 /DEF=Homo sapiens hypothetical protein FLJ10747 (FLJ10747), mRNA. /FEA=mRNA /GEN=FLJ10747 /PROD=hypothetical protein FLJ10747 /DB_XREF=gi:8922637 /UG=Hs.189782 hypothetical protein FLJ10747 /FL=gb:NM_018202.1 NM_018202 transmembrane protein 57 TMEM57 55219 NM_001282564 /// NM_018202 /// XM_005245931 0007420 // brain development // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 218563_at NM_004542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004542.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD, B9) (NDUFA3), mRNA. /FEA=mRNA /GEN=NDUFA3 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 3 (9kD, B9) /DB_XREF=gi:4758771 /UG=Hs.198269 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD, B9) /FL=gb:AF044955.1 gb:AF070653.1 gb:NM_004542.1 NM_004542 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa NDUFA3 4696 NM_004542 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 218564_at BC002574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002574.1 /DEF=Homo sapiens, hypothetical protein FLJ10520, clone MGC:954, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10520 /DB_XREF=gi:12803494 /UG=Hs.209473 hypothetical protein FLJ10520 /FL=gb:BC002574.1 gb:NM_018124.1 BC002574 ring finger and WD repeat domain 3 RFWD3 55159 NM_018124 /// XM_005256021 /// XM_005256022 /// XM_006721227 /// XM_006721228 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097371 // MDM2/MDM4 family protein binding // inferred from physical interaction 218565_at BG223334 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG223334 /FEA=EST /DB_XREF=gi:12708855 /DB_XREF=est:naf79d11.x1 /CLONE=IMAGE:4170285 /UG=Hs.224137 hypothetical protein /FL=gb:AF161459.1 gb:NM_016390.1 BG223334 chromosome 9 open reading frame 114 C9orf114 51490 NM_016390 /// XM_005252045 /// XM_005252046 0044822 // poly(A) RNA binding // inferred from direct assay 218566_s_at NM_012124 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012124.1 /DEF=Homo sapiens chord domain-containing protein 1 (CHP1), mRNA. /FEA=mRNA /GEN=CHP1 /PROD=chord domain-containing protein 1 /DB_XREF=gi:6912303 /UG=Hs.22857 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 /FL=gb:AF192466.1 gb:NM_012124.1 NM_012124 cysteine and histidine-rich domain (CHORD) containing 1 CHORDC1 26973 NM_001144073 /// NM_012124 /// XR_247194 /// XR_247195 0006950 // response to stress // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity /// 0080134 // regulation of response to stress // inferred from electronic annotation /// 1900034 // regulation of cellular response to heat // inferred from sequence or structural similarity /// 2000299 // negative regulation of Rho-dependent protein serine/threonine kinase activity // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from physical interaction 218567_x_at NM_005700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005700.1 /DEF=Homo sapiens dipeptidylpeptidase III (DPP3), mRNA. /FEA=mRNA /GEN=DPP3 /PROD=dipeptidylpeptidase III /DB_XREF=gi:11342681 /UG=Hs.22880 dipeptidylpeptidase III /FL=gb:NM_005700.1 gb:BC001446.1 NM_005700 dipeptidyl-peptidase 3 DPP3 10072 NM_001256670 /// NM_005700 /// NM_130443 0006508 // proteolysis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218568_at NM_018238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018238.1 /DEF=Homo sapiens hypothetical protein FLJ10842 (FLJ10842), mRNA. /FEA=mRNA /GEN=FLJ10842 /PROD=hypothetical protein FLJ10842 /DB_XREF=gi:8922700 /UG=Hs.260238 hypothetical protein FLJ10842 /FL=gb:NM_018238.1 NM_018238 acylglycerol kinase AGK 55750 NM_018238 /// XM_005250021 /// XM_005250023 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation /// 0046834 // lipid phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001727 // lipid kinase activity // inferred from electronic annotation /// 0001729 // ceramide kinase activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047620 // acylglycerol kinase activity // inferred from electronic annotation 218569_s_at NM_018095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018095.1 /DEF=Homo sapiens hypothetical protein FLJ10450 (FLJ10450), mRNA. /FEA=mRNA /GEN=FLJ10450 /PROD=hypothetical protein FLJ10450 /DB_XREF=gi:8922425 /UG=Hs.267604 hypothetical protein FLJ10450 /FL=gb:BC002736.1 gb:NM_018095.1 NM_018095 kelch repeat and BTB (POZ) domain containing 4 KBTBD4 55709 NM_016506 /// NM_018095 /// NR_024222 /// XM_006718261 /// XM_006718262 0006470 // protein dephosphorylation // not recorded /// 0006470 // protein dephosphorylation // /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // not recorded /// 0046855 // inositol phosphate dephosphorylation // 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005739 // mitochondrion // /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // not recorded /// 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008962 // phosphatidylglycerophosphatase activity // inferred from sequence or structural similarity /// 0008962 // phosphatidylglycerophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 218570_at NM_018095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018095.1 /DEF=Homo sapiens hypothetical protein FLJ10450 (FLJ10450), mRNA. /FEA=mRNA /GEN=FLJ10450 /PROD=hypothetical protein FLJ10450 /DB_XREF=gi:8922425 /UG=Hs.267604 hypothetical protein FLJ10450 /FL=gb:BC002736.1 gb:NM_018095.1 NM_018095 kelch repeat and BTB (POZ) domain containing 4 /// protein tyrosine phosphatase, mitochondrial 1 KBTBD4 /// PTPMT1 55709 /// 114971 NM_001143984 /// NM_016506 /// NM_018095 /// NM_175732 /// NR_024222 /// XM_006718261 /// XM_006718262 0006470 // protein dephosphorylation // not recorded /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046855 // inositol phosphate dephosphorylation // not recorded 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008962 // phosphatidylglycerophosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 218571_s_at NM_014169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014169.1 /DEF=Homo sapiens HSPC134 protein (HSPC134), mRNA. /FEA=mRNA /GEN=HSPC134 /PROD=HSPC134 protein /DB_XREF=gi:7661793 /UG=Hs.279761 HSPC134 protein /FL=gb:AF212243.1 gb:AF161483.1 gb:NM_014169.1 NM_014169 charged multivesicular body protein 4A /// transmembrane 9 superfamily member 1 CHMP4A /// TM9SF1 10548 /// 29082 NM_001014842 /// NM_001289006 /// NM_006405 /// NM_014169 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006900 // membrane budding // inferred from genetic interaction /// 0006900 // membrane budding // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0051260 // protein homooligomerization // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0097320 // membrane tubulation // inferred from genetic interaction /// 0097320 // membrane tubulation // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from mutant phenotype /// 1902902 // negative regulation of autophagic vacuole assembly // inferred from mutant phenotype 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0000815 // ESCRT III complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 218572_at NM_014169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014169.1 /DEF=Homo sapiens HSPC134 protein (HSPC134), mRNA. /FEA=mRNA /GEN=HSPC134 /PROD=HSPC134 protein /DB_XREF=gi:7661793 /UG=Hs.279761 HSPC134 protein /FL=gb:AF212243.1 gb:AF161483.1 gb:NM_014169.1 NM_014169 charged multivesicular body protein 4A /// transmembrane 9 superfamily member 1 CHMP4A /// TM9SF1 10548 /// 29082 NM_001014842 /// NM_001289006 /// NM_006405 /// NM_014169 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006900 // membrane budding // inferred from genetic interaction /// 0006900 // membrane budding // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0051260 // protein homooligomerization // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0097320 // membrane tubulation // inferred from genetic interaction /// 0097320 // membrane tubulation // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from mutant phenotype /// 1902902 // negative regulation of autophagic vacuole assembly // inferred from mutant phenotype 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0000815 // ESCRT III complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 218573_at NM_014061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014061.1 /DEF=Homo sapiens APR-1 protein (APR-1), mRNA. /FEA=mRNA /GEN=APR-1 /PROD=APR-1 protein /DB_XREF=gi:7661529 /UG=Hs.279819 APR-1 protein /FL=gb:AF320912.1 gb:AF143235.3 gb:NM_014061.1 NM_014061 melanoma antigen family H, 1 MAGEH1 28986 NM_014061 0006915 // apoptotic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 218574_s_at NM_014583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014583.1 /DEF=Homo sapiens LIM and cysteine-rich domains 1 (LMCD1), mRNA. /FEA=mRNA /GEN=LMCD1 /PROD=LIM and cysteine-rich domains 1 /DB_XREF=gi:7657308 /UG=Hs.279943 LIM and cysteine-rich domains 1 /FL=gb:AF216709.1 gb:BC000646.1 gb:AF169284.1 gb:NM_014583.1 NM_014583 LIM and cysteine-rich domains 1 LMCD1 29995 NM_001278233 /// NM_001278234 /// NM_001278235 /// NM_014583 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from mutant phenotype /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218575_at NM_022662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022662.1 /DEF=Homo sapiens meiotic checkpoint regulator (MCPR), mRNA. /FEA=mRNA /GEN=MCPR /PROD=meiotic checkpoint regulator /DB_XREF=gi:12056970 /UG=Hs.40137 anaphase-promoting complex 1; meiotic checkpoint regulator /FL=gb:NM_022662.1 NM_022662 anaphase promoting complex subunit 1 /// anaphase-promoting complex subunit 1-like ANAPC1 /// LOC730268 64682 /// 730268 NM_022662 /// XM_005264679 /// XM_005276206 /// XM_006712690 /// XM_006712691 /// XM_006726384 /// XR_426509 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation 218576_s_at NM_007240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007240.1 /DEF=Homo sapiens dual specificity phosphatase 12 (DUSP12), mRNA. /FEA=mRNA /GEN=DUSP12 /PROD=dual specificity phosphatase 12 /DB_XREF=gi:6005955 /UG=Hs.44229 dual specificity phosphatase 12 /FL=gb:AF119226.1 gb:NM_007240.1 NM_007240 dual specificity phosphatase 12 DUSP12 11266 NM_007240 /// XM_005244862 0006464 // cellular protein modification process // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // not recorded /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218577_at NM_017768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017768.1 /DEF=Homo sapiens hypothetical protein FLJ20331 (FLJ20331), mRNA. /FEA=mRNA /GEN=FLJ20331 /PROD=hypothetical protein FLJ20331 /DB_XREF=gi:8923306 /UG=Hs.50848 hypothetical protein FLJ20331 /FL=gb:BC003407.1 gb:NM_017768.1 NM_017768 leucine rich repeat containing 40 LRRC40 55631 NM_017768 /// XM_005271013 /// XM_006710757 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218578_at NM_024529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024529.1 /DEF=Homo sapiens hypothetical protein FLJ23316 (FLJ23316), mRNA. /FEA=mRNA /GEN=FLJ23316 /PROD=hypothetical protein FLJ23316 /DB_XREF=gi:13375677 /UG=Hs.5722 hypothetical protein FLJ23316 /FL=gb:AF312865.1 gb:NM_024529.1 NM_024529 cell division cycle 73 CDC73 79577 NM_024529 /// XM_006711537 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from mutant phenotype /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218579_s_at NM_021931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021931.1 /DEF=Homo sapiens hypothetical protein FLJ22759 (FLJ22759), mRNA. /FEA=mRNA /GEN=FLJ22759 /PROD=hypothetical protein FLJ22759 /DB_XREF=gi:11345467 /UG=Hs.7174 hypothetical protein FLJ22759 /FL=gb:NM_021931.1 NM_021931 DEAH (Asp-Glu-Ala-His) box polypeptide 35 DHX35 60625 NM_001190809 /// NM_021931 /// NR_033905 /// XM_006723848 /// XR_430306 /// XR_430307 /// XR_430308 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218580_x_at NM_017900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017900.1 /DEF=Homo sapiens hypothetical protein FLJ20608 (FLJ20608), mRNA. /FEA=mRNA /GEN=FLJ20608 /PROD=hypothetical protein FLJ20608 /DB_XREF=gi:8923564 /UG=Hs.76239 hypothetical protein FLJ20608 /FL=gb:NM_017900.1 NM_017900 aurora kinase A interacting protein 1 AURKAIP1 54998 NM_001127229 /// NM_001127230 /// NM_017900 0045839 // negative regulation of mitosis // non-traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218581_at NM_022060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022060.1 /DEF=Homo sapiens hypothetical protein FLJ12816 (FLJ12816), mRNA. /FEA=mRNA /GEN=FLJ12816 /PROD=hypothetical protein FLJ12816 /DB_XREF=gi:11545766 /UG=Hs.9175 hypothetical protein FLJ12816 /FL=gb:NM_022060.1 NM_022060 abhydrolase domain containing 4 ABHD4 63874 NM_022060 /// XM_005267986 /// XR_245712 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 218582_at NM_017824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017824.1 /DEF=Homo sapiens hypothetical protein FLJ20445 (FLJ20445), mRNA. /FEA=mRNA /GEN=FLJ20445 /PROD=hypothetical protein FLJ20445 /DB_XREF=gi:8923414 /UG=Hs.10340 hypothetical protein FLJ20445 /FL=gb:NM_017824.1 NM_017824 membrane-associated ring finger (C3HC4) 5 MARCH5 54708 NM_017824 /// XM_005269923 0000209 // protein polyubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype /// 0090140 // regulation of mitochondrial fission // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from mutant phenotype /// 0090344 // negative regulation of cell aging // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from physical interaction 218583_s_at NM_020640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020640.1 /DEF=Homo sapiens RP42 homolog (RP42), mRNA. /FEA=mRNA /GEN=RP42 /PROD=RP42 homolog /DB_XREF=gi:10190677 /UG=Hs.104613 RP42 homolog /FL=gb:NM_020640.1 gb:AF292100.2 NM_020640 DCN1, defective in cullin neddylation 1, domain containing 1 DCUN1D1 54165 NM_020640 /// XM_005247539 /// XM_005247540 0000151 // ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218584_at NM_024549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024549.1 /DEF=Homo sapiens hypothetical protein FLJ21127 (FLJ21127), mRNA. /FEA=mRNA /GEN=FLJ21127 /PROD=hypothetical protein FLJ21127 /DB_XREF=gi:13375712 /UG=Hs.11500 hypothetical protein FLJ21127 /FL=gb:NM_024549.1 NM_024549 tectonic family member 1 TCTN1 79600 NM_001082537 /// NM_001082538 /// NM_001173975 /// NM_001173976 /// NM_024549 /// XM_005253934 /// XM_005253935 /// XM_005253936 /// XM_006719594 /// XM_006719595 /// XM_006719596 /// XM_006719597 /// XM_006719598 /// XM_006719599 /// XM_006719600 /// XR_243021 /// XR_243022 /// XR_429116 /// XR_429117 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0021523 // somatic motor neuron differentiation // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021956 // central nervous system interneuron axonogenesis // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from electronic annotation /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218585_s_at NM_016448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016448.1 /DEF=Homo sapiens L2DTL protein (L2DTL), mRNA. /FEA=mRNA /GEN=L2DTL /PROD=L2DTL protein /DB_XREF=gi:7705575 /UG=Hs.126774 L2DTL protein /FL=gb:AF195765.1 gb:NM_016448.1 NM_016448 denticleless E3 ubiquitin protein ligase homolog (Drosophila) DTL 51514 NM_001286229 /// NM_001286230 /// NM_016448 0000209 // protein polyubiquitination // inferred from direct assay /// 0000209 // protein polyubiquitination // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019985 // translesion synthesis // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218586_at NM_018270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018270.1 /DEF=Homo sapiens hypothetical protein FLJ10914 (FLJ10914), mRNA. /FEA=mRNA /GEN=FLJ10914 /PROD=hypothetical protein FLJ10914 /DB_XREF=gi:8922763 /UG=Hs.143954 hypothetical protein FLJ10914 /FL=gb:NM_018270.1 NM_018270 MRG/MORF4L binding protein MRGBP 55257 NM_018270 /// XR_244123 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0043189 // H4/H2A histone acetyltransferase complex // inferred from electronic annotation 218587_s_at NM_020231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020231.1 /DEF=Homo sapiens x 010 protein (MDS010), mRNA. /FEA=mRNA /GEN=MDS010 /PROD=x 010 protein /DB_XREF=gi:9910427 /UG=Hs.159397 x 010 protein /FL=gb:AF168711.1 gb:NM_020231.1 NM_020231 protein O-glucosyltransferase 1 POGLUT1 56983 NM_152305 /// NR_024265 /// XM_006713704 /// XM_006713705 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0008593 // regulation of Notch signaling pathway // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030158 // protein xylosyltransferase activity // inferred from electronic annotation /// 0035251 // UDP-glucosyltransferase activity // inferred from direct assay /// 0035252 // UDP-xylosyltransferase activity // inferred from electronic annotation /// 0046527 // glucosyltransferase activity // inferred from direct assay 218588_s_at NM_018691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018691.1 /DEF=Homo sapiens chromosome 5 open reading frame 3 (C5ORF3), mRNA. /FEA=mRNA /GEN=C5ORF3 /PROD=hypothetical protein /DB_XREF=gi:8922068 /UG=Hs.166551 chromosome 5 open reading frame 3 /FL=gb:NM_018691.1 NM_018691 family with sequence similarity 114, member A2 FAM114A2 10827 NM_018691 /// XM_005268359 /// XM_005268360 /// XM_005268361 0017076 // purine nucleotide binding // non-traceable author statement 218589_at NM_005767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005767.1 /DEF=Homo sapiens purinergic receptor (family A group 5) (P2Y5), mRNA. /FEA=mRNA /GEN=P2Y5 /PROD=purinergic receptor (family A group 5) /DB_XREF=gi:5031968 /UG=Hs.189999 purinergic receptor (family A group 5) /FL=gb:AF000546.1 gb:NM_005767.1 NM_005767 lysophosphatidic acid receptor 6 LPAR6 10161 NM_001162497 /// NM_001162498 /// NM_005767 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 218590_at NM_021830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021830.1 /DEF=Homo sapiens hypothetical protein FLJ21832 (FLJ21832), mRNA. /FEA=mRNA /GEN=FLJ21832 /PROD=hypothetical protein FLJ21832 /DB_XREF=gi:11141908 /UG=Hs.22678 hypothetical protein FLJ21832 /FL=gb:NM_021830.1 NM_021830 chromosome 10 open reading frame 2 C10orf2 56652 NM_001163812 /// NM_001163813 /// NM_001163814 /// NM_021830 /// XM_006717921 /// XM_006717922 /// XR_246100 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from mutant phenotype /// 0006264 // mitochondrial DNA replication // non-traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0034214 // protein hexamerization // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043139 // 5'-3' DNA helicase activity // inferred from direct assay 218591_s_at NM_024894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024894.1 /DEF=Homo sapiens hypothetical protein FLJ14075 (FLJ14075), mRNA. /FEA=mRNA /GEN=FLJ14075 /PROD=hypothetical protein FLJ14075 /DB_XREF=gi:13430871 /UG=Hs.235498 hypothetical protein FLJ14075 /FL=gb:NM_024894.1 NM_024894 nucleolar protein 10 NOL10 79954 NM_001261392 /// NM_001261394 /// NM_024894 /// NR_048552 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218592_s_at NM_017829 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017829.1 /DEF=Homo sapiens hypothetical protein FLJ20454 (FLJ20454), mRNA. /FEA=mRNA /GEN=FLJ20454 /PROD=hypothetical protein FLJ20454 /DB_XREF=gi:8923424 /UG=Hs.26890 hypothetical protein FLJ20454 /FL=gb:AF273271.1 gb:NM_017829.1 NM_017829 cat eye syndrome chromosome region, candidate 5 CECR5 27440 NM_017829 /// NM_033070 /// XM_005261236 /// XM_005261237 0005739 // mitochondrion // inferred from electronic annotation 218593_at NM_018077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018077.1 /DEF=Homo sapiens hypothetical protein FLJ10377 (FLJ10377), mRNA. /FEA=mRNA /GEN=FLJ10377 /PROD=hypothetical protein FLJ10377 /DB_XREF=gi:8922387 /UG=Hs.274263 hypothetical protein FLJ10377 /FL=gb:NM_018077.1 NM_018077 RNA binding motif protein 28 RBM28 55131 NM_001166135 /// NM_018077 /// XM_006716042 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218594_at NM_018072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018072.1 /DEF=Homo sapiens hypothetical protein FLJ10359 (FLJ10359), mRNA. /FEA=mRNA /GEN=FLJ10359 /PROD=hypothetical protein FLJ10359 /DB_XREF=gi:8922377 /UG=Hs.285861 hypothetical protein FLJ10359 /FL=gb:NM_018072.1 NM_018072 HEAT repeat containing 1 HEATR1 55127 NM_018072 /// XR_426917 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218595_s_at NM_018072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018072.1 /DEF=Homo sapiens hypothetical protein FLJ10359 (FLJ10359), mRNA. /FEA=mRNA /GEN=FLJ10359 /PROD=hypothetical protein FLJ10359 /DB_XREF=gi:8922377 /UG=Hs.285861 hypothetical protein FLJ10359 /FL=gb:NM_018072.1 NM_018072 HEAT repeat containing 1 HEATR1 55127 NM_018072 /// XR_426917 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218596_at NM_018201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018201.1 /DEF=Homo sapiens hypothetical protein FLJ10743 (FLJ10743), mRNA. /FEA=mRNA /GEN=FLJ10743 /PROD=hypothetical protein FLJ10743 /DB_XREF=gi:8922634 /UG=Hs.3376 hypothetical protein FLJ10743 /FL=gb:NM_018201.1 NM_018201 TBC1 domain family, member 13 TBC1D13 54662 NM_001286772 /// NM_018201 /// XM_005252060 /// XM_006717147 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218597_s_at NM_018464 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018464.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS029 (MDS029), mRNA. /FEA=mRNA /GEN=MDS029 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS029 /DB_XREF=gi:8923929 /UG=Hs.43549 uncharacterized hematopoietic stemprogenitor cells protein MDS029 /FL=gb:AF220049.1 gb:NM_018464.1 NM_018464 CDGSH iron sulfur domain 1 CISD1 55847 NM_018464 /// XM_006717916 0043457 // regulation of cellular respiration // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 218598_at NM_021930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021930.1 /DEF=Homo sapiens hypothetical protein FLJ11785 (FLJ11785), mRNA. /FEA=mRNA /GEN=FLJ11785 /PROD=hypothetical protein FLJ11785 /DB_XREF=gi:11345465 /UG=Hs.44625 Rad50-interacting protein 1 /FL=gb:NM_021930.1 gb:AF317622.1 NM_021930 RAD50 interactor 1 RINT1 60561 NM_021930 /// XM_005250524 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218599_at NM_005132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005132.1 /DEF=Homo sapiens Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family (REC8), mRNA. /FEA=mRNA /GEN=REC8 /PROD=Rec8p, a meiotic recombination and sisterchromatid cohesion phosphoprotein of the rad21p family /DB_XREF=gi:9845292 /UG=Hs.4767 Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family /FL=gb:BC004159.1 gb:NM_005132.1 NM_005132 REC8 meiotic recombination protein REC8 9985 NM_001048205 /// NM_005132 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // traceable author statement /// 0007126 // meiotic nuclear division // traceable author statement /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030999 // linear element assembly // inferred from electronic annotation /// 0072520 // seminiferous tubule development // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from electronic annotation /// 0000778 // condensed nuclear chromosome kinetochore // inferred from electronic annotation /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0030893 // meiotic cohesin complex // inferred from electronic annotation /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation 218600_at NM_030576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030576.1 /DEF=Homo sapiens hypothetical protein MGC10986 (MGC10986), mRNA. /FEA=mRNA /GEN=MGC10986 /PROD=hypothetical protein MGC10986 /DB_XREF=gi:13386489 /UG=Hs.50601 hypothetical protein MGC10986 /FL=gb:BC004400.1 gb:NM_030576.1 NM_030576 LIM domain containing 2 LIMD2 80774 NM_030576 /// XM_005257703 /// XM_005257704 /// XM_005257705 /// XM_006722124 /// XM_006722125 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218601_at NM_017920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017920.1 /DEF=Homo sapiens hypothetical protein FLJ20654 (FLJ20654), mRNA. /FEA=mRNA /GEN=FLJ20654 /PROD=hypothetical protein FLJ20654 /DB_XREF=gi:8923605 /UG=Hs.5131 hypothetical protein FLJ20654 /FL=gb:NM_017920.1 NM_017920 upregulator of cell proliferation URGCP 55665 NM_001077663 /// NM_001077664 /// NM_001290075 /// NM_001290076 /// NM_017920 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005525 // GTP binding // inferred from electronic annotation 218602_s_at NM_017645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017645.1 /DEF=Homo sapiens hypothetical protein FLJ20060 (FLJ20060), mRNA. /FEA=mRNA /GEN=FLJ20060 /PROD=hypothetical protein FLJ20060 /DB_XREF=gi:8923062 /UG=Hs.54617 hypothetical protein FLJ20060 /FL=gb:NM_017645.1 NM_017645 HAUS augmin-like complex, subunit 6 HAUS6 54801 NM_001270890 /// NM_017645 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 218603_at NM_016217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016217.1 /DEF=Homo sapiens hHDC for homolog of Drosophila headcase (LOC51696), mRNA. /FEA=mRNA /GEN=LOC51696 /PROD=hHDC for homolog of Drosophila headcase /DB_XREF=gi:7706434 /UG=Hs.6679 hHDC for homolog of Drosophila headcase /FL=gb:AB033492.1 gb:NM_016217.1 NM_016217 headcase homolog (Drosophila) HECA 51696 NM_016217 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030323 // respiratory tube development // non-traceable author statement 0016020 // membrane // inferred from direct assay 218604_at NM_014319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014319.2 /DEF=Homo sapiens integral inner nuclear membrane protein (MAN1), mRNA. /FEA=mRNA /GEN=MAN1 /PROD=integral inner nuclear membrane protein /DB_XREF=gi:7706606 /UG=Hs.7256 integral inner nuclear membrane protein /FL=gb:AF112299.2 gb:NM_014319.2 NM_014319 LEM domain containing 3 LEMD3 23592 NM_001167614 /// NM_014319 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005639 // integral component of nuclear inner membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218605_at NM_022366 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022366.1 /DEF=Homo sapiens hypothetical protein FLJ23182 (FLJ23182), mRNA. /FEA=mRNA /GEN=FLJ23182 /PROD=hypothetical protein FLJ23182 /DB_XREF=gi:11641288 /UG=Hs.7395 hypothetical protein FLJ23182 /FL=gb:NM_022366.1 gb:BC003383.1 NM_022366 transcription factor B2, mitochondrial TFB2M 64216 NM_022366 0000154 // rRNA modification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218606_at NM_017740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017740.1 /DEF=Homo sapiens hypothetical protein FLJ20279 (FLJ20279), mRNA. /FEA=mRNA /GEN=FLJ20279 /PROD=hypothetical protein FLJ20279 /DB_XREF=gi:8923254 /UG=Hs.9725 hypothetical protein FLJ20279 /FL=gb:NM_017740.1 NM_017740 zinc finger, DHHC-type containing 7 ZDHHC7 55625 NM_001145548 /// NM_017740 /// XR_429724 0018230 // peptidyl-L-cysteine S-palmitoylation // inferred from mutant phenotype /// 0018345 // protein palmitoylation // inferred from direct assay 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218607_s_at NM_018115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018115.1 /DEF=Homo sapiens hypothetical protein FLJ10498 (FLJ10498), mRNA. /FEA=mRNA /GEN=FLJ10498 /PROD=hypothetical protein FLJ10498 /DB_XREF=gi:8922466 /UG=Hs.109045 hypothetical protein FLJ10498 /FL=gb:NM_018115.1 NM_018115 SDA1 domain containing 1 SDAD1 55153 NM_001288983 /// NM_001288984 /// NM_018115 /// XM_005263102 /// XM_005263105 0000055 // ribosomal large subunit export from nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042273 // ribosomal large subunit biogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005488 // binding // inferred from electronic annotation 218608_at NM_022089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022089.1 /DEF=Homo sapiens putative ATPase (HSA9947), mRNA. /FEA=mRNA /GEN=HSA9947 /PROD=putative ATPase /DB_XREF=gi:13435128 /UG=Hs.128866 putative ATPase /FL=gb:NM_022089.1 NM_022089 ATPase type 13A2 ATP13A2 23400 NM_001141973 /// NM_001141974 /// NM_022089 /// XM_005245809 /// XM_005245810 /// XM_005245811 /// XM_005245812 /// XM_005245813 /// XM_005245815 /// XM_006710512 /// XM_006710513 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218609_s_at NM_001161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001161.1 /DEF=Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 2 (NUDT2), mRNA. /FEA=mRNA /GEN=NUDT2 /PROD=nudix (nucleoside diphosphate linked moietyX)-type motif 2 /DB_XREF=gi:4502124 /UG=Hs.14142 nudix (nucleoside diphosphate linked moiety X)-type motif 2 /FL=gb:BC004926.1 gb:NM_001161.1 NM_001161 nudix (nucleoside diphosphate linked moiety X)-type motif 2 NUDT2 318 NM_001161 /// NM_001244390 /// NM_147172 /// NM_147173 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004081 // bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation /// 0008796 // bis(5'-nucleosyl)-tetraphosphatase activity // inferred from electronic annotation /// 0008803 // bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 218610_s_at NM_018340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018340.1 /DEF=Homo sapiens hypothetical protein FLJ11151 (FLJ11151), mRNA. /FEA=mRNA /GEN=FLJ11151 /PROD=hypothetical protein FLJ11151 /DB_XREF=gi:8922900 /UG=Hs.14992 hypothetical protein FLJ11151 /FL=gb:NM_018340.1 NM_018340 calcineurin-like phosphoesterase domain containing 1 CPPED1 55313 NM_001099455 /// NM_018340 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218611_at NM_016545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016545.1 /DEF=Homo sapiens hypothetical protein SBBI48 (LOC51278), mRNA. /FEA=mRNA /GEN=LOC51278 /PROD=hypothetical protein SBBI48 /DB_XREF=gi:7706080 /UG=Hs.15725 hypothetical protein SBBI48 /FL=gb:BC000128.2 gb:AF178984.1 gb:NM_016545.1 NM_016545 immediate early response 5 IER5 51278 NM_016545 218612_s_at NM_005706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005706.1 /DEF=Homo sapiens tumor suppressing subtransferable candidate 4 (TSSC4), mRNA. /FEA=mRNA /GEN=TSSC4 /PROD=tumor suppressing subtransferable candidate 4 /DB_XREF=gi:5032204 /UG=Hs.165743 tumor suppressing subtransferable candidate 4 /FL=gb:AF125568.1 gb:NM_005706.1 NM_005706 tumor suppressing subtransferable candidate 4 TSSC4 10078 NM_005706 /// XM_005252722 /// XM_005252724 /// XM_006718118 218613_at NM_018422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018422.1 /DEF=Homo sapiens hypothetical protein DKFZp761K1423 (DKFZp761K1423), mRNA. /FEA=mRNA /GEN=DKFZp761K1423 /PROD=hypothetical protein DKFZp761K1423 /DB_XREF=gi:8922171 /UG=Hs.236438 hypothetical protein DKFZp761K1423 /FL=gb:NM_018422.1 NM_018422 pleckstrin and Sec7 domain containing 3 PSD3 23362 NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation 218614_at NM_018169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018169.1 /DEF=Homo sapiens hypothetical protein FLJ10652 (FLJ10652), mRNA. /FEA=mRNA /GEN=FLJ10652 /PROD=hypothetical protein FLJ10652 /DB_XREF=gi:8922572 /UG=Hs.236844 hypothetical protein FLJ10652 /FL=gb:NM_018169.1 NM_018169 KIAA1551 KIAA1551 55196 NM_018169 /// XM_005253405 /// XM_006719099 218615_s_at NM_018266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018266.1 /DEF=Homo sapiens hypothetical protein FLJ10902 (FLJ10902), mRNA. /FEA=mRNA /GEN=FLJ10902 /PROD=hypothetical protein FLJ10902 /DB_XREF=gi:8922755 /UG=Hs.247112 hypothetical protein FLJ10902 /FL=gb:NM_018266.1 NM_018266 transmembrane protein 39A TMEM39A 55254 NM_018266 /// NR_073506 /// XM_005247577 /// XM_005247578 /// XM_006713687 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218616_at NM_020395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020395.1 /DEF=Homo sapiens hypothetical nuclear factor SBBI22 (LOC57117), mRNA. /FEA=mRNA /GEN=LOC57117 /PROD=hypothetical nuclear factor SBBI22 /DB_XREF=gi:9966872 /UG=Hs.26323 hypothetical nuclear factor SBBI22 /FL=gb:AF242524.1 gb:NM_020395.1 NM_020395 integrator complex subunit 12 INTS12 57117 NM_001142471 /// NM_020395 /// XM_005263148 /// XM_005263149 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218617_at NM_017646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017646.1 /DEF=Homo sapiens tRNA isopentenylpyrophosphate transferase (IPT), mRNA. /FEA=mRNA /GEN=IPT /PROD=tRNA isopentenylpyrophosphate transferase /DB_XREF=gi:8923064 /UG=Hs.288036 tRNA isopentenylpyrophosphate transferase /FL=gb:NM_017646.1 NM_017646 tRNA isopentenyltransferase 1 TRIT1 54802 NM_017646 /// XM_005270954 /// XM_006710706 /// XR_246278 0008033 // tRNA processing // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052381 // tRNA dimethylallyltransferase activity // traceable author statement 218618_s_at NM_022763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022763.1 /DEF=Homo sapiens hypothetical protein FLJ23399 (FLJ23399), mRNA. /FEA=mRNA /GEN=FLJ23399 /PROD=hypothetical protein FLJ23399 /DB_XREF=gi:12232434 /UG=Hs.299883 hypothetical protein FLJ23399 /FL=gb:NM_022763.1 NM_022763 fibronectin type III domain containing 3B /// uncharacterized LOC101928615 FNDC3B /// LOC101928615 64778 /// 101928615 NM_001135095 /// NM_022763 /// XR_241616 /// XR_249499 /// XR_251497 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218619_s_at NM_003173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003173.1 /DEF=Homo sapiens suppressor of variegation 3-9 (Drosophila) homolog 1 (SUV39H1), mRNA. /FEA=mRNA /GEN=SUV39H1 /PROD=suppressor of variegation 3-9 (Drosophila)homolog /DB_XREF=gi:4507320 /UG=Hs.37936 suppressor of variegation 3-9 (Drosophila) homolog 1 /FL=gb:AF019968.1 gb:NM_003173.1 NM_003173 suppressor of variegation 3-9 homolog 1 (Drosophila) SUV39H1 6839 NM_001282166 /// NM_003173 0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0036123 // histone H3-K9 dimethylation // inferred from sequence or structural similarity /// 0036124 // histone H3-K9 trimethylation // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from direct assay /// 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005652 // nuclear lamina // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0033553 // rDNA heterochromatin // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 218620_s_at AF131220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF131220.1 /DEF=Homo sapiens HEMK homolog (HEMK) mRNA, complete cds. /FEA=mRNA /GEN=HEMK /PROD=HEMK homolog /DB_XREF=gi:4589247 /UG=Hs.46907 HEMK homolog 7kb /FL=gb:BC000781.1 gb:AF131220.1 gb:AF172244.1 gb:NM_016173.1 AF131220 HemK methyltransferase family member 1 HEMK1 51409 NM_016173 /// XM_005265218 /// XM_005265219 0006306 // DNA methylation // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218621_at NM_016173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016173.1 /DEF=Homo sapiens HEMK homolog 7kb (HEMK), mRNA. /FEA=mRNA /GEN=HEMK /PROD=HEMK homolog 7kb /DB_XREF=gi:7705408 /UG=Hs.46907 HEMK homolog 7kb /FL=gb:BC000781.1 gb:AF131220.1 gb:AF172244.1 gb:NM_016173.1 NM_016173 HemK methyltransferase family member 1 HEMK1 51409 NM_016173 /// XM_005265218 /// XM_005265219 0006306 // DNA methylation // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218622_at NM_024057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024057.1 /DEF=Homo sapiens hypothetical protein MGC5585 (MGC5585), mRNA. /FEA=mRNA /GEN=MGC5585 /PROD=hypothetical protein MGC5585 /DB_XREF=gi:13129027 /UG=Hs.5152 hypothetical protein MGC5585 /FL=gb:BC000861.1 gb:NM_024057.1 NM_024057 nucleoporin 37kDa NUP37 79023 NM_024057 /// XM_005269144 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 218623_at NM_015980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015980.1 /DEF=Homo sapiens HMP19 protein (LOC51617), mRNA. /FEA=mRNA /GEN=LOC51617 /PROD=HMP19 protein /DB_XREF=gi:7706283 /UG=Hs.70669 HMP19 protein /FL=gb:BC002619.1 gb:AF133422.1 gb:AF113537.1 gb:NM_015980.1 NM_015980 HMP19 protein HMP19 51617 NM_015980 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from electronic annotation 0032051 // clathrin light chain binding // inferred from electronic annotation 218624_s_at NM_023939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023939.1 /DEF=Homo sapiens hypothetical protein MGC2752 (MGC2752), mRNA. /FEA=mRNA /GEN=MGC2752 /PROD=hypothetical protein MGC2752 /DB_XREF=gi:13027609 /UG=Hs.7845 hypothetical protein MGC2752 /FL=gb:BC000766.1 gb:BC001952.1 gb:NM_023939.1 NM_023939 CENPBD1 pseudogene 1 CENPBD1P1 65996 NM_023939 /// NR_026052 218625_at NM_016588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016588.1 /DEF=Homo sapiens neuritin (LOC51299), mRNA. /FEA=mRNA /GEN=LOC51299 /PROD=neuritin /DB_XREF=gi:7706122 /UG=Hs.103291 neuritin /FL=gb:BC002683.1 gb:AF136631.1 gb:NM_016588.1 NM_016588 neuritin 1 NRN1 51299 NM_001278710 /// NM_001278711 /// NM_016588 /// XM_006715106 /// XM_006715107 0007399 // nervous system development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 218626_at NM_019843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019843.2 /DEF=Homo sapiens eIF4E-transporter (4E-T), mRNA. /FEA=mRNA /GEN=4E-T /PROD=eIF4E-transporter /DB_XREF=gi:10947034 /UG=Hs.12720 eIF4E-transporter /FL=gb:NM_019843.2 gb:AF240775.1 NM_019843 eukaryotic translation initiation factor 4E nuclear import factor 1 EIF4ENIF1 56478 NM_001164501 /// NM_001164502 /// NM_019843 /// XM_005261686 /// XM_005261687 /// XM_005261688 /// XM_006724281 /// XM_006724282 /// XM_006724283 /// XM_006724284 0006413 // translational initiation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 218627_at NM_018370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018370.1 /DEF=Homo sapiens hypothetical protein FLJ11259 (FLJ11259), mRNA. /FEA=mRNA /GEN=FLJ11259 /PROD=hypothetical protein FLJ11259 /DB_XREF=gi:8922957 /UG=Hs.184465 hypothetical protein FLJ11259 /FL=gb:NM_018370.1 NM_018370 DNA-damage regulated autophagy modulator 1 DRAM1 55332 NM_018370 /// XM_005269004 /// XM_005269005 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred by curator 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218628_at NM_016053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016053.1 /DEF=Homo sapiens CGI-116 protein (LOC51019), mRNA. /FEA=mRNA /GEN=LOC51019 /PROD=CGI-116 protein /DB_XREF=gi:7705621 /UG=Hs.18885 CGI-116 protein /FL=gb:AF151874.1 gb:NM_016053.1 NM_016053 coiled-coil domain containing 53 CCDC53 51019 NM_016053 /// XM_005268939 /// XM_005268940 0015629 // actin cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218629_at NM_005631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005631.1 /DEF=Homo sapiens smoothened (Drosophila) homolog (SMOH), mRNA. /FEA=mRNA /GEN=SMOH /PROD=smoothened (Drosophila) homolog /DB_XREF=gi:5032098 /UG=Hs.197366 smoothened (Drosophila) homolog /FL=gb:U84401.1 gb:NM_005631.1 gb:AF120103.1 NM_005631 smoothened, frizzled class receptor SMO 6608 NM_005631 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001570 // vasculogenesis // not recorded /// 0001649 // osteoblast differentiation // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001755 // neural crest cell migration // not recorded /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002052 // positive regulation of neuroblast proliferation // not recorded /// 0002053 // positive regulation of mesenchymal cell proliferation // not recorded /// 0003007 // heart morphogenesis // not recorded /// 0003140 // determination of left/right asymmetry in lateral mesoderm // inferred from sequence or structural similarity /// 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0007228 // positive regulation of hh target transcription factor activity // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // not recorded /// 0007368 // determination of left/right symmetry // not recorded /// 0007371 // ventral midline determination // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007494 // midgut development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010002 // cardioblast differentiation // not recorded /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0021508 // floor plate formation // not recorded /// 0021561 // facial nerve development // not recorded /// 0021696 // cerebellar cortex morphogenesis // not recorded /// 0021794 // thalamus development // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // not recorded /// 0021910 // smoothened signaling pathway involved in ventral spinal cord patterning // not recorded /// 0021938 // smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation // not recorded /// 0021953 // central nervous system neuron differentiation // not recorded /// 0021984 // adenohypophysis development // not recorded /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031017 // exocrine pancreas development // not recorded /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // not recorded /// 0031102 // neuron projection regeneration // not recorded /// 0032474 // otolith morphogenesis // not recorded /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // not recorded /// 0042693 // muscle cell fate commitment // not recorded /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043392 // negative regulation of DNA binding // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // not recorded /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048663 // neuron fate commitment // not recorded /// 0048702 // embryonic neurocranium morphogenesis // not recorded /// 0048703 // embryonic viscerocranium morphogenesis // not recorded /// 0048752 // semicircular canal morphogenesis // not recorded /// 0048846 // axon extension involved in axon guidance // not recorded /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // not recorded /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051799 // negative regulation of hair follicle development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // not recorded /// 0060248 // detection of cell density by contact stimulus involved in contact inhibition // inferred from mutant phenotype /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // not recorded /// 0061053 // somite development // inferred from sequence or structural similarity /// 0061113 // pancreas morphogenesis // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from expression pattern /// 0072285 // mesenchymal to epithelial transition involved in metanephric renal vesicle formation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation /// 2000826 // regulation of heart morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0005929 // cilium // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005113 // patched binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 218630_at NM_017777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017777.1 /DEF=Homo sapiens hypothetical protein FLJ20345 (FLJ20345), mRNA. /FEA=mRNA /GEN=FLJ20345 /PROD=hypothetical protein FLJ20345 /DB_XREF=gi:8923323 /UG=Hs.20558 hypothetical protein FLJ20345 /FL=gb:NM_017777.1 NM_017777 Meckel syndrome, type 1 MKS1 54903 NM_001165927 /// NM_017777 /// XM_005257482 /// XM_005257483 /// XM_005257484 /// XM_005257485 /// XM_005257486 /// XM_006721964 /// XM_006721965 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from electronic annotation /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218631_at NM_021732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021732.1 /DEF=Homo sapiens hypothetical protein PP5395 (PP5395), mRNA. /FEA=mRNA /GEN=PP5395 /PROD=hypothetical protein PP5395 /DB_XREF=gi:11119427 /UG=Hs.23918 hypothetical protein PP5395 /FL=gb:NM_021732.1 gb:AF241786.1 gb:BC000877.1 NM_021732 arginine vasopressin-induced 1 AVPI1 60370 NM_021732 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 218632_at NM_024602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024602.1 /DEF=Homo sapiens hypothetical protein FLJ21156 (FLJ21156), mRNA. /FEA=mRNA /GEN=FLJ21156 /PROD=hypothetical protein FLJ21156 /DB_XREF=gi:13375804 /UG=Hs.26058 hypothetical protein FLJ21156 /FL=gb:NM_024602.1 NM_024602 HECT domain containing E3 ubiquitin protein ligase 3 HECTD3 79654 NM_024602 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 218633_x_at NM_018394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018394.1 /DEF=Homo sapiens hypothetical protein FLJ11342 (FLJ11342), mRNA. /FEA=mRNA /GEN=FLJ11342 /PROD=hypothetical protein FLJ11342 /DB_XREF=gi:8923000 /UG=Hs.266514 hypothetical protein FLJ11342 /FL=gb:NM_018394.1 NM_018394 abhydrolase domain containing 10 ABHD10 55347 NM_001272069 /// NM_018394 /// NR_073570 /// NR_073571 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019391 // glucuronoside catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218634_at NM_012396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012396.1 /DEF=Homo sapiens pleckstrin homology-like domain, family A, member 3 (PHLDA3), mRNA. /FEA=mRNA /GEN=PHLDA3 /PROD=pleckstrin homology-like domain, family A,member 3 /DB_XREF=gi:6912589 /UG=Hs.268557 pleckstrin homology-like domain, family A, member 3 /FL=gb:AF151100.1 gb:NM_012396.1 NM_012396 pleckstrin homology-like domain, family A, member 3 PHLDA3 23612 NM_012396 /// NR_073080 0006915 // apoptotic process // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 218636_s_at NM_016219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016219.1 /DEF=Homo sapiens alpha 1,2-mannosidase (LOC51697), mRNA. /FEA=mRNA /GEN=LOC51697 /PROD=alpha 1,2-mannosidase /DB_XREF=gi:7706436 /UG=Hs.279881 alpha 1,2-mannosidase /FL=gb:BC002953.1 gb:AF148509.1 gb:NM_016219.1 NM_016219 mannosidase, alpha, class 1B, member 1 MAN1B1 11253 NM_016219 /// NR_045720 /// NR_045721 /// XM_006716945 /// XM_006716946 0006457 // protein folding // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0044322 // endoplasmic reticulum quality control compartment // traceable author statement 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from direct assay /// 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 218637_at NM_018439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018439.1 /DEF=Homo sapiens hypothetical protein IMPACT (IMPACT), mRNA. /FEA=mRNA /GEN=IMPACT /PROD=hypothetical protein IMPACT /DB_XREF=gi:8923818 /UG=Hs.284245 hypothetical protein IMPACT /FL=gb:AF208694.1 gb:AB026264.1 gb:NM_018439.1 NM_018439 impact RWD domain protein IMPACT 55364 NM_018439 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218638_s_at NM_012445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012445.1 /DEF=Homo sapiens spondin 2, extracellular matrix protein (SPON2), mRNA. /FEA=mRNA /GEN=SPON2 /PROD=spondin 2, extracellular matrix protein /DB_XREF=gi:6912681 /UG=Hs.288126 spondin 2, extracellular matrix protein /FL=gb:BC002707.1 gb:AB027466.1 gb:NM_012445.1 NM_012445 uncharacterized LOC100130872 /// spondin 2, extracellular matrix protein LOC100130872 /// SPON2 10417 /// 100130872 NM_001128325 /// NM_001199021 /// NM_012445 /// NR_024569 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 218639_s_at NM_025112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025112.1 /DEF=Homo sapiens hypothetical protein MGC11349 (MGC11349), mRNA. /FEA=mRNA /GEN=MGC11349 /PROD=hypothetical protein MGC11349 /DB_XREF=gi:13376684 /UG=Hs.288697 hypothetical protein MGC11349 /FL=gb:BC002940.1 gb:NM_025112.1 NM_025112 ZXD family zinc finger C ZXDC 79364 NM_001040653 /// NM_025112 /// NR_104249 /// XM_005247757 /// XM_006713741 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 218640_s_at NM_024613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024613.1 /DEF=Homo sapiens hypothetical protein FLJ13187 (FLJ13187), mRNA. /FEA=mRNA /GEN=FLJ13187 /PROD=hypothetical protein FLJ13187 /DB_XREF=gi:13375826 /UG=Hs.29724 hypothetical protein FLJ13187 /FL=gb:NM_024613.1 NM_024613 pleckstrin homology domain containing, family F (with FYVE domain) member 2 PLEKHF2 79666 NM_024613 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218641_at NM_023941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023941.1 /DEF=Homo sapiens hypothetical protein MGC3032 (MGC3032), mRNA. /FEA=mRNA /GEN=MGC3032 /PROD=hypothetical protein MGC3032 /DB_XREF=gi:13027613 /UG=Hs.300383 hypothetical protein MGC3032 /FL=gb:BC000572.1 gb:NM_023941.1 NM_023941 chromosome 11 open reading frame 95 C11orf95 65998 NM_001144936 218642_s_at NM_024300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024300.1 /DEF=Homo sapiens hypothetical protein MGC2217 (MGC2217), mRNA. /FEA=mRNA /GEN=MGC2217 /PROD=hypothetical protein MGC2217 /DB_XREF=gi:13236525 /UG=Hs.323164 hypothetical protein MGC2217 /FL=gb:BC002546.1 gb:NM_024300.1 NM_024300 coiled-coil-helix-coiled-coil-helix domain containing 7 CHCHD7 79145 NM_001011667 /// NM_001011668 /// NM_001011669 /// NM_001011670 /// NM_001011671 /// NM_024300 /// XR_428340 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 218643_s_at NM_014171 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014171.1 /DEF=Homo sapiens postsynaptic protein CRIPT (CRIPT), mRNA. /FEA=mRNA /GEN=CRIPT /PROD=HSPC139 protein /DB_XREF=gi:7661797 /UG=Hs.39733 postsynaptic protein CRIPT /FL=gb:AF161488.1 gb:NM_014171.1 NM_014171 cysteine-rich PDZ-binding protein CRIPT 9419 NM_014171 0031122 // cytoplasmic microtubule organization // inferred from sequence or structural similarity /// 0035372 // protein localization to microtubule // inferred from sequence or structural similarity /// 0045184 // establishment of protein localization // inferred from sequence or structural similarity /// 1902897 // regulation of postsynaptic density protein 95 clustering // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from sequence or structural similarity 218644_at NM_016445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016445.1 /DEF=Homo sapiens pleckstrin 2 (mouse) homolog (PLEK2), mRNA. /FEA=mRNA /GEN=PLEK2 /PROD=pleckstrin 2 (mouse) homolog /DB_XREF=gi:7706642 /UG=Hs.39957 pleckstrin 2 (mouse) homolog /FL=gb:BC001226.1 gb:AF228603.1 gb:NM_016445.1 NM_016445 pleckstrin 2 PLEK2 26499 NM_016445 0030036 // actin cytoskeleton organization // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 218645_at NM_021994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021994.1 /DEF=Homo sapiens zinc finger protein 277 (ZNF277), mRNA. /FEA=mRNA /GEN=ZNF277 /PROD=zinc finger protein 277 /DB_XREF=gi:11496268 /UG=Hs.42636 zinc finger protein 277 /FL=gb:NM_021994.1 gb:AF209198.1 NM_021994 zinc finger protein 277 ZNF277 11179 NM_021994 /// XM_005250129 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218646_at NM_017867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017867.1 /DEF=Homo sapiens hypothetical protein FLJ20534 (FLJ20534), mRNA. /FEA=mRNA /GEN=FLJ20534 /PROD=hypothetical protein FLJ20534 /DB_XREF=gi:8923502 /UG=Hs.44344 hypothetical protein FLJ20534 /FL=gb:AL136673.1 gb:NM_017867.1 NM_017867 chromosome 4 open reading frame 27 C4orf27 54969 NM_017867 0005634 // nucleus // inferred from direct assay 218647_s_at NM_024640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024640.1 /DEF=Homo sapiens hypothetical protein FLJ23476 (FLJ23476), mRNA. /FEA=mRNA /GEN=FLJ23476 /PROD=hypothetical protein FLJ23476 /DB_XREF=gi:13375875 /UG=Hs.46736 hypothetical protein FLJ23476 /FL=gb:NM_024640.1 NM_024640 yrdC N(6)-threonylcarbamoyltransferase domain containing YRDC 79693 NM_024640 0051051 // negative regulation of transport // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218648_at NM_022769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022769.1 /DEF=Homo sapiens hypothetical protein FLJ21868 (FLJ21868), mRNA. /FEA=mRNA /GEN=FLJ21868 /PROD=hypothetical protein FLJ21868 /DB_XREF=gi:12232446 /UG=Hs.46829 hypothetical protein FLJ21868 /FL=gb:NM_022769.1 NM_022769 CREB regulated transcription coactivator 3 CRTC3 64784 NM_001042574 /// NM_022769 /// XM_005254968 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0008140 // cAMP response element binding protein binding // inferred from electronic annotation 218649_x_at NM_004713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004713.1 /DEF=Homo sapiens serologically defined colon cancer antigen 1 (SDCCAG1), mRNA. /FEA=mRNA /GEN=SDCCAG1 /PROD=serologically defined colon cancer antigen 1 /DB_XREF=gi:4759077 /UG=Hs.54900 serologically defined colon cancer antigen 1 /FL=gb:AF039687.1 gb:NM_004713.1 NM_004713 nuclear export mediator factor NEMF 9147 NM_004713 /// XM_005268199 /// XM_005268200 /// XM_005268201 /// XR_429334 0044780 // bacterial-type flagellum assembly // inferred from electronic annotation /// 0051168 // nuclear export // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 218650_at NM_022775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022775.1 /DEF=Homo sapiens hypothetical protein FLJ22127 (FLJ22127), mRNA. /FEA=mRNA /GEN=FLJ22127 /PROD=hypothetical protein FLJ22127 /DB_XREF=gi:12232458 /UG=Hs.59457 hypothetical protein FLJ22127 /FL=gb:NM_022775.1 NM_022775 DGCR8 microprocessor complex subunit /// microRNA 1306 DGCR8 /// MIR1306 54487 /// 100302197 NM_001190326 /// NM_022720 /// NR_031706 /// XM_006724268 0010467 // gene expression // traceable author statement /// 0031053 // primary miRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218651_s_at NM_018357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018357.1 /DEF=Homo sapiens hypothetical protein FLJ11196 (FLJ11196), mRNA. /FEA=mRNA /GEN=FLJ11196 /PROD=hypothetical protein FLJ11196 /DB_XREF=gi:8922933 /UG=Hs.6166 hypothetical protein FLJ11196 /FL=gb:NM_018357.1 NM_018357 La ribonucleoprotein domain family, member 6 LARP6 55323 NM_001286679 /// NM_018357 /// NM_197958 0006396 // RNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 218652_s_at NM_017733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017733.1 /DEF=Homo sapiens hypothetical protein FLJ20265 (FLJ20265), mRNA. /FEA=mRNA /GEN=FLJ20265 /PROD=hypothetical protein FLJ20265 /DB_XREF=gi:8923239 /UG=Hs.7099 hypothetical protein FLJ20265 /FL=gb:BC001249.1 gb:BC000937.2 gb:NM_017733.1 NM_017733 phosphatidylinositol glycan anchor biosynthesis, class G PIGG 54872 NM_001127178 /// NM_001289051 /// NM_001289052 /// NM_001289053 /// NM_001289055 /// NM_001289057 /// NM_017733 /// NR_110293 /// XM_005272283 /// XM_005272284 /// XM_005272287 /// XM_005272288 /// XM_005272289 /// XM_006713892 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // traceable author statement /// 0051267 // CP2 mannose-ethanolamine phosphotransferase activity // inferred from direct assay 218653_at NM_014252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014252.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 (SLC25A15), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A15 /PROD=ornithine transporter 1(hyperornithinemia-hyperammonemia-homocitrullinuria) /DB_XREF=gi:7657584 /UG=Hs.78457 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 /FL=gb:BC002702.1 gb:AF112968.1 gb:NM_014252.1 NM_014252 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 SLC25A15 10166 NM_014252 0000050 // urea cycle // traceable author statement /// 0000066 // mitochondrial ornithine transport // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000064 // L-ornithine transmembrane transporter activity // traceable author statement 218654_s_at NM_016071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016071.1 /DEF=Homo sapiens CGI-139 protein (LOC51650), mRNA. /FEA=mRNA /GEN=LOC51650 /PROD=CGI-139 protein /DB_XREF=gi:7706348 /UG=Hs.83006 CGI-139 protein /FL=gb:AF151897.1 gb:AF078858.1 gb:NM_016071.1 NM_016071 mitochondrial ribosomal protein S33 MRPS33 51650 NM_016071 /// NM_053035 0006412 // translation // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 218655_s_at NM_017748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017748.1 /DEF=Homo sapiens hypothetical protein FLJ20291 (FLJ20291), mRNA. /FEA=mRNA /GEN=FLJ20291 /PROD=hypothetical protein FLJ20291 /DB_XREF=gi:8923270 /UG=Hs.8928 hypothetical protein FLJ20291 /FL=gb:NM_017748.1 NM_017748 CWC25 spliceosome-associated protein homolog (S. cerevisiae) CWC25 54883 NM_017748 /// NR_073428 /// XR_429906 /// XR_429907 /// XR_430783 /// XR_430784 218656_s_at NM_005780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005780.1 /DEF=Homo sapiens lipoma HMGIC fusion partner (LHFP), mRNA. /FEA=mRNA /GEN=LHFP /PROD=lipoma HMGIC fusion partner /DB_XREF=gi:5031864 /UG=Hs.93765 lipoma HMGIC fusion partner /FL=gb:AF098807.1 gb:NM_005780.1 NM_005780 lipoma HMGIC fusion partner LHFP 10186 NM_005780 /// XM_006719750 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement 218657_at NM_016339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016339.1 /DEF=Homo sapiens Link guanine nucleotide exchange factor II (LOC51195), mRNA. /FEA=mRNA /GEN=LOC51195 /PROD=Link guanine nucleotide exchange factor II /DB_XREF=gi:7705938 /UG=Hs.118562 Link guanine nucleotide exchange factor II /FL=gb:AF117946.1 gb:NM_016339.1 NM_016339 Rap guanine nucleotide exchange factor (GEF)-like 1 RAPGEFL1 51195 NM_016339 /// XM_006721932 /// XM_006721933 /// XM_006721934 /// XM_006721935 /// XM_006721936 /// XM_006721937 /// XM_006721938 /// XM_006721939 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 218658_s_at NM_022899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022899.1 /DEF=Homo sapiens hypothetical protein FLJ12934 (FLJ12934), mRNA. /FEA=mRNA /GEN=FLJ12934 /PROD=hypothetical protein FLJ12934 /DB_XREF=gi:12597636 /UG=Hs.124219 hypothetical protein FLJ12934 /FL=gb:NM_022899.1 NM_022899 ARP8 actin-related protein 8 homolog (yeast) ACTR8 93973 NM_022899 /// XM_005265587 /// XM_006713419 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 218659_at NM_018263 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018263.1 /DEF=Homo sapiens hypothetical protein FLJ10898 (FLJ10898), mRNA. /FEA=mRNA /GEN=FLJ10898 /PROD=hypothetical protein FLJ10898 /DB_XREF=gi:8922749 /UG=Hs.13801 KIAA1685 protein /FL=gb:NM_018263.1 NM_018263 additional sex combs like transcriptional regulator 2 ASXL2 55252 NM_018263 /// XM_006712039 /// XM_006712040 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218660_at NM_003494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003494.1 /DEF=Homo sapiens dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) (DYSF), mRNA. /FEA=mRNA /GEN=DYSF /PROD=dysferlin /DB_XREF=gi:4503430 /UG=Hs.143897 dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) /FL=gb:AF075575.1 gb:NM_003494.1 NM_003494 dysferlin DYSF 8291 NM_001130455 /// NM_001130976 /// NM_001130977 /// NM_001130978 /// NM_001130979 /// NM_001130980 /// NM_001130981 /// NM_001130982 /// NM_001130983 /// NM_001130984 /// NM_001130985 /// NM_001130986 /// NM_001130987 /// NM_003494 /// XM_005264584 /// XM_005264585 0001778 // plasma membrane repair // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030315 // T-tubule // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from mutant phenotype /// 0008289 // lipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218661_at NM_024845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024845.1 /DEF=Homo sapiens hypothetical protein FLJ14154 (FLJ14154), mRNA. /FEA=mRNA /GEN=FLJ14154 /PROD=hypothetical protein FLJ14154 /DB_XREF=gi:13376260 /UG=Hs.184870 hypothetical protein FLJ14154 /FL=gb:NM_024845.1 NM_024845 N(alpha)-acetyltransferase 60, NatF catalytic subunit NAA60 79903 NM_001083600 /// NM_001083601 /// NM_024845 /// XM_006720949 /// XM_006720950 /// XM_006720951 /// XM_006720952 0006334 // nucleosome assembly // inferred from direct assay /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017196 // N-terminal peptidyl-methionine acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 218662_s_at NM_022346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022346.1 /DEF=Homo sapiens chromosome condensation protein G (HCAP-G), mRNA. /FEA=mRNA /GEN=HCAP-G /PROD=chromosome condensation protein G /DB_XREF=gi:11641252 /UG=Hs.193602 chromosome condensation protein G /FL=gb:AF235023.1 gb:NM_022346.1 gb:AF331796.1 gb:BC000827.1 gb:AB013299.1 NM_022346 non-SMC condensin I complex, subunit G NCAPG 64151 NM_022346 /// NR_073124 /// XM_006713971 /// XM_006713972 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218663_at NM_022346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022346.1 /DEF=Homo sapiens chromosome condensation protein G (HCAP-G), mRNA. /FEA=mRNA /GEN=HCAP-G /PROD=chromosome condensation protein G /DB_XREF=gi:11641252 /UG=Hs.193602 chromosome condensation protein G /FL=gb:AF235023.1 gb:NM_022346.1 gb:AF331796.1 gb:BC000827.1 gb:AB013299.1 NM_022346 non-SMC condensin I complex, subunit G NCAPG 64151 NM_022346 /// NR_073124 /// XM_006713971 /// XM_006713972 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218664_at NM_016011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016011.1 /DEF=Homo sapiens CGI-63 protein (LOC51102), mRNA. /FEA=mRNA /GEN=LOC51102 /PROD=CGI-63 protein /DB_XREF=gi:7705776 /UG=Hs.19513 CGI-63 protein /FL=gb:BC001419.1 gb:AF151821.1 gb:NM_016011.1 NM_016011 mitochondrial trans-2-enoyl-CoA reductase MECR 51102 NM_001024732 /// NM_016011 /// XM_005245885 /// XM_005245886 /// XM_005245887 /// XM_005245888 /// XM_005245889 /// XM_006710674 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0019166 // trans-2-enoyl-CoA reductase (NADPH) activity // inferred from direct assay 218665_at NM_012193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012193.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 4 (FZD4), mRNA. /FEA=mRNA /GEN=FZD4 /PROD=frizzled (Drosophila) homolog 4 /DB_XREF=gi:6912383 /UG=Hs.19545 frizzled (Drosophila) homolog 4 /FL=gb:AB032417.1 gb:NM_012193.1 NM_012193 frizzled class receptor 4 FZD4 8322 NM_012193 0001553 // luteinization // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007223 // Wnt signaling pathway, calcium modulating pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009790 // embryo development // /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // not recorded /// 0031987 // locomotion involved in locomotory behavior // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // not recorded /// 0035426 // extracellular matrix-cell signaling // inferred from electronic annotation /// 0042701 // progesterone secretion // not recorded /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from mutant phenotype /// 0061301 // cerebellum vasculature morphogenesis // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0019955 // cytokine binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 218666_s_at NM_017919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017919.1 /DEF=Homo sapiens hypothetical protein FLJ20651 (FLJ20651), mRNA. /FEA=mRNA /GEN=FLJ20651 /PROD=hypothetical protein FLJ20651 /DB_XREF=gi:8923603 /UG=Hs.200332 hypothetical protein FLJ20651 /FL=gb:NM_017919.1 NM_017919 syntaxin 17 STX17 55014 NM_017919 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006887 // exocytosis // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0097111 // endoplasmic reticulum-Golgi intermediate compartment organization // inferred from mutant phenotype 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from sequence or structural similarity /// 0030868 // smooth endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031201 // SNARE complex // not recorded /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0000149 // SNARE binding // not recorded /// 0000149 // SNARE binding // inferred from direct assay /// 0005484 // SNAP receptor activity // not recorded /// 0005484 // SNAP receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 218667_at NM_022368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022368.1 /DEF=Homo sapiens hypothetical protein FLJ11830 similar to Praja1 (FLJ11830), mRNA. /FEA=mRNA /GEN=FLJ11830 /PROD=hypothetical protein FLJ11830 similar to Praja1 /DB_XREF=gi:11641292 /UG=Hs.21122 hypothetical protein FLJ11830 similar to Praja1 /FL=gb:NM_022368.1 NM_022368 praja ring finger 1, E3 ubiquitin protein ligase PJA1 64219 NM_001032396 /// NM_022368 /// NM_145119 /// XM_005262292 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218668_s_at NM_021183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021183.1 /DEF=Homo sapiens hypothetical protein similar to small G proteins, especially RAP-2A (LOC57826), mRNA. /FEA=mRNA /GEN=LOC57826 /PROD=hypothetical protein similar to small Gproteins, especially RAP-2A /DB_XREF=gi:10880976 /UG=Hs.225979 hypothetical protein similar to small G proteins, especially RAP-2A /FL=gb:NM_021183.1 gb:BC003403.1 NM_021183 RAP2C, member of RAS oncogene family RAP2C 57826 NM_001271186 /// NM_001271187 /// NM_021183 /// NR_073150 /// XM_006724775 /// XR_430548 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0061097 // regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 218669_at NM_021183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021183.1 /DEF=Homo sapiens hypothetical protein similar to small G proteins, especially RAP-2A (LOC57826), mRNA. /FEA=mRNA /GEN=LOC57826 /PROD=hypothetical protein similar to small Gproteins, especially RAP-2A /DB_XREF=gi:10880976 /UG=Hs.225979 hypothetical protein similar to small G proteins, especially RAP-2A /FL=gb:NM_021183.1 gb:BC003403.1 NM_021183 RAP2C, member of RAS oncogene family RAP2C 57826 NM_001271186 /// NM_001271187 /// NM_021183 /// NR_073150 /// XM_006724775 /// XR_430548 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0061097 // regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 218670_at NM_025215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025215.1 /DEF=Homo sapiens pseudouridine synthase 1 (PUS1), mRNA. /FEA=mRNA /GEN=PUS1 /PROD=pseudouridine synthase 1 /DB_XREF=gi:13376819 /UG=Hs.23723 pseudouridine synthase 1 /FL=gb:BC002901.1 gb:NM_025215.1 NM_025215 pseudouridylate synthase 1 PUS1 80324 NM_001002019 /// NM_001002020 /// NM_025215 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // non-traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0031119 // tRNA pseudouridine synthesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004730 // pseudouridylate synthase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218671_s_at NM_016311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016311.1 /DEF=Homo sapiens ATPase inhibitor precursor (LOC51189), mRNA. /FEA=mRNA /GEN=LOC51189 /PROD=ATPase inhibitor precursor /DB_XREF=gi:7705926 /UG=Hs.241336 ATPase inhibitor precursor /FL=gb:BC004955.1 gb:AB029042.1 gb:NM_016311.1 NM_016311 ATPase inhibitory factor 1 ATPIF1 93974 NM_016311 /// NM_178190 /// NM_178191 0001525 // angiogenesis // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006783 // heme biosynthetic process // inferred from mutant phenotype /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045980 // negative regulation of nucleotide metabolic process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0051346 // negative regulation of hydrolase activity // inferred from direct assay /// 0051346 // negative regulation of hydrolase activity // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0004857 // enzyme inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0042030 // ATPase inhibitor activity // inferred from direct assay /// 0042030 // ATPase inhibitor activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043532 // angiostatin binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from sequence or structural similarity 218672_at NM_024041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024041.1 /DEF=Homo sapiens hypothetical protein MGC3180 (MGC3180), mRNA. /FEA=mRNA /GEN=MGC3180 /PROD=hypothetical protein MGC3180 /DB_XREF=gi:13128997 /UG=Hs.250570 hypothetical protein MGC3180 /FL=gb:BC000264.1 gb:NM_024041.1 NM_024041 sodium channel modifier 1 /// TNFAIP8L2-SCNM1 readthrough SCNM1 /// TNFAIP8L2-SCNM1 79005 /// 100534012 NM_001002234 /// NM_001204848 /// NM_001204856 /// NM_024041 /// NR_037937 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218673_s_at NM_006395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006395.1 /DEF=Homo sapiens ubiquitin activating enzyme E1-like protein (GSA7), mRNA. /FEA=mRNA /GEN=GSA7 /PROD=ubiquitin activating enzyme E1-like protein /DB_XREF=gi:5453667 /UG=Hs.278607 ubiquitin activating enzyme E1-like protein /FL=gb:AF094516.1 gb:NM_006395.1 NM_006395 autophagy related 7 ATG7 10533 NM_001136031 /// NM_001144912 /// NM_006395 /// XM_005264803 /// XM_006712931 /// XM_006712932 /// XM_006712933 /// XM_006712934 /// XM_006712935 /// XM_006712936 0000422 // mitochondrion degradation // not recorded /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006497 // protein lipidation // inferred from direct assay /// 0006501 // C-terminal protein lipidation // not recorded /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0006996 // organelle organization // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030163 // protein catabolic process // not recorded /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0031401 // positive regulation of protein modification process // inferred from direct assay /// 0032446 // protein modification by small protein conjugation // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044805 // late nucleophagy // not recorded /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0050877 // neurological system process // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement /// 0071455 // cellular response to hyperoxia // inferred from direct assay 0000407 // pre-autophagosomal structure // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005930 // axoneme // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019778 // Atg12 activating enzyme activity // not recorded /// 0019778 // Atg12 activating enzyme activity // inferred from sequence or structural similarity /// 0019779 // Atg8 activating enzyme // not recorded /// 0042803 // protein homodimerization activity // inferred from direct assay 218674_at NM_024941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024941.1 /DEF=Homo sapiens hypothetical protein FLJ13611 (FLJ13611), mRNA. /FEA=mRNA /GEN=FLJ13611 /PROD=hypothetical protein FLJ13611 /DB_XREF=gi:13376418 /UG=Hs.282958 hypothetical protein FLJ13611 /FL=gb:NM_024941.1 NM_024941 trafficking protein particle complex 13 TRAPPC13 80006 NM_001093755 /// NM_001093756 /// NM_001243737 /// NM_024941 /// NR_003545 0005515 // protein binding // inferred from physical interaction 218675_at NM_020372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020372.1 /DEF=Homo sapiens organic cation transporter (LOC57100), mRNA. /FEA=mRNA /GEN=LOC57100 /PROD=organic cation transporter /DB_XREF=gi:9966842 /UG=Hs.283404 organic cation transporter /FL=gb:NM_020372.1 NM_020372 solute carrier family 22, member 17 SLC22A17 51310 NM_001289050 /// NM_016609 /// NM_020372 /// NR_110290 /// XM_005267747 /// XM_005267748 /// XR_245694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0015891 // siderophore transport // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031301 // integral component of organelle membrane // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 218676_s_at NM_021213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021213.1 /DEF=Homo sapiens phosphatidylcholine transfer protein (PCTP), mRNA. /FEA=mRNA /GEN=PCTP /PROD=phosphatidylcholine transfer protein /DB_XREF=gi:10864026 /UG=Hs.285218 phosphatidylcholine transfer protein /FL=gb:NM_021213.1 gb:AF151638.1 NM_021213 phosphatidylcholine transfer protein PCTP 58488 NM_001102402 /// NM_021213 /// XM_005257549 /// XM_005257550 /// XM_005257551 /// XR_243677 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // non-traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // inferred from direct assay /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0031210 // phosphatidylcholine binding // inferred from direct assay 218677_at NM_020672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020672.1 /DEF=Homo sapiens S100-type calcium binding protein A14 (LOC57402), mRNA. /FEA=mRNA /GEN=LOC57402 /PROD=S100-type calcium binding protein A14 /DB_XREF=gi:10190711 /UG=Hs.288998 S100-type calcium binding protein A14 /FL=gb:NM_020672.1 gb:BC005019.1 gb:AY007220.1 NM_020672 S100 calcium binding protein A14 S100A14 57402 NM_020672 /// XM_005245362 /// XM_006711468 0006915 // apoptotic process // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0034142 // toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from expression pattern /// 0055074 // calcium ion homeostasis // non-traceable author statement /// 0071624 // positive regulation of granulocyte chemotaxis // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0042379 // chemokine receptor binding // inferred from mutant phenotype 218678_at NM_024609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024609.1 /DEF=Homo sapiens hypothetical protein FLJ21841 (FLJ21841), mRNA. /FEA=mRNA /GEN=FLJ21841 /PROD=hypothetical protein FLJ21841 /DB_XREF=gi:13375818 /UG=Hs.29076 hypothetical protein FLJ21841 /FL=gb:NM_024609.1 NM_024609 nestin NES 10763 NM_006617 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0007420 // brain development // inferred from sequence or structural similarity /// 0030844 // positive regulation of intermediate filament depolymerization // inferred from sequence or structural similarity /// 0031076 // embryonic camera-type eye development // inferred from sequence or structural similarity /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048858 // cell projection morphogenesis // inferred from electronic annotation /// 0072089 // stem cell proliferation // inferred from mutant phenotype /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // non-traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from sequence or structural similarity 218679_s_at NM_016208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016208.1 /DEF=Homo sapiens VPS28 protein (LOC51160), mRNA. /FEA=mRNA /GEN=LOC51160 /PROD=VPS28 protein /DB_XREF=gi:7705884 /UG=Hs.293441 VPS28 protein /FL=gb:AF316887.1 gb:AF182844.1 gb:NM_016208.1 NM_016208 vacuolar protein sorting 28 homolog (S. cerevisiae) VPS28 51160 NM_016208 /// NM_183057 /// XM_005272323 /// XM_005272324 /// XM_005272325 /// XM_006716577 /// XM_006716578 /// XM_006716579 /// XM_006716580 /// XM_006716581 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0000813 // ESCRT I complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218680_x_at NM_016400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016400.1 /DEF=Homo sapiens Huntingtin interacting protein K (HYPK), mRNA. /FEA=mRNA /GEN=HYPK /PROD=Huntingtin interacting protein K /DB_XREF=gi:7705468 /UG=Hs.300954 Huntingtin interacting protein K /FL=gb:AF161485.1 gb:NM_016400.1 NM_016400 huntingtin interacting protein K /// microRNA 1282 /// small EDRK-rich factor 2 /// SERF2-C15orf63 readthrough HYPK /// MIR1282 /// SERF2 /// SERF2-C15ORF63 10169 /// 25764 /// 100302254 /// 100529067 NM_001018108 /// NM_001199875 /// NM_001199876 /// NM_001199877 /// NM_001199878 /// NM_001199885 /// NM_005770 /// NM_016400 /// NR_031695 /// NR_037672 /// NR_037673 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218681_s_at NM_022044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022044.1 /DEF=Homo sapiens stromal cell-derived factor 2-like 1 (SDF2L1), mRNA. /FEA=mRNA /GEN=SDF2L1 /PROD=stromal cell-derived factor 2-like 1 /DB_XREF=gi:11545742 /UG=Hs.303116 stromal cell-derived factor 2-like 1 /FL=gb:AB043007.1 gb:NM_022044.1 NM_022044 stromal cell-derived factor 2-like 1 SDF2L1 23753 NM_022044 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation 218682_s_at NM_018158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018158.1 /DEF=Homo sapiens hypothetical protein FLJ10624 (FLJ10624), mRNA. /FEA=mRNA /GEN=FLJ10624 /PROD=hypothetical protein FLJ10624 /DB_XREF=gi:8922556 /UG=Hs.306000 hypothetical protein FLJ10624 /FL=gb:NM_018158.1 NM_018158 solute carrier family 4 (anion exchanger), member 1, adaptor protein SLC4A1AP 22950 NM_018158 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218683_at NM_021190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021190.1 /DEF=Homo sapiens neural polypyrimidine tract binding protein (PTB), mRNA. /FEA=mRNA /GEN=PTB /PROD=neural polypyrimidine tract binding protein /DB_XREF=gi:10863996 /UG=Hs.34956 neural polypyrimidine tract binding protein /FL=gb:NM_021190.1 gb:AF176085.1 NM_021190 polypyrimidine tract binding protein 2 PTBP2 58155 NM_021190 /// XM_005271084 /// XM_005271085 /// XM_005271086 /// XR_246284 /// XR_246285 /// XR_246286 /// XR_246287 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218684_at NM_018103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018103.1 /DEF=Homo sapiens hypothetical protein FLJ10470 (FLJ10470), mRNA. /FEA=mRNA /GEN=FLJ10470 /PROD=hypothetical protein FLJ10470 /DB_XREF=gi:8922441 /UG=Hs.44672 hypothetical protein FLJ10470 /FL=gb:NM_018103.1 NM_018103 leucine rich repeat containing 8 family, member D LRRC8D 55144 NM_001134479 /// NM_018103 /// XM_005270991 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218685_s_at NM_014311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014311.1 /DEF=Homo sapiens single-strand selective monofunctional uracil DNA glycosylase (SMUG1), mRNA. /FEA=mRNA /GEN=SMUG1 /PROD=single-strand selective monofunctional uracilDNA glycosylase /DB_XREF=gi:7657596 /UG=Hs.5212 single-strand selective monofunctional uracil DNA glycosylase /FL=gb:AF125182.1 gb:NM_014311.1 NM_014311 single-strand-selective monofunctional uracil-DNA glycosylase 1 SMUG1 23583 NM_001243787 /// NM_001243788 /// NM_001243789 /// NM_001243790 /// NM_001243791 /// NM_014311 /// NR_045039 /// XM_006719319 /// XM_006719320 /// XM_006719321 /// XM_006719322 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045008 // depyrimidination // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000703 // oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004844 // uracil DNA N-glycosylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0017065 // single-strand selective uracil DNA N-glycosylase activity // inferred from direct assay /// 0019104 // DNA N-glycosylase activity // inferred from direct assay 218686_s_at NM_022450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022450.1 /DEF=Homo sapiens hypothetical protein FLJ22357 similar to epidermal growth factor receptor-related protein (FLJ22357), mRNA. /FEA=mRNA /GEN=FLJ22357 /PROD=hypothetical protein FLJ22357 similar toepidermal growth factor receptor-related protein /DB_XREF=gi:11967982 /UG=Hs.57988 hypothetical protein FLJ22357 similar to epidermal growth factor receptor-related protein /FL=gb:NM_022450.1 NM_022450 rhomboid 5 homolog 1 (Drosophila) RHBDF1 64285 NM_022450 /// XM_005255494 /// XM_005255498 /// XM_006720918 /// XM_006720919 /// XM_006720920 /// XM_006720921 /// XM_006720922 /// XR_429644 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050708 // regulation of protein secretion // inferred from mutant phenotype /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0019838 // growth factor binding // inferred from electronic annotation 218687_s_at NM_017648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017648.1 /DEF=Homo sapiens hypothetical protein FLJ20063 (FLJ20063), mRNA. /FEA=mRNA /GEN=FLJ20063 /PROD=hypothetical protein FLJ20063 /DB_XREF=gi:8923068 /UG=Hs.5940 hypothetical protein FLJ20063 /FL=gb:AB035807.1 gb:NM_017648.1 NM_017648 mucin 13, cell surface associated MUC13 56667 NM_033049 0016266 // O-glycan processing // traceable author statement /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042803 // protein homodimerization activity // inferred from direct assay 218688_at NM_015533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015533.1 /DEF=Homo sapiens DKFZP586B1621 protein (DKFZP586B1621), mRNA. /FEA=mRNA /GEN=DKFZP586B1621 /PROD=DKFZP586B1621 protein /DB_XREF=gi:13027381 /UG=Hs.6278 DKFZP586B1621 protein /FL=gb:BC001341.1 gb:NM_015533.1 NM_015533 dihydroxyacetone kinase 2 homolog (S. cerevisiae) DAK 26007 NM_015533 /// XM_005273898 /// XM_005273899 /// XM_006718496 /// XM_006718497 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045088 // regulation of innate immune response // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004371 // glycerone kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0034012 // FAD-AMP lyase (cyclizing) activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050354 // triokinase activity // inferred from direct assay 218689_at NM_022725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022725.1 /DEF=Homo sapiens Fanconi anemia, complementation group F (FANCF), mRNA. /FEA=mRNA /GEN=FANCF /PROD=Fanconi anemia, complementation group F /DB_XREF=gi:12232376 /UG=Hs.65328 Fanconi anemia, complementation group F /FL=gb:NM_022725.1 gb:AF181994.1 gb:AF181995.1 NM_022725 Fanconi anemia, complementation group F FANCF 2188 NM_022725 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218690_at NM_003687 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003687.1 /DEF=Homo sapiens LIM domain protein (RIL), mRNA. /FEA=mRNA /GEN=RIL /PROD=LIM domain protein /DB_XREF=gi:4506530 /UG=Hs.79691 LIM domain protein /FL=gb:NM_003687.1 gb:AF154335.1 gb:AF153882.1 NM_003687 PDZ and LIM domain 4 PDLIM4 8572 NM_001131027 /// NM_003687 /// XM_006714723 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218691_s_at AF153882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF153882.1 /DEF=Homo sapiens reversion-induced LIM protein (RIL) mRNA, complete cds. /FEA=mRNA /GEN=RIL /PROD=reversion-induced LIM protein /DB_XREF=gi:5020415 /UG=Hs.79691 LIM domain protein /FL=gb:NM_003687.1 gb:AF154335.1 gb:AF153882.1 AF153882 PDZ and LIM domain 4 PDLIM4 8572 NM_001131027 /// NM_003687 /// XM_006714723 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218692_at NM_017786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017786.1 /DEF=Homo sapiens hypothetical protein FLJ20366 (FLJ20366), mRNA. /FEA=mRNA /GEN=FLJ20366 /PROD=hypothetical protein FLJ20366 /DB_XREF=gi:8923340 /UG=Hs.8358 hypothetical protein FLJ20366 /FL=gb:NM_017786.1 NM_017786 syntabulin (syntaxin-interacting) SYBU 55638 NM_001099743 /// NM_001099744 /// NM_001099745 /// NM_001099746 /// NM_001099747 /// NM_001099748 /// NM_001099749 /// NM_001099750 /// NM_001099751 /// NM_001099752 /// NM_001099753 /// NM_001099754 /// NM_001099755 /// NM_001099756 /// NM_017786 /// XM_005250999 /// XM_005251000 /// XM_006716600 /// XM_006716601 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097433 // dense body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from electronic annotation 218693_at NM_012339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012339.1 /DEF=Homo sapiens transmembrane 4 superfamily member (tetraspan NET-7) (NET-7), mRNA. /FEA=mRNA /GEN=NET-7 /PROD=transmembrane 4 superfamily member (tetraspanNET-7) /DB_XREF=gi:6912529 /UG=Hs.95583 transmembrane 4 superfamily member (tetraspan NET-7) /FL=gb:BC003157.1 gb:BC004161.1 gb:AF120266.1 gb:NM_012339.1 NM_012339 tetraspanin 15 TSPAN15 23555 NM_012339 /// XM_005269666 /// XM_005269667 /// XM_006717738 0008593 // regulation of Notch signaling pathway // inferred from mutant phenotype /// 0051604 // protein maturation // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 218694_at NM_016608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016608.1 /DEF=Homo sapiens ALEX1 protein (LOC51309), mRNA. /FEA=mRNA /GEN=LOC51309 /PROD=ALEX1 protein /DB_XREF=gi:7706142 /UG=Hs.9728 ALEX1 protein /FL=gb:AF248963.1 gb:BC002691.1 gb:AB039670.1 gb:NM_016608.1 NM_016608 armadillo repeat containing, X-linked 1 ARMCX1 51309 NM_016608 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218695_at NM_019037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019037.1 /DEF=Homo sapiens hypothetical protein (FLJ20591), mRNA. /FEA=mRNA /GEN=FLJ20591 /PROD=hypothetical protein /DB_XREF=gi:9506688 /UG=Hs.97574 exosome component Rrp41 /FL=gb:BC002777.1 gb:AF281133.1 gb:NM_019037.1 NM_019037 exosome component 4 EXOSC4 54512 NM_019037 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006364 // rRNA processing // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0045006 // DNA deamination // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071028 // nuclear mRNA surveillance // inferred from mutant phenotype /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // non-traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035327 // transcriptionally active chromatin // inferred from mutant phenotype 0000175 // 3'-5'-exoribonuclease activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay 218696_at NM_004836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004836.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3), mRNA. /FEA=mRNA /GEN=EIF2AK3 /PROD=eukaryotic translation initiation factor 2-alphakinase 3 /DB_XREF=gi:4758891 /UG=Hs.102506 eukaryotic translation initiation factor 2-alpha kinase 3 /FL=gb:AF110146.1 gb:NM_004836.1 gb:AF193339.1 NM_004836 eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 9451 NM_004836 /// XM_005264649 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from mutant phenotype /// 0002063 // chondrocyte development // inferred from sequence or structural similarity /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from direct assay /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // traceable author statement /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from sequence or structural similarity /// 0030073 // insulin secretion // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from mutant phenotype /// 0031642 // negative regulation of myelination // inferred from sequence or structural similarity /// 0032055 // negative regulation of translation in response to stress // inferred from electronic annotation /// 0032057 // negative regulation of translational initiation in response to stress // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from mutant phenotype /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005623 // cell // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred by curator /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218697_at NM_016453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016453.1 /DEF=Homo sapiens SH3 protein (AF3P21), mRNA. /FEA=mRNA /GEN=AF3P21 /PROD=SH3 protein /DB_XREF=gi:7705265 /UG=Hs.102929 SH3 protein /FL=gb:AF303581.1 gb:AF178432.1 gb:NM_016453.1 NM_016453 NCK interacting protein with SH3 domain NCKIPSD 51517 NM_016453 /// NM_184231 /// XM_005265223 /// XM_006713205 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // non-traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 218698_at NM_015957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015957.1 /DEF=Homo sapiens CGI-29 protein (LOC51074), mRNA. /FEA=mRNA /GEN=LOC51074 /PROD=CGI-29 protein /DB_XREF=gi:7705723 /UG=Hs.104058 CGI-29 protein /FL=gb:AF132963.1 gb:NM_015957.1 NM_015957 APAF1 interacting protein APIP 51074 NM_015957 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0019284 // L-methionine biosynthetic process from S-adenosylmethionine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from electronic annotation /// 0019509 // L-methionine salvage from methylthioadenosine // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046570 // methylthioribulose 1-phosphate dehydratase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218699_at BG338251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG338251 /FEA=EST /DB_XREF=gi:13144689 /DB_XREF=est:602435412F1 /CLONE=IMAGE:4553498 /UG=Hs.115325 RAB7, member RAS oncogene family-like 1 /FL=gb:BC002585.1 gb:D84488.1 gb:NM_003929.1 BG338251 RAB29, member RAS oncogene family RAB29 8934 NM_001135662 /// NM_001135663 /// NM_001135664 /// NM_003929 /// XM_005245569 /// XM_005245570 /// XM_005245571 /// XM_006711602 /// XM_006711603 /// XM_006711604 /// XM_006711605 /// XM_006711606 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035526 // retrograde transport, plasma membrane to Golgi // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218700_s_at BC002585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002585.1 /DEF=Homo sapiens, RAB7, member RAS oncogene family-like 1, clone MGC:1653, mRNA, complete cds. /FEA=mRNA /PROD=RAB7, member RAS oncogene family-like 1 /DB_XREF=gi:12803516 /UG=Hs.115325 RAB7, member RAS oncogene family-like 1 /FL=gb:BC002585.1 gb:D84488.1 gb:NM_003929.1 BC002585 RAB29, member RAS oncogene family RAB29 8934 NM_001135662 /// NM_001135663 /// NM_001135664 /// NM_003929 /// XM_005245569 /// XM_005245570 /// XM_005245571 /// XM_006711602 /// XM_006711603 /// XM_006711604 /// XM_006711605 /// XM_006711606 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035526 // retrograde transport, plasma membrane to Golgi // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218701_at NM_016027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016027.1 /DEF=Homo sapiens CGI-83 protein (LOC51110), mRNA. /FEA=mRNA /GEN=LOC51110 /PROD=CGI-83 protein /DB_XREF=gi:7705792 /UG=Hs.118554 CGI-83 protein /FL=gb:BC000878.1 gb:AF151841.1 gb:NM_016027.1 NM_016027 lactamase, beta 2 LACTB2 51110 NM_016027 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218702_at NM_017827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017827.1 /DEF=Homo sapiens hypothetical protein FLJ20450 (FLJ20450), mRNA. /FEA=mRNA /GEN=FLJ20450 /PROD=hypothetical protein FLJ20450 /DB_XREF=gi:8923420 /UG=Hs.14220 hypothetical protein FLJ20450 /FL=gb:NM_017827.1 gb:AB029948.1 NM_017827 seryl-tRNA synthetase 2, mitochondrial SARS2 54938 NM_001145901 /// NM_017827 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006434 // seryl-tRNA aminoacylation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0097056 // selenocysteinyl-tRNA(Sec) biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // inferred from sequence or structural similarity /// 0004828 // serine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218703_at NM_012430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012430.1 /DEF=Homo sapiens sec22 homolog (SEC22A), mRNA. /FEA=mRNA /GEN=SEC22A /PROD=sec22 homolog /DB_XREF=gi:6912647 /UG=Hs.183655 sec22 homolog /FL=gb:AF100749.1 gb:NM_012430.1 NM_012430 SEC22 vesicle trafficking protein homolog A (S. cerevisiae) SEC22A 26984 NM_012430 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048280 // vesicle fusion with Golgi apparatus // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded 0000149 // SNARE binding // not recorded /// 0005215 // transporter activity // traceable author statement /// 0005484 // SNAP receptor activity // not recorded 218704_at NM_017763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017763.1 /DEF=Homo sapiens hypothetical protein FLJ20315 (FLJ20315), mRNA. /FEA=mRNA /GEN=FLJ20315 /PROD=hypothetical protein FLJ20315 /DB_XREF=gi:8923298 /UG=Hs.18457 hypothetical protein FLJ20315 /FL=gb:NM_017763.1 NM_017763 ring finger protein 43 RNF43 54894 NM_017763 0007165 // signal transduction // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0038018 // Wnt receptor catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0072089 // stem cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218705_s_at NM_014035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014035.1 /DEF=Homo sapiens SBBI31 protein (SBBI31), mRNA. /FEA=mRNA /GEN=SBBI31 /PROD=SBBI31 protein /DB_XREF=gi:7662654 /UG=Hs.184668 SBBI31 protein /FL=gb:AF139461.1 gb:NM_014035.1 NM_014035 sorting nexin 24 SNX24 28966 NM_014035 /// XM_005271972 /// XM_006714592 /// XM_006714593 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 218706_s_at AW575493 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW575493 /FEA=EST /DB_XREF=gi:7247032 /DB_XREF=est:UI-HF-BM0-adp-a-04-0-UI.s1 /CLONE=IMAGE:3062287 /UG=Hs.235445 hypothetical protein FLJ21313 /FL=gb:NM_023927.1 AW575493 GRAM domain containing 3 GRAMD3 65983 NM_001146319 /// NM_001146320 /// NM_001146321 /// NM_001146322 /// NM_023927 /// XM_005272057 /// XM_005272058 /// XM_005272059 /// XM_005272060 /// XM_005272061 /// XM_005272062 /// XM_005272063 /// XM_005272064 /// XM_005272065 0005881 // cytoplasmic microtubule // inferred from direct assay 218707_at NM_018337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018337.1 /DEF=Homo sapiens hypothetical protein FLJ11137 (FLJ11137), mRNA. /FEA=mRNA /GEN=FLJ11137 /PROD=hypothetical protein FLJ11137 /DB_XREF=gi:8922893 /UG=Hs.24545 hypothetical protein FLJ11137 /FL=gb:NM_018337.1 NM_018337 zinc finger protein 444 ZNF444 55311 NM_001253792 /// NM_018337 /// XM_005259034 /// XM_005259035 /// XM_005259036 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218708_at NM_013248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013248.1 /DEF=Homo sapiens NTF2-related export protein 1 (NXT1), mRNA. /FEA=mRNA /GEN=NXT1 /PROD=NTF2-related export protein 1 /DB_XREF=gi:7019470 /UG=Hs.24563 NTF2-related export protein 1 /FL=gb:BC000759.1 gb:BC002687.1 gb:BC003029.1 gb:BC003410.1 gb:AF156957.1 gb:NM_013248.1 NM_013248 nuclear transport factor 2-like export factor 1 NXT1 29107 NM_013248 0006405 // RNA export from nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation 218709_s_at NM_016004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016004.1 /DEF=Homo sapiens CGI-53 protein (LOC51098), mRNA. /FEA=mRNA /GEN=LOC51098 /PROD=CGI-53 protein /DB_XREF=gi:7705768 /UG=Hs.24994 CGI-53 protein /FL=gb:AF151811.1 gb:NM_016004.1 NM_016004 intraflagellar transport 52 homolog (Chlamydomonas) IFT52 51098 NM_016004 /// XM_005260417 0001841 // neural tube formation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation 0005929 // cilium // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044292 // dendrite terminus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity 218710_at NM_017735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017735.1 /DEF=Homo sapiens hypothetical protein FLJ20272 (FLJ20272), mRNA. /FEA=mRNA /GEN=FLJ20272 /PROD=hypothetical protein FLJ20272 /DB_XREF=gi:8923244 /UG=Hs.26090 hypothetical protein FLJ20272 /FL=gb:BC001248.1 gb:NM_017735.1 NM_017735 tetratricopeptide repeat domain 27 TTC27 55622 NM_001193509 /// NM_017735 /// XM_005264416 0005515 // protein binding // inferred from electronic annotation 218711_s_at NM_004657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004657.1 /DEF=Homo sapiens serum deprivation response (phosphatidylserine-binding protein) (SDPR), mRNA. /FEA=mRNA /GEN=SDPR /PROD=serum deprivation response(phosphatidylserine-binding protein) /DB_XREF=gi:4759081 /UG=Hs.26530 serum deprivation response (phosphatidylserine-binding protein) /FL=gb:AF085481.1 gb:NM_004657.1 NM_004657 serum deprivation response SDPR 8436 NM_004657 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 218712_at NM_017850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017850.1 /DEF=Homo sapiens hypothetical protein FLJ20508 (FLJ20508), mRNA. /FEA=mRNA /GEN=FLJ20508 /PROD=hypothetical protein FLJ20508 /DB_XREF=gi:8923468 /UG=Hs.272673 hypothetical protein FLJ20508 /FL=gb:NM_017850.1 NM_017850 chromosome 1 open reading frame 109 C1orf109 54955 NM_017850 /// XM_005270975 /// XM_005270977 /// XM_005270978 /// XM_005270979 /// XM_005270980 /// XM_005270981 /// XM_005270982 /// XM_005270984 /// XM_006710713 /// XM_006710714 218713_at NM_024611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024611.1 /DEF=Homo sapiens hypothetical protein FLJ11896 (FLJ11896), mRNA. /FEA=mRNA /GEN=FLJ11896 /PROD=hypothetical protein FLJ11896 /DB_XREF=gi:13375822 /UG=Hs.29263 hypothetical protein FLJ11896 /FL=gb:NM_024611.1 NM_024611 interactor of little elongator complex ELL subunit 2 ICE2 79664 NM_001018089 /// NM_001276385 /// NM_024611 /// XM_005254661 /// XM_005254662 /// XM_005254663 0005634 // nucleus // inferred from electronic annotation 218714_at NM_024031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024031.1 /DEF=Homo sapiens hypothetical protein MGC3121 (MGC3121), mRNA. /FEA=mRNA /GEN=MGC3121 /PROD=hypothetical protein MGC3121 /DB_XREF=gi:13128979 /UG=Hs.293629 hypothetical protein MGC3121 /FL=gb:BC000119.1 gb:NM_024031.1 NM_024031 proline rich 14 PRR14 78994 NM_024031 /// XM_005255566 218715_at NM_018428 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018428.1 /DEF=Homo sapiens hepatocellular carcinoma-associated antigen 66 (HCA66), mRNA. /FEA=mRNA /GEN=HCA66 /PROD=hepatocellular carcinoma-associated antigen 66 /DB_XREF=gi:8923721 /UG=Hs.30670 hepatocellular carcinoma-associated antigen 66 /FL=gb:AF244135.1 gb:AF116631.1 gb:NM_018428.1 NM_018428 UTP6, small subunit (SSU) processome component, homolog (yeast) UTP6 55813 NM_018428 /// XM_005258012 /// XR_243780 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 218716_x_at NM_012123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012123.1 /DEF=Homo sapiens CGI-02 protein (CGI-02), mRNA. /FEA=mRNA /GEN=CGI-02 /PROD=CGI-02 protein /DB_XREF=gi:6912299 /UG=Hs.33979 CGI-02 protein /FL=gb:AF319422.1 gb:AF132937.1 gb:NM_012123.1 NM_012123 mitochondrial tRNA translation optimization 1 MTO1 25821 NM_001123226 /// NM_012123 /// NM_133645 /// XM_006715444 /// XM_006715445 /// XM_006715446 /// XM_006715447 /// XM_006715448 /// XM_006715449 0002098 // tRNA wobble uridine modification // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070899 // mitochondrial tRNA wobble uridine modification // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 218717_s_at NM_018192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018192.1 /DEF=Homo sapiens hypothetical protein FLJ10718 (FLJ10718), mRNA. /FEA=mRNA /GEN=FLJ10718 /PROD=hypothetical protein FLJ10718 /DB_XREF=gi:8922618 /UG=Hs.42824 hypothetical protein FLJ10718 /FL=gb:NM_018192.1 NM_018192 leprecan-like 1 LEPREL1 55214 NM_001134418 /// NM_018192 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0019511 // peptidyl-proline hydroxylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032963 // collagen metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0019797 // procollagen-proline 3-dioxygenase activity // inferred from direct assay /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 218718_at NM_016205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016205.1 /DEF=Homo sapiens platelet derived growth factor C (PDGFC), mRNA. /FEA=mRNA /GEN=PDGFC /PROD=secretory growth factor-like protein fallotein /DB_XREF=gi:9994186 /UG=Hs.43080 platelet derived growth factor C /FL=gb:AF091434.1 gb:AF244813.1 gb:AB033831.1 gb:NM_016205.1 NM_016205 platelet derived growth factor C PDGFC 56034 NM_016205 /// NR_036641 /// XM_006714273 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 218719_s_at NM_022770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022770.1 /DEF=Homo sapiens hypothetical protein FLJ13912 (FLJ13912), mRNA. /FEA=mRNA /GEN=FLJ13912 /PROD=hypothetical protein FLJ13912 /DB_XREF=gi:12232448 /UG=Hs.47125 hypothetical protein FLJ13912 /FL=gb:NM_022770.1 NM_022770 GINS complex subunit 3 (Psf3 homolog) GINS3 64785 NM_001126129 /// NM_001126130 /// NM_022770 0006260 // DNA replication // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 218720_x_at NM_012410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012410.1 /DEF=Homo sapiens type I transmembrane receptor (seizure-related protein) (PSK-1), mRNA. /FEA=mRNA /GEN=PSK-1 /PROD=type I transmembrane receptor (seizure-relatedprotein) /DB_XREF=gi:6912611 /UG=Hs.6314 type I transmembrane receptor (seizure-related protein) /FL=gb:NM_012410.1 NM_012410 seizure related 6 homolog (mouse)-like 2 SEZ6L2 26470 NM_001114099 /// NM_001114100 /// NM_001243332 /// NM_001243333 /// NM_012410 /// NM_201575 /// XM_005255252 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 218721_s_at NM_017847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017847.1 /DEF=Homo sapiens hypothetical protein FLJ20505 (FLJ20505), mRNA. /FEA=mRNA /GEN=FLJ20505 /PROD=hypothetical protein FLJ20505 /DB_XREF=gi:8923461 /UG=Hs.69388 hypothetical protein FLJ20505 /FL=gb:BC003397.1 gb:NM_017847.1 NM_017847 chromosome 1 open reading frame 27 C1orf27 54953 NM_001164245 /// NM_001164246 /// NM_017847 /// XM_006711399 /// XM_006711400 /// XR_241088 /// XR_241089 /// XR_426787 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 218722_s_at NM_024661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024661.1 /DEF=Homo sapiens hypothetical protein FLJ12436 (FLJ12436), mRNA. /FEA=mRNA /GEN=FLJ12436 /PROD=hypothetical protein FLJ12436 /DB_XREF=gi:13375914 /UG=Hs.69485 hypothetical protein FLJ12436 /FL=gb:NM_024661.1 NM_024661 coiled-coil domain containing 51 CCDC51 79714 NM_001256964 /// NM_001256965 /// NM_001256966 /// NM_001256967 /// NM_001256968 /// NM_001256969 /// NM_024661 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218723_s_at NM_014059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014059.1 /DEF=Homo sapiens RGC32 protein (RGC32), mRNA. /FEA=mRNA /GEN=RGC32 /PROD=RGC32 protein /DB_XREF=gi:7662650 /UG=Hs.76640 RGC32 protein /FL=gb:AF036549.1 gb:NM_014059.1 NM_014059 regulator of cell cycle RGCC 28984 NM_014059 0001100 // negative regulation of exit from mitosis // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0003331 // positive regulation of extracellular matrix constituent secretion // inferred from direct assay /// 0006956 // complement activation // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0050710 // negative regulation of cytokine secretion // inferred from mutant phenotype /// 0050715 // positive regulation of cytokine secretion // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from direct assay /// 0072537 // fibroblast activation // inferred from sequence or structural similarity /// 0090272 // negative regulation of fibroblast growth factor production // inferred from direct assay /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from direct assay /// 1901991 // negative regulation of mitotic cell cycle phase transition // inferred from direct assay /// 2000048 // negative regulation of cell-cell adhesion mediated by cadherin // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction 218724_s_at NM_021809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021809.1 /DEF=Homo sapiens TGF(beta)-induced transcription factor 2 (TGIF2), mRNA. /FEA=mRNA /GEN=TGIF2 /PROD=TGF(beta)-induced transcription factor 2 /DB_XREF=gi:11141880 /UG=Hs.94785 TGF(beta)-induced transcription factor 2 /FL=gb:AB042646.1 gb:NM_021809.1 NM_021809 TGFB-induced factor homeobox 2 TGIF2 60436 NM_001199513 /// NM_001199514 /// NM_001199515 /// NM_021809 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218725_at NM_024698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024698.1 /DEF=Homo sapiens hypothetical protein FLJ13044 (FLJ13044), mRNA. /FEA=mRNA /GEN=FLJ13044 /PROD=hypothetical protein FLJ13044 /DB_XREF=gi:13375982 /UG=Hs.99486 hypothetical protein FLJ13044 /FL=gb:NM_024698.1 NM_024698 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 SLC25A22 79751 NM_001191060 /// NM_001191061 /// NM_024698 0006810 // transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation 218726_at NM_018410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018410.1 /DEF=Homo sapiens hypothetical protein DKFZp762E1312 (DKFZp762E1312), mRNA. /FEA=mRNA /GEN=DKFZp762E1312 /PROD=hypothetical protein DKFZp762E1312 /DB_XREF=gi:8922180 /UG=Hs.104859 hypothetical protein DKFZp762E1312 /FL=gb:BC001940.1 gb:NM_018410.1 NM_018410 Holliday junction recognition protein HJURP 55355 NM_001282962 /// NM_001282963 /// NM_018410 0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0034080 // centromere-specific nucleosome assembly // inferred from mutant phenotype /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0051101 // regulation of DNA binding // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218727_at NM_018231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018231.1 /DEF=Homo sapiens hypothetical protein FLJ10815 (FLJ10815), mRNA. /FEA=mRNA /GEN=FLJ10815 /PROD=hypothetical protein FLJ10815 /DB_XREF=gi:8922691 /UG=Hs.10499 hypothetical protein FLJ10815 /FL=gb:BC001961.1 gb:NM_018231.1 NM_018231 solute carrier family 38, member 7 SLC38A7 55238 NM_018231 /// XM_006721229 /// XR_429722 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from electronic annotation /// 0006867 // asparagine transport // inferred from electronic annotation /// 0006868 // glutamine transport // inferred from electronic annotation /// 0015803 // branched-chain amino acid transport // inferred from electronic annotation /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0015808 // L-alanine transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015817 // histidine transport // inferred from electronic annotation /// 0015821 // methionine transport // inferred from electronic annotation /// 0015825 // L-serine transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005290 // L-histidine transmembrane transporter activity // inferred from electronic annotation /// 0005313 // L-glutamate transmembrane transporter activity // inferred from electronic annotation /// 0015179 // L-amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015180 // L-alanine transmembrane transporter activity // inferred from electronic annotation /// 0015182 // L-asparagine transmembrane transporter activity // inferred from electronic annotation /// 0015183 // L-aspartate transmembrane transporter activity // inferred from electronic annotation /// 0015186 // L-glutamine transmembrane transporter activity // inferred from sequence or structural similarity /// 0015190 // L-leucine transmembrane transporter activity // inferred from electronic annotation /// 0015191 // L-methionine transmembrane transporter activity // inferred from electronic annotation /// 0015194 // L-serine transmembrane transporter activity // inferred from electronic annotation 218728_s_at NM_014184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014184.1 /DEF=Homo sapiens HSPC163 protein (HSPC163), mRNA. /FEA=mRNA /GEN=HSPC163 /PROD=HSPC163 protein /DB_XREF=gi:7661823 /UG=Hs.108854 HSPC163 protein /FL=gb:BC000573.1 gb:AF161512.1 gb:NM_014184.1 NM_014184 cornichon family AMPA receptor auxiliary protein 4 CNIH4 29097 NM_001277197 /// NM_001277198 /// NM_001277199 /// NM_001277200 /// NM_014184 /// NR_102347 /// XM_006711768 0035556 // intracellular signal transduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218729_at NM_020169 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020169.1 /DEF=Homo sapiens latexin protein (LXN), mRNA. /FEA=mRNA /GEN=LXN /PROD=latexin protein /DB_XREF=gi:9910395 /UG=Hs.109276 latexin protein /FL=gb:BC005346.1 gb:AF282626.1 gb:NM_020169.1 NM_020169 latexin LXN 56925 NM_020169 0006954 // inflammatory response // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 218730_s_at NM_014057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014057.1 /DEF=Homo sapiens osteoglycin (osteoinductive factor, mimecan) (OGN), mRNA. /FEA=mRNA /GEN=OGN /PROD=osteoglycin /DB_XREF=gi:7661703 /UG=Hs.109439 osteoglycin (osteoinductive factor, mimecan) /FL=gb:NM_024416.1 gb:AF100758.1 gb:AL110267.1 gb:NM_014057.1 gb:AF202167.1 NM_014057 osteoglycin OGN 4969 NM_014057 /// NM_024416 /// NM_033014 0005975 // carbohydrate metabolic process // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 218731_s_at NM_022834 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022834.1 /DEF=Homo sapiens hypothetical protein FLJ22215 (FLJ22215), mRNA. /FEA=mRNA /GEN=FLJ22215 /PROD=hypothetical protein FLJ22215 /DB_XREF=gi:12383079 /UG=Hs.110443 hypothetical protein FLJ22215 /FL=gb:NM_022834.1 gb:BC003543.1 NM_022834 von Willebrand factor A domain containing 1 VWA1 64856 NM_022834 /// NM_199121 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 218732_at NM_016077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016077.1 /DEF=Homo sapiens CGI-147 protein (LOC51651), mRNA. /FEA=mRNA /GEN=LOC51651 /PROD=CGI-147 protein /DB_XREF=gi:7706350 /UG=Hs.12677 CGI-147 protein /FL=gb:AF151905.1 gb:NM_016077.1 NM_016077 peptidyl-tRNA hydrolase 2 PTRH2 51651 NM_001015509 /// NM_016077 /// XM_005257447 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 2000210 // positive regulation of anoikis // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0016020 // membrane // inferred from direct assay 0004045 // aminoacyl-tRNA hydrolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 218733_at NM_018133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018133.1 /DEF=Homo sapiens hypothetical protein FLJ10546 (FLJ10546), mRNA. /FEA=mRNA /GEN=FLJ10546 /PROD=hypothetical protein FLJ10546 /DB_XREF=gi:8922505 /UG=Hs.129750 hypothetical protein FLJ10546 /FL=gb:NM_018133.1 NM_018133 male-specific lethal 2 homolog (Drosophila) MSL2 55167 NM_001145417 /// NM_018133 /// XM_005247571 /// XM_005247572 /// XM_006713684 0006325 // chromatin organization // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0005654 // nucleoplasm // traceable author statement /// 0072487 // MSL complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218734_at NM_024771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024771.1 /DEF=Homo sapiens hypothetical protein FLJ13848 (FLJ13848), mRNA. /FEA=mRNA /GEN=FLJ13848 /PROD=hypothetical protein FLJ13848 /DB_XREF=gi:13376118 /UG=Hs.136976 hypothetical protein FLJ13848 /FL=gb:NM_024771.1 NM_024771 N(alpha)-acetyltransferase 40, NatD catalytic subunit NAA40 79829 NM_024771 /// XM_005274295 /// XM_005274296 /// XM_006718689 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 218735_s_at AA349848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA349848 /FEA=EST /DB_XREF=gi:2002321 /DB_XREF=est:EST57002 /UG=Hs.142634 zinc finger protein /FL=gb:AF020591.1 gb:NM_014480.1 AA349848 zinc finger protein 544 ZNF544 27300 NM_014480 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 218736_s_at NM_017734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017734.1 /DEF=Homo sapiens hypothetical protein FLJ20271 (FLJ20271), mRNA. /FEA=mRNA /GEN=FLJ20271 /PROD=hypothetical protein FLJ20271 /DB_XREF=gi:8923242 /UG=Hs.14606 hypothetical protein FLJ20271 /FL=gb:NM_017734.1 NM_017734 palmdelphin PALMD 54873 NM_017734 0008360 // regulation of cell shape // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218737_at NM_018183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018183.1 /DEF=Homo sapiens hypothetical protein FLJ10701 (FLJ10701), mRNA. /FEA=mRNA /GEN=FLJ10701 /PROD=hypothetical protein FLJ10701 /DB_XREF=gi:8922598 /UG=Hs.146589 hypothetical protein FLJ10701 /FL=gb:AB014772.1 gb:NM_018183.1 NM_018183 strawberry notch homolog 1 (Drosophila) SBNO1 55206 NM_001167856 /// NM_018183 /// XM_005253572 /// XM_005253573 /// XM_005253575 /// XM_005253576 /// XM_006719473 /// XM_006719474 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218738_s_at NM_016271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016271.1 /DEF=Homo sapiens STRIN protein (STRIN), mRNA. /FEA=mRNA /GEN=STRIN /PROD=STRIN protein /DB_XREF=gi:7706722 /UG=Hs.180403 STRIN protein /FL=gb:AF162680.3 gb:NM_016271.1 NM_016271 ring finger protein 138, E3 ubiquitin protein ligase RNF138 51444 NM_001191324 /// NM_016271 /// NM_198128 /// XM_005258285 /// XM_005258286 /// XR_430075 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218739_at NM_016006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016006.1 /DEF=Homo sapiens CGI-58 protein (LOC51099), mRNA. /FEA=mRNA /GEN=LOC51099 /PROD=CGI-58 protein /DB_XREF=gi:7705770 /UG=Hs.19385 CGI-58 protein /FL=gb:AF151816.1 gb:NM_016006.1 NM_016006 abhydrolase domain containing 5 ABHD5 51099 NM_016006 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006654 // phosphatidic acid biosynthetic process // inferred from direct assay /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042171 // lysophosphatidic acid acyltransferase activity // inferred from direct assay 218740_s_at NM_025197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025197.1 /DEF=Homo sapiens hypothetical protein FLJ13660 similar to CDK5 activator-binding protein C53 (FLJ13660), mRNA. /FEA=mRNA /GEN=FLJ13660 /PROD=hypothetical protein FLJ13660 similar to CDK5activator-binding protein C53 /DB_XREF=gi:13376787 /UG=Hs.20157 hypothetical protein FLJ13660 similar to CDK5 activator-binding protein C53 /FL=gb:AF110322.1 gb:NM_025197.1 NM_025197 CDK5 regulatory subunit associated protein 3 CDK5RAP3 80279 NM_001278197 /// NM_001278198 /// NM_001278216 /// NM_001278217 /// NM_025197 /// NM_176095 /// NM_176096 /// XM_006722113 /// XM_006722114 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0007420 // brain development // non-traceable author statement /// 0045664 // regulation of neuron differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071569 // protein ufmylation // inferred from direct assay 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // non-traceable author statement 218741_at NM_024053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024053.1 /DEF=Homo sapiens hypothetical protein MGC861 (MGC861), mRNA. /FEA=mRNA /GEN=MGC861 /PROD=hypothetical protein MGC861 /DB_XREF=gi:13129021 /UG=Hs.208912 hypothetical protein MGC861 /FL=gb:BC000705.1 gb:NM_024053.1 NM_024053 centromere protein M CENPM 79019 NM_001002876 /// NM_001110215 /// NM_024053 /// XM_005261736 /// XR_244383 0000278 // mitotic cell cycle // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 218742_at NM_022493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022493.1 /DEF=Homo sapiens hypothetical protein FLJ21988 (FLJ21988), mRNA. /FEA=mRNA /GEN=FLJ21988 /PROD=hypothetical protein FLJ21988 /DB_XREF=gi:11968050 /UG=Hs.22158 hypothetical protein FLJ21988 /FL=gb:NM_022493.1 NM_022493 nuclear prelamin A recognition factor-like NARFL 64428 NM_022493 /// XM_005255500 0001666 // response to hypoxia // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0016226 // iron-sulfur cluster assembly // inferred from mutant phenotype /// 0032364 // oxygen homeostasis // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0097361 // CIA complex // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 218743_at NM_024591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024591.1 /DEF=Homo sapiens hypothetical protein FLJ11749 (FLJ11749), mRNA. /FEA=mRNA /GEN=FLJ11749 /PROD=hypothetical protein FLJ11749 /DB_XREF=gi:13375782 /UG=Hs.22897 hypothetical protein FLJ11749 /FL=gb:NM_024591.1 NM_024591 charged multivesicular body protein 6 CHMP6 79643 NM_024591 /// XM_005257668 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 218744_s_at NM_016223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016223.1 /DEF=Homo sapiens SH3 domain-containing protein 6511 (LOC51165), mRNA. /FEA=mRNA /GEN=LOC51165 /PROD=SH3 domain-containing protein 6511 /DB_XREF=gi:7705894 /UG=Hs.256310 protein kinase C and casein kinase substrate in neurons 3 /FL=gb:AF149825.1 gb:AF130979.1 gb:NM_016223.1 NM_016223 protein kinase C and casein kinase substrate in neurons 3 PACSIN3 29763 NM_001184974 /// NM_001184975 /// NM_016223 0006897 // endocytosis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051926 // negative regulation of calcium ion transport // inferred from sequence or structural similarity /// 0097320 // membrane tubulation // inferred from direct assay 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from sequence or structural similarity 218745_x_at NM_017814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017814.1 /DEF=Homo sapiens hypothetical protein FLJ20422 (FLJ20422), mRNA. /FEA=mRNA /GEN=FLJ20422 /PROD=hypothetical protein FLJ20422 /DB_XREF=gi:8923393 /UG=Hs.26570 hypothetical protein FLJ20422 /FL=gb:BC005210.1 gb:NM_017814.1 NM_017814 transmembrane protein 161A TMEM161A 54929 NM_001256766 /// NM_017814 /// XM_005259976 0032526 // response to retinoic acid // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218746_at NM_018009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018009.1 /DEF=Homo sapiens hypothetical protein FLJ10143 (FLJ10143), mRNA. /FEA=mRNA /GEN=FLJ10143 /PROD=hypothetical protein FLJ10143 /DB_XREF=gi:8922253 /UG=Hs.267993 hypothetical protein FLJ10143 /FL=gb:NM_018009.1 NM_018009 TAP binding protein-like TAPBPL 55080 NM_018009 /// XM_005253699 /// XM_005253700 /// XM_005253701 /// XM_005253702 /// XM_005253703 /// XR_429016 0002590 // negative regulation of antigen processing and presentation of peptide antigen via MHC class I // inferred from direct assay /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from physical interaction 218747_s_at NM_018009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018009.1 /DEF=Homo sapiens hypothetical protein FLJ10143 (FLJ10143), mRNA. /FEA=mRNA /GEN=FLJ10143 /PROD=hypothetical protein FLJ10143 /DB_XREF=gi:8922253 /UG=Hs.267993 hypothetical protein FLJ10143 /FL=gb:NM_018009.1 NM_018009 TAP binding protein-like TAPBPL 55080 NM_018009 /// XM_005253699 /// XM_005253700 /// XM_005253701 /// XM_005253702 /// XM_005253703 /// XR_429016 0002590 // negative regulation of antigen processing and presentation of peptide antigen via MHC class I // inferred from direct assay /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from physical interaction 218748_s_at NM_006544 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006544.1 /DEF=Homo sapiens SEC10 (S. cerevisiae)-like 1 (SEC10L1), mRNA. /FEA=mRNA /GEN=SEC10L1 /PROD=SEC10 (S. cerevisiae)-like 1 /DB_XREF=gi:5730036 /UG=Hs.279947 SEC10 (S. cerevisiae)-like 1 /FL=gb:U85946.1 gb:NM_006544.1 NM_006544 exocyst complex component 5 EXOC5 10640 NM_006544 /// XM_005267272 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048278 // vesicle docking // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0047485 // protein N-terminus binding // inferred from electronic annotation 218749_s_at NM_024959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024959.1 /DEF=Homo sapiens hypothetical protein FLJ22233 (FLJ22233), mRNA. /FEA=mRNA /GEN=FLJ22233 /PROD=hypothetical protein FLJ22233 /DB_XREF=gi:13376448 /UG=Hs.286194 hypothetical protein FLJ22233 /FL=gb:NM_024959.1 NM_024959 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 SLC8B1 80024 NM_024959 /// XM_006719607 /// XM_006719608 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006851 // mitochondrial calcium ion transport // inferred from direct assay /// 0006851 // mitochondrial calcium ion transport // inferred from mutant phenotype /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation 0005432 // calcium:sodium antiporter activity // inferred from direct assay /// 0015297 // antiporter activity // inferred from electronic annotation 218750_at NM_024116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024116.1 /DEF=Homo sapiens hypothetical protein MGC5306 (MGC5306), mRNA. /FEA=mRNA /GEN=MGC5306 /PROD=hypothetical protein MGC5306 /DB_XREF=gi:13129135 /UG=Hs.301732 hypothetical protein MGC5306 /FL=gb:AF275800.1 gb:NM_024116.1 NM_024116 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa TAF1D 79101 NM_024116 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005668 // RNA polymerase transcription factor SL1 complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218751_s_at NM_018315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018315.1 /DEF=Homo sapiens hypothetical protein FLJ11071 (FLJ11071), mRNA. /FEA=mRNA /GEN=FLJ11071 /PROD=hypothetical protein FLJ11071 /DB_XREF=gi:8922851 /UG=Hs.31945 hypothetical protein FLJ11071 /FL=gb:NM_018315.1 NM_018315 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase FBXW7 55294 NM_001013415 /// NM_001257069 /// NM_018315 /// NM_033632 0001570 // vasculogenesis // inferred from electronic annotation /// 0001944 // vasculature development // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0010868 // negative regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010883 // regulation of lipid storage // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from direct assay /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000346 // negative regulation of hepatocyte proliferation // inferred from sequence or structural similarity /// 2000639 // negative regulation of SREBP signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218752_at NM_019103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019103.1 /DEF=Homo sapiens hypothetical protein (LOC55954), mRNA. /FEA=mRNA /GEN=LOC55954 /PROD=hypothetical protein /DB_XREF=gi:9506862 /UG=Hs.38628 hypothetical protein /FL=gb:NM_019103.1 NM_019103 zinc finger, matrin-type 5 ZMAT5 55954 NM_001003692 /// NM_019103 /// XM_005261683 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218753_at NM_018053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018053.1 /DEF=Homo sapiens hypothetical protein FLJ10307 (FLJ10307), mRNA. /FEA=mRNA /GEN=FLJ10307 /PROD=hypothetical protein FLJ10307 /DB_XREF=gi:8922341 /UG=Hs.55024 hypothetical protein FLJ10307 /FL=gb:BC003606.1 gb:NM_018053.1 NM_018053 XK, Kell blood group complex subunit-related family, member 8 XKR8 55113 NM_018053 0006915 // apoptotic process // inferred from electronic annotation /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0070782 // phosphatidylserine exposure on apoptotic cell surface // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218754_at NM_024654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024654.1 /DEF=Homo sapiens hypothetical protein FLJ23323 (FLJ23323), mRNA. /FEA=mRNA /GEN=FLJ23323 /PROD=hypothetical protein FLJ23323 /DB_XREF=gi:13375902 /UG=Hs.59425 hypothetical protein FLJ23323 /FL=gb:NM_024654.1 NM_024654 nucleolar protein 9 NOL9 79707 NM_024654 /// XM_005263493 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0051731 // polynucleotide 5'-hydroxyl-kinase activity // inferred from direct assay 218755_at NM_005733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005733.1 /DEF=Homo sapiens RAB6 interacting, kinesin-like (rabkinesin6) (RAB6KIFL), mRNA. /FEA=mRNA /GEN=RAB6KIFL /PROD=RAB6 interacting, kinesin-like (rabkinesin6) /DB_XREF=gi:5032012 /UG=Hs.73625 RAB6 interacting, kinesin-like (rabkinesin6) /FL=gb:AF070672.1 gb:AF153329.1 gb:NM_005733.1 NM_005733 kinesin family member 20A KIF20A 10112 NM_005733 /// XM_006714514 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from direct assay /// 0001578 // microtubule bundle formation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 218756_s_at NM_024308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024308.1 /DEF=Homo sapiens hypothetical protein MGC4172 (MGC4172), mRNA. /FEA=mRNA /GEN=MGC4172 /PROD=hypothetical protein MGC4172 /DB_XREF=gi:13236541 /UG=Hs.8949 hypothetical protein MGC4172 /FL=gb:BC002731.1 gb:NM_024308.1 NM_024308 dehydrogenase/reductase (SDR family) member 11 DHRS11 79154 NM_024308 /// XM_005257658 /// XM_006722077 /// XM_006722078 /// XM_006725346 /// XM_006725347 /// XM_006725348 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 218757_s_at NM_023010 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023010.1 /DEF=Homo sapiens similar to yeast Upf3, variant B (UPF3B), mRNA. /FEA=mRNA /GEN=UPF3B /PROD=similar to yeast Upf3, variant B /DB_XREF=gi:12711673 /UG=Hs.103832 similar to yeast Upf3, variant B /FL=gb:AY013251.1 gb:NM_023010.1 NM_023010 UPF3 regulator of nonsense transcripts homolog B (yeast) UPF3B 65109 NM_023010 /// NM_080632 /// XM_005262458 /// XM_006724780 /// XM_006724781 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // non-traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218758_s_at NM_003683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003683.1 /DEF=Homo sapiens DNA segment on chromosome 21 (unique) 2056 expressed sequence (D21S2056E), mRNA. /FEA=mRNA /GEN=D21S2056E /PROD=NNP-1Nop52, novel nuclear protein 1 /DB_XREF=gi:4503246 /UG=Hs.110757 DNA segment on chromosome 21 (unique) 2056 expressed sequence /FL=gb:BC000380.1 gb:U79775.1 gb:NM_003683.1 NM_003683 ribosomal RNA processing 1 RRP1 8568 NM_003683 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030688 // preribosome, small subunit precursor // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 218759_at NM_004422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004422.1 /DEF=Homo sapiens dishevelled 2 (homologous to Drosophila dsh) (DVL2), mRNA. /FEA=mRNA /GEN=DVL2 /PROD=dishevelled 2 /DB_XREF=gi:4758215 /UG=Hs.118640 dishevelled 2 (homologous to Drosophila dsh) /FL=gb:AF006012.1 gb:NM_004422.1 NM_004422 dishevelled segment polarity protein 2 DVL2 1856 NM_004422 /// XM_005256502 /// XM_006721469 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // not recorded /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from genetic interaction /// 0021535 // cell migration in hindbrain // not recorded /// 0022007 // convergent extension involved in neural plate elongation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035282 // segmentation // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0044340 // canonical Wnt signaling pathway involved in regulation of cell proliferation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005938 // cell cortex // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // not recorded /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045177 // apical part of cell // not recorded /// 0045334 // clathrin-coated endocytic vesicle // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from electronic annotation 218760_at NM_015940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015940.1 /DEF=Homo sapiens CGI-10 protein (LOC51004), mRNA. /FEA=mRNA /GEN=LOC51004 /PROD=CGI-10 protein /DB_XREF=gi:7705593 /UG=Hs.12239 CGI-10 protein /FL=gb:AF132944.1 gb:NM_015940.1 NM_015940 coenzyme Q6 monooxygenase COQ6 51004 NM_182476 /// NM_182480 /// XM_005267716 /// XM_005267718 /// XM_005267719 /// XM_005267720 /// XM_006720156 /// XR_429317 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 218761_at NM_017610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017610.1 /DEF=Homo sapiens hypothetical protein DKFZp761D081 (DKFZp761D081), mRNA. /FEA=mRNA /GEN=DKFZp761D081 /PROD=hypothetical protein DKFZp761D081 /DB_XREF=gi:8922164 /UG=Hs.12504 hypothetical protein DKFZp761D081 /FL=gb:NM_017610.1 NM_017610 ring finger protein 111 RNF111 54778 NM_001270528 /// NM_001270529 /// NM_001270530 /// NM_017610 /// XM_005254473 /// XM_005254475 /// XM_005254476 /// XM_005254479 /// XM_006720575 /// XM_006720576 /// XM_006720577 /// XM_006720578 /// XM_006720579 /// XM_006720580 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030579 // ubiquitin-dependent SMAD protein catabolic process // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0032184 // SUMO polymer binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218762_at NM_022752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022752.1 /DEF=Homo sapiens hypothetical protein FLJ22059 (FLJ22059), mRNA. /FEA=mRNA /GEN=FLJ22059 /PROD=hypothetical protein FLJ22059 /DB_XREF=gi:12232416 /UG=Hs.13323 hypothetical protein FLJ22059 /FL=gb:NM_022752.1 gb:BC001184.1 NM_022752 zinc finger protein 574 ZNF574 64763 NM_022752 /// XM_005259159 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218763_at NM_016930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016930.1 /DEF=Homo sapiens syntaxin 18 (STX18), mRNA. /FEA=mRNA /GEN=STX18 /PROD=syntaxin 18 /DB_XREF=gi:8394375 /UG=Hs.13406 syntaxin 18 /FL=gb:AB028741.1 gb:NM_016930.1 NM_016930 syntaxin 18 STX18 53407 NM_016930 /// XM_005247972 /// XM_005247973 /// XR_241651 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218764_at NM_024064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024064.1 /DEF=Homo sapiens hypothetical protein MGC5363 (MGC5363), mRNA. /FEA=mRNA /GEN=MGC5363 /PROD=hypothetical protein MGC5363 /DB_XREF=gi:13129041 /UG=Hs.1880 hypothetical protein MGC5363 /FL=gb:BC001000.2 gb:NM_024064.1 NM_024064 protein kinase C, eta PRKCH 5583 NM_006255 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from sequence or structural similarity /// 0050861 // positive regulation of B cell receptor signaling pathway // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0060252 // positive regulation of glial cell proliferation // inferred from mutant phenotype /// 0070528 // protein kinase C signaling // inferred from electronic annotation /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004697 // protein kinase C activity // traceable author statement /// 0004699 // calcium-independent protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017160 // Ral GTPase binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218765_at NM_015996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015996.1 /DEF=Homo sapiens CGI-40 protein (LOC51092), mRNA. /FEA=mRNA /GEN=LOC51092 /PROD=CGI-40 protein /DB_XREF=gi:7705756 /UG=Hs.20102 CGI-40 protein /FL=gb:AF151799.1 gb:NM_015996.1 NM_015996 SID1 transmembrane family, member 2 SIDT2 51092 NM_001040455 /// NM_015996 0033227 // dsRNA transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0051033 // RNA transmembrane transporter activity // inferred from electronic annotation 218766_s_at NM_015836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015836.1 /DEF=Homo sapiens tryptophanyl tRNA synthetase 2 (mitochondrial) (WARS2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=WARS2 /PROD=tryptophanyl tRNA synthetase 2 (mitochondrial) /DB_XREF=gi:7710153 /UG=Hs.227274 tryptophanyl tRNA synthetase 2 (mitochondrial) /FL=gb:NM_015836.1 NM_015836 tryptophanyl tRNA synthetase 2, mitochondrial WARS2 10352 NM_015836 /// NM_201263 /// XM_005270350 /// XM_005270352 /// XM_006710283 /// XM_006710284 0001570 // vasculogenesis // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 218767_at NM_020385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020385.1 /DEF=Homo sapiens XPMC2 protein (LOC57109), mRNA. /FEA=mRNA /GEN=LOC57109 /PROD=XPMC2 protein /DB_XREF=gi:9966856 /UG=Hs.235376 XPMC2 protein /FL=gb:AL136894.1 gb:AF273304.1 gb:AF295774.1 gb:NM_020385.1 NM_020385 REX4, RNA exonuclease 4 homolog (S. cerevisiae) REXO4 57109 NM_001279349 /// NM_001279350 /// NM_001279351 /// NM_020385 /// NR_103995 /// NR_103996 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218768_at NM_020401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020401.1 /DEF=Homo sapiens nuclear pore complex protein (NUP107), mRNA. /FEA=mRNA /GEN=NUP107 /PROD=nuclear pore complex protein /DB_XREF=gi:9966880 /UG=Hs.236204 nuclear pore complex protein /FL=gb:NM_020401.1 NM_020401 nucleoporin 107kDa NUP107 57122 NM_020401 /// XM_005269037 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 218769_s_at NM_023039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023039.1 /DEF=Homo sapiens ankyrin repeat, family A (RFXANK-like), 2 (ANKRA2), mRNA. /FEA=mRNA /GEN=ANKRA2 /PROD=ankyrin repeat, family A (RFXANK-like), 2 /DB_XREF=gi:12746411 /UG=Hs.239154 ankyrin repeat, family A (RFXANK-like), 2 /FL=gb:AF314032.1 gb:NM_023039.1 NM_023039 ankyrin repeat, family A (RFXANK-like), 2 ANKRA2 57763 NM_023039 /// XM_005248560 /// XR_241786 /// XR_241787 /// XR_427716 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from electronic annotation 218770_s_at NM_018056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018056.1 /DEF=Homo sapiens hypothetical protein FLJ10315 (FLJ10315), mRNA. /FEA=mRNA /GEN=FLJ10315 /PROD=hypothetical protein FLJ10315 /DB_XREF=gi:8922347 /UG=Hs.25544 hypothetical protein FLJ10315 /FL=gb:AL136695.1 gb:NM_018056.1 NM_018056 transmembrane protein 39B TMEM39B 55116 NM_018056 /// XM_005270988 /// XM_005270989 /// XM_006710724 /// XM_006710725 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218771_at NM_018216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018216.1 /DEF=Homo sapiens hypothetical protein FLJ10782 (FLJ10782), mRNA. /FEA=mRNA /GEN=FLJ10782 /PROD=hypothetical protein FLJ10782 /DB_XREF=gi:8922664 /UG=Hs.26156 hypothetical protein FLJ10782 /FL=gb:NM_018216.1 NM_018216 pantothenate kinase 4 PANK4 55229 NM_018216 /// XR_241034 /// XR_430631 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004594 // pantothenate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218772_x_at NM_018112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018112.1 /DEF=Homo sapiens hypothetical protein FLJ10493 (FLJ10493), mRNA. /FEA=mRNA /GEN=FLJ10493 /PROD=hypothetical protein FLJ10493 /DB_XREF=gi:8922460 /UG=Hs.279610 hypothetical protein FLJ10493 /FL=gb:BC000049.1 gb:NM_018112.1 NM_018112 transmembrane protein 38B TMEM38B 55151 NM_018112 /// XM_005252075 /// XM_005252076 /// XM_005252077 /// XM_005252078 /// XR_428531 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // non-traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // non-traceable author statement 0005261 // cation channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // traceable author statement 218773_s_at NM_012228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012228.1 /DEF=Homo sapiens pilin-like transcription factor (PILB), mRNA. /FEA=mRNA /GEN=PILB /PROD=pilin-like transcription factor /DB_XREF=gi:6912591 /UG=Hs.279754 pilin-like transcription factor /FL=gb:AF122004.1 gb:NM_012228.1 NM_012228 methionine sulfoxide reductase B2 MSRB2 22921 NM_012228 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030091 // protein repair // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0033743 // peptide-methionine (R)-S-oxide reductase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 218774_at NM_014026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014026.1 /DEF=Homo sapiens HSPC015 protein (HSPC015), mRNA. /FEA=mRNA /GEN=HSPC015 /PROD=HSPC015 protein /DB_XREF=gi:7661733 /UG=Hs.279900 HSPC015 protein /FL=gb:AF077201.1 gb:NM_014026.1 NM_014026 decapping enzyme, scavenger DCPS 28960 NM_014026 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000290 // deadenylation-dependent decapping of nuclear-transcribed mRNA // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0036245 // cellular response to menadione // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050072 // m7G(5')pppN diphosphatase activity // inferred from direct assay 218775_s_at NM_024949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024949.1 /DEF=Homo sapiens hypothetical protein FLJ22029 (FLJ22029), mRNA. /FEA=mRNA /GEN=FLJ22029 /PROD=hypothetical protein FLJ22029 /DB_XREF=gi:13376432 /UG=Hs.285243 hypothetical protein FLJ22029 /FL=gb:NM_024949.1 NM_024949 claudin 22 /// WW and C2 domain containing 2 CLDN22 /// WWC2 53842 /// 80014 NM_001111319 /// NM_024949 /// XM_006714312 /// XM_006714313 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0045216 // cell-cell junction organization // traceable author statement /// 0046621 // negative regulation of organ growth // inferred from mutant phenotype /// 0070830 // tight junction assembly // traceable author statement 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay /// 0042802 // identical protein binding // inferred from sequence or structural similarity 218776_s_at NM_024956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024956.1 /DEF=Homo sapiens hypothetical protein FLJ23375 (FLJ23375), mRNA. /FEA=mRNA /GEN=FLJ23375 /PROD=hypothetical protein FLJ23375 /DB_XREF=gi:13376442 /UG=Hs.285996 hypothetical protein FLJ23375 /FL=gb:NM_024956.1 NM_024956 transmembrane protein 62 TMEM62 80021 NM_024956 /// XM_005254682 /// XM_005254683 /// XM_005254684 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 218777_at NM_025232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025232.1 /DEF=Homo sapiens hypothetical protein FLJ22246 (FLJ22246), mRNA. /FEA=mRNA /GEN=FLJ22246 /PROD=hypothetical protein FLJ22246 /DB_XREF=gi:13376835 /UG=Hs.289063 hypothetical protein FLJ22246 /FL=gb:NM_025232.1 NM_025232 receptor accessory protein 4 REEP4 80346 NM_025232 /// XM_006716403 0006998 // nuclear envelope organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007084 // mitotic nuclear envelope reassembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008017 // microtubule binding // inferred from sequence or structural similarity 218778_x_at AI343292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI343292 /FEA=EST /DB_XREF=gi:4080498 /DB_XREF=est:tb94e09.x1 /CLONE=IMAGE:2062024 /UG=Hs.28907 hypothetical protein FLJ20258 /FL=gb:NM_017729.1 AI343292 EPS8-like 1 EPS8L1 54869 NM_017729 /// NM_133180 /// NM_139204 /// XM_005259020 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from physical interaction 218779_x_at NM_017729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017729.1 /DEF=Homo sapiens hypothetical protein FLJ20258 (FLJ20258), mRNA. /FEA=mRNA /GEN=FLJ20258 /PROD=hypothetical protein FLJ20258 /DB_XREF=gi:8923231 /UG=Hs.28907 hypothetical protein FLJ20258 /FL=gb:NM_017729.1 NM_017729 EPS8-like 1 EPS8L1 54869 NM_017729 /// NM_133180 /// NM_139204 /// XM_005259020 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from physical interaction 218780_at NM_013312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013312.1 /DEF=Homo sapiens hook2 protein (HOOK2), mRNA. /FEA=mRNA /GEN=HOOK2 /PROD=hook2 protein /DB_XREF=gi:7019410 /UG=Hs.30792 hook2 protein /FL=gb:AF044924.1 gb:NM_013312.1 NM_013312 hook microtubule-tethering protein 2 HOOK2 29911 NM_001100176 /// NM_013312 /// XM_005259873 /// XM_005259874 /// XM_005259876 /// XM_005259877 /// XM_005259878 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0070695 // FHF complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 218781_at NM_024624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024624.1 /DEF=Homo sapiens hypothetical protein FLJ22116 (FLJ22116), mRNA. /FEA=mRNA /GEN=FLJ22116 /PROD=hypothetical protein FLJ22116 /DB_XREF=gi:13375847 /UG=Hs.34497 hypothetical protein FLJ22116 /FL=gb:AL136544.1 gb:NM_024624.1 NM_024624 structural maintenance of chromosomes 6 SMC6 79677 NM_001142286 /// NM_024624 /// XM_005262628 /// XM_006712103 0000722 // telomere maintenance via recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030915 // Smc5-Smc6 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 218782_s_at NM_014109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014109.1 /DEF=Homo sapiens PRO2000 protein (PRO2000), mRNA. /FEA=mRNA /GEN=PRO2000 /PROD=PRO2000 protein /DB_XREF=gi:7662630 /UG=Hs.46677 PRO2000 protein /FL=gb:AF118088.1 gb:NM_014109.1 NM_014109 ATPase family, AAA domain containing 2 ATAD2 29028 NM_014109 0006200 // ATP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 218783_at AL133049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL133049.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E1315 (from clone DKFZp434E1315); complete cds. /FEA=mRNA /GEN=DKFZp434E1315 /PROD=hypothetical protein /DB_XREF=gi:6453464 /UG=Hs.48604 DKFZP434B168 protein /FL=gb:AL133049.1 gb:NM_015434.1 AL133049 integrator complex subunit 7 INTS7 25896 NM_001199809 /// NM_001199811 /// NM_001199812 /// NM_015434 /// NR_037667 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218784_s_at NM_018322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018322.1 /DEF=Homo sapiens hypothetical protein FLJ11101 (FLJ11101), mRNA. /FEA=mRNA /GEN=FLJ11101 /PROD=hypothetical protein FLJ11101 /DB_XREF=gi:8922866 /UG=Hs.58382 hypothetical protein FLJ11101 /FL=gb:NM_018322.1 NM_018322 SAYSVFN motif domain containing 1 SAYSD1 55776 NM_018322 /// XM_005249222 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 218785_s_at NM_022777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022777.1 /DEF=Homo sapiens hypothetical protein FLJ14117 (FLJ14117), mRNA. /FEA=mRNA /GEN=FLJ14117 /PROD=hypothetical protein FLJ14117 /DB_XREF=gi:12232462 /UG=Hs.61809 hypothetical protein FLJ14117 /FL=gb:NM_022777.1 NM_022777 intraflagellar transport 22 homolog (Chlamydomonas) IFT22 64792 NM_001130820 /// NM_001130821 /// NM_001130822 /// NM_001287525 /// NM_001287526 /// NM_022777 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218786_at NM_016575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016575.1 /DEF=Homo sapiens TU12B1-TY protein (TU12B1-TY), mRNA. /FEA=mRNA /GEN=TU12B1-TY /PROD=TU12B1-TY protein /DB_XREF=gi:7706748 /UG=Hs.6341 TU12B1-TY protein /FL=gb:AB032773.1 gb:NM_016575.1 NM_016575 5'-nucleotidase domain containing 3 NT5DC3 51559 NM_001031701 /// NM_016575 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218787_x_at NM_018294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018294.1 /DEF=Homo sapiens hypothetical protein FLJ10998 (FLJ10998), mRNA. /FEA=mRNA /GEN=FLJ10998 /PROD=hypothetical protein FLJ10998 /DB_XREF=gi:8922811 /UG=Hs.78110 hypothetical protein FLJ10998 /FL=gb:NM_018294.1 NM_018294 CWF19-like 1, cell cycle control (S. pombe) CWF19L1 55280 NM_018294 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation 218788_s_at NM_022743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022743.1 /DEF=Homo sapiens hypothetical protein FLJ21080 (FLJ21080), mRNA. /FEA=mRNA /GEN=FLJ21080 /PROD=hypothetical protein FLJ21080 /DB_XREF=gi:12232400 /UG=Hs.8109 hypothetical protein FLJ21080 /FL=gb:NM_022743.1 NM_022743 SET and MYND domain containing 3 SMYD3 64754 NM_001167740 /// NM_022743 /// XM_005273228 /// XM_005273229 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 218789_s_at NM_019021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019021.1 /DEF=Homo sapiens hypothetical protein (FLJ20010), mRNA. /FEA=mRNA /GEN=FLJ20010 /PROD=hypothetical protein /DB_XREF=gi:9506646 /UG=Hs.91816 hypothetical protein /FL=gb:NM_019021.1 NM_019021 chromosome 11 open reading frame 71 C11orf71 54494 NM_001271562 /// NM_019021 218790_s_at NM_018196 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018196.1 /DEF=Homo sapiens hypothetical protein FLJ10727 (FLJ10727), mRNA. /FEA=mRNA /GEN=FLJ10727 /PROD=hypothetical protein FLJ10727 /DB_XREF=gi:8922624 /UG=Hs.103816 hypothetical protein FLJ10727 /FL=gb:NM_018196.1 NM_018196 trimethyllysine hydroxylase, epsilon TMLHE 55217 NM_001184797 /// NM_018196 /// XR_247318 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from direct assay /// 0045329 // carnitine biosynthetic process // inferred from electronic annotation /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0051354 // negative regulation of oxidoreductase activity // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050353 // trimethyllysine dioxygenase activity // inferred from direct assay /// 0050353 // trimethyllysine dioxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 218791_s_at NM_024713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024713.1 /DEF=Homo sapiens hypothetical protein FLJ22557 (FLJ22557), mRNA. /FEA=mRNA /GEN=FLJ22557 /PROD=hypothetical protein FLJ22557 /DB_XREF=gi:13376012 /UG=Hs.106101 hypothetical protein FLJ22557 /FL=gb:AL136908.1 gb:NM_024713.1 NM_024713 katanin p80 subunit B-like 1 KATNBL1 79768 NM_024713 /// XM_005254666 /// XM_005254667 /// XM_005254668 /// XM_006720684 0005730 // nucleolus // inferred from direct assay 218792_s_at NM_017688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017688.1 /DEF=Homo sapiens hypothetical protein FLJ20150 (FLJ20150), mRNA. /FEA=mRNA /GEN=FLJ20150 /PROD=hypothetical protein FLJ20150 /DB_XREF=gi:8923147 /UG=Hs.108502 hypothetical protein FLJ20150 /FL=gb:NM_017688.1 NM_017688 B-box and SPRY domain containing BSPRY 54836 NM_017688 /// XM_005252062 /// XM_005252063 /// XM_006717149 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218793_s_at NM_006746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006746.1 /DEF=Homo sapiens sex comb on midleg (Drosophila)-like 1 (SCML1), mRNA. /FEA=mRNA /GEN=SCML1 /PROD=sex comb on midleg (Drosophila)-like 1 /DB_XREF=gi:5803158 /UG=Hs.109655 sex comb on midleg (Drosophila)-like 1 /FL=gb:AF160728.1 gb:NM_006746.1 NM_006746 sex comb on midleg-like 1 (Drosophila) SCML1 6322 NM_001037535 /// NM_001037536 /// NM_001037540 /// NM_006746 /// XM_005274578 /// XM_005274579 /// XM_006724508 /// XM_006724509 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 218794_s_at NM_017853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017853.1 /DEF=Homo sapiens hypothetical protein FLJ20511 (FLJ20511), mRNA. /FEA=mRNA /GEN=FLJ20511 /PROD=hypothetical protein FLJ20511 /DB_XREF=gi:8923474 /UG=Hs.134406 hypothetical protein FLJ20511 /FL=gb:NM_017853.1 NM_017853 thioredoxin-like 4B TXNL4B 54957 NM_001142317 /// NM_001142318 /// NM_017853 /// XM_006721212 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation 218795_at NM_016361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016361.1 /DEF=Homo sapiens LPAP for lysophosphatidic acid phosphatase (LOC51205), mRNA. /FEA=mRNA /GEN=LOC51205 /PROD=LPAP for lysophosphatidic acid phosphatase /DB_XREF=gi:7705954 /UG=Hs.15871 LPAP for lysophosphatidic acid phosphatase /FL=gb:AB031478.1 gb:AB030039.2 gb:NM_016361.1 NM_016361 acid phosphatase 6, lysophosphatidic ACP6 51205 NM_016361 /// XM_005277400 /// XM_006711363 /// XM_006711364 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 2001311 // lysobisphosphatidic acid metabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0052642 // lysophosphatidic acid phosphatase activity // inferred from direct assay 218796_at NM_017671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017671.1 /DEF=Homo sapiens hypothetical protein FLJ20116 (FLJ20116), mRNA. /FEA=mRNA /GEN=FLJ20116 /PROD=hypothetical protein FLJ20116 /DB_XREF=gi:8923115 /UG=Hs.180479 hypothetical protein FLJ20116 /FL=gb:NM_017671.1 NM_017671 fermitin family member 1 FERMT1 55612 NM_017671 0007155 // cell adhesion // inferred from direct assay /// 0043616 // keratinocyte proliferation // inferred from direct assay /// 0051546 // keratinocyte migration // inferred from direct assay /// 0090162 // establishment of epithelial cell polarity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 218797_s_at NM_016538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016538.1 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7 (SIRT7), mRNA. /FEA=mRNA /GEN=SIRT7 /PROD=sirtuin 7 /DB_XREF=gi:7706711 /UG=Hs.184447 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7 /FL=gb:AF233395.1 gb:NM_016538.1 NM_016538 sirtuin 7 SIRT7 51547 NM_016538 /// XM_005256376 /// XM_006722283 /// XM_006722284 /// XR_430032 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007072 // positive regulation of transcription on exit from mitosis // inferred from mutant phenotype /// 0009303 // rRNA transcription // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005731 // nucleolus organizer region // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from direct assay 218798_at NM_023008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023008.1 /DEF=Homo sapiens hypothetical protein FLJ12949 (FLJ12949), mRNA. /FEA=mRNA /GEN=FLJ12949 /PROD=hypothetical protein FLJ12949 /DB_XREF=gi:12711671 /UG=Hs.184519 hypothetical protein FLJ12949 /FL=gb:NM_023008.1 gb:BC002890.1 NM_023008 KRI1 homolog (S. cerevisiae) KRI1 65095 NM_023008 /// NM_178159 0005730 // nucleolus // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 218799_at NM_018066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018066.1 /DEF=Homo sapiens hypothetical protein FLJ10349 (FLJ10349), mRNA. /FEA=mRNA /GEN=FLJ10349 /PROD=hypothetical protein FLJ10349 /DB_XREF=gi:8922365 /UG=Hs.19333 hypothetical protein FLJ10349 /FL=gb:NM_018066.1 NM_018066 GPN-loop GTPase 2 GPN2 54707 NM_018066 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218800_at NM_024592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024592.1 /DEF=Homo sapiens hypothetical protein FLJ13352 (FLJ13352), mRNA. /FEA=mRNA /GEN=FLJ13352 /PROD=hypothetical protein FLJ13352 /DB_XREF=gi:13375784 /UG=Hs.22972 hypothetical protein FLJ13352 /FL=gb:BC002480.1 gb:NM_024592.1 NM_024592 steroid 5 alpha-reductase 3 SRD5A3 79644 NM_024592 /// XM_005265766 /// XM_005265767 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // inferred from mutant phenotype /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0016095 // polyprenol catabolic process // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019348 // dolichol metabolic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003865 // 3-oxo-5-alpha-steroid 4-dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from direct assay /// 0047751 // cholestenone 5-alpha-reductase activity // inferred from electronic annotation 218801_at NM_020121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020121.2 /DEF=Homo sapiens UDP-glucose:glycoprotein glucosyltransferase 2 (FLJ10873), mRNA. /FEA=mRNA /GEN=FLJ10873 /PROD=UDP-glucose:glycoprotein glucosyltransferase 2 /DB_XREF=gi:11386200 /UG=Hs.22983 UDP-glucose:glycoprotein glucosyltransferase 2 /FL=gb:AF227906.2 gb:NM_020121.2 NM_020121 UDP-glucose glycoprotein glucosyltransferase 2 UGGT2 55757 NM_020121 0006457 // protein folding // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097359 // UDP-glucosylation // inferred from electronic annotation /// 0097359 // UDP-glucosylation // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation 0003980 // UDP-glucose:glycoprotein glucosyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 218802_at NM_017918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017918.1 /DEF=Homo sapiens hypothetical protein FLJ20647 (FLJ20647), mRNA. /FEA=mRNA /GEN=FLJ20647 /PROD=hypothetical protein FLJ20647 /DB_XREF=gi:8923601 /UG=Hs.234149 hypothetical protein FLJ20647 /FL=gb:BC002633.1 gb:NM_017918.1 NM_017918 coiled-coil domain containing 109B CCDC109B 55013 NM_017918 /// XM_006714246 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006851 // mitochondrial calcium ion transport // inferred from sequence or structural similarity /// 0051560 // mitochondrial calcium ion homeostasis // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from sequence or structural similarity /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay /// 0034704 // calcium channel complex // inferred from sequence or structural similarity /// 1990246 // uniplex complex // inferred from direct assay 0005216 // ion channel activity // inferred from sequence or structural similarity /// 0019855 // calcium channel inhibitor activity // inferred from sequence or structural similarity 218803_at NM_018223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018223.1 /DEF=Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), mRNA. /FEA=mRNA /GEN=CHFR /PROD=checkpoint with forkhead and ring fingerdomains /DB_XREF=gi:8922674 /UG=Hs.23794 checkpoint with forkhead and ring finger domains /FL=gb:NM_018223.1 NM_018223 checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase CHFR 55743 NM_001161344 /// NM_001161345 /// NM_001161346 /// NM_001161347 /// NM_018223 0000209 // protein polyubiquitination // inferred from direct assay /// 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019941 // modification-dependent protein catabolic process // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218804_at NM_018043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018043.1 /DEF=Homo sapiens hypothetical protein FLJ10261 (FLJ10261), mRNA. /FEA=mRNA /GEN=FLJ10261 /PROD=hypothetical protein FLJ10261 /DB_XREF=gi:8922319 /UG=Hs.26176 hypothetical protein FLJ10261 /FL=gb:NM_018043.1 NM_018043 anoctamin 1, calcium activated chloride channel ANO1 55107 NM_018043 /// NR_030691 /// XM_006718593 /// XM_006718594 /// XM_006718595 /// XM_006718596 /// XM_006718597 /// XM_006718598 /// XM_006718599 /// XM_006718600 /// XM_006718601 /// XM_006718602 /// XM_006718603 /// XM_006718604 /// XM_006718605 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006821 // chloride transport // inferred from mutant phenotype /// 0006821 // chloride transport // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005227 // calcium activated cation channel activity // inferred from direct assay /// 0005229 // intracellular calcium activated chloride channel activity // inferred from direct assay /// 0005229 // intracellular calcium activated chloride channel activity // inferred from mutant phenotype /// 0005229 // intracellular calcium activated chloride channel activity // inferred from sequence or structural similarity /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218805_at NM_018384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018384.1 /DEF=Homo sapiens hypothetical protein FLJ11296 (FLJ11296), mRNA. /FEA=mRNA /GEN=FLJ11296 /PROD=hypothetical protein FLJ11296 /DB_XREF=gi:8922984 /UG=Hs.26194 hypothetical protein FLJ11296 /FL=gb:NM_018384.1 NM_018384 GIMAP1-GIMAP5 readthrough /// GTPase, IMAP family member 5 GIMAP1-GIMAP5 /// GIMAP5 55340 /// 100527949 NM_001199577 /// NM_018384 0001659 // temperature homeostasis // inferred from electronic annotation /// 0002729 // positive regulation of natural killer cell cytokine production // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032831 // positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 218806_s_at AF118887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF118887.1 /DEF=Homo sapiens VAV-3 protein (VAV-3) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=VAV-3 /PROD=VAV-3 protein /DB_XREF=gi:4416407 /UG=Hs.267659 vav 3 oncogene /FL=gb:AF067817.1 gb:AF118887.1 gb:NM_006113.2 AF118887 vav 3 guanine nucleotide exchange factor VAV3 10451 NM_001079874 /// NM_006113 /// XM_005270359 /// XM_005270360 /// XM_005270361 0001525 // angiogenesis // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042493 // response to drug // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // not recorded /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218807_at NM_006113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006113.2 /DEF=Homo sapiens vav 3 oncogene (VAV3), mRNA. /FEA=mRNA /GEN=VAV3 /PROD=vav 3 oncogene /DB_XREF=gi:7262390 /UG=Hs.267659 vav 3 oncogene /FL=gb:AF067817.1 gb:AF118887.1 gb:NM_006113.2 NM_006113 vav 3 guanine nucleotide exchange factor VAV3 10451 NM_001079874 /// NM_006113 /// XM_005270359 /// XM_005270360 /// XM_005270361 0001525 // angiogenesis // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042493 // response to drug // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // not recorded /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218808_at NM_018114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018114.1 /DEF=Homo sapiens hypothetical protein FLJ10496 (FLJ10496), mRNA. /FEA=mRNA /GEN=FLJ10496 /PROD=hypothetical protein FLJ10496 /DB_XREF=gi:8922464 /UG=Hs.280978 hypothetical protein FLJ10496 /FL=gb:NM_018114.1 NM_018114 DALR anticodon binding domain containing 3 DALRD3 55152 NM_001009996 /// NM_001276405 /// NM_018114 /// XM_005265266 /// XM_005265267 /// XM_005265269 /// XM_005265270 /// XM_005265272 /// XM_005265274 /// XM_006713218 /// XM_006713219 /// XR_245144 /// XR_245146 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 218809_at NM_024960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024960.1 /DEF=Homo sapiens hypothetical protein FLJ11729 (FLJ11729), mRNA. /FEA=mRNA /GEN=FLJ11729 /PROD=hypothetical protein FLJ11729 /DB_XREF=gi:13376450 /UG=Hs.286212 hypothetical protein FLJ11729 /FL=gb:NM_024960.1 NM_024960 pantothenate kinase 2 PANK2 80025 NM_024960 /// NM_153637 /// NM_153638 /// NM_153639 /// NM_153640 /// NM_153641 /// XM_005260835 /// XM_005260836 /// XM_006723631 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004594 // pantothenate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218810_at NM_025079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025079.1 /DEF=Homo sapiens hypothetical protein FLJ23231 (FLJ23231), mRNA. /FEA=mRNA /GEN=FLJ23231 /PROD=hypothetical protein FLJ23231 /DB_XREF=gi:13376631 /UG=Hs.288300 hypothetical protein FLJ23231 /FL=gb:NM_025079.1 gb:BC005001.1 NM_025079 microRNA 6732 /// zinc finger CCCH-type containing 12A MIR6732 /// ZC3H12A 80149 /// 102465438 NM_025079 /// NR_106790 /// XM_005271226 /// XM_005271227 /// XM_006710925 /// XM_006710926 0001525 // angiogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010884 // positive regulation of lipid storage // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0043031 // negative regulation of macrophage activation // inferred by curator /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218811_at BF939788 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939788 /FEA=EST /DB_XREF=gi:12357031 /DB_XREF=est:nac84c04.x1 /CLONE=IMAGE:3441007 /UG=Hs.289053 hypothetical protein FLJ12474 /FL=gb:NM_025156.1 BF939788 ORAI calcium release-activated calcium modulator 2 ORAI2 80228 NM_001126340 /// NM_001271818 /// NM_001271819 /// NM_032831 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218812_s_at NM_025156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025156.1 /DEF=Homo sapiens hypothetical protein FLJ12474 (FLJ12474), mRNA. /FEA=mRNA /GEN=FLJ12474 /PROD=hypothetical protein FLJ12474 /DB_XREF=gi:13376752 /UG=Hs.289053 hypothetical protein FLJ12474 /FL=gb:NM_025156.1 NM_025156 ORAI calcium release-activated calcium modulator 2 ORAI2 80228 NM_001126340 /// NM_001271818 /// NM_001271819 /// NM_032831 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218813_s_at NM_020145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020145.1 /DEF=Homo sapiens SH3-containing protein SH3GLB2 (LOC56904), mRNA. /FEA=mRNA /GEN=LOC56904 /PROD=SH3-containing protein SH3GLB2 /DB_XREF=gi:9910351 /UG=Hs.30002 SH3-containing protein SH3GLB2 /FL=gb:AF257319.1 gb:NM_020145.1 NM_020145 SH3-domain GRB2-like endophilin B2 SH3GLB2 56904 NM_001287045 /// NM_001287046 /// NM_020145 /// XM_005252098 /// XM_005252100 /// XM_005252101 /// XM_006717188 /// XM_006717189 /// XM_006717190 /// XM_006717191 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218814_s_at NM_018252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018252.1 /DEF=Homo sapiens hypothetical protein FLJ10874 (FLJ10874), mRNA. /FEA=mRNA /GEN=FLJ10874 /PROD=hypothetical protein FLJ10874 /DB_XREF=gi:8922727 /UG=Hs.30318 hypothetical protein FLJ10874 /FL=gb:NM_018252.1 NM_018252 transmembrane protein 206 TMEM206 55248 NM_001198862 /// NM_018252 /// XM_005273177 /// XM_006711431 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218815_s_at NM_018022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018022.1 /DEF=Homo sapiens hypothetical protein FLJ10199 (FLJ10199), mRNA. /FEA=mRNA /GEN=FLJ10199 /PROD=hypothetical protein FLJ10199 /DB_XREF=gi:8922276 /UG=Hs.30925 hypothetical protein FLJ10199 /FL=gb:BC000202.1 gb:BC000593.1 gb:NM_018022.1 NM_018022 transmembrane protein 51 TMEM51 55092 NM_001136216 /// NM_001136217 /// NM_001136218 /// NM_018022 /// XM_005245919 /// XM_006710722 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218816_at NM_018214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018214.1 /DEF=Homo sapiens hypothetical protein FLJ10775 (FLJ10775), mRNA. /FEA=mRNA /GEN=FLJ10775 /PROD=hypothetical protein FLJ10775 /DB_XREF=gi:8922660 /UG=Hs.35091 hypothetical protein FLJ10775 /FL=gb:BC003193.1 gb:NM_018214.1 NM_018214 leucine rich repeat containing 1 LRRC1 55227 NM_018214 /// NM_025168 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218817_at NM_021928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021928.1 /DEF=Homo sapiens hypothetical protein FLJ22649 similar to signal peptidase SPC2223 (FLJ22649), mRNA. /FEA=mRNA /GEN=FLJ22649 /PROD=hypothetical protein FLJ22649 similar to signalpeptidase SPC2223 /DB_XREF=gi:11345461 /UG=Hs.42194 hypothetical protein FLJ22649 similar to signal peptidase SPC2223 /FL=gb:NM_021928.1 gb:AL136660.1 NM_021928 signal peptidase complex subunit 3 homolog (S. cerevisiae) SPCS3 60559 NM_021928 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218818_at NM_004468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004468.1 /DEF=Homo sapiens four and a half LIM domains 3 (FHL3), mRNA. /FEA=mRNA /GEN=FHL3 /PROD=four and a half LIM domains 3 /DB_XREF=gi:4758373 /UG=Hs.57687 four and a half LIM domains 3 /FL=gb:BC001351.1 gb:U60116.2 gb:NM_004468.1 gb:AF133732.1 NM_004468 four and a half LIM domains 3 FHL3 2275 NM_001243878 /// NM_004468 /// XM_005270626 0007517 // muscle organ development // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218819_at NM_012141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012141.1 /DEF=Homo sapiens deleted in cancer 1; RNA helicase HDBDICE1 (DDX26), mRNA. /FEA=mRNA /GEN=DDX26 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 26 /DB_XREF=gi:11024693 /UG=Hs.58570 deleted in cancer 1; RNA helicase HDBDICE1 /FL=gb:NM_012141.1 gb:AF097645.1 NM_012141 integrator complex subunit 6 INTS6 26512 NM_001039937 /// NM_001039938 /// NM_012141 /// XM_005266340 /// XM_005266341 0007165 // signal transduction // traceable author statement /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218820_at NM_020215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020215.1 /DEF=Homo sapiens hypothetical protein DKFZp761F2014 (DKFZp761F2014), mRNA. /FEA=mRNA /GEN=DKFZp761F2014 /PROD=hypothetical protein DKFZp761F2014 /DB_XREF=gi:9910205 /UG=Hs.6434 hypothetical protein DKFZp761F2014 /FL=gb:NM_020215.1 NM_020215 chromosome 14 open reading frame 132 C14orf132 56967 NM_001252507 /// NM_001282463 /// NM_001282464 /// NM_001289139 /// NM_020215 /// NR_023938 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218821_at AL139349 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139349 /DEF=Human DNA sequence from clone RP11-261P9 on chromosome 20. Contains ESTs, STSs, GSSs and a CpG island. Contains the 3 part of the STX16 gene for syntaxin 16 and a novel gene for a protein similar to fly CG7340 /FEA=mRNA_3 /DB_XREF=gi:11544447 /UG=Hs.71746 hypothetical protein FLJ11583 /FL=gb:NM_024663.1 AL139349 uncharacterized LOC100652930 /// aminopeptidase-like 1 /// STX16-NPEPL1 readthrough (NMD candidate) LOC100652930 /// NPEPL1 /// STX16-NPEPL1 79716 /// 100534593 /// 100652930 NM_001204872 /// NM_001204873 /// NM_024663 /// NR_037945 /// XR_158947 /// XR_159361 /// XR_172328 0006508 // proteolysis // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218822_s_at NM_024663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024663.1 /DEF=Homo sapiens hypothetical protein FLJ11583 (FLJ11583), mRNA. /FEA=mRNA /GEN=FLJ11583 /PROD=hypothetical protein FLJ11583 /DB_XREF=gi:13375916 /UG=Hs.71746 hypothetical protein FLJ11583 /FL=gb:NM_024663.1 NM_024663 uncharacterized LOC100652930 /// aminopeptidase-like 1 /// STX16-NPEPL1 readthrough (NMD candidate) LOC100652930 /// NPEPL1 /// STX16-NPEPL1 79716 /// 100534593 /// 100652930 NM_001204872 /// NM_001204873 /// NM_024663 /// NR_037945 /// XR_158947 /// XR_159361 /// XR_172328 0006508 // proteolysis // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218823_s_at NM_017634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017634.1 /DEF=Homo sapiens hypothetical protein FLJ20038 (FLJ20038), mRNA. /FEA=mRNA /GEN=FLJ20038 /PROD=hypothetical protein FLJ20038 /DB_XREF=gi:8923043 /UG=Hs.72071 hypothetical protein FLJ20038 /FL=gb:NM_017634.1 NM_017634 potassium channel tetramerization domain containing 9 KCTD9 54793 NM_017634 /// XM_005273541 /// XM_005273542 /// XM_005273543 /// XM_005273544 /// XM_005273545 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218824_at NM_018215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018215.1 /DEF=Homo sapiens hypothetical protein FLJ10781 (FLJ10781), mRNA. /FEA=mRNA /GEN=FLJ10781 /PROD=hypothetical protein FLJ10781 /DB_XREF=gi:8922662 /UG=Hs.8395 hypothetical protein FLJ10781 /FL=gb:NM_018215.1 NM_018215 paraneoplastic Ma antigen family-like 1 PNMAL1 55228 NM_001103149 /// NM_018215 218825_at NM_016215 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016215.1 /DEF=Homo sapiens NEU1 protein (LOC51162), mRNA. /FEA=mRNA /GEN=LOC51162 /PROD=NEU1 protein /DB_XREF=gi:7705888 /UG=Hs.91481 NEU1 protein /FL=gb:AL512735.1 gb:AF186111.1 gb:NM_016215.1 NM_016215 EGF-like-domain, multiple 7 EGFL7 51162 NM_016215 /// NM_201446 /// NR_045110 /// NR_045111 /// NR_046367 /// XM_006717138 /// XM_006717139 /// XM_006717140 /// XM_006717141 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation 0005112 // Notch binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218826_at NM_017515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017515.1 /DEF=Homo sapiens novel protein (HSNOV1), mRNA. /FEA=mRNA /GEN=HSNOV1 /PROD=novel protein /DB_XREF=gi:13435132 /UG=Hs.9711 novel protein /FL=gb:NM_017515.1 NM_017515 solute carrier family 35, member F2 SLC35F2 54733 NM_017515 /// XM_005271598 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218827_s_at NM_018069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018069.1 /DEF=Homo sapiens hypothetical protein FLJ10352 (FLJ10352), mRNA. /FEA=mRNA /GEN=FLJ10352 /PROD=hypothetical protein FLJ10352 /DB_XREF=gi:8922371 /UG=Hs.100914 hypothetical protein FLJ10352 /FL=gb:NM_018069.1 NM_018069 centrosomal protein 192kDa CEP192 55125 NM_018069 /// NM_032142 /// XM_005258107 /// XM_005258108 /// XM_005258109 /// XM_005258110 /// XM_006722326 /// XM_006722327 /// XM_006722328 /// XM_006722329 /// XM_006722330 /// XM_006722331 /// XM_006722332 /// XR_243809 /// XR_430040 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051298 // centrosome duplication // inferred from mutant phenotype 0000242 // pericentriolar material // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 218828_at NM_020360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020360.1 /DEF=Homo sapiens phospholipid scramblase 3 (PLSCR3), mRNA. /FEA=mRNA /GEN=PLSCR3 /PROD=phospholipid scramblase 3 /DB_XREF=gi:9966796 /UG=Hs.103382 phospholipid scramblase 3 /FL=gb:AF159442.1 gb:NM_020360.1 NM_020360 phospholipid scramblase 3 /// TMEM256-PLSCR3 readthrough (NMD candidate) PLSCR3 /// TMEM256-PLSCR3 57048 /// 100529211 NM_001201576 /// NM_020360 /// NR_037719 0006915 // apoptotic process // inferred from electronic annotation /// 0017121 // phospholipid scrambling // non-traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0017128 // phospholipid scramblase activity // non-traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 218829_s_at NM_017780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017780.1 /DEF=Homo sapiens hypothetical protein FLJ20357 (FLJ20357), mRNA. /FEA=mRNA /GEN=FLJ20357 /PROD=hypothetical protein FLJ20357 /DB_XREF=gi:8923329 /UG=Hs.105461 hypothetical protein FLJ20357 /FL=gb:NM_017780.1 NM_017780 chromodomain helicase DNA binding protein 7 CHD7 55636 NM_017780 /// XM_005251266 /// XM_005251267 /// XM_006716459 /// XM_006716460 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007512 // adult heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008015 // blood circulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from mutant phenotype /// 0030217 // T cell differentiation // inferred from mutant phenotype /// 0030540 // female genitalia development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043584 // nose development // inferred from mutant phenotype /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from mutant phenotype /// 0060123 // regulation of growth hormone secretion // inferred from mutant phenotype /// 0060173 // limb development // inferred from mutant phenotype /// 0060324 // face development // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 218830_at NM_016093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016093.1 /DEF=Homo sapiens ribosomal protein L26 homolog (LOC51121), mRNA. /FEA=mRNA /GEN=LOC51121 /PROD=ribosomal protein L26 homolog /DB_XREF=gi:7705812 /UG=Hs.110165 ribosomal protein L26 homolog /FL=gb:AF083248.1 gb:NM_016093.1 NM_016093 ribosomal protein L26-like 1 RPL26L1 51121 NM_016093 /// XM_005265921 /// XM_005265922 /// XM_005265923 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation 218831_s_at NM_004107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004107.1 /DEF=Homo sapiens Fc fragment of IgG, receptor, transporter, alpha (FCGRT), mRNA. /FEA=mRNA /GEN=FCGRT /PROD=Fc fragment of IgG, receptor, transporter,alpha /DB_XREF=gi:4758345 /UG=Hs.111903 Fc fragment of IgG, receptor, transporter, alpha /FL=gb:NM_004107.1 gb:U12255.1 NM_004107 Fc fragment of IgG, receptor, transporter, alpha FCGRT 2217 NM_001136019 /// NM_004107 /// XM_005258657 /// XM_006723086 0002416 // IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0038094 // Fc-gamma receptor signaling pathway // not recorded 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003823 // antigen binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0019770 // IgG receptor activity // not recorded /// 0019864 // IgG binding // inferred from direct assay /// 0030881 // beta-2-microglobulin binding // not recorded 218832_x_at NM_004041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004041.2 /DEF=Homo sapiens arrestin, beta 1 (ARRB1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ARRB1 /PROD=arrestin beta 1, isoform A /DB_XREF=gi:10880135 /UG=Hs.112278 arrestin, beta 1 /FL=gb:NM_004041.2 gb:BC003636.1 gb:AF084040.1 NM_004041 arrestin, beta 1 ARRB1 408 NM_004041 /// NM_020251 /// XM_005273997 /// XM_005273998 /// XM_006718552 /// XM_006718553 /// XM_006718554 /// XM_006718555 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090240 // positive regulation of histone H4 acetylation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031143 // pseudopodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031896 // V2 vasopressin receptor binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 218833_at NM_016653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016653.1 /DEF=Homo sapiens sterile-alpha motif and leucine zipper containing kinase AZK (ZAK), mRNA. /FEA=mRNA /GEN=ZAK /PROD=sterile-alpha motif and leucine zippercontaining kinase AZK /DB_XREF=gi:7706600 /UG=Hs.115175 sterile-alpha motif and leucine zipper containing kinase AZK /FL=gb:AB049733.1 gb:AF238255.1 gb:AF251441.1 gb:NM_016653.1 gb:AB030034.1 NM_016653 sterile alpha motif and leucine zipper containing kinase AZK ZAK 51776 NM_016653 /// NM_133646 /// XM_005246640 0000075 // cell cycle checkpoint // inferred from direct assay /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006950 // response to stress // non-traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007257 // activation of JUN kinase activity // inferred from direct assay /// 0008219 // cell death // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0009314 // response to radiation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218834_s_at NM_017870 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017870.1 /DEF=Homo sapiens hypothetical protein FLJ20539 (FLJ20539), mRNA. /FEA=mRNA /GEN=FLJ20539 /PROD=hypothetical protein FLJ20539 /DB_XREF=gi:8923509 /UG=Hs.118552 hypothetical protein FLJ20539 /FL=gb:NM_017870.1 NM_017870 transmembrane protein 132A TMEM132A 54972 NM_017870 /// NM_178031 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218835_at NM_006926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006926.1 /DEF=Homo sapiens surfactant, pulmonary-associated protein A2 (SFTPA2), mRNA. /FEA=mRNA /GEN=SFTPA2 /PROD=surfactant, pulmonary-associated protein A2 /DB_XREF=gi:13346505 /UG=Hs.177582 surfactant, pulmonary-associated protein A2 /FL=gb:NM_006926.1 NM_006926 surfactant protein A1 /// surfactant protein A2 SFTPA1 /// SFTPA2 653509 /// 729238 NM_001093770 /// NM_001098668 /// NM_001164644 /// NM_001164645 /// NM_001164646 /// NM_001164647 /// NM_005411 /// XM_005270061 /// XM_005270062 /// XM_005270128 /// XM_005270129 /// XM_005270131 /// XM_005270132 /// XM_006717953 /// XM_006717954 0006869 // lipid transport // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005319 // lipid transporter activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 218836_at NM_024839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024839.1 /DEF=Homo sapiens hypothetical protein FLJ22638 (FLJ22638), mRNA. /FEA=mRNA /GEN=FLJ22638 /PROD=hypothetical protein FLJ22638 /DB_XREF=gi:13376252 /UG=Hs.183232 hypothetical protein FLJ22638 /FL=gb:NM_024839.1 NM_024839 ribonuclease P/MRP 21kDa subunit /// tripartite motif containing 39 /// TRIM39-RPP21 readthrough RPP21 /// TRIM39 /// TRIM39-RPP21 56658 /// 79897 /// 202658 NM_001199119 /// NM_001199120 /// NM_001199121 /// NM_021253 /// NM_024839 /// NM_172016 0006915 // apoptotic process // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218837_s_at NM_015983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015983.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme HBUCE1 (LOC51619), mRNA. /FEA=mRNA /GEN=LOC51619 /PROD=ubiquitin-conjugating enzyme HBUCE1 /DB_XREF=gi:8393718 /UG=Hs.19196 ubiquitin-conjugating enzyme HBUCE1 /FL=gb:BC004104.1 gb:NM_015983.1 NM_015983 ubiquitin-conjugating enzyme E2D 4 (putative) UBE2D4 51619 NM_015983 /// XM_005249772 /// XM_006715734 /// XM_006715735 /// XM_006715736 /// XM_006715737 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 218838_s_at NM_022492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022492.1 /DEF=Homo sapiens hypothetical protein FLJ12788 (FLJ12788), mRNA. /FEA=mRNA /GEN=FLJ12788 /PROD=hypothetical protein FLJ12788 /DB_XREF=gi:11968048 /UG=Hs.20242 hypothetical protein FLJ12788 /FL=gb:NM_022492.1 NM_022492 tetratricopeptide repeat domain 31 TTC31 64427 NM_022492 /// NR_027749 /// XM_005264491 /// XM_005264492 /// XM_005264493 /// XM_005264496 /// XM_005264497 /// XM_006712077 /// XR_244951 /// XR_244952 0005515 // protein binding // inferred from electronic annotation 218839_at NM_012258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012258.1 /DEF=Homo sapiens hairyenhancer-of-split related with YRPW motif 1 (HEY1), mRNA. /FEA=mRNA /GEN=HEY1 /PROD=hairyenhancer-of-split related with YRPW motif1 /DB_XREF=gi:6912411 /UG=Hs.234434 hairyenhancer-of-split related with YRPW motif 1 /FL=gb:AF311883.1 gb:BC001873.1 gb:AF151522.1 gb:AF176422.1 gb:NM_012258.1 gb:AF232239.1 NM_012258 hes-related family bHLH transcription factor with YRPW motif 1 HEY1 23462 NM_001040708 /// NM_001282851 /// NM_012258 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003190 // atrioventricular valve formation // inferred from sequence or structural similarity /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036304 // umbilical cord morphogenesis // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000820 // negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from direct assay /// 2001212 // regulation of vasculogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 218840_s_at NM_018161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018161.1 /DEF=Homo sapiens hypothetical protein FLJ10631 (FLJ10631), mRNA. /FEA=mRNA /GEN=FLJ10631 /PROD=hypothetical protein FLJ10631 /DB_XREF=gi:8922560 /UG=Hs.238944 hypothetical protein FLJ10631 /FL=gb:BC003638.1 gb:BC003666.1 gb:NM_018161.1 NM_018161 NAD synthetase 1 NADSYN1 55191 NM_018161 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003952 // NAD+ synthase (glutamine-hydrolyzing) activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 218841_at NM_024095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024095.1 /DEF=Homo sapiens hypothetical protein MGC5540 (MGC5540), mRNA. /FEA=mRNA /GEN=MGC5540 /PROD=hypothetical protein MGC5540 /DB_XREF=gi:13129097 /UG=Hs.267400 hypothetical protein MGC5540 /FL=gb:BC001321.1 gb:NM_024095.1 NM_024095 ankyrin repeat and SOCS box containing 8 ASB8 140461 NM_024095 /// XM_005268654 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218842_at NM_024604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024604.1 /DEF=Homo sapiens hypothetical protein FLJ21908 (FLJ21908), mRNA. /FEA=mRNA /GEN=FLJ21908 /PROD=hypothetical protein FLJ21908 /DB_XREF=gi:13375808 /UG=Hs.26750 hypothetical protein FLJ21908 /FL=gb:NM_024604.1 NM_024604 RNA polymerase II associated protein 3 RPAP3 79657 NM_001146075 /// NM_001146076 /// NM_024604 0005515 // protein binding // inferred from physical interaction 218843_at NM_022823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022823.1 /DEF=Homo sapiens hypothetical protein FLJ22362 (FLJ22362), mRNA. /FEA=mRNA /GEN=FLJ22362 /PROD=hypothetical protein FLJ22362 /DB_XREF=gi:12383063 /UG=Hs.27836 hypothetical protein FLJ22362 /FL=gb:NM_022823.1 NM_022823 fibronectin type III domain containing 4 FNDC4 64838 NM_022823 /// XM_005264499 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218844_at NM_025149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025149.1 /DEF=Homo sapiens hypothetical protein FLJ20920 (FLJ20920), mRNA. /FEA=mRNA /GEN=FLJ20920 /PROD=hypothetical protein FLJ20920 /DB_XREF=gi:13376740 /UG=Hs.288959 hypothetical protein FLJ20920 /FL=gb:NM_025149.1 NM_025149 acyl-CoA synthetase family member 2 ACSF2 80221 NM_001288968 /// NM_001288969 /// NM_001288970 /// NM_001288971 /// NM_001288972 /// NM_025149 /// NR_110232 /// XM_006722110 /// XR_429924 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 218845_at NM_020185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020185.1 /DEF=Homo sapiens mitogen-activated protein kinase phosphatase x (MKPX), mRNA. /FEA=mRNA /GEN=MKPX /PROD=mitogen-activated protein kinase phosphatase x /DB_XREF=gi:9910431 /UG=Hs.29106 mitogen-activated protein kinase phosphatase x /FL=gb:AF165519.1 gb:NM_020185.1 NM_020185 dual specificity phosphatase 22 DUSP22 56940 NM_001286555 /// NM_020185 /// NR_104473 /// NR_104474 /// NR_104475 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000188 // inactivation of MAPK activity // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0006915 // apoptotic process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // not recorded /// 0046330 // positive regulation of JNK cascade // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 218846_at NM_004830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004830.1 /DEF=Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3 (130kD) (CRSP3), mRNA. /FEA=mRNA /GEN=CRSP3 /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 3 (130kD) /DB_XREF=gi:7019352 /UG=Hs.29679 cofactor required for Sp1 transcriptional activation, subunit 3 (130kD) /FL=gb:AF135022.1 gb:AF105332.1 gb:NM_004830.1 NM_004830 mediator complex subunit 23 MED23 9439 NM_001270521 /// NM_001270522 /// NM_004830 /// NM_015979 /// XM_005267223 /// XM_006715612 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218847_at NM_006548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006548.1 /DEF=Homo sapiens IGF-II mRNA-binding protein 2 (IMP-2), mRNA. /FEA=mRNA /GEN=IMP-2 /PROD=IGF-II mRNA-binding protein 2 /DB_XREF=gi:5729883 /UG=Hs.30299 IGF-II mRNA-binding protein 2 /FL=gb:AF057352.1 gb:NM_006548.1 NM_006548 insulin-like growth factor 2 mRNA binding protein 2 IGF2BP2 10644 NM_001007225 /// NM_001291869 /// NM_001291872 /// NM_001291873 /// NM_001291874 /// NM_001291875 /// NM_006548 /// XM_006713477 /// XM_006713478 /// XR_427358 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 218848_at NM_024339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024339.1 /DEF=Homo sapiens hypothetical protein MGC2655 (MGC2655), mRNA. /FEA=mRNA /GEN=MGC2655 /PROD=hypothetical protein MGC2655 /DB_XREF=gi:13236588 /UG=Hs.314807 hypothetical protein MGC2655 /FL=gb:BC003118.1 gb:NM_024339.1 NM_024339 THO complex 6 homolog (Drosophila) THOC6 79228 NM_001142350 /// NM_024339 /// XM_006720946 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218849_s_at NM_006663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006663.1 /DEF=Homo sapiens RelA-associated inhibitor (RAI), mRNA. /FEA=mRNA /GEN=RAI /PROD=RelA-associated inhibitor /DB_XREF=gi:5730000 /UG=Hs.324051 RelA-associated inhibitor /FL=gb:AF078037.1 gb:NM_006663.1 NM_006663 protein phosphatase 1, regulatory subunit 13 like PPP1R13L 10848 NM_001142502 /// NM_006663 /// XM_005258424 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003229 // ventricular cardiac muscle tissue development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042633 // hair cycle // inferred from electronic annotation /// 0048871 // multicellular organismal homeostasis // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 218850_s_at NM_014240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014240.1 /DEF=Homo sapiens LIM domains containing 1 (LIMD1), mRNA. /FEA=mRNA /GEN=LIMD1 /PROD=LIM domains containing 1 /DB_XREF=gi:7657306 /UG=Hs.48469 LIM domains containing 1 /FL=gb:NM_014240.1 NM_014240 LIM domains containing 1 LIMD1 8994 NM_014240 /// XM_005265529 /// XM_005265530 /// XM_006713381 0001666 // response to hypoxia // inferred from direct assay /// 0002076 // osteoblast development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0035195 // gene silencing by miRNA // inferred from mutant phenotype /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000637 // positive regulation of gene silencing by miRNA // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218851_s_at NM_018383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018383.1 /DEF=Homo sapiens hypothetical protein FLJ11294 (FLJ11294), mRNA. /FEA=mRNA /GEN=FLJ11294 /PROD=hypothetical protein FLJ11294 /DB_XREF=gi:8922982 /UG=Hs.48541 hypothetical protein FLJ11294 /FL=gb:NM_018383.1 NM_018383 SFT2 domain containing 3 /// WD repeat domain 33 SFT2D3 /// WDR33 55339 /// 84826 NM_001006622 /// NM_001006623 /// NM_018383 /// NM_032740 /// XM_005263697 0006301 // postreplication repair // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218852_at NM_017917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017917.1 /DEF=Homo sapiens hypothetical protein FLJ20644 (FLJ20644), mRNA. /FEA=mRNA /GEN=FLJ20644 /PROD=hypothetical protein FLJ20644 /DB_XREF=gi:8923599 /UG=Hs.49376 hypothetical protein FLJ20644 /FL=gb:NM_017917.1 NM_017917 protein phosphatase 2, regulatory subunit B'', gamma PPP2R3C 55012 NM_017917 /// XM_005267782 /// XM_005267784 /// XM_006720181 /// XM_006720182 /// XM_006720183 /// XM_006720184 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002759 // regulation of antimicrobial humoral response // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0050864 // regulation of B cell activation // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218853_s_at NM_019556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019556.1 /DEF=Homo sapiens hypothetical protein dJ473B4 (DJ473B4), mRNA. /FEA=mRNA /GEN=DJ473B4 /PROD=hypothetical protein dJ473B4 /DB_XREF=gi:9506542 /UG=Hs.57549 hypothetical protein dJ473B4 /FL=gb:NM_019556.1 NM_019556 motile sperm domain containing 1 MOSPD1 56180 NM_019556 /// XM_005262446 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005198 // structural molecule activity // inferred from electronic annotation 218854_at NM_013352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013352.1 /DEF=Homo sapiens squamous cell carcinoma antigen recognized by T cell (SART-2), mRNA. /FEA=mRNA /GEN=SART-2 /PROD=squamous cell carcinoma antigen recognized by Tcell /DB_XREF=gi:7019520 /UG=Hs.58636 squamous cell carcinoma antigen recognized by T cell /FL=gb:AF098066.1 gb:NM_013352.1 NM_013352 dermatan sulfate epimerase DSE 29940 NM_001080976 /// NM_013352 /// XM_005266953 0005975 // carbohydrate metabolic process // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0030208 // dermatan sulfate biosynthetic process // inferred from direct assay /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0047757 // chondroitin-glucuronate 5-epimerase activity // inferred from direct assay 218855_at NM_016372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016372.1 /DEF=Homo sapiens seven transmembrane domain orphan receptor (LOC51210), mRNA. /FEA=mRNA /GEN=LOC51210 /PROD=seven transmembrane domain orphan receptor /DB_XREF=gi:7705964 /UG=Hs.6418 seven transmembrane domain orphan receptor /FL=gb:AB037108.1 gb:NM_016372.1 NM_016372 transmembrane protein, adipocyte asscociated 1 TPRA1 131601 NM_001136053 /// NM_001142646 /// NM_016372 /// NR_073377 /// XM_006713495 /// XM_006713496 /// XM_006713497 0006629 // lipid metabolic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007568 // aging // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004930 // G-protein coupled receptor activity // traceable author statement 218856_at NM_016629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016629.1 /DEF=Homo sapiens hypothetical protein (LOC51323), mRNA. /FEA=mRNA /GEN=LOC51323 /PROD=hypothetical protein /DB_XREF=gi:7706171 /UG=Hs.65403 hypothetical protein /FL=gb:BC005192.1 gb:AF208860.1 gb:NM_016629.1 NM_016629 tumor necrosis factor receptor superfamily, member 21 TNFRSF21 27242 NM_014452 0001783 // B cell apoptotic process // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031642 // negative regulation of myelination // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048713 // regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0097252 // oligodendrocyte apoptotic process // inferred from sequence or structural similarity /// 2000663 // negative regulation of interleukin-5 secretion // inferred from sequence or structural similarity /// 2000666 // negative regulation of interleukin-13 secretion // inferred from sequence or structural similarity /// 2001180 // negative regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 218857_s_at NM_025080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025080.1 /DEF=Homo sapiens hypothetical protein FLJ22316 (FLJ22316), mRNA. /FEA=mRNA /GEN=FLJ22316 /PROD=hypothetical protein FLJ22316 /DB_XREF=gi:13376633 /UG=Hs.7331 hypothetical protein FLJ22316 /FL=gb:NM_025080.1 NM_025080 asparaginase like 1 ASRGL1 80150 NM_001083926 /// NM_025080 /// XM_005274304 /// XM_005274305 /// XM_005274306 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033345 // asparagine catabolic process via L-aspartate // inferred from direct assay /// 0033345 // asparagine catabolic process via L-aspartate // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0004067 // asparaginase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008798 // beta-aspartyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 218858_at NM_022783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022783.1 /DEF=Homo sapiens hypothetical protein FLJ12428 (FLJ12428), mRNA. /FEA=mRNA /GEN=FLJ12428 /PROD=hypothetical protein FLJ12428 /DB_XREF=gi:12232472 /UG=Hs.87729 hypothetical protein FLJ12428 /FL=gb:AL136678.1 gb:NM_022783.1 NM_022783 DEP domain containing MTOR-interacting protein DEPTOR 64798 NM_001283012 /// NM_022783 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045792 // negative regulation of cell size // inferred from mutant phenotype /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218859_s_at NM_016649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016649.1 /DEF=Homo sapiens HDCMC28P protein (HDCMC28P), mRNA. /FEA=mRNA /GEN=HDCMC28P /PROD=HDCMC28P protein /DB_XREF=gi:7705402 /UG=Hs.88820 HDCMC28P protein /FL=gb:AF068285.1 gb:NM_016649.1 NM_016649 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) ESF1 51575 NM_001276380 /// NM_016649 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 218860_at NM_024078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024078.1 /DEF=Homo sapiens hypothetical protein MGC3162 (MGC3162), mRNA. /FEA=mRNA /GEN=MGC3162 /PROD=hypothetical protein MGC3162 /DB_XREF=gi:13129067 /UG=Hs.95196 hypothetical protein MGC3162 /FL=gb:BC001191.1 gb:NM_024078.1 NM_024078 nucleolar complex associated 4 homolog (S. cerevisiae) NOC4L 79050 NM_024078 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218861_at NM_022453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022453.1 /DEF=Homo sapiens hypothetical protein FLJ13906 similar to RING finger protein (FLJ13906), mRNA. /FEA=mRNA /GEN=FLJ13906 /PROD=hypothetical protein FLJ13906 similar to RINGfinger protein /DB_XREF=gi:11967988 /UG=Hs.97176 hypothetical protein FLJ13906 similar to RING finger protein /FL=gb:NM_022453.1 NM_022453 ring finger protein 25 RNF25 64320 NM_022453 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction 218862_at NM_024701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024701.1 /DEF=Homo sapiens hypothetical protein FLJ13134 (FLJ13134), mRNA. /FEA=mRNA /GEN=FLJ13134 /PROD=hypothetical protein FLJ13134 /DB_XREF=gi:13375988 /UG=Hs.99603 hypothetical protein FLJ13134 /FL=gb:NM_024701.1 NM_024701 ankyrin repeat and SOCS box containing 13 ASB13 79754 NM_024701 /// NR_024581 /// NR_037164 /// XM_006717507 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218863_s_at NM_022648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022648.1 /DEF=Homo sapiens tensin (TNS), mRNA. /FEA=mRNA /GEN=TNS /PROD=tensin /DB_XREF=gi:12408639 /UG=Hs.9973 tensin /FL=gb:NM_022648.1 gb:AF116610.1 NM_022648 tensin 1 TNS1 7145 NM_022648 /// XM_005246825 /// XM_005246826 /// XM_006712721 /// XM_006712722 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218864_at AF116610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF116610.1 /DEF=Homo sapiens PRO0929 mRNA, complete cds. /FEA=mRNA /PROD=PRO0929 /DB_XREF=gi:7959723 /UG=Hs.9973 tensin /FL=gb:NM_022648.1 gb:AF116610.1 AF116610 tensin 1 TNS1 7145 NM_022648 /// XM_005246825 /// XM_005246826 /// XM_006712721 /// XM_006712722 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218865_at NM_022746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022746.1 /DEF=Homo sapiens hypothetical protein FLJ22390 (FLJ22390), mRNA. /FEA=mRNA /GEN=FLJ22390 /PROD=hypothetical protein FLJ22390 /DB_XREF=gi:12232404 /UG=Hs.10974 hypothetical protein FLJ22390 /FL=gb:NM_022746.1 NM_022746 mitochondrial amidoxime reducing component 1 MARC1 64757 NM_022746 0008152 // metabolic process // inferred from electronic annotation /// 0042126 // nitrate metabolic process // inferred from direct assay /// 0051410 // detoxification of nitrogen compound // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008940 // nitrate reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from direct assay 218866_s_at NM_016310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016310.1 /DEF=Homo sapiens polymerase (RNA) III (DNA directed) polypeptide K (12.3 kDa) (POLR3K), mRNA. /FEA=mRNA /GEN=POLR3K /PROD=polymerase (RNA) III (DNA directed) polypeptideK (12.3 kDa) /DB_XREF=gi:7706498 /UG=Hs.110857 polymerase (RNA) III (DNA directed) polypeptide K (12.3 kDa) /FL=gb:AF060223.1 gb:AF051316.1 gb:NM_016310.1 NM_016310 polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa POLR3K 51728 NM_016310 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // not recorded /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218867_s_at NM_024738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024738.1 /DEF=Homo sapiens hypothetical protein FLJ21415 (FLJ21415), mRNA. /FEA=mRNA /GEN=FLJ21415 /PROD=hypothetical protein FLJ21415 /DB_XREF=gi:13376059 /UG=Hs.120170 hypothetical protein FLJ21415 /FL=gb:NM_024738.1 NM_024738 chromosome 12 open reading frame 49 C12orf49 79794 NM_024738 /// XM_005253937 0005576 // extracellular region // inferred from electronic annotation 218868_at NM_020445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020445.1 /DEF=Homo sapiens actin-related protein 3-beta (ARP3BETA), mRNA. /FEA=mRNA /GEN=ARP3BETA /PROD=actin-related protein 3-beta /DB_XREF=gi:9966912 /UG=Hs.12887 actin-related protein 3-beta /FL=gb:AF023453.1 gb:NM_020445.1 NM_020445 ARP3 actin-related protein 3 homolog B (yeast) ACTR3B 57180 NM_001040135 /// NM_020445 /// NR_073000 /// NR_073001 /// XM_006716064 /// XM_006716065 /// XM_006716066 /// XM_006716067 /// XM_006716068 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 218869_at NM_012213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012213.1 /DEF=Homo sapiens malonyl-CoA decarboxylase (MLYCD), mRNA. /FEA=mRNA /GEN=MLYCD /PROD=malonyl-CoA decarboxylase /DB_XREF=gi:6912497 /UG=Hs.150748 malonyl-CoA decarboxylase /FL=gb:BC000286.1 gb:AF153679.1 gb:AF097832.2 gb:AF090834.1 gb:NM_012213.1 NM_012213 malonyl-CoA decarboxylase MLYCD 23417 NM_012213 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006085 // acetyl-CoA biosynthetic process // inferred from direct assay /// 0006085 // acetyl-CoA biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0046321 // positive regulation of fatty acid oxidation // inferred from mutant phenotype /// 2001294 // malonyl-CoA catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from sequence or structural similarity /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0050080 // malonyl-CoA decarboxylase activity // inferred from direct assay 218870_at NM_018460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018460.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM046 (BM046), mRNA. /FEA=mRNA /GEN=BM046 /PROD=uncharacterized bone marrow protein BM046 /DB_XREF=gi:8922105 /UG=Hs.177812 uncharacterized bone marrow protein BM046 /FL=gb:AF217507.1 gb:AF217522.1 gb:NM_018460.1 gb:AF212222.1 NM_018460 Rho GTPase activating protein 15 /// uncharacterized LOC101928361 ARHGAP15 /// LOC101928361 55843 /// 101928361 NM_018460 /// XM_005263714 /// XM_006712632 /// XR_244865 /// XR_249211 /// XR_251188 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay 218871_x_at NM_018590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018590.1 /DEF=Homo sapiens hypothetical protein PRO0082 (PRO0082), mRNA. /FEA=mRNA /GEN=PRO0082 /PROD=hypothetical protein PRO0082 /DB_XREF=gi:8923965 /UG=Hs.180758 hypothetical protein PRO0082 /FL=gb:AF116646.1 gb:NM_018590.1 NM_018590 chondroitin sulfate N-acetylgalactosaminyltransferase 2 CSGALNACT2 55454 NM_018590 /// XM_005271819 /// XM_005271820 /// XM_005271821 0005975 // carbohydrate metabolic process // traceable author statement /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050652 // dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // traceable author statement /// 0050653 // chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008376 // acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047237 // glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation 218872_at NM_017899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017899.1 /DEF=Homo sapiens hypothetical protein FLJ20607 (FLJ20607), mRNA. /FEA=mRNA /GEN=FLJ20607 /PROD=hypothetical protein FLJ20607 /DB_XREF=gi:8923562 /UG=Hs.18791 hypothetical protein FLJ20607 /FL=gb:NM_017899.1 NM_017899 tescalcin TESC 54997 NM_001168325 /// NM_017899 /// NR_031766 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008584 // male gonad development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030219 // megakaryocyte differentiation // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from direct assay /// 0032417 // positive regulation of sodium:proton antiporter activity // inferred from direct assay /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from direct assay /// 0051604 // protein maturation // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0001726 // ruffle // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 218873_at NM_017710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017710.1 /DEF=Homo sapiens hypothetical protein FLJ20203 (FLJ20203), mRNA. /FEA=mRNA /GEN=FLJ20203 /PROD=hypothetical protein FLJ20203 /DB_XREF=gi:8923193 /UG=Hs.20594 hypothetical protein FLJ20203 /FL=gb:NM_017710.1 NM_017710 gon-4-like (C. elegans) GON4L 54856 NM_001037533 /// NM_001282856 /// NM_001282858 /// NM_001282860 /// NM_001282861 /// NM_032292 /// XM_005245283 /// XM_005245284 /// XM_005245286 /// XM_006711393 /// XM_006711394 /// XM_006711395 /// XM_006711396 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 218874_s_at NM_024909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024909.1 /DEF=Homo sapiens hypothetical protein FLJ13158 (FLJ13158), mRNA. /FEA=mRNA /GEN=FLJ13158 /PROD=hypothetical protein FLJ13158 /DB_XREF=gi:13376368 /UG=Hs.250173 hypothetical protein FLJ13158 /FL=gb:NM_024909.1 NM_024909 alpha tubulin acetyltransferase 1 ATAT1 79969 NM_001031722 /// NM_001190724 /// NM_001254952 /// NM_024909 /// NR_033821 /// NR_033823 /// XM_005249414 /// XM_005249415 /// XM_005249416 /// XM_005249417 /// XM_005249418 /// XM_005249419 /// XM_005249420 /// XM_005249421 /// XM_005249422 /// XM_005272895 /// XM_005272896 /// XM_005272897 /// XM_005272898 /// XM_005272899 /// XM_005272900 /// XM_005272901 /// XM_005272902 /// XM_005272903 /// XM_005275050 /// XM_005275051 /// XM_005275052 /// XM_005275053 /// XM_005275054 /// XM_005275055 /// XM_005275056 /// XM_005275057 /// XM_005275058 /// XM_005275185 /// XM_005275186 /// XM_005275187 /// XM_005275188 /// XM_005275189 /// XM_005275190 /// XM_005275191 /// XM_005275192 /// XM_005275193 /// XM_005275307 /// XM_005275308 /// XM_005275309 /// XM_005275310 /// XM_005275311 /// XM_005275312 /// XM_005275313 /// XM_005275314 /// XM_005275315 /// XM_005275480 /// XM_005275481 /// XM_005275482 /// XM_005275483 /// XM_005275484 /// XM_005275485 /// XM_005275486 /// XM_005275487 /// XM_005275488 /// XM_005275611 /// XM_005275612 /// XM_005275613 /// XM_005275614 /// XM_005275615 /// XM_005275616 /// XM_005275617 /// XM_005275618 /// XM_005275619 /// XM_006715214 /// XM_006725528 /// XM_006725747 /// XM_006725854 /// XM_006725943 /// XM_006726044 /// XM_006726132 /// XR_241917 /// XR_241918 /// XR_241919 /// XR_241920 /// XR_246968 /// XR_246969 /// XR_246970 /// XR_246971 /// XR_247355 /// XR_247356 /// XR_247357 /// XR_247358 /// XR_247376 /// XR_247377 /// XR_247378 /// XR_247379 /// XR_247391 /// XR_247392 /// XR_247393 /// XR_247394 /// XR_247407 /// XR_247408 /// XR_247409 /// XR_247410 /// XR_247428 /// XR_247429 /// XR_247430 /// XR_247431 0048666 // neuron development // inferred from electronic annotation /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from electronic annotation /// 0071929 // alpha-tubulin acetylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019799 // tubulin N-acetyltransferase activity // inferred from mutant phenotype 218875_s_at NM_012177 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012177.1 /DEF=Homo sapiens F-box only protein 5 (FBXO5), mRNA. /FEA=mRNA /GEN=FBXO5 /PROD=F-box only protein 5 /DB_XREF=gi:6912365 /UG=Hs.272027 F-box only protein 5 /FL=gb:AF129535.1 gb:NM_012177.1 NM_012177 F-box protein 5 FBXO5 26271 NM_001142522 /// NM_012177 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007057 // spindle assembly involved in female meiosis I // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0016050 // vesicle organization // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0046785 // microtubule polymerization // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0060565 // inhibition of mitotic anaphase-promoting complex activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218876_at NM_016140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016140.1 /DEF=Homo sapiens brain specific protein (LOC51673), mRNA. /FEA=mRNA /GEN=LOC51673 /PROD=brain specific protein /DB_XREF=gi:7706392 /UG=Hs.279772 brain specific protein /FL=gb:BC000691.1 gb:AF132972.1 gb:AF078846.1 gb:NM_015964.1 gb:NM_016140.1 NM_016140 tubulin polymerization-promoting protein family member 3 TPPP3 51673 NM_015964 /// NM_016140 /// XM_005255979 0001578 // microtubule bundle formation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015631 // tubulin binding // inferred from direct assay 218877_s_at NM_021820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021820.1 /DEF=Homo sapiens MDS024 protein (MDS024), mRNA. /FEA=mRNA /GEN=MDS024 /PROD=MDS024 protein /DB_XREF=gi:11141892 /UG=Hs.286122 MDS024 protein /FL=gb:AF182423.1 gb:NM_021820.1 NM_021820 tRNA methyltransferase 11 homolog (S. cerevisiae) TRMT11 60487 NM_001031712 /// NM_021820 /// XM_006715546 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218878_s_at NM_012238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012238.3 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1 (SIRT1), mRNA. /FEA=mRNA /GEN=SIRT1 /PROD=sirtuin 1 /DB_XREF=gi:13775598 /UG=Hs.31176 sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1 /FL=gb:NM_012238.3 gb:AF083106.2 NM_012238 sirtuin 1 SIRT1 23411 NM_001142498 /// NM_012238 /// XM_005269663 /// XM_006717737 0000012 // single strand break repair // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from mutant phenotype /// 0000731 // DNA synthesis involved in DNA repair // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from direct assay /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001678 // cellular glucose homeostasis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002821 // positive regulation of adaptive immune response // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006325 // chromatin organization // inferred from mutant phenotype /// 0006342 // chromatin silencing // traceable author statement /// 0006343 // establishment of chromatin silencing // inferred from direct assay /// 0006344 // maintenance of chromatin silencing // inferred from mutant phenotype /// 0006346 // methylation-dependent chromatin silencing // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0006476 // protein deacetylation // inferred from mutant phenotype /// 0006642 // triglyceride mobilization // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from direct assay /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007569 // cell aging // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0016239 // positive regulation of macroautophagy // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0018394 // peptidyl-lysine acetylation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0031393 // negative regulation of prostaglandin biosynthetic process // inferred from sequence or structural similarity /// 0031648 // protein destabilization // inferred from sequence or structural similarity /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031937 // positive regulation of chromatin silencing // inferred from mutant phenotype /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0033158 // regulation of protein import into nucleus, translocation // inferred from mutant phenotype /// 0034391 // regulation of smooth muscle cell apoptotic process // inferred from sequence or structural similarity /// 0034983 // peptidyl-lysine deacetylation // inferred from direct assay /// 0035356 // cellular triglyceride homeostasis // inferred from sequence or structural similarity /// 0035358 // regulation of peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042326 // negative regulation of phosphorylation // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051097 // negative regulation of helicase activity // inferred from direct assay /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0055089 // fatty acid homeostasis // inferred from sequence or structural similarity /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070857 // regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070932 // histone H3 deacetylation // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0071479 // cellular response to ionizing radiation // inferred from sequence or structural similarity /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 2000111 // positive regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from mutant phenotype /// 2000655 // negative regulation of cellular response to testosterone stimulus // inferred from mutant phenotype /// 2000757 // negative regulation of peptidyl-lysine acetylation // inferred from direct assay /// 2000773 // negative regulation of cellular senescence // inferred from direct assay /// 2000774 // positive regulation of cellular senescence // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0033553 // rDNA heterochromatin // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017136 // NAD-dependent histone deacetylase activity // inferred from direct assay /// 0019213 // deacetylase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0034979 // NAD-dependent protein deacetylase activity // inferred from direct assay /// 0034979 // NAD-dependent protein deacetylase activity // inferred from mutant phenotype /// 0042393 // histone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043398 // HLH domain binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from sequence or structural similarity /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction /// 0070403 // NAD+ binding // inferred from electronic annotation /// 1990254 // keratin filament binding // inferred from physical interaction 218879_s_at NM_022764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022764.1 /DEF=Homo sapiens hypothetical protein FLJ12998 (FLJ12998), mRNA. /FEA=mRNA /GEN=FLJ12998 /PROD=hypothetical protein FLJ12998 /DB_XREF=gi:12232436 /UG=Hs.32491 hypothetical protein FLJ12998 /FL=gb:NM_022764.1 NM_022764 methenyltetrahydrofolate synthetase domain containing MTHFSD 64779 NM_001159377 /// NM_001159378 /// NM_001159379 /// NM_001159380 /// NM_022764 /// NR_027489 /// NR_027490 /// XM_005256099 /// XM_005256100 /// XM_005256101 /// XM_005256103 /// XM_005256105 /// XM_005256106 /// XM_005256107 /// XM_005256112 /// XM_005256113 /// XM_006721247 /// XM_006721248 /// XM_006721249 /// XM_006721250 /// XM_006721251 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030272 // 5-formyltetrahydrofolate cyclo-ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218880_at N36408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36408 /FEA=EST /DB_XREF=gi:1157550 /DB_XREF=est:yy33f03.s1 /CLONE=IMAGE:273053 /UG=Hs.325364 hypothetical protein FLJ23306 /FL=gb:NM_024530.1 N36408 FOS-like antigen 2 FOSL2 2355 NM_005253 /// XM_005264231 /// XM_006711976 /// XM_006711977 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218881_s_at NM_024530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024530.1 /DEF=Homo sapiens hypothetical protein FLJ23306 (FLJ23306), mRNA. /FEA=mRNA /GEN=FLJ23306 /PROD=hypothetical protein FLJ23306 /DB_XREF=gi:13375679 /UG=Hs.325364 hypothetical protein FLJ23306 /FL=gb:NM_024530.1 NM_024530 FOS-like antigen 2 FOSL2 2355 NM_005253 /// XM_005264231 /// XM_006711976 /// XM_006711977 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008219 // cell death // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218882_s_at NM_006784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006784.1 /DEF=Homo sapiens WD repeat domain 3 (WDR3), mRNA. /FEA=mRNA /GEN=WDR3 /PROD=WD repeat-containing protein 3 /DB_XREF=gi:5803220 /UG=Hs.33085 WD repeat domain 3 /FL=gb:AF083217.1 gb:NM_006784.1 NM_006784 WD repeat domain 3 WDR3 10885 NM_006784 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218883_s_at NM_024629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024629.1 /DEF=Homo sapiens hypothetical protein FLJ23468 (FLJ23468), mRNA. /FEA=mRNA /GEN=FLJ23468 /PROD=hypothetical protein FLJ23468 /DB_XREF=gi:13375855 /UG=Hs.38178 hypothetical protein FLJ23468 /FL=gb:NM_024629.1 NM_024629 centromere protein U CENPU 79682 NM_024629 /// NR_104593 /// XM_005263218 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from electronic annotation 218884_s_at NM_021927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021927.1 /DEF=Homo sapiens hypothetical protein FLJ13220 (FLJ13220), mRNA. /FEA=mRNA /GEN=FLJ13220 /PROD=hypothetical protein FLJ13220 /DB_XREF=gi:11345459 /UG=Hs.41127 hypothetical protein FLJ13220 /FL=gb:NM_021927.1 NM_021927 GUF1 GTPase homolog (S. cerevisiae) GUF1 60558 NM_021927 /// XM_005248122 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation 218885_s_at NM_024642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024642.1 /DEF=Homo sapiens hypothetical protein FLJ21212 (FLJ21212), mRNA. /FEA=mRNA /GEN=FLJ21212 /PROD=hypothetical protein FLJ21212 /DB_XREF=gi:13375880 /UG=Hs.47099 hypothetical protein FLJ21212 /FL=gb:NM_024642.1 NM_024642 polypeptide N-acetylgalactosaminyltransferase 12 GALNT12 79695 NM_024642 /// XM_006717287 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218886_at NM_017906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017906.1 /DEF=Homo sapiens hypothetical protein FLJ20624 (FLJ20624), mRNA. /FEA=mRNA /GEN=FLJ20624 /PROD=hypothetical protein FLJ20624 /DB_XREF=gi:8923576 /UG=Hs.52256 hypothetical protein FLJ20624 /FL=gb:NM_017906.1 NM_017906 PAK1 interacting protein 1 PAK1IP1 55003 NM_017906 /// XM_005249204 /// XM_006715129 0009968 // negative regulation of signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 218887_at NM_015950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015950.1 /DEF=Homo sapiens CGI-22 protein (LOC51069), mRNA. /FEA=mRNA /GEN=LOC51069 /PROD=CGI-22 protein /DB_XREF=gi:7705713 /UG=Hs.55041 CGI-22 protein /FL=gb:AF132956.1 gb:NM_015950.1 NM_015950 mitochondrial ribosomal protein L2 MRPL2 51069 NM_015950 /// XM_005249161 /// XM_005249162 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218888_s_at NM_018092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018092.1 /DEF=Homo sapiens hypothetical protein FLJ10430 (FLJ10430), mRNA. /FEA=mRNA /GEN=FLJ10430 /PROD=hypothetical protein FLJ10430 /DB_XREF=gi:8922419 /UG=Hs.6823 hypothetical protein FLJ10430 /FL=gb:NM_018092.1 NM_018092 neuropilin (NRP) and tolloid (TLL)-like 2 NETO2 81831 NM_001201477 /// NM_018092 /// XM_006721289 /// XM_006721290 /// XM_006721291 /// XM_006721292 2000312 // regulation of kainate selective glutamate receptor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032983 // kainate selective glutamate receptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218889_at NM_022451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022451.1 /DEF=Homo sapiens hypothetical protein FLJ12820 (FLJ12820), mRNA. /FEA=mRNA /GEN=FLJ12820 /PROD=hypothetical protein FLJ12820 /DB_XREF=gi:11967984 /UG=Hs.74899 hypothetical protein FLJ12820 /FL=gb:NM_022451.1 NM_022451 nucleolar complex associated 3 homolog (S. cerevisiae) NOC3L 64318 NM_022451 /// XM_005270048 0045444 // fat cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218890_x_at NM_016622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016622.1 /DEF=Homo sapiens hypothetical protein (LOC51318), mRNA. /FEA=mRNA /GEN=LOC51318 /PROD=hypothetical protein /DB_XREF=gi:7706161 /UG=Hs.93814 hypothetical protein /FL=gb:AF208849.1 gb:NM_016622.1 NM_016622 mitochondrial ribosomal protein L35 MRPL35 51318 NM_016622 /// NM_145644 /// XM_005264361 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 218891_at NM_024541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024541.1 /DEF=Homo sapiens hypothetical protein FLJ13114 (FLJ13114), mRNA. /FEA=mRNA /GEN=FLJ13114 /PROD=hypothetical protein FLJ13114 /DB_XREF=gi:13375700 /UG=Hs.9444 hypothetical protein FLJ13114 /FL=gb:NM_024541.1 NM_024541 chromosome 10 open reading frame 76 C10orf76 79591 NM_024541 /// XM_006717969 /// XR_246104 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 218892_at NM_024542 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024542.1 /DEF=Homo sapiens hypothetical protein FLJ11790 (FLJ11790), mRNA. /FEA=mRNA /GEN=FLJ11790 /PROD=hypothetical protein FLJ11790 /DB_XREF=gi:13375702 /UG=Hs.9658 hypothetical protein FLJ11790 /FL=gb:NM_024542.1 NM_024542 dachsous cadherin-related 1 DCHS1 8642 NM_003737 /// NM_024542 /// XM_005253207 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0035329 // hippo signaling // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 218893_at NM_024710 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024710.1 /DEF=Homo sapiens hypothetical protein FLJ23469 (FLJ23469), mRNA. /FEA=mRNA /GEN=FLJ23469 /PROD=hypothetical protein FLJ23469 /DB_XREF=gi:13376006 /UG=Hs.103833 hypothetical protein FLJ23469 /FL=gb:NM_024710.1 NM_024710 isochorismatase domain containing 2 ISOC2 79763 NM_001136201 /// NM_001136202 /// NM_024710 /// XM_005259265 0008152 // metabolic process // inferred from electronic annotation /// 0031648 // protein destabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218894_s_at NM_018048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018048.1 /DEF=Homo sapiens hypothetical protein FLJ10292 (FLJ10292), mRNA. /FEA=mRNA /GEN=FLJ10292 /PROD=hypothetical protein FLJ10292 /DB_XREF=gi:8922330 /UG=Hs.104650 hypothetical protein FLJ10292 /FL=gb:NM_018048.1 gb:AF165518.1 NM_018048 mago-nashi homolog B (Drosophila) MAGOHB 55110 NM_018048 /// XM_005253402 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218895_at NM_022078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022078.1 /DEF=Homo sapiens hypothetical protein FLJ12455 (FLJ12455), mRNA. /FEA=mRNA /GEN=FLJ12455 /PROD=hypothetical protein FLJ12455 /DB_XREF=gi:11545792 /UG=Hs.10903 hypothetical protein FLJ12455 /FL=gb:NM_022078.1 NM_022078 G patch domain containing 3 GPATCH3 63906 NM_022078 0003676 // nucleic acid binding // inferred from electronic annotation 218896_s_at NM_018553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018553.1 /DEF=Homo sapiens ELG protein (HSA277841), mRNA. /FEA=mRNA /GEN=HSA277841 /PROD=ELG protein /DB_XREF=gi:8923770 /UG=Hs.120963 ELG protein /FL=gb:NM_018553.1 NM_018553 chromosome 17 open reading frame 85 C17orf85 55421 NM_001114118 /// NM_018553 /// XM_005256717 /// XM_006721556 /// XR_429819 0000166 // nucleotide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218897_at NM_030577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030577.1 /DEF=Homo sapiens hypothetical protein MGC10993 (MGC10993), mRNA. /FEA=mRNA /GEN=MGC10993 /PROD=hypothetical protein MGC10993 /DB_XREF=gi:13386491 /UG=Hs.12199 hypothetical protein MGC10993 /FL=gb:BC004404.1 gb:NM_030577.1 NM_030577 transmembrane protein 177 TMEM177 80775 NM_001105198 /// NM_001105199 /// NM_030577 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218898_at NM_024792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024792.1 /DEF=Homo sapiens hypothetical protein FLJ22282 (FLJ22282), mRNA. /FEA=mRNA /GEN=FLJ22282 /PROD=hypothetical protein FLJ22282 /DB_XREF=gi:13376161 /UG=Hs.154396 hypothetical protein FLJ22282 /FL=gb:NM_024792.1 NM_024792 family with sequence similarity 57, member A FAM57A 79850 NM_024792 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218899_s_at NM_024812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024812.1 /DEF=Homo sapiens hypothetical protein FLJ12015 (FLJ12015), mRNA. /FEA=mRNA /GEN=FLJ12015 /PROD=hypothetical protein FLJ12015 /DB_XREF=gi:13376199 /UG=Hs.169395 hypothetical protein FLJ12015 /FL=gb:NM_024812.1 NM_024812 brain and acute leukemia, cytoplasmic BAALC 79870 NM_001024372 /// NM_024812 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 218900_at NM_020184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020184.1 /DEF=Homo sapiens ancient conserved domain protein 4 (LOC56939), mRNA. /FEA=mRNA /GEN=LOC56939 /PROD=ancient conserved domain protein 4 /DB_XREF=gi:9910369 /UG=Hs.175043 ancient conserved domain protein 4 /FL=gb:AF202777.1 gb:NM_020184.1 NM_020184 cyclin M4 CNNM4 26504 NM_020184 /// XM_005263914 /// XM_005263915 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030554 // adenyl nucleotide binding // inferred from electronic annotation 218901_at NM_020353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020353.1 /DEF=Homo sapiens phospholipid scramblase 4 (LOC57088), mRNA. /FEA=mRNA /GEN=LOC57088 /PROD=phospholipid scramblase 4 /DB_XREF=gi:9966818 /UG=Hs.182538 phospholipid scramblase 4 /FL=gb:AF199023.1 gb:NM_020353.1 NM_020353 phospholipid scramblase 4 PLSCR4 57088 NM_001128304 /// NM_001128305 /// NM_001128306 /// NM_001177304 /// NM_020353 /// XM_005247654 /// XM_005247655 0007596 // blood coagulation // non-traceable author statement /// 0017121 // phospholipid scrambling // non-traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0017128 // phospholipid scramblase activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0042609 // CD4 receptor binding // inferred from physical interaction 218902_at NM_017617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017617.1 /DEF=Homo sapiens hypothetical protein FLJ20005 (FLJ20005), mRNA. /FEA=mRNA /GEN=FLJ20005 /PROD=hypothetical protein FLJ20005 /DB_XREF=gi:8923012 /UG=Hs.184634 hypothetical protein FLJ20005 /FL=gb:NM_017617.1 NM_017617 notch 1 NOTCH1 4851 NM_017617 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003157 // endocardium development // inferred from sequence or structural similarity /// 0003160 // endocardium morphogenesis // inferred from sequence or structural similarity /// 0003162 // atrioventricular node development // inferred from electronic annotation /// 0003169 // coronary vein morphogenesis // inferred from sequence or structural similarity /// 0003180 // aortic valve morphogenesis // inferred from mutant phenotype /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003192 // mitral valve formation // inferred from mutant phenotype /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003207 // cardiac chamber formation // inferred from sequence or structural similarity /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003209 // cardiac atrium morphogenesis // inferred from sequence or structural similarity /// 0003213 // cardiac right atrium morphogenesis // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003219 // cardiac right ventricle formation // inferred from electronic annotation /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from sequence or structural similarity /// 0003241 // growth involved in heart morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0003270 // Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0003273 // cell migration involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003344 // pericardium morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // non-traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007386 // compartment pattern specification // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007440 // foregut morphogenesis // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008544 // epidermis development // inferred from electronic annotation /// 0009912 // auditory receptor cell fate commitment // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0010832 // negative regulation of myotube differentiation // inferred from sequence or structural similarity /// 0014031 // mesenchymal cell development // inferred from sequence or structural similarity /// 0014807 // regulation of somitogenesis // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030513 // positive regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035148 // tube formation // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0042640 // anagen // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from mutant phenotype /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060768 // regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0060843 // venous endothelial cell differentiation // inferred from sequence or structural similarity /// 0060948 // cardiac vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0060956 // endocardial cell differentiation // inferred from sequence or structural similarity /// 0060979 // vasculogenesis involved in coronary vascular morphogenesis // inferred from sequence or structural similarity /// 0060982 // coronary artery morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred from mutant phenotype /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from sequence or structural similarity /// 0070986 // left/right axis specification // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from direct assay /// 0072017 // distal tubule development // inferred from electronic annotation /// 0072044 // collecting duct development // inferred from electronic annotation /// 0072144 // glomerular mesangial cell development // inferred from electronic annotation /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 1901201 // regulation of extracellular matrix assembly // inferred from sequence or structural similarity /// 1902263 // apoptotic process involved in embryonic digit morphogenesis // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from sequence or structural similarity /// 2001027 // negative regulation of endothelial cell chemotaxis // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0004872 // receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218903_s_at NM_024068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024068.1 /DEF=Homo sapiens hypothetical protein MGC2731 (MGC2731), mRNA. /FEA=mRNA /GEN=MGC2731 /PROD=hypothetical protein MGC2731 /DB_XREF=gi:13129047 /UG=Hs.240170 hypothetical protein MGC2731 /FL=gb:BC001079.1 gb:NM_024068.1 NM_024068 nucleic acid binding protein 2 NABP2 79035 NM_024068 /// XM_005269146 /// XM_005269147 /// XM_005269148 /// XM_005269149 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070876 // SOSS complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218904_s_at NM_017998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017998.1 /DEF=Homo sapiens hypothetical protein FLJ10110 (FLJ10110), mRNA. /FEA=mRNA /GEN=FLJ10110 /PROD=hypothetical protein FLJ10110 /DB_XREF=gi:8922232 /UG=Hs.264363 hypothetical protein FLJ10110 /FL=gb:NM_017998.1 NM_017998 chromosome 9 open reading frame 40 C9orf40 55071 NM_017998 218905_at NM_017864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017864.1 /DEF=Homo sapiens hypothetical protein FLJ20530 (FLJ20530), mRNA. /FEA=mRNA /GEN=FLJ20530 /PROD=hypothetical protein FLJ20530 /DB_XREF=gi:8923495 /UG=Hs.279521 hypothetical protein FLJ20530 /FL=gb:NM_017864.1 NM_017864 integrator complex subunit 8 INTS8 55656 NM_017864 /// NR_073444 /// NR_073445 /// XM_006716602 /// XM_006716603 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218906_x_at NM_022822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022822.1 /DEF=Homo sapiens hypothetical protein FLJ12387 similar to kinesin light chain (FLJ12387), mRNA. /FEA=mRNA /GEN=FLJ12387 /PROD=hypothetical protein FLJ12387 similar to kinesinlight chain /DB_XREF=gi:12383061 /UG=Hs.280792 hypothetical protein FLJ12387 similar to kinesin light chain /FL=gb:AL136864.1 gb:NM_022822.1 NM_022822 kinesin light chain 2 KLC2 64837 NM_001134774 /// NM_001134775 /// NM_001134776 /// NM_022822 /// XM_005274182 /// XM_005274183 /// XM_005274184 /// XM_006718665 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016938 // kinesin I complex // non-traceable author statement /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from sequence or structural similarity 218907_s_at NM_023942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023942.1 /DEF=Homo sapiens hypothetical protein MGC3036 (MGC3036), mRNA. /FEA=mRNA /GEN=MGC3036 /PROD=hypothetical protein MGC3036 /DB_XREF=gi:13027615 /UG=Hs.284135 hypothetical protein MGC3036 /FL=gb:BC001354.1 gb:NM_023942.1 NM_023942 leucine rich repeat containing 61 LRRC61 65999 NM_001142928 /// NM_023942 /// XM_006716095 0005515 // protein binding // inferred from electronic annotation 218908_at NM_024083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024083.1 /DEF=Homo sapiens ASPL protein (ASPSCR1), mRNA. /FEA=mRNA /GEN=ASPSCR1 /PROD=ASPL protein /DB_XREF=gi:13129077 /UG=Hs.298351 alveolar soft part sarcoma chromosome region, candidate 1 /FL=gb:AF324219.2 gb:NM_024083.1 NM_024083 alveolar soft part sarcoma chromosome region, candidate 1 ASPSCR1 79058 NM_001251888 /// NM_024083 /// NR_045351 0006886 // intracellular protein transport // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218909_at NM_012424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012424.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 52kD, polypeptide 1 (RPS6KC1), mRNA. /FEA=mRNA /GEN=RPS6KC1 /PROD=ribosomal protein S6 kinase, 52kD, polypeptide1 /DB_XREF=gi:6912635 /UG=Hs.30352 ribosomal protein S6 kinase, 52kD, polypeptide 1 /FL=gb:AF037447.1 gb:NM_012424.1 NM_012424 ribosomal protein S6 kinase, 52kDa, polypeptide 1 RPS6KC1 26750 NM_001136138 /// NM_001287218 /// NM_001287219 /// NM_001287220 /// NM_001287221 /// NM_012424 /// XM_005273095 /// XM_005273096 /// XM_005273098 /// XM_006711272 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 218910_at NM_018075 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018075.1 /DEF=Homo sapiens hypothetical protein FLJ10375 (FLJ10375), mRNA. /FEA=mRNA /GEN=FLJ10375 /PROD=hypothetical protein FLJ10375 /DB_XREF=gi:8922383 /UG=Hs.319088 hypothetical protein FLJ10375 /FL=gb:NM_018075.1 NM_018075 anoctamin 10 ANO10 55129 NM_001204831 /// NM_001204832 /// NM_001204833 /// NM_001204834 /// NM_018075 /// XM_005265265 0006812 // cation transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005227 // calcium activated cation channel activity // inferred from direct assay /// 0005229 // intracellular calcium activated chloride channel activity // inferred from direct assay 218911_at NM_006530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006530.1 /DEF=Homo sapiens glioma-amplified sequence-41 (GAS41), mRNA. /FEA=mRNA /GEN=GAS41 /PROD=glioma-amplified sequence-41 /DB_XREF=gi:5729837 /UG=Hs.4029 glioma-amplified sequence-41 /FL=gb:BC000994.2 gb:U61384.1 gb:NM_006530.1 NM_006530 YEATS domain containing 4 YEATS4 8089 NM_006530 /// XM_005269163 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016363 // nuclear matrix // non-traceable author statement /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 218912_at NM_024523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024523.1 /DEF=Homo sapiens hypothetical protein FLJ22035 (FLJ22035), mRNA. /FEA=mRNA /GEN=FLJ22035 /PROD=hypothetical protein FLJ22035 /DB_XREF=gi:13375665 /UG=Hs.4783 hypothetical protein FLJ22035 /FL=gb:NM_024523.1 NM_024523 GRIP and coiled-coil domain containing 1 GCC1 79571 NM_024523 0000042 // protein targeting to Golgi // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218913_s_at NM_016573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016573.1 /DEF=Homo sapiens Gem-interacting protein (LOC51291), mRNA. /FEA=mRNA /GEN=LOC51291 /PROD=Gem-interacting protein /DB_XREF=gi:7706106 /UG=Hs.49427 Gem-interacting protein /FL=gb:AF132541.1 gb:NM_016573.1 NM_016573 GEM interacting protein GMIP 51291 NM_001288998 /// NM_001288999 /// NM_016573 /// XM_005259927 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred by curator /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218914_at NM_015997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015997.1 /DEF=Homo sapiens CGI-41 protein (LOC51093), mRNA. /FEA=mRNA /GEN=LOC51093 /PROD=CGI-41 protein /DB_XREF=gi:7705758 /UG=Hs.5056 CGI-41 protein /FL=gb:AF151800.1 gb:NM_015997.1 NM_015997 ribosomal RNA adenine dimethylase domain containing 1 RRNAD1 51093 NM_001142560 /// NM_015997 /// XM_005245234 /// XM_005245235 /// XM_005245236 /// XM_005245237 /// XR_426777 /// XR_426778 0000154 // rRNA modification // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation 218915_at NM_016418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016418.1 /DEF=Homo sapiens clone FLB5214 (LOC51219), mRNA. /FEA=mRNA /GEN=LOC51219 /PROD=clone FLB5214 /DB_XREF=gi:9994194 /UG=Hs.5486 clone FLB5214 /FL=gb:AF113694.1 gb:NM_016418.1 NM_016418 neurofibromin 2 (merlin) NF2 4771 NM_000268 /// NM_016418 /// NM_181825 /// NM_181826 /// NM_181827 /// NM_181828 /// NM_181829 /// NM_181830 /// NM_181831 /// NM_181832 /// NM_181833 /// NM_181834 /// NM_181835 0001707 // mesoderm formation // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // inferred from mutant phenotype /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // traceable author statement /// 0035330 // regulation of hippo signaling // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 218916_at NM_024671 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024671.1 /DEF=Homo sapiens hypothetical protein FLJ23436 (FLJ23436), mRNA. /FEA=mRNA /GEN=FLJ23436 /PROD=hypothetical protein FLJ23436 /DB_XREF=gi:13375931 /UG=Hs.85658 hypothetical protein FLJ23436 /FL=gb:NM_024671.1 NM_024671 zinc finger protein 747 /// zinc finger protein 768 ZNF747 /// ZNF768 65988 /// 79724 NM_023931 /// NM_024671 /// XM_005255509 /// XM_005255510 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218917_s_at NM_018450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018450.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM029 (BM029), mRNA. /FEA=mRNA /GEN=BM029 /PROD=uncharacterized bone marrow protein BM029 /DB_XREF=gi:8922086 /UG=Hs.8740 uncharacterized bone marrow protein BM029 /FL=gb:AF217506.1 gb:NM_018450.1 NM_018450 AT rich interactive domain 1A (SWI-like) ARID1A 8289 NM_006015 /// NM_018450 /// NM_139135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003205 // cardiac chamber development // inferred from electronic annotation /// 0003408 // optic cup formation involved in camera-type eye development // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0042766 // nucleosome mobilization // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0043044 // ATP-dependent chromatin remodeling // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0090544 // BAF-type complex // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from electronic annotation 218918_at NM_020379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020379.1 /DEF=Homo sapiens 1,2-alpha-mannosidase IC (HMIC), mRNA. /FEA=mRNA /GEN=HMIC /PROD=1,2-alpha-mannosidase IC /DB_XREF=gi:9966902 /UG=Hs.8910 1,2-alpha-mannosidase IC /FL=gb:AF261655.1 gb:NM_020379.1 NM_020379 mannosidase, alpha, class 1C, member 1 MAN1C1 57134 NM_001289010 /// NM_020379 /// XM_005245945 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // traceable author statement 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 218919_at NM_024699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024699.1 /DEF=Homo sapiens hypothetical protein FLJ14007 (FLJ14007), mRNA. /FEA=mRNA /GEN=FLJ14007 /PROD=hypothetical protein FLJ14007 /DB_XREF=gi:13375984 /UG=Hs.99519 hypothetical protein FLJ14007 /FL=gb:NM_024699.1 NM_024699 zinc finger, AN1-type domain 1 ZFAND1 79752 NM_001170796 /// NM_001170797 /// NM_024699 /// NR_033193 /// NR_033194 /// NR_033195 /// NR_033196 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218920_at NM_019057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019057.1 /DEF=Homo sapiens hypothetical protein (FLJ10404), mRNA. /FEA=mRNA /GEN=FLJ10404 /PROD=hypothetical protein /DB_XREF=gi:9506606 /UG=Hs.111279 hypothetical protein /FL=gb:NM_019057.1 NM_019057 family with sequence similarity 193, member B FAM193B 54540 NM_001190946 /// NM_019057 /// NR_024019 /// XM_006714875 /// XM_006714876 /// XM_006714877 /// XM_006714878 /// XM_006714879 /// XM_006714880 /// XM_006714881 /// XM_006714882 /// XM_006714883 /// XM_006714884 /// XM_006714885 /// XM_006714886 /// XR_427804 /// XR_427805 /// XR_427806 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 218921_at NM_021805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021805.1 /DEF=Homo sapiens single Ig IL-1R-related molecule (SIGIRR), mRNA. /FEA=mRNA /GEN=SIGIRR /PROD=single Ig IL-1R-related molecule /DB_XREF=gi:11141876 /UG=Hs.11809 single Ig IL-1R-related molecule /FL=gb:NM_021805.1 gb:BC003591.1 NM_021805 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain SIGIRR 59307 NM_001135053 /// NM_001135054 /// NM_021805 /// XM_005253044 /// XM_005253045 /// XM_005253046 /// XM_005253047 /// XM_005253048 /// XR_242815 /// XR_242816 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045079 // negative regulation of chemokine biosynthetic process // inferred from sequence or structural similarity 0016020 // membrane // inferred from mutant phenotype /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218922_s_at NM_024552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024552.1 /DEF=Homo sapiens hypothetical protein FLJ12089 (FLJ12089), mRNA. /FEA=mRNA /GEN=FLJ12089 /PROD=hypothetical protein FLJ12089 /DB_XREF=gi:13375716 /UG=Hs.11896 hypothetical protein FLJ12089 /FL=gb:NM_024552.1 NM_024552 ceramide synthase 4 CERS4 79603 NM_024552 /// XM_006722887 /// XM_006722888 /// XM_006722889 /// XM_006722890 /// XM_006722891 /// XM_006722892 /// XM_006722893 /// XM_006722894 /// XM_006722895 /// XM_006722896 /// XM_006722897 /// XM_006722898 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0050291 // sphingosine N-acyltransferase activity // inferred from electronic annotation 218923_at AW304174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW304174 /FEA=EST /DB_XREF=gi:6713863 /DB_XREF=est:xv61d01.x1 /CLONE=IMAGE:2817601 /UG=Hs.135578 chitobiase, di-N-acetyl- /FL=gb:M95767.1 gb:NM_004388.1 AW304174 chitobiase, di-N-acetyl- CTBS 1486 NM_004388 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 218924_s_at NM_004388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004388.1 /DEF=Homo sapiens chitobiase, di-N-acetyl- (CTBS), mRNA. /FEA=mRNA /GEN=CTBS /PROD=chitobiase, di-N-acetyl- /DB_XREF=gi:4758091 /UG=Hs.135578 chitobiase, di-N-acetyl- /FL=gb:M95767.1 gb:NM_004388.1 NM_004388 chitobiase, di-N-acetyl- CTBS 1486 NM_004388 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 218925_s_at NM_022761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022761.1 /DEF=Homo sapiens hypothetical protein FLJ23499 (FLJ23499), mRNA. /FEA=mRNA /GEN=FLJ23499 /PROD=hypothetical protein FLJ23499 /DB_XREF=gi:12232430 /UG=Hs.17546 hypothetical protein FLJ23499 /FL=gb:NM_022761.1 NM_022761 chromosome 11 open reading frame 1 C11orf1 64776 NM_022761 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 218926_at NM_018657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018657.2 /DEF=Homo sapiens myoneurin (LOC55892), mRNA. /FEA=mRNA /GEN=LOC55892 /PROD=myoneurin /DB_XREF=gi:13569844 /UG=Hs.22934 myoneurin /FL=gb:AF148848.2 gb:NM_018657.2 gb:AF076249.1 NM_018657 myoneurin MYNN 55892 NM_001185118 /// NM_001185119 /// NM_018657 /// NR_033702 /// NR_033703 /// XM_005247621 /// XM_005247622 /// XM_005247624 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218927_s_at NM_018641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018641.1 /DEF=Homo sapiens chondroitin 4-O-sulfotransferase 2 (C4S-2), mRNA. /FEA=mRNA /GEN=C4S-2 /PROD=chondroitin 4-O-sulfotransferase 2 /DB_XREF=gi:8922111 /UG=Hs.25204 chondroitin 4-O-sulfotransferase 2 /FL=gb:BC002918.1 gb:NM_018641.1 gb:AF239822.1 NM_018641 carbohydrate (chondroitin 4) sulfotransferase 12 CHST12 55501 NM_001243794 /// NM_001243795 /// NM_018641 0005975 // carbohydrate metabolic process // traceable author statement /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047756 // chondroitin 4-sulfotransferase activity // inferred from direct assay /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // non-traceable author statement 218928_s_at NM_018964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018964.1 /DEF=Homo sapiens solute carrier family 37 (glycerol-3-phosphate transporter), member 1 (SLC37A1), mRNA. /FEA=mRNA /GEN=SLC37A1 /PROD=solute carrier family 37 (glycerol-3-phosphatetransporter), member 1 /DB_XREF=gi:9507120 /UG=Hs.301871 solute carrier family 37 (glycerol-3-phosphate transporter), member 1 /FL=gb:NM_018964.1 NM_018964 solute carrier family 37 (glucose-6-phosphate transporter), member 1 SLC37A1 54020 NM_018964 /// XM_005261139 /// XM_005261140 /// XM_005261141 /// XM_005261142 /// XM_006724014 /// XM_006724015 /// XM_006724016 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 218929_at NM_017632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017632.1 /DEF=Homo sapiens hypothetical protein FLJ20036 (FLJ20036), mRNA. /FEA=mRNA /GEN=FLJ20036 /PROD=hypothetical protein FLJ20036 /DB_XREF=gi:8923039 /UG=Hs.32922 hypothetical protein FLJ20036 /FL=gb:NM_017632.1 NM_017632 CDKN2A interacting protein CDKN2AIP 55602 NM_017632 /// XM_005263118 0009967 // positive regulation of signal transduction // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype 0001652 // granular component // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218930_s_at NM_018374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018374.1 /DEF=Homo sapiens hypothetical protein FLJ11273 (FLJ11273), mRNA. /FEA=mRNA /GEN=FLJ11273 /PROD=hypothetical protein FLJ11273 /DB_XREF=gi:8922965 /UG=Hs.3542 hypothetical protein FLJ11273 /FL=gb:NM_018374.1 NM_018374 transmembrane protein 106B TMEM106B 54664 NM_001134232 /// NM_018374 /// XM_005249789 /// XM_006715749 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032418 // lysosome localization // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218931_at NM_022449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022449.1 /DEF=Homo sapiens hypothetical protein FLJ12538 similar to ras-related protein RAB17 (FLJ12538), mRNA. /FEA=mRNA /GEN=FLJ12538 /PROD=hypothetical protein FLJ12538 similar toras-related protein RAB17 /DB_XREF=gi:11967980 /UG=Hs.44278 hypothetical protein FLJ12538 similar to ras-related protein RAB17 /FL=gb:NM_022449.1 gb:AL136645.1 NM_022449 RAB17, member RAS oncogene family RAB17 64284 NM_022449 /// NR_033308 /// XM_006712687 /// XM_006712688 /// XM_006712689 0002415 // immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032401 // establishment of melanosome localization // inferred from sequence or structural similarity /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from sequence or structural similarity /// 0045056 // transcytosis // inferred from sequence or structural similarity /// 0046847 // filopodium assembly // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from sequence or structural similarity /// 0051489 // regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 218932_at NM_017953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017953.1 /DEF=Homo sapiens hypothetical protein FLJ20729 (FLJ20729), mRNA. /FEA=mRNA /GEN=FLJ20729 /PROD=hypothetical protein FLJ20729 /DB_XREF=gi:8923654 /UG=Hs.5111 hypothetical protein FLJ20729 /FL=gb:AL442074.1 gb:NM_017953.1 NM_017953 zinc finger, HIT-type containing 6 ZNHIT6 54680 NM_001170670 /// NM_017953 /// XM_006710703 0000492 // box C/D snoRNP assembly // inferred from mutant phenotype /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218933_at NM_024063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024063.1 /DEF=Homo sapiens hypothetical protein MGC5347 (MGC5347), mRNA. /FEA=mRNA /GEN=MGC5347 /PROD=hypothetical protein MGC5347 /DB_XREF=gi:13129039 /UG=Hs.5555 hypothetical protein MGC5347 /FL=gb:BC000981.2 gb:NM_024063.1 NM_024063 spermatogenesis associated 5-like 1 SPATA5L1 79029 NM_024063 /// NR_027635 /// XM_005254657 /// XR_243126 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0070842 // aggresome assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from electronic annotation 218934_s_at NM_014424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014424.1 /DEF=Homo sapiens heat shock 27kD protein family, member 7 (cardiovascular) (HSPB7), mRNA. /FEA=mRNA /GEN=HSPB7 /PROD=heat shock 27kD protein family, member 7(cardiovascular) /DB_XREF=gi:7657201 /UG=Hs.56874 heat shock 27kD protein family, member 7 (cardiovascular) /FL=gb:AF155908.1 gb:NM_014424.1 NM_014424 heat shock 27kDa protein family, member 7 (cardiovascular) HSPB7 27129 NM_014424 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0031005 // filamin binding // inferred from electronic annotation 218935_at NM_014600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014600.1 /DEF=Homo sapiens EH-domain containing 3 (EHD3), mRNA. /FEA=mRNA /GEN=EHD3 /PROD=EH-domain containing 3 /DB_XREF=gi:7657055 /UG=Hs.87125 EH-domain containing 3 /FL=gb:AF214736.1 gb:AF181264.1 gb:NM_014600.1 NM_014600 EH-domain containing 3 EHD3 30845 NM_014600 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0072661 // protein targeting to plasma membrane // inferred from genetic interaction /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from genetic interaction 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218936_s_at NM_014167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014167.1 /DEF=Homo sapiens HSPC128 protein (HSPC128), mRNA. /FEA=mRNA /GEN=HSPC128 /PROD=HSPC128 protein /DB_XREF=gi:7661789 /UG=Hs.90527 HSPC128 protein /FL=gb:AF213377.1 gb:AF161477.1 gb:NM_014167.1 NM_014167 coiled-coil domain containing 59 CCDC59 29080 NM_014167 /// NR_033192 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218937_at NM_017810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017810.1 /DEF=Homo sapiens hypothetical protein FLJ20417 (FLJ20417), mRNA. /FEA=mRNA /GEN=FLJ20417 /PROD=hypothetical protein FLJ20417 /DB_XREF=gi:8923385 /UG=Hs.10710 hypothetical protein FLJ20417 /FL=gb:NM_017810.1 NM_017810 zinc finger and SCAN domain containing 32 ZSCAN32 54925 NM_001284527 /// NM_001284528 /// NM_001284529 /// NM_017810 /// XM_005255402 /// XM_005255403 /// XM_005255404 /// XM_005255406 /// XM_006720901 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218938_at NM_024326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024326.1 /DEF=Homo sapiens hypothetical protein MGC11279 (MGC11279), mRNA. /FEA=mRNA /GEN=MGC11279 /PROD=hypothetical protein MGC11279 /DB_XREF=gi:13236572 /UG=Hs.10915 hypothetical protein MGC11279 /FL=gb:BC002912.1 gb:NM_024326.1 NM_024326 F-box and leucine-rich repeat protein 15 FBXL15 79176 NM_024326 /// XM_005270149 /// XM_005270150 /// XM_005270151 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 218939_at NM_012318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012318.1 /DEF=Homo sapiens leucine zipper-EF-hand containing transmembrane protein 1 (LETM1), mRNA. /FEA=mRNA /GEN=LETM1 /PROD=leucine zipper-EF-hand containing transmembraneprotein 1 /DB_XREF=gi:6912481 /UG=Hs.120165 leucine zipper-EF-hand containing transmembrane protein 1 /FL=gb:AF061025.1 gb:NM_012318.1 NM_012318 leucine zipper-EF-hand containing transmembrane protein 1 LETM1 3954 NM_012318 /// XM_005247970 /// XM_006713884 0042407 // cristae formation // inferred from mutant phenotype 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218940_at NM_024558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024558.1 /DEF=Homo sapiens hypothetical protein FLJ13920 (FLJ13920), mRNA. /FEA=mRNA /GEN=FLJ13920 /PROD=hypothetical protein FLJ13920 /DB_XREF=gi:13375724 /UG=Hs.13056 hypothetical protein FLJ13920 /FL=gb:NM_024558.1 NM_024558 valosin containing protein lysine (K) methyltransferase VCPKMT 79609 NM_001040662 /// NM_024558 /// NR_049738 /// NR_049739 /// XM_005268060 /// XM_005268061 /// XM_006720254 /// XR_429329 0018023 // peptidyl-lysine trimethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 218941_at NM_012164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012164.2 /DEF=Homo sapiens f-box and WD-40 domain protein 2 (FBXW2), mRNA. /FEA=mRNA /GEN=FBXW2 /PROD=f-box and WD-40 domain protein 2 /DB_XREF=gi:7549806 /UG=Hs.13755 f-box and WD-40 domain protein 2 /FL=gb:AF176698.1 gb:NM_012164.2 NM_012164 F-box and WD repeat domain containing 2 FBXW2 26190 NM_012164 /// XM_005251908 /// XM_005251910 /// XM_005251912 /// XM_005251913 /// XM_006717049 /// XM_006717050 /// XM_006717051 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0016567 // protein ubiquitination // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218942_at NM_024779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024779.1 /DEF=Homo sapiens hypothetical protein FLJ22055 (FLJ22055), mRNA. /FEA=mRNA /GEN=FLJ22055 /PROD=hypothetical protein FLJ22055 /DB_XREF=gi:13376135 /UG=Hs.144502 hypothetical protein FLJ22055 /FL=gb:NM_024779.1 NM_024779 phosphatidylinositol-5-phosphate 4-kinase, type II, gamma PIP4K2C 79837 NM_001146258 /// NM_001146259 /// NM_001146260 /// NM_024779 /// XM_005269152 /// XM_006719604 0016310 // phosphorylation // inferred from electronic annotation /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 218943_s_at NM_014314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014314.1 /DEF=Homo sapiens RNA helicase (RIG-I), mRNA. /FEA=mRNA /GEN=RIG-I /PROD=RNA helicase /DB_XREF=gi:7657515 /UG=Hs.145612 RNA helicase /FL=gb:AF038963.1 gb:NM_014314.1 NM_014314 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 DDX58 23586 NM_014314 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009597 // detection of virus // inferred from direct assay /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred from mutant phenotype /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0034344 // regulation of type III interferon production // traceable author statement /// 0039528 // cytoplasmic pattern recognition receptor signaling pathway in response to virus // traceable author statement /// 0039529 // RIG-I signaling pathway // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred by curator /// 0051607 // defense response to virus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from mutant phenotype /// 0003725 // double-stranded RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from mutant phenotype /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 218944_at NM_023078 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023078.1 /DEF=Homo sapiens hypothetical protein FLJ13852 (FLJ13852), mRNA. /FEA=mRNA /GEN=FLJ13852 /PROD=hypothetical protein FLJ13852 /DB_XREF=gi:12751492 /UG=Hs.165186 hypothetical protein FLJ13852 /FL=gb:NM_023078.1 NM_023078 pyrroline-5-carboxylate reductase-like PYCRL 65263 NM_023078 /// XM_005251029 /// XM_006725092 0006561 // proline biosynthetic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0004735 // pyrroline-5-carboxylate reductase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 218945_at NM_024109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024109.1 /DEF=Homo sapiens hypothetical protein MGC2654 (MGC2654), mRNA. /FEA=mRNA /GEN=MGC2654 /PROD=hypothetical protein MGC2654 /DB_XREF=gi:13129121 /UG=Hs.165428 hypothetical protein MGC2654 /FL=gb:BC001908.1 gb:NM_024109.1 NM_024109 methyltransferase like 22 METTL22 79091 NM_024109 /// XM_005255570 /// XM_005255571 /// XM_005255572 /// XR_243304 /// XR_243305 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 218946_at NM_015700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015700.1 /DEF=Homo sapiens HIRIP5 protein (HIRIP5), mRNA. /FEA=mRNA /GEN=HIRIP5 /PROD=HIRIP5 protein /DB_XREF=gi:7661719 /UG=Hs.17368 HIRIP5 protein; HIRA-interacting protein 5 /FL=gb:AF132967.1 gb:NM_015700.1 NM_015700 NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) NFU1 27247 NM_001002755 /// NM_001002756 /// NM_001002757 /// NM_015700 /// NR_045631 /// NR_045632 /// XM_006711988 0016226 // iron-sulfur cluster assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 218947_s_at NM_018109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018109.1 /DEF=Homo sapiens hypothetical protein FLJ10486 (FLJ10486), mRNA. /FEA=mRNA /GEN=FLJ10486 /PROD=hypothetical protein FLJ10486 /DB_XREF=gi:8922453 /UG=Hs.173946 hypothetical protein FLJ10486 /FL=gb:NM_018109.1 NM_018109 mitochondrial poly(A) polymerase MTPAP 55149 NM_018109 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0002134 // UTP binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218948_at AL136679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136679.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C1278 (from clone DKFZp564C1278); complete cds. /FEA=mRNA /GEN=DKFZp564C1278 /PROD=hypothetical protein /DB_XREF=gi:12052881 /UG=Hs.210778 hypothetical protein FLJ10989 /FL=gb:AL136679.1 gb:NM_018292.1 AL136679 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 QRSL1 55278 NM_018292 0006412 // translation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 218949_s_at NM_018292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018292.1 /DEF=Homo sapiens hypothetical protein FLJ10989 (FLJ10989), mRNA. /FEA=mRNA /GEN=FLJ10989 /PROD=hypothetical protein FLJ10989 /DB_XREF=gi:8922807 /UG=Hs.210778 hypothetical protein FLJ10989 /FL=gb:AL136679.1 gb:NM_018292.1 NM_018292 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 QRSL1 55278 NM_018292 0006412 // translation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay 218950_at NM_022481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022481.1 /DEF=Homo sapiens hypothetical protein FLJ21065 (FLJ21065), mRNA. /FEA=mRNA /GEN=FLJ21065 /PROD=hypothetical protein FLJ21065 /DB_XREF=gi:11968032 /UG=Hs.25277 hypothetical protein FLJ21065 /FL=gb:NM_022481.1 NM_022481 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 ARAP3 64411 NM_022481 /// XM_005268497 /// XM_005268498 /// XM_005268499 /// XM_005268500 /// XM_006714791 /// XM_006714792 /// XM_006714793 0007010 // cytoskeleton organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001726 // ruffle // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred by curator /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from sequence or structural similarity /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218951_s_at NM_018390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018390.1 /DEF=Homo sapiens hypothetical protein FLJ11323 (FLJ11323), mRNA. /FEA=mRNA /GEN=FLJ11323 /PROD=hypothetical protein FLJ11323 /DB_XREF=gi:8922994 /UG=Hs.25625 hypothetical protein FLJ11323 /FL=gb:NM_018390.1 NM_018390 phosphatidylinositol-specific phospholipase C, X domain containing 1 PLCXD1 55344 NM_018390 /// NR_028057 /// XM_006724444 /// XM_006724445 /// XM_006724446 /// XM_006724865 /// XM_006724866 /// XM_006724867 0006629 // lipid metabolic process // inferred from electronic annotation 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation 218952_at NM_013271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013271.1 /DEF=Homo sapiens granin-like neuroendocrine peptide precursor (SAAS), mRNA. /FEA=mRNA /GEN=SAAS /PROD=granin-like neuroendocrine peptide precursor /DB_XREF=gi:7019518 /UG=Hs.256311 granin-like neuroendocrine peptide precursor /FL=gb:BC002851.1 gb:AF181562.1 gb:NM_013271.1 NM_013271 proprotein convertase subtilisin/kexin type 1 inhibitor PCSK1N 27344 NM_013271 0002021 // response to dietary excess // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0016486 // peptide hormone processing // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement 218953_s_at NM_024028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024028.1 /DEF=Homo sapiens hypothetical protein MGC3265 (MGC3265), mRNA. /FEA=mRNA /GEN=MGC3265 /PROD=hypothetical protein MGC3265 /DB_XREF=gi:13128973 /UG=Hs.257111 hypothetical protein MGC3265 /FL=gb:BC000014.1 gb:NM_024028.1 NM_024028 prenylcysteine oxidase 1 like PCYOX1L 78991 NM_024028 /// XM_006714794 /// XM_006714795 0030328 // prenylcysteine catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0001735 // prenylcysteine oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016670 // oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor // inferred from electronic annotation 218954_s_at AF298153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF298153.1 /DEF=Homo sapiens RNA polymerase III transcription initiation factor BRFU mRNA, complete cds. /FEA=mRNA /PROD=RNA polymerase III transcription initiationfactor BRFU /DB_XREF=gi:11096174 /UG=Hs.274136 hypothetical protein FLJ11052 /FL=gb:AF298153.1 gb:AF130058.1 gb:AF206673.2 gb:NM_018310.1 AF298153 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit BRF2 55290 NM_018310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218955_at NM_018310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018310.1 /DEF=Homo sapiens hypothetical protein FLJ11052 (FLJ11052), mRNA. /FEA=mRNA /GEN=FLJ11052 /PROD=hypothetical protein FLJ11052 /DB_XREF=gi:8922843 /UG=Hs.274136 hypothetical protein FLJ11052 /FL=gb:AF298153.1 gb:AF130058.1 gb:AF206673.2 gb:NM_018310.1 NM_018310 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit BRF2 55290 NM_018310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218956_s_at NM_015545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015545.1 /DEF=Homo sapiens KIAA0632 protein (KIAA0632), mRNA. /FEA=mRNA /GEN=KIAA0632 /PROD=KIAA0632 protein /DB_XREF=gi:13357213 /UG=Hs.278317 KIAA0632 protein /FL=gb:BC003688.1 gb:NM_015545.1 NM_015545 ATP5J2-PTCD1 readthrough /// pentatricopeptide repeat domain 1 ATP5J2-PTCD1 /// PTCD1 26024 /// 100526740 NM_001198879 /// NM_015545 0008033 // tRNA processing // inferred from electronic annotation /// 0042780 // tRNA 3'-end processing // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity 0000049 // tRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 218957_s_at NM_025155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025155.1 /DEF=Homo sapiens hypothetical protein FLJ11848 (FLJ11848), mRNA. /FEA=mRNA /GEN=FLJ11848 /PROD=hypothetical protein FLJ11848 /DB_XREF=gi:13376750 /UG=Hs.289031 hypothetical protein FLJ11848 /FL=gb:NM_025155.1 NM_025155 proteasomal ATPase-associated factor 1 PAAF1 80227 NM_001267803 /// NM_001267804 /// NM_001267805 /// NM_001267806 /// NM_025155 /// XM_005274308 /// XM_005274309 /// XM_005274310 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218958_at NM_017967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017967.1 /DEF=Homo sapiens hypothetical protein FLJ20850 (FLJ20850), mRNA. /FEA=mRNA /GEN=FLJ20850 /PROD=hypothetical protein FLJ20850 /DB_XREF=gi:8923696 /UG=Hs.30783 hypothetical protein FLJ20850 /FL=gb:NM_017967.1 NM_017967 chromosome 19 open reading frame 60 C19orf60 55049 NM_001100418 /// NM_001100419 /// NM_017967 /// XM_005259977 0005515 // protein binding // inferred from physical interaction 218959_at NM_017409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017409.1 /DEF=Homo sapiens homeo box C10 (HOXC10), mRNA. /FEA=mRNA /GEN=HOXC10 /PROD=homeo box C10 /DB_XREF=gi:8393550 /UG=Hs.44276 homeo box C10 /FL=gb:BC001293.1 gb:AF255675.1 gb:NM_017409.1 NM_017409 homeobox C10 HOXC10 3226 NM_017409 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0021520 // spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 218960_at NM_016425 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016425.1 /DEF=Homo sapiens transmembrane protease, serine 4 (TMPRSS4), mRNA. /FEA=mRNA /GEN=TMPRSS4 /PROD=transmembrane protease, serine 4 /DB_XREF=gi:7705976 /UG=Hs.63325 transmembrane protease, serine 4 /FL=gb:AF216312.1 gb:NM_016425.1 gb:AF179224.1 NM_016425 transmembrane protease, serine 4 TMPRSS4 56649 NM_001083947 /// NM_001173551 /// NM_001173552 /// NM_001290094 /// NM_001290096 /// NM_019894 /// NM_183247 /// NR_110734 /// XM_005271613 /// XM_005271614 /// XM_005271615 /// XM_006718883 /// XM_006718884 /// XM_006718885 0006508 // proteolysis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218961_s_at NM_007254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007254.1 /DEF=Homo sapiens polynucleotide kinase 3-phosphatase (PNKP), mRNA. /FEA=mRNA /GEN=PNKP /PROD=polynucleotide kinase 3-phosphatase /DB_XREF=gi:6005835 /UG=Hs.78016 polynucleotide kinase 3-phosphatase /FL=gb:AF120499.1 gb:AF125807.1 gb:AF126486.1 gb:NM_007254.1 NM_007254 polynucleotide kinase 3'-phosphatase PNKP 11284 NM_007254 0000718 // nucleotide-excision repair, DNA damage removal // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // non-traceable author statement /// 0006281 // DNA repair // inferred from genetic interaction /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009314 // response to radiation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0042769 // DNA damage response, detection of DNA damage // non-traceable author statement /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // non-traceable author statement /// 0098506 // polynucleotide 3' dephosphorylation // inferred from direct assay /// 0098506 // polynucleotide 3' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // non-traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004519 // endonuclease activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // non-traceable author statement /// 0019201 // nucleotide kinase activity // inferred from direct assay /// 0046403 // polynucleotide 3'-phosphatase activity // inferred from direct assay /// 0046404 // ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity // inferred from direct assay 218962_s_at NM_022484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022484.1 /DEF=Homo sapiens hypothetical protein FLJ13576 (FLJ13576), mRNA. /FEA=mRNA /GEN=FLJ13576 /PROD=hypothetical protein FLJ13576 /DB_XREF=gi:11968036 /UG=Hs.79353 hypothetical protein FLJ13576 /FL=gb:NM_022484.1 NM_022484 transmembrane protein 168 TMEM168 64418 NM_001287497 /// NM_022484 /// NR_109840 /// XM_005250527 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 218963_s_at NM_015515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015515.1 /DEF=Homo sapiens DKFZP434G032 protein (DKFZP434G032), mRNA. /FEA=mRNA /GEN=DKFZP434G032 /PROD=DKFZP434G032 protein /DB_XREF=gi:7661573 /UG=Hs.9029 DKFZP434G032 protein /FL=gb:AF102848.1 gb:NM_015515.1 NM_015515 keratin 23 (histone deacetylase inducible) KRT23 25984 NM_001282433 /// NM_015515 /// NM_173213 /// XM_005257200 /// XM_005277791 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 218964_at NM_006465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006465.1 /DEF=Homo sapiens dead ringer (Drosophila)-like 2 (bright and dead ringer) (DRIL2), mRNA. /FEA=mRNA /GEN=DRIL2 /PROD=dead ringer-like 2 /DB_XREF=gi:5453637 /UG=Hs.10431 dead ringer (Drosophila)-like 2 (bright and dead ringer) /FL=gb:AF116846.1 gb:NM_006465.1 NM_006465 AT rich interactive domain 3B (BRIGHT-like) ARID3B 10620 NM_006465 /// XM_005254129 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement 218965_s_at NM_022830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022830.1 /DEF=Homo sapiens hypothetical protein FLJ22347 (FLJ22347), mRNA. /FEA=mRNA /GEN=FLJ22347 /PROD=hypothetical protein FLJ22347 /DB_XREF=gi:12383073 /UG=Hs.106004 hypothetical protein FLJ22347 /FL=gb:NM_022830.1 gb:BC005013.1 NM_022830 terminal uridylyl transferase 1, U6 snRNA-specific TUT1 64852 NM_022830 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from mutant phenotype /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0004652 // polynucleotide adenylyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050265 // RNA uridylyltransferase activity // inferred from direct assay 218966_at NM_018728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018728.1 /DEF=Homo sapiens myosin 5C (MYO5C), mRNA. /FEA=mRNA /GEN=MYO5C /PROD=myosin 5C /DB_XREF=gi:9055283 /UG=Hs.111782 myosin 5C /FL=gb:AF272390.1 gb:NM_018728.1 NM_018728 myosin VC MYO5C 55930 NM_018728 /// XM_006720607 0008152 // metabolic process // inferred from electronic annotation /// 0032254 // establishment of secretory granule localization // inferred from mutant phenotype 0016459 // myosin complex // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 218967_s_at NM_030664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030664.1 /DEF=Homo sapiens phosphotriesterase related (PTER), mRNA. /FEA=mRNA /GEN=PTER /PROD=phosphotriesterase related /DB_XREF=gi:13489055 /UG=Hs.129915 phosphotriesterase related /FL=gb:AF212237.1 gb:NM_030664.1 NM_030664 phosphotriesterase related PTER 9317 NM_001001484 /// NM_001261836 /// NM_001261837 /// NM_001261838 /// NM_030664 /// XM_006717537 /// XM_006717538 0009056 // catabolic process // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218968_s_at NM_018197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018197.1 /DEF=Homo sapiens hypothetical protein FLJ10734 (FLJ10734), mRNA. /FEA=mRNA /GEN=FLJ10734 /PROD=hypothetical protein FLJ10734 /DB_XREF=gi:8922626 /UG=Hs.146332 hypothetical protein FLJ10734 /FL=gb:NM_018197.1 NM_018197 ZFP64 zinc finger protein ZFP64 55734 NM_018197 /// NM_022088 /// NM_199426 /// NM_199427 /// XM_005260449 /// XM_005260450 /// XM_006723821 /// XM_006723822 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 218969_at NM_016069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016069.1 /DEF=Homo sapiens CGI-136 protein (LOC51025), mRNA. /FEA=mRNA /GEN=LOC51025 /PROD=CGI-136 protein /DB_XREF=gi:7705633 /UG=Hs.16089 CGI-136 protein /FL=gb:BC005024.1 gb:AF151894.1 gb:NM_016069.1 NM_016069 presequence translocase-associated motor 16 homolog (S. cerevisiae) PAM16 51025 NM_016069 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030150 // protein import into mitochondrial matrix // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 218970_s_at NM_015960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015960.1 /DEF=Homo sapiens CGI-32 protein (LOC51076), mRNA. /FEA=mRNA /GEN=LOC51076 /PROD=CGI-32 protein /DB_XREF=gi:7705727 /UG=Hs.16606 CGI-32 protein /FL=gb:AF132966.1 gb:NM_015960.1 NM_015960 cutC copper transporter CUTC 51076 NM_015960 0006825 // copper ion transport // non-traceable author statement /// 0051262 // protein tetramerization // inferred from physical interaction /// 0055070 // copper ion homeostasis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 218971_s_at NM_014149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014149.1 /DEF=Homo sapiens HSPC049 protein (HSPC049), mRNA. /FEA=mRNA /GEN=HSPC049 /PROD=HSPC049 protein /DB_XREF=gi:7661753 /UG=Hs.172622 HSPC049 protein /FL=gb:AF161534.1 gb:NM_014149.1 NM_014149 WD repeat domain 91 WDR91 29062 NM_014149 /// XM_005250285 /// XR_242231 /// XR_242232 0005515 // protein binding // inferred from electronic annotation 218972_at NM_018259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018259.1 /DEF=Homo sapiens hypothetical protein FLJ10890 (FLJ10890), mRNA. /FEA=mRNA /GEN=FLJ10890 /PROD=hypothetical protein FLJ10890 /DB_XREF=gi:8922741 /UG=Hs.17283 hypothetical protein FLJ10890 /FL=gb:NM_018259.1 NM_018259 tetratricopeptide repeat domain 17 TTC17 55761 NM_018259 /// XM_005253016 /// XM_005253017 /// XM_006718263 0030030 // cell projection organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from mutant phenotype /// 0044782 // cilium organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 218973_at NM_024580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024580.1 /DEF=Homo sapiens hypothetical protein FLJ13119 (FLJ13119), mRNA. /FEA=mRNA /GEN=FLJ13119 /PROD=hypothetical protein FLJ13119 /DB_XREF=gi:13375759 /UG=Hs.19348 hypothetical protein FLJ13119 /FL=gb:NM_024580.1 NM_024580 elongation factor Tu GTP binding domain containing 1 EFTUD1 79631 NM_001040610 /// NM_024580 0006184 // GTP catabolic process // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from mutant phenotype 218974_at NM_018013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018013.1 /DEF=Homo sapiens hypothetical protein FLJ10159 (FLJ10159), mRNA. /FEA=mRNA /GEN=FLJ10159 /PROD=hypothetical protein FLJ10159 /DB_XREF=gi:8922262 /UG=Hs.22505 hypothetical protein FLJ10159 /FL=gb:NM_018013.1 NM_018013 sine oculis binding protein homolog (Drosophila) SOBP 55084 NM_018013 /// XM_005267041 /// XM_005267042 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation 0032184 // SUMO polymer binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 218975_at NM_015719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015719.1 /DEF=Homo sapiens collagen, type V, alpha 3 (COL5A3), mRNA. /FEA=mRNA /GEN=COL5A3 /PROD=procollagen, type V, alpha 3 /DB_XREF=gi:7656988 /UG=Hs.235368 collagen, type V, alpha 3 /FL=gb:AF177941.1 gb:NM_015719.1 NM_015719 collagen, type V, alpha 3 COL5A3 50509 NM_015719 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0043588 // skin development // non-traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from electronic annotation 218976_at NM_021800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021800.1 /DEF=Homo sapiens J domain containing protein 1 (JDP1), mRNA. /FEA=mRNA /GEN=JDP1 /PROD=J domain containing protein 1 /DB_XREF=gi:11141870 /UG=Hs.260720 J domain containing protein 1 /FL=gb:NM_021800.1 gb:AF176012.1 NM_021800 DnaJ (Hsp40) homolog, subfamily C, member 12 DNAJC12 56521 NM_021800 /// NM_201262 218977_s_at NM_017846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017846.1 /DEF=Homo sapiens tRNA selenocysteine associated protein (SECP43), mRNA. /FEA=mRNA /GEN=SECP43 /PROD=tRNA selenocysteine associated protein /DB_XREF=gi:8923459 /UG=Hs.266935 tRNA selenocysteine associated protein /FL=gb:BC000680.1 gb:NM_017846.1 NM_017846 tRNA selenocysteine 1 associated protein 1 TRNAU1AP 54952 NM_017846 /// NR_003109 0001514 // selenocysteine incorporation // inferred from sequence or structural similarity /// 0006412 // translation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218978_s_at NM_018586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018586.1 /DEF=Homo sapiens hypothetical protein PRO1584 (PRO1584), mRNA. /FEA=mRNA /GEN=PRO1584 /PROD=hypothetical protein PRO1584 /DB_XREF=gi:8924059 /UG=Hs.283716 hypothetical protein PRO1584 /FL=gb:AF116640.1 gb:NM_018586.1 NM_018586 solute carrier family 25 (mitochondrial iron transporter), member 37 SLC25A37 51312 NM_016612 /// XM_005273526 /// XM_006716352 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048250 // mitochondrial iron ion transport // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation 218979_at NM_024945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024945.1 /DEF=Homo sapiens hypothetical protein FLJ12888 (FLJ12888), mRNA. /FEA=mRNA /GEN=FLJ12888 /PROD=hypothetical protein FLJ12888 /DB_XREF=gi:13376426 /UG=Hs.284137 hypothetical protein FLJ12888 /FL=gb:NM_024945.1 NM_024945 RecQ mediated genome instability 1 RMI1 80010 NM_024945 /// XM_005252211 /// XM_005252213 0006260 // DNA replication // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 218980_at NM_025135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025135.1 /DEF=Homo sapiens hypothetical protein FLJ22297 (KIAA1695), mRNA. /FEA=mRNA /GEN=KIAA1695 /PROD=hypothetical protein KIAA1695 /DB_XREF=gi:13399325 /UG=Hs.288841 hypothetical protein FLJ22297 /FL=gb:NM_025135.1 NM_025135 formin homology 2 domain containing 3 FHOD3 80206 NM_001281739 /// NM_001281740 /// NM_025135 /// XM_005258346 /// XM_005258347 /// XM_005258348 /// XM_005258349 /// XM_005258350 /// XM_005258351 /// XM_005258352 /// XM_005258354 /// XM_005258355 /// XM_006722550 /// XM_006722551 0007015 // actin filament organization // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0051639 // actin filament network formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005865 // striated muscle thin filament // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 218981_at NM_020186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020186.1 /DEF=Homo sapiens DC11 protein (DC11), mRNA. /FEA=mRNA /GEN=DC11 /PROD=DC11 protein /DB_XREF=gi:9910179 /UG=Hs.42785 DC11 protein /FL=gb:AF201933.1 gb:NM_020186.1 NM_020186 ACN9 homolog (S. cerevisiae) ACN9 57001 NM_020186 0006111 // regulation of gluconeogenesis // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity 218982_s_at NM_015969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015969.1 /DEF=Homo sapiens hypothetical protein (HSPC011), mRNA. /FEA=mRNA /GEN=HSPC011 /PROD=hypothetical protein /DB_XREF=gi:7705424 /UG=Hs.44298 hypothetical protein /FL=gb:AF077035.1 gb:NM_015969.1 NM_015969 mitochondrial ribosomal protein S17 MRPS17 51373 NM_015969 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation 218983_at NM_016546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016546.1 /DEF=Homo sapiens complement C1r-like proteinase precursor, (LOC51279), mRNA. /FEA=mRNA /GEN=LOC51279 /PROD=complement C1r-like proteinase precursor, /DB_XREF=gi:7706082 /UG=Hs.98571 complement C1r-like proteinase precursor, /FL=gb:AF178985.1 gb:NM_016546.1 NM_016546 complement component 1, r subcomponent-like C1RL 51279 NM_016546 /// XM_005253385 /// XM_005253386 /// XM_005253387 /// XM_006719084 /// XM_006719085 0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218984_at NM_019042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019042.1 /DEF=Homo sapiens hypothetical protein (FLJ20485), mRNA. /FEA=mRNA /GEN=FLJ20485 /PROD=hypothetical protein /DB_XREF=gi:9506680 /UG=Hs.98806 hypothetical protein /FL=gb:BC005209.1 gb:NM_019042.1 NM_019042 pseudouridylate synthase 7 (putative) PUS7 54517 NM_019042 /// XM_005250462 /// XM_005250463 /// XM_006716030 /// XR_242250 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 218985_at NM_014580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014580.1 /DEF=Homo sapiens solute carrier family 2, (facilitated glucose transporter) member 8 (SLC2A8), mRNA. /FEA=mRNA /GEN=SLC2A8 /PROD=solute carrier family 2, (facilitated glucosetransporter) member 8 /DB_XREF=gi:7657680 /UG=Hs.10574 solute carrier family 2, (facilitated glucose transporter) member 8 /FL=gb:NM_014580.1 NM_014580 solute carrier family 2 (facilitated glucose transporter), member 8 SLC2A8 29988 NM_001271711 /// NM_001271712 /// NM_014580 /// NR_073416 /// XM_005251949 /// XM_006717084 /// XM_006717085 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0005536 // glucose binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 218986_s_at NM_017631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017631.1 /DEF=Homo sapiens hypothetical protein FLJ20035 (FLJ20035), mRNA. /FEA=mRNA /GEN=FLJ20035 /PROD=hypothetical protein FLJ20035 /DB_XREF=gi:8923037 /UG=Hs.109309 hypothetical protein FLJ20035 /FL=gb:NM_017631.1 NM_017631 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 DDX60 55601 NM_017631 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900245 // positive regulation of MDA-5 signaling pathway // inferred from mutant phenotype /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 218987_at NM_018179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018179.1 /DEF=Homo sapiens hypothetical protein FLJ10688 (FLJ10688), mRNA. /FEA=mRNA /GEN=FLJ10688 /PROD=hypothetical protein FLJ10688 /DB_XREF=gi:8922591 /UG=Hs.118793 hypothetical protein FLJ10688 /FL=gb:NM_018179.1 NM_018179 activating transcription factor 7 interacting protein ATF7IP 55729 NM_001286514 /// NM_001286515 /// NM_018179 /// NM_181352 /// XM_005253424 /// XM_006719108 /// XM_006719109 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045898 // regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from electronic annotation 218988_at NM_018656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018656.1 /DEF=Homo sapiens bladder cancer overexpressed protein (BLOV1), mRNA. /FEA=mRNA /GEN=BLOV1 /PROD=bladder cancer overexpressed protein /DB_XREF=gi:8922084 /UG=Hs.125830 bladder cancer overexpressed protein /FL=gb:AF148713.1 gb:NM_018656.1 NM_018656 solute carrier family 35, member E3 SLC35E3 55508 NM_018656 /// XM_005269006 /// XM_006719475 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 218989_x_at NM_022902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022902.1 /DEF=Homo sapiens hypothetical protein FLJ12496 (FLJ12496), mRNA. /FEA=mRNA /GEN=FLJ12496 /PROD=hypothetical protein FLJ12496 /DB_XREF=gi:12597642 /UG=Hs.129445 hypothetical protein FLJ12496 /FL=gb:NM_022902.1 NM_022902 solute carrier family 30 (zinc transporter), member 5 SLC30A5 64924 NM_001251969 /// NM_022902 /// NM_024055 /// XM_005248569 /// XM_006714672 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006829 // zinc ion transport // inferred from direct assay /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0010043 // response to zinc ion // inferred from direct assay /// 0010155 // regulation of proton transport // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0030667 // secretory granule membrane // traceable author statement 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 218990_s_at NM_005416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005416.1 /DEF=Homo sapiens small proline-rich protein 3 (SPRR3), mRNA. /FEA=mRNA /GEN=SPRR3 /PROD=small proline-rich protein 3 /DB_XREF=gi:4885606 /UG=Hs.139322 small proline-rich protein 3 /FL=gb:NM_005416.1 NM_005416 small proline-rich protein 3 SPRR3 6707 NM_001097589 /// NM_005416 0008544 // epidermis development // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0031424 // keratinization // inferred from electronic annotation /// 0042060 // wound healing // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 218991_at NM_022070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022070.1 /DEF=Homo sapiens hypothetical protein FLJ22087 (FLJ22087), mRNA. /FEA=mRNA /GEN=FLJ22087 /PROD=hypothetical protein FLJ22087 /DB_XREF=gi:11545780 /UG=Hs.17230 hypothetical protein FLJ22087 /FL=gb:NM_022070.1 NM_022070 HEAT repeat containing 6 HEATR6 63897 NM_022070 /// XM_005257570 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218992_at NM_018465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018465.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS030 (MDS030), mRNA. /FEA=mRNA /GEN=MDS030 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS030 /DB_XREF=gi:8923931 /UG=Hs.181385 uncharacterized hematopoietic stemprogenitor cells protein MDS030 /FL=gb:AF220050.1 gb:NM_018465.1 gb:AF225420.1 NM_018465 plasminogen receptor, C-terminal lysine transmembrane protein PLGRKT 55848 NM_018465 /// XM_005251510 /// XM_005251512 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0010756 // positive regulation of plasminogen activation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 218993_at NM_018146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018146.1 /DEF=Homo sapiens hypothetical protein FLJ10581 (FLJ10581), mRNA. /FEA=mRNA /GEN=FLJ10581 /PROD=hypothetical protein FLJ10581 /DB_XREF=gi:8922533 /UG=Hs.182729 hypothetical protein FLJ10581 /FL=gb:NM_018146.1 NM_018146 RNA methyltransferase like 1 RNMTL1 55178 NM_018146 /// XM_006721553 0001510 // RNA methylation // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 218994_s_at NM_022906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022906.1 /DEF=Homo sapiens hypothetical protein FLJ13195 similar to stromal antigen 3 (FLJ13195), mRNA. /FEA=mRNA /GEN=FLJ13195 /PROD=hypothetical protein FLJ13195 similar to stromalantigen 3 /DB_XREF=gi:12597648 /UG=Hs.213392 hypothetical protein FLJ13195 similar to stromal antigen 3 /FL=gb:NM_022906.1 NM_022906 stromal antigen 3-like 4 (pseudogene) STAG3L4 64940 NM_022906 /// NR_040585 /// NR_040586 218995_s_at NM_001955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001955.1 /DEF=Homo sapiens endothelin 1 (EDN1), mRNA. /FEA=mRNA /GEN=EDN1 /PROD=endothelin 1 /DB_XREF=gi:4503460 /UG=Hs.2271 endothelin 1 /FL=gb:NM_001955.1 NM_001955 endothelin 1 EDN1 1906 NM_001168319 /// NM_001955 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001821 // histamine secretion // inferred from electronic annotation /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from direct assay /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from direct assay /// 0010870 // positive regulation of receptor biosynthetic process // inferred from direct assay /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from direct assay /// 0014824 // artery smooth muscle contraction // traceable author statement /// 0014826 // vein smooth muscle contraction // inferred from direct assay /// 0015758 // glucose transport // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0030072 // peptide hormone secretion // inferred from direct assay /// 0030185 // nitric oxide transport // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0031583 // phospholipase D-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from direct assay /// 0042313 // protein kinase C deactivation // inferred from direct assay /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0043179 // rhythmic excitation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0045321 // leukocyte activation // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // traceable author statement /// 0045793 // positive regulation of cell size // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from direct assay /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051771 // negative regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from mutant phenotype /// 0060585 // positive regulation of prostaglandin-endoperoxide synthase activity // inferred from mutant phenotype /// 0070101 // positive regulation of chemokine-mediated signaling pathway // inferred by curator /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031707 // endothelin A receptor binding // inferred from direct assay /// 0031708 // endothelin B receptor binding // inferred from direct assay 218996_at NM_013342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013342.1 /DEF=Homo sapiens TCF3 (E2A) fusion partner (in childhood Leukemia) (TFPT), mRNA. /FEA=mRNA /GEN=TFPT /PROD=TCF3 (E2A) fusion partner (in childhoodLeukemia) /DB_XREF=gi:7019370 /UG=Hs.233765 TCF3 (E2A) fusion partner (in childhood Leukemia) /FL=gb:BC001728.1 gb:BC004281.1 gb:AF052052.1 gb:NM_013342.1 NM_013342 TCF3 (E2A) fusion partner (in childhood Leukemia) TFPT 29844 NM_013342 /// XM_005258825 /// XM_005277074 /// XM_005277252 /// XM_005278261 /// XM_006725769 /// XM_006725870 /// XM_006725958 /// XM_006726057 /// XM_006726155 /// XM_006726195 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005884 // actin filament // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 218997_at NM_022490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022490.1 /DEF=Homo sapiens hypothetical protein FLJ13390 similar to PAF53 (FLJ13390), mRNA. /FEA=mRNA /GEN=FLJ13390 /PROD=hypothetical protein FLJ13390 similar to PAF53 /DB_XREF=gi:11968046 /UG=Hs.24884 hypothetical protein FLJ13390 similar to PAF53 /FL=gb:NM_022490.1 gb:BC001337.1 NM_022490 polymerase (RNA) I polypeptide E, 53kDa POLR1E 64425 NM_001282766 /// NM_022490 /// XM_005251547 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0009303 // rRNA transcription // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0001054 // RNA polymerase I activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 218998_at NM_017832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017832.1 /DEF=Homo sapiens hypothetical protein FLJ20457 (FLJ20457), mRNA. /FEA=mRNA /GEN=FLJ20457 /PROD=hypothetical protein FLJ20457 /DB_XREF=gi:8923430 /UG=Hs.29276 hypothetical protein FLJ20457 /FL=gb:AF153417.1 gb:NM_017832.1 NM_017832 family with sequence similarity 206, member A FAM206A 54942 NM_017832 0006546 // glycine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005960 // glycine cleavage complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 218999_at NM_018295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018295.1 /DEF=Homo sapiens hypothetical protein FLJ11000 (FLJ11000), mRNA. /FEA=mRNA /GEN=FLJ11000 /PROD=hypothetical protein FLJ11000 /DB_XREF=gi:8922813 /UG=Hs.302981 hypothetical protein FLJ11000 /FL=gb:NM_018295.1 NM_018295 transmembrane protein 140 TMEM140 55281 NM_018295 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219000_s_at NM_024094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024094.1 /DEF=Homo sapiens hypothetical protein MGC5528 (MGC5528), mRNA. /FEA=mRNA /GEN=MGC5528 /PROD=hypothetical protein MGC5528 /DB_XREF=gi:13129095 /UG=Hs.315167 hypothetical protein MGC5528 /FL=gb:BC001316.1 gb:NM_024094.1 NM_024094 DNA replication and sister chromatid cohesion 1 DSCC1 79075 NM_024094 /// XM_005251065 0006260 // DNA replication // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034421 // post-translational protein acetylation // inferred from mutant phenotype 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219001_s_at NM_024345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024345.1 /DEF=Homo sapiens hypothetical protein MGC10765 (MGC10765), mRNA. /FEA=mRNA /GEN=MGC10765 /PROD=hypothetical protein MGC10765 /DB_XREF=gi:13236596 /UG=Hs.317589 hypothetical protein MGC10765 /FL=gb:BC003520.1 gb:NM_024345.1 NM_024345 DDB1 and CUL4 associated factor 10 DCAF10 79269 NM_001286810 /// NM_024345 /// XM_005251577 /// XM_005251578 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219002_at NM_024622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024622.1 /DEF=Homo sapiens hypothetical protein FLJ21901 (FLJ21901), mRNA. /FEA=mRNA /GEN=FLJ21901 /PROD=hypothetical protein FLJ21901 /DB_XREF=gi:13375843 /UG=Hs.32646 hypothetical protein FLJ21901 /FL=gb:NM_024622.1 NM_024622 FAST kinase domains 1 FASTKD1 79675 NM_001281476 /// NM_024622 /// NR_104020 /// XM_006712750 /// XM_006712751 0006468 // protein phosphorylation // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219003_s_at NM_024641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024641.1 /DEF=Homo sapiens hypothetical protein FLJ12838 (FLJ12838), mRNA. /FEA=mRNA /GEN=FLJ12838 /PROD=hypothetical protein FLJ12838 /DB_XREF=gi:13375878 /UG=Hs.46903 hypothetical protein FLJ12838 /FL=gb:NM_024641.1 NM_024641 mannosidase, endo-alpha MANEA 79694 NM_024641 /// XM_005267147 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0004569 // glycoprotein endo-alpha-1,2-mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219004_s_at NM_018944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018944.1 /DEF=Homo sapiens chromosome 21 open reading frame 45 (C21ORF45), mRNA. /FEA=mRNA /GEN=C21ORF45 /PROD=chromosome 21 open reading frame 45 /DB_XREF=gi:9506436 /UG=Hs.49932 chromosome 21 open reading frame 45 /FL=gb:NM_018944.1 NM_018944 MIS18 kinetochore protein A MIS18A 54069 NM_018944 0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0044030 // regulation of DNA methylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219005_at NM_012109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012109.1 /DEF=Homo sapiens brain-specific membrane-anchored protein (BSMAP), mRNA. /FEA=mRNA /GEN=BSMAP /PROD=brain-specific membrane-anchored proteinprecursor /DB_XREF=gi:6912273 /UG=Hs.5012 brain-specific membrane-anchored protein /FL=gb:AF186264.1 gb:NM_012109.1 NM_012109 transmembrane protein 59-like TMEM59L 25789 NM_012109 /// XM_006722719 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 219006_at NM_014165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014165.1 /DEF=Homo sapiens HSPC125 protein (HSPC125), mRNA. /FEA=mRNA /GEN=HSPC125 /PROD=HSPC125 protein /DB_XREF=gi:7661785 /UG=Hs.5232 HSPC125 protein /FL=gb:AF060508.1 gb:AF161474.1 gb:NM_014165.1 NM_014165 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 NDUFAF4 29078 NM_014165 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 219007_at NM_024647 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024647.1 /DEF=Homo sapiens hypothetical protein FLJ13287 (FLJ13287), mRNA. /FEA=mRNA /GEN=FLJ13287 /PROD=hypothetical protein FLJ13287 /DB_XREF=gi:13375888 /UG=Hs.53263 hypothetical protein FLJ13287 /FL=gb:NM_024647.1 NM_024647 nucleoporin 43kDa NUP43 348995 NM_024647 /// NM_198887 /// NR_104456 /// XM_005266960 /// XM_005266961 /// XM_005266962 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 219008_at NM_021925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021925.1 /DEF=Homo sapiens hypothetical protein FLJ21820 (FLJ21820), mRNA. /FEA=mRNA /GEN=FLJ21820 /PROD=hypothetical protein FLJ21820 /DB_XREF=gi:11345457 /UG=Hs.63300 hypothetical protein FLJ21820 /FL=gb:NM_021925.1 NM_021925 chromosome 2 open reading frame 43 C2orf43 60526 NM_001282719 /// NM_001282720 /// NM_001282721 /// NM_001282722 /// NM_001282723 /// NM_001282724 /// NM_021925 /// NR_104233 /// XR_426990 /// XR_426991 /// XR_426992 219009_at NM_021944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021944.1 /DEF=Homo sapiens hypothetical protein FLJ12154 (FLJ12154), mRNA. /FEA=mRNA /GEN=FLJ12154 /PROD=hypothetical protein FLJ12154 /DB_XREF=gi:11345485 /UG=Hs.6839 hypothetical protein FLJ12154 /FL=gb:NM_021944.1 NM_021944 chromosome 14 open reading frame 93 C14orf93 60686 NM_001130706 /// NM_001130708 /// NM_001282968 /// NM_001282969 /// NM_001282970 /// NM_021944 /// XM_005267971 /// XM_005267972 /// XM_005267973 /// XM_006720229 /// XM_006720230 /// XM_006720231 /// XM_006720232 0005576 // extracellular region // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 219010_at NM_018265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018265.1 /DEF=Homo sapiens hypothetical protein FLJ10901 (FLJ10901), mRNA. /FEA=mRNA /GEN=FLJ10901 /PROD=hypothetical protein FLJ10901 /DB_XREF=gi:8922753 /UG=Hs.73239 hypothetical protein FLJ10901 /FL=gb:NM_018265.1 NM_018265 chromosome 1 open reading frame 106 C1orf106 55765 NM_001142569 /// NM_018265 /// XM_006711445 219011_at NM_020904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020904.1 /DEF=Homo sapiens pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 4 (PLEKHA4), mRNA. /FEA=mRNA /GEN=PLEKHA4 /PROD=pleckstrin homology domain-containing, family A(phosphoinositide binding specific) member 4 /DB_XREF=gi:10190743 /UG=Hs.9469 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 4 /FL=gb:NM_020904.1 gb:AY007233.1 NM_020904 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 PLEKHA4 57664 NM_001161354 /// NM_020904 /// XM_005259107 /// XM_005259108 /// XM_005259109 /// XM_006723301 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 219012_s_at NM_020193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020193.1 /DEF=Homo sapiens GL002 protein (GL002), mRNA. /FEA=mRNA /GEN=GL002 /PROD=GL002 protein /DB_XREF=gi:9910245 /UG=Hs.9567 GL002 protein /FL=gb:AF226047.1 gb:NM_020193.1 NM_020193 chromosome 11 open reading frame 30 C11orf30 56946 NM_020193 /// XM_005274106 /// XM_005274108 /// XM_005274109 /// XM_005274112 /// XM_006718637 /// XM_006718638 /// XM_006718639 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 219013_at NM_022087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022087.1 /DEF=Homo sapiens hypothetical protein FLJ21634 (FLJ21634), mRNA. /FEA=mRNA /GEN=FLJ21634 /PROD=hypothetical protein FLJ21634 /DB_XREF=gi:11545800 /UG=Hs.97056 hypothetical protein FLJ21634 /FL=gb:NM_022087.1 NM_022087 polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 63917 NM_022087 /// XM_006716082 /// XM_006716083 /// XM_006716084 0006486 // protein glycosylation // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // inferred from sequence or structural similarity /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008593 // regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0016266 // O-glycan processing // traceable author statement /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred from sequence or structural similarity 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005112 // Notch binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219014_at NM_016619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016619.1 /DEF=Homo sapiens hypothetical protein (LOC51316), mRNA. /FEA=mRNA /GEN=LOC51316 /PROD=hypothetical protein /DB_XREF=gi:7706157 /UG=Hs.107139 hypothetical protein /FL=gb:AF208846.1 gb:NM_016619.1 NM_016619 placenta-specific 8 PLAC8 51316 NM_001130715 /// NM_001130716 /// NM_016619 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation 219015_s_at NM_018466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018466.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS031 (MDS031), mRNA. /FEA=mRNA /GEN=MDS031 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS031 /DB_XREF=gi:8923933 /UG=Hs.110853 uncharacterized hematopoietic stemprogenitor cells protein MDS031 /FL=gb:BC005336.1 gb:AF220051.1 gb:NM_018466.1 NM_018466 ALG13, UDP-N-acetylglucosaminyltransferase subunit ALG13 79868 NM_001039210 /// NM_001099922 /// NM_001168385 /// NM_001257230 /// NM_001257231 /// NM_001257234 /// NM_001257235 /// NM_001257237 /// NM_001257239 /// NM_001257240 /// NM_001257241 /// NM_018466 /// NR_033125 /// XM_005262191 /// XM_006724693 /// XM_006724694 /// XM_006724695 /// XM_006724696 /// XM_006724697 /// XM_006724698 /// XM_006724699 /// XM_006724700 /// XM_006724701 /// XM_006724702 /// XM_006724703 /// XM_006724704 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004577 // N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219016_at NM_021826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021826.1 /DEF=Homo sapiens hypothetical protein FLJ13149 (FLJ13149), mRNA. /FEA=mRNA /GEN=FLJ13149 /PROD=hypothetical protein FLJ13149 /DB_XREF=gi:11141902 /UG=Hs.112188 hypothetical protein FLJ13149 /FL=gb:NM_021826.1 NM_021826 FAST kinase domains 5 FASTKD5 60493 NM_021826 0006468 // protein phosphorylation // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219017_at NM_018638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018638.2 /DEF=Homo sapiens ethanolamine kinase (EKI1), mRNA. /FEA=mRNA /GEN=EKI1 /PROD=ethanolamine kinase /DB_XREF=gi:10092614 /UG=Hs.120439 ethanolamine kinase /FL=gb:NM_018638.2 gb:AF207600.2 NM_018638 ethanolamine kinase 1 ETNK1 55500 NM_001039481 /// NM_018638 /// XM_005253420 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219018_s_at NM_022747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022747.1 /DEF=Homo sapiens hypothetical protein FLJ22558 (FLJ22558), mRNA. /FEA=mRNA /GEN=FLJ22558 /PROD=hypothetical protein FLJ22558 /DB_XREF=gi:12232406 /UG=Hs.12186 hypothetical protein FLJ22558 /FL=gb:NM_022747.1 NM_022747 coiled-coil domain containing 85C CCDC85C 317762 NM_001144995 0007275 // multicellular organismal development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from sequence or structural similarity 219019_at NM_018494 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018494.1 /DEF=Homo sapiens leucine rich repeat and death domain containing protein (LRDD), mRNA. /FEA=mRNA /GEN=LRDD /PROD=leucine rich repeat and death domain containingprotein /DB_XREF=gi:8923912 /UG=Hs.123136 leucine rich repeat and death domain containing protein /FL=gb:AF229178.1 gb:NM_018494.1 NM_018494 p53-induced death domain protein 1 PIDD1 55367 NM_018494 /// NM_145886 /// NM_145887 /// XM_005253005 /// XM_005253006 /// XM_005253007 /// XM_005253008 /// XM_006718258 /// XR_242813 /// XR_242814 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from direct assay 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219020_at NM_022460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022460.1 /DEF=Homo sapiens hypothetical protein FLJ14249 similar to HS1 binding protein 3 (FLJ14249), mRNA. /FEA=mRNA /GEN=FLJ14249 /PROD=hypothetical protein FLJ14249 similar to HS1binding protein 3 /DB_XREF=gi:11968000 /UG=Hs.125520 hypothetical protein FLJ14249 similar to HS1 binding protein 3 /FL=gb:NM_022460.1 NM_022460 HCLS1 binding protein 3 HS1BP3 64342 NM_022460 0007154 // cell communication // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 219021_at NM_018320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018320.1 /DEF=Homo sapiens hypothetical protein FLJ11099 (FLJ11099), mRNA. /FEA=mRNA /GEN=FLJ11099 /PROD=hypothetical protein FLJ11099 /DB_XREF=gi:8922862 /UG=Hs.131731 hypothetical protein FLJ11099 /FL=gb:NM_018320.1 NM_018320 ring finger protein 121 RNF121 55298 NM_018320 /// NM_194452 /// NM_194453 /// NR_024147 /// NR_024148 /// XM_006718629 /// XM_006718630 /// XM_006718631 /// XM_006718632 /// XM_006718633 /// XM_006718634 /// XM_006718635 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219022_at NM_022895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022895.1 /DEF=Homo sapiens hypothetical protein FLJ12448 (FLJ12448), mRNA. /FEA=mRNA /GEN=FLJ12448 /PROD=hypothetical protein FLJ12448 /DB_XREF=gi:12597630 /UG=Hs.143504 hypothetical protein FLJ12448 /FL=gb:NM_022895.1 NM_022895 chromosome 12 open reading frame 43 C12orf43 64897 NM_001286191 /// NM_001286192 /// NM_001286195 /// NM_001286196 /// NM_001286197 /// NM_001286198 /// NM_022895 /// NR_104409 219023_at NM_018569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018569.1 /DEF=Homo sapiens hypothetical protein PRO0971 (PRO0971), mRNA. /FEA=mRNA /GEN=PRO0971 /PROD=hypothetical protein PRO0971 /DB_XREF=gi:8923996 /UG=Hs.152316 hypothetical protein PRO0971 /FL=gb:AL136628.1 gb:AF116612.1 gb:NM_018569.1 NM_018569 adaptor-related protein complex 1 associated regulatory protein AP1AR 55435 NM_001128426 /// NM_018569 /// XM_005263116 0001920 // negative regulation of receptor recycling // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0034315 // regulation of Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0048203 // vesicle targeting, trans-Golgi to endosome // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 2000146 // negative regulation of cell motility // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay 0019894 // kinesin binding // inferred from direct assay /// 0035650 // AP-1 adaptor complex binding // inferred from direct assay 219024_at NM_021622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021622.1 /DEF=Homo sapiens pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 1 (PLEKHA1), mRNA. /FEA=mRNA /GEN=PLEKHA1 /PROD=pleckstrin homology domain-containing, family A(phosphoinositide binding specific) member 1 /DB_XREF=gi:11055985 /UG=Hs.17757 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 1 /FL=gb:AF286160.1 gb:NM_021622.1 gb:BC001136.1 NM_021622 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 PLEKHA1 59338 NM_001001974 /// NM_001195608 /// NM_021622 /// XM_005270016 /// XM_005270017 /// XM_005270018 /// XM_005270019 /// XM_005270020 /// XM_005270021 /// XM_006717935 0001553 // luteinization // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 219025_at NM_020404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020404.1 /DEF=Homo sapiens tumor endothelial marker 1 precursor (TEM1), mRNA. /FEA=mRNA /GEN=TEM1 /PROD=tumor endothelial marker 1 precursor /DB_XREF=gi:9966884 /UG=Hs.195727 tumor endothelial marker 1 precursor /FL=gb:AF279142.1 gb:NM_020404.1 NM_020404 CD248 molecule, endosialin CD248 57124 NM_020404 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 219026_s_at NM_004841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004841.1 /DEF=Homo sapiens ras GTPase activating protein-like (NGAP), mRNA. /FEA=mRNA /GEN=NGAP /PROD=ras GTPase activating protein-like /DB_XREF=gi:4758807 /UG=Hs.227806 ras GTPase activating protein-like /FL=gb:AF047711.1 gb:NM_004841.1 NM_004841 RAS protein activator like 2 RASAL2 9462 NM_004841 /// NM_170692 /// XM_005245620 /// XM_005245621 /// XM_005245622 /// XM_006711634 0007165 // signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 219027_s_at NM_006901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006901.1 /DEF=Homo sapiens myosin IXA (MYO9A), mRNA. /FEA=mRNA /GEN=MYO9A /PROD=myosin IXA /DB_XREF=gi:5902011 /UG=Hs.23395 myosin IXA /FL=gb:AF117888.1 gb:NM_006901.1 NM_006901 myosin IXA MYO9A 4649 NM_006901 /// XM_005254404 /// XM_006720539 /// XM_006720540 /// XM_006720541 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219028_at NM_022740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022740.1 /DEF=Homo sapiens homeodomain-interacting protein kinase 2 (HIPK2), mRNA. /FEA=mRNA /GEN=HIPK2 /PROD=homeodomain-interacting protein kinase 2 /DB_XREF=gi:13430859 /UG=Hs.236131 homeodomain-interacting protein kinase 2 /FL=gb:AF208291.1 gb:NM_022740.1 NM_022740 homeodomain interacting protein kinase 2 HIPK2 28996 NM_001113239 /// NM_022740 /// XM_006715934 /// XM_006715935 /// XM_006715936 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001654 // eye development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // non-traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0030578 // PML body organization // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // traceable author statement /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060235 // lens induction in camera-type eye // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0061072 // iris morphogenesis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0016604 // nuclear body // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from physical interaction /// 0046790 // virion binding // inferred from physical interaction 219029_at NM_022483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022483.1 /DEF=Homo sapiens hypothetical protein FLJ21657 (FLJ21657), mRNA. /FEA=mRNA /GEN=FLJ21657 /PROD=hypothetical protein FLJ21657 /DB_XREF=gi:11968034 /UG=Hs.26498 hypothetical protein FLJ21657 /FL=gb:NM_022483.1 NM_022483 chromosome 5 open reading frame 28 C5orf28 64417 NM_022483 /// XM_005248333 /// XM_005248334 /// XM_005248335 /// XM_005248336 /// XM_006714485 /// XM_006714486 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219030_at NM_016058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016058.1 /DEF=Homo sapiens CGI-121 protein (LOC51002), mRNA. /FEA=mRNA /GEN=LOC51002 /PROD=CGI-121 protein /DB_XREF=gi:7705589 /UG=Hs.26706 CGI-121 protein /FL=gb:AF060921.1 gb:AF151879.1 gb:NM_016058.1 NM_016058 TP53RK binding protein TPRKB 51002 NM_016058 /// XM_005264343 /// XM_005264345 /// XM_006712026 /// XM_006712027 0008033 // tRNA processing // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 219031_s_at NM_016101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016101.1 /DEF=Homo sapiens hypothetical protein (HSPC031), mRNA. /FEA=mRNA /GEN=HSPC031 /PROD=hypothetical protein /DB_XREF=gi:7705436 /UG=Hs.268049 hypothetical protein /FL=gb:AF132971.1 gb:AF085360.1 gb:NM_016101.1 NM_016101 NIP7, nucleolar pre-rRNA processing protein NIP7 51388 NM_001199434 /// NM_016101 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219032_x_at NM_014322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014322.1 /DEF=Homo sapiens opsin 3 (encephalopsin) (OPN3), mRNA. /FEA=mRNA /GEN=OPN3 /PROD=opsin 3 (encephalopsin) /DB_XREF=gi:7657070 /UG=Hs.279926 opsin 3 (encephalopsin) /FL=gb:AF140242.1 gb:NM_014322.1 NM_014322 opsin 3 OPN3 23596 NM_001030011 /// NM_001030012 /// NM_014322 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007602 // phototransduction // non-traceable author statement /// 0009583 // detection of light stimulus // non-traceable author statement /// 0009584 // detection of visible light // non-traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008020 // G-protein coupled photoreceptor activity // non-traceable author statement /// 0009881 // photoreceptor activity // non-traceable author statement 219033_at NM_024615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024615.1 /DEF=Homo sapiens hypothetical protein FLJ21308 (FLJ21308), mRNA. /FEA=mRNA /GEN=FLJ21308 /PROD=hypothetical protein FLJ21308 /DB_XREF=gi:13375831 /UG=Hs.29977 hypothetical protein FLJ21308 /FL=gb:NM_024615.1 NM_024615 poly (ADP-ribose) polymerase family, member 8 PARP8 79668 NM_001178055 /// NM_001178056 /// NM_024615 /// XM_005248596 /// XM_005248597 /// XR_241789 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 219034_at NM_017851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017851.1 /DEF=Homo sapiens hypothetical protein FLJ20509 (FLJ20509), mRNA. /FEA=mRNA /GEN=FLJ20509 /PROD=hypothetical protein FLJ20509 /DB_XREF=gi:8923470 /UG=Hs.30634 hypothetical protein FLJ20509 /FL=gb:NM_017851.1 NM_017851 poly (ADP-ribose) polymerase family, member 16 PARP16 54956 NM_017851 /// XM_005254516 /// XM_005254518 /// XM_006720589 /// XM_006720590 /// XM_006720591 /// XM_006720592 /// XR_429459 /// XR_429460 0006471 // protein ADP-ribosylation // inferred from mutant phenotype /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070213 // protein auto-ADP-ribosylation // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0071782 // endoplasmic reticulum tubular network // inferred from mutant phenotype 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from mutant phenotype /// 0003956 // NAD(P)+-protein-arginine ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from mutant phenotype 219035_s_at NM_025126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025126.1 /DEF=Homo sapiens hypothetical protein FLJ21786 (FLJ21786), mRNA. /FEA=mRNA /GEN=FLJ21786 /PROD=hypothetical protein FLJ21786 /DB_XREF=gi:13376704 /UG=Hs.316809 hypothetical protein FLJ21786 /FL=gb:NM_025126.1 NM_025126 ring finger protein 34, E3 ubiquitin protein ligase RNF34 80196 NM_001256858 /// NM_025126 /// NM_194271 0006915 // apoptotic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001271 // negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 1901981 // phosphatidylinositol phosphate binding // inferred from direct assay 219036_at NM_024491 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024491.1 /DEF=Homo sapiens p10-binding protein (BITE), mRNA. /FEA=mRNA /GEN=BITE /PROD=p10-binding protein /DB_XREF=gi:13346499 /UG=Hs.42315 p10-binding protein /FL=gb:AF202146.1 gb:NM_024491.1 NM_024491 centrosomal protein 70kDa CEP70 80321 NM_001288964 /// NM_001288965 /// NM_001288966 /// NM_001288967 /// NM_024491 /// XM_005247802 /// XM_005247803 /// XM_005247804 /// XM_005247805 /// XM_005247806 /// XM_005247809 /// XM_005247810 /// XM_005247812 /// XM_006713767 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219037_at NM_016052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016052.1 /DEF=Homo sapiens CGI-115 protein (LOC51018), mRNA. /FEA=mRNA /GEN=LOC51018 /PROD=CGI-115 protein /DB_XREF=gi:7705619 /UG=Hs.56043 CGI-115 protein /FL=gb:AF151873.1 gb:NM_016052.1 NM_016052 ribosomal RNA processing 15 homolog (S. cerevisiae) RRP15 51018 NM_016052 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 219038_at NM_024657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024657.1 /DEF=Homo sapiens hypothetical protein FLJ11565 (FLJ11565), mRNA. /FEA=mRNA /GEN=FLJ11565 /PROD=hypothetical protein FLJ11565 /DB_XREF=gi:13375906 /UG=Hs.61763 hypothetical protein FLJ11565 /FL=gb:NM_024657.1 NM_024657 MORC family CW-type zinc finger 4 MORC4 79710 NM_001085354 /// NM_024657 /// XM_005262190 /// XM_006724691 /// XM_006724692 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219039_at NM_017789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017789.1 /DEF=Homo sapiens hypothetical protein FLJ20369 (FLJ20369), mRNA. /FEA=mRNA /GEN=FLJ20369 /PROD=hypothetical protein FLJ20369 /DB_XREF=gi:8923345 /UG=Hs.7188 hypothetical protein FLJ20369 /FL=gb:NM_017789.1 NM_017789 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C SEMA4C 54910 NM_017789 /// XM_006712606 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021535 // cell migration in hindbrain // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0042692 // muscle cell differentiation // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219040_at NM_024535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024535.1 /DEF=Homo sapiens hypothetical protein FLJ22021 (FLJ22021), mRNA. /FEA=mRNA /GEN=FLJ22021 /PROD=hypothetical protein FLJ22021 /DB_XREF=gi:13375689 /UG=Hs.7258 hypothetical protein FLJ22021 /FL=gb:NM_024535.1 NM_024535 coronin 7 CORO7 79585 NM_001201472 /// NM_001201473 /// NM_024535 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // not recorded /// 0030041 // actin filament polymerization // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // not recorded /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // not recorded 219041_s_at NM_014374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014374.1 /DEF=Homo sapiens zinc finger protein (AP4), mRNA. /FEA=mRNA /GEN=AP4 /PROD=zinc finger protein /DB_XREF=gi:7656889 /UG=Hs.90693 zinc finger protein /FL=gb:BC000363.1 gb:NM_014374.1 NM_014374 replication initiator 1 REPIN1 29803 NM_001099695 /// NM_001099696 /// NM_013400 /// NM_014374 /// XM_005249985 /// XM_006715947 /// XM_006715948 /// XM_006715949 /// XM_006715950 /// XM_006715951 /// XM_006715952 /// XM_006715953 0006260 // DNA replication // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0046839 // phospholipid dephosphorylation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 2000191 // regulation of fatty acid transport // inferred from electronic annotation /// 2001273 // regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005664 // nuclear origin of replication recognition complex // traceable author statement /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0022626 // cytosolic ribosome // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042577 // lipid phosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219042_at NM_021020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021020.1 /DEF=Homo sapiens F37Esophageal cancer-related gene-coding leucine-zipper motif (FEZ1), mRNA. /FEA=mRNA /GEN=FEZ1 /PROD=F37Esophageal cancer-related gene-codingleucine-zipper motif /DB_XREF=gi:10440565 /UG=Hs.93605 leucine zipper, putative tumor suppressor 1 /FL=gb:NM_021020.1 gb:AF123659.1 NM_021020 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219043_s_at NM_024065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024065.1 /DEF=Homo sapiens hypothetical protein MGC3062 (MGC3062), mRNA. /FEA=mRNA /GEN=MGC3062 /PROD=hypothetical protein MGC3062 /DB_XREF=gi:13129043 /UG=Hs.94576 hypothetical protein MGC3062 /FL=gb:AF267853.1 gb:BC001021.1 gb:NM_024065.1 NM_024065 phosducin-like 3 /// phosducin-like 3 pseudogene 4 PDCL3 /// PDCL3P4 79031 /// 285359 NM_024065 /// NR_002941 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0006457 // protein folding // inferred from physical interaction /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044183 // protein binding involved in protein folding // inferred from physical interaction 219044_at NM_018271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018271.1 /DEF=Homo sapiens hypothetical protein FLJ10916 (FLJ10916), mRNA. /FEA=mRNA /GEN=FLJ10916 /PROD=hypothetical protein FLJ10916 /DB_XREF=gi:8922765 /UG=Hs.9547 hypothetical protein FLJ10916 /FL=gb:NM_018271.1 NM_018271 threonine synthase-like 2 (S. cerevisiae) THNSL2 55258 NM_001244676 /// NM_001244678 /// NM_018271 /// XM_005264400 /// XM_005264401 /// XM_005264402 /// XM_005264403 /// XM_005264404 /// XM_005264405 /// XM_006712041 /// XM_006712042 /// XM_006712043 /// XM_006712044 0009071 // serine family amino acid catabolic process // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0046360 // 2-oxobutyrate biosynthetic process // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from sequence or structural similarity /// 0070905 // serine binding // inferred from sequence or structural similarity 219045_at NM_019034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019034.1 /DEF=Homo sapiens hypothetical protein (RIF), mRNA. /FEA=mRNA /GEN=RIF /PROD=hypothetical protein /DB_XREF=gi:9506666 /UG=Hs.96593 hypothetical protein /FL=gb:AF239923.1 gb:NM_019034.1 NM_019034 ras homolog family member F (in filopodia) RHOF 54509 NM_019034 0006184 // GTP catabolic process // non-traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 219046_s_at NM_022062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022062.1 /DEF=Homo sapiens hypothetical protein FLJ13074 (FLJ13074), mRNA. /FEA=mRNA /GEN=FLJ13074 /PROD=hypothetical protein FLJ13074 /DB_XREF=gi:11545768 /UG=Hs.10043 hypothetical protein FLJ13074 /FL=gb:NM_022062.1 NM_022062 PBX/knotted 1 homeobox 2 PKNOX2 63876 NM_022062 /// XM_005271642 /// XM_005271643 /// XM_006718894 /// XM_006718895 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 219047_s_at NM_024706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024706.1 /DEF=Homo sapiens hypothetical protein FLJ13479 (FLJ13479), mRNA. /FEA=mRNA /GEN=FLJ13479 /PROD=hypothetical protein FLJ13479 /DB_XREF=gi:13375998 /UG=Hs.102928 hypothetical protein FLJ13479 /FL=gb:NM_024706.1 NM_024706 zinc finger protein 668 ZNF668 79759 NM_001172668 /// NM_001172669 /// NM_001172670 /// NM_024706 /// XM_005255579 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219048_at NM_012327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012327.1 /DEF=Homo sapiens phosphatidylinositol glycan, class N (PIGN), mRNA. /FEA=mRNA /GEN=PIGN /PROD=phosphatidylinositol glycan, class N /DB_XREF=gi:6912499 /UG=Hs.108787 phosphatidylinositol glycan, class N /FL=gb:AF109219.1 gb:NM_012327.1 NM_012327 phosphatidylinositol glycan anchor biosynthesis, class N PIGN 23556 NM_012327 /// NM_176787 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219049_at NM_018371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018371.1 /DEF=Homo sapiens hypothetical protein FLJ11264 (FLJ11264), mRNA. /FEA=mRNA /GEN=FLJ11264 /PROD=hypothetical protein FLJ11264 /DB_XREF=gi:8922959 /UG=Hs.11260 hypothetical protein FLJ11264 /FL=gb:NM_018371.1 NM_018371 chondroitin sulfate N-acetylgalactosaminyltransferase 1 CSGALNACT1 55790 NM_001130518 /// NM_018371 /// NR_024040 /// XM_006716358 /// XM_006716359 /// XM_006716360 /// XM_006716361 /// XM_006716362 /// XM_006716363 /// XM_006716364 /// XM_006716365 /// XM_006716366 0001958 // endochondral ossification // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008037 // cell recognition // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // non-traceable author statement /// 0019276 // UDP-N-acetylgalactosamine metabolic process // inferred from direct assay /// 0030166 // proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030210 // heparin biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046398 // UDP-glucuronate metabolic process // inferred from direct assay /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0050653 // chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred by curator /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008376 // acetylgalactosaminyltransferase activity // inferred from direct assay /// 0008376 // acetylgalactosaminyltransferase activity // inferred from sequence or structural similarity /// 0008955 // peptidoglycan glycosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement /// 0047237 // glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay 219050_s_at NM_014205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014205.1 /DEF=Homo sapiens chromosome 11 open reading frame 5 (C11ORF5), mRNA. /FEA=mRNA /GEN=C11ORF5 /PROD=chromosome 11 open reading frame 5 /DB_XREF=gi:7656935 /UG=Hs.121025 chromosome 11 open reading frame 5 /FL=gb:AF119497.1 gb:NM_014205.1 NM_014205 zinc finger, HIT-type containing 2 ZNHIT2 741 NM_014205 0046872 // metal ion binding // inferred from electronic annotation 219051_x_at NM_024042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024042.1 /DEF=Homo sapiens hypothetical protein MGC2601 (MGC2601), mRNA. /FEA=mRNA /GEN=MGC2601 /PROD=hypothetical protein MGC2601 /DB_XREF=gi:13128999 /UG=Hs.124915 hypothetical protein MGC2601 /FL=gb:BC000662.1 gb:NM_024042.1 NM_024042 meteorin, glial cell differentiation regulator METRN 79006 NM_024042 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 219052_at NM_024747 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024747.1 /DEF=Homo sapiens hypothetical protein FLJ22501 (FLJ22501), mRNA. /FEA=mRNA /GEN=FLJ22501 /PROD=hypothetical protein FLJ22501 /DB_XREF=gi:13376073 /UG=Hs.125133 hypothetical protein FLJ22501 /FL=gb:NM_024747.1 NM_024747 Hermansky-Pudlak syndrome 6 HPS6 79803 NM_024747 0006996 // organelle organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0072657 // protein localization to membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031084 // BLOC-2 complex // inferred from physical interaction /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 219053_s_at NM_017966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017966.1 /DEF=Homo sapiens hypothetical protein FLJ20847 (FLJ20847), mRNA. /FEA=mRNA /GEN=FLJ20847 /PROD=hypothetical protein FLJ20847 /DB_XREF=gi:8923694 /UG=Hs.13479 hypothetical protein FLJ20847 /FL=gb:NM_017966.1 NM_017966 vacuolar protein sorting 37 homolog C (S. cerevisiae) VPS37C 55048 NM_017966 /// XM_005274077 /// XM_005274078 /// XM_005274079 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 219054_at NM_024563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024563.1 /DEF=Homo sapiens hypothetical protein FLJ14054 (FLJ14054), mRNA. /FEA=mRNA /GEN=FLJ14054 /PROD=hypothetical protein FLJ14054 /DB_XREF=gi:13375730 /UG=Hs.13528 hypothetical protein FLJ14054 /FL=gb:NM_024563.1 NM_024563 natriuretic peptide receptor 3 NPR3 4883 NM_000908 /// NM_001204375 /// NM_001204376 /// NM_024563 /// XM_005248309 /// XM_005248310 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from sequence or structural similarity /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0030157 // pancreatic juice secretion // inferred from electronic annotation /// 0033688 // regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008528 // G-protein coupled peptide receptor activity // inferred from sequence or structural similarity /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from sequence or structural similarity /// 0042562 // hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 219055_at NM_018079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018079.1 /DEF=Homo sapiens hypothetical protein FLJ10379 (FLJ10379), mRNA. /FEA=mRNA /GEN=FLJ10379 /PROD=hypothetical protein FLJ10379 /DB_XREF=gi:8922391 /UG=Hs.14229 hypothetical protein FLJ10379 /FL=gb:NM_018079.1 NM_018079 S1 RNA binding domain 1 SRBD1 55133 NM_018079 /// XM_005264398 /// XR_426987 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 219056_at NM_024570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024570.1 /DEF=Homo sapiens hypothetical protein FLJ11712 (FLJ11712), mRNA. /FEA=mRNA /GEN=FLJ11712 /PROD=hypothetical protein FLJ11712 /DB_XREF=gi:13375741 /UG=Hs.14920 hypothetical protein FLJ11712 /FL=gb:NM_024570.1 NM_024570 ribonuclease H2, subunit B RNASEH2B 79621 NM_001142279 /// NM_024570 /// XM_005266524 /// XM_005266525 /// XM_006719867 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006401 // RNA catabolic process // inferred from direct assay /// 0009259 // ribonucleotide metabolic process // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 2000001 // regulation of DNA damage checkpoint // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0032299 // ribonuclease H2 complex // inferred from direct assay 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from electronic annotation 219057_at NM_024816 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024816.1 /DEF=Homo sapiens hypothetical protein FLJ23282 (FLJ23282), mRNA. /FEA=mRNA /GEN=FLJ23282 /PROD=hypothetical protein FLJ23282 /DB_XREF=gi:13376207 /UG=Hs.170253 hypothetical protein FLJ23282 /FL=gb:NM_024816.1 NM_024816 rabaptin, RAB GTPase binding effector protein 2 RABEP2 79874 NM_024816 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 219058_x_at NM_022164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022164.1 /DEF=Homo sapiens P3ECSL (LIECG3), mRNA. /FEA=mRNA /GEN=LIECG3 /PROD=P3ECSL /DB_XREF=gi:11545917 /UG=Hs.173508 P3ECSL /FL=gb:AF205436.1 gb:AB050716.1 gb:NM_022164.1 gb:AF236150.1 NM_022164 tubulointerstitial nephritis antigen-like 1 TINAGL1 64129 NM_001204414 /// NM_001204415 /// NM_022164 /// XM_005271106 /// XM_005271107 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation 219059_s_at AL574194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574194 /FEA=EST /DB_XREF=gi:12934166 /DB_XREF=est:AL574194 /CLONE=CS0DI039YJ06 (3 prime) /UG=Hs.17917 extracellular link domain-containing 1 /FL=gb:AF118108.1 gb:NM_006691.1 AL574194 lymphatic vessel endothelial hyaluronan receptor 1 LYVE1 10894 NM_006691 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation 219060_at NM_018024 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018024.1 /DEF=Homo sapiens hypothetical protein FLJ10204 (FLJ10204), mRNA. /FEA=mRNA /GEN=FLJ10204 /PROD=hypothetical protein FLJ10204 /DB_XREF=gi:8922280 /UG=Hs.18029 hypothetical protein FLJ10204 /FL=gb:NM_018024.1 NM_018024 WDYHV motif containing 1 WDYHV1 55093 NM_001283024 /// NM_001283027 /// NM_018024 /// XM_006716597 0006464 // cellular protein modification process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0070773 // protein-N-terminal glutamine amidohydrolase activity // inferred from sequence or structural similarity 219061_s_at NM_006014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006014.1 /DEF=Homo sapiens DNA segment on chromosome X (unique) 9879 expressed sequence (DXS9879E), mRNA. /FEA=mRNA /GEN=DXS9879E /PROD=ITBA2 protein /DB_XREF=gi:5174432 /UG=Hs.18212 DNA segment on chromosome X (unique) 9879 expressed sequence /FL=gb:NM_006014.1 NM_006014 L antigen family, member 3 LAGE3 8270 NM_006014 0008033 // tRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 219062_s_at NM_017742 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017742.1 /DEF=Homo sapiens hypothetical protein FLJ20281 (FLJ20281), mRNA. /FEA=mRNA /GEN=FLJ20281 /PROD=hypothetical protein FLJ20281 /DB_XREF=gi:8923259 /UG=Hs.18800 hypothetical protein FLJ20281 /FL=gb:NM_017742.1 NM_017742 zinc finger, CCHC domain containing 2 ZCCHC2 54877 NM_017742 /// XM_006722493 /// XM_006722494 /// XR_245462 /// XR_430076 0007154 // cell communication // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219063_at NM_024319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024319.1 /DEF=Homo sapiens hypothetical protein MGC4174 (MGC4174), mRNA. /FEA=mRNA /GEN=MGC4174 /PROD=hypothetical protein MGC4174 /DB_XREF=gi:13236558 /UG=Hs.19769 hypothetical protein MGC4174 /FL=gb:BC002843.1 gb:NM_024319.1 NM_024319 chromosome 1 open reading frame 35 C1orf35 79169 NM_024319 /// XR_247040 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219064_at NM_030569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030569.1 /DEF=Homo sapiens hypothetical protein MGC10848 (MGC10848), mRNA. /FEA=mRNA /GEN=MGC10848 /PROD=hypothetical protein MGC10848 /DB_XREF=gi:13386477 /UG=Hs.207443 hypothetical protein MGC10848 /FL=gb:BC004282.1 gb:NM_030569.1 NM_030569 inter-alpha-trypsin inhibitor heavy chain family, member 5 ITIH5 80760 NM_001001851 /// NM_030569 /// NM_032817 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 219065_s_at NM_015955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015955.1 /DEF=Homo sapiens CGI-27 protein (LOC51072), mRNA. /FEA=mRNA /GEN=LOC51072 /PROD=CGI-27 protein /DB_XREF=gi:7705719 /UG=Hs.20814 CGI-27 protein /FL=gb:AF132961.1 gb:NM_015955.1 NM_015955 dpy-30 homolog (C. elegans) /// mediator of cell motility 1 DPY30 /// MEMO1 51072 /// 84661 NM_001137602 /// NM_015955 /// NM_032574 /// XM_005264351 /// XM_005264352 /// XM_005264612 /// XM_006712028 /// XM_006712117 /// XM_006712118 /// XM_006712119 /// XR_244937 /// XR_426982 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 219066_at NM_021823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021823.1 /DEF=Homo sapiens hypothetical protein MDS018 (MDS018), mRNA. /FEA=mRNA /GEN=MDS018 /PROD=hypothetical protein MDS018 /DB_XREF=gi:11141896 /UG=Hs.24647 hypothetical protein MDS018 /FL=gb:AF182419.1 gb:NM_021823.1 NM_021823 phosphopantothenoylcysteine decarboxylase PPCDC 60490 NM_021823 /// XM_005254579 /// XM_006720630 /// XM_006720631 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004633 // phosphopantothenoylcysteine decarboxylase activity // inferred from direct assay /// 0004633 // phosphopantothenoylcysteine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 219067_s_at NM_017615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017615.1 /DEF=Homo sapiens hypothetical protein FLJ20003 (FLJ20003), mRNA. /FEA=mRNA /GEN=FLJ20003 /PROD=hypothetical protein FLJ20003 /DB_XREF=gi:8923008 /UG=Hs.258798 hypothetical protein FLJ20003 /FL=gb:NM_017615.1 NM_017615 non-SMC element 4 homolog A (S. cerevisiae) NSMCE4A 54780 NM_001167865 /// NM_017615 /// XM_005269928 /// XM_005269929 /// XM_005269930 /// XR_428706 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030915 // Smc5-Smc6 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219068_x_at NM_018188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018188.1 /DEF=Homo sapiens hypothetical protein FLJ10709 (FLJ10709), mRNA. /FEA=mRNA /GEN=FLJ10709 /PROD=hypothetical protein FLJ10709 /DB_XREF=gi:8922608 /UG=Hs.273357 hypothetical protein FLJ10709 /FL=gb:NM_018188.1 NM_018188 ATPase family, AAA domain containing 3A /// ATPase family, AAA domain containing 3B ATAD3A /// ATAD3B 55210 /// 83858 NM_001170535 /// NM_001170536 /// NM_018188 /// NM_031921 /// XM_005244806 /// XM_005244808 /// XR_241045 /// XR_426633 0008152 // metabolic process // inferred from electronic annotation /// 0016049 // cell growth // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 219069_at NM_017704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017704.1 /DEF=Homo sapiens hypothetical protein FLJ20189 (FLJ20189), mRNA. /FEA=mRNA /GEN=FLJ20189 /PROD=hypothetical protein FLJ20189 /DB_XREF=gi:8923180 /UG=Hs.29052 hypothetical protein FLJ20189 /FL=gb:NM_017704.1 NM_017704 ankyrin repeat domain 49 ANKRD49 54851 NM_017704 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred by curator 0005515 // protein binding // inferred from electronic annotation 219070_s_at NM_023948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023948.1 /DEF=Homo sapiens hypothetical protein AF053356_CDS3 (AF053356_CDS3), mRNA. /FEA=mRNA /GEN=AF053356_CDS3 /PROD=AF053356_CDS3 protein /DB_XREF=gi:13122607 /UG=Hs.296200 hypothetical protein AF053356_CDS3 /FL=gb:NM_023948.1 gb:BC005042.1 NM_023948 motile sperm domain containing 3 MOSPD3 64598 NM_001040097 /// NM_001040098 /// NM_001040099 /// NM_023948 /// XM_005250529 /// XM_005250530 /// XM_005250531 0007507 // heart development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219071_x_at NM_016458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016458.2 /DEF=Homo sapiens hypothetical protein (LOC51236), mRNA. /FEA=mRNA /GEN=LOC51236 /PROD=hypothetical protein MGC4355 /DB_XREF=gi:13124772 /UG=Hs.300224 hypothetical protein /FL=gb:BC003035.1 gb:NM_016458.2 NM_016458 HGH1 homolog (S. cerevisiae) HGH1 51236 NM_016458 0005488 // binding // inferred from electronic annotation 219072_at NM_004765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004765.1 /DEF=Homo sapiens B-cell CLLlymphoma 7C (BCL7C), mRNA. /FEA=mRNA /GEN=BCL7C /PROD=B-cell CLLlymphoma 7C /DB_XREF=gi:4757843 /UG=Hs.303197 B-cell CLLlymphoma 7C /FL=gb:NM_004765.1 NM_004765 B-cell CLL/lymphoma 7C BCL7C 9274 NM_001286526 /// NM_004765 0006915 // apoptotic process // inferred from electronic annotation 219073_s_at NM_017784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017784.1 /DEF=Homo sapiens hypothetical protein FLJ20363 (FLJ20363), mRNA. /FEA=mRNA /GEN=FLJ20363 /PROD=hypothetical protein FLJ20363 /DB_XREF=gi:8923336 /UG=Hs.321622 hypothetical protein FLJ20363 /FL=gb:BC003168.1 gb:NM_017784.1 NM_017784 oxysterol binding protein-like 10 OSBPL10 114884 NM_001174060 /// NM_017784 /// XM_005264843 /// XM_005264844 /// XM_005264845 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 219074_at NM_018241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018241.1 /DEF=Homo sapiens hypothetical protein FLJ10846 (FLJ10846), mRNA. /FEA=mRNA /GEN=FLJ10846 /PROD=hypothetical protein FLJ10846 /DB_XREF=gi:8922706 /UG=Hs.32271 hypothetical protein FLJ10846 /FL=gb:NM_018241.1 NM_018241 transmembrane protein 184C TMEM184C 55751 NM_018241 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219075_at NM_024029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024029.1 /DEF=Homo sapiens hypothetical protein MGC3262 (MGC3262), mRNA. /FEA=mRNA /GEN=MGC3262 /PROD=hypothetical protein MGC3262 /DB_XREF=gi:13128975 /UG=Hs.323213 hypothetical protein MGC3262 /FL=gb:BC000056.1 gb:NM_024029.1 NM_024029 Yip1 domain family, member 2 YIPF2 78992 NM_024029 /// XM_005260069 /// XM_005260070 /// XM_005260071 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 219076_s_at NM_018663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018663.1 /DEF=Homo sapiens 22kDa peroxisomal membrane protein-like (LOC55895), mRNA. /FEA=mRNA /GEN=LOC55895 /PROD=22kDa peroxisomal membrane protein-like /DB_XREF=gi:8923891 /UG=Hs.49912 22kDa peroxisomal membrane protein-like /FL=gb:AF250136.1 gb:NM_018663.1 NM_018663 peroxisomal membrane protein 2, 22kDa PXMP2 5827 NM_018663 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219077_s_at NM_016373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016373.1 /DEF=Homo sapiens WW domain-containing oxidoreductase (WWOX), mRNA. /FEA=mRNA /GEN=WWOX /PROD=FOR II /DB_XREF=gi:7706522 /UG=Hs.519 WW domain-containing oxidoreductase /FL=gb:AF211943.1 gb:NM_016373.1 gb:AF227527.1 NM_016373 WW domain containing oxidoreductase WWOX 51741 NM_001291997 /// NM_016373 /// NM_018560 /// NM_130788 /// NM_130790 /// NM_130791 /// NM_130792 /// NM_130844 /// NR_120435 /// NR_120436 /// XM_006721195 /// XR_243411 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0046983 // protein dimerization activity // traceable author statement /// 0048037 // cofactor binding // traceable author statement /// 0050662 // coenzyme binding // traceable author statement 219078_at NM_018040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018040.1 /DEF=Homo sapiens hypothetical protein FLJ10252 (FLJ10252), mRNA. /FEA=mRNA /GEN=FLJ10252 /PROD=hypothetical protein FLJ10252 /DB_XREF=gi:8922312 /UG=Hs.53913 hypothetical protein FLJ10252 /FL=gb:NM_018040.1 NM_018040 G patch domain containing 2 GPATCH2 55105 NM_018040 /// XM_005273174 /// XM_005273175 /// XM_005273176 /// XR_247030 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation 219079_at NM_016230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016230.1 /DEF=Homo sapiens flavohemoprotein b5+b5R (LOC51167), mRNA. /FEA=mRNA /GEN=LOC51167 /PROD=flavohemoprotein b5+b5R /DB_XREF=gi:7705898 /UG=Hs.5741 flavohemoprotein b5+b5R /FL=gb:AF169803.1 gb:NM_016230.1 NM_016230 cytochrome b5 reductase 4 CYB5R4 51167 NM_016230 0003032 // detection of oxygen // non-traceable author statement /// 0006091 // generation of precursor metabolites and energy // inferred from direct assay /// 0006739 // NADP metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0030073 // insulin secretion // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0046677 // response to antibiotic // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003958 // NADPH-hemoprotein reductase activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016174 // NAD(P)H oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016653 // oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 219080_s_at NM_019857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019857.1 /DEF=Homo sapiens CTP synthase II (CTPS2), mRNA. /FEA=mRNA /GEN=CTPS2 /PROD=CTP synthase II /DB_XREF=gi:9789918 /UG=Hs.58553 CTP synthase II /FL=gb:AF226667.1 gb:NM_019857.1 NM_019857 CTP synthase 2 CTPS2 56474 NM_001144002 /// NM_019857 /// NM_175859 /// XM_005274562 /// XM_006724503 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044210 // 'de novo' CTP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003883 // CTP synthase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 219081_at NM_024668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024668.1 /DEF=Homo sapiens hypothetical protein FLJ20288 (FLJ20288), mRNA. /FEA=mRNA /GEN=FLJ20288 /PROD=hypothetical protein FLJ11979 /DB_XREF=gi:13386461 /UG=Hs.84045 hypothetical protein FLJ20288 /FL=gb:BC004457.1 gb:NM_024668.1 NM_024668 ankyrin repeat and KH domain containing 1 /// ANKHD1-EIF4EBP3 readthrough ANKHD1 /// ANKHD1-EIF4EBP3 54882 /// 404734 NM_001197030 /// NM_017747 /// NM_017978 /// NM_020690 /// NM_024668 0006417 // regulation of translation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // non-traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation /// 0030371 // translation repressor activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 219082_at NM_015944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015944.1 /DEF=Homo sapiens CGI-14 protein (LOC51005), mRNA. /FEA=mRNA /GEN=LOC51005 /PROD=CGI-14 protein /DB_XREF=gi:7705595 /UG=Hs.9204 CGI-14 protein /FL=gb:AF132948.1 gb:NM_015944.1 NM_015944 amidohydrolase domain containing 2 /// cementum protein 1 AMDHD2 /// CEMP1 51005 /// 752014 NM_001048212 /// NM_001145815 /// NM_015944 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008448 // N-acetylglucosamine-6-phosphate deacetylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219083_at NM_018130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018130.1 /DEF=Homo sapiens hypothetical protein FLJ10539 (FLJ10539), mRNA. /FEA=mRNA /GEN=FLJ10539 /PROD=hypothetical protein FLJ10539 /DB_XREF=gi:8922499 /UG=Hs.93391 hypothetical protein FLJ10539 /FL=gb:NM_018130.1 NM_018130 SHQ1, H/ACA ribonucleoprotein assembly factor SHQ1 55164 NM_018130 0022618 // ribonucleoprotein complex assembly // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 2000233 // negative regulation of rRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219084_at NM_022455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022455.1 /DEF=Homo sapiens hypothetical protein FLJ22263 similar to nuclear receptor-binding SET-domain protein 1 (FLJ22263), mRNA. /FEA=mRNA /GEN=FLJ22263 /PROD=hypothetical protein FLJ22263 similar to nuclearreceptor-binding SET-domain protein 1 /DB_XREF=gi:11967992 /UG=Hs.99010 hypothetical protein FLJ22263 similar to nuclear receptor-binding SET-domain protein 1 /FL=gb:NM_022455.1 NM_022455 nuclear receptor binding SET domain protein 1 NSD1 64324 NM_022455 /// NM_172349 /// XM_005265959 /// XM_005265960 /// XM_005265961 /// XM_005265962 /// XM_006714901 /// XM_006714902 /// XM_006714903 /// XM_006714904 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010452 // histone H3-K36 methylation // inferred from direct assay /// 0010452 // histone H3-K36 methylation // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation /// 0034770 // histone H4-K20 methylation // inferred from sequence or structural similarity /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from sequence or structural similarity /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0042054 // histone methyltransferase activity // inferred from electronic annotation /// 0042799 // histone methyltransferase activity (H4-K20 specific) // inferred from sequence or structural similarity /// 0042974 // retinoic acid receptor binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity /// 0046966 // thyroid hormone receptor binding // inferred from sequence or structural similarity /// 0046975 // histone methyltransferase activity (H3-K36 specific) // inferred from direct assay /// 0046975 // histone methyltransferase activity (H3-K36 specific) // inferred from sequence or structural similarity /// 0050681 // androgen receptor binding // inferred from direct assay 219085_s_at NM_024707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024707.1 /DEF=Homo sapiens hypothetical protein FLJ13956 (FLJ13956), mRNA. /FEA=mRNA /GEN=FLJ13956 /PROD=hypothetical protein FLJ13956 /DB_XREF=gi:13376000 /UG=Hs.102991 hypothetical protein FLJ13956 /FL=gb:NM_024707.1 NM_024707 gem (nuclear organelle) associated protein 7 GEMIN7 79760 NM_001007269 /// NM_001007270 /// NM_024707 /// XM_005259262 /// XM_005259263 /// XM_005259264 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219086_at NM_018335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018335.1 /DEF=Homo sapiens hypothetical protein FLJ11132 (FLJ11132), mRNA. /FEA=mRNA /GEN=FLJ11132 /PROD=hypothetical protein FLJ11132 /DB_XREF=gi:8922889 /UG=Hs.106005 hypothetical protein FLJ11132 /FL=gb:NM_018335.1 NM_018335 zinc finger protein 839 ZNF839 55778 NM_001267827 /// NM_001267828 /// NM_018335 /// XM_005267850 /// XM_006720202 /// XM_006720203 0046872 // metal ion binding // inferred from electronic annotation 219087_at NM_017680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017680.1 /DEF=Homo sapiens asporin (LRR class 1) (ASPN), mRNA. /FEA=mRNA /GEN=ASPN /PROD=asporin (LRR class 1) /DB_XREF=gi:8923132 /UG=Hs.10760 asporin (LRR class 1) /FL=gb:NM_017680.1 NM_017680 asporin ASPN 54829 NM_001193335 /// NM_017680 0030282 // bone mineralization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0070171 // negative regulation of tooth mineralization // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation 219088_s_at AA639585 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA639585 /FEA=EST /DB_XREF=gi:2563364 /DB_XREF=est:nq82g04.s1 /CLONE=IMAGE:1158870 /UG=Hs.11110 hypothetical protein MGC2508 /FL=gb:NM_024327.1 AA639585 zinc finger protein 576 ZNF576 79177 NM_001145347 /// NM_024327 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219089_s_at NM_024327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024327.1 /DEF=Homo sapiens hypothetical protein MGC2508 (MGC2508), mRNA. /FEA=mRNA /GEN=MGC2508 /PROD=hypothetical protein MGC2508 /DB_XREF=gi:13236574 /UG=Hs.11110 hypothetical protein MGC2508 /FL=gb:NM_024327.1 NM_024327 zinc finger protein 576 ZNF576 79177 NM_001145347 /// NM_024327 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219090_at NM_020689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020689.2 /DEF=Homo sapiens sodium calcium exchanger (NCKX3), mRNA. /FEA=mRNA /GEN=NCKX3 /PROD=sodium calcium exchanger /DB_XREF=gi:10518346 /UG=Hs.12321 sodium calcium exchanger /FL=gb:AF169257.2 gb:NM_020689.2 NM_020689 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 SLC24A3 57419 NM_020689 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008273 // calcium, potassium:sodium antiporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 219091_s_at NM_024756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024756.1 /DEF=Homo sapiens hypothetical protein FLJ13465 (FLJ13465), mRNA. /FEA=mRNA /GEN=FLJ13465 /PROD=hypothetical protein FLJ13465 /DB_XREF=gi:13376090 /UG=Hs.127216 hypothetical protein FLJ13465 /FL=gb:NM_024756.1 NM_024756 multimerin 2 MMRN2 79812 NM_024756 /// XM_005270153 /// XM_006717970 0001525 // angiogenesis // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219092_s_at NM_022755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022755.1 /DEF=Homo sapiens hypothetical protein FLJ13163 (FLJ13163), mRNA. /FEA=mRNA /GEN=FLJ13163 /PROD=hypothetical protein FLJ13163 /DB_XREF=gi:12232422 /UG=Hs.16603 hypothetical protein FLJ13163 /FL=gb:NM_022755.1 NM_022755 inositol 1,3,4,5,6-pentakisphosphate 2-kinase IPPK 64768 NM_022755 /// XM_006717235 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0052746 // inositol phosphorylation // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035299 // inositol pentakisphosphate 2-kinase activity // inferred from direct assay 219093_at NM_017933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017933.1 /DEF=Homo sapiens hypothetical protein FLJ20701 (FLJ20701), mRNA. /FEA=mRNA /GEN=FLJ20701 /PROD=hypothetical protein FLJ20701 /DB_XREF=gi:8923631 /UG=Hs.169764 hypothetical protein FLJ20701 /FL=gb:NM_017933.1 NM_017933 phosphotyrosine interaction domain containing 1 PID1 55022 NM_001100818 /// NM_017933 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006112 // energy reserve metabolic process // inferred by curator /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010635 // regulation of mitochondrial fusion // inferred by curator /// 0044320 // cellular response to leptin stimulus // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051881 // regulation of mitochondrial membrane potential // traceable author statement /// 0070346 // positive regulation of fat cell proliferation // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 0071354 // cellular response to interleukin-6 // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // non-traceable author statement /// 0071398 // cellular response to fatty acid // inferred from sequence or structural similarity /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090298 // negative regulation of mitochondrial DNA replication // inferred from mutant phenotype /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001170 // negative regulation of ATP biosynthetic process // inferred from mutant phenotype /// 2001171 // positive regulation of ATP biosynthetic process // inferred from sequence or structural similarity /// 2001274 // negative regulation of glucose import in response to insulin stimulus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219094_at NM_014154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014154.1 /DEF=Homo sapiens HSPC056 protein (HSPC056), mRNA. /FEA=mRNA /GEN=HSPC056 /PROD=HSPC056 protein /DB_XREF=gi:7661763 /UG=Hs.175038 HSPC056 protein /FL=gb:AF161541.1 gb:NM_014154.1 NM_014154 armadillo repeat containing 8 ARMC8 25852 NM_001267041 /// NM_001267042 /// NM_001282342 /// NM_014154 /// NM_015396 /// NM_213654 /// XM_006713564 /// XM_006713565 /// XM_006713566 /// XM_006713567 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219095_at NM_005090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005090.1 /DEF=Homo sapiens phospholipase A2, group IVB (cytosolic) (PLA2G4B), mRNA. /FEA=mRNA /GEN=PLA2G4B /PROD=phospholipase A2, group IVB (cytosolic) /DB_XREF=gi:4826913 /UG=Hs.198161 phospholipase A2, group IVB (cytosolic) /FL=gb:AF065215.1 gb:NM_005090.1 gb:AF121908.1 NM_005090 JMJD7-PLA2G4B readthrough /// phospholipase A2, group IVB (cytosolic) JMJD7-PLA2G4B /// PLA2G4B 8681 /// 100137049 NM_001114633 /// NM_001198588 /// NM_005090 /// NR_015346 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007567 // parturition // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046475 // glycerophospholipid catabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0004622 // lysophospholipase activity // non-traceable author statement /// 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from direct assay 219096_at NM_024585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024585.1 /DEF=Homo sapiens hypothetical protein FLJ22160 (FLJ22160), mRNA. /FEA=mRNA /GEN=FLJ22160 /PROD=hypothetical protein FLJ22160 /DB_XREF=gi:13375769 /UG=Hs.21568 hypothetical protein FLJ22160 /FL=gb:NM_024585.1 NM_024585 armadillo repeat containing 7 ARMC7 79637 NM_024585 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219097_x_at NM_024104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024104.1 /DEF=Homo sapiens hypothetical protein MGC2747 (MGC2747), mRNA. /FEA=mRNA /GEN=MGC2747 /PROD=hypothetical protein MGC2747 /DB_XREF=gi:13129111 /UG=Hs.227203 hypothetical protein MGC2747 /FL=gb:BC001680.1 gb:BC001948.1 gb:NM_024104.1 NM_024104 small integral membrane protein 7 SMIM7 79086 NM_024104 /// XM_005260074 /// XR_244083 /// XR_244084 /// XR_244085 /// XR_244086 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219098_at NM_014520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014520.1 /DEF=Homo sapiens MYB binding protein (P160) 1a (MYBBP1A), mRNA. /FEA=mRNA /GEN=MYBBP1A /PROD=MYB binding protein (P160) 1a /DB_XREF=gi:7657350 /UG=Hs.22824 MYB binding protein (P160) 1a /FL=gb:AF147709.1 gb:NM_014520.1 NM_014520 MYB binding protein (P160) 1a MYBBP1A 10514 NM_001105538 /// NM_014520 /// XM_005256413 /// XM_006721419 0001649 // osteoblast differentiation // inferred from direct assay /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0042564 // NLS-dependent protein nuclear import complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219099_at NM_020375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020375.1 /DEF=Homo sapiens chromosome 12 open reading frame 5 (C12ORF5), mRNA. /FEA=mRNA /GEN=C12ORF5 /PROD=chromosome 12 open reading frame 5 /DB_XREF=gi:9966848 /UG=Hs.24792 chromosome 12 open reading frame 5 /FL=gb:NM_020375.1 NM_020375 chromosome 12 open reading frame 5 C12orf5 57103 NM_020375 /// XM_006718993 0008152 // metabolic process // inferred from electronic annotation /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 1901525 // negative regulation of macromitophagy // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219100_at NM_024928 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024928.1 /DEF=Homo sapiens hypothetical protein FLJ22559 (FLJ22559), mRNA. /FEA=mRNA /GEN=FLJ22559 /PROD=hypothetical protein FLJ22559 /DB_XREF=gi:13487922 /UG=Hs.273387 hypothetical protein FLJ22559 /FL=gb:NM_024928.1 NM_024928 oligonucleotide/oligosaccharide-binding fold containing 1 OBFC1 79991 NM_024928 /// XM_006717976 /// XM_006717977 0000723 // telomere maintenance // inferred from mutant phenotype /// 0010833 // telomere maintenance via telomere lengthening // inferred from mutant phenotype /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070188 // Stn1-Ten1 complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay 219101_x_at NM_024527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024527.1 /DEF=Homo sapiens hypothetical protein FLJ11743 (FLJ11743), mRNA. /FEA=mRNA /GEN=FLJ11743 /PROD=hypothetical protein FLJ11743 /DB_XREF=gi:13375673 /UG=Hs.321046 hypothetical protein FLJ11743 /FL=gb:AK021805.1 gb:NM_024527.1 NM_024527 abhydrolase domain containing 8 ABHD8 79575 NM_024527 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219102_at NM_020650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020650.1 /DEF=Homo sapiens hypothetical protein LOC57333 (LOC57333), mRNA. /FEA=mRNA /GEN=LOC57333 /PROD=hypothetical protein LOC57333 /DB_XREF=gi:10257434 /UG=Hs.39619 hypothetical protein LOC57333 /FL=gb:NM_020650.1 gb:AF183423.1 NM_020650 reticulocalbin 3, EF-hand calcium binding domain RCN3 57333 NM_020650 /// XM_005259089 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219103_at NM_017707 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017707.1 /DEF=Homo sapiens hypothetical protein FLJ20199 (FLJ20199), mRNA. /FEA=mRNA /GEN=FLJ20199 /PROD=hypothetical protein FLJ20199 /DB_XREF=gi:8923186 /UG=Hs.44579 hypothetical protein FLJ20199 /FL=gb:NM_017707.1 NM_017707 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 ASAP3 55616 NM_001143778 /// NM_017707 /// XM_005245934 0016477 // cell migration // inferred from mutant phenotype /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0032850 // positive regulation of ARF GTPase activity // inferred from direct assay /// 0051492 // regulation of stress fiber assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219104_at NM_016422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016422.1 /DEF=Homo sapiens C3HC4-like zinc finger protein (ZFP26), mRNA. /FEA=mRNA /GEN=ZFP26 /PROD=C3HC4-like zinc finger protein /DB_XREF=gi:7706776 /UG=Hs.44685 C3HC4-like zinc finger protein /FL=gb:AF214680.1 gb:NM_016422.1 NM_016422 ring finger protein 141 RNF141 50862 NM_016422 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219105_x_at NM_014321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014321.1 /DEF=Homo sapiens origin recognition complex, subunit 6 (yeast homolog)-like (ORC6L), mRNA. /FEA=mRNA /GEN=ORC6L /PROD=origin recognition complex, subunit 6 (yeasthomolog)-like /DB_XREF=gi:7657426 /UG=Hs.49760 origin recognition complex, subunit 6 (yeast homolog)-like /FL=gb:AF139658.1 gb:NM_014321.1 NM_014321 origin recognition complex, subunit 6 ORC6 23594 NM_014321 /// NR_037620 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219106_s_at NM_006063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006063.1 /DEF=Homo sapiens sarcomeric muscle protein (SARCOSIN), mRNA. /FEA=mRNA /GEN=SARCOSIN /PROD=sarcomeric muscle protein /DB_XREF=gi:5174664 /UG=Hs.50550 sarcomeric muscle protein /FL=gb:AF333387.1 gb:AF056929.1 gb:NM_006063.1 NM_006063 kelch-like family member 41 KLHL41 10324 NM_006063 0006941 // striated muscle contraction // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030239 // myofibril assembly // inferred from sequence or structural similarity /// 0031275 // regulation of lateral pseudopodium assembly // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from sequence or structural similarity /// 0045661 // regulation of myoblast differentiation // inferred from sequence or structural similarity /// 2000291 // regulation of myoblast proliferation // inferred from sequence or structural similarity /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219107_at NM_021948 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021948.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan BEHABbrevican (BCAN), mRNA. /FEA=mRNA /GEN=BCAN /PROD=chondroitin sulfate proteoglycan BEHABbrevican /DB_XREF=gi:11345493 /UG=Hs.6194 chondroitin sulfate proteoglycan BEHABbrevican /FL=gb:AF228710.1 gb:NM_021948.1 NM_021948 brevican BCAN 63827 NM_021948 /// NM_198427 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219108_x_at NM_017895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017895.1 /DEF=Homo sapiens hypothetical protein FLJ20596 (FLJ20596), mRNA. /FEA=mRNA /GEN=FLJ20596 /PROD=hypothetical protein FLJ20596 /DB_XREF=gi:8923554 /UG=Hs.65234 hypothetical protein FLJ20596 /FL=gb:NM_017895.1 NM_017895 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 /// synovial sarcoma translocation, chromosome 18 DDX27 /// SS18 6760 /// 55661 NM_001007559 /// NM_005637 /// NM_017895 /// XM_005258334 /// XM_006722527 /// XM_006723815 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219109_at NM_024532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024532.1 /DEF=Homo sapiens hypothetical protein FLJ22724 (FLJ22724), mRNA. /FEA=mRNA /GEN=FLJ22724 /PROD=hypothetical protein FLJ22724 /DB_XREF=gi:13375683 /UG=Hs.6783 hypothetical protein FLJ22724 /FL=gb:NM_024532.1 NM_024532 sperm associated antigen 16 SPAG16 79582 NM_001025436 /// NM_024532 /// NR_047659 /// NR_047660 /// XM_006712744 /// XM_006712745 /// XM_006712746 /// XM_006712747 0007283 // spermatogenesis // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0019901 // protein kinase binding // inferred from electronic annotation 219110_at NM_018983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018983.1 /DEF=Homo sapiens GAR1 protein (GAR1), mRNA. /FEA=mRNA /GEN=GAR1 /PROD=GAR1 protein /DB_XREF=gi:9506712 /UG=Hs.69851 nucleolar protein family A, member 1 (HACA small nucleolar RNPs) /FL=gb:BC003413.1 gb:NM_018983.1 NM_018983 GAR1 ribonucleoprotein GAR1 54433 NM_018983 /// NM_032993 /// XM_005263069 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031429 // box H/ACA snoRNP complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005261 // cation channel activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 219111_s_at NM_024072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024072.1 /DEF=Homo sapiens hypothetical protein MGC2835 (MGC2835), mRNA. /FEA=mRNA /GEN=MGC2835 /PROD=hypothetical protein MGC2835 /DB_XREF=gi:13129055 /UG=Hs.70582 hypothetical protein MGC2835 /FL=gb:BC001132.1 gb:BC001848.1 gb:NM_024072.1 NM_024072 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 DDX54 79039 NM_001111322 /// NM_024072 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219112_at NM_016340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016340.1 /DEF=Homo sapiens PDZ domain-containing guanine nucleotide exchange factor I (LOC51735), mRNA. /FEA=mRNA /GEN=LOC51735 /PROD=PDZ domain-containing guanine nucleotideexchange factor I /DB_XREF=gi:7706512 /UG=Hs.174795 PDZ domain-containing guanine nucleotide exchange factor I /FL=gb:AF117947.1 gb:NM_016340.1 NM_016340 Rap guanine nucleotide exchange factor (GEF) 6 RAPGEF6 51735 NM_001164386 /// NM_001164387 /// NM_001164388 /// NM_001164389 /// NM_001164390 /// NM_016340 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from direct assay /// 0030742 // GTP-dependent protein binding // inferred from direct assay 219113_x_at NM_016246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016246.1 /DEF=Homo sapiens retinal short-chain dehydrogenasereductase retSDR3 (LOC51171), mRNA. /FEA=mRNA /GEN=LOC51171 /PROD=retinal short-chain dehydrogenasereductaseretSDR3 /DB_XREF=gi:7705906 /UG=Hs.18788 retinal short-chain dehydrogenasereductase retSDR3 /FL=gb:AF126781.1 gb:NM_016246.1 NM_016246 hydroxysteroid (17-beta) dehydrogenase 14 HSD17B14 51171 NM_016246 /// XM_005258969 /// XM_005258970 /// XR_243938 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006706 // steroid catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047045 // testosterone 17-beta-dehydrogenase (NADP+) activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 219114_at NM_016210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016210.1 /DEF=Homo sapiens g20 protein (LOC51161), mRNA. /FEA=mRNA /GEN=LOC51161 /PROD=g20 protein /DB_XREF=gi:7705886 /UG=Hs.21050 g20 protein /FL=gb:AF188706.1 gb:NM_016210.1 NM_016210 chromosome 3 open reading frame 18 C3orf18 51161 NM_001171740 /// NM_001171741 /// NM_001171743 /// NM_016210 /// XM_006713187 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219115_s_at NM_014432 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014432.1 /DEF=Homo sapiens interleukin 20 receptor, alpha (IL20RA), mRNA. /FEA=mRNA /GEN=IL20RA /PROD=interleukin 20 receptor, alpha /DB_XREF=gi:7657690 /UG=Hs.21814 interleukin 20 receptor, alpha /FL=gb:AF184971.1 gb:NM_014432.1 NM_014432 interleukin 20 receptor, alpha IL20RA 53832 NM_001278722 /// NM_001278723 /// NM_001278724 /// NM_014432 /// XM_006715505 /// XM_006715506 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042015 // interleukin-20 binding // inferred from electronic annotation 219116_s_at NM_018185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018185.1 /DEF=Homo sapiens hypothetical protein FLJ10704 (FLJ10704), mRNA. /FEA=mRNA /GEN=FLJ10704 /PROD=hypothetical protein FLJ10704 /DB_XREF=gi:8922602 /UG=Hs.23618 hypothetical protein FLJ10704 /FL=gb:NM_018185.1 NM_018185 DCN1, defective in cullin neddylation 1, domain containing 2 DCUN1D2 55208 NM_001014283 /// NM_018185 /// XM_005268320 /// XM_005268321 /// XM_006719974 /// XM_006719975 /// XR_245842 0005515 // protein binding // inferred from electronic annotation 219117_s_at NM_016594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016594.1 /DEF=Homo sapiens FK506 binding protein precursor (LOC51303), mRNA. /FEA=mRNA /GEN=LOC51303 /PROD=FK506 binding protein precursor /DB_XREF=gi:7706130 /UG=Hs.24048 FK506 binding protein precursor /FL=gb:AF238079.1 gb:NM_016594.1 NM_016594 FK506 binding protein 11, 19 kDa FKBP11 51303 NM_001143781 /// NM_001143782 /// NM_016594 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation 219118_at NM_016594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016594.1 /DEF=Homo sapiens FK506 binding protein precursor (LOC51303), mRNA. /FEA=mRNA /GEN=LOC51303 /PROD=FK506 binding protein precursor /DB_XREF=gi:7706130 /UG=Hs.24048 FK506 binding protein precursor /FL=gb:AF238079.1 gb:NM_016594.1 NM_016594 FK506 binding protein 11, 19 kDa FKBP11 51303 NM_001143781 /// NM_001143782 /// NM_016594 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation 219119_at NM_016200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016200.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein LSm8 (LOC51691), mRNA. /FEA=mRNA /GEN=LOC51691 /PROD=U6 snRNA-associated Sm-like protein LSm8 /DB_XREF=gi:7706424 /UG=Hs.241578 U6 snRNA-associated Sm-like protein LSm8 /FL=gb:BC002742.1 gb:AF182294.1 gb:NM_016200.1 NM_016200 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) LSM8 51691 NM_016200 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 219120_at NM_025203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025203.1 /DEF=Homo sapiens hypothetical protein FLJ21945 (FLJ21945), mRNA. /FEA=mRNA /GEN=FLJ21945 /PROD=hypothetical protein FLJ21945 /DB_XREF=gi:13376797 /UG=Hs.24624 hypothetical protein FLJ21945 /FL=gb:NM_025203.1 NM_025203 chromosome 2 open reading frame 44 C2orf44 80304 NM_001142319 /// NM_025203 219121_s_at NM_017697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017697.1 /DEF=Homo sapiens hypothetical protein FLJ20171 (FLJ20171), mRNA. /FEA=mRNA /GEN=FLJ20171 /PROD=hypothetical protein FLJ20171 /DB_XREF=gi:8923166 /UG=Hs.24743 hypothetical protein FLJ20171 /FL=gb:NM_017697.1 NM_017697 epithelial splicing regulatory protein 1 ESRP1 54845 NM_001034915 /// NM_001122825 /// NM_001122826 /// NM_001122827 /// NM_017697 /// XM_005250991 /// XM_005250992 /// XR_242393 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay 219122_s_at NM_017872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017872.1 /DEF=Homo sapiens hypothetical protein FLJ20546 (FLJ20546), mRNA. /FEA=mRNA /GEN=FLJ20546 /PROD=hypothetical protein FLJ20546 /DB_XREF=gi:8923513 /UG=Hs.279896 hypothetical protein FLJ20546 /FL=gb:AL136669.1 gb:BC001852.1 gb:NM_017872.1 NM_017872 tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) THG1L 54974 NM_017872 /// XM_005265939 0006400 // tRNA modification // inferred from sequence or structural similarity /// 0008033 // tRNA processing // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0008193 // tRNA guanylyltransferase activity // inferred from direct assay /// 0008193 // tRNA guanylyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219123_at NM_014519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014519.1 /DEF=Homo sapiens zinc finger protein 232 (ZNF232), mRNA. /FEA=mRNA /GEN=ZNF232 /PROD=zinc finger protein 232 /DB_XREF=gi:7657704 /UG=Hs.279914 zinc finger protein 232 /FL=gb:NM_014519.1 NM_014519 zinc finger protein 232 ZNF232 7775 NM_014519 /// XM_005256792 /// XM_006721574 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219124_at NM_025115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025115.1 /DEF=Homo sapiens hypothetical protein FLJ23263 (FLJ23263), mRNA. /FEA=mRNA /GEN=FLJ23263 /PROD=hypothetical protein FLJ23263 /DB_XREF=gi:13376690 /UG=Hs.288716 hypothetical protein FLJ23263 /FL=gb:NM_025115.1 NM_025115 TELO2 interacting protein 2 TTI2 80185 NM_001102401 /// NM_001265581 /// NM_025115 0005488 // binding // inferred from electronic annotation 219125_s_at NM_018845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018845.1 /DEF=Homo sapiens stromal cell protein (LOC55974), mRNA. /FEA=mRNA /GEN=LOC55974 /PROD=stromal cell protein /DB_XREF=gi:10047123 /UG=Hs.292154 stromal cell protein /FL=gb:NM_018845.1 gb:AF126023.1 NM_018845 solute carrier family 50 (sugar efflux transporter), member 1 SLC50A1 55974 NM_001122837 /// NM_001122839 /// NM_001287586 /// NM_001287587 /// NM_001287588 /// NM_001287589 /// NM_001287590 /// NM_001287591 /// NM_001287592 /// NM_018845 /// XM_005245339 /// XM_005245340 /// XM_005245341 /// XM_005245342 /// XM_006711453 0006310 // DNA recombination // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042946 // glucoside transport // inferred from direct assay /// 0045815 // positive regulation of gene expression, epigenetic // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0042947 // glucoside transmembrane transporter activity // inferred from direct assay 219126_at NM_018288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018288.1 /DEF=Homo sapiens hypothetical protein FLJ10975 (FLJ10975), mRNA. /FEA=mRNA /GEN=FLJ10975 /PROD=hypothetical protein FLJ10975 /DB_XREF=gi:8922799 /UG=Hs.321578 hypothetical protein FLJ10975 /FL=gb:NM_018288.1 NM_018288 PHD finger protein 10 PHF10 55274 NM_018288 /// NM_133325 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0071564 // npBAF complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219127_at NM_024320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024320.1 /DEF=Homo sapiens hypothetical protein MGC11242 (MGC11242), mRNA. /FEA=mRNA /GEN=MGC11242 /PROD=hypothetical protein MGC11242 /DB_XREF=gi:13236560 /UG=Hs.36529 hypothetical protein MGC11242 /FL=gb:BC002865.1 gb:NM_024320.1 NM_024320 proline rich 15-like PRR15L 79170 NM_024320 /// XM_005257663 /// XM_005257664 /// XM_005257665 /// XM_005257666 219128_at NM_017880 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017880.1 /DEF=Homo sapiens hypothetical protein FLJ20558 (FLJ20558), mRNA. /FEA=mRNA /GEN=FLJ20558 /PROD=hypothetical protein FLJ20558 /DB_XREF=gi:8923527 /UG=Hs.38681 hypothetical protein FLJ20558 /FL=gb:AL136834.1 gb:BC002825.1 gb:BC005079.1 gb:NM_017880.1 NM_017880 chromosome 2 open reading frame 42 C2orf42 54980 NM_017880 /// XM_005264389 /// XM_005264390 /// XM_005264391 /// XR_244943 219129_s_at NM_024632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024632.1 /DEF=Homo sapiens hypothetical protein FLJ11526 (FLJ11526), mRNA. /FEA=mRNA /GEN=FLJ11526 /PROD=hypothetical protein FLJ11526 /DB_XREF=gi:13375861 /UG=Hs.38750 hypothetical protein FLJ11526 /FL=gb:NM_024632.1 NM_024632 SAP30-like SAP30L 79685 NM_001131062 /// NM_001131063 /// NM_024632 /// NR_024084 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219130_at NM_019083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019083.1 /DEF=Homo sapiens hypothetical protein (FLJ10287), mRNA. /FEA=mRNA /GEN=FLJ10287 /PROD=hypothetical protein FLJ11219 /DB_XREF=gi:11024703 /UG=Hs.40337 hypothetical protein /FL=gb:NM_019083.1 NM_019083 tRNA methyltransferase 13 homolog (S. cerevisiae) TRMT13 54482 NM_019083 /// XM_005270945 /// XM_005270946 /// XR_246273 /// XR_246274 /// XR_246275 /// XR_246276 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219131_at NM_013319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013319.1 /DEF=Homo sapiens transitional epithelia response protein (TERE1), mRNA. /FEA=mRNA /GEN=TERE1 /PROD=transitional epithelia response protein /DB_XREF=gi:7019550 /UG=Hs.40834 transitional epithelia response protein /FL=gb:BC004468.1 gb:AF117064.1 gb:NM_013319.1 NM_013319 UbiA prenyltransferase domain containing 1 UBIAD1 29914 NM_013319 /// XM_006710590 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from mutant phenotype /// 0042371 // vitamin K biosynthetic process // inferred from direct assay /// 0042371 // vitamin K biosynthetic process // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004659 // prenyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation 219132_at NM_021255 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021255.1 /DEF=Homo sapiens pellino (Drosophila) homolog 2 (PELI2), mRNA. /FEA=mRNA /GEN=PELI2 /PROD=pellino (Drosophila) homolog 2 /DB_XREF=gi:10864062 /UG=Hs.44038 pellino (Drosophila) homolog 2 /FL=gb:AF302502.1 gb:NM_021255.1 NM_021255 pellino E3 ubiquitin protein ligase family member 2 PELI2 57161 NM_021255 /// XM_005267890 /// XM_006720211 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 219133_at NM_017897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017897.1 /DEF=Homo sapiens hypothetical protein FLJ20604 (FLJ20604), mRNA. /FEA=mRNA /GEN=FLJ20604 /PROD=hypothetical protein FLJ20604 /DB_XREF=gi:8923558 /UG=Hs.55781 hypothetical protein FLJ20604 /FL=gb:NM_017897.1 NM_017897 3-oxoacyl-ACP synthase, mitochondrial OXSM 54995 NM_001145391 /// NM_017897 /// NR_026937 /// XM_006713216 /// XM_006713217 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0051790 // short-chain fatty acid biosynthetic process // inferred from direct assay /// 0051792 // medium-chain fatty acid biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype 0003824 // catalytic activity // inferred from electronic annotation /// 0004315 // 3-oxoacyl-[acyl-carrier-protein] synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 219134_at NM_022159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022159.1 /DEF=Homo sapiens ETL protein (ETL), mRNA. /FEA=mRNA /GEN=ETL /PROD=ETL protein /DB_XREF=gi:11545907 /UG=Hs.57958 EGF-TM7-latrophilin-related protein /FL=gb:AF192403.1 gb:NM_022159.1 NM_022159 EGF, latrophilin and seven transmembrane domain containing 1 ELTD1 64123 NM_022159 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 219135_s_at AL515916 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL515916 /FEA=EST /DB_XREF=gi:12779409 /DB_XREF=est:AL515916 /CLONE=CS0DA001YH18 (3 prime) /UG=Hs.58362 hypothetical protein FLJ12681 /FL=gb:NM_022773.1 AL515916 lipase maturation factor 1 LMF1 64788 NM_022773 /// NR_033645 /// NR_033646 /// NR_036442 /// XM_006720926 /// XM_006720927 /// XM_006720928 /// XM_006720929 /// XM_006720930 /// XR_429646 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0009306 // protein secretion // inferred from electronic annotation /// 0033578 // protein glycosylation in Golgi // inferred from electronic annotation /// 0034382 // chylomicron remnant clearance // inferred from electronic annotation /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from electronic annotation /// 0090207 // regulation of triglyceride metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219136_s_at NM_022773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022773.1 /DEF=Homo sapiens hypothetical protein FLJ12681 (FLJ12681), mRNA. /FEA=mRNA /GEN=FLJ12681 /PROD=hypothetical protein FLJ12681 /DB_XREF=gi:12232454 /UG=Hs.58362 hypothetical protein FLJ12681 /FL=gb:NM_022773.1 NM_022773 lipase maturation factor 1 LMF1 64788 NM_022773 /// NR_033645 /// NR_033646 /// NR_036442 /// XM_006720926 /// XM_006720927 /// XM_006720928 /// XM_006720929 /// XM_006720930 /// XR_429646 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0009306 // protein secretion // inferred from electronic annotation /// 0033578 // protein glycosylation in Golgi // inferred from electronic annotation /// 0034382 // chylomicron remnant clearance // inferred from electronic annotation /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from electronic annotation /// 0090207 // regulation of triglyceride metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219137_s_at NM_020194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020194.1 /DEF=Homo sapiens GL004 protein (GL004), mRNA. /FEA=mRNA /GEN=GL004 /PROD=GL004 protein /DB_XREF=gi:9910247 /UG=Hs.7045 GL004 protein /FL=gb:AF226049.1 gb:NM_020194.1 NM_020194 mitochondrial fission factor MFF 56947 NM_001277061 /// NM_001277062 /// NM_001277063 /// NM_001277064 /// NM_001277065 /// NM_001277066 /// NM_001277067 /// NM_001277068 /// NM_020194 /// NR_102266 /// XM_005246681 /// XM_005246682 /// XM_005246683 /// XM_005246684 /// XM_005246685 /// XM_005246686 /// XM_005246687 /// XM_005246688 /// XM_006712637 /// XM_006712638 /// XM_006712639 0000266 // mitochondrial fission // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0010821 // regulation of mitochondrion organization // inferred from mutant phenotype /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay /// 1900063 // regulation of peroxisome organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 219138_at BC000606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000606.1 /DEF=Homo sapiens, Similar to ribosomal protein L14, clone MGC:1644, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein L14 /DB_XREF=gi:12653648 /UG=Hs.738 ribosomal protein L14 /FL=gb:BC000606.1 gb:D87735.1 gb:NM_003973.1 BC000606 ribosomal protein L14 RPL14 9045 NM_001034996 /// NM_003973 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219139_s_at AF119868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF119868.1 /DEF=Homo sapiens PRO2222 mRNA, complete cds. /FEA=mRNA /PROD=PRO2222 /DB_XREF=gi:7770172 /UG=Hs.76461 retinol-binding protein 4, interstitial /FL=gb:AF119868.1 gb:NM_006744.2 AF119868 ciliary rootlet coiled-coil, rootletin pseudogene 3 CROCCP3 114819 NR_023386 0001523 // retinoid metabolic process // traceable author statement /// 0001654 // eye development // inferred from electronic annotation /// 0001654 // eye development // inferred from mutant phenotype /// 0001654 // eye development // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from mutant phenotype /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0034633 // retinol transport // inferred by curator /// 0034633 // retinol transport // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from mutant phenotype /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0048807 // female genitalia morphogenesis // inferred from electronic annotation /// 0048807 // female genitalia morphogenesis // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity /// 0051297 // centrosome organization // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from electronic annotation /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060068 // vagina development // inferred from electronic annotation /// 0060068 // vagina development // inferred from sequence or structural similarity /// 0060157 // urinary bladder development // inferred from electronic annotation /// 0060157 // urinary bladder development // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from direct assay /// 0019841 // retinol binding // inferred from electronic annotation /// 0034632 // retinol transporter activity // inferred by curator /// 0034632 // retinol transporter activity // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 219140_s_at NM_006744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006744.2 /DEF=Homo sapiens retinol-binding protein 4, interstitial (RBP4), mRNA. /FEA=mRNA /GEN=RBP4 /PROD=retinol-binding protein 4, interstitialprecursor /DB_XREF=gi:8400727 /UG=Hs.76461 retinol-binding protein 4, interstitial /FL=gb:AF119868.1 gb:NM_006744.2 NM_006744 retinol binding protein 4, plasma RBP4 5950 NM_006744 /// XM_005270023 0001523 // retinoid metabolic process // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001654 // eye development // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from mutant phenotype /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0034633 // retinol transport // inferred by curator /// 0042572 // retinol metabolic process // inferred from mutant phenotype /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0048807 // female genitalia morphogenesis // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050908 // detection of light stimulus involved in visual perception // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060068 // vagina development // inferred from sequence or structural similarity /// 0060157 // urinary bladder development // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from direct assay /// 0034632 // retinol transporter activity // inferred by curator /// 0036094 // small molecule binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 219141_s_at NM_017749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017749.1 /DEF=Homo sapiens hypothetical protein FLJ20294 (FLJ20294), mRNA. /FEA=mRNA /GEN=FLJ20294 /PROD=hypothetical protein FLJ20294 /DB_XREF=gi:8923272 /UG=Hs.7995 hypothetical protein FLJ20294 /FL=gb:NM_017749.1 NM_017749 autophagy/beclin-1 regulator 1 AMBRA1 55626 NM_001267782 /// NM_001267783 /// NM_017749 /// XM_005253009 /// XM_005253011 /// XM_005253012 /// XM_005253014 /// XM_006718259 /// XM_006718260 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219142_at NM_023940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023940.1 /DEF=Homo sapiens hypothetical protein MGC2827 (MGC2827), mRNA. /FEA=mRNA /GEN=MGC2827 /PROD=hypothetical protein MGC2827 /DB_XREF=gi:13027611 /UG=Hs.8035 hypothetical protein MGC2827 /FL=gb:BC001087.1 gb:BC001846.1 gb:NM_023940.1 NM_023940 RAS-like, family 11, member B RASL11B 65997 NM_023940 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 219143_s_at NM_017793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017793.1 /DEF=Homo sapiens hypothetical protein FLJ20374 (FLJ20374), mRNA. /FEA=mRNA /GEN=FLJ20374 /PROD=hypothetical protein FLJ20374 /DB_XREF=gi:8923354 /UG=Hs.8562 hypothetical protein FLJ20374 /FL=gb:NM_017793.1 NM_017793 ribonuclease P/MRP 25kDa subunit RPP25 54913 NM_017793 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219144_at NM_024025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024025.1 /DEF=Homo sapiens hypothetical protein MGC1136 (MGC1136), mRNA. /FEA=mRNA /GEN=MGC1136 /PROD=hypothetical protein MGC1136 /DB_XREF=gi:13128967 /UG=Hs.8719 hypothetical protein MGC1136 /FL=gb:BC001613.1 gb:BC003115.1 gb:NM_024025.1 NM_024025 dual specificity phosphatase 26 (putative) DUSP26 78986 NM_024025 /// XM_005273633 /// XM_006716395 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 1902310 // positive regulation of peptidyl-serine dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0002039 // p53 binding // inferred from physical interaction /// 0004647 // phosphoserine phosphatase activity // inferred from direct assay /// 0004647 // phosphoserine phosphatase activity // inferred from mutant phenotype /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 219145_at NM_024679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024679.1 /DEF=Homo sapiens hypothetical protein FLJ11939 (FLJ11939), mRNA. /FEA=mRNA /GEN=FLJ11939 /PROD=hypothetical protein FLJ11939 /DB_XREF=gi:13375947 /UG=Hs.94229 hypothetical protein FLJ11939 /FL=gb:NM_024679.1 NM_024679 latrophilin 1 LPHN1 22859 NM_001008701 /// NM_014921 /// XM_005259818 /// XM_005259819 /// XM_006722688 /// XM_006722689 /// XM_006722690 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016524 // latrotoxin receptor activity // inferred from sequence or structural similarity /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 219146_at NM_024683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024683.1 /DEF=Homo sapiens hypothetical protein FLJ22729 (FLJ22729), mRNA. /FEA=mRNA /GEN=FLJ22729 /PROD=hypothetical protein FLJ22729 /DB_XREF=gi:13375953 /UG=Hs.94891 hypothetical protein FLJ22729 /FL=gb:NM_024683.1 NM_024683 transcription elongation factor, mitochondrial TEFM 79736 NM_024683 /// XM_006722084 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006264 // mitochondrial DNA replication // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from direct assay /// 0030337 // DNA polymerase processivity factor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219147_s_at NM_017881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017881.1 /DEF=Homo sapiens hypothetical protein FLJ20559 (FLJ20559), mRNA. /FEA=mRNA /GEN=FLJ20559 /PROD=hypothetical protein FLJ20559 /DB_XREF=gi:8923529 /UG=Hs.98135 hypothetical protein FLJ20559 /FL=gb:BC001366.1 gb:NM_017881.1 NM_017881 nicotinamide riboside kinase 1 NMRK1 54981 NM_001127603 /// NM_017881 /// NR_023352 /// XM_006717162 /// XM_006717163 /// XM_006717164 /// XM_006717165 0006222 // UMP biosynthetic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019359 // nicotinamide nucleotide biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004849 // uridine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050262 // ribosylnicotinamide kinase activity // inferred from electronic annotation 219148_at NM_018492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018492.1 /DEF=Homo sapiens PDZ-binding kinase; T-cell originated protein kinase (TOPK), mRNA. /FEA=mRNA /GEN=TOPK /PROD=PDZ-binding kinase /DB_XREF=gi:8923876 /UG=Hs.104741 PDZ-binding kinase; T-cell originated protein kinase /FL=gb:AF189722.1 gb:AF237709.1 gb:NM_018492.1 gb:AB027249.1 gb:AB027250.1 NM_018492 PDZ binding kinase PBK 55872 NM_001278945 /// NM_018492 /// XM_006716368 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219149_x_at NM_016216 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016216.1 /DEF=Homo sapiens RNA lariat debranching enzyme (LOC51163), mRNA. /FEA=mRNA /GEN=LOC51163 /PROD=RNA lariat debranching enzyme /DB_XREF=gi:7705890 /UG=Hs.118194 RNA lariat debranching enzyme /FL=gb:AF180919.2 gb:NM_016216.1 NM_016216 debranching RNA lariats 1 DBR1 51163 NM_016216 0000375 // RNA splicing, via transesterification reactions // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay 0008419 // RNA lariat debranching enzyme activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219150_s_at NM_006869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006869.1 /DEF=Homo sapiens centaurin-alpha (GCS1L), mRNA. /FEA=mRNA /GEN=GCS1L /PROD=centaurin-alpha /DB_XREF=gi:6806912 /UG=Hs.135183 centaurin-alpha /FL=gb:AF082324.1 gb:NM_006869.1 NM_006869 ArfGAP with dual PH domains 1 ADAP1 11033 NM_001284308 /// NM_001284309 /// NM_001284310 /// NM_001284311 /// NM_006869 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219151_s_at NM_007081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007081.1 /DEF=Homo sapiens RAB, member of RAS oncogene family-like 2B (RABL2B), mRNA. /FEA=mRNA /GEN=RABL2B /PROD=RAB, member of RAS oncogene family-like 2B /DB_XREF=gi:5902039 /UG=Hs.145409 RAB, member of RAS oncogene family-like 2B /FL=gb:AF095352.1 gb:NM_007081.1 NM_007081 RAB, member of RAS oncogene family-like 2A /// RAB, member of RAS oncogene family-like 2B RABL2A /// RABL2B 11158 /// 11159 NM_001003789 /// NM_001130919 /// NM_001130920 /// NM_001130921 /// NM_001130922 /// NM_001130923 /// NM_007081 /// NM_007082 /// NM_013412 /// XM_005261899 /// XM_005261900 /// XM_005261901 /// XM_005263569 /// XM_005263570 /// XM_005263575 /// XM_005263576 /// XM_005263579 /// XM_005263582 /// XM_006712207 /// XM_006712208 /// XM_006712209 /// XM_006712210 /// XM_006712211 /// XM_006712212 /// XM_006712213 /// XM_006712214 /// XM_006712215 /// XM_006712216 /// XM_006712217 /// XM_006712218 /// XM_006712219 /// XM_006712220 /// XM_006712221 /// XM_006712222 /// XM_006724412 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 219152_at NM_015720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015720.1 /DEF=Homo sapiens endoglycan (PODLX2), mRNA. /FEA=mRNA /GEN=PODLX2 /PROD=endoglycan /DB_XREF=gi:7657464 /UG=Hs.145416 endoglycan /FL=gb:AF219137.1 gb:NM_015720.1 NM_015720 podocalyxin-like 2 PODXL2 50512 NM_015720 /// XM_006710151 0007155 // cell adhesion // inferred from electronic annotation /// 0050901 // leukocyte tethering or rolling // inferred from direct assay 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement 219153_s_at NM_024817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024817.1 /DEF=Homo sapiens hypothetical protein FLJ13710 (FLJ13710), mRNA. /FEA=mRNA /GEN=FLJ13710 /PROD=hypothetical protein FLJ13710 /DB_XREF=gi:13376209 /UG=Hs.170345 hypothetical protein FLJ13710 /FL=gb:NM_024817.1 NM_024817 thrombospondin, type I, domain containing 4 THSD4 79875 NM_001286429 /// NM_024817 /// XM_006720692 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219154_at NM_024714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024714.1 /DEF=Homo sapiens hypothetical protein FLJ12567 (FLJ12567), mRNA. /FEA=mRNA /GEN=FLJ12567 /PROD=hypothetical protein FLJ12567 /DB_XREF=gi:13376014 /UG=Hs.106525 hypothetical protein FLJ12567 /FL=gb:NM_024714.1 NM_024714 transmembrane protein 120B TMEM120B 144404 NM_001080825 /// XM_005253842 /// XM_005253843 /// XM_006719244 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219155_at NM_012417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012417.1 /DEF=Homo sapiens retinal degeneration B beta (RDGBB), mRNA. /FEA=mRNA /GEN=RDGBB /PROD=retinal degeneration B beta /DB_XREF=gi:6912623 /UG=Hs.109219 retinal degeneration B beta /FL=gb:AF171102.1 gb:NM_012417.1 NM_012417 phosphatidylinositol transfer protein, cytoplasmic 1 PITPNC1 26207 NM_012417 /// NM_181671 /// XM_005257216 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015914 // phospholipid transport // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // inferred from mutant phenotype 219156_at NM_018373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018373.1 /DEF=Homo sapiens hypothetical protein FLJ11271 (FLJ11271), mRNA. /FEA=mRNA /GEN=FLJ11271 /PROD=hypothetical protein FLJ11271 /DB_XREF=gi:8922963 /UG=Hs.109654 hypothetical protein FLJ11271 /FL=gb:NM_018373.1 NM_018373 synaptojanin 2 binding protein /// SYNJ2BP-COX16 readthrough SYNJ2BP /// SYNJ2BP-COX16 55333 /// 100529257 NM_001202547 /// NM_001202548 /// NM_001202549 /// NM_018373 0002092 // positive regulation of receptor internalization // inferred from electronic annotation /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from electronic annotation /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from electronic annotation /// 0048312 // intracellular distribution of mitochondria // inferred from electronic annotation /// 2000010 // positive regulation of protein localization to cell surface // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0070699 // type II activin receptor binding // inferred from electronic annotation 219157_at NM_007246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007246.1 /DEF=Homo sapiens kelch (Drosophila)-like 2 (Mayven) (KLHL2), mRNA. /FEA=mRNA /GEN=KLHL2 /PROD=kelch (Drosophila)-like 2 (Mayven) /DB_XREF=gi:6005702 /UG=Hs.122967 kelch (Drosophila)-like 2 (Mayven) /FL=gb:AF059569.1 gb:NM_007246.1 NM_007246 kelch-like family member 2 KLHL2 11275 NM_001161521 /// NM_001161522 /// NM_007246 /// XM_005262710 /// XM_006714074 0016567 // protein ubiquitination // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219158_s_at NM_025085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025085.1 /DEF=Homo sapiens hypothetical protein FLJ13340 (FLJ13340), mRNA. /FEA=mRNA /GEN=FLJ13340 /PROD=hypothetical protein FLJ13340 /DB_XREF=gi:13376639 /UG=Hs.125034 hypothetical protein FLJ13340 /FL=gb:AF327722.1 gb:NM_025085.1 NM_025085 N(alpha)-acetyltransferase 15, NatA auxiliary subunit NAA15 80155 NM_057175 /// XM_005263236 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031415 // NatA complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219159_s_at NM_021181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021181.2 /DEF=Homo sapiens 19A24 protein (LOC57823), mRNA. /FEA=mRNA /GEN=LOC57823 /PROD=19A24 protein /DB_XREF=gi:12711663 /UG=Hs.132906 19A24 protein /FL=gb:NM_021181.2 gb:AF291815.1 NM_021181 SLAM family member 7 SLAMF7 57823 NM_001282588 /// NM_001282589 /// NM_001282590 /// NM_001282591 /// NM_001282592 /// NM_001282593 /// NM_001282594 /// NM_001282595 /// NM_001282596 /// NM_021181 /// XM_005245386 /// XM_006711471 0007155 // cell adhesion // non-traceable author statement /// 0030101 // natural killer cell activation // non-traceable author statement /// 0032814 // regulation of natural killer cell activation // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219160_s_at NM_022894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022894.1 /DEF=Homo sapiens hypothetical protein FLJ12972 (FLJ12972), mRNA. /FEA=mRNA /GEN=FLJ12972 /PROD=hypothetical protein FLJ12972 /DB_XREF=gi:12597628 /UG=Hs.146123 hypothetical protein FLJ12972 /FL=gb:NM_022894.1 NM_022894 poly(A) polymerase gamma PAPOLG 64895 NM_022894 /// XM_005264500 /// XM_005264501 0006378 // mRNA polyadenylation // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0043631 // RNA polyadenylation // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from direct assay 219161_s_at NM_016951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016951.2 /DEF=Homo sapiens transmembrane proteolipid (HSPC224), mRNA. /FEA=mRNA /GEN=HSPC224 /PROD=transmembrane proteolipid /DB_XREF=gi:10092593 /UG=Hs.15159 chemokine-like factor, alternatively spliced /FL=gb:NM_016951.2 gb:BC004380.1 gb:AF057306.1 gb:AF151058.1 gb:AF135380.2 NM_016951 chemokine-like factor /// CKLF-CMTM1 readthrough CKLF /// CKLF-CMTM1 51192 /// 100529251 NM_001040138 /// NM_001040139 /// NM_001202509 /// NM_001204098 /// NM_001204099 /// NM_016326 /// NM_016951 /// NM_181640 /// NM_181641 0006935 // chemotaxis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay 219162_s_at NM_016050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016050.1 /DEF=Homo sapiens CGI-113 protein (LOC51017), mRNA. /FEA=mRNA /GEN=LOC51017 /PROD=CGI-113 protein /DB_XREF=gi:7705617 /UG=Hs.152738 CGI-113 protein /FL=gb:AF151871.1 gb:NM_016050.1 NM_016050 mitochondrial ribosomal protein L11 MRPL11 65003 NM_016050 /// NM_170738 /// NM_170739 /// NR_120588 /// NR_120589 /// XM_006718666 /// XR_247244 /// XR_247672 /// XR_252914 0006412 // translation // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219163_at NM_017656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017656.1 /DEF=Homo sapiens hypothetical protein FLJ20079 (FLJ20079), mRNA. /FEA=mRNA /GEN=FLJ20079 /PROD=hypothetical protein FLJ20079 /DB_XREF=gi:8923085 /UG=Hs.165948 hypothetical protein FLJ20079 /FL=gb:NM_017656.1 NM_017656 zinc finger protein 562 ZNF562 54811 NM_001130031 /// NM_001130032 /// NM_017656 /// XM_005259941 /// XM_005259942 /// XM_005259944 /// XM_005259945 /// XM_005259947 /// XM_005259950 /// XM_005259951 /// XM_005259952 /// XM_006722774 /// XM_006722775 /// XM_006722776 /// XM_006722777 /// XM_006722778 /// XM_006722779 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219164_s_at NM_018036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018036.1 /DEF=Homo sapiens hypothetical protein FLJ10242 (FLJ10242), mRNA. /FEA=mRNA /GEN=FLJ10242 /PROD=hypothetical protein FLJ10242 /DB_XREF=gi:8922304 /UG=Hs.168241 hypothetical protein FLJ10242 /FL=gb:NM_018036.1 NM_018036 autophagy related 2B ATG2B 55102 NM_018036 /// XM_006720187 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0044804 // nucleophagy // 0000407 // pre-autophagosomal structure // not recorded /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from electronic annotation 219165_at NM_021630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021630.1 /DEF=Homo sapiens PDZ-LIM protein mystique (LOC59346), mRNA. /FEA=mRNA /GEN=LOC59346 /PROD=PDZ-LIM protein mystique /DB_XREF=gi:11055999 /UG=Hs.19447 PDZ-LIM protein mystique /FL=gb:AY007729.1 gb:NM_021630.1 NM_021630 PDZ and LIM domain 2 (mystique) PDLIM2 64236 NM_021630 /// NM_176871 /// NM_198042 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031005 // filamin binding // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from electronic annotation 219166_at NM_018139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018139.1 /DEF=Homo sapiens hypothetical protein FLJ10563 (FLJ10563), mRNA. /FEA=mRNA /GEN=FLJ10563 /PROD=hypothetical protein FLJ10563 /DB_XREF=gi:8922518 /UG=Hs.265960 hypothetical protein FLJ10563 /FL=gb:NM_018139.1 NM_018139 dynein, axonemal, assembly factor 2 DNAAF2 55172 NM_001083908 /// NM_018139 0010033 // response to organic substance // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0060285 // cilium-dependent cell motility // inferred from mutant phenotype /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071973 // bacterial-type flagellum-dependent cell motility // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219167_at NM_016563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016563.1 /DEF=Homo sapiens Ris (LOC51285), mRNA. /FEA=mRNA /GEN=LOC51285 /PROD=Ris /DB_XREF=gi:7706094 /UG=Hs.27018 Ris /FL=gb:AF233588.1 gb:NM_016563.1 NM_016563 RAS-like, family 12 RASL12 51285 NM_016563 /// XM_005254433 /// XM_005254434 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219168_s_at NM_017701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017701.1 /DEF=Homo sapiens hypothetical protein FLJ20185 (FLJ20185), mRNA. /FEA=mRNA /GEN=FLJ20185 /PROD=hypothetical protein FLJ20185 /DB_XREF=gi:8923174 /UG=Hs.272972 hypothetical protein FLJ20185 /FL=gb:NM_017701.1 NM_017701 proline rich 5 (renal) PRR5 55615 NM_001017528 /// NM_001017529 /// NM_001017530 /// NM_001198721 /// NM_015366 /// NM_181333 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031932 // TORC2 complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219169_s_at NM_016020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016020.1 /DEF=Homo sapiens CGI-75 protein (LOC51106), mRNA. /FEA=mRNA /GEN=LOC51106 /PROD=CGI-75 protein /DB_XREF=gi:7705784 /UG=Hs.279908 CGI-75 protein /FL=gb:AF151833.1 gb:NM_016020.1 NM_016020 transcription factor B1, mitochondrial TFB1M 51106 NM_016020 /// XM_005267005 /// XM_005267006 0000154 // rRNA modification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000179 // rRNA (adenine-N6,N6-)-dimethyltransferase activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008649 // rRNA methyltransferase activity // inferred from electronic annotation /// 0016433 // rRNA (adenine) methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219170_at NM_024333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024333.1 /DEF=Homo sapiens hypothetical protein MGC3213 (MGC3213), mRNA. /FEA=mRNA /GEN=MGC3213 /PROD=hypothetical protein MGC3213 /DB_XREF=gi:13236584 /UG=Hs.28144 hypothetical protein MGC3213 /FL=gb:BC003124.1 gb:NM_024333.1 gb:AF316829.1 NM_024333 fibronectin type III and SPRY domain containing 1 FSD1 79187 NM_024333 /// XM_005259644 /// XM_006722886 /// XR_430155 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219171_s_at NM_007345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007345.1 /DEF=Homo sapiens zinc finger protein 236 (ZNF236), mRNA. /FEA=mRNA /GEN=ZNF236 /PROD=zinc finger protein 236 /DB_XREF=gi:10092585 /UG=Hs.283619 zinc finger protein 236 /FL=gb:NM_007345.1 gb:AF085243.1 NM_007345 zinc finger protein 236 ZNF236 7776 NM_007345 /// XM_005266762 /// XM_006722541 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219172_at NM_024954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024954.1 /DEF=Homo sapiens hypothetical protein FLJ11807 (FLJ11807), mRNA. /FEA=mRNA /GEN=FLJ11807 /PROD=hypothetical protein FLJ11807 /DB_XREF=gi:13376438 /UG=Hs.285813 hypothetical protein FLJ11807 /FL=gb:NM_024954.1 NM_024954 ubiquitin domain containing 1 UBTD1 80019 NM_024954 0005515 // protein binding // inferred from electronic annotation 219173_at NM_024957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024957.1 /DEF=Homo sapiens hypothetical protein FLJ22686 (FLJ22686), mRNA. /FEA=mRNA /GEN=FLJ22686 /PROD=hypothetical protein FLJ22686 /DB_XREF=gi:13376444 /UG=Hs.286035 hypothetical protein FLJ22686 /FL=gb:NM_024957.1 NM_024957 myosin XVB pseudogene MYO15B 80022 NM_001080847 /// NR_003587 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 219174_at NM_025103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025103.1 /DEF=Homo sapiens hypothetical protein FLJ22621 (FLJ22621), mRNA. /FEA=mRNA /GEN=FLJ22621 /PROD=hypothetical protein FLJ22621 /DB_XREF=gi:13376668 /UG=Hs.288617 hypothetical protein FLJ22621 /FL=gb:NM_025103.1 NM_025103 intraflagellar transport 74 homolog (Chlamydomonas) IFT74 80173 NM_001099222 /// NM_001099223 /// NM_001099224 /// NM_025103 0030030 // cell projection organization // inferred from electronic annotation /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // not recorded /// 0005929 // cilium // not recorded /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // not recorded /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from direct assay 219175_s_at NM_017836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017836.1 /DEF=Homo sapiens hypothetical protein FLJ20473 (FLJ20473), mRNA. /FEA=mRNA /GEN=FLJ20473 /PROD=hypothetical protein FLJ20473 /DB_XREF=gi:8923438 /UG=Hs.330592 hypothetical protein FLJ20473 /FL=gb:NM_017836.1 NM_017836 solute carrier family 41, member 3 SLC41A3 54946 NM_001008485 /// NM_001008486 /// NM_001008487 /// NM_001164475 /// NM_017836 /// XM_005247559 /// XM_005247560 /// XM_005247561 /// XM_005247562 /// XM_005247563 /// XM_005247564 /// XM_005247565 /// XM_006713681 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 219176_at NM_024520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024520.1 /DEF=Homo sapiens hypothetical protein FLJ22555 (FLJ22555), mRNA. /FEA=mRNA /GEN=FLJ22555 /PROD=hypothetical protein FLJ22555 /DB_XREF=gi:13375659 /UG=Hs.3592 hypothetical protein FLJ22555 /FL=gb:NM_024520.1 NM_024520 chromosome 2 open reading frame 47 C2orf47 79568 NM_024520 /// XM_005246852 /// XR_427111 0005739 // mitochondrion // inferred from electronic annotation 219177_at NM_018321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018321.1 /DEF=Homo sapiens hypothetical protein FLJ11100 (FLJ11100), mRNA. /FEA=mRNA /GEN=FLJ11100 /PROD=hypothetical protein FLJ11100 /DB_XREF=gi:8922864 /UG=Hs.38114 hypothetical protein FLJ11100 /FL=gb:NM_018321.1 NM_018321 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) BRIX1 55299 NM_018321 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 219178_at NM_024638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024638.1 /DEF=Homo sapiens hypothetical protein FLJ12960 (FLJ12960), mRNA. /FEA=mRNA /GEN=FLJ12960 /PROD=hypothetical protein FLJ12960 /DB_XREF=gi:13375871 /UG=Hs.45005 hypothetical protein FLJ12960 /FL=gb:NM_024638.1 NM_024638 queuine tRNA-ribosyltransferase domain containing 1 QTRTD1 79691 NM_001256835 /// NM_001256836 /// NM_001256837 /// NM_024638 /// XM_005247769 /// XM_005247770 /// XM_006713744 0006400 // tRNA modification // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008616 // queuosine biosynthetic process // inferred from electronic annotation /// 0008616 // queuosine biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from electronic annotation /// 0008479 // queuine tRNA-ribosyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219179_at NM_016651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016651.2 /DEF=Homo sapiens heptacellular carcinoma novel gene-3 protein (LOC51339), mRNA. /FEA=mRNA /GEN=LOC51339 /PROD=heptacellular carcinoma novel gene-3 protein /DB_XREF=gi:8393715 /UG=Hs.48950 heptacellular carcinoma novel gene-3 protein /FL=gb:AF251079.2 gb:NM_016651.2 NM_016651 dishevelled-binding antagonist of beta-catenin 1 DACT1 51339 NM_001079520 /// NM_016651 /// NR_046093 /// NR_046095 /// XM_006720166 /// XM_006720167 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from genetic interaction /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048619 // embryonic hindgut morphogenesis // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1900107 // regulation of nodal signaling pathway // inferred from direct assay /// 2000095 // regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from sequence or structural similarity /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay /// 0070097 // delta-catenin binding // inferred from sequence or structural similarity 219180_s_at AI817074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI817074 /FEA=EST /DB_XREF=gi:5436153 /DB_XREF=est:wj76f08.x1 /CLONE=IMAGE:2408775 /UG=Hs.5420 hypothetical protein FLJ20695 /FL=gb:NM_017929.1 AI817074 peroxisomal biogenesis factor 26 PEX26 55670 NM_001127649 /// NM_001199319 /// NM_017929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from direct assay /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0045046 // protein import into peroxisome membrane // inferred from electronic annotation 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005779 // integral component of peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 219181_at NM_006033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006033.1 /DEF=Homo sapiens lipase, endothelial (LIPG), mRNA. /FEA=mRNA /GEN=LIPG /PROD=endothelial lipase precursor /DB_XREF=gi:5174496 /UG=Hs.65370 lipase, endothelial /FL=gb:AF118767.1 gb:NM_006033.1 NM_006033 lipase, endothelial LIPG 9388 NM_006033 /// XM_005258390 0006629 // lipid metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // non-traceable author statement /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0050746 // regulation of lipoprotein metabolic process // inferred from electronic annotation /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from electronic annotation /// 0004620 // phospholipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0008970 // phosphatidylcholine 1-acylhydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 219182_at NM_024533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024533.1 /DEF=Homo sapiens hypothetical protein FLJ22167 (FLJ22167), mRNA. /FEA=mRNA /GEN=FLJ22167 /PROD=hypothetical protein FLJ22167 /DB_XREF=gi:13375685 /UG=Hs.6853 hypothetical protein FLJ22167 /FL=gb:NM_024533.1 NM_024533 transmembrane protein 231 TMEM231 79583 NM_001077416 /// NM_001077418 /// NR_074083 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity 219183_s_at NM_013385 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013385.2 /DEF=Homo sapiens pleckstrin homology, Sec7 and coiledcoil domains 4 (PSCD4), mRNA. /FEA=mRNA /GEN=PSCD4 /PROD=pleckstrin homology, Sec7 and coiledcoildomains 4 /DB_XREF=gi:8670549 /UG=Hs.7189 pleckstrin homology, Sec7 and coiledcoil domains 4 /FL=gb:AF075458.1 gb:NM_013385.2 NM_013385 cytohesin 4 CYTH4 27128 NM_013385 /// XR_430406 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 219184_x_at NM_013337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013337.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 22 (yeast) homolog (TIM22), mRNA. /FEA=mRNA /GEN=TIM22 /PROD=translocase of inner mitochondrial membrane 22(yeast) homolog /DB_XREF=gi:7019552 /UG=Hs.87595 translocase of inner mitochondrial membrane 22 (yeast) homolog /FL=gb:BC002324.1 gb:AF155330.1 gb:NM_013337.1 NM_013337 translocase of inner mitochondrial membrane 22 homolog (yeast) TIMM22 29928 NM_013337 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045039 // protein import into mitochondrial inner membrane // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015266 // protein channel activity // traceable author statement 219185_at NM_012241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012241.2 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5 (SIRT5), transcript variant 1, mRNA. /FEA=mRNA /GEN=SIRT5 /PROD=sirtuin 5, isoform 1 /DB_XREF=gi:13787213 /UG=Hs.8899 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5 /FL=gb:BC000126.1 gb:NM_012241.2 gb:AF083110.1 NM_012241 sirtuin 5 SIRT5 23408 NM_001193267 /// NM_001242827 /// NM_012241 /// NM_031244 /// XM_005248967 /// XM_005248968 /// XM_005248969 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0036047 // peptidyl-lysine demalonylation // inferred from direct assay /// 0036048 // protein desuccinylation // inferred from direct assay /// 0036049 // peptidyl-lysine desuccinylation // inferred from direct assay /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036054 // protein-malonyllysine demalonylase activity // inferred from direct assay /// 0036055 // protein-succinyllysine desuccinylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 219186_at NM_020224 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020224.1 /DEF=Homo sapiens hypothetical protein DKFZp547O146 (DKFZp547O146), mRNA. /FEA=mRNA /GEN=DKFZp547O146 /PROD=hypothetical protein DKFZp547O146 /DB_XREF=gi:9910203 /UG=Hs.91246 hypothetical protein DKFZp547O146 /FL=gb:NM_020224.1 NM_020224 zinc finger and BTB domain containing 7A ZBTB7A 51341 NM_015898 /// XM_005259570 /// XM_005259571 /// XM_005259572 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 219187_at NM_022110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022110.1 /DEF=Homo sapiens DIR1 protein (NG7), mRNA. /FEA=mRNA /GEN=NG7 /PROD=DIR1 protein /DB_XREF=gi:11545822 /UG=Hs.99134 FK506-binding protein like /FL=gb:NM_022110.1 gb:BC004168.1 NM_022110 FK506 binding protein like FKBPL 63943 NM_022110 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0009314 // response to radiation // non-traceable author statement /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded 0005634 // nucleus // /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded 219188_s_at NM_014067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014067.2 /DEF=Homo sapiens LRP16 protein (LRP16), mRNA. /FEA=mRNA /GEN=LRP16 /PROD=LRP16 protein /DB_XREF=gi:13569839 /UG=Hs.10824 LRP16 protein /FL=gb:BC000270.1 gb:BC003188.1 gb:AF202922.2 gb:NM_014067.2 NM_014067 MACRO domain containing 1 MACROD1 28992 NM_014067 /// XM_005273939 /// XM_005273940 /// XM_005273941 /// XM_006718521 /// XM_006718522 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0042278 // purine nucleoside metabolic process // inferred from direct assay /// 0051725 // protein de-ADP-ribosylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from direct assay /// 0019213 // deacetylase activity // inferred from direct assay 219189_at NM_024555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024555.1 /DEF=Homo sapiens f-box and leucine-rich repeat protein 6 (FBXL6), mRNA. /FEA=mRNA /GEN=FBXL6 /PROD=f-box and leucine-rich repeat protein 6 /DB_XREF=gi:13435140 /UG=Hs.12271 f-box and leucine-rich repeat protein 6 /FL=gb:NM_024555.1 NM_024555 F-box and leucine-rich repeat protein 6 FBXL6 26233 NM_012162 /// NM_024555 0006508 // proteolysis // traceable author statement /// 0016567 // protein ubiquitination // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219190_s_at NM_017629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017629.1 /DEF=Homo sapiens hypothetical protein FLJ20033 (FLJ20033), mRNA. /FEA=mRNA /GEN=FLJ20033 /PROD=hypothetical protein FLJ20033 /DB_XREF=gi:8923033 /UG=Hs.134757 hypothetical protein FLJ20033 /FL=gb:NM_017629.1 NM_017629 argonaute RISC catalytic component 4 AGO4 192670 NM_017629 /// XM_005270578 /// XM_005270579 /// XR_246243 /// XR_246244 0006402 // mRNA catabolic process // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0035068 // micro-ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from electronic annotation 219191_s_at NM_016293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016293.1 /DEF=Homo sapiens bridging integrator 2 (BIN2), mRNA. /FEA=mRNA /GEN=BIN2 /PROD=breast cancer associated protein BRAP1 /DB_XREF=gi:7706486 /UG=Hs.14770 bridging integrator 2 /FL=gb:AF146531.1 gb:AB032698.1 gb:NM_016187.1 gb:NM_016293.1 NM_016293 bridging integrator 2 BIN2 51411 NM_001290007 /// NM_001290008 /// NM_001290009 /// NM_016293 /// XM_005268957 /// XM_005268958 0006911 // phagocytosis, engulfment // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0071800 // podosome assembly // inferred from mutant phenotype /// 0097320 // membrane tubulation // inferred from direct assay 0001891 // phagocytic cup // inferred from direct assay /// 0002102 // podosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 219192_at NM_018449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018449.1 /DEF=Homo sapiens AD-012 protein (LOC55833), mRNA. /FEA=mRNA /GEN=LOC55833 /PROD=AD-012 protein /DB_XREF=gi:8923858 /UG=Hs.14953 AD-012 protein /FL=gb:AF157327.1 gb:NM_018449.1 NM_018449 ubiquitin associated protein 2 UBAP2 55833 NM_001282529 /// NM_001282530 /// NM_018449 /// NM_020867 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219193_at NM_018034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018034.1 /DEF=Homo sapiens hypothetical protein FLJ10233 (FLJ10233), mRNA. /FEA=mRNA /GEN=FLJ10233 /PROD=hypothetical protein FLJ10233 /DB_XREF=gi:8922300 /UG=Hs.16079 hypothetical protein FLJ10233 /FL=gb:NM_018034.1 NM_018034 WD repeat domain 70 WDR70 55100 NM_018034 /// XM_005248318 /// XM_006714478 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 219194_at NM_017893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017893.1 /DEF=Homo sapiens KIAA1619 protein (KIAA1619), mRNA. /FEA=mRNA /GEN=KIAA1619 /PROD=KIAA1619 protein /DB_XREF=gi:8923550 /UG=Hs.169549 KIAA1619 protein /FL=gb:NM_017893.1 NM_017893 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G SEMA4G 57715 NM_001203244 /// NM_017893 /// XM_005270008 /// XM_005270009 /// XM_005270010 /// XR_246101 /// XR_428710 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219195_at NM_013261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013261.1 /DEF=Homo sapiens peroxisome proliferative activated receptor, gamma, coactivator 1 (PPARGC1), mRNA. /FEA=mRNA /GEN=PPARGC1 /PROD=peroxisome proliferative activated receptor,gamma, coactivator 1 /DB_XREF=gi:7019498 /UG=Hs.198468 peroxisome proliferative activated receptor, gamma, coactivator 1 /FL=gb:AF159714.1 gb:AF186379.1 gb:AF106698.1 gb:NM_013261.1 NM_013261 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha PPARGC1A 10891 NM_013261 /// XM_005248130 /// XM_005248131 /// XM_005248132 /// XM_005248134 0001659 // temperature homeostasis // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001678 // cellular glucose homeostasis // non-traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007005 // mitochondrion organization // non-traceable author statement /// 0007586 // digestion // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010822 // positive regulation of mitochondrion organization // inferred from sequence or structural similarity /// 0010941 // regulation of cell death // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0014850 // response to muscle activity // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // non-traceable author statement /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035066 // positive regulation of histone acetylation // traceable author statement /// 0036273 // response to statin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // non-traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043201 // response to leucine // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045333 // cellular respiration // traceable author statement /// 0045722 // positive regulation of gluconeogenesis // traceable author statement /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046321 // positive regulation of fatty acid oxidation // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // traceable author statement /// 0050873 // brown fat cell differentiation // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051552 // flavone metabolic process // inferred from electronic annotation /// 0070997 // neuron death // inferred from direct assay /// 0071250 // cellular response to nitrite // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071871 // response to epinephrine // inferred from electronic annotation /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from electronic annotation /// 1901857 // positive regulation of cellular respiration // inferred from electronic annotation /// 1901860 // positive regulation of mitochondrial DNA metabolic process // inferred from electronic annotation /// 1901863 // positive regulation of muscle tissue development // inferred from electronic annotation /// 2000272 // negative regulation of receptor activity // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from electronic annotation /// 2000507 // positive regulation of energy homeostasis // inferred from sequence or structural similarity /// 2001171 // positive regulation of ATP biosynthetic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement 219196_at NM_013243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013243.1 /DEF=Homo sapiens secretogranin III (SCG3), mRNA. /FEA=mRNA /GEN=SCG3 /PROD=secretogranin III /DB_XREF=gi:7019522 /UG=Hs.22215 secretogranin III /FL=gb:AF078851.1 gb:NM_013243.1 NM_013243 secretogranin III SCG3 29106 NM_001165257 /// NM_013243 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 219197_s_at AI424243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI424243 /FEA=EST /DB_XREF=gi:4270174 /DB_XREF=est:te95c06.x1 /CLONE=IMAGE:2094442 /UG=Hs.222399 CEGP1 protein /FL=gb:NM_020974.1 AI424243 signal peptide, CUB domain, EGF-like 2 SCUBE2 57758 NM_001170690 /// NM_020974 /// XM_005253032 /// XM_005253033 /// XM_005253034 /// XM_005253035 /// XM_005253036 /// XM_005253037 /// XM_006718268 0005576 // extracellular region // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219198_at NM_012204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012204.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 4 (90kD) (GTF3C4), mRNA. /FEA=mRNA /GEN=GTF3C4 /PROD=general transcription factor IIIC, polypeptide 4(90kD) /DB_XREF=gi:6912399 /UG=Hs.22302 general transcription factor IIIC, polypeptide 4 (90kD) /FL=gb:AF142328.1 gb:NM_012204.1 NM_012204 general transcription factor IIIC, polypeptide 4, 90kDa GTF3C4 9329 NM_012204 0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016573 // histone acetylation // inferred from electronic annotation /// 0016573 // histone acetylation // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator /// 0043085 // positive regulation of catalytic activity // traceable author statement 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred by curator /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 219199_at NM_014423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014423.1 /DEF=Homo sapiens ALL1 fused gene from 5q31 (AF5Q31), mRNA. /FEA=mRNA /GEN=AF5Q31 /PROD=ALL1 fused gene from 5q31 /DB_XREF=gi:7656878 /UG=Hs.231967 ALL1 fused gene from 5q31 /FL=gb:AF197927.1 gb:NM_014423.1 NM_014423 AF4/FMR2 family, member 4 AFF4 27125 NM_014423 /// XM_005271963 /// XM_005271964 /// XM_006714587 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219200_at NM_024091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024091.1 /DEF=Homo sapiens hypothetical protein MGC5297 (MGC5297), mRNA. /FEA=mRNA /GEN=MGC5297 /PROD=hypothetical protein MGC5297 /DB_XREF=gi:13129089 /UG=Hs.23856 hypothetical protein MGC5297 /FL=gb:BC001295.1 gb:NM_024091.1 NM_024091 FAST kinase domains 3 FASTKD3 79072 NM_024091 /// NR_036553 /// NR_073608 /// XM_006714498 /// XR_427664 0006468 // protein phosphorylation // inferred from electronic annotation /// 0045333 // cellular respiration // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219201_s_at NM_020648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020648.1 /DEF=Homo sapiens twisted gastrulation (TSG), mRNA. /FEA=mRNA /GEN=TSG /PROD=twisted gastrulation /DB_XREF=gi:10190663 /UG=Hs.247302 twisted gastrulation /FL=gb:NM_020648.1 gb:AF196834.1 gb:AF294628.1 NM_020648 twisted gastrulation BMP signaling modulator 1 TWSG1 57045 NM_020648 0001503 // ossification // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219202_at NM_024599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024599.1 /DEF=Homo sapiens hypothetical protein FLJ22341 (FLJ22341), mRNA. /FEA=mRNA /GEN=FLJ22341 /PROD=hypothetical protein FLJ22341 /DB_XREF=gi:13375798 /UG=Hs.25485 hypothetical protein FLJ22341 /FL=gb:NM_024599.1 NM_024599 rhomboid 5 homolog 2 (Drosophila) RHBDF2 79651 NM_001005498 /// NM_024599 /// XM_005257669 /// XM_005257670 /// XM_005257672 /// XM_006722079 /// XM_006722080 /// XM_006722081 /// XM_006722082 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 219203_at NM_016049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016049.1 /DEF=Homo sapiens CGI-112 protein (LOC51016), mRNA. /FEA=mRNA /GEN=LOC51016 /PROD=CGI-112 protein /DB_XREF=gi:7705615 /UG=Hs.271614 CGI-112 protein /FL=gb:BC002491.1 gb:AF151870.1 gb:NM_016049.1 NM_016049 ER membrane protein complex subunit 9 EMC9 51016 NM_016049 /// XM_005267721 /// XR_245688 0005737 // cytoplasm // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 219204_s_at NM_021947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021947.1 /DEF=Homo sapiens serine racemase (SRR), mRNA. /FEA=mRNA /GEN=SRR /PROD=serine racemase /DB_XREF=gi:11345491 /UG=Hs.27335 serine racemase /FL=gb:AF169974.1 gb:NM_021947.1 NM_021947 serine racemase SRR 63826 NM_021947 /// XM_006721565 /// XM_006721566 /// XM_006721567 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009069 // serine family amino acid metabolic process // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0042493 // response to drug // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from direct assay /// 0043278 // response to morphine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0070178 // D-serine metabolic process // inferred from direct assay /// 0070179 // D-serine biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003941 // L-serine ammonia-lyase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008721 // D-serine ammonia-lyase activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from sequence or structural similarity /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0018114 // threonine racemase activity // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from sequence or structural similarity /// 0030378 // serine racemase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219205_at NM_021947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021947.1 /DEF=Homo sapiens serine racemase (SRR), mRNA. /FEA=mRNA /GEN=SRR /PROD=serine racemase /DB_XREF=gi:11345491 /UG=Hs.27335 serine racemase /FL=gb:AF169974.1 gb:NM_021947.1 NM_021947 serine racemase SRR 63826 NM_021947 /// XM_006721565 /// XM_006721566 /// XM_006721567 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009069 // serine family amino acid metabolic process // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0042493 // response to drug // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from direct assay /// 0043278 // response to morphine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity /// 0070178 // D-serine metabolic process // inferred from direct assay /// 0070179 // D-serine biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003941 // L-serine ammonia-lyase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008721 // D-serine ammonia-lyase activity // inferred from electronic annotation /// 0016594 // glycine binding // inferred from sequence or structural similarity /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0018114 // threonine racemase activity // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from sequence or structural similarity /// 0030378 // serine racemase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219206_x_at NM_016056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016056.1 /DEF=Homo sapiens CGI-119 protein (LOC51643), mRNA. /FEA=mRNA /GEN=LOC51643 /PROD=CGI-119 protein /DB_XREF=gi:7706334 /UG=Hs.283670 CGI-119 protein /FL=gb:AF182041.1 gb:AF151877.1 gb:AF113127.1 gb:AF161526.1 gb:NM_016056.1 NM_016056 transmembrane BAX inhibitor motif containing 4 TMBIM4 51643 NM_001282606 /// NM_001282609 /// NM_001282610 /// NM_016056 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0050848 // regulation of calcium-mediated signaling // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219207_at NM_025083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025083.1 /DEF=Homo sapiens hypothetical protein FLJ21128 (FLJ21128), mRNA. /FEA=mRNA /GEN=FLJ21128 /PROD=hypothetical protein FLJ21128 /DB_XREF=gi:13376637 /UG=Hs.288389 hypothetical protein FLJ21128 /FL=gb:NM_025083.1 NM_025083 enhancer of mRNA decapping 3 EDC3 80153 NM_001142443 /// NM_001142444 /// NM_025083 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 219208_at NM_025133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025133.1 /DEF=Homo sapiens hypothetical protein FLJ12673 (FLJ12673), mRNA. /FEA=mRNA /GEN=FLJ12673 /PROD=hypothetical protein FLJ12673 /DB_XREF=gi:13376712 /UG=Hs.288836 hypothetical protein FLJ12673 /FL=gb:NM_025133.1 NM_025133 F-box protein 11 FBXO11 80204 NM_001190274 /// NM_012167 /// NM_018693 /// NM_025133 /// XM_005264572 /// XM_005264573 /// XM_005264574 0006464 // cellular protein modification process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0035246 // peptidyl-arginine N-methylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016274 // protein-arginine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219209_at NM_022168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022168.1 /DEF=Homo sapiens melanoma differentiation associated protein-5 (MDA5), mRNA. /FEA=mRNA /GEN=MDA5 /PROD=melanoma differentiation associated protein-5 /DB_XREF=gi:11545921 /UG=Hs.293591 melanoma differentiation associated protein-5 /FL=gb:AF095844.1 gb:NM_022168.1 gb:AY017378.1 NM_022168 interferon induced with helicase C domain 1 IFIH1 64135 NM_022168 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009597 // detection of virus // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032727 // positive regulation of interferon-alpha production // inferred from mutant phenotype /// 0032727 // positive regulation of interferon-alpha production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034344 // regulation of type III interferon production // traceable author statement /// 0039528 // cytoplasmic pattern recognition receptor signaling pathway in response to virus // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219210_s_at NM_016530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016530.1 /DEF=Homo sapiens RAB-8b protein (LOC51762), mRNA. /FEA=mRNA /GEN=LOC51762 /PROD=RAB-8b protein /DB_XREF=gi:7706562 /UG=Hs.321245 RAB-8b protein /FL=gb:AB038995.1 gb:NM_016530.1 NM_016530 RAB8B, member RAS oncogene family RAB8B 51762 NM_016530 /// XM_006720569 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0031346 // positive regulation of cell projection organization // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from sequence or structural similarity /// 0045046 // protein import into peroxisome membrane // inferred from direct assay /// 0051461 // positive regulation of corticotropin secretion // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0051286 // cell tip // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0030911 // TPR domain binding // inferred from electronic annotation 219211_at NM_017414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017414.1 /DEF=Homo sapiens ubiquitin specific protease 18 (USP18), mRNA. /FEA=mRNA /GEN=USP18 /PROD=ubiquitin specific protease 18 /DB_XREF=gi:8394518 /UG=Hs.38260 ubiquitin specific protease 18 /FL=gb:AL136690.1 gb:AF176642.2 gb:NM_017414.1 NM_017414 ubiquitin specific peptidase 18 USP18 11274 NM_017414 /// XM_006724074 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 219212_at NM_016299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016299.1 /DEF=Homo sapiens heat shock protein hsp70-related protein (LOC51182), mRNA. /FEA=mRNA /GEN=LOC51182 /PROD=heat shock protein hsp70-related protein /DB_XREF=gi:10047093 /UG=Hs.44581 heat shock protein hsp70-related protein /FL=gb:NM_016299.1 gb:AF112210.1 gb:AF143723.1 NM_016299 heat shock 70kDa protein 14 HSPA14 51182 NM_001037538 /// NM_001278205 /// NM_016299 /// NR_103464 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0051083 // 'de novo' cotranslational protein folding // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005840 // ribosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 219213_at NM_021219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021219.1 /DEF=Homo sapiens vascular endothelial junction-associated molecule (VE-JAM), mRNA. /FEA=mRNA /GEN=VE-JAM /PROD=vascular endothelial junction-associatedmolecule /DB_XREF=gi:10864028 /UG=Hs.54650 vascular endothelial junction-associated molecule /FL=gb:NM_021219.1 gb:AY016009.1 gb:AF255910.1 NM_021219 junctional adhesion molecule 2 JAM2 58494 NM_001270407 /// NM_001270408 /// NM_021219 /// NR_072999 /// XM_006724037 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 219214_s_at NM_021163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021163.1 /DEF=Homo sapiens RB-associated KRAB repressor (RBAK), mRNA. /FEA=mRNA /GEN=RBAK /PROD=RB-associated KRAB repressor /DB_XREF=gi:13430849 /UG=Hs.7222 RB-associated KRAB repressor /FL=gb:NM_021163.1 gb:AF226869.1 NM_021163 5', 3'-nucleotidase, cytosolic NT5C 30833 NM_001252377 /// NM_014595 /// NR_045513 /// XM_006721850 /// XM_006721851 /// XR_429885 /// XR_429886 /// XR_429887 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009223 // pyrimidine deoxyribonucleotide catabolic process // inferred from direct assay /// 0009264 // deoxyribonucleotide catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008252 // nucleotidase activity // inferred from direct assay /// 0008253 // 5'-nucleotidase activity // not recorded /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019103 // pyrimidine nucleotide binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219215_s_at NM_017767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017767.1 /DEF=Homo sapiens hypothetical protein FLJ20327 (FLJ20327), mRNA. /FEA=mRNA /GEN=FLJ20327 /PROD=hypothetical protein FLJ20327 /DB_XREF=gi:8923304 /UG=Hs.72289 hypothetical protein FLJ20327 /FL=gb:BC001688.1 gb:NM_017767.1 NM_017767 solute carrier family 39 (zinc transporter), member 4 SLC39A4 55630 NM_001280557 /// NM_017767 /// NM_130849 /// XM_006716599 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034224 // cellular response to zinc ion starvation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from electronic annotation /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 219216_at NM_019002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019002.1 /DEF=Homo sapiens ETAA16 protein (ETAA16), mRNA. /FEA=mRNA /GEN=ETAA16 /PROD=ETAA16 protein /DB_XREF=gi:9506580 /UG=Hs.82664 ETAA16 protein /FL=gb:NM_019002.1 NM_019002 Ewing tumor-associated antigen 1 ETAA1 54465 NM_019002 /// XM_005264374 /// XM_005264375 /// XM_005264376 /// XM_005264377 /// XM_005264378 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 219217_at NM_024678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024678.1 /DEF=Homo sapiens hypothetical protein FLJ23441 (FLJ23441), mRNA. /FEA=mRNA /GEN=FLJ23441 /PROD=hypothetical protein FLJ23441 /DB_XREF=gi:13375945 /UG=Hs.90012 hypothetical protein FLJ23441 /FL=gb:NM_024678.1 NM_024678 asparaginyl-tRNA synthetase 2, mitochondrial (putative) NARS2 79731 NM_001243251 /// NM_024678 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006421 // asparaginyl-tRNA aminoacylation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004816 // asparagine-tRNA ligase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 219218_at NM_024696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024696.1 /DEF=Homo sapiens hypothetical protein FLJ23058 (FLJ23058), mRNA. /FEA=mRNA /GEN=FLJ23058 /PROD=hypothetical protein FLJ23058 /DB_XREF=gi:13375978 /UG=Hs.98968 hypothetical protein FLJ23058 /FL=gb:NM_024696.1 NM_024696 BAH domain and coiled-coil containing 1 BAHCC1 57597 NM_001080519 /// NM_001291324 /// NM_024696 /// XM_006721988 /// XM_006721989 /// XM_006721990 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 219219_at NM_017854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017854.1 /DEF=Homo sapiens hypothetical protein FLJ20512 (FLJ20512), mRNA. /FEA=mRNA /GEN=FLJ20512 /PROD=hypothetical protein FLJ20512 /DB_XREF=gi:8923476 /UG=Hs.105606 hypothetical protein FLJ20512 /FL=gb:BC002907.1 gb:NM_017854.1 NM_017854 transmembrane protein 160 TMEM160 54958 NM_017854 /// XM_005259027 /// XM_006723253 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219220_x_at NM_020191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020191.1 /DEF=Homo sapiens GK002 protein (GK002), mRNA. /FEA=mRNA /GEN=GK002 /PROD=GK002 protein /DB_XREF=gi:9910243 /UG=Hs.107127 GK002 protein; gibt protein; chromosome 3 open reading frame 5 /FL=gb:AF321613.1 gb:AF226045.1 gb:NM_020191.1 NM_020191 mitochondrial ribosomal protein S22 MRPS22 56945 NM_020191 /// XM_005247640 /// XM_006713703 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay 219221_at NM_024724 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024724.1 /DEF=Homo sapiens hypothetical protein FLJ22332 (FLJ22332), mRNA. /FEA=mRNA /GEN=FLJ22332 /PROD=hypothetical protein FLJ22332 /DB_XREF=gi:13376033 /UG=Hs.111092 hypothetical protein FLJ22332 /FL=gb:NM_024724.1 NM_024724 zinc finger and BTB domain containing 38 ZBTB38 253461 NM_001080412 /// NM_152535 /// XM_005247255 /// XM_005247256 /// XM_005247257 /// XM_005247258 /// XM_005247261 /// XM_005247262 /// XM_005247263 /// XM_006713559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0072562 // blood microparticle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219222_at NM_022128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022128.1 /DEF=Homo sapiens ribokinase (RBSK), mRNA. /FEA=mRNA /GEN=RBSK /PROD=ribokinase /DB_XREF=gi:11545854 /UG=Hs.11916 ribokinase /FL=gb:NM_022128.1 NM_022128 ribokinase RBKS 64080 NM_001287580 /// NM_022128 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006014 // D-ribose metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019303 // D-ribose catabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004747 // ribokinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 219223_at NM_017586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017586.1 /DEF=Homo sapiens chromosome 9 open reading frame 7 (C9ORF7), mRNA. /FEA=mRNA /GEN=C9ORF7 /PROD=chromosome 9 open reading frame 7 /DB_XREF=gi:8922115 /UG=Hs.119285 chromosome 9 open reading frame 7 /FL=gb:NM_017586.1 NM_017586 calcium channel flower domain containing 1 CACFD1 11094 NM_001135775 /// NM_001242369 /// NM_001242370 /// NM_017586 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from electronic annotation 0005262 // calcium channel activity // inferred from electronic annotation 219224_x_at NM_024741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024741.1 /DEF=Homo sapiens hypothetical protein FLJ12827 (FLJ12827), mRNA. /FEA=mRNA /GEN=FLJ12827 /PROD=hypothetical protein FLJ12827 /DB_XREF=gi:13376063 /UG=Hs.121590 hypothetical protein FLJ12827 /FL=gb:NM_024741.1 gb:AF346626.1 NM_024741 zinc finger protein 408 ZNF408 79797 NM_001184751 /// NM_024741 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219225_at NM_024554 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024554.1 /DEF=Homo sapiens hypothetical protein FLJ11413 (FLJ11413), mRNA. /FEA=mRNA /GEN=FLJ11413 /PROD=hypothetical protein FLJ11413 /DB_XREF=gi:13375718 /UG=Hs.12247 hypothetical protein FLJ11413 /FL=gb:NM_024554.1 NM_024554 piggyBac transposable element derived 5 PGBD5 79605 NM_001258311 /// NM_024554 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219226_at NM_016507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016507.1 /DEF=Homo sapiens CDC2-related protein kinase 7 (CrkRS), mRNA. /FEA=mRNA /GEN=CrkRS /PROD=CDC2-related protein kinase 7 /DB_XREF=gi:7706548 /UG=Hs.123073 CDC2-related protein kinase 7 /FL=gb:AF227198.1 gb:NM_016507.1 NM_016507 cyclin-dependent kinase 12 CDK12 51755 NM_015083 /// NM_016507 /// XM_005257456 /// XM_005257458 /// XR_429896 /// XR_429897 /// XR_429898 /// XR_429899 /// XR_429900 /// XR_429901 /// XR_429902 /// XR_429903 /// XR_429904 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043405 // regulation of MAP kinase activity // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0070816 // phosphorylation of RNA polymerase II C-terminal domain // inferred from mutant phenotype 0002944 // cyclin K-CDK12 complex // inferred from physical interaction /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019908 // nuclear cyclin-dependent protein kinase holoenzyme complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from mutant phenotype /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 219227_at NM_024565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024565.1 /DEF=Homo sapiens hypothetical protein FLJ14166 (FLJ14166), mRNA. /FEA=mRNA /GEN=FLJ14166 /PROD=hypothetical protein FLJ14166 /DB_XREF=gi:13375734 /UG=Hs.14070 hypothetical protein FLJ14166 /FL=gb:NM_024565.1 NM_024565 cyclin J-like CCNJL 79616 NM_024565 /// XM_005265982 /// XM_006714917 /// XM_006714918 /// XR_427810 /// XR_427811 0005634 // nucleus // inferred from electronic annotation 219228_at NM_018555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018555.2 /DEF=Homo sapiens C2H2-like zinc finger protein (ZNF361), mRNA. /FEA=mRNA /GEN=ZNF361 /PROD=C2H2-like zinc finger protein /DB_XREF=gi:10092612 /UG=Hs.147644 zinc finger protein 331 /FL=gb:AF251515.2 gb:NM_018555.2 gb:AF272148.1 NM_018555 zinc finger protein 331 ZNF331 55422 NM_001079906 /// NM_001079907 /// NM_001253798 /// NM_001253799 /// NM_001253800 /// NM_001253801 /// NM_018555 /// XM_005259040 /// XM_006723259 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219229_at NM_013272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013272.2 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 11 (SLC21A11), mRNA. /FEA=mRNA /GEN=SLC21A11 /PROD=solute carrier family 21 (organic aniontransporter), member 11 /DB_XREF=gi:7706713 /UG=Hs.14805 solute carrier family 21 (organic anion transporter), member 11 /FL=gb:AF205074.1 gb:AF187816.1 gb:AB031050.2 gb:NM_013272.2 NM_013272 solute carrier organic anion transporter family, member 3A1 SLCO3A1 28232 NM_001145044 /// NM_013272 /// XM_005254889 /// XM_005254891 /// XM_006720472 /// XR_429450 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219230_at NM_018286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018286.1 /DEF=Homo sapiens hypothetical protein FLJ10970 (FLJ10970), mRNA. /FEA=mRNA /GEN=FLJ10970 /PROD=hypothetical protein FLJ10970 /DB_XREF=gi:8922795 /UG=Hs.173233 hypothetical protein FLJ10970 /FL=gb:NM_018286.1 NM_018286 transmembrane protein 100 TMEM100 55273 NM_001099640 /// NM_018286 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from sequence or structural similarity /// 0060842 // arterial endothelial cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043204 // perikaryon // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 219231_at NM_024831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024831.1 /DEF=Homo sapiens hypothetical protein FLJ22995 (FLJ22995), mRNA. /FEA=mRNA /GEN=FLJ22995 /PROD=hypothetical protein FLJ22995 /DB_XREF=gi:13376235 /UG=Hs.179909 hypothetical protein FLJ22995 /FL=gb:NM_024831.1 NM_024831 trimethylguanosine synthase 1 TGS1 96764 NM_024831 /// XM_005251328 /// XM_006716485 /// XM_006716486 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0001510 // RNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009452 // 7-methylguanosine RNA capping // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0022613 // ribonucleoprotein complex biogenesis // inferred by curator /// 0032259 // methylation // inferred from electronic annotation /// 0034660 // ncRNA metabolic process // traceable author statement /// 0036261 // 7-methylguanosine cap hypermethylation // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071167 // ribonucleoprotein complex import into nucleus // inferred by curator 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred by curator 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0071164 // RNA trimethylguanosine synthase activity // inferred from direct assay 219232_s_at NM_022073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022073.1 /DEF=Homo sapiens hypothetical protein FLJ21620 (FLJ21620), mRNA. /FEA=mRNA /GEN=FLJ21620 /PROD=hypothetical protein FLJ21620 /DB_XREF=gi:11545786 /UG=Hs.18878 hypothetical protein FLJ21620 /FL=gb:NM_022073.1 NM_022073 egl-9 family hypoxia-inducible factor 3 EGLN3 112399 NM_022073 /// XM_006720015 0001666 // response to hypoxia // inferred from expression pattern /// 0006915 // apoptotic process // inferred from expression pattern /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from expression pattern /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0018126 // protein hydroxylation // inferred from direct assay /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from expression pattern /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 219233_s_at NM_018530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018530.1 /DEF=Homo sapiens hypothetical protein PRO2521 (PRO2521), mRNA. /FEA=mRNA /GEN=PRO2521 /PROD=hypothetical protein PRO2521 /DB_XREF=gi:8924175 /UG=Hs.19054 hypothetical protein PRO2521 /FL=gb:AF119884.1 gb:NM_018530.1 NM_018530 gasdermin B GSDMB 55876 NM_001042471 /// NM_001165958 /// NM_001165959 /// NM_018530 /// XM_005257508 /// XM_005257510 /// XM_005257511 /// XM_006721974 0005737 // cytoplasm // inferred from electronic annotation 219234_x_at NM_024583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024583.1 /DEF=Homo sapiens hypothetical protein FLJ23142 (FLJ23142), mRNA. /FEA=mRNA /GEN=FLJ23142 /PROD=hypothetical protein FLJ23142 /DB_XREF=gi:13375765 /UG=Hs.20999 hypothetical protein FLJ23142 /FL=gb:NM_024583.1 NM_024583 secernin 3 SCRN3 79634 NM_001193528 /// NM_024583 /// XM_005246853 /// XM_005246854 /// XM_005246855 /// XM_005246856 /// XM_005246857 0006508 // proteolysis // inferred from electronic annotation 0016805 // dipeptidase activity // inferred from electronic annotation 219235_s_at NM_023923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023923.1 /DEF=Homo sapiens hypothetical protein FLJ13171 (FLJ13171), mRNA. /FEA=mRNA /GEN=FLJ13171 /PROD=hypothetical protein FLJ13171 /DB_XREF=gi:12965188 /UG=Hs.225641 hypothetical protein FLJ13171 /FL=gb:AF130081.1 gb:NM_023923.1 NM_023923 phosphatase and actin regulator 4 PHACTR4 65979 NM_001048183 /// NM_023923 /// XM_005245970 /// XM_006710842 /// XM_006710843 /// XM_006710844 /// XM_006710845 /// XM_006710846 /// XM_006710847 /// XM_006710848 /// XM_006710849 /// XM_006710850 /// XM_006710851 /// XM_006710852 0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0007266 // Rho protein signal transduction // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity /// 0061386 // closure of optic fissure // inferred from sequence or structural similarity /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0008157 // protein phosphatase 1 binding // inferred from sequence or structural similarity /// 0071862 // protein phosphatase type 1 activator activity // inferred from sequence or structural similarity 219236_at NM_024897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024897.1 /DEF=Homo sapiens hypothetical protein FLJ22672 (FLJ22672), mRNA. /FEA=mRNA /GEN=FLJ22672 /PROD=hypothetical protein FLJ22672 /DB_XREF=gi:13376350 /UG=Hs.235873 hypothetical protein FLJ22672 /FL=gb:NM_024897.1 NM_024897 progestin and adipoQ receptor family member VI PAQR6 79957 NM_001272104 /// NM_001272105 /// NM_001272106 /// NM_001272107 /// NM_001272108 /// NM_001272109 /// NM_001272110 /// NM_001272111 /// NM_001272112 /// NM_001272113 /// NM_024897 /// NM_198406 /// NR_073610 /// XM_005245491 /// XM_005245494 /// XM_006711542 /// XM_006711543 /// XM_006711544 /// XM_006711545 /// XM_006711546 /// XM_006711547 /// XM_006711548 /// XM_006711549 /// XM_006711550 /// XM_006711551 /// XM_006711552 /// XM_006711553 /// XM_006711554 /// XR_426796 /// XR_426797 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded 219237_s_at NM_024920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024920.1 /DEF=Homo sapiens hypothetical protein FLJ14281 (FLJ14281), mRNA. /FEA=mRNA /GEN=FLJ14281 /PROD=hypothetical protein FLJ14281 /DB_XREF=gi:13376391 /UG=Hs.266957 hypothetical protein FLJ14281 /FL=gb:NM_024920.1 NM_024920 DnaJ (Hsp40) homolog, subfamily B, member 14 DNAJB14 79982 NM_001031723 /// NM_001278310 /// NM_001278311 /// NM_024920 /// XM_005263234 /// XM_006714311 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219238_at NM_017837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017837.1 /DEF=Homo sapiens hypothetical protein FLJ20477 (FLJ20477), mRNA. /FEA=mRNA /GEN=FLJ20477 /PROD=hypothetical protein FLJ20477 /DB_XREF=gi:8923441 /UG=Hs.26994 hypothetical protein FLJ20477 /FL=gb:NM_017837.1 NM_017837 phosphatidylinositol glycan anchor biosynthesis, class V PIGV 55650 NM_001202554 /// NM_017837 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from genetic interaction /// 0006506 // GPI anchor biosynthetic process // inferred from mutant phenotype /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from genetic interaction /// 0097502 // mannosylation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000030 // mannosyltransferase activity // inferred from genetic interaction /// 0000030 // mannosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 219239_s_at NM_018293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018293.1 /DEF=Homo sapiens hypothetical protein FLJ10997 (FLJ10997), mRNA. /FEA=mRNA /GEN=FLJ10997 /PROD=hypothetical protein FLJ10997 /DB_XREF=gi:8922809 /UG=Hs.27595 hypothetical protein FLJ10997 /FL=gb:NM_018293.1 NM_018293 zinc finger protein 654 ZNF654 55279 NM_018293 /// NM_032198 /// XM_005264762 /// XM_006713246 /// XM_006713247 /// XM_006713248 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219240_s_at NM_024942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024942.1 /DEF=Homo sapiens hypothetical protein FLJ13490 (FLJ13490), mRNA. /FEA=mRNA /GEN=FLJ13490 /PROD=hypothetical protein FLJ13490 /DB_XREF=gi:13376420 /UG=Hs.282977 hypothetical protein FLJ13490 /FL=gb:NM_024942.1 NM_024942 chromosome 10 open reading frame 88 C10orf88 80007 NM_024942 0042802 // identical protein binding // inferred from electronic annotation 219241_x_at NM_017857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017857.1 /DEF=Homo sapiens hypothetical protein FLJ20515 (FLJ20515), mRNA. /FEA=mRNA /GEN=FLJ20515 /PROD=hypothetical protein FLJ20515 /DB_XREF=gi:8923482 /UG=Hs.29173 hypothetical protein FLJ20515 /FL=gb:NM_017857.1 NM_017857 slingshot protein phosphatase 3 SSH3 54961 NM_017857 /// NM_018276 /// XM_005274070 /// XM_005274071 /// XM_005274072 /// XM_006718592 /// XR_247205 /// XR_247206 0006470 // protein dephosphorylation // not recorded /// 0008064 // regulation of actin polymerization or depolymerization // not recorded /// 0010591 // regulation of lamellipodium assembly // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 219242_at NM_025180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025180.1 /DEF=Homo sapiens hypothetical protein FLJ13386 (FLJ13386), mRNA. /FEA=mRNA /GEN=FLJ13386 /PROD=hypothetical protein FLJ13386 /DB_XREF=gi:13376771 /UG=Hs.300876 hypothetical protein FLJ13386 /FL=gb:NM_025180.1 NM_025180 centrosomal protein 63kDa CEP63 80254 NM_001042383 /// NM_001042384 /// NM_001042400 /// NM_025180 /// XM_005247795 /// XM_005247797 /// XM_005247799 /// XM_006713759 /// XM_006713760 /// XM_006713761 /// XM_006713762 /// XM_006713763 /// XM_006713764 /// XM_006713765 /// XM_006713766 0000077 // DNA damage checkpoint // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0042770 // signal transduction in response to DNA damage // inferred from sequence or structural similarity /// 0051225 // spindle assembly // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219243_at NM_018326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018326.1 /DEF=Homo sapiens hypothetical protein FLJ11110 (FLJ11110), mRNA. /FEA=mRNA /GEN=FLJ11110 /PROD=hypothetical protein FLJ11110 /DB_XREF=gi:8922872 /UG=Hs.30822 hypothetical protein FLJ11110 /FL=gb:NM_018326.1 NM_018326 GTPase, IMAP family member 4 GIMAP4 55303 NM_018326 /// XM_005250017 /// XM_005250018 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219244_s_at NM_022163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022163.1 /DEF=Homo sapiens chromosome 15 open reading frame 4 (C15ORF4), mRNA. /FEA=mRNA /GEN=C15ORF4 /PROD=P2ECSL protein /DB_XREF=gi:11545915 /UG=Hs.332428 P2ECSL protein /FL=gb:AF205435.1 gb:NM_022163.1 NM_022163 mitochondrial ribosomal protein L46 MRPL46 26589 NM_022163 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 219245_s_at AI309636 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI309636 /FEA=EST /DB_XREF=gi:4004507 /DB_XREF=est:qo77g11.x1 /CLONE=IMAGE:1914596 /UG=Hs.33533 hypothetical protein FLJ13491 /FL=gb:NM_024623.1 AI309636 2-oxoglutarate and iron-dependent oxygenase domain containing 2 OGFOD2 79676 NM_024623 0055114 // oxidation-reduction process // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 219246_s_at NM_024623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024623.1 /DEF=Homo sapiens hypothetical protein FLJ13491 (FLJ13491), mRNA. /FEA=mRNA /GEN=FLJ13491 /PROD=hypothetical protein FLJ13491 /DB_XREF=gi:13375845 /UG=Hs.33533 hypothetical protein FLJ13491 /FL=gb:NM_024623.1 NM_024623 2-oxoglutarate and iron-dependent oxygenase domain containing 2 OGFOD2 79676 NM_024623 0055114 // oxidation-reduction process // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 219247_s_at NM_024630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024630.1 /DEF=Homo sapiens hypothetical protein FLJ20984 (FLJ20984), mRNA. /FEA=mRNA /GEN=FLJ20984 /PROD=hypothetical protein FLJ20984 /DB_XREF=gi:13375857 /UG=Hs.38270 hypothetical protein FLJ20984 /FL=gb:NM_024630.1 NM_024630 zinc finger, DHHC-type containing 14 ZDHHC14 79683 NM_024630 /// NM_153746 /// XM_005267146 0008152 // metabolic process // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219248_at NM_025264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025264.1 /DEF=Homo sapiens hypothetical protein MGC2454 (MGC2454), mRNA. /FEA=mRNA /GEN=MGC2454 /PROD=hypothetical protein MGC2454 /DB_XREF=gi:13376879 /UG=Hs.38399 hypothetical protein MGC2454 /FL=gb:BC004163.1 gb:NM_025264.1 NM_025264 THUMP domain containing 2 THUMPD2 80745 NM_025264 /// NR_028102 /// XM_005264577 /// XM_005264579 /// XM_005264580 /// XM_006712106 /// XM_006712107 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219249_s_at NM_021939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021939.1 /DEF=Homo sapiens hypothetical protein FLJ22041 similar to FK506 binding proteins (FLJ22041), mRNA. /FEA=mRNA /GEN=FLJ22041 /PROD=hypothetical protein FLJ22041 similar to FK506binding proteins /DB_XREF=gi:11345475 /UG=Hs.3849 hypothetical protein FLJ22041 similar to FK506 binding proteins /FL=gb:NM_021939.1 gb:AB045981.1 NM_021939 FK506 binding protein 10, 65 kDa FKBP10 60681 NM_021939 /// XM_006722008 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219250_s_at NM_013281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013281.1 /DEF=Homo sapiens fibronectin leucine rich transmembrane protein 3 (FLRT3), mRNA. /FEA=mRNA /GEN=FLRT3 /PROD=fibronectin leucine rich transmembrane protein3 /DB_XREF=gi:7019382 /UG=Hs.41296 fibronectin leucine rich transmembrane protein 3 /FL=gb:AF169677.1 gb:NM_013281.1 NM_013281 fibronectin leucine rich transmembrane protein 3 FLRT3 23767 NM_013281 /// NM_198391 /// XM_005260682 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 219251_s_at NM_018051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018051.1 /DEF=Homo sapiens hypothetical protein FLJ10300 (FLJ10300), mRNA. /FEA=mRNA /GEN=FLJ10300 /PROD=hypothetical protein FLJ10300 /DB_XREF=gi:8922337 /UG=Hs.42233 hypothetical protein FLJ10300 /FL=gb:NM_018051.1 NM_018051 WD repeat domain 60 WDR60 55112 NM_018051 /// XM_005249549 /// XM_005249550 /// XM_006716041 /// XR_242045 /// XR_428179 0030030 // cell projection organization // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219252_s_at NM_017856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017856.1 /DEF=Homo sapiens hypothetical protein FLJ20514 (FLJ20514), mRNA. /FEA=mRNA /GEN=FLJ20514 /PROD=hypothetical protein FLJ20514 /DB_XREF=gi:8923480 /UG=Hs.44423 hypothetical protein FLJ20514 /FL=gb:NM_017856.1 NM_017856 gem (nuclear organelle) associated protein 8 GEMIN8 54960 NM_001042479 /// NM_001042480 /// NM_017856 /// XM_005274555 /// XM_005274556 /// XM_006724501 /// XM_006724502 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219253_at NM_024121 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024121.1 /DEF=Homo sapiens hypothetical protein FLJ20979 (FLJ20979), mRNA. /FEA=mRNA /GEN=FLJ20979 /PROD=hypothetical protein FLJ20979 /DB_XREF=gi:13129145 /UG=Hs.44680 hypothetical protein FLJ20979 /FL=gb:NM_024121.1 NM_024121 transmembrane protein 185B TMEM185B 79134 NM_024121 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219254_at NM_024648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024648.1 /DEF=Homo sapiens hypothetical protein FLJ22222 (FLJ22222), mRNA. /FEA=mRNA /GEN=FLJ22222 /PROD=hypothetical protein FLJ22222 /DB_XREF=gi:13375890 /UG=Hs.54558 hypothetical protein FLJ22222 /FL=gb:NM_024648.1 NM_024648 2-oxoglutarate and iron-dependent oxygenase domain containing 3 OGFOD3 79701 NM_024648 /// NM_175902 /// NR_033265 /// XR_430034 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 219255_x_at NM_018725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018725.1 /DEF=Homo sapiens IL-17B receptor (IL17BR), mRNA. /FEA=mRNA /GEN=IL17BR /PROD=IL-17B receptor /DB_XREF=gi:8923816 /UG=Hs.5470 IL-17B receptor /FL=gb:BC000980.1 gb:AF212365.1 gb:NM_018725.1 gb:AF208110.1 NM_018725 interleukin 17 receptor B IL17RB 55540 NM_018725 /// NM_172234 /// XM_005265310 /// XM_005265311 /// XM_005265312 /// XM_006713253 /// XM_006713254 /// XM_006713255 /// XM_006713256 /// XR_245147 0001558 // regulation of cell growth // non-traceable author statement /// 0006952 // defense response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // non-traceable author statement 219256_s_at NM_018986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018986.1 /DEF=Homo sapiens hypothetical protein (FLJ20356), mRNA. /FEA=mRNA /GEN=FLJ20356 /PROD=hypothetical protein /DB_XREF=gi:9506676 /UG=Hs.61053 hypothetical protein /FL=gb:NM_018986.1 NM_018986 SH3 domain and tetratricopeptide repeats 1 SH3TC1 54436 NM_018986 /// XM_005247974 /// XM_006713888 /// XM_006713889 /// XM_006713890 /// XM_006713891 /// XR_241652 /// XR_427478 0005515 // protein binding // inferred from electronic annotation 219257_s_at NM_021972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021972.1 /DEF=Homo sapiens sphingosine kinase 1 (SPHK1), mRNA. /FEA=mRNA /GEN=SPHK1 /PROD=sphingosine kinase 1 /DB_XREF=gi:11464966 /UG=Hs.68061 sphingosine kinase 1 /FL=gb:NM_021972.1 gb:AF238083.1 gb:AF200328.1 NM_021972 sphingosine kinase 1 SPHK1 8877 NM_001142601 /// NM_001142602 /// NM_021972 /// NM_182965 /// XM_005257766 0001568 // blood vessel development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001956 // positive regulation of neurotransmitter secretion // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006670 // sphingosine metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010803 // regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0019371 // cyclooxygenase pathway // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032651 // regulation of interleukin-1 beta production // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from direct assay /// 0046521 // sphingoid catabolic process // non-traceable author statement /// 0046834 // lipid phosphorylation // inferred from direct assay /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008481 // sphinganine kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017050 // D-erythro-sphingosine kinase activity // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from physical interaction 219258_at NM_017858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017858.1 /DEF=Homo sapiens hypothetical protein FLJ20516 (FLJ20516), mRNA. /FEA=mRNA /GEN=FLJ20516 /PROD=hypothetical protein FLJ20516 /DB_XREF=gi:8923484 /UG=Hs.70811 hypothetical protein FLJ20516 /FL=gb:BC000870.1 gb:NM_017858.1 NM_017858 TIMELESS interacting protein TIPIN 54962 NM_001289986 /// NM_017858 /// XM_005254521 /// XM_005254522 /// XM_005254523 /// XM_006720593 /// XM_006720594 /// XM_006720595 0000076 // DNA replication checkpoint // inferred from mutant phenotype /// 0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009411 // response to UV // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // inferred from mutant phenotype /// 0033262 // regulation of nuclear cell cycle DNA replication // traceable author statement /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0048478 // replication fork protection // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219259_at NM_022367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022367.1 /DEF=Homo sapiens hypothetical protein FLJ12287 similar to semaphorins (FLJ12287), mRNA. /FEA=mRNA /GEN=FLJ12287 /PROD=hypothetical protein FLJ12287 similar tosemaphorins /DB_XREF=gi:11641290 /UG=Hs.7634 hypothetical protein FLJ12287 similar to semaphorins /FL=gb:NM_022367.1 gb:AB029394.1 NM_022367 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A SEMA4A 64218 NM_001193300 /// NM_001193301 /// NM_001193302 /// NM_022367 0001525 // angiogenesis // inferred from electronic annotation /// 0002292 // T cell differentiation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010594 // regulation of endothelial cell migration // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045063 // T-helper 1 cell differentiation // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219260_s_at NM_015362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015362.1 /DEF=Homo sapiens HSPC002 protein (HSPC002), mRNA. /FEA=mRNA /GEN=HSPC002 /PROD=HSPC002 protein /DB_XREF=gi:7661725 /UG=Hs.76907 HSPC002 protein /FL=gb:AF070658.1 gb:NM_015362.1 NM_015362 elongator acetyltransferase complex subunit 5 ELP5 23587 NM_015362 /// NM_203413 /// NM_203414 /// NM_203415 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219261_at NM_024067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024067.1 /DEF=Homo sapiens hypothetical protein MGC2718 (MGC2718), mRNA. /FEA=mRNA /GEN=MGC2718 /PROD=hypothetical protein MGC2718 /DB_XREF=gi:13129045 /UG=Hs.81057 hypothetical protein MGC2718 /FL=gb:BC001076.1 gb:NM_024067.1 gb:BC005121.1 NM_024067 chromosome 7 open reading frame 26 C7orf26 79034 NM_024067 /// XM_005249845 /// XR_242101 219262_at NM_024670 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024670.1 /DEF=Homo sapiens hypothetical protein FLJ23414 (FLJ23414), mRNA. /FEA=mRNA /GEN=FLJ23414 /PROD=hypothetical protein FLJ23414 /DB_XREF=gi:13375929 /UG=Hs.85567 hypothetical protein FLJ23414 /FL=gb:NM_024670.1 NM_024670 suppressor of variegation 3-9 homolog 2 (Drosophila) SUV39H2 79723 NM_001193424 /// NM_001193425 /// NM_001193426 /// NM_001193427 /// NM_024670 /// NR_034181 /// XM_006717503 0006333 // chromatin assembly or disassembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0036123 // histone H3-K9 dimethylation // inferred from sequence or structural similarity /// 0036124 // histone H3-K9 trimethylation // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from direct assay 219263_at NM_024539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024539.1 /DEF=Homo sapiens hypothetical protein FLJ23516 (FLJ23516), mRNA. /FEA=mRNA /GEN=FLJ23516 /PROD=hypothetical protein FLJ23516 /DB_XREF=gi:13375696 /UG=Hs.9238 hypothetical protein FLJ23516 /FL=gb:NM_024539.1 NM_024539 ring finger protein 128, E3 ubiquitin protein ligase RNF128 79589 NM_024539 /// NM_194463 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219264_s_at NM_013239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013239.1 /DEF=Homo sapiens protein phosphatase 2A 48 kDa regulatory subunit (PR48), mRNA. /FEA=mRNA /GEN=PR48 /PROD=protein phosphatase 2A 48 kDa regulatorysubunit /DB_XREF=gi:7019500 /UG=Hs.124942 protein phosphatase 2A 48 kDa regulatory subunit /FL=gb:AF135016.1 gb:NM_013239.1 NM_013239 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like /// protein phosphatase 2, regulatory subunit B'', beta LOC102725016 /// PPP2R3B 28227 /// 102725016 NM_013239 /// NM_199326 /// XM_005274427 /// XM_005274428 /// XM_005274776 /// XM_005274777 /// XM_006710253 /// XM_006724442 /// XM_006724863 /// XM_006725649 /// XM_006725650 /// XM_006725651 /// XM_006725652 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004722 // protein serine/threonine phosphatase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219265_at NM_024761 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024761.1 /DEF=Homo sapiens hypothetical protein FLJ13204 (FLJ13204), mRNA. /FEA=mRNA /GEN=FLJ13204 /PROD=hypothetical protein FLJ13204 /DB_XREF=gi:13376100 /UG=Hs.128905 hypothetical protein FLJ13204 /FL=gb:NM_024761.1 NM_024761 MOB kinase activator 3B MOB3B 79817 NM_024761 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219266_at NM_021632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021632.1 /DEF=Homo sapiens zinc-finger protein ZBRK1 (ZBRK1), mRNA. /FEA=mRNA /GEN=ZBRK1 /PROD=zinc-finger protein ZBRK1 /DB_XREF=gi:11056003 /UG=Hs.130965 zinc-finger protein ZBRK1 /FL=gb:AF295096.1 gb:AF309561.1 gb:NM_021632.1 NM_021632 zinc finger protein 350 ZNF350 59348 NM_021632 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219267_at NM_016433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016433.1 /DEF=Homo sapiens glycolipid transfer protein (LOC51228), mRNA. /FEA=mRNA /GEN=LOC51228 /PROD=glycolipid transfer protein /DB_XREF=gi:7705986 /UG=Hs.135723 glycolipid transfer protein /FL=gb:AF209704.1 gb:NM_016433.1 NM_016433 glycolipid transfer protein GLTP 51228 NM_016433 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0046836 // glycolipid transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008289 // lipid binding // inferred from direct assay /// 0017089 // glycolipid transporter activity // inferred from direct assay /// 0051861 // glycolipid binding // inferred from direct assay 219268_at NM_018208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018208.1 /DEF=Homo sapiens hypothetical protein FLJ10761 (FLJ10761), mRNA. /FEA=mRNA /GEN=FLJ10761 /PROD=hypothetical protein FLJ10761 /DB_XREF=gi:8922649 /UG=Hs.13684 hypothetical protein FLJ10761 /FL=gb:NM_018208.1 NM_018208 ethanolamine kinase 2 ETNK2 55224 NM_018208 /// XM_005245302 /// XM_005245303 /// XM_005245304 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219269_at NM_024567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024567.1 /DEF=Homo sapiens hypothetical protein FLJ21616 (FLJ21616), mRNA. /FEA=mRNA /GEN=FLJ21616 /PROD=hypothetical protein FLJ21616 /DB_XREF=gi:13375737 /UG=Hs.14562 hypothetical protein FLJ21616 /FL=gb:NM_024567.1 NM_024567 homeobox containing 1 HMBOX1 79618 NM_001135726 /// NM_024567 /// XM_005273635 /// XM_005273636 /// XM_005273637 /// XM_005273638 /// XM_005273639 /// XM_005273640 /// XM_005273641 /// XM_006716396 /// XM_006716397 /// XM_006716398 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 219270_at NM_024111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024111.1 /DEF=Homo sapiens hypothetical protein MGC4504 (MGC4504), mRNA. /FEA=mRNA /GEN=MGC4504 /PROD=hypothetical protein MGC4504 /DB_XREF=gi:13129125 /UG=Hs.155569 hypothetical protein MGC4504 /FL=gb:BC001847.1 gb:NM_024111.1 NM_024111 ChaC, cation transport regulator homolog 1 (E. coli) CHAC1 79094 NM_001142776 /// NM_024111 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010955 // negative regulation of protein processing // inferred from mutant phenotype /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0045746 // negative regulation of Notch signaling pathway // inferred from mutant phenotype /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay 0005112 // Notch binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 219271_at NM_024572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024572.1 /DEF=Homo sapiens hypothetical protein FLJ12691 (FLJ12691), mRNA. /FEA=mRNA /GEN=FLJ12691 /PROD=hypothetical protein FLJ12691 /DB_XREF=gi:13375743 /UG=Hs.15830 hypothetical protein FLJ12691 /FL=gb:NM_024572.1 NM_024572 polypeptide N-acetylgalactosaminyltransferase 14 GALNT14 79623 NM_001253826 /// NM_001253827 /// NM_024572 /// NR_045602 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219272_at NM_018207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018207.1 /DEF=Homo sapiens hypothetical protein FLJ10759 (FLJ10759), mRNA. /FEA=mRNA /GEN=FLJ10759 /PROD=hypothetical protein FLJ10759 /DB_XREF=gi:8922647 /UG=Hs.15921 hypothetical protein FLJ10759 /FL=gb:BC001222.1 gb:NM_018207.1 NM_018207 tripartite motif containing 62 TRIM62 55223 NM_018207 /// XM_006710736 /// XM_006710737 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0046596 // regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219273_at NM_003858 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003858.1 /DEF=Homo sapiens cyclin K (CCNK), mRNA. /FEA=mRNA /GEN=CCNK /PROD=cyclin K /DB_XREF=gi:4502624 /UG=Hs.164866 cyclin K /FL=gb:AF060515.1 gb:NM_003858.1 NM_003858 cyclin K CCNK 8812 NM_001099402 /// NM_003858 /// XM_005268154 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from genetic interaction 0002944 // cyclin K-CDK12 complex // inferred from physical interaction /// 0002945 // cyclin K-CDK13 complex // inferred from physical interaction /// 0005634 // nucleus // inferred from electronic annotation 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction 219274_at NM_012338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012338.1 /DEF=Homo sapiens transmembrane 4 superfamily member (tetraspan NET-2) (NET-2), mRNA. /FEA=mRNA /GEN=NET-2 /PROD=transmembrane 4 superfamily member (tetraspanNET-2) /DB_XREF=gi:6912527 /UG=Hs.16529 transmembrane 4 superfamily member (tetraspan NET-2) /FL=gb:AF124522.1 gb:NM_012338.1 NM_012338 tetraspanin 12 TSPAN12 23554 NM_012338 /// XM_005250239 0001525 // angiogenesis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement 0042813 // Wnt-activated receptor activity // inferred from sequence or structural similarity 219275_at NM_004708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004708.1 /DEF=Homo sapiens programmed cell death 5 (PDCD5), mRNA. /FEA=mRNA /GEN=PDCD5 /PROD=programmed cell death 5 /DB_XREF=gi:4759223 /UG=Hs.166468 programmed cell death 5 /FL=gb:AF014955.1 gb:NM_004708.1 NM_004708 programmed cell death 5 PDCD5 9141 NM_004708 /// XM_005259392 0006915 // apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 219276_x_at NM_024828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024828.1 /DEF=Homo sapiens hypothetical protein FLJ13657 (FLJ13657), mRNA. /FEA=mRNA /GEN=FLJ13657 /PROD=hypothetical protein FLJ13657 /DB_XREF=gi:13376229 /UG=Hs.178357 hypothetical protein FLJ13657 /FL=gb:NM_024828.1 NM_024828 caspase activity and apoptosis inhibitor 1 CAAP1 79886 NM_001167575 /// NM_024828 /// XM_005251581 0006915 // apoptotic process // inferred from electronic annotation 219277_s_at NM_018245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018245.1 /DEF=Homo sapiens hypothetical protein FLJ10851 (FLJ10851), mRNA. /FEA=mRNA /GEN=FLJ10851 /PROD=hypothetical protein FLJ10851 /DB_XREF=gi:8922715 /UG=Hs.17860 hypothetical protein FLJ10851 /FL=gb:NM_018245.1 NM_018245 oxoglutarate dehydrogenase-like OGDHL 55753 NM_001143996 /// NM_001143997 /// NM_018245 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219278_at NM_004672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004672.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 6 (MAP3K6), mRNA. /FEA=mRNA /GEN=MAP3K6 /PROD=mitogen-activated protein kinase kinase kinase6 /DB_XREF=gi:4758701 /UG=Hs.194694 mitogen-activated protein kinase kinase kinase 6 /FL=gb:AF100318.1 gb:NM_004672.1 NM_004672 mitogen-activated protein kinase kinase kinase 6 MAP3K6 9064 NM_004672 /// XM_005246029 /// XR_241205 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219279_at NM_017718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017718.1 /DEF=Homo sapiens hypothetical protein FLJ20220 (FLJ20220), mRNA. /FEA=mRNA /GEN=FLJ20220 /PROD=hypothetical protein FLJ20220 /DB_XREF=gi:8923209 /UG=Hs.21126 hypothetical protein FLJ20220 /FL=gb:NM_017718.1 NM_017718 dedicator of cytokinesis 10 DOCK10 55619 NM_001290263 /// NM_014689 /// NM_017718 /// XM_005246672 /// XM_005246673 /// XM_005246674 /// XM_006712616 /// XM_006712617 /// XM_006712618 /// XM_006712619 /// XM_006712620 /// XM_006712621 /// XM_006712622 /// XM_006712623 /// XM_006712624 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 219280_at NM_018963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018963.1 /DEF=Homo sapiens WD repeat domain 9 (WDR9), mRNA. /FEA=mRNA /GEN=WDR9 /PROD=WD repeat domain 9 /DB_XREF=gi:11321643 /UG=Hs.225674 WD repeat domain 9 /FL=gb:NM_018963.1 NM_018963 bromodomain and WD repeat domain containing 1 BRWD1 54014 NM_001007246 /// NM_018963 /// NM_033656 /// XM_005260994 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219281_at NM_012331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012331.2 /DEF=Homo sapiens methionine sulfoxide reductase A (MSRA), mRNA. /FEA=mRNA /GEN=MSRA /PROD=methionine sulfoxide reductase A /DB_XREF=gi:13259538 /UG=Hs.26458 methionine sulfoxide reductase A /FL=gb:NM_012331.2 gb:AF183420.1 NM_012331 methionine sulfoxide reductase A MSRA 4482 NM_001135670 /// NM_001135671 /// NM_001199729 /// NM_012331 0006464 // cellular protein modification process // traceable author statement /// 0006555 // methionine metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030091 // protein repair // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008113 // peptide-methionine (S)-S-oxide reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation 219282_s_at NM_015930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015930.1 /DEF=Homo sapiens vanilloid receptor-like protein 1 (VRL-1), mRNA. /FEA=mRNA /GEN=VRL-1 /PROD=vanilloid receptor-like protein 1 /DB_XREF=gi:7706764 /UG=Hs.279746 vanilloid receptor-like protein 1 /FL=gb:AF129112.1 gb:NM_015930.1 NM_015930 transient receptor potential cation channel, subfamily V, member 2 TRPV2 51393 NM_016113 /// XM_005256676 /// XM_005256677 /// XM_005256678 /// XM_006721541 /// XM_006721542 /// XM_006721543 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007600 // sensory perception // traceable author statement /// 0009266 // response to temperature stimulus // inferred from direct assay /// 0009408 // response to heat // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation 0005216 // ion channel activity // traceable author statement /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // traceable author statement 219283_at NM_014158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014158.1 /DEF=Homo sapiens HSPC067 protein (HSPC067), mRNA. /FEA=mRNA /GEN=HSPC067 /PROD=HSPC067 protein /DB_XREF=gi:7661771 /UG=Hs.279938 HSPC067 protein /FL=gb:AF161552.1 gb:NM_014158.1 NM_014158 C1GALT1-specific chaperone 1 C1GALT1C1 29071 NM_001011551 /// NM_152692 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219284_at NM_024610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024610.1 /DEF=Homo sapiens hypothetical protein FLJ22623 (FLJ22623), mRNA. /FEA=mRNA /GEN=FLJ22623 /PROD=hypothetical protein FLJ22623 /DB_XREF=gi:13375820 /UG=Hs.29169 hypothetical protein FLJ22623 /FL=gb:NM_024610.1 NM_024610 HSPB (heat shock 27kDa) associated protein 1 HSPBAP1 79663 NM_024610 /// XM_005247761 /// XM_005247762 0006950 // response to stress // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219285_s_at NM_016350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016350.1 /DEF=Homo sapiens ninein (LOC51199), mRNA. /FEA=mRNA /GEN=LOC51199 /PROD=ninein /DB_XREF=gi:7705946 /UG=Hs.44054 ninein (GSK3B interacting protein) /FL=gb:AF212162.1 gb:NM_016350.1 NM_016350 ninein (GSK3B interacting protein) NIN 51199 NM_016350 /// NM_020921 /// NM_182944 /// NM_182945 /// NM_182946 /// XM_005267735 /// XM_005267736 /// XM_005267737 /// XM_006720160 /// XM_006720161 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0051642 // centrosome localization // traceable author statement /// 0090222 // centrosome-templated microtubule nucleation // inferred from electronic annotation 0000922 // spindle pole // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 219286_s_at NM_022768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022768.1 /DEF=Homo sapiens hypothetical protein FLJ12479 (FLJ12479), mRNA. /FEA=mRNA /GEN=FLJ12479 /PROD=hypothetical protein FLJ12479 /DB_XREF=gi:12232444 /UG=Hs.46670 hypothetical protein FLJ12479 /FL=gb:NM_022768.1 NM_022768 RNA binding motif protein 15 RBM15 64783 NM_001201545 /// NM_022768 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0007221 // positive regulation of transcription of Notch receptor target // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048536 // spleen development // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219287_at NM_014505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014505.1 /DEF=Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 4 (KCNMB4), mRNA. /FEA=mRNA /GEN=KCNMB4 /PROD=potassium large conductance calcium-activatedchannel, subfamily M, beta member 4 /DB_XREF=gi:7657254 /UG=Hs.46784 potassium large conductance calcium-activated channel, subfamily M, beta member 4 /FL=gb:AF207992.1 gb:NM_014505.1 gb:AF160967.1 gb:AF215891.1 gb:AF170917.1 NM_014505 potassium large conductance calcium-activated channel, subfamily M, beta member 4 KCNMB4 27345 NM_014505 /// XR_245917 0001508 // action potential // inferred from direct assay /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019228 // neuronal action potential // inferred from direct assay /// 0019229 // regulation of vasoconstriction // traceable author statement /// 0046928 // regulation of neurotransmitter secretion // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay 219288_at NM_020685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020685.1 /DEF=Homo sapiens HT021 (HT021), mRNA. /FEA=mRNA /GEN=HT021 /PROD=HT021 /DB_XREF=gi:10190735 /UG=Hs.47166 HT021 /FL=gb:NM_020685.1 gb:AF236158.1 NM_020685 chromosome 3 open reading frame 14 C3orf14 57415 NM_001291941 /// NM_001291942 /// NM_001291943 /// NM_020685 /// XM_005265338 /// XM_005265339 /// XM_005265340 219289_at NM_017939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017939.1 /DEF=Homo sapiens hypothetical protein FLJ20718 (FLJ20718), mRNA. /FEA=mRNA /GEN=FLJ20718 /PROD=hypothetical protein FLJ20718 /DB_XREF=gi:8923644 /UG=Hs.50579 hypothetical protein FLJ20718 /FL=gb:NM_017939.1 NM_017939 HEAT repeat containing 3 HEATR3 55027 NM_017939 /// NM_182922 /// XM_005256013 /// XM_005256014 0005488 // binding // inferred from electronic annotation 219290_x_at NM_014395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014395.1 /DEF=Homo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1), mRNA. /FEA=mRNA /GEN=DAPP1 /PROD=dual adaptor of phosphotyrosine and3-phosphoinositides /DB_XREF=gi:7657006 /UG=Hs.62643 dual adaptor of phosphotyrosine and 3-phosphoinositides /FL=gb:AF186022.1 gb:NM_014395.1 NM_014395 dual adaptor of phosphotyrosine and 3-phosphoinositides DAPP1 27071 NM_014395 0006470 // protein dephosphorylation // non-traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // non-traceable author statement /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay 219291_at NM_020234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020234.1 /DEF=Homo sapiens x 009 protein (MDS009), mRNA. /FEA=mRNA /GEN=MDS009 /PROD=x 009 protein /DB_XREF=gi:9910425 /UG=Hs.64641 x 009 protein /FL=gb:AF168717.1 gb:NM_020234.1 NM_020234 DTW domain containing 1 DTWD1 56986 NM_001144955 /// NM_020234 /// XM_005254561 /// XM_005254562 219292_at NM_018105 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018105.1 /DEF=Homo sapiens hypothetical protein FLJ10477 (FLJ10477), mRNA. /FEA=mRNA /GEN=FLJ10477 /PROD=hypothetical protein FLJ10477 /DB_XREF=gi:8922445 /UG=Hs.7432 hypothetical protein FLJ10477 /FL=gb:NM_018105.1 NM_018105 THAP domain containing, apoptosis associated protein 1 THAP1 55145 NM_018105 /// NM_199003 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 219293_s_at NM_013341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013341.1 /DEF=Homo sapiens hypothetical protein (PTD004), mRNA. /FEA=mRNA /GEN=PTD004 /PROD=hypothetical protein /DB_XREF=gi:9558756 /UG=Hs.86347 hypothetical protein /FL=gb:AF078859.1 gb:AF078868.1 gb:AF116703.1 gb:NM_013341.1 NM_013341 Obg-like ATPase 1 OLA1 29789 NM_001011708 /// NM_013341 0006200 // ATP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation /// 0043023 // ribosomal large subunit binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219294_at NM_018132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018132.1 /DEF=Homo sapiens hypothetical protein FLJ10545 (FLJ10545), mRNA. /FEA=mRNA /GEN=FLJ10545 /PROD=hypothetical protein FLJ10545 /DB_XREF=gi:8922503 /UG=Hs.88663 hypothetical protein FLJ10545 /FL=gb:NM_018132.1 NM_018132 centromere protein Q CENPQ 55166 NM_018132 /// XM_005249205 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 219295_s_at NM_013363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013363.1 /DEF=Homo sapiens procollagen C-endopeptidase enhancer 2 (PCOLCE2), mRNA. /FEA=mRNA /GEN=PCOLCE2 /PROD=procollagen C-endopeptidase enhancer 2 /DB_XREF=gi:7019482 /UG=Hs.8944 procollagen C-endopeptidase enhancer 2 /FL=gb:AF098269.1 gb:NM_013363.1 NM_013363 procollagen C-endopeptidase enhancer 2 PCOLCE2 26577 NM_013363 0010952 // positive regulation of peptidase activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016504 // peptidase activator activity // inferred from direct assay 219296_at NM_019028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019028.1 /DEF=Homo sapiens hypothetical protein similar to ankyrin repeat-containing priotein AKR1 (FLJ10852), mRNA. /FEA=mRNA /GEN=FLJ10852 /PROD=hypothetical protein similar to ankyrinrepeat-containing priotein AKR1 /DB_XREF=gi:9506622 /UG=Hs.95744 hypothetical protein similar to ankyrin repeat-containing priotein AKR1 /FL=gb:NM_019028.1 NM_019028 zinc finger, DHHC-type containing 13 ZDHHC13 54503 NM_001001483 /// NM_019028 /// XM_005252996 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015095 // magnesium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0016409 // palmitoyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219297_at NM_019045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019045.1 /DEF=Homo sapiens similar to rab11-binding protein (FLJ11116), mRNA. /FEA=mRNA /GEN=FLJ11116 /PROD=similar to rab11-binding protein /DB_XREF=gi:9506636 /UG=Hs.98510 similar to rab11-binding protein /FL=gb:NM_019045.1 NM_019045 WD repeat domain 44 WDR44 54521 NM_001184965 /// NM_001184966 /// NM_019045 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219298_at NM_024693 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024693.1 /DEF=Homo sapiens hypothetical protein FLJ20909 (FLJ20909), mRNA. /FEA=mRNA /GEN=FLJ20909 /PROD=hypothetical protein FLJ20909 /DB_XREF=gi:13375972 /UG=Hs.98855 hypothetical protein FLJ20909 /FL=gb:NM_024693.1 NM_024693 enoyl CoA hydratase domain containing 3 ECHDC3 79746 NM_024693 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation 219299_at NM_017956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017956.1 /DEF=Homo sapiens hypothetical protein FLJ20772 (FLJ20772), mRNA. /FEA=mRNA /GEN=FLJ20772 /PROD=hypothetical protein FLJ20772 /DB_XREF=gi:8923675 /UG=Hs.9925 hypothetical protein FLJ20772 /FL=gb:NM_017956.1 NM_017956 tRNA methyltransferase 12 homolog (S. cerevisiae) TRMT12 55039 NM_017956 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219300_s_at AB020675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB020675.1 /DEF=Homo sapiens mRNA for KIAA0868 protein, partial cds. /FEA=mRNA /GEN=KIAA0868 /PROD=KIAA0868 protein /DB_XREF=gi:4240224 /UG=Hs.106552 cell recognition molecule Caspr2 /FL=gb:AF193613.1 gb:NM_014141.1 AB020675 contactin associated protein-like 2 CNTNAP2 26047 NM_014141 /// XM_006715919 0007155 // cell adhesion // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007610 // behavior // inferred from mutant phenotype /// 0007612 // learning // inferred from mutant phenotype /// 0008038 // neuron recognition // non-traceable author statement /// 0019226 // transmission of nerve impulse // non-traceable author statement /// 0021756 // striatum development // inferred from expression pattern /// 0021761 // limbic system development // inferred from expression pattern /// 0021794 // thalamus development // inferred from expression pattern /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030534 // adult behavior // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from mutant phenotype /// 0045163 // clustering of voltage-gated potassium channels // inferred from sequence or structural similarity /// 0071109 // superior temporal gyrus development // inferred from expression pattern /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030673 // axolemma // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 219301_s_at AU144598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU144598 /FEA=EST /DB_XREF=gi:11006119 /DB_XREF=est:AU144598 /CLONE=HEMBA1002460 /UG=Hs.106552 cell recognition molecule Caspr2 /FL=gb:AF193613.1 gb:NM_014141.1 AU144598 contactin associated protein-like 2 CNTNAP2 26047 NM_014141 /// XM_006715919 0007155 // cell adhesion // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007610 // behavior // inferred from mutant phenotype /// 0007612 // learning // inferred from mutant phenotype /// 0008038 // neuron recognition // non-traceable author statement /// 0019226 // transmission of nerve impulse // non-traceable author statement /// 0021756 // striatum development // inferred from expression pattern /// 0021761 // limbic system development // inferred from expression pattern /// 0021794 // thalamus development // inferred from expression pattern /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030534 // adult behavior // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from mutant phenotype /// 0045163 // clustering of voltage-gated potassium channels // inferred from sequence or structural similarity /// 0071109 // superior temporal gyrus development // inferred from expression pattern /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030673 // axolemma // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 219302_s_at NM_014141 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014141.1 /DEF=Homo sapiens cell recognition molecule Caspr2 (KIAA0868), mRNA. /FEA=mRNA /GEN=KIAA0868 /PROD=cell recognition molecule Caspr2 /DB_XREF=gi:7662349 /UG=Hs.106552 cell recognition molecule Caspr2 /FL=gb:AF193613.1 gb:NM_014141.1 NM_014141 contactin associated protein-like 2 CNTNAP2 26047 NM_014141 /// XM_006715919 0007155 // cell adhesion // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007610 // behavior // inferred from mutant phenotype /// 0007612 // learning // inferred from mutant phenotype /// 0008038 // neuron recognition // non-traceable author statement /// 0019226 // transmission of nerve impulse // non-traceable author statement /// 0021756 // striatum development // inferred from expression pattern /// 0021761 // limbic system development // inferred from expression pattern /// 0021794 // thalamus development // inferred from expression pattern /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030534 // adult behavior // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from mutant phenotype /// 0045163 // clustering of voltage-gated potassium channels // inferred from sequence or structural similarity /// 0071109 // superior temporal gyrus development // inferred from expression pattern /// 0071205 // protein localization to juxtaparanode region of axon // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030673 // axolemma // inferred from direct assay /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 219303_at NM_024546 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024546.1 /DEF=Homo sapiens hypothetical protein FLJ13449 (FLJ13449), mRNA. /FEA=mRNA /GEN=FLJ13449 /PROD=hypothetical protein FLJ13449 /DB_XREF=gi:13375708 /UG=Hs.10711 hypothetical protein FLJ13449 /FL=gb:AL136651.1 gb:NM_024546.1 NM_024546 ring finger protein 219 RNF219 79596 NM_024546 /// XM_006719865 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219304_s_at NM_025208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025208.1 /DEF=Homo sapiens spinal cord-derived growth factor-B (SCDGF-B), mRNA. /FEA=mRNA /GEN=SCDGF-B /PROD=spinal cord-derived growth factor-B /DB_XREF=gi:13376807 /UG=Hs.112885 spinal cord-derived growth factor-B /FL=gb:AB033832.1 gb:AF113216.1 gb:NM_025208.1 gb:AY027517.1 NM_025208 platelet derived growth factor D PDGFD 80310 NM_025208 /// NM_033135 0007275 // multicellular organismal development // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 219305_x_at NM_012168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012168.1 /DEF=Homo sapiens F-box only protein 2 (FBXO2), mRNA. /FEA=mRNA /GEN=FBXO2 /PROD=F-box only protein 2 /DB_XREF=gi:6912363 /UG=Hs.132753 F-box only protein 2 /FL=gb:NM_012168.1 NM_012168 F-box protein 2 FBXO2 26232 NM_012168 /// XR_244788 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from sequence or structural similarity /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219306_at NM_020242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020242.1 /DEF=Homo sapiens kinesin-like protein 2 (hklp2), mRNA. /FEA=mRNA /GEN=hklp2 /PROD=kinesin-like protein 2 /DB_XREF=gi:9910265 /UG=Hs.150587 kinesin-like protein 2 /FL=gb:AB035898.1 gb:NM_020242.1 NM_020242 kinesin family member 15 KIF15 56992 NM_020242 /// XM_005265328 /// XM_006713261 /// XM_006713262 /// XM_006713263 /// XM_006713264 /// XM_006713265 0007018 // microtubule-based movement // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005873 // plus-end kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 219307_at NM_020381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020381.1 /DEF=Homo sapiens candidate tumor suppressor protein (LOC57107), mRNA. /FEA=mRNA /GEN=LOC57107 /PROD=candidate tumor suppressor protein /DB_XREF=gi:9966852 /UG=Hs.16608 candidate tumor suppressor protein /FL=gb:AF254956.1 gb:NM_020381.1 NM_020381 prenyl (decaprenyl) diphosphate synthase, subunit 2 PDSS2 57107 NM_020381 0006744 // ubiquinone biosynthetic process // inferred from direct assay /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000010 // trans-hexaprenyltranstransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0050347 // trans-octaprenyltranstransferase activity // inferred from electronic annotation 219308_s_at NM_012093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012093.1 /DEF=Homo sapiens adenylate kinase 5 (AK5), mRNA. /FEA=mRNA /GEN=AK5 /PROD=adenylate kinase 5 /DB_XREF=gi:6912231 /UG=Hs.18268 adenylate kinase 5 /FL=gb:AF062595.1 gb:NM_012093.1 NM_012093 adenylate kinase 5 AK5 26289 NM_012093 /// NM_174858 /// XM_005270739 /// XM_006710572 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // traceable author statement /// 0006173 // dADP biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0009220 // pyrimidine ribonucleotide biosynthetic process // traceable author statement /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded 219309_at NM_024588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024588.1 /DEF=Homo sapiens hypothetical protein FLJ23584 (FLJ23584), mRNA. /FEA=mRNA /GEN=FLJ23584 /PROD=hypothetical protein FLJ23584 /DB_XREF=gi:13375776 /UG=Hs.22195 hypothetical protein FLJ23584 /FL=gb:NM_024588.1 NM_024588 chromosome 22 open reading frame 46 C22orf46 79640 NM_001142964 /// NM_024588 0005576 // extracellular region // inferred from electronic annotation 219310_at NM_024893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024893.1 /DEF=Homo sapiens hypothetical protein FLJ14220 (FLJ14220), mRNA. /FEA=mRNA /GEN=FLJ14220 /PROD=hypothetical protein FLJ14220 /DB_XREF=gi:13376346 /UG=Hs.233634 hypothetical protein FLJ14220 /FL=gb:NM_024893.1 NM_024893 synapse differentiation inducing 1 SYNDIG1 79953 NM_024893 /// XM_006723626 /// XM_006723627 /// XM_006723628 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from direct assay /// 0097091 // synaptic vesicle clustering // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from sequence or structural similarity 0035254 // glutamate receptor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 219311_at NM_024899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024899.1 /DEF=Homo sapiens hypothetical protein FLJ12542 (FLJ12542), mRNA. /FEA=mRNA /GEN=FLJ12542 /PROD=hypothetical protein FLJ12542 /DB_XREF=gi:13376354 /UG=Hs.236940 hypothetical protein FLJ12542 /FL=gb:NM_024899.1 NM_024899 centrosomal protein 76kDa CEP76 79959 NM_001271989 /// NM_024899 /// NR_073537 /// XM_005258149 /// XM_005258150 /// XM_006722356 /// XM_006722357 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0046599 // regulation of centriole replication // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219312_s_at NM_023929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023929.1 /DEF=Homo sapiens hypothetical protein FLJ12752 (FLJ12752), mRNA. /FEA=mRNA /GEN=FLJ12752 /PROD=hypothetical protein FLJ12752 /DB_XREF=gi:12965200 /UG=Hs.237146 hypothetical protein FLJ12752 /FL=gb:NM_023929.1 NM_023929 zinc finger and BTB domain containing 10 ZBTB10 65986 NM_001105539 /// NM_001277145 /// NM_023929 /// XM_005251287 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219313_at NM_017577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017577.1 /DEF=Homo sapiens hypothetical protein DKFZp434C0328 (DKFZp434C0328), mRNA. /FEA=mRNA /GEN=DKFZp434C0328 /PROD=hypothetical protein DKFZp434C0328 /DB_XREF=gi:8922125 /UG=Hs.24583 hypothetical protein DKFZp434C0328 /FL=gb:NM_017577.1 NM_017577 GRAM domain containing 1C GRAMD1C 54762 NM_001172105 /// NM_017577 /// XM_005247546 /// XM_005247547 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219314_s_at NM_016423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016423.1 /DEF=Homo sapiens zinc finger protein 219 (ZNF219), mRNA. /FEA=mRNA /GEN=ZNF219 /PROD=zinc finger protein 219 /DB_XREF=gi:7705974 /UG=Hs.250493 zinc finger protein 219 /FL=gb:BC000694.1 gb:AB015427.1 gb:NM_016423.1 NM_016423 zinc finger protein 219 ZNF219 51222 NM_001101672 /// NM_001102454 /// NM_016423 /// XM_005267739 /// XM_006720162 /// XM_006720163 /// XM_006720164 0001505 // regulation of neurotransmitter levels // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004969 // histamine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219315_s_at NM_024600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024600.1 /DEF=Homo sapiens hypothetical protein FLJ20898 (FLJ20898), mRNA. /FEA=mRNA /GEN=FLJ20898 /PROD=hypothetical protein FLJ20898 /DB_XREF=gi:13375800 /UG=Hs.25549 hypothetical protein FLJ20898 /FL=gb:NM_024600.1 NM_024600 transmembrane protein 204 TMEM204 79652 NM_001256541 /// NM_024600 0001945 // lymph vessel development // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219316_s_at NM_017791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017791.1 /DEF=Homo sapiens hypothetical protein FLJ20371 (FLJ20371), mRNA. /FEA=mRNA /GEN=FLJ20371 /PROD=hypothetical protein FLJ20371 /DB_XREF=gi:8923349 /UG=Hs.267566 hypothetical protein FLJ20371 /FL=gb:NM_017791.1 NM_017791 feline leukemia virus subgroup C cellular receptor family, member 2 FLVCR2 55640 NM_001195283 /// NM_017791 0006810 // transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015232 // heme transporter activity // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay 219317_at NM_007195 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007195.1 /DEF=Homo sapiens polymerase (DNA directed) iota (POLI), mRNA. /FEA=mRNA /GEN=POLI /PROD=polymerase (DNA directed) iota /DB_XREF=gi:6005847 /UG=Hs.271699 polymerase (DNA directed) iota /FL=gb:AL136670.1 gb:AF140501.1 gb:NM_007195.1 gb:AF245438.1 NM_007195 polymerase (DNA directed) iota POLI 11201 NM_007195 /// XM_005258188 /// XM_005258191 /// XM_005258192 /// XM_006722376 /// XM_006722377 /// XM_006722378 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219318_x_at NM_016060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016060.1 /DEF=Homo sapiens CGI-125 protein (LOC51003), mRNA. /FEA=mRNA /GEN=LOC51003 /PROD=CGI-125 protein /DB_XREF=gi:7705591 /UG=Hs.27289 CGI-125 protein /FL=gb:AF151883.1 gb:NM_016060.1 NM_016060 mediator complex subunit 31 MED31 51003 NM_016060 /// XM_005256671 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 219319_at NM_022462 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022462.1 /DEF=Homo sapiens hypothetical protein FLJ14033 similar to hypoxia inducible factor 3, alpha subunit (FLJ14033), mRNA. /FEA=mRNA /GEN=FLJ14033 /PROD=hypothetical protein FLJ14033 similar to hypoxiainducible factor 3, alpha subunit /DB_XREF=gi:11968004 /UG=Hs.284256 hypothetical protein FLJ14033 similar to hypoxia inducible factor 3, alpha subunit /FL=gb:NM_022462.1 NM_022462 hypoxia inducible factor 3, alpha subunit HIF3A 64344 NM_022462 /// NM_152794 /// NM_152795 /// NM_152796 /// XM_005259152 /// XM_005259153 /// XM_005259154 /// XM_005259155 /// XM_005259156 /// XM_006723324 /// XM_006723325 /// XR_243952 0001666 // response to hypoxia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 219320_at NM_025109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025109.1 /DEF=Homo sapiens hypothetical protein FLJ22865 (FLJ22865), mRNA. /FEA=mRNA /GEN=FLJ22865 /PROD=hypothetical protein FLJ22865 /DB_XREF=gi:13376680 /UG=Hs.288679 hypothetical protein FLJ22865 /FL=gb:NM_025109.1 NM_025109 myosin XIX MYO19 80179 NM_001033579 /// NM_001033580 /// NM_001163735 /// NM_025109 /// XM_005257696 /// XM_005257697 /// XM_006722107 /// XM_006722108 /// XM_006722109 /// XM_006725351 /// XM_006725352 /// XM_006725353 /// XM_006725354 /// XM_006725355 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 219321_at NM_022474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022474.1 /DEF=Homo sapiens hypothetical protein FLJ12615 similar to membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5) (FLJ12615), mRNA. /FEA=mRNA /GEN=FLJ12615 /PROD=hypothetical protein FLJ12615 similar tomembrane protein, palmitoylated 3 (MAGUK p55 subfamilymember 5) /DB_XREF=gi:11968024 /UG=Hs.306219 hypothetical protein FLJ12615 similar to membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5) /FL=gb:NM_022474.1 NM_022474 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) MPP5 64398 NM_001256550 /// NM_022474 /// XM_005268003 0002011 // morphogenesis of an epithelial sheet // inferred from mutant phenotype /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0035750 // protein localization to myelin sheath abaxonal region // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement /// 0090002 // establishment of protein localization to plasma membrane // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 219322_s_at NM_017818 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017818.1 /DEF=Homo sapiens WD repeat domain 8 (WDR8), mRNA. /FEA=mRNA /GEN=WDR8 /PROD=WD repeat domain 8 /DB_XREF=gi:8923402 /UG=Hs.31714 hypothetical protein FLJ20430 /FL=gb:AB034912.1 gb:NM_017818.1 NM_017818 WD repeat containing, antisense to TP73 WRAP73 49856 NM_017818 /// XM_005244754 /// XM_005244755 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219323_s_at NM_005699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005699.1 /DEF=Homo sapiens interleukin 18 binding protein (IL18BP), mRNA. /FEA=mRNA /GEN=IL18BP /PROD=interleukin 18 binding protein /DB_XREF=gi:10835223 /UG=Hs.325978 interleukin 18 binding protein /FL=gb:NM_005699.1 gb:AF110801.1 NM_005699 interleukin 18 binding protein IL18BP 10068 NM_001039659 /// NM_001039660 /// NM_001145055 /// NM_001145057 /// NM_005699 /// NM_173042 /// NM_173043 /// NM_173044 /// XM_005273705 /// XM_006718403 /// XM_006718404 /// XM_006718405 /// XM_006718406 /// XM_006718407 /// XM_006718408 /// XM_006718409 /// XM_006718410 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042088 // T-helper 1 type immune response // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042007 // interleukin-18 binding // inferred from direct assay /// 0048019 // receptor antagonist activity // traceable author statement 219324_at NM_024313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024313.1 /DEF=Homo sapiens hypothetical protein MGC3731 (MGC3731), mRNA. /FEA=mRNA /GEN=MGC3731 /PROD=hypothetical protein MGC3731 /DB_XREF=gi:13236552 /UG=Hs.326372 hypothetical protein MGC3731 /FL=gb:BC002808.1 gb:NM_024313.1 NM_024313 nucleolar protein 12 NOL12 79159 NM_024313 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030047 // actin modification // non-traceable author statement /// 0051016 // barbed-end actin filament capping // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0030496 // midbody // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045159 // myosin II binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from direct assay 219325_s_at NM_018696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018696.1 /DEF=Homo sapiens elaC (E.coli) homolog 1 (ELAC1), mRNA. /FEA=mRNA /GEN=ELAC1 /PROD=elaC (E.coli) homolog 1 /DB_XREF=gi:8922121 /UG=Hs.47572 elaC (E.coli) homolog 1 /FL=gb:AF308695.1 gb:AB029151.1 gb:NM_018696.1 NM_018696 elaC ribonuclease Z 1 ELAC1 55520 NM_018696 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042779 // tRNA 3'-trailer cleavage // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016891 // endoribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219326_s_at NM_006577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006577.2 /DEF=Homo sapiens beta-1,3-N-acetylglucosaminyltransferase (BETA3GNT), mRNA. /FEA=mRNA /GEN=BETA3GNT /PROD=beta-1,3-N-acetylglucosaminyltransferase /DB_XREF=gi:9845237 /UG=Hs.48730 beta-1,3-N-acetylglucosaminyltransferase bGnT-2 /FL=gb:AF288208.1 gb:AF092051.2 gb:NM_006577.2 NM_006577 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 B3GNT2 10678 NM_006577 /// NM_033252 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 219327_s_at NM_022036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022036.1 /DEF=Homo sapiens G protein-coupled receptor, family C, group 5, member C (GPRC5C), transcript variant 1, mRNA. /FEA=mRNA /GEN=GPRC5C /PROD=G protein-coupled receptor, family C, group 5,member C, isoform a, precursor /DB_XREF=gi:13112058 /UG=Hs.58014 G protein-coupled receptor, family C, group 5, member C /FL=gb:NM_022036.1 gb:AF207989.1 NM_022036 G protein-coupled receptor, class C, group 5, member C GPRC5C 55890 NM_018653 /// NM_022036 /// XM_005257512 /// XM_005257513 /// XM_005257514 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 219328_at NM_022779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022779.1 /DEF=Homo sapiens hypothetical protein FLJ13633 (FLJ13633), mRNA. /FEA=mRNA /GEN=FLJ13633 /PROD=hypothetical protein FLJ13633 /DB_XREF=gi:12232466 /UG=Hs.69331 hypothetical protein FLJ13633 /FL=gb:NM_022779.1 NM_022779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 DDX31 64794 NM_022779 /// NM_138620 /// XM_005272206 /// XM_005272207 /// XM_005272208 /// XM_006717236 /// XR_246600 /// XR_428534 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219329_s_at NM_016085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016085.1 /DEF=Homo sapiens apoptosis related protein APR-3 (APR-3), mRNA. /FEA=mRNA /GEN=APR-3 /PROD=apoptosis related protein APR-3 /DB_XREF=gi:7706360 /UG=Hs.9527 apoptosis related protein APR-3 /FL=gb:AF144055.2 gb:NM_016085.1 NM_016085 all-trans retinoic acid-induced differentiation factor ATRAID 51374 NM_001170795 /// NM_016085 /// NM_080592 0010468 // regulation of gene expression // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0033689 // negative regulation of osteoblast proliferation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 2000599 // negative regulation of cyclin catabolic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219330_at NM_024062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024062.1 /DEF=Homo sapiens hypothetical protein MGC5338 (MGC5338), mRNA. /FEA=mRNA /GEN=MGC5338 /PROD=hypothetical protein MGC5338 /DB_XREF=gi:13129037 /UG=Hs.99598 hypothetical protein MGC5338 /FL=gb:BC000907.1 gb:NM_024062.1 NM_024062 VANGL planar cell polarity protein 1 VANGL1 81839 NM_001172411 /// NM_001172412 /// NM_138959 /// XM_006710935 /// XM_006710936 0007275 // multicellular organismal development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219331_s_at NM_018203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018203.1 /DEF=Homo sapiens hypothetical protein FLJ10748 (FLJ10748), mRNA. /FEA=mRNA /GEN=FLJ10748 /PROD=hypothetical protein FLJ10748 /DB_XREF=gi:8922639 /UG=Hs.10414 hypothetical protein FLJ10748 /FL=gb:NM_018203.1 NM_018203 kelch domain containing 8A KLHDC8A 55220 NM_001271863 /// NM_001271864 /// NM_001271865 /// NM_018203 /// XM_006711429 0005515 // protein binding // inferred from electronic annotation 219332_at NM_024723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024723.1 /DEF=Homo sapiens hypothetical protein FLJ23471 (FLJ23471), mRNA. /FEA=mRNA /GEN=FLJ23471 /PROD=hypothetical protein FLJ23471 /DB_XREF=gi:13376030 /UG=Hs.110964 hypothetical protein FLJ23471 /FL=gb:NM_024723.1 NM_024723 MICAL-like 2 MICALL2 79778 NM_024723 /// NM_182924 /// XM_006715774 0006897 // endocytosis // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from sequence or structural similarity /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032432 // actin filament bundle // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0031005 // filamin binding // inferred from direct assay /// 0042805 // actinin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity 219333_s_at NM_023083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023083.1 /DEF=Homo sapiens calpain 10 (CAPN10), transcript variant 1, mRNA. /FEA=mRNA /GEN=CAPN10 /PROD=calpain 10, isoform a /DB_XREF=gi:13186301 /UG=Hs.112218 calpain 10 /FL=gb:AF089088.1 gb:AF089094.1 gb:NM_023083.1 gb:NM_023088.1 gb:BC004260.1 NM_023083 calpain 10 CAPN10 11132 NM_021251 /// NM_023083 /// NM_023084 /// NM_023085 /// NM_023086 /// NM_023087 /// NM_023088 /// NM_023089 0006508 // proteolysis // inferred from mutant phenotype /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // inferred by curator /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032388 // positive regulation of intracellular transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0097050 // type B pancreatic cell apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000676 // positive regulation of type B pancreatic cell apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005623 // cell // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0000149 // SNARE binding // inferred from sequence or structural similarity /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219334_s_at NM_022837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022837.1 /DEF=Homo sapiens hypothetical protein FLJ22833 (FLJ22833), mRNA. /FEA=mRNA /GEN=FLJ22833 /PROD=hypothetical protein FLJ22833 /DB_XREF=gi:12383083 /UG=Hs.118183 hypothetical protein FLJ22833 /FL=gb:NM_022837.1 NM_022837 nucleic acid binding protein 1 NABP1 64859 NM_001031716 /// NM_001254736 /// NM_022837 /// NR_045622 /// NR_045623 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070876 // SOSS complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation 219335_at NM_022838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022838.1 /DEF=Homo sapiens hypothetical protein FLJ12969 (FLJ12969), mRNA. /FEA=mRNA /GEN=FLJ12969 /PROD=hypothetical protein FLJ12969 /DB_XREF=gi:12383085 /UG=Hs.119699 hypothetical protein FLJ12969 /FL=gb:NM_022838.1 NM_022838 armadillo repeat containing, X-linked 5 ARMCX5 64860 NM_001168478 /// NM_001168479 /// NM_001168480 /// NM_001168482 /// NM_001168485 /// NM_022838 0005737 // cytoplasm // inferred from direct assay 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 219336_s_at NM_015947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015947.1 /DEF=Homo sapiens CGI-18 protein (LOC51008), mRNA. /FEA=mRNA /GEN=LOC51008 /PROD=CGI-18 protein /DB_XREF=gi:7705601 /UG=Hs.121599 CGI-18 protein /FL=gb:AY013290.1 gb:AF132952.1 gb:NM_015947.1 NM_015947 activating signal cointegrator 1 complex subunit 1 ASCC1 51008 NM_001198798 /// NM_001198799 /// NM_001198800 /// NM_015947 /// NR_045564 /// XM_005269878 /// XM_006717872 /// XM_006717873 /// XM_006717874 /// XM_006717875 /// XM_006717876 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation 219337_at NM_017891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017891.1 /DEF=Homo sapiens hypothetical protein FLJ20584 (FLJ20584), mRNA. /FEA=mRNA /GEN=FLJ20584 /PROD=hypothetical protein FLJ20584 /DB_XREF=gi:8923546 /UG=Hs.126704 hypothetical protein FLJ20584 /FL=gb:NM_017891.1 NM_017891 chromosome 1 open reading frame 159 C1orf159 54991 NM_017891 /// XM_005244765 /// XM_006710716 /// XM_006710717 /// XM_006710718 /// XM_006710719 /// XM_006710720 /// XM_006710721 /// XR_241033 /// XR_426615 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219338_s_at NM_017691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017691.1 /DEF=Homo sapiens hypothetical protein FLJ20156 (FLJ20156), mRNA. /FEA=mRNA /GEN=FLJ20156 /PROD=hypothetical protein FLJ20156 /DB_XREF=gi:8923153 /UG=Hs.12692 hypothetical protein FLJ20156 /FL=gb:NM_017691.1 NM_017691 leucine rich repeat containing 49 LRRC49 54839 NM_001199017 /// NM_001199018 /// NM_001284357 /// NM_017691 /// XM_005254492 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219339_s_at NM_024757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024757.1 /DEF=Homo sapiens hypothetical protein FLJ12879 (FLJ12879), mRNA. /FEA=mRNA /GEN=FLJ12879 /PROD=hypothetical protein FLJ12879 /DB_XREF=gi:13376092 /UG=Hs.127236 hypothetical protein FLJ12879 /FL=gb:NM_024757.1 NM_024757 euchromatic histone-lysine N-methyltransferase 1 EHMT1 79813 NM_001145527 /// NM_024757 /// XM_005266105 /// XM_005266106 /// XM_005266107 /// XM_005266108 /// XM_005266109 /// XM_005266110 /// XM_005266111 /// XM_006717288 /// XM_006717289 /// XM_006717290 /// XR_245339 /// XR_428538 /// XR_428539 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from direct assay /// 0016571 // histone methylation // inferred from direct assay /// 0018026 // peptidyl-lysine monomethylation // inferred from sequence or structural similarity /// 0018027 // peptidyl-lysine dimethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from sequence or structural similarity /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from sequence or structural similarity 219340_s_at AF123759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123759.1 /DEF=Homo sapiens putative transmembrane protein (CLN8) mRNA, complete cds. /FEA=mRNA /GEN=CLN8 /PROD=putative transmembrane protein /DB_XREF=gi:6467264 /UG=Hs.127675 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) /FL=gb:AF123757.1 gb:AF123759.1 gb:AF123760.1 gb:AF123761.1 gb:NM_018941.1 AF123759 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) CLN8 2055 NM_001034061 /// NM_018941 /// XM_005266021 /// XM_005266022 /// XM_005266023 /// XM_005266024 /// XM_005266025 /// XM_005266026 /// XM_005266027 /// XM_005266028 /// XM_006725753 /// XM_006725754 /// XM_006725755 /// XM_006725756 /// XM_006725757 /// XM_006725758 /// XM_006725759 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0006672 // ceramide metabolic process // inferred from mutant phenotype /// 0006869 // lipid transport // non-traceable author statement /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // non-traceable author statement /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021523 // somatic motor neuron differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0035176 // social behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0044265 // cellular macromolecule catabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // non-traceable author statement /// 0046513 // ceramide biosynthetic process // non-traceable author statement /// 0050881 // musculoskeletal movement // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051348 // negative regulation of transferase activity // inferred from electronic annotation /// 0051935 // L-glutamate uptake involved in synaptic transmission // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 219341_at NM_018941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018941.1 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8), mRNA. /FEA=mRNA /GEN=CLN8 /PROD=ceroid-lipofuscinosis, neuronal 8 (epilepsy,progressive with mental retardation) /DB_XREF=gi:9256526 /UG=Hs.127675 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) /FL=gb:AF123757.1 gb:AF123759.1 gb:AF123760.1 gb:AF123761.1 gb:NM_018941.1 NM_018941 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) CLN8 2055 NM_001034061 /// NM_018941 /// XM_005266021 /// XM_005266022 /// XM_005266023 /// XM_005266024 /// XM_005266025 /// XM_005266026 /// XM_005266027 /// XM_005266028 /// XM_006725753 /// XM_006725754 /// XM_006725755 /// XM_006725756 /// XM_006725757 /// XM_006725758 /// XM_006725759 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0006672 // ceramide metabolic process // inferred from mutant phenotype /// 0006869 // lipid transport // non-traceable author statement /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // non-traceable author statement /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021523 // somatic motor neuron differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0035176 // social behavior // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0044265 // cellular macromolecule catabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // non-traceable author statement /// 0046513 // ceramide biosynthetic process // non-traceable author statement /// 0050881 // musculoskeletal movement // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051348 // negative regulation of transferase activity // inferred from electronic annotation /// 0051935 // L-glutamate uptake involved in synaptic transmission // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 219342_at NM_022900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022900.1 /DEF=Homo sapiens hypothetical protein FLJ21213 (FLJ21213), mRNA. /FEA=mRNA /GEN=FLJ21213 /PROD=hypothetical protein FLJ21213 /DB_XREF=gi:12597638 /UG=Hs.128003 hypothetical protein FLJ21213 /FL=gb:NM_022900.1 NM_022900 CAS1 domain containing 1 CASD1 64921 NM_022900 /// XM_006716092 /// XM_006716093 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219343_at NM_017913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017913.1 /DEF=Homo sapiens hypothetical protein FLJ20639 (FLJ20639), mRNA. /FEA=mRNA /GEN=FLJ20639 /PROD=hypothetical protein FLJ20639 /DB_XREF=gi:8923591 /UG=Hs.128646 hypothetical protein FLJ20639 /FL=gb:NM_017913.1 NM_017913 cell division cycle 37-like 1 CDC37L1 55664 NM_017913 0005737 // cytoplasm // inferred from electronic annotation 219344_at NM_018344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018344.1 /DEF=Homo sapiens hypothetical protein FLJ11160 (FLJ11160), mRNA. /FEA=mRNA /GEN=FLJ11160 /PROD=hypothetical protein FLJ11160 /DB_XREF=gi:8922906 /UG=Hs.129819 hypothetical protein FLJ11160 /FL=gb:AF326987.1 gb:NM_018344.1 NM_018344 solute carrier family 29 (equilibrative nucleoside transporter), member 3 SLC29A3 55315 NM_001174098 /// NM_018344 /// NR_033413 /// NR_033414 /// XM_006717910 0006810 // transport // inferred from electronic annotation /// 0015858 // nucleoside transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 219345_at NM_016074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016074.1 /DEF=Homo sapiens CGI-143 protein (LOC51027), mRNA. /FEA=mRNA /GEN=LOC51027 /PROD=CGI-143 protein /DB_XREF=gi:7705637 /UG=Hs.13880 CGI-143 protein /FL=gb:BC002771.1 gb:AF151901.1 gb:NM_016074.1 NM_016074 bolA family member 1 BOLA1 51027 NM_016074 /// XM_005245233 /// XM_006711348 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 219346_at NM_024509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024509.1 /DEF=Homo sapiens hypothetical protein MGC2656 (MGC2656), mRNA. /FEA=mRNA /GEN=MGC2656 /PROD=hypothetical protein MGC2656 /DB_XREF=gi:13375645 /UG=Hs.143792 hypothetical protein MGC2656 /FL=gb:BC003578.1 gb:NM_024509.1 NM_024509 leucine rich repeat and fibronectin type III domain containing 3 LRFN3 79414 NM_024509 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219347_at NM_018283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018283.1 /DEF=Homo sapiens hypothetical protein FLJ10956 (FLJ10956), mRNA. /FEA=mRNA /GEN=FLJ10956 /PROD=hypothetical protein FLJ10956 /DB_XREF=gi:8922791 /UG=Hs.144407 hypothetical protein FLJ10956 /FL=gb:NM_018283.1 NM_018283 nudix (nucleoside diphosphate linked moiety X)-type motif 15 NUDT15 55270 NM_018283 0006184 // GTP catabolic process // inferred from direct assay /// 0006203 // dGTP catabolic process // inferred from direct assay /// 0034656 // nucleobase-containing small molecule catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0008413 // 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035539 // 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219348_at NM_018467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018467.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS032 (MDS032), mRNA. /FEA=mRNA /GEN=MDS032 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS032 /DB_XREF=gi:8923935 /UG=Hs.16187 uncharacterized hematopoietic stemprogenitor cells protein MDS032 /FL=gb:AF220052.1 gb:NM_018467.1 NM_018467 unconventional SNARE in the ER 1 homolog (S. cerevisiae) USE1 55850 NM_018467 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007041 // lysosomal transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from sequence or structural similarity /// 0032940 // secretion by cell // inferred from sequence or structural similarity /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from electronic annotation 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219349_s_at NM_018303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018303.1 /DEF=Homo sapiens hypothetical protein FLJ11026 (FLJ11026), mRNA. /FEA=mRNA /GEN=FLJ11026 /PROD=hypothetical protein FLJ11026 /DB_XREF=gi:8922829 /UG=Hs.16580 hypothetical protein FLJ11026 /FL=gb:NM_018303.1 NM_018303 exocyst complex component 2 EXOC2 55770 NM_018303 /// NR_073064 /// XM_006715141 /// XM_006715142 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006893 // Golgi to plasma membrane transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017160 // Ral GTPase binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 219350_s_at NM_019887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019887.1 /DEF=Homo sapiens second mitochondria-derived activator of caspase (SMAC), mRNA. /FEA=mRNA /GEN=SMAC /PROD=second mitochondria-derived activator ofcaspase /DB_XREF=gi:9845296 /UG=Hs.169611 second mitochondria-derived activator of caspase /FL=gb:AF262240.1 gb:NM_019887.1 NM_019887 diablo, IAP-binding mitochondrial protein DIABLO 56616 NM_001278302 /// NM_001278303 /// NM_001278304 /// NM_001278342 /// NM_019887 /// NM_138929 /// NM_138930 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 219351_at NM_014563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014563.1 /DEF=Homo sapiens spondyloepiphyseal dysplasia, late (SEDL), mRNA. /FEA=mRNA /GEN=SEDL /PROD=spondyloepiphyseal dysplasia, late /DB_XREF=gi:7657547 /UG=Hs.174038 spondyloepiphyseal dysplasia, late /FL=gb:NM_014563.1 NM_014563 trafficking protein particle complex 2 TRAPPC2 6399 NM_001011658 /// NM_001128835 /// NM_014563 0001501 // skeletal system development // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction 219352_at NM_017912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017912.1 /DEF=Homo sapiens hypothetical protein FLJ20637 (FLJ20637), mRNA. /FEA=mRNA /GEN=FLJ20637 /PROD=hypothetical protein FLJ20637 /DB_XREF=gi:8923589 /UG=Hs.179669 hypothetical protein FLJ20637 /FL=gb:NM_017912.1 NM_017912 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 HERC6 55008 NM_001013000 /// NM_001013002 /// NM_001013005 /// NM_001165136 /// NM_017912 /// XM_005263083 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0016874 // ligase activity // inferred from electronic annotation 219353_at NM_017687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017687.1 /DEF=Homo sapiens hypothetical protein FLJ20147 (FLJ20147), mRNA. /FEA=mRNA /GEN=FLJ20147 /PROD=hypothetical protein FLJ20147 /DB_XREF=gi:8923144 /UG=Hs.23984 hypothetical protein FLJ20147 /FL=gb:NM_017687.1 NM_017687 NHL repeat containing 2 NHLRC2 374354 NM_198514 0005515 // protein binding // inferred from electronic annotation 219354_at NM_018316 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018316.1 /DEF=Homo sapiens hypothetical protein FLJ11078 (FLJ11078), mRNA. /FEA=mRNA /GEN=FLJ11078 /PROD=hypothetical protein FLJ11078 /DB_XREF=gi:8922853 /UG=Hs.250632 hypothetical protein FLJ11078 /FL=gb:NM_018316.1 NM_018316 kelch-like family member 26 KLHL26 55295 NM_018316 /// XM_006722785 0005515 // protein binding // inferred from electronic annotation 219355_at NM_018015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018015.2 /DEF=Homo sapiens hypothetical protein FLJ10178 (FLJ10178), mRNA. /FEA=mRNA /GEN=FLJ10178 /PROD=hypothetical protein FLJ10178 /DB_XREF=gi:13443025 /UG=Hs.274267 hypothetical protein FLJ10178 /FL=gb:NM_018015.2 NM_018015 chromosome X open reading frame 57 CXorf57 55086 NM_001184782 /// NM_018015 0044822 // poly(A) RNA binding // inferred from direct assay 219356_s_at NM_016410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016410.1 /DEF=Homo sapiens hypothetical protein (HSPC177), mRNA. /FEA=mRNA /GEN=HSPC177 /PROD=hypothetical protein /DB_XREF=gi:7705488 /UG=Hs.279777 hypothetical protein /FL=gb:AF161525.1 gb:NM_016410.1 NM_016410 charged multivesicular body protein 5 CHMP5 51510 NM_001195536 /// NM_016410 0001919 // regulation of receptor recycling // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219357_at NM_014027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014027.1 /DEF=Homo sapiens HSPC018 protein (HSPC018), mRNA. /FEA=mRNA /GEN=HSPC018 /PROD=HSPC018 protein /DB_XREF=gi:7661735 /UG=Hs.279853 HSPC018 protein /FL=gb:BC001701.1 gb:AF077204.1 gb:NM_014027.1 NM_014027 GTP binding protein 1 GTPBP1 9567 NM_004286 /// XM_005261857 /// XR_244397 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0061014 // positive regulation of mRNA catabolic process // inferred from sequence or structural similarity 0000177 // cytoplasmic exosome (RNase complex) // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219358_s_at NM_018404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018404.1 /DEF=Homo sapiens centaurin-alpha 2 protein (HSA272195), mRNA. /FEA=mRNA /GEN=HSA272195 /PROD=centaurin-alpha 2 protein /DB_XREF=gi:8923762 /UG=Hs.28802 centaurin-alpha 2 protein /FL=gb:NM_018404.1 NM_018404 ArfGAP with dual PH domains 2 ADAP2 55803 NM_018404 /// XM_005258008 /// XM_005258011 /// XM_006721973 0007507 // heart development // inferred from expression pattern /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from sequence or structural similarity /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219359_at NM_025092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025092.1 /DEF=Homo sapiens hypothetical protein FLJ22635 (FLJ22635), mRNA. /FEA=mRNA /GEN=FLJ22635 /PROD=hypothetical protein FLJ22635 /DB_XREF=gi:13376651 /UG=Hs.288529 hypothetical protein FLJ22635 /FL=gb:NM_025092.1 NM_025092 ATH1, acid trehalase-like 1 (yeast) ATHL1 80162 NM_025092 /// XM_006718330 /// XM_006718331 /// XM_006718332 /// XM_006718333 /// XM_006718334 /// XM_006718335 /// XM_006718336 /// XR_428853 /// XR_428854 /// XR_428855 /// XR_428856 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 219360_s_at NM_017636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017636.1 /DEF=Homo sapiens hypothetical protein FLJ20041 (FLJ20041), mRNA. /FEA=mRNA /GEN=FLJ20041 /PROD=hypothetical protein FLJ20041 /DB_XREF=gi:8923048 /UG=Hs.31608 hypothetical protein FLJ20041 /FL=gb:NM_017636.1 NM_017636 transient receptor potential cation channel, subfamily M, member 4 TRPM4 54795 NM_001195227 /// NM_017636 /// XM_005259017 /// XM_005259018 /// XM_006723249 0002376 // immune system process // inferred from electronic annotation /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002724 // regulation of T cell cytokine production // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005227 // calcium activated cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 219361_s_at NM_022767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022767.1 /DEF=Homo sapiens hypothetical protein FLJ12484 (FLJ12484), mRNA. /FEA=mRNA /GEN=FLJ12484 /PROD=hypothetical protein FLJ12484 /DB_XREF=gi:12232442 /UG=Hs.37747 hypothetical protein FLJ12484 /FL=gb:NM_022767.1 NM_022767 apoptosis enhancing nuclease AEN 64782 NM_022767 /// XM_005254966 /// XM_005254967 /// XM_006720644 /// XM_006720645 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 219362_at NM_024635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024635.1 /DEF=Homo sapiens hypothetical protein FLJ22643 (FLJ22643), mRNA. /FEA=mRNA /GEN=FLJ22643 /PROD=hypothetical protein FLJ22643 /DB_XREF=gi:13375865 /UG=Hs.43579 hypothetical protein FLJ22643 /FL=gb:NM_024635.1 NM_024635 N(alpha)-acetyltransferase 35, NatC auxiliary subunit NAA35 60560 NM_024635 /// XM_005252126 /// XM_005252127 /// XM_005252128 /// XM_006717231 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0048659 // smooth muscle cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005844 // polysome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031417 // NatC complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation 219363_s_at NM_015942 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015942.1 /DEF=Homo sapiens CGI-12 protein (LOC51001), mRNA. /FEA=mRNA /GEN=LOC51001 /PROD=CGI-12 protein /DB_XREF=gi:7705587 /UG=Hs.46680 CGI-12 protein /FL=gb:AF132946.1 gb:NM_015942.1 NM_015942 mitochondrial transcription termination factor 3 MTERF3 51001 NM_001286643 /// NM_015942 /// XM_005250926 /// XM_005250927 /// XM_006716568 /// XM_006716569 /// XM_006716570 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 219364_at NM_024119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024119.1 /DEF=Homo sapiens hypothetical protein FLJ11354 (FLJ11354), mRNA. /FEA=mRNA /GEN=FLJ11354 /PROD=hypothetical protein FLJ11354 /DB_XREF=gi:13129141 /UG=Hs.55918 hypothetical protein FLJ11354 /FL=gb:NM_024119.1 NM_024119 DEXH (Asp-Glu-X-His) box polypeptide 58 DHX58 79132 NM_024119 /// XR_243681 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // inferred from sequence or structural similarity /// 0039534 // negative regulation of MDA-5 signaling pathway // inferred from mutant phenotype /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from direct assay /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from direct assay /// 0045824 // negative regulation of innate immune response // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900245 // positive regulation of MDA-5 signaling pathway // inferred from sequence or structural similarity /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219365_s_at NM_024046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024046.1 /DEF=Homo sapiens hypothetical protein MGC8407 (MGC8407), mRNA. /FEA=mRNA /GEN=MGC8407 /PROD=hypothetical protein MGC8407 /DB_XREF=gi:13129007 /UG=Hs.6262 hypothetical protein MGC8407 /FL=gb:BC000497.1 gb:BC001921.1 gb:NM_024046.1 NM_024046 CaM kinase-like vesicle-associated CAMKV 79012 NM_024046 /// XM_005265478 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219366_at NM_020371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020371.1 /DEF=Homo sapiens cell death regulator aven (LOC57099), mRNA. /FEA=mRNA /GEN=LOC57099 /PROD=cell death regulator aven /DB_XREF=gi:9966840 /UG=Hs.63168 cell death regulator aven /FL=gb:AF283508.1 gb:NM_020371.1 NM_020371 apoptosis, caspase activation inhibitor AVEN 57099 NM_020371 /// XM_005254563 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219367_s_at NM_018534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018534.1 /DEF=Homo sapiens hypothetical protein PRO2714 (PRO2714), mRNA. /FEA=mRNA /GEN=PRO2714 /PROD=hypothetical protein PRO2714 /DB_XREF=gi:8924189 /UG=Hs.63382 hypothetical protein PRO2714 /FL=gb:NM_018534.1 NM_018534 neuropilin 2 NRP2 8828 NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934 0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219368_at NM_021963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021963.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 2 (NAP1L2), mRNA. /FEA=mRNA /GEN=NAP1L2 /PROD=nucleosome assembly protein 1-like 2 /DB_XREF=gi:11415047 /UG=Hs.66180 nucleosome assembly protein 1-like 2 /FL=gb:NM_021963.1 gb:AB027013.1 NM_021963 nucleosome assembly protein 1-like 2 NAP1L2 4674 NM_021963 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219369_s_at NM_023112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023112.1 /DEF=Homo sapiens hypothetical protein FLJ21916 (FLJ21916), mRNA. /FEA=mRNA /GEN=FLJ21916 /PROD=hypothetical protein FLJ21916 /DB_XREF=gi:12962938 /UG=Hs.90034 hypothetical protein FLJ21916 /FL=gb:BC000208.1 gb:NM_023112.1 NM_023112 OTU deubiquitinase, ubiquitin aldehyde binding 2 OTUB2 78990 NM_023112 /// XM_005268055 /// XM_006725171 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219370_at NM_019845 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019845.1 /DEF=Homo sapiens candidate mediator of the p53-dependent G2 arrest (REPRIMO), mRNA. /FEA=mRNA /GEN=REPRIMO /PROD=candidate mediator of the p53-dependent G2arrest /DB_XREF=gi:9790192 /UG=Hs.100890 candidate mediator of the p53-dependent G2 arrest /FL=gb:BC002908.1 gb:AB043585.1 gb:NM_019845.1 NM_019845 reprimo, TP53 dependent G2 arrest mediator candidate RPRM 56475 NM_019845 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219371_s_at NM_016270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016270.1 /DEF=Homo sapiens Kruppel-like factor (LOC51713), mRNA. /FEA=mRNA /GEN=LOC51713 /PROD=Kruppel-like factor /DB_XREF=gi:7706468 /UG=Hs.107740 Kruppel-like factor 2 (lung) /FL=gb:AF134053.1 gb:AF205849.1 gb:NM_016270.1 NM_016270 Kruppel-like factor 2 KLF2 10365 NM_016270 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071409 // cellular response to cycloheximide // inferred from electronic annotation /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219372_at NM_014055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014055.1 /DEF=Homo sapiens CDV-1 protein (CDV-1), mRNA. /FEA=mRNA /GEN=CDV-1 /PROD=CDV-1 protein /DB_XREF=gi:7661539 /UG=Hs.108881 CDV-1 protein /FL=gb:AF078932.1 gb:NM_014055.1 NM_014055 intraflagellar transport 81 homolog (Chlamydomonas) IFT81 28981 NM_001143779 /// NM_014055 /// NM_031473 /// XR_429093 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype 0005813 // centrosome // not recorded /// 0005929 // cilium // not recorded /// 0030992 // intraciliary transport particle B // not recorded /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0015631 // tubulin binding // inferred from direct assay 219373_at NM_018973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018973.1 /DEF=Homo sapiens dolichyl-phosphate mannosyltransferase polypeptide 3 (DPM3), mRNA. /FEA=mRNA /GEN=DPM3 /PROD=dolichyl-phosphate mannosyltransferasepolypeptide 3 /DB_XREF=gi:9506552 /UG=Hs.110477 dolichyl-phosphate mannosyltransferase polypeptide 3 /FL=gb:AF312923.1 gb:AF312922.1 gb:AB028128.1 gb:NM_018973.1 NM_018973 dolichyl-phosphate mannosyltransferase polypeptide 3 DPM3 54344 NM_018973 /// NM_153741 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0018406 // protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan // traceable author statement /// 0031647 // regulation of protein stability // inferred from physical interaction /// 0035268 // protein mannosylation // traceable author statement /// 0035269 // protein O-linked mannosylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0031501 // mannosyltransferase complex // traceable author statement /// 0033185 // dolichol-phosphate-mannose synthase complex // inferred from direct assay 0004582 // dolichyl-phosphate beta-D-mannosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 219374_s_at NM_024740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024740.1 /DEF=Homo sapiens hypothetical protein FLJ21845 (FLJ21845), mRNA. /FEA=mRNA /GEN=FLJ21845 /PROD=hypothetical protein FLJ21845 /DB_XREF=gi:13376061 /UG=Hs.120824 hypothetical protein FLJ21845 /FL=gb:NM_024740.1 NM_024740 ALG9, alpha-1,2-mannosyltransferase ALG9 79796 NM_001077690 /// NM_001077691 /// NM_001077692 /// NM_024740 /// XM_005277723 /// XM_005277724 /// XM_006718913 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0052918 // dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity // inferred from electronic annotation /// 0052926 // dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity // inferred from electronic annotation 219375_at NM_006090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006090.1 /DEF=Homo sapiens cholineethanolaminephosphotransferase (CEPT1), mRNA. /FEA=mRNA /GEN=CEPT1 /PROD=cholineethanolaminephosphotransferase /DB_XREF=gi:5174414 /UG=Hs.125031 cholineethanolaminephosphotransferase /FL=gb:AF068302.1 gb:NM_006090.1 NM_006090 choline/ethanolamine phosphotransferase 1 CEPT1 10390 NM_001007794 /// NM_006090 /// XM_005270353 /// XM_006710285 /// XM_006710286 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004142 // diacylglycerol cholinephosphotransferase activity // traceable author statement /// 0004307 // ethanolaminephosphotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219376_at NM_024639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024639.1 /DEF=Homo sapiens hypothetical protein FLJ23393 (FLJ23393), mRNA. /FEA=mRNA /GEN=FLJ23393 /PROD=hypothetical protein FLJ23393 /DB_XREF=gi:13375873 /UG=Hs.126280 hypothetical protein FLJ23393 /FL=gb:NM_024639.1 NM_024639 zinc finger protein 322 ZNF322 79692 NM_001242797 /// NM_001242798 /// NM_001242799 /// NM_024639 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219377_at NM_022751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022751.1 /DEF=Homo sapiens hypothetical protein FLJ21610 (FLJ21610), mRNA. /FEA=mRNA /GEN=FLJ21610 /PROD=hypothetical protein FLJ21610 /DB_XREF=gi:12232414 /UG=Hs.12727 hypothetical protein FLJ21610 /FL=gb:NM_022751.1 NM_022751 GRB2 associated, regulator of MAPK1 GAREM 64762 NM_001242409 /// NM_022751 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay 0005886 // plasma membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay 219378_at NM_024561 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024561.1 /DEF=Homo sapiens hypothetical protein FLJ22054 (FLJ22054), mRNA. /FEA=mRNA /GEN=FLJ22054 /PROD=hypothetical protein FLJ22054 /DB_XREF=gi:13375728 /UG=Hs.13277 hypothetical protein FLJ22054 /FL=gb:NM_024561.1 NM_024561 N(alpha)-acetyltransferase 16, NatA auxiliary subunit NAA16 79612 NM_001110798 /// NM_018527 /// NM_024561 /// XM_005266522 /// XM_005266523 /// XM_006719866 /// XR_245394 /// XR_429219 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay /// 0006474 // N-terminal protein amino acid acetylation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0031415 // NatA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016407 // acetyltransferase activity // inferred from sequence or structural similarity /// 0043022 // ribosome binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from sequence or structural similarity 219379_x_at NM_018083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018083.1 /DEF=Homo sapiens hypothetical protein FLJ10390 (FLJ10390), mRNA. /FEA=mRNA /GEN=FLJ10390 /PROD=hypothetical protein FLJ10390 /DB_XREF=gi:8922400 /UG=Hs.133475 hypothetical protein FLJ10390 /FL=gb:NM_018083.1 NM_018083 zinc finger protein 358 ZNF358 140467 NM_018083 /// XM_005272460 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from sequence or structural similarity /// 0035115 // embryonic forelimb morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219380_x_at NM_006502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006502.1 /DEF=Homo sapiens polymerase (DNA directed), eta (POLH), mRNA. /FEA=mRNA /GEN=POLH /PROD=polymerase (DNA directed), eta /DB_XREF=gi:5729981 /UG=Hs.155573 polymerase (DNA directed), eta /FL=gb:AB024313.1 gb:AF158185.1 gb:NM_006502.1 NM_006502 polymerase (DNA directed), eta POLH 5429 NM_001291969 /// NM_001291970 /// NM_006502 /// XM_005249186 /// XM_006715118 0000731 // DNA synthesis involved in DNA repair // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006301 // postreplication repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219381_at NM_023073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023073.1 /DEF=Homo sapiens hypothetical protein FLJ13231 (FLJ13231), mRNA. /FEA=mRNA /GEN=FLJ13231 /PROD=hypothetical protein FLJ13231 /DB_XREF=gi:12751482 /UG=Hs.156148 hypothetical protein FLJ13231 /FL=gb:NM_023073.1 NM_023073 chromosome 5 open reading frame 42 C5orf42 65250 NM_023073 /// XM_005248345 /// XM_005248346 /// XM_005248347 /// XM_005248349 /// XM_005248350 /// XM_005248353 /// XM_006714489 /// XM_006714490 /// XM_006714491 /// XR_241711 /// XR_427661 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219382_at NM_013368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013368.1 /DEF=Homo sapiens RPA-binding trans-activator (RBT1), mRNA. /FEA=mRNA /GEN=RBT1 /PROD=RPA-binding trans-activator /DB_XREF=gi:7019514 /UG=Hs.169138 RPA-binding trans-activator /FL=gb:AF192529.1 gb:NM_013368.1 NM_013368 SERTA domain containing 3 SERTAD3 29946 NM_013368 /// NM_203344 /// XM_005258832 /// XM_006723179 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219383_at NM_024841 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024841.1 /DEF=Homo sapiens hypothetical protein FLJ14213 (FLJ14213), mRNA. /FEA=mRNA /GEN=FLJ14213 /PROD=hypothetical protein FLJ14213 /DB_XREF=gi:13376254 /UG=Hs.183506 hypothetical protein FLJ14213 /FL=gb:NM_024841.1 NM_024841 proline rich 5 like PRR5L 79899 NM_001160167 /// NM_001160168 /// NM_001160169 /// NM_024841 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010762 // regulation of fibroblast migration // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from direct assay /// 0038203 // TORC2 signaling // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from direct assay 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 219384_s_at NM_012091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012091.2 /DEF=Homo sapiens adenosine deaminase, tRNA-specific 1 (ADAT1), mRNA. /FEA=mRNA /GEN=ADAT1 /PROD=adenosine deaminase, tRNA-specific 1 /DB_XREF=gi:7382475 /UG=Hs.188661 adenosine deaminase, tRNA-specific 1 /FL=gb:BC002758.1 gb:AF125188.1 gb:NM_012091.2 NM_012091 adenosine deaminase, tRNA-specific 1 ADAT1 23536 NM_012091 /// NR_036460 0006396 // RNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from mutant phenotype 0003723 // RNA binding // inferred from mutant phenotype /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0008251 // tRNA-specific adenosine deaminase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219385_at NM_020125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020125.1 /DEF=Homo sapiens BCM-like membrane protein precursor (SBBI42), mRNA. /FEA=mRNA /GEN=SBBI42 /PROD=BCM-like membrane protein precursor /DB_XREF=gi:9910341 /UG=Hs.20450 BCM-like membrane protein precursor /FL=gb:AF144235.1 gb:NM_014036.1 gb:AF146761.1 gb:NM_020125.1 NM_020125 SLAM family member 8 SLAMF8 56833 NM_020125 /// XM_005245345 /// XM_006711456 /// XM_006711457 /// XM_006711458 0033860 // regulation of NAD(P)H oxidase activity // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043549 // regulation of kinase activity // inferred from electronic annotation /// 0090383 // phagosome acidification // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation 219386_s_at NM_020125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020125.1 /DEF=Homo sapiens BCM-like membrane protein precursor (SBBI42), mRNA. /FEA=mRNA /GEN=SBBI42 /PROD=BCM-like membrane protein precursor /DB_XREF=gi:9910341 /UG=Hs.20450 BCM-like membrane protein precursor /FL=gb:AF144235.1 gb:NM_014036.1 gb:AF146761.1 gb:NM_020125.1 NM_020125 SLAM family member 8 SLAMF8 56833 NM_020125 /// XM_005245345 /// XM_006711456 /// XM_006711457 /// XM_006711458 0033860 // regulation of NAD(P)H oxidase activity // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043549 // regulation of kinase activity // inferred from electronic annotation /// 0090383 // phagosome acidification // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219387_at NM_017571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017571.1 /DEF=Homo sapiens hypothetical protein (LOC55580), mRNA. /FEA=mRNA /GEN=LOC55580 /PROD=hypothetical protein /DB_XREF=gi:8923837 /UG=Hs.254122 hypothetical protein /FL=gb:NM_017571.1 NM_017571 coiled-coil domain containing 88A CCDC88A 55704 NM_001135597 /// NM_001254943 /// NM_018084 /// XM_005264418 /// XM_005264421 /// XM_005264423 /// XM_005264426 /// XM_005264427 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031929 // TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction 219388_at NM_024915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024915.1 /DEF=Homo sapiens hypothetical protein FLJ13782 (FLJ13782), mRNA. /FEA=mRNA /GEN=FLJ13782 /PROD=hypothetical protein FLJ13782 /DB_XREF=gi:13376381 /UG=Hs.257924 hypothetical protein FLJ13782 /FL=gb:NM_024915.1 NM_024915 grainyhead-like 2 (Drosophila) GRHL2 79977 NM_024915 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 219389_at NM_017982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017982.1 /DEF=Homo sapiens hypothetical protein FLJ10052 (FLJ10052), mRNA. /FEA=mRNA /GEN=FLJ10052 /PROD=hypothetical protein FLJ10052 /DB_XREF=gi:8922205 /UG=Hs.26244 hypothetical protein FLJ10052 /FL=gb:NM_017982.1 NM_017982 sushi domain containing 4 SUSD4 55061 NM_001037175 /// NM_017982 /// XM_005273169 /// XM_005273171 /// XM_005273172 /// XM_005273173 /// XM_006711408 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219390_at NM_017946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017946.1 /DEF=Homo sapiens hypothetical protein FLJ20731 (FLJ20731), mRNA. /FEA=mRNA /GEN=FLJ20731 /PROD=hypothetical protein FLJ20731 /DB_XREF=gi:8923658 /UG=Hs.264636 hypothetical protein FLJ20731 /FL=gb:BC005206.1 gb:NM_017946.1 NM_017946 FK506 binding protein 14, 22 kDa FKBP14 55033 NM_017946 /// NR_046478 /// NR_046479 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0018208 // peptidyl-proline modification // /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061077 // chaperone-mediated protein folding // not recorded 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219391_at NM_006085 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006085.1 /DEF=Homo sapiens 3(2), 5-bisphosphate nucleotidase 1 (BPNT1), mRNA. /FEA=mRNA /GEN=BPNT1 /PROD=3(2), 5-bisphosphate nucleotidase 1 /DB_XREF=gi:5174398 /UG=Hs.271752 3(2), 5-bisphosphate nucleotidase 1 /FL=gb:AF125042.1 gb:NM_006085.1 NM_006085 3'(2'), 5'-bisphosphate nucleotidase 1 BPNT1 10380 NM_001286149 /// NM_001286150 /// NM_001286151 /// NM_006085 /// XM_005272998 /// XM_005272999 /// XM_005273000 /// XM_005273004 /// XM_005273005 /// XM_006711114 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004441 // inositol-1,4-bisphosphate 1-phosphatase activity // inferred from electronic annotation /// 0008441 // 3'(2'),5'-bisphosphate nucleotidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219392_x_at NM_018304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018304.1 /DEF=Homo sapiens hypothetical protein FLJ11029 (FLJ11029), mRNA. /FEA=mRNA /GEN=FLJ11029 /PROD=hypothetical protein FLJ11029 /DB_XREF=gi:8922831 /UG=Hs.274448 hypothetical protein FLJ11029 /FL=gb:NM_018304.1 NM_018304 proline rich 11 PRR11 55771 NM_018304 /// XR_243671 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 219393_s_at NM_005465 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005465.1 /DEF=Homo sapiens v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (AKT3), mRNA. /FEA=mRNA /GEN=AKT3 /PROD=v-akt murine thymoma viral oncogene homolog 3(protein kinase B, gamma) /DB_XREF=gi:4885548 /UG=Hs.278582 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) /FL=gb:AF135794.1 gb:AF124141.1 gb:NM_005465.1 NM_005465 v-akt murine thymoma viral oncogene homolog 3 AKT3 10000 NM_001206729 /// NM_005465 /// NM_181690 /// XM_005272994 /// XM_005272995 /// XM_005272997 /// XM_006711725 /// XM_006711726 /// XM_006724959 /// XM_006724960 /// XM_006724961 /// XM_006724962 /// XM_006724963 0000002 // mitochondrial genome maintenance // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219394_at NM_024419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024419.1 /DEF=Homo sapiens Phosphatidylglycerophosphate Synthase (PGS1), mRNA. /FEA=mRNA /GEN=PGS1 /PROD=Phosphatidylglycerophosphate Synthase /DB_XREF=gi:13259369 /UG=Hs.278682 Phosphatidylglycerophosphate Synthase /FL=gb:NM_024419.1 NM_024419 phosphatidylglycerophosphate synthase 1 PGS1 9489 NM_024419 /// NR_110601 /// NR_110602 /// NR_111989 /// XM_005257832 /// XM_005257833 /// XR_243691 /// XR_429928 /// XR_429929 /// XR_429930 /// XR_429931 /// XR_429932 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // inferred from sequence or structural similarity /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032049 // cardiolipin biosynthetic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046339 // diacylglycerol metabolic process // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0008444 // CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation 219395_at NM_024939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024939.1 /DEF=Homo sapiens hypothetical protein FLJ21918 (FLJ21918), mRNA. /FEA=mRNA /GEN=FLJ21918 /PROD=hypothetical protein FLJ21918 /DB_XREF=gi:13435148 /UG=Hs.282093 hypothetical protein FLJ21918 /FL=gb:NM_024939.1 NM_024939 epithelial splicing regulatory protein 2 /// microRNA 6773 ESRP2 /// MIR6773 80004 /// 102466194 NM_024939 /// NR_106831 /// XM_005256153 /// XM_006721273 /// XM_006721274 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219396_s_at NM_024608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024608.1 /DEF=Homo sapiens hypothetical protein FLJ22402 (FLJ22402), mRNA. /FEA=mRNA /GEN=FLJ22402 /PROD=hypothetical protein FLJ22402 /DB_XREF=gi:13375816 /UG=Hs.28355 hypothetical protein FLJ22402 /FL=gb:NM_024608.1 NM_024608 microRNA 631 /// nei endonuclease VIII-like 1 (E. coli) MIR631 /// NEIL1 79661 /// 693216 NM_001256552 /// NM_024608 /// NR_030360 /// NR_046311 /// XM_005254659 /// XM_006720677 /// XM_006720678 /// XM_006720679 /// XM_006720680 /// XM_006720681 /// XM_006720682 /// XR_243127 /// XR_429471 /// XR_429472 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0032074 // negative regulation of nuclease activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from direct assay /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from electronic annotation 219397_at NM_025147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025147.1 /DEF=Homo sapiens hypothetical protein FLJ13448 (FLJ13448), mRNA. /FEA=mRNA /GEN=FLJ13448 /PROD=hypothetical protein FLJ13448 /DB_XREF=gi:13376736 /UG=Hs.288945 hypothetical protein FLJ13448 /FL=gb:NM_025147.1 NM_025147 coenzyme Q10 homolog B (S. cerevisiae) COQ10B 80219 NM_025147 /// XM_006712776 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 219398_at NM_022094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022094.1 /DEF=Homo sapiens hypothetical protein FLJ20871 similar to FSP27 (FLJ20871), mRNA. /FEA=mRNA /GEN=FLJ20871 /PROD=hypothetical protein FLJ20871 similar to FSP27 /DB_XREF=gi:11545806 /UG=Hs.301002 hypothetical protein FLJ20871 similar to FSP27 /FL=gb:NM_022094.1 NM_022094 cell death-inducing DFFA-like effector c CIDEC 63924 NM_001199551 /// NM_001199552 /// NM_001199623 /// NM_022094 /// XM_005265374 /// XM_005265375 /// XM_005265376 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // not recorded /// 0097194 // execution phase of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005811 // lipid particle // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 219399_at NM_018362 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018362.1 /DEF=Homo sapiens likely ortholog of mouse LIN-7C; mammalian LIN-7 protein 3 (LIN-7-C), mRNA. /FEA=mRNA /GEN=LIN-7-C /PROD=LIN-7 protein 3 /DB_XREF=gi:8922943 /UG=Hs.306206 LIN-7 protein 3 /FL=gb:NM_018362.1 NM_018362 lin-7 homolog C (C. elegans) LIN7C 55327 NM_018362 0002011 // morphogenesis of an epithelial sheet // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0097016 // L27 domain binding // inferred from direct assay 219400_at NM_003632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003632.1 /DEF=Homo sapiens contactin associated protein 1 (CNTNAP1), mRNA. /FEA=mRNA /GEN=CNTNAP1 /PROD=neurexin 4 /DB_XREF=gi:4505462 /UG=Hs.31622 contactin associated protein 1 /FL=gb:U87223.1 gb:NM_003632.1 NM_003632 contactin associated protein 1 CNTNAP1 8506 NM_003632 /// XM_005257748 /// XM_006722141 /// XM_006722142 0002175 // protein localization to paranode region of axon // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008088 // axon cargo transport // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0019227 // neuronal action potential propagation // inferred from sequence or structural similarity /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0033270 // paranode region of axon // inferred from sequence or structural similarity 0004872 // receptor activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity 219401_at NM_022167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022167.1 /DEF=Homo sapiens xylosyltransferase II (XT2), mRNA. /FEA=mRNA /GEN=XT2 /PROD=xylosyltransferase II /DB_XREF=gi:11545913 /UG=Hs.32117 xylosyltransferase II /FL=gb:NM_022167.1 NM_022167 xylosyltransferase II XYLT2 64132 NM_022167 /// NR_110010 /// XM_005257572 0006024 // glycosaminoglycan biosynthetic process // non-traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030158 // protein xylosyltransferase activity // non-traceable author statement 219402_s_at NM_024295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024295.1 /DEF=Homo sapiens hypothetical protein MGC3067 (MGC3067), mRNA. /FEA=mRNA /GEN=MGC3067 /PROD=hypothetical protein MGC3067 /DB_XREF=gi:13236515 /UG=Hs.323114 hypothetical protein MGC3067 /FL=gb:BC002457.1 gb:NM_024295.1 NM_024295 derlin 1 DERL1 79139 NM_001134671 /// NM_024295 /// XM_006716657 0006810 // transport // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype /// 0034620 // cellular response to unfolded protein // inferred from electronic annotation /// 0045184 // establishment of protein localization // traceable author statement 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // inferred from direct assay 219403_s_at NM_006665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006665.1 /DEF=Homo sapiens heparanase (HPSE), mRNA. /FEA=mRNA /GEN=HPSE /PROD=heparanase /DB_XREF=gi:5729872 /UG=Hs.44227 heparanase /FL=gb:AF165154.1 gb:AF152376.1 gb:NM_006665.1 gb:AF084467.1 gb:AF155510.1 NM_006665 heparanase HPSE 10855 NM_001098540 /// NM_001166498 /// NM_001199830 /// NM_006665 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006029 // proteoglycan metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030200 // heparan sulfate proteoglycan catabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051797 // regulation of hair follicle development // inferred from direct assay /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0061042 // vascular wound healing // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004566 // beta-glucuronidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030305 // heparanase activity // inferred from direct assay /// 0030305 // heparanase activity // traceable author statement /// 0045545 // syndecan binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 219404_at NM_024526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024526.1 /DEF=Homo sapiens hypothetical protein FLJ21522 (FLJ21522), mRNA. /FEA=mRNA /GEN=FLJ21522 /PROD=hypothetical protein FLJ21522 /DB_XREF=gi:13375671 /UG=Hs.5366 hypothetical protein FLJ21522 /FL=gb:NM_024526.1 NM_024526 EPS8-like 3 EPS8L3 79574 NM_024526 /// NM_133181 /// NM_139053 /// XM_006710894 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219405_at NM_018073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018073.1 /DEF=Homo sapiens hypothetical protein FLJ10369 (FLJ10369), mRNA. /FEA=mRNA /GEN=FLJ10369 /PROD=hypothetical protein FLJ10369 /DB_XREF=gi:8922379 /UG=Hs.53940 hypothetical protein FLJ10369 /FL=gb:NM_018073.1 NM_018073 tripartite motif containing 68 TRIM68 55128 NM_018073 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 219406_at NM_024097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024097.1 /DEF=Homo sapiens hypothetical protein MGC955 (MGC955), mRNA. /FEA=mRNA /GEN=MGC955 /PROD=hypothetical protein MGC955 /DB_XREF=gi:13129101 /UG=Hs.55608 hypothetical protein MGC955 /FL=gb:BC001711.1 gb:NM_024097.1 NM_024097 chromosome 1 open reading frame 50 C1orf50 79078 NM_024097 /// NR_040733 0003824 // catalytic activity // inferred from electronic annotation 219407_s_at NM_006059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006059.1 /DEF=Homo sapiens laminin, gamma 3 (LAMC3), mRNA. /FEA=mRNA /GEN=LAMC3 /PROD=laminin, gamma 3 precursor /DB_XREF=gi:5174492 /UG=Hs.69954 laminin, gamma 3 /FL=gb:AF041835.1 gb:NM_006059.1 NM_006059 laminin, gamma 3 LAMC3 10319 NM_006059 /// XM_006716921 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219408_at NM_019023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019023.1 /DEF=Homo sapiens hypothetical protein (FLJ10640), mRNA. /FEA=mRNA /GEN=FLJ10640 /PROD=hypothetical protein /DB_XREF=gi:9506614 /UG=Hs.91753 hypothetical protein /FL=gb:BC000146.1 gb:NM_019023.1 NM_019023 protein arginine methyltransferase 7 PRMT7 54496 NM_001184824 /// NM_001290018 /// NM_019023 /// XM_005255988 /// XM_005255989 /// XM_005255991 /// XM_005255992 /// XM_005255993 /// XM_006721196 /// XM_006721197 /// XM_006721198 /// XM_006721199 /// XR_243413 0000387 // spliceosomal snRNP assembly // inferred from mutant phenotype /// 0006349 // regulation of gene expression by genetic imprinting // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006479 // protein methylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0018216 // peptidyl-arginine methylation // inferred from direct assay /// 0018216 // peptidyl-arginine methylation // inferred from mutant phenotype /// 0019918 // peptidyl-arginine methylation, to symmetrical-dimethyl arginine // inferred from direct assay /// 0019918 // peptidyl-arginine methylation, to symmetrical-dimethyl arginine // inferred from mutant phenotype /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0034969 // histone arginine methylation // inferred from sequence or structural similarity /// 0035247 // peptidyl-arginine omega-N-methylation // inferred from direct assay /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity /// 0043393 // regulation of protein binding // inferred by curator /// 0043985 // histone H4-R3 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // inferred from direct assay /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from direct assay /// 0016277 // [myelin basic protein]-arginine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0035241 // protein-arginine omega-N monomethyltransferase activity // inferred from direct assay /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0035243 // protein-arginine omega-N symmetric methyltransferase activity // inferred from direct assay /// 0035243 // protein-arginine omega-N symmetric methyltransferase activity // inferred from mutant phenotype /// 0042393 // histone binding // inferred by curator /// 0043021 // ribonucleoprotein complex binding // inferred from physical interaction /// 0044020 // histone methyltransferase activity (H4-R3 specific) // inferred from sequence or structural similarity 219409_at NM_024700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024700.1 /DEF=Homo sapiens hypothetical protein FLJ12553 (FLJ12553), mRNA. /FEA=mRNA /GEN=FLJ12553 /PROD=hypothetical protein FLJ12553 /DB_XREF=gi:13375986 /UG=Hs.99601 hypothetical protein FLJ12553 /FL=gb:NM_024700.1 NM_024700 Smad nuclear interacting protein 1 SNIP1 79753 NM_024700 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219410_at NM_018004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018004.1 /DEF=Homo sapiens hypothetical protein FLJ10134 (FLJ10134), mRNA. /FEA=mRNA /GEN=FLJ10134 /PROD=hypothetical protein FLJ10134 /DB_XREF=gi:8922242 /UG=Hs.104800 hypothetical protein FLJ10134 /FL=gb:NM_018004.1 NM_018004 transmembrane protein 45A TMEM45A 55076 NM_018004 /// XM_005247568 /// XM_005247569 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219411_at NM_024712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024712.1 /DEF=Homo sapiens hypothetical protein FLJ13824 (FLJ13824), mRNA. /FEA=mRNA /GEN=FLJ13824 /PROD=hypothetical protein FLJ13824 /DB_XREF=gi:13376010 /UG=Hs.105861 hypothetical protein FLJ13824 /FL=gb:NM_024712.1 NM_024712 engulfment and cell motility 3 ELMO3 79767 NM_024712 0006909 // phagocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 219412_at NM_022337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022337.1 /DEF=Homo sapiens RAB38, member RAS oncogene family (RAB38), mRNA. /FEA=mRNA /GEN=RAB38 /PROD=RAB38, member RAS oncogene family /DB_XREF=gi:11641236 /UG=Hs.108923 RAB38, member RAS oncogene family /FL=gb:AF235022.1 gb:NM_022337.1 NM_022337 RAB38, member RAS oncogene family RAB38 23682 NM_022337 /// XM_005273860 /// XM_006718807 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006996 // organelle organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0060155 // platelet dense granule organization // inferred from electronic annotation /// 0072657 // protein localization to membrane // inferred from mutant phenotype /// 0090383 // phagosome acidification // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031905 // early endosome lumen // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from physical interaction /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay /// 0035650 // AP-1 adaptor complex binding // inferred from physical interaction /// 0035651 // AP-3 adaptor complex binding // inferred from physical interaction 219413_at NM_024722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024722.1 /DEF=Homo sapiens hypothetical protein FLJ13322 (FLJ13322), mRNA. /FEA=mRNA /GEN=FLJ13322 /PROD=hypothetical protein FLJ13322 /DB_XREF=gi:13376028 /UG=Hs.110298 hypothetical protein FLJ13322 /FL=gb:NM_024722.1 NM_024722 acyl-CoA binding domain containing 4 ACBD4 79777 NM_001135704 /// NM_001135705 /// NM_001135706 /// NM_001135707 /// NM_024722 /// XM_005257673 /// XM_005257674 /// XM_005257677 /// XM_006722085 /// XM_006722086 /// XM_006722087 /// XM_006722088 /// XM_006722089 /// XM_006722090 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 219414_at NM_022131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022131.1 /DEF=Homo sapiens calsyntenin-2 (CS2), mRNA. /FEA=mRNA /GEN=CS2 /PROD=calsyntenin-2 /DB_XREF=gi:11545860 /UG=Hs.12079 calsyntenin-2 /FL=gb:NM_022131.1 NM_022131 calsyntenin 2 CLSTN2 64084 NM_022131 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 219415_at NM_020659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020659.1 /DEF=Homo sapiens tweety (Drosophila) homolog 1 (TTYH1), mRNA. /FEA=mRNA /GEN=TTYH1 /PROD=tweety (Drosophila) homolog 1 /DB_XREF=gi:10257436 /UG=Hs.12828 tweety (Drosophila) homolog 1 /FL=gb:NM_020659.1 gb:AF177909.1 NM_020659 tweety family member 1 TTYH1 57348 NM_001005367 /// NM_001201461 /// NM_020659 /// XM_006723296 /// XM_006726274 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0006826 // iron ion transport // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0034755 // iron ion transmembrane transport // non-traceable author statement /// 0044070 // regulation of anion transport // inferred from direct assay /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030868 // smooth endoplasmic reticulum membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032433 // filopodium tip // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005254 // chloride channel activity // inferred from electronic annotation /// 0005381 // iron ion transmembrane transporter activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0072320 // volume-sensitive chloride channel activity // inferred from direct assay 219416_at NM_016240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016240.1 /DEF=Homo sapiens CSR1 protein (CSR1), mRNA. /FEA=mRNA /GEN=CSR1 /PROD=CSR1 protein /DB_XREF=gi:7705335 /UG=Hs.128856 CSR1 protein /FL=gb:AB007829.1 gb:NM_016240.1 NM_016240 scavenger receptor class A, member 3 SCARA3 51435 NM_016240 /// NM_182826 /// XM_005273527 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0009650 // UV protection // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005044 // scavenger receptor activity // traceable author statement 219417_s_at NM_017622 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017622.1 /DEF=Homo sapiens hypothetical protein FLJ20014 (FLJ20014), mRNA. /FEA=mRNA /GEN=FLJ20014 /PROD=hypothetical protein FLJ20014 /DB_XREF=gi:8923020 /UG=Hs.129563 hypothetical protein FLJ20014 /FL=gb:NM_017622.1 NM_017622 chromosome 17 open reading frame 59 C17orf59 54785 NM_017622 0005515 // protein binding // inferred from electronic annotation 219418_at NM_024782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024782.1 /DEF=Homo sapiens hypothetical protein FLJ12610 (FLJ12610), mRNA. /FEA=mRNA /GEN=FLJ12610 /PROD=hypothetical protein FLJ12610 /DB_XREF=gi:13376141 /UG=Hs.146139 hypothetical protein FLJ12610 /FL=gb:NM_024782.1 NM_024782 nonhomologous end-joining factor 1 /// solute carrier family 23, member 3 NHEJ1 /// SLC23A3 79840 /// 151295 NM_001144889 /// NM_001144890 /// NM_024782 /// NM_144712 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0030183 // B cell differentiation // inferred from mutant phenotype /// 0030217 // T cell differentiation // inferred from mutant phenotype /// 0051351 // positive regulation of ligase activity // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219419_at NM_024805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024805.1 /DEF=Homo sapiens hypothetical protein FLJ21172 (FLJ21172), mRNA. /FEA=mRNA /GEN=FLJ21172 /PROD=hypothetical protein FLJ21172 /DB_XREF=gi:13376184 /UG=Hs.164207 hypothetical protein FLJ21172 /FL=gb:NM_024805.1 NM_024805 ribosome binding factor A (putative) RBFA 79863 NM_001171967 /// NM_024805 0006364 // rRNA processing // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 219420_s_at NM_023077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023077.1 /DEF=Homo sapiens hypothetical protein FLJ12439 (FLJ12439), mRNA. /FEA=mRNA /GEN=FLJ12439 /PROD=hypothetical protein FLJ12439 /DB_XREF=gi:12751490 /UG=Hs.164371 hypothetical protein FLJ12439 /FL=gb:NM_023077.1 NM_023077 cytochrome c oxidase assembly factor 7 (putative) COA7 65260 NM_023077 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 219421_at NM_012382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012382.1 /DEF=Homo sapiens osmosis responsive factor (OSRF), mRNA. /FEA=mRNA /GEN=OSRF /PROD=osmosis responsive factor /DB_XREF=gi:7110678 /UG=Hs.170096 osmosis responsive factor /FL=gb:AF130073.1 gb:AF023244.1 gb:NM_012382.1 NM_012382 tetratricopeptide repeat domain 33 TTC33 23548 NM_012382 /// XM_005248276 /// XM_006714462 0005515 // protein binding // inferred from electronic annotation 219422_at U72763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U72763.1 /DEF=Human death receptor 3 (DR3) mRNA, complete cds. /FEA=CDS /GEN=DR3 /PROD=death receptor 3 /DB_XREF=gi:1669511 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) /FL=gb:U72763.1 gb:U74611.1 gb:U78029.1 gb:U94501.1 gb:U94502.1 gb:NM_003790.1 U72763 espin ESPN 83715 NM_031475 /// XM_005263501 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030046 // parallel actin filament bundle assembly // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051494 // negative regulation of cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005903 // brush border // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0032420 // stereocilium // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0032426 // stereocilium bundle tip // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity 219423_x_at NM_003790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003790.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) (TNFRSF12), mRNA. /FEA=mRNA /GEN=TNFRSF12 /PROD=tumor necrosis factor receptor superfamily,member 12 /DB_XREF=gi:4507568 /UG=Hs.180338 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) /FL=gb:U72763.1 gb:U74611.1 gb:U78029.1 gb:U94501.1 gb:U94502.1 gb:NM_003790.1 NM_003790 tumor necrosis factor receptor superfamily, member 25 TNFRSF25 8718 NM_001039664 /// NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148974 0006915 // apoptotic process // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // non-traceable author statement /// 0005031 // tumor necrosis factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219424_at NM_005755 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005755.1 /DEF=Homo sapiens Epstein-Barr virus induced gene 3 (EBI3), mRNA. /FEA=mRNA /GEN=EBI3 /PROD=Epstein-Barr virus induced gene 3 /DB_XREF=gi:5031678 /UG=Hs.185705 Epstein-Barr virus induced gene 3 /FL=gb:NM_005755.1 gb:L08187.1 NM_005755 Epstein-Barr virus induced 3 EBI3 10148 NM_005755 /// XM_006722605 0006959 // humoral immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from physical interaction /// 0042088 // T-helper 1 type immune response // traceable author statement /// 0045078 // positive regulation of interferon-gamma biosynthetic process // traceable author statement /// 0046641 // positive regulation of alpha-beta T cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from physical interaction /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0045523 // interleukin-27 receptor binding // inferred from electronic annotation 219425_at NM_014351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014351.1 /DEF=Homo sapiens sulfotransferase-related protein (SULTX3), mRNA. /FEA=mRNA /GEN=SULTX3 /PROD=sulfotransferase-related protein /DB_XREF=gi:7657632 /UG=Hs.189810 sulfortranferase family 4A, member 1 /FL=gb:AF115311.1 gb:AF188698.1 gb:NM_014351.1 gb:AF251263.1 NM_014351 sulfotransferase family 4A, member 1 SULT4A1 25830 NM_014351 /// NM_176874 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006790 // sulfur compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 219426_at NM_024852 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024852.1 /DEF=Homo sapiens hypothetical protein FLJ12765 (FLJ12765), mRNA. /FEA=mRNA /GEN=FLJ12765 /PROD=hypothetical protein FLJ12765 /DB_XREF=gi:13376274 /UG=Hs.189829 hypothetical protein FLJ12765 /FL=gb:NM_024852.1 NM_024852 argonaute RISC catalytic component 3 AGO3 192669 NM_024852 /// NM_177422 /// XM_005270575 /// XM_005270576 /// XM_006710404 0006402 // mRNA catabolic process // inferred from direct assay /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0072091 // regulation of stem cell proliferation // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0035068 // micro-ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035198 // miRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219427_at NM_024582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024582.1 /DEF=Homo sapiens hypothetical protein FLJ23056 (FLJ23056), mRNA. /FEA=mRNA /GEN=FLJ23056 /PROD=hypothetical protein FLJ23056 /DB_XREF=gi:13375763 /UG=Hs.20914 hypothetical protein FLJ23056 /FL=gb:NM_024582.1 NM_024582 FAT atypical cadherin 4 FAT4 79633 NM_001291285 /// NM_001291303 /// NM_024582 /// XM_005263210 /// XM_006714304 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0035329 // hippo signaling // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219428_s_at BF057649 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057649 /FEA=EST /DB_XREF=gi:10811545 /DB_XREF=est:7k51d07.x1 /CLONE=IMAGE:3479076 /UG=Hs.241205 24 kDa intrinsic membrane protein /FL=gb:AL136648.1 gb:AF072864.1 gb:NM_007238.1 BF057649 peroxisomal membrane protein 4, 24kDa PXMP4 11264 NM_007238 /// NM_183397 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219429_at NM_024306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024306.1 /DEF=Homo sapiens fatty acid hydroxylase (FAAH), mRNA. /FEA=mRNA /GEN=FAAH /PROD=fatty acid hydroxylase /DB_XREF=gi:13236537 /UG=Hs.249163 fatty acid hydroxylase /FL=gb:BC002679.1 gb:NM_024306.1 gb:BC004263.1 NM_024306 fatty acid 2-hydroxylase FA2H 79152 NM_024306 0001949 // sebaceous gland cell differentiation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030258 // lipid modification // inferred from electronic annotation /// 0032286 // central nervous system myelin maintenance // inferred from electronic annotation /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042634 // regulation of hair cycle // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0080132 // fatty acid alpha-hydroxylase activity // inferred from electronic annotation 219430_at NM_020155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020155.1 /DEF=Homo sapiens chromosome 11 hypothetical protein ORF4 (LOC56834), mRNA. /FEA=mRNA /GEN=LOC56834 /PROD=chromosome 11 hypothetical protein ORF4 /DB_XREF=gi:9910343 /UG=Hs.25274 chromosome 11 hypothetical protein ORF4 /FL=gb:NM_020155.1 NM_020155 G protein-coupled receptor 137 GPR137 56834 NM_001170726 /// NM_001170880 /// NM_001170881 /// NM_001177358 /// NM_020155 /// XM_005274100 /// XM_005274101 /// XM_005274102 /// XM_005274104 /// XM_006718636 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219431_at NM_024605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024605.1 /DEF=Homo sapiens hypothetical protein FLJ20896 (FLJ20896), mRNA. /FEA=mRNA /GEN=FLJ20896 /PROD=hypothetical protein FLJ20896 /DB_XREF=gi:13375810 /UG=Hs.26756 hypothetical protein FLJ20896 /FL=gb:NM_024605.1 NM_024605 Rho GTPase activating protein 10 ARHGAP10 79658 NM_024605 /// XM_005263214 /// XM_005263215 /// XM_005263216 /// XM_005263217 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 219432_at NM_014556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014556.1 /DEF=Homo sapiens Ellis van Creveld syndrome (EVC), mRNA. /FEA=mRNA /GEN=EVC /PROD=Ellis van Creveld syndrome protein /DB_XREF=gi:7657072 /UG=Hs.274446 Ellis van Creveld syndrome /FL=gb:AF216184.1 gb:AF239742.1 gb:NM_014556.1 NM_014556 Ellis van Creveld syndrome EVC 2121 NM_014556 /// NM_153717 /// XM_005247952 /// XM_006713865 /// XM_006713866 /// XM_006713867 /// XR_427471 /// XR_427472 /// XR_427473 /// XR_427474 /// XR_427475 /// XR_427476 /// XR_427477 0001501 // skeletal system development // traceable author statement /// 0003416 // endochondral bone growth // inferred from sequence or structural similarity /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 219433_at NM_017745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017745.1 /DEF=Homo sapiens hypothetical protein FLJ20285 (FLJ20285), mRNA. /FEA=mRNA /GEN=FLJ20285 /PROD=hypothetical protein FLJ20285 /DB_XREF=gi:8923266 /UG=Hs.278732 hypothetical protein FLJ20285 /FL=gb:NM_017745.1 NM_017745 BCL6 corepressor BCOR 54880 NM_001123383 /// NM_001123384 /// NM_001123385 /// NM_001130139 /// NM_017745 /// NM_020926 /// XM_005272616 /// XM_005272617 /// XM_005272618 /// XM_005272619 /// XM_005272620 /// XM_006724536 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000415 // negative regulation of histone H3-K36 methylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from mutant phenotype /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0042476 // odontogenesis // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0065001 // specification of axis polarity // inferred from mutant phenotype /// 0070171 // negative regulation of tooth mineralization // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 219434_at NM_018643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018643.1 /DEF=Homo sapiens triggering receptor expressed on myeloid cells 1 (TREM1), mRNA. /FEA=mRNA /GEN=TREM1 /PROD=triggering receptor expressed on myeloid cells1 /DB_XREF=gi:8924261 /UG=Hs.283022 triggering receptor expressed on myeloid cells 1 /FL=gb:AF196329.1 gb:NM_018643.1 gb:AF287008.1 NM_018643 triggering receptor expressed on myeloid cells 1 TREM1 54210 NM_001242589 /// NM_001242590 /// NM_018643 /// XM_006715117 0006959 // humoral immune response // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0097110 // scaffold protein binding // inferred from physical interaction 219435_at NM_025099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025099.1 /DEF=Homo sapiens hypothetical protein FLJ22170 (FLJ22170), mRNA. /FEA=mRNA /GEN=FLJ22170 /PROD=hypothetical protein FLJ22170 /DB_XREF=gi:13376664 /UG=Hs.288573 hypothetical protein FLJ22170 /FL=gb:NM_025099.1 NM_025099 CTS telomere maintenance complex component 1 CTC1 80169 NM_025099 /// NR_046431 /// XM_006721577 /// XM_006721578 /// XM_006721579 /// XR_429823 /// XR_429824 /// XR_429825 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0010833 // telomere maintenance via telomere lengthening // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048539 // bone marrow development // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from electronic annotation /// 0090399 // replicative senescence // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0070188 // Stn1-Ten1 complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 219436_s_at NM_016242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016242.1 /DEF=Homo sapiens endomucin-2 (LOC51705), mRNA. /FEA=mRNA /GEN=LOC51705 /PROD=endomucin-2 /DB_XREF=gi:7706452 /UG=Hs.41135 endomucin-2 /FL=gb:AB034695.1 gb:NM_016242.1 gb:AF205940.1 NM_016242 endomucin EMCN 51705 NM_001159694 /// NM_016242 /// XM_005263059 /// XM_005263061 0001525 // angiogenesis // inferred from expression pattern /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030246 // carbohydrate binding // inferred from direct assay 219437_s_at NM_013275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013275.1 /DEF=Homo sapiens nasopharyngeal carcinoma susceptibility protein (LZ16), mRNA. /FEA=mRNA /GEN=LZ16 /PROD=nasopharyngeal carcinoma susceptibility protein /DB_XREF=gi:7019448 /UG=Hs.42390 nasopharyngeal carcinoma susceptibility protein /FL=gb:AF121775.1 gb:NM_013275.1 NM_013275 ankyrin repeat domain 11 ANKRD11 29123 NM_001256182 /// NM_001256183 /// NM_013275 /// NR_045839 /// XM_006721181 /// XM_006721182 /// XM_006721183 /// XM_006721184 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219438_at NM_024522 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024522.1 /DEF=Homo sapiens hypothetical protein FLJ12650 (FLJ12650), mRNA. /FEA=mRNA /GEN=FLJ12650 /PROD=hypothetical protein FLJ12650 /DB_XREF=gi:13375663 /UG=Hs.4243 hypothetical protein FLJ12650 /FL=gb:NM_024522.1 NM_024522 Na+/K+ transporting ATPase interacting 1 NKAIN1 79570 NM_024522 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219439_at NM_020156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020156.1 /DEF=Homo sapiens core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase (C1GALT1), mRNA. /FEA=mRNA /GEN=C1GALT1 /PROD=core1UDP-galactose:N-acetylgalactosamine-alpha-R beta1,3-galactosyltransferase /DB_XREF=gi:9910143 /UG=Hs.46744 core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase /FL=gb:AF155582.1 gb:NM_020156.1 NM_020156 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 C1GALT1 56913 NM_020156 /// XM_005249812 /// XM_005249813 /// XM_006715759 0001525 // angiogenesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from mutant phenotype /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0016263 // glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219440_at NM_021785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021785.2 /DEF=Homo sapiens retinoic acid induced 2 (RAI2), mRNA. /FEA=mRNA /GEN=RAI2 /PROD=retinoic acid induced 2 /DB_XREF=gi:12056469 /UG=Hs.49597 retinoic acid induced 2 /FL=gb:NM_021785.2 NM_021785 retinoic acid induced 2 RAI2 10742 NM_001172732 /// NM_001172739 /// NM_001172743 /// NM_021785 /// NR_033348 /// NR_033349 /// XM_006724459 /// XM_006724460 0009790 // embryo development // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 219441_s_at NM_024652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024652.1 /DEF=Homo sapiens hypothetical protein FLJ23119 (FLJ23119), mRNA. /FEA=mRNA /GEN=FLJ23119 /PROD=hypothetical protein FLJ23119 /DB_XREF=gi:13375898 /UG=Hs.57760 hypothetical protein FLJ23119 /FL=gb:NM_024652.1 NM_024652 leucine-rich repeat kinase 1 LRRK1 79705 NM_024652 /// XM_005254979 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219442_at NM_024048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024048.1 /DEF=Homo sapiens hypothetical protein MGC3020 (MGC3020), mRNA. /FEA=mRNA /GEN=MGC3020 /PROD=hypothetical protein MGC3020 /DB_XREF=gi:13129011 /UG=Hs.69428 hypothetical protein MGC3020 /FL=gb:BC000552.1 gb:NM_024048.1 NM_024048 clustered mitochondria (cluA/CLU1) homolog pseudogene 3 CLUHP3 100132341 NM_024048 /// NR_024034 219443_at NM_017714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017714.1 /DEF=Homo sapiens hypothetical protein FLJ20212 (FLJ20212), mRNA. /FEA=mRNA /GEN=FLJ20212 /PROD=hypothetical protein FLJ20212 /DB_XREF=gi:8923201 /UG=Hs.88367 hypothetical protein FLJ20212 /FL=gb:NM_017714.1 NM_017714 taspase, threonine aspartase, 1 TASP1 55617 NM_017714 /// XM_006723589 /// XM_006723590 /// XR_430268 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0004298 // threonine-type endopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219444_at NM_021946 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021946.1 /DEF=Homo sapiens hypothetical protein FLJ11362 (FLJ11362), mRNA. /FEA=mRNA /GEN=FLJ11362 /PROD=hypothetical protein FLJ11362 /DB_XREF=gi:11345489 /UG=Hs.8929 hypothetical protein FLJ11362 /FL=gb:NM_021946.1 NM_021946 BCL6 corepressor-like 1 BCORL1 63035 NM_001184772 /// NM_021946 /// XM_005262452 /// XM_005262453 /// XM_005262454 /// XM_005262455 /// XM_005262456 /// XM_006724776 /// XM_006724777 /// XM_006724778 /// XM_006724779 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219445_at NM_015711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015711.1 /DEF=Homo sapiens glioma tumor suppressor candidate region gene 1 (GLTSCR1), mRNA. /FEA=mRNA /GEN=GLTSCR1 /PROD=glioma tumor suppressor candidate region gene 1 /DB_XREF=gi:7657127 /UG=Hs.97244 glioma tumor suppressor candidate region gene 1 /FL=gb:AF182077.1 gb:NM_015711.1 NM_015711 glioma tumor suppressor candidate region gene 1 GLTSCR1 29998 NM_015711 /// XM_005258833 /// XM_006723180 0005515 // protein binding // inferred from physical interaction 219446_at NM_018157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018157.1 /DEF=Homo sapiens hypothetical protein FLJ10620 (FLJ10620), mRNA. /FEA=mRNA /GEN=FLJ10620 /PROD=hypothetical protein FLJ10620 /DB_XREF=gi:8922554 /UG=Hs.99445 hypothetical protein FLJ10620 /FL=gb:NM_018157.1 NM_018157 RIC8 guanine nucleotide exchange factor B RIC8B 55188 NM_018157 /// XM_005268998 /// XM_005268999 /// XR_245940 /// XR_245942 /// XR_245943 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 219447_s_at NM_015945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015945.1 /DEF=Homo sapiens CGI-15 protein (LOC51006), mRNA. /FEA=mRNA /GEN=LOC51006 /PROD=CGI-15 protein /DB_XREF=gi:7705597 /UG=Hs.10117 CGI-15 protein /FL=gb:AF132949.1 gb:NM_015945.1 NM_015945 solute carrier family 35 (GDP-fucose transporter), member C2 SLC35C2 51006 NM_001281457 /// NM_001281458 /// NM_001281459 /// NM_001281460 /// NM_015945 /// NM_173073 /// NM_173179 /// XM_005260414 /// XM_006723801 0006810 // transport // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036066 // protein O-linked fucosylation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219448_at BC002748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002748.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20533, clone MGC:3448, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20533 /DB_XREF=gi:12803814 /UG=Hs.106650 hypothetical protein FLJ20533 /FL=gb:BC002748.1 gb:NM_017866.1 BC002748 transmembrane protein 70 TMEM70 54968 NM_001040613 /// NM_017866 /// NR_033334 0033615 // mitochondrial proton-transporting ATP synthase complex assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay 219449_s_at NM_017866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017866.1 /DEF=Homo sapiens hypothetical protein FLJ20533 (FLJ20533), mRNA. /FEA=mRNA /GEN=FLJ20533 /PROD=hypothetical protein FLJ20533 /DB_XREF=gi:8923499 /UG=Hs.106650 hypothetical protein FLJ20533 /FL=gb:BC002748.1 gb:NM_017866.1 NM_017866 transmembrane protein 70 TMEM70 54968 NM_001040613 /// NM_017866 /// NR_033334 0033615 // mitochondrial proton-transporting ATP synthase complex assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from direct assay 219450_at NM_018302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018302.1 /DEF=Homo sapiens hypothetical protein FLJ11017 (FLJ11017), mRNA. /FEA=mRNA /GEN=FLJ11017 /PROD=hypothetical protein FLJ11017 /DB_XREF=gi:8922827 /UG=Hs.107527 hypothetical protein FLJ11017 /FL=gb:NM_018302.1 NM_018302 chromosome 4 open reading frame 19 C4orf19 55286 NM_001104629 /// NM_018302 219451_at NM_016064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016064.1 /DEF=Homo sapiens CGI-131 protein (LOC51648), mRNA. /FEA=mRNA /GEN=LOC51648 /PROD=CGI-131 protein /DB_XREF=gi:7706344 /UG=Hs.109733 CGI-131 protein /FL=gb:AF151889.1 gb:NM_016064.1 NM_016064 methionine sulfoxide reductase B2 MSRB2 22921 NM_012228 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030091 // protein repair // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0033743 // peptide-methionine (R)-S-oxide reductase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 219452_at NM_022355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022355.1 /DEF=Homo sapiens putative dipeptidase (LOC64174), mRNA. /FEA=mRNA /GEN=LOC64174 /PROD=putative dipeptidase /DB_XREF=gi:11641268 /UG=Hs.115537 putative dipeptidase /FL=gb:NM_022355.1 NM_022355 dipeptidase 2 DPEP2 64174 NM_022355 /// XM_005256085 /// XM_005256086 /// XM_005256087 /// XM_005256090 /// XM_005256091 /// XM_006721244 /// XR_243420 0006508 // proteolysis // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008238 // exopeptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219453_at NM_024731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024731.1 /DEF=Homo sapiens hypothetical protein FLJ12543 (FLJ12543), mRNA. /FEA=mRNA /GEN=FLJ12543 /PROD=hypothetical protein FLJ12543 /DB_XREF=gi:13376047 /UG=Hs.116017 hypothetical protein FLJ12543 /FL=gb:NM_024731.1 NM_024731 kelch-like family member 36 KLHL36 79786 NM_024731 /// XM_005256149 /// XR_243425 0016567 // protein ubiquitination // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219454_at NM_015507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015507.2 /DEF=Homo sapiens EGF-like-domain, multiple 6 (EGFL6), mRNA. /FEA=mRNA /GEN=EGFL6 /PROD=epidermal growth factor-like protein 6precursor /DB_XREF=gi:13124887 /UG=Hs.12844 EGF-like-domain, multiple 6 /FL=gb:NM_015507.2 gb:AF186084.1 NM_015507 EGF-like-domain, multiple 6 EGFL6 25975 NM_001167890 /// NM_015507 0007049 // cell cycle // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219455_at NM_024788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024788.1 /DEF=Homo sapiens hypothetical protein FLJ21062 (FLJ21062), mRNA. /FEA=mRNA /GEN=FLJ21062 /PROD=hypothetical protein FLJ21062 /DB_XREF=gi:13376153 /UG=Hs.151258 hypothetical protein FLJ21062 /FL=gb:NM_024788.1 NM_024788 chromosome 7 open reading frame 63 C7orf63 79846 NM_001039706 /// NM_001160138 /// NM_024788 /// XM_005250596 /// XM_005250597 /// XM_005250598 /// XM_005250599 /// XM_005250600 /// XM_006716129 /// XM_006716130 /// XM_006716131 /// XR_242264 0005488 // binding // inferred from electronic annotation 219456_s_at AW027923 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW027923 /FEA=EST /DB_XREF=gi:5886679 /DB_XREF=est:wv25a02.x1 /CLONE=IMAGE:2530538 /UG=Hs.180040 hypothetical protein FLJ22439 /FL=gb:NM_024832.1 AW027923 Ras and Rab interactor 3 RIN3 79890 NM_024832 0006897 // endocytosis // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0017137 // Rab GTPase binding // inferred from direct assay 219457_s_at NM_024832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024832.1 /DEF=Homo sapiens hypothetical protein FLJ22439 (FLJ22439), mRNA. /FEA=mRNA /GEN=FLJ22439 /PROD=hypothetical protein FLJ22439 /DB_XREF=gi:13376237 /UG=Hs.180040 hypothetical protein FLJ22439 /FL=gb:NM_024832.1 NM_024832 Ras and Rab interactor 3 RIN3 79890 NM_024832 0006897 // endocytosis // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0017137 // Rab GTPase binding // inferred from direct assay 219458_s_at NM_022072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022072.1 /DEF=Homo sapiens hypothetical protein FLJ22609 (FLJ22609), mRNA. /FEA=mRNA /GEN=FLJ22609 /PROD=hypothetical protein FLJ22609 /DB_XREF=gi:11545784 /UG=Hs.18740 hypothetical protein FLJ22609 /FL=gb:NM_022072.1 NM_022072 NOP2/Sun domain family, member 3 NSUN3 63899 NM_022072 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219459_at NM_018082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018082.1 /DEF=Homo sapiens hypothetical protein FLJ10388 (FLJ10388), mRNA. /FEA=mRNA /GEN=FLJ10388 /PROD=hypothetical protein FLJ10388 /DB_XREF=gi:8922398 /UG=Hs.197642 hypothetical protein FLJ10388 /FL=gb:NM_018082.1 NM_018082 polymerase (RNA) III (DNA directed) polypeptide B POLR3B 55703 NM_001160708 /// NM_018082 /// XM_006719498 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005666 // DNA-directed RNA polymerase III complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032549 // ribonucleoside binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219460_s_at NM_017849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017849.1 /DEF=Homo sapiens hypothetical protein FLJ20507 (FLJ20507), mRNA. /FEA=mRNA /GEN=FLJ20507 /PROD=hypothetical protein FLJ20507 /DB_XREF=gi:8923465 /UG=Hs.202955 hypothetical protein FLJ20507 /FL=gb:NM_017849.1 NM_017849 transmembrane protein 127 TMEM127 55654 NM_001193304 /// NM_017849 /// NM_032218 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219461_at AJ236915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ236915.1 /DEF=Homo sapiens mRNA for pak5 protein. /FEA=mRNA /GEN=pak5 /PROD=pak5 protein /DB_XREF=gi:11691854 /UG=Hs.21420 p21-activated protein kinase 6 /FL=gb:AF276893.1 gb:NM_020168.1 AJ236915 p21 protein (Cdc42/Rac)-activated kinase 6 PAK6 56924 NM_001128628 /// NM_001128629 /// NM_001276717 /// NM_001276718 /// NM_020168 0000278 // mitotic cell cycle // not recorded /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219462_at NM_024587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024587.1 /DEF=Homo sapiens hypothetical protein FLJ22353 (FLJ22353), mRNA. /FEA=mRNA /GEN=FLJ22353 /PROD=hypothetical protein FLJ22353 /DB_XREF=gi:13375773 /UG=Hs.22157 hypothetical protein FLJ22353 /FL=gb:NM_024587.1 NM_024587 transmembrane protein 53 TMEM53 79639 NM_024587 /// XM_005271194 /// XM_005271195 /// XM_005271196 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219463_at NM_012261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012261.1 /DEF=Homo sapiens similar to S68401 (cattle) glucose induced gene (HS1119D91), mRNA. /FEA=mRNA /GEN=HS1119D91 /PROD=similar to S68401 (cattle) glucose induced gene /DB_XREF=gi:7110632 /UG=Hs.22920 similar to S68401 (cattle) glucose induced gene /FL=gb:NM_012261.1 NM_012261 lysosomal-associated membrane protein family, member 5 LAMP5 24141 NM_001199897 /// NM_012261 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0032584 // growth cone membrane // inferred from sequence or structural similarity /// 0032590 // dendrite membrane // inferred from sequence or structural similarity /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity 219464_at NM_012113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012113.1 /DEF=Homo sapiens carbonic anhydrase XIV (CA14), mRNA. /FEA=mRNA /GEN=CA14 /PROD=carbonic anhydrase XIV precursor /DB_XREF=gi:6912283 /UG=Hs.235168 carbonic anhydrase XIV /FL=gb:AB025904.1 gb:NM_012113.1 NM_012113 carbonic anhydrase XIV CA14 23632 NM_012113 /// XM_005245059 /// XM_005245060 /// XM_006711259 /// XM_006711260 /// XM_006711261 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219465_at NM_001643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001643.1 /DEF=Homo sapiens apolipoprotein A-II (APOA2), mRNA. /FEA=mRNA /GEN=APOA2 /PROD=apolipoprotein A-II precursor /DB_XREF=gi:4502148 /UG=Hs.237658 apolipoprotein A-II /FL=gb:BC005282.1 gb:M29882.1 gb:NM_001643.1 NM_001643 apolipoprotein A-II APOA2 336 NM_001643 0001523 // retinoid metabolic process // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0006457 // protein folding // inferred from direct assay /// 0006641 // triglyceride metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from direct assay /// 0032375 // negative regulation of cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034370 // triglyceride-rich lipoprotein particle remodeling // inferred from direct assay /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from direct assay /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0046340 // diacylglycerol catabolic process // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0050996 // positive regulation of lipid catabolic process // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060192 // negative regulation of lipase activity // inferred from direct assay /// 0060621 // negative regulation of cholesterol import // inferred from direct assay /// 0060695 // negative regulation of cholesterol transporter activity // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034190 // apolipoprotein receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070653 // high-density lipoprotein particle receptor binding // inferred from physical interaction 219466_s_at NM_001643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001643.1 /DEF=Homo sapiens apolipoprotein A-II (APOA2), mRNA. /FEA=mRNA /GEN=APOA2 /PROD=apolipoprotein A-II precursor /DB_XREF=gi:4502148 /UG=Hs.237658 apolipoprotein A-II /FL=gb:BC005282.1 gb:M29882.1 gb:NM_001643.1 NM_001643 apolipoprotein A-II APOA2 336 NM_001643 0001523 // retinoid metabolic process // traceable author statement /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002740 // negative regulation of cytokine secretion involved in immune response // inferred from direct assay /// 0006457 // protein folding // inferred from direct assay /// 0006641 // triglyceride metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0009749 // response to glucose // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010903 // negative regulation of very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030300 // regulation of intestinal cholesterol absorption // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from direct assay /// 0032375 // negative regulation of cholesterol transport // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034370 // triglyceride-rich lipoprotein particle remodeling // inferred from direct assay /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from direct assay /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0046340 // diacylglycerol catabolic process // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0050996 // positive regulation of lipid catabolic process // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060192 // negative regulation of lipase activity // inferred from direct assay /// 0060621 // negative regulation of cholesterol import // inferred from direct assay /// 0060695 // negative regulation of cholesterol transporter activity // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034190 // apolipoprotein receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070653 // high-density lipoprotein particle receptor binding // inferred from physical interaction 219467_at NM_017676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017676.1 /DEF=Homo sapiens hypothetical protein FLJ20125 (FLJ20125), mRNA. /FEA=mRNA /GEN=FLJ20125 /PROD=hypothetical protein FLJ20125 /DB_XREF=gi:8923123 /UG=Hs.24088 hypothetical protein FLJ20125 /FL=gb:NM_017676.1 NM_017676 gypsy retrotransposon integrase 1 GIN1 54826 NM_017676 /// XM_005272028 /// XM_005272029 /// XM_005272030 /// XM_006714655 0015074 // DNA integration // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 219468_s_at NM_017949 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017949.1 /DEF=Homo sapiens hypothetical protein FLJ20739 (FLJ20739), mRNA. /FEA=mRNA /GEN=FLJ20739 /PROD=hypothetical protein FLJ20739 /DB_XREF=gi:8923664 /UG=Hs.272824 hypothetical protein FLJ20739 /FL=gb:NM_017949.1 NM_017949 CUE domain containing 1 CUEDC1 404093 NM_001271875 /// NM_001292025 /// NR_073495 /// XM_006721900 /// XM_006721901 /// XM_006721902 /// XR_429891 0005515 // protein binding // inferred from electronic annotation 219469_at NM_024606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024606.1 /DEF=Homo sapiens hypothetical protein FLJ11756 (FLJ11756), mRNA. /FEA=mRNA /GEN=FLJ11756 /PROD=hypothetical protein FLJ11756 /DB_XREF=gi:13375812 /UG=Hs.27497 hypothetical protein FLJ11756 /FL=gb:NM_024606.1 NM_024606 dynein, cytoplasmic 2, heavy chain 1 DYNC2H1 79659 NM_001080463 /// NM_001377 /// NM_024606 /// XM_006718903 0001539 // cilium or flagellum-dependent cell motility // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008105 // asymmetric protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // non-traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 219470_x_at NM_019084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019084.1 /DEF=Homo sapiens hypothetical protein FLJ10895 (FLJ10895), mRNA. /FEA=mRNA /GEN=FLJ10895 /PROD=hypothetical protein FLJ10895 /DB_XREF=gi:9506628 /UG=Hs.281348 hypothetical protein FLJ10895 /FL=gb:NM_019084.1 NM_019084 cyclin J CCNJ 54619 NM_001134375 /// NM_001134376 /// NM_019084 /// XM_005269921 0005634 // nucleus // inferred from electronic annotation 219471_at NM_025113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025113.1 /DEF=Homo sapiens hypothetical protein FLJ21562 (FLJ21562), mRNA. /FEA=mRNA /GEN=FLJ21562 /PROD=hypothetical protein FLJ21562 /DB_XREF=gi:13376686 /UG=Hs.288708 hypothetical protein FLJ21562 /FL=gb:NM_025113.1 NM_025113 KIAA0226-like KIAA0226L 80183 NM_001286761 /// NM_001286762 /// NM_001286763 /// NM_001286764 /// NM_001286765 /// NM_001286766 /// NM_025113 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation 219472_at NM_024322 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024322.1 /DEF=Homo sapiens hypothetical protein MGC11266 (MGC11266), mRNA. /FEA=mRNA /GEN=MGC11266 /PROD=hypothetical protein MGC11266 /DB_XREF=gi:13236564 /UG=Hs.293943 hypothetical protein MGC11266 /FL=gb:BC002870.1 gb:NM_024322.1 NM_024322 centromere protein O CENPO 79172 NM_001199803 /// NM_024322 /// XM_006712102 /// XR_244957 /// XR_244958 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034508 // centromere complex assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 219473_at NM_017686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017686.1 /DEF=Homo sapiens hypothetical protein FLJ20142 (FLJ20142), mRNA. /FEA=mRNA /GEN=FLJ20142 /PROD=hypothetical protein FLJ20142 /DB_XREF=gi:8923142 /UG=Hs.29493 hypothetical protein FLJ20142 /FL=gb:NM_017686.1 NM_017686 ganglioside induced differentiation associated protein 2 GDAP2 54834 NM_001135589 /// NM_017686 /// XM_005270959 0032526 // response to retinoic acid // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay 219474_at NM_024616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024616.1 /DEF=Homo sapiens hypothetical protein FLJ23186 (FLJ23186), mRNA. /FEA=mRNA /GEN=FLJ23186 /PROD=hypothetical protein FLJ23186 /DB_XREF=gi:13375833 /UG=Hs.30085 hypothetical protein FLJ23186 /FL=gb:NM_024616.1 NM_024616 chromosome 3 open reading frame 52 C3orf52 79669 NM_001171747 /// NM_024616 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219475_at NM_013370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013370.1 /DEF=Homo sapiens pregnancy-induced growth inhibitor (OKL38), mRNA. /FEA=mRNA /GEN=OKL38 /PROD=pregnancy-induced growth inhibitor /DB_XREF=gi:7019474 /UG=Hs.31773 pregnancy-induced growth inhibitor /FL=gb:AF191740.1 gb:NM_013370.1 NM_013370 oxidative stress induced growth inhibitor 1 OSGIN1 29948 NM_013370 /// NM_182980 /// NM_182981 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation 0008083 // growth factor activity // inferred from direct assay 219476_at NM_024115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024115.1 /DEF=Homo sapiens hypothetical protein MGC4309 (MGC4309), mRNA. /FEA=mRNA /GEN=MGC4309 /PROD=hypothetical protein MGC4309 /DB_XREF=gi:13129133 /UG=Hs.32417 hypothetical protein MGC4309 /FL=gb:BC002325.1 gb:BC001943.1 gb:NM_024115.1 NM_024115 chromosome 1 open reading frame 116 C1orf116 79098 NM_001083924 /// NM_023938 /// XM_005273259 /// XM_006711530 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 219477_s_at NM_018676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018676.1 /DEF=Homo sapiens TMTSP for transmembrane molecule with thrombospondin module (LOC55901), mRNA. /FEA=mRNA /GEN=LOC55901 /PROD=TMTSP for transmembrane molecule withthrombospondin module /DB_XREF=gi:8923893 /UG=Hs.325667 TMTSP for transmembrane molecule with thrombospondin module /FL=gb:AB044385.1 gb:NM_018676.1 NM_018676 uncharacterized LOC101930578 /// mitochondrial ribosomal protein S31 pseudogene 5 /// thrombospondin, type I, domain containing 1 LOC101930578 /// MRPS31P5 /// THSD1 55901 /// 100887750 /// 101930578 NM_018676 /// NM_199263 /// NR_002816 /// NR_051963 /// NR_051964 /// NR_051965 /// XR_250573 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation 219478_at NM_021197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021197.1 /DEF=Homo sapiens WAP four-disulfide core domain 1 (WFDC1), mRNA. /FEA=mRNA /GEN=WFDC1 /PROD=WAP four-disulfide core domain 1 /DB_XREF=gi:10864006 /UG=Hs.36688 WAP four-disulfide core domain 1 /FL=gb:AF302109.1 gb:AF169631.1 gb:NM_021197.1 NM_021197 WAP four-disulfide core domain 1 WFDC1 58189 NM_001282466 /// NM_001282467 /// NM_021197 /// XM_005256079 0001558 // regulation of cell growth // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 219479_at NM_024089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024089.1 /DEF=Homo sapiens hypothetical protein MGC5302 (MGC5302), mRNA. /FEA=mRNA /GEN=MGC5302 /PROD=hypothetical protein MGC5302 /DB_XREF=gi:13129085 /UG=Hs.44970 endoplasmic reticulum resident protein 58; hypothetical protein MGC5302 /FL=gb:BC001297.1 gb:NM_024089.1 NM_024089 KDEL (Lys-Asp-Glu-Leu) containing 1 KDELC1 79070 NM_024089 /// XM_005254074 /// XM_005254075 /// XM_005254076 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 219480_at NM_005985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005985.1 /DEF=Homo sapiens snail 1 (drosophila homolog), zinc finger protein (SNAI1), mRNA. /FEA=mRNA /GEN=SNAI1 /PROD=snail 1 (drosophila homolog), zinc fingerprotein /DB_XREF=gi:5174686 /UG=Hs.48029 snail 1 (drosophila homolog), zinc finger protein /FL=gb:AF125377.1 gb:NM_005985.1 NM_005985 snail family zinc finger 1 SNAI1 6615 NM_005985 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // traceable author statement /// 0010957 // negative regulation of vitamin D biosynthetic process // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060806 // negative regulation of cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0060972 // left/right pattern formation // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred from sequence or structural similarity /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219481_at NM_024525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024525.1 /DEF=Homo sapiens hypothetical protein FLJ22584 (FLJ22584), mRNA. /FEA=mRNA /GEN=FLJ22584 /PROD=hypothetical protein FLJ22584 /DB_XREF=gi:13375669 /UG=Hs.4947 hypothetical protein FLJ22584 /FL=gb:NM_024525.1 NM_024525 tetratricopeptide repeat domain 13 TTC13 79573 NM_001122835 /// NM_024525 /// XM_005273260 /// XM_005273261 /// XM_005273262 /// XM_005273264 /// XM_006711814 /// XM_006711815 0005515 // protein binding // inferred from electronic annotation 219482_at NM_017438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017438.1 /DEF=Homo sapiens chromosome 21 open reading frame 18 (C21ORF18), mRNA. /FEA=mRNA /GEN=C21ORF18 /PROD=chromosome 21 open reading frame 18 /DB_XREF=gi:8393012 /UG=Hs.50748 chromosome 21 open reading frame 18 /FL=gb:NM_017438.1 NM_017438 SET domain containing 4 SETD4 54093 NM_001007258 /// NM_001007259 /// NM_001007260 /// NM_001007261 /// NM_001007262 /// NM_001286752 /// NM_017438 /// NR_040087 /// XM_005260999 /// XM_005261000 /// XM_005261001 /// XM_005261003 /// XM_006724021 /// XM_006724022 /// XM_006724023 /// XR_244283 /// XR_430350 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219483_s_at NM_022825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022825.1 /DEF=Homo sapiens porcupine (MG61), mRNA. /FEA=mRNA /GEN=MG61 /PROD=porcupine /DB_XREF=gi:12642982 /UG=Hs.5326 amino acid system N transporter 2; porcupine /FL=gb:AF317058.1 gb:AF317059.1 gb:NM_022825.1 NM_022825 porcupine homolog (Drosophila) PORCN 64840 NM_001282167 /// NM_022825 /// NM_203473 /// NM_203474 /// NM_203475 /// NM_203476 /// XM_005272635 /// XM_005272636 /// XM_005272637 /// XM_006724542 /// XM_006724543 /// XM_006724544 /// XM_006724545 /// XM_006724546 /// XM_006724547 /// XM_006724548 0008152 // metabolic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 219484_at NM_013320 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013320.1 /DEF=Homo sapiens host cell factor 2 (HCF-2), mRNA. /FEA=mRNA /GEN=HCF-2 /PROD=host cell factor 2 /DB_XREF=gi:7019404 /UG=Hs.55601 host cell factor 2 /FL=gb:AF117210.1 gb:NM_013320.1 NM_013320 host cell factor C2 HCFC2 29915 NM_013320 /// XR_245922 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016032 // viral process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219485_s_at NM_002814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002814.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (PSMD10), mRNA. /FEA=mRNA /GEN=PSMD10 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 10 /DB_XREF=gi:4506216 /UG=Hs.7756 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 /FL=gb:AB009619.1 gb:D83197.1 gb:NM_002814.1 NM_002814 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 PSMD10 5716 NM_002814 /// NM_170750 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007253 // cytoplasmic sequestering of NF-kappaB // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // inferred from mutant phenotype /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction 219486_at NM_017803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017803.1 /DEF=Homo sapiens hypothetical protein FLJ20399 (FLJ20399), mRNA. /FEA=mRNA /GEN=FLJ20399 /PROD=hypothetical protein FLJ20399 /DB_XREF=gi:8923373 /UG=Hs.8575 hypothetical protein FLJ20399 /FL=gb:NM_017803.1 NM_017803 dihydrouridine synthase 2 DUS2 54920 NM_001271762 /// NM_001271763 /// NM_017803 0002943 // tRNA dihydrouridine synthesis // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 219487_at NM_024685 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024685.1 /DEF=Homo sapiens hypothetical protein FLJ23560 (FLJ23560), mRNA. /FEA=mRNA /GEN=FLJ23560 /PROD=hypothetical protein FLJ23560 /DB_XREF=gi:13375955 /UG=Hs.96322 hypothetical protein FLJ23560 /FL=gb:NM_024685.1 NM_024685 Bardet-Biedl syndrome 10 BBS10 79738 NM_024685 /// XM_006719603 0001895 // retina homeostasis // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0035058 // nonmotile primary cilium assembly // inferred from mutant phenotype /// 0043254 // regulation of protein complex assembly // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051131 // chaperone-mediated protein complex assembly // inferred from mutant phenotype 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 219488_at NM_017436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017436.1 /DEF=Homo sapiens globotriaosylceramideCD77 synthase; Gb3CD77 synthase; alpha1,4-galactosyltransferase; 4-N-acetylglucosaminyltransferase (A14GALT), mRNA. /FEA=mRNA /GEN=A14GALT /PROD=globotriaosylceramideCD77 synthase; Gb3CD77synthase; alpha1,4-galactosyltransferase;4-N-acetylglucosaminyltransferase /DB_XREF=gi:8392829 /UG=Hs.105956 globotriaosylceramideCD77 synthase; Gb3CD77 synthase; alpha1,4-galactosyltransferase; 4-N-acetylglucosaminyltransferase /FL=gb:AB037883.1 gb:NM_017436.1 NM_017436 alpha 1,4-galactosyltransferase A4GALT 53947 NM_017436 /// XM_005261643 /// XM_005261644 /// XM_005261646 /// XM_005261647 /// XM_005261648 /// XM_006724265 /// XM_006724266 /// XM_006724267 0006486 // protein glycosylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // non-traceable author statement /// 0007009 // plasma membrane organization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008378 // galactosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0050512 // lactosylceramide 4-alpha-galactosyltransferase activity // inferred from electronic annotation 219489_s_at NM_017821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017821.1 /DEF=Homo sapiens hypothetical protein FLJ20435 (FLJ20435), mRNA. /FEA=mRNA /GEN=FLJ20435 /PROD=hypothetical protein FLJ20435 /DB_XREF=gi:8923408 /UG=Hs.11408 hypothetical protein FLJ20435 /FL=gb:NM_017821.1 NM_017821 nucleoredoxin NXN 64359 NM_001205319 /// NM_022463 /// XM_005256756 /// XM_005256757 /// XM_005256758 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004791 // thioredoxin-disulfide reductase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047134 // protein-disulfide reductase activity // inferred from electronic annotation 219490_s_at NM_022836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022836.1 /DEF=Homo sapiens hypothetical protein FLJ12810 (FLJ12810), mRNA. /FEA=mRNA /GEN=FLJ12810 /PROD=hypothetical protein FLJ12810 /DB_XREF=gi:12383081 /UG=Hs.115660 hypothetical protein FLJ12810 /FL=gb:NM_022836.1 NM_022836 DNA cross-link repair 1B DCLRE1B 64858 NM_022836 /// XM_005271130 0000075 // cell cycle checkpoint // inferred from mutant phenotype /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0031627 // telomeric loop formation // inferred from sequence or structural similarity /// 0031848 // protection from non-homologous end joining at telomere // inferred from mutant phenotype /// 0031860 // telomeric 3' overhang formation // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 219491_at NM_024036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024036.1 /DEF=Homo sapiens hypothetical protein MGC3103 (MGC3103), mRNA. /FEA=mRNA /GEN=MGC3103 /PROD=hypothetical protein MGC3103 /DB_XREF=gi:13128987 /UG=Hs.115960 hypothetical protein MGC3103 /FL=gb:BC000207.1 gb:NM_024036.1 NM_024036 leucine rich repeat and fibronectin type III domain containing 4 LRFN4 78999 NM_024036 /// XM_005274239 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219492_at NM_012110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012110.1 /DEF=Homo sapiens cystein-rich hydrophobic domain 2 (CHIC2), mRNA. /FEA=mRNA /GEN=CHIC2 /PROD=cystein-rich hydrophobic domain 2 /DB_XREF=gi:6912275 /UG=Hs.119488 cystein-rich hydrophobic domain 2 /FL=gb:AF159423.1 gb:NM_012110.1 NM_012110 cysteine-rich hydrophobic domain 2 CHIC2 26511 NM_012110 /// XM_005265738 /// XM_006714037 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219493_at NM_024745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024745.1 /DEF=Homo sapiens hypothetical protein FLJ22009 (FLJ22009), mRNA. /FEA=mRNA /GEN=FLJ22009 /PROD=hypothetical protein FLJ22009 /DB_XREF=gi:13376069 /UG=Hs.123253 hypothetical protein FLJ22009 /FL=gb:NM_024745.1 NM_024745 SHC SH2-domain binding protein 1 SHCBP1 79801 NM_024745 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 2000177 // regulation of neural precursor cell proliferation // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation 219494_at NM_012415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012415.1 /DEF=Homo sapiens RAD54, S. cerevisiae, homolog of, B (RAD54B), mRNA. /FEA=mRNA /GEN=RAD54B /PROD=RAD54, S. cerevisiae, homolog of, B /DB_XREF=gi:6912621 /UG=Hs.128501 RAD54, S. cerevisiae, homolog of, B /FL=gb:BC001965.1 gb:AF112481.1 gb:NM_012415.1 NM_012415 RAD54 homolog B (S. cerevisiae) RAD54B 25788 NM_001205262 /// NM_001205263 /// NM_006550 /// NM_012415 /// NM_134434 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006312 // mitotic recombination // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 219495_s_at NM_013256 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013256.1 /DEF=Homo sapiens zinc finger protein 180 (HHZ168) (ZNF180), mRNA. /FEA=mRNA /GEN=ZNF180 /PROD=zinc finger protein 180 (HHZ168) /DB_XREF=gi:7019578 /UG=Hs.130683 zinc finger protein 180 (HHZ168) /FL=gb:AF192913.1 gb:NM_013256.1 NM_013256 zinc finger protein 180 ZNF180 7733 NM_001278508 /// NM_001278509 /// NM_001288759 /// NM_001288760 /// NM_001288761 /// NM_001288762 /// NM_001291633 /// NM_013256 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219496_at NM_023016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023016.1 /DEF=Homo sapiens hypothetical protein FLJ21870 (FLJ21870), mRNA. /FEA=mRNA /GEN=FLJ21870 /PROD=hypothetical protein FLJ21870 /DB_XREF=gi:12711681 /UG=Hs.130815 hypothetical protein FLJ21870 /FL=gb:NM_023016.1 NM_023016 sosondowah ankyrin repeat domain family member C SOWAHC 65124 NM_023016 0005515 // protein binding // inferred from electronic annotation 219497_s_at NM_022893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022893.1 /DEF=Homo sapiens B-cell CLLlymphoma 11A (zinc finger protein) (BCL11A), mRNA. /FEA=mRNA /GEN=BCL11A /PROD=B-cell CLLlymphoma 11A (zinc finger protein) /DB_XREF=gi:13375629 /UG=Hs.130881 B-cell CLLlymphoma 11A (zinc finger protein) /FL=gb:NM_022893.1 gb:NM_018014.1 NM_022893 B-cell CLL/lymphoma 11A (zinc finger protein) BCL11A 53335 NM_018014 /// NM_022893 /// NM_138553 /// NM_138559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // non-traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0032463 // negative regulation of protein homooligomerization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048671 // negative regulation of collateral sprouting // inferred from mutant phenotype /// 0048672 // positive regulation of collateral sprouting // inferred from mutant phenotype /// 0050773 // regulation of dendrite development // inferred from mutant phenotype /// 2000171 // negative regulation of dendrite development // inferred from mutant phenotype /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 219498_s_at NM_018014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018014.1 /DEF=Homo sapiens B-cell CLLlymphoma 11A (zinc finger protein) (BCL11A), mRNA. /FEA=mRNA /GEN=BCL11A /PROD=hypothetical protein FLJ10173 /DB_XREF=gi:8922264 /UG=Hs.130881 B-cell CLLlymphoma 11A (zinc finger protein) /FL=gb:NM_022893.1 gb:NM_018014.1 NM_018014 B-cell CLL/lymphoma 11A (zinc finger protein) BCL11A 53335 NM_018014 /// NM_022893 /// NM_138553 /// NM_138559 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // non-traceable author statement /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0032463 // negative regulation of protein homooligomerization // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048671 // negative regulation of collateral sprouting // inferred from mutant phenotype /// 0048672 // positive regulation of collateral sprouting // inferred from mutant phenotype /// 0050773 // regulation of dendrite development // inferred from mutant phenotype /// 2000171 // negative regulation of dendrite development // inferred from mutant phenotype /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 219499_at NM_018144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018144.1 /DEF=Homo sapiens hypothetical protein FLJ10578 (FLJ10578), mRNA. /FEA=mRNA /GEN=FLJ10578 /PROD=hypothetical protein FLJ10578 /DB_XREF=gi:8922529 /UG=Hs.131840 hypothetical protein FLJ10578 /FL=gb:AF346603.1 gb:NM_018144.1 NM_018144 Sec61 alpha 2 subunit (S. cerevisiae) SEC61A2 55176 NM_001142627 /// NM_001142628 /// NM_018144 /// NR_024576 /// NR_024577 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0043022 // ribosome binding // inferred from electronic annotation 219500_at NM_013246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013246.1 /DEF=Homo sapiens cardiotrophin-like cytokine; neurotrophin-1B-cell stimulating factor-3 (CLC), mRNA. /FEA=mRNA /GEN=CLC /PROD=cardiotrophin-like cytokine;neurotrophin-1B-cell stimulating factor-3 /DB_XREF=gi:7019350 /UG=Hs.132004 cardiotrophin-like cytokine; neurotrophin-1B-cell stimulating factor-3 /FL=gb:AF172854.1 gb:AF176911.1 gb:NM_013246.1 NM_013246 cardiotrophin-like cytokine factor 1 CLCF1 23529 NM_001166212 /// NM_013246 0002639 // positive regulation of immunoglobulin production // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030890 // positive regulation of B cell proliferation // inferred from sequence or structural similarity /// 0040007 // growth // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097058 // CRLF-CLCF1 complex // inferred from direct assay /// 0097059 // CNTFR-CLCF1 complex // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // non-traceable author statement /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 219501_at NM_017993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017993.1 /DEF=Homo sapiens hypothetical protein FLJ10094 (FLJ10094), mRNA. /FEA=mRNA /GEN=FLJ10094 /PROD=hypothetical protein FLJ10094 /DB_XREF=gi:8922226 /UG=Hs.13209 hypothetical protein FLJ10094 /FL=gb:NM_017993.1 NM_017993 ecto-NOX disulfide-thiol exchanger 1 ENOX1 55068 NM_001127615 /// NM_001242863 /// NM_017993 /// XM_005266438 /// XM_005266439 /// XM_006719841 /// XM_006719842 0048511 // rhythmic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 219502_at NM_018248 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018248.1 /DEF=Homo sapiens hypothetical protein FLJ10858 (FLJ10858), mRNA. /FEA=mRNA /GEN=FLJ10858 /PROD=hypothetical protein FLJ10858 /DB_XREF=gi:8922721 /UG=Hs.134403 hypothetical protein FLJ10858 /FL=gb:NM_018248.1 NM_018248 nei endonuclease VIII-like 3 (E. coli) NEIL3 55247 NM_018248 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from sequence or structural similarity /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000405 // bubble DNA binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0019104 // DNA N-glycosylase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 219503_s_at NM_018306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018306.1 /DEF=Homo sapiens hypothetical protein FLJ11036 (FLJ11036), mRNA. /FEA=mRNA /GEN=FLJ11036 /PROD=hypothetical protein FLJ11036 /DB_XREF=gi:8922834 /UG=Hs.16740 hypothetical protein FLJ11036 /FL=gb:NM_018306.1 NM_018306 transmembrane protein 40 TMEM40 55287 NM_001284406 /// NM_001284407 /// NM_001284408 /// NM_018306 /// XM_006713249 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219504_s_at NM_024813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024813.1 /DEF=Homo sapiens hypothetical protein FLJ13150 (FLJ13150), mRNA. /FEA=mRNA /GEN=FLJ13150 /PROD=hypothetical protein FLJ13150 /DB_XREF=gi:13376201 /UG=Hs.169728 hypothetical protein FLJ13150 /FL=gb:NM_024813.1 NM_024813 RNA polymerase II associated protein 2 RPAP2 79871 NM_024813 /// XM_005271223 /// XM_006710905 /// XR_246295 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009301 // snRNA transcription // inferred from mutant phenotype /// 0070940 // dephosphorylation of RNA polymerase II C-terminal domain // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0008420 // CTD phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219505_at NM_017424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017424.1 /DEF=Homo sapiens cat eye syndrome chromosome region, candidate 1 (CECR1), mRNA. /FEA=mRNA /GEN=CECR1 /PROD=cat eye syndrome critical region protein 1 /DB_XREF=gi:8393092 /UG=Hs.170310 cat eye syndrome chromosome region, candidate 1 /FL=gb:AF190746.1 gb:NM_017424.1 NM_017424 cat eye syndrome chromosome region, candidate 1 CECR1 51816 NM_001282225 /// NM_001282226 /// NM_001282227 /// NM_001282228 /// NM_001282229 /// NM_017424 /// NM_177405 /// XM_006724080 0006154 // adenosine catabolic process // inferred from direct assay /// 0007275 // multicellular organismal development // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0043103 // hypoxanthine salvage // not recorded /// 0046103 // inosine biosynthetic process // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded 0004000 // adenosine deaminase activity // inferred from direct assay /// 0008083 // growth factor activity // not recorded /// 0008083 // growth factor activity // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043394 // proteoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219506_at NM_024579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024579.1 /DEF=Homo sapiens hypothetical protein FLJ23221 (FLJ23221), mRNA. /FEA=mRNA /GEN=FLJ23221 /PROD=hypothetical protein FLJ23221 /DB_XREF=gi:13375757 /UG=Hs.18397 hypothetical protein FLJ23221 /FL=gb:NM_024579.1 NM_024579 chromosome 1 open reading frame 54 C1orf54 79630 NM_024579 /// XM_005245488 /// XM_006711538 /// XM_006711539 /// XM_006711540 0005576 // extracellular region // inferred from electronic annotation 219507_at NM_016625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016625.1 /DEF=Homo sapiens hypothetical protein (LOC51319), mRNA. /FEA=mRNA /GEN=LOC51319 /PROD=hypothetical protein /DB_XREF=gi:7706163 /UG=Hs.191381 hypothetical protein /FL=gb:AF208853.1 gb:NM_016625.1 NM_016625 arginine/serine-rich coiled-coil 1 RSRC1 51319 NM_001271834 /// NM_001271838 /// NM_016625 /// XM_005247515 /// XM_005247516 /// XM_005247517 /// XM_005247518 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 219508_at NM_004751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004751.1 /DEF=Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA. /FEA=mRNA /GEN=GCNT3 /PROD=glucosaminyl (N-acetyl) transferase 3, mucintype /DB_XREF=gi:4758421 /UG=Hs.194710 glucosaminyl (N-acetyl) transferase 3, mucin type /FL=gb:AF102542.1 gb:AF038650.1 gb:NM_004751.1 NM_004751 glucosaminyl (N-acetyl) transferase 3, mucin type GCNT3 9245 NM_004751 0002426 // immunoglobulin production in mucosal tissue // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060993 // kidney morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003829 // beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008109 // N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047225 // acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation 219509_at NM_021245 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021245.1 /DEF=Homo sapiens myozenin (MYOZ), mRNA. /FEA=mRNA /GEN=MYOZ /PROD=myozenin /DB_XREF=gi:10864052 /UG=Hs.238756 myozenin /FL=gb:NM_021245.1 gb:AF240633.1 gb:AY013297.1 NM_021245 myozenin 1 MYOZ1 58529 NM_021245 0030239 // myofibril assembly // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051373 // FATZ binding // inferred from direct assay 219510_at NM_006596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006596.1 /DEF=Homo sapiens polymerase (DNA directed), theta (POLQ), mRNA. /FEA=mRNA /GEN=POLQ /PROD=polymerase (DNA directed), theta /DB_XREF=gi:5729983 /UG=Hs.241517 polymerase (DNA directed), theta /FL=gb:AF052573.1 gb:NM_006596.1 NM_006596 polymerase (DNA directed), theta POLQ 10721 NM_199420 /// XM_006713480 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from direct assay /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0043142 // single-stranded DNA-dependent ATPase activity // inferred from direct assay 219511_s_at NM_005460 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005460.1 /DEF=Homo sapiens synuclein, alpha interacting protein (synphilin) (SNCAIP), mRNA. /FEA=mRNA /GEN=SNCAIP /PROD=synuclein alpha interacting protein /DB_XREF=gi:4885602 /UG=Hs.24948 synuclein, alpha interacting protein (synphilin) /FL=gb:AF076929.1 gb:NM_005460.1 NM_005460 synuclein, alpha interacting protein SNCAIP 9627 NM_001242935 /// NM_005460 /// XM_005272138 /// XM_005272139 /// XM_006714734 /// XM_006714735 /// XM_006714736 /// XM_006714737 /// XM_006714738 0008219 // cell death // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from direct assay /// 0046928 // regulation of neurotransmitter secretion // inferred from direct assay /// 0090083 // regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0042734 // presynaptic membrane // non-traceable author statement /// 0043025 // neuronal cell body // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 219512_at NM_024918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024918.1 /DEF=Homo sapiens hypothetical protein FLJ13346 (FLJ13346), mRNA. /FEA=mRNA /GEN=FLJ13346 /PROD=hypothetical protein FLJ13346 /DB_XREF=gi:13376387 /UG=Hs.266273 hypothetical protein FLJ13346 /FL=gb:NM_024918.1 NM_024918 DSN1, MIS12 kinetochore complex component DSN1 79980 NM_001145315 /// NM_001145316 /// NM_001145317 /// NM_001145318 /// NM_024918 /// XM_005260558 /// XM_005260559 /// XM_006723876 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 219513_s_at NM_005490 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005490.1 /DEF=Homo sapiens novel SH2-containing protein 1 (NSP1), mRNA. /FEA=mRNA /GEN=NSP1 /PROD=novel SH2-containing protein 1 /DB_XREF=gi:4885524 /UG=Hs.268541 novel SH2-containing protein 1 /FL=gb:AF124249.1 gb:NM_005490.1 NM_005490 SH2 domain containing 3A SH2D3A 10045 NM_005490 /// XM_005259467 /// XM_005259472 /// XM_005259474 /// XM_006722602 0007254 // JNK cascade // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219514_at NM_012098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012098.1 /DEF=Homo sapiens angiopoietin-like 2 (ANGPTL2), mRNA. /FEA=mRNA /GEN=ANGPTL2 /PROD=angiopoietin-like 2 precursor /DB_XREF=gi:6912235 /UG=Hs.271877 angiopoietin-like 2 /FL=gb:AF125175.1 gb:NM_012098.1 NM_012098 angiopoietin-like 2 ANGPTL2 23452 NM_012098 /// XM_006717030 0007275 // multicellular organismal development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement 219515_at NM_020228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020228.1 /DEF=Homo sapiens PR domain containing 10 (PRDM10), mRNA. /FEA=mRNA /GEN=PRDM10 /PROD=PR domain containing 10 /DB_XREF=gi:9910503 /UG=Hs.275086 PR domain containing 10 /FL=gb:AF275817.1 gb:NM_020228.1 NM_020228 PR domain containing 10 PRDM10 56980 NM_020228 /// NM_199437 /// NM_199438 /// NM_199439 /// XM_006718886 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219516_at NM_021625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021625.2 /DEF=Homo sapiens vanilloid receptor-related osmotically activated channel; OTRPC4 protein (OTRPC4), mRNA. /FEA=mRNA /GEN=OTRPC4 /PROD=vanilloid receptor-related osmotically activatedchannel /DB_XREF=gi:13699862 /UG=Hs.287776 vanilloid receptor-related osmotically activated channel; OTRPC4 protein /FL=gb:AF258465.1 gb:AF263523.1 gb:NM_021625.2 NM_021625 transient receptor potential cation channel, subfamily V, member 4 TRPV4 59341 NM_001177428 /// NM_001177431 /// NM_001177433 /// NM_021625 /// NM_147204 /// XM_005253918 /// XM_005253919 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // non-traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006884 // cell volume homeostasis // traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006971 // hypotonic response // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007231 // osmosensory signaling pathway // inferred from sequence or structural similarity /// 0007231 // osmosensory signaling pathway // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030103 // vasopressin secretion // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0034605 // cellular response to heat // inferred from sequence or structural similarity /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0043622 // cortical microtubule organization // inferred from sequence or structural similarity /// 0046785 // microtubule polymerization // inferred from sequence or structural similarity /// 0047484 // regulation of response to osmotic stress // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070509 // calcium ion import // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071470 // cellular response to osmotic stress // inferred from sequence or structural similarity /// 0071476 // cellular hypotonic response // inferred from sequence or structural similarity 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005034 // osmosensor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043014 // alpha-tubulin binding // inferred from sequence or structural similarity /// 0048487 // beta-tubulin binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity 219517_at NM_025165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025165.1 /DEF=Homo sapiens hypothetical protein FLJ22637 (FLJ22637), mRNA. /FEA=mRNA /GEN=FLJ22637 /PROD=hypothetical protein FLJ22637 /DB_XREF=gi:13376767 /UG=Hs.296178 hypothetical protein FLJ22637 /FL=gb:NM_025165.1 NM_025165 elongation factor RNA polymerase II-like 3 ELL3 80237 NM_025165 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // non-traceable author statement /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 1901797 // negative regulation of signal transduction by p53 class mediator // inferred from electronic annotation /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0035326 // enhancer binding // inferred from sequence or structural similarity 219518_s_at NM_025165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025165.1 /DEF=Homo sapiens hypothetical protein FLJ22637 (FLJ22637), mRNA. /FEA=mRNA /GEN=FLJ22637 /PROD=hypothetical protein FLJ22637 /DB_XREF=gi:13376767 /UG=Hs.296178 hypothetical protein FLJ22637 /FL=gb:NM_025165.1 NM_025165 elongation factor RNA polymerase II-like 3 ELL3 80237 NM_025165 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // non-traceable author statement /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 1901797 // negative regulation of signal transduction by p53 class mediator // inferred from electronic annotation /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008023 // transcription elongation factor complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0035326 // enhancer binding // inferred from sequence or structural similarity 219519_s_at NM_023068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023068.1 /DEF=Homo sapiens sialoadhesin (SN), mRNA. /FEA=mRNA /GEN=SN /PROD=sialoadhesin /DB_XREF=gi:13489094 /UG=Hs.31869 sialoadhesin /FL=gb:AF230073.1 gb:NM_023068.1 NM_023068 sialic acid binding Ig-like lectin 1, sialoadhesin SIGLEC1 6614 NM_023068 /// XM_006723610 /// XM_006723611 /// XM_006723612 /// XM_006723613 0006897 // endocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0070234 // positive regulation of T cell apoptotic process // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement 219520_s_at NM_018458 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018458.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM042 (BM042), mRNA. /FEA=mRNA /GEN=BM042 /PROD=uncharacterized bone marrow protein BM042 /DB_XREF=gi:8922101 /UG=Hs.324136 uncharacterized bone marrow protein BM042 /FL=gb:AF217518.1 gb:NM_018458.1 NM_018458 WWC family member 3 WWC3 55841 NM_015691 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from mutant phenotype 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 219521_at NM_018644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018644.1 /DEF=Homo sapiens beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) (B3GAT1), mRNA. /FEA=mRNA /GEN=B3GAT1 /PROD=beta-1,3-glucuronyltransferase 1 /DB_XREF=gi:12408651 /UG=Hs.3353 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) /FL=gb:NM_018644.1 gb:AB029396.1 NM_018644 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) B3GAT1 27087 NM_018644 /// NM_054025 /// XM_005271506 /// XM_005271507 /// XM_005271508 /// XM_005271509 /// XM_005271510 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from electronic annotation /// 0015018 // galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219522_at NM_014344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014344.1 /DEF=Homo sapiens putative secreted ligand homologous to fjx1 (FJX1), mRNA. /FEA=mRNA /GEN=FJX1 /PROD=putative secreted ligand homologous to fjx1 /DB_XREF=gi:7657095 /UG=Hs.39384 putative secreted ligand homologous to fjx1 /FL=gb:NM_014344.1 NM_014344 four jointed box 1 (Drosophila) FJX1 24147 NM_014344 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 219523_s_at NM_018104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018104.1 /DEF=Homo sapiens hypothetical protein FLJ10474 (FLJ10474), mRNA. /FEA=mRNA /GEN=FLJ10474 /PROD=hypothetical protein FLJ10474 /DB_XREF=gi:8922443 /UG=Hs.41793 hypothetical protein FLJ10474 /FL=gb:NM_018104.1 NM_018104 teneurin transmembrane protein 3 TENM3 55714 NM_001080477 /// XM_006714256 /// XM_006714257 /// XM_006714258 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from mutant phenotype 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 219524_s_at NM_024120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024120.1 /DEF=Homo sapiens hypothetical protein FLJ22324 (FLJ22324), mRNA. /FEA=mRNA /GEN=FLJ22324 /PROD=hypothetical protein FLJ22324 /DB_XREF=gi:13129143 /UG=Hs.44296 hypothetical protein FLJ22324 /FL=gb:NM_024120.1 NM_024120 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 NDUFAF5 79133 NM_001039375 /// NM_024120 /// NM_199052 /// NR_029377 /// XM_006723620 /// XM_006723621 /// XM_006723622 /// XM_006723623 /// XM_006723624 /// XR_430269 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031314 // extrinsic component of mitochondrial inner membrane // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219525_at NM_018242 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018242.1 /DEF=Homo sapiens hypothetical protein FLJ10847 (FLJ10847), mRNA. /FEA=mRNA /GEN=FLJ10847 /PROD=hypothetical protein FLJ10847 /DB_XREF=gi:8922708 /UG=Hs.48403 hypothetical protein FLJ10847 /FL=gb:NM_018242.1 NM_018242 solute carrier family 47 (multidrug and toxin extrusion), member 1 SLC47A1 55244 NM_018242 0006810 // transport // inferred from electronic annotation /// 0006855 // drug transmembrane transport // inferred from electronic annotation /// 0015695 // organic cation transport // inferred from electronic annotation /// 0015893 // drug transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0005451 // monovalent cation:proton antiporter activity // inferred from electronic annotation /// 0015238 // drug transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 219526_at NM_024644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024644.1 /DEF=Homo sapiens hypothetical protein FLJ21802 (FLJ21802), mRNA. /FEA=mRNA /GEN=FLJ21802 /PROD=hypothetical protein FLJ21802 /DB_XREF=gi:13375884 /UG=Hs.48938 hypothetical protein FLJ21802 /FL=gb:NM_024644.1 NM_024644 chromosome 14 open reading frame 169 C14orf169 79697 NM_024644 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0005506 // iron ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from sequence or structural similarity /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from sequence or structural similarity 219527_at NM_017898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017898.1 /DEF=Homo sapiens hypothetical protein FLJ20605 (FLJ20605), mRNA. /FEA=mRNA /GEN=FLJ20605 /PROD=hypothetical protein FLJ20605 /DB_XREF=gi:8923560 /UG=Hs.4932 hypothetical protein FLJ20605 /FL=gb:NM_017898.1 NM_017898 mitochondrial amidoxime reducing component 2 MARC2 54996 NM_017898 /// XM_005273168 /// XM_006711407 /// XR_247029 0008152 // metabolic process // inferred from electronic annotation /// 0042126 // nitrate metabolic process // inferred from direct assay /// 0051410 // detoxification of nitrogen compound // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008940 // nitrate reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from direct assay 219528_s_at NM_022898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022898.1 /DEF=Homo sapiens B-cell lymphomaleukaemia 11B (BCL11B), mRNA. /FEA=mRNA /GEN=BCL11B /PROD=B-cell lymphomaleukaemia 11B /DB_XREF=gi:12597634 /UG=Hs.57987 B-cell CLLlymphoma 11B (zinc finger protein) /FL=gb:NM_022898.1 NM_022898 B-cell CLL/lymphoma 11B (zinc finger protein) BCL11B 64919 NM_001282237 /// NM_001282238 /// NM_022898 /// NM_138576 0003334 // keratinocyte development // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010837 // regulation of keratinocyte proliferation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021773 // striatal medium spiny neuron differentiation // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0031077 // post-embryonic camera-type eye development // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043368 // positive T cell selection // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0071678 // olfactory bulb axon guidance // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219529_at NM_004669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004669.1 /DEF=Homo sapiens chloride intracellular channel 3 (CLIC3), mRNA. /FEA=mRNA /GEN=CLIC3 /PROD=chloride intracellular channel 3 /DB_XREF=gi:4758005 /UG=Hs.64746 chloride intracellular channel 3 /FL=gb:AF102166.1 gb:NM_004669.1 NM_004669 chloride intracellular channel 3 CLIC3 9022 NM_004669 /// XM_005266117 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 219530_at NM_024675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024675.1 /DEF=Homo sapiens hypothetical protein FLJ21816 (FLJ21816), mRNA. /FEA=mRNA /GEN=FLJ21816 /PROD=hypothetical protein FLJ21816 /DB_XREF=gi:13375939 /UG=Hs.86434 hypothetical protein FLJ21816 /FL=gb:NM_024675.1 NM_024675 partner and localizer of BRCA2 PALB2 79728 NM_024675 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219531_at NM_018140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018140.1 /DEF=Homo sapiens hypothetical protein FLJ10565 (FLJ10565), mRNA. /FEA=mRNA /GEN=FLJ10565 /PROD=hypothetical protein FLJ10565 /DB_XREF=gi:8922520 /UG=Hs.100824 hypothetical protein FLJ10565 /FL=gb:BC000132.2 gb:BC001750.1 gb:NM_018140.1 NM_018140 centrosomal protein 72kDa CEP72 55722 NM_018140 /// XM_005248321 /// XM_005248322 /// XM_005248323 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007051 // spindle organization // inferred from mutant phenotype /// 0033566 // gamma-tubulin complex localization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 219532_at NM_022726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022726.1 /DEF=Homo sapiens Stargardt disease 3 (autosomal dominant) (ELOVL4), mRNA. /FEA=mRNA /GEN=ELOVL4 /PROD=Stargardt disease 3 (autosomal dominant) /DB_XREF=gi:12232378 /UG=Hs.101915 Stargardt disease 3 (autosomal dominant) /FL=gb:AF277094.1 gb:NM_022726.1 NM_022726 ELOVL fatty acid elongase 4 ELOVL4 6785 NM_022726 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // non-traceable author statement /// 0009584 // detection of visible light // non-traceable author statement /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008020 // G-protein coupled photoreceptor activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 219533_at NM_000076 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000076.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), mRNA. /FEA=mRNA /GEN=CDKN1C /PROD=cyclin-dependent kinase inhibitor 1C /DB_XREF=gi:4557440 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) /FL=gb:NM_000076.1 gb:U22398.1 NM_000076 219534_x_at NM_000076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000076.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), mRNA. /FEA=mRNA /GEN=CDKN1C /PROD=cyclin-dependent kinase inhibitor 1C /DB_XREF=gi:4557440 /UG=Hs.106070 cyclin-dependent kinase inhibitor 1C (p57, Kip2) /FL=gb:NM_000076.1 gb:U22398.1 NM_000076 cyclin-dependent kinase inhibitor 1C (p57, Kip2) CDKN1C 1028 NM_000076 /// NM_001122630 /// NM_001122631 /// XM_005252731 /// XM_005252732 /// XM_006725125 /// XM_006725126 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000080 // mitotic G1 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from genetic interaction /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 219535_at NM_014586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014586.1 /DEF=Homo sapiens hormonally upregulated neu tumor-associated kinase (HUNK), mRNA. /FEA=mRNA /GEN=HUNK /PROD=hormonally upregulated neu tumor-associatedkinase /DB_XREF=gi:7657213 /UG=Hs.109437 hormonally upregulated neu tumor-associated kinase /FL=gb:NM_014586.1 NM_014586 hormonally up-regulated Neu-associated kinase HUNK 30811 NM_014586 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 219536_s_at NM_022088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022088.1 /DEF=Homo sapiens hypothetical protein FLJ12628 (FLJ12628), mRNA. /FEA=mRNA /GEN=FLJ12628 /PROD=hypothetical protein FLJ12628 /DB_XREF=gi:11545802 /UG=Hs.124109 hypothetical protein FLJ12628 /FL=gb:NM_022088.1 NM_022088 ZFP64 zinc finger protein ZFP64 55734 NM_018197 /// NM_022088 /// NM_199426 /// NM_199427 /// XM_005260449 /// XM_005260450 /// XM_006723821 /// XM_006723822 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219537_x_at NM_016941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016941.1 /DEF=Homo sapiens delta (Drosophila)-like 3 (DLL3), mRNA. /FEA=mRNA /GEN=DLL3 /PROD=delta-like 3 protein precursor /DB_XREF=gi:8393263 /UG=Hs.127792 delta (Drosophila)-like 3 /FL=gb:BC000218.1 gb:NM_016941.1 NM_016941 delta-like 3 (Drosophila) DLL3 10683 NM_016941 /// NM_203486 0001501 // skeletal system development // inferred from mutant phenotype /// 0001756 // somitogenesis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007386 // compartment pattern specification // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005112 // Notch binding // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219538_at NM_019069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019069.1 /DEF=Homo sapiens hypothetical protein (FLJ11287), mRNA. /FEA=mRNA /GEN=FLJ11287 /PROD=hypothetical protein /DB_XREF=gi:9506644 /UG=Hs.142395 hypothetical protein /FL=gb:NM_019069.1 NM_019069 WD repeat domain 5B WDR5B 54554 NM_019069 0005515 // protein binding // inferred from electronic annotation 219539_at NM_024775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024775.1 /DEF=Homo sapiens hypothetical protein FLJ23459 (FLJ23459), mRNA. /FEA=mRNA /GEN=FLJ23459 /PROD=hypothetical protein FLJ23459 /DB_XREF=gi:13376126 /UG=Hs.143818 hypothetical protein FLJ23459 /FL=gb:NM_024775.1 NM_024775 gem (nuclear organelle) associated protein 6 GEMIN6 79833 NM_024775 /// XM_005264568 0000245 // spliceosomal complex assembly // inferred from electronic annotation /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from electronic annotation /// 0016604 // nuclear body // inferred from direct assay /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219540_at AU150728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU150728 /FEA=EST /DB_XREF=gi:11012249 /DB_XREF=est:AU150728 /CLONE=NT2RP2003470 /UG=Hs.145498 zinc finger protein 267 /FL=gb:NM_003414.2 gb:AF220492.1 AU150728 zinc finger protein 267 ZNF267 10308 NM_001265588 /// NM_003414 /// NR_049749 /// XM_006721005 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219541_at NM_017806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017806.1 /DEF=Homo sapiens hypothetical protein FLJ20406 (FLJ20406), mRNA. /FEA=mRNA /GEN=FLJ20406 /PROD=hypothetical protein FLJ20406 /DB_XREF=gi:8923377 /UG=Hs.149227 hypothetical protein FLJ20406 /FL=gb:NM_017806.1 NM_017806 Lck interacting transmembrane adaptor 1 LIME1 54923 NM_017806 0002376 // immune system process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0014066 // regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043405 // regulation of MAP kinase activity // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019815 // B cell receptor complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219542_at NM_024800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024800.1 /DEF=Homo sapiens hypothetical protein FLJ23495 (FLJ23495), mRNA. /FEA=mRNA /GEN=FLJ23495 /PROD=hypothetical protein FLJ23495 /DB_XREF=gi:13376174 /UG=Hs.159146 hypothetical protein FLJ23495 /FL=gb:NM_024800.1 NM_024800 NIMA-related kinase 11 NEK11 79858 NM_001146003 /// NM_024800 /// NM_145910 /// XM_005247783 /// XM_005247785 /// XM_006713749 /// XM_006713750 /// XM_006713751 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0031573 // intra-S DNA damage checkpoint // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219543_at NM_022129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022129.1 /DEF=Homo sapiens MAWD binding protein (MAWBP), mRNA. /FEA=mRNA /GEN=MAWBP /PROD=MAWD binding protein /DB_XREF=gi:11545856 /UG=Hs.16341 MAWD binding protein /FL=gb:AB049758.1 gb:NM_022129.1 NM_022129 phenazine biosynthesis-like protein domain containing PBLD 64081 NM_001033083 /// NM_022129 /// XM_005270028 /// XM_005270029 0009058 // biosynthetic process // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0060392 // negative regulation of SMAD protein import into nucleus // inferred from genetic interaction /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 219544_at NM_024808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024808.1 /DEF=Homo sapiens hypothetical protein FLJ22624 (FLJ22624), mRNA. /FEA=mRNA /GEN=FLJ22624 /PROD=hypothetical protein FLJ22624 /DB_XREF=gi:13376190 /UG=Hs.166425 hypothetical protein FLJ22624 /FL=gb:NM_024808.1 NM_024808 bora, aurora kinase A activator BORA 79866 NM_001286746 /// NM_001286747 /// NM_024808 /// XM_006719868 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0060236 // regulation of mitotic spindle organization // inferred from mutant phenotype 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 219545_at NM_023930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023930.1 /DEF=Homo sapiens hypothetical protein MGC2376 (MGC2376), mRNA. /FEA=mRNA /GEN=MGC2376 /PROD=hypothetical protein MGC2376 /DB_XREF=gi:13027591 /UG=Hs.17296 hypothetical protein MGC2376 /FL=gb:BC001062.1 gb:BC001929.1 gb:NM_023930.1 NM_023930 potassium channel tetramerization domain containing 14 /// NDUFC2-KCTD14 readthrough KCTD14 /// NDUFC2-KCTD14 65987 /// 100532726 NM_001203260 /// NM_001203261 /// NM_001203262 /// NM_001282406 /// NM_023930 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation 219546_at NM_017593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017593.1 /DEF=Homo sapiens hypothetical protein DKFZp434P0116 (DKFZp434P0116), mRNA. /FEA=mRNA /GEN=DKFZp434P0116 /PROD=hypothetical protein DKFZp434P0116 /DB_XREF=gi:9055205 /UG=Hs.20137 hypothetical protein DKFZp434P0116 /FL=gb:NM_017593.1 NM_017593 BMP2 inducible kinase BMP2K 55589 NM_017593 /// NM_198892 /// XM_005263117 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from physical interaction /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // inferred from electronic annotation 219547_at NM_004376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004376.1 /DEF=Homo sapiens COX15 (yeast) homolog, cytochrome c oxidase assembly protein (COX15), mRNA. /FEA=mRNA /GEN=COX15 /PROD=COX15 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:4758035 /UG=Hs.226581 COX15 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:AF044323.1 gb:NM_004376.1 NM_004376 cytochrome c oxidase assembly homolog 15 (yeast) COX15 1355 NM_004376 /// NM_078470 /// XM_005269539 /// XM_006717633 /// XM_006717634 0006123 // mitochondrial electron transport, cytochrome c to oxygen // inferred by curator /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006784 // heme a biosynthetic process // inferred from electronic annotation /// 0006784 // heme a biosynthetic process // inferred from genetic interaction /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred by curator /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from genetic interaction /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004129 // cytochrome-c oxidase activity // inferred from genetic interaction /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation 219548_at NM_006958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006958.1 /DEF=Homo sapiens zinc finger protein 16 (KOX 9) (ZNF16), mRNA. /FEA=mRNA /GEN=ZNF16 /PROD=zinc finger protein 16 (KOX 9) /DB_XREF=gi:11177859 /UG=Hs.23019 zinc finger protein 16 (KOX 9) /FL=gb:NM_006958.1 gb:AF244088.1 NM_006958 zinc finger protein 16 ZNF16 7564 NM_001029976 /// NM_006958 /// XM_005272341 /// XM_005272342 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0072707 // cellular response to sodium dodecyl sulfate // inferred from direct assay /// 1901989 // positive regulation of cell cycle phase transition // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219549_s_at NM_006054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006054.1 /DEF=Homo sapiens reticulon 3 (RTN3), mRNA. /FEA=mRNA /GEN=RTN3 /PROD=reticulon 3 /DB_XREF=gi:5174654 /UG=Hs.252831 reticulon 3 /FL=gb:BC000634.1 gb:AF059524.1 gb:AF119297.1 gb:NM_006054.1 NM_006054 reticulon 3 RTN3 10313 NM_001265589 /// NM_001265590 /// NM_001265591 /// NM_006054 /// NM_201428 /// NM_201429 /// NM_201430 /// NR_049750 /// NR_049751 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from physical interaction 219550_at NM_022370 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022370.1 /DEF=Homo sapiens hypothetical protein FLJ21044 similar to Rbig1 (FLJ21044), mRNA. /FEA=mRNA /GEN=FLJ21044 /PROD=hypothetical protein FLJ21044 similar to Rbig1 /DB_XREF=gi:11641296 /UG=Hs.25477 hypothetical protein FLJ21044 similar to Rbig1 /FL=gb:NM_022370.1 NM_022370 roundabout, axon guidance receptor, homolog 3 (Drosophila) ROBO3 64221 NM_022370 0001764 // neuron migration // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 219551_at NM_018456 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018456.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM040 (BM040), mRNA. /FEA=mRNA /GEN=BM040 /PROD=uncharacterized bone marrow protein BM040 /DB_XREF=gi:8922098 /UG=Hs.26892 uncharacterized bone marrow protein BM040 /FL=gb:AF217516.1 gb:NM_018456.1 NM_018456 ELL associated factor 2 EAF2 55840 NM_018456 /// XM_005247618 /// XM_005247620 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0032783 // ELL-EAF complex // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219552_at NM_024500 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024500.1 /DEF=Homo sapiens likely ortholog of mouse polydom (POLYDOM), mRNA. /FEA=mRNA /GEN=POLYDOM /PROD=likely ortholog of mouse polydom /DB_XREF=gi:13374570 /UG=Hs.271350 likely ortholog of mouse polydom /FL=gb:NM_024500.1 NM_024500 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 SVEP1 79987 NM_153366 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 219553_at NM_013330 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013330.2 /DEF=Homo sapiens NME7 (NME7), mRNA. /FEA=mRNA /GEN=NME7 /PROD=NME7 /DB_XREF=gi:7242158 /UG=Hs.274479 NME7 /FL=gb:AF153191.2 gb:NM_013330.2 NM_013330 NME/NM23 family member 7 NME7 29922 NM_013330 /// NM_197972 /// NR_104229 /// XM_005245106 0003351 // epithelial cilium movement // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // inferred from electronic annotation /// 0060972 // left/right pattern formation // inferred from electronic annotation 0005813 // centrosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219554_at NM_016321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016321.1 /DEF=Homo sapiens Rh type C glycoprotein (RHCG), mRNA. /FEA=mRNA /GEN=RHCG /PROD=Rh type C glycoprotein /DB_XREF=gi:7706682 /UG=Hs.279682 Rh type C glycoprotein /FL=gb:AF081497.1 gb:AF193809.1 gb:NM_016321.1 NM_016321 Rh family, C glycoprotein RHCG 51458 NM_016321 /// NR_110261 0006810 // transport // inferred from electronic annotation /// 0006873 // cellular ion homeostasis // inferred from direct assay /// 0006885 // regulation of pH // inferred from electronic annotation /// 0015696 // ammonium transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from genetic interaction /// 0015837 // amine transport // non-traceable author statement /// 0030855 // epithelial cell differentiation // non-traceable author statement /// 0042592 // homeostatic process // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070634 // transepithelial ammonium transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from genetic interaction 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0008519 // ammonium transmembrane transporter activity // inferred from genetic interaction /// 0030506 // ankyrin binding // inferred from direct assay 219555_s_at NM_018455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018455.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM039 (BM039), mRNA. /FEA=mRNA /GEN=BM039 /PROD=uncharacterized bone marrow protein BM039 /DB_XREF=gi:8922096 /UG=Hs.283532 uncharacterized bone marrow protein BM039 /FL=gb:AF217515.1 gb:NM_018455.1 NM_018455 centromere protein N CENPN 55839 NM_001100624 /// NM_001100625 /// NM_001270473 /// NM_001270474 /// NM_018455 /// XM_006721236 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034508 // centromere complex assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 219556_at NM_025108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025108.1 /DEF=Homo sapiens hypothetical protein FLJ13909 (FLJ13909), mRNA. /FEA=mRNA /GEN=FLJ13909 /PROD=hypothetical protein FLJ13909 /DB_XREF=gi:13376678 /UG=Hs.288672 hypothetical protein FLJ13909 /FL=gb:NM_025108.1 NM_025108 chromosome 16 open reading frame 59 C16orf59 80178 NM_025108 /// XM_006720955 219557_s_at NM_020645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020645.1 /DEF=Homo sapiens chromosome 11 open reading frame 14 (C11ORF14), mRNA. /FEA=mRNA /GEN=C11ORF14 /PROD=chromosome 11 open reading frame 14 /DB_XREF=gi:11034818 /UG=Hs.32017 chromosome 11 open reading frame 14 /FL=gb:NM_020645.1 NM_020645 nuclear receptor interacting protein 3 NRIP3 56675 NM_020645 0006508 // proteolysis // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation 219558_at NM_024524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024524.1 /DEF=Homo sapiens hypothetical protein FLJ20986 (FLJ20986), mRNA. /FEA=mRNA /GEN=FLJ20986 /PROD=hypothetical protein FLJ20986 /DB_XREF=gi:13375667 /UG=Hs.324507 hypothetical protein FLJ20986 /FL=gb:NM_024524.1 NM_024524 ATPase type 13A3 ATP13A3 79572 NM_024524 /// XM_005269357 /// XM_005269358 /// XM_005269360 /// XM_006713742 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219559_at NM_022082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022082.1 /DEF=Homo sapiens hypothetical protein FLJ23412 (FLJ23412), mRNA. /FEA=mRNA /GEN=FLJ23412 /PROD=hypothetical protein FLJ23412 /DB_XREF=gi:11545794 /UG=Hs.34487 hypothetical protein FLJ23412 /FL=gb:NM_022082.1 NM_022082 solute carrier family 17 (vesicular nucleotide transporter), member 9 SLC17A9 63910 NM_022082 /// XM_005260228 /// XM_006723853 /// XR_430309 /// XR_430310 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 219560_at NM_024627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024627.1 /DEF=Homo sapiens hypothetical protein FLJ21125 (FLJ21125), mRNA. /FEA=mRNA /GEN=FLJ21125 /PROD=hypothetical protein FLJ21125 /DB_XREF=gi:13375851 /UG=Hs.36574 hypothetical protein FLJ21125 /FL=gb:NM_024627.1 NM_024627 chromosome 22 open reading frame 29 /// guanine nucleotide binding protein (G protein), beta polypeptide 1-like C22orf29 /// GNB1L 54584 /// 79680 NM_024627 /// NM_053004 0006915 // apoptotic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0035176 // social behavior // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 219561_at NM_016429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016429.1 /DEF=Homo sapiens COPZ2 for nonclathrin coat protein zeta-COP (LOC51226), mRNA. /FEA=mRNA /GEN=LOC51226 /PROD=COPZ2 for nonclathrin coat protein zeta-COP /DB_XREF=gi:7705982 /UG=Hs.37482 COPZ2 for nonclathrin coat protein zeta-COP /FL=gb:AB047849.1 gb:AB037938.1 gb:NM_016429.1 NM_016429 coatomer protein complex, subunit zeta 2 COPZ2 51226 NM_016429 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030126 // COPI vesicle coat // non-traceable author statement /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 219562_at NM_014353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014353.1 /DEF=Homo sapiens RAB26, member RAS oncogene family (RAB26), mRNA. /FEA=mRNA /GEN=RAB26 /PROD=RAB26, member RAS oncogene family /DB_XREF=gi:7657491 /UG=Hs.3797 RAB26, member RAS oncogene family /FL=gb:AB027137.1 gb:NM_014353.1 NM_014353 RAB26, member RAS oncogene family RAB26 25837 NM_014353 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from sequence or structural similarity /// 0035272 // exocrine system development // inferred from mutant phenotype /// 0035272 // exocrine system development // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from sequence or structural similarity /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from mutant phenotype /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019002 // GMP binding // inferred from mutant phenotype 219563_at NM_024633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024633.1 /DEF=Homo sapiens hypothetical protein FLJ21276 (FLJ21276), mRNA. /FEA=mRNA /GEN=FLJ21276 /PROD=hypothetical protein FLJ21276 /DB_XREF=gi:13375863 /UG=Hs.41502 hypothetical protein FLJ21276 /FL=gb:NM_024633.1 NM_024633 long intergenic non-protein coding RNA 341 /// spectrin repeat containing, nuclear envelope family member 3 LINC00341 /// SYNE3 79686 /// 161176 NM_024633 /// NM_152592 /// NR_026779 /// XM_005267376 /// XM_005267377 /// XM_006720063 /// XM_006720064 /// XM_006720065 /// XM_006720066 /// XM_006720067 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0090150 // establishment of protein localization to membrane // inferred from direct assay /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034993 // SUN-KASH complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from mutant phenotype 219564_at NM_018658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018658.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 16 (KCNJ16), mRNA. /FEA=mRNA /GEN=KCNJ16 /PROD=potassium inwardly-rectifying channel, subfamilyJ, member 16 /DB_XREF=gi:8923822 /UG=Hs.50151 potassium inwardly-rectifying channel, subfamily J, member 16 /FL=gb:AF153815.1 gb:AF153816.1 gb:NM_018658.1 gb:AF179353.1 NM_018658 potassium inwardly-rectifying channel, subfamily J, member 16 KCNJ16 3773 NM_001270422 /// NM_001291622 /// NM_001291623 /// NM_001291624 /// NM_001291625 /// NM_018658 /// NM_170741 /// NM_170742 /// XM_005257334 /// XM_005257335 /// XM_005257336 /// XM_005257337 /// XM_005257339 /// XM_005257340 /// XM_006721882 /// XM_006721883 /// XM_006721884 /// XM_006721885 /// XM_006721886 /// XM_006721887 /// XM_006721888 /// XM_006721889 /// XM_006721890 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // non-traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 219565_at NM_020674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020674.1 /DEF=Homo sapiens cytochrome P450 monooxygenase (LOC57404), mRNA. /FEA=mRNA /GEN=LOC57404 /PROD=cytochrome P450 monooxygenase /DB_XREF=gi:10257438 /UG=Hs.50335 cytochrome P450 monooxygenase /FL=gb:NM_020674.1 gb:AF183412.1 NM_020674 cytochrome P450, family 20, subfamily A, polypeptide 1 CYP20A1 57404 NM_020674 /// NM_177538 /// XM_005246698 /// XM_005246699 /// XM_005246700 /// XM_005246701 /// XM_006712644 /// XM_006712645 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219566_at NM_024310 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024310.1 /DEF=Homo sapiens hypothetical protein MGC4090 (MGC4090), mRNA. /FEA=mRNA /GEN=MGC4090 /PROD=hypothetical protein MGC4090 /DB_XREF=gi:13236546 /UG=Hs.58389 hypothetical protein MGC4090 /FL=gb:BC002744.1 gb:NM_024310.1 NM_024310 pleckstrin homology domain containing, family F (with FYVE domain) member 1 PLEKHF1 79156 NM_024310 /// XM_005259256 /// XM_006723378 0006915 // apoptotic process // inferred from electronic annotation /// 0007032 // endosome organization // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from direct assay /// 0016050 // vesicle organization // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred by curator /// 0005768 // endosome // inferred from direct assay /// 0010008 // endosome membrane // inferred by curator /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay 219567_s_at NM_022774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022774.1 /DEF=Homo sapiens hypothetical protein FLJ21144 (FLJ21144), mRNA. /FEA=mRNA /GEN=FLJ21144 /PROD=hypothetical protein FLJ21144 /DB_XREF=gi:12232456 /UG=Hs.59584 hypothetical protein FLJ21144 /FL=gb:NM_022774.1 NM_022774 exonuclease 5 EXO5 64789 NM_022774 /// XM_005271125 /// XM_005271126 /// XM_005271128 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0036297 // interstrand cross-link repair // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008310 // single-stranded DNA 3'-5' exodeoxyribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0045145 // single-stranded DNA 5'-3' exodeoxyribonuclease activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 219568_x_at NM_018419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018419.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 18 (SOX18), mRNA. /FEA=mRNA /GEN=SOX18 /PROD=SRY (sex determining region Y)-box 18 /DB_XREF=gi:8924247 /UG=Hs.8619 SRY (sex determining region Y)-box 18 /FL=gb:AF270652.1 gb:AB033888.1 gb:NM_018419.1 NM_018419 SRY (sex determining region Y)-box 18 SOX18 54345 NM_018419 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0001946 // lymphangiogenesis // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0022405 // hair cycle process // inferred from mutant phenotype /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0043534 // blood vessel endothelial cell migration // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048469 // cell maturation // inferred from electronic annotation /// 0048866 // stem cell fate specification // inferred from electronic annotation /// 0060214 // endocardium formation // inferred from sequence or structural similarity /// 0060836 // lymphatic endothelial cell differentiation // inferred from sequence or structural similarity /// 0060956 // endocardial cell differentiation // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0072091 // regulation of stem cell proliferation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 219569_s_at NM_025246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025246.1 /DEF=Homo sapiens hypothetical protein MGC3295 (MGC3295), mRNA. /FEA=mRNA /GEN=MGC3295 /PROD=hypothetical protein MGC3295 /DB_XREF=gi:13376859 /UG=Hs.101257 hypothetical protein MGC3295 /FL=gb:AL136661.1 gb:NM_025246.1 NM_025246 solute carrier family 35, member G2 SLC35G2 80723 NM_001097599 /// NM_001097600 /// NM_025246 /// XM_006713773 /// XM_006713774 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219570_at NM_024704 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024704.1 /DEF=Homo sapiens hypothetical protein FLJ23045 (FLJ23045), mRNA. /FEA=mRNA /GEN=FLJ23045 /PROD=hypothetical protein FLJ23045 /DB_XREF=gi:13375994 /UG=Hs.101774 hypothetical protein FLJ23045 /FL=gb:NM_024704.1 NM_024704 kinesin family member 16B KIF16B 55614 NM_001199865 /// NM_001199866 /// NM_024704 /// XM_005260750 /// XM_005260751 /// XM_005260752 /// XM_005260753 /// XM_005260754 /// XM_005260755 /// XM_006723588 0001704 // formation of primary germ layer // inferred from sequence or structural similarity /// 0001919 // regulation of receptor recycling // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007492 // endoderm development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032801 // receptor catabolic process // inferred from mutant phenotype /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008574 // plus-end-directed microtubule motor activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 219571_s_at NM_016265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016265.1 /DEF=Homo sapiens GIOT-3 for gonadotropin inducible transcription repressor-3 (GIOT-3), mRNA. /FEA=mRNA /GEN=GIOT-3 /PROD=GIOT-3 for gonadotropin inducible transcriptionrepressor-3 /DB_XREF=gi:7706464 /UG=Hs.102397 GIOT-3 for gonadotropin inducible transcription repressor-3 /FL=gb:AB021643.1 gb:NM_016265.1 NM_016265 zinc finger protein 12 ZNF12 7559 NM_006956 /// NM_016265 /// XR_242099 /// XR_242100 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219572_at NM_017954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017954.1 /DEF=Homo sapiens hypothetical protein FLJ20761 (FLJ20761), mRNA. /FEA=mRNA /GEN=FLJ20761 /PROD=hypothetical protein FLJ20761 /DB_XREF=gi:8923671 /UG=Hs.107872 hypothetical protein FLJ20761 /FL=gb:NM_017954.1 NM_017954 Ca++-dependent secretion activator 2 CADPS2 93664 NM_001009571 /// NM_001167940 /// NM_017954 /// XM_005250695 /// XM_005250696 /// XM_005250697 /// XM_005250698 /// XM_005250699 /// XM_005250700 /// XM_005250701 /// XM_005250702 /// XM_005250703 /// XM_005250704 /// XM_005250705 /// XM_005250706 /// XM_005250707 /// XM_005250708 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219573_at NM_017640 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017640.1 /DEF=Homo sapiens hypothetical protein FLJ20048 (FLJ20048), mRNA. /FEA=mRNA /GEN=FLJ20048 /PROD=hypothetical protein FLJ20048 /DB_XREF=gi:8923056 /UG=Hs.116470 hypothetical protein FLJ20048 /FL=gb:NM_017640.1 NM_017640 leucine rich repeat containing 16A LRRC16A 55604 NM_001173977 /// NM_017640 /// XM_005249218 /// XM_006715136 /// XM_006715137 /// XM_006715138 /// XM_006715139 /// XM_006715140 0007015 // actin filament organization // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from mutant phenotype /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051638 // barbed-end actin filament uncapping // inferred from sequence or structural similarity /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 1902745 // positive regulation of lamellipodium organization // inferred from direct assay /// 2000813 // negative regulation of barbed-end actin filament capping // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0032403 // protein complex binding // inferred from direct assay 219574_at NM_017923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017923.1 /DEF=Homo sapiens hypothetical protein FLJ20668 (FLJ20668), mRNA. /FEA=mRNA /GEN=FLJ20668 /PROD=hypothetical protein FLJ20668 /DB_XREF=gi:8923612 /UG=Hs.12920 hypothetical protein FLJ20668 /FL=gb:NM_017923.1 NM_017923 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase MARCH1 55016 NM_001166373 /// NM_017923 /// XM_006714247 /// XM_006714248 0000209 // protein polyubiquitination // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002495 // antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006955 // immune response // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219575_s_at NM_022341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022341.1 /DEF=Homo sapiens peptide deformylase-like protein (LOC64146), mRNA. /FEA=mRNA /GEN=LOC64146 /PROD=peptide deformylase-like protein /DB_XREF=gi:11641242 /UG=Hs.130849 peptide deformylase-like protein /FL=gb:AF239156.1 gb:NM_022341.1 gb:AF322879.1 NM_022341 component of oligomeric golgi complex 8 /// peptide deformylase (mitochondrial) COG8 /// PDF 64146 /// 84342 NM_022341 /// NM_032382 0006412 // translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0031365 // N-terminal protein amino acid modification // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // non-traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042586 // peptide deformylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219576_at NM_024765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024765.1 /DEF=Homo sapiens hypothetical protein FLJ12401 (FLJ12401), mRNA. /FEA=mRNA /GEN=FLJ12401 /PROD=hypothetical protein FLJ12401 /DB_XREF=gi:13376106 /UG=Hs.132221 hypothetical protein FLJ12401 /FL=gb:NM_024765.1 NM_024765 MAP7 domain containing 3 MAP7D3 79649 NM_001173516 /// NM_001173517 /// NM_024597 /// NM_024765 /// XM_005262472 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 219577_s_at NM_019112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019112.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7), mRNA. /FEA=mRNA /GEN=ABCA7 /PROD=ATP-binding cassette, sub-family A (ABC1),member 7 /DB_XREF=gi:9506364 /UG=Hs.134514 ATP-binding cassette, sub-family A (ABC1), member 7 /FL=gb:AF328787.1 gb:AF250238.1 gb:NM_019112.1 NM_019112 ATP-binding cassette, sub-family A (ABC1), member 7 ABCA7 10347 NM_019112 /// NM_033308 /// XM_006722616 /// XM_006722617 /// XM_006722618 /// XR_430126 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007613 // memory // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0017121 // phospholipid scrambling // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from sequence or structural similarity /// 0032780 // negative regulation of ATPase activity // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042985 // negative regulation of amyloid precursor protein biosynthetic process // inferred from sequence or structural similarity /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1900223 // positive regulation of beta-amyloid clearance // inferred from sequence or structural similarity /// 1901076 // positive regulation of engulfment of apoptotic cell // inferred from sequence or structural similarity /// 1902430 // negative regulation of beta-amyloid formation // inferred from sequence or structural similarity /// 1902995 // positive regulation of phospholipid efflux // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0001891 // phagocytic cup // inferred from sequence or structural similarity /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0043190 // ATP-binding cassette (ABC) transporter complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005548 // phospholipid transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay 219578_s_at NM_030594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030594.1 /DEF=Homo sapiens hypothetical protein FLJ13203 similar to cytoplasmic polyadenylation element binding protein (CPEB1), mRNA. /FEA=mRNA /GEN=CPEB1 /PROD=cytoplasmic polyadenylation element bindingprotein /DB_XREF=gi:13443003 /UG=Hs.137064 hypothetical protein FLJ13203 similar to cytoplasmic polyadenylation element binding protein /FL=gb:AF329403.1 gb:NM_030594.1 NM_030594 cytoplasmic polyadenylation element binding protein 1 CPEB1 64506 NM_001079533 /// NM_001079534 /// NM_001079535 /// NM_001288819 /// NM_001288820 /// NM_030594 /// XM_006720636 /// XM_006720637 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 2000766 // negative regulation of cytoplasmic translation // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0072687 // meiotic spindle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 219579_at NM_013401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013401.1 /DEF=Homo sapiens RAB3A interacting protein (rabin3)-like 1 (RAB3IL1), mRNA. /FEA=mRNA /GEN=RAB3IL1 /PROD=RAB3A interacting protein (rabin3)-like 1 /DB_XREF=gi:7019512 /UG=Hs.13759 RAB3A interacting protein (rabin3)-like 1 /FL=gb:AF084557.1 gb:NM_013401.1 NM_013401 RAB3A interacting protein (rabin3)-like 1 RAB3IL1 5866 NM_001271686 /// NM_013401 /// XM_005274140 /// XM_006718646 /// XM_006718647 /// XM_006718648 /// XM_006718649 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 219580_s_at NM_024780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024780.1 /DEF=Homo sapiens hypothetical protein FLJ13593 (FLJ13593), mRNA. /FEA=mRNA /GEN=FLJ13593 /PROD=hypothetical protein FLJ13593 /DB_XREF=gi:13376137 /UG=Hs.145807 hypothetical protein FLJ13593 /FL=gb:NM_024780.1 NM_024780 transmembrane channel-like 5 TMC5 79838 NM_001105248 /// NM_001105249 /// NM_001261841 /// NM_024780 /// XM_005255585 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219581_at NM_025265 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025265.1 /DEF=Homo sapiens hypothetical protein MGC2776 (MGC2776), mRNA. /FEA=mRNA /GEN=MGC2776 /PROD=hypothetical protein MGC2776 /DB_XREF=gi:13376881 /UG=Hs.15713 hypothetical protein MGC2776 /FL=gb:BC004178.1 gb:BC004211.1 gb:NM_025265.1 NM_025265 TSEN2 tRNA splicing endonuclease subunit TSEN2 80746 NM_001145392 /// NM_001145393 /// NM_001145394 /// NM_001145395 /// NM_025265 /// XM_005265495 /// XM_005265497 /// XM_005265498 /// XM_005265499 /// XR_245158 /// XR_245159 /// XR_245160 /// XR_427295 /// XR_427296 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0000214 // tRNA-intron endonuclease complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0000213 // tRNA-intron endonuclease activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation 219582_at NM_024576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024576.1 /DEF=Homo sapiens hypothetical protein FLJ21079 (FLJ21079), mRNA. /FEA=mRNA /GEN=FLJ21079 /PROD=hypothetical protein FLJ21079 /DB_XREF=gi:13375751 /UG=Hs.16512 hypothetical protein FLJ21079 /FL=gb:NM_024576.1 NM_024576 opioid growth factor receptor-like 1 OGFRL1 79627 NM_024576 /// XM_005248765 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation 219583_s_at NM_018418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018418.1 /DEF=Homo sapiens hypothetical protein (HSD-3.1), mRNA. /FEA=mRNA /GEN=HSD-3.1 /PROD=hypothetical protein /DB_XREF=gi:13384599 /UG=Hs.177011 hypothetical protein /FL=gb:NM_018418.1 NM_018418 spermatogenesis associated 7 SPATA7 55812 NM_001040428 /// NM_018418 /// XM_005267851 /// XM_005267852 /// XM_005267854 /// XM_005267855 /// XM_006720204 /// XM_006720205 0007601 // visual perception // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 219584_at NM_015900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015900.1 /DEF=Homo sapiens phosphatidylserine-specific phospholipase A1alpha (PS-PLA1), mRNA. /FEA=mRNA /GEN=PS-PLA1 /PROD=phosphatidylserine-specific phospholipaseA1alpha /DB_XREF=gi:7706660 /UG=Hs.17752 phosphatidylserine-specific phospholipase A1alpha /FL=gb:AF035268.1 gb:AF035269.1 gb:U37591.1 gb:NM_015900.1 NM_015900 phospholipase A1 member A PLA1A 51365 NM_001206960 /// NM_001206961 /// NM_001293225 /// NM_015900 /// NR_120610 /// XM_006713653 /// XR_241496 0006629 // lipid metabolic process // traceable author statement /// 0006658 // phosphatidylserine metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008970 // phosphatidylcholine 1-acylhydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 219585_at NM_024296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024296.1 /DEF=Homo sapiens hypothetical protein MGC1203 (MGC1203), mRNA. /FEA=mRNA /GEN=MGC1203 /PROD=hypothetical protein MGC1203 /DB_XREF=gi:13236517 /UG=Hs.17987 hypothetical protein MGC1203 /FL=gb:BC002462.1 gb:NM_024296.1 NM_024296 coiled-coil domain containing 28B CCDC28B 79140 NM_024296 /// XM_006710892 /// XM_006710893 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219586_at NM_030581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030581.1 /DEF=Homo sapiens hypothetical protein MGC11230 (MGC11230), mRNA. /FEA=mRNA /GEN=MGC11230 /PROD=hypothetical protein MGC11230 /DB_XREF=gi:13386493 /UG=Hs.180058 hypothetical protein MGC11230 /FL=gb:BC004519.1 gb:NM_030581.1 NM_030581 WD repeat domain 59 WDR59 79726 NM_030581 /// XM_005256146 /// XM_005256147 219587_at NM_017868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017868.1 /DEF=Homo sapiens hypothetical protein FLJ20535 (FLJ20535), mRNA. /FEA=mRNA /GEN=FLJ20535 /PROD=hypothetical protein FLJ20535 /DB_XREF=gi:8923504 /UG=Hs.183362 hypothetical protein FLJ20535 /FL=gb:NM_017868.1 NM_017868 tetratricopeptide repeat domain 12 TTC12 54970 NM_017868 /// XM_005271603 /// XM_005271604 /// XM_005271605 /// XM_005271606 /// XM_005271607 /// XM_006718866 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219588_s_at NM_017760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017760.1 /DEF=Homo sapiens hypothetical protein FLJ20311 (FLJ20311), mRNA. /FEA=mRNA /GEN=FLJ20311 /PROD=hypothetical protein FLJ20311 /DB_XREF=gi:8923292 /UG=Hs.18616 hypothetical protein FLJ20311 /FL=gb:NM_017760.1 NM_017760 non-SMC condensin II complex, subunit G2 NCAPG2 54892 NM_001281932 /// NM_001281933 /// NM_017760 /// NR_104054 /// XM_005249547 /// XM_006716034 0000278 // mitotic cell cycle // traceable author statement /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 219589_s_at NM_018273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018273.1 /DEF=Homo sapiens hypothetical protein FLJ10922 (FLJ10922), mRNA. /FEA=mRNA /GEN=FLJ10922 /PROD=hypothetical protein FLJ10922 /DB_XREF=gi:8922770 /UG=Hs.19039 hypothetical protein FLJ10922 /FL=gb:NM_018273.1 NM_018273 transmembrane protein 143 TMEM143 55260 NM_018273 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219590_x_at NM_015958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015958.1 /DEF=Homo sapiens CGI-30 protein (LOC51611), mRNA. /FEA=mRNA /GEN=LOC51611 /PROD=CGI-30 protein /DB_XREF=gi:7706271 /UG=Hs.19978 CGI-30 protein /FL=gb:AF132964.1 gb:NM_015958.1 NM_015958 diphthamide biosynthesis 5 DPH5 51611 NM_001077394 /// NM_001077395 /// NM_015958 /// XM_005270938 /// XM_005270939 /// XM_005270941 /// XM_006710683 0008152 // metabolic process // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation 0004164 // diphthine synthase activity // non-traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219591_at NM_016564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016564.1 /DEF=Homo sapiens BM88 antigen (LOC51286), mRNA. /FEA=mRNA /GEN=LOC51286 /PROD=BM88 antigen /DB_XREF=gi:7706096 /UG=Hs.22140 BM88 antigen /FL=gb:AF235030.1 gb:NM_016564.1 NM_016564 cell cycle exit and neuronal differentiation 1 CEND1 51286 NM_016564 0007628 // adult walking behavior // inferred from electronic annotation /// 0021686 // cerebellar granular layer maturation // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0021933 // radial glia guided migration of cerebellar granule cell // inferred from electronic annotation /// 0021941 // negative regulation of cerebellar granule cell precursor proliferation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219592_at NM_024596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024596.1 /DEF=Homo sapiens hypothetical protein FLJ12847 (FLJ12847), mRNA. /FEA=mRNA /GEN=FLJ12847 /PROD=hypothetical protein FLJ12847 /DB_XREF=gi:13375792 /UG=Hs.23782 hypothetical protein FLJ12847 /FL=gb:NM_024596.1 NM_024596 microcephalin 1 MCPH1 79648 NM_001172574 /// NM_001172575 /// NM_024596 /// XM_005266034 /// XM_005266035 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0043549 // regulation of kinase activity // inferred from electronic annotation /// 0046605 // regulation of centrosome cycle // inferred from electronic annotation /// 0060623 // regulation of chromosome condensation // inferred from electronic annotation /// 0071539 // protein localization to centrosome // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 219593_at NM_016582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016582.1 /DEF=Homo sapiens peptide transporter 3 (LOC51296), mRNA. /FEA=mRNA /GEN=LOC51296 /PROD=peptide transporter 3 /DB_XREF=gi:7706116 /UG=Hs.237856 peptide transporter 3 /FL=gb:AB020598.1 gb:NM_016582.1 NM_016582 solute carrier family 15 (oligopeptide transporter), member 3 SLC15A3 51296 NM_016582 /// NR_027391 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 219594_at NM_016533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016533.1 /DEF=Homo sapiens ninjurin 2 (NINJ2), mRNA. /FEA=mRNA /GEN=NINJ2 /PROD=ninjurin 2 /DB_XREF=gi:7706622 /UG=Hs.239208 ninjurin 2 /FL=gb:AF205633.1 gb:NM_016533.1 NM_016533 ninjurin 2 NINJ2 4815 NM_001294345 /// NM_001294346 /// NM_016533 /// XM_005253689 /// XM_006718984 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219595_at NM_019591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019591.1 /DEF=Homo sapiens zinc finger protein 26 (KOX 20) (ZNF26), mRNA. /FEA=mRNA /GEN=ZNF26 /PROD=hypothetical protein FLJ20755 /DB_XREF=gi:11034838 /UG=Hs.26432 zinc finger protein 26 (KOX 20) /FL=gb:NM_019591.1 NM_019591 zinc finger protein 26 ZNF26 7574 NM_001256279 /// NM_001256280 /// NM_019591 /// XM_005266182 /// XM_005266183 /// XM_006719744 /// XM_006719745 /// XM_006719746 /// XR_429210 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219596_at NM_020147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020147.1 /DEF=Homo sapiens hypothetical protein from EUROIMAGE 511235 (LOC56906), mRNA. /FEA=mRNA /GEN=LOC56906 /PROD=hypothetical protein from EUROIMAGE 511235 /DB_XREF=gi:9910353 /UG=Hs.26815 hypothetical protein from EUROIMAGE 511235 /FL=gb:NM_020147.1 NM_020147 THAP domain containing 10 THAP10 56906 NM_020147 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219597_s_at NM_017434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017434.1 /DEF=Homo sapiens dual oxidase 1 (DUOX1), mRNA. /FEA=mRNA /GEN=DUOX1 /PROD=dual oxidase 1 /DB_XREF=gi:8393276 /UG=Hs.272813 dual oxidase 1 /FL=gb:AF213465.1 gb:NM_017434.1 NM_017434 dual oxidase 1 DUOX1 53905 NM_017434 /// NM_175940 /// XM_005254463 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0042335 // cuticle development // inferred from mutant phenotype /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0042554 // superoxide anion generation // non-traceable author statement /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // non-traceable author statement /// 0051591 // response to cAMP // inferred from direct assay /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // non-traceable author statement 0004601 // peroxidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016174 // NAD(P)H oxidase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // non-traceable author statement 219598_s_at NM_016104 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016104.1 /DEF=Homo sapiens PTD013 protein (PTD013), mRNA. /FEA=mRNA /GEN=PTD013 /PROD=PTD013 protein /DB_XREF=gi:7706668 /UG=Hs.279857 PTD013 protein /FL=gb:AF092134.1 gb:NM_016104.1 NM_016104 RWD domain containing 1 RWDD1 51389 NM_001007464 /// NM_015952 /// NM_016104 0005515 // protein binding // inferred from physical interaction 219599_at NM_018507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018507.1 /DEF=Homo sapiens hypothetical protein PRO1843 (PRO1843), mRNA. /FEA=mRNA /GEN=PRO1843 /PROD=hypothetical protein PRO1843 /DB_XREF=gi:8924082 /UG=Hs.283330 hypothetical protein PRO1843 /FL=gb:AF119854.1 gb:NM_018507.1 NM_018507 eukaryotic translation initiation factor 4B EIF4B 1975 NM_001417 /// NM_018507 /// XM_005268709 /// XM_006719274 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219600_s_at NM_006134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006134.2 /DEF=Homo sapiens chromosome 21 open reading frame 4 (C21ORF4), mRNA. /FEA=mRNA /GEN=C21ORF4 /PROD=chromosome 21 open reading frame 4 /DB_XREF=gi:8659558 /UG=Hs.284142 chromosome 21 open reading frame 4 /FL=gb:BC000569.1 gb:AF045606.2 gb:NM_006134.2 NM_006134 transmembrane protein 50B TMEM50B 757 NM_006134 /// NR_038211 /// NR_040016 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219601_s_at NM_015652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015652.1 /DEF=Homo sapiens DKFZP564P1916 protein (DKFZP564P1916), mRNA. /FEA=mRNA /GEN=DKFZP564P1916 /PROD=DKFZP564P1916 protein /DB_XREF=gi:13435130 /UG=Hs.285391 DKFZP564P1916 protein /FL=gb:NM_015652.1 NM_015652 chromosome 10 open reading frame 12 C10orf12 26148 NM_015652 219602_s_at NM_022068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022068.1 /DEF=Homo sapiens hypothetical protein FLJ23403 (FLJ23403), mRNA. /FEA=mRNA /GEN=FLJ23403 /PROD=hypothetical protein FLJ23403 /DB_XREF=gi:13384601 /UG=Hs.293907 hypothetical protein FLJ23403 /FL=gb:NM_022068.1 NM_022068 piezo-type mechanosensitive ion channel component 2 PIEZO2 63895 NM_022068 /// NM_173817 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050974 // detection of mechanical stimulus involved in sensory perception // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005261 // cation channel activity // inferred from electronic annotation /// 0008381 // mechanically-gated ion channel activity // inferred from electronic annotation 219603_s_at NM_015919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015919.1 /DEF=Homo sapiens Kruppel-associated box protein (LOC51595), mRNA. /FEA=mRNA /GEN=LOC51595 /PROD=Kruppel-associated box protein /DB_XREF=gi:7706241 /UG=Hs.30303 Kruppel-associated box protein /FL=gb:AF070666.1 gb:NM_015919.1 NM_015919 zinc finger protein 226 ZNF226 7769 NM_001032372 /// NM_001032373 /// NM_001032374 /// NM_001032375 /// NM_001146220 /// NM_015919 /// NM_016444 /// XM_005259224 /// XM_005259225 /// XM_005259226 /// XM_005259227 /// XM_005259228 /// XM_006723367 /// XM_006723368 /// XM_006723369 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219604_s_at NM_017715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017715.1 /DEF=Homo sapiens hypothetical protein FLJ20216 (FLJ20216), mRNA. /FEA=mRNA /GEN=FLJ20216 /PROD=hypothetical protein FLJ20216 /DB_XREF=gi:8923203 /UG=Hs.313765 hypothetical protein FLJ20216 /FL=gb:NM_017715.1 NM_017715 zinc finger protein 3 ZNF3 7551 NM_001278284 /// NM_001278287 /// NM_001278290 /// NM_001278291 /// NM_001278292 /// NM_017715 /// NM_032924 /// XM_006716110 /// XM_006716111 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045321 // leukocyte activation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219605_at NM_017715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017715.1 /DEF=Homo sapiens hypothetical protein FLJ20216 (FLJ20216), mRNA. /FEA=mRNA /GEN=FLJ20216 /PROD=hypothetical protein FLJ20216 /DB_XREF=gi:8923203 /UG=Hs.313765 hypothetical protein FLJ20216 /FL=gb:NM_017715.1 NM_017715 zinc finger protein 3 ZNF3 7551 NM_001278284 /// NM_001278287 /// NM_001278290 /// NM_001278291 /// NM_001278292 /// NM_017715 /// NM_032924 /// XM_006716110 /// XM_006716111 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045321 // leukocyte activation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219606_at NM_016018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016018.1 /DEF=Homo sapiens CGI-72 protein (LOC51105), mRNA. /FEA=mRNA /GEN=LOC51105 /PROD=CGI-72 protein /DB_XREF=gi:7705782 /UG=Hs.318725 CGI-72 protein /FL=gb:AF151830.1 gb:NM_016018.1 NM_016018 PHD finger protein 20-like 1 PHF20L1 51105 NM_001277196 /// NM_016018 /// NM_024878 /// NM_032205 /// NM_198513 /// XM_005250930 /// XM_005250931 /// XM_005250932 /// XM_005250933 /// XM_005250934 /// XM_005250935 /// XM_005250936 /// XM_005250937 /// XM_005250938 /// XM_005250939 /// XM_005250940 /// XM_005250942 /// XM_006716572 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219607_s_at NM_024021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024021.1 /DEF=Homo sapiens membrane-spanning 4-domains, subfamily A, member 4 (MS4A4), mRNA. /FEA=mRNA /GEN=MS4A4 /PROD=membrane-spanning 4-domains, subfamily A, member4 /DB_XREF=gi:13430865 /UG=Hs.325960 membrane-spanning 4-domains, subfamily A, member 4 /FL=gb:AB013102.1 gb:NM_024021.1 gb:AF068288.1 gb:NM_016650.1 NM_024021 membrane-spanning 4-domains, subfamily A, member 4A MS4A4A 51338 NM_001243266 /// NM_024021 /// NM_148975 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219608_s_at NM_024862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024862.1 /DEF=Homo sapiens hypothetical protein FLJ13962 (FLJ13962), mRNA. /FEA=mRNA /GEN=FLJ13962 /PROD=hypothetical protein FLJ13962 /DB_XREF=gi:13376291 /UG=Hs.330407 hypothetical protein FLJ13962 /FL=gb:NM_024862.1 NM_024862 F-box protein 38 FBXO38 81545 NM_001271723 /// NM_030793 /// NM_205836 /// XM_005268513 /// XM_006714796 /// XM_006714797 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219609_at NM_024515 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024515.1 /DEF=Homo sapiens hypothetical protein MGC4645 (MGC4645), mRNA. /FEA=mRNA /GEN=MGC4645 /PROD=hypothetical protein MGC4645 /DB_XREF=gi:13375651 /UG=Hs.332381 hypothetical protein MGC4645 /FL=gb:BC003641.1 gb:NM_024515.1 NM_024515 WD repeat domain 25 WDR25 79446 NM_001161476 /// NM_024515 /// XM_005268056 /// XM_005268057 /// XM_005268058 0005515 // protein binding // inferred from electronic annotation 219610_at NM_022448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022448.1 /DEF=Homo sapiens hypothetical protein FLJ21817 similar to Rhoip2 (FLJ21817), mRNA. /FEA=mRNA /GEN=FLJ21817 /PROD=hypothetical protein FLJ21817 similar to Rhoip2 /DB_XREF=gi:11967978 /UG=Hs.33254 hypothetical protein FLJ21817 similar to Rhoip2 /FL=gb:NM_022448.1 NM_022448 Rho guanine nucleotide exchange factor (GEF) 28 ARHGEF28 64283 NM_001080479 /// NM_001177693 /// NM_001244364 /// XM_005248568 /// XM_006714669 0021955 // central nervous system neuron axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219611_s_at NM_022778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022778.1 /DEF=Homo sapiens hypothetical protein DKFZp434L0117 (DKFZP434L0117), mRNA. /FEA=mRNA /GEN=DKFZP434L0117 /PROD=hypothetical protein DKFZp434L0117 /DB_XREF=gi:12232464 /UG=Hs.63795 hypothetical protein DKFZp434L0117 /FL=gb:NM_022778.1 NM_022778 centrosomal protein 85kDa CEP85 64793 NM_001281517 /// NM_001281518 /// NM_022778 /// XM_005245969 /// XM_006710822 /// XM_006710823 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219612_s_at NM_000509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000509.3 /DEF=Homo sapiens fibrinogen, gamma polypeptide (FGG), transcript variant gamma-A, mRNA. /FEA=mRNA /GEN=FGG /PROD=fibrinogen, gamma chain, isoform gamma-Aprecursor /DB_XREF=gi:11761634 /UG=Hs.75431 fibrinogen, gamma polypeptide /FL=gb:NM_000509.3 gb:AF118092.1 NM_000509 fibrinogen gamma chain FGG 2266 NM_000509 /// NM_021870 0002576 // platelet degranulation // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from direct assay /// 0045921 // positive regulation of exocytosis // inferred from direct assay /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051258 // protein polymerization // inferred from mutant phenotype /// 0051592 // response to calcium ion // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // inferred from direct assay /// 0090277 // positive regulation of peptide hormone secretion // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005198 // structural molecule activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 219613_s_at NM_016539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016539.1 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6 (SIRT6), mRNA. /FEA=mRNA /GEN=SIRT6 /PROD=sirtuin 6 /DB_XREF=gi:7706709 /UG=Hs.105463 sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6 /FL=gb:BC005026.1 gb:AF233396.1 gb:NM_016539.1 NM_016539 sirtuin 6 SIRT6 51548 NM_001193285 /// NM_016539 /// XM_005259574 /// XM_005259575 /// XM_005259577 /// XM_006722767 0006471 // protein ADP-ribosylation // inferred from sequence or structural similarity /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005724 // nuclear telomeric heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0003956 // NAD(P)+-protein-arginine ADP-ribosyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017136 // NAD-dependent histone deacetylase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from direct assay /// 0070403 // NAD+ binding // inferred from sequence or structural similarity 219614_s_at NM_020208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020208.1 /DEF=Homo sapiens X transporter protein 3 (XT3), transcript variant 1, mRNA. /FEA=mRNA /GEN=XT3 /PROD=X transporter protein 3, isoform 1 /DB_XREF=gi:11181769 /UG=Hs.107854 X transporter protein 3 /FL=gb:NM_020208.1 NM_020208 solute carrier family 6 (proline IMINO transporter), member 20 SLC6A20 54716 NM_020208 /// NM_022405 /// XM_005265236 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0015816 // glycine transport // inferred from mutant phenotype /// 0015824 // proline transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation 219615_s_at NM_003740 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003740.1 /DEF=Homo sapiens potassium channel, subfamily K, member 5 (TASK-2) (KCNK5), mRNA. /FEA=mRNA /GEN=KCNK5 /PROD=potassium channel, subfamily K, member 5(TASK-2) /DB_XREF=gi:4504850 /UG=Hs.127007 potassium channel, subfamily K, member 5 (TASK-2) /FL=gb:AF084830.1 gb:NM_003740.1 NM_003740 potassium channel, subfamily K, member 5 KCNK5 8645 NM_003740 /// XM_005249456 /// XM_006715235 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 219616_at NM_024560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024560.1 /DEF=Homo sapiens hypothetical protein FLJ21963 (FLJ21963), mRNA. /FEA=mRNA /GEN=FLJ21963 /PROD=hypothetical protein FLJ21963 /DB_XREF=gi:13375726 /UG=Hs.13222 hypothetical protein FLJ21963 /FL=gb:NM_024560.1 NM_024560 acyl-CoA synthetase short-chain family member 3 ACSS3 79611 NM_024560 /// XM_005269150 /// XM_005269151 /// XM_006719601 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003987 // acetate-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 219617_at NM_024766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024766.1 /DEF=Homo sapiens hypothetical protein FLJ23451 (FLJ23451), mRNA. /FEA=mRNA /GEN=FLJ23451 /PROD=hypothetical protein FLJ23451 /DB_XREF=gi:13376108 /UG=Hs.132799 hypothetical protein FLJ23451 /FL=gb:NM_024766.1 NM_024766 calmodulin-lysine N-methyltransferase CAMKMT 79823 NM_024766 /// XM_005264567 0018022 // peptidyl-lysine methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018025 // calmodulin-lysine N-methyltransferase activity // inferred from electronic annotation 219618_at NM_016123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016123.1 /DEF=Homo sapiens putative protein kinase NY-REN-64 antigen (LOC51135), mRNA. /FEA=mRNA /GEN=LOC51135 /PROD=putative protein kinase NY-REN-64 antigen /DB_XREF=gi:7705840 /UG=Hs.142295 putative protein kinase NY-REN-64 antigen /FL=gb:AF155118.1 gb:NM_016123.1 NM_016123 interleukin-1 receptor-associated kinase 4 IRAK4 51135 NM_001114182 /// NM_001145256 /// NM_001145257 /// NM_001145258 /// NM_016123 /// XM_005268943 /// XM_005268944 /// XM_005268945 /// XM_005268946 /// XM_005268947 /// XM_005268948 /// XM_005268949 /// XM_006719438 /// XM_006719439 /// XM_006719440 /// XM_006719441 /// XM_006719442 /// XM_006719443 0001816 // cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 219619_at NM_017594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017594.1 /DEF=Homo sapiens hypothetical protein DKFZp761C07121 (DKFZp761C07121), mRNA. /FEA=mRNA /GEN=DKFZp761C07121 /PROD=hypothetical protein DKFZp761C07121 /DB_XREF=gi:8922160 /UG=Hs.165636 hypothetical protein DKFZp761C07121 /FL=gb:NM_017594.1 NM_017594 DIRAS family, GTP-binding RAS-like 2 DIRAS2 54769 NM_017594 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction 219620_x_at NM_017723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017723.1 /DEF=Homo sapiens hypothetical protein FLJ20245 (FLJ20245), mRNA. /FEA=mRNA /GEN=FLJ20245 /PROD=hypothetical protein FLJ20245 /DB_XREF=gi:8923220 /UG=Hs.169758 hypothetical protein FLJ20245 /FL=gb:NM_017723.1 NM_017723 torsin family 4, member A TOR4A 54863 NM_017723 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 219621_at NM_022111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022111.1 /DEF=Homo sapiens homolog of Xenopus Claspin (CLASPIN), mRNA. /FEA=mRNA /GEN=CLASPIN /PROD=homolog of Xenopus Claspin /DB_XREF=gi:11545824 /UG=Hs.175613 homolog of Xenopus Claspin /FL=gb:AF297866.1 gb:NM_022111.1 NM_022111 claspin CLSPN 63967 NM_001190481 /// NM_022111 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0033314 // mitotic DNA replication checkpoint // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction 219622_at NM_017817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017817.1 /DEF=Homo sapiens hypothetical protein FLJ20429 (FLJ20429), mRNA. /FEA=mRNA /GEN=FLJ20429 /PROD=hypothetical protein FLJ20429 /DB_XREF=gi:8923400 /UG=Hs.179791 hypothetical protein FLJ20429 /FL=gb:NM_017817.1 NM_017817 RAB20, member RAS oncogene family RAB20 55647 NM_017817 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0090383 // phagosome acidification // inferred from mutant phenotype /// 0090385 // phagosome-lysosome fusion // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219623_at NM_024855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024855.1 /DEF=Homo sapiens hypothetical protein FLJ12785 (FLJ12785), mRNA. /FEA=mRNA /GEN=FLJ12785 /PROD=hypothetical protein FLJ12785 /DB_XREF=gi:13376281 /UG=Hs.192742 hypothetical protein FLJ12785 /FL=gb:NM_024855.1 NM_024855 ARP5 actin-related protein 5 homolog (yeast) ACTR5 79913 NM_024855 /// XM_005260554 /// XM_005260555 /// XM_005260556 /// XM_005260557 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219624_at NM_004874 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004874.1 /DEF=Homo sapiens BCL2-associated athanogene 4 (BAG4), mRNA. /FEA=mRNA /GEN=BAG4 /PROD=BCL2-associated athanogene 4 /DB_XREF=gi:6631074 /UG=Hs.194726 BCL2-associated athanogene 4 /FL=gb:AF111116.1 gb:AF095194.2 gb:NM_004874.1 NM_004874 BCL2-associated athanogene 4 BAG4 9530 NM_001204878 /// NM_004874 0006457 // protein folding // traceable author statement /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090367 // negative regulation of mRNA modification // inferred from electronic annotation /// 0097178 // ruffle assembly // inferred from electronic annotation /// 2001145 // negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005057 // receptor signaling protein activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 219625_s_at NM_005713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005713.1 /DEF=Homo sapiens collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), mRNA. /FEA=mRNA /GEN=COL4A3BP /PROD=collagen, type IV, alpha 3 (Goodpasture antigen)binding protein /DB_XREF=gi:5031716 /UG=Hs.21276 collagen, type IV, alpha 3 (Goodpasture antigen) binding protein /FL=gb:AF136450.1 gb:NM_005713.1 NM_005713 collagen, type IV, alpha 3 (Goodpasture antigen) binding protein COL4A3BP 10087 NM_001130105 /// NM_005713 /// NM_031361 /// XM_006714513 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006672 // ceramide metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0035621 // ER to Golgi ceramide transport // inferred from genetic interaction /// 0035621 // ER to Golgi ceramide transport // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004672 // protein kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0035620 // ceramide transporter activity // inferred from direct assay /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay /// 0097001 // ceramide binding // inferred from direct assay 219626_at NM_024597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024597.1 /DEF=Homo sapiens hypothetical protein FLJ12649 (FLJ12649), mRNA. /FEA=mRNA /GEN=FLJ12649 /PROD=hypothetical protein FLJ12649 /DB_XREF=gi:13375794 /UG=Hs.24078 hypothetical protein FLJ12649 /FL=gb:NM_024597.1 NM_024597 MAP7 domain containing 3 MAP7D3 79649 NM_001173516 /// NM_001173517 /// NM_024597 /// NM_024765 /// XM_005262472 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 219627_at NM_024910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024910.1 /DEF=Homo sapiens hypothetical protein FLJ12700 (FLJ12700), mRNA. /FEA=mRNA /GEN=FLJ12700 /PROD=hypothetical protein FLJ12700 /DB_XREF=gi:13376370 /UG=Hs.250547 hypothetical protein FLJ12700 /FL=gb:NM_024910.1 NM_024910 zinc finger family member 767, pseudogene ZNF767P 79970 NM_024910 /// NR_027788 /// NR_027789 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 219628_at NM_022470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022470.1 /DEF=Homo sapiens hypothetical protein FLJ12296 similar to wild-type p53-induced gene 1 (FLJ12296), mRNA. /FEA=mRNA /GEN=FLJ12296 /PROD=hypothetical protein FLJ12296 similar towild-type p53-induced gene 1 /DB_XREF=gi:11968018 /UG=Hs.252406 hypothetical protein FLJ12296 similar to wild-type p53-induced gene 1 /FL=gb:NM_022470.1 gb:BC002896.1 NM_022470 zinc finger, matrin-type 3 ZMAT3 64393 NM_022470 /// NM_152240 /// XM_005247706 /// XM_006713725 /// XM_006713726 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219629_at NM_017911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017911.1 /DEF=Homo sapiens hypothetical protein FLJ20635 (FLJ20635), mRNA. /FEA=mRNA /GEN=FLJ20635 /PROD=hypothetical protein FLJ20635 /DB_XREF=gi:8923587 /UG=Hs.265018 hypothetical protein FLJ20635 /FL=gb:NM_017911.1 NM_017911 family with sequence similarity 118, member A FAM118A 55007 NM_001104595 /// NM_017911 /// XM_005261665 /// XM_005261666 /// XM_006724272 /// XM_006724273 /// XM_006724274 /// XM_006724275 /// XM_006724276 /// XM_006724277 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 219630_at NM_005764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005764.1 /DEF=Homo sapiens epithelial protein up-regulated in carcinoma, membrane associated protein 17 (DD96), mRNA. /FEA=mRNA /GEN=DD96 /PROD=epithelial protein up-regulated in carcinoma,membrane associated protein 17 /DB_XREF=gi:5031656 /UG=Hs.271473 epithelial protein up-regulated in carcinoma, membrane associated protein 17 /FL=gb:NM_005764.1 NM_005764 PDZK1 interacting protein 1 PDZK1IP1 10158 NM_005764 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 219631_at NM_024937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024937.1 /DEF=Homo sapiens hypothetical protein FLJ12929 (FLJ12929), mRNA. /FEA=mRNA /GEN=FLJ12929 /PROD=hypothetical protein FLJ12929 /DB_XREF=gi:13376412 /UG=Hs.278956 hypothetical protein FLJ12929 /FL=gb:NM_024937.1 NM_024937 low density lipoprotein receptor-related protein 12 LRP12 29967 NM_001135703 /// NM_013437 0006897 // endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005041 // low-density lipoprotein receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219632_s_at AF196175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF196175.1 /DEF=Homo sapiens capsaicin receptor mRNA, complete cds. /FEA=mRNA /PROD=capsaicin receptor /DB_XREF=gi:12003145 /UG=Hs.283010 vanilloid receptor subtype 1 /FL=gb:AF196175.1 gb:NM_018727.1 AF196175 sedoheptulokinase /// transient receptor potential cation channel, subfamily V, member 1 SHPK /// TRPV1 7442 /// 23729 NM_013276 /// NM_018727 /// NM_080704 /// NM_080705 /// NM_080706 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007635 // chemosensory behavior // traceable author statement /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035963 // cellular response to interleukin-13 // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050955 // thermoception // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071312 // cellular response to alkaloid // inferred from sequence or structural similarity /// 0071318 // cellular response to ATP // inferred from sequence or structural similarity /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005231 // excitatory extracellular ligand-gated ion channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0015278 // calcium-release channel activity // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0050277 // sedoheptulokinase activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 219633_at NM_024331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024331.1 /DEF=Homo sapiens hypothetical protein MGC2470 (MGC2470), mRNA. /FEA=mRNA /GEN=MGC2470 /PROD=hypothetical protein MGC2470 /DB_XREF=gi:13236580 /UG=Hs.283869 hypothetical protein MGC2470 /FL=gb:BC003071.1 gb:NM_024331.1 NM_024331 tocopherol (alpha) transfer protein-like TTPAL 79183 NM_001039199 /// NM_001261839 /// NM_024331 /// XM_005260549 0006810 // transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 219634_at NM_018413 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018413.1 /DEF=Homo sapiens chondroitin 4-sulfotransferase (C4ST), mRNA. /FEA=mRNA /GEN=C4ST /PROD=chondroitin 4-sulfotransferase /DB_XREF=gi:8923757 /UG=Hs.287402 chondroitin 4-sulfotransferase /FL=gb:AB042326.1 gb:NM_018413.1 gb:AF239820.1 NM_018413 carbohydrate (chondroitin 4) sulfotransferase 11 CHST11 50515 NM_001173982 /// NM_018413 0002063 // chondrocyte development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0033037 // polysaccharide localization // inferred from electronic annotation /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001537 // N-acetylgalactosamine 4-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047756 // chondroitin 4-sulfotransferase activity // inferred from direct assay /// 0050659 // N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity // inferred from electronic annotation 219635_at NM_025027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025027.1 /DEF=Homo sapiens hypothetical protein FLJ14260 (FLJ14260), mRNA. /FEA=mRNA /GEN=FLJ14260 /PROD=hypothetical protein FLJ14260 /DB_XREF=gi:13430885 /UG=Hs.287629 hypothetical protein FLJ14260 /FL=gb:NM_025027.1 NM_025027 zinc finger protein 606 ZNF606 80095 NM_025027 /// XM_005259276 /// XM_005259277 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219636_s_at NM_025139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025139.1 /DEF=Homo sapiens hypothetical protein FLJ12584 (FLJ12584), mRNA. /FEA=mRNA /GEN=FLJ12584 /PROD=hypothetical protein FLJ12584 /DB_XREF=gi:13376722 /UG=Hs.288897 hypothetical protein FLJ12584 /FL=gb:BC004514.1 gb:NM_025139.1 NM_025139 armadillo repeat containing 9 ARMC9 80210 NM_001271466 /// NM_001291656 /// NM_025139 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219637_at NM_025139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025139.1 /DEF=Homo sapiens hypothetical protein FLJ12584 (FLJ12584), mRNA. /FEA=mRNA /GEN=FLJ12584 /PROD=hypothetical protein FLJ12584 /DB_XREF=gi:13376722 /UG=Hs.288897 hypothetical protein FLJ12584 /FL=gb:BC004514.1 gb:NM_025139.1 NM_025139 armadillo repeat containing 9 ARMC9 80210 NM_001271466 /// NM_001291656 /// NM_025139 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219638_at NM_012170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012170.1 /DEF=Homo sapiens F-box only protein 22 (FBXO22), mRNA. /FEA=mRNA /GEN=FBXO22 /PROD=F-box only protein 22 /DB_XREF=gi:13442999 /UG=Hs.289074 F-box only protein 22 /FL=gb:NM_012170.1 NM_012170 F-box protein 22 FBXO22 26263 NM_012170 /// NM_147188 /// NR_037623 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0048742 // regulation of skeletal muscle fiber development // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219639_x_at NM_020213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020213.1 /DEF=Homo sapiens hypothetical protein from EUROIMAGE 1977056 (LOC56965), mRNA. /FEA=mRNA /GEN=LOC56965 /PROD=hypothetical protein from EUROIMAGE 1977056 /DB_XREF=gi:9910373 /UG=Hs.315687 hypothetical protein from EUROIMAGE 1977056 /FL=gb:NM_020213.1 NM_020213 poly (ADP-ribose) polymerase family, member 6 PARP6 56965 NM_020213 /// NM_020214 /// XM_005254557 /// XM_005254558 /// XM_005254559 /// XR_243112 /// XR_243113 /// XR_243114 /// XR_243115 /// XR_243116 /// XR_429467 0008152 // metabolic process // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 219640_at NM_014343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014343.1 /DEF=Homo sapiens claudin 15 (CLDN15), mRNA. /FEA=mRNA /GEN=CLDN15 /PROD=claudin 15 /DB_XREF=gi:7656980 /UG=Hs.38738 claudin 15 /FL=gb:NM_014343.1 NM_014343 claudin 15 CLDN15 24146 NM_001185080 /// NM_014343 /// NM_138429 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 219641_at NM_017996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017996.1 /DEF=Homo sapiens hypothetical protein FLJ10103 (FLJ10103), mRNA. /FEA=mRNA /GEN=FLJ10103 /PROD=hypothetical protein FLJ10103 /DB_XREF=gi:8922230 /UG=Hs.42140 hypothetical protein FLJ10103 /FL=gb:BC001242.1 gb:NM_017996.1 NM_017996 de-etiolated homolog 1 (Arabidopsis) DET1 55070 NM_001144074 /// NM_017996 /// NR_026645 /// XM_006720597 /// XM_006720598 /// XM_006720599 /// XR_429461 0005634 // nucleus // inferred from electronic annotation 219642_s_at NM_016559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016559.1 /DEF=Homo sapiens PXR2b protein (PXR2b), mRNA. /FEA=mRNA /GEN=PXR2b /PROD=PXR2b protein /DB_XREF=gi:7706670 /UG=Hs.46780 PXR2b protein /FL=gb:AB032593.1 gb:NM_016559.1 NM_016559 peroxisomal biogenesis factor 5-like PEX5L 51555 NM_001256750 /// NM_001256751 /// NM_001256752 /// NM_001256753 /// NM_001256754 /// NM_001256755 /// NM_001256756 /// NM_016559 /// XM_005247524 /// XM_005247526 /// XM_006713656 0016558 // protein import into peroxisome matrix // not recorded /// 0016560 // protein import into peroxisome matrix, docking // not recorded /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from sequence or structural similarity /// 0045185 // maintenance of protein location // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // not recorded /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // not recorded /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from physical interaction 219643_at NM_018557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018557.1 /DEF=Homo sapiens low density lipoprotein-related protein 1B (deleted in tumors) (LRP1B), mRNA. /FEA=mRNA /GEN=LRP1B /PROD=low density lipoprotein-related protein 1B(deleted in tumors) /DB_XREF=gi:9055269 /UG=Hs.47005 low density lipoprotein-related protein 1B (deleted in tumors) /FL=gb:AF176832.1 gb:NM_018557.1 NM_018557 low density lipoprotein receptor-related protein 1B LRP1B 53353 NM_018557 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0015031 // protein transport // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005041 // low-density lipoprotein receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219644_at NM_016122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016122.1 /DEF=Homo sapiens NY-REN-58 antigen (LOC51134), mRNA. /FEA=mRNA /GEN=LOC51134 /PROD=NY-REN-58 antigen /DB_XREF=gi:7705838 /UG=Hs.56148 NY-REN-58 antigen /FL=gb:AF155115.1 gb:NM_016122.1 NM_016122 centrosomal protein 83kDa CEP83 51134 NM_001042399 /// NM_016122 /// XM_005268942 /// XM_006719437 /// XR_429106 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0048278 // vesicle docking // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0097539 // ciliary transition fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219645_at NM_001231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001231.1 /DEF=Homo sapiens calsequestrin 1 (fast-twitch, skeletal muscle) (CASQ1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CASQ1 /PROD=skeletal muscle calsequestrin 1 /DB_XREF=gi:4557406 /UG=Hs.60708 calsequestrin 1 (fast-twitch, skeletal muscle) /FL=gb:NM_001231.1 gb:S73775.1 NM_001231 calsequestrin 1 (fast-twitch, skeletal muscle) CASQ1 844 NM_001231 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from electronic annotation /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred from electronic annotation /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0051282 // regulation of sequestering of calcium ion // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005790 // smooth endoplasmic reticulum // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0014802 // terminal cisterna // inferred from electronic annotation /// 0014804 // terminal cisterna lumen // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 219646_at NM_017702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017702.1 /DEF=Homo sapiens hypothetical protein FLJ20186 (FLJ20186), mRNA. /FEA=mRNA /GEN=FLJ20186 /PROD=hypothetical protein FLJ20186 /DB_XREF=gi:8923176 /UG=Hs.65021 hypothetical protein FLJ20186 /FL=gb:NM_017702.1 NM_017702 differentially expressed in FDCP 8 homolog (mouse) DEF8 54849 NM_001242816 /// NM_001242817 /// NM_001242818 /// NM_001242819 /// NM_001242820 /// NM_001242821 /// NM_001242822 /// NM_017702 /// NM_207514 /// XM_005256316 /// XM_005256318 /// XM_006721207 /// XM_006721208 /// XM_006721209 /// XM_006721210 0035556 // intracellular signal transduction // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219647_at NM_022135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022135.1 /DEF=Homo sapiens popeye protein 2 (POP2), mRNA. /FEA=mRNA /GEN=POP2 /PROD=popeye protein 2 /DB_XREF=gi:11545868 /UG=Hs.77208 popeye protein 2 /FL=gb:AF204173.1 gb:NM_022135.1 NM_022135 popeye domain containing 2 POPDC2 64091 NM_022135 /// XM_005247698 /// XM_005247699 /// XR_241504 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 219648_at NM_018000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018000.1 /DEF=Homo sapiens hypothetical protein FLJ10116 (FLJ10116), mRNA. /FEA=mRNA /GEN=FLJ10116 /PROD=hypothetical protein FLJ10116 /DB_XREF=gi:8922236 /UG=Hs.79741 hypothetical protein FLJ10116 /FL=gb:NM_018000.1 NM_018000 melanoregulin MREG 55686 NM_018000 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 219649_at NM_013339 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013339.1 /DEF=Homo sapiens dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase (ALG6), mRNA. /FEA=mRNA /GEN=ALG6 /PROD=dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase /DB_XREF=gi:7019324 /UG=Hs.80042 dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase /FL=gb:AF063604.1 gb:BC001253.1 gb:AF102851.1 gb:NM_013339.1 NM_013339 ALG6, alpha-1,3-glucosyltransferase ALG6 29929 NM_013339 /// XM_005270788 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0006487 // protein N-linked glycosylation // inferred from genetic interaction /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046527 // glucosyltransferase activity // inferred from direct assay 219650_at NM_017669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017669.1 /DEF=Homo sapiens hypothetical protein FLJ20105 (FLJ20105), mRNA. /FEA=mRNA /GEN=FLJ20105 /PROD=hypothetical protein FLJ20105 /DB_XREF=gi:8923111 /UG=Hs.89306 hypothetical protein FLJ20105 /FL=gb:NM_017669.1 NM_017669 excision repair cross-complementation group 6-like ERCC6L 54821 NM_001009954 /// NM_017669 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219651_at NM_018189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018189.1 /DEF=Homo sapiens hypothetical protein FLJ10713 (FLJ10713), mRNA. /FEA=mRNA /GEN=FLJ10713 /PROD=hypothetical protein FLJ10713 /DB_XREF=gi:8922611 /UG=Hs.9536 hypothetical protein FLJ10713 /FL=gb:NM_018189.1 NM_018189 developmental pluripotency associated 4 DPPA4 55211 NM_018189 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219652_s_at NM_024689 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024689.1 /DEF=Homo sapiens hypothetical protein FLJ14103 (FLJ14103), mRNA. /FEA=mRNA /GEN=FLJ14103 /PROD=hypothetical protein FLJ14103 /DB_XREF=gi:13375963 /UG=Hs.98321 hypothetical protein FLJ14103 /FL=gb:NM_024689.1 NM_024689 chromosome X open reading frame 36 CXorf36 79742 NM_024689 /// NM_176819 /// XM_005272670 /// XM_006724559 0005576 // extracellular region // inferred from electronic annotation 219653_at NM_014054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014054.1 /DEF=Homo sapiens FT005 protein (FT005), mRNA. /FEA=mRNA /GEN=FT005 /PROD=FT005 protein /DB_XREF=gi:7661709 /UG=Hs.105379 FT005 protein /FL=gb:AF165185.1 gb:NM_014054.1 NM_014054 LSM14B, SCD6 homolog B (S. cerevisiae) LSM14B 149986 NM_144703 /// XM_005260302 /// XM_005260303 /// XM_006723715 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 219654_at NM_014241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014241.1 /DEF=Homo sapiens protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a (PTPLA), mRNA. /FEA=mRNA /GEN=PTPLA /PROD=protein tyrosine phosphatase-like (prolineinstead of catalytic arginine), member a /DB_XREF=gi:7657481 /UG=Hs.114062 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a /FL=gb:AF114494.1 gb:NM_014241.1 NM_014241 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A PTPLA 9200 NM_014241 /// XM_005252641 /// XM_006717536 /// XR_428651 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation 219655_at NM_024728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024728.1 /DEF=Homo sapiens hypothetical protein FLJ11808 (FLJ11808), mRNA. /FEA=mRNA /GEN=FLJ11808 /PROD=hypothetical protein FLJ11808 /DB_XREF=gi:13376041 /UG=Hs.114611 hypothetical protein FLJ11808 /FL=gb:NM_024728.1 NM_024728 succinyl-CoA:glutarate-CoA transferase SUGCT 79783 NM_001193311 /// NM_001193312 /// NM_001193313 /// NM_024728 /// XM_006715775 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047369 // succinate-hydroxymethylglutarate CoA-transferase activity // inferred from direct assay 219656_at NM_016580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016580.1 /DEF=Homo sapiens protocadherin 12 (PCDH12), mRNA. /FEA=mRNA /GEN=PCDH12 /PROD=protocadherin 12 /DB_XREF=gi:7706112 /UG=Hs.115897 protocadherin 12 /FL=gb:AF231025.1 gb:AB026893.1 gb:NM_016580.1 gb:AF240635.1 NM_016580 protocadherin 12 PCDH12 51294 NM_016580 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0008038 // neuron recognition // traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 219657_s_at NM_016531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016531.1 /DEF=Homo sapiens hBKLF for basic kruppel like factor (LOC51274), mRNA. /FEA=mRNA /GEN=LOC51274 /PROD=hBKLF for basic kruppel like factor /DB_XREF=gi:7706076 /UG=Hs.119640 hBKLF for basic kruppel like factor /FL=gb:AF285837.1 gb:AB024523.1 gb:NM_016531.1 NM_016531 Kruppel-like factor 3 (basic) KLF3 51274 NM_016531 /// XM_006714015 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 1901653 // cellular response to peptide // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219658_at NM_024754 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024754.1 /DEF=Homo sapiens hypothetical protein FLJ12598 (FLJ12598), mRNA. /FEA=mRNA /GEN=FLJ12598 /PROD=hypothetical protein FLJ12598 /DB_XREF=gi:13376085 /UG=Hs.126906 hypothetical protein FLJ12598 /FL=gb:NM_024754.1 NM_024754 pentatricopeptide repeat domain 2 PTCD2 79810 NM_001284403 /// NM_001284404 /// NM_001284405 /// NM_024754 /// XM_005248601 /// XM_005248603 /// XR_241790 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 219659_at AU146927 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU146927 /FEA=EST /DB_XREF=gi:11008448 /DB_XREF=est:AU146927 /CLONE=HEMBB1001906 /UG=Hs.130489 ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2 /FL=gb:AF236871.1 gb:NM_016529.1 AU146927 ATPase, aminophospholipid transporter, class I, type 8A, member 2 ATP8A2 51761 NM_016529 /// XM_005266419 /// XM_006719832 /// XM_006719833 /// XM_006719834 /// XM_006719835 /// XM_006719836 /// XR_429216 0003011 // involuntary skeletal muscle contraction // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219660_s_at NM_016529 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016529.1 /DEF=Homo sapiens ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2 (ATP8A2), mRNA. /FEA=mRNA /GEN=ATP8A2 /PROD=ATPase, aminophospholipid transporter-like,Class I, type 8A, member 2 /DB_XREF=gi:7706560 /UG=Hs.130489 ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2 /FL=gb:AF236871.1 gb:NM_016529.1 NM_016529 ATPase, aminophospholipid transporter, class I, type 8A, member 2 ATP8A2 51761 NM_016529 /// XM_005266419 /// XM_006719832 /// XM_006719833 /// XM_006719834 /// XM_006719835 /// XM_006719836 /// XR_429216 0003011 // involuntary skeletal muscle contraction // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219661_at NM_022897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022897.1 /DEF=Homo sapiens RAN binding protein 17 (RANBP17), mRNA. /FEA=mRNA /GEN=RANBP17 /PROD=RAN binding protein 17 /DB_XREF=gi:12597632 /UG=Hs.15032 RAN binding protein 17 /FL=gb:AF222747.1 gb:NM_022897.1 NM_022897 RAN binding protein 17 RANBP17 64901 NM_022897 0006606 // protein import into nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005525 // GTP binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 219662_at NM_024093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024093.1 /DEF=Homo sapiens hypothetical protein MGC5509 (MGC5509), mRNA. /FEA=mRNA /GEN=MGC5509 /PROD=hypothetical protein MGC5509 /DB_XREF=gi:13129093 /UG=Hs.153385 hypothetical protein MGC5509 /FL=gb:BC001310.1 gb:NM_024093.1 NM_024093 chromosome 2 open reading frame 49 C2orf49 79074 NM_001286537 /// NM_024093 /// XM_005264019 /// XM_005264020 0048598 // embryonic morphogenesis // inferred from electronic annotation 0072669 // tRNA-splicing ligase complex // inferred from direct assay 219663_s_at NM_025268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025268.1 /DEF=Homo sapiens hypothetical protein MGC4659 (MGC4659), mRNA. /FEA=mRNA /GEN=MGC4659 /PROD=hypothetical protein MGC4659 /DB_XREF=gi:13376887 /UG=Hs.157527 hypothetical protein MGC4659 /FL=gb:BC004221.1 gb:NM_025268.1 NM_025268 transmembrane protein 121 TMEM121 80757 NM_025268 /// XM_005268101 /// XM_006720261 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219664_s_at NM_020664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020664.1 /DEF=Homo sapiens 2,4-dienoyl CoA reductase 2, peroxisomal (DECR2), mRNA. /FEA=mRNA /GEN=DECR2 /PROD=peroxisomal 2,4-dienoyl-CoA reductase /DB_XREF=gi:10190703 /UG=Hs.15898 2,4-dienoyl CoA reductase 2, peroxisomal /FL=gb:NM_020664.1 NM_020664 2,4-dienoyl CoA reductase 2, peroxisomal DECR2 26063 NM_020664 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0008670 // 2,4-dienoyl-CoA reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019166 // trans-2-enoyl-CoA reductase (NADPH) activity // inferred from direct assay 219665_at NM_024815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024815.1 /DEF=Homo sapiens hypothetical protein FLJ22494 (FLJ22494), mRNA. /FEA=mRNA /GEN=FLJ22494 /PROD=hypothetical protein FLJ22494 /DB_XREF=gi:13376205 /UG=Hs.170132 hypothetical protein FLJ22494 /FL=gb:NM_024815.1 NM_024815 nudix (nucleoside diphosphate linked moiety X)-type motif 18 NUDT18 79873 NM_024815 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0034656 // nucleobase-containing small molecule catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046057 // dADP catabolic process // inferred from direct assay /// 0046067 // dGDP catabolic process // inferred from direct assay /// 0046712 // GDP catabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044715 // 8-oxo-dGDP phosphatase activity // inferred from direct assay /// 0044716 // 8-oxo-GDP phosphatase activity // inferred from direct assay /// 0044717 // 8-hydroxy-dADP phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219666_at NM_022349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022349.1 /DEF=Homo sapiens CD20-like precusor (LOC64166), mRNA. /FEA=mRNA /GEN=LOC64166 /PROD=CD20-like precusor /DB_XREF=gi:11641258 /UG=Hs.17914 membrane-spanning 4-domains, subfamily A, member6 /FL=gb:AF142409.1 gb:NM_022349.1 NM_022349 membrane-spanning 4-domains, subfamily A, member 6A MS4A6A 64231 NM_001247999 /// NM_022349 /// NM_152851 /// NM_152852 /// XM_005274177 /// XM_005274178 /// XM_006718658 /// XM_006718659 /// XM_006718660 /// XM_006718661 /// XM_006718662 /// XM_006718663 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219667_s_at NM_017935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017935.1 /DEF=Homo sapiens hypothetical protein FLJ20706 (FLJ20706), mRNA. /FEA=mRNA /GEN=FLJ20706 /PROD=hypothetical protein FLJ20706 /DB_XREF=gi:8923635 /UG=Hs.193736 hypothetical protein FLJ20706 /FL=gb:NM_017935.1 NM_017935 B-cell scaffold protein with ankyrin repeats 1 BANK1 55024 NM_001083907 /// NM_001127507 /// NM_017935 0042113 // B cell activation // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219668_at NM_024034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024034.1 /DEF=Homo sapiens hypothetical protein MGC3129 similar to ganglioside-induced differentiation-associated protein (MGC3129), mRNA. /FEA=mRNA /GEN=MGC3129 /PROD=hypothetical protein MGC3129 similar toganglioside-induced differentiation-associated protein /DB_XREF=gi:13128983 /UG=Hs.20977 hypothetical protein MGC3129 similar to ganglioside-induced differentiation-associated protein /FL=gb:BC000199.1 gb:NM_024034.1 NM_024034 ganglioside induced differentiation associated protein 1-like 1 GDAP1L1 78997 NM_001256737 /// NM_001256738 /// NM_001256739 /// NM_001256740 /// NM_024034 /// NR_046353 /// XR_244149 /// XR_244150 0005515 // protein binding // inferred from electronic annotation 219669_at NM_020406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020406.1 /DEF=Homo sapiens polycythemia rubra vera 1; cell surface receptor (PRV1), mRNA. /FEA=mRNA /GEN=PRV1 /PROD=polycythemia rubra vera 1; cell surfacereceptor /DB_XREF=gi:9966888 /UG=Hs.232165 polycythemia rubra vera 1; cell surface receptor /FL=gb:AF146747.1 gb:NM_020406.1 NM_020406 CD177 molecule CD177 57126 NM_020406 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 219670_at NM_024603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024603.1 /DEF=Homo sapiens hypothetical protein FLJ11588 (FLJ11588), mRNA. /FEA=mRNA /GEN=FLJ11588 /PROD=hypothetical protein FLJ11588 /DB_XREF=gi:13375806 /UG=Hs.26270 hypothetical protein FLJ11588 /FL=gb:NM_024603.1 NM_024603 BEN domain containing 5 BEND5 79656 NM_024603 /// XM_005271199 /// XM_006710895 /// XM_006710896 /// XM_006710897 0005794 // Golgi apparatus // inferred from electronic annotation 219671_at AL136591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136591.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G122 (from clone DKFZp761G122); complete cds. /FEA=mRNA /GEN=DKFZp761G122 /PROD=hypothetical protein /DB_XREF=gi:13276684 /UG=Hs.272891 hippocalcin-like protein 4 /FL=gb:AL136591.1 gb:AB001105.1 gb:NM_016257.1 AL136591 hippocalcin like 4 HPCAL4 51440 NM_001282396 /// NM_001282397 /// NM_016257 0007417 // central nervous system development // traceable author statement 0005622 // intracellular // inferred from direct assay 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219672_at NM_016633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016633.1 /DEF=Homo sapiens EDRF protein (LOC51327), mRNA. /FEA=mRNA /GEN=LOC51327 /PROD=EDRF protein /DB_XREF=gi:7706179 /UG=Hs.274309 erythroid differentiation-related factor /FL=gb:AF208865.1 gb:NM_016633.1 NM_016633 alpha hemoglobin stabilizing protein AHSP 51327 NM_016633 /// XM_005255351 /// XM_005255352 0006457 // protein folding // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // non-traceable author statement /// 0030097 // hemopoiesis // non-traceable author statement /// 0050821 // protein stabilization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005833 // hemoglobin complex // non-traceable author statement 0030492 // hemoglobin binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 219673_at NM_017696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017696.1 /DEF=Homo sapiens hypothetical protein FLJ20170 (FLJ20170), mRNA. /FEA=mRNA /GEN=FLJ20170 /PROD=hypothetical protein FLJ20170 /DB_XREF=gi:8923164 /UG=Hs.279008 hypothetical protein FLJ20170 /FL=gb:NM_017696.1 NM_017696 minichromosome maintenance complex component 9 MCM9 254394 NM_017696 /// NM_153255 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007276 // gamete generation // inferred from electronic annotation /// 0007292 // female gamete generation // inferred from sequence or structural similarity /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0097362 // MCM8-MCM9 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 219674_s_at NM_018635 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018635.1 /DEF=Homo sapiens hypothetical protein PRO2900 (PRO2900), mRNA. /FEA=mRNA /GEN=PRO2900 /PROD=hypothetical protein PRO2900 /DB_XREF=gi:8924216 /UG=Hs.283473 hypothetical protein PRO2900 /FL=gb:AF116718.1 gb:NM_018635.1 NM_018635 high density lipoprotein binding protein HDLBP 3069 NM_001243900 /// NM_005336 /// NM_203346 /// XM_005247000 /// XM_005247001 /// XM_005247002 /// XM_005247003 /// XM_006712475 /// XM_006712476 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 219675_s_at NM_025076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025076.1 /DEF=Homo sapiens hypothetical protein FLJ23591 (FLJ23591), mRNA. /FEA=mRNA /GEN=FLJ23591 /PROD=hypothetical protein FLJ23591 /DB_XREF=gi:13376625 /UG=Hs.288158 hypothetical protein FLJ23591 /FL=gb:NM_025076.1 NM_025076 UDP-glucuronate decarboxylase 1 UXS1 80146 NM_001253875 /// NM_001253876 /// NM_025076 /// NR_045607 /// XM_006712775 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0033320 // UDP-D-xylose biosynthetic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048040 // UDP-glucuronate decarboxylase activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 219676_at NM_025231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025231.1 /DEF=Homo sapiens hypothetical protein FLJ22191 (FLJ22191), mRNA. /FEA=mRNA /GEN=FLJ22191 /PROD=hypothetical protein FLJ22191 /DB_XREF=gi:13376833 /UG=Hs.288539 hypothetical protein FLJ22191 /FL=gb:BC004255.1 gb:NM_025231.1 NM_025231 zinc finger and SCAN domain containing 16 ZSCAN16 80345 NM_025231 /// XM_005249426 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219677_at NM_025106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025106.1 /DEF=Homo sapiens hypothetical protein FLJ22393 (FLJ22393), mRNA. /FEA=mRNA /GEN=FLJ22393 /PROD=hypothetical protein FLJ22393 /DB_XREF=gi:13376674 /UG=Hs.288641 hypothetical protein FLJ22393 /FL=gb:NM_025106.1 NM_025106 splA/ryanodine receptor domain and SOCS box containing 1 SPSB1 80176 NM_025106 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219678_x_at NM_022487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022487.1 /DEF=Homo sapiens hypothetical protein FLJ11360 (FLJ11360), mRNA. /FEA=mRNA /GEN=FLJ11360 /PROD=hypothetical protein FLJ11360 /DB_XREF=gi:11968040 /UG=Hs.28891 hypothetical protein FLJ11360 /FL=gb:NM_022487.1 NM_022487 DNA cross-link repair 1C DCLRE1C 64421 NM_001033855 /// NM_001033857 /// NM_001033858 /// NM_001289076 /// NM_001289077 /// NM_001289078 /// NM_001289079 /// NM_022487 /// NR_110297 /// XM_005252558 /// XM_006717491 /// XR_242702 0000723 // telomere maintenance // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 219679_s_at NM_018604 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018604.1 /DEF=Homo sapiens hypothetical protein PRO1741 (PRO1741), mRNA. /FEA=mRNA /GEN=PRO1741 /PROD=hypothetical protein PRO1741 /DB_XREF=gi:8924074 /UG=Hs.306067 hypothetical protein PRO1741 /FL=gb:AF116666.1 gb:NM_018604.1 NM_018604 WW domain containing adaptor with coiled-coil WAC 51322 NM_016628 /// NM_100264 /// NM_100486 /// NR_024557 /// XM_005252454 /// XM_005252457 /// XM_005252459 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0010390 // histone monoubiquitination // inferred from mutant phenotype /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0044783 // G1 DNA damage checkpoint // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0071894 // histone H2B conserved C-terminal lysine ubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219680_at NM_024618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024618.1 /DEF=Homo sapiens hypothetical protein FLJ21478 (FLJ21478), mRNA. /FEA=mRNA /GEN=FLJ21478 /PROD=hypothetical protein FLJ21478 /DB_XREF=gi:13375837 /UG=Hs.31097 hypothetical protein FLJ21478 /FL=gb:NM_024618.1 NM_024618 NLR family member X1 NLRX1 79671 NM_001282143 /// NM_001282144 /// NM_001282358 /// NM_024618 /// NM_170722 /// XM_005271669 /// XM_005271670 /// XM_005271671 /// XM_005271672 /// XM_006718904 0002376 // immune system process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032688 // negative regulation of interferon-beta production // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from electronic annotation /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 219681_s_at NM_025151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025151.1 /DEF=Homo sapiens hypothetical protein FLJ22622 (FLJ22622), mRNA. /FEA=mRNA /GEN=FLJ22622 /PROD=hypothetical protein FLJ22622 /DB_XREF=gi:13376744 /UG=Hs.324841 hypothetical protein FLJ22622 /FL=gb:NM_025151.1 NM_025151 RAB11 family interacting protein 1 (class I) RAB11FIP1 80223 NM_001002233 /// NM_001002814 /// NM_025151 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219682_s_at NM_016569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016569.1 /DEF=Homo sapiens TBX3-iso protein (TBX3-iso), mRNA. /FEA=mRNA /GEN=TBX3-iso /PROD=TBX3-iso protein /DB_XREF=gi:7706728 /UG=Hs.332150 TBX3-iso protein /FL=gb:AF216750.1 gb:NM_016569.1 NM_016569 T-box 3 TBX3 6926 NM_005996 /// NM_016569 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003167 // atrioventricular bundle cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007569 // cell aging // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008595 // anterior/posterior axis specification, embryo // inferred from mutant phenotype /// 0009887 // organ morphogenesis // inferred from direct assay /// 0010159 // specification of organ position // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021761 // limbic system development // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from mutant phenotype /// 0030540 // female genitalia development // inferred from mutant phenotype /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from mutant phenotype /// 0032275 // luteinizing hormone secretion // inferred from mutant phenotype /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from mutant phenotype /// 0035136 // forelimb morphogenesis // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046884 // follicle-stimulating hormone secretion // inferred from mutant phenotype /// 0048332 // mesoderm morphogenesis // inferred from mutant phenotype /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0060923 // cardiac muscle cell fate commitment // inferred from electronic annotation /// 0060931 // sinoatrial node cell development // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 2000648 // positive regulation of stem cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 219683_at NM_017412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017412.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 3 (FZD3), mRNA. /FEA=mRNA /GEN=FZD3 /PROD=frizzled (Drosophila) homolog 3 /DB_XREF=gi:8393377 /UG=Hs.40735 frizzled (Drosophila) homolog 3 /FL=gb:AY005130.3 gb:AB039723.1 gb:NM_017412.1 NM_017412 frizzled class receptor 3 FZD3 7976 NM_017412 /// NM_145866 0001736 // establishment of planar polarity // not recorded /// 0001764 // neuron migration // inferred from electronic annotation /// 0001843 // neural tube closure // not recorded /// 0001942 // hair follicle development // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021754 // facial nucleus development // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from electronic annotation /// 0033278 // cell proliferation in midbrain // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0071679 // commissural neuron axon guidance // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0032589 // neuron projection membrane // not recorded /// 0043025 // neuronal cell body // not recorded /// 0045177 // apical part of cell // not recorded /// 0048786 // presynaptic active zone // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0042813 // Wnt-activated receptor activity // inferred by curator 219684_at NM_022147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022147.1 /DEF=Homo sapiens 28kD interferon responsive protein (IFRG28), mRNA. /FEA=mRNA /GEN=IFRG28 /PROD=28kD interferon responsive protein /DB_XREF=gi:11545889 /UG=Hs.43388 28kD interferon responsive protein /FL=gb:NM_022147.1 NM_022147 receptor (chemosensory) transporter protein 4 RTP4 64108 NM_022147 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0006612 // protein targeting to membrane // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219685_at NM_021637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021637.1 /DEF=Homo sapiens hypothetical protein FLJ14084 (FLJ14084), mRNA. /FEA=mRNA /GEN=FLJ14084 /PROD=hypothetical protein FLJ14084 /DB_XREF=gi:11056011 /UG=Hs.45140 hypothetical protein FLJ14084 /FL=gb:NM_021637.1 NM_021637 transmembrane protein 35 TMEM35 59353 NM_021637 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 219686_at NM_018401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018401.1 /DEF=Homo sapiens gene for serinethreonine protein kinase (HSA250839), mRNA. /FEA=mRNA /GEN=HSA250839 /PROD=gene for serinethreonine protein kinase /DB_XREF=gi:8923753 /UG=Hs.58241 gene for serinethreonine protein kinase /FL=gb:NM_018401.1 NM_018401 serine/threonine kinase 32B STK32B 55351 NM_018401 /// XM_005247982 /// XM_005247983 /// XM_006713893 /// XM_006713894 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219687_at NM_018194 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018194.1 /DEF=Homo sapiens hypothetical protein FLJ10724 (FLJ10724), mRNA. /FEA=mRNA /GEN=FLJ10724 /PROD=hypothetical protein FLJ10724 /DB_XREF=gi:8922620 /UG=Hs.58650 melanoma antigen recognized by T cells 2 /FL=gb:NM_018194.1 NM_018194 hedgehog acyltransferase HHAT 55733 NM_001122834 /// NM_001170564 /// NM_001170580 /// NM_001170587 /// NM_001170588 /// NM_018194 /// XM_006711441 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016409 // palmitoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 219688_at NM_018190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018190.1 /DEF=Homo sapiens hypothetical protein FLJ10715 (FLJ10715), mRNA. /FEA=mRNA /GEN=FLJ10715 /PROD=hypothetical protein FLJ10715 /DB_XREF=gi:8922614 /UG=Hs.58974 hypothetical protein FLJ10715 /FL=gb:NM_018190.1 NM_018190 Bardet-Biedl syndrome 7 BBS7 55212 NM_018190 /// NM_176824 /// XM_005263106 0001654 // eye development // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from physical interaction /// 0006810 // transport // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from physical interaction /// 0035058 // nonmotile primary cilium assembly // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0048546 // digestive tract morphogenesis // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051877 // pigment granule aggregation in cell center // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 219689_at NM_020163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020163.1 /DEF=Homo sapiens semaphorin sem2 (LOC56920), mRNA. /FEA=mRNA /GEN=LOC56920 /PROD=semaphorin sem2 /DB_XREF=gi:9910361 /UG=Hs.59729 semaphorin sem2 /FL=gb:AB029496.1 gb:NM_020163.1 NM_020163 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G SEMA3G 56920 NM_020163 /// XM_005265327 0007275 // multicellular organismal development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219690_at NM_024660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024660.1 /DEF=Homo sapiens hypothetical protein FLJ22573 (FLJ22573), mRNA. /FEA=mRNA /GEN=FLJ22573 /PROD=hypothetical protein FLJ22573 /DB_XREF=gi:13375912 /UG=Hs.62406 hypothetical protein FLJ22573 /FL=gb:NM_024660.1 NM_024660 IGF-like family receptor 1 IGFLR1 79713 NM_024660 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219691_at NM_017654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017654.1 /DEF=Homo sapiens hypothetical protein FLJ20073 (FLJ20073), mRNA. /FEA=mRNA /GEN=FLJ20073 /PROD=hypothetical protein FLJ20073 /DB_XREF=gi:8923080 /UG=Hs.65641 hypothetical protein FLJ20073 /FL=gb:NM_017654.1 NM_017654 sterile alpha motif domain containing 9 SAMD9 54809 NM_001193307 /// NM_017654 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219692_at NM_024507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024507.1 /DEF=Homo sapiens hypothetical protein MGC10791 (MGC10791), mRNA. /FEA=mRNA /GEN=MGC10791 /PROD=hypothetical protein MGC10791 /DB_XREF=gi:13375641 /UG=Hs.73452 hypothetical protein MGC10791 /FL=gb:BC003533.1 gb:NM_024507.1 NM_024507 kringle containing transmembrane protein 2 KREMEN2 79412 NM_001253725 /// NM_001253726 /// NM_024507 /// NM_145347 /// NM_145348 /// NM_172229 0016055 // Wnt signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219693_at NM_020133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020133.1 /DEF=Homo sapiens lysophosphatidic acid acyltransferase-delta (LPAAT-delta), mRNA. /FEA=mRNA /GEN=LPAAT-delta /PROD=lysophosphatidic acid acyltransferase-delta /DB_XREF=gi:9910391 /UG=Hs.7869 lysophosphatidic acid acyltransferase-delta /FL=gb:AF156776.1 gb:NM_020133.1 NM_020133 1-acylglycerol-3-phosphate O-acyltransferase 4 AGPAT4 56895 NM_001012733 /// NM_001012734 /// NM_020133 /// XM_005267052 /// XM_005267053 /// XM_005267054 /// XM_005267055 /// XM_006715512 /// XM_006715513 /// XM_006715514 /// XM_006715515 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 219694_at NM_019018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019018.1 /DEF=Homo sapiens hypothetical protein (FLJ11127), mRNA. /FEA=mRNA /GEN=FLJ11127 /PROD=hypothetical protein /DB_XREF=gi:9506640 /UG=Hs.91165 hypothetical protein /FL=gb:NM_019018.1 NM_019018 family with sequence similarity 105, member A FAM105A 54491 NM_019018 219695_at NM_024703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024703.1 /DEF=Homo sapiens hypothetical protein FLJ22593 (FLJ22593), mRNA. /FEA=mRNA /GEN=FLJ22593 /PROD=hypothetical protein FLJ22593 /DB_XREF=gi:13375992 /UG=Hs.101265 hypothetical protein FLJ22593 /FL=gb:NM_024703.1 NM_024703 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) SMPD3 55512 NM_018667 /// XM_005256031 /// XM_005256032 /// XM_006721230 /// XM_006721231 /// XM_006721232 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006684 // sphingomyelin metabolic process // inferred from electronic annotation /// 0006685 // sphingomyelin catabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000137 // Golgi cis cisterna // inferred from electronic annotation /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004767 // sphingomyelin phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219696_at NM_019049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019049.1 /DEF=Homo sapiens hypothetical protein (FLJ20054), mRNA. /FEA=mRNA /GEN=FLJ20054 /PROD=hypothetical protein /DB_XREF=gi:9506654 /UG=Hs.101590 hypothetical protein /FL=gb:NM_019049.1 NM_019049 DENN/MADD domain containing 1B DENND1B 163486 NM_001142795 /// NM_001195215 /// NM_001195216 /// NM_019049 /// NM_144977 /// XM_005244931 /// XM_005244932 /// XM_005244933 /// XM_006711192 /// XM_006711193 /// XM_006711194 /// XR_426763 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 219697_at NM_006043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006043.1 /DEF=Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (HS3ST2), mRNA. /FEA=mRNA /GEN=HS3ST2 /PROD=heparan sulfate D-glucosaminyl3-O-sulfotransferase 2 /DB_XREF=gi:5174462 /UG=Hs.115830 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 /FL=gb:AF105374.1 gb:AF105375.1 gb:NM_006043.1 NM_006043 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 HS3ST2 9956 NM_006043 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0033871 // [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity // inferred from electronic annotation 219698_s_at NM_022840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022840.1 /DEF=Homo sapiens hypothetical protein FLJ23017 (FLJ23017), mRNA. /FEA=mRNA /GEN=FLJ23017 /PROD=hypothetical protein FLJ23017 /DB_XREF=gi:12383089 /UG=Hs.122546 hypothetical protein FLJ23017 /FL=gb:NM_022840.1 NM_022840 methyltransferase like 4 METTL4 64863 NM_022840 /// XM_005258132 /// XM_005258133 /// XM_006722339 /// XR_243813 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 219699_at NM_018176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018176.1 /DEF=Homo sapiens hypothetical protein FLJ10675 (FLJ10675), mRNA. /FEA=mRNA /GEN=FLJ10675 /PROD=hypothetical protein FLJ10675 /DB_XREF=gi:8922586 /UG=Hs.12488 hypothetical protein FLJ10675 /FL=gb:NM_018176.1 NM_018176 leucine-rich repeat LGI family, member 2 LGI2 55203 NM_018176 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219700_at NM_020405 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020405.1 /DEF=Homo sapiens tumor endothelial marker 7 precursor (TEM7), mRNA. /FEA=mRNA /GEN=TEM7 /PROD=tumor endothelial marker 7 precursor /DB_XREF=gi:9966886 /UG=Hs.125036 tumor endothelial marker 7 precursor /FL=gb:AF279144.1 gb:NM_020405.1 NM_020405 plexin domain containing 1 PLXDC1 57125 NM_020405 /// XM_006721981 /// XM_006721982 /// XM_006721983 /// XM_006721984 0001525 // angiogenesis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219701_at NM_014548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014548.1 /DEF=Homo sapiens tropomodulin 2 (neuronal) (TMOD2), mRNA. /FEA=mRNA /GEN=TMOD2 /PROD=tropomodulin 2 (neuronal) /DB_XREF=gi:7657646 /UG=Hs.125864 tropomodulin 2 (neuronal) /FL=gb:AF177169.1 gb:NM_014548.1 NM_014548 tropomodulin 2 (neuronal) TMOD2 29767 NM_001142885 /// NM_014548 0007270 // neuron-neuron synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 219702_at NM_021796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021796.1 /DEF=Homo sapiens placenta-specific 1 (PLAC1), mRNA. /FEA=mRNA /GEN=PLAC1 /PROD=placenta-specific 1 /DB_XREF=gi:11496282 /UG=Hs.13026 placenta-specific 1 /FL=gb:AF234654.1 gb:NM_021796.1 NM_021796 placenta-specific 1 PLAC1 10761 NM_021796 0001890 // placenta development // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0090214 // spongiotrophoblast layer developmental growth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 219703_at NM_018365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018365.1 /DEF=Homo sapiens hypothetical protein FLJ11222 (FLJ11222), mRNA. /FEA=mRNA /GEN=FLJ11222 /PROD=hypothetical protein FLJ11222 /DB_XREF=gi:8922949 /UG=Hs.132851 hypothetical protein FLJ11222 /FL=gb:NM_018365.1 NM_018365 meiosis-specific nuclear structural 1 MNS1 55329 NM_018365 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0044782 // cilium organization // inferred from electronic annotation /// 0070986 // left/right axis specification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005930 // axoneme // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation 0042802 // identical protein binding // inferred from direct assay 219704_at NM_015982 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015982.1 /DEF=Homo sapiens germ cell specific Y-box binding protein (LOC51087), mRNA. /FEA=mRNA /GEN=LOC51087 /PROD=germ cell specific Y-box binding protein /DB_XREF=gi:7705750 /UG=Hs.142989 germ cell specific Y-box binding protein /FL=gb:AF096834.1 gb:NM_015982.1 NM_015982 Y box binding protein 2 YBX2 51087 NM_015982 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0009386 // translational attenuation // traceable author statement /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0051100 // negative regulation of binding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0045182 // translation regulator activity // inferred from electronic annotation 219705_at NM_024774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024774.1 /DEF=Homo sapiens hypothetical protein FLJ21924 (FLJ21924), mRNA. /FEA=mRNA /GEN=FLJ21924 /PROD=hypothetical protein FLJ21924 /DB_XREF=gi:13376124 /UG=Hs.143509 hypothetical protein FLJ21924 /FL=gb:NM_024774.1 NM_024774 glutamine and serine rich 1 QSER1 79832 NM_001076786 /// NM_024774 /// XM_006718323 /// XM_006718324 /// XM_006718325 219706_at NM_018347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018347.1 /DEF=Homo sapiens hypothetical protein FLJ11168 (FLJ11168), mRNA. /FEA=mRNA /GEN=FLJ11168 /PROD=hypothetical protein FLJ11168 /DB_XREF=gi:8922912 /UG=Hs.146023 hypothetical protein FLJ11168 /FL=gb:NM_018347.1 NM_018347 adaptor-related protein complex 5, sigma 1 subunit AP5S1 55317 NM_001204446 /// NM_001204447 /// NM_018347 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219707_at NM_014427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014427.2 /DEF=Homo sapiens copine VII (CPNE7), mRNA. /FEA=mRNA /GEN=CPNE7 /PROD=copine 7 /DB_XREF=gi:12545387 /UG=Hs.146219 copine VII /FL=gb:NM_014427.2 NM_014427 copine VII CPNE7 27132 NM_014427 /// NM_153636 /// XM_006721176 /// XR_243505 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219708_at NM_020201 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020201.1 /DEF=Homo sapiens 5(3)-deoxyribonucleotidase (dNT-2); nuclear gene for mitochondrial product (LOC56953), mRNA. /FEA=mRNA /GEN=LOC56953 /PROD=5(3)-deoxyribonucleotidase (dNT-2); nuclear genefor mitochondrial product /DB_XREF=gi:9910371 /UG=Hs.16614 5(3)-deoxyribonucleotidase (dNT-2); nuclear gene for mitochondrial product /FL=gb:AF210652.1 gb:NM_020201.1 NM_020201 5',3'-nucleotidase, mitochondrial NT5M 56953 NM_020201 /// XM_005256731 /// XM_005256732 /// XM_005256733 /// XM_005256734 /// XM_005256737 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009223 // pyrimidine deoxyribonucleotide catabolic process // traceable author statement /// 0016311 // dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046079 // dUMP catabolic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0008252 // nucleotidase activity // traceable author statement /// 0008253 // 5'-nucleotidase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219709_x_at NM_023933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023933.1 /DEF=Homo sapiens hypothetical protein MGC2494 (MGC2494), mRNA. /FEA=mRNA /GEN=MGC2494 /PROD=hypothetical protein MGC2494 /DB_XREF=gi:13027599 /UG=Hs.166244 hypothetical protein MGC2494 /FL=gb:BC001181.1 gb:BC002624.1 gb:NM_023933.1 NM_023933 family with sequence similarity 173, member A FAM173A 65990 NM_001271285 /// NM_023933 /// XR_243298 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219710_at NM_024577 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024577.1 /DEF=Homo sapiens hypothetical protein FLJ13605 (FLJ13605), mRNA. /FEA=mRNA /GEN=FLJ13605 /PROD=hypothetical protein FLJ13605 /DB_XREF=gi:13375753 /UG=Hs.17244 hypothetical protein FLJ13605 /FL=gb:NM_024577.1 NM_024577 SH3 domain and tetratricopeptide repeats 2 SH3TC2 79628 NM_024577 0008219 // cell death // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0033157 // regulation of intracellular protein transport // inferred from electronic annotation /// 1901184 // regulation of ERBB signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219711_at NM_017652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017652.1 /DEF=Homo sapiens hypothetical protein FLJ20070 (FLJ20070), mRNA. /FEA=mRNA /GEN=FLJ20070 /PROD=hypothetical protein FLJ20070 /DB_XREF=gi:8923076 /UG=Hs.186711 hypothetical protein FLJ20070 /FL=gb:NM_017652.1 NM_017652 zinc finger protein 586 ZNF586 54807 NM_001077426 /// NM_001204814 /// NM_017652 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219712_s_at NM_013276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013276.1 /DEF=Homo sapiens carbohydrate kinase-like (CARKL), mRNA. /FEA=mRNA /GEN=CARKL /PROD=carbohydrate kinase-like /DB_XREF=gi:7019340 /UG=Hs.190207 carbohydrate kinase-like /FL=gb:AF163573.1 gb:NM_013276.1 NM_013276 sedoheptulokinase /// transient receptor potential cation channel, subfamily V, member 1 SHPK /// TRPV1 7442 /// 23729 NM_013276 /// NM_018727 /// NM_080704 /// NM_080705 /// NM_080706 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007635 // chemosensory behavior // traceable author statement /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035963 // cellular response to interleukin-13 // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050955 // thermoception // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071312 // cellular response to alkaloid // inferred from sequence or structural similarity /// 0071318 // cellular response to ATP // inferred from sequence or structural similarity /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005231 // excitatory extracellular ligand-gated ion channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0015278 // calcium-release channel activity // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0050277 // sedoheptulokinase activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 219713_at NM_013276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013276.1 /DEF=Homo sapiens carbohydrate kinase-like (CARKL), mRNA. /FEA=mRNA /GEN=CARKL /PROD=carbohydrate kinase-like /DB_XREF=gi:7019340 /UG=Hs.190207 carbohydrate kinase-like /FL=gb:AF163573.1 gb:NM_013276.1 NM_013276 sedoheptulokinase SHPK 23729 NM_013276 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from direct assay /// 0035963 // cellular response to interleukin-13 // inferred from sequence or structural similarity /// 0043030 // regulation of macrophage activation // inferred from sequence or structural similarity /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071353 // cellular response to interleukin-4 // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0050277 // sedoheptulokinase activity // inferred from direct assay 219714_s_at NM_018398 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018398.1 /DEF=Homo sapiens calcium channel alpha2-delta3 subunit (HSA272268), mRNA. /FEA=mRNA /GEN=HSA272268 /PROD=calcium channel alpha2-delta3 subunit /DB_XREF=gi:8923764 /UG=Hs.22958 calcium channel, voltage-dependent, alpha 2delta 3 subunit /FL=gb:NM_018398.1 NM_018398 calcium channel, voltage-dependent, alpha 2/delta subunit 3 CACNA2D3 55799 NM_018398 /// XM_005265318 /// XM_005265319 /// XR_245150 /// XR_427281 /// XR_427282 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219715_s_at NM_018319 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018319.1 /DEF=Homo sapiens hypothetical protein FLJ11090 (FLJ11090), mRNA. /FEA=mRNA /GEN=FLJ11090 /PROD=hypothetical protein FLJ11090 /DB_XREF=gi:8922860 /UG=Hs.238039 hypothetical protein FLJ11090 /FL=gb:NM_018319.1 NM_018319 tyrosyl-DNA phosphodiesterase 1 TDP1 55775 NM_001008744 /// NM_018319 /// XM_005267847 /// XM_005267848 /// XM_006720197 /// XM_006720198 /// XM_006720199 /// XM_006720200 /// XM_006720201 0000012 // single strand break repair // inferred from direct assay /// 0000012 // single strand break repair // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017005 // 3'-tyrosyl-DNA phosphodiesterase activity // inferred from direct assay 219716_at NM_030641 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030641.1 /DEF=Homo sapiens apolipoprotein L, 6 (APOL6), mRNA. /FEA=mRNA /GEN=APOL6 /PROD=apolipoprotein L, 6 /DB_XREF=gi:13449280 /UG=Hs.257352 apolipoprotein L, 6 /FL=gb:AY014879.1 gb:NM_030641.1 NM_030641 apolipoprotein L, 6 APOL6 80830 NM_030641 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005319 // lipid transporter activity // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 219717_at NM_017741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017741.1 /DEF=Homo sapiens hypothetical protein FLJ20280 (FLJ20280), mRNA. /FEA=mRNA /GEN=FLJ20280 /PROD=hypothetical protein FLJ20280 /DB_XREF=gi:8923256 /UG=Hs.270134 hypothetical protein FLJ20280 /FL=gb:NM_017741.1 NM_017741 DDB1 and CUL4 associated factor 16 DCAF16 54876 NM_017741 /// XM_005248169 /// XM_005248170 /// XM_005248171 /// XM_006713966 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219718_at NM_018291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018291.1 /DEF=Homo sapiens hypothetical protein FLJ10986 (FLJ10986), mRNA. /FEA=mRNA /GEN=FLJ10986 /PROD=hypothetical protein FLJ10986 /DB_XREF=gi:8922805 /UG=Hs.273333 hypothetical protein FLJ10986 /FL=gb:BC000610.1 gb:NM_018291.1 NM_018291 FGGY carbohydrate kinase domain containing FGGY 55277 NM_001113411 /// NM_001244714 /// NM_001278224 /// NM_018291 /// NR_103473 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0070050 // neuron cellular homeostasis // inferred from mutant phenotype 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 219719_at NM_016438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016438.1 /DEF=Homo sapiens CLST 11240 protein (CLST11240), mRNA. /FEA=mRNA /GEN=CLST11240 /PROD=CLST 11240 protein /DB_XREF=gi:7706542 /UG=Hs.274127 CLST 11240 protein /FL=gb:AB038021.1 gb:AB038022.1 gb:NM_016438.1 NM_016438 HIG1 hypoxia inducible domain family, member 1B HIGD1B 51751 NM_001271880 /// NM_016438 /// NR_073504 /// XM_006721946 /// XM_006721947 /// XM_006721948 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219720_s_at NM_017972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017972.1 /DEF=Homo sapiens hypothetical protein FLJ10033 (FLJ10033), mRNA. /FEA=mRNA /GEN=FLJ10033 /PROD=hypothetical protein FLJ10033 /DB_XREF=gi:11034828 /UG=Hs.279844 hypothetical protein FLJ10033 /FL=gb:NM_017972.1 NM_017972 G patch domain containing 2-like GPATCH2L 55668 NM_017926 /// NM_017972 /// NR_110314 /// XM_006720191 /// XM_006720192 /// XM_006720193 0005515 // protein binding // inferred from physical interaction 219721_at NM_018350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018350.1 /DEF=Homo sapiens hypothetical protein FLJ11181 (FLJ11181), mRNA. /FEA=mRNA /GEN=FLJ11181 /PROD=hypothetical protein FLJ11181 /DB_XREF=gi:8922918 /UG=Hs.28472 hypothetical protein FLJ11181 /FL=gb:NM_018350.1 NM_018350 219722_s_at NM_024307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024307.1 /DEF=Homo sapiens hypothetical protein MGC4171 (MGC4171), mRNA. /FEA=mRNA /GEN=MGC4171 /PROD=hypothetical protein MGC4171 /DB_XREF=gi:13236539 /UG=Hs.289015 hypothetical protein MGC4171 /FL=gb:NM_024307.1 NM_024307 glycerophosphodiester phosphodiesterase domain containing 3 GDPD3 79153 NM_024307 /// XR_243306 /// XR_243307 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219723_x_at NM_020132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020132.1 /DEF=Homo sapiens lysophosphatidic acid acyltransferase-gamma1 (LPAAT-gamma1), mRNA. /FEA=mRNA /GEN=LPAAT-gamma1 /PROD=lysophosphatidic acid acyltransferase-gamma1 /DB_XREF=gi:9910393 /UG=Hs.324020 lysophosphatidic acid acyltransferase-gamma1 /FL=gb:AF156774.1 gb:NM_020132.1 NM_020132 1-acylglycerol-3-phosphate O-acyltransferase 3 AGPAT3 56894 NM_001037553 /// NM_020132 /// XM_005261159 /// XM_005261160 /// XM_006724029 /// XM_006724030 /// XM_006724031 /// XM_006724032 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 219724_s_at NM_014796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014796.1 /DEF=Homo sapiens KIAA0748 gene product (KIAA0748), mRNA. /FEA=mRNA /GEN=KIAA0748 /PROD=KIAA0748 gene product /DB_XREF=gi:7662281 /UG=Hs.33187 KIAA0748 gene product /FL=gb:AB018291.1 gb:NM_014796.1 NM_014796 thymocyte expressed, positive selection associated 1 TESPA1 9840 NM_001098815 /// NM_001136030 /// NM_001261844 /// NM_014796 /// XM_005269243 /// XM_005269244 /// XM_005269245 /// XM_005269246 /// XM_005269247 /// XM_006719715 /// XM_006719716 0010387 // COP9 signalosome assembly // inferred from sequence or structural similarity /// 0033089 // positive regulation of T cell differentiation in thymus // inferred from sequence or structural similarity /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation 219725_at NM_018965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018965.1 /DEF=Homo sapiens triggering receptor expressed on myeloid cells 2 (TREM2), mRNA. /FEA=mRNA /GEN=TREM2 /PROD=triggering receptor expressed on myeloid cells2 /DB_XREF=gi:9507202 /UG=Hs.44234 triggering receptor expressed on myeloid cells 2 /FL=gb:AF213457.1 gb:NM_018965.1 NM_018965 triggering receptor expressed on myeloid cells 2 TREM2 54209 NM_001271821 /// NM_018965 /// XM_006715116 0002588 // positive regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from direct assay /// 0006959 // humoral immune response // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050850 // positive regulation of calcium-mediated signaling // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from direct assay /// 1903078 // positive regulation of protein localization to plasma membrane // inferred from direct assay /// 1903082 // positive regulation of C-C chemokine receptor CCR7 signaling pathway // inferred from direct assay /// 2000350 // positive regulation of CD40 signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction 219726_at NM_018977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018977.1 /DEF=Homo sapiens neuroligin 3 (NLGN3), mRNA. /FEA=mRNA /GEN=NLGN3 /PROD=neuroligin 3 /DB_XREF=gi:9506786 /UG=Hs.47320 neuroligin 3 /FL=gb:AF217411.1 gb:NM_018977.1 NM_018977 neuroligin 3 NLGN3 54413 NM_001166660 /// NM_018977 /// NM_181303 /// XM_005262279 /// XM_006724662 /// XM_006724663 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from sequence or structural similarity /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from sequence or structural similarity /// 0007416 // synapse assembly // not recorded /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0048675 // axon extension // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060080 // regulation of inhibitory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from electronic annotation /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 1900271 // regulation of long-term synaptic potentiation // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from electronic annotation /// 2000331 // regulation of terminal button organization // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000969 // positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0045202 // synapse // not recorded /// 0045202 // synapse // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from direct assay 0004872 // receptor activity // not recorded /// 0004872 // receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // not recorded /// 0042043 // neurexin family protein binding // inferred from sequence or structural similarity /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 219727_at NM_014080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014080.1 /DEF=Homo sapiens dual oxidase-like domains 2 (DUOX2), mRNA. /FEA=mRNA /GEN=DUOX2 /PROD=dual oxidase-like domains 2 /DB_XREF=gi:7657434 /UG=Hs.71377 dual oxidase-like domains 2 /FL=gb:AF181972.1 gb:NM_014080.1 gb:AF230496.1 gb:AF267981.1 NM_014080 dual oxidase 2 DUOX2 50506 NM_014080 /// XM_005254421 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042335 // cuticle development // inferred from sequence or structural similarity /// 0042403 // thyroid hormone metabolic process // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0048855 // adenohypophysis morphogenesis // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from direct assay /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0016174 // NAD(P)H oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219728_at NM_006790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006790.1 /DEF=Homo sapiens titin immunoglobulin domain protein (myotilin) (TTID), mRNA. /FEA=mRNA /GEN=TTID /PROD=titin immunoglobulin domain protein /DB_XREF=gi:5803105 /UG=Hs.84665 titin immunoglobulin domain protein (myotilin) /FL=gb:BC005376.1 gb:AF144477.1 gb:NM_006790.1 gb:AF133820.2 NM_006790 myotilin MYOT 9499 NM_001135940 /// NM_006790 /// XM_005272129 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 219729_at NM_016307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016307.2 /DEF=Homo sapiens paired related homeobox protein (PRX2), mRNA. /FEA=mRNA /GEN=PRX2 /PROD=paired related homeobox protein /DB_XREF=gi:12707581 /UG=Hs.86172 paired related homeobox protein /FL=gb:NM_016307.2 gb:AF061970.1 NM_016307 paired related homeobox 2 PRRX2 51450 NM_016307 /// XM_006717142 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 219730_at NM_017638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017638.1 /DEF=Homo sapiens hypothetical protein FLJ20045 (FLJ20045), mRNA. /FEA=mRNA /GEN=FLJ20045 /PROD=hypothetical protein FLJ20045 /DB_XREF=gi:8923052 /UG=Hs.87293 hypothetical protein FLJ20045 /FL=gb:NM_017638.1 NM_017638 mediator of RNA polymerase II transcription subunit 18-like /// mediator complex subunit 18 LOC100996782 /// MED18 54797 /// 100996782 NM_001127350 /// NM_017638 /// XM_003846750 /// XM_005245914 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219731_at NM_024343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024343.1 /DEF=Homo sapiens hypothetical protein MGC10764 (MGC10764), mRNA. /FEA=mRNA /GEN=MGC10764 /PROD=hypothetical protein MGC10764 /DB_XREF=gi:13236594 /UG=Hs.96978 hypothetical protein MGC10764 /FL=gb:BC003519.1 gb:NM_024343.1 NM_024343 ENTPD1 antisense RNA 1 ENTPD1-AS1 728558 NR_038444 219732_at NM_017753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017753.1 /DEF=Homo sapiens hypothetical protein FLJ20300 (FLJ20300), mRNA. /FEA=mRNA /GEN=FLJ20300 /PROD=hypothetical protein FLJ20300 /DB_XREF=gi:8923280 /UG=Hs.106825 hypothetical protein FLJ20300 /FL=gb:NM_017753.1 NM_017753 lipid phosphate phosphatase-related protein type 1 LPPR1 54886 NM_017753 /// NM_207299 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation 219733_s_at NM_012254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012254.1 /DEF=Homo sapiens very long-chain acyl-CoA synthetase homolog 2 (VLCS-H2), mRNA. /FEA=mRNA /GEN=VLCS-H2 /PROD=very long-chain acyl-CoA synthetase homolog 2 /DB_XREF=gi:13325056 /UG=Hs.111401 very long-chain acyl-CoA synthetase homolog 2 /FL=gb:NM_012254.1 gb:AF064255.1 NM_012254 solute carrier family 27 (fatty acid transporter), member 5 SLC27A5 10998 NM_012254 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006642 // triglyceride mobilization // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0015911 // plasma membrane long-chain fatty acid transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015245 // fatty acid transporter activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0047747 // cholate-CoA ligase activity // inferred from electronic annotation 219734_at NM_017699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017699.1 /DEF=Homo sapiens hypothetical protein FLJ20174 (FLJ20174), mRNA. /FEA=mRNA /GEN=FLJ20174 /PROD=hypothetical protein FLJ20174 /DB_XREF=gi:8923170 /UG=Hs.114556 hypothetical protein FLJ20174 /FL=gb:NM_017699.1 NM_017699 SID1 transmembrane family, member 1 SIDT1 54847 NM_017699 /// XM_005247558 /// XM_006713675 /// XM_006713676 /// XM_006713677 /// XM_006713678 /// XM_006713679 /// XM_006713680 /// XR_241500 0016246 // RNA interference // inferred from electronic annotation /// 0033227 // dsRNA transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0051033 // RNA transmembrane transporter activity // inferred from electronic annotation 219735_s_at NM_014553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014553.1 /DEF=Homo sapiens LBP protein (LBP-9), mRNA. /FEA=mRNA /GEN=LBP-9 /PROD=LBP protein /DB_XREF=gi:7657298 /UG=Hs.114747 LBP protein; likely ortholog of mouse CRTR-1 /FL=gb:AF198488.1 gb:NM_014553.1 NM_014553 transcription factor CP2-like 1 TFCP2L1 29842 NM_014553 /// XM_005263651 /// XM_005263652 /// XM_006712459 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007431 // salivary gland development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0045927 // positive regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 219736_at NM_018700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018700.1 /DEF=Homo sapiens zinc-binding protein Rbcc728 (Rbcc728), mRNA. /FEA=mRNA /GEN=Rbcc728 /PROD=zinc-binding protein Rbcc728 /DB_XREF=gi:8924237 /UG=Hs.121429 zinc-binding protein Rbcc728 /FL=gb:NM_018700.1 NM_018700 tripartite motif containing 36 TRIM36 55521 NM_001017397 /// NM_001017398 /// NM_018700 /// XM_005272031 /// XM_005272034 0007340 // acrosome reaction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219737_s_at AI524125 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI524125 /FEA=EST /DB_XREF=gi:4438260 /DB_XREF=est:th09d11.x1 /CLONE=IMAGE:2117781 /UG=Hs.12450 protocadherin 9 /FL=gb:AF169692.2 gb:NM_020403.1 AI524125 protocadherin 9 PCDH9 5101 NM_020403 /// NM_203487 /// XM_005266406 /// XM_005266407 /// XM_005266408 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219738_s_at NM_020403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020403.1 /DEF=Homo sapiens protocadherin 9 (PCDH9), mRNA. /FEA=mRNA /GEN=PCDH9 /PROD=cadherin superfamily protein VR4-11 /DB_XREF=gi:9966882 /UG=Hs.12450 protocadherin 9 /FL=gb:AF169692.2 gb:NM_020403.1 NM_020403 protocadherin 9 PCDH9 5101 NM_020403 /// NM_203487 /// XM_005266406 /// XM_005266407 /// XM_005266408 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219739_at NM_019062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019062.1 /DEF=Homo sapiens hypothetical protein (FLJ20225), mRNA. /FEA=mRNA /GEN=FLJ20225 /PROD=hypothetical protein /DB_XREF=gi:9506662 /UG=Hs.124835 hypothetical protein /FL=gb:NM_019062.1 NM_019062 ring finger protein 186 RNF186 54546 NM_019062 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219740_at NM_024749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024749.1 /DEF=Homo sapiens hypothetical protein FLJ12505 (FLJ12505), mRNA. /FEA=mRNA /GEN=FLJ12505 /PROD=hypothetical protein FLJ12505 /DB_XREF=gi:13376077 /UG=Hs.125741 hypothetical protein FLJ12505 /FL=gb:NM_024749.1 NM_024749 vasohibin 2 VASH2 79805 NM_001136474 /// NM_001136475 /// NM_024749 /// XM_006711541 /// XR_247041 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 219741_x_at NM_024762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024762.1 /DEF=Homo sapiens hypothetical protein FLJ21603 (FLJ21603), mRNA. /FEA=mRNA /GEN=FLJ21603 /PROD=hypothetical protein FLJ21603 /DB_XREF=gi:13443019 /UG=Hs.129691 hypothetical protein FLJ21603 /FL=gb:NM_024762.1 NM_024762 zinc finger protein 552 ZNF552 79818 NM_024762 /// XM_005259267 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219742_at NM_030567 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030567.1 /DEF=Homo sapiens hypothetical protein MGC10772 (MGC10772), mRNA. /FEA=mRNA /GEN=MGC10772 /PROD=hypothetical protein MGC10772 /DB_XREF=gi:13386473 /UG=Hs.130316 hypothetical protein MGC10772 /FL=gb:BC004261.1 gb:NM_030567.1 NM_030567 proline rich 7 (synaptic) PRR7 80758 NM_001174101 /// NM_001174102 /// NM_030567 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 219743_at NM_012259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012259.1 /DEF=Homo sapiens hairyenhancer-of-split related with YRPW motif 2 (HEY2), mRNA. /FEA=mRNA /GEN=HEY2 /PROD=hairyenhancer-of-split related with YRPW motif2 /DB_XREF=gi:6912413 /UG=Hs.144287 hairyenhancer-of-split related with YRPW motif 2 /FL=gb:AF311884.1 gb:AF173901.1 gb:NM_012259.1 gb:AF232238.1 gb:AF237949.1 gb:AB044755.1 NM_012259 hes-related family bHLH transcription factor with YRPW motif 2 HEY2 23493 NM_012259 /// XM_005266878 /// XM_006715428 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0003150 // muscular septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003171 // atrioventricular valve development // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003186 // tricuspid valve morphogenesis // inferred from sequence or structural similarity /// 0003195 // tricuspid valve formation // inferred from electronic annotation /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003300 // cardiac muscle hypertrophy // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010621 // negative regulation of transcription by transcription factor localization // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036304 // umbilical cord morphogenesis // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045607 // regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // non-traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060413 // atrial septum morphogenesis // inferred from sequence or structural similarity /// 0060633 // negative regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0060948 // cardiac vascular smooth muscle cell development // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0061156 // pulmonary artery morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from expression pattern /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000723 // negative regulation of cardiac vascular smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000820 // negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2001212 // regulation of vasculogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation 219744_at NM_022158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022158.1 /DEF=Homo sapiens fructosamine-3-kinase (FN3K), mRNA. /FEA=mRNA /GEN=FN3K /PROD=fructosamine-3-kinase /DB_XREF=gi:11545905 /UG=Hs.151135 fructosamine-3-kinase /FL=gb:NM_022158.1 NM_022158 fructosamine 3 kinase FN3K 64122 NM_022158 0016310 // phosphorylation // inferred from electronic annotation /// 0030389 // fructosamine metabolic process // inferred from electronic annotation /// 0030393 // fructoselysine metabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030387 // fructosamine-3-kinase activity // non-traceable author statement 219745_at NM_024789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024789.1 /DEF=Homo sapiens hypothetical protein FLJ22529 (FLJ22529), mRNA. /FEA=mRNA /GEN=FLJ22529 /PROD=hypothetical protein FLJ22529 /DB_XREF=gi:13376155 /UG=Hs.153503 hypothetical protein FLJ22529 /FL=gb:NM_024789.1 NM_024789 transmembrane protein 180 TMEM180 79847 NM_024789 /// XM_006717971 /// XM_006717972 /// XM_006717973 /// XM_006717974 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219746_at NM_012074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012074.1 /DEF=Homo sapiens cer-d4 (mouse) homolog (CERD4), mRNA. /FEA=mRNA /GEN=CERD4 /PROD=cer-d4 (mouse) homolog /DB_XREF=gi:13442997 /UG=Hs.157492 cer-d4 (mouse) homolog /FL=gb:NM_012074.1 NM_012074 D4, zinc and double PHD fingers, family 3 DPF3 8110 NM_001280542 /// NM_001280543 /// NM_001280544 /// NM_012074 /// XM_005268109 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219747_at NM_024574 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024574.1 /DEF=Homo sapiens hypothetical protein FLJ23191 (FLJ23191), mRNA. /FEA=mRNA /GEN=FLJ23191 /PROD=hypothetical protein FLJ23191 /DB_XREF=gi:13375747 /UG=Hs.16026 hypothetical protein FLJ23191 /FL=gb:NM_024574.1 NM_024574 neuron-derived neurotrophic factor NDNF 79625 NM_024574 0001764 // neuron migration // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016049 // cell growth // inferred from direct assay /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity 219748_at NM_024807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024807.1 /DEF=Homo sapiens hypothetical protein FLJ13693 (FLJ13693), mRNA. /FEA=mRNA /GEN=FLJ13693 /PROD=hypothetical protein FLJ13693 /DB_XREF=gi:13376188 /UG=Hs.164797 hypothetical protein FLJ13693 /FL=gb:NM_024807.1 NM_024807 triggering receptor expressed on myeloid cells-like 2 TREML2 79865 NM_024807 0042110 // T cell activation // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 219749_at NM_022071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022071.1 /DEF=Homo sapiens hypothetical protein FLJ20967 (FLJ20967), mRNA. /FEA=mRNA /GEN=FLJ20967 /PROD=hypothetical protein FLJ20967 /DB_XREF=gi:11545782 /UG=Hs.17433 hypothetical protein FLJ20967 /FL=gb:NM_022071.1 NM_022071 SH2 domain containing 4A SH2D4A 63898 NM_001174159 /// NM_001174160 /// NM_022071 /// XM_006716378 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 219750_at NM_018342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018342.1 /DEF=Homo sapiens hypothetical protein FLJ11155 (FLJ11155), mRNA. /FEA=mRNA /GEN=FLJ11155 /PROD=hypothetical protein FLJ11155 /DB_XREF=gi:8922902 /UG=Hs.176227 hypothetical protein FLJ11155 /FL=gb:NM_018342.1 NM_018342 transmembrane protein 144 TMEM144 55314 NM_018342 /// XM_005263110 /// XM_005263112 /// XM_006714254 /// XM_006714255 0034219 // carbohydrate transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015144 // carbohydrate transmembrane transporter activity // inferred from electronic annotation 219751_at NM_024860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024860.1 /DEF=Homo sapiens hypothetical protein FLJ21148 (FLJ21148), mRNA. /FEA=mRNA /GEN=FLJ21148 /PROD=hypothetical protein FLJ21148 /DB_XREF=gi:13376287 /UG=Hs.193300 hypothetical protein FLJ21148 /FL=gb:NM_024860.1 NM_024860 SET domain containing 6 SETD6 79918 NM_001160305 /// NM_024860 /// XM_006721271 /// XM_006721272 /// XR_243428 /// XR_243429 /// XR_429729 /// XR_429730 0018026 // peptidyl-lysine monomethylation // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction 219752_at NM_004658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004658.1 /DEF=Homo sapiens RAS protein activator like 1 (GAP1 like) (RASAL1), mRNA. /FEA=mRNA /GEN=RASAL1 /PROD=RAS protein activator like 1 /DB_XREF=gi:4759025 /UG=Hs.198312 RAS protein activator like 1 (GAP1 like) /FL=gb:AF086713.1 gb:NM_004658.1 NM_004658 RAS protein activator like 1 (GAP1 like) RASAL1 8437 NM_001193520 /// NM_001193521 /// NM_004658 /// XM_005253950 /// XM_005253951 /// XM_006719641 /// XM_006719642 0007165 // signal transduction // traceable author statement /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219753_at NM_012447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012447.1 /DEF=Homo sapiens stromal antigen 3 (STAG3), mRNA. /FEA=mRNA /GEN=STAG3 /PROD=stromal antigen 3 /DB_XREF=gi:6912685 /UG=Hs.20132 stromal antigen 3 /FL=gb:NM_012447.1 NM_012447 stromal antigen 3 STAG3 10734 NM_001282716 /// NM_001282717 /// NM_001282718 /// NM_012447 /// XM_005250116 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000795 // synaptonemal complex // traceable author statement /// 0000800 // lateral element // inferred from electronic annotation /// 0000802 // transverse filament // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030893 // meiotic cohesin complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation 219754_at NM_018301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018301.1 /DEF=Homo sapiens hypothetical protein FLJ11016 (FLJ11016), mRNA. /FEA=mRNA /GEN=FLJ11016 /PROD=hypothetical protein FLJ11016 /DB_XREF=gi:8922825 /UG=Hs.210859 hypothetical protein FLJ11016 /FL=gb:NM_018301.1 NM_018301 RNA binding motif protein 41 RBM41 55285 NM_001171080 /// NM_018301 /// XM_005262159 /// XM_005262160 /// XM_005262161 /// XM_005262162 /// XM_006724671 /// XR_244476 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 219755_at NM_020649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020649.1 /DEF=Homo sapiens chromobox homolog 8 (Drosophila Pc class) (CBX8), mRNA. /FEA=mRNA /GEN=CBX8 /PROD=chromobox homolog 8 (Drosophila Pc class) /DB_XREF=gi:10190681 /UG=Hs.250005 chromobox homolog 8 (Drosophila Pc class) /FL=gb:NM_020649.1 gb:AF266479.1 gb:AF174482.1 NM_020649 chromobox homolog 8 CBX8 57332 NM_020649 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 219756_s_at NM_024921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024921.1 /DEF=Homo sapiens hypothetical protein FLJ22792 (FLJ22792), mRNA. /FEA=mRNA /GEN=FLJ22792 /PROD=hypothetical protein FLJ22792 /DB_XREF=gi:13376393 /UG=Hs.267038 hypothetical protein FLJ22792 /FL=gb:NM_024921.1 NM_024921 premature ovarian failure, 1B POF1B 79983 NM_024921 /// XM_005262202 /// XM_005262203 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 219757_s_at NM_017799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017799.1 /DEF=Homo sapiens hypothetical protein FLJ20392 (FLJ20392), mRNA. /FEA=mRNA /GEN=FLJ20392 /PROD=hypothetical protein FLJ20392 /DB_XREF=gi:8923365 /UG=Hs.27047 hypothetical protein FLJ20392 /FL=gb:NM_017799.1 NM_017799 transmembrane protein 260 TMEM260 54916 NM_017799 /// XM_005267771 /// XM_006720175 /// XM_006720176 /// XM_006720177 /// XM_006720178 /// XR_245695 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219758_at NM_024926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024926.1 /DEF=Homo sapiens hypothetical protein FLJ12571 (FLJ12571), mRNA. /FEA=mRNA /GEN=FLJ12571 /PROD=hypothetical protein FLJ12571 /DB_XREF=gi:13376399 /UG=Hs.272321 hypothetical protein FLJ12571 /FL=gb:NM_024926.1 NM_024926 tetratricopeptide repeat domain 26 TTC26 79989 NM_001144920 /// NM_001144923 /// NM_001287512 /// NM_001287513 /// NM_024926 /// XM_005250608 /// XM_006716135 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005929 // cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 219759_at NM_022350 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022350.1 /DEF=Homo sapiens aminopeptidase (LOC64167), mRNA. /FEA=mRNA /GEN=LOC64167 /PROD=aminopeptidase /DB_XREF=gi:11641260 /UG=Hs.280380 aminopeptidase /FL=gb:AF191545.1 gb:NM_022350.1 NM_022350 endoplasmic reticulum aminopeptidase 2 ERAP2 64167 NM_001130140 /// NM_022350 /// XR_246538 /// XR_246539 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004177 // aminopeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219760_at NM_022165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022165.1 /DEF=Homo sapiens Lin-7b protein (LIN-7B), mRNA. /FEA=mRNA /GEN=LIN-7B /PROD=Lin-7b protein /DB_XREF=gi:11545919 /UG=Hs.293686 Lin-7b protein; likely ortholog of mouse LIN-7B; mammalian LIN-7 protein 2 /FL=gb:AF311862.1 gb:NM_022165.1 NM_022165 lin-7 homolog B (C. elegans) LIN7B 64130 NM_022165 /// XM_005259149 /// XM_006723323 /// XR_243950 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 219761_at NM_016511 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016511.1 /DEF=Homo sapiens C-type lectin-like receptor-1 (LOC51267), mRNA. /FEA=mRNA /GEN=LOC51267 /PROD=C-type lectin-like receptor-1 /DB_XREF=gi:7706062 /UG=Hs.29549 C-type lectin-like receptor-1 /FL=gb:AF200949.1 gb:NM_016511.1 NM_016511 C-type lectin domain family 1, member A CLEC1A 51267 NM_016511 /// XM_005253383 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement 0005622 // intracellular // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 219762_s_at NM_015414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015414.1 /DEF=Homo sapiens ribosomal protein L36 (RPL36), mRNA. /FEA=mRNA /GEN=RPL36 /PROD=ribosomal protein L36 /DB_XREF=gi:7661637 /UG=Hs.300759 ribosomal protein L36 /FL=gb:AF077043.1 gb:NM_015414.1 NM_015414 ribosomal protein L36 RPL36 25873 NM_015414 /// NM_033643 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 219763_at NM_024820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024820.1 /DEF=Homo sapiens KIAA1608 protein (KIAA1608), mRNA. /FEA=mRNA /GEN=KIAA1608 /PROD=hypothetical protein FLJ21129 /DB_XREF=gi:13449264 /UG=Hs.300842 KIAA1608 protein /FL=gb:NM_024820.1 NM_024820 DENN/MADD domain containing 1A DENND1A 57706 NM_020946 /// NM_024820 /// XM_005252109 /// XM_005252111 /// XM_005252113 /// XM_006717195 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032483 // regulation of Rab protein signal transduction // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation 219764_at NM_007197 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007197.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 10 (FZD10), mRNA. /FEA=mRNA /GEN=FZD10 /PROD=frizzled (Drosophila) homolog 10 /DB_XREF=gi:6005761 /UG=Hs.31664 frizzled (Drosophila) homolog 10 /FL=gb:AB027464.1 gb:NM_007197.1 NM_007197 frizzled class receptor 10 FZD10 11211 NM_007197 0001944 // vasculature development // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0034259 // negative regulation of Rho GTPase activity // inferred from mutant phenotype /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // not recorded /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 219765_at NM_024620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024620.1 /DEF=Homo sapiens hypothetical protein FLJ12586 (FLJ12586), mRNA. /FEA=mRNA /GEN=FLJ12586 /PROD=hypothetical protein FLJ12586 /DB_XREF=gi:13375841 /UG=Hs.31844 hypothetical protein FLJ12586 /FL=gb:NM_024620.1 NM_024620 zinc finger protein 329 ZNF329 79673 NM_024620 /// XM_006723381 /// XM_006723382 /// XM_006723383 /// XM_006723384 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219766_at NM_030578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030578.1 /DEF=Homo sapiens hypothetical protein MGC4093 (MGC4093), mRNA. /FEA=mRNA /GEN=MGC4093 /PROD=hypothetical protein MGC4093 /DB_XREF=gi:13385567 /UG=Hs.31895 hypothetical protein MGC4093 /FL=gb:BC004157.1 gb:BC004444.1 gb:NM_030578.1 NM_030578 B9 protein domain 2 B9D2 80776 NM_030578 /// XM_006723405 0000278 // mitotic cell cycle // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from sequence or structural similarity 219767_s_at NM_005111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005111.1 /DEF=Homo sapiens crystallin, zeta (quinone reductase)-like 1 (CRYZL1), mRNA. /FEA=mRNA /GEN=CRYZL1 /PROD=crystallin, zeta (quinone reductase)-like 1 /DB_XREF=gi:4826679 /UG=Hs.330208 crystallin, zeta (quinone reductase)-like 1 /FL=gb:AF029689.1 gb:NM_005111.1 NM_005111 crystallin, zeta (quinone reductase)-like 1 CRYZL1 9946 NM_145311 /// NM_145858 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901661 // quinone metabolic process // non-traceable author statement 0005829 // cytosol // inferred from direct assay 0003960 // NADPH:quinone reductase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0050661 // NADP binding // non-traceable author statement 219768_at NM_024626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024626.1 /DEF=Homo sapiens hypothetical protein FLJ22418 (FLJ22418), mRNA. /FEA=mRNA /GEN=FLJ22418 /PROD=hypothetical protein FLJ22418 /DB_XREF=gi:13375849 /UG=Hs.36563 hypothetical protein FLJ22418 /FL=gb:NM_024626.1 NM_024626 V-set domain containing T cell activation inhibitor 1 VTCN1 79679 NM_001253849 /// NM_001253850 /// NM_024626 /// NR_045603 /// NR_045604 0001562 // response to protozoan // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0072602 // interleukin-4 secretion // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219769_at NM_020238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020238.1 /DEF=Homo sapiens inner centromere protein antigens (135kD, 155kD) (INCENP), mRNA. /FEA=mRNA /GEN=INCENP /PROD=inner centromere protein antigens (135kD,155kD) /DB_XREF=gi:9910375 /UG=Hs.44836 inner centromere protein antigens (135kD, 155kD) /FL=gb:AF282265.1 gb:NM_020238.1 NM_020238 inner centromere protein antigens 135/155kDa INCENP 3619 NM_001040694 /// NM_020238 /// XM_006718533 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0000801 // central element // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0010369 // chromocenter // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219770_at NM_024659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024659.1 /DEF=Homo sapiens hypothetical protein FLJ11753 (FLJ11753), mRNA. /FEA=mRNA /GEN=FLJ11753 /PROD=hypothetical protein FLJ11753 /DB_XREF=gi:13375910 /UG=Hs.62348 hypothetical protein FLJ11753 /FL=gb:NM_024659.1 NM_024659 glycosyltransferase-like domain containing 1 GTDC1 79712 NM_001006636 /// NM_001164629 /// NM_001284233 /// NM_001284234 /// NM_001284235 /// NM_001284238 /// NM_024659 /// XM_005263771 /// XM_005263774 /// XM_005263775 /// XM_005263777 /// XM_005263782 /// XM_005263784 /// XM_005263786 /// XM_006712752 /// XM_006712753 /// XM_006712754 /// XM_006712755 /// XM_006712756 0009058 // biosynthetic process // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 219771_at NM_017752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017752.1 /DEF=Homo sapiens hypothetical protein FLJ20298 (FLJ20298), mRNA. /FEA=mRNA /GEN=FLJ20298 /PROD=hypothetical protein FLJ20298 /DB_XREF=gi:8923278 /UG=Hs.67055 hypothetical protein FLJ20298 /FL=gb:NM_017752.1 NM_017752 TBC1 domain family, member 8B (with GRAM domain) TBC1D8B 54885 NM_017752 /// NM_198881 /// XM_006724669 /// XM_006724670 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 219772_s_at NM_014332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014332.1 /DEF=Homo sapiens small muscle protein, X-linked (SMPX), mRNA. /FEA=mRNA /GEN=SMPX /PROD=small muscle protein, X-linked /DB_XREF=gi:10047089 /UG=Hs.86492 small muscle protein, X-linked /FL=gb:NM_014332.1 gb:AF129505.1 NM_014332 small muscle protein, X-linked SMPX 23676 NM_014332 /// NR_045617 0006941 // striated muscle contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation 219773_at NM_016931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016931.1 /DEF=Homo sapiens NADPH oxidase 4 (NOX4), mRNA. /FEA=mRNA /GEN=NOX4 /PROD=NADPH oxidase 4 /DB_XREF=gi:8393842 /UG=Hs.93847 NADPH oxidase 4 /FL=gb:AF254621.1 gb:AB041035.1 gb:NM_016931.1 gb:AF261943.1 NM_016931 NADPH oxidase 4 NOX4 50507 NM_001143836 /// NM_001143837 /// NM_001291926 /// NM_001291927 /// NM_001291929 /// NM_016931 /// NR_026571 /// NR_120406 /// XM_006718847 /// XM_006718848 /// XM_006718849 /// XM_006718850 /// XM_006718851 /// XM_006718852 /// XM_006718853 /// XR_428978 /// XR_428979 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016174 // NAD(P)H oxidase activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019826 // oxygen sensor activity // traceable author statement /// 0020037 // heme binding // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050664 // oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 219774_at NM_019044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019044.1 /DEF=Homo sapiens hypothetical protein (FLJ10996), mRNA. /FEA=mRNA /GEN=FLJ10996 /PROD=hypothetical protein /DB_XREF=gi:9506632 /UG=Hs.98324 hypothetical protein /FL=gb:NM_019044.1 NM_019044 coiled-coil domain containing 93 CCDC93 54520 NM_019044 /// XM_006712597 /// XM_006712598 /// XM_006712599 /// XM_006712600 219775_s_at NM_024695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024695.1 /DEF=Homo sapiens hypothetical protein FLJ13993 (FLJ13993), mRNA. /FEA=mRNA /GEN=FLJ13993 /PROD=hypothetical protein FLJ13993 /DB_XREF=gi:13375976 /UG=Hs.98927 hypothetical protein FLJ13993 /FL=gb:NM_024695.1 NM_024695 complexin 3 CPLX3 594855 NM_001030005 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005326 // neurotransmitter transporter activity // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 219776_s_at NM_018331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018331.1 /DEF=Homo sapiens hypothetical protein FLJ11125 (FLJ11125), mRNA. /FEA=mRNA /GEN=FLJ11125 /PROD=hypothetical protein FLJ11125 /DB_XREF=gi:8922883 /UG=Hs.105216 hypothetical protein FLJ11125 /FL=gb:NM_018331.1 NM_018331 219777_at NM_024711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024711.1 /DEF=Homo sapiens hypothetical protein FLJ22690 (FLJ22690), mRNA. /FEA=mRNA /GEN=FLJ22690 /PROD=hypothetical protein FLJ22690 /DB_XREF=gi:13376008 /UG=Hs.105468 hypothetical protein FLJ22690 /FL=gb:NM_024711.1 NM_024711 GTPase, IMAP family member 6 GIMAP6 474344 NM_001007224 /// NM_001244071 /// NM_001244072 /// NM_024711 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219778_at NM_012082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012082.2 /DEF=Homo sapiens Friend of GATA2 (FOG2), mRNA. /FEA=mRNA /GEN=FOG2 /PROD=Friend of GATA2 /DB_XREF=gi:10862688 /UG=Hs.106309 Friend of GATA2 /FL=gb:NM_012082.2 gb:AF119334.1 NM_012082 zinc finger protein, FOG family member 2 ZFPM2 23414 NM_012082 /// XM_005250850 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from mutant phenotype /// 0003221 // right ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from electronic annotation /// 2000195 // negative regulation of female gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0001071 // nucleic acid binding transcription factor activity // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219779_at NM_024721 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024721.1 /DEF=Homo sapiens hypothetical protein FLJ20980 (FLJ20980), mRNA. /FEA=mRNA /GEN=FLJ20980 /PROD=hypothetical protein FLJ20980 /DB_XREF=gi:13376026 /UG=Hs.109314 hypothetical protein FLJ20980 /FL=gb:NM_024721.1 NM_024721 zinc finger homeobox 4 ZFHX4 79776 NM_024721 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219780_at AF242768 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF242768.1 /DEF=Homo sapiens mesenchymal stem cell protein DSC43 mRNA, complete cds. /FEA=mRNA /PROD=mesenchymal stem cell protein DSC43 /DB_XREF=gi:7638236 /UG=Hs.116056 mesenchymal stem cell protein DSC43 /FL=gb:AF242768.1 gb:NM_016643.1 AF242768 zinc finger protein 771 ZNF771 51333 NM_001142305 /// NM_016643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219781_s_at AI992095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI992095 /FEA=EST /DB_XREF=gi:5839000 /DB_XREF=est:ws21g05.x1 /CLONE=IMAGE:2497880 /UG=Hs.116056 mesenchymal stem cell protein DSC43 /FL=gb:AF242768.1 gb:NM_016643.1 AI992095 zinc finger protein 771 ZNF771 51333 NM_001142305 /// NM_016643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219782_s_at NM_016643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016643.1 /DEF=Homo sapiens mesenchymal stem cell protein DSC43 (LOC51333), mRNA. /FEA=mRNA /GEN=LOC51333 /PROD=mesenchymal stem cell protein DSC43 /DB_XREF=gi:7706191 /UG=Hs.116056 mesenchymal stem cell protein DSC43 /FL=gb:AF242768.1 gb:NM_016643.1 NM_016643 zinc finger protein 771 ZNF771 51333 NM_001142305 /// NM_016643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219783_at NM_017877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017877.1 /DEF=Homo sapiens hypothetical protein FLJ20555 (FLJ20555), mRNA. /FEA=mRNA /GEN=FLJ20555 /PROD=hypothetical protein FLJ20555 /DB_XREF=gi:8923523 /UG=Hs.11759 hypothetical protein FLJ20555 /FL=gb:NM_017877.1 NM_017877 solute carrier family 35, member F6 SLC35F6 54978 NM_017877 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219784_at NM_024735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024735.1 /DEF=Homo sapiens hypothetical protein FLJ22477 (FLJ22477), mRNA. /FEA=mRNA /GEN=FLJ22477 /PROD=hypothetical protein FLJ22477 /DB_XREF=gi:13376055 /UG=Hs.118944 hypothetical protein FLJ22477 /FL=gb:NM_024735.1 NM_024735 chromosome 16 open reading frame 95 C16orf95 100506581 NM_001195124 /// NM_001195125 /// NM_001256917 219785_s_at NM_024735 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024735.1 /DEF=Homo sapiens hypothetical protein FLJ22477 (FLJ22477), mRNA. /FEA=mRNA /GEN=FLJ22477 /PROD=hypothetical protein FLJ22477 /DB_XREF=gi:13376055 /UG=Hs.118944 hypothetical protein FLJ22477 /FL=gb:NM_024735.1 NM_024735 chromosome 16 open reading frame 95 C16orf95 100506581 NM_001195124 /// NM_001195125 /// NM_001256917 219786_at NM_004923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004923.1 /DEF=Homo sapiens metallothionein-like 5, testis-specific (tesmin) (MTL5), mRNA. /FEA=mRNA /GEN=MTL5 /PROD=metallothionein-like 5, testis-specific(tesmin) /DB_XREF=gi:4758741 /UG=Hs.121378 metallothionein-like 5, testis-specific (tesmin) /FL=gb:U86074.1 gb:NM_004923.1 NM_004923 metallothionein-like 5, testis-specific (tesmin) MTL5 9633 NM_001039656 /// NM_004923 /// XM_006718751 /// XR_428932 /// XR_428933 /// XR_428934 0006875 // cellular metal ion homeostasis // non-traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0010038 // response to metal ion // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0046872 // metal ion binding // non-traceable author statement 219787_s_at NM_018098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018098.1 /DEF=Homo sapiens hypothetical protein FLJ10461 (FLJ10461), mRNA. /FEA=mRNA /GEN=FLJ10461 /PROD=hypothetical protein FLJ10461 /DB_XREF=gi:8922431 /UG=Hs.122579 hypothetical protein FLJ10461 /FL=gb:NM_018098.1 NM_018098 epithelial cell transforming 2 ECT2 1894 NM_001258315 /// NM_001258316 /// NM_018098 /// XM_005247176 /// XM_005247180 /// XM_006713523 /// XM_006713524 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070830 // tight junction assembly // inferred from mutant phenotype /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay /// 0097149 // centralspindlin complex // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 219788_at NM_013439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013439.1 /DEF=Homo sapiens paired immunoglobulin-like receptor alpha (PILR(ALPHA)), mRNA. /FEA=mRNA /GEN=PILR(ALPHA) /PROD=paired immunoglobulin-like receptor alpha /DB_XREF=gi:7305384 /UG=Hs.122591 paired immunoglobulin-like receptor alpha /FL=gb:AF161080.1 gb:NM_013439.1 NM_013439 paired immunoglobin-like type 2 receptor alpha PILRA 29992 NM_013439 /// NM_178272 /// NM_178273 /// XM_006715954 /// XM_006715955 0007165 // signal transduction // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219789_at AI628360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI628360 /FEA=EST /DB_XREF=gi:4665160 /DB_XREF=est:ty75e10.x1 /CLONE=IMAGE:2284938 /UG=Hs.123655 natriuretic peptide receptor Cguanylate cyclase C (atrionatriuretic peptide receptor C) /FL=gb:M59305.1 gb:AF025998.1 gb:NM_000908.1 AI628360 natriuretic peptide receptor 3 NPR3 4883 NM_000908 /// NM_001204375 /// NM_001204376 /// NM_024563 /// XM_005248309 /// XM_005248310 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from sequence or structural similarity /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0030157 // pancreatic juice secretion // inferred from electronic annotation /// 0033688 // regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008528 // G-protein coupled peptide receptor activity // inferred from sequence or structural similarity /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from sequence or structural similarity /// 0042562 // hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 219790_s_at NM_000908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000908.1 /DEF=Homo sapiens natriuretic peptide receptor Cguanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), mRNA. /FEA=mRNA /GEN=NPR3 /PROD=natriuretic peptide receptor Cguanylate cyclaseC (atrionatriuretic peptide receptor C) /DB_XREF=gi:4505440 /UG=Hs.123655 natriuretic peptide receptor Cguanylate cyclase C (atrionatriuretic peptide receptor C) /FL=gb:M59305.1 gb:AF025998.1 gb:NM_000908.1 NM_000908 natriuretic peptide receptor 3 NPR3 4883 NM_000908 /// NM_001204375 /// NM_001204376 /// NM_024563 /// XM_005248309 /// XM_005248310 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0002158 // osteoclast proliferation // inferred from sequence or structural similarity /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0030157 // pancreatic juice secretion // inferred from electronic annotation /// 0033688 // regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008528 // G-protein coupled peptide receptor activity // inferred from sequence or structural similarity /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from sequence or structural similarity /// 0042562 // hormone binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 219791_s_at NM_024748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024748.1 /DEF=Homo sapiens hypothetical protein FLJ11539 (FLJ11539), mRNA. /FEA=mRNA /GEN=FLJ11539 /PROD=hypothetical protein FLJ11539 /DB_XREF=gi:13376075 /UG=Hs.125461 hypothetical protein FLJ11539 /FL=gb:NM_024748.1 NM_024748 HAND2 antisense RNA 1 (head to head) HAND2-AS1 79804 NR_003679 219792_at NM_024758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024758.1 /DEF=Homo sapiens hypothetical protein FLJ23384 (FLJ23384), mRNA. /FEA=mRNA /GEN=FLJ23384 /PROD=hypothetical protein FLJ23384 /DB_XREF=gi:13376094 /UG=Hs.127305 hypothetical protein FLJ23384 /FL=gb:NM_024758.1 gb:BC005090.1 NM_024758 agmatine ureohydrolase (agmatinase) AGMAT 79814 NM_024758 0006595 // polyamine metabolic process // traceable author statement /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from electronic annotation /// 0033388 // putrescine biosynthetic process from arginine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097055 // agmatine biosynthetic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008783 // agmatinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219793_at NM_022133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022133.1 /DEF=Homo sapiens sorting nexin 16 (SNX16), mRNA. /FEA=mRNA /GEN=SNX16 /PROD=sorting nexin 16 /DB_XREF=gi:11545864 /UG=Hs.128645 sorting nexin 16 /FL=gb:AF305779.1 gb:NM_022133.1 NM_022133 sorting nexin 16 SNX16 64089 NM_022133 /// NM_152836 /// NM_152837 /// XM_005251282 /// XM_005251283 /// XM_005251284 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031313 // extrinsic component of endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 219794_at NM_018289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018289.1 /DEF=Homo sapiens hypothetical protein FLJ10979 (FLJ10979), mRNA. /FEA=mRNA /GEN=FLJ10979 /PROD=hypothetical protein FLJ10979 /DB_XREF=gi:8922801 /UG=Hs.149797 hypothetical protein FLJ10979 /FL=gb:NM_018289.1 NM_018289 vacuolar protein sorting 53 homolog (S. cerevisiae) VPS53 55275 NM_001128159 /// NM_018289 /// XM_005256715 /// XM_005256716 /// XM_006721554 /// XM_006721555 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000938 // GARP complex // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219795_at NM_007231 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007231.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 14 (SLC6A14), mRNA. /FEA=mRNA /GEN=SLC6A14 /PROD=solute carrier family 6 (neurotransmittertransporter), member 14 /DB_XREF=gi:6005714 /UG=Hs.162211 solute carrier family 6 (neurotransmitter transporter), member 14 /FL=gb:AF151978.1 gb:NM_007231.1 NM_007231 solute carrier family 6 (amino acid transporter), member 14 SLC6A14 11254 NM_007231 0003333 // amino acid transmembrane transport // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 219796_s_at NM_021924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021924.1 /DEF=Homo sapiens mucin and cadherin-like (MUCDHL), mRNA. /FEA=mRNA /GEN=MUCDHL /PROD=mucin and cadherin-like /DB_XREF=gi:12313878 /UG=Hs.165619 mucin and cadherin-like /FL=gb:AF258676.1 gb:AF301909.1 gb:NM_021924.1 NM_021924 cadherin-related family member 5 CDHR5 53841 NM_001171968 /// NM_017717 /// NM_021924 /// NM_031264 /// NM_031265 /// XM_005252987 /// XM_005252988 /// XM_005252989 /// XM_005252990 /// XM_006718253 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008013 // beta-catenin binding // inferred from physical interaction 219797_at NM_012214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012214.1 /DEF=Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A (MGAT4A), mRNA. /FEA=mRNA /GEN=MGAT4A /PROD=mannosyl (alpha-1,3-)-glycoproteinbeta-1,4-N-acetylglucosaminyltransferase, isoenzyme A /DB_XREF=gi:6912501 /UG=Hs.177576 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A /FL=gb:AB000616.1 gb:NM_012214.1 NM_012214 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A MGAT4A 11320 NM_001160154 /// NM_012214 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008454 // alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219798_s_at NM_019606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019606.1 /DEF=Homo sapiens hypothetical protein FLJ20257 (FLJ20257), mRNA. /FEA=mRNA /GEN=FLJ20257 /PROD=hypothetical protein FLJ20257 /DB_XREF=gi:9624989 /UG=Hs.178011 hypothetical protein FLJ20257 /FL=gb:NM_019606.1 NM_019606 methylphosphate capping enzyme MEPCE 56257 NM_001194990 /// NM_001194991 /// NM_001194992 /// NM_019606 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001510 // RNA methylation // inferred from direct assay /// 0016073 // snRNA metabolic process // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0040031 // snRNA modification // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from direct assay /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219799_s_at NM_005771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005771.1 /DEF=Homo sapiens retinol dehydrogenase homolog (RDHL), mRNA. /FEA=mRNA /GEN=RDHL /PROD=retinol dehydrogenase homolog /DB_XREF=gi:5032034 /UG=Hs.179608 retinol dehydrogenase homolog /FL=gb:AF067174.1 gb:NM_005771.1 NM_005771 dehydrogenase/reductase (SDR family) member 9 DHRS9 10170 NM_001142270 /// NM_001142271 /// NM_001289763 /// NM_005771 /// NM_199204 /// XM_005246230 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008209 // androgen metabolic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // non-traceable author statement /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042572 // retinol metabolic process // non-traceable author statement /// 0042904 // 9-cis-retinoic acid biosynthetic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004022 // alcohol dehydrogenase (NAD) activity // inferred from direct assay /// 0004745 // retinol dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016854 // racemase and epimerase activity // non-traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from direct assay 219800_s_at NM_024838 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024838.1 /DEF=Homo sapiens hypothetical protein FLJ22002 (FLJ22002), mRNA. /FEA=mRNA /GEN=FLJ22002 /PROD=hypothetical protein FLJ22002 /DB_XREF=gi:13376250 /UG=Hs.183171 hypothetical protein FLJ22002 /FL=gb:NM_024838.1 NM_024838 threonine synthase-like 1 (S. cerevisiae) THNSL1 79896 NM_024838 /// XM_005252597 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 219801_at NM_030580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030580.1 /DEF=Homo sapiens hypothetical protein MGC10520 (MGC10520), mRNA. /FEA=mRNA /GEN=MGC10520 /PROD=hypothetical protein MGC10520 /DB_XREF=gi:13399331 /UG=Hs.191735 hypothetical protein MGC10520 /FL=gb:BC004480.1 gb:NM_030580.1 NM_030580 zinc finger protein 34 ZNF34 80778 NM_001286769 /// NM_001286770 /// NM_030580 /// XM_005272345 /// XM_005272346 /// XM_005272349 /// XM_006716662 /// XM_006716663 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219802_at NM_024854 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024854.1 /DEF=Homo sapiens hypothetical protein FLJ22028 (FLJ22028), mRNA. /FEA=mRNA /GEN=FLJ22028 /PROD=hypothetical protein FLJ22028 /DB_XREF=gi:13376278 /UG=Hs.192570 hypothetical protein FLJ22028 /FL=gb:NM_024854.1 NM_024854 pyridine nucleotide-disulphide oxidoreductase domain 1 PYROXD1 79912 NM_024854 /// XM_006719153 /// XR_242902 0055114 // oxidation-reduction process // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 219803_at NM_014495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014495.1 /DEF=Homo sapiens angiopoietin-like 3 (ANGPTL3), mRNA. /FEA=mRNA /GEN=ANGPTL3 /PROD=angiopoietin-like 3 precursor /DB_XREF=gi:7656887 /UG=Hs.209153 angiopoietin-like 3 /FL=gb:AF152562.1 gb:NM_014495.1 NM_014495 angiopoietin-like 3 ANGPTL3 27329 NM_014495 0006071 // glycerol metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from physical interaction /// 0007165 // signal transduction // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0009725 // response to hormone // inferred from electronic annotation /// 0010519 // negative regulation of phospholipase activity // inferred from direct assay /// 0019915 // lipid storage // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050996 // positive regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay /// 0055088 // lipid homeostasis // inferred from direct assay /// 0055090 // acylglycerol homeostasis // inferred from direct assay /// 0055091 // phospholipid homeostasis // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from genetic interaction /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 219804_at NM_024875 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024875.1 /DEF=Homo sapiens hypothetical protein FLJ12921 (FLJ12921), mRNA. /FEA=mRNA /GEN=FLJ12921 /PROD=hypothetical protein FLJ12921 /DB_XREF=gi:13376313 /UG=Hs.209637 hypothetical protein FLJ12921 /FL=gb:NM_024875.1 NM_024875 synaptopodin 2-like SYNPO2L 79933 NM_001114133 /// NM_024875 /// XM_005270158 /// XM_005270159 /// XM_005270160 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219805_at NM_022101 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022101.1 /DEF=Homo sapiens hypothetical protein FLJ22965 (FLJ22965), mRNA. /FEA=mRNA /GEN=FLJ22965 /PROD=hypothetical protein FLJ22965 /DB_XREF=gi:11545812 /UG=Hs.248572 hypothetical protein FLJ22965 /FL=gb:NM_022101.1 NM_022101 chromosome X open reading frame 56 CXorf56 63932 NM_001170569 /// NM_001170570 /// NM_022101 219806_s_at NM_020179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020179.1 /DEF=Homo sapiens FN5 protein (FN5), mRNA. /FEA=mRNA /GEN=FN5 /PROD=FN5 protein /DB_XREF=gi:9910225 /UG=Hs.259737 FN5 protein /FL=gb:AF197137.1 gb:NM_020179.1 NM_020179 single-pass membrane protein with coiled-coil domains 4 SMCO4 56935 NM_020179 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219807_x_at NM_016154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016154.1 /DEF=Homo sapiens ras-related GTP-binding protein 4b (RAB4B), mRNA. /FEA=mRNA /GEN=RAB4B /PROD=ras-related GTP-binding protein 4b /DB_XREF=gi:7706672 /UG=Hs.279771 Homo sapiens TR00071289_m (RAB4B), mRNA /FL=gb:AF165522.1 gb:NM_016154.1 NM_016154 MIA-RAB4B readthrough (NMD candidate) /// RAB4B, member RAS oncogene family MIA-RAB4B /// RAB4B 53916 /// 100529262 NM_016154 /// NR_037775 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046323 // glucose import // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032593 // insulin-responsive compartment // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219808_at NM_016510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016510.1 /DEF=Homo sapiens putative selenocysteine lyase (SCLY), mRNA. /FEA=mRNA /GEN=SCLY /PROD=putative selenocysteine lyase /DB_XREF=gi:7706696 /UG=Hs.285306 putative selenocysteine lyase /FL=gb:AF175767.1 gb:NM_016510.1 NM_016510 selenocysteine lyase SCLY 51540 NM_016510 0006520 // cellular amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0009000 // selenocysteine lyase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 219809_at NM_017706 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017706.1 /DEF=Homo sapiens hypothetical protein FLJ20195 (FLJ20195), mRNA. /FEA=mRNA /GEN=FLJ20195 /PROD=hypothetical protein FLJ20195 /DB_XREF=gi:8923184 /UG=Hs.286261 hypothetical protein FLJ20195 /FL=gb:NM_017706.1 NM_017706 WD repeat domain 55 WDR55 54853 NM_017706 /// XM_005268469 /// XM_005268471 /// XM_006714788 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0060965 // negative regulation of gene silencing by miRNA // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from direct assay 219810_at NM_025054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025054.1 /DEF=Homo sapiens hypothetical protein FLJ23132 (FLJ23132), mRNA. /FEA=mRNA /GEN=FLJ23132 /PROD=hypothetical protein FLJ23132 /DB_XREF=gi:13376584 /UG=Hs.287727 hypothetical protein FLJ23132 /FL=gb:NM_025054.1 NM_025054 valosin containing protein (p97)/p47 complex interacting protein 1 VCPIP1 80124 NM_025054 0006508 // proteolysis // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016320 // endoplasmic reticulum membrane fusion // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0090168 // Golgi reassembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219811_at NM_022720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022720.1 /DEF=Homo sapiens DiGeorge syndrome critical region gene 8 (DGCR8), mRNA. /FEA=mRNA /GEN=DGCR8 /PROD=DiGeorge syndrome critical region gene 8 /DB_XREF=gi:12225241 /UG=Hs.301855 DiGeorge syndrome critical region gene 8 /FL=gb:NM_022720.1 gb:AF165527.1 NM_022720 DGCR8 microprocessor complex subunit /// microRNA 1306 DGCR8 /// MIR1306 54487 /// 100302197 NM_001190326 /// NM_022720 /// NR_031706 /// XM_006724268 0010467 // gene expression // traceable author statement /// 0031053 // primary miRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219812_at NM_024070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024070.1 /DEF=Homo sapiens hypothetical protein MGC2463 (MGC2463), mRNA. /FEA=mRNA /GEN=MGC2463 /PROD=hypothetical protein MGC2463 /DB_XREF=gi:13129051 /UG=Hs.323634 hypothetical protein MGC2463 /FL=gb:BC001129.1 gb:NM_024070.1 NM_024070 poliovirus receptor related immunoglobulin domain containing PVRIG 79037 NM_024070 /// XM_006716125 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000795 // synaptonemal complex // traceable author statement /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0000802 // transverse filament // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030893 // meiotic cohesin complex // inferred from direct assay /// 0030893 // meiotic cohesin complex // inferred from electronic annotation 219813_at NM_004690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004690.2 /DEF=Homo sapiens LATS (large tumor suppressor, Drosophila) homolog 1 (LATS1), mRNA. /FEA=mRNA /GEN=LATS1 /PROD=LATS (large tumor suppressor, Drosophila)homolog 1 /DB_XREF=gi:10862687 /UG=Hs.324925 LATS (large tumor suppressor, Drosophila) homolog 1 /FL=gb:NM_004690.2 gb:AF104413.1 gb:AF164041.1 NM_004690 large tumor suppressor kinase 1 LATS1 9113 NM_001270519 /// NM_004690 /// NR_073033 /// XM_006715603 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000819 // sister chromatid segregation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0043254 // regulation of protein complex assembly // inferred from mutant phenotype /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219814_at NM_018388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018388.1 /DEF=Homo sapiens hypothetical protein FLJ11316 (FLJ11316), mRNA. /FEA=mRNA /GEN=FLJ11316 /PROD=hypothetical protein FLJ11316 /DB_XREF=gi:8922990 /UG=Hs.35225 hypothetical protein FLJ11316 /FL=gb:NM_018388.1 NM_018388 muscleblind-like splicing regulator 3 MBNL3 55796 NM_001170701 /// NM_001170702 /// NM_001170703 /// NM_001170704 /// NM_018388 /// NM_133486 /// XM_005262431 /// XM_005262432 /// XM_005262433 /// XM_005262434 /// XM_005262435 /// XM_005262436 /// XM_005262437 /// XM_005262438 /// XM_005262439 /// XM_005262440 /// XM_005262441 /// XM_005262442 /// XM_006724766 0006397 // mRNA processing // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219815_at NM_024637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024637.1 /DEF=Homo sapiens hypothetical protein FLJ12116 (FLJ12116), mRNA. /FEA=mRNA /GEN=FLJ12116 /PROD=hypothetical protein FLJ12116 /DB_XREF=gi:13375869 /UG=Hs.44856 hypothetical protein FLJ12116 /FL=gb:NM_024637.1 NM_024637 galactose-3-O-sulfotransferase 4 GAL3ST4 79690 NM_024637 0006790 // sulfur compound metabolic process // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // non-traceable author statement /// 0009311 // oligosaccharide metabolic process // non-traceable author statement /// 0030166 // proteoglycan biosynthetic process // non-traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001733 // galactosylceramide sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // non-traceable author statement /// 0050694 // galactose 3-O-sulfotransferase activity // inferred from direct assay /// 0050698 // proteoglycan sulfotransferase activity // non-traceable author statement 219816_s_at NM_018107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018107.1 /DEF=Homo sapiens hypothetical protein FLJ10482 (FLJ10482), mRNA. /FEA=mRNA /GEN=FLJ10482 /PROD=hypothetical protein FLJ10482 /DB_XREF=gi:8922449 /UG=Hs.4997 hypothetical protein FLJ10482 /FL=gb:NM_018107.1 NM_018107 RNA binding motif protein 23 RBM23 55147 NM_001077351 /// NM_001077352 /// NM_018107 /// XM_005267797 /// XM_005267798 /// XM_005267799 /// XM_005267800 /// XM_005267801 /// XM_005267802 /// XM_005267803 /// XR_245698 0006397 // mRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219817_at NM_016534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016534.1 /DEF=Homo sapiens apoptosis-related protein PNAS-1 (LOC51275), mRNA. /FEA=mRNA /GEN=LOC51275 /PROD=apoptosis-related protein PNAS-1 /DB_XREF=gi:7706078 /UG=Hs.52166 apoptosis-related protein PNAS-1 /FL=gb:AF229831.1 gb:NM_016534.1 NM_016534 MAPKAPK5 antisense RNA 1 MAPKAPK5-AS1 51275 NM_016534 /// NR_015404 219818_s_at NM_018025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018025.1 /DEF=Homo sapiens hypothetical protein FLJ10206 (FLJ10206), mRNA. /FEA=mRNA /GEN=FLJ10206 /PROD=hypothetical protein FLJ10206 /DB_XREF=gi:8922282 /UG=Hs.55014 hypothetical protein FLJ10206 /FL=gb:NM_018025.1 NM_018025 G patch domain containing 1 GPATCH1 55094 NM_018025 /// XM_006723255 0000398 // mRNA splicing, via spliceosome // inferred by curator 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation 219819_s_at NM_014018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014018.1 /DEF=Homo sapiens HSPC007 protein (HSPC007), mRNA. /FEA=mRNA /GEN=HSPC007 /PROD=HSPC007 protein /DB_XREF=gi:7661729 /UG=Hs.55097 HSPC007 protein /FL=gb:AF070663.1 gb:NM_014018.1 NM_014018 mitochondrial ribosomal protein S28 MRPS28 28957 NM_014018 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 219820_at NM_014037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014037.1 /DEF=Homo sapiens NTT5 protein (NTT5), mRNA. /FEA=mRNA /GEN=NTT5 /PROD=NTT5 protein /DB_XREF=gi:7662517 /UG=Hs.59260 NTT5 protein /FL=gb:AF265578.1 gb:AL136856.1 gb:AF151977.1 gb:NM_014037.1 NM_014037 solute carrier family 6, member 16 SLC6A16 28968 NM_014037 /// XM_005258819 /// XM_005258820 /// XM_006723168 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005326 // neurotransmitter transporter activity // non-traceable author statement /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 219821_s_at NM_018988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018988.1 /DEF=Homo sapiens hypothetical protein (FLJ20330), mRNA. /FEA=mRNA /GEN=FLJ20330 /PROD=hypothetical protein /DB_XREF=gi:9506674 /UG=Hs.61485 hypothetical protein /FL=gb:NM_018988.1 NM_018988 glucose-fructose oxidoreductase domain containing 1 GFOD1 54438 NM_001242628 /// NM_001242629 /// NM_001242630 /// NM_018988 /// NM_033069 /// NR_038459 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 219822_at NM_004294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004294.1 /DEF=Homo sapiens mitochondrial translational release factor 1 (MTRF1), mRNA. /FEA=mRNA /GEN=MTRF1 /PROD=mitochondrial translational release factor 1 /DB_XREF=gi:4758743 /UG=Hs.80683 mitochondrial translational release factor 1 /FL=gb:AF072934.1 gb:NM_004294.1 NM_004294 mitochondrial translational release factor 1 MTRF1 9617 NM_004294 /// XM_005266599 /// XM_006719897 /// XM_006719898 /// XM_006719899 /// XM_006719900 /// XM_006719901 /// XR_429224 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation /// 0006449 // regulation of translational termination // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003747 // translation release factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation 219823_at NM_024674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024674.1 /DEF=Homo sapiens hypothetical protein FLJ12457 (FLJ12457), mRNA. /FEA=mRNA /GEN=FLJ12457 /PROD=hypothetical protein FLJ12457 /DB_XREF=gi:13375937 /UG=Hs.86154 hypothetical protein FLJ12457 /FL=gb:NM_024674.1 NM_024674 lin-28 homolog A (C. elegans) LIN28A 79727 NM_024674 /// XM_006710899 /// XM_006710900 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0010586 // miRNA metabolic process // inferred from electronic annotation /// 0010587 // miRNA catabolic process // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from mutant phenotype /// 0031123 // RNA 3'-end processing // inferred from mutant phenotype /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045686 // negative regulation of glial cell differentiation // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0060964 // regulation of gene silencing by miRNA // inferred from electronic annotation 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0035198 // miRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219824_at NM_012450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012450.1 /DEF=Homo sapiens sulfate transporter 1 (SUT1), mRNA. /FEA=mRNA /GEN=SUT1 /PROD=sulfate transporter 1 /DB_XREF=gi:6912689 /UG=Hs.9098 sulfate transporter 1 /FL=gb:AF169301.1 gb:NM_012450.1 NM_012450 solute carrier family 13 (sodium/sulfate symporter), member 4 SLC13A4 26266 NM_012450 /// XM_005250261 /// XM_005250262 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008272 // sulfate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015382 // sodium:sulfate symporter activity // traceable author statement 219825_at NM_019885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019885.1 /DEF=Homo sapiens cytochrome P450 retinoid metabolizing protein (P450RAI-2), mRNA. /FEA=mRNA /GEN=P450RAI-2 /PROD=cytochrome P450 retinoid metabolizing protein /DB_XREF=gi:9845284 /UG=Hs.91546 cytochrome P450 retinoid metabolizing protein /FL=gb:AF252297.1 gb:NM_019885.1 NM_019885 cytochrome P450, family 26, subfamily B, polypeptide 1 CYP26B1 56603 NM_001277742 /// NM_019885 /// XM_005264433 0001709 // cell fate determination // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0009954 // proximal/distal pattern formation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0034653 // retinoic acid catabolic process // inferred from direct assay /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation /// 0043587 // tongue morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060349 // bone morphogenesis // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 2001037 // positive regulation of tongue muscle cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0001972 // retinoic acid binding // inferred from direct assay /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008401 // retinoic acid 4-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219826_at NM_024691 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024691.1 /DEF=Homo sapiens hypothetical protein FLJ23233 (FLJ23233), mRNA. /FEA=mRNA /GEN=FLJ23233 /PROD=hypothetical protein FLJ23233 /DB_XREF=gi:13375967 /UG=Hs.98593 hypothetical protein FLJ23233 /FL=gb:NM_024691.1 NM_024691 zinc finger protein 419 ZNF419 79744 NM_001098491 /// NM_001098492 /// NM_001098493 /// NM_001098494 /// NM_001098495 /// NM_001098496 /// NM_001291743 /// NM_001291744 /// NM_001291745 /// NM_024691 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219827_at NM_003356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003356.2 /DEF=Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant long, nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=UCP3 /PROD=uncoupling protein 3, isoform UCP3L /DB_XREF=gi:13259544 /UG=Hs.101337 uncoupling protein 3 (mitochondrial, proton carrier) /FL=gb:NM_003356.2 gb:U84763.1 gb:AF001787.1 gb:AF011449.1 NM_003356 uncoupling protein 3 (mitochondrial, proton carrier) UCP3 7352 NM_003356 /// NM_022803 0000303 // response to superoxide // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017077 // oxidative phosphorylation uncoupler activity // inferred from electronic annotation 219828_at NM_024718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024718.1 /DEF=Homo sapiens hypothetical protein FLJ10101 (FLJ10101), mRNA. /FEA=mRNA /GEN=FLJ10101 /PROD=hypothetical protein FLJ13045 /DB_XREF=gi:13435142 /UG=Hs.108115 hypothetical protein FLJ10101 /FL=gb:NM_024718.1 NM_024718 RAB, member RAS oncogene family-like 6 RABL6 55684 NM_001173988 /// NM_001173989 /// NM_017995 /// NM_024718 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 219829_at NM_012278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012278.1 /DEF=Homo sapiens integrin beta 1 binding protein (melusin) 2 (ITGB1BP2), mRNA. /FEA=mRNA /GEN=ITGB1BP2 /PROD=integrin beta 1 binding protein (melusin) 2 /DB_XREF=gi:6912437 /UG=Hs.109999 integrin beta 1 binding protein (melusin) 2 /FL=gb:AF140690.1 gb:NM_012278.1 NM_012278 integrin beta 1 binding protein (melusin) 2 ITGB1BP2 26548 NM_012278 /// XM_005262255 0007165 // signal transduction // traceable author statement /// 0007517 // muscle organ development // traceable author statement 0030018 // Z disc // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219830_at NM_030665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030665.1 /DEF=Homo sapiens retinoic acid induced 1 (RAI1), mRNA. /FEA=mRNA /GEN=RAI1 /PROD=retinoic acid induced 1 /DB_XREF=gi:13489059 /UG=Hs.110953 retinoic acid induced 1 /FL=gb:NM_030665.1 NM_030665 retinoic acid induced 1 RAI1 10743 NM_030665 0001501 // skeletal system development // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from mutant phenotype /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0035326 // enhancer binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 219831_at NM_016508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016508.1 /DEF=Homo sapiens serine-threonine protein kinase NKIAMRE (LOC51265), mRNA. /FEA=mRNA /GEN=LOC51265 /PROD=serine-threonine protein kinase NKIAMRE /DB_XREF=gi:7706058 /UG=Hs.118508 cyclin-dependent kinase-like 3 /FL=gb:AF130372.1 gb:NM_016508.1 NM_016508 cyclin-dependent kinase-like 3 CDKL3 51265 NM_001113575 /// NM_016508 /// XM_005272004 /// XM_006714642 /// XM_006714643 /// XM_006714644 /// XM_006714645 /// XM_006714646 /// XR_427712 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219832_s_at NM_017410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017410.1 /DEF=Homo sapiens homeo box C13 (HOXC13), mRNA. /FEA=mRNA /GEN=HOXC13 /PROD=homeo box C13 /DB_XREF=gi:8393553 /UG=Hs.118608 homeo box C13 /FL=gb:AF255676.1 gb:NM_017410.1 gb:AF263466.2 NM_017410 homeobox C13 HOXC13 3229 NM_017410 0001942 // hair follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0035878 // nail development // inferred from electronic annotation /// 0043587 // tongue morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 219833_s_at NM_018100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018100.1 /DEF=Homo sapiens hypothetical protein FLJ10466 (FLJ10466), mRNA. /FEA=mRNA /GEN=FLJ10466 /PROD=hypothetical protein FLJ10466 /DB_XREF=gi:8922435 /UG=Hs.121073 hypothetical protein FLJ10466 /FL=gb:NM_018100.1 NM_018100 EF-hand domain (C-terminal) containing 1 EFHC1 114327 NM_001172420 /// NM_018100 /// NR_033327 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity 219834_at NM_024744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024744.1 /DEF=Homo sapiens hypothetical protein FLJ21579 (FLJ21579), mRNA. /FEA=mRNA /GEN=FLJ21579 /PROD=hypothetical protein FLJ21579 /DB_XREF=gi:13376067 /UG=Hs.122970 hypothetical protein FLJ21579 /FL=gb:NM_024744.1 NM_024744 calcium responsive transcription factor CARF 79800 NM_001104586 /// NM_001282910 /// NM_001282911 /// NM_001282912 /// NM_024744 /// XM_005246858 /// XM_005246859 /// XM_005246860 /// XM_005246863 /// XM_005246864 /// XM_006712757 /// XM_006712758 /// XM_006712759 /// XM_006712760 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035865 // cellular response to potassium ion // inferred from direct assay /// 0061400 // positive regulation of transcription from RNA polymerase II promoter in response to calcium ion // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay 219835_at NM_020226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020226.1 /DEF=Homo sapiens PR domain containing 8 (PRDM8), mRNA. /FEA=mRNA /GEN=PRDM8 /PROD=PR domain containing 8 /DB_XREF=gi:9910507 /UG=Hs.134503 PR domain containing 8 /FL=gb:AF275815.1 gb:NM_020226.1 NM_020226 PR domain containing 8 PRDM8 56978 NM_001099403 /// NM_020226 /// XM_005263143 /// XM_005263144 /// XM_005263145 /// XM_005263146 /// XM_006714279 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0021540 // corpus callosum morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021957 // corticospinal tract morphogenesis // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042054 // histone methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from electronic annotation 219836_at NM_024508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024508.1 /DEF=Homo sapiens hypothetical protein MGC10796 (MGC10796), mRNA. /FEA=mRNA /GEN=MGC10796 /PROD=hypothetical protein MGC10796 /DB_XREF=gi:13375643 /UG=Hs.136912 hypothetical protein MGC10796 /FL=gb:BC003536.1 gb:NM_024508.1 NM_024508 zinc finger, BED-type containing 2 ZBED2 79413 NM_024508 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219837_s_at NM_018659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018659.1 /DEF=Homo sapiens cytokine-like protein C17 (C17), mRNA. /FEA=mRNA /GEN=C17 /PROD=cytokine-like protein C17 /DB_XREF=gi:8922107 /UG=Hs.13872 cytokine-like protein C17 /FL=gb:AF193766.1 gb:NM_018659.1 NM_018659 cytokine-like 1 CYTL1 54360 NM_018659 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 1990079 // cartilage homeostasis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // traceable author statement 219838_at NM_022905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022905.1 /DEF=Homo sapiens hypothetical protein FLJ12572 (FLJ12572), mRNA. /FEA=mRNA /GEN=FLJ12572 /PROD=hypothetical protein FLJ12572 /DB_XREF=gi:12597646 /UG=Hs.139709 hypothetical protein FLJ12572 /FL=gb:NM_022905.1 NM_022905 tetratricopeptide repeat domain 23 TTC23 64927 NM_001040655 /// NM_001040656 /// NM_001040657 /// NM_001040658 /// NM_001040659 /// NM_001040660 /// NM_001288615 /// NM_001288616 /// NM_022905 /// NR_109947 /// XM_005254969 /// XM_005254970 /// XM_005254971 /// XM_005254972 /// XM_005254973 /// XM_006720647 /// XM_006720648 /// XM_006720649 /// XM_006720650 0005515 // protein binding // inferred from electronic annotation 219839_x_at NM_012468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012468.2 /DEF=Homo sapiens T-cell leukemialymphoma 6 (TCL6), transcript variant TCL6a1, mRNA. /FEA=mRNA /GEN=TCL6 /PROD=T-cell leukemialymphoma 6, isoform TCL6a1 /DB_XREF=gi:10947106 /UG=Hs.144519 T-cell leukemialymphoma 6 /FL=gb:NM_012468.2 gb:AF195820.1 gb:AB035332.1 NM_012468 T-cell leukemia/lymphoma 6 (non-protein coding) TCL6 27004 NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NR_028288 219840_s_at AF195820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF195820.1 /DEF=Homo sapiens Tng1 (TNG1) mRNA, complete cds. /FEA=mRNA /GEN=TNG1 /PROD=Tng1 /DB_XREF=gi:6319191 /UG=Hs.144519 T-cell leukemialymphoma 6 /FL=gb:NM_012468.2 gb:AF195820.1 gb:AB035332.1 AF195820 T-cell leukemia/lymphoma 6 (non-protein coding) TCL6 27004 NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NR_028288 219841_at NM_020661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020661.1 /DEF=Homo sapiens activation-induced cytidine deaminase (AICDA), mRNA. /FEA=mRNA /GEN=AICDA /PROD=activation-induced cytidine deaminase /DB_XREF=gi:10190699 /UG=Hs.149342 activation-induced cytidine deaminase /FL=gb:NM_020661.1 gb:AB040431.1 NM_020661 activation-induced cytidine deaminase AICDA 57379 NM_020661 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from electronic annotation /// 0016445 // somatic diversification of immunoglobulins // inferred from direct assay /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from mutant phenotype /// 0030183 // B cell differentiation // non-traceable author statement /// 0045190 // isotype switching // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0080111 // DNA demethylation // inferred from direct assay /// 0090310 // negative regulation of methylation-dependent chromatin silencing // inferred from direct assay 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // inferred from direct assay /// 0004126 // cytidine deaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219842_at NM_019087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019087.1 /DEF=Homo sapiens hypothetical protein FLJ20051 (FLJ20051), mRNA. /FEA=mRNA /GEN=FLJ20051 /PROD=hypothetical protein FLJ20051 /DB_XREF=gi:9506652 /UG=Hs.152664 hypothetical protein FLJ20051 /FL=gb:NM_019087.1 NM_019087 ADP-ribosylation factor-like 15 ARL15 54622 NM_019087 /// XM_005248549 /// XM_005248550 /// XM_006714654 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 219843_at NM_005897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005897.1 /DEF=Homo sapiens intracisternal A particle-promoted polypeptide (IPP), mRNA. /FEA=mRNA /GEN=IPP /PROD=intracisternal A particle-promoted polypeptide /DB_XREF=gi:5174472 /UG=Hs.157180 intracisternal A particle-promoted polypeptide /FL=gb:AF156857.1 gb:NM_005897.1 NM_005897 intracisternal A particle-promoted polypeptide IPP 3652 NM_001145349 /// NM_005897 /// XM_005270839 /// XM_005270840 /// XM_006710622 /// XM_006710623 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219844_at NM_018017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018017.1 /DEF=Homo sapiens hypothetical protein FLJ10188 (FLJ10188), mRNA. /FEA=mRNA /GEN=FLJ10188 /PROD=hypothetical protein FLJ10188 /DB_XREF=gi:8922268 /UG=Hs.159066 hypothetical protein FLJ10188 /FL=gb:NM_018017.1 NM_018017 coiled-coil domain containing 186 CCDC186 55088 NM_018017 /// XM_005269937 219845_at NM_021570 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021570.2 /DEF=Homo sapiens BarH-like homeobox 1 (BARX1), mRNA. /FEA=mRNA /GEN=BARX1 /PROD=BarH-like homeobox 1 /DB_XREF=gi:13386501 /UG=Hs.164960 BarH-like homeobox 1 /FL=gb:AF213356.1 gb:NM_021570.2 NM_021570 BARX homeobox 1 BARX1 56033 NM_021570 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009888 // tissue development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0055123 // digestive system development // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 219846_at NM_025174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025174.1 /DEF=Homo sapiens hypothetical protein FLJ23040 (FLJ23040), mRNA. /FEA=mRNA /GEN=FLJ23040 /PROD=hypothetical protein FLJ23040 /DB_XREF=gi:13376769 /UG=Hs.169813 hypothetical protein FLJ23040 /FL=gb:NM_025174.1 NM_025174 gon-4-like (C. elegans) GON4L 54856 NM_001037533 /// NM_001282856 /// NM_001282858 /// NM_001282860 /// NM_001282861 /// NM_032292 /// XM_005245283 /// XM_005245284 /// XM_005245286 /// XM_006711393 /// XM_006711394 /// XM_006711395 /// XM_006711396 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 219847_at NM_024827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024827.1 /DEF=Homo sapiens hypothetical protein FLJ22237 (FLJ22237), mRNA. /FEA=mRNA /GEN=FLJ22237 /PROD=hypothetical protein FLJ22237 /DB_XREF=gi:13376227 /UG=Hs.177956 hypothetical protein FLJ22237 /FL=gb:NM_024827.1 NM_024827 histone deacetylase 11 HDAC11 79885 NM_001136041 /// NM_024827 /// XM_005265491 /// XM_005265492 /// XM_005265493 /// XM_006713338 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from direct assay /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 219848_s_at NM_014650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014650.1 /DEF=Homo sapiens KIAA0798 gene product (KIAA0798), mRNA. /FEA=mRNA /GEN=KIAA0798 /PROD=KIAA0798 gene product /DB_XREF=gi:7662313 /UG=Hs.178471 KIAA0798 gene product /FL=gb:BC002858.1 gb:AB018341.1 gb:NM_014650.1 NM_014650 zinc finger protein 432 ZNF432 9668 NM_014650 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219849_at NM_024833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024833.1 /DEF=Homo sapiens hypothetical protein FLJ23506 (FLJ23506), mRNA. /FEA=mRNA /GEN=FLJ23506 /PROD=hypothetical protein FLJ23506 /DB_XREF=gi:13376239 /UG=Hs.180402 hypothetical protein FLJ23506 /FL=gb:NM_024833.1 NM_024833 zinc finger protein 671 ZNF671 79891 NM_024833 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219850_s_at NM_012153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012153.1 /DEF=Homo sapiens Ets homologous factor (EHF), mRNA. /FEA=mRNA /GEN=EHF /PROD=ets homologous factor /DB_XREF=gi:6912349 /UG=Hs.182339 ets homologous factor /FL=gb:AF203977.1 gb:AF124439.1 gb:AF170583.1 gb:NM_012153.1 gb:AF212848.1 NM_012153 ets homologous factor EHF 26298 NM_001206615 /// NM_001206616 /// NM_012153 /// XM_005252857 /// XM_005252858 /// XM_005252860 /// XM_005252861 /// XM_005252862 /// XM_006718176 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred by curator 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 219851_at NM_024840 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024840.1 /DEF=Homo sapiens hypothetical protein FLJ13590 (FLJ13590), mRNA. /FEA=mRNA /GEN=FLJ13590 /PROD=hypothetical protein FLJ13590 /DB_XREF=gi:13430869 /UG=Hs.183390 hypothetical protein FLJ13590 /FL=gb:NM_024840.1 NM_024840 zinc finger protein 613 ZNF613 79898 NM_001031721 /// NM_024840 /// XM_005259269 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219852_s_at NM_024848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024848.1 /DEF=Homo sapiens hypothetical protein FLJ13941 (FLJ13941), mRNA. /FEA=mRNA /GEN=FLJ13941 /PROD=hypothetical protein FLJ13941 /DB_XREF=gi:13376266 /UG=Hs.187617 hypothetical protein FLJ13941 /FL=gb:NM_024848.1 NM_024848 MORN repeat containing 1 MORN1 79906 NM_024848 /// XM_005244798 /// XM_005244799 /// XM_006710906 219853_at NM_024301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024301.1 /DEF=Homo sapiens hypothetical protein MGC2991 (MGC2991), mRNA. /FEA=mRNA /GEN=MGC2991 /PROD=hypothetical protein MGC2991 /DB_XREF=gi:13236527 /UG=Hs.193261 hypothetical protein MGC2991 /FL=gb:BC002612.1 gb:NM_024301.1 NM_024301 fukutin related protein FKRP 79147 NM_001039885 /// NM_024301 /// XM_005259247 /// XM_005259248 /// XM_005259249 /// XM_005259250 /// XM_006723373 /// XM_006723374 /// XM_006723375 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation 219854_at NM_021030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021030.1 /DEF=Homo sapiens zinc finger protein 14 (KOX 6) (ZNF14), mRNA. /FEA=mRNA /GEN=ZNF14 /PROD=zinc finger protein 14 (KOX 6) /DB_XREF=gi:11139306 /UG=Hs.197219 zinc finger protein 14 (KOX 6) /FL=gb:NM_021030.1 gb:AB021644.1 NM_021030 zinc finger protein 14 ZNF14 7561 NM_021030 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 219855_at NM_018159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018159.1 /DEF=Homo sapiens hypothetical protein FLJ10628 (FLJ10628), mRNA. /FEA=mRNA /GEN=FLJ10628 /PROD=hypothetical protein FLJ10628 /DB_XREF=gi:8922558 /UG=Hs.200016 hypothetical protein FLJ10628 /FL=gb:NM_018159.1 NM_018159 nudix (nucleoside diphosphate linked moiety X)-type motif 11 NUDT11 55190 NM_018159 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 219856_at NM_023938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023938.1 /DEF=Homo sapiens hypothetical protein MGC2742 (MGC2742), mRNA. /FEA=mRNA /GEN=MGC2742 /PROD=hypothetical protein MGC2742 /DB_XREF=gi:13027607 /UG=Hs.223394 hypothetical protein MGC2742 /FL=gb:BC000765.1 gb:NM_023938.1 NM_023938 chromosome 1 open reading frame 116 C1orf116 79098 NM_001083924 /// NM_023938 /// XM_005273259 /// XM_006711530 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 219857_at NM_024889 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024889.1 /DEF=Homo sapiens hypothetical protein FLJ23537 (FLJ23537), mRNA. /FEA=mRNA /GEN=FLJ23537 /PROD=hypothetical protein FLJ23537 /DB_XREF=gi:13376340 /UG=Hs.228320 hypothetical protein FLJ23537 /FL=gb:NM_024889.1 NM_024889 pleckstrin homology domain containing, family S member 1 PLEKHS1 79949 NM_001193434 /// NM_001193435 /// NM_024889 /// NM_182601 /// XM_005270162 /// XM_005270163 219858_s_at NM_017694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017694.1 /DEF=Homo sapiens hypothetical protein FLJ20160 (FLJ20160), mRNA. /FEA=mRNA /GEN=FLJ20160 /PROD=hypothetical protein FLJ20160 /DB_XREF=gi:8923159 /UG=Hs.23412 hypothetical protein FLJ20160 /FL=gb:NM_017694.1 NM_017694 major facilitator superfamily domain containing 6 MFSD6 54842 NM_017694 /// XM_005246654 /// XM_005246655 /// XM_005246656 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219859_at NM_014358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014358.1 /DEF=Homo sapiens C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9 (CLECSF9), mRNA. /FEA=mRNA /GEN=CLECSF9 /PROD=C-type (calcium dependent,carbohydrate-recognition domain) lectin, superfamilymember 9 /DB_XREF=gi:7657332 /UG=Hs.236516 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9 /FL=gb:BC000715.1 gb:AB024718.1 gb:NM_014358.1 NM_014358 C-type lectin domain family 4, member E CLEC4E 26253 NM_014358 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219860_at NM_025262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025262.1 /DEF=Homo sapiens G5C protein (G5C), mRNA. /FEA=mRNA /GEN=G5C /PROD=G5C protein /DB_XREF=gi:13376875 /UG=Hs.246845 G5C protein /FL=gb:NM_025262.1 NM_025262 lymphocyte antigen 6 complex, locus G5C LY6G5C 80741 NM_001002848 /// NM_001002849 /// NM_025262 0005576 // extracellular region // inferred from electronic annotation 219861_at NM_018163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018163.1 /DEF=Homo sapiens hypothetical protein FLJ10634 (FLJ10634), mRNA. /FEA=mRNA /GEN=FLJ10634 /PROD=hypothetical protein FLJ10634 /DB_XREF=gi:8922562 /UG=Hs.24989 hypothetical protein FLJ10634 /FL=gb:BC000048.1 gb:NM_018163.1 NM_018163 DnaJ (Hsp40) homolog, subfamily C, member 17 DNAJC17 55192 NM_018163 /// XM_005254533 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 219862_s_at NM_012336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012336.1 /DEF=Homo sapiens nuclear prelamin A recognition factor (NARF), mRNA. /FEA=mRNA /GEN=NARF /PROD=nuclear prelamin A recognition factor /DB_XREF=gi:6912523 /UG=Hs.256526 nuclear prelamin A recognition factor /FL=gb:AF128406.1 gb:NM_012336.1 NM_012336 nuclear prelamin A recognition factor NARF 26502 NM_001038618 /// NM_001083608 /// NM_012336 /// NM_031968 /// XM_005256340 /// XM_006722278 0005634 // nucleus // inferred from direct assay /// 0005638 // lamin filament // inferred from direct assay /// 0005652 // nuclear lamina // traceable author statement /// 0031981 // nuclear lumen // inferred from direct assay 0005521 // lamin binding // inferred from physical interaction 219863_at NM_016323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016323.1 /DEF=Homo sapiens cyclin-E binding protein 1 (LOC51191), mRNA. /FEA=mRNA /GEN=LOC51191 /PROD=cyclin-E binding protein 1 /DB_XREF=gi:7705930 /UG=Hs.26663 cyclin-E binding protein 1 /FL=gb:AB027289.1 gb:NM_016323.1 NM_016323 HECT and RLD domain containing E3 ubiquitin protein ligase 5 HERC5 51191 NM_016323 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0045087 // innate immune response // traceable author statement /// 0050688 // regulation of defense response to virus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0042296 // ISG15 ligase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 219864_s_at NM_013441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013441.1 /DEF=Homo sapiens Down syndrome critical region gene 1-like 2 (DSCR1L2), mRNA. /FEA=mRNA /GEN=DSCR1L2 /PROD=Down syndrome critical region gene 1-like 2protein /DB_XREF=gi:7305008 /UG=Hs.274131 Down syndrome critical region gene 1-like 2 /FL=gb:AF176116.1 gb:NM_013441.1 NM_013441 RCAN family member 3 RCAN3 11123 NM_001251977 /// NM_001251978 /// NM_001251979 /// NM_001251980 /// NM_001251981 /// NM_001251982 /// NM_001251983 /// NM_001251984 /// NM_001251985 /// NM_013441 0009653 // anatomical structure morphogenesis // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0031013 // troponin I binding // inferred from physical interaction 219865_at NM_014179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014179.1 /DEF=Homo sapiens HSPC157 protein (HSPC157), mRNA. /FEA=mRNA /GEN=HSPC157 /PROD=HSPC157 protein /DB_XREF=gi:7661813 /UG=Hs.279842 HSPC157 protein /FL=gb:AF161506.1 gb:NM_014179.1 NM_014179 long intergenic non-protein coding RNA 339 LINC00339 29092 NR_023918 /// NR_023919 /// NR_109759 /// NR_109760 /// NR_109761 /// NR_109762 219866_at NM_016929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016929.1 /DEF=Homo sapiens chloride intracellular channel 5 (CLIC5), mRNA. /FEA=mRNA /GEN=CLIC5 /PROD=chloride intracellular channel 5 /DB_XREF=gi:8393146 /UG=Hs.283021 chloride intracellular channel 5 /FL=gb:AF216941.1 gb:NM_016929.1 NM_016929 chloride intracellular channel 5 CLIC5 53405 NM_001114086 /// NM_001256023 /// NM_016929 /// NR_045672 /// NR_045673 /// NR_045674 /// XM_006715114 /// XM_006715115 0002021 // response to dietary excess // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219867_at NM_024944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024944.1 /DEF=Homo sapiens hypothetical protein FLJ12627 (FLJ12627), mRNA. /FEA=mRNA /GEN=FLJ12627 /PROD=hypothetical protein FLJ12627 /DB_XREF=gi:13376424 /UG=Hs.283725 hypothetical protein FLJ12627 /FL=gb:NM_024944.1 NM_024944 chondrolectin CHODL 140578 NM_001204174 /// NM_001204175 /// NM_001204176 /// NM_001204177 /// NM_001204178 /// NM_024944 0007517 // muscle organ development // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005540 // hyaluronic acid binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation 219868_s_at NM_016376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016376.1 /DEF=Homo sapiens ANKHZN protein (ANKHZN), mRNA. /FEA=mRNA /GEN=ANKHZN /PROD=ANKHZN protein /DB_XREF=gi:7705277 /UG=Hs.284163 ANKHZN protein /FL=gb:AB037360.1 gb:NM_016376.1 NM_016376 ankyrin repeat and FYVE domain containing 1 ANKFY1 51479 NM_001257999 /// NM_016376 /// NM_020740 /// NR_047571 /// XM_005256679 /// XM_006721544 /// XR_429815 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219869_s_at NM_022154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022154.1 /DEF=Homo sapiens up-regulated by BCG-CWS (LOC64116), mRNA. /FEA=mRNA /GEN=LOC64116 /PROD=up-regulated by BCG-CWS /DB_XREF=gi:11545899 /UG=Hs.284205 up-regulated by BCG-CWS /FL=gb:NM_022154.1 NM_022154 solute carrier family 39 (zinc transporter), member 8 SLC39A8 64116 NM_001135146 /// NM_001135147 /// NM_001135148 /// NM_022154 /// XM_005263177 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from mutant phenotype /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from direct assay 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 219870_at NM_024997 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024997.1 /DEF=Homo sapiens hypothetical protein FLJ12668 (FLJ12668), mRNA. /FEA=mRNA /GEN=FLJ12668 /PROD=hypothetical protein FLJ12668 /DB_XREF=gi:13376506 /UG=Hs.287540 hypothetical protein FLJ12668 /FL=gb:NM_024997.1 NM_024997 activating transcription factor 7 interacting protein 2 ATF7IP2 80063 NM_001256160 /// NM_024997 /// NR_045815 /// NR_045816 /// XM_006720953 /// XM_006720954 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219871_at NM_024614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024614.1 /DEF=Homo sapiens hypothetical protein FLJ13197 (FLJ13197), mRNA. /FEA=mRNA /GEN=FLJ13197 /PROD=hypothetical protein FLJ13197 /DB_XREF=gi:13375829 /UG=Hs.29725 hypothetical protein FLJ13197 /FL=gb:NM_024614.1 NM_024614 KLF3 antisense RNA 1 KLF3-AS1 79667 NM_024614 /// NR_026804 219872_at NM_016613 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016613.1 /DEF=Homo sapiens AD021 protein (LOC51313), mRNA. /FEA=mRNA /GEN=LOC51313 /PROD=AD021 protein /DB_XREF=gi:7706151 /UG=Hs.323583 AD021 protein /FL=gb:AF223468.1 gb:NM_016613.1 NM_016613 family with sequence similarity 198, member B FAM198B 51313 NM_001031700 /// NM_001128424 /// NM_016613 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219873_at NM_024027 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024027.1 /DEF=Homo sapiens hypothetical protein MGC3279 similar to collectins (MGC3279), mRNA. /FEA=mRNA /GEN=MGC3279 /PROD=hypothetical protein MGC3279 similar tocollectins /DB_XREF=gi:13128971 /UG=Hs.32603 hypothetical protein MGC3279 similar to collectins /FL=gb:BC000078.1 gb:NM_024027.1 NM_024027 collectin sub-family member 11 COLEC11 78989 NM_001255982 /// NM_001255983 /// NM_001255984 /// NM_001255985 /// NM_001255986 /// NM_001255987 /// NM_001255988 /// NM_001255989 /// NM_024027 /// NM_199235 /// NR_045659 /// XM_005263853 /// XM_006711897 0007275 // multicellular organismal development // inferred from electronic annotation /// 0032502 // developmental process // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation 0005537 // mannose binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219874_at NM_024628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024628.1 /DEF=Homo sapiens hypothetical protein FLJ23188 (FLJ23188), mRNA. /FEA=mRNA /GEN=FLJ23188 /PROD=hypothetical protein FLJ23188 /DB_XREF=gi:13375853 /UG=Hs.36793 hypothetical protein FLJ23188 /FL=gb:NM_024628.1 NM_024628 solute carrier family 12, member 8 SLC12A8 84561 NM_001195483 /// NM_024628 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015293 // symporter activity // inferred from electronic annotation 219875_s_at NM_016076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016076.1 /DEF=Homo sapiens CGI-146 protein (LOC51029), mRNA. /FEA=mRNA /GEN=LOC51029 /PROD=CGI-146 protein /DB_XREF=gi:7705641 /UG=Hs.42409 CGI-146 protein /FL=gb:AF151904.1 gb:NM_016076.1 NM_016076 desumoylating isopeptidase 2 DESI2 51029 NM_016076 /// XM_005273154 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219876_s_at NM_017600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017600.1 /DEF=Homo sapiens hypothetical protein DKFZp434M0331 (DKFZp434M0331), mRNA. /FEA=mRNA /GEN=DKFZp434M0331 /PROD=hypothetical protein DKFZp434M0331 /DB_XREF=gi:13487903 /UG=Hs.48219 hypothetical protein DKFZp434M0331 /FL=gb:NM_017600.1 NM_017600 golgin A2 pseudogene 5 GOLGA2P5 55592 NM_017600 /// NR_024261 /// NR_036632 0015074 // DNA integration // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 219877_at NM_024645 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024645.1 /DEF=Homo sapiens hypothetical protein FLJ13842 (FLJ13842), mRNA. /FEA=mRNA /GEN=FLJ13842 /PROD=hypothetical protein FLJ13842 /DB_XREF=gi:13375886 /UG=Hs.50929 hypothetical protein FLJ13842 /FL=gb:NM_024645.1 NM_024645 zinc finger, matrin-type 4 ZMAT4 79698 NM_001135731 /// NM_024645 /// XM_005273644 /// XM_006716399 /// XM_006716400 /// XM_006716401 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219878_s_at NM_015995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015995.1 /DEF=Homo sapiens Kruppel-like factor 13 (KLF13), mRNA. /FEA=mRNA /GEN=KLF13 /PROD=Kruppel-like factor 13 /DB_XREF=gi:7706289 /UG=Hs.7104 Kruppel-like factor 13 /FL=gb:AF132599.1 gb:AF150628.1 gb:NM_015995.1 NM_015995 Kruppel-like factor 13 KLF13 51621 NM_015995 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 219879_s_at NM_024032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024032.1 /DEF=Homo sapiens hypothetical protein MGC3130 (MGC3130), mRNA. /FEA=mRNA /GEN=MGC3130 /PROD=hypothetical protein MGC3130 /DB_XREF=gi:13128981 /UG=Hs.72132 hypothetical protein MGC3130 /FL=gb:BC000121.1 gb:NM_024032.1 NM_024032 chromosome 17 open reading frame 53 C17orf53 78995 NM_001171251 /// NM_024032 /// XM_006722073 /// XM_006722074 /// XM_006722075 219880_at NM_022907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022907.1 /DEF=Homo sapiens hypothetical protein FLJ23053 (FLJ23053), mRNA. /FEA=mRNA /GEN=FLJ23053 /PROD=hypothetical protein FLJ23053 /DB_XREF=gi:12597650 /UG=Hs.94037 hypothetical protein FLJ23053 /FL=gb:NM_022907.1 NM_022907 uncharacterized LOC101928649 CTC-338M12.4 101928649 NR_109909 219881_s_at NM_022907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022907.1 /DEF=Homo sapiens hypothetical protein FLJ23053 (FLJ23053), mRNA. /FEA=mRNA /GEN=FLJ23053 /PROD=hypothetical protein FLJ23053 /DB_XREF=gi:12597650 /UG=Hs.94037 hypothetical protein FLJ23053 /FL=gb:NM_022907.1 NM_022907 uncharacterized LOC101928649 CTC-338M12.4 101928649 NR_109909 219882_at NM_024686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024686.1 /DEF=Homo sapiens hypothetical protein FLJ23033 (FLJ23033), mRNA. /FEA=mRNA /GEN=FLJ23033 /PROD=hypothetical protein FLJ23033 /DB_XREF=gi:13375957 /UG=Hs.96423 hypothetical protein FLJ23033 /FL=gb:NM_024686.1 NM_024686 tubulin tyrosine ligase-like family, member 7 TTLL7 79739 NM_024686 /// XM_005271208 /// XM_005271209 /// XM_005271210 /// XM_005271211 /// XM_006710903 /// XR_246294 0006464 // cellular protein modification process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0016874 // ligase activity // inferred from electronic annotation 219883_at NM_016611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016611.1 /DEF=Homo sapiens potassium inwardly-rectifying channel, subfamily K, member 4 (KCNK4), mRNA. /FEA=mRNA /GEN=KCNK4 /PROD=potassium inwardly-rectifying channel subfamilyK member 4 /DB_XREF=gi:7705561 /UG=Hs.97174 potassium inwardly-rectifying channel, subfamily K, member 4 /FL=gb:AF247042.1 gb:NM_016611.1 NM_016611 testis expressed 40 TEX40 25858 NM_001039496 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // traceable author statement 219884_at NM_014368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014368.1 /DEF=Homo sapiens LIM homeobox protein 6 (LHX6), mRNA. /FEA=mRNA /GEN=LHX6 /PROD=LIM homeobox protein 6 /DB_XREF=gi:7657304 /UG=Hs.103137 LIM homeobox protein 6 /FL=gb:AB031041.1 gb:AL136570.1 gb:NM_014368.1 NM_014368 LIM homeobox 6 LHX6 26468 NM_001242333 /// NM_001242334 /// NM_001242335 /// NM_014368 /// NM_199160 /// XM_005251915 /// XM_005251916 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from sequence or structural similarity /// 0021800 // cerebral cortex tangential migration // inferred from sequence or structural similarity /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from sequence or structural similarity /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219885_at NM_018042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018042.1 /DEF=Homo sapiens hypothetical protein FLJ10260 (FLJ10260), mRNA. /FEA=mRNA /GEN=FLJ10260 /PROD=hypothetical protein FLJ10260 /DB_XREF=gi:8922317 /UG=Hs.105859 hypothetical protein FLJ10260 /FL=gb:NM_018042.1 NM_018042 schlafen family member 12 SLFN12 55106 NM_001289009 /// NM_018042 /// XM_005257995 /// XM_006721967 0005524 // ATP binding // inferred from electronic annotation 219886_at NM_024548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024548.1 /DEF=Homo sapiens hypothetical protein FLJ23047 (FLJ23047), mRNA. /FEA=mRNA /GEN=FLJ23047 /PROD=hypothetical protein FLJ23047 /DB_XREF=gi:13375710 /UG=Hs.11340 hypothetical protein FLJ23047 /FL=gb:NM_024548.1 NM_024548 centrosomal protein 97kDa CEP97 79598 NM_024548 /// XM_005247759 /// XM_006713743 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 219887_at NM_018219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018219.1 /DEF=Homo sapiens hypothetical protein FLJ10786 (FLJ10786), mRNA. /FEA=mRNA /GEN=FLJ10786 /PROD=hypothetical protein FLJ10786 /DB_XREF=gi:8922668 /UG=Hs.121072 hypothetical protein FLJ10786 /FL=gb:NM_018219.1 NM_018219 coiled-coil domain containing 87 CCDC87 55231 NM_018219 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation 219888_at NM_003116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003116.1 /DEF=Homo sapiens sperm associated antigen 4 (SPAG4), mRNA. /FEA=mRNA /GEN=SPAG4 /PROD=sperm associated antigen 4 /DB_XREF=gi:11037054 /UG=Hs.123159 sperm associated antigen 4 /FL=gb:NM_003116.1 gb:AF262992.1 NM_003116 sperm associated antigen 4 SPAG4 6676 NM_003116 /// XM_005260519 /// XM_005260520 /// XM_005260521 /// XM_006723864 0007283 // spermatogenesis // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement 219889_at NM_005479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005479.1 /DEF=Homo sapiens frequently rearranged in advanced T-cell lymphomas (FRAT1), mRNA. /FEA=mRNA /GEN=FRAT1 /PROD=frequently rearranged in advanced T-celllymphomas /DB_XREF=gi:4885246 /UG=Hs.126057 frequently rearranged in advanced T-cell lymphomas /FL=gb:U58975.2 gb:NM_005479.1 NM_005479 frequently rearranged in advanced T-cell lymphomas 1 FRAT1 10023 NM_005479 /// NM_181355 0000578 // embryonic axis specification // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 219890_at NM_013252 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013252.1 /DEF=Homo sapiens C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 (CLECSF5), mRNA. /FEA=mRNA /GEN=CLECSF5 /PROD=C-type (calcium dependent,carbohydrate-recognition domain) lectin, superfamilymember 5 /DB_XREF=gi:10281668 /UG=Hs.126355 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 /FL=gb:NM_013252.1 gb:AF139768.1 NM_013252 C-type lectin domain family 5, member A CLEC5A 23601 NM_013252 /// XM_005249965 0002076 // osteoblast development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219891_at NM_017712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017712.1 /DEF=Homo sapiens hypothetical protein FLJ20208 (FLJ20208), mRNA. /FEA=mRNA /GEN=FLJ20208 /PROD=hypothetical protein FLJ20208 /DB_XREF=gi:8923197 /UG=Hs.131776 hypothetical protein FLJ20208 /FL=gb:NM_017712.1 NM_017712 pyroglutamyl-peptidase I PGPEP1 54858 NM_017712 /// XM_005259971 /// XM_006722783 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219892_at NM_023003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023003.1 /DEF=Homo sapiens transmembrane 6 superfamily member 1 (TM6SF1), mRNA. /FEA=mRNA /GEN=TM6SF1 /PROD=transmembrane 6 superfamily member 1 /DB_XREF=gi:13194198 /UG=Hs.133865 transmembrane 6 superfamily member 1 /FL=gb:AF255922.1 gb:NM_023003.1 NM_023003 transmembrane 6 superfamily member 1 TM6SF1 53346 NM_001144903 /// NM_023003 /// XM_005272432 /// XR_429457 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 219893_at NM_022903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022903.1 /DEF=Homo sapiens hypothetical protein FLJ12800 (FLJ12800), mRNA. /FEA=mRNA /GEN=FLJ12800 /PROD=hypothetical protein FLJ12800 /DB_XREF=gi:12597644 /UG=Hs.135214 hypothetical protein FLJ12800 /FL=gb:NM_022903.1 NM_022903 coiled-coil domain containing 71 CCDC71 64925 NM_022903 219894_at NM_019066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019066.1 /DEF=Homo sapiens MAGE-like 2 (MAGEL2), mRNA. /FEA=mRNA /GEN=MAGEL2 /PROD=MAGE-like 2 /DB_XREF=gi:9506924 /UG=Hs.141496 MAGE-like 2 /FL=gb:NM_019066.1 NM_019066 MAGE-like 2 MAGEL2 54551 NM_019066 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 219895_at NM_017938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017938.1 /DEF=Homo sapiens hypothetical protein FLJ20716 (FLJ20716), mRNA. /FEA=mRNA /GEN=FLJ20716 /PROD=hypothetical protein FLJ20716 /DB_XREF=gi:8923642 /UG=Hs.144517 hypothetical protein FLJ20716 /FL=gb:NM_017938.1 NM_017938 transmembrane protein 255A TMEM255A 55026 NM_001104544 /// NM_001104545 /// NM_017938 /// XR_430546 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219896_at NM_015722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015722.2 /DEF=Homo sapiens calcyon; D1 dopamine receptor-interacting protein (CALCYON), mRNA. /FEA=mRNA /GEN=CALCYON /PROD=calcyon /DB_XREF=gi:9257200 /UG=Hs.148680 calcyon; D1 dopamine receptor-interacting protein /FL=gb:AF225903.1 gb:NM_015722.2 NM_015722 calcyon neuron-specific vesicular protein CALY 50632 NM_015722 /// XM_005252685 0006897 // endocytosis // inferred from electronic annotation /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0032051 // clathrin light chain binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 219897_at NM_024787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024787.1 /DEF=Homo sapiens hypothetical protein FLJ12526 (FLJ12526), mRNA. /FEA=mRNA /GEN=FLJ12526 /PROD=hypothetical protein FLJ12526 /DB_XREF=gi:13376151 /UG=Hs.151237 hypothetical protein FLJ12526 /FL=gb:NM_024787.1 NM_024787 ring finger protein 122 RNF122 79845 NM_024787 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219898_at NM_018970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018970.2 /DEF=Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA. /FEA=mRNA /GEN=GPR85 /PROD=G protein-coupled receptor 85 /DB_XREF=gi:10190654 /UG=Hs.152009 G protein-coupled receptor 85 /FL=gb:AF250237.2 gb:NM_018970.2 gb:AB040800.1 NM_018970 G protein-coupled receptor 85 GPR85 54329 NM_001146265 /// NM_001146266 /// NM_001146267 /// NM_018970 /// XM_005250451 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement 219899_x_at NM_014434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014434.1 /DEF=Homo sapiens NADPH-dependent FMN and FAD containing oxidoreductase (NR1), mRNA. /FEA=mRNA /GEN=NR1 /PROD=NADPH-dependent FMN and FAD containingoxidoreductase /DB_XREF=gi:7657392 /UG=Hs.154899 NADPH-dependent FMN and FAD containing oxidoreductase /FL=gb:AF199509.1 gb:NM_014434.1 NM_014434 NADPH dependent diflavin oxidoreductase 1 NDOR1 27158 NM_001144026 /// NM_001144027 /// NM_001144028 /// NM_014434 /// XM_005266066 /// XM_006717056 /// XM_006717057 0008219 // cell death // inferred from direct assay /// 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation /// 0036245 // cellular response to menadione // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010181 // FMN binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // not recorded /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050661 // NADP binding // inferred from direct assay 219900_s_at NM_017908 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017908.1 /DEF=Homo sapiens hypothetical protein FLJ20626 (FLJ20626), mRNA. /FEA=mRNA /GEN=FLJ20626 /PROD=hypothetical protein FLJ20626 /DB_XREF=gi:8923581 /UG=Hs.164476 hypothetical protein FLJ20626 /FL=gb:NM_017908.1 NM_017908 zinc finger protein 446 ZNF446 55663 NM_017908 /// XM_005259052 /// XM_005259053 /// XM_006723266 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219901_at NM_018351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018351.1 /DEF=Homo sapiens hypothetical protein FLJ11183 (FLJ11183), mRNA. /FEA=mRNA /GEN=FLJ11183 /PROD=hypothetical protein FLJ11183 /DB_XREF=gi:8922920 /UG=Hs.170623 hypothetical protein FLJ11183 /FL=gb:NM_018351.1 NM_018351 FYVE, RhoGEF and PH domain containing 6 FGD6 55785 NM_018351 /// XM_005269024 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043088 // regulation of Cdc42 GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity /// 0046847 // filopodium assembly // inferred from sequence or structural similarity 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 219902_at NM_017614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017614.2 /DEF=Homo sapiens betaine-homocysteine methyltransferase 2 (BHMT2), mRNA. /FEA=mRNA /GEN=BHMT2 /PROD=betaine-homocysteine methyltransferase 2 /DB_XREF=gi:13162289 /UG=Hs.172382 betaine-homocysteine methyltransferase 2 /FL=gb:AF257473.1 gb:NM_017614.2 NM_017614 betaine--homocysteine S-methyltransferase 2 BHMT2 23743 NM_001178005 /// NM_017614 0006577 // amino-acid betaine metabolic process // inferred from direct assay /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0033477 // S-methylmethionine metabolic process // inferred from direct assay /// 0046500 // S-adenosylmethionine metabolic process // inferred from direct assay /// 0071267 // L-methionine salvage // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008898 // S-adenosylmethionine-homocysteine S-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047150 // betaine-homocysteine S-methyltransferase activity // inferred from direct assay /// 0061627 // S-methylmethionine-homocysteine S-methyltransferase activity // inferred from direct assay 219903_s_at NM_000770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000770.2 /DEF=Homo sapiens cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 (CYP2C8), transcript variant Hp1-1, mRNA. /FEA=mRNA /GEN=CYP2C8 /PROD=cytochrome P450, subfamily IIC, polypeptide 8,isoform 1 /DB_XREF=gi:13787188 /UG=Hs.174220 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 /FL=gb:NM_000770.2 gb:M17397.1 NM_000770 cytochrome P450, family 2, subfamily C, polypeptide 8 CYP2C8 1558 NM_000770 /// NM_001198853 /// NM_001198854 /// NM_001198855 /// NM_030878 0006082 // organic acid metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation 219904_at NM_024303 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024303.1 /DEF=Homo sapiens hypothetical protein MGC4161 (MGC4161), mRNA. /FEA=mRNA /GEN=MGC4161 /PROD=hypothetical protein MGC4161 /DB_XREF=gi:13236531 /UG=Hs.177688 hypothetical protein MGC4161 /FL=gb:BC002636.1 gb:NM_024303.1 NM_024303 zinc finger and SCAN domain containing 5A ZSCAN5A 79149 NM_024303 /// XM_005259254 /// XM_006723376 /// XM_006723377 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219905_at NM_018538 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018538.1 /DEF=Homo sapiens hypothetical protein PRO2801 (PRO2801), mRNA. /FEA=mRNA /GEN=PRO2801 /PROD=hypothetical protein PRO2801 /DB_XREF=gi:8924201 /UG=Hs.181223 hypothetical protein PRO2801 /FL=gb:AF119899.1 gb:NM_018538.1 NM_018538 erythroblast membrane-associated protein (Scianna blood group) ERMAP 114625 NM_001017922 /// NM_018538 /// XM_005270415 /// XM_006710313 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219906_at NM_018029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018029.1 /DEF=Homo sapiens hypothetical protein FLJ10213 (FLJ10213), mRNA. /FEA=mRNA /GEN=FLJ10213 /PROD=hypothetical protein FLJ10213 /DB_XREF=gi:8922290 /UG=Hs.189513 hypothetical protein FLJ10213 /FL=gb:NM_018029.1 NM_018029 endogenous Bornavirus-like nucleoprotein 2 EBLN2 55096 NM_018029 219907_at NM_006653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006653.1 /DEF=Homo sapiens suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) (SNT-2), mRNA. /FEA=mRNA /GEN=SNT-2 /PROD=suc1-associated neurotrophic factor target 2(FGFR signalling adaptor) /DB_XREF=gi:5730058 /UG=Hs.194208 suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) /FL=gb:AF036718.1 gb:NM_006653.1 NM_006653 fibroblast growth factor receptor substrate 3 FRS3 10817 NM_006653 /// XM_006714969 0007165 // signal transduction // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219908_at NM_014421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014421.1 /DEF=Homo sapiens dickkopf (Xenopus laevis) homolog 2 (DKK2), mRNA. /FEA=mRNA /GEN=DKK2 /PROD=dickkopf (Xenopus laevis) homolog 2 /DB_XREF=gi:7657022 /UG=Hs.211869 dickkopf (Xenopus laevis) homolog 2 /FL=gb:AF177395.1 gb:AB033208.1 gb:NM_014421.1 NM_014421 dickkopf WNT signaling pathway inhibitor 2 DKK2 27123 NM_014421 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 219909_at NM_024302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024302.1 /DEF=Homo sapiens matrix metalloproteinase 28 (MMP28), mRNA. /FEA=mRNA /GEN=MMP28 /PROD=matrix metalloproteinase 28 /DB_XREF=gi:13236529 /UG=Hs.231958 matrix metalloproteinase 28 /FL=gb:AF315683.1 gb:AF219624.1 gb:AF330002.1 gb:NM_024302.1 NM_024302 matrix metallopeptidase 28 MMP28 79148 NM_001032278 /// NM_024302 /// NM_032950 /// NR_111988 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219910_at NM_007076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007076.1 /DEF=Homo sapiens Huntingtin interacting protein E (HYPE), mRNA. /FEA=mRNA /GEN=HYPE /PROD=Huntingtin interacting protein E /DB_XREF=gi:13027623 /UG=Hs.234961 Huntingtin interacting protein E /FL=gb:BC001342.1 gb:NM_007076.1 NM_007076 FIC domain containing FICD 11153 NM_007076 0018117 // protein adenylylation // inferred from direct assay /// 0034259 // negative regulation of Rho GTPase activity // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0070733 // protein adenylyltransferase activity // inferred from direct assay 219911_s_at NM_016354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016354.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 12 (SLC21A12), mRNA. /FEA=mRNA /GEN=SLC21A12 /PROD=organic anion transporter OATP-E /DB_XREF=gi:7706516 /UG=Hs.235782 solute carrier family 21 (organic anion transporter), member 12 /FL=gb:AF205072.1 gb:AF187817.1 gb:AB031051.1 gb:NM_016354.1 NM_016354 solute carrier organic anion transporter family, member 4A1 SLCO4A1 28231 NM_016354 /// XM_005260203 /// XR_244115 /// XR_244116 /// XR_244117 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219912_s_at NM_005021 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005021.1 /DEF=Homo sapiens ectonucleotide pyrophosphatasephosphodiesterase 3 (ENPP3), mRNA. /FEA=mRNA /GEN=ENPP3 /PROD=ectonucleotide pyrophosphatasephosphodiesterase3 /DB_XREF=gi:4826895 /UG=Hs.264750 ectonucleotide pyrophosphatasephosphodiesterase 3 /FL=gb:AF005632.2 gb:NM_005021.1 NM_005021 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009143 // nucleoside triphosphate catabolic process // inferred from direct assay /// 0030505 // inorganic diphosphate transport // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // traceable author statement /// 0004551 // nucleotide diphosphatase activity // inferred from electronic annotation /// 0004551 // nucleotide diphosphatase activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0035529 // NADH pyrophosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047429 // nucleoside-triphosphate diphosphatase activity // inferred from direct assay 219913_s_at NM_016652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016652.2 /DEF=Homo sapiens CGI-201 protein (LOC51340), mRNA. /FEA=mRNA /GEN=LOC51340 /PROD=CGI-201 protein /DB_XREF=gi:11072090 /UG=Hs.268281 crooked neck protein (crn) /FL=gb:AF255443.2 gb:NM_016652.2 gb:AF318302.1 NM_016652 crooked neck pre-mRNA splicing factor 1 CRNKL1 51340 NM_001278625 /// NM_001278626 /// NM_001278627 /// NM_001278628 /// NM_016652 0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 219914_at NM_004826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004826.1 /DEF=Homo sapiens endothelin converting enzyme-like 1 (ECEL1), mRNA. /FEA=mRNA /GEN=ECEL1 /PROD=endothelin converting enzyme-like 1 /DB_XREF=gi:4758231 /UG=Hs.26880 endothelin converting enzyme-like 1 /FL=gb:NM_004826.1 NM_004826 endothelin converting enzyme-like 1 ECEL1 9427 NM_001290787 /// NM_004826 0003016 // respiratory system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219915_s_at NM_018593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018593.1 /DEF=Homo sapiens hypothetical protein PRO0813 (PRO0813), mRNA. /FEA=mRNA /GEN=PRO0813 /PROD=hypothetical protein PRO0813 /DB_XREF=gi:8923980 /UG=Hs.270087 hypothetical protein PRO0813 /FL=gb:AF116652.1 gb:NM_018593.1 NM_018593 solute carrier family 16 (aromatic amino acid transporter), member 10 SLC16A10 117247 NM_018593 /// XM_005266818 /// XM_005266819 /// XM_006715329 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0015801 // aromatic amino acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // traceable author statement 219916_s_at NM_025236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025236.1 /DEF=Homo sapiens HZFw1 protein (HZFW1), mRNA. /FEA=mRNA /GEN=HZFW1 /PROD=HZFw1 protein /DB_XREF=gi:13376843 /UG=Hs.270549 HZFw1 protein /FL=gb:AF238315.1 gb:NM_025236.1 NM_025236 ring finger protein 39 RNF39 80352 NM_025236 /// NM_170769 /// NM_170770 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219917_at NM_024936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024936.1 /DEF=Homo sapiens hypothetical protein FLJ23024 (FLJ23024), mRNA. /FEA=mRNA /GEN=FLJ23024 /PROD=hypothetical protein FLJ23024 /DB_XREF=gi:13376409 /UG=Hs.278945 hypothetical protein FLJ23024 /FL=gb:NM_024936.1 NM_024936 zinc finger, CCHC domain containing 4 ZCCHC4 29063 NM_024936 /// XM_005248155 /// XM_005248156 /// XM_005248157 0032259 // methylation // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219918_s_at NM_018123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018123.1 /DEF=Homo sapiens hypothetical protein FLJ10517 (FLJ10517), mRNA. /FEA=mRNA /GEN=FLJ10517 /PROD=hypothetical protein FLJ10517 /DB_XREF=gi:8922484 /UG=Hs.279797 hypothetical protein FLJ10517 /FL=gb:NM_018123.1 NM_018123 asp (abnormal spindle) homolog, microcephaly associated (Drosophila) ASPM 259266 NM_001206846 /// NM_018136 0001764 // neuron migration // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0021873 // forebrain neuroblast division // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045769 // negative regulation of asymmetric cell division // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051661 // maintenance of centrosome location // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 219919_s_at NM_018276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018276.1 /DEF=Homo sapiens hypothetical protein FLJ10928 (FLJ10928), mRNA. /FEA=mRNA /GEN=FLJ10928 /PROD=hypothetical protein FLJ10928 /DB_XREF=gi:8922776 /UG=Hs.279808 hypothetical protein FLJ10928 /FL=gb:NM_018276.1 NM_018276 slingshot protein phosphatase 3 SSH3 54961 NM_017857 /// NM_018276 /// XM_005274070 /// XM_005274071 /// XM_005274072 /// XM_006718592 /// XR_247205 /// XR_247206 0006470 // protein dephosphorylation // not recorded /// 0008064 // regulation of actin polymerization or depolymerization // not recorded /// 0010591 // regulation of lamellipodium assembly // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 219920_s_at NM_021971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021971.1 /DEF=Homo sapiens GDP-mannose pyrophosphorylase B (GMPPB), transcript variant 2, mRNA. /FEA=mRNA /GEN=GMPPB /PROD=GDP-mannose pyrophosphorylase B, isoform 2 /DB_XREF=gi:11761620 /UG=Hs.28077 GDP-mannose pyrophosphorylase B /FL=gb:NM_021971.1 gb:BC001141.1 gb:AF135421.1 NM_021971 adhesion molecule with Ig-like domain 3 /// GDP-mannose pyrophosphorylase B AMIGO3 /// GMPPB 29925 /// 386724 NM_013334 /// NM_021971 /// NM_198722 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004475 // mannose-1-phosphate guanylyltransferase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 219921_s_at NM_024940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024940.1 /DEF=Homo sapiens hypothetical protein FLJ21034 (FLJ21034), mRNA. /FEA=mRNA /GEN=FLJ21034 /PROD=hypothetical protein FLJ21034 /DB_XREF=gi:13376416 /UG=Hs.282466 hypothetical protein FLJ21034 /FL=gb:NM_024940.1 NM_024940 dedicator of cytokinesis 5 DOCK5 80005 NM_024940 /// XM_005273650 /// XM_005273651 /// XM_006716402 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219922_s_at NM_021070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021070.1 /DEF=Homo sapiens latent transforming growth factor beta binding protein 3 (LTBP3), mRNA. /FEA=mRNA /GEN=LTBP3 /PROD=latent transforming growth factor beta bindingprotein 3 /DB_XREF=gi:10835104 /UG=Hs.289019 latent transforming growth factor beta binding protein 3 /FL=gb:NM_021070.1 gb:AF135960.2 NM_021070 latent transforming growth factor beta binding protein 3 LTBP3 4054 NM_001130144 /// NM_001164266 /// NM_021070 0001501 // skeletal system development // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0036363 // transforming growth factor beta activation // inferred from mutant phenotype /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0046849 // bone remodeling // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 1902462 // positive regulation of mesenchymal stem cell proliferation // inferred from mutant phenotype /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 219923_at NM_025188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025188.1 /DEF=Homo sapiens hypothetical protein FLJ13181 (FLJ13181), mRNA. /FEA=mRNA /GEN=FLJ13181 /PROD=hypothetical protein FLJ13181 /DB_XREF=gi:13376779 /UG=Hs.301526 hypothetical protein FLJ13181 /FL=gb:NM_025188.1 NM_025188 tripartite motif containing 45 TRIM45 80263 NM_001145635 /// NM_025188 /// XR_246297 0060348 // bone development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219924_s_at NM_007167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007167.1 /DEF=Homo sapiens zinc finger protein 258 (ZNF258), mRNA. /FEA=mRNA /GEN=ZNF258 /PROD=zinc finger protein 258 /DB_XREF=gi:6005977 /UG=Hs.301637 zinc finger protein 258 /FL=gb:AF055470.1 gb:NM_007167.1 NM_007167 zinc finger, MYM-type 6 ZMYM6 9204 NM_007167 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219925_at NM_007167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007167.1 /DEF=Homo sapiens zinc finger protein 258 (ZNF258), mRNA. /FEA=mRNA /GEN=ZNF258 /PROD=zinc finger protein 258 /DB_XREF=gi:6005977 /UG=Hs.301637 zinc finger protein 258 /FL=gb:AF055470.1 gb:NM_007167.1 NM_007167 zinc finger, MYM-type 6 ZMYM6 9204 NM_007167 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219926_at NM_022361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022361.1 /DEF=Homo sapiens popeye protein 3 (POP3), mRNA. /FEA=mRNA /GEN=POP3 /PROD=popeye protein 3 /DB_XREF=gi:11641280 /UG=Hs.303154 popeye protein 3 /FL=gb:AF204171.1 gb:NM_022361.1 NM_022361 popeye domain containing 3 POPDC3 64208 NM_022361 /// NR_024539 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 219927_at NM_015962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015962.1 /DEF=Homo sapiens CGI-35 protein (LOC51077), mRNA. /FEA=mRNA /GEN=LOC51077 /PROD=CGI-35 protein /DB_XREF=gi:7705729 /UG=Hs.306198 CGI-35 protein /FL=gb:AF132969.1 gb:NM_015962.1 NM_015962 FCF1 rRNA-processing protein FCF1 51077 NM_015962 /// XM_005267730 /// XM_005267731 /// XR_245689 /// XR_245690 /// XR_245691 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 219928_s_at NM_012189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012189.1 /DEF=Homo sapiens fibrousheathin II (FSP-2), mRNA. /FEA=mRNA /GEN=FSP-2 /PROD=fibrousheathin II /DB_XREF=gi:6912377 /UG=Hs.314452 fibrousheathin II /FL=gb:AF088868.1 gb:NM_012189.1 NM_012189 calcium binding tyrosine-(Y)-phosphorylation regulated CABYR 26256 NM_012189 /// NM_138643 /// NM_138644 /// NM_153768 /// NM_153769 /// NM_153770 /// XM_005258245 /// XM_005258246 /// XM_005258247 0001539 // cilium or flagellum-dependent cell motility // inferred from direct assay /// 0003351 // epithelial cilium movement // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0048240 // sperm capacitation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0035686 // sperm fibrous sheath // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 219929_s_at NM_024071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024071.1 /DEF=Homo sapiens hypothetical protein MGC2550 (MGC2550), mRNA. /FEA=mRNA /GEN=MGC2550 /PROD=hypothetical protein MGC2550 /DB_XREF=gi:13129053 /UG=Hs.318498 hypothetical protein MGC2550 /FL=gb:BC001130.1 gb:NM_024071.1 NM_024071 zinc finger, FYVE domain containing 21 ZFYVE21 79038 NM_001198953 /// NM_024071 0005768 // endosome // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 219930_at NM_007250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007250.1 /DEF=Homo sapiens Kruppel-like factor 8 (KLF8), mRNA. /FEA=mRNA /GEN=KLF8 /PROD=Kruppel-like factor 8 /DB_XREF=gi:6005979 /UG=Hs.320861 Kruppel-like factor 8 /FL=gb:U28282.1 gb:NM_007250.1 NM_007250 Kruppel-like factor 8 KLF8 11279 NM_001159296 /// NM_007250 /// XM_005261977 /// XM_005261978 /// XM_005261979 /// XM_006724575 /// XM_006724576 /// XR_244466 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219931_s_at NM_021633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021633.1 /DEF=Homo sapiens kelch-like protein C3IP1 (C3IP1), mRNA. /FEA=mRNA /GEN=C3IP1 /PROD=kelch-like protein C3IP1 /DB_XREF=gi:11056005 /UG=Hs.3826 kelch-like protein C3IP1 /FL=gb:AF190900.1 gb:NM_021633.1 gb:BC003183.1 gb:BC004175.1 NM_021633 kelch-like family member 12 KLHL12 59349 NM_021633 /// XM_005245403 /// XM_006711478 /// XM_006711479 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0048208 // COPII vesicle coating // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from mutant phenotype /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 219932_at NM_014031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014031.1 /DEF=Homo sapiens VLCS-H1 protein (VLCS-H1), mRNA. /FEA=mRNA /GEN=VLCS-H1 /PROD=very long-chain acyl-CoA synthetase homolog 1 /DB_XREF=gi:13325054 /UG=Hs.49765 VLCS-H1 protein /FL=gb:NM_014031.1 gb:AF064254.1 NM_014031 solute carrier family 27 (fatty acid transporter), member 6 SLC27A6 28965 NM_001017372 /// NM_014031 /// XM_005271967 /// XM_005271968 /// XM_005271969 /// XM_005271970 /// XM_005271971 0000038 // very long-chain fatty acid metabolic process // traceable author statement /// 0001676 // long-chain fatty acid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from electronic annotation 219933_at NM_016066 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016066.1 /DEF=Homo sapiens CGI-133 protein (LOC51022), mRNA. /FEA=mRNA /GEN=LOC51022 /PROD=CGI-133 protein /DB_XREF=gi:7705627 /UG=Hs.5054 CGI-133 protein /FL=gb:AF151891.1 gb:NM_016066.1 gb:AF132495.2 NM_016066 glutaredoxin 2 GLRX2 51022 NM_001243399 /// NM_016066 /// NM_197962 /// XM_005245231 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006749 // glutathione metabolic process // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0009266 // response to temperature stimulus // non-traceable author statement /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0030154 // cell differentiation // non-traceable author statement /// 0042262 // DNA protection // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0045454 // cell redox homeostasis // traceable author statement /// 0051775 // response to redox state // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003756 // protein disulfide isomerase activity // traceable author statement /// 0008794 // arsenate reductase (glutaredoxin) activity // traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015038 // glutathione disulfide oxidoreductase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 219934_s_at NM_005420 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005420.1 /DEF=Homo sapiens sulfotransferase, estrogen-preferring (STE), mRNA. /FEA=mRNA /GEN=STE /PROD=sulfotransferase, estrogen-preferring /DB_XREF=gi:4885616 /UG=Hs.54576 sulfotransferase, estrogen-preferring /FL=gb:U08098.1 gb:NM_005420.1 NM_005420 sulfotransferase family 1E, estrogen-preferring, member 1 SULT1E1 6783 NM_005420 0006805 // xenobiotic metabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay 0004304 // estrone sulfotransferase activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay /// 0050294 // steroid sulfotransferase activity // inferred from direct assay /// 0050294 // steroid sulfotransferase activity // traceable author statement 219935_at NM_007038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007038.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5), mRNA. /FEA=mRNA /GEN=ADAMTS5 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-5 preproprotein /DB_XREF=gi:5901887 /UG=Hs.58324 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) /FL=gb:AF142099.1 gb:NM_007038.1 NM_007038 ADAM metallopeptidase with thrombospondin type 1 motif, 5 ADAMTS5 11096 NM_007038 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219936_s_at NM_023915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023915.1 /DEF=Homo sapiens G protein-coupled receptor 87 (GPR87), mRNA. /FEA=mRNA /GEN=GPR87 /PROD=G protein-coupled receptor 87 /DB_XREF=gi:13236505 /UG=Hs.58561 G protein-coupled receptor 87 /FL=gb:AF237763.1 gb:NM_023915.1 NM_023915 G protein-coupled receptor 87 GPR87 53836 NM_023915 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation 219937_at NM_013381 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013381.1 /DEF=Homo sapiens thyrotropin-releasing hormone degrading ectoenzyme (TRHDE), mRNA. /FEA=mRNA /GEN=TRHDE /PROD=thyrotropin-releasing hormone degradingectoenzyme /DB_XREF=gi:7019560 /UG=Hs.6510 thyrotropin-releasing hormone degrading ectoenzyme /FL=gb:AF126372.1 gb:NM_013381.1 NM_013381 thyrotropin-releasing hormone degrading enzyme TRHDE 29953 NM_013381 /// XM_005268819 0006508 // proteolysis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219938_s_at NM_024430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024430.1 /DEF=Homo sapiens proline-serine-threonine phosphatase interacting protein 2 (PSTPIP2), mRNA. /FEA=mRNA /GEN=PSTPIP2 /PROD=proline-serine-threonine phosphatase interactingprotein 2 /DB_XREF=gi:13270468 /UG=Hs.69149 proline-serine-threonine phosphatase interacting protein 2 /FL=gb:NM_024430.1 NM_024430 proline-serine-threonine phosphatase interacting protein 2 PSTPIP2 9050 NM_024430 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219939_s_at NM_007158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007158.1 /DEF=Homo sapiens NRAS-related gene (D1S155E), mRNA. /FEA=mRNA /GEN=D1S155E /PROD=NRAS-related gene /DB_XREF=gi:6005738 /UG=Hs.69855 NRAS-related gene /FL=gb:AF077054.1 gb:NM_007158.1 NM_007158 cold shock domain containing E1, RNA-binding CSDE1 7812 NM_001007553 /// NM_001130523 /// NM_001242891 /// NM_001242892 /// NM_001242893 /// NM_007158 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008584 // male gonad development // traceable author statement /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219940_s_at NM_018386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018386.1 /DEF=Homo sapiens hypothetical protein FLJ11305 (FLJ11305), mRNA. /FEA=mRNA /GEN=FLJ11305 /PROD=hypothetical protein FLJ11305 /DB_XREF=gi:8922986 /UG=Hs.7049 hypothetical protein FLJ11305 /FL=gb:NM_018386.1 NM_018386 PCI domain containing 2 PCID2 55795 NM_001127202 /// NM_001127203 /// NM_001258212 /// NM_001258213 /// NM_018386 /// XM_005268324 /// XM_005268325 /// XM_006719976 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from mutant phenotype /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype 0005515 // protein binding // inferred from electronic annotation 219941_at NM_018279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018279.1 /DEF=Homo sapiens hypothetical protein FLJ10936 (FLJ10936), mRNA. /FEA=mRNA /GEN=FLJ10936 /PROD=hypothetical protein FLJ10936 /DB_XREF=gi:8922782 /UG=Hs.7337 hypothetical protein FLJ10936 /FL=gb:NM_018279.1 NM_018279 transmembrane protein 19 TMEM19 55266 NM_018279 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219942_at NM_021223 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021223.1 /DEF=Homo sapiens myosin light chain 2a (LOC58498), mRNA. /FEA=mRNA /GEN=LOC58498 /PROD=myosin light chain 2a /DB_XREF=gi:10864036 /UG=Hs.75636 myosin light chain 2a /FL=gb:NM_021223.1 NM_021223 myosin, light chain 7, regulatory MYL7 58498 NM_021223 /// XM_005249816 /// XM_005249817 0006939 // smooth muscle contraction // non-traceable author statement /// 0030048 // actin filament-based movement // non-traceable author statement 0016459 // myosin complex // non-traceable author statement /// 0031672 // A band // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation 0000146 // microfilament motor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 219943_s_at NM_022741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022741.1 /DEF=Homo sapiens hypothetical protein FLJ11850 (FLJ11850), mRNA. /FEA=mRNA /GEN=FLJ11850 /PROD=hypothetical protein FLJ11850 /DB_XREF=gi:12232398 /UG=Hs.7966 hypothetical protein FLJ11850 /FL=gb:NM_022741.1 NM_022741 ubiquitin specific peptidase 46 USP46 64854 NM_001134223 /// NM_001286767 /// NM_001286768 /// NM_022832 0001662 // behavioral fear response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 219944_at NM_024692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024692.1 /DEF=Homo sapiens hypothetical protein FLJ21069 (FLJ21069), mRNA. /FEA=mRNA /GEN=FLJ21069 /PROD=hypothetical protein FLJ21069 /DB_XREF=gi:13375970 /UG=Hs.98640 hypothetical protein FLJ21069 /FL=gb:NM_024692.1 NM_024692 CAP-GLY domain containing linker protein family, member 4 CLIP4 79745 NM_001287527 /// NM_001287528 /// NM_024692 /// NR_109844 /// XM_005264562 /// XM_005264563 /// XM_005264564 /// XM_006712104 /// XM_006712105 0005515 // protein binding // inferred from electronic annotation 219945_at NM_013264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013264.1 /DEF=Homo sapiens gonadotropin-regulated testicular RNA helicase (GRTH), mRNA. /FEA=mRNA /GEN=GRTH /PROD=gonadotropin-regulated testicular RNA helicase /DB_XREF=gi:7019398 /UG=Hs.98738 gonadotropin-regulated testicular RNA helicase /FL=gb:AF155140.1 gb:NM_013264.1 NM_013264 DEAD (Asp-Glu-Ala-Asp) box helicase 25 DDX25 29118 NM_013264 /// XM_005271529 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006406 // mRNA export from nucleus // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0033391 // chromatoid body // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from sequence or structural similarity /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219946_x_at NM_024729 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024729.1 /DEF=Homo sapiens hypothetical protein FLJ13881 (FLJ13881), mRNA. /FEA=mRNA /GEN=FLJ13881 /PROD=hypothetical protein FLJ13881 /DB_XREF=gi:13376043 /UG=Hs.115412 hypothetical protein FLJ13881 /FL=gb:NM_024729.1 NM_024729 myosin, heavy chain 14, non-muscle MYH14 79784 NM_001077186 /// NM_001145809 /// NM_024729 /// XM_006723386 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from mutant phenotype /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097513 // myosin II filament // inferred from direct assay 0000146 // microfilament motor activity // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 219947_at NM_016184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016184.1 /DEF=Homo sapiens C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 (CLECSF6), mRNA. /FEA=mRNA /GEN=CLECSF6 /PROD=C-type (calcium dependent,carbohydrate-recognition domain) lectin, superfamilymember 6 /DB_XREF=gi:7705337 /UG=Hs.115515 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 /FL=gb:AF109146.1 gb:NM_016184.1 gb:AF067800.1 NM_016184 C-type lectin domain family 4, member A CLEC4A 50856 NM_016184 /// NM_194447 /// NM_194448 /// NM_194450 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 219948_x_at NM_024743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024743.1 /DEF=Homo sapiens hypothetical protein FLJ21934 (FLJ21934), mRNA. /FEA=mRNA /GEN=FLJ21934 /PROD=hypothetical protein FLJ21934 /DB_XREF=gi:13376065 /UG=Hs.122583 hypothetical protein FLJ21934 /FL=gb:NM_024743.1 NM_024743 UDP glucuronosyltransferase 2 family, polypeptide A3 UGT2A3 79799 NM_024743 /// NR_024010 /// XM_006714305 /// XM_006725000 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0052695 // cellular glucuronidation // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 219949_at NM_024512 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024512.1 /DEF=Homo sapiens leucine-rich repeat-containing 2 (LRRC2), mRNA. /FEA=mRNA /GEN=LRRC2 /PROD=leucine-rich repeat-containing 2 /DB_XREF=gi:13378142 /UG=Hs.125790 leucine-rich repeat-containing 2 /FL=gb:NM_024512.1 NM_024512 leucine rich repeat containing 2 LRRC2 79442 NM_024512 /// NM_024750 /// XM_006713332 0005515 // protein binding // inferred from electronic annotation 219950_s_at NM_012454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012454.1 /DEF=Homo sapiens T-cell lymphoma invasion and metastasis 2 (TIAM2), mRNA. /FEA=mRNA /GEN=TIAM2 /PROD=T-cell lymphoma invasion and metastasis 2 /DB_XREF=gi:6912703 /UG=Hs.12598 T-cell lymphoma invasion and metastasis 2 /FL=gb:AF120323.1 gb:NM_012454.1 NM_012454 T-cell lymphoma invasion and metastasis 2 TIAM2 26230 NM_001010927 /// NM_012454 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation 219951_s_at NM_018152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018152.1 /DEF=Homo sapiens hypothetical protein FLJ10600 (FLJ10600), mRNA. /FEA=mRNA /GEN=FLJ10600 /PROD=hypothetical protein FLJ10600 /DB_XREF=gi:8922543 /UG=Hs.128766 hypothetical protein FLJ10600 /FL=gb:NM_018152.1 NM_018152 double zinc ribbon and ankyrin repeat domains 1 DZANK1 55184 NM_001099407 /// NM_018152 /// XM_005260742 /// XM_005260743 /// XM_006723581 /// XM_006723582 /// XM_006723583 /// XM_006723584 /// XM_006723585 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219952_s_at NM_020533 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020533.1 /DEF=Homo sapiens mucolipin 1 (MCOLN1), mRNA. /FEA=mRNA /GEN=MCOLN1 /PROD=mucolipin 1 /DB_XREF=gi:10092596 /UG=Hs.12909 mucolipin 1 /FL=gb:NM_020533.1 gb:BC005149.1 gb:AF287269.1 gb:AF249319.1 NM_020533 mucolipin 1 MCOLN1 57192 NM_020533 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005261 // cation channel activity // non-traceable author statement /// 0072345 // NAADP-sensitive calcium-release channel activity // inferred from electronic annotation 219953_s_at NM_020642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020642.1 /DEF=Homo sapiens chromosome 11 open reading frame 17 (C11ORF17), mRNA. /FEA=mRNA /GEN=C11ORF17 /PROD=chromosome 11 open reading frame 17 /DB_XREF=gi:11034852 /UG=Hs.131180 chromosome 11 open reading frame 17 /FL=gb:NM_020642.1 NM_020642 A kinase (PRKA) interacting protein 1 AKIP1 56672 NM_001206645 /// NM_001206646 /// NM_001206647 /// NM_001206648 /// NM_020642 /// NM_182901 /// NR_045417 /// NR_045418 /// XM_006718264 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219954_s_at NM_020973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020973.1 /DEF=Homo sapiens cytosolic beta-glucosidase (GLUC), mRNA. /FEA=mRNA /GEN=GLUC /PROD=cytosolic beta-glucosidase /DB_XREF=gi:13273312 /UG=Hs.146182 cytosolic beta-glucosidase /FL=gb:AB017913.1 gb:AF317840.1 gb:NM_020973.1 NM_020973 glucosidase, beta, acid 3 GBA3 57733 NM_001128432 /// NM_001277225 /// NM_020973 /// NR_102355 /// NR_102356 /// NR_102357 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016139 // glycoside catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046477 // glycosylceramide catabolic process // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // inferred from direct assay /// 0008422 // beta-glucosidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0017042 // glycosylceramidase activity // inferred from direct assay 219955_at NM_019079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019079.1 /DEF=Homo sapiens hypothetical protein (FLJ10884), mRNA. /FEA=mRNA /GEN=FLJ10884 /PROD=hypothetical protein /DB_XREF=gi:9506624 /UG=Hs.150890 hypothetical protein /FL=gb:NM_019079.1 NM_019079 LINE-1 type transposase domain containing 1 L1TD1 54596 NM_001164835 /// NM_019079 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation 219956_at NM_007210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007210.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6), mRNA. /FEA=mRNA /GEN=GALNT6 /PROD=polypeptide N-acetylgalactosaminyltransferase 6 /DB_XREF=gi:13124893 /UG=Hs.151678 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) /FL=gb:NM_007210.2 NM_007210 polypeptide N-acetylgalactosaminyltransferase 6 GALNT6 11226 NM_007210 /// XM_005268607 /// XM_005268608 /// XM_006719214 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219957_at NM_017987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017987.1 /DEF=Homo sapiens hypothetical protein FLJ10063 (FLJ10063), mRNA. /FEA=mRNA /GEN=FLJ10063 /PROD=hypothetical protein FLJ10063 /DB_XREF=gi:8922215 /UG=Hs.154091 hypothetical protein FLJ10063 /FL=gb:NM_017987.1 NM_017987 RUN and FYVE domain containing 2 RUFY2 55680 NM_001042417 /// NM_001278225 /// NM_017987 /// NR_103475 /// NR_103476 /// XM_005269952 /// XM_005269953 /// XM_005269955 /// XM_005269956 /// XM_005269957 /// XM_005269959 /// XM_005269960 /// XM_006717911 /// XM_006717912 /// XR_246097 0005634 // nucleus // inferred from electronic annotation 0046872 // metal ion binding // inferred from electronic annotation 219958_at NM_018354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018354.1 /DEF=Homo sapiens hypothetical protein FLJ11190 (FLJ11190), mRNA. /FEA=mRNA /GEN=FLJ11190 /PROD=hypothetical protein FLJ11190 /DB_XREF=gi:8922926 /UG=Hs.155071 hypothetical protein FLJ11190 /FL=gb:NM_018354.1 NM_018354 transmembrane protein 74B TMEM74B 55321 NM_018354 /// XM_005260747 /// XM_005260748 /// XM_006723586 /// XM_006723587 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219959_at NM_017947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017947.1 /DEF=Homo sapiens hypothetical protein FLJ20733 (FLJ20733), mRNA. /FEA=mRNA /GEN=FLJ20733 /PROD=hypothetical protein FLJ20733 /DB_XREF=gi:8923660 /UG=Hs.157986 hypothetical protein FLJ20733 /FL=gb:NM_017947.1 NM_017947 molybdenum cofactor sulfurase MOCOS 55034 NM_017947 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0043545 // molybdopterin cofactor metabolic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0008265 // Mo-molybdopterin cofactor sulfurase activity // inferred from mutant phenotype /// 0008265 // Mo-molybdopterin cofactor sulfurase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 219960_s_at NM_015984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015984.1 /DEF=Homo sapiens ubiquitin C-terminal hydrolase UCH37 (UCH37), mRNA. /FEA=mRNA /GEN=UCH37 /PROD=ubiquitin C-terminal hydrolase UCH37 /DB_XREF=gi:7706752 /UG=Hs.171581 ubiquitin C-terminal hydrolase UCH37 /FL=gb:AF147717.1 gb:NM_015984.1 NM_015984 ubiquitin carboxyl-terminal hydrolase L5 UCHL5 51377 NM_001199261 /// NM_001199262 /// NM_001199263 /// NM_015984 /// NR_037607 /// XM_005245244 /// XM_005245245 /// XM_005245246 /// XM_005245247 /// XM_005245248 /// XM_005245249 /// XM_006711366 /// XM_006711367 /// XM_006711368 /// XM_006711369 /// XM_006711370 /// XM_006711371 /// XM_006711372 /// XM_006711373 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from direct assay 219961_s_at NM_018474 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018474.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT013 (HT013), mRNA. /FEA=mRNA /GEN=HT013 /PROD=uncharacterized hypothalamus protein HT013 /DB_XREF=gi:8923814 /UG=Hs.173515 uncharacterized hypothalamus protein HT013 /FL=gb:AF220187.1 gb:NM_018474.1 NM_018474 kizuna centrosomal protein KIZ 55857 NM_001163022 /// NM_001163023 /// NM_001276389 /// NM_018474 0007051 // spindle organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 219962_at NM_021804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021804.1 /DEF=Homo sapiens angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), mRNA. /FEA=mRNA /GEN=ACE2 /PROD=angiotensin I converting enzyme(peptidyl-dipeptidase A) 2 /DB_XREF=gi:11225608 /UG=Hs.178098 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 /FL=gb:NM_021804.1 gb:AB046569.1 gb:AF241254.1 gb:AF291820.1 NM_021804 angiotensin I converting enzyme 2 ACE2 59272 NM_021804 0001817 // regulation of cytokine production // inferred by curator /// 0002003 // angiotensin maturation // traceable author statement /// 0002005 // angiotensin catabolic process in blood // inferred by curator /// 0003051 // angiotensin-mediated drinking behavior // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0032800 // receptor biosynthetic process // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042312 // regulation of vasodilation // inferred by curator /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046718 // viral entry into host cell // traceable author statement /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred by curator /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred by curator 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0001618 // virus receptor activity // inferred from mutant phenotype /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004180 // carboxypeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008241 // peptidyl-dipeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219963_at NM_016364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016364.1 /DEF=Homo sapiens protein phosphatase (LOC51207), mRNA. /FEA=mRNA /GEN=LOC51207 /PROD=protein phosphatase /DB_XREF=gi:7705958 /UG=Hs.178170 protein phosphatase /FL=gb:AB027004.1 gb:NM_016364.1 NM_016364 dual specificity phosphatase 13 DUSP13 51207 NM_001007271 /// NM_001007272 /// NM_001007273 /// NM_001007274 /// NM_001007275 /// NM_016364 /// XM_005269883 /// XM_005269884 /// XM_005269886 /// XM_005269887 /// XM_005269888 /// XM_005269889 /// XM_005269890 0006470 // protein dephosphorylation // not recorded /// 0007126 // meiotic nuclear division // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 219964_at NM_017744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017744.1 /DEF=Homo sapiens hypothetical protein FLJ20284 (FLJ20284), mRNA. /FEA=mRNA /GEN=FLJ20284 /PROD=hypothetical protein FLJ20284 /DB_XREF=gi:8923264 /UG=Hs.191228 hypothetical protein FLJ20284 /FL=gb:NM_017744.1 NM_017744 suppression of tumorigenicity 7 like ST7L 54879 NM_017744 /// NM_138727 /// NM_138728 /// NM_138729 /// NM_198327 /// NM_198328 /// XM_005270963 /// XM_005270964 /// XM_005270966 /// XM_005270970 /// XM_006710708 /// XM_006710709 /// XR_246280 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0021871 // forebrain regionalization // inferred from electronic annotation /// 0021871 // forebrain regionalization // inferred from expression pattern /// 0030182 // neuron differentiation // /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060492 // lung induction // inferred from electronic annotation /// 0060638 // mesenchymal-epithelial cell signaling // inferred from electronic annotation /// 0061072 // iris morphogenesis // inferred from sequence or structural similarity /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // 219965_s_at NM_024859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024859.1 /DEF=Homo sapiens hypothetical protein FLJ21687 (FLJ21687), mRNA. /FEA=mRNA /GEN=FLJ21687 /PROD=hypothetical protein FLJ21687 /DB_XREF=gi:13376285 /UG=Hs.193170 hypothetical protein FLJ21687 /FL=gb:NM_024859.1 NM_024859 MAGI family member, X-linked MAGIX 79917 NM_001099680 /// NM_001099681 /// NM_001099682 /// NM_024859 /// XM_005278062 /// XM_005278063 /// XM_005278064 /// XM_005278065 /// XM_006724560 /// XR_430508 219966_x_at NM_017869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017869.1 /DEF=Homo sapiens BANP homolog, SMAR1 homolog (FLJ20538), mRNA. /FEA=mRNA /GEN=FLJ20538 /PROD=BANP homolog, SMAR1 homolog /DB_XREF=gi:8923506 /UG=Hs.194637 BANP homolog, SMAR1 homolog /FL=gb:NM_017869.1 NM_017869 BTG3 associated nuclear protein BANP 54971 NM_001173539 /// NM_001173540 /// NM_001173541 /// NM_001173542 /// NM_001173543 /// NM_017869 /// NM_079837 /// XM_005256008 /// XM_005256009 /// XM_005256010 /// XM_005256012 /// XM_006721213 /// XM_006721214 /// XM_006721215 /// XM_006721216 /// XM_006721217 /// XM_006721218 /// XM_006721219 /// XM_006721220 /// XM_006721221 /// XM_006721222 /// XM_006721223 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0002039 // p53 binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 219967_at NM_024864 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024864.1 /DEF=Homo sapiens hypothetical protein FLJ22578 (FLJ22578), mRNA. /FEA=mRNA /GEN=FLJ22578 /PROD=hypothetical protein FLJ22578 /DB_XREF=gi:13376295 /UG=Hs.194864 hypothetical protein FLJ22578 /FL=gb:NM_024864.1 NM_024864 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) MRM1 79922 NM_024864 /// XM_005257694 /// XM_006722095 /// XM_006725349 /// XM_006725350 0001510 // RNA methylation // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219968_at NM_016089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016089.1 /DEF=Homo sapiens KRAB-zinc finger protein SZF1-1 (SZF1), mRNA. /FEA=mRNA /GEN=SZF1 /PROD=KRAB-zinc finger protein SZF1-1 /DB_XREF=gi:7706726 /UG=Hs.19585 KRAB-zinc finger protein SZF1-1 /FL=gb:AF114816.1 gb:NM_016089.1 NM_016089 zinc finger protein 589 ZNF589 51385 NM_016089 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219969_at NM_018360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018360.1 /DEF=Homo sapiens hypothetical protein FLJ11209 (FLJ11209), mRNA. /FEA=mRNA /GEN=FLJ11209 /PROD=hypothetical protein FLJ11209 /DB_XREF=gi:8922939 /UG=Hs.201624 hypothetical protein FLJ11209 /FL=gb:NM_018360.1 NM_018360 taxilin gamma TXLNG 55787 NM_001168683 /// NM_018360 /// XM_005274558 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0019905 // syntaxin binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 219970_at NM_017655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017655.1 /DEF=Homo sapiens hypothetical protein FLJ20075 (FLJ20075), mRNA. /FEA=mRNA /GEN=FLJ20075 /PROD=hypothetical protein FLJ20075 /DB_XREF=gi:8923083 /UG=Hs.205058 hypothetical protein FLJ20075 /FL=gb:NM_017655.1 NM_017655 GIPC PDZ domain containing family, member 2 GIPC2 54810 NM_017655 /// XM_005270956 /// XM_005270957 /// XM_005270958 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219971_at NM_021798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021798.1 /DEF=Homo sapiens interleukin 21 receptor (IL21R), mRNA. /FEA=mRNA /GEN=IL21R /PROD=interleukin 21 receptor /DB_XREF=gi:11141868 /UG=Hs.210546 interleukin 21 receptor /FL=gb:AF254067.1 gb:NM_021798.1 gb:BC004348.1 NM_021798 interleukin 21 receptor IL21R 50615 NM_021798 /// NM_181078 /// NM_181079 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030101 // natural killer cell activation // non-traceable author statement /// 0038114 // interleukin-21-mediated signaling pathway // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001532 // interleukin-21 receptor activity // non-traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 219972_s_at NM_022495 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022495.1 /DEF=Homo sapiens hypothetical protein FLJ12799 (FLJ12799), mRNA. /FEA=mRNA /GEN=FLJ12799 /PROD=hypothetical protein FLJ12799 /DB_XREF=gi:11968054 /UG=Hs.22549 hypothetical protein FLJ12799 /FL=gb:NM_022495.1 gb:AL136581.1 NM_022495 pecanex-like 4 (Drosophila) PCNXL4 64430 NM_022495 /// XM_005268009 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 219973_at NM_024590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024590.1 /DEF=Homo sapiens hypothetical protein FLJ23548 (FLJ23548), mRNA. /FEA=mRNA /GEN=FLJ23548 /PROD=hypothetical protein FLJ23548 /DB_XREF=gi:13375780 /UG=Hs.22895 hypothetical protein FLJ23548 /FL=gb:NM_024590.1 NM_024590 arylsulfatase family, member J ARSJ 79642 NM_024590 /// XM_005263211 /// XM_005263212 /// XM_005263213 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004065 // arylsulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219974_x_at NM_018479 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018479.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HCDASE (LOC55862), mRNA. /FEA=mRNA /GEN=LOC55862 /PROD=uncharacterized hypothalamus protein HCDASE /DB_XREF=gi:8923863 /UG=Hs.239218 uncharacterized hypothalamus protein HCDASE /FL=gb:AF220192.1 gb:NM_018479.1 NM_018479 enoyl CoA hydratase domain containing 1 ECHDC1 55862 NM_001002030 /// NM_001105544 /// NM_001105545 /// NM_001139510 /// NM_018479 /// XM_005267047 /// XM_005267048 /// XM_005267049 /// XM_005267050 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004492 // methylmalonyl-CoA decarboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from sequence or structural similarity 219975_x_at NM_018324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018324.1 /DEF=Homo sapiens hypothetical protein FLJ11106 (FLJ11106), mRNA. /FEA=mRNA /GEN=FLJ11106 /PROD=hypothetical protein FLJ11106 /DB_XREF=gi:8922870 /UG=Hs.24309 hypothetical protein FLJ11106 /FL=gb:NM_018324.1 NM_018324 oleoyl-ACP hydrolase OLAH 55301 NM_001039702 /// NM_018324 /// XM_006717456 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation 0004320 // oleoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016295 // myristoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016296 // palmitoyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016297 // acyl-[acyl-carrier-protein] hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 219976_at NM_015888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015888.1 /DEF=Homo sapiens hook1 protein (HOOK1), mRNA. /FEA=mRNA /GEN=HOOK1 /PROD=hook1 protein /DB_XREF=gi:7705414 /UG=Hs.250752 hook1 protein /FL=gb:AF044923.1 gb:NM_015888.1 NM_015888 hook microtubule-tethering protein 1 HOOK1 51361 NM_015888 /// XM_005270922 /// XM_006710676 /// XR_246271 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0070695 // FHF complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 219977_at NM_014336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014336.1 /DEF=Homo sapiens aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), mRNA. /FEA=mRNA /GEN=AIPL1 /PROD=aryl hydrocarbon receptor-interactingprotein-like 1 /DB_XREF=gi:7656880 /UG=Hs.279887 aryl hydrocarbon receptor-interacting protein-like 1 /FL=gb:NM_014336.1 gb:AF148864.1 NM_014336 aryl hydrocarbon receptor interacting protein-like 1 AIPL1 23746 NM_001033054 /// NM_001033055 /// NM_001285399 /// NM_001285400 /// NM_001285401 /// NM_001285402 /// NM_001285403 /// NM_014336 0001895 // retina homeostasis // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // inferred from electronic annotation /// 0018343 // protein farnesylation // inferred from direct assay /// 0030823 // regulation of cGMP metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001918 // farnesylated protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 219978_s_at NM_018454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018454.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM037 (BM037), mRNA. /FEA=mRNA /GEN=BM037 /PROD=uncharacterized bone marrow protein BM037 /DB_XREF=gi:8922094 /UG=Hs.283649 uncharacterized bone marrow protein BM037 /FL=gb:AF217513.1 gb:NM_018454.1 NM_018454 nucleolar and spindle associated protein 1 NUSAP1 51203 NM_001129897 /// NM_001243142 /// NM_001243143 /// NM_001243144 /// NM_016359 /// NM_018454 /// XM_005254428 /// XM_005254429 /// XM_005254430 /// XM_005254431 /// XM_006720559 /// XM_006720560 /// XM_006720561 /// XM_006720562 /// XM_006720563 0000070 // mitotic sister chromatid segregation // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000281 // mitotic cytokinesis // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0040001 // establishment of mitotic spindle localization // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 219979_s_at NM_016401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016401.1 /DEF=Homo sapiens hypothetical protein (HSPC138), mRNA. /FEA=mRNA /GEN=HSPC138 /PROD=hypothetical protein /DB_XREF=gi:7705470 /UG=Hs.283775 hypothetical protein /FL=gb:AF161487.1 gb:NM_016401.1 NM_016401 chromosome 11 open reading frame 73 C11orf73 51501 NM_016401 /// NR_024596 /// NR_024597 /// NR_024598 /// XM_006718582 /// XM_006718583 /// XM_006718584 0006606 // protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008565 // protein transporter activity // inferred from direct assay /// 0030544 // Hsp70 protein binding // inferred from direct assay 219980_at NM_025097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025097.1 /DEF=Homo sapiens hypothetical protein FLJ21106 (FLJ21106), mRNA. /FEA=mRNA /GEN=FLJ21106 /PROD=hypothetical protein FLJ21106 /DB_XREF=gi:13376659 /UG=Hs.288560 hypothetical protein FLJ21106 /FL=gb:NM_025097.1 NM_025097 chromosome 4 open reading frame 29 C4orf29 80167 NM_001039717 /// NM_025097 /// XM_005263238 /// XM_005263241 /// XM_005263242 /// XM_005263243 /// XM_006714318 /// XM_006714319 /// XM_006714320 /// XM_006714321 /// XM_006714322 /// XM_006714323 /// XM_006714324 /// XM_006714325 0005576 // extracellular region // inferred from electronic annotation 219981_x_at NM_017961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017961.1 /DEF=Homo sapiens hypothetical protein FLJ20813 (FLJ20813), mRNA. /FEA=mRNA /GEN=FLJ20813 /PROD=hypothetical protein FLJ20813 /DB_XREF=gi:8923685 /UG=Hs.306203 hypothetical protein FLJ20813 /FL=gb:NM_017961.1 NM_017961 zinc finger protein 587 ZNF587 84914 NM_001204817 /// NM_032828 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219982_s_at NM_022978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022978.1 /DEF=Homo sapiens small EDRK-rich factor 1B (centromeric) (SERF1B), mRNA. /FEA=mRNA /GEN=SERF1B /PROD=small EDRK-rich factor 1B, centromeric /DB_XREF=gi:13027631 /UG=Hs.306211 small EDRK-rich factor 1B (centromeric) /FL=gb:NM_022978.1 NM_022978 small EDRK-rich factor 1A (telomeric) /// small EDRK-rich factor 1B (centromeric) SERF1A /// SERF1B 8293 /// 728492 NM_001178087 /// NM_021967 /// NM_022968 /// NM_022978 0007399 // nervous system development // traceable author statement 219983_at NM_020386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020386.1 /DEF=Homo sapiens H-REV107 protein-related protein (LOC57110), mRNA. /FEA=mRNA /GEN=LOC57110 /PROD=H-REV107 protein-related protein /DB_XREF=gi:9966858 /UG=Hs.36761 H-REV107 protein-related protein /FL=gb:AB030816.1 gb:NM_020386.1 NM_020386 HRAS-like suppressor HRASLS 57110 NM_020386 /// XM_005247658 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0046485 // ether lipid metabolic process // inferred from electronic annotation 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219984_s_at NM_020386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020386.1 /DEF=Homo sapiens H-REV107 protein-related protein (LOC57110), mRNA. /FEA=mRNA /GEN=LOC57110 /PROD=H-REV107 protein-related protein /DB_XREF=gi:9966858 /UG=Hs.36761 H-REV107 protein-related protein /FL=gb:AB030816.1 gb:NM_020386.1 NM_020386 HRAS-like suppressor HRASLS 57110 NM_020386 /// XM_005247658 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0046485 // ether lipid metabolic process // inferred from electronic annotation 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 219985_at NM_006042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006042.1 /DEF=Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 (HS3ST3A1), mRNA. /FEA=mRNA /GEN=HS3ST3A1 /PROD=heparan sulfate D-glucosaminyl3-O-sulfotransferase 3A1 /DB_XREF=gi:5174464 /UG=Hs.48384 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 /FL=gb:AF105376.1 gb:NM_006042.1 NM_006042 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 HS3ST3A1 9955 NM_006042 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0033872 // [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity // inferred from electronic annotation 219986_s_at NM_025247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025247.1 /DEF=Homo sapiens hypothetical protein MGC5601 (MGC5601), mRNA. /FEA=mRNA /GEN=MGC5601 /PROD=hypothetical protein MGC5601 /DB_XREF=gi:13376863 /UG=Hs.64211 hypothetical protein MGC5601 /FL=gb:BC003698.1 gb:NM_025247.1 NM_025247 acyl-CoA dehydrogenase family, member 10 ACAD10 80724 NM_001136538 /// NM_001136542 /// NM_025247 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // non-traceable author statement 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 219987_at NM_024534 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024534.1 /DEF=Homo sapiens hypothetical protein FLJ12684 (FLJ12684), mRNA. /FEA=mRNA /GEN=FLJ12684 /PROD=hypothetical protein FLJ12684 /DB_XREF=gi:13375687 /UG=Hs.6933 hypothetical protein FLJ12684 /FL=gb:NM_024534.1 NM_024534 endogenous retrovirus group MER34, member 1 ERVMER34-1 100288413 NM_001242690 /// NM_024534 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019012 // virion // inferred from electronic annotation /// 0019031 // viral envelope // inferred from electronic annotation 219988_s_at NM_018150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018150.1 /DEF=Homo sapiens hypothetical protein FLJ10597 (FLJ10597), mRNA. /FEA=mRNA /GEN=FLJ10597 /PROD=hypothetical protein FLJ10597 /DB_XREF=gi:8922541 /UG=Hs.90375 hypothetical protein FLJ10597 /FL=gb:NM_018150.1 NM_018150 ring finger protein 220 RNF220 55182 NM_018150 /// XM_005270992 /// XM_005270993 /// XM_005270994 /// XM_005270996 /// XM_005270997 /// XM_006710735 0016567 // protein ubiquitination // inferred from sequence or structural similarity /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 219989_s_at NM_020140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020140.1 /DEF=Homo sapiens putative 47 kDa protein (LOC56899), mRNA. /FEA=mRNA /GEN=LOC56899 /PROD=putative 47 kDa protein /DB_XREF=gi:10047133 /UG=Hs.92927 putative 47 kDa protein /FL=gb:NM_020140.1 gb:AF164792.1 NM_020140 ankyrin repeat and sterile alpha motif domain containing 1B ANKS1B 56899 NM_001204065 /// NM_001204066 /// NM_001204067 /// NM_001204068 /// NM_001204069 /// NM_001204070 /// NM_001204079 /// NM_001204080 /// NM_001204081 /// NM_020140 /// NM_152788 /// NM_181670 /// XM_005269028 /// XM_005269029 /// XM_005269032 /// XM_006719504 /// XM_006719505 /// XM_006719506 /// XM_006719507 /// XM_006719508 /// XM_006719509 /// XM_006719510 /// XM_006719511 /// XM_006719512 /// XM_006719513 /// XM_006719514 /// XM_006719515 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 219990_at NM_024680 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024680.1 /DEF=Homo sapiens hypothetical protein FLJ23311 (FLJ23311), mRNA. /FEA=mRNA /GEN=FLJ23311 /PROD=hypothetical protein FLJ23311 /DB_XREF=gi:13375949 /UG=Hs.94292 hypothetical protein FLJ23311 /FL=gb:NM_024680.1 NM_024680 E2F transcription factor 8 E2F8 79733 NM_001256371 /// NM_001256372 /// NM_024680 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from sequence or structural similarity /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0032466 // negative regulation of cytokinesis // inferred from sequence or structural similarity /// 0032877 // positive regulation of DNA endoreduplication // inferred from sequence or structural similarity /// 0033301 // cell cycle comprising mitosis without cytokinesis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0060707 // trophoblast giant cell differentiation // inferred from sequence or structural similarity /// 0060718 // chorionic trophoblast cell differentiation // inferred from sequence or structural similarity /// 0070365 // hepatocyte differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 219991_at NM_020041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020041.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 9 (SLC2A9), mRNA. /FEA=mRNA /GEN=SLC2A9 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 9 /DB_XREF=gi:9910553 /UG=Hs.95497 solute carrier family 2 (facilitated glucose transporter), member 9 /FL=gb:AF210317.1 gb:NM_020041.1 NM_020041 solute carrier family 2 (facilitated glucose transporter), member 9 SLC2A9 56606 NM_001001290 /// NM_020041 /// XM_006713968 /// XM_006713969 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0015992 // proton transport // non-traceable author statement /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005635 // nuclear envelope // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005215 // transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // non-traceable author statement /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 219992_at NM_013251 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013251.1 /DEF=Homo sapiens tachykinin 3 (neuromedin K, neurokinin beta) (TAC3), mRNA. /FEA=mRNA /GEN=TAC3 /PROD=tachykinin 3 /DB_XREF=gi:7019576 /UG=Hs.9730 tachykinin 3 (neuromedin K, neurokinin beta) /FL=gb:AF186112.1 gb:NM_013251.1 gb:AF216586.1 NM_013251 tachykinin 3 TAC3 6866 NM_001006667 /// NM_001178054 /// NM_013251 /// NR_033654 /// XM_006719577 /// XM_006719578 /// XM_006719579 /// XM_006719580 0007217 // tachykinin receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 219993_at NM_022454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022454.1 /DEF=Homo sapiens hypothetical protein FLJ22252 similar to SRY-box containing gene 17 (FLJ22252), mRNA. /FEA=mRNA /GEN=FLJ22252 /PROD=hypothetical protein FLJ22252 similar to SRY-boxcontaining gene 17 /DB_XREF=gi:11967990 /UG=Hs.97984 hypothetical protein FLJ22252 similar to SRY-box containing gene 17 /FL=gb:NM_022454.1 NM_022454 SRY (sex determining region Y)-box 17 SOX17 64321 NM_022454 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001706 // endoderm formation // inferred from direct assay /// 0001828 // inner cell mass cellular morphogenesis // inferred from electronic annotation /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003142 // cardiogenic plate morphogenesis // inferred from sequence or structural similarity /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007493 // endodermal cell fate determination // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0042661 // regulation of mesodermal cell fate specification // inferred from electronic annotation /// 0042662 // negative regulation of mesodermal cell fate specification // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045995 // regulation of embryonic development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from sequence or structural similarity /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0048866 // stem cell fate specification // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060214 // endocardium formation // inferred from sequence or structural similarity /// 0060807 // regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification // inferred from sequence or structural similarity /// 0060913 // cardiac cell fate determination // inferred from mutant phenotype /// 0060914 // heart formation // traceable author statement /// 0060956 // endocardial cell differentiation // inferred from sequence or structural similarity /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061010 // gall bladder development // inferred from electronic annotation /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from mutant phenotype /// 0072091 // regulation of stem cell proliferation // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000035 // regulation of stem cell division // inferred from electronic annotation /// 2000043 // regulation of cardiac cell fate specification // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 219994_at NM_019043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019043.1 /DEF=Homo sapiens similar to proline-rich protein 48 (LOC54518), mRNA. /FEA=mRNA /GEN=LOC54518 /PROD=similar to proline-rich protein 48 /DB_XREF=gi:9506856 /UG=Hs.98874 similar to proline-rich protein 48 /FL=gb:NM_019043.1 NM_019043 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein APBB1IP 54518 NM_019043 /// XM_006717451 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 219995_s_at NM_024702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024702.1 /DEF=Homo sapiens hypothetical protein FLJ13841 (FLJ13841), mRNA. /FEA=mRNA /GEN=FLJ13841 /PROD=hypothetical protein FLJ13841 /DB_XREF=gi:13375990 /UG=Hs.99607 hypothetical protein FLJ13841 /FL=gb:NM_024702.1 NM_024702 zinc finger protein 750 ZNF750 79755 NM_024702 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0009308 // amine metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0008131 // primary amine oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation 219996_at NM_024708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024708.1 /DEF=Homo sapiens hypothetical protein FLJ22551 (FLJ22551), mRNA. /FEA=mRNA /GEN=FLJ22551 /PROD=hypothetical protein FLJ22551 /DB_XREF=gi:13376002 /UG=Hs.103041 hypothetical protein FLJ22551 /FL=gb:NM_024708.1 NM_024708 ankyrin repeat and SOCS box containing 7 ASB7 140460 NM_024708 /// NM_198243 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 219997_s_at NM_022730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022730.1 /DEF=Homo sapiens hypothetical protein FLJ12612 similar to COP9 (constitutive photomorphogenic), subunit 7b (Arabidopsis) (FLJ12612), mRNA. /FEA=mRNA /GEN=FLJ12612 /PROD=hypothetical protein FLJ12612 similar to COP9(constitutive photomorphogenic), subunit 7b (Arabidopsis) /DB_XREF=gi:12232384 /UG=Hs.114432 hypothetical protein FLJ12612 similar to COP9 (constitutive photomorphogenic), subunit 7b (Arabidopsis) /FL=gb:NM_022730.1 NM_022730 COP9 signalosome subunit 7B COPS7B 64708 NM_001282949 /// NM_001282950 /// NM_001282951 /// NM_001282952 /// NM_022730 /// XM_006712692 /// XM_006712693 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 219998_at NM_014181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014181.1 /DEF=Homo sapiens HSPC159 protein (HSPC159), mRNA. /FEA=mRNA /GEN=HSPC159 /PROD=HSPC159 protein /DB_XREF=gi:7661817 /UG=Hs.114771 HSPC159 protein /FL=gb:AF161508.1 gb:NM_014181.1 NM_014181 lectin, galactoside-binding-like LGALSL 29094 NM_014181 0005622 // intracellular // inferred from direct assay 0030246 // carbohydrate binding // inferred from electronic annotation 219999_at NM_018621 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018621.1 /DEF=Homo sapiens hypothetical protein PRO2198 (PRO2198), mRNA. /FEA=mRNA /GEN=PRO2198 /PROD=hypothetical protein PRO2198 /DB_XREF=gi:8924129 /UG=Hs.116459 hypothetical protein PRO2198 /FL=gb:AF116691.1 gb:NM_018621.1 NM_018621 mannosidase, alpha, class 2A, member 2 MAN2A2 4122 NM_006122 /// XM_005254910 /// XM_005254911 /// XM_006720507 /// XR_243208 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0004572 // mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220000_at NM_003830 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003830.1 /DEF=Homo sapiens sialic acid binding Ig-like lectin 5 (SIGLEC5), mRNA. /FEA=mRNA /GEN=SIGLEC5 /PROD=sialic acid binding Ig-like lectin 5 /DB_XREF=gi:4502658 /UG=Hs.117005 sialic acid binding Ig-like lectin 5 /FL=gb:U71383.1 gb:NM_003830.1 gb:AF170484.1 NM_003830 sialic acid binding Ig-like lectin 5 SIGLEC5 8778 NM_003830 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220001_at NM_012387 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012387.1 /DEF=Homo sapiens peptidyl arginine deiminase, type V (PAD), mRNA. /FEA=mRNA /GEN=PAD /PROD=peptidyl arginine deiminase, type V /DB_XREF=gi:6912575 /UG=Hs.117232 peptidyl arginine deiminase, type V /FL=gb:AB017919.1 gb:NM_012387.1 NM_012387 peptidyl arginine deiminase, type IV PADI4 23569 NM_012387 0002376 // immune system process // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0016568 // chromatin modification // inferred from sequence or structural similarity /// 0018101 // protein citrullination // inferred from direct assay /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0036413 // histone H3-R26 citrullination // inferred from direct assay /// 0036414 // histone citrullination // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004668 // protein-arginine deiminase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016990 // arginine deiminase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220002_at NM_018012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018012.1 /DEF=Homo sapiens hypothetical protein FLJ10157 (FLJ10157), mRNA. /FEA=mRNA /GEN=FLJ10157 /PROD=hypothetical protein FLJ10157 /DB_XREF=gi:8922260 /UG=Hs.125020 hypothetical protein FLJ10157 /FL=gb:NM_018012.1 NM_018012 kinesin family member 26B KIF26B 55083 NM_018012 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0072092 // ureteric bud invasion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 220003_at NM_018296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018296.1 /DEF=Homo sapiens hypothetical protein FLJ11004 (FLJ11004), mRNA. /FEA=mRNA /GEN=FLJ11004 /PROD=hypothetical protein FLJ11004 /DB_XREF=gi:8922815 /UG=Hs.125139 hypothetical protein FLJ11004 /FL=gb:NM_018296.1 NM_018296 leucine rich repeat containing 36 LRRC36 55282 NM_001161575 /// NM_018296 /// XM_005256025 /// XM_005256026 /// XM_005256027 /// XM_005256028 /// XR_243416 /// XR_429723 220004_at NM_018665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018665.1 /DEF=Homo sapiens DEAD-box protein (HAGE), mRNA. /FEA=mRNA /GEN=HAGE /PROD=DEAD-box protein /DB_XREF=gi:10346128 /UG=Hs.125507 DEAD-box protein /FL=gb:NM_018665.1 gb:AL136751.1 NM_018665 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 DDX43 55510 NM_018665 /// XM_006715508 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220005_at NM_023914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023914.1 /DEF=Homo sapiens G protein-coupled receptor 86 (GPR86), mRNA. /FEA=mRNA /GEN=GPR86 /PROD=G protein-coupled receptor 86 /DB_XREF=gi:13194202 /UG=Hs.13040 G protein-coupled receptor 86 /FL=gb:AF295368.1 gb:NM_023914.1 gb:AF178982.1 gb:AF345565.1 NM_023914 purinergic receptor P2Y, G-protein coupled, 13 P2RY13 53829 NM_023914 /// NM_176894 /// XM_006713664 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation 220006_at NM_024768 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024768.1 /DEF=Homo sapiens hypothetical protein FLJ12057 (FLJ12057), mRNA. /FEA=mRNA /GEN=FLJ12057 /PROD=hypothetical protein FLJ12057 /DB_XREF=gi:13376112 /UG=Hs.134807 hypothetical protein FLJ12057 /FL=gb:NM_024768.1 NM_024768 EF-hand and coiled-coil domain containing 1 EFCC1 79825 NM_024768 /// XM_005247781 0005509 // calcium ion binding // inferred from electronic annotation 220007_at NM_024770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024770.1 /DEF=Homo sapiens hypothetical protein FLJ13984 (FLJ13984), mRNA. /FEA=mRNA /GEN=FLJ13984 /PROD=hypothetical protein FLJ13984 /DB_XREF=gi:13376116 /UG=Hs.135146 hypothetical protein FLJ13984 /FL=gb:NM_024770.1 NM_024770 methyltransferase like 8 METTL8 79828 NM_024770 /// XM_006712762 /// XM_006712763 /// XM_006712764 /// XM_006712765 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 220008_at NM_024776 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024776.1 /DEF=Homo sapiens hypothetical protein FLJ21140 (FLJ21140), mRNA. /FEA=mRNA /GEN=FLJ21140 /PROD=hypothetical protein FLJ21140 /DB_XREF=gi:13376128 /UG=Hs.143895 hypothetical protein FLJ21140 /FL=gb:NM_024776.1 NM_024776 pseudopodium-enriched atypical kinase 1 PEAK1 79834 NM_024776 /// XM_005254670 /// XM_005254671 /// XM_005254672 /// XM_005254673 /// XM_005254674 /// XM_005254675 /// XM_006720691 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220009_at NM_024778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024778.1 /DEF=Homo sapiens hypothetical protein FLJ22612 (FLJ22612), mRNA. /FEA=mRNA /GEN=FLJ22612 /PROD=hypothetical protein FLJ22612 /DB_XREF=gi:13376133 /UG=Hs.144266 hypothetical protein FLJ22612 /FL=gb:NM_024778.1 NM_024778 LON peptidase N-terminal domain and ring finger 3 LONRF3 79836 NM_001031855 /// NM_001289109 /// NM_024778 /// NR_110311 /// XM_005262476 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220010_at NM_012282 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012282.1 /DEF=Homo sapiens potassium voltage-gated channel, Isk-related family, member 1-like (KCNE1L), mRNA. /FEA=mRNA /GEN=KCNE1L /PROD=potassium voltage-gated channel, Isk-relatedfamily, member 1-like /DB_XREF=gi:6912441 /UG=Hs.146372 potassium voltage-gated channel, Isk-related family, member 1-like /FL=gb:NM_012282.1 NM_012282 KCNE1-like KCNE1L 23630 NM_012282 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0060372 // regulation of atrial cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from direct assay /// 2001257 // regulation of cation channel activity // inferred from direct assay 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype 220011_at NM_024037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024037.1 /DEF=Homo sapiens hypothetical protein MGC2603 (MGC2603), mRNA. /FEA=mRNA /GEN=MGC2603 /PROD=hypothetical protein MGC2603 /DB_XREF=gi:13128989 /UG=Hs.149305 hypothetical protein MGC2603 /FL=gb:BC000209.1 gb:NM_024037.1 NM_024037 aurora kinase A and ninein interacting protein AUNIP 79000 NM_001287490 /// NM_024037 0007051 // spindle organization // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220012_at NM_019891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019891.1 /DEF=Homo sapiens endoplasmic reticulum oxidoreductin 1-Lbeta (ERO1-L(BETA)), mRNA. /FEA=mRNA /GEN=ERO1-L(BETA) /PROD=endoplasmic reticulum oxidoreductin 1-Lbeta /DB_XREF=gi:9845248 /UG=Hs.150763 endoplasmic reticulum oxidoreductin 1-Lbeta /FL=gb:AF252538.1 gb:NM_019891.1 NM_019891 ERO1-like beta (S. cerevisiae) ERO1LB 56605 NM_019891 0006457 // protein folding // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 220013_at NM_024794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024794.1 /DEF=Homo sapiens hypothetical protein FLJ22408 (FLJ22408), mRNA. /FEA=mRNA /GEN=FLJ22408 /PROD=hypothetical protein FLJ22408 /DB_XREF=gi:13376163 /UG=Hs.156457 hypothetical protein FLJ22408 /FL=gb:NM_024794.1 NM_024794 epoxide hydrolase 3 EPHX3 79852 NM_001142886 /// NM_024794 /// XM_006722900 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220014_at NM_016644 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016644.1 /DEF=Homo sapiens mesenchymal stem cell protein DSC54 (LOC51334), mRNA. /FEA=mRNA /GEN=LOC51334 /PROD=mesenchymal stem cell protein DSC54 /DB_XREF=gi:7706193 /UG=Hs.157461 mesenchymal stem cell protein DSC54 /FL=gb:AF242769.1 gb:NM_016644.1 NM_016644 proline rich 16 PRR16 51334 NM_016644 /// XM_005272010 /// XM_005272011 /// XM_005272012 220015_at NM_017766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017766.1 /DEF=Homo sapiens hypothetical protein FLJ20321 (FLJ20321), mRNA. /FEA=mRNA /GEN=FLJ20321 /PROD=hypothetical protein FLJ20321 /DB_XREF=gi:8923302 /UG=Hs.162196 hypothetical protein FLJ20321 /FL=gb:BC004410.1 gb:NM_017766.1 NM_017766 castor zinc finger 1 CASZ1 54897 NM_001039183 /// NM_001079843 /// NM_017766 /// XM_005263479 /// XM_006710712 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220016_at NM_024060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024060.1 /DEF=Homo sapiens hypothetical protein MGC5395 (MGC5395), mRNA. /FEA=mRNA /GEN=MGC5395 /PROD=hypothetical protein MGC5395 /DB_XREF=gi:13129033 /UG=Hs.165215 hypothetical protein MGC5395 /FL=gb:BC000926.1 gb:NM_024060.1 NM_024060 AHNAK nucleoprotein AHNAK 79026 NM_001620 /// NM_024060 /// XM_005274240 /// XM_005274241 /// XM_005274242 /// XM_005274243 /// XM_005274244 /// XM_005274245 /// XM_005274246 /// XM_006718686 /// XM_006718687 /// XM_006718688 0007399 // nervous system development // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from sequence or structural similarity /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030315 // T-tubule // non-traceable author statement /// 0031982 // vesicle // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0042383 // sarcolemma // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097493 // structural molecule activity conferring elasticity // inferred from sequence or structural similarity 220017_x_at NM_000771 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000771.2 /DEF=Homo sapiens cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 (CYP2C9), mRNA. /FEA=mRNA /GEN=CYP2C9 /PROD=cytochrome P450, subfamily IIC, polypeptide 9 /DB_XREF=gi:13699817 /UG=Hs.167529 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 /FL=gb:NM_000771.2 NM_000771 cytochrome P450, family 2, subfamily C, polypeptide 9 CYP2C9 1559 NM_000771 /// XM_006717644 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0019627 // urea metabolic process // inferred from direct assay /// 0032787 // monocarboxylic acid metabolic process // inferred from direct assay /// 0042737 // drug catabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0043603 // cellular amide metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070989 // oxidative demethylation // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0034875 // caffeine oxidase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation 220018_at NM_024814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024814.1 /DEF=Homo sapiens hypothetical protein FLJ23109 (FLJ23109), mRNA. /FEA=mRNA /GEN=FLJ23109 /PROD=hypothetical protein FLJ23109 /DB_XREF=gi:13376203 /UG=Hs.170101 hypothetical protein FLJ23109 /FL=gb:NM_024814.1 NM_024814 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase CBLL1 79872 NM_001284291 /// NM_024814 /// NR_024199 /// XM_006716132 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045807 // positive regulation of endocytosis // inferred from sequence or structural similarity 0000151 // ubiquitin ligase complex // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220019_s_at NM_005774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005774.1 /DEF=Homo sapiens zinc finger protein 255 (ZNF255), mRNA. /FEA=mRNA /GEN=ZNF255 /PROD=zinc finger protein 255 /DB_XREF=gi:5031614 /UG=Hs.181696 zinc finger protein 255 /FL=gb:AF067164.1 gb:NM_005774.1 NM_005774 zinc finger protein 224 ZNF224 7767 NM_013398 /// XM_005259221 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220020_at NM_022098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022098.1 /DEF=Homo sapiens hypothetical protein LOC63929 (LOC63929), mRNA. /FEA=mRNA /GEN=LOC63929 /PROD=hypothetical protein LOC63929 /DB_XREF=gi:11559924 /UG=Hs.182061 hypothetical protein LOC63929 /FL=gb:NM_022098.1 gb:BC001681.1 gb:BC004989.1 NM_022098 X-prolyl aminopeptidase (aminopeptidase P) 3, putative XPNPEP3 63929 NM_001204827 /// NM_022098 0003094 // glomerular filtration // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220021_at NM_024847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024847.1 /DEF=Homo sapiens hypothetical protein FLJ21240 (FLJ21240), mRNA. /FEA=mRNA /GEN=FLJ21240 /PROD=hypothetical protein FLJ21240 /DB_XREF=gi:13376264 /UG=Hs.187377 hypothetical protein FLJ21240 /FL=gb:NM_024847.1 NM_024847 transmembrane channel-like 7 TMC7 79905 NM_001160364 /// NM_024847 /// XM_005255597 /// XM_005255600 /// XM_006721094 /// XM_006721095 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220022_at NM_018102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018102.1 /DEF=Homo sapiens hypothetical protein FLJ10469 (FLJ10469), mRNA. /FEA=mRNA /GEN=FLJ10469 /PROD=hypothetical protein FLJ10469 /DB_XREF=gi:8922439 /UG=Hs.192662 hypothetical protein FLJ10469 /FL=gb:NM_018102.1 NM_018102 zinc finger protein 334 ZNF334 55713 NM_001270497 /// NM_018102 /// NM_199441 /// NR_073026 /// XM_005260447 /// XM_006723816 /// XM_006723817 /// XM_006723818 /// XM_006723819 /// XM_006723820 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220023_at NM_018690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018690.1 /DEF=Homo sapiens apolipoprotein B48 receptor (APOB48R), mRNA. /FEA=mRNA /GEN=APOB48R /PROD=apolipoprotein B48 receptor /DB_XREF=gi:8922078 /UG=Hs.200333 apolipoprotein B48 receptor /FL=gb:AF141332.1 gb:AF141334.1 gb:NM_018690.1 NM_018690 apolipoprotein B receptor APOBR 55911 NM_018690 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation 0030226 // apolipoprotein receptor activity // inferred from direct assay /// 0030228 // lipoprotein particle receptor activity // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 220024_s_at NM_020956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020956.1 /DEF=Homo sapiens periaxin (KIAA1620), mRNA. /FEA=mRNA /GEN=KIAA1620 /PROD=periaxin /DB_XREF=gi:13491171 /UG=Hs.205457 periaxin /FL=gb:AF321192.1 gb:NM_020956.1 NM_020956 periaxin PRX 57716 NM_020956 /// NM_181882 /// XM_005259111 0008219 // cell death // inferred from electronic annotation /// 0008366 // axon ensheathment // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220025_at NM_006593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006593.1 /DEF=Homo sapiens T-box, brain, 1 (TBR1), mRNA. /FEA=mRNA /GEN=TBR1 /PROD=T-box, brain, 1 /DB_XREF=gi:5730080 /UG=Hs.210862 T-box, brain, 1 /FL=gb:U49250.1 gb:NM_006593.1 NM_006593 T-box, brain, 1 TBR1 10716 NM_006593 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0010092 // specification of organ identity // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 220026_at NM_012128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012128.2 /DEF=Homo sapiens chloride channel, calcium activated, family member 4 (CLCA4), mRNA. /FEA=mRNA /GEN=CLCA4 /PROD=calcium activated chloride channel 4 /DB_XREF=gi:12025666 /UG=Hs.227059 chloride channel, calcium activated, family member 4 /FL=gb:NM_012128.2 gb:AF127035.1 NM_012128 chloride channel accessory 4 CLCA4 22802 NM_012128 /// NR_024602 /// XM_006710453 0006810 // transport // traceable author statement /// 0006821 // chloride transport // traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220027_s_at NM_017805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017805.1 /DEF=Homo sapiens hypothetical protein FLJ20401 (FLJ20401), mRNA. /FEA=mRNA /GEN=FLJ20401 /PROD=hypothetical protein FLJ20401 /DB_XREF=gi:8923375 /UG=Hs.233955 hypothetical protein FLJ20401 /FL=gb:NM_017805.1 NM_017805 Ras interacting protein 1 RASIP1 54922 NM_017805 /// XM_005259023 /// XM_005259024 /// XM_006723250 /// XM_006723251 /// XM_006723252 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0048754 // branching morphogenesis of an epithelial tube // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220028_at NM_001106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001106.2 /DEF=Homo sapiens activin A receptor, type IIB (ACVR2B), mRNA. /FEA=mRNA /GEN=ACVR2B /PROD=activin A type IIB receptor precursor /DB_XREF=gi:10862697 /UG=Hs.23994 activin A receptor, type IIB /FL=gb:NM_001106.2 NM_001106 activin A receptor, type IIB ACVR2B 93 NM_001106 /// XM_005265583 0001501 // skeletal system development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from mutant phenotype /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0031016 // pancreas development // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0032924 // activin receptor signaling pathway // traceable author statement /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060836 // lymphatic endothelial cell differentiation // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from sequence or structural similarity /// 0060841 // venous blood vessel development // inferred from sequence or structural similarity /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016362 // activin receptor activity, type II // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017002 // activin-activated receptor activity // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0034711 // inhibin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from electronic annotation 220029_at NM_017770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017770.1 /DEF=Homo sapiens elongation of very long chain fatty acids (FEN1Elo2, SUR4Elo3, yeast)-like 2 (ELOVL2), mRNA. /FEA=mRNA /GEN=ELOVL2 /PROD=elongation of very long chain fatty acids(FEN1Elo2, SUR4Elo3, yeast)-like 2 /DB_XREF=gi:8923311 /UG=Hs.246107 elongation of very long chain fatty acids (FEN1Elo2, SUR4Elo3, yeast)-like 2 /FL=gb:NM_017770.1 NM_017770 ELOVL fatty acid elongase 2 ELOVL2 54898 NM_017770 /// XM_005249200 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034626 // fatty acid elongation, polyunsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 220030_at NM_018423 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018423.1 /DEF=Homo sapiens hypothetical protein DKFZp761P1010 (DKFZp761P1010), mRNA. /FEA=mRNA /GEN=DKFZp761P1010 /PROD=hypothetical protein DKFZp761P1010 /DB_XREF=gi:8922178 /UG=Hs.24979 hypothetical protein DKFZp761P1010 /FL=gb:NM_018423.1 NM_018423 serine/threonine/tyrosine kinase 1 STYK1 55359 NM_018423 /// XM_005253417 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220031_at NM_020205 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020205.1 /DEF=Homo sapiens zinc finger protein Cezanne (CEZANNE), mRNA. /FEA=mRNA /GEN=CEZANNE /PROD=zinc finger protein Cezanne /DB_XREF=gi:9910155 /UG=Hs.252731 zinc finger protein Cezanne /FL=gb:NM_020205.1 NM_020205 OTU deubiquitinase 7B OTUD7B 56957 NM_020205 /// XM_005277414 /// XM_006711461 /// XM_006711462 /// XM_006711463 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002385 // mucosal immune response // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from electronic annotation /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from sequence or structural similarity /// 1900181 // negative regulation of protein localization to nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from sequence or structural similarity /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from electronic annotation /// 1990380 // Lys48-specific deubiquitinase activity // inferred from direct assay 220032_at NM_024913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024913.1 /DEF=Homo sapiens hypothetical protein FLJ21986 (FLJ21986), mRNA. /FEA=mRNA /GEN=FLJ21986 /PROD=hypothetical protein FLJ21986 /DB_XREF=gi:13376377 /UG=Hs.255416 hypothetical protein FLJ21986 /FL=gb:NM_024913.1 NM_024913 cadherin-like and PC-esterase domain containing 1 CPED1 79974 NM_001105533 /// NM_024913 0005783 // endoplasmic reticulum // inferred from direct assay 220033_at NM_024601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024601.1 /DEF=Homo sapiens hypothetical protein FLJ21031 (FLJ21031), mRNA. /FEA=mRNA /GEN=FLJ21031 /PROD=hypothetical protein FLJ21031 /DB_XREF=gi:13375802 /UG=Hs.25982 hypothetical protein FLJ21031 /FL=gb:NM_024601.1 NM_024601 220034_at NM_007199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007199.1 /DEF=Homo sapiens interleukin-1 receptor-associated kinase M (IRAK-M), mRNA. /FEA=mRNA /GEN=IRAK-M /PROD=interleukin-1 receptor-associated kinase M /DB_XREF=gi:6005791 /UG=Hs.268552 interleukin-1 receptor-associated kinase M /FL=gb:AF113136.1 gb:NM_007199.1 NM_007199 interleukin-1 receptor-associated kinase 3 IRAK3 11213 NM_001142523 /// NM_007199 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred by curator /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0009615 // response to virus // inferred by curator /// 0010933 // positive regulation of macrophage tolerance induction // inferred from sequence or structural similarity /// 0010936 // negative regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032494 // response to peptidoglycan // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from mutant phenotype /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0043244 // regulation of protein complex disassembly // inferred from sequence or structural similarity /// 0043330 // response to exogenous dsRNA // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 220035_at NM_024923 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024923.1 /DEF=Homo sapiens hypothetical protein FLJ22389 (FLJ22389), mRNA. /FEA=mRNA /GEN=FLJ22389 /PROD=hypothetical protein FLJ22389 /DB_XREF=gi:13376397 /UG=Hs.270404 hypothetical protein FLJ22389 /FL=gb:NM_024923.1 NM_024923 nucleoporin 210kDa NUP210 23225 NM_024923 /// XM_005264994 /// XR_245105 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0046983 // protein dimerization activity // inferred from electronic annotation 220036_s_at NM_018113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018113.1 /DEF=Homo sapiens hypothetical protein FLJ10494 (FLJ10494), mRNA. /FEA=mRNA /GEN=FLJ10494 /PROD=hypothetical protein FLJ10494 /DB_XREF=gi:8922462 /UG=Hs.272838 hypothetical protein FLJ10494 /FL=gb:NM_018113.1 NM_018113 limb development membrane protein 1-like LMBR1L 55716 NM_018113 /// XM_005269022 /// XM_005269023 /// XM_006719501 /// XM_006719502 /// XR_245944 0006897 // endocytosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220037_s_at NM_016164 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016164.2 /DEF=Homo sapiens hyaluronic acid receptor (HAR), mRNA. /FEA=mRNA /GEN=HAR /PROD=hyaluronic acid receptor /DB_XREF=gi:10835259 /UG=Hs.278975 hyaluronic acid receptor /FL=gb:AF127670.2 gb:NM_016164.2 NM_016164 lymphatic vessel endothelial hyaluronan receptor 1 LYVE1 10894 NM_006691 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation 220038_at NM_013257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013257.1 /DEF=Homo sapiens serumglucocorticoid regulated kinase-like (SGKL), mRNA. /FEA=mRNA /GEN=SGKL /PROD=serumglucocorticoid regulated kinase-like /DB_XREF=gi:7019526 /UG=Hs.279696 serumglucocorticoid regulated kinase-like /FL=gb:AF169035.1 gb:AF085233.1 gb:NM_013257.1 NM_013257 C8orf44-SGK3 readthrough /// serum/glucocorticoid regulated kinase family, member 3 C8orf44-SGK3 /// SGK3 23678 /// 100533105 NM_001033578 /// NM_001204173 /// NM_013257 /// NM_170709 0001558 // regulation of cell growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // traceable author statement /// 0017081 // chloride channel regulator activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 220039_s_at NM_017774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017774.1 /DEF=Homo sapiens hypothetical protein FLJ20342 (FLJ20342), mRNA. /FEA=mRNA /GEN=FLJ20342 /PROD=hypothetical protein FLJ20342 /DB_XREF=gi:8923317 /UG=Hs.279893 hypothetical protein FLJ20342 /FL=gb:NM_017774.1 NM_017774 CDK5 regulatory subunit associated protein 1-like 1 CDKAL1 54901 NM_017774 /// XM_006715127 /// XM_006715128 0008033 // tRNA processing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0035600 // tRNA methylthiolation // inferred from electronic annotation /// 0043412 // macromolecule modification // inferred from electronic annotation /// 1990145 // maintenance of translational fidelity // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035598 // N6-threonylcarbomyladenosine methylthiotransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 220040_x_at NM_018684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018684.1 /DEF=Homo sapiens hepatocellular carcinoma-associated antigen 127 (HCA127), mRNA. /FEA=mRNA /GEN=HCA127 /PROD=hepatocellular carcinoma-associated antigen 127 /DB_XREF=gi:8923719 /UG=Hs.28249 hepatocellular carcinoma-associated antigen 127 /FL=gb:BC004411.1 gb:AF270491.1 gb:NM_018684.1 NM_018684 zinc finger, C4H2 domain containing ZC4H2 55906 NM_001178032 /// NM_001178033 /// NM_001243804 /// NM_018684 /// NR_045044 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from direct assay /// 0007528 // neuromuscular junction development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 220041_at NM_025163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025163.1 /DEF=Homo sapiens hypothetical protein FLJ12768 (FLJ12768), mRNA. /FEA=mRNA /GEN=FLJ12768 /PROD=hypothetical protein FLJ12768 /DB_XREF=gi:13376764 /UG=Hs.289077 hypothetical protein FLJ12768 /FL=gb:NM_025163.1 NM_025163 phosphatidylinositol glycan anchor biosynthesis, class Z PIGZ 80235 NM_025163 /// XM_006713758 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006506 // GPI anchor biosynthetic process // inferred from genetic interaction /// 0006506 // GPI anchor biosynthetic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0097502 // mannosylation // inferred from genetic interaction /// 0097502 // mannosylation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000026 // alpha-1,2-mannosyltransferase activity // inferred from mutant phenotype /// 0000030 // mannosyltransferase activity // inferred from genetic interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220042_x_at NM_024503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024503.1 /DEF=Homo sapiens human immunodeficiency virus type I enhancer-binding protein 3 (HIVEP3), mRNA. /FEA=mRNA /GEN=HIVEP3 /PROD=human immunodeficiency virus type Ienhancer-binding protein 3 /DB_XREF=gi:13375633 /UG=Hs.306213 human immunodeficiency virus type I enhancer-binding protein 3 /FL=gb:AF278765.1 gb:NM_024503.1 NM_024503 human immunodeficiency virus type I enhancer binding protein 3 HIVEP3 59269 NM_001127714 /// NM_024503 /// NR_038260 /// NR_038261 /// XM_006710808 /// XM_006710809 /// XR_426625 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220043_s_at NM_005929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005929.2 /DEF=Homo sapiens antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 (MFI2), mRNA. /FEA=mRNA /GEN=MFI2 /PROD=melanoma-associated antigen p97 precursor /DB_XREF=gi:5729923 /UG=Hs.313697 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 /FL=gb:NM_005929.2 NM_005929 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 MFI2 4241 NM_005929 /// NM_033316 /// XM_006713642 /// XM_006713643 /// XM_006713644 0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0010756 // positive regulation of plasminogen activation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0090091 // positive regulation of extracellular matrix disassembly // inferred from direct assay /// 0097286 // iron ion import // inferred from mutant phenotype /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220044_x_at NM_016424 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016424.1 /DEF=Homo sapiens cisplatin resistance-associated overexpressed protein (LUC7A), mRNA. /FEA=mRNA /GEN=LUC7A /PROD=cisplatin resistance-associated overexpressedprotein /DB_XREF=gi:7706534 /UG=Hs.3688 cisplatin resistance-associated overexpressed protein /FL=gb:NM_016424.1 NM_016424 LUC7-like 3 (S. cerevisiae) LUC7L3 51747 NM_006107 /// NM_016424 /// XM_005257448 /// XM_005257449 /// XM_005257450 /// XM_005257451 /// XM_005257452 /// XM_005257454 /// XM_005257455 /// XM_006721943 /// XR_243663 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 220045_at NM_022728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022728.1 /DEF=Homo sapiens neurogenic differentiation 6 (NEUROD6), mRNA. /FEA=mRNA /GEN=NEUROD6 /PROD=neurogenic differentiation 6 /DB_XREF=gi:12232382 /UG=Hs.45152 neurogenic differentiation 6 /FL=gb:AF063609.1 gb:NM_022728.1 NM_022728 neuronal differentiation 6 NEUROD6 63974 NM_022728 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220046_s_at NM_020307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020307.1 /DEF=Homo sapiens cyclin L ania-6a (LOC57018), mRNA. /FEA=mRNA /GEN=LOC57018 /PROD=cyclin L ania-6a /DB_XREF=gi:9945319 /UG=Hs.4859 cyclin L ania-6a /FL=gb:AF180920.1 gb:NM_020307.1 NM_020307 cyclin L1 CCNL1 57018 NM_020307 /// XM_005247647 /// XM_005247648 /// XM_005247649 /// XM_005247650 /// XM_005247651 /// XM_006713710 /// XM_006713711 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 220047_at NM_012240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012240.1 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 4 (SIRT4), mRNA. /FEA=mRNA /GEN=SIRT4 /PROD=sirtuin 4 /DB_XREF=gi:6912661 /UG=Hs.50861 sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 4 /FL=gb:AF083109.1 gb:NM_012240.1 NM_012240 sirtuin 4 SIRT4 23409 NM_012240 /// XM_005253865 /// XM_006719308 /// XM_006719309 /// XM_006719310 /// XM_006719311 /// XM_006719312 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // inferred from sequence or structural similarity /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0034983 // peptidyl-lysine deacetylation // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034979 // NAD-dependent protein deacetylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 220048_at NM_022336 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022336.1 /DEF=Homo sapiens ectodysplasin 1, anhidrotic receptor (EDAR), mRNA. /FEA=mRNA /GEN=EDAR /PROD=ectodysplasin 1, anhidrotic receptor /DB_XREF=gi:11641230 /UG=Hs.58346 ectodysplasin 1, anhidrotic receptor /FL=gb:NM_022336.1 gb:AF130988.1 NM_022336 ectodysplasin A receptor EDAR 10913 NM_022336 /// XM_006712204 0001942 // hair follicle development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0045177 // apical part of cell // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220049_s_at NM_025239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025239.1 /DEF=Homo sapiens programmed death ligand 2 (PDL2), mRNA. /FEA=mRNA /GEN=PDL2 /PROD=programmed death ligand 2 /DB_XREF=gi:13376849 /UG=Hs.61929 programmed death ligand 2 /FL=gb:AF344424.1 gb:NM_025239.1 NM_025239 programmed cell death 1 ligand 2 PDCD1LG2 80380 NM_025239 /// XM_005251600 /// XM_005251601 /// XM_005251602 0006955 // immune response // non-traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 220050_at NM_018956 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018956.1 /DEF=Homo sapiens chromosome 9 open reading frame 9 (C9ORF9), mRNA. /FEA=mRNA /GEN=C9ORF9 /PROD=chromosome 9 open reading frame 9 /DB_XREF=gi:9506440 /UG=Hs.62595 chromosome 9 open reading frame 9 /FL=gb:NM_018956.1 NM_018956 chromosome 9 open reading frame 9 C9orf9 11092 NM_018956 /// XM_005272164 0005881 // cytoplasmic microtubule // inferred from direct assay 220051_at NM_006799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006799.1 /DEF=Homo sapiens protease, serine, 21 (testisin) (PRSS21), mRNA. /FEA=mRNA /GEN=PRSS21 /PROD=protease, serine, 21 (testisin) /DB_XREF=gi:5803196 /UG=Hs.72026 protease, serine, 21 (testisin) /FL=gb:AF058300.1 gb:AB031329.1 gb:AB031330.1 gb:NM_006799.1 gb:AB031331.1 NM_006799 protease, serine, 21 (testisin) PRSS21 10942 NM_001270452 /// NM_006799 /// NM_144956 /// NM_144957 /// NR_073012 /// XM_005255051 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 220052_s_at NM_012461 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012461.1 /DEF=Homo sapiens TERF1 (TRF1)-interacting nuclear factor 2 (TINF2), mRNA. /FEA=mRNA /GEN=TINF2 /PROD=TERF1 (TRF1)-interacting nuclear factor 2 /DB_XREF=gi:6912715 /UG=Hs.7797 TERF1 (TRF1)-interacting nuclear factor 2 /FL=gb:AF195512.1 gb:NM_012461.1 NM_012461 TERF1 (TRF1)-interacting nuclear factor 2 TINF2 26277 NM_001099274 /// NM_012461 /// XM_005267528 /// XM_005267529 0000723 // telomere maintenance // traceable author statement /// 0010833 // telomere maintenance via telomere lengthening // inferred from mutant phenotype /// 0010836 // negative regulation of protein ADP-ribosylation // inferred from genetic interaction /// 0032202 // telomere assembly // inferred from mutant phenotype /// 0032205 // negative regulation of telomere maintenance // inferred from electronic annotation /// 0032206 // positive regulation of telomere maintenance // inferred from mutant phenotype /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred by curator /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0034502 // protein localization to chromosome // inferred by curator /// 0034502 // protein localization to chromosome // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0010370 // perinucleolar chromocenter // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay 220053_at NM_020634 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020634.1 /DEF=Homo sapiens growth differentiation factor 3 (GDF3), mRNA. /FEA=mRNA /GEN=GDF3 /PROD=growth differentiation factor 3 precursor /DB_XREF=gi:10190669 /UG=Hs.86232 growth differentiation factor 3 /FL=gb:NM_020634.1 gb:AF263538.1 NM_020634 growth differentiation factor 3 GDF3 9573 NM_020634 0001501 // skeletal system development // inferred from mutant phenotype /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0010453 // regulation of cell fate commitment // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030903 // notochord development // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0045605 // negative regulation of epidermal cell differentiation // inferred from direct assay /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 220054_at NM_016584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016584.1 /DEF=Homo sapiens SGRF protein, Interleukin 23 p19 subunit (SGRF), mRNA. /FEA=mRNA /GEN=SGRF /PROD=SGRF protein, Interleukin 23 p19 subunit /DB_XREF=gi:7706701 /UG=Hs.98309 SGRF protein, Interleukin 23 p19 subunit /FL=gb:AF301620.1 gb:AB030000.1 gb:NM_016584.1 NM_016584 interleukin 23, alpha subunit p19 IL23A 51561 NM_016584 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from direct assay /// 0002827 // positive regulation of T-helper 1 type immune response // inferred from sequence or structural similarity /// 0002827 // positive regulation of T-helper 1 type immune response // non-traceable author statement /// 0002827 // positive regulation of T-helper 1 type immune response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0032693 // negative regulation of interleukin-10 production // inferred from mutant phenotype /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // traceable author statement /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // traceable author statement /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred by curator /// 0032819 // positive regulation of natural killer cell proliferation // inferred from direct assay /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // traceable author statement /// 0042510 // regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042520 // positive regulation of tyrosine phosphorylation of Stat4 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043382 // positive regulation of memory T cell differentiation // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay /// 0051135 // positive regulation of NK T cell activation // inferred by curator /// 0051135 // positive regulation of NK T cell activation // inferred from direct assay /// 0051142 // positive regulation of NK T cell proliferation // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000330 // positive regulation of T-helper 17 cell lineage commitment // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070743 // interleukin-23 complex // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045519 // interleukin-23 receptor binding // inferred from direct assay 220055_at NM_020653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020653.1 /DEF=Homo sapiens zinc finger protein ZNF287 (ZNF287), mRNA. /FEA=mRNA /GEN=ZNF287 /PROD=zinc finger protein ZNF287 /DB_XREF=gi:10190687 /UG=Hs.99724 zinc finger protein ZNF287 /FL=gb:NM_020653.1 gb:AF217227.1 NM_020653 zinc finger protein 287 ZNF287 57336 NM_020653 /// XM_005256743 /// XM_006721561 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // /// 0006366 // transcription from RNA polymerase II promoter // /// 0014003 // oligodendrocyte development // /// 0042035 // regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220056_at NM_021258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021258.1 /DEF=Homo sapiens interleukin 22 receptor (IL22R), mRNA. /FEA=mRNA /GEN=IL22R /PROD=interleukin 22 receptor /DB_XREF=gi:10864066 /UG=Hs.110915 interleukin 22 receptor /FL=gb:AF286095.1 gb:NM_021258.1 NM_021258 interleukin 22 receptor, alpha 1 IL22RA1 58985 NM_021258 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004904 // interferon receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042015 // interleukin-20 binding // inferred from electronic annotation 220057_at NM_020411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020411.1 /DEF=Homo sapiens XAGE-1 protein (XAGE-1), mRNA. /FEA=mRNA /GEN=XAGE-1 /PROD=XAGE-1 protein /DB_XREF=gi:9966898 /UG=Hs.112208 XAGE-1 protein /FL=gb:AF251237.1 gb:NM_020411.1 NM_020411 X antigen family, member 1B /// X antigen family, member 1E XAGE1B /// XAGE1E 653067 /// 653220 NM_001097591 /// NM_001097592 /// NM_001097593 /// NM_001097594 /// NM_001097595 /// NM_001097596 /// NM_001097597 /// NM_001097598 /// NM_001097602 /// NM_001097603 /// NM_001097604 /// NM_001097605 /// NM_020411 /// NM_133430 /// NM_133431 /// NR_033251 /// NR_033254 /// NR_033257 /// XM_006724595 /// XM_006724596 /// XM_006724597 /// XM_006724598 /// XM_006726846 220058_at NM_024052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024052.1 /DEF=Homo sapiens hypothetical protein MGC3048 (MGC3048), mRNA. /FEA=mRNA /GEN=MGC3048 /PROD=hypothetical protein MGC3048 /DB_XREF=gi:13129019 /UG=Hs.115437 hypothetical protein MGC3048 /FL=gb:BC000636.1 gb:NM_024052.1 NM_024052 GID complex subunit 4 GID4 79018 NM_024052 /// XM_005256799 /// XM_005256800 220059_at NM_012108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012108.1 /DEF=Homo sapiens BCR downstream signaling 1 (BRDG1), mRNA. /FEA=mRNA /GEN=BRDG1 /PROD=BCR downstream signaling 1 /DB_XREF=gi:6912271 /UG=Hs.121128 BCR downstream signaling 1 /FL=gb:AB023483.1 gb:NM_012108.1 NM_012108 signal transducing adaptor family member 1 STAP1 26228 NM_012108 /// XM_005265675 /// XM_006714175 /// XM_006714176 /// XR_427541 0006886 // intracellular protein transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 220060_s_at NM_017915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017915.1 /DEF=Homo sapiens hypothetical protein FLJ20641 (FLJ20641), mRNA. /FEA=mRNA /GEN=FLJ20641 /PROD=hypothetical protein FLJ20641 /DB_XREF=gi:8923595 /UG=Hs.121553 hypothetical protein FLJ20641 /FL=gb:NM_017915.1 NM_017915 PARP1 binding protein PARPBP 55010 NM_017915 /// XM_006719470 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 2000042 // negative regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220061_at NM_017888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017888.1 /DEF=Homo sapiens hypothetical protein FLJ20581 (FLJ20581), mRNA. /FEA=mRNA /GEN=FLJ20581 /PROD=hypothetical protein FLJ20581 /DB_XREF=gi:8923542 /UG=Hs.122939 hypothetical protein FLJ20581 /FL=gb:NM_017888.1 NM_017888 acyl-CoA synthetase medium-chain family member 5 ACSM5 54988 NM_017888 /// XM_006721055 /// XM_006721056 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 220062_s_at NM_016249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016249.1 /DEF=Homo sapiens melanoma antigen, family E, 1, cancertestis specific (MAGEE1), mRNA. /FEA=mRNA /GEN=MAGEE1 /PROD=melanoma antigen, family E, 1, cancertestisspecific /DB_XREF=gi:7706604 /UG=Hs.123536 melanoma antigen, family E, 1, cancertestis specific /FL=gb:AF196482.1 gb:AF116194.1 gb:AF151378.1 gb:NM_016249.1 NM_016249 melanoma antigen family C, 2 MAGEC2 51438 NM_016249 0044257 // cellular protein catabolic process // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 220063_at NM_024751 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024751.1 /DEF=Homo sapiens hypothetical protein FLJ13273 (FLJ13273), mRNA. /FEA=mRNA /GEN=FLJ13273 /PROD=hypothetical protein FLJ13273 /DB_XREF=gi:13376079 /UG=Hs.126119 hypothetical protein FLJ13273 /FL=gb:NM_024751.1 NM_024751 glutathione S-transferase, C-terminal domain containing GSTCD 79807 NM_001031720 /// NM_024751 /// XM_005263222 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220064_at NM_024753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024753.1 /DEF=Homo sapiens hypothetical protein FLJ11457 (FLJ11457), mRNA. /FEA=mRNA /GEN=FLJ11457 /PROD=hypothetical protein FLJ11457 /DB_XREF=gi:13376083 /UG=Hs.126707 hypothetical protein FLJ11457 /FL=gb:NM_024753.1 NM_024753 uncharacterized LOC100506124 /// tetratricopeptide repeat domain 21B LOC100506124 /// TTC21B 79809 /// 100506124 NM_024753 /// NR_045375 /// XM_006712761 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0061512 // protein localization to cilium // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220065_at NM_022144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022144.1 /DEF=Homo sapiens myodulin protein (LOC64102), mRNA. /FEA=mRNA /GEN=LOC64102 /PROD=myodulin protein /DB_XREF=gi:11545882 /UG=Hs.132957 tenomodulin protein /FL=gb:AF191770.1 gb:NM_022144.1 gb:AF234259.1 gb:AB055421.1 NM_022144 tenomodulin TNMD 64102 NM_022144 /// XM_005262175 /// XM_005262176 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0035990 // tendon cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008061 // chitin binding // inferred from electronic annotation 220066_at NM_022162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022162.1 /DEF=Homo sapiens NOD2 protein (NOD2), mRNA. /FEA=mRNA /GEN=NOD2 /PROD=NOD2 protein /DB_XREF=gi:11545911 /UG=Hs.135201 NOD2 protein /FL=gb:AF178930.1 gb:NM_022162.1 NM_022162 nucleotide-binding oligomerization domain containing 2 NOD2 64127 NM_001293557 /// NM_022162 /// XM_005256084 /// XM_006721242 /// XM_006721243 /// XR_429725 /// XR_429726 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002227 // innate immune response in mucosa // inferred from electronic annotation /// 0002253 // activation of immune response // inferred from electronic annotation /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002367 // cytokine production involved in immune response // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from electronic annotation /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002710 // negative regulation of T cell mediated immunity // inferred from electronic annotation /// 0002732 // positive regulation of dendritic cell cytokine production // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002830 // positive regulation of type 2 immune response // inferred from mutant phenotype /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006965 // positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria // inferred from electronic annotation /// 0007254 // JNK cascade // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009595 // detection of biotic stimulus // traceable author statement /// 0016045 // detection of bacterium // inferred from direct assay /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032498 // detection of muramyl dipeptide // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032701 // negative regulation of interleukin-18 production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032731 // positive regulation of interleukin-1 beta production // inferred from mutant phenotype /// 0032733 // positive regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from mutant phenotype /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from electronic annotation /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035419 // activation of MAPK activity involved in innate immune response // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042742 // defense response to bacterium // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0046645 // positive regulation of gamma-delta T cell activation // inferred from sequence or structural similarity /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred by curator /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // traceable author statement /// 0051353 // positive regulation of oxidoreductase activity // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0060585 // positive regulation of prostaglandin-endoperoxide synthase activity // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071225 // cellular response to muramyl dipeptide // inferred from direct assay /// 0071608 // macrophage inflammatory protein-1 alpha production // inferred from electronic annotation /// 0090022 // regulation of neutrophil chemotaxis // inferred from electronic annotation /// 2000110 // negative regulation of macrophage apoptotic process // inferred from sequence or structural similarity /// 2000363 // positive regulation of prostaglandin-E synthase activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032500 // muramyl dipeptide binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay /// 0050700 // CARD domain binding // inferred from physical interaction 220067_at NM_016642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016642.1 /DEF=Homo sapiens beta V spectrin (BSPECV), mRNA. /FEA=mRNA /GEN=BSPECV /PROD=beta V spectrin /DB_XREF=gi:7706189 /UG=Hs.136506 beta V spectrin /FL=gb:AF233523.1 gb:NM_016642.1 NM_016642 spectrin, beta, non-erythrocytic 5 SPTBN5 51332 NM_016642 /// XM_005254438 0007030 // Golgi organization // inferred from mutant phenotype /// 0007041 // lysosomal transport // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008091 // spectrin // non-traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // inferred from direct assay 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay /// 0032029 // myosin tail binding // inferred from direct assay /// 0034452 // dynactin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from direct assay 220068_at NM_013378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013378.1 /DEF=Homo sapiens pre-B lymphocyte gene 3 (VPREB3), mRNA. /FEA=mRNA /GEN=VPREB3 /PROD=pre-B lymphocyte gene 3 /DB_XREF=gi:7019566 /UG=Hs.136713 pre-B lymphocyte gene 3 /FL=gb:AF163825.1 gb:NM_013378.1 NM_013378 pre-B lymphocyte 3 VPREB3 29802 NM_013378 0005783 // endoplasmic reticulum // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 220069_at NM_018943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018943.1 /DEF=Homo sapiens tubulin, alpha-like 2 (TUBAL2), mRNA. /FEA=mRNA /GEN=TUBAL2 /PROD=tubulin, alpha-like 2 /DB_XREF=gi:9507214 /UG=Hs.137400 tubulin, alpha 8 /FL=gb:NM_018943.1 NM_018943 tubulin, alpha 8 TUBA8 51807 NM_001193414 /// NM_018943 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 220070_at NM_024773 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024773.1 /DEF=Homo sapiens hypothetical protein FLJ13798 (FLJ13798), mRNA. /FEA=mRNA /GEN=FLJ13798 /PROD=hypothetical protein FLJ13798 /DB_XREF=gi:13376122 /UG=Hs.141634 hypothetical protein FLJ13798 /FL=gb:NM_024773.1 NM_024773 lysine (K)-specific demethylase 8 KDM8 79831 NM_001145348 /// NM_024773 /// XM_006721092 /// XM_006721093 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay 220071_x_at NM_018097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018097.1 /DEF=Homo sapiens hypothetical protein FLJ10460 (FLJ10460), mRNA. /FEA=mRNA /GEN=FLJ10460 /PROD=hypothetical protein FLJ10460 /DB_XREF=gi:8922429 /UG=Hs.14347 hypothetical protein FLJ10460 /FL=gb:NM_018097.1 NM_018097 HAUS augmin-like complex, subunit 2 HAUS2 55142 NM_001130447 /// NM_018097 /// XM_006720600 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 220072_at NM_024790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024790.1 /DEF=Homo sapiens hypothetical protein FLJ22490 (FLJ22490), mRNA. /FEA=mRNA /GEN=FLJ22490 /PROD=hypothetical protein FLJ22490 /DB_XREF=gi:13376157 /UG=Hs.153746 hypothetical protein FLJ22490 /FL=gb:NM_024790.1 NM_024790 centrosome and spindle pole associated protein 1 CSPP1 79848 NM_001077204 /// NM_001291339 /// NM_024790 /// XM_005251305 /// XM_005251306 /// XM_005251307 /// XM_005251311 /// XM_006716469 /// XM_006716470 /// XM_006716471 /// XM_006716472 /// XM_006716473 /// XM_006716474 /// XM_006716475 /// XM_006716476 /// XM_006716477 /// XM_006716478 /// XM_006716479 /// XM_006716480 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051781 // positive regulation of cell division // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220073_s_at NM_018173 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018173.1 /DEF=Homo sapiens hypothetical protein FLJ10665 (FLJ10665), mRNA. /FEA=mRNA /GEN=FLJ10665 /PROD=hypothetical protein FLJ10665 /DB_XREF=gi:8922580 /UG=Hs.163953 hypothetical protein FLJ10665 /FL=gb:NM_018173.1 NM_018173 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 PLEKHG6 55200 NM_001144856 /// NM_001144857 /// NM_018173 /// XM_005253704 /// XM_005253705 /// XM_005253706 /// XM_006718985 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 220074_at NM_017717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017717.2 /DEF=Homo sapiens mucin and cadherin-like (MUCDHL), mRNA. /FEA=mRNA /GEN=MUCDHL /PROD=MUCDHL-ALT /DB_XREF=gi:12313880 /UG=Hs.165619 mucin and cadherin-like /FL=gb:AF258675.1 gb:NM_017717.2 NM_017717 cadherin-related family member 5 CDHR5 53841 NM_001171968 /// NM_017717 /// NM_021924 /// NM_031264 /// NM_031265 /// XM_005252987 /// XM_005252988 /// XM_005252989 /// XM_005252990 /// XM_006718253 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008013 // beta-catenin binding // inferred from physical interaction 220075_s_at NM_017717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017717.2 /DEF=Homo sapiens mucin and cadherin-like (MUCDHL), mRNA. /FEA=mRNA /GEN=MUCDHL /PROD=MUCDHL-ALT /DB_XREF=gi:12313880 /UG=Hs.165619 mucin and cadherin-like /FL=gb:AF258675.1 gb:NM_017717.2 NM_017717 cadherin-related family member 5 CDHR5 53841 NM_001171968 /// NM_017717 /// NM_021924 /// NM_031264 /// NM_031265 /// XM_005252987 /// XM_005252988 /// XM_005252989 /// XM_005252990 /// XM_006718253 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0008013 // beta-catenin binding // inferred from physical interaction 220076_at NM_019847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019847.2 /DEF=Homo sapiens ankylosis, progressive (mouse) homolog (ANKH), mRNA. /FEA=mRNA /GEN=ANKH /PROD=homolog of mouse Ank /DB_XREF=gi:10947057 /UG=Hs.168640 ankylosis, progressive (mouse) homolog /FL=gb:NM_019847.2 NM_019847 ANKH inorganic pyrophosphate transport regulator ANKH 56172 NM_054027 /// XM_006714483 0001501 // skeletal system development // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0007626 // locomotory behavior // non-traceable author statement /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0030500 // regulation of bone mineralization // traceable author statement /// 0030505 // inorganic diphosphate transport // inferred from direct assay /// 0030505 // inorganic diphosphate transport // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019867 // outer membrane // traceable author statement 0005315 // inorganic phosphate transmembrane transporter activity // inferred from direct assay /// 0015114 // phosphate ion transmembrane transporter activity // inferred from electronic annotation /// 0030504 // inorganic diphosphate transmembrane transporter activity // inferred from direct assay 220077_at NM_024821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024821.1 /DEF=Homo sapiens hypothetical protein FLJ22349 (FLJ22349), mRNA. /FEA=mRNA /GEN=FLJ22349 /PROD=hypothetical protein FLJ22349 /DB_XREF=gi:13376215 /UG=Hs.171012 hypothetical protein FLJ22349 /FL=gb:NM_024821.1 NM_024821 coiled-coil domain containing 134 CCDC134 79879 NM_024821 /// XM_005261748 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 220078_at NM_018391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018391.1 /DEF=Homo sapiens hypothetical protein FLJ11328 (FLJ11328), mRNA. /FEA=mRNA /GEN=FLJ11328 /PROD=hypothetical protein FLJ11328 /DB_XREF=gi:8922996 /UG=Hs.178518 hypothetical protein FLJ11328 /FL=gb:NM_018391.1 NM_018391 ubiquitin specific peptidase 48 USP48 84196 NM_001032730 /// NM_032236 /// XM_005246009 /// XM_005246010 /// XM_006710949 /// XM_006710950 /// XM_006710951 /// XM_006710952 /// XM_006710953 /// XM_006710954 /// XM_006710955 /// XM_006710956 /// XR_426634 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 220079_s_at NM_018391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018391.1 /DEF=Homo sapiens hypothetical protein FLJ11328 (FLJ11328), mRNA. /FEA=mRNA /GEN=FLJ11328 /PROD=hypothetical protein FLJ11328 /DB_XREF=gi:8922996 /UG=Hs.178518 hypothetical protein FLJ11328 /FL=gb:NM_018391.1 NM_018391 ubiquitin specific peptidase 48 USP48 84196 NM_001032730 /// NM_032236 /// XM_005246009 /// XM_005246010 /// XM_006710949 /// XM_006710950 /// XM_006710951 /// XM_006710952 /// XM_006710953 /// XM_006710954 /// XM_006710955 /// XM_006710956 /// XR_426634 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 220080_at NM_018378 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018378.1 /DEF=Homo sapiens hypothetical protein FLJ11278 (FLJ11278), mRNA. /FEA=mRNA /GEN=FLJ11278 /PROD=hypothetical protein FLJ11278 /DB_XREF=gi:8922971 /UG=Hs.187378 hypothetical protein FLJ11278 /FL=gb:NM_018378.1 NM_018378 F-box and leucine-rich repeat protein 8 FBXL8 55336 NM_018378 0005515 // protein binding // inferred from physical interaction 220081_x_at NM_016371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016371.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7), mRNA. /FEA=mRNA /GEN=HSD17B7 /PROD=hydroxysteroid (17-beta) dehydrogenase 7 /DB_XREF=gi:7705420 /UG=Hs.187579 hydroxysteroid (17-beta) dehydrogenase 7 /FL=gb:AF098786.2 gb:NM_016371.1 NM_016371 hydroxysteroid (17-beta) dehydrogenase 7 HSD17B7 51478 NM_016371 /// XM_006711380 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000253 // 3-keto sterol reductase activity // inferred from electronic annotation /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0005148 // prolactin receptor binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 220082_at NM_017726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017726.1 /DEF=Homo sapiens hypothetical protein FLJ20251 (FLJ20251), mRNA. /FEA=mRNA /GEN=FLJ20251 /PROD=hypothetical protein FLJ20251 /DB_XREF=gi:8923225 /UG=Hs.192927 hypothetical protein FLJ20251 /FL=gb:NM_017726.1 NM_017726 protein phosphatase 1, regulatory (inhibitor) subunit 14D PPP1R14D 54866 NM_001130143 /// NM_017726 /// XM_006720585 0035304 // regulation of protein dephosphorylation // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation 220083_x_at NM_016017 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016017.1 /DEF=Homo sapiens CGI-70 protein (LOC51630), mRNA. /FEA=mRNA /GEN=LOC51630 /PROD=CGI-70 protein /DB_XREF=gi:7706307 /UG=Hs.195814 CGI-70 protein /FL=gb:AF151828.1 gb:AF157320.1 gb:NM_016017.1 NM_016017 ubiquitin carboxyl-terminal hydrolase L5 UCHL5 51377 NM_001199261 /// NM_001199262 /// NM_001199263 /// NM_015984 /// NR_037607 /// XM_005245244 /// XM_005245245 /// XM_005245246 /// XM_005245247 /// XM_005245248 /// XM_005245249 /// XM_006711366 /// XM_006711367 /// XM_006711368 /// XM_006711369 /// XM_006711370 /// XM_006711371 /// XM_006711372 /// XM_006711373 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0021670 // lateral ventricle development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from direct assay 220084_at NM_018168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018168.1 /DEF=Homo sapiens hypothetical protein FLJ10650 (FLJ10650), mRNA. /FEA=mRNA /GEN=FLJ10650 /PROD=hypothetical protein FLJ10650 /DB_XREF=gi:8922570 /UG=Hs.200097 hypothetical protein FLJ10650 /FL=gb:NM_018168.1 NM_018168 chromosome 14 open reading frame 105 C14orf105 55195 NM_001283056 /// NM_001283057 /// NM_001283058 /// NM_001283059 /// NM_001283060 /// NM_018168 /// XM_005267806 /// XM_005267807 /// XM_005267809 /// XM_005267810 /// XM_005267811 /// XM_005267813 /// XM_005267814 /// XM_006720188 /// XM_006720189 220085_at NM_018063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018063.1 /DEF=Homo sapiens hypothetical protein FLJ10339 (FLJ10339), mRNA. /FEA=mRNA /GEN=FLJ10339 /PROD=hypothetical protein FLJ10339 /DB_XREF=gi:8922361 /UG=Hs.203963 hypothetical protein FLJ10339 /FL=gb:NM_018063.1 NM_018063 helicase, lymphoid-specific HELLS 3070 NM_001289067 /// NM_001289068 /// NM_001289069 /// NM_001289070 /// NM_001289071 /// NM_001289072 /// NM_001289073 /// NM_001289074 /// NM_001289075 /// NM_018063 /// XM_006717811 0001655 // urogenital system development // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006346 // methylation-dependent chromatin silencing // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from sequence or structural similarity /// 0031508 // centromeric heterochromatin assembly // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046651 // lymphocyte proliferation // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220086_at NM_022466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022466.1 /DEF=Homo sapiens zinc finger transcription factor Pegasus (PEGASUS), mRNA. /FEA=mRNA /GEN=PEGASUS /PROD=zinc finger transcription factor Pegasus /DB_XREF=gi:11968012 /UG=Hs.20631 zinc finger protein, subfamily 1A, 5 (Pegasus) /FL=gb:AF230808.1 gb:NM_022466.1 NM_022466 IKAROS family zinc finger 5 (Pegasus) IKZF5 64376 NM_001271840 /// NR_073475 /// NR_073476 /// NR_073477 /// NR_073478 /// NR_073479 /// XM_006717947 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220087_at NM_017429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017429.1 /DEF=Homo sapiens beta-carotene 15,15-dioxygenase (BCDO), mRNA. /FEA=mRNA /GEN=BCDO /PROD=beta-carotene 15, 15-dioxygenase /DB_XREF=gi:8393364 /UG=Hs.212172 beta-carotene 15,15-dioxygenase /FL=gb:AF294900.1 gb:NM_017429.1 NM_017429 beta-carotene 15,15'-monooxygenase 1 BCMO1 53630 NM_017429 0001523 // retinoid metabolic process // inferred from direct assay /// 0001523 // retinoid metabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0035238 // vitamin A biosynthetic process // non-traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042574 // retinal metabolic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0003834 // beta-carotene 15,15'-monooxygenase activity // inferred from direct assay /// 0003834 // beta-carotene 15,15'-monooxygenase activity // traceable author statement /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220088_at NM_001736 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001736.1 /DEF=Homo sapiens complement component 5 receptor 1 (C5a ligand) (C5R1), mRNA. /FEA=mRNA /GEN=C5R1 /PROD=complement component 5 receptor 1 (C5a ligand) /DB_XREF=gi:4502508 /UG=Hs.2161 complement component 5 receptor 1 (C5a ligand) /FL=gb:M62505.1 gb:NM_001736.1 NM_001736 complement component 5a receptor 1 C5AR1 728 NM_001736 /// XM_005259190 0000187 // activation of MAPK activity // traceable author statement /// 0002430 // complement receptor mediated signaling pathway // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0021534 // cell proliferation in hindbrain // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0038178 // complement component C5a signaling pathway // inferred from direct assay /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay 0001856 // complement component C5a binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004878 // complement component C5a receptor activity // inferred from direct assay /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004942 // anaphylatoxin receptor activity // inferred from electronic annotation /// 0004944 // C5a anaphylatoxin receptor activity // inferred from direct assay /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 220089_at NM_024884 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024884.1 /DEF=Homo sapiens hypothetical protein FLJ12618 (FLJ12618), mRNA. /FEA=mRNA /GEN=FLJ12618 /PROD=hypothetical protein FLJ12618 /DB_XREF=gi:13376330 /UG=Hs.222021 hypothetical protein FLJ12618 /FL=gb:NM_024884.1 NM_024884 L-2-hydroxyglutarate dehydrogenase L2HGDH 79944 NM_024884 /// XM_005268075 /// XM_005268077 0006103 // 2-oxoglutarate metabolic process // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from direct assay /// 0031305 // integral component of mitochondrial inner membrane // non-traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047545 // 2-hydroxyglutarate dehydrogenase activity // inferred from direct assay 220090_at NM_016190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016190.1 /DEF=Homo sapiens chromosome 1 open reading frame 10 (C1ORF10), mRNA. /FEA=mRNA /GEN=C1ORF10 /PROD=tumor-related protein /DB_XREF=gi:7706634 /UG=Hs.242057 chromosome 1 open reading frame 10 /FL=gb:AF077831.1 gb:NM_016190.1 NM_016190 cornulin CRNN 49860 NM_016190 /// XM_006711346 0009408 // response to heat // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 220091_at NM_017585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017585.2 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6), mRNA. /FEA=mRNA /GEN=SLC2A6 /PROD=sugar transporter (SLC2A6 gene) /DB_XREF=gi:9938031 /UG=Hs.244378 solute carrier family 2 (facilitated glucose transporter), member 6 /FL=gb:NM_017585.2 NM_017585 solute carrier family 2 (facilitated glucose transporter), member 6 SLC2A6 11182 NM_001145099 /// NM_017585 /// XR_428513 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 220092_s_at NM_018153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018153.1 /DEF=Homo sapiens hypothetical protein FLJ10601 (FLJ10601), mRNA. /FEA=mRNA /GEN=FLJ10601 /PROD=hypothetical protein FLJ10601 /DB_XREF=gi:8922545 /UG=Hs.257174 hypothetical protein FLJ10601 /FL=gb:NM_018153.1 NM_018153 anthrax toxin receptor 1 ANTXR1 84168 NM_018153 /// NM_032208 /// NM_053034 0007165 // signal transduction // inferred from direct assay /// 0022414 // reproductive process // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 220093_at NM_018153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018153.1 /DEF=Homo sapiens hypothetical protein FLJ10601 (FLJ10601), mRNA. /FEA=mRNA /GEN=FLJ10601 /PROD=hypothetical protein FLJ10601 /DB_XREF=gi:8922545 /UG=Hs.257174 hypothetical protein FLJ10601 /FL=gb:NM_018153.1 NM_018153 anthrax toxin receptor 1 ANTXR1 84168 NM_018153 /// NM_032208 /// NM_053034 0007165 // signal transduction // inferred from direct assay /// 0022414 // reproductive process // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 220094_s_at NM_022102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022102.1 /DEF=Homo sapiens hypothetical protein FLJ20958 (FLJ20958), mRNA. /FEA=mRNA /GEN=FLJ20958 /PROD=hypothetical protein FLJ20958 /DB_XREF=gi:13430855 /UG=Hs.261023 hypothetical protein FLJ20958 /FL=gb:NM_022102.1 NM_022102 mitochondrial calcium uniporter regulator 1 MCUR1 63933 NM_001031713 /// NM_022102 /// XR_241912 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006851 // mitochondrial calcium ion transport // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0070509 // calcium ion import // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220095_at NM_017738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017738.1 /DEF=Homo sapiens hypothetical protein FLJ20276 (FLJ20276), mRNA. /FEA=mRNA /GEN=FLJ20276 /PROD=hypothetical protein FLJ20276 /DB_XREF=gi:8923250 /UG=Hs.270502 hypothetical protein FLJ20276 /FL=gb:NM_017738.1 NM_017738 centlein, centrosomal protein CNTLN 54875 NM_001114395 /// NM_001286984 /// NM_001286985 /// NM_017738 /// XM_005251492 /// XM_006716793 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010457 // centriole-centriole cohesion // inferred from mutant phenotype /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0033365 // protein localization to organelle // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype 220096_at NM_017795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017795.1 /DEF=Homo sapiens hypothetical protein FLJ20378 (FLJ20378), mRNA. /FEA=mRNA /GEN=FLJ20378 /PROD=hypothetical protein FLJ20378 /DB_XREF=gi:8923359 /UG=Hs.274222 hypothetical protein FLJ20378 /FL=gb:NM_017795.1 NM_017795 220097_s_at NM_017728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017728.1 /DEF=Homo sapiens hypothetical protein FLJ20255 (FLJ20255), mRNA. /FEA=mRNA /GEN=FLJ20255 /PROD=hypothetical protein FLJ20255 /DB_XREF=gi:8923229 /UG=Hs.274247 hypothetical protein FLJ20255 /FL=gb:NM_017728.1 NM_017728 transmembrane protein 104 TMEM104 54868 NM_017728 /// XM_005257481 /// XM_006721963 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220098_at NM_017558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017558.1 /DEF=Homo sapiens hypothetical protein DKFZp434L0850 (DKFZp434L0850), mRNA. /FEA=mRNA /GEN=DKFZp434L0850 /PROD=hypothetical protein DKFZp434L0850 /DB_XREF=gi:13430851 /UG=Hs.274322 hypothetical protein DKFZp434L0850 /FL=gb:NM_017558.1 NM_017558 HYDIN, axonemal central pair apparatus protein /// HYDIN2, axonemal central pair apparatus protein (pseudogene) /// hydrocephalus-inducing protein homolog HYDIN /// HYDIN2 /// LOC101930373 54768 /// 100288805 /// 101930373 NM_001198542 /// NM_001198543 /// NM_001270974 /// NM_017558 /// NM_032821 /// NR_049745 /// NR_103556 /// XM_005276093 /// XM_006721206 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 220099_s_at NM_016007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016007.1 /DEF=Homo sapiens CGI-59 protein (LOC51625), mRNA. /FEA=mRNA /GEN=LOC51625 /PROD=CGI-59 protein /DB_XREF=gi:7706297 /UG=Hs.279867 CGI-59 protein /FL=gb:AF151817.1 gb:NM_016007.1 NM_016007 C7orf55-LUC7L2 readthrough /// LUC7-like 2 (S. cerevisiae) C7orf55-LUC7L2 /// LUC7L2 51631 /// 100996928 NM_001244584 /// NM_001244585 /// NM_001270643 /// NM_016019 0006376 // mRNA splice site selection // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 220100_at NM_018484 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018484.1 /DEF=Homo sapiens hOAT4 (LOC55867), mRNA. /FEA=mRNA /GEN=LOC55867 /PROD=hOAT4 /DB_XREF=gi:8923869 /UG=Hs.283078 hOAT4 /FL=gb:AB026116.1 gb:NM_018484.1 NM_018484 solute carrier family 22 (organic anion/urate transporter), member 11 SLC22A11 55867 NM_018484 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from direct assay /// 0046415 // urate metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005452 // inorganic anion exchanger activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 220101_x_at NM_018628 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018628.1 /DEF=Homo sapiens hypothetical protein PRO2472 (PRO2472), mRNA. /FEA=mRNA /GEN=PRO2472 /PROD=hypothetical protein PRO2472 /DB_XREF=gi:8924169 /UG=Hs.283666 hypothetical protein PRO2472 /FL=gb:AF116704.1 gb:NM_018628.1 NM_018628 220102_at NM_023067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023067.1 /DEF=Homo sapiens forkhead transcription factor FOXL2 (BPES), mRNA. /FEA=mRNA /GEN=BPES /PROD=forkhead transcription factor FOXL2 /DB_XREF=gi:12751476 /UG=Hs.289292 forkhead box L2 /FL=gb:AF301906.1 gb:NM_023067.1 NM_023067 forkhead box L2 FOXL2 668 NM_023067 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0002074 // extraocular skeletal muscle development // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007389 // pattern specification process // not recorded /// 0019101 // female somatic sex determination // not recorded /// 0030154 // cell differentiation // non-traceable author statement /// 0042703 // menstruation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded /// 0048048 // embryonic eye morphogenesis // not recorded /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0060014 // granulosa cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0030331 // estrogen receptor binding // not recorded /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0043028 // cysteine-type endopeptidase regulator activity involved in apoptotic process // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220103_s_at NM_016067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016067.1 /DEF=Homo sapiens CGI-134 protein (LOC51023), mRNA. /FEA=mRNA /GEN=LOC51023 /PROD=CGI-134 protein /DB_XREF=gi:7705629 /UG=Hs.3385 CGI-134 protein /FL=gb:NM_016067.1 NM_016067 mitochondrial ribosomal protein S18C MRPS18C 51023 NM_016067 /// XM_005263043 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 220104_at NM_020119 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020119.1 /DEF=Homo sapiens hypothetical protein FLB6421 (FLB6421), mRNA. /FEA=mRNA /GEN=FLB6421 /PROD=hypothetical protein FLB6421 /DB_XREF=gi:9910221 /UG=Hs.35254 hypothetical protein FLB6421 /FL=gb:NM_020119.1 NM_020119 zinc finger CCCH-type, antiviral 1 ZC3HAV1 56829 NM_020119 /// NM_024625 /// XM_005250501 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0061014 // positive regulation of mRNA catabolic process // inferred from direct assay /// 0071360 // cellular response to exogenous dsRNA // inferred from electronic annotation /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220105_at NM_014433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014433.1 /DEF=Homo sapiens rhabdoid tumor deletion region protein 1 (RTDR1), mRNA. /FEA=mRNA /GEN=RTDR1 /PROD=rhabdoid tumor deletion region protein 1 /DB_XREF=gi:7657529 /UG=Hs.35984 rhabdoid tumor deletion region protein 1 /FL=gb:AF133587.1 gb:NM_014433.1 NM_014433 rhabdoid tumor deletion region gene 1 RTDR1 27156 NM_014433 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220106_at NM_013389 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013389.1 /DEF=Homo sapiens NPC1 (Niemann-Pick disease, type C1, gene)-like 1 (NPC1L1), mRNA. /FEA=mRNA /GEN=NPC1L1 /PROD=NPC1 (Niemann-Pick disease, type C1, gene)-like1 /DB_XREF=gi:7019468 /UG=Hs.47701 NPC1 (Niemann-Pick disease, type C1, gene)-like 1 /FL=gb:AF192522.1 gb:NM_013389.1 NM_013389 NPC1-like 1 NPC1L1 29881 NM_001101648 /// NM_013389 /// XM_006715709 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0015918 // sterol transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0031489 // myosin V binding // inferred from physical interaction 220107_s_at NM_024643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024643.1 /DEF=Homo sapiens hypothetical protein FLJ23093 (FLJ23093), mRNA. /FEA=mRNA /GEN=FLJ23093 /PROD=hypothetical protein FLJ23093 /DB_XREF=gi:13375882 /UG=Hs.48642 hypothetical protein FLJ23093 /FL=gb:NM_024643.1 NM_024643 zinc finger, C2HC-type containing 1C ZC2HC1C 79696 NM_001042430 /// NM_024643 /// NR_110315 /// XM_005268062 /// XM_005268063 /// XM_006720255 0046872 // metal ion binding // inferred from electronic annotation 220108_at NM_004297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004297.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha 14 (GNA14), mRNA. /FEA=mRNA /GEN=GNA14 /PROD=guanine nucleotide binding protein (G protein),alpha 14 /DB_XREF=gi:4758443 /UG=Hs.50612 guanine nucleotide binding protein (G protein), alpha 14 /FL=gb:AF105201.1 gb:NM_004297.1 NM_004297 guanine nucleotide binding protein (G protein), alpha 14 GNA14 9630 NM_004297 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220109_at NM_014111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014111.1 /DEF=Homo sapiens PRO2086 protein (PRO2086), mRNA. /FEA=mRNA /GEN=PRO2086 /PROD=PRO2086 protein /DB_XREF=gi:7662634 /UG=Hs.60082 PRO2086 protein /FL=gb:AF118093.1 gb:NM_014111.1 NM_014111 transferrin TF 7018 NM_001063 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030120 // vesicle coat // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097433 // dense body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220110_s_at NM_022052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022052.1 /DEF=Homo sapiens nuclear RNA export factor 3 (NXF3), mRNA. /FEA=mRNA /GEN=NXF3 /PROD=nuclear RNA export factor 3 /DB_XREF=gi:11545756 /UG=Hs.60386 nuclear RNA export factor 3 /FL=gb:NM_022052.1 NM_022052 nuclear RNA export factor 3 NXF3 56000 NM_022052 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220111_s_at NM_020373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020373.1 /DEF=Homo sapiens chromosome 12 open reading frame 3 (C12ORF3), mRNA. /FEA=mRNA /GEN=C12ORF3 /PROD=chromosome 12 open reading frame 3 /DB_XREF=gi:9966844 /UG=Hs.64616 chromosome 12 open reading frame 3 /FL=gb:NM_020373.1 NM_020373 anoctamin 2, calcium activated chloride channel ANO2 57101 NM_001278596 /// NM_001278597 /// NM_020373 /// XM_006718988 /// XM_006718989 /// XM_006718990 /// XM_006718991 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation 0005229 // intracellular calcium activated chloride channel activity // inferred from direct assay /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220112_at NM_024669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024669.1 /DEF=Homo sapiens hypothetical protein FLJ11795 (FLJ11795), mRNA. /FEA=mRNA /GEN=FLJ11795 /PROD=hypothetical protein FLJ11795 /DB_XREF=gi:13375927 /UG=Hs.84560 hypothetical protein FLJ11795 /FL=gb:NM_024669.1 NM_024669 ankyrin repeat domain 55 ANKRD55 79722 NM_001039935 /// NM_024669 /// XM_005248599 /// XM_006714691 0005515 // protein binding // inferred from electronic annotation 220113_x_at NM_019014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019014.1 /DEF=Homo sapiens similar to DNA-directed RNA polymerase I (135 kDa) (FLJ10816), mRNA. /FEA=mRNA /GEN=FLJ10816 /PROD=similar to DNA-directed RNA polymerase I (135kDa) /DB_XREF=gi:9506618 /UG=Hs.86337 similar to DNA-directed RNA polymerase I (135 kDa) /FL=gb:NM_019014.1 NM_019014 polymerase (RNA) I polypeptide B, 128kDa POLR1B 84172 NM_001137604 /// NM_001282772 /// NM_001282774 /// NM_001282776 /// NM_001282777 /// NM_001282779 /// NM_019014 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0009303 // rRNA transcription // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017126 // nucleologenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005737 // cytoplasm // inferred from direct assay 0001054 // RNA polymerase I activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032549 // ribonucleoside binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220114_s_at NM_017564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017564.1 /DEF=Homo sapiens hypothetical protein DKFZp434E0321 (FELL), mRNA. /FEA=mRNA /GEN=FELL /PROD=CD44-like precursor FELL /DB_XREF=gi:12583704 /UG=Hs.8658 hypothetical protein DKFZp434E0321 /FL=gb:NM_017564.1 gb:AF160476.1 NM_017564 stabilin 2 STAB2 55576 NM_017564 /// XM_006719476 /// XR_429107 0001525 // angiogenesis // non-traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0042742 // defense response to bacterium // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from sequence or structural similarity /// 0015035 // protein disulfide oxidoreductase activity // non-traceable author statement /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay 220115_s_at NM_006727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006727.1 /DEF=Homo sapiens cadherin 10, type 2 (T2-cadherin) (CDH10), mRNA. /FEA=mRNA /GEN=CDH10 /PROD=cadherin 10, type 2 (T2-cadherin) /DB_XREF=gi:5802995 /UG=Hs.92489 cadherin 10, type 2 (T2-cadherin) /FL=gb:AF039747.1 gb:NM_006727.1 NM_006727 cadherin 10, type 2 (T2-cadherin) CDH10 1008 NM_001190450 /// NM_006727 /// XR_427656 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220116_at NM_021614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021614.1 /DEF=Homo sapiens potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 2 (KCNN2), mRNA. /FEA=mRNA /GEN=KCNN2 /PROD=potassium intermediatesmall conductancecalcium-activated channel, subfamily N, member 2 /DB_XREF=gi:11055973 /UG=Hs.98280 potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 2 /FL=gb:AF239613.1 gb:NM_021614.1 NM_021614 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 KCNN2 3781 NM_001278204 /// NM_021614 /// NM_170775 /// NR_103458 /// XM_006714613 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043197 // dendritic spine // not recorded 0005216 // ion channel activity // inferred from electronic annotation /// 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0016286 // small conductance calcium-activated potassium channel activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from physical interaction 220117_at NM_024697 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024697.1 /DEF=Homo sapiens hypothetical protein FLJ22419 (FLJ22419), mRNA. /FEA=mRNA /GEN=FLJ22419 /PROD=hypothetical protein FLJ22419 /DB_XREF=gi:13375980 /UG=Hs.99256 hypothetical protein FLJ22419 /FL=gb:NM_024697.1 NM_024697 zinc finger protein 385D ZNF385D 79750 NM_024697 /// XM_005265485 /// XM_005265486 /// XM_005265487 /// XM_005265488 /// XM_006713336 /// XM_006713337 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220118_at NM_014383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014383.1 /DEF=Homo sapiens testis zinc finger protein (TZFP), mRNA. /FEA=mRNA /GEN=TZFP /PROD=testis zinc finger protein /DB_XREF=gi:7657664 /UG=Hs.99430 testis zinc finger protein /FL=gb:AF130255.1 gb:AF165097.1 gb:NM_014383.1 NM_014383 zinc finger and BTB domain containing 32 ZBTB32 27033 NM_014383 /// XM_005258739 /// XM_006723139 /// XR_430195 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 220119_at NM_022140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022140.1 /DEF=Homo sapiens erythrocyte protein band 4.1-like 4 (EPB41L4), mRNA. /FEA=mRNA /GEN=EPB41L4 /PROD=erythrocyte protein band 4.1-like 4 /DB_XREF=gi:11545876 /UG=Hs.104746 erythrocyte protein band 4.1-like 4 /FL=gb:AB030240.1 gb:NM_022140.1 NM_022140 erythrocyte membrane protein band 4.1 like 4A EPB41L4A 64097 NM_022140 /// XM_005272043 /// XM_006714667 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0008092 // cytoskeletal protein binding // inferred from electronic annotation 220120_s_at NM_022140 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022140.1 /DEF=Homo sapiens erythrocyte protein band 4.1-like 4 (EPB41L4), mRNA. /FEA=mRNA /GEN=EPB41L4 /PROD=erythrocyte protein band 4.1-like 4 /DB_XREF=gi:11545876 /UG=Hs.104746 erythrocyte protein band 4.1-like 4 /FL=gb:AB030240.1 gb:NM_022140.1 NM_022140 erythrocyte membrane protein band 4.1 like 4A EPB41L4A 64097 NM_022140 /// XM_005272043 /// XM_006714667 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0008092 // cytoskeletal protein binding // inferred from electronic annotation 220121_at NM_018148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018148.1 /DEF=Homo sapiens hypothetical protein FLJ10583 (FLJ10583), mRNA. /FEA=mRNA /GEN=FLJ10583 /PROD=hypothetical protein FLJ10583 /DB_XREF=gi:8922537 /UG=Hs.105633 hypothetical protein FLJ10583 /FL=gb:NM_018148.1 NM_018148 lines homolog (Drosophila) LINS 55180 NM_001040614 /// NM_001040615 /// NM_001040616 /// NM_018148 /// NM_181739 /// NM_181740 /// XM_005254941 /// XM_005254943 /// XR_243210 /// XR_429462 /// XR_429463 /// XR_429464 220122_at NM_024717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024717.1 /DEF=Homo sapiens hypothetical protein FLJ22344 (FLJ22344), mRNA. /FEA=mRNA /GEN=FLJ22344 /PROD=hypothetical protein FLJ22344 /DB_XREF=gi:13376020 /UG=Hs.107716 hypothetical protein FLJ22344 /FL=gb:NM_024717.1 NM_024717 multiple C2 domains, transmembrane 1 MCTP1 79772 NM_001002796 /// NM_024717 /// XM_005272082 /// XM_005272083 /// XM_005272084 /// XM_005272085 /// XM_005272086 /// XM_005272087 /// XM_005272088 /// XM_005272089 /// XM_005272090 /// XM_005272091 /// XM_006714692 /// XM_006714693 /// XM_006714694 /// XR_427720 0019722 // calcium-mediated signaling // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay 220123_at NM_025181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025181.1 /DEF=Homo sapiens hypothetical protein FLJ22004 (FLJ22004), mRNA. /FEA=mRNA /GEN=FLJ22004 /PROD=hypothetical protein FLJ22004 /DB_XREF=gi:13376773 /UG=Hs.108812 hypothetical protein FLJ22004 /FL=gb:NM_025181.1 NM_025181 solute carrier family 35, member F5 SLC35F5 80255 NM_025181 /// NR_104470 /// XM_005263799 /// XM_005263800 /// XR_427114 0006810 // transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220124_at NM_022041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022041.1 /DEF=Homo sapiens giant axonal neuropathy (gigaxonin) (GAN), mRNA. /FEA=mRNA /GEN=GAN /PROD=gigaxonin /DB_XREF=gi:11545730 /UG=Hs.112569 giant axonal neuropathy (gigaxonin) /FL=gb:AF291673.1 gb:NM_022041.1 NM_022041 gigaxonin GAN 8139 NM_022041 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005883 // neurofilament // non-traceable author statement /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220125_at NM_012144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012144.1 /DEF=Homo sapiens dynein, axonemal, intermediate polypeptide, 1 (DNAI1), mRNA. /FEA=mRNA /GEN=DNAI1 /PROD=dynein, axonemal, intermediate polypeptide, 1 /DB_XREF=gi:6912337 /UG=Hs.112667 dynein, axonemal, intermediate polypeptide, 1 /FL=gb:AF091619.1 gb:NM_012144.1 NM_012144 dynein, axonemal, intermediate chain 1 DNAI1 27019 NM_001281428 /// NM_012144 /// XM_006716755 /// XM_006716756 /// XM_006716757 /// XM_006716758 0003351 // epithelial cilium movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220126_at NM_013270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013270.1 /DEF=Homo sapiens testes-specific protease 50 (TSP50), mRNA. /FEA=mRNA /GEN=TSP50 /PROD=testes-specific protease 50 /DB_XREF=gi:7019562 /UG=Hs.120365 testes-specific protease 50 /FL=gb:AF100707.1 gb:NM_013270.1 NM_013270 protease, serine, 50 PRSS50 29122 NM_013270 0006508 // proteolysis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220127_s_at NM_017703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017703.1 /DEF=Homo sapiens hypothetical protein FLJ20188 (FLJ20188), mRNA. /FEA=mRNA /GEN=FLJ20188 /PROD=hypothetical protein FLJ20188 /DB_XREF=gi:8923178 /UG=Hs.12439 hypothetical protein FLJ20188 /FL=gb:NM_017703.1 NM_017703 F-box and leucine-rich repeat protein 12 FBXL12 54850 NM_017703 /// XM_005259964 /// XM_005259965 /// XM_005259966 /// XM_006722782 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220128_s_at NM_024759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024759.1 /DEF=Homo sapiens hypothetical protein FLJ13955 (FLJ13955), mRNA. /FEA=mRNA /GEN=FLJ13955 /PROD=hypothetical protein FLJ13955 /DB_XREF=gi:13376096 /UG=Hs.127331 hypothetical protein FLJ13955 /FL=gb:NM_024759.1 NM_024759 NIPA-like domain containing 2 NIPAL2 79815 NM_024759 /// XM_005251069 /// XM_005251070 /// XM_005251071 0015693 // magnesium ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from electronic annotation 220129_at NM_017826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017826.1 /DEF=Homo sapiens hypothetical protein FLJ20449 (FLJ20449), mRNA. /FEA=mRNA /GEN=FLJ20449 /PROD=hypothetical protein FLJ20449 /DB_XREF=gi:8923418 /UG=Hs.130546 hypothetical protein FLJ20449 /FL=gb:NM_017826.1 NM_017826 CCDC169-SOHLH2 readthrough /// spermatogenesis and oogenesis specific basic helix-loop-helix 2 CCDC169-SOHLH2 /// SOHLH2 54937 /// 100526761 NM_001198910 /// NM_001282147 /// NM_017826 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220130_x_at NM_019839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019839.1 /DEF=Homo sapiens seven transmembrane receptor BLTR2; leukotriene B4 receptor BLT2 (BLTR2), mRNA. /FEA=mRNA /GEN=BLTR2 /PROD=seven transmembrane receptor BLTR2; leukotrieneB4 receptor BLT2 /DB_XREF=gi:9789896 /UG=Hs.130685 seven transmembrane receptor BLTR2; leukotriene B4 receptor BLT2 /FL=gb:AF308571.1 gb:AF277230.1 gb:AB044402.1 gb:AB029892.1 gb:NM_019839.1 NM_019839 leukotriene B4 receptor 2 LTB4R2 56413 NM_001164692 /// NM_001164693 /// NM_019839 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // /// 0051546 // keratinocyte migration // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005811 // lipid particle // /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001632 // leukotriene B4 receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 220131_at NM_022006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022006.1 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 7 (FXYD7), mRNA. /FEA=mRNA /GEN=FXYD7 /PROD=FXYD domain-containing ion transport regulator7 /DB_XREF=gi:11612658 /UG=Hs.134729 FXYD domain-containing ion transport regulator 7 /FL=gb:NM_022006.1 NM_022006 FXYD domain containing ion transport regulator 7 FXYD7 53822 NM_022006 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043269 // regulation of ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 220132_s_at NM_013269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013269.1 /DEF=Homo sapiens lectin-like NK cell receptor (LLT1), mRNA. /FEA=mRNA /GEN=LLT1 /PROD=lectin-like NK cell receptor /DB_XREF=gi:7019446 /UG=Hs.136748 lectin-like NK cell receptor /FL=gb:AF133299.1 gb:NM_013269.1 gb:AF285087.1 NM_013269 C-type lectin domain family 2, member D CLEC2D 29121 NM_001004419 /// NM_001004420 /// NM_001197317 /// NM_001197318 /// NM_001197319 /// NM_013269 /// NR_036693 0007166 // cell surface receptor signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 220133_at NM_017855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017855.1 /DEF=Homo sapiens hypothetical protein FLJ20513 (FLJ20513), mRNA. /FEA=mRNA /GEN=FLJ20513 /PROD=hypothetical protein FLJ20513 /DB_XREF=gi:8923478 /UG=Hs.143811 hypothetical protein FLJ20513 /FL=gb:NM_017855.1 NM_017855 odontogenic, ameloblast asssociated ODAM 54959 NM_017855 /// XM_005265698 /// XM_006714245 0031214 // biomineral tissue development // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043205 // fibril // inferred from direct assay 220134_x_at NM_018166 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018166.1 /DEF=Homo sapiens hypothetical protein FLJ10647 (FLJ10647), mRNA. /FEA=mRNA /GEN=FLJ10647 /PROD=hypothetical protein FLJ10647 /DB_XREF=gi:8922566 /UG=Hs.144391 hypothetical protein FLJ10647 /FL=gb:NM_018166.1 NM_018166 eva-1 homolog B (C. elegans) EVA1B 55194 NM_018166 /// XM_005270998 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220135_s_at NM_014270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014270.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (SLC7A9), mRNA. /FEA=mRNA /GEN=SLC7A9 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 9 /DB_XREF=gi:7657590 /UG=Hs.145550 solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 /FL=gb:AF141289.1 gb:NM_014270.1 NM_014270 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 SLC7A9 11136 NM_001126335 /// NM_001243036 /// NM_014270 /// XM_005258468 /// XM_006722992 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015811 // L-cystine transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015171 // amino acid transmembrane transporter activity // traceable author statement /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015184 // L-cystine transmembrane transporter activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 220136_s_at NM_005209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005209.1 /DEF=Homo sapiens crystallin, beta A2 (CRYBA2), mRNA. /FEA=mRNA /GEN=CRYBA2 /PROD=crystallin, beta A2 /DB_XREF=gi:7019356 /UG=Hs.146549 crystallin, beta A2 /FL=gb:AF166331.1 gb:NM_005209.1 NM_005209 crystallin, beta A2 CRYBA2 1412 NM_057093 /// NM_057094 0002088 // lens development in camera-type eye // inferred from electronic annotation 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 220137_at NM_019086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019086.1 /DEF=Homo sapiens hypothetical protein FLJ20674 (FLJ20674), mRNA. /FEA=mRNA /GEN=FLJ20674 /PROD=hypothetical protein FLJ20674 /DB_XREF=gi:9506690 /UG=Hs.152519 hypothetical protein FLJ20674 /FL=gb:NM_019086.1 NM_019086 uncharacterized LOC101928274 /// V-set and immunoglobulin domain containing 10 LOC101928274 /// VSIG10 54621 /// 101928274 NM_019086 /// XM_005253908 /// XM_006719467 /// XM_006719468 /// XR_243018 /// XR_424416 /// XR_429192 /// XR_432889 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220138_at NM_004821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004821.1 /DEF=Homo sapiens heart and neural crest derivatives expressed 1 (HAND1), mRNA. /FEA=mRNA /GEN=HAND1 /PROD=basic helix-loop-helix transcription factorHAND1 /DB_XREF=gi:4758505 /UG=Hs.152531 heart and neural crest derivatives expressed 1 /FL=gb:AF061756.1 gb:NM_004821.1 NM_004821 heart and neural crest derivatives expressed 1 HAND1 9421 NM_004821 /// XM_005268531 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001824 // blastocyst development // inferred from expression pattern /// 0001829 // trophectodermal cell differentiation // inferred from expression pattern /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003144 // embryonic heart tube formation // inferred from electronic annotation /// 0003218 // cardiac left ventricle formation // inferred from mutant phenotype /// 0003219 // cardiac right ventricle formation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060411 // cardiac septum morphogenesis // inferred from mutant phenotype /// 0060485 // mesenchyme development // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220139_at NM_013369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013369.1 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L), mRNA. /FEA=mRNA /GEN=DNMT3L /PROD=DNA (cytosine-5-)-methyltransferase 3-like /DB_XREF=gi:7019366 /UG=Hs.157237 DNA (cytosine-5-)-methyltransferase 3-like /FL=gb:BC002560.1 gb:AF194032.1 gb:NM_013369.1 NM_013369 DNA (cytosine-5-)-methyltransferase 3-like DNMT3L 29947 NM_013369 /// NM_175867 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006306 // DNA methylation // non-traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // non-traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0060718 // chorionic trophoblast cell differentiation // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220140_s_at NM_013323 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013323.1 /DEF=Homo sapiens sorting nexin 11 (SNX11), mRNA. /FEA=mRNA /GEN=SNX11 /PROD=sorting nexin 11 /DB_XREF=gi:7019538 /UG=Hs.15827 sorting nexin 11 /FL=gb:AF121861.1 gb:NM_013323.1 NM_013323 sorting nexin 11 SNX11 29916 NM_013323 /// NM_152244 /// XM_005257260 /// XM_005257261 /// XM_005257262 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 1901981 // phosphatidylinositol phosphate binding // inferred from direct assay 220141_at NM_024806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024806.1 /DEF=Homo sapiens hypothetical protein FLJ23554 (FLJ23554), mRNA. /FEA=mRNA /GEN=FLJ23554 /PROD=hypothetical protein FLJ23554 /DB_XREF=gi:13376186 /UG=Hs.164705 hypothetical protein FLJ23554 /FL=gb:NM_024806.1 NM_024806 chromosome 11 open reading frame 63 C11orf63 79864 NM_024806 /// NM_199124 /// XM_005271679 /// XM_005271680 /// XM_005271681 /// XM_006718915 /// XR_428981 220142_at NM_021817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021817.1 /DEF=Homo sapiens brain link protein-1 (BRAL1), mRNA. /FEA=mRNA /GEN=BRAL1 /PROD=brain link protein-1 /DB_XREF=gi:11141886 /UG=Hs.167257 brain link protein-1 /FL=gb:AB049054.1 gb:NM_021817.1 NM_021817 hyaluronan and proteoglycan link protein 2 HAPLN2 60484 NM_021817 /// XM_005245415 /// XM_006711481 /// XM_006711482 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation 220143_x_at NM_018032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018032.1 /DEF=Homo sapiens LUC7 (S. cerevisiae)-like (LUC7L), mRNA. /FEA=mRNA /GEN=LUC7L /PROD=LUC7 (S. cerevisiae)-like /DB_XREF=gi:8922296 /UG=Hs.16803 LUC7 (S. cerevisiae)-like /FL=gb:NM_018032.1 NM_018032 LUC7-like (S. cerevisiae) LUC7L 55692 NM_018032 /// NM_201412 /// XM_005255426 /// XM_005255427 /// XM_005255428 /// XM_005255429 /// XM_006720903 /// XM_006720904 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from electronic annotation 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0050733 // RS domain binding // inferred from electronic annotation 220144_s_at NM_022096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022096.1 /DEF=Homo sapiens hypothetical protein FLJ21669 (FLJ21669), mRNA. /FEA=mRNA /GEN=FLJ21669 /PROD=hypothetical protein FLJ21669 /DB_XREF=gi:11545808 /UG=Hs.174644 hypothetical protein FLJ21669 /FL=gb:NM_022096.1 NM_022096 ankyrin repeat and EF-hand domain containing 1 ANKEF1 63926 NM_022096 /// NM_198798 /// XM_005260792 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220145_at NM_024826 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024826.1 /DEF=Homo sapiens hypothetical protein FLJ21159 (FLJ21159), mRNA. /FEA=mRNA /GEN=FLJ21159 /PROD=hypothetical protein FLJ21159 /DB_XREF=gi:13376225 /UG=Hs.175982 hypothetical protein FLJ21159 /FL=gb:NM_024826.1 NM_024826 microtubule-associated protein 9 MAP9 79884 NM_001039580 /// XM_006714306 /// XM_006714307 /// XM_006714308 0000910 // cytokinesis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 220146_at NM_016562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016562.1 /DEF=Homo sapiens toll-like receptor 7 (LOC51284), mRNA. /FEA=mRNA /GEN=LOC51284 /PROD=toll-like receptor 7 /DB_XREF=gi:7706092 /UG=Hs.179152 toll-like receptor 7 /FL=gb:AF240467.1 gb:NM_016562.1 gb:AF245702.1 NM_016562 toll-like receptor 7 TLR7 51284 NM_016562 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0034154 // toll-like receptor 7 signaling pathway // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0042221 // response to chemical // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045078 // positive regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045356 // positive regulation of interferon-alpha biosynthetic process // inferred from direct assay /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from direct assay /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from mutant phenotype /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032009 // early phagosome // inferred from sequence or structural similarity /// 0036020 // endolysosome membrane // traceable author statement /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from electronic annotation 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from sequence or structural similarity /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0035197 // siRNA binding // inferred from sequence or structural similarity 220147_s_at NM_021238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021238.1 /DEF=Homo sapiens TERA protein (TERA), mRNA. /FEA=mRNA /GEN=TERA /PROD=TERA protein /DB_XREF=gi:10864048 /UG=Hs.180780 TERA protein /FL=gb:NM_021238.1 gb:BC000024.1 NM_021238 family with sequence similarity 60, member A FAM60A 58516 NM_001135811 /// NM_001135812 /// NM_021238 /// XM_005253456 /// XM_005253457 /// XM_005253458 /// XM_006725149 /// XM_006725150 /// XM_006725151 0030336 // negative regulation of cell migration // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016580 // Sin3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220148_at NM_022568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022568.1 /DEF=Homo sapiens aldehyde dehydrogenase 12 (ALDH12), mRNA. /FEA=mRNA /GEN=ALDH12 /PROD=aldehyde dehydrogenase 12 /DB_XREF=gi:12007647 /UG=Hs.18443 aldehyde dehydrogenase 8 family, member A1 /FL=gb:AF303134.1 gb:NM_022568.1 NM_022568 aldehyde dehydrogenase 8 family, member A1 ALDH8A1 64577 NM_001193480 /// NM_022568 /// NM_170771 /// XM_006715551 0008152 // metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042904 // 9-cis-retinoic acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001758 // retinal dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation 220149_at NM_024861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024861.1 /DEF=Homo sapiens hypothetical protein FLJ22671 (FLJ22671), mRNA. /FEA=mRNA /GEN=FLJ22671 /PROD=hypothetical protein FLJ22671 /DB_XREF=gi:13376289 /UG=Hs.193745 hypothetical protein FLJ22671 /FL=gb:NM_024861.1 NM_024861 chromosome 2 open reading frame 54 C2orf54 79919 NM_001085437 /// NM_001282921 /// NM_024861 220150_s_at NM_024581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024581.1 /DEF=Homo sapiens hypothetical protein FLJ13942 (FLJ13942), mRNA. /FEA=mRNA /GEN=FLJ13942 /PROD=hypothetical protein FLJ13942 /DB_XREF=gi:13375761 /UG=Hs.20537 hypothetical protein FLJ13942 /FL=gb:NM_024581.1 NM_024581 family with sequence similarity 184, member A FAM184A 79632 NM_001100411 /// NM_001288576 /// NM_024581 0005615 // extracellular space // inferred from direct assay 220151_at NM_018111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018111.1 /DEF=Homo sapiens hypothetical protein FLJ10490 (FLJ10490), mRNA. /FEA=mRNA /GEN=FLJ10490 /PROD=hypothetical protein FLJ10490 /DB_XREF=gi:8922458 /UG=Hs.221737 hypothetical protein FLJ10490 /FL=gb:NM_018111.1 NM_018111 chromosome 19 open reading frame 73 C19orf73 55150 NM_018111 220152_at NM_024886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024886.1 /DEF=Homo sapiens hypothetical protein FLJ14280 (FLJ14280), mRNA. /FEA=mRNA /GEN=FLJ14280 /PROD=hypothetical protein FLJ14280 /DB_XREF=gi:13376334 /UG=Hs.225084 hypothetical protein FLJ14280 /FL=gb:NM_024886.1 NM_024886 chromosome 10 open reading frame 95 C10orf95 79946 NM_024886 0005515 // protein binding // inferred from physical interaction 220153_at NM_020354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020354.1 /DEF=Homo sapiens lysosomal apyrase-like protein 1 (LALP1), mRNA. /FEA=mRNA /GEN=LALP1 /PROD=lysosomal apyrase-like protein 1 /DB_XREF=gi:9966820 /UG=Hs.22604 lysosomal apyrase-like protein 1 /FL=gb:AF269255.1 gb:NM_020354.1 NM_020354 ectonucleoside triphosphate diphosphohydrolase 7 ENTPD7 57089 NM_020354 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220154_at NM_020388 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020388.1 /DEF=Homo sapiens CATX-15 protein (CATX-15), mRNA. /FEA=mRNA /GEN=CATX-15 /PROD=CATX-15 protein /DB_XREF=gi:9966862 /UG=Hs.229535 CATX-15 protein /FL=gb:AF083131.1 gb:NM_020388.1 NM_020388 dystonin DST 667 NM_001144769 /// NM_001144770 /// NM_001144771 /// NM_001723 /// NM_015548 /// NM_020388 /// NM_183380 /// XM_005249310 /// XM_005249311 /// XM_005249312 /// XM_005249313 /// XM_005249314 /// XM_005249315 /// XM_005249316 /// XM_005249317 /// XM_005249318 /// XM_005249319 /// XM_005249320 /// XM_005249322 /// XM_005249323 /// XM_005249324 /// XM_005249325 /// XM_005249326 /// XM_006715169 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008090 // retrograde axon cargo transport // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0030011 // maintenance of cell polarity // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from expression pattern /// 0045104 // intermediate filament cytoskeleton organization // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // non-traceable author statement /// 0048870 // cell motility // inferred from mutant phenotype 0005604 // basement membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009925 // basal plasma membrane // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0030056 // hemidesmosome // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from direct assay /// 0031673 // H zone // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0060053 // neurofilament cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 220155_s_at NM_023924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023924.1 /DEF=Homo sapiens hypothetical protein FLJ13441 (FLJ13441), mRNA. /FEA=mRNA /GEN=FLJ13441 /PROD=hypothetical protein FLJ13441 /DB_XREF=gi:12965190 /UG=Hs.232146 hypothetical protein FLJ13441 /FL=gb:NM_023924.1 NM_023924 bromodomain containing 9 BRD9 65980 NM_001009877 /// NM_023924 /// NR_027633 /// XM_006714492 /// XM_006714493 /// XM_006714494 /// XR_427662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation 0003676 // nucleic acid binding // non-traceable author statement /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 220156_at NM_024593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024593.1 /DEF=Homo sapiens hypothetical protein FLJ11767 (FLJ11767), mRNA. /FEA=mRNA /GEN=FLJ11767 /PROD=hypothetical protein FLJ11767 /DB_XREF=gi:13375786 /UG=Hs.23245 hypothetical protein FLJ11767 /FL=gb:NM_024593.1 NM_024593 EF-hand calcium binding domain 1 EFCAB1 79645 NM_001142857 /// NM_024593 /// NR_024605 /// XM_005251303 /// XM_005251304 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220157_x_at NM_015899 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015899.1 /DEF=Homo sapiens putative glycolipid transfer protein (LOC51054), mRNA. /FEA=mRNA /GEN=LOC51054 /PROD=putative glycolipid transfer protein /DB_XREF=gi:7705683 /UG=Hs.233495 putative glycolipid transfer protein /FL=gb:AF103731.1 gb:NM_015899.1 NM_015899 pleckstrin homology domain containing, family A member 8 pseudogene 1 PLEKHA8P1 51054 NM_015899 /// NR_037144 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from direct assay /// 0006869 // lipid transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0035621 // ER to Golgi ceramide transport // inferred from direct assay /// 0046836 // glycolipid transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0017089 // glycolipid transporter activity // inferred from electronic annotation /// 0051861 // glycolipid binding // inferred from electronic annotation /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay /// 0097001 // ceramide binding // inferred from direct assay 220158_at NM_020129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020129.1 /DEF=Homo sapiens placental protein 13-like protein (LOC56891), mRNA. /FEA=mRNA /GEN=LOC56891 /PROD=placental protein 13-like protein /DB_XREF=gi:9910347 /UG=Hs.24236 placental protein 13-like protein /FL=gb:AF267852.1 gb:NM_020129.1 NM_020129 lectin, galactoside-binding, soluble, 14 LGALS14 56891 NM_020129 /// NM_203471 0006915 // apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0030246 // carbohydrate binding // inferred from electronic annotation 220159_at NM_024903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024903.1 /DEF=Homo sapiens hypothetical protein FLJ14297 (FLJ14297), mRNA. /FEA=mRNA /GEN=FLJ14297 /PROD=hypothetical protein FLJ14297 /DB_XREF=gi:13435146 /UG=Hs.245043 hypothetical protein FLJ14297 /FL=gb:NM_024903.1 NM_024903 ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene ABCA11P 79963 NM_024903 /// NR_002451 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220160_s_at NM_007059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007059.1 /DEF=Homo sapiens kaptin (actin-binding protein) (KPTN), mRNA. /FEA=mRNA /GEN=KPTN /PROD=kaptin (actin-binding protein) /DB_XREF=gi:5901993 /UG=Hs.25441 kaptin (actin-binding protein) /FL=gb:AF105369.1 gb:NM_007059.1 NM_007059 kaptin (actin binding protein) KPTN 11133 NM_001291296 /// NM_007059 /// NR_111923 /// XM_005258467 0006928 // cellular component movement // traceable author statement /// 0007015 // actin filament organization // traceable author statement /// 0007605 // sensory perception of sound // non-traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 220161_s_at NM_019114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019114.1 /DEF=Homo sapiens EHM2 gene (EHM2), mRNA. /FEA=mRNA /GEN=EHM2 /PROD=EHM2 gene /DB_XREF=gi:9506568 /UG=Hs.267997 EHM2 gene /FL=gb:NM_019114.1 NM_019114 erythrocyte membrane protein band 4.1 like 4B EPB41L4B 54566 NM_018424 /// NM_019114 /// XM_006717144 /// XM_006717145 /// XM_006717146 0031032 // actomyosin structure organization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 220162_s_at NM_022352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022352.1 /DEF=Homo sapiens caspase recruitment domain protein 9 (LOC64170), mRNA. /FEA=mRNA /GEN=LOC64170 /PROD=caspase recruitment domain protein 9 /DB_XREF=gi:11641262 /UG=Hs.271815 caspase recruitment domain protein 9 /FL=gb:NM_022352.1 NM_022352 caspase recruitment domain family, member 9 /// DNL-type zinc finger CARD9 /// DNLZ 64170 /// 728489 NM_001080849 /// NM_052813 /// NM_052814 /// NR_073565 0002376 // immune system process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042534 // regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045076 // regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from electronic annotation /// 0045408 // regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050700 // CARD domain binding // inferred from physical interaction 220163_s_at NM_018411 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018411.1 /DEF=Homo sapiens hairless protein (putative single zinc finger transcription factor protein, responsible for autosomal recessive universal congenital alopecia, HR gene) (HSA277165), mRNA. /FEA=mRNA /GEN=HSA277165 /PROD=hairless protein /DB_XREF=gi:11036651 /UG=Hs.272367 hairless protein (putative single zinc finger transcription factor protein, responsible for autosomal recessive universal congenital alopecia, HR gene) /FL=gb:NM_018411.1 NM_018411 hair growth associated HR 55806 NM_005144 /// NM_018411 /// XM_005273569 /// XM_006716367 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0016604 // nuclear body // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220164_s_at NM_016298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016298.1 /DEF=Homo sapiens muscle disease-related protein (LOC51725), mRNA. /FEA=mRNA /GEN=LOC51725 /PROD=muscle disease-related protein /DB_XREF=gi:7706492 /UG=Hs.272564 muscle disease-related protein /FL=gb:AF204674.1 gb:NM_016298.1 NM_016298 F-box protein 40 FBXO40 51725 NM_016298 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220165_at NM_017759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017759.1 /DEF=Homo sapiens hypothetical protein FLJ20309 (FLJ20309), mRNA. /FEA=mRNA /GEN=FLJ20309 /PROD=hypothetical protein FLJ20309 /DB_XREF=gi:8923290 /UG=Hs.272793 hypothetical protein FLJ20309 /FL=gb:NM_017759.1 NM_017759 INO80 complex subunit D INO80D 54891 NM_017759 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220166_at NM_020348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020348.1 /DEF=Homo sapiens cyclin M1 (CNNM1), mRNA. /FEA=mRNA /GEN=CNNM1 /PROD=cyclin M1 /DB_XREF=gi:9966788 /UG=Hs.274579 cyclin M1 /FL=gb:AF169226.1 gb:NM_020348.1 NM_020348 cyclin M1 CNNM1 26507 NM_020348 /// XM_005269692 /// XM_006717757 /// XM_006717758 /// XM_006717759 /// XR_428704 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0030554 // adenyl nucleotide binding // inferred from electronic annotation 220167_s_at NM_015369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015369.1 /DEF=Homo sapiens TP53TG3 protein (TP53TG3), mRNA. /FEA=mRNA /GEN=TP53TG3 /PROD=TP53TG3 protein /DB_XREF=gi:7662674 /UG=Hs.278513 TP53TG3 protein /FL=gb:AB023508.1 gb:NM_015369.1 NM_015369 TP53 target 3 /// TP53 target 3B /// TP53 target 3C /// TP53 target 3D TP53TG3 /// TP53TG3B /// TP53TG3C /// TP53TG3D 24150 /// 653550 /// 729264 /// 729355 NM_001099687 /// NM_001205259 /// NM_001205260 /// NM_001205265 /// NM_001243722 /// NM_001267813 /// NM_015369 /// NM_016212 /// NR_110886 /// NR_110897 /// NR_110898 /// NR_110910 /// NR_110911 /// NR_110914 /// XM_006721026 /// XM_006721027 /// XM_006721074 /// XM_006721075 /// XM_006721084 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 220168_at NM_018272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018272.1 /DEF=Homo sapiens hypothetical protein FLJ10921 (FLJ10921), mRNA. /FEA=mRNA /GEN=FLJ10921 /PROD=hypothetical protein FLJ10921 /DB_XREF=gi:8922767 /UG=Hs.279012 hypothetical protein FLJ10921 /FL=gb:NM_018272.1 NM_018272 cancer susceptibility candidate 1 CASC1 55259 NM_001082972 /// NM_001082973 /// NM_001204101 /// NM_001204102 /// NM_018272 /// XM_005253406 /// XM_005253407 /// XM_005253408 /// XM_005253409 /// XM_005253410 /// XM_005253411 /// XM_006719100 /// XM_006719101 /// XM_006719102 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0008017 // microtubule binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 220169_at NM_024943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024943.1 /DEF=Homo sapiens hypothetical protein FLJ23235 (FLJ23235), mRNA. /FEA=mRNA /GEN=FLJ23235 /PROD=hypothetical protein FLJ23235 /DB_XREF=gi:13376422 /UG=Hs.283578 hypothetical protein FLJ23235 /FL=gb:NM_024943.1 NM_024943 transmembrane protein 156 TMEM156 80008 NM_024943 /// XM_005262669 /// XM_005262670 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220170_at NM_020482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020482.1 /DEF=Homo sapiens activator of CREM in testis (ACT), mRNA. /FEA=mRNA /GEN=ACT /PROD=activator of CREM in testis /DB_XREF=gi:10047075 /UG=Hs.283689 activator of CREM in testis /FL=gb:NM_020482.1 gb:AF278541.1 NM_020482 four and a half LIM domains 5 FHL5 9457 NM_001170807 /// NM_020482 /// XM_006715613 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220171_x_at NM_018559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018559.1 /DEF=Homo sapiens lipopolysaccharide specific response-7 protein (LSR7), mRNA. /FEA=mRNA /GEN=LSR7 /PROD=lipopolysaccharide specific response-7 protein /DB_XREF=gi:8923916 /UG=Hs.283709 lipopolysaccharide specific response-7 protein /FL=gb:AF145122.1 gb:NM_018559.1 NM_018559 GPALPP motifs containing 1 GPALPP1 55425 NM_018559 /// XM_005266443 /// XM_005266444 220172_at NM_025000 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025000.1 /DEF=Homo sapiens hypothetical protein FLJ13096 (FLJ13096), mRNA. /FEA=mRNA /GEN=FLJ13096 /PROD=hypothetical protein FLJ13096 /DB_XREF=gi:13376510 /UG=Hs.287549 hypothetical protein FLJ13096 /FL=gb:NM_025000.1 NM_025000 DDB1 and CUL4 associated factor 17 DCAF17 80067 NM_001164821 /// NM_025000 /// NR_028482 /// XM_006712766 /// XM_006712767 /// XM_006712768 /// XM_006712769 /// XM_006712770 /// XM_006712771 /// XM_006712772 /// XM_006712773 /// XR_427113 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 220173_at NM_025057 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025057.1 /DEF=Homo sapiens hypothetical protein FLJ23189 (FLJ23189), mRNA. /FEA=mRNA /GEN=FLJ23189 /PROD=hypothetical protein FLJ23189 /DB_XREF=gi:13376590 /UG=Hs.287733 hypothetical protein FLJ23189 /FL=gb:NM_025057.1 NM_025057 coiled-coil domain containing 176 CCDC176 80127 NM_025057 /// XM_005268092 /// XM_005268093 /// XM_005268094 /// XM_005268095 /// XM_005268096 /// XM_005268097 /// XM_005268098 /// XR_245725 0044458 // motile cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 220174_at NM_025061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025061.1 /DEF=Homo sapiens hypothetical protein FLJ23420 (FLJ23420), mRNA. /FEA=mRNA /GEN=FLJ23420 /PROD=hypothetical protein FLJ23420 /DB_XREF=gi:13376596 /UG=Hs.287740 hypothetical protein FLJ23420 /FL=gb:NM_025061.1 NM_025061 leucine rich repeat containing 8 family, member E LRRC8E 80131 NM_001268284 /// NM_001268285 /// NM_025061 /// XM_005272497 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220175_s_at NM_020667 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020667.1 /DEF=Homo sapiens hypothetical protein from clone 1659351 (LOC57397), mRNA. /FEA=mRNA /GEN=LOC57397 /PROD=hypothetical protein from clone 1659351 /DB_XREF=gi:10190707 /UG=Hs.288838 hypothetical protein from clone 1659351 /FL=gb:NM_020667.1 NM_020667 COBW domain containing 1 /// COBW domain containing 2 /// COBW domain containing 3 /// COBW domain containing 5 /// COBW domain containing 6 /// COBW domain containing 7 /// putative COBW domain-containing protein 7-like CBWD1 /// CBWD2 /// CBWD3 /// CBWD5 /// CBWD6 /// CBWD7 /// LOC101060578 55871 /// 150472 /// 220869 /// 445571 /// 644019 /// 728013 /// 101060578 NM_001024916 /// NM_001085457 /// NM_001145355 /// NM_001145356 /// NM_001286835 /// NM_001286836 /// NM_001291821 /// NM_018491 /// NM_172003 /// NM_201453 /// NR_104600 /// XM_001717050 /// XM_005251513 /// XM_005251514 /// XM_005251515 /// XM_005251516 /// XM_005251517 /// XM_005251991 /// XM_005263600 /// XM_005263602 /// XM_005263603 /// XM_005263604 /// XM_005263605 /// XM_005263606 /// XM_005272526 /// XM_005272748 /// XM_005272749 /// XM_005272750 /// XM_005272751 /// XM_005272754 /// XM_005272755 /// XM_005277637 /// XM_005277639 /// XM_005277640 /// XM_005277641 /// XM_006716848 /// XM_006716849 /// XM_006716850 /// XM_006716914 /// XM_006716915 /// XM_006717116 /// XM_006726500 /// XM_006726501 /// XR_244814 /// XR_249193 /// XR_254402 /// XR_427073 /// XR_428424 /// XR_428425 /// XR_428503 /// XR_428504 /// XR_428530 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 220176_at NM_025152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025152.1 /DEF=Homo sapiens hypothetical protein FLJ12660 (FLJ12660), mRNA. /FEA=mRNA /GEN=FLJ12660 /PROD=hypothetical protein FLJ12660 /DB_XREF=gi:13376746 /UG=Hs.288981 hypothetical protein FLJ12660 /FL=gb:NM_025152.1 NM_025152 nucleotide binding protein-like NUBPL 80224 NM_001201573 /// NM_001201574 /// NM_025152 /// NR_120408 /// XM_005268099 /// XM_006720259 /// XM_006720260 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 220177_s_at NM_024022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024022.1 /DEF=Homo sapiens Transmembrane protease, serine 3 (TMPRSS3), mRNA. /FEA=mRNA /GEN=TMPRSS3 /PROD=transmembrane protease, serine 3 /DB_XREF=gi:13173470 /UG=Hs.298241 Transmembrane protease, serine 3 /FL=gb:AB038157.1 gb:NM_024022.1 NM_024022 transmembrane protease, serine 3 TMPRSS3 64699 NM_001256317 /// NM_024022 /// NM_032401 /// NM_032404 /// NM_032405 /// NR_046020 0006508 // proteolysis // non-traceable author statement /// 0006883 // cellular sodium ion homeostasis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay 220178_at NM_021731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021731.1 /DEF=Homo sapiens hypothetical protein PP3501 (PP3501), mRNA. /FEA=mRNA /GEN=PP3501 /PROD=hypothetical protein PP3501 /DB_XREF=gi:11119425 /UG=Hs.301406 hypothetical protein PP3501 /FL=gb:NM_021731.1 NM_021731 major facilitator superfamily domain containing 12 MFSD12 126321 NM_001042680 /// NM_001287529 /// NM_021731 /// NM_174983 /// XM_005259490 /// XM_006722646 /// XM_006722647 0006810 // transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220179_at NM_022357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022357.1 /DEF=Homo sapiens putative metallopeptidase (family M19) (LOC64180), mRNA. /FEA=mRNA /GEN=LOC64180 /PROD=putative metallopeptidase (family M19) /DB_XREF=gi:11641272 /UG=Hs.302028 putative metallopeptidase (family M19) /FL=gb:NM_022357.1 NM_022357 dipeptidase 3 DPEP3 64180 NM_001129758 /// NM_022357 0006508 // proteolysis // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007140 // male meiosis // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220180_at NM_025214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025214.1 /DEF=Homo sapiens CTCL tumor antigen se57-1 (SE57-1), mRNA. /FEA=mRNA /GEN=SE57-1 /PROD=CTCL tumor antigen se57-1 /DB_XREF=gi:13376817 /UG=Hs.30315 CTCL tumor antigen se57-1 /FL=gb:AF273051.1 gb:NM_025214.1 NM_025214 coiled-coil domain containing 68 CCDC68 80323 NM_001143829 /// NM_025214 /// XM_005266772 /// XM_006722552 220181_x_at NM_024055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024055.1 /DEF=Homo sapiens hypothetical protein MGC5499 (MGC5499), mRNA. /FEA=mRNA /GEN=MGC5499 /PROD=hypothetical protein MGC5499 /DB_XREF=gi:13443011 /UG=Hs.306223 hypothetical protein MGC5499 /FL=gb:BC000808.1 gb:NM_024055.1 NM_024055 solute carrier family 30 (zinc transporter), member 5 SLC30A5 64924 NM_001251969 /// NM_022902 /// NM_024055 /// XM_005248569 /// XM_006714672 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006829 // zinc ion transport // inferred from direct assay /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0010043 // response to zinc ion // inferred from direct assay /// 0010155 // regulation of proton transport // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0030667 // secretory granule membrane // traceable author statement 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 220182_at NM_024103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024103.1 /DEF=Homo sapiens hypothetical protein MGC2615 (MGC2615), mRNA. /FEA=mRNA /GEN=MGC2615 /PROD=hypothetical protein MGC2615 /DB_XREF=gi:13430867 /UG=Hs.32246 hypothetical protein MGC2615 /FL=gb:BC001656.1 gb:NM_024103.1 NM_024103 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 SLC25A23 79085 NM_024103 /// XM_006722884 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220183_s_at NM_007083 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007083.1 /DEF=Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 6 (NUDT6), mRNA. /FEA=mRNA /GEN=NUDT6 /PROD=nudix (nucleoside diphosphate linked moietyX)-type motif 6 /DB_XREF=gi:11095442 /UG=Hs.323664 nudix (nucleoside diphosphate linked moiety X)-type motif 6 /FL=gb:NM_007083.1 gb:AF019632.2 NM_007083 nudix (nucleoside diphosphate linked moiety X)-type motif 6 NUDT6 11162 NM_007083 /// NM_198041 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0008083 // growth factor activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 220184_at NM_024865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024865.1 /DEF=Homo sapiens hypothetical protein FLJ12581 (FLJ12581), mRNA. /FEA=mRNA /GEN=FLJ12581 /PROD=hypothetical protein FLJ12581 /DB_XREF=gi:13376297 /UG=Hs.326290 hypothetical protein FLJ12581 /FL=gb:NM_024865.1 NM_024865 Nanog homeobox NANOG 79923 NM_024865 /// XM_005253484 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001710 // mesodermal cell fate commitment // inferred from electronic annotation /// 0001714 // endodermal cell fate specification // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008406 // gonad development // inferred from electronic annotation /// 0009790 // embryo development // inferred from expression pattern /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0017145 // stem cell division // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from expression pattern /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from mutant phenotype /// 0045595 // regulation of cell differentiation // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 220185_at NM_025213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025213.1 /DEF=Homo sapiens spectrin beta 4 (KIAA1642), mRNA. /FEA=mRNA /GEN=KIAA1642 /PROD=spectrin beta 4 /DB_XREF=gi:13435160 /UG=Hs.32706 spectrin beta 4 /FL=gb:AF082075.1 gb:AF311855.1 gb:NM_025213.1 NM_025213 spectrin, beta, non-erythrocytic 4 SPTBN4 57731 NM_020971 /// NM_025213 /// XM_006723306 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0007016 // cytoskeletal anchoring at plasma membrane // traceable author statement /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0007628 // adult walking behavior // inferred from sequence or structural similarity /// 0009566 // fertilization // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022414 // reproductive process // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0033135 // regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045162 // clustering of voltage-gated sodium channels // inferred from sequence or structural similarity /// 0051693 // actin filament capping // inferred from electronic annotation /// 0061337 // cardiac conduction // inferred from sequence or structural similarity /// 0090002 // establishment of protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0008091 // spectrin // inferred from direct assay /// 0008091 // spectrin // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043203 // axon hillock // inferred from sequence or structural similarity /// 0070852 // cell body fiber // inferred from sequence or structural similarity 0003779 // actin binding // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0030506 // ankyrin binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from sequence or structural similarity 220186_s_at NM_017675 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017675.1 /DEF=Homo sapiens hypothetical protein FLJ20124 (FLJ20124), mRNA. /FEA=mRNA /GEN=FLJ20124 /PROD=hypothetical protein FLJ20124 /DB_XREF=gi:8923121 /UG=Hs.4205 hypothetical protein FLJ20124 /FL=gb:NM_017675.1 NM_017675 cadherin-related family member 2 CDHR2 54825 NM_001171976 /// NM_017675 /// XM_006714887 0007155 // cell adhesion // inferred from direct assay /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220187_at NM_024636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024636.1 /DEF=Homo sapiens hypothetical protein FLJ23153 (FLJ23153), mRNA. /FEA=mRNA /GEN=FLJ23153 /PROD=hypothetical protein FLJ23153 /DB_XREF=gi:13375867 /UG=Hs.44208 hypothetical protein FLJ23153 /FL=gb:NM_024636.1 NM_024636 STEAP family member 4 STEAP4 79689 NM_001205315 /// NM_001205316 /// NM_024636 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220188_at NM_020655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020655.1 /DEF=Homo sapiens junctophilin 3 (JPH3), mRNA. /FEA=mRNA /GEN=JPH3 /PROD=junctophilin 3 /DB_XREF=gi:10190691 /UG=Hs.4775 junctophilin 3 /FL=gb:NM_020655.1 gb:AB042636.1 NM_020655 junctophilin 3 JPH3 57338 NM_001271604 /// NM_001271605 /// NM_020655 /// NR_073379 /// XM_006721237 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0035640 // exploration behavior // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060402 // calcium ion transport into cytosol // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030314 // junctional membrane complex // inferred from electronic annotation 0015278 // calcium-release channel activity // inferred from electronic annotation 220189_s_at NM_014275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014275.1 /DEF=Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B (MGAT4B), mRNA. /FEA=mRNA /GEN=MGAT4B /PROD=mannosyl (alpha-1,3-)-glycoproteinbeta-1,4-N-acetylglucosaminyltransferase, isoenzyme B /DB_XREF=gi:7710151 /UG=Hs.4867 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B /FL=gb:AB000624.1 gb:NM_014275.1 NM_014275 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B MGAT4B 11282 NM_014275 /// NM_054013 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006491 // N-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008454 // alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220190_s_at NM_006873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006873.1 /DEF=Homo sapiens stoned BTFIIA-alphabeta-like factor (SALF), mRNA. /FEA=mRNA /GEN=SALF /PROD=stoned BTFIIA-alphabeta-like factor /DB_XREF=gi:5803152 /UG=Hs.54961 stoned BTFIIA-alphabeta-like factor /FL=gb:AF026169.1 gb:NM_006873.1 NM_006873 general transcription factor IIA, 1-like /// STON1-GTF2A1L readthrough GTF2A1L /// STON1-GTF2A1L 11036 /// 286749 NM_001193487 /// NM_001198593 /// NM_001198594 /// NM_006872 /// NM_172196 /// NM_172311 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005672 // transcription factor TFIIA complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220191_at NM_019617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019617.1 /DEF=Homo sapiens CA11 (LOC56287), mRNA. /FEA=mRNA /GEN=LOC56287 /PROD=CA11 /DB_XREF=gi:9665239 /UG=Hs.69319 CA11 /FL=gb:AB039886.1 gb:NM_019617.1 NM_019617 gastrokine 1 GKN1 56287 NM_019617 0007586 // digestion // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 220192_x_at NM_012391 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012391.1 /DEF=Homo sapiens prostate epithelium-specific Ets transcription factor (PDEF), mRNA. /FEA=mRNA /GEN=PDEF /PROD=prostate epithelium-specific Ets transcriptionfactor /DB_XREF=gi:6912579 /UG=Hs.79414 prostate epithelium-specific Ets transcription factor /FL=gb:AF071538.1 gb:AB031549.1 gb:NM_012391.1 NM_012391 SAM pointed domain containing ETS transcription factor SPDEF 25803 NM_001252294 /// NM_012391 /// XM_005248988 /// XM_006715048 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007275 // multicellular organismal development // traceable author statement /// 0010454 // negative regulation of cell fate commitment // inferred from electronic annotation /// 0010455 // positive regulation of cell fate commitment // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220193_at NM_024676 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024676.1 /DEF=Homo sapiens hypothetical protein FLJ22938 (FLJ22938), mRNA. /FEA=mRNA /GEN=FLJ22938 /PROD=hypothetical protein FLJ22938 /DB_XREF=gi:13375941 /UG=Hs.87016 hypothetical protein FLJ22938 /FL=gb:NM_024676.1 NM_024676 SH3 domain containing 21 SH3D21 79729 NM_001162530 /// NM_024676 /// XM_005271204 /// XM_005271205 /// XM_006710901 /// XM_006710902 /// XR_426626 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 220194_at NM_024677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024677.1 /DEF=Homo sapiens hypothetical protein FLJ14001 (FLJ14001), mRNA. /FEA=mRNA /GEN=FLJ14001 /PROD=hypothetical protein FLJ14001 /DB_XREF=gi:13375943 /UG=Hs.87164 hypothetical protein FLJ14001 /FL=gb:NM_024677.1 NM_024677 NOP2/Sun domain family, member 7 NSUN7 79730 NM_024677 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 220195_at NM_018328 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018328.1 /DEF=Homo sapiens hypothetical protein FLJ11113 (FLJ11113), mRNA. /FEA=mRNA /GEN=FLJ11113 /PROD=hypothetical protein FLJ11113 /DB_XREF=gi:8922876 /UG=Hs.94125 hypothetical protein FLJ11113 /FL=gb:NM_018328.1 NM_018328 methyl-CpG binding domain protein 5 MBD5 55777 NM_018328 /// XM_005263711 /// XM_005263712 0007399 // nervous system development // inferred from mutant phenotype /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044708 // single-organism behavior // inferred from mutant phenotype /// 0060399 // positive regulation of growth hormone receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0010369 // chromocenter // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay 220196_at NM_024690 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024690.1 /DEF=Homo sapiens hypothetical protein FLJ14303 (FLJ14303), mRNA. /FEA=mRNA /GEN=FLJ14303 /PROD=hypothetical protein FLJ14303 /DB_XREF=gi:13375965 /UG=Hs.98502 hypothetical protein FLJ14303 /FL=gb:NM_024690.1 NM_024690 mucin 16, cell surface associated MUC16 94025 NM_024690 /// XM_006722941 0007155 // cell adhesion // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220197_at NM_020632 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020632.1 /DEF=Homo sapiens ATPase, H(+)-transporting, lysosomal, noncatalytic accessory protein 1B (ATP6N1B), mRNA. /FEA=mRNA /GEN=ATP6N1B /PROD=ATPase, H(+)-transporting, lysosomal,noncatalytic accessory protein 1B /DB_XREF=gi:10190665 /UG=Hs.98967 ATPase, H(+)-transporting, lysosomal, noncatalytic accessory protein 1B /FL=gb:NM_020632.1 gb:AF245517.1 NM_020632 ATPase, H+ transporting, lysosomal V0 subunit a4 ATP6V0A4 50617 NM_020632 /// NM_130840 /// NM_130841 /// XM_005250393 /// XM_005250394 0001503 // ossification // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006885 // regulation of pH // inferred from mutant phenotype /// 0007588 // excretion // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from mutant phenotype /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031526 // brush border membrane // inferred from direct assay /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 220198_s_at NM_020390 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020390.2 /DEF=Homo sapiens eukaryotic translation initiation factor 5A2 (EIF5A2), mRNA. /FEA=mRNA /GEN=EIF5A2 /PROD=eIF-5A2 protein /DB_XREF=gi:11181773 /UG=Hs.104660 eukaryotic translation initiation factor 5A2 /FL=gb:NM_020390.2 NM_020390 eukaryotic translation initiation factor 5A2 EIF5A2 56648 NM_020390 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0010509 // polyamine homeostasis // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from electronic annotation /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation 220199_s_at NM_022831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022831.1 /DEF=Homo sapiens hypothetical protein FLJ12806 (FLJ12806), mRNA. /FEA=mRNA /GEN=FLJ12806 /PROD=hypothetical protein FLJ12806 /DB_XREF=gi:12383075 /UG=Hs.107637 hypothetical protein FLJ12806 /FL=gb:NM_022831.1 NM_022831 axin interactor, dorsalization associated AIDA 64853 NM_022831 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from sequence or structural similarity /// 0043496 // regulation of protein homodimerization activity // inferred from sequence or structural similarity /// 0043508 // negative regulation of JUN kinase activity // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 220200_s_at NM_020382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020382.1 /DEF=Homo sapiens PRSET domain containing protein 07 (SET07), mRNA. /FEA=mRNA /GEN=SET07 /PROD=PRSET domain containing protein 07 /DB_XREF=gi:9966854 /UG=Hs.111988 PRSET domain containing protein 07 /FL=gb:AF287261.1 gb:NM_020382.1 NM_020382 SET domain containing (lysine methyltransferase) 8 SETD8 387893 NM_020382 /// XM_006719394 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018026 // peptidyl-lysine monomethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0043516 // regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay 220201_at NM_018835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018835.1 /DEF=Homo sapiens membrane-associated nucleic acid binding protein (MNAB), mRNA. /FEA=mRNA /GEN=MNAB /PROD=membrane-associated nucleic acid bindingprotein /DB_XREF=gi:9256536 /UG=Hs.112227 membrane-associated nucleic acid binding protein /FL=gb:NM_018835.1 NM_018835 ring finger and CCCH-type domains 2 RC3H2 54542 NM_001100588 /// NM_018835 0000209 // protein polyubiquitination // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220202_s_at NM_018835 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018835.1 /DEF=Homo sapiens membrane-associated nucleic acid binding protein (MNAB), mRNA. /FEA=mRNA /GEN=MNAB /PROD=membrane-associated nucleic acid bindingprotein /DB_XREF=gi:9256536 /UG=Hs.112227 membrane-associated nucleic acid binding protein /FL=gb:NM_018835.1 NM_018835 ring finger and CCCH-type domains 2 RC3H2 54542 NM_001100588 /// NM_018835 0000209 // protein polyubiquitination // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220203_at NM_024732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024732.1 /DEF=Homo sapiens hypothetical protein FLJ14351 (FLJ14351), mRNA. /FEA=mRNA /GEN=FLJ14351 /PROD=hypothetical protein FLJ14351 /DB_XREF=gi:13376049 /UG=Hs.116104 hypothetical protein FLJ14351 /FL=gb:NM_024732.1 NM_024732 bone morphogenetic protein 8a BMP8A 353500 NM_181809 /// XM_006710616 0001503 // ossification // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 220204_s_at NM_024732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024732.1 /DEF=Homo sapiens hypothetical protein FLJ14351 (FLJ14351), mRNA. /FEA=mRNA /GEN=FLJ14351 /PROD=hypothetical protein FLJ14351 /DB_XREF=gi:13376049 /UG=Hs.116104 hypothetical protein FLJ14351 /FL=gb:NM_024732.1 NM_024732 bone morphogenetic protein 8a BMP8A 353500 NM_181809 /// XM_006710616 0001503 // ossification // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 220205_at NM_013315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013315.1 /DEF=Homo sapiens transmembrane phosphatase with tensin homology (TPTE), mRNA. /FEA=mRNA /GEN=TPTE /PROD=transmembrane phosphatase with tensin homology /DB_XREF=gi:7019558 /UG=Hs.122986 transmembrane phosphatase with tensin homology /FL=gb:AF007118.1 gb:NM_013315.1 NM_013315 transmembrane phosphatase with tensin homology TPTE 7179 NM_001290224 /// NM_199259 /// NM_199260 /// NM_199261 0006470 // protein dephosphorylation // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 220206_at NM_024772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024772.1 /DEF=Homo sapiens hypothetical protein FLJ23151 (FLJ23151), mRNA. /FEA=mRNA /GEN=FLJ23151 /PROD=hypothetical protein FLJ23151 /DB_XREF=gi:13376120 /UG=Hs.137260 hypothetical protein FLJ23151 /FL=gb:NM_024772.1 NM_024772 zinc finger, MYM-type 1 ZMYM1 79830 NM_001289088 /// NM_001289089 /// NM_001289090 /// NM_001289091 /// NM_024772 /// XM_005271216 /// XM_005271218 /// XM_005271219 /// XM_005271220 /// XM_005271222 /// XM_006710904 /// XR_426627 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220207_at NM_022125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022125.1 /DEF=Homo sapiens immortalization-upregulated protein (IMUP), mRNA. /FEA=mRNA /GEN=IMUP /PROD=immortalization-upregulated protein /DB_XREF=gi:11545848 /UG=Hs.145362 immortalization-upregulated protein /FL=gb:NM_022125.1 NM_022125 Yip1 interacting factor homolog B (S. cerevisiae) YIF1B 90522 NM_001013617 /// NM_001031731 /// NM_001039671 /// NM_001039672 /// NM_001039673 /// NM_001145461 /// NM_001145462 /// NM_001145463 /// NM_033557 /// XM_005259384 /// XM_005259385 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220208_at NM_017587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017587.1 /DEF=Homo sapiens chromosome 9 open reading frame 8 (C9ORF8), mRNA. /FEA=mRNA /GEN=C9ORF8 /PROD=chromosome 9 open reading frame 8 /DB_XREF=gi:8922117 /UG=Hs.149184 chromosome 9 open reading frame 8 /FL=gb:NM_017587.1 NM_017587 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ADAMTS13 11093 NM_139025 /// NM_139026 /// NM_139027 /// NM_139028 /// NR_024514 0006508 // proteolysis // inferred from direct assay /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0009100 // glycoprotein metabolic process // non-traceable author statement /// 0016485 // protein processing // traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0043171 // peptide catabolic process // inferred from direct assay /// 0070670 // response to interleukin-4 // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220209_at NM_021093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021093.1 /DEF=Homo sapiens peptide YY, 2 (seminalplasmin) (PYY2), mRNA. /FEA=mRNA /GEN=PYY2 /PROD=peptide YY, 2 (seminalplasmin) /DB_XREF=gi:11036649 /UG=Hs.157195 peptide YY, 2 (seminalplasmin) /FL=gb:NM_021093.1 gb:AF222904.1 NM_021093 peptide YY, 2 (pseudogene) PYY2 23615 NM_021093 /// NR_003064 0005576 // extracellular region // inferred from electronic annotation 220210_at NM_020402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020402.2 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 10 (CHRNA10), mRNA. /FEA=mRNA /GEN=CHRNA10 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 10 /DB_XREF=gi:11138122 /UG=Hs.157714 cholinergic receptor, nicotinic, alpha polypeptide 10 /FL=gb:AF199235.2 gb:NM_020402.2 NM_020402 cholinergic receptor, nicotinic, alpha 10 (neuronal) CHRNA10 57053 NM_020402 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation 220211_at NM_024799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024799.1 /DEF=Homo sapiens hypothetical protein FLJ13224 (FLJ13224), mRNA. /FEA=mRNA /GEN=FLJ13224 /PROD=hypothetical protein FLJ13224 /DB_XREF=gi:13376172 /UG=Hs.159054 hypothetical protein FLJ13224 /FL=gb:NM_024799.1 NM_024799 uncharacterized LOC79857 FLJ13224 79857 NM_024799 /// NR_026806 220212_s_at NM_022065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022065.1 /DEF=Homo sapiens hypothetical protein FLJ21877 (FLJ21877), mRNA. /FEA=mRNA /GEN=FLJ21877 /PROD=hypothetical protein FLJ21877 /DB_XREF=gi:11545774 /UG=Hs.16063 hypothetical protein FLJ21877 /FL=gb:NM_022065.1 gb:AF323176.1 NM_022065 thyroid adenoma associated THADA 63892 NM_001083953 /// NM_001271643 /// NM_001271644 /// NM_022065 /// NR_073394 /// XM_006712061 /// XM_006712062 /// XM_006712063 /// XM_006712064 /// XM_006712065 /// XM_006712066 /// XM_006712067 /// XM_006712068 /// XM_006712069 /// XR_426993 0005488 // binding // inferred from electronic annotation 220213_at NM_018692 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018692.1 /DEF=Homo sapiens hypothetical protein OVC10-2 (OVC10-2), mRNA. /FEA=mRNA /GEN=OVC10-2 /PROD=hypothetical protein OVC10-2 /DB_XREF=gi:8923947 /UG=Hs.161281 hypothetical protein OVC10-2 /FL=gb:AF230201.1 gb:NM_018692.1 NM_018692 teashirt zinc finger homeobox 2 TSHZ2 128553 NM_001193421 /// NM_173485 /// XM_006723697 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220214_at NM_013250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013250.1 /DEF=Homo sapiens zinc finger protein 215 (ZNF215), mRNA. /FEA=mRNA /GEN=ZNF215 /PROD=zinc finger protein 215 /DB_XREF=gi:7019582 /UG=Hs.161427 zinc finger protein 215 /FL=gb:AF056618.1 gb:NM_013250.1 NM_013250 zinc finger protein 215 ZNF215 7762 NM_013250 /// XM_005253130 /// XM_006718311 /// XM_006718312 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 220215_at NM_024804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024804.1 /DEF=Homo sapiens hypothetical protein FLJ12606 (FLJ12606), mRNA. /FEA=mRNA /GEN=FLJ12606 /PROD=hypothetical protein FLJ12606 /DB_XREF=gi:13376182 /UG=Hs.163754 hypothetical protein FLJ12606 /FL=gb:NM_024804.1 NM_024804 zinc finger protein 669 ZNF669 79862 NM_001142572 /// NM_024804 /// XM_005273270 /// XM_005273271 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220216_at NM_019607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019607.1 /DEF=Homo sapiens hypothetical protein FLJ11267 (FLJ11267), mRNA. /FEA=mRNA /GEN=FLJ11267 /PROD=hypothetical protein FLJ11267 /DB_XREF=gi:9624987 /UG=Hs.165741 hypothetical protein FLJ11267 /FL=gb:NM_019607.1 NM_019607 chromosome 8 open reading frame 44 C8orf44 56260 NM_019607 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 220217_x_at NM_022661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022661.1 /DEF=Homo sapiens SPANX family, member C (SPANXC), mRNA. /FEA=mRNA /GEN=SPANXC /PROD=SPANX family, member C /DB_XREF=gi:13435136 /UG=Hs.178053 SPANX family, member C /FL=gb:NM_022661.1 gb:BC005382.1 NM_022661 sperm protein associated with the nucleus, X-linked, family member A1 /// SPANX family, member A2 /// SPANX family, member C SPANXA1 /// SPANXA2 /// SPANXC 30014 /// 64663 /// 728712 NM_013453 /// NM_022661 /// NM_145662 0007283 // spermatogenesis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 220218_at NM_017985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017985.1 /DEF=Homo sapiens hypothetical protein FLJ10058 (FLJ10058), mRNA. /FEA=mRNA /GEN=FLJ10058 /PROD=hypothetical protein FLJ10058 /DB_XREF=gi:8922211 /UG=Hs.179615 hypothetical protein FLJ10058 /FL=gb:NM_017985.1 NM_017985 spermatogenesis associated 6-like SPATA6L 55064 NM_001039395 /// NM_017985 /// XM_005251499 /// XM_006716795 /// XM_006716796 /// XM_006716797 /// XM_006716798 /// XM_006716799 /// XM_006716800 /// XM_006716801 /// XM_006716802 /// XM_006716803 /// XR_242509 /// XR_242510 220219_s_at NM_018001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018001.1 /DEF=Homo sapiens hypothetical protein FLJ10120 (FLJ10120), mRNA. /FEA=mRNA /GEN=FLJ10120 /PROD=hypothetical protein FLJ10120 /DB_XREF=gi:8922238 /UG=Hs.190488 hypothetical protein FLJ10120 /FL=gb:NM_018001.1 NM_018001 leucine rich repeat containing 37A /// leucine rich repeat containing 37, member A2 /// leucine rich repeat containing 37, member A3 /// leucine rich repeat containing 37, member A4, pseudogene LRRC37A /// LRRC37A2 /// LRRC37A3 /// LRRC37A4P 9884 /// 55073 /// 374819 /// 474170 NM_001006607 /// NM_014834 /// NM_018001 /// NM_199340 /// NR_002940 /// XM_005257878 /// XM_005257879 /// XM_005257880 /// XM_005257882 /// XM_005257883 /// XM_005257884 /// XM_005257887 /// XM_005275659 /// XM_005275660 /// XM_005275662 /// XM_005275664 /// XM_005275665 /// XM_005275667 /// XM_005275669 /// XM_006722208 /// XM_006722209 /// XM_006722210 /// XM_006722211 /// XM_006722212 /// XM_006722213 /// XM_006725279 /// XM_006725280 /// XM_006725281 /// XM_006725282 /// XM_006725283 /// XR_430756 /// XR_430757 /// XR_430758 /// XR_430759 /// XR_430760 /// XR_430761 /// XR_430762 /// XR_430763 /// XR_430764 /// XR_430765 /// XR_430766 /// XR_430767 /// XR_430768 /// XR_430769 /// XR_430770 /// XR_430771 /// XR_430772 /// XR_430773 /// XR_430774 /// XR_430775 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220220_at NM_018001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018001.1 /DEF=Homo sapiens hypothetical protein FLJ10120 (FLJ10120), mRNA. /FEA=mRNA /GEN=FLJ10120 /PROD=hypothetical protein FLJ10120 /DB_XREF=gi:8922238 /UG=Hs.190488 hypothetical protein FLJ10120 /FL=gb:NM_018001.1 NM_018001 leucine rich repeat containing 37, member A2 /// leucine rich repeat containing 37, member A4, pseudogene LRRC37A2 /// LRRC37A4P 55073 /// 474170 NM_001006607 /// NM_018001 /// NR_002940 /// XR_430756 /// XR_430757 /// XR_430758 /// XR_430759 /// XR_430760 /// XR_430761 /// XR_430762 /// XR_430763 /// XR_430764 /// XR_430765 /// XR_430766 /// XR_430767 /// XR_430768 /// XR_430769 /// XR_430770 /// XR_430771 /// XR_430772 /// XR_430773 /// XR_430774 /// XR_430775 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220221_at NM_018156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018156.1 /DEF=Homo sapiens hypothetical protein FLJ10619 (FLJ10619), mRNA. /FEA=mRNA /GEN=FLJ10619 /PROD=hypothetical protein FLJ10619 /DB_XREF=gi:8922552 /UG=Hs.191436 hypothetical protein FLJ10619 /FL=gb:NM_018156.1 NM_018156 vacuolar protein sorting 13 homolog D (S. cerevisiae) VPS13D 55187 NM_015378 /// NM_018156 0070062 // extracellular vesicular exosome // inferred from direct assay 220222_at NM_018608 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018608.1 /DEF=Homo sapiens hypothetical protein PRO1905 (PRO1905), mRNA. /FEA=mRNA /GEN=PRO1905 /PROD=hypothetical protein PRO1905 /DB_XREF=gi:8924095 /UG=Hs.192788 hypothetical protein PRO1905 /FL=gb:AF116672.1 gb:NM_018608.1 NM_018608 RBM12B antisense RNA 1 RBM12B-AS1 55472 NM_018608 /// NR_027259 220223_at NM_024857 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024857.1 /DEF=Homo sapiens hypothetical protein FLJ12735 (FLJ12735), mRNA. /FEA=mRNA /GEN=FLJ12735 /PROD=hypothetical protein FLJ12735 /DB_XREF=gi:13376283 /UG=Hs.192974 hypothetical protein FLJ12735 /FL=gb:NM_024857.1 NM_024857 ATPase family, AAA domain containing 5 ATAD5 79915 NM_024857 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 220224_at NM_017545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017545.2 /DEF=Homo sapiens hydroxyacid oxidase (glycolate oxidase) 1 (HAO1), mRNA. /FEA=mRNA /GEN=HAO1 /PROD=hydroxyacid oxidase 1 /DB_XREF=gi:11184232 /UG=Hs.193640 hydroxyacid oxidase (glycolate oxidase) 1 /FL=gb:NM_017545.2 gb:AB024079.1 gb:AF231916.1 gb:AF244134.1 NM_017545 hydroxyacid oxidase (glycolate oxidase) 1 HAO1 54363 NM_017545 0001561 // fatty acid alpha-oxidation // inferred from direct assay /// 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046296 // glycolate catabolic process // inferred from direct assay /// 0046296 // glycolate catabolic process // inferred from electronic annotation /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003973 // (S)-2-hydroxy-acid oxidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0008891 // glycolate oxidase activity // inferred from direct assay /// 0008891 // glycolate oxidase activity // traceable author statement /// 0010181 // FMN binding // inferred from direct assay /// 0015930 // glutamate synthase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016638 // oxidoreductase activity, acting on the CH-NH2 group of donors // inferred from electronic annotation /// 0047969 // glyoxylate oxidase activity // traceable author statement /// 0052852 // very-long-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation /// 0052853 // long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity // inferred from electronic annotation /// 0052854 // medium-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation 220225_at NM_016358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016358.1 /DEF=Homo sapiens iroquois homeobox protein 4 (IRX4), mRNA. /FEA=mRNA /GEN=IRX4 /PROD=iroquois homeobox protein 4 /DB_XREF=gi:7705554 /UG=Hs.196927 iroquois homeobox protein 4 /FL=gb:AF124733.1 gb:NM_016358.1 NM_016358 iroquois homeobox 4 IRX4 50805 NM_001278632 /// NM_001278633 /// NM_001278634 /// NM_001278635 /// NM_016358 /// XM_006714476 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0048561 // establishment of organ orientation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220226_at NM_024080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024080.1 /DEF=Homo sapiens hypothetical protein MGC2849 (MGC2849), mRNA. /FEA=mRNA /GEN=MGC2849 /PROD=hypothetical protein MGC2849 /DB_XREF=gi:13129071 /UG=Hs.197733 hypothetical protein MGC2849 /FL=gb:BC001135.1 gb:NM_024080.1 NM_024080 transient receptor potential cation channel, subfamily M, member 8 TRPM8 79054 NM_024080 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0009266 // response to temperature stimulus // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050955 // thermoception // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 220227_at NM_024883 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024883.1 /DEF=Homo sapiens hypothetical protein FLJ22202 (FLJ22202), mRNA. /FEA=mRNA /GEN=FLJ22202 /PROD=hypothetical protein FLJ22202 /DB_XREF=gi:13376328 /UG=Hs.217754 hypothetical protein FLJ22202 /FL=gb:NM_024883.1 NM_024883 cadherin 4, type 1, R-cadherin (retinal) CDH4 1002 NM_001252338 /// NM_001252339 /// NM_001794 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220228_at AB030653 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB030653.1 /DEF=Homo sapiens mRNA for epsilon-adaptin, complete cds. /FEA=mRNA /PROD=epsilon-adaptin /DB_XREF=gi:5689376 /UG=Hs.218028 adaptor-related protein complex 4, epsilon 1 subunit /FL=gb:AB030653.1 gb:NM_007347.1 gb:AF155156.2 AB030653 adaptor-related protein complex 4, epsilon 1 subunit AP4E1 23431 NM_001252127 /// NM_007347 /// XM_005254264 /// XM_006720447 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation 220229_s_at NM_007347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007347.1 /DEF=Homo sapiens adaptor-related protein complex 4, epsilon 1 subunit (AP4E1), mRNA. /FEA=mRNA /GEN=AP4E1 /PROD=adaptor-related protein complex 4, epsilon 1subunit /DB_XREF=gi:6671550 /UG=Hs.218028 adaptor-related protein complex 4, epsilon 1 subunit /FL=gb:AB030653.1 gb:NM_007347.1 gb:AF155156.2 NM_007347 adaptor-related protein complex 4, epsilon 1 subunit AP4E1 23431 NM_001252127 /// NM_007347 /// XM_005254264 /// XM_006720447 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 220230_s_at NM_016229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016229.1 /DEF=Homo sapiens cytochrome b5 reductase b5R.2 (LOC51700), mRNA. /FEA=mRNA /GEN=LOC51700 /PROD=cytochrome b5 reductase b5R.2 /DB_XREF=gi:7706442 /UG=Hs.22142 cytochrome b5 reductase b5R.2 /FL=gb:AF169802.1 gb:NM_016229.1 NM_016229 cytochrome b5 reductase 2 CYB5R2 51700 NM_001001336 /// NM_016229 /// XM_005252973 /// XM_005252974 /// XM_005252975 /// XM_005252976 /// XM_006718250 /// XM_006718251 /// XM_006718252 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 220231_at NM_006658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006658.1 /DEF=Homo sapiens G-substrate (GSBS), mRNA. /FEA=mRNA /GEN=GSBS /PROD=G-substrate /DB_XREF=gi:5729859 /UG=Hs.227011 G-substrate /FL=gb:AF071789.1 gb:AF097730.1 gb:NM_006658.1 NM_006658 protein phosphatase 1, regulatory subunit 17 PPP1R17 10842 NM_001145123 /// NM_006658 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0007610 // behavior // traceable author statement /// 0010921 // regulation of phosphatase activity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0004865 // protein serine/threonine phosphatase inhibitor activity // inferred from electronic annotation /// 0019212 // phosphatase inhibitor activity // inferred from electronic annotation 220232_at NM_024906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024906.1 /DEF=Homo sapiens hypothetical protein FLJ21032 (FLJ21032), mRNA. /FEA=mRNA /GEN=FLJ21032 /PROD=hypothetical protein FLJ21032 /DB_XREF=gi:13376362 /UG=Hs.247474 hypothetical protein FLJ21032 /FL=gb:NM_024906.1 NM_024906 stearoyl-CoA desaturase 5 SCD5 79966 NM_001037582 /// NM_024906 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220233_at NM_024907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024907.1 /DEF=Homo sapiens hypothetical protein FLJ11798 (FLJ11798), mRNA. /FEA=mRNA /GEN=FLJ11798 /PROD=hypothetical protein FLJ11798 /DB_XREF=gi:13376364 /UG=Hs.249727 hypothetical protein FLJ11798 /FL=gb:NM_024907.1 NM_024907 F-box protein 17 FBXO17 115290 NM_024907 /// NM_148169 /// NR_104026 0030163 // protein catabolic process // inferred from electronic annotation 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 220234_at NM_004056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004056.2 /DEF=Homo sapiens carbonic anhydrase VIII (CA8), mRNA. /FEA=mRNA /GEN=CA8 /PROD=carbonic anhydrase VIII /DB_XREF=gi:5148943 /UG=Hs.250502 carbonic anhydrase VIII /FL=gb:NM_004056.2 NM_004056 carbonic anhydrase VIII CA8 767 NM_004056 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220235_s_at NM_018372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018372.1 /DEF=Homo sapiens hypothetical protein FLJ11269 (FLJ11269), mRNA. /FEA=mRNA /GEN=FLJ11269 /PROD=hypothetical protein FLJ11269 /DB_XREF=gi:8922961 /UG=Hs.25245 hypothetical protein FLJ11269 /FL=gb:NM_018372.1 NM_018372 ligand dependent nuclear receptor interacting factor 1 LRIF1 55791 NM_001006945 /// NM_018372 /// XM_005271029 /// XM_006710763 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation 220236_at NM_017990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017990.2 /DEF=Homo sapiens hypothetical protein FLJ10079 (FLJ10079), mRNA. /FEA=mRNA /GEN=FLJ10079 /PROD=hypothetical protein FLJ10079 /DB_XREF=gi:13775157 /UG=Hs.261215 hypothetical protein FLJ10079 /FL=gb:NM_017990.2 NM_017990 pyruvate dehydrogenase phosphatase regulatory subunit PDPR 55066 NM_017990 /// XM_005256015 /// XM_005256016 /// XM_005256019 /// XM_006721224 /// XM_006721225 /// XM_006721226 /// XR_429721 0006090 // pyruvate metabolic process // traceable author statement /// 0006546 // glycine catabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 220237_at NM_022488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022488.1 /DEF=Homo sapiens PC3-96 protein (PC3-96), mRNA. /FEA=mRNA /GEN=PC3-96 /PROD=PC3-96 protein /DB_XREF=gi:11968042 /UG=Hs.26367 PC3-96 protein /FL=gb:NM_022488.1 NM_022488 autophagy related 3 ATG3 64422 NM_001278712 /// NM_022488 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006501 // C-terminal protein lipidation // not recorded /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from sequence or structural similarity /// 0044804 // nucleophagy // /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0000153 // cytoplasmic ubiquitin ligase complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019776 // Atg8 ligase activity // not recorded /// 0019776 // Atg8 ligase activity // inferred from sequence or structural similarity /// 0019777 // Atg12 ligase activity // inferred from sequence or structural similarity /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 220238_s_at NM_018846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018846.1 /DEF=Homo sapiens SBBI26 protein (SBBI26), mRNA. /FEA=mRNA /GEN=SBBI26 /PROD=SBBI26 protein /DB_XREF=gi:9055325 /UG=Hs.26481 SBBI26 protein /FL=gb:AF111113.1 gb:NM_018846.1 NM_018846 kelch-like family member 7 KLHL7 55975 NM_001031710 /// NM_001172428 /// NM_018846 /// NR_033328 /// NR_033329 /// XM_006715753 /// XM_006715754 /// XM_006715755 /// XM_006715756 /// XM_006715757 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 220239_at NM_018846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018846.1 /DEF=Homo sapiens SBBI26 protein (SBBI26), mRNA. /FEA=mRNA /GEN=SBBI26 /PROD=SBBI26 protein /DB_XREF=gi:9055325 /UG=Hs.26481 SBBI26 protein /FL=gb:AF111113.1 gb:NM_018846.1 NM_018846 kelch-like family member 7 KLHL7 55975 NM_001031710 /// NM_001172428 /// NM_018846 /// NR_033328 /// NR_033329 /// XM_006715753 /// XM_006715754 /// XM_006715755 /// XM_006715756 /// XM_006715757 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 220240_s_at NM_017905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017905.1 /DEF=Homo sapiens hypothetical protein FLJ20623 (FLJ20623), mRNA. /FEA=mRNA /GEN=FLJ20623 /PROD=hypothetical protein FLJ20623 /DB_XREF=gi:8923574 /UG=Hs.27337 hypothetical protein FLJ20623 /FL=gb:NM_017905.1 NM_017905 transmembrane and coiled-coil domains 3 TMCO3 55002 NM_017905 /// XM_005268318 /// XM_005268319 /// XM_006719969 /// XM_006719970 /// XM_006719971 /// XM_006719972 /// XM_006719973 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation 220241_at NM_017905 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017905.1 /DEF=Homo sapiens hypothetical protein FLJ20623 (FLJ20623), mRNA. /FEA=mRNA /GEN=FLJ20623 /PROD=hypothetical protein FLJ20623 /DB_XREF=gi:8923574 /UG=Hs.27337 hypothetical protein FLJ20623 /FL=gb:NM_017905.1 NM_017905 transmembrane and coiled-coil domains 3 TMCO3 55002 NM_017905 /// XM_005268318 /// XM_005268319 /// XM_006719969 /// XM_006719970 /// XM_006719971 /// XM_006719972 /// XM_006719973 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation 220242_x_at NM_018260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018260.1 /DEF=Homo sapiens hypothetical protein FLJ10891 (FLJ10891), mRNA. /FEA=mRNA /GEN=FLJ10891 /PROD=hypothetical protein FLJ10891 /DB_XREF=gi:8922743 /UG=Hs.274169 hypothetical protein FLJ10891 /FL=gb:NM_018260.1 NM_018260 zinc finger protein 701 ZNF701 55762 NM_001172655 /// NM_018260 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220243_at NM_014155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014155.1 /DEF=Homo sapiens HSPC063 protein (HSPC063), mRNA. /FEA=mRNA /GEN=HSPC063 /PROD=HSPC063 protein /DB_XREF=gi:7661765 /UG=Hs.278947 HSPC063 protein /FL=gb:AF161548.1 gb:NM_014155.1 NM_014155 zinc finger and BTB domain containing 44 ZBTB44 29068 NM_014155 /// XM_005271521 /// XM_005271522 /// XM_005271523 /// XM_005271524 /// XM_005271525 /// XM_005271526 /// XM_006718825 /// XM_006718826 /// XR_246421 /// XR_246423 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220244_at NM_013343 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013343.1 /DEF=Homo sapiens NAG-7 protein (NAG-7), mRNA. /FEA=mRNA /GEN=NAG-7 /PROD=NAG-7 protein /DB_XREF=gi:7106370 /UG=Hs.278951 NAG-7 protein /FL=gb:AF086709.2 gb:NM_013343.1 NM_013343 long intergenic non-protein coding RNA 312 LINC00312 29931 NM_013343 /// NR_024065 220245_at NM_016180 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016180.1 /DEF=Homo sapiens AIM-1 protein (LOC51151), mRNA. /FEA=mRNA /GEN=LOC51151 /PROD=AIM-1 protein /DB_XREF=gi:7705868 /UG=Hs.278962 AIM-1 protein /FL=gb:AF172849.1 gb:NM_016180.1 NM_016180 solute carrier family 45, member 2 SLC45A2 51151 NM_001012509 /// NM_001297417 /// NM_016180 /// XM_005248311 0007601 // visual perception // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation 220246_at NM_020397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020397.1 /DEF=Homo sapiens CamKI-like protein kinase (LOC57118), mRNA. /FEA=mRNA /GEN=LOC57118 /PROD=CamKI-like protein kinase /DB_XREF=gi:9966874 /UG=Hs.279788 CamKI-like protein kinase /FL=gb:AF286366.1 gb:NM_020397.1 NM_020397 calcium/calmodulin-dependent protein kinase ID CAMK1D 57118 NM_020397 /// NM_153498 /// XM_006717481 /// XM_006717482 /// XM_006717483 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032793 // positive regulation of CREB transcription factor activity // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from mutant phenotype /// 0050773 // regulation of dendrite development // inferred from mutant phenotype /// 0060267 // positive regulation of respiratory burst // inferred from mutant phenotype /// 0071622 // regulation of granulocyte chemotaxis // inferred from mutant phenotype /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005954 // calcium- and calmodulin-dependent protein kinase complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220247_at NM_020380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020380.1 /DEF=Homo sapiens AF15q14 protein (AF15Q14), mRNA. /FEA=mRNA /GEN=AF15Q14 /PROD=AF15q14 protein /DB_XREF=gi:9966806 /UG=Hs.283099 AF15q14 protein /FL=gb:AF248041.1 gb:NM_020380.1 NM_020380 cancer susceptibility candidate 5 CASC5 57082 NM_144508 /// NM_170589 0000278 // mitotic cell cycle // traceable author statement /// 0001675 // acrosome assembly // non-traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220248_x_at NM_018839 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018839.1 /DEF=Homo sapiens p47 protein (LOC55968), mRNA. /FEA=mRNA /GEN=LOC55968 /PROD=p47 protein /DB_XREF=gi:10047113 /UG=Hs.284261 p47 protein /FL=gb:NM_018839.1 gb:AF112211.1 NM_018839 NSFL1 (p97) cofactor (p47) NSFL1C 55968 NM_001206736 /// NM_016143 /// NM_018839 /// NM_182483 /// NR_038164 /// XM_006723591 /// XM_006723592 /// XM_006723593 /// XM_006723594 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 220249_at NM_012269 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012269.1 /DEF=Homo sapiens hyaluronoglucosaminidase 4 (HYAL4), mRNA. /FEA=mRNA /GEN=HYAL4 /PROD=hyaluronoglucosaminidase 4 /DB_XREF=gi:6912427 /UG=Hs.28673 hyaluronoglucosaminidase 4 /FL=gb:AF009010.1 gb:NM_012269.1 NM_012269 hyaluronoglucosaminidase 4 HYAL4 23553 NM_012269 /// XM_005250238 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030207 // chondroitin sulfate catabolic process // inferred from electronic annotation 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 220250_at NM_020652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020652.1 /DEF=Homo sapiens zinc finger protein ZNF286 (ZNF286), mRNA. /FEA=mRNA /GEN=ZNF286 /PROD=zinc finger protein ZNF286 /DB_XREF=gi:10190685 /UG=Hs.287331 zinc finger protein ZNF286 /FL=gb:NM_020652.1 gb:AF217226.1 NM_020652 zinc finger protein 286A ZNF286A 57335 NM_001130842 /// NM_001288642 /// NM_001288643 /// NM_001288644 /// NM_001288645 /// NM_001288646 /// NM_001288647 /// NM_001288648 /// NM_001288649 /// NM_020652 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220251_at NM_024998 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024998.1 /DEF=Homo sapiens hypothetical protein FLJ12704 (FLJ12704), mRNA. /FEA=mRNA /GEN=FLJ12704 /PROD=hypothetical protein FLJ12704 /DB_XREF=gi:13376508 /UG=Hs.287541 hypothetical protein FLJ12704 /FL=gb:NM_024998.1 NM_024998 digestive organ expansion factor homolog (zebrafish) DIEXF 27042 NM_014388 /// XM_006711275 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 220252_x_at NM_025159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025159.1 /DEF=Homo sapiens hypothetical protein FLJ11577 (FLJ11577), mRNA. /FEA=mRNA /GEN=FLJ11577 /PROD=hypothetical protein FLJ11577 /DB_XREF=gi:13376758 /UG=Hs.289065 hypothetical protein FLJ11577 /FL=gb:NM_025159.1 NM_025159 chromosome X open reading frame 21 CXorf21 80231 NM_025159 220253_s_at NM_013437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013437.1 /DEF=Homo sapiens potential tumor suppressor (ST7), mRNA. /FEA=mRNA /GEN=ST7 /PROD=potential tumor suppressor /DB_XREF=gi:7305524 /UG=Hs.301974 potential tumor suppressor /FL=gb:AF166350.1 gb:NM_013437.1 NM_013437 low density lipoprotein receptor-related protein 12 LRP12 29967 NM_001135703 /// NM_013437 0006897 // endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005041 // low-density lipoprotein receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220254_at NM_013437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013437.1 /DEF=Homo sapiens potential tumor suppressor (ST7), mRNA. /FEA=mRNA /GEN=ST7 /PROD=potential tumor suppressor /DB_XREF=gi:7305524 /UG=Hs.301974 potential tumor suppressor /FL=gb:AF166350.1 gb:NM_013437.1 NM_013437 low density lipoprotein receptor-related protein 12 LRP12 29967 NM_001135703 /// NM_013437 0006897 // endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005041 // low-density lipoprotein receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220255_at NM_021922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021922.1 /DEF=Homo sapiens Fanconi anemia, complementation group E (FANCE), mRNA. /FEA=mRNA /GEN=FANCE /PROD=Fanconi anemia, complementation group E /DB_XREF=gi:11345453 /UG=Hs.302003 Fanconi anemia, complementation group E /FL=gb:AF265210.1 gb:NM_021922.1 NM_021922 Fanconi anemia, complementation group E FANCE 2178 NM_021922 /// XM_005248885 /// XM_005248886 /// XM_005248887 /// XM_005248888 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220256_s_at NM_022120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022120.1 /DEF=Homo sapiens hypothetical protein FKSG25 (FLJ00030), mRNA. /FEA=mRNA /GEN=FLJ00030 /PROD=hypothetical protein FKSG25 /DB_XREF=gi:11545840 /UG=Hs.302023 hypothetical protein FKSG25 /FL=gb:AY013700.1 gb:NM_022120.1 NM_022120 3-oxoacid CoA transferase 2 OXCT2 64064 NM_022120 0008152 // metabolic process // inferred from electronic annotation /// 0046952 // ketone body catabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0031514 // motile cilium // inferred from direct assay 0008260 // 3-oxoacid CoA-transferase activity // inferred from electronic annotation /// 0008410 // CoA-transferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 220257_x_at NM_017809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017809.1 /DEF=Homo sapiens hypothetical protein FLJ20416 (FLJ20416), mRNA. /FEA=mRNA /GEN=FLJ20416 /PROD=hypothetical protein FLJ20416 /DB_XREF=gi:8923383 /UG=Hs.306209 nuclear RNA export factor 2 /FL=gb:NM_017809.1 NM_017809 nuclear RNA export factor 2 /// nuclear RNA export factor 2B NXF2 /// NXF2B 56001 /// 728343 NM_001039910 /// NM_001099686 /// NM_017809 /// NM_022053 /// XM_006710259 0006406 // mRNA export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0050658 // RNA transport // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220258_s_at NM_018081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018081.1 /DEF=Homo sapiens hypothetical protein FLJ10385 (FLJ10385), mRNA. /FEA=mRNA /GEN=FLJ10385 /PROD=hypothetical protein FLJ10385 /DB_XREF=gi:8922395 /UG=Hs.30922 hypothetical protein FLJ10385 /FL=gb:NM_018081.1 NM_018081 WD repeat containing, antisense to TP53 WRAP53 55135 NM_001143990 /// NM_001143991 /// NM_001143992 /// NM_018081 /// XR_429818 0032203 // telomere formation via telomerase // inferred from mutant phenotype /// 0051973 // positive regulation of telomerase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 220259_at NM_024927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024927.1 /DEF=Homo sapiens hypothetical protein FLJ21019 (FLJ21019), mRNA. /FEA=mRNA /GEN=FLJ21019 /PROD=hypothetical protein FLJ21019 /DB_XREF=gi:13376401 /UG=Hs.312705 hypothetical protein FLJ21019 /FL=gb:NM_024927.1 NM_024927 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 PLEKHH3 79990 NM_024927 /// NR_073573 /// NR_073574 /// XM_006722096 /// XM_006722097 /// XR_429922 /// XR_429923 0007165 // signal transduction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 220260_at NM_018317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018317.1 /DEF=Homo sapiens hypothetical protein FLJ11082 (FLJ11082), mRNA. /FEA=mRNA /GEN=FLJ11082 /PROD=hypothetical protein FLJ11082 /DB_XREF=gi:8922855 /UG=Hs.31792 hypothetical protein FLJ11082 /FL=gb:NM_018317.1 NM_018317 TBC1 domain family, member 19 TBC1D19 55296 NM_001292054 /// NM_018317 /// XM_005248172 /// XM_006713967 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 220261_s_at NM_018106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018106.1 /DEF=Homo sapiens hypothetical protein FLJ10479 (FLJ10479), mRNA. /FEA=mRNA /GEN=FLJ10479 /PROD=hypothetical protein FLJ10479 /DB_XREF=gi:8922447 /UG=Hs.5268 hypothetical protein FLJ10479 /FL=gb:AL136674.1 gb:BC001239.1 gb:NM_018106.1 NM_018106 zinc finger, DHHC-type containing 4 ZDHHC4 55146 NM_001134387 /// NM_001134388 /// NM_001134389 /// NM_018106 /// XM_005249793 /// XM_005249794 /// XM_005249795 /// XM_005249796 /// XM_006715750 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220262_s_at NM_023932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023932.1 /DEF=Homo sapiens hypothetical protein MGC2487 (MGC2487), mRNA. /FEA=mRNA /GEN=MGC2487 /PROD=hypothetical protein MGC2487 /DB_XREF=gi:13027595 /UG=Hs.55879 hypothetical protein MGC2487 /FL=gb:BC000230.1 gb:NM_023932.1 NM_023932 delta-like 2 homolog (Drosophila) DLK2 65989 NM_001286655 /// NM_001286656 /// NM_023932 /// NM_206539 /// XM_005249308 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220263_at NM_022001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022001.1 /DEF=Homo sapiens SMAD in the antisense orientation (DAMS), mRNA. /FEA=mRNA /GEN=DAMS /PROD=SMAD in the antisense orientation /DB_XREF=gi:11545925 /UG=Hs.59666 SMAD in the antisense orientation /FL=gb:NM_022001.1 gb:AF071111.1 NM_022001 SMAD5 antisense RNA 1 SMAD5-AS1 9597 NM_022001 /// NR_026763 0007165 // signal transduction // traceable author statement 220264_s_at NM_020960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020960.1 /DEF=Homo sapiens KIAA1624 protein (KIAA1624), mRNA. /FEA=mRNA /GEN=KIAA1624 /PROD=KIAA1624 protein /DB_XREF=gi:13470087 /UG=Hs.6639 KIAA1624 protein /FL=gb:NM_020960.1 NM_020960 G protein-coupled receptor 107 GPR107 57720 NM_001136557 /// NM_001136558 /// NM_001287346 /// NM_020960 /// XM_006717196 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220265_at NM_020960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020960.1 /DEF=Homo sapiens KIAA1624 protein (KIAA1624), mRNA. /FEA=mRNA /GEN=KIAA1624 /PROD=KIAA1624 protein /DB_XREF=gi:13470087 /UG=Hs.6639 KIAA1624 protein /FL=gb:NM_020960.1 NM_020960 G protein-coupled receptor 107 GPR107 57720 NM_001136557 /// NM_001136558 /// NM_001287346 /// NM_020960 /// XM_006717196 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220266_s_at NM_004235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004235.1 /DEF=Homo sapiens Kruppel-like factor 4 (gut) (KLF4), mRNA. /FEA=mRNA /GEN=KLF4 /PROD=Kruppel-like factor 4 (gut) /DB_XREF=gi:4758321 /UG=Hs.7934 Kruppel-like factor 4 (gut) /FL=gb:U70663.1 gb:AF022184.1 gb:NM_004235.1 gb:AF105036.1 NM_004235 Kruppel-like factor 4 (gut) KLF4 9314 NM_004235 /// XM_005252305 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007500 // mesodermal cell fate determination // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009913 // epidermal cell differentiation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014740 // negative regulation of muscle hyperplasia // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031077 // post-embryonic camera-type eye development // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0035166 // post-embryonic hemopoiesis // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045595 // regulation of cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046985 // positive regulation of hemoglobin biosynthetic process // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060761 // negative regulation of response to cytokine stimulus // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071409 // cellular response to cycloheximide // inferred from electronic annotation /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 1901653 // cellular response to peptide // inferred from electronic annotation /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001010 // sequence-specific DNA binding transcription factor recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 220267_at NM_019016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019016.1 /DEF=Homo sapiens hypothetical protein (FLJ20261), mRNA. /FEA=mRNA /GEN=FLJ20261 /PROD=hypothetical protein /DB_XREF=gi:9506668 /UG=Hs.87383 hypothetical protein /FL=gb:NM_019016.1 NM_019016 keratin 24 KRT24 192666 NM_019016 /// XM_006721739 0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation 220268_at NM_014040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014040.1 /DEF=Homo sapiens PTD015 protein (PTD015), mRNA. /FEA=mRNA /GEN=PTD015 /PROD=PTD015 protein /DB_XREF=gi:7662642 /UG=Hs.95870 PTD015 protein /FL=gb:AF092136.1 gb:NM_014040.1 NM_014040 adipogenesis associated, Mth938 domain containing AAMDC 28971 NM_024684 /// XM_005273938 0043066 // negative regulation of apoptotic process // not recorded /// 0045600 // positive regulation of fat cell differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity 220269_at NM_024687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024687.1 /DEF=Homo sapiens hypothetical protein FLJ23049 (FLJ23049), mRNA. /FEA=mRNA /GEN=FLJ23049 /PROD=hypothetical protein FLJ23049 /DB_XREF=gi:13375959 /UG=Hs.96901 hypothetical protein FLJ23049 /FL=gb:NM_024687.1 NM_024687 zinc finger, B-box domain containing ZBBX 79740 NM_001199201 /// NM_001199202 /// NM_024687 /// XM_005247777 /// XM_005247779 /// XM_006713747 /// XM_006713748 0005622 // intracellular // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220270_at NM_019038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019038.1 /DEF=Homo sapiens hypothetical protein (FLJ11045), mRNA. /FEA=mRNA /GEN=FLJ11045 /PROD=hypothetical protein /DB_XREF=gi:9506634 /UG=Hs.97464 hypothetical protein /FL=gb:NM_019038.1 NM_019038 ring finger protein 17 RNF17 56163 NM_001184993 /// NM_031277 /// NM_031994 /// XM_005266473 /// XM_006719846 /// XM_006719847 /// XM_006719848 /// XM_006719849 /// XM_006719850 /// XM_006719851 /// XM_006719852 /// XM_006719853 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220271_x_at NM_022785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022785.1 /DEF=Homo sapiens hypothetical protein FLJ23588 (FLJ23588), mRNA. /FEA=mRNA /GEN=FLJ23588 /PROD=hypothetical protein FLJ23588 /DB_XREF=gi:12232476 /UG=Hs.99330 hypothetical protein FLJ23588 /FL=gb:NM_022785.1 NM_022785 EF-hand calcium binding domain 6 EFCAB6 64800 NM_022785 /// NM_198856 /// XM_005261704 /// XM_005261705 /// XM_006724296 /// XM_006724297 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220272_at NM_017637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017637.1 /DEF=Homo sapiens hypothetical protein FLJ20043 (FLJ20043), mRNA. /FEA=mRNA /GEN=FLJ20043 /PROD=hypothetical protein FLJ20043 /DB_XREF=gi:8923050 /UG=Hs.103853 hypothetical protein FLJ20043 /FL=gb:NM_017637.1 NM_017637 basonuclin 2 BNC2 54796 NM_017637 /// XM_006716784 /// XM_006716785 /// XM_006716786 /// XM_006716787 /// XM_006716788 /// XM_006716789 /// XM_006716790 0003416 // endochondral bone growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043586 // tongue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220273_at NM_014443 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014443.1 /DEF=Homo sapiens interleukin 17B (IL17B), mRNA. /FEA=mRNA /GEN=IL17B /PROD=interleukin 17B /DB_XREF=gi:7657227 /UG=Hs.110040 interleukin 17B /FL=gb:AF110385.1 gb:AF218727.1 gb:AF184969.1 gb:AF152098.1 gb:NM_014443.1 gb:AF212311.1 NM_014443 interleukin 17B IL17B 27190 NM_014443 /// XM_006714779 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation 220274_at NM_024726 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024726.1 /DEF=Homo sapiens hypothetical protein FLJ22527 (FLJ22527), mRNA. /FEA=mRNA /GEN=FLJ22527 /PROD=hypothetical protein FLJ22527 /DB_XREF=gi:13376037 /UG=Hs.113009 hypothetical protein FLJ22527 /FL=gb:NM_024726.1 NM_024726 IQ motif containing with AAA domain 1 IQCA1 79781 NM_001270584 /// NM_001270585 /// NM_024726 /// NR_073043 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 220275_at NM_022034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022034.1 /DEF=Homo sapiens estrogen regulated gene 1 (ERG-1), mRNA. /FEA=mRNA /GEN=ERG-1 /PROD=estrogen regulated gene 1 /DB_XREF=gi:11545736 /UG=Hs.114648 estrogen regulated gene 1 /FL=gb:AF305835.1 gb:NM_022034.1 NM_022034 CUB and zona pellucida-like domains 1 CUZD1 50624 NM_022034 /// NR_037912 0006931 // substrate-dependent cell migration, cell attachment to substrate // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0032023 // trypsinogen activation // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042588 // zymogen granule // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity 220276_at NM_024730 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024730.1 /DEF=Homo sapiens hypothetical protein FLJ22655 (FLJ22655), mRNA. /FEA=mRNA /GEN=FLJ22655 /PROD=hypothetical protein FLJ22655 /DB_XREF=gi:13376045 /UG=Hs.115497 hypothetical protein FLJ22655 /FL=gb:NM_024730.1 NM_024730 RERG/RAS-like RERGL 79785 NM_001286201 /// NM_024730 /// NR_104413 /// XM_006719152 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 220277_at NM_025212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025212.1 /DEF=Homo sapiens Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex) (IDAX), mRNA. /FEA=mRNA /GEN=IDAX /PROD=Dvl-binding protein IDAX (inhibition of the Dvland Axin complex) /DB_XREF=gi:13376815 /UG=Hs.118569 Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex) /FL=gb:AF272159.1 gb:NM_025212.1 NM_025212 CXXC finger protein 4 CXXC4 80319 NM_025212 0007352 // zygotic specification of dorsal/ventral axis // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220278_at NM_018039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018039.1 /DEF=Homo sapiens hypothetical protein FLJ10251 (FLJ10251), mRNA. /FEA=mRNA /GEN=FLJ10251 /PROD=hypothetical protein FLJ10251 /DB_XREF=gi:8922310 /UG=Hs.120842 hypothetical protein FLJ10251 /FL=gb:NM_018039.1 NM_018039 lysine (K)-specific demethylase 4D KDM4D 55693 NM_018039 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033169 // histone H3-K9 demethylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 220279_at NM_016102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016102.1 /DEF=Homo sapiens ring finger protein 16 (RNF16), mRNA. /FEA=mRNA /GEN=RNF16 /PROD=ring finger protein 16 /DB_XREF=gi:7705824 /UG=Hs.121748 ring finger protein 16 /FL=gb:AF156271.1 gb:NM_016102.1 NM_016102 tripartite motif containing 17 TRIM17 51127 NM_001024940 /// NM_001024941 /// NM_001134855 /// NM_016102 /// XM_006711779 /// XM_006711780 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220280_s_at NM_016552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016552.1 /DEF=Homo sapiens testis specific ankyrin-like protein 1 (LOC51281), mRNA. /FEA=mRNA /GEN=LOC51281 /PROD=testis specific ankyrin-like protein 1 /DB_XREF=gi:7706086 /UG=Hs.122275 testis specific ankyrin-like protein 1 /FL=gb:AB034636.1 gb:NM_016552.1 NM_016552 ankyrin repeat and MYND domain containing 1 ANKMY1 51281 NM_001282771 /// NM_001282780 /// NM_001282781 /// NM_016552 /// NM_017844 /// XM_005247020 /// XM_006712567 /// XM_006712568 /// XM_006712569 /// XM_006712570 /// XM_006712571 /// XM_006712572 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220281_at AI632015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI632015 /FEA=EST /DB_XREF=gi:4683345 /DB_XREF=est:wa38g11.x1 /CLONE=IMAGE:2300420 /UG=Hs.123116 solute carrier family 12 (sodiumpotassiumchloride transporters), member 1 /FL=gb:U58130.1 gb:NM_000338.1 AI632015 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 SLC12A1 6557 NM_000338 /// NM_001184832 /// XM_005254605 /// XM_005254606 /// XM_006720656 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0007588 // excretion // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from sequence or structural similarity /// 0048878 // chemical homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008511 // sodium:potassium:chloride symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation 220282_at NM_024557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024557.1 /DEF=Homo sapiens hypothetical protein FLJ11608 (FLJ11608), mRNA. /FEA=mRNA /GEN=FLJ11608 /PROD=hypothetical protein FLJ11608 /DB_XREF=gi:13375722 /UG=Hs.12315 hypothetical protein FLJ11608 /FL=gb:NM_024557.1 NM_024557 RIC3 acetylcholine receptor chaperone RIC3 79608 NM_001135109 /// NM_001206671 /// NM_001206672 /// NM_024557 /// NR_045405 /// XM_006718316 /// XM_006718317 /// XM_006718318 /// XM_006718319 /// XM_006718320 /// XM_006718321 /// XM_006718322 /// XR_428848 /// XR_428849 /// XR_428850 /// XR_428851 0006457 // protein folding // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // inferred from electronic annotation /// 0043623 // cellular protein complex assembly // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0033130 // acetylcholine receptor binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 220283_at NM_024746 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024746.1 /DEF=Homo sapiens hypothetical protein FLJ13840 (FLJ13840), mRNA. /FEA=mRNA /GEN=FLJ13840 /PROD=hypothetical protein FLJ13840 /DB_XREF=gi:13376071 /UG=Hs.123515 hypothetical protein FLJ13840 /FL=gb:NM_024746.1 NM_024746 HHIP-like 2 HHIPL2 79802 NM_024746 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016901 // oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation 220284_at NM_014419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014419.1 /DEF=Homo sapiens soggy-1 gene (SGY-1), mRNA. /FEA=mRNA /GEN=SGY-1 /PROD=soggy-1 gene /DB_XREF=gi:7657553 /UG=Hs.124021 soggy-1 gene /FL=gb:AF177398.1 gb:NM_014419.1 NM_014419 dickkopf-like 1 DKKL1 27120 NM_001197301 /// NM_001197302 /// NM_014419 /// XM_005258742 /// XM_006723142 /// XM_006723143 /// XM_006723144 /// XM_006723145 0007165 // signal transduction // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220285_at NM_016014 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016014.1 /DEF=Homo sapiens CGI-67 protein (LOC51104), mRNA. /FEA=mRNA /GEN=LOC51104 /PROD=CGI-67 protein /DB_XREF=gi:7705780 /UG=Hs.124831 CGI-67 protein /FL=gb:AF151825.1 gb:NM_016014.1 NM_016014 abhydrolase domain containing 17B ABHD17B 51104 NM_001025780 /// NM_016014 /// XM_006717134 /// XM_006717135 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220286_at NM_017762 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017762.1 /DEF=Homo sapiens hypothetical protein FLJ20313 (FLJ20313), mRNA. /FEA=mRNA /GEN=FLJ20313 /PROD=hypothetical protein FLJ20313 /DB_XREF=gi:8923296 /UG=Hs.126721 hypothetical protein FLJ20313 /FL=gb:NM_017762.1 NM_017762 myotubularin related protein 10 MTMR10 54893 NM_017762 /// XM_005254507 /// XM_005254508 /// XM_006720588 /// XM_006725545 /// XM_006725546 /// XM_006725547 /// XR_429458 /// XR_430868 0016311 // dephosphorylation // inferred from electronic annotation 0016791 // phosphatase activity // inferred from electronic annotation 220287_at NM_020249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020249.1 /DEF=Homo sapiens disintegrin metalloproteinase with thrombospondin repeats (ADAMTS9), mRNA. /FEA=mRNA /GEN=ADAMTS9 /PROD=a disintegrin and metalloproteinase withthrombospondin motifs-9 preproprotein /DB_XREF=gi:9910121 /UG=Hs.126855 disintegrin metalloproteinase with thrombospondin repeats /FL=gb:AF261918.1 gb:NM_020249.1 NM_020249 ADAM metallopeptidase with thrombospondin type 1 motif, 9 ADAMTS9 56999 NM_182920 /// XM_005265329 /// XR_245151 0006508 // proteolysis // inferred from direct assay /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220288_at NM_016239 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016239.1 /DEF=Homo sapiens myosin XV (MYO15), mRNA. /FEA=mRNA /GEN=MYO15 /PROD=myosin XV /DB_XREF=gi:7705900 /UG=Hs.127561 myosin XV /FL=gb:AF144094.1 gb:NM_016239.1 NM_016239 myosin XVA MYO15A 51168 NM_016239 /// XM_005256675 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 220289_s_at NM_017977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017977.1 /DEF=Homo sapiens hypothetical protein FLJ10040 (FLJ10040), mRNA. /FEA=mRNA /GEN=FLJ10040 /PROD=hypothetical protein FLJ10040 /DB_XREF=gi:8922199 /UG=Hs.128738 hypothetical protein FLJ10040 /FL=gb:NM_017977.1 NM_017977 absent in melanoma 1-like AIM1L 55057 NM_001039775 /// NM_017977 /// XM_005245918 220290_at NM_017977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017977.1 /DEF=Homo sapiens hypothetical protein FLJ10040 (FLJ10040), mRNA. /FEA=mRNA /GEN=FLJ10040 /PROD=hypothetical protein FLJ10040 /DB_XREF=gi:8922199 /UG=Hs.128738 hypothetical protein FLJ10040 /FL=gb:NM_017977.1 NM_017977 absent in melanoma 1-like AIM1L 55057 NM_001039775 /// NM_017977 /// XM_005245918 220291_at NM_017711 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017711.1 /DEF=Homo sapiens hypothetical protein FLJ20207 (FLJ20207), mRNA. /FEA=mRNA /GEN=FLJ20207 /PROD=hypothetical protein FLJ20207 /DB_XREF=gi:8923195 /UG=Hs.129014 hypothetical protein FLJ20207 /FL=gb:AB048363.1 gb:NM_017711.1 NM_017711 glycerophosphodiester phosphodiesterase domain containing 2 GDPD2 54857 NM_001171191 /// NM_001171192 /// NM_001171193 /// NM_017711 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047394 // glycerophosphoinositol inositolphosphodiesterase activity // inferred from electronic annotation 220292_at NM_024340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024340.1 /DEF=Homo sapiens hypothetical protein MGC4179 (MGC4179), mRNA. /FEA=mRNA /GEN=MGC4179 /PROD=hypothetical protein MGC4179 /DB_XREF=gi:13236590 /UG=Hs.129369 hypothetical protein MGC4179 /FL=gb:BC002859.1 gb:NM_024340.1 NM_024340 zinc finger and SCAN domain containing 32 ZSCAN32 54925 NM_001284527 /// NM_001284528 /// NM_001284529 /// NM_017810 /// XM_005255402 /// XM_005255403 /// XM_005255404 /// XM_005255406 /// XM_006720901 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220293_at NM_024764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024764.1 /DEF=Homo sapiens hypothetical protein FLJ14298 (FLJ14298), mRNA. /FEA=mRNA /GEN=FLJ14298 /PROD=hypothetical protein FLJ14298 /DB_XREF=gi:13376104 /UG=Hs.131755 hypothetical protein FLJ14298 /FL=gb:NM_024764.1 NM_024764 catsper channel auxiliary subunit beta CATSPERB 79820 NM_024764 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0035036 // sperm-egg recognition // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036128 // CatSper complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 220294_at NM_014379 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014379.1 /DEF=Homo sapiens neuronal potassium channel alpha subunit (KV8.1), mRNA. /FEA=mRNA /GEN=KV8.1 /PROD=neuronal potassium channel alpha subunit /DB_XREF=gi:7657288 /UG=Hs.13285 neuronal potassium channel alpha subunit /FL=gb:AF167082.2 gb:NM_014379.1 NM_014379 potassium channel, subfamily V, member 1 KCNV1 27012 NM_014379 /// XM_005250866 /// XM_005250867 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0015459 // potassium channel regulator activity // traceable author statement 220295_x_at NM_017779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017779.1 /DEF=Homo sapiens hypothetical protein FLJ20354 (FLJ20354), mRNA. /FEA=mRNA /GEN=FLJ20354 /PROD=hypothetical protein FLJ20354 /DB_XREF=gi:8923327 /UG=Hs.133260 hypothetical protein FLJ20354 /FL=gb:NM_017779.1 NM_017779 DEP domain containing 1 DEPDC1 55635 NM_001114120 /// NM_017779 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220296_at NM_024564 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024564.1 /DEF=Homo sapiens hypothetical protein FLJ11715 (FLJ11715), mRNA. /FEA=mRNA /GEN=FLJ11715 /PROD=hypothetical protein FLJ11715 /DB_XREF=gi:13375732 /UG=Hs.13785 hypothetical protein FLJ11715 /FL=gb:NM_024564.1 NM_024564 220297_at NM_018167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018167.1 /DEF=Homo sapiens hypothetical protein FLJ10648 (FLJ10648), mRNA. /FEA=mRNA /GEN=FLJ10648 /PROD=hypothetical protein FLJ10648 /DB_XREF=gi:8922568 /UG=Hs.13809 hypothetical protein FLJ10648 /FL=gb:NM_018167.1 NM_018167 BTB (POZ) domain containing 7 BTBD7 55727 NM_001002860 /// NM_001289133 /// NM_018167 /// XM_006720195 /// XM_006725166 0007275 // multicellular organismal development // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 220298_s_at NM_019073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019073.1 /DEF=Homo sapiens hypothetical protein (FLJ10007), mRNA. /FEA=mRNA /GEN=FLJ10007 /PROD=hypothetical protein /DB_XREF=gi:9506602 /UG=Hs.143251 hypothetical protein /FL=gb:NM_019073.1 NM_019073 spermatogenesis associated 6 SPATA6 54558 NM_001286238 /// NM_001286239 /// NM_019073 /// XM_005270948 /// XM_006710699 /// XM_006710700 /// XM_006710701 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 220299_at NM_019073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019073.1 /DEF=Homo sapiens hypothetical protein (FLJ10007), mRNA. /FEA=mRNA /GEN=FLJ10007 /PROD=hypothetical protein /DB_XREF=gi:9506602 /UG=Hs.143251 hypothetical protein /FL=gb:NM_019073.1 NM_019073 spermatogenesis associated 6 SPATA6 54558 NM_001286238 /// NM_001286239 /// NM_019073 /// XM_005270948 /// XM_006710699 /// XM_006710700 /// XM_006710701 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 220300_at NM_017790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017790.1 /DEF=Homo sapiens homolog of mouse C2PA (FLJ20370), mRNA. /FEA=mRNA /GEN=FLJ20370 /PROD=homolog of mouse C2PA /DB_XREF=gi:8923347 /UG=Hs.144840 homolog of mouse C2PA /FL=gb:NM_017790.1 NM_017790 regulator of G-protein signaling 3 RGS3 5998 NM_001276260 /// NM_001276261 /// NM_001276262 /// NM_001282922 /// NM_001282923 /// NM_017790 /// NM_130795 /// NM_134427 /// NM_144488 /// NM_144489 /// XM_006717219 /// XM_006717220 /// XM_006717221 /// XM_006717222 /// XM_006717223 /// XM_006717224 /// XM_006717225 /// XM_006717226 /// XM_006717227 /// XM_006717228 /// XM_006717229 /// XM_006717230 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 220301_at NM_024781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024781.1 /DEF=Homo sapiens hypothetical protein FLJ23594 (FLJ23594), mRNA. /FEA=mRNA /GEN=FLJ23594 /PROD=hypothetical protein FLJ23594 /DB_XREF=gi:13376139 /UG=Hs.146025 hypothetical protein FLJ23594 /FL=gb:NM_024781.1 NM_024781 coiled-coil domain containing 102B CCDC102B 79839 NM_001093729 /// NM_024781 /// XM_005266764 /// XM_005266765 /// XM_005266768 /// XM_006722542 /// XM_006722543 /// XM_006722544 /// XM_006722545 /// XM_006722546 /// XR_430083 /// XR_430084 /// XR_430085 220302_at NM_005906 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005906.2 /DEF=Homo sapiens male germ cell-associated kinase (MAK), mRNA. /FEA=mRNA /GEN=MAK /PROD=male germ cell-associated kinase /DB_XREF=gi:13699865 /UG=Hs.148496 male germ cell-associated kinase /FL=gb:NM_005906.2 NM_005906 male germ cell-associated kinase MAK 4117 NM_001242385 /// NM_001242957 /// NM_005906 /// XM_006715098 /// XR_427831 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072686 // mitotic spindle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220303_at NM_024791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024791.1 /DEF=Homo sapiens hypothetical protein FLJ22756 (FLJ22756), mRNA. /FEA=mRNA /GEN=FLJ22756 /PROD=hypothetical protein FLJ22756 /DB_XREF=gi:13376159 /UG=Hs.154088 hypothetical protein FLJ22756 /FL=gb:NM_024791.1 NM_024791 PDZ domain containing 3 PDZD3 79849 NM_001168468 /// NM_024791 /// NR_033122 /// XM_005271678 /// XM_006718914 0006811 // ion transport // non-traceable author statement /// 0006833 // water transport // non-traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred by curator /// 0009636 // response to toxic substance // traceable author statement /// 0019934 // cGMP-mediated signaling // non-traceable author statement /// 0030827 // negative regulation of cGMP biosynthetic process // traceable author statement /// 0031283 // negative regulation of guanylate cyclase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0035003 // subapical complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0030251 // guanylate cyclase inhibitor activity // inferred from direct assay 220304_s_at NM_019098 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019098.1 /DEF=Homo sapiens cyclic nucleotide gated channel beta 3 (CNGB3), mRNA. /FEA=mRNA /GEN=CNGB3 /PROD=cyclic nucleotide gated channel beta 3 /DB_XREF=gi:9506498 /UG=Hs.154433 cyclic nucleotide gated channel beta 3 /FL=gb:AF228520.1 gb:AF272900.1 gb:NM_019098.1 NM_019098 cyclic nucleotide gated channel beta 3 CNGB3 54714 NM_019098 /// XM_006716593 0006810 // transport // non-traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // not recorded /// 0042391 // regulation of membrane potential // not recorded /// 0050896 // response to stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 1902495 // transmembrane transporter complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005222 // intracellular cAMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // not recorded /// 0005223 // intracellular cGMP activated cation channel activity // inferred from direct assay /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0030553 // cGMP binding // not recorded /// 0030553 // cGMP binding // inferred from direct assay 220305_at NM_024030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024030.1 /DEF=Homo sapiens hypothetical protein MGC3260 (MGC3260), mRNA. /FEA=mRNA /GEN=MGC3260 /PROD=hypothetical protein MGC3260 /DB_XREF=gi:13128977 /UG=Hs.15514 hypothetical protein MGC3260 /FL=gb:BC000073.1 gb:NM_024030.1 NM_024030 mitochondrial antiviral signaling protein MAVS 57506 NM_001206491 /// NM_020746 /// NR_037921 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002218 // activation of innate immune response // inferred from mutant phenotype /// 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred from mutant phenotype /// 0032728 // positive regulation of interferon-beta production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from direct assay /// 0039529 // RIG-I signaling pathway // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from direct assay /// 0071360 // cellular response to exogenous dsRNA // inferred from mutant phenotype /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // inferred from direct assay /// 0071660 // positive regulation of IP-10 production // inferred from direct assay /// 1900063 // regulation of peroxisome organization // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050700 // CARD domain binding // inferred from physical interaction 220306_at NM_017709 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017709.1 /DEF=Homo sapiens hypothetical protein FLJ20202 (FLJ20202), mRNA. /FEA=mRNA /GEN=FLJ20202 /PROD=hypothetical protein FLJ20202 /DB_XREF=gi:8923191 /UG=Hs.155556 hypothetical protein FLJ20202 /FL=gb:NM_017709.1 NM_017709 family with sequence similarity 46, member C FAM46C 54855 NM_017709 220307_at NM_016382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016382.1 /DEF=Homo sapiens natural killer cell receptor 2B4 (CD244), mRNA. /FEA=mRNA /GEN=CD244 /PROD=natural killer cell receptor 2B4 /DB_XREF=gi:7706528 /UG=Hs.157872 natural killer cell receptor 2B4 /FL=gb:AF242540.1 gb:AF105261.1 gb:AF145782.1 gb:AF107761.2 gb:AF117711.1 gb:NM_016382.1 NM_016382 CD244 molecule, natural killer cell receptor 2B4 CD244 51744 NM_001166663 /// NM_001166664 /// NM_016382 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220308_at NM_012337 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012337.1 /DEF=Homo sapiens nasopharyngeal epithelium specific protein 1 (NESG1), mRNA. /FEA=mRNA /GEN=NESG1 /PROD=nasopharyngeal epithelium specific protein 1 /DB_XREF=gi:6912525 /UG=Hs.158450 nasopharyngeal epithelium specific protein 1 /FL=gb:AF094758.1 gb:NM_012337.1 NM_012337 coiled-coil domain containing 19 CCDC19 25790 NM_012337 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 220309_at NM_017904 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017904.1 /DEF=Homo sapiens hypothetical protein FLJ20619 (FLJ20619), mRNA. /FEA=mRNA /GEN=FLJ20619 /PROD=hypothetical protein FLJ20619 /DB_XREF=gi:8923572 /UG=Hs.16230 hypothetical protein FLJ20619 /FL=gb:NM_017904.1 NM_017904 tetratricopeptide repeat domain 22 TTC22 55001 NM_001114108 /// NM_017904 0005515 // protein binding // inferred from electronic annotation 220310_at NM_024803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024803.1 /DEF=Homo sapiens hypothetical protein FLJ21665 (FLJ21665), mRNA. /FEA=mRNA /GEN=FLJ21665 /PROD=hypothetical protein FLJ21665 /DB_XREF=gi:13376180 /UG=Hs.163079 hypothetical protein FLJ21665 /FL=gb:NM_024803.1 NM_024803 tubulin, alpha-like 3 TUBAL3 79861 NM_001171864 /// NM_024803 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 220311_at NM_013240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013240.1 /DEF=Homo sapiens putative N6-DNA-methyltransferase (N6AMT1), mRNA. /FEA=mRNA /GEN=N6AMT1 /PROD=putative N6-DNA-methyltransferase /DB_XREF=gi:7019462 /UG=Hs.163846 putative N6-DNA-methyltransferase /FL=gb:AF139682.1 gb:NM_013240.1 NM_013240 N-6 adenine-specific DNA methyltransferase 1 (putative) N6AMT1 29104 NM_013240 /// NM_182749 /// NR_047510 0006479 // protein methylation // inferred from direct assay /// 0006479 // protein methylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 220312_at NM_017708 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017708.1 /DEF=Homo sapiens hypothetical protein FLJ20200 (FLJ20200), mRNA. /FEA=mRNA /GEN=FLJ20200 /PROD=hypothetical protein FLJ20200 /DB_XREF=gi:8923189 /UG=Hs.165803 hypothetical protein FLJ20200 /FL=gb:NM_017708.1 NM_017708 family with sequence similarity 83, member E FAM83E 54854 NM_017708 /// XM_005259019 220313_at NM_022049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022049.1 /DEF=Homo sapiens G-protein coupled receptor 88 (GPR88), mRNA. /FEA=mRNA /GEN=GPR88 /PROD=G-protein coupled receptor 88 /DB_XREF=gi:11545752 /UG=Hs.170053 G-protein coupled receptor 88 /FL=gb:AB042410.1 gb:NM_022049.1 NM_022049 G protein-coupled receptor 88 GPR88 54112 NM_022049 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220314_at NM_016153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016153.1 /DEF=Homo sapiens LW-1 (LW-1), mRNA. /FEA=mRNA /GEN=LW-1 /PROD=LW-1 /DB_XREF=gi:7706602 /UG=Hs.179756 LW-1 /FL=gb:AF139980.1 gb:NM_016153.1 NM_016153 heat shock transcription factor family, X linked 1 /// heat shock transcription factor family, X linked 2 HSFX1 /// HSFX2 100130086 /// 100506164 NM_001164415 /// NM_016153 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220315_at NM_020367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020367.1 /DEF=Homo sapiens chromosome 12 open reading frame 6 (C12ORF6), mRNA. /FEA=mRNA /GEN=C12ORF6 /PROD=chromosome 12 open reading frame 6 /DB_XREF=gi:9966836 /UG=Hs.188189 chromosome 12 open reading frame 6 /FL=gb:AF263540.1 gb:NM_020367.1 NM_020367 poly (ADP-ribose) polymerase family, member 11 PARP11 57097 NM_001286521 /// NM_001286522 /// NM_020367 /// NR_104461 /// XM_005253710 /// XM_005253711 /// XM_005253714 /// XM_006718987 0008152 // metabolic process // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220316_at NM_022123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022123.1 /DEF=Homo sapiens basic-helix-loop-helix-PAS protein (NPAS3), mRNA. /FEA=mRNA /GEN=NPAS3 /PROD=basic-helix-loop-helix-PAS protein /DB_XREF=gi:11545846 /UG=Hs.190125 basic-helix-loop-helix-PAS protein /FL=gb:AF164438.1 gb:NM_022123.1 gb:AB054575.1 NM_022123 neuronal PAS domain protein 3 NPAS3 64067 NM_001164749 /// NM_001165893 /// NM_022123 /// NM_173159 /// XM_005267991 /// XM_005267992 /// XM_005267993 0001964 // startle response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220317_at NM_004744 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004744.1 /DEF=Homo sapiens lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT), mRNA. /FEA=mRNA /GEN=LRAT /PROD=lecithin retinol acyltransferase(phosphatidylcholine--retinol O-acyltransferase) /DB_XREF=gi:4758683 /UG=Hs.194708 lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) /FL=gb:AF071510.1 gb:NM_004744.1 NM_004744 uncharacterized LOC101927965 /// lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) LOC101927965 /// LRAT 9227 /// 101927965 NM_004744 /// XM_006714412 /// XR_244741 /// XR_249685 /// XR_251680 0001523 // retinoid metabolic process // traceable author statement /// 0006776 // vitamin A metabolic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0001972 // retinoic acid binding // inferred from electronic annotation /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0019841 // retinol binding // inferred from electronic annotation /// 0047173 // phosphatidylcholine-retinol O-acyltransferase activity // inferred from electronic annotation 220318_at NM_017957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017957.1 /DEF=Homo sapiens epsin 3 (FLJ20778), mRNA. /FEA=mRNA /GEN=FLJ20778 /PROD=epsin 3 /DB_XREF=gi:8923677 /UG=Hs.199480 epsin 3 /FL=gb:AF324241.1 gb:NM_017957.1 NM_017957 epsin 3 EPN3 55040 NM_017957 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 220319_s_at NM_013262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013262.2 /DEF=Homo sapiens myosin regulatory light chain interacting protein (MIR), mRNA. /FEA=mRNA /GEN=MIR /PROD=myosin regulatory light chain interactingprotein /DB_XREF=gi:10880121 /UG=Hs.20072 myosin regulatory light chain interacting protein /FL=gb:AF187016.2 gb:NM_013262.2 gb:BC002860.1 NM_013262 myosin regulatory light chain interacting protein MYLIP 29116 NM_013262 /// XM_005249032 /// XM_005249033 0006928 // cellular component movement // inferred from mutant phenotype /// 0007399 // nervous system development // inferred from mutant phenotype /// 0010989 // negative regulation of low-density lipoprotein particle clearance // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032803 // regulation of low-density lipoprotein particle receptor catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220320_at NM_024872 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024872.1 /DEF=Homo sapiens hypothetical protein FLJ22570 (FLJ22570), mRNA. /FEA=mRNA /GEN=FLJ22570 /PROD=hypothetical protein FLJ22570 /DB_XREF=gi:13376307 /UG=Hs.205450 hypothetical protein FLJ22570 /FL=gb:NM_024872.1 NM_024872 docking protein 3 DOK3 79930 NM_001144875 /// NM_001144876 /// NM_024872 /// XM_005265984 /// XM_005265985 /// XM_005265987 /// XM_006714920 0007265 // Ras protein signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 220321_s_at NM_024584 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024584.1 /DEF=Homo sapiens hypothetical protein FLJ13646 (FLJ13646), mRNA. /FEA=mRNA /GEN=FLJ13646 /PROD=hypothetical protein FLJ13646 /DB_XREF=gi:13375767 /UG=Hs.21081 hypothetical protein FLJ13646 /FL=gb:NM_024584.1 NM_024584 coiled-coil domain containing 121 CCDC121 79635 NM_001142682 /// NM_001142683 /// NM_024584 /// XM_005264560 220322_at NM_019618 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019618.1 /DEF=Homo sapiens interleukin-1 homolog 1 (IL-1H1), mRNA. /FEA=mRNA /GEN=IL-1H1 /PROD=interleukin-1 homolog 1 /DB_XREF=gi:9665233 /UG=Hs.211238 interleukin-1 homolog 1 /FL=gb:AF206696.1 gb:AF200492.1 gb:NM_019618.1 NM_019618 interleukin 36, gamma IL36G 56300 NM_001278568 /// NM_019618 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation 220323_at NM_024877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024877.1 /DEF=Homo sapiens hypothetical protein FLJ13265 (FLJ13265), mRNA. /FEA=mRNA /GEN=FLJ13265 /PROD=hypothetical protein FLJ13265 /DB_XREF=gi:13376317 /UG=Hs.212640 hypothetical protein FLJ13265 /FL=gb:NM_024877.1 NM_024877 cyclin N-terminal domain containing 2 CNTD2 79935 NM_024877 /// XM_006723395 /// XM_006723396 /// XR_430212 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0019901 // protein kinase binding // inferred from electronic annotation 220324_at NM_024882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024882.1 /DEF=Homo sapiens hypothetical protein FLJ13189 (FLJ13189), mRNA. /FEA=mRNA /GEN=FLJ13189 /PROD=hypothetical protein FLJ13189 /DB_XREF=gi:13376326 /UG=Hs.216312 hypothetical protein FLJ13189 /FL=gb:NM_024882.1 NM_024882 long intergenic non-protein coding RNA 472 LINC00472 79940 NR_026807 /// NR_121612 /// NR_121613 /// NR_121614 /// XR_426058 /// XR_427982 /// XR_432036 220325_at NM_024885 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024885.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, Q (TAF2Q), mRNA. /FEA=mRNA /GEN=TAF2Q /PROD=hypothetical protein FLJ23157 /DB_XREF=gi:13376332 /UG=Hs.223806 hypothetical protein FLJ23157 /FL=gb:NM_024885.1 NM_024885 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa TAF7L 54457 NM_001168474 /// NM_024885 /// XM_005262151 /// XM_005262152 /// XM_006724664 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 220326_s_at NM_018071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018071.1 /DEF=Homo sapiens hypothetical protein FLJ10357 (FLJ10357), mRNA. /FEA=mRNA /GEN=FLJ10357 /PROD=hypothetical protein FLJ10357 /DB_XREF=gi:8922375 /UG=Hs.22451 hypothetical protein FLJ10357 /FL=gb:NM_018071.1 NM_018071 Rho guanine nucleotide exchange factor (GEF) 40 ARHGEF40 55701 NM_001278529 /// NM_001278530 /// NM_018071 /// XM_005267844 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 220327_at NM_016206 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016206.1 /DEF=Homo sapiens colon carcinoma related protein (LOC51159), mRNA. /FEA=mRNA /GEN=LOC51159 /PROD=colon carcinoma related protein /DB_XREF=gi:7705882 /UG=Hs.23142 colon carcinoma related protein /FL=gb:AF099505.1 gb:NM_016206.1 NM_016206 vestigial-like family member 3 VGLL3 389136 NM_016206 /// XM_005264752 /// XM_005264753 /// XM_006713138 /// XM_006713139 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 220328_at NM_024947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024947.1 /DEF=Homo sapiens hypothetical protein FLJ12729 (FLJ12729), mRNA. /FEA=mRNA /GEN=FLJ12729 /PROD=hypothetical protein FLJ12729 /DB_XREF=gi:13489102 /UG=Hs.231977 hypothetical protein FLJ12729 /FL=gb:NM_024947.1 NM_024947 polyhomeotic homolog 3 (Drosophila) PHC3 80012 NM_024947 /// XM_005247789 /// XM_005247790 /// XM_005247791 /// XM_005247793 /// XM_006713753 /// XM_006713754 /// XM_006713755 /// XM_006713756 /// XM_006713757 /// XR_241509 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220329_s_at NM_017909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017909.1 /DEF=Homo sapiens hypothetical protein FLJ20627 (FLJ20627), mRNA. /FEA=mRNA /GEN=FLJ20627 /PROD=hypothetical protein FLJ20627 /DB_XREF=gi:8923583 /UG=Hs.238270 hypothetical protein FLJ20627 /FL=gb:NM_017909.1 NM_017909 required for meiotic nuclear division 1 homolog (S. cerevisiae) RMND1 55005 NM_001271937 /// NM_017909 /// XM_005267040 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay 220330_s_at NM_022136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022136.1 /DEF=Homo sapiens SAM domain, SH3 domain and nuclear localisation signals, 1 (SAMSN1), mRNA. /FEA=mRNA /GEN=SAMSN1 /PROD=SAM domain, SH3 domain and nuclear localisationsignals, 1 /DB_XREF=gi:11545870 /UG=Hs.24633 SAM domain, SH3 domain and nuclear localisation signals, 1 /FL=gb:AF222927.1 gb:NM_022136.1 NM_022136 SAM domain, SH3 domain and nuclear localization signals 1 SAMSN1 64092 NM_001256370 /// NM_001286523 /// NM_022136 0002820 // negative regulation of adaptive immune response // inferred from sequence or structural similarity /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0001784 // phosphotyrosine binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220331_at NM_006668 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006668.1 /DEF=Homo sapiens cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) (CYP46), mRNA. /FEA=mRNA /GEN=CYP46 /PROD=cytochrome P450, subfamily 46 (cholesterol24-hydroxylase) /DB_XREF=gi:5729795 /UG=Hs.25121 cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) /FL=gb:AF094480.1 gb:NM_006668.1 NM_006668 cytochrome P450, family 46, subfamily A, polypeptide 1 CYP46A1 10858 NM_006668 /// XM_005267274 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006707 // cholesterol catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0033781 // cholesterol 24-hydroxylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220332_at NM_006580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006580.1 /DEF=Homo sapiens claudin 16 (CLDN16), mRNA. /FEA=mRNA /GEN=CLDN16 /PROD=claudin 16 /DB_XREF=gi:5729969 /UG=Hs.251391 claudin 16 /FL=gb:AF152101.1 gb:NM_006580.1 NM_006580 claudin 16 CLDN16 10686 NM_006580 /// XM_006713479 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006875 // cellular metal ion homeostasis // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015693 // magnesium ion transport // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015095 // magnesium ion transmembrane transporter activity // traceable author statement /// 0042802 // identical protein binding // inferred from sequence or structural similarity 220333_at NM_017705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017705.1 /DEF=Homo sapiens hypothetical protein FLJ20190 (FLJ20190), mRNA. /FEA=mRNA /GEN=FLJ20190 /PROD=hypothetical protein FLJ20190 /DB_XREF=gi:8923182 /UG=Hs.257511 hypothetical protein FLJ20190 /FL=gb:NM_017705.1 NM_017705 progestin and adipoQ receptor family member V PAQR5 54852 NM_001104554 /// NM_017705 /// XM_005254494 /// XM_005254495 /// XM_005254496 /// XM_006720583 /// XM_006720584 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded /// 0005496 // steroid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 220334_at NM_012419 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012419.2 /DEF=Homo sapiens regulator of G-protein signalling 17 (RGS17), mRNA. /FEA=mRNA /GEN=RGS17 /PROD=regulator of G-protein signalling 17 /DB_XREF=gi:8394185 /UG=Hs.268562 regulator of G-protein signalling 17 /FL=gb:AF202257.2 gb:NM_012419.2 NM_012419 regulator of G-protein signaling 17 RGS17 26575 NM_012419 /// XM_006715460 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded 220335_x_at NM_024922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024922.1 /DEF=Homo sapiens hypothetical protein FLJ21736 (FLJ21736), mRNA. /FEA=mRNA /GEN=FLJ21736 /PROD=hypothetical protein FLJ21736 /DB_XREF=gi:13376395 /UG=Hs.268700 hypothetical protein FLJ21736 /FL=gb:NM_024922.1 NM_024922 carboxylesterase 3 CES3 23491 NM_001185176 /// NM_001185177 /// NM_012122 /// NM_024922 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0052689 // carboxylic ester hydrolase activity // inferred from electronic annotation 220336_s_at AB043821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB043821.1 /DEF=Homo sapiens GPVI mRNA for platelet glycoprotein VI-3, complete cds. /FEA=mRNA /GEN=GPVI /PROD=platelet glycoprotein VI-3 /DB_XREF=gi:9955913 /UG=Hs.272216 glycoprotein VI (platelet) /FL=gb:AB035073.1 gb:NM_016363.1 gb:AB043819.1 gb:AB043821.1 AB043821 glycoprotein VI (platelet) GP6 51206 NM_001083899 /// NM_001256017 /// NM_016363 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement 220337_at NM_021257 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021257.1 /DEF=Homo sapiens neuroglobin (NGB), mRNA. /FEA=mRNA /GEN=NGB /PROD=neuroglobin /DB_XREF=gi:10864064 /UG=Hs.274363 neuroglobin /FL=gb:NM_021257.1 NM_021257 neuroglobin NGB 58157 NM_021257 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015671 // oxygen transport // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005833 // hemoglobin complex // non-traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation 0005344 // oxygen transporter activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220338_at NM_018037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018037.1 /DEF=Homo sapiens hypothetical protein FLJ10244 (FLJ10244), mRNA. /FEA=mRNA /GEN=FLJ10244 /PROD=hypothetical protein FLJ10244 /DB_XREF=gi:8922306 /UG=Hs.274419 hypothetical protein FLJ10244 /FL=gb:NM_018037.1 NM_018037 Ral GEF with PH domain and SH3 binding motif 2 RALGPS2 55103 NM_001286247 /// NM_018037 /// NM_152663 /// XM_006711409 /// XM_006711410 /// XM_006711411 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 220339_s_at NM_012467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012467.1 /DEF=Homo sapiens tryptase gamma 1 (TPSG1), mRNA. /FEA=mRNA /GEN=TPSG1 /PROD=transmembrane tryptase preproprotein /DB_XREF=gi:6912727 /UG=Hs.278275 tryptase gamma 1 /FL=gb:AF175522.1 gb:NM_012467.1 NM_012467 tryptase gamma 1 TPSG1 25823 NM_012467 /// XM_006720875 /// XM_006720876 0006508 // proteolysis // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 220340_at NM_024935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024935.1 /DEF=Homo sapiens hypothetical protein FLJ13687 (FLJ13687), mRNA. /FEA=mRNA /GEN=FLJ13687 /PROD=hypothetical protein FLJ13687 /DB_XREF=gi:13376407 /UG=Hs.278850 hypothetical protein FLJ13687 /FL=gb:NM_024935.1 NM_024935 growth regulation by estrogen in breast cancer-like GREB1L 80000 NM_001142966 /// NM_024935 /// XM_006722547 /// XM_006722548 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220341_s_at NM_016175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016175.1 /DEF=Homo sapiens truncated calcium binding protein (LOC51149), mRNA. /FEA=mRNA /GEN=LOC51149 /PROD=truncated calcium binding protein /DB_XREF=gi:7705864 /UG=Hs.279891 truncated calcium binding protein /FL=gb:BC002739.1 gb:AF153685.1 gb:NM_016175.1 NM_016175 chromosome 5 open reading frame 45 C5orf45 51149 NM_001017987 /// NM_001018061 /// NM_001018062 /// NM_016175 220342_x_at NM_017992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017992.1 /DEF=Homo sapiens hypothetical protein FLJ10083 (FLJ10083), mRNA. /FEA=mRNA /GEN=FLJ10083 /PROD=hypothetical protein FLJ10083 /DB_XREF=gi:8922223 /UG=Hs.279951 hypothetical protein FLJ10083 /FL=gb:NM_017992.1 NM_017992 ER degradation enhancer, mannosidase alpha-like 3 EDEM3 80267 NM_025191 /// XM_005245499 0006457 // protein folding // traceable author statement /// 0006516 // glycoprotein catabolic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0004569 // glycoprotein endo-alpha-1,2-mannosidase activity // inferred from electronic annotation /// 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220343_at NM_018945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018945.1 /DEF=Homo sapiens phosphodiesterase 7B (PDE7B), mRNA. /FEA=mRNA /GEN=PDE7B /PROD=phosphodiesterase 7B /DB_XREF=gi:9506958 /UG=Hs.283016 phosphodiesterase 7B /FL=gb:AB038040.1 gb:NM_018945.1 NM_018945 phosphodiesterase 7B PDE7B 27115 NM_018945 /// XM_005266931 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220344_at NM_020643 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020643.1 /DEF=Homo sapiens chromosome 11 open reading frame 16 (C11ORF16), mRNA. /FEA=mRNA /GEN=C11ORF16 /PROD=chromosome 11 open reading frame 16 /DB_XREF=gi:11068140 /UG=Hs.283807 chromosome 11 open reading frame 16 /FL=gb:NM_020643.1 NM_020643 chromosome 11 open reading frame 16 C11orf16 56673 NM_020643 220345_at NM_024993 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024993.1 /DEF=Homo sapiens hypothetical protein FLJ12568 (FLJ12568), mRNA. /FEA=mRNA /GEN=FLJ12568 /PROD=hypothetical protein FLJ12568 /DB_XREF=gi:13376497 /UG=Hs.287534 hypothetical protein FLJ12568 /FL=gb:NM_024993.1 NM_024993 leucine rich repeat transmembrane neuronal 4 LRRTM4 80059 NM_001134745 /// NM_001282924 /// NM_001282928 /// NM_024993 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220346_at NM_025001 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025001.1 /DEF=Homo sapiens hypothetical protein FLJ13105 (FLJ13105), mRNA. /FEA=mRNA /GEN=FLJ13105 /PROD=hypothetical protein FLJ13105 /DB_XREF=gi:13376512 /UG=Hs.287550 hypothetical protein FLJ13105 /FL=gb:NM_025001.1 NM_025001 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like MTHFD2L 441024 NM_001004346 /// NM_001144978 /// XM_005265690 /// XM_005265691 /// XM_005265692 0000105 // histidine biosynthetic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004487 // methylenetetrahydrofolate dehydrogenase (NAD+) activity // not recorded /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220347_at NM_025023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025023.1 /DEF=Homo sapiens hypothetical protein FLJ14069 (FLJ14069), mRNA. /FEA=mRNA /GEN=FLJ14069 /PROD=hypothetical protein FLJ14069 /DB_XREF=gi:13376540 /UG=Hs.287621 hypothetical protein FLJ14069 /FL=gb:NM_025023.1 NM_025023 SMG6 nonsense mediated mRNA decay factor SMG6 23293 NM_001170957 /// NM_001256827 /// NM_001256828 /// NM_001282326 /// NM_017575 /// XM_005256569 /// XM_005256570 /// XM_005256571 /// XM_006721493 /// XM_006721494 /// XM_006721495 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from mutant phenotype /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005697 // telomerase holoenzyme complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // inferred from direct assay /// 0004521 // endoribonuclease activity // inferred from mutant phenotype /// 0004521 // endoribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220348_at NM_025067 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025067.1 /DEF=Homo sapiens hypothetical protein FLJ14106 (FLJ14106), mRNA. /FEA=mRNA /GEN=FLJ14106 /PROD=hypothetical protein FLJ14106 /DB_XREF=gi:13376606 /UG=Hs.287872 hypothetical protein FLJ14106 /FL=gb:NM_025067.1 NM_025067 kelch-like family member 29 KLHL29 114818 NM_025067 /// NM_052920 /// XM_006711929 220349_s_at NM_022759 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022759.1 /DEF=Homo sapiens hypothetical protein FLJ21865 (FLJ21865), mRNA. /FEA=mRNA /GEN=FLJ21865 /PROD=hypothetical protein FLJ21865 /DB_XREF=gi:12232428 /UG=Hs.29288 hypothetical protein FLJ21865 /FL=gb:NM_022759.1 NM_022759 endo-beta-N-acetylglucosaminidase ENGASE 64772 NM_001042573 /// NM_022759 /// XM_006722015 /// XM_006722016 /// XM_006722017 /// XM_006722018 /// XM_006722019 /// XR_429918 /// XR_429919 /// XR_429920 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0033925 // mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity // inferred from electronic annotation 220350_at NM_004234 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004234.3 /DEF=Homo sapiens zinc finger protein homologous to Zfp93 in mouse (ZFP93), mRNA. /FEA=mRNA /GEN=ZFP93 /PROD=zinc finger protein 270 /DB_XREF=gi:12056481 /UG=Hs.298089 zinc finger protein homologous to Zfp93 in mouse /FL=gb:NM_004234.3 NM_004234 zinc finger protein 235 ZNF235 9310 NM_004234 /// XM_005259412 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220351_at NM_016557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016557.1 /DEF=Homo sapiens orphan seven-transmembrane receptor, chemokine related (VSHK1), mRNA. /FEA=mRNA /GEN=VSHK1 /PROD=orphan seven-transmembrane receptor, chemokinerelated /DB_XREF=gi:7706768 /UG=Hs.310512 orphan seven-transmembrane receptor, chemokine related /FL=gb:AF110640.1 gb:NM_016557.1 NM_016557 atypical chemokine receptor 4 ACKR4 51554 NM_016557 /// NM_178445 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019956 // chemokine binding // inferred from electronic annotation 220352_x_at NM_024305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024305.1 /DEF=Homo sapiens hypothetical protein MGC4278 (MGC4278), mRNA. /FEA=mRNA /GEN=MGC4278 /PROD=hypothetical protein MGC4278 /DB_XREF=gi:13236535 /UG=Hs.318780 hypothetical protein MGC4278 /FL=gb:BC002659.1 gb:NM_024305.1 NM_024305 uncharacterized LOC645644 FLJ42627 645644 NR_024492 220353_at NM_018172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018172.1 /DEF=Homo sapiens hypothetical protein FLJ10661 (FLJ10661), mRNA. /FEA=mRNA /GEN=FLJ10661 /PROD=hypothetical protein FLJ10661 /DB_XREF=gi:8922578 /UG=Hs.325173 hypothetical protein FLJ10661 /FL=gb:NM_018172.1 NM_018172 family with sequence similarity 86, member C1 FAM86C1 55199 NM_001099653 /// NM_018172 /// NM_152563 220354_at NM_025266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025266.1 /DEF=Homo sapiens hypothetical protein MGC2780 (MGC2780), mRNA. /FEA=mRNA /GEN=MGC2780 /PROD=hypothetical protein MGC2780 /DB_XREF=gi:13376883 /UG=Hs.326560 hypothetical protein MGC2780 /FL=gb:BC004179.1 gb:NM_025266.1 NM_025266 MCF2L antisense RNA 1 MCF2L-AS1 100289410 NR_034002 220355_s_at NM_018165 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018165.1 /DEF=Homo sapiens hypothetical protein FLJ10645 (FLJ10645), mRNA. /FEA=mRNA /GEN=FLJ10645 /PROD=hypothetical protein FLJ10645 /DB_XREF=gi:8922564 /UG=Hs.44143 polybromo 1 /FL=gb:AF177387.1 gb:NM_018165.1 NM_018165 polybromo 1 PBRM1 55193 NM_018165 /// NM_018313 /// NM_181041 /// NM_181042 /// XM_005265275 /// XM_005265279 /// XM_005265280 /// XM_005265282 /// XM_005265283 /// XM_005265288 /// XM_006713220 /// XM_006713221 /// XM_006713222 /// XM_006713223 /// XM_006713224 /// XM_006713225 /// XM_006713226 /// XM_006713227 /// XM_006713228 /// XM_006713229 /// XM_006713230 /// XM_006713231 /// XM_006713232 /// XM_006713233 /// XM_006713234 0001890 // placenta development // inferred from electronic annotation /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220356_at NM_006587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006587.1 /DEF=Homo sapiens corin (PRSC), mRNA. /FEA=mRNA /GEN=PRSC /PROD=corin /DB_XREF=gi:5729988 /UG=Hs.62794 corin /FL=gb:AF133845.1 gb:NM_006587.1 NM_006587 corin, serine peptidase CORIN 10699 NM_001278585 /// NM_001278586 /// NM_006587 0003050 // regulation of systemic arterial blood pressure by atrial natriuretic peptide // inferred from mutant phenotype /// 0003050 // regulation of systemic arterial blood pressure by atrial natriuretic peptide // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0016486 // peptide hormone processing // inferred from direct assay /// 0035813 // regulation of renal sodium excretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 220357_s_at NM_016276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016276.1 /DEF=Homo sapiens serumglucocorticoid regulated kinase 2 (SGK2), mRNA. /FEA=mRNA /GEN=SGK2 /PROD=serumglucocorticoid regulated kinase 2 /DB_XREF=gi:7706698 /UG=Hs.62863 serumglucocorticoid regulated kinase 2 /FL=gb:AF169034.2 gb:NM_016276.1 NM_016276 serum/glucocorticoid regulated kinase 2 SGK2 10110 NM_001199264 /// NM_016276 /// NM_170693 0001558 // regulation of cell growth // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // non-traceable author statement /// 0017080 // sodium channel regulator activity // traceable author statement 220358_at NM_018664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018664.1 /DEF=Homo sapiens Jun dimerization protein p21SNFT (SNFT), mRNA. /FEA=mRNA /GEN=SNFT /PROD=Jun dimerization protein p21SNFT /DB_XREF=gi:8924245 /UG=Hs.62919 Jun dimerization protein p21SNFT /FL=gb:AF255346.1 gb:NM_018664.1 NM_018664 basic leucine zipper transcription factor, ATF-like 3 BATF3 55509 NM_018664 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220359_s_at NM_016300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016300.1 /DEF=Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD (ARPP-21), mRNA. /FEA=mRNA /GEN=ARPP-21 /PROD=cyclic AMP-regulated phosphoprotein, 21 kD /DB_XREF=gi:10047095 /UG=Hs.7459 cyclic AMP-regulated phosphoprotein, 21 kD /FL=gb:NM_016300.1 gb:AF112220.1 NM_016300 cAMP-regulated phosphoprotein, 21kDa ARPP21 10777 NM_001025068 /// NM_001025069 /// NM_001267616 /// NM_001267617 /// NM_001267618 /// NM_001267619 /// NM_016300 /// NM_198399 /// XM_005264810 /// XM_005264811 /// XM_005264812 /// XM_005264813 /// XM_005264815 /// XM_005264816 /// XM_006712942 /// XM_006712943 /// XM_006712944 /// XM_006712945 0034605 // cellular response to heat // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 220360_at NM_024672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024672.1 /DEF=Homo sapiens hypothetical protein FLJ23320 (FLJ23320), mRNA. /FEA=mRNA /GEN=FLJ23320 /PROD=hypothetical protein FLJ23320 /DB_XREF=gi:13375933 /UG=Hs.85910 hypothetical protein FLJ23320 /FL=gb:NM_024672.1 NM_024672 THAP domain containing 9 THAP9 79725 NM_024672 /// XM_005263220 /// XM_005263221 /// XR_244647 0006310 // DNA recombination // inferred from direct assay /// 0006313 // transposition, DNA-mediated // inferred from direct assay /// 0015074 // DNA integration // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004803 // transposase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220361_at NM_022784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022784.1 /DEF=Homo sapiens hypothetical protein FLJ12476 (FLJ12476), mRNA. /FEA=mRNA /GEN=FLJ12476 /PROD=hypothetical protein FLJ12476 /DB_XREF=gi:12232474 /UG=Hs.88144 hypothetical protein FLJ12476 /FL=gb:NM_022784.1 NM_022784 IQ motif containing H IQCH 64799 NM_001031715 /// NM_001284347 /// NM_001284348 /// NM_001284349 /// NM_022784 0005515 // protein binding // inferred from electronic annotation 220362_at NM_014068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014068.1 /DEF=Homo sapiens SEEK1 protein (SEEK1), mRNA. /FEA=mRNA /GEN=SEEK1 /PROD=SEEK1 protein /DB_XREF=gi:7662660 /UG=Hs.91600 SEEK1 protein /FL=gb:AB031479.1 gb:NM_014068.1 NM_014068 psoriasis susceptibility 1 candidate 1 PSORS1C1 170679 NM_014068 0007155 // cell adhesion // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0030057 // desmosome // inferred from direct assay /// 0030057 // desmosome // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042803 // protein homodimerization activity // inferred from direct assay 220363_s_at NM_022086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022086.1 /DEF=Homo sapiens hypothetical protein FLJ11656 (FLJ11656), mRNA. /FEA=mRNA /GEN=FLJ11656 /PROD=hypothetical protein FLJ11656 /DB_XREF=gi:11545798 /UG=Hs.96560 hypothetical protein FLJ11656 /FL=gb:NM_022086.1 NM_022086 engulfment and cell motility 2 ELMO2 63916 NM_022086 /// NM_133171 /// NM_182764 /// XM_005260496 /// XM_005260497 /// XM_005260498 /// XM_005260499 /// XM_005260500 /// XM_005260501 /// XM_005260502 /// XM_006723854 /// XM_006723855 0006909 // phagocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 220364_at NM_019033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019033.1 /DEF=Homo sapiens hypothetical protein (FLJ11235), mRNA. /FEA=mRNA /GEN=FLJ11235 /PROD=hypothetical protein /DB_XREF=gi:9506642 /UG=Hs.97268 hypothetical protein /FL=gb:NM_019033.1 NM_019033 EPB41L4A antisense RNA 2 (head to head) EPB41L4A-AS2 54508 NR_027706 220365_at NM_018436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018436.1 /DEF=Homo sapiens putative allantoicase (LOC55821), mRNA. /FEA=mRNA /GEN=LOC55821 /PROD=putative allantoicase /DB_XREF=gi:10092654 /UG=Hs.97899 putative allantoicase /FL=gb:NM_018436.1 gb:AF215924.1 NM_018436 allantoicase ALLC 55821 NM_018436 /// NM_199232 /// XM_005263851 /// XM_006711891 0000256 // allantoin catabolic process // inferred from electronic annotation 0004037 // allantoicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220366_at NM_022142 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022142.2 /DEF=Homo sapiens epididymal sperm binding protein 1 (ELSPBP1), mRNA. /FEA=mRNA /GEN=ELSPBP1 /PROD=epididymal sperm binding protein 1 precursor /DB_XREF=gi:12408681 /UG=Hs.104894 epididymal sperm binding protein 1 /FL=gb:NM_022142.2 NM_022142 epididymal sperm binding protein 1 ELSPBP1 64100 NM_022142 /// XM_006723322 0007338 // single fertilization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 220367_s_at NM_024545 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024545.1 /DEF=Homo sapiens hypothetical protein FLJ12761 (FLJ12761), mRNA. /FEA=mRNA /GEN=FLJ12761 /PROD=hypothetical protein FLJ12761 /DB_XREF=gi:13375706 /UG=Hs.10554 hypothetical protein FLJ12761 /FL=gb:NM_024545.1 NM_024545 Sin3A-associated protein, 130kDa SAP130 79595 NM_001145928 /// NM_024545 /// XM_005263767 /// XM_005263768 /// XM_005263769 /// XM_005263770 /// XM_006712748 /// XM_006712749 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 220368_s_at NM_017936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017936.1 /DEF=Homo sapiens hypothetical protein FLJ20707 (FLJ20707), mRNA. /FEA=mRNA /GEN=FLJ20707 /PROD=hypothetical protein FLJ20707 /DB_XREF=gi:8923637 /UG=Hs.109441 hypothetical protein FLJ20707 /FL=gb:NM_017936.1 NM_017936 SMEK homolog 1, suppressor of mek1 (Dictyostelium) SMEK1 55671 NM_001284280 /// NM_001284281 /// NM_017936 /// NM_032560 /// XM_005267842 /// XM_006720194 /// XR_245702 /// XR_245703 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030289 // protein phosphatase 4 complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220369_at NM_017936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017936.1 /DEF=Homo sapiens hypothetical protein FLJ20707 (FLJ20707), mRNA. /FEA=mRNA /GEN=FLJ20707 /PROD=hypothetical protein FLJ20707 /DB_XREF=gi:8923637 /UG=Hs.109441 hypothetical protein FLJ20707 /FL=gb:NM_017936.1 NM_017936 SMEK homolog 1, suppressor of mek1 (Dictyostelium) SMEK1 55671 NM_001284280 /// NM_001284281 /// NM_017936 /// NM_032560 /// XM_005267842 /// XM_006720194 /// XR_245702 /// XR_245703 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030289 // protein phosphatase 4 complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 220370_s_at NM_025090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025090.1 /DEF=Homo sapiens KIAA1453 protein (KIAA1453), mRNA. /FEA=mRNA /GEN=KIAA1453 /PROD=hypothetical protein FLJ12851 /DB_XREF=gi:13435156 /UG=Hs.11387 KIAA1453 protein /FL=gb:NM_025090.1 NM_025090 ubiquitin specific peptidase 36 USP36 57602 NM_025090 /// XM_005257542 /// XM_005257543 /// XM_005257544 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220371_s_at NM_020246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020246.1 /DEF=Homo sapiens cation-chloride cotransporter-interacting protein (LOC56996), mRNA. /FEA=mRNA /GEN=LOC56996 /PROD=cation-chloride cotransporter-interactingprotein /DB_XREF=gi:9910385 /UG=Hs.119178 cation-chloride cotransporter-interacting protein /FL=gb:AB033284.1 gb:AF284422.1 gb:NM_020246.1 NM_020246 solute carrier family 12, member 9 SLC12A9 56996 NM_001267812 /// NM_001267814 /// NM_020246 /// XM_005250502 /// XM_005250503 /// XM_005250504 /// XM_006716054 /// XM_006716055 /// XM_006716056 /// XM_006716057 /// XM_006716058 /// XM_006716059 0006810 // transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015377 // cation:chloride symporter activity // traceable author statement 220372_at NM_017833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017833.1 /DEF=Homo sapiens hypothetical protein FLJ20461 (FLJ20461), mRNA. /FEA=mRNA /GEN=FLJ20461 /PROD=hypothetical protein FLJ20461 /DB_XREF=gi:8923432 /UG=Hs.121197 hypothetical protein FLJ20461 /FL=gb:NM_017833.1 NM_017833 DnaJ (Hsp40) homolog, subfamily C, member 28 DNAJC28 54943 NM_001040192 /// NM_017833 /// XM_006724027 /// XM_006725398 220373_at NM_017639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017639.1 /DEF=Homo sapiens hypothetical protein FLJ20047 (FLJ20047), mRNA. /FEA=mRNA /GEN=FLJ20047 /PROD=hypothetical protein FLJ20047 /DB_XREF=gi:8923054 /UG=Hs.12347 hypothetical protein FLJ20047 /FL=gb:NM_017639.1 NM_017639 dachsous cadherin-related 2 DCHS2 54798 NM_001142552 /// NM_001142553 /// NM_017639 /// NM_199348 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 220374_at NM_017658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017658.1 /DEF=Homo sapiens hypothetical protein FLJ20081 (FLJ20081), mRNA. /FEA=mRNA /GEN=FLJ20081 /PROD=hypothetical protein FLJ20081 /DB_XREF=gi:8923089 /UG=Hs.126219 hypothetical protein FLJ20081 /FL=gb:NM_017658.1 NM_017658 kelch-like family member 28 KLHL28 54813 NM_017658 /// XM_005267769 /// XM_005267770 /// XM_006720174 220375_s_at NM_024752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024752.1 /DEF=Homo sapiens hypothetical protein FLJ23312 (FLJ23312), mRNA. /FEA=mRNA /GEN=FLJ23312 /PROD=hypothetical protein FLJ23312 /DB_XREF=gi:13376081 /UG=Hs.126555 hypothetical protein FLJ23312 /FL=gb:NM_024752.1 NM_024752 chromosome 5 open reading frame 66 C5orf66 100996485 NM_001277348 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001558 // regulation of cell growth // inferred from genetic interaction /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // non-traceable author statement /// 0007549 // dosage compensation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from mutant phenotype /// 0045814 // negative regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0061187 // regulation of chromatin silencing at rDNA // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from mutant phenotype /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from genetic interaction /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype /// 1902750 // negative regulation of cell cycle G2/M phase transition // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0000786 // nucleosome // non-traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0001739 // sex chromatin // traceable author statement /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000182 // rDNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010385 // double-stranded methylated DNA binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220376_at NM_022901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022901.1 /DEF=Homo sapiens hypothetical protein FLJ21302 (FLJ21302), mRNA. /FEA=mRNA /GEN=FLJ21302 /PROD=hypothetical protein FLJ21302 /DB_XREF=gi:12597640 /UG=Hs.128071 hypothetical protein FLJ21302 /FL=gb:NM_022901.1 NM_022901 leucine rich repeat containing 19 LRRC19 64922 NM_022901 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220377_at NM_014151 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014151.1 /DEF=Homo sapiens HSPC053 protein (HSPC053), mRNA. /FEA=mRNA /GEN=HSPC053 /PROD=HSPC053 protein /DB_XREF=gi:7661757 /UG=Hs.128155 HSPC053 protein /FL=gb:AF161538.1 gb:NM_014151.1 NM_014151 KIAA0125 KIAA0125 9834 NM_014151 /// NM_014792 /// NR_026800 220378_at NM_018679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018679.1 /DEF=Homo sapiens t-complex 11 (a murine tcp homolog) (TCP11), mRNA. /FEA=mRNA /GEN=TCP11 /PROD=t-complex 11 (a murine tcp homolog) /DB_XREF=gi:8924255 /UG=Hs.128322 t-complex 11 (a murine tcp homolog) /FL=gb:AF269223.1 gb:NM_018679.1 NM_018679 t-complex 11, testis-specific TCP11 6954 NM_001093728 /// NM_001261817 /// NM_001261818 /// NM_001261819 /// NM_001261820 /// NM_001261821 /// NM_018679 /// XM_005249337 /// XM_005249338 /// XM_005249339 /// XM_006715172 /// XM_006715173 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220379_at NM_020369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020369.1 /DEF=Homo sapiens fascin (Strongylocentrotus purpuratus) homolog 3 (actin-bundling protein, testicular) (FSCN3), mRNA. /FEA=mRNA /GEN=FSCN3 /PROD=fascin (Strongylocentrotus purpuratus) homolog 3(actin-bundling protein, testicular) /DB_XREF=gi:9966790 /UG=Hs.128402 fascin (Strongylocentrotus purpuratus) homolog 3 (actin-bundling protein, testicular) /FL=gb:AF281049.1 gb:NM_020369.1 NM_020369 fascin actin-bundling protein 3, testicular FSCN3 29999 NM_020369 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 220380_at NM_021233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021233.1 /DEF=Homo sapiens deoxyribonuclease II beta (LOC58511), mRNA. /FEA=mRNA /GEN=LOC58511 /PROD=deoxyribonuclease II beta /DB_XREF=gi:10864044 /UG=Hs.129142 deoxyribonuclease II beta /FL=gb:NM_021233.1 gb:AF274571.1 NM_021233 deoxyribonuclease II beta DNASE2B 58511 NM_021233 /// NM_058248 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // not recorded /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004520 // endodeoxyribonuclease activity // inferred from electronic annotation /// 0004531 // deoxyribonuclease II activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation 220381_at NM_030672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030672.1 /DEF=Homo sapiens hypothetical protein FLJ10312 (FLJ10312), mRNA. /FEA=mRNA /GEN=FLJ10312 /PROD=hypothetical protein FLJ10312 /DB_XREF=gi:13491175 /UG=Hs.132560 hypothetical protein FLJ10312 /FL=gb:NM_030672.1 NM_030672 Rho GTPase activating protein 28 ARHGAP28 79822 NM_001010000 /// NM_030672 /// XM_005258144 /// XM_005258145 /// XM_005258146 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation 220382_s_at NM_030672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030672.1 /DEF=Homo sapiens hypothetical protein FLJ10312 (FLJ10312), mRNA. /FEA=mRNA /GEN=FLJ10312 /PROD=hypothetical protein FLJ10312 /DB_XREF=gi:13491175 /UG=Hs.132560 hypothetical protein FLJ10312 /FL=gb:NM_030672.1 NM_030672 Rho GTPase activating protein 28 ARHGAP28 79822 NM_001010000 /// NM_030672 /// XM_005258144 /// XM_005258145 /// XM_005258146 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation 220383_at NM_022436 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022436.1 /DEF=Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) (ABCG5), mRNA. /FEA=mRNA /GEN=ABCG5 /PROD=ATP-binding cassette, sub-family G (WHITE),member 5 (sterolin 1) /DB_XREF=gi:11967968 /UG=Hs.132992 ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) /FL=gb:AF320293.1 gb:NM_022436.1 gb:AF312715.1 NM_022436 ATP-binding cassette, sub-family G (WHITE), member 5 ABCG5 64240 NM_022436 /// XM_005264480 /// XM_005264481 /// XM_006712073 /// XM_006712074 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007588 // excretion // inferred from genetic interaction /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010949 // negative regulation of intestinal phytosterol absorption // inferred from mutant phenotype /// 0015918 // sterol transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // inferred by curator /// 0033344 // cholesterol efflux // inferred from genetic interaction /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045796 // negative regulation of intestinal cholesterol absorption // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from mutant phenotype /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from genetic interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 220384_at NM_016616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016616.1 /DEF=Homo sapiens NM23-H8 (LOC51314), mRNA. /FEA=mRNA /GEN=LOC51314 /PROD=NM23-H8 /DB_XREF=gi:7706153 /UG=Hs.134079 NM23-H8 /FL=gb:AF202051.2 gb:NM_016616.1 NM_016616 NME/NM23 family member 8 NME8 51314 NM_016616 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 220385_at NM_020433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020433.1 /DEF=Homo sapiens hypothetical protein LOC57158 (LOC57158), mRNA. /FEA=mRNA /GEN=LOC57158 /PROD=hypothetical protein LOC57158 /DB_XREF=gi:9967091 /UG=Hs.134594 hypothetical protein LOC57158 /FL=gb:NM_020433.1 NM_020433 junctophilin 2 JPH2 57158 NM_020433 /// NM_175913 /// XM_006723832 /// XM_006723833 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055024 // regulation of cardiac muscle tissue development // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060402 // calcium ion transport into cytosol // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030314 // junctional membrane complex // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0010314 // phosphatidylinositol-5-phosphate binding // inferred from direct assay /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0070273 // phosphatidylinositol-4-phosphate binding // inferred from direct assay /// 0070300 // phosphatidic acid binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay 220386_s_at NM_019063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019063.1 /DEF=Homo sapiens chromosome 2 open reading frame 2 (C2ORF2), mRNA. /FEA=mRNA /GEN=C2ORF2 /PROD=hypothetical protein /DB_XREF=gi:9506630 /UG=Hs.13472 chromosome 2 open reading frame 2 /FL=gb:NM_019063.1 NM_019063 echinoderm microtubule associated protein like 4 EML4 27436 NM_001145076 /// NM_019063 /// XM_005264267 /// XM_005264268 /// XM_006711991 /// XM_006711992 0007017 // microtubule-based process // non-traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220387_s_at NM_007071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007071.1 /DEF=Homo sapiens HERV-H LTR-associating 3 (HHLA3), mRNA. /FEA=mRNA /GEN=HHLA3 /PROD=HERV-H LTR-associating 3 /DB_XREF=gi:5901965 /UG=Hs.142245 HERV-H LTR-associating 3 /FL=gb:AF126164.1 gb:NM_007071.1 NM_007071 HERV-H LTR-associating 3 HHLA3 11147 NM_001031693 /// NM_001036645 /// NM_001036646 /// NM_007071 /// NR_027404 0005515 // protein binding // inferred from physical interaction 220388_at NM_024777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024777.1 /DEF=Homo sapiens hypothetical protein FLJ22613 (FLJ22613), mRNA. /FEA=mRNA /GEN=FLJ22613 /PROD=hypothetical protein FLJ22613 /DB_XREF=gi:13376130 /UG=Hs.144020 hypothetical protein FLJ22613 /FL=gb:NM_024777.1 NM_024777 fer-1-like family member 4, pseudogene (functional) FER1L4 80307 NR_001442 /// NR_024377 /// NR_119376 /// XR_425236 /// XR_430316 /// XR_433611 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220389_at NM_021827 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021827.1 /DEF=Homo sapiens hypothetical protein FLJ23514 (FLJ23514), mRNA. /FEA=mRNA /GEN=FLJ23514 /PROD=hypothetical protein FLJ23514 /DB_XREF=gi:11141904 /UG=Hs.144913 hypothetical protein FLJ23514 /FL=gb:NM_021827.1 NM_021827 coiled-coil domain containing 81 CCDC81 60494 NM_001156474 /// NM_021827 /// XM_005274161 /// XM_005274162 0003677 // DNA binding // inferred from electronic annotation 220390_at NM_024783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024783.1 /DEF=Homo sapiens hypothetical protein FLJ23598 (FLJ23598), mRNA. /FEA=mRNA /GEN=FLJ23598 /PROD=hypothetical protein FLJ23598 /DB_XREF=gi:13376143 /UG=Hs.147377 hypothetical protein FLJ23598 /FL=gb:NM_024783.1 NM_024783 ATP/GTP binding protein-like 2 AGBL2 79841 NM_024783 /// XM_005253138 /// XM_005253139 /// XM_005253140 /// XM_005253141 /// XM_006718326 /// XM_006718327 /// XM_006718328 /// XM_006718329 /// XR_242823 /// XR_242824 /// XR_428852 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220391_at NM_024784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024784.1 /DEF=Homo sapiens hypothetical protein FLJ23392 (FLJ23392), mRNA. /FEA=mRNA /GEN=FLJ23392 /PROD=hypothetical protein FLJ23392 /DB_XREF=gi:13376145 /UG=Hs.147554 hypothetical protein FLJ23392 /FL=gb:NM_024784.1 NM_024784 zinc finger and BTB domain containing 3 ZBTB3 79842 NM_024784 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220392_at NM_022659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022659.1 /DEF=Homo sapiens hypothetical protein FLJ11500 similar to EBF2 (FLJ11500), mRNA. /FEA=mRNA /GEN=FLJ11500 /PROD=hypothetical protein FLJ11500 similar to EBF2 /DB_XREF=gi:12056972 /UG=Hs.148533 hypothetical protein FLJ11500 similar to EBF2 /FL=gb:NM_022659.1 NM_022659 early B-cell factor 2 EBF2 64641 NM_022659 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220393_at NM_016571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016571.1 /DEF=Homo sapiens lengsin (LGS), mRNA. /FEA=mRNA /GEN=LGS /PROD=lengsin /DB_XREF=gi:7705581 /UG=Hs.149585 lengsin /FL=gb:AF242388.1 gb:NM_016571.1 NM_016571 lengsin, lens protein with glutamine synthetase domain LGSN 51557 NM_001143940 /// NM_016571 0006542 // glutamine biosynthetic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // inferred from electronic annotation 220394_at NM_019851 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019851.1 /DEF=Homo sapiens fibroblast growth factor 20 (FGF20), mRNA. /FEA=mRNA /GEN=FGF20 /PROD=fibroblast growth factor 20 /DB_XREF=gi:9789946 /UG=Hs.154302 fibroblast growth factor 20 /FL=gb:AB030648.1 gb:AB044277.1 gb:NM_019851.1 NM_019851 fibroblast growth factor 20 FGF20 26281 NM_019851 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060043 // regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 220395_at NM_018602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018602.1 /DEF=Homo sapiens hypothetical protein PRO1472 (PRO1472), mRNA. /FEA=mRNA /GEN=PRO1472 /PROD=hypothetical protein PRO1472 /DB_XREF=gi:8924043 /UG=Hs.154662 DnaJ (Hsp40) homolog, subfamily A, member 4 /FL=gb:AF116663.1 gb:NM_018602.1 NM_018602 DnaJ (Hsp40) homolog, subfamily A, member 4 DNAJA4 55466 NM_001130182 /// NM_001130183 /// NM_018602 /// XM_005254535 /// XM_006720601 0006457 // protein folding // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005524 // ATP binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 220396_at NM_018520 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018520.1 /DEF=Homo sapiens hypothetical protein PRO2268 (PRO2268), mRNA. /FEA=mRNA /GEN=PRO2268 /PROD=hypothetical protein PRO2268 /DB_XREF=gi:8924146 /UG=Hs.155860 hypothetical protein PRO2268 /FL=gb:AF119871.1 gb:NM_018520.1 NM_018520 solute carrier family 35, member E3 SLC35E3 55508 NM_018656 /// XM_005269006 /// XM_006719475 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220397_at NM_020128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020128.1 /DEF=Homo sapiens nuclear protein double minute 1 (MDM1), mRNA. /FEA=mRNA /GEN=MDM1 /PROD=nuclear protein double minute 1 /DB_XREF=gi:9910417 /UG=Hs.156163 nuclear protein double minute 1 /FL=gb:AF267851.1 gb:NM_020128.1 NM_020128 Mdm1 nuclear protein homolog (mouse) MDM1 56890 NM_001205028 /// NM_001205029 /// NM_017440 /// NM_020128 /// XM_005269026 /// XM_005269027 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 220398_at NM_024312 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024312.1 /DEF=Homo sapiens hypothetical protein MGC4170 (MGC4170), mRNA. /FEA=mRNA /GEN=MGC4170 /PROD=hypothetical protein MGC4170 /DB_XREF=gi:13236550 /UG=Hs.157081 hypothetical protein MGC4170 /FL=gb:BC002779.1 gb:NM_024312.1 NM_024312 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits GNPTAB 79158 NM_024312 /// XM_006719593 0007040 // lysosome organization // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003976 // UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220399_at NM_024796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024796.1 /DEF=Homo sapiens hypothetical protein FLJ22639 (FLJ22639), mRNA. /FEA=mRNA /GEN=FLJ22639 /PROD=hypothetical protein FLJ22639 /DB_XREF=gi:13376167 /UG=Hs.157184 hypothetical protein FLJ22639 /FL=gb:NM_024796.1 NM_024796 long intergenic non-protein coding RNA 115 LINC00115 79854 NM_024796 /// NR_024321 220400_at NM_017890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017890.1 /DEF=Homo sapiens hypothetical protein FLJ20583 (FLJ20583), mRNA. /FEA=mRNA /GEN=FLJ20583 /PROD=hypothetical protein FLJ20583 /DB_XREF=gi:8923544 /UG=Hs.158836 hypothetical protein FLJ20583 /FL=gb:NM_017890.1 NM_017890 vacuolar protein sorting 13 homolog B (yeast) VPS13B 157680 NM_015243 /// NM_017890 /// NM_152564 /// NM_181661 /// NM_184042 /// NR_047582 /// XM_005250800 /// XM_005250801 /// XM_006716510 /// XM_006716511 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 220401_at NM_024802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024802.1 /DEF=Homo sapiens hypothetical protein FLJ21369 (FLJ21369), mRNA. /FEA=mRNA /GEN=FLJ21369 /PROD=hypothetical protein FLJ21369 /DB_XREF=gi:13376178 /UG=Hs.159346 hypothetical protein FLJ21369 /FL=gb:NM_024802.1 NM_024802 uncharacterized protein FLJ21369 FLJ21369 79860 NM_024802 /// XR_108277 /// XR_109482 /// XR_172282 220402_at NM_022112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022112.1 /DEF=Homo sapiens p53-regulated apoptosis-inducing protein 1 (P53AIP1), mRNA. /FEA=mRNA /GEN=P53AIP1 /PROD=p53-regulated apoptosis-inducing protein 1 /DB_XREF=gi:11545826 /UG=Hs.160953 p53-regulated apoptosis-inducing protein 1 /FL=gb:AB045832.1 gb:NM_022112.1 NM_022112 tumor protein p53 regulated apoptosis inducing protein 1 TP53AIP1 63970 NM_001195194 /// NM_001195195 /// NM_001251964 /// NM_022112 0006915 // apoptotic process // traceable author statement 0005739 // mitochondrion // traceable author statement 220403_s_at NM_022112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022112.1 /DEF=Homo sapiens p53-regulated apoptosis-inducing protein 1 (P53AIP1), mRNA. /FEA=mRNA /GEN=P53AIP1 /PROD=p53-regulated apoptosis-inducing protein 1 /DB_XREF=gi:11545826 /UG=Hs.160953 p53-regulated apoptosis-inducing protein 1 /FL=gb:AB045832.1 gb:NM_022112.1 NM_022112 tumor protein p53 regulated apoptosis inducing protein 1 TP53AIP1 63970 NM_001195194 /// NM_001195195 /// NM_001251964 /// NM_022112 0006915 // apoptotic process // traceable author statement 0005739 // mitochondrion // traceable author statement 220404_at NM_014076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014076.1 /DEF=Homo sapiens PRO0611 protein (PRO0611), mRNA. /FEA=mRNA /GEN=PRO0611 /PROD=PRO0611 protein /DB_XREF=gi:7662571 /UG=Hs.163833 PRO0611 protein /FL=gb:AF111851.1 gb:NM_014076.1 NM_014076 G protein-coupled receptor 97 GPR97 222487 NM_170776 /// XM_005255842 /// XM_006721170 /// XR_243399 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220405_at NM_018967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018967.1 /DEF=Homo sapiens syntrophin, gamma 1 (SNTG1), mRNA. /FEA=mRNA /GEN=SNTG1 /PROD=syntrophin, gamma 1 /DB_XREF=gi:9507162 /UG=Hs.167481 syntrophin, gamma 1 /FL=gb:NM_018967.1 NM_018967 syntrophin, gamma 1 SNTG1 54212 NM_001287813 /// NM_001287814 /// NM_018967 /// XM_006716456 0007154 // cell communication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016013 // syntrophin complex // traceable author statement /// 0032587 // ruffle membrane // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction 220406_at NM_003238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_003238.1 /DEF=Homo sapiens transforming growth factor, beta 2 (TGFB2), mRNA. /FEA=mRNA /GEN=TGFB2 /PROD=transforming growth factor, beta 2 /DB_XREF=gi:4507462 /UG=Hs.169300 transforming growth factor, beta 2 /FL=gb:NM_003238.1 NM_003238 transforming growth factor, beta 2 TGFB2 7042 NM_001135599 /// NM_003238 /// XR_247036 /// XR_247037 0000902 // cell morphogenesis // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001654 // eye development // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001942 // hair follicle development // inferred from direct assay /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007507 // heart development // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008347 // glial cell migration // inferred from direct assay /// 0009611 // response to wounding // inferred from expression pattern /// 0009790 // embryo development // traceable author statement /// 0010002 // cardioblast differentiation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042416 // dopamine biosynthetic process // inferred from sequence or structural similarity /// 0042476 // odontogenesis // non-traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042637 // catagen // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045823 // positive regulation of heart contraction // inferred from direct assay /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048699 // generation of neurons // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050777 // negative regulation of immune response // traceable author statement /// 0050778 // positive regulation of immune response // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from direct assay /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0060038 // cardiac muscle cell proliferation // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070237 // positive regulation of activation-induced cell death of T cells // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement 220407_s_at NM_003238 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003238.1 /DEF=Homo sapiens transforming growth factor, beta 2 (TGFB2), mRNA. /FEA=mRNA /GEN=TGFB2 /PROD=transforming growth factor, beta 2 /DB_XREF=gi:4507462 /UG=Hs.169300 transforming growth factor, beta 2 /FL=gb:NM_003238.1 NM_003238 transforming growth factor, beta 2 TGFB2 7042 NM_001135599 /// NM_003238 /// XR_247036 /// XR_247037 0000902 // cell morphogenesis // inferred from direct assay /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001654 // eye development // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001942 // hair follicle development // inferred from direct assay /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0003007 // heart morphogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006924 // activation-induced cell death of T cells // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007507 // heart development // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008347 // glial cell migration // inferred from direct assay /// 0009611 // response to wounding // inferred from expression pattern /// 0009790 // embryo development // traceable author statement /// 0010002 // cardioblast differentiation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042416 // dopamine biosynthetic process // inferred from sequence or structural similarity /// 0042476 // odontogenesis // non-traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0042637 // catagen // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045726 // positive regulation of integrin biosynthetic process // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045823 // positive regulation of heart contraction // inferred from direct assay /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048666 // neuron development // inferred from sequence or structural similarity /// 0048699 // generation of neurons // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050777 // negative regulation of immune response // traceable author statement /// 0050778 // positive regulation of immune response // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051795 // positive regulation of catagen // inferred from direct assay /// 0051891 // positive regulation of cardioblast differentiation // inferred from direct assay /// 0060038 // cardiac muscle cell proliferation // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070237 // positive regulation of activation-induced cell death of T cells // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from mutant phenotype /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement 220408_x_at NM_017569 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017569.1 /DEF=Homo sapiens transcription factor (p38 interacting protein) (P38IP), mRNA. /FEA=mRNA /GEN=P38IP /PROD=transcription factor (p38 interacting protein) /DB_XREF=gi:8923734 /UG=Hs.171185 transcription factor (p38 interacting protein) /FL=gb:AF093250.1 gb:NM_017569.1 NM_017569 suppressor of Ty 20 homolog (S. cerevisiae) SUPT20H 55578 NM_001014286 /// NM_001278480 /// NM_001278481 /// NM_001278482 /// NM_017569 /// XM_005266447 /// XM_005266448 /// XM_005266449 /// XM_005266450 /// XM_005266451 /// XM_005266452 /// XM_005266453 /// XM_005266454 /// XM_005266455 /// XM_005266456 /// XM_005266457 /// XM_005266458 /// XM_005266460 /// XM_005266461 /// XM_005266462 /// XM_005266464 /// XM_005266465 /// XM_005266466 /// XM_005266467 /// XM_005266468 0006325 // chromatin organization // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000124 // SAGA complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220409_at NM_018627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018627.1 /DEF=Homo sapiens hypothetical protein PRO2405 (PRO2405), mRNA. /FEA=mRNA /GEN=PRO2405 /PROD=hypothetical protein PRO2405 /DB_XREF=gi:8924165 /UG=Hs.173958 hypothetical protein PRO2405 /FL=gb:AF116701.1 gb:NM_018627.1 NM_018627 calmodulin regulated spectrin-associated protein 1 CAMSAP1 157922 NM_015447 /// XM_005263396 /// XM_005263397 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from genetic interaction /// 0031175 // neuron projection development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay 220410_s_at NM_018627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018627.1 /DEF=Homo sapiens hypothetical protein PRO2405 (PRO2405), mRNA. /FEA=mRNA /GEN=PRO2405 /PROD=hypothetical protein PRO2405 /DB_XREF=gi:8924165 /UG=Hs.173958 hypothetical protein PRO2405 /FL=gb:AF116701.1 gb:NM_018627.1 NM_018627 calmodulin regulated spectrin-associated protein 1 CAMSAP1 157922 NM_015447 /// XM_005263396 /// XM_005263397 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from genetic interaction /// 0031175 // neuron projection development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0008017 // microtubule binding // inferred from direct assay /// 0030507 // spectrin binding // inferred from direct assay 220411_x_at NM_024825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024825.1 /DEF=Homo sapiens hypothetical protein FLJ23447 (FLJ23447), mRNA. /FEA=mRNA /GEN=FLJ23447 /PROD=hypothetical protein FLJ23447 /DB_XREF=gi:13376223 /UG=Hs.175024 hypothetical protein FLJ23447 /FL=gb:NM_024825.1 NM_024825 podocan-like 1 PODNL1 79883 NM_001146254 /// NM_001146255 /// NM_024825 /// XM_006722901 /// XM_006722902 /// XM_006722903 /// XM_006722904 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220412_x_at NM_005714 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005714.1 /DEF=Homo sapiens potassium channel, subfamily K, member 7 (KCNK7), mRNA. /FEA=mRNA /GEN=KCNK7 /PROD=potassium channel, subfamily K, member 7 /DB_XREF=gi:5031820 /UG=Hs.175218 potassium channel, subfamily K, member 7 /FL=gb:AF110524.1 gb:NM_005714.1 NM_005714 potassium channel, subfamily K, member 7 KCNK7 10089 NM_005714 /// NM_033347 /// NM_033348 /// NM_033455 /// NM_033456 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 220413_at NM_014579 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014579.1 /DEF=Homo sapiens zinc transporter (ZIP2), mRNA. /FEA=mRNA /GEN=ZIP2 /PROD=zinc transporter /DB_XREF=gi:7657698 /UG=Hs.175783 zinc transporter /FL=gb:AF186081.1 gb:D83039.1 gb:NM_014579.1 NM_014579 solute carrier family 39 (zinc transporter), member 2 SLC39A2 29986 NM_001256588 /// NM_014579 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from mutant phenotype /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 220414_at NM_017422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017422.2 /DEF=Homo sapiens calmodulin-like skin protein (CLSP), mRNA. /FEA=mRNA /GEN=CLSP /PROD=calmodulin-like skin protein /DB_XREF=gi:13699870 /UG=Hs.180142 calmodulin-like skin protein /FL=gb:NM_017422.2 gb:AF172852.1 NM_017422 calmodulin-like 5 CALML5 51806 NM_017422 0007165 // signal transduction // traceable author statement /// 0008544 // epidermis development // traceable author statement 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220415_at NM_015978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015978.1 /DEF=Homo sapiens putative protein-tyrosine kinase (LOC51086), mRNA. /FEA=mRNA /GEN=LOC51086 /PROD=putative protein-tyrosine kinase /DB_XREF=gi:7705747 /UG=Hs.180340 putative protein-tyrosine kinase /FL=gb:AF116826.1 gb:NM_015978.1 NM_015978 FPGT-TNNI3K readthrough /// TNNI3 interacting kinase FPGT-TNNI3K /// TNNI3K 51086 /// 100526835 NM_001112808 /// NM_001199327 /// NM_015978 0006004 // fucose metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031013 // troponin I binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047341 // fucose-1-phosphate guanylyltransferase activity // inferred from electronic annotation 220416_at NM_024837 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024837.1 /DEF=Homo sapiens hypothetical protein FLJ21472 (FLJ21472), mRNA. /FEA=mRNA /GEN=FLJ21472 /PROD=hypothetical protein FLJ21472 /DB_XREF=gi:13376248 /UG=Hs.182738 hypothetical protein FLJ21472 /FL=gb:NM_024837.1 NM_024837 ATPase, class I, type 8B, member 4 ATP8B4 79895 NM_024837 /// NR_073596 /// NR_073597 /// NR_073598 /// XM_006720693 /// XM_006720694 /// XM_006720695 /// XM_006720696 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220417_s_at NM_015963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015963.1 /DEF=Homo sapiens CGI-36 protein (LOC51078), mRNA. /FEA=mRNA /GEN=LOC51078 /PROD=CGI-36 protein /DB_XREF=gi:7705731 /UG=Hs.182986 CGI-36 protein /FL=gb:AF132970.1 gb:NM_015963.1 NM_015963 THAP domain containing 4 THAP4 51078 NM_001164356 /// NM_015963 /// XM_005247016 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220418_at NM_018961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018961.1 /DEF=Homo sapiens ubiquitin associated and SH3 domain containing, A (UBASH3A), mRNA. /FEA=mRNA /GEN=UBASH3A /PROD=ubiquitin associated and SH3 domain containing,A /DB_XREF=gi:9507220 /UG=Hs.183924 ubiquitin associated and SH3 domain containing, A /FL=gb:NM_018961.1 NM_018961 ubiquitin associated and SH3 domain containing A UBASH3A 53347 NM_001001895 /// NM_001243467 /// NM_018961 /// XM_006724013 /// XR_244316 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220419_s_at NM_013396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013396.1 /DEF=Homo sapiens ubiquitin specific protease 25 (USP25), mRNA. /FEA=mRNA /GEN=USP25 /PROD=ubiquitin specific protease 25 /DB_XREF=gi:7019564 /UG=Hs.186961 ubiquitin specific protease 25 /FL=gb:AF134213.1 gb:NM_013396.1 NM_013396 ubiquitin specific peptidase 25 USP25 29761 NM_001283041 /// NM_001283042 /// NM_013396 /// XM_005260949 /// XM_006723992 /// XR_430349 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from mutant phenotype /// 0071108 // protein K48-linked deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // traceable author statement /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032183 // SUMO binding // inferred from direct assay /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 220420_at NM_021819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021819.1 /DEF=Homo sapiens ERGL protein (ERGL), mRNA. /FEA=mRNA /GEN=ERGL /PROD=ERGL protein /DB_XREF=gi:11141890 /UG=Hs.187694 ERGL protein /FL=gb:AF303398.1 gb:NM_021819.1 NM_021819 lectin, mannose-binding, 1 like LMAN1L 79748 NM_021819 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005326 // neurotransmitter transporter activity // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 220421_at NM_024850 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024850.1 /DEF=Homo sapiens hypothetical protein FLJ21458 (FLJ21458), mRNA. /FEA=mRNA /GEN=FLJ21458 /PROD=hypothetical protein FLJ21458 /DB_XREF=gi:13376270 /UG=Hs.189109 hypothetical protein FLJ21458 /FL=gb:NM_024850.1 NM_024850 butyrophilin-like 8 BTNL8 79908 NM_001040462 /// NM_001159707 /// NM_001159708 /// NM_001159709 /// NM_001159710 /// NM_024850 /// XM_006714919 0002376 // immune system process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220422_at NM_017481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017481.1 /DEF=Homo sapiens ubiquilin 3 (UBQLN3), mRNA. /FEA=mRNA /GEN=UBQLN3 /PROD=ubiquilin 3 /DB_XREF=gi:8567417 /UG=Hs.189184 ubiquilin 3 /FL=gb:AF230481.1 gb:NM_017481.1 NM_017481 ubiquilin 3 UBQLN3 50613 NM_017481 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220423_at NM_012400 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012400.1 /DEF=Homo sapiens phospholipase A2, group IID (PLA2G2D), mRNA. /FEA=mRNA /GEN=PLA2G2D /PROD=phospholipase A2, group IID /DB_XREF=gi:6912595 /UG=Hs.189507 phospholipase A2, group IID /FL=gb:AF112982.1 gb:AF188625.1 gb:NM_012400.1 NM_012400 phospholipase A2, group IID PLA2G2D 26279 NM_001271814 /// NM_012400 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // traceable author statement 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220424_at NM_014625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014625.1 /DEF=Homo sapiens podocin (NPHS2), mRNA. /FEA=mRNA /GEN=NPHS2 /PROD=podocin /DB_XREF=gi:7657614 /UG=Hs.192657 NPHS2 gene (podocin) /FL=gb:NM_014625.1 NM_014625 nephrosis 2, idiopathic, steroid-resistant (podocin) NPHS2 7827 NM_014625 /// XM_005245483 /// XM_005245484 /// XM_006711529 0007588 // excretion // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0072249 // metanephric glomerular visceral epithelial cell development // inferred from expression pattern 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // inferred from direct assay /// 0036057 // slit diaphragm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220425_x_at NM_017578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017578.1 /DEF=Homo sapiens AKAP-binding sperm protein ropporin (DKFZp434B1222), mRNA. /FEA=mRNA /GEN=DKFZp434B1222 /PROD=AKAP-binding sperm protein ropporin /DB_XREF=gi:13487901 /UG=Hs.194093 AKAP-binding sperm protein ropporin /FL=gb:AF231410.1 gb:NM_017578.1 NM_017578 rhophilin associated tail protein 1B ROPN1B 152015 NM_001012337 /// XM_005247137 /// XM_005247138 /// XM_006713513 /// XM_006713514 0000910 // cytokinesis // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007283 // spermatogenesis // non-traceable author statement /// 0007340 // acrosome reaction // non-traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0030317 // sperm motility // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0031514 // motile cilium // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 220426_at NM_024059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024059.1 /DEF=Homo sapiens hypothetical protein MGC5356 (MGC5356), mRNA. /FEA=mRNA /GEN=MGC5356 /PROD=hypothetical protein MGC5356 /DB_XREF=gi:13129031 /UG=Hs.197755 hypothetical protein MGC5356 /FL=gb:BC000912.1 gb:NM_024059.1 NM_024059 chromosome 20 open reading frame 195 C20orf195 79025 NM_024059 /// XM_005260231 /// XM_005260232 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 220427_at NM_024868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024868.1 /DEF=Homo sapiens hypothetical protein FLJ14124 (FLJ14124), mRNA. /FEA=mRNA /GEN=FLJ14124 /PROD=hypothetical protein FLJ14124 /DB_XREF=gi:13376301 /UG=Hs.199542 hypothetical protein FLJ14124 /FL=gb:NM_024868.1 NM_024868 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF OBSCN 84033 NM_001098623 /// NM_001271223 /// NM_052843 /// XM_005273287 /// XM_005273288 /// XM_005273289 /// XM_005273290 /// XM_005273291 /// XM_005273292 /// XM_005273293 /// XM_005273294 /// XM_005273295 /// XM_005273296 /// XM_005273297 /// XM_005273298 /// XM_005273299 /// XM_005273300 /// XM_005273301 /// XM_005273302 /// XM_005273304 /// XM_005273305 /// XM_005273307 /// XM_005273309 /// XM_005273310 /// XM_006711819 /// XM_006711820 /// XM_006711821 /// XM_006711822 /// XM_006711823 /// XM_006711824 /// XM_006711825 /// XM_006711826 /// XM_006711827 /// XM_006711828 /// XM_006711829 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0045214 // sarcomere organization // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030016 // myofibril // non-traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220428_at NM_015717 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015717.1 /DEF=Homo sapiens Langerhans cell specific c-type lectin (LANGERIN), mRNA. /FEA=mRNA /GEN=LANGERIN /PROD=Langerhans cell specific c-type lectin /DB_XREF=gi:7657290 /UG=Hs.199731 Langerhans cell specific c-type lectin /FL=gb:NM_015717.1 NM_015717 CD207 molecule, langerin CD207 50489 NM_015717 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement 0005537 // mannose binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from direct assay 220429_at NM_004784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004784.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 3 (NDST3), mRNA. /FEA=mRNA /GEN=NDST3 /PROD=N-deacetylaseN-sulfotransferase (heparanglucosaminyl) 3 /DB_XREF=gi:4758765 /UG=Hs.20028 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 3 /FL=gb:AF074924.1 gb:NM_004784.1 gb:AF076605.1 NM_004784 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 NDST3 9348 NM_004784 /// XM_006714416 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030210 // heparin biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 220430_at NM_024869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024869.1 /DEF=Homo sapiens hypothetical protein FLJ14050 (FLJ14050), mRNA. /FEA=mRNA /GEN=FLJ14050 /PROD=hypothetical protein FLJ14050 /DB_XREF=gi:13376303 /UG=Hs.201737 hypothetical protein FLJ14050 /FL=gb:NM_024869.1 NM_024869 family with sequence similarity 110, member D FAM110D 79927 NM_024869 /// XM_005246002 220431_at NM_014058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014058.1 /DEF=Homo sapiens DESC1 protein (DESC1), mRNA. /FEA=mRNA /GEN=DESC1 /PROD=DESC1 protein /DB_XREF=gi:7661557 /UG=Hs.201877 DESC1 protein /FL=gb:AF064819.1 gb:NM_014058.1 NM_014058 transmembrane protease, serine 11E TMPRSS11E 28983 NM_014058 0006508 // proteolysis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 220432_s_at NM_016593 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016593.1 /DEF=Homo sapiens oxysterol 7alpha-hydroxylase (CYP39A1), mRNA. /FEA=mRNA /GEN=CYP39A1 /PROD=oxysterol 7alpha-hydroxylase /DB_XREF=gi:7706128 /UG=Hs.20766 oxysterol 7alpha-hydroxylase /FL=gb:AF237982.1 gb:NM_016593.1 NM_016593 cytochrome P450, family 39, subfamily A, polypeptide 1 CYP39A1 51302 NM_001278738 /// NM_001278739 /// NM_016593 /// XM_005249171 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006699 // bile acid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007586 // digestion // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0030573 // bile acid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008387 // steroid 7-alpha-hydroxylase activity // inferred from electronic annotation /// 0008396 // oxysterol 7-alpha-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0033782 // 24-hydroxycholesterol 7alpha-hydroxylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220433_at NM_024082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024082.1 /DEF=Homo sapiens transmembrane gamma-carboxyglutamic acid protein 3 (TMG3), mRNA. /FEA=mRNA /GEN=TMG3 /PROD=transmembrane gamma-carboxyglutamic acid protein3 /DB_XREF=gi:13129075 /UG=Hs.209253 transmembrane gamma-carboxyglutamic acid protein 3 /FL=gb:AF326350.1 gb:NM_024082.1 NM_024082 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) PRRG3 79057 NM_024082 /// NR_033262 /// XM_005274747 /// XM_006724845 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 220434_at NM_024876 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024876.1 /DEF=Homo sapiens hypothetical protein FLJ12229 (FLJ12229), mRNA. /FEA=mRNA /GEN=FLJ12229 /PROD=hypothetical protein FLJ12229 /DB_XREF=gi:13376315 /UG=Hs.209639 hypothetical protein FLJ12229 /FL=gb:NM_024876.1 NM_024876 aarF domain containing kinase 4 ADCK4 79934 NM_001142555 /// NM_024876 /// XM_005259270 /// XM_005259271 /// XM_005259272 /// XM_005259273 /// XM_005259274 /// XM_006723392 /// XM_006723393 /// XM_006723394 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220435_at NM_018713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018713.1 /DEF=Homo sapiens hypothetical protein DKFZp547M236 (DKFZp547M236), mRNA. /FEA=mRNA /GEN=DKFZp547M236 /PROD=hypothetical protein DKFZp547M236 /DB_XREF=gi:8922154 /UG=Hs.20981 hypothetical protein DKFZp547M236 /FL=gb:NM_018713.1 NM_018713 solute carrier family 30, member 10 SLC30A10 55532 NM_001004433 /// NM_018713 /// NR_046437 /// XM_006711437 /// XM_006711438 /// XM_006711439 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 220436_at NM_024879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024879.1 /DEF=Homo sapiens hypothetical protein FLJ14195 (FLJ14195), mRNA. /FEA=mRNA /GEN=FLJ14195 /PROD=hypothetical protein FLJ14195 /DB_XREF=gi:13376319 /UG=Hs.212839 hypothetical protein FLJ14195; KIAA1714 protein /FL=gb:NM_024879.1 NM_024879 contactin associated protein-like 3 pseudogene 2 CNTNAP3P2 643827 NM_001012280 /// NR_111893 /// XR_432398 /// XR_432399 /// XR_432400 /// XR_432401 /// XR_432402 /// XR_432403 /// XR_432404 /// XR_432405 /// XR_432406 /// XR_432407 0007155 // cell adhesion // inferred from electronic annotation /// 0008037 // cell recognition // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 220437_at NM_018687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018687.1 /DEF=Homo sapiens hepatocellular carcinoma-associated gene TD26 (LOC55908), mRNA. /FEA=mRNA /GEN=LOC55908 /PROD=hepatocellular carcinoma-associated gene TD26 /DB_XREF=gi:8923901 /UG=Hs.224121 hepatocellular carcinoma-associated gene TD26 /FL=gb:NM_018687.1 NM_018687 chromosome 19 open reading frame 80 C19orf80 55908 NM_018687 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0010954 // positive regulation of protein processing // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from sequence or structural similarity /// 0044342 // type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050746 // regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0070328 // triglyceride homeostasis // inferred from genetic interaction 0005576 // extracellular region // inferred from direct assay 0005179 // hormone activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 220438_at NM_017659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017659.1 /DEF=Homo sapiens hypothetical protein FLJ20084 (FLJ20084), mRNA. /FEA=mRNA /GEN=FLJ20084 /PROD=hypothetical protein FLJ20084 /DB_XREF=gi:8923091 /UG=Hs.231436 hypothetical protein FLJ20084 /FL=gb:NM_017659.1 NM_017659 glutaminyl-peptide cyclotransferase-like QPCTL 54814 NM_001163377 /// NM_017659 0006508 // proteolysis // inferred from electronic annotation /// 0017186 // peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016603 // glutaminyl-peptide cyclotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220439_at NM_024892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024892.1 /DEF=Homo sapiens hypothetical protein FLJ11700 (FLJ11700), mRNA. /FEA=mRNA /GEN=FLJ11700 /PROD=hypothetical protein FLJ11700 /DB_XREF=gi:13376344 /UG=Hs.233395 hypothetical protein FLJ11700 /FL=gb:NM_024892.1 NM_024892 Ras and Rab interactor 3 RIN3 79890 NM_024832 0006897 // endocytosis // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0017137 // Rab GTPase binding // inferred from direct assay 220440_at NM_013268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013268.1 /DEF=Homo sapiens placental protein 13 (PP13), mRNA. /FEA=mRNA /GEN=PP13 /PROD=placental protein 13 /DB_XREF=gi:7019496 /UG=Hs.23671 placental protein 13 /FL=gb:AF117383.1 gb:NM_013268.1 NM_013268 lectin, galactoside-binding, soluble, 13 LGALS13 29124 NM_013268 0006644 // phospholipid metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation 0004622 // lysophospholipase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 220441_at NM_024902 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024902.1 /DEF=Homo sapiens hypothetical protein FLJ13236 (FLJ13236), mRNA. /FEA=mRNA /GEN=FLJ13236 /PROD=hypothetical protein FLJ13236 /DB_XREF=gi:13376360 /UG=Hs.239515 hypothetical protein FLJ13236 /FL=gb:NM_024902.1 NM_024902 DnaJ (Hsp40) homolog, subfamily C, member 22 DNAJC22 79962 NM_024902 /// XM_005269153 /// XM_005269154 /// XM_005269155 /// XM_005269156 /// XM_005269157 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220442_at NM_003774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003774.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4), mRNA. /FEA=mRNA /GEN=GALNT4 /PROD=polypeptide N-acetylgalactosaminyltransferase 4 /DB_XREF=gi:13124892 /UG=Hs.248190 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) /FL=gb:NM_003774.2 NM_003774 polypeptide N-acetylgalactosaminyltransferase 4 /// POC1B-GALNT4 readthrough GALNT4 /// POC1B-GALNT4 8693 /// 100528030 NM_001199781 /// NM_001199782 /// NM_003774 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016266 // O-glycan processing // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0000922 // spindle pole // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220443_s_at NM_012476 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012476.1 /DEF=Homo sapiens ventral anterior homeobox 2 (VAX2), mRNA. /FEA=mRNA /GEN=VAX2 /PROD=ventral anterior homeobox 2 /DB_XREF=gi:7110734 /UG=Hs.249170 ventral anterior homeobox 2 /FL=gb:NM_012476.1 NM_012476 ventral anterior homeobox 2 VAX2 25806 NM_012476 /// XM_006711982 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220444_at NM_024341 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024341.1 /DEF=Homo sapiens hypothetical protein MGC4054 (MGC4054), mRNA. /FEA=mRNA /GEN=MGC4054 /PROD=hypothetical protein MGC4054 /DB_XREF=gi:13236592 /UG=Hs.250821 hypothetical protein MGC4054 /FL=gb:BC003020.1 gb:NM_024341.1 NM_024341 zinc finger protein 557 ZNF557 79230 NM_001044387 /// NM_001044388 /// NM_024341 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220445_s_at NM_004909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004909.1 /DEF=Homo sapiens taxol resistance associated gene 3 (TRAG3), mRNA. /FEA=mRNA /GEN=TRAG3 /PROD=taxol resistance associated gene 3 /DB_XREF=gi:4759255 /UG=Hs.251377 taxol resistance associated gene 3 /FL=gb:AF080246.1 gb:NM_004909.1 NM_004909 CSAG family, member 2 /// CSAG family, member 3 CSAG2 /// CSAG3 389903 /// 102723547 NM_001129826 /// NM_001129828 /// NM_203311 /// XM_006710263 /// XM_006724857 /// XM_006726859 0042493 // response to drug // traceable author statement 220446_s_at NM_005769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005769.1 /DEF=Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (CHST4), mRNA. /FEA=mRNA /GEN=CHST4 /PROD=carbohydrate (N-acetylglucosamine 6-O)sulfotransferase 4 /DB_XREF=gi:5031734 /UG=Hs.251383 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 /FL=gb:AF131235.1 gb:NM_005769.1 NM_005769 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 CHST4 10164 NM_001166395 /// NM_005769 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006477 // protein sulfation // inferred from electronic annotation /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // non-traceable author statement 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 220447_at NM_007232 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007232.1 /DEF=Homo sapiens histamine receptor H3 (HRH3), mRNA. /FEA=mRNA /GEN=HRH3 /PROD=histamine receptor H3 /DB_XREF=gi:6005781 /UG=Hs.251399 histamine receptor H3 /FL=gb:AB019000.1 gb:AF140538.1 gb:NM_007232.1 NM_007232 histamine receptor H3 HRH3 11255 NM_007232 /// XM_005260266 /// XM_005260267 /// XM_006723696 0001505 // regulation of neurotransmitter levels // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014053 // negative regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0014063 // negative regulation of serotonin secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation 220448_at NM_022055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022055.1 /DEF=Homo sapiens reserved (KCNK12), mRNA. /FEA=mRNA /GEN=KCNK12 /PROD=tandem pore domain potassium channel THIK-2 /DB_XREF=gi:11545760 /UG=Hs.252617 potassium channel, subfamily K, member 12 (THIK-2) /FL=gb:AF287302.1 gb:NM_022055.1 NM_022055 potassium channel, subfamily K, member 12 KCNK12 56660 NM_022055 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 220449_at NM_024049 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024049.1 /DEF=Homo sapiens hypothetical protein MGC5566 (MGC5566), mRNA. /FEA=mRNA /GEN=MGC5566 /PROD=hypothetical protein MGC5566 /DB_XREF=gi:13129013 /UG=Hs.255479 hypothetical protein MGC5566 /FL=gb:BC000849.1 gb:NM_024049.1 NM_024049 long intergenic non-protein coding RNA 1260 LINC01260 79015 NM_024049 /// NR_034104 220450_at NM_024914 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024914.1 /DEF=Homo sapiens hypothetical protein FLJ13262 (FLJ13262), mRNA. /FEA=mRNA /GEN=FLJ13262 /PROD=hypothetical protein FLJ13262 /DB_XREF=gi:13376379 /UG=Hs.255858 hypothetical protein FLJ13262 /FL=gb:NM_024914.1 NM_024914 220451_s_at NM_022161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022161.1 /DEF=Homo sapiens livin inhibitor-of-apotosis (LIVIN), mRNA. /FEA=mRNA /GEN=LIVIN /PROD=livin inhibitor-of-apotosis /DB_XREF=gi:11545909 /UG=Hs.256126 baculoviral IAP repeat-containing 7 (livin) /FL=gb:AF311388.1 gb:NM_022161.1 NM_022161 baculoviral IAP repeat containing 7 BIRC7 79444 NM_022161 /// NM_139317 0006309 // apoptotic DNA fragmentation // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // non-traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0070247 // regulation of natural killer cell apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004869 // cysteine-type endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220452_x_at NM_021031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021031.1 /DEF=Homo sapiens cytochrome c-like antigen (CYCL), mRNA. /FEA=mRNA /GEN=CYCL /PROD=cytochrome c-like antigen /DB_XREF=gi:10518341 /UG=Hs.262219 cytochrome c-like antigen /FL=gb:NM_021031.1 NM_021031 220453_at NM_017765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017765.1 /DEF=Homo sapiens hypothetical protein FLJ20320 (FLJ20320), mRNA. /FEA=mRNA /GEN=FLJ20320 /PROD=hypothetical protein FLJ20320 /DB_XREF=gi:8923300 /UG=Hs.263081 hypothetical protein FLJ20320 /FL=gb:NM_017765.1 NM_017765 PQ loop repeat containing 2 PQLC2 54896 NM_001040125 /// NM_001040126 /// NM_001287531 /// NM_017765 /// NR_109848 /// XM_005245915 /// XM_005245916 /// XM_006710710 /// XM_006710711 /// XR_241193 /// XR_241194 0003333 // amino acid transmembrane transport // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015809 // arginine transport // inferred from direct assay /// 0015819 // lysine transport // inferred from direct assay /// 0080144 // amino acid homeostasis // inferred from direct assay 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031301 // integral component of organelle membrane // inferred from direct assay 0015181 // arginine transmembrane transporter activity // inferred from direct assay /// 0015189 // L-lysine transmembrane transporter activity // inferred from direct assay /// 0015326 // cationic amino acid transmembrane transporter activity // inferred from sequence or structural similarity 220454_s_at NM_020796 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020796.1 /DEF=Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (SEMA6A), mRNA. /FEA=mRNA /GEN=SEMA6A /PROD=sema domain, transmembrane domain (TM), andcytoplasmic domain, (semaphorin) 6A /DB_XREF=gi:11991659 /UG=Hs.263395 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A /FL=gb:AF279656.1 gb:NM_020796.1 NM_020796 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A SEMA6A 57556 NM_020796 /// XM_005272041 /// XM_005272042 /// XM_006714663 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007010 // cytoskeleton organization // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 2001224 // positive regulation of neuron migration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // non-traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 220455_at NM_013356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013356.1 /DEF=Homo sapiens monocarboxylate transporter 3 (SLC16A8), mRNA. /FEA=mRNA /GEN=SLC16A8 /PROD=monocarboxylate transporter 3 /DB_XREF=gi:7019528 /UG=Hs.270285 solute carrier 16 (monocarboxylic acid transporters), member 8 /FL=gb:AF132610.1 gb:NM_013356.1 NM_013356 solute carrier family 16 (monocarboxylate transporter), member 8 SLC16A8 23539 NM_013356 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015727 // lactate transport // traceable author statement /// 0035873 // lactate transmembrane transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0015129 // lactate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation 220456_at NM_018327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018327.1 /DEF=Homo sapiens hypothetical protein FLJ11112 (FLJ11112), mRNA. /FEA=mRNA /GEN=FLJ11112 /PROD=hypothetical protein FLJ11112 /DB_XREF=gi:8922874 /UG=Hs.272242 hypothetical protein FLJ11112 /FL=gb:NM_018327.1 NM_018327 serine palmitoyltransferase, long chain base subunit 3 SPTLC3 55304 NM_018327 /// XR_244218 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046520 // sphingoid biosynthetic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 220457_at NM_018028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018028.1 /DEF=Homo sapiens hypothetical protein FLJ10211 (FLJ10211), mRNA. /FEA=mRNA /GEN=FLJ10211 /PROD=hypothetical protein FLJ10211 /DB_XREF=gi:8922288 /UG=Hs.274206 hypothetical protein FLJ10211 /FL=gb:NM_018028.1 NM_018028 sterile alpha motif domain containing 4B SAMD4B 55095 NM_018028 /// XM_005259028 /// XM_005259029 /// XM_005259030 /// XM_006723256 /// XM_006723257 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 220458_at NM_018038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018038.1 /DEF=Homo sapiens hypothetical protein FLJ10246 (FLJ10246), mRNA. /FEA=mRNA /GEN=FLJ10246 /PROD=hypothetical protein FLJ10246 /DB_XREF=gi:8922308 /UG=Hs.274274 hypothetical protein FLJ10246 /FL=gb:NM_018038.1 NM_018038 220459_at NM_018118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018118.1 /DEF=Homo sapiens hypothetical protein FLJ10508 (FLJ10508), mRNA. /FEA=mRNA /GEN=FLJ10508 /PROD=hypothetical protein FLJ10508 /DB_XREF=gi:8922473 /UG=Hs.274284 hypothetical protein FLJ10508 /FL=gb:NM_018118.1 NM_018118 MCM3AP antisense RNA 1 MCM3AP-AS1 114044 NR_002776 /// NR_110565 /// NR_110566 /// NR_110567 /// XR_244337 /// XR_249008 220460_at NM_017435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017435.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 14 (SLC21A14), mRNA. /FEA=mRNA /GEN=SLC21A14 /PROD=solute carrier family 21 (organic aniontransporter), member 14 /DB_XREF=gi:8394290 /UG=Hs.279005 solute carrier family 21 (organic anion transporter), member 14 /FL=gb:AF205076.1 gb:AF260704.1 gb:NM_017435.1 NM_017435 solute carrier organic anion transporter family, member 1C1 SLCO1C1 53919 NM_001145944 /// NM_001145945 /// NM_001145946 /// NM_017435 /// XM_005253394 /// XM_005253395 /// XM_005253396 /// XM_005253397 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 220461_at NM_024938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024938.1 /DEF=Homo sapiens hypothetical protein FLJ11383 (FLJ11383), mRNA. /FEA=mRNA /GEN=FLJ11383 /PROD=hypothetical protein FLJ11383 /DB_XREF=gi:13376414 /UG=Hs.279800 hypothetical protein FLJ11383 /FL=gb:NM_024938.1 NM_024938 pecanex-like 2 (Drosophila) PCNXL2 80003 NM_014801 /// NM_024938 /// XM_005273272 /// XM_006711816 /// XR_247042 /// XR_426918 /// XR_426919 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220462_at NM_024969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024969.1 /DEF=Homo sapiens hypothetical protein FLJ11703 (FLJ11703), mRNA. /FEA=mRNA /GEN=FLJ11703 /PROD=hypothetical protein FLJ11703 /DB_XREF=gi:13376463 /UG=Hs.287442 hypothetical protein FLJ11703 /FL=gb:NM_024969.1 NM_024969 cysteine-serine-rich nuclear protein 3 CSRNP3 80034 NM_001172173 /// NM_024969 /// XM_005246865 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220463_at NM_024971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024971.1 /DEF=Homo sapiens hypothetical protein FLJ11726 (FLJ11726), mRNA. /FEA=mRNA /GEN=FLJ11726 /PROD=hypothetical protein FLJ11726 /DB_XREF=gi:13376467 /UG=Hs.287445 hypothetical protein FLJ11726 /FL=gb:NM_024971.1 NM_024971 transient receptor potential cation channel, subfamily M, member 3 TRPM3 80036 NM_001007470 /// NM_001007471 /// NM_020952 /// NM_024971 /// NM_206944 /// NM_206945 /// NM_206946 /// NM_206947 /// NM_206948 /// XM_005252218 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation 220464_at NM_024979 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024979.1 /DEF=Homo sapiens hypothetical protein FLJ12122 (FLJ12122), mRNA. /FEA=mRNA /GEN=FLJ12122 /PROD=hypothetical protein FLJ12122 /DB_XREF=gi:13376481 /UG=Hs.287488 hypothetical protein FLJ12122 /FL=gb:NM_024979.1 NM_024979 MCF.2 cell line derived transforming sequence-like MCF2L 23263 NM_001112732 /// NM_024979 /// XM_005268307 /// XM_005268308 /// XM_005268309 /// XM_005268310 /// XM_005268312 /// XM_005268313 /// XM_005268314 /// XM_005268315 /// XM_005268316 /// XM_006719966 /// XM_006719967 /// XM_006719968 /// XR_429282 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from electronic annotation 220465_at NM_024988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024988.1 /DEF=Homo sapiens hypothetical protein FLJ12355 (FLJ12355), mRNA. /FEA=mRNA /GEN=FLJ12355 /PROD=hypothetical protein FLJ12355 /DB_XREF=gi:13376491 /UG=Hs.287521 hypothetical protein FLJ12355 /FL=gb:NM_024988.1 NM_024988 CEBPA antisense RNA 1 (head to head) CEBPA-AS1 80054 NM_024988 /// NR_026887 220466_at NM_025004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025004.1 /DEF=Homo sapiens hypothetical protein FLJ13215 (FLJ13215), mRNA. /FEA=mRNA /GEN=FLJ13215 /PROD=hypothetical protein FLJ13215 /DB_XREF=gi:13376518 /UG=Hs.287555 hypothetical protein FLJ13215 /FL=gb:NM_025004.1 NM_025004 coiled-coil domain containing 15 CCDC15 80071 NM_025004 /// XM_006718916 /// XM_006718917 /// XM_006718918 /// XM_006718919 /// XM_006718920 0005813 // centrosome // inferred from direct assay 220467_at NM_025032 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025032.1 /DEF=Homo sapiens hypothetical protein FLJ21272 (FLJ21272), mRNA. /FEA=mRNA /GEN=FLJ21272 /PROD=hypothetical protein FLJ21272 /DB_XREF=gi:13376557 /UG=Hs.287653 hypothetical protein FLJ21272 /FL=gb:NM_025032.1 NM_025032 220468_at NM_025047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025047.1 /DEF=Homo sapiens hypothetical protein FLJ22595 (FLJ22595), mRNA. /FEA=mRNA /GEN=FLJ22595 /PROD=hypothetical protein FLJ22595 /DB_XREF=gi:13376573 /UG=Hs.287702 hypothetical protein FLJ22595 /FL=gb:NM_025047.1 NM_025047 ADP-ribosylation factor-like 14 ARL14 80117 NM_025047 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 220469_at NM_025088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025088.1 /DEF=Homo sapiens hypothetical protein FLJ13241 (FLJ13241), mRNA. /FEA=mRNA /GEN=FLJ13241 /PROD=hypothetical protein FLJ13241 /DB_XREF=gi:13376645 /UG=Hs.288492 hypothetical protein FLJ13241 /FL=gb:NM_025088.1 NM_025088 coatomer protein complex, subunit epsilon COPE 11316 NM_007263 /// NM_199442 /// NM_199444 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 220470_at NM_016526 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016526.1 /DEF=Homo sapiens GS15 (LOC51272), mRNA. /FEA=mRNA /GEN=LOC51272 /PROD=GS15 /DB_XREF=gi:7706072 /UG=Hs.288631 GS15 /FL=gb:AF234160.1 gb:NM_016526.1 NM_016526 Bet1 golgi vesicular membrane trafficking protein-like BET1L 51272 NM_001098787 /// NM_016465 /// NM_016526 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement 0005484 // SNAP receptor activity // inferred from direct assay 220471_s_at NM_025107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025107.1 /DEF=Homo sapiens hypothetical protein FLJ21269 (FLJ21269), mRNA. /FEA=mRNA /GEN=FLJ21269 /PROD=hypothetical protein FLJ21269 /DB_XREF=gi:13376676 /UG=Hs.288669 hypothetical protein FLJ21269 /FL=gb:NM_025107.1 NM_025107 myc target 1 MYCT1 80177 NM_025107 0005634 // nucleus // inferred from electronic annotation 220472_at NM_014150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014150.1 /DEF=Homo sapiens HSPC052 protein (HSPC052), mRNA. /FEA=mRNA /GEN=HSPC052 /PROD=HSPC052 protein /DB_XREF=gi:7661755 /UG=Hs.296435 HSPC052 protein /FL=gb:AF161537.1 gb:NM_014150.1 NM_014150 zinc finger, CCHC domain containing 4 ZCCHC4 29063 NM_024936 /// XM_005248155 /// XM_005248156 /// XM_005248157 0032259 // methylation // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220473_s_at NM_014150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014150.1 /DEF=Homo sapiens HSPC052 protein (HSPC052), mRNA. /FEA=mRNA /GEN=HSPC052 /PROD=HSPC052 protein /DB_XREF=gi:7661755 /UG=Hs.296435 HSPC052 protein /FL=gb:AF161537.1 gb:NM_014150.1 NM_014150 zinc finger, CCHC domain containing 4 ZCCHC4 29063 NM_024936 /// XM_005248155 /// XM_005248156 /// XM_005248157 0032259 // methylation // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220474_at NM_030631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030631.1 /DEF=Homo sapiens oxodicarboxylate carrier (ODC1), mRNA. /FEA=mRNA /GEN=ODC1 /PROD=oxodicarboxylate carrier /DB_XREF=gi:13449278 /UG=Hs.297782 oxodicarboxylate carrier /FL=gb:NM_030631.1 NM_030631 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 SLC25A21 89874 NM_001171170 /// NM_030631 0006554 // lysine catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220475_at NM_022127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022127.1 /DEF=Homo sapiens concentrative Na+-nucleoside cotransporter (CNT3), mRNA. /FEA=mRNA /GEN=CNT3 /PROD=concentrative Na+-nucleoside cotransporter /DB_XREF=gi:11545852 /UG=Hs.306216 concentrative Na+-nucleoside cotransporter /FL=gb:AF305210.1 gb:NM_022127.1 NM_022127 solute carrier family 28 (concentrative nucleoside transporter), member 3 SLC28A3 64078 NM_001199633 /// NM_022127 /// NR_037638 0006810 // transport // inferred from electronic annotation /// 0006863 // purine nucleobase transport // inferred from electronic annotation /// 0015855 // pyrimidine nucleobase transport // inferred from electronic annotation /// 0015860 // purine nucleoside transmembrane transport // inferred from electronic annotation /// 0015864 // pyrimidine nucleoside transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072531 // pyrimidine-containing compound transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001882 // nucleoside binding // inferred from electronic annotation /// 0005415 // nucleoside:sodium symporter activity // inferred from electronic annotation /// 0015389 // pyrimidine- and adenine-specific:sodium symporter activity // inferred from electronic annotation /// 0015390 // purine-specific nucleoside:sodium symporter activity // inferred from electronic annotation 220476_s_at NM_019099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019099.1 /DEF=Homo sapiens hypothetical protein (LOC55924), mRNA. /FEA=mRNA /GEN=LOC55924 /PROD=hypothetical protein /DB_XREF=gi:9506860 /UG=Hs.30751 hypothetical protein /FL=gb:NM_019099.1 NM_019099 family with sequence similarity 212, member B /// uncharacterized LOC101928718 FAM212B /// LOC101928718 55924 /// 101928718 NM_019099 /// NM_198926 /// XR_246395 /// XR_246396 /// XR_248854 /// XR_248855 /// XR_250809 /// XR_250810 220477_s_at NM_014145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014145.1 /DEF=Homo sapiens HSPC274 protein (HSPC274), mRNA. /FEA=mRNA /GEN=HSPC274 /PROD=HSPC274 protein /DB_XREF=gi:7661833 /UG=Hs.323476 HSPC274 protein /FL=gb:AF161392.1 gb:NM_014145.1 NM_014145 transmembrane protein 230 TMEM230 29058 NM_001009923 /// NM_001009924 /// NM_001009925 /// NM_014145 /// XM_005260713 /// XM_006723561 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220478_at NM_030642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030642.1 /DEF=Homo sapiens apolipoprotein L, 5 (APOL5), mRNA. /FEA=mRNA /GEN=APOL5 /PROD=apolipoprotein L, 5 /DB_XREF=gi:13470093 /UG=Hs.326561 apolipoprotein L, 5 /FL=gb:AY014878.1 gb:NM_030642.1 NM_030642 apolipoprotein L, 5 APOL5 80831 NM_030642 /// XM_006724321 /// XM_006725403 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008035 // high-density lipoprotein particle binding // non-traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 220479_at NM_014116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014116.1 /DEF=Homo sapiens PRO0132 protein (PRO0132), mRNA. /FEA=mRNA /GEN=PRO0132 /PROD=PRO0132 protein /DB_XREF=gi:7662525 /UG=Hs.35416 PRO0132 protein /FL=gb:AF090897.1 gb:NM_014116.1 NM_014116 CPS1 intronic transcript 1 (non-protein coding) CPS1-IT1 29034 NR_002763 220480_at NM_021973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021973.1 /DEF=Homo sapiens heart and neural crest derivatives expressed 2 (HAND2), mRNA. /FEA=mRNA /GEN=HAND2 /PROD=basic helix-loop-helix transcription factorHAND2 /DB_XREF=gi:12545383 /UG=Hs.36029 heart and neural crest derivatives expressed 2 /FL=gb:NM_021973.1 NM_021973 heart and neural crest derivatives expressed 2 HAND2 9464 NM_021973 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0003219 // cardiac right ventricle formation // inferred from electronic annotation /// 0003253 // cardiac neural crest cell migration involved in outflow tract morphogenesis // inferred from electronic annotation /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003357 // noradrenergic neuron differentiation // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // non-traceable author statement /// 0007512 // adult heart development // inferred from expression pattern /// 0010463 // mesenchymal cell proliferation // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from sequence or structural similarity /// 0014032 // neural crest cell development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043586 // tongue development // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048485 // sympathetic nervous system development // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060485 // mesenchyme development // inferred from electronic annotation /// 0060536 // cartilage morphogenesis // inferred from electronic annotation /// 0060982 // coronary artery morphogenesis // inferred from electronic annotation /// 0061032 // visceral serous pericardium development // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061325 // cell proliferation involved in outflow tract morphogenesis // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000763 // positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process // inferred from sequence or structural similarity /// 2000764 // positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0033613 // activating transcription factor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 220481_at NM_006794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006794.1 /DEF=Homo sapiens G protein-coupled receptor 75 (GPR75), mRNA. /FEA=mRNA /GEN=GPR75 /PROD=G protein-coupled receptor 75 /DB_XREF=gi:5803024 /UG=Hs.40763 G protein-coupled receptor 75 /FL=gb:AF072693.1 gb:NM_006794.1 NM_006794 G protein-coupled receptor 75 GPR75 10936 NM_006794 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220482_s_at NM_012139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012139.1 /DEF=Homo sapiens deafness locus associated putative guanine nucleotide exchange factor (DELGEF), mRNA. /FEA=mRNA /GEN=DELGEF /PROD=deafness locus associated putative guaninenucleotide exchange factor /DB_XREF=gi:6912329 /UG=Hs.46735 deafness locus associated putative guanine nucleotide exchange factor /FL=gb:NM_012139.1 NM_012139 secretion regulating guanine nucleotide exchange factor SERGEF 26297 NM_012139 /// NR_104040 /// NR_104041 0007165 // signal transduction // traceable author statement /// 0032316 // regulation of Ran GTPase activity // traceable author statement /// 0032853 // positive regulation of Ran GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005087 // Ran guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220483_s_at NM_015435 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015435.1 /DEF=Homo sapiens double ring-finger protein, Dorfin (DORFIN), mRNA. /FEA=mRNA /GEN=DORFIN /PROD=dorfin /DB_XREF=gi:13491169 /UG=Hs.48320 double ring-finger protein, Dorfin /FL=gb:NM_015435.1 NM_015435 ring finger protein 19A, RBR E3 ubiquitin protein ligase RNF19A 25897 NM_001280539 /// NM_015435 /// NM_183419 /// XM_005250853 /// XM_005250854 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0006464 // cellular protein modification process // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220484_at NM_018298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018298.1 /DEF=Homo sapiens hypothetical protein FLJ11006 (FLJ11006), mRNA. /FEA=mRNA /GEN=FLJ11006 /PROD=hypothetical protein FLJ11006 /DB_XREF=gi:8922819 /UG=Hs.49344 hypothetical protein FLJ11006 /FL=gb:NM_018298.1 NM_018298 mucolipin 3 MCOLN3 55283 NM_001253693 /// NM_018298 /// XM_005271003 /// XM_006710750 /// XM_006710751 /// XM_006710752 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220485_s_at NM_018556 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018556.1 /DEF=Homo sapiens hypothetical protein SIRP-b2 (SIRP-b2), mRNA. /FEA=mRNA /GEN=SIRP-b2 /PROD=hypothetical protein SIRP-b2 /DB_XREF=gi:8924243 /UG=Hs.50716 hypothetical protein SIRP-b2 /FL=gb:AB042624.1 gb:NM_018556.1 NM_018556 signal-regulatory protein gamma SIRPG 55423 NM_001039508 /// NM_018556 /// NM_080816 /// XM_005260749 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220486_x_at NM_017698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017698.1 /DEF=Homo sapiens hypothetical protein FLJ20173 (FLJ20173), mRNA. /FEA=mRNA /GEN=FLJ20173 /PROD=hypothetical protein FLJ20173 /DB_XREF=gi:8923168 /UG=Hs.5472 hypothetical protein FLJ20173 /FL=gb:NM_017698.1 NM_017698 uncharacterized LOC101928589 /// transmembrane protein 164 LOC101928589 /// TMEM164 84187 /// 101928589 NM_017698 /// NM_032227 /// XM_005262205 /// XM_005262206 /// XM_005262208 /// XM_005262239 /// XM_006724708 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220487_at NM_018968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018968.1 /DEF=Homo sapiens syntrophin, gamma 2 (SNTG2), mRNA. /FEA=mRNA /GEN=SNTG2 /PROD=syntrophin, gamma 2 /DB_XREF=gi:9507164 /UG=Hs.65792 syntrophin, gamma 2 /FL=gb:NM_018968.1 NM_018968 syntrophin, gamma 2 SNTG2 54221 NM_018968 /// XM_006711888 /// XM_006711889 /// XM_006711890 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction 220488_s_at NM_017679 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017679.1 /DEF=Homo sapiens hypothetical protein FLJ20128 (FLJ20128), mRNA. /FEA=mRNA /GEN=FLJ20128 /PROD=hypothetical protein FLJ20128 /DB_XREF=gi:8923130 /UG=Hs.6649 hypothetical protein FLJ20128 /FL=gb:NM_017679.1 NM_017679 breast carcinoma amplified sequence 3 BCAS3 54828 NM_001099432 /// NM_017679 /// XM_005257472 /// XM_005257473 /// XM_005257474 /// XM_005257475 /// XM_005257476 /// XM_005257477 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220489_s_at NM_018565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018565.1 /DEF=Homo sapiens hypothetical protein PRO0899 (PRO0899), mRNA. /FEA=mRNA /GEN=PRO0899 /PROD=hypothetical protein PRO0899 /DB_XREF=gi:8923988 /UG=Hs.8254 hypothetical protein PRO0899 /FL=gb:AF116607.1 gb:NM_018565.1 NM_018565 serine incorporator 2 SERINC2 347735 NM_001199037 /// NM_001199038 /// NM_001199039 /// NM_018565 /// NM_178865 0006658 // phosphatidylserine metabolic process // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 220490_at NM_018565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018565.1 /DEF=Homo sapiens hypothetical protein PRO0899 (PRO0899), mRNA. /FEA=mRNA /GEN=PRO0899 /PROD=hypothetical protein PRO0899 /DB_XREF=gi:8923988 /UG=Hs.8254 hypothetical protein PRO0899 /FL=gb:AF116607.1 gb:NM_018565.1 NM_018565 serine incorporator 2 SERINC2 347735 NM_001199037 /// NM_001199038 /// NM_001199039 /// NM_018565 /// NM_178865 0006658 // phosphatidylserine metabolic process // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 220491_at NM_021175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021175.1 /DEF=Homo sapiens liver-expressed antimicrobial peptide (LEAP-1), mRNA. /FEA=mRNA /GEN=LEAP-1 /PROD=liver-expressed antimicrobial peptide /DB_XREF=gi:10863972 /UG=Hs.8821 liver-expressed antimicrobial peptide /FL=gb:AF309489.1 gb:NM_021175.1 gb:AF131292.1 NM_021175 hepcidin antimicrobial peptide HAMP 57817 NM_021175 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045179 // apical cortex // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation 220492_s_at NM_004802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004802.1 /DEF=Homo sapiens otoferlin (OTOF), mRNA. /FEA=mRNA /GEN=OTOF /PROD=otoferlin /DB_XREF=gi:4758855 /UG=Hs.91608 otoferlin /FL=gb:AF107403.1 gb:NM_004802.1 NM_004802 otoferlin OTOF 9381 NM_001287489 /// NM_004802 /// NM_194248 /// NM_194322 /// NM_194323 /// XM_005264644 0007605 // sensory perception of sound // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from sequence or structural similarity /// 0061025 // membrane fusion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from sequence or structural similarity 220493_at NM_021951 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021951.1 /DEF=Homo sapiens doublesex and mab-3 related transcription factor 1 (DMRT1), mRNA. /FEA=mRNA /GEN=DMRT1 /PROD=doublesex and mab-3 related transcription factor1 /DB_XREF=gi:11386172 /UG=Hs.98586 doublesex and mab-3 related transcription factor 1 /FL=gb:NM_021951.1 gb:AF130728.1 NM_021951 doublesex and mab-3 related transcription factor 1 DMRT1 1761 NM_021951 /// XM_006716732 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002176 // male germ cell proliferation // inferred from sequence or structural similarity /// 0003006 // developmental process involved in reproduction // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007530 // sex determination // traceable author statement /// 0007548 // sex differentiation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0008584 // male gonad development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030238 // male sex determination // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046661 // male sex differentiation // inferred from sequence or structural similarity /// 0048599 // oocyte development // inferred from electronic annotation /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220494_s_at NM_018678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018678.1 /DEF=Homo sapiens lipopolysaccharide specific response-68 protein (LSR68), mRNA. /FEA=mRNA /GEN=LSR68 /PROD=lipopolysaccharide specific response-68 protein /DB_XREF=gi:8923914 /UG=Hs.103189 lipopolysaccharide specific response-68 protein /FL=gb:AF147723.1 gb:NM_018678.1 NM_018678 220495_s_at NM_024715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024715.1 /DEF=Homo sapiens hypothetical protein FLJ22625 (FLJ22625), mRNA. /FEA=mRNA /GEN=FLJ22625 /PROD=hypothetical protein FLJ22625 /DB_XREF=gi:13376016 /UG=Hs.106534 hypothetical protein FLJ22625 /FL=gb:NM_024715.1 NM_024715 thioredoxin domain containing 15 TXNDC15 79770 NM_024715 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220496_at NM_016509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016509.1 /DEF=Homo sapiens C-type lectin-like receptor-2 (LOC51266), mRNA. /FEA=mRNA /GEN=LOC51266 /PROD=C-type lectin-like receptor-2 /DB_XREF=gi:7706060 /UG=Hs.114231 C-type lectin-like receptor-2 /FL=gb:AF124841.1 gb:NM_016509.1 NM_016509 C-type lectin domain family 1, member B CLEC1B 51266 NM_001099431 /// NM_016509 /// XM_005253382 0006952 // defense response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 220497_at NM_013249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013249.1 /DEF=Homo sapiens zinc finger protein 214 (ZNF214), mRNA. /FEA=mRNA /GEN=ZNF214 /PROD=zinc finger protein 214 /DB_XREF=gi:7019580 /UG=Hs.117134 zinc finger protein 214 /FL=gb:AF056617.1 gb:NM_013249.1 NM_013249 zinc finger protein 214 ZNF214 7761 NM_013249 /// XM_005253128 /// XM_005253129 /// XM_006718308 /// XM_006718309 /// XM_006718310 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 220498_at NM_006686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006686.2 /DEF=Homo sapiens actin-like 7B (ACTL7B), mRNA. /FEA=mRNA /GEN=ACTL7B /PROD=actin-like 7B /DB_XREF=gi:11761637 /UG=Hs.119287 actin-like 7B /FL=gb:NM_006686.2 NM_006686 actin-like 7B ACTL7B 10880 NM_006686 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement 0005200 // structural constituent of cytoskeleton // traceable author statement 220499_at NM_017559 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017559.1 /DEF=Homo sapiens hypothetical protein DKFZp434H2215 (DKFZp434H2215), mRNA. /FEA=mRNA /GEN=DKFZp434H2215 /PROD=hypothetical protein DKFZp434H2215 /DB_XREF=gi:8922137 /UG=Hs.120369 hypothetical protein DKFZp434H2215 /FL=gb:NM_017559.1 NM_017559 fibronectin type III domain containing 8 FNDC8 54752 NM_017559 /// XM_005257993 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 220500_s_at NM_007082 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007082.2 /DEF=Homo sapiens RAB, member of RAS oncogene family-like 2A (RABL2A), mRNA. /FEA=mRNA /GEN=RABL2A /PROD=RAB, member of RAS oncogene family-like 2A /DB_XREF=gi:7549818 /UG=Hs.122660 RAB, member of RAS oncogene family-like 2A /FL=gb:AF095350.1 gb:NM_007082.2 NM_007082 RAB, member of RAS oncogene family-like 2A /// RAB, member of RAS oncogene family-like 2B RABL2A /// RABL2B 11158 /// 11159 NM_001003789 /// NM_001130919 /// NM_001130920 /// NM_001130921 /// NM_001130922 /// NM_001130923 /// NM_007081 /// NM_007082 /// NM_013412 /// XM_005261899 /// XM_005261900 /// XM_005261901 /// XM_005263569 /// XM_005263570 /// XM_005263575 /// XM_005263576 /// XM_005263579 /// XM_005263582 /// XM_006712207 /// XM_006712208 /// XM_006712209 /// XM_006712210 /// XM_006712211 /// XM_006712212 /// XM_006712213 /// XM_006712214 /// XM_006712215 /// XM_006712216 /// XM_006712217 /// XM_006712218 /// XM_006712219 /// XM_006712220 /// XM_006712221 /// XM_006712222 /// XM_006724412 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 220501_at NM_006687 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006687.2 /DEF=Homo sapiens actin-like 7A (ACTL7A), mRNA. /FEA=mRNA /GEN=ACTL7A /PROD=actin-like 7A /DB_XREF=gi:11761636 /UG=Hs.123530 actin-like 7A /FL=gb:NM_006687.2 NM_006687 actin-like 7A ACTL7A 10881 NM_006687 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220502_s_at NM_022444 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022444.1 /DEF=Homo sapiens solute carrier family 13 (sodiumsulphate symporters), member 1 (SLC13A1), mRNA. /FEA=mRNA /GEN=SLC13A1 /PROD=solute carrier family 13 (sodiumsulphatesymporters), member 1 /DB_XREF=gi:11967976 /UG=Hs.124664 solute carrier family 13 (sodiumsulphate symporters), member 1 /FL=gb:NM_022444.1 gb:AF260824.1 NM_022444 solute carrier family 13 (sodium/sulfate symporter), member 1 SLC13A1 6561 NM_022444 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015382 // sodium:sulfate symporter activity // inferred from electronic annotation 220503_at AF260824 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF260824.1 /DEF=Homo sapiens renal sodiumsulfate cotransporter mRNA, complete cds. /FEA=mRNA /PROD=renal sodiumsulfate cotransporter /DB_XREF=gi:12620131 /UG=Hs.124664 solute carrier family 13 (sodiumsulphate symporters), member 1 /FL=gb:NM_022444.1 gb:AF260824.1 AF260824 solute carrier family 13 (sodium/sulfate symporter), member 1 SLC13A1 6561 NM_022444 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015382 // sodium:sulfate symporter activity // inferred from electronic annotation 220504_at NM_007035 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007035.2 /DEF=Homo sapiens keratocan (KERA), mRNA. /FEA=mRNA /GEN=KERA /PROD=keratocan /DB_XREF=gi:8659566 /UG=Hs.125750 keratocan /FL=gb:AF063301.1 gb:AF205403.1 gb:NM_007035.2 NM_007035 keratocan KERA 11081 NM_007035 0005975 // carbohydrate metabolic process // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation 220505_at NM_016349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016349.1 /DEF=Homo sapiens susceptibility protein NSG-x (LOC51198), mRNA. /FEA=mRNA /GEN=LOC51198 /PROD=susceptibility protein NSG-x /DB_XREF=gi:7705944 /UG=Hs.125775 susceptibility protein NSG-x /FL=gb:AF211119.1 gb:NM_016349.1 NM_016349 chromosome 9 open reading frame 53 C9orf53 51198 NM_016349 /// NR_024274 220506_at NM_004129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004129.1 /DEF=Homo sapiens guanylate cyclase 1, soluble, beta 2 (GUCY1B2), mRNA. /FEA=mRNA /GEN=GUCY1B2 /PROD=guanylate cyclase 1, soluble, beta 2 /DB_XREF=gi:8393506 /UG=Hs.126590 guanylate cyclase 1, soluble, beta 2 /FL=gb:AF038499.2 gb:NM_004129.1 NM_004129 guanylate cyclase 1, soluble, beta 2 (pseudogene) GUCY1B2 2974 NM_004129 /// NR_003923 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220507_s_at NM_016327 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016327.1 /DEF=Homo sapiens beta-ureidopropionase (LOC51733), mRNA. /FEA=mRNA /GEN=LOC51733 /PROD=beta-ureidopropionase /DB_XREF=gi:7706508 /UG=Hs.126926 beta-ureidopropionase /FL=gb:AB013885.1 gb:NM_016327.1 NM_016327 ureidopropionase, beta UPB1 51733 NM_016327 /// XM_005261633 /// XR_244378 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019483 // beta-alanine biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003837 // beta-ureidopropionase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220508_at NM_014406 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014406.1 /DEF=Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 3-like (KCNMB3L), mRNA. /FEA=mRNA /GEN=KCNMB3L /PROD=potassium large conductance calcium-activatedchannel, subfamily M, beta member 3-like /DB_XREF=gi:7657252 /UG=Hs.128342 potassium large conductance calcium-activated channel, subfamily M, beta member 3-like /FL=gb:NM_014406.1 NM_014406 chaperonin containing TCP1, subunit 8 (theta)-like 2 CCT8L2 150160 NM_014406 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005253 // anion channel activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015269 // calcium-activated potassium channel activity // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 220509_at NM_018605 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018605.1 /DEF=Homo sapiens hypothetical protein PRO1777 (PRO1777), mRNA. /FEA=mRNA /GEN=PRO1777 /PROD=hypothetical protein PRO1777 /DB_XREF=gi:8924078 /UG=Hs.131715 hypothetical protein PRO1777 /FL=gb:AF116667.1 gb:NM_018605.1 NM_018605 RNA binding motif protein 26 RBM26 64062 NM_001286631 /// NM_001286632 /// NM_018605 /// NM_022118 /// XM_005266491 /// XM_005266492 /// XM_005266493 /// XM_005266494 /// XM_005266496 /// XM_005266497 /// XM_005266498 /// XM_005266499 /// XM_005266501 /// XM_006719855 /// XM_006719856 /// XM_006719857 /// XM_006719858 /// XM_006719859 /// XM_006719860 0006397 // mRNA processing // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220510_at NM_020407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020407.1 /DEF=Homo sapiens Rh type B glycoprotein (RHBG), mRNA. /FEA=mRNA /GEN=RHBG /PROD=Rh type B glycoprotein /DB_XREF=gi:9966890 /UG=Hs.131835 Rh type B glycoprotein /FL=gb:AF193807.1 gb:NM_020407.1 NM_020407 Rh family, B glycoprotein (gene/pseudogene) RHBG 57127 NM_001256395 /// NM_001256396 /// NM_020407 /// NR_046115 0006810 // transport // inferred from electronic annotation /// 0015696 // ammonium transport // inferred from direct assay /// 0015696 // ammonium transport // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070634 // transepithelial ammonium transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from direct assay /// 0072488 // ammonium transmembrane transport // inferred from electronic annotation /// 0072488 // ammonium transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0014731 // spectrin-associated cytoskeleton // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from mutant phenotype 0008519 // ammonium transmembrane transporter activity // inferred from direct assay /// 0008519 // ammonium transmembrane transporter activity // inferred from sequence or structural similarity /// 0030506 // ankyrin binding // inferred from physical interaction 220511_s_at NM_024767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024767.1 /DEF=Homo sapiens hypothetical protein FLJ21120 (FLJ21120), mRNA. /FEA=mRNA /GEN=FLJ21120 /PROD=hypothetical protein FLJ21120 /DB_XREF=gi:13376110 /UG=Hs.133546 hypothetical protein FLJ21120 /FL=gb:NM_024767.1 NM_024767 DLC1 Rho GTPase activating protein DLC1 10395 NM_001164271 /// NM_006094 /// NM_024767 /// NM_182643 /// XM_005273374 /// XM_005273375 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0021575 // hindbrain morphogenesis // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction 220512_at NM_024767 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024767.1 /DEF=Homo sapiens hypothetical protein FLJ21120 (FLJ21120), mRNA. /FEA=mRNA /GEN=FLJ21120 /PROD=hypothetical protein FLJ21120 /DB_XREF=gi:13376110 /UG=Hs.133546 hypothetical protein FLJ21120 /FL=gb:NM_024767.1 NM_024767 DLC1 Rho GTPase activating protein DLC1 10395 NM_001164271 /// NM_006094 /// NM_024767 /// NM_182643 /// XM_005273374 /// XM_005273375 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0021575 // hindbrain morphogenesis // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from sequence or structural similarity /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction 220513_at NM_030568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030568.1 /DEF=Homo sapiens hypothetical protein MGC10818 (MGC10818), mRNA. /FEA=mRNA /GEN=MGC10818 /PROD=hypothetical protein MGC10818 /DB_XREF=gi:13386475 /UG=Hs.135200 hypothetical protein MGC10818 /FL=gb:BC004267.1 gb:NM_030568.1 NM_030568 KH homology domain containing 1-like KHDC1L 100129128 NM_001126063 220514_at NM_018568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018568.1 /DEF=Homo sapiens hypothetical protein PRO0943 (PRO0943), mRNA. /FEA=mRNA /GEN=PRO0943 /PROD=hypothetical protein PRO0943 /DB_XREF=gi:8923994 /UG=Hs.144799 hypothetical protein PRO0943 /FL=gb:AF116611.1 gb:NM_018568.1 NM_018568 220515_at NM_022076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022076.1 /DEF=Homo sapiens hypothetical protein IMAGE 109914 (LOC63904), mRNA. /FEA=mRNA /GEN=LOC63904 /PROD=hypothetical protein IMAGE 109914 /DB_XREF=gi:11545790 /UG=Hs.15572 hypothetical protein IMAGE 109914 /FL=gb:NM_022076.1 NM_022076 dual specificity phosphatase 21 DUSP21 63904 NM_022076 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 220516_at NM_017894 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017894.1 /DEF=Homo sapiens hypothetical protein FLJ20595 (FLJ20595), mRNA. /FEA=mRNA /GEN=FLJ20595 /PROD=hypothetical protein FLJ20595 /DB_XREF=gi:8923552 /UG=Hs.157938 hypothetical protein FLJ20595 /FL=gb:NM_017894.1 NM_017894 zinc finger and SCAN domain containing 2 ZSCAN2 54993 NM_001007072 /// NM_017894 /// NM_181877 /// XM_005254935 /// XM_006720596 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220517_at NM_018080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018080.1 /DEF=Homo sapiens hypothetical protein FLJ10381 (FLJ10381), mRNA. /FEA=mRNA /GEN=FLJ10381 /PROD=hypothetical protein FLJ10381 /DB_XREF=gi:8922393 /UG=Hs.158370 hypothetical protein FLJ10381 /FL=gb:NM_018080.1 NM_018080 vacuolar protein sorting 13 homolog C (S. cerevisiae) VPS13C 54832 NM_001018088 /// NM_017684 /// NM_018080 /// NM_020821 0070062 // extracellular vesicular exosome // inferred from direct assay 220518_at NM_024801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024801.1 /DEF=Homo sapiens hypothetical protein FLJ21551 (FLJ21551), mRNA. /FEA=mRNA /GEN=FLJ21551 /PROD=hypothetical protein FLJ21551 /DB_XREF=gi:13376176 /UG=Hs.159231 hypothetical protein FLJ21551 /FL=gb:NM_024801.1 NM_024801 ABI family, member 3 (NESH) binding protein ABI3BP 25890 NM_015429 /// XM_005247281 /// XM_005247282 /// XM_005247283 /// XM_005247284 /// XM_005247285 /// XM_005247286 /// XM_005247287 /// XM_005247288 /// XM_005247289 /// XM_005247290 /// XM_005247291 /// XM_005247293 /// XM_005247294 /// XM_005247295 /// XM_005247296 /// XM_005247297 /// XM_005247298 /// XM_005247299 /// XM_005247300 /// XM_005247301 /// XM_005247302 /// XM_005247303 /// XM_005247305 /// XM_005247306 /// XM_005247307 /// XM_005247308 /// XM_005247309 /// XM_005247310 /// XM_005247311 /// XM_005247312 /// XM_005247313 /// XM_005247314 /// XM_005247315 /// XM_005247316 /// XM_005247317 /// XM_005247318 /// XM_006713568 /// XM_006713569 /// XM_006713570 /// XM_006713571 /// XM_006713572 /// XM_006713573 /// XM_006713574 /// XM_006713575 /// XM_006713576 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 220519_s_at NM_030657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030657.1 /DEF=Homo sapiens lens intrinsic membrane protein 2 (19kD) (LIM2), mRNA. /FEA=mRNA /GEN=LIM2 /PROD=lens intrinsic membrane protein 2 (19kD) /DB_XREF=gi:13487895 /UG=Hs.162754 lens intrinsic membrane protein 2 (19kD) /FL=gb:AF340020.1 gb:NM_030657.1 NM_030657 lens intrinsic membrane protein 2, 19kDa LIM2 3982 NM_001161748 /// NM_030657 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // non-traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // non-traceable author statement /// 0031982 // vesicle // inferred from electronic annotation 0005212 // structural constituent of eye lens // inferred from electronic annotation 220520_s_at NM_017681 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017681.1 /DEF=Homo sapiens hypothetical protein FLJ20130 (FLJ20130), mRNA. /FEA=mRNA /GEN=FLJ20130 /PROD=hypothetical protein FLJ20130 /DB_XREF=gi:8923134 /UG=Hs.163629 hypothetical protein FLJ20130 /FL=gb:NM_017681.1 NM_017681 nucleoporin 62kDa C-terminal like NUP62CL 54830 NM_017681 /// NR_033676 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005643 // nuclear pore // inferred from electronic annotation 0017056 // structural constituent of nuclear pore // inferred from electronic annotation 220521_s_at NM_017974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017974.1 /DEF=Homo sapiens hypothetical protein FLJ10035 (FLJ10035), mRNA. /FEA=mRNA /GEN=FLJ10035 /PROD=hypothetical protein FLJ10035 /DB_XREF=gi:8922193 /UG=Hs.16390 hypothetical protein FLJ10035 /FL=gb:NM_017974.1 NM_017974 autophagy related 16-like 1 (S. cerevisiae) ATG16L1 55054 NM_001190266 /// NM_001190267 /// NM_017974 /// NM_030803 /// NM_198890 /// XM_005246082 /// XM_005246084 /// XM_005246086 /// XM_006712608 /// XR_241242 0000045 // autophagic vacuole assembly // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // non-traceable author statement 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 220522_at NM_012076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012076.1 /DEF=Homo sapiens crumbs (Drosophila) homolog 1 (CRB1), mRNA. /FEA=mRNA /GEN=CRB1 /PROD=crumbs (Drosophila) homolog 1 /DB_XREF=gi:6912321 /UG=Hs.169745 crumbs (Drosophila) homolog 1 /FL=gb:AF154671.1 gb:NM_012076.1 NM_012076 crumbs family member 1, photoreceptor morphogenesis associated CRB1 23418 NM_001193640 /// NM_001257965 /// NM_001257966 /// NM_012076 /// NM_201253 /// NR_047563 /// NR_047564 /// XM_006711249 /// XM_006711250 0007009 // plasma membrane organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0042462 // eye photoreceptor cell development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220523_at NM_024822 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024822.1 /DEF=Homo sapiens hypothetical protein FLJ22601 (FLJ22601), mRNA. /FEA=mRNA /GEN=FLJ22601 /PROD=hypothetical protein FLJ22601 /DB_XREF=gi:13376217 /UG=Hs.171419 hypothetical protein FLJ22601 /FL=gb:NM_024822.1 NM_024822 EF-hand domain (C-terminal) containing 2 EFHC2 80258 NM_025184 /// XM_005272671 /// XM_006724561 /// XM_006724562 0005509 // calcium ion binding // inferred from electronic annotation 220524_at NM_024823 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024823.1 /DEF=Homo sapiens hypothetical protein FLJ21596 (FLJ21596), mRNA. /FEA=mRNA /GEN=FLJ21596 /PROD=hypothetical protein FLJ21596 /DB_XREF=gi:13376219 /UG=Hs.171537 hypothetical protein FLJ21596 /FL=gb:NM_024823.1 NM_024823 erythrocyte membrane protein band 4.1 like 4B EPB41L4B 54566 NM_018424 /// NM_019114 /// XM_006717144 /// XM_006717145 /// XM_006717146 0031032 // actomyosin structure organization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 220525_s_at NM_012103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012103.1 /DEF=Homo sapiens ancient ubiquitous protein 1 (AUP1), mRNA. /FEA=mRNA /GEN=AUP1 /PROD=ancient ubiquitous protein 1 /DB_XREF=gi:6912259 /UG=Hs.173736 ancient ubiquitous protein 1 /FL=gb:AF100754.1 gb:NM_012103.1 NM_012103 ancient ubiquitous protein 1 AUP1 550 NM_012103 /// NM_181575 /// NM_181576 /// XM_005264392 /// XR_244944 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 220526_s_at NM_017971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017971.1 /DEF=Homo sapiens hypothetical protein FLJ10024 (FLJ10024), mRNA. /FEA=mRNA /GEN=FLJ10024 /PROD=hypothetical protein FLJ10024 /DB_XREF=gi:8922189 /UG=Hs.182698 hypothetical protein FLJ10024 /FL=gb:NM_017971.1 NM_017971 mitochondrial ribosomal protein L20 MRPL20 55052 NM_017971 /// XM_005244767 /// XM_005244768 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220527_at NM_017971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017971.1 /DEF=Homo sapiens hypothetical protein FLJ10024 (FLJ10024), mRNA. /FEA=mRNA /GEN=FLJ10024 /PROD=hypothetical protein FLJ10024 /DB_XREF=gi:8922189 /UG=Hs.182698 hypothetical protein FLJ10024 /FL=gb:NM_017971.1 NM_017971 mitochondrial ribosomal protein L20 MRPL20 55052 NM_017971 /// XM_005244767 /// XM_005244768 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220528_at NM_018399 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018399.1 /DEF=Homo sapiens VNN3 protein (HSA238982), mRNA. /FEA=mRNA /GEN=HSA238982 /PROD=VNN3 protein /DB_XREF=gi:9055235 /UG=Hs.183656 VNN3 protein /FL=gb:NM_018399.1 NM_018399 vanin 3 VNN3 55350 NM_001291702 /// NM_001291703 /// NM_018399 /// NM_078625 /// NR_028290 /// NR_028291 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0017159 // pantetheine hydrolase activity // non-traceable author statement 220529_at NM_024846 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024846.1 /DEF=Homo sapiens hypothetical protein FLJ11710 (FLJ11710), mRNA. /FEA=mRNA /GEN=FLJ11710 /PROD=hypothetical protein FLJ11710 /DB_XREF=gi:13376262 /UG=Hs.185084 hypothetical protein FLJ11710 /FL=gb:NM_024846.1 NM_024846 uncharacterized protein FLJ11710 FLJ11710 79904 220530_at NM_018519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018519.1 /DEF=Homo sapiens hypothetical protein PRO2266 (PRO2266), mRNA. /FEA=mRNA /GEN=PRO2266 /PROD=hypothetical protein PRO2266 /DB_XREF=gi:8924144 /UG=Hs.186874 hypothetical protein PRO2266 /FL=gb:AF119870.1 gb:NM_018519.1 NM_018519 220531_at NM_024849 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024849.1 /DEF=Homo sapiens hypothetical protein FLJ14126 (FLJ14126), mRNA. /FEA=mRNA /GEN=FLJ14126 /PROD=hypothetical protein FLJ14126 /DB_XREF=gi:13376268 /UG=Hs.188963 hypothetical protein FLJ14126 /FL=gb:NM_024849.1 NM_024849 220532_s_at NM_014020 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014020.1 /DEF=Homo sapiens LR8 protein (LR8), mRNA. /FEA=mRNA /GEN=LR8 /PROD=LR8 protein /DB_XREF=gi:7662497 /UG=Hs.190161 LR8 protein /FL=gb:AF115384.1 gb:NM_014020.1 NM_014020 transmembrane protein 176B TMEM176B 28959 NM_001101311 /// NM_001101312 /// NM_001101313 /// NM_001101314 /// NM_014020 /// XM_005249983 /// XM_006715933 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 2001199 // negative regulation of dendritic cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220533_at NM_024853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024853.1 /DEF=Homo sapiens hypothetical protein FLJ13385 (FLJ13385), mRNA. /FEA=mRNA /GEN=FLJ13385 /PROD=hypothetical protein FLJ13385 /DB_XREF=gi:13376276 /UG=Hs.190279 hypothetical protein FLJ13385 /FL=gb:NM_024853.1 NM_024853 220534_at NM_024114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024114.1 /DEF=Homo sapiens hypothetical protein MGC4827 (MGC4827), mRNA. /FEA=mRNA /GEN=MGC4827 /PROD=hypothetical protein MGC4827 /DB_XREF=gi:13129131 /UG=Hs.195715 hypothetical protein MGC4827 /FL=gb:BC001862.1 gb:NM_024114.1 NM_024114 tripartite motif-containing protein 49D1-like /// tripartite motif containing 48 /// tripartite motif containing 49D1 /// tripartite motif containing 49D2, pseudogene LOC101930235 /// TRIM48 /// TRIM49D1 /// TRIM49D2P 79097 /// 399939 /// 729384 /// 101930235 NM_001105522 /// NM_001206627 /// NM_024114 /// XM_005275713 /// XM_005275714 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220535_at NM_018088 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018088.1 /DEF=Homo sapiens hypothetical protein FLJ10408 (FLJ10408), mRNA. /FEA=mRNA /GEN=FLJ10408 /PROD=hypothetical protein FLJ10408 /DB_XREF=gi:8922410 /UG=Hs.196086 hypothetical protein FLJ10408 /FL=gb:NM_018088.1 NM_018088 family with sequence similarity 90, member A1 FAM90A1 55138 NM_018088 /// XM_005253403 /// XM_006719097 /// XM_006719098 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 220536_at NM_018228 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018228.1 /DEF=Homo sapiens hypothetical protein FLJ10811 (FLJ10811), mRNA. /FEA=mRNA /GEN=FLJ10811 /PROD=hypothetical protein FLJ10811 /DB_XREF=gi:8922685 /UG=Hs.196530 hypothetical protein FLJ10811 /FL=gb:NM_018228.1 NM_018228 vertebrae development associated VRTN 55237 NM_018228 0006313 // transposition, DNA-mediated // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0004803 // transposase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220537_at NM_017677 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017677.1 /DEF=Homo sapiens hypothetical protein FLJ20126 (FLJ20126), mRNA. /FEA=mRNA /GEN=FLJ20126 /PROD=hypothetical protein FLJ20126 /DB_XREF=gi:8923125 /UG=Hs.196568 hypothetical protein FLJ20126 /FL=gb:NM_017677.1 NM_017677 ankyrin repeat and SOCS box containing 12 /// myotubularin related protein 8 ASB12 /// MTMR8 55613 /// 142689 NM_017677 /// NM_130388 0016311 // dephosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 220538_at NM_024866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024866.1 /DEF=Homo sapiens hypothetical protein FLJ21135 (FLJ21135), mRNA. /FEA=mRNA /GEN=FLJ21135 /PROD=hypothetical protein FLJ21135 /DB_XREF=gi:13376299 /UG=Hs.196985 hypothetical protein FLJ21135 /FL=gb:NM_024866.1 NM_024866 adrenomedullin 2 ADM2 79924 NM_001253845 /// NM_024866 0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007586 // digestion // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 220539_at NM_017609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017609.1 /DEF=Homo sapiens hypothetical protein DKFZp434A1721 (DKFZp434A1721), mRNA. /FEA=mRNA /GEN=DKFZp434A1721 /PROD=hypothetical protein DKFZp434A1721 /DB_XREF=gi:8922123 /UG=Hs.199722 hypothetical protein DKFZp434A1721 /FL=gb:NM_017609.1 NM_017609 tetratricopeptide repeat domain 40 TTC40 54777 NM_001200049 /// NM_017609 /// NM_173572 220540_at NM_022358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022358.1 /DEF=Homo sapiens two pore potassium channel KT3.3 (LOC64181), mRNA. /FEA=mRNA /GEN=LOC64181 /PROD=two pore potassium channel KT3.3 /DB_XREF=gi:11641274 /UG=Hs.203845 two pore potassium channel KT3.3 /FL=gb:AF257081.1 gb:NM_022358.1 NM_022358 potassium channel, subfamily K, member 15 KCNK15 60598 NM_022358 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation 220541_at NM_021801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021801.2 /DEF=Homo sapiens matrix metalloproteinase 26 (MMP26), mRNA. /FEA=mRNA /GEN=MMP26 /PROD=matrix metalloproteinase 26 preproprotein /DB_XREF=gi:13027810 /UG=Hs.204732 matrix metalloproteinase 26 /FL=gb:NM_021801.2 gb:AF230354.1 gb:AF248646.1 gb:AF291664.1 NM_021801 matrix metallopeptidase 26 MMP26 56547 NM_021801 0006508 // proteolysis // non-traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220542_s_at NM_016583 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016583.1 /DEF=Homo sapiens LUNX protein; PLUNC (palate lung and nasal epithelium clone); tracheal epithelium enriched protein (LOC51297), mRNA. /FEA=mRNA /GEN=LOC51297 /PROD=LUNX protein; PLUNC (palate lung and nasalepithelium clone); tracheal epithelium enriched protein /DB_XREF=gi:7706118 /UG=Hs.211092 LUNX protein; PLUNC (palate lung and nasal epithelium clone); tracheal epithelium enriched protein /FL=gb:AB024937.1 gb:NM_016583.1 gb:AF172993.1 NM_016583 BPI fold containing family A, member 1 BPIFA1 51297 NM_001243193 /// NM_016583 /// NM_130852 /// XR_430298 0002376 // immune system process // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // non-traceable author statement /// 0050828 // regulation of liquid surface tension // inferred from direct assay /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 1900229 // negative regulation of single-species biofilm formation in or on host organism // inferred from mutant phenotype /// 1902305 // regulation of sodium ion transmembrane transport // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 220543_at NM_019596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019596.1 /DEF=Homo sapiens chromosome 21 open reading frame 62 (C21ORF62), mRNA. /FEA=mRNA /GEN=C21ORF62 /PROD=chromosome 21 open reading frame 62 /DB_XREF=gi:9624970 /UG=Hs.213004 chromosome 21 open reading frame 62 /FL=gb:NM_019596.1 NM_019596 chromosome 21 open reading frame 62 C21orf62 56245 NM_001162495 /// NM_001162496 /// NM_019596 220544_at NM_021733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021733.1 /DEF=Homo sapiens testis-specific kinase substrate (TSKS), mRNA. /FEA=mRNA /GEN=TSKS /PROD=testis-specific kinase substrate /DB_XREF=gi:11119429 /UG=Hs.224210 testis-specific kinase substrate /FL=gb:NM_021733.1 NM_021733 testis-specific serine kinase substrate TSKS 60385 NM_021733 /// XM_005259130 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 220545_s_at NM_021733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021733.1 /DEF=Homo sapiens testis-specific kinase substrate (TSKS), mRNA. /FEA=mRNA /GEN=TSKS /PROD=testis-specific kinase substrate /DB_XREF=gi:11119429 /UG=Hs.224210 testis-specific kinase substrate /FL=gb:NM_021733.1 NM_021733 testis-specific serine kinase substrate TSKS 60385 NM_021733 /// XM_005259130 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 220546_at NM_024891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024891.1 /DEF=Homo sapiens hypothetical protein FLJ11783 (FLJ11783), mRNA. /FEA=mRNA /GEN=FLJ11783 /PROD=hypothetical protein FLJ11783 /DB_XREF=gi:13376342 /UG=Hs.232167 hypothetical protein FLJ11783 /FL=gb:NM_024891.1 NM_024891 lysine (K)-specific methyltransferase 2A /// uncharacterized LOC101929115 KMT2A /// LOC101929115 4297 /// 101929115 NM_001197104 /// NM_005933 /// NM_024891 /// XM_006718839 /// XM_006718840 /// XR_246488 /// XR_252984 /// XR_429004 /// XR_432758 0006306 // DNA methylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032411 // positive regulation of transporter activity // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // traceable author statement /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from direct assay /// 2001040 // positive regulation of cellular response to drug // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003680 // AT DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 220547_s_at NM_019054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019054.1 /DEF=Homo sapiens hypothetical protein MGC5560 (MGC5560), mRNA. /FEA=mRNA /GEN=MGC5560 /PROD=hypothetical protein MGC5560 /DB_XREF=gi:12963480 /UG=Hs.233150 hypothetical protein MGC5560 /FL=gb:NM_019054.1 NM_019054 family with sequence similarity 35, member A FAM35A 54537 NM_019054 /// XM_005269920 /// XM_006717902 /// XM_006717903 /// XM_006717904 /// XM_006717905 /// XM_006717906 220548_at NM_006071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006071.1 /DEF=Homo sapiens polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like (PKDREJ), mRNA. /FEA=mRNA /GEN=PKDREJ /PROD=polycystic kidney disease (polycystin) and REJ(sperm receptor for egg jelly, sea urchin homolog)-like /DB_XREF=gi:5174632 /UG=Hs.241383 polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like /FL=gb:AF116458.1 gb:NM_006071.1 NM_006071 polycystin (PKD) family receptor for egg jelly PKDREJ 10343 NM_006071 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007340 // acrosome reaction // traceable author statement /// 0050982 // detection of mechanical stimulus // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // not recorded 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220549_at NM_006550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006550.1 /DEF=Homo sapiens fibrinogen silencer binding protein (FSBP), mRNA. /FEA=mRNA /GEN=FSBP /PROD=fibrinogen silencer binding protein /DB_XREF=gi:5729829 /UG=Hs.241384 fibrinogen silencer binding protein /FL=gb:AF007866.1 gb:NM_006550.1 NM_006550 fibrinogen silencer binding protein /// RAD54 homolog B (S. cerevisiae) FSBP /// RAD54B 25788 /// 100861412 NM_001205262 /// NM_001205263 /// NM_001256141 /// NM_006550 /// NM_012415 /// NM_134434 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006312 // mitotic recombination // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // traceable author statement /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015616 // DNA translocase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 220550_at NM_018007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018007.1 /DEF=Homo sapiens hypothetical protein FLJ10141 (FLJ10141), mRNA. /FEA=mRNA /GEN=FLJ10141 /PROD=hypothetical protein FLJ10141 /DB_XREF=gi:8922249 /UG=Hs.241930 hypothetical protein FLJ10141 /FL=gb:NM_018007.1 NM_018007 F-box protein 4 FBXO4 26272 NM_001297437 /// NM_012176 /// NM_033484 /// XM_005248287 /// XM_006714470 0000209 // protein polyubiquitination // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 220551_at NM_020346 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020346.1 /DEF=Homo sapiens differentiation-associated Na-dependent inorganic phosphate cotransporter (DNPI), mRNA. /FEA=mRNA /GEN=DNPI /PROD=differentiation-associated Na-dependentinorganic phosphate cotransporter /DB_XREF=gi:9966810 /UG=Hs.242821 differentiation-associated Na-dependent inorganic phosphate cotransporter /FL=gb:AB032435.1 gb:NM_020346.1 NM_020346 solute carrier family 17 (vesicular glutamate transporter), member 6 SLC17A6 57084 NM_020346 0001504 // neurotransmitter uptake // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 220552_at NM_012471 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012471.1 /DEF=Homo sapiens transient receptor potential channel 5 (TRPC5), mRNA. /FEA=mRNA /GEN=TRPC5 /PROD=transient receptor potential channel 5 /DB_XREF=gi:6912735 /UG=Hs.247868 transient receptor potential channel 5 /FL=gb:AF054568.1 gb:NM_012471.1 NM_012471 transient receptor potential cation channel, subfamily C, member 5 TRPC5 7224 NM_012471 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // traceable author statement /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from electronic annotation 220553_s_at NM_018333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018333.1 /DEF=Homo sapiens hypothetical protein FLJ11128 (FLJ11128), mRNA. /FEA=mRNA /GEN=FLJ11128 /PROD=hypothetical protein FLJ11128 /DB_XREF=gi:8922887 /UG=Hs.250477 hypothetical protein FLJ11128 /FL=gb:NM_018333.1 NM_018333 pre-mRNA processing factor 39 PRPF39 55015 NM_017922 /// NM_018333 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 220554_at NM_006672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006672.1 /DEF=Homo sapiens solute carrier family 22 (organic anion transporter), member 7 (SLC22A7), mRNA. /FEA=mRNA /GEN=SLC22A7 /PROD=solute carrier family 22 (organic aniontransporter), member 7 /DB_XREF=gi:5730048 /UG=Hs.251395 solute carrier family 22 (organic anion transporter), member 7 /FL=gb:AF097518.1 gb:NM_006672.1 NM_006672 solute carrier family 22 (organic anion transporter), member 7 SLC22A7 10864 NM_006672 /// NM_153320 /// XM_006714970 /// XM_006714971 /// XM_006714972 /// XM_006714973 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015711 // organic anion transport // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0008514 // organic anion transmembrane transporter activity // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 220555_s_at NM_024895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024895.1 /DEF=Homo sapiens hypothetical protein FLJ23209 (FLJ23209), mRNA. /FEA=mRNA /GEN=FLJ23209 /PROD=hypothetical protein FLJ23209 /DB_XREF=gi:13376348 /UG=Hs.25298 hypothetical protein FLJ23209 /FL=gb:NM_024895.1 NM_024895 PDZ domain containing 7 PDZD7 79955 NM_001195263 /// NM_024895 /// XM_005270165 /// XM_006717975 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005929 // cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220556_at NM_012069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012069.2 /DEF=Homo sapiens ATPase, (Na+)K+ transporting, beta 4 polypeptide (ATP1B4), mRNA. /FEA=mRNA /GEN=ATP1B4 /PROD=ATPase, (Na+)K+ transporting, beta 4polypeptide /DB_XREF=gi:12965168 /UG=Hs.258802 ATPase, (Na+)K+ transporting, beta 4 polypeptide /FL=gb:AF158383.2 gb:AF158384.2 gb:NM_012069.2 NM_012069 ATPase, Na+/K+ transporting, beta 4 polypeptide ATP1B4 23439 NM_001142447 /// NM_012069 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from direct assay /// 0015672 // monovalent inorganic cation transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // traceable author statement 220557_s_at NM_018026 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018026.1 /DEF=Homo sapiens hypothetical protein FLJ10209 (FLJ10209), mRNA. /FEA=mRNA /GEN=FLJ10209 /PROD=hypothetical protein FLJ10209 /DB_XREF=gi:8922284 /UG=Hs.260150 hypothetical protein FLJ10209 /FL=gb:NM_018026.1 NM_018026 phosphofurin acidic cluster sorting protein 1 PACS1 55690 NM_018026 /// XM_005274097 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030137 // COPI-coated vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction 220558_x_at NM_005705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005705.1 /DEF=Homo sapiens pan-hematopoietic expression (PHEMX), mRNA. /FEA=mRNA /GEN=PHEMX /PROD=pan-hematopoietic expression /DB_XREF=gi:5032206 /UG=Hs.271954 pan-hematopoietic expression /FL=gb:AF125569.1 gb:NM_005705.1 NM_005705 tetraspanin 32 TSPAN32 10077 NM_005705 /// NM_139022 /// NM_139024 /// XM_005252719 /// XM_005252720 /// XM_006718117 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030886 // negative regulation of myeloid dendritic cell activation // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070442 // integrin alphaIIb-beta3 complex // inferred from electronic annotation 220559_at NM_001426 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001426.2 /DEF=Homo sapiens engrailed homolog 1 (EN1), mRNA. /FEA=mRNA /GEN=EN1 /PROD=engrailed homolog 1 /DB_XREF=gi:7710118 /UG=Hs.271977 engrailed homolog 1 /FL=gb:NM_001426.2 NM_001426 engrailed homeobox 1 EN1 2019 NM_001426 0001501 // skeletal system development // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0030917 // midbrain-hindbrain boundary development // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220560_at NM_014144 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014144.1 /DEF=Homo sapiens SMS3 protein (SMS3), mRNA. /FEA=mRNA /GEN=SMS3 /PROD=SMS3 protein /DB_XREF=gi:7662662 /UG=Hs.272100 SMS3 protein /FL=gb:AB029488.1 gb:NM_014144.1 NM_014144 chromosome 11 open reading frame 21 C11orf21 29125 NM_001142946 /// NM_014144 /// NR_024621 0005737 // cytoplasm // inferred from electronic annotation 220561_at NM_016412 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016412.1 /DEF=Homo sapiens insulin-like growth factor 2, antisense (IGF2AS), mRNA. /FEA=mRNA /GEN=IGF2AS /PROD=insulin-like growth factor 2, antisense /DB_XREF=gi:7705972 /UG=Hs.272259 insulin-like growth factor 2, antisense /FL=gb:AB030733.1 gb:NM_016412.1 NM_016412 IGF2 antisense RNA IGF2-AS 51214 NM_016412 /// NR_028043 /// NR_028044 220562_at NM_017781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017781.1 /DEF=Homo sapiens hypothetical protein FLJ20359 (FLJ20359), mRNA. /FEA=mRNA /GEN=FLJ20359 /PROD=hypothetical protein FLJ20359 /DB_XREF=gi:8923331 /UG=Hs.272795 hypothetical protein FLJ20359 /FL=gb:NM_017781.1 NM_017781 cytochrome P450, family 2, subfamily W, polypeptide 1 CYP2W1 54905 NM_017781 /// XM_005249792 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220563_s_at NM_016148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016148.1 /DEF=Homo sapiens somatostatin receptor-interacting protein (SSTRIP), mRNA. /FEA=mRNA /GEN=SSTRIP /PROD=somatostatin receptor-interacting protein /DB_XREF=gi:11968151 /UG=Hs.274255 somatostatin receptor-interacting protein /FL=gb:NM_016148.1 gb:AF163302.1 NM_016148 SH3 and multiple ankyrin repeat domains 1 SHANK1 50944 NM_016148 /// XM_005258963 /// XM_006723233 /// XM_006723234 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0008306 // associative learning // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030534 // adult behavior // inferred from mutant phenotype /// 0032232 // negative regulation of actin filament bundle assembly // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from mutant phenotype /// 0035418 // protein localization to synapse // inferred from sequence or structural similarity /// 0042048 // olfactory behavior // inferred from electronic annotation /// 0046959 // habituation // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity /// 0050894 // determination of affect // inferred from mutant phenotype /// 0060013 // righting reflex // inferred from electronic annotation /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0060999 // positive regulation of dendritic spine development // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // non-traceable author statement /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060076 // excitatory synapse // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from sequence or structural similarity /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0030159 // receptor signaling complex scaffold activity // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // inferred from sequence or structural similarity /// 0031877 // somatostatin receptor binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0071532 // ankyrin repeat binding // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 220564_at NM_018363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018363.1 /DEF=Homo sapiens hypothetical protein FLJ11218 (FLJ11218), mRNA. /FEA=mRNA /GEN=FLJ11218 /PROD=hypothetical protein FLJ11218 /DB_XREF=gi:8922945 /UG=Hs.274413 hypothetical protein FLJ11218 /FL=gb:NM_018363.1 NM_018363 renalase, FAD-dependent amine oxidase RNLS 55328 NM_001031709 /// NM_018363 /// XM_005269946 /// XM_005269947 /// XM_005269948 /// XM_005269949 /// XM_005269950 0002931 // response to ischemia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071869 // response to catecholamine // inferred from electronic annotation /// 0071871 // response to epinephrine // inferred from electronic annotation /// 1902074 // response to salt // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 220565_at NM_016602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016602.1 /DEF=Homo sapiens G protein-coupled receptor 2 (GPR2), mRNA. /FEA=mRNA /GEN=GPR2 /PROD=CC chemokine receptor 10 /DB_XREF=gi:7705315 /UG=Hs.278446 G protein-coupled receptor 2 /FL=gb:AF215981.1 gb:NM_016602.1 gb:AF208237.1 NM_016602 chemokine (C-C motif) receptor 10 CCR10 2826 NM_016602 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0016493 // C-C chemokine receptor activity // inferred from electronic annotation 220566_at NM_014308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014308.1 /DEF=Homo sapiens phosphoinositide-3-kinase, regulatory subunit, polypeptide p101 (P101-PI3K), mRNA. /FEA=mRNA /GEN=P101-PI3K /PROD=phosphoinositide-3-kinase, regulatory subunit,polypeptide p101 /DB_XREF=gi:7657432 /UG=Hs.278901 phosphoinositide-3-kinase, regulatory subunit, polypeptide p101 /FL=gb:AF128881.1 gb:NM_014308.1 NM_014308 phosphoinositide-3-kinase, regulatory subunit 5 PIK3R5 23533 NM_001142633 /// NM_001251851 /// NM_001251852 /// NM_001251853 /// NM_001251855 /// NM_014308 /// XM_005256579 /// XM_005256580 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0005944 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity 0016301 // kinase activity // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from sequence or structural similarity /// 0046935 // 1-phosphatidylinositol-3-kinase regulator activity // inferred from electronic annotation 220567_at NM_016260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016260.1 /DEF=Homo sapiens zinc finger DNA binding protein Helios (LOC51173), mRNA. /FEA=mRNA /GEN=LOC51173 /PROD=zinc finger DNA binding protein Helios /DB_XREF=gi:7705910 /UG=Hs.278963 zinc finger DNA binding protein Helios /FL=gb:AF130863.1 gb:NM_016260.1 NM_016260 IKAROS family zinc finger 2 (Helios) IKZF2 22807 NM_001079526 /// NM_016260 /// XM_005246383 /// XM_005246384 /// XM_005246385 /// XM_005246386 /// XM_006712366 /// XM_006712367 /// XM_006712368 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220568_at NM_018582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018582.1 /DEF=Homo sapiens hypothetical protein PRO1483 (PRO1483), mRNA. /FEA=mRNA /GEN=PRO1483 /PROD=hypothetical protein PRO1483 /DB_XREF=gi:8924047 /UG=Hs.279694 hypothetical protein PRO1483 /FL=gb:AF116635.1 gb:NM_018582.1 NM_018582 uncharacterized LOC55448 PRO1483 55448 220569_at NM_018505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018505.1 /DEF=Homo sapiens hypothetical protein PRO1728 (PRO1728), mRNA. /FEA=mRNA /GEN=PRO1728 /PROD=hypothetical protein PRO1728 /DB_XREF=gi:8924072 /UG=Hs.283029 hypothetical protein PRO1728 /FL=gb:AF119852.1 gb:NM_018505.1 NM_018505 220570_at NM_020415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020415.2 /DEF=Homo sapiens found in inflammatory zone 3 (FIZZ3), mRNA. /FEA=mRNA /GEN=FIZZ3 /PROD=resistin /DB_XREF=gi:13435379 /UG=Hs.283091 found in inflammatory zone 3 /FL=gb:AF323081.1 gb:NM_020415.2 gb:AF205952.1 NM_020415 resistin RETN 56729 NM_001193374 /// NM_020415 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010714 // positive regulation of collagen metabolic process // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005179 // hormone activity // inferred from electronic annotation 220571_at NM_020229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020229.1 /DEF=Homo sapiens PR domain containing 11 (PRDM11), mRNA. /FEA=mRNA /GEN=PRDM11 /PROD=PR domain containing 11 /DB_XREF=gi:9910505 /UG=Hs.283097 PR domain containing 11 /FL=gb:AF275818.1 gb:NM_020229.1 NM_020229 PR domain containing 11 PRDM11 56981 NM_001256695 /// NM_001256696 /// NM_020229 /// NR_046338 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 220572_at NM_018705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018705.1 /DEF=Homo sapiens hypothetical protein DKFZp547G183 (DKFZp547G183), mRNA. /FEA=mRNA /GEN=DKFZp547G183 /PROD=hypothetical protein DKFZp547G183 /DB_XREF=gi:8922152 /UG=Hs.283631 hypothetical protein DKFZp547G183 /FL=gb:NM_018705.1 NM_018705 uncharacterized LOC100506282 LOC100506282 100506282 NM_018705 /// XR_110899 /// XR_159207 /// XR_171914 /// XR_424261 /// XR_424262 /// XR_428963 /// XR_432737 220573_at NM_022046 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022046.1 /DEF=Homo sapiens kallikrein 14 (KLK14), mRNA. /FEA=mRNA /GEN=KLK14 /PROD=kallikrein 14 /DB_XREF=gi:11545746 /UG=Hs.283925 kallikrein 14 /FL=gb:NM_022046.1 NM_022046 kallikrein-related peptidase 14 KLK14 43847 NM_022046 /// XM_006723224 /// XM_006723225 0006508 // proteolysis // inferred from direct assay /// 0009566 // fertilization // inferred from direct assay /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0048730 // epidermis morphogenesis // inferred from direct assay /// 0070684 // seminal clot liquefaction // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220574_at NM_024966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024966.1 /DEF=Homo sapiens hypothetical protein FLJ11598 (FLJ11598), mRNA. /FEA=mRNA /GEN=FLJ11598 /PROD=hypothetical protein FLJ11598 /DB_XREF=gi:13376456 /UG=Hs.287431 hypothetical protein FLJ11598 /FL=gb:NM_024966.1 NM_024966 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D SEMA6D 80031 NM_001198999 /// NM_020858 /// NM_024966 /// NM_153616 /// NM_153617 /// NM_153618 /// NM_153619 /// XM_005254685 /// XM_005254686 /// XM_005254687 /// XM_005254688 /// XM_005254689 /// XM_005254690 0006501 // C-terminal protein lipidation // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 220575_at NM_024974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024974.1 /DEF=Homo sapiens hypothetical protein FLJ11800 (FLJ11800), mRNA. /FEA=mRNA /GEN=FLJ11800 /PROD=hypothetical protein FLJ11800 /DB_XREF=gi:13376473 /UG=Hs.287456 hypothetical protein FLJ11800 /FL=gb:NM_024974.1 NM_024974 family with sequence similarity 106, member A FAM106A 80039 NM_024974 /// NR_026809 220576_at NM_024989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024989.1 /DEF=Homo sapiens hypothetical protein FLJ12377 (FLJ12377), mRNA. /FEA=mRNA /GEN=FLJ12377 /PROD=hypothetical protein FLJ12377 /DB_XREF=gi:13376493 /UG=Hs.287525 hypothetical protein FLJ12377 /FL=gb:NM_024989.1 NM_024989 post-GPI attachment to proteins 1 PGAP1 80055 NM_024989 /// XM_005246866 /// XR_427112 0006501 // C-terminal protein lipidation // traceable author statement /// 0006505 // GPI anchor metabolic process // inferred from electronic annotation /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015798 // myo-inositol transport // inferred from sequence or structural similarity /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0021871 // forebrain regionalization // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0060322 // head development // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004518 // nuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from sequence or structural similarity 220577_at NM_025006 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025006.1 /DEF=Homo sapiens hypothetical protein FLJ13373 (FLJ13373), mRNA. /FEA=mRNA /GEN=FLJ13373 /PROD=hypothetical protein FLJ13373 /DB_XREF=gi:13376522 /UG=Hs.287567 hypothetical protein FLJ13373 /FL=gb:NM_025006.1 NM_025006 GTPase, very large interferon inducible pseudogene 1 GVINP1 387751 NR_003945 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 220578_at NM_025008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025008.1 /DEF=Homo sapiens hypothetical protein FLJ13544 (FLJ13544), mRNA. /FEA=mRNA /GEN=FLJ13544 /PROD=hypothetical protein FLJ13544 /DB_XREF=gi:13376526 /UG=Hs.287581 hypothetical protein FLJ13544 /FL=gb:NM_025008.1 NM_025008 ADAMTS-like 4 ADAMTSL4 54507 NM_001288607 /// NM_001288608 /// NM_019032 /// NM_025008 /// XM_006711389 /// XM_006711390 /// XR_426786 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation 220579_at NM_025025 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025025.1 /DEF=Homo sapiens hypothetical protein FLJ14100 (FLJ14100), mRNA. /FEA=mRNA /GEN=FLJ14100 /PROD=hypothetical protein FLJ14100 /DB_XREF=gi:13376545 /UG=Hs.287623 hypothetical protein FLJ14100 /FL=gb:NM_025025.1 NM_025025 220580_at NM_025044 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025044.1 /DEF=Homo sapiens hypothetical protein FLJ22476 (FLJ22476), mRNA. /FEA=mRNA /GEN=FLJ22476 /PROD=hypothetical protein FLJ22476 /DB_XREF=gi:13376569 /UG=Hs.287696 hypothetical protein FLJ22476 /FL=gb:NM_025044.1 NM_025044 BicC family RNA binding protein 1 BICC1 80114 NM_001080512 /// XM_005270166 /// XM_005270167 /// XM_005270168 /// XM_005270169 /// XM_005270170 0007275 // multicellular organismal development // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220581_at NM_025059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025059.1 /DEF=Homo sapiens hypothetical protein FLJ23305 (FLJ23305), mRNA. /FEA=mRNA /GEN=FLJ23305 /PROD=hypothetical protein FLJ23305 /DB_XREF=gi:13376594 /UG=Hs.287738 hypothetical protein FLJ23305 /FL=gb:NM_025059.1 NM_025059 coiled-coil domain containing 170 CCDC170 80129 NM_025059 /// XM_006715568 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 220582_at NM_025071 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025071.1 /DEF=Homo sapiens hypothetical protein FLJ12190 (FLJ12190), mRNA. /FEA=mRNA /GEN=FLJ12190 /PROD=hypothetical protein FLJ12190 /DB_XREF=gi:13376614 /UG=Hs.288094 hypothetical protein FLJ12190 /FL=gb:NM_025071.1 NM_025071 220583_at NM_025086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025086.1 /DEF=Homo sapiens hypothetical protein FLJ22596 (FLJ22596), mRNA. /FEA=mRNA /GEN=FLJ22596 /PROD=hypothetical protein FLJ22596 /DB_XREF=gi:13376641 /UG=Hs.288460 hypothetical protein FLJ22596 /FL=gb:NM_025086.1 NM_025086 220584_at NM_025094 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025094.1 /DEF=Homo sapiens hypothetical protein FLJ22184 (FLJ22184), mRNA. /FEA=mRNA /GEN=FLJ22184 /PROD=hypothetical protein FLJ22184 /DB_XREF=gi:13376655 /UG=Hs.288540 hypothetical protein FLJ22184 /FL=gb:NM_025094.1 NM_025094 putative uncharacterized protein FLJ22184 FLJ22184 80164 NM_001080403 /// NM_001190467 /// NR_104345 220585_at NM_025130 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025130.1 /DEF=Homo sapiens hypothetical protein FLJ22761 (FLJ22761), mRNA. /FEA=mRNA /GEN=FLJ22761 /PROD=hypothetical protein FLJ22761 /DB_XREF=gi:13376710 /UG=Hs.288817 hypothetical protein FLJ22761 /FL=gb:NM_025130.1 NM_025130 hexokinase domain containing 1 HKDC1 80201 NM_025130 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // not recorded /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // not recorded 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded 220586_at NM_025134 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025134.1 /DEF=Homo sapiens hypothetical protein FLJ12178 (FLJ12178), mRNA. /FEA=mRNA /GEN=FLJ12178 /PROD=hypothetical protein FLJ12178 /DB_XREF=gi:13376714 /UG=Hs.288839 hypothetical protein FLJ12178 /FL=gb:NM_025134.1 NM_025134 chromodomain helicase DNA binding protein 9 CHD9 80205 NM_025134 /// XM_005256168 /// XM_005256169 /// XM_005256170 /// XM_005256171 /// XM_005256172 /// XM_005256174 /// XM_005256175 /// XM_005256176 /// XM_006721280 /// XM_006721281 /// XM_006721282 /// XM_006721283 /// XR_429731 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 220587_s_at NM_022372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022372.1 /DEF=Homo sapiens G protein beta subunit-like (GBL), mRNA. /FEA=mRNA /GEN=GBL /PROD=G protein beta subunit-like /DB_XREF=gi:11641232 /UG=Hs.29203 G protein beta subunit-like /FL=gb:NM_022372.1 NM_022372 MTOR associated protein, LST8 homolog (S. cerevisiae) MLST8 64223 NM_001199173 /// NM_001199174 /// NM_001199175 /// NM_022372 /// XM_005255475 /// XM_005255476 /// XM_005255478 /// XM_005255479 /// XM_005255480 /// XR_243294 /// XR_243295 /// XR_243296 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 220588_at NM_017843 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017843.1 /DEF=Homo sapiens hypothetical protein FLJ20495 (FLJ20495), mRNA. /FEA=mRNA /GEN=FLJ20495 /PROD=hypothetical protein FLJ20495 /DB_XREF=gi:8923453 /UG=Hs.293699 hypothetical protein FLJ20495 /FL=gb:NM_017843.1 NM_017843 breast carcinoma amplified sequence 4 BCAS4 55653 NM_001010974 /// NM_017843 /// NM_198799 0005737 // cytoplasm // inferred from electronic annotation 220589_s_at NM_018463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018463.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS028 (MDS028), mRNA. /FEA=mRNA /GEN=MDS028 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS028 /DB_XREF=gi:8923927 /UG=Hs.29647 uncharacterized hematopoietic stemprogenitor cells protein MDS028 /FL=gb:AF220048.1 gb:NM_018463.1 NM_018463 integrin alpha FG-GAP repeat containing 2 /// uncharacterized LOC100507424 ITFG2 /// LOC100507424 55846 /// 100507424 NM_018463 /// NR_038933 /// XM_005253707 /// XM_005253708 /// XM_005253709 /// XR_429017 0005515 // protein binding // inferred from electronic annotation 220590_at NM_018463 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018463.1 /DEF=Homo sapiens uncharacterized hematopoietic stemprogenitor cells protein MDS028 (MDS028), mRNA. /FEA=mRNA /GEN=MDS028 /PROD=uncharacterized hematopoietic stemprogenitorcells protein MDS028 /DB_XREF=gi:8923927 /UG=Hs.29647 uncharacterized hematopoietic stemprogenitor cells protein MDS028 /FL=gb:AF220048.1 gb:NM_018463.1 NM_018463 integrin alpha FG-GAP repeat containing 2 ITFG2 55846 NM_018463 /// XM_005253707 /// XM_005253708 /// XM_005253709 /// XR_429017 220591_s_at NM_025184 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025184.1 /DEF=Homo sapiens hypothetical protein FLJ22843 (FLJ22843), mRNA. /FEA=mRNA /GEN=FLJ22843 /PROD=hypothetical protein FLJ22843 /DB_XREF=gi:13376775 /UG=Hs.301143 hypothetical protein FLJ22843 /FL=gb:NM_025184.1 NM_025184 EF-hand domain (C-terminal) containing 2 EFHC2 80258 NM_025184 /// XM_005272671 /// XM_006724561 /// XM_006724562 0005509 // calcium ion binding // inferred from electronic annotation 220592_at NM_017950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017950.1 /DEF=Homo sapiens hypothetical protein FLJ20753 (FLJ20753), mRNA. /FEA=mRNA /GEN=FLJ20753 /PROD=hypothetical protein FLJ20753 /DB_XREF=gi:8923666 /UG=Hs.301363 hypothetical protein FLJ20753 /FL=gb:NM_017950.1 NM_017950 coiled-coil domain containing 40 CCDC40 55036 NM_001243342 /// NM_017950 /// XM_005257491 /// XM_005257492 0001947 // heart looping // inferred from mutant phenotype /// 0003341 // cilium movement // inferred from electronic annotation /// 0003351 // epithelial cilium movement // inferred from mutant phenotype /// 0003356 // regulation of cilium beat frequency // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0035469 // determination of pancreatic left/right asymmetry // inferred from mutant phenotype /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from mutant phenotype /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 220593_s_at NM_017950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017950.1 /DEF=Homo sapiens hypothetical protein FLJ20753 (FLJ20753), mRNA. /FEA=mRNA /GEN=FLJ20753 /PROD=hypothetical protein FLJ20753 /DB_XREF=gi:8923666 /UG=Hs.301363 hypothetical protein FLJ20753 /FL=gb:NM_017950.1 NM_017950 coiled-coil domain containing 40 CCDC40 55036 NM_001243342 /// NM_017950 /// XM_005257491 /// XM_005257492 0001947 // heart looping // inferred from mutant phenotype /// 0003341 // cilium movement // inferred from electronic annotation /// 0003351 // epithelial cilium movement // inferred from mutant phenotype /// 0003356 // regulation of cilium beat frequency // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0035469 // determination of pancreatic left/right asymmetry // inferred from mutant phenotype /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from mutant phenotype /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 220594_at NM_025192 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025192.1 /DEF=Homo sapiens hypothetical protein FLJ23071 (FLJ23071), mRNA. /FEA=mRNA /GEN=FLJ23071 /PROD=hypothetical protein FLJ23071 /DB_XREF=gi:13376783 /UG=Hs.301999 hypothetical protein FLJ23071 /FL=gb:NM_025192.1 NM_025192 O-linked N-acetylglucosamine (GlcNAc) transferase OGT 8473 NM_003605 /// NM_181672 /// NM_181673 /// XM_005262308 /// XM_006724714 0006110 // regulation of glycolytic process // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from direct assay /// 0006493 // protein O-linked glycosylation // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from sequence or structural similarity 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070688 // MLL5-L complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay /// 0097363 // protein O-GlcNAc transferase activity // inferred from sequence or structural similarity 220595_at NM_013377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013377.1 /DEF=Homo sapiens hypothetical protein (DKFZp434B0417), mRNA. /FEA=mRNA /GEN=DKFZp434B0417 /PROD=hypothetical protein /DB_XREF=gi:7242145 /UG=Hs.302689 hypothetical protein /FL=gb:AL133067.1 gb:NM_013377.1 NM_013377 PDZ domain containing ring finger 4 PDZRN4 29951 NM_001164595 /// NM_013377 /// XR_429094 0016567 // protein ubiquitination // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220596_at NM_015590 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015590.1 /DEF=Homo sapiens DKFZP434F1735 protein (DKFZP434F1735), mRNA. /FEA=mRNA /GEN=DKFZP434F1735 /PROD=DKFZP434F1735 protein /DB_XREF=gi:7661571 /UG=Hs.306189 DKFZP434F1735 protein /FL=gb:NM_015590.1 NM_015590 G patch domain containing 4 GPATCH4 54865 NM_015590 /// NM_017725 /// NM_182679 /// XM_005245287 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220597_s_at NM_018694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018694.1 /DEF=Homo sapiens HSVI binding protein (LOC55913), mRNA. /FEA=mRNA /GEN=LOC55913 /PROD=HSVI binding protein /DB_XREF=gi:8923906 /UG=Hs.306208 HSVI binding protein /FL=gb:AF267748.1 gb:NM_018694.1 NM_018694 ADP-ribosylation factor-like 6 interacting protein 4 ARL6IP4 51329 NM_001002251 /// NM_001002252 /// NM_001278378 /// NM_001278379 /// NM_001278380 /// NM_016638 /// NM_018694 /// NR_103512 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 220598_at NM_024110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024110.1 /DEF=Homo sapiens caspase recruitment domain protein 14 (CARD14), mRNA. /FEA=mRNA /GEN=CARD14 /PROD=caspase recruitment domain protein 14 /DB_XREF=gi:13129123 /UG=Hs.306227 caspase recruitment domain protein 14 /FL=gb:AF322642.1 gb:NM_024110.1 NM_024110 caspase recruitment domain family, member 14 CARD14 79092 NM_001257970 /// NM_024110 /// NM_052819 /// NR_047566 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016235 // aggresome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0050700 // CARD domain binding // inferred from physical interaction 220599_s_at NM_024110 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024110.1 /DEF=Homo sapiens caspase recruitment domain protein 14 (CARD14), mRNA. /FEA=mRNA /GEN=CARD14 /PROD=caspase recruitment domain protein 14 /DB_XREF=gi:13129123 /UG=Hs.306227 caspase recruitment domain protein 14 /FL=gb:AF322642.1 gb:NM_024110.1 NM_024110 caspase recruitment domain family, member 14 CARD14 79092 NM_001257970 /// NM_024110 /// NM_052819 /// NR_047566 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007250 // activation of NF-kappaB-inducing kinase activity // non-traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016235 // aggresome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0050700 // CARD domain binding // inferred from physical interaction 220600_at NM_017713 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017713.1 /DEF=Homo sapiens hypothetical protein FLJ20211 (FLJ20211), mRNA. /FEA=mRNA /GEN=FLJ20211 /PROD=hypothetical protein FLJ20211 /DB_XREF=gi:8923199 /UG=Hs.311100 hypothetical protein FLJ20211 /FL=gb:NM_017713.1 NM_017713 elongator acetyltransferase complex subunit 6 ELP6 54859 NM_001031703 /// NM_017713 /// XM_005265240 /// XM_005265241 /// XM_005265242 /// XM_005265243 /// XM_006713210 /// XM_006713211 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity 0033588 // Elongator holoenzyme complex // inferred from direct assay 220601_at NM_025187 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025187.1 /DEF=Homo sapiens hypothetical protein FLJ12076 (FLJ12076), mRNA. /FEA=mRNA /GEN=FLJ12076 /PROD=hypothetical protein FLJ12076 /DB_XREF=gi:13376777 /UG=Hs.326558 hypothetical protein FLJ12076 /FL=gb:NM_025187.1 NM_025187 chromosome 16 open reading frame 70 C16orf70 80262 NM_025187 /// XM_005256177 /// XM_005256178 /// XM_006721284 0005515 // protein binding // inferred from physical interaction 220602_s_at NM_025084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025084.1 /DEF=Homo sapiens hypothetical protein FLJ22795 (FLJ22795), mRNA. /FEA=mRNA /GEN=FLJ22795 /PROD=hypothetical protein FLJ22795 /DB_XREF=gi:13443001 /UG=Hs.330056 hypothetical protein FLJ22795 /FL=gb:NM_025084.1 NM_025084 golgin A2 pseudogene 7 /// golgin subfamily A member 2-like protein 3-like /// golgin A2 pseudogene /// golgin A2 pseudogene /// golgin A2 pseudogene GOLGA2P7 /// LOC101929479 /// LOC642423 /// LOC727751 /// LOC80154 80154 /// 388152 /// 642423 /// 727751 /// 101929479 NM_025084 /// NM_203426 /// NR_026811 /// NR_027001 /// NR_033936 /// NR_049748 /// NR_102747 /// NR_102748 /// NR_103496 /// XM_006720804 /// XM_006720805 /// XM_006720806 /// XM_006720807 /// XM_006720808 /// XM_006720809 /// XR_429594 /// XR_429595 /// XR_429596 /// XR_429597 /// XR_429598 /// XR_429599 0005794 // Golgi apparatus // inferred from electronic annotation 220603_s_at NM_018349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018349.1 /DEF=Homo sapiens hypothetical protein FLJ11175 (FLJ11175), mRNA. /FEA=mRNA /GEN=FLJ11175 /PROD=hypothetical protein FLJ11175 /DB_XREF=gi:8922916 /UG=Hs.33368 hypothetical protein FLJ11175 /FL=gb:NM_018349.1 NM_018349 multiple C2 domains, transmembrane 2 MCTP2 55784 NM_001159643 /// NM_001159644 /// NM_018349 /// XM_005254955 /// XM_005254957 /// XM_005254958 /// XM_005254959 /// XM_005254960 /// XM_006720602 /// XM_006720603 0019722 // calcium-mediated signaling // non-traceable author statement 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay 220604_x_at NM_006657 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006657.1 /DEF=Homo sapiens formiminotransferase cyclodeaminase (FTCD), mRNA. /FEA=mRNA /GEN=FTCD /PROD=formiminotransferase cyclodeaminase /DB_XREF=gi:11140814 /UG=Hs.36218 formiminotransferase cyclodeaminase /FL=gb:NM_006657.1 gb:AF289021.1 NM_006657 formimidoyltransferase cyclodeaminase FTCD 10841 NM_006657 /// NM_206965 /// XM_006723960 /// XM_006723961 /// XM_006723962 0006547 // histidine metabolic process // inferred from electronic annotation /// 0006548 // histidine catabolic process // traceable author statement /// 0006760 // folic acid-containing compound metabolic process // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019556 // histidine catabolic process to glutamate and formamide // inferred from electronic annotation /// 0019557 // histidine catabolic process to glutamate and formate // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005542 // folic acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030409 // glutamate formimidoyltransferase activity // inferred from electronic annotation /// 0030412 // formimidoyltetrahydrofolate cyclodeaminase activity // not recorded 220605_s_at NM_012237 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012237.2 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2 (SIRT2), transcript variant 1, mRNA. /FEA=mRNA /GEN=SIRT2 /PROD=sirtuin 2, isoform 1 /DB_XREF=gi:13775599 /UG=Hs.44017 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2 /FL=gb:AF083107.2 gb:NM_012237.2 NM_012237 sirtuin 2 SIRT2 22933 NM_001193286 /// NM_012237 /// NM_030593 /// NR_034146 /// XM_006723111 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000183 // chromatin silencing at rDNA // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006342 // chromatin silencing // non-traceable author statement /// 0006348 // chromatin silencing at telomere // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006471 // protein ADP-ribosylation // non-traceable author statement /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0006476 // protein deacetylation // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007096 // regulation of exit from mitosis // non-traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016458 // gene silencing // non-traceable author statement /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from sequence or structural similarity /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0034983 // peptidyl-lysine deacetylation // inferred from direct assay /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042325 // regulation of phosphorylation // non-traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0044242 // cellular lipid catabolic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045836 // positive regulation of meiosis // inferred from sequence or structural similarity /// 0045843 // negative regulation of striated muscle tissue development // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0051775 // response to redox state // non-traceable author statement /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0051987 // positive regulation of attachment of spindle microtubules to kinetochore // inferred from sequence or structural similarity /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0061433 // cellular response to caloric restriction // inferred from sequence or structural similarity /// 0070446 // negative regulation of oligodendrocyte progenitor proliferation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from mutant phenotype /// 0070933 // histone H4 deacetylation // inferred from direct assay /// 0071219 // cellular response to molecule of bacterial origin // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from sequence or structural similarity /// 0090042 // tubulin deacetylation // inferred from direct assay /// 0090042 // tubulin deacetylation // inferred from mutant phenotype /// 0090042 // tubulin deacetylation // inferred from sequence or structural similarity /// 1900119 // positive regulation of execution phase of apoptosis // inferred from sequence or structural similarity /// 1900195 // positive regulation of oocyte maturation // inferred from sequence or structural similarity /// 1900425 // negative regulation of defense response to bacterium // inferred from mutant phenotype /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 2000777 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005677 // chromatin silencing complex // non-traceable author statement /// 0005694 // chromosome // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0033010 // paranodal junction // inferred from sequence or structural similarity /// 0033270 // paranode region of axon // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043219 // lateral loop // inferred from sequence or structural similarity /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0072686 // mitotic spindle // inferred from direct assay /// 0072687 // meiotic spindle // inferred from sequence or structural similarity /// 0097386 // glial cell projection // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0017136 // NAD-dependent histone deacetylase activity // inferred from direct assay /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0033558 // protein deacetylase activity // inferred from mutant phenotype /// 0034979 // NAD-dependent protein deacetylase activity // inferred from direct assay /// 0034979 // NAD-dependent protein deacetylase activity // inferred from mutant phenotype /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042903 // tubulin deacetylase activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from direct assay /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 220606_s_at NM_020233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020233.1 /DEF=Homo sapiens x 006 protein (MDS006), mRNA. /FEA=mRNA /GEN=MDS006 /PROD=x 006 protein /DB_XREF=gi:9910423 /UG=Hs.47668 x 006 protein /FL=gb:AF168715.1 gb:NM_020233.1 NM_020233 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent ADPRM 56985 NM_020233 /// XM_005256738 /// XR_243561 /// XR_243562 0008152 // metabolic process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047631 // ADP-ribose diphosphatase activity // inferred from electronic annotation /// 0047734 // CDP-glycerol diphosphatase activity // inferred from electronic annotation 220607_x_at NM_016397 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016397.1 /DEF=Homo sapiens TH1 drosophila homolog (HSPC130), mRNA. /FEA=mRNA /GEN=HSPC130 /PROD=TH1 drosophila homolog /DB_XREF=gi:7705462 /UG=Hs.5184 TH1 drosophila homolog /FL=gb:AF161479.1 gb:NM_016397.1 NM_016397 negative elongation factor complex member C/D NELFCD 51497 NM_016397 /// NM_198976 /// XR_244142 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 220608_s_at NM_014106 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014106.1 /DEF=Homo sapiens PRO1914 protein (PRO1914), mRNA. /FEA=mRNA /GEN=PRO1914 /PROD=PRO1914 protein /DB_XREF=gi:7662624 /UG=Hs.5327 PRO1914 protein /FL=gb:AF118084.1 gb:NM_014106.1 NM_014106 Homo sapiens PRO1914 mRNA, complete cds. BC069776 220609_at NM_024651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024651.1 /DEF=Homo sapiens hypothetical protein FLJ11561 (FLJ11561), mRNA. /FEA=mRNA /GEN=FLJ11561 /PROD=hypothetical protein FLJ11561 /DB_XREF=gi:13375896 /UG=Hs.55982 hypothetical protein FLJ11561 /FL=gb:NM_024651.1 NM_024651 SUMO-interacting motifs containing 1 pseudogene LOC202181 202181 NR_026921 220610_s_at NM_006309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006309.1 /DEF=Homo sapiens leucine rich repeat (in FLII) interacting protein 2 (LRRFIP2), mRNA. /FEA=mRNA /GEN=LRRFIP2 /PROD=leucine rich repeat (in FLII) interactingprotein 2 /DB_XREF=gi:5453725 /UG=Hs.57672 leucine rich repeat (in FLII) interacting protein 2 /FL=gb:AF115509.1 gb:NM_006309.1 NM_006309 leucine rich repeat (in FLII) interacting protein 2 LRRFIP2 9209 NM_001134369 /// NM_001282691 /// NM_006309 /// NM_017724 /// XM_005265538 /// XM_005265539 /// XM_005265540 /// XM_005265550 /// XM_005265551 /// XM_005265553 /// XM_005265554 /// XM_005265555 /// XM_005265556 /// XM_005265557 /// XM_006713385 /// XM_006713386 /// XM_006713387 /// XM_006713388 /// XM_006713389 /// XM_006713390 /// XM_006713391 /// XM_006713392 /// XM_006713393 /// XM_006713394 /// XM_006713395 /// XM_006713396 /// XM_006713397 /// XM_006713398 /// XM_006713399 /// XM_006713400 /// XM_006713401 /// XM_006713402 /// XM_006713403 /// XM_006713404 0016055 // Wnt signaling pathway // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030275 // LRR domain binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 220611_at NM_021080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021080.1 /DEF=Homo sapiens disabled (Drosophila) homolog 1 (DAB1), mRNA. /FEA=mRNA /GEN=DAB1 /PROD=disabled (Drosophila) homolog 1 /DB_XREF=gi:10835268 /UG=Hs.8108 disabled (Drosophila) homolog 1 /FL=gb:NM_021080.1 gb:AF263547.1 NM_021080 Dab, reelin signal transducer, homolog 1 (Drosophila) DAB1 1600 NM_021080 0001764 // neuron migration // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007494 // midgut development // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0021517 // ventral spinal cord development // inferred from electronic annotation /// 0021589 // cerebellum structural organization // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021813 // cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration // inferred from electronic annotation /// 0021942 // radial glia guided migration of Purkinje cell // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation /// 0097477 // lateral motor column neuron migration // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation 220612_at NM_014135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014135.1 /DEF=Homo sapiens PRO0641 protein (PRO0641), mRNA. /FEA=mRNA /GEN=PRO0641 /PROD=PRO0641 protein /DB_XREF=gi:7662577 /UG=Hs.8345 PRO0641 protein /FL=gb:AF090939.1 gb:NM_014135.1 NM_014135 Homo sapiens clone HQ0641 PRO0641 mRNA, complete cds. AF090939 220613_s_at NM_017695 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017695.1 /DEF=Homo sapiens hypothetical protein FLJ20163 (FLJ20163), mRNA. /FEA=mRNA /GEN=FLJ20163 /PROD=hypothetical protein FLJ20163 /DB_XREF=gi:8923162 /UG=Hs.92254 hypothetical protein FLJ20163 /FL=gb:NM_017695.1 NM_017695 synaptotagmin-like 2 SYTL2 54843 NM_001162951 /// NM_001162952 /// NM_001162953 /// NM_001289608 /// NM_001289609 /// NM_001289610 /// NM_032379 /// NM_032943 /// NM_206927 /// NM_206928 /// NM_206929 /// NM_206930 /// XM_005274057 /// XM_005274058 /// XM_005274059 /// XM_005274060 /// XM_005274061 /// XM_005274062 /// XM_005274063 /// XM_005274066 /// XM_005274067 /// XM_006718589 /// XM_006718590 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006904 // vesicle docking involved in exocytosis // inferred from direct assay /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from mutant phenotype /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0042043 // neurexin family protein binding // inferred from sequence or structural similarity 220614_s_at NM_024694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024694.1 /DEF=Homo sapiens hypothetical protein FLJ23121 (FLJ23121), mRNA. /FEA=mRNA /GEN=FLJ23121 /PROD=hypothetical protein FLJ23121 /DB_XREF=gi:13375974 /UG=Hs.98912 hypothetical protein FLJ23121 /FL=gb:NM_024694.1 NM_024694 androglobin ADGB 79747 NM_024694 /// XM_006715566 0006508 // proteolysis // not recorded /// 0015671 // oxygen transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 220615_s_at NM_018099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018099.1 /DEF=Homo sapiens hypothetical protein FLJ10462 (FLJ10462), mRNA. /FEA=mRNA /GEN=FLJ10462 /PROD=hypothetical protein FLJ10462 /DB_XREF=gi:8922433 /UG=Hs.100895 hypothetical protein FLJ10462 /FL=gb:AL136843.1 gb:NM_018099.1 NM_018099 fatty acyl CoA reductase 2 FAR2 55711 NM_001271783 /// NM_001271784 /// NM_018099 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008611 // ether lipid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0035336 // long-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050062 // long-chain-fatty-acyl-CoA reductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0080019 // fatty-acyl-CoA reductase (alcohol-forming) activity // inferred from direct assay 220616_at NM_006448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006448.1 /DEF=Homo sapiens trinucleotide repeat containing 1 (TNRC1), mRNA. /FEA=mRNA /GEN=TNRC1 /PROD=trinucleotide repeat containing 1 /DB_XREF=gi:5453588 /UG=Hs.103315 trinucleotide repeat containing 1 /FL=gb:U80760.1 gb:NM_006448.1 NM_006448 zinc finger protein 384 ZNF384 171017 NM_001039916 /// NM_001039917 /// NM_001039918 /// NM_001039919 /// NM_001039920 /// NM_001135734 /// NM_133476 /// XM_006718963 /// XM_006718964 /// XM_006718965 /// XM_006718966 /// XM_006718967 /// XM_006718968 /// XM_006718969 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220617_s_at NM_018181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018181.1 /DEF=Homo sapiens hypothetical protein FLJ10697 (FLJ10697), mRNA. /FEA=mRNA /GEN=FLJ10697 /PROD=hypothetical protein FLJ10697 /DB_XREF=gi:8922593 /UG=Hs.104557 hypothetical protein FLJ10697 /FL=gb:NM_018181.1 NM_018181 zinc finger protein 532 ZNF532 55205 NM_018181 /// XM_005266722 /// XM_005266723 /// XM_005266724 /// XM_006722495 /// XM_006722496 /// XM_006722497 /// XM_006722498 /// XM_006722499 /// XR_430077 /// XR_430078 /// XR_430079 /// XR_430080 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220618_s_at NM_017984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017984.1 /DEF=Homo sapiens hypothetical protein FLJ10057 (FLJ10057), mRNA. /FEA=mRNA /GEN=FLJ10057 /PROD=hypothetical protein FLJ10057 /DB_XREF=gi:8922209 /UG=Hs.105191 hypothetical protein FLJ10057 /FL=gb:NM_017984.1 NM_017984 zinc finger, CW type with PWWP domain 1 ZCWPW1 55063 NM_001258008 /// NM_017984 /// XM_005250479 /// XM_005250480 /// XM_005250481 /// XM_006716035 /// XM_006716036 /// XM_006716037 /// XM_006716038 /// XM_006716039 /// XM_006716040 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220619_at NM_017783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017783.1 /DEF=Homo sapiens hypothetical protein FLJ20357 (FLJ20357), mRNA. /FEA=mRNA /GEN=FLJ20357 /PROD=hypothetical protein FLJ20361 /DB_XREF=gi:11034826 /UG=Hs.105461 hypothetical protein FLJ20357 /FL=gb:NM_017783.1 NM_017783 chromodomain helicase DNA binding protein 7 CHD7 55636 NM_017780 /// XM_005251266 /// XM_005251267 /// XM_006716459 /// XM_006716460 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007512 // adult heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008015 // blood circulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from mutant phenotype /// 0030217 // T cell differentiation // inferred from mutant phenotype /// 0030540 // female genitalia development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from mutant phenotype /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043584 // nose development // inferred from mutant phenotype /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0048806 // genitalia development // inferred from mutant phenotype /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype /// 0060021 // palate development // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from mutant phenotype /// 0060123 // regulation of growth hormone secretion // inferred from mutant phenotype /// 0060173 // limb development // inferred from mutant phenotype /// 0060324 // face development // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 220620_at NM_019060 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019060.1 /DEF=Homo sapiens NICE-1 protein (NICE-1), mRNA. /FEA=mRNA /GEN=NICE-1 /PROD=NICE-1 protein /DB_XREF=gi:9506922 /UG=Hs.110196 NICE-1 protein /FL=gb:NM_019060.1 NM_019060 cysteine-rich C-terminal 1 CRCT1 54544 NM_019060 220621_at NM_012186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012186.1 /DEF=Homo sapiens forkhead box E3 (FOXE3), mRNA. /FEA=mRNA /GEN=FOXE3 /PROD=forkhead box E3 /DB_XREF=gi:11386196 /UG=Hs.112968 forkhead box E3 /FL=gb:NM_012186.1 gb:AF275722.1 NM_012186 forkhead box E3 FOXE3 2301 NM_012186 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001654 // eye development // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006590 // thyroid hormone generation // not recorded /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007389 // pattern specification process // not recorded /// 0030878 // thyroid gland development // not recorded /// 0031069 // hair follicle morphogenesis // not recorded /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // not recorded /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0060022 // hard palate development // not recorded /// 0060023 // soft palate development // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220622_at NM_024727 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024727.1 /DEF=Homo sapiens hypothetical protein FLJ23259 (FLJ23259), mRNA. /FEA=mRNA /GEN=FLJ23259 /PROD=hypothetical protein FLJ23259 /DB_XREF=gi:13376039 /UG=Hs.114005 hypothetical protein FLJ23259 /FL=gb:NM_024727.1 NM_024727 leucine rich repeat containing 31 LRRC31 79782 NM_001277127 /// NM_001277128 /// NM_024727 0005515 // protein binding // inferred from electronic annotation 220623_s_at NM_025244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025244.1 /DEF=Homo sapiens testis specific, 10 (TSGA10), mRNA. /FEA=mRNA /GEN=TSGA10 /PROD=testis specific, 10 /DB_XREF=gi:13376857 /UG=Hs.116116 testis specific, 10 /FL=gb:AF254756.1 gb:NM_025244.1 NM_025244 testis specific, 10 TSGA10 80705 NM_025244 /// NM_182911 /// XM_005264022 /// XM_005264023 /// XM_005264024 /// XM_005264025 /// XM_005264026 /// XM_005264027 /// XM_005264029 /// XM_006712780 /// XM_006712781 /// XM_006712782 0007283 // spermatogenesis // traceable author statement /// 0030031 // cell projection assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220624_s_at NM_001422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001422.1 /DEF=Homo sapiens E74-like factor 5 (ets domain transcription factor) (ELF5), mRNA. /FEA=mRNA /GEN=ELF5 /PROD=E74-like factor 5 (ets domain transcriptionfactor) /DB_XREF=gi:4557550 /UG=Hs.11713 E74-like factor 5 (ets domain transcription factor) /FL=gb:AF049703.1 gb:NM_001422.1 gb:AF115403.1 NM_001422 E74-like factor 5 (ets domain transcription factor) ELF5 2001 NM_001243080 /// NM_001243081 /// NM_001422 /// NM_198381 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220625_s_at AF115403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF115403.1 /DEF=Homo sapiens Ets transcription factor ESE-2b mRNA, complete cds. /FEA=mRNA /PROD=Ets transcription factor ESE-2b /DB_XREF=gi:4559274 /UG=Hs.11713 E74-like factor 5 (ets domain transcription factor) /FL=gb:AF049703.1 gb:NM_001422.1 gb:AF115403.1 AF115403 E74-like factor 5 (ets domain transcription factor) ELF5 2001 NM_001243080 /// NM_001243081 /// NM_001422 /// NM_198381 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007398 // ectoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0060644 // mammary gland epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 220626_at NM_016186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016186.1 /DEF=Homo sapiens protein Z-dependent protease inhibitor precursor (LOC51156), mRNA. /FEA=mRNA /GEN=LOC51156 /PROD=protein Z-dependent protease inhibitorprecursor /DB_XREF=gi:7705878 /UG=Hs.118620 protein Z-dependent protease inhibitor precursor /FL=gb:AF181467.1 gb:NM_016186.1 NM_016186 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 SERPINA10 51156 NM_001100607 /// NM_016186 /// XM_005267733 /// XM_006720159 /// XM_006725163 /// XM_006725164 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030162 // regulation of proteolysis // not recorded /// 0060046 // regulation of acrosome reaction // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0008201 // heparin binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 220627_at NM_005492 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005492.1 /DEF=Homo sapiens cystatin 8 (cystatin-related epididymal specific) (CST8), mRNA. /FEA=mRNA /GEN=CST8 /PROD=cystatin 8 (cystatin-related epididymalspecific) /DB_XREF=gi:4885162 /UG=Hs.121602 cystatin 8 (cystatin-related epididymal specific) /FL=gb:AF059244.1 gb:NM_005492.1 NM_005492 cystatin 8 (cystatin-related epididymal specific) CST8 10047 NM_001281730 /// NM_005492 /// XM_005260639 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 220628_s_at NM_019064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019064.1 /DEF=Homo sapiens hypothetical protein (FLJ10832), mRNA. /FEA=mRNA /GEN=FLJ10832 /PROD=hypothetical protein /DB_XREF=gi:9506620 /UG=Hs.125490 hypothetical protein /FL=gb:NM_019064.1 NM_019064 sidekick cell adhesion molecule 2 SDK2 54549 NM_001144952 /// NM_019064 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220629_at NM_018722 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018722.1 /DEF=Homo sapiens BWRT protein (HSA404617), mRNA. /FEA=mRNA /GEN=HSA404617 /PROD=BWRT protein /DB_XREF=gi:10190657 /UG=Hs.127821 BWRT protein /FL=gb:NM_018722.1 NM_018722 KCNQ1 downstream neighbor (non-protein coding) KCNQ1DN 55539 NM_018722 /// NR_024627 220630_s_at NM_021797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021797.1 /DEF=Homo sapiens eosinophil chemotactic cytokine (TSA1902), mRNA. /FEA=mRNA /GEN=TSA1902 /PROD=eosinophil chemotactic cytokine /DB_XREF=gi:11141866 /UG=Hs.128814 eosinophil chemotactic cytokine /FL=gb:NM_021797.1 gb:AB025008.1 NM_021797 chitinase, acidic CHIA 27159 NM_001040623 /// NM_001258001 /// NM_001258002 /// NM_001258003 /// NM_001258004 /// NM_001258005 /// NM_021797 /// NM_201653 /// XM_006710577 0000272 // polysaccharide catabolic process // inferred from electronic annotation /// 0001101 // response to acid // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002532 // production of molecular mediator involved in inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006030 // chitin metabolic process // non-traceable author statement /// 0006032 // chitin catabolic process // inferred from direct assay /// 0006032 // chitin catabolic process // non-traceable author statement /// 0006037 // cell wall chitin metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007586 // digestion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009620 // response to fungus // traceable author statement /// 0090197 // positive regulation of chemokine secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author statement 0003796 // lysozyme activity // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0004568 // chitinase activity // non-traceable author statement /// 0008061 // chitin binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0030246 // carbohydrate binding // non-traceable author statement 220631_at NM_022353 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022353.1 /DEF=Homo sapiens putative sialoglycoprotease type 2 (LOC64172), mRNA. /FEA=mRNA /GEN=LOC64172 /PROD=putative sialoglycoprotease type 2 /DB_XREF=gi:11641264 /UG=Hs.130558 putative sialoglycoprotease type 2 /FL=gb:NM_022353.1 NM_022353 O-sialoglycoprotein endopeptidase-like 1 OSGEPL1 64172 NM_022353 /// XM_005246763 /// XM_005246764 /// XM_005246765 /// XM_005246766 /// XM_006712685 /// XM_006712686 0008033 // tRNA processing // inferred from electronic annotation /// 0070526 // threonylcarbamoyladenosine biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220632_s_at NM_013382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013382.1 /DEF=Homo sapiens putative protein O-mannosyltransferase (POMT2), mRNA. /FEA=mRNA /GEN=POMT2 /PROD=putative protein O-mannosyltransferase /DB_XREF=gi:7019494 /UG=Hs.132989 putative protein O-mannosyltransferase /FL=gb:AF105020.1 gb:NM_013382.1 NM_013382 protein-O-mannosyltransferase 2 POMT2 29954 NM_013382 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0035269 // protein O-linked mannosylation // inferred from electronic annotation /// 0097502 // mannosylation // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000030 // mannosyltransferase activity // inferred from electronic annotation /// 0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220633_s_at NM_016287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016287.1 /DEF=Homo sapiens HP1-BP74 (HP1-BP74), mRNA. /FEA=mRNA /GEN=HP1-BP74 /PROD=HP1-BP74 /DB_XREF=gi:7705416 /UG=Hs.142442 HP1-BP74 /FL=gb:AF113534.1 gb:NM_016287.1 NM_016287 heterochromatin protein 1, binding protein 3 HP1BP3 50809 NM_016287 /// XM_005245875 /// XM_005245876 /// XM_005245877 /// XM_005245878 /// XM_005245879 /// XM_005245882 /// XR_426610 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 220634_at NM_018488 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018488.1 /DEF=Homo sapiens T-box 4 (TBX4), mRNA. /FEA=mRNA /GEN=TBX4 /PROD=T-box 4 /DB_XREF=gi:8924253 /UG=Hs.143907 T-box 4 /FL=gb:AF188703.1 gb:NM_018488.1 NM_018488 T-box 4 TBX4 9496 NM_018488 /// XM_005257835 /// XM_005257836 /// XM_005257837 /// XM_005257838 0001525 // angiogenesis // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220635_at NM_014069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014069.1 /DEF=Homo sapiens SPR1 protein (SPR1), mRNA. /FEA=mRNA /GEN=SPR1 /PROD=SPR1 protein /DB_XREF=gi:7662664 /UG=Hs.146824 SPR1 protein /FL=gb:AB031480.1 gb:NM_014069.1 NM_014069 psoriasis susceptibility 1 candidate 2 PSORS1C2 170680 NM_014069 0005576 // extracellular region // inferred from electronic annotation 220636_at NM_023036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023036.1 /DEF=Homo sapiens dynein intermediate chain 2 (DNAI2), mRNA. /FEA=mRNA /GEN=DNAI2 /PROD=dynein intermediate chain 2 /DB_XREF=gi:12718865 /UG=Hs.147472 dynein intermediate chain 2 /FL=gb:NM_023036.1 NM_023036 dynein, axonemal, intermediate chain 2 DNAI2 64446 NM_001172810 /// NM_023036 /// XM_005257578 /// XR_429915 /// XR_429916 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from mutant phenotype /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0005930 // axoneme // inferred from mutant phenotype /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 220637_at NM_024785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024785.1 /DEF=Homo sapiens hypothetical protein FLJ22746 (FLJ22746), mRNA. /FEA=mRNA /GEN=FLJ22746 /PROD=hypothetical protein FLJ22746 /DB_XREF=gi:13376147 /UG=Hs.147585 hypothetical protein FLJ22746 /FL=gb:NM_024785.1 NM_024785 family with sequence similarity 124B FAM124B 79843 NM_001122779 /// NM_024785 0005515 // protein binding // inferred from physical interaction 220638_s_at NM_012116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012116.1 /DEF=Homo sapiens Cas-Br-M (murine) ectropic retroviral transforming sequence c (CBLC), mRNA. /FEA=mRNA /GEN=CBLC /PROD=Cas-Br-M (murine) ectropic retroviraltransforming sequence c /DB_XREF=gi:6912289 /UG=Hs.156637 Cas-Br-M (murine) ectropic retroviral transforming sequence c /FL=gb:AF117647.1 gb:NM_012116.1 NM_012116 Cbl proto-oncogene C, E3 ubiquitin protein ligase CBLC 23624 NM_001130852 /// NM_012116 /// XM_005258696 /// XM_005258697 /// XR_243917 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0023051 // regulation of signaling // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001784 // phosphotyrosine binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220639_at NM_024795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024795.1 /DEF=Homo sapiens hypothetical protein FLJ22800 (FLJ22800), mRNA. /FEA=mRNA /GEN=FLJ22800 /PROD=hypothetical protein FLJ22800 /DB_XREF=gi:13376165 /UG=Hs.156652 hypothetical protein FLJ22800 /FL=gb:NM_024795.1 NM_024795 transmembrane 4 L six family member 20 TM4SF20 79853 NM_024795 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220640_at NM_022048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022048.1 /DEF=Homo sapiens casein kinase 1, gamma 1 (CSNK1G1), mRNA. /FEA=mRNA /GEN=CSNK1G1 /PROD=casein kinase 1, gamma 1 /DB_XREF=gi:11545750 /UG=Hs.157777 casein kinase 1, gamma 1 /FL=gb:AB042562.1 gb:NM_022048.1 NM_022048 casein kinase 1, gamma 1 CSNK1G1 53944 NM_022048 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 220641_at NM_024505 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024505.1 /DEF=Homo sapiens NADPH oxidase, EF hand calcium-binding domain 5 (NOX5), mRNA. /FEA=mRNA /GEN=NOX5 /PROD=NADPH oxidase, EF hand calcium-binding domain 5 /DB_XREF=gi:13375637 /UG=Hs.160199 NADPH oxidase, EF hand calcium-binding domain 5 /FL=gb:AF317889.1 gb:NM_024505.1 NM_024505 NADPH oxidase, EF-hand calcium binding domain 5 NOX5 79400 NM_001184779 /// NM_001184780 /// NM_024505 /// NR_033671 /// NR_033672 0000910 // cytokinesis // non-traceable author statement /// 0001525 // angiogenesis // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0006811 // ion transport // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007340 // acrosome reaction // inferred from electronic annotation /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0010155 // regulation of proton transport // non-traceable author statement /// 0015992 // proton transport // inferred from direct assay /// 0042554 // superoxide anion generation // inferred from direct assay /// 0043012 // regulation of fusion of sperm to egg plasma membrane // non-traceable author statement /// 0050663 // cytokine secretion // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015252 // hydrogen ion channel activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // non-traceable author statement /// 0050661 // NADP binding // non-traceable author statement 220642_x_at NM_016334 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016334.1 /DEF=Homo sapiens putative G-protein coupled receptor (SH120), mRNA. /FEA=mRNA /GEN=SH120 /PROD=putative G-protein coupled receptor /DB_XREF=gi:7706703 /UG=Hs.16085 putative G-protein coupled receptor /FL=gb:BC003187.1 gb:AF132947.1 gb:U78723.1 gb:NM_016334.1 NM_016334 G protein-coupled receptor 89A /// G protein-coupled receptor 89B GPR89A /// GPR89B 51463 /// 653519 NM_001097612 /// NM_001097613 /// NM_001097616 /// NM_016334 /// NR_036541 /// XM_005277401 /// XM_005277402 /// XM_005277404 /// XM_006711377 /// XM_006711378 /// XM_006711379 /// XM_006711492 /// XM_006711493 /// XM_006711494 /// XR_248599 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044070 // regulation of anion transport // inferred from direct assay /// 0051452 // intracellular pH reduction // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0008308 // voltage-gated anion channel activity // inferred from direct assay 220643_s_at NM_018147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018147.1 /DEF=Homo sapiens hypothetical protein FLJ10582 (FLJ10582), mRNA. /FEA=mRNA /GEN=FLJ10582 /PROD=hypothetical protein FLJ10582 /DB_XREF=gi:8922535 /UG=Hs.173438 hypothetical protein FLJ10582 /FL=gb:NM_018147.1 NM_018147 Fas apoptotic inhibitory molecule FAIM 55179 NM_001033030 /// NM_001033031 /// NM_001033032 /// NM_018147 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 220644_at NM_014137 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014137.1 /DEF=Homo sapiens PRO0650 protein (PRO0650), mRNA. /FEA=mRNA /GEN=PRO0650 /PROD=PRO0650 protein /DB_XREF=gi:7662581 /UG=Hs.177258 PRO0650 protein /FL=gb:AF090941.1 gb:NM_014137.1 NM_014137 220645_at NM_017678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017678.1 /DEF=Homo sapiens hypothetical protein FLJ20127 (FLJ20127), mRNA. /FEA=mRNA /GEN=FLJ20127 /PROD=hypothetical protein FLJ20127 /DB_XREF=gi:8923128 /UG=Hs.179100 hypothetical protein FLJ20127 /FL=gb:NM_017678.1 NM_017678 neurexophilin and PC-esterase domain family, member 4 NXPE4 54827 NM_001077639 /// NM_017678 /// XM_006718865 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 220646_s_at NM_016523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016523.1 /DEF=Homo sapiens killer cell lectin-like receptor F1 (KLRF1), mRNA. /FEA=mRNA /GEN=KLRF1 /PROD=killer cell lectin-like receptor F1 /DB_XREF=gi:7705573 /UG=Hs.183125 killer cell lectin-like receptor F1 /FL=gb:AF175206.1 gb:NM_016523.1 NM_016523 killer cell lectin-like receptor subfamily F, member 1 KLRF1 51348 NM_001291822 /// NM_001291823 /// NM_016523 /// NR_120305 0007166 // cell surface receptor signaling pathway // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032393 // MHC class I receptor activity // traceable author statement 220647_s_at NM_016565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016565.1 /DEF=Homo sapiens E2IG2 protein (LOC51287), mRNA. /FEA=mRNA /GEN=LOC51287 /PROD=E2IG2 protein /DB_XREF=gi:7706098 /UG=Hs.18552 E2IG2 protein /FL=gb:AF242180.1 gb:NM_016565.1 NM_016565 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) COA4 51287 NM_016565 0005739 // mitochondrion // inferred from electronic annotation 220648_at NM_018702 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018702.1 /DEF=Homo sapiens double-stranded RNA specific adenosine deaminase (ADAR3), mRNA. /FEA=mRNA /GEN=ADAR3 /PROD=double-stranded RNA specific adenosinedeaminase /DB_XREF=gi:8922076 /UG=Hs.192731 double-stranded RNA specific adenosine deaminase /FL=gb:AF034837.1 gb:NM_018702.1 NM_018702 adenosine deaminase, RNA-specific, B2 (non-functional) ADARB2 105 NM_018702 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220649_at NM_024856 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024856.1 /DEF=Homo sapiens hypothetical protein FLJ12983 (FLJ12983), mRNA. /FEA=mRNA /GEN=FLJ12983 /PROD=hypothetical protein FLJ12983 /DB_XREF=gi:13399323 /UG=Hs.192757 hypothetical protein FLJ12983 /FL=gb:NM_024856.1 NM_024856 ATP/GTP binding protein-like 3 AGBL3 340351 NM_178563 /// XM_006715961 /// XM_006715962 /// XM_006715963 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220650_s_at NM_004594 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004594.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 5 (SLC9A5), mRNA. /FEA=mRNA /GEN=SLC9A5 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 5 /DB_XREF=gi:4759143 /UG=Hs.198295 solute carrier family 9 (sodiumhydrogen exchanger), isoform 5 /FL=gb:AF111173.1 gb:NM_004594.1 NM_004594 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 SLC9A5 6553 NM_004594 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation 220651_s_at NM_018518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018518.1 /DEF=Homo sapiens homolog of yeast MCM10; hypothetical protein PRO2249 (PRO2249), mRNA. /FEA=mRNA /GEN=PRO2249 /PROD=homolog of yeast MCM10; hypothetical proteinPRO2249 /DB_XREF=gi:8924142 /UG=Hs.198363 homolog of yeast MCM10; hypothetical protein PRO2249 /FL=gb:AB042719.1 gb:BC004876.1 gb:AF119869.1 gb:NM_018518.1 NM_018518 minichromosome maintenance complex component 10 MCM10 55388 NM_018518 /// NM_182751 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220652_at NM_018278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018278.1 /DEF=Homo sapiens hypothetical protein FLJ10933 (FLJ10933), mRNA. /FEA=mRNA /GEN=FLJ10933 /PROD=hypothetical protein FLJ10933 /DB_XREF=gi:8922780 /UG=Hs.201179 hypothetical protein FLJ10933 /FL=gb:NM_018278.1 NM_018278 kinesin family member 24 KIF24 347240 NM_194313 /// XM_005251450 /// XM_005251451 /// XM_006716764 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007019 // microtubule depolymerization // inferred from direct assay /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 220653_at NM_015363 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015363.1 /DEF=Homo sapiens zinc finger, imprinted 2 (ZIM2), mRNA. /FEA=mRNA /GEN=ZIM2 /PROD=zinc finger, imprinted 2 /DB_XREF=gi:7657696 /UG=Hs.201776 zinc finger, imprinted 2 /FL=gb:AF166122.1 gb:NM_015363.1 NM_015363 paternally expressed 3 /// zinc finger, imprinted 2 PEG3 /// ZIM2 5178 /// 23619 NM_001146184 /// NM_001146185 /// NM_001146186 /// NM_001146187 /// NM_001146326 /// NM_001146327 /// NM_006210 /// NM_015363 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 220654_at NM_021092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021092.1 /DEF=Homo sapiens pancreatic polypeptide 2 (PPY2), mRNA. /FEA=mRNA /GEN=PPY2 /PROD=pancreatic polypeptide 2 /DB_XREF=gi:11036647 /UG=Hs.20588 pancreatic polypeptide 2 /FL=gb:NM_021092.1 gb:AF222903.1 NM_021092 pancreatic polypeptide 2 PPY2 23614 NR_002181 220655_at NM_024873 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024873.1 /DEF=Homo sapiens hypothetical protein FLJ21162 (FLJ21162), mRNA. /FEA=mRNA /GEN=FLJ21162 /PROD=hypothetical protein FLJ21162 /DB_XREF=gi:13376309 /UG=Hs.208206 hypothetical protein FLJ21162 /FL=gb:NM_024873.1 NM_024873 TNFAIP3 interacting protein 3 TNIP3 79931 NM_001128843 /// NM_001244764 /// NM_024873 /// XM_006714309 0002756 // MyD88-independent toll-like receptor signaling pathway // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // inferred from direct assay /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay 0031593 // polyubiquitin binding // inferred from direct assay 220656_at NM_018527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018527.1 /DEF=Homo sapiens hypothetical protein PRO2435 (PRO2435), mRNA. /FEA=mRNA /GEN=PRO2435 /PROD=hypothetical protein PRO2435 /DB_XREF=gi:8924167 /UG=Hs.209887 hypothetical protein PRO2435 /FL=gb:AF119881.1 gb:NM_018527.1 NM_018527 220657_at NM_018143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018143.1 /DEF=Homo sapiens hypothetical protein FLJ10572 (FLJ10572), mRNA. /FEA=mRNA /GEN=FLJ10572 /PROD=hypothetical protein FLJ10572 /DB_XREF=gi:8922527 /UG=Hs.220998 hypothetical protein FLJ10572 /FL=gb:NM_018143.1 NM_018143 kelch-like family member 11 KLHL11 55175 NM_018143 0005515 // protein binding // inferred from electronic annotation 220658_s_at NM_020183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020183.1 /DEF=Homo sapiens transcription factor BMAL2 (LOC56938), mRNA. /FEA=mRNA /GEN=LOC56938 /PROD=transcription factor BMAL2 /DB_XREF=gi:9910367 /UG=Hs.222024 transcription factor BMAL2 /FL=gb:AB039921.1 gb:NM_020183.1 NM_020183 aryl hydrocarbon receptor nuclear translocator-like 2 ARNTL2 56938 NM_001248002 /// NM_001248003 /// NM_001248004 /// NM_001248005 /// NM_020183 /// XM_006719112 /// XM_006719113 /// XM_006719114 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from direct assay /// 0009649 // entrainment of circadian clock // non-traceable author statement /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 220659_s_at NM_018275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018275.1 /DEF=Homo sapiens hypothetical protein FLJ10925 (FLJ10925), mRNA. /FEA=mRNA /GEN=FLJ10925 /PROD=hypothetical protein FLJ10925 /DB_XREF=gi:8922774 /UG=Hs.23241 hypothetical protein FLJ10925 /FL=gb:AL136555.1 gb:NM_018275.1 NM_018275 chromosome 7 open reading frame 43 C7orf43 55262 NM_018275 220660_at NM_021208 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021208.1 /DEF=Homo sapiens EST-YD1 protein (EST-YD1), mRNA. /FEA=mRNA /GEN=EST-YD1 /PROD=EST-YD1 protein /DB_XREF=gi:10864018 /UG=Hs.23367 EST-YD1 protein /FL=gb:NM_021208.1 gb:AB021923.1 NM_021208 long intergenic non-protein coding RNA 474 LINC00474 58483 NM_021208 /// NR_024032 220661_s_at NM_017865 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017865.1 /DEF=Homo sapiens hypothetical protein FLJ20531 (FLJ20531), mRNA. /FEA=mRNA /GEN=FLJ20531 /PROD=hypothetical protein FLJ20531 /DB_XREF=gi:8923497 /UG=Hs.23617 hypothetical protein FLJ20531 /FL=gb:NM_017865.1 NM_017865 zinc finger protein 692 ZNF692 55657 NM_001136036 /// NM_001193328 /// NM_017865 /// XM_006711783 /// XM_006711784 /// XM_006711785 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220662_s_at NM_014571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014571.1 /DEF=Homo sapiens hairyenhancer-of-split related with YRPW motif-like (HEYL), mRNA. /FEA=mRNA /GEN=HEYL /PROD=hairyenhancer-of-split related with YRPWmotif-like /DB_XREF=gi:7657153 /UG=Hs.23823 hairyenhancer-of-split related with YRPW motif-like /FL=gb:NM_014571.1 NM_014571 hes-related family bHLH transcription factor with YRPW motif-like HEYL 26508 NM_014571 /// XM_005270745 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from sequence or structural similarity /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071773 // cellular response to BMP stimulus // inferred from electronic annotation /// 0072014 // proximal tubule development // inferred from electronic annotation /// 2000824 // negative regulation of androgen receptor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0050683 // AF-1 domain binding // inferred from physical interaction 220663_at NM_014271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014271.1 /DEF=Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), mRNA. /FEA=mRNA /GEN=IL1RAPL1 /PROD=interleukin 1 receptor accessory protein-like 1 /DB_XREF=gi:7657231 /UG=Hs.241385 interleukin 1 receptor accessory protein-like 1 /FL=gb:AF284435.1 gb:AF181284.1 gb:NM_014271.1 NM_014271 interleukin 1 receptor accessory protein-like 1 IL1RAPL1 11141 NM_014271 /// XM_005274441 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0045920 // negative regulation of exocytosis // inferred from direct assay /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045211 // postsynaptic membrane // non-traceable author statement 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019966 // interleukin-1 binding // inferred from direct assay 220664_at NM_006518 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006518.1 /DEF=Homo sapiens small proline-rich protein 2C (SPRR2C), mRNA. /FEA=mRNA /GEN=SPRR2C /PROD=small proline-rich protein 2C /DB_XREF=gi:10835253 /UG=Hs.2421 small proline-rich protein 2C /FL=gb:NM_006518.1 NM_006518 small proline-rich protein 2C (pseudogene) SPRR2C 6702 NR_003062 0008544 // epidermis development // non-traceable author statement /// 0009411 // response to UV // non-traceable author statement /// 0030216 // keratinocyte differentiation // non-traceable author statement /// 0051258 // protein polymerization // traceable author statement 0001533 // cornified envelope // inferred from electronic annotation /// 0001533 // cornified envelope // non-traceable author statement 0003676 // nucleic acid binding // traceable author statement /// 0046872 // metal ion binding // traceable author statement /// 0046983 // protein dimerization activity // traceable author statement 220665_at NM_016383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016383.1 /DEF=Homo sapiens HOM-TES-85 tumor antigen (LOC51213), mRNA. /FEA=mRNA /GEN=LOC51213 /PROD=HOM-TES-85 tumor antigen /DB_XREF=gi:7705970 /UG=Hs.242183 HOM-TES-85 tumor antigen /FL=gb:AF124430.1 gb:NM_016383.1 NM_016383 leucine zipper protein 4 LUZP4 51213 NM_016383 /// XM_005268343 0005634 // nucleus // inferred from electronic annotation 220666_at NM_018611 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018611.1 /DEF=Homo sapiens hypothetical protein PRO1966 (PRO1966), mRNA. /FEA=mRNA /GEN=PRO1966 /PROD=hypothetical protein PRO1966 /DB_XREF=gi:8924101 /UG=Hs.249270 hypothetical protein PRO1966 /FL=gb:AF116677.1 gb:NM_018611.1 NM_018611 220667_at NM_018540 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018540.1 /DEF=Homo sapiens hypothetical protein PRO2831 (PRO2831), mRNA. /FEA=mRNA /GEN=PRO2831 /PROD=hypothetical protein PRO2831 /DB_XREF=gi:8924205 /UG=Hs.250568 hypothetical protein PRO2831 /FL=gb:AF119901.1 gb:NM_018540.1 NM_018540 ubiquitin specific peptidase 49 USP49 25862 NM_001286554 /// NM_018561 0000398 // mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035616 // histone H2B conserved C-terminal lysine deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220668_s_at NM_006892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006892.1 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), mRNA. /FEA=mRNA /GEN=DNMT3B /PROD=DNA (cytosine-5-)-methyltransferase 3 beta /DB_XREF=gi:5901939 /UG=Hs.251673 DNA (cytosine-5-)-methyltransferase 3 beta /FL=gb:AF156488.1 gb:NM_006892.1 NM_006892 DNA (cytosine-5-)-methyltransferase 3 beta DNMT3B 1789 NM_001207055 /// NM_001207056 /// NM_006892 /// NM_175848 /// NM_175849 /// NM_175850 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006306 // DNA methylation // non-traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0031503 // protein complex localization // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046498 // S-adenosylhomocysteine metabolic process // inferred from electronic annotation /// 0046499 // S-adenosylmethioninamine metabolic process // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0090116 // C-5 methylation of cytosine // inferred from electronic annotation 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // inferred from direct assay /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // non-traceable author statement /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0009008 // DNA-methyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0045322 // unmethylated CpG binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051718 // DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates // inferred from electronic annotation 220669_at NM_017493 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017493.2 /DEF=Homo sapiens Hin-1 (HSHIN1), mRNA. /FEA=mRNA /GEN=HSHIN1 /PROD=Hin-1 /DB_XREF=gi:13518029 /UG=Hs.252722 Hin-1 /FL=gb:NM_017493.2 NM_017493 OTU deubiquitinase 4 OTUD4 54726 NM_001102653 /// NM_017493 /// NM_199324 /// XM_005263079 /// XM_005263080 /// XM_005263081 0006508 // proteolysis // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220670_at NM_018549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018549.1 /DEF=Homo sapiens hypothetical protein PRO3073 (PRO3073), mRNA. /FEA=mRNA /GEN=PRO3073 /PROD=hypothetical protein PRO3073 /DB_XREF=gi:8924232 /UG=Hs.258119 hypothetical protein PRO3073 /FL=gb:AF119912.1 gb:NM_018549.1 NM_018549 220671_at NM_012118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012118.1 /DEF=Homo sapiens CCR4-like (carbon catabolite repression 4, S. cerevisiae) (CCRN4L), mRNA. /FEA=mRNA /GEN=CCRN4L /PROD=CCR4-like (carbon catabolite repression 4, S.cerevisiae) /DB_XREF=gi:6912293 /UG=Hs.258586 CCR4-like (carbon catabolite repression 4, S. cerevisiae) /FL=gb:AF183961.1 gb:NM_012118.1 NM_012118 CCR4 carbon catabolite repression 4-like (S. cerevisiae) CCRN4L 25819 NM_012118 0000290 // deadenylation-dependent decapping of nuclear-transcribed mRNA // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0009991 // response to extracellular stimulus // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0048255 // mRNA stabilization // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220672_at NM_020958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020958.1 /DEF=Homo sapiens KIAA1622 protein (KIAA1622), mRNA. /FEA=mRNA /GEN=KIAA1622 /PROD=hypothetical protein MGC4163 /DB_XREF=gi:13124766 /UG=Hs.259599 KIAA1622 protein /FL=gb:BC002650.1 gb:NM_020958.1 NM_020958 protein phosphatase 4, regulatory subunit 4 PPP4R4 57718 NM_020958 /// NM_058237 /// XM_005267930 /// XM_005267931 /// XM_006720222 /// XM_006725168 /// XM_006725169 /// XM_006725170 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0080163 // regulation of protein serine/threonine phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0008287 // protein serine/threonine phosphatase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019888 // protein phosphatase regulator activity // inferred from direct assay 220673_s_at NM_020958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020958.1 /DEF=Homo sapiens KIAA1622 protein (KIAA1622), mRNA. /FEA=mRNA /GEN=KIAA1622 /PROD=hypothetical protein MGC4163 /DB_XREF=gi:13124766 /UG=Hs.259599 KIAA1622 protein /FL=gb:BC002650.1 gb:NM_020958.1 NM_020958 protein phosphatase 4, regulatory subunit 4 PPP4R4 57718 NM_020958 /// NM_058237 /// XM_005267930 /// XM_005267931 /// XM_006720222 /// XM_006725168 /// XM_006725169 /// XM_006725170 0032515 // negative regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0080163 // regulation of protein serine/threonine phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0008287 // protein serine/threonine phosphatase complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019888 // protein phosphatase regulator activity // inferred from direct assay 220674_at NM_024916 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024916.1 /DEF=Homo sapiens hypothetical protein FLJ22814 (FLJ22814), mRNA. /FEA=mRNA /GEN=FLJ22814 /PROD=hypothetical protein FLJ22814 /DB_XREF=gi:13376383 /UG=Hs.262150 hypothetical protein FLJ22814 /FL=gb:NM_024916.1 NM_024916 CD22 molecule CD22 933 NM_001185099 /// NM_001185100 /// NM_001185101 /// NM_001278417 /// NM_001771 /// NM_024916 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220675_s_at NM_025225 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025225.1 /DEF=Homo sapiens hypothetical protein dJ796I17.1 (DJ796I17.1), mRNA. /FEA=mRNA /GEN=DJ796I17.1 /PROD=hypothetical protein dJ796I17.1 /DB_XREF=gi:13376829 /UG=Hs.266738 hypothetical protein dJ796I17.1 /FL=gb:NM_025225.1 NM_025225 patatin-like phospholipase domain containing 3 PNPLA3 80339 NM_025225 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051264 // mono-olein transacylation activity // inferred from direct assay /// 0051265 // diolein transacylation activity // inferred from direct assay 220676_at NM_007037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007037.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA. /FEA=mRNA /GEN=ADAMTS8 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-8 preproprotein /DB_XREF=gi:5901889 /UG=Hs.271605 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 /FL=gb:AF060153.1 gb:NM_007037.1 NM_007037 ADAM metallopeptidase with thrombospondin type 1 motif, 8 ADAMTS8 11095 NM_007037 /// XM_006718758 0006508 // proteolysis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0009673 // low affinity phosphate transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220677_s_at NM_007037 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007037.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA. /FEA=mRNA /GEN=ADAMTS8 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-8 preproprotein /DB_XREF=gi:5901889 /UG=Hs.271605 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 /FL=gb:AF060153.1 gb:NM_007037.1 NM_007037 ADAM metallopeptidase with thrombospondin type 1 motif, 8 ADAMTS8 11095 NM_007037 /// XM_006718758 0006508 // proteolysis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0009673 // low affinity phosphate transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220678_at NM_017937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017937.1 /DEF=Homo sapiens hypothetical protein FLJ20712 (FLJ20712), mRNA. /FEA=mRNA /GEN=FLJ20712 /PROD=hypothetical protein FLJ20712 /DB_XREF=gi:8923640 /UG=Hs.272195 hypothetical protein FLJ20712 /FL=gb:NM_017937.1 NM_017937 uncharacterized FLJ20712 FLJ20712 55025 NM_017937 /// XR_108766 /// XR_113002 /// XR_171637 220679_s_at NM_004361 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004361.1 /DEF=Homo sapiens cadherin 7, type 2 (CDH7), mRNA. /FEA=mRNA /GEN=CDH7 /PROD=cadherin 7, type 2 /DB_XREF=gi:10645196 /UG=Hs.272211 cadherin 7, type 2 /FL=gb:NM_004361.1 gb:AB035301.1 NM_004361 cadherin 7, type 2 CDH7 1005 NM_004361 /// NM_033646 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220680_at NM_018211 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018211.1 /DEF=Homo sapiens hypothetical protein FLJ10770 (FLJ10770), mRNA. /FEA=mRNA /GEN=FLJ10770 /PROD=hypothetical protein FLJ10770 /DB_XREF=gi:8922655 /UG=Hs.272233 hypothetical protein FLJ10770 /FL=gb:NM_018211.1 NM_018211 ribonucleoprotein, PTB-binding 2 RAVER2 55225 NM_018211 /// NM_018716 /// XM_006710738 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220681_at NM_018280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018280.1 /DEF=Homo sapiens hypothetical protein FLJ10945 (FLJ10945), mRNA. /FEA=mRNA /GEN=FLJ10945 /PROD=hypothetical protein FLJ10945 /DB_XREF=gi:8922784 /UG=Hs.272238 hypothetical protein FLJ10945 /FL=gb:NM_018280.1 NM_018280 proline rich 34 PRR34 55267 NM_018280 220682_s_at NM_015990 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015990.1 /DEF=Homo sapiens lymphocyte activation-associated protein (LOC51088), mRNA. /FEA=mRNA /GEN=LOC51088 /PROD=lymphocyte activation-associated protein /DB_XREF=gi:10242378 /UG=Hs.272239 lymphocyte activation-associated protein /FL=gb:NM_015990.1 gb:AF123320.1 NM_015990 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 220683_at NM_015725 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015725.1 /DEF=Homo sapiens photoreceptor outer segment all-trans retinol dehydrogenase (PRRDH), mRNA. /FEA=mRNA /GEN=PRRDH /PROD=photoreceptor outer segment all-trans retinoldehydrogenase /DB_XREF=gi:7657477 /UG=Hs.272405 photoreceptor outer segment all-trans retinol dehydrogenase /FL=gb:AF229845.1 gb:NM_015725.1 NM_015725 retinol dehydrogenase 8 (all-trans) RDH8 50700 NM_015725 0001523 // retinoid metabolic process // traceable author statement /// 0006694 // steroid biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from electronic annotation 220684_at NM_013351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013351.1 /DEF=Homo sapiens T-box 21 (TBX21), mRNA. /FEA=mRNA /GEN=TBX21 /PROD=T-box 21 /DB_XREF=gi:7019548 /UG=Hs.272409 T-box 21 /FL=gb:AF093098.1 gb:NM_013351.1 gb:AF241243.2 NM_013351 T-box 21 TBX21 30009 NM_013351 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0072676 // lymphocyte migration // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 220685_at NM_017848 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017848.1 /DEF=Homo sapiens hypothetical protein FLJ20506 (FLJ20506), mRNA. /FEA=mRNA /GEN=FLJ20506 /PROD=hypothetical protein FLJ20506 /DB_XREF=gi:8923463 /UG=Hs.272803 hypothetical protein FLJ20506 /FL=gb:NM_017848.1 NM_017848 family with sequence similarity 120C FAM120C 54954 NM_017848 /// NM_198456 /// XM_005262021 /// XM_006724589 0044822 // poly(A) RNA binding // inferred from direct assay 220686_s_at NM_018068 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018068.1 /DEF=Homo sapiens hypothetical protein FLJ10351 (FLJ10351), mRNA. /FEA=mRNA /GEN=FLJ10351 /PROD=hypothetical protein FLJ10351 /DB_XREF=gi:8922369 /UG=Hs.274150 hypothetical protein FLJ10351 /FL=gb:NM_018068.1 NM_018068 piwi-like RNA-mediated gene silencing 2 PIWIL2 55124 NM_001135721 /// NM_018068 /// XM_005273550 /// XM_005273551 0000966 // RNA 5'-end processing // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005844 // polysome // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from sequence or structural similarity /// 0043186 // P granule // inferred from sequence or structural similarity /// 0071546 // pi-body // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0034584 // piRNA binding // inferred from direct assay /// 0034584 // piRNA binding // inferred from sequence or structural similarity 220687_at NM_018175 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018175.1 /DEF=Homo sapiens hypothetical protein FLJ10671 (FLJ10671), mRNA. /FEA=mRNA /GEN=FLJ10671 /PROD=hypothetical protein FLJ10671 /DB_XREF=gi:8922584 /UG=Hs.274156 hypothetical protein FLJ10671 /FL=gb:NM_018175.1 NM_018175 uncharacterized LOC101927550 LOC101927550 101927550 NR_110102 /// XR_426214 /// XR_428218 /// XR_432199 220688_s_at NM_016183 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016183.1 /DEF=Homo sapiens 60S acidic ribosomal protein PO (LOC51154), mRNA. /FEA=mRNA /GEN=LOC51154 /PROD=60S acidic ribosomal protein PO /DB_XREF=gi:7705874 /UG=Hs.274201 60S acidic ribosomal protein PO /FL=gb:AF173378.1 gb:NM_016183.1 NM_016183 mRNA turnover 4 homolog (S. cerevisiae) MRTO4 51154 NM_016183 /// XM_006710675 0042254 // ribosome biogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 220689_at NM_018055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018055.1 /DEF=Homo sapiens hypothetical protein FLJ10314 (FLJ10314), mRNA. /FEA=mRNA /GEN=FLJ10314 /PROD=hypothetical protein FLJ10314 /DB_XREF=gi:8922345 /UG=Hs.274279 hypothetical protein FLJ10314 /FL=gb:NM_018055.1 NM_018055 220690_s_at NM_015510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015510.1 /DEF=Homo sapiens DKFZP566O084 protein (DKFZP566O084), mRNA. /FEA=mRNA /GEN=DKFZP566O084 /PROD=DKFZP566O084 protein /DB_XREF=gi:7661657 /UG=Hs.278904 DKFZP566O084 protein /FL=gb:AL117567.1 gb:NM_015510.1 NM_015510 dehydrogenase/reductase (SDR family) member 7B DHRS7B 25979 NM_015510 /// XM_005256595 /// XM_005256596 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 220691_at NM_014114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014114.1 /DEF=Homo sapiens PRO0097 protein (PRO0097), mRNA. /FEA=mRNA /GEN=PRO0097 /PROD=PRO0097 protein /DB_XREF=gi:7662521 /UG=Hs.278928 PRO0097 protein /FL=gb:AF090890.1 gb:NM_014114.1 NM_014114 220692_at NM_014147 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014147.1 /DEF=Homo sapiens HSPC047 protein (HSPC047), mRNA. /FEA=mRNA /GEN=HSPC047 /PROD=HSPC047 protein /DB_XREF=gi:7661749 /UG=Hs.278943 HSPC047 protein /FL=gb:AF161532.1 gb:NM_014147.1 NM_014147 220693_at NM_014148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014148.1 /DEF=Homo sapiens HSPC048 protein (HSPC048), mRNA. /FEA=mRNA /GEN=HSPC048 /PROD=HSPC048 protein /DB_XREF=gi:7661751 /UG=Hs.278944 HSPC048 protein /FL=gb:AF161533.1 gb:NM_014148.1 NM_014148 coiled-coil domain containing 82 CCDC82 79780 NM_014148 /// NM_024725 /// XM_005274292 /// XM_005274293 /// XM_006718909 /// XM_006718910 /// XM_006718911 /// XM_006718912 220694_at NM_014152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014152.1 /DEF=Homo sapiens HSPC054 protein (HSPC054), mRNA. /FEA=mRNA /GEN=HSPC054 /PROD=HSPC054 protein /DB_XREF=gi:7661759 /UG=Hs.278946 HSPC054 protein /FL=gb:AF161539.1 gb:NM_014152.1 NM_014152 ASAP1 intronic transcript 1 (non-protein coding) ASAP1-IT1 29065 NR_002765 220695_at NM_014163 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014163.1 /DEF=Homo sapiens HSPC073 protein (HSPC073), mRNA. /FEA=mRNA /GEN=HSPC073 /PROD=HSPC073 protein /DB_XREF=gi:7661781 /UG=Hs.278948 HSPC073 protein /FL=gb:AF161558.1 gb:NM_014163.1 NM_014163 220696_at NM_014129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014129.1 /DEF=Homo sapiens PRO0478 protein (PRO0478), mRNA. /FEA=mRNA /GEN=PRO0478 /PROD=PRO0478 protein /DB_XREF=gi:7662559 /UG=Hs.279558 PRO0478 protein /FL=gb:AF090930.1 gb:NM_014129.1 NM_014129 220697_at NM_016380 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016380.1 /DEF=Homo sapiens diferentiation-related protein dif13 (LOC51212), mRNA. /FEA=mRNA /GEN=LOC51212 /PROD=diferentiation-related protein dif13 /DB_XREF=gi:7705968 /UG=Hs.279773 diferentiation-related protein dif13 /FL=gb:AF216583.1 gb:NM_016380.1 NM_016380 220698_at NM_024314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024314.1 /DEF=Homo sapiens hypothetical protein MGC4294 (MGC4294), mRNA. /FEA=mRNA /GEN=MGC4294 /PROD=hypothetical protein MGC4294 /DB_XREF=gi:13236554 /UG=Hs.280135 hypothetical protein MGC4294 /FL=gb:BC002831.1 gb:NM_024314.1 NM_024314 uncharacterized MGC4294 MGC4294 79160 XR_109628 /// XR_112170 /// XR_172327 220699_s_at NM_018517 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018517.1 /DEF=Homo sapiens hypothetical protein PRO2214 (PRO2214), mRNA. /FEA=mRNA /GEN=PRO2214 /PROD=hypothetical protein PRO2214 /DB_XREF=gi:8924135 /UG=Hs.283035 hypothetical protein PRO2214 /FL=gb:AF119867.1 gb:NM_018517.1 NM_018517 uncharacterized protein PRO2214 PRO2214 55387 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 220700_at NM_018543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018543.1 /DEF=Homo sapiens hypothetical protein PRO2859 (PRO2859), mRNA. /FEA=mRNA /GEN=PRO2859 /PROD=hypothetical protein PRO2859 /DB_XREF=gi:8924211 /UG=Hs.283044 hypothetical protein PRO2859 /FL=gb:AF119906.1 gb:NM_018543.1 NM_018543 220701_at NM_018587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018587.1 /DEF=Homo sapiens hypothetical protein PRO1617 (PRO1617), mRNA. /FEA=mRNA /GEN=PRO1617 /PROD=hypothetical protein PRO1617 /DB_XREF=gi:8924064 /UG=Hs.283057 hypothetical protein PRO1617 /FL=gb:AF116641.1 gb:NM_018587.1 NM_018587 long intergenic non-protein coding RNA 216 LINC00216 55451 220702_at NM_018616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018616.1 /DEF=Homo sapiens hypothetical protein PRO2037 (PRO2037), mRNA. /FEA=mRNA /GEN=PRO2037 /PROD=hypothetical protein PRO2037 /DB_XREF=gi:8924113 /UG=Hs.283067 hypothetical protein PRO2037 /FL=gb:AF116684.1 gb:NM_018616.1 NM_018616 220703_at NM_018470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018470.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT009 (HT009), mRNA. /FEA=mRNA /GEN=HT009 /PROD=uncharacterized hypothalamus protein HT009 /DB_XREF=gi:8923805 /UG=Hs.283652 uncharacterized hypothalamus protein HT009 /FL=gb:AF220183.1 gb:NM_018470.1 NM_018470 IDI2 antisense RNA 1 IDI2-AS1 55853 NM_018470 /// NR_024628 /// NR_024629 /// NR_027708 /// NR_027709 220704_at NM_018563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018563.1 /DEF=Homo sapiens hypothetical protein PRO0758 (PRO0758), mRNA. /FEA=mRNA /GEN=PRO0758 /PROD=hypothetical protein PRO0758 /DB_XREF=gi:8923974 /UG=Hs.283708 hypothetical protein PRO0758 /FL=gb:AF116605.1 gb:NM_018563.1 NM_018563 IKAROS family zinc finger 1 (Ikaros) IKZF1 10320 NM_001220765 /// NM_001220766 /// NM_001220767 /// NM_001220768 /// NM_001220769 /// NM_001220770 /// NM_001220771 /// NM_001220772 /// NM_001220773 /// NM_001220774 /// NM_001220775 /// NM_001220776 /// NM_001291837 /// NM_001291838 /// NM_001291839 /// NM_001291840 /// NM_001291841 /// NM_001291842 /// NM_001291843 /// NM_001291844 /// NM_001291845 /// NM_001291846 /// NM_001291847 /// NM_006060 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007498 // mesoderm development // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045660 // positive regulation of neutrophil differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220705_s_at NM_014272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014272.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 (ADAMTS7), mRNA. /FEA=mRNA /GEN=ADAMTS7 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-7 preproprotein /DB_XREF=gi:10645198 /UG=Hs.284221 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 /FL=gb:NM_014272.1 gb:AF140675.1 NM_014272 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ADAMTS7 11173 NM_014272 /// XM_005254137 /// XM_005254138 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071773 // cellular response to BMP stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220706_at NM_014272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014272.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 (ADAMTS7), mRNA. /FEA=mRNA /GEN=ADAMTS7 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-7 preproprotein /DB_XREF=gi:10645198 /UG=Hs.284221 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 /FL=gb:NM_014272.1 gb:AF140675.1 NM_014272 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ADAMTS7 11173 NM_014272 /// XM_005254137 /// XM_005254138 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071773 // cellular response to BMP stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220707_s_at NM_024955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024955.1 /DEF=Homo sapiens hypothetical protein FLJ23322 (FLJ23322), mRNA. /FEA=mRNA /GEN=FLJ23322 /PROD=hypothetical protein FLJ23322 /DB_XREF=gi:13376440 /UG=Hs.285932 hypothetical protein FLJ23322 /FL=gb:NM_024955.1 NM_024955 FAD-dependent oxidoreductase domain containing 2 FOXRED2 80020 NM_001102371 /// NM_024955 /// XM_006724320 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 220708_at NM_024961 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024961.1 /DEF=Homo sapiens hypothetical protein FLJ11370 (FLJ11370), mRNA. /FEA=mRNA /GEN=FLJ11370 /PROD=hypothetical protein FLJ11370 /DB_XREF=gi:13376452 /UG=Hs.287408 hypothetical protein FLJ11370 /FL=gb:NM_024961.1 NM_024961 220709_at NM_024967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024967.1 /DEF=Homo sapiens hypothetical protein FLJ11637 (FLJ11637), mRNA. /FEA=mRNA /GEN=FLJ11637 /PROD=hypothetical protein FLJ11637 /DB_XREF=gi:13376459 /UG=Hs.287433 hypothetical protein FLJ11637 /FL=gb:NM_024967.1 NM_024967 zinc finger protein 556 ZNF556 80032 NM_024967 /// XM_005259647 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220710_at NM_024970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024970.1 /DEF=Homo sapiens hypothetical protein FLJ11722 (FLJ11722), mRNA. /FEA=mRNA /GEN=FLJ11722 /PROD=hypothetical protein FLJ11722 /DB_XREF=gi:13376465 /UG=Hs.287444 hypothetical protein FLJ11722 /FL=gb:NM_024970.1 NM_024970 ANP32A intronic transcript 1 (non-protein coding) ANP32A-IT1 80035 NM_001040150 /// NM_024970 /// NR_026808 220711_at NM_024978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024978.1 /DEF=Homo sapiens hypothetical protein FLJ12121 (FLJ12121), mRNA. /FEA=mRNA /GEN=FLJ12121 /PROD=hypothetical protein FLJ12121 /DB_XREF=gi:13376479 /UG=Hs.287487 hypothetical protein FLJ12121 /FL=gb:NM_024978.1 NM_024978 220712_at NM_024984 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024984.1 /DEF=Homo sapiens hypothetical protein FLJ12193 (FLJ12193), mRNA. /FEA=mRNA /GEN=FLJ12193 /PROD=hypothetical protein FLJ12193 /DB_XREF=gi:13376485 /UG=Hs.287498 hypothetical protein FLJ12193 /FL=gb:NM_024984.1 NM_024984 chromosome 8 open reading frame 60 C8orf60 619426 220713_at NM_024987 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024987.1 /DEF=Homo sapiens hypothetical protein FLJ12345 (FLJ12345), mRNA. /FEA=mRNA /GEN=FLJ12345 /PROD=hypothetical protein FLJ12345 /DB_XREF=gi:13376489 /UG=Hs.287519 hypothetical protein FLJ12345 /FL=gb:NM_024987.1 NM_024987 DENN/MADD domain containing 6B DENND6B 414918 NM_001001794 /// XM_005261914 /// XM_005261915 /// XR_430477 /// XR_430478 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 220714_at NM_024504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024504.1 /DEF=Homo sapiens PR domain containing 14 (PRDM14), mRNA. /FEA=mRNA /GEN=PRDM14 /PROD=PR domain containing 14 /DB_XREF=gi:13375635 /UG=Hs.287532 PR domain containing 14 /FL=gb:AF319458.1 gb:NM_024504.1 NM_024504 PR domain containing 14 PRDM14 63978 NM_024504 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220715_at NM_024992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024992.1 /DEF=Homo sapiens hypothetical protein FLJ12547 (FLJ12547), mRNA. /FEA=mRNA /GEN=FLJ12547 /PROD=hypothetical protein FLJ12547 /DB_XREF=gi:13376495 /UG=Hs.287533 hypothetical protein FLJ12547 /FL=gb:NM_024992.1 NM_024992 220716_at NM_024994 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024994.1 /DEF=Homo sapiens hypothetical protein FLJ12595 (FLJ12595), mRNA. /FEA=mRNA /GEN=FLJ12595 /PROD=hypothetical protein FLJ12595 /DB_XREF=gi:13376499 /UG=Hs.287536 hypothetical protein FLJ12595 /FL=gb:NM_024994.1 NM_024994 excision repair cross-complementation group 8 ERCC8 1161 NM_000082 /// NM_001007233 /// NM_001007234 /// NM_001290285 0000209 // protein polyubiquitination // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0009411 // response to UV // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0010165 // response to X-ray // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003678 // DNA helicase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 220717_at NM_025003 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025003.1 /DEF=Homo sapiens hypothetical protein FLJ13166 (FLJ13166), mRNA. /FEA=mRNA /GEN=FLJ13166 /PROD=hypothetical protein FLJ13166 /DB_XREF=gi:13376516 /UG=Hs.287554 hypothetical protein FLJ13166 /FL=gb:NM_025003.1 NM_025003 ADAM metallopeptidase with thrombospondin type 1 motif, 20 ADAMTS20 80070 NM_025003 /// NM_175851 0006508 // proteolysis // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // traceable author statement 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220718_at NM_025005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025005.1 /DEF=Homo sapiens hypothetical protein FLJ13315 (FLJ13315), mRNA. /FEA=mRNA /GEN=FLJ13315 /PROD=hypothetical protein FLJ13315 /DB_XREF=gi:13376520 /UG=Hs.287563 hypothetical protein FLJ13315 /FL=gb:NM_025005.1 NM_025005 HEXA antisense RNA 1 HEXA-AS1 80072 NM_001037223 /// NM_025005 /// NR_027262 220719_at NM_025012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025012.1 /DEF=Homo sapiens hypothetical protein FLJ13769 (FLJ13769), mRNA. /FEA=mRNA /GEN=FLJ13769 /PROD=hypothetical protein FLJ13769 /DB_XREF=gi:13376532 /UG=Hs.287594 hypothetical protein FLJ13769 /FL=gb:NM_025012.1 NM_025012 220720_x_at NM_025029 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025029.1 /DEF=Homo sapiens hypothetical protein FLJ14346 (FLJ14346), mRNA. /FEA=mRNA /GEN=FLJ14346 /PROD=hypothetical protein FLJ14346 /DB_XREF=gi:13376551 /UG=Hs.287640 hypothetical protein FLJ14346 /FL=gb:NM_025029.1 NM_025029 mitotic spindle organizing protein 2B MZT2B 80097 NM_025029 /// XM_005263792 /// XM_005263795 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008274 // gamma-tubulin ring complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220721_at NM_025040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025040.1 /DEF=Homo sapiens hypothetical protein FLJ21941 (FLJ21941), mRNA. /FEA=mRNA /GEN=FLJ21941 /PROD=hypothetical protein FLJ21941 /DB_XREF=gi:13449268 /UG=Hs.287686 hypothetical protein FLJ21941 /FL=gb:NM_025040.1 NM_025040 zinc finger protein 614 ZNF614 80110 NM_025040 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220722_s_at NM_021815 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021815.1 /DEF=Homo sapiens solute carrier family 5 (choline transporter), member 7 (SLC5A7), mRNA. /FEA=mRNA /GEN=SLC5A7 /PROD=solute carrier family 5 (choline transporter),member 7 /DB_XREF=gi:11141884 /UG=Hs.287758 solute carrier family 5 (choline transporter), member 7 /FL=gb:AF276871.1 gb:NM_021815.1 gb:AB043997.1 NM_021815 solute carrier family 5 (sodium/choline cotransporter), member 7 SLC5A7 60482 NM_021815 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007271 // synaptic transmission, cholinergic // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008292 // acetylcholine biosynthetic process // inferred from mutant phenotype /// 0015871 // choline transport // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005307 // choline:sodium symporter activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from mutant phenotype /// 0015293 // symporter activity // inferred from electronic annotation /// 0033265 // choline binding // inferred from electronic annotation 220723_s_at NM_025087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025087.1 /DEF=Homo sapiens hypothetical protein FLJ21511 (FLJ21511), mRNA. /FEA=mRNA /GEN=FLJ21511 /PROD=hypothetical protein FLJ21511 /DB_XREF=gi:13376643 /UG=Hs.288462 hypothetical protein FLJ21511 /FL=gb:NM_025087.1 NM_025087 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) CWH43 80157 NM_001286791 /// NM_025087 /// XM_005248126 /// XM_006714030 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220724_at NM_025087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025087.1 /DEF=Homo sapiens hypothetical protein FLJ21511 (FLJ21511), mRNA. /FEA=mRNA /GEN=FLJ21511 /PROD=hypothetical protein FLJ21511 /DB_XREF=gi:13376643 /UG=Hs.288462 hypothetical protein FLJ21511 /FL=gb:NM_025087.1 NM_025087 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) CWH43 80157 NM_001286791 /// NM_025087 /// XM_005248126 /// XM_006714030 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220725_x_at NM_025095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025095.1 /DEF=Homo sapiens hypothetical protein FLJ23558 (FLJ23558), mRNA. /FEA=mRNA /GEN=FLJ23558 /PROD=hypothetical protein FLJ23558 /DB_XREF=gi:13376657 /UG=Hs.288552 hypothetical protein FLJ23558 /FL=gb:NM_025095.1 NM_025095 dynein, axonemal, heavy chain 3 DNAH3 55567 NM_017539 /// XM_006721062 0001539 // cilium or flagellum-dependent cell motility // non-traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 220726_at NM_025100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025100.1 /DEF=Homo sapiens hypothetical protein FLJ12294 (FLJ12294), mRNA. /FEA=mRNA /GEN=FLJ12294 /PROD=hypothetical protein FLJ12294 /DB_XREF=gi:13376666 /UG=Hs.288584 hypothetical protein FLJ12294 /FL=gb:NM_025100.1 NM_025100 220727_at NM_021161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021161.1 /DEF=Homo sapiens potassium channel, subfamily K, member 10 (KCNK10), mRNA. /FEA=mRNA /GEN=KCNK10 /PROD=potassium channel, subfamily K, member 10 /DB_XREF=gi:10863960 /UG=Hs.288618 potassium channel, subfamily K, member 10 /FL=gb:AF279890.1 gb:NM_021161.1 NM_021161 potassium channel, subfamily K, member 10 KCNK10 54207 NM_021161 /// NM_138317 /// NM_138318 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 220728_at NM_025120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025120.1 /DEF=Homo sapiens hypothetical protein FLJ13480 (FLJ13480), mRNA. /FEA=mRNA /GEN=FLJ13480 /PROD=hypothetical protein FLJ13480 /DB_XREF=gi:13376698 /UG=Hs.288734 hypothetical protein FLJ13480 /FL=gb:NM_025120.1 NM_025120 220729_at NM_014092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014092.1 /DEF=Homo sapiens PRO1575 protein (PRO1575), mRNA. /FEA=mRNA /GEN=PRO1575 /PROD=PRO1575 protein /DB_XREF=gi:7662595 /UG=Hs.288840 PRO1575 protein /FL=gb:AF118066.1 gb:NM_014092.1 NM_014092 Homo sapiens PRO1575 mRNA, complete cds. BC069739 220730_at NM_025148 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025148.1 /DEF=Homo sapiens hypothetical protein FLJ12986 (FLJ12986), mRNA. /FEA=mRNA /GEN=FLJ12986 /PROD=hypothetical protein FLJ12986 /DB_XREF=gi:13376738 /UG=Hs.288955 hypothetical protein FLJ12986 /FL=gb:NM_025148.1 NM_025148 SubName: Full=Uncharacterized protein; /// uncharacterized LOC642533 /// DQ583205 /// LOC642533 /// ZNF778 642533 XR_172185 /// XR_424748 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220731_s_at NM_018090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018090.1 /DEF=Homo sapiens hypothetical protein FLJ10420 (FLJ10420), mRNA. /FEA=mRNA /GEN=FLJ10420 /PROD=hypothetical protein FLJ10420 /DB_XREF=gi:8922415 /UG=Hs.289087 hypothetical protein FLJ10420 /FL=gb:NM_018090.1 NM_018090 NECAP endocytosis associated 2 NECAP2 55707 NM_001145277 /// NM_001145278 /// NM_018090 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030125 // clathrin vesicle coat // inferred from sequence or structural similarity /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 220732_at NM_025170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025170.2 /DEF=Homo sapiens hypothetical protein FLJ12987 (FLJ12987), mRNA. /FEA=mRNA /GEN=FLJ12987 /PROD=hypothetical protein FLJ12987 /DB_XREF=gi:13489104 /UG=Hs.296730 hypothetical protein FLJ12987 /FL=gb:NM_025170.2 NM_025170 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 PREX2 80243 NM_024870 /// NM_025170 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay 220733_at NM_022042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022042.1 /DEF=Homo sapiens solute carrier family 26 (sulfate transporter), member 1 (SLC26A1), mRNA. /FEA=mRNA /GEN=SLC26A1 /PROD=solute carrier family 26 (sulfate transporter),member 1 /DB_XREF=gi:11545740 /UG=Hs.302008 solute carrier family 26 (sulfate transporter), member 1 /FL=gb:AF297659.2 gb:NM_022042.1 NM_022042 solute carrier family 26 (anion exchanger), member 1 SLC26A1 10861 NM_022042 /// NM_134425 /// NM_213613 /// XM_006713856 /// XM_006713857 /// XM_006713858 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from sequence or structural similarity /// 0008272 // sulfate transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from sequence or structural similarity /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from sequence or structural similarity /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from sequence or structural similarity /// 0019531 // oxalate transmembrane transporter activity // inferred from sequence or structural similarity 220734_s_at NM_030575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030575.1 /DEF=Homo sapiens hypothetical protein MGC10334 (MGC10334), mRNA. /FEA=mRNA /GEN=MGC10334 /PROD=hypothetical protein MGC10334 /DB_XREF=gi:13386487 /UG=Hs.302446 hypothetical protein MGC10334 /FL=gb:BC004366.1 gb:NM_030575.1 NM_030575 ceramide-1-phosphate transfer protein CPTP 80772 NM_001029885 /// XM_005244801 /// XM_005244802 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0046836 // glycolipid transport // inferred from direct assay /// 1902389 // ceramide 1-phosphate transport // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from direct assay /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0017089 // glycolipid transporter activity // inferred from electronic annotation /// 0051861 // glycolipid binding // inferred from electronic annotation /// 1902387 // ceramide 1-phosphate binding // inferred from direct assay /// 1902388 // ceramide 1-phosphate transporter activity // inferred from direct assay 220735_s_at NM_020654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020654.1 /DEF=Homo sapiens sentrinSUMO-specific protease (SENP7), mRNA. /FEA=mRNA /GEN=SENP7 /PROD=sentrinSUMO-specific protease /DB_XREF=gi:10190689 /UG=Hs.30443 sentrinSUMO-specific protease /FL=gb:NM_020654.1 gb:AF217504.1 NM_020654 SUMO1/sentrin specific peptidase 7 SENP7 57337 NM_001077203 /// NM_001282801 /// NM_001282802 /// NM_001282803 /// NM_001282804 /// NM_020654 /// XM_005247662 /// XM_006713713 0006508 // proteolysis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220736_at NM_025243 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025243.1 /DEF=Homo sapiens solute carrier (SLC19A3), mRNA. /FEA=mRNA /GEN=SLC19A3 /PROD=solute carrier /DB_XREF=gi:13376855 /UG=Hs.306236 solute carrier family 19, member 3 /FL=gb:AF271633.1 gb:NM_025243.1 NM_025243 solute carrier family 19 (thiamine transporter), member 3 SLC19A3 80704 NM_025243 /// XM_005246871 /// XM_005246874 /// XM_005246875 /// XM_006712779 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0015888 // thiamine transport // inferred from electronic annotation /// 0042723 // thiamine-containing compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071934 // thiamine transmembrane transport // inferred from electronic annotation /// 0071934 // thiamine transmembrane transport // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005542 // folic acid binding // inferred from electronic annotation /// 0008518 // reduced folate carrier activity // inferred from electronic annotation /// 0015403 // thiamine uptake transmembrane transporter activity // inferred from sequence or structural similarity 220737_at AF184965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF184965.1 /DEF=Homo sapiens ribosomal S6 kinase (RPS6KA6) mRNA, complete cds. /FEA=mRNA /GEN=RPS6KA6 /PROD=ribosomal S6 kinase /DB_XREF=gi:6467561 /UG=Hs.40434 ribosomal protein S6 kinase, 90kD, polypeptide 6 /FL=gb:AF184965.1 gb:NM_014496.1 AF184965 ribosomal protein S6 kinase, 90kDa, polypeptide 6 RPS6KA6 27330 NM_014496 /// XM_005262123 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045992 // negative regulation of embryonic development // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 2000381 // negative regulation of mesoderm development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220738_s_at NM_014496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014496.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 90kD, polypeptide 6 (RPS6KA6), mRNA. /FEA=mRNA /GEN=RPS6KA6 /PROD=ribosomal protein S6 kinase, 90kD, polypeptide6 /DB_XREF=gi:7657525 /UG=Hs.40434 ribosomal protein S6 kinase, 90kD, polypeptide 6 /FL=gb:AF184965.1 gb:NM_014496.1 NM_014496 ribosomal protein S6 kinase, 90kDa, polypeptide 6 RPS6KA6 27330 NM_014496 /// XM_005262123 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045992 // negative regulation of embryonic development // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 2000381 // negative regulation of mesoderm development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220739_s_at NM_017623 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017623.1 /DEF=Homo sapiens hypothetical protein FLJ20018 (FLJ20018), mRNA. /FEA=mRNA /GEN=FLJ20018 /PROD=hypothetical protein FLJ20018 /DB_XREF=gi:8923022 /UG=Hs.44095 hypothetical protein FLJ20018 /FL=gb:NM_017623.1 NM_017623 cyclin M3 CNNM3 26505 NM_017623 /// NM_199078 /// XM_005263917 /// XM_005263918 /// XM_006712418 /// XR_244887 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 220740_s_at NM_005135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005135.1 /DEF=Homo sapiens solute carrier family 12 (potassiumchloride transporters), member 6 (SLC12A6), mRNA. /FEA=mRNA /GEN=SLC12A6 /PROD=solute carrier family 12 (potassiumchloridetransporters), member 6 /DB_XREF=gi:4826779 /UG=Hs.4876 solute carrier family 12 (potassiumchloride transporters), member 6 /FL=gb:AF108831.1 gb:NM_005135.1 NM_005135 solute carrier family 12 (potassium/chloride transporter), member 6 SLC12A6 9990 NM_001042494 /// NM_001042495 /// NM_001042496 /// NM_001042497 /// NM_005135 /// NM_133647 /// XM_006720793 /// XR_429476 0001525 // angiogenesis // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from direct assay /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from direct assay /// 0010107 // potassium ion import // inferred from direct assay /// 0035826 // rubidium ion transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071476 // cellular hypotonic response // inferred from mutant phenotype /// 0071477 // cellular hypotonic salinity response // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from electronic annotation /// 0015079 // potassium ion transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015377 // cation:chloride symporter activity // inferred from electronic annotation /// 0015379 // potassium:chloride symporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035827 // rubidium ion transmembrane transporter activity // inferred from mutant phenotype 220741_s_at NM_006903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006903.1 /DEF=Homo sapiens inorganic pyrophosphatase (SID6-306), mRNA. /FEA=mRNA /GEN=SID6-306 /PROD=inorganic pyrophosphatase /DB_XREF=gi:13491177 /UG=Hs.5123 inorganic pyrophosphatase /FL=gb:NM_006903.1 gb:AB026722.1 NM_006903 pyrophosphatase (inorganic) 2 PPA2 27068 NM_001034191 /// NM_001034192 /// NM_001034193 /// NM_006903 /// NM_176866 /// NM_176867 /// NM_176869 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0071344 // diphosphate metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004427 // inorganic diphosphatase activity // traceable author statement /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220742_s_at NM_018297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018297.1 /DEF=Homo sapiens hypothetical protein FLJ11005 (FLJ11005), mRNA. /FEA=mRNA /GEN=FLJ11005 /PROD=hypothetical protein FLJ11005 /DB_XREF=gi:8922817 /UG=Hs.63657 hypothetical protein FLJ11005 /FL=gb:NM_018297.1 NM_018297 N-glycanase 1 NGLY1 55768 NM_001145293 /// NM_001145294 /// NM_001145295 /// NM_018297 /// NM_025105 /// XM_005265316 /// XM_005265317 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000224 // peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220743_at NM_014117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014117.1 /DEF=Homo sapiens PRO0149 protein (PRO0149), mRNA. /FEA=mRNA /GEN=PRO0149 /PROD=PRO0149 protein /DB_XREF=gi:7662527 /UG=Hs.64056 PRO0149 protein /FL=gb:AF090898.1 gb:NM_014117.1 NM_014117 220744_s_at NM_018262 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018262.1 /DEF=Homo sapiens hypothetical protein FLJ10897 (FLJ10897), mRNA. /FEA=mRNA /GEN=FLJ10897 /PROD=hypothetical protein FLJ10897 /DB_XREF=gi:8922747 /UG=Hs.70202 WD repeat domain 10 /FL=gb:NM_018262.1 NM_018262 intraflagellar transport 122 homolog (Chlamydomonas) /// intraflagellar transport protein 122 homolog IFT122 /// LOC101927266 55764 /// 101927266 NM_001280541 /// NM_001280545 /// NM_001280546 /// NM_018262 /// NM_052985 /// NM_052989 /// NM_052990 /// XM_005247603 /// XM_005247604 /// XM_005247607 /// XM_005247608 /// XM_005247609 /// XM_005247610 /// XM_005247611 /// XM_005247924 /// XM_005275951 /// XM_005276237 /// XM_006713689 /// XM_006713690 /// XM_006713691 /// XM_006713692 /// XM_006713693 /// XM_006713694 /// XM_006713695 /// XR_241563 /// XR_249546 /// XR_251444 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from sequence or structural similarity /// 0035721 // intraciliary retrograde transport // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0060173 // limb development // inferred from sequence or structural similarity /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061512 // protein localization to cilium // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 220745_at NM_013371 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013371.1 /DEF=Homo sapiens interleukin 19 (IL19), mRNA. /FEA=mRNA /GEN=IL19 /PROD=interleukin 19 /DB_XREF=gi:7019574 /UG=Hs.71979 interleukin 19 /FL=gb:AF192498.1 gb:NM_013371.1 NM_013371 interleukin 19 IL19 29949 NM_013371 /// NM_153758 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0042226 // interleukin-6 biosynthetic process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // traceable author statement 220746_s_at NM_016290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016290.1 /DEF=Homo sapiens retinoid x receptor interacting protein (LOC51720), mRNA. /FEA=mRNA /GEN=LOC51720 /PROD=retinoid x receptor interacting protein /DB_XREF=gi:7706482 /UG=Hs.7889 retinoid x receptor interacting protein /FL=gb:AF113538.1 gb:NM_016290.1 NM_016290 ubiquitin interaction motif containing 1 UIMC1 51720 NM_001199297 /// NM_001199298 /// NM_016290 /// XM_005265930 /// XM_005265931 /// XM_005265932 /// XM_005265933 /// XM_005265934 /// XM_005265935 /// XM_005265936 /// XM_006714871 /// XM_006714872 /// XM_006714873 /// XM_006714874 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0070537 // histone H2A K63-linked deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from direct assay 220747_at NM_014162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014162.1 /DEF=Homo sapiens HSPC072 protein (HSPC072), mRNA. /FEA=mRNA /GEN=HSPC072 /PROD=HSPC072 protein /DB_XREF=gi:7661779 /UG=Hs.87329 HSPC072 protein /FL=gb:AF161557.1 gb:NM_014162.1 NM_014162 long intergenic non-protein coding RNA 652 LINC00652 29075 NM_014162 /// NR_026883 /// NR_026884 220748_s_at NM_016202 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016202.1 /DEF=Homo sapiens LDL induced EC protein (LOC51157), mRNA. /FEA=mRNA /GEN=LOC51157 /PROD=LDL induced EC protein /DB_XREF=gi:7705880 /UG=Hs.94392 LDL induced EC protein /FL=gb:AF184939.1 gb:NM_016202.1 NM_016202 zinc finger protein 580 ZNF580 51157 NM_001163423 /// NM_016202 /// NM_207115 /// XM_005258967 /// XM_005258968 /// XM_006723236 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 220749_at NM_024688 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024688.1 /DEF=Homo sapiens hypothetical protein FLJ13031 (FLJ13031), mRNA. /FEA=mRNA /GEN=FLJ13031 /PROD=hypothetical protein FLJ13031 /DB_XREF=gi:13375961 /UG=Hs.97757 hypothetical protein FLJ13031 /FL=gb:NM_024688.1 NM_024688 coiled-coil domain containing 7 CCDC7 79741 NM_001026383 /// NM_024688 /// NM_145023 /// NR_109826 /// NR_109827 /// XM_005252593 /// XM_005252595 /// XM_006717504 /// XM_006717505 /// XM_006717506 220750_s_at NM_022356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022356.1 /DEF=Homo sapiens growth suppressor 1 (GROS1), mRNA. /FEA=mRNA /GEN=GROS1 /PROD=growth suppressor 1 /DB_XREF=gi:11641270 /UG=Hs.10114 growth suppressor 1 /FL=gb:AF097431.1 gb:NM_022356.1 NM_022356 leucine proline-enriched proteoglycan (leprecan) 1 LEPRE1 64175 NM_001146289 /// NM_001243246 /// NM_022356 /// XM_005271110 0006457 // protein folding // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0016049 // cell growth // inferred from electronic annotation /// 0018126 // protein hydroxylation // inferred from mutant phenotype /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from sequence or structural similarity /// 0050708 // regulation of protein secretion // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060348 // bone development // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity /// 1901874 // negative regulation of post-translational protein modification // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032991 // macromolecular complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0019797 // procollagen-proline 3-dioxygenase activity // inferred from sequence or structural similarity /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 220751_s_at NM_016348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016348.1 /DEF=Homo sapiens chromosome 5 open reading frame 4 (C5ORF4), mRNA. /FEA=mRNA /GEN=C5ORF4 /PROD=putative tumor suppressor /DB_XREF=gi:7705942 /UG=Hs.10235 chromosome 5 open reading frame 4 /FL=gb:AF159165.1 gb:NM_016348.1 NM_016348 fatty acid hydroxylase domain containing 2 FAXDC2 10826 NM_016348 /// NM_032385 /// XM_005268356 /// XM_005268358 /// XM_006714753 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 220752_at NM_016158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016158.1 /DEF=Homo sapiens erythrocyte transmembrane protein (LOC51145), mRNA. /FEA=mRNA /GEN=LOC51145 /PROD=erythrocyte transmembrane protein /DB_XREF=gi:7705856 /UG=Hs.104671 erythrocyte transmembrane protein /FL=gb:AF159054.1 gb:NM_016158.1 NM_016158 uncharacterized LOC51145 LOC51145 51145 NM_016158 /// NR_122032 /// XR_108997 /// XR_171809 0016021 // integral component of membrane // inferred from electronic annotation 220753_s_at NM_015974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015974.1 /DEF=Homo sapiens lambda-crystallin (LOC51084), mRNA. /FEA=mRNA /GEN=LOC51084 /PROD=lambda-crystallin /DB_XREF=gi:7705743 /UG=Hs.108896 lambda-crystallin /FL=gb:AF077049.1 gb:NM_015974.1 NM_015974 crystallin, lambda 1 CRYL1 51084 NM_015974 /// XM_005266415 /// XM_005266416 /// XR_245386 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050104 // L-gulonate 3-dehydrogenase activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 220754_at NM_024720 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024720.1 /DEF=Homo sapiens hypothetical protein FLJ23510 (FLJ23510), mRNA. /FEA=mRNA /GEN=FLJ23510 /PROD=hypothetical protein FLJ23510 /DB_XREF=gi:13376024 /UG=Hs.109005 hypothetical protein FLJ23510 /FL=gb:NM_024720.1 NM_024720 armadillo repeat containing 9 ARMC9 80210 NM_001271466 /// NM_001291656 /// NM_025139 0070062 // extracellular vesicular exosome // inferred from direct assay 220755_s_at NM_016947 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016947.1 /DEF=Homo sapiens G8 protein (G8), mRNA. /FEA=mRNA /GEN=G8 /PROD=G8 protein /DB_XREF=gi:8393383 /UG=Hs.109798 G8 protein /FL=gb:NM_016947.1 NM_016947 chromosome 6 open reading frame 48 C6orf48 50854 NM_001040437 /// NM_001040438 /// NM_001287482 /// NM_001287483 /// NM_001287484 /// NM_001287485 /// NM_001287486 /// NM_001287487 /// NM_001287488 /// NM_016947 220756_s_at NM_017986 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017986.1 /DEF=Homo sapiens hypothetical protein FLJ10060 (FLJ10060), mRNA. /FEA=mRNA /GEN=FLJ10060 /PROD=hypothetical protein FLJ10060 /DB_XREF=gi:8922213 /UG=Hs.110128 hypothetical protein FLJ10060 /FL=gb:NM_017986.1 NM_017986 solute carrier family 52 (riboflavin transporter), member 1 SLC52A1 55065 NM_001104577 /// NM_017986 /// XM_005256709 0006810 // transport // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0032218 // riboflavin transport // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0032217 // riboflavin transporter activity // inferred from direct assay 220757_s_at NM_025241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025241.1 /DEF=Homo sapiens UBX domain-containing gene 1 (UBXD1), mRNA. /FEA=mRNA /GEN=UBXD1 /PROD=UBX domain-containing gene 1 /DB_XREF=gi:13376853 /UG=Hs.11081 UBX domain-containing 2 /FL=gb:AF272893.1 gb:NM_025241.1 NM_025241 microRNA 4746 /// UBX domain protein 6 MIR4746 /// UBXN6 80700 /// 100616371 NM_001171091 /// NM_025241 /// NR_039901 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220758_s_at NM_019055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019055.1 /DEF=Homo sapiens hypothetical protein (FLJ20798), mRNA. /FEA=mRNA /GEN=FLJ20798 /PROD=hypothetical protein /DB_XREF=gi:9506698 /UG=Hs.111518 hypothetical protein /FL=gb:NM_019055.1 NM_019055 roundabout, axon guidance receptor, homolog 4 (Drosophila) ROBO4 54538 NM_019055 /// XM_005271596 /// XM_005271597 /// XM_006718861 0001525 // angiogenesis // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030334 // regulation of cell migration // non-traceable author statement /// 0030336 // negative regulation of cell migration // inferred from electronic annotation 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220759_at NM_022360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022360.1 /DEF=Homo sapiens human epididymis-specific 3 beta (HE3-BETA), mRNA. /FEA=mRNA /GEN=HE3-BETA /PROD=human epididymis-specific 3 beta /DB_XREF=gi:11641278 /UG=Hs.112952 human epididymis-specific 3 beta /FL=gb:NM_022360.1 NM_022360 epididymal protein 3B EDDM3B 64184 NM_022360 0007286 // spermatid development // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 220760_x_at NM_024733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024733.1 /DEF=Homo sapiens hypothetical protein FLJ14345 (FLJ14345), mRNA. /FEA=mRNA /GEN=FLJ14345 /PROD=hypothetical protein FLJ14345 /DB_XREF=gi:13376051 /UG=Hs.117270 hypothetical protein FLJ14345 /FL=gb:NM_024733.1 NM_024733 zinc finger protein 665 ZNF665 79788 NM_024733 /// XM_005259266 /// XM_006723387 /// XM_006723388 /// XM_006723389 /// XM_006723390 /// XM_006723391 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220761_s_at NM_016281 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016281.1 /DEF=Homo sapiens STE20-like kinase (JIK), mRNA. /FEA=mRNA /GEN=JIK /PROD=STE20-like kinase /DB_XREF=gi:7705559 /UG=Hs.12040 STE20-like kinase /FL=gb:AF179867.1 gb:NM_016281.1 NM_016281 TAO kinase 3 TAOK3 51347 NM_016281 /// XM_005253897 /// XM_005253898 /// XM_006719445 /// XM_006719446 0000165 // MAPK cascade // inferred from mutant phenotype /// 0000186 // activation of MAPKK activity // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from direct assay /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220762_s_at NM_022446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022446.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1-like (GNB1L), mRNA. /FEA=mRNA /GEN=GNB1L /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 1-like /DB_XREF=gi:13430857 /UG=Hs.120565 guanine nucleotide binding protein (G protein), beta polypeptide 1-like /FL=gb:AF238328.1 gb:NM_022446.1 NM_022446 guanine nucleotide binding protein (G protein), beta polypeptide 1-like GNB1L 54584 NM_053004 0006915 // apoptotic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0035176 // social behavior // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 220763_at NM_025015 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025015.1 /DEF=Homo sapiens KIAA0417 gene product (KIAA0417), mRNA. /FEA=mRNA /GEN=KIAA0417 /PROD=hypothetical protein FLJ13874 /DB_XREF=gi:13435150 /UG=Hs.12385 KIAA0417 gene product /FL=gb:NM_025015.1 NM_025015 heat shock 70kDa protein 12A HSPA12A 259217 NM_025015 /// XM_005269672 /// XM_005269673 /// XM_006717746 /// XM_006717747 0006950 // response to stress // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 220764_at NM_019853 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019853.1 /DEF=Homo sapiens protein phosphatase 4 regulatory subunit 2 (PPP4R2), mRNA. /FEA=mRNA /GEN=PPP4R2 /PROD=protein phosphatase 4 regulatory subunit 2 /DB_XREF=gi:9790172 /UG=Hs.125682 protein phosphatase 4 regulatory subunit 2 /FL=gb:NM_019853.1 NM_019853 protein phosphatase 4, regulatory subunit 2 PPP4R2 151987 NM_174907 0006397 // mRNA processing // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030289 // protein phosphatase 4 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030362 // protein phosphatase type 4 regulator activity // inferred from mutant phenotype /// 0030674 // protein binding, bridging // inferred from mutant phenotype 220765_s_at NM_017980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017980.1 /DEF=Homo sapiens hypothetical protein FLJ10044 (FLJ10044), mRNA. /FEA=mRNA /GEN=FLJ10044 /PROD=hypothetical protein FLJ10044 /DB_XREF=gi:8922203 /UG=Hs.127273 hypothetical protein FLJ10044 /FL=gb:NM_017980.1 NM_017980 LIM and senescent cell antigen-like domains 2 LIMS2 55679 NM_001136037 /// NM_001161403 /// NM_001161404 /// NM_001256542 /// NM_017980 /// XM_005263709 /// XM_005263710 /// XM_006712627 /// XM_006712628 /// XR_427100 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220766_at NM_017589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017589.1 /DEF=Homo sapiens B-cell translocation gene 4 (BTG4), mRNA. /FEA=mRNA /GEN=BTG4 /PROD=B-cell translocation gene 4 /DB_XREF=gi:8923957 /UG=Hs.128180 B-cell translocation gene 4 /FL=gb:NM_017589.1 NM_017589 B-cell translocation gene 4 BTG4 54766 NM_017589 /// XM_005271601 /// XM_005271602 /// XM_006718862 /// XM_006718863 /// XM_006718864 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030182 // neuron differentiation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation 220767_at NM_018619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018619.1 /DEF=Homo sapiens hypothetical protein PRO2133 (PRO2133), mRNA. /FEA=mRNA /GEN=PRO2133 /PROD=hypothetical protein PRO2133 /DB_XREF=gi:8924121 /UG=Hs.128564 hypothetical protein PRO2133 /FL=gb:AF116688.1 gb:NM_018619.1 NM_018619 220768_s_at NM_004384 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004384.1 /DEF=Homo sapiens casein kinase 1, gamma 3 (CSNK1G3), mRNA. /FEA=mRNA /GEN=CSNK1G3 /PROD=casein kinase 1, gamma 3 /DB_XREF=gi:4758079 /UG=Hs.129206 casein kinase 1, gamma 3 /FL=gb:AF049089.1 gb:NM_004384.1 NM_004384 casein kinase 1, gamma 3 CSNK1G3 1456 NM_001031812 /// NM_001044722 /// NM_001044723 /// NM_001270572 /// NM_001270573 /// NM_001270574 /// NM_004384 /// XM_005271891 /// XM_005271892 /// XM_005271893 /// XM_005271894 /// XM_005271895 /// XM_005271896 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220769_s_at NM_024763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024763.1 /DEF=Homo sapiens hypothetical protein FLJ23129 (FLJ23129), mRNA. /FEA=mRNA /GEN=FLJ23129 /PROD=hypothetical protein FLJ23129 /DB_XREF=gi:13376102 /UG=Hs.130401 hypothetical protein FLJ23129 /FL=gb:NM_024763.1 NM_024763 WD repeat domain 78 WDR78 79819 NM_024763 /// NM_207014 /// XM_005271212 /// XM_005271213 0005515 // protein binding // inferred from electronic annotation 220770_s_at NM_022090 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022090.1 /DEF=Homo sapiens transposon-derived Buster3 transposase-like (LOC63920), mRNA. /FEA=mRNA /GEN=LOC63920 /PROD=transposon-derived Buster3 transposase-like /DB_XREF=gi:11545804 /UG=Hs.131250 transposon-derived Buster3 transposase-like /FL=gb:NM_022090.1 NM_022090 zinc finger, BED-type containing 8 ZBED8 63920 NM_022090 /// XM_005265958 0005739 // mitochondrion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 220771_at NM_016181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016181.1 /DEF=Homo sapiens melanoma antigen (LOC51152), mRNA. /FEA=mRNA /GEN=LOC51152 /PROD=melanoma antigen /DB_XREF=gi:7705870 /UG=Hs.132526 melanoma antigen /FL=gb:AF172850.1 gb:NM_016181.1 NM_016181 long intergenic non-protein coding RNA 328 LINC00328 51152 NM_016181 /// XR_041657 220772_at NM_021812 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021812.1 /DEF=Homo sapiens blepharophimosis, epicanthus inversus and ptosis, candidate 1 (BPESC1), mRNA. /FEA=mRNA /GEN=BPESC1 /PROD=blepharophimosis, epicanthus inversus andptosis, candidate 1 /DB_XREF=gi:11141882 /UG=Hs.132622 blepharophimosis, epicanthus inversus and ptosis, candidate 1 /FL=gb:AF196865.1 gb:NM_021812.1 NM_021812 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding) BPESC1 60467 NM_021812 /// NR_026783 220773_s_at NM_020806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020806.1 /DEF=Homo sapiens gephyrin (GPH), mRNA. /FEA=mRNA /GEN=GPH /PROD=gephryin /DB_XREF=gi:10880982 /UG=Hs.13405 gephyrin /FL=gb:NM_020806.1 NM_020806 gephyrin GPHN 10243 NM_001024218 /// NM_020806 /// XM_005267250 /// XM_005267253 /// XM_005267254 /// XM_006720003 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006777 // Mo-molybdopterin cofactor biosynthetic process // inferred from electronic annotation /// 0007529 // establishment of synaptic specificity at neuromuscular junction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032324 // molybdopterin cofactor biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061598 // molybdopterin adenylyltransferase activity // inferred from electronic annotation /// 0061599 // molybdopterin molybdotransferase activity // inferred from electronic annotation 220774_at NM_017653 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017653.1 /DEF=Homo sapiens hypothetical protein FLJ20071 (FLJ20071), mRNA. /FEA=mRNA /GEN=FLJ20071 /PROD=hypothetical protein FLJ20071 /DB_XREF=gi:8923078 /UG=Hs.14328 hypothetical protein FLJ20071 /FL=gb:NM_017653.1 NM_017653 dymeclin DYM 54808 NM_017653 /// XM_006722485 /// XM_006722486 /// XM_006722487 /// XM_006722488 /// XM_006722489 /// XM_006722490 /// XM_006722491 /// XM_006722492 0007030 // Golgi organization // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 220775_s_at NM_018314 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018314.1 /DEF=Homo sapiens hypothetical protein FLJ11068 (FLJ11068), mRNA. /FEA=mRNA /GEN=FLJ11068 /PROD=hypothetical protein FLJ11068 /DB_XREF=gi:8922849 /UG=Hs.143607 hypothetical protein FLJ11068 /FL=gb:NM_018314.1 NM_018314 UEV and lactate/malate dehyrogenase domains UEVLD 55293 NM_001040697 /// NM_001040698 /// NM_001261382 /// NM_001261383 /// NM_001261384 /// NM_001261385 /// NM_001261386 /// NM_018314 /// XM_005253001 /// XM_006718255 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 220776_at NM_013348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013348.1 /DEF=Homo sapiens potassium inwardly-rectifying channel,subfamily J, member 14 (KCNJ14), mRNA. /FEA=mRNA /GEN=KCNJ14 /PROD=potassium inwardly-rectifying channel,subfamilyJ, member 14 /DB_XREF=gi:7019438 /UG=Hs.144011 potassium inwardly-rectifying channel,subfamily J, member 14 /FL=gb:AF081466.1 gb:NM_013348.1 NM_013348 potassium inwardly-rectifying channel, subfamily J, member 14 KCNJ14 3770 NM_013348 /// NM_170720 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation 220777_at NM_022113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022113.1 /DEF=Homo sapiens kinesin family member 13A (KIF13A), mRNA. /FEA=mRNA /GEN=KIF13A /PROD=kinesin family member 13A /DB_XREF=gi:11545828 /UG=Hs.146286 kinesin family member 13A /FL=gb:NM_022113.1 NM_022113 kinesin family member 13A KIF13A 63971 NM_001105566 /// NM_001105567 /// NM_001105568 /// NM_001243423 /// NM_022113 /// XM_005249289 /// XM_005249290 /// XM_005249291 /// XM_005249292 /// XM_005249293 /// XM_005249294 /// XM_006715166 /// XM_006715167 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008333 // endosome to lysosome transport // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0072383 // plus-end-directed vesicle transport along microtubule // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032588 // trans-Golgi network membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 220778_x_at NM_020241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020241.1 /DEF=Homo sapiens semaphorin Rs, short form (LOC56991), mRNA. /FEA=mRNA /GEN=LOC56991 /PROD=semaphorin Rs, short form /DB_XREF=gi:9910379 /UG=Hs.148932 semaphorin Rs, short form /FL=gb:AF216389.1 gb:NM_020241.1 NM_020241 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B SEMA6B 10501 NM_020241 /// NM_032108 /// NM_133327 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 220779_at NM_016233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016233.1 /DEF=Homo sapiens peptidylarginine deiminase type III (LOC51702), mRNA. /FEA=mRNA /GEN=LOC51702 /PROD=peptidylarginine deiminase type III /DB_XREF=gi:7706446 /UG=Hs.149195 peptidylarginine deiminase type III /FL=gb:AB026831.1 gb:NM_016233.1 NM_016233 peptidyl arginine deiminase, type III PADI3 51702 NM_016233 /// XM_006710684 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018101 // protein citrullination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004668 // protein-arginine deiminase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220780_at NM_015715 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015715.1 /DEF=Homo sapiens group III secreted phospholipase A2 (GIII-SPLA2), mRNA. /FEA=mRNA /GEN=GIII-SPLA2 /PROD=group III secreted phospholipase A2 /DB_XREF=gi:7657125 /UG=Hs.149623 group III secreted phospholipase A2 /FL=gb:AF220490.1 gb:NM_015715.1 NM_015715 phospholipase A2, group III PLA2G3 50487 NM_015715 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // traceable author statement 220781_at NM_017418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017418.1 /DEF=Homo sapiens deleted in esophageal cancer 1 (DEC1), mRNA. /FEA=mRNA /GEN=DEC1 /PROD=deleted in esophageal cancer 1 /DB_XREF=gi:8393249 /UG=Hs.158035 deleted in esophageal cancer 1 /FL=gb:AB022761.1 gb:NM_017418.1 NM_017418 deleted in esophageal cancer 1 DEC1 50514 NM_017418 0008285 // negative regulation of cell proliferation // traceable author statement 220782_x_at NM_019598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019598.1 /DEF=Homo sapiens kallikrein 12 (KLK12), mRNA. /FEA=mRNA /GEN=KLK12 /PROD=kallikrein 12 /DB_XREF=gi:9665235 /UG=Hs.159679 kallikrein 12 /FL=gb:NM_019598.1 NM_019598 kallikrein-related peptidase 12 KLK12 43849 NM_019598 /// NM_145894 /// NM_145895 /// XM_005258950 /// XM_005258951 0006508 // proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 220783_at NM_022122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022122.1 /DEF=Homo sapiens matrix metalloprotease 27 (MMP27), mRNA. /FEA=mRNA /GEN=MMP27 /PROD=matrix metalloprotease 27 /DB_XREF=gi:11545844 /UG=Hs.161839 matrix metalloprotease 27 /FL=gb:AF195192.1 gb:NM_022122.1 NM_022122 matrix metallopeptidase 27 MMP27 64066 NM_022122 0006508 // proteolysis // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220784_s_at NM_021995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021995.1 /DEF=Homo sapiens urotensin 2 (UTS2), transcript variant 1, mRNA. /FEA=mRNA /GEN=UTS2 /PROD=urotensin 2, preproprotein isoform a /DB_XREF=gi:12056478 /UG=Hs.162200 urotensin 2 /FL=gb:NM_021995.1 gb:AF140630.1 NM_021995 urotensin 2 UTS2 10911 NM_006786 /// NM_021995 0001666 // response to hypoxia // inferred from electronic annotation /// 0003105 // negative regulation of glomerular filtration // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0010841 // positive regulation of circadian sleep/wake cycle, wakefulness // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046005 // positive regulation of circadian sleep/wake cycle, REM sleep // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 220785_at NM_021995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021995.1 /DEF=Homo sapiens urotensin 2 (UTS2), transcript variant 1, mRNA. /FEA=mRNA /GEN=UTS2 /PROD=urotensin 2, preproprotein isoform a /DB_XREF=gi:12056478 /UG=Hs.162200 urotensin 2 /FL=gb:NM_021995.1 gb:AF140630.1 NM_021995 urotensin 2 UTS2 10911 NM_006786 /// NM_021995 0001666 // response to hypoxia // inferred from electronic annotation /// 0003105 // negative regulation of glomerular filtration // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0010459 // negative regulation of heart rate // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0010763 // positive regulation of fibroblast migration // inferred from electronic annotation /// 0010841 // positive regulation of circadian sleep/wake cycle, wakefulness // inferred from electronic annotation /// 0032224 // positive regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035811 // negative regulation of urine volume // inferred from electronic annotation /// 0035814 // negative regulation of renal sodium excretion // inferred from electronic annotation /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046005 // positive regulation of circadian sleep/wake cycle, REM sleep // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation 220786_s_at NM_018018 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018018.1 /DEF=Homo sapiens hypothetical protein FLJ10191 (FLJ10191), mRNA. /FEA=mRNA /GEN=FLJ10191 /PROD=hypothetical protein FLJ10191 /DB_XREF=gi:8922270 /UG=Hs.165655 hypothetical protein FLJ10191 /FL=gb:NM_018018.1 NM_018018 solute carrier family 38, member 4 SLC38A4 55089 NM_001143824 /// NM_018018 /// XM_005268997 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 220787_at NM_018629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018629.1 /DEF=Homo sapiens hypothetical protein PRO2533 (PRO2533), mRNA. /FEA=mRNA /GEN=PRO2533 /PROD=hypothetical protein PRO2533 /DB_XREF=gi:8924177 /UG=Hs.166715 hypothetical protein PRO2533 /FL=gb:AF116706.1 gb:NM_018629.1 NM_018629 220788_s_at NM_017999 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017999.1 /DEF=Homo sapiens hypothetical protein FLJ10111 (FLJ10111), mRNA. /FEA=mRNA /GEN=FLJ10111 /PROD=hypothetical protein FLJ10111 /DB_XREF=gi:8922234 /UG=Hs.16725 hypothetical protein FLJ10111 /FL=gb:NM_017999.1 NM_017999 interferon regulatory factor 9 /// ring finger protein 31 IRF9 /// RNF31 10379 /// 55072 NM_006084 /// NM_017999 0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0023035 // CD40 signaling pathway // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0097039 // protein linear polyubiquitination // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0071797 // LUBAC complex // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220789_s_at NM_004749 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004749.1 /DEF=Homo sapiens cell cycle progression 2 protein (CPR2), mRNA. /FEA=mRNA /GEN=CPR2 /PROD=cell cycle progression 2 protein /DB_XREF=gi:4758045 /UG=Hs.170980 cell cycle progression 2 protein /FL=gb:AF011792.1 gb:NM_004749.1 NM_004749 small nucleolar RNA, H/ACA box 5B /// transforming growth factor beta regulator 4 SNORA5B /// TBRG4 9238 /// 677795 NM_001261834 /// NM_004749 /// NM_030900 /// NM_199122 /// NR_002990 0000080 // mitotic G1 phase // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220790_s_at NM_023945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023945.1 /DEF=Homo sapiens testis-expressed transmembrane-4 protein (TETM4), mRNA. /FEA=mRNA /GEN=TETM4 /PROD=testis-expressed transmembrane-4 protein /DB_XREF=gi:12965204 /UG=Hs.178066 membrane-spanning 4-domains, subfamily A, member 5 /FL=gb:AB013103.1 gb:AF321127.1 gb:NM_023945.1 NM_023945 membrane-spanning 4-domains, subfamily A, member 5 MS4A5 64232 NM_023945 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220791_x_at NM_014139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014139.1 /DEF=Homo sapiens sodium channel, voltage-gated, type XII, alpha polypeptide (SCN12A), mRNA. /FEA=mRNA /GEN=SCN12A /PROD=sodium channel, voltage-gated, type XII, alphapolypeptide /DB_XREF=gi:7657541 /UG=Hs.186877 sodium channel, voltage-gated, type XII, alpha polypeptide /FL=gb:AF109737.1 gb:NM_014139.1 NM_014139 sodium channel, voltage-gated, type XI, alpha subunit SCN11A 11280 NM_001287223 /// NM_014139 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019228 // neuronal action potential // not recorded /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // not recorded /// 0042493 // response to drug // traceable author statement /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0001518 // voltage-gated sodium channel complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0044299 // C-fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005248 // voltage-gated sodium channel activity // not recorded /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220792_at NM_018699 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018699.1 /DEF=Homo sapiens PR domain containing 5 (PRDM5), mRNA. /FEA=mRNA /GEN=PRDM5 /PROD=PR domain containing 5 /DB_XREF=gi:8923963 /UG=Hs.192867 PR domain containing 5 /FL=gb:AF272897.1 gb:NM_018699.1 NM_018699 PR domain containing 5 PRDM5 11107 NM_018699 /// XM_005262706 /// XM_005262707 /// XM_005262708 /// XM_006714072 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051567 // histone H3-K9 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from direct assay 220793_at NM_018666 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018666.1 /DEF=Homo sapiens putative tumor antigen (SAGE), mRNA. /FEA=mRNA /GEN=SAGE /PROD=putative tumor antigen /DB_XREF=gi:8924241 /UG=Hs.195292 putative tumor antigen /FL=gb:NM_018666.1 NM_018666 sarcoma antigen 1 SAGE1 55511 NM_018666 /// XM_006724764 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 220794_at NM_022469 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022469.1 /DEF=Homo sapiens hypothetical protein FLJ21195 similar to protein related to DAC and cerberus (FLJ21195), mRNA. /FEA=mRNA /GEN=FLJ21195 /PROD=hypothetical protein FLJ21195 similar to proteinrelated to DAC and cerberus /DB_XREF=gi:11968016 /UG=Hs.207407 hypothetical protein FLJ21195 similar to protein related to DAC and cerberus /FL=gb:NM_022469.1 NM_022469 gremlin 2, DAN family BMP antagonist GREM2 64388 NM_022469 /// XM_005273226 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from sequence or structural similarity /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0060300 // regulation of cytokine activity // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from sequence or structural similarity 220795_s_at NM_020836 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020836.1 /DEF=Homo sapiens KIAA1446 protein (KIAA1446), mRNA. /FEA=mRNA /GEN=KIAA1446 /PROD=similar to rat brain-enriched guanylatekinase-associated protein /DB_XREF=gi:13124764 /UG=Hs.211751 KIAA1446 protein /FL=gb:BC002607.1 gb:NM_020836.1 NM_020836 brain-enriched guanylate kinase-associated BEGAIN 57596 NM_001159531 /// NM_020836 /// XM_005267919 /// XM_005267920 /// XM_005267921 /// XM_006720221 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 220796_x_at NM_024881 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024881.1 /DEF=Homo sapiens hypothetical protein FLJ14251 (FLJ14251), mRNA. /FEA=mRNA /GEN=FLJ14251 /PROD=hypothetical protein FLJ14251 /DB_XREF=gi:13376323 /UG=Hs.214178 hypothetical protein FLJ14251 /FL=gb:NM_024881.1 NM_024881 solute carrier family 35, member E1 SLC35E1 79939 NM_024881 0006810 // transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220797_at NM_024086 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024086.1 /DEF=Homo sapiens hypothetical protein MGC3329 (MGC3329), mRNA. /FEA=mRNA /GEN=MGC3329 /PROD=hypothetical protein MGC3329 /DB_XREF=gi:13129083 /UG=Hs.222306 hypothetical protein MGC3329 /FL=gb:BC001213.1 gb:NM_024086.1 NM_024086 uncharacterized LOC284009 /// methyltransferase like 16 LOC284009 /// METTL16 79066 /// 284009 NM_001025459 /// NM_024086 /// NR_028335 /// XM_005256801 /// XR_429822 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220798_x_at NM_024888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024888.1 /DEF=Homo sapiens hypothetical protein FLJ11535 (FLJ11535), mRNA. /FEA=mRNA /GEN=FLJ11535 /PROD=hypothetical protein FLJ11535 /DB_XREF=gi:13376338 /UG=Hs.225170 hypothetical protein FLJ11535 /FL=gb:AL136596.1 gb:NM_024888.1 NM_024888 lipid phosphate phosphatase-related protein type 3 LPPR3 79948 NM_001270366 /// NM_024888 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220799_at NM_004752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004752.1 /DEF=Homo sapiens glial cells missing (Drosophila) homolog b (GCMB), mRNA. /FEA=mRNA /GEN=GCMB /PROD=glial cells missing (Drosophila) homolog b /DB_XREF=gi:4758419 /UG=Hs.227098 glial cells missing (Drosophila) homolog b /FL=gb:AF079550.1 gb:AF091149.1 gb:NM_004752.1 NM_004752 glial cells missing homolog 2 (Drosophila) GCM2 9247 NM_004752 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0060017 // parathyroid gland development // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220800_s_at NM_014547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014547.1 /DEF=Homo sapiens tropomodulin 3 (ubiquitous) (TMOD3), mRNA. /FEA=mRNA /GEN=TMOD3 /PROD=tropomodulin 3 (ubiquitous) /DB_XREF=gi:7657648 /UG=Hs.22826 tropomodulin 3 (ubiquitous) /FL=gb:AF237631.1 gb:NM_014547.1 NM_014547 tropomodulin 3 (ubiquitous) TMOD3 29766 NM_014547 /// XM_006720479 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005865 // striated muscle thin filament // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 220801_s_at NM_016527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016527.1 /DEF=Homo sapiens hydroxyacid oxidase 2 (long chain) (HAO2), mRNA. /FEA=mRNA /GEN=HAO2 /PROD=hydroxyacid oxidase 2 /DB_XREF=gi:7705392 /UG=Hs.236545 hydroxyacid oxidase 2 (long chain) /FL=gb:AF231917.1 gb:NM_016527.1 NM_016527 hydroxyacid oxidase 2 (long chain) HAO2 51179 NM_001005783 /// NM_016527 /// XM_005270913 /// XM_005270914 /// XM_005270915 /// XM_005270916 /// XM_005270917 /// XM_005270918 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0018924 // mandelate metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003973 // (S)-2-hydroxy-acid oxidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0010181 // FMN binding // inferred from electronic annotation /// 0015930 // glutamate synthase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016638 // oxidoreductase activity, acting on the CH-NH2 group of donors // inferred from electronic annotation /// 0052852 // very-long-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation /// 0052853 // long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity // inferred from direct assay /// 0052854 // medium-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation 220802_at NM_012285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012285.1 /DEF=Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 4 (KCNH4), mRNA. /FEA=mRNA /GEN=KCNH4 /PROD=potassium voltage-gated channel, subfamily H(eag-related), member 4 /DB_XREF=gi:6912445 /UG=Hs.241386 potassium voltage-gated channel, subfamily H (eag-related), member 4 /FL=gb:AB022698.1 gb:NM_012285.1 NM_012285 potassium voltage-gated channel, subfamily H (eag-related), member 4 KCNH4 23415 NM_012285 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220803_at NM_017597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017597.1 /DEF=Homo sapiens hypothetical protein DKFZp761K1824 (DKFZp761K1824), mRNA. /FEA=mRNA /GEN=DKFZp761K1824 /PROD=hypothetical protein DKFZp761K1824 /DB_XREF=gi:8922174 /UG=Hs.244803 hypothetical protein DKFZp761K1824 /FL=gb:NM_017597.1 NM_017597 Homo sapiens mRNA; cDNA DKFZp761K1824 (from clone DKFZp761K1824). /// STAM binding protein-like 1 BC069782 /// STAMBPL1 57559 NM_020799 /// XM_006717928 /// XM_006717929 /// XM_006717930 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220804_s_at NM_005427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005427.1 /DEF=Homo sapiens tumor protein p73 (TP73), mRNA. /FEA=mRNA /GEN=TP73 /PROD=tumor protein p73 /DB_XREF=gi:4885644 /UG=Hs.247753 tumor protein p73 /FL=gb:NM_005427.1 NM_005427 tumor protein p73 TP73 7161 NM_001126240 /// NM_001126241 /// NM_001126242 /// NM_001204184 /// NM_001204185 /// NM_001204186 /// NM_001204187 /// NM_001204188 /// NM_001204189 /// NM_001204190 /// NM_001204191 /// NM_001204192 /// NM_005427 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // not recorded /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010332 // response to gamma radiation // not recorded /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // not recorded /// 0033326 // cerebrospinal fluid secretion // inferred from electronic annotation /// 0034644 // cellular response to UV // not recorded /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // not recorded /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // not recorded /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 1902167 // positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0000785 // chromatin // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003684 // damaged DNA binding // not recorded /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220805_at NM_022304 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022304.1 /DEF=Homo sapiens histamine receptor H2 (HRH2), mRNA. /FEA=mRNA /GEN=HRH2 /PROD=histamine receptor H2 /DB_XREF=gi:13435404 /UG=Hs.247885 histamine receptor H2 /FL=gb:NM_022304.1 NM_022304 histamine receptor H2 HRH2 3274 NM_001131055 /// NM_022304 /// XM_005265904 /// XM_005265905 /// XM_005265907 /// XM_006714864 /// XM_006714865 /// XR_245274 0001696 // gastric acid secretion // inferred from electronic annotation /// 0001697 // histamine-induced gastric acid secretion // inferred from electronic annotation /// 0001698 // gastrin-induced gastric acid secretion // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // inferred from electronic annotation 220806_x_at NM_016541 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016541.1 /DEF=Homo sapiens guanine nucleotide binding protein 13, gamma (GNG13), mRNA. /FEA=mRNA /GEN=GNG13 /PROD=guanine nucleotide binding protein 13, gamma /DB_XREF=gi:7706566 /UG=Hs.247888 guanine nucleotide binding protein 13, gamma /FL=gb:AB030207.1 gb:NM_016541.1 NM_016541 guanine nucleotide binding protein (G protein), gamma 13 GNG13 51764 NM_016541 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0031681 // G-protein beta-subunit binding // inferred from physical interaction 220807_at NM_005331 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005331.2 /DEF=Homo sapiens hemoglobin, theta 1 (HBQ1), mRNA. /FEA=mRNA /GEN=HBQ1 /PROD=hemoglobin, theta 1 /DB_XREF=gi:6633804 /UG=Hs.247921 hemoglobin, theta 1 /FL=gb:NM_005331.2 NM_005331 hemoglobin, theta 1 HBQ1 3049 NM_005331 0006810 // transport // inferred from electronic annotation /// 0015671 // oxygen transport // inferred from electronic annotation 0005833 // hemoglobin complex // inferred from electronic annotation 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220808_at NM_016585 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016585.1 /DEF=Homo sapiens testicular haploid expressed gene (THEG), mRNA. /FEA=mRNA /GEN=THEG /PROD=testicular haploid expressed gene /DB_XREF=gi:7706120 /UG=Hs.250002 testicular haploid expressed gene /FL=gb:AF268610.1 gb:AB033129.1 gb:NM_016585.1 NM_016585 theg spermatid protein THEG 51298 NM_016585 /// NM_199202 /// XM_005259569 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051131 // chaperone-mediated protein complex assembly // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220809_at NM_024912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024912.1 /DEF=Homo sapiens hypothetical protein FLJ14327 (FLJ14327), mRNA. /FEA=mRNA /GEN=FLJ14327 /PROD=hypothetical protein FLJ14327 /DB_XREF=gi:13376375 /UG=Hs.250854 hypothetical protein FLJ14327 /FL=gb:NM_024912.1 NM_024912 220810_at NM_004921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004921.1 /DEF=Homo sapiens chloride channel, calcium activated, family member 3 (CLCA3), mRNA. /FEA=mRNA /GEN=CLCA3 /PROD=calcium activated chloride channel 3 precursor /DB_XREF=gi:4757997 /UG=Hs.251378 chloride channel, calcium activated, family member 3 /FL=gb:AF043976.1 gb:NM_004921.1 NM_004921 chloride channel accessory 3, pseudogene CLCA3P 9629 NM_004921 /// NR_024604 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0034707 // chloride channel complex // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation 220811_at NM_006093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006093.2 /DEF=Homo sapiens proteoglycan 3 (PRG3), mRNA. /FEA=mRNA /GEN=PRG3 /PROD=proteoglycan 3 /DB_XREF=gi:10092602 /UG=Hs.251386 proteoglycan 3 /FL=gb:AF132209.2 gb:NM_006093.2 NM_006093 proteoglycan 3 PRG3 10394 NM_006093 0001694 // histamine biosynthetic process // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0042554 // superoxide anion generation // inferred from direct assay /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045575 // basophil activation // inferred from direct assay 0030246 // carbohydrate binding // inferred from electronic annotation 220812_s_at NM_007072 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007072.1 /DEF=Homo sapiens HERV-H LTR-associating 2 (HHLA2), mRNA. /FEA=mRNA /GEN=HHLA2 /PROD=HERV-H LTR-associating 2 /DB_XREF=gi:5901963 /UG=Hs.252351 HERV-H LTR-associating 2 /FL=gb:AF126162.1 gb:NM_007072.1 NM_007072 HERV-H LTR-associating 2 HHLA2 11148 NM_001282556 /// NM_001282557 /// NM_001282558 /// NM_001282559 /// NM_007072 /// XM_005247080 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220813_at NM_020377 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020377.1 /DEF=Homo sapiens cysteinyl leukotriene CysLT2 receptor; cDNA: PSEC0146 from clone PLACE1006979 (LOC57105), mRNA. /FEA=mRNA /GEN=LOC57105 /PROD=cysteinyl leukotriene CysLT2 receptor; cDNA:PSEC0146 from clone PLACE1006979 /DB_XREF=gi:9966850 /UG=Hs.253706 cysteinyl leukotriene CysLT2 receptor; cDNA: PSEC0146 from clone PLACE1006979 /FL=gb:AB038269.1 gb:NM_020377.1 NM_020377 cysteinyl leukotriene receptor 2 CYSLTR2 57105 NM_020377 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001631 // cysteinyl leukotriene receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 220814_at NM_017964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017964.1 /DEF=Homo sapiens hypothetical protein FLJ20837 (FLJ20837), mRNA. /FEA=mRNA /GEN=FLJ20837 /PROD=hypothetical protein FLJ20837 /DB_XREF=gi:8923690 /UG=Hs.257005 hypothetical protein FLJ20837 /FL=gb:NM_017964.1 NM_017964 0006812 // cation transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 220815_at NM_013266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013266.1 /DEF=Homo sapiens alpha-catenin-like protein (VR22), mRNA. /FEA=mRNA /GEN=VR22 /PROD=alpha-catenin-like protein /DB_XREF=gi:7019570 /UG=Hs.257051 alpha-catenin-like protein /FL=gb:AF091606.1 gb:NM_013266.1 NM_013266 catenin (cadherin-associated protein), alpha 3 CTNNA3 29119 NM_001127384 /// NM_001291133 /// NM_013266 /// XM_005269717 /// XM_006717805 /// XM_006717806 /// XM_006717807 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from physical interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0045296 // cadherin binding // traceable author statement 220816_at NM_012152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012152.1 /DEF=Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7 (EDG7), mRNA. /FEA=mRNA /GEN=EDG7 /PROD=endothelial cell differentiation gene 7 /DB_XREF=gi:6912347 /UG=Hs.258583 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7 /FL=gb:AF127138.1 gb:AF186380.1 gb:NM_012152.1 gb:AF236117.1 NM_012152 lysophosphatidic acid receptor 3 LPAR3 23566 NM_012152 /// XM_006710542 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0032060 // bleb assembly // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0048672 // positive regulation of collateral sprouting // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // traceable author statement /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 220817_at NM_016179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016179.1 /DEF=Homo sapiens transient receptor potential channel 4 (TRPC4), mRNA. /FEA=mRNA /GEN=TRPC4 /PROD=transient receptor potential 4 /DB_XREF=gi:7706746 /UG=Hs.262960 transient receptor potential channel 4 /FL=gb:AF175406.1 gb:NM_016179.1 NM_016179 transient receptor potential cation channel, subfamily C, member 4 TRPC4 7223 NM_001135955 /// NM_001135956 /// NM_001135957 /// NM_001135958 /// NM_003306 /// NM_016179 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from mutant phenotype /// 0045296 // cadherin binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from electronic annotation 220818_s_at NM_016179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016179.1 /DEF=Homo sapiens transient receptor potential channel 4 (TRPC4), mRNA. /FEA=mRNA /GEN=TRPC4 /PROD=transient receptor potential 4 /DB_XREF=gi:7706746 /UG=Hs.262960 transient receptor potential channel 4 /FL=gb:AF175406.1 gb:NM_016179.1 NM_016179 transient receptor potential cation channel, subfamily C, member 4 TRPC4 7223 NM_001135955 /// NM_001135956 /// NM_001135957 /// NM_001135958 /// NM_003306 /// NM_016179 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0014051 // gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070509 // calcium ion import // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from mutant phenotype /// 0045296 // cadherin binding // inferred from physical interaction /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from electronic annotation 220819_at NM_024919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024919.1 /DEF=Homo sapiens hypothetical protein FLJ22615 (FLJ22615), mRNA. /FEA=mRNA /GEN=FLJ22615 /PROD=hypothetical protein FLJ22615 /DB_XREF=gi:13376389 /UG=Hs.266746 hypothetical protein FLJ22615 /FL=gb:NM_024919.1 NM_024919 FERM domain containing 1 FRMD1 79981 NM_001122841 /// NM_024919 /// NR_110312 /// XM_006715567 0005856 // cytoskeleton // inferred from electronic annotation 220820_at NM_018539 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018539.1 /DEF=Homo sapiens hypothetical protein PRO2822 (PRO2822), mRNA. /FEA=mRNA /GEN=PRO2822 /PROD=hypothetical protein PRO2822 /DB_XREF=gi:8924203 /UG=Hs.272034 hypothetical protein PRO2822 /FL=gb:AF119900.1 gb:NM_018539.1 NM_018539 220821_at NM_001480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001480.2 /DEF=Homo sapiens galanin receptor 1 (GALR1), mRNA. /FEA=mRNA /GEN=GALR1 /PROD=galanin receptor 1 /DB_XREF=gi:6031165 /UG=Hs.272191 galanin receptor 1 /FL=gb:U53511.1 gb:L34339.1 gb:NM_001480.2 gb:U23854.1 NM_001480 galanin receptor 1 GALR1 2587 NM_001480 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0007586 // digestion // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051464 // positive regulation of cortisol secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004966 // galanin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from direct assay /// 0042923 // neuropeptide binding // inferred from electronic annotation 220822_at NM_017973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017973.1 /DEF=Homo sapiens hypothetical protein FLJ10034 (FLJ10034), mRNA. /FEA=mRNA /GEN=FLJ10034 /PROD=hypothetical protein FLJ10034 /DB_XREF=gi:8922191 /UG=Hs.272205 hypothetical protein FLJ10034 /FL=gb:NM_017973.1 NM_017973 220823_at NM_017624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017624.1 /DEF=Homo sapiens hypothetical protein FLJ20019 (FLJ20019), mRNA. /FEA=mRNA /GEN=FLJ20019 /PROD=hypothetical protein FLJ20019 /DB_XREF=gi:8923025 /UG=Hs.272219 hypothetical protein FLJ20019 /FL=gb:NM_017624.1 NM_017624 hCG1732469 LOC729164 729164 NM_001080856 /// XR_109936 /// XR_112370 /// XR_171318 220824_at NM_017674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017674.1 /DEF=Homo sapiens hypothetical protein FLJ20123 (FLJ20123), mRNA. /FEA=mRNA /GEN=FLJ20123 /PROD=hypothetical protein FLJ20123 /DB_XREF=gi:8923119 /UG=Hs.272232 hypothetical protein FLJ20123 /FL=gb:NM_017674.1 NM_017674 220825_s_at NM_018240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018240.1 /DEF=Homo sapiens hypothetical protein FLJ10845 (FLJ10845), mRNA. /FEA=mRNA /GEN=FLJ10845 /PROD=hypothetical protein FLJ10845 /DB_XREF=gi:8922704 /UG=Hs.272234 hypothetical protein FLJ10845 /FL=gb:NM_018240.1 NM_018240 kin of IRRE like (Drosophila) KIRREL 55243 NM_001286349 /// NM_018240 /// XM_005245305 /// XM_005245306 /// XM_006711430 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from physical interaction 220826_at NM_018277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018277.1 /DEF=Homo sapiens hypothetical protein FLJ10932 (FLJ10932), mRNA. /FEA=mRNA /GEN=FLJ10932 /PROD=hypothetical protein FLJ10932 /DB_XREF=gi:8922778 /UG=Hs.272236 hypothetical protein FLJ10932 /FL=gb:NM_018277.1 NM_018277 t-complex 10-like TCP10L 140290 NM_018277 /// NM_144659 0005634 // nucleus // inferred from electronic annotation 220827_at NM_018329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018329.1 /DEF=Homo sapiens hypothetical protein FLJ11117 (FLJ11117), mRNA. /FEA=mRNA /GEN=FLJ11117 /PROD=hypothetical protein FLJ11117 /DB_XREF=gi:8922878 /UG=Hs.272243 hypothetical protein FLJ11117 /FL=gb:NM_018329.1 NM_018329 220828_s_at NM_018382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018382.1 /DEF=Homo sapiens hypothetical protein FLJ11292 (FLJ11292), mRNA. /FEA=mRNA /GEN=FLJ11292 /PROD=hypothetical protein FLJ11292 /DB_XREF=gi:8922980 /UG=Hs.272246 hypothetical protein FLJ11292 /FL=gb:NM_018382.1 NM_018382 uncharacterized protein FLJ11292 FLJ11292 55338 NM_018382 220829_s_at NM_020981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020981.1 /DEF=Homo sapiens UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (B3GALT1), mRNA. /FEA=mRNA /GEN=B3GALT1 /PROD=UDP-Gal:betaGlcNAc beta1,3-galactosyltransferase, polypeptide 1 /DB_XREF=gi:10304986 /UG=Hs.272261 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 /FL=gb:NM_020981.1 gb:AF117222.1 NM_020981 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 B3GALT1 8708 NM_020981 /// XM_005246931 /// XM_006712819 0006486 // protein glycosylation // inferred from direct assay /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0030259 // lipid glycosylation // non-traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0008499 // UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220830_at NM_016247 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016247.1 /DEF=Homo sapiens interphotoreceptor matrix proteoglycan 200 (SPACRCAN), mRNA. /FEA=mRNA /GEN=SPACRCAN /PROD=interphotoreceptor matrix proteoglycan 200 /DB_XREF=gi:7706716 /UG=Hs.272380 interphotoreceptor matrix proteoglycan 200 /FL=gb:AF173155.1 gb:AF157624.1 gb:NM_016247.1 NM_016247 interphotoreceptor matrix proteoglycan 2 IMPG2 50939 NM_016247 0007601 // visual perception // traceable author statement 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation 220831_at NM_016591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016591.1 /DEF=Homo sapiens core 2 beta-1,6-N-acetylglucosaminyltransferase 3 (LOC51301), mRNA. /FEA=mRNA /GEN=LOC51301 /PROD=core 2 beta-1,6-N-acetylglucosaminyltransferase3 /DB_XREF=gi:7706126 /UG=Hs.272404 core 2 beta-1,6-N-acetylglucosaminyltransferase 3 /FL=gb:AF132035.1 gb:NM_016591.1 NM_016591 glucosaminyl (N-acetyl) transferase 4, core 2 GCNT4 51301 NM_016591 0002121 // inter-male aggressive behavior // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060993 // kidney morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003829 // beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008109 // N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity // traceable author statement /// 0008375 // acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220832_at NM_016610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016610.1 /DEF=Homo sapiens Toll-like receptor 8 (LOC51311), mRNA. /FEA=mRNA /GEN=LOC51311 /PROD=Toll-like receptor 8 /DB_XREF=gi:7706147 /UG=Hs.272410 Toll-like receptor 8 /FL=gb:AF246971.1 gb:NM_016610.1 gb:AF245703.1 NM_016610 toll-like receptor 8 TLR8 51311 NM_016610 /// NM_138636 /// XM_005274543 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0016064 // immunoglobulin mediated immune response // traceable author statement /// 0034158 // toll-like receptor 8 signaling pathway // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0045078 // positive regulation of interferon-gamma biosynthetic process // inferred from direct assay /// 0045087 // innate immune response // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045089 // positive regulation of innate immune response // inferred from direct assay /// 0045356 // positive regulation of interferon-alpha biosynthetic process // inferred from direct assay /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from direct assay /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from mutant phenotype /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0000139 // Golgi membrane // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0036020 // endolysosome membrane // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation 220833_at NM_016241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016241.1 /DEF=Homo sapiens endomucin-1 (LOC51169), mRNA. /FEA=mRNA /GEN=LOC51169 /PROD=endomucin-1 /DB_XREF=gi:7705902 /UG=Hs.272558 endomucin-1 /FL=gb:AB034694.1 gb:NM_016241.1 NM_016241 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // /// 0016021 // integral component of membrane // traceable author statement 0030246 // carbohydrate binding // inferred from sequence or structural similarity 220834_at NM_017716 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017716.1 /DEF=Homo sapiens hypothetical protein FLJ20217 (FLJ20217), mRNA. /FEA=mRNA /GEN=FLJ20217 /PROD=hypothetical protein FLJ20217 /DB_XREF=gi:8923205 /UG=Hs.272789 hypothetical protein FLJ20217 /FL=gb:NM_017716.1 NM_017716 membrane-spanning 4-domains, subfamily A, member 12 MS4A12 54860 NM_001164470 /// NM_017716 /// XM_006718591 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220835_s_at NM_017757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017757.1 /DEF=Homo sapiens hypothetical protein FLJ20307 (FLJ20307), mRNA. /FEA=mRNA /GEN=FLJ20307 /PROD=hypothetical protein FLJ20307 /DB_XREF=gi:8923288 /UG=Hs.272792 hypothetical protein FLJ20307 /FL=gb:NM_017757.1 NM_017757 zinc finger protein 407 ZNF407 55628 NM_001146189 /// NM_001146190 /// NM_017757 /// XM_005266726 /// XM_006722500 /// XM_006722501 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220836_at NM_017757 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017757.1 /DEF=Homo sapiens hypothetical protein FLJ20307 (FLJ20307), mRNA. /FEA=mRNA /GEN=FLJ20307 /PROD=hypothetical protein FLJ20307 /DB_XREF=gi:8923288 /UG=Hs.272792 hypothetical protein FLJ20307 /FL=gb:NM_017757.1 NM_017757 zinc finger protein 407 ZNF407 55628 NM_001146189 /// NM_001146190 /// NM_017757 /// XM_005266726 /// XM_006722500 /// XM_006722501 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220837_at NM_017808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017808.1 /DEF=Homo sapiens hypothetical protein FLJ20413 (FLJ20413), mRNA. /FEA=mRNA /GEN=FLJ20413 /PROD=hypothetical protein FLJ20413 /DB_XREF=gi:8923381 /UG=Hs.272798 hypothetical protein FLJ20413 /FL=gb:NM_017808.1 NM_017808 uncharacterized LOC100996325 LOC100996325 100996325 NR_103444 220838_at NM_017820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017820.1 /DEF=Homo sapiens hypothetical protein FLJ20433 (FLJ20433), mRNA. /FEA=mRNA /GEN=FLJ20433 /PROD=hypothetical protein FLJ20433 /DB_XREF=gi:8923406 /UG=Hs.272799 hypothetical protein FLJ20433 /FL=gb:NM_017820.1 NM_017820 exonuclease 3'-5' domain containing 3 EXD3 54932 NM_001286823 /// NM_017820 /// NR_104598 /// NR_104599 /// XM_005266093 /// XM_006717151 /// XM_006717152 /// XM_006717153 /// XM_006717154 /// XM_006717155 /// XM_006717156 /// XM_006717157 /// XM_006717158 /// XM_006717159 /// XM_006717160 /// XM_006717161 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220839_at NM_014168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014168.1 /DEF=Homo sapiens HSPC133 protein (HSPC133), mRNA. /FEA=mRNA /GEN=HSPC133 /PROD=HSPC133 protein /DB_XREF=gi:7661791 /UG=Hs.273063 HSPC133 protein /FL=gb:AF161482.1 gb:NM_014168.1 NM_014168 methyltransferase like 5 METTL5 29081 NM_001293186 /// NM_001293187 /// NM_014168 /// XM_005246478 /// XM_005246479 /// XM_006712458 0001510 // RNA methylation // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009452 // 7-methylguanosine RNA capping // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 220840_s_at NM_018186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018186.1 /DEF=Homo sapiens hypothetical protein FLJ10706 (FLJ10706), mRNA. /FEA=mRNA /GEN=FLJ10706 /PROD=hypothetical protein FLJ10706 /DB_XREF=gi:8922604 /UG=Hs.273193 hypothetical protein FLJ10706 /FL=gb:NM_018186.1 NM_018186 chromosome 1 open reading frame 112 C1orf112 55732 NM_018186 /// XM_005245317 /// XM_005245319 220841_s_at NM_017651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017651.1 /DEF=Homo sapiens hypothetical protein FLJ20069 (FLJ20069), mRNA. /FEA=mRNA /GEN=FLJ20069 /PROD=hypothetical protein FLJ20069 /DB_XREF=gi:8923074 /UG=Hs.273294 hypothetical protein FLJ20069 /FL=gb:NM_017651.1 NM_017651 Abelson helper integration site 1 AHI1 54806 NM_001134830 /// NM_001134831 /// NM_001134832 /// NM_017651 /// XM_005267039 /// XM_006715507 /// XR_427973 0001738 // morphogenesis of a polarized epithelium // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0006903 // vesicle targeting // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030862 // positive regulation of polarized epithelial cell differentiation // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035844 // cloaca development // inferred from sequence or structural similarity /// 0035845 // photoreceptor cell outer segment organization // inferred from sequence or structural similarity /// 0039008 // pronephric nephron tubule morphogenesis // inferred from sequence or structural similarity /// 0039023 // pronephric duct morphogenesis // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0065001 // specification of axis polarity // inferred from sequence or structural similarity /// 0070121 // Kupffer's vesicle development // inferred from sequence or structural similarity /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071599 // otic vesicle development // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220842_at NM_017651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017651.1 /DEF=Homo sapiens hypothetical protein FLJ20069 (FLJ20069), mRNA. /FEA=mRNA /GEN=FLJ20069 /PROD=hypothetical protein FLJ20069 /DB_XREF=gi:8923074 /UG=Hs.273294 hypothetical protein FLJ20069 /FL=gb:NM_017651.1 NM_017651 Abelson helper integration site 1 AHI1 54806 NM_001134830 /// NM_001134831 /// NM_001134832 /// NM_017651 /// XM_005267039 /// XM_006715507 /// XR_427973 0001738 // morphogenesis of a polarized epithelium // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0006903 // vesicle targeting // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030862 // positive regulation of polarized epithelial cell differentiation // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035844 // cloaca development // inferred from sequence or structural similarity /// 0035845 // photoreceptor cell outer segment organization // inferred from sequence or structural similarity /// 0039008 // pronephric nephron tubule morphogenesis // inferred from sequence or structural similarity /// 0039023 // pronephric duct morphogenesis // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0065001 // specification of axis polarity // inferred from sequence or structural similarity /// 0070121 // Kupffer's vesicle development // inferred from sequence or structural similarity /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071599 // otic vesicle development // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220843_s_at NM_014156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014156.1 /DEF=Homo sapiens DKFZP564O0463 protein (DKFZP564O0463), mRNA. /FEA=mRNA /GEN=DKFZP564O0463 /PROD=HSPC064 protein /DB_XREF=gi:7661767 /UG=Hs.273344 DKFZP564O0463 protein /FL=gb:AF161549.1 gb:NM_014156.1 NM_014156 DDB1 and CUL4 associated factor 13 DCAF13 25879 NM_015420 0006364 // rRNA processing // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220844_at NM_016427 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016427.1 /DEF=Homo sapiens transcription elongation factor (SIII) elongin A2 (TCEB3L), mRNA. /FEA=mRNA /GEN=TCEB3L /PROD=elongin A2 /DB_XREF=gi:7705978 /UG=Hs.274174 transcription elongation factor (SIII) elongin A2 /FL=gb:AB030834.1 gb:NM_016427.1 NM_016427 transcription elongation factor B polypeptide 3B (elongin A2) TCEB3B 51224 NM_016427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation 220845_at NM_018308 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018308.1 /DEF=Homo sapiens hypothetical protein FLJ11042 (FLJ11042), mRNA. /FEA=mRNA /GEN=FLJ11042 /PROD=hypothetical protein FLJ11042 /DB_XREF=gi:8922839 /UG=Hs.274208 hypothetical protein FLJ11042 /FL=gb:NM_018308.1 NM_018308 acyl-CoA oxidase-like ACOXL 55289 NM_001105516 /// NM_001142807 /// NM_001142808 /// NM_018308 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation 220846_s_at NM_018065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018065.1 /DEF=Homo sapiens hypothetical protein FLJ10346 (FLJ10346), mRNA. /FEA=mRNA /GEN=FLJ10346 /PROD=hypothetical protein FLJ10346 /DB_XREF=gi:8922363 /UG=Hs.274280 hypothetical protein FLJ10346 /FL=gb:NM_018065.1 NM_018065 uncharacterized LOC100506504 LOC100506504 100506504 XM_006710074 /// XM_006711074 220847_x_at NM_013359 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013359.1 /DEF=Homo sapiens zinc finger protein 221 (ZNF221), mRNA. /FEA=mRNA /GEN=ZNF221 /PROD=zinc finger protein 221 /DB_XREF=gi:7019584 /UG=Hs.274445 zinc finger protein 221 /FL=gb:AF187987.1 gb:NM_013359.1 NM_013359 zinc finger protein 221 ZNF221 7638 NM_013359 /// XM_005259206 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220848_x_at NM_014582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014582.1 /DEF=Homo sapiens odorant-binding protein 2A (OBP2A), mRNA. /FEA=mRNA /GEN=OBP2A /PROD=odorant-binding protein 2A /DB_XREF=gi:7657404 /UG=Hs.274480 odorant-binding protein 2A /FL=gb:NM_014582.1 NM_014582 odorant binding protein 2A OBP2A 29991 NM_001293189 /// NM_001293193 /// NM_014582 /// NR_120603 /// XM_006717087 0006810 // transport // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007635 // chemosensory behavior // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005549 // odorant binding // non-traceable author statement 220849_at NM_024934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024934.1 /DEF=Homo sapiens hypothetical protein FLJ22659 (FLJ22659), mRNA. /FEA=mRNA /GEN=FLJ22659 /PROD=hypothetical protein FLJ22659 /DB_XREF=gi:13376405 /UG=Hs.276833 hypothetical protein FLJ22659 /FL=gb:NM_024934.1 NM_024934 uncharacterized LOC79999 LOC79999 79999 NM_001291904 /// NM_024934 /// XR_429855 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030128 // clathrin coat of endocytic vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 220850_at NM_014429 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014429.1 /DEF=Homo sapiens microrchidia (mouse) homolog (MORC), mRNA. /FEA=mRNA /GEN=MORC /PROD=microrchidia (mouse) homolog /DB_XREF=gi:7657340 /UG=Hs.278908 microrchidia (mouse) homolog /FL=gb:AF084946.1 gb:NM_014429.1 NM_014429 MORC family CW-type zinc finger 1 MORC1 27136 NM_014429 /// XM_005247362 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220851_at NM_014095 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014095.1 /DEF=Homo sapiens PRO1600 protein (PRO1600), mRNA. /FEA=mRNA /GEN=PRO1600 /PROD=PRO1600 protein /DB_XREF=gi:7662601 /UG=Hs.278922 PRO1600 protein /FL=gb:AF118069.1 gb:NM_014095.1 NM_014095 Homo sapiens PRO1600 mRNA, complete cds. BC069756 220852_at NM_014099 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014099.1 /DEF=Homo sapiens PRO1768 protein (PRO1768), mRNA. /FEA=mRNA /GEN=PRO1768 /PROD=PRO1768 protein /DB_XREF=gi:7662610 /UG=Hs.278924 PRO1768 protein /FL=gb:AF118074.1 gb:NM_014099.1 NM_014099 FOXN3 antisense RNA 2 FOXN3-AS2 29018 NM_014099 /// NR_024620 220853_at NM_014118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014118.1 /DEF=Homo sapiens PRO0159 protein (PRO0159), mRNA. /FEA=mRNA /GEN=PRO0159 /PROD=PRO0159 protein /DB_XREF=gi:7662529 /UG=Hs.278931 PRO0159 protein /FL=gb:AF090899.1 gb:NM_014118.1 NM_014118 glycosyltransferase-like domain containing 1 GTDC1 79712 NM_001006636 /// NM_001164629 /// NM_001284233 /// NM_001284234 /// NM_001284235 /// NM_001284238 /// NM_024659 /// XM_005263771 /// XM_005263774 /// XM_005263775 /// XM_005263777 /// XM_005263782 /// XM_005263784 /// XM_005263786 /// XM_006712752 /// XM_006712753 /// XM_006712754 /// XM_006712755 /// XM_006712756 0009058 // biosynthetic process // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220854_at NM_014123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014123.1 /DEF=Homo sapiens PRO0246 protein (PRO0246), mRNA. /FEA=mRNA /GEN=PRO0246 /PROD=PRO0246 protein /DB_XREF=gi:7662539 /UG=Hs.278934 PRO0246 protein /FL=gb:AF090908.1 gb:NM_014123.1 NM_014123 220855_at NM_014127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014127.1 /DEF=Homo sapiens PRO0456 protein (PRO0456), mRNA. /FEA=mRNA /GEN=PRO0456 /PROD=PRO0456 protein /DB_XREF=gi:7662551 /UG=Hs.278936 PRO0456 protein /FL=gb:AF090926.1 gb:NM_014127.1 NM_014127 CLTC intronic transcript 1 (non-protein coding) CLTC-IT1 100506863 XR_158918 /// XR_159290 /// XR_172216 220856_x_at NM_014128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014128.1 /DEF=Homo sapiens PRO0470 protein (PRO0470), mRNA. /FEA=mRNA /GEN=PRO0470 /PROD=PRO0470 protein /DB_XREF=gi:7662555 /UG=Hs.278937 PRO0470 protein /FL=gb:AF090928.1 gb:NM_014128.1 NM_014128 220857_at NM_014131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014131.1 /DEF=Homo sapiens PRO0514 protein (PRO0514), mRNA. /FEA=mRNA /GEN=PRO0514 /PROD=PRO0514 protein /DB_XREF=gi:7662563 /UG=Hs.278939 PRO0514 protein /FL=gb:AF090933.1 gb:NM_014131.1 NM_014131 220858_at NM_014133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014133.1 /DEF=Homo sapiens PRO0618 protein (PRO0618), mRNA. /FEA=mRNA /GEN=PRO0618 /PROD=PRO0618 protein /DB_XREF=gi:7662573 /UG=Hs.278940 PRO0618 protein /FL=gb:AF090937.1 gb:NM_014133.1 NM_014133 sorbin and SH3 domain containing 2 SORBS2 8470 NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220859_at NM_014136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014136.1 /DEF=Homo sapiens PRO0644 protein (PRO0644), mRNA. /FEA=mRNA /GEN=PRO0644 /PROD=PRO0644 protein /DB_XREF=gi:7662579 /UG=Hs.278942 PRO0644 protein /FL=gb:AF090940.1 gb:NM_014136.1 NM_014136 220860_at NM_013357 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013357.1 /DEF=Homo sapiens Pur-gamma (PURG), mRNA. /FEA=mRNA /GEN=PURG /PROD=Pur-gamma /DB_XREF=gi:7019506 /UG=Hs.278953 Pur-gamma /FL=gb:AF195513.1 gb:NM_013357.1 NM_013357 purine-rich element binding protein G PURG 29942 NM_001015508 /// NM_013357 /// XM_005273483 /// XM_005273484 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220861_at AF118067 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF118067.1 /DEF=Homo sapiens PRO1578 mRNA, complete cds. /FEA=mRNA /PROD=PRO1578 /DB_XREF=gi:6650779 /UG=Hs.279380 PRO1578 protein /FL=gb:AF118067.1 gb:NM_014093.1 AF118067 ubiquitin specific peptidase 22 USP22 23326 NM_015276 /// XM_005256575 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220862_s_at NM_014093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014093.1 /DEF=Homo sapiens PRO1578 protein (PRO1578), mRNA. /FEA=mRNA /GEN=PRO1578 /PROD=PRO1578 protein /DB_XREF=gi:7662597 /UG=Hs.279380 PRO1578 protein /FL=gb:AF118067.1 gb:NM_014093.1 NM_014093 220863_at NM_012064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012064.1 /DEF=Homo sapiens major intrinsic protein of lens fiber (MIP), mRNA. /FEA=mRNA /GEN=MIP /PROD=major intrinsic protein of lens fiber /DB_XREF=gi:6912505 /UG=Hs.279561 major intrinsic protein of lens fiber /FL=gb:NM_012064.1 NM_012064 major intrinsic protein of lens fiber MIP 4284 NM_012064 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // inferred from sequence or structural similarity /// 0006833 // water transport // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0015722 // canalicular bile acid transport // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005921 // gap junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0046691 // intracellular canaliculus // inferred from electronic annotation 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015250 // water channel activity // inferred from sequence or structural similarity 220864_s_at NM_015965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015965.1 /DEF=Homo sapiens CGI-39 protein; cell death-regulatory protein GRIM19 (LOC51079), mRNA. /FEA=mRNA /GEN=LOC51079 /PROD=CGI-39 protein; cell death-regulatory proteinGRIM19 /DB_XREF=gi:7705733 /UG=Hs.279574 CGI-39 protein; cell death-regulatory protein GRIM19 /FL=gb:AF132973.1 gb:AF155662.1 gb:NM_015965.1 NM_015965 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 NDUFA13 51079 NM_015965 0006606 // protein import into nucleus // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045039 // protein import into mitochondrial inner membrane // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from direct assay 220865_s_at NM_014317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014317.2 /DEF=Homo sapiens trans-prenyltransferase (TPT), mRNA. /FEA=mRNA /GEN=TPT /PROD=trans-prenyltransferase /DB_XREF=gi:11863164 /UG=Hs.279865 trans-prenyltransferase /FL=gb:NM_014317.2 gb:AF118395.1 NM_014317 prenyl (decaprenyl) diphosphate synthase, subunit 1 PDSS1 23590 NM_014317 /// XM_005252439 /// XR_428636 0006744 // ubiquinone biosynthetic process // inferred from direct assay /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051290 // protein heterotetramerization // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000010 // trans-hexaprenyltranstransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0050347 // trans-octaprenyltranstransferase activity // inferred from electronic annotation 220866_at NM_014273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014273.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6 (ADAMTS6), mRNA. /FEA=mRNA /GEN=ADAMTS6 /PROD=a disintegrin and metalloprotease withthrombospondin motifs-6 preproprotein /DB_XREF=gi:7656868 /UG=Hs.279874 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6 /FL=gb:AF140674.1 gb:NM_014273.1 NM_014273 ADAM metallopeptidase with thrombospondin type 1 motif, 6 ADAMTS6 11174 NM_197941 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220867_s_at NM_020344 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020344.1 /DEF=Homo sapiens solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 2 (SLC24A2), mRNA. /FEA=mRNA /GEN=SLC24A2 /PROD=solute carrier family 24(sodiumpotassiumcalcium exchanger), member 2 /DB_XREF=gi:9966786 /UG=Hs.283014 solute carrier family 24 (sodiumpotassiumcalcium exchanger), member 2 /FL=gb:AF097366.1 gb:NM_020344.1 NM_020344 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 SLC24A2 25769 NM_001193288 /// NM_020344 /// XM_005251425 /// XM_005251426 /// XM_006716750 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from electronic annotation 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008273 // calcium, potassium:sodium antiporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 220868_s_at NM_017965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017965.1 /DEF=Homo sapiens hypothetical protein FLJ20839 (FLJ20839), mRNA. /FEA=mRNA /GEN=FLJ20839 /PROD=hypothetical protein FLJ20839 /DB_XREF=gi:8923692 /UG=Hs.283024 hypothetical protein FLJ20839 /FL=gb:NM_017965.1 NM_017965 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 SLC7A10 56301 NM_019849 /// XM_006723284 /// XM_006723285 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015804 // neutral amino acid transport // inferred from direct assay /// 0015825 // L-serine transport // traceable author statement /// 0042941 // D-alanine transport // inferred from electronic annotation /// 0042942 // D-serine transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from direct assay /// 0015194 // L-serine transmembrane transporter activity // traceable author statement 220869_at NM_018496 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018496.1 /DEF=Homo sapiens hypothetical protein PRO0889 (PRO0889), mRNA. /FEA=mRNA /GEN=PRO0889 /PROD=hypothetical protein PRO0889 /DB_XREF=gi:8923984 /UG=Hs.283025 hypothetical protein PRO0889 /FL=gb:AF119839.1 gb:NM_018496.1 NM_018496 ubiquitin-like modifier activating enzyme 6 UBA6 55236 NM_018227 /// XM_006714253 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019780 // FAT10 activating enzyme activity // inferred from mutant phenotype 220870_at NM_018503 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018503.1 /DEF=Homo sapiens hypothetical protein PRO1598 (PRO1598), mRNA. /FEA=mRNA /GEN=PRO1598 /PROD=hypothetical protein PRO1598 /DB_XREF=gi:8924062 /UG=Hs.283028 hypothetical protein PRO1598 /FL=gb:AF119849.1 gb:NM_018503.1 NM_018503 220871_at NM_018513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018513.1 /DEF=Homo sapiens hypothetical protein PRO2130 (PRO2130), mRNA. /FEA=mRNA /GEN=PRO2130 /PROD=hypothetical protein PRO2130 /DB_XREF=gi:8924119 /UG=Hs.283033 hypothetical protein PRO2130 /FL=gb:AF119862.1 gb:NM_018513.1 NM_018513 220872_at NM_018547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018547.1 /DEF=Homo sapiens hypothetical protein PRO2964 (PRO2964), mRNA. /FEA=mRNA /GEN=PRO2964 /PROD=hypothetical protein PRO2964 /DB_XREF=gi:8924224 /UG=Hs.283047 hypothetical protein PRO2964 /FL=gb:AF119910.1 gb:NM_018547.1 NM_018547 uncharacterized protein PRO2964 PRO2964 55415 220873_at NM_018562 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018562.1 /DEF=Homo sapiens hypothetical protein PRO0386 (PRO0386), mRNA. /FEA=mRNA /GEN=PRO0386 /PROD=hypothetical protein PRO0386 /DB_XREF=gi:8923971 /UG=Hs.283049 hypothetical protein PRO0386 /FL=gb:AF116603.1 gb:NM_018562.1 NM_018562 220874_at NM_018575 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018575.1 /DEF=Homo sapiens hypothetical protein PR01094 (PR01094), mRNA. /FEA=mRNA /GEN=PR01094 /PROD=hypothetical protein PR01094 /DB_XREF=gi:8923961 /UG=Hs.283052 hypothetical protein PR01094 /FL=gb:AF116623.1 gb:NM_018575.1 NM_018575 220875_at NM_018576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018576.1 /DEF=Homo sapiens hypothetical protein PRO1163 (PRO1163), mRNA. /FEA=mRNA /GEN=PRO1163 /PROD=hypothetical protein PRO1163 /DB_XREF=gi:8924019 /UG=Hs.283053 hypothetical protein PRO1163 /FL=gb:AF116626.1 gb:NM_018576.1 NM_018576 220876_at NM_018578 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018578.1 /DEF=Homo sapiens hypothetical protein PRO1257 (PRO1257), mRNA. /FEA=mRNA /GEN=PRO1257 /PROD=hypothetical protein PRO1257 /DB_XREF=gi:8924025 /UG=Hs.283054 hypothetical protein PRO1257 /FL=gb:AF116629.1 gb:NM_018578.1 NM_018578 220877_at NM_018580 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018580.1 /DEF=Homo sapiens hypothetical protein PRO1316 (PRO1316), mRNA. /FEA=mRNA /GEN=PRO1316 /PROD=hypothetical protein PRO1316 /DB_XREF=gi:8924031 /UG=Hs.283055 hypothetical protein PRO1316 /FL=gb:AF116632.1 gb:NM_018580.1 NM_018580 220878_at NM_018592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018592.1 /DEF=Homo sapiens hypothetical protein PRO0800 (PRO0800), mRNA. /FEA=mRNA /GEN=PRO0800 /PROD=hypothetical protein PRO0800 /DB_XREF=gi:8923978 /UG=Hs.283058 hypothetical protein PRO0800 /FL=gb:AF116651.1 gb:NM_018592.1 NM_018592 220879_at NM_018600 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018600.1 /DEF=Homo sapiens hypothetical protein PRO1438 (PRO1438), mRNA. /FEA=mRNA /GEN=PRO1438 /PROD=hypothetical protein PRO1438 /DB_XREF=gi:8924039 /UG=Hs.283061 hypothetical protein PRO1438 /FL=gb:AF116661.1 gb:NM_018600.1 NM_018600 220880_at NM_018601 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018601.1 /DEF=Homo sapiens hypothetical protein PRO1446 (PRO1446), mRNA. /FEA=mRNA /GEN=PRO1446 /PROD=hypothetical protein PRO1446 /DB_XREF=gi:8924041 /UG=Hs.283062 hypothetical protein PRO1446 /FL=gb:AF116662.1 gb:NM_018601.1 NM_018601 220881_at NM_018606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018606.1 /DEF=Homo sapiens hypothetical protein PRO1787 (PRO1787), mRNA. /FEA=mRNA /GEN=PRO1787 /PROD=hypothetical protein PRO1787 /DB_XREF=gi:8924080 /UG=Hs.283063 hypothetical protein PRO1787 /FL=gb:AF116668.1 gb:NM_018606.1 NM_018606 220882_at NM_018612 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018612.1 /DEF=Homo sapiens hypothetical protein PRO1995 (PRO1995), mRNA. /FEA=mRNA /GEN=PRO1995 /PROD=hypothetical protein PRO1995 /DB_XREF=gi:8924103 /UG=Hs.283064 hypothetical protein PRO1995 /FL=gb:AF116678.1 gb:NM_018612.1 NM_018612 220883_at NM_018614 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018614.1 /DEF=Homo sapiens hypothetical protein PRO2012 (PRO2012), mRNA. /FEA=mRNA /GEN=PRO2012 /PROD=hypothetical protein PRO2012 /DB_XREF=gi:8924107 /UG=Hs.283066 hypothetical protein PRO2012 /FL=gb:AF116681.1 gb:NM_018614.1 NM_018614 uncharacterized protein PRO2012 PRO2012 55478 220884_at NM_018633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018633.1 /DEF=Homo sapiens hypothetical protein PRO2796 (PRO2796), mRNA. /FEA=mRNA /GEN=PRO2796 /PROD=hypothetical protein PRO2796 /DB_XREF=gi:8924199 /UG=Hs.283071 hypothetical protein PRO2796 /FL=gb:AF116714.1 gb:NM_018633.1 NM_018633 220885_s_at NM_018451 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018451.1 /DEF=Homo sapiens centrosomal P4.1-associated protein; uncharacterized bone marrow protein BM032 (BM032), mRNA. /FEA=mRNA /GEN=BM032 /PROD=centrosomal P4.1-associated protein;uncharacterized bone marrow protein BM032 /DB_XREF=gi:8922088 /UG=Hs.283077 centrosomal P4.1-associated protein; uncharacterized bone marrow protein BM032 /FL=gb:AF217509.1 gb:NM_018451.1 NM_018451 centromere protein J CENPJ 55835 NM_018451 /// NR_047594 /// NR_047595 /// XR_429218 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement /// 0007099 // centriole replication // inferred from mutant phenotype /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0046785 // microtubule polymerization // inferred from mutant phenotype /// 0051301 // cell division // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0008275 // gamma-tubulin small complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 220886_at NM_018558 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018558.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) receptor, theta (GABRQ), mRNA. /FEA=mRNA /GEN=GABRQ /PROD=gamma-aminobutyric acid (GABA) receptor, thetaprecursor /DB_XREF=gi:8924257 /UG=Hs.283081 gamma-aminobutyric acid (GABA) receptor, theta /FL=gb:AF144648.1 gb:AF189259.1 gb:NM_018558.1 NM_018558 gamma-aminobutyric acid (GABA) A receptor, theta GABRQ 55879 NM_018558 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005326 // neurotransmitter transporter activity // traceable author statement 220887_at NM_020181 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020181.1 /DEF=Homo sapiens myelin proteolipid protein-like protein (PLPL), mRNA. /FEA=mRNA /GEN=PLPL /PROD=myelin proteolipid protein-like protein /DB_XREF=gi:9910495 /UG=Hs.283094 myelin proteolipid protein-like protein /FL=gb:AF284217.1 gb:NM_020181.1 NM_020181 coiled-coil domain containing 177 CCDC177 56936 NM_001271507 /// NM_020181 /// NR_024630 220888_s_at NM_020356 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020356.1 /DEF=Homo sapiens HEF like Protein (HEFL), mRNA. /FEA=mRNA /GEN=HEFL /PROD=HEF like Protein /DB_XREF=gi:9966824 /UG=Hs.283102 HEF like Protein /FL=gb:NM_020356.1 NM_020356 Cas scaffolding protein family member 4 CASS4 57091 NM_001164114 /// NM_001164115 /// NM_001164116 /// NM_020356 /// XM_006723831 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0000155 // phosphorelay sensor kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220889_s_at NM_020178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020178.1 /DEF=Homo sapiens Carbonic anhydrase-related protein 10 (LOC56934), mRNA. /FEA=mRNA /GEN=LOC56934 /PROD=Carbonic anhydrase-related protein 10 /DB_XREF=gi:9910365 /UG=Hs.283110 Carbonic anhydrase-related protein 10 /FL=gb:AB036836.1 gb:NM_020178.1 NM_020178 carbonic anhydrase X CA10 56934 NM_001082533 /// NM_001082534 /// NM_020178 /// XM_005257523 0007420 // brain development // non-traceable author statement 220890_s_at NM_016355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016355.1 /DEF=Homo sapiens hqp0256 protein (LOC51202), mRNA. /FEA=mRNA /GEN=LOC51202 /PROD=hqp0256 protein /DB_XREF=gi:10047107 /UG=Hs.284288 hqp0256 protein /FL=gb:NM_016355.1 gb:AF078843.1 NM_016355 apolipoprotein L domain containing 1 /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 APOLD1 /// DDX47 51202 /// 81575 NM_001130415 /// NM_016355 /// NM_030817 /// NM_201224 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0016070 // RNA metabolic process // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0045601 // regulation of endothelial cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220891_at NM_024950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024950.1 /DEF=Homo sapiens hypothetical protein FLJ12891 (FLJ12891), mRNA. /FEA=mRNA /GEN=FLJ12891 /PROD=hypothetical protein FLJ12891 /DB_XREF=gi:13376434 /UG=Hs.285317 hypothetical protein FLJ12891 /FL=gb:NM_024950.1 NM_024950 tRNA methyltransferase 44 homolog (S. cerevisiae) TRMT44 152992 NM_001031742 /// NM_024950 /// NM_152544 /// XM_005247950 /// XM_006713862 /// XR_427468 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220892_s_at NM_021154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021154.1 /DEF=Homo sapiens phosphoserine aminotransferase (PSA), mRNA. /FEA=mRNA /GEN=PSA /PROD=phosphoserine aminotransferase /DB_XREF=gi:10863954 /UG=Hs.286049 phosphoserine aminotransferase /FL=gb:NM_021154.1 gb:AF113132.1 NM_021154 phosphoserine aminotransferase 1 PSAT1 29968 NM_021154 /// NM_058179 0006564 // L-serine biosynthetic process // non-traceable author statement /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008615 // pyridoxine biosynthetic process // non-traceable author statement /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004648 // O-phospho-L-serine:2-oxoglutarate aminotransferase activity // non-traceable author statement /// 0004648 // O-phospho-L-serine:2-oxoglutarate aminotransferase activity // traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 220893_at NM_020669 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020669.1 /DEF=Homo sapiens uncharacterized gastric protein ZA52P (LOC57399), mRNA. /FEA=mRNA /GEN=LOC57399 /PROD=uncharacterized gastric protein ZA52P /DB_XREF=gi:10190709 /UG=Hs.287376 uncharacterized gastric protein ZA52P /FL=gb:NM_020669.1 gb:AF264626.1 NM_020669 uncharacterized gastric protein ZA52P LOC57399 57399 NM_020669 /// XM_926542 220894_x_at NM_021619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021619.1 /DEF=Homo sapiens PR domain containing 12 (PRDM12), mRNA. /FEA=mRNA /GEN=PRDM12 /PROD=PR domain containing 12 /DB_XREF=gi:11055979 /UG=Hs.287385 PR domain containing 12 /FL=gb:AY004252.1 gb:NM_021619.1 NM_021619 PR domain containing 12 PRDM12 59335 NM_021619 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220895_at NM_020903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020903.1 /DEF=Homo sapiens ubiquitin-specific processing protease (LOC57663), mRNA. /FEA=mRNA /GEN=LOC57663 /PROD=ubiquitin-specific processing protease /DB_XREF=gi:10190741 /UG=Hs.287405 ubiquitin-specific processing protease /FL=gb:NM_020903.1 gb:AF229438.1 NM_020903 ubiquitin specific peptidase 29 USP29 57663 NM_020903 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 220896_at NM_024963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024963.1 /DEF=Homo sapiens hypothetical protein FLJ11467 (FLJ11467), mRNA. /FEA=mRNA /GEN=FLJ11467 /PROD=hypothetical protein FLJ11467 /DB_XREF=gi:13489078 /UG=Hs.287418 hypothetical protein FLJ11467 /FL=gb:NM_024963.1 NM_024963 F-box and leucine-rich repeat protein 18 FBXL18 80028 NM_024963 /// XM_005249853 /// XM_005249854 0016021 // integral component of membrane // inferred from electronic annotation 220897_at NM_024964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024964.1 /DEF=Homo sapiens hypothetical protein FLJ11556 (FLJ11556), mRNA. /FEA=mRNA /GEN=FLJ11556 /PROD=hypothetical protein FLJ11556 /DB_XREF=gi:13376454 /UG=Hs.287423 hypothetical protein FLJ11556 /FL=gb:NM_024964.1 NM_024964 220898_at NM_024972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024972.1 /DEF=Homo sapiens hypothetical protein FLJ11736 (FLJ11736), mRNA. /FEA=mRNA /GEN=FLJ11736 /PROD=hypothetical protein FLJ11736 /DB_XREF=gi:13376469 /UG=Hs.287448 hypothetical protein FLJ11736 /FL=gb:NM_024972.1 NM_024972 220899_at NM_024973 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024973.1 /DEF=Homo sapiens hypothetical protein FLJ11781 (FLJ11781), mRNA. /FEA=mRNA /GEN=FLJ11781 /PROD=hypothetical protein FLJ11781 /DB_XREF=gi:13376471 /UG=Hs.287455 hypothetical protein FLJ11781 /FL=gb:NM_024973.1 NM_024973 220900_at NM_024977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024977.1 /DEF=Homo sapiens hypothetical protein FLJ12078 (FLJ12078), mRNA. /FEA=mRNA /GEN=FLJ12078 /PROD=hypothetical protein FLJ12078 /DB_XREF=gi:13376477 /UG=Hs.287483 hypothetical protein FLJ12078 /FL=gb:NM_024977.1 NM_024977 RP11-549J18.1 220901_at NM_024980 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024980.1 /DEF=Homo sapiens hypothetical protein FLJ12132 (FLJ12132), mRNA. /FEA=mRNA /GEN=FLJ12132 /PROD=hypothetical protein FLJ12132 /DB_XREF=gi:13376483 /UG=Hs.287490 hypothetical protein FLJ12132 /FL=gb:NM_024980.1 NM_024980 G protein-coupled receptor 157 GPR157 80045 NM_024980 /// XM_005263496 /// XM_005263497 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220902_at NM_024995 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024995.1 /DEF=Homo sapiens hypothetical protein FLJ12616 (FLJ12616), mRNA. /FEA=mRNA /GEN=FLJ12616 /PROD=hypothetical protein FLJ12616 /DB_XREF=gi:13376501 /UG=Hs.287537 hypothetical protein FLJ12616 /FL=gb:NM_024995.1 NM_024995 220903_at NM_024996 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024996.1 /DEF=Homo sapiens hypothetical protein FLJ12662 (FLJ12662), mRNA. /FEA=mRNA /GEN=FLJ12662 /PROD=hypothetical protein FLJ12662 /DB_XREF=gi:13376503 /UG=Hs.287539 hypothetical protein FLJ12662 /FL=gb:NM_024996.1 NM_024996 G elongation factor, mitochondrial 1 GFM1 85476 NM_024996 /// XM_006713795 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0070125 // mitochondrial translational elongation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220904_at NM_025002 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025002.1 /DEF=Homo sapiens hypothetical protein FLJ13162 (FLJ13162), mRNA. /FEA=mRNA /GEN=FLJ13162 /PROD=hypothetical protein FLJ13162 /DB_XREF=gi:13376514 /UG=Hs.287553 hypothetical protein FLJ13162 /FL=gb:NM_025002.1 NM_025002 long intergenic non-protein coding RNA 574 LINC00574 80069 NM_025002 /// NR_026780 220905_at NM_025007 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025007.1 /DEF=Homo sapiens hypothetical protein FLJ13501 (FLJ13501), mRNA. /FEA=mRNA /GEN=FLJ13501 /PROD=hypothetical protein FLJ13501 /DB_XREF=gi:13376524 /UG=Hs.287576 hypothetical protein FLJ13501 /FL=gb:NM_025007.1 NM_025007 220906_at NM_025016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025016.1 /DEF=Homo sapiens hypothetical protein FLJ13885 (FLJ13885), mRNA. /FEA=mRNA /GEN=FLJ13885 /PROD=hypothetical protein FLJ13885 /DB_XREF=gi:13376534 /UG=Hs.287607 hypothetical protein FLJ13885 /FL=gb:NM_025016.1 NM_025016 220907_at NM_025048 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025048.1 /DEF=Homo sapiens hypothetical protein FLJ22684 (FLJ22684), mRNA. /FEA=mRNA /GEN=FLJ22684 /PROD=hypothetical protein FLJ22684 /DB_XREF=gi:13376575 /UG=Hs.287710 hypothetical protein FLJ22684 /FL=gb:NM_025048.1 NM_025048 G protein-coupled receptor 110 GPR110 266977 NM_025048 /// NM_153840 /// XM_005249005 /// XM_005249006 /// XM_006715058 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220908_at NM_025055 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025055.1 /DEF=Homo sapiens hypothetical protein FLJ23168 (FLJ23168), mRNA. /FEA=mRNA /GEN=FLJ23168 /PROD=hypothetical protein FLJ23168 /DB_XREF=gi:13376586 /UG=Hs.287731 hypothetical protein FLJ23168 /FL=gb:NM_025055.1 NM_025055 coiled-coil domain containing 33 CCDC33 80125 NM_001287181 /// NM_025055 /// NM_182791 /// NR_108023 /// XM_005254692 /// XM_006720697 /// XM_006720698 0005515 // protein binding // inferred from physical interaction 220909_at NM_025058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025058.1 /DEF=Homo sapiens hypothetical protein FLJ23229 (FLJ23229), mRNA. /FEA=mRNA /GEN=FLJ23229 /PROD=hypothetical protein FLJ23229 /DB_XREF=gi:13376592 /UG=Hs.287735 hypothetical protein FLJ23229 /FL=gb:NM_025058.1 NM_025058 tripartite motif containing 46 TRIM46 80128 NM_001256599 /// NM_001256600 /// NM_001256601 /// NM_001282378 /// NM_001282379 /// NM_025058 /// NR_046327 /// NR_046329 /// NR_104150 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220910_at NM_025074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025074.1 /DEF=Homo sapiens hypothetical protein FLJ22031 (FLJ22031), mRNA. /FEA=mRNA /GEN=FLJ22031 /PROD=hypothetical protein FLJ22031 /DB_XREF=gi:13376620 /UG=Hs.288119 hypothetical protein FLJ22031 /FL=gb:NM_025074.1 NM_025074 Fraser extracellular matrix complex subunit 1 FRAS1 80144 NM_001166133 /// NM_020875 /// NM_025074 /// NM_032863 /// NM_206841 /// XM_006714314 /// XM_006714315 /// XM_006714316 /// XM_006714317 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0061618 // sublamina densa // inferred from sequence or structural similarity 0046872 // metal ion binding // inferred from electronic annotation 220911_s_at NM_025081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025081.1 /DEF=Homo sapiens KIAA1305 protein (KIAA1305), mRNA. /FEA=mRNA /GEN=KIAA1305 /PROD=hypothetical protein FLJ11811 /DB_XREF=gi:13378146 /UG=Hs.288348 KIAA1305 protein /FL=gb:NM_025081.1 NM_025081 NYN domain and retroviral integrase containing NYNRIN 57523 NM_025081 0015074 // DNA integration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 220912_at NM_025093 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025093.1 /DEF=Homo sapiens hypothetical protein FLJ11827 (FLJ11827), mRNA. /FEA=mRNA /GEN=FLJ11827 /PROD=hypothetical protein FLJ11827 /DB_XREF=gi:13376653 /UG=Hs.288534 hypothetical protein FLJ11827 /FL=gb:NM_025093.1 NM_025093 220913_at NM_025102 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025102.1 /DEF=Homo sapiens hypothetical protein FLJ21497 (FLJ21497), mRNA. /FEA=mRNA /GEN=FLJ21497 /PROD=hypothetical protein FLJ21497 /DB_XREF=gi:13443021 /UG=Hs.288596 hypothetical protein FLJ21497 /FL=gb:NM_025102.1 NM_025102 220914_at NM_025117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025117.1 /DEF=Homo sapiens hypothetical protein FLJ11871 (FLJ11871), mRNA. /FEA=mRNA /GEN=FLJ11871 /PROD=hypothetical protein FLJ11871 /DB_XREF=gi:13376694 /UG=Hs.288727 hypothetical protein FLJ11871 /FL=gb:NM_025117.1 NM_025117 Homo sapiens cDNA FLJ11871 fis, clone HEMBA1007052. AK021933 220915_s_at NM_025117 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025117.1 /DEF=Homo sapiens hypothetical protein FLJ11871 (FLJ11871), mRNA. /FEA=mRNA /GEN=FLJ11871 /PROD=hypothetical protein FLJ11871 /DB_XREF=gi:13376694 /UG=Hs.288727 hypothetical protein FLJ11871 /FL=gb:NM_025117.1 NM_025117 Homo sapiens cDNA FLJ11871 fis, clone HEMBA1007052. AK021933 220916_at NM_025118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025118.1 /DEF=Homo sapiens hypothetical protein FLJ13310 (FLJ13310), mRNA. /FEA=mRNA /GEN=FLJ13310 /PROD=hypothetical protein FLJ13310 /DB_XREF=gi:13376696 /UG=Hs.288731 hypothetical protein FLJ13310 /FL=gb:NM_025118.1 NM_025118 220917_s_at NM_025132 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025132.1 /DEF=Homo sapiens KIAA1638 protein (KIAA1638), mRNA. /FEA=mRNA /GEN=KIAA1638 /PROD=hypothetical protein FLJ23127 /DB_XREF=gi:13386465 /UG=Hs.288821 KIAA1638 protein /FL=gb:NM_025132.1 NM_025132 WD repeat domain 19 WDR19 57728 NM_025132 /// XM_005262658 /// XM_006714025 /// XM_006714026 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0035721 // intraciliary retrograde transport // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050877 // neurological system process // inferred from electronic annotation /// 0055123 // digestive system development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060830 // ciliary receptor clustering involved in smoothened signaling pathway // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0061055 // myotome development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 220918_at NM_025143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025143.1 /DEF=Homo sapiens hypothetical protein FLJ20856 (FLJ20856), mRNA. /FEA=mRNA /GEN=FLJ20856 /PROD=hypothetical protein FLJ20856 /DB_XREF=gi:13376728 /UG=Hs.288916 hypothetical protein FLJ20856 /FL=gb:NM_025143.1 NM_025143 RUNX1 intronic transcript 1 (non-protein coding) RUNX1-IT1 80215 NM_025143 /// NR_026812 0005829 // cytosol // inferred from direct assay 220919_s_at NM_025145 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025145.1 /DEF=Homo sapiens hypothetical protein FLJ22944 (FLJ22944), mRNA. /FEA=mRNA /GEN=FLJ22944 /PROD=hypothetical protein FLJ22944 /DB_XREF=gi:13376732 /UG=Hs.288927 hypothetical protein FLJ22944 /FL=gb:NM_025145.1 NM_025145 WD repeat domain 96 WDR96 80217 NM_025145 /// XM_005270171 /// XM_005270172 /// XM_005270173 /// XM_005270174 /// XM_005270175 /// XM_005270176 0005515 // protein binding // inferred from electronic annotation 220920_at NM_025153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025153.1 /DEF=Homo sapiens hypothetical protein FLJ21477 (FLJ21477), mRNA. /FEA=mRNA /GEN=FLJ21477 /PROD=hypothetical protein FLJ21477 /DB_XREF=gi:13376748 /UG=Hs.288983 hypothetical protein FLJ21477 /FL=gb:NM_025153.1 NM_025153 ATPase, class V, type 10B ATP10B 23120 NM_025153 /// XM_005265849 /// XM_006714833 0006810 // transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0045332 // phospholipid translocation // non-traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004012 // phospholipid-translocating ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220921_at NM_013453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013453.1 /DEF=Homo sapiens sperm protein associated with the nucleus, X chromosome, family member A1 (SPANXA1), mRNA. /FEA=mRNA /GEN=SPANXA1 /PROD=sperm protein associated with the nucleus, Xchromosome, family member A1 /DB_XREF=gi:7305516 /UG=Hs.293266 sperm protein associated with the nucleus, X chromosome, family member A1 /FL=gb:AF098307.1 gb:NM_013453.1 NM_013453 SPANX family, member B1 SPANXB1 728695 NM_032461 /// NM_145664 0007286 // spermatid development // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 220922_s_at NM_013453 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013453.1 /DEF=Homo sapiens sperm protein associated with the nucleus, X chromosome, family member A1 (SPANXA1), mRNA. /FEA=mRNA /GEN=SPANXA1 /PROD=sperm protein associated with the nucleus, Xchromosome, family member A1 /DB_XREF=gi:7305516 /UG=Hs.293266 sperm protein associated with the nucleus, X chromosome, family member A1 /FL=gb:AF098307.1 gb:NM_013453.1 NM_013453 sperm protein associated with the nucleus, X-linked, family member A1 /// SPANX family, member A2 /// SPANX family, member B1 /// SPANX family, member C SPANXA1 /// SPANXA2 /// SPANXB1 /// SPANXC 30014 /// 64663 /// 728695 /// 728712 NM_013453 /// NM_022661 /// NM_032461 /// NM_145662 /// NM_145664 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 220923_s_at NM_013364 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013364.1 /DEF=Homo sapiens paraneoplastic cancer-testis-brain antigen (MA5), mRNA. /FEA=mRNA /GEN=MA5 /PROD=paraneoplastic cancer-testis-brain antigen /DB_XREF=gi:7019450 /UG=Hs.296436 paraneoplastic cancer-testis-brain antigen /FL=gb:AF083116.1 gb:NM_013364.1 NM_013364 paraneoplastic Ma antigen 3 PNMA3 29944 NM_001282535 /// NM_013364 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220924_s_at NM_018976 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018976.1 /DEF=Homo sapiens amino acid transporter 2 (KIAA1382), mRNA. /FEA=mRNA /GEN=KIAA1382 /PROD=amino acid transporter 2 /DB_XREF=gi:9506836 /UG=Hs.298275 amino acid transporter 2 /FL=gb:NM_018976.1 NM_018976 solute carrier family 38, member 2 SLC38A2 54407 NM_018976 /// XM_005268983 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006865 // amino acid transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 220925_at NM_021929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021929.1 /DEF=Homo sapiens hypothetical protein FLJ21613 similar to rat corneal wound healing related protein (FLJ21613), mRNA. /FEA=mRNA /GEN=FLJ21613 /PROD=hypothetical protein FLJ21613 similar to ratcorneal wound healing related protein /DB_XREF=gi:11345463 /UG=Hs.300952 hypothetical protein FLJ21613 similar to rat corneal wound healing related protein /FL=gb:NM_021929.1 NM_021929 N(alpha)-acetyltransferase 35, NatC auxiliary subunit NAA35 60560 NM_024635 /// XM_005252126 /// XM_005252127 /// XM_005252128 /// XM_006717231 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0048659 // smooth muscle cell proliferation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005844 // polysome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031417 // NatC complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation 220926_s_at NM_025191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025191.1 /DEF=Homo sapiens hypothetical protein FLJ13033 (FLJ13033), mRNA. /FEA=mRNA /GEN=FLJ13033 /PROD=hypothetical protein FLJ13033 /DB_XREF=gi:13376781 /UG=Hs.301997 hypothetical protein FLJ13033 /FL=gb:NM_025191.1 NM_025191 ER degradation enhancer, mannosidase alpha-like 3 EDEM3 80267 NM_025191 /// XM_005245499 0006457 // protein folding // traceable author statement /// 0006516 // glycoprotein catabolic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0004569 // glycoprotein endo-alpha-1,2-mannosidase activity // inferred from electronic annotation /// 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220927_s_at NM_021828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021828.1 /DEF=Homo sapiens heparanase-like protein (HPA2), mRNA. /FEA=mRNA /GEN=HPA2 /PROD=heparanase-like protein /DB_XREF=gi:11141906 /UG=Hs.302018 heparanase-like protein /FL=gb:AF282887.1 gb:NM_021828.1 NM_021828 heparanase 2 (inactive) HPSE2 60495 NM_001166244 /// NM_001166245 /// NM_001166246 /// NM_021828 /// XM_006717937 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005622 // intracellular // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030305 // heparanase activity // inferred from direct assay /// 0030305 // heparanase activity // traceable author statement /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay 220928_s_at NM_022114 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022114.1 /DEF=Homo sapiens PR domain containing 16 (PRDM16), mRNA. /FEA=mRNA /GEN=PRDM16 /PROD=PR domain containing 16 /DB_XREF=gi:11545830 /UG=Hs.302022 PR domain containing 16 /FL=gb:AF294278.1 gb:NM_022114.1 NM_022114 PR domain containing 16 PRDM16 63976 NM_022114 /// NM_199454 /// XM_005244772 /// XM_005244773 /// XM_005244774 /// XM_006710814 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043457 // regulation of cellular respiration // inferred from sequence or structural similarity /// 0043586 // tongue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220929_at NM_017417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017417.1 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8) (GALNT8), mRNA. /FEA=mRNA /GEN=GALNT8 /PROD=polypeptide N-acetylgalactosaminyltransferase 8 /DB_XREF=gi:8393411 /UG=Hs.306190 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8) /FL=gb:NM_017417.1 NM_017417 polypeptide N-acetylgalactosaminyltransferase 8 GALNT8 26290 NM_017417 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220930_s_at NM_024058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024058.1 /DEF=Homo sapiens hypothetical protein MGC5590 (MGC5590), mRNA. /FEA=mRNA /GEN=MGC5590 /PROD=hypothetical protein MGC5590 /DB_XREF=gi:13129029 /UG=Hs.306224 hypothetical protein MGC5590 /FL=gb:BC000868.1 gb:NM_024058.1 NM_024058 small integral membrane protein 2 SMIM2 79024 NM_024058 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220931_at NM_024058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024058.1 /DEF=Homo sapiens hypothetical protein MGC5590 (MGC5590), mRNA. /FEA=mRNA /GEN=MGC5590 /PROD=hypothetical protein MGC5590 /DB_XREF=gi:13129029 /UG=Hs.306224 hypothetical protein MGC5590 /FL=gb:BC000868.1 gb:NM_024058.1 NM_024058 small integral membrane protein 2 SMIM2 79024 NM_024058 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220932_at NM_024073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024073.1 /DEF=Homo sapiens hypothetical protein MGC2875 (MGC2875), mRNA. /FEA=mRNA /GEN=MGC2875 /PROD=hypothetical protein MGC2875 /DB_XREF=gi:13129057 /UG=Hs.306225 hypothetical protein MGC2875 /FL=gb:BC001137.1 gb:NM_024073.1 NM_024073 220933_s_at NM_024617 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024617.1 /DEF=Homo sapiens hypothetical protein FLJ13409 (FLJ13409), mRNA. /FEA=mRNA /GEN=FLJ13409 /PROD=hypothetical protein FLJ13409 /DB_XREF=gi:13375835 /UG=Hs.30732 hypothetical protein FLJ13409; KIAA1711 protein /FL=gb:NM_024617.1 NM_024617 zinc finger, CCHC domain containing 6 ZCCHC6 79670 NM_001185059 /// NM_001185074 /// NM_024617 /// XM_005252207 /// XM_005252208 /// XM_005252209 /// XM_006717283 /// XM_006717284 /// XM_006717285 /// XM_006717286 0031123 // RNA 3'-end processing // inferred from direct assay /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050265 // RNA uridylyltransferase activity // inferred from direct assay 220934_s_at NM_024084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024084.1 /DEF=Homo sapiens hypothetical protein MGC3196 (MGC3196), mRNA. /FEA=mRNA /GEN=MGC3196 /PROD=hypothetical protein MGC3196 /DB_XREF=gi:13129079 /UG=Hs.309161 hypothetical protein MGC3196 /FL=gb:BC001204.1 gb:NM_024084.1 NM_024084 transmembrane protein 223 TMEM223 79064 NM_001080501 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220935_s_at NM_018249 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018249.1 /DEF=Homo sapiens hypothetical protein FLJ10867 (FLJ10867), mRNA. /FEA=mRNA /GEN=FLJ10867 /PROD=hypothetical protein FLJ10867 /DB_XREF=gi:8922723 /UG=Hs.32360 hypothetical protein FLJ10867 /FL=gb:NM_018249.1 NM_018249 CDK5 regulatory subunit associated protein 2 CDK5RAP2 55755 NM_001011649 /// NM_001272039 /// NM_018249 /// NR_073554 /// NR_073555 /// NR_073556 /// NR_073557 /// NR_073558 /// XM_006717179 /// XM_006717180 /// XM_006717181 /// XM_006717182 /// XM_006717183 /// XM_006717184 /// XM_006717185 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from sequence or structural similarity /// 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001578 // microtubule bundle formation // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007420 // brain development // non-traceable author statement /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0045664 // regulation of neuron differentiation // non-traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046600 // negative regulation of centriole replication // inferred from sequence or structural similarity /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0090231 // regulation of spindle checkpoint // inferred from direct assay 0000242 // pericentriolar material // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 220936_s_at NM_018267 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018267.1 /DEF=Homo sapiens hypothetical protein FLJ10903 (FLJ10903), mRNA. /FEA=mRNA /GEN=FLJ10903 /PROD=hypothetical protein FLJ10903 /DB_XREF=gi:8922757 /UG=Hs.36727 hypothetical protein FLJ10903 /FL=gb:NM_018267.1 NM_018267 H2A histone family, member J H2AFJ 55766 NM_018267 /// NM_177925 /// NR_027716 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 220937_s_at NM_014403 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014403.1 /DEF=Homo sapiens NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2, 6-sialyltransferase alpha2,6-sialyltransferase (ST6GALNACIV), mRNA. /FEA=mRNA /GEN=ST6GALNACIV /PROD=NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase alpha2,6-sialyltransferase /DB_XREF=gi:7657622 /UG=Hs.3972 NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2, 6-sialyltransferase alpha2,6-sialyltransferase /FL=gb:AF127142.1 gb:NM_014403.1 NM_014403 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6GALNAC4 27090 NM_014403 /// NM_175039 /// NM_175040 /// XM_005251922 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047290 // (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity // inferred from electronic annotation 220938_s_at NM_006582 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006582.2 /DEF=Homo sapiens glucocorticoid modulatory element binding protein 1 (GMEB1), transcript variant 1, mRNA. /FEA=mRNA /GEN=GMEB1 /PROD=glucocorticoid modulatory element bindingprotein 1, isoform 1 /DB_XREF=gi:13435376 /UG=Hs.4069 glucocorticoid modulatory element binding protein 1 /FL=gb:NM_006582.2 gb:AF099013.1 NM_006582 glucocorticoid modulatory element binding protein 1 GMEB1 10691 NM_006582 /// NM_024482 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220939_s_at NM_017743 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017743.1 /DEF=Homo sapiens hypothetical protein FLJ20283 (FLJ20283), mRNA. /FEA=mRNA /GEN=FLJ20283 /PROD=hypothetical protein FLJ20283 /DB_XREF=gi:8923261 /UG=Hs.44033 hypothetical protein FLJ20283 /FL=gb:NM_017743.1 NM_017743 dipeptidyl-peptidase 8 DPP8 54878 NM_017743 /// NM_130434 /// NM_197960 /// NM_197961 /// XM_005254500 /// XM_005254502 /// XM_005254505 /// XM_006720586 /// XM_006720587 0006508 // proteolysis // non-traceable author statement /// 0006955 // immune response // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 220940_at NM_025190 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025190.1 /DEF=Homo sapiens KIAA1641 protein (KIAA1641), mRNA. /FEA=mRNA /GEN=KIAA1641 /PROD=hypothetical protein FLJ21281 /DB_XREF=gi:13449272 /UG=Hs.44566 KIAA1641 protein /FL=gb:NM_025190.1 NM_025190 ankyrin repeat domain 36B ANKRD36B 57730 NM_020970 /// NM_025190 /// XM_005263995 /// XM_006712661 /// XM_006712662 /// XM_006712663 /// XM_006712664 /// XM_006712665 /// XM_006712666 /// XM_006712667 /// XM_006712668 /// XM_006712669 /// XM_006712670 /// XR_244894 220941_s_at NM_017447 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017447.1 /DEF=Homo sapiens hypothetical protein LOC54149 (YG81), mRNA. /FEA=mRNA /GEN=YG81 /PROD=hypothetical protein LOC54149 /DB_XREF=gi:8394546 /UG=Hs.49391 hypothetical protein LOC54149 /FL=gb:NM_017447.1 NM_017447 chromosome 21 open reading frame 91 C21orf91 54149 NM_001100420 /// NM_001100421 /// NM_017447 220942_x_at NM_014367 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014367.1 /DEF=Homo sapiens hypothetical protein, estradiol-induced (E2IG5), mRNA. /FEA=mRNA /GEN=E2IG5 /PROD=hypothetical protein, estradiol-induced /DB_XREF=gi:7657049 /UG=Hs.5243 hypothetical protein, estradiol-induced /FL=gb:AF191020.1 gb:NM_014367.1 NM_014367 family with sequence similarity 162, member A FAM162A 26355 NM_014367 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006927 // transformed cell apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 220943_s_at NM_018607 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018607.3 /DEF=Homo sapiens hypothetical protein PRO1853 (PRO1853), mRNA. /FEA=mRNA /GEN=PRO1853 /PROD=hypothetical protein PRO1853 /DB_XREF=gi:13699864 /UG=Hs.52891 hypothetical protein PRO1853 /FL=gb:NM_018607.3 NM_018607 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 NDUFAF7 55471 NM_001083946 /// NM_018607 /// NM_144736 /// XM_005264410 /// XM_005264411 0032259 // methylation // non-traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0008168 // methyltransferase activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 220944_at NM_020393 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020393.1 /DEF=Homo sapiens hypothetical protein SBBI67 (LOC57115), mRNA. /FEA=mRNA /GEN=LOC57115 /PROD=hypothetical protein SBBI67 /DB_XREF=gi:9966868 /UG=Hs.58356 hypothetical protein SBBI67 /FL=gb:AF242518.1 gb:NM_020393.1 NM_020393 peptidoglycan recognition protein 4 PGLYRP4 57115 NM_020393 /// XR_241090 0002221 // pattern recognition receptor signaling pathway // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0009253 // peptidoglycan catabolic process // inferred from electronic annotation /// 0016045 // detection of bacterium // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032827 // negative regulation of natural killer cell differentiation involved in immune response // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0044117 // growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // non-traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0016020 // membrane // non-traceable author statement 0008270 // zinc ion binding // inferred from electronic annotation /// 0008745 // N-acetylmuramoyl-L-alanine amidase activity // inferred from electronic annotation /// 0016019 // peptidoglycan receptor activity // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 220945_x_at NM_018050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018050.1 /DEF=Homo sapiens hypothetical protein FLJ10298 (FLJ10298), mRNA. /FEA=mRNA /GEN=FLJ10298 /PROD=hypothetical protein FLJ10298 /DB_XREF=gi:8922334 /UG=Hs.5999 hypothetical protein FLJ10298 /FL=gb:NM_018050.1 NM_018050 MANSC domain containing 1 MANSC1 54682 NM_018050 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220946_s_at NM_014159 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014159.1 /DEF=Homo sapiens HSPC069 protein (HSPC069), mRNA. /FEA=mRNA /GEN=HSPC069 /PROD=HSPC069 protein /DB_XREF=gi:7661773 /UG=Hs.6947 HSPC069 protein /FL=gb:AF161554.1 gb:NM_014159.1 NM_014159 SET domain containing 2 SETD2 29072 NM_012271 /// NM_014159 /// XM_005265094 /// XM_006713119 /// XM_006713120 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0010452 // histone H3-K36 methylation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018023 // peptidyl-lysine trimethylation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034728 // nucleosome organization // inferred from mutant phenotype /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035441 // cell migration involved in vasculogenesis // inferred from electronic annotation /// 0048332 // mesoderm morphogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048864 // stem cell development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060039 // pericardium development // inferred from electronic annotation /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0097198 // histone H3-K36 trimethylation // inferred from direct assay /// 0097198 // histone H3-K36 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046914 // transition metal ion binding // inferred from electronic annotation 220947_s_at NM_015527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015527.1 /DEF=Homo sapiens DKFZP434P1750 protein (DKFZP434P1750), mRNA. /FEA=mRNA /GEN=DKFZP434P1750 /PROD=DKFZP434P1750 protein /DB_XREF=gi:7661587 /UG=Hs.7274 DKFZP434P1750 protein /FL=gb:NM_015527.1 NM_015527 TBC1 domain family, member 10B TBC1D10B 26000 NM_015527 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay 220948_s_at NM_000701 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000701.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, alpha 1 polypeptide (ATP1A1), mRNA. /FEA=mRNA /GEN=ATP1A1 /PROD=ATPase, Na+K+ transporting, alpha 1polypeptide /DB_XREF=gi:4502268 /UG=Hs.76549 ATPase, Na+K+ transporting, alpha 1 polypeptide /FL=gb:NM_000701.1 gb:U16798.1 NM_000701 ATPase, Na+/K+ transporting, alpha 1 polypeptide ATP1A1 476 NM_000701 /// NM_001001586 /// NM_001160233 /// NM_001160234 /// XM_006710655 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0031947 // negative regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045823 // positive regulation of heart contraction // inferred from electronic annotation /// 0045989 // positive regulation of striated muscle contraction // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity 220949_s_at NM_024033 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024033.1 /DEF=Homo sapiens hypothetical protein MGC5242 (MGC5242), mRNA. /FEA=mRNA /GEN=MGC5242 /PROD=hypothetical protein MGC5242 /DB_XREF=gi:13162284 /UG=Hs.77365 hypothetical protein MGC5242 /FL=gb:BC000168.2 gb:NM_024033.1 NM_024033 chromosome 7 open reading frame 49 C7orf49 78996 NM_001243749 /// NM_001243751 /// NM_001243752 /// NM_001243753 /// NM_001243754 /// NM_001243755 /// NM_024033 0005737 // cytoplasm // inferred from electronic annotation 220950_s_at NM_017991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017991.1 /DEF=Homo sapiens hypothetical protein FLJ10081 (FLJ10081), mRNA. /FEA=mRNA /GEN=FLJ10081 /PROD=hypothetical protein FLJ10081 /DB_XREF=gi:8922221 /UG=Hs.7871 hypothetical protein FLJ10081 /FL=gb:NM_017991.1 NM_017991 KAT8 regulatory NSL complex subunit 3 KANSL3 55683 NM_001115016 /// NM_017991 /// NR_047653 /// NR_047654 /// NR_047655 /// NR_047656 /// NR_047657 /// NR_047658 /// XM_005263980 /// XM_005263981 /// XM_005263982 /// XM_005263983 /// XM_005263984 /// XM_005263985 /// XM_005263986 /// XM_005263987 /// XM_005263988 /// XM_005263992 /// XM_006712629 /// XM_006712630 /// XM_006712631 /// XR_244892 /// XR_427101 0006325 // chromatin organization // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 220951_s_at NM_014576 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014576.1 /DEF=Homo sapiens Apobec-1 complementation factor; APOBEC-1 stimulating protein (ACF), mRNA. /FEA=mRNA /GEN=ACF /PROD=Apobec-1 complementation factor; APOBEC-1stimulating protein /DB_XREF=gi:7656852 /UG=Hs.8349 Apobec-1 complementation factor; APOBEC-1 stimulating protein /FL=gb:AF209192.1 gb:NM_014576.1 gb:AF271789.1 NM_014576 APOBEC1 complementation factor A1CF 29974 NM_001198818 /// NM_001198819 /// NM_001198820 /// NM_014576 /// NM_138932 /// NM_138933 /// XM_005269718 /// XM_005269719 /// XM_005269720 /// XM_006717808 /// XM_006717809 0006397 // mRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016554 // cytidine to uridine editing // traceable author statement /// 0016556 // mRNA modification // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0030895 // apolipoprotein B mRNA editing enzyme complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 220952_s_at NM_019012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019012.1 /DEF=Homo sapiens hypothetical protein (FLJ10667), mRNA. /FEA=mRNA /GEN=FLJ10667 /PROD=hypothetical protein /DB_XREF=gi:9506616 /UG=Hs.86149 phosphoinositol 3-phosphate-binding protein-2 /FL=gb:NM_019012.1 NM_019012 pleckstrin homology domain containing, family A member 5 PLEKHA5 54477 NM_001143821 /// NM_001190860 /// NM_001256470 /// NM_001256787 /// NM_019012 /// XM_005253398 /// XM_005253399 /// XM_005253400 /// XM_006719089 /// XM_006719090 /// XM_006719091 /// XM_006719092 /// XM_006719093 /// XM_006719094 /// XM_006719095 /// XM_006719096 /// XR_429037 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // non-traceable author statement 220953_s_at NM_019061 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019061.1 /DEF=Homo sapiens hypothetical protein (FLJ20476), mRNA. /FEA=mRNA /GEN=FLJ20476 /PROD=hypothetical protein /DB_XREF=gi:9506678 /UG=Hs.93872 KIAA1682 protein /FL=gb:NM_019061.1 NM_019061 myotubularin related protein 12 MTMR12 54545 NM_001040446 /// NM_001294343 /// NM_001294344 /// NM_019061 /// XM_005248313 /// XM_005248314 /// XM_005248316 /// XM_005248317 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from electronic annotation 220954_s_at NM_013440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013440.1 /DEF=Homo sapiens paired immunoglobulin-like receptor beta (PILR(BETA)), mRNA. /FEA=mRNA /GEN=PILR(BETA) /PROD=paired immunoglobulin-like receptor beta /DB_XREF=gi:7305386 /UG=Hs.9408 paired immunoglobulin-like receptor beta /FL=gb:AF161081.1 gb:NM_013440.1 NM_013440 microRNA 6840 /// paired immunoglobin-like type 2 receptor beta /// STAG3L5P-PVRIG2P-PILRB readthrough MIR6840 /// PILRB /// STAG3L5P-PVRIG2P-PILRB 29990 /// 101752399 /// 102466747 NM_013440 /// NM_175047 /// NM_178238 /// NR_036569 /// NR_036570 /// NR_106899 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // non-traceable author statement 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220955_x_at NM_016277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016277.1 /DEF=Homo sapiens RAB23, member RAS oncogene family (RAB23), mRNA. /FEA=mRNA /GEN=RAB23 /PROD=RAB23 protein /DB_XREF=gi:7706472 /UG=Hs.94769 RAB23, member RAS oncogene family /FL=gb:AB034244.1 gb:NM_016277.1 NM_016277 RAB23, member RAS oncogene family RAB23 51715 NM_001278666 /// NM_001278667 /// NM_001278668 /// NM_016277 /// NM_183227 /// NR_103822 /// XM_005249179 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006968 // cellular defense response // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0021513 // spinal cord dorsal/ventral patterning // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0097094 // craniofacial suture morphogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation 220956_s_at NM_017555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017555.1 /DEF=Homo sapiens hypothetical protein DKFZp434E026 (DKFZp434E026), mRNA. /FEA=mRNA /GEN=DKFZp434E026 /PROD=hypothetical protein DKFZp434E026 /DB_XREF=gi:8922129 /UG=Hs.9659 hypothetical protein DKFZp434E026 /FL=gb:NM_017555.1 NM_017555 egl-9 family hypoxia-inducible factor 2 /// RAB4B-EGLN2 readthrough (NMD candidate) EGLN2 /// RAB4B-EGLN2 112398 /// 100529264 NM_017555 /// NM_053046 /// NM_080732 /// NR_037791 0001558 // regulation of cell growth // non-traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0046323 // glucose import // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032593 // insulin-responsive compartment // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from direct assay /// 0019826 // oxygen sensor activity // inferred from direct assay /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0031543 // peptidyl-proline dioxygenase activity // inferred from electronic annotation /// 0031545 // peptidyl-proline 4-dioxygenase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 220957_at NM_022663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022663.1 /DEF=Homo sapiens CTAGE-1 protein (CTAGE-1), mRNA. /FEA=mRNA /GEN=CTAGE-1 /PROD=CTAGE-1 protein /DB_XREF=gi:12056974 /UG=Hs.97672 CTAGE-1 protein /FL=gb:AF177229.1 gb:NM_022663.1 NM_022663 cutaneous T-cell lymphoma-associated antigen 1 CTAGE1 64693 NM_022663 /// NM_172241 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220958_at NM_017886 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017886.1 /DEF=Homo sapiens hypothetical protein FLJ20574 (FLJ20574), mRNA. /FEA=mRNA /GEN=FLJ20574 /PROD=hypothetical protein FLJ20574 /DB_XREF=gi:8923538 /UG=Hs.99514 hypothetical protein FLJ20574 /FL=gb:NM_017886.1 NM_017886 unc-51 like kinase 4 ULK4 54986 NM_017886 /// XM_005265261 /// XM_005265262 /// XM_006713215 /// XR_427279 0003351 // epithelial cilium movement // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 220959_s_at NM_014581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014581.1 /DEF=Homo sapiens odorant-binding protein 2B (OBP2B), mRNA. /FEA=mRNA /GEN=OBP2B /PROD=odorant-binding protein 2B /DB_XREF=gi:7657406 /UG=Hs.99526 odorant-binding protein 2B /FL=gb:NM_014581.1 NM_014581 odorant binding protein 2A /// odorant binding protein 2B OBP2A /// OBP2B 29989 /// 29991 NM_001288987 /// NM_001293189 /// NM_001293193 /// NM_014581 /// NM_014582 /// NR_110242 /// NR_110243 /// NR_120603 /// XM_006717086 /// XM_006717087 0006810 // transport // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0007608 // sensory perception of smell // non-traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007635 // chemosensory behavior // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005549 // odorant binding // non-traceable author statement 220960_x_at NM_000983 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000983.1 /DEF=Homo sapiens ribosomal protein L22 (RPL22), mRNA. /FEA=mRNA /GEN=RPL22 /PROD=ribosomal protein L22 /DB_XREF=gi:4506612 /UG=Hs.99914 ribosomal protein L22 /FL=gb:NM_000983.1 NM_000983 ribosomal protein L22 RPL22 6146 NM_000983 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220961_s_at NM_030900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030900.1 /DEF=Homo sapiens KIAA0948 protein (KIAA0948), mRNA. /FEA=mRNA /GEN=KIAA0948 /PROD=KIAA0948 protein /DB_XREF=gi:13569847 /FL=gb:NM_030900.1 NM_030900 transforming growth factor beta regulator 4 TBRG4 9238 NM_001261834 /// NM_004749 /// NM_030900 /// NM_199122 0000080 // mitotic G1 phase // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0045333 // cellular respiration // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 220962_s_at NM_013358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013358.1 /DEF=Homo sapiens peptidylarginine deiminase type I (hPAD-colony10), mRNA. /FEA=mRNA /GEN=hPAD-colony10 /PROD=peptidylarginine deiminase type I /DB_XREF=gi:13591857 /FL=gb:NM_013358.1 NM_013358 peptidyl arginine deiminase, type I PADI1 29943 NM_013358 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018101 // protein citrullination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004668 // protein-arginine deiminase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 220963_s_at NM_030907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030907.1 /DEF=Homo sapiens hypothetical protein MGC10731 (MGC10731), mRNA. /FEA=mRNA /GEN=MGC10731 /PROD=hypothetical protein MGC10731 /DB_XREF=gi:13569861 /FL=gb:NM_030907.1 NM_030907 REM2 and RAB-like small GTPase 1 RSG1 79363 NM_030907 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031338 // regulation of vesicle fusion // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 220964_s_at NM_030981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030981.1 /DEF=Homo sapiens small GTP-binding protein (RAB1B), mRNA. /FEA=mRNA /GEN=RAB1B /PROD=small GTP-binding protein /DB_XREF=gi:13569961 /FL=gb:NM_030981.1 NM_030981 RAB1B, member RAS oncogene family RAB1B 81876 NM_030981 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 220965_s_at NM_030785 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030785.1 /DEF=Homo sapiens ortholog of mouse radial spokehead-like 1 (RSHL1), mRNA. /FEA=mRNA /GEN=RSHL1 /PROD=ortholog of mouse radial spokehead-like 1 /DB_XREF=gi:13540558 /FL=gb:NM_030785.1 NM_030785 radial spoke head 6 homolog A (Chlamydomonas) RSPH6A 81492 NM_030785 0005622 // intracellular // inferred from direct assay 220966_x_at NM_030978 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030978.1 /DEF=Homo sapiens hypothetical protein similar to actin related protein 23 complex, subunit 5 (MGC3038), mRNA. /FEA=mRNA /GEN=MGC3038 /PROD=hypothetical protein similar to actin relatedprotein 23 complex, subunit 5 /DB_XREF=gi:13569955 /FL=gb:NM_030978.1 NM_030978 actin related protein 2/3 complex, subunit 5-like ARPC5L 81873 NM_030978 /// XM_005252250 0030833 // regulation of actin filament polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 220967_s_at NM_030895 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030895.1 /DEF=Homo sapiens hypothetical protein FLJ14129 (FLJ14129), mRNA. /FEA=mRNA /GEN=FLJ14129 /PROD=hypothetical protein FLJ14129 /DB_XREF=gi:13569857 /FL=gb:NM_030895.1 NM_030895 zinc finger protein 696 ZNF696 79943 NM_030895 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 220968_s_at NM_031285 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031285.1 /DEF=Homo sapiens hypothetical protein PP1057 (PP1057), mRNA. /FEA=mRNA /GEN=PP1057 /PROD=hypothetical protein PP1057 /DB_XREF=gi:13775195 /FL=gb:NM_031285.1 NM_031285 tetraspanin 9 TSPAN9 10867 NM_001168320 /// NM_006675 /// XM_006718956 /// XM_006718957 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 220969_s_at NM_030892 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030892.1 /DEF=Homo sapiens hypothetical protein FLJ11786 (FLJ11786), mRNA. /FEA=mRNA /GEN=FLJ11786 /PROD=hypothetical protein FLJ11786 /DB_XREF=gi:13569855 /FL=gb:NM_030892.1 NM_030892 220970_s_at NM_030977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030977.1 /DEF=Homo sapiens keratin associated protein KRTAP2.1A (KRTAP2.1A), mRNA. /FEA=mRNA /GEN=KRTAP2.1A /PROD=keratin associated protein KRTAP2.1A /DB_XREF=gi:13569953 /FL=gb:NM_030977.1 NM_030977 keratin associated protein 2-3 /// keratin associated protein 2-4 KRTAP2-3 /// KRTAP2-4 85294 /// 730755 NM_001165252 /// NM_033184 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 220971_at NM_022789 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022789.1 /DEF=Homo sapiens interleukin 17E (IL17E), mRNA. /FEA=mRNA /GEN=IL17E /PROD=interleukin 17E /DB_XREF=gi:12232484 /UG=Hs.302036 interleukin 17E /FL=gb:AF305200.1 gb:NM_022789.1 NM_022789 interleukin 25 IL25 64806 NM_022789 /// NM_172314 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0009624 // response to nematode // inferred from electronic annotation /// 0030222 // eosinophil differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0030380 // interleukin-17E receptor binding // traceable author statement 220972_s_at NM_030975 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030975.1 /DEF=Homo sapiens keratin associated protein 9.9 (KRTAP9.9), mRNA. /FEA=mRNA /GEN=KRTAP9.9 /PROD=keratin associated protein 9.9 /DB_XREF=gi:13569951 /FL=gb:NM_030975.1 NM_030975 keratin associated protein 9-9 KRTAP9-9 81870 NM_030975 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 220973_s_at NM_030974 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030974.1 /DEF=Homo sapiens hypothetical protein DKFZp434N1923 (DKFZP434N1923), mRNA. /FEA=mRNA /GEN=DKFZP434N1923 /PROD=hypothetical protein DKFZp434N1923 /DB_XREF=gi:13569949 /FL=gb:NM_030974.1 NM_030974 SHANK-associated RH domain interactor SHARPIN 81858 NM_030974 /// NR_038270 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0010803 // regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0030262 // apoptotic nuclear changes // inferred from electronic annotation /// 0031424 // keratinization // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0097039 // protein linear polyubiquitination // inferred from direct assay /// 2000348 // regulation of CD40 signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071797 // LUBAC complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220974_x_at NM_030971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030971.1 /DEF=Homo sapiens similar to rat tricarboxylate carrier-like protein (BA108L7.2), mRNA. /FEA=mRNA /GEN=BA108L7.2 /PROD=similar to rat tricarboxylate carrier-likeprotein /DB_XREF=gi:13569945 /FL=gb:NM_030971.1 NM_030971 sideroflexin 3 SFXN3 81855 NM_030971 /// XR_428720 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0008324 // cation transmembrane transporter activity // inferred from electronic annotation 220975_s_at NM_030968 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030968.1 /DEF=Homo sapiens G protein coupled receptor interacting protein, complement-c1q tumor necrosis factor-related (ZSIG37), mRNA. /FEA=mRNA /GEN=ZSIG37 /PROD=G protein coupled receptor interacting protein,complement-c1q tumor necrosis factor-related /DB_XREF=gi:13569943 /FL=gb:NM_030968.1 NM_030968 C1q and tumor necrosis factor related protein 1 C1QTNF1 114897 NM_030968 /// NM_153372 /// NM_198593 /// NM_198594 /// NR_049769 /// XM_006721663 /// XM_006721664 /// XM_006721665 /// XM_006721666 /// XM_006721667 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0090331 // negative regulation of platelet aggregation // inferred from direct assay /// 2000860 // positive regulation of aldosterone secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay 220976_s_at NM_030967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030967.1 /DEF=Homo sapiens keratin associated protein 1.1 (KRTAP1.1), mRNA. /FEA=mRNA /GEN=KRTAP1.1 /PROD=keratin associated protein 1.1 /DB_XREF=gi:13569941 /FL=gb:NM_030967.1 NM_030967 keratin associated protein 1-1 KRTAP1-1 81851 NM_030967 0005576 // extracellular region // non-traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 220977_x_at NM_020909 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020909.1 /DEF=Homo sapiens KIAA1548 protein (KIAA1548), mRNA. /FEA=mRNA /GEN=KIAA1548 /PROD=KIAA1548 protein /DB_XREF=gi:13540487 /FL=gb:NM_020909.1 NM_020909 erythrocyte membrane protein band 4.1 like 5 EPB41L5 57669 NM_001184937 /// NM_001184938 /// NM_001184939 /// NM_020909 /// XM_005263719 /// XM_005263720 /// XM_006712651 /// XM_006712652 /// XM_006712653 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001839 // neural plate morphogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0003383 // apical constriction // inferred from electronic annotation /// 0006931 // substrate-dependent cell migration, cell attachment to substrate // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0007509 // mesoderm migration involved in gastrulation // inferred from electronic annotation /// 0009826 // unidimensional cell growth // inferred from electronic annotation /// 0010608 // posttranscriptional regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048318 // axial mesoderm development // inferred from electronic annotation /// 0048319 // axial mesoderm morphogenesis // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0070201 // regulation of establishment of protein localization // inferred from electronic annotation /// 0070986 // left/right axis specification // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 220978_at NM_030966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030966.1 /DEF=Homo sapiens keratin associated protein 1.3 (KRTAP1.3), mRNA. /FEA=mRNA /GEN=KRTAP1.3 /PROD=keratin associated protein 1.3 /DB_XREF=gi:13569939 /FL=gb:NM_030966.1 NM_030966 keratin associated protein 1-3 KRTAP1-3 81850 NM_030966 0005576 // extracellular region // non-traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0045095 // keratin filament // inferred from electronic annotation 0030280 // structural constituent of epidermis // non-traceable author statement 220979_s_at NM_030965 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030965.1 /DEF=Homo sapiens similar to sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E (MGC3184), mRNA. /FEA=mRNA /GEN=MGC3184 /PROD=similar to sialyltransferase 7((alpha-N-acetylneuraminyl2,3-betagalactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) E /DB_XREF=gi:13569937 /FL=gb:NM_030965.1 NM_030965 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6GALNAC5 81849 NM_030965 /// XM_005271238 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from sequence or structural similarity /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0001665 // alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity // inferred from sequence or structural similarity /// 0008373 // sialyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 220980_s_at NM_031284 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031284.1 /DEF=Homo sapiens hypothetical protein DKFZp434B195 (DKFZP434B195), mRNA. /FEA=mRNA /GEN=DKFZP434B195 /PROD=hypothetical protein DKFZp434B195 /DB_XREF=gi:13775193 /FL=gb:NM_031284.1 NM_031284 ADP-dependent glucokinase ADPGK 83440 NM_031284 /// NR_023318 /// NR_023319 /// XM_006720712 /// XM_006720713 /// XM_006720714 /// XM_006720715 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0043843 // ADP-specific glucokinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220981_x_at NM_022053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022053.1 /DEF=Homo sapiens nuclear RNA export factor 2 (NXF2), mRNA. /FEA=mRNA /GEN=NXF2 /PROD=nuclear RNA export factor 2 /DB_XREF=gi:13430853 /UG=Hs.306209 nuclear RNA export factor 2 /FL=gb:NM_022053.1 NM_022053 nuclear RNA export factor 2 /// nuclear RNA export factor 2B NXF2 /// NXF2B 56001 /// 728343 NM_001039910 /// NM_001099686 /// NM_017809 /// NM_022053 /// XM_006710259 0006406 // mRNA export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from sequence or structural similarity /// 0050658 // RNA transport // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 220982_s_at NM_030960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030960.1 /DEF=Homo sapiens sperm acrosome associated 1 (SPACA1), mRNA. /FEA=mRNA /GEN=SPACA1 /PROD=sperm acrosome associated 1 /DB_XREF=gi:13569933 /FL=gb:NM_030960.1 NM_030960 sperm acrosome associated 1 SPACA1 81833 NM_030960 /// XR_241854 0001675 // acrosome assembly // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation 0002080 // acrosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220983_s_at NM_030964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030964.1 /DEF=Homo sapiens sprouty (Drosophila) homolog 4 (SPRY4), mRNA. /FEA=mRNA /GEN=SPRY4 /PROD=sprouty (Drosophila) homolog 4 /DB_XREF=gi:13569935 /FL=gb:NM_030964.1 NM_030964 microRNA 612 /// nuclear paraspeckle assembly transcript 1 (non-protein coding) MIR612 /// NEAT1 283131 /// 693197 NR_002802 /// NR_028272 /// NR_030343 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220984_s_at NM_030958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030958.1 /DEF=Homo sapiens organic anion transporter polypeptide-related protein 4 (OATPRP4), mRNA. /FEA=mRNA /GEN=OATPRP4 /PROD=organic anion transporter polypeptide-relatedprotein 4 /DB_XREF=gi:13569931 /FL=gb:NM_030958.1 NM_030958 solute carrier organic anion transporter family, member 5A1 SLCO5A1 81796 NM_001146008 /// NM_001146009 /// NM_030958 /// XM_005251313 /// XR_428341 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 220985_s_at NM_030954 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030954.1 /DEF=Homo sapiens hypothetical protein DKFZp564A022 (DKFZP564A022), mRNA. /FEA=mRNA /GEN=DKFZP564A022 /PROD=hypothetical protein DKFZp564A022 /DB_XREF=gi:13569925 /FL=gb:NM_030954.1 NM_030954 ring finger protein 170 RNF170 81790 NM_001160223 /// NM_001160224 /// NM_001160225 /// NM_030954 /// NR_027668 /// NR_027669 /// XM_006716404 /// XM_006716405 /// XM_006716406 /// XM_006716407 0016567 // protein ubiquitination // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220986_s_at NM_030953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030953.1 /DEF=Homo sapiens hypothetical protein DKFZp761E2110 (DKFZP761E2110), mRNA. /FEA=mRNA /GEN=DKFZP761E2110 /PROD=hypothetical protein DKFZp761E2110 /DB_XREF=gi:13569923 /FL=gb:NM_030953.1 NM_030953 tigger transposable element derived 6 TIGD6 81789 NM_001243253 /// NM_030953 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation 220987_s_at NM_030952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030952.1 /DEF=Homo sapiens hypothetical protein DKFZp434J037 (DKFZP434J037), mRNA. /FEA=mRNA /GEN=DKFZP434J037 /PROD=hypothetical protein DKFZp434J037 /DB_XREF=gi:13569921 /FL=gb:NM_030952.1 NM_030952 A kinase (PRKA) interacting protein 1 /// NUAK family, SNF1-like kinase, 2 AKIP1 /// NUAK2 56672 /// 81788 NM_001206645 /// NM_001206646 /// NM_001206647 /// NM_001206648 /// NM_020642 /// NM_030952 /// NM_182901 /// NR_045417 /// NR_045418 /// XM_005245515 /// XM_006718264 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220988_s_at NM_030945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030945.1 /DEF=Homo sapiens complement-c1q tumor necrosis factor-related protein; likely ortholog of mouse CORS26 (collagenous repeat-containing sequence of 26-kDa protein) (CTRP3), mRNA. /FEA=mRNA /GEN=CTRP3 /PROD=complement-c1q tumor necrosis factor-relatedprotein; likely ortholog of mouse CORS26 (collagenousrepeat-containing sequence of 26-kDa protein) /DB_XREF=gi:13569918 /FL=gb:NM_030945.1 NM_030945 C1q and tumor necrosis factor related protein 3 C1QTNF3 114899 NM_030945 /// NM_181435 0010629 // negative regulation of gene expression // inferred from direct assay /// 0035356 // cellular triglyceride homeostasis // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from expression pattern /// 0045721 // negative regulation of gluconeogenesis // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0070165 // positive regulation of adiponectin secretion // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 220989_s_at NM_030943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030943.1 /DEF=Homo sapiens amnionless protein (AMN), mRNA. /FEA=mRNA /GEN=AMN /PROD=amnionless protein /DB_XREF=gi:13569914 /FL=gb:NM_030943.1 NM_030943 amnion associated transmembrane protein AMN 81693 NM_030943 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007010 // cytoskeleton organization // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0042641 // actomyosin // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220990_s_at NM_030938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030938.1 /DEF=Homo sapiens hypothetical protein DKFZp566I133 (DKFZP566I133), mRNA. /FEA=mRNA /GEN=DKFZP566I133 /PROD=hypothetical protein DKFZp566I133 /DB_XREF=gi:13569906 /FL=gb:NM_030938.1 NM_030938 microRNA 21 /// vacuole membrane protein 1 MIR21 /// VMP1 81671 /// 406991 NM_030938 /// NR_029493 0006914 // autophagy // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0034329 // cell junction assembly // inferred from mutant phenotype 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from sequence or structural similarity /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 220991_s_at NM_030936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030936.1 /DEF=Homo sapiens hypothetical protein DKFZp434C135 (DKFZP434C135), mRNA. /FEA=mRNA /GEN=DKFZP434C135 /PROD=hypothetical protein DKFZp434C135 /DB_XREF=gi:13569902 /FL=gb:NM_030936.1 NM_030936 ring finger protein 32 RNF32 140545 NM_001184996 /// NM_001184997 /// NM_030936 /// XM_005249522 /// XM_006715851 /// XM_006715852 /// XR_428167 /// XR_428168 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 220992_s_at NM_030934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030934.1 /DEF=Homo sapiens novel protein similar to archaeal, yeast and worm N2,N2-dimethylguanosine tRNA methyltransferase (C1ORF25), mRNA. /FEA=mRNA /GEN=C1ORF25 /PROD=novel protein similar to archaeal, yeast andworm N2,N2-dimethylguanosine tRNA methyltransferase /DB_XREF=gi:13569898 /FL=gb:NM_030934.1 NM_030934 tRNA methyltransferase 1 homolog (S. cerevisiae)-like TRMT1L 81627 NM_001202423 /// NM_030934 0007610 // behavior // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0030534 // adult behavior // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004809 // tRNA (guanine-N2-)-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 220993_s_at NM_030784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030784.1 /DEF=Homo sapiens brain expressed G-protein-coupled receptor PSP24 beta (PSP24B), mRNA. /FEA=mRNA /GEN=PSP24B /PROD=brain expressed G-protein-coupled receptor PSP24beta /DB_XREF=gi:13540556 /FL=gb:NM_030784.1 NM_030784 G protein-coupled receptor 63 GPR63 81491 NM_001143957 /// NM_030784 /// XM_006715569 /// XM_006715570 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 220994_s_at NM_014178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014178.1 /DEF=Homo sapiens HSPC156 protein (HSPC156), mRNA. /FEA=mRNA /GEN=HSPC156 /PROD=HSPC156 protein /DB_XREF=gi:7661811 /UG=Hs.99291 HSPC156 protein /FL=gb:AF161505.1 gb:NM_014178.1 NM_014178 syntaxin binding protein 6 (amisyn) STXBP6 29091 NM_014178 /// XM_005267556 /// XM_006720121 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220995_at NM_014178 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014178.1 /DEF=Homo sapiens HSPC156 protein (HSPC156), mRNA. /FEA=mRNA /GEN=HSPC156 /PROD=HSPC156 protein /DB_XREF=gi:7661811 /UG=Hs.99291 HSPC156 protein /FL=gb:AF161505.1 gb:NM_014178.1 NM_014178 syntaxin binding protein 6 (amisyn) STXBP6 29091 NM_014178 /// XM_005267556 /// XM_006720121 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 220996_s_at NM_030933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030933.1 /DEF=Homo sapiens GE36 gene (GE36), mRNA. /FEA=mRNA /GEN=GE36 /PROD=GE36 gene /DB_XREF=gi:13569896 /FL=gb:NM_030933.1 NM_030933 SHC SH2-domain binding protein 1-like SHCBP1L 81626 NM_030933 220997_s_at NM_030932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030932.1 /DEF=Homo sapiens diaphanous (Drosophila, homolog) 3 (DKFZP434C0931), mRNA. /FEA=mRNA /GEN=DKFZP434C0931 /PROD=diaphanous (Drosophila, homolog) 3 /DB_XREF=gi:13569894 /FL=gb:NM_030932.1 NM_030932 diaphanous-related formin 3 DIAPH3 81624 NM_001042517 /// NM_001258366 /// NM_001258367 /// NM_001258368 /// NM_001258369 /// NM_001258370 /// NM_030932 /// XM_006719876 0007283 // spermatogenesis // inferred from electronic annotation /// 0016043 // cellular component organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation 220998_s_at NM_030930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030930.1 /DEF=Homo sapiens unc93 (C.elegans) homolog B (UNC93B), mRNA. /FEA=mRNA /GEN=UNC93B /PROD=unc93 (C.elegans) homolog B /DB_XREF=gi:13569892 /FL=gb:NM_030930.1 NM_030930 unc-93 homolog B1 (C. elegans) UNC93B1 81622 NM_030930 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // inferred from mutant phenotype /// 0034154 // toll-like receptor 7 signaling pathway // inferred from mutant phenotype /// 0034162 // toll-like receptor 9 signaling pathway // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032009 // early phagosome // inferred from sequence or structural similarity /// 0045335 // phagocytic vesicle // inferred from electronic annotation 220999_s_at NM_030778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030778.1 /DEF=Homo sapiens hypothetical protein PRO1331 (PRO1331), mRNA. /FEA=mRNA /GEN=PRO1331 /PROD=hypothetical protein PRO1331 /DB_XREF=gi:13562115 /FL=gb:NM_030778.1 NM_030778 cytoplasmic FMR1 interacting protein 2 CYFIP2 26999 NM_001037332 /// NM_001037333 /// NM_001291721 /// NM_001291722 /// NM_014376 0006915 // apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221000_s_at NM_030929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030929.1 /DEF=Homo sapiens hypothetical protein FKSG28 (FKSG28), mRNA. /FEA=mRNA /GEN=FKSG28 /PROD=hypothetical protein FKSG28 /DB_XREF=gi:13569890 /FL=gb:NM_030929.1 NM_030929 Kazal-type serine peptidase inhibitor domain 1 KAZALD1 81621 NM_030929 /// XM_005270193 /// XM_005270194 /// XR_246107 0001503 // ossification // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005520 // insulin-like growth factor binding // inferred from electronic annotation 221001_at NM_030879 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030879.1 /DEF=Homo sapiens Small evolutionarily conserved RNA, resembling CD box small nucleolar (X102), mRNA. /FEA=mRNA /GEN=X102 /PROD=Small evolutionarily conserved RNA, resemblingCD box small nucleolar /DB_XREF=gi:13562105 /FL=gb:NM_030879.1 NM_030879 Homo sapiens chromosome 15 open reading frame 49, mRNA (cDNA clone MGC:95352 IMAGE:7216891), complete cds. C15orf49 221002_s_at NM_030927 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030927.1 /DEF=Homo sapiens hypothetical protein MGC11352 (MGC11352), mRNA. /FEA=mRNA /GEN=MGC11352 /PROD=hypothetical protein MGC11352 /DB_XREF=gi:13569888 /FL=gb:NM_030927.1 NM_030927 tetraspanin 14 TSPAN14 81619 NM_001128309 /// NM_030927 /// XM_005270191 /// XM_005270192 /// XM_006717990 /// XM_006717991 /// XM_006717992 0045747 // positive regulation of Notch signaling pathway // inferred from mutant phenotype /// 0051604 // protein maturation // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction 221003_s_at NM_030925 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030925.1 /DEF=Homo sapiens hypothetical protein FLJ12577 (FLJ12577), mRNA. /FEA=mRNA /GEN=FLJ12577 /PROD=hypothetical protein FLJ12577 /DB_XREF=gi:13569886 /FL=gb:NM_030925.1 NM_030925 calcium binding protein 39-like CAB39L 81617 NM_001079670 /// NM_001287337 /// NM_001287338 /// NM_001287339 /// NM_030925 0007050 // cell cycle arrest // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation 221004_s_at NM_030926 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030926.1 /DEF=Homo sapiens integral membrane protein 3 (ITM3), mRNA. /FEA=mRNA /GEN=ITM3 /PROD=integral membrane protein 3 /DB_XREF=gi:13569884 /FL=gb:NM_030926.1 NM_030926 integral membrane protein 2C ITM2C 81618 NM_001012514 /// NM_001012516 /// NM_001287240 /// NM_001287241 /// NM_030926 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030182 // neuron differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 221005_s_at NM_030783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030783.1 /DEF=Homo sapiens phosphatidylserine synthase 2 (PTDSS2), mRNA. /FEA=mRNA /GEN=PTDSS2 /PROD=phosphatidylserine synthase 2 /DB_XREF=gi:13540554 /FL=gb:NM_030783.1 NM_030783 phosphatidylserine synthase 2 PTDSS2 81490 NM_030783 /// XM_005253153 /// XR_242827 /// XR_242828 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006659 // phosphatidylserine biosynthetic process // inferred from electronic annotation /// 0006659 // phosphatidylserine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation 0003882 // CDP-diacylglycerol-serine O-phosphatidyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221006_s_at NM_030918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030918.1 /DEF=Homo sapiens hypothetical protein My014 (MY014), mRNA. /FEA=mRNA /GEN=MY014 /PROD=hypothetical protein My014 /DB_XREF=gi:13569876 /FL=gb:NM_030918.1 NM_030918 sorting nexin family member 27 SNX27 81609 NM_030918 /// XM_005245509 /// XM_005245510 /// XM_005245511 /// XM_005245512 0001770 // establishment of natural killer cell polarity // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 221007_s_at NM_030917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030917.1 /DEF=Homo sapiens hypothetical protein DKFZp586K0717 (DKFZP586K0717), mRNA. /FEA=mRNA /GEN=DKFZP586K0717 /PROD=hypothetical protein DKFZp586K0717 /DB_XREF=gi:13569873 /FL=gb:NM_030917.1 NM_030917 factor interacting with PAPOLA and CPSF1 FIP1L1 81608 NM_001134937 /// NM_001134938 /// NM_030917 /// XM_005265768 /// XM_005265769 /// XM_005265770 /// XM_005265771 /// XM_005265772 /// XM_005265773 /// XM_005265774 /// XM_005265775 /// XM_005265776 /// XM_005265777 /// XM_005265778 /// XM_005265779 /// XM_005265780 /// XM_005265781 /// XM_005265782 0006397 // mRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221008_s_at NM_031279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031279.1 /DEF=Homo sapiens alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), mRNA. /FEA=mRNA /GEN=AGXT2L1 /PROD=alanine-glyoxylate aminotransferase 2-like 1 /DB_XREF=gi:13775189 /FL=gb:NM_031279.1 NM_031279 ethanolamine-phosphate phospho-lyase ETNPPL 64850 NM_001146590 /// NM_001146627 /// NM_031279 /// NR_027474 /// NR_027475 /// XM_006714290 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008453 // alanine-glyoxylate transaminase activity // non-traceable author statement /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0050459 // ethanolamine-phosphate phospho-lyase activity // inferred from electronic annotation 221009_s_at NM_016109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016109.1 /DEF=Homo sapiens PPAR(gamma) angiopoietin related protein (PGAR), mRNA. /FEA=mRNA /GEN=PGAR /PROD=PPAR(gamma) angiopoietin related protein /DB_XREF=gi:7705828 /UG=Hs.9613 PPAR(gamma) angiopoietin related protein /FL=gb:AF153606.1 gb:NM_016109.1 NM_016109 angiopoietin-like 4 ANGPTL4 51129 NM_001039667 /// NM_016109 /// NM_139314 /// NR_104213 /// XM_005272484 /// XM_005272485 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // traceable author statement /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 221010_s_at NM_031244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031244.1 /DEF=Homo sapiens sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5 (SIRT5), transcript variant 2, mRNA. /FEA=mRNA /GEN=SIRT5 /PROD=sirtuin 5, isoform 2 /DB_XREF=gi:13787214 /FL=gb:NM_031244.1 NM_031244 sirtuin 5 SIRT5 23408 NM_001193267 /// NM_001242827 /// NM_012241 /// NM_031244 /// XM_005248967 /// XM_005248968 /// XM_005248969 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0036047 // peptidyl-lysine demalonylation // inferred from direct assay /// 0036048 // protein desuccinylation // inferred from direct assay /// 0036049 // peptidyl-lysine desuccinylation // inferred from direct assay /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036054 // protein-malonyllysine demalonylase activity // inferred from direct assay /// 0036055 // protein-succinyllysine desuccinylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 221011_s_at NM_030915 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030915.1 /DEF=Homo sapiens hypothetical protein DKFZp566J091 (DKFZP566J091), mRNA. /FEA=mRNA /GEN=DKFZP566J091 /PROD=hypothetical protein DKFZp566J091 /DB_XREF=gi:13569871 /FL=gb:NM_030915.1 NM_030915 limb bud and heart development LBH 81606 NM_030915 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 221012_s_at NM_030912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030912.1 /DEF=Homo sapiens tripartite motif protein TRIM8 (TRIM8), mRNA. /FEA=mRNA /GEN=TRIM8 /PROD=tripartite motif protein TRIM8 /DB_XREF=gi:13569865 /FL=gb:NM_030912.1 NM_030912 tripartite motif containing 8 TRIM8 81603 NM_030912 /// XM_006717988 /// XM_006717989 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221013_s_at NM_030882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030882.1 /DEF=Homo sapiens apolipoprotein L, 2 (APOL2), mRNA. /FEA=mRNA /GEN=APOL2 /PROD=apolipoprotein L, 2 /DB_XREF=gi:13562089 /FL=gb:NM_030882.1 NM_030882 apolipoprotein L, 2 APOL2 23780 NM_030882 /// NM_145637 /// XM_006724217 /// XM_006724218 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // non-traceable author statement /// 0006953 // acute-phase response // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005102 // receptor binding // non-traceable author statement /// 0008035 // high-density lipoprotein particle binding // non-traceable author statement /// 0008289 // lipid binding // non-traceable author statement 221014_s_at NM_031296 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031296.1 /DEF=Homo sapiens hypothetical protein DKFZp434G099 (DKFZP434G099), mRNA. /FEA=mRNA /GEN=DKFZP434G099 /PROD=hypothetical protein DKFZp434G099 /DB_XREF=gi:13786128 /FL=gb:NM_031296.1 NM_031296 RAB33B, member RAS oncogene family RAB33B 83452 NM_031296 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 2000156 // regulation of retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 2000785 // regulation of autophagic vacuole assembly // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 221015_s_at NM_030911 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030911.1 /DEF=Homo sapiens protein kinase NYD-SP15 (NYD-SP15), mRNA. /FEA=mRNA /GEN=NYD-SP15 /PROD=protein kinase NYD-SP15 /DB_XREF=gi:13569863 /FL=gb:NM_030911.1 NM_030911 cytidine and dCMP deaminase domain containing 1 CDADC1 81602 NM_001193478 /// NM_030911 /// NR_036439 /// XM_006719871 /// XM_006719872 /// XM_006719873 /// XM_006719874 /// XM_006719875 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221016_s_at NM_031283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031283.1 /DEF=Homo sapiens HMG-box transcription factor TCF-3 (TCF-3), mRNA. /FEA=mRNA /GEN=TCF-3 /PROD=HMG-box transcription factor TCF-3 /DB_XREF=gi:13786122 /FL=gb:NM_031283.1 NM_031283 transcription factor 7-like 1 (T-cell specific, HMG-box) TCF7L1 83439 NM_031283 /// XM_006712109 /// XM_006712110 0006325 // chromatin organization // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0007420 // brain development // not recorded /// 0008595 // anterior/posterior axis specification, embryo // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030111 // regulation of Wnt signaling pathway // non-traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046022 // positive regulation of transcription from RNA polymerase II promoter during mitosis // inferred from electronic annotation /// 0048319 // axial mesoderm morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // not recorded /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // not recorded /// 2000036 // regulation of stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // not recorded 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008013 // beta-catenin binding // not recorded /// 0043565 // sequence-specific DNA binding // not recorded /// 0044212 // transcription regulatory region DNA binding // not recorded 221017_s_at NM_030891 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030891.1 /DEF=Homo sapiens leucine-rich repeat-containing 3 (LRRC3), mRNA. /FEA=mRNA /GEN=LRRC3 /PROD=leucine-rich repeat-containing 3 /DB_XREF=gi:13562087 /FL=gb:NM_030891.1 NM_030891 leucine rich repeat containing 3 LRRC3 81543 NM_030891 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221018_s_at NM_031278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031278.1 /DEF=Homo sapiens tudor domain containing 1 (TDRD1), mRNA. /FEA=mRNA /GEN=TDRD1 /PROD=tudor domain containing 1 /DB_XREF=gi:13775187 /FL=gb:NM_031278.1 NM_031278 tudor domain containing 1 TDRD1 56165 NM_198795 /// XM_005269978 /// XM_005269979 /// XM_006717920 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from sequence or structural similarity /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043186 // P granule // inferred from sequence or structural similarity /// 0071546 // pi-body // inferred from sequence or structural similarity 0046872 // metal ion binding // inferred from electronic annotation 221019_s_at NM_030781 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030781.1 /DEF=Homo sapiens scavenger receptor with C-type lectin (SRCL), mRNA. /FEA=mRNA /GEN=SRCL /PROD=scavenger receptor with C-type lectin /DB_XREF=gi:13540552 /FL=gb:NM_030781.1 NM_030781 collectin sub-family member 12 COLEC12 81035 NM_030781 /// NM_130386 /// XM_006722358 0002221 // pattern recognition receptor signaling pathway // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006910 // phagocytosis, recognition // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0009756 // carbohydrate mediated signaling // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051260 // protein homooligomerization // non-traceable author statement 0005581 // collagen trimer // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005044 // scavenger receptor activity // traceable author statement /// 0005534 // galactose binding // non-traceable author statement /// 0008329 // signaling pattern recognition receptor activity // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221020_s_at NM_030780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030780.1 /DEF=Homo sapiens folate transportercarrier (LOC81034), mRNA. /FEA=mRNA /GEN=LOC81034 /PROD=folate transportercarrier /DB_XREF=gi:13540550 /FL=gb:NM_030780.1 NM_030780 solute carrier family 25 (mitochondrial folate carrier), member 32 SLC25A32 81034 NM_030780 /// NR_102337 /// NR_102338 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015884 // folic acid transport // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0008517 // folic acid transporter activity // non-traceable author statement 221021_s_at NM_030877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030877.1 /DEF=Homo sapiens similar to Bos taurus P14 protein (P14L), mRNA. /FEA=mRNA /GEN=P14L /PROD=similar to Bos taurus P14 protein /DB_XREF=gi:13549248 /FL=gb:NM_030877.1 NM_030877 catenin, beta like 1 CTNNBL1 56259 NM_001281495 /// NM_030877 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016445 // somatic diversification of immunoglobulins // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 221022_s_at NM_031293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031293.1 /DEF=Homo sapiens hypothetical protein DKFZp434G131 (DKFZP434G131), mRNA. /FEA=mRNA /GEN=DKFZP434G131 /PROD=hypothetical protein DKFZp434G131 /DB_XREF=gi:13775211 /FL=gb:NM_031293.1 NM_031293 polyamine modulated factor 1 binding protein 1 PMFBP1 83449 NM_001160213 /// NM_031293 /// XM_005256187 /// XM_006721293 /// XM_006721294 /// XR_429732 0005737 // cytoplasm // inferred from electronic annotation 221023_s_at NM_030779 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030779.1 /DEF=Homo sapiens Eag-related gene member 2 (ERG2), mRNA. /FEA=mRNA /GEN=ERG2 /PROD=Eag-related gene member 2 /DB_XREF=gi:13540548 /FL=gb:NM_030779.1 NM_030779 potassium voltage-gated channel, subfamily H (eag-related), member 6 KCNH6 81033 NM_001278919 /// NM_001278920 /// NM_030779 /// NM_173092 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // not recorded /// 0005267 // potassium channel activity // inferred from electronic annotation 221024_s_at NM_030777 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030777.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 10 (SLC2A10), mRNA. /FEA=mRNA /GEN=SLC2A10 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 10 /DB_XREF=gi:13540546 /FL=gb:NM_030777.1 NM_030777 solute carrier family 2 (facilitated glucose transporter), member 10 SLC2A10 81031 NM_030777 /// XM_006723879 /// XM_006723880 /// XR_430314 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0015992 // proton transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // non-traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 221025_x_at NM_031292 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031292.1 /DEF=Homo sapiens hypothetical protein DKFZp434G1415 (DKFZP434G1415), mRNA. /FEA=mRNA /GEN=DKFZP434G1415 /PROD=hypothetical protein DKFZp434G1415 /DB_XREF=gi:13775209 /FL=gb:NM_031292.1 NM_031292 pseudouridylate synthase 7 homolog (S. cerevisiae)-like PUS7L 83448 NM_001098614 /// NM_001098615 /// NM_001271826 /// NM_031292 /// XM_005269166 /// XM_005269168 /// XM_006719623 /// XM_006719624 /// XR_245959 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 221026_s_at NM_031309 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031309.1 /DEF=Homo sapiens scratch (SCRT), mRNA. /FEA=mRNA /GEN=SCRT /PROD=scratch /DB_XREF=gi:13775235 /FL=gb:NM_031309.1 NM_031309 scratch family zinc finger 1 SCRT1 83482 NM_031309 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221027_s_at NM_030821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030821.1 /DEF=Homo sapiens group XII secreted phospholipase A2 (PLA2G12), mRNA. /FEA=mRNA /GEN=PLA2G12 /PROD=group XII secreted phospholipase A2 /DB_XREF=gi:13540619 /FL=gb:NM_030821.1 NM_030821 phospholipase A2, group XIIA PLA2G12A 81579 NM_030821 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // non-traceable author statement 221028_s_at NM_030819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030819.1 /DEF=Homo sapiens hypothetical protein MGC11335 (MGC11335), mRNA. /FEA=mRNA /GEN=MGC11335 /PROD=hypothetical protein MGC11335 /DB_XREF=gi:13540615 /FL=gb:NM_030819.1 NM_030819 glucose-fructose oxidoreductase domain containing 2 GFOD2 81577 NM_001243650 /// NM_030819 /// NR_027398 /// XM_006721288 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 221029_s_at NM_030775 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030775.1 /DEF=Homo sapiens WNT5b protein (WNT5B), mRNA. /FEA=mRNA /GEN=WNT5B /PROD=WNT5b protein /DB_XREF=gi:13540540 /FL=gb:NM_030775.1 NM_030775 wingless-type MMTV integration site family, member 5B WNT5B 81029 NM_030775 /// NM_032642 /// XM_005253792 /// XM_006719019 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045444 // fat cell differentiation // non-traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // not recorded 221030_s_at NM_031305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031305.1 /DEF=Homo sapiens hypothetical protein DKFZp564B1162 (DKFZP564B1162), mRNA. /FEA=mRNA /GEN=DKFZP564B1162 /PROD=hypothetical protein DKFZp564B1162 /DB_XREF=gi:13775229 /FL=gb:NM_031305.1 NM_031305 Rho GTPase activating protein 24 ARHGAP24 83478 NM_001025616 /// NM_001042669 /// NM_001287805 /// NM_031305 /// XM_005263263 0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 1900028 // negative regulation of ruffle assembly // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 221031_s_at NM_030817 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030817.1 /DEF=Homo sapiens hypothetical protein DKFZp434F0318 (DKFZP434F0318), mRNA. /FEA=mRNA /GEN=DKFZP434F0318 /PROD=hypothetical protein DKFZp434F0318 /DB_XREF=gi:13540611 /FL=gb:NM_030817.1 NM_030817 apolipoprotein L domain containing 1 APOLD1 81575 NM_001130415 /// NM_030817 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0045601 // regulation of endothelial cell differentiation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation 221032_s_at NM_030770 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030770.1 /DEF=Homo sapiens spinesin (LOC80975), mRNA. /FEA=mRNA /GEN=LOC80975 /PROD=spinesin /DB_XREF=gi:13540534 /FL=gb:NM_030770.1 NM_030770 transmembrane protease, serine 5 TMPRSS5 80975 NM_001288749 /// NM_001288750 /// NM_001288751 /// NM_001288752 /// NM_030770 /// NR_110046 /// NR_110047 /// XM_006718921 /// XM_006718922 /// XM_006718923 0006508 // proteolysis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221033_s_at NM_031277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031277.1 /DEF=Homo sapiens ring finger protein 17 (RNF17), mRNA. /FEA=mRNA /GEN=RNF17 /PROD=ring finger protein 17 /DB_XREF=gi:13775185 /FL=gb:NM_031277.1 NM_031277 ring finger protein 17 RNF17 56163 NM_001184993 /// NM_031277 /// NM_031994 /// XM_005266473 /// XM_006719846 /// XM_006719847 /// XM_006719848 /// XM_006719849 /// XM_006719850 /// XM_006719851 /// XM_006719852 /// XM_006719853 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221034_s_at NM_031273 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031273.1 /DEF=Homo sapiens testis expressed sequence 13B (TEX13B), mRNA. /FEA=mRNA /GEN=TEX13B /PROD=testis expressed sequence 13B /DB_XREF=gi:13775177 /FL=gb:NM_031273.1 NM_031273 testis expressed 13B TEX13B 56156 NM_031273 221035_s_at NM_031272 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031272.1 /DEF=Homo sapiens testis expressed sequence 14 (TEX14), mRNA. /FEA=mRNA /GEN=TEX14 /PROD=testis expressed sequence 14 /DB_XREF=gi:13775175 /FL=gb:NM_031272.1 NM_031272 testis expressed 14 TEX14 56155 NM_001201457 /// NM_031272 /// NM_198393 /// XM_005257518 /// XM_005257519 /// XM_006721976 /// XM_006721977 /// XM_006721978 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from sequence or structural similarity /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from sequence or structural similarity /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032466 // negative regulation of cytokinesis // inferred from electronic annotation /// 0043063 // intercellular bridge organization // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0051306 // mitotic sister chromatid separation // inferred from sequence or structural similarity 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from sequence or structural similarity /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005623 // cell // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030496 // midbody // inferred from sequence or structural similarity /// 0045171 // intercellular bridge // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 221036_s_at NM_031301 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031301.1 /DEF=Homo sapiens hypothetical protein DKFZp564D0372 (DKFZP564D0372), mRNA. /FEA=mRNA /GEN=DKFZP564D0372 /PROD=hypothetical protein DKFZp564D0372 /DB_XREF=gi:13775223 /FL=gb:NM_031301.1 NM_031301 APH1B gamma secretase subunit APH1B 83464 NM_001145646 /// NM_031301 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay 221037_s_at NM_031291 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031291.1 /DEF=Homo sapiens hypothetical protein DKFZp434N1235 (DKFZP434N1235), mRNA. /FEA=mRNA /GEN=DKFZP434N1235 /PROD=hypothetical protein DKFZp434N1235 /DB_XREF=gi:13775207 /FL=gb:NM_031291.1 NM_031291 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 SLC25A31 83447 NM_031291 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 221038_at NM_018610 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018610.1 /DEF=Homo sapiens hypothetical protein PRO1942 (PRO1942), mRNA. /FEA=mRNA /GEN=PRO1942 /PROD=hypothetical protein PRO1942 /DB_XREF=gi:8924099 /UG=Hs.100134 hypothetical protein PRO1942 /FL=gb:AF116675.1 gb:NM_018610.1 NM_018610 221039_s_at NM_018482 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018482.1 /DEF=Homo sapiens KIAA1249 protein (KIAA1249), mRNA. /FEA=mRNA /GEN=KIAA1249 /PROD=uncharacterized gastric protein ZG14P /DB_XREF=gi:8923867 /UG=Hs.10669 KIAA1249 protein /FL=gb:AF222859.1 gb:NM_018482.1 NM_018482 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ASAP1 50807 NM_001247996 /// NM_018482 /// XM_005250925 /// XM_006716563 /// XM_006716564 /// XM_006716565 /// XM_006716566 /// XM_006716567 0030030 // cell projection organization // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221040_at NM_023089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023089.1 /DEF=Homo sapiens calpain 10 (CAPN10), transcript variant 7, mRNA. /FEA=mRNA /GEN=CAPN10 /PROD=calpain 10, isoform g /DB_XREF=gi:13186313 /UG=Hs.112218 calpain 10 /FL=gb:AF089095.1 gb:NM_023089.1 NM_023089 calpain 10 CAPN10 11132 NM_021251 /// NM_023083 /// NM_023084 /// NM_023085 /// NM_023086 /// NM_023087 /// NM_023088 /// NM_023089 0006508 // proteolysis // inferred from mutant phenotype /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // inferred by curator /// 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032388 // positive regulation of intracellular transport // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0097050 // type B pancreatic cell apoptotic process // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000676 // positive regulation of type B pancreatic cell apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005623 // cell // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0000149 // SNARE binding // inferred from sequence or structural similarity /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221041_s_at NM_012434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012434.1 /DEF=Homo sapiens solute carrier family 17 (anionsugar transporter), member 5 (SLC17A5), mRNA. /FEA=mRNA /GEN=SLC17A5 /PROD=solute carrier family 17 (anionsugartransporter), member 5 /DB_XREF=gi:6912665 /UG=Hs.117865 solute carrier family 17 (anionsugar transporter), member 5 /FL=gb:NM_012434.1 NM_012434 solute carrier family 17 (acidic sugar transporter), member 5 SLC17A5 26503 NM_012434 /// XM_005248710 /// XM_005248711 /// XM_006715459 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015739 // sialic acid transport // inferred from direct assay /// 0015992 // proton transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005351 // sugar:proton symporter activity // traceable author statement /// 0015136 // sialic acid transmembrane transporter activity // inferred from direct assay /// 0015293 // symporter activity // inferred from electronic annotation 221042_s_at NM_024734 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024734.1 /DEF=Homo sapiens hypothetical protein FLJ12383 (FLJ12383), mRNA. /FEA=mRNA /GEN=FLJ12383 /PROD=hypothetical protein FLJ12383 /DB_XREF=gi:13376053 /UG=Hs.118164 hypothetical protein FLJ12383 /FL=gb:NM_024734.1 NM_024734 calmin (calponin-like, transmembrane) CLMN 79789 NM_024734 /// XM_006720256 /// XR_245721 /// XR_245722 /// XR_429330 /// XR_429331 /// XR_429332 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221043_at NM_013395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013395.1 /DEF=Homo sapiens proteinx0008 (AD013), mRNA. /FEA=mRNA /GEN=AD013 /PROD=proteinx0008 /DB_XREF=gi:7019320 /UG=Hs.125294 proteinx0008 /FL=gb:AF150735.1 gb:NM_013395.1 NM_013395 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation 221044_s_at NM_021616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021616.1 /DEF=Homo sapiens ring finger protein 21, interferon-responsive (RNF21), mRNA. /FEA=mRNA /GEN=RNF21 /PROD=ring finger protein 21, interferon-responsive /DB_XREF=gi:11055977 /UG=Hs.125300 ring finger protein 21, interferon-responsive /FL=gb:AB039903.1 gb:NM_021616.1 NM_021616 tripartite motif containing 34 /// TRIM6-TRIM34 readthrough TRIM34 /// TRIM6-TRIM34 53840 /// 445372 NM_001003819 /// NM_001003827 /// NM_021616 /// NM_130389 /// NM_130390 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0070206 // protein trimerization // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221045_s_at NM_016831 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016831.1 /DEF=Homo sapiens period (Drosophila) homolog 3 (PER3), mRNA. /FEA=mRNA /GEN=PER3 /PROD=period 3 /DB_XREF=gi:8567387 /UG=Hs.12592 period (Drosophila) homolog 3 /FL=gb:NM_016831.1 NM_016831 period circadian clock 3 PER3 8863 NM_001289861 /// NM_001289862 /// NM_001289863 /// NM_001289864 /// NM_016831 /// XM_005263520 /// XM_005263521 /// XM_005263522 /// XM_005263523 /// XM_005263524 /// XM_005263527 /// XM_005263528 /// XM_005263529 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221046_s_at NM_014170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014170.1 /DEF=Homo sapiens HSPC135 protein (HSPC135), mRNA. /FEA=mRNA /GEN=HSPC135 /PROD=HSPC135 protein /DB_XREF=gi:7661795 /UG=Hs.127496 HSPC135 protein /FL=gb:AF161484.1 gb:NM_014170.1 NM_014170 GTP-binding protein 8 (putative) GTPBP8 29083 NM_001008235 /// NM_001008236 /// NM_014170 /// NM_138485 /// XR_241486 0000917 // barrier septum assembly // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221047_s_at NM_018650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018650.1 /DEF=Homo sapiens MARK (MARK), mRNA. /FEA=mRNA /GEN=MARK /PROD=MARK /DB_XREF=gi:8923921 /UG=Hs.12808 MARK /FL=gb:AF154845.1 gb:NM_018650.1 NM_018650 MAP/microtubule affinity-regulating kinase 1 MARK1 4139 NM_001286124 /// NM_001286126 /// NM_001286128 /// NM_001286129 /// NM_018650 /// XM_005273134 /// XM_006711326 /// XM_006711327 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0001786 // phosphatidylserine binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity /// 0070300 // phosphatidic acid binding // inferred from direct assay 221048_x_at NM_017941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017941.1 /DEF=Homo sapiens hypothetical protein FLJ20721 (FLJ20721), mRNA. /FEA=mRNA /GEN=FLJ20721 /PROD=hypothetical protein FLJ20721 /DB_XREF=gi:8923646 /UG=Hs.12929 hypothetical protein FLJ20721 /FL=gb:NM_017941.1 NM_017941 chromosome 17 open reading frame 80 C17orf80 55028 NM_001100621 /// NM_001100622 /// NM_001288770 /// NM_001288771 /// NM_017941 /// NR_110105 /// XM_005257487 /// XM_006721966 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221049_s_at NM_013274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013274.1 /DEF=Homo sapiens polymerase (DNA-directed), lambda (POLL), mRNA. /FEA=mRNA /GEN=POLL /PROD=polymerase (DNA-directed), lambda /DB_XREF=gi:7019490 /UG=Hs.129903 polymerase (DNA-directed), lambda /FL=gb:NM_013274.1 NM_013274 polymerase (DNA directed), lambda POLL 27343 NM_001174084 /// NM_001174085 /// NM_013274 /// NR_033406 /// XM_006717770 /// XM_006717771 /// XM_006717772 /// XM_006717773 /// XM_006717774 /// XM_006717775 /// XM_006717776 /// XM_006717777 /// XM_006717778 /// XM_006717779 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // non-traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // non-traceable author statement 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221050_s_at NM_019096 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019096.1 /DEF=Homo sapiens GTP binding protein 2 (GTPBP2), mRNA. /FEA=mRNA /GEN=GTPBP2 /PROD=GTP binding protein 2 /DB_XREF=gi:9506762 /UG=Hs.13011 GTP binding protein 2 /FL=gb:NM_019096.1 NM_019096 GTP binding protein 2 GTPBP2 54676 NM_001286216 /// NM_019096 /// XM_006715124 0006184 // GTP catabolic process // inferred from electronic annotation 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 221051_s_at NM_014446 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014446.1 /DEF=Homo sapiens muscle-specific beta 1 integrin binding protein (MIBP), mRNA. /FEA=mRNA /GEN=MIBP /PROD=muscle-specific beta 1 integrin binding protein /DB_XREF=gi:7657330 /UG=Hs.135458 muscle-specific beta 1 integrin binding protein /FL=gb:AF190819.1 gb:NM_014446.1 NM_014446 nicotinamide riboside kinase 2 NMRK2 27231 NM_001289117 /// NM_014446 /// NM_170678 /// NR_110316 /// XM_006722725 /// XM_006722726 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019359 // nicotinamide nucleotide biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050262 // ribosylnicotinamide kinase activity // inferred from electronic annotation 221052_at NM_006862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006862.2 /DEF=Homo sapiens putative RNA binding protein (TDRKH), mRNA. /FEA=mRNA /GEN=TDRKH /PROD=putative RNA binding protein /DB_XREF=gi:6755759 /UG=Hs.144439 putative RNA binding protein /FL=gb:AF119121.2 gb:NM_006862.2 NM_006862 tudor and KH domain containing TDRKH 11022 NM_001083963 /// NM_001083964 /// NM_001083965 /// NM_006862 /// XM_005244853 /// XM_005244854 /// XM_005244856 /// XR_426761 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0009566 // fertilization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0071546 // pi-body // inferred from sequence or structural similarity /// 0071547 // piP-body // inferred from sequence or structural similarity 0003723 // RNA binding // inferred from electronic annotation 221053_s_at NM_006862 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006862.2 /DEF=Homo sapiens putative RNA binding protein (TDRKH), mRNA. /FEA=mRNA /GEN=TDRKH /PROD=putative RNA binding protein /DB_XREF=gi:6755759 /UG=Hs.144439 putative RNA binding protein /FL=gb:AF119121.2 gb:NM_006862.2 NM_006862 tudor and KH domain containing TDRKH 11022 NM_001083963 /// NM_001083964 /// NM_001083965 /// NM_006862 /// XM_005244853 /// XM_005244854 /// XM_005244856 /// XR_426761 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0009566 // fertilization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0071546 // pi-body // inferred from sequence or structural similarity /// 0071547 // piP-body // inferred from sequence or structural similarity 0003723 // RNA binding // inferred from electronic annotation 221054_s_at NM_014418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014418.1 /DEF=Homo sapiens T-cell leukemialymphoma 6 (TCL6), transcript variant TCL6a2, mRNA. /FEA=mRNA /GEN=TCL6 /PROD=T-cell leukemialymphoma 6, isoform TCL6a2 /DB_XREF=gi:10947104 /UG=Hs.144519 T-cell leukemialymphoma 6 /FL=gb:NM_014418.1 gb:AB035333.1 NM_014418 T-cell leukemia/lymphoma 6 (non-protein coding) TCL6 27004 NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NR_028288 221056_x_at NM_021235 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021235.1 /DEF=Homo sapiens epidermal growth factor receptor substrate EPS15R (EPS15R), mRNA. /FEA=mRNA /GEN=EPS15R /PROD=epidermal growth factor receptor substrateEPS15R /DB_XREF=gi:10864046 /UG=Hs.147176 epidermal growth factor receptor substrate EPS15R /FL=gb:NM_021235.1 gb:AF110265.1 NM_021235 epidermal growth factor receptor pathway substrate 15-like 1 EPS15L1 58513 NM_001258374 /// NM_001258375 /// NM_001258376 /// NM_021235 /// NR_047665 /// NR_047666 /// XM_006722823 /// XM_006722824 /// XM_006722825 /// XM_006722826 /// XM_006722827 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221057_at NM_022354 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022354.1 /DEF=Homo sapiens spermatogenesis associated protein 1 (SPAP1), mRNA. /FEA=mRNA /GEN=SPAP1 /PROD=spermatogenesis associated protein 1 /DB_XREF=gi:11641266 /UG=Hs.147403 spermatogenesis associated 1 /FL=gb:AF306347.1 gb:NM_022354.1 NM_022354 spermatogenesis associated 1 SPATA1 100505741 NM_001081472 /// NM_022354 /// XM_003118960 /// XM_003119805 /// XM_003960123 /// XM_005271374 /// XM_005275883 /// XM_005276137 /// XM_006710076 /// XM_006711087 /// XM_006726336 /// XR_246362 /// XR_248842 /// XR_250776 221058_s_at NM_016326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016326.2 /DEF=Homo sapiens chemokine-like factor 3, alternatively spliced (LOC51192), mRNA. /FEA=mRNA /GEN=LOC51192 /PROD=chemokine-like factor 3, alternatively spliced /DB_XREF=gi:10092611 /UG=Hs.15159 chemokine-like factor, alternatively spliced /FL=gb:NM_016326.2 gb:AF135381.2 NM_016326 chemokine-like factor CKLF 51192 NM_001040138 /// NM_001040139 /// NM_016326 /// NM_016951 /// NM_181640 /// NM_181641 0006935 // chemotaxis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0032940 // secretion by cell // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0048247 // lymphocyte chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay 221059_s_at NM_021615 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021615.1 /DEF=Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 (CHST6), mRNA. /FEA=mRNA /GEN=CHST6 /PROD=carbohydrate (N-acetylglucosamine 6-O)sulfotransferase 6 /DB_XREF=gi:11055975 /UG=Hs.157439 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 /FL=gb:AF219990.1 gb:NM_021615.1 NM_021615 coactosin-like F-actin binding protein 1 COTL1 23406 NM_021149 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred by curator /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050832 // defense response to fungus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // traceable author statement /// 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 221060_s_at NM_003266 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003266.1 /DEF=Homo sapiens toll-like receptor 4 (TLR4), mRNA. /FEA=mRNA /GEN=TLR4 /PROD=toll-like receptor 4 /DB_XREF=gi:4507532 /UG=Hs.159239 toll-like receptor 4 /FL=gb:U88880.1 gb:NM_003266.1 NM_003266 toll-like receptor 4 TLR4 7099 NM_003266 /// NM_138554 /// NM_138556 /// NM_138557 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0002218 // activation of innate immune response // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002322 // B cell proliferation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002537 // nitric oxide production involved in inflammatory response // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0016046 // detection of fungus // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from genetic interaction /// 0032496 // response to lipopolysaccharide // inferred by curator /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032707 // negative regulation of interleukin-23 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032732 // positive regulation of interleukin-1 production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from sequence or structural similarity /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042088 // T-helper 1 type immune response // non-traceable author statement /// 0042116 // macrophage activation // inferred from mutant phenotype /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045348 // positive regulation of MHC class II biosynthetic process // inferred from electronic annotation /// 0045359 // positive regulation of interferon-beta biosynthetic process // inferred from electronic annotation /// 0045416 // positive regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050829 // defense response to Gram-negative bacterium // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0060729 // intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070430 // positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070434 // positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071223 // cellular response to lipoteichoic acid // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from mutant phenotype /// 0001530 // lipopolysaccharide binding // non-traceable author statement /// 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221061_at NM_016112 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016112.1 /DEF=Homo sapiens polycystic kidney disease 2-like 1 (PKD2L1), mRNA. /FEA=mRNA /GEN=PKD2L1 /PROD=polycystic kidney disease 2-like 1 /DB_XREF=gi:7706638 /UG=Hs.159241 polycystic kidney disease 2-like 1 /FL=gb:AF073481.1 gb:NM_016112.1 NM_016112 polycystic kidney disease 2-like 1 PKD2L1 9033 NM_001253837 /// NM_016112 0001581 // detection of chemical stimulus involved in sensory perception of sour taste // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050915 // sensory perception of sour taste // inferred from mutant phenotype /// 0050982 // detection of mechanical stimulus // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071468 // cellular response to acidity // inferred from sequence or structural similarity /// 0071805 // potassium ion transmembrane transport // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0034704 // calcium channel complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005227 // calcium activated cation channel activity // inferred from direct assay /// 0005261 // cation channel activity // inferred from direct assay /// 0005262 // calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from direct assay /// 0005272 // sodium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008324 // cation transmembrane transporter activity // inferred from sequence or structural similarity /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0033040 // sour taste receptor activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0051371 // muscle alpha-actinin binding // inferred from physical interaction /// 0051393 // alpha-actinin binding // inferred from physical interaction 221062_at NM_006041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006041.1 /DEF=Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 (HS3ST3B1), mRNA. /FEA=mRNA /GEN=HS3ST3B1 /PROD=heparan sulfate D-glucosaminyl3-O-sulfotransferase 3B1 /DB_XREF=gi:5174466 /UG=Hs.159572 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 /FL=gb:AF105377.1 gb:NM_006041.1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 HS3ST3B1 9953 NM_006041 /// XR_243575 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // traceable author statement /// 0015015 // heparan sulfate proteoglycan biosynthetic process, enzymatic modification // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008467 // [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0033872 // [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity // inferred from electronic annotation 221063_x_at NM_022064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022064.1 /DEF=Homo sapiens hypothetical protein FLJ12565 (FLJ12565), mRNA. /FEA=mRNA /GEN=FLJ12565 /PROD=hypothetical protein FLJ12565 /DB_XREF=gi:11545772 /UG=Hs.16036 hypothetical protein FLJ12565 /FL=gb:NM_022064.1 NM_022064 ring finger protein 123 RNF123 63891 NM_022064 /// XM_006713285 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221064_s_at NM_023076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023076.1 /DEF=Homo sapiens hypothetical protein FLJ23360 (FLJ23360), mRNA. /FEA=mRNA /GEN=FLJ23360 /PROD=hypothetical protein FLJ23360 /DB_XREF=gi:12751488 /UG=Hs.161279 hypothetical protein FLJ23360 /FL=gb:NM_023076.1 NM_023076 unkempt family zinc finger-like UNKL 64718 NM_001037125 /// NM_001193388 /// NM_001193389 /// NM_001276414 /// NM_023076 /// XM_005255505 /// XM_005255506 /// XM_006720923 /// XM_006720924 /// XM_006720925 /// XR_429645 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221065_s_at NM_022467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022467.1 /DEF=Homo sapiens N-acetylgalactosamine-4-O-sulfotransferase (GALNAC-4-ST1), mRNA. /FEA=mRNA /GEN=GALNAC-4-ST1 /PROD=N-acetylgalactosamine-4-O-sulfotransferase /DB_XREF=gi:11968014 /UG=Hs.165724 N-acetylgalactosamine-4-O-sulfotransferase /FL=gb:AF300612.1 gb:NM_022467.1 NM_022467 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 CHST8 64377 NM_001127895 /// NM_001127896 /// NM_022467 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0007417 // central nervous system development // non-traceable author statement /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from expression pattern 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001537 // N-acetylgalactosamine 4-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221066_at NM_016568 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016568.1 /DEF=Homo sapiens G-protein coupled receptor SALPR; somatostatin and angiotensin-like peptide receptor (LOC51289), mRNA. /FEA=mRNA /GEN=LOC51289 /PROD=G-protein coupled receptor SALPR; somatostatinand angiotensin-like peptide receptor /DB_XREF=gi:7706102 /UG=Hs.170146 G-protein coupled receptor SALPR; somatostatin and angiotensin-like peptide receptor /FL=gb:D88437.1 gb:NM_016568.1 NM_016568 relaxin/insulin-like family peptide receptor 3 RXFP3 51289 NM_016568 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // inferred from electronic annotation 221067_s_at NM_030572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030572.1 /DEF=Homo sapiens hypothetical protein MGC10946 (MGC10946), mRNA. /FEA=mRNA /GEN=MGC10946 /PROD=hypothetical protein MGC10946 /DB_XREF=gi:13386481 /UG=Hs.170994 hypothetical protein MGC10946 /FL=gb:BC004336.1 gb:NM_030572.1 NM_030572 spexin hormone SPX 80763 NM_030572 0003084 // positive regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0035814 // negative regulation of renal sodium excretion // inferred from sequence or structural similarity /// 0044539 // long-chain fatty acid import // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005184 // neuropeptide hormone activity // inferred from direct assay /// 0031765 // type 2 galanin receptor binding // inferred from direct assay /// 0031766 // type 3 galanin receptor binding // inferred from direct assay 221068_at NM_017616 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017616.1 /DEF=Homo sapiens hypothetical protein FLJ20004 (FLJ20004), mRNA. /FEA=mRNA /GEN=FLJ20004 /PROD=hypothetical protein FLJ20004 /DB_XREF=gi:8923010 /UG=Hs.17311 hypothetical protein FLJ20004 /FL=gb:NM_017616.1 NM_017616 KN motif and ankyrin repeat domains 2 KANK2 25959 NM_001136191 /// NM_015493 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221069_s_at NM_016360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016360.1 /DEF=Homo sapiens clone HQ0477 PRO0477p (LOC51204), mRNA. /FEA=mRNA /GEN=LOC51204 /PROD=clone HQ0477 PRO0477p /DB_XREF=gi:7705952 /UG=Hs.174134 clone HQ0477 PRO0477p /FL=gb:AF090929.1 gb:NM_016360.1 NM_016360 translational activator of mitochondrially encoded cytochrome c oxidase I TACO1 51204 NM_016360 0006417 // regulation of translation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 221070_s_at NM_021174 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021174.1 /DEF=Homo sapiens p30 DBC protein (LOC57805), mRNA. /FEA=mRNA /GEN=LOC57805 /PROD=p30 DBC protein /DB_XREF=gi:10863970 /UG=Hs.181102 p30 DBC protein /FL=gb:NM_021174.1 NM_021174 cell cycle and apoptosis regulator 2 CCAR2 57805 NM_021174 /// NM_199205 /// NR_033902 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0009411 // response to UV // inferred from mutant phenotype /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from mutant phenotype /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 2000003 // positive regulation of DNA damage checkpoint // inferred from mutant phenotype 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0044609 // DBIRD complex // inferred from direct assay 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221071_at NM_021651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021651.1 /DEF=Homo sapiens PRO0457 protein (PRO0457), mRNA. /FEA=mRNA /GEN=PRO0457 /PROD=PRO0457 protein /DB_XREF=gi:11067366 /UG=Hs.192705 PRO0457 protein /FL=gb:NM_021651.1 gb:AF090927.1 NM_021651 221072_at NM_020250 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020250.1 /DEF=Homo sapiens MOST2 protein (MOST2), mRNA. /FEA=mRNA /GEN=MOST2 /PROD=MOST2 protein /DB_XREF=gi:9910449 /UG=Hs.193920 MOST2 protein /FL=gb:AF220263.1 gb:NM_020250.1 NM_020250 GSN antisense RNA 1 GSN-AS1 57000 NM_020250 /// NR_103560 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051014 // actin filament severing // inferred from direct assay /// 0051014 // actin filament severing // inferred from sequence or structural similarity /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221073_s_at NM_006092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006092.1 /DEF=Homo sapiens caspase recruitment domain 4 (NOD1), mRNA. /FEA=mRNA /GEN=NOD1 /PROD=caspase recruitment domain 4 /DB_XREF=gi:5174616 /UG=Hs.19405 caspase recruitment domain 4 /FL=gb:AF113925.1 gb:NM_006092.1 NM_006092 nucleotide-binding oligomerization domain containing 1 NOD1 10392 NM_006092 /// XM_005249568 /// XM_005249572 /// XM_005249573 /// XM_005249574 /// XM_005249575 /// XM_005249576 /// XM_006715633 /// XM_006715634 /// XM_006715635 /// XM_006715636 /// XM_006715637 /// XR_428069 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0009595 // detection of biotic stimulus // traceable author statement /// 0016045 // detection of bacterium // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042228 // interleukin-8 biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042834 // peptidoglycan binding // traceable author statement /// 0050700 // CARD domain binding // inferred from direct assay 221074_at NM_004828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004828.1 /DEF=Homo sapiens lymphocyte antigen 95 (activating NK-receptor ; NK-p44) (LY95), mRNA. /FEA=mRNA /GEN=LY95 /PROD=lymphocyte antigen 95 (activating NK-receptor ;NK-p44) /DB_XREF=gi:4758693 /UG=Hs.194721 lymphocyte antigen 95 (activating NK-receptor ; NK-p44) /FL=gb:NM_004828.1 NM_004828 221075_s_at NM_004828 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004828.1 /DEF=Homo sapiens lymphocyte antigen 95 (activating NK-receptor ; NK-p44) (LY95), mRNA. /FEA=mRNA /GEN=LY95 /PROD=lymphocyte antigen 95 (activating NK-receptor ;NK-p44) /DB_XREF=gi:4758693 /UG=Hs.194721 lymphocyte antigen 95 (activating NK-receptor ; NK-p44) /FL=gb:NM_004828.1 NM_004828 natural cytotoxicity triggering receptor 2 NCR2 9436 NM_001199509 /// NM_001199510 /// NM_004828 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221076_at NM_014100 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014100.1 /DEF=Homo sapiens PRO1770 protein (PRO1770), mRNA. /FEA=mRNA /GEN=PRO1770 /PROD=PRO1770 protein /DB_XREF=gi:7662612 /UG=Hs.196972 PRO1770 protein /FL=gb:AF118075.1 gb:NM_014100.1 NM_014100 pelota homolog (Drosophila) PELO 53918 NM_015946 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042311 // vasodilation // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045123 // cellular extravasation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070481 // nuclear-transcribed mRNA catabolic process, non-stop decay // inferred from electronic annotation /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from electronic annotation /// 0071025 // RNA surveillance // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // inferred from electronic annotation /// 0008305 // integrin complex // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0005518 // collagen binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221077_at NM_018076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018076.1 /DEF=Homo sapiens hypothetical protein FLJ10376 (FLJ10376), mRNA. /FEA=mRNA /GEN=FLJ10376 /PROD=hypothetical protein FLJ10376 /DB_XREF=gi:8922385 /UG=Hs.202289 hypothetical protein FLJ10376 /FL=gb:NM_018076.1 NM_018076 armadillo repeat containing 4 ARMC4 55130 NM_001290020 /// NM_001290021 /// NM_018076 /// XM_005252485 /// XM_006717453 /// XM_006717454 /// XM_006717455 0030030 // cell projection organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0097546 // ciliary base // inferred from direct assay 221078_s_at NM_018084 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018084.1 /DEF=Homo sapiens hypothetical protein FLJ10392 (FLJ10392), mRNA. /FEA=mRNA /GEN=FLJ10392 /PROD=hypothetical protein FLJ10392 /DB_XREF=gi:8922402 /UG=Hs.20887 hypothetical protein FLJ10392 /FL=gb:NM_018084.1 NM_018084 coiled-coil domain containing 88A CCDC88A 55704 NM_001135597 /// NM_001254943 /// NM_018084 /// XM_005264418 /// XM_005264421 /// XM_005264423 /// XM_005264426 /// XM_005264427 0001932 // regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031929 // TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0061024 // membrane organization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043422 // protein kinase B binding // inferred from physical interaction 221079_s_at NM_018396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018396.1 /DEF=Homo sapiens hypothetical protein FLJ11350 (FLJ11350), mRNA. /FEA=mRNA /GEN=FLJ11350 /PROD=hypothetical protein FLJ11350 /DB_XREF=gi:8923004 /UG=Hs.233694 hypothetical protein FLJ11350 /FL=gb:NM_018396.1 NM_018396 methyltransferase like 2A /// methyltransferase like 2B METTL2A /// METTL2B 55798 /// 339175 NM_001005372 /// NM_018396 /// NM_181725 0008152 // metabolic process // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from mutant phenotype /// 0030488 // tRNA methylation // inferred from sequence or structural similarity /// 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016427 // tRNA (cytosine) methyltransferase activity // inferred from mutant phenotype /// 0016427 // tRNA (cytosine) methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation 221080_s_at NM_024898 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024898.1 /DEF=Homo sapiens hypothetical protein FLJ22757 (FLJ22757), mRNA. /FEA=mRNA /GEN=FLJ22757 /PROD=hypothetical protein FLJ22757 /DB_XREF=gi:13376352 /UG=Hs.236449 hypothetical protein FLJ22757 /FL=gb:NM_024898.1 NM_024898 DENN/MADD domain containing 1C DENND1C 79958 NM_001290331 /// NM_024898 /// XM_005259646 /// XM_006722905 /// XM_006722906 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 221081_s_at NM_024901 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024901.1 /DEF=Homo sapiens hypothetical protein FLJ22457 (FLJ22457), mRNA. /FEA=mRNA /GEN=FLJ22457 /PROD=hypothetical protein FLJ22457 /DB_XREF=gi:13376358 /UG=Hs.238707 hypothetical protein FLJ22457 /FL=gb:NM_024901.1 NM_024901 DENN/MADD domain containing 2D DENND2D 79961 NM_001271833 /// NM_024901 /// XM_006710921 /// XM_006710922 /// XM_006710923 /// XM_006710924 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 221082_s_at NM_022477 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022477.1 /DEF=Homo sapiens hypothetical protein FLJ13556 similar to N-myc downstream regulated 3 (FLJ13556), mRNA. /FEA=mRNA /GEN=FLJ13556 /PROD=hypothetical protein FLJ13556 similar to N-mycdownstream regulated 3 /DB_XREF=gi:11968028 /UG=Hs.240615 hypothetical protein FLJ13556 similar to N-myc downstream regulated 3 /FL=gb:NM_022477.1 NM_022477 NDRG family member 3 NDRG3 57446 NM_022477 /// NM_032013 /// NR_038370 /// XM_006723837 /// XM_006723838 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221083_at NM_004700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004700.1 /DEF=Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), mRNA. /FEA=mRNA /GEN=KCNQ4 /PROD=potassium voltage-gated channel, KQT-likesubfamily, member 4 /DB_XREF=gi:4758631 /UG=Hs.241376 potassium voltage-gated channel, KQT-like subfamily, member 4 /FL=gb:AF105202.1 gb:NM_004700.1 NM_004700 potassium voltage-gated channel, KQT-like subfamily, member 4 KCNQ4 9132 NM_004700 /// NM_172163 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement 221084_at NM_006028 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006028.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3B (HTR3B), mRNA. /FEA=mRNA /GEN=HTR3B /PROD=5-hydroxytryptamine (serotonin) receptor 3B /DB_XREF=gi:5174468 /UG=Hs.241377 5-hydroxytryptamine (serotonin) receptor 3B /FL=gb:AF080582.1 gb:NM_006028.1 gb:AF169255.1 NM_006028 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic HTR3B 9177 NM_006028 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // traceable author statement /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004993 // serotonin receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // traceable author statement /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005232 // serotonin-activated cation-selective channel activity // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // inferred from electronic annotation 221085_at NM_005118 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005118.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 15 (TNFSF15), mRNA. /FEA=mRNA /GEN=TNFSF15 /PROD=tumor necrosis factor (ligand) superfamily,member 15 /DB_XREF=gi:4827031 /UG=Hs.241382 tumor necrosis factor (ligand) superfamily, member 15 /FL=gb:NM_005118.1 NM_005118 tumor necrosis factor (ligand) superfamily, member 15 TNFSF15 9966 NM_001204344 /// NM_005118 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0042107 // cytokine metabolic process // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005102 // receptor binding // traceable author statement /// 0005123 // death receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221086_s_at NM_018008 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018008.1 /DEF=Homo sapiens hypothetical protein FLJ10142 (FLJ10142), mRNA. /FEA=mRNA /GEN=FLJ10142 /PROD=hypothetical protein FLJ10142 /DB_XREF=gi:8922251 /UG=Hs.241523 hypothetical protein FLJ10142 /FL=gb:NM_018008.1 NM_018008 FEZ family zinc finger 2 FEZF2 55079 NM_018008 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021797 // forebrain anterior/posterior pattern specification // inferred from electronic annotation /// 0021853 // cerebral cortex GABAergic interneuron migration // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221087_s_at NM_014349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014349.1 /DEF=Homo sapiens apolipoprotein L, 3 (APOL3), mRNA. /FEA=mRNA /GEN=APOL3 /PROD=apolipoprotein L, 3 /DB_XREF=gi:7656972 /UG=Hs.241535 apolipoprotein L, 3 /FL=gb:AY014905.1 gb:AF070675.1 gb:NM_014349.1 NM_014349 apolipoprotein L, 3 APOL3 80833 NM_014349 /// NM_030644 /// NM_145639 /// NM_145640 /// NM_145641 /// NM_145642 /// NR_027833 /// NR_027834 /// NR_027835 /// XM_006724322 /// XM_006724323 /// XM_006724324 /// XM_006724325 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005319 // lipid transporter activity // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 221088_s_at NM_017650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017650.1 /DEF=Homo sapiens hypothetical protein FLJ20068 (FLJ20068), mRNA. /FEA=mRNA /GEN=FLJ20068 /PROD=hypothetical protein FLJ20068 /DB_XREF=gi:8923072 /UG=Hs.247748 hypothetical protein FLJ20068 /FL=gb:NM_017650.1 NM_017650 protein phosphatase 1, regulatory subunit 9A PPP1R9A 55607 NM_001166160 /// NM_001166161 /// NM_001166162 /// NM_001166163 /// NM_017650 /// XM_005250485 /// XM_006716046 /// XM_006716047 /// XM_006716048 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221089_at NM_015718 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015718.1 /DEF=Homo sapiens NADPH oxidase 3 (NOX3), mRNA. /FEA=mRNA /GEN=NOX3 /PROD=NADPH oxidase 3 /DB_XREF=gi:11136625 /UG=Hs.247776 NADPH oxidase 3 /FL=gb:AF190122.1 gb:NM_015718.1 NM_015718 NADPH oxidase 3 NOX3 50508 NM_015718 0001659 // temperature homeostasis // inferred from electronic annotation /// 0009590 // detection of gravity // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0048840 // otolith development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 221090_s_at NM_018233 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018233.1 /DEF=Homo sapiens hypothetical protein FLJ10826 (FLJ10826), mRNA. /FEA=mRNA /GEN=FLJ10826 /PROD=hypothetical protein FLJ10826 /DB_XREF=gi:8922693 /UG=Hs.24809 hypothetical protein FLJ10826 /FL=gb:NM_018233.1 NM_018233 2-oxoglutarate and iron-dependent oxygenase domain containing 1 OGFOD1 55239 NM_018233 0006449 // regulation of translational termination // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0018126 // protein hydroxylation // inferred from direct assay /// 0019511 // peptidyl-proline hydroxylation // inferred from direct assay /// 0034063 // stress granule assembly // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from mutant phenotype 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0031543 // peptidyl-proline dioxygenase activity // inferred from direct assay /// 0031544 // peptidyl-proline 3-dioxygenase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 221091_at NM_005478 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005478.2 /DEF=Homo sapiens insulin-like 5 (INSL5), mRNA. /FEA=mRNA /GEN=INSL5 /PROD=insulin-like 5 /DB_XREF=gi:5729885 /UG=Hs.251380 insulin-like 5 /FL=gb:AF133816.2 gb:NM_005478.2 NM_005478 insulin-like 5 INSL5 10022 NM_005478 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // inferred from electronic annotation 221092_at NM_012481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012481.1 /DEF=Homo sapiens zinc finger protein, subfamily 1A, 3 (Aiolos) (ZNFN1A3), mRNA. /FEA=mRNA /GEN=ZNFN1A3 /PROD=zinc finger protein, subfamily 1A, 3 (Aiolos) /DB_XREF=gi:6912753 /UG=Hs.258579 zinc finger protein, subfamily 1A, 3 (Aiolos) /FL=gb:AF129512.1 gb:NM_012481.1 NM_012481 IKAROS family zinc finger 3 (Aiolos) IKZF3 22806 NM_001257408 /// NM_001257409 /// NM_001257410 /// NM_001257411 /// NM_001257412 /// NM_001257413 /// NM_001257414 /// NM_001284514 /// NM_001284515 /// NM_001284516 /// NM_012481 /// NM_183228 /// NM_183229 /// NM_183230 /// NM_183231 /// NM_183232 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0030888 // regulation of B cell proliferation // inferred from sequence or structural similarity /// 0042113 // B cell activation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0045577 // regulation of B cell differentiation // inferred from sequence or structural similarity /// 0045619 // regulation of lymphocyte differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 221093_at NM_012107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012107.1 /DEF=Homo sapiens bromodomain containing protein 75 kDa human homolog (BP75), mRNA. /FEA=mRNA /GEN=BP75 /PROD=bromodomain containing protein 75 kDa humanhomolog /DB_XREF=gi:6912269 /UG=Hs.258585 bromodomain containing protein 75 kDa human homolog /FL=gb:AF167351.1 gb:NM_012107.1 NM_012107 bromodomain containing 7 pseudogene 3 BRD7P3 23629 NR_002730 221094_s_at NM_018091 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018091.1 /DEF=Homo sapiens hypothetical protein FLJ10422 (FLJ10422), mRNA. /FEA=mRNA /GEN=FLJ10422 /PROD=hypothetical protein FLJ10422 /DB_XREF=gi:8922417 /UG=Hs.267905 hypothetical protein FLJ10422 /FL=gb:NM_018091.1 NM_018091 elongator acetyltransferase complex subunit 3 ELP3 55140 NM_001284220 /// NM_001284222 /// NM_001284224 /// NM_001284225 /// NM_001284226 /// NM_018091 /// XM_006716354 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 221095_s_at NM_005136 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005136.1 /DEF=Homo sapiens potassium voltage-gated channel, Isk-related family, member 2 (KCNE2), mRNA. /FEA=mRNA /GEN=KCNE2 /PROD=potassium voltage-gated channel, Isk-relatedfamily, member 2 /DB_XREF=gi:4826795 /UG=Hs.268538 potassium voltage-gated channel, Isk-related family, member 2 /FL=gb:AF071002.1 gb:NM_005136.1 NM_005136 potassium voltage-gated channel, Isk-related family, member 2 KCNE2 9992 NM_172201 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010107 // potassium ion import // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086009 // membrane repolarization // inferred from direct assay /// 0086011 // membrane repolarization during action potential // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 1901379 // regulation of potassium ion transmembrane transport // inferred from direct assay /// 1901800 // positive regulation of proteasomal protein catabolic process // inferred from direct assay /// 1901979 // regulation of inward rectifier potassium channel activity // inferred from direct assay /// 1902159 // regulation of cyclic nucleotide-gated ion channel activity // inferred from electronic annotation /// 1902259 // regulation of delayed rectifier potassium channel activity // inferred from direct assay /// 2001257 // regulation of cation channel activity // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005251 // delayed rectifier potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from direct assay /// 1902282 // voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization // inferred from mutant phenotype 221096_s_at NM_018502 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018502.1 /DEF=Homo sapiens hypothetical protein PRO1580 (PRO1580), mRNA. /FEA=mRNA /GEN=PRO1580 /PROD=hypothetical protein PRO1580 /DB_XREF=gi:8924057 /UG=Hs.270863 hypothetical protein PRO1580 /FL=gb:AF119848.1 gb:NM_018502.1 NM_018502 transmembrane and coiled-coil domains 6 TMCO6 55374 NM_018502 /// XM_005268476 /// XM_005268477 0006606 // protein import into nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 221097_s_at NM_005832 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005832.1 /DEF=Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2), mRNA. /FEA=mRNA /GEN=KCNMB2 /PROD=potassium large conductance calcium-activatedchannel, subfamily M, beta member 2 /DB_XREF=gi:5031822 /UG=Hs.271401 potassium large conductance calcium-activated channel, subfamily M, beta member 2 /FL=gb:AF099137.1 gb:NM_005832.1 NM_005832 potassium large conductance calcium-activated channel, subfamily M, beta member 2 KCNMB2 10242 NM_001278911 /// NM_005832 /// NM_181361 0001508 // action potential // inferred from direct assay /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019228 // neuronal action potential // inferred from direct assay /// 0019229 // regulation of vasoconstriction // traceable author statement /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008200 // ion channel inhibitor activity // traceable author statement /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // traceable author statement 221098_x_at NM_006649 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006649.1 /DEF=Homo sapiens serologically defined colon cancer antigen 16 (SDCCAG16), mRNA. /FEA=mRNA /GEN=SDCCAG16 /PROD=serologically defined colon cancer antigen 16 /DB_XREF=gi:5729955 /UG=Hs.271926 serologically defined colon cancer antigen 16 /FL=gb:AF039694.1 gb:NM_006649.1 NM_006649 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) UTP14A 10813 NM_001166221 /// NM_006649 /// XM_005262363 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221099_at NM_017960 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017960.1 /DEF=Homo sapiens hypothetical protein FLJ20808 (FLJ20808), mRNA. /FEA=mRNA /GEN=FLJ20808 /PROD=hypothetical protein FLJ20808 /DB_XREF=gi:8923683 /UG=Hs.272201 hypothetical protein FLJ20808 /FL=gb:NM_017960.1 NM_017960 221100_at NM_014070 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014070.1 /DEF=Homo sapiens STG protein (STG), mRNA. /FEA=mRNA /GEN=STG /PROD=STG protein /DB_XREF=gi:7662666 /UG=Hs.272214 STG protein /FL=gb:AB031481.1 gb:NM_014070.1 NM_014070 chromosome 6 open reading frame 15 C6orf15 29113 NM_014070 0030198 // extracellular matrix organization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0001968 // fibronectin binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0070052 // collagen V binding // inferred from electronic annotation 221101_at NM_017630 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017630.1 /DEF=Homo sapiens hypothetical protein FLJ20034 (FLJ20034), mRNA. /FEA=mRNA /GEN=FLJ20034 /PROD=hypothetical protein FLJ20034 /DB_XREF=gi:8923035 /UG=Hs.272223 hypothetical protein FLJ20034 /FL=gb:NM_017630.1 NM_017630 221102_s_at NM_017662 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017662.1 /DEF=Homo sapiens hypothetical protein FLJ20087 (FLJ20087), mRNA. /FEA=mRNA /GEN=FLJ20087 /PROD=hypothetical protein FLJ20087 /DB_XREF=gi:8923098 /UG=Hs.272225 hypothetical protein FLJ20087 /FL=gb:NM_017662.1 NM_017662 transient receptor potential cation channel, subfamily M, member 6 TRPM6 140803 NM_001177310 /// NM_001177311 /// NM_017662 /// XM_006716959 /// XR_242568 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221103_s_at NM_018338 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018338.1 /DEF=Homo sapiens hypothetical protein FLJ11142 (FLJ11142), mRNA. /FEA=mRNA /GEN=FLJ11142 /PROD=hypothetical protein FLJ11142 /DB_XREF=gi:8922896 /UG=Hs.272244 hypothetical protein FLJ11142 /FL=gb:NM_018338.1 NM_018338 WD repeat domain 52 WDR52 55779 NM_001164496 /// NM_018338 /// XM_005247617 /// XM_006713696 /// XM_006713697 /// XM_006713698 /// XM_006713699 /// XR_427370 /// XR_427371 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221104_s_at NM_018376 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018376.1 /DEF=Homo sapiens hypothetical protein FLJ11275 (FLJ11275), mRNA. /FEA=mRNA /GEN=FLJ11275 /PROD=hypothetical protein FLJ11275 /DB_XREF=gi:8922969 /UG=Hs.272248 hypothetical protein FLJ11275 /FL=gb:NM_018376.1 NM_018376 nipsnap homolog 3B (C. elegans) NIPSNAP3B 55335 NM_018376 /// XR_428532 221105_at NM_018395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018395.1 /DEF=Homo sapiens hypothetical protein FLJ11348 (FLJ11348), mRNA. /FEA=mRNA /GEN=FLJ11348 /PROD=hypothetical protein FLJ11348 /DB_XREF=gi:8923002 /UG=Hs.272252 hypothetical protein FLJ11348 /FL=gb:NM_018395.1 NM_018395 221106_at NM_016609 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016609.1 /DEF=Homo sapiens hBOIT for potent brain type organic ion transporter (LOC51310), mRNA. /FEA=mRNA /GEN=LOC51310 /PROD=hBOIT for potent brain type organic iontransporter /DB_XREF=gi:7706145 /UG=Hs.272260 hBOIT for potent brain type organic ion transporter /FL=gb:AB040056.1 gb:NM_016609.1 NM_016609 solute carrier family 22, member 17 SLC22A17 51310 NM_001289050 /// NM_016609 /// NM_020372 /// NR_110290 /// XM_005267747 /// XM_005267748 /// XR_245694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0015891 // siderophore transport // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031301 // integral component of organelle membrane // inferred from direct assay 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 221107_at NM_017581 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017581.1 /DEF=Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 9 (CHRNA9), mRNA. /FEA=mRNA /GEN=CHRNA9 /PROD=cholinergic receptor, nicotinic, alphapolypeptide 9 /DB_XREF=gi:8923741 /UG=Hs.272278 cholinergic receptor, nicotinic, alpha polypeptide 9 /FL=gb:NM_017581.1 NM_017581 cholinergic receptor, nicotinic, alpha 9 (neuronal) CHRNA9 55584 NM_017581 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from genetic interaction /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221108_at NM_016449 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016449.1 /DEF=Homo sapiens hypothetical protein (LOC51233), mRNA. /FEA=mRNA /GEN=LOC51233 /PROD=hypothetical protein /DB_XREF=gi:7705994 /UG=Hs.272302 hypothetical protein /FL=gb:AL080197.1 gb:NM_016449.1 NM_016449 aspartate-rich 1 DRICH1 51233 NM_016449 /// XM_005261624 /// XM_006724259 /// XR_430407 /// XR_430408 221109_at NM_017598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017598.1 /DEF=Homo sapiens hypothetical protein DKFZp434C0923 (DKFZp434C0923), mRNA. /FEA=mRNA /GEN=DKFZp434C0923 /PROD=hypothetical protein DKFZp434C0923 /DB_XREF=gi:8922127 /UG=Hs.272326 hypothetical protein DKFZp434C0923 /FL=gb:NM_017598.1 NM_017598 uncharacterized LOC100506571 LOC100506571 100506571 XM_003119160 /// XM_003119777 /// XM_003960276 221110_x_at NM_016953 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016953.1 /DEF=Homo sapiens phosphodiesterase 11A (PDE11A), mRNA. /FEA=mRNA /GEN=PDE11A /PROD=phosphodiesterase 11A /DB_XREF=gi:8393925 /UG=Hs.272345 phosphodiesterase 11A /FL=gb:NM_016953.1 NM_016953 phosphodiesterase 11A PDE11A 50940 NM_001077196 /// NM_001077197 /// NM_001077358 /// NM_016953 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0030553 // cGMP binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation 221111_at NM_018402 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018402.1 /DEF=Homo sapiens AK155 protein (AK155 gene) (HSA251549), mRNA. /FEA=mRNA /GEN=HSA251549 /PROD=AK155 protein (AK155 gene) /DB_XREF=gi:8923755 /UG=Hs.272350 AK155 protein (AK155 gene) /FL=gb:NM_018402.1 NM_018402 interleukin 26 IL26 55801 NM_018402 0007267 // cell-cell signaling // traceable author statement /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005125 // cytokine activity // inferred from direct assay 221112_at NM_017416 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017416.1 /DEF=Homo sapiens interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), mRNA. /FEA=mRNA /GEN=IL1RAPL2 /PROD=interleukin 1 receptor accessory protein-like 2 /DB_XREF=gi:11225606 /UG=Hs.272354 interleukin 1 receptor accessory protein-like 2 /FL=gb:AF284436.1 gb:NM_017416.1 gb:AF212016.1 NM_017416 interleukin 1 receptor accessory protein-like 2 IL1RAPL2 26280 NM_017416 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004908 // interleukin-1 receptor activity // traceable author statement /// 0004910 // interleukin-1, Type II, blocking receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221113_s_at NM_016087 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016087.1 /DEF=Homo sapiens WNT16 protein (WNT16), mRNA. /FEA=mRNA /GEN=WNT16 /PROD=WNT16 protein /DB_XREF=gi:7706772 /UG=Hs.272375 WNT16 protein /FL=gb:AF152584.1 gb:NM_016087.1 NM_016087 wingless-type MMTV integration site family, member 16 WNT16 51384 NM_016087 /// NM_057168 0003408 // optic cup formation involved in camera-type eye development // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0043616 // keratinocyte proliferation // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded 221114_at NM_016519 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016519.2 /DEF=Homo sapiens ameloblastin, enamel matrix protein (AMBN), mRNA. /FEA=mRNA /GEN=AMBN /PROD=ameloblastin /DB_XREF=gi:9665251 /UG=Hs.272396 ameloblastin, enamel matrix protein /FL=gb:AF209780.1 gb:AF219994.2 gb:AF263464.1 gb:NM_016519.2 NM_016519 ameloblastin (enamel matrix protein) AMBN 258 NM_016519 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0030282 // bone mineralization // non-traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0008083 // growth factor activity // inferred from sequence or structural similarity /// 0030345 // structural constituent of tooth enamel // inferred from electronic annotation 221115_s_at NM_018655 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018655.1 /DEF=Homo sapiens lens epithelial protein (LEP503), mRNA. /FEA=mRNA /GEN=LEP503 /PROD=lens epithelial protein /DB_XREF=gi:8923829 /UG=Hs.272399 lens epithelial protein /FL=gb:AF268478.1 gb:NM_018655.1 NM_018655 lens epithelial protein LENEP 55891 NM_018655 0007275 // multicellular organismal development // inferred from electronic annotation 0003677 // DNA binding // traceable author statement 221116_at NM_016566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016566.1 /DEF=Homo sapiens pparl (LOC51288), mRNA. /FEA=mRNA /GEN=LOC51288 /PROD=pparl /DB_XREF=gi:7706100 /UG=Hs.272401 pparl /FL=gb:AF242527.1 gb:NM_016566.1 NM_016566 221117_at NM_016637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016637.1 /DEF=Homo sapiens ncaml (LOC51328), mRNA. /FEA=mRNA /GEN=LOC51328 /PROD=ncaml /DB_XREF=gi:7706181 /UG=Hs.272413 ncaml /FL=gb:AF241539.1 gb:NM_016637.1 NM_016637 221118_at NM_014386 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014386.1 /DEF=Homo sapiens polycystic kidney disease 2-like 2 (PKD2L2), mRNA. /FEA=mRNA /GEN=PKD2L2 /PROD=polycystic kidney disease 2-like 2 /DB_XREF=gi:7657458 /UG=Hs.272418 polycystic kidney disease 2-like 2 /FL=gb:AF118125.1 gb:NM_014386.1 NM_014386 polycystic kidney disease 2-like 2 PKD2L2 27039 NM_001258448 /// NM_001258449 /// NM_014386 /// XM_005271960 /// XM_006714586 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // not recorded /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // not recorded 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005216 // ion channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation 221119_at NM_017700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017700.1 /DEF=Homo sapiens hypothetical protein FLJ20184 (FLJ20184), mRNA. /FEA=mRNA /GEN=FLJ20184 /PROD=hypothetical protein FLJ20184 /DB_XREF=gi:8923172 /UG=Hs.272787 hypothetical protein FLJ20184 /FL=gb:NM_017700.1 NM_017700 Rho guanine nucleotide exchange factor (GEF) 38 ARHGEF38 54848 NM_001242729 /// NM_017700 /// XM_006714244 /// XR_427548 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 221120_at NM_017756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017756.1 /DEF=Homo sapiens hypothetical protein FLJ20306 (FLJ20306), mRNA. /FEA=mRNA /GEN=FLJ20306 /PROD=hypothetical protein FLJ20306 /DB_XREF=gi:8923286 /UG=Hs.272791 hypothetical protein FLJ20306 /FL=gb:NM_017756.1 NM_017756 221121_at NM_017863 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017863.1 /DEF=Homo sapiens hypothetical protein FLJ20527 (FLJ20527), mRNA. /FEA=mRNA /GEN=FLJ20527 /PROD=hypothetical protein FLJ20527 /DB_XREF=gi:8923492 /UG=Hs.272804 hypothetical protein FLJ20527 /FL=gb:NM_017863.1 NM_017863 cancer/testis antigen 55 CT55 54967 NM_001031705 /// NM_017863 /// XM_005262427 221122_at NM_017878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017878.1 /DEF=Homo sapiens hypothetical protein FLJ20556 (FLJ20556), mRNA. /FEA=mRNA /GEN=FLJ20556 /PROD=hypothetical protein FLJ20556 /DB_XREF=gi:8923525 /UG=Hs.272805 hypothetical protein FLJ20556 /FL=gb:NM_017878.1 NM_017878 HRAS-like suppressor 2 HRASLS2 54979 NM_017878 0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221123_x_at NM_018660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018660.1 /DEF=Homo sapiens papillomavirus regulatory factor PRF-1 (LOC55893), mRNA. /FEA=mRNA /GEN=LOC55893 /PROD=papillomavirus regulatory factor PRF-1 /DB_XREF=gi:8923886 /UG=Hs.27410 papillomavirus regulatory factor PRF-1 /FL=gb:AF263928.1 gb:NM_018660.1 NM_018660 F-box protein 16 /// zinc finger protein 395 FBXO16 /// ZNF395 55893 /// 157574 NM_001258211 /// NM_018660 /// NM_172366 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221124_s_at NM_014588 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014588.2 /DEF=Homo sapiens visual system homeobox 1 (zebrafish) homolog (CHX10-like) (VSX1), mRNA. /FEA=mRNA /GEN=VSX1 /PROD=visual system homeobox 1 (zebrafish) homolog(CHX10-like) /DB_XREF=gi:11056037 /UG=Hs.274264 visual system homeobox 1 (zebrafish) homolog (CHX10-like) /FL=gb:AF176797.2 gb:NM_014588.2 gb:AF251033.1 NM_014588 visual system homeobox 1 VSX1 30813 NM_001256271 /// NM_001256272 /// NM_014588 /// NM_199425 /// NR_045948 /// NR_045951 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060040 // retinal bipolar neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221125_s_at NM_014407 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014407.1 /DEF=Homo sapiens potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), mRNA. /FEA=mRNA /GEN=KCNMB3 /PROD=potassium large conductance calcium-activatedchannel, subfamily M beta member 3 /DB_XREF=gi:7657250 /UG=Hs.276973 potassium large conductance calcium-activated channel, subfamily M beta member 3 /FL=gb:AF139471.1 gb:NM_014407.1 NM_014407 potassium large conductance calcium-activated channel, subfamily M beta member 3 KCNMB3 27094 NM_001163677 /// NM_014407 /// NM_171828 /// NM_171829 /// NM_171830 /// NR_028135 0001508 // action potential // inferred from direct assay /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019228 // neuronal action potential // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement 221126_at NM_006394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006394.1 /DEF=Homo sapiens regulated in glioma (RIG), mRNA. /FEA=mRNA /GEN=RIG /PROD=regulated in glioma /DB_XREF=gi:5454007 /UG=Hs.278503 regulated in glioma /FL=gb:NM_006394.1 gb:U32331.1 NM_006394 dickkopf WNT signaling pathway inhibitor 3 DKK3 27122 NM_001018057 /// NM_013253 /// NM_015881 /// XM_006718177 /// XM_006718178 /// XM_006718179 /// XM_006718180 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from expression pattern /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 221127_s_at NM_006394 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006394.1 /DEF=Homo sapiens regulated in glioma (RIG), mRNA. /FEA=mRNA /GEN=RIG /PROD=regulated in glioma /DB_XREF=gi:5454007 /UG=Hs.278503 regulated in glioma /FL=gb:NM_006394.1 gb:U32331.1 NM_006394 dickkopf WNT signaling pathway inhibitor 3 DKK3 27122 NM_001018057 /// NM_013253 /// NM_015881 /// XM_006718177 /// XM_006718178 /// XM_006718179 /// XM_006718180 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from expression pattern /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 221128_at NM_023038 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023038.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 19 (meltrin beta) (ADAM19), mRNA. /FEA=mRNA /GEN=ADAM19 /PROD=a disintegrin and metalloproteinase domain 19(meltrin beta) /DB_XREF=gi:12738835 /UG=Hs.278679 a disintegrin and metalloproteinase domain 19 (meltrin beta) /FL=gb:AF326918.1 gb:NM_023038.1 NM_023038 ADAM metallopeptidase domain 19 ADAM19 8728 NM_023038 /// NM_033274 /// XM_005266003 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221129_at NM_014318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014318.1 /DEF=Homo sapiens apoptosis related protein (APR-2), mRNA. /FEA=mRNA /GEN=APR-2 /PROD=apoptosis related protein /DB_XREF=gi:7656895 /UG=Hs.278902 apoptosis related protein /FL=gb:AF143236.1 gb:NM_014318.1 NM_014318 family with sequence similarity 215, member A (non-protein coding) FAM215A 23591 NR_026770 0006915 // apoptotic process // inferred from electronic annotation 221130_s_at NM_014113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014113.1 /DEF=Homo sapiens PRO0038 protein (PRO0038), mRNA. /FEA=mRNA /GEN=PRO0038 /PROD=PRO0038 protein /DB_XREF=gi:7662519 /UG=Hs.278927 PRO0038 protein /FL=gb:AF090884.1 gb:NM_014113.1 NM_014113 221131_at NM_016161 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016161.1 /DEF=Homo sapiens alpha-1,4-N-acetylglucosaminyltransferase (LOC51146), mRNA. /FEA=mRNA /GEN=LOC51146 /PROD=alpha-1,4-N-acetylglucosaminyltransferase /DB_XREF=gi:7705858 /UG=Hs.278960 alpha-1,4-N-acetylglucosaminyltransferase /FL=gb:AF141315.1 gb:NM_016161.1 NM_016161 alpha-1,4-N-acetylglucosaminyltransferase A4GNT 51146 NM_016161 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 221132_at NM_016369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016369.1 /DEF=Homo sapiens claudin 18 (CLDN18), mRNA. /FEA=mRNA /GEN=CLDN18 /PROD=claudin 18 /DB_XREF=gi:7705960 /UG=Hs.278966 Claudin-18 /FL=gb:AF221069.1 gb:NM_016369.1 NM_016369 claudin 18 CLDN18 51208 NM_001002026 /// NM_016369 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 221133_s_at NM_016369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016369.1 /DEF=Homo sapiens claudin 18 (CLDN18), mRNA. /FEA=mRNA /GEN=CLDN18 /PROD=claudin 18 /DB_XREF=gi:7705960 /UG=Hs.278966 Claudin-18 /FL=gb:AF221069.1 gb:NM_016369.1 NM_016369 claudin 18 CLDN18 51208 NM_001002026 /// NM_016369 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 221134_at NM_015985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015985.1 /DEF=Homo sapiens angiopoietin-3 (ANG-3), mRNA. /FEA=mRNA /GEN=ANG-3 /PROD=angiopoietin-3 /DB_XREF=gi:7705275 /UG=Hs.278973 angiopoietin-3 /FL=gb:AF074332.1 gb:NM_015985.1 NM_015985 angiopoietin 4 ANGPT4 51378 NM_015985 /// XM_005260720 /// XM_006723567 0001525 // angiogenesis // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0007171 // activation of transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0030297 // transmembrane receptor protein tyrosine kinase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay 221135_s_at NM_014065 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014065.1 /DEF=Homo sapiens HT001 protein (HT001), mRNA. /FEA=mRNA /GEN=HT001 /PROD=HT001 protein /DB_XREF=gi:7661837 /UG=Hs.279040 HT001 protein /FL=gb:AF113539.1 gb:NM_014065.1 NM_014065 asteroid homolog 1 (Drosophila) ASTE1 28990 NM_001288950 /// NM_014065 /// NR_110229 /// XM_006713609 0006281 // DNA repair // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation 221136_at NM_016204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016204.1 /DEF=Homo sapiens growth differentiation factor 2 (GDF2), mRNA. /FEA=mRNA /GEN=GDF2 /PROD=growth differentiation factor 2 /DB_XREF=gi:7705307 /UG=Hs.279463 growth differentiation factor 2 /FL=gb:AF188285.1 gb:NM_016204.1 NM_016204 growth differentiation factor 2 GDF2 2658 NM_016204 /// XM_006717761 0001503 // ossification // traceable author statement /// 0001525 // angiogenesis // inferred from mutant phenotype /// 0001569 // patterning of blood vessels // inferred from direct assay /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from direct assay /// 0051216 // cartilage development // traceable author statement /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 2000279 // negative regulation of DNA biosynthetic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 221137_at AF118071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF118071.1 /DEF=Homo sapiens PRO1693 mRNA, complete cds. /FEA=mRNA /PROD=PRO1693 /DB_XREF=gi:6650787 /UG=Hs.279778 PRO1693 protein /FL=gb:AF118071.1 gb:NM_014097.1 AF118071 221138_s_at NM_014097 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014097.1 /DEF=Homo sapiens PRO1693 protein (PRO1693), mRNA. /FEA=mRNA /GEN=PRO1693 /PROD=PRO1693 protein /DB_XREF=gi:7662605 /UG=Hs.279778 PRO1693 protein /FL=gb:AF118071.1 gb:NM_014097.1 NM_014097 221139_s_at NM_015989 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015989.1 /DEF=Homo sapiens cysteine sulfinic acid decarboxylase-relatedprotein 2 (CSAD), mRNA. /FEA=mRNA /GEN=CSAD /PROD=cysteine sulfinic aciddecarboxylase-relatedprotein 2 /DB_XREF=gi:7705333 /UG=Hs.279815 cysteine sulfinic acid decarboxylase-relatedprotein 2 /FL=gb:AF116546.1 gb:NM_015989.1 NM_015989 cysteine sulfinic acid decarboxylase CSAD 51380 NM_001244705 /// NM_001244706 /// NM_015989 /// XM_005268951 /// XM_005268954 /// XM_005268955 /// XM_006719447 /// XM_006719448 /// XR_245935 /// XR_245936 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019752 // carboxylic acid metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042412 // taurine biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004782 // sulfinoalanine decarboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 221140_s_at NM_013345 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013345.1 /DEF=Homo sapiens G protein-coupled receptor (G2A), mRNA. /FEA=mRNA /GEN=G2A /PROD=G protein-coupled receptor /DB_XREF=gi:7019386 /UG=Hs.279852 G protein-coupled receptor /FL=gb:AF083955.1 gb:NM_013345.1 NM_013345 G protein-coupled receptor 132 GPR132 29933 NM_001278694 /// NM_001278695 /// NM_001278696 /// NM_013345 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221141_x_at NM_013333 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013333.1 /DEF=Homo sapiens EH domain-binding mitotic phosphoprotein (EPSIN), mRNA. /FEA=mRNA /GEN=EPSIN /PROD=EH domain-binding mitotic phosphoprotein /DB_XREF=gi:7019368 /UG=Hs.279953 EH domain-binding mitotic phosphoprotein /FL=gb:AF073727.1 gb:NM_013333.1 NM_013333 epsin 1 EPN1 29924 NM_001130071 /// NM_001130072 /// NM_013333 /// XM_005258829 /// XM_005258830 /// XM_006723176 /// XM_006723177 /// XM_006723178 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 221142_s_at NM_018441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018441.1 /DEF=Homo sapiens peroxisomal trans 2-enoyl CoA reductase; putative short chain alcohol dehydrogenase (HSA250303), mRNA. /FEA=mRNA /GEN=HSA250303 /PROD=peroxisomal trans 2-enoyl CoA reductase;putative short chain alcohol dehydrogenase /DB_XREF=gi:8923751 /UG=Hs.281680 peroxisomal trans 2-enoyl CoA reductase; putative short chain alcohol dehydrogenase /FL=gb:NM_018441.1 NM_018441 peroxisomal trans-2-enoyl-CoA reductase PECR 55825 NM_018441 /// XR_427102 /// XR_427103 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033306 // phytol metabolic process // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0008670 // 2,4-dienoyl-CoA reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019166 // trans-2-enoyl-CoA reductase (NADPH) activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 221143_at NM_013347 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013347.1 /DEF=Homo sapiens replication protein A complex 34 kd subunit homolog Rpa4 (HSU24186), mRNA. /FEA=mRNA /GEN=HSU24186 /PROD=replication protein A complex 34 kd subunithomolog Rpa4 /DB_XREF=gi:9558730 /UG=Hs.283018 replication protein A complex 34 kd subunit homolog Rpa4 /FL=gb:U24186.2 gb:NM_013347.1 NM_013347 replication protein A4, 30kDa RPA4 29935 NM_013347 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006270 // DNA replication initiation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0033260 // nuclear cell cycle DNA replication // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement 221144_at NM_018497 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018497.1 /DEF=Homo sapiens hypothetical protein PRO1048 (PRO1048), mRNA. /FEA=mRNA /GEN=PRO1048 /PROD=hypothetical protein PRO1048 /DB_XREF=gi:8924002 /UG=Hs.283026 hypothetical protein PRO1048 /FL=gb:AF119842.1 gb:NM_018497.1 NM_018497 221145_at NM_018499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018499.1 /DEF=Homo sapiens hypothetical protein PRO1097 (PRO1097), mRNA. /FEA=mRNA /GEN=PRO1097 /PROD=hypothetical protein PRO1097 /DB_XREF=gi:8924017 /UG=Hs.283027 hypothetical protein PRO1097 /FL=gb:AF119844.1 gb:NM_018499.1 NM_018499 221146_at NM_018532 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018532.1 /DEF=Homo sapiens hypothetical protein PRO2610 (PRO2610), mRNA. /FEA=mRNA /GEN=PRO2610 /PROD=hypothetical protein PRO2610 /DB_XREF=gi:8924185 /UG=Hs.283041 hypothetical protein PRO2610 /FL=gb:AF119887.1 gb:NM_018532.1 NM_018532 221147_x_at NM_018560 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018560.2 /DEF=Homo sapiens WW domain-containing oxidoreductase (WWOX), mRNA. /FEA=mRNA /GEN=WWOX /PROD=hypothetical protein PRO0128 /DB_XREF=gi:13699257 /UG=Hs.283048 hypothetical protein PRO0128 /FL=gb:NM_018560.2 NM_018560 WW domain containing oxidoreductase WWOX 51741 NM_001291997 /// NM_016373 /// NM_018560 /// NM_130788 /// NM_130790 /// NM_130791 /// NM_130792 /// NM_130844 /// NR_120435 /// NR_120436 /// XM_006721195 /// XR_243411 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0046983 // protein dimerization activity // traceable author statement /// 0048037 // cofactor binding // traceable author statement /// 0050662 // coenzyme binding // traceable author statement 221148_at NM_018625 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018625.1 /DEF=Homo sapiens hypothetical protein PRO2289 (PRO2289), mRNA. /FEA=mRNA /GEN=PRO2289 /PROD=hypothetical protein PRO2289 /DB_XREF=gi:8924150 /UG=Hs.283069 hypothetical protein PRO2289 /FL=gb:AF116698.1 gb:NM_018625.1 NM_018625 RP11-457I16.2 221149_at NM_018485 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018485.1 /DEF=Homo sapiens G protein-coupled receptor C5L2 (LOC55868), mRNA. /FEA=mRNA /GEN=LOC55868 /PROD=G protein-coupled receptor C5L2 /DB_XREF=gi:8923872 /UG=Hs.283079 G protein-coupled receptor C5L2 /FL=gb:AB038237.1 gb:NM_018485.1 NM_018485 complement component 5a receptor 2 C5AR2 27202 NM_001271749 /// NM_001271750 /// NM_018485 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0090024 // negative regulation of neutrophil chemotaxis // inferred from mutant phenotype /// 1900165 // negative regulation of interleukin-6 secretion // inferred from mutant phenotype /// 2000482 // regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004944 // C5a anaphylatoxin receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221150_at NM_020203 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020203.1 /DEF=Homo sapiens matrix, extracellular phosphoglycoprotein with ASARM motif (bone) (MEPE), mRNA. /FEA=mRNA /GEN=MEPE /PROD=matrix, extracellular phosphoglycoprotein withASARM motif (bone) /DB_XREF=gi:9910429 /UG=Hs.283095 matrix, extracellular phosphoglycoprotein with ASARM motif (bone) /FL=gb:NM_020203.1 NM_020203 matrix extracellular phosphoglycoprotein MEPE 56955 NM_001184694 /// NM_001184695 /// NM_001184696 /// NM_001184697 /// NM_001291183 /// NM_020203 /// XM_006714278 0001501 // skeletal system development // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0046850 // regulation of bone remodeling // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221151_at NM_020227 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020227.1 /DEF=Homo sapiens PR domain containing 9 (PRDM9), mRNA. /FEA=mRNA /GEN=PRDM9 /PROD=PR domain containing 9 /DB_XREF=gi:9910509 /UG=Hs.283096 PR domain containing 9 /FL=gb:AF275816.1 gb:NM_020227.1 NM_020227 PR domain containing 9 PRDM9 56979 NM_020227 0006311 // meiotic gene conversion // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0010844 // recombination hotspot binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221152_at NM_020351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020351.1 /DEF=Homo sapiens smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 (LOC57086), mRNA. /FEA=mRNA /GEN=LOC57086 /PROD=smooth muscle cell-expressed and macrophageconditioned medium-induced protein smag-64 /DB_XREF=gi:9966814 /UG=Hs.283100 smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 /FL=gb:AF170702.1 gb:NM_020351.1 NM_020351 collagen, type VIII, alpha 1 COL8A1 1295 NM_001850 /// NM_020351 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005591 // collagen type VIII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221153_s_at NM_020355 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020355.1 /DEF=Homo sapiens HRPAP20 short form (LOC57090), mRNA. /FEA=mRNA /GEN=LOC57090 /PROD=HRPAP20 short form /DB_XREF=gi:9966822 /UG=Hs.283101 HRPAP20 short form /FL=gb:AF283900.1 gb:NM_020355.1 NM_020355 221154_at NM_020358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020358.1 /DEF=Homo sapiens ring finger protein 18 (RNF18), mRNA. /FEA=mRNA /GEN=RNF18 /PROD=ring finger protein 18 /DB_XREF=gi:9966828 /UG=Hs.283103 ring finger protein 18 /FL=gb:AB037682.1 gb:NM_020358.1 NM_020358 tripartite motif containing 49 /// tripartite motif containing 49C TRIM49 /// TRIM49C 57093 /// 642612 NM_001195234 /// NM_020358 0005622 // intracellular // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221155_x_at NM_018603 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018603.1 /DEF=Homo sapiens hypothetical protein PRO1496 (PRO1496), mRNA. /FEA=mRNA /GEN=PRO1496 /PROD=hypothetical protein PRO1496 /DB_XREF=gi:8924053 /UG=Hs.283617 hypothetical protein PRO1496 /FL=gb:AF116665.1 gb:NM_018603.1 NM_018603 221156_x_at NM_004748 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004748.1 /DEF=Homo sapiens cell cycle progression 8 protein (CPR8), mRNA. /FEA=mRNA /GEN=CPR8 /PROD=cell cycle progression 8 protein /DB_XREF=gi:4758047 /UG=Hs.283753 cell cycle progression 8 protein /FL=gb:AF011794.1 gb:NM_004748.1 NM_004748 cell cycle progression 1 CCPG1 9236 NM_001204450 /// NM_001204451 /// NM_004748 /// NM_020739 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001106 // regulation of Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221157_s_at NM_012172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012172.1 /DEF=Homo sapiens F-box only protein 24 (FBXO24), mRNA. /FEA=mRNA /GEN=FBXO24 /PROD=F-box only protein 24 /DB_XREF=gi:11024695 /UG=Hs.283764 F-box only protein 24 /FL=gb:NM_012172.1 NM_012172 F-box protein 24 FBXO24 26261 NM_001163499 /// NM_012172 /// NM_033506 /// XM_005250259 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221158_at NM_013329 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013329.1 /DEF=Homo sapiens GC-rich sequence DNA-binding factor candidate (GCFC), mRNA. /FEA=mRNA /GEN=GCFC /PROD=GC-rich sequence DNA-binding factor candidate /DB_XREF=gi:7019390 /UG=Hs.283771 GC-rich sequence DNA-binding factor candidate /FL=gb:AF153208.1 gb:NM_013329.1 NM_013329 PAX3 and PAX7 binding protein 1 PAXBP1 94104 NM_013329 /// NM_016631 /// NM_058191 /// NM_145328 /// NR_027873 /// XM_006724066 /// XM_006724067 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007517 // muscle organ development // inferred from electronic annotation /// 0014842 // regulation of satellite cell proliferation // inferred from electronic annotation /// 0031062 // positive regulation of histone methylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2000288 // positive regulation of myoblast proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation 221159_at NM_016414 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016414.1 /DEF=Homo sapiens clone FLB1727 (LOC51215), mRNA. /FEA=mRNA /GEN=LOC51215 /PROD=clone FLB1727 /DB_XREF=gi:10092634 /UG=Hs.283773 clone FLB1727 /FL=gb:NM_016414.1 gb:AF113674.1 NM_016414 221160_s_at NM_019855 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019855.1 /DEF=Homo sapiens calcium binding protein 5 (CABP5), mRNA. /FEA=mRNA /GEN=CABP5 /PROD=calcium binding protein 5 /DB_XREF=gi:11067752 /UG=Hs.283804 calcium binding protein 5 /FL=gb:NM_019855.1 gb:AF169159.1 NM_019855 calcium binding protein 5 CABP5 56344 NM_016367 /// NM_019855 0007165 // signal transduction // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221161_at NM_020646 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020646.1 /DEF=Homo sapiens reserved (ASCL3), mRNA. /FEA=mRNA /GEN=ASCL3 /PROD=reserved /DB_XREF=gi:10190679 /UG=Hs.283808 reserved /FL=gb:NM_020646.1 NM_020646 achaete-scute family bHLH transcription factor 3 ASCL3 56676 NM_020646 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 221162_at NM_005712 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005712.1 /DEF=Homo sapiens HERV-H LTR-associating 1 (HHLA1), mRNA. /FEA=mRNA /GEN=HHLA1 /PROD=HERV-H LTR-associating 1 /DB_XREF=gi:5031738 /UG=Hs.285026 HERV-H LTR-associating 1 /FL=gb:AF110315.1 gb:NM_005712.1 NM_005712 HERV-H LTR-associating 1 HHLA1 10086 NM_001145095 /// NM_005712 0005576 // extracellular region // inferred from electronic annotation 221163_s_at NM_015977 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015977.1 /DEF=Homo sapiens Williams-Beuren syndrome chromosome region 14 (WBSCR14), mRNA. /FEA=mRNA /GEN=WBSCR14 /PROD=WBSCR14 protein /DB_XREF=gi:7705745 /UG=Hs.285681 Williams-Beuren syndrome chromosome region 14 /FL=gb:AF056184.1 gb:NM_015977.1 NM_015977 MLX interacting protein-like MLXIPL 51085 NM_032951 /// NM_032952 /// NM_032953 /// NM_032954 /// NM_032994 /// XM_005250399 /// XM_006716016 /// XM_006716017 /// XM_006716018 /// XM_006716019 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010255 // glucose mediated signaling pathway // inferred from sequence or structural similarity /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from mutant phenotype /// 0055089 // fatty acid homeostasis // inferred from sequence or structural similarity /// 0070328 // triglyceride homeostasis // non-traceable author statement /// 0071157 // negative regulation of cell cycle arrest // inferred from mutant phenotype /// 0090324 // negative regulation of oxidative phosphorylation // inferred from mutant phenotype /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // non-traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035538 // carbohydrate response element binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 221164_x_at NM_012126 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012126.1 /DEF=Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 (CHST5), mRNA. /FEA=mRNA /GEN=CHST5 /PROD=carbohydrate (N-acetylglucosamine 6-O)sulfotransferase 5 /DB_XREF=gi:6912305 /UG=Hs.287366 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 /FL=gb:AF176838.1 gb:NM_012126.1 NM_012126 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 CHST5 23563 NM_012126 /// NM_024533 0005975 // carbohydrate metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006477 // protein sulfation // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0031228 // intrinsic component of Golgi membrane // non-traceable author statement 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 221165_s_at NM_020525 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020525.1 /DEF=Homo sapiens interleukin 22 (IL22), mRNA. /FEA=mRNA /GEN=IL22 /PROD=IL-10-related T-cell-derived inducible factor /DB_XREF=gi:10092624 /UG=Hs.287369 interleukin 22 /FL=gb:NM_020525.1 gb:AF279437.1 NM_020525 interleukin 22 IL22 50616 NM_020525 /// XM_005268929 0006953 // acute-phase response // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0007267 // cell-cell signaling // inferred by curator /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred by curator /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0045518 // interleukin-22 receptor binding // non-traceable author statement 221166_at NM_020638 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020638.1 /DEF=Homo sapiens fibroblast growth factor 23 (FGF23), mRNA. /FEA=mRNA /GEN=FGF23 /PROD=fibroblast growth factor 23 /DB_XREF=gi:10190673 /UG=Hs.287370 fibroblast growth factor 23 /FL=gb:AB037973.1 gb:NM_020638.1 gb:AF263537.1 NM_020638 fibroblast growth factor 23 FGF23 8074 NM_020638 0006796 // phosphate-containing compound metabolic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010966 // regulation of phosphate transport // inferred from direct assay /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0030643 // cellular phosphate ion homeostasis // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042359 // vitamin D metabolic process // inferred from electronic annotation /// 0042369 // vitamin D catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046888 // negative regulation of hormone secretion // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0055062 // phosphate ion homeostasis // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221167_s_at NM_031290 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031290.1 /DEF=Homo sapiens hypothetical protein DKFZp434K1172 (DKFZP434K1172), mRNA. /FEA=mRNA /GEN=DKFZP434K1172 /PROD=hypothetical protein DKFZp434K1172 /DB_XREF=gi:13775205 /FL=gb:NM_031290.1 NM_031290 coiled-coil domain containing 70 CCDC70 83446 NM_031290 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 221168_at NM_021620 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021620.1 /DEF=Homo sapiens PR domain containing 13 (PRDM13), mRNA. /FEA=mRNA /GEN=PRDM13 /PROD=PR domain containing 13 /DB_XREF=gi:11055981 /UG=Hs.287386 PR domain containing 13 /FL=gb:AY004253.1 gb:NM_021620.1 NM_021620 PR domain containing 13 PRDM13 59336 NM_021620 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221169_s_at NM_021624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021624.1 /DEF=Homo sapiens histamine H4 receptor (HRH4), mRNA. /FEA=mRNA /GEN=HRH4 /PROD=histamine H4 receptor /DB_XREF=gi:11055987 /UG=Hs.287388 histamine H4 receptor /FL=gb:AB044934.1 gb:NM_021624.1 gb:AF307973.1 gb:AB045370.1 gb:AF312230.1 NM_021624 histamine receptor H4 HRH4 59340 NM_001143828 /// NM_001160166 /// NM_021624 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // non-traceable author statement 221170_at AF312230 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF312230.1 /DEF=Homo sapiens histamine receptor H4 subtype mRNA, complete cds. /FEA=mRNA /PROD=histamine receptor H4 subtype /DB_XREF=gi:13094918 /UG=Hs.287388 histamine H4 receptor /FL=gb:AB044934.1 gb:NM_021624.1 gb:AF307973.1 gb:AB045370.1 gb:AF312230.1 AF312230 histamine receptor H4 HRH4 59340 NM_001143828 /// NM_001160166 /// NM_021624 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // non-traceable author statement 221171_at NM_025030 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025030.1 /DEF=Homo sapiens hypothetical protein FLJ20972 (FLJ20972), mRNA. /FEA=mRNA /GEN=FLJ20972 /PROD=hypothetical protein FLJ20972 /DB_XREF=gi:13376553 /UG=Hs.287644 hypothetical protein FLJ20972 /FL=gb:NM_025030.1 NM_025030 coiled-coil domain containing 30 CCDC30 728621 NM_001080850 0070062 // extracellular vesicular exosome // inferred from direct assay 221172_at NM_025031 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025031.1 /DEF=Homo sapiens hypothetical protein FLJ21075 (FLJ21075), mRNA. /FEA=mRNA /GEN=FLJ21075 /PROD=hypothetical protein FLJ21075 /DB_XREF=gi:13376555 /UG=Hs.287647 hypothetical protein FLJ21075 /FL=gb:NM_025031.1 NM_025031 chromosome 7 open reading frame 69 C7orf69 80099 NM_025031 0005576 // extracellular region // inferred from electronic annotation 221173_at NM_025034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025034.1 /DEF=Homo sapiens hypothetical protein FLJ21290 (FLJ21290), mRNA. /FEA=mRNA /GEN=FLJ21290 /PROD=hypothetical protein FLJ21290 /DB_XREF=gi:13376561 /UG=Hs.287656 hypothetical protein FLJ21290 /FL=gb:NM_025034.1 NM_025034 Usher syndrome 1C (autosomal recessive, severe) USH1C 10083 NM_005709 /// NM_153676 /// XM_005252725 /// XM_006718119 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0030046 // parallel actin filament bundle assembly // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0032420 // stereocilium // traceable author statement /// 0045177 // apical part of cell // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 221174_at NM_025039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025039.1 /DEF=Homo sapiens hypothetical protein FLJ21625 (FLJ21625), mRNA. /FEA=mRNA /GEN=FLJ21625 /PROD=hypothetical protein FLJ21625 /DB_XREF=gi:13376563 /UG=Hs.287673 hypothetical protein FLJ21625 /FL=gb:NM_025039.1 NM_025039 221175_at NM_025041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025041.1 /DEF=Homo sapiens hypothetical protein FLJ22173 (FLJ22173), mRNA. /FEA=mRNA /GEN=FLJ22173 /PROD=hypothetical protein FLJ22173 /DB_XREF=gi:13376565 /UG=Hs.287691 hypothetical protein FLJ22173 /FL=gb:NM_025041.1 NM_025041 chromosome 3 open reading frame 36 C3orf36 80111 NM_025041 221176_x_at NM_025042 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025042.1 /DEF=Homo sapiens hypothetical protein FLJ22367 (FLJ22367), mRNA. /FEA=mRNA /GEN=FLJ22367 /PROD=hypothetical protein FLJ22367 /DB_XREF=gi:13435154 /UG=Hs.287693 hypothetical protein FLJ22367 /FL=gb:NM_025042.1 NM_025042 221177_at NM_025043 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025043.1 /DEF=Homo sapiens hypothetical protein FLJ22404 (FLJ22404), mRNA. /FEA=mRNA /GEN=FLJ22404 /PROD=hypothetical protein FLJ22404 /DB_XREF=gi:13376567 /UG=Hs.287694 hypothetical protein FLJ22404 /FL=gb:NM_025043.1 NM_025043 melanoma inhibitory activity 2 MIA2 117153 NM_054024 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0070328 // triglyceride homeostasis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221178_at NM_025045 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025045.1 /DEF=Homo sapiens hypothetical protein FLJ22582 (FLJ22582), mRNA. /FEA=mRNA /GEN=FLJ22582 /PROD=hypothetical protein FLJ22582 /DB_XREF=gi:13376571 /UG=Hs.287699 hypothetical protein FLJ22582 /FL=gb:NM_025045.1 NM_025045 BAI1-associated protein 2-like 2 BAIAP2L2 80115 NM_025045 /// XM_005261751 0007165 // signal transduction // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0061024 // membrane organization // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005543 // phospholipid binding // inferred from sequence or structural similarity /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 221179_at NM_025050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025050.1 /DEF=Homo sapiens hypothetical protein FLJ22714 (FLJ22714), mRNA. /FEA=mRNA /GEN=FLJ22714 /PROD=hypothetical protein FLJ22714 /DB_XREF=gi:13449270 /UG=Hs.287712 hypothetical protein FLJ22714 /FL=gb:NM_025050.1 NM_025050 proline rich, Y-linked PRORY 100533178 NM_001282471 221180_at NM_025052 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025052.1 /DEF=Homo sapiens hypothetical protein FLJ23074 (FLJ23074), mRNA. /FEA=mRNA /GEN=FLJ23074 /PROD=hypothetical protein FLJ23074 /DB_XREF=gi:13376581 /UG=Hs.287719 hypothetical protein FLJ23074 /FL=gb:NM_025052.1 NM_025052 mitogen-activated protein kinase kinase kinase 19 MAP3K19 80122 NM_001018044 /// NM_001018045 /// NM_001018046 /// NM_001018047 /// NM_001282883 /// NM_025052 /// XM_006712774 0000165 // MAPK cascade // not recorded /// 0000186 // activation of MAPKK activity // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // not recorded 0005737 // cytoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221181_at NM_025062 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025062.1 /DEF=Homo sapiens hypothetical protein FLJ23429 (FLJ23429), mRNA. /FEA=mRNA /GEN=FLJ23429 /PROD=hypothetical protein FLJ23429 /DB_XREF=gi:13376598 /UG=Hs.287741 hypothetical protein FLJ23429 /FL=gb:NM_025062.1 NM_025062 221182_at NM_025063 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025063.1 /DEF=Homo sapiens hypothetical protein FLJ23550 (FLJ23550), mRNA. /FEA=mRNA /GEN=FLJ23550 /PROD=hypothetical protein FLJ23550 /DB_XREF=gi:13376600 /UG=Hs.287746 hypothetical protein FLJ23550 /FL=gb:NM_025063.1 NM_025063 maestro heat-like repeat family member 9 MROH9 80133 NM_001163629 /// NM_025063 0005488 // binding // inferred from electronic annotation 221183_at NM_025064 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025064.1 /DEF=Homo sapiens hypothetical protein FLJ23604 (FLJ23604), mRNA. /FEA=mRNA /GEN=FLJ23604 /PROD=hypothetical protein FLJ23604 /DB_XREF=gi:13376602 /UG=Hs.287751 hypothetical protein FLJ23604 /FL=gb:NM_025064.1 NM_025064 uncharacterized LOC100507388 LOC100507388 100507388 NR_121617 /// XR_132696 /// XR_133370 /// XR_171456 221184_at NM_025089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025089.1 /DEF=Homo sapiens hypothetical protein FLJ23497 (FLJ23497), mRNA. /FEA=mRNA /GEN=FLJ23497 /PROD=hypothetical protein FLJ23497 /DB_XREF=gi:13376647 /UG=Hs.288498 hypothetical protein FLJ23497 /FL=gb:NM_025089.1 NM_025089 221185_s_at NM_025111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025111.1 /DEF=Homo sapiens hypothetical protein FLJ23571 (FLJ23571), mRNA. /FEA=mRNA /GEN=FLJ23571 /PROD=hypothetical protein FLJ23571 /DB_XREF=gi:13376682 /UG=Hs.288693 hypothetical protein FLJ23571 /FL=gb:NM_025111.1 NM_025111 IQ motif containing G IQCG 84223 NM_001134435 /// NM_032263 /// XM_006713784 /// XM_006713785 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221186_at NM_025116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025116.1 /DEF=Homo sapiens hypothetical protein FLJ12781 (FLJ12781), mRNA. /FEA=mRNA /GEN=FLJ12781 /PROD=hypothetical protein FLJ12781 /DB_XREF=gi:13376692 /UG=Hs.288726 hypothetical protein FLJ12781 /FL=gb:NM_025116.1 NM_025116 uncharacterized LOC100131532 LOC100131532 100131532 NR_027434 221187_s_at NM_025129 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025129.1 /DEF=Homo sapiens hypothetical protein FLJ22688 (FLJ22688), mRNA. /FEA=mRNA /GEN=FLJ22688 /PROD=hypothetical protein FLJ22688 /DB_XREF=gi:13376708 /UG=Hs.288800 hypothetical protein FLJ22688 /FL=gb:NM_025129.1 NM_025129 fuzzy planar cell polarity protein FUZ 80199 NM_001171937 /// NM_025129 /// NR_033269 /// XM_006723397 /// XM_006723398 /// XM_006723399 /// XM_006723400 /// XM_006723401 /// XM_006723402 0001736 // establishment of planar polarity // inferred from sequence or structural similarity /// 0001843 // neural tube closure // inferred from mutant phenotype /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0010172 // embryonic body morphogenesis // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0021513 // spinal cord dorsal/ventral patterning // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0035058 // nonmotile primary cilium assembly // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045724 // positive regulation of cilium assembly // inferred from mutant phenotype /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090301 // negative regulation of neural crest formation // inferred from sequence or structural similarity /// 2000314 // negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221188_s_at NM_014430 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014430.1 /DEF=Homo sapiens cell death-inducing DFFA-like effector b (CIDEB), mRNA. /FEA=mRNA /GEN=CIDEB /PROD=cell death-inducing DFFA-like effector b /DB_XREF=gi:7656978 /UG=Hs.288835 cell death-inducing DFFA-like effector b /FL=gb:AF190901.1 gb:NM_014430.1 NM_014430 cell death-inducing DFFA-like effector b CIDEB 27141 NM_014430 /// XM_005267540 0006915 // apoptotic process // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // not recorded /// 0097194 // execution phase of apoptosis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005811 // lipid particle // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // inferred from electronic annotation /// 0004974 // leukotriene receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221189_s_at NM_025150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025150.1 /DEF=Homo sapiens hypothetical protein FLJ12528 (FLJ12528), mRNA. /FEA=mRNA /GEN=FLJ12528 /PROD=hypothetical protein FLJ12528 /DB_XREF=gi:13376742 /UG=Hs.288974 hypothetical protein FLJ12528 /FL=gb:NM_025150.1 NM_025150 microRNA 6878 /// threonyl-tRNA synthetase 2, mitochondrial (putative) MIR6878 /// TARS2 80222 /// 102465529 NM_001271895 /// NM_001271896 /// NM_025150 /// NR_073513 /// NR_073514 /// NR_106938 /// XM_006711555 /// XM_006711556 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006435 // threonyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0070159 // mitochondrial threonyl-tRNA aminoacylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004829 // threonine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation 221190_s_at NM_013326 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013326.1 /DEF=Homo sapiens colon cancer-associated protein Mic1 (MIC1), mRNA. /FEA=mRNA /GEN=MIC1 /PROD=colon cancer-associated protein Mic1 /DB_XREF=gi:7019454 /UG=Hs.289080 colon cancer-associated protein Mic1 /FL=gb:AF143536.1 gb:NM_013326.1 NM_013326 chromosome 18 open reading frame 8 C18orf8 29919 NM_001276342 /// NM_013326 /// NR_075075 /// NR_075076 /// XM_006722445 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221191_at NM_018991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018991.1 /DEF=Homo sapiens DKFZp434A0131 protein (DKFZP434A0131), mRNA. /FEA=mRNA /GEN=DKFZP434A0131 /PROD=DKFZp434A0131 protein /DB_XREF=gi:11128020 /UG=Hs.289115 DKFZp434A0131 protein /FL=gb:NM_018991.1 NM_018991 stromal antigen 3-like 3 STAG3L3 442578 NM_001013739 /// NR_040582 0005634 // nucleus // inferred from electronic annotation 221192_x_at NM_024311 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024311.1 /DEF=Homo sapiens hypothetical protein ET (ET), mRNA. /FEA=mRNA /GEN=ET /PROD=hypothetical protein ET /DB_XREF=gi:13236548 /UG=Hs.296924 hypothetical protein ET /FL=gb:BC002753.1 gb:NM_024311.1 NM_024311 major facilitator superfamily domain containing 11 MFSD11 79157 NM_001242532 /// NM_001242533 /// NM_001242534 /// NM_001242535 /// NM_001242536 /// NM_001242537 /// NM_024311 /// XM_005257661 /// XM_005257662 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221193_s_at NM_017665 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017665.1 /DEF=Homo sapiens hypothetical protein FLJ20094 (FLJ20094), mRNA. /FEA=mRNA /GEN=FLJ20094 /PROD=hypothetical protein FLJ20094 /DB_XREF=gi:8923105 /UG=Hs.29700 hypothetical protein FLJ20094 /FL=gb:NM_017665.1 NM_017665 zinc finger, CCHC domain containing 10 ZCCHC10 54819 NM_017665 /// XM_005272024 /// XM_005272025 /// XM_005272026 /// XM_005272027 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221194_s_at NM_016125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016125.1 /DEF=Homo sapiens PTD016 protein (LOC51136), mRNA. /FEA=mRNA /GEN=LOC51136 /PROD=PTD016 protein /DB_XREF=gi:7705842 /UG=Hs.30154 PTD016 protein /FL=gb:AF100745.1 gb:NM_016125.1 NM_016125 ring finger protein, transmembrane 1 /// TBC1D3P1-DHX40P1 readthrough transcribed pseudogene RNFT1 /// TBC1D3P1-DHX40P1 51136 /// 653645 NM_016125 /// NR_002924 /// XR_424860 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221195_at NM_016125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016125.1 /DEF=Homo sapiens PTD016 protein (LOC51136), mRNA. /FEA=mRNA /GEN=LOC51136 /PROD=PTD016 protein /DB_XREF=gi:7705842 /UG=Hs.30154 PTD016 protein /FL=gb:AF100745.1 gb:NM_016125.1 NM_016125 ring finger protein, transmembrane 1 RNFT1 51136 NM_016125 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221196_x_at NM_024332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024332.1 /DEF=Homo sapiens c6.1A (C6.1A), mRNA. /FEA=mRNA /GEN=C6.1A /PROD=c6.1A /DB_XREF=gi:13236582 /UG=Hs.301927 c6.1A /FL=gb:BC002999.1 gb:NM_024332.1 NM_024332 BRCA1/BRCA2-containing complex, subunit 3 BRCC3 79184 NM_001018055 /// NM_001242640 /// NM_024332 /// XM_005274749 /// XM_005274750 /// XM_005274751 /// XM_006724846 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from direct assay /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070537 // histone H2A K63-linked deubiquitination // inferred from direct assay /// 0070537 // histone H2A K63-linked deubiquitination // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000152 // nuclear ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221197_s_at NM_020985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020985.1 /DEF=Homo sapiens choline acetyltransferase (CHAT), transcript variant N1, mRNA. /FEA=mRNA /GEN=CHAT /PROD=choline acetyltransferase isoform 1 /DB_XREF=gi:11038627 /UG=Hs.302002 choline acetyltransferase /FL=gb:NM_020985.1 NM_020985 choline O-acetyltransferase CHAT 1103 NM_001142929 /// NM_001142933 /// NM_001142934 /// NM_020549 /// NM_020984 /// NM_020985 /// NM_020986 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007529 // establishment of synaptic specificity at neuromuscular junction // inferred from electronic annotation /// 0007622 // rhythmic behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from electronic annotation /// 0043179 // rhythmic excitation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004102 // choline O-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 221198_at NM_021920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021920.2 /DEF=Homo sapiens secretin (SCT), mRNA. /FEA=mRNA /GEN=SCT /PROD=secretin preproprotein /DB_XREF=gi:12545379 /UG=Hs.302005 secretin /FL=gb:NM_021920.2 NM_021920 secretin SCT 6343 NM_021920 /// XM_006718272 0008542 // visual learning // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0030157 // pancreatic juice secretion // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement 0005179 // hormone activity // non-traceable author statement 221199_at NM_022139 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022139.1 /DEF=Homo sapiens GDNF family receptor alpha 4 (GFRA4), mRNA. /FEA=mRNA /GEN=GFRA4 /PROD=GDNF family receptor alpha 4 /DB_XREF=gi:11545874 /UG=Hs.302025 GDNF family receptor alpha 4 /FL=gb:AF253318.1 gb:NM_022139.1 NM_022139 GDNF family receptor alpha 4 GFRA4 64096 NM_022139 /// NM_145762 /// NM_145763 /// XM_005260793 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0035860 // glial cell-derived neurotrophic factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0016167 // glial cell-derived neurotrophic factor receptor activity // inferred from electronic annotation 221200_at NM_022155 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022155.1 /DEF=Homo sapiens PP3227 protein (PP3227), mRNA. /FEA=mRNA /GEN=PP3227 /PROD=PP3227 protein /DB_XREF=gi:11545901 /UG=Hs.302027 PP3227 protein /FL=gb:NM_022155.1 NM_022155 endogenous retrovirus group K3, member 2 ERVK3-2 100862697 221201_s_at NM_003445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003445.1 /DEF=Homo sapiens zinc finger protein 155 (pHZ-96) (ZNF155), mRNA. /FEA=mRNA /GEN=ZNF155 /PROD=zinc finger protein 155 (pHZ-96) /DB_XREF=gi:7706778 /UG=Hs.31324 zinc finger protein 155 (pHZ-96) /FL=gb:NM_003445.1 NM_003445 zinc finger protein 155 ZNF155 7711 NM_001260486 /// NM_001260487 /// NM_001260488 /// NM_003445 /// NM_198089 /// XM_005259215 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221202_at NM_018523 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018523.1 /DEF=Homo sapiens hypothetical protein PRO2325 (PRO2325), mRNA. /FEA=mRNA /GEN=PRO2325 /PROD=hypothetical protein PRO2325 /DB_XREF=gi:8924154 /UG=Hs.31535 hypothetical protein PRO2325 /FL=gb:AF119876.1 gb:NM_018523.1 NM_018523 221203_s_at NM_018023 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018023.2 /DEF=Homo sapiens hypothetical protein FLJ10201 (FLJ10201), mRNA. /FEA=mRNA /GEN=FLJ10201 /PROD=hypothetical protein FLJ10201 /DB_XREF=gi:13492976 /UG=Hs.318127 hypothetical protein FLJ10201 /FL=gb:NM_018023.2 NM_018023 YEATS domain containing 2 YEATS2 55689 NM_018023 /// XM_005247597 /// XM_005247598 /// XM_006713688 /// XR_427369 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from physical interaction 221204_s_at NM_018058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018058.1 /DEF=Homo sapiens hypothetical protein FLJ10320 (FLJ10320), mRNA. /FEA=mRNA /GEN=FLJ10320 /PROD=hypothetical protein FLJ10320 /DB_XREF=gi:8922351 /UG=Hs.326444 chondrocyte expressed protein 68 kDa CEP-68 /FL=gb:NM_018058.1 NM_018058 cartilage acidic protein 1 CRTAC1 55118 NM_001206528 /// NM_018058 /// XM_005269938 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 221205_at NM_018041 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018041.1 /DEF=Homo sapiens hypothetical protein FLJ10254 (FLJ10254), mRNA. /FEA=mRNA /GEN=FLJ10254 /PROD=hypothetical protein FLJ10254 /DB_XREF=gi:8922314 /UG=Hs.326551 hypothetical protein FLJ10254 /FL=gb:NM_018041.1 NM_018041 221206_at NM_024521 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024521.1 /DEF=Homo sapiens hypothetical protein FLJ21459 (FLJ21459), mRNA. /FEA=mRNA /GEN=FLJ21459 /PROD=hypothetical protein FLJ21459 /DB_XREF=gi:13375661 /UG=Hs.3769 hypothetical protein FLJ21459 /FL=gb:NM_024521.1 NM_024521 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) /// PMS2 C-terminal like pseudogene PMS2 /// PMS2CL 5395 /// 441194 NM_000535 /// NR_002217 /// NR_003085 /// XM_006715742 /// XM_006715743 /// XM_006715744 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0032389 // MutLalpha complex // not recorded 0003677 // DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032138 // single base insertion or deletion binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay 221207_s_at NM_015678 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015678.1 /DEF=Homo sapiens neurobeachin (NBEA), mRNA. /FEA=mRNA /GEN=NBEA /PROD=neurobeachin /DB_XREF=gi:7657362 /UG=Hs.3821 neurobeachin /FL=gb:NM_015678.1 NM_015678 neurobeachin NBEA 26960 NM_001204197 /// NM_015678 /// XM_005266346 /// XM_005266347 /// XM_005266348 /// XM_005266350 /// XM_005266351 /// XM_005266352 /// XM_006719803 /// XM_006719804 /// XM_006719805 /// XM_006719806 0008104 // protein localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 221208_s_at NM_024631 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024631.1 /DEF=Homo sapiens hypothetical protein FLJ23342 (FLJ23342), mRNA. /FEA=mRNA /GEN=FLJ23342 /PROD=hypothetical protein FLJ23342 /DB_XREF=gi:13375859 /UG=Hs.38592 hypothetical protein FLJ23342 /FL=gb:NM_024631.1 NM_024631 Myb/SANT-like DNA-binding domain containing 2 MSANTD2 79684 NM_024631 /// XM_005271673 /// XM_005271674 /// XM_005271675 /// XM_005271676 /// XM_006718905 /// XM_006718906 /// XM_006718907 /// XM_006718908 221209_s_at NM_020157 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020157.1 /DEF=Homo sapiens otoraplin (OTOR), mRNA. /FEA=mRNA /GEN=OTOR /PROD=otoraplin /DB_XREF=gi:9910469 /UG=Hs.41119 otoraplin /FL=gb:AF233261.1 gb:NM_020157.1 NM_020157 otoraplin OTOR 56914 NM_020157 /// XM_005260762 0001502 // cartilage condensation // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221210_s_at NM_030769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030769.1 /DEF=Homo sapiens hypothetical protein similar to swine acylneuraminate lyase (C1ORF13), mRNA. /FEA=mRNA /GEN=C1ORF13 /PROD=hypothetical protein similar to swineacylneuraminate lyase /DB_XREF=gi:13540532 /FL=gb:NM_030769.1 NM_030769 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) NPL 80896 NM_001200050 /// NM_001200051 /// NM_001200052 /// NM_001200056 /// NM_030769 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008747 // N-acetylneuraminate lyase activity // inferred from sequence or structural similarity /// 0016829 // lyase activity // inferred from electronic annotation 221211_s_at NM_020152 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020152.1 /DEF=Homo sapiens c21orf7 form A-D (C21orf7), mRNA. /FEA=mRNA /GEN=C21orf7 /PROD=c21orf7 form A-D /DB_XREF=gi:9910145 /UG=Hs.41267 c21orf7 form A-D /FL=gb:AF269161.1 gb:NM_020152.1 NM_020152 MAP3K7 C-terminal like MAP3K7CL 56911 NM_001286617 /// NM_001286618 /// NM_001286619 /// NM_001286620 /// NM_001286622 /// NM_001286623 /// NM_001286624 /// NM_001286634 /// NM_020152 /// XM_006724033 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221212_x_at NM_018313 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018313.1 /DEF=Homo sapiens hypothetical protein FLJ11064 (FLJ11064), mRNA. /FEA=mRNA /GEN=FLJ11064 /PROD=hypothetical protein FLJ11064 /DB_XREF=gi:8922847 /UG=Hs.44143 polybromo 1 /FL=gb:NM_018313.1 NM_018313 polybromo 1 PBRM1 55193 NM_018165 /// NM_018313 /// NM_181041 /// NM_181042 /// XM_005265275 /// XM_005265279 /// XM_005265280 /// XM_005265282 /// XM_005265283 /// XM_005265288 /// XM_006713220 /// XM_006713221 /// XM_006713222 /// XM_006713223 /// XM_006713224 /// XM_006713225 /// XM_006713226 /// XM_006713227 /// XM_006713228 /// XM_006713229 /// XM_006713230 /// XM_006713231 /// XM_006713232 /// XM_006713233 /// XM_006713234 0001890 // placenta development // inferred from electronic annotation /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221213_s_at NM_017661 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017661.1 /DEF=Homo sapiens hypothetical protein FLJ20086 (FLJ20086), mRNA. /FEA=mRNA /GEN=FLJ20086 /PROD=hypothetical protein FLJ20086 /DB_XREF=gi:8923096 /UG=Hs.46821 hypothetical protein FLJ20086 /FL=gb:NM_017661.1 NM_017661 uncharacterized LOC145783 /// zinc finger protein 280D LOC145783 /// ZNF280D 54816 /// 145783 NM_001002843 /// NM_001002844 /// NM_001288588 /// NM_001288589 /// NM_017661 /// NR_015419 /// XM_005254481 /// XM_005254483 /// XM_005254484 /// XM_005254485 /// XM_006720581 /// XR_243105 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221214_s_at NM_015537 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015537.1 /DEF=Homo sapiens DKFZP586J1624 protein (DKFZP586J1624), mRNA. /FEA=mRNA /GEN=DKFZP586J1624 /PROD=DKFZP586J1624 protein /DB_XREF=gi:7661679 /UG=Hs.4964 DKFZP586J1624 protein /FL=gb:NM_015537.1 NM_015537 microRNA 7114 /// NMDA receptor synaptonuclear signaling and neuronal migration factor MIR7114 /// NSMF 26012 /// 102466223 NM_001130969 /// NM_001130970 /// NM_001130971 /// NM_001178064 /// NM_015537 /// NR_106964 /// XM_005266061 /// XM_005266062 0035307 // positive regulation of protein dephosphorylation // inferred from sequence or structural similarity /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0048168 // regulation of neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048814 // regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity /// 0071257 // cellular response to electrical stimulus // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005719 // nuclear euchromatin // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0097440 // apical dendrite // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from sequence or structural similarity 221215_s_at NM_020639 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020639.1 /DEF=Homo sapiens ankyrin repeat domain 3 (ANKRD3), mRNA. /FEA=mRNA /GEN=ANKRD3 /PROD=ankyrin repeat domain 3 /DB_XREF=gi:10190675 /UG=Hs.55565 ankyrin repeat domain 3 /FL=gb:NM_020639.1 NM_020639 receptor-interacting serine-threonine kinase 4 RIPK4 54101 NM_020639 0002009 // morphogenesis of an epithelium // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221216_s_at NM_012236 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012236.1 /DEF=Homo sapiens sex comb on midleg homolog 1 (SCMH1), mRNA. /FEA=mRNA /GEN=SCMH1 /PROD=sex comb on midleg homolog 1 /DB_XREF=gi:6912641 /UG=Hs.57475 sex comb on midleg homolog 1 /FL=gb:AF149045.1 gb:NM_012236.1 NM_012236 sex comb on midleg homolog 1 (Drosophila) SCMH1 22955 NM_001031694 /// NM_001172218 /// NM_001172219 /// NM_001172220 /// NM_001172221 /// NM_001172222 /// NM_012236 /// XM_005270639 /// XM_006710462 /// XM_006710463 /// XM_006710464 /// XM_006710465 /// XM_006710466 /// XM_006710467 /// XM_006710468 /// XM_006710469 /// XM_006710470 /// XR_426594 /// XR_426595 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016458 // gene silencing // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // traceable author statement /// 0010369 // chromocenter // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221217_s_at NM_018723 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018723.1 /DEF=Homo sapiens ataxin 2-binding protein 1 (A2BP1), mRNA. /FEA=mRNA /GEN=A2BP1 /PROD=ataxin 2-binding protein 1 /DB_XREF=gi:8922072 /UG=Hs.57937 ataxin 2-binding protein 1 /FL=gb:AF107203.1 gb:NM_018723.1 NM_018723 RNA binding protein, fox-1 homolog (C. elegans) 1 RBFOX1 54715 NM_001142333 /// NM_001142334 /// NM_018723 /// NM_145891 /// NM_145892 /// NM_145893 /// XM_005255379 /// XM_005255380 /// XM_005255381 /// XM_005255382 /// XM_005255383 /// XM_005255384 /// XM_005255385 /// XM_005255386 /// XM_005255387 /// XM_005255388 /// XM_005255389 /// XM_005255390 /// XM_005255391 /// XM_005255393 /// XM_005255394 /// XM_006720896 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from electronic annotation /// 0050658 // RNA transport // non-traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 221218_s_at NM_022445 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022445.1 /DEF=Homo sapiens mouse thiamin pyrophosphokinase homolog (TPK1), mRNA. /FEA=mRNA /GEN=TPK1 /PROD=mouse thiamin pyrophosphokinase homolog /DB_XREF=gi:11990617 /UG=Hs.58715 thiamine pyrophosphokinase /FL=gb:NM_022445.1 NM_022445 thiamin pyrophosphokinase 1 TPK1 27010 NM_001042482 /// NM_022445 /// XM_005249970 /// XM_005249971 /// XM_005249972 /// XM_005249974 /// XM_006715924 /// XM_006715925 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006772 // thiamine metabolic process // inferred from electronic annotation /// 0009229 // thiamine diphosphate biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042723 // thiamine-containing compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004788 // thiamine diphosphokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221219_s_at NM_017566 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017566.1 /DEF=Homo sapiens hypothetical protein DKFZp434G0522 (DKFZp434G0522), mRNA. /FEA=mRNA /GEN=DKFZp434G0522 /PROD=hypothetical protein DKFZp434G0522 /DB_XREF=gi:8922135 /UG=Hs.67991 hypothetical protein DKFZp434G0522 /FL=gb:NM_017566.1 NM_017566 kelch domain containing 4 KLHDC4 54758 NM_001184854 /// NM_001184856 /// NM_017566 /// XM_005255994 /// XM_005255998 /// XM_005255999 /// XM_005256001 /// XM_006721201 /// XM_006721202 /// XM_006721203 /// XM_006721204 /// XM_006721205 /// XR_429719 /// XR_429720 0005515 // protein binding // inferred from physical interaction 221220_s_at NM_017988 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017988.1 /DEF=Homo sapiens hypothetical protein FLJ10074 (FLJ10074), mRNA. /FEA=mRNA /GEN=FLJ10074 /PROD=hypothetical protein FLJ10074 /DB_XREF=gi:8922217 /UG=Hs.71573 hypothetical protein FLJ10074 /FL=gb:NM_017988.1 NM_017988 SCY1-like 2 (S. cerevisiae) SCYL2 55681 NM_017988 /// XM_005269018 /// XM_006719497 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from direct assay /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221221_s_at NM_017415 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017415.1 /DEF=Homo sapiens kelch (Drosophila)-like 3 (KLHL3), mRNA. /FEA=mRNA /GEN=KLHL3 /PROD=kelch (Drosophila)-like 3 /DB_XREF=gi:8393671 /UG=Hs.7388 kelch (Drosophila)-like 3 /FL=gb:AF208068.1 gb:NM_017415.1 NM_017415 kelch-like family member 3 KLHL3 26249 NM_001257194 /// NM_001257195 /// NM_017415 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0050801 // ion homeostasis // inferred from mutant phenotype /// 0070294 // renal sodium ion absorption // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0072156 // distal tubule morphogenesis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221222_s_at NM_017860 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017860.1 /DEF=Homo sapiens hypothetical protein FLJ20519 (FLJ20519), mRNA. /FEA=mRNA /GEN=FLJ20519 /PROD=hypothetical protein FLJ20519 /DB_XREF=gi:8923488 /UG=Hs.79457 hypothetical protein FLJ20519 /FL=gb:NM_017860.1 NM_017860 chromosome 1 open reading frame 56 C1orf56 54964 NM_017860 /// XM_006711401 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 221223_x_at NM_013324 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013324.2 /DEF=Homo sapiens cytokine inducible SH2-containing protein (CISH), mRNA. /FEA=mRNA /GEN=CISH /PROD=cytokine-inducible SH2-containing protein /DB_XREF=gi:7242149 /UG=Hs.8257 cytokine inducible SH2-containing protein /FL=gb:AF132297.2 gb:NM_013324.2 NM_013324 cytokine inducible SH2-containing protein CISH 1154 NM_013324 /// NM_145071 /// XM_005264846 0001558 // regulation of cell growth // non-traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221224_s_at NM_024819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024819.1 /DEF=Homo sapiens hypothetical protein FLJ22955 (FLJ22955), mRNA. /FEA=mRNA /GEN=FLJ22955 /PROD=hypothetical protein FLJ22955 /DB_XREF=gi:13376213 /UG=Hs.83097 hypothetical protein FLJ22955 /FL=gb:NM_024819.1 NM_024819 dephospho-CoA kinase domain containing DCAKD 79877 NM_001128631 /// NM_001288654 /// NM_001288655 /// NM_024819 /// XM_005257688 /// XM_006722091 /// XM_006722092 /// XM_006722093 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004140 // dephospho-CoA kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 221225_at NM_024819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024819.1 /DEF=Homo sapiens hypothetical protein FLJ22955 (FLJ22955), mRNA. /FEA=mRNA /GEN=FLJ22955 /PROD=hypothetical protein FLJ22955 /DB_XREF=gi:13376213 /UG=Hs.83097 hypothetical protein FLJ22955 /FL=gb:NM_024819.1 NM_024819 dephospho-CoA kinase domain containing DCAKD 79877 NM_001128631 /// NM_001288654 /// NM_001288655 /// NM_024819 /// XM_005257688 /// XM_006722091 /// XM_006722092 /// XM_006722093 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004140 // dephospho-CoA kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 221226_s_at NM_018674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018674.1 /DEF=Homo sapiens putative acid-sensing ion channel (ASIC4), mRNA. /FEA=mRNA /GEN=ASIC4 /PROD=putative acid-sensing ion channel /DB_XREF=gi:8922082 /UG=Hs.87469 putative acid-sensing ion channel /FL=gb:NM_018674.1 NM_018674 acid-sensing (proton-gated) ion channel family member 4 ASIC4 55515 NM_018674 /// NM_182847 /// XM_005246671 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // traceable author statement /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0015081 // sodium ion transmembrane transporter activity // traceable author statement 221227_x_at NM_017421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017421.1 /DEF=Homo sapiens methyltransferase COQ3 (COQ3), mRNA. /FEA=mRNA /GEN=COQ3 /PROD=methyltransferase COQ3 /DB_XREF=gi:8393176 /FL=gb:NM_017421.1 NM_017421 coenzyme Q3 methyltransferase COQ3 51805 NM_017421 /// XM_005267018 /// XM_006715500 /// XM_006715501 0006071 // glycerol metabolic process // inferred from genetic interaction /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from genetic interaction /// 0006744 // ubiquinone biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from reviewed computational analysis /// 0005759 // mitochondrial matrix // traceable author statement 0004395 // hexaprenyldihydroxybenzoate methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008425 // 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity // inferred from electronic annotation /// 0008689 // 3-demethylubiquinone-9 3-O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221228_s_at NM_016528 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016528.1 /DEF=Homo sapiens hydroxyacid oxidase 3 (medium-chain) (HAO3), mRNA. /FEA=mRNA /GEN=HAO3 /PROD=hydroxyacid oxidase 3 /DB_XREF=gi:7706074 /FL=gb:NM_016528.1 NM_016528 0018924 // mandelate metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003973 // (S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0052852 // very-long-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation /// 0052853 // long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity // inferred from electronic annotation /// 0052854 // medium-chain-(S)-2-hydroxy-acid oxidase activity // inferred from electronic annotation 221229_s_at NM_017910 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017910.2 /DEF=Homo sapiens hypothetical protein FLJ20628 (FLJ20628), mRNA. /FEA=mRNA /GEN=FLJ20628 /PROD=hypothetical protein FLJ20628 /DB_XREF=gi:13435382 /FL=gb:NM_017910.2 NM_017910 tRNA methyltransferase 61 homolog B (S. cerevisiae) TRMT61B 55006 NM_017910 /// XM_005264393 /// XM_005264394 /// XM_006712037 /// XR_244945 0006464 // cellular protein modification process // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0070901 // mitochondrial tRNA methylation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0031515 // tRNA (m1A) methyltransferase complex // inferred from electronic annotation 0004719 // protein-L-isoaspartate (D-aspartate) O-methyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016429 // tRNA (adenine-N1-)-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 221230_s_at NM_016374 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016374.2 /DEF=Homo sapiens RBP1-like protein (BCAA), mRNA. /FEA=mRNA /GEN=BCAA /PROD=RBP1-like protein /DB_XREF=gi:13518237 /FL=gb:NM_016374.2 NM_016374 AT rich interactive domain 4B (RBP1-like) ARID4B 51742 NM_001206794 /// NM_016374 /// NM_031371 /// XM_005273160 /// XM_006711781 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034773 // histone H4-K20 trimethylation // inferred from electronic annotation /// 0036124 // histone H3-K9 trimethylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221231_s_at NM_017970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017970.1 /DEF=Homo sapiens hypothetical protein FLJ10008 (FLJ10008), mRNA. /FEA=mRNA /GEN=FLJ10008 /PROD=hypothetical protein FLJ10008 /DB_XREF=gi:13540481 /FL=gb:NM_017970.1 NM_017970 NRDE-2, necessary for RNA interference, domain containing NRDE2 55051 NM_017970 /// NM_199043 /// XM_006720186 221232_s_at NM_020349 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020349.1 /DEF=Homo sapiens ankyrin repeat domain 2 (stretch responsive muscle) (ANKRD2), mRNA. /FEA=mRNA /GEN=ANKRD2 /PROD=ankyrin repeat domain 2 (stretch responsivemuscle) /DB_XREF=gi:13540483 /FL=gb:NM_020349.1 NM_020349 ankyrin repeat domain 2 (stretch responsive muscle) ANKRD2 26287 NM_001129981 /// NM_001291218 /// NM_001291219 /// NM_020349 0006936 // muscle contraction // non-traceable author statement /// 0007517 // muscle organ development // non-traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from mutant phenotype 0000791 // euchromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0031674 // I band // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031432 // titin binding // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction 221233_s_at NM_020819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020819.1 /DEF=Homo sapiens KIAA1411 protein (KIAA1411), mRNA. /FEA=mRNA /GEN=KIAA1411 /PROD=KIAA1411 protein /DB_XREF=gi:13540485 /FL=gb:NM_020819.1 NM_020819 family with sequence similarity 135, member A FAM135A 57579 NM_001105531 /// NM_001162529 /// NM_020819 /// XM_005248743 /// XM_005248744 /// XM_005248745 /// XM_005248746 /// XM_005248747 /// XM_005248748 /// XM_005248749 /// XM_005248750 /// XM_005248751 221234_s_at NM_021813 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021813.1 /DEF=Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 2 (BACH2), mRNA. /FEA=mRNA /GEN=BACH2 /PROD=BTB and CNC homology 1, basic leucine zippertranscription factor 2 /DB_XREF=gi:13540489 /FL=gb:NM_021813.1 NM_021813 BTB and CNC homology 1, basic leucine zipper transcription factor 2 BACH2 60468 NM_001170794 /// NM_021813 /// XM_005248758 /// XM_005248759 /// XM_006715545 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221235_s_at NM_030825 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030825.1 /DEF=Homo sapiens hypothetical protein FLJ22294 (FLJ22294), mRNA. /FEA=mRNA /GEN=FLJ22294 /PROD=hypothetical protein FLJ22294 /DB_XREF=gi:13540497 /FL=gb:NM_030825.1 NM_030825 transforming growth factor, beta receptor associated protein 1 TGFBRAP1 9392 NM_001142621 /// NM_004257 /// XM_006712860 /// XM_006712861 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005160 // transforming growth factor beta receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay 221236_s_at NM_030795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030795.1 /DEF=Homo sapiens stathmin-like-protein RB3 (RB3), mRNA. /FEA=mRNA /GEN=RB3 /PROD=stathmin-like-protein RB3 /DB_XREF=gi:13540510 /FL=gb:NM_030795.1 NM_030795 stathmin-like 4 STMN4 81551 NM_001283053 /// NM_001283054 /// NM_001283055 /// NM_030795 /// XM_005273652 /// XM_005273655 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 221237_s_at NM_030758 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030758.1 /DEF=Homo sapiens oxysterol binding protein-like 1 (OSBPL1), mRNA. /FEA=mRNA /GEN=OSBPL1 /PROD=oxysterol binding protein-like 1 /DB_XREF=gi:13540512 /FL=gb:NM_030758.1 NM_030758 oxysterol binding protein 2 OSBP2 23762 NM_001003812 /// NM_001282738 /// NM_001282739 /// NM_001282740 /// NM_001282741 /// NM_001282742 /// NM_030758 /// XM_005261465 /// XM_006724203 /// XM_006724204 /// XM_006724205 /// XM_006724206 /// XM_006724207 /// XM_006724208 /// XM_006724209 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay 221238_at NM_030763 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030763.1 /DEF=Homo sapiens nucleosomal binding protein 1 (NSBP1), mRNA. /FEA=mRNA /GEN=NSBP1 /PROD=nucleosomal binding protein 1 /DB_XREF=gi:13540522 /FL=gb:NM_030763.1 NM_030763 high mobility group nucleosome binding domain 5 HMGN5 79366 NM_030763 /// XM_006724688 /// XM_006724689 /// XM_006724690 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // non-traceable author statement /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221239_s_at NM_030764 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030764.1 /DEF=Homo sapiens SH2 domain-containing phosphatase anchor protein 1 (SPAP1), mRNA. /FEA=mRNA /GEN=SPAP1 /PROD=SH2 domain-containing phosphatase anchor protein1 /DB_XREF=gi:13540524 /FL=gb:NM_030764.1 NM_030764 Fc receptor-like 2 FCRL2 79368 NM_030764 /// NM_138738 /// XM_005245486 /// XM_006711531 /// XM_006711532 /// XM_006711533 /// XM_006711534 /// XM_006711535 /// XM_006711536 0007267 // cell-cell signaling // non-traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from physical interaction 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 221240_s_at NM_030765 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030765.1 /DEF=Homo sapiens beta-1,3-N-acetylglucosaminyltransferase bGn-T4 (B3GN-T4), mRNA. /FEA=mRNA /GEN=B3GN-T4 /PROD=beta-1,3-N-acetylglucosaminyltransferase bGn-T4 /DB_XREF=gi:13540526 /FL=gb:NM_030765.1 NM_030765 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 B3GNT4 79369 NM_030765 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008378 // galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 221241_s_at NM_030766 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030766.1 /DEF=Homo sapiens apoptosis regulator BCL-G (BCLG), mRNA. /FEA=mRNA /GEN=BCLG /PROD=apoptosis regulator BCL-G /DB_XREF=gi:13540528 /FL=gb:NM_030766.1 NM_030766 BCL2-like 14 (apoptosis facilitator) BCL2L14 79370 NM_030766 /// NM_138722 /// NM_138723 /// NM_138724 /// XM_006719151 0006915 // apoptotic process // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 221242_at NM_025051 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025051.1 /DEF=Homo sapiens hypothetical protein FLJ23022 (FLJ23022), mRNA. /FEA=mRNA /GEN=FLJ23022 /PROD=hypothetical protein FLJ23022 /DB_XREF=gi:13376579 /UG=Hs.287717 hypothetical protein FLJ23022 /FL=gb:NM_025051.1 NM_025051 221243_s_at NM_031270 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031270.1 /DEF=Homo sapiens PRO1596 protein (PRO1596), mRNA. /FEA=mRNA /GEN=PRO1596 /PROD=PRO1596 protein /DB_XREF=gi:13775171 /FL=gb:NM_031270.1 NM_031270 uncharacterized LOC29013 PRO1596 29013 221244_s_at NM_031268 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031268.1 /DEF=Homo sapiens PRO0461 protein (PRO0461), mRNA. /FEA=mRNA /GEN=PRO0461 /PROD=PRO0461 protein /DB_XREF=gi:13775167 /FL=gb:NM_031268.1 NM_031268 3-phosphoinositide dependent protein kinase 1 PDPK1 5170 NM_001261816 /// NM_002613 /// NM_031268 /// XM_005255356 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0010594 // regulation of endothelial cell migration // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043304 // regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004676 // 3-phosphoinositide-dependent protein kinase activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from mutant phenotype /// 0016301 // kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 221245_s_at NM_030804 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030804.1 /DEF=Homo sapiens hypothetical protein DKFZp434E2135 (DKFZP434E2135), mRNA. /FEA=mRNA /GEN=DKFZP434E2135 /PROD=hypothetical protein DKFZp434E2135 /DB_XREF=gi:13540591 /FL=gb:NM_030804.1 NM_030804 frizzled class receptor 5 FZD5 7855 NM_003468 /// NM_030804 0000578 // embryonic axis specification // inferred from direct assay /// 0001525 // angiogenesis // not recorded /// 0001944 // vasculature development // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008406 // gonad development // not recorded /// 0008595 // anterior/posterior axis specification, embryo // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031076 // embryonic camera-type eye development // not recorded /// 0031077 // post-embryonic camera-type eye development // not recorded /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // not recorded /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0060061 // Spemann organizer formation // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060561 // apoptotic process involved in morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // not recorded /// 0071219 // cellular response to molecule of bacterial origin // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0042995 // cell projection // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0042813 // Wnt-activated receptor activity // inferred by curator 221246_x_at NM_018274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018274.2 /DEF=Homo sapiens tensin (TNS), mRNA. /FEA=mRNA /GEN=TNS /PROD=7145 /DB_XREF=gi:13775159 /FL=gb:NM_018274.2 NM_018274 tensin 1 TNS1 7145 NM_022648 /// XM_005246825 /// XM_005246826 /// XM_006712721 /// XM_006712722 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221247_s_at NM_030798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030798.1 /DEF=Homo sapiens hypothetical protein DKFZp434D0421 (DKFZP434D0421), mRNA. /FEA=mRNA /GEN=DKFZP434D0421 /PROD=hypothetical protein DKFZp434D0421 /DB_XREF=gi:13540581 /FL=gb:NM_030798.1 NM_030798 Williams-Beuren syndrome chromosome region 16 WBSCR16 81554 NM_001281441 /// NM_030798 /// NM_148842 0005739 // mitochondrion // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 221248_s_at NM_023034 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023034.1 /DEF=Homo sapiens Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant long, mRNA. /FEA=mRNA /GEN=WHSC1L1 /PROD=WHSC1L1 protein isoform long /DB_XREF=gi:13699810 /FL=gb:NM_023034.1 NM_023034 Wolf-Hirschhorn syndrome candidate 1-like 1 WHSC1L1 54904 NM_017778 /// NM_023034 /// XM_005273547 /// XM_005273548 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from direct assay /// 0030154 // cell differentiation // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0034968 // histone lysine methylation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221249_s_at NM_030802 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030802.1 /DEF=Homo sapiens CEBP-induced protein (LOC81558), mRNA. /FEA=mRNA /GEN=LOC81558 /PROD=CEBP-induced protein /DB_XREF=gi:13540589 /FL=gb:NM_030802.1 NM_030802 family with sequence similarity 117, member A FAM117A 81558 NM_030802 221250_s_at NM_031300 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031300.1 /DEF=Homo sapiens hypothetical protein MGC2383 (MGC2383), mRNA. /FEA=mRNA /GEN=MGC2383 /PROD=hypothetical protein MGC2383 /DB_XREF=gi:13775221 /FL=gb:NM_031300.1 NM_031300 MAX dimerization protein 3 MXD3 83463 NM_001142935 /// NM_031300 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 221251_x_at NM_031288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031288.1 /DEF=Homo sapiens PAP-1 binding protein (PAPA-1), mRNA. /FEA=mRNA /GEN=PAPA-1 /PROD=PAP-1 binding protein /DB_XREF=gi:13775201 /FL=gb:NM_031288.1 NM_031288 INO80 complex subunit B /// INO80B-WBP1 readthrough (NMD candidate) INO80B /// INO80B-WBP1 83444 /// 100532735 NM_031288 /// NR_037849 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221252_s_at NM_031289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031289.1 /DEF=Homo sapiens hypothetical protein MGC3146 (MGC3146), mRNA. /FEA=mRNA /GEN=MGC3146 /PROD=hypothetical protein MGC3146 /DB_XREF=gi:13775203 /FL=gb:NM_031289.1 NM_031289 germ cell associated 1 GSG1 83445 NM_001080554 /// NM_001080555 /// NM_001206842 /// NM_001206843 /// NM_001206845 /// NM_031289 /// NM_153823 /// XM_005253493 /// XM_005253495 /// XM_005253497 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0070063 // RNA polymerase binding // inferred from electronic annotation 221253_s_at NM_030810 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030810.1 /DEF=Homo sapiens hypothetical protein MGC3178 (MGC3178), mRNA. /FEA=mRNA /GEN=MGC3178 /PROD=hypothetical protein MGC3178 /DB_XREF=gi:13540603 /FL=gb:NM_030810.1 NM_030810 BLOC1S5-TXNDC5 readthrough (NMD candidate) /// thioredoxin domain containing 5 (endoplasmic reticulum) BLOC1S5-TXNDC5 /// TXNDC5 81567 /// 100526836 NM_001145549 /// NM_022085 /// NM_030810 /// NR_037616 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043277 // apoptotic cell clearance // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005783 // endoplasmic reticulum // not recorded /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031083 // BLOC-1 complex // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 221254_s_at NM_031220 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031220.1 /DEF=Homo sapiens PYK2 N-terminal domain-interacting receptor 1 (NIR1), mRNA. /FEA=mRNA /GEN=NIR1 /PROD=PYK2 N-terminal domain-interacting receptor 1 /DB_XREF=gi:13654295 /FL=gb:NM_031220.1 NM_031220 PITPNM family member 3 PITPNM3 83394 NM_001165966 /// NM_031220 /// XM_006721582 0006810 // transport // inferred from electronic annotation /// 0015914 // phospholipid transport // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0030971 // receptor tyrosine kinase binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221255_s_at NM_031298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031298.1 /DEF=Homo sapiens hypothetical protein MGC2963 (MGC2963), mRNA. /FEA=mRNA /GEN=MGC2963 /PROD=hypothetical protein MGC2963 /DB_XREF=gi:13775219 /FL=gb:NM_031298.1 NM_031298 ER membrane protein complex subunit 6 EMC6 83460 NM_001014764 /// NM_031298 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 221256_s_at NM_031219 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031219.1 /DEF=Homo sapiens hypothetical protein MGC12904 (MGC12904), mRNA. /FEA=mRNA /GEN=MGC12904 /PROD=hypothetical protein MGC12904 /DB_XREF=gi:13654293 /FL=gb:NM_031219.1 NM_031219 haloacid dehalogenase-like hydrolase domain containing 3 HDHD3 81932 NM_031219 /// XM_005252251 /// XM_005252252 /// XM_006717296 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 221257_x_at NM_030793 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030793.1 /DEF=Homo sapiens hypothetical protein SP329 (SP329), mRNA. /FEA=mRNA /GEN=SP329 /PROD=hypothetical protein SP329 /DB_XREF=gi:13540573 /FL=gb:NM_030793.1 NM_030793 F-box protein 38 FBXO38 81545 NM_001271723 /// NM_030793 /// NM_205836 /// XM_005268513 /// XM_006714796 /// XM_006714797 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221258_s_at NM_031217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031217.1 /DEF=Homo sapiens hypothetical protein DKFZp434G2226 (DKFZP434G2226), mRNA. /FEA=mRNA /GEN=DKFZP434G2226 /PROD=hypothetical protein DKFZp434G2226 /DB_XREF=gi:13654289 /FL=gb:NM_031217.1 NM_031217 kinesin family member 18A KIF18A 81930 NM_031217 0000278 // mitotic cell cycle // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007019 // microtubule depolymerization // inferred from direct assay /// 0007080 // mitotic metaphase plate congression // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005828 // kinetochore microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008574 // plus-end-directed microtubule motor activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay /// 0070463 // tubulin-dependent ATPase activity // inferred from direct assay 221259_s_at NM_031276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031276.1 /DEF=Homo sapiens testis expressed sequence 11 (TEX11), mRNA. /FEA=mRNA /GEN=TEX11 /PROD=testis expressed sequence 11 /DB_XREF=gi:13775183 /FL=gb:NM_031276.1 NM_031276 testis expressed 11 TEX11 56159 NM_001003811 /// NM_031276 0000712 // resolution of meiotic recombination intermediates // inferred from electronic annotation /// 0006311 // meiotic gene conversion // inferred from sequence or structural similarity /// 0007060 // male meiosis chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from sequence or structural similarity /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0051026 // chiasma assembly // inferred from electronic annotation 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from sequence or structural similarity /// 0000801 // central element // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221260_s_at NM_030809 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030809.1 /DEF=Homo sapiens chromosome 12 open reading frame 2 (C12orf2), mRNA. /FEA=mRNA /GEN=C12orf2 /PROD=chromosome 12 open reading frame 2 /DB_XREF=gi:13540601 /FL=gb:NM_030809.1 NM_030809 cysteine-serine-rich nuclear protein 2 CSRNP2 81566 NM_030809 /// NR_045072 /// XM_006719621 /// XM_006719622 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221261_x_at NM_030801 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030801.1 /DEF=Homo sapiens MAGE1 protein (MAGE1), mRNA. /FEA=mRNA /GEN=MAGE1 /PROD=MAGE1 protein /DB_XREF=gi:13540587 /FL=gb:NM_030801.1 NM_030801 melanoma antigen family D, 4 /// melanoma antigen family D, 4B /// small nucleolar RNA, H/ACA box 11D /// small nucleolar RNA, H/ACA box 11E MAGED4 /// MAGED4B /// SNORA11D /// SNORA11E 81557 /// 728239 /// 100124541 /// 101340250 NM_001098800 /// NM_001242362 /// NM_001272061 /// NM_001272062 /// NM_001272063 /// NM_030801 /// NM_177535 /// NM_177537 /// NR_003711 /// NR_102368 /// XM_005276713 /// XM_006724607 /// XM_006724608 /// XM_006726845 221262_s_at NM_030807 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030807.1 /DEF=Homo sapiens glucose transporter protein 10 (GLUT10), mRNA. /FEA=mRNA /GEN=GLUT10 /PROD=glucose transporter protein 10 /DB_XREF=gi:13540597 /FL=gb:NM_030807.1 NM_030807 solute carrier family 2 (facilitated glucose transporter), member 11 SLC2A11 66035 NM_001024938 /// NM_001024939 /// NM_001282864 /// NM_030807 /// NR_104247 /// NR_104248 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 221263_s_at NM_031287 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031287.1 /DEF=Homo sapiens hypothetical protein MGC3133 (MGC3133), mRNA. /FEA=mRNA /GEN=MGC3133 /PROD=hypothetical protein MGC3133 /DB_XREF=gi:13775199 /FL=gb:NM_031287.1 NM_031287 splicing factor 3b, subunit 5, 10kDa SF3B5 83443 NM_031287 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005689 // U12-type spliceosomal complex // inferred from direct assay 221264_s_at NM_031214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031214.1 /DEF=Homo sapiens hypothetical protein (AF311304), mRNA. /FEA=mRNA /GEN=AF311304 /PROD=hypothetical protein /DB_XREF=gi:13654285 /FL=gb:NM_031214.1 NM_031214 TAR DNA binding protein TARDBP 23435 NM_007375 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221265_s_at NM_030800 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030800.1 /DEF=Homo sapiens hypothetical protein DKFZp564O1664 (DKFZP564O1664), mRNA. /FEA=mRNA /GEN=DKFZP564O1664 /PROD=hypothetical protein DKFZp564O1664 /DB_XREF=gi:13540585 /FL=gb:NM_030800.1 NM_030800 von Willebrand factor A domain containing 9 VWA9 81556 NM_001136043 /// NM_001207058 /// NM_001207059 /// NM_030800 /// NR_045104 /// NR_045105 /// NR_045106 /// NR_045107 /// NR_045901 /// XM_006720708 /// XM_006720709 /// XM_006720710 /// XM_006720711 0005737 // cytoplasm // inferred from direct assay 221266_s_at NM_030788 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030788.1 /DEF=Homo sapiens DC-specific transmembrane protein (LOC81501), mRNA. /FEA=mRNA /GEN=LOC81501 /PROD=DC-specific transmembrane protein /DB_XREF=gi:13540564 /FL=gb:NM_030788.1 NM_030788 dendrocyte expressed seven transmembrane protein DCSTAMP 81501 NM_001257317 /// NM_030788 /// XM_005251075 0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0034241 // positive regulation of macrophage fusion // inferred from sequence or structural similarity /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from sequence or structural similarity /// 0071353 // cellular response to interleukin-4 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072675 // osteoclast fusion // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation 221267_s_at NM_031213 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031213.1 /DEF=Homo sapiens hypothetical protein MGC:5244, (MGC:5244), mRNA. /FEA=mRNA /GEN=MGC:5244 /PROD=hypothetical protein MGC:5244, /DB_XREF=gi:13654283 /FL=gb:NM_031213.1 NM_031213 abhydrolase domain containing 17A ABHD17A 81926 NM_001130111 /// NM_031213 /// XM_006722918 0008152 // metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 221268_s_at NM_030791 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030791.1 /DEF=Homo sapiens sphingosine-1-phosphatase (LOC81537), mRNA. /FEA=mRNA /GEN=LOC81537 /PROD=sphingosine-1-phosphatase /DB_XREF=gi:13540568 /FL=gb:NM_030791.1 NM_030791 sphingosine-1-phosphate phosphatase 1 SGPP1 81537 NM_030791 /// XM_006720264 0006665 // sphingolipid metabolic process // traceable author statement /// 0006668 // sphinganine-1-phosphate metabolic process // inferred from electronic annotation /// 0006670 // sphingosine metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042392 // sphingosine-1-phosphate phosphatase activity // inferred from electronic annotation 221269_s_at NM_031286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031286.1 /DEF=Homo sapiens SH3BGRL3-like protein (SH3BGRL3), mRNA. /FEA=mRNA /GEN=SH3BGRL3 /PROD=SH3BGRL3-like protein /DB_XREF=gi:13775197 /FL=gb:NM_031286.1 NM_031286 SH3 domain binding glutamate-rich protein like 3 SH3BGRL3 83442 NM_031286 0030834 // regulation of actin filament depolymerization // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005100 // Rho GTPase activator activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from physical interaction 221270_s_at NM_031209 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031209.1 /DEF=Homo sapiens tRNA-guanine transglycosylase (TGT), mRNA. /FEA=mRNA /GEN=TGT /PROD=tRNA-guanine transglycosylase /DB_XREF=gi:13654275 /FL=gb:NM_031209.1 NM_031209 queuine tRNA-ribosyltransferase 1 QTRT1 81890 NM_031209 0006400 // tRNA modification // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008616 // queuosine biosynthetic process // inferred from electronic annotation /// 0008616 // queuosine biosynthetic process // inferred from sequence or structural similarity /// 0008616 // queuosine biosynthetic process // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0008479 // queuine tRNA-ribosyltransferase activity // inferred from sequence or structural similarity /// 0008479 // queuine tRNA-ribosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221271_at NM_021803 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021803.1 /DEF=Homo sapiens interleukin 21 (IL21), mRNA. /FEA=mRNA /GEN=IL21 /PROD=interleukin 21 /DB_XREF=gi:11141874 /UG=Hs.302014 interleukin 21 /FL=gb:AF254069.1 gb:NM_021803.1 NM_021803 interleukin 21 IL21 59067 NM_001207006 /// NM_021803 0002729 // positive regulation of natural killer cell cytokine production // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from direct assay /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0034105 // positive regulation of tissue remodeling // inferred by curator /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0045078 // positive regulation of interferon-gamma biosynthetic process // non-traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0048469 // cell maturation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred by curator 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005125 // cytokine activity // inferred from electronic annotation /// 0005126 // cytokine receptor binding // traceable author statement /// 0005134 // interleukin-2 receptor binding // inferred from physical interaction 221272_s_at NM_030806 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030806.1 /DEF=Homo sapiens chromosome 1 open reading frame 21 (C1ORF21), mRNA. /FEA=mRNA /GEN=C1ORF21 /PROD=chromosome 1 open reading frame 21 /DB_XREF=gi:13540595 /FL=gb:NM_030806.1 NM_030806 chromosome 1 open reading frame 21 C1orf21 81563 NM_030806 221273_s_at NM_031297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031297.1 /DEF=Homo sapiens hypothetical protein DKFZp761H1710 (DKFZP761H1710), mRNA. /FEA=mRNA /GEN=DKFZP761H1710 /PROD=hypothetical protein DKFZp761H1710 /DB_XREF=gi:13775217 /FL=gb:NM_031297.1 NM_031297 ring finger protein 208 RNF208 727800 NM_031297 0051865 // protein autoubiquitination // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221274_s_at NM_030805 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030805.1 /DEF=Homo sapiens hypothetical protein DKFZp564L2423 (DKFZP564L2423), mRNA. /FEA=mRNA /GEN=DKFZP564L2423 /PROD=hypothetical protein DKFZp564L2423 /DB_XREF=gi:13540593 /FL=gb:NM_030805.1 NM_030805 lectin, mannose-binding 2-like LMAN2L 81562 NM_001142292 /// NM_030805 /// NR_024518 /// NR_024519 /// NR_024520 /// NR_024521 /// XM_006712785 0006457 // protein folding // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030134 // ER to Golgi transport vesicle // non-traceable author statement 0005537 // mannose binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221275_s_at NM_030896 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030896.1 /DEF=Homo sapiens hypothetical protein FLJ13520 (FLJ13520), mRNA. /FEA=mRNA /GEN=FLJ13520 /PROD=hypothetical protein FLJ13520 /DB_XREF=gi:13591867 /FL=gb:NM_030896.1 NM_030896 221276_s_at NM_030786 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030786.1 /DEF=Homo sapiens intermediate filament protein syncoilin (SYNCOILIN), mRNA. /FEA=mRNA /GEN=SYNCOILIN /PROD=intermediate filament protein syncoilin /DB_XREF=gi:13540560 /FL=gb:NM_030786.1 NM_030786 syncoilin, intermediate filament protein SYNC 81493 NM_001161708 /// NM_030786 0045103 // intermediate filament-based process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221277_s_at NM_031307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031307.1 /DEF=Homo sapiens hypothetical protein FKSG32 (FKSG32), mRNA. /FEA=mRNA /GEN=FKSG32 /PROD=hypothetical protein FKSG32 /DB_XREF=gi:13775233 /FL=gb:NM_031307.1 NM_031307 pseudouridylate synthase 3 PUS3 83480 NM_001271985 /// NM_031307 /// XM_005271687 /// XM_005271688 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0031119 // tRNA pseudouridine synthesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 221278_at NM_024016 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024016.1 /DEF=Homo sapiens homeo box B8 (HOXB8), mRNA. /FEA=CDS /GEN=HOXB8 /PROD=homeo box B8 /DB_XREF=gi:13273316 /UG=Hs.324916 homeo box B8 /FL=gb:NM_024016.1 NM_024016 homeobox B8 HOXB8 3218 NM_024016 /// XM_005257286 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021516 // dorsal spinal cord development // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221279_at NM_018972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018972.1 /DEF=Homo sapiens ganglioside-induced differentiation-associated protein 1 (GDAP1), mRNA. /FEA=CDS /GEN=GDAP1 /PROD=ganglioside-induced differentiation-associatedprotein 1 /DB_XREF=gi:9506716 /UG=Hs.249223 ganglioside-induced differentiation-associated protein 1 /FL=gb:NM_018972.1 NM_018972 ganglioside induced differentiation associated protein 1 GDAP1 54332 NM_001040875 /// NM_018972 /// NR_046346 /// XM_006716457 0000266 // mitochondrial fission // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221280_s_at NM_019619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019619.1 /DEF=Homo sapiens protease-activated receptor 3 (PAR3), mRNA. /FEA=CDS /GEN=PAR3 /PROD=protease-activated receptor 3 /DB_XREF=gi:9665241 /UG=Hs.72249 three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect) /FL=gb:AF252293.1 gb:NM_019619.1 NM_019619 par-3 family cell polarity regulator PARD3 56288 NM_001184785 /// NM_001184786 /// NM_001184787 /// NM_001184788 /// NM_001184789 /// NM_001184790 /// NM_001184791 /// NM_001184792 /// NM_001184793 /// NM_001184794 /// NM_019619 /// XM_005252528 /// XM_005252530 /// XM_005252531 /// XM_005252532 /// XM_005252534 /// XM_005252535 /// XM_005252536 /// XM_006717471 /// XM_006717472 /// XM_006717473 /// XM_006717474 /// XM_006717475 /// XM_006717476 /// XM_006717477 /// XM_006717478 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0003383 // apical constriction // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008356 // asymmetric cell division // traceable author statement /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0044319 // wound healing, spreading of cells // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060341 // regulation of cellular localization // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0033269 // internode region of axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from sequence or structural similarity 221281_at NM_005417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_005417.1 /DEF=Homo sapiens v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC), mRNA. /FEA=CDS /GEN=SRC /PROD=v-src avian sarcoma (Schmidt-Ruppin A-2) viraloncogene homolog /DB_XREF=gi:4885608 /UG=Hs.198298 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog /FL=gb:NM_005417.1 NM_005417 SRC proto-oncogene, non-receptor tyrosine kinase SRC 6714 NM_005417 /// NM_198291 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0033146 // regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033625 // positive regulation of integrin activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043114 // regulation of vascular permeability // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045124 // regulation of bone resorption // traceable author statement /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048477 // oogenesis // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051895 // negative regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051902 // negative regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0060065 // uterus development // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071393 // cellular response to progesterone stimulus // inferred from sequence or structural similarity /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from physical interaction 221282_x_at NM_004348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004348.1 /DEF=Homo sapiens runt-related transcription factor 2 (RUNX2), mRNA. /FEA=CDS /GEN=RUNX2 /PROD=runt-related transcription factor 2 /DB_XREF=gi:10863884 /UG=Hs.121895 runt-related transcription factor 2 /FL=gb:NM_004348.1 NM_004348 runt-related transcription factor 2 RUNX2 860 NM_001015051 /// NM_001024630 /// NM_001278478 /// NM_004348 /// NR_103532 /// NR_103533 /// XM_006715231 /// XM_006715232 /// XM_006715233 /// XM_006715234 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // traceable author statement /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001649 // osteoblast differentiation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 221283_at NM_004348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004348.1 /DEF=Homo sapiens runt-related transcription factor 2 (RUNX2), mRNA. /FEA=CDS /GEN=RUNX2 /PROD=runt-related transcription factor 2 /DB_XREF=gi:10863884 /UG=Hs.121895 runt-related transcription factor 2 /FL=gb:NM_004348.1 NM_004348 runt-related transcription factor 2 RUNX2 860 NM_001015051 /// NM_001024630 /// NM_001278478 /// NM_004348 /// NR_103532 /// NR_103533 /// XM_006715231 /// XM_006715232 /// XM_006715233 /// XM_006715234 0001503 // ossification // traceable author statement /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001649 // osteoblast differentiation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048469 // cell maturation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 221284_s_at NM_005417 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005417.1 /DEF=Homo sapiens v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC), mRNA. /FEA=CDS /GEN=SRC /PROD=v-src avian sarcoma (Schmidt-Ruppin A-2) viraloncogene homolog /DB_XREF=gi:4885608 /UG=Hs.198298 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog /FL=gb:NM_005417.1 NM_005417 SRC proto-oncogene, non-receptor tyrosine kinase SRC 6714 NM_005417 /// NM_198291 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0033146 // regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033625 // positive regulation of integrin activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043114 // regulation of vascular permeability // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045124 // regulation of bone resorption // traceable author statement /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048477 // oogenesis // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051895 // negative regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051902 // negative regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0060065 // uterus development // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071393 // cellular response to progesterone stimulus // inferred from sequence or structural similarity /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from physical interaction 221285_at NM_006011 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006011.1 /DEF=Homo sapiens sialyltransferase 8 (alpha-2, 8-sialytransferase) B (SIAT8B), mRNA. /FEA=CDS /GEN=SIAT8B /PROD=sialyltransferase 8 (alpha-2,8-sialytransferase) B /DB_XREF=gi:5174676 /UG=Hs.247841 sialyltransferase 8 (alpha-2, 8-sialytransferase) B /FL=gb:U82762.1 gb:NM_006011.1 gb:U33551.1 NM_006011 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8SIA2 8128 NM_006011 0001574 // ganglioside biosynthetic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from direct assay /// 0006491 // N-glycan processing // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation 0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred by curator 221286_s_at NM_016459 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016459.1 /DEF=Homo sapiens hypothetical protein (LOC51237), mRNA. /FEA=CDS /GEN=LOC51237 /PROD=hypothetical protein /DB_XREF=gi:7706002 /UG=Hs.122492 hypothetical protein /FL=gb:NM_016459.1 NM_016459 marginal zone B and B1 cell-specific protein MZB1 51237 NM_016459 0002642 // positive regulation of immunoglobulin biosynthetic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030888 // regulation of B cell proliferation // inferred from sequence or structural similarity /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 2001274 // negative regulation of glucose import in response to insulin stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from sequence or structural similarity /// 0034663 // endoplasmic reticulum chaperone complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 221287_at NM_021133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021133.1 /DEF=Homo sapiens ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) (RNASEL), mRNA. /FEA=CDS /GEN=RNASEL /PROD=ribonuclease L (2,5-oligoisoadenylatesynthetase-dependent) /DB_XREF=gi:10863928 /UG=Hs.249230 ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) /FL=gb:NM_021133.1 NM_021133 ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) RNASEL 6041 NM_021133 /// XM_005245411 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004521 // endoribonuclease activity // non-traceable author statement /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221288_at NM_005295 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005295.1 /DEF=Homo sapiens G protein-coupled receptor 22 (GPR22), mRNA. /FEA=CDS /GEN=GPR22 /PROD=G protein-coupled receptor 22 /DB_XREF=gi:4885308 /UG=Hs.248121 G protein-coupled receptor 22 /FL=gb:NM_005295.1 NM_005295 G protein-coupled receptor 22 GPR22 2845 NM_005295 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221289_at NM_005222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005222.1 /DEF=Homo sapiens distal-less homeo box 6 (DLX6), mRNA. /FEA=CDS /GEN=DLX6 /PROD=distal-less homeo box 6 /DB_XREF=gi:4885188 /UG=Hs.249196 distal-less homeo box 6 /FL=gb:NM_005222.1 NM_005222 distal-less homeobox 6 DLX6 1750 NM_005222 0001501 // skeletal system development // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060322 // head development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221290_s_at NM_016473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016473.1 /DEF=Homo sapiens hypothetical protein (LOC51243), mRNA. /FEA=CDS /GEN=LOC51243 /PROD=hypothetical protein /DB_XREF=gi:7706014 /UG=Hs.267263 hypothetical protein /FL=gb:NM_016473.1 NM_016473 melanoma associated antigen (mutated) 1 MUM1 84939 NM_032853 /// NR_024247 0006281 // DNA repair // inferred from mutant phenotype /// 0006325 // chromatin organization // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from direct assay 221291_at NM_025217 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025217.1 /DEF=Homo sapiens UL16-binding protein 2 (ULBP2), mRNA. /FEA=CDS /GEN=ULBP2 /PROD=UL16-binding protein 2 /DB_XREF=gi:13376823 /UG=Hs.250618 UL16-binding protein 2 /FL=gb:AF304378.1 gb:NM_025217.1 NM_025217 UL16 binding protein 2 ULBP2 80328 NM_025217 /// XM_005267150 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0030101 // natural killer cell activation // inferred from direct assay /// 0042267 // natural killer cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from direct assay 0003823 // antigen binding // not recorded /// 0046703 // natural killer cell lectin-like receptor binding // inferred from direct assay 221292_at NM_003738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003738.1 /DEF=Homo sapiens patched (Drosophila) homolog 2 (PTCH2), mRNA. /FEA=CDS /GEN=PTCH2 /PROD=patched (Drosophila) homolog 2 /DB_XREF=gi:4506244 /UG=Hs.249164 patched (Drosophila) homolog 2 /FL=gb:AF091501.1 gb:AF119569.1 gb:NM_003738.1 gb:AF087651.1 NM_003738 patched 2 PTCH2 8643 NM_001166292 /// NM_003738 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0042633 // hair cycle // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005119 // smoothened binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // traceable author statement /// 0097108 // hedgehog family protein binding // inferred from physical interaction /// 0097108 // hedgehog family protein binding // traceable author statement 221293_s_at NM_022047 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022047.1 /DEF=Homo sapiens differentially expressed in FDCP (mouse homolog) 6 (DEF6), mRNA. /FEA=CDS /GEN=DEF6 /PROD=differentially expressed in FDCP (mouse homolog)6 /DB_XREF=gi:11545748 /UG=Hs.15476 differentially expressed in FDCP (mouse homolog) 6 /FL=gb:NM_022047.1 NM_022047 differentially expressed in FDCP 6 homolog (mouse) DEF6 50619 NM_022047 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 221294_at NM_005294 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005294.1 /DEF=Homo sapiens G protein-coupled receptor 21 (GPR21), mRNA. /FEA=CDS /GEN=GPR21 /PROD=G protein-coupled receptor 21 /DB_XREF=gi:4885306 /UG=Hs.248120 G protein-coupled receptor 21 /FL=gb:NM_005294.1 NM_005294 G protein-coupled receptor 21 GPR21 2844 NM_005294 /// XM_005251933 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221295_at NM_001279 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001279.1 /DEF=Homo sapiens cell death-inducing DFFA-like effector a (CIDEA), mRNA. /FEA=CDS /GEN=CIDEA /PROD=cell death-inducing DFFA-like effector a /DB_XREF=gi:4557464 /UG=Hs.249129 cell death-inducing DFFA-like effector a /FL=gb:AF041378.1 gb:NM_001279.1 NM_001279 cell death-inducing DFFA-like effector a CIDEA 1149 NM_001279 /// NR_036468 /// XM_006722297 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008219 // cell death // inferred from sequence or structural similarity /// 0010890 // positive regulation of sequestering of triglyceride // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from mutant phenotype /// 0050995 // negative regulation of lipid catabolic process // inferred from mutant phenotype /// 0050995 // negative regulation of lipid catabolic process // inferred from sequence or structural similarity /// 1900118 // negative regulation of execution phase of apoptosis // inferred from sequence or structural similarity /// 1902510 // regulation of apoptotic DNA fragmentation // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005740 // mitochondrial envelope // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 221296_at NM_005422 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005422.1 /DEF=Homo sapiens tectorin alpha (TECTA), mRNA. /FEA=CDS /GEN=TECTA /PROD=tectorin alpha precursor /DB_XREF=gi:4885626 /UG=Hs.248162 tectorin alpha /FL=gb:NM_005422.1 NM_005422 tectorin alpha TECTA 7007 NM_005422 /// XM_005271653 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221297_at NM_018654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018654.1 /DEF=Homo sapiens G protein-coupled receptor, family C, group 5, member D (GPRC5D), mRNA. /FEA=CDS /GEN=GPRC5D /PROD=G protein-coupled receptor, family C, group 5,member D /DB_XREF=gi:8923704 /UG=Hs.283073 G protein-coupled receptor, family C, group 5, member D /FL=gb:AF209923.1 gb:NM_018654.1 NM_018654 G protein-coupled receptor, class C, group 5, member D GPRC5D 55507 NM_018654 /// XM_005253421 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221298_s_at NM_004254 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004254.1 /DEF=Homo sapiens solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), mRNA. /FEA=CDS /GEN=SLC22A8 /PROD=solute carrier family 22 (organic aniontransporter), member 8 /DB_XREF=gi:4758845 /UG=Hs.266223 solute carrier family 22 (organic anion transporter), member 8 /FL=gb:AF097491.1 gb:NM_004254.1 NM_004254 solute carrier family 22 (organic anion transporter), member 8 SLC22A8 9376 NM_001184732 /// NM_001184733 /// NM_001184736 /// NM_004254 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0015697 // quaternary ammonium group transport // inferred from electronic annotation /// 0015711 // organic anion transport // inferred from electronic annotation /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034635 // glutathione transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from direct assay /// 0008514 // organic anion transmembrane transporter activity // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015651 // quaternary ammonium group transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 221299_at NM_018969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018969.1 /DEF=Homo sapiens super conserved receptor expressed in brain 3 (SREB3), mRNA. /FEA=CDS /GEN=SREB3 /PROD=super conserved receptor expressed in brain 3 /DB_XREF=gi:9507142 /UG=Hs.283023 super conserved receptor expressed in brain 3 /FL=gb:AB040801.1 gb:NM_018969.1 NM_018969 G protein-coupled receptor 173 GPR173 54328 NM_018969 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0097211 // cellular response to gonadotropin-releasing hormone // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004968 // gonadotropin-releasing hormone receptor activity // inferred from electronic annotation 221300_at NM_018958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018958.1 /DEF=Homo sapiens chromosome 15 open reading frame 2 (C15ORF2), mRNA. /FEA=CDS /GEN=C15ORF2 /PROD=chromosome 15 open reading frame 2 /DB_XREF=gi:9506430 /UG=Hs.283013 chromosome 15 open reading frame 2 /FL=gb:NM_018958.1 NM_018958 nuclear pore associated protein 1 NPAP1 23742 NM_018958 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221301_at NM_025258 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025258.1 /DEF=Homo sapiens NG37 protein (G7C), mRNA. /FEA=CDS /GEN=G7C /PROD=NG37 protein /DB_XREF=gi:13376861 /UG=Hs.283875 NG37 protein /FL=gb:NM_025258.1 NM_025258 von Willebrand factor A domain containing 7 VWA7 80737 NM_025258 /// XM_005249427 /// XM_005249428 /// XM_005249429 /// XM_005272904 /// XM_005272905 /// XM_005272906 /// XM_005274894 /// XM_005274895 /// XM_005274896 /// XM_005275059 /// XM_005275060 /// XM_005275061 /// XM_005275316 /// XM_005275317 /// XM_005275318 /// XM_005275620 /// XM_005275621 /// XM_005275622 /// XM_006715220 /// XM_006725050 /// XM_006725529 /// XM_006725748 /// XM_006725944 /// XM_006726133 0005576 // extracellular region // inferred from electronic annotation 221302_at NM_014079 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014079.1 /DEF=Homo sapiens kidney-enriched Kruppel-like factor (KKLF), mRNA. /FEA=CDS /GEN=KKLF /PROD=kidney-enriched Kruppel-like factor /DB_XREF=gi:7662493 /UG=Hs.272215 Kruppel-like factor 15 /FL=gb:AB029254.1 gb:NM_014079.1 NM_014079 Kruppel-like factor 15 KLF15 28999 NM_014079 /// XM_005247400 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 1901653 // cellular response to peptide // inferred from electronic annotation /// 2000757 // negative regulation of peptidyl-lysine acetylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221303_at NM_013340 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013340.1 /DEF=Homo sapiens protocadherin beta 1 (PCDHB1), mRNA. /FEA=CDS /GEN=PCDHB1 /PROD=protocadherin beta 1 /DB_XREF=gi:7019480 /UG=Hs.278950 protocadherin beta 1 /FL=gb:AF152488.1 gb:NM_013340.1 NM_013340 protocadherin beta 1 PCDHB1 29930 NM_013340 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 221304_at NM_019076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019076.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A8 (UGT1A8), mRNA. /FEA=CDS /GEN=UGT1A8 /PROD=UDP glycosyltransferase 1 family, polypeptideA8 /DB_XREF=gi:9507232 /UG=Hs.278741 UDP glycosyltransferase 1 family, polypeptide A8 /FL=gb:NM_019076.1 NM_019076 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A3 /// UDP glucuronosyltransferase 1 family, polypeptide A5 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A3 /// UGT1A5 /// UGT1A8 /// UGT1A9 54576 /// 54579 /// 54600 /// 54658 /// 54659 NM_000463 /// NM_019076 /// NM_019078 /// NM_019093 /// NM_021027 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred by curator /// 0001972 // retinoic acid binding // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred by curator /// 0019899 // enzyme binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 221305_s_at NM_019076 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019076.1 /DEF=Homo sapiens UDP glycosyltransferase 1 family, polypeptide A8 (UGT1A8), mRNA. /FEA=CDS /GEN=UGT1A8 /PROD=UDP glycosyltransferase 1 family, polypeptideA8 /DB_XREF=gi:9507232 /UG=Hs.278741 UDP glycosyltransferase 1 family, polypeptide A8 /FL=gb:NM_019076.1 NM_019076 UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A3 /// UDP glucuronosyltransferase 1 family, polypeptide A5 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9 UGT1A1 /// UGT1A3 /// UGT1A5 /// UGT1A8 /// UGT1A9 54576 /// 54579 /// 54600 /// 54658 /// 54659 NM_000463 /// NM_019076 /// NM_019078 /// NM_019093 /// NM_021027 0001889 // liver development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred by curator /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006789 // bilirubin conjugation // traceable author statement /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007586 // digestion // non-traceable author statement /// 0007588 // excretion // inferred by curator /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred by curator /// 0008210 // estrogen metabolic process // traceable author statement /// 0009804 // coumarin metabolic process // inferred by curator /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred by curator /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042167 // heme catabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred by curator /// 0042594 // response to starvation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045922 // negative regulation of fatty acid metabolic process // inferred by curator /// 0045922 // negative regulation of fatty acid metabolic process // inferred from direct assay /// 0045939 // negative regulation of steroid metabolic process // inferred by curator /// 0046483 // heterocycle metabolic process // inferred by curator /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051552 // flavone metabolic process // inferred from direct assay /// 0052695 // cellular glucuronidation // inferred from direct assay /// 0052695 // cellular glucuronidation // traceable author statement /// 0052696 // flavonoid glucuronidation // inferred from direct assay /// 0052697 // xenobiotic glucuronidation // inferred from direct assay /// 0070980 // biphenyl catabolic process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2001030 // negative regulation of cellular glucuronidation // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070069 // cytochrome complex // inferred from electronic annotation 0001972 // retinoic acid binding // inferred by curator /// 0001972 // retinoic acid binding // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from direct assay /// 0005496 // steroid binding // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0008144 // drug binding // inferred by curator /// 0008194 // UDP-glycosyltransferase activity // traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from electronic annotation /// 0015020 // glucuronosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred by curator /// 0019899 // enzyme binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 221306_at NM_018971 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018971.1 /DEF=Homo sapiens G protein-coupled receptor 27 (GPR27), mRNA. /FEA=CDS /GEN=GPR27 /PROD=super conserved receptor expressed in brain 1 /DB_XREF=gi:9506746 /UG=Hs.278283 G protein-coupled receptor 27 /FL=gb:AB040799.1 gb:NM_018971.1 NM_018971 G protein-coupled receptor 27 GPR27 2850 NM_018971 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221307_at NM_014592 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014592.1 /DEF=Homo sapiens Kv channel-interacting protein 1 (KCNIP1), mRNA. /FEA=CDS /GEN=KCNIP1 /PROD=Kv channel-interacting protein 1 /DB_XREF=gi:7657246 /UG=Hs.130522 Kv channel-interacting protein 1 /FL=gb:AF199597.1 gb:NM_014592.1 NM_014592 Kv channel interacting protein 1 KCNIP1 30820 NM_001034837 /// NM_001034838 /// NM_001278339 /// NM_001278340 /// NM_014592 /// XM_006714861 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0045760 // positive regulation of action potential // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0034705 // potassium channel complex // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 221308_at NM_006654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006654.1 /DEF=Homo sapiens suc1-associated neurotrophic factor target (FGFR signalling adaptor) (SNT-1), mRNA. /FEA=CDS /GEN=SNT-1 /PROD=suc1-associated neurotrophic factor target (FGFRsignalling adaptor) /DB_XREF=gi:5730056 /UG=Hs.251394 suc1-associated neurotrophic factor target (FGFR signalling adaptor) /FL=gb:AF036717.1 gb:NM_006654.1 NM_006654 fibroblast growth factor receptor substrate 2 FRS2 10818 NM_001042555 /// NM_001278351 /// NM_001278353 /// NM_001278354 /// NM_001278355 /// NM_001278356 /// NM_001278357 /// NM_006654 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008595 // anterior/posterior axis specification, embryo // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046619 // optic placode formation involved in camera-type eye formation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement /// 0005104 // fibroblast growth factor receptor binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // traceable author statement 221309_at NM_006450 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006450.1 /DEF=Homo sapiens splicing factor (45kD) (SPF45), mRNA. /FEA=CDS /GEN=SPF45 /PROD=splicing factor (45kD) /DB_XREF=gi:5454081 /UG=Hs.209450 splicing factor (45kD) /FL=gb:AF083384.1 gb:NM_006450.1 NM_006450 RNA binding motif protein 17 RBM17 84991 NM_001145547 /// NM_032905 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221310_at NM_004115 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004115.1 /DEF=Homo sapiens fibroblast growth factor 14 (FGF14), mRNA. /FEA=CDS /GEN=FGF14 /PROD=fibroblast growth factor 14 /DB_XREF=gi:4758367 /UG=Hs.197757 fibroblast growth factor 14 /FL=gb:U66200.1 gb:NM_004115.1 NM_004115 fibroblast growth factor 14 FGF14 2259 NM_004115 /// NM_175929 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // inferred from physical interaction /// 0007267 // cell-cell signaling // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay 221311_x_at NM_020466 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020466.1 /DEF=Homo sapiens hypothetical protein dJ122O8.2 (DJ122O8.2), mRNA. /FEA=CDS /GEN=DJ122O8.2 /PROD=hypothetical protein dJ122O8.2 /DB_XREF=gi:10092688 /UG=Hs.132094 hypothetical protein dJ122O8.2 /FL=gb:NM_020466.1 NM_020466 LYR motif containing 2 LYRM2 57226 NM_020466 /// NR_028493 /// NR_028494 /// NR_028495 0005739 // mitochondrion // inferred from electronic annotation 221312_at NM_004246 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004246.1 /DEF=Homo sapiens glucagon-like peptide 2 receptor (GLP2R), mRNA. /FEA=CDS /GEN=GLP2R /PROD=glucagon-like peptide 2 receptor precursor /DB_XREF=gi:4758437 /UG=Hs.248202 glucagon-like peptide 2 receptor /FL=gb:AF105367.1 gb:NM_004246.1 NM_004246 glucagon-like peptide 2 receptor GLP2R 9340 NM_004246 /// XM_005256861 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0071377 // cellular response to glucagon stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004967 // glucagon receptor activity // inferred from electronic annotation 221313_at NM_005684 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005684.1 /DEF=Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA. /FEA=CDS /GEN=GPR52 /PROD=G protein-coupled receptor 52 /DB_XREF=gi:5031720 /UG=Hs.247718 G protein-coupled receptor 52 /FL=gb:NM_005684.1 NM_005684 G protein-coupled receptor 52 GPR52 9293 NM_005684 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221314_at NM_005260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005260.2 /DEF=Homo sapiens growth differentiation factor 9 (GDF9), mRNA. /FEA=CDS /GEN=GDF9 /PROD=growth differentiation factor 9 precursor /DB_XREF=gi:6715598 /UG=Hs.248113 growth differentiation factor 9 /FL=gb:NM_005260.2 NM_005260 growth differentiation factor 9 GDF9 2661 NM_001288824 /// NM_001288825 /// NM_001288826 /// NM_001288827 /// NM_001288828 /// NM_005260 /// XM_005271957 /// XM_006714585 0001555 // oocyte growth // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 2000870 // regulation of progesterone secretion // inferred from direct assay /// 2000870 // regulation of progesterone secretion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221315_s_at NM_020637 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020637.1 /DEF=Homo sapiens fibroblast growth factor 22 (FGF22), mRNA. /FEA=CDS /GEN=FGF22 /PROD=fibroblast growth factor 22 /DB_XREF=gi:10190671 /UG=Hs.248087 fibroblast growth factor 22 /FL=gb:AB021925.1 gb:NM_020637.1 NM_020637 fibroblast growth factor 22 FGF22 27006 NM_020637 /// XM_005259538 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221316_at NM_021185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021185.1 /DEF=Homo sapiens hypothetical protein DKFZp434A1022 (DKFZP434A1022), mRNA. /FEA=CDS /GEN=DKFZP434A1022 /PROD=hypothetical protein DKFZp434A1022 /DB_XREF=gi:11024715 /UG=Hs.324335 hypothetical protein DKFZp434A1022 /FL=gb:NM_021185.1 NM_021185 catsper channel auxiliary subunit gamma CATSPERG 57828 NM_021185 /// XM_005259114 /// XM_005259115 /// XM_005259116 /// XM_005259117 /// XM_005259118 /// XM_006723308 /// XM_006723309 /// XM_006723310 /// XM_006723311 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0035036 // sperm-egg recognition // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0036128 // CatSper complex // inferred from sequence or structural similarity /// 0097228 // sperm principal piece // inferred from electronic annotation 221317_x_at NM_018939 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018939.1 /DEF=Homo sapiens protocadherin beta 6 (PCDHB6), mRNA. /FEA=CDS /GEN=PCDHB6 /PROD=protocadherin beta 6 /DB_XREF=gi:9256617 /UG=Hs.283085 protocadherin beta 6 /FL=gb:AF152499.1 gb:NM_018939.1 NM_018939 protocadherin beta 6 PCDHB6 56130 NM_018939 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 221318_at NM_021191 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021191.1 /DEF=Homo sapiens neurogenic differentiation 4 (NEUROD4), mRNA. /FEA=CDS /GEN=NEUROD4 /PROD=neurogenic differentiation 4 /DB_XREF=gi:10863998 /UG=Hs.302013 neurogenic differentiation 4 /FL=gb:NM_021191.1 NM_021191 neuronal differentiation 4 NEUROD4 58158 NM_021191 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0010001 // glial cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035881 // amacrine cell differentiation // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 221319_at NM_019120 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019120.1 /DEF=Homo sapiens protocadherin beta 8 (PCDHB8), mRNA. /FEA=CDS /GEN=PCDHB8 /PROD=protocadherin beta 8 /DB_XREF=gi:11276080 /UG=Hs.287793 protocadherin beta 8 /FL=gb:AF152501.2 gb:NM_019120.1 NM_019120 protocadherin beta 8 PCDHB8 56128 NM_019120 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 221320_at NM_020396 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020396.1 /DEF=Homo sapiens BCL2-like 10 (apoptosis facilitator) (BCL2L10), mRNA. /FEA=CDS /GEN=BCL2L10 /PROD=BCL2-like 10 (apoptosis facilitator) /DB_XREF=gi:9966782 /UG=Hs.283672 BCL2-like 10 (apoptosis facilitator) /FL=gb:AF285092.1 gb:NM_020396.1 NM_020396 BCL2-like 10 (apoptosis facilitator) BCL2L10 10017 NM_020396 /// XM_005254103 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // not recorded 221321_s_at NM_014591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014591.1 /DEF=Homo sapiens Kv channel-interacting protein 2 (KCNIP2), mRNA. /FEA=CDS /GEN=KCNIP2 /PROD=Kv channel-interacting protein 2 /DB_XREF=gi:7657248 /UG=Hs.97044 Kv channel-interacting protein 2 /FL=gb:AF199598.1 gb:NM_014591.1 NM_014591 Kv channel interacting protein 2 KCNIP2 30819 NM_014591 /// NM_173191 /// NM_173192 /// NM_173193 /// NM_173194 /// NM_173195 /// NM_173197 /// NM_173342 /// XM_005269729 /// XM_005269730 /// XM_006717812 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006936 // muscle contraction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0045163 // clustering of voltage-gated potassium channels // inferred from direct assay /// 0071435 // potassium ion export // inferred from direct assay /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086009 // membrane repolarization // inferred from direct assay /// 2001257 // regulation of cation channel activity // traceable author statement 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005250 // A-type (transient outward) potassium channel activity // inferred from direct assay /// 0005250 // A-type (transient outward) potassium channel activity // traceable author statement /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046923 // ER retention sequence binding // non-traceable author statement /// 0047485 // protein N-terminus binding // inferred from physical interaction 221322_at NM_022150 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022150.1 /DEF=Homo sapiens RFamide-related peptide precursor (RFRP), mRNA. /FEA=CDS /GEN=RFRP /PROD=RFamide-related peptide precursor /DB_XREF=gi:11545893 /UG=Hs.60473 RFamide-related peptide precursor /FL=gb:AB040290.1 gb:NM_022150.1 NM_022150 neuropeptide VF precursor NPVF 64111 NM_022150 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0032277 // negative regulation of gonadotropin secretion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement 0004930 // G-protein coupled receptor activity // non-traceable author statement 221323_at NM_025218 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025218.1 /DEF=Homo sapiens UL16-binding protein 1 (ULBP1), mRNA. /FEA=CDS /GEN=ULBP1 /PROD=UL16-binding protein 1 /DB_XREF=gi:13376825 /UG=Hs.326559 UL16-binding protein 1 /FL=gb:AF304377.1 gb:NM_025218.1 NM_025218 UL16 binding protein 1 ULBP1 80329 NM_025218 /// XM_005267151 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // not recorded /// 0030101 // natural killer cell activation // inferred from direct assay /// 0042267 // natural killer cell mediated cytotoxicity // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from direct assay 0003823 // antigen binding // not recorded /// 0046703 // natural killer cell lectin-like receptor binding // inferred from direct assay 221324_at NM_019599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019599.1 /DEF=Homo sapiens taste receptor, type 2, member 1 (TAS2R1), mRNA. /FEA=CDS /GEN=TAS2R1 /PROD=taste receptor T2R1 /DB_XREF=gi:9625042 /UG=Hs.168278 taste receptor, type 2, member 1 /FL=gb:NM_019599.1 NM_019599 taste receptor, type 2, member 1 TAS2R1 50834 NM_019599 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007635 // chemosensory behavior // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221325_at NM_022054 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022054.1 /DEF=Homo sapiens reserved (KCNK13), mRNA. /FEA=CDS /GEN=KCNK13 /PROD=tandem pore domain potassium channel THIK-1 /DB_XREF=gi:11545758 /UG=Hs.302012 potassium channel, subfamily K, member 13 (THIK-1) /FL=gb:AF287303.1 gb:NM_022054.1 NM_022054 potassium channel, subfamily K, member 13 KCNK13 56659 NM_022054 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // traceable author statement 221326_s_at NM_016261 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016261.1 /DEF=Homo sapiens delta-tubulin (LOC51174), mRNA. /FEA=CDS /GEN=LOC51174 /PROD=delta-tubulin /DB_XREF=gi:7705912 /UG=Hs.270847 delta-tubulin /FL=gb:AF201333.1 gb:NM_016261.1 NM_016261 tubulin, delta 1 TUBD1 51174 NM_001193609 /// NM_001193610 /// NM_001193611 /// NM_001193612 /// NM_001193613 /// NM_016261 /// XM_005257425 /// XM_005257426 /// XM_005257427 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 221327_s_at NM_000513 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000513.1 /DEF=Homo sapiens opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) (OPN1MW), mRNA. /FEA=CDS /GEN=OPN1MW /PROD=opsin 1 (cone pigments), medium-wave-sensitive(color blindness, deutan) /DB_XREF=gi:4503964 /UG=Hs.282279 opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) /FL=gb:NM_000513.1 NM_000513 medium-wave-sensitive opsin 1-like /// opsin 1 (cone pigments), long-wave-sensitive /// opsin 1 (cone pigments), medium-wave-sensitive /// opsin 1 (cone pigments), medium-wave-sensitive 2 LOC101060233 /// OPN1LW /// OPN1MW /// OPN1MW2 2652 /// 5956 /// 728458 /// 101060233 NM_000513 /// NM_001048181 /// NM_020061 /// XM_003960089 /// XM_005276725 0001523 // retinoid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0018298 // protein-chromophore linkage // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0009881 // photoreceptor activity // inferred from electronic annotation 221328_at NM_012131 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012131.1 /DEF=Homo sapiens claudin 17 (CLDN17), mRNA. /FEA=CDS /GEN=CLDN17 /PROD=claudin 17 /DB_XREF=gi:6912315 /UG=Hs.258589 claudin 17 /FL=gb:NM_012131.1 NM_012131 claudin 17 CLDN17 26285 NM_012131 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 221329_at NM_012375 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012375.1 /DEF=Homo sapiens olfactory receptor, family 52, subfamily A, member 1 (OR52A1), mRNA. /FEA=CDS /GEN=OR52A1 /PROD=olfactory receptor, family 52, subfamily A,member 1 /DB_XREF=gi:6912559 /UG=Hs.258582 olfactory receptor, family 52, subfamily A, member 1 /FL=gb:NM_012375.1 NM_012375 olfactory receptor, family 52, subfamily A, member 1 OR52A1 23538 NM_012375 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221330_at NM_000739 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000739.1 /DEF=Homo sapiens cholinergic receptor, muscarinic 2 (CHRM2), mRNA. /FEA=CDS /GEN=CHRM2 /PROD=cholinergic receptor, muscarinic 2 /DB_XREF=gi:4502816 /UG=Hs.248099 cholinergic receptor, muscarinic 2 /FL=gb:NM_000739.1 NM_000739 cholinergic receptor, muscarinic 2 CHRM2 1129 NM_000739 /// NM_001006626 /// NM_001006627 /// NM_001006628 /// NM_001006629 /// NM_001006630 /// NM_001006631 /// NM_001006632 /// NM_001006633 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007207 // phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016907 // G-protein coupled acetylcholine receptor activity // inferred from electronic annotation 221331_x_at NM_005214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005214.1 /DEF=Homo sapiens cytotoxic T-lymphocyte-associated protein 4 (CTLA4), mRNA. /FEA=CDS /GEN=CTLA4 /PROD=cytotoxic T-lymphocyte-associated protein 4 /DB_XREF=gi:4885166 /UG=Hs.247824 cytotoxic T-lymphocyte-associated protein 4 /FL=gb:NM_005214.1 NM_005214 cytotoxic T-lymphocyte-associated protein 4 CTLA4 1493 NM_001037631 /// NM_005214 /// XR_241294 /// XR_427072 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0030889 // negative regulation of B cell proliferation // inferred from mutant phenotype /// 0031295 // T cell costimulation // traceable author statement /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045590 // negative regulation of regulatory T cell differentiation // inferred from direct assay /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221332_at NM_005448 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005448.1 /DEF=Homo sapiens bone morphogenetic protein 15 (BMP15), mRNA. /FEA=CDS /GEN=BMP15 /PROD=bone morphogenetic protein 15 precursor /DB_XREF=gi:4885096 /UG=Hs.247820 bone morphogenetic protein 15 /FL=gb:NM_005448.1 NM_005448 bone morphogenetic protein 15 BMP15 9210 NM_005448 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060016 // granulosa cell development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221333_at NM_014009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014009.1 /DEF=Homo sapiens immunodeficiency, polyendocrinopathy, enteropathy, X-linked (IPEX), mRNA. /FEA=CDS /GEN=IPEX /PROD=JM2 protein /DB_XREF=gi:7661845 /UG=Hs.247700 immunodeficiency, polyendocrinopathy, enteropathy, X-linked /FL=gb:AJ005891.1 gb:NM_014009.1 NM_014009 forkhead box P3 FOXP3 50943 NM_001114377 /// NM_014009 /// XM_005272610 /// XM_005272611 /// XM_006724533 0001782 // B cell homeostasis // not recorded /// 0001816 // cytokine production // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // not recorded /// 0002262 // myeloid cell homeostasis // not recorded /// 0002329 // pre-B cell differentiation // not recorded /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0002507 // tolerance induction // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // not recorded /// 0002637 // regulation of immunoglobulin production // inferred from electronic annotation /// 0002639 // positive regulation of immunoglobulin production // not recorded /// 0002666 // positive regulation of T cell tolerance induction // inferred from electronic annotation /// 0002669 // positive regulation of T cell anergy // not recorded /// 0002677 // negative regulation of chronic inflammatory response // not recorded /// 0002725 // negative regulation of T cell cytokine production // inferred from direct assay /// 0002851 // positive regulation of peripheral T cell tolerance induction // not recorded /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007519 // skeletal muscle tissue development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from expression pattern /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030324 // lung development // not recorded /// 0031064 // negative regulation of histone deacetylation // inferred from genetic interaction /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032693 // negative regulation of interleukin-10 production // inferred from direct assay /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0032713 // negative regulation of interleukin-4 production // inferred from direct assay /// 0032714 // negative regulation of interleukin-5 production // not recorded /// 0032715 // negative regulation of interleukin-6 production // not recorded /// 0032720 // negative regulation of tumor necrosis factor production // not recorded /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from direct assay /// 0032831 // positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // not recorded /// 0032914 // positive regulation of transforming growth factor beta1 production // not recorded /// 0033092 // positive regulation of immature T cell proliferation in thymus // not recorded /// 0033152 // immunoglobulin V(D)J recombination // not recorded /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // not recorded /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0043029 // T cell homeostasis // non-traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045077 // negative regulation of interferon-gamma biosynthetic process // not recorded /// 0045085 // negative regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046007 // negative regulation of activated T cell proliferation // non-traceable author statement /// 0048294 // negative regulation of isotype switching to IgE isotypes // not recorded /// 0048302 // regulation of isotype switching to IgG isotypes // not recorded /// 0048745 // smooth muscle tissue development // not recorded /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // not recorded /// 0050710 // negative regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // not recorded /// 0055007 // cardiac muscle cell differentiation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0043234 // protein complex // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // not recorded /// 0051059 // NF-kappaB binding // non-traceable author statement /// 0051525 // NFAT protein binding // inferred from physical interaction 221334_s_at NM_014009 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014009.1 /DEF=Homo sapiens immunodeficiency, polyendocrinopathy, enteropathy, X-linked (IPEX), mRNA. /FEA=CDS /GEN=IPEX /PROD=JM2 protein /DB_XREF=gi:7661845 /UG=Hs.247700 immunodeficiency, polyendocrinopathy, enteropathy, X-linked /FL=gb:AJ005891.1 gb:NM_014009.1 NM_014009 forkhead box P3 FOXP3 50943 NM_001114377 /// NM_014009 /// XM_005272610 /// XM_005272611 /// XM_006724533 0001782 // B cell homeostasis // not recorded /// 0001816 // cytokine production // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // not recorded /// 0002262 // myeloid cell homeostasis // not recorded /// 0002329 // pre-B cell differentiation // not recorded /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0002507 // tolerance induction // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // not recorded /// 0002637 // regulation of immunoglobulin production // inferred from electronic annotation /// 0002639 // positive regulation of immunoglobulin production // not recorded /// 0002666 // positive regulation of T cell tolerance induction // inferred from electronic annotation /// 0002669 // positive regulation of T cell anergy // not recorded /// 0002677 // negative regulation of chronic inflammatory response // not recorded /// 0002725 // negative regulation of T cell cytokine production // inferred from direct assay /// 0002851 // positive regulation of peripheral T cell tolerance induction // not recorded /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007519 // skeletal muscle tissue development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from expression pattern /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030324 // lung development // not recorded /// 0031064 // negative regulation of histone deacetylation // inferred from genetic interaction /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032693 // negative regulation of interleukin-10 production // inferred from direct assay /// 0032703 // negative regulation of interleukin-2 production // inferred from direct assay /// 0032713 // negative regulation of interleukin-4 production // inferred from direct assay /// 0032714 // negative regulation of interleukin-5 production // not recorded /// 0032715 // negative regulation of interleukin-6 production // not recorded /// 0032720 // negative regulation of tumor necrosis factor production // not recorded /// 0032753 // positive regulation of interleukin-4 production // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from direct assay /// 0032831 // positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // not recorded /// 0032914 // positive regulation of transforming growth factor beta1 production // not recorded /// 0033092 // positive regulation of immature T cell proliferation in thymus // not recorded /// 0033152 // immunoglobulin V(D)J recombination // not recorded /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // not recorded /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042130 // negative regulation of T cell proliferation // inferred from direct assay /// 0043029 // T cell homeostasis // non-traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045077 // negative regulation of interferon-gamma biosynthetic process // not recorded /// 0045085 // negative regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045591 // positive regulation of regulatory T cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046007 // negative regulation of activated T cell proliferation // non-traceable author statement /// 0048294 // negative regulation of isotype switching to IgE isotypes // not recorded /// 0048302 // regulation of isotype switching to IgG isotypes // not recorded /// 0048745 // smooth muscle tissue development // not recorded /// 0050672 // negative regulation of lymphocyte proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // not recorded /// 0050710 // negative regulation of cytokine secretion // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // not recorded /// 0055007 // cardiac muscle cell differentiation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0043234 // protein complex // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // not recorded /// 0051059 // NF-kappaB binding // non-traceable author statement /// 0051525 // NFAT protein binding // inferred from physical interaction 221335_x_at NM_019108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019108.1 /DEF=Homo sapiens hypothetical protein F17127_1 (F17127_1), mRNA. /FEA=CDS /GEN=F17127_1 /PROD=hypothetical protein F17127_1 /DB_XREF=gi:10092658 /UG=Hs.10116 hypothetical protein F17127_1 /FL=gb:NM_019108.1 NM_019108 SMG9 nonsense mediated mRNA decay factor SMG9 56006 NM_019108 /// XM_005259057 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 221336_at NM_005172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005172.1 /DEF=Homo sapiens atonal homolog 1 (Drosophila) (ATOH1), mRNA. /FEA=CDS /GEN=ATOH1 /PROD=atonal (Drosophila) homolog 1 /DB_XREF=gi:4885074 /UG=Hs.247685 atonal homolog 1 (Drosophila) /FL=gb:NM_005172.1 NM_005172 atonal homolog 1 (Drosophila) ATOH1 474 NM_005172 0001764 // neuron migration // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042667 // auditory receptor cell fate specification // inferred from electronic annotation /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045609 // positive regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 2000982 // positive regulation of inner ear receptor cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 221337_s_at NM_021780 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021780.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 29 (ADAM29), transcript variant 2, mRNA. /FEA=CDS /GEN=ADAM29 /PROD=a disintegrin and metalloproteinase domain 29,isoform 2 preproprotein /DB_XREF=gi:11497604 /UG=Hs.126838 a disintegrin and metalloproteinase domain 29 /FL=gb:NM_021780.1 gb:AF171931.1 NM_021780 ADAM metallopeptidase domain 29 /// uncharacterized LOC101928551 ADAM29 /// LOC101928551 11086 /// 101928551 NM_001130703 /// NM_001130704 /// NM_001130705 /// NM_001278125 /// NM_001278126 /// NM_001278127 /// NM_014269 /// XM_005262704 /// XM_005262705 /// XR_244763 /// XR_244764 /// XR_249706 /// XR_249707 /// XR_251703 /// XR_251704 /// XR_425814 /// XR_427641 /// XR_431812 0006508 // proteolysis // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation 221338_at NM_024123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024123.1 /DEF=Homo sapiens putative Ly-6 superfamily member (G6E), mRNA. /FEA=CDS /GEN=G6E /PROD=putative Ly-6 superfamily member /DB_XREF=gi:13236491 /UG=Hs.247883 putative Ly-6 superfamily member /FL=gb:NM_024123.1 NM_024123 lymphocyte antigen 6 complex, locus G6E (pseudogene) LY6G6E 79136 NM_001003721 /// NM_024123 /// NR_003673 /// NR_024541 221339_at NM_013941 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013941.1 /DEF=Homo sapiens olfactory receptor, family 10, subfamily C, member 1 (OR10C1), mRNA. /FEA=CDS /GEN=OR10C1 /PROD=olfactory receptor, family 10, subfamily C,member 1 /DB_XREF=gi:7363436 /UG=Hs.247860 olfactory receptor, family 10, subfamily C, member 1 /FL=gb:NM_013941.1 NM_013941 olfactory receptor, family 10, subfamily C, member 1 OR10C1 442194 NM_013941 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221340_at NM_005193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005193.1 /DEF=Homo sapiens caudal type homeo box transcription factor 4 (CDX4), mRNA. /FEA=CDS /GEN=CDX4 /PROD=caudal type homeo box transcription factor 4 /DB_XREF=gi:4885126 /UG=Hs.248098 caudal type homeo box transcription factor 4 /FL=gb:NM_005193.1 NM_005193 caudal type homeobox 4 CDX4 1046 NM_005193 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0060711 // labyrinthine layer development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221341_s_at NM_003552 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003552.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily D, member 4 (OR1D4), mRNA. /FEA=CDS /GEN=OR1D4 /PROD=olfactory receptor, family 1, subfamily D,member 4 /DB_XREF=gi:11415031 /UG=Hs.247835 olfactory receptor, family 1, subfamily D, member 4 /FL=gb:NM_003552.1 NM_003552 olfactory receptor, family 1, subfamily D, member 5 OR1D5 8386 NM_014566 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221342_at NM_025260 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025260.1 /DEF=Homo sapiens G6B protein (G6B), mRNA. /FEA=CDS /GEN=G6B /PROD=G6B protein /DB_XREF=gi:13376871 /UG=Hs.247879 G6B protein /FL=gb:NM_025260.1 NM_025260 chromosome 6 open reading frame 25 C6orf25 80739 NM_025260 /// NM_138272 /// NM_138273 /// NM_138274 /// NM_138275 /// NM_138276 /// NM_138277 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008201 // heparin binding // inferred from electronic annotation 221343_at NM_013937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013937.1 /DEF=Homo sapiens olfactory receptor, family 11, subfamily A, member 1 (OR11A1), mRNA. /FEA=CDS /GEN=OR11A1 /PROD=olfactory receptor, family 11, subfamily A,member 1 /DB_XREF=gi:7363440 /UG=Hs.247861 olfactory receptor, family 11, subfamily A, member 1 /FL=gb:NM_013937.1 NM_013937 olfactory receptor, family 11, subfamily A, member 1 OR11A1 26531 NM_013937 /// XM_005249001 /// XM_005249002 /// XM_005272788 /// XM_005272789 /// XM_005274843 /// XM_005274844 /// XM_005274934 /// XM_005274935 /// XM_005275089 /// XM_005275090 /// XM_005275230 /// XM_005275231 /// XM_005275365 /// XM_005275366 /// XM_005275524 /// XM_005275525 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221344_at NM_013936 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013936.1 /DEF=Homo sapiens olfactory receptor, family 12, subfamily D, member 2 (OR12D2), mRNA. /FEA=CDS /GEN=OR12D2 /PROD=olfactory receptor, family 12, subfamily D,member 2 /DB_XREF=gi:7363442 /UG=Hs.247862 olfactory receptor, family 12, subfamily D, member 2 /FL=gb:NM_013936.1 NM_013936 olfactory receptor, family 12, subfamily D, member 2 OR12D2 26529 NM_013936 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221345_at NM_005306 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005306.1 /DEF=Homo sapiens G protein-coupled receptor 43 (GPR43), mRNA. /FEA=CDS /GEN=GPR43 /PROD=G protein-coupled receptor 43 /DB_XREF=gi:4885332 /UG=Hs.248056 G protein-coupled receptor 43 /FL=gb:NM_005306.1 NM_005306 free fatty acid receptor 2 FFAR2 2867 NM_005306 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 221346_at NM_012351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012351.1 /DEF=Homo sapiens olfactory receptor, family 10, subfamily J, member 1 (OR10J1), mRNA. /FEA=CDS /GEN=OR10J1 /PROD=olfactory receptor, family 10, subfamily J,member 1 /DB_XREF=gi:6912549 /UG=Hs.247937 olfactory receptor, family 10, subfamily J, member 1 /FL=gb:NM_012351.1 NM_012351 olfactory receptor, family 10, subfamily J, member 1 OR10J1 26476 NM_012351 /// XM_006711271 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221347_at NM_012125 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012125.1 /DEF=Homo sapiens cholinergic receptor, muscarinic 5 (CHRM5), mRNA. /FEA=CDS /GEN=CHRM5 /PROD=cholinergic receptor, muscarinic 5 /DB_XREF=gi:7108335 /UG=Hs.247920 cholinergic receptor, muscarinic 5 /FL=gb:AF026263.1 gb:NM_012125.1 NM_012125 cholinergic receptor, muscarinic 5 CHRM5 1133 NM_012125 /// XM_005254141 0001696 // gastric acid secretion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007197 // adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015872 // dopamine transport // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0060304 // regulation of phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016907 // G-protein coupled acetylcholine receptor activity // inferred from electronic annotation 221348_at NM_024409 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024409.1 /DEF=Homo sapiens natriuretic peptide precursor C (NPPC), mRNA. /FEA=CDS /GEN=NPPC /PROD=natriuretic peptide precursor C /DB_XREF=gi:13249345 /UG=Hs.247916 natriuretic peptide precursor C /FL=gb:NM_024409.1 NM_024409 natriuretic peptide C NPPC 4880 NM_024409 0001503 // ossification // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0003418 // growth plate cartilage chondrocyte differentiation // inferred from sequence or structural similarity /// 0003419 // growth plate cartilage chondrocyte proliferation // inferred from sequence or structural similarity /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030823 // regulation of cGMP metabolic process // inferred from direct assay /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0048513 // organ development // inferred from electronic annotation /// 0048660 // regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051053 // negative regulation of DNA metabolic process // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from direct assay /// 1900194 // negative regulation of oocyte maturation // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0051428 // peptide hormone receptor binding // inferred from electronic annotation 221349_at NM_007128 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_007128.1 /DEF=Homo sapiens pre-B lymphocyte gene 1 (VPREB1), mRNA. /FEA=CDS /GEN=VPREB1 /PROD=pre-B lymphocyte gene 1 /DB_XREF=gi:9507238 /UG=Hs.247979 pre-B lymphocyte gene 1 /FL=gb:NM_007128.1 NM_007128 pre-B lymphocyte 1 VPREB1 7441 NM_007128 0006955 // immune response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221350_at NM_022658 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022658.1 /DEF=Homo sapiens homeo box C8 (HOXC8), mRNA. /FEA=CDS /GEN=HOXC8 /PROD=homeo box C8 /DB_XREF=gi:12056968 /UG=Hs.248050 homeo box C8 /FL=gb:NM_022658.1 NM_022658 homeobox C8 HOXC8 3224 NM_022658 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221351_at NM_000524 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000524.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), mRNA. /FEA=CDS /GEN=HTR1A /PROD=5-hydroxytryptamine (serotonin) receptor 1A /DB_XREF=gi:4504530 /UG=Hs.247940 5-hydroxytryptamine (serotonin) receptor 1A /FL=gb:NM_000524.1 NM_000524 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled HTR1A 3350 NM_000524 0001662 // behavioral fear response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007198 // adenylate cyclase-inhibiting serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from sequence or structural similarity /// 0007610 // behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014062 // regulation of serotonin secretion // inferred from sequence or structural similarity /// 0035640 // exploration behavior // inferred from sequence or structural similarity /// 0042053 // regulation of dopamine metabolic process // inferred from sequence or structural similarity /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042428 // serotonin metabolic process // inferred from sequence or structural similarity /// 0046883 // regulation of hormone secretion // inferred from electronic annotation /// 0050795 // regulation of behavior // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0004993 // serotonin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 221352_at NM_013288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013288.1 /DEF=Homo sapiens DNA binding protein for surfactant protein B (HUMBINDC), mRNA. /FEA=CDS /GEN=HUMBINDC /PROD=DNA binding protein for surfactant protein B /DB_XREF=gi:7019420 /UG=Hs.247992 DNA binding protein for surfactant protein B /FL=gb:NM_013288.1 gb:L10405.1 NM_013288 0003677 // DNA binding // inferred from electronic annotation 221353_at NM_002550 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002550.1 /DEF=Homo sapiens olfactory receptor, family 3, subfamily A, member 1 (OR3A1), mRNA. /FEA=CDS /GEN=OR3A1 /PROD=olfactory receptor, family 3, subfamily A,member 1 /DB_XREF=gi:4505518 /UG=Hs.248155 olfactory receptor, family 3, subfamily A, member 1 /FL=gb:NM_002550.1 NM_002550 olfactory receptor, family 3, subfamily A, member 1 OR3A1 4994 NM_002550 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221354_s_at NM_005297 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005297.1 /DEF=Homo sapiens G protein-coupled receptor 24 (GPR24), mRNA. /FEA=CDS /GEN=GPR24 /PROD=G protein-coupled receptor 24 /DB_XREF=gi:4885312 /UG=Hs.248122 G protein-coupled receptor 24 /FL=gb:NM_005297.1 NM_005297 melanin-concentrating hormone receptor 1 MCHR1 2847 NM_005297 /// XM_005261581 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007631 // feeding behavior // traceable author statement /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008188 // neuropeptide receptor activity // traceable author statement /// 0030273 // melanin-concentrating hormone receptor activity // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation 221355_at NM_005199 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005199.3 /DEF=Homo sapiens cholinergic receptor, nicotinic, gamma polypeptide (CHRNG), mRNA. /FEA=CDS /GEN=CHRNG /PROD=cholinergic receptor, nicotinic, gammapolypeptide /DB_XREF=gi:7382453 /UG=Hs.248101 cholinergic receptor, nicotinic, gamma polypeptide /FL=gb:NM_005199.3 NM_005199 cholinergic receptor, nicotinic, gamma (muscle) CHRNG 1146 NM_005199 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005892 // acetylcholine-gated channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004889 // acetylcholine-activated cation-selective channel activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015267 // channel activity // traceable author statement /// 0015464 // acetylcholine receptor activity // traceable author statement 221356_x_at NM_016318 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016318.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), mRNA. /FEA=CDS /GEN=P2RX2 /PROD=P2X2C receptor /DB_XREF=gi:7706628 /UG=Hs.258580 purinergic receptor P2X, ligand-gated ion channel, 2 /FL=gb:AF190824.1 gb:NM_016318.1 NM_016318 purinergic receptor P2X, ligand-gated ion channel, 2 P2RX2 22953 NM_001282164 /// NM_001282165 /// NM_012226 /// NM_016318 /// NM_170682 /// NM_170683 /// NM_174872 /// NM_174873 /// XM_005266154 /// XM_005266155 /// XM_005266156 0001666 // response to hypoxia // inferred from electronic annotation /// 0003029 // detection of hypoxic conditions in blood by carotid body chemoreceptor signaling // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // inferred from direct assay /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045340 // mercury ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation 221357_at NM_000741 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000741.1 /DEF=Homo sapiens cholinergic receptor, muscarinic 4 (CHRM4), mRNA. /FEA=CDS /GEN=CHRM4 /PROD=cholinergic receptor, muscarinic 4 /DB_XREF=gi:4502820 /UG=Hs.248100 cholinergic receptor, muscarinic 4 /FL=gb:NM_000741.1 NM_000741 cholinergic receptor, muscarinic 4 CHRM4 1132 NM_000741 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007197 // adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0040012 // regulation of locomotion // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016907 // G-protein coupled acetylcholine receptor activity // inferred from electronic annotation 221358_at NM_005286 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005286.1 /DEF=Homo sapiens G protein-coupled receptor 8 (GPR8), mRNA. /FEA=CDS /GEN=GPR8 /PROD=G protein-coupled receptor 8 /DB_XREF=gi:4885344 /UG=Hs.248118 G protein-coupled receptor 8 /FL=gb:NM_005286.1 NM_005286 neuropeptides B/W receptor 2 NPBWR2 2832 NM_005286 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0038003 // opioid receptor signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008188 // neuropeptide receptor activity // inferred from electronic annotation 221359_at NM_000514 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000514.1 /DEF=Homo sapiens glial cell derived neurotrophic factor (GDNF), mRNA. /FEA=CDS /GEN=GDNF /PROD=glial cell derived neurotrophic factorprecursor /DB_XREF=gi:4503974 /UG=Hs.248114 glial cell derived neurotrophic factor /FL=gb:NM_000514.1 NM_000514 glial cell derived neurotrophic factor GDNF 2668 NM_000514 /// NM_001190468 /// NM_001190469 /// NM_001278098 /// NM_199231 /// NM_199234 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from direct assay /// 0001759 // organ induction // inferred from electronic annotation /// 0001941 // postsynaptic membrane organization // inferred from electronic annotation /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0008344 // adult locomotory behavior // traceable author statement /// 0021784 // postganglionic parasympathetic nervous system development // inferred from sequence or structural similarity /// 0030432 // peristalsis // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from direct assay /// 0032770 // positive regulation of monooxygenase activity // inferred from direct assay /// 0033603 // positive regulation of dopamine secretion // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0060676 // ureteric bud formation // inferred from electronic annotation /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0072107 // positive regulation of ureteric bud formation // inferred from direct assay /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 221360_s_at NM_004122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004122.1 /DEF=Homo sapiens growth hormone secretagogue receptor (GHSR), mRNA. /FEA=CDS /GEN=GHSR /PROD=growth hormone secretagogue receptor /DB_XREF=gi:4758433 /UG=Hs.248115 growth hormone secretagogue receptor /FL=gb:U60181.1 gb:NM_004122.1 NM_004122 growth hormone secretagogue receptor GHSR 2693 NM_004122 /// NM_198407 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008154 // actin polymerization or depolymerization // inferred from direct assay /// 0008343 // adult feeding behavior // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from direct assay /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0030252 // growth hormone secretion // traceable author statement /// 0032094 // response to food // inferred from electronic annotation /// 0032100 // positive regulation of appetite // inferred from sequence or structural similarity /// 0032691 // negative regulation of interleukin-1 beta production // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042536 // negative regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043134 // regulation of hindgut contraction // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from direct assay /// 0045923 // positive regulation of fatty acid metabolic process // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046697 // decidualization // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0051963 // regulation of synapse assembly // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0001616 // growth hormone secretagogue receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016520 // growth hormone-releasing hormone receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation 221361_at NM_006189 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006189.1 /DEF=Homo sapiens olfactory marker protein (OMP), mRNA. /FEA=CDS /GEN=OMP /PROD=olfactory marker protein /DB_XREF=gi:5453827 /UG=Hs.248153 olfactory marker protein /FL=gb:NM_006189.1 NM_006189 olfactory marker protein OMP 4975 NM_006189 0007165 // signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation 221362_at NM_024012 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_024012.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 5A (HTR5A), mRNA. /FEA=CDS /GEN=HTR5A /PROD=5-hydroxytryptamine (serotonin) receptor 5A /DB_XREF=gi:13236496 /UG=Hs.248137 5-hydroxytryptamine (serotonin) receptor 5A /FL=gb:NM_024012.1 NM_024012 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled HTR5A 3361 NM_024012 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay 221363_x_at NM_005298 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005298.1 /DEF=Homo sapiens G protein-coupled receptor 25 (GPR25), mRNA. /FEA=CDS /GEN=GPR25 /PROD=G protein-coupled receptor 25 /DB_XREF=gi:4885314 /UG=Hs.248123 G protein-coupled receptor 25 /FL=gb:NM_005298.1 NM_005298 G protein-coupled receptor 25 GPR25 2848 NM_005298 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221364_at NM_001510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001510.1 /DEF=Homo sapiens glutamate receptor, ionotropic, delta 2 (GRID2), mRNA. /FEA=CDS /GEN=GRID2 /PROD=glutamate receptor, ionotropic, delta 2 /DB_XREF=gi:4557632 /UG=Hs.248130 glutamate receptor, ionotropic, delta 2 /FL=gb:AF009014.1 gb:NM_001510.1 NM_001510 glutamate receptor, ionotropic, delta 2 GRID2 2895 NM_001286838 /// NM_001510 /// XM_006714195 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007215 // glutamate receptor signaling pathway // traceable author statement /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0021707 // cerebellar granule cell differentiation // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // not recorded /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035235 // ionotropic glutamate receptor signaling pathway // not recorded /// 0035249 // synaptic transmission, glutamatergic // not recorded /// 0035249 // synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008328 // ionotropic glutamate receptor complex // not recorded /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // not recorded /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // not recorded 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activity // not recorded /// 0005215 // transporter activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005234 // extracellular-glutamate-gated ion channel activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008066 // glutamate receptor activity // traceable author statement /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity 221365_at NM_001507 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001507.1 /DEF=Homo sapiens G protein-coupled receptor 38 (GPR38), mRNA. /FEA=CDS /GEN=GPR38 /PROD=G protein-coupled receptor 38 /DB_XREF=gi:4504094 /UG=Hs.248126 G protein-coupled receptor 38 /FL=gb:NM_001507.1 NM_001507 motilin receptor MLNR 2862 NM_001507 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007586 // digestion // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0016520 // growth hormone-releasing hormone receptor activity // inferred from electronic annotation 221366_at NM_006168 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006168.1 /DEF=Homo sapiens NK homeobox (Drosophila), family 6, A (NKX6A), mRNA. /FEA=CDS /GEN=NKX6A /PROD=NK homeobox (Drosophila), family 6, A /DB_XREF=gi:5453787 /UG=Hs.248151 NK homeobox (Drosophila), family 6, A /FL=gb:NM_006168.1 NM_006168 NK6 homeobox 1 NKX6-1 4825 NM_006168 /// XM_006714230 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0021912 // regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification // inferred from electronic annotation /// 0021913 // regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031016 // pancreas development // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045686 // negative regulation of glial cell differentiation // inferred from electronic annotation /// 0045687 // positive regulation of glial cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051594 // detection of glucose // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0072560 // type B pancreatic cell maturation // inferred from sequence or structural similarity /// 2000078 // positive regulation of type B pancreatic cell development // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221367_at NM_005372 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005372.1 /DEF=Homo sapiens v-mos Moloney murine sarcoma viral oncogene homolog (MOS), mRNA. /FEA=CDS /GEN=MOS /PROD=v-mos Moloney murine sarcoma viral oncogenehomolog /DB_XREF=gi:4885488 /UG=Hs.248146 v-mos Moloney murine sarcoma viral oncogene homolog /FL=gb:NM_005372.1 NM_005372 v-mos Moloney murine sarcoma viral oncogene homolog MOS 4342 NM_005372 0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0000186 // activation of MAPKK activity // inferred from sequence or structural similarity /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000212 // meiotic spindle organization // inferred from sequence or structural similarity /// 0006325 // chromatin organization // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0051296 // establishment of meiotic spindle orientation // inferred from sequence or structural similarity /// 1902103 // negative regulation of metaphase/anaphase transition of meiotic cell cycle // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221368_at NM_005383 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005383.1 /DEF=Homo sapiens sialidase 2 (cytosolic sialidase) (NEU2), mRNA. /FEA=CDS /GEN=NEU2 /PROD=sialidase 2 (cytosolic sialidase) /DB_XREF=gi:4885514 /UG=Hs.248148 sialidase 2 (cytosolic sialidase) /FL=gb:NM_005383.1 NM_005383 sialidase 2 (cytosolic sialidase) NEU2 4759 NM_005383 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // traceable author statement /// 0004308 // exo-alpha-sialidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0052794 // exo-alpha-(2->3)-sialidase activity // inferred from direct assay /// 0052795 // exo-alpha-(2->6)-sialidase activity // inferred from electronic annotation /// 0052796 // exo-alpha-(2->8)-sialidase activity // inferred from electronic annotation 221369_at NM_005958 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005958.1 /DEF=Homo sapiens melatonin receptor 1A (MTNR1A), mRNA. /FEA=CDS /GEN=MTNR1A /PROD=melatonin receptor 1A /DB_XREF=gi:5174592 /UG=Hs.248147 melatonin receptor 1A /FL=gb:NM_005958.1 gb:U14108.1 NM_005958 melatonin receptor 1A MTNR1A 4543 NM_005958 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007617 // mating behavior // traceable author statement /// 0007623 // circadian rhythm // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008502 // melatonin receptor activity // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction /// 0097159 // organic cyclic compound binding // inferred from physical interaction 221370_at NM_012480 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012480.1 /DEF=Homo sapiens zinc finger protein 73 (Cos12) (ZNF73), mRNA. /FEA=CDS /GEN=ZNF73 /PROD=zinc finger protein 73 (Cos12) /DB_XREF=gi:6912747 /UG=Hs.248167 zinc finger protein 186 (Kruppel type) /FL=gb:NM_012480.1 NM_012480 zinc finger protein 717 ZNF717 100131827 NM_001128223 /// NM_001290208 /// NM_001290209 /// NM_001290210 /// XM_005264710 /// XM_005264711 /// XM_005264712 /// XM_005264713 /// XM_006712910 /// XM_006712911 /// XM_006712912 /// XM_006712913 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 221371_at NM_005092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005092.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), mRNA. /FEA=CDS /GEN=TNFSF18 /PROD=tumor necrosis factor (ligand) superfamily,member 18 /DB_XREF=gi:4827033 /UG=Hs.248197 tumor necrosis factor (ligand) superfamily, member 18 /FL=gb:AF117713.1 gb:AF125303.1 gb:NM_005092.1 NM_005092 tumor necrosis factor (ligand) superfamily, member 18 TNFSF18 8995 NM_005092 0002309 // T cell proliferation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0042129 // regulation of T cell proliferation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from sequence or structural similarity 221372_s_at NM_012226 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012226.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), mRNA. /FEA=CDS /GEN=P2RX2 /PROD=purinergic receptor P2X, ligand-gated ionchannel, 2 /DB_XREF=gi:6912565 /UG=Hs.258580 purinergic receptor P2X, ligand-gated ion channel, 2 /FL=gb:AF109388.1 gb:AF190823.1 gb:NM_012226.1 gb:AF260427.1 NM_012226 purinergic receptor P2X, ligand-gated ion channel, 2 P2RX2 22953 NM_001282164 /// NM_001282165 /// NM_012226 /// NM_016318 /// NM_170682 /// NM_170683 /// NM_174872 /// NM_174873 /// XM_005266154 /// XM_005266155 /// XM_005266156 0001666 // response to hypoxia // inferred from electronic annotation /// 0003029 // detection of hypoxic conditions in blood by carotid body chemoreceptor signaling // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006812 // cation transport // inferred from electronic annotation /// 0006812 // cation transport // non-traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // non-traceable author statement /// 0014832 // urinary bladder smooth muscle contraction // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0035590 // purinergic nucleotide receptor signaling pathway // non-traceable author statement /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // non-traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from physical interaction /// 0051291 // protein heterooligomerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // non-traceable author statement /// 0004931 // extracellular ATP-gated cation channel activity // inferred from direct assay /// 0004931 // extracellular ATP-gated cation channel activity // non-traceable author statement /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015276 // ligand-gated ion channel activity // traceable author statement /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045340 // mercury ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation 221373_x_at NM_004158 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004158.1 /DEF=Homo sapiens persephin (PSPN), mRNA. /FEA=CDS /GEN=PSPN /PROD=persephin /DB_XREF=gi:4758973 /UG=Hs.248159 persephin /FL=gb:AF040962.1 gb:NM_004158.1 NM_004158 persephin PSPN 5623 NM_004158 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 221374_at NM_003868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003868.1 /DEF=Homo sapiens fibroblast growth factor 16 (FGF16), mRNA. /FEA=CDS /GEN=FGF16 /PROD=fibroblast growth factor 16 /DB_XREF=gi:4503690 /UG=Hs.248193 fibroblast growth factor 16 /FL=gb:AB009391.1 gb:NM_003868.1 NM_003868 fibroblast growth factor 16 FGF16 8823 NM_003868 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009266 // response to temperature stimulus // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221375_at NM_003555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003555.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily G, member 1 (OR1G1), mRNA. /FEA=CDS /GEN=OR1G1 /PROD=olfactory receptor, family 1, subfamily G,member 1 /DB_XREF=gi:11415033 /UG=Hs.248183 olfactory receptor, family 1, subfamily G, member 1 /FL=gb:NM_003555.1 NM_003555 olfactory receptor, family 1, subfamily G, member 1 OR1G1 8390 NM_003555 /// XM_006721587 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221376_at NM_003867 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003867.1 /DEF=Homo sapiens fibroblast growth factor 17 (FGF17), mRNA. /FEA=CDS /GEN=FGF17 /PROD=fibroblast growth factor 17 /DB_XREF=gi:4503692 /UG=Hs.248192 fibroblast growth factor 17 /FL=gb:AB009249.1 gb:NM_003867.1 NM_003867 fibroblast growth factor 17 FGF17 8822 NM_003867 /// XM_005273675 /// XM_005273676 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005105 // type 1 fibroblast growth factor receptor binding // inferred from direct assay /// 0005111 // type 2 fibroblast growth factor receptor binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation 221377_s_at NM_014276 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014276.1 /DEF=Homo sapiens recombining binding protein suppressor of hairless-like (Drosophila) (RBPSUHL), mRNA. /FEA=CDS /GEN=RBPSUHL /PROD=recombining binding protein suppressor ofhairless-like (Drosophila) /DB_XREF=gi:10092591 /UG=Hs.248217 recombining binding protein suppressor of hairless-like (Drosophila) /FL=gb:NM_014276.1 gb:AB026048.1 gb:AB027710.1 gb:AB024964.1 NM_014276 recombination signal binding protein for immunoglobulin kappa J region-like RBPJL 11317 NM_001281448 /// NM_001281449 /// NM_014276 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 221378_at NM_005454 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005454.1 /DEF=Homo sapiens cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily) (CER1), mRNA. /FEA=CDS /GEN=CER1 /PROD=cerberus 1 /DB_XREF=gi:4885134 /UG=Hs.248204 cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily) /FL=gb:NM_005454.1 NM_005454 cerberus 1, DAN family BMP antagonist CER1 9350 NM_005454 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0003419 // growth plate cartilage chondrocyte proliferation // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0009948 // anterior/posterior axis specification // inferred from sequence or structural similarity /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0023019 // signal transduction involved in regulation of gene expression // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // inferred from sequence or structural similarity /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from sequence or structural similarity /// 0035582 // sequestering of BMP in extracellular matrix // inferred from direct assay /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0042074 // cell migration involved in gastrulation // inferred from sequence or structural similarity /// 0048263 // determination of dorsal identity // inferred from mutant phenotype /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 2000381 // negative regulation of mesoderm development // inferred from mutant phenotype /// 2000381 // negative regulation of mesoderm development // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from sequence or structural similarity 0005125 // cytokine activity // inferred from electronic annotation /// 0016015 // morphogen activity // inferred from direct assay /// 0036122 // BMP binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 221379_at NM_020527 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020527.1 /DEF=Homo sapiens HUG1 gene (HUG1), mRNA. /FEA=CDS /GEN=HUG1 /PROD=HUG1 gene /DB_XREF=gi:10092603 /UG=Hs.248216 HUG1 gene /FL=gb:NM_020527.1 NM_020527 221380_at NM_006543 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006543.1 /DEF=Homo sapiens Mahlavu hepatocellular carcinoma (HHCM), mRNA. /FEA=CDS /GEN=HHCM /PROD=Mahlavu hepatocellular carcinoma /DB_XREF=gi:5729868 /UG=Hs.248210 Mahlavu hepatocellular carcinoma /FL=gb:NM_006543.1 NM_006543 221381_s_at NM_006792 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006792.2 /DEF=Homo sapiens mortality factor 4 (MORF4), mRNA. /FEA=CDS /GEN=MORF4 /PROD=mortality factor 4 /DB_XREF=gi:6996927 /UG=Hs.251396 mortality factor 4 /FL=gb:NM_006792.2 NM_006792 mortality factor 4 like 1 MORF4L1 10933 NM_001265603 /// NM_001265604 /// NM_001265605 /// NM_006791 /// NM_206839 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 221382_at NM_012348 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012348.1 /DEF=Homo sapiens olfactory receptor 89 (OLFR89), mRNA. /FEA=CDS /GEN=OLFR89 /PROD=olfactory receptor 89 /DB_XREF=gi:6912547 /UG=Hs.248225 olfactory receptor 89 /FL=gb:NM_012348.1 NM_012348 olfactory receptor, family 2, subfamily N, member 1 pseudogene /// OR2N1P /// OR2N1P 221383_at NM_006056 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006056.1 /DEF=Homo sapiens G protein-coupled receptor 66 (GPR66), mRNA. /FEA=CDS /GEN=GPR66 /PROD=G protein-coupled receptor 66 /DB_XREF=gi:5174442 /UG=Hs.251384 G protein-coupled receptor 66 /FL=gb:AF272362.1 gb:NM_006056.1 NM_006056 neuromedin U receptor 1 NMUR1 10316 NM_006056 /// XM_006712195 /// XM_006712196 0006816 // calcium ion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0006939 // smooth muscle contraction // inferred from expression pattern /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0001607 // neuromedin U receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0008188 // neuropeptide receptor activity // traceable author statement 221384_at NM_021833 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021833.2 /DEF=Homo sapiens uncoupling protein 1 (mitochondrial, proton carrier) (UCP1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=CDS /GEN=UCP1 /PROD=uncoupling protein 1 /DB_XREF=gi:13259539 /UG=Hs.249211 uncoupling protein 1 (mitochondrial, proton carrier) /FL=gb:U28480.1 gb:NM_021833.2 NM_021833 uncoupling protein 1 (mitochondrial, proton carrier) UCP1 7350 NM_021833 /// XM_005263206 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0017077 // oxidative phosphorylation uncoupler activity // inferred from electronic annotation 221385_s_at NM_005305 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005305.1 /DEF=Homo sapiens G protein-coupled receptor 42 (GPR42), mRNA. /FEA=CDS /GEN=GPR42 /PROD=G protein-coupled receptor 42 /DB_XREF=gi:4885330 /UG=Hs.272485 G protein-coupled receptor 42 /FL=gb:NM_005305.1 NM_005305 free fatty acid receptor 3 /// G protein-coupled receptor 42 (gene/pseudogene) FFAR3 /// GPR42 2865 /// 2866 NM_005304 /// NM_005305 0002385 // mucosal immune response // inferred from sequence or structural similarity /// 0002720 // positive regulation of cytokine production involved in immune response // inferred from sequence or structural similarity /// 0002879 // positive regulation of acute inflammatory response to non-antigenic stimulus // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0014061 // regulation of norepinephrine secretion // inferred from sequence or structural similarity /// 0032722 // positive regulation of chemokine production // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from sequence or structural similarity /// 0046885 // regulation of hormone biosynthetic process // inferred from sequence or structural similarity /// 0071398 // cellular response to fatty acid // inferred from direct assay /// 0090276 // regulation of peptide hormone secretion // inferred from sequence or structural similarity /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 221386_at NM_002551 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002551.1 /DEF=Homo sapiens olfactory receptor, family 3, subfamily A, member 2 (OR3A2), mRNA. /FEA=CDS /GEN=OR3A2 /PROD=olfactory receptor, family 3, subfamily A,member 2 /DB_XREF=gi:11321568 /UG=Hs.272377 olfactory receptor, family 3, subfamily A, member 2 /FL=gb:NM_002551.1 NM_002551 olfactory receptor, family 3, subfamily A, member 2 OR3A2 4995 NM_002551 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // traceable author statement /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221387_at NM_022146 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022146.1 /DEF=Homo sapiens neuropeptide FF 1; RFamide-related peptide receptor (OT7T022), mRNA. /FEA=CDS /GEN=OT7T022 /PROD=neuropeptide FF 1; RFamide-related peptidereceptor /DB_XREF=gi:11545886 /UG=Hs.302026 neuropeptide FF 1; RFamide-related peptide receptor /FL=gb:AB040104.1 gb:NM_022146.1 gb:AF268898.1 NM_022146 neuropeptide FF receptor 1 NPFFR1 64106 NM_022146 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0008188 // neuropeptide receptor activity // non-traceable author statement 221388_at NM_014565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014565.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily A, member 1 (OR1A1), mRNA. /FEA=CDS /GEN=OR1A1 /PROD=olfactory receptor, family 1, subfamily A,member 1 /DB_XREF=gi:7657420 /UG=Hs.272376 olfactory receptor, family 1, subfamily A, member 1 /FL=gb:NM_014565.1 NM_014565 olfactory receptor, family 1, subfamily A, member 1 OR1A1 8383 NM_014565 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221389_at NM_014589 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014589.1 /DEF=Homo sapiens phospholipase A2, group IIE (PLA2G2E), mRNA. /FEA=CDS /GEN=PLA2G2E /PROD=phospholipase A2, group IIE /DB_XREF=gi:7657460 /UG=Hs.272372 phospholipase A2, group IIE /FL=gb:AF189279.1 gb:NM_014589.1 NM_014589 phospholipase A2, group IIE PLA2G2E 30814 NM_014589 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // traceable author statement 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221390_s_at NM_004686 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004686.1 /DEF=Homo sapiens myotubularin related protein 7 (MTMR7), mRNA. /FEA=CDS /GEN=MTMR7 /PROD=myotubularin related protein 7 /DB_XREF=gi:10863890 /UG=Hs.26952 myotubularin related protein 7 /FL=gb:NM_004686.1 NM_004686 ankyrin repeat and SOCS box containing 12 /// myotubularin related protein 8 ASB12 /// MTMR8 55613 /// 142689 NM_017677 /// NM_130388 0016311 // dephosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 221391_at NM_023922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023922.1 /DEF=Homo sapiens taste receptor, family B, member 1 (TRB1), mRNA. /FEA=CDS /GEN=TRB1 /PROD=taste receptor, family B, member 1 /DB_XREF=gi:12965181 /UG=Hs.272394 taste receptor, type 2, member 14 /FL=gb:NM_023922.1 NM_023922 taste receptor, type 2, member 14 TAS2R14 50840 NM_023922 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred by curator /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // inferred from direct assay /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221392_at NM_016944 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016944.1 /DEF=Homo sapiens taste receptor, type 2, member 4 (TAS2R4), mRNA. /FEA=CDS /GEN=TAS2R4 /PROD=taste receptor T2R4 /DB_XREF=gi:8394401 /UG=Hs.272387 taste receptor, type 2, member 4 /FL=gb:NM_016944.1 NM_016944 taste receptor, type 2, member 4 TAS2R4 50832 NM_016944 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // traceable author statement /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221393_at NM_014627 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014627.1 /DEF=Homo sapiens G protein-coupled receptor 57 (GPR57), mRNA. /FEA=CDS /GEN=GPR57 /PROD=G protein-coupled receptor 57 /DB_XREF=gi:7657139 /UG=Hs.272383 G protein-coupled receptor 57 /FL=gb:NM_014627.1 NM_014627 trace amine associated receptor 3 (gene/pseudogene) TAAR3 9288 NR_028511 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007606 // sensory perception of chemical stimulus // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001594 // trace-amine receptor activity // inferred from sequence or structural similarity /// 0004930 // G-protein coupled receptor activity // traceable author statement 221394_at NM_014626 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014626.1 /DEF=Homo sapiens G protein-coupled receptor 58 (GPR58), mRNA. /FEA=CDS /GEN=GPR58 /PROD=G protein-coupled receptor 58 /DB_XREF=gi:7657141 /UG=Hs.272382 G protein-coupled receptor 58 /FL=gb:NM_014626.1 NM_014626 trace amine associated receptor 2 TAAR2 9287 NM_001033080 /// NM_014626 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001594 // trace-amine receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement 221395_at NM_023920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023920.1 /DEF=Homo sapiens taste receptor, family B, member 3 (TRB3), mRNA. /FEA=CDS /GEN=TRB3 /PROD=taste receptor, family B, member 3 /DB_XREF=gi:12965177 /UG=Hs.272393 taste receptor, type 2, member 13 /FL=gb:NM_023920.1 NM_023920 taste receptor, type 2, member 13 TAS2R13 50838 NM_023920 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221396_at NM_023919 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023919.1 /DEF=Homo sapiens taste receptor, family B, member 4 (TRB4), mRNA. /FEA=CDS /GEN=TRB4 /PROD=taste receptor, family B, member 4 /DB_XREF=gi:12965175 /UG=Hs.272389 taste receptor, type 2, member 7 /FL=gb:NM_023919.1 NM_023919 taste receptor, type 2, member 7 TAS2R7 50837 NM_023919 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221397_at NM_023921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023921.1 /DEF=Homo sapiens taste receptor, family B, member 2 (TRB2), mRNA. /FEA=CDS /GEN=TRB2 /PROD=taste receptor, family B, member 2 /DB_XREF=gi:12965179 /UG=Hs.272392 taste receptor, type 2, member 10 /FL=gb:NM_023921.1 NM_023921 taste receptor, type 2, member 10 TAS2R10 50839 NM_023921 /// XM_006719082 /// XM_006725535 /// XM_006726236 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221398_at NM_023918 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023918.1 /DEF=Homo sapiens taste receptor, family B, member 5 (TRB5), mRNA. /FEA=CDS /GEN=TRB5 /PROD=taste receptor, family B, member 5 /DB_XREF=gi:12965173 /UG=Hs.272390 taste receptor, type 2, member 8 /FL=gb:NM_023918.1 NM_023918 taste receptor, type 2, member 8 TAS2R8 50836 NM_023918 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221399_at NM_021783 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021783.1 /DEF=Homo sapiens XEDAR (XEDAR), mRNA. /FEA=CDS /GEN=XEDAR /PROD=X-linked ectodysplasin receptor /DB_XREF=gi:11140822 /UG=Hs.302017 XEDAR /FL=gb:AF298812.1 gb:NM_021783.1 NM_021783 ectodysplasin A2 receptor EDA2R 60401 NM_001199687 /// NM_001199688 /// NM_001199689 /// NM_001242310 /// NM_021783 /// XM_005262285 /// XM_006724675 /// XM_006724676 /// XM_006724677 /// XM_006724678 /// XM_006724679 /// XR_244499 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008544 // epidermis development // non-traceable author statement /// 0009790 // embryo development // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // non-traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004872 // receptor activity // inferred from direct assay /// 0005031 // tumor necrosis factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221400_at NM_017433 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017433.1 /DEF=Homo sapiens myosin IIIA (MYO3A), mRNA. /FEA=CDS /GEN=MYO3A /PROD=myosin IIIA /DB_XREF=gi:8393809 /UG=Hs.279907 myosin IIIA /FL=gb:AF229172.1 gb:NM_017433.1 NM_017433 myosin IIIA MYO3A 53904 NM_017433 0006200 // ATP catabolic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay /// 0032426 // stereocilium bundle tip // inferred from electronic annotation /// 0032433 // filopodium tip // inferred from electronic annotation 0000146 // microfilament motor activity // inferred from direct assay /// 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030898 // actin-dependent ATPase activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0060002 // plus-end directed microfilament motor activity // inferred from direct assay 221401_at NM_014404 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014404.1 /DEF=Homo sapiens calcium channel, voltage-dependent, gamma subunit 5 (CACNG5), mRNA. /FEA=CDS /GEN=CACNG5 /PROD=calcium channel, voltage-dependent, gammasubunit 5 /DB_XREF=gi:7656949 /UG=Hs.278907 calcium channel, voltage-dependent, gamma subunit 5 /FL=gb:NM_014404.1 NM_014404 calcium channel, voltage-dependent, gamma subunit 5 CACNG5 27091 NM_014404 /// NM_145811 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // traceable author statement 221402_at NM_012360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012360.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily F, member 8 (OR1F8), mRNA. /FEA=CDS /GEN=OR1F8 /PROD=olfactory receptor, family 1, subfamily F,member 8 /DB_XREF=gi:6912553 /UG=Hs.278464 olfactory receptor, family 1, subfamily F, member 1 /FL=gb:NM_012360.1 NM_012360 olfactory receptor, family 1, subfamily F, member 1 OR1F1 4992 NM_012360 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221403_s_at NM_016421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016421.1 /DEF=Homo sapiens relaxininsulin-like factor 1 (LOC51746), mRNA. /FEA=CDS /GEN=LOC51746 /PROD=relaxininsulin-like factor 1 /DB_XREF=gi:7706532 /UG=Hs.279000 relaxininsulin-like factor 1 /FL=gb:AF135824.1 gb:NM_016421.1 NM_016421 insulin-like 6 INSL6 11172 NM_007179 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005179 // hormone activity // non-traceable author statement 221404_at NM_014440 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014440.1 /DEF=Homo sapiens Interleukin-1 Superfamily 1 (FIL1(EPSILON)), mRNA. /FEA=CDS /GEN=FIL1(EPSILON) /PROD=Interleukin-1 Superfamily 1 /DB_XREF=gi:7657091 /UG=Hs.278910 Interleukin-1 Superfamily 1 /FL=gb:AF201831.1 gb:NM_014440.1 NM_014440 interleukin 36, alpha IL36A 27179 NM_014440 /// XM_005263639 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // non-traceable author statement 221405_at NM_016317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016317.1 /DEF=Homo sapiens neutral sphingomyelinase (LOC51190), mRNA. /FEA=CDS /GEN=LOC51190 /PROD=neutral sphingomyelinase /DB_XREF=gi:7705928 /UG=Hs.278964 neutral sphingomyelinase /FL=gb:AF069740.1 gb:NM_016317.1 NM_016317 221406_s_at NM_025259 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_025259.1 /DEF=Homo sapiens NG23 protein (NG23), mRNA. /FEA=CDS /GEN=NG23 /PROD=NG23 protein /DB_XREF=gi:13376869 /UG=Hs.296598 NG23 protein /FL=gb:NM_025259.1 NM_025259 MSH5-SAPCD1 readthrough (NMD candidate) /// suppressor APC domain containing 1 MSH5-SAPCD1 /// SAPCD1 401251 /// 100532732 NM_001039651 /// NR_037846 0000710 // meiotic mismatch repair // /// 0006200 // ATP catabolic process // /// 0006298 // mismatch repair // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007131 // reciprocal meiotic recombination // /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007136 // meiotic prophase II // traceable author statement /// 0045143 // homologous chromosome segregation // /// 0051026 // chiasma assembly // 0000795 // synaptonemal complex // /// 0032300 // mismatch repair complex // 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // 221407_at NM_020660 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020660.1 /DEF=Homo sapiens connexin-36 (CX36), mRNA. /FEA=CDS /GEN=CX36 /PROD=connexin-36 /DB_XREF=gi:10190697 /UG=Hs.283816 connexin-36 /FL=gb:NM_020660.1 NM_020660 gap junction protein, delta 2, 36kDa GJD2 57369 NM_020660 0001508 // action potential // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005921 // gap junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005243 // gap junction channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221408_x_at NM_018932 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018932.1 /DEF=Homo sapiens protocadherin beta 12 (PCDHB12), mRNA. /FEA=CDS /GEN=PCDHB12 /PROD=protocadherin beta 12 /DB_XREF=gi:9256605 /UG=Hs.283083 protocadherin beta 12 /FL=gb:AF152491.1 gb:NM_018932.1 NM_018932 protocadherin beta 12 PCDHB12 56124 NM_018932 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 221409_at NM_019897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019897.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily S, member 2 (OR2S2), mRNA. /FEA=CDS /GEN=OR2S2 /PROD=olfactory receptor, family 2, subfamily S,member 2 /DB_XREF=gi:10092668 /UG=Hs.283806 olfactory receptor, family 2, subfamily S, member 2 /FL=gb:NM_019897.1 NM_019897 olfactory receptor, family 2, subfamily S, member 2 OR2S2 56656 NM_019897 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement 221410_x_at NM_018937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018937.1 /DEF=Homo sapiens protocadherin beta 3 (PCDHB3), mRNA. /FEA=CDS /GEN=PCDHB3 /PROD=protocadherin beta 3 /DB_XREF=gi:9256613 /UG=Hs.283086 protocadherin beta 3 /FL=gb:AF152496.1 gb:NM_018937.1 NM_018937 protocadherin beta 3 PCDHB3 56132 NM_018937 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 221411_at NM_021193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021193.1 /DEF=Homo sapiens homeo box D12 (HOXD12), mRNA. /FEA=CDS /GEN=HOXD12 /PROD=homeo box D12 /DB_XREF=gi:10864002 /UG=Hs.283958 homeo box D12 /FL=gb:NM_021193.1 NM_021193 homeobox D12 HOXD12 3238 NM_021193 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation 0000228 // nuclear chromosome // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221412_at NM_020633 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_020633.1 /DEF=Homo sapiens V1R-like 1 (V1RL1), mRNA. /FEA=CDS /GEN=V1RL1 /PROD=V1R-like 1 /DB_XREF=gi:10190667 /UG=Hs.287372 V1R-like 1 /FL=gb:NM_020633.1 gb:AF302903.1 gb:AF255342.1 NM_020633 vomeronasal 1 receptor 1 VN1R1 57191 NM_020633 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0019236 // response to pheromone // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016503 // pheromone receptor activity // inferred from electronic annotation 221413_at NM_004732 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_004732.1 /DEF=Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 3 (KCNAB3), mRNA. /FEA=CDS /GEN=KCNAB3 /PROD=potassium voltage-gated channel, shaker-relatedsubfamily, beta member 3 /DB_XREF=gi:4758619 /UG=Hs.284220 potassium voltage-gated channel, shaker-related subfamily, beta member 3 /FL=gb:AF016411.1 gb:NM_004732.1 NM_004732 potassium voltage-gated channel, shaker-related subfamily, beta member 3 KCNAB3 9196 NM_004732 /// XM_005256849 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 221414_s_at NM_030931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030931.1 /DEF=Homo sapiens epididymal secretory protein ESP13.2 (ESP13.2), mRNA. /FEA=CDS /GEN=ESP13.2 /PROD=epididymal secretory protein ESP13.2 /DB_XREF=gi:13624332 /FL=gb:NM_030931.1 NM_030931 defensin, beta 126 DEFB126 81623 NM_030931 0006952 // defense response // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0030112 // glycocalyx // inferred from electronic annotation 221415_s_at NM_030772 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030772.1 /DEF=Homo sapiens connexin 59 (GJA10), mRNA. /FEA=CDS /GEN=GJA10 /PROD=connexin 59 /DB_XREF=gi:13540536 /FL=gb:NM_030772.1 NM_030772 gap junction protein, alpha 9, 59kDa /// GJA9-MYCBP readthrough /// MYC binding protein GJA9 /// GJA9-MYCBP /// MYCBP 26292 /// 81025 /// 100527950 NM_012333 /// NM_030772 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 221416_at NM_022819 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_022819.1 /DEF=Homo sapiens phospholipase A2, group IIF (PLA2G2F), mRNA. /FEA=CDS /GEN=PLA2G2F /PROD=phospholipase A2, group IIF /DB_XREF=gi:12383057 /UG=Hs.302034 phospholipase A2, group IIF /FL=gb:AF306566.1 gb:NM_022819.1 NM_022819 phospholipase A2, group IIF PLA2G2F 64600 NM_022819 /// XM_006710817 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement 0004623 // phospholipase A2 activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221417_x_at NM_030760 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030760.1 /DEF=Homo sapiens endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 (EDG8), mRNA. /FEA=CDS /GEN=EDG8 /PROD=endothelial differentiation, sphingolipidG-protein-coupled receptor, 8 /DB_XREF=gi:13540516 /FL=gb:NM_030760.1 NM_030760 sphingosine-1-phosphate receptor 5 S1PR5 53637 NM_001166215 /// NM_030760 /// XM_005259937 0003376 // sphingosine-1-phosphate signaling pathway // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0038036 // sphingosine-1-phosphate receptor activity // inferred from electronic annotation 221418_s_at NM_005481 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005481.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein, 95-kD subunit (TRAP95), mRNA. /FEA=CDS /GEN=TRAP95 /PROD=thyroid hormone receptor-associated protein,95-kD subunit /DB_XREF=gi:4885646 /UG=Hs.31659 thyroid hormone receptor-associated protein, 95-kD subunit /FL=gb:AF121228.1 gb:NM_005481.1 NM_005481 mediator complex subunit 16 MED16 10025 NM_005481 /// XM_006722600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from direct assay /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 221419_s_at NM_013307 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_013307.1 /DEF=Homo sapiens non-functional folate binding protein (HSAF000381), mRNA. /FEA=CDS /GEN=HSAF000381 /PROD=non-functional folate binding protein /DB_XREF=gi:7019412 /FL=gb:NM_013307.1 NM_013307 221420_at NM_005179 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005179.1 /DEF=Homo sapiens avian lymphoma virus-derived transforming sequence (BLYM), mRNA. /FEA=CDS /GEN=BLYM /PROD=avian lymphoma virus-derived transformingsequence /DB_XREF=gi:4885092 /UG=Hs.329703 avian lymphoma virus-derived transforming sequence /FL=gb:NM_005179.1 NM_005179 221421_s_at NM_030955 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030955.1 /DEF=Homo sapiens a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12 (ADAMTS12), mRNA. /FEA=CDS /GEN=ADAMTS12 /PROD=a disintegrin-like and metalloprotease(reprolysin type) with thrombospondin type 1 motif, 12 /DB_XREF=gi:13569927 /FL=gb:NM_030955.1 NM_030955 ADAM metallopeptidase with thrombospondin type 1 motif, 12 ADAMTS12 81792 NM_030955 0006508 // proteolysis // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0030167 // proteoglycan catabolic process // inferred from direct assay /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 1901509 // regulation of endothelial tube morphogenesis // inferred from direct assay /// 1902203 // negative regulation of hepatocyte growth factor receptor signaling pathway // inferred from direct assay /// 1902548 // negative regulation of cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 2001113 // negative regulation of cellular response to hepatocyte growth factor stimulus // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221422_s_at NM_030814 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030814.1 /DEF=Homo sapiens hypothetical protein GL012 (GL012), mRNA. /FEA=CDS /GEN=GL012 /PROD=hypothetical protein GL012 /DB_XREF=gi:13540607 /FL=gb:NM_030814.1 NM_030814 microRNA 600 /// MIR600 host gene (non-protein coding) MIR600 /// MIR600HG 81571 /// 693185 NM_030814 /// NR_026677 /// NR_030331 221423_s_at NM_030799 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030799.1 /DEF=Homo sapiens hypothetical protein AF140225 (AF140225), mRNA. /FEA=CDS /GEN=AF140225 /PROD=hypothetical protein AF140225 /DB_XREF=gi:13540583 /FL=gb:NM_030799.1 NM_030799 Yip1 domain family, member 5 YIPF5 81555 NM_001024947 /// NM_001271732 /// NM_030799 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030134 // ER to Golgi transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from electronic annotation 221424_s_at NM_030774 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030774.1 /DEF=Homo sapiens prostate specific G-protein coupled receptor (PSGR), mRNA. /FEA=CDS /GEN=PSGR /PROD=prostate specific G-protein coupled receptor /DB_XREF=gi:13540538 /FL=gb:NM_030774.1 NM_030774 olfactory receptor, family 51, subfamily E, member 2 OR51E2 81285 NM_030774 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from sequence or structural similarity /// 1900135 // positive regulation of renin secretion into blood stream // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003707 // steroid hormone receptor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation /// 0038023 // signaling receptor activity // inferred from sequence or structural similarity 221425_s_at NM_030940 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030940.1 /DEF=Homo sapiens hypothetical protein MGC4276 similar to CG8198 (MGC4276), mRNA. /FEA=CDS /GEN=MGC4276 /PROD=hypothetical protein MGC4276 similar to CG8198 /DB_XREF=gi:13569910 /FL=gb:NM_030940.1 NM_030940 iron-sulfur cluster assembly 1 ISCA1 81689 NM_030940 0016226 // iron-sulfur cluster assembly // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 221426_s_at NM_012373 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012373.1 /DEF=Homo sapiens olfactory receptor, family 3, subfamily A, member 3 (OR3A3), mRNA. /FEA=CDS /GEN=OR3A3 /PROD=olfactory receptor, family 3, subfamily A,member 7 /DB_XREF=gi:13562103 /FL=gb:NM_012373.1 NM_012373 olfactory receptor, family 3, subfamily A, member 3 OR3A3 8392 NM_012373 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221427_s_at NM_030937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030937.1 /DEF=Homo sapiens hypothetical protein hCLA-iso (HCLA-ISO), mRNA. /FEA=CDS /GEN=HCLA-ISO /PROD=hypothetical protein hCLA-iso /DB_XREF=gi:13569904 /FL=gb:NM_030937.1 NM_030937 cyclin L2 CCNL2 81669 NM_001039577 /// NM_001144867 /// NM_001144868 /// NM_030937 /// XM_005244803 /// XM_006710931 /// XM_006710932 /// XM_006710933 /// XM_006710934 /// XR_241043 /// XR_426629 /// XR_426630 /// XR_426631 /// XR_426632 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 221428_s_at NM_030921 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030921.1 /DEF=Homo sapiens hypothetical protein DC42 (DC42), mRNA. /FEA=CDS /GEN=DC42 /PROD=hypothetical protein DC42 /DB_XREF=gi:13569880 /FL=gb:NM_030921.1 NM_030921 transducin (beta)-like 1 X-linked receptor 1 TBL1XR1 79718 NM_024665 /// XM_005247771 /// XM_005247772 /// XM_005247775 /// XM_005247776 /// XM_006713745 /// XM_006713746 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0047485 // protein N-terminus binding // inferred from physical interaction 221429_x_at NM_031274 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031274.1 /DEF=Homo sapiens testis expressed sequence 13A (TEX13A), mRNA. /FEA=CDS /GEN=TEX13A /PROD=testis expressed sequence 13A /DB_XREF=gi:13775179 /FL=gb:NM_031274.1 NM_031274 testis expressed 13A TEX13A 56157 NM_001291277 /// NM_031274 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221430_s_at NM_030963 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030963.1 /DEF=Homo sapiens hypothetical protein DKFZp434O1427 (DKFZP434O1427), mRNA. /FEA=CDS /GEN=DKFZP434O1427 /PROD=hypothetical protein DKFZp434O1427 /DB_XREF=gi:13624336 /FL=gb:NM_030963.1 NM_030963 ring finger protein 146 RNF146 81847 NM_001242844 /// NM_001242845 /// NM_001242846 /// NM_001242847 /// NM_001242848 /// NM_001242849 /// NM_001242850 /// NM_001242851 /// NM_001242852 /// NM_030963 /// NR_045102 /// NR_045103 /// XM_006715571 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072572 // poly-ADP-D-ribose binding // inferred from direct assay 221431_s_at NM_030959 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030959.1 /DEF=Homo sapiens olfactory receptor, family 12, subfamily D member 3 (OR12D3), mRNA. /FEA=CDS /GEN=OR12D3 /PROD=olfactory receptor, family 12, subfamily Dmember 3 /DB_XREF=gi:13624334 /FL=gb:NM_030959.1 NM_030959 olfactory receptor, family 12, subfamily D, member 3 OR12D3 81797 NM_030959 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221432_s_at NM_031212 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031212.1 /DEF=Homo sapiens hypothetical protein NPD016 (NPD016), mRNA. /FEA=CDS /GEN=NPD016 /PROD=hypothetical protein NPD016 /DB_XREF=gi:13654281 /FL=gb:NM_031212.1 NM_031212 solute carrier family 25 (mitochondrial iron transporter), member 28 SLC25A28 81894 NM_031212 /// XM_005270208 /// XM_005270209 /// XM_005270210 /// XM_005270211 /// XM_006718004 /// XM_006718005 /// XM_006718006 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221433_at NM_019113 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019113.1 /DEF=Homo sapiens fibroblast growth factor 21 (FGF21), mRNA. /FEA=CDS /GEN=FGF21 /PROD=fibroblast growth factor 21 /DB_XREF=gi:9506596 /UG=Hs.283015 fibroblast growth factor 21 /FL=gb:AB021975.1 gb:NM_019113.1 NM_019113 fibroblast growth factor 21 FGF21 26291 NM_019113 /// XM_005258731 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0010988 // regulation of low-density lipoprotein particle clearance // non-traceable author statement /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005104 // fibroblast growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 221434_s_at NM_031210 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031210.1 /DEF=Homo sapiens hypothetical protein DC50 (DC50), mRNA. /FEA=CDS /GEN=DC50 /PROD=hypothetical protein DC50 /DB_XREF=gi:13654277 /FL=gb:NM_031210.1 NM_031210 SRA stem-loop interacting RNA binding protein SLIRP 81892 NM_001267863 /// NM_001267864 /// NM_031210 /// NR_052025 0000961 // negative regulation of mitochondrial RNA catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221435_x_at NM_031207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031207.1 /DEF=Homo sapiens hypothetical protein HT036 (HT036), mRNA. /FEA=CDS /GEN=HT036 /PROD=hypothetical protein HT036 /DB_XREF=gi:13654271 /FL=gb:NM_031207.1 NM_031207 hydroxypyruvate isomerase (putative) HYI 81888 NM_001190880 /// NM_001243526 /// NM_031207 /// XM_005271239 /// XM_005271240 /// XM_006710937 0008152 // metabolic process // inferred from electronic annotation 0008903 // hydroxypyruvate isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 221436_s_at NM_031299 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031299.1 /DEF=Homo sapiens hypothetical protein MGC2577 (MGC2577), mRNA. /FEA=CDS /GEN=MGC2577 /PROD=hypothetical protein MGC2577 /DB_XREF=gi:13876383 /FL=gb:NM_031299.1 NM_031299 cell division cycle associated 3 CDCA3 83461 NM_031299 /// XM_005253795 /// XR_242988 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 221437_s_at NM_031280 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031280.1 /DEF=Homo sapiens mitochondrial ribosomal protein S15 (MRPS15), mRNA. /FEA=CDS /GEN=MRPS15 /PROD=mitochondrial ribosomal protein S15 /DB_XREF=gi:13775191 /FL=gb:NM_031280.1 NM_031280 mitochondrial ribosomal protein S15 MRPS15 64960 NM_031280 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 221438_s_at NM_031275 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031275.1 /DEF=Homo sapiens testis expressed sequence 12 (TEX12), mRNA. /FEA=CDS /GEN=TEX12 /PROD=testis expressed sequence 12 /DB_XREF=gi:13775181 /FL=gb:NM_031275.1 NM_031275 testis expressed 12 TEX12 56158 NM_031275 0000795 // synaptonemal complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221439_at NM_006606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006606.1 /DEF=Homo sapiens retinoblastoma-binding protein 9 (RBBP9), mRNA. /FEA=CDS /GEN=RBBP9 /PROD=retinoblastoma-binding protein 9 /DB_XREF=gi:5730004 /UG=Hs.248211 retinoblastoma-binding protein 9 /FL=gb:AF039564.1 gb:NM_006606.1 NM_006606 retinoblastoma binding protein 9 RBBP9 10741 NM_006606 /// NM_153328 /// XM_005260652 0008152 // metabolic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 221440_s_at NM_006606 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_006606.1 /DEF=Homo sapiens retinoblastoma-binding protein 9 (RBBP9), mRNA. /FEA=CDS /GEN=RBBP9 /PROD=retinoblastoma-binding protein 9 /DB_XREF=gi:5730004 /UG=Hs.248211 retinoblastoma-binding protein 9 /FL=gb:AF039564.1 gb:NM_006606.1 NM_006606 retinoblastoma binding protein 9 RBBP9 10741 NM_006606 /// NM_153328 /// XM_005260652 0008152 // metabolic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221441_at NM_005315 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005315.1 /DEF=Homo sapiens goosecoid-like (GSCL), mRNA. /FEA=CDS /GEN=GSCL /PROD=goosecoid-like /DB_XREF=gi:4885362 /UG=Hs.248132 goosecoid-like /FL=gb:NM_005315.1 NM_005315 goosecoid homeobox 2 GSC2 2928 NM_005315 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221442_at NM_019888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019888.1 /DEF=Homo sapiens melanocortin 3 receptor (MC3R), mRNA. /FEA=CDS /GEN=MC3R /PROD=melanocortin 3 receptor /DB_XREF=gi:9845270 /UG=Hs.248018 melanocortin 3 receptor /FL=gb:NM_019888.1 NM_019888 melanocortin 3 receptor MC3R 4159 NM_019888 0002027 // regulation of heart rate // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0042309 // homoiothermy // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004980 // melanocyte-stimulating hormone receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042923 // neuropeptide binding // inferred from physical interaction 221443_x_at NM_015893 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_015893.1 /DEF=Homo sapiens preproprolactin-releasing peptide (LOC51052), mRNA. /FEA=CDS /GEN=LOC51052 /PROD=preproprolactin-releasing peptide /DB_XREF=gi:7705679 /UG=Hs.247710 preproprolactin-releasing peptide /FL=gb:AB015419.1 gb:NM_015893.1 NM_015893 prolactin releasing hormone PRLH 51052 NM_015893 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0002023 // reduction of food intake in response to dietary excess // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0048483 // autonomic nervous system development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0031861 // prolactin-releasing peptide receptor binding // inferred from electronic annotation 221444_at NM_016945 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016945.1 /DEF=Homo sapiens taste receptor, type 2, member 16 (TAS2R16), mRNA. /FEA=CDS /GEN=TAS2R16 /PROD=taste receptor T2R16 /DB_XREF=gi:8394394 /UG=Hs.272395 taste receptor, type 2, member 16 /FL=gb:NM_016945.1 NM_016945 taste receptor, type 2, member 16 TAS2R16 50833 NM_016945 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred by curator /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0033038 // bitter taste receptor activity // inferred from direct assay 221445_at NM_012352 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012352.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily A, member 2 (OR1A2), mRNA. /FEA=CDS /GEN=OR1A2 /PROD=olfactory receptor, family 1, subfamily A,member 2 /DB_XREF=gi:6912551 /UG=Hs.258588 olfactory receptor, family 1, subfamily A, member 2 /FL=gb:NM_012352.1 NM_012352 olfactory receptor, family 1, subfamily A, member 2 OR1A2 26189 NM_012352 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221446_at NM_021794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021794.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 30 (ADAM30), transcript variant 1, mRNA. /FEA=CDS /GEN=ADAM30 /PROD=a disintegrin and metalloproteinase domain 30,isoform 1 preproprotein /DB_XREF=gi:11497608 /UG=Hs.283011 a disintegrin and metalloproteinase domain 30 /FL=gb:NM_021794.1 gb:AF171932.1 gb:AF171933.1 gb:NM_020334.1 NM_021794 ADAM metallopeptidase domain 30 ADAM30 11085 NM_021794 0006508 // proteolysis // inferred from electronic annotation /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0032504 // multicellular organism reproduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221447_s_at NM_031302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031302.1 /DEF=Homo sapiens gycosyltransferase (LOC83468), mRNA. /FEA=CDS /GEN=LOC83468 /PROD=gycosyltransferase /DB_XREF=gi:13775225 /FL=gb:NM_031302.1 NM_031302 glycosyltransferase 8 domain containing 2 GLT8D2 83468 NM_031302 /// XM_005269171 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 221448_s_at NM_031271 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_031271.1 /DEF=Homo sapiens testis expressed sequence 15 (TEX15), mRNA. /FEA=CDS /GEN=TEX15 /PROD=testis expressed sequence 15 /DB_XREF=gi:13775173 /FL=gb:NM_031271.1 NM_031271 testis expressed 15 TEX15 56154 NM_031271 /// XM_005273575 /// XM_005273576 /// XM_006716369 /// XM_006716370 0007129 // synapsis // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0034502 // protein localization to chromosome // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 221449_s_at NM_030790 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030790.1 /DEF=Homo sapiens hypothetical protein CDA08 (CDA08), mRNA. /FEA=CDS /GEN=CDA08 /PROD=hypothetical protein CDA08 /DB_XREF=gi:13540566 /FL=gb:NM_030790.1 NM_030790 integrin alpha FG-GAP repeat containing 1 ITFG1 81533 NM_030790 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221450_x_at NM_018933 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_018933.1 /DEF=Homo sapiens protocadherin beta 13 (PCDHB13), mRNA. /FEA=CDS /GEN=PCDHB13 /PROD=protocadherin beta 13 /DB_XREF=gi:11036653 /UG=Hs.283803 protocadherin beta 13 /FL=gb:NM_018933.1 gb:AF152492.1 NM_018933 protocadherin beta 13 PCDHB13 56123 NM_018933 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 221451_s_at NM_030903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030903.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily W, member 1 (OR2W1), mRNA. /FEA=CDS /GEN=OR2W1 /PROD=olfactory receptor, family 2, subfamily W,member 1 /DB_XREF=gi:13624328 /FL=gb:NM_030903.1 NM_030903 olfactory receptor, family 2, subfamily W, member 1 OR2W1 26692 NM_030903 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221452_s_at NM_030969 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030969.1 /DEF=Homo sapiens hypothetical protein MGC1223 (MGC1223), mRNA. /FEA=CDS /GEN=MGC1223 /PROD=hypothetical protein MGC1223 /DB_XREF=gi:13624338 /FL=gb:NM_030969.1 NM_030969 transmembrane protein 14B TMEM14B 81853 NM_001127711 /// NM_001286484 /// NM_001286488 /// NM_001286489 /// NM_030969 /// NR_104454 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221453_at NM_021176 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_021176.1 /DEF=Homo sapiens islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), mRNA. /FEA=CDS /GEN=IGRP /PROD=islet-specific glucose-6-phosphatase catalyticsubunit-related protein /DB_XREF=gi:10863974 /UG=Hs.283963 islet-specific glucose-6-phosphatase catalytic subunit-related protein /FL=gb:NM_021176.1 NM_021176 glucose-6-phosphatase, catalytic, 2 G6PC2 57818 NM_001081686 /// NM_021176 0005975 // carbohydrate metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004346 // glucose-6-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221454_at NM_014204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014204.2 /DEF=Homo sapiens BCL2-related ovarian killer (BOK), mRNA. /FEA=CDS /GEN=BOK /PROD=BCL2-related ovarian killer /DB_XREF=gi:10092609 /UG=Hs.307355 BCL2-related ovarian killer /FL=gb:NM_014204.2 gb:AF089746.1 NM_014204 0006915 // apoptotic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 221455_s_at NM_030753 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_030753.1 /DEF=Homo sapiens wingless-type MMTV integration site family, member 3 (WNT3), mRNA. /FEA=CDS /GEN=WNT3 /PROD=wingless-type MMTV integration site family,member 3 /DB_XREF=gi:13540476 /FL=gb:NM_030753.1 NM_030753 uncharacterized LOC101929777 /// wingless-type MMTV integration site family, member 3 LOC101929777 /// WNT3 7473 /// 101929777 NM_030753 /// XR_247456 /// XR_424836 /// XR_429986 /// XR_430905 /// XR_433406 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0044338 // canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation // inferred from mutant phenotype /// 0044339 // canonical Wnt signaling pathway involved in osteoblast differentiation // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048697 // positive regulation of collateral sprouting in absence of injury // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0060064 // Spemann organizer formation at the anterior end of the primitive streak // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060173 // limb development // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from expression pattern /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred by curator 221456_at NM_016943 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_016943.1 /DEF=Homo sapiens taste receptor, type 2, member 3 (TAS2R3), mRNA. /FEA=CDS /GEN=TAS2R3 /PROD=taste receptor T2R3 /DB_XREF=gi:8394397 /UG=Hs.272386 taste receptor, type 2, member 3 /FL=gb:NM_016943.1 NM_016943 taste receptor, type 2, member 3 TAS2R3 50831 NM_016943 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // traceable author statement /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement /// 0033038 // bitter taste receptor activity // inferred from direct assay 221457_s_at NM_019602 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_019602.1 /DEF=Homo sapiens butyrophilin-like 2 (MHC class II associated) (BTNL2), mRNA. /FEA=CDS /GEN=BTNL2 /PROD=butyrophilin-like 2 (MHC class II associated) /DB_XREF=gi:9624968 /UG=Hs.247808 butyrophilin-like 2 (MHC class II associated) /FL=gb:NM_019602.1 NM_019602 butyrophilin-like 2 (MHC class II associated) BTNL2 56244 NM_019602 /// XM_006726138 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221458_at NM_000866 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_000866.1 /DEF=Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1F (HTR1F), mRNA. /FEA=CDS /GEN=HTR1F /PROD=5-hydroxytryptamine (serotonin) receptor 1F /DB_XREF=gi:10835196 /UG=Hs.248136 5-hydroxytryptamine (serotonin) receptor 1F /FL=gb:NM_000866.1 NM_000866 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled HTR1F 3355 NM_000866 /// XM_005264747 /// XM_005264748 /// XM_005264749 /// XM_005264750 /// XM_005264751 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007210 // serotonin receptor signaling pathway // inferred from direct assay /// 0007210 // serotonin receptor signaling pathway // inferred from electronic annotation /// 0007210 // serotonin receptor signaling pathway // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004993 // serotonin receptor activity // inferred from direct assay /// 0004993 // serotonin receptor activity // inferred from mutant phenotype /// 0051378 // serotonin binding // inferred from direct assay 221459_at NM_003967 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003967.1 /DEF=Homo sapiens putative neurotransmitter receptor (PNR), mRNA. /FEA=CDS /GEN=PNR /PROD=putative neurotransmitter receptor /DB_XREF=gi:4505924 /UG=Hs.248198 putative neurotransmitter receptor /FL=gb:AF021818.1 gb:NM_003967.1 NM_003967 trace amine associated receptor 5 TAAR5 9038 NM_003967 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007606 // sensory perception of chemical stimulus // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator 0001594 // trace-amine receptor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 1990081 // trimethylamine receptor activity // inferred from direct assay 221460_at NM_012368 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_012368.1 /DEF=Homo sapiens olfactory receptor, family 2, subfamily C, member 1 (OR2C1), mRNA. /FEA=CDS /GEN=OR2C1 /PROD=olfactory receptor, family 2, subfamily C,member 1 /DB_XREF=gi:6912555 /UG=Hs.258574 olfactory receptor, family 2, subfamily C, member 1 /FL=gb:NM_012368.1 NM_012368 olfactory receptor, family 2, subfamily C, member 1 OR2C1 4993 NM_012368 /// XM_006720887 /// XM_006720888 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from electronic annotation 221461_at NM_023917 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_023917.1 /DEF=Homo sapiens taste receptor, family B, member 6 (TRB6), mRNA. /FEA=CDS /GEN=TRB6 /PROD=taste receptor, family B, member 6 /DB_XREF=gi:12965171 /UG=Hs.272391 taste receptor, type 2, member 9 /FL=gb:NM_023917.1 NM_023917 taste receptor, type 2, member 9 TAS2R9 50835 NM_023917 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0050912 // detection of chemical stimulus involved in sensory perception of taste // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0008527 // taste receptor activity // traceable author statement 221462_x_at NM_017509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_017509.1 /DEF=Homo sapiens ACO for serine protease homologue (HSRNASPH), mRNA. /FEA=CDS /GEN=HSRNASPH /PROD=ACO for serine protease homologue /DB_XREF=gi:13399301 /UG=Hs.250770 ACO for serine protease homologue /FL=gb:NM_017509.1 NM_017509 kallikrein-related peptidase 15 KLK15 55554 NM_001277081 /// NM_001277082 /// NM_017509 /// NM_023006 /// NM_138563 /// NM_138564 /// NR_102274 /// XM_006723265 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 221463_at NM_002991 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002991.1 /DEF=Homo sapiens small inducible cytokine subfamily A (Cys-Cys), member 24 (SCYA24), mRNA. /FEA=CDS /GEN=SCYA24 /PROD=small inducible cytokine subfamily A (Cys-Cys),member 24 /DB_XREF=gi:4506838 /UG=Hs.247838 small inducible cytokine subfamily A (Cys-Cys), member 24 /FL=gb:U85768.1 gb:NM_002991.1 NM_002991 chemokine (C-C motif) ligand 24 CCL24 6369 NM_002991 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 2000418 // positive regulation of eosinophil migration // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay 221464_at NM_002548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002548.1 /DEF=Homo sapiens olfactory receptor, family 1, subfamily D, member 2 (OR1D2), mRNA. /FEA=CDS /GEN=OR1D2 /PROD=olfactory receptor, family 1, subfamily D,member 2 /DB_XREF=gi:4505516 /UG=Hs.247936 olfactory receptor, family 1, subfamily D, member 2 /FL=gb:NM_002548.1 NM_002548 olfactory receptor, family 1, subfamily D, member 2 OR1D2 4991 NM_002548 0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007338 // single fertilization // inferred from electronic annotation /// 0007608 // sensory perception of smell // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from direct assay /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // inferred from direct assay 221465_at NM_003696 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_003696.1 /DEF=Homo sapiens olfactory receptor, family 6, subfamily A, member 1 (OR6A1), mRNA. /FEA=CDS /GEN=OR6A1 /PROD=olfactory receptor, family 6, subfamily A,member 1 /DB_XREF=gi:4505520 /UG=Hs.248186 olfactory receptor, family 6, subfamily A, member 1 /FL=gb:NM_003696.1 NM_003696 olfactory receptor, family 6, subfamily A, member 2 OR6A2 8590 NM_003696 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007608 // sensory perception of smell // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // inferred from electronic annotation /// 0050911 // detection of chemical stimulus involved in sensory perception of smell // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004984 // olfactory receptor activity // non-traceable author statement 221466_at NM_002565 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_002565.1 /DEF=Homo sapiens pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2RY4), mRNA. /FEA=CDS /GEN=P2RY4 /PROD=pyrimidinergic receptor P2Y, G-protein coupled,4 /DB_XREF=gi:4505560 /UG=Hs.248157 pyrimidinergic receptor P2Y, G-protein coupled, 4 /FL=gb:NM_002565.1 NM_002565 pyrimidinergic receptor P2Y, G-protein coupled, 4 P2RY4 5030 NM_002565 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015065 // uridine nucleotide receptor activity // traceable author statement /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation /// 0045030 // UTP-activated nucleotide receptor activity // inferred from electronic annotation 221467_at NM_005912 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005912.1 /DEF=Homo sapiens melanocortin 4 receptor (MC4R), mRNA. /FEA=CDS /GEN=MC4R /PROD=melanocortin 4 receptor /DB_XREF=gi:5174532 /UG=Hs.247980 melanocortin 4 receptor /FL=gb:NM_005912.1 NM_005912 melanocortin 4 receptor MC4R 4160 NM_005912 0002024 // diet induced thermogenesis // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007631 // feeding behavior // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from mutant phenotype /// 0060259 // regulation of feeding behavior // inferred from electronic annotation /// 2000252 // negative regulation of feeding behavior // inferred from electronic annotation /// 2000821 // regulation of grooming behavior // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004977 // melanocortin receptor activity // traceable author statement /// 0004980 // melanocyte-stimulating hormone receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042923 // neuropeptide binding // inferred from physical interaction 221468_at NM_005283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_005283.1 /DEF=Homo sapiens chemokine (C motif) XC receptor 1 (CCXCR1), mRNA. /FEA=CDS /GEN=CCXCR1 /PROD=G protein-coupled receptor 5 /DB_XREF=gi:4885338 /UG=Hs.248116 chemokine (C motif) XC receptor 1 /FL=gb:NM_005283.1 NM_005283 chemokine (C motif) receptor 1 XCR1 2829 NM_001024644 /// NM_005283 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004950 // chemokine receptor activity // inferred from electronic annotation 221469_at NM_001506 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_001506.1 /DEF=Homo sapiens G protein-coupled receptor 32 (GPR32), mRNA. /FEA=CDS /GEN=GPR32 /PROD=G protein-coupled receptor 32 /DB_XREF=gi:4504092 /UG=Hs.248125 G protein-coupled receptor 32 /FL=gb:NM_001506.1 NM_001506 G protein-coupled receptor 32 GPR32 2854 NM_001506 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004982 // N-formyl peptide receptor activity // inferred from electronic annotation 221470_s_at NM_014439 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:NM_014439.1 /DEF=Homo sapiens Interleukin-1 Superfamily z (FIL1(ZETA)), mRNA. /FEA=CDS /GEN=FIL1(ZETA) /PROD=Interleukin-1 Superfamily z /DB_XREF=gi:7657093 /UG=Hs.166371 Interleukin-1 Superfamily z /FL=gb:AF201832.1 gb:NM_014439.1 NM_014439 interleukin 37 IL37 27178 NM_014439 /// NM_173202 /// NM_173203 /// NM_173204 /// NM_173205 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // non-traceable author statement /// 0005149 // interleukin-1 receptor binding // traceable author statement 221471_at AW173623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW173623 /FEA=EST /DB_XREF=gi:6439571 /DB_XREF=est:xj10a08.x1 /CLONE=IMAGE:2656790 /UG=Hs.272168 tumor differentially expressed 1 /FL=gb:U49188.1 gb:AF112227.1 gb:AF153979.1 gb:NM_006811.1 AW173623 serine incorporator 3 SERINC3 10955 NM_006811 /// NM_198941 1902237 // positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221472_at Z97053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:Z97053 /DEF=Human DNA sequence from clone RP1-179M20 on chromosome 20 Contains a 3 end of a novel gene similar to cellular retinaldehyde-binding protein, the TDE1 gene (Tumour differentially expressed 1), the PKIG gene encoding protein kinase (cAMP-dependent... /FEA=mRNA_2 /DB_XREF=gi:9650676 /UG=Hs.272168 tumor differentially expressed 1 /FL=gb:U49188.1 gb:AF112227.1 gb:AF153979.1 gb:NM_006811.1 Z97053 serine incorporator 3 SERINC3 10955 NM_006811 /// NM_198941 1902237 // positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221473_x_at U49188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U49188.1 /DEF=Human placenta (Diff33) mRNA, complete cds. /FEA=mRNA /GEN=Diff33 /DB_XREF=gi:1293562 /UG=Hs.272168 tumor differentially expressed 1 /FL=gb:U49188.1 gb:AF112227.1 gb:AF153979.1 gb:NM_006811.1 U49188 serine incorporator 3 SERINC3 10955 NM_006811 /// NM_198941 1902237 // positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221474_at U26162 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U26162.1 /DEF=Human myosin regulatory light chain mRNA, complete cds. /FEA=mRNA /PROD=myosin regulatory light chain /DB_XREF=gi:829622 /UG=Hs.180224 death-associated protein 6 /FL=gb:BC004994.1 gb:D50372.1 gb:U26162.1 U26162 myosin, light chain 12B, regulatory MYL12B 103910 NM_001144944 /// NM_001144945 /// NM_001144946 /// NM_033546 0006936 // muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221475_s_at NM_002948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_002948.1 /DEF=Homo sapiens ribosomal protein L15 (RPL15), mRNA. /FEA=CDS /GEN=RPL15 /PROD=ribosomal protein L15 /DB_XREF=gi:4506602 /UG=Hs.74267 ribosomal protein L15 /FL=gb:AF279903.1 gb:L25899.1 gb:NM_002948.1 NM_002948 ribosomal protein L15 RPL15 6138 NM_001253379 /// NM_001253380 /// NM_001253382 /// NM_001253383 /// NM_001253384 /// NM_002948 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221476_s_at AF279903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF279903.1 /DEF=Homo sapiens 60S ribosomal protein L15 (EC45) mRNA, complete cds. /FEA=mRNA /GEN=EC45 /PROD=60S ribosomal protein L15 /DB_XREF=gi:12006349 /UG=Hs.74267 ribosomal protein L15 /FL=gb:AF279903.1 gb:L25899.1 gb:NM_002948.1 AF279903 ribosomal protein L15 RPL15 6138 NM_001253379 /// NM_001253380 /// NM_001253382 /// NM_001253383 /// NM_001253384 /// NM_002948 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221477_s_at BF575213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF575213 /FEA=EST /DB_XREF=gi:11648925 /DB_XREF=est:602133624F1 /CLONE=IMAGE:4288756 /UG=Hs.177781 Homo sapiens, clone MGC:5618, mRNA, complete cds /FL=gb:BC001980.1 BF575213 uncharacterized LOC100129518 /// superoxide dismutase 2, mitochondrial LOC100129518 /// SOD2 6648 /// 100129518 NM_000636 /// NM_001024465 /// NM_001024466 /// NR_037166 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from mutant phenotype /// 0001306 // age-dependent response to oxidative stress // inferred from electronic annotation /// 0001315 // age-dependent response to reactive oxygen species // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0003032 // detection of oxygen // inferred from electronic annotation /// 0003069 // vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034021 // response to silicon dioxide // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048773 // erythrophore differentiation // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0030145 // manganese ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221478_at AL132665 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL132665.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566E034 (from clone DKFZp566E034); complete cds. /FEA=mRNA /DB_XREF=gi:6137021 /UG=Hs.132955 BCL2adenovirus E1B 19kD-interacting protein 3-like /FL=gb:AF060922.1 gb:AB004788.1 gb:AF067396.1 gb:NM_004331.1 gb:AL132665.1 AL132665 BCL2/adenovirus E1B 19kDa interacting protein 3-like BNIP3L 665 NM_004331 /// XM_005273617 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0097345 // mitochondrial outer membrane permeabilization // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from direct assay /// 0005521 // lamin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 221479_s_at AF060922 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF060922.1 /DEF=Homo sapiens clone 016a05 My020 protein mRNA, complete cds. /FEA=mRNA /PROD=My020 protein /DB_XREF=gi:12001981 /UG=Hs.132955 BCL2adenovirus E1B 19kD-interacting protein 3-like /FL=gb:AF060922.1 gb:AB004788.1 gb:AF067396.1 gb:NM_004331.1 gb:AL132665.1 AF060922 BCL2/adenovirus E1B 19kDa interacting protein 3-like BNIP3L 665 NM_004331 /// XM_005273617 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0097345 // mitochondrial outer membrane permeabilization // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from direct assay /// 0005521 // lamin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 221480_at BG180941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG180941 /FEA=EST /DB_XREF=gi:12687644 /DB_XREF=est:602327416F1 /CLONE=IMAGE:4428914 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:D55672.1 BG180941 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 221481_x_at D55672 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D55672.1 /DEF=Human mRNA for heterogeneous nuclear ribonucleoprotein D (hnRNP D), complete cds, clone cDx7. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein D (hnRNPD) /DB_XREF=gi:870744 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:D55672.1 D55672 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 221482_s_at BC003418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003418.1 /DEF=Homo sapiens, cyclic AMP phosphoprotein, 19 kD, clone MGC:5468, mRNA, complete cds. /FEA=mRNA /PROD=cyclic AMP phosphoprotein, 19 kD /DB_XREF=gi:13097335 /UG=Hs.7351 cyclic AMP phosphoprotein, 19 kD /FL=gb:BC003418.1 gb:AF084555.1 BC003418 cAMP-regulated phosphoprotein, 19kDa ARPP19 10776 NM_006628 /// XM_005254132 /// XM_005254133 /// XM_005254134 /// XM_005254135 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from direct assay /// 0046326 // positive regulation of glucose import // non-traceable author statement /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 221483_s_at AF084555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF084555.1 /DEF=Homo sapiens okadaic acid-inducible and cAMP-regulated phosphoprotein 19 (ARPP-19) mRNA, complete cds. /FEA=mRNA /GEN=ARPP-19 /PROD=okadaic acid-inducible and cAMP-regulatedphosphoprotein 19 /DB_XREF=gi:5813858 /UG=Hs.7351 cyclic AMP phosphoprotein, 19 kD /FL=gb:BC003418.1 gb:AF084555.1 AF084555 cAMP-regulated phosphoprotein, 19kDa ARPP19 10776 NM_006628 /// XM_005254132 /// XM_005254133 /// XM_005254134 /// XM_005254135 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from direct assay /// 0046326 // positive regulation of glucose import // non-traceable author statement /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 221484_at BF691447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF691447 /FEA=EST /DB_XREF=gi:11976855 /DB_XREF=est:602247615F1 /CLONE=IMAGE:4332866 /UG=Hs.107526 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 /FL=gb:AB004550.1 gb:AF038663.1 gb:NM_004776.1 BF691447 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 B4GALT5 9334 NM_004776 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221485_at AL035683 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035683 /DEF=Human DNA sequence from clone RP5-1063B2 on chromosome 20q13.1-13.2. Contains the 3 part of the gene for Beta-1,4-galactosyltransferase, ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:7288039 /UG=Hs.107526 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 /FL=gb:AB004550.1 gb:AF038663.1 gb:NM_004776.1 AL035683 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 B4GALT5 9334 NM_004776 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008378 // galactosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221486_at AF067170 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF067170.1 /DEF=Homo sapiens alpha endosulfine mRNA, complete cds. /FEA=mRNA /PROD=alpha endosulfine /DB_XREF=gi:4894373 /UG=Hs.111680 endosulfine alpha /FL=gb:AF067170.1 gb:AF157510.1 AF067170 endosulfine alpha ENSA 2029 NM_004436 /// NM_207042 /// NM_207043 /// NM_207044 /// NM_207045 /// NM_207046 /// NM_207047 /// NM_207168 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 221487_s_at AF157510 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF157510.1 /DEF=Homo sapiens beta endosulfine mRNA, complete cds. /FEA=mRNA /PROD=beta endosulfine /DB_XREF=gi:8886010 /UG=Hs.111680 endosulfine alpha /FL=gb:AF067170.1 gb:AF157510.1 AF157510 endosulfine alpha ENSA 2029 NM_004436 /// NM_207042 /// NM_207043 /// NM_207044 /// NM_207045 /// NM_207046 /// NM_207047 /// NM_207168 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 221488_s_at AF230924 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF230924.1 /DEF=Homo sapiens brain acetylcholinesterase putative membrane anchor mRNA, complete cds. /FEA=mRNA /PROD=brain acetylcholinesterase putative membraneanchor /DB_XREF=gi:7341254 /UG=Hs.107187 divalent cation tolerant protein CUTA /FL=gb:AF230924.1 AF230924 cutA divalent cation tolerance homolog (E. coli) CUTA 51596 NM_001014433 /// NM_001014837 /// NM_001014838 /// NM_001014840 /// NM_015921 /// XM_006715108 /// XM_006726096 0008104 // protein localization // inferred from direct assay /// 0010038 // response to metal ion // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 221489_s_at W48843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W48843 /FEA=EST /DB_XREF=gi:1337022 /DB_XREF=est:zc44a09.s1 /CLONE=IMAGE:325144 /UG=Hs.285814 sprouty (Drosophila) homolog 4 /FL=gb:AF227517.1 W48843 sprouty homolog 4 (Drosophila) SPRY4 81848 NM_001127496 /// NM_001293289 /// NM_001293290 /// NM_030964 /// XM_005268518 /// XM_005268519 /// XM_006714798 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221490_at AL136733 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136733.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N1010 (from clone DKFZp434N1010); complete cds. /FEA=mRNA /GEN=DKFZp434N1010 /PROD=hypothetical protein /DB_XREF=gi:12052984 /UG=Hs.75425 ubiquitin associated protein /FL=gb:AL136733.1 gb:AF222043.2 gb:NM_016525.2 AL136733 ubiquitin associated protein 1 UBAP1 51271 NM_001171201 /// NM_001171202 /// NM_001171203 /// NM_001171204 /// NM_016525 /// NR_033243 /// XM_006716779 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype 0000813 // ESCRT I complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay 221491_x_at AA807056 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA807056 /FEA=EST /DB_XREF=gi:2876632 /DB_XREF=est:oc35c12.s1 /CLONE=IMAGE:1351702 /UG=Hs.279930 major histocompatibility complex, class II, DR beta 3 /FL=gb:M27635.1 gb:NM_022555.1 gb:M26038.1 gb:U95989.1 gb:U95819.1 gb:U66825.1 AA807056 major histocompatibility complex, class II, DQ beta 1 /// major histocompatibility complex, class II, DR beta 1 /// major histocompatibility complex, class II, DR beta 3 /// major histocompatibility complex, class II, DR beta 4 /// major histocompatibility complex, class II, DR beta 5 /// major histocompatibility complex, class II, DR beta 6 (pseudogene) /// HLA class II histocompatibility antigen, DRB1-10 beta chain-like /// HLA class II histocompatibility antigen, DQ beta 1 chain-like HLA-DQB1 /// HLA-DRB1 /// HLA-DRB3 /// HLA-DRB4 /// HLA-DRB5 /// HLA-DRB6 /// LOC100996809 /// LOC101060835 3119 /// 3123 /// 3125 /// 3126 /// 3127 /// 3128 /// 100996809 /// 101060835 NM_001243961 /// NM_001243962 /// NM_001243965 /// NM_002123 /// NM_002124 /// NM_002125 /// NM_021983 /// NM_022555 /// NR_001298 /// XM_003960955 /// XM_005276082 /// XM_006710174 /// XM_006710243 /// XM_006725752 /// XM_006725860 /// XM_006725948 /// XR_247369 /// XR_247388 /// XR_247422 /// XR_426005 /// XR_430944 /// XR_430980 0002376 // immune system process // inferred from electronic annotation /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from direct assay /// 0002381 // immunoglobulin production involved in immunoglobulin mediated immune response // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from direct assay /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0006955 // immune response // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016045 // detection of bacterium // inferred from sequence or structural similarity /// 0016045 // detection of bacterium // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032673 // regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032673 // regulation of interleukin-4 production // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from mutant phenotype /// 0042088 // T-helper 1 type immune response // inferred from sequence or structural similarity /// 0042088 // T-helper 1 type immune response // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042130 // negative regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051262 // protein tetramerization // inferred from sequence or structural similarity /// 0051262 // protein tetramerization // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 2001179 // regulation of interleukin-10 secretion // inferred from sequence or structural similarity /// 2001179 // regulation of interleukin-10 secretion // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0042613 // MHC class II protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity /// 0042605 // peptide antigen binding // inferred from direct assay 221492_s_at AF202092 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF202092.1 /DEF=Homo sapiens PC3-96 mRNA, complete cds. /FEA=mRNA /PROD=PC3-96 /DB_XREF=gi:11493699 /UG=Hs.26367 PC3-96 protein /FL=gb:AF202092.1 AF202092 autophagy related 3 ATG3 64422 NM_001278712 /// NM_022488 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006501 // C-terminal protein lipidation // not recorded /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from sequence or structural similarity /// 0044804 // nucleophagy // /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0000153 // cytoplasmic ubiquitin ligase complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019776 // Atg8 ligase activity // not recorded /// 0019776 // Atg8 ligase activity // inferred from sequence or structural similarity /// 0019777 // Atg12 ligase activity // inferred from sequence or structural similarity /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 221493_at AL136629 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136629.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D152 (from clone DKFZp564D152); complete cds. /FEA=mRNA /GEN=DKFZp564D152 /PROD=hypothetical protein /DB_XREF=gi:12052783 /UG=Hs.278479 TSPY-like /FL=gb:AL136629.1 AL136629 TSPY-like 1 TSPYL1 7259 NM_003309 0005975 // carbohydrate metabolic process // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from electronic annotation /// 0030208 // dermatan sulfate biosynthetic process // inferred from direct assay /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0047757 // chondroitin-glucuronate 5-epimerase activity // inferred from direct assay /// 0047757 // chondroitin-glucuronate 5-epimerase activity // inferred from electronic annotation 221494_x_at AF085358 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF085358.1 /DEF=Homo sapiens HSPC029 mRNA, complete cds. /FEA=mRNA /PROD=HSPC029 /DB_XREF=gi:5114050 /UG=Hs.283781 muscle specific gene /FL=gb:NM_013234.1 gb:BC001031.1 gb:AF315506.1 gb:AB019392.1 gb:AF077051.1 gb:AF085358.1 AF085358 eukaryotic translation initiation factor 3, subunit K EIF3K 27335 NM_013234 /// XM_006723147 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation 221495_s_at AF322111 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF322111.1 /DEF=Homo sapiens FKSG26 mRNA, complete cds. /FEA=mRNA /PROD=FKSG26 /DB_XREF=gi:12276139 /UG=Hs.227835 KIAA1049 protein /FL=gb:AF322111.1 gb:BC000959.1 AF322111 transcription factor 25 (basic helix-loop-helix) TCF25 22980 NM_014972 /// XM_005256297 /// XM_005256298 /// XM_005256299 /// XM_005256300 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 221496_s_at D64109 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:D64109.1 /DEF=Homo sapiens mRNA for tob family, complete cds. /FEA=mRNA /PROD=tob family /DB_XREF=gi:1469154 /UG=Hs.4994 transducer of ERBB2, 2 /FL=gb:D64109.1 gb:AB035207.1 gb:NM_016272.1 D64109 transducer of ERBB2, 2 TOB2 10766 NM_016272 /// XM_005261315 /// XM_006724105 0007292 // female gamete generation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // inferred from electronic annotation 221497_x_at BC005369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005369.1 /DEF=Homo sapiens, chromosome 1 open reading frame 12, clone MGC:12484, mRNA, complete cds. /FEA=mRNA /PROD=chromosome 1 open reading frame 12 /DB_XREF=gi:13529208 /UG=Hs.6523 chromosome 1 open reading frame 12 /FL=gb:AF229245.1 gb:AF277176.1 gb:NM_022051.1 gb:BC005369.1 BC005369 egl-9 family hypoxia-inducible factor 1 EGLN1 54583 NM_022051 /// XM_005273166 /// XM_005273167 /// XM_006711782 0001666 // response to hypoxia // inferred from direct assay /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0030821 // negative regulation of cAMP catabolic process // inferred from sequence or structural similarity /// 0032364 // oxygen homeostasis // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0055008 // cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071731 // response to nitric oxide // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0031543 // peptidyl-proline dioxygenase activity // traceable author statement /// 0031545 // peptidyl-proline 4-dioxygenase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 221498_at BF939727 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939727 /FEA=EST /DB_XREF=gi:12356970 /DB_XREF=est:nac82b01.x1 /CLONE=IMAGE:3440593 /UG=Hs.67619 hypothetical protein My014 /FL=gb:AF060509.1 BF939727 sorting nexin family member 27 SNX27 81609 NM_030918 /// XM_005245509 /// XM_005245510 /// XM_005245511 /// XM_005245512 0001770 // establishment of natural killer cell polarity // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 221499_s_at AK026970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026970.1 /DEF=Homo sapiens cDNA: FLJ23317 fis, clone HEP12062, highly similar to AF008936 Homo sapiens syntaxin-16B mRNA. /FEA=mRNA /DB_XREF=gi:10439960 /UG=Hs.102178 syntaxin 16 /FL=gb:AF008936.1 AK026970 syntaxin 16 STX16 8675 NM_001001433 /// NM_001001434 /// NM_001134772 /// NM_001134773 /// NM_001204868 /// NM_003763 /// NR_037941 /// NR_037942 /// NR_037943 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 221500_s_at BE782754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE782754 /FEA=EST /DB_XREF=gi:10203952 /DB_XREF=est:601471903F1 /CLONE=IMAGE:3874921 /UG=Hs.102178 syntaxin 16 /FL=gb:AF008936.1 BE782754 syntaxin 16 STX16 8675 NM_001001433 /// NM_001001434 /// NM_001134772 /// NM_001134773 /// NM_001204868 /// NM_003763 /// NR_037941 /// NR_037942 /// NR_037943 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 221501_x_at AF229069 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229069.1 /DEF=Homo sapiens KIAA0220-like protein mRNA, complete cds. /FEA=mRNA /PROD=KIAA0220-like protein /DB_XREF=gi:8980670 /UG=Hs.251928 nuclear pore complex interacting protein /FL=gb:AF229069.1 AF229069 polycystin-1-like /// nuclear pore complex interacting protein family, member A1 /// nuclear pore complex interacting protein family, member A2 /// nuclear pore complex interacting protein family, member A3 /// nuclear pore complex interacting protein family, member A5 /// nuclear pore complex interacting protein family, member A7 /// nuclear pore complex interacting protein family, member A8 /// polycystic kidney disease 1 (autosomal dominant) pseudogene 1 LOC101930075 /// NPIPA1 /// NPIPA2 /// NPIPA3 /// NPIPA5 /// NPIPA7 /// NPIPA8 /// PKD1P1 9284 /// 339044 /// 642778 /// 642799 /// 100288332 /// 101059938 /// 101059953 /// 101930075 NM_001277323 /// NM_001277324 /// NM_001277325 /// NM_001282507 /// NM_001282511 /// NM_006985 /// NR_036447 /// XM_005255019 /// XM_005255020 /// XM_005255021 /// XM_005255024 /// XM_005255484 /// XM_005255485 /// XM_005255486 /// XM_005255487 /// XM_005255488 /// XM_005255489 /// XM_005255490 /// XM_005255491 /// XM_005255492 /// XM_005255694 /// XM_005255695 /// XM_005255735 /// XM_005255737 /// XM_005255738 /// XM_005276493 /// XM_006720823 /// XM_006720824 /// XM_006720825 /// XM_006720826 /// XM_006720827 /// XM_006720828 /// XM_006720829 /// XM_006720830 /// XM_006720916 /// XM_006720917 /// XM_006720979 /// XM_006720980 /// XM_006725185 /// XM_006725186 /// XM_006725187 /// XM_006725188 /// XM_006725189 /// XM_006725190 /// XM_006725191 /// XM_006725205 /// XM_006725206 /// XM_006725207 /// XM_006725208 /// XM_006725209 /// XM_006725210 /// XM_006725211 /// XM_006725212 /// XM_006725213 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 221502_at AL120704 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL120704 /FEA=EST /DB_XREF=gi:5926603 /DB_XREF=est:DKFZp762C1712_r1 /CLONE=DKFZp762C1712 /UG=Hs.3886 karyopherin alpha 3 (importin alpha 4) /FL=gb:D89618.1 gb:AF034756.1 gb:NM_002267.1 AL120704 karyopherin alpha 3 (importin alpha 4) KPNA3 3839 NM_002267 0006461 // protein complex assembly // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0075732 // viral penetration into host nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 221503_s_at AF034756 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF034756.1 /DEF=Homo sapiens importin-alpha homolog (SRP1gamma) mRNA, complete cds. /FEA=mRNA /GEN=SRP1gamma /PROD=importin-alpha homolog /DB_XREF=gi:2654138 /UG=Hs.3886 karyopherin alpha 3 (importin alpha 4) /FL=gb:D89618.1 gb:AF034756.1 gb:NM_002267.1 AF034756 karyopherin alpha 3 (importin alpha 4) KPNA3 3839 NM_002267 0006461 // protein complex assembly // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0075732 // viral penetration into host nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 221504_s_at AF112204 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF112204.1 /DEF=Homo sapiens Vacuolar proton pump subunit SFD alpha isoform mRNA, complete cds. /FEA=mRNA /PROD=Vacuolar proton pump subunit SFD alpha isoform /DB_XREF=gi:6563195 /UG=Hs.19575 CGI-11 protein /FL=gb:AF298777.1 gb:AF132945.1 gb:AF112204.1 gb:NM_015941.1 AF112204 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H ATP6V1H 51606 NM_015941 /// NM_213619 /// NM_213620 /// XM_006716455 0006200 // ATP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006897 // endocytosis // inferred from direct assay /// 0007035 // vacuolar acidification // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // non-traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0000221 // vacuolar proton-transporting V-type ATPase, V1 domain // non-traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // non-traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 221505_at AW612574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW612574 /FEA=EST /DB_XREF=gi:7317760 /DB_XREF=est:hh05b12.x1 /CLONE=IMAGE:2954207 /UG=Hs.71331 hypothetical protein MGC5350 /FL=gb:BC003380.1 AW612574 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E ANP32E 81611 NM_001136478 /// NM_001136479 /// NM_001280559 /// NM_001280560 /// NM_030920 /// XM_005245513 /// XM_005245514 /// XR_426799 /// XR_426800 0016568 // chromatin modification // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0043486 // histone exchange // inferred from direct assay 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0042393 // histone binding // inferred from direct assay 221506_s_at BG258639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG258639 /FEA=EST /DB_XREF=gi:12768455 /DB_XREF=est:602380357F1 /CLONE=IMAGE:4510766 /UG=Hs.278378 karyopherin beta 2b, transportin /FL=gb:AF019039.1 BG258639 transportin 2 TNPO2 30000 NM_001136195 /// NM_001136196 /// NM_013433 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 221507_at BG258639 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG258639 /FEA=EST /DB_XREF=gi:12768455 /DB_XREF=est:602380357F1 /CLONE=IMAGE:4510766 /UG=Hs.278378 karyopherin beta 2b, transportin /FL=gb:AF019039.1 BG258639 transportin 2 TNPO2 30000 NM_001136195 /// NM_001136196 /// NM_013433 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 221508_at AF181985 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF181985.1 /DEF=Homo sapiens serinethreonine kinase (KDS) mRNA, complete cds. /FEA=mRNA /GEN=KDS /PROD=serinethreonine kinase /DB_XREF=gi:6708149 /UG=Hs.12040 STE20-like kinase /FL=gb:BC002756.1 gb:AF181985.1 AF181985 TAO kinase 3 TAOK3 51347 NM_016281 /// XM_005253897 /// XM_005253898 /// XM_006719445 /// XM_006719446 0000165 // MAPK cascade // inferred from mutant phenotype /// 0000186 // activation of MAPKK activity // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // not recorded /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from direct assay /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221509_at AB014731 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB014731.1 /DEF=Homo sapiens mRNA for SMAP-3, complete cds. /FEA=mRNA /GEN=smap-3 /PROD=SMAP-3 /DB_XREF=gi:12248760 /UG=Hs.22393 density-regulated protein /FL=gb:AB014731.1 AB014731 density-regulated protein DENR 8562 NM_003677 0001731 // formation of translation preinitiation complex // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006413 // translational initiation // inferred from electronic annotation /// 0032790 // ribosome disassembly // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221510_s_at AF158555 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF158555.1 /DEF=Homo sapiens glutaminase C mRNA, complete cds. /FEA=mRNA /PROD=glutaminase C /DB_XREF=gi:5690371 /UG=Hs.239189 glutaminase /FL=gb:AF158555.1 gb:AF097492.1 AF158555 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 221511_x_at AB033080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033080.1 /DEF=Homo sapiens mRNA for KIAA1254 protein, partial cds. /FEA=mRNA /GEN=KIAA1254 /PROD=KIAA1254 protein /DB_XREF=gi:6330892 /UG=Hs.82506 KIAA1254 protein /FL=gb:AF212228.1 AB033080 cell cycle progression 1 /// DYX1C1-CCPG1 readthrough (NMD candidate) CCPG1 /// DYX1C1-CCPG1 9236 /// 100533483 NM_001204450 /// NM_001204451 /// NM_004748 /// NM_020739 /// NR_037923 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001106 // regulation of Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221512_at AL136683 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136683.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564D0478 (from clone DKFZp564D0478); complete cds. /FEA=mRNA /GEN=DKFZp564D0478 /PROD=hypothetical protein /DB_XREF=gi:12052889 /UG=Hs.321214 Homo sapiens mRNA; cDNA DKFZp564D0478 (from clone DKFZp564D0478); complete cds /FL=gb:AL136683.1 AL136683 transmembrane protein 222 TMEM222 84065 NM_032125 /// NR_037576 /// NR_037577 /// NR_037580 /// XM_006710942 /// XM_006710943 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221513_s_at BC001149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001149.1 /DEF=Homo sapiens, Similar to KIAA0266 gene product, clone MGC:1291, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0266 gene product /DB_XREF=gi:12654624 /UG=Hs.271926 serologically defined colon cancer antigen 16 /FL=gb:BC001149.1 BC001149 ALG11, alpha-1,2-mannosyltransferase /// UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) /// UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) ALG11 /// UTP14A /// UTP14C 9724 /// 10813 /// 440138 NM_001004127 /// NM_001166221 /// NM_006649 /// NM_021645 /// NR_036571 /// XM_005262363 0006364 // rRNA processing // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0004377 // GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221514_at BC001149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001149.1 /DEF=Homo sapiens, Similar to KIAA0266 gene product, clone MGC:1291, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA0266 gene product /DB_XREF=gi:12654624 /UG=Hs.271926 serologically defined colon cancer antigen 16 /FL=gb:BC001149.1 BC001149 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) UTP14A 10813 NM_001166221 /// NM_006649 /// XM_005262363 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221515_s_at BC001214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001214.1 /DEF=Homo sapiens, CGI-68 protein, clone MGC:682, mRNA, complete cds. /FEA=mRNA /PROD=CGI-68 protein /DB_XREF=gi:12654744 /UG=Hs.8054 CGI-68 protein /FL=gb:BC001214.1 gb:AF151826.1 gb:NM_016015.1 BC001214 leucine carboxyl methyltransferase 1 LCMT1 51451 NM_001032391 /// NM_016309 /// XM_005255354 /// XM_006721050 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from mutant phenotype /// 0006481 // C-terminal protein methylation // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0003880 // protein C-terminal carboxyl O-methyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 221516_s_at BC002587 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002587.1 /DEF=Homo sapiens, hypothetical protein, clone MGC:1067, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:12803520 /UG=Hs.83869 hypothetical protein /FL=gb:BC002587.1 BC002587 mitochondrial elongation factor 1 MIEF1 54471 NM_019008 /// XM_005261652 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005777 // peroxisome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019003 // GDP binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 221517_s_at AF105421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF105421.1 /DEF=Homo sapiens vitamin D3 receptor interacting protein (DRIP80) mRNA, complete cds. /FEA=mRNA /GEN=DRIP80 /PROD=vitamin D3 receptor interacting protein /DB_XREF=gi:4838128 /UG=Hs.22630 cofactor required for Sp1 transcriptional activation, subunit 6 (77kD) /FL=gb:AF105421.1 AF105421 mediator complex subunit 17 MED17 9440 NM_004268 /// XR_247218 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 221518_s_at BE966019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966019 /FEA=EST /DB_XREF=gi:11770993 /DB_XREF=est:601659921R1 /CLONE=IMAGE:3905741 /UG=Hs.300700 hypothetical protein FLJ20727 /FL=gb:BC000226.1 BE966019 ubiquitin specific peptidase 47 USP47 55031 NM_001282659 /// NM_017944 /// XM_005252997 0006281 // DNA repair // inferred from electronic annotation /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0034644 // cellular response to UV // inferred from sequence or structural similarity /// 0035520 // monoubiquitinated protein deubiquitination // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0071987 // WD40-repeat domain binding // inferred from physical interaction 221519_at AF281859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF281859.1 /DEF=Homo sapiens dactylin mRNA, complete cds. /FEA=mRNA /PROD=dactylin /DB_XREF=gi:10764487 /UG=Hs.24307 split handfoot malformation (ectrodactyly) type 3 /FL=gb:AF281859.1 gb:NM_022039.1 AF281859 F-box and WD repeat domain containing 4 FBXW4 6468 NM_022039 /// XM_005270053 /// XR_246102 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // non-traceable author statement /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0000151 // ubiquitin ligase complex // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 221520_s_at BC001651 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001651.1 /DEF=Homo sapiens, hypothetical protein FLJ10468, clone MGC:2726, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10468 /DB_XREF=gi:12804484 /UG=Hs.48855 hypothetical protein FLJ10468 /FL=gb:BC000703.1 gb:BC001651.1 BC001651 cell division cycle associated 8 CDCA8 55143 NM_001256875 /// NM_018101 0000089 // mitotic metaphase // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010369 // chromocenter // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221521_s_at BC003186 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003186.1 /DEF=Homo sapiens, HSPC037 protein, clone MGC:673, mRNA, complete cds. /FEA=mRNA /PROD=HSPC037 protein /DB_XREF=gi:13112024 /UG=Hs.108196 HSPC037 protein /FL=gb:BC003186.1 gb:AF201939.1 BC003186 GINS complex subunit 2 (Psf2 homolog) GINS2 51659 NM_016095 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction 221522_at AL136784 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136784.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L0718 (from clone DKFZp434L0718); complete cds. /FEA=mRNA /GEN=DKFZp434L0718 /PROD=hypothetical protein /DB_XREF=gi:12053080 /UG=Hs.59236 Homo sapiens mRNA; cDNA DKFZp434L0718 (from clone DKFZp434L0718); complete cds /FL=gb:AL136784.1 AL136784 ankyrin repeat domain 27 (VPS9 domain) ANKRD27 84079 NM_032139 /// XM_005259310 /// XM_006723412 /// XM_006723413 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045022 // early endosome to late endosome transport // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221523_s_at AL138717 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL138717 /DEF=Human DNA sequence from clone RP11-11D8 on chromosome 6 Contains the 5 end of the gene for a yeast ubiquitin conjugating enzyme UBC6 homolog, the gene for a possible GTP binding protein, a NACA (nascent-polypeptide-associated complex alpha polype... /FEA=mRNA_2 /DB_XREF=gi:8894207 /UG=Hs.238679 Rag D protein /FL=gb:NM_021244.1 gb:AF272036.1 gb:BC003088.1 AL138717 Ras-related GTP binding D RRAGD 58528 NM_021244 /// XM_005248755 0032008 // positive regulation of TOR signaling // non-traceable author statement /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 221524_s_at AF272036 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF272036.1 /DEF=Homo sapiens Rag D mRNA, complete cds. /FEA=mRNA /PROD=Rag D /DB_XREF=gi:11181619 /UG=Hs.238679 Rag D protein /FL=gb:NM_021244.1 gb:AF272036.1 gb:BC003088.1 AF272036 Ras-related GTP binding D RRAGD 58528 NM_021244 /// XM_005248755 0032008 // positive regulation of TOR signaling // non-traceable author statement /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 221525_at AL136572 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136572.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761I2123 (from clone DKFZp761I2123); complete cds. /FEA=mRNA /GEN=DKFZp761I2123 /PROD=hypothetical protein /DB_XREF=gi:13276646 /UG=Hs.77978 Homo sapiens mRNA; cDNA DKFZp761I2123 (from clone DKFZp761I2123); complete cds /FL=gb:AL136572.1 AL136572 zinc finger, MIZ-type containing 2 ZMIZ2 83637 NM_031449 /// NM_174929 /// XM_005249866 /// XM_005249867 /// XM_005249868 /// XM_005249869 /// XM_005249870 /// XM_005249871 /// XM_005249872 /// XM_005249873 /// XM_005249874 /// XM_005249875 /// XM_006715787 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043596 // nuclear replication fork // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221526_x_at AW452651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW452651 /FEA=EST /DB_XREF=gi:6993427 /DB_XREF=est:UI-H-BI3-alu-g-02-0-UI.s1 /CLONE=IMAGE:3068738 /UG=Hs.72249 three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect) /FL=gb:AF196185.1 AW452651 par-3 family cell polarity regulator PARD3 56288 NM_001184785 /// NM_001184786 /// NM_001184787 /// NM_001184788 /// NM_001184789 /// NM_001184790 /// NM_001184791 /// NM_001184792 /// NM_001184793 /// NM_001184794 /// NM_019619 /// XM_005252528 /// XM_005252530 /// XM_005252531 /// XM_005252532 /// XM_005252534 /// XM_005252535 /// XM_005252536 /// XM_006717471 /// XM_006717472 /// XM_006717473 /// XM_006717474 /// XM_006717475 /// XM_006717476 /// XM_006717477 /// XM_006717478 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0003383 // apical constriction // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008356 // asymmetric cell division // traceable author statement /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0044319 // wound healing, spreading of cells // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060341 // regulation of cellular localization // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0033269 // internode region of axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from sequence or structural similarity 221527_s_at AF196185 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF196185.1 /DEF=Homo sapiens atypical PKC isotype-specific interacting protein long variant mRNA, complete cds. /FEA=mRNA /PROD=atypical PKC isotype-specific interactingprotein long variant /DB_XREF=gi:13491609 /UG=Hs.72249 three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect) /FL=gb:AF196185.1 AF196185 par-3 family cell polarity regulator PARD3 56288 NM_001184785 /// NM_001184786 /// NM_001184787 /// NM_001184788 /// NM_001184789 /// NM_001184790 /// NM_001184791 /// NM_001184792 /// NM_001184793 /// NM_001184794 /// NM_019619 /// XM_005252528 /// XM_005252530 /// XM_005252531 /// XM_005252532 /// XM_005252534 /// XM_005252535 /// XM_005252536 /// XM_006717471 /// XM_006717472 /// XM_006717473 /// XM_006717474 /// XM_006717475 /// XM_006717476 /// XM_006717477 /// XM_006717478 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0003383 // apical constriction // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006612 // protein targeting to membrane // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008356 // asymmetric cell division // traceable author statement /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032970 // regulation of actin filament-based process // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0044319 // wound healing, spreading of cells // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from electronic annotation /// 0060341 // regulation of cellular localization // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from sequence or structural similarity /// 0070830 // tight junction assembly // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005938 // cell cortex // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0033269 // internode region of axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from sequence or structural similarity 221528_s_at BC000143 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000143.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ11656, clone MGC:5247, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ11656 /DB_XREF=gi:12652782 /UG=Hs.96560 hypothetical protein FLJ11656 /FL=gb:BC000143.1 BC000143 engulfment and cell motility 2 ELMO2 63916 NM_022086 /// NM_133171 /// NM_182764 /// XM_005260496 /// XM_005260497 /// XM_005260498 /// XM_005260499 /// XM_005260500 /// XM_005260501 /// XM_005260502 /// XM_006723854 /// XM_006723855 0006909 // phagocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 221529_s_at AF326591 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF326591.1 /DEF=Homo sapiens fenestrated-endothelial linked structure protein (FELS) mRNA, complete cds. /FEA=mRNA /GEN=FELS /PROD=fenestrated-endothelial linked structureprotein /DB_XREF=gi:12963352 /UG=Hs.107125 Homo sapiens PV1 protein (PLVAP) mRNA, complete cds /FL=gb:AF326591.1 gb:AF348827.1 AF326591 plasmalemma vesicle associated protein PLVAP 83483 NM_031310 0000165 // MAPK cascade // inferred from direct assay /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0070528 // protein kinase C signaling // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 221530_s_at BE857425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE857425 /FEA=EST /DB_XREF=gi:10371439 /DB_XREF=est:7f97a11.x1 /CLONE=IMAGE:3304892 /UG=Hs.33829 bHLH protein DEC2 /FL=gb:AB044088.1 BE857425 basic helix-loop-helix family, member e41 BHLHE41 79365 NM_030762 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010832 // negative regulation of myotube differentiation // inferred from sequence or structural similarity /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from sequence or structural similarity /// 0030154 // cell differentiation // non-traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from sequence or structural similarity /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from sequence or structural similarity /// 0043426 // MRF binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 221531_at AF309553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF309553.1 /DEF=Homo sapiens meiotic recombination protein REC14 mRNA, complete cds. /FEA=mRNA /PROD=meiotic recombination protein REC14 /DB_XREF=gi:11139241 /UG=Hs.296242 recombination protein REC14 /FL=gb:AF309553.1 gb:NM_025234.1 AF309553 WD repeat domain 61 WDR61 80349 NM_025234 /// XM_005254698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 2001162 // positive regulation of histone H3-K79 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221532_s_at AF309553 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF309553.1 /DEF=Homo sapiens meiotic recombination protein REC14 mRNA, complete cds. /FEA=mRNA /PROD=meiotic recombination protein REC14 /DB_XREF=gi:11139241 /UG=Hs.296242 recombination protein REC14 /FL=gb:AF309553.1 gb:NM_025234.1 AF309553 WD repeat domain 61 WDR61 80349 NM_025234 /// XM_005254698 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 2001162 // positive regulation of histone H3-K79 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221533_at AF250321 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF250321.1 /DEF=Homo sapiens DC16 mRNA, complete cds. /FEA=mRNA /PROD=DC16 /DB_XREF=gi:12005679 /UG=Hs.5243 hypothetical protein, estradiol-induced /FL=gb:AF250321.1 gb:AF201944.1 AF250321 family with sequence similarity 162, member A FAM162A 26355 NM_014367 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006927 // transformed cell apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221534_at AF073483 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF073483.1 /DEF=Homo sapiens p5326 mRNA, complete cds. /FEA=mRNA /PROD=p5326 /DB_XREF=gi:12002057 /UG=Hs.93678 Homo sapiens, clone IMAGE:3640823, mRNA, partial cds /FL=gb:AF073483.1 AF073483 chromosome 11 open reading frame 68 C11orf68 83638 NM_001135635 /// NM_031450 0044822 // poly(A) RNA binding // inferred from direct assay 221535_at AL136897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136897.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E248 (from clone DKFZp434E248); complete cds. /FEA=mRNA /GEN=DKFZp434E248 /PROD=hypothetical protein /DB_XREF=gi:12053290 /UG=Hs.301724 Homo sapiens mRNA; cDNA DKFZp434E248 (from clone DKFZp434E248); complete cds /FL=gb:AL136897.1 AL136897 large 60S subunit nuclear export GTPase 1 LSG1 55341 NM_018385 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042254 // ribosome biogenesis // not recorded /// 0051168 // nuclear export // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 221536_s_at AL136897 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136897.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E248 (from clone DKFZp434E248); complete cds. /FEA=mRNA /GEN=DKFZp434E248 /PROD=hypothetical protein /DB_XREF=gi:12053290 /UG=Hs.301724 Homo sapiens mRNA; cDNA DKFZp434E248 (from clone DKFZp434E248); complete cds /FL=gb:AL136897.1 AL136897 large 60S subunit nuclear export GTPase 1 LSG1 55341 NM_018385 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042254 // ribosome biogenesis // not recorded /// 0051168 // nuclear export // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 221537_at T16388 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T16388 /FEA=EST /DB_XREF=gi:518550 /DB_XREF=est:NIB1234 /UG=Hs.322844 plexin A1 /FL=gb:AL136663.1 T16388 plexin A1 PLXNA1 5361 NM_032242 /// XM_006713663 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // traceable author statement 221538_s_at AL136663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136663.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564A176 (from clone DKFZp564A176); complete cds. /FEA=mRNA /GEN=DKFZp564A176 /PROD=hypothetical protein /DB_XREF=gi:12052849 /UG=Hs.322844 plexin A1 /FL=gb:AL136663.1 AL136663 plexin A1 PLXNA1 5361 NM_032242 /// XM_006713663 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0014910 // regulation of smooth muscle cell migration // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // traceable author statement 221539_at AB044548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB044548.1 /DEF=Homo sapiens POKcl.6 mRNA for eukaryotic translation initiation factor 4E binding protein 1, complete cds. /FEA=mRNA /GEN=POKcl.6 /PROD=eukaryotic translation initiation factor 4Ebinding protein 1 /DB_XREF=gi:11527778 /UG=Hs.71819 eukaryotic translation initiation factor 4E binding protein 1 /FL=gb:AB044548.1 gb:BC004459.1 gb:NM_004095.1 gb:L36055.1 AB044548 eukaryotic translation initiation factor 4E binding protein 1 EIF4EBP1 1978 NM_004095 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008190 // eukaryotic initiation factor 4E binding // inferred from electronic annotation /// 0030371 // translation repressor activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from electronic annotation 221540_x_at AF078847 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF078847.1 /DEF=Homo sapiens basic transcription factor 2 mRNA, complete cds. /FEA=mRNA /PROD=basic transcription factor 2 /DB_XREF=gi:5531808 /UG=Hs.191356 general transcription factor IIH, polypeptide 2 (44kD subunit) /FL=gb:AF078847.1 gb:NM_001515.1 AF078847 general transcription factor IIH, polypeptide 2, 44kDa /// general transcription factor IIH, polypeptide 2B (pseudogene) /// GTF2H2 family member C /// GTF2H2 family member C, copy 2 GTF2H2 /// GTF2H2B /// GTF2H2C /// GTF2H2C_2 2966 /// 653238 /// 728340 /// 730394 NM_001042490 /// NM_001098728 /// NM_001098729 /// NM_001515 /// NR_033417 /// XM_005248484 /// XM_005248489 /// XM_005248588 /// XM_005248590 /// XM_005248591 /// XM_005248592 /// XM_005248593 /// XM_005248594 /// XM_005276784 /// XM_005276786 /// XM_005276787 /// XM_005276788 /// XM_005276789 /// XM_005276796 /// XM_005276797 /// XM_005276798 /// XM_006714594 /// XM_006714595 /// XM_006714596 /// XM_006714688 /// XM_006714689 /// XM_006725448 /// XM_006725449 /// XM_006725450 /// XM_006725451 /// XM_006725452 /// XM_006726217 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006412 // translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 221541_at AL136861 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136861.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B044 (from clone DKFZp434B044); complete cds. /FEA=mRNA /GEN=DKFZp434B044 /PROD=hypothetical protein /DB_XREF=gi:12053226 /UG=Hs.262958 Homo sapiens mRNA; cDNA DKFZp434B044 (from clone DKFZp434B044); complete cds /FL=gb:AL136861.1 AL136861 cysteine-rich secretory protein LCCL domain containing 2 CRISPLD2 83716 NM_031476 /// XM_005256190 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 221542_s_at T90773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:T90773 /FEA=EST /DB_XREF=gi:722686 /DB_XREF=est:yd48d02.s1 /CLONE=IMAGE:111459 /UG=Hs.125849 chromosome 8 open reading frame 2 /FL=gb:AL442077.1 gb:NM_007175.1 T90773 ER lipid raft associated 2 ERLIN2 11160 NM_001003790 /// NM_001003791 /// NM_007175 /// XM_005273391 /// XM_005273392 /// XM_005273393 /// XM_006716280 0008219 // cell death // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221543_s_at AL442077 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL442077.1 /DEF=Homo sapiens mRNA; cDNA DKFZp667H242 (from clone DKFZp667H242); complete cds. /FEA=mRNA /GEN=DKFZp667H242 /PROD=hypothetical protein /DB_XREF=gi:10241715 /UG=Hs.125849 chromosome 8 open reading frame 2 /FL=gb:AL442077.1 gb:NM_007175.1 AL442077 ER lipid raft associated 2 ERLIN2 11160 NM_001003790 /// NM_001003791 /// NM_007175 /// XM_005273391 /// XM_005273392 /// XM_005273393 /// XM_006716280 0008219 // cell death // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221544_s_at BG339606 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG339606 /FEA=EST /DB_XREF=gi:13146044 /DB_XREF=est:602437464F1 /CLONE=IMAGE:4555622 /UG=Hs.31659 thyroid hormone receptor-associated protein, 95-kD subunit /FL=gb:AF106934.1 BG339606 mediator complex subunit 16 MED16 10025 NM_005481 /// XM_006722600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from direct assay /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 221545_x_at AF106934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF106934.1 /DEF=Homo sapiens vitamin D receptor-interacting protein (DRIP92) mRNA, complete cds. /FEA=mRNA /GEN=DRIP92 /PROD=vitamin D receptor-interacting protein /DB_XREF=gi:4868007 /UG=Hs.31659 thyroid hormone receptor-associated protein, 95-kD subunit /FL=gb:AF106934.1 AF106934 mediator complex subunit 16 MED16 10025 NM_005481 /// XM_006722600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from direct assay /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 221546_at BC000794 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000794.1 /DEF=Homo sapiens, pre-mRNA splicing factor similar to S. cerevisiae Prp18, clone MGC:5075, mRNA, complete cds. /FEA=mRNA /PROD=pre-mRNA splicing factor similar to S.cerevisiae Prp18 /DB_XREF=gi:12653992 /UG=Hs.155244 pre-mRNA processing factor 18 /FL=gb:BC000794.1 gb:U51990.1 gb:NM_003675.1 BC000794 pre-mRNA processing factor 18 PRPF18 8559 NM_003675 /// XM_005252634 /// XM_005252636 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0019870 // potassium channel inhibitor activity // inferred from electronic annotation 221547_at BC000794 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000794.1 /DEF=Homo sapiens, pre-mRNA splicing factor similar to S. cerevisiae Prp18, clone MGC:5075, mRNA, complete cds. /FEA=mRNA /PROD=pre-mRNA splicing factor similar to S.cerevisiae Prp18 /DB_XREF=gi:12653992 /UG=Hs.155244 pre-mRNA processing factor 18 /FL=gb:BC000794.1 gb:U51990.1 gb:NM_003675.1 BC000794 pre-mRNA processing factor 18 PRPF18 8559 NM_003675 /// XM_005252634 /// XM_005252636 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0019870 // potassium channel inhibitor activity // inferred from electronic annotation 221548_s_at AY024365 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY024365.1 /DEF=Homo sapiens integrin-linked kinase-associated serinethreonine phosphatase 2C mRNA, complete cds. /FEA=mRNA /PROD=integrin-linked kinase-associatedserinethreonine phosphatase 2C /DB_XREF=gi:13432041 /UG=Hs.92033 integrin-linked kinase-associated serinethreonine phosphatase 2C /FL=gb:AL136850.1 gb:AY024365.1 AY024365 integrin-linked kinase-associated serine/threonine phosphatase ILKAP 80895 NM_030768 /// NM_176799 /// XM_005246106 /// XM_006712784 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033262 // regulation of nuclear cell cycle DNA replication // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221549_at AF337808 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF337808.1 /DEF=Homo sapiens glutamate rich WD repeat protein (GRWD) mRNA, complete cds. /FEA=mRNA /GEN=GRWD /PROD=glutamate rich WD repeat protein /DB_XREF=gi:13274610 /UG=Hs.218842 Homo sapiens glutamate rich WD repeat protein (GRWD) mRNA, complete cds /FL=gb:BC002440.1 gb:AF337808.1 AF337808 glutamate-rich WD repeat containing 1 GRWD1 83743 NM_031485 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221550_at BC002382 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002382.1 /DEF=Homo sapiens, COX15 (yeast) homolog, cytochrome c oxidase assembly protein, clone MGC:8634, mRNA, complete cds. /FEA=mRNA /PROD=COX15 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:12803156 /UG=Hs.226581 COX15 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:BC002382.1 gb:AF026850.1 BC002382 cytochrome c oxidase assembly homolog 15 (yeast) COX15 1355 NM_004376 /// NM_078470 /// XM_005269539 /// XM_006717633 /// XM_006717634 0006123 // mitochondrial electron transport, cytochrome c to oxygen // inferred by curator /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006784 // heme a biosynthetic process // inferred from electronic annotation /// 0006784 // heme a biosynthetic process // inferred from genetic interaction /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred by curator /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from genetic interaction /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004129 // cytochrome-c oxidase activity // inferred from genetic interaction /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation 221551_x_at AB035172 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035172.1 /DEF=Homo sapiens ST6GalNAc4 mRNA for N-acetylgalactosaminide alpha2,6-sialyltransferase, complete cds. /FEA=mRNA /GEN=ST6GalNAc4 /PROD=N-acetylgalactosaminidealpha2,6-sialyltransferase /DB_XREF=gi:6468226 /UG=Hs.3972 NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2, 6-sialyltransferase alpha2,6-sialyltransferase /FL=gb:AB035172.1 AB035172 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6GALNAC4 27090 NM_014403 /// NM_175039 /// NM_175040 /// XM_005251922 0006486 // protein glycosylation // inferred from electronic annotation /// 0006664 // glycolipid metabolic process // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047290 // (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity // inferred from electronic annotation 221552_at BC001698 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001698.1 /DEF=Homo sapiens, Similar to lipase protein, clone MGC:2843, mRNA, complete cds. /FEA=mRNA /PROD=Similar to lipase protein /DB_XREF=gi:12804562 /UG=Hs.20220 lipase protein /FL=gb:NM_020676.1 gb:BC001698.1 BC001698 abhydrolase domain containing 6 ABHD6 57406 NM_020676 /// XM_005265334 /// XM_005265335 /// XM_005265336 0008152 // metabolic process // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 2000124 // regulation of endocannabinoid signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation 221553_at AL136636 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136636.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K142 (from clone DKFZp564K142); complete cds. /FEA=mRNA /GEN=DKFZp564K142 /PROD=hypothetical protein /DB_XREF=gi:12052797 /UG=Hs.323562 Homo sapiens mRNA; cDNA DKFZp564K142 (from clone DKFZp564K142); complete cds /FL=gb:AL136636.1 AL136636 magnesium transporter 1 MAGT1 84061 NM_032121 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype 221554_at AF308302 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF308302.1 /DEF=Homo sapiens serologically defined breast cancer antigen NY-BR-96 mRNA, complete cds. /FEA=mRNA /PROD=serologically defined breast cancer antigenNY-BR-96 /DB_XREF=gi:12060854 /UG=Hs.4789 Homo sapiens serologically defined breast cancer antigen NY-BR-96 mRNA, complete cds /FL=gb:AF308302.1 AF308302 STE20-related kinase adaptor alpha STRADA 92335 NM_001003786 /// NM_001003787 /// NM_001003788 /// NM_001165969 /// NM_001165970 /// NM_153335 /// XM_005257797 /// XM_005257798 /// XM_005257799 /// XM_005257800 /// XM_005257801 /// XM_005257803 /// XR_243687 /// XR_243688 0006468 // protein phosphorylation // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0032147 // activation of protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay 221555_x_at AU145941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145941 /FEA=EST /DB_XREF=gi:11007462 /DB_XREF=est:AU145941 /CLONE=HEMBA1006337 /UG=Hs.22116 CDC14 (cell division cycle 14, S. cerevisiae) homolog B /FL=gb:AF064104.1 AU145941 cell division cycle 14B CDC14B 8555 NM_001077181 /// NM_003671 /// NM_033331 /// NM_033332 /// XM_005252286 /// XM_005252287 /// XM_005252288 /// XR_242602 /// XR_242603 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 221556_at BF792631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF792631 /FEA=EST /DB_XREF=gi:12097685 /DB_XREF=est:602253794F1 /CLONE=IMAGE:4346254 /UG=Hs.22116 CDC14 (cell division cycle 14, S. cerevisiae) homolog B /FL=gb:AF064104.1 BF792631 cell division cycle 14B CDC14B 8555 NM_001077181 /// NM_003671 /// NM_033331 /// NM_033332 /// XM_005252286 /// XM_005252287 /// XM_005252288 /// XR_242602 /// XR_242603 0002576 // platelet degranulation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0051488 // activation of anaphase-promoting complex activity // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 221557_s_at AI762816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI762816 /FEA=EST /DB_XREF=gi:5178483 /DB_XREF=est:wi04e08.x1 /CLONE=IMAGE:2389286 /UG=Hs.44865 lymphoid enhancer binding factor-1 /FL=gb:AF198532.1 gb:NM_016269.1 gb:AF288571.1 AI762816 lymphoid enhancer-binding factor 1 LEF1 51176 NM_001130713 /// NM_001130714 /// NM_001166119 /// NM_016269 /// XM_005263046 /// XM_005263047 /// XM_005263048 /// XM_006714233 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001755 // neural crest cell migration // not recorded /// 0001756 // somitogenesis // not recorded /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016202 // regulation of striated muscle tissue development // not recorded /// 0021542 // dentate gyrus development // not recorded /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // not recorded /// 0021861 // forebrain radial glial cell differentiation // not recorded /// 0021873 // forebrain neuroblast division // not recorded /// 0021879 // forebrain neuron differentiation // not recorded /// 0021943 // formation of radial glial scaffolds // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030223 // neutrophil differentiation // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // not recorded /// 0030854 // positive regulation of granulocyte differentiation // inferred from direct assay /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030879 // mammary gland development // not recorded /// 0032696 // negative regulation of interleukin-13 production // inferred from direct assay /// 0032713 // negative regulation of interleukin-4 production // inferred from direct assay /// 0032714 // negative regulation of interleukin-5 production // inferred from direct assay /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042100 // B cell proliferation // not recorded /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from mutant phenotype /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0045063 // T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046632 // alpha-beta T cell differentiation // not recorded /// 0048069 // eye pigmentation // not recorded /// 0048341 // paraxial mesoderm formation // not recorded /// 0048468 // cell development // inferred from electronic annotation /// 0048747 // muscle fiber development // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060325 // face morphogenesis // not recorded /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060561 // apoptotic process involved in morphogenesis // not recorded /// 0060710 // chorio-allantoic fusion // not recorded /// 0061153 // trachea gland development // not recorded /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from mutant phenotype /// 0071866 // negative regulation of apoptotic process in bone marrow // inferred from mutant phenotype /// 0071895 // odontoblast differentiation // not recorded /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 0090068 // positive regulation of cell cycle process // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0035326 // enhancer binding // inferred from direct assay /// 0042393 // histone binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 221558_s_at AF288571 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288571.1 /DEF=Homo sapiens lymphoid enhancer factor-1 (LEF1) mRNA, complete cds. /FEA=mRNA /GEN=LEF1 /PROD=lymphoid enhancer factor-1 /DB_XREF=gi:9858157 /UG=Hs.44865 lymphoid enhancer binding factor-1 /FL=gb:AF198532.1 gb:NM_016269.1 gb:AF288571.1 AF288571 lymphoid enhancer-binding factor 1 LEF1 51176 NM_001130713 /// NM_001130714 /// NM_001166119 /// NM_016269 /// XM_005263046 /// XM_005263047 /// XM_005263048 /// XM_006714233 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001755 // neural crest cell migration // not recorded /// 0001756 // somitogenesis // not recorded /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001944 // vasculature development // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016202 // regulation of striated muscle tissue development // not recorded /// 0021542 // dentate gyrus development // not recorded /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021854 // hypothalamus development // not recorded /// 0021861 // forebrain radial glial cell differentiation // not recorded /// 0021873 // forebrain neuroblast division // not recorded /// 0021879 // forebrain neuron differentiation // not recorded /// 0021943 // formation of radial glial scaffolds // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030223 // neutrophil differentiation // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // not recorded /// 0030854 // positive regulation of granulocyte differentiation // inferred from direct assay /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030879 // mammary gland development // not recorded /// 0032696 // negative regulation of interleukin-13 production // inferred from direct assay /// 0032713 // negative regulation of interleukin-4 production // inferred from direct assay /// 0032714 // negative regulation of interleukin-5 production // inferred from direct assay /// 0033153 // T cell receptor V(D)J recombination // inferred from electronic annotation /// 0042100 // B cell proliferation // not recorded /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from mutant phenotype /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0045063 // T-helper 1 cell differentiation // inferred from sequence or structural similarity /// 0045843 // negative regulation of striated muscle tissue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046632 // alpha-beta T cell differentiation // not recorded /// 0048069 // eye pigmentation // not recorded /// 0048341 // paraxial mesoderm formation // not recorded /// 0048468 // cell development // inferred from electronic annotation /// 0048747 // muscle fiber development // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060033 // anatomical structure regression // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060325 // face morphogenesis // not recorded /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060561 // apoptotic process involved in morphogenesis // not recorded /// 0060710 // chorio-allantoic fusion // not recorded /// 0061153 // trachea gland development // not recorded /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from direct assay /// 0071864 // positive regulation of cell proliferation in bone marrow // inferred from mutant phenotype /// 0071866 // negative regulation of apoptotic process in bone marrow // inferred from mutant phenotype /// 0071895 // odontoblast differentiation // not recorded /// 0071899 // negative regulation of estrogen receptor binding // inferred from direct assay /// 0090068 // positive regulation of cell cycle process // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0035326 // enhancer binding // inferred from direct assay /// 0042393 // histone binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 221559_s_at BC000229 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000229.1 /DEF=Homo sapiens, clone MGC:2488, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2488) /DB_XREF=gi:12652942 /UG=Hs.267194 hypothetical protein MGC2488 /FL=gb:BC000229.1 BC000229 MIS12 kinetochore complex component MIS12 79003 NM_001258217 /// NM_001258218 /// NM_001258219 /// NM_001258220 /// NM_024039 /// XM_005256797 /// XM_005256798 /// XM_006721575 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from direct assay 0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 221560_at AB049127 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049127.1 /DEF=Homo sapiens MARKL1 mRNA for MAPmicrotubule affinity-regulating kinase like 1, complete cds. /FEA=mRNA /GEN=MARKL1 /PROD=MAPmicrotubule affinity-regulating kinase like1 /DB_XREF=gi:13366083 /UG=Hs.8312 Homo sapiens MARKL1 mRNA for MAPmicrotubule affinity-regulating kinase like 1, complete cds /FL=gb:AB049127.1 AB049127 MAP/microtubule affinity-regulating kinase 4 MARK4 57787 NM_001199867 /// NM_031417 /// XM_006723307 0000082 // G1/S transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001578 // microtubule bundle formation // inferred from expression pattern /// 0006468 // protein phosphorylation // traceable author statement /// 0007399 // nervous system development // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // non-traceable author statement 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0008017 // microtubule binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043015 // gamma-tubulin binding // inferred from direct assay /// 0043130 // ubiquitin binding // non-traceable author statement /// 0050321 // tau-protein kinase activity // inferred from direct assay 221561_at L21934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L21934.2 /DEF=Homo sapiens acyl-coenzyme A: cholesterol acyltransferase mRNA, complete cds. /FEA=mRNA /PROD=acyl-coenzyme A: cholesterol acyltransferase /DB_XREF=gi:4878021 /UG=Hs.14553 sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 /FL=gb:NM_003101.1 gb:L21934.2 L21934 sterol O-acyltransferase 1 SOAT1 6646 NM_001252511 /// NM_001252512 /// NM_003101 /// NR_045530 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010742 // macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010742 // macrophage derived foam cell differentiation // non-traceable author statement /// 0010878 // cholesterol storage // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034435 // cholesterol esterification // inferred from direct assay /// 0034435 // cholesterol esterification // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // traceable author statement /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0004772 // sterol O-acyltransferase activity // inferred from direct assay /// 0004772 // sterol O-acyltransferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0034736 // cholesterol O-acyltransferase activity // inferred from direct assay /// 0034736 // cholesterol O-acyltransferase activity // inferred from mutant phenotype 221562_s_at AF083108 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF083108.2 /DEF=Homo sapiens sirtuin type 3 (SIRT3) mRNA, complete cds. /FEA=mRNA /GEN=SIRT3 /PROD=sirtuin type 3 /DB_XREF=gi:13259626 /UG=Hs.19306 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3 /FL=gb:BC001042.1 gb:AF083108.2 gb:NM_012239.3 AF083108 sirtuin 3 SIRT3 23410 NM_001017524 /// NM_012239 /// XM_005252835 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 221563_at N36770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N36770 /FEA=EST /DB_XREF=gi:1157912 /DB_XREF=est:yy34c02.s1 /CLONE=IMAGE:273122 /UG=Hs.177534 dual specificity phosphatase 10 /FL=gb:NM_007207.2 gb:AB026436.1 gb:AF179212.1 N36770 dual specificity phosphatase 10 DUSP10 11221 NM_007207 /// NM_144728 /// NM_144729 /// NR_111939 /// NR_111940 0000188 // inactivation of MAPK activity // inferred from direct assay /// 0002819 // regulation of adaptive immune response // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // not recorded /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // not recorded /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from direct assay 221564_at AL570294 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL570294 /FEA=EST /DB_XREF=gi:12926461 /DB_XREF=est:AL570294 /CLONE=CS0DI004YN01 (3 prime) /UG=Hs.235887 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 /FL=gb:AF059319.1 AL570294 protein arginine methyltransferase 2 PRMT2 3275 NM_001242864 /// NM_001242865 /// NM_001242866 /// NM_001286676 /// NM_001286677 /// NM_001286678 /// NM_001535 /// NM_206962 /// XM_005261111 /// XM_006723998 /// XM_006723999 /// XM_006724000 0006479 // protein methylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048588 // developmental cell growth // inferred from sequence or structural similarity /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035189 // Rb-E2F complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0008469 // histone-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0033142 // progesterone receptor binding // inferred from physical interaction /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 221565_s_at BC000039 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000039.1 /DEF=Homo sapiens, Similar to hypothetical protein, clone MGC:1824, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein /DB_XREF=gi:12652592 /UG=Hs.241545 hypothetical protein /FL=gb:BC000039.1 gb:NM_015916.1 BC000039 calcium homeostasis modulator 2 CALHM2 51063 NM_015916 /// NR_024552 /// NR_046344 /// XM_006717877 /// XM_006717878 /// XM_006717879 /// XM_006717880 /// XM_006717881 /// XM_006717882 /// XM_006717883 /// XM_006717884 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221566_s_at AF043244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF043244.1 /DEF=Homo sapiens apoptosis repressor ARC (ARC) mRNA, complete cds. /FEA=mRNA /GEN=ARC /PROD=apoptosis repressor ARC /DB_XREF=gi:3126906 /UG=Hs.278439 nucleolar protein 3 (apoptosis repressor with CARD domain) /FL=gb:AF043244.1 gb:AF064599.1 gb:AF064600.1 gb:NM_003946.1 AF043244 nucleolar protein 3 (apoptosis repressor with CARD domain) NOL3 8996 NM_001185057 /// NM_001185058 /// NM_001276307 /// NM_001276309 /// NM_001276311 /// NM_001276312 /// NM_001276319 /// NM_003946 /// XM_005256217 /// XM_005256219 /// XM_006721322 /// XM_006721323 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016528 // sarcoplasm // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 221567_at AF064599 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF064599.1 /DEF=Homo sapiens nucleolar protein Nop30 (NOP) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=NOP /PROD=nucleolar protein Nop30 /DB_XREF=gi:3172418 /UG=Hs.278439 nucleolar protein 3 (apoptosis repressor with CARD domain) /FL=gb:AF043244.1 gb:AF064599.1 gb:AF064600.1 gb:NM_003946.1 AF064599 nucleolar protein 3 (apoptosis repressor with CARD domain) NOL3 8996 NM_001185057 /// NM_001185058 /// NM_001276307 /// NM_001276309 /// NM_001276311 /// NM_001276312 /// NM_001276319 /// NM_003946 /// XM_005256217 /// XM_005256219 /// XM_006721322 /// XM_006721323 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016528 // sarcoplasm // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 221568_s_at AF090900 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF090900.1 /DEF=Homo sapiens clone HQ0189 PRO0189 mRNA, complete cds. /FEA=mRNA /PROD=PRO0189 /DB_XREF=gi:6690176 /UG=Hs.91393 Homo sapiens cDNA: FLJ21887 fis, clone HEP03135, highly similar to AF090900 Homo sapiens clone HQ0189 PRO0189 mRNA /FL=gb:AF090900.1 AF090900 lin-7 homolog C (C. elegans) LIN7C 55327 NM_018362 0002011 // morphogenesis of an epithelial sheet // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0097016 // L27 domain binding // inferred from direct assay 221569_at AL136797 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136797.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434N031 (from clone DKFZp434N031); complete cds. /FEA=mRNA /GEN=DKFZp434N031 /PROD=hypothetical protein /DB_XREF=gi:12053106 /UG=Hs.273294 hypothetical protein FLJ20069 /FL=gb:AL136797.1 AL136797 Abelson helper integration site 1 AHI1 54806 NM_001134830 /// NM_001134831 /// NM_001134832 /// NM_017651 /// XM_005267039 /// XM_006715507 /// XR_427973 0001738 // morphogenesis of a polarized epithelium // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002092 // positive regulation of receptor internalization // inferred from sequence or structural similarity /// 0006903 // vesicle targeting // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030862 // positive regulation of polarized epithelial cell differentiation // inferred from sequence or structural similarity /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from sequence or structural similarity /// 0035844 // cloaca development // inferred from sequence or structural similarity /// 0035845 // photoreceptor cell outer segment organization // inferred from sequence or structural similarity /// 0039008 // pronephric nephron tubule morphogenesis // inferred from sequence or structural similarity /// 0039023 // pronephric duct morphogenesis // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050795 // regulation of behavior // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0065001 // specification of axis polarity // inferred from sequence or structural similarity /// 0070121 // Kupffer's vesicle development // inferred from sequence or structural similarity /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071599 // otic vesicle development // inferred from sequence or structural similarity 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221570_s_at AF201938 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF201938.1 /DEF=Homo sapiens DC3 (DC3) mRNA, complete cds. /FEA=mRNA /GEN=DC3 /PROD=DC3 /DB_XREF=gi:9295179 /UG=Hs.273063 HSPC133 protein /FL=gb:AF201938.1 AF201938 methyltransferase like 5 METTL5 29081 NM_001293186 /// NM_001293187 /// NM_014168 /// XM_005246478 /// XM_005246479 /// XM_006712458 0001510 // RNA methylation // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009452 // 7-methylguanosine RNA capping // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221571_at AI721219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI721219 /FEA=EST /DB_XREF=gi:5038475 /DB_XREF=est:as68b11.x1 /CLONE=IMAGE:2333853 /UG=Hs.297660 TNF receptor-associated factor 3 /FL=gb:U15637.1 gb:U19260.1 AI721219 TNF receptor-associated factor 3 TRAF3 7187 NM_001199427 /// NM_003300 /// NM_145725 /// NM_145726 /// XM_006720244 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030162 // regulation of proteolysis // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032648 // regulation of interferon-beta production // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050688 // regulation of defense response to virus // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221572_s_at AF288410 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF288410.1 /DEF=Homo sapiens solute carrier family 26 member 6 (SLC26A6) mRNA, complete cds. /FEA=mRNA /GEN=SLC26A6 /PROD=solute carrier family 26 member 6 /DB_XREF=gi:13344998 /UG=Hs.298476 solute carrier family 26, member 6 /FL=gb:AF288410.1 AF288410 microRNA 6824 /// solute carrier family 26 (anion exchanger), member 6 MIR6824 /// SLC26A6 65010 /// 102465495 NM_001040454 /// NM_001281732 /// NM_001281733 /// NM_022911 /// NM_134263 /// NM_134426 /// NR_106882 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0006821 // chloride transport // inferred from mutant phenotype /// 0008272 // sulfate transport // inferred from mutant phenotype /// 0008272 // sulfate transport // inferred from sequence or structural similarity /// 0015701 // bicarbonate transport // inferred from direct assay /// 0015701 // bicarbonate transport // inferred from mutant phenotype /// 0015724 // formate transport // inferred from sequence or structural similarity /// 0015797 // mannitol transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from mutant phenotype /// 0019532 // oxalate transport // inferred from sequence or structural similarity /// 0030321 // transepithelial chloride transport // inferred from mutant phenotype /// 0030321 // transepithelial chloride transport // inferred from sequence or structural similarity /// 0038166 // angiotensin-activated signaling pathway // inferred from direct assay /// 0042045 // epithelial fluid transport // inferred from sequence or structural similarity /// 0046724 // oxalic acid secretion // inferred from sequence or structural similarity /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0050892 // intestinal absorption // inferred from sequence or structural similarity /// 0051453 // regulation of intracellular pH // inferred from direct assay /// 0051453 // regulation of intracellular pH // inferred from mutant phenotype /// 0051454 // intracellular pH elevation // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070528 // protein kinase C signaling // inferred from direct assay /// 0070633 // transepithelial transport // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071332 // cellular response to fructose stimulus // inferred from sequence or structural similarity /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1902358 // sulfate transmembrane transport // inferred from direct assay /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from sequence or structural similarity /// 2001150 // positive regulation of dipeptide transmembrane transport // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from direct assay /// 0031988 // membrane-bounded vesicle // inferred from sequence or structural similarity /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0097225 // sperm midpiece // inferred from sequence or structural similarity 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015106 // bicarbonate transmembrane transporter activity // inferred from direct assay /// 0015106 // bicarbonate transmembrane transporter activity // inferred from mutant phenotype /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015108 // chloride transmembrane transporter activity // inferred from direct assay /// 0015108 // chloride transmembrane transporter activity // inferred from mutant phenotype /// 0015108 // chloride transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from direct assay /// 0015116 // sulfate transmembrane transporter activity // inferred from mutant phenotype /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from direct assay /// 0015301 // anion:anion antiporter activity // inferred from mutant phenotype /// 0015301 // anion:anion antiporter activity // inferred from sequence or structural similarity /// 0015499 // formate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015562 // efflux transmembrane transporter activity // inferred from sequence or structural similarity /// 0015659 // formate uptake transmembrane transporter activity // inferred from sequence or structural similarity /// 0015660 // formate efflux transmembrane transporter activity // inferred from sequence or structural similarity /// 0019531 // oxalate transmembrane transporter activity // inferred from mutant phenotype /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity 221573_at BC000769 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000769.1 /DEF=Homo sapiens, clone MGC:2821, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2821) /DB_XREF=gi:12653950 /UG=Hs.59594 hypothetical protein MGC2821 /FL=gb:BC000769.1 gb:BC001845.1 gb:NM_024054.1 BC000769 chromosome 7 open reading frame 25 /// proteasome (prosome, macropain) subunit, alpha type, 2 C7orf25 /// PSMA2 5683 /// 79020 NM_001099858 /// NM_002787 /// NM_024054 /// XM_005249844 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221575_at BC000586 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000586.1 /DEF=Homo sapiens, putative selenocysteine lyase, clone MGC:3039, mRNA, complete cds. /FEA=mRNA /PROD=putative selenocysteine lyase /DB_XREF=gi:12653616 /UG=Hs.285306 putative selenocysteine lyase /FL=gb:BC000586.1 BC000586 selenocysteine lyase SCLY 51540 NM_016510 0006520 // cellular amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009000 // selenocysteine lyase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019788 // NEDD8 ligase activity // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 221576_at BC000529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000529.1 /DEF=Homo sapiens, prostate differentiation factor, clone MGC:8645, mRNA, complete cds. /FEA=mRNA /PROD=prostate differentiation factor /DB_XREF=gi:12653514 /UG=Hs.296638 prostate differentiation factor /FL=gb:BC000529.1 gb:AB000584.1 gb:U88323.1 gb:AF003934.1 gb:AF019770.1 gb:NM_004864.1 BC000529 growth differentiation factor 15 GDF15 9518 NM_004864 0007165 // signal transduction // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221577_x_at AF003934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF003934.1 /DEF=Homo sapiens prostate differentiation factor mRNA, complete cds. /FEA=mRNA /PROD=prostate differentiation factor /DB_XREF=gi:2290971 /UG=Hs.296638 prostate differentiation factor /FL=gb:BC000529.1 gb:AB000584.1 gb:U88323.1 gb:AF003934.1 gb:AF019770.1 gb:NM_004864.1 AF003934 growth differentiation factor 15 GDF15 9518 NM_004864 0007165 // signal transduction // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221578_at AF260335 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF260335.1 /DEF=Homo sapiens AD037 mRNA, complete cds. /FEA=mRNA /PROD=AD037 /DB_XREF=gi:12005907 /UG=Hs.318715 Homo sapiens AD037 mRNA, complete cds /FL=gb:AF260335.1 AF260335 Ras association (RalGDS/AF-6) domain family member 4 RASSF4 83937 NM_032023 /// NM_178145 /// XM_005271833 /// XM_005271835 /// XM_006718013 /// XM_006718014 /// XM_006718015 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221579_s_at AF062530 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF062530.1 /DEF=Homo sapiens clone 469920 diphosphoinositol polyphosphate phosphohydrolase mRNA, complete cds. /FEA=mRNA /PROD=diphosphoinositol polyphosphatephosphohydrolase /DB_XREF=gi:3978225 /UG=Hs.4815 nudix (nucleoside diphosphate linked moiety X)-type motif 3 /FL=gb:AF062529.1 gb:AF062530.1 gb:NM_006703.1 AF062530 nudix (nucleoside diphosphate linked moiety X)-type motif 3 /// RPS10-NUDT3 readthrough NUDT3 /// RPS10-NUDT3 11165 /// 100529239 NM_001202470 /// NM_006703 0007267 // cell-cell signaling // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation 221580_s_at BC001972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001972.1 /DEF=Homo sapiens, clone MGC:5306, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5306) /DB_XREF=gi:12805036 /UG=Hs.301732 hypothetical protein MGC5306 /FL=gb:BC001972.1 BC001972 microRNA 1304 /// small nucleolar RNA, H/ACA box 1 /// small nucleolar RNA, H/ACA box 18 /// small nucleolar RNA, H/ACA box 32 /// small nucleolar RNA, H/ACA box 40 /// small nucleolar RNA, H/ACA box 8 /// small nucleolar RNA, C/D box 5 /// TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa MIR1304 /// SNORA1 /// SNORA18 /// SNORA32 /// SNORA40 /// SNORA8 /// SNORD5 /// TAF1D 79101 /// 654320 /// 677792 /// 677805 /// 677822 /// 692063 /// 692072 /// 100302240 NM_024116 /// NR_002920 /// NR_002959 /// NR_002973 /// NR_003026 /// NR_003032 /// NR_003033 /// NR_031639 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005668 // RNA polymerase transcription factor SL1 complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221581_s_at AF257135 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF257135.1 /DEF=Homo sapiens WBSCR15 protein (WBSCR15) mRNA, complete cds. /FEA=mRNA /GEN=WBSCR15 /PROD=WBSCR15 protein /DB_XREF=gi:9651998 /UG=Hs.56607 Williams-Beuren syndrome chromosome region 5 /FL=gb:NM_022040.1 gb:BC001609.1 gb:AF257135.1 AF257135 linker for activation of T cells family, member 2 LAT2 7462 NM_014146 /// NM_032463 /// NM_032464 /// XM_005250562 0002376 // immune system process // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042113 // B cell activation // inferred from direct assay /// 0042113 // B cell activation // traceable author statement /// 0043303 // mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from mutant phenotype 221582_at BC001193 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001193.1 /DEF=Homo sapiens, H2A histone family, member L, clone MGC:3165, mRNA, complete cds. /FEA=mRNA /PROD=H2A histone family, member L /DB_XREF=gi:12654706 /UG=Hs.28777 H2A histone family, member L /FL=gb:BC001193.1 BC001193 histone cluster 3, H2a HIST3H2A 92815 NM_033445 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // inferred from mutant phenotype /// 0070914 // UV-damage excision repair // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221583_s_at AI129381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI129381 /FEA=EST /DB_XREF=gi:3597895 /DB_XREF=est:qc34d02.x1 /CLONE=IMAGE:1711491 /UG=Hs.89463 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 /FL=gb:AF025999.1 gb:NM_002247.1 gb:AF118141.1 gb:U13913.1 gb:U11717.1 gb:U23767.1 gb:U11058.2 AI129381 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 KCNMA1 3778 NM_001014797 /// NM_001161352 /// NM_001161353 /// NM_001271518 /// NM_001271519 /// NM_001271520 /// NM_001271521 /// NM_001271522 /// NM_002247 /// XM_005269776 /// XM_005269778 /// XM_005269779 /// XM_005269780 /// XM_005269781 /// XM_005269785 /// XM_005269787 /// XM_005269789 /// XM_005269792 /// XM_005269795 /// XM_005269796 /// XM_005269797 /// XM_005269800 /// XM_005269801 /// XM_005269803 /// XM_005269804 /// XM_006717821 /// XM_006717822 /// XM_006717823 /// XM_006717824 /// XM_006717825 /// XM_006717826 /// XM_006717827 /// XM_006717828 /// XM_006717829 /// XM_006717830 0001666 // response to hypoxia // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0006970 // response to osmotic stress // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030007 // cellular potassium ion homeostasis // inferred from direct assay /// 0032344 // regulation of aldosterone metabolic process // inferred from electronic annotation /// 0034465 // response to carbon monoxide // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045794 // negative regulation of cell volume // inferred from direct assay /// 0046541 // saliva secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060073 // micturition // inferred from direct assay /// 0060082 // eye blink reflex // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from direct assay /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from direct assay /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from mutant phenotype 221584_s_at U11058 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U11058.2 /DEF=Homo sapiens large conductance calcium- and voltage-dependent potassium channel alpha subunit (MaxiK) mRNA, complete cds. /FEA=mRNA /GEN=MaxiK /PROD=large conductance calcium- and voltage-dependentpotassium channel alpha subunit /DB_XREF=gi:7914977 /UG=Hs.89463 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 /FL=gb:AF025999.1 gb:NM_002247.1 gb:AF118141.1 gb:U13913.1 gb:U11717.1 gb:U23767.1 gb:U11058.2 U11058 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 KCNMA1 3778 NM_001014797 /// NM_001161352 /// NM_001161353 /// NM_001271518 /// NM_001271519 /// NM_001271520 /// NM_001271521 /// NM_001271522 /// NM_002247 /// XM_005269776 /// XM_005269778 /// XM_005269779 /// XM_005269780 /// XM_005269781 /// XM_005269785 /// XM_005269787 /// XM_005269789 /// XM_005269792 /// XM_005269795 /// XM_005269796 /// XM_005269797 /// XM_005269800 /// XM_005269801 /// XM_005269803 /// XM_005269804 /// XM_006717821 /// XM_006717822 /// XM_006717823 /// XM_006717824 /// XM_006717825 /// XM_006717826 /// XM_006717827 /// XM_006717828 /// XM_006717829 /// XM_006717830 0001666 // response to hypoxia // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0006970 // response to osmotic stress // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030007 // cellular potassium ion homeostasis // inferred from direct assay /// 0032344 // regulation of aldosterone metabolic process // inferred from electronic annotation /// 0034465 // response to carbon monoxide // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from mutant phenotype /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045794 // negative regulation of cell volume // inferred from direct assay /// 0046541 // saliva secretion // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060073 // micturition // inferred from direct assay /// 0060082 // eye blink reflex // inferred from electronic annotation /// 0060083 // smooth muscle contraction involved in micturition // inferred from direct assay /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded /// 0071805 // potassium ion transmembrane transport // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0043195 // terminal bouton // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from direct assay /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from direct assay /// 0060072 // large conductance calcium-activated potassium channel activity // inferred from mutant phenotype 221585_at BC004504 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004504.1 /DEF=Homo sapiens, clone MGC:11138, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:11138) /DB_XREF=gi:13325399 /UG=Hs.90207 Homo sapiens, clone MGC:11138, mRNA, complete cds /FL=gb:BC004504.1 BC004504 calcium channel, voltage-dependent, gamma subunit 4 CACNG4 27092 NM_014405 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation 221586_s_at U15642 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:U15642.1 /DEF=Human transcription factor E2F-5 mRNA, complete cds. /FEA=mRNA /PROD=E2F-5 /DB_XREF=gi:758415 /UG=Hs.2331 E2F transcription factor 5, p130-binding /FL=gb:NM_001951.2 gb:U15642.1 gb:U31556.1 U15642 E2F transcription factor 5, p130-binding E2F5 1875 NM_001083588 /// NM_001083589 /// NM_001951 /// XM_006716434 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction 221587_s_at BC000890 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000890.1 /DEF=Homo sapiens, hypothetical protein FLJ20640, clone MGC:4953, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20640 /DB_XREF=gi:12654144 /UG=Hs.25489 hypothetical protein FLJ20640 /FL=gb:BC000890.1 BC000890 chromosome 19 open reading frame 24 C19orf24 55009 NM_017914 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221588_x_at AI640855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI640855 /FEA=EST /DB_XREF=gi:4703964 /DB_XREF=est:wa27c11.x1 /CLONE=IMAGE:2299316 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:AF130089.1 AI640855 aldehyde dehydrogenase 6 family, member A1 ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 221589_s_at AW612403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW612403 /FEA=EST /DB_XREF=gi:7317589 /DB_XREF=est:hh01b05.x1 /CLONE=IMAGE:2953809 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:AF130089.1 AW612403 aldehyde dehydrogenase 6 family, member A1 ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 221590_s_at AF130089 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130089.1 /DEF=Homo sapiens clone FLB9440 PRO2550 mRNA, complete cds. /FEA=mRNA /PROD=PRO2550 /DB_XREF=gi:11493482 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:AF130089.1 AF130089 aldehyde dehydrogenase 6 family, member A1 ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 221591_s_at BC005004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005004.1 /DEF=Homo sapiens, hypothetical protein FLJ10491, clone MGC:961, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10491 /DB_XREF=gi:13436475 /UG=Hs.86211 hypothetical protein /FL=gb:BC005004.1 BC005004 family with sequence similarity 64, member A FAM64A 54478 NM_001195228 /// NM_019013 /// XM_006721549 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221592_at BC001663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001663.1 /DEF=Homo sapiens, Similar to ribosomal protein L31, clone MGC:1641, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein L31 /DB_XREF=gi:12804504 /UG=Hs.164170 vascular Rab-GAPTBC-containing /FL=gb:BC001663.1 BC001663 TBC1 domain family, member 8 (with GRAM domain) TBC1D8 11138 NM_001102426 /// NM_007063 /// XM_005263862 /// XM_005263863 /// XM_005263864 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 221593_s_at BC001663 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001663.1 /DEF=Homo sapiens, Similar to ribosomal protein L31, clone MGC:1641, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein L31 /DB_XREF=gi:12804504 /UG=Hs.164170 vascular Rab-GAPTBC-containing /FL=gb:BC001663.1 BC001663 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 221594_at AL136619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136619.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564O0523 (from clone DKFZp564O0523); complete cds. /FEA=mRNA /GEN=DKFZp564O0523 /PROD=hypothetical protein /DB_XREF=gi:12052763 /UG=Hs.21590 Homo sapiens mRNA; cDNA DKFZp564O0523 (from clone DKFZp564O0523); complete cds /FL=gb:AL136619.1 AL136619 RNA binding motif protein 48 RBM48 84060 NM_032120 /// XM_005250636 /// XM_006716149 /// XM_006716150 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 221595_at AL527334 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL527334 /FEA=EST /DB_XREF=gi:12790827 /DB_XREF=est:AL527334 /CLONE=CS0DC021YJ19 (3 prime) /UG=Hs.21590 Homo sapiens mRNA; cDNA DKFZp564O0523 (from clone DKFZp564O0523); complete cds /FL=gb:AL136619.1 AL527334 RNA binding motif protein 48 RBM48 84060 NM_032120 /// XM_005250636 /// XM_006716149 /// XM_006716150 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 221596_s_at AL136619 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136619.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564O0523 (from clone DKFZp564O0523); complete cds. /FEA=mRNA /GEN=DKFZp564O0523 /PROD=hypothetical protein /DB_XREF=gi:12052763 /UG=Hs.21590 Homo sapiens mRNA; cDNA DKFZp564O0523 (from clone DKFZp564O0523); complete cds /FL=gb:AL136619.1 AL136619 RNA binding motif protein 48 RBM48 84060 NM_032120 /// XM_005250636 /// XM_006716149 /// XM_006716150 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 221597_s_at BC003080 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003080.1 /DEF=Homo sapiens, Similar to HSPC171 protein, clone MGC:770, mRNA, complete cds. /FEA=mRNA /PROD=Similar to HSPC171 protein /DB_XREF=gi:13111781 /UG=Hs.279593 HSPC171 protein /FL=gb:BC003080.1 BC003080 transmembrane protein 208 TMEM208 29100 NM_014187 /// XR_243404 0006914 // autophagy // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221598_s_at BC002878 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002878.1 /DEF=Homo sapiens, Similar to cofactor required for Sp1 transcriptional activation, subunit 8 (34kD), clone MGC:11274, mRNA, complete cds. /FEA=mRNA /PROD=Similar to cofactor required for Sp1transcriptional activation, subunit 8 (34kD) /DB_XREF=gi:12804050 /UG=Hs.28166 cofactor required for Sp1 transcriptional activation, subunit 8 (34kD) /FL=gb:BC002878.1 gb:AF104252.1 gb:NM_004269.1 gb:AF230382.1 BC002878 mediator complex subunit 27 MED27 9442 NM_001253881 /// NM_001253882 /// NM_004269 /// XM_005272236 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay 221599_at BC002752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002752.1 /DEF=Homo sapiens, Similar to PTD015 protein, clone MGC:3367, mRNA, complete cds. /FEA=mRNA /PROD=Similar to PTD015 protein /DB_XREF=gi:12803822 /UG=Hs.95870 PTD015 protein /FL=gb:BC002752.1 BC002752 adipogenesis associated, Mth938 domain containing AAMDC 28971 NM_024684 /// XM_005273938 0043066 // negative regulation of apoptotic process // not recorded /// 0045600 // positive regulation of fat cell differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity 221600_s_at BC002752 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002752.1 /DEF=Homo sapiens, Similar to PTD015 protein, clone MGC:3367, mRNA, complete cds. /FEA=mRNA /PROD=Similar to PTD015 protein /DB_XREF=gi:12803822 /UG=Hs.95870 PTD015 protein /FL=gb:BC002752.1 BC002752 adipogenesis associated, Mth938 domain containing AAMDC 28971 NM_024684 /// XM_005273938 0043066 // negative regulation of apoptotic process // not recorded /// 0045600 // positive regulation of fat cell differentiation // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // not recorded 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity 221601_s_at AI084226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI084226 /FEA=EST /DB_XREF=gi:3422649 /DB_XREF=est:oy72g09.x1 /CLONE=IMAGE:1671424 /UG=Hs.58831 regulator of Fas-induced apoptosis /FL=gb:AF057557.1 gb:NM_005449.1 AI084226 Fas apoptotic inhibitory molecule 3 FAIM3 9214 NM_001142472 /// NM_001142473 /// NM_001193338 /// NM_005449 /// XM_005273351 /// XM_005273352 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221602_s_at AF057557 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF057557.1 /DEF=Homo sapiens anti-Fas-induced apoptosis (TOSO) mRNA, complete cds. /FEA=mRNA /GEN=TOSO /PROD=anti-Fas-induced apoptosis /DB_XREF=gi:3169292 /UG=Hs.58831 regulator of Fas-induced apoptosis /FL=gb:AF057557.1 gb:NM_005449.1 AF057557 Fas apoptotic inhibitory molecule 3 FAIM3 9214 NM_001142472 /// NM_001142473 /// NM_001193338 /// NM_005449 /// XM_005273351 /// XM_005273352 0002376 // immune system process // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221603_at BC000467 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000467.1 /DEF=Homo sapiens, Similar to peroxisomal biogenesis factor 16, clone MGC:8550, mRNA, complete cds. /FEA=mRNA /PROD=Similar to peroxisomal biogenesis factor 16 /DB_XREF=gi:12653394 /UG=Hs.100915 peroxisomal biogenesis factor 16 /FL=gb:BC000467.1 BC000467 peroxisomal biogenesis factor 16 PEX16 9409 NM_004813 /// NM_057174 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0022615 // protein to membrane docking // inferred from direct assay /// 0032581 // ER-dependent peroxisome organization // inferred from direct assay /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0070972 // protein localization to endoplasmic reticulum // inferred from direct assay 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 221604_s_at AB016531 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB016531.1 /DEF=Homo sapiens PEX16 mRNA, complete cds. /FEA=mRNA /GEN=PEX16 /DB_XREF=gi:6681657 /UG=Hs.100915 peroxisomal biogenesis factor 16 /FL=gb:BC004356.1 gb:AF118240.1 gb:NM_004813.1 gb:AB016531.1 AB016531 peroxisomal biogenesis factor 16 PEX16 9409 NM_004813 /// NM_057174 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0022615 // protein to membrane docking // inferred from direct assay /// 0032581 // ER-dependent peroxisome organization // inferred from direct assay /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0070972 // protein localization to endoplasmic reticulum // inferred from direct assay 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 221605_s_at AF136970 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF136970.1 /DEF=Homo sapiens sarcosine oxidase mRNA, complete cds. /FEA=mRNA /PROD=sarcosine oxidase /DB_XREF=gi:12239317 /UG=Hs.271167 L-pipecolic acid oxidase /FL=gb:AF136970.1 AF136970 pipecolic acid oxidase PIPOX 51268 NM_016518 0033514 // L-lysine catabolic process to acetyl-CoA via L-pipecolate // inferred from direct assay /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005777 // peroxisome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0008115 // sarcosine oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050031 // L-pipecolate oxidase activity // inferred from direct assay /// 0050031 // L-pipecolate oxidase activity // non-traceable author statement 221606_s_at BC005342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005342.1 /DEF=Homo sapiens, nucleosomal binding protein 1, clone MGC:12433, mRNA, complete cds. /FEA=mRNA /PROD=nucleosomal binding protein 1 /DB_XREF=gi:13529139 /UG=Hs.282204 nucleosomal binding protein 1 /FL=gb:AF250329.1 gb:BC005342.1 BC005342 high mobility group nucleosome binding domain 5 HMGN5 79366 NM_030763 /// XM_006724688 /// XM_006724689 /// XM_006724690 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // non-traceable author statement /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221607_x_at BC001920 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001920.1 /DEF=Homo sapiens, actin, gamma 1, clone MGC:3728, mRNA, complete cds. /FEA=mRNA /PROD=actin, gamma 1 /DB_XREF=gi:12804934 /UG=Hs.14376 actin, gamma 1 /FL=gb:BC001920.1 BC001920 actin, beta /// actin, gamma 1 ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 221608_at AY009401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AY009401.1 /DEF=Homo sapiens WNT6 precursor (WNT6) mRNA, complete cds. /FEA=mRNA /GEN=WNT6 /PROD=WNT6 precursor /DB_XREF=gi:11693043 /UG=Hs.29764 wingless-type MMTV integration site family, member 6 /FL=gb:AY009401.1 gb:BC004329.1 AY009401 wingless-type MMTV integration site family, member 6 WNT6 7475 NM_006522 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009798 // axis specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0070172 // positive regulation of tooth mineralization // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0072079 // nephron tubule formation // inferred from electronic annotation /// 0072080 // nephron tubule development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded 221609_s_at AY009401 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY009401.1 /DEF=Homo sapiens WNT6 precursor (WNT6) mRNA, complete cds. /FEA=mRNA /GEN=WNT6 /PROD=WNT6 precursor /DB_XREF=gi:11693043 /UG=Hs.29764 wingless-type MMTV integration site family, member 6 /FL=gb:AY009401.1 gb:BC004329.1 AY009401 wingless-type MMTV integration site family, member 6 WNT6 7475 NM_006522 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009798 // axis specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0070172 // positive regulation of tooth mineralization // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0072079 // nephron tubule formation // inferred from electronic annotation /// 0072080 // nephron tubule development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded 221610_s_at BC000795 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000795.1 /DEF=Homo sapiens, hypothetical protein FLJ20234, clone MGC:4988, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20234 /DB_XREF=gi:12653994 /UG=Hs.194385 hypothetical protein FLJ20234 /FL=gb:BC000795.1 BC000795 signal transducing adaptor family member 2 STAP2 55620 NM_001013841 /// NM_017720 /// XM_005259592 /// XM_006722790 /// XM_006722791 /// XM_006722792 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 221611_s_at AY014283 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY014283.1 /DEF=Homo sapiens NYD-SP6 mRNA, complete cds. /FEA=mRNA /PROD=NYD-SP6 /DB_XREF=gi:13508445 /UG=Hs.30127 hypothetical protein /FL=gb:AY014283.1 AY014283 PHD finger protein 7 PHF7 51533 NM_001278221 /// NM_016483 /// NM_173341 /// XM_005265225 /// XM_005265226 /// XM_005265227 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221612_at AF225421 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225421.1 /DEF=Homo sapiens HT017 mRNA, complete cds. /FEA=mRNA /PROD=HT017 /DB_XREF=gi:9963844 /UG=Hs.36766 HT017 protein /FL=gb:NM_020678.1 gb:AF225421.1 AF225421 leucine-rich repeats and transmembrane domains 1 LRTM1 57408 NM_020678 /// XM_005265337 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221613_s_at AL136598 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136598.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F2116 (from clone DKFZp564F2116); complete cds. /FEA=mRNA /GEN=DKFZp564F2116 /PROD=hypothetical protein /DB_XREF=gi:13276696 /UG=Hs.83954 protein associated with PRK1 /FL=gb:AL136598.1 AL136598 zinc finger, AN1-type domain 6 ZFAND6 54469 NM_001242911 /// NM_001242912 /// NM_001242913 /// NM_001242914 /// NM_001242915 /// NM_001242916 /// NM_001242917 /// NM_001242918 /// NM_001242919 /// NM_019006 /// XM_006720574 0006625 // protein targeting to peroxisome // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221614_s_at BC005153 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005153.1 /DEF=Homo sapiens, Similar to rabphilin 3A-like (without C2 domains), clone MGC:3453, mRNA, complete cds. /FEA=mRNA /PROD=Similar to rabphilin 3A-like (without C2domains) /DB_XREF=gi:13477352 /UG=Hs.198551 rabphilin 3A-like (without C2 domains) /FL=gb:BC005153.1 BC005153 rabphilin 3A-like (without C2 domains) RPH3AL 9501 NM_001190411 /// NM_001190412 /// NM_001190413 /// NM_006987 /// XM_006721363 /// XM_006725251 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221615_at AF104013 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF104013.1 /DEF=Homo sapiens peptidyl-prolyl cis-trans isomerase E (PPIE) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=PPIE /PROD=peptidyl-prolyl cis-trans isomerase E /DB_XREF=gi:4406228 /UG=Hs.33251 peptidylprolyl isomerase E (cyclophilin E) /FL=gb:AF104013.1 AF104013 bone morphogenetic protein 8b BMP8B 656 NM_001720 /// XM_005271149 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 221616_s_at AF077053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF077053.1 /DEF=Homo sapiens neuronal cell death-related protein mRNA, complete cds. /FEA=mRNA /PROD=neuronal cell death-related protein /DB_XREF=gi:4689153 /UG=Hs.171723 neuronal cell death-related protein /FL=gb:AF077053.1 gb:NM_015975.1 gb:AF220509.1 AF077053 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa TAF9B 51616 NM_015975 /// XM_005262142 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221617_at AF077053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF077053.1 /DEF=Homo sapiens neuronal cell death-related protein mRNA, complete cds. /FEA=mRNA /PROD=neuronal cell death-related protein /DB_XREF=gi:4689153 /UG=Hs.171723 neuronal cell death-related protein /FL=gb:AF077053.1 gb:NM_015975.1 gb:AF220509.1 AF077053 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa TAF9B 51616 NM_015975 /// XM_005262142 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221618_s_at AF220509 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220509.1 /DEF=Homo sapiens transcription associated factor TAFII31L mRNA, complete cds. /FEA=mRNA /PROD=transcription associated factor TAFII31L /DB_XREF=gi:9963820 /UG=Hs.171723 neuronal cell death-related protein /FL=gb:AF077053.1 gb:NM_015975.1 gb:AF220509.1 AF220509 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa TAF9B 51616 NM_015975 /// XM_005262142 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator 0005634 // nucleus // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221619_s_at AF189289 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF189289.1 /DEF=Homo sapiens presenilin-associated protein mRNA, complete cds. /FEA=mRNA /PROD=presenilin-associated protein /DB_XREF=gi:6409315 /UG=Hs.279939 mitochondrial carrier homolog 1 /FL=gb:AF189289.1 AF189289 mitochondrial carrier 1 MTCH1 23787 NM_001271641 /// NM_014341 /// XM_005248978 /// XM_005248979 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from expression pattern /// 0045161 // neuronal ion channel clustering // non-traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221620_s_at AF061264 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF061264.1 /DEF=Homo sapiens brain my025 mRNA, complete cds. /FEA=mRNA /PROD=brain my025 /DB_XREF=gi:12001991 /UG=Hs.40065 hypothetical protein MGC4825 /FL=gb:AF061264.1 AF061264 apolipoprotein O APOO 79135 NM_024122 /// NR_026545 /// XM_006724516 /// XM_006724517 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 221621_at AF130050 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF130050.1 /DEF=Homo sapiens clone FLB3442 PRO0872 mRNA, complete cds. /FEA=mRNA /PROD=PRO0872 /DB_XREF=gi:11493406 /UG=Hs.172154 Homo sapiens clone FLB3442 PRO0872 mRNA, complete cds /FL=gb:AF130050.1 AF130050 microRNA 6516 /// small Cajal body-specific RNA 16 /// small nucleolar RNA host gene 20 (non-protein coding) MIR6516 /// SCARNA16 /// SNHG20 654434 /// 677781 /// 102466864 NR_003013 /// NR_027058 /// NR_106997 221622_s_at AF246240 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF246240.1 /DEF=Homo sapiens HT026 mRNA, complete cds. /FEA=mRNA /PROD=HT026 /DB_XREF=gi:12005514 /UG=Hs.24371 uncharacterized hypothalamus protein HT007 /FL=gb:AF246240.1 AF246240 transmembrane protein 126B TMEM126B 55863 NM_001193537 /// NM_001193538 /// NM_001256546 /// NM_001256547 /// NM_018480 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 221623_at AF229053 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF229053.1 /DEF=Homo sapiens chondroitin sulfate proteoglycan BEHABbrevican mRNA, GPI isoform, complete cds. /FEA=mRNA /PROD=chondroitin sulfate proteoglycan BEHABbrevican /DB_XREF=gi:10798902 /UG=Hs.6194 chondroitin sulfate proteoglycan BEHABbrevican /FL=gb:AF229053.1 AF229053 brevican BCAN 63827 NM_021948 /// NM_198427 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 221624_at AF195821 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF195821.1 /DEF=Homo sapiens Tng2 (TNG2) mRNA, complete cds. /FEA=mRNA /GEN=TNG2 /PROD=Tng2 /DB_XREF=gi:6319193 /UG=Hs.144519 T-cell leukemialymphoma 6 /FL=gb:AF195821.1 AF195821 T-cell leukemia/lymphoma 6 (non-protein coding) TCL6 27004 NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NR_028288 221625_at AL136548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL136548.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G18121 (from clone DKFZp761G18121); complete cds. /FEA=mRNA /GEN=DKFZp761G18121 /PROD=hypothetical protein /DB_XREF=gi:12052731 /UG=Hs.260180 Homo sapiens mRNA; cDNA DKFZp761G18121 (from clone DKFZp761G18121); complete cds /FL=gb:AL136548.1 AL136548 221626_at AL136548 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136548.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761G18121 (from clone DKFZp761G18121); complete cds. /FEA=mRNA /GEN=DKFZp761G18121 /PROD=hypothetical protein /DB_XREF=gi:12052731 /UG=Hs.260180 Homo sapiens mRNA; cDNA DKFZp761G18121 (from clone DKFZp761G18121); complete cds /FL=gb:AL136548.1 AL136548 zinc finger protein 506 ZNF506 440515 NM_001099269 /// NM_001145404 /// NM_001145405 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221627_at AF220123 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF220123.1 /DEF=Homo sapiens tripartite motif protein TRIM10 beta (TRIM10) mRNA, complete cds; alternatively spliced. /FEA=mRNA /GEN=TRIM10 /PROD=tripartite motif protein TRIM10 beta /DB_XREF=gi:12407414 /UG=Hs.274295 ring finger protein 9 /FL=gb:AF220123.1 AF220123 tripartite motif containing 10 TRIM10 10107 NM_006778 /// NM_052828 0030218 // erythrocyte differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221628_s_at AF326966 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF326966.1 /DEF=Homo sapiens cytokine-like nuclear factor n-pac mRNA, complete cds. /FEA=mRNA /PROD=cytokine-like nuclear factor n-pac /DB_XREF=gi:13194723 /UG=Hs.331584 Homo sapiens cytokine-like nuclear factor n-pac mRNA, complete cds /FL=gb:AF326966.1 AF326966 glyoxylate reductase 1 homolog (Arabidopsis) GLYR1 84656 NM_032569 /// XM_005255637 /// XM_005255638 /// XM_005255639 /// XM_005255640 /// XR_243321 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 221629_x_at AF151022 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF151022.1 /DEF=Homo sapiens HSPC188 mRNA, complete cds. /FEA=mRNA /PROD=HSPC188 /DB_XREF=gi:7106765 /UG=Hs.300224 hypothetical protein /FL=gb:AF151022.1 AF151022 HGH1 homolog (S. cerevisiae) HGH1 51236 NM_016458 221630_s_at AY004154 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY004154.1 /DEF=Homo sapiens DEAD box RNA helicase (VASA) mRNA, complete cds. /FEA=mRNA /GEN=VASA /PROD=DEAD box RNA helicase /DB_XREF=gi:9438226 /UG=Hs.97689 VASA protein /FL=gb:NM_024415.1 gb:AY004154.1 AY004154 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 DDX4 54514 NM_001142549 /// NM_001166533 /// NM_001166534 /// NM_019039 /// NM_024415 /// XM_005248545 /// XM_005248547 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030317 // sperm motility // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033391 // chromatoid body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071546 // pi-body // inferred from sequence or structural similarity /// 0071547 // piP-body // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221631_at AB032946 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032946.1 /DEF=Homo sapiens mRNA for KIAA1120 protein, partial cds. /FEA=mRNA /GEN=KIAA1120 /PROD=KIAA1120 protein /DB_XREF=gi:6329714 /UG=Hs.125116 calcium channel, voltage-dependent, alpha 1I subunit /FL=gb:AF142567.1 AB032946 calcium channel, voltage-dependent, T type, alpha 1I subunit CACNA1I 8911 NM_001003406 /// NM_021096 /// XM_006724348 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0030317 // sperm motility // not recorded /// 0030431 // sleep // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070509 // calcium ion import // not recorded /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0086010 // membrane depolarization during action potential // not recorded 0005886 // plasma membrane // not recorded /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // not recorded /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008332 // low voltage-gated calcium channel activity // non-traceable author statement 221632_s_at BC001074 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001074.1 /DEF=Homo sapiens, clone MGC:2706, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2706) /DB_XREF=gi:12654488 /UG=Hs.143638 WD repeat domain 4 /FL=gb:BC001074.1 BC001074 WD repeat domain 4 WDR4 10785 NM_001260474 /// NM_001260475 /// NM_001260476 /// NM_001260477 /// NM_018669 /// NM_033661 /// NR_048535 /// XM_006723959 0006400 // tRNA modification // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay 221633_at BC000473 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000473.1 /DEF=Homo sapiens, Similar to hypothetical protein 384D8_6, clone MGC:8640, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein 384D8_6 /DB_XREF=gi:12653406 /UG=Hs.180903 hypothetical protein 384D8_6 /FL=gb:BC000473.1 gb:BC001833.1 BC000473 non-SMC condensin II complex, subunit H2 NCAPH2 29781 NM_001185011 /// NM_014551 /// NM_152299 /// XM_005261912 0000278 // mitotic cell cycle // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from direct assay 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221634_at BC000596 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000596.1 /DEF=Homo sapiens, Similar to ribosomal protein L23a, clone MGC:2597, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein L23a /DB_XREF=gi:12653636 /UG=Hs.247828 Homo sapiens, Similar to ribosomal protein L23a, clone MGC:2597, mRNA, complete cds /FL=gb:BC000596.1 BC000596 CENPBD1 pseudogene 1 /// ribosomal protein L23a pseudogene 7 CENPBD1P1 /// RPL23AP7 65996 /// 118433 NM_023939 /// NR_000029 /// NR_024528 /// NR_024529 /// NR_024530 /// NR_024531 /// NR_026052 221636_s_at AL136931 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136931.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586G2122 (from clone DKFZp586G2122); complete cds. /FEA=mRNA /GEN=DKFZp586G2122 /PROD=hypothetical protein /DB_XREF=gi:12053356 /UG=Hs.307079 Homo sapiens mRNA; cDNA DKFZp586G2122 (from clone DKFZp586G2122); complete cds /FL=gb:AL136931.1 AL136931 mitochondrial amidoxime reducing component 2 MARC2 54996 NM_017898 /// XM_005273168 /// XM_006711407 /// XR_247029 0008152 // metabolic process // inferred from electronic annotation /// 0042126 // nitrate metabolic process // inferred from direct assay /// 0051410 // detoxification of nitrogen compound // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008940 // nitrate reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from direct assay 221637_s_at BC001434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001434.1 /DEF=Homo sapiens, clone MGC:2477, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2477) /DB_XREF=gi:12655158 /UG=Hs.9061 hypothetical protein MGC2477 /FL=gb:BC001434.1 BC001434 chromosome 11 open reading frame 48 /// uncharacterized LOC102288414 C11orf48 /// LOC102288414 79081 /// 102288414 NM_001286086 /// NM_024099 /// NR_104414 221638_s_at AF008937 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF008937.1 /DEF=Homo sapiens syntaxin-16C mRNA, complete cds. /FEA=mRNA /PROD=syntaxin-16C /DB_XREF=gi:2352817 /UG=Hs.102178 syntaxin 16 /FL=gb:AF008937.1 AF008937 syntaxin 16 STX16 8675 NM_001001433 /// NM_001001434 /// NM_001134772 /// NM_001134773 /// NM_001204868 /// NM_003763 /// NR_037941 /// NR_037942 /// NR_037943 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221639_x_at AF068846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF068846.1 /DEF=Homo sapiens scaffold attachment factor A (SAF-A) mRNA, complete cds. /FEA=mRNA /GEN=SAF-A /PROD=scaffold attachment factor A /DB_XREF=gi:3201999 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:AF068846.1 AF068846 uncharacterized LOC102723559 LOC102723559 102723559 XR_426180 /// XR_428147 /// XR_428148 /// XR_432158 221640_s_at AF274972 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274972.1 /DEF=Homo sapiens PIDD (PIDD) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=PIDD /PROD=PIDD /DB_XREF=gi:10130018 /UG=Hs.123136 leucine rich repeat and death domain containing protein /FL=gb:AF274972.1 AF274972 p53-induced death domain protein 1 PIDD1 55367 NM_018494 /// NM_145886 /// NM_145887 /// XM_005253005 /// XM_005253006 /// XM_005253007 /// XM_005253008 /// XM_006718258 /// XR_242813 /// XR_242814 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from direct assay 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221641_s_at AF241787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF241787.1 /DEF=Homo sapiens CGI16-iso mRNA, complete cds. /FEA=mRNA /PROD=CGI16-iso /DB_XREF=gi:12005490 /UG=Hs.18625 Mitochondrial Acyl-CoA Thioesterase /FL=gb:AF241787.1 AF241787 acyl-CoA thioesterase 9 ACOT9 23597 NM_001033583 /// NM_001037171 /// XM_005274470 /// XM_005274471 /// XM_005274472 0006637 // acyl-CoA metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity 0003986 // acetyl-CoA hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 221642_at BC002903 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002903.1 /DEF=Homo sapiens, clone MGC:10323, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10323) /DB_XREF=gi:12804100 /UG=Hs.23595 three prime repair exonuclease 1 /FL=gb:BC002903.1 BC002903 221643_s_at AF016005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF016005.1 /DEF=Homo sapiens chromosome 1 atrophin-1 related protein (DRPLA) mRNA, complete cds. /FEA=mRNA /GEN=DRPLA /PROD=atrophin-1 related protein /DB_XREF=gi:3411014 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF016005.1 AF016005 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221644_s_at BC003597 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003597.1 /DEF=Homo sapiens, Similar to AIM-1 protein, clone MGC:697, mRNA, complete cds. /FEA=mRNA /PROD=Similar to AIM-1 protein /DB_XREF=gi:13097809 /UG=Hs.278962 AIM-1 protein /FL=gb:BC003597.1 BC003597 solute carrier family 45, member 2 SLC45A2 51151 NM_001012509 /// NM_001297417 /// NM_016180 /// XM_005248311 0007601 // visual perception // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033162 // melanosome membrane // inferred from electronic annotation 221645_s_at M27877 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M27877.1 /DEF=Homo sapiens HPF1 protein, complete cds. /FEA=mRNA /PROD=HPF1 protein /DB_XREF=gi:341790 /UG=Hs.305953 zinc finger protein 83 (HPF1) /FL=gb:M27877.1 M27877 zinc finger protein 83 ZNF83 55769 NM_001105549 /// NM_001105550 /// NM_001105551 /// NM_001105552 /// NM_001105553 /// NM_001105554 /// NM_001242531 /// NM_001242538 /// NM_001277945 /// NM_001277946 /// NM_001277947 /// NM_001277948 /// NM_001277949 /// NM_001277951 /// NM_001277952 /// NM_018300 /// NR_003936 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 221646_s_at AF267859 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF267859.1 /DEF=Homo sapiens GL013 mRNA, complete cds. /FEA=mRNA /PROD=GL013 /DB_XREF=gi:12006044 /UG=Hs.323820 Homo sapiens GL013 mRNA, complete cds /FL=gb:AF267859.1 AF267859 zinc finger, DHHC-type containing 11 /// zinc finger, DHHC-type containing 11B ZDHHC11 /// ZDHHC11B 79844 /// 653082 NM_024786 /// XM_003118532 /// XM_005248369 /// XM_005248370 /// XM_005248372 /// XM_006710165 /// XM_006714499 /// XM_006726417 /// XR_427665 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019706 // protein-cysteine S-palmitoyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221647_s_at AL136935 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136935.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586O0222 (from clone DKFZp586O0222); complete cds. /FEA=mRNA /GEN=DKFZp586O0222 /PROD=hypothetical protein /DB_XREF=gi:12053364 /UG=Hs.7393 hypothetical protein from EUROIMAGE 1987170 /FL=gb:AL136935.1 AL136935 microRNA 6743 /// RIC8 guanine nucleotide exchange factor A MIR6743 /// RIC8A 60626 /// 102465445 NM_001286134 /// NM_021932 /// NR_106801 /// XM_005253052 /// XM_006718270 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0070586 // cell-cell adhesion involved in gastrulation // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221648_s_at AK025651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025651.1 /DEF=Homo sapiens cDNA: FLJ21998 fis, clone HEP06592, highly similar to AF151904 Homo sapiens CGI-146 protein mRNA. /FEA=mRNA /DB_XREF=gi:10438235 /UG=Hs.42409 CGI-146 protein /FL=gb:BC004485.1 AK025651 agmatine ureohydrolase (agmatinase) AGMAT 79814 NM_024758 0006595 // polyamine metabolic process // traceable author statement /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from electronic annotation /// 0033388 // putrescine biosynthetic process from arginine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0097055 // agmatine biosynthetic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008783 // agmatinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221649_s_at BC000535 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000535.1 /DEF=Homo sapiens, clone MGC:3007, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:3007) /DB_XREF=gi:12653526 /UG=Hs.65302 peter pan (Drosophila) homolog /FL=gb:BC000535.1 BC000535 peter pan homolog (Drosophila) /// PPAN-P2RY11 readthrough PPAN /// PPAN-P2RY11 56342 /// 692312 NM_001040664 /// NM_001198690 /// NM_020230 0001973 // adenosine receptor signaling pathway // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0023041 // neuronal signal transduction // inferred from direct assay /// 0035589 // G-protein coupled purinergic nucleotide receptor signaling pathway // inferred from electronic annotation /// 0071318 // cellular response to ATP // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0030594 // neurotransmitter receptor activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045028 // G-protein coupled purinergic nucleotide receptor activity // inferred from electronic annotation /// 0045031 // ATP-activated nucleotide receptor activity // inferred from direct assay 221650_s_at BC002694 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002694.1 /DEF=Homo sapiens, hypothetical protein FLJ20045, clone MGC:3462, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ20045 /DB_XREF=gi:12803716 /UG=Hs.87293 hypothetical protein FLJ20045 /FL=gb:BC002694.1 BC002694 mediator of RNA polymerase II transcription subunit 18-like /// mediator complex subunit 18 LOC100996782 /// MED18 54797 /// 100996782 NM_001127350 /// NM_017638 /// XM_003846750 /// XM_005245914 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221651_x_at BC005332 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005332.1 /DEF=Homo sapiens, Similar to immunoglobulin kappa constant, clone MGC:12418, mRNA, complete cds. /FEA=mRNA /PROD=Similar to immunoglobulin kappa constant /DB_XREF=gi:13529115 /UG=Hs.156110 immunoglobulin kappa constant /FL=gb:BC005332.1 gb:AF113887.1 BC005332 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221652_s_at AF274950 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF274950.1 /DEF=Homo sapiens PNAS-25 mRNA, complete cds. /FEA=mRNA /PROD=PNAS-25 /DB_XREF=gi:12751064 /UG=Hs.22595 hypothetical protein FLJ10637 /FL=gb:AF274950.1 AF274950 asunder spermatogenesis regulator ASUN 55726 NM_018164 /// XM_005253422 /// XM_006719106 /// XM_006719107 /// XR_242896 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0080154 // regulation of fertilization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 221653_x_at BC004395 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004395.1 /DEF=Homo sapiens, Similar to apolipoprotein L, clone MGC:10978, mRNA, complete cds. /FEA=mRNA /PROD=Similar to apolipoprotein L /DB_XREF=gi:13325155 /UG=Hs.241412 apolipoprotein L, 2 /FL=gb:BC004395.1 BC004395 apolipoprotein L, 2 APOL2 23780 NM_030882 /// NM_145637 /// XM_006724217 /// XM_006724218 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // non-traceable author statement /// 0006953 // acute-phase response // non-traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005102 // receptor binding // non-traceable author statement /// 0008035 // high-density lipoprotein particle binding // non-traceable author statement /// 0008289 // lipid binding // non-traceable author statement 221654_s_at AF077040 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF077040.1 /DEF=Homo sapiens SIH003 mRNA, complete cds. /FEA=mRNA /PROD=SIH003 /DB_XREF=gi:4689127 /UG=Hs.251636 ubiquitin specific protease 3 /FL=gb:AF077040.1 AF077040 ubiquitin specific peptidase 3 USP3 9960 NM_001256702 /// NM_006537 /// NR_046341 /// NR_046342 /// XM_005254816 /// XM_006720789 /// XM_006720790 /// XM_006720791 /// XM_006720792 0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0031647 // regulation of protein stability // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221655_x_at AF282167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF282167.1 /DEF=Homo sapiens DRC3 mRNA, complete cds. /FEA=mRNA /PROD=DRC3 /DB_XREF=gi:9944939 /UG=Hs.28907 hypothetical protein FLJ20258 /FL=gb:AF282167.1 AF282167 EPS8-like 1 EPS8L1 54869 NM_017729 /// NM_133180 /// NM_139204 /// XM_005259020 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from physical interaction 221656_s_at BC003073 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003073.1 /DEF=Homo sapiens, clone MGC:2899, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:2899) /DB_XREF=gi:13111771 /UG=Hs.116385 hypothetical protein FLJ10521 /FL=gb:BC003073.1 BC003073 Rho guanine nucleotide exchange factor (GEF) 10-like ARHGEF10L 55160 NM_001011722 /// NM_018125 /// XM_005245923 /// XM_005245924 /// XM_005245925 /// XM_005245926 /// XM_005245927 /// XM_005245928 /// XM_005245929 /// XM_006710727 /// XM_006710728 /// XM_006710729 /// XM_006710730 /// XM_006710731 /// XM_006710732 /// XM_006710733 /// XM_006710734 /// XR_426616 /// XR_426617 /// XR_426618 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 221657_s_at BC001719 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001719.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ20548, clone MGC:1024, mRNA, complete cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ20548 /DB_XREF=gi:12804594 /UG=Hs.125037 hypothetical protein FLJ20548 /FL=gb:BC001719.1 BC001719 ankyrin repeat and SOCS box containing 6 ASB6 140459 NM_001202403 /// NM_017873 /// NM_177999 /// XM_005251713 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221658_s_at AF269133 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF269133.1 /DEF=Homo sapiens novel interleukin receptor (NILR) mRNA, complete cds. /FEA=mRNA /GEN=NILR /PROD=novel interleukin receptor /DB_XREF=gi:10801190 /UG=Hs.210546 interleukin 21 receptor /FL=gb:AF269133.1 AF269133 interleukin 21 receptor IL21R 50615 NM_021798 /// NM_181078 /// NM_181079 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030101 // natural killer cell activation // non-traceable author statement /// 0038114 // interleukin-21-mediated signaling pathway // non-traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0001532 // interleukin-21 receptor activity // non-traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221659_s_at BC002778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002778.1 /DEF=Homo sapiens, Similar to myosin light chain 2, precursor lymphocyte-specific, clone MGC:3479, mRNA, complete cds. /FEA=mRNA /PROD=Similar to myosin light chain 2, precursorlymphocyte-specific /DB_XREF=gi:12803868 /UG=Hs.247831 Homo sapiens, Similar to myosin light chain 2, precursor lymphocyte-specific, clone MGC:3479, mRNA, complete cds /FL=gb:BC002778.1 BC002778 myosin, light chain 10, regulatory MYL10 93408 NM_138403 /// XM_005250694 0005739 // mitochondrion // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221660_at BC002778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002778.1 /DEF=Homo sapiens, Similar to myosin light chain 2, precursor lymphocyte-specific, clone MGC:3479, mRNA, complete cds. /FEA=mRNA /PROD=Similar to myosin light chain 2, precursorlymphocyte-specific /DB_XREF=gi:12803868 /UG=Hs.247831 Homo sapiens, Similar to myosin light chain 2, precursor lymphocyte-specific, clone MGC:3479, mRNA, complete cds /FL=gb:BC002778.1 BC002778 myosin, light chain 10, regulatory MYL10 93408 NM_138403 /// XM_005250694 0005739 // mitochondrion // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221661_at AF210455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF210455.1 /DEF=Homo sapiens organic anion transporter 2 mRNA, complete cds. /FEA=mRNA /PROD=organic anion transporter 2 /DB_XREF=gi:12003292 /UG=Hs.251395 solute carrier family 22 (organic anion transporter), member 7 /FL=gb:AF210455.1 AF210455 solute carrier family 22 (organic anion transporter), member 7 SLC22A7 10864 NM_006672 /// NM_153320 /// XM_006714970 /// XM_006714971 /// XM_006714972 /// XM_006714973 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015711 // organic anion transport // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 221662_s_at AF210455 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF210455.1 /DEF=Homo sapiens organic anion transporter 2 mRNA, complete cds. /FEA=mRNA /PROD=organic anion transporter 2 /DB_XREF=gi:12003292 /UG=Hs.251395 solute carrier family 22 (organic anion transporter), member 7 /FL=gb:AF210455.1 AF210455 solute carrier family 22 (organic anion transporter), member 7 SLC22A7 10864 NM_006672 /// NM_153320 /// XM_006714970 /// XM_006714971 /// XM_006714972 /// XM_006714973 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015711 // organic anion transport // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0035634 // response to stilbenoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0008514 // organic anion transmembrane transporter activity // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 221663_x_at AB045369 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB045369.1 /DEF=Homo sapiens mRNA for histamine H3 receptor HH3R, complete cds. /FEA=mRNA /PROD=histamine H3 receptor HH3R /DB_XREF=gi:12248409 /UG=Hs.251399 histamine receptor H3 /FL=gb:AB045369.1 AB045369 histamine receptor H3 HRH3 11255 NM_007232 /// XM_005260266 /// XM_005260267 /// XM_006723696 0001505 // regulation of neurotransmitter levels // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0014050 // negative regulation of glutamate secretion // inferred from electronic annotation /// 0014053 // negative regulation of gamma-aminobutyric acid secretion // inferred from electronic annotation /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0014063 // negative regulation of serotonin secretion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050890 // cognition // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004969 // histamine receptor activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation 221664_s_at AF154005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF154005.1 /DEF=Homo sapiens junction adhesion molecule mRNA, complete cds. /FEA=mRNA /PROD=junction adhesion molecule /DB_XREF=gi:5457118 /UG=Hs.286218 junctional adhesion molecule /FL=gb:AF154005.1 AF154005 F11 receptor F11R 50848 NM_016946 /// NM_144501 /// NM_144502 /// NM_144503 /// NM_144504 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221665_s_at BC004907 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004907.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 4632407K17 gene, clone MGC:4642, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 4632407K17 gene /DB_XREF=gi:13436193 /UG=Hs.28907 hypothetical protein FLJ20258 /FL=gb:BC004907.1 BC004907 EPS8-like 1 EPS8L1 54869 NM_017729 /// NM_133180 /// NM_139204 /// XM_005259020 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from physical interaction 221666_s_at BC004470 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC004470.1 /DEF=Homo sapiens, clone MGC:10332, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10332) /DB_XREF=gi:13325315 /UG=Hs.71869 apoptosis-associated speck-like protein containing a CARD /FL=gb:BC004470.1 BC004470 PYD and CARD domain containing PYCARD 29108 NM_013258 /// NM_145182 /// NM_145183 0001773 // myeloid dendritic cell activation // inferred from mutant phenotype /// 0002218 // activation of innate immune response // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from electronic annotation /// 0002277 // myeloid dendritic cell activation involved in immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002588 // positive regulation of antigen processing and presentation of peptide antigen via MHC class II // inferred from sequence or structural similarity /// 0002821 // positive regulation of adaptive immune response // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // non-traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010803 // regulation of tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0031647 // regulation of protein stability // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032688 // negative regulation of interferon-beta production // inferred from mutant phenotype /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032760 // positive regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042104 // positive regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0090197 // positive regulation of chemokine secretion // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from sequence or structural similarity /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype /// 2000778 // positive regulation of interleukin-6 secretion // inferred from mutant phenotype /// 2001056 // positive regulation of cysteine-type endopeptidase activity // inferred from direct assay /// 2001181 // positive regulation of interleukin-10 secretion // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0008385 // IkappaB kinase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0072558 // NLRP1 inflammasome complex // inferred from direct assay /// 0072559 // NLRP3 inflammasome complex // inferred from direct assay /// 0097169 // AIM2 inflammasome complex // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // non-traceable author statement /// 0032090 // Pyrin domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from electronic annotation 221667_s_at AF133207 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF133207.1 /DEF=Homo sapiens protein kinase (H11) mRNA, complete cds. /FEA=mRNA /GEN=H11 /PROD=protein kinase /DB_XREF=gi:5901654 /UG=Hs.111676 protein kinase H11; small stress protein-like protein HSP22 /FL=gb:AF133207.1 AF133207 heat shock 22kDa protein 8 HSPB8 26353 NM_014365 0006950 // response to stress // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 221668_s_at AF250288 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF250288.1 /DEF=Homo sapiens dynein axonemal intermediate chain (DNAI2) mRNA, complete cds. /FEA=mRNA /GEN=DNAI2 /PROD=dynein axonemal intermediate chain /DB_XREF=gi:11596126 /UG=Hs.147472 dynein intermediate chain 2 /FL=gb:AF250288.1 AF250288 dynein, axonemal, intermediate chain 2 DNAI2 64446 NM_001172810 /// NM_023036 /// XM_005257578 /// XR_429915 /// XR_429916 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from mutant phenotype /// 0005874 // microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0005930 // axoneme // inferred from mutant phenotype /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 221669_s_at BC001964 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC001964.1 /DEF=Homo sapiens, acyl-Coenzyme A dehydrogenase family, member 8, clone MGC:4966, mRNA, complete cds. /FEA=mRNA /PROD=acyl-Coenzyme A dehydrogenase family, member 8 /DB_XREF=gi:12805020 /UG=Hs.14791 acyl-Coenzyme A dehydrogenase family, member 8 /FL=gb:BC001964.1 BC001964 acyl-CoA dehydrogenase family, member 8 ACAD8 27034 NM_014384 /// XM_005271501 /// XM_005271503 /// XM_005271505 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006574 // valine catabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003995 // acyl-CoA dehydrogenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 221670_s_at AF156888 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF156888.1 /DEF=Homo sapiens LIM homeobox protein 3 isoform a (LHX3) mRNA, complete cds. /FEA=mRNA /GEN=LHX3 /PROD=LIM homeobox protein 3 isoform a /DB_XREF=gi:7110142 /UG=Hs.148427 LIM homeobox protein 3 /FL=gb:AF156888.1 AF156888 LIM homeobox 3 LHX3 8022 NM_014564 /// NM_178138 /// XM_005263410 /// XR_244777 0001890 // placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021520 // spinal cord motor neuron cell fate specification // inferred from electronic annotation /// 0021521 // ventral spinal cord interneuron specification // inferred from electronic annotation /// 0021526 // medial motor column neuron differentiation // inferred from electronic annotation /// 0021527 // spinal cord association neuron differentiation // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048839 // inner ear development // inferred from expression pattern 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221671_x_at M63438 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M63438.1 /DEF=Human Ig rearranged gamma chain mRNA, V-J-C region and complete cds. /FEA=mRNA /DB_XREF=gi:184847 /UG=Hs.156110 immunoglobulin kappa constant /FL=gb:M63438.1 M63438 immunoglobulin kappa locus /// immunoglobulin kappa constant IGK /// IGKC 3514 /// 50802 0001895 // retina homeostasis // inferred from expression pattern /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 221672_s_at BC003650 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC003650.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 1810044A24 gene, clone MGC:4737, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 1810044A24 gene /DB_XREF=gi:13177756 /UG=Hs.157240 Homo sapiens cDNA: FLJ22741 fis, clone HUV00774 /FL=gb:BC003650.1 BC003650 trafficking protein particle complex 9 TRAPPC9 83696 NM_001160372 /// NM_031466 /// XM_005251077 /// XM_006716664 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 221673_s_at AB042563 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042563.1 /DEF=Homo sapiens CSNK1G1L mRNA for casein kinase 1 gamma 1L, complete cds. /FEA=mRNA /GEN=CSNK1G1L /PROD=casein kinase 1 gamma 1L /DB_XREF=gi:11177009 /UG=Hs.157777 casein kinase 1, gamma 1 /FL=gb:AB042563.1 AB042563 casein kinase 1, gamma 1 CSNK1G1 53944 NM_022048 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 221674_s_at AF209929 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF209929.1 /DEF=Homo sapiens chordin variant 1 (CHRD) mRNA, complete cds, alternatively spliced. /FEA=mRNA /GEN=CHRD /PROD=chordin variant 1 /DB_XREF=gi:11494126 /UG=Hs.166186 chordin /FL=gb:AF209929.1 gb:AF209930.1 AF209929 chordin CHRD 8646 NM_003741 /// NM_177978 /// NM_177979 /// XM_005247848 /// XM_005247849 /// XM_005247850 /// XM_005247851 /// XR_427383 0001501 // skeletal system development // traceable author statement /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0021919 // BMP signaling pathway involved in spinal cord dorsal/ventral patterning // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0033504 // floor plate development // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0019955 // cytokine binding // non-traceable author statement /// 0045545 // syndecan binding // inferred from electronic annotation 221675_s_at AF195624 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF195624.1 /DEF=Homo sapiens cholinephosphotransferase 1 beta mRNA, complete cds. /FEA=mRNA /PROD=cholinephosphotransferase 1 beta /DB_XREF=gi:9502012 /UG=Hs.171889 cholinephosphotransferase 1 /FL=gb:AF195624.1 AF195624 choline phosphotransferase 1 CHPT1 56994 NM_020244 /// XM_005269036 /// XR_245946 0001558 // regulation of cell growth // non-traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // non-traceable author statement /// 0006663 // platelet activating factor biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // non-traceable author statement 0004142 // diacylglycerol cholinephosphotransferase activity // inferred from direct assay /// 0004142 // diacylglycerol cholinephosphotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221676_s_at BC002342 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC002342.1 /DEF=Homo sapiens, coronin, actin-binding protein, 1C, clone MGC:8518, mRNA, complete cds. /FEA=mRNA /PROD=coronin, actin-binding protein, 1C /DB_XREF=gi:12803080 /UG=Hs.17377 coronin, actin-binding protein, 1C /FL=gb:BC002342.1 BC002342 coronin, actin binding protein, 1C CORO1C 23603 NM_001105237 /// NM_001276471 /// NM_014325 0006909 // phagocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030036 // actin cytoskeleton organization // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // not recorded 221677_s_at AF232674 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF232674.1 /DEF=Homo sapiens B17 mRNA, complete cds. /FEA=mRNA /PROD=B17 /DB_XREF=gi:8118230 /UG=Hs.17834 downstream neighbor of SON /FL=gb:AF232674.1 AF232674 downstream neighbor of SON DONSON 29980 NM_017613 /// NM_145794 /// NM_145795 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 221678_at AF225418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225418.1 /DEF=Homo sapiens lipase mRNA, complete cds. /FEA=mRNA /PROD=lipase /DB_XREF=gi:9963838 /UG=Hs.20220 lipase protein /FL=gb:AF225418.1 AF225418 abhydrolase domain containing 6 ABHD6 57406 NM_020676 /// XM_005265334 /// XM_005265335 /// XM_005265336 0008152 // metabolic process // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 2000124 // regulation of endocannabinoid signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation 221679_s_at AF225418 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF225418.1 /DEF=Homo sapiens lipase mRNA, complete cds. /FEA=mRNA /PROD=lipase /DB_XREF=gi:9963838 /UG=Hs.20220 lipase protein /FL=gb:AF225418.1 AF225418 abhydrolase domain containing 6 ABHD6 57406 NM_020676 /// XM_005265334 /// XM_005265335 /// XM_005265336 0008152 // metabolic process // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 2000124 // regulation of endocannabinoid signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation 221680_s_at AF147782 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF147782.1 /DEF=Homo sapiens tel related Ets factor (TREF) mRNA, complete cds. /FEA=mRNA /GEN=TREF /PROD=tel related ets factor /DB_XREF=gi:4929426 /UG=Hs.272398 transcription factor ets /FL=gb:AF147782.1 AF147782 ets variant 7 ETV7 51513 NM_001207035 /// NM_001207036 /// NM_001207037 /// NM_001207038 /// NM_001207039 /// NM_001207040 /// NM_001207041 /// NM_016135 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221681_s_at AF094508 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF094508.1 /DEF=Homo sapiens dentin phosphoryn mRNA, complete cds. /FEA=mRNA /PROD=dentin phosphoryn /DB_XREF=gi:4322669 /UG=Hs.274465 dentin sialophosphoprotein /FL=gb:AF094508.1 AF094508 dentin sialophosphoprotein DSPP 1834 NM_014208 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005518 // collagen binding // traceable author statement 221682_s_at AF135156 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF135156.1 /DEF=Homo sapiens D-cadherin precursor, mRNA, complete cds. /FEA=mRNA /PROD=D-cadherin precursor /DB_XREF=gi:12002283 /UG=Hs.284253 protocadherin gamma subfamily B, 6 /FL=gb:AF135156.1 AF135156 protocadherin gamma subfamily B, 6 PCDHGB6 56100 NM_018926 /// NM_032100 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221683_s_at AF317887 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF317887.1 /DEF=Homo sapiens monoclonal antibody 3H11 antigen mRNA, complete cds. /FEA=mRNA /PROD=monoclonal antibody 3H11 antigen /DB_XREF=gi:12711597 /UG=Hs.288715 hypothetical protein FLJ13615 /FL=gb:AF317887.1 AF317887 centrosomal protein 290kDa CEP290 80184 NM_025114 /// XM_005269158 /// XM_005269160 /// XM_005269161 /// XM_006719609 /// XM_006719610 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0015031 // protein transport // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030814 // regulation of cAMP metabolic process // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0042462 // eye photoreceptor cell development // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0070201 // regulation of establishment of protein localization // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from sequence or structural similarity /// 0034451 // centriolar satellite // inferred from direct assay /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051011 // microtubule minus-end binding // inferred from direct assay 221684_s_at AF254868 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF254868.1 /DEF=Homo sapiens nyctalopin mRNA, complete cds. /FEA=mRNA /PROD=nyctalopin /DB_XREF=gi:11993320 /UG=Hs.302019 nyctalopin /FL=gb:AF254868.1 AF254868 nyctalopin NYX 60506 NM_022567 /// XM_005272632 0007601 // visual perception // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221685_s_at AF269167 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF269167.1 /DEF=Homo sapiens arsenite related gene 1 mRNA, complete cds. /FEA=mRNA /PROD=arsenite related gene 1 /DB_XREF=gi:9885350 /UG=Hs.32471 hypothetical protein FLJ20364 /FL=gb:AF269167.1 AF269167 spindle apparatus coiled-coil protein 1 SPDL1 54908 NM_017785 /// XM_005265938 /// XM_006714888 /// XM_006714889 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007080 // mitotic metaphase plate congression // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from electronic annotation /// 0034501 // protein localization to kinetochore // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0043515 // kinetochore binding // inferred from direct assay 221686_s_at AL136869 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136869.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434J0450 (from clone DKFZp434J0450); complete cds. /FEA=mRNA /GEN=DKFZp434J0450 /PROD=hypothetical protein /DB_XREF=gi:12053242 /UG=Hs.33818 RecQ protein-like 5 /FL=gb:AL136869.1 AL136869 RecQ protein-like 5 RECQL5 9400 NM_001003715 /// NM_001003716 /// NM_004259 /// XM_005257818 /// XM_005257822 /// XM_005257823 /// XM_006722186 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // non-traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // non-traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051304 // chromosome separation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221687_s_at BC000122 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC000122.1 /DEF=Homo sapiens, Similar to nuclear localization signals binding protein 1, clone MGC:3104, mRNA, complete cds. /FEA=mRNA /PROD=Similar to nuclear localization signals bindingprotein 1 /DB_XREF=gi:12652742 /UG=Hs.4914 Homo sapiens mRNA for FLJ00031 protein, partial cds /FL=gb:BC000122.1 BC000122 multivesicular body subunit 12B MVB12B 89853 NM_001011703 /// NM_033446 /// XM_005252297 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from mutant phenotype /// 0043130 // ubiquitin binding // inferred from direct assay 221688_s_at AL136913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AL136913.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L0118 (from clone DKFZp586L0118); complete cds. /FEA=mRNA /GEN=DKFZp586L0118 /PROD=hypothetical protein /DB_XREF=gi:12053320 /UG=Hs.6118 hypothetical protein FLJ10968 /FL=gb:AL136913.1 AL136913 IMP3, U3 small nucleolar ribonucleoprotein IMP3 55272 NM_018285 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221689_s_at AB035745 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB035745.1 /DEF=Homo sapiens mRNA for DSCR5b, complete cds. /FEA=mRNA /GEN=DSCR5b /PROD=DSCR5b /DB_XREF=gi:7798596 /UG=Hs.66493 Down syndrome critical region gene 5 /FL=gb:AB035745.1 gb:AB037163.1 gb:AF237812.1 AB035745 phosphatidylinositol glycan anchor biosynthesis, class P PIGP 51227 NM_153681 /// NM_153682 /// NR_028352 /// XM_005260990 /// XM_006724010 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from direct assay 221690_s_at AF298547 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF298547.1 /DEF=Homo sapiens nucleotide-binding site protein 1 mRNA, complete cds. /FEA=mRNA /PROD=nucleotide-binding site protein 1 /DB_XREF=gi:10198206 /UG=Hs.6844 hypothetical protein FLJ20510 /FL=gb:AF298547.1 AF298547 NLR family, pyrin domain containing 2 NLRP2 55655 NM_001174081 /// NM_001174082 /// NM_001174083 /// NM_017852 0006915 // apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0032090 // Pyrin domain binding // inferred from physical interaction 221691_x_at AB042278 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB042278.1 /DEF=Homo sapiens mRNA for nucleophosminB23.2, complete cds. /FEA=mRNA /PROD=nucleophosminB23.2 /DB_XREF=gi:13536990 /FL=gb:AB042278.1 AB042278 nucleophosmin (nucleolar phosphoprotein B23, numatrin) NPM1 4869 NM_001037738 /// NM_002520 /// NM_199185 /// XM_005265920 /// XM_006714869 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 221692_s_at AB049652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049652.1 /DEF=Homo sapiens MRPL34 mRNA for mitochondrial ribosomal protein L34 (L34mt), complete cds. /FEA=mRNA /GEN=MRPL34 /PROD=mitochondrial ribosomal protein L34 (L34mt) /DB_XREF=gi:13559395 /FL=gb:AB049652.1 AB049652 mitochondrial ribosomal protein L34 MRPL34 64981 NM_023937 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 221693_s_at AB049952 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AB049952.1 /DEF=Homo sapiens MRPS18a mRNA for mitochondrial ribosomal protein S18a, complete cds. /FEA=mRNA /GEN=MRPS18a /PROD=mitochondrial ribosomal protein S18a /DB_XREF=gi:13620904 /FL=gb:AB049952.1 AB049952 mitochondrial ribosomal protein S18A MRPS18A 55168 NM_001193343 /// NM_018135 /// XM_006715134 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005763 // mitochondrial small ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement 221695_s_at AF239798 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF239798.1 /DEF=Homo sapiens protein kinase MEKK2b mRNA, complete cds. /FEA=mRNA /PROD=protein kinase MEKK2b /DB_XREF=gi:7542556 /FL=gb:AF239798.1 AF239798 mitogen-activated protein kinase kinase kinase 2 MAP3K2 10746 NM_006609 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221696_s_at AF251059 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF251059.1 /DEF=Homo sapiens FGF receptor 4b mRNA, complete cds. /FEA=mRNA /PROD=FGF receptor 4b /DB_XREF=gi:13625179 /FL=gb:AF251059.1 AF251059 serine/threonine/tyrosine kinase 1 STYK1 55359 NM_018423 /// XM_005253417 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221697_at AF276659 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF276659.1 /DEF=Homo sapiens MAP1 light chain 3-like protein 2 mRNA, complete cds. /FEA=mRNA /PROD=MAP1 light chain 3-like protein 2 /DB_XREF=gi:13625772 /FL=gb:AF276659.1 AF276659 microtubule-associated protein 1 light chain 3 gamma MAP1LC3C 440738 NM_001004343 /// XM_005273139 0000045 // autophagic vacuole assembly // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0006995 // cellular response to nitrogen starvation // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0050811 // GABA receptor binding // not recorded 221698_s_at AF313468 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF313468.1 /DEF=Homo sapiens dendritic cell-associated C-type lectin-1 mRNA, complete cds. /FEA=mRNA /PROD=dendritic cell-associated C-type lectin-1 /DB_XREF=gi:13649707 /FL=gb:AF313468.1 AF313468 C-type lectin domain family 7, member A CLEC7A 64581 NM_022570 /// NM_197947 /// NM_197948 /// NM_197949 /// NM_197950 /// NM_197951 /// NM_197952 /// NM_197953 /// NM_197954 /// XM_005253467 /// XM_005253468 /// XM_006719135 /// XM_006719136 0001878 // response to yeast // inferred from electronic annotation /// 0001879 // detection of yeast // inferred from electronic annotation /// 0002238 // response to molecule of fungal origin // inferred from electronic annotation /// 0002366 // leukocyte activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002752 // cell surface pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0006910 // phagocytosis, recognition // inferred from direct assay /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008037 // cell recognition // inferred from direct assay /// 0009756 // carbohydrate mediated signaling // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0042110 // T cell activation // traceable author statement /// 0042832 // defense response to protozoan // non-traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0071226 // cellular response to molecule of fungal origin // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0001846 // opsonin binding // inferred from electronic annotation /// 0001872 // (1->3)-beta-D-glucan binding // inferred from electronic annotation /// 0001874 // (1->3)-beta-D-glucan receptor activity // inferred from electronic annotation /// 0008329 // signaling pattern recognition receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from direct assay /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221699_s_at AF334103 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF334103.1 /DEF=Homo sapiens nucleolar protein GU2 mRNA, complete cds. /FEA=mRNA /PROD=nucleolar protein GU2 /DB_XREF=gi:13540303 /FL=gb:AF334103.1 AF334103 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 DDX50 79009 NM_024045 /// XM_005270148 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221700_s_at AF348700 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF348700.1 /DEF=Homo sapiens ubiquitin A-52 residue ribosomal protein fusion product 1 (UBA52), mRNA, complete cds. /FEA=mRNA /GEN=UBA52 /PROD=ubiquitin A-52 residue ribosomal protein fusionproduct 1 /DB_XREF=gi:13569611 /FL=gb:AF348700.1 AF348700 ubiquitin A-52 residue ribosomal protein fusion product 1 UBA52 7311 NM_001033930 /// NM_003333 /// XM_005260050 /// XM_005260051 /// XM_005260052 /// XM_005260053 /// XM_005260054 /// XM_006722871 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221701_s_at AF352728 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF352728.1 /DEF=Homo sapiens STRA6 isoform 1 mRNA, complete cds, alternatively spliced. /FEA=mRNA /PROD=STRA6 isoform 1 /DB_XREF=gi:13560965 /FL=gb:AF352728.1 AF352728 stimulated by retinoic acid 6 STRA6 64220 NM_001142617 /// NM_001142618 /// NM_001142619 /// NM_001142620 /// NM_001199040 /// NM_001199041 /// NM_001199042 /// NM_022369 0001523 // retinoid metabolic process // traceable author statement /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from mutant phenotype /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0003281 // ventricular septum development // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007603 // phototransduction, visible light // traceable author statement /// 0007612 // learning // inferred from mutant phenotype /// 0007631 // feeding behavior // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0030325 // adrenal gland development // inferred from mutant phenotype /// 0030540 // female genitalia development // inferred from mutant phenotype /// 0042297 // vocal learning // inferred from mutant phenotype /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation /// 0043583 // ear development // inferred from mutant phenotype /// 0043585 // nose morphogenesis // inferred from mutant phenotype /// 0048286 // lung alveolus development // inferred from mutant phenotype /// 0048520 // positive regulation of behavior // inferred from mutant phenotype /// 0048546 // digestive tract morphogenesis // inferred from mutant phenotype /// 0048566 // embryonic digestive tract development // inferred from mutant phenotype /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048745 // smooth muscle tissue development // inferred from mutant phenotype /// 0048844 // artery morphogenesis // inferred from mutant phenotype /// 0050890 // cognition // inferred from mutant phenotype /// 0050905 // neuromuscular process // inferred from mutant phenotype /// 0051180 // vitamin transport // inferred from electronic annotation /// 0060322 // head development // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype /// 0060325 // face morphogenesis // inferred from mutant phenotype /// 0060426 // lung vasculature development // inferred from mutant phenotype /// 0060539 // diaphragm development // inferred from mutant phenotype /// 0060900 // embryonic camera-type eye formation // inferred from mutant phenotype /// 0061029 // eyelid development in camera-type eye // inferred from mutant phenotype /// 0061038 // uterus morphogenesis // inferred from mutant phenotype /// 0061143 // alveolar primary septum development // inferred from mutant phenotype /// 0061156 // pulmonary artery morphogenesis // inferred from mutant phenotype /// 0061205 // paramesonephric duct development // inferred from mutant phenotype /// 0071939 // vitamin A import // inferred from electronic annotation /// 0097070 // ductus arteriosus closure // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0051183 // vitamin transporter activity // inferred from electronic annotation 221702_s_at AF353992 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF353992.1 /DEF=Homo sapiens BBP-like protein 2 (BLP2) mRNA, complete cds. /FEA=mRNA /GEN=BLP2 /PROD=BBP-like protein 2 /DB_XREF=gi:13625462 /FL=gb:AF353992.1 AF353992 TM2 domain containing 3 TM2D3 80213 NM_025141 /// NM_078474 /// XM_005254980 /// XM_005254981 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221703_at AF360549 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF360549.1 /DEF=Homo sapiens BRCA1-binding helicase-like protein BACH1 mRNA, complete cds. /FEA=mRNA /PROD=BRCA1-binding helicase-like protein BACH1 /DB_XREF=gi:13661818 /FL=gb:AF360549.1 AF360549 BRCA1 interacting protein C-terminal helicase 1 BRIP1 83990 NM_032043 0000077 // DNA damage checkpoint // non-traceable author statement /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 221704_s_at BC005882 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005882.1 /DEF=Homo sapiens, hypothetical protein FLJ12750, clone MGC:4691, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ12750 /DB_XREF=gi:13543447 /FL=gb:BC005882.1 BC005882 vacuolar protein sorting 37 homolog B (S. cerevisiae) VPS37B 79720 NM_024667 /// XM_005253621 /// XM_005253622 /// XM_006719602 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement 0000813 // ESCRT I complex // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221705_s_at BC005934 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC005934.1 /DEF=Homo sapiens, hypothetical protein FLJ21168, clone MGC:14549, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ21168 /DB_XREF=gi:13543553 /FL=gb:BC005934.1 BC005934 suppressor of IKBKE 1 SIKE1 80143 NM_001102396 /// NM_025073 /// NR_049741 /// NR_049742 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221706_s_at BC006005 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006005.1 /DEF=Homo sapiens, Similar to uncharacterized hematopoietic stemprogenitor cells protein MDS032, clone MGC:14828, mRNA, complete cds. /FEA=mRNA /PROD=Similar to uncharacterized hematopoieticstemprogenitor cells protein MDS032 /DB_XREF=gi:13543708 /FL=gb:BC006005.1 BC006005 unconventional SNARE in the ER 1 homolog (S. cerevisiae) USE1 55850 NM_018467 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007041 // lysosomal transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from sequence or structural similarity /// 0032940 // secretion by cell // inferred from sequence or structural similarity /// 0060628 // regulation of ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0071786 // endoplasmic reticulum tubular network organization // inferred from electronic annotation 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221707_s_at BC006116 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006116.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 3100002B05 gene, clone MGC:12993, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 3100002B05 gene /DB_XREF=gi:13543951 /FL=gb:BC006116.1 BC006116 vacuolar protein sorting 53 homolog (S. cerevisiae) VPS53 55275 NM_001128159 /// NM_018289 /// XM_005256715 /// XM_005256716 /// XM_006721554 /// XM_006721555 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000938 // GARP complex // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221708_s_at BC006214 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006214.1 /DEF=Homo sapiens, clone MGC:999, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:999) /DB_XREF=gi:13623232 /FL=gb:BC006214.1 BC006214 unc-45 homolog A (C. elegans) UNC45A 55898 NM_001039675 /// NM_017979 /// NM_018671 /// XM_005254963 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from electronic annotation 221709_s_at BC006222 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006222.1 /DEF=Homo sapiens, clone MGC:10279, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10279) /DB_XREF=gi:13623244 /FL=gb:BC006222.1 BC006222 zinc finger protein 839 ZNF839 55778 NM_001267827 /// NM_001267828 /// NM_018335 /// XM_005267850 /// XM_006720202 /// XM_006720203 0046872 // metal ion binding // inferred from electronic annotation 221710_x_at BC006241 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006241.1 /DEF=Homo sapiens, hypothetical protein FLJ10647, clone MGC:11318, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10647 /DB_XREF=gi:13623280 /FL=gb:BC006241.1 BC006241 eva-1 homolog B (C. elegans) EVA1B 55194 NM_018166 /// XM_005270998 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221711_s_at BC006244 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006244.1 /DEF=Homo sapiens, HSPC142 protein, clone MGC:11295, mRNA, complete cds. /FEA=mRNA /PROD=HSPC142 protein /DB_XREF=gi:13623286 /FL=gb:BC006244.1 BC006244 BRISC and BRCA1 A complex member 1 BABAM1 29086 NM_001033549 /// NM_001288756 /// NM_001288757 /// NM_014173 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay /// 0070552 // BRISC complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221712_s_at BC006351 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006351.1 /DEF=Homo sapiens, clone MGC:12596, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:12596) /DB_XREF=gi:13623492 /FL=gb:BC006351.1 BC006351 WD repeat domain 74 WDR74 54663 NM_018093 /// XM_005274055 0001825 // blastocyst formation // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221713_s_at BC006434 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006434.1 /DEF=Homo sapiens, hypothetical protein FLJ12748, clone MGC:13089, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ12748 /DB_XREF=gi:13623628 /FL=gb:BC006434.1 BC006434 MAP6 domain containing 1 MAP6D1 79929 NM_024871 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation /// 0018009 // N-terminal peptidyl-L-cysteine N-palmitoylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005516 // calmodulin binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 221714_s_at BC006441 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:BC006441.1 /DEF=Homo sapiens, Similar to RNA polymerase I transcription factor RRN3, clone MGC:13169, mRNA, complete cds. /FEA=mRNA /PROD=Similar to RNA polymerase I transcription factorRRN3 /DB_XREF=gi:13623642 /FL=gb:BC006441.1 BC006441 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 RRN3P1 730092 NR_003370 221715_at Z25437 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:Z25437.1 /DEF=H.sapiens protein-tyrosine kinase gene, complete CDS. /FEA=mRNA /PROD=protein-tyrosine kinase /DB_XREF=gi:405752 /FL=gb:Z25437.1 Z25437 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 221716_s_at AY009107 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AY009107.1 /DEF=Homo sapiens PRTD-NY3 mRNA, complete cds. /FEA=mRNA /PROD=PRTD-NY3 /DB_XREF=gi:12330997 /UG=Hs.99344 hypothetical protein PRTD-NY3 /FL=gb:AY009107.1 AY009107 acyl-CoA synthetase bubblegum family member 2 ACSBG2 81616 NM_001289177 /// NM_001289178 /// NM_001289179 /// NM_001289180 /// NM_030924 /// XM_005259653 /// XM_006722915 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay 221717_at L25664 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L25664.1 /DEF=Human interferon mRNA, complete cds. /FEA=CDS /PROD=interferon /DB_XREF=gi:479010 /UG=Hs.247726 Human interferon mRNA, complete cds /FL=gb:L25664.1 L25664 221718_s_at M90360 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:M90360.1 /DEF=Human type II cAMP-dependent protein kinase (Ht31) mRNA, complete cds. /FEA=CDS /GEN=Ht31 /PROD=protein kinase /DB_XREF=gi:184434 /FL=gb:M90360.1 M90360 A kinase (PRKA) anchor protein 13 AKAP13 11214 NM_001270546 /// NM_006738 /// NM_007200 /// NM_144767 /// XM_005254839 /// XM_005254840 /// XM_005254841 /// XM_005254842 /// XM_005254843 /// XM_005254844 /// XM_005254845 /// XM_005254846 /// XM_005254847 /// XM_005254848 /// XM_005254849 /// XM_005254850 /// XM_005254851 /// XM_005254852 /// XM_005254853 /// XM_005254854 /// XM_005254855 /// XM_005254856 /// XM_006720376 /// XM_006720377 /// XM_006720378 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 221719_s_at AF123654 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123654.1 /DEF=Homo sapiens clone E264162 FEZ1 (FEZ1) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=FEZ1 /PROD=FEZ1 /DB_XREF=gi:4572465 /UG=Hs.93605 leucine zipper, putative tumor suppressor 1 /FL=gb:AF123654.1 AF123654 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221720_s_at L11573 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:L11573.1 /DEF=Human surfactant protein B mRNA, complete cds. /FEA=CDS /PROD=33.1 kDa protein /DB_XREF=gi:1220354 /FL=gb:L11573.1 L11573 0007585 // respiratory gaseous exchange // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009152 // purine ribonucleotide biosynthetic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221721_s_at AF123656 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123656.1 /DEF=Homo sapiens clone D14 FEZ1 (FEZ1) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=FEZ1 /PROD=FEZ1 /DB_XREF=gi:4572469 /UG=Hs.93605 leucine zipper, putative tumor suppressor 1 /FL=gb:AF123656.1 AF123656 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221722_x_at AF123652 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF123652.1 /DEF=Homo sapiens clone E16T8 FEZ1 (FEZ1) mRNA, alternatively spliced, complete cds. /FEA=CDS /GEN=FEZ1 /PROD=FEZ1 /DB_XREF=gi:4572461 /UG=Hs.93605 leucine zipper, putative tumor suppressor 1 /FL=gb:AF123652.1 AF123652 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221723_s_at AF243499 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF243499.2 /DEF=Homo sapiens sodium bicarbonate cotransporter NBC4a (NBC4) mRNA, complete cds. /FEA=CDS /GEN=NBC4 /PROD=sodium bicarbonate cotransporter NBC4a /DB_XREF=gi:13486616 /UG=Hs.321127 sodium bicarbonate transporter 4 /FL=gb:AF243499.2 AF243499 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 SLC4A5 57835 NM_021196 /// NM_033323 /// NM_133478 /// NM_133479 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005869 // dynactin complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation 221724_s_at AF200738 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank gb:AF200738.1 /DEF=Homo sapiens C-type lectin DDB27 short form (DDB27) mRNA, complete cds. /FEA=CDS /GEN=DDB27 /PROD=C-type lectin DDB27 short form /DB_XREF=gi:11493653 /UG=Hs.115515 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 /FL=gb:AF200738.1 AF200738 C-type lectin domain family 4, member A CLEC4A 50856 NM_016184 /// NM_194447 /// NM_194448 /// NM_194450 0002376 // immune system process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0030246 // carbohydrate binding // inferred from electronic annotation 221725_at AI962978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI962978 /FEA=EST /DB_XREF=gi:5755691 /DB_XREF=est:wt25f05.x1 /CLONE=IMAGE:2508513 /UG=Hs.288908 WAS protein family, member 2 /FL=gb:NM_006990.1 gb:AB026542.1 AI962978 WAS protein family, member 2 WASF2 10163 NM_001201404 /// NM_006990 0001505 // regulation of neurotransmitter levels // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0031209 // SCAR complex // inferred from mutant phenotype /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004969 // histamine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from mutant phenotype 221726_at BE250348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE250348 /FEA=EST /DB_XREF=gi:9120458 /DB_XREF=est:600943342T1 /CLONE=IMAGE:2959811 /UG=Hs.326249 Homo sapiens mRNA; cDNA DKFZp586E0524 (from clone DKFZp586E0524) BE250348 ribosomal protein L22 RPL22 6146 NM_000983 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221727_at AA456973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA456973 /FEA=EST /DB_XREF=gi:2179693 /DB_XREF=est:aa90g11.s1 /CLONE=IMAGE:838628 /UG=Hs.74861 activated RNA polymerase II transcription cofactor 4 AA456973 SUB1 homolog (S. cerevisiae) SUB1 10923 NM_006713 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221728_x_at AA628440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA628440 /FEA=EST /DB_XREF=gi:2540827 /DB_XREF=est:af26f02.s1 /CLONE=IMAGE:1032795 /UG=Hs.83623 nuclear receptor subfamily 1, group I, member 3 AA628440 X inactive specific transcript (non-protein coding) XIST 7503 NR_001564 221729_at AL575735 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL575735 /FEA=EST /DB_XREF=gi:12937190 /DB_XREF=est:AL575735 /CLONE=CS0DI070YK23 (3 prime) /UG=Hs.82985 collagen, type V, alpha 2 /FL=gb:NM_000393.1 AL575735 collagen, type V, alpha 2 COL5A2 1290 NM_000393 0001501 // skeletal system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030574 // collagen catabolic process // traceable author statement /// 0043588 // skin development // inferred from mutant phenotype /// 0043588 // skin development // inferred from sequence or structural similarity /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // non-traceable author statement 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221730_at NM_000393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000393.1 /DEF=Homo sapiens collagen, type V, alpha 2 (COL5A2), mRNA. /FEA=CDS /GEN=COL5A2 /PROD=collagen, type V, alpha 2 /DB_XREF=gi:4502958 /UG=Hs.82985 collagen, type V, alpha 2 /FL=gb:NM_000393.1 NM_000393 collagen, type V, alpha 2 COL5A2 1290 NM_000393 0001501 // skeletal system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030574 // collagen catabolic process // traceable author statement /// 0043588 // skin development // inferred from mutant phenotype /// 0043588 // skin development // inferred from sequence or structural similarity /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // non-traceable author statement 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221731_x_at BF218922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF218922 /FEA=EST /DB_XREF=gi:11112418 /DB_XREF=est:601885091F1 /CLONE=IMAGE:4103447 /UG=Hs.81800 chondroitin sulfate proteoglycan 2 (versican) BF218922 versican VCAN 1462 NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385 0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 221732_at AK026161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026161.1 /DEF=Homo sapiens cDNA: FLJ22508 fis, clone HRC11772. /FEA=mRNA /DB_XREF=gi:10438922 /UG=Hs.8859 Homo sapiens, Similar to RIKEN cDNA 5830420C20 gene, clone IMAGE:3633379, mRNA, partial cds AK026161 calcium activated nucleotidase 1 CANT1 124583 NM_001159772 /// NM_001159773 /// NM_138793 /// XM_005257020 /// XM_005257021 /// XM_005257022 /// XM_006721682 /// XM_006721683 /// XR_243633 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221733_s_at BE546897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE546897 /FEA=EST /DB_XREF=gi:9775542 /DB_XREF=est:601073940F1 /CLONE=IMAGE:3460089 /UG=Hs.6880 DKFZP434D156 protein BE546897 G patch domain containing 4 GPATCH4 54865 NM_015590 /// NM_017725 /// NM_182679 /// XM_005245287 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221734_at BE328312 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE328312 /FEA=EST /DB_XREF=gi:9202173 /DB_XREF=est:hs95d12.x1 /CLONE=IMAGE:3144983 /UG=Hs.6614 ESTs, Weakly similar to A43932 mucin 2 precursor, intestinal H.sapiens BE328312 proline-rich coiled-coil 1 PRRC1 133619 NM_001286808 /// NM_130809 /// XM_006714529 0005794 // Golgi apparatus // inferred from electronic annotation 221735_at H04342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H04342 /FEA=EST /DB_XREF=gi:867275 /DB_XREF=est:yj10g11.s1 /CLONE=IMAGE:148388 /UG=Hs.109778 KIAA1449 protein H04342 WD repeat domain 48 WDR48 57599 NM_020839 /// XM_005265346 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221736_at AA156777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA156777 /FEA=EST /DB_XREF=gi:1728392 /DB_XREF=est:zl18c08.s1 /CLONE=IMAGE:502286 /UG=Hs.25431 KIAA1219 protein AA156777 Ral GTPase activating protein, beta subunit (non-catalytic) RALGAPB 57148 NM_001282917 /// NM_001282918 /// NM_020336 /// XM_005260462 /// XM_005260463 /// XM_005260464 /// XM_005260465 0032484 // Ral protein signal transduction // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0017123 // Ral GTPase activator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 221737_at AK024696 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024696.1 /DEF=Homo sapiens cDNA: FLJ21043 fis, clone CAE11633. /FEA=mRNA /DB_XREF=gi:10437043 /UG=Hs.182874 guanine nucleotide binding protein (G protein) alpha 12 /FL=gb:L01694.1 gb:NM_007353.1 AK024696 guanine nucleotide binding protein (G protein) alpha 12 GNA12 2768 NM_001282440 /// NM_001282441 /// NM_001293092 /// NM_007353 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // not recorded /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0010762 // regulation of fibroblast migration // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031526 // brush border membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031752 // D5 dopamine receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 221738_at BG236163 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG236163 /FEA=EST /DB_XREF=gi:12750094 /DB_XREF=est:naf25a08.x1 /CLONE=IMAGE:4141743 /UG=Hs.25431 KIAA1219 protein BG236163 Ral GTPase activating protein, beta subunit (non-catalytic) RALGAPB 57148 NM_001282917 /// NM_001282918 /// NM_020336 /// XM_005260462 /// XM_005260463 /// XM_005260464 /// XM_005260465 0032484 // Ral protein signal transduction // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0017123 // Ral GTPase activator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 221739_at AL524093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL524093 /FEA=EST /DB_XREF=gi:12787586 /DB_XREF=est:AL524093 /CLONE=CS0DC002YI04 (5 prime) /UG=Hs.10927 hypothetical protein EUROIMAGE1875335 AL524093 chromosome 19 open reading frame 10 C19orf10 56005 NM_019107 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221740_x_at AI140364 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI140364 /FEA=EST /DB_XREF=gi:3647821 /DB_XREF=est:qa81h05.x1 /CLONE=IMAGE:1693209 /UG=Hs.190488 hypothetical protein FLJ10120 AI140364 Homo sapiens cDNA FLJ38031 fis, clone CTONG2013348. /// leucine rich repeat containing 37, member A2 DQ597730 /// LRRC37A2 474170 NM_001006607 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221741_s_at AL096828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL096828 /DEF=Human DNA sequence from clone RP5-963E22 on chromosome 20 Contains the 3 end of a novel gene similar to NY-REN-2 Antigen, 5 CpG islands, ESTs, STSs and GSSs /FEA=mRNA_2 /DB_XREF=gi:9663381 /UG=Hs.11747 hypothetical protein FLJ20391 AL096828 YTH domain family, member 1 YTHDF1 54915 NM_017798 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 1990247 // N6-methyladenosine-containing RNA binding // inferred from direct assay 221742_at BF037823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF037823 /FEA=EST /DB_XREF=gi:10746209 /DB_XREF=est:601461994F1 /CLONE=IMAGE:3865487 /UG=Hs.9683 DnaJ (Hsp40) homolog, subfamily C, member 3 BF037823 CUGBP, Elav-like family member 1 CELF1 10658 NM_001025596 /// NM_001172639 /// NM_001172640 /// NM_006560 /// NM_198700 /// XM_005252754 /// XM_005252755 /// XM_005252756 /// XM_006718122 /// XM_006718123 /// XM_006718124 /// XM_006718125 /// XM_006718126 /// XM_006718127 /// XM_006718128 /// XM_006718129 /// XM_006718130 /// XM_006718131 0006376 // mRNA splice site selection // inferred from sequence or structural similarity /// 0006397 // mRNA processing // traceable author statement /// 0007281 // germ cell development // non-traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016246 // RNA interference // non-traceable author statement /// 0017148 // negative regulation of translation // non-traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0042835 // BRE binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 221743_at AI472139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI472139 /FEA=EST /DB_XREF=gi:4334229 /DB_XREF=est:tj86a10.x1 /CLONE=IMAGE:2148378 /UG=Hs.9683 DnaJ (Hsp40) homolog, subfamily C, member 3 AI472139 CUGBP, Elav-like family member 1 CELF1 10658 NM_001025596 /// NM_001172639 /// NM_001172640 /// NM_006560 /// NM_198700 /// XM_005252754 /// XM_005252755 /// XM_005252756 /// XM_006718122 /// XM_006718123 /// XM_006718124 /// XM_006718125 /// XM_006718126 /// XM_006718127 /// XM_006718128 /// XM_006718129 /// XM_006718130 /// XM_006718131 0006376 // mRNA splice site selection // inferred from sequence or structural similarity /// 0006397 // mRNA processing // traceable author statement /// 0007281 // germ cell development // non-traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016246 // RNA interference // non-traceable author statement /// 0017148 // negative regulation of translation // non-traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0042835 // BRE binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 221744_at AK026008 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026008.1 /DEF=Homo sapiens cDNA: FLJ22355 fis, clone HRC06344. /FEA=mRNA /DB_XREF=gi:10438707 /UG=Hs.288283 Homo sapiens cDNA: FLJ22355 fis, clone HRC06344 AK026008 DDB1 and CUL4 associated factor 7 DCAF7 10238 NM_001003725 /// NM_005828 /// NR_073585 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221745_at BE538424 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE538424 /FEA=EST /DB_XREF=gi:9767069 /DB_XREF=est:601068256F1 /CLONE=IMAGE:3454693 /UG=Hs.288283 Homo sapiens cDNA: FLJ22355 fis, clone HRC06344 BE538424 DDB1 and CUL4 associated factor 7 DCAF7 10238 NM_001003725 /// NM_005828 /// NR_073585 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221746_at BE543027 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE543027 /FEA=EST /DB_XREF=gi:9771672 /DB_XREF=est:601068951F1 /CLONE=IMAGE:3455220 /UG=Hs.76480 ubiquitin-like 4 /FL=gb:NM_014235.1 BE543027 ubiquitin-like 4A UBL4A 8266 NM_014235 0006464 // cellular protein modification process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019787 // small conjugating protein ligase activity // traceable author statement 221747_at AL046979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046979 /FEA=EST /DB_XREF=gi:5435035 /DB_XREF=est:DKFZp586K0617_s1 /CLONE=DKFZp586K0617 /UG=Hs.9973 tensin AL046979 tensin 1 TNS1 7145 NM_022648 /// XM_005246825 /// XM_005246826 /// XM_006712721 /// XM_006712722 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221748_s_at AL046979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL046979 /FEA=EST /DB_XREF=gi:5435035 /DB_XREF=est:DKFZp586K0617_s1 /CLONE=DKFZp586K0617 /UG=Hs.9973 tensin AL046979 tensin 1 TNS1 7145 NM_022648 /// XM_005246825 /// XM_005246826 /// XM_006712721 /// XM_006712722 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221749_at AU157915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157915 /FEA=EST /DB_XREF=gi:11019436 /DB_XREF=est:AU157915 /CLONE=PLACE1010102 /UG=Hs.5518 Homo sapiens cDNA FLJ11311 fis, clone PLACE1010102 AU157915 YTH domain family, member 3 YTHDF3 253943 NM_001277813 /// NM_001277814 /// NM_001277815 /// NM_001277816 /// NM_001277817 /// NM_001277818 /// NM_152758 /// NR_102434 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 1990247 // N6-methyladenosine-containing RNA binding // inferred from direct assay 221750_at BG035985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG035985 /FEA=EST /DB_XREF=gi:12430666 /DB_XREF=est:602326096F1 /CLONE=IMAGE:4414319 /UG=Hs.77910 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) BG035985 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) HMGCS1 3157 NM_001098272 /// NM_002130 /// XM_005248295 0001101 // response to acid // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009645 // response to low light intensity stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014074 // response to purine-containing compound // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046690 // response to tellurium ion // inferred from electronic annotation /// 0055094 // response to lipoprotein particle // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004421 // hydroxymethylglutaryl-CoA synthase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043177 // organic acid binding // inferred from electronic annotation 221751_at AL565516 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565516 /FEA=EST /DB_XREF=gi:12916970 /DB_XREF=est:AL565516 /CLONE=CS0DF004YF08 (3 prime) /UG=Hs.6986 Human glucose transporter pseudogene AL565516 pantothenate kinase 3 PANK3 79646 NM_024594 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004594 // pantothenate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221752_at AL041728 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL041728 /FEA=EST /DB_XREF=gi:5421076 /DB_XREF=est:DKFZp434O0717_s1 /CLONE=DKFZp434O0717 /UG=Hs.60377 KIAA1298 protein AL041728 slingshot protein phosphatase 1 SSH1 54434 NM_001161330 /// NM_001161331 /// NM_018984 /// XM_005268984 /// XM_005268985 /// XM_005268986 /// XM_006719466 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0008064 // regulation of actin polymerization or depolymerization // not recorded /// 0010591 // regulation of lamellipodium assembly // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0032268 // regulation of cellular protein metabolic process // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded /// 0071318 // cellular response to ATP // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from mutant phenotype /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 221753_at AI651213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI651213 /FEA=EST /DB_XREF=gi:4735192 /DB_XREF=est:wa98a11.x1 /CLONE=IMAGE:2304188 /UG=Hs.60377 KIAA1298 protein AI651213 slingshot protein phosphatase 1 SSH1 54434 NM_001161330 /// NM_001161331 /// NM_018984 /// XM_005268984 /// XM_005268985 /// XM_005268986 /// XM_006719466 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0008064 // regulation of actin polymerization or depolymerization // not recorded /// 0010591 // regulation of lamellipodium assembly // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0032268 // regulation of cellular protein metabolic process // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded /// 0071318 // cellular response to ATP // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from mutant phenotype /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 221754_s_at AI341234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI341234 /FEA=EST /DB_XREF=gi:4078161 /DB_XREF=est:qx90b09.x1 /CLONE=IMAGE:2009753 /UG=Hs.6191 hypothetical protein DKFZp762I166 AI341234 coronin, actin binding protein, 1B CORO1B 57175 NM_001018070 /// NM_020441 0016477 // cell migration // inferred from direct assay /// 0030036 // actin cytoskeleton organization // not recorded /// 0031529 // ruffle organization // inferred from direct assay /// 0034316 // negative regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0090135 // actin filament branching // inferred from direct assay /// 1902463 // protein localization to cell leading edge // inferred from direct assay /// 2000394 // positive regulation of lamellipodium morphogenesis // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0030027 // lamellipodium // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0051015 // actin filament binding // not recorded /// 0051015 // actin filament binding // inferred from direct assay /// 0071933 // Arp2/3 complex binding // inferred from direct assay 221755_at BG334196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG334196 /FEA=EST /DB_XREF=gi:13140634 /DB_XREF=est:602461680F1 /CLONE=IMAGE:4578666 /UG=Hs.325852 Homo sapiens mRNA for FLJ00043 protein, partial cds BG334196 EH domain binding protein 1-like 1 EHBP1L1 254102 NM_001099409 /// XM_005273867 /// XM_005273868 /// XM_005273869 /// XM_005273870 /// XM_006718486 /// XM_006718487 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221756_at AL540260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL540260 /FEA=EST /DB_XREF=gi:12870241 /DB_XREF=est:AL540260 /CLONE=CS0DF032YF03 (3 prime) /UG=Hs.26670 Human PAC clone RP3-515N1 from 22q11.2-q22 AL540260 phosphoinositide-3-kinase interacting protein 1 PIK3IP1 113791 NM_001135911 /// NM_052880 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0043553 // negative regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043553 // negative regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0036313 // phosphatidylinositol 3-kinase catalytic subunit binding // inferred from physical interaction 221757_at BE042976 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE042976 /FEA=EST /DB_XREF=gi:8360029 /DB_XREF=est:ho31d03.x1 /CLONE=IMAGE:3038981 /UG=Hs.26670 Human PAC clone RP3-515N1 from 22q11.2-q22 BE042976 phosphoinositide-3-kinase interacting protein 1 PIK3IP1 113791 NM_001135911 /// NM_052880 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0043553 // negative regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043553 // negative regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0036313 // phosphatidylinositol 3-kinase catalytic subunit binding // inferred from physical interaction 221758_at BC003700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003700.1 /DEF=Homo sapiens, clone IMAGE:3461982, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3461982) /DB_XREF=gi:13277581 /UG=Hs.77876 Homo sapiens, clone IMAGE:3461982, mRNA, partial cds BC003700 armadillo repeat containing 6 ARMC6 93436 NM_001199196 /// NM_033415 /// XM_005260157 /// XM_005260158 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221759_at AL583123 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL583123 /FEA=EST /DB_XREF=gi:12951784 /DB_XREF=est:AL583123 /CLONE=CS0DL009YN09 (3 prime) /UG=Hs.294005 Homo sapiens, clone IMAGE:3050476, mRNA, partial cds AL583123 glucose 6 phosphatase, catalytic, 3 G6PC3 92579 NM_138387 /// NR_028581 /// NR_028582 /// XM_006722179 0005975 // carbohydrate metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004346 // glucose-6-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221760_at BG287153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG287153 /FEA=EST /DB_XREF=gi:13040709 /DB_XREF=est:602381868F1 /CLONE=IMAGE:4499393 /UG=Hs.25253 mannosidase, alpha, class 1A, member 1 BG287153 mannosidase, alpha, class 1A, member 1 MAN1A1 4121 NM_005907 /// XM_005266986 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 221761_at AA628948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA628948 /FEA=EST /DB_XREF=gi:2541335 /DB_XREF=est:af28f07.s1 /CLONE=IMAGE:1032997 /UG=Hs.90011 adenylosuccinate synthase /FL=gb:NM_001126.1 AA628948 adenylosuccinate synthase ADSS 159 NM_001126 0002376 // immune system process // non-traceable author statement /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006167 // AMP biosynthetic process // inferred from direct assay /// 0006167 // AMP biosynthetic process // non-traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006531 // aspartate metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0014074 // response to purine-containing compound // inferred from electronic annotation /// 0044208 // 'de novo' AMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046040 // IMP metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060359 // response to ammonium ion // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004019 // adenylosuccinate synthase activity // inferred from direct assay /// 0004019 // adenylosuccinate synthase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0042301 // phosphate ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 221762_s_at AL162458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL162458 /DEF=Human DNA sequence from clone RP11-465L10 on chromosome 20. Contains the gene for a novel protein similar to Drosophila CG11399, the gene for a novel C2H2 type zinc finger protein similar to chicken FZF-1, a Ferritin light polypeptide (FTL) pseudo... /FEA=mRNA_2 /DB_XREF=gi:9581599 /UG=Hs.272814 hypothetical protein DKFZp434E1723 AL162458 PDX1 C-terminal inhibiting factor 1 PCIF1 63935 NM_022104 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221763_at AI694023 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694023 /FEA=EST /DB_XREF=gi:4971363 /DB_XREF=est:wd13h03.x1 /CLONE=IMAGE:2328053 /UG=Hs.6685 thyroid hormone receptor interactor 8 AI694023 jumonji domain containing 1C JMJD1C 221037 NM_001282948 /// NM_004241 /// NM_032776 /// XM_005269622 /// XM_005269624 /// XM_005269626 /// XM_005269627 /// XM_005269628 /// XM_006717707 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 221764_at AL574186 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL574186 /FEA=EST /DB_XREF=gi:12934150 /DB_XREF=est:AL574186 /CLONE=CS0DI039YM09 (3 prime) /UG=Hs.9739 glycerol-3-phosphate dehydrogenase 1 (soluble) AL574186 R3H domain containing 4 R3HDM4 91300 NM_138774 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 221765_at AI378044 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI378044 /FEA=EST /DB_XREF=gi:4187897 /DB_XREF=est:te67h09.x1 /CLONE=IMAGE:2091809 /UG=Hs.23703 ESTs AI378044 UDP-glucose ceramide glucosyltransferase UGCG 7357 NM_003358 /// XM_005252186 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006679 // glucosylceramide biosynthetic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008120 // ceramide glucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 221766_s_at AW246673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW246673 /FEA=EST /DB_XREF=gi:6589666 /DB_XREF=est:2821951.3prime /CLONE=IMAGE:2821951 /UG=Hs.10784 hypothetical protein FLJ20037 AW246673 family with sequence similarity 46, member A FAM46A 55603 NM_017633 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype 0044822 // poly(A) RNA binding // inferred from direct assay 221767_x_at AA515560 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA515560 /FEA=EST /DB_XREF=gi:2255160 /DB_XREF=est:ni42c09.s1 /CLONE=IMAGE:979504 /UG=Hs.283473 hypothetical protein PRO2900 AA515560 high density lipoprotein binding protein HDLBP 3069 NM_001243900 /// NM_005336 /// NM_203346 /// XM_005247000 /// XM_005247001 /// XM_005247002 /// XM_005247003 /// XM_006712475 /// XM_006712476 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 221768_at AV705803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV705803 /FEA=EST /DB_XREF=gi:10723098 /DB_XREF=est:AV705803 /CLONE=ADBAFG09 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) AV705803 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221769_at AL571723 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL571723 /FEA=EST /DB_XREF=gi:12929303 /DB_XREF=est:AL571723 /CLONE=CS0DI031YD10 (3 prime) /UG=Hs.7247 ESTs, Weakly similar to TIE1_HUMAN TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 PRECURSOR H.sapiens AL571723 splA/ryanodine receptor domain and SOCS box containing 3 SPSB3 90864 NM_080861 /// XM_005255673 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221770_at BE964473 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE964473 /FEA=EST /DB_XREF=gi:11767942 /DB_XREF=est:601658180R1 /CLONE=IMAGE:3876354 /UG=Hs.125845 ribulose-5-phosphate-3-epimerase BE964473 ribulose-5-phosphate-3-epimerase RPE 6120 NM_001278282 /// NM_001278283 /// NM_001278285 /// NM_001278286 /// NM_001278288 /// NM_001278289 /// NM_006916 /// NM_199229 /// XM_006712677 0005975 // carbohydrate metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004750 // ribulose-phosphate 3-epimerase activity // not recorded /// 0004750 // ribulose-phosphate 3-epimerase activity // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from direct assay /// 0048029 // monosaccharide binding // inferred from electronic annotation 221771_s_at BC003542 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003542.1 /DEF=Homo sapiens, clone IMAGE:3611719, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3611719) /DB_XREF=gi:13097656 /UG=Hs.244482 Homo sapiens, clone IMAGE:3611719, mRNA, partial cds BC003542 M-phase phosphoprotein 8 MPHOSPH8 54737 NM_017520 /// XM_005266435 /// XM_005266436 /// XR_245390 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0044030 // regulation of DNA methylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype 0000788 // nuclear nucleosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 221772_s_at AI138993 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI138993 /FEA=EST /DB_XREF=gi:3644965 /DB_XREF=est:qd83e12.x1 /CLONE=IMAGE:1736110 /UG=Hs.85752 uncharacterized hematopoietic stemprogenitor cells protein MDS026 AI138993 protein phosphatase 2, regulatory subunit B, delta PPP2R2D 55844 NM_001003656 /// NM_001291310 /// NM_018461 /// NR_033191 /// XM_005277927 /// XM_006717914 /// XM_006717915 /// XR_428708 /// XR_428709 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity 221773_at AW575374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW575374 /FEA=EST /DB_XREF=gi:7246913 /DB_XREF=est:UI-HF-BL0-adc-c-12-0-UI.s1 /CLONE=IMAGE:3060887 /UG=Hs.288555 Homo sapiens cDNA: FLJ22425 fis, clone HRC08686 AW575374 ELK3, ETS-domain protein (SRF accessory protein 2) ELK3 2004 NM_005230 /// XM_006719275 0001525 // angiogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // not recorded /// 0042060 // wound healing // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032422 // purine-rich negative regulatory element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221774_x_at AW003334 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003334 /FEA=EST /DB_XREF=gi:5850250 /DB_XREF=est:wq65e08.x1 /CLONE=IMAGE:2476166 /UG=Hs.171185 transcription factor (p38 interacting protein) AW003334 suppressor of Ty 20 homolog (S. cerevisiae) SUPT20H 55578 NM_001014286 /// NM_001278480 /// NM_001278481 /// NM_001278482 /// NM_017569 /// XM_005266447 /// XM_005266448 /// XM_005266449 /// XM_005266450 /// XM_005266451 /// XM_005266452 /// XM_005266453 /// XM_005266454 /// XM_005266455 /// XM_005266456 /// XM_005266457 /// XM_005266458 /// XM_005266460 /// XM_005266461 /// XM_005266462 /// XM_005266464 /// XM_005266465 /// XM_005266466 /// XM_005266467 /// XM_005266468 0006325 // chromatin organization // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0000124 // SAGA complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221775_x_at BG152979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG152979 /FEA=EST /DB_XREF=gi:12665009 /DB_XREF=est:nah24c06.y1 /CLONE=IMAGE:4232050 /UG=Hs.99914 ribosomal protein L22 BG152979 ribosomal protein L22 RPL22 6146 NM_000983 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046632 // alpha-beta T cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221776_s_at AI885109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI885109 /FEA=EST /DB_XREF=gi:5590273 /DB_XREF=est:wl89g12.x1 /CLONE=IMAGE:2432134 /UG=Hs.279762 bromodomain-containing 7 AI885109 bromodomain containing 7 BRD7 29117 NM_001173984 /// NM_013263 /// XM_005255911 /// XM_005255912 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from direct assay /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // inferred from direct assay /// 0004016 // adenylate cyclase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 221777_at BE966197 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE966197 /FEA=EST /DB_XREF=gi:11771355 /DB_XREF=est:601660133R1 /CLONE=IMAGE:3905576 /UG=Hs.250820 Homo sapiens clone CDABP0113 mRNA sequence BE966197 RBPJ interacting and tubulin associated 1 RITA1 84934 NM_001286215 /// NM_032848 /// XM_005253972 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0051168 // nuclear export // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay 221778_at BE217882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE217882 /FEA=EST /DB_XREF=gi:8905200 /DB_XREF=est:hv31b02.x1 /CLONE=IMAGE:3174987 /UG=Hs.222707 KIAA1718 protein BE217882 lysine (K)-specific demethylase 7A KDM7A 80853 NM_030647 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0033169 // histone H3-K9 demethylation // inferred from direct assay /// 0035574 // histone H4-K20 demethylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay /// 0071557 // histone H3-K27 demethylation // inferred from direct assay 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005506 // iron ion binding // inferred from direct assay /// 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from direct assay /// 0032454 // histone demethylase activity (H3-K9 specific) // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0035575 // histone demethylase activity (H4-K20 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from direct assay 221779_at BC001090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC001090.1 /DEF=Homo sapiens, clone IMAGE:3504989, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3504989) /DB_XREF=gi:12654518 /UG=Hs.8535 hypothetical protein bA395L14.2 BC001090 MICAL-like 1 MICALL1 85377 NM_033386 /// XM_005261791 /// XM_005261792 /// XM_006724345 0006612 // protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from electronic annotation /// 0032458 // slow endocytic recycling // inferred from mutant phenotype /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0097320 // membrane tubulation // inferred from direct assay /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070300 // phosphatidic acid binding // inferred from direct assay 221780_s_at AF336851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF336851.1 /DEF=Homo sapiens RNA helicase-like protein (RHLP) mRNA, complete cds. /FEA=CDS /GEN=RHLP /PROD=RNA helicase-like protein /DB_XREF=gi:13384105 /UG=Hs.65234 hypothetical protein FLJ20596 /FL=gb:AF336851.1 AF336851 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 DDX27 55661 NM_017895 /// XM_006723815 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 221781_s_at BG168666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG168666 /FEA=EST /DB_XREF=gi:12675369 /DB_XREF=est:602319904F1 /CLONE=IMAGE:4415256 /UG=Hs.1098 DKFZp434J1813 protein BG168666 DnaJ (Hsp40) homolog, subfamily C, member 10 DNAJC10 54431 NM_001271581 /// NM_018981 /// NR_073365 /// NR_073366 /// NR_073367 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006304 // DNA modification // inferred from electronic annotation /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034975 // protein folding in endoplasmic reticulum // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0034663 // endoplasmic reticulum chaperone complex // inferred from direct assay 0001671 // ATPase activator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0003912 // DNA nucleotidylexotransferase activity // inferred from electronic annotation /// 0003912 // DNA nucleotidylexotransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0015035 // protein disulfide oxidoreductase activity // inferred from sequence or structural similarity /// 0015036 // disulfide oxidoreductase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 221782_at BG168666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG168666 /FEA=EST /DB_XREF=gi:12675369 /DB_XREF=est:602319904F1 /CLONE=IMAGE:4415256 /UG=Hs.1098 DKFZp434J1813 protein BG168666 DnaJ (Hsp40) homolog, subfamily C, member 10 DNAJC10 54431 NM_001271581 /// NM_018981 /// NR_073365 /// NR_073366 /// NR_073367 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from sequence or structural similarity /// 0034975 // protein folding in endoplasmic reticulum // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0034663 // endoplasmic reticulum chaperone complex // inferred from direct assay 0001671 // ATPase activator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0015035 // protein disulfide oxidoreductase activity // inferred from sequence or structural similarity /// 0015036 // disulfide oxidoreductase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from sequence or structural similarity /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 221783_at W67467 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W67467 /FEA=EST /DB_XREF=gi:1376338 /DB_XREF=est:zd43f11.r1 /CLONE=IMAGE:343437 /UG=Hs.193065 hypothetical protein DKFZp547M136 similar to widely-interspaced zinc finger motifs W67467 widely interspaced zinc finger motifs WIZ 58525 NM_021241 /// XM_005260004 /// XM_005260005 /// XM_005260006 /// XM_005260007 /// XM_005260008 /// XM_005260009 /// XM_005260010 /// XM_005260011 /// XM_005260012 /// XM_006722828 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0070208 // protein heterotrimerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221784_at AI089655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI089655 /FEA=EST /DB_XREF=gi:3428714 /DB_XREF=est:qb16h07.x1 /CLONE=IMAGE:1696477 /UG=Hs.193065 hypothetical protein DKFZp547M136 similar to widely-interspaced zinc finger motifs AI089655 widely interspaced zinc finger motifs WIZ 58525 NM_021241 /// XM_005260004 /// XM_005260005 /// XM_005260006 /// XM_005260007 /// XM_005260008 /// XM_005260009 /// XM_005260010 /// XM_005260011 /// XM_005260012 /// XM_006722828 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0070208 // protein heterotrimerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221785_at AI828531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI828531 /FEA=EST /DB_XREF=gi:5449202 /DB_XREF=est:wk30f03.x1 /CLONE=IMAGE:2413853 /UG=Hs.193065 hypothetical protein DKFZp547M136 similar to widely-interspaced zinc finger motifs AI828531 widely interspaced zinc finger motifs WIZ 58525 NM_021241 /// XM_005260004 /// XM_005260005 /// XM_005260006 /// XM_005260007 /// XM_005260008 /// XM_005260009 /// XM_005260010 /// XM_005260011 /// XM_005260012 /// XM_006722828 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0070208 // protein heterotrimerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221786_at BF197222 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF197222 /FEA=EST /DB_XREF=gi:11085906 /DB_XREF=est:7m88b07.x1 /CLONE=IMAGE:3561949 /UG=Hs.12342 Homo sapiens clone 24538 mRNA sequence BF197222 chromosome 6 open reading frame 120 C6orf120 387263 NM_001029863 0006915 // apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221787_at BF431618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF431618 /FEA=EST /DB_XREF=gi:11443732 /DB_XREF=est:7o16e03.x1 /CLONE=IMAGE:3574349 /UG=Hs.12342 Homo sapiens clone 24538 mRNA sequence BF431618 chromosome 6 open reading frame 120 C6orf120 387263 NM_001029863 0006915 // apoptotic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221788_at AV727934 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV727934 /FEA=EST /DB_XREF=gi:10837355 /DB_XREF=est:AV727934 /CLONE=HTCBWH07 /UG=Hs.237323 N-acetylglucosamine-phosphate mutase AV727934 phosphoglucomutase 3 PGM3 5238 NM_001199917 /// NM_001199918 /// NM_001199919 /// NM_015599 /// XM_005248728 /// XM_006715504 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006041 // glucosamine metabolic process // non-traceable author statement /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // not recorded /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019255 // glucose 1-phosphate metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // not recorded /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004610 // phosphoacetylglucosamine mutase activity // inferred from direct assay /// 0004614 // phosphoglucomutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221789_x_at AK024450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024450.1 /DEF=Homo sapiens mRNA for FLJ00042 protein, partial cds. /FEA=mRNA /GEN=FLJ00042 /PROD=FLJ00042 protein /DB_XREF=gi:10440413 /UG=Hs.21497 Homo sapiens, clone IMAGE:3629896, mRNA, partial cds AK024450 ras homolog family member T2 RHOT2 89941 NM_138769 /// XM_005255660 /// XM_005255661 /// XM_005255662 /// XM_005255663 /// XM_005255664 /// XM_006720970 /// XM_006720971 /// XM_006720972 /// XM_006720973 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from mutant phenotype /// 0047497 // mitochondrion transport along microtubule // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221790_s_at AL545035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL545035 /FEA=EST /DB_XREF=gi:12877516 /DB_XREF=est:AL545035 /CLONE=CS0DI013YH20 (3 prime) /UG=Hs.184482 DKFZP586D0624 protein AL545035 low density lipoprotein receptor adaptor protein 1 LDLRAP1 26119 NM_015627 /// XM_006710558 /// XM_006710559 /// XM_006710560 /// XM_006710561 /// XM_006710562 /// XR_426598 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0042982 // amyloid precursor protein metabolic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090118 // receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport // inferred from mutant phenotype /// 0090205 // positive regulation of cholesterol metabolic process // inferred by curator 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0030121 // AP-1 adaptor complex // inferred from direct assay /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0001784 // phosphotyrosine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from mutant phenotype /// 0030276 // clathrin binding // inferred from direct assay /// 0035591 // signaling adaptor activity // inferred from direct assay /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction 221791_s_at BG167522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG167522 /FEA=EST /DB_XREF=gi:12674151 /DB_XREF=est:602342728F1 /CLONE=IMAGE:4452895 /UG=Hs.171774 hypothetical protein BG167522 translation machinery associated 7 homolog (S. cerevisiae) TMA7 51372 NM_015933 221792_at AW118072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW118072 /FEA=EST /DB_XREF=gi:6086656 /DB_XREF=est:xe03a06.x1 /CLONE=IMAGE:2606002 /UG=Hs.89981 diacylglycerol kinase, zeta (104kD) AW118072 RAB6B, member RAS oncogene family RAB6B 51560 NM_016577 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // non-traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 221793_at BE531136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE531136 /FEA=EST /DB_XREF=gi:9759781 /DB_XREF=est:601278315F1 /CLONE=IMAGE:3610539 /UG=Hs.8982 ESTs, Highly similar to KIAA1395 protein H.sapiens BE531136 dedicator of cytokinesis 6 DOCK6 57572 NM_020812 /// XM_005260000 /// XM_005260001 /// XM_006722802 /// XM_006722803 /// XM_006722804 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 221794_at AI198543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI198543 /FEA=EST /DB_XREF=gi:3751149 /DB_XREF=est:qf49f11.x1 /CLONE=IMAGE:1753389 /UG=Hs.8982 ESTs, Highly similar to KIAA1395 protein H.sapiens AI198543 dedicator of cytokinesis 6 DOCK6 57572 NM_020812 /// XM_005260000 /// XM_005260001 /// XM_006722802 /// XM_006722803 /// XM_006722804 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 221795_at AI346341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI346341 /FEA=EST /DB_XREF=gi:4083547 /DB_XREF=est:qp50b09.x1 /CLONE=IMAGE:1926425 /UG=Hs.298998 Homo sapiens, Similar to hypothetical protein FLJ20093, clone MGC:1076, mRNA, complete cds AI346341 neurotrophic tyrosine kinase, receptor, type 2 NTRK2 4915 NM_001007097 /// NM_001018064 /// NM_001018065 /// NM_001018066 /// NM_001291937 /// NM_006180 /// XM_005252001 /// XM_005252003 /// XM_005252004 /// XM_005252006 /// XM_005252007 /// XM_006717120 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from electronic annotation /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043121 // neurotrophin binding // inferred from direct assay /// 0043121 // neurotrophin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0048403 // brain-derived neurotrophic factor binding // inferred from sequence or structural similarity /// 0060175 // brain-derived neurotrophic factor-activated receptor activity // inferred from mutant phenotype 221796_at AA707199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA707199 /FEA=EST /DB_XREF=gi:2717117 /DB_XREF=est:zj32g01.s1 /CLONE=IMAGE:452016 /UG=Hs.298998 Homo sapiens, Similar to hypothetical protein FLJ20093, clone MGC:1076, mRNA, complete cds AA707199 neurotrophic tyrosine kinase, receptor, type 2 NTRK2 4915 NM_001007097 /// NM_001018064 /// NM_001018065 /// NM_001018066 /// NM_001291937 /// NM_006180 /// XM_005252001 /// XM_005252003 /// XM_005252004 /// XM_005252006 /// XM_005252007 /// XM_006717120 0001570 // vasculogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0007631 // feeding behavior // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010996 // response to auditory stimulus // inferred from electronic annotation /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019222 // regulation of metabolic process // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from electronic annotation /// 0038179 // neurotrophin signaling pathway // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046928 // regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from sequence or structural similarity /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005030 // neurotrophin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043121 // neurotrophin binding // inferred from direct assay /// 0043121 // neurotrophin binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0048403 // brain-derived neurotrophic factor binding // inferred from sequence or structural similarity /// 0060175 // brain-derived neurotrophic factor-activated receptor activity // inferred from mutant phenotype 221797_at AY007126 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AY007126.1 /DEF=Homo sapiens clone CDABP0028 mRNA sequence. /FEA=mRNA /DB_XREF=gi:9956024 /UG=Hs.24435 Homo sapiens clone CDABP0028 mRNA sequence AY007126 oxidoreductase-like domain containing 1 OXLD1 339229 NM_001039842 0005739 // mitochondrion // inferred from electronic annotation 221798_x_at AI183766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI183766 /FEA=EST /DB_XREF=gi:3734404 /DB_XREF=est:qe17g06.x1 /CLONE=IMAGE:1739290 /UG=Hs.182426 ribosomal protein S2 AI183766 RP5-882O7.1 221799_at AB037823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037823.1 /DEF=Homo sapiens mRNA for KIAA1402 protein, partial cds. /FEA=mRNA /GEN=KIAA1402 /PROD=KIAA1402 protein /DB_XREF=gi:7243184 /UG=Hs.86392 KIAA1402 protein AB037823 chondroitin polymerizing factor 2 CHPF2 54480 NM_001284295 /// NM_019015 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation 221800_s_at AA551370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA551370 /FEA=EST /DB_XREF=gi:2321622 /DB_XREF=est:nk72f07.s1 /CLONE=IMAGE:1019077 /UG=Hs.289072 hypothetical protein FLJ22175 AA551370 chromosome 17 open reading frame 70 C17orf70 80233 NM_025161 /// NR_033338 /// XM_006722111 /// XM_006722112 /// XR_429925 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221801_x_at AL566528 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL566528 /FEA=EST /DB_XREF=gi:12918975 /DB_XREF=est:AL566528 /CLONE=CS0DF020YI15 (3 prime) /UG=Hs.211584 neurofilament, light polypeptide (68kD) /FL=gb:NM_006158.1 AL566528 neurofilament, light polypeptide NEFL 4747 NM_006158 0007268 // synaptic transmission // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from mutant phenotype /// 0008090 // retrograde axon cargo transport // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from mutant phenotype /// 0033693 // neurofilament bundle assembly // inferred from direct assay /// 0033693 // neurofilament bundle assembly // inferred from mutant phenotype /// 0045109 // intermediate filament organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0033596 // TSC1-TSC2 complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction 221802_s_at AU157109 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU157109 /FEA=EST /DB_XREF=gi:11018630 /DB_XREF=est:AU157109 /CLONE=PLACE1006159 /UG=Hs.23740 KIAA1598 protein AU157109 KIAA1598 KIAA1598 57698 NM_001127211 /// NM_001258298 /// NM_001258299 /// NM_001258300 /// NM_018330 /// XM_005270002 /// XM_006717931 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation 221803_s_at AA883074 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA883074 /FEA=EST /DB_XREF=gi:2992673 /DB_XREF=est:am18h01.s1 /CLONE=IMAGE:1467217 /UG=Hs.27181 nuclear receptor binding factor-2 AA883074 nuclear receptor binding factor 2 NRBF2 29982 NM_001282405 /// NM_030759 /// XM_006717810 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 221804_s_at BE565675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE565675 /FEA=EST /DB_XREF=gi:9809395 /DB_XREF=est:601338460F1 /CLONE=IMAGE:3680703 /UG=Hs.267923 uncharacterized hypothalamus protein HT011 BE565675 family with sequence similarity 45, member A /// family with sequence similarity 45, member A pseudogene FAM45A /// FAM45B 55855 /// 404636 NM_018472 /// NM_207009 /// NR_027141 /// XM_005269833 /// XM_006717849 /// XM_006717850 /// XM_006717851 /// XM_006717852 221805_at AL537457 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL537457 /FEA=EST /DB_XREF=gi:12800950 /DB_XREF=est:AL537457 /CLONE=CS0DF025YH07 (3 prime) /UG=Hs.211584 neurofilament, light polypeptide (68kD) /FL=gb:NM_006158.1 AL537457 neurofilament, light polypeptide NEFL 4747 NM_006158 0007268 // synaptic transmission // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from mutant phenotype /// 0008090 // retrograde axon cargo transport // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from mutant phenotype /// 0033693 // neurofilament bundle assembly // inferred from direct assay /// 0033693 // neurofilament bundle assembly // inferred from mutant phenotype /// 0045109 // intermediate filament organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0033596 // TSC1-TSC2 complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction 221806_s_at BF590997 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF590997 /FEA=EST /DB_XREF=gi:11683321 /DB_XREF=est:7h47c07.x1 /CLONE=IMAGE:3319116 /UG=Hs.7187 hypothetical protein FLJ10707 BF590997 SET domain containing 5 SETD5 55209 NM_001080517 /// NM_001292043 /// NM_018187 /// XM_005265299 /// XM_005265301 /// XM_005265303 /// XM_005265307 /// XM_006713235 /// XM_006713236 /// XM_006713237 /// XM_006713238 /// XM_006713239 /// XM_006713240 /// XM_006713241 /// XM_006713242 /// XM_006713243 /// XM_006713244 /// XM_006713245 0005515 // protein binding // inferred from electronic annotation 221807_s_at BG399562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG399562 /FEA=EST /DB_XREF=gi:13292929 /DB_XREF=est:602441852F1 /CLONE=IMAGE:4557732 /UG=Hs.33026 hypothetical protein PP2447 BG399562 TraB domain containing TRABD 80305 NM_025204 /// XM_006724419 /// XM_006724420 /// XM_006724421 /// XM_006724422 /// XM_006724423 /// XM_006724424 /// XM_006724425 /// XR_430480 /// XR_430481 /// XR_430482 221808_at NM_004251 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_004251.1 /DEF=Homo sapiens RAB9, member RAS oncogene family (RAB9), mRNA. /FEA=CDS /GEN=RAB9 /PROD=RAB9, member RAS oncogene family /DB_XREF=gi:4759011 /UG=Hs.28726 RAB9, member RAS oncogene family /FL=gb:U44103.1 gb:NM_004251.1 NM_004251 RAB9A, member RAS oncogene family RAB9A 9367 NM_001195328 /// NM_004251 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 221809_at AB040897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040897.1 /DEF=Homo sapiens mRNA for KIAA1464 protein, partial cds. /FEA=mRNA /GEN=KIAA1464 /PROD=KIAA1464 protein /DB_XREF=gi:7959188 /UG=Hs.6343 KIAA1464 protein AB040897 RAN binding protein 10 RANBP10 57610 NM_020850 /// XM_005256070 /// XM_005256072 /// XM_006721238 /// XM_006721239 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0032316 // regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 221810_at AA631242 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA631242 /FEA=EST /DB_XREF=gi:2553853 /DB_XREF=est:nq81b04.s1 /CLONE=IMAGE:1158703 /UG=Hs.21349 ESTs, Moderately similar to RB15 RAT RAS-RELATED PROTEIN RAB-15 R.norvegicus AA631242 RAB15, member RAS oncogene family RAB15 376267 NM_198686 /// XM_005267597 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 221811_at BF033007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF033007 /FEA=EST /DB_XREF=gi:10740719 /DB_XREF=est:601455980F1 /CLONE=IMAGE:3859819 /UG=Hs.91668 Homo sapiens clone PP1498 unknown mRNA BF033007 post-GPI attachment to proteins 3 PGAP3 93210 NM_001291726 /// NM_001291728 /// NM_001291730 /// NM_001291732 /// NM_001291733 /// NM_033419 0006505 // GPI anchor metabolic process // inferred from mutant phenotype /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from direct assay 0016788 // hydrolase activity, acting on ester bonds // inferred from mutant phenotype 221812_at AK025059 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025059.1 /DEF=Homo sapiens cDNA: FLJ21406 fis, clone COL03854. /FEA=mRNA /DB_XREF=gi:10437498 /UG=Hs.62767 KIAA1332 protein AK025059 F-box protein 42 FBXO42 54455 NM_018994 /// XM_006710698 0005515 // protein binding // inferred from electronic annotation 221813_at AI129395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI129395 /FEA=EST /DB_XREF=gi:3597909 /DB_XREF=est:qc38e05.x1 /CLONE=IMAGE:1711904 /UG=Hs.62767 KIAA1332 protein AI129395 F-box protein 42 FBXO42 54455 NM_018994 /// XM_006710698 0005515 // protein binding // inferred from electronic annotation 221814_at BF511315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511315 /FEA=EST /DB_XREF=gi:11594613 /DB_XREF=est:UI-H-BI4-aoj-h-02-0-UI.s1 /CLONE=IMAGE:3085275 /UG=Hs.17270 DKFZP434C211 protein BF511315 G protein-coupled receptor 124 GPR124 25960 NM_032777 /// XM_005273471 /// XM_006716325 0001525 // angiogenesis // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0010595 // positive regulation of endothelial cell migration // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0050920 // regulation of chemotaxis // inferred from sequence or structural similarity /// 0090210 // regulation of establishment of blood-brain barrier // inferred from electronic annotation /// 1900747 // negative regulation of vascular endothelial growth factor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221815_at BE671816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE671816 /FEA=EST /DB_XREF=gi:10032446 /DB_XREF=est:7a47d01.x1 /CLONE=IMAGE:3221857 /UG=Hs.21921 ESTs, Moderately similar to AF119917 63 PRO2831 H.sapiens BE671816 abhydrolase domain containing 2 ABHD2 11057 NM_007011 /// NM_152924 /// XM_005254832 /// XM_005254833 0008152 // metabolic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 221816_s_at BF055474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055474 /FEA=EST /DB_XREF=gi:10809370 /DB_XREF=est:7j80f07.x1 /CLONE=IMAGE:3392773 /UG=Hs.279799 putative zinc finger protein NY-REN-34 antigen BF055474 PHD finger protein 11 PHF11 51131 NM_001040443 /// NM_001040444 /// NM_016119 /// XM_005266417 /// XM_006719828 /// XM_006719829 /// XM_006719830 /// XM_006719831 /// XR_245387 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221817_at AI684664 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI684664 /FEA=EST /DB_XREF=gi:4895958 /DB_XREF=est:wa73b12.x1 /CLONE=IMAGE:2301791 /UG=Hs.21701 linked to Surfeit genes in Fugu rubripes 2; LSFR2 gene 2 AI684664 dolichyldiphosphatase 1 DOLPP1 57171 NM_001135917 /// NM_020438 /// NR_072983 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // not recorded /// 0006487 // protein N-linked glycosylation // inferred from sequence or structural similarity /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0008610 // lipid biosynthetic process // not recorded /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // not recorded /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047874 // dolichyldiphosphatase activity // not recorded /// 0047874 // dolichyldiphosphatase activity // inferred from sequence or structural similarity 221818_at BF446693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF446693 /FEA=EST /DB_XREF=gi:11511831 /DB_XREF=est:7q90g09.x1 /CLONE=IMAGE:3705785 /UG=Hs.6259 KIAA1698 protein BF446693 integrator complex subunit 5 INTS5 80789 NM_030628 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221819_at BF791960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF791960 /FEA=EST /DB_XREF=gi:12097014 /DB_XREF=est:602252342F1 /CLONE=IMAGE:4344539 /UG=Hs.94308 Homo sapiens cDNA FLJ10447 fis, clone NT2RP1000851 BF791960 RAB35, member RAS oncogene family RAB35 11021 NM_001167606 /// NM_006861 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031253 // cell projection membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 221820_s_at AK024102 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024102.1 /DEF=Homo sapiens cDNA FLJ14040 fis, clone HEMBA1005513, weakly similar to MALES-ABSENT ON THE FIRST PROTEIN (EC 2.3.1.-). /FEA=mRNA /DB_XREF=gi:10436399 /UG=Hs.42343 member of MYST family histone acetyl transferases, homolog of Drosophila MOF AK024102 K(lysine) acetyltransferase 8 KAT8 84148 NM_032188 /// NM_182958 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay /// 0072487 // MSL complex // inferred from direct assay 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 221821_s_at AK022732 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022732.1 /DEF=Homo sapiens cDNA FLJ12670 fis, clone NT2RM4002301. /FEA=mRNA /DB_XREF=gi:10434303 /UG=Hs.268189 hypothetical protein FLJ20436 AK022732 KAT8 regulatory NSL complex subunit 2 KANSL2 54934 NM_017822 0006325 // chromatin organization // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 221822_at BE544663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE544663 /FEA=EST /DB_XREF=gi:9773308 /DB_XREF=est:601074131F1 /CLONE=IMAGE:3460398 /UG=Hs.110407 ESTs, Weakly similar to coded for by C. elegans cDNA yk173c12.5 C.elegans BE544663 coiled-coil domain containing 101 CCDC101 112869 NM_138414 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0071169 // establishment of protein localization to chromatin // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 221823_at AL565741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL565741 /FEA=EST /DB_XREF=gi:12917418 /DB_XREF=est:AL565741 /CLONE=CS0DF007YN17 (3 prime) /UG=Hs.25925 Homo sapiens clone 23860 mRNA sequence AL565741 chromosome 5 open reading frame 30 C5orf30 90355 NM_033211 /// XM_005272123 /// XM_005272125 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221824_s_at AA770170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA770170 /FEA=EST /DB_XREF=gi:2821408 /DB_XREF=est:ah84d09.s1 /CLONE=1322321 /UG=Hs.288156 Homo sapiens cDNA: FLJ21819 fis, clone HEP01185 AA770170 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase MARCH8 220972 NM_001002265 /// NM_001002266 /// NM_001282866 /// NM_145021 /// XM_005271804 /// XM_006717704 /// XM_006717705 /// XR_246519 0000209 // protein polyubiquitination // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002495 // antigen processing and presentation of peptide antigen via MHC class II // inferred from electronic annotation /// 0006457 // protein folding // /// 0009306 // protein secretion // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // /// 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0003756 // protein disulfide isomerase activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042289 // MHC class II protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221825_at AU151793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151793 /FEA=EST /DB_XREF=gi:11013314 /DB_XREF=est:AU151793 /CLONE=NT2RP2006115 /UG=Hs.157078 Homo sapiens cDNA FLJ12793 fis, clone NT2RP2002033 AU151793 angel homolog 2 (Drosophila) ANGEL2 90806 NM_144567 /// XM_005273344 /// XM_005273345 /// XM_005273346 /// XM_005273347 /// XM_005273349 /// XM_006711616 /// XR_247045 221826_at BE671941 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE671941 /FEA=EST /DB_XREF=gi:10032405 /DB_XREF=est:7a46g02.x1 /CLONE=IMAGE:3221810 /UG=Hs.157078 Homo sapiens cDNA FLJ12793 fis, clone NT2RP2002033 BE671941 angel homolog 2 (Drosophila) ANGEL2 90806 NM_144567 /// XM_005273344 /// XM_005273345 /// XM_005273346 /// XM_005273347 /// XM_005273349 /// XM_006711616 /// XR_247045 221827_at BE788439 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE788439 /FEA=EST /DB_XREF=gi:10209637 /DB_XREF=est:601475616F1 /CLONE=IMAGE:3878643 /UG=Hs.247280 HBV associated factor BE788439 RanBP-type and C3HC4-type zinc finger containing 1 RBCK1 10616 NM_006462 /// NM_031227 /// NM_031228 /// NM_031229 /// XM_005260645 /// XM_005260646 /// XM_005260649 /// XR_430266 /// XR_430267 0000209 // protein polyubiquitination // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097039 // protein linear polyubiquitination // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0071797 // LUBAC complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221828_s_at AK024432 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024432.1 /DEF=Homo sapiens mRNA for FLJ00022 protein, partial cds. /FEA=mRNA /GEN=FLJ00022 /PROD=FLJ00022 protein /DB_XREF=gi:10440372 /UG=Hs.4914 Homo sapiens mRNA for FLJ00031 protein, partial cds AK024432 multivesicular body subunit 12B MVB12B 89853 NM_001011703 /// NM_033446 /// XM_005252297 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from mutant phenotype /// 0043130 // ubiquitin binding // inferred from direct assay 221829_s_at AI307759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI307759 /FEA=EST /DB_XREF=gi:4002363 /DB_XREF=est:tb24g08.x1 /CLONE=IMAGE:2055326 /UG=Hs.168075 karyopherin (importin) beta 2 AI307759 transportin 1 TNPO1 3842 NM_002270 /// NM_153188 /// XM_005248500 /// XM_005248501 0000060 // protein import into nucleus, translocation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221830_at AI302106 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI302106 /FEA=EST /DB_XREF=gi:3961452 /DB_XREF=est:qn57h10.x1 /CLONE=IMAGE:1902403 /UG=Hs.301746 RAP2A, member of RAS oncogene family /FL=gb:NM_021033.1 AI302106 RAP2A, member of RAS oncogene family RAP2A 5911 NM_021033 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0048814 // regulation of dendrite morphogenesis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 221831_at AV741657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV741657 /FEA=EST /DB_XREF=gi:10859238 /DB_XREF=est:AV741657 /CLONE=CBMALG01 /UG=Hs.154085 leucine zipper protein 1 AV741657 leucine zipper protein 1 LUZP1 7798 NM_001142546 /// NM_033631 0003281 // ventricular septum development // inferred from electronic annotation /// 0021503 // neural fold bending // inferred from electronic annotation /// 0060840 // artery development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 221832_s_at AV741657 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV741657 /FEA=EST /DB_XREF=gi:10859238 /DB_XREF=est:AV741657 /CLONE=CBMALG01 /UG=Hs.154085 leucine zipper protein 1 AV741657 leucine zipper protein 1 LUZP1 7798 NM_001142546 /// NM_033631 0003281 // ventricular septum development // inferred from electronic annotation /// 0021503 // neural fold bending // inferred from electronic annotation /// 0060840 // artery development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 221833_at AI971258 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI971258 /FEA=EST /DB_XREF=gi:5768084 /DB_XREF=est:wr27b08.x1 /CLONE=IMAGE:2488887 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 AI971258 uncharacterized LOC100507577 /// lon peptidase 2, peroxisomal /// siah E3 ubiquitin protein ligase 1 LOC100507577 /// LONP2 /// SIAH1 6477 /// 83752 /// 100507577 NM_001006610 /// NM_003031 /// NM_031490 /// NR_040677 /// XM_005256191 /// XM_006721246 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006515 // misfolded or incompletely synthesized protein catabolic process // not recorded /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221834_at AV700132 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700132 /FEA=EST /DB_XREF=gi:10302103 /DB_XREF=est:AV700132 /CLONE=GKCGSE03 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 AV700132 uncharacterized LOC100507577 /// lon peptidase 2, peroxisomal LOC100507577 /// LONP2 83752 /// 100507577 NM_031490 /// NR_040677 /// XM_005256191 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006465 // signal peptide processing // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // not recorded /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009295 // nucleoid // /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // /// 0046872 // metal ion binding // inferred from electronic annotation 221835_at N92708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N92708 /FEA=EST /DB_XREF=gi:1265017 /DB_XREF=est:zb44c04.s1 /CLONE=IMAGE:306438 /UG=Hs.32374 ESTs, Weakly similar to KIAA1528 protein H.sapiens N92708 deltex 3, E3 ubiquitin ligase DTX3 196403 NM_001286245 /// NM_001286246 /// NM_178502 /// XM_005268697 /// XM_005268698 /// XM_005268700 /// XM_005268703 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221836_s_at AW291218 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW291218 /FEA=EST /DB_XREF=gi:6697854 /DB_XREF=est:UI-H-BI2-agi-b-12-0-UI.s1 /CLONE=IMAGE:2724430 /UG=Hs.157240 Homo sapiens cDNA: FLJ22741 fis, clone HUV00774 AW291218 trafficking protein particle complex 9 TRAPPC9 83696 NM_001160372 /// NM_031466 /// XM_005251077 /// XM_006716664 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 221837_at BG325646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG325646 /FEA=EST /DB_XREF=gi:13132083 /DB_XREF=est:602424362F1 /CLONE=IMAGE:4562439 /UG=Hs.181341 Homo sapiens cDNA FLJ14307 fis, clone PLACE3000158 BG325646 kelch-like family member 22 KLHL22 84861 NM_032775 /// NR_033825 /// XM_006724342 /// XM_006724343 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221838_at N38751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N38751 /FEA=EST /DB_XREF=gi:1161958 /DB_XREF=est:yy42c07.s1 /CLONE=IMAGE:273900 /UG=Hs.181341 Homo sapiens cDNA FLJ14307 fis, clone PLACE3000158 N38751 kelch-like family member 22 KLHL22 84861 NM_032775 /// NR_033825 /// XM_006724342 /// XM_006724343 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221839_s_at AK026088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026088.1 /DEF=Homo sapiens cDNA: FLJ22435 fis, clone HRC09181. /FEA=mRNA /DB_XREF=gi:10438826 /UG=Hs.284247 KIAA1491 protein AK026088 ubiquitin associated protein 2 UBAP2 55833 NM_001282529 /// NM_001282530 /// NM_018449 /// NM_020867 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221840_at AA775177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA775177 /FEA=EST /DB_XREF=gi:2834511 /DB_XREF=est:ac79a06.s1 /CLONE=IMAGE:868786 /UG=Hs.31137 protein tyrosine phosphatase, receptor type, E /FL=gb:NM_006504.1 AA775177 protein tyrosine phosphatase, receptor type, E PTPRE 5791 NM_006504 /// NM_130435 /// XM_005252691 /// XM_005252692 /// XM_006717932 0006470 // protein dephosphorylation // traceable author statement /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 221841_s_at BF514079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF514079 /FEA=EST /DB_XREF=gi:11599258 /DB_XREF=est:UI-H-BW1-amw-b-08-0-UI.s1 /CLONE=IMAGE:3071198 /UG=Hs.7934 Kruppel-like factor 4 (gut) BF514079 Kruppel-like factor 4 (gut) KLF4 9314 NM_004235 /// XM_005252305 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007500 // mesodermal cell fate determination // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009913 // epidermal cell differentiation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014740 // negative regulation of muscle hyperplasia // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031077 // post-embryonic camera-type eye development // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0035166 // post-embryonic hemopoiesis // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045415 // negative regulation of interleukin-8 biosynthetic process // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045595 // regulation of cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046985 // positive regulation of hemoglobin biosynthetic process // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060761 // negative regulation of response to cytokine stimulus // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071409 // cellular response to cycloheximide // inferred from electronic annotation /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 1901653 // cellular response to peptide // inferred from electronic annotation /// 2000342 // negative regulation of chemokine (C-X-C motif) ligand 2 production // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001010 // sequence-specific DNA binding transcription factor recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221842_s_at BE972394 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE972394 /FEA=EST /DB_XREF=gi:10585730 /DB_XREF=est:601652210F1 /CLONE=IMAGE:3935546 /UG=Hs.78743 zinc finger protein 131 (clone pHZ-10) BE972394 uncharacterized LOC100506639 /// zinc finger protein 131 LOC100506639 /// ZNF131 7690 /// 100506639 NM_003432 /// NR_102752 /// XM_005248359 /// XM_005248360 /// XM_005248361 /// XM_005248362 /// XM_005248363 /// XM_005248365 /// XM_005248367 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221843_s_at AA195017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA195017 /FEA=EST /DB_XREF=gi:1784719 /DB_XREF=est:zr35c05.s1 /CLONE=IMAGE:665384 /UG=Hs.14449 KIAA1609 protein AA195017 TBC/LysM-associated domain containing 1 TLDC1 57707 NM_020947 /// XM_005256074 /// XM_005256075 /// XM_005256077 /// XM_006721240 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221844_x_at AV756161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV756161 /FEA=EST /DB_XREF=gi:10914009 /DB_XREF=est:AV756161 /CLONE=BMFBGA04 /UG=Hs.13323 hypothetical protein FLJ22059 AV756161 signal peptidase complex subunit 3 homolog (S. cerevisiae) SPCS3 60559 NM_021928 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 221845_s_at AI655698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI655698 /FEA=EST /DB_XREF=gi:4739677 /DB_XREF=est:tt14d09.x1 /CLONE=IMAGE:2240753 /UG=Hs.21263 suppressor of potassium transport defect 3 AI655698 ClpB caseinolytic peptidase B homolog (E. coli) CLPB 81570 NM_001258392 /// NM_001258393 /// NM_001258394 /// NM_030813 /// XM_005274320 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 221846_s_at AI970096 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI970096 /FEA=EST /DB_XREF=gi:5766922 /DB_XREF=est:wq89b02.x1 /CLONE=IMAGE:2479179 /UG=Hs.274408 KIAA1139 protein AI970096 CASK interacting protein 2 CASKIN2 57513 NM_001142643 /// NM_020753 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 221847_at BF665706 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF665706 /FEA=EST /DB_XREF=gi:11939601 /DB_XREF=est:602124033F1 /CLONE=IMAGE:4280744 /UG=Hs.45033 lacrimal proline rich protein BF665706 chromosome X open reading frame 69-like LOC100129361 100129361 NM_001271592 /// NR_036583 221848_at AL121845 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121845 /DEF=Human DNA sequence from clone RP4-583P15 on chromosome 20. Contains the 3 end of the TNFRSF6B gene for tumor necrosis factor receptor 6b (decoy), the gene for an ADP-ribosylation factor family protein, the gene for a novel protein with remote sim... /FEA=mRNA_25 /DB_XREF=gi:8246778 /UG=Hs.11900 Human DNA sequence from clone RP4-583P15 on chromosome 20. Contains the TNFRSF6B gene for tumor necrosis factor receptor 6b (decoy), the gene for an ADP-ribosylation factor family protein, the gene for a novel protein with remote similarity to C. elegans AL121845 zinc finger, CCCH-type with G patch domain ZGPAT 84619 NM_001083113 /// NM_001195653 /// NM_001195654 /// NM_032527 /// NM_181484 /// NM_181485 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221849_s_at AA733079 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA733079 /FEA=EST /DB_XREF=gi:2754438 /DB_XREF=est:zg79d12.s1 /CLONE=IMAGE:399575 /UG=Hs.298553 Homo sapiens, clone IMAGE:3953631, mRNA, partial cds AA733079 DDB1 and CUL4 associated factor 15 DCAF15 90379 NM_138353 0016567 // protein ubiquitination // inferred from electronic annotation 221850_x_at AI826075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI826075 /FEA=EST /DB_XREF=gi:5446746 /DB_XREF=est:wk28c04.x1 /CLONE=IMAGE:2413638 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 AI826075 ankyrin repeat and GTPase domain Arf GTPase activating protein 11 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene /// centaurin, gamma-like family, member 12 pseudogene /// arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4-like AGAP11 /// AGAP4 /// AGAP6 /// AGAP7P /// CTGLF12P /// LOC101060581 119016 /// 119385 /// 414189 /// 414224 /// 653268 /// 101060581 NM_001077665 /// NM_001077685 /// NM_001077686 /// NM_001276343 /// NM_001276344 /// NM_001291379 /// NM_133446 /// NM_133447 /// NR_029396 /// XM_005269836 /// XM_005269840 /// XM_005269841 /// XM_005271797 /// XM_005271800 /// XM_005276381 /// XM_005276382 /// XM_006717619 /// XM_006717620 /// XM_006717621 /// XM_006717622 /// XM_006717853 /// XM_006717854 /// XM_006717855 /// XM_006717856 /// XM_006717857 /// XM_006717858 /// XM_006717859 /// XM_006718092 /// XM_006726520 /// XR_432580 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221851_at AI073983 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI073983 /FEA=EST /DB_XREF=gi:3400627 /DB_XREF=est:oy66c04.x1 /CLONE=IMAGE:1670790 /UG=Hs.298553 Homo sapiens, clone IMAGE:3953631, mRNA, partial cds AI073983 DDB1 and CUL4 associated factor 15 DCAF15 90379 NM_138353 0016567 // protein ubiquitination // inferred from electronic annotation 221852_at N39536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N39536 /FEA=EST /DB_XREF=gi:1162743 /DB_XREF=est:yv27d07.s1 /CLONE=IMAGE:243949 /UG=Hs.322466 Homo sapiens cDNA: FLJ23491 fis, clone LNG00825, highly similar to HSPM5 Human mRNA for pM5 protein N39536 221853_s_at N39536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N39536 /FEA=EST /DB_XREF=gi:1162743 /DB_XREF=est:yv27d07.s1 /CLONE=IMAGE:243949 /UG=Hs.322466 Homo sapiens cDNA: FLJ23491 fis, clone LNG00825, highly similar to HSPM5 Human mRNA for pM5 protein N39536 uncharacterized LOC101060373 /// NODAL modulator 1 /// NODAL modulator 2 /// NODAL modulator 3 LOC101060373 /// NOMO1 /// NOMO2 /// NOMO3 23420 /// 283820 /// 408050 /// 101060373 NM_001004060 /// NM_001004067 /// NM_014287 /// NM_173614 /// XM_005255318 /// XM_006725195 /// XR_253508 /// XR_430727 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 221854_at AI378979 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI378979 /FEA=EST /DB_XREF=gi:4188832 /DB_XREF=est:tc40d07.x1 /CLONE=IMAGE:2067085 /UG=Hs.292911 ESTs AI378979 plakophilin 1 PKP1 5317 NM_000299 /// NM_001005337 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005882 // intermediate filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from direct assay /// 0019215 // intermediate filament binding // non-traceable author statement /// 0030280 // structural constituent of epidermis // non-traceable author statement 221855_at N31716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N31716 /FEA=EST /DB_XREF=gi:1152115 /DB_XREF=est:yy15c12.s1 /CLONE=IMAGE:271318 /UG=Hs.31754 ESTs N31716 succinate dehydrogenase complex assembly factor 1 SDHAF1 644096 NM_001042631 0016226 // iron-sulfur cluster assembly // non-traceable author statement /// 0034553 // mitochondrial respiratory chain complex II assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation 221856_s_at AL561943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL561943 /FEA=EST /DB_XREF=gi:12909874 /DB_XREF=est:AL561943 /CLONE=CS0DB002YO04 (3 prime) /UG=Hs.3346 hypothetical protein FLJ11280 AL561943 family with sequence similarity 63, member A FAM63A 55793 NM_001040217 /// NM_001163258 /// NM_001163259 /// NM_001163260 /// NM_018379 /// XM_005245320 /// XM_005245321 /// XM_005245322 /// XM_005245323 /// XM_005245325 /// XM_005245327 /// XM_005245328 /// XM_006711446 /// XM_006711447 /// XM_006711448 0070062 // extracellular vesicular exosome // inferred from direct assay 221857_s_at AK024269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024269.1 /DEF=Homo sapiens cDNA FLJ14207 fis, clone NT2RP3003185, weakly similar to TROPOMYOSIN 1, FUSION PROTEIN 33. /FEA=mRNA /DB_XREF=gi:10436606 /UG=Hs.9741 Homo sapiens cDNA FLJ14207 fis, clone NT2RP3003185, weakly similar to TROPOMYOSIN 1, FUSION PROTEIN 33 AK024269 tight junction associated protein 1 (peripheral) TJAP1 93643 NM_001146016 /// NM_001146017 /// NM_001146018 /// NM_001146019 /// NM_001146020 /// NM_080604 /// NR_027394 /// XM_006715249 /// XM_006715250 /// XM_006715251 /// XM_006715252 /// XM_006715253 /// XM_006715254 /// XM_006715255 /// XM_006715256 /// XM_006715257 /// XM_006715258 /// XM_006715259 /// XM_006715260 /// XM_006715261 /// XM_006715262 /// XM_006715263 /// XM_006715264 /// XM_006715265 /// XM_006715266 /// XM_006715267 /// XM_006715268 /// XM_006715269 /// XM_006715270 /// XM_006715271 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221858_at N34407 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N34407 /FEA=EST /DB_XREF=gi:1155549 /DB_XREF=est:yy53g10.s1 /CLONE=IMAGE:277314 /UG=Hs.100960 KIAA0608 protein N34407 TBC1 domain family, member 12 TBC1D12 23232 NM_015188 /// XM_006717732 /// XM_006717733 /// XR_246080 /// XR_428702 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 221859_at AW089736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW089736 /FEA=EST /DB_XREF=gi:6047080 /DB_XREF=est:xd11e07.x1 /CLONE=IMAGE:2593476 /UG=Hs.12365 synaptotagmin XIII AW089736 synaptotagmin XIII SYT13 57586 NM_001247987 /// NM_020826 /// XM_006718267 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 221860_at AL044078 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL044078 /FEA=EST /DB_XREF=gi:5935937 /DB_XREF=est:DKFZp434L2128_s1 /CLONE=DKFZp434L2128 /UG=Hs.2730 heterogeneous nuclear ribonucleoprotein L AL044078 221861_at AL157484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157484.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762M127 (from clone DKFZp762M127). /FEA=mRNA /DB_XREF=gi:7018527 /UG=Hs.22483 Homo sapiens mRNA; cDNA DKFZp762M127 (from clone DKFZp762M127) AL157484 arrestin, beta 1 ARRB1 408 NM_004041 /// NM_020251 /// XM_005273997 /// XM_005273998 /// XM_006718552 /// XM_006718553 /// XM_006718554 /// XM_006718555 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090240 // positive regulation of histone H4 acetylation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031143 // pseudopodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031896 // V2 vasopressin receptor binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 221862_at AB033019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB033019.1 /DEF=Homo sapiens mRNA for KIAA1193 protein, partial cds. /FEA=mRNA /GEN=KIAA1193 /PROD=KIAA1193 protein /DB_XREF=gi:6330357 /UG=Hs.101891 KIAA1193 protein AB033019 mesoderm induction early response 1, family member 2 MIER2 54531 NM_017550 /// XM_005259582 /// XM_006722769 /// XM_006722770 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 221863_at AW003889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003889 /FEA=EST /DB_XREF=gi:5850805 /DB_XREF=est:ws61f12.x1 /CLONE=IMAGE:2501711 /UG=Hs.101891 KIAA1193 protein AW003889 mesoderm induction early response 1, family member 2 MIER2 54531 NM_017550 /// XM_005259582 /// XM_006722769 /// XM_006722770 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 221864_at AW517464 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW517464 /FEA=EST /DB_XREF=gi:7155546 /DB_XREF=est:xp94g06.x1 /CLONE=IMAGE:2748058 /UG=Hs.119598 ribosomal protein L3 AW517464 ORAI calcium release-activated calcium modulator 3 ORAI3 93129 NM_152288 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221865_at BF969986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF969986 /FEA=EST /DB_XREF=gi:12337201 /DB_XREF=est:602272821F1 /CLONE=IMAGE:4360804 /UG=Hs.170226 Homo sapiens clone 23579 mRNA sequence BF969986 chromosome 9 open reading frame 91 C9orf91 203197 NM_153045 /// XM_005251789 /// XM_005251790 /// XM_005251791 /// XM_006716997 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221866_at AL035588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL035588 /DEF=Human DNA sequence from clone 696P19 on chromosome 6p12.3-21.2. Contains the gene for TFEB, an NPM1 (Nucleophosmin, Numatrin) pseudogene and the MDFI gene for MyoD family inhibitor (myogenic repressor I-MF). Contains ESTs, STSs, GSSs and two putat... /FEA=mRNA_2 /DB_XREF=gi:5419648 /UG=Hs.23391 Human DNA sequence from clone 696P19 on chromosome 6p12.3-21.2. Contains the gene for TFEB, an NPM1 (Nucleophosmin, Numatrin) pseudogene and the MDFI gene for MyoD family inhibitor (myogenic repressor I-MF). Contains ESTs, STSs, GSSs and two putative CpG AL035588 transcription factor EB TFEB 7942 NM_001167827 /// NM_001271943 /// NM_001271944 /// NM_001271945 /// NM_007162 /// XM_005249411 /// XM_005249412 /// XM_006715212 /// XM_006715213 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 221867_at BF436315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF436315 /FEA=EST /DB_XREF=gi:11448630 /DB_XREF=est:7p06b05.x1 /CLONE=IMAGE:3644888 /UG=Hs.296338 ESTs BF436315 NEDD4 binding protein 1 N4BP1 9683 NM_153029 /// XM_005256262 /// XM_006721351 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 221868_at AB032981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB032981.1 /DEF=Homo sapiens mRNA for KIAA1155 protein, partial cds. /FEA=mRNA /GEN=KIAA1155 /PROD=KIAA1155 protein /DB_XREF=gi:6330115 /UG=Hs.102657 KIAA1155 protein AB032981 poly(A) binding protein interacting protein 2B PAIP2B 400961 NM_020459 /// XM_005264310 /// XM_005264311 0045947 // negative regulation of translational initiation // inferred from direct assay 0005737 // cytoplasm // inferred by curator 0000900 // translation repressor activity, nucleic acid binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 221869_at AL118506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL118506 /DEF=Human DNA sequence from clone RP4-591C20 on chromosome 20. Contains ESTs, STSs, GSSs and CpG islands. Contains a novel gene for a protein similar to NG26, the TPD52L2 gene for two isoforms of tumor protein D52-like protein 2, a gene for a novel Dn... /FEA=mRNA_3 /DB_XREF=gi:10190557 /UG=Hs.158654 KIAA1196 protein AL118506 zinc finger protein 512B ZNF512B 57473 NM_020713 /// XM_005260226 /// XR_430305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221870_at AI417917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI417917 /FEA=EST /DB_XREF=gi:4261421 /DB_XREF=est:tg55d04.x1 /CLONE=IMAGE:2112679 /UG=Hs.20733 Homo sapiens cDNA: FLJ22356 fis, clone HRC06345 AI417917 EH-domain containing 2 EHD2 30846 NM_014601 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221871_s_at BF057492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF057492 /FEA=EST /DB_XREF=gi:10811388 /DB_XREF=est:7k44h01.x1 /CLONE=IMAGE:3478489 /UG=Hs.278572 anaplastic lymphoma kinase (Ki-1) BF057492 TRK-fused gene TFG 10342 NM_001007565 /// NM_001195478 /// NM_001195479 /// NM_006070 /// XM_005247066 /// XM_006713472 /// XM_006713473 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005737 // cytoplasm // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 221872_at AI669229 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI669229 /FEA=EST /DB_XREF=gi:4834003 /DB_XREF=est:wc13e06.x1 /CLONE=IMAGE:2315074 /UG=Hs.82547 retinoic acid receptor responder (tazarotene induced) 1 AI669229 retinoic acid receptor responder (tazarotene induced) 1 RARRES1 5918 NM_002888 /// NM_206963 /// XM_005247686 0008285 // negative regulation of cell proliferation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 221873_at AW162015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW162015 /FEA=EST /DB_XREF=gi:6301048 /DB_XREF=est:au72d09.x1 /CLONE=IMAGE:2781809 /UG=Hs.154095 zinc finger protein 143 (clone pHZ-1) AW162015 zinc finger protein 143 ZNF143 7702 NM_001282656 /// NM_001282657 /// NM_003442 /// XM_005253121 /// XM_005253122 /// XM_005253126 /// XM_005253127 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 221874_at AB037745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037745.1 /DEF=Homo sapiens mRNA for KIAA1324 protein, partial cds. /FEA=mRNA /GEN=KIAA1324 /PROD=KIAA1324 protein /DB_XREF=gi:7243028 /UG=Hs.104696 KIAA1324 protein AB037745 KIAA1324 KIAA1324 57535 NM_001267048 /// NM_001267049 /// NM_001284352 /// NM_001284353 /// NM_020775 0006914 // autophagy // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0044090 // positive regulation of vacuole organization // inferred from mutant phenotype /// 2000786 // positive regulation of autophagic vacuole assembly // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 221875_x_at AW514210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514210 /FEA=EST /DB_XREF=gi:7152378 /DB_XREF=est:hd75b05.x1 /CLONE=IMAGE:2915313 /UG=Hs.110309 major histocompatibility complex, class I, F AW514210 major histocompatibility complex, class I, F HLA-F 3134 NM_001098478 /// NM_001098479 /// NM_018950 /// XM_005249054 /// XM_005272809 /// XM_005274960 /// XM_005275115 /// XM_005275390 /// XM_005275547 /// XM_005275548 /// XM_006726089 /// XM_006726090 /// XM_006726091 /// XM_006726092 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // not recorded /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // inferred from physical interaction 221876_at AU151157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU151157 /FEA=EST /DB_XREF=gi:11012678 /DB_XREF=est:AU151157 /CLONE=NT2RP2004523 /UG=Hs.14217 hypothetical protein DKFZp762P2111 AU151157 zinc finger family member 783 ZNF783 100289678 NM_001195220 /// XM_005249929 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221877_at BF508835 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508835 /FEA=EST /DB_XREF=gi:11592133 /DB_XREF=est:UI-H-BI4-aor-d-03-0-UI.s1 /CLONE=IMAGE:3085853 /UG=Hs.6217 Homo sapiens cDNA FLJ12521 fis, clone NT2RM2001840 BF508835 immunity-related GTPase family, Q IRGQ 126298 NM_001007561 /// XM_005258515 /// XM_005258516 221878_at BF110411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110411 /FEA=EST /DB_XREF=gi:10940101 /DB_XREF=est:7n52f02.x1 /CLONE=IMAGE:3568274 /UG=Hs.16959 ESTs BF110411 chromosome 2 open reading frame 68 C2orf68 388969 NM_001013649 /// XM_005264304 /// XM_005264305 /// XM_005264306 221879_at AA886335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA886335 /FEA=EST /DB_XREF=gi:3001443 /DB_XREF=est:oj23g02.s1 /CLONE=IMAGE:1493042 /UG=Hs.239812 Homo sapiens serologically defined breast cancer antigen NY-BR-20 mRNA, partial cds AA886335 calmodulin-like 4 CALML4 91860 NM_001031733 /// NM_001286694 /// NM_001286695 /// NM_033429 /// NR_104583 0005509 // calcium ion binding // inferred from electronic annotation 221880_s_at AI279819 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI279819 /FEA=EST /DB_XREF=gi:3918053 /DB_XREF=est:qm26h04.x1 /CLONE=IMAGE:1882999 /UG=Hs.27373 Homo sapiens mRNA; cDNA DKFZp564O1763 (from clone DKFZp564O1763) AI279819 family with sequence similarity 174, member B FAM174B 400451 NM_207446 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221881_s_at AI638420 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI638420 /FEA=EST /DB_XREF=gi:4690654 /DB_XREF=est:tt31g07.x1 /CLONE=IMAGE:2242428 /UG=Hs.25035 chloride intracellular channel 4 AI638420 chloride intracellular channel 4 CLIC4 25932 NM_013943 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // non-traceable author statement /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 221882_s_at AI636233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI636233 /FEA=EST /DB_XREF=gi:4687563 /DB_XREF=est:tz93b07.x1 /CLONE=IMAGE:2296117 /UG=Hs.288940 five-span transmembrane protein M83 AI636233 transmembrane protein 8A TMEM8A 58986 NM_021259 0006412 // translation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 221883_at AA133342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA133342 /FEA=EST /DB_XREF=gi:1690310 /DB_XREF=est:zn92h03.s1 /CLONE=IMAGE:565685 /UG=Hs.6700 ESTs AA133342 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 221884_at BE466525 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE466525 /FEA=EST /DB_XREF=gi:9512223 /DB_XREF=est:hx94b10.x1 /CLONE=IMAGE:3195451 /UG=Hs.234773 Homo sapiens cDNA: FLJ22281 fis, clone HRC03849, highly similar to S69002 human mRNA for AML1-EVI-1 BE466525 MDS1 and EVI1 complex locus MECOM 2122 NM_001105077 /// NM_001105078 /// NM_001163999 /// NM_001164000 /// NM_001205194 /// NM_004991 /// NM_005241 /// XM_005247213 /// XM_005247214 /// XM_005247215 /// XM_005247216 /// XM_005247219 /// XM_005247220 /// XM_005247221 /// XM_005247223 /// XM_005247224 /// XM_005247225 /// XM_005247226 /// XM_006713536 /// XM_006713537 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030900 // forebrain development // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060039 // pericardium development // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 0072001 // renal system development // inferred from electronic annotation /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 221885_at AI131051 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI131051 /FEA=EST /DB_XREF=gi:3601067 /DB_XREF=est:qb82h09.x1 /CLONE=IMAGE:1706657 /UG=Hs.6385 KIAA1277 protein AI131051 DENN/MADD domain containing 2A DENND2A 27147 NM_015689 /// XM_005249976 /// XM_005249977 /// XM_005249978 /// XM_005249979 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 221886_at AL037701 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL037701 /FEA=EST /DB_XREF=gi:5928273 /DB_XREF=est:DKFZp564P1672_s1 /CLONE=DKFZp564P1672 /UG=Hs.6385 KIAA1277 protein AL037701 DENN/MADD domain containing 2A DENND2A 27147 NM_015689 /// XM_005249976 /// XM_005249977 /// XM_005249978 /// XM_005249979 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 221887_s_at BE045998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE045998 /FEA=EST /DB_XREF=gi:8363051 /DB_XREF=est:hd91d02.x4 /CLONE=IMAGE:2916867 /UG=Hs.93836 DKFZP434N014 protein BE045998 deafness, autosomal recessive 31 DFNB31 25861 NM_001083885 /// NM_001173425 /// NM_015404 /// XM_005251895 /// XM_005251897 /// XM_005251898 /// XM_006717041 0001895 // retina homeostasis // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0060122 // inner ear receptor stereocilium organization // inferred from sequence or structural similarity 0002142 // stereocilia ankle link complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221888_at AW183030 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW183030 /FEA=EST /DB_XREF=gi:6451490 /DB_XREF=est:xj66a04.x1 /CLONE=IMAGE:2662158 /UG=Hs.181780 hypothetical protein FLJ20241 AW183030 coiled-coil and C2 domain containing 1A CC2D1A 54862 NM_017721 /// XM_005259972 /// XM_005259973 /// XM_005259974 /// XM_005259975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 221889_at AW026481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW026481 /FEA=EST /DB_XREF=gi:5880011 /DB_XREF=est:wv14a04.x1 /CLONE=IMAGE:2529486 /UG=Hs.48396 ESTs, Moderately similar to A41784 tumor necrosis factor-alpha-induced protein B12 H.sapiens AW026481 potassium channel tetramerization domain containing 13 KCTD13 253980 NM_178863 /// NR_110933 0006260 // DNA replication // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 221890_at NM_022095 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_022095.1 /DEF=Homo sapiens hypothetical C2H2 zinc finger protein FLJ22504 (FLJ22504), mRNA. /FEA=CDS /GEN=FLJ22504 /PROD=hypothetical C2H2 zinc finger protein FLJ22504 /DB_XREF=gi:11560151 /UG=Hs.165983 hypothetical C2H2 zinc finger protein FLJ22504 /FL=gb:NM_022095.1 NM_022095 zinc finger protein 335 ZNF335 63925 NM_022095 /// XM_005260504 /// XM_005260506 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221891_x_at AA704004 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA704004 /FEA=EST /DB_XREF=gi:2713922 /DB_XREF=est:ag46h11.s1 /CLONE=IMAGE:1119909 /UG=Hs.180414 heat shock 70kD protein 8 AA704004 heat shock 70kDa protein 8 /// small nucleolar RNA, C/D box 14C /// small nucleolar RNA, C/D box 14D HSPA8 /// SNORD14C /// SNORD14D 3312 /// 85389 /// 85390 NM_006597 /// NM_153201 /// NR_001453 /// NR_001454 /// XM_006718831 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042026 // protein refolding // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1902904 // negative regulation of fibril organization // inferred from direct assay 0000974 // Prp19 complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 221892_at AK024548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024548.1 /DEF=Homo sapiens cDNA: FLJ20895 fis, clone ADKA03483. /FEA=mRNA /DB_XREF=gi:10436853 /UG=Hs.285737 Homo sapiens cDNA: FLJ20895 fis, clone ADKA03483 AK024548 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) H6PD 9563 NM_001282587 /// NM_004285 /// XM_005263539 /// XM_005263540 /// XM_005263541 /// XM_006711052 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006739 // NADP metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097305 // response to alcohol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017057 // 6-phosphogluconolactonase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0047936 // glucose 1-dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 221893_s_at N32831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32831 /FEA=EST /DB_XREF=gi:1153230 /DB_XREF=est:yw85g05.s1 /CLONE=IMAGE:259064 /UG=Hs.27262 Homo sapiens clone 25110 mRNA sequence N32831 aarF domain containing kinase 2 ADCK2 90956 NM_052853 /// XM_006716170 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221894_at N32831 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N32831 /FEA=EST /DB_XREF=gi:1153230 /DB_XREF=est:yw85g05.s1 /CLONE=IMAGE:259064 /UG=Hs.27262 Homo sapiens clone 25110 mRNA sequence N32831 aarF domain containing kinase 2 ADCK2 90956 NM_052853 /// XM_006716170 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221895_at AW469184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW469184 /FEA=EST /DB_XREF=gi:7039290 /DB_XREF=est:hc78g04.x1 /CLONE=IMAGE:2898870 /UG=Hs.65406 ESTs AW469184 motile sperm domain containing 2 MOSPD2 158747 NM_001177475 /// NM_152581 /// XM_005274451 /// XM_006724467 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 221896_s_at BE739519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE739519 /FEA=EST /DB_XREF=gi:10153511 /DB_XREF=est:601556450T1 /CLONE=IMAGE:3826141 /UG=Hs.7917 DKFZP564K247 protein BE739519 HIG1 hypoxia inducible domain family, member 1A HIGD1A 25994 NM_001099668 /// NM_001099669 /// NM_014056 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 221897_at AA205660 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA205660 /FEA=EST /DB_XREF=gi:1803652 /DB_XREF=est:zq68g08.s1 /CLONE=IMAGE:646814 /UG=Hs.94037 hypothetical protein FLJ23053 AA205660 tripartite motif containing 52 TRIM52 84851 NM_032765 /// XM_005266000 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221898_at AU154455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU154455 /FEA=EST /DB_XREF=gi:11015976 /DB_XREF=est:AU154455 /CLONE=NT2RP4001145 /UG=Hs.135150 lung type-I cell membrane-associated glycoprotein AU154455 podoplanin PDPN 10630 NM_001006624 /// NM_001006625 /// NM_006474 /// NM_198389 /// XM_006710295 0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001946 // lymphangiogenesis // inferred from sequence or structural similarity /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0006833 // water transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from sequence or structural similarity /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010572 // positive regulation of platelet activation // inferred from electronic annotation /// 0015884 // folic acid transport // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035239 // tube morphogenesis // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from sequence or structural similarity /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0001726 // ruffle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005372 // water transmembrane transporter activity // inferred from sequence or structural similarity /// 0008517 // folic acid transporter activity // inferred from sequence or structural similarity /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015250 // water channel activity // inferred from sequence or structural similarity 221899_at AI809961 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI809961 /FEA=EST /DB_XREF=gi:5396527 /DB_XREF=est:wf64b09.x1 /CLONE=IMAGE:2360345 /UG=Hs.23518 hypothetical protein from BCRA2 region AI809961 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 221900_at AI806793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI806793 /FEA=EST /DB_XREF=gi:5393359 /DB_XREF=est:wf15d05.x1 /CLONE=IMAGE:2350665 /UG=Hs.249239 collagen, type VIII, alpha 2 AI806793 collagen, type VIII, alpha 2 COL8A2 1296 NM_001294347 /// NM_005202 /// XM_005270477 /// XM_005270478 /// XM_005270479 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 221901_at BF516072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF516072 /FEA=EST /DB_XREF=gi:11601251 /DB_XREF=est:UI-H-BW1-anx-a-12-0-UI.s1 /CLONE=IMAGE:3083806 /UG=Hs.6829 Homo sapiens mRNA for KIAA1644 protein, partial cds BF516072 KIAA1644 KIAA1644 85352 NM_001099294 /// XM_005261790 /// XM_006724344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221902_at AL567940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL567940 /FEA=EST /DB_XREF=gi:12921802 /DB_XREF=est:AL567940 /CLONE=CS0DF036YK19 (3 prime) /UG=Hs.7967 ESTs AL567940 G protein-coupled receptor 153 GPR153 387509 NM_207370 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 221903_s_at BE046443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE046443 /FEA=EST /DB_XREF=gi:8363496 /DB_XREF=est:hn47d10.x2 /CLONE=IMAGE:3026803 /UG=Hs.18827 KIAA0849 protein BE046443 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 221904_at AI141670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI141670 /FEA=EST /DB_XREF=gi:3649127 /DB_XREF=est:ot08b12.x1 /CLONE=IMAGE:1614239 /UG=Hs.141660 chloride channel 2 AI141670 family with sequence similarity 131, member A FAM131A 131408 NM_001171093 /// NM_144635 /// XM_005247113 /// XM_005247114 /// XM_005247115 0005576 // extracellular region // inferred from electronic annotation 221905_at BF516433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF516433 /FEA=EST /DB_XREF=gi:11601612 /DB_XREF=est:UI-H-BW1-aoc-a-03-0-UI.s1 /CLONE=IMAGE:3084173 /UG=Hs.18827 KIAA0849 protein BF516433 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 221906_at BF513089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF513089 /FEA=EST /DB_XREF=gi:11598268 /DB_XREF=est:UI-H-BW1-amn-d-07-0-UI.s1 /CLONE=IMAGE:3070501 /UG=Hs.20030 Homo sapiens thioredoxin reductase 3 (TRXR3) mRNA, partial cds BF513089 thioredoxin reductase 3 /// thioredoxin reductase 3 neighbor TXNRD3 /// TXNRD3NB 114112 /// 645840 NM_001039783 /// NM_001173513 /// NM_052883 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045454 // cell redox homeostasis // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004791 // thioredoxin-disulfide reductase activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 221907_at AI679213 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI679213 /FEA=EST /DB_XREF=gi:4889395 /DB_XREF=est:tu72g04.x1 /CLONE=IMAGE:2256630 /UG=Hs.81920 ESTs, Weakly similar to cDNA EST yk213d3.5 comes from this gene C.elegans AI679213 tRNA methyltransferase 61 homolog A (S. cerevisiae) TRMT61A 115708 NM_152307 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0031515 // tRNA (m1A) methyltransferase complex // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016429 // tRNA (adenine-N1-)-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221908_at AL120375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL120375 /FEA=EST /DB_XREF=gi:5926274 /DB_XREF=est:DKFZp761C088_s1 /CLONE=DKFZp761C088 /UG=Hs.18653 ESTs AL120375 ring finger protein, transmembrane 2 RNFT2 84900 NM_001109903 /// NM_032814 /// XM_005253968 /// XM_005253969 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 221909_at AW299700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW299700 /FEA=EST /DB_XREF=gi:6709377 /DB_XREF=est:xs42g04.x1 /CLONE=IMAGE:2772342 /UG=Hs.18653 ESTs AW299700 ring finger protein, transmembrane 2 RNFT2 84900 NM_001109903 /// NM_032814 /// XM_005253968 /// XM_005253969 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221910_at BF131965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF131965 /FEA=EST /DB_XREF=gi:10971005 /DB_XREF=est:601820946F1 /CLONE=IMAGE:4052867 /UG=Hs.10684 Homo sapiens clone 24421 mRNA sequence BF131965 ets variant 1 ETV1 2115 NM_001163147 /// NM_001163148 /// NM_001163149 /// NM_001163150 /// NM_001163151 /// NM_001163152 /// NM_004956 /// NR_120445 /// XM_005249635 /// XM_005249636 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // traceable author statement 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221911_at BE881590 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE881590 /FEA=EST /DB_XREF=gi:10330366 /DB_XREF=est:601490008F1 /CLONE=IMAGE:3892465 /UG=Hs.10684 Homo sapiens clone 24421 mRNA sequence BE881590 ets variant 1 ETV1 2115 NM_001163147 /// NM_001163148 /// NM_001163149 /// NM_001163150 /// NM_001163151 /// NM_001163152 /// NM_004956 /// NR_120445 /// XM_005249635 /// XM_005249636 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007638 // mechanosensory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048935 // peripheral nervous system neuron development // traceable author statement 0005634 // nucleus // not recorded 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221912_s_at AL049795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL049795 /DEF=Human DNA sequence from clone RP4-622L5 on chromosome 1p34.2-36.11. Contains the gene for importin alpha 7 (karyopherin), up to six novel genes and the 5 end of the EIF3S2 gene for eukaryotic translation initiation factor 3 beta. Contains ESTs, S... /FEA=mRNA_8 /DB_XREF=gi:6010175 /UG=Hs.17987 hypothetical protein MGC1203 AL049795 coiled-coil domain containing 28B CCDC28B 79140 NM_024296 /// XM_006710892 /// XM_006710893 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 221913_at AI492888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI492888 /FEA=EST /DB_XREF=gi:4393891 /DB_XREF=est:th78c09.x1 /CLONE=IMAGE:2124784 /UG=Hs.19306 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3 AI492888 sirtuin 3 SIRT3 23410 NM_001017524 /// NM_012239 /// XM_005252835 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 221914_at H19843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H19843 /FEA=EST /DB_XREF=gi:888538 /DB_XREF=est:yn57c12.s1 /CLONE=IMAGE:172534 /UG=Hs.225936 synapsin I /FL=gb:NM_006950.1 H19843 synapsin I SYN1 6853 NM_006950 /// NM_133499 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation 221915_s_at AI221318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI221318 /FEA=EST /DB_XREF=gi:3803521 /DB_XREF=est:qg74h09.x1 /CLONE=IMAGE:1840961 /UG=Hs.24763 RAN binding protein 1 AI221318 RAN binding protein 1 RANBP1 5902 NM_001278639 /// NM_001278640 /// NM_001278641 /// NM_002882 /// XM_006724287 /// XM_006724288 0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement 221916_at BF055311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF055311 /FEA=EST /DB_XREF=gi:10809207 /DB_XREF=est:7j78a07.x1 /CLONE=IMAGE:3392532 /UG=Hs.302689 hypothetical protein BF055311 neurofilament, light polypeptide NEFL 4747 NM_006158 0007268 // synaptic transmission // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from mutant phenotype /// 0008090 // retrograde axon cargo transport // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from mutant phenotype /// 0033693 // neurofilament bundle assembly // inferred from direct assay /// 0033693 // neurofilament bundle assembly // inferred from mutant phenotype /// 0045109 // intermediate filament organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0033596 // TSC1-TSC2 complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction 221917_s_at BF058465 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF058465 /FEA=EST /DB_XREF=gi:10812361 /DB_XREF=est:7k31a05.x1 /CLONE=IMAGE:3477008 /UG=Hs.79295 G-rich RNA sequence binding factor 1 BF058465 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 221918_at AI742210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742210 /FEA=EST /DB_XREF=gi:5110498 /DB_XREF=est:wg39c02.x1 /CLONE=IMAGE:2367458 /UG=Hs.183302 ESTs AI742210 cyclin-dependent kinase 17 CDK17 5128 NM_001170464 /// NM_002595 /// XM_006719444 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 221919_at AW450929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450929 /FEA=EST /DB_XREF=gi:6991705 /DB_XREF=est:UI-H-BI3-all-f-08-0-UI.s1 /CLONE=IMAGE:2737287 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 AW450929 heterogeneous nuclear ribonucleoprotein A1 HNRNPA1 3178 NM_002136 /// NM_031157 /// XM_005268826 /// XR_245923 /// XR_245924 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221920_s_at BE677761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE677761 /FEA=EST /DB_XREF=gi:10038376 /DB_XREF=est:7f59h05.x1 /CLONE=IMAGE:3299001 /UG=Hs.300496 mitochondrial solute carrier BE677761 solute carrier family 25 (mitochondrial iron transporter), member 37 SLC25A37 51312 NM_016612 /// XM_005273526 /// XM_006716352 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048250 // mitochondrial iron ion transport // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation 221921_s_at AI951798 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI951798 /FEA=EST /DB_XREF=gi:5744108 /DB_XREF=est:wx37f11.x1 /CLONE=IMAGE:2545869 /UG=Hs.6164 hypothetical protein FLJ10698 /FL=gb:NM_021189.1 AI951798 cell adhesion molecule 3 CADM3 57863 NM_001127173 /// NM_021189 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 221922_at AW195581 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW195581 /FEA=EST /DB_XREF=gi:6474731 /DB_XREF=est:xn84d08.x1 /CLONE=IMAGE:2701167 /UG=Hs.93121 KIAA0761 protein AW195581 G-protein signaling modulator 2 GPSM2 29899 NM_013296 /// XM_005270787 /// XM_006710588 /// XM_006710589 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 221923_s_at AA191576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA191576 /FEA=EST /DB_XREF=gi:1780275 /DB_XREF=est:zp81c10.s1 /CLONE=IMAGE:626610 /UG=Hs.9614 nucleophosmin (nucleolar phosphoprotein B23, numatrin) AA191576 nucleophosmin (nucleolar phosphoprotein B23, numatrin) NPM1 4869 NM_001037738 /// NM_002520 /// NM_199185 /// XM_005265920 /// XM_006714869 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 221924_at AW444969 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW444969 /FEA=EST /DB_XREF=gi:6986731 /DB_XREF=est:UI-H-BI3-aka-b-07-0-UI.s1 /CLONE=IMAGE:2733636 /UG=Hs.77978 Homo sapiens mRNA; cDNA DKFZp761I2123 (from clone DKFZp761I2123); complete cds AW444969 zinc finger, MIZ-type containing 2 ZMIZ2 83637 NM_031449 /// NM_174929 /// XM_005249866 /// XM_005249867 /// XM_005249868 /// XM_005249869 /// XM_005249870 /// XM_005249871 /// XM_005249872 /// XM_005249873 /// XM_005249874 /// XM_005249875 /// XM_006715787 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043596 // nuclear replication fork // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 221925_s_at BE044503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE044503 /FEA=EST /DB_XREF=gi:8361556 /DB_XREF=est:ho46d12.x1 /CLONE=IMAGE:3040439 /UG=Hs.153746 hypothetical protein FLJ22490 BE044503 centrosome and spindle pole associated protein 1 CSPP1 79848 NM_001077204 /// NM_001291339 /// NM_024790 /// XM_005251305 /// XM_005251306 /// XM_005251307 /// XM_005251311 /// XM_006716469 /// XM_006716470 /// XM_006716471 /// XM_006716472 /// XM_006716473 /// XM_006716474 /// XM_006716475 /// XM_006716476 /// XM_006716477 /// XM_006716478 /// XM_006716479 /// XM_006716480 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051781 // positive regulation of cell division // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221926_s_at BF196320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF196320 /FEA=EST /DB_XREF=gi:11084137 /DB_XREF=est:7n68c09.x1 /CLONE=IMAGE:3569680 /UG=Hs.129959 ESTs, Weakly similar to IL-17 receptor H.sapiens BF196320 interleukin 17 receptor C IL17RC 84818 NM_001203263 /// NM_001203264 /// NM_001203265 /// NM_032732 /// NM_153460 /// NM_153461 /// NM_153462 /// NM_153463 /// NR_037807 /// XM_006713346 /// XM_006713347 /// XM_006713348 /// XM_006713349 /// XM_006713350 /// XM_006713351 /// XM_006713352 /// XM_006713353 /// XM_006713354 /// XM_006713355 /// XM_006713356 /// XM_006713357 /// XM_006713358 /// XM_006713359 /// XM_006713360 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030368 // interleukin-17 receptor activity // inferred from direct assay 221927_s_at AI923458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI923458 /FEA=EST /DB_XREF=gi:5659422 /DB_XREF=est:wn85h04.x1 /CLONE=IMAGE:2452663 /UG=Hs.182476 Homo sapiens clone PP1226 unknown mRNA AI923458 abhydrolase domain containing 11 ABHD11 83451 NM_001145363 /// NM_001145364 /// NM_148912 /// NM_148913 /// NM_148914 /// NM_148916 /// NR_026910 /// NR_026912 /// XM_006716143 /// XM_006716144 /// XM_006716145 /// XR_428186 0006505 // GPI anchor metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 221928_at AI057637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI057637 /FEA=EST /DB_XREF=gi:3331503 /DB_XREF=est:oy31h06.x1 /CLONE=IMAGE:1667483 /UG=Hs.234898 ESTs, Weakly similar to 2109260A B cell growth factor H.sapiens AI057637 acetyl-CoA carboxylase beta ACACB 32 NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098 0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221929_at BG149837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG149837 /FEA=EST /DB_XREF=gi:12661867 /DB_XREF=est:nae01b12.x1 /CLONE=IMAGE:3434062 /UG=Hs.33540 ESTs, Weakly similar to dJ309K20.4 H.sapiens BG149837 RP11-10N23.4 221930_at AI217472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI217472 /FEA=EST /DB_XREF=gi:3797287 /DB_XREF=est:qh15b07.x1 /CLONE=IMAGE:1844725 /UG=Hs.30127 hypothetical protein AI217472 PHD finger protein 7 PHF7 51533 NM_001278221 /// NM_016483 /// NM_173341 /// XM_005265225 /// XM_005265226 /// XM_005265227 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation 221931_s_at AV701173 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV701173 /FEA=EST /DB_XREF=gi:10717503 /DB_XREF=est:AV701173 /CLONE=ADAAGH04 /UG=Hs.301048 Homo sapiens sec13-like protein mRNA, complete cds AV701173 SEH1-like (S. cerevisiae) SEH1L 81929 NM_001013437 /// NM_031216 /// XM_005258152 /// XM_005258153 /// XM_006722359 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007080 // mitotic metaphase plate congression // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051315 // attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 221932_s_at AA133341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA133341 /FEA=EST /DB_XREF=gi:1690309 /DB_XREF=est:zn92h02.s1 /CLONE=IMAGE:565683 /UG=Hs.13201 clone FLB4739 AA133341 glutaredoxin 5 GLRX5 51218 NM_016417 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation 221933_at AI338338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI338338 /FEA=EST /DB_XREF=gi:4075265 /DB_XREF=est:qq96f07.x1 /CLONE=IMAGE:1939237 /UG=Hs.21107 neuroligin AI338338 neuroligin 4, X-linked NLGN4X 57502 NM_001282145 /// NM_001282146 /// NM_020742 /// NM_181332 /// XM_005274564 /// XM_005274565 /// XM_005274566 /// XM_005274568 /// XM_006724504 0003360 // brainstem development // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // traceable author statement /// 0007612 // learning // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // non-traceable author statement /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0045216 // cell-cell junction organization // non-traceable author statement /// 0046622 // positive regulation of organ growth // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from mutant phenotype /// 0050808 // synapse organization // non-traceable author statement /// 0071625 // vocalization behavior // inferred from mutant phenotype /// 0071625 // vocalization behavior // inferred from sequence or structural similarity /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from direct assay /// 0097105 // presynaptic membrane assembly // inferred from direct assay 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0045202 // synapse // not recorded /// 0045202 // synapse // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from direct assay 0004872 // receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from direct assay /// 0042043 // neurexin family protein binding // inferred from direct assay /// 0042043 // neurexin family protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0050839 // cell adhesion molecule binding // traceable author statement 221934_s_at BF941492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF941492 /FEA=EST /DB_XREF=gi:12358812 /DB_XREF=est:nac74d09.x1 /CLONE=IMAGE:3439937 /UG=Hs.280978 hypothetical protein FLJ10496 BF941492 DALR anticodon binding domain containing 3 DALRD3 55152 NM_001009996 /// NM_001276405 /// NM_018114 /// XM_005265266 /// XM_005265267 /// XM_005265269 /// XM_005265270 /// XM_005265272 /// XM_005265274 /// XM_006713218 /// XM_006713219 /// XR_245144 /// XR_245146 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 221935_s_at AK023140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023140.1 /DEF=Homo sapiens cDNA FLJ13078 fis, clone NT2RP3002002. /FEA=mRNA /DB_XREF=gi:10434924 /UG=Hs.5997 hypothetical protein FLJ13078 AK023140 EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase EOGT 285203 NM_001278689 /// NM_173654 /// NR_103826 /// XM_005264743 /// XM_005264744 /// XM_006713111 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0016262 // protein N-acetylglucosaminyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 221936_x_at AI090841 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI090841 /FEA=EST /DB_XREF=gi:3429900 /DB_XREF=est:ov44e04.x1 /CLONE=IMAGE:1640190 /UG=Hs.44017 sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2 AI090841 mitochondrial ribosomal protein L41 MRPL41 64975 NM_032477 0006412 // translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221937_at AI472320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI472320 /FEA=EST /DB_XREF=gi:4334410 /DB_XREF=est:tj87c02.x1 /CLONE=IMAGE:2148482 /UG=Hs.48504 ESTs, Moderately similar to ALU5_HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI472320 synergin, gamma SYNRG 11276 NM_001163544 /// NM_001163545 /// NM_001163546 /// NM_001163547 /// NM_007247 /// NM_080550 /// NM_198882 /// XM_005256980 /// XM_005256981 /// XM_005256982 /// XM_005256983 /// XM_005256985 /// XM_005256986 /// XM_005256988 /// XM_006721652 /// XM_006721653 /// XM_006721654 /// XM_006721655 /// XM_006725301 /// XM_006725302 /// XM_006725303 /// XM_006725304 /// XM_006725305 /// XM_006725306 /// XM_006725307 /// XM_006725308 /// XM_006725309 /// XM_006725310 /// XM_006725311 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 221938_x_at AW262690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW262690 /FEA=EST /DB_XREF=gi:6639506 /DB_XREF=est:xq93d08.x1 /CLONE=IMAGE:2758191 /UG=Hs.31659 thyroid hormone receptor-associated protein, 95-kD subunit AW262690 mediator complex subunit 16 MED16 10025 NM_005481 /// XM_006722600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from direct assay /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 221939_at AL529396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL529396 /FEA=EST /DB_XREF=gi:12792889 /DB_XREF=est:AL529396 /CLONE=CS0DD006YI03 (3 prime) /UG=Hs.143696 coactivator-associated arginine methyltransferase-1 AL529396 Yip1 domain family, member 2 YIPF2 78992 NM_024029 /// XM_005260069 /// XM_005260070 /// XM_005260071 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 221940_at AI571208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI571208 /FEA=EST /DB_XREF=gi:4534582 /DB_XREF=est:tn43d09.x1 /CLONE=IMAGE:2170385 /UG=Hs.173311 C18B11 homolog (44.9kD) AI571208 RNA pseudouridylate synthase domain containing 2 RPUSD2 27079 NM_001286407 /// NM_152260 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 221941_at BE646315 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE646315 /FEA=EST /DB_XREF=gi:9970626 /DB_XREF=est:7e84f08.x1 /CLONE=IMAGE:3289191 /UG=Hs.292503 ESTs, Weakly similar to T47142 hypothetical protein DKFZp761P0724.1 H.sapiens BE646315 polyamine oxidase (exo-N4-amino) PAOX 196743 NM_152911 /// NM_207125 /// NM_207126 /// NM_207127 /// NM_207128 /// NM_207129 /// NR_109763 /// NR_109764 /// NR_109765 /// NR_109766 0006184 // GTP catabolic process // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008215 // spermine metabolic process // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from direct assay /// 0009447 // putrescine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042254 // ribosome biogenesis // /// 0044065 // regulation of respiratory system process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046203 // spermidine catabolic process // inferred from direct assay /// 0046208 // spermine catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070129 // regulation of mitochondrial translation // inferred from mutant phenotype /// 1901307 // positive regulation of spermidine biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // /// 0003924 // GTPase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046592 // polyamine oxidase activity // inferred from direct assay /// 0052899 // N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052901 // spermine:oxygen oxidoreductase (spermidine-forming) activity // inferred from electronic annotation /// 0052902 // spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity // inferred from electronic annotation /// 0052903 // N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052904 // N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // traceable author statement 221942_s_at AI719730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI719730 /FEA=EST /DB_XREF=gi:5036986 /DB_XREF=est:as92b12.x1 /CLONE=IMAGE:2353055 /UG=Hs.306079 sec61 homolog AI719730 guanylate cyclase 1, soluble, alpha 3 GUCY1A3 2982 NM_000856 /// NM_001130682 /// NM_001130683 /// NM_001130684 /// NM_001130685 /// NM_001130686 /// NM_001130687 /// NM_001256449 /// XM_005262955 /// XM_005262956 /// XM_005262957 /// XM_006714196 /// XM_006714197 /// XM_006714198 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0052565 // response to defense-related host nitric oxide production // inferred from electronic annotation /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0008074 // guanylate cyclase complex, soluble // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 221943_x_at AW303136 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW303136 /FEA=EST /DB_XREF=gi:6712816 /DB_XREF=est:xr59c08.x1 /CLONE=IMAGE:2764430 /UG=Hs.2017 ribosomal protein L38 AW303136 ribosomal protein L38 RPL38 6169 NM_000999 /// NM_001035258 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034463 // 90S preribosome assembly // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048318 // axial mesoderm development // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0033291 // eukaryotic 80S initiation complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 221944_at N56912 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N56912 /FEA=EST /DB_XREF=gi:1200802 /DB_XREF=est:yy82b06.s1 /CLONE=IMAGE:280019 /UG=Hs.1074 surfactant, pulmonary-associated protein C N56912 uncharacterized LOC645644 FLJ42627 645644 NR_024492 221945_at AA906578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA906578 /FEA=EST /DB_XREF=gi:3042164 /DB_XREF=est:ol22c06.s1 /CLONE=IMAGE:1524202 /UG=Hs.23158 ESTs AA906578 F-box protein 41 /// uncharacterized LOC101927826 FBXO41 /// LOC101927826 150726 /// 101927826 NM_001080410 /// XM_005264158 /// XM_006711950 /// XR_245023 /// XR_245024 /// XR_249149 /// XR_249150 /// XR_251093 /// XR_251094 0005515 // protein binding // inferred from electronic annotation 221946_at AU160041 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU160041 /FEA=EST /DB_XREF=gi:11021562 /DB_XREF=est:AU160041 /CLONE=Y79AA1000969 /UG=Hs.120858 Homo sapiens cDNA FLJ13945 fis, clone Y79AA1000969 AU160041 chromosome 9 open reading frame 116 C9orf116 138162 NM_001048265 /// NM_144654 221947_at BF112057 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF112057 /FEA=EST /DB_XREF=gi:10941670 /DB_XREF=est:7l38b08.x1 /CLONE=IMAGE:3523550 /UG=Hs.129959 ESTs, Weakly similar to IL-17 receptor H.sapiens BF112057 221948_s_at BF732879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF732879 /FEA=EST /DB_XREF=gi:12057954 /DB_XREF=est:nae16g06.x1 /CLONE=IMAGE:3435467 /UG=Hs.181341 Homo sapiens cDNA FLJ14307 fis, clone PLACE3000158 BF732879 kelch-like family member 22 KLHL22 84861 NM_032775 /// NR_033825 /// XM_006724342 /// XM_006724343 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005827 // polar microtubule // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221949_at AW006953 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006953 /FEA=EST /DB_XREF=gi:5855731 /DB_XREF=est:wt08d06.x1 /CLONE=IMAGE:2506859 /UG=Hs.237946 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW006953 ubiquitin-conjugating enzyme E2D 4 (putative) UBE2D4 51619 NM_015983 /// XM_005249772 /// XM_006715734 /// XM_006715735 /// XM_006715736 /// XM_006715737 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 221950_at AI478455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478455 /FEA=EST /DB_XREF=gi:4371681 /DB_XREF=est:tm44c06.x1 /CLONE=IMAGE:2160970 /UG=Hs.202095 empty spiracles (Drosophila) homolog 2 AI478455 empty spiracles homeobox 2 EMX2 2018 NM_001165924 /// NM_004098 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021796 // cerebral cortex regionalization // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021885 // forebrain cell migration // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 221951_at AI739035 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI739035 /FEA=EST /DB_XREF=gi:5101016 /DB_XREF=est:wi34e04.x1 /CLONE=IMAGE:2392158 /UG=Hs.28974 ESTs AI739035 transmembrane protein 80 TMEM80 283232 NM_001042463 /// NM_001042464 /// NM_001276253 /// NM_001276274 /// NM_174940 /// XM_006718206 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221952_x_at AB037814 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037814.1 /DEF=Homo sapiens mRNA for KIAA1393 protein, partial cds. /FEA=mRNA /GEN=KIAA1393 /PROD=KIAA1393 protein /DB_XREF=gi:7243166 /UG=Hs.33317 KIAA1393 protein AB037814 tRNA methyltransferase 5 TRMT5 57570 NM_020810 /// XM_005267916 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0009019 // tRNA (guanine-N1-)-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052906 // tRNA (guanine(37)-N(1))-methyltransferase activity // inferred from electronic annotation 221953_s_at W45551 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W45551 /FEA=EST /DB_XREF=gi:1329632 /DB_XREF=est:zc26d02.s1 /CLONE=IMAGE:323427 /UG=Hs.3743 matrix metalloproteinase 24 (membrane-inserted) W45551 MMP24 antisense RNA 1 MMP24-AS1 101410538 NR_102705 /// NR_102706 221954_at AA160474 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA160474 /FEA=EST /DB_XREF=gi:1735971 /DB_XREF=est:zq49a10.s1 /CLONE=IMAGE:633018 /UG=Hs.75798 hypothetical protein AA160474 oxidative stress responsive serine-rich 1 OSER1 51526 NM_016470 /// XM_005260424 /// XM_005260425 /// XM_006723803 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation 221955_at AI040021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI040021 /FEA=EST /DB_XREF=gi:3279215 /DB_XREF=est:ox97g03.x1 /CLONE=IMAGE:1664308 /UG=Hs.1686 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) AI040021 221956_at AI631881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI631881 /FEA=EST /DB_XREF=gi:4683211 /DB_XREF=est:wa37c06.x1 /CLONE=IMAGE:2300266 /UG=Hs.125742 leucine-rich neuronal protein AI631881 leucine-rich repeats and calponin homology (CH) domain containing 4 LRCH4 4034 NM_001289934 /// NM_002319 /// XM_005250346 /// XM_005250347 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 221957_at BF939522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF939522 /FEA=EST /DB_XREF=gi:12356842 /DB_XREF=est:nac77g06.x1 /CLONE=IMAGE:3440458 /UG=Hs.193124 pyruvate dehydrogenase kinase, isoenzyme 3 BF939522 pyruvate dehydrogenase kinase, isozyme 3 PDK3 5165 NM_001142386 /// NM_005391 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from mutant phenotype /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071398 // cellular response to fatty acid // inferred from mutant phenotype /// 0097411 // hypoxia-inducible factor-1alpha signaling pathway // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 221958_s_at AA775681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA775681 /FEA=EST /DB_XREF=gi:2835015 /DB_XREF=est:zf31a02.s1 /CLONE=IMAGE:378506 /UG=Hs.250746 hypothetical protein FLJ23091 AA775681 wntless Wnt ligand secretion mediator WLS 79971 NM_001002292 /// NM_001193334 /// NM_024911 0001707 // mesoderm formation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0031937 // positive regulation of chromatin silencing // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from electronic annotation 221959_at BE672313 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE672313 /FEA=EST /DB_XREF=gi:10032854 /DB_XREF=est:7a59b10.x1 /CLONE=IMAGE:3223003 /UG=Hs.34054 Homo sapiens cDNA: FLJ22488 fis, clone HRC10948, highly similar to HSU79298 Human clone 23803 mRNA BE672313 family with sequence similarity 110, member B FAM110B 90362 NM_147189 /// XM_005251324 /// XM_005251325 /// XM_005251326 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 221960_s_at AI189609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI189609 /FEA=EST /DB_XREF=gi:3740818 /DB_XREF=est:qd32g02.x1 /CLONE=IMAGE:1725458 /UG=Hs.78305 RAB2, member RAS oncogene family AI189609 RAB2A, member RAS oncogene family RAB2A 5862 NM_001242644 /// NM_002865 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 221961_at AW190208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW190208 /FEA=EST /DB_XREF=gi:6464688 /DB_XREF=est:xl60a12.x1 /CLONE=IMAGE:2679070 /UG=Hs.233789 ESTs AW190208 chloride channel, voltage-sensitive 7 CLCN7 1186 NM_001114331 /// NM_001287 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 221962_s_at AI829920 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI829920 /FEA=EST /DB_XREF=gi:5450591 /DB_XREF=est:wj47d11.x1 /CLONE=IMAGE:2405973 /UG=Hs.28505 ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8) AI829920 ubiquitin-conjugating enzyme E2H UBE2H 7328 NM_001202498 /// NM_003344 /// NM_182697 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 221963_x_at BE999967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE999967 /FEA=EST /DB_XREF=gi:10700243 /DB_XREF=est:7h15a06.x1 /CLONE=IMAGE:3316018 /UG=Hs.87409 thrombospondin 1 BE999967 zinc finger protein 587B ZNF587B 100293516 NM_001204818 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221964_at AI591305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI591305 /FEA=EST /DB_XREF=gi:4600353 /DB_XREF=est:tw11e09.x1 /CLONE=IMAGE:2259400 /UG=Hs.39706 ESTs AI591305 tubby like protein 3 TULP3 7289 NM_001160408 /// NM_003324 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021914 // negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021953 // central nervous system neuron differentiation // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from direct assay /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0060434 // bronchus morphogenesis // inferred from electronic annotation /// 0060831 // smoothened signaling pathway involved in dorsal/ventral neural tube patterning // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030991 // intraciliary transport particle A // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0072372 // primary cilium // inferred from direct assay /// 0097546 // ciliary base // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 221965_at AI990326 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI990326 /FEA=EST /DB_XREF=gi:5837207 /DB_XREF=est:ws39d06.x1 /CLONE=IMAGE:2499563 /UG=Hs.86178 M-phase phosphoprotein 9 AI990326 221966_at AA813194 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA813194 /FEA=EST /DB_XREF=gi:2883179 /DB_XREF=est:ai80g12.s1 /CLONE=1377190 /UG=Hs.25274 chromosome 11 hypothetical protein ORF4 AA813194 G protein-coupled receptor 137 GPR137 56834 NM_001170726 /// NM_001170880 /// NM_001170881 /// NM_001177358 /// NM_020155 /// XM_005274100 /// XM_005274101 /// XM_005274102 /// XM_005274104 /// XM_006718636 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221967_at AI933199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI933199 /FEA=EST /DB_XREF=gi:5671936 /DB_XREF=est:wp62h02.x1 /CLONE=IMAGE:2466387 /UG=Hs.120911 neurexophilin 4 AI933199 neurexophilin 4 NXPH4 11247 NM_007224 0007218 // neuropeptide signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 221968_s_at AW014373 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW014373 /FEA=EST /DB_XREF=gi:5863130 /DB_XREF=est:UI-H-BI0-aac-a-03-0-UI.s1 /CLONE=IMAGE:2708644 /UG=Hs.116056 mesenchymal stem cell protein DSC43 AW014373 zinc finger protein 771 ZNF771 51333 NM_001142305 /// NM_016643 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221969_at BF510692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF510692 /FEA=EST /DB_XREF=gi:11593990 /DB_XREF=est:UI-H-BI4-aof-f-12-0-UI.s1 /CLONE=IMAGE:3084815 /UG=Hs.22030 paired box gene 5 (B-cell lineage specific activator protein) BF510692 paired box 5 PAX5 5079 NM_001280547 /// NM_001280548 /// NM_001280549 /// NM_001280550 /// NM_001280551 /// NM_001280552 /// NM_001280553 /// NM_001280554 /// NM_001280555 /// NM_001280556 /// NM_016734 /// NR_103999 /// NR_104000 /// XM_005251481 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 221970_s_at AU158148 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU158148 /FEA=EST /DB_XREF=gi:11019669 /DB_XREF=est:AU158148 /CLONE=PLACE1011221 /UG=Hs.321105 Homo sapiens cDNA: FLJ21737 fis, clone COLF3396 AU158148 nucleolar protein 11 NOL11 25926 NM_015462 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0030490 // maturation of SSU-rRNA // inferred from mutant phenotype /// 1901838 // positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0034455 // t-UTP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221971_x_at BE672818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE672818 /FEA=EST /DB_XREF=gi:10033359 /DB_XREF=est:7d24c01.x1 /CLONE=IMAGE:3248160 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 BE672818 ArfGAP with GTPase domain, ankyrin repeat and PH domain 10 /// ankyrin repeat and GTPase domain Arf GTPase activating protein 11 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 /// ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 /// BMS1 pseudogene 5 /// centaurin, gamma-like family, member 12 pseudogene /// arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4-like AGAP10 /// AGAP11 /// AGAP4 /// AGAP5 /// AGAP9 /// BMS1P5 /// CTGLF12P /// LOC101060581 119016 /// 119385 /// 399761 /// 414224 /// 642517 /// 728127 /// 729092 /// 101060581 NM_001040053 /// NM_001077686 /// NM_001144000 /// NM_001190810 /// NM_001276343 /// NM_001276344 /// NM_001291379 /// NM_133446 /// NM_133447 /// NR_003611 /// NR_026566 /// NR_029396 /// XM_005271797 /// XM_005271800 /// XM_005276381 /// XM_005276382 /// XM_006709937 /// XM_006717619 /// XM_006717620 /// XM_006717621 /// XM_006717622 /// XM_006718092 /// XM_006726520 /// XR_432570 /// XR_432571 /// XR_432580 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 221972_s_at AL571362 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL571362 /FEA=EST /DB_XREF=gi:12928582 /DB_XREF=est:AL571362 /CLONE=CS0DI009YD14 (3 prime) /UG=Hs.42806 calcium binding protein Cab45 precursor, AL571362 stromal cell derived factor 4 SDF4 51150 NM_016176 /// NM_016547 0006887 // exocytosis // inferred from electronic annotation /// 0009650 // UV protection // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0070625 // zymogen granule exocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0032059 // bleb // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221973_at AI983904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983904 /FEA=EST /DB_XREF=gi:5811123 /DB_XREF=est:wz55d05.x1 /CLONE=IMAGE:2561961 /UG=Hs.79732 fibulin 1 AI983904 uncharacterized LOC100506076 /// uncharacterized LOC100506123 LOC100506076 /// LOC100506123 100506076 /// 100506123 NR_040097 /// NR_103732 /// NR_103733 221974_at AW770748 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW770748 /FEA=EST /DB_XREF=gi:7702795 /DB_XREF=est:hl90a07.x1 /CLONE=IMAGE:3009204 /UG=Hs.5022 imprinted in Prader-Willi syndrome AW770748 imprinted in Prader-Willi syndrome (non-protein coding) /// uncharacterized LOC101930404 /// Prader Willi/Angelman region RNA, SNRPN neighbor /// small nucleolar RNA, C/D box 107 /// small nucleolar RNA, C/D box 115-13 /// small nucleolar RNA, C/D box 115-26 /// small nucleolar RNA, C/D box 115-7 /// small nucleolar RNA, C/D box 116-22 /// small nucleolar RNA, C/D box 116-28 /// small nucleolar RNA, C/D box 116-4 /// small nuclear ribonucleoprotein polypeptide N IPW /// LOC101930404 /// PWARSN /// SNORD107 /// SNORD115-13 /// SNORD115-26 /// SNORD115-7 /// SNORD116-22 /// SNORD116-28 /// SNORD116-4 /// SNRPN 3653 /// 6638 /// 91380 /// 347746 /// 100033416 /// 100033433 /// 100033444 /// 100033450 /// 100033802 /// 100033820 /// 101930404 NM_003097 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 /// NR_001293 /// NR_003299 /// NR_003305 /// NR_003319 /// NR_003336 /// NR_003343 /// NR_003361 /// NR_022011 /// NR_023915 /// XR_250593 /// XR_426491 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 221975_s_at AI539305 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI539305 /FEA=EST /DB_XREF=gi:4453440 /DB_XREF=est:te50h12.x1 /CLONE=IMAGE:2090183 /UG=Hs.153452 chromosome 21 open reading frame 2 AI539305 /// chromosome 21 open reading frame 2 AP001062.7 /// C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 221976_s_at AW207448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW207448 /FEA=EST /DB_XREF=gi:6506944 /DB_XREF=est:UI-H-BI1-afi-f-11-0-UI.s1 /CLONE=IMAGE:2721956 /UG=Hs.127842 CGI-142 AW207448 hepatoma-derived growth factor, related protein 3 HDGFRP3 50810 NM_016073 /// XM_006720554 0008283 // cell proliferation // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation 221977_at AW303460 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW303460 /FEA=EST /DB_XREF=gi:6713149 /DB_XREF=est:xv19c11.x1 /CLONE=IMAGE:2813588 /UG=Hs.168357 T-box 2 AW303460 T-box 2 TBX2 6909 NM_005994 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048596 // embryonic camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060465 // pharynx development // inferred from sequence or structural similarity /// 0060560 // developmental growth involved in morphogenesis // inferred from electronic annotation /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 1901208 // negative regulation of heart looping // inferred from sequence or structural similarity /// 1901211 // negative regulation of cardiac chamber formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 221978_at BE138825 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE138825 /FEA=EST /DB_XREF=gi:8601325 /DB_XREF=est:xw96a07.x1 /CLONE=IMAGE:2835828 /UG=Hs.110309 major histocompatibility complex, class I, F BE138825 major histocompatibility complex, class I, F HLA-F 3134 NM_001098478 /// NM_001098479 /// NM_018950 /// XM_005249054 /// XM_005272809 /// XM_005274960 /// XM_005275115 /// XM_005275390 /// XM_005275547 /// XM_005275548 /// XM_006726089 /// XM_006726090 /// XM_006726091 /// XM_006726092 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0042605 // peptide antigen binding // not recorded /// 0046978 // TAP1 binding // inferred from physical interaction /// 0046979 // TAP2 binding // inferred from physical interaction 221979_at AI150117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI150117 /FEA=EST /DB_XREF=gi:3678586 /DB_XREF=est:qf44e06.x1 /CLONE=IMAGE:1752898 /UG=Hs.121573 ESTs AI150117 TOPORS antisense RNA 1 TOPORS-AS1 100129250 NR_033991 /// NR_033992 /// NR_102376 /// NR_102377 221980_at AL117592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117592.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586H1921 (from clone DKFZp586H1921). /FEA=mRNA /DB_XREF=gi:5912156 /UG=Hs.179765 Homo sapiens mRNA; cDNA DKFZp586H1921 (from clone DKFZp586H1921) AL117592 elastin microfibril interfacer 2 EMILIN2 84034 NM_032048 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // non-traceable author statement 221981_s_at AA702154 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA702154 /FEA=EST /DB_XREF=gi:2705267 /DB_XREF=est:zi91e08.s1 /CLONE=IMAGE:448166 /UG=Hs.180058 hypothetical protein MGC11230 AA702154 WD repeat domain 59 WDR59 79726 NM_030581 /// XM_005256146 /// XM_005256147 0005515 // protein binding // inferred from electronic annotation 221982_x_at AA034498 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA034498 /FEA=EST /DB_XREF=gi:1506344 /DB_XREF=est:zk23c03.s1 /CLONE=IMAGE:471364 /UG=Hs.18212 DNA segment on chromosome X (unique) 9879 expressed sequence AA034498 221983_at AL040896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL040896 /FEA=EST /DB_XREF=gi:5409841 /DB_XREF=est:DKFZp434I2415_s1 /CLONE=DKFZp434I2415 /UG=Hs.22412 hypothetical protein MGC3035 AL040896 family with sequence similarity 134, member A FAM134A 79137 NM_024293 /// XM_005246848 /// XM_005246849 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221984_s_at AL040896 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL040896 /FEA=EST /DB_XREF=gi:5409841 /DB_XREF=est:DKFZp434I2415_s1 /CLONE=DKFZp434I2415 /UG=Hs.22412 hypothetical protein MGC3035 AL040896 family with sequence similarity 134, member A FAM134A 79137 NM_024293 /// XM_005246848 /// XM_005246849 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221985_at AW006750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006750 /FEA=EST /DB_XREF=gi:5855528 /DB_XREF=est:wr28h09.x1 /CLONE=IMAGE:2489057 /UG=Hs.246875 hypothetical protein FLJ20059 AW006750 kelch-like family member 24 KLHL24 54800 NM_017644 /// XM_005247552 /// XM_005247553 /// XM_005247554 /// XM_005247555 /// XM_005247556 /// XM_006713674 /// XR_241499 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221986_s_at AW006750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW006750 /FEA=EST /DB_XREF=gi:5855528 /DB_XREF=est:wr28h09.x1 /CLONE=IMAGE:2489057 /UG=Hs.246875 hypothetical protein FLJ20059 AW006750 kelch-like family member 24 KLHL24 54800 NM_017644 /// XM_005247552 /// XM_005247553 /// XM_005247554 /// XM_005247555 /// XM_005247556 /// XM_006713674 /// XR_241499 0005737 // cytoplasm // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 221987_s_at AI803633 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI803633 /FEA=EST /DB_XREF=gi:5369105 /DB_XREF=est:tc43c08.x1 /CLONE=IMAGE:2067374 /UG=Hs.27335 serine racemase AI803633 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) TSR1 55720 NM_018128 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity 0044822 // poly(A) RNA binding // inferred from direct assay 221988_at AA463853 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA463853 /FEA=EST /DB_XREF=gi:2188737 /DB_XREF=est:zx97b05.s1 /CLONE=IMAGE:811665 /UG=Hs.268049 hypothetical protein AA463853 small integral membrane protein 7 SMIM7 79086 NM_024104 /// XM_005260074 /// XR_244083 /// XR_244084 /// XR_244085 /// XR_244086 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 221989_at AW057781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW057781 /FEA=EST /DB_XREF=gi:5933420 /DB_XREF=est:wx03f09.x1 /CLONE=IMAGE:2542601 /UG=Hs.29797 ribosomal protein L10 AW057781 ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70 RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 221990_at AI948472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI948472 /FEA=EST /DB_XREF=gi:5740782 /DB_XREF=est:wq06c01.x1 /CLONE=IMAGE:2470464 /UG=Hs.73149 paired box gene 8 AI948472 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 221991_at AI937333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI937333 /FEA=EST /DB_XREF=gi:5676203 /DB_XREF=est:wp75h10.x1 /CLONE=IMAGE:2467651 /UG=Hs.55069 neurexophilin 3 AI937333 neurexophilin 3 NXPH3 11248 NM_007225 0007218 // neuropeptide signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation 221992_at AI925734 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI925734 /FEA=EST /DB_XREF=gi:5661698 /DB_XREF=est:wo34g08.x1 /CLONE=IMAGE:2457278 /UG=Hs.110613 KIAA0220 protein AI925734 nuclear pore complex interacting protein family, member B15 NPIPB15 440348 NM_001018059 /// XM_005256273 /// XM_006721357 /// XM_006726636 0019752 // carboxylic acid metabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 221993_s_at BE328802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE328802 /FEA=EST /DB_XREF=gi:9202578 /DB_XREF=est:hv97b09.x1 /CLONE=IMAGE:3181337 /UG=Hs.134846 Human DNA sequence from clone 316G12 on chromosome 16. Contains the gene for C2 domain protein KIAA0734, the gene for a novel protein similar to predicted yeast, worm and archae-bacterial proteins, a novel gene and the 3 part of the gene for a novel prot BE328802 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) TSR3 115939 NM_001001410 0006364 // rRNA processing // inferred from electronic annotation 221994_at AA196325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA196325 /FEA=EST /DB_XREF=gi:1791959 /DB_XREF=est:zp99f09.s1 /CLONE=IMAGE:628361 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) AA196325 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 221995_s_at BF195165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF195165 /FEA=EST /DB_XREF=gi:11081754 /DB_XREF=est:7n16b01.x1 /CLONE=IMAGE:3564624 /UG=Hs.182695 hypothetical protein MGC3243 BF195165 221996_s_at AW170546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW170546 /FEA=EST /DB_XREF=gi:6402071 /DB_XREF=est:xn63c11.x1 /CLONE=IMAGE:2698388 /UG=Hs.73919 clathrin, light polypeptide (Lcb) AW170546 clathrin, light chain B CLTB 1212 NM_001834 /// NM_007097 /// NR_045724 /// XM_006714818 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 221997_s_at AI560951 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI560951 /FEA=EST /DB_XREF=gi:4511292 /DB_XREF=est:tn18f12.x1 /CLONE=IMAGE:2168015 /UG=Hs.79572 cathepsin D (lysosomal aspartyl protease) AI560951 mitochondrial ribosomal protein L52 MRPL52 122704 NM_178336 /// NM_180982 /// NM_181304 /// NM_181305 /// NM_181306 /// NM_181307 /// XM_005267325 /// XM_005267326 /// XM_005267327 /// XM_005267328 /// XM_006720027 0006412 // translation // inferred from sequence or structural similarity 0005762 // mitochondrial large ribosomal subunit // inferred from sequence or structural similarity 0003735 // structural constituent of ribosome // inferred from sequence or structural similarity 221998_s_at BF062886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062886 /FEA=EST /DB_XREF=gi:10821796 /DB_XREF=est:7h71f04.x1 /CLONE=IMAGE:3321439 /UG=Hs.98289 VRK3 for vaccinia related kinase 3 BF062886 vaccinia related kinase 3 VRK3 51231 NM_001025778 /// NM_016440 /// XM_005258971 /// XM_005258972 /// XM_005258974 /// XM_006723237 /// XM_006723238 /// XR_243939 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation 221999_at BF062886 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF062886 /FEA=EST /DB_XREF=gi:10821796 /DB_XREF=est:7h71f04.x1 /CLONE=IMAGE:3321439 /UG=Hs.98289 VRK3 for vaccinia related kinase 3 BF062886 vaccinia related kinase 3 VRK3 51231 NM_001025778 /// NM_016440 /// XM_005258971 /// XM_005258972 /// XM_005258974 /// XM_006723237 /// XM_006723238 /// XR_243939 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation 222000_at AI915947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI915947 /FEA=EST /DB_XREF=gi:5635802 /DB_XREF=est:wg96e01.x1 /CLONE=IMAGE:2379096 /UG=Hs.28212 ESTs AI915947 chromosome 1 open reading frame 174 C1orf174 339448 NM_207356 /// XM_005244743 0005634 // nucleus // inferred from direct assay 222001_x_at AI160126 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI160126 /FEA=EST /DB_XREF=gi:3693506 /DB_XREF=est:qb51h08.x1 /CLONE=IMAGE:1703679 /UG=Hs.295901 KIAA0493 protein AI160126 long intergenic non-protein coding RNA 623 /// long intergenic non-protein coding RNA 869 LINC00623 /// LINC00869 57234 /// 728855 NR_024510 /// NR_024511 /// NR_024584 /// NR_046135 /// NR_046136 /// NR_046137 /// NR_046138 /// NR_046139 /// NR_109754 /// NR_111950 /// NR_111951 /// NR_111952 /// NR_111953 /// XR_254365 /// XR_426752 /// XR_426842 /// XR_426843 /// XR_431230 /// XR_431279 /// XR_431280 /// XR_431281 222002_at BE503090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE503090 /FEA=EST /DB_XREF=gi:9705498 /DB_XREF=est:hz83d05.x1 /CLONE=IMAGE:3214569 /UG=Hs.81057 hypothetical protein MGC2718 BE503090 chromosome 7 open reading frame 26 C7orf26 79034 NM_024067 /// XM_005249845 /// XR_242101 222003_s_at BE857715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE857715 /FEA=EST /DB_XREF=gi:10372018 /DB_XREF=est:7g46g03.x1 /CLONE=IMAGE:3309556 /UG=Hs.8982 ESTs, Highly similar to KIAA1395 protein H.sapiens BE857715 dedicator of cytokinesis 6 DOCK6 57572 NM_020812 /// XM_005260000 /// XM_005260001 /// XM_006722802 /// XM_006722803 /// XM_006722804 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 222004_s_at AA534504 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA534504 /FEA=EST /DB_XREF=gi:2278757 /DB_XREF=est:nf80e08.s1 /CLONE=IMAGE:926246 /UG=Hs.8982 ESTs, Highly similar to KIAA1395 protein H.sapiens AA534504 dedicator of cytokinesis 6 DOCK6 57572 NM_020812 /// XM_005260000 /// XM_005260001 /// XM_006722802 /// XM_006722803 /// XM_006722804 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 222005_s_at AL538966 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL538966 /FEA=EST /DB_XREF=gi:12867755 /DB_XREF=est:AL538966 /CLONE=CS0DF030YJ17 (5 prime) /UG=Hs.179915 guanine nucleotide binding protein (G protein), gamma 3 AL538966 guanine nucleotide binding protein (G protein), gamma 3 GNG3 2785 NM_012202 /// XM_006718500 /// XM_006718501 0000187 // activation of MAPK activity // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 222006_at AI359368 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI359368 /FEA=EST /DB_XREF=gi:4110989 /DB_XREF=est:qy27h02.x1 /CLONE=IMAGE:2013267 /UG=Hs.120165 leucine zipper-EF-hand containing transmembrane protein 1 AI359368 leucine zipper-EF-hand containing transmembrane protein 1 LETM1 3954 NM_012318 /// XM_005247970 /// XM_006713884 0042407 // cristae formation // inferred from mutant phenotype 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222007_s_at N95418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N95418 /FEA=EST /DB_XREF=gi:1267902 /DB_XREF=est:zb66e11.s1 /CLONE=IMAGE:308588 /UG=Hs.173464 FK506-binding protein 8 (38kD) N95418 FK506 binding protein 8, 38kDa FKBP8 23770 NM_012181 /// XM_005259841 /// XM_005259842 /// XM_005259844 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0061077 // chaperone-mediated protein folding // not recorded 0005789 // endoplasmic reticulum membrane // not recorded /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222008_at NM_001851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_001851.1 /DEF=Homo sapiens collagen, type IX, alpha 1 (COL9A1), mRNA. /FEA=CDS /GEN=COL9A1 /PROD=collagen, type IX, alpha 1 /DB_XREF=gi:4502964 /UG=Hs.154850 collagen, type IX, alpha 1 /FL=gb:NM_001851.1 NM_001851 collagen, type IX, alpha 1 COL9A1 1297 NM_001851 /// NM_078485 /// XM_006715331 0001894 // tissue homeostasis // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005594 // collagen type IX trimer // inferred from direct assay /// 0005594 // collagen type IX trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0030020 // extracellular matrix structural constituent conferring tensile strength // inferred by curator /// 0046872 // metal ion binding // inferred from electronic annotation 222009_at AI829081 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI829081 /FEA=EST /DB_XREF=gi:5449752 /DB_XREF=est:wj38d08.x1 /CLONE=IMAGE:2405103 /UG=Hs.274361 amiloride-sensitive cation channel 2, neuronal AI829081 cementum protein 1 CEMP1 752014 NM_001048212 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // inferred from electronic annotation /// 0019262 // N-acetylneuraminate catabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0008448 // N-acetylglucosamine-6-phosphate deacetylase activity // inferred from direct assay /// 0008448 // N-acetylglucosamine-6-phosphate deacetylase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222010_at BF224073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224073 /FEA=EST /DB_XREF=gi:11131299 /DB_XREF=est:7q83e05.x1 /CLONE=IMAGE:3704936 /UG=Hs.278544 acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) BF224073 small nucleolar RNA, H/ACA box 29 /// t-complex 1 SNORA29 /// TCP1 6950 /// 677812 NM_001008897 /// NM_030752 /// NR_002965 0006457 // protein folding // traceable author statement /// 0007021 // tubulin complex assembly // non-traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 222011_s_at BF224073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF224073 /FEA=EST /DB_XREF=gi:11131299 /DB_XREF=est:7q83e05.x1 /CLONE=IMAGE:3704936 /UG=Hs.278544 acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) BF224073 small nucleolar RNA, H/ACA box 29 /// t-complex 1 SNORA29 /// TCP1 6950 /// 677812 NM_001008897 /// NM_030752 /// NR_002965 0006457 // protein folding // traceable author statement /// 0007021 // tubulin complex assembly // non-traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0000242 // pericentriolar material // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 222012_at AA535066 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA535066 /FEA=EST /DB_XREF=gi:2279319 /DB_XREF=est:nf84a10.s1 /CLONE=IMAGE:926586 /UG=Hs.298553 Homo sapiens, clone IMAGE:3953631, mRNA, partial cds AA535066 DDB1 and CUL4 associated factor 15 DCAF15 90379 NM_138353 0016567 // protein ubiquitination // inferred from electronic annotation 222013_x_at BE348837 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE348837 /FEA=EST /DB_XREF=gi:9260690 /DB_XREF=est:ht74f05.x1 /CLONE=IMAGE:3152481 /UG=Hs.325173 hypothetical protein FLJ10661 BE348837 family with sequence similarity 86, member A FAM86A 196483 NM_001289029 /// NM_201400 /// NM_201598 /// XM_005255157 /// XM_005255158 /// XM_006720859 0005737 // cytoplasm // inferred from electronic annotation 222014_x_at AI249752 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI249752 /FEA=EST /DB_XREF=gi:3846281 /DB_XREF=est:qj64g10.x1 /CLONE=IMAGE:1864290 /UG=Hs.326655 Homo sapiens CGI-02 protein (CGI-02), mRNA AI249752 mitochondrial tRNA translation optimization 1 MTO1 25821 NM_001123226 /// NM_012123 /// NM_133645 /// XM_006715444 /// XM_006715445 /// XM_006715446 /// XM_006715447 /// XM_006715448 /// XM_006715449 0002098 // tRNA wobble uridine modification // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070899 // mitochondrial tRNA wobble uridine modification // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 222015_at AW192876 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW192876 /FEA=EST /DB_XREF=gi:6471575 /DB_XREF=est:xl54h02.x1 /CLONE=IMAGE:2678547 /UG=Hs.79658 casein kinase 1, epsilon AW192876 casein kinase 1, epsilon CSNK1E 1454 NM_001894 /// NM_152221 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222016_s_at AW086021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW086021 /FEA=EST /DB_XREF=gi:6041091 /DB_XREF=est:xc75a03.x1 /CLONE=IMAGE:2590060 /UG=Hs.104842 hypothetical protein FLJ23407 AW086021 zinc finger and SCAN domain containing 31 ZSCAN31 64288 NM_001135215 /// NM_001135216 /// NM_001243241 /// NM_001243242 /// NM_001243243 /// NM_001243244 /// NM_030899 /// NM_145909 /// XM_005249295 /// XM_005249296 /// XR_241913 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222017_x_at AI660075 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI660075 /FEA=EST /DB_XREF=gi:4763645 /DB_XREF=est:we56c08.x1 /CLONE=IMAGE:2345102 /UG=Hs.125742 leucine-rich neuronal protein AI660075 leucine-rich repeats and calponin homology (CH) domain containing 4 LRCH4 4034 NM_001289934 /// NM_002319 /// XM_005250346 /// XM_005250347 0007399 // nervous system development // traceable author statement 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222018_at AI992187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI992187 /FEA=EST /DB_XREF=gi:5839092 /DB_XREF=est:wt75f11.x1 /CLONE=IMAGE:2513325 /UG=Hs.158164 ATP-binding cassette, sub-family B (MDRTAP), member 2 AI992187 nascent polypeptide-associated complex alpha subunit NACA 4666 NM_001113201 /// NM_001113202 /// NM_001113203 /// NM_005594 /// NR_045277 /// XM_006719412 /// XM_006719413 /// XM_006719414 /// XM_006719415 /// XM_006719416 /// XM_006719417 /// XM_006719418 /// XM_006719419 /// XM_006719420 /// XM_006719421 0003231 // cardiac ventricle development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 1901227 // negative regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 1901228 // positive regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005854 // nascent polypeptide-associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from sequence or structural similarity 222019_at AW007185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW007185 /FEA=EST /DB_XREF=gi:5855963 /DB_XREF=est:ws50c01.x1 /CLONE=IMAGE:2500608 /UG=Hs.205736 HLA class II region expressed gene KE2 AW007185 microRNA 6834 /// prefoldin subunit 6 MIR6834 /// PFDN6 10471 /// 102465501 NM_001185181 /// NM_001265595 /// NM_001265596 /// NM_014260 /// NR_106892 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0016272 // prefoldin complex // inferred from direct assay 0051082 // unfolded protein binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from direct assay 222020_s_at AW117456 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW117456 /FEA=EST /DB_XREF=gi:6086040 /DB_XREF=est:xd92a06.x1 /CLONE=IMAGE:2605042 /UG=Hs.288433 neurotrimin AW117456 neurotrimin-like /// neurotrimin LOC102725271 /// NTM 50863 /// 102725271 NM_001048209 /// NM_001144058 /// NM_001144059 /// NM_016522 /// XM_005271580 /// XM_005271581 /// XM_005271582 /// XM_006709956 /// XM_006718854 /// XM_006718855 /// XM_006718856 /// XM_006718857 0007155 // cell adhesion // inferred from electronic annotation /// 0008038 // neuron recognition // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 222021_x_at AI348006 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI348006 /FEA=EST /DB_XREF=gi:4085212 /DB_XREF=est:qp61b05.x1 /CLONE=IMAGE:1927473 /UG=Hs.469 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) AI348006 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 /// succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2 SDHAP1 /// SDHAP2 255812 /// 727956 NR_003264 /// NR_003265 0055114 // oxidation-reduction process // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation 222022_at AW574818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW574818 /FEA=EST /DB_XREF=gi:7246357 /DB_XREF=est:UI-HF-BK0-abi-e-06-0-UI.s1 /CLONE=IMAGE:3056362 /UG=Hs.32374 ESTs, Weakly similar to KIAA1528 protein H.sapiens AW574818 deltex 3, E3 ubiquitin ligase DTX3 196403 NM_001286245 /// NM_001286246 /// NM_178502 /// XM_005268697 /// XM_005268698 /// XM_005268700 /// XM_005268703 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 222023_at AK022014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022014.1 /DEF=Homo sapiens cDNA FLJ11952 fis, clone HEMBB1000831, weakly similar to Homo sapiens breast cancer nuclear receptor-binding auxiliary protein (BRX) mRNA. /FEA=mRNA /DB_XREF=gi:10433327 /UG=Hs.306619 Homo sapiens cDNA FLJ11952 fis, clone HEMBB1000831, weakly similar to Homo sapiens breast cancer nuclear receptor-binding auxiliary protein (BRX) mRNA AK022014 A kinase (PRKA) anchor protein 13 AKAP13 11214 NM_001270546 /// NM_006738 /// NM_007200 /// NM_144767 /// XM_005254839 /// XM_005254840 /// XM_005254841 /// XM_005254842 /// XM_005254843 /// XM_005254844 /// XM_005254845 /// XM_005254846 /// XM_005254847 /// XM_005254848 /// XM_005254849 /// XM_005254850 /// XM_005254851 /// XM_005254852 /// XM_005254853 /// XM_005254854 /// XM_005254855 /// XM_005254856 /// XM_006720376 /// XM_006720377 /// XM_006720378 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 222024_s_at AK022014 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022014.1 /DEF=Homo sapiens cDNA FLJ11952 fis, clone HEMBB1000831, weakly similar to Homo sapiens breast cancer nuclear receptor-binding auxiliary protein (BRX) mRNA. /FEA=mRNA /DB_XREF=gi:10433327 /UG=Hs.306619 Homo sapiens cDNA FLJ11952 fis, clone HEMBB1000831, weakly similar to Homo sapiens breast cancer nuclear receptor-binding auxiliary protein (BRX) mRNA AK022014 A kinase (PRKA) anchor protein 13 AKAP13 11214 NM_001270546 /// NM_006738 /// NM_007200 /// NM_144767 /// XM_005254839 /// XM_005254840 /// XM_005254841 /// XM_005254842 /// XM_005254843 /// XM_005254844 /// XM_005254845 /// XM_005254846 /// XM_005254847 /// XM_005254848 /// XM_005254849 /// XM_005254850 /// XM_005254851 /// XM_005254852 /// XM_005254853 /// XM_005254854 /// XM_005254855 /// XM_005254856 /// XM_006720376 /// XM_006720377 /// XM_006720378 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010611 // regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051168 // nuclear export // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1900169 // regulation of glucocorticoid mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from electronic annotation 222025_s_at AI991887 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991887 /FEA=EST /DB_XREF=gi:5838792 /DB_XREF=est:wu32h11.x1 /CLONE=IMAGE:2521797 /UG=Hs.305882 5-oxoprolinase (ATP-hydrolysing) AI991887 5-oxoprolinase (ATP-hydrolysing) OPLAH 26873 NM_017570 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017168 // 5-oxoprolinase (ATP-hydrolyzing) activity // traceable author statement 222026_at BF437591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF437591 /FEA=EST /DB_XREF=gi:11449997 /DB_XREF=est:7p74e11.x1 /CLONE=IMAGE:3651572 /UG=Hs.301404 RNA binding motif protein 3 BF437591 RNA binding motif (RNP1, RRM) protein 3 RBM3 5935 NM_001017430 /// NM_001017431 /// NM_006743 0006396 // RNA processing // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0035196 // production of miRNAs involved in gene silencing by miRNA // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0015934 // large ribosomal subunit // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043023 // ribosomal large subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222027_at AW515443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW515443 /FEA=EST /DB_XREF=gi:7153525 /DB_XREF=est:xu70e08.x1 /CLONE=IMAGE:2807078 /UG=Hs.118064 similar to rat nuclear ubiquitous casein kinase 2 AW515443 nuclear casein kinase and cyclin-dependent kinase substrate 1 NUCKS1 64710 NM_022731 /// XM_005245453 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 222028_at AI967981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI967981 /FEA=EST /DB_XREF=gi:5764799 /DB_XREF=est:wu11f05.x1 /CLONE=IMAGE:2516673 /UG=Hs.115065 ESTs AI967981 zinc finger protein 45 ZNF45 7596 NM_003425 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 222029_x_at NM_014260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_014260.1 /DEF=Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA. /FEA=CDS /GEN=HKE2 /PROD=HLA class II region expressed gene KE2 /DB_XREF=gi:7657161 /UG=Hs.205736 HLA class II region expressed gene KE2 /FL=gb:NM_014260.1 NM_014260 microRNA 6834 /// prefoldin subunit 6 MIR6834 /// PFDN6 10471 /// 102465501 NM_001185181 /// NM_001265595 /// NM_001265596 /// NM_014260 /// NR_106892 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay 0016272 // prefoldin complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from direct assay 222030_at AW024335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024335 /FEA=EST /DB_XREF=gi:5877865 /DB_XREF=est:wt69h11.x1 /CLONE=IMAGE:2512773 /UG=Hs.112058 CD27-binding (Siva) protein AW024335 SIVA1, apoptosis-inducing factor SIVA1 10572 NM_006427 /// NM_021709 0006915 // apoptotic process // inferred from electronic annotation /// 0006924 // activation-induced cell death of T cells // inferred from direct assay /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001618 // virus receptor activity // inferred from sequence or structural similarity /// 0005175 // CD27 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222031_at AW452796 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW452796 /FEA=EST /DB_XREF=gi:6993572 /DB_XREF=est:UI-H-BI3-alx-f-06-0-UI.s1 /CLONE=IMAGE:3069059 /UG=Hs.120769 Homo sapiens cDNA FLJ20463 fis, clone KAT06143 AW452796 zinc finger protein 839 pseudogene LOC389906 389906 NR_034031 222032_s_at BF591638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF591638 /FEA=EST /DB_XREF=gi:11683962 /DB_XREF=est:7n53g03.x1 /CLONE=IMAGE:3568325 /UG=Hs.129663 ESTs BF591638 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_001286457 /// NM_001286458 /// NM_003470 0006281 // DNA repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0002039 // p53 binding // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 222033_s_at AA058828 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA058828 /FEA=EST /DB_XREF=gi:1551654 /DB_XREF=est:zf66f10.s1 /CLONE=IMAGE:381931 /UG=Hs.138671 fms-related tyrosine kinase 1 (vascular endothelial growth factorvascular permeability factor receptor) AA058828 fms-related tyrosine kinase 1 FLT1 2321 NM_001159920 /// NM_001160030 /// NM_001160031 /// NM_002019 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0036323 // vascular endothelial growth factor receptor-1 signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048598 // embryonic morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0036326 // VEGF-A-activated receptor activity // inferred from direct assay /// 0036327 // VEGF-B-activated receptor activity // inferred from direct assay /// 0036332 // placental growth factor-activated receptor activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation 222034_at AA443762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA443762 /FEA=EST /DB_XREF=gi:2156437 /DB_XREF=est:zw95e04.s1 /CLONE=IMAGE:784734 /UG=Hs.5662 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 AA443762 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /// small nucleolar RNA, C/D box 95 /// small nucleolar RNA, C/D box 96A GNB2L1 /// SNORD95 /// SNORD96A 10399 /// 619570 /// 619571 NM_006098 /// NR_002591 /// NR_002592 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030822 // positive regulation of cAMP catabolic process // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from mutant phenotype /// 0051302 // regulation of cell division // inferred from sequence or structural similarity /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051901 // positive regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from electronic annotation /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from genetic interaction /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0001891 // phagocytic cup // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from direct assay /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008200 // ion channel inhibitor activity // inferred from sequence or structural similarity /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay /// 0032947 // protein complex scaffold // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 222035_s_at AI984479 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI984479 /FEA=EST /DB_XREF=gi:5811756 /DB_XREF=est:wr83e06.x1 /CLONE=IMAGE:2494306 /UG=Hs.49007 poly(A) polymerase alpha AI984479 poly(A) polymerase alpha PAPOLA 10914 NM_001252006 /// NM_001252007 /// NM_001293627 /// NM_001293628 /// NM_001293632 /// NM_032632 /// XM_005267280 /// XM_005267281 /// XM_005267282 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043631 // RNA polyadenylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 222036_s_at AI859865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI859865 /FEA=EST /DB_XREF=gi:5513481 /DB_XREF=est:wm21f03.x1 /CLONE=IMAGE:2436605 /UG=Hs.154443 minichromosome maintenance deficient (S. cerevisiae) 4 AI859865 minichromosome maintenance complex component 4 MCM4 4173 NM_005914 /// NM_182746 /// XM_005251234 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 222037_at AI859865 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI859865 /FEA=EST /DB_XREF=gi:5513481 /DB_XREF=est:wm21f03.x1 /CLONE=IMAGE:2436605 /UG=Hs.154443 minichromosome maintenance deficient (S. cerevisiae) 4 AI859865 minichromosome maintenance complex component 4 MCM4 4173 NM_005914 /// NM_182746 /// XM_005251234 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 222038_s_at AA993099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA993099 /FEA=EST /DB_XREF=gi:3179644 /DB_XREF=est:ou01h08.s1 /CLONE=IMAGE:1625055 /UG=Hs.6153 CGI-48 protein AA993099 UTP18 small subunit (SSU) processome component homolog (yeast) UTP18 51096 NM_016001 /// XM_006721930 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 222039_at AA292789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA292789 /FEA=EST /DB_XREF=gi:1941611 /DB_XREF=est:zt56d09.s1 /CLONE=IMAGE:726353 /UG=Hs.274448 hypothetical protein FLJ11029 AA292789 kinesin family member 18B KIF18B 146909 NM_001080443 /// NM_001264573 /// NM_001265577 /// XM_005257077 0000278 // mitotic cell cycle // inferred from direct assay /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0007019 // microtubule depolymerization // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051302 // regulation of cell division // inferred from direct assay 0000235 // astral microtubule // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from direct assay /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction 222040_at AI144007 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI144007 /FEA=EST /DB_XREF=gi:3665816 /DB_XREF=est:qb33c06.x1 /CLONE=IMAGE:1698058 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 AI144007 heterogeneous nuclear ribonucleoprotein A1 HNRNPA1 3178 NM_002136 /// NM_031157 /// XM_005268826 /// XR_245923 /// XR_245924 0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 222041_at BG235929 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG235929 /FEA=EST /DB_XREF=gi:12749776 /DB_XREF=est:naf18h02.x1 /CLONE=IMAGE:4141658 /UG=Hs.26034 ESTs BG235929 diphthamide biosynthesis 1 /// ovarian tumor suppressor candidate 2 DPH1 /// OVCA2 1801 /// 124641 NM_001383 /// NM_080822 0006412 // translation // traceable author statement /// 0008152 // metabolic process // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // non-traceable author statement 222042_x_at BF056534 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056534 /FEA=EST /DB_XREF=gi:10810430 /DB_XREF=est:7k06e09.x1 /CLONE=IMAGE:3443441 /UG=Hs.123469 ESTs, Weakly similar to AF208855 1 BM-013 H.sapiens BF056534 mex-3 RNA binding family member D MEX3D 399664 NM_001174118 /// NM_203304 /// XM_006726771 0010609 // mRNA localization resulting in posttranscriptional regulation of gene expression // non-traceable author statement /// 0061157 // mRNA destabilization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0008270 // zinc ion binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 222043_at AI982754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI982754 /FEA=EST /DB_XREF=gi:5809973 /DB_XREF=est:wz28g10.x1 /CLONE=IMAGE:2559426 /UG=Hs.75106 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) AI982754 clusterin CLU 1191 NM_001831 /// NR_038335 /// NR_045494 /// XM_006716284 0000902 // cell morphogenesis // inferred from direct assay /// 0001774 // microglial cell activation // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred by curator /// 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0017038 // protein import // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032286 // central nervous system myelin maintenance // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032463 // negative regulation of protein homooligomerization // inferred from mutant phenotype /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051131 // chaperone-mediated protein complex assembly // inferred from direct assay /// 0051788 // response to misfolded protein // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061518 // microglial cell proliferation // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from sequence or structural similarity /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902847 // regulation of neuronal signal transduction // inferred from mutant phenotype /// 1902949 // positive regulation of tau-protein kinase activity // inferred from mutant phenotype /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from mutant phenotype /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034366 // spherical high-density lipoprotein particle // inferred from direct assay /// 0042583 // chromaffin granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097418 // neurofibrillary tangle // inferred from direct assay /// 0097440 // apical dendrite // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from direct assay /// 0051787 // misfolded protein binding // inferred from physical interaction 222044_at AI199589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI199589 /FEA=EST /DB_XREF=gi:3752195 /DB_XREF=est:qi57d04.x1 /CLONE=IMAGE:1860583 /UG=Hs.272814 hypothetical protein DKFZp434E1723 AI199589 222045_s_at AI199589 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI199589 /FEA=EST /DB_XREF=gi:3752195 /DB_XREF=est:qi57d04.x1 /CLONE=IMAGE:1860583 /UG=Hs.272814 hypothetical protein DKFZp434E1723 AI199589 PDX1 C-terminal inhibiting factor 1 PCIF1 63935 NM_022104 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 222046_at AI523895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI523895 /FEA=EST /DB_XREF=gi:4438030 /DB_XREF=est:tg97g03.x1 /CLONE=IMAGE:2116756 /UG=Hs.111801 arsenate resistance protein ARS2 AI523895 serrate, RNA effector molecule SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 222047_s_at AI523895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI523895 /FEA=EST /DB_XREF=gi:4438030 /DB_XREF=est:tg97g03.x1 /CLONE=IMAGE:2116756 /UG=Hs.111801 arsenate resistance protein ARS2 AI523895 serrate, RNA effector molecule SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 222048_at AA536000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA536000 /FEA=EST /DB_XREF=gi:2280253 /DB_XREF=est:nf95c09.s1 /CLONE=IMAGE:927664 /UG=Hs.20938 RNA binding motif, single stranded interacting protein 2 AA536000 crystallin, beta B2 pseudogene 1 CRYBB2P1 1416 NR_033733 /// NR_033734 222049_s_at AA908769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA908769 /FEA=EST /DB_XREF=gi:3048174 /DB_XREF=est:ol06a10.s1 /CLONE=IMAGE:1522650 /UG=Hs.76461 retinol-binding protein 4, interstitial AA908769 retinol binding protein 4, plasma RBP4 5950 NM_006744 /// XM_005270023 0001523 // retinoid metabolic process // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001654 // eye development // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from mutant phenotype /// 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007603 // phototransduction, visible light // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from direct assay /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0034633 // retinol transport // inferred by curator /// 0042572 // retinol metabolic process // inferred from mutant phenotype /// 0042574 // retinal metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048706 // embryonic skeletal system development // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0048807 // female genitalia morphogenesis // inferred from sequence or structural similarity /// 0050908 // detection of light stimulus involved in visual perception // inferred from electronic annotation /// 0051024 // positive regulation of immunoglobulin secretion // inferred from sequence or structural similarity /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0060065 // uterus development // inferred from sequence or structural similarity /// 0060068 // vagina development // inferred from sequence or structural similarity /// 0060157 // urinary bladder development // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from direct assay /// 0034632 // retinol transporter activity // inferred by curator /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 222050_at AI703341 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI703341 /FEA=EST /DB_XREF=gi:4991241 /DB_XREF=est:wd93b02.x1 /CLONE=IMAGE:2339115 /UG=Hs.52788 fragile X mental retardation, autosomal homolog 2 AI703341 222051_s_at AW139195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW139195 /FEA=EST /DB_XREF=gi:6143513 /DB_XREF=est:UI-H-BI1-aet-h-02-0-UI.s1 /CLONE=IMAGE:2720499 /UG=Hs.2331 E2F transcription factor 5, p130-binding AW139195 RP11-219B4.3 222052_at AA001552 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA001552 /FEA=EST /DB_XREF=gi:1437017 /DB_XREF=est:ze46c08.s1 /CLONE=IMAGE:362030 /UG=Hs.59839 ESTs, Weakly similar to CGHU7L collagen alpha 1(III) chain precursor H.sapiens AA001552 chromosome 19 open reading frame 54 C19orf54 284325 NM_198476 /// XM_005258776 /// XM_005258778 /// XM_006723151 /// XM_006723152 /// XM_006723153 222053_at AI497781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI497781 /FEA=EST /DB_XREF=gi:4389763 /DB_XREF=est:tm89c09.x1 /CLONE=IMAGE:2165296 /UG=Hs.274324 hypothetical protein FLJ11136 AI497781 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa TAF6L 10629 NM_006473 /// XM_005273714 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 222054_at BF511556 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF511556 /FEA=EST /DB_XREF=gi:11594854 /DB_XREF=est:UI-H-BI4-apq-g-05-0-UI.s1 /CLONE=IMAGE:3088328 /UG=Hs.33251 peptidylprolyl isomerase E (cyclophilin E) BF511556 peptidylprolyl isomerase E-like pseudogene PPIEL 728448 NR_003929 222055_at AA723370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA723370 /FEA=EST /DB_XREF=gi:2741077 /DB_XREF=est:zg73a01.s1 /CLONE=IMAGE:398952 /UG=Hs.279932 CGI-105 protein AA723370 fumarylacetoacetate hydrolase domain containing 2A /// fumarylacetoacetate hydrolase domain containing 2B /// fumarylacetoacetate hydrolase domain containing 2C, pseudogene FAHD2A /// FAHD2B /// FAHD2CP 51011 /// 151313 /// 729234 NM_016044 /// NM_199336 /// NR_003698 /// XM_005263892 /// XM_005263893 /// XM_006712560 /// XM_006712561 /// XM_006712562 /// XM_006712563 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222056_s_at AA723370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA723370 /FEA=EST /DB_XREF=gi:2741077 /DB_XREF=est:zg73a01.s1 /CLONE=IMAGE:398952 /UG=Hs.279932 CGI-105 protein AA723370 fumarylacetoacetate hydrolase domain containing 2A FAHD2A 51011 NM_016044 /// XM_006712560 /// XM_006712561 /// XM_006712562 /// XM_006712563 0008152 // metabolic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222057_at AW002578 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW002578 /FEA=EST /DB_XREF=gi:5849494 /DB_XREF=est:wu10g11.x1 /CLONE=IMAGE:2516612 /UG=Hs.326372 hypothetical protein MGC3731 AW002578 nucleolar protein 12 NOL12 79159 NM_024313 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222058_at AW194818 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW194818 /FEA=EST /DB_XREF=gi:6473756 /DB_XREF=est:xn31g09.x1 /CLONE=IMAGE:2695360 /UG=Hs.102737 goliath protein AW194818 ring finger protein 130 RNF130 55819 NM_001280801 /// NM_018434 /// XM_006714890 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222059_at BE676476 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE676476 /FEA=EST /DB_XREF=gi:10037007 /DB_XREF=est:7f30c11.x1 /CLONE=IMAGE:3296180 /UG=Hs.165983 hypothetical C2H2 zinc finger protein FLJ22504 BE676476 zinc finger protein 335 ZNF335 63925 NM_022095 /// XM_005260504 /// XM_005260506 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 222060_at AI357616 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI357616 /FEA=EST /DB_XREF=gi:4109237 /DB_XREF=est:qu20g08.x1 /CLONE=IMAGE:1965374 /UG=Hs.101651 Homo sapiens mRNA; cDNA DKFZp434C107 (from clone DKFZp434C107) AI357616 keratin 8 pseudogene 12 KRT8P12 90133 222061_at AA700015 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA700015 /FEA=EST /DB_XREF=gi:2702978 /DB_XREF=est:zi69c11.s1 /CLONE=IMAGE:436052 /UG=Hs.287995 Homo sapiens cDNA: FLJ23181 fis, clone LNG11094 AA700015 CD58 molecule CD58 965 NM_001144822 /// NM_001779 /// NR_026665 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0034113 // heterotypic cell-cell adhesion // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 2000484 // positive regulation of interleukin-8 secretion // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction 222062_at AI983115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI983115 /FEA=EST /DB_XREF=gi:5810334 /DB_XREF=est:wu18b02.x1 /CLONE=IMAGE:2517291 /UG=Hs.132781 class I cytokine receptor AI983115 interleukin 27 receptor, alpha IL27RA 9466 NM_004843 0002827 // positive regulation of T-helper 1 type immune response // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0048302 // regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0070106 // interleukin-27-mediated signaling pathway // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0045509 // interleukin-27 receptor activity // inferred from electronic annotation 222063_s_at AI991484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI991484 /FEA=EST /DB_XREF=gi:5838389 /DB_XREF=est:ws17c01.x1 /CLONE=IMAGE:2497440 /UG=Hs.152981 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 AI991484 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 CDS1 1040 NM_001263 /// XM_005262687 0006644 // phospholipid metabolic process // traceable author statement /// 0006657 // CDP-choline pathway // non-traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007602 // phototransduction // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from direct assay /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004142 // diacylglycerol cholinephosphotransferase activity // non-traceable author statement /// 0004605 // phosphatidate cytidylyltransferase activity // inferred from direct assay /// 0004605 // phosphatidate cytidylyltransferase activity // traceable author statement 222064_s_at AI093187 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI093187 /FEA=EST /DB_XREF=gi:3432163 /DB_XREF=est:qa98b04.x1 /CLONE=IMAGE:1694767 /UG=Hs.317403 hypothetical protein MGC2744 AI093187 alanyl-tRNA synthetase domain containing 1 /// prostaglandin E synthase 3 (cytosolic)-like /// PTGES3L-AARSD1 readthrough AARSD1 /// PTGES3L /// PTGES3L-AARSD1 80755 /// 100885848 /// 100885850 NM_001136042 /// NM_001142653 /// NM_001142654 /// NM_001261430 /// NM_001261434 /// NM_025267 0006412 // translation // inferred from electronic annotation /// 0006419 // alanyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0002196 // Ser-tRNA(Ala) hydrolase activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004813 // alanine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222065_s_at AI830227 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI830227 /FEA=EST /DB_XREF=gi:5450887 /DB_XREF=est:wj78g07.x1 /CLONE=IMAGE:2408988 /UG=Hs.83849 flightless I (Drosophila) homolog AI830227 flightless I homolog (Drosophila) FLII 2314 NM_001256264 /// NM_001256265 /// NM_002018 /// XM_005256555 /// XM_005256556 /// XM_005256558 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222066_at AA573523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA573523 /FEA=EST /DB_XREF=gi:2348051 /DB_XREF=est:nk99h04.s1 /CLONE=IMAGE:1028983 /UG=Hs.26395 erythrocyte membrane protein band 4.1-like 1 AA573523 222067_x_at AL353759 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL353759 /DEF=Human DNA sequence from clone RP1-221C16 on chromosome 6. Contains two genes for novel histone 4 family members, two genes for novel histone 1 family members, three genes for novel histone 2B family members, a gene for a novel histone 2A family me... /FEA=mRNA_10 /DB_XREF=gi:8745068 /UG=Hs.180779 H2B histone family, member B AL353759 histone cluster 1, H2bd HIST1H2BD 3017 NM_021063 /// NM_138720 /// XM_005249039 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 222068_s_at AW663632 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW663632 /FEA=EST /DB_XREF=gi:7456210 /DB_XREF=est:hj12a03.x1 /CLONE=IMAGE:2981548 /UG=Hs.285625 Homo sapiens mRNA; cDNA DKFZp434A119 (from clone DKFZp434A119) AW663632 dynein, axonemal, assembly factor 1 DNAAF1 123872 NM_178452 /// XM_006721129 /// XM_006721130 0001947 // heart looping // inferred from mutant phenotype /// 0003341 // cilium movement // inferred from mutant phenotype /// 0003356 // regulation of cilium beat frequency // inferred from mutant phenotype /// 0030324 // lung development // inferred from mutant phenotype /// 0035469 // determination of pancreatic left/right asymmetry // inferred from mutant phenotype /// 0036158 // outer dynein arm assembly // inferred from mutant phenotype /// 0036159 // inner dynein arm assembly // inferred from mutant phenotype /// 0044458 // motile cilium assembly // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred by curator /// 0060972 // left/right pattern formation // inferred from mutant phenotype /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0045502 // dynein binding // inferred from mutant phenotype 222069_s_at BF058311 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF058311 /FEA=EST /DB_XREF=gi:10812207 /DB_XREF=est:7k29d11.x1 /CLONE=IMAGE:3476804 /UG=Hs.180040 hypothetical protein FLJ22439 BF058311 0006325 // chromatin organization // inferred from mutant phenotype /// 0008104 // protein localization // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0031497 // chromatin assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 222070_at AW090043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW090043 /FEA=EST /DB_XREF=gi:6047387 /DB_XREF=est:xd01c05.x1 /CLONE=IMAGE:2592488 /UG=Hs.326464 Homo sapiens cDNA: FLJ21702 fis, clone COL09874 AW090043 DND microRNA-mediated repression inhibitor 1 DND1 373863 NM_194249 0006364 // rRNA processing // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0060965 // negative regulation of gene silencing by miRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from direct assay 222071_s_at BE552428 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE552428 /FEA=EST /DB_XREF=gi:9794120 /DB_XREF=est:hw26d04.x1 /CLONE=IMAGE:3184039 /UG=Hs.127648 hypothetical protein PRO2176 BE552428 solute carrier organic anion transporter family, member 4C1 SLCO4C1 353189 NM_180991 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 222072_at AW450360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450360 /FEA=EST /DB_XREF=gi:6991136 /DB_XREF=est:UI-H-BI3-akn-c-11-0-UI.s1 /CLONE=IMAGE:2734845 /UG=Hs.98834 ESTs AW450360 ADD3 antisense RNA 1 ADD3-AS1 100505933 NR_038943 222073_at AI694562 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI694562 /FEA=EST /DB_XREF=gi:4971902 /DB_XREF=est:wd72g08.x1 /CLONE=IMAGE:2337182 /UG=Hs.150318 ESTs AI694562 collagen, type IV, alpha 3 (Goodpasture antigen) COL4A3 1285 NM_000091 /// NM_031362 /// NM_031363 /// NM_031364 /// NM_031365 /// NM_031366 /// XM_005246275 /// XM_005246276 /// XM_005246277 /// XM_005246279 /// XM_005246280 /// XM_006712244 /// XM_006712245 /// XR_241280 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0072577 // endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005587 // collagen type IV trimer // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // traceable author statement /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // non-traceable author statement 222074_at AW614435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW614435 /FEA=EST /DB_XREF=gi:7319621 /DB_XREF=est:hg83c08.x1 /CLONE=IMAGE:2952206 /UG=Hs.78601 uroporphyrinogen decarboxylase AW614435 uroporphyrinogen decarboxylase UROD 7389 NM_000374 /// NR_036510 /// XM_005271169 /// XM_005271170 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // traceable author statement /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004853 // uroporphyrinogen decarboxylase activity // inferred from direct assay /// 0004853 // uroporphyrinogen decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 222075_s_at BE792072 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE792072 /FEA=EST /DB_XREF=gi:10213270 /DB_XREF=est:601581780F1 /CLONE=IMAGE:3936258 /UG=Hs.326705 Homo sapiens ornithine decarboxylase antizyme 3 (OAZ3), mRNA BE792072 ornithine decarboxylase antizyme 3 OAZ3 51686 NM_001134939 /// NM_016178 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0015847 // putrescine transport // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity /// 1902268 // negative regulation of polyamine transmembrane transport // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation /// 0015489 // putrescine transmembrane transporter activity // inferred from sequence or structural similarity /// 0071532 // ankyrin repeat binding // inferred from electronic annotation 222076_at BE222436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE222436 /FEA=EST /DB_XREF=gi:8909754 /DB_XREF=est:hv90h11.x1 /CLONE=IMAGE:3180741 /UG=Hs.799 diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) BE222436 heparin-binding EGF-like growth factor HBEGF 1839 NM_001945 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051545 // negative regulation of elastin biosynthetic process // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005615 // extracellular space // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // non-traceable author statement 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype 222077_s_at AU153848 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU153848 /FEA=EST /DB_XREF=gi:11015369 /DB_XREF=est:AU153848 /CLONE=NT2RP3004175 /UG=Hs.23900 GTPase activating protein AU153848 Rac GTPase activating protein 1 RACGAP1 29127 NM_001126103 /// NM_001126104 /// NM_013277 /// XM_005268811 /// XM_005268812 /// XM_005268813 /// XM_005268814 /// XM_005268815 /// XM_005268816 /// XM_006719359 /// XM_006719360 0000281 // mitotic cytokinesis // inferred from direct assay /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from direct assay /// 0000915 // actomyosin contractile ring assembly // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007108 // cytokinesis, initiation of separation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008272 // sulfate transport // inferred from direct assay /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051256 // spindle midzone assembly involved in mitosis // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay /// 0072686 // mitotic spindle // inferred from mutant phenotype /// 0097149 // centralspindlin complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0043015 // gamma-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from direct assay 222078_at BF110802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF110802 /FEA=EST /DB_XREF=gi:10940492 /DB_XREF=est:7n29e05.x1 /CLONE=IMAGE:3565929 /UG=Hs.284171 KIAA1535 protein BF110802 pyruvate kinase, liver and RBC PKLR 5313 NM_000298 /// NM_181871 /// XM_005245266 /// XM_006711386 /// XM_006726212 0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0042866 // pyruvate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222079_at BF739971 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF739971 /FEA=EST /DB_XREF=gi:12066647 /DB_XREF=est:7o41f07.x1 /CLONE=IMAGE:3576732 /UG=Hs.98416 ESTs BF739971 v-ets avian erythroblastosis virus E26 oncogene homolog ERG 2078 NM_001136154 /// NM_001136155 /// NM_001243428 /// NM_001243429 /// NM_001243432 /// NM_001243433 /// NM_001291391 /// NM_004449 /// NM_182918 /// NR_111949 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030154 // cell differentiation // not recorded 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 222080_s_at AW188134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188134 /FEA=EST /DB_XREF=gi:6462570 /DB_XREF=est:xj92g03.x1 /CLONE=IMAGE:2664724 /UG=Hs.106346 retinoic acid repressible protein AW188134 /// sirtuin 5 RP1-223E5.4 /// SIRT5 23408 NM_001193267 /// NM_001242827 /// NM_012241 /// NM_031244 /// XM_005248967 /// XM_005248968 /// XM_005248969 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0036047 // peptidyl-lysine demalonylation // inferred from direct assay /// 0036048 // protein desuccinylation // inferred from direct assay /// 0036049 // peptidyl-lysine desuccinylation // inferred from direct assay /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036054 // protein-malonyllysine demalonylase activity // inferred from direct assay /// 0036055 // protein-succinyllysine desuccinylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 222081_at AW188134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW188134 /FEA=EST /DB_XREF=gi:6462570 /DB_XREF=est:xj92g03.x1 /CLONE=IMAGE:2664724 /UG=Hs.106346 retinoic acid repressible protein AW188134 /// sirtuin 5 RP1-223E5.4 /// SIRT5 23408 NM_001193267 /// NM_001242827 /// NM_012241 /// NM_031244 /// XM_005248967 /// XM_005248968 /// XM_005248969 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0036047 // peptidyl-lysine demalonylation // inferred from direct assay /// 0036048 // protein desuccinylation // inferred from direct assay /// 0036049 // peptidyl-lysine desuccinylation // inferred from direct assay /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036054 // protein-malonyllysine demalonylase activity // inferred from direct assay /// 0036055 // protein-succinyllysine desuccinylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from direct assay 222082_at AI568395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI568395 /FEA=EST /DB_XREF=gi:4531769 /DB_XREF=est:th13g04.x1 /CLONE=IMAGE:2118198 /UG=Hs.104640 HIV-1 inducer of short transcripts binding protein AI568395 zinc finger and BTB domain containing 7A ZBTB7A 51341 NM_015898 /// XM_005259570 /// XM_005259571 /// XM_005259572 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 222083_at AW024233 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW024233 /FEA=EST /DB_XREF=gi:5877763 /DB_XREF=est:wv02c01.x1 /CLONE=IMAGE:2528352 /UG=Hs.18508 putative glycine-N-acyltransferase AW024233 glycine-N-acyltransferase GLYAT 10249 NM_005838 /// NM_201648 0006544 // glycine metabolic process // inferred from sequence or structural similarity /// 0006637 // acyl-CoA metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0032787 // monocarboxylic acid metabolic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0047961 // glycine N-acyltransferase activity // inferred from electronic annotation /// 0047962 // glycine N-benzoyltransferase activity // inferred from sequence or structural similarity 222084_s_at AI333707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI333707 /FEA=EST /DB_XREF=gi:4070266 /DB_XREF=est:qp93c06.x1 /CLONE=IMAGE:1930570 /UG=Hs.112049 SET binding factor 1 AI333707 SET binding factor 1 SBF1 6305 NM_002972 /// XM_005261931 /// XM_005261932 /// XM_005261934 /// XM_005261935 0006470 // protein dephosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 222085_at AW452357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW452357 /FEA=EST /DB_XREF=gi:6993133 /DB_XREF=est:UI-H-BI3-alr-d-03-0-UI.s1 /CLONE=IMAGE:3068213 /UG=Hs.27373 Homo sapiens mRNA; cDNA DKFZp564O1763 (from clone DKFZp564O1763) AW452357 222086_s_at AI191771 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI191771 /FEA=EST /DB_XREF=gi:3742980 /DB_XREF=est:qd62f02.x1 /CLONE=IMAGE:1734075 /UG=Hs.29764 wingless-type MMTV integration site family, member 6 AI191771 wingless-type MMTV integration site family, member 6 WNT6 7475 NM_006522 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0009798 // axis specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0070172 // positive regulation of tooth mineralization // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0072079 // nephron tubule formation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation 0005109 // frizzled binding // not recorded 222087_at AW451806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW451806 /FEA=EST /DB_XREF=gi:6992582 /DB_XREF=est:UI-H-BI3-alk-c-10-0-UI.s1 /CLONE=IMAGE:2737146 /UG=Hs.32458 ESTs AW451806 microRNA 1204 /// Pvt1 oncogene (non-protein coding) MIR1204 /// PVT1 5820 /// 100302185 NR_003367 /// NR_031609 222088_s_at AA778684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA778684 /FEA=EST /DB_XREF=gi:2838015 /DB_XREF=est:af87g07.s1 /CLONE=1049052 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 AA778684 solute carrier family 2 (facilitated glucose transporter), member 14 /// solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A14 /// SLC2A3 6515 /// 144195 NM_001286233 /// NM_001286234 /// NM_001286235 /// NM_001286236 /// NM_001286237 /// NM_006931 /// NM_153449 /// XM_005253315 /// XM_005253317 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 222089_s_at BF508774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF508774 /FEA=EST /DB_XREF=gi:11592072 /DB_XREF=est:UI-H-BI4-aoq-f-10-0-UI.s1 /CLONE=IMAGE:3085962 /UG=Hs.101414 KIAA0557 protein BF508774 chromosome 16 open reading frame 71 C16orf71 146562 NM_139170 /// XM_005255144 /// XM_006720851 222090_at BF509069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF509069 /FEA=EST /DB_XREF=gi:11592367 /DB_XREF=est:UI-H-BI4-aou-b-03-0-UI.s1 /CLONE=IMAGE:3086140 /UG=Hs.27262 Homo sapiens clone 25110 mRNA sequence BF509069 NDUFB2 antisense RNA 1 NDUFB2-AS1 100134713 NR_024454 222091_at BE550384 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE550384 /FEA=EST /DB_XREF=gi:9792076 /DB_XREF=est:7a22h11.x1 /CLONE=IMAGE:3219525 /UG=Hs.272891 hippocalcin-like protein 4 BE550384 hippocalcin like 4 HPCAL4 51440 NM_001282396 /// NM_001282397 /// NM_016257 0007417 // central nervous system development // traceable author statement 0005622 // intracellular // inferred from direct assay 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222092_at BF116199 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF116199 /FEA=EST /DB_XREF=gi:10985675 /DB_XREF=est:7n78h08.x1 /CLONE=IMAGE:3571046 /UG=Hs.155693 protein tyrosine phosphatase, non-receptor type 21 BF116199 protein tyrosine phosphatase, non-receptor type 21 PTPN21 11099 NM_007039 /// XM_005267287 /// XM_006720011 0006470 // protein dephosphorylation // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222093_s_at BF223045 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF223045 /FEA=EST /DB_XREF=gi:11130222 /DB_XREF=est:7q28a07.x1 /CLONE=IMAGE:3699373 /UG=Hs.118282 Homo sapiens mRNA for PAPA-1, complete cds BF223045 INO80 complex subunit B INO80B 83444 NM_031288 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222094_at AI580112 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI580112 /FEA=EST /DB_XREF=gi:4564488 /DB_XREF=est:tk16e05.x1 /CLONE=IMAGE:2151200 /UG=Hs.326067 hypothetical protein MGC5178 AI580112 sulfotransferase 1A3/1A4-like /// structure-specific endonuclease subunit SLX1-like /// SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) /// SLX1A-SULT1A3 readthrough (NMD candidate) /// SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 /// sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 LOC101929857 /// LOC101929864 /// SLX1A /// SLX1A-SULT1A3 /// SLX1B /// SULT1A3 /// SULT1A4 6818 /// 79008 /// 445329 /// 548593 /// 100526830 /// 101929857 /// 101929864 NM_001014999 /// NM_001015000 /// NM_001017387 /// NM_001017389 /// NM_001017390 /// NM_001017391 /// NM_003166 /// NM_024044 /// NM_177552 /// NM_178044 /// NR_037608 /// XM_005276506 /// XM_005276507 /// XM_006726621 /// XM_006726622 /// XM_006726623 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0010792 // DNA double-strand break processing involved in repair via single-strand annealing // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0033557 // Slx1-Slx4 complex // inferred from direct assay 0004062 // aryl sulfotransferase activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008146 // sulfotransferase activity // inferred from direct assay /// 0008821 // crossover junction endodeoxyribonuclease activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222095_s_at AW450345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW450345 /FEA=EST /DB_XREF=gi:6991121 /DB_XREF=est:UI-H-BI3-akn-b-08-0-UI.s1 /CLONE=IMAGE:2734791 /UG=Hs.13999 KIAA0700 protein AW450345 family with sequence similarity 163, member A FAM163A 148753 NM_173509 /// XM_005244913 /// XM_006711174 /// XM_006711175 /// XM_006711176 /// XM_006711177 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222096_x_at BF056462 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF056462 /FEA=EST /DB_XREF=gi:10810358 /DB_XREF=est:7k05d12.x1 /CLONE=IMAGE:3443398 /UG=Hs.300683 Homo sapiens cDNA FLJ12825 fis, clone NT2RP2002800 BF056462 222097_at AI733248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI733248 /FEA=EST /DB_XREF=gi:5054361 /DB_XREF=est:oo58b11.x5 /CLONE=IMAGE:1570365 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) AI733248 222098_s_at AI733248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI733248 /FEA=EST /DB_XREF=gi:5054361 /DB_XREF=est:oo58b11.x5 /CLONE=IMAGE:1570365 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) AI733248 222099_s_at AW593859 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW593859 /FEA=EST /DB_XREF=gi:7281117 /DB_XREF=est:hg26a04.x1 /CLONE=IMAGE:2946702 /UG=Hs.8258 DKFZP434D1335 protein AW593859 LSM14A, SCD6 homolog A (S. cerevisiae) LSM14A 26065 NM_001114093 /// NM_015578 /// XM_005258719 /// XM_005258720 /// XM_005258721 /// XM_005276948 /// XM_005276949 /// XM_005276950 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0039529 // RIG-I signaling pathway // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222100_at AV650427 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV650427 /FEA=EST /DB_XREF=gi:9871441 /DB_XREF=est:AV650427 /CLONE=GLCCEF11 /UG=Hs.75183 cytochrome P450, subfamily IIE (ethanol-inducible) AV650427 222101_s_at BF222893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF222893 /FEA=EST /DB_XREF=gi:11130070 /DB_XREF=est:7q24f08.x1 /CLONE=IMAGE:3699231 /UG=Hs.9658 hypothetical protein FLJ11790 BF222893 dachsous cadherin-related 1 DCHS1 8642 NM_003737 /// NM_024542 /// XM_005253207 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0035329 // hippo signaling // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 222102_at NM_000847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:NM_000847.1 /DEF=Homo sapiens glutathione S-transferase A3 (GSTA3), mRNA. /FEA=CDS /GEN=GSTA3 /PROD=glutathione S-transferase A3 /DB_XREF=gi:11464996 /UG=Hs.102484 glutathione S-transferase A3 /FL=gb:NM_000847.1 NM_000847 glutathione S-transferase alpha 3 GSTA3 2940 NM_000847 /// XM_006715072 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 222103_at AI434345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI434345 /FEA=EST /DB_XREF=gi:4295529 /DB_XREF=est:ti48b06.x1 /CLONE=IMAGE:2133683 /UG=Hs.36908 activating transcription factor 1 /FL=gb:NM_005171.1 AI434345 activating transcription factor 1 ATF1 466 NM_005171 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 222104_x_at AI569458 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI569458 /FEA=EST /DB_XREF=gi:4532832 /DB_XREF=est:tn87c02.x1 /CLONE=IMAGE:2176514 /UG=Hs.90304 general transcription factor IIH, polypeptide 3 (34kD subunit) /FL=gb:NM_001516.1 AI569458 general transcription factor IIH, polypeptide 3, 34kDa GTF2H3 2967 NM_001271866 /// NM_001271867 /// NM_001271868 /// NM_001516 /// XM_005253568 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006412 // translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay 0003684 // damaged DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004672 // protein kinase activity // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 222105_s_at AA452565 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA452565 /FEA=EST /DB_XREF=gi:2166234 /DB_XREF=est:zx35g11.s1 /CLONE=IMAGE:788516 /UG=Hs.22937 I-kappa-B-interacting Ras-like protein 2 /FL=gb:AF229840.1 AA452565 NFKB inhibitor interacting Ras-like 2 NKIRAS2 28511 NM_001001349 /// NM_001144927 /// NM_001144928 /// NM_001144929 /// NM_017595 /// XM_005257251 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 222106_at AL133396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133396 /DEF=Human DNA sequence from clone RP5-1068H6 on chromosome 20q11.1-11.23. Contains a pseudogene similar to IDI1 (isopentenyl-diphosphate delta isomerase), the gene for the prion protein like doppel protein, the PRNP gene for prion protein (p27-30) (Cr... /FEA=mRNA_1 /DB_XREF=gi:6562003 /UG=Hs.121281 prion gene complex, downstream /FL=gb:NM_012409.1 AL133396 prion protein 2 (dublet) PRND 23627 NM_012409 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005507 // copper ion binding // inferred from electronic annotation 222107_x_at BE312985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE312985 /FEA=EST /DB_XREF=gi:9132352 /DB_XREF=est:601150246F1 /CLONE=IMAGE:3503003 /UG=Hs.93605 leucine zipper, putative tumor suppressor 1 /FL=gb:AF123658.1 BE312985 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 222108_at AC004010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004010 /DEF=Human BAC clone GS1-99H8 /FEA=CDS /DB_XREF=gi:2781385 /UG=Hs.121520 Human BAC clone GS1-99H8 AC004010 adhesion molecule with Ig-like domain 2 AMIGO2 347902 NM_001143668 /// NM_181847 /// XM_005268837 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 222109_at AA558583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA558583 /FEA=EST /DB_XREF=gi:2329060 /DB_XREF=est:nk38h06.s1 /CLONE=IMAGE:1015835 /UG=Hs.288826 Homo sapiens cDNA FLJ12263 fis, clone MAMMA1001590 AA558583 guanine nucleotide binding protein-like 3 (nucleolar)-like GNL3L 54552 NM_001184819 /// NM_019067 0006184 // GTP catabolic process // not recorded /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222110_at AW008921 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW008921 /FEA=EST /DB_XREF=gi:5857699 /DB_XREF=est:ws75a03.x1 /CLONE=IMAGE:2503756 /UG=Hs.13138 Homo sapiens, clone IMAGE:3448343, mRNA, partial cds AW008921 SUMO1/sentrin specific peptidase 5 SENP5 205564 NM_152699 /// XM_005269310 /// XM_005269311 /// XM_005269312 0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 222111_at AU145293 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145293 /FEA=EST /DB_XREF=gi:11006814 /DB_XREF=est:AU145293 /CLONE=HEMBA1004405 /UG=Hs.61773 Homo sapiens cDNA FLJ11648 fis, clone HEMBA1004405 AU145293 family with sequence similarity 63, member B FAM63B 54629 NM_001040450 /// NM_001040453 /// NM_019092 222112_at AV710549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV710549 /FEA=EST /DB_XREF=gi:10729178 /DB_XREF=est:AV710549 /CLONE=CuAAGC04 /UG=Hs.147176 epidermal growth factor receptor substrate EPS15R AV710549 epidermal growth factor receptor pathway substrate 15-like 1 EPS15L1 58513 NM_001258374 /// NM_001258375 /// NM_001258376 /// NM_021235 /// NR_047665 /// NR_047666 /// XM_006722823 /// XM_006722824 /// XM_006722825 /// XM_006722826 /// XM_006722827 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222113_s_at AV710549 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV710549 /FEA=EST /DB_XREF=gi:10729178 /DB_XREF=est:AV710549 /CLONE=CuAAGC04 /UG=Hs.147176 epidermal growth factor receptor substrate EPS15R AV710549 epidermal growth factor receptor pathway substrate 15-like 1 EPS15L1 58513 NM_001258374 /// NM_001258375 /// NM_001258376 /// NM_021235 /// NR_047665 /// NR_047666 /// XM_006722823 /// XM_006722824 /// XM_006722825 /// XM_006722826 /// XM_006722827 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222114_x_at BE409994 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE409994 /FEA=EST /DB_XREF=gi:9346444 /DB_XREF=est:601299404F1 /CLONE=IMAGE:3629592 /UG=Hs.326464 Homo sapiens cDNA: FLJ21702 fis, clone COL09874 BE409994 WD repeat domain 55 WDR55 54853 NM_017706 /// XM_005268469 /// XM_005268471 /// XM_006714788 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0060965 // negative regulation of gene silencing by miRNA // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from direct assay 222115_x_at BC003693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003693.1 /DEF=Homo sapiens, Similar to RIKEN cDNA 3930401K13 gene, clone IMAGE:3454556, mRNA, partial cds. /FEA=mRNA /PROD=Similar to RIKEN cDNA 3930401K13 gene /DB_XREF=gi:13277567 /UG=Hs.90998 KIAA0128 protein; septin 2 BC003693 glyoxylate reductase 1 homolog (Arabidopsis) GLYR1 84656 NM_032569 /// XM_005255637 /// XM_005255638 /// XM_005255639 /// XM_005255640 /// XR_243321 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 222116_s_at AL157485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL157485.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762O207 (from clone DKFZp762O207). /FEA=mRNA /DB_XREF=gi:7018528 /UG=Hs.91973 hypothetical protein AL157485 TBC1 domain family, member 16 TBC1D16 125058 NM_001271844 /// NM_001271845 /// NM_001271846 /// NM_019020 /// XM_005257049 /// XM_005257050 /// XM_005257052 /// XM_006721694 /// XM_006721695 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation 222117_s_at AF131745 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131745.1 /DEF=Homo sapiens clone 25110 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406559 /UG=Hs.27262 Homo sapiens clone 25110 mRNA sequence AF131745 aarF domain containing kinase 2 ADCK2 90956 NM_052853 /// XM_006716170 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 222118_at AK023669 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023669.1 /DEF=Homo sapiens cDNA FLJ13607 fis, clone PLACE1010624. /FEA=mRNA /DB_XREF=gi:10435661 /UG=Hs.283532 uncharacterized bone marrow protein BM039 AK023669 centromere protein N CENPN 55839 NM_001100624 /// NM_001100625 /// NM_001270473 /// NM_001270474 /// NM_018455 /// XM_006721236 0000278 // mitotic cell cycle // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0034508 // centromere complex assembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 222119_s_at AL117620 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117620.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564K2364 (from clone DKFZp564K2364); partial cds. /FEA=mRNA /GEN=DKFZp564K2364 /PROD=hypothetical protein /DB_XREF=gi:5912200 /UG=Hs.284289 vitiligo-associated protein VIT-1 AL117620 F-box protein 11 FBXO11 80204 NM_001190274 /// NM_012167 /// NM_018693 /// NM_025133 /// XM_005264572 /// XM_005264573 /// XM_005264574 0006464 // cellular protein modification process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0035246 // peptidyl-arginine N-methylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016274 // protein-arginine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222120_at BC000016 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000016.1 /DEF=Homo sapiens, clone IMAGE:3508146, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3508146) /DB_XREF=gi:12652552 /UG=Hs.132227 Homo sapiens, clone IMAGE:3508146, mRNA, partial cds BC000016 zinc finger protein 764 ZNF764 92595 NM_001172679 /// NM_033410 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222121_at AU118383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU118383 /FEA=EST /DB_XREF=gi:10933427 /DB_XREF=est:AU118383 /CLONE=HEMBA1003482 /UG=Hs.240845 DKFZP434D146 protein AU118383 Rho guanine nucleotide exchange factor (GEF) 26 ARHGEF26 26084 NM_001251962 /// NM_001251963 /// NM_015595 /// XM_005247324 /// XM_006724998 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 222122_s_at BG403671 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG403671 /FEA=EST /DB_XREF=gi:13297119 /DB_XREF=est:602419393F1 /CLONE=IMAGE:4526326 /UG=Hs.16411 hypothetical protein LOC57187 BG403671 THO complex 2 THOC2 57187 NM_001081550 /// NM_020449 /// XM_005262447 /// XM_005262450 /// XM_006724767 /// XM_006724768 /// XM_006724769 /// XM_006724770 /// XM_006724771 /// XM_006724772 /// XM_006724773 /// XR_430547 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from direct assay /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222123_s_at AK021881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021881.1 /DEF=Homo sapiens cDNA FLJ11819 fis, clone HEMBA1006426. /FEA=mRNA /DB_XREF=gi:10433167 /UG=Hs.284256 hypothetical protein FLJ14033 similar to hypoxia inducible factor 3, alpha subunit AK021881 hypoxia inducible factor 3, alpha subunit HIF3A 64344 NM_022462 /// NM_152794 /// NM_152795 /// NM_152796 /// XM_005259152 /// XM_005259153 /// XM_005259154 /// XM_005259155 /// XM_005259156 /// XM_006723324 /// XM_006723325 /// XR_243952 0001666 // response to hypoxia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 222124_at AK021881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021881.1 /DEF=Homo sapiens cDNA FLJ11819 fis, clone HEMBA1006426. /FEA=mRNA /DB_XREF=gi:10433167 /UG=Hs.284256 hypothetical protein FLJ14033 similar to hypoxia inducible factor 3, alpha subunit AK021881 hypoxia inducible factor 3, alpha subunit HIF3A 64344 NM_022462 /// NM_152794 /// NM_152795 /// NM_152796 /// XM_005259152 /// XM_005259153 /// XM_005259154 /// XM_005259155 /// XM_005259156 /// XM_006723324 /// XM_006723325 /// XR_243952 0001666 // response to hypoxia // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 222125_s_at BC000580 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000580.1 /DEF=Homo sapiens, clone IMAGE:3162218, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3162218) /DB_XREF=gi:12653606 /UG=Hs.5014 hypothetical protein FLJ20262 BC000580 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) P4HTM 54681 NM_017732 /// NM_177938 /// NM_177939 /// XR_245139 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 222126_at AI247494 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI247494 /FEA=EST /DB_XREF=gi:3842891 /DB_XREF=est:qh56e02.x1 /CLONE=IMAGE:1848698 /UG=Hs.251678 HIV-1 Rev binding protein-like AI247494 ArfGAP with FG repeats 2 AGFG2 3268 NM_006076 /// XM_005250306 /// XM_006715958 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222127_s_at AK023461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023461.1 /DEF=Homo sapiens cDNA FLJ13399 fis, clone PLACE1001395. /FEA=mRNA /DB_XREF=gi:10435404 /UG=Hs.306648 Homo sapiens cDNA FLJ13399 fis, clone PLACE1001395 AK023461 exocyst complex component 1 EXOC1 55763 NM_001024924 /// NM_018261 /// NM_178237 /// XM_005265747 /// XM_005265748 /// XM_005265750 /// XM_006714042 /// XM_006714043 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000145 // exocyst // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222128_at U80764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:U80764.1 /DEF=Human EST clone 122887 mariner transposon Hsmar1 sequence. /FEA=mRNA /DB_XREF=gi:2231367 /UG=Hs.132967 Human EST clone 122887 mariner transposon Hsmar1 sequence U80764 NOP2/Sun domain family, member 6 NSUN6 221078 NM_182543 /// XM_005252394 /// XM_005252397 /// XM_005252398 /// XM_005252399 /// XM_006717400 /// XR_428678 0032259 // methylation // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 222129_at AK026155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026155.1 /DEF=Homo sapiens cDNA: FLJ22502 fis, clone HRC11383. /FEA=mRNA /DB_XREF=gi:10438915 /UG=Hs.298140 Homo sapiens cDNA: FLJ22502 fis, clone HRC11383 AK026155 family with sequence similarity 134, member A FAM134A 79137 NM_024293 /// XM_005246848 /// XM_005246849 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222130_s_at AK024635 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024635.1 /DEF=Homo sapiens cDNA: FLJ20982 fis, clone ADSU02018, highly similar to AF093415 Homo sapiens cell division protein FtsJ (FJH1) mRNA. /FEA=mRNA /DB_XREF=gi:10436956 /UG=Hs.279877 cell division protein FtsJ AK024635 FtsJ RNA methyltransferase homolog 2 (E. coli) FTSJ2 29960 NM_013393 /// NM_177442 0001510 // RNA methylation // inferred from electronic annotation /// 0006364 // rRNA processing // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0031167 // rRNA methylation // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008650 // rRNA (uridine-2'-O-)-methyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 222131_x_at BC004327 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC004327.1 /DEF=Homo sapiens, clone IMAGE:3629896, mRNA, partial cds. /FEA=mRNA /PROD=Unknown (protein for IMAGE:3629896) /DB_XREF=gi:13279244 /UG=Hs.21497 Homo sapiens, clone IMAGE:3629896, mRNA, partial cds BC004327 ras homolog family member T2 RHOT2 89941 NM_138769 /// XM_005255660 /// XM_005255661 /// XM_005255662 /// XM_005255663 /// XM_005255664 /// XM_006720970 /// XM_006720971 /// XM_006720972 /// XM_006720973 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from mutant phenotype /// 0047497 // mitochondrion transport along microtubule // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222132_s_at AJ278150 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ278150.1 /DEF=Homo sapiens mRNA for putative lipid kinase. /FEA=mRNA /PROD=putative lipid kinase /DB_XREF=gi:8250242 /UG=Hs.260238 hypothetical protein FLJ10842 AJ278150 acylglycerol kinase AGK 55750 NM_018238 /// XM_005250021 /// XM_005250023 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation /// 0046834 // lipid phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001727 // lipid kinase activity // inferred from electronic annotation /// 0001729 // ceramide kinase activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047620 // acylglycerol kinase activity // inferred from electronic annotation 222133_s_at AK022280 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022280.1 /DEF=Homo sapiens cDNA FLJ12218 fis, clone MAMMA1001075, moderately similar to Homo sapiens CGI-72 protein mRNA. /FEA=mRNA /DB_XREF=gi:10433640 /UG=Hs.288435 Homo sapiens cDNA FLJ12218 fis, clone MAMMA1001075, moderately similar to Homo sapiens CGI-72 protein mRNA AK022280 PHD finger protein 20-like 1 PHF20L1 51105 NM_001277196 /// NM_016018 /// NM_024878 /// NM_032205 /// NM_198513 /// XM_005250930 /// XM_005250931 /// XM_005250932 /// XM_005250933 /// XM_005250934 /// XM_005250935 /// XM_005250936 /// XM_005250937 /// XM_005250938 /// XM_005250939 /// XM_005250940 /// XM_005250942 /// XM_006716572 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222134_at AL050350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL050350 /DEF=Human DNA sequence from clone 261K5 on chromosome 6q21-22.1. Contains the 3 part of the gene for a novel organic cation transporter (BAC ORF RG331P03), the DDO gene for D-aspartate oxidase (EC 1.4.3.1), ESTs, STSs, GSSs and two putative CpG islands /FEA=mRNA_2 /DB_XREF=gi:5763740 /UG=Hs.174441 D-aspartate oxidase AL050350 D-aspartate oxidase DDO 8528 NM_003649 /// NM_004032 0006531 // aspartate metabolic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0007320 // insemination // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0019478 // D-amino acid catabolic process // inferred from direct assay /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005777 // peroxisome // non-traceable author statement 0003884 // D-amino-acid oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008445 // D-aspartate oxidase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay 222135_at AK022663 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022663.1 /DEF=Homo sapiens cDNA FLJ12601 fis, clone NT2RM4001414. /FEA=mRNA /DB_XREF=gi:10434187 /UG=Hs.288549 Homo sapiens cDNA FLJ12601 fis, clone NT2RM4001414 AK022663 zinc finger protein 814 ZNF814 730051 NM_001144989 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 222136_x_at AK022905 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022905.1 /DEF=Homo sapiens cDNA FLJ12843 fis, clone NT2RP2003293. /FEA=mRNA /DB_XREF=gi:10434566 /UG=Hs.224410 Homo sapiens cDNA FLJ12843 fis, clone NT2RP2003293 AK022905 zinc finger protein 43 /// zinc finger protein 729 ZNF43 /// ZNF729 7594 /// 100287226 NM_001242680 /// NM_001256648 /// NM_001256649 /// NM_001256650 /// NM_001256651 /// NM_001256653 /// NM_001256654 /// NM_003423 /// XM_005260057 /// XM_006722601 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 222137_at AK023399 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023399.1 /DEF=Homo sapiens cDNA FLJ13337 fis, clone OVARC1001880. /FEA=mRNA /DB_XREF=gi:10435320 /UG=Hs.181780 hypothetical protein FLJ20241 AK023399 coiled-coil and C2 domain containing 1A CC2D1A 54862 NM_017721 /// XM_005259972 /// XM_005259973 /// XM_005259974 /// XM_005259975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype 222138_s_at AF158978 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF158978.1 /DEF=Homo sapiens WDR13-like mRNA sequence. /FEA=mRNA /DB_XREF=gi:8886053 /UG=Hs.12142 WD repeat domain 13 AF158978 WD repeat domain 13 WDR13 64743 NM_001166426 /// NM_017883 /// NR_029427 /// XM_006724539 /// XM_006724540 /// XM_006724541 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 222139_at AI765383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI765383 /FEA=EST /DB_XREF=gi:5231892 /DB_XREF=est:wi74d08.x1 /CLONE=IMAGE:2399055 /UG=Hs.147710 KIAA1466 protein AI765383 endogenous retrovirus group 3, member 2 ERV3-2 57612 0015074 // DNA integration // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from electronic annotation 222140_s_at AK021758 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021758.1 /DEF=Homo sapiens cDNA FLJ11696 fis, clone HEMBA1005029, highly similar to Homo sapiens CGI-13 protein mRNA. /FEA=mRNA /DB_XREF=gi:10433004 /UG=Hs.16085 putative G-protein coupled receptor AK021758 G protein-coupled receptor 89A /// G protein-coupled receptor 89B GPR89A /// GPR89B 51463 /// 653519 NM_001097612 /// NM_001097613 /// NM_001097616 /// NM_016334 /// NR_036541 /// XM_005277401 /// XM_005277402 /// XM_005277404 /// XM_006711377 /// XM_006711378 /// XM_006711379 /// XM_006711492 /// XM_006711493 /// XM_006711494 /// XR_248599 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044070 // regulation of anion transport // inferred from direct assay /// 0051452 // intracellular pH reduction // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0008308 // voltage-gated anion channel activity // inferred from direct assay 222141_at AK024369 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024369.1 /DEF=Homo sapiens cDNA FLJ14307 fis, clone PLACE3000158. /FEA=mRNA /DB_XREF=gi:10436739 /UG=Hs.181341 Homo sapiens cDNA FLJ14307 fis, clone PLACE3000158 AK024369 kelch-like family member 22 KLHL22 84861 NM_032775 /// NR_033825 /// XM_006724342 /// XM_006724343 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222142_at AK024212 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024212.1 /DEF=Homo sapiens cDNA FLJ14150 fis, clone MAMMA1003026, highly similar to Homo sapiens HSPC057 mRNA. /FEA=mRNA /DB_XREF=gi:10436534 /UG=Hs.18827 KIAA0849 protein AK024212 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 222143_s_at AY007098 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AY007098.1 /DEF=Homo sapiens clone TCCCIA00183 mRNA sequence. /FEA=mRNA /DB_XREF=gi:9955989 /UG=Hs.27556 hypothetical protein FLJ22405 AY007098 myotubularin related protein 14 MTMR14 64419 NM_001077525 /// NM_001077526 /// NM_022485 /// XM_005265400 /// XR_245152 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 222144_at AA909345 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA909345 /FEA=EST /DB_XREF=gi:3048750 /DB_XREF=est:om09h10.s1 /CLONE=IMAGE:1540579 /UG=Hs.130411 KIAA1405 protein AA909345 kinesin family member 17 KIF17 57576 NM_001122819 /// NM_001287212 /// NM_020816 /// XM_005245950 /// XM_005245951 /// XR_241202 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 222145_at AK027225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027225.1 /DEF=Homo sapiens cDNA: FLJ23572 fis, clone LNG12403. /FEA=mRNA /DB_XREF=gi:10440306 /UG=Hs.201593 Homo sapiens cDNA: FLJ23572 fis, clone LNG12403 AK027225 222146_s_at AK026674 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026674.1 /DEF=Homo sapiens cDNA: FLJ23021 fis, clone LNG01014, highly similar to HUMSEF21B Human SEF2-1B protein (SEF2-1B) mRNA. /FEA=mRNA /DB_XREF=gi:10439577 /UG=Hs.326198 transcription factor 4 AK026674 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 222147_s_at AL133519 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133519 /DEF=Human DNA sequence from clone RP11-122O1 on chromosome 20 Contains a novel gene encoding a protein orthologous to the mouse vesicular inhibitory amino acid transporter (VIAAT), a novel gene similar to the yeast actin-like protein ARP5, 3 CpG islan... /FEA=CDS /DB_XREF=gi:10045268 /UG=Hs.302092 Human DNA sequence from clone RP11-122O1 on chromosome 20 Contains a novel gene encoding a protein orthologous to the mouse vesicular inhibitory amino acid transporter (VIAAT), a novel gene similar to the yeast actin-like protein ARP5, 3 CpG islands, ESTs AL133519 ARP5 actin-related protein 5 homolog (yeast) ACTR5 79913 NM_024855 /// XM_005260554 /// XM_005260555 /// XM_005260556 /// XM_005260557 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222148_s_at BF688108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF688108 /FEA=EST /DB_XREF=gi:11973516 /DB_XREF=est:602067332F1 /CLONE=IMAGE:4066422 /UG=Hs.14202 hypothetical protein FLJ11040 BF688108 ras homolog family member T1 RHOT1 55288 NM_001033566 /// NM_001033567 /// NM_001033568 /// NM_001288754 /// NM_001288755 /// NM_001288758 /// NM_018307 /// NR_110083 /// XM_005257996 /// XM_006721968 /// XM_006721969 /// XM_006721970 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from mutant phenotype /// 0047497 // mitochondrion transport along microtubule // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222149_x_at AL137398 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137398.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434K052 (from clone DKFZp434K052). /FEA=mRNA /DB_XREF=gi:6807944 /UG=Hs.169639 Homo sapiens mRNA; cDNA DKFZp434K052 (from clone DKFZp434K052) AL137398 golgin A8 family, member C, pseudogene /// golgin A8 family, member D, pseudogene /// golgin A8 family, member E, pseudogene /// golgin A8 family, member F /// golgin A8 family, member G GOLGA8CP /// GOLGA8DP /// GOLGA8EP /// GOLGA8F /// GOLGA8G 283768 /// 390535 /// 729786 /// 100132565 /// 100132979 NM_001012420 /// NM_001012423 /// NM_001012452 /// NM_001164328 /// NR_027407 /// NR_027411 /// NR_033350 /// NR_033351 /// NR_033352 /// NR_033353 0005794 // Golgi apparatus // inferred from electronic annotation 222150_s_at AK026747 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026747.1 /DEF=Homo sapiens cDNA: FLJ23094 fis, clone LNG07379, highly similar to HST000007 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 293605. /FEA=mRNA /DB_XREF=gi:10439670 /UG=Hs.12969 hypothetical protein AK026747 gamma-secretase activating protein GSAP 54103 NM_017439 /// XM_005250446 /// XM_005250448 /// XM_005250449 /// XM_005250450 /// XR_242248 0030162 // regulation of proteolysis // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from electronic annotation /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay 222151_s_at AK023738 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023738.1 /DEF=Homo sapiens cDNA FLJ13676 fis, clone PLACE1011922, weakly similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. /FEA=mRNA /DB_XREF=gi:10435760 /UG=Hs.300876 hypothetical protein FLJ13386 AK023738 centrosomal protein 63kDa CEP63 80254 NM_001042383 /// NM_001042384 /// NM_001042400 /// NM_025180 /// XM_005247795 /// XM_005247797 /// XM_005247799 /// XM_006713759 /// XM_006713760 /// XM_006713761 /// XM_006713762 /// XM_006713763 /// XM_006713764 /// XM_006713765 /// XM_006713766 0000077 // DNA damage checkpoint // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0042770 // signal transduction in response to DNA damage // inferred from sequence or structural similarity /// 0051225 // spindle assembly // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 222152_at AK024175 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024175.1 /DEF=Homo sapiens cDNA FLJ14113 fis, clone MAMMA1001715. /FEA=mRNA /DB_XREF=gi:10436491 /UG=Hs.323409 Homo sapiens cDNA FLJ14113 fis, clone MAMMA1001715 AK024175 programmed cell death 6 PDCD6 10016 NM_001267556 /// NM_001267557 /// NM_001267558 /// NM_001267559 /// NM_013232 /// NR_073609 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032007 // negative regulation of TOR signaling // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0036324 // vascular endothelial growth factor receptor-2 signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from mutant phenotype 222153_at AK023133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023133.1 /DEF=Homo sapiens cDNA FLJ13071 fis, clone NT2RP3001792, moderately similar to HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M. /FEA=mRNA /DB_XREF=gi:10434914 /UG=Hs.44268 myelin gene expression factor 2 AK023133 myelin expression factor 2 MYEF2 50804 NM_016132 /// XM_005254422 /// XM_005254423 /// XM_005254424 /// XM_005254425 /// XM_005254427 /// XM_006720553 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007518 // myoblast fate determination // traceable author statement /// 0014902 // myotube differentiation // inferred from expression pattern /// 0030182 // neuron differentiation // inferred from expression pattern /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222154_s_at AK002064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK002064.1 /DEF=Homo sapiens cDNA FLJ11202 fis, clone PLACE1007746. /FEA=mRNA /DB_XREF=gi:7023720 /UG=Hs.5297 DKFZP564A2416 protein AK002064 spermatogenesis associated, serine-rich 2-like SPATS2L 26010 NM_001100422 /// NM_001100423 /// NM_001100424 /// NM_001282735 /// NM_001282743 /// NM_001282744 /// NM_015535 /// XM_005246454 /// XM_005246456 /// XM_005246457 /// XM_005246458 /// XM_005246459 /// XM_005246460 /// XM_006712409 /// XM_006712410 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222155_s_at AK021918 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021918.1 /DEF=Homo sapiens cDNA FLJ11856 fis, clone HEMBA1006789. /FEA=mRNA /DB_XREF=gi:10433214 /UG=Hs.6459 hypothetical protein FLJ11856 AK021918 solute carrier family 52 (riboflavin transporter), member 2 SLC52A2 79581 NM_001253815 /// NM_001253816 /// NM_024531 /// NR_045600 /// XM_006716658 /// XM_006716659 /// XM_006716660 0006810 // transport // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0032218 // riboflavin transport // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001618 // virus receptor activity // inferred from electronic annotation /// 0032217 // riboflavin transporter activity // inferred from direct assay 222156_x_at AK022459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022459.1 /DEF=Homo sapiens cDNA FLJ12397 fis, clone MAMMA1002769, weakly similar to Homo sapiens cell cycle progression restoration 8 protein (CPR8) mRNA. /FEA=mRNA /DB_XREF=gi:10433861 /UG=Hs.82506 KIAA1254 protein AK022459 cell cycle progression 1 /// DYX1C1-CCPG1 readthrough (NMD candidate) CCPG1 /// DYX1C1-CCPG1 9236 /// 100533483 NM_001204450 /// NM_001204451 /// NM_004748 /// NM_020739 /// NR_037923 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001106 // regulation of Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 222157_s_at AB040882 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB040882.1 /DEF=Homo sapiens mRNA for KIAA1449 protein, partial cds. /FEA=mRNA /GEN=KIAA1449 /PROD=KIAA1449 protein /DB_XREF=gi:7959156 /UG=Hs.109778 KIAA1449 protein AB040882 WD repeat domain 48 WDR48 57599 NM_020839 /// XM_005265346 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222158_s_at AF229834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF229834.1 /DEF=Homo sapiens apoptosis-related protein PNAS-4 (PNAS-4) mRNA, partial cds. /FEA=mRNA /GEN=PNAS-4 /PROD=apoptosis-related protein PNAS-4 /DB_XREF=gi:7229639 /UG=Hs.42409 CGI-146 protein AF229834 desumoylating isopeptidase 2 DESI2 51029 NM_016076 /// XM_005273154 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 222159_at AK023058 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023058.1 /DEF=Homo sapiens cDNA FLJ12996 fis, clone NT2RP3000235. /FEA=mRNA /DB_XREF=gi:10434801 /UG=Hs.287546 Homo sapiens cDNA FLJ12996 fis, clone NT2RP3000235 AK023058 222160_at AL133576 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133576.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L0650 (from clone DKFZp434L0650); partial cds. /FEA=mRNA /GEN=DKFZp434L0650 /PROD=hypothetical protein /DB_XREF=gi:6599156 /UG=Hs.105549 Homo sapiens mRNA; cDNA DKFZp434L0650 (from clone DKFZp434L0650); partial cds AL133576 A kinase (PRKA) anchor protein 8-like AKAP8L 26993 NM_001291478 /// NM_014371 /// NR_111971 /// XM_005259854 /// XR_244065 /// XR_244066 /// XR_430135 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0017151 // DEAD/H-box RNA helicase binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222161_at AJ012370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ012370.1 /DEF=Homo sapiens mRNA for NAALADase II protein. /FEA=mRNA /GEN=naaladase II /PROD=NAALADase II protein /DB_XREF=gi:4539524 /UG=Hs.199292 N-acetylated alpha-linked acidic dipeptidase 2 AJ012370 N-acetylated alpha-linked acidic dipeptidase 2 NAALAD2 10003 NM_005467 /// XM_005273701 /// XM_005273702 /// XM_006718757 0006508 // proteolysis // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050129 // N-formylglutamate deformylase activity // inferred from electronic annotation 222162_s_at AK023795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023795.1 /DEF=Homo sapiens cDNA FLJ13733 fis, clone PLACE3000147, highly similar to Homo sapiens metalloproteinase with thrombospondin type 1 motifs ADAMTS1 (ADAMTS1) mRNA. /FEA=mRNA /DB_XREF=gi:10435838 /UG=Hs.8230 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 AK023795 ADAM metallopeptidase with thrombospondin type 1 motif, 1 ADAMTS1 9510 NM_006988 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0060347 // heart trabecula formation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222163_s_at BE890973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE890973 /FEA=EST /DB_XREF=gi:10349835 /DB_XREF=est:601431962F1 /CLONE=IMAGE:3917319 /UG=Hs.5555 hypothetical protein MGC5347 BE890973 spermatogenesis associated 5-like 1 SPATA5L1 79029 NM_024063 /// NR_027635 /// XM_005254657 /// XR_243126 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0070842 // aggresome assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from electronic annotation 222164_at AU145411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145411 /FEA=EST /DB_XREF=gi:11006932 /DB_XREF=est:AU145411 /CLONE=HEMBA1004753 /UG=Hs.274546 Homo sapiens cDNA FLJ10190 fis, clone HEMBA1004753 AU145411 fibroblast growth factor receptor 1 FGFR1 2260 NM_001174063 /// NM_001174064 /// NM_001174065 /// NM_001174066 /// NM_001174067 /// NM_015850 /// NM_023105 /// NM_023106 /// NM_023107 /// NM_023108 /// NM_023109 /// NM_023110 /// NM_023111 /// NM_032191 /// XM_006716303 /// XM_006716304 /// XM_006716305 /// XM_006716306 /// XM_006716307 /// XM_006716308 /// XM_006716309 /// XM_006716310 /// XM_006716311 /// XM_006716312 /// XM_006716313 /// XM_006716314 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001759 // organ induction // inferred from electronic annotation /// 0001764 // neuron migration // traceable author statement /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010518 // positive regulation of phospholipase activity // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from electronic annotation /// 0021847 // ventricular zone neuroblast division // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042473 // outer ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0043009 // chordate embryonic development // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045595 // regulation of cell differentiation // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048378 // regulation of lateral mesodermal cell fate specification // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048762 // mesenchymal cell differentiation // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060117 // auditory receptor cell development // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060484 // lung-associated mesenchyme development // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 222165_x_at AK022885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022885.1 /DEF=Homo sapiens cDNA FLJ12823 fis, clone NT2RP2002752. /FEA=mRNA /DB_XREF=gi:10434538 /UG=Hs.95867 hypothetical protein EST00098 AK022885 chromosome 9 open reading frame 16 C9orf16 79095 NM_024112 222166_at AK022885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022885.1 /DEF=Homo sapiens cDNA FLJ12823 fis, clone NT2RP2002752. /FEA=mRNA /DB_XREF=gi:10434538 /UG=Hs.95867 hypothetical protein EST00098 AK022885 chromosome 9 open reading frame 16 C9orf16 79095 NM_024112 222167_at AK021836 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021836.1 /DEF=Homo sapiens cDNA FLJ11774 fis, clone HEMBA1005884. /FEA=mRNA /DB_XREF=gi:10433104 /UG=Hs.293917 Homo sapiens cDNA FLJ11774 fis, clone HEMBA1005884 AK021836 222168_at AF198444 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF198444.1 /DEF=Homo sapiens 10q21 mRNA sequence. /FEA=mRNA /DB_XREF=gi:7025338 /UG=Hs.279024 Homo sapiens 10q21 mRNA sequence AF198444 Homo sapiens 10q21 mRNA sequence. AF198444 222169_x_at N71739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N71739 /FEA=EST /DB_XREF=gi:1228451 /DB_XREF=est:yw52h11.r1 /CLONE=IMAGE:255909 /UG=Hs.237554 Homo sapiens cDNA FLJ14306 fis, clone PLACE3000124 N71739 SH2 domain containing 3A SH2D3A 10045 NM_005490 /// XM_005259467 /// XM_005259472 /// XM_005259474 /// XM_006722602 0007254 // JNK cascade // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 222170_at AF098968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF098968.1 /DEF=Homo sapiens familial Mediterranean fever locus region, mRNA sequence. /FEA=mRNA /DB_XREF=gi:4323318 /UG=Hs.113111 Homo sapiens familial Mediterranean fever locus region, mRNA sequence AF098968 ZNF213 antisense RNA 1 (head to head) ZNF213-AS1 100507458 NR_110900 /// XR_243341 /// XR_248273 /// XR_253486 222171_s_at AK023792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023792.1 /DEF=Homo sapiens cDNA FLJ13730 fis, clone PLACE3000136. /FEA=mRNA /DB_XREF=gi:10435834 /UG=Hs.10043 hypothetical protein FLJ13074 AK023792 PBX/knotted 1 homeobox 2 PKNOX2 63876 NM_022062 /// XM_005271642 /// XM_005271643 /// XM_006718894 /// XM_006718895 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 222172_at AL079281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL079281.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 809726. /FEA=mRNA /PROD=hypothetical protein, similar to (U77968)neuronal PAS domain protein 1 Homo sapiens /DB_XREF=gi:5102587 /UG=Hs.190125 basic-helix-loop-helix-PAS protein AL079281 neuronal PAS domain protein 3 NPAS3 64067 NM_001164749 /// NM_001165893 /// NM_022123 /// NM_173159 /// XM_005267991 /// XM_005267992 /// XM_005267993 0001964 // startle response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 222173_s_at AK026105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026105.1 /DEF=Homo sapiens cDNA: FLJ22452 fis, clone HRC09667. /FEA=mRNA /DB_XREF=gi:10438847 /UG=Hs.135917 hypothetical protein DKFZp761D1823 AK026105 TBC1 domain family, member 2 TBC1D2 55357 NM_001267571 /// NM_001267572 /// NM_018421 /// NR_051978 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from physical interaction 222174_at AU145025 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU145025 /FEA=EST /DB_XREF=gi:11006546 /DB_XREF=est:AU145025 /CLONE=HEMBA1003667 /UG=Hs.296748 Homo sapiens cDNA FLJ14025 fis, clone HEMBA1003667 AU145025 222175_s_at AK000003 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000003.1 /DEF=Homo sapiens mRNA for FLJ00003 protein, partial cds. /FEA=mRNA /GEN=FLJ00003 /PROD=FLJ00003 protein /DB_XREF=gi:7209306 /UG=Hs.8657 TIG-1 AK000003 mediator complex subunit 15 MED15 51586 NM_001003891 /// NM_001293234 /// NM_001293235 /// NM_001293236 /// NM_001293237 /// NM_015889 /// XM_005261632 /// XM_006724261 /// XM_006724262 /// XM_006724263 /// XM_006724264 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222176_at AK021487 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021487.1 /DEF=Homo sapiens cDNA FLJ11425 fis, clone HEMBA1001051. /FEA=mRNA /DB_XREF=gi:10432680 /UG=Hs.306597 Homo sapiens cDNA FLJ11425 fis, clone HEMBA1001051 AK021487 222177_s_at AF244812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF244812 /DEF=Homo sapiens SCAN domain-containing protein 2 (SCAND2) gene, complete cds, alternatively spliced /FEA=mRNA_4 /DB_XREF=gi:11345047 /UG=Hs.283825 SCAN domain-containing 2 AF244812 SCAN domain containing 2 pseudogene SCAND2P 54581 NM_022050 /// NM_033633 /// NM_033634 /// NM_033635 /// NM_033636 /// NM_033640 /// NR_003654 /// NR_004859 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 222178_s_at AL133262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133262 /DEF=Human DNA sequence from clone RP1-319D22 on chromosome 6 Contains part of the gene for a CDC5-like protein, the gene for a novel protein (PRO0214), ESTs, an STS and GSSs /FEA=mRNA_1 /DB_XREF=gi:9366879 /UG=Hs.278932 PRO0214 protein AL133262 222179_at AL133262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133262 /DEF=Human DNA sequence from clone RP1-319D22 on chromosome 6 Contains part of the gene for a CDC5-like protein, the gene for a novel protein (PRO0214), ESTs, an STS and GSSs /FEA=mRNA_1 /DB_XREF=gi:9366879 /UG=Hs.278932 PRO0214 protein AL133262 cell division cycle 5-like CDC5L 988 NM_001253 /// XM_006715289 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071987 // WD40-repeat domain binding // inferred from direct assay 222180_at AU147889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147889 /FEA=EST /DB_XREF=gi:11009410 /DB_XREF=est:AU147889 /CLONE=MAMMA1002033 /UG=Hs.225729 Homo sapiens cDNA FLJ14122 fis, clone MAMMA1002033 AU147889 RP11-769O8.3 222181_at BG105204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG105204 /FEA=EST /DB_XREF=gi:12599050 /DB_XREF=est:602312951F1 /CLONE=IMAGE:4422541 /UG=Hs.239720 CCR4-NOT transcription complex, subunit 2 BG105204 CCR4-NOT transcription complex, subunit 2 CNOT2 4848 NM_001199302 /// NM_001199303 /// NM_014515 /// NR_037615 /// XM_006719429 /// XM_006719430 /// XM_006719431 /// XM_006719432 /// XM_006719433 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // traceable author statement /// 0001226 // RNA polymerase II transcription corepressor binding // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 222182_s_at BG105204 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG105204 /FEA=EST /DB_XREF=gi:12599050 /DB_XREF=est:602312951F1 /CLONE=IMAGE:4422541 /UG=Hs.239720 CCR4-NOT transcription complex, subunit 2 BG105204 CCR4-NOT transcription complex, subunit 2 CNOT2 4848 NM_001199302 /// NM_001199303 /// NM_014515 /// NR_037615 /// XM_006719429 /// XM_006719430 /// XM_006719431 /// XM_006719432 /// XM_006719433 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // traceable author statement /// 0001226 // RNA polymerase II transcription corepressor binding // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 222183_x_at AL390153 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390153.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762G113 (from clone DKFZp762G113). /FEA=mRNA /DB_XREF=gi:9368841 /UG=Hs.208339 Homo sapiens mRNA; cDNA DKFZp762G113 (from clone DKFZp762G113) AL390153 methyl-CpG binding domain protein 3 MBD3 53615 NM_001281453 /// NM_001281454 /// NM_003926 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048385 // regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0070564 // positive regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016581 // NuRD complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071146 // SMAD3-SMAD4 protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005112 // Notch binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay 222184_at AF131844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131844.1 /DEF=Homo sapiens clone 25015 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406685 /UG=Hs.201626 Homo sapiens clone 25015 mRNA sequence AF131844 long intergenic non-protein coding RNA 965 LINC00965 349196 NM_001025473 /// NR_027000 222185_at AK023792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023792.1 /DEF=Homo sapiens cDNA FLJ13730 fis, clone PLACE3000136. /FEA=mRNA /DB_XREF=gi:10435834 /UG=Hs.10043 hypothetical protein FLJ13074 AK023792 PBX/knotted 1 homeobox 2 PKNOX2 63876 NM_022062 /// XM_005271642 /// XM_005271643 /// XM_006718894 /// XM_006718895 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 222186_at AL109684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL109684.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 27080. /FEA=mRNA /DB_XREF=gi:5689805 /UG=Hs.306329 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 27080 AL109684 222187_x_at X78262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X78262.1 /DEF=H.sapiens mRNA for TRE5. /FEA=mRNA /DB_XREF=gi:587440 /UG=Hs.302178 H.sapiens mRNA for TRE5 X78262 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 /// XM_006714749 /// XM_006714750 0006200 // ATP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222188_at AK023069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023069.1 /DEF=Homo sapiens cDNA FLJ13007 fis, clone NT2RP3000451. /FEA=mRNA /DB_XREF=gi:10434818 /UG=Hs.9196 hypothetical protein AK023069 chromosome 9 open reading frame 156 C9orf156 51531 NM_016481 /// XM_005252047 /// XM_005252048 /// XM_005252049 /// XM_005252050 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 222189_at AB051523 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051523.1 /DEF=Homo sapiens mRNA for KIAA1736 protein, partial cds. /FEA=mRNA /GEN=KIAA1736 /PROD=KIAA1736 protein /DB_XREF=gi:12698016 /UG=Hs.7995 hypothetical protein FLJ20294 AB051523 222190_s_at BC000822 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC000822.1 /DEF=Homo sapiens, Similar to hypothetical protein FLJ13868, clone IMAGE:3454077, mRNA, partial cds. /FEA=mRNA /PROD=Similar to hypothetical protein FLJ13868 /DB_XREF=gi:12654036 /UG=Hs.9003 hypothetical protein FLJ13868 BC000822 chromosome 16 open reading frame 58 C16orf58 64755 NM_022744 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222191_s_at AK022566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022566.1 /DEF=Homo sapiens cDNA FLJ12504 fis, clone NT2RM2001698, highly similar to Homo sapiens XGalT-1 mRNA for galactosyltransferase I. /FEA=mRNA /DB_XREF=gi:10434029 /UG=Hs.54702 xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) AK022566 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 B4GALT7 11285 NM_007255 /// XM_005265805 /// XM_006714815 /// XM_006714816 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0008378 // galactosyltransferase activity // inferred from direct assay /// 0008378 // galactosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046525 // xylosylprotein 4-beta-galactosyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222192_s_at AK021672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021672.1 /DEF=Homo sapiens cDNA FLJ11610 fis, clone HEMBA1003985. /FEA=mRNA /DB_XREF=gi:10432904 /UG=Hs.63300 hypothetical protein FLJ21820 AK021672 chromosome 2 open reading frame 43 C2orf43 60526 NM_001282719 /// NM_001282720 /// NM_001282721 /// NM_001282722 /// NM_001282723 /// NM_001282724 /// NM_021925 /// NR_104233 /// XR_426990 /// XR_426991 /// XR_426992 222193_at AK021672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021672.1 /DEF=Homo sapiens cDNA FLJ11610 fis, clone HEMBA1003985. /FEA=mRNA /DB_XREF=gi:10432904 /UG=Hs.63300 hypothetical protein FLJ21820 AK021672 chromosome 2 open reading frame 43 C2orf43 60526 NM_001282719 /// NM_001282720 /// NM_001282721 /// NM_001282722 /// NM_001282723 /// NM_001282724 /// NM_021925 /// NR_104233 /// XR_426990 /// XR_426991 /// XR_426992 222194_at AL390183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL390183.1 /DEF=Homo sapiens mRNA; cDNA DKFZp547D096 (from clone DKFZp547D096). /FEA=mRNA /DB_XREF=gi:9368895 /UG=Hs.88121 Homo sapiens mRNA; cDNA DKFZp547D096 (from clone DKFZp547D096) AL390183 family with sequence similarity 66, member D FAM66D 100132923 NR_027425 /// XR_426507 222195_s_at AK023069 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023069.1 /DEF=Homo sapiens cDNA FLJ13007 fis, clone NT2RP3000451. /FEA=mRNA /DB_XREF=gi:10434818 /UG=Hs.9196 hypothetical protein AK023069 chromosome 9 open reading frame 156 C9orf156 51531 NM_016481 /// XM_005252047 /// XM_005252048 /// XM_005252049 /// XM_005252050 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 222196_at AK000470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000470.1 /DEF=Homo sapiens cDNA FLJ20463 fis, clone KAT06143. /FEA=mRNA /DB_XREF=gi:7020580 /UG=Hs.120769 Homo sapiens cDNA FLJ20463 fis, clone KAT06143 AK000470 zinc finger protein 839 pseudogene LOC389906 389906 NR_034031 222197_s_at AF131813 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF131813.1 /DEF=Homo sapiens clone 24970 mRNA sequence. /FEA=mRNA /DB_XREF=gi:4406647 /UG=Hs.21258 Homo sapiens cDNA FLJ13094 fis, clone NT2RP3002163 AF131813 0001947 // heart looping // inferred from mutant phenotype /// 0003341 // cilium movement // inferred from genetic interaction /// 0030030 // cell projection organization // inferred from electronic annotation /// 0036158 // outer dynein arm assembly // inferred from genetic interaction /// 0036159 // inner dynein arm assembly // inferred from genetic interaction /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred by curator /// 0070286 // axonemal dynein complex assembly // inferred from mutant phenotype /// 0071907 // determination of digestive tract left/right asymmetry // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0042803 // protein homodimerization activity // inferred from direct assay 222198_at AA447740 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA447740 /FEA=EST /DB_XREF=gi:2161410 /DB_XREF=est:aa18f05.s1 /CLONE=IMAGE:813633 /UG=Hs.99139 Homo sapiens cDNA: FLJ22948 fis, clone KAT09449 AA447740 RP11-930P14.2 222199_s_at AK001289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001289.1 /DEF=Homo sapiens cDNA FLJ10427 fis, clone NT2RP1000348, weakly similar to REDUCED VIABILITY UPON STARVATION PROTEIN 161. /FEA=mRNA /DB_XREF=gi:7022450 /UG=Hs.68090 bridging integrator-3 AK001289 bridging integrator 3 BIN3 55909 NM_018688 /// XM_005273573 0000910 // cytokinesis // non-traceable author statement /// 0000917 // barrier septum assembly // inferred from electronic annotation /// 0007015 // actin filament organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0009826 // unidimensional cell growth // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement 222200_s_at AK021440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK021440.1 /DEF=Homo sapiens cDNA FLJ11378 fis, clone HEMBA1000456. /FEA=mRNA /DB_XREF=gi:10432625 /UG=Hs.6937 hypothetical protein FLJ10276 AK021440 BSD domain containing 1 BSDC1 55108 NM_001143888 /// NM_001143889 /// NM_001143890 /// NM_018045 /// XM_005270985 /// XM_005270986 222201_s_at AB037736 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB037736.1 /DEF=Homo sapiens mRNA for KIAA1315 protein, partial cds. /FEA=mRNA /GEN=KIAA1315 /PROD=KIAA1315 protein /DB_XREF=gi:7243010 /UG=Hs.122843 CASP8 associated protein 2 AB037736 caspase 8 associated protein 2 CASP8AP2 9994 NM_001137667 /// NM_001137668 /// NM_012115 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from sequence or structural similarity /// 0036337 // Fas signaling pathway // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from sequence or structural similarity /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from sequence or structural similarity /// 0032184 // SUMO polymer binding // inferred from direct assay 222202_at AK024355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024355.1 /DEF=Homo sapiens cDNA FLJ14293 fis, clone PLACE1007866. /FEA=mRNA /DB_XREF=gi:10436719 /UG=Hs.141009 Homo sapiens cDNA FLJ14293 fis, clone PLACE1007866 AK024355 222203_s_at AK023625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023625.1 /DEF=Homo sapiens cDNA FLJ13563 fis, clone PLACE1008111, weakly similar to PROBABLE OXIDOREDUCTASE (EC 1.-.-.-). /FEA=mRNA /DB_XREF=gi:10435607 /UG=Hs.288880 PAN2 protein AK023625 NT5C1B-RDH14 readthrough /// retinol dehydrogenase 14 (all-trans/9-cis/11-cis) NT5C1B-RDH14 /// RDH14 57665 /// 100526794 NM_001199103 /// NM_001199104 /// NM_020905 0001649 // osteoblast differentiation // inferred from direct assay /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 222204_s_at AL110238 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL110238.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566E104 (from clone DKFZp566E104); partial cds. /FEA=mRNA /GEN=DKFZp566E104 /PROD=hypothetical protein /DB_XREF=gi:5817180 /UG=Hs.189834 DKFZP566E104 protein AL110238 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) RRN3 54700 NM_018427 /// XM_005255375 /// XM_005255376 /// XM_005255377 /// XM_006725197 /// XM_006725198 /// XM_006725199 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 1902254 // negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 2000142 // regulation of DNA-templated transcription, initiation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0070063 // RNA polymerase binding // inferred from electronic annotation 222205_x_at AA446466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA446466 /FEA=EST /DB_XREF=gi:2159131 /DB_XREF=est:zw65b12.s1 /CLONE=IMAGE:781055 /UG=Hs.193783 Human DNA sequence from clone RP13-329D4 on chromosome 20 Contains ESTs, STSs, GSSs and a CpG island. Contains the 3 part of a novel gene, a gene similar to NCOR1 for a truncated form of nuclear receptor co-repressor 1 (retinoid X receptor interacting pr AA446466 family with sequence similarity 182, member B /// family with sequence similarity 27, member B /// family with sequence similarity 27, member C FAM182B /// FAM27B /// FAM27C 728882 /// 100132948 /// 100133121 NM_001024942 /// NR_024060 /// NR_026714 /// NR_027061 /// NR_027421 /// NR_027422 222206_s_at AA781143 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA781143 /FEA=EST /DB_XREF=gi:2840474 /DB_XREF=est:aj24a08.s1 /CLONE=1391222 /UG=Hs.24983 hypothetical protein from EUROIMAGE 2021883 AA781143 nicalin NCLN 56926 NM_020170 /// XM_005259596 0006508 // proteolysis // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation 222207_x_at AK024602 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024602.1 /DEF=Homo sapiens cDNA: FLJ20949 fis, clone ADSE01902. /FEA=mRNA /DB_XREF=gi:10436915 /UG=Hs.220255 Homo sapiens cDNA: FLJ20949 fis, clone ADSE01902 AK024602 222208_s_at W07700 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W07700 /FEA=EST /DB_XREF=gi:1281742 /DB_XREF=est:zb03a07.r1 /CLONE=IMAGE:300948 /UG=Hs.220255 Homo sapiens cDNA: FLJ20949 fis, clone ADSE01902 W07700 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene POLR2J4 84820 NM_032734 /// NR_003655 222209_s_at AK000684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000684.1 /DEF=Homo sapiens cDNA FLJ20677 fis, clone KAIA4183. /FEA=mRNA /DB_XREF=gi:7020930 /UG=Hs.183887 hypothetical protein FLJ22104 AK000684 transmembrane protein 135 TMEM135 65084 NM_001168724 /// NM_022918 /// NR_033149 /// XM_006718667 /// XM_006718668 0007031 // peroxisome organization // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222210_at AK025262 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025262.1 /DEF=Homo sapiens cDNA: FLJ21609 fis, clone COL07316. /FEA=mRNA /DB_XREF=gi:10437737 /UG=Hs.274408 KIAA1139 protein AK025262 KIAA0195 /// microRNA 6785 KIAA0195 /// MIR6785 9772 /// 102466911 NM_014738 /// NR_106843 /// XM_005257863 /// XM_005257864 /// XM_005257865 /// XM_005257866 /// XM_005257867 /// XM_005257868 /// XM_006722200 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222211_x_at AF244812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF244812 /DEF=Homo sapiens SCAN domain-containing protein 2 (SCAND2) gene, complete cds, alternatively spliced /FEA=mRNA_2 /DB_XREF=gi:11345047 /UG=Hs.283825 SCAN domain-containing 2 AF244812 SCAN domain containing 2 pseudogene SCAND2P 54581 NM_022050 /// NM_033633 /// NM_033634 /// NM_033635 /// NM_033636 /// NM_033640 /// NR_003654 /// NR_004859 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 222212_s_at AK001105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001105.1 /DEF=Homo sapiens cDNA FLJ10243 fis, clone HEMBB1000631, weakly similar to LONGEVITY-ASSURANCE PROTEIN 1. /FEA=mRNA /DB_XREF=gi:7022160 /UG=Hs.285976 tumor metastasis-suppressor AK001105 ceramide synthase 2 CERS2 29956 NM_013384 /// NM_022075 /// NM_181746 /// XM_005245107 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0050291 // sphingosine N-acyltransferase activity // inferred from electronic annotation 222213_x_at AU147800 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AU147800 /FEA=EST /DB_XREF=gi:11009321 /DB_XREF=est:AU147800 /CLONE=MAMMA1001745 /UG=Hs.296710 Homo sapiens cDNA FLJ12281 fis, clone MAMMA1001745 AU147800 222214_at AK024988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK024988.1 /DEF=Homo sapiens cDNA: FLJ21335 fis, clone COL02546. /FEA=mRNA /DB_XREF=gi:10437419 /UG=Hs.303001 Homo sapiens cDNA: FLJ21335 fis, clone COL02546 AK024988 222215_at AK022786 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022786.1 /DEF=Homo sapiens cDNA FLJ12724 fis, clone NT2RP1001385, weakly similar to HYPOTHETICAL 48.8 KD PROTEIN IN SSU81-SCS2 INTERGENIC REGION. /FEA=mRNA /DB_XREF=gi:10434390 /UG=Hs.10499 hypothetical protein FLJ10815 AK022786 solute carrier family 38, member 7 SLC38A7 55238 NM_018231 /// XM_006721229 /// XR_429722 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from electronic annotation /// 0006867 // asparagine transport // inferred from electronic annotation /// 0006868 // glutamine transport // inferred from electronic annotation /// 0015803 // branched-chain amino acid transport // inferred from electronic annotation /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0015808 // L-alanine transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015817 // histidine transport // inferred from electronic annotation /// 0015821 // methionine transport // inferred from electronic annotation /// 0015825 // L-serine transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005290 // L-histidine transmembrane transporter activity // inferred from electronic annotation /// 0005313 // L-glutamate transmembrane transporter activity // inferred from electronic annotation /// 0015179 // L-amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015180 // L-alanine transmembrane transporter activity // inferred from electronic annotation /// 0015182 // L-asparagine transmembrane transporter activity // inferred from electronic annotation /// 0015183 // L-aspartate transmembrane transporter activity // inferred from electronic annotation /// 0015186 // L-glutamine transmembrane transporter activity // inferred from sequence or structural similarity /// 0015190 // L-leucine transmembrane transporter activity // inferred from electronic annotation /// 0015191 // L-methionine transmembrane transporter activity // inferred from electronic annotation /// 0015194 // L-serine transmembrane transporter activity // inferred from electronic annotation 222216_s_at AK026857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026857.1 /DEF=Homo sapiens cDNA: FLJ23204 fis, clone ADSE00191. /FEA=mRNA /DB_XREF=gi:10439813 /UG=Hs.10026 ribosomal protein L17 isolog AK026857 mitochondrial ribosomal protein L17 MRPL17 63875 NM_022061 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction 222217_s_at BC003654 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BC003654.1 /DEF=Homo sapiens, Similar to hypothetical protein MGC4365, clone IMAGE:3538020, mRNA, partial cds. /FEA=mRNA /PROD=Similar to hypothetical protein MGC4365 /DB_XREF=gi:13177768 /UG=Hs.109274 hypothetical protein MGC4365 BC003654 solute carrier family 27 (fatty acid transporter), member 3 SLC27A3 11000 NM_024330 /// XM_005244852 /// XM_005276734 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004321 // fatty-acyl-CoA synthase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 222218_s_at AJ400843 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ400843.1 /DEF=Homo sapiens partial mRNA for immunoglobulin-like cell surface receptor FDF03-M14, soluble alternative form. /FEA=mRNA /GEN=FDF03-M14 /PROD=cell surface receptor FDF03-M14 /DB_XREF=gi:9715838 /UG=Hs.122591 paired immunoglobulin-like receptor alpha AJ400843 paired immunoglobin-like type 2 receptor alpha PILRA 29992 NM_013439 /// NM_178272 /// NM_178273 /// XM_006715954 /// XM_006715955 0007165 // signal transduction // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222219_s_at AC007766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC007766 /DEF=Homo sapiens chromosome 19, cosmid R26610 /FEA=CDS_2 /DB_XREF=gi:5030437 /UG=Hs.128417 hypothetical protein FLJ14009 AC007766 transducin-like enhancer of split 6 TLE6 79816 NM_001143986 /// NM_024760 /// XM_005259645 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 222220_s_at AK027245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK027245.1 /DEF=Homo sapiens cDNA: FLJ23592 fis, clone LNG14731, highly similar to AF132730 Homo sapiens unknown mRNA. /FEA=mRNA /DB_XREF=gi:10440332 /UG=Hs.149784 hypothetical protein AK027245 translin-associated factor X interacting protein 1 TSNAXIP1 55815 NM_001288990 /// NM_001288991 /// NM_001288992 /// NM_001288993 /// NM_001288994 /// NM_018430 /// XM_005256049 /// XM_005256051 /// XM_005256052 /// XM_005256053 /// XM_005256054 /// XM_006721234 /// XM_006721235 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 222221_x_at AY007161 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AY007161.1 /DEF=Homo sapiens clone CDABP0131 mRNA sequence. /FEA=mRNA /DB_XREF=gi:9956075 /UG=Hs.155119 EH domain containing 1 AY007161 EH-domain containing 1 EHD1 10938 NM_001282444 /// NM_001282445 /// NM_006795 /// XM_006718424 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010886 // positive regulation of cholesterol storage // inferred from sequence or structural similarity /// 0016197 // endosomal transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from physical interaction /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 222222_s_at AC002985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC002985 /DEF=Human DNA from chromosome 19-specific cosmid R27090, genomic sequence /FEA=CDS_1 /DB_XREF=gi:2443868 /UG=Hs.166146 Homer, neuronal immediate early gene, 3 AC002985 homer homolog 3 (Drosophila) HOMER3 9454 NM_001145721 /// NM_001145722 /// NM_001145724 /// NM_004838 /// NR_027297 /// XM_006722943 /// XM_006722944 0006605 // protein targeting // traceable author statement /// 0007216 // G-protein coupled glutamate receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 222223_s_at AF216693 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF216693 /DEF=Homo sapiens interleukin-1 receptor antagonist homolog 1 (IL1HY1) gene, complete cds /FEA=mRNA_1 /DB_XREF=gi:8572054 /UG=Hs.207224 interleukin-1 receptor antagonist homolog 1 AF216693 interleukin 36 receptor antagonist IL36RN 26525 NM_012275 /// NM_173170 /// XM_005263638 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0001960 // negative regulation of cytokine-mediated signaling pathway // traceable author statement /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005152 // interleukin-1 receptor antagonist activity // inferred from electronic annotation 222224_at AJ278883 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AJ278883 /DEF=Homo sapiens alpha-NAC gene for nascent polypeptide-associated complex component /FEA=CDS /DB_XREF=gi:9968299 /UG=Hs.287764 Homo sapiens alpha-NAC gene for nascent polypeptide-associated complex component AJ278883 nascent polypeptide-associated complex alpha subunit 2 NACA2 342538 NM_199290 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation 222225_at AC004908 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC004908 /DEF=Homo sapiens PAC clone RP5-855D21 /FEA=CDS_2 /DB_XREF=gi:4156179 /UG=Hs.247828 Homo sapiens, Similar to ribosomal protein L23a, clone MGC:2597, mRNA, complete cds AC004908 ribosomal protein L23a pseudogene 53 RPL23AP53 644128 NR_003572 222226_at X13895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:X13895 /DEF=Human serum amyloid A (GSAA1) gene, complete cds /FEA=CDS /DB_XREF=gi:36305 /UG=Hs.247968 Human serum amyloid A (GSAA1) gene, complete cds X13895 serum amyloid A3 pseudogene SAA3P 6290 NR_026576 222227_at AK000847 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000847.1 /DEF=Homo sapiens cDNA FLJ20840 fis, clone ADKA02336. /FEA=mRNA /DB_XREF=gi:7021168 /UG=Hs.283619 zinc finger protein 236 AK000847 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001956 // positive regulation of neurotransmitter secretion // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002695 // negative regulation of leukocyte activation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010579 // positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0019228 // neuronal action potential // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from sequence or structural similarity /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031959 // mineralocorticoid receptor signaling pathway // inferred from sequence or structural similarity /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051053 // negative regulation of DNA metabolic process // inferred from sequence or structural similarity /// 0051055 // negative regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070474 // positive regulation of uterine smooth muscle contraction // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from direct assay /// 0071389 // cellular response to mineralocorticoid stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0032591 // dendritic spine membrane // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from sequence or structural similarity /// 0043679 // axon terminus // inferred from sequence or structural similarity /// 0044327 // dendritic spine head // inferred from sequence or structural similarity /// 0045095 // keratin filament // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0017082 // mineralocorticoid receptor activity // inferred from sequence or structural similarity /// 0030284 // estrogen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 222228_s_at AK026097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026097.1 /DEF=Homo sapiens cDNA: FLJ22444 fis, clone HRC09425. /FEA=mRNA /DB_XREF=gi:10438836 /UG=Hs.272018 hypothetical protein FLJ20013 AK026097 alkB, alkylation repair homolog 4 (E. coli) ALKBH4 54784 NM_017621 /// XM_005250464 /// XM_005250465 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006482 // protein demethylation // inferred from direct assay /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0036090 // cleavage furrow ingression // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070938 // contractile ring // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from direct assay /// 0032451 // demethylase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 222229_x_at AL121871 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL121871 /DEF=Human DNA sequence from clone RP13-258O15 on chromosome Xq21.2-Xq21.33 Contains a pseudogene similar to ribosomal protein L26, STSs and GSSs /FEA=CDS /DB_XREF=gi:6855342 /UG=Hs.272344 Human DNA sequence from clone RP13-258O15 on chromosome Xq21.2-Xq21.33 Contains a pseudogene similar to ribosomal protein L26, STSs and GSSs AL121871 /// ribosomal protein L26 pseudogene 37 /// RP13-258O15.1 /// RPL26P37 /// RPL26P37 222230_s_at AK022248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022248.1 /DEF=Homo sapiens cDNA FLJ12186 fis, clone MAMMA1000824, weakly similar to ACTIN. /FEA=mRNA /DB_XREF=gi:10433604 /UG=Hs.274369 uncharacterized hypothalamus protein HARP11 AK022248 actin-related protein 10 homolog (S. cerevisiae) ACTR10 55860 NM_018477 0007018 // microtubule-based movement // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 222231_s_at AK025328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK025328.1 /DEF=Homo sapiens cDNA: FLJ21675 fis, clone COL09090, highly similar to AF119857 Homo sapiens PRO1855 mRNA. /FEA=mRNA /DB_XREF=gi:10437822 /UG=Hs.283558 hypothetical protein PRO1855 AK025328 leucine rich repeat containing 59 LRRC59 55379 NM_018509 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222233_s_at AK022922 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022922.1 /DEF=Homo sapiens cDNA FLJ12860 fis, clone NT2RP2003559. /FEA=mRNA /DB_XREF=gi:10434591 /UG=Hs.28891 hypothetical protein FLJ11360 AK022922 DNA cross-link repair 1C DCLRE1C 64421 NM_001033855 /// NM_001033857 /// NM_001033858 /// NM_001289076 /// NM_001289077 /// NM_001289078 /// NM_001289079 /// NM_022487 /// NR_110297 /// XM_005252558 /// XM_006717491 /// XR_242702 0000723 // telomere maintenance // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 222234_s_at AK022644 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK022644.1 /DEF=Homo sapiens cDNA FLJ12582 fis, clone NT2RM4001151. /FEA=mRNA /DB_XREF=gi:10434156 /UG=Hs.301394 hypothetical protein MGC3101 AK022644 dysbindin (dystrobrevin binding protein 1) domain containing 1 DBNDD1 79007 NM_001042610 /// NM_001288708 /// NM_001288709 /// NM_024043 0005737 // cytoplasm // inferred from electronic annotation 222235_s_at AL139812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL139812 /DEF=Human DNA sequence from clone RP1-19N1 on chromosome Xq21.33-22.3 Contains a gene for a novel protein. Contains ESTs, STSs and GSSs /FEA=mRNA /DB_XREF=gi:9187185 /UG=Hs.287761 Human DNA sequence from clone RP1-19N1 on chromosome Xq21.33-22.3 Contains a gene for a novel protein. Contains ESTs, STSs and GSSs AL139812 chondroitin sulfate N-acetylgalactosaminyltransferase 2 CSGALNACT2 55454 NM_018590 /// XM_005271819 /// XM_005271820 /// XM_005271821 0005975 // carbohydrate metabolic process // traceable author statement /// 0030166 // proteoglycan biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050652 // dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // traceable author statement /// 0050653 // chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008376 // acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047237 // glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation 222236_s_at AK000253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000253.1 /DEF=Homo sapiens cDNA FLJ20246 fis, clone COLF6458. /FEA=mRNA /DB_XREF=gi:7020209 /UG=Hs.44579 hypothetical protein FLJ20199 AK000253 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 ASAP3 55616 NM_001143778 /// NM_017707 /// XM_005245934 0016477 // cell migration // inferred from mutant phenotype /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0032850 // positive regulation of ARF GTPase activity // inferred from direct assay /// 0051492 // regulation of stress fiber assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222237_s_at AC084239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC084239 /DEF=Homo sapiens chromosome 19, BAC CTC-512J12 (BC347040), complete sequence /FEA=mRNA_2 /DB_XREF=gi:10864171 /UG=Hs.48589 zinc finger protein 228 AC084239 zinc finger protein 112 ZNF112 7771 NM_001083335 /// NM_013380 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222238_s_at AK023002 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023002.1 /DEF=Homo sapiens cDNA FLJ12940 fis, clone NT2RP2005038, weakly similar to DNA NUCLEOTIDYLEXOTRANSFERASE (EC 2.7.7.31). /FEA=mRNA /DB_XREF=gi:10434715 /UG=Hs.46964 polymerase (DNA-directed), mu AK023002 polymerase (DNA directed), mu POLM 27434 NM_001284330 /// NM_001284331 /// NM_013284 /// NR_104299 /// XM_005249708 /// XM_005249711 /// XM_006715692 /// XM_006715693 /// XM_006715694 /// XM_006715695 /// XM_006715696 /// XM_006715697 /// XM_006715698 /// XM_006715699 /// XM_006715700 /// XM_006715701 /// XR_242073 /// XR_242074 /// XR_428076 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222239_s_at AL117626 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117626.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B105 (from clone DKFZp434B105); partial cds. /FEA=mRNA /GEN=DKFZp434B105 /PROD=hypothetical protein /DB_XREF=gi:5912207 /UG=Hs.58570 deleted in cancer 1; RNA helicase HDBDICE1 AL117626 integrator complex subunit 6 INTS6 26512 NM_001039937 /// NM_001039938 /// NM_012141 /// XM_005266340 /// XM_005266341 0007165 // signal transduction // traceable author statement /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 222240_s_at AL137749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137749.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A0612 (from clone DKFZp434A0612); partial cds. /FEA=mRNA /GEN=DKFZp434A0612 /PROD=hypothetical protein /DB_XREF=gi:6808384 /UG=Hs.33713 myo-inositol 1-phosphate synthase A1 AL137749 inositol-3-phosphate synthase 1 ISYNA1 51477 NM_001170938 /// NM_001170939 /// NM_001253389 /// NM_016368 /// NR_045573 /// NR_045574 /// XM_006722766 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004512 // inositol-3-phosphate synthase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation 222241_at AK000001 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000001.1 /DEF=Homo sapiens mRNA for FLJ00001 protein, partial cds. /FEA=mRNA /GEN=FLJ00001 /PROD=FLJ00001 protein /DB_XREF=gi:7209302 /UG=Hs.4914 Homo sapiens mRNA for FLJ00031 protein, partial cds AK000001 multivesicular body subunit 12B MVB12B 89853 NM_001011703 /// NM_033446 /// XM_005252297 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from mutant phenotype /// 0043130 // ubiquitin binding // inferred from direct assay 222242_s_at AF243527 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF243527 /DEF=Homo sapiens serine protease gene cluster, complete sequence /FEA=CDS_12 /DB_XREF=gi:11244757 /UG=Hs.50915 kallikrein 5 AF243527 kallikrein-related peptidase 5 KLK5 25818 NM_001077491 /// NM_001077492 /// NM_012427 0006508 // proteolysis // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0097209 // epidermal lamellar body // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 222243_s_at AB051450 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051450.1 /DEF=Homo sapiens mRNA for KIAA1663 protein, partial cds. /FEA=mRNA /GEN=KIAA1663 /PROD=KIAA1663 protein /DB_XREF=gi:13359198 /UG=Hs.4994 transducer of ERBB2, 2 AB051450 transducer of ERBB2, 2 TOB2 10766 NM_016272 /// XM_005261315 /// XM_006724105 0007292 // female gamete generation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // inferred from electronic annotation 222244_s_at AK000749 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000749.1 /DEF=Homo sapiens cDNA FLJ20742 fis, clone HEP06891. /FEA=mRNA /DB_XREF=gi:7021031 /UG=Hs.52184 hypothetical protein FLJ20618 AK000749 taurine up-regulated 1 (non-protein coding) TUG1 55000 NR_002323 /// NR_110492 /// NR_110493 222245_s_at AF218012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF218012.1 /DEF=Homo sapiens clone PP3795 unknown mRNA. /FEA=mRNA /PROD=unknown /DB_XREF=gi:10441953 /UG=Hs.72222 hypothetical protein FLJ13459 AF218012 fer-1-like family member 4, pseudogene (functional) FER1L4 80307 NR_001442 /// NR_024377 /// NR_119376 /// XR_425236 /// XR_430316 /// XR_433611 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222246_at AF090913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF090913.1 /DEF=Homo sapiens clone HQ0290. /FEA=mRNA /DB_XREF=gi:6690199 /UG=Hs.76293 thymosin, beta 10 AF090913 222247_at S58722 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:S58722.1 /DEF=X-linked retinopathy protein {3 region, clone XEH.8c} human, mRNA Partial, 390 nt. /FEA=mRNA /GEN=X-linked retinopathy protein /DB_XREF=gi:299470 /UG=Hs.326552 putative X-linked retinopathy protein S58722 222248_s_at AC003982 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AC003982 /DEF=Homo sapiens PAC clone 166H1 from 12q /FEA=CDS_2 /DB_XREF=gi:2769695 /UG=Hs.50861 sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 4 AC003982 sirtuin 4 SIRT4 23409 NM_012240 /// XM_005253865 /// XM_006719308 /// XM_006719309 /// XM_006719310 /// XM_006719311 /// XM_006719312 0006342 // chromatin silencing // traceable author statement /// 0006471 // protein ADP-ribosylation // inferred from sequence or structural similarity /// 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0034983 // peptidyl-lysine deacetylation // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from mutant phenotype /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034979 // NAD-dependent protein deacetylase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 222249_at AB051438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB051438.1 /DEF=Homo sapiens mRNA for KIAA1651 protein, partial cds. /FEA=mRNA /GEN=KIAA1651 /PROD=KIAA1651 protein /DB_XREF=gi:13359174 /UG=Hs.34856 Homo sapiens mRNA for KIAA1651 protein, partial cds AB051438 222250_s_at AK001363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK001363.1 /DEF=Homo sapiens cDNA FLJ10501 fis, clone NT2RP2000412. /FEA=mRNA /DB_XREF=gi:7022575 /UG=Hs.48604 DKFZP434B168 protein AK001363 integrator complex subunit 7 INTS7 25896 NM_001199809 /// NM_001199811 /// NM_001199812 /// NM_015434 /// NR_037667 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016180 // snRNA processing // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222251_s_at AL133646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL133646.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F097 (from clone DKFZp434F097). /FEA=mRNA /GEN=DKFZp434F097 /PROD=hypothetical protein /DB_XREF=gi:6599185 /UG=Hs.28906 glucocorticoid modulatory element binding protein 2 AL133646 glucocorticoid modulatory element binding protein 2 GMEB2 26205 NM_012384 /// XM_005260202 /// XM_006723776 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222252_x_at AK023354 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK023354.1 /DEF=Homo sapiens cDNA FLJ13292 fis, clone OVARC1001180, weakly similar to UBIQUITIN-LIKE PROTEIN DSK2. /FEA=mRNA /DB_XREF=gi:10435253 /UG=Hs.283739 ataxin-1 ubiquitin-like interacting protein AK023354 ubiquilin 4 UBQLN4 56893 NM_020131 /// XM_005245347 /// XM_005245348 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0031595 // nuclear proteasome complex // inferred from direct assay /// 0031597 // cytosolic proteasome complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 222253_s_at AL117484 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL117484.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434H191 (from clone DKFZp434H191). /FEA=mRNA /DB_XREF=gi:5911964 /UG=Hs.278387 DKFZp434P211 protein AL117484 POM121 transmembrane nucleoporin-like 9, pseudogene POM121L9P 29774 NM_014549 /// NR_003714 222254_at AL034429 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL034429 /DEF=Human DNA sequence from clone RP5-894K16 on chromosome 20q113.11-13.13. Contains a COX6C (cytochrome c oxidase subunit VIc) pseudogene, STSs, GSSs and a predicted CpG island /FEA=CDS /DB_XREF=gi:4376012 /UG=Hs.274259 Human DNA sequence from clone RP5-894K16 on chromosome 20q113.11-13.13. Contains a COX6C (cytochrome c oxidase subunit VIc) pseudogene, STSs, GSSs and a predicted CpG island AL034429 cytochrome c oxidase subunit VIc pseudogene 2 /// COX6CP2 /// COX6CP2 222255_at AB046840 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AB046840.1 /DEF=Homo sapiens mRNA for KIAA1620 protein, partial cds. /FEA=mRNA /GEN=KIAA1620 /PROD=KIAA1620 protein /DB_XREF=gi:10047316 /UG=Hs.205457 periaxin AB046840 periaxin PRX 57716 NM_020956 /// NM_181882 /// XM_005259111 0008219 // cell death // inferred from electronic annotation /// 0008366 // axon ensheathment // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 222256_s_at AK000550 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK000550.1 /DEF=Homo sapiens cDNA FLJ20543 fis, clone KAT11396, highly similar to AF065215 Homo sapiens cytosolic phospholipase A2 beta. /FEA=mRNA /DB_XREF=gi:7020720 /UG=Hs.198161 phospholipase A2, group IVB (cytosolic) AK000550 jumonji domain containing 7 /// JMJD7-PLA2G4B readthrough JMJD7 /// JMJD7-PLA2G4B 8681 /// 100137047 NM_001114632 /// NM_001198588 /// NM_005090 /// NR_015346 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007567 // parturition // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046475 // glycerophospholipid catabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0004622 // lysophospholipase activity // non-traceable author statement /// 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from direct assay 222257_s_at AK026461 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026461.1 /DEF=Homo sapiens cDNA: FLJ22808 fis, clone KAIA2925. /FEA=mRNA /DB_XREF=gi:10439331 /UG=Hs.178098 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 AK026461 angiotensin I converting enzyme 2 ACE2 59272 NM_021804 0001817 // regulation of cytokine production // inferred by curator /// 0002003 // angiotensin maturation // traceable author statement /// 0002005 // angiotensin catabolic process in blood // inferred by curator /// 0003051 // angiotensin-mediated drinking behavior // inferred from mutant phenotype /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0032800 // receptor biosynthetic process // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042312 // regulation of vasodilation // inferred by curator /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046718 // viral entry into host cell // traceable author statement /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred by curator /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred by curator 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0001618 // virus receptor activity // inferred from mutant phenotype /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004180 // carboxypeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008241 // peptidyl-dipeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222258_s_at AF015043 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AF015043.1 /DEF=Homo sapiens EH-binding protein mRNA, partial cds. /FEA=mRNA /PROD=EH-binding protein /DB_XREF=gi:4102710 /UG=Hs.17667 SH3-domain binding protein 4 AF015043 SH3-domain binding protein 4 SH3BP4 23677 NM_014521 0006897 // endocytosis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0043090 // amino acid import // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from mutant phenotype /// 0061462 // protein localization to lysosome // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 222259_s_at AL135939 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL135939 /DEF=Human DNA sequence from clone RP3-481F12 on chromosome 20 Contains Spo11 (meiotic protein covalently bound to DSB (S. cerevisiae)-like), the 5 end of RAE1 (a mRNA export protein), a MTND1 (NADH dehydrogenase subunit 1) pseudogene, a Ribosomal L3... /FEA=mRNA_2 /DB_XREF=gi:8649107 /UG=Hs.159737 SPO11, meiotic protein covalently bound to DSB (S. cerevisiae)-like AL135939 SPO11 meiotic protein covalently bound to DSB SPO11 23626 NM_012444 /// NM_198265 /// XM_005260379 /// XM_005260380 /// XM_005260381 /// XM_005260382 /// XR_244137 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0034502 // protein localization to chromosome // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 222260_at AK026947 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AK026947.1 /DEF=Homo sapiens cDNA: FLJ23294 fis, clone HEP10564. /FEA=mRNA /DB_XREF=gi:10439927 /UG=Hs.154729 3-phosphoinositide dependent protein kinase-1 AK026947 CTD-3126B10.1 222261_at AL137316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137316.1 /DEF=Homo sapiens mRNA; cDNA DKFZp727K101 (from clone DKFZp727K101); partial cds. /FEA=mRNA /GEN=DKFZp727K101 /PROD=hypothetical protein /DB_XREF=gi:6807803 /UG=Hs.14449 KIAA1609 protein AL137316 TBC/LysM-associated domain containing 1 TLDC1 57707 NM_020947 /// XM_005256074 /// XM_005256075 /// XM_005256077 /// XM_006721240 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222262_s_at AL137750 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AL137750.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434E1212 (from clone DKFZp434E1212). /FEA=mRNA /DB_XREF=gi:6808386 /UG=Hs.120439 ethanolamine kinase AL137750 ethanolamine kinase 1 ETNK1 55500 NM_001039481 /// NM_018638 /// XM_005253420 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 222263_at BE904333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE904333 /FEA=EST /DB_XREF=gi:10396479 /DB_XREF=est:601496214F1 /CLONE=IMAGE:3898490 /UG=Hs.281462 ESTs BE904333 solute carrier family 35, member E1 SLC35E1 79939 NM_024881 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222264_at BG167570 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG167570 /FEA=EST /DB_XREF=gi:12674199 /DB_XREF=est:602342795F1 /CLONE=IMAGE:4453055 /UG=Hs.321717 ESTs, Weakly similar to S22765 heterogeneous ribonuclear particle protein U H.sapiens BG167570 heterogeneous nuclear ribonucleoprotein U-like 2 HNRNPUL2 221092 NM_001079559 0005634 // nucleus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222265_at BE735851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE735851 /FEA=EST /DB_XREF=gi:10149843 /DB_XREF=est:601305177F1 /CLONE=IMAGE:3639643 /UG=Hs.187745 ESTs, Weakly similar to T17293 hypothetical protein DKFZp434G162.1 H.sapiens BE735851 tensin 4 TNS4 84951 NM_032865 /// XM_005257744 0006915 // apoptotic process // inferred from electronic annotation /// 0008104 // protein localization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222266_at BF796940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF796940 /FEA=EST /DB_XREF=gi:12101994 /DB_XREF=est:602258153F1 /CLONE=IMAGE:4341588 /UG=Hs.294100 ESTs BF796940 222267_at BE619220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE619220 /FEA=EST /DB_XREF=gi:9890158 /DB_XREF=est:601472975F1 /CLONE=IMAGE:3875730 /UG=Hs.267245 ESTs, Weakly similar to cDNA EST EMBL:T02216 comes from this gene C.elegans BE619220 transmembrane protein 209 TMEM209 84928 NM_032842 /// XM_005250655 /// XM_005250657 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222268_x_at AA587390 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA587390 /FEA=EST /DB_XREF=gi:2398204 /DB_XREF=est:nn82h01.s1 /CLONE=IMAGE:1090417 /UG=Hs.321110 ESTs, Highly similar to mucin H.sapiens AA587390 mucin 5B, oligomeric mucus/gel-forming MUC5B 727897 NM_002458 0007155 // cell adhesion // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 222269_at W87634 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W87634 /FEA=EST /DB_XREF=gi:1401698 /DB_XREF=est:zh67b09.s1 /CLONE=IMAGE:417113 /UG=Hs.17947 ESTs, Weakly similar to K02F3.10 C.elegans W87634 apolipoprotein O-like APOOL 139322 NM_198450 /// XM_005262080 0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222270_at BG540048 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG540048 /FEA=EST /DB_XREF=gi:13532281 /DB_XREF=est:602568675F1 /CLONE=IMAGE:4693242 /UG=Hs.293982 ESTs BG540048 SMEK homolog 2, suppressor of mek1 (Dictyostelium) SMEK2 57223 NM_001122964 /// NM_001282850 /// NM_020463 /// XM_005264442 /// XM_005264444 /// XM_005264445 /// XM_005264446 /// XM_005264447 /// XM_005264448 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030289 // protein phosphatase 4 complex // inferred from electronic annotation 222271_at AV720803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV720803 /FEA=EST /DB_XREF=gi:10817955 /DB_XREF=est:AV720803 /CLONE=GLCCMA04 /UG=Hs.293055 ESTs AV720803 222272_x_at BG283584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG283584 /FEA=EST /DB_XREF=gi:13033674 /DB_XREF=est:602407908F1 /CLONE=IMAGE:4520281 /UG=Hs.210473 ESTs, Weakly similar to B Chain B, Carboxy-Terminal Half Of Gelsolin H.sapiens BG283584 scinderin SCIN 85477 NM_001112706 /// NM_033128 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0032330 // regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045010 // actin nucleation // inferred from sequence or structural similarity /// 0045654 // positive regulation of megakaryocyte differentiation // inferred from mutant phenotype /// 0051014 // actin filament severing // inferred from mutant phenotype /// 0051047 // positive regulation of secretion // inferred from sequence or structural similarity /// 0051693 // actin filament capping // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from sequence or structural similarity /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity 222273_at AI419423 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI419423 /FEA=EST /DB_XREF=gi:4265354 /DB_XREF=est:tf28d09.x1 /CLONE=IMAGE:2097521 /UG=Hs.172780 ESTs AI419423 poly(A) polymerase gamma PAPOLG 64895 NM_022894 /// XM_005264500 /// XM_005264501 0006378 // mRNA polyadenylation // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0031123 // RNA 3'-end processing // inferred from electronic annotation /// 0043631 // RNA polyadenylation // inferred from direct assay 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // not recorded /// 0004652 // polynucleotide adenylyltransferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from direct assay 222274_at AW975050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW975050 /FEA=EST /DB_XREF=gi:8166254 /DB_XREF=est:EST387155 /UG=Hs.293892 ESTs, Weakly similar to ALU4_HUMAN ALU SUBFAMILY SB2 SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW975050 zinc finger, DHHC-type containing 8 pseudogene 1 ZDHHC8P1 150244 NM_152509 /// NR_003950 222275_at AI039469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI039469 /FEA=EST /DB_XREF=gi:3278663 /DB_XREF=est:ox41a08.s1 /CLONE=IMAGE:1658870 /UG=Hs.27362 ESTs AI039469 mitochondrial ribosomal protein S30 MRPS30 10884 NM_016640 0006412 // translation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222276_at AA837026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA837026 /FEA=EST /DB_XREF=gi:2912225 /DB_XREF=est:og09c12.s1 /CLONE=IMAGE:1439350 /UG=Hs.163549 ESTs AA837026 methyltransferase like 2B METTL2B 55798 NM_018396 0008152 // metabolic process // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from mutant phenotype /// 0032259 // methylation // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016427 // tRNA (cytosine) methyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation 222277_at BG032839 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG032839 /FEA=EST /DB_XREF=gi:12424547 /DB_XREF=est:602300417F1 /CLONE=IMAGE:4401700 /UG=Hs.293341 ESTs, Weakly similar to CA2B_HUMAN COLLAGEN ALPHA 2(XI) CHAIN PRECURSOR H.sapiens BG032839 C1QTNF9B antisense RNA 1 C1QTNF9B-AS1 542767 NM_001014442 /// NM_001135816 0005737 // cytoplasm // inferred from electronic annotation 222278_at AW969655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW969655 /FEA=EST /DB_XREF=gi:8159499 /DB_XREF=est:EST381732 /UG=Hs.168386 ESTs AW969655 uncharacterized LOC101929726 LOC101929726 101929726 XR_242025 /// XR_249998 /// XR_252012 222279_at AI669379 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI669379 /FEA=EST /DB_XREF=gi:4834153 /DB_XREF=est:ty31g04.x1 /CLONE=IMAGE:2280726 /UG=Hs.178036 ESTs, Moderately similar to RL2B_HUMAN 60S RIBOSOMAL PROTEIN L23A H.sapiens AI669379 HLA-F antisense RNA 1 HLA-F-AS1 285830 NM_001003807 /// NR_026972 /// NR_026973 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 222280_at BG491393 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG491393 /FEA=EST /DB_XREF=gi:13452905 /DB_XREF=est:602535682F1 /CLONE=IMAGE:4684748 /UG=Hs.183110 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens BG491393 uncharacterized LOC100506469 LOC100506469 100506469 NR_038396 222281_s_at AW517716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW517716 /FEA=EST /DB_XREF=gi:7155798 /DB_XREF=est:xs86h03.x1 /CLONE=IMAGE:2776565 /UG=Hs.293472 ESTs AW517716 chromosome 1 open reading frame 186 /// uncharacterized LOC100505650 /// uncharacterized LOC101929219 C1orf186 /// LOC100505650 /// LOC101929219 440712 /// 100505650 /// 101929219 NM_001007544 /// XM_005272738 /// XR_159155 /// XR_171245 /// XR_250935 /// XR_425079 /// XR_431333 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222282_at AV761453 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV761453 /FEA=EST /DB_XREF=gi:10919301 /DB_XREF=est:AV761453 /CLONE=MDSBZA03 /UG=Hs.294014 ESTs AV761453 222283_at BG387770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG387770 /FEA=EST /DB_XREF=gi:13281216 /DB_XREF=est:602412648F1 /CLONE=IMAGE:4521442 /UG=Hs.147025 ESTs, Weakly similar to C57785 zinc finger protein ZNF140 H.sapiens BG387770 zinc finger protein 480 ZNF480 147657 NM_144684 /// XM_005258525 /// XM_006723018 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222284_at AI734111 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI734111 /FEA=EST /DB_XREF=gi:5055224 /DB_XREF=est:nc69e01.y5 /CLONE=IMAGE:771864 /UG=Hs.115670 ESTs AI734111 222285_at AW134608 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW134608 /FEA=EST /DB_XREF=gi:6138154 /DB_XREF=est:UI-H-BI1-abo-e-04-0-UI.s1 /CLONE=IMAGE:2712654 /UG=Hs.168941 ESTs AW134608 immunoglobulin heavy constant delta IGHD 3495 0001895 // retina homeostasis // inferred from expression pattern /// 0002250 // adaptive immune response // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045087 // innate immune response // inferred from direct assay /// 0050829 // defense response to Gram-negative bacterium // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071756 // pentameric IgM immunoglobulin complex // inferred from direct assay /// 0071757 // hexameric IgM immunoglobulin complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003823 // antigen binding // non-traceable author statement /// 0031210 // phosphatidylcholine binding // inferred from direct assay /// 0034987 // immunoglobulin receptor binding // inferred from direct assay /// 0042834 // peptidoglycan binding // inferred from direct assay 222286_at R43279 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:R43279 /FEA=EST /DB_XREF=gi:821386 /DB_XREF=est:yg17c12.s1 /CLONE=IMAGE:32731 /UG=Hs.22574 ESTs R43279 small nuclear RNA activating complex, polypeptide 3, 50kDa SNAPC3 6619 NM_001039697 /// NM_003084 /// XR_428427 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 222287_at AW969675 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW969675 /FEA=EST /DB_XREF=gi:8159519 /DB_XREF=est:EST381752 /UG=Hs.291232 ESTs AW969675 triadin TRDN 10345 NM_001251987 /// NM_001256020 /// NM_001256021 /// NM_001256022 /// NM_006073 /// XM_006715299 /// XM_006715300 /// XM_006715301 /// XM_006715302 /// XM_006715303 /// XM_006715304 /// XM_006715305 /// XM_006715306 /// XM_006715307 /// XM_006715308 /// XM_006715309 /// XM_006715310 /// XM_006715311 /// XM_006715312 /// XM_006715313 /// XM_006715314 /// XM_006715315 /// XM_006715316 /// XM_006715317 /// XM_006715318 /// XR_427959 /// XR_427960 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006936 // muscle contraction // traceable author statement /// 0010649 // regulation of cell communication by electrical coupling // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0051279 // regulation of release of sequestered calcium ion into cytosol // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from sequence or structural similarity /// 0090158 // endoplasmic reticulum membrane organization // inferred from sequence or structural similarity /// 1901846 // positive regulation of cell communication by electrical coupling involved in cardiac conduction // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030314 // junctional membrane complex // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0033018 // sarcoplasmic reticulum lumen // traceable author statement /// 0034704 // calcium channel complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity 222288_at AI004009 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI004009 /FEA=EST /DB_XREF=gi:3213519 /DB_XREF=est:ou03d10.x1 /CLONE=IMAGE:1625203 /UG=Hs.130816 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI004009 222289_at AW149844 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW149844 /FEA=EST /DB_XREF=gi:6197740 /DB_XREF=est:xf42h10.x1 /CLONE=IMAGE:2620771 /UG=Hs.167140 ESTs, Moderately similar to CIKG_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV3.4 H.sapiens AW149844 potassium voltage-gated channel, Shaw-related subfamily, member 2 KCNC2 3747 NM_001260497 /// NM_001260498 /// NM_001260499 /// NM_139136 /// NM_139137 /// NM_153748 /// XM_005268854 /// XM_005268855 /// XM_006719382 /// XM_006719383 /// XM_006719384 /// XM_006719385 /// XM_006719386 /// XM_006719387 /// XM_006719388 /// XM_006719389 /// XM_006719390 0001508 // action potential // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation 0005251 // delayed rectifier potassium channel activity // not recorded 222290_at AA731709 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA731709 /FEA=EST /DB_XREF=gi:2752598 /DB_XREF=est:nw70b11.s1 /CLONE=IMAGE:1251933 /UG=Hs.133517 ESTs AA731709 olfactory receptor, family 2, subfamily A, member 20 pseudogene /// olfactory receptor, family 2, subfamily A, member 9 pseudogene OR2A20P /// OR2A9P 401428 /// 441295 NR_002157 /// NR_002158 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 222291_at AI478795 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI478795 /FEA=EST /DB_XREF=gi:4373608 /DB_XREF=est:tm52d07.x1 /CLONE=IMAGE:2161741 /UG=Hs.41123 ESTs, Moderately similar to T12464 hypothetical protein DKFZp564J102.1 H.sapiens AI478795 family with sequence similarity 149, member A FAM149A 25854 NM_001006655 /// NM_015398 /// XM_005262901 /// XM_005262902 /// XM_005262903 /// XM_005262904 /// XM_005262905 /// XM_005262906 /// XM_005262907 /// XM_005262908 /// XM_005262909 /// XM_005262910 /// XM_005262911 /// XM_005262912 /// XM_005262913 222292_at AW298127 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW298127 /FEA=EST /DB_XREF=gi:6704763 /DB_XREF=est:UI-H-BW0-ajs-e-05-0-UI.s1 /CLONE=IMAGE:2733008 /UG=Hs.118832 ESTs, Highly similar to A60771 B-cell activation protein CD40 precursor H.sapiens AW298127 CD40 molecule, TNF receptor superfamily member 5 CD40 958 NM_001250 /// NM_152854 /// XM_005260617 /// XM_005260618 /// XM_005260619 /// XM_006723889 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043406 // positive regulation of MAP kinase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 222293_at AW204383 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW204383 /FEA=EST /DB_XREF=gi:6503855 /DB_XREF=est:UI-H-BI1-adv-c-03-0-UI.s1 /CLONE=IMAGE:2717957 /UG=Hs.312723 ESTs, Highly similar to F22162 1 H.sapiens AW204383 cell adhesion molecule 4 CADM4 199731 NM_145296 /// XM_005258620 0007155 // cell adhesion // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 222294_s_at AW971415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971415 /FEA=EST /DB_XREF=gi:8161260 /DB_XREF=est:EST383504 /UG=Hs.165337 ESTs AW971415 RAB27A, member RAS oncogene family RAB27A 5873 NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation 222295_x_at AI732770 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732770 /FEA=EST /DB_XREF=gi:5053883 /DB_XREF=est:zx78d05.x5 /CLONE=IMAGE:809865 /UG=Hs.328688 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI732770 222296_at AI668610 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI668610 /FEA=EST /DB_XREF=gi:4827918 /DB_XREF=est:yl56a05.x5 /CLONE=IMAGE:162224 /UG=Hs.32043 ESTs AI668610 222297_x_at AV738806 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV738806 /FEA=EST /DB_XREF=gi:10856387 /DB_XREF=est:AV738806 /CLONE=CBCAWB04 /UG=Hs.317387 ESTs, Weakly similar to RL18_HUMAN 60S RIBOSOMAL PROTEIN L1 H.sapiens AV738806 ribosomal protein L18 pseudogene 10 /// RPL18P10 /// RPL18P10 222298_at AA129909 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA129909 /FEA=EST /DB_XREF=gi:1689667 /DB_XREF=est:zn86f06.r1 /CLONE=IMAGE:565091 /UG=Hs.145357 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AA129909 222299_x_at AW301937 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW301937 /FEA=EST /DB_XREF=gi:6711614 /DB_XREF=est:xr85b03.x1 /CLONE=IMAGE:2766893 /UG=Hs.138036 ESTs AW301937 222300_at BF155672 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF155672 /FEA=EST /DB_XREF=gi:11050855 /DB_XREF=est:QV4-HT0894-290900-399-c04 /UG=Hs.146200 ESTs BF155672 222301_at BF530257 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF530257 /FEA=EST /DB_XREF=gi:11617620 /DB_XREF=est:602071432F1 /CLONE=IMAGE:4214622 /UG=Hs.323838 ESTs, Highly similar to transcriptional acitvator H.sapiens BF530257 chromosome 1 open reading frame 61 C1orf61 10485 NM_006365 /// XM_005244832 /// XM_006711117 /// XM_006711118 /// XM_006711119 /// XR_426755 0005634 // nucleus // inferred from electronic annotation 222302_at BE813017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE813017 /FEA=EST /DB_XREF=gi:10245251 /DB_XREF=est:RC2-AN0062-140800-017-g03 /UG=Hs.124629 ESTs BE813017 RP11-82L18.2 222303_at AV700891 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700891 /FEA=EST /DB_XREF=gi:10302862 /DB_XREF=est:AV700891 /CLONE=GKCBQD03 /UG=Hs.292477 ESTs AV700891 222304_x_at AW514038 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW514038 /FEA=EST /DB_XREF=gi:7152120 /DB_XREF=est:xt79a12.x1 /CLONE=IMAGE:2792638 /UG=Hs.332771 olfactory receptor, family 7, subfamily E, member 47 pseudogene AW514038 olfactory receptor, family 7, subfamily E, member 47 pseudogene OR7E47P 26628 NR_120437 /// NR_120438 /// NR_120439 /// NR_120440 222305_at AW975638 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW975638 /FEA=EST /DB_XREF=gi:8166855 /DB_XREF=est:EST387747 /UG=Hs.293490 ESTs AW975638 hexokinase 2 /// HK2 /// RP11-259N19.1 3099 NM_000189 /// XM_005264280 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // not recorded /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005536 // glucose binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded 222306_at AA521034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA521034 /FEA=EST /DB_XREF=gi:2261577 /DB_XREF=est:aa71b04.s1 /CLONE=IMAGE:826351 /UG=Hs.70834 ESTs AA521034 222307_at AI695595 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI695595 /FEA=EST /DB_XREF=gi:4983495 /DB_XREF=est:we49g06.x1 /CLONE=IMAGE:2344474 /UG=Hs.293219 ESTs AI695595 PDCD4 antisense RNA 1 PDCD4-AS1 282997 NR_026932 222308_x_at AV700403 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV700403 /FEA=EST /DB_XREF=gi:10302374 /DB_XREF=est:AV700403 /CLONE=GKBADA01 /UG=Hs.293673 ESTs AV700403 222309_at AW972292 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW972292 /FEA=EST /DB_XREF=gi:8162138 /DB_XREF=est:EST384381 /UG=Hs.292998 ESTs AW972292 chromosome 6 open reading frame 62 C6orf62 81688 NM_030939 /// XM_005249433 0005622 // intracellular // inferred from direct assay 222310_at AA648521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA648521 /FEA=EST /DB_XREF=gi:2574950 /DB_XREF=est:ns22g08.s1 /CLONE=IMAGE:1184414 /UG=Hs.291979 ESTs, Highly similar to SRA4_HUMAN CTD-BINDING SR-LIKE PROTEIN RA4 H.sapiens AA648521 SR-related CTD-associated factor 4 SCAF4 57466 NM_001145444 /// NM_001145445 /// NM_020706 /// XM_005261017 /// XM_006724035 /// XM_006724036 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222311_s_at AA648521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA648521 /FEA=EST /DB_XREF=gi:2574950 /DB_XREF=est:ns22g08.s1 /CLONE=IMAGE:1184414 /UG=Hs.291979 ESTs, Highly similar to SRA4_HUMAN CTD-BINDING SR-LIKE PROTEIN RA4 H.sapiens AA648521 SR-related CTD-associated factor 4 SCAF4 57466 NM_001145444 /// NM_001145445 /// NM_020706 /// XM_005261017 /// XM_006724035 /// XM_006724036 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 222312_s_at AW969803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW969803 /FEA=EST /DB_XREF=gi:8159647 /DB_XREF=est:EST381881 /UG=Hs.105791 ESTs AW969803 222313_at AW972359 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW972359 /FEA=EST /DB_XREF=gi:8162205 /DB_XREF=est:EST384450 /UG=Hs.293334 ESTs AW972359 222314_x_at AW970881 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW970881 /FEA=EST /DB_XREF=gi:8160726 /DB_XREF=est:EST382964 /UG=Hs.205660 ESTs AW970881 eosinophil granule ontogeny transcript (non-protein coding) EGOT 100126791 NR_004428 222315_at AW972855 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW972855 /FEA=EST /DB_XREF=gi:8162701 /DB_XREF=est:EST384950 /UG=Hs.292853 ESTs AW972855 uncharacterized LOC100996756 LOC100996756 100996756 XR_159169 /// XR_250850 /// XR_250851 /// XR_254350 222316_at AW973253 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW973253 /FEA=EST /DB_XREF=gi:8163100 /DB_XREF=est:EST385351 /UG=Hs.292689 ESTs AW973253 222317_at AA888858 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA888858 /FEA=EST /DB_XREF=gi:3015728 /DB_XREF=est:ak23d05.s1 /CLONE=IMAGE:1406793 /UG=Hs.118567 ESTs AA888858 phosphodiesterase 3B, cGMP-inhibited PDE3B 5140 NM_000922 /// XM_005252972 /// XM_006718249 0001525 // angiogenesis // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from expression pattern /// 0007162 // negative regulation of cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred by curator /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043951 // negative regulation of cAMP-mediated signaling // inferred by curator /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004119 // cGMP-inhibited cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 222318_at AI744673 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI744673 /FEA=EST /DB_XREF=gi:5112883 /DB_XREF=est:wg02f04.x1 /CLONE=IMAGE:2363935 /UG=Hs.186970 ESTs AI744673 zinc finger protein 324B ZNF324B 388569 NM_207395 /// XM_005258914 /// XM_005258915 /// XM_005258916 /// XM_005258917 /// XM_005258918 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222319_at AW970948 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW970948 /FEA=EST /DB_XREF=gi:8160793 /DB_XREF=est:EST383031 /UG=Hs.269403 ESTs AW970948 222320_at AW970584 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW970584 /FEA=EST /DB_XREF=gi:8160429 /DB_XREF=est:EST382665 /UG=Hs.291033 ESTs AW970584 222321_at AI911273 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI911273 /FEA=EST /DB_XREF=gi:5631009 /DB_XREF=est:wg33f09.x1 /CLONE=IMAGE:2366921 /UG=Hs.122158 ESTs AI911273 angiotensin II receptor, type 2 AGTR2 186 NM_000686 0001822 // kidney development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // traceable author statement /// 0001991 // regulation of systemic arterial blood pressure by circulatory renin-angiotensin // inferred from sequence or structural similarity /// 0002018 // renin-angiotensin regulation of aldosterone production // inferred from electronic annotation /// 0002033 // vasodilation by angiotensin involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred by curator /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // inferred from sequence or structural similarity /// 0007263 // nitric oxide mediated signal transduction // inferred by curator /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007420 // brain development // non-traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0010700 // negative regulation of norepinephrine secretion // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // traceable author statement /// 0032304 // negative regulation of icosanoid secretion // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0035566 // regulation of metanephros size // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0035932 // aldosterone secretion // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from electronic annotation /// 0038166 // angiotensin-activated signaling pathway // inferred from physical interaction /// 0038166 // angiotensin-activated signaling pathway // traceable author statement /// 0042312 // regulation of vasodilation // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // non-traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from sequence or structural similarity /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from mutant phenotype /// 0060993 // kidney morphogenesis // inferred from electronic annotation /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 1900116 // extracellular negative regulation of signal transduction // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // traceable author statement 222322_at AI791860 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI791860 /FEA=EST /DB_XREF=gi:5339502 /DB_XREF=est:nc45e08.y5 /CLONE=IMAGE:1011110 /UG=Hs.188710 ESTs AI791860 222323_at AI742810 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI742810 /FEA=EST /DB_XREF=gi:5111098 /DB_XREF=est:wg46e05.x1 /CLONE=IMAGE:2368160 /UG=Hs.131057 ESTs, Moderately similar to CRGD_HUMAN GAMMA CRYSTALLIN D H.sapiens AI742810 crystallin, gamma E, pseudogene CRYGEP 222324_at AI344415 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI344415 /FEA=EST /DB_XREF=gi:4081621 /DB_XREF=est:qp13b08.x1 /CLONE=IMAGE:1917879 /UG=Hs.156082 ESTs AI344415 222325_at AW974812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974812 /FEA=EST /DB_XREF=gi:8166015 /DB_XREF=est:EST386917 /UG=Hs.291971 ESTs AW974812 222326_at AW973834 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW973834 /FEA=EST /DB_XREF=gi:8165022 /DB_XREF=est:EST385936 /UG=Hs.105884 ESTs AW973834 222327_x_at AA459867 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA459867 /FEA=EST /DB_XREF=gi:2184774 /DB_XREF=est:zx51h08.s1 /CLONE=IMAGE:795807 /UG=Hs.306191 olfactory receptor, family 7, subfamily E, member 37 pseudogene AA459867 olfactory receptor, family 7, subfamily E, member 156 pseudogene OR7E156P 283491 NR_002171 222328_x_at AI133721 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI133721 /FEA=EST /DB_XREF=gi:6361037 /DB_XREF=est:HA2346 /UG=Hs.53112 ESTs, Moderately similar to ALU8_HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI133721 222329_x_at AW974816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974816 /FEA=EST /DB_XREF=gi:8166019 /DB_XREF=est:EST386921 /UG=Hs.283517 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW974816 222330_at AW974995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974995 /FEA=EST /DB_XREF=gi:8166198 /DB_XREF=est:EST387100 /UG=Hs.292787 ESTs AW974995 222331_at AV652328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV652328 /FEA=EST /DB_XREF=gi:9873342 /DB_XREF=est:AV652328 /CLONE=GLCCZC01 /UG=Hs.282488 ESTs AV652328 222332_at N58524 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N58524 /FEA=EST /DB_XREF=gi:1202414 /DB_XREF=est:yv73a03.s1 /CLONE=IMAGE:248332 /UG=Hs.53176 ESTs N58524 222333_at AV661533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV661533 /FEA=EST /DB_XREF=gi:9882547 /DB_XREF=est:AV661533 /CLONE=GLCGTD12 /UG=Hs.293637 ESTs AV661533 ALS2 C-terminal like ALS2CL 259173 NM_001190707 /// NM_147129 /// NM_182775 /// NR_033815 /// XM_005265025 /// XM_006713088 /// XM_006713089 /// XM_006713090 /// XM_006713091 /// XM_006713092 /// XM_006713093 /// XM_006713094 /// XM_006713095 /// XM_006713096 /// XR_427263 /// XR_427264 /// XR_427265 0007032 // endosome organization // inferred from genetic interaction /// 0008104 // protein localization // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 222334_at AW979289 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW979289 /FEA=EST /DB_XREF=gi:8170577 /DB_XREF=est:EST391399 /UG=Hs.293472 ESTs AW979289 chromosome 1 open reading frame 186 /// uncharacterized LOC100505650 /// uncharacterized LOC101929219 C1orf186 /// LOC100505650 /// LOC101929219 440712 /// 100505650 /// 101929219 NM_001007544 /// XM_005272738 /// XR_159155 /// XR_171245 /// XR_250935 /// XR_425079 /// XR_431333 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222335_at BG025063 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BG025063 /FEA=EST /DB_XREF=gi:12411278 /DB_XREF=est:602276406F1 /CLONE=IMAGE:4364304 /UG=Hs.44888 ESTs BG025063 222336_at AW974915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974915 /FEA=EST /DB_XREF=gi:8166118 /DB_XREF=est:EST387020 /UG=Hs.116550 ESTs AW974915 small integral membrane protein 14 SMIM14 201895 NM_174921 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 222337_at AW968210 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW968210 /FEA=EST /DB_XREF=gi:8158170 /DB_XREF=est:EST380405 /UG=Hs.293957 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens AW968210 222338_x_at AI375965 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI375965 /FEA=EST /DB_XREF=gi:4175955 /DB_XREF=est:tc24h12.x1 /CLONE=IMAGE:2065607 /UG=Hs.131067 ESTs, Moderately similar to IBA2_HUMAN ITBA2 PROTEIN H.sapiens AI375965 RP11-54K16.2 222339_x_at AI054381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI054381 /FEA=EST /DB_XREF=gi:3322168 /DB_XREF=est:qi64d09.x1 /CLONE=IMAGE:1861265 /UG=Hs.176139 ESTs AI054381 222340_at AW975117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW975117 /FEA=EST /DB_XREF=gi:8166322 /DB_XREF=est:EST387223 /UG=Hs.145501 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW975117 222341_x_at AW973235 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW973235 /FEA=EST /DB_XREF=gi:8163081 /DB_XREF=est:EST385333 /UG=Hs.293697 ESTs AW973235 222342_at AW979196 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW979196 /FEA=EST /DB_XREF=gi:8170484 /DB_XREF=est:EST391306 /UG=Hs.292713 ESTs, Moderately similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW979196 222343_at AA629050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA629050 /FEA=EST /DB_XREF=gi:2541437 /DB_XREF=est:zu84a06.s1 /CLONE=IMAGE:744658 /UG=Hs.50760 ESTs, Highly similar to BimL H.sapiens AA629050 BCL2-like 11 (apoptosis facilitator) BCL2L11 10018 NM_001204106 /// NM_001204107 /// NM_001204108 /// NM_001204109 /// NM_001204110 /// NM_001204111 /// NM_001204112 /// NM_001204113 /// NM_006538 /// NM_138621 /// NM_138622 /// NM_138623 /// NM_138624 /// NM_138625 /// NM_138626 /// NM_138627 /// NM_207002 /// NM_207003 /// XM_005263550 /// XM_005263551 /// XM_005263552 /// XM_005263553 /// XM_005263554 /// XM_005263555 /// XM_005263556 /// XM_005263557 /// XM_005263559 /// XM_005263560 /// XM_005263561 /// XR_244801 /// XR_244802 /// XR_244803 /// XR_244804 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0035148 // tube formation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043583 // ear development // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0046620 // regulation of organ growth // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0060139 // positive regulation of apoptotic process by virus // inferred from electronic annotation /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902110 // positive regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 1902263 // apoptotic process involved in embryonic digit morphogenesis // inferred from electronic annotation /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0097140 // BIM-BCL-xl complex // inferred from direct assay /// 0097141 // BIM-BCL-2 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 222344_at AW972765 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW972765 /FEA=EST /DB_XREF=gi:8162611 /DB_XREF=est:EST384859 /UG=Hs.293299 ESTs AW972765 222345_at BF229395 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF229395 /FEA=EST /DB_XREF=gi:11166291 /DB_XREF=est:MR1-CI0019-260900-001-a11 /UG=Hs.159454 ESTs BF229395 ER membrane protein complex subunit 10 EMC10 284361 NM_175063 /// NM_206538 /// XM_006723162 /// XM_006723163 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 222346_at AI633741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI633741 /FEA=EST /DB_XREF=gi:4685071 /DB_XREF=est:tt28a05.x1 /CLONE=IMAGE:2242064 /UG=Hs.270364 ESTs, Moderately similar to S14458 laminin alpha-1 chain precursor H.sapiens AI633741 laminin, alpha 1 LAMA1 284217 NM_005559 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0009888 // tissue development // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0045198 // establishment of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005604 // basement membrane // inferred from direct assay /// 0005606 // laminin-1 complex // inferred from direct assay /// 0005606 // laminin-1 complex // inferred from physical interaction /// 0005608 // laminin-3 complex // inferred from physical interaction /// 0005615 // extracellular space // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0031012 // extracellular matrix // traceable author statement /// 0043256 // laminin complex // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 222347_at AI050036 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI050036 /FEA=EST /DB_XREF=gi:3299153 /DB_XREF=est:an31a09.x1 /CLONE=IMAGE:1700248 /UG=Hs.190616 ESTs AI050036 222348_at AW971134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971134 /FEA=EST /DB_XREF=gi:8160979 /DB_XREF=est:EST383221 /UG=Hs.292245 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW971134 microtubule associated serine/threonine kinase family member 4 MAST4 375449 NM_001164664 /// NM_001290226 /// NM_001290227 /// NM_001290228 /// NM_015183 /// NM_198828 /// XM_005248498 /// XM_006714602 /// XM_006714603 /// XM_006714604 /// XM_006714605 /// XM_006714606 /// XM_006714607 /// XM_006714608 /// XM_006714609 /// XM_006714610 /// XM_006714611 /// XM_006714612 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222349_x_at AW303476 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW303476 /FEA=EST /DB_XREF=gi:6713165 /DB_XREF=est:xv19e10.x1 /CLONE=IMAGE:2813610 /UG=Hs.132299 ESTs AW303476 ring finger protein 126 pseudogene 1 RNF126P1 376412 NR_002818 222350_at AW969913 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW969913 /FEA=EST /DB_XREF=gi:8159757 /DB_XREF=est:EST381991 /UG=Hs.105121 ESTs AW969913 222351_at AW009884 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW009884 /FEA=EST /DB_XREF=gi:5858662 /DB_XREF=est:ws88g09.x1 /CLONE=IMAGE:2505088 /UG=Hs.168737 ESTs, Highly similar to 2AAB_HUMAN SERINETHREONINE PROTEIN PHOSPHATASE 2A, 65 KDA REGULATORY SUBUNIT A, BETA ISOFORM H.sapiens AW009884 protein phosphatase 2, regulatory subunit A, beta PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 222352_at BE465371 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BE465371 /FEA=EST /DB_XREF=gi:9511146 /DB_XREF=est:hw15c12.x1 /CLONE=IMAGE:3182998 /UG=Hs.227170 ESTs BE465371 F-box protein 31 FBXO31 79791 NM_001282683 /// NM_024735 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction 222353_at AV720842 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV720842 /FEA=EST /DB_XREF=gi:10817994 /DB_XREF=est:AV720842 /CLONE=GLCCOH05 /UG=Hs.282435 ESTs AV720842 LIM domains containing 1 LIMD1 8994 NM_014240 /// XM_005265529 /// XM_005265530 /// XM_006713381 0001666 // response to hypoxia // inferred from direct assay /// 0002076 // osteoblast development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from direct assay /// 0016477 // cell migration // inferred from mutant phenotype /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0035195 // gene silencing by miRNA // inferred from mutant phenotype /// 0035331 // negative regulation of hippo signaling // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000637 // positive regulation of gene silencing by miRNA // inferred from mutant phenotype 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 222354_at AW675655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW675655 /FEA=EST /DB_XREF=gi:7540890 /DB_XREF=est:ba52e01.x1 /CLONE=IMAGE:2900184 /UG=Hs.314158 ESTs AW675655 F11 receptor F11R 50848 NM_016946 /// NM_144501 /// NM_144502 /// NM_144503 /// NM_144504 0006954 // inflammatory response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0070830 // tight junction assembly // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 222355_at H24302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H24302 /FEA=EST /DB_XREF=gi:892997 /DB_XREF=est:ym51a07.s1 /CLONE=IMAGE:51738 /UG=Hs.23127 ESTs H24302 222356_at AW974910 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974910 /FEA=EST /DB_XREF=gi:8166113 /DB_XREF=est:EST387015 /UG=Hs.298138 ESTs AW974910 222357_at AW974823 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974823 /FEA=EST /DB_XREF=gi:8166026 /DB_XREF=est:EST386928 /UG=Hs.105411 ESTs AW974823 zinc finger and BTB domain containing 20 ZBTB20 26137 NM_001164342 /// NM_001164343 /// NM_001164344 /// NM_001164345 /// NM_001164346 /// NM_001164347 /// NM_015642 /// NR_121662 /// XM_005247339 /// XM_005247340 /// XM_005247341 /// XM_005247342 /// XM_005247343 /// XM_006713577 /// XM_006713578 /// XM_006713579 /// XM_006713580 /// XM_006713581 /// XM_006713833 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222358_x_at AI523613 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI523613 /FEA=EST /DB_XREF=gi:4437748 /DB_XREF=est:tg95a07.x1 /CLONE=IMAGE:2116500 /UG=Hs.293495 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AI523613 222359_x_at BF573849 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:BF573849 /FEA=EST /DB_XREF=gi:11647561 /DB_XREF=est:602132053F1 /CLONE=IMAGE:4271340 /UG=Hs.96343 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens BF573849 3-ketodihydrosphingosine reductase KDSR 2531 NM_002035 /// XM_005266677 /// XM_006722433 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006666 // 3-keto-sphinganine metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047560 // 3-dehydrosphinganine reductase activity // inferred from direct assay 222360_at AI291720 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI291720 /FEA=EST /DB_XREF=gi:3934494 /DB_XREF=est:qm80c06.x1 /CLONE=IMAGE:1895050 /UG=Hs.262642 ESTs AI291720 diphthamide biosynthesis 5 DPH5 51611 NM_001077394 /// NM_001077395 /// NM_015958 /// XM_005270938 /// XM_005270939 /// XM_005270941 /// XM_006710683 0008152 // metabolic process // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation 0004164 // diphthine synthase activity // non-traceable author statement /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 222361_at AI433261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI433261 /FEA=EST /DB_XREF=gi:4287937 /DB_XREF=est:ti32f08.x1 /CLONE=IMAGE:2132199 /UG=Hs.23189 ESTs, Moderately similar to TBB2_HUMAN TUBULIN BETA-2 CHAIN H.sapiens AI433261 tubulin, beta pseudogene 5 TUBBP5 643224 NR_027156 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 222362_at H07885 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:H07885 /FEA=EST /DB_XREF=gi:872707 /DB_XREF=est:yl86e07.s1 /CLONE=IMAGE:44926 /UG=Hs.30827 ESTs, Highly similar to insulin receptor substrate like protein H.sapiens H07885 ArfGAP with FG repeats 2 AGFG2 3268 NM_006076 /// XM_005250306 /// XM_006715958 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 222363_at AW979018 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW979018 /FEA=EST /DB_XREF=gi:8170301 /DB_XREF=est:EST391128 /UG=Hs.132670 ESTs AW979018 222364_at AW971205 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971205 /FEA=EST /DB_XREF=gi:8161050 /DB_XREF=est:EST383293 /UG=Hs.114280 ESTs AW971205 solute carrier family 44 (choline transporter), member 1 SLC44A1 23446 NM_001286730 /// NM_022109 /// NM_080546 /// XM_005251855 /// XM_005251857 /// XM_006717027 /// XM_006717028 /// XM_006717029 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015871 // choline transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015220 // choline transmembrane transporter activity // traceable author statement 222365_at AW974666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW974666 /FEA=EST /DB_XREF=gi:8165852 /DB_XREF=est:EST386755 /UG=Hs.293024 ESTs AW974666 tubulin folding cofactor E-like TBCEL 219899 NM_001130047 /// NM_152715 /// XM_005271439 /// XM_005271440 /// XM_005271441 /// XM_005271442 /// XM_005271445 /// XM_005271446 /// XM_006718784 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 222366_at W86781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:W86781 /FEA=EST /DB_XREF=gi:1400509 /DB_XREF=est:zh64a03.s1 /CLONE=IMAGE:416812 /UG=Hs.293736 ESTs W86781 222367_at AI921841 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI921841 /FEA=EST /DB_XREF=gi:5657805 /DB_XREF=est:wp07a09.x1 /CLONE=IMAGE:2464120 /UG=Hs.212670 ESTs AI921841 WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2 /// WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3 WHAMMP2 /// WHAMMP3 339005 /// 440253 NR_003521 /// NR_026589 222368_at AW972351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW972351 /FEA=EST /DB_XREF=gi:8162197 /DB_XREF=est:EST384442 /UG=Hs.293451 ESTs AW972351 222369_at AW971254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971254 /FEA=EST /DB_XREF=gi:8161099 /DB_XREF=est:EST383343 /UG=Hs.178433 ESTs AW971254 N(alpha)-acetyltransferase 40, NatD catalytic subunit NAA40 79829 NM_024771 /// XM_005274295 /// XM_005274296 /// XM_006718689 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 222370_x_at N57781 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:N57781 /FEA=EST /DB_XREF=gi:1201671 /DB_XREF=est:yv56g05.s1 /CLONE=IMAGE:246776 /UG=Hs.269584 ESTs, Weakly similar to ALU5_HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens N57781 222371_at AI732802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI732802 /FEA=EST /DB_XREF=gi:5053915 /DB_XREF=est:ab23e08.x5 /CLONE=IMAGE:841670 /UG=Hs.292679 ESTs AI732802 222372_at AW971248 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW971248 /FEA=EST /DB_XREF=gi:8161093 /DB_XREF=est:EST383337 /UG=Hs.291289 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AW971248 membrane associated guanylate kinase, WW and PDZ domain containing 1 MAGI1 9223 NM_001033057 /// NM_004742 /// NM_015520 /// XM_005265563 /// XM_005265564 /// XM_005265565 /// XM_005265566 /// XM_005265568 /// XM_005265570 /// XM_005265571 /// XM_005265574 /// XM_006713407 /// XM_006713408 /// XM_006713409 /// XM_006713410 /// XM_006713411 /// XM_006713412 /// XM_006713413 /// XM_006713414 0006461 // protein complex assembly // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0070997 // neuron death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0051393 // alpha-actinin binding // inferred from physical interaction 222373_at AV651241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV651241 /FEA=EST /DB_XREF=gi:9872255 /DB_XREF=est:AV651241 /CLONE=GLCCNG03 /UG=Hs.282469 ESTs AV651241 222374_at AI186064 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI186064 /FEA=EST /DB_XREF=gi:3736702 /DB_XREF=est:qe50h05.x1 /CLONE=IMAGE:1742457 /UG=Hs.170212 ESTs, Highly similar to b-TRCP variant E3RS-IkappaB H.sapiens AI186064 beta-transducin repeat containing E3 ubiquitin protein ligase BTRC 8945 NM_001256856 /// NM_003939 /// NM_033637 /// XM_005270264 /// XM_006718054 /// XR_428727 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from direct assay /// 0042753 // positive regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 222375_at AW970944 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW970944 /FEA=EST /DB_XREF=gi:8160789 /DB_XREF=est:EST383027 /UG=Hs.291839 ESTs AW970944 222376_at AV704017 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AV704017 /FEA=EST /DB_XREF=gi:10721338 /DB_XREF=est:AV704017 /CLONE=ADBAOG04 /UG=Hs.15833 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens AV704017 RP11-499E18.1 222377_at AI674138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI674138 /FEA=EST /DB_XREF=gi:4874618 /DB_XREF=est:wd08b06.x1 /CLONE=IMAGE:2327507 /UG=Hs.162247 ESTs, Highly similar to T-box-containing transcriptional activator H.sapiens AI674138 T-box 10 TBX10 347853 NM_005995 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 222378_at AW973791 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW973791 /FEA=EST /DB_XREF=gi:8164978 /DB_XREF=est:EST385892 /UG=Hs.292784 ESTs AW973791 222379_at AI002715 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI002715 /FEA=EST /DB_XREF=gi:3203129 /DB_XREF=est:an20d12.s1 /CLONE=IMAGE:1699223 /UG=Hs.130315 ESTs AI002715 potassium voltage-gated channel, Isk-related family, member 4 KCNE4 23704 NM_080671 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation 222380_s_at AI907083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI907083 /FEA=EST /DB_XREF=gi:6497611 /DB_XREF=est:PM-BT134-050499-650 /UG=Hs.124620 ESTs AI907083 programmed cell death 6 PDCD6 10016 NM_001267556 /// NM_001267557 /// NM_001267558 /// NM_001267559 /// NM_013232 /// NR_073609 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032007 // negative regulation of TOR signaling // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0036324 // vascular endothelial growth factor receptor-2 signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from mutant phenotype 222381_at AI907083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AI907083 /FEA=EST /DB_XREF=gi:6497611 /DB_XREF=est:PM-BT134-050499-650 /UG=Hs.124620 ESTs AI907083 222382_x_at AW206115 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW206115 /FEA=EST /DB_XREF=gi:6505589 /DB_XREF=est:UI-H-BI1-afx-h-03-0-UI.s1 /CLONE=IMAGE:2723549 /UG=Hs.312781 ESTs, Moderately similar to similar to a C.elegans protein encoded in cosmid K12D12(Z49069) H.sapiens AW206115 nucleoporin 205kDa NUP205 23165 NM_015135 /// XM_005250235 0000059 // protein import into nucleus, docking // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 222383_s_at AW003512 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AW003512 /FEA=EST /DB_XREF=gi:5850417 /DB_XREF=est:wq66g08.x1 /CLONE=IMAGE:2476286 /UG=Hs.314067 ESTs, Weakly similar to DAHUAL arachidonate 5-lipoxygenase H.sapiens AW003512 arachidonate lipoxygenase 3 ALOXE3 59344 NM_001165960 /// NM_021628 /// XM_005256745 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // inferred from direct assay /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from sequence or structural similarity /// 0043651 // linoleic acid metabolic process // inferred from direct assay /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0046513 // ceramide biosynthetic process // inferred from sequence or structural similarity /// 0051122 // hepoxilin biosynthetic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051120 // hepoxilin A3 synthase activity // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation 222384_at AA417256 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Consensus includes gb:AA417256 /FEA=EST /DB_XREF=gi:2077373 /DB_XREF=est:zu07e04.s1 /CLONE=IMAGE:731166 /UG=Hs.193769 ESTs AA417256 SMG7 antisense RNA 1 SMG7-AS1 284649 NR_040063 243_g_at M64571 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database M64571 /FEATURE=mRNA /DEFINITION=HUMMAP4 Human microtubule-associated protein 4 mRNA, complete cds M64571 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 266_s_at L33930 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank L33930 /FEATURE= /DEFINITION=HUMCD24B Homo sapiens CD24 signal transducer mRNA, complete cds and 3' region L33930 CD24 molecule CD24 100133941 NM_001291737 /// NM_001291738 /// NM_001291739 /// NM_013230 /// NR_117089 /// NR_117090 /// XM_005278329 0001666 // response to hypoxia // inferred from expression pattern /// 0001775 // cell activation // inferred from direct assay /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred by curator /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0031295 // T cell costimulation // inferred from direct assay /// 0032597 // B cell receptor transport into membrane raft // inferred from direct assay /// 0032600 // chemokine receptor transport out of membrane raft // inferred from sequence or structural similarity /// 0032913 // negative regulation of transforming growth factor beta3 production // inferred from mutant phenotype /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0045730 // respiratory burst // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay 31637_s_at X72631 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X72631:H.sapiens mRNA encoding Rev-ErbAalpha /cds=UNKNOWN /gb=X72631 /gi=732801 /ug=Hs.211606 /len=2335 X72631 nuclear receptor subfamily 1, group D, member 1 /// thyroid hormone receptor, alpha NR1D1 /// THRA 7067 /// 9572 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_021724 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 31799_at AF070618 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF070618:Homo sapiens clone 24627 mRNA sequence /cds=UNKNOWN /gb=AF070618 /gi=3283884 /ug=Hs.14074 /len=1179 AF070618 31807_at AC002985 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U69190:U69190 Homo sapiens cDNA /clone=27655 /gb=U69190 /gi=2739414 /ug=Hs.143187 /len=1795 AC002985 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 DDX49 54555 NM_019070 /// NR_033677 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 31826_at AB014574 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014574:Homo sapiens mRNA for KIAA0674 protein, partial cds /cds=(0,3704) /gb=AB014574 /gi=3327161 /ug=Hs.14799 /len=4263 AB014574 FK506 binding protein 15, 133kDa FKBP15 23307 NM_015258 /// XM_006717018 /// XM_006717019 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 31835_at M13149 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M13149:Human histidine-rich glycoprotein mRNA, complete cds /cds=(121,1698) /gb=M13149 /gi=184391 /ug=Hs.1498 /len=2051 M13149 histidine-rich glycoprotein HRG 3273 NM_000412 /// XM_005247415 0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0002839 // positive regulation of immune response to tumor cell // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010543 // regulation of platelet activation // inferred from sequence or structural similarity /// 0010593 // negative regulation of lamellipodium assembly // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0042730 // fibrinolysis // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from sequence or structural similarity /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050832 // defense response to fungus // inferred from direct assay /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from electronic annotation /// 1900747 // negative regulation of vascular endothelial growth factor signaling pathway // inferred from direct assay /// 2000504 // positive regulation of blood vessel remodeling // inferred from direct assay /// 2001027 // negative regulation of endothelial cell chemotaxis // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0019865 // immunoglobulin binding // inferred from direct assay /// 0020037 // heme binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from direct assay 31837_at U62317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U62317:Chromosome 22q13 BAC Clone CIT987SK-384D8 complete sequence /cds=(0,1739) /gb=U62317 /gi=1399959 /ug=Hs.150540 /len=2557 U62317 lipase maturation factor 2 LMF2 91289 NM_033200 /// XM_005261955 /// XM_006724426 /// XM_006724427 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 31845_at U32645 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U32645:Human myeloid elf-1 like factor (MEF) mRNA, complete cds /cds=(382,2373) /gb=U32645 /gi=1761934 /ug=Hs.151139 /len=4167 U32645 E74-like factor 4 (ets domain transcription factor) ELF4 2000 NM_001127197 /// NM_001421 /// XM_005262389 0001787 // natural killer cell proliferation // inferred from sequence or structural similarity /// 0001866 // NK T cell proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 31846_at AW003733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW003733:ws16b04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2497327 /clone_end=3' /gb=AW003733 /gi=5850649 /ug=Hs.15114 /len=839 AW003733 ras homolog family member D RHOD 29984 NM_014578 /// XM_005273963 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 31861_at L14754 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L14754:Human DNA-binding protein (SMBP2) mRNA, complete cds /cds=(49,3030) /gb=L14754 /gi=401775 /ug=Hs.1521 /len=3892 L14754 immunoglobulin mu binding protein 2 IGHMBP2 3508 NM_002180 /// XM_005273974 /// XM_005273975 /// XM_005273976 /// XM_005273977 /// XR_247198 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // traceable author statement /// 0051260 // protein homooligomerization // inferred from physical interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from sequence or structural similarity /// 0032797 // SMN complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // traceable author statement /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032575 // ATP-dependent 5'-3' RNA helicase activity // inferred from direct assay /// 0043022 // ribosome binding // inferred from direct assay /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 31874_at Y07846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Y07846:H.sapiens mRNA for GAR22 protein /cds=(132,1145) /gb=Y07846 /gi=1666070 /ug=Hs.15346 /len=2238 Y07846 growth arrest-specific 2 like 1 GAS2L1 10634 NM_001278730 /// NM_006478 /// NM_152236 /// NM_152237 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0008093 // cytoskeletal adaptor activity // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 32029_at AC005591 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF017995:Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDK1) mRNA, complete cds /cds=(80,1750) /gb=AF017995 /gi=2407612 /ug=Hs.154729 /len=1891 AC005591 3-phosphoinositide-dependent protein kinase 1-like /// 3-phosphoinositide dependent protein kinase 1 LOC101060747 /// PDPK1 5170 /// 101060747 NM_001261816 /// NM_002613 /// NM_031268 /// XM_003960883 /// XM_005255356 /// XM_005275768 /// XM_006709997 /// XM_006709998 0003323 // type B pancreatic cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0010594 // regulation of endothelial cell migration // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0031295 // T cell costimulation // traceable author statement /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043304 // regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004676 // 3-phosphoinositide-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from mutant phenotype /// 0016301 // kinase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction 32032_at L77566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L77566:Homo sapiens DGS-I mRNA, 3 end /cds=UNKNOWN /gb=L77566 /gi=1377764 /ug=Hs.154879 /len=1698 L77566 DiGeorge syndrome critical region gene 14 /// testis-specific serine kinase 2 DGCR14 /// TSSK2 8220 /// 23617 NM_022719 /// NM_053006 /// XM_005261282 /// XM_006724329 /// XM_006724330 /// XM_006724331 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 32042_at S72904 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. S72904:APK1 antigen=MAb KI recognized [human, ovarian carcinoma cell line OVCAR-3, mRNA, 2444 nt] /cds=(219,1010) /gb=S72904 /gi=633925 /ug=Hs.155185 /len=2425 S72904 ecto-NOX disulfide-thiol exchanger 2 ENOX2 10495 NM_001281736 /// NM_006375 /// NM_182314 /// XM_005262354 /// XM_005262355 0007624 // ultradian rhythm // inferred from direct assay /// 0016049 // cell growth // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 32062_at D25216 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D25216:Human mRNA for KIAA0014 gene, complete cds /cds=(146,1627) /gb=D25216 /gi=434774 /ug=Hs.155650 /len=5323 D25216 leucine rich repeat containing 14 LRRC14 9684 NM_001272036 /// NM_014665 /// XM_005272358 /// XM_005272359 /// XM_005272360 /// XM_005272361 /// XM_006716688 /// XM_006716689 32069_at AB014515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014515:Homo sapiens mRNA for KIAA0615 protein, complete cds /cds=(237,2927) /gb=AB014515 /gi=3327043 /ug=Hs.155972 /len=3319 AB014515 NEDD4 binding protein 1 N4BP1 9683 NM_153029 /// XM_005256262 /// XM_006721351 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 32088_at U79751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U79751:Human basic-leucine zipper nuclear factor (JEM-1) mRNA, complete cds /cds=(403,1605) /gb=U79751 /gi=2257753 /ug=Hs.158205 /len=2730 U79751 basic leucine zipper nuclear factor 1 BLZF1 8548 NM_003666 /// XM_005245561 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 32091_at AB007915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB007915:Homo sapiens mRNA for KIAA0446 protein, complete cds /cds=(3531,4286) /gb=AB007915 /gi=3413853 /ug=Hs.158286 /len=6944 AB007915 solute carrier family 25, member 44 SLC25A44 9673 NM_001135672 /// NM_001286184 /// NM_014655 /// NR_104408 /// NR_104411 /// NR_104412 /// XM_006711657 /// XM_006711658 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 32094_at AB017915 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB017915:Homo sapiens mRNA for condoroitin 6-sulfotransferase, complete cds /cds=(440,1879) /gb=AB017915 /gi=4115403 /ug=Hs.158304 /len=6961 AB017915 carbohydrate (chondroitin 6) sulfotransferase 3 CHST3 9469 NM_004273 /// XM_006718075 0005975 // carbohydrate metabolic process // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0008459 // chondroitin 6-sulfotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0050698 // proteoglycan sulfotransferase activity // inferred from electronic annotation 32099_at D50928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D50928:Human mRNA for KIAA0138 gene, complete cds /cds=(36,2897) /gb=D50928 /gi=1469198 /ug=Hs.159384 /len=3233 D50928 scaffold attachment factor B2 SAFB2 9667 NM_014649 /// XM_005259688 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 320_at D83703 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank D83703 /FEATURE= /DEFINITION=D83703 Homo sapiens mRNA for peroxisome assembly factor-2, complete cds D83703 peroxisomal biogenesis factor 6 PEX6 5190 NM_000287 /// XM_005249180 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016561 // protein import into peroxisome matrix, translocation // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from mutant phenotype 32128_at Y13710 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Y13710:Homo sapiens mRNA for alternative activated macrophage specific CC chemokine 1 /cds=(70,339) /gb=Y13710 /gi=2326515 /ug=Hs.16530 /len=779 Y13710 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) CCL18 6362 NM_002988 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009607 // response to biotic stimulus // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation 32137_at Y14330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF029778:Homo sapiens Jagged2 (JAG2) mRNA, complete cds /cds=(404,4120) /gb=AF029778 /gi=2605944 /ug=Hs.166154 /len=4974 Y14330 jagged 2 JAG2 3714 NM_002226 /// NM_145159 0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007219 // Notch signaling pathway // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern /// 0009912 // auditory receptor cell fate commitment // inferred from sequence or structural similarity /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from direct assay /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from direct assay /// 0030334 // regulation of cell migration // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042492 // gamma-delta T cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from direct assay /// 1990134 // epithelial cell apoptotic process involved in palatal shelf morphogenesis // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005112 // Notch binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay 32209_at AF052151 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF052151:Homo sapiens clone 24574 mRNA sequence /cds=UNKNOWN /gb=AF052151 /gi=3360461 /ug=Hs.18686 /len=1337 AF052151 family with sequence similarity 89, member B FAM89B 23625 NM_001098784 /// NM_001098785 /// NM_152832 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060392 // negative regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation 0001222 // transcription corepressor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 32259_at AB002386 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002386:Human mRNA for KIAA0388 gene, complete cds /cds=(100,2343) /gb=AB002386 /gi=2224716 /ug=Hs.194669 /len=4606 AB002386 enhancer of zeste 1 polycomb repressive complex 2 subunit EZH1 2145 NM_001991 /// XM_005257144 /// XM_005257145 /// XM_005257146 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from electronic annotation 32402_s_at Y10931 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Y10931:H.sapiens mRNA for symplekin /cds=(459,3887) /gb=Y10931 /gi=2143261 /ug=Hs.234780 /len=3984 Y10931 symplekin SYMPK 8189 NM_004819 /// XM_005259286 /// XR_243962 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006398 // histone mRNA 3'-end processing // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 32502_at AL041124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL041124:DKFZp434D0316_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434D0316 /clone_end=3' /gb=AL041124 /gi=5410060 /ug=Hs.6748 /len=719 AL041124 glycerophosphodiester phosphodiesterase domain containing 5 GDPD5 81544 NM_030792 /// XM_006718694 /// XM_006718695 /// XM_006718696 /// XM_006718697 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021522 // spinal cord motor neuron differentiation // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 32540_at AI762547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI762547:wh92e05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2388224 /clone_end=3' /gb=AI762547 /gi=5178214 /ug=Hs.75206 /len=655 AI762547 protein phosphatase 3, catalytic subunit, gamma isozyme PPP3CC 5533 NM_001243974 /// NM_001243975 /// NM_005605 /// XM_005273564 /// XR_428312 0006915 // apoptotic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 32541_at S46622 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. S46622:calcineurin A catalytic subunit [human, testis, mRNA, 2134 nt] /cds=(286,1794) /gb=S46622 /gi=258000 /ug=Hs.75206 /len=2134 S46622 protein phosphatase 3, catalytic subunit, gamma isozyme PPP3CC 5533 NM_001243974 /// NM_001243975 /// NM_005605 /// XM_005273564 /// XR_428312 0006915 // apoptotic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 32625_at X15357 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X15357:Human mRNA for natriuretic peptide receptor (ANP-A receptor) /cds=(43,3228) /gb=X15357 /gi=28229 /ug=Hs.167382 /len=3803 X15357 natriuretic peptide receptor 1 NPR1 4881 NM_000906 /// XM_005245218 /// XM_006711342 /// XM_006711343 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007589 // body fluid secretion // traceable author statement /// 0008217 // regulation of blood pressure // non-traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035810 // positive regulation of urine volume // traceable author statement /// 0035815 // positive regulation of renal sodium excretion // traceable author statement /// 0042312 // regulation of vasodilation // non-traceable author statement /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0043114 // regulation of vascular permeability // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008528 // G-protein coupled peptide receptor activity // non-traceable author statement /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction 32699_s_at X64116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X64116:H.sapiens PVR gene for poliovirus receptor (exon 1) /cds=(205,1299) /gb=X64116 /gi=35809 /ug=Hs.171844 /len=1300 X64116 poliovirus receptor PVR 5817 NM_001135768 /// NM_001135769 /// NM_001135770 /// NM_006505 /// XM_005259120 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050776 // regulation of immune response // traceable author statement /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 32723_at L02547 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L02547:Homo sapiens (clone pZ50-19) cleavage stimulation factor 50kDa subunit, complete cds /cds=(181,1476) /gb=L02547 /gi=180598 /ug=Hs.172865 /len=1801 L02547 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa CSTF1 1477 NM_001033521 /// NM_001033522 /// NM_001324 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 32811_at X98507 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X98507:H.sapiens mRNA for myosin-I beta /cds=(65,3151) /gb=X98507 /gi=1926310 /ug=Hs.202788 /len=3384 X98507 myosin IC MYO1C 4641 NM_001080779 /// NM_001080950 /// NM_033375 /// XM_005256655 0006605 // protein targeting // inferred from direct assay /// 0006612 // protein targeting to membrane // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0038089 // positive regulation of cell migration by vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from mutant phenotype /// 1900748 // positive regulation of vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 2000810 // regulation of tight junction assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005903 // brush border // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045160 // myosin I complex // inferred from electronic annotation /// 0060171 // stereocilium membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 32836_at U56417 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U56417:Human lysophosphatidic acid acyltransferase-alpha mRNA, complete cds /cds=(318,1169) /gb=U56417 /gi=2155237 /ug=Hs.209119 /len=2232 U56417 1-acylglycerol-3-phosphate O-acyltransferase 1 AGPAT1 10554 NM_006411 /// NM_032741 /// XM_005248805 /// XM_005248806 /// XM_005272761 /// XM_005272762 /// XM_005274829 /// XM_005274830 /// XM_005275073 /// XM_005275074 /// XM_005275203 /// XM_005275204 /// XM_005275337 /// XM_005275338 /// XM_005275504 /// XM_005275505 0001819 // positive regulation of cytokine production // inferred from mutant phenotype /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred by curator /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // inferred from genetic interaction /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from genetic interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 32837_at U56418 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U56418:Human lysophosphatidic acid acyltransferase-beta mRNA, complete cds /cds=(39,875) /gb=U56418 /gi=2155239 /ug=Hs.209119 /len=1356 U56418 1-acylglycerol-3-phosphate O-acyltransferase 2 AGPAT2 10555 NM_001012727 /// NM_006412 0001819 // positive regulation of cytokine production // inferred from mutant phenotype /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred by curator /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // inferred from genetic interaction /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from genetic interaction /// 0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation 33132_at U37012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U37012:Human cleavage and polyadenylation specificity factor mRNA, complete cds /cds=(51,4379) /gb=U37012 /gi=1045573 /ug=Hs.83727 /len=4463 U37012 cleavage and polyadenylation specific factor 1, 160kDa /// microRNA 1234 /// microRNA 6849 /// microRNA 939 CPSF1 /// MIR1234 /// MIR6849 /// MIR939 29894 /// 100126351 /// 100302196 /// 102466749 NM_013291 /// NR_030635 /// NR_031600 /// NR_106908 /// XM_006716548 /// XM_006716549 /// XM_006716550 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 33148_at AI459274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI459274:tk11f11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2150733 /clone_end=3' /gb=AI459274 /gi=4311853 /ug=Hs.87150 /len=687 AI459274 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 33197_at U39226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U39226:Human myosin VIIA (USH1B) mRNA, complete cds /cds=(272,6919) /gb=U39226 /gi=1235669 /ug=Hs.95361 /len=7465 U39226 myosin VIIA MYO7A 4647 NM_000260 /// NM_001127179 /// NM_001127180 /// XM_005274012 /// XM_006718558 /// XM_006718559 /// XM_006718560 /// XM_006718561 0001845 // phagolysosome assembly // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007600 // sensory perception // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from direct assay /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from direct assay /// 0042462 // eye photoreceptor cell development // inferred by curator /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042490 // mechanoreceptor differentiation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0048563 // post-embryonic organ morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0050957 // equilibrioception // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation 0001750 // photoreceptor outer segment // inferred from direct assay /// 0001917 // photoreceptor inner segment // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0031477 // myosin VII complex // inferred from electronic annotation /// 0032391 // photoreceptor connecting cilium // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0000146 // microfilament motor activity // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from reviewed computational analysis /// 0051015 // actin filament binding // inferred from direct assay 33304_at U88964 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U88964:Human HEM45 mRNA, complete cds /cds=(37,582) /gb=U88964 /gi=2062679 /ug=Hs.183487 /len=701 U88964 interferon stimulated exonuclease gene 20kDa ISG20 3669 NM_002201 /// XM_005254899 /// XM_005254900 /// XM_006720488 /// XM_006720489 /// XM_006720490 0000738 // DNA catabolic process, exonucleolytic // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006401 // RNA catabolic process // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from mutant phenotype /// 0008310 // single-stranded DNA 3'-5' exodeoxyribonuclease activity // inferred from direct assay /// 0008859 // exoribonuclease II activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030619 // U1 snRNA binding // inferred from direct assay /// 0030620 // U2 snRNA binding // inferred from direct assay /// 0034511 // U3 snoRNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 33307_at AL022316 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL022316:Human DNA sequence from clone 126B4 on chromosome 22q13.2-13.31. Contains two or three novel genes, ESTs, STSs and GSSs /cds=(0,842) /gb=AL022316 /gi=4691242 /ug=Hs.183807 /len=1191 AL022316 ribosomal RNA processing 7 homolog A (S. cerevisiae) RRP7A 27341 NM_015703 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 33322_i_at X57348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X57348:H.sapiens mRNA (clone 9112) /cds=(165,911) /gb=X57348 /gi=23939 /ug=Hs.184510 /len=1407 X57348 stratifin SFN 2810 NM_006142 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045606 // positive regulation of epidermal cell differentiation // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 33323_r_at X57348 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X57348:H.sapiens mRNA (clone 9112) /cds=(165,911) /gb=X57348 /gi=23939 /ug=Hs.184510 /len=1407 X57348 stratifin SFN 2810 NM_006142 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045606 // positive regulation of epidermal cell differentiation // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 33494_at S69232 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. S69232:electron transfer flavoprotein-ubiquinone oxidoreductase [human, fetal liver, mRNA, 2124 nt] /cds=(120,1973) /gb=S69232 /gi=545620 /ug=Hs.30661 /len=2113 S69232 electron-transferring-flavoprotein dehydrogenase ETFDH 2110 NM_001281737 /// NM_001281738 /// NM_004453 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0022900 // electron transport chain // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay 0004174 // electron-transferring-flavoprotein dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0043783 // oxidoreductase activity, oxidizing metal ions with flavin as acceptor // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from direct assay /// 0048039 // ubiquinone binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from direct assay 33579_i_at Z97630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z97630:Human DNA sequence from clone 466N1 on chromosome 22q12-13 Contains H1F0(H1 histone family, member 0) gene, 2-amino-3-ketobutyrate -CoA ligase( nuclear gene encoding mitochondrial protein), GALR3 (galanin receptor) gene, ESTs, GSSs and CpG islands /cds=(25,1131) /gb=Z97630 /gi=4582128 /ug=Hs.158353 /len=1157 Z97630 galanin receptor 3 GALR3 8484 NM_003614 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // traceable author statement /// 0007631 // feeding behavior // traceable author statement /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004966 // galanin receptor activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from direct assay 33646_g_at X61094 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X61094:H.sapiens RNA for GM2-activator protein (clone pGM2A) /cds=(0,312) /gb=X61094 /gi=31854 /ug=Hs.169293 /len=648 X61094 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019377 // glycolipid catabolic process // non-traceable author statement /// 0019915 // lipid storage // inferred from electronic annotation /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030290 // sphingolipid activator protein activity // non-traceable author statement 336_at D38081 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank D38081 /FEATURE= /DEFINITION=HUMHTAR Human mRNA for thromboxane A2 receptor, complete cds D38081 thromboxane A2 receptor TBXA2R 6915 NM_001060 /// NM_201636 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0019932 // second-messenger-mediated signaling // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0038193 // thromboxane A2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004960 // thromboxane receptor activity // inferred from electronic annotation /// 0004961 // thromboxane A2 receptor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 33736_at Y16522 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Y16522:Homo sapiens mRNA for hSLP-1 protein /cds=(44,1228) /gb=Y16522 /gi=4160545 /ug=Hs.194816 /len=1945 Y16522 stomatin (EPB72)-like 1 STOML1 9399 NM_001256672 /// NM_001256673 /// NM_001256674 /// NM_001256675 /// NM_001256676 /// NM_001256677 /// NM_004809 /// XM_005254792 /// XM_005254793 /// XM_006720771 /// XM_006720772 /// XM_006720773 /// XM_006720774 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032934 // sterol binding // inferred from electronic annotation 33760_at AB017546 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB017546:Homo sapiens Pex14 mRNA for peroxisomal membrane anchor protein, complete cds /cds=(5,1138) /gb=AB017546 /gi=4126965 /ug=Hs.19851 /len=1908 AB017546 peroxisomal biogenesis factor 14 PEX14 5195 NM_004565 /// XM_005263470 /// XM_006710685 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from genetic interaction /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016560 // protein import into peroxisome matrix, docking // inferred from electronic annotation /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from direct assay /// 0036250 // peroxisome transport along microtubule // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0044721 // protein import into peroxisome matrix, substrate release // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from physical interaction 33767_at X15306 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X15306:H.sapiens NF-H gene, exon 1 (and joined CDS) /cds=(0,3062) /gb=X15306 /gi=35028 /ug=Hs.198760 /len=3750 X15306 neurofilament, heavy polypeptide NEFH 4744 NM_021076 /// XM_005261619 /// XM_006724257 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007409 // axonogenesis // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0030031 // cell projection assembly // traceable author statement /// 0033693 // neurofilament bundle assembly // inferred from mutant phenotype /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045110 // intermediate filament bundle assembly // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation /// 0061564 // axon development // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005883 // neurofilament // non-traceable author statement /// 0030424 // axon // traceable author statement /// 0097418 // neurofibrillary tangle // inferred from direct assay 0005198 // structural molecule activity // inferred from mutant phenotype /// 0005200 // structural constituent of cytoskeleton // inferred from sequence or structural similarity /// 0008017 // microtubule binding // traceable author statement /// 0019894 // kinesin binding // traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0045502 // dynein binding // traceable author statement 33768_at L19267 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L19267:Homo sapiens 59 protein mRNA, 3 end /cds=(0,1661) /gb=L19267 /gi=306711 /ug=Hs.198836 /len=2894 L19267 dystrophia myotonica, WD repeat containing DMWD 1762 NM_004943 0007126 // meiotic nuclear division // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation 33778_at AL096779 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL096779:Novel human gene mapping to chomosome 2213.3 similar to yeast ORF YOR070C, putative GTPase Activator (start missing) /cds=(51,917) /gb=AL096779 /gi=5420221 /ug=Hs.20017 /len=1416 AL096779 TBC1 domain family, member 22A TBC1D22A 25771 NM_001284303 /// NM_001284304 /// NM_001284305 /// NM_014346 /// NR_104292 /// XM_005261496 /// XM_006724223 /// XR_244364 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 33814_at AF005046 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF005046:Homo sapiens serine/threonine kinase mRNA, complete cds /cds=(210,1985) /gb=AF005046 /gi=4101586 /ug=Hs.20447 /len=2811 AF005046 p21 protein (Cdc42/Rac)-activated kinase 4 PAK4 10298 NM_001014831 /// NM_001014832 /// NM_001014833 /// NM_001014834 /// NM_001014835 /// NM_005884 /// XM_006722971 /// XM_006722972 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 33850_at W28892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W28892:53c11 Homo sapiens cDNA /gb=W28892 /gi=1308840 /ug=Hs.239298 /len=926 W28892 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 34031_i_at U90269 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U90268:Human Krit1 mRNA, complete cds /cds=(25,1614) /gb=U90268 /gi=2149601 /ug=Hs.93810 /len=1986 U90269 KRIT1, ankyrin repeat containing KRIT1 889 NM_001013406 /// NM_004912 /// NM_194454 /// NM_194455 /// NM_194456 /// XM_005250660 /// XM_005250662 /// XM_005250663 /// XM_005250664 /// XM_005250665 /// XM_005250666 /// XM_005250667 /// XM_005250668 /// XM_005250669 /// XM_006716160 /// XM_006716161 /// XM_006716162 /// XM_006716163 /// XM_006716164 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 34063_at AB006533 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB006533:Homo sapiens RecQ5 mRNA for DNA helicase, complete cds /cds=(0,1232) /gb=AB006533 /gi=4191811 /ug=Hs.194717 /len=1233 AB006533 RecQ protein-like 5 RECQL5 9400 NM_001003715 /// NM_001003716 /// NM_004259 /// XM_005257818 /// XM_005257822 /// XM_005257823 /// XM_006722186 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // non-traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // non-traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051304 // chromosome separation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 34187_at D28483 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D28483:Human scr3 mRNA for RNA binding protein SCR3, complete cds /cds=(16,1239) /gb=D28483 /gi=520589 /ug=Hs.20938 /len=1509 D28483 RNA binding motif, single stranded interacting protein 2 RBMS2 5939 NM_002898 /// XM_005269059 /// XM_005269060 /// XM_005269061 /// XM_005269066 /// XM_006719541 /// XM_006719542 /// XM_006719543 /// XM_006719544 /// XM_006719545 0006396 // RNA processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 34206_at AB018325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB018325:Homo sapiens mRNA for KIAA0782 protein, partial cds /cds=(0,3540) /gb=AB018325 /gi=3882284 /ug=Hs.21264 /len=4130 AB018325 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ARAP1 116985 NM_001040118 /// NM_001135190 /// NM_015242 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030037 // actin filament reorganization involved in cell cycle // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051270 // regulation of cellular component movement // inferred from mutant phenotype /// 0051491 // positive regulation of filopodium assembly // inferred from mutant phenotype /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 34210_at N90866 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N90866:zb11b10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-301723 /clone_end=3' /gb=N90866 /gi=1444193 /ug=Hs.214742 /len=577 N90866 CD52 molecule CD52 1043 NM_001803 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0045730 // respiratory burst // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation 34221_at D83778 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D83778:Human mRNA for KIAA0194 gene, partial cds /cds=(0,4309) /gb=D83778 /gi=1228038 /ug=Hs.216958 /len=5245 D83778 HMG box domain containing 3 HMGXB3 22993 NM_014983 /// XM_006714765 /// XM_006714766 /// XM_006714767 0016310 // phosphorylation // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0016301 // kinase activity // non-traceable author statement 34225_at AF101434 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF101434:Homo sapiens Wolf-Hirschhorn syndrome candidate 2 protein (WHSC2) mRNA, complete cds /cds=(14,1591) /gb=AF101434 /gi=3860186 /ug=Hs.21771 /len=2190 AF101434 microRNA 943 /// negative elongation factor complex member A MIR943 /// NELFA 7469 /// 100126332 NM_005663 /// NR_030641 /// XM_006713916 /// XM_006713917 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 34260_at AB014583 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014583:Homo sapiens mRNA for KIAA0683 protein, complete cds /cds=(276,2030) /gb=AB014583 /gi=3327179 /ug=Hs.226275 /len=4337 AB014583 telomere maintenance 2 TELO2 9894 NM_016111 /// XM_006720993 /// XR_429650 0032006 // regulation of TOR signaling // inferred from mutant phenotype 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031931 // TORC1 complex // inferred from direct assay /// 0031932 // TORC2 complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation 34406_at AB011174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB011174:Homo sapiens mRNA for KIAA0602 protein, partial cds /cds=(0,2889) /gb=AB011174 /gi=3043727 /ug=Hs.37656 /len=3428 AB011174 phosphofurin acidic cluster sorting protein 2 PACS2 23241 NM_001100913 /// NM_001243127 /// NM_015197 /// XM_005267462 /// XM_005267463 /// XM_006720085 /// XM_006720086 /// XM_006720087 /// XM_006720088 /// XM_006720089 /// XM_006720090 /// XM_006720091 /// XM_006720092 0006915 // apoptotic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 34408_at AF004222 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF004222:Homo sapiens RTN2-A (RTN2) mRNA, complete cds /cds=(129,1766) /gb=AF004222 /gi=3435085 /ug=Hs.3803 /len=2177 AF004222 reticulon 2 RTN2 6253 NM_005619 /// NM_206900 /// NM_206901 /// NM_206902 /// XR_243948 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0014802 // terminal cisterna // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0030315 // T-tubule // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 34449_at U13022 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U13022:Human negative regulator of programmed cell death ICH-1S (Ich-1) mRNA, complete cds /cds=(88,1026) /gb=U13022 /gi=537293 /ug=Hs.108131 /len=2167 U13022 caspase 2, apoptosis-related cysteine peptidase CASP2 835 NM_001224 /// NM_032982 /// NM_032983 0001554 // luteolysis // inferred from electronic annotation /// 0003407 // neural retina development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation 34471_at M36769 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M36769:Homo sapiens perinatal myosin heavy chain mRNA, complete cds /cds=(73,5886) /gb=M36769 /gi=189033 /ug=Hs.113973 /len=6016 M36769 myosin, heavy chain 8, skeletal muscle, perinatal MYH8 4626 NM_002472 0003009 // skeletal muscle contraction // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006936 // muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030049 // muscle filament sliding // inferred from mutant phenotype /// 0030049 // muscle filament sliding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030017 // sarcomere // inferred by curator /// 0032982 // myosin filament // inferred by curator 0000146 // microfilament motor activity // inferred from mutant phenotype /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0016887 // ATPase activity // inferred from mutant phenotype /// 0032027 // myosin light chain binding // traceable author statement /// 0051015 // actin filament binding // traceable author statement 34478_at X79780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X79780:H.sapiens YPT3 mRNA /cds=(6,662) /gb=X79780 /gi=763129 /ug=Hs.115279 /len=701 X79780 RAB11B, member RAS oncogene family RAB11B 9230 NM_004218 0001881 // receptor recycling // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0033572 // transferrin transport // inferred from sequence or structural similarity /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0044070 // regulation of anion transport // inferred from mutant phenotype /// 0045054 // constitutive secretory pathway // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0071468 // cellular response to acidity // inferred from direct assay /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype /// 2001135 // regulation of endocytic recycling // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 34689_at AJ243797 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AJ243797:Homo sapiens mRNA for deoxyribonuclease III (drn3 gene) /cds=(256,1170) /gb=AJ243797 /gi=5524926 /ug=Hs.23595 /len=1239 AJ243797 ATR interacting protein /// three prime repair exonuclease 1 ATRIP /// TREX1 11277 /// 84126 NM_001271022 /// NM_001271023 /// NM_007248 /// NM_016381 /// NM_032166 /// NM_033627 /// NM_033628 /// NM_033629 /// NM_130384 0000077 // DNA damage checkpoint // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0000738 // DNA catabolic process, exonucleolytic // inferred from sequence or structural similarity /// 0000738 // DNA catabolic process, exonucleolytic // traceable author statement /// 0006259 // DNA metabolic process // inferred from sequence or structural similarity /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008296 // 3'-5'-exodeoxyribonuclease activity // inferred from sequence or structural similarity /// 0008408 // 3'-5' exonuclease activity // inferred from direct assay /// 0008408 // 3'-5' exonuclease activity // traceable author statement /// 0008853 // exodeoxyribonuclease III activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0032407 // MutSalpha complex binding // inferred from direct assay /// 0032558 // adenyl deoxyribonucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // non-traceable author statement /// 0046872 // metal ion binding // traceable author statement 34697_at AF074264 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF074264:Homo sapiens LDL receptor-related protein 6 (LRP6) mRNA, complete cds /cds=(77,4918) /gb=AF074264 /gi=3462526 /ug=Hs.23672 /len=5288 AF074264 low density lipoprotein receptor-related protein 6 LRP6 4040 NM_002336 /// XM_006719078 /// XR_429034 /// XR_429035 0001702 // gastrulation with mouth forming second // not recorded /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // not recorded /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003344 // pericardium morphogenesis // not recorded /// 0003401 // axis elongation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007268 // synaptic transmission // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // not recorded /// 0009950 // dorsal/ventral axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // not recorded /// 0014029 // neural crest formation // inferred from direct assay /// 0014033 // neural crest cell differentiation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // not recorded /// 0021794 // thalamus development // not recorded /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from electronic annotation /// 0021872 // forebrain generation of neurons // inferred from electronic annotation /// 0021874 // Wnt signaling pathway involved in forebrain neuroblast division // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021943 // formation of radial glial scaffolds // inferred from electronic annotation /// 0021987 // cerebral cortex development // not recorded /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030278 // regulation of ossification // not recorded /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // not recorded /// 0030917 // midbrain-hindbrain boundary development // not recorded /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from mutant phenotype /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035261 // external genitalia morphogenesis // not recorded /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0042074 // cell migration involved in gastrulation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // not recorded /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044332 // Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 0044335 // canonical Wnt signaling pathway involved in neural crest cell differentiation // inferred by curator /// 0044340 // canonical Wnt signaling pathway involved in regulation of cell proliferation // inferred by curator /// 0045598 // regulation of fat cell differentiation // not recorded /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046849 // bone remodeling // not recorded /// 0048596 // embryonic camera-type eye morphogenesis // not recorded /// 0048699 // generation of neurons // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051593 // response to folic acid // inferred from electronic annotation /// 0060021 // palate development // not recorded /// 0060026 // convergent extension // not recorded /// 0060042 // retina morphogenesis in camera-type eye // inferred from electronic annotation /// 0060059 // embryonic retina morphogenesis in camera-type eye // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060284 // regulation of cell development // inferred from electronic annotation /// 0060325 // face morphogenesis // not recorded /// 0060349 // bone morphogenesis // not recorded /// 0060444 // branching involved in mammary gland duct morphogenesis // not recorded /// 0060535 // trachea cartilage morphogenesis // not recorded /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation /// 0061310 // canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development // inferred from electronic annotation /// 0061324 // canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from mutant phenotype /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090009 // primitive streak formation // not recorded /// 0090118 // receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport // not recorded /// 0090244 // Wnt signaling pathway involved in somitogenesis // not recorded /// 0090245 // axis elongation involved in somitogenesis // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1901998 // toxin transport // inferred from mutant phenotype /// 2000051 // negative regulation of non-canonical Wnt signaling pathway // inferred from electronic annotation /// 2000055 // positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000149 // negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis // inferred from electronic annotation /// 2000151 // negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 2000162 // negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis // inferred from electronic annotation /// 2000164 // negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis // inferred from electronic annotation /// 2000166 // negative regulation of planar cell polarity pathway involved in pericardium morphogenesis // inferred from electronic annotation /// 2000168 // negative regulation of planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043025 // neuronal cell body // not recorded /// 0043235 // receptor complex // not recorded /// 0045202 // synapse // not recorded 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0019210 // kinase inhibitor activity // inferred from mutant phenotype /// 0019534 // toxin transporter activity // inferred from mutant phenotype /// 0034185 // apolipoprotein binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0071936 // coreceptor activity involved in Wnt signaling pathway // inferred from direct assay 34726_at U07139 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U07139:Human voltage-gated calcium channel beta subunit mRNA, complete cds /cds=(34,1488) /gb=U07139 /gi=463890 /ug=Hs.239447 /len=2532 U07139 calcium channel, voltage-dependent, beta 3 subunit CACNB3 784 NM_000725 /// NM_001206915 /// NM_001206916 /// NM_001206917 /// XM_005269142 /// XM_006719590 /// XM_006719591 /// XM_006719592 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 34764_at D21851 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D21851:Human mRNA for KIAA0028 gene, partial cds /cds=(185,2896) /gb=D21851 /gi=434766 /ug=Hs.2450 /len=4203 D21851 leucyl-tRNA synthetase 2, mitochondrial LARS2 23395 NM_015340 /// XM_005265006 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006429 // leucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004823 // leucine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 34846_at AF112472 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF112472:Homo sapiens calcium/calmodulin-dependent protein kinase II beta subunit mRNA, complete cds /cds=(46,1674) /gb=AF112472 /gi=4139269 /ug=Hs.4884 /len=1825 AF112472 calcium/calmodulin-dependent protein kinase II beta CAMK2B 816 NM_001220 /// NM_001293170 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 /// XM_005249859 /// XM_005249861 /// XM_005249862 /// XM_005249864 /// XM_006715776 /// XM_006715777 /// XM_006715778 /// XM_006715779 /// XM_006715780 /// XM_006715781 /// XM_006715782 /// XM_006715783 /// XM_006715784 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0002030 // inhibitory G-protein coupled receptor phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0014733 // regulation of skeletal muscle adaptation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032222 // regulation of synaptic transmission, cholinergic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048169 // regulation of long-term neuronal synaptic plasticity // traceable author statement /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051823 // regulation of synapse structural plasticity // traceable author statement /// 0051924 // regulation of calcium ion transport // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060466 // activation of meiosis involved in egg activation // inferred from electronic annotation /// 0060998 // regulation of dendritic spine development // traceable author statement /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0051233 // spindle midzone // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 34858_at D79998 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D79998:Human mRNA for KIAA0176 gene, partial cds /cds=(0,797) /gb=D79998 /gi=1136411 /ug=Hs.4935 /len=3635 D79998 potassium channel tetramerization domain containing 2 KCTD2 23510 NM_015353 /// NR_110834 /// NR_110835 /// XR_243758 /// XR_248405 /// XR_253732 0051260 // protein homooligomerization // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 34868_at AB029012 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB029012:Homo sapiens mRNA for KIAA1089 protein, partial cds /cds=(0,2967) /gb=AB029012 /gi=5689514 /ug=Hs.4990 /len=4329 AB029012 SMG5 nonsense mediated mRNA decay factor SMG5 23381 NM_015327 /// XM_005245049 /// XM_006711248 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 35147_at AB002360 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002360:Human mRNA for KIAA0362 gene, partial cds /cds=(0,3327) /gb=AB002360 /gi=2224664 /ug=Hs.25515 /len=5391 AB002360 MCF.2 cell line derived transforming sequence-like MCF2L 23263 NM_001112732 /// NM_024979 /// XM_005268307 /// XM_005268308 /// XM_005268309 /// XM_005268310 /// XM_005268312 /// XM_005268313 /// XM_005268314 /// XM_005268315 /// XM_005268316 /// XM_006719966 /// XM_006719967 /// XM_006719968 /// XR_429282 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from electronic annotation 35148_at AC005954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AC005954:Homo sapiens chromosome 19, cosmid R28784 /cds=(0,2858) /gb=AC005954 /gi=3851201 /ug=Hs.25527 /len=2859 AC005954 tight junction protein 3 TJP3 27134 NM_001267560 /// NM_001267561 /// NM_014428 /// XM_005259539 /// XM_006722724 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 35150_at X60592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X60592:Human CDw40 mRNA for nerve growth factor receptor-related B-lymphocyte activation molecule /cds=(47,880) /gb=X60592 /gi=29850 /ug=Hs.25648 /len=1004 X60592 CD40 molecule, TNF receptor superfamily member 5 CD40 958 NM_001250 /// NM_152854 /// XM_005260617 /// XM_005260618 /// XM_005260619 /// XM_006723889 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0042100 // B cell proliferation // non-traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043406 // positive regulation of MAP kinase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048304 // positive regulation of isotype switching to IgG isotypes // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051023 // regulation of immunoglobulin secretion // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090037 // positive regulation of protein kinase C signaling // inferred from mutant phenotype /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 35156_at AL050297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL050297:Homo sapiens mRNA; cDNA DKFZp564N123 (from clone DKFZp564N123) /cds=UNKNOWN /gb=AL050297 /gi=4886448 /ug=Hs.25894 /len=1340 AL050297 R3H domain and coiled-coil containing 1 R3HCC1 203069 NM_001136108 /// XM_005273427 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation 35160_at AF064491 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF064491:Homo sapiens LIM homeobox protein cofactor (CLIM2) mRNA, complete cds /cds=(313,1440) /gb=AF064491 /gi=3372806 /ug=Hs.26002 /len=1965 AF064491 LIM domain binding 1 LDB1 8861 NM_001113407 /// NM_003893 /// XM_005270262 0000972 // transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery // inferred from sequence or structural similarity /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0022607 // cellular component assembly // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043973 // histone H3-K4 acetylation // inferred from sequence or structural similarity /// 0045647 // negative regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046985 // positive regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060322 // head development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043621 // protein self-association // inferred from electronic annotation 35179_at AB009598 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB009598:Homo sapiens mRNA for glucuronyltransferase I, complete cds /cds=(29,1036) /gb=AB009598 /gi=3892639 /ug=Hs.26492 /len=1441 AB009598 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) B3GAT3 26229 NM_001288721 /// NM_001288722 /// NM_001288723 /// NM_012200 /// NR_109991 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015018 // galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity // non-traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 35201_at X16135 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X16135:Human mRNA for novel heterogeneous nuclear RNP protein, L protein /cds=(28,1704) /gb=X16135 /gi=32355 /ug=Hs.2730 /len=2033 X16135 heterogeneous nuclear ribonucleoprotein L HNRNPL 3191 NM_001005335 /// NM_001533 /// XR_243927 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 35254_at AB007447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB007447:Homo sapiens mRNA for Fln29, complete cds /cds=(54,1802) /gb=AB007447 /gi=2463530 /ug=Hs.5148 /len=2618 AB007447 TRAF-type zinc finger domain containing 1 TRAFD1 10906 NM_001143906 /// NM_006700 0034097 // response to cytokine // inferred from electronic annotation /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 35265_at AF044263 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U31501:Human fragile X mental retardation syndrome related protein (FXR2) mRNA, complete cds /cds=(227,2248) /gb=U31501 /gi=1098636 /ug=Hs.52788 /len=2849 AF044263 fragile X mental retardation, autosomal homolog 2 FXR2 9513 NM_004860 /// XR_243572 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 35436_at L06147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L06147:Human (clone SY11) golgin-95 mRNA, complete cds /cds=(18,1880) /gb=L06147 /gi=306781 /ug=Hs.169055 /len=2067 L06147 golgin A2 GOLGA2 2801 NM_004486 /// XM_005251930 /// XM_005251931 /// XM_005251932 0000278 // mitotic cell cycle // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 35617_at U29725 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U29725:Human BMK1 alpha kinase mRNA, complete cds /cds=(221,2671) /gb=U29725 /gi=973306 /ug=Hs.3080 /len=2980 U29725 mitogen-activated protein kinase 7 MAPK7 5598 NM_002749 /// NM_139032 /// NM_139033 /// NM_139034 /// XM_005256719 /// XM_006721557 /// XM_006721558 /// XM_006721559 /// XM_006721560 0000165 // MAPK cascade // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030821 // negative regulation of cAMP catabolic process // non-traceable author statement /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from genetic interaction /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // traceable author statement /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from electronic annotation /// 0060761 // negative regulation of response to cytokine stimulus // inferred from genetic interaction /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from genetic interaction /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 0071499 // cellular response to laminar fluid shear stress // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction 35626_at U30894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U30894:Human N-sulphoglucosamine sulphohydrolase mRNA, complete cds /cds=(12,1520) /gb=U30894 /gi=1173542 /ug=Hs.31074 /len=2657 U30894 N-sulfoglucosamine sulfohydrolase SGSH 6448 NM_000199 /// XM_005257582 /// XM_005257583 /// XR_429917 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006029 // proteoglycan metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016250 // N-sulfoglucosamine sulfohydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 35666_at U38276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U38276:Human semaphorin III family homolog mRNA, complete cds /cds=(315,2576) /gb=U38276 /gi=1061350 /ug=Hs.32981 /len=3534 U38276 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F SEMA3F 6405 NM_004186 /// XM_005265381 /// XM_005265382 /// XM_006713289 /// XM_006713290 0001755 // neural crest cell migration // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045499 // chemorepellent activity // inferred from direct assay 35671_at U02619 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U02619:Human TFIIIC Box B-binding subunit mRNA, complete cds /cds=(60,6389) /gb=U02619 /gi=414932 /ug=Hs.331 /len=6996 U02619 general transcription factor IIIC, polypeptide 1, alpha 220kDa GTF3C1 2975 NM_001286242 /// NM_001520 /// XM_006721042 0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 35685_at AL031228 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z14000:H.sapiens RING1 gene /cds=(75,1208) /gb=Z14000 /gi=296063 /ug=Hs.35384 /len=1529 AL031228 ring finger protein 1 RING1 6015 NM_002931 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016568 // chromatin modification // non-traceable author statement /// 0016574 // histone ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 35776_at AF064243 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF064243:Homo sapiens intersectin short form mRNA, complete cds /cds=(106,3768) /gb=AF064243 /gi=3859852 /ug=Hs.66392 /len=5272 AF064243 intersectin 1 (SH3 domain protein) ITSN1 6453 NM_001001132 /// NM_003024 /// XM_005261026 /// XM_005261027 /// XM_005261031 /// XR_244289 0006897 // endocytosis // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 35820_at M76477 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X62078:H.sapiens mRNA for GM2 activator protein /cds=UNKNOWN /gb=X62078 /gi=313158 /ug=Hs.69743 /len=2436 M76477 GM2 ganglioside activator GM2A 2760 NM_000405 /// NM_001167607 0001573 // ganglioside metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019377 // glycolipid catabolic process // non-traceable author statement /// 0019915 // lipid storage // inferred from electronic annotation /// 0030149 // sphingolipid catabolic process // non-traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050877 // neurological system process // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051345 // positive regulation of hydrolase activity // inferred from electronic annotation 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045179 // apical cortex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016004 // phospholipase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030290 // sphingolipid activator protein activity // non-traceable author statement 35846_at M24899 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M24899:Human triiodothyronine (ear7) mRNA, complete cds /cds=(411,1883) /gb=M24899 /gi=537521 /ug=Hs.724 /len=2309 M24899 thyroid hormone receptor, alpha THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 35974_at U10485 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U10485:Human lymphoid-restricted membrane protein (Jaw1) mRNA, complete cds /cds=(574,2241) /gb=U10485 /gi=505685 /ug=Hs.40202 /len=2417 U10485 lymphoid-restricted membrane protein LRMP 4033 NM_001204126 /// NM_001204127 /// NM_006152 /// XM_005253370 /// XM_005253371 /// XM_005253372 /// XM_005253374 /// XM_006719075 /// XM_006719076 /// XM_006719077 /// XR_242890 /// XR_429033 0002376 // immune system process // inferred from electronic annotation /// 0006903 // vesicle targeting // traceable author statement /// 0006906 // vesicle fusion // traceable author statement /// 0007338 // single fertilization // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 36004_at AF074382 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF074382:Homo sapiens IkB kinase gamma subunit (IKK-gamma) mRNA, complete cds /cds=(148,1407) /gb=AF074382 /gi=3641279 /ug=Hs.43505 /len=1976 AF074382 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma IKBKG 8517 NM_001099856 /// NM_001099857 /// NM_001145255 /// NM_003639 /// XM_005274760 /// XM_005274761 /// XM_005274763 /// XM_005274764 /// XM_006724853 0000187 // activation of MAPK activity // traceable author statement /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007254 // JNK cascade // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // non-traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008385 // IkappaB kinase complex // inferred from direct assay /// 0008385 // IkappaB kinase complex // traceable author statement 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 36019_at L26260 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L26260:Human MHC class III HLA-RP gene, complete cds /cds=(128,1222) /gb=L26260 /gi=452070 /ug=Hs.444 /len=1620 L26260 serine/threonine kinase 19 STK19 8859 NM_004197 /// NM_032454 /// NR_026717 0006468 // protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 36030_at AL080214 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL080214:Homo sapiens mRNA; cDNA DKFZp586I2223 (from clone DKFZp586I2223) /cds=(0,318) /gb=AL080214 /gi=5262704 /ug=Hs.46659 /len=1272 AL080214 intermediate filament family orphan 1 IFFO1 25900 NM_001039670 /// NM_001193457 /// NM_001193459 /// NM_015438 /// NM_080730 /// NM_080731 /// NR_036467 /// XM_006718973 /// XM_006718974 /// XM_006718975 /// XM_006718976 /// XM_006718977 /// XM_006718978 /// XM_006718979 /// XM_006718980 /// XM_006718981 /// XM_006718982 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 36084_at D38548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D38548:Human mRNA for KIAA0076 gene, complete cds /cds=(86,5182) /gb=D38548 /gi=559706 /ug=Hs.51039 /len=5253 D38548 cullin 7 CUL7 9820 NM_001168370 /// NM_014780 /// XM_005249503 /// XM_006715285 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001890 // placenta development // inferred from direct assay /// 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from genetic interaction /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005680 // anaphase-promoting complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 1990393 // 3M complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 36129_at AB007857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB007857:Homo sapiens KIAA0397 mRNA, complete cds /cds=(54,1520) /gb=AB007857 /gi=2662074 /ug=Hs.7416 /len=6629 AB007857 small G protein signaling modulator 2 SGSM2 9905 NM_001098509 /// NM_014853 /// XM_006721613 /// XM_006721614 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation 36475_at Z97630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z97630:Human DNA sequence from clone 466N1 on chromosome 22q12-13 Contains H1F0(H1 histone family, member 0) gene, 2-amino-3-ketobutyrate -CoA ligase( nuclear gene encoding mitochondrial protein), GALR3 (galanin receptor) gene, ESTs, GSSs and CpG islands /cds=(3,1262) /gb=Z97630 /gi=4582128 /ug=Hs.54609 /len=1442 Z97630 glycine C-acetyltransferase GCAT 23464 NM_001171690 /// NM_014291 /// XM_005261409 /// XM_005261410 /// XM_005261411 /// XM_006724172 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019518 // L-threonine catabolic process to glycine // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008890 // glycine C-acetyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 36499_at D87469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D87469:Human mRNA for KIAA0279 gene, partial cds /cds=(0,7226) /gb=D87469 /gi=1665820 /ug=Hs.57652 /len=8924 D87469 cadherin, EGF LAG seven-pass G-type receptor 2 CELSR2 1952 NM_001408 /// XM_005270580 /// XM_006710405 0001764 // neuron migration // inferred from electronic annotation /// 0003341 // cilium movement // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from sequence or structural similarity /// 0021591 // ventricular system development // inferred from electronic annotation /// 0021999 // neural plate anterior/posterior regionalization // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033326 // cerebrospinal fluid secretion // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 36545_s_at AB011114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB011114:Homo sapiens mRNA for KIAA0542 protein, complete cds /cds=(393,3299) /gb=AB011114 /gi=3043607 /ug=Hs.62209 /len=5280 AB011114 Sfi1 homolog, spindle assembly associated (yeast) SFI1 9814 NM_001007467 /// NM_001258325 /// NM_001258326 /// NM_001258327 /// NM_014775 /// XM_005261868 /// XM_005261869 /// XM_005261870 /// XM_005261871 /// XM_005261872 /// XM_005261873 /// XM_005261874 /// XM_006724388 /// XM_006724389 /// XM_006724390 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 36552_at AL080220 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL080220:Homo sapiens mRNA; cDNA DKFZp586P0123 (from clone DKFZp586P0123) /cds=(0,1067) /gb=AL080220 /gi=5262711 /ug=Hs.6285 /len=1732 AL080220 C2 calcium-dependent domain containing 3 C2CD3 26005 NM_001286577 /// NM_015531 /// XM_005273893 /// XM_005273895 /// XM_005273896 /// XM_005273897 /// XM_006718495 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0021997 // neural plate axis specification // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030162 // regulation of proteolysis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0035058 // nonmotile primary cilium assembly // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 36553_at AA669799 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA669799:ag36c04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1118886 /clone_end=3' /gb=AA669799 /gi=2631298 /ug=Hs.6315 /len=679 AA669799 acetylserotonin O-methyltransferase-like ASMTL 8623 NM_001173473 /// NM_001173474 /// NM_004192 /// XM_005274434 /// XM_005274783 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 36554_at Y15521 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Y15521:Homo sapiens ASMTL gene /cds=(0,1889) /gb=Y15521 /gi=3808147 /ug=Hs.6315 /len=1890 Y15521 acetylserotonin O-methyltransferase-like ASMTL 8623 NM_001173473 /// NM_001173474 /// NM_004192 /// XM_005274434 /// XM_005274783 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 36564_at W27419 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W27419:31a10 Homo sapiens cDNA /gb=W27419 /gi=1307241 /ug=Hs.64239 /len=803 W27419 ring finger protein 19B RNF19B 127544 NM_001127361 /// NM_153341 /// XM_005270460 /// XM_006710356 /// XM_006710357 /// XM_006710358 0002376 // immune system process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042267 // natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0072643 // interferon-gamma secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 36566_at AJ222967 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AJ222967:Homo sapiens mRNA for cystinosin /cds=(339,1442) /gb=AJ222967 /gi=3036839 /ug=Hs.64837 /len=2611 AJ222967 cystinosin, lysosomal cystine transporter CTNS 1497 NM_001031681 /// NM_004937 /// XM_005256485 /// XM_006721463 /// XM_006721464 0006520 // cellular amino acid metabolic process // non-traceable author statement /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0007616 // long-term memory // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015811 // L-cystine transport // inferred from direct assay /// 0015811 // L-cystine transport // inferred from mutant phenotype /// 0015811 // L-cystine transport // non-traceable author statement /// 0046034 // ATP metabolic process // inferred from mutant phenotype /// 0048058 // compound eye corneal lens development // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // non-traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015184 // L-cystine transmembrane transporter activity // inferred from mutant phenotype /// 0015184 // L-cystine transmembrane transporter activity // non-traceable author statement 36612_at D87470 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D87470:Human mRNA for KIAA0280 gene, partial cds /cds=(0,876) /gb=D87470 /gi=1665822 /ug=Hs.75400 /len=6837 D87470 family with sequence similarity 168, member A FAM168A 23201 NM_001286050 /// NM_001286051 /// NM_015159 /// XM_005273852 /// XM_006718482 36711_at AL021977 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL021977:bK447C4.1 (novel MAFF (v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein F) LIKE protein) /cds=(0,494) /gb=AL021977 /gi=4914526 /ug=Hs.51305 /len=2128 AL021977 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F MAFF 23764 NM_001161572 /// NM_001161573 /// NM_001161574 /// NM_012323 /// NM_152878 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007567 // parturition // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045604 // regulation of epidermal cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 36742_at U34249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U34249:Human putative zinc finger protein (ZNFB7) mRNA, complete cds /cds=(493,1890) /gb=U34249 /gi=4096653 /ug=Hs.59015 /len=2236 U34249 tripartite motif containing 15 TRIM15 89870 NM_033229 /// NM_052812 /// XM_005249471 /// XM_005272907 /// XM_005274898 /// XM_005275063 /// XM_005275195 /// XM_005275319 /// XM_005275490 /// XM_005275628 0007500 // mesodermal cell fate determination // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 1900246 // positive regulation of RIG-I signaling pathway // inferred from mutant phenotype /// 1901253 // negative regulation of intracellular transport of viral material // inferred from mutant phenotype /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 36829_at AF022991 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF022991:Homo sapiens Rigui (RIGUI) mRNA, complete cds /cds=(187,4059) /gb=AF022991 /gi=2435506 /ug=Hs.68398 /len=4656 AF022991 microRNA 6883 /// period circadian clock 1 MIR6883 /// PER1 5187 /// 102465532 NM_002616 /// NR_106943 /// XM_005256689 /// XM_005256690 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from expression pattern /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // traceable author statement /// 0010608 // posttranscriptional regulation of gene expression // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity /// 1900015 // regulation of cytokine production involved in inflammatory response // inferred from sequence or structural similarity /// 1900744 // regulation of p38MAPK cascade // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from sequence or structural similarity /// 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay 36830_at U80034 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U80034:Human mitochondrial intermediate peptidase precursor (MIPEP) mRNA, mitochondrial gene encoding mitochondrial protein, complete cds /cds=(74,2215) /gb=U80034 /gi=1763641 /ug=Hs.68583 /len=2374 U80034 mitochondrial intermediate peptidase MIPEP 4285 NM_005932 0006508 // proteolysis // inferred from electronic annotation /// 0006627 // protein processing involved in protein targeting to mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 36865_at AB018302 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB018302:Homo sapiens mRNA for KIAA0759 protein, partial cds /cds=(0,2022) /gb=AB018302 /gi=3882238 /ug=Hs.7285 /len=4006 AB018302 angel homolog 1 (Drosophila) ANGEL1 23357 NM_015305 /// XR_429300 /// XR_429301 /// XR_429302 36888_at AB020648 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB020648:Homo sapiens mRNA for KIAA0841 protein, partial cds /cds=(0,1925) /gb=AB020648 /gi=4240170 /ug=Hs.7426 /len=4283 AB020648 HAUS augmin-like complex, subunit 5 HAUS5 23354 NM_015302 /// XM_006723119 /// XR_243915 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0070652 // HAUS complex // inferred from direct assay 36907_at M88468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M88468:Homo sapiens mevalonate kinase mRNA, complete cds /cds=(91,1281) /gb=M88468 /gi=307197 /ug=Hs.75138 /len=1967 M88468 mevalonate kinase MVK 4598 NM_000431 /// NM_001114185 /// XM_005253883 /// XM_005253884 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004496 // mevalonate kinase activity // inferred from direct assay /// 0004496 // mevalonate kinase activity // inferred from mutant phenotype /// 0004496 // mevalonate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 36920_at U46024 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U46024:Homo sapiens myotubularin (MTM1) mRNA, complete cds /cds=(54,1865) /gb=U46024 /gi=1378039 /ug=Hs.75302 /len=3411 U46024 myotubularin 1 MTM1 4534 NM_000252 /// XM_005274687 /// XM_006724820 /// XM_006724821 /// XM_006724822 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044088 // regulation of vacuole organization // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045109 // intermediate filament organization // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0048311 // mitochondrion distribution // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from direct assay 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031674 // I band // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0052629 // phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity // inferred from direct assay 36936_at U58766 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U58766:Human FX protein mRNA, complete cds /cds=(74,1039) /gb=U58766 /gi=1381178 /ug=Hs.75801 /len=1330 U58766 tissue specific transplantation antigen P35B TSTA3 7264 NM_003313 /// XM_005251050 /// XM_005251051 /// XM_005251052 /// XM_006725093 /// XM_006725094 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019673 // GDP-mannose metabolic process // inferred from direct assay /// 0019835 // cytolysis // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from direct assay /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042356 // GDP-4-dehydro-D-rhamnose reductase activity // traceable author statement /// 0050577 // GDP-L-fucose synthase activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 36994_at M62762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M62762:Human vacuolar H+ ATPase proton channel subunit mRNA, complete cds /cds=(230,697) /gb=M62762 /gi=189675 /ug=Hs.76159 /len=1162 M62762 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c ATP6V0C 527 NM_001198569 /// NM_001694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 37004_at J02761 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. J02761:Human pulmonary surfactant-associated protein B (SP-B) mRNA, complete cds /cds=(13,1158) /gb=J02761 /gi=190673 /ug=Hs.76305 /len=1996 J02761 surfactant protein B SFTPB 6439 NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation 37005_at D28124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D28124:Human mRNA for unknown product, complete cds /cds=(61,603) /gb=D28124 /gi=641821 /ug=Hs.76307 /len=1929 D28124 MINOS1-NBL1 readthrough /// neuroblastoma 1, DAN family BMP antagonist MINOS1-NBL1 /// NBL1 4681 /// 100532736 NM_001204084 /// NM_001204085 /// NM_001204086 /// NM_001204088 /// NM_001204089 /// NM_001278164 /// NM_001278165 /// NM_001278166 /// NM_005380 /// NM_182744 0007399 // nervous system development // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0038098 // sequestering of BMP from receptor via BMP binding // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048263 // determination of dorsal identity // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005739 // mitochondrion // /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016015 // morphogen activity // inferred from sequence or structural similarity /// 0036122 // BMP binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 37012_at U03271 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U03271:Human F-actin capping protein beta subunit mRNA, complete cds /cds=(0,818) /gb=U03271 /gi=595256 /ug=Hs.76368 /len=1077 U03271 capping protein (actin filament) muscle Z-line, beta CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 37020_at X56692 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X56692:H.sapiens mRNA for C-reactive protein /cds=(89,763) /gb=X56692 /gi=30212 /ug=Hs.76452 /len=1645 X56692 C-reactive protein, pentraxin-related CRP 1401 NM_000567 0001666 // response to hypoxia // inferred from electronic annotation /// 0006953 // acute-phase response // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008228 // opsonization // traceable author statement /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010888 // negative regulation of lipid storage // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001849 // complement component C1q binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0033265 // choline binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046790 // virion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 37022_at U41344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U41344:Human prolargin (PRELP) gene, 5 flanking sequence and /cds=(16,1164) /gb=U41344 /gi=3123824 /ug=Hs.76494 /len=1801 U41344 proline/arginine-rich end leucine-rich repeat protein PRELP 5549 NM_002725 /// NM_201348 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 37028_at U83981 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U83981:Homo sapiens apoptosis associated protein (GADD34) mRNA, complete cds /cds=(222,2246) /gb=U83981 /gi=3258617 /ug=Hs.76556 /len=2331 U83981 protein phosphatase 1, regulatory subunit 15A PPP1R15A 23645 NM_014330 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 37079_at U82319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U82319:Homo sapiens clone YDD19 mRNA sequence /cds=(0,206) /gb=U82319 /gi=1938350 /ug=Hs.97193 /len=1005 U82319 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 NUS1P3 11049 0001525 // angiogenesis // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from electronic annotation /// 0032367 // intracellular cholesterol transport // inferred from genetic interaction /// 0055092 // sterol homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016765 // transferase activity, transferring alkyl or aryl (other than methyl) groups // inferred from electronic annotation 37117_at Z83838 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z83838:Human DNA sequence from PAC 127B20 on chromosome 22q11.2-qter, contains gene for GTPase-activating protein similar to rhoGAP protein. ribosomal protein L6 pseudogene, ESTs and CA repeat /cds=(0,926) /gb=Z83838 /gi=2276307 /ug=Hs.102336 /len=927 Z83838 Rho GTPase activating protein 8 /// PRR5-ARHGAP8 readthrough ARHGAP8 /// PRR5-ARHGAP8 23779 /// 553158 NM_001017526 /// NM_001198726 /// NM_181334 /// NM_181335 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031932 // TORC2 complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 37145_at M85276 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M85276:Homo sapiens NKG5 gene, complete cds /cds=(128,565) /gb=M85276 /gi=189229 /ug=Hs.105806 /len=738 M85276 granulysin GNLY 10578 NM_006433 /// NM_012483 /// XM_005264084 /// XM_005264085 /// XM_005264086 /// XM_005264087 0006968 // cellular defense response // traceable author statement /// 0031640 // killing of cells of other organism // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 37152_at L07592 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L07592:Human peroxisome proliferator activated receptor mRNA, complete cds /cds=(337,1662) /gb=L07592 /gi=190229 /ug=Hs.106415 /len=3301 L07592 peroxisome proliferator-activated receptor delta PPARD 5467 NM_001171818 /// NM_001171819 /// NM_001171820 /// NM_006238 /// NM_177435 /// XM_005249193 /// XM_005249194 /// XM_006715120 /// XM_006715121 /// XM_006715122 /// XM_006715123 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // inferred from sequence or structural similarity /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006776 // vitamin A metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008366 // axon ensheathment // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // traceable author statement /// 0009299 // mRNA transcription // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0015758 // glucose transport // non-traceable author statement /// 0015908 // fatty acid transport // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032966 // negative regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // non-traceable author statement /// 0045684 // positive regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046697 // decidualization // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0051546 // keratinocyte migration // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005504 // fatty acid binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation /// 0070539 // linoleic acid binding // inferred from direct assay 37170_at AB015331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB015331:Homo sapiens HRIHFB2017 mRNA, partial cds /cds=(0,650) /gb=AB015331 /gi=3970851 /ug=Hs.108903 /len=1064 AB015331 BMP2 inducible kinase BMP2K 55589 NM_017593 /// NM_198892 /// XM_005263117 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from physical interaction /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // inferred from electronic annotation 37201_at D38535 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D38535:Human mRNA for PK-120 /cds=(129,2921) /gb=D38535 /gi=624879 /ug=Hs.76415 /len=3058 D38535 inter-alpha-trypsin inhibitor heavy chain family, member 4 ITIH4 3700 NM_001166449 /// NM_002218 0006953 // acute-phase response // inferred from expression pattern /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030212 // hyaluronan metabolic process // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 37226_at U15172 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U15172:Homo sapiens BCL2/adenovirus E1B 19kD-interacting protein 1 (BNIP1) mRNA, complete cds /cds=(10,696) /gb=U15172 /gi=558841 /ug=Hs.77572 /len=1100 U15172 BCL2/adenovirus E1B 19kDa interacting protein 1 BNIP1 662 NM_001205 /// NM_013978 /// NM_013979 /// NM_013980 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from physical interaction /// 0007029 // endoplasmic reticulum organization // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016320 // endoplasmic reticulum membrane fusion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred by curator 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 37232_at AB011158 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB011158:Homo sapiens mRNA for KIAA0586 protein, complete cds /cds=(274,4875) /gb=AB011158 /gi=3043695 /ug=Hs.77724 /len=5064 AB011158 KIAA0586 KIAA0586 9786 NM_001244189 /// NM_001244190 /// NM_001244191 /// NM_001244192 /// NM_001244193 /// NM_014749 /// XM_006720336 /// XM_006720337 /// XM_006720338 /// XM_006720339 /// XM_006720340 /// XM_006720341 /// XM_006720342 /// XM_006720343 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0070201 // regulation of establishment of protein localization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from direct assay 37254_at U09366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U09366:Human zinc finger protein ZNF133 /cds=(445,2409) /gb=U09366 /gi=487782 /ug=Hs.78434 /len=2643 U09366 zinc finger protein 133 ZNF133 7692 NM_001083330 /// NM_001282995 /// NM_001282996 /// NM_001282997 /// NM_001282998 /// NM_001282999 /// NM_001283000 /// NM_001283001 /// NM_001283002 /// NM_001283003 /// NM_001283004 /// NM_001283005 /// NM_001283006 /// NM_001283007 /// NM_001283008 /// NM_003434 /// XM_005260818 /// XM_005260819 /// XM_005260820 /// XM_005260823 /// XM_006723616 /// XM_006723617 /// XM_006723618 /// XM_006723619 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 37278_at X92762 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X92762:H.sapiens mRNA for tafazzins protein /cds=(288,1166) /gb=X92762 /gi=1263131 /ug=Hs.79021 /len=1883 X92762 tafazzin TAZ 6901 NM_000116 /// NM_181311 /// NM_181312 /// NM_181313 /// NM_181314 /// NR_024048 /// XM_006724836 /// XM_006724837 /// XM_006724838 /// XM_006724839 /// XM_006724840 /// XM_006724841 /// XM_006724842 0006644 // phospholipid metabolic process // traceable author statement /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042407 // cristae formation // inferred from mutant phenotype /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from direct assay 37384_at D86995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D13640:Human mRNA for KIAA0015 gene, complete cds /cds=(106,1470) /gb=D13640 /gi=286006 /ug=Hs.77961 /len=5134 D86995 protein phosphatase, Mg2+/Mn2+ dependent, 1F PPM1F 9647 NM_014634 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010811 // positive regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045927 // positive regulation of growth // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 37408_at AB014609 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014609:Homo sapiens mRNA for KIAA0709 protein, complete cds /cds=(116,4555) /gb=AB014609 /gi=3327231 /ug=Hs.7835 /len=5641 AB014609 mannose receptor, C type 2 MRC2 9902 NM_006039 0001649 // osteoblast differentiation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from direct assay 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation 37424_at AB029343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB029343:Homo sapiens HCR (a-helix coiled-coil rod homologue) gene, complete cds /cds=(22,2292) /gb=AB029343 /gi=5360900 /ug=Hs.110746 /len=2445 AB029343 coiled-coil alpha-helical rod protein 1 CCHCR1 54535 NM_001105563 /// NM_001105564 /// NM_019052 /// XM_005272832 /// XM_005272833 /// XM_005272835 /// XM_005272836 /// XM_005272839 /// XM_005272840 /// XM_005274987 /// XM_005274988 /// XM_005274990 /// XM_005274991 /// XM_005274994 /// XM_005274995 /// XM_005275137 /// XM_005275140 /// XM_005275265 /// XM_005275269 /// XM_005275422 /// XM_005275423 /// XM_006715119 /// XM_006725488 /// XM_006725702 /// XM_006725819 /// XM_006725911 /// XM_006726003 /// XM_006726004 0006611 // protein export from nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 37425_g_at AB029343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB029343:Homo sapiens HCR (a-helix coiled-coil rod homologue) gene, complete cds /cds=(22,2292) /gb=AB029343 /gi=5360900 /ug=Hs.110746 /len=2445 AB029343 coiled-coil alpha-helical rod protein 1 CCHCR1 54535 NM_001105563 /// NM_001105564 /// NM_019052 /// XM_005272832 /// XM_005272833 /// XM_005272835 /// XM_005272836 /// XM_005272839 /// XM_005272840 /// XM_005274987 /// XM_005274988 /// XM_005274990 /// XM_005274991 /// XM_005274994 /// XM_005274995 /// XM_005275137 /// XM_005275140 /// XM_005275265 /// XM_005275269 /// XM_005275422 /// XM_005275423 /// XM_006715119 /// XM_006725488 /// XM_006725702 /// XM_006725819 /// XM_006725911 /// XM_006726003 /// XM_006726004 0006611 // protein export from nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 37433_at AF077954 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF077954:Homo sapiens protein inhibitor of activated STAT protein PIASx-beta mRNA, complete cds /cds=(0,1865) /gb=AF077954 /gi=3643114 /ug=Hs.111323 /len=1866 AF077954 protein inhibitor of activated STAT, 2 PIAS2 9063 NM_004671 /// NM_173206 /// XM_005258377 /// XM_005258379 /// XM_005258381 /// XM_005258382 /// XM_005258383 /// XM_006722571 /// XM_006722572 /// XM_006722573 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 37462_i_at L21990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L21990:Human spliceosomal protein (SAP 62) gene, complete cds /cds=(0,1394) /gb=L21990 /gi=409218 /ug=Hs.115232 /len=1395 L21990 splicing factor 3a, subunit 2, 66kDa SF3A2 8175 NM_007165 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 37512_at U89281 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U89281:Human oxidative 3 alpha hydroxysteroid dehydrogenase mRNA, complete cds /cds=(105,1058) /gb=U89281 /gi=2661210 /ug=Hs.11958 /len=1506 U89281 hydroxysteroid (17-beta) dehydrogenase 6 HSD17B6 8630 NM_003725 /// XM_005269207 /// XM_005269208 /// XM_005269209 /// XM_006719672 /// XR_245961 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // non-traceable author statement /// 0006710 // androgen catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // traceable author statement /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation 37547_at U85995 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U85995:Human clone IMAGE-22181 unknown protein mRNA, partial cds /cds=(0,1291) /gb=U85995 /gi=1835749 /ug=Hs.79340 /len=1696 U85995 Bardet-Biedl syndrome 9 BBS9 27241 NM_001033604 /// NM_001033605 /// NM_014451 /// NM_198428 /// XM_005249700 /// XM_005249701 /// XM_006715687 /// XM_006715688 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 37549_g_at U87408 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U87408:Human clone IMAGE-74593 unknown protein mRNA, partial cds /cds=(0,1362) /gb=U87408 /gi=1842104 /ug=Hs.79340 /len=1982 U87408 Bardet-Biedl syndrome 9 BBS9 27241 NM_001033604 /// NM_001033605 /// NM_014451 /// NM_198428 /// XM_005249700 /// XM_005249701 /// XM_006715687 /// XM_006715688 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034464 // BBSome // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 37566_at AB028968 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB028968:Homo sapiens mRNA for KIAA1045 protein, partial cds /cds=(0,1284) /gb=AB028968 /gi=5689426 /ug=Hs.7989 /len=5712 AB028968 KIAA1045 KIAA1045 23349 NM_015297 /// XM_005251420 /// XR_242502 0046872 // metal ion binding // inferred from electronic annotation 37577_at U79256 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U79256:Human clone 23719 mRNA sequence /cds=UNKNOWN /gb=U79256 /gi=1710209 /ug=Hs.80305 /len=1196 U79256 Rho GTPase activating protein 19 ARHGAP19 84986 NM_001204300 /// NM_001256423 /// NM_032900 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 37586_at D87073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D87073:Human mRNA for KIAA0236 gene, complete cds /cds=(436,5499) /gb=D87073 /gi=1510146 /ug=Hs.80526 /len=5878 D87073 zinc finger protein 142 ZNF142 7701 NM_001105537 /// NM_005081 /// NR_073599 /// NR_073600 /// XM_006712730 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 37590_g_at AL109698 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL109698:Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 26539 /cds=UNKNOWN /gb=AL109698 /gi=5689808 /ug=Hs.8065 /len=2035 AL109698 Homo sapiens cDNA FLJ31419 fis, clone NT2NE2000356. /// AK055981 /// RP11-617F23.1 37652_at AB002328 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002328:Human mRNA for KIAA0330 gene, partial cds /cds=(0,5710) /gb=AB002328 /gi=2224600 /ug=Hs.7840 /len=6143 AB002328 calcineurin binding protein 1 CABIN1 23523 NM_001199281 /// NM_001201429 /// NM_012295 /// XM_005261415 /// XM_005261416 /// XM_005261417 /// XM_005261419 /// XM_005261420 /// XM_006724179 /// XM_006724180 /// XM_006724181 /// XM_006724182 /// XM_006724183 /// XM_006724184 /// XR_430404 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 37793_r_at AF034956 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF034956:Homo sapiens RAD51D mRNA, complete cds /cds=(124,993) /gb=AF034956 /gi=2920581 /ug=Hs.125244 /len=1564 AF034956 RAD51 paralog D RAD51D 5892 NM_001142571 /// NM_002878 /// NM_133627 /// NM_133628 /// NM_133629 /// NM_133630 /// NR_037711 /// NR_037712 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0042148 // strand invasion // inferred from direct assay 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005657 // replication fork // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0033063 // Rad51B-Rad51C-Rad51D-XRCC2 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043015 // gamma-tubulin binding // inferred from direct assay 37796_at AF053356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF053356:Homo sapiens chromosome 7q22 sequence /cds=(0,2498) /gb=AF053356 /gi=3135305 /ug=Hs.125742 /len=2836 AF053356 leucine-rich repeats and calponin homology (CH) domain containing 4 /// Sin3A-associated protein, 25kDa LRCH4 /// SAP25 4034 /// 100316904 NM_001168682 /// NM_001289934 /// NM_002319 /// XM_005250096 /// XM_005250346 /// XM_005250347 /// XM_006715822 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 37802_r_at AL049226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL049226:Homo sapiens mRNA; cDNA DKFZp564M0916 (from clone DKFZp564M0916) /cds=UNKNOWN /gb=AL049226 /gi=4499955 /ug=Hs.126541 /len=1402 AL049226 family with sequence similarity 63, member B FAM63B 54629 NM_001040450 /// NM_001040453 /// NM_019092 37831_at AB011117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB011117:Homo sapiens mRNA for KIAA0545 protein, partial cds /cds=(0,3390) /gb=AB011117 /gi=3043613 /ug=Hs.129943 /len=5520 AB011117 signal-induced proliferation-associated 1 like 3 SIPA1L3 23094 NM_015073 /// XM_005258671 /// XM_005258672 /// XM_006723112 /// XR_430194 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 37860_at AL049942 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL049942:Homo sapiens mRNA; cDNA DKFZp564F1422 (from clone DKFZp564F1422) /cds=(0,1491) /gb=AL049942 /gi=4884185 /ug=Hs.139240 /len=2308 AL049942 zinc finger protein 337 ZNF337 26152 NM_001290261 /// NM_015655 /// XM_005260702 /// XM_006723558 /// XM_006723559 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 37872_at AF072468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF072468:Homo sapiens (JH8) mRNA, partial cds /cds=(0,1251) /gb=AF072468 /gi=3435202 /ug=Hs.142296 /len=1700 AF072468 Jrk homolog (mouse) JRK 8629 NM_001077527 /// NM_001279352 /// NM_003724 /// XM_006716677 /// XM_006716678 /// XM_006716679 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 37892_at J04177 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. J04177:Human alpha-1 type XI collagen (COL11A1) mRNA, complete cds /cds=(161,5581) /gb=J04177 /gi=179729 /ug=Hs.82772 /len=6158 J04177 collagen, type XI, alpha 1 COL11A1 1301 NM_001190709 /// NM_001854 /// NM_080629 /// NM_080630 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0035989 // tendon development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // inferred from direct assay /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // non-traceable author statement 37943_at AB002319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002319:Human mRNA for KIAA0321 gene, partial cds /cds=(0,4628) /gb=AB002319 /gi=2224582 /ug=Hs.8663 /len=6540 AB002319 zinc finger, FYVE domain containing 26 ZFYVE26 23503 NM_015346 /// XM_006720093 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 37950_at X74496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X74496:H.sapiens mRNA for prolyl oligopeptidase /cds=(0,2132) /gb=X74496 /gi=558595 /ug=Hs.86978 /len=2562 X74496 prolyl endopeptidase PREP 5550 NM_002726 /// XM_005267044 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 37953_s_at U78181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U78181:Human sodium channel 2 (hBNaC2) mRNA, complete cds /cds=(229,1815) /gb=U78181 /gi=1871169 /ug=Hs.87220 /len=3785 U78181 acid-sensing (proton-gated) ion channel 1 ASIC1 41 NM_001095 /// NM_001256830 /// NM_020039 /// NR_046389 /// XM_006719397 0001101 // response to acid // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // non-traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009268 // response to pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0050915 // sensory perception of sour taste // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0070207 // protein homotrimerization // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071467 // cellular response to pH // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005261 // cation channel activity // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // traceable author statement /// 0022839 // ion gated channel activity // inferred from electronic annotation /// 0044736 // acid-sensing ion channel activity // inferred from direct assay /// 0044736 // acid-sensing ion channel activity // inferred from sequence or structural similarity 37965_at AA181053 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA181053:zp66g11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-625220 /clone_end=3' /gb=AA181053 /gi=1764536 /ug=Hs.8836 /len=626 AA181053 parvin, beta PARVB 29780 NM_001003828 /// NM_001243385 /// NM_001243386 /// NM_013327 /// XM_005261593 /// XM_005261594 /// XM_005261595 /// XM_005261596 /// XM_006724236 0007155 // cell adhesion // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0071963 // establishment or maintenance of cell polarity regulating cell shape // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 37966_at AA187563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA187563:zp66g11.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-625220 /clone_end=5' /gb=AA187563 /gi=1773781 /ug=Hs.8836 /len=531 AA187563 parvin, beta PARVB 29780 NM_001003828 /// NM_001243385 /// NM_001243386 /// NM_013327 /// XM_005261593 /// XM_005261594 /// XM_005261595 /// XM_005261596 /// XM_006724236 0007155 // cell adhesion // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from mutant phenotype /// 0030032 // lamellipodium assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0071963 // establishment or maintenance of cell polarity regulating cell shape // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 37986_at M60459 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M60459:Human erythropoietin receptor mRNA, complete cds /cds=(105,1631) /gb=M60459 /gi=182244 /ug=Hs.89548 /len=1818 M60459 erythropoietin receptor EPOR 2057 NM_000121 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 37996_s_at L08835 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L08835:Homo sapiens DMR-N9, partial cds; and myotonic dystrophy kinase (DM kinase) gene, complete cds /cds=(776,2665) /gb=L08835 /gi=181601 /ug=Hs.898 /len=3407 L08835 dystrophia myotonica-protein kinase DMPK 1760 NM_001081560 /// NM_001081562 /// NM_001081563 /// NM_001288764 /// NM_001288765 /// NM_001288766 /// NM_004409 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from mutant phenotype /// 0008016 // regulation of heart contraction // inferred from direct assay /// 0010657 // muscle cell apoptotic process // inferred from direct assay /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0014722 // regulation of skeletal muscle contraction by calcium ion signaling // inferred from electronic annotation /// 0014853 // regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0051823 // regulation of synapse structural plasticity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017020 // myosin phosphatase regulator activity // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 38037_at M60278 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M60278:Human heparin-binding EGF-like growth factor mRNA, complete cds /cds=(261,887) /gb=M60278 /gi=183866 /ug=Hs.799 /len=2342 M60278 heparin-binding EGF-like growth factor HBEGF 1839 NM_001945 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051545 // negative regulation of elastin biosynthetic process // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype 38043_at X55448 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X55448:H.sapiens G6PD gene for glucose-6-phosphate dehydrogenase /cds=(277,969) /gb=X55448 /gi=450527 /ug=Hs.80206 /len=1606 X55448 family with sequence similarity 3, member A FAM3A 60343 NM_001171132 /// NM_001171133 /// NM_001171134 /// NM_001282311 /// NM_001282312 /// NM_021806 /// XM_005274714 /// XM_005274716 /// XM_005277879 /// XM_006724831 /// XM_006724832 /// XM_006724833 /// XM_006724834 0005576 // extracellular region // inferred from electronic annotation 38069_at Z67743 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z67743:H.sapiens mRNA for CLC-7 chloride channel protein /cds=(0,2369) /gb=Z67743 /gi=1177439 /ug=Hs.80768 /len=2393 Z67743 chloride channel, voltage-sensitive 7 CLCN7 1186 NM_001114331 /// NM_001287 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 38149_at D29642 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D29642:Human mRNA for KIAA0053 gene, complete cds /cds=(193,2109) /gb=D29642 /gi=473934 /ug=Hs.1528 /len=2739 D29642 Rho GTPase activating protein 25 ARHGAP25 9938 NM_001007231 /// NM_001166276 /// NM_001166277 /// NM_014882 /// XM_005264675 /// XM_005264676 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 38157_at AF059252 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF059252:Homo sapiens clone 1 HLA class III protein Dom3z (DOM3Z) mRNA, complete cds /cds=(129,1319) /gb=AF059252 /gi=3372629 /ug=Hs.153299 /len=1386 AF059252 decapping exoribonuclease DXO 1797 NM_005510 /// XM_006715005 /// XM_006715006 /// XM_006715007 /// XM_006725474 /// XM_006725475 /// XM_006725476 /// XM_006725688 /// XM_006725689 /// XM_006725690 /// XM_006725898 /// XM_006725899 /// XM_006725900 /// XM_006725985 /// XM_006725986 /// XM_006725987 /// XM_006726078 /// XM_006726079 /// XM_006726080 /// XR_427826 /// XR_430856 /// XR_430934 /// XR_430935 /// XR_430996 /// XR_431013 /// XR_431043 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0050779 // RNA destabilization // inferred from sequence or structural similarity /// 0071028 // nuclear mRNA surveillance // inferred from sequence or structural similarity /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from sequence or structural similarity /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0008409 // 5'-3' exonuclease activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034353 // RNA pyrophosphohydrolase activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 38158_at D79987 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D79987:Human mRNA for KIAA0165 gene, complete cds /cds=(1113,6500) /gb=D79987 /gi=1136391 /ug=Hs.153479 /len=6662 D79987 extra spindle pole bodies homolog 1 (S. cerevisiae) ESPL1 9700 NM_012291 /// XM_006719705 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0000212 // meiotic spindle organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007127 // meiosis I // inferred from electronic annotation /// 0040001 // establishment of mitotic spindle localization // non-traceable author statement /// 0045143 // homologous chromosome segregation // inferred from electronic annotation /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // non-traceable author statement /// 0045875 // negative regulation of sister chromatid cohesion // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // non-traceable author statement /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 38241_at U90548 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U90548:Human butyrophilin (BTF3) mRNA, complete cds /cds=(171,1925) /gb=U90548 /gi=2062697 /ug=Hs.167741 /len=2926 U90548 butyrophilin, subfamily 3, member A3 BTN3A3 10384 NM_001242803 /// NM_006994 /// NM_197974 0002376 // immune system process // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from mutant phenotype 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 38269_at AL050147 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL050147:Homo sapiens mRNA; cDNA DKFZp586E0820 (from clone DKFZp586E0820) /cds=(0,1630) /gb=AL050147 /gi=4884153 /ug=Hs.91146 /len=1837 AL050147 protein kinase D2 PRKD2 25865 NM_001079880 /// NM_001079881 /// NM_001079882 /// NM_016457 /// XM_005258716 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from genetic interaction /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0032793 // positive regulation of CREB transcription factor activity // inferred from genetic interaction /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from genetic interaction /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from genetic interaction /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from genetic interaction /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from genetic interaction /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from genetic interaction /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0061154 // endothelial tube morphogenesis // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1901727 // positive regulation of histone deacetylase activity // inferred from genetic interaction /// 1902533 // positive regulation of intracellular signal transduction // inferred from mutant phenotype /// 2000573 // positive regulation of DNA biosynthetic process // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 38290_at AF037195 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF037195:Homo sapiens regulator of G protein signaling RGS14 mRNA, complete cds /cds=(73,1398) /gb=AF037195 /gi=2708809 /ug=Hs.9347 /len=1531 AF037195 regulator of G-protein signaling 14 RGS14 10636 NM_006480 /// XM_005265794 /// XM_005265795 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from sequence or structural similarity /// 0031914 // negative regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from sequence or structural similarity /// 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation 38340_at AB014555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014555:Homo sapiens mRNA for KIAA0655 protein, partial cds /cds=(0,3253) /gb=AB014555 /gi=3327123 /ug=Hs.96731 /len=4457 AB014555 huntingtin interacting protein 1 related HIP1R 9026 NM_003959 /// XM_005253627 /// XM_005253628 /// XM_006719683 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 38398_at AB002356 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002356:Human mRNA for KIAA0358 gene, complete cds /cds=(187,4932) /gb=AB002356 /gi=2224656 /ug=Hs.82548 /len=5942 AB002356 MAP-kinase activating death domain MADD 8567 NM_001135943 /// NM_001135944 /// NM_003682 /// NM_130470 /// NM_130471 /// NM_130472 /// NM_130473 /// NM_130474 /// NM_130475 /// NM_130476 /// XM_005253188 /// XM_005253189 /// XM_005253190 /// XM_005253191 /// XM_005253192 /// XM_005253193 /// XM_005253194 /// XM_005253195 /// XM_005253196 /// XM_005253197 /// XM_005253198 /// XM_005253199 /// XM_005253200 /// XM_005253201 /// XM_005253202 /// XM_005253203 /// XM_005253204 /// XM_005253205 /// XM_005253206 /// XM_006718360 /// XM_006718361 /// XM_006718362 /// XM_006718363 /// XR_242830 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032483 // regulation of Rab protein signal transduction // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0030295 // protein kinase activator activity // traceable author statement 38447_at U08438 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U08438:Human beta-adrenergic receptor kinase (ADRBK1) gene /cds=(40,2109) /gb=U08438 /gi=2182231 /ug=Hs.83636 /len=3550 U08438 adrenergic, beta, receptor kinase 1 ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from sequence or structural similarity /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 38487_at D87433 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D87433:Human mRNA for KIAA0246 gene, partial cds /cds=(0,6639) /gb=D87433 /gi=1665760 /ug=Hs.84753 /len=6777 D87433 stabilin 1 STAB1 23166 NM_015136 /// XM_005264973 /// XM_005264974 /// XM_005264975 /// XM_006713065 /// XM_006713066 /// XR_427261 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from direct assay /// 0055114 // oxidation-reduction process // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // non-traceable author statement /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay 38521_at X59350 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X59350:H.sapiens mRNA for B cell membrane protein CD22 /cds=(56,2599) /gb=X59350 /gi=36090 /ug=Hs.171763 /len=3250 X59350 CD22 molecule CD22 933 NM_001185099 /// NM_001185100 /// NM_001185101 /// NM_001278417 /// NM_001771 /// NM_024916 0007155 // cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 38671_at AB014520 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014520:Homo sapiens mRNA for KIAA0620 protein, partial cds /cds=(0,5957) /gb=AB014520 /gi=3327053 /ug=Hs.105958 /len=6754 AB014520 plexin D1 PLXND1 23129 NM_015103 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from physical interaction 38691_s_at J03553 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. J03553:Human pulmonary surfactant protein (SP5) mRNA, complete cds /cds=(146,739) /gb=J03553 /gi=338306 /ug=Hs.1074 /len=963 J03553 surfactant protein C SFTPC 6440 NM_001172357 /// NM_001172410 /// NM_003018 /// XM_005273598 /// XM_006716379 /// XM_006716380 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070741 // response to interleukin-6 // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071732 // cellular response to nitric oxide // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 38703_at AF005050 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF005050:Homo sapiens aspartyl aminopeptidase mRNA, complete cds /cds=(170,1588) /gb=AF005050 /gi=4101588 /ug=Hs.108117 /len=1694 AF005050 aspartyl aminopeptidase DNPEP 23549 NM_012100 /// XM_005246430 /// XM_005246431 /// XM_005246432 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 38707_r_at S75174 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. S75174:E2F-4=transcription factor [human, Nalm6 and HeLa cells, mRNA, 1539 nt] /cds=(54,1304) /gb=S75174 /gi=802120 /ug=Hs.108371 /len=1539 S75174 E2F transcription factor 4, p107/p130-binding E2F4 1874 NM_001950 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008015 // blood circulation // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 38710_at AL096714 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL096714:Homo sapiens mRNA; cDNA DKFZp564E242 (from clone DKFZp564E242) /cds=UNKNOWN /gb=AL096714 /gi=5419847 /ug=Hs.108504 /len=1904 AL096714 uncharacterized LOC101927673 /// OTU deubiquitinase, ubiquitin aldehyde binding 1 LOC101927673 /// OTUB1 55611 /// 101927673 NM_017670 /// NR_003089 /// XR_247234 /// XR_247664 /// XR_252904 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from direct assay /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 38766_at AB002307 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002307:Human mRNA for KIAA0309 gene, partial cds /cds=(0,5007) /gb=AB002307 /gi=2224558 /ug=Hs.87908 /len=6648 AB002307 uncharacterized LOC100862671 /// Snf2-related CREBBP activator protein LOC100862671 /// SRCAP 10847 /// 100862671 NM_001256829 /// NM_006662 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 38892_at D87077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D87077:Human mRNA for KIAA0240 gene, partial cds /cds=(0,2953) /gb=D87077 /gi=1510154 /ug=Hs.196275 /len=6060 D87077 GLTSCR1-like GLTSCR1L 23506 NM_015349 /// XM_005248972 /// XM_005248973 38918_at AF083105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF083105:Homo sapiens HMG box factor SOX-13 mRNA, complete cds /cds=(111,2783) /gb=AF083105 /gi=3982828 /ug=Hs.201671 /len=3583 AF083105 SRY (sex determining region Y)-box 13 SOX13 9580 NM_005686 /// XM_005245623 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 38964_r_at U12707 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U12707:Human Wiskott-Aldrich syndrome protein (WASP) mRNA, complete cds /cds=(34,1542) /gb=U12707 /gi=695150 /ug=Hs.2157 /len=1806 U12707 Wiskott-Aldrich syndrome WAS 7454 NM_000377 0006461 // protein complex assembly // traceable author statement /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016197 // endosomal transport // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 39248_at N74607 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N74607:za55a01.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-296424 /clone_end=3' /gb=N74607 /gi=1231892 /ug=Hs.234642 /len=487 N74607 aquaporin 3 (Gill blood group) AQP3 360 NM_004925 0002684 // positive regulation of immune system process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015793 // glycerol transport // inferred from electronic annotation /// 0015840 // urea transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0033280 // response to vitamin D // traceable author statement /// 0042476 // odontogenesis // inferred from expression pattern /// 0045616 // regulation of keratinocyte differentiation // traceable author statement /// 0051592 // response to calcium ion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // traceable author statement /// 0015254 // glycerol channel activity // inferred from direct assay 39249_at AB001325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB001325:Human AQP3 gene for aquaporine 3 (water channel), partail cds /cds=(60,938) /gb=AB001325 /gi=1854373 /ug=Hs.234642 /len=1442 AB001325 aquaporin 3 (Gill blood group) AQP3 360 NM_004925 0002684 // positive regulation of immune system process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015793 // glycerol transport // inferred from electronic annotation /// 0015840 // urea transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0033280 // response to vitamin D // traceable author statement /// 0042476 // odontogenesis // inferred from expression pattern /// 0045616 // regulation of keratinocyte differentiation // traceable author statement /// 0051592 // response to calcium ion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // traceable author statement /// 0015254 // glycerol channel activity // inferred from direct assay 39313_at AB002342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002342:Human mRNA for KIAA0344 gene, complete cds /cds=(618,4358) /gb=AB002342 /gi=2280478 /ug=Hs.239895 /len=5787 AB002342 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay 39318_at X82240 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X82240:H.sapiens mRNA for Tcell leukemia/lymphoma 1 /cds=(45,389) /gb=X82240 /gi=624960 /ug=Hs.2484 /len=1312 X82240 T-cell leukemia/lymphoma 1A TCL1A 8115 NM_001098725 /// NM_021966 /// NR_049726 0007275 // multicellular organismal development // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 39402_at M15330 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M15330:Human interleukin 1-beta (IL1B) mRNA, complete cds /cds=(86,895) /gb=M15330 /gi=186283 /ug=Hs.126256 /len=1497 M15330 interleukin 1, beta IL1B 3553 NM_000576 /// XM_006712496 0000165 // MAPK cascade // inferred from mutant phenotype /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001660 // fever generation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // non-traceable author statement /// 0002711 // positive regulation of T cell mediated immunity // inferred by curator /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from sequence or structural similarity /// 0014805 // smooth muscle adaptation // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0030213 // hyaluronan biosynthetic process // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030730 // sequestering of triglyceride // inferred from direct assay /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0031622 // positive regulation of fever generation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032308 // positive regulation of prostaglandin secretion // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032611 // interleukin-1 beta production // inferred from electronic annotation /// 0032725 // positive regulation of granulocyte macrophage colony-stimulating factor production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // traceable author statement /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0033129 // positive regulation of histone phosphorylation // non-traceable author statement /// 0033198 // response to ATP // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034116 // positive regulation of heterotypic cell-cell adhesion // non-traceable author statement /// 0035066 // positive regulation of histone acetylation // non-traceable author statement /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0035505 // positive regulation of myosin light chain kinase activity // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042221 // response to chemical // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0045080 // positive regulation of chemokine biosynthetic process // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from mutant phenotype /// 0045410 // positive regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045833 // negative regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // non-traceable author statement /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0050996 // positive regulation of lipid catabolic process // inferred from sequence or structural similarity /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060355 // positive regulation of cell adhesion molecule production // non-traceable author statement /// 0060559 // positive regulation of calcidiol 1-monooxygenase activity // inferred from direct assay /// 0070164 // negative regulation of adiponectin secretion // inferred from sequence or structural similarity /// 0070487 // monocyte aggregation // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071639 // positive regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from mutant phenotype /// 0005149 // interleukin-1 receptor binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction 39548_at U77970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U77970:Human neuronal PAS2 (NPAS2) mRNA, complete cds /cds=(286,2760) /gb=U77970 /gi=1840059 /ug=Hs.106705 /len=2880 U77970 neuronal PAS domain protein 2 NPAS2 4862 NM_002518 /// XM_005263953 /// XM_005263954 /// XM_005263955 /// XM_005263957 /// XM_005263958 /// XM_005263959 /// XM_005263960 /// XM_005263961 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from physical interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 39549_at AI743090 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI743090:wg87a11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2372060 /clone_end=3' /gb=AI743090 /gi=5111378 /ug=Hs.106705 /len=547 AI743090 neuronal PAS domain protein 2 NPAS2 4862 NM_002518 /// XM_005263953 /// XM_005263954 /// XM_005263955 /// XM_005263957 /// XM_005263958 /// XM_005263959 /// XM_005263960 /// XM_005263961 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042745 // circadian sleep/wake cycle // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051775 // response to redox state // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from physical interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 39582_at AL050166 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL050166:Homo sapiens mRNA; cDNA DKFZp586D1122 (from clone DKFZp586D1122) /cds=UNKNOWN /gb=AL050166 /gi=4884381 /ug=Hs.26295 /len=2654 AL050166 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 39650_s_at AB007895 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB007895:Homo sapiens KIAA0435 mRNA, complete cds /cds=(1195,3528) /gb=AB007895 /gi=2662150 /ug=Hs.31438 /len=5347 AB007895 pecanex-like 2 (Drosophila) PCNXL2 80003 NM_014801 /// NM_024938 /// XM_005273272 /// XM_006711816 /// XR_247042 /// XR_426918 /// XR_426919 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation 396_f_at X97671 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database X97671 /FEATURE=cds /DEFINITION=HSERYTHR H.sapiens mRNA for erythropoietin receptor X97671 erythropoietin receptor EPOR 2057 NM_000121 /// NR_033663 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0038162 // erythropoietin-mediated signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004900 // erythropoietin receptor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 39705_at AB014600 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB014600:Homo sapiens mRNA for KIAA0700 protein, partial cds /cds=(0,3393) /gb=AB014600 /gi=3327213 /ug=Hs.13999 /len=5020 AB014600 SIN3 transcription regulator family member B SIN3B 23309 NM_015260 /// XM_005259832 /// XM_006722704 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030849 // autosome // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 39729_at L19185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L19185:Human natural killer cell enhancing factor (NKEFB) mRNA, complete cds /cds=(124,720) /gb=L19185 /gi=440307 /ug=Hs.146354 /len=980 L19185 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181737 /// NM_181738 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 39763_at M36803 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M36803:Human hemopexin gene /cds=(28,1416) /gb=M36803 /gi=497766 /ug=Hs.1504 /len=1576 M36803 hemopexin HPX 3263 NM_000613 /// XM_005252883 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0015886 // heme transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0060332 // positive regulation of response to interferon-gamma // inferred from electronic annotation /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015232 // heme transporter activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 39817_s_at AF040105 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF040105:Homo sapiens RCL (Rcl) mRNA, complete cds /cds=(17,541) /gb=AF040105 /gi=2773296 /ug=Hs.109752 /len=644 AF040105 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 DNPH1 10591 NM_006443 /// NM_199184 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009159 // deoxyribonucleoside monophosphate catabolic process // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050144 // nucleoside deoxyribosyltransferase activity // inferred from electronic annotation /// 0070694 // deoxyribonucleoside 5'-monophosphate N-glycosidase activity // inferred from sequence or structural similarity 39835_at U93181 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U93181:Homo sapiens nuclear dual-specificity phosphatase (SBF1) mRNA, partial cds /cds=(0,5095) /gb=U93181 /gi=3015537 /ug=Hs.112049 /len=5228 U93181 SET binding factor 1 SBF1 6305 NM_002972 /// XM_005261931 /// XM_005261932 /// XM_005261934 /// XM_005261935 0006470 // protein dephosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // traceable author statement /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 39854_r_at AF055000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF055000:Homo sapiens clone 24519 unknown mRNA, partial cds /cds=(0,1235) /gb=AF055000 /gi=3005716 /ug=Hs.118463 /len=1590 AF055000 patatin-like phospholipase domain containing 2 PNPLA2 57104 NM_020376 /// XM_003403858 /// XM_006718265 /// XM_006718266 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010891 // negative regulation of sequestering of triglyceride // inferred from direct assay /// 0010898 // positive regulation of triglyceride catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from electronic annotation /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 39891_at AI246730 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI246730:qk40b01.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1871401 /clone_end=3' /gb=AI246730 /gi=3842127 /ug=Hs.126901 /len=770 AI246730 zinc finger protein 710 ZNF710 374655 NM_198526 /// XM_005254905 /// XM_005254906 /// XM_005254907 /// XM_006720498 /// XM_006720499 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 39966_at AF059274 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF059274:Homo sapiens neuroglycan C mRNA, complete cds /cds=(6,1625) /gb=AF059274 /gi=3820499 /ug=Hs.45127 /len=1728 AF059274 chondroitin sulfate proteoglycan 5 (neuroglycan C) CSPG5 10675 NM_001206942 /// NM_001206943 /// NM_001206944 /// NM_001206945 /// NM_006574 0005975 // carbohydrate metabolic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0031103 // axon regeneration // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030660 // Golgi-associated vesicle membrane // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement 40016_g_at AB002301 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002301:Human mRNA for KIAA0303 gene, partial cds /cds=(0,6415) /gb=AB002301 /gi=2224546 /ug=Hs.54985 /len=6629 AB002301 microtubule associated serine/threonine kinase family member 4 MAST4 375449 NM_001164664 /// NM_001290226 /// NM_001290227 /// NM_001290228 /// NM_015183 /// NM_198828 /// XM_005248498 /// XM_006714602 /// XM_006714603 /// XM_006714604 /// XM_006714605 /// XM_006714606 /// XM_006714607 /// XM_006714608 /// XM_006714609 /// XM_006714610 /// XM_006714611 /// XM_006714612 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 40020_at AB011536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB011536:Homo sapiens mRNA for MEGF2, partial cds /cds=(0,4095) /gb=AB011536 /gi=3449297 /ug=Hs.55173 /len=5832 AB011536 cadherin, EGF LAG seven-pass G-type receptor 3 CELSR3 1951 NM_001407 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0008272 // sulfate transport // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // inferred from electronic annotation 40093_at X83425 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X83425:H.sapiens LU gene for Lutheran blood group glycoprotein /cds=(22,1908) /gb=X83425 /gi=603559 /ug=Hs.155048 /len=2402 X83425 basal cell adhesion molecule (Lutheran blood group) BCAM 4059 NM_001013257 /// NM_005581 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005055 // laminin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from mutant phenotype 40148_at U62325 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U62325:Human FE65-like protein (hFE65L) mRNA, partial cds /cds=(0,2194) /gb=U62325 /gi=1657751 /ug=Hs.15740 /len=2896 U62325 amyloid beta (A4) precursor protein-binding, family B, member 2 APBB2 323 NM_001166050 /// NM_001166051 /// NM_001166052 /// NM_001166053 /// NM_001166054 /// NM_004307 /// NM_173075 /// XM_005248101 /// XM_006714005 /// XM_006714006 /// XM_006714007 /// XM_006714008 /// XM_006714009 /// XM_006714010 /// XM_006714011 /// XM_006714012 0001764 // neuron migration // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007411 // axon guidance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0001540 // beta-amyloid binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity 40149_at AL049924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL049924:Homo sapiens mRNA; cDNA DKFZp547G1110 (from clone DKFZp547G1110) /cds=(0,1623) /gb=AL049924 /gi=4884170 /ug=Hs.15744 /len=2381 AL049924 SH2B adaptor protein 1 SH2B1 25970 NM_001145795 /// NM_001145796 /// NM_001145797 /// NM_001145812 /// NM_015503 /// XM_005255240 /// XM_006721031 /// XM_006721032 /// XM_006721033 /// XM_006721034 /// XM_006721035 /// XM_006721036 /// XM_006721037 0006928 // cellular component movement // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from electronic annotation /// 2000278 // regulation of DNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 40189_at M93651 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M93651:Human set gene, complete cds /cds=(3,836) /gb=M93651 /gi=338038 /ug=Hs.145279 /len=2562 M93651 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 40225_at D88435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D88435:Homo sapiens mRNA for HsGAK, complete cds /cds=(0,3935) /gb=D88435 /gi=2506079 /ug=Hs.153227 /len=4331 D88435 cyclin G associated kinase GAK 2580 NM_001286833 /// NM_005255 /// XM_005272268 /// XM_005272269 /// XM_005272270 /// XM_005272272 /// XM_005272273 /// XM_006713874 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 40255_at AC004531 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AC004531:Homo sapiens Chromosome 16 BAC clone CIT987SK-A-67A1 /cds=(0,1622) /gb=AC004531 /gi=3337392 /ug=Hs.155049 /len=1623 AC004531 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 40273_at AA485440 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA485440:zx90g03.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-811060 /clone_end=3' /gb=AA485440 /gi=2214659 /ug=Hs.155402 /len=547 AA485440 sphingosine kinase 2 SPHK2 56848 NM_001204158 /// NM_001204159 /// NM_001204160 /// NM_001243876 /// NM_020126 /// XM_006723290 /// XM_006723291 /// XM_006723292 /// XM_006723293 /// XM_006723294 0001568 // blood vessel development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006669 // sphinganine-1-phosphate biosynthetic process // non-traceable author statement /// 0006670 // sphingosine metabolic process // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046834 // lipid phosphorylation // inferred from electronic annotation /// 0046834 // lipid phosphorylation // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008481 // sphinganine kinase activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // non-traceable author statement /// 0017050 // D-erythro-sphingosine kinase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 40284_at AB028021 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB028021:Homo sapiens HNF-3beta mRNA for hepatocyte nuclear factor-3 beta, complete cds /cds=(196,1569) /gb=AB028021 /gi=4958949 /ug=Hs.155651 /len=1944 AB028021 forkhead box A2 FOXA2 3170 NM_021784 /// NM_153675 /// XM_006723562 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0000433 // negative regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // not recorded /// 0001705 // ectoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0010817 // regulation of hormone levels // not recorded /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0021533 // cell differentiation in hindbrain // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from direct assay /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0033132 // negative regulation of glucokinase activity // inferred from sequence or structural similarity /// 0040019 // positive regulation of embryonic development // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // not recorded /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // not recorded /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048646 // anatomical structure formation involved in morphogenesis // inferred from electronic annotation /// 0048665 // neuron fate specification // not recorded /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061448 // connective tissue development // inferred from electronic annotation /// 0070741 // response to interleukin-6 // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from sequence or structural similarity /// 2000049 // positive regulation of cell-cell adhesion mediated by cadherin // inferred by curator /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2000971 // negative regulation of detection of glucose // inferred from sequence or structural similarity /// 2000976 // regulation of transcription from RNA polymerase II promoter involved in detection of glucose // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype 40359_at M91083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M91083:Human DNA-binding protein (HRC1) mRNA, complete cds /cds=UNKNOWN /gb=M91083 /gi=184389 /ug=Hs.72925 /len=1539 M91083 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 RASSF7 8045 NM_001143993 /// NM_001143994 /// NM_003475 /// XM_005253147 /// XM_005253148 /// XM_005253149 /// XM_005253150 /// XM_005253151 /// XM_006718337 /// XM_006718338 /// XM_006725142 /// XM_006725143 /// XM_006725144 /// XM_006725145 /// XM_006725146 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement 40420_at AB015718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB015718:Homo sapiens lok mRNA for protein kinase, complete cds /cds=(50,2956) /gb=AB015718 /gi=4001687 /ug=Hs.16134 /len=4221 AB015718 serine/threonine kinase 10 STK10 6793 NM_005990 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0071593 // lymphocyte aggregation // inferred from electronic annotation /// 2000401 // regulation of lymphocyte migration // inferred from mutant phenotype 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042801 // polo kinase kinase activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 40446_at AL021366 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL021366:cICK0721Q.4.1 (PHD finger protein 2) (isoform 2) /cds=(215,1918) /gb=AL021366 /gi=3169115 /ug=Hs.166204 /len=2260 AL021366 PHD finger protein 1 PHF1 5252 NM_002636 /// NM_024165 /// NR_027692 /// XM_006715109 /// XM_006715110 /// XM_006715111 /// XM_006726097 /// XM_006726098 /// XM_006726099 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 40465_at AF026402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF026402:Homo sapiens U5 snRNP 100 kD protein mRNA, complete cds /cds=(39,2501) /gb=AF026402 /gi=2655201 /ug=Hs.168103 /len=3215 AF026402 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 DDX23 9416 NM_004818 /// XM_006719699 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 40472_at AF007155 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF007155:Homo sapiens clone 23763 unknown mRNA, partial cds /cds=(0,314) /gb=AF007155 /gi=2852635 /ug=Hs.168694 /len=1369 AF007155 lysophosphatidylcholine acyltransferase 4 LPCAT4 254531 NM_153613 /// XM_006720454 /// XR_243087 /// XR_243088 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // inferred from mutant phenotype /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047166 // 1-alkenylglycerophosphoethanolamine O-acyltransferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047192 // 1-alkylglycerophosphocholine O-acetyltransferase activity // inferred from electronic annotation /// 0071617 // lysophospholipid acyltransferase activity // inferred from direct assay /// 0071617 // lysophospholipid acyltransferase activity // inferred from mutant phenotype 40489_at D31840 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D31840:Human DRPLA mRNA for ORF, complete cds /cds=(238,3795) /gb=D31840 /gi=862329 /ug=Hs.169488 /len=4279 D31840 atrophin 1 ATN1 1822 NM_001007026 /// NM_001940 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030011 // maintenance of cell polarity // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0050827 // toxin receptor binding // inferred from electronic annotation 40524_at X79510 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X79510:H.sapiens mRNA for protein-tyrosine-phosphatase D1 /cds=(332,3856) /gb=X79510 /gi=532055 /ug=Hs.155693 /len=4080 X79510 protein tyrosine phosphatase, non-receptor type 21 PTPN21 11099 NM_007039 /// XM_005267287 /// XM_006720011 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 40560_at U28049 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U28049:Human TBX2 (TXB2) mRNA, complete cds /cds=(47,2155) /gb=U28049 /gi=924927 /ug=Hs.168357 /len=2279 U28049 T-box 2 TBX2 6909 NM_005994 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003256 // regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007521 // muscle cell fate determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036302 // atrioventricular canal development // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048596 // embryonic camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048738 // cardiac muscle tissue development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060465 // pharynx development // inferred from sequence or structural similarity /// 0060560 // developmental growth involved in morphogenesis // inferred from electronic annotation /// 0060596 // mammary placode formation // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from direct assay /// 1901208 // negative regulation of heart looping // inferred from sequence or structural similarity /// 1901211 // negative regulation of cardiac chamber formation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay 40562_at AF011499 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M69013:Human guanine nucleotide-binding regulatory protein (G-y-alpha) mRNA, complete cds /cds=(186,1265) /gb=M69013 /gi=183690 /ug=Hs.1686 /len=1540 AF011499 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 40569_at M58297 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M58297:Human zinc finger protein 42 (MZF-1) mRNA, complete cds /cds=(1090,2547) /gb=M58297 /gi=189043 /ug=Hs.169832 /len=2678 M58297 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 40612_at AB029040 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB029040:Homo sapiens mRNA for KIAA1117 protein, partial cds /cds=(0,4135) /gb=AB029040 /gi=5689570 /ug=Hs.173637 /len=4440 AB029040 dopey family member 1 DOPEY1 23033 NM_001199942 /// NM_015018 /// XM_006715393 /// XM_006715394 /// XM_006715395 /// XM_006715396 /// XM_006715397 /// XM_006715398 /// XM_006715399 /// XM_006715400 /// XM_006715401 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation 40640_at U62317 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U62317:Chromosome 22q13 BAC Clone CIT987SK-384D8 complete sequence /cds=(0,1601) /gb=U62317 /gi=1399959 /ug=Hs.180903 /len=2223 U62317 non-SMC condensin II complex, subunit H2 NCAPH2 29781 NM_001185011 /// NM_014551 /// NM_152299 /// XM_005261912 0000278 // mitotic cell cycle // traceable author statement /// 0001654 // eye development // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003012 // muscle system process // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0055070 // copper ion homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from direct assay 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 40665_at M83772 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M83772:Human flavin-containing monooxygenase form II (FMO2) mRNA, complete cds /cds=(136,1737) /gb=M83772 /gi=188630 /ug=Hs.80876 /len=2106 M83772 flavin containing monooxygenase 3 FMO3 2328 NM_001002294 /// NM_006894 /// XM_005245044 0006805 // xenobiotic metabolic process // traceable author statement /// 0017144 // drug metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004499 // N,N-dimethylaniline monooxygenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0034899 // trimethylamine monooxygenase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 40687_at M96789 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M96789:Homo sapiens connexin 37 (GJA4) mRNA, complete cds /cds=(64,1065) /gb=M96789 /gi=183222 /ug=Hs.83468 /len=1591 M96789 gap junction protein, alpha 4, 37kDa GJA4 2701 NM_002060 /// XM_005270750 0001568 // blood vessel development // inferred from electronic annotation /// 0003158 // endothelium development // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005921 // gap junction // traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 40829_at AB028960 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB028960:Homo sapiens mRNA for KIAA1037 protein, partial cds /cds=(0,1467) /gb=AB028960 /gi=5689410 /ug=Hs.172825 /len=5091 AB028960 WD and tetratricopeptide repeats 1 WDTC1 23038 NM_001276252 /// NM_015023 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0055082 // cellular chemical homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation 40837_at M99436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. M99436:Human transducin-like enhancer protein (TLE2) mRNA, complete cds /cds=(25,2256) /gb=M99436 /gi=307511 /ug=Hs.173063 /len=2271 M99436 transducin-like enhancer of split 2 TLE2 7089 NM_001144761 /// NM_001144762 /// NM_003260 /// XM_005259636 /// XM_005259637 /// XM_006722864 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 40850_at L37033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L37033:Human FK-506 binding protein homologue (FKBP38) mRNA, complete cds /cds=(140,1207) /gb=L37033 /gi=965469 /ug=Hs.173464 /len=1613 L37033 FK506 binding protein 8, 38kDa FKBP8 23770 NM_012181 /// XM_005259841 /// XM_005259842 /// XM_005259844 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0001708 // cell fate specification // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030510 // regulation of BMP signaling pathway // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005740 // mitochondrial envelope // /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 41037_at U63824 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U63824:Human transcription factor RTEF-1 (RTEF1) mRNA, complete cds /cds=(163,1467) /gb=U63824 /gi=1561727 /ug=Hs.94865 /len=1670 U63824 TEA domain family member 4 TEAD4 7004 NM_003213 /// NM_201441 /// NM_201443 0001501 // skeletal system development // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0001830 // trophectodermal cell fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0035329 // hippo signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 41047_at AI885170 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI885170:wl90e10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2432202 /clone_end=3' /gb=AI885170 /gi=5590334 /ug=Hs.95867 /len=564 AI885170 chromosome 9 open reading frame 16 C9orf16 79095 NM_024112 41113_at AI871396 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI871396:wl81f07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2431333 /clone_end=3' /gb=AI871396 /gi=5545445 /ug=Hs.101414 /len=521 AI871396 zinc finger protein 500 ZNF500 26048 NM_021646 /// XM_005255243 /// XM_005255244 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 41160_at AC005943 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AC005943:Homo sapiens chromosome 19, cosmid R30538 /cds=(22,897) /gb=AC005943 /gi=3850563 /ug=Hs.178728 /len=2559 AC005943 methyl-CpG binding domain protein 3 MBD3 53615 NM_001281453 /// NM_001281454 /// NM_003926 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016581 // NuRD complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay 41220_at AB023208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB023208:Homo sapiens mRNA for KIAA0991 protein, complete cds /cds=(732,2000) /gb=AB023208 /gi=4589625 /ug=Hs.181002 /len=3938 AB023208 septin 9 SEPT9 10801 NM_001113491 /// NM_001113492 /// NM_001113493 /// NM_001113494 /// NM_001113495 /// NM_001113496 /// NM_001293695 /// NM_001293696 /// NM_001293697 /// NM_001293698 /// NM_006640 /// XM_005256959 /// XM_005256960 /// XM_005256961 /// XM_005256962 /// XM_006721643 /// XM_006721644 0006184 // GTP catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 41329_at AI458463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI458463:tj99b02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2149611 /clone_end=3' /gb=AI458463 /gi=4311042 /ug=Hs.24243 /len=594 AI458463 SCY1-like 3 (S. cerevisiae) SCYL3 57147 NM_020423 /// NM_181093 /// XM_006711465 /// XM_006711466 /// XM_006711467 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0004672 // protein kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 41386_i_at AB002344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002344:Human mRNA for KIAA0346 gene, partial cds /cds=(0,4852) /gb=AB002344 /gi=2280479 /ug=Hs.103915 /len=6121 AB002344 lysine (K)-specific demethylase 6B KDM6B 23135 NM_001080424 /// XM_005256549 /// XM_005256550 /// XM_005256551 /// XM_005256552 /// XM_005256554 /// XM_006721483 /// XM_006721484 0006954 // inflammatory response // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // not recorded 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // not recorded 41387_r_at AB002344 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB002344:Human mRNA for KIAA0346 gene, partial cds /cds=(0,4852) /gb=AB002344 /gi=2280479 /ug=Hs.103915 /len=6121 AB002344 lysine (K)-specific demethylase 6B KDM6B 23135 NM_001080424 /// XM_005256549 /// XM_005256550 /// XM_005256551 /// XM_005256552 /// XM_005256554 /// XM_006721483 /// XM_006721484 0006954 // inflammatory response // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from sequence or structural similarity /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // not recorded 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // not recorded 41397_at AF070588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF070588:Homo sapiens clone 24554 unknown mRNA /cds=(376,1488) /gb=AF070588 /gi=3387961 /ug=Hs.104788 /len=1821 AF070588 zinc finger protein 821 ZNF821 55565 NM_001201552 /// NM_001201553 /// NM_001201554 /// NM_001201556 /// NM_017530 /// XM_005256033 /// XM_005256035 /// XM_006721233 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 41469_at L10343 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. L10343:Huma elafin gene, complete cds /cds=(516,869) /gb=L10343 /gi=190337 /ug=Hs.112341 /len=871 L10343 peptidase inhibitor 3, skin-derived PI3 5266 NM_002638 0007620 // copulation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 41512_at AL042733 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL042733:DKFZp434B2222_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434B2222 /clone_end=3' /gb=AL042733 /gi=5422182 /ug=Hs.30982 /len=782 AL042733 BRCA1 associated protein BRAP 8315 NM_006768 /// XM_005253944 0000165 // MAPK cascade // inferred from direct assay /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 41553_at AI738702 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI738702:wi22b11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2390973 /clone_end=3' /gb=AI738702 /gi=5100683 /ug=Hs.40539 /len=650 AI738702 oxidative stress induced growth inhibitor family member 2 OSGIN2 734 NM_001126111 /// NM_004337 0007126 // meiotic nuclear division // inferred from electronic annotation 41577_at AB020630 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB020630:Homo sapiens mRNA for KIAA0823 protein, partial cds /cds=(0,1239) /gb=AB020630 /gi=4240131 /ug=Hs.45719 /len=5597 AB020630 protein phosphatase 1, regulatory subunit 16B PPP1R16B 26051 NM_001172735 /// NM_015568 0007165 // signal transduction // non-traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // non-traceable author statement 41644_at AB018333 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AB018333:Homo sapiens mRNA for KIAA0790 protein, partial cds /cds=(0,3961) /gb=AB018333 /gi=3882300 /ug=Hs.12002 /len=4469 AB018333 SAM and SH3 domain containing 1 SASH1 23328 NM_015278 /// XM_005266874 /// XM_005266875 /// XM_006715406 0000209 // protein polyubiquitination // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0031666 // positive regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 1900044 // regulation of protein K63-linked ubiquitination // inferred from direct assay /// 1900745 // positive regulation of p38MAPK cascade // inferred from mutant phenotype /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from mutant phenotype /// 1902498 // regulation of protein autoubiquitination // inferred from direct assay 0043234 // protein complex // inferred from mutant phenotype 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from direct assay 41657_at AF035625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AF035625:Homo sapiens serine threonine kinase 11 (STK11) mRNA, complete cds /cds=(338,1639) /gb=AF035625 /gi=2754826 /ug=Hs.122755 /len=2158 AF035625 serine/threonine kinase 11 STK11 6794 NM_000455 /// XM_005259617 /// XM_005259618 0001558 // regulation of cell growth // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010212 // response to ionizing radiation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0036399 // TCR signalosome assembly // inferred from electronic annotation /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043276 // anoikis // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0036398 // TCR signalosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 41660_at AL031588 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL031588:dJ1163J1.1 (ortholog of mouse transmembrane receptor Celsr1 (KIAA0279 LIKE EGF-like domain containing protein similar to rat MEG /cds=(0,4433) /gb=AL031588 /gi=4007108 /ug=Hs.123043 /len=6438 AL031588 cadherin, EGF LAG seven-pass G-type receptor 1 CELSR1 9620 NM_014246 /// XM_006724383 0001736 // establishment of planar polarity // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // non-traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042249 // establishment of planar polarity of embryonic epithelium // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0045176 // apical protein localization // inferred from electronic annotation /// 0048105 // establishment of body hair planar orientation // inferred from electronic annotation /// 0060488 // orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060489 // planar dichotomous subdivision of terminal units involved in lung branching morphogenesis // inferred from electronic annotation /// 0060490 // lateral sprouting involved in lung morphogenesis // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090251 // protein localization involved in establishment of planar polarity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // non-traceable author statement 41856_at AL049370 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL049370:Homo sapiens mRNA; cDNA DKFZp586D0918 (from clone DKFZp586D0918) /cds=UNKNOWN /gb=AL049370 /gi=4500162 /ug=Hs.13350 /len=2705 AL049370 unc-5 homolog B (C. elegans) UNC5B 219699 NM_001244889 /// NM_170744 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0033564 // anterior/posterior axon guidance // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 41858_at AL049261 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL049261:Homo sapiens mRNA; cDNA DKFZp564E053 (from clone DKFZp564E053) /cds=UNKNOWN /gb=AL049261 /gi=4500009 /ug=Hs.133968 /len=2997 AL049261 post-GPI attachment to proteins 2 PGAP2 27315 NM_001145438 /// NM_001256235 /// NM_001256236 /// NM_001256237 /// NM_001256238 /// NM_001256239 /// NM_001256240 /// NM_001283038 /// NM_001283039 /// NM_001283040 /// NM_014489 /// NR_027016 /// NR_027017 /// NR_027018 /// NR_045923 /// NR_045925 /// NR_045926 /// NR_045927 /// NR_045929 /// NR_104270 /// NR_104271 /// NR_104272 /// XM_006718181 /// XM_006718182 /// XM_006718183 /// XM_006718184 /// XM_006718185 /// XM_006718186 /// XM_006718187 /// XM_006718188 /// XM_006718189 /// XM_006718190 /// XM_006718191 /// XM_006718192 /// XM_006718193 0006506 // GPI anchor biosynthetic process // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation 0000139 // Golgi membrane // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from sequence or structural similarity 42361_g_at AI588986 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI588986:tk15g03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2151124 /clone_end=3' /gb=AI588986 /gi=4598034 /ug=Hs.236209 /len=499 AI588986 coiled-coil alpha-helical rod protein 1 CCHCR1 54535 NM_001105563 /// NM_001105564 /// NM_019052 /// XM_005272832 /// XM_005272833 /// XM_005272835 /// XM_005272836 /// XM_005272839 /// XM_005272840 /// XM_005274987 /// XM_005274988 /// XM_005274990 /// XM_005274991 /// XM_005274994 /// XM_005274995 /// XM_005275137 /// XM_005275140 /// XM_005275265 /// XM_005275269 /// XM_005275422 /// XM_005275423 /// XM_006715119 /// XM_006725488 /// XM_006725702 /// XM_006725819 /// XM_006725911 /// XM_006726003 /// XM_006726004 0006611 // protein export from nucleus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 43427_at AI970898 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI970898:wr21c03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2488324 /clone_end=3' /gb=AI970898 /gi=5767724 /ug=Hs.234898 /len=382 AI970898 acetyl-CoA carboxylase beta ACACB 32 NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098 0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 43511_s_at AI201594 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI201594:qc02h12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1708487 /clone_end=3' /gb=AI201594 /gi=3754200 /ug=Hs.239333 /len=591 AI201594 arrestin, beta 1 ARRB1 408 NM_004041 /// NM_020251 /// XM_005273997 /// XM_005273998 /// XM_006718552 /// XM_006718553 /// XM_006718554 /// XM_006718555 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090240 // positive regulation of histone H4 acetylation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031143 // pseudopodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031896 // V2 vasopressin receptor binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 43544_at AA314406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA314406:EST186313 Homo sapiens cDNA, 5 end /clone=ATCC-111061 /clone_end=5' /gb=AA314406 /gi=1966806 /ug=Hs.24441 /len=541 AA314406 mediator complex subunit 16 MED16 10025 NM_005481 /// XM_006722600 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from direct assay /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 43934_at AA479495 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA479495:zv21d09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-754289 /clone_end=5' /gb=AA479495 /gi=2208051 /ug=Hs.25274 /len=534 AA479495 G protein-coupled receptor 137 GPR137 56834 NM_001170726 /// NM_001170880 /// NM_001170881 /// NM_001177358 /// NM_020155 /// XM_005274100 /// XM_005274101 /// XM_005274102 /// XM_005274104 /// XM_006718636 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 43977_at AI660497 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI660497:we67h06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2346203 /clone_end=3' /gb=AI660497 /gi=4764067 /ug=Hs.26570 /len=792 AI660497 transmembrane protein 161A TMEM161A 54929 NM_001256766 /// NM_017814 /// XM_005259976 0032526 // response to retinoic acid // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 44040_at AA524093 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA524093:ng33f04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-936607 /clone_end=3' /gb=AA524093 /gi=2265021 /ug=Hs.23158 /len=718 AA524093 F-box protein 41 /// uncharacterized LOC101927826 FBXO41 /// LOC101927826 150726 /// 101927826 NM_001080410 /// XM_005264158 /// XM_006711950 /// XR_245023 /// XR_245024 /// XR_249149 /// XR_249150 /// XR_251093 /// XR_251094 0005515 // protein binding // inferred from electronic annotation 44065_at AI937468 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI937468:wp77e05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2467808 /clone_end=3' /gb=AI937468 /gi=5676338 /ug=Hs.235849 /len=516 AI937468 RBPJ interacting and tubulin associated 1 RITA1 84934 NM_001286215 /// NM_032848 /// XM_005253972 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0051168 // nuclear export // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay 44111_at AI672363 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI672363:ty64c09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2283856 /clone_end=3' /gb=AI672363 /gi=4852094 /ug=Hs.26510 /len=787 AI672363 vacuolar protein sorting 33 homolog B (yeast) VPS33B 26276 NM_001289148 /// NM_001289149 /// NM_018668 /// XM_005254884 /// XM_005254887 /// XM_005254888 /// XM_006720471 0006810 // transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0032400 // melanosome localization // inferred from direct assay /// 0032418 // lysosome localization // inferred from direct assay /// 0061025 // membrane fusion // inferred from mutant phenotype /// 0070889 // platelet alpha granule organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 44120_at AI879381 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI879381:au50b03.x1 Homo sapiens cDNA /clone=IMAGE /gb=AI879381 /gi=5553430 /ug=Hs.27262 /len=586 AI879381 aarF domain containing kinase 2 ADCK2 90956 NM_052853 /// XM_006716170 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 44146_at AA045183 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA045183:zk66b08.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-487767 /clone_end=3' /gb=AA045183 /gi=1523385 /ug=Hs.28906 /len=548 AA045183 glucocorticoid modulatory element binding protein 2 GMEB2 26205 NM_012384 /// XM_005260202 /// XM_006723776 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 44563_at AI858000 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI858000:wj69b05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2408049 /clone_end=3' /gb=AI858000 /gi=5511616 /ug=Hs.30922 /len=715 AI858000 WD repeat containing, antisense to TP53 WRAP53 55135 NM_001143990 /// NM_001143991 /// NM_001143992 /// NM_018081 /// XR_429818 0032203 // telomere formation via telomerase // inferred from mutant phenotype /// 0051973 // positive regulation of telomerase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 44617_at AI431902 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI431902:ti26e07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2131620 /clone_end=3' /gb=AI431902 /gi=4306432 /ug=Hs.33533 /len=566 AI431902 2-oxoglutarate and iron-dependent oxygenase domain containing 2 OGFOD2 79676 NM_024623 0055114 // oxidation-reduction process // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 44654_at AI669655 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI669655:wc12a05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2314928 /clone_end=3' /gb=AI669655 /gi=4834429 /ug=Hs.30251 /len=649 AI669655 glucose 6 phosphatase, catalytic, 3 G6PC3 92579 NM_138387 /// NR_028581 /// NR_028582 /// XM_006722179 0005975 // carbohydrate metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051156 // glucose 6-phosphate metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004346 // glucose-6-phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 44669_at N31716 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N31716:yy15c12.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-271318 /clone_end=3' /gb=N31716 /gi=1152115 /ug=Hs.31754 /len=624 N31716 succinate dehydrogenase complex assembly factor 1 SDHAF1 644096 NM_001042631 0016226 // iron-sulfur cluster assembly // non-traceable author statement /// 0034553 // mitochondrial respiratory chain complex II assembly // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation 44673_at N53555 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N53555:yv43e09.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-245512 /clone_end=3' /gb=N53555 /gi=1194721 /ug=Hs.31869 /len=680 N53555 sialic acid binding Ig-like lectin 1, sialoadhesin SIGLEC1 6614 NM_023068 /// XM_006723610 /// XM_006723611 /// XM_006723612 /// XM_006723613 0006897 // endocytosis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0070234 // positive regulation of T cell apoptotic process // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement 44696_at AA915989 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA915989:oh86f07.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1473925 /clone_end=3' /gb=AA915989 /gi=3055381 /ug=Hs.3376 /len=528 AA915989 TBC1 domain family, member 13 TBC1D13 54662 NM_001286772 /// NM_018201 /// XM_005252060 /// XM_006717147 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 44702_at R77097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R77097:yi64h07.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-144061 /clone_end=5' /gb=R77097 /gi=851729 /ug=Hs.9291 /len=514 R77097 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) SYDE1 85360 NM_033025 /// XM_005260126 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032862 // activation of Rho GTPase activity // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 44783_s_at R61374 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R61374:yh15e02.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-37665 /clone_end=3' /gb=R61374 /gi=832069 /ug=Hs.234434 /len=434 R61374 hes-related family bHLH transcription factor with YRPW motif 1 HEY1 23462 NM_001040708 /// NM_001282851 /// NM_012258 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003190 // atrioventricular valve formation // inferred from sequence or structural similarity /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from sequence or structural similarity /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036304 // umbilical cord morphogenesis // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000820 // negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from direct assay /// 2001212 // regulation of vasculogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 44790_s_at AI129310 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI129310:qc48a05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1712816 /clone_end=3' /gb=AI129310 /gi=3597824 /ug=Hs.234923 /len=811 AI129310 KIAA0226-like KIAA0226L 80183 NM_001286761 /// NM_001286762 /// NM_001286763 /// NM_001286764 /// NM_001286765 /// NM_001286766 /// NM_025113 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation 44822_s_at AW003889 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW003889:ws61f12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2501711 /clone_end=3' /gb=AW003889 /gi=5850805 /ug=Hs.236430 /len=478 AW003889 mesoderm induction early response 1, family member 2 MIER2 54531 NM_017550 /// XM_005259582 /// XM_006722769 /// XM_006722770 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation 45288_at AA209239 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA209239:zq85h01.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-648433 /clone_end=5' /gb=AA209239 /gi=1807254 /ug=Hs.20220 /len=762 AA209239 abhydrolase domain containing 6 ABHD6 57406 NM_020676 /// XM_005265334 /// XM_005265335 /// XM_005265336 0008152 // metabolic process // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 2000124 // regulation of endocannabinoid signaling pathway // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation 45297_at AI417917 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI417917:tg55d04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2112679 /clone_end=3' /gb=AI417917 /gi=4261421 /ug=Hs.20733 /len=662 AI417917 EH-domain containing 2 EHD2 30846 NM_014601 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 45526_g_at AI246641 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI246641:qn65h10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1903171 /clone_end=3' /gb=AI246641 /gi=3842038 /ug=Hs.235980 /len=451 AI246641 N(alpha)-acetyltransferase 60, NatF catalytic subunit NAA60 79903 NM_001083600 /// NM_001083601 /// NM_024845 /// XM_006720949 /// XM_006720950 /// XM_006720951 /// XM_006720952 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017196 // N-terminal peptidyl-methionine acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation 45572_s_at AW009695 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW009695:ws86b07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2504821 /clone_end=3' /gb=AW009695 /gi=5858473 /ug=Hs.238296 /len=491 AW009695 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 GGA1 26088 NM_001001560 /// NM_001001561 /// NM_001172687 /// NM_001172688 /// NM_013365 /// XM_005261517 /// XM_005261518 /// XM_005261520 /// XM_005261522 /// XM_006724228 /// XM_006724229 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 45633_at AI421812 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI421812:tf55a07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2103156 /clone_end=3' /gb=AI421812 /gi=4267743 /ug=Hs.47125 /len=556 AI421812 GINS complex subunit 3 (Psf3 homolog) GINS3 64785 NM_001126129 /// NM_001126130 /// NM_022770 0006260 // DNA replication // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 45653_at AW026481 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW026481:wv14a04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-990913 /clone_end=3' /gb=AW026481 /gi=5880011 /ug=Hs.48396 /len=496 AW026481 potassium channel tetramerization domain containing 13 KCTD13 253980 NM_178863 /// NR_110933 0006260 // DNA replication // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 45687_at AA161130 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA161130:zo59b05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-591153 /clone_end=3' /gb=AA161130 /gi=1735440 /ug=Hs.50344 /len=604 AA161130 proline rich 14 PRR14 78994 NM_024031 /// XM_005255566 45714_at AA436930 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA436930:zv72b02.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-759147 /clone_end=5' /gb=AA436930 /gi=2141844 /ug=Hs.239759 /len=586 AA436930 host cell factor C1 regulator 1 (XPO1 dependent) HCFC1R1 54985 NM_001002017 /// NM_001002018 /// NM_001288665 /// NM_001288666 /// NM_001288667 /// NM_001288668 /// NM_017885 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 45749_at AA400206 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA400206:zu69a02.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-743210 /clone_end=5' /gb=AA400206 /gi=2054077 /ug=Hs.3074 /len=579 AA400206 family with sequence similarity 65, member A FAM65A 79567 NM_001193522 /// NM_001193523 /// NM_001193524 /// NM_024519 /// XM_006721269 /// XM_006721270 0007165 // signal transduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation 45828_at AI768100 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI768100:wg81b02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2371467 /clone_end=3' /gb=AI768100 /gi=5234609 /ug=Hs.6045 /len=573 AI768100 ATP5S-like ATP5SL 55101 NM_001167867 /// NM_001167868 /// NM_001167869 /// NM_001167870 /// NM_001167871 /// NM_018035 /// NR_030765 /// XM_006723258 0005739 // mitochondrion // inferred from electronic annotation 46142_at AI003763 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI003763:ou91e02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1635194 /clone_end=3' /gb=AI003763 /gi=3213273 /ug=Hs.58362 /len=594 AI003763 lipase maturation factor 1 LMF1 64788 NM_022773 /// NR_033645 /// NR_033646 /// NR_036442 /// XM_006720926 /// XM_006720927 /// XM_006720928 /// XM_006720929 /// XM_006720930 /// XR_429646 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0009306 // protein secretion // inferred from electronic annotation /// 0033578 // protein glycosylation in Golgi // inferred from electronic annotation /// 0034382 // chylomicron remnant clearance // inferred from electronic annotation /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from electronic annotation /// 0090207 // regulation of triglyceride metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 46167_at W22690 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W22690:71G4 Homo sapiens cDNA /clone=(not-directional) /gb=W22690 /gi=1299523 /ug=Hs.5990 /len=678 W22690 MROH7-TTC4 readthrough (NMD candidate) /// tetratricopeptide repeat domain 4 MROH7-TTC4 /// TTC4 7268 /// 100527960 NM_001291333 /// NM_004623 /// NR_037639 /// NR_037640 /// NR_037641 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 46256_at AA522670 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA522670:ni39a05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-979184 /clone_end=3' /gb=AA522670 /gi=2263382 /ug=Hs.7247 /len=684 AA522670 splA/ryanodine receptor domain and SOCS box containing 3 SPSB3 90864 NM_080861 /// XM_005255673 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 46270_at AL039447 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL039447:DKFZp434N1010_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434N1010 /clone_end=3' /gb=AL039447 /gi=5408497 /ug=Hs.75425 /len=841 AL039447 ubiquitin associated protein 1 UBAP1 51271 NM_001171201 /// NM_001171202 /// NM_001171203 /// NM_001171204 /// NM_016525 /// NR_033243 /// XM_006716779 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype 0000813 // ESCRT I complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay 46323_at AL120741 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL120741:DKFZp762K231_r1 Homo sapiens cDNA, 5 end /clone=DKFZp762K231 /clone_end=5' /gb=AL120741 /gi=5926641 /ug=Hs.8859 /len=707 AL120741 calcium activated nucleotidase 1 CANT1 124583 NM_001159772 /// NM_001159773 /// NM_138793 /// XM_005257020 /// XM_005257021 /// XM_005257022 /// XM_006721682 /// XM_006721683 /// XR_243633 0007165 // signal transduction // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030166 // proteoglycan biosynthetic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016462 // pyrophosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 46665_at AI949392 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI949392:wq11a04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2470926 /clone_end=3' /gb=AI949392 /gi=5741790 /ug=Hs.7188 /len=596 AI949392 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C SEMA4C 54910 NM_017789 /// XM_006712606 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0021535 // cell migration in hindbrain // inferred from sequence or structural similarity /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from direct assay /// 0042692 // muscle cell differentiation // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 46947_at T87245 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. T87245:yd91b02.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-115563 /clone_end=5' /gb=T87245 /gi=715597 /ug=Hs.16336 /len=412 T87245 guanine nucleotide binding protein-like 3 (nucleolar)-like GNL3L 54552 NM_001184819 /// NM_019067 0006184 // GTP catabolic process // not recorded /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 47069_at AA533284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA533284:nj66e12.s1 Homo sapiens cDNA /clone=IMAGE-997486 /gb=AA533284 /gi=2277380 /ug=Hs.79601 /len=613 AA533284 proline rich 5 (renal) PRR5 55615 NM_001017528 /// NM_001017529 /// NM_001017530 /// NM_001198721 /// NM_015366 /// NM_181333 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031932 // TORC2 complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 47083_at AI280108 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI280108:qh85g01.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1853808 /clone_end=3' /gb=AI280108 /gi=3918341 /ug=Hs.81057 /len=504 AI280108 chromosome 7 open reading frame 26 C7orf26 79034 NM_024067 /// XM_005249845 /// XR_242101 47105_at AA886893 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA886893:oj26h05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1493337 /clone_end=3' /gb=AA886893 /gi=3002001 /ug=Hs.8575 /len=479 AA886893 dihydrouridine synthase 2 DUS2 54920 NM_001271762 /// NM_001271763 /// NM_017803 0002943 // tRNA dihydrouridine synthesis // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017150 // tRNA dihydrouridine synthase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 47530_at AA748492 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA748492:ny01g12.s1 Homo sapiens cDNA /clone=IMAGE-1270534 /gb=AA748492 /gi=2788450 /ug=Hs.9196 /len=439 AA748492 chromosome 9 open reading frame 156 C9orf156 51531 NM_016481 /// XM_005252047 /// XM_005252048 /// XM_005252049 /// XM_005252050 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 47550_at N21184 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N21184:yx41a10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-264282 /clone_end=3' /gb=N21184 /gi=1126354 /ug=Hs.93605 /len=619 N21184 leucine zipper, putative tumor suppressor 1 LZTS1 11178 NM_021020 /// XM_005273394 /// XM_006716281 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048814 // regulation of dendrite morphogenesis // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 47553_at AA813332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA813332:ai81a12.s1 Homo sapiens cDNA, 3 end /clone=1377214 /clone_end=3' /gb=AA813332 /gi=2883317 /ug=Hs.93836 /len=536 AA813332 deafness, autosomal recessive 31 DFNB31 25861 NM_001083885 /// NM_001173425 /// NM_015404 /// XM_005251895 /// XM_005251897 /// XM_005251898 /// XM_006717041 0001895 // retina homeostasis // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0060122 // inner ear receptor stereocilium organization // inferred from sequence or structural similarity 0002142 // stereocilia ankle link complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032421 // stereocilium bundle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 47560_at AI525402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI525402:PT1.1_07_C06.r Homo sapiens cDNA, 5 end /clone_end=5' /gb=AI525402 /gi=4439537 /ug=Hs.94229 /len=653 AI525402 latrophilin 1 LPHN1 22859 NM_001008701 /// NM_014921 /// XM_005259818 /// XM_005259819 /// XM_006722688 /// XM_006722689 /// XM_006722690 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016524 // latrotoxin receptor activity // inferred from sequence or structural similarity /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 47571_at AA004757 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA004757:zh96g05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-429176 /clone_end=3' /gb=AA004757 /gi=1448325 /ug=Hs.95026 /len=447 AA004757 zinc finger protein 236 ZNF236 7776 NM_007345 /// XM_005266762 /// XM_006722541 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from expression pattern 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 47608_at AI697401 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI697401:tq18h09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2209217 /clone_end=3' /gb=AI697401 /gi=4985301 /ug=Hs.9741 /len=639 AI697401 tight junction associated protein 1 (peripheral) TJAP1 93643 NM_001146016 /// NM_001146017 /// NM_001146018 /// NM_001146019 /// NM_001146020 /// NM_080604 /// NR_027394 /// XM_006715249 /// XM_006715250 /// XM_006715251 /// XM_006715252 /// XM_006715253 /// XM_006715254 /// XM_006715255 /// XM_006715256 /// XM_006715257 /// XM_006715258 /// XM_006715259 /// XM_006715260 /// XM_006715261 /// XM_006715262 /// XM_006715263 /// XM_006715264 /// XM_006715265 /// XM_006715266 /// XM_006715267 /// XM_006715268 /// XM_006715269 /// XM_006715270 /// XM_006715271 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 47773_at AA836114 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA836114:od15c12.s1 Homo sapiens cDNA /clone=IMAGE-1368022 /gb=AA836114 /gi=2910433 /ug=Hs.62767 /len=554 AA836114 F-box protein 42 FBXO42 54455 NM_018994 /// XM_006710698 0005515 // protein binding // inferred from electronic annotation 48030_i_at H93077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H93077:yv05a04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-241806 /clone_end=3' /gb=H93077 /gi=1099405 /ug=Hs.10235 /len=604 H93077 fatty acid hydroxylase domain containing 2 FAXDC2 10826 NM_016348 /// NM_032385 /// XM_005268356 /// XM_005268358 /// XM_006714753 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 48031_r_at H93077 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H93077:yv05a04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-241806 /clone_end=3' /gb=H93077 /gi=1099405 /ug=Hs.10235 /len=604 H93077 fatty acid hydroxylase domain containing 2 FAXDC2 10826 NM_016348 /// NM_032385 /// XM_005268356 /// XM_005268358 /// XM_006714753 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 48106_at H14241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H14241:ym63e09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-163624 /clone_end=5' /gb=H14241 /gi=879061 /ug=Hs.109297 /len=552 H14241 solute carrier family 48 (heme transporter), member 1 SLC48A1 55652 NM_017842 /// XM_005269016 0006810 // transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0015232 // heme transporter activity // inferred from electronic annotation 48117_at AA160496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA160496:zo73a03.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-592492 /clone_end=3' /gb=AA160496 /gi=1735863 /ug=Hs.110407 /len=542 AA160496 coiled-coil domain containing 101 CCDC101 112869 NM_138414 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0071169 // establishment of protein localization to chromatin // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay 48531_at AA522816 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA522816:ni40e12.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-979342 /clone_end=3' /gb=AA522816 /gi=2263528 /ug=Hs.173789 /len=564 AA522816 TNFAIP3 interacting protein 2 TNIP2 79155 NM_001161527 /// NM_001292016 /// NM_024309 /// XM_005248010 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0023035 // CD40 signaling pathway // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // inferred from sequence or structural similarity /// 0034162 // toll-like receptor 9 signaling pathway // inferred from sequence or structural similarity /// 0043032 // positive regulation of macrophage activation // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050871 // positive regulation of B cell activation // inferred from sequence or structural similarity /// 0070498 // interleukin-1-mediated signaling pathway // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from direct assay /// 0031593 // polyubiquitin binding // inferred from direct assay 48580_at U55777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. U55777:HSU55777 Homo sapiens cDNA /clone=37698 /gb=U55777 /gi=1354513 /ug=Hs.180933 /len=1593 U55777 CXXC finger protein 1 CXXC1 30827 NM_001101654 /// NM_014593 /// XM_006722446 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051568 // histone H3-K4 methylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0045322 // unmethylated CpG binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 48612_at AA225490 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA225490:nc25b01.r1 Homo sapiens cDNA /clone=IMAGE-1009129 /gb=AA225490 /gi=1846817 /ug=Hs.80115 /len=539 AA225490 NEDD4 binding protein 1 N4BP1 9683 NM_153029 /// XM_005256262 /// XM_006721351 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 48659_at W60802 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W60802:zd27e02.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-341882 /clone_end=3' /gb=W60802 /gi=1367646 /ug=Hs.8595 /len=588 W60802 migration and invasion inhibitory protein MIIP 60672 NM_001025374 /// NM_021933 /// XM_005263487 48808_at AI144299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI144299:qb59h06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1704443 /clone_end=3' /gb=AI144299 /gi=3666108 /ug=Hs.106843 /len=765 AI144299 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 48825_at AA887083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA887083:oi13d10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1476403 /clone_end=3' /gb=AA887083 /gi=3002191 /ug=Hs.108183 /len=791 AA887083 inhibitor of growth family, member 4 ING4 51147 NM_001127582 /// NM_001127583 /// NM_001127584 /// NM_001127585 /// NM_001127586 /// NM_016162 /// NM_198287 /// XM_005253698 /// XR_242982 /// XR_242983 0006260 // DNA replication // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006473 // protein acetylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045926 // negative regulation of growth // inferred from direct assay 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 49049_at N92708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N92708:zb44c04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-306438 /clone_end=3' /gb=N92708 /gi=1265017 /ug=Hs.32374 /len=668 N92708 deltex 3, E3 ubiquitin ligase DTX3 196403 NM_001286245 /// NM_001286246 /// NM_178502 /// XM_005268697 /// XM_005268698 /// XM_005268700 /// XM_005268703 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 49051_g_at N92708 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N92708:zb44c04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-306438 /clone_end=3' /gb=N92708 /gi=1265017 /ug=Hs.32374 /len=668 N92708 deltex 3, E3 ubiquitin ligase DTX3 196403 NM_001286245 /// NM_001286246 /// NM_178502 /// XM_005268697 /// XM_005268698 /// XM_005268700 /// XM_005268703 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 49077_at AL040538 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL040538:DKFZp434H0614_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434H0614 /clone_end=3' /gb=AL040538 /gi=5409486 /ug=Hs.63304 /len=870 AL040538 protein phosphatase methylesterase 1 PPME1 51400 NM_001271593 /// NM_016147 /// XR_428916 0006482 // protein demethylation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from direct assay /// 0051722 // protein C-terminal methylesterase activity // inferred from direct assay /// 0052689 // carboxylic ester hydrolase activity // inferred from electronic annotation 49111_at N80935 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N80935:zb07g06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-301402 /clone_end=3' /gb=N80935 /gi=1243636 /ug=Hs.22483 /len=527 N80935 arrestin, beta 1 ARRB1 408 NM_004041 /// NM_020251 /// XM_005273997 /// XM_005273998 /// XM_006718552 /// XM_006718553 /// XM_006718554 /// XM_006718555 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007602 // phototransduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032717 // negative regulation of interleukin-8 production // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034393 // positive regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090240 // positive regulation of histone H4 acetylation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031143 // pseudopodium // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031896 // V2 vasopressin receptor binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from electronic annotation /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 49306_at AI890191 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI890191:wm79f05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2442177 /clone_end=3' /gb=AI890191 /gi=5595355 /ug=Hs.239937 /len=674 AI890191 Ras association (RalGDS/AF-6) domain family member 4 RASSF4 83937 NM_032023 /// NM_178145 /// XM_005271833 /// XM_005271835 /// XM_006718013 /// XM_006718014 /// XM_006718015 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 49327_at AI492888 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI492888:th78c09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2124784 /clone_end=3' /gb=AI492888 /gi=4393891 /ug=Hs.19306 /len=596 AI492888 sirtuin 3 SIRT3 23410 NM_001017524 /// NM_012239 /// XM_005252835 0006471 // protein ADP-ribosylation // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0034983 // peptidyl-lysine deacetylation // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003950 // NAD+ ADP-ribosyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation 49329_at N38751 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N38751:yy42c07.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-273900 /clone_end=3' /gb=N38751 /gi=1161958 /ug=Hs.181341 /len=579 N38751 kelch-like family member 22 KLHL22 84861 NM_032775 /// NR_033825 /// XM_006724342 /// XM_006724343 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 49452_at AI057637 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI057637:oy31h06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1667483 /clone_end=3' /gb=AI057637 /gi=3331503 /ug=Hs.21305 /len=599 AI057637 acetyl-CoA carboxylase beta ACACB 32 NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098 0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 49485_at W22625 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W22625:71E5 Homo sapiens cDNA /clone=(not-directional) /gb=W22625 /gi=1299507 /ug=Hs.21807 /len=632 W22625 PR domain containing 4 PRDM4 11108 NM_012406 /// XM_005268593 /// XM_006719205 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 49679_s_at AA243774 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA243774:zr67d03.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-668453 /clone_end=5' /gb=AA243774 /gi=1874594 /ug=Hs.235164 /len=533 AA243774 MMP24 antisense RNA 1 MMP24-AS1 101410538 NR_102705 /// NR_102706 49878_at AA523441 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA523441:ng30d08.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-936303 /clone_end=3' /gb=AA523441 /gi=2264153 /ug=Hs.100915 /len=594 AA523441 peroxisomal biogenesis factor 16 PEX16 9409 NM_004813 /// NM_057174 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0022615 // protein to membrane docking // inferred from direct assay /// 0032581 // ER-dependent peroxisome organization // inferred from direct assay /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0070972 // protein localization to endoplasmic reticulum // inferred from direct assay 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 50221_at AI524138 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI524138:th09f03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2117789 /clone_end=3' /gb=AI524138 /gi=4438273 /ug=Hs.23391 /len=834 AI524138 transcription factor EB TFEB 7942 NM_001167827 /// NM_001271943 /// NM_001271944 /// NM_001271945 /// NM_007162 /// XM_005249411 /// XM_005249412 /// XM_006715212 /// XM_006715213 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 50277_at AW001443 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW001443:wu31e12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-990785 /clone_end=3' /gb=AW001443 /gi=5848359 /ug=Hs.239110 /len=490 AW001443 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 GGA1 26088 NM_001001560 /// NM_001001561 /// NM_001172687 /// NM_001172688 /// NM_013365 /// XM_005261517 /// XM_005261518 /// XM_005261520 /// XM_005261522 /// XM_006724228 /// XM_006724229 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 50314_i_at AI761506 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI761506:wi61b11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2394717 /clone_end=3' /gb=AI761506 /gi=5177173 /ug=Hs.239692 /len=544 AI761506 chromosome 20 open reading frame 27 C20orf27 54976 NM_001039140 /// NM_001258429 /// NM_001258430 /// NM_017874 /// NR_047675 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 50374_at AA150503 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA150503:zl08g04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-491766 /clone_end=3' /gb=AA150503 /gi=1722017 /ug=Hs.24435 /len=631 AA150503 oxidoreductase-like domain containing 1 OXLD1 339229 NM_001039842 0005739 // mitochondrion // inferred from electronic annotation 50376_at AI278629 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI278629:qm47b10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1891867 /clone_end=3' /gb=AI278629 /gi=3916863 /ug=Hs.24545 /len=540 AI278629 zinc finger protein 444 ZNF444 55311 NM_001253792 /// NM_018337 /// XM_005259034 /// XM_005259035 /// XM_005259036 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 50400_at AI743990 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI743990:wc32d07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2316877 /clone_end=3' /gb=AI743990 /gi=5112278 /ug=Hs.24859 /len=583 AI743990 polyamine oxidase (exo-N4-amino) PAOX 196743 NM_152911 /// NM_207125 /// NM_207126 /// NM_207127 /// NM_207128 /// NM_207129 /// NR_109763 /// NR_109764 /// NR_109765 /// NR_109766 0006184 // GTP catabolic process // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008215 // spermine metabolic process // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from direct assay /// 0009447 // putrescine catabolic process // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042254 // ribosome biogenesis // /// 0044065 // regulation of respiratory system process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046203 // spermidine catabolic process // inferred from direct assay /// 0046208 // spermine catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070129 // regulation of mitochondrial translation // inferred from mutant phenotype /// 1901307 // positive regulation of spermidine biosynthetic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // /// 0003924 // GTPase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046592 // polyamine oxidase activity // inferred from direct assay /// 0052899 // N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052901 // spermine:oxygen oxidoreductase (spermidine-forming) activity // inferred from electronic annotation /// 0052902 // spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity // inferred from electronic annotation /// 0052903 // N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // inferred from electronic annotation /// 0052904 // N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity // traceable author statement 50965_at AI690165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI690165:tx27h06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2270843 /clone_end=3' /gb=AI690165 /gi=4901459 /ug=Hs.3797 /len=494 AI690165 RAB26, member RAS oncogene family RAB26 25837 NM_014353 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from sequence or structural similarity /// 0035272 // exocrine system development // inferred from mutant phenotype /// 0035272 // exocrine system development // inferred from sequence or structural similarity /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0045055 // regulated secretory pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from sequence or structural similarity /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from mutant phenotype /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019002 // GMP binding // inferred from mutant phenotype 51146_at AA203365 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA203365:zx56a06.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-446482 /clone_end=5' /gb=AA203365 /gi=1799134 /ug=Hs.26994 /len=847 AA203365 phosphatidylinositol glycan anchor biosynthesis, class V PIGV 55650 NM_001202554 /// NM_017837 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from genetic interaction /// 0006506 // GPI anchor biosynthetic process // inferred from mutant phenotype /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from genetic interaction /// 0097502 // mannosylation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000030 // mannosyltransferase activity // inferred from genetic interaction /// 0000030 // mannosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation 51158_at AI801973 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI801973:tx29d05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2270985 /clone_end=3' /gb=AI801973 /gi=5367445 /ug=Hs.27373 /len=532 AI801973 family with sequence similarity 174, member B FAM174B 400451 NM_207446 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 51176_at AA131335 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA131335:zo08f01.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-567097 /clone_end=3' /gb=AA131335 /gi=1692833 /ug=Hs.28166 /len=552 AA131335 mediator complex subunit 27 MED27 9442 NM_001253881 /// NM_001253882 /// NM_004269 /// XM_005272236 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay 51192_at AA134926 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA134926:zo23d02.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-587715 /clone_end=3' /gb=AA134926 /gi=1696027 /ug=Hs.29173 /len=535 AA134926 slingshot protein phosphatase 3 SSH3 54961 NM_017857 /// NM_018276 /// XM_005274070 /// XM_005274071 /// XM_005274072 /// XM_006718592 /// XR_247205 /// XR_247206 0006470 // protein dephosphorylation // not recorded /// 0008064 // regulation of actin polymerization or depolymerization // not recorded /// 0010591 // regulation of lamellipodium assembly // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003779 // actin binding // not recorded /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 51200_at AI744084 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI744084:wc36b05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2317233 /clone_end=3' /gb=AI744084 /gi=5112372 /ug=Hs.30783 /len=524 AI744084 chromosome 19 open reading frame 60 C19orf60 55049 NM_001100418 /// NM_001100419 /// NM_017967 /// XM_005259977 0005515 // protein binding // inferred from physical interaction 51226_at N53536 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N53536:yz26h01.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-284209 /clone_end=3' /gb=N53536 /gi=1194702 /ug=Hs.33540 /len=543 N53536 RP11-10N23.4 51228_at N36928 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N36928:yy38e06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-273538 /clone_end=3' /gb=N36928 /gi=1158070 /ug=Hs.33540 /len=582 N36928 RNA binding motif protein 12B RBM12B 389677 NM_203390 /// XM_005250915 /// XM_005250916 /// XM_006716556 /// XM_006716557 /// XM_006716558 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 51774_s_at AW014299 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW014299:UI-H-BI0p-aax-a-07-0-UI.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-2710573 /clone_end=3' /gb=AW014299 /gi=5863056 /ug=Hs.238968 /len=391 AW014299 ubiquitin-conjugating enzyme E2D 4 (putative) UBE2D4 51619 NM_015983 /// XM_005249772 /// XM_006715734 /// XM_006715735 /// XM_006715736 /// XM_006715737 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 52005_at AA422049 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA422049:zv28g05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-755000 /clone_end=3' /gb=AA422049 /gi=2100865 /ug=Hs.40780 /len=668 AA422049 widely interspaced zinc finger motifs WIZ 58525 NM_021241 /// XM_005260004 /// XM_005260005 /// XM_005260006 /// XM_005260007 /// XM_005260008 /// XM_005260009 /// XM_005260010 /// XM_005260011 /// XM_005260012 /// XM_006722828 0010571 // positive regulation of nuclear cell cycle DNA replication // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0070208 // protein heterotrimerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 52078_at AI828080 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI828080:wk31e09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2413960 /clone_end=3' /gb=AI828080 /gi=5448751 /ug=Hs.4293 /len=544 AI828080 transmembrane protein 222 TMEM222 84065 NM_032125 /// NR_037576 /// NR_037577 /// NR_037580 /// XM_006710942 /// XM_006710943 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 52159_at W93807 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W93807:zd97g03.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-357460 /clone_end=3' /gb=W93807 /gi=1422999 /ug=Hs.46907 /len=607 W93807 HemK methyltransferase family member 1 HEMK1 51409 NM_016173 /// XM_005265218 /// XM_005265219 0006306 // DNA methylation // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0031167 // rRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 52164_at AA065185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA065185:zm50e09.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-529096 /clone_end=3' /gb=AA065185 /gi=1559080 /ug=Hs.47008 /len=605 AA065185 chromosome 11 open reading frame 24 C11orf24 53838 NM_022338 /// XM_005274053 /// XM_005274054 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 52169_at AI302185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI302185:qn58d02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1902435 /clone_end=3' /gb=AI302185 /gi=3961531 /ug=Hs.4789 /len=522 AI302185 STE20-related kinase adaptor alpha STRADA 92335 NM_001003786 /// NM_001003787 /// NM_001003788 /// NM_001165969 /// NM_001165970 /// NM_153335 /// XM_005257797 /// XM_005257798 /// XM_005257799 /// XM_005257800 /// XM_005257801 /// XM_005257803 /// XR_243687 /// XR_243688 0006468 // protein phosphorylation // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0032147 // activation of protein kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from direct assay 52255_s_at AI984221 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI984221:wz57c09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2562160 /clone_end=3' /gb=AI984221 /gi=5811440 /ug=Hs.235368 /len=515 AI984221 collagen, type V, alpha 3 COL5A3 50509 NM_015719 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0043588 // skin development // non-traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from electronic annotation 52285_f_at AW002970 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW002970:wr03h11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2480517 /clone_end=3' /gb=AW002970 /gi=5849976 /ug=Hs.236940 /len=570 AW002970 centrosomal protein 76kDa CEP76 79959 NM_001271989 /// NM_024899 /// NR_073537 /// XM_005258149 /// XM_005258150 /// XM_006722356 /// XM_006722357 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0046599 // regulation of centriole replication // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 52651_at AI806793 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI806793:wf15d05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2350665 /clone_end=3' /gb=AI806793 /gi=5393359 /ug=Hs.239450 /len=555 AI806793 collagen, type VIII, alpha 2 COL8A2 1296 NM_001294347 /// NM_005202 /// XM_005270477 /// XM_005270478 /// XM_005270479 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 52731_at AI359466 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI359466:qy31h06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2013659 /clone_end=3' /gb=AI359466 /gi=4111087 /ug=Hs.7995 /len=469 AI359466 autophagy/beclin-1 regulator 1 AMBRA1 55626 NM_001267782 /// NM_001267783 /// NM_017749 /// XM_005253009 /// XM_005253011 /// XM_005253012 /// XM_005253014 /// XM_006718259 /// XM_006718260 0006914 // autophagy // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 52741_at AI962879 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI962879:wt24c06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2508394 /clone_end=3' /gb=AI962879 /gi=5755592 /ug=Hs.81920 /len=490 AI962879 tRNA methyltransferase 61 homolog A (S. cerevisiae) TRMT61A 115708 NM_152307 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0031515 // tRNA (m1A) methyltransferase complex // inferred from electronic annotation 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016429 // tRNA (adenine-N1-)-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 52837_at AL047020 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL047020:DKFZp586N1517_s1 Homo sapiens cDNA, 3 end /clone=DKFZp586N1517 /clone_end=3' /gb=AL047020 /gi=5435076 /ug=Hs.6829 /len=754 AL047020 KIAA1644 KIAA1644 85352 NM_001099294 /// XM_005261790 /// XM_006724344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 52940_at AA085764 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA085764:zk71e09.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-488296 /clone_end=3' /gb=AA085764 /gi=1629226 /ug=Hs.11809 /len=525 AA085764 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain SIGIRR 59307 NM_001135053 /// NM_001135054 /// NM_021805 /// XM_005253044 /// XM_005253045 /// XM_005253046 /// XM_005253047 /// XM_005253048 /// XR_242815 /// XR_242816 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045079 // negative regulation of chemokine biosynthetic process // inferred from sequence or structural similarity 0016020 // membrane // inferred from mutant phenotype /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 52975_at AA534894 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA534894:nf82d11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-926421 /clone_end=3' /gb=AA534894 /gi=2279147 /ug=Hs.4914 /len=602 AA534894 multivesicular body subunit 12B MVB12B 89853 NM_001011703 /// NM_033446 /// XM_005252297 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042058 // regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from mutant phenotype /// 0043130 // ubiquitin binding // inferred from direct assay 53071_s_at AI885411 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI885411:wl93e01.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2432472 /clone_end=3' /gb=AI885411 /gi=5590575 /ug=Hs.54558 /len=586 AI885411 2-oxoglutarate and iron-dependent oxygenase domain containing 3 OGFOD3 79701 NM_024648 /// NM_175902 /// NR_033265 /// XR_430034 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 53076_at AI040029 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI040029:ox97g11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1664324 /clone_end=3' /gb=AI040029 /gi=3279223 /ug=Hs.54702 /len=922 AI040029 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 B4GALT7 11285 NM_007255 /// XM_005265805 /// XM_006714815 /// XM_006714816 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0008378 // galactosyltransferase activity // inferred from direct assay /// 0008378 // galactosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046525 // xylosylprotein 4-beta-galactosyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 53202_at AA402435 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA402435:zt60g10.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-726786 /clone_end=5' /gb=AA402435 /gi=2057299 /ug=Hs.59594 /len=529 AA402435 chromosome 7 open reading frame 25 /// proteasome (prosome, macropain) subunit, alpha type, 2 C7orf25 /// PSMA2 5683 /// 79020 NM_001099858 /// NM_002787 /// NM_024054 /// XM_005249844 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 53720_at AI862559 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI862559:wj15e06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2402914 /clone_end=3' /gb=AI862559 /gi=5526666 /ug=Hs.12151 /len=574 AI862559 chromosome 19 open reading frame 66 C19orf66 55337 NM_018381 /// XM_006722786 /// XM_006722787 /// XM_006722788 53912_at AI668643 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI668643:zb13f10.x5 Homo sapiens cDNA, 3 end /clone=IMAGE-301963 /clone_end=3' /gb=AI668643 /gi=4827951 /ug=Hs.15827 /len=601 AI668643 sorting nexin 11 SNX11 29916 NM_013323 /// NM_152244 /// XM_005257260 /// XM_005257261 /// XM_005257262 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from mutant phenotype 0005768 // endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 1901981 // phosphatidylinositol phosphate binding // inferred from direct assay 53968_at AI869988 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI869988:wl63e02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2429594 /clone_end=3' /gb=AI869988 /gi=5543956 /ug=Hs.6259 /len=541 AI869988 integrator complex subunit 5 INTS5 80789 NM_030628 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 53987_at AL041852 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL041852:DKFZp434D0918_r1 Homo sapiens cDNA, 5 end /clone=DKFZp434D0918 /clone_end=5' /gb=AL041852 /gi=5421198 /ug=Hs.6343 /len=661 AL041852 RAN binding protein 10 RANBP10 57610 NM_020850 /// XM_005256070 /// XM_005256072 /// XM_006721238 /// XM_006721239 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0032316 // regulation of Ran GTPase activity // inferred from electronic annotation /// 0032853 // positive regulation of Ran GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005087 // Ran guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation 53991_at AA127623 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA127623:zk89a12.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-489982 /clone_end=5' /gb=AA127623 /gi=1686976 /ug=Hs.6385 /len=698 AA127623 DENN/MADD domain containing 2A DENND2A 27147 NM_015689 /// XM_005249976 /// XM_005249977 /// XM_005249978 /// XM_005249979 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 54037_at AL041451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL041451:DKFZp434E1117_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434E1117 /clone_end=3' /gb=AL041451 /gi=5420802 /ug=Hs.6657 /len=657 AL041451 Hermansky-Pudlak syndrome 4 HPS4 89781 NM_022081 /// NM_152840 /// NM_152841 /// NM_152842 /// NM_152843 /// NR_073135 /// NR_073136 /// XM_006724353 /// XM_006724354 /// XM_006724355 /// XM_006724356 /// XM_006724357 /// XM_006724358 /// XM_006724359 /// XM_006724360 /// XM_006724361 /// XM_006724362 /// XM_006724363 0006605 // protein targeting // inferred from direct assay /// 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // traceable author statement /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0048075 // positive regulation of eye pigmentation // traceable author statement /// 0050821 // protein stabilization // inferred from physical interaction 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031085 // BLOC-3 complex // inferred from physical interaction /// 0042470 // melanosome // inferred from direct assay /// 0042827 // platelet dense granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 54051_at H59033 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H59033:yr40e10.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-207786 /clone_end=5' /gb=H59033 /gi=1011865 /ug=Hs.6700 /len=604 H59033 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 54632_at AI286226 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI286226:qi02e12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1855342 /clone_end=3' /gb=AI286226 /gi=3924459 /ug=Hs.16063 /len=561 AI286226 thyroid adenoma associated THADA 63892 NM_001083953 /// NM_001271643 /// NM_001271644 /// NM_022065 /// NR_073394 /// XM_006712061 /// XM_006712062 /// XM_006712063 /// XM_006712064 /// XM_006712065 /// XM_006712066 /// XM_006712067 /// XM_006712068 /// XM_006712069 /// XR_426993 0005488 // binding // inferred from electronic annotation 54970_at AA868332 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA868332:ak40h05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1408473 /clone_end=3' /gb=AA868332 /gi=2963777 /ug=Hs.77978 /len=481 AA868332 zinc finger, MIZ-type containing 2 ZMIZ2 83637 NM_031449 /// NM_174929 /// XM_005249866 /// XM_005249867 /// XM_005249868 /// XM_005249869 /// XM_005249870 /// XM_005249871 /// XM_005249872 /// XM_005249873 /// XM_005249874 /// XM_005249875 /// XM_006715787 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043596 // nuclear replication fork // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 55065_at AL120554 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL120554:DKFZp761B169_s1 Homo sapiens cDNA, 3 end /clone=DKFZp761B169 /clone_end=3' /gb=AL120554 /gi=5926453 /ug=Hs.8312 /len=512 AL120554 MAP/microtubule affinity-regulating kinase 4 MARK4 57787 NM_001199867 /// NM_031417 /// XM_006723307 0000082 // G1/S transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001578 // microtubule bundle formation // inferred from expression pattern /// 0006468 // protein phosphorylation // traceable author statement /// 0007399 // nervous system development // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016055 // Wnt signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // non-traceable author statement 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0008017 // microtubule binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043015 // gamma-tubulin binding // inferred from direct assay /// 0043130 // ubiquitin binding // non-traceable author statement /// 0050321 // tau-protein kinase activity // inferred from direct assay 55081_at W46406 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W46406:zc31c10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-323922 /clone_end=3' /gb=W46406 /gi=1331036 /ug=Hs.8535 /len=568 W46406 MICAL-like 1 MICALL1 85377 NM_033386 /// XM_005261791 /// XM_005261792 /// XM_006724345 0006612 // protein targeting to membrane // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032456 // endocytic recycling // inferred from electronic annotation /// 0032458 // slow endocytic recycling // inferred from mutant phenotype /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0097320 // membrane tubulation // inferred from direct assay /// 1990126 // retrograde transport, endosome to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070300 // phosphatidic acid binding // inferred from direct assay 55093_at AA534198 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA534198:nj21a11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-993116 /clone_end=3' /gb=AA534198 /gi=2278214 /ug=Hs.86392 /len=603 AA534198 chondroitin polymerizing factor 2 CHPF2 54480 NM_001284295 /// NM_019015 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation 55583_at AI198543 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI198543:qf49f11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1753389 /clone_end=3' /gb=AI198543 /gi=3751149 /ug=Hs.8982 /len=794 AI198543 dedicator of cytokinesis 6 DOCK6 57572 NM_020812 /// XM_005260000 /// XM_005260001 /// XM_006722802 /// XM_006722803 /// XM_006722804 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation 55616_at AI703342 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI703342:wd93b03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2339117 /clone_end=3' /gb=AI703342 /gi=4991242 /ug=Hs.91668 /len=494 AI703342 post-GPI attachment to proteins 3 PGAP3 93210 NM_001291726 /// NM_001291728 /// NM_001291730 /// NM_001291732 /// NM_001291733 /// NM_033419 0006505 // GPI anchor metabolic process // inferred from mutant phenotype /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from direct assay 0016788 // hydrolase activity, acting on ester bonds // inferred from mutant phenotype 55662_at H27225 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H27225:yl63c09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-162928 /clone_end=5' /gb=H27225 /gi=897215 /ug=Hs.9444 /len=508 H27225 chromosome 10 open reading frame 76 C10orf76 79591 NM_024541 /// XM_006717969 /// XR_246104 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 55692_at W22924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W22924:75H3 Homo sapiens cDNA /clone=(not-directional) /gb=W22924 /gi=1299757 /ug=Hs.96560 /len=792 W22924 engulfment and cell motility 2 ELMO2 63916 NM_022086 /// NM_133171 /// NM_182764 /// XM_005260496 /// XM_005260497 /// XM_005260498 /// XM_005260499 /// XM_005260500 /// XM_005260501 /// XM_005260502 /// XM_006723854 /// XM_006723855 0006909 // phagocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction 55705_at W07773 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W07773:zb03g04.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-301014 /clone_end=5' /gb=W07773 /gi=1281785 /ug=Hs.9739 /len=533 W07773 R3H domain containing 4 R3HDM4 91300 NM_138774 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 55872_at AI493119 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI493119:qz49h07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2030269 /clone_end=3' /gb=AI493119 /gi=4394122 /ug=Hs.158654 /len=456 AI493119 zinc finger protein 512B ZNF512B 57473 NM_020713 /// XM_005260226 /// XR_430305 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 56197_at AI783924 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI783924:tr30e11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2219852 /clone_end=3' /gb=AI783924 /gi=5325733 /ug=Hs.103382 /len=539 AI783924 phospholipid scramblase 3 /// TMEM256-PLSCR3 readthrough (NMD candidate) PLSCR3 /// TMEM256-PLSCR3 57048 /// 100529211 NM_001201576 /// NM_020360 /// NR_037719 0006915 // apoptotic process // inferred from electronic annotation /// 0017121 // phospholipid scrambling // non-traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0017128 // phospholipid scramblase activity // non-traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 56256_at AA150165 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA150165:zl06h03.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-491573 /clone_end=5' /gb=AA150165 /gi=1721695 /ug=Hs.20102 /len=576 AA150165 SID1 transmembrane family, member 2 SIDT2 51092 NM_001040455 /// NM_015996 0016246 // RNA interference // inferred from electronic annotation /// 0033227 // dsRNA transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0051033 // RNA transmembrane transporter activity // inferred from electronic annotation 564_at M69013 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank M69013 /FEATURE= /DEFINITION=HUMGTPBRPA Human guanine nucleotide-binding regulatory protein (G-y-alpha) mRNA, complete cds M69013 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 56748_at X90539 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. X90539:HSGT483 Homo sapiens cDNA /clone=GT-483 /gb=X90539 /gi=1296640 /ug=Hs.37680 /len=722 X90539 tripartite motif containing 10 TRIM10 10107 NM_006778 /// NM_052828 0030218 // erythrocyte differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 56821_at AI963454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI963454:wt63e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2512156 /clone_end=3' /gb=AI963454 /gi=5756167 /ug=Hs.10499 /len=750 AI963454 solute carrier family 38, member 7 SLC38A7 55238 NM_018231 /// XM_006721229 /// XR_429722 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from sequence or structural similarity /// 0006865 // amino acid transport // inferred from electronic annotation /// 0006867 // asparagine transport // inferred from electronic annotation /// 0006868 // glutamine transport // inferred from electronic annotation /// 0015803 // branched-chain amino acid transport // inferred from electronic annotation /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0015808 // L-alanine transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015817 // histidine transport // inferred from electronic annotation /// 0015821 // methionine transport // inferred from electronic annotation /// 0015825 // L-serine transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from sequence or structural similarity 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity 0005290 // L-histidine transmembrane transporter activity // inferred from electronic annotation /// 0005313 // L-glutamate transmembrane transporter activity // inferred from electronic annotation /// 0015179 // L-amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015180 // L-alanine transmembrane transporter activity // inferred from electronic annotation /// 0015182 // L-asparagine transmembrane transporter activity // inferred from electronic annotation /// 0015183 // L-aspartate transmembrane transporter activity // inferred from electronic annotation /// 0015186 // L-glutamine transmembrane transporter activity // inferred from sequence or structural similarity /// 0015190 // L-leucine transmembrane transporter activity // inferred from electronic annotation /// 0015191 // L-methionine transmembrane transporter activity // inferred from electronic annotation /// 0015194 // L-serine transmembrane transporter activity // inferred from electronic annotation 56829_at H61826 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H61826:yu41g09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-236416 /clone_end=5' /gb=H61826 /gi=1014658 /ug=Hs.105598 /len=477 H61826 trafficking protein particle complex 9 TRAPPC9 83696 NM_001160372 /// NM_031466 /// XM_005251077 /// XM_006716664 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 56919_at AI806628 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI806628:wf14g08.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2350622 /clone_end=3' /gb=AI806628 /gi=5393194 /ug=Hs.109778 /len=557 AI806628 WD repeat domain 48 WDR48 57599 NM_020839 /// XM_005265346 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 57082_at AA169780 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA169780:zp21a04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-610062 /clone_end=3' /gb=AA169780 /gi=1748115 /ug=Hs.184482 /len=560 AA169780 low density lipoprotein receptor adaptor protein 1 LDLRAP1 26119 NM_015627 /// XM_006710558 /// XM_006710559 /// XM_006710560 /// XM_006710561 /// XM_006710562 /// XR_426598 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // non-traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from direct assay /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0042982 // amyloid precursor protein metabolic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090118 // receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport // inferred from mutant phenotype /// 0090205 // positive regulation of cholesterol metabolic process // inferred by curator 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0030121 // AP-1 adaptor complex // inferred from direct assay /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0001784 // phosphotyrosine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from mutant phenotype /// 0030276 // clathrin binding // inferred from direct assay /// 0035591 // signaling adaptor activity // inferred from direct assay /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction 57163_at H93026 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. H93026:yv06a08.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-241910 /clone_end=3' /gb=H93026 /gi=1099354 /ug=Hs.25597 /len=600 H93026 ELOVL fatty acid elongase 1 /// microRNA 6734 ELOVL1 /// MIR6734 64834 /// 102466723 NM_001256399 /// NM_001256401 /// NM_001256402 /// NM_022821 /// NR_046117 /// NR_106792 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030148 // sphingolipid biosynthetic process // inferred from mutant phenotype /// 0034625 // fatty acid elongation, monounsaturated fatty acid // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042761 // very long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0009922 // fatty acid elongase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 57516_at AA746290 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA746290:oa56b11.r1 Homo sapiens cDNA /clone=IMAGE-1308957 /gb=AA746290 /gi=2786276 /ug=Hs.11765 /len=740 AA746290 zinc finger protein 764 ZNF764 92595 NM_001172679 /// NM_033410 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 57532_at AW016304 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW016304:UI-H-BI0p-abl-h-10-0-UI.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-2712427 /clone_end=3' /gb=AW016304 /gi=5865061 /ug=Hs.118640 /len=591 AW016304 dishevelled segment polarity protein 2 DVL2 1856 NM_004422 /// XM_005256502 /// XM_006721469 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // not recorded /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from genetic interaction /// 0021535 // cell migration in hindbrain // not recorded /// 0022007 // convergent extension involved in neural plate elongation // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035282 // segmentation // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0044340 // canonical Wnt signaling pathway involved in regulation of cell proliferation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005938 // cell cortex // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // not recorded /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0045177 // apical part of cell // not recorded /// 0045334 // clathrin-coated endocytic vesicle // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from electronic annotation 57539_at AA535065 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA535065:nf84a09.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-926584 /clone_end=3' /gb=AA535065 /gi=2279318 /ug=Hs.11900 /len=510 AA535065 Lck interacting transmembrane adaptor 1 /// zinc finger, CCCH-type with G patch domain LIME1 /// ZGPAT 54923 /// 84619 NM_001083113 /// NM_001195653 /// NM_001195654 /// NM_017806 /// NM_032527 /// NM_181484 /// NM_181485 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 57540_at AI823980 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI823980:wj29b03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2404205 /clone_end=3' /gb=AI823980 /gi=5444651 /ug=Hs.11916 /len=620 AI823980 ribokinase RBKS 64080 NM_001287580 /// NM_022128 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006014 // D-ribose metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019303 // D-ribose catabolic process // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004747 // ribokinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation 57588_at R62432 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R62432:yg52e11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-36023 /clone_end=3' /gb=R62432 /gi=834311 /ug=Hs.12321 /len=487 R62432 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 SLC24A3 57419 NM_020689 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008273 // calcium, potassium:sodium antiporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 57703_at N32782 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N32782:yw91g03.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-259636 /clone_end=3' /gb=N32782 /gi=1153181 /ug=Hs.13138 /len=698 N32782 SUMO1/sentrin specific peptidase 5 SENP5 205564 NM_152699 /// XM_005269310 /// XM_005269311 /// XM_005269312 0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 57715_at W72694 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W72694:zd68f10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-345835 /clone_end=3' /gb=W72694 /gi=1382514 /ug=Hs.851 /len=628 W72694 calcium homeostasis modulator 2 CALHM2 51063 NM_015916 /// NR_024552 /// NR_046344 /// XM_006717877 /// XM_006717878 /// XM_006717879 /// XM_006717880 /// XM_006717881 /// XM_006717882 /// XM_006717883 /// XM_006717884 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 57739_at AI949010 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI949010:wq36a07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2473332 /clone_end=3' /gb=AI949010 /gi=5741320 /ug=Hs.104036 /len=457 AI949010 DND microRNA-mediated repression inhibitor 1 DND1 373863 NM_194249 0006364 // rRNA processing // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0060965 // negative regulation of gene silencing by miRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from direct assay 58308_at R71157 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R71157:yi53g05.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-143000 /clone_end=5' /gb=R71157 /gi=844674 /ug=Hs.15921 /len=543 R71157 tripartite motif containing 62 TRIM62 55223 NM_018207 /// XM_006710736 /// XM_006710737 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from mutant phenotype /// 0046596 // regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 1902186 // regulation of viral release from host cell // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 58367_s_at AA429615 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA429615:zw74g05.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-781976 /clone_end=5' /gb=AA429615 /gi=2112716 /ug=Hs.98593 /len=499 AA429615 zinc finger protein 419 ZNF419 79744 NM_001098491 /// NM_001098492 /// NM_001098493 /// NM_001098494 /// NM_001098495 /// NM_001098496 /// NM_001291743 /// NM_001291744 /// NM_001291745 /// NM_024691 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 58696_at AL039469 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL039469:DKFZp434P0110_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434P0110 /clone_end=3' /gb=AL039469 /gi=5408517 /ug=Hs.97574 /len=888 AL039469 exosome component 4 EXOSC4 54512 NM_019037 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006364 // rRNA processing // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0045006 // DNA deamination // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071028 // nuclear mRNA surveillance // inferred from mutant phenotype /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // non-traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035327 // transcriptionally active chromatin // inferred from mutant phenotype 0000175 // 3'-5'-exoribonuclease activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay 58780_s_at R42449 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R42449:yg02a07.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-30831 /clone_end=3' /gb=R42449 /gi=817213 /ug=Hs.235831 /len=431 R42449 Rho guanine nucleotide exchange factor (GEF) 40 ARHGEF40 55701 NM_001278529 /// NM_001278530 /// NM_018071 /// XM_005267844 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 58900_at AW025284 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW025284:wu95h10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-990806 /clone_end=3' /gb=AW025284 /gi=5878814 /ug=Hs.237946 /len=454 AW025284 ubiquitin-conjugating enzyme E2D 4 (putative) UBE2D4 51619 NM_015983 /// XM_005249772 /// XM_006715734 /// XM_006715735 /// XM_006715736 /// XM_006715737 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 58916_at AI672101 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI672101:ty63d10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2283763 /clone_end=3' /gb=AI672101 /gi=4851832 /ug=Hs.17296 /len=554 AI672101 potassium channel tetramerization domain containing 14 /// NDUFC2-KCTD14 readthrough KCTD14 /// NDUFC2-KCTD14 65987 /// 100532726 NM_001203260 /// NM_001203261 /// NM_001203262 /// NM_001282406 /// NM_023930 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation 58994_at AI689402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI689402:tx83e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2276188 /clone_end=3' /gb=AI689402 /gi=4900696 /ug=Hs.181780 /len=383 AI689402 coiled-coil and C2 domain containing 1A CC2D1A 54862 NM_017721 /// XM_005259972 /// XM_005259973 /// XM_005259974 /// XM_005259975 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 59375_at AI825877 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI825877:td19g01.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2076144 /clone_end=3' /gb=AI825877 /gi=5446548 /ug=Hs.115692 /len=567 AI825877 myosin XVB pseudogene MYO15B 80022 NM_001080847 /// NR_003587 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 59433_at N32185 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N32185:yy25d10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-272275 /clone_end=3' /gb=N32185 /gi=1152584 /ug=Hs.120769 /len=600 N32185 uncharacterized LOC102725263 /// zinc finger protein 839 pseudogene LOC102725263 /// LOC389906 389906 /// 102725263 NR_034031 /// XR_426519 59437_at AI830563 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI830563:wj51c03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2406340 /clone_end=3' /gb=AI830563 /gi=5451234 /ug=Hs.120858 /len=556 AI830563 chromosome 9 open reading frame 116 C9orf116 138162 NM_001048265 /// NM_144654 59625_at AI912351 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI912351:tz24d02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2289507 /clone_end=3' /gb=AI912351 /gi=5632206 /ug=Hs.198793 /len=507 AI912351 nucleolar protein 3 (apoptosis repressor with CARD domain) NOL3 8996 NM_001185057 /// NM_001185058 /// NM_001276307 /// NM_001276309 /// NM_001276311 /// NM_001276312 /// NM_001276319 /// NM_003946 /// XM_005256217 /// XM_005256219 /// XM_006721322 /// XM_006721323 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016528 // sarcoplasm // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 59631_at AI247566 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI247566:qh60e06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1849090 /clone_end=3' /gb=AI247566 /gi=3842963 /ug=Hs.20030 /len=723 AI247566 thioredoxin reductase 3 /// thioredoxin reductase 3 neighbor TXNRD3 /// TXNRD3NB 114112 /// 645840 NM_001039783 /// NM_001173513 /// NM_052883 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045454 // cell redox homeostasis // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004791 // thioredoxin-disulfide reductase activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 59644_at AI735391 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI735391:at10e09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2354728 /clone_end=3' /gb=AI735391 /gi=5056915 /ug=Hs.20137 /len=567 AI735391 BMP2 inducible kinase BMP2K 55589 NM_017593 /// NM_198892 /// XM_005263117 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from physical interaction /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // inferred from electronic annotation 59697_at AA582932 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA582932:nn80a11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1090172 /clone_end=3' /gb=AA582932 /gi=2360292 /ug=Hs.21349 /len=614 AA582932 RAB15, member RAS oncogene family RAB15 376267 NM_198686 /// XM_005267597 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 59705_at AA911739 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA911739:oi15f09.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1476617 /clone_end=3' /gb=AA911739 /gi=3051103 /ug=Hs.21421 /len=1049 AA911739 selenocysteine lyase SCLY 51540 NM_016510 0006520 // cellular amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0009000 // selenocysteine lyase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 59999_at W37897 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W37897:zc13e07.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-322212 /clone_end=3' /gb=W37897 /gi=1319491 /ug=Hs.14595 /len=550 W37897 hypoxia inducible factor 1, alpha subunit inhibitor HIF1AN 55662 NM_017902 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0036138 // peptidyl-histidine hydroxylation // inferred from direct assay /// 0042264 // peptidyl-aspartic acid hydroxylation // inferred from direct assay /// 0042265 // peptidyl-asparagine hydroxylation // inferred from direct assay /// 0042265 // peptidyl-asparagine hydroxylation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045746 // negative regulation of Notch signaling pathway // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement /// 2001214 // positive regulation of vasculogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005112 // Notch binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // not recorded /// 0019826 // oxygen sensor activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0036139 // peptidyl-histidine dioxygenase activity // inferred from direct assay /// 0036140 // peptidyl-asparagine 3-dioxygenase activity // inferred from direct assay /// 0036140 // peptidyl-asparagine 3-dioxygenase activity // inferred from mutant phenotype /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071532 // ankyrin repeat binding // inferred from physical interaction 60084_at AI453099 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI453099:tj61e11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2146028 /clone_end=3' /gb=AI453099 /gi=4307988 /ug=Hs.24668 /len=554 AI453099 cylindromatosis (turban tumor syndrome) CYLD 1540 NM_001042355 /// NM_001042412 /// NM_015247 /// XM_005255812 /// XM_006721148 /// XM_006721149 /// XM_006721150 /// XM_006721151 /// XM_006721152 /// XR_429714 0002181 // cytoplasmic translation // not recorded /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0070266 // necroptotic process // not recorded /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001242 // regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0061578 // Lys63-specific deubiquitinase activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction 60471_at AA625133 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA625133:af70b02.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-1047339 /clone_end=5' /gb=AA625133 /gi=2537518 /ug=Hs.180040 /len=494 AA625133 Ras and Rab interactor 3 RIN3 79890 NM_024832 0006897 // endocytosis // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from mutant phenotype /// 0032851 // positive regulation of Rab GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0017137 // Rab GTPase binding // inferred from direct assay 60474_at AA469071 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA469071:ne17f11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-881517 /clone_end=3' /gb=AA469071 /gi=2195605 /ug=Hs.180479 /len=758 AA469071 fermitin family member 1 FERMT1 55612 NM_017671 0007155 // cell adhesion // inferred from direct assay /// 0043616 // keratinocyte proliferation // inferred from direct assay /// 0051546 // keratinocyte migration // inferred from direct assay /// 0090162 // establishment of epithelial cell polarity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031941 // filamentous actin // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 60528_at N71116 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N71116:za87h11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-299589 /clone_end=3' /gb=N71116 /gi=1227696 /ug=Hs.198161 /len=472 N71116 JMJD7-PLA2G4B readthrough /// phospholipase A2, group IVB (cytosolic) JMJD7-PLA2G4B /// PLA2G4B 8681 /// 100137049 NM_001114633 /// NM_001198588 /// NM_005090 /// NR_015346 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007567 // parturition // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // non-traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046475 // glycerophospholipid catabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004620 // phospholipase activity // inferred from electronic annotation /// 0004622 // lysophospholipase activity // non-traceable author statement /// 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // inferred from direct assay 60794_f_at AI400621 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI400621:tg49g02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2112146 /clone_end=3' /gb=AI400621 /gi=4243708 /ug=Hs.213640 /len=529 AI400621 zinc finger protein 814 ZNF814 730051 NM_001144989 0006355 // regulation of transcription, DNA-templated // not recorded 0005622 // intracellular // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 60815_at AA601208 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA601208:no14c12.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1100662 /clone_end=3' /gb=AA601208 /gi=2434833 /ug=Hs.220255 /len=488 AA601208 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene POLR2J4 84820 NM_032734 /// NR_003655 61297_at AL037338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL037338:DKFZp564F1071_s1 Homo sapiens cDNA, 3 end /clone=DKFZp564F1071 /clone_end=3' /gb=AL037338 /gi=5928096 /ug=Hs.239186 /len=682 AL037338 CASK interacting protein 2 CASKIN2 57513 NM_001142643 /// NM_020753 0005737 // cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 61732_r_at AI610355 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI610355:tp18g08.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2188190 /clone_end=3' /gb=AI610355 /gi=4619522 /ug=Hs.39328 /len=463 AI610355 intraflagellar transport 74 homolog (Chlamydomonas) IFT74 80173 NM_001099222 /// NM_001099223 /// NM_001099224 /// NM_025103 0030030 // cell projection organization // inferred from electronic annotation /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // not recorded /// 0005929 // cilium // not recorded /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // not recorded /// 0030992 // intraciliary transport particle B // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from direct assay 61734_at AI797684 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI797684:we90d02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2348355 /clone_end=3' /gb=AI797684 /gi=5363156 /ug=Hs.39619 /len=708 AI797684 reticulocalbin 3, EF-hand calcium binding domain RCN3 57333 NM_020650 /// XM_005259089 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 61874_at AL042496 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL042496:DKFZp434G1921_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434G1921 /clone_end=3' /gb=AL042496 /gi=5421955 /ug=Hs.119285 /len=716 AL042496 calcium channel flower domain containing 1 CACFD1 11094 NM_001135775 /// NM_001242369 /// NM_001242370 /// NM_017586 0048488 // synaptic vesicle endocytosis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from electronic annotation 0005262 // calcium channel activity // inferred from electronic annotation 62212_at W37846 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W37846:zc13d09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-322193 /clone_end=5' /gb=W37846 /gi=1319597 /ug=Hs.55608 /len=598 W37846 chromosome 1 open reading frame 50 /// uncharacterized LOC100129924 C1orf50 /// LOC100129924 79078 /// 100129924 NM_001242750 /// NM_024097 /// NR_040733 0003824 // catalytic activity // inferred from electronic annotation 62987_r_at AI675178 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI675178:tm80g06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2164474 /clone_end=3' /gb=AI675178 /gi=4875658 /ug=Hs.90207 /len=462 AI675178 calcium channel, voltage-dependent, gamma subunit 4 CACNG4 27092 NM_014405 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051899 // membrane depolarization // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2000311 // regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005245 // voltage-gated calcium channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation 63009_at AI188402 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI188402:qd08e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1723132 /clone_end=3' /gb=AI188402 /gi=3739611 /ug=Hs.93391 /len=506 AI188402 SHQ1, H/ACA ribonucleoprotein assembly factor SHQ1 55164 NM_018130 0022618 // ribonucleoprotein complex assembly // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 2000233 // negative regulation of rRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 632_at L40027 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database L40027 /FEATURE=mRNA /DEFINITION=HUMGLYSYN Homo sapiens glycogen synthase kinase 3 mRNA, complete cds L40027 glycogen synthase kinase 3 alpha GSK3A 2931 NM_019884 0003073 // regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010905 // negative regulation of UDP-glucose catabolic process // inferred by curator /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0036016 // cellular response to interleukin-3 // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // non-traceable author statement /// 0045823 // positive regulation of heart contraction // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051348 // negative regulation of transferase activity // inferred from mutant phenotype /// 0061052 // negative regulation of cell growth involved in cardiac muscle cell development // inferred from sequence or structural similarity /// 0071879 // positive regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2000077 // negative regulation of type B pancreatic cell development // traceable author statement /// 2000466 // negative regulation of glycogen (starch) synthase activity // traceable author statement /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement /// 0030877 // beta-catenin destruction complex // non-traceable author statement /// 0030877 // beta-catenin destruction complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0050321 // tau-protein kinase activity // traceable author statement 63305_at D81792 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. D81792:HUM408A08B Homo sapiens cDNA, 5 end /clone=GEN-408A08 /clone_end=5' /gb=D81792 /gi=1180423 /ug=Hs.10043 /len=516 D81792 PBX/knotted 1 homeobox 2 PKNOX2 63876 NM_022062 /// XM_005271642 /// XM_005271643 /// XM_006718894 /// XM_006718895 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 635_s_at L42374 Homo sapiens Oct 6, 2014 Exemplar sequence Affymetrix Proprietary Database L42374 /FEATURE=mRNA /DEFINITION=HUMPP2ABA Homo sapiens protein phosphatase 2A B56-beta (PP2A) mRNA, complete cds L42374 protein phosphatase 2, regulatory subunit B', beta PPP2R5B 5526 NM_006244 /// XM_006718606 /// XM_006718607 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 63825_at AI557319 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI557319:PT2.1_16_F08.r Homo sapiens cDNA, 3 end /clone_end=3' /gb=AI557319 /gi=4489682 /ug=Hs.21921 /len=876 AI557319 abhydrolase domain containing 2 ABHD2 11057 NM_007011 /// NM_152924 /// XM_005254832 /// XM_005254833 0008152 // metabolic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 64064_at AI435089 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI435089:th95b11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2126397 /clone_end=3' /gb=AI435089 /gi=4300737 /ug=Hs.26194 /len=891 AI435089 GIMAP1-GIMAP5 readthrough /// GTPase, IMAP family member 5 GIMAP1-GIMAP5 /// GIMAP5 55340 /// 100527949 NM_001199577 /// NM_018384 0001659 // temperature homeostasis // inferred from electronic annotation /// 0002729 // positive regulation of natural killer cell cytokine production // inferred from electronic annotation /// 0002925 // positive regulation of humoral immune response mediated by circulating immunoglobulin // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from electronic annotation /// 0032831 // positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050995 // negative regulation of lipid catabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 64371_at AI978718 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI978718:wr58g05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2491928 /clone_end=3' /gb=AI978718 /gi=5803748 /ug=Hs.237936 /len=515 AI978718 SURP and G patch domain containing 2 SUGP2 10147 NM_001017392 /// NM_014884 /// XR_430120 /// XR_430121 /// XR_430122 /// XR_430123 /// XR_430124 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 64408_s_at AW025529 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW025529:wu97d12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-990954 /clone_end=3' /gb=AW025529 /gi=5879059 /ug=Hs.47536 /len=661 AW025529 calmodulin-like 4 CALML4 91860 NM_001031733 /// NM_001286694 /// NM_001286695 /// NM_033429 /// NR_104583 0005509 // calcium ion binding // inferred from electronic annotation 64418_at AI472320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI472320:tj87c02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2148482 /clone_end=3' /gb=AI472320 /gi=4334410 /ug=Hs.48504 /len=548 AI472320 synergin, gamma SYNRG 11276 NM_001163544 /// NM_001163545 /// NM_001163546 /// NM_001163547 /// NM_007247 /// NM_080550 /// NM_198882 /// XM_005256980 /// XM_005256981 /// XM_005256982 /// XM_005256983 /// XM_005256985 /// XM_005256986 /// XM_005256988 /// XM_006721652 /// XM_006721653 /// XM_006721654 /// XM_006721655 /// XM_006725301 /// XM_006725302 /// XM_006725303 /// XM_006725304 /// XM_006725305 /// XM_006725306 /// XM_006725307 /// XM_006725308 /// XM_006725309 /// XM_006725310 /// XM_006725311 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation 64432_at W05463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W05463:za87a12.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-299518 /clone_end=5' /gb=W05463 /gi=1278185 /ug=Hs.52166 /len=564 W05463 MAPKAPK5 antisense RNA 1 MAPKAPK5-AS1 51275 NM_016534 /// NR_015404 64438_at W19668 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W19668:zb36a01.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-305640 /clone_end=5' /gb=W19668 /gi=1295587 /ug=Hs.54558 /len=574 W19668 2-oxoglutarate and iron-dependent oxygenase domain containing 3 OGFOD3 79701 NM_024648 /// NM_175902 /// NR_033265 /// XR_430034 0055114 // oxidation-reduction process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 64440_at AI560217 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI560217:tq52d02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2212419 /clone_end=3' /gb=AI560217 /gi=4510558 /ug=Hs.54849 /len=494 AI560217 interleukin 17 receptor C IL17RC 84818 NM_001203263 /// NM_001203264 /// NM_001203265 /// NM_032732 /// NM_153460 /// NM_153461 /// NM_153462 /// NM_153463 /// NR_037807 /// XM_006713346 /// XM_006713347 /// XM_006713348 /// XM_006713349 /// XM_006713350 /// XM_006713351 /// XM_006713352 /// XM_006713353 /// XM_006713354 /// XM_006713355 /// XM_006713356 /// XM_006713357 /// XM_006713358 /// XM_006713359 /// XM_006713360 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 1900017 // positive regulation of cytokine production involved in inflammatory response // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030368 // interleukin-17 receptor activity // inferred from direct assay 64474_g_at AA203219 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA203219:zx56d02.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-446499 /clone_end=5' /gb=AA203219 /gi=1799058 /ug=Hs.59457 /len=901 AA203219 DGCR8 microprocessor complex subunit /// microRNA 1306 DGCR8 /// MIR1306 54487 /// 100302197 NM_001190326 /// NM_022720 /// NR_031706 /// XM_006724268 0010467 // gene expression // traceable author statement /// 0031053 // primary miRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 64486_at AI341234 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI341234:qx90b09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2009753 /clone_end=3' /gb=AI341234 /gi=4078161 /ug=Hs.6191 /len=904 AI341234 coronin, actin binding protein, 1B CORO1B 57175 NM_001018070 /// NM_020441 0016477 // cell migration // inferred from direct assay /// 0030036 // actin cytoskeleton organization // not recorded /// 0031529 // ruffle organization // inferred from direct assay /// 0034316 // negative regulation of Arp2/3 complex-mediated actin nucleation // inferred from direct assay /// 0035767 // endothelial cell chemotaxis // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay /// 0090135 // actin filament branching // inferred from direct assay /// 1902463 // protein localization to cell leading edge // inferred from direct assay /// 2000394 // positive regulation of lamellipodium morphogenesis // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0030027 // lamellipodium // inferred from direct assay /// 0031252 // cell leading edge // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0051015 // actin filament binding // not recorded /// 0051015 // actin filament binding // inferred from direct assay /// 0071933 // Arp2/3 complex binding // inferred from direct assay 64488_at AW003091 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW003091:wr03d04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2480455 /clone_end=3' /gb=AW003091 /gi=5849929 /ug=Hs.6217 /len=613 AW003091 immunity-related GTPase family, Q IRGQ 126298 NM_001007561 /// XM_005258515 /// XM_005258516 64883_at AI744083 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI744083:wc36b04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2317231 /clone_end=3' /gb=AI744083 /gi=5112371 /ug=Hs.65406 /len=608 AI744083 motile sperm domain containing 2 MOSPD2 158747 NM_001177475 /// NM_152581 /// XM_005274451 /// XM_006724467 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 64899_at AA209463 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA209463:zq84h11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-648357 /clone_end=3' /gb=AA209463 /gi=1807425 /ug=Hs.6846 /len=533 AA209463 lipid phosphate phosphatase-related protein type 2 LPPR2 64748 NM_001170635 /// NM_022737 /// XM_005260017 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008195 // phosphatidate phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 64900_at AA401703 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA401703:zt60f09.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-726761 /clone_end=5' /gb=AA401703 /gi=2057294 /ug=Hs.6853 /len=580 AA401703 transmembrane protein 231 TMEM231 79583 NM_001077416 /// NM_001077418 /// NR_074083 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from sequence or structural similarity /// 0036038 // TCTN-B9D complex // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 64942_at AI937160 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI937160:wp73h02.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2467443 /clone_end=3' /gb=AI937160 /gi=5676030 /ug=Hs.7967 /len=552 AI937160 G protein-coupled receptor 153 GPR153 387509 NM_207370 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 65086_at Z78349 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. Z78349:HSZ78349 Homo sapiens cDNA /clone=2.91-(CEPH) /gb=Z78349 /gi=1495122 /ug=Hs.239764 /len=924 Z78349 Yip1 domain family, member 2 YIPF2 78992 NM_024029 /// XM_005260069 /// XM_005260070 /// XM_005260071 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 65133_i_at AI862454 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI862454:td16f08.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2075847 /clone_end=3' /gb=AI862454 /gi=5526561 /ug=Hs.118282 /len=857 AI862454 INO80 complex subunit B /// INO80B-WBP1 readthrough (NMD candidate) INO80B /// INO80B-WBP1 83444 /// 100532735 NM_031288 /// NR_037849 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 65438_at AA195124 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA195124:zr35c05.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-665384 /clone_end=5' /gb=AA195124 /gi=1784835 /ug=Hs.14449 /len=799 AA195124 TBC/LysM-associated domain containing 1 TLDC1 57707 NM_020947 /// XM_005256074 /// XM_005256075 /// XM_005256077 /// XM_006721240 0005765 // lysosomal membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 65472_at AI161338 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI161338:qb80a04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1706382 /clone_end=3' /gb=AI161338 /gi=3694582 /ug=Hs.16959 /len=606 AI161338 chromosome 2 open reading frame 68 C2orf68 388969 NM_001013649 /// XM_005264304 /// XM_005264305 /// XM_005264306 65493_at AA555088 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA555088:nj40c05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-994952 /clone_end=3' /gb=AA555088 /gi=2325627 /ug=Hs.17230 /len=638 AA555088 HEAT repeat containing 6 HEATR6 63897 NM_022070 /// XM_005257570 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 65517_at AA910946 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA910946:ok85g06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1520794 /clone_end=3' /gb=AA910946 /gi=3050236 /ug=Hs.18894 /len=982 AA910946 adaptor-related protein complex 1, mu 2 subunit AP1M2 10053 NM_005498 /// XM_005259701 0006605 // protein targeting // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006903 // vesicle targeting // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation 65521_at W74577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W74577:zd56g04.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-344694 /clone_end=5' /gb=W74577 /gi=1384196 /ug=Hs.19196 /len=586 W74577 ubiquitin-conjugating enzyme E2D 4 (putative) UBE2D4 51619 NM_015983 /// XM_005249772 /// XM_006715734 /// XM_006715735 /// XM_006715736 /// XM_006715737 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 65585_at AA527515 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA527515:ng41h06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-937403 /clone_end=3' /gb=AA527515 /gi=2269584 /ug=Hs.238570 /len=587 AA527515 family with sequence similarity 86, member B1 /// family with sequence similarity 86, member B2 /// family with sequence similarity 86, member C1 /// family with sequence similarity 86, member D, pseudogene /// family with sequence similarity 86, member A pseudogene FAM86B1 /// FAM86B2 /// FAM86C1 /// FAM86DP /// FAM86FP 55199 /// 85002 /// 653113 /// 653333 /// 692099 NM_001083537 /// NM_001099653 /// NM_001137610 /// NM_018172 /// NM_152563 /// NR_003494 /// NR_024241 /// NR_024254 /// XM_005273603 /// XM_005273604 /// XM_005273605 /// XM_005273606 /// XM_005273607 /// XM_006716255 /// XM_006716256 /// XM_006716257 /// XM_006716258 /// XM_006716259 /// XM_006716260 /// XM_006716261 /// XM_006716262 /// XM_006716387 /// XM_006716388 /// XM_006726459 /// XR_247129 /// XR_428289 /// XR_428290 /// XR_428316 65588_at AA827892 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA827892:od08e04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1367358 /clone_end=3' /gb=AA827892 /gi=2900255 /ug=Hs.239018 /len=622 AA827892 small nucleolar RNA host gene 17 (non-protein coding) SNHG17 388796 NR_015366 /// NR_027241 65591_at N64681 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. N64681:yz87g05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-290072 /clone_end=3' /gb=N64681 /gi=1212510 /ug=Hs.239120 /len=606 N64681 WD repeat domain 48 WDR48 57599 NM_020839 /// XM_005265346 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 65630_at AI742455 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI742455:wg43b05.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2367825 /clone_end=3' /gb=AI742455 /gi=5110743 /ug=Hs.28974 /len=489 AI742455 transmembrane protein 80 TMEM80 283232 NM_001042463 /// NM_001042464 /// NM_001276253 /// NM_001276274 /// NM_174940 /// XM_006718206 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 65635_at AL044097 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AL044097:DKFZp434M1928_s1 Homo sapiens cDNA, 3 end /clone=DKFZp434M1928 /clone_end=3' /gb=AL044097 /gi=5432324 /ug=Hs.29288 /len=605 AL044097 endo-beta-N-acetylglucosaminidase ENGASE 64772 NM_001042573 /// NM_022759 /// XM_006722015 /// XM_006722016 /// XM_006722017 /// XM_006722018 /// XM_006722019 /// XR_429918 /// XR_429919 /// XR_429920 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0033925 // mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity // inferred from electronic annotation 65718_at AI655903 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI655903:tt41c07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2243340 /clone_end=3' /gb=AI655903 /gi=4739882 /ug=Hs.17270 /len=548 AI655903 G protein-coupled receptor 124 GPR124 25960 NM_032777 /// XM_005273471 /// XM_006716325 0001525 // angiogenesis // inferred from electronic annotation /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0010595 // positive regulation of endothelial cell migration // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0050920 // regulation of chemotaxis // inferred from sequence or structural similarity /// 0090210 // regulation of establishment of blood-brain barrier // inferred from electronic annotation /// 1900747 // negative regulation of vascular endothelial growth factor signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 65770_at AI186666 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI186666:qe82a10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1745466 /clone_end=3' /gb=AI186666 /gi=3737304 /ug=Hs.21497 /len=512 AI186666 ras homolog family member T2 RHOT2 89941 NM_138769 /// XM_005255660 /// XM_005255661 /// XM_005255662 /// XM_005255663 /// XM_005255664 /// XM_006720970 /// XM_006720971 /// XM_006720972 /// XM_006720973 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019725 // cellular homeostasis // inferred from mutant phenotype /// 0047497 // mitochondrion transport along microtubule // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097345 // mitochondrial outer membrane permeabilization // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 65884_at AA631254 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA631254:nq81c12.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1158742 /clone_end=3' /gb=AA631254 /gi=2553865 /ug=Hs.4814 /len=876 AA631254 mannosidase, alpha, class 1B, member 1 MAN1B1 11253 NM_016219 /// NR_045720 /// NR_045721 /// XM_006716945 /// XM_006716946 0006457 // protein folding // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0044322 // endoplasmic reticulum quality control compartment // traceable author statement 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from direct assay /// 0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 66053_at AI738452 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI738452:wi32a07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2391924 /clone_end=3' /gb=AI738452 /gi=5100433 /ug=Hs.203286 /len=533 AI738452 heterogeneous nuclear ribonucleoprotein U-like 2 /// HNRNPUL2-BSCL2 readthrough HNRNPUL2 /// HNRNPUL2-BSCL2 221092 /// 100534595 NM_001079559 /// NR_037946 0005634 // nucleus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 71933_at AI218134 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI218134:qh27f10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1845931 /clone_end=3' /gb=AI218134 /gi=3797949 /ug=Hs.220783 /len=499 AI218134 wingless-type MMTV integration site family, member 6 WNT6 7475 NM_006522 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009798 // axis specification // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // not recorded /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from mutant phenotype /// 0045165 // cell fate commitment // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060684 // epithelial-mesenchymal cell signaling // inferred from electronic annotation /// 0061303 // cornea development in camera-type eye // inferred from sequence or structural similarity /// 0070172 // positive regulation of tooth mineralization // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0072079 // nephron tubule formation // inferred from electronic annotation /// 0072080 // nephron tubule development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded 74694_s_at AA907940 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA907940:ol24e02.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1524410 /clone_end=3' /gb=AA907940 /gi=3041944 /ug=Hs.234006 /len=404 AA907940 rabaptin, RAB GTPase binding effector protein 2 RABEP2 79874 NM_024816 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 76897_s_at AA628140 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA628140:af97e06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1055746 /clone_end=3' /gb=AA628140 /gi=2540527 /ug=Hs.126089 /len=302 AA628140 FK506 binding protein 15, 133kDa FKBP15 23307 NM_015258 /// XM_006717018 /// XM_006717019 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 77508_r_at AW001436 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW001436:wu31e04.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-990769 /clone_end=3' /gb=AW001436 /gi=5848352 /ug=Hs.170253 /len=471 AW001436 rabaptin, RAB GTPase binding effector protein 2 RABEP2 79874 NM_024816 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation 78047_s_at AW001777 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW001777:ws04f09.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2496233 /clone_end=3' /gb=AW001777 /gi=5848693 /ug=Hs.233641 /len=485 AW001777 MMP24 antisense RNA 1 MMP24-AS1 101410538 NR_102705 /// NR_102706 78330_at AA845577 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA845577:ak04e11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1405004 /clone_end=3' /gb=AA845577 /gi=2933336 /ug=Hs.165983 /len=504 AA845577 zinc finger protein 335 ZNF335 63925 NM_022095 /// XM_005260504 /// XM_005260506 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050671 // positive regulation of lymphocyte proliferation // inferred from mutant phenotype /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 78383_at AI150117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI150117:qf44e06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1752898 /clone_end=3' /gb=AI150117 /gi=3678586 /ug=Hs.121573 /len=482 AI150117 TOPORS antisense RNA 1 TOPORS-AS1 100129250 NR_033991 /// NR_033992 /// NR_102376 /// NR_102377 78495_at R61320 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. R61320:yh07e06.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-42364 /clone_end=3' /gb=R61320 /gi=832015 /ug=Hs.14217 /len=555 R61320 zinc finger family member 783 ZNF783 100289678 NM_001195220 /// XM_005249929 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 79005_at AA504646 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA504646:aa63e11.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-825644 /clone_end=3' /gb=AA504646 /gi=2240806 /ug=Hs.136389 /len=444 AA504646 solute carrier family 35, member E1 SLC35E1 79939 NM_024881 0006810 // transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 81737_at AI424872 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI424872:tg38f10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2111083 /clone_end=3' /gb=AI424872 /gi=4270895 /ug=Hs.159375 /len=443 AI424872 uncharacterized LOC100505915 LOC100505915 100505915 XR_429670 81811_at AI744451 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI744451:wf89d08.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2362767 /clone_end=3' /gb=AI744451 /gi=5112739 /ug=Hs.124620 /len=564 AI744451 823_at U84487 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U84487 /FEATURE= /DEFINITION=HSU84487 Human CX3C chemokine precursor, mRNA, alternatively spliced, complete cds U84487 chemokine (C-X3-C motif) ligand 1 CX3CL1 6376 NM_002996 0006935 // chemotaxis // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // traceable author statement /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0048247 // lymphocyte chemotaxis // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from expression pattern /// 0050902 // leukocyte adhesive activation // traceable author statement /// 0051041 // positive regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // traceable author statement 87100_at AI832249 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI832249:td14g10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2075682 /clone_end=3' /gb=AI832249 /gi=5452920 /ug=Hs.211522 /len=545 AI832249 abhydrolase domain containing 2 ABHD2 11057 NM_007011 /// NM_152924 /// XM_005254832 /// XM_005254833 0008152 // metabolic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation 89476_r_at AA398062 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA398062:zt89e12.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-729550 /clone_end=5' /gb=AA398062 /gi=2053300 /ug=Hs.202608 /len=584 AA398062 aminopeptidase-like 1 NPEPL1 79716 NM_001204872 /// NM_001204873 /// NM_024663 0006508 // proteolysis // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 89948_at AI743331 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI743331:wg91f07.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2372485 /clone_end=3' /gb=AI743331 /gi=5111619 /ug=Hs.122258 /len=532 AI743331 PDX1 C-terminal inhibiting factor 1 PCIF1 63935 NM_022104 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 89977_at AI733019 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI733019:oh64e12.x5 Homo sapiens cDNA, 3 end /clone=IMAGE-1471822 /clone_end=3' /gb=AI733019 /gi=5054132 /ug=Hs.122939 /len=646 AI733019 acyl-CoA synthetase medium-chain family member 5 ACSM5 54988 NM_017888 /// XM_006721055 /// XM_006721056 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047760 // butyrate-CoA ligase activity // inferred from electronic annotation 90265_at AW050627 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AW050627:wz19e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2558524 /clone_end=3' /gb=AW050627 /gi=5912897 /ug=Hs.135183 /len=477 AW050627 ArfGAP with dual PH domains 1 ADAP1 11033 NM_001284308 /// NM_001284309 /// NM_001284310 /// NM_001284311 /// NM_006869 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 90610_at AI654857 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI654857:wb65b10.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2310523 /clone_end=3' /gb=AI654857 /gi=4738836 /ug=Hs.160115 /len=621 AI654857 leucine-rich repeats and calponin homology (CH) domain containing 4 LRCH4 4034 NM_001289934 /// NM_002319 /// XM_005250346 /// XM_005250347 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 91580_at W22117 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. W22117:62H2 Homo sapiens cDNA /clone=(not-directional) /gb=W22117 /gi=1298999 /ug=Hs.36766 /len=801 W22117 leucine-rich repeats and transmembrane domains 1 LRTM1 57408 NM_020678 /// XM_005265337 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 91617_at AI028241 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI028241:ow01b03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1645517 /clone_end=3' /gb=AI028241 /gi=3245550 /ug=Hs.59457 /len=752 AI028241 DGCR8 microprocessor complex subunit /// microRNA 1306 DGCR8 /// MIR1306 54487 /// 100302197 NM_001190326 /// NM_022720 /// NR_031706 /// XM_006724268 0010467 // gene expression // traceable author statement /// 0031053 // primary miRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 91682_at AI571298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI571298:tn44e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2170492 /clone_end=3' /gb=AI571298 /gi=4534672 /ug=Hs.97574 /len=537 AI571298 91684_g_at AI571298 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI571298:tn44e03.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2170492 /clone_end=3' /gb=AI571298 /gi=4534672 /ug=Hs.97574 /len=537 AI571298 exosome component 4 EXOSC4 54512 NM_019037 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 0006364 // rRNA processing // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0045006 // DNA deamination // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0071028 // nuclear mRNA surveillance // inferred from mutant phenotype /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // non-traceable author statement 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0035327 // transcriptionally active chromatin // inferred from mutant phenotype 0000175 // 3'-5'-exoribonuclease activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004532 // exoribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay 91703_at AA149545 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AA149545:zl28g08.r1 Homo sapiens cDNA, 5 end /clone=IMAGE-503294 /clone_end=5' /gb=AA149545 /gi=1720346 /ug=Hs.131885 /len=582 AA149545 EH domain binding protein 1-like 1 EHBP1L1 254102 NM_001099409 /// XM_005273867 /// XM_005273868 /// XM_005273869 /// XM_005273870 /// XM_006718486 /// XM_006718487 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 91816_f_at C18318 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. C18318:C18318 Homo sapiens cDNA, 5 end /clone=GEN-560E03 /clone_end=5' /gb=C18318 /gi=1579920 /ug=Hs.123469 /len=519 C18318 mex-3 RNA binding family member D MEX3D 399664 NM_001174118 /// NM_203304 /// XM_006726771 0010609 // mRNA localization resulting in posttranscriptional regulation of gene expression // non-traceable author statement /// 0061157 // mRNA destabilization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 91826_at AI219073 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI219073:qg16e08.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1759718 /clone_end=3' /gb=AI219073 /gi=3801276 /ug=Hs.126062 /len=555 AI219073 EPS8-like 1 EPS8L1 54869 NM_017729 /// NM_133180 /// NM_139204 /// XM_005259020 0007266 // Rho protein signal transduction // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0035023 // regulation of Rho protein signal transduction // inferred from direct assay /// 1900029 // positive regulation of ruffle assembly // inferred from genetic interaction 0005737 // cytoplasm // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0042608 // T cell receptor binding // inferred from physical interaction 91920_at AI205180 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI205180:ap13b11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1955229 /clone_end=3' /gb=AI205180 /gi=3758242 /ug=Hs.153360 /len=532 AI205180 brevican BCAN 63827 NM_021948 /// NM_198427 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 91952_at AI363375 Homo sapiens Oct 6, 2014 Consensus sequence GenBank Cluster Incl. AI363375:qy55f12.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2015951 /clone_end=3' /gb=AI363375 /gi=4114996 /ug=Hs.179801 /len=470 AI363375 DDB1 and CUL4 associated factor 15 DCAF15 90379 NM_138353 0016567 // protein ubiquitination // inferred from electronic annotation AFFX-BioB-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2755-3052 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioB-3 AFFX-BioB-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2032-2305 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioB-5 AFFX-BioB-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2482-2739 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioB-M AFFX-BioC-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioC /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 4626-4878 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioC-3 AFFX-BioC-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioC /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 4218-4566 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioC-5 AFFX-BioDn-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioD /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 5286-5570 of gb:J04423.1, not 100% identical /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioDn-3 AFFX-BioDn-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioD /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 4980-5256 of gb:J04423.1, not 100% identical /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-BioDn-5 AFFX-CreX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database Bacteriophage P1 /GEN=cre /DB_XREF=gb:X03453.1 /NOTE=SIF corresponding to nucleotides 1089-1495 of gb:X03453.1 /DEF=Bacteriophage P1 cre gene for recombinase protein. AFFX-CreX-3 AFFX-CreX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database Bacteriophage P1 /GEN=cre /DB_XREF=gb:X03453.1 /NOTE=SIF corresponding to nucleotides 513-1047 of gb:X03453.1 /DEF=Bacteriophage P1 cre gene for recombinase protein. AFFX-CreX-5 AFFX-DapX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=jojG /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 2684-3130 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-DapX-3 AFFX-DapX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=dapB /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 1428-1926 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-DapX-5 AFFX-DapX-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=dapB, jojF /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 2020-2580 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-DapX-M AFFX-HSAC07/X00351_3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=beta-actin /DB_XREF=gb:X00351.1 /NOTE=SIF corresponding to nucleotides 1201-1738 of gb:X00351.1, not 100% identical /DEF=Human mRNA for beta-actin. AFFX-HSAC07/X00351_3 actin, beta ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction AFFX-HSAC07/X00351_5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=beta-actin /DB_XREF=gb:X00351.1 /NOTE=SIF corresponding to nucleotides 50-584 of gb:X00351.1 /DEF=Human mRNA for beta-actin. AFFX-HSAC07/X00351_5 actin, beta ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction AFFX-HSAC07/X00351_M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=beta-actin /DB_XREF=gb:X00351.1 /NOTE=SIF corresponding to nucleotides 645-1173 of gb:X00351.1 /DEF=Human mRNA for beta-actin. AFFX-HSAC07/X00351_M actin, beta ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction AFFX-HUMGAPDH/M33197_3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=GAPD /DB_XREF=gb:M33197.1 /NOTE=SIF corresponding to nucleotides 908-1256 of gb:M33197.1 /DEF=Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA, complete cds. AFFX-HUMGAPDH/M33197_3 glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation AFFX-HUMGAPDH/M33197_5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=GAPD /DB_XREF=gb:M33197.1 /NOTE=SIF corresponding to nucleotides 87-387 of gb:M33197.1 /DEF=Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA, complete cds. AFFX-HUMGAPDH/M33197_5 glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation AFFX-HUMGAPDH/M33197_M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=GAPD /DB_XREF=gb:M33197.1 /NOTE=SIF corresponding to nucleotides 493-832 of gb:M33197.1 /DEF=Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA, complete cds. AFFX-HUMGAPDH/M33197_M glyceraldehyde-3-phosphate dehydrogenase GAPDH 2597 NM_001256799 /// NM_001289745 /// NM_001289746 /// NM_002046 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0035606 // peptidyl-cysteine S-trans-nitrosylation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // inferred from sequence or structural similarity /// 0004365 // glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035605 // peptidyl-cysteine S-nitrosylase activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation AFFX-HUMISGF3A/M97935_3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=ISGF-3 /DB_XREF=gb:M97935.1 /NOTE=SIF corresponding to nucleotides 3413-3914 of gb:M97935.1 /DEF=Homo sapiens transcription factor ISGF-3 mRNA, complete cds. AFFX-HUMISGF3A/M97935_3 signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation AFFX-HUMISGF3A/M97935_5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=ISGF-3 /DB_XREF=gb:M97935.1 /NOTE=SIF corresponding to nucleotides 241-796 of gb:M97935.1 /DEF=Homo sapiens transcription factor ISGF-3 mRNA, complete cds. AFFX-HUMISGF3A/M97935_5 signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation AFFX-HUMISGF3A/M97935_MA_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=ISGF-3 /DB_XREF=gb:M97935.1 /NOTE=SIF corresponding to nucleotides 1397-1820 of gb:M97935.1 /DEF=Homo sapiens transcription factor ISGF-3 mRNA, complete cds. AFFX-HUMISGF3A/M97935_MA signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation AFFX-HUMISGF3A/M97935_MB_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=ISGF-3 /DB_XREF=gb:M97935.1 /NOTE=SIF corresponding to nucleotides 2292-2880 of gb:M97935.1 /DEF=Homo sapiens transcription factor ISGF-3 mRNA, complete cds. AFFX-HUMISGF3A/M97935_MB signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation AFFX-HUMRGE/M10098_3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=18S rRNA /DB_XREF=gb:M10098.1 /NOTE=SIF corresponding to nucleotides 1322-1910 of gb:M10098.1 /DEF=Human 18S rRNA gene, complete. AFFX-HUMRGE/M10098_3 AFFX-HUMRGE/M10098_5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=18S rRNA /DB_XREF=gb:M10098.1 /NOTE=SIF corresponding to nucleotides 115-595 of gb:M10098.1 /DEF=Human 18S rRNA gene, complete. AFFX-HUMRGE/M10098_5 AFFX-HUMRGE/M10098_M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=18S rRNA /DB_XREF=gb:M10098.1 /NOTE=SIF corresponding to nucleotides 688-1219 of gb:M10098.1 /DEF=Human 18S rRNA gene, complete. AFFX-HUMRGE/M10098_M AFFX-hum_alu_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=Alu-Sq /DB_XREF=gb:U14573.1 /NOTE=SIF corresponding to nucleotides 11-278 of gb:U14573.1, not 100% identical /DEF=Human Alu-Sq subfamily consensus sequence. AFFX-hum_alu AFFX-LysX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 1061-1343 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-LysX-3 AFFX-LysX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 387-658 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-LysX-5 AFFX-LysX-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 720-990 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-LysX-M AFFX-M27830_3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=28S rRNA /DB_XREF=gb:M27830.1 /NOTE=SIF corresponding to nucleotides 1800-1891 of gb:M27830.1 /DEF=Human 28S ribosomal RNA gene, complete cds. AFFX-M27830_3 AFFX-M27830_5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=28S rRNA /DB_XREF=gb:M27830.1 /NOTE=SIF corresponding to nucleotides 75-171 of gb:M27830.1 /DEF=Human 28S ribosomal RNA gene, complete cds. AFFX-M27830_5 AFFX-M27830_M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database H. sapiens /GEN=28S rRNA /DB_XREF=gb:M27830.1 /NOTE=SIF corresponding to nucleotides 529-1289 of gb:M27830.1 /DEF=Human 28S ribosomal RNA gene, complete cds. AFFX-M27830_M AFFX-PheX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheB /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2885-3326 of gb:M24537.1, not 100% identical /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-PheX-3 AFFX-PheX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheA /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2028-2375 of gb:M24537.1, not 100% identical /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-PheX-5 AFFX-PheX-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheA /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2437-2828 of gb:M24537.1 /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-PheX-M AFFX-r2-Bs-dap-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=jojG /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 2634-3089 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-r2-Bs-dap-3 AFFX-r2-Bs-dap-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=dapB /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 1439-1846 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-r2-Bs-dap-5 AFFX-r2-Bs-dap-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=dapB, jojF /DB_XREF=gb:L38424.1 /NOTE=SIF corresponding to nucleotides 2055-2578 of gb:L38424.1 /DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carboxylase ligase (birA) gene, complete cds; jojC, jojD, jojF, jojG, jojH genes, complete cds's. AFFX-r2-Bs-dap-M AFFX-r2-Bs-lys-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 1008-1263 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-r2-Bs-lys-3 AFFX-r2-Bs-lys-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 411-659 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-r2-Bs-lys-5 AFFX-r2-Bs-lys-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=lys /DB_XREF=gb:X17013.1 /NOTE=SIF corresponding to nucleotides 673-1002 of gb:X17013.1, not 100% identical /DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). AFFX-r2-Bs-lys-M AFFX-r2-Bs-phe-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheB /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2897-3200 of gb:M24537.1, not 100% identical /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-r2-Bs-phe-3 AFFX-r2-Bs-phe-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheA /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2116-2382 of gb:M24537.1 /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-r2-Bs-phe-5 AFFX-r2-Bs-phe-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=pheA /DB_XREF=gb:M24537.1 /NOTE=SIF corresponding to nucleotides 2484-2875 of gb:M24537.1 /DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofunctional prephenate dehydratase (pheA) genes, complete cds. AFFX-r2-Bs-phe-M AFFX-r2-Bs-thr-3_s_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrB /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 1735-2143 of gb:X04603.1 /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase. AFFX-r2-Bs-thr-3 AFFX-r2-Bs-thr-5_s_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrC /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 290-888 of gb:X04603.1 /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase. AFFX-r2-Bs-thr-5 AFFX-r2-Bs-thr-M_s_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrC, thrB /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 1045-1556 of gb:X04603.1 /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase. AFFX-r2-Bs-thr-M AFFX-r2-Ec-bioB-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2772-3004 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioB-3 AFFX-r2-Ec-bioB-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2071-2304 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioB-5 AFFX-r2-Ec-bioB-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioB /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 2393-2682 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioB-M AFFX-r2-Ec-bioC-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioC /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 4608-4883 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioC-3 AFFX-r2-Ec-bioC-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioC /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 4257-4573 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioC-5 AFFX-r2-Ec-bioD-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioD /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 5312-5559 of gb:J04423.1, not 100% identical /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioD-3 AFFX-r2-Ec-bioD-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database E. coli /GEN=bioD /DB_XREF=gb:J04423.1 /NOTE=SIF corresponding to nucleotides 5024-5244 of gb:J04423.1 /DEF=E.coli 7,8-diamino-pelargonic acid (bioA), biotin synthetase (bioB), 7-keto-8-amino-pelargonic acid synthetase (bioF), bioC protein, and dethiobiotin synthetase (bioD), complete cds. AFFX-r2-Ec-bioD-5 AFFX-r2-Hs18SrRNA-3_s_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M10098.1 Human 18S rRNA sequence, length 1969 bases, 3 prime target bases 1293-1938 AFFX-r2-Hs18SrRNA-3 AFFX-r2-Hs18SrRNA-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M10098.1 Human 18S rRNA sequence, length 1969 bases, 5 prime target bases 1-646 AFFX-r2-Hs18SrRNA-5 AFFX-r2-Hs18SrRNA-M_x_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M10098.1 Human 18S rRNA sequence, length 1969 bases, middle target bases 647-1292 AFFX-r2-Hs18SrRNA-M AFFX-r2-Hs28SrRNA-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M11167.1 Human 28S rRNA sequence, length 5025 bases, middle target bases 1666-3330 AFFX-r2-Hs28SrRNA-3 AFFX-r2-Hs28SrRNA-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M11167.1 Human 28S rRNA sequence, length 5025 bases, 5 prime target bases 1-1665 AFFX-r2-Hs28SrRNA-5 AFFX-r2-Hs28SrRNA-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database M11167.1 Human 28S rRNA sequence, length 5025 bases, 3 prime target bases 3331-4995 AFFX-r2-Hs28SrRNA-M AFFX-r2-P1-cre-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database Bacteriophage P1 /GEN=cre /DB_XREF=gb:X03453.1 /NOTE=SIF corresponding to nucleotides 1032-1270 of gb:X03453.1 /DEF=Bacteriophage P1 cre gene for recombinase protein. AFFX-r2-P1-cre-3 AFFX-r2-P1-cre-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database Bacteriophage P1 /GEN=cre /DB_XREF=gb:X03453.1 /NOTE=SIF corresponding to nucleotides 581-1001 of gb:X03453.1 /DEF=Bacteriophage P1 cre gene for recombinase protein. AFFX-r2-P1-cre-5 AFFX-ThrX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrB /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 1689-2151 of gb:X04603.1 /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). AFFX-ThrX-3 AFFX-ThrX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrC /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 288-932 of gb:X04603.1 /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). AFFX-ThrX-5 AFFX-ThrX-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=thrC, thrB /DB_XREF=gb:X04603.1 /NOTE=SIF corresponding to nucleotides 995-1562 of gb:X04603.1, not 100% identical /DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). AFFX-ThrX-M AFFX-TrpnX-3_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=trpC, trpF /DB_XREF=gb:K01391.1 /NOTE=SIF corresponding to nucleotides 3790-4368 of gb:K01391.1, not 100% identical /DEF=B.subtilis tryptophan (trp) operon, complete cds. AFFX-TrpnX-3 AFFX-TrpnX-5_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=trpE, trpD /DB_XREF=gb:K01391.1 /NOTE=SIF corresponding to nucleotides 1953-2483 of gb:K01391.1, not 100% identical /DEF=B.subtilis tryptophan (trp) operon, complete cds. AFFX-TrpnX-5 AFFX-TrpnX-M_at --Control Homo sapiens Oct 6, 2014 Control sequence Affymetrix Proprietary Database B. subtilis /GEN=trpD, trpC /DB_XREF=gb:K01391.1 /NOTE=SIF corresponding to nucleotides 2880-3359 of gb:K01391.1, not 100% identical /DEF=B.subtilis tryptophan (trp) operon, complete cds. AFFX-TrpnX-M